bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of Physical Properties for Activated Carbon from Garlic Skin
Authors: Mardiah Miftah Ainul , Awitdrus Awitdrus , Farma Rakhmawati , Taer Erman
Published: November 2021

Abstrak. Karbon aktif yang berasal dari biomassa telah menjadi bahan material dasar yang sudah digunakan secara luas untuk berbagai aplikasi eperti penyerapan, absorben, elektroda, penyimpan energi, dan aplikasi lainnya. Oleh karena itu perlu untuk pengoptimalkan sumber mentah karbon aktif berbiaya rendah dan memiliki porositas yang tinggi.  Biomassa kulit bawang putih sebagai bahan dasar pembuatan karbon aktif melalui proses pra-karbonisasi, aktivasi kimia dengan aktivator KOH dan ZnCl2 dengan masing-masing kosentrasi sebesar 0,25 M, 0,5 M, dan 0,75 M dan tanpa aktivator kimia. Proses karbonisasi dengan suhu 600°C dialiri gas nitrogen dan diaktivasi fisika dengan suhu 850°C. Penyusutan massa karbon sebesar 29,4%. Nilai densitas dari elektroda karbon untuk aktivator KOH dengan kosentrasi 0,5M yaitu 0,64 g.cm-3dan untuk aktivator ZnCl2 dengan kosentrasi 0,5M yaitu 0,71 g.cm-3. Gugus fungsi yang dimiliki elektroda kulit bawang putih diidentifikasi sebagai C-C, C C (alkuna), C-H (alkana), dan (O-H) yaitu pada bilangan gelombang 1600 cm-1, 1500 cm-1, 2950 cm-1 dan 2900-3600 cm-1. Hasil penelitian menunjukkan bahwa pada aktivator KOH dan ZnCl2 dengan kosentrasi 0,5 M kondisi terbaik untuk variasi guna menunjang pengoptimalkan sumber mentah karbon aktif dan bisa digunakan dalam berbagai apliasi yang lebih luas. Abstract. Activated carbon derived from biomass has become a basic material that has been used widely for various applications such as absorption, absorbent, electrodes, energy storage, and other applications. Therefore, it is necessary to optimize the raw source of activated carbon which is low cost and has high porosity. Garlic skin biomass as a basic material for making activated carbon through a pre-carbonization process, chemical activation with KOH and ZnCl2 activators with concentrations of 0,25 M, 0,5 M, and 0,75 M respectively and without chemical activators. The carbonization process with a temperature of 600°C is flowed with nitrogen gas and is physically activated at a temperature of 850°C. Shrinkage of carbon by 29.4%. The density value of the carbon electrode for the KOH activator with a concentration of 0.5M is 0.64 g.cm-3 and for the ZnCl2 activator with a concentration of 0,5M is 0,71 g.cm-3. The functional groups possessed by the garlic skin electrode were identified as C-C, C = C (alkynes), C-H (alkanes), and (O-H), namely at the wave numbers 1600 cm-1, 1500 cm-1, 2950 cm-1 and 2900-3600 cm-1. The results showed that the KOH and ZnCl2 activators with a concentration of 0.5 M were the best conditions for variation in order to optimize the raw source of activated carbon and could be used in a wider variety of applications.
Public administration in the Republic of Belarus: principles for sustainable development
Authors: Pilgun E. V. , Leshenyuk O. N.
Published: November 2021

Introduction. The article describes the principles of building state policy for the implementation of sustainable development goals in the Republic of Belarus. The authors analyse the compliance of the Belarusian national legislation with the principles of effective public administration in the interests of sustainable development.

Material and methods. The study is based on general scientific and special methods. In view of the nature of the researched issues, the comparative research of the legal base of the Republic of Belarus, as well as analogy were of particular importance. Much attention was paid to the analysis of the National Concept of Sustainable Development of the Republic of Bela­rus until 2035 and the Roadmap for the implementation of the SDGs in the Republic of Belarus.

Results. The effectiveness of public administration should be assessed by the fol­lowing parameters: security, international recognition, the ability of the state to pro­vide access to quality education and health care, the ability to involve the regions, the ability to provide basic infrastructure (transport capabilities, registration, statistics), the ability to replenish the treasury – taxation, the ability to organize management: the structure of public administration, procedures and selection of management person­nel, rational consumption of goods and services, maximum conservation of ecosystems in the process of natural resource management, cooperation with international part­ners and international organizations, development of integration processes with the countries of the Eurasian Economic Union.

Discussion and Conclusions. Today it is necessary to take into consideration that both Belarus and Russia are involved in the implementation of the UN SDGs as part of the implementation of the Union State project. So, it is extremely important to harmonize our approaches, including in matters of effective public administration. And it is necessary to introduce common criteria for evaluating efficiency, which can have a positive effect through the synergy of both systems, to coordinate public admin­istration in both countries. In addition, joint implementation, and preparation of joint projects in terms of improving public administration should be carried out.
Conditions for Success: Indigenous Youth Reflections on Their Experiences with Canadian Education Systems
Authors: Reddington Sarah , Theunissen Shane , MeDrano Jonathon
Published: November 2021

This paper brings forward the reflections of 30 Indigenous youth from across Canada and their first voice perspectives with Canadian education systems. A central component of the project was to obtain youths’ understandings of education in Canada and to seek their recommendations on ways to improve education for Indigenous youth. Accessing Indigenous youths’ experiences is important as their capacities to have successful and equitable educational experiences are strongly hindered by colonial settler policy and systemic institutional racism. Indigenous scholars have appealed for changes to education systems with a focus on challenging colonial relations of power and the multiple oppressions Indigenous youth experience when educated under Eurocentric practices. Our methodological framework is located within a relational paradigm as a mechanism to ignite dialogue and prioritize Indigenous voices in education. Our building of relations began with a sharing circle held at our Mount Saint Vincent University’s Wigwaum. Our Indigenous colleague and co-author, Jonathon MeDrano, explains how sharing circles provide equitable opportunities for people to share their ideas and respective worldviews. We then facilitated reflective journaling workshops with the youth. The young people’s reflections in this paper identify the compelling need to address systemic racism, stereotypes, and to challenge normative and colonizing structures that generate discrimination. Moreover, the young people soundly indicated that education systems in Canada require much larger integrations of Indigenous ways of knowing and being in all aspects of delivery (i.e. language, culture, Indigenous teachings), including more Indigenous counsellors to support their mental well-being.
ANALISIS PENGARUH PERTUMBUHAN EKONOMI, KETIMPANGAN PENDAPATAN, DAN INDEKS PEMBANGUNAN MANUSIA TERHADAP INDEKS KEBAHAGIAAN DI INDONESIA TAHUN 2014 DAN 2017
Authors: Sodik Jamzani , Febriantikaningrum Bella , Purwiyanta Purwiyanta
Published: November 2021

Penelitian ini bertujuan untuk: (1) menganalisis pengaruh pertumbuhan ekonomi terhadap indeks kebahagiaan, (2) menganalisis pengaruh kesenjangan pendapatan terhadap indeks kebahagiaan, (3) menganalisis pengaruh indeks pembangunan manusia (IPM) terhadap kebahagiaan. indeks di 33 provinsi tahun 2014 dan 34 provinsi pada tahun 2017 kemudian membandingkan hasil analisis pada kedua tahun tersebut. Penelitian ini menggunakan data sekunder; indeks kebahagiaan, pertumbuhan ekonomi, kesenjangan pendapatan, dan IPM yang bersumber dari Badan Pusat Statistik. Alat analisis yang digunakan adalah Ordinary Least Squares (OLS). Berdasarkan hasil analisis, pertumbuhan ekonomi tahun 2017, kesenjangan pendapatan tahun 2014 dan 2017 tidak berpengaruh signifikan terhadap indeks kebahagiaan. Sedangkan pertumbuhan ekonomi tahun 2014 dan IPM tahun 2014 dan 2017 berpengaruh positif dan signifikan terhadap indeks kebahagiaan.
ASSESSMENT OF THE COMPETITIVENESS OF INDUSTRIAL PRODUCTION INFLUENCE ON THE FOREIGN ECONOMIC ACTIVITY DEVELOPMENT UNDER THE CONDITIONS OF GLOBALIZATION
Authors: Akymenko Olena
Published: November 2021

The article proves that the effective economic development of Ukraine is facilitated by foreign economic relations, which are a determining factor in the development and modernization of the economy, an important step towards solving many social problems and a driver of scientific and technological development. It is proved that the revival of foreign economic activity will promote the country's integration into the international economic space and will determine it not just as a partnership and mutually beneficial cooperation, but as a process that will serve as an effective means of solving global problems. The most significant in nature means of economic regulation of foreign economic activity depending on its impact on the competitive advantages of the enterprise. The expediency of determining the level of competitiveness of industry taking into account the important structural characteristics (the level of industrial economy, specialization of industry, its internal and external efficiency) is proved. The author's definition of the concept of competitiveness of industrial production is given - its permanent ability to withstand competition due to the availability of appropriate potential provided a high level of efficiency and a means for further development of long-term strategies for long-term development and conquest of foreign markets.
Faktor-Faktor Yang Berpengaruh Terhadap Produksi Padi Di Desa Pamotan Kecamatan Kalipucang Kabupaten Pangandaran
Authors: Walis Nunu Rangga , Setia Budi , Isyanto Agus Yuniawan
Published: November 2021

Penelitian ini bertujuan untuk mengetahui Faktor-faktor apa saja yang berpengaruh terhadap produksi padi di Desa Pamotan Kecamatan Kalipucang Kabupaten Pangandaran, dan mengetahui pendapatan yang diperoleh petani padi di Desa Pamotan Kecamatan Kalipucang Kabupaten Pangandaran. Objek penelitian ini adalah petani padi sawah di Desa Pamotan Kecamatan Kalipucang Kabupaten Pangandaran. Data yang dipergunakan merupakan data primer dan data sekunder. Metode penarikan sampel menggunakan purposive sampling dan pemilihan daerah penelitian ditentukan secara sengaja. Analisis data dengan regresi berganda. Hasil pada penelitian ini menunjukan bahwa faktor-faktor yang berpengaruh nyata terhadap produksi padi adalah variabel luas lahan (X1) dan pupuk urea (X4). Rata-rata pendapatan yang diperoleh petani adalah Rp. 3.092.700,00. Pendapatan petani padi sawah ditentukan oleh hasil produksi padi. Sehingga dapat disimpulkan bahwa faktor-faktor produksi tersebut berpengaruh terhadap produksi padi di Kecamatan Kalipucang Kabupaten Pangandaran.
Persepsi Petani Terhadap Usahatani Lahan Pekarangan
Authors: Hermawan Dede , Isyanto Agus Yuniawan , Setia Budi
Published: November 2021

Alih fungsi lahan yang meningkat dari lahan pertanian menjadi non pertanian dinilai sudah tidak terkendali, menyusul pesatnya sector industri dan pemukiman di Indonesia, Praktek alih fungsi lahan tersebut melahirkan satu kekuatiran tersendiri terhadap ketersediaan pangan masyarakat. Penelitian ini bertujuan untuk mengetahui mengetahui sejauh mana Tingkat Persepsi Petani terhadap Program Pemanfaatan Lahan Pekarangan  di Desa Ciganjeng Kecamatan Padaherang Kabupaten Pangandaran. Jenis penelitian yang akan digunakan dalam penelitian ini adalah metode  studi kasus. Pemilihan lokasi dilakukan secara sengaja (Purposive) dengan pertimbangan  bahwa Desa Ciganjeng merupakan desa dengan warga yang banyak menerapkan pemanfaatan lahan pekarangan. Metode pengambilan sampel dilakukan dengan metode sampel acak sederhana (Simple Random Sampling). Dengan tingkat presisi 15% dari jumlah petani yang ada maka didapatkan hasil sebanyak 39 orang petani sebagai responden dari populasi sebanyak 275. Hasil penelitian menunjukkan presepsi petani terhadap usahatani lahan pekarangan adalah berpresepsi baik dengan total skor 1.413 dengan rata-rata skor 36,23 dari 10 pertanyaan yang diberikan kepada para petani yang dijadikan responden, Faktor-faktor yang mendorong petani dalam mengusahakan usahatani lahan pekarangan adalah adanya kesadaran dari diri para petani itu sendiri untuk memanfaatkan lahan pekarangan rumah mereka yang kosong untuk ditanami dengan berbagai jenis tanaman sayuran untuk memenuhi kebutuhan sehari-hari mereka bahkan dapat memberikan pendapatan dari hasil usahatani lahan perakarangan yang mereka kelola. Faktor-faktor eksternal yang dapat mendorong petani dalam menjalakan usahatani lahan pekarangan yaitu, adanya dorongan dari pihak pemerintahan setempat yaitu dari pihak Desa setempat dan BPP Kecamatan setempat yang dijalankan oleh penyuluh untuk merangkul, membina dan memberikan ilmu-ilmunya kepada para petani lahan pekarangan supaya dapat lebih berkembang lebih baik lagi.
Analisis Efisiensi Pemasaran Cabai Merah Varietas Tanjung
Authors: Saputra Aceng Romli , Setiawan Iwan , Setia Budi
Published: November 2021

Tujuan penelitian untuk menganalisis : (1) Saluran pemasaran pada cabai merah varietas Tanjung, (2) Besaran Biaya, marjin serta keuntungan pemasaran pada cabai merah varietas Tanjung, (3) Besaran bagian harga yang diterima produsen cabai merah varietas Tanjung, dan (4) Efisiensi pemasaran cabai merah varietas Tanjung. Penelitian yang didesain secara kuantitatif dengan menggunakan metode survei ini dilakukan di Desa Maparah Kecamatan Panjalu Kabupaten Ciamis pada bulan Mei-Julli tahun 2021. Sebanyak 36 petani diambil dengan acak sederhana (simple random sampling) dari 180 orang populasi petani. Untul lembaga pemasaran diambil secara sengaja menggunakan snowball sampling sehingga didapat sampel lembaga pemasaran 1 responden pedagang besar dan 10 pengecer. Untuk penelitiannya menghasilkan : (1) Cabai merah Tanjung memiliki satu saluran pemasaran, yang rantainya dimulai dari   Petani ke Pedagang besar lalu ke Pedagang pengecer dan ke Konsumen,  (2) Biaya pemasaranya Rp. 1.096,17, Marjin pemasarannya Rp. 12.000/Kg serta pemasaran memiliki keuntungan Rp. 11.403,83/Kg, (3) Untuk farmen sharenya sebesar 50,00 persen; dan (4) Tingkat efisiensi pemasaran sebesar 4,38 persen.
Pemberdayaan Forum Pemuda Lintas Agama (FPLA) dalam Penguatan Kapasitas Anggota Sebagai Aktor Penggerak Toleransi di Kabupaten Kulon Progo Yogyakarta
Authors: Syafi’ie M. , Lukmanul Hakim Alif , Heryansyah Despan
Published: November 2021

Indonesia is a country built on the foundation of multiculturalism. Since the beginning, the founders of this Republic were aware of this, so that the first principle of Pancasila reads God Almighty. This is an important indication that Indonesia is not a religious state, all religions before the state have the same and equal position. The state, in fact, guarantees all citizens to be free to worship according to their respective religions and beliefs. However, the life of the nation, state and society in a concrete sense is not always as good as it is conceived. In practice, religious primordialism, religious fundamentalism, and even radicalism still frequently occur. According to certain religious teachings, this group isolates, or even is hostile to, adherents of other different religions. The forms of this movement vary, from the most violent in the form of acts of terrorism, to the most gentle in the form of rejection of other parties who are different. Young people who have just entered high school and university are easy targets of this movement. Whereas in fact, the Indonesian nation from a cultural historical aspect, is a nation that loves harmony, a nation that respects and respects differences, united in the spirit of mutual cooperation. However, the spirit or soul is often covered by the massive fundamentalism movement carried out by this particular group. Therefore, departing from the above problems, we are collaborating with the Kulon Progo Interfaith Youth Forum (Forum Pemuda Lintas Agama) to organize activities that can foster unity and tolerance, especially among youth in Kulon Progo. Kulon Progo is used as an object because it is in a transition period to become an urban area, which of course there will be many identity intersections in the community. The activity was successfully held for two online discussions. The first discussion discussed tolerance and harmony between religions in a more general context. How is the situation in the world and in Indonesia itself.This was followed by a second discussion by presenting representatives from several religions, to convey the perspective of tolerance from their respective religious teachings.

Keyword: Interfaith, Tolerance, Youth
Pendampingan Pada Komunitas Anak Disabilitas di Kota Pekanbaru Melalui Pemahaman Hak-Hak Aksessibilitas
Authors: Firmanda Hengki , Firdaus Emilda , Rani Nabella Puspa
Published: November 2021

The first fact is still found by parents who have not paid special attention to children with disabilities, resulting in violations of the rights of children with disabilities. The second fact is that the legal instruments are still weak and the regulations have not been fully implemented. These facts are an inhibiting factor in the development of children with disabilities. The purpose of this activity is so that children with disabilities know what their rights are, so that children with disabilities still feel respected by their presence. The output of this activity is the fulfillment of accessibility rights for children with disabilities in their growth and development in the social environment. The result of this activity is that children with disabilities know their rights, so that discrimination against them is not allowed. Children with disabilities also know that they have special rights guaranteed by laws and regulations.
A PRIMEIRA RECEPÇÃO DE NIETZSCHE NO BRASIL PELA ESCOLA DE RECIFE
Authors: Pantuzzi Tiago Lemes
Published: November 2021

A Faculdade de Direito de Pernambuco é o ponto inicial da recepção brasileira de Nietzsche. A Escola de Recife surge de um movimento intelectual dentro da faculdade pernambucana que, entre seus objetivos, busca construir uma identidade cultural nacional que se distancie do predomínio europeu. Em meio a esse movimento, encontramos a citação explícita mais antiga do filósofo alemão que nos leva ao texto de Tobias Barreto de 1876. Nesse período, muitas obras que fariam parte da formação de alunos vindouros, como José Oiticica e Gilberto Amado, são adquiridas pela instituição pernambucana.
PULSIONALIDADE E CONSCIÊNCIA (BEWUßTSEIN) EM NIETZSCHE
Authors: Krieger Saulo
Published: November 2021

Este artigo pretende mostrar que a consciência (Bewußtsein) em Nietzsche, ao modo de um “‘conhecer’ o que se pensa”, não é uma consciência de introspecção e de acesso direto a si mesma, mas de transposições e expressividade. O filósofo chega a essa concepção ao rastrear os traços básicos do ato de pensar já num nível infraconsciente, dos impulsos orgânicos. Mais precisamente, chega a um "pensamento pulsional" ao deparar com uma linguagem entabulada pelos impulsos – uma linguagem figurativa, metafórica e transposicional.
NOTA SOBRE O PLANO DE ALÉM DO BEM E DO MAL DE NIETZSCHE
Authors: Strauss Leo , Mendes (Tradutor) Elvis Oliveira
Published: November 2021

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NIETZSCHE E LEO STRAUSS: PERSPECTIVISMO MORAL E PENSAMENTO POLÍTICO
Authors: Mendes Elvis de Oliveira
Published: November 2021

O presente artigo tem como propósito mostrar que, na interpretação do filósofo político teuto americano Leo Strauss, o perspectivismo nietzschiano é uma concepção filosófica complexa, que atua em duas dimensões diferenciadas. Por um lado, o perspectivismo de Nietzsche aparece como a elaboração de uma visão relativista e iconoclasta da moralidade, que propugna a ideia de que todas as “verdades” morais e metafísicas são meras “interpretações” ou criações humanas, cujo significado é, pois, historicamente condicionado, por outro lado, esse mesmo perspectivismo pretende ser a descoberta de uma verdade que transcende todas as “verdades” históricas, vale dizer, a descoberta de uma verdade inumana, que, situada para além do bem e do mal, ultrapassa todas as verdades forjadas pelo pensamento humano. Para Strauss, tal verdade, tem a ver com a descoberta do caráter absurdo, imoral e irracional da existência – uma descoberta terrível, letal e devastadora, cuja visão é insuportável para os homens. Diante desses elementos, o pensamento nietzschiano teria sido conduzido à ideia de que as verdades morais, apesar de fictícias, são necessárias ao homem, na medida em que elas são responsáveis pela manutenção de uma atmosfera protetora da existência, sem a qual a vida em sociedade seria insustentável.Palavras-chaves: Verdade; Moral; Perspectivismo; Strauss; Nietzsche
A Study on the Adaptation of The Anatomy Curriculum in Medical Faculties to the National Core Curriculum-2014: Anatomy-CEP Version I
Authors: ADIGÜZEL Esat
Published: November 2021

Aim: The National Medical Core Curriculum Program has been developed since 2001 to help keep the level of education in medical schools above high standards. The education in basic medical sciences should be adapted to the latest version of the national undergraduate medical education core curriculum, published in 2020. This study, which was planned on the basis of the need for adaptation of the curriculum in basic medical sciences to the national core education program in the field of medical education, was carried out with the decision of the Board of the Turkish Society of Anatomy and Clinical Anatomy with the aim of adaptation the anatomy course contents applied in medical faculties to the National Core Curriculum for Undergraduate Medical Education - 2014.Methods: The planning of the study was based on the "systematic anatomy education approach", which is commonly used in anatomy education. The prepared report was named as Anatomi-ÇEP 1st version, and a work plan was made to keep the new versions up-to-date through this report. Workshops were held with the participation of the faculty members of the anatomy department in the creation of the adaptation lists. Consensus questionnaires participated by faculty members who teach anatomy were used in the acceptance of the adaptation lists.Results: Two workshops were held in the process. In these workshops, the relationships between anatomy subjects and "Core Diseases and Clinical Problems" in "Undergraduate Medical Education National Core Education Program- 2014" were determined. Since the "Core Diseases and Clinical Problems" list was in alphabetical order, the lists were re-created in a systematic order according to the anatomy course contents. The lists were presented to the opinions of faculty members working in the Anatomy Departments twice and a consensus decision was made. In "Anatomy-ÇEP 1st Edition", basic diseases in "UÇEP2014" have been adapted to the basic topics in anatomy education, but they have not been associated with symptoms and conditions and basic medical practices. Conclusions: With this article, it was aimed to share what was done in "Anatomy-ÇEP 1st Edition" with academicians, and to provide data for studies to be carried out to adapt the changes brought by "UÇEP-2020" to "Anatomy-ÇEP" with the feedback to be received.
Grand Rounds Model in terms of Continuing Medical Education and Lifelong Learning
Authors: KORKMAZ Güneş , AYTUĞ KOŞAN Ayşen Melek , TORAMAN Çetin
Published: November 2021

Aim: The rapid change in many fields in the global sense and the need for transformation due to this change has also affected the field of medical sciences; therefore, revisions have been required in medical education practices. For this reason, medical education is considered as one of the fields where change occurs fast. This study aims to examine the Grand Rounds model in terms of continuing medical education and lifelong learning through the analysis of its planning, implementation, and evaluation process. Methods: This traditional literature review, in the context of continuing medical education and lifelong learning, was conducted to examine the planning, implementation and evaluation processes of grand rounds, especially in the United States. In Pubmed, Scopus and Google Scholar search engines, the keywords "Clinical Rounds", "Medical Rounds", "Bedside Teaching Rounds", "Medicine Rounds" and "Ward Rounds", which are called "classical clinical learning cycle", were searched. Then, the studies that included the term “Grand Rounds” model were examined.Results: The grand rounds are designed to follow up-to-date diagnosis and treatment methods, to encourage knowledge sharing among faculty members, to contribute to the lifelong learning skills of students and faculty members, to create an active learning environment for assistants and students, and to share the faculty’s experiences with other stakeholders. It has been observed that the Grand Rounds, which was created in the context of adult learning theory and lifelong learning, has a more comprehensive process than traditional clinical rounds, is applied both in pre-graduate and postgraduate medical education and with the participation of health professionals from various disciplines. The most important stage of the Grand Rounds is planning. Therefore, there are some key elements that should be considered by the organizing committee that will carry out the planning process. These elements include shaping the content around the themes that will meet the needs of the participants, determining the appropriate learning outcomes, and deciding on the presentations that will contribute to the development of students' skills such as clinical reasoning, problem solving and decision making. During the implementation process, sufficient time should be allowed for the participants to discuss, interact, and share information about the subject. After Grand rounds, both the content in the learning cycles and the presenters should be evaluated with valid and reliable tools.Conclusions: Integration of Grand rounds into continuous medical education in Turkey is strongly recommended in terms of providing broader lifelong learning opportunities for medical students, resident physicians and medical educators.
One-Pot Preparation of (NH)-Phenanthridinones and Amide-Functionalized [7]Helicene-like Molecules from Biaryl Dicar-boxylic Acids
Authors: Furuta Takumi , Murai Takuya , Xing Yongning , Kurokawa Mayu , Kuribayashi Toshifumi , Nikaido Masanori , Elboray Elghareeb E. , Hamada Shohei , Kobayashi Yusuke , Sasamori Takahiro , Kawabata Takeo
Published: November 2021

A one-pot transformation of biaryl dicarboxylic acids to (NH)-phenanthridinone derivatives based on a Curtius rearrangement and subsequent basic hydrolysis was developed. This method is also applicable for the preparation of optically active amide-functionalized [7]helicene-like molecules. Furthermore, aza[5]helicene derivatives with a phosphate moiety were isolated as a product of the Curtius rearrangement step in the case of substrates that bear chalcogen atoms. The stereostructures of these products, revealed by X-ray diffraction analysis, suggested that chalcogen-bonding and pnictogen-bonding interactions might contribute to their stabilization. The configurational stability of the helicene-like molecules and their chiroptical properties were further investigated.
Efficient Electrochemical Reduction of CO2 to Formate in Methanol Solutions by Mn Functionalized Electrodes in the Presence of Amines
Authors: Marocco Studardi Francesca , Tiozzo Arianna , Rotundo Laura , Gobetto Roberto , Nervi Carlo , Leclaire Julien
Published: November 2021

Carbon cloth electrode modified by covalently attaching a manganese organometallic catalyst is used as cathode for the electrochemical recuction of CO2 in methanol solutions. Six different amines are employed as co-catalyst in millimolar concentrations, which coupled to the increased solubility of CO2 in methanol enhance the formate production, switch the selectivity toward formate anion, and in the case of pentamethyldiethylentriamine (PMDETA) resulted in an impressive TONHCOO– of 2.8×104. We demonstrate that the protonated PMDETA is formed in methanol solution by simply bubbling CO2, which is the responsible for a barrierless transformation of CO2 to formate via the reduced form of the Mn catalyst covalently bonded to the electrode surface. These findings pave the way for more efficient transformation of CO2 into liquid fuel and shed light on the electrochemical mechanism
In Silico Modeling and Scoring of PROTAC-Mediated Ternary Complex Poses
Authors: Liao Junzhuo , Nie Xueqing , Unarta Ilona , Ericksen Spencer , Tang Weiping
Published: November 2021

Proteolysis targeting chimeras (PROTACs) are bifunctional molecules that can induce the ubiquitination of targeted proteins via the formation of ternary complexes between an E3 ubiquitin ligase and a target protein. The poly-ubiquitinated target protein will be escorted to the proteasome for degradation. Rational design of PROTACs require knowledge of an accurate configuration of the PROTAC induced ternary complex. This study demonstrates that native ternary poses can be distinguished by scoring candidate poses based on the pose residence time. The scoring is essentially heat-and-dissociate trials of candidate poses sampled by MD and pre-ranked by the classic MM/GBSA method. It is practical, simple to use and self-intuitive, relying on the observation that the assumed more stable native crystal ternary poses maintained a longer residence time than non-native ones at both room and higher temperatures. A time score and temperature score were generated from multiple replicate trajectories. These scores were able to correctly identify the native pose from non-native ones in all the systems examined. The absolute numbers were comparable across different systems in all currently available VHL and CRBN-containing ternary crystal structures. Therefore, it is also possible to provide an empirical criteria for unresolved ternary structures that under the conditions of this study. If a ternary pose is stable up to over a certain threshold score, it is likely a native pose. The success of the method is in part attributed to the dynamic nature of the pose change analysis which naturally involves entropic effects, one that is intrinsically unavailable with faster static scoring methods that consider molecular mechanical energy only. Protein-protein binding entropy is much more significant than in protein-ligands binding. The success is also attributed to the fact that the protein structures themselves were all stable in the short heating trials.
Sucesión anómala
Authors: Ferrero-Costa Augusto
Published: November 2021

No presenta resumen
El derecho internacional del trabajo y la libertad de asociación
Authors: Álvarez Vita Juan
Published: November 2021

No presenta resumen
"No se cumple" en torno a la ineficiencia de nuestro sistema legal
Authors: Perla-Anaya José
Published: November 2021

"It is not fulfilled" around the inefficiency of our legal system
PHYSICAL AND CHEMICAL INVESTIGATION OF THE AUTHENTICITY OF PARACETAMOL
Authors: Шачнева Кристина Сергеевна , Баранова Надежда Владимировна , Феофанова Мариана Александровна
Published: November 2021

Подтверждено наличие п-ацетаминофена методами спектрофотометрическим и ИК-спектроскопии в лекарственных препаратах.

The presence of p-acetaminophen was confirmed by spectrophotometric and IR-spectroscopy methods in medicinal preparations
SONOCHEMICAL PROCESSING INDUSTRIAL AND BIOLOGICAL МАТЕRIALS
Authors: Шабловский Ярослав Олегович
Published: November 2021

Проанализированы технологически значимые факторы, обеспечивающие возможности управления сонохимическими процессами. Выявлены качественные и количественные закономерности влияния акустических воздействий на химические процессы в гомогенных и в гетерогенных реакционных системах. Показано, что сонохимический эффект может быть не только положительным (инициирование химической реакции), но и отрицательным (подавление реакции). Соответственно, в экстремальном случае возможен сонохимический резонанс (максимум эффективности акустического воздействия) либо сонохимический антирезонанс (минимум эффективности акустического воздействия). Акустическая обработка конденсированных сред в режиме стоячей волны позволяет контролировать характерный размер частиц плотных фракций: укрупнять частицы кристаллического осадка (соноиндуцированный эффект Тананаева) либо, наоборот, измельчать плотную фазу без использования мелющих тел.

The paper deals with technologically essential factors governing sonochemical processes. Qualitative and quantitative characteristic features of sonoinduced chemical processes in homogeneous and heterogeneous reaction systems are revealed and discussed. A sonochemical effect can be either positive (promoting a reaction) or negative (suppressing a reaction). In an extreme case a sonochemical resonance or a sonochemical antiresonance can occur. Ultrasonic processing condensed media in a standing-wave regime enables to control the grain size of dense fractions. Namely, the sediment grain size can be enhanced (Tananayev sonoinduced effect) or, vice versa, a dense phase can be comminuted without grinding.
EFFECT OF COMPLEXONS, DERIVATIVES OF SUCCINIC ACID, ON THE FORMATION OF CAROTENOIDS IN GREEN PLANTS
Authors: Смирнова Татьяна Ивановна , Тумасьева Ирина Геннадьевна , Толкачева Людмила Николаевна , Никольский Виктор Михайлович
Published: November 2021

На основании обобщения результатов многолетних лабораторных и полевых опытов обнаружена зависимость уровня содержания жёлтых фотосинтетических пигментов в растениях от внекорневой обработки растворами комплексонов. Комплексоны, производные янтарной кислоты (иминодиянтарная кислота, этилендиаминдиянтарная кислота, диаминоциклогександиянтарная кислота) способствуют накоплению каротиноидов в зелёных растениях, а этилендиаминтетрауксусная кислота существенно не влияет на их содержание.

Based on the generalization of the results of many years of laboratory and field experiments, the dependence of the content of yellow photosynthetic pigments in plants on foliar treatment with solutions of complexones was found. Complexones, derivatives of succinic acid (iminodisuccinic acid, ethylenediaminedisuccinic acid, diaminocyclohexanedisuccinic acid) contribute to the accumulation of carotenoids in green plants, and ethylenediaminetetraacetic acid does not significantly affect their content.
THE USE OF RuO DEPOSITED ON HZSM-5 WITH A DIFFERENT SILICATE MODULUS IN THE REACTION OF LEVULINIC ACID HYDROGENATION
Authors: Абусуек Диаля Атия , Никошвили Линда Жановна
Published: November 2021

В работе проводилось исследование рутений-содержащих катализаторов на основе цеолитов HZSM-5 с различным кремнеземным модулем (40, 80 и 400) в реакции гидрирования левулиновой кислоты (ЛК) до гамма-валеролактона. Была изучена зависимость активности композитов Ru/HZSM-5 от кремнеземного модуля выбранного цеолита и от содержания диоксида рутения на поверхности. Показано, что образец Ru/HZSM-5 с кремнеземным модулем 40 позволяет в достаточно мягких условиях (температура 100С, парциальное давление водорода 1 МПа) достичь 98% конверсии ЛК за 60 мин реакции в водной среде.

In this work, the study of ruthenium-containing catalysts based on zeolites of the HZSM-5 type with different silicate modulus (40, 80 and 400) in the reaction of levulinic acid (LA) hydrogenation to gamma-valerolactone was carried out. The dependence of the activity of Ru/HZSM-5 composites on the silicate modulus of the selected zeolite and on the content of ruthenium dioxide on the surface was studied. It is shown that the Ru/HZSM-5 sample with a silicate modulus equal to 40 allows achieving 98% of LA conversion in 60 minutes of the reaction in an aqueous medium under mild conditions (temperature 100°C, 1 MPa of partial hydrogen pressure).
DEVELOPMENT OF THE SCIENTIFIC BASIS OF MODERN RESOURCE-SAVING TECHNOLOGY FOR THE CONVERSION OF PLANT BIOMASS INTO ISOSORBIDE
Authors: Филатова Анастасия Евгеньевна , Ожимкова Елена Владимировна , Сульман Александрина Михайловна , Губская Елена Мечиславовна
Published: November 2021

Данная статья посвящена обзору разработок научных основ современной ресурсосберегающей технологии конверсии растительной биомассы в изосорбид. В статье проведен анализ литературных источников, позволяющий сделать вывод о современных исследованиях, направленных на изучение процесса конверсии растительной биомассы. Кроме того, на основании обзора можно говорить о том что изосорбид является наиболее перспективным продуктом конверсии растительной биомассы

This article is devoted to the review of the development of the scientific foundations of the modern resource-saving technology for the conversion of plant biomass into isosorbide. The article analyzes the literature sources, which allows us to draw a conclusion about modern research aimed at studying the process of conversion of plant biomass. In addition, based on the review, it can be said that isosorbide is the most promising product of the conversion of plant biomass.
FUNCTIONALIZATION OF THE SURFACE OF HYPERCROSSLINKED POLYSTYRENE FOR CATALYST SYNTHESIS
Authors: Дмитриева Анастасия Алексеевна , Щипанская Елена Олеговна , Степачёва Антонина Анатольевна , Монжаренко Маргарита Александровна , Маркова Мария Евгеньевна , Сульман Михаил Геннадьевич , Матвеева Валентина Геннадьевна
Published: November 2021

Нанесенные наноразмерные катализаторы широко используются в различных процессах химической технологии. При этом особые требования предъявляются к носителю, используемому при синтезе катализаторов. Сверхсшитые полимеры являются перспективными носителями, однако зачастую не имеют требуемых свойств (например, кислотности). Для придания дополнительных свойств возможно модифицировать поверхность полимеров различными веществами или функциональными группами. В данной работе проведено исследование способов модификации и веществ-предшественников кремнийсодержащей фазы для модификации поверхности сверхсшитого полистирола диоксидом кремния.

The supported nano-scale catalysts are widely used in different fields of chemical engineering. For the catalysts, the certain requirements are specified fort the catalyst supports. Hypercrosslinked polymers seem to be the prospective materials for the catalyst synthesis. However, polymeric matrices often do not meet some standards for catalyst supports (i.e. polymers are inert materials and do not have the acidic or basic properties). To infuse the additional properties to polymers it is possible to modify its surface with different compounds or functional groups. In this work, the study of the ways for the modification of the surface of hypercrosslinked polystyrene and silica-phase precursors was carried out.
KINETIC REGULARITIES OF NICKEL SULFURIC ACID LEACHING PROCESSES
Authors: Пичугина Анна Игоревна , Гончар Дарья Дмитриевна
Published: November 2021

В работе представлены результаты исследования кинетики сернокислого выщелачивания никеля из его сульфидов. В качестве модельных образцов выбраны синтезированные сульфиды никеля по составу и строению идентичные природным минералам: миллериту и хизлевудиту. Получены зависимости влияния скорости извлечения металла от концентрации серной кислоты, температуры, частоты вращения диска и продолжительности взаимодействия. Рассчитаны полиномиальные модели изучаемого процесса, преобразованные в уравнения скорости. Вычислены константы скорости и эмпирические значения энергии активации.

The paper presents the results of a study of the kinetics of sulfuric acid leaching of nickel from its sulfides. Synthesized nickel sulfides were selected as model samples, identical in composition and structure to natural minerals: millerite and heazlewudite. The dependences of the influence of the metal extraction rate on the concentration of sulfuric acid, temperature, disk rotation frequency and duration of interaction are obtained. The polynomial models of the process under study, transformed into velocity equations, are calculated. The rate constants and empirical values of the activation energy are calculated.
Up-regulation of ubiquitin–proteasome activity upon loss of NatA-dependent N-terminal acetylation
Authors: Kats Ilia , Reinbold Christian , Kschonsak Marc , Khmelinskii Anton , Armbruster Laura , Ruppert Thomas , Knop Michael
Published: November 2021

N-terminal acetylation is a prominent protein modification, and inactivation of N-terminal acetyltransferases (NATs) cause protein homeostasis stress. Using multiplexed protein stability profiling with linear ubiquitin fusions as reporters for the activity of the ubiquitin proteasome system, we observed increased ubiquitin proteasome system activity in NatA, but not NatB or NatC mutants. We find several mechanisms contributing to this behavior. First, NatA-mediated acetylation of the N-terminal ubiquitin–independent degron regulates the abundance of Rpn4, the master regulator of the expression of proteasomal genes. Second, the abundance of several E3 ligases involved in degradation of UFD substrates is increased in cells lacking NatA. Finally, we identify the E3 ligase Tom1 as a novel chain-elongating enzyme (E4) involved in the degradation of linear ubiquitin fusions via the formation of branched K11, K29, and K48 ubiquitin chains, independently of the known E4 ligases involved in UFD, leading to enhanced ubiquitination of the UFD substrates.
Nasionalisme Inggris dan Kekerasan Berbasis Kebencian terhadap Muslim Studi Kasus English Defence League
Authors: Hanif Muhammad Naufal , Wibisono Ignatius Satria , Yusuf Dedi , Zam Muhammad Valdy Akbar , Hartono Nigel Januar
Published: November 2021

Bangkitnya nasionalisme Inggirs telah dicatat dan diteliti secara baik sejak dekade 1990an, terlebih pasca-hasil Brexit, dengan catatan mengenai identitas Inggris yang mengambil bentuk ketidakamanan finansial, nostalgia atas masa lalu imperial, xenofobia, dan anti-elitisme. Pada waktu yang sama, kekerasan berbasis kebencian terhadap komunitas Muslim di berbagai kawasan Inggris juga telah diarsipkan dan dikaji dengan baik, dengan penjelasan mengenai motif pelaku mengarah pada penemuan individu-individu yang terperangkap dalam ketidakpercayaan mendalam terhadap non-Inggris dan ketakutan akan kehilangan identitasnya sebagai orang Inggris. Meskipun kedua fenomena ini memiliki fitur-fitur yang sangat mirip, jarang ditemukan penjelasan yang mengarah pada usaha untuk menghubungkan kedua fenomena kontemporer di lanskap identitas politik Inggris ini. Menggunakan contoh English Defence League yang sangat kontroversial serta pemimpinnya Tommy Robinson pada puncak aktivitas mereka di akhir dekade pertama abad ke-21, kami menemukan bahwa terdapat setidaknya korelasi kuat antara kedua fenomena dan kemungkinan nasionalisme Inggris sebagai salah satu penyebab penting yang secara langsung mengarah kepada kejadian-kejadian kejahatan berbasis kebencian untuk kaum minoritas di Inggris.
Klaster Industri Budaya sebagai Dasar Manuver Politik Korea Selatan
Authors: Tamba Asinauli
Published: November 2021

In July 2016, South Korea agreed with its military alliance, the United States to install Terminal High Altitude Area Defense (THAAD) on its territory. This agreement is the embodiment of the interests of the two countries that were integrated. The United States's interests in spreading influence in the East Asian region and South Korea's interests in protecting the country from North Korea's nuclear test practices on the Korean Peninsula. But the THAAD installation was rejected by China, which considers the instrument as the trigger of tensions in the region and hampering China’s dominance. In expressing its disapproval, China imposed economic sanctions by boycott on South Korean-owned cultural industrial products, namely hallyu. In October 2017, South Korea approved China's request to change its THAAD policy through points listed in the Three NOs. The significant changes in South Korean foreign policy are questionable in this study. This study uses the theory of neorealism as a logical thinking and suggests that hallyu as the main reason for the political maneuvering chosen by South Korea as a boycott of China as the main market share of the hallyu has crippled the South Korean economy. South Korea chose a bandwagoning strategy in the midst of threats in order to be able to maintain the production and distribution of cultural products which are currently the main source of foreign exchange for the country. This research uses qualitative research methods with data collection by literature study.

 

Keywords: South Korea, China, United States, THAAD, Boycott, Cultural Industry, Hallyu.
Diagnóstico qualitativo do Programa Nacional de Alimentação Escolar em oito municípios do Rio Grande do Sul
Authors: Heckler Dienifer , Figueredo Oscar Agustín Torres , Ferigollo Danielle , Kirsten Vanessa Ramos
Published: November 2021

O Programa Nacional de Alimentação Escolar (PNAE) é uma iniciativa que busca ampliar a oferta de alimentos para a comunidade escolar concomitantemente à valorização e ao apoio à agricultura familiar. A partir disso, o presente estudo teve como objetivo diagnosticar, de forma qualitativa, este programa federal como um mercado institucional, abrangendo oito municípios do Estado do Rio Grande do Sul: Carazinho, Pelotas, São Gabriel, Herval. Cerrito, Gramado, Porto Alegre e Caxias do Sul. Os dados foram obtidos mediante entrevistas com os gestores/nutricionistas, membros do Conselho de Alimentação Escolar (CAE), agricultores e técnicos de extensão rural. Os resultados demonstraram o efetivo funcionamento do PNAE, destacando as suas principais potencialidades e limitações no que se refere à comunicação entre os setores envolvidos na aquisição, cumprimento da lei e avanços e conquistas nestes municípios, tanto pelos membros da comunidade escolar como também pelos agricultores que participam do programa. Constatou-se que nesses municípios o PNAE está alcançando seus objetivos legais com algumas vicissitudes, mas procurando favorecer os produtores e os consumidores de gêneros alimentícios oriundos da agricultura familiar. Alguns aspectos observados se relacionam às exigências fitossanitárias, às chamadas públicas, as quais exigem melhor compreensão e comunicação entre gestores, técnicos e agricultores para o cumprimento efetivo da lei. Pode-se afirmar que este mercado institucional é uma grande oportunidade para a agricultura familiar, embora alguns aspectos devam ajustar-se de modo a atingir os objetivos propostos pelo programa.