bluuebunny/crossref_metadata_2025 huggingface dataset:
Introduzione. Umberto Gori e le Relazioni Internazionali in Italia
Authors: Cesa Marco , Lucarelli Sonia
Published: October 2022

Umberto Gori has held the first chair of International Relations in Italy and has been the first scholar to address a series of central topics in the analysis of foreign policy and international politics. Those who browse, even if only rapidly, his rich bibliography cannot but be struck by the great variety of the topics examined: from the first works of a predominantly legal nature, we move on to studies centered on methodological and epistemological issues, relations between states, analysis of foreign policy in general and Italian foreign policy in particular, Peace Research, strategic affairs, intelligence, and finally the impact of the information and digital revolution on international politics and contemporary strategy. What holds together so many different issues is, firstly, a constant attention to methodology and, secondly, a clear preference for a predominantly operational approach, in the belief that knowledge must always be functional to decision and action. These basic attitudes are reflected not only in his strongly characterized research agenda, but also in the twofold nature of his teaching commitment: on the one hand, Gori taught outside the university classrooms, at military and governmental institutions, for decades; on the other hand, he introduced issues traditionally reserved to diplomacy and security institutions into the Italian academic context. Such a propensity to build bridges between different worlds - academic, military, technological, diplomatic, financial - and a research vocation that has never failed make Umberto Gori a figure indissolubly linked to the birth and development of International Relations in Italy.
Resilient or Obsolete? Reflections on the Liberal World Order and its Crisis
Authors: Lucarelli Sonia
Published: October 2022

From its beginnings, in the aftermath of the first post-war period, the liberal order has significantly changed the texture, actors and tones of international politics, aiming to create institutions and rules that harnessed the forces that for centuries led political communities to wage war. Never fully realized, the liberal order has produced the most significant network of connections between societies, going so far as to make war unlikely in the areas where it has established itself most profoundly. An ambitious model which, refusing to separate the peaceful space of liberal democracy from the international one of Westphalian states, it promised widespread well-being, security and prospects for progress for individuals and groups. Today, however, many of its promises have been broken, illiberal actors have taken on ever-increasing economic and political weight, and the liberal world has become fragmented and weakened. Moreover, the crisis of liberal democracy within states and the phenomena of “autocratization”, as well as the difficulty of liberal societies in giving effective responses to the challenges posed by a rapidly evolving technological world, represent challenges that make the liberal order's resilience uncertain. This chapter aims to analyze the main features of the crisis of the liberal order to evaluate its possible evolution.
Technology acceptance model for Building Information Modelling Based Virtual Reality (BIM-VR) in cost estimation
Authors: Lee Minghui , Chai Changsaar , Xiong Yaoli , Gui Hunchuen
Published: October 2022

The accuracy of cost estimation during the preliminary stage of a construction project is imperative. However, owing to limited accessibility of information, the level of accuracy required at this stage of a project is extremely difficult to be attained. In like manner, the risks of budget shortages or cost overruns are likely to surge exponentially due to an incompetent or a lackadaisical approach towards life-cycle costing. Hence, this study proposes BIM-based VR as a preliminary estimating solution which is purported to nip the aforementioned issues in the bud. BIM-VR enables BQ to be updated automatically as stakeholders performs modifications on-the-go, allowing speedy and highly accurate design adjustments throughout the project. On this front, the Technology Acceptance Model (TAM) was adopted to determine the acceptance level of BIM-based VR technology in Malaysia. Data was acquired via a questionnaire survey, of which 92 out of 180 distributions were accepted for analysis, accounting to a respectable response rate of 51%. Consequentially, Principal Component Analysis result revealed that ‘Saving Cost and Resources’ is the most significant factor for BIM acceptance. Conversely, ‘Presence of Skill Gap’ was found to be the biggest stumbling block for BIM-based VR in cost estimation. Relationship analysis from the TAM also unveiled that the challenges of BIM-based VR did not produce mediating effect towards attitude and intention to use. This implies that the intention of construction professionals to adopt the technology wasn’t impeded by its challenges. Significantly, this study served as a benchmark in uncovering new possibilities of BIM and VR in project cost management, where the reliability and accuracy of conventional procurement can be enhanced with technology, particularly in BQ documentation, to fulfill the rising expectations of construction stakeholders across the globe.
A review of current diagnostic and treatment methods for key aldosterone-related diseases
Authors: Wang Sujuan , Zhao Qiaohui , Wang Tianyun
Published: October 2022

Aldosterone is a steroid hormone secreted from the adrenal cortex and metabolized primarily in the kidneys. It promotes sodium retention and potassium excretion. Most plasma aldosterone exists in free form, with a rapid turnover rate. The increased in aldosterone in the body may lead to various metabolic diseases, such as primary aldosteronism, diabetes, and chronic kidney disease. The clinical detection methods for aldosterone include radioimmunoassay, chemiluminescence immunoassay, and liquid chromatography tandem mass spectrometry (LC-MS/MS). In addition to addressing the issue of false negatives and false positives from cross-reaction in immunoassays, the advantages of high-throughput detection are reflected through the use of LC-MS/MS. Furthermore, there is also new progress in the development of a related mineralocorticoid receptor (MR) antagonist, from spironolactone to eplerenone, and to a third-generation MR antagonist, and finerenone, which has been approved by the United States Food and Drug Administration in 2021. The side effects of spironolactone and eplerenone can be overcome by finerenone, and the third-generation antagonist has shown significant effect in the treatment of chronic kidney disease associated with Type 2 diabetes. In this paper, aldosterone-related diseases, the clinical detection methods, and the corresponding treatment methods are discussed.
Klasifikasi Penjurusan pada Sekolah Menengah Atas (SMA) dengan Metode Algoritma C4.5
Authors: Eirlangga Yofhanda Septi , Syaputra Aldo Eko
Published: October 2022

Menteri Pendidikan indonesia telah menetapkan wajib belajar 12 tahun namun hanya pada saat Sekolah Menengah Atas (SMA) saja peserta didik baru bisa menentukan jurusan yang diminatinya. Disetiap tahun ajaran baru panitia PPDB (Penerimaan Peserta Didik Baru) mengalami kesulitan dalam menentukan jurusan dikarenakan penentuan jurusan masih dilakukan manual sehingga adanya ketidakcocokan dengan minat bakat peserta didik yang diakibatkan oleh human erorr. Maka perlu dilakukan sebuah penelitian dengan tujuan untuk membantu panitia PPDB dalam menentukan jurusan secara akurat dan efektif agar minat dan bakat peserta didik dapat tersalurkan dengan tepat. Oleh karena itu digunakanlah metode algoritma C4.5 yang merupakan salah satu algoritma data mining yang menghasilkan pohon keputusan (decision tree) yang cocok dalam pengklasifikasian data yang banyak. Data yang dipergunakan dalam penelitian ini diambil dari nilai rapor peserta didik kelas IX tahun 2022 sebanyak 44 data rapor yang memiliki 11 variabel nilai mata pelajaran yaitu IPA, IPS, Bahasa Indonesia, PKN, Pendidikan Agama Islam, MTK, bahasa inggris, BAM Seni Budaya, TIK dan Penjas. Hasil dari penelitian ini didapatkan pohon keputusan (decision tree) dengan 17 rule (knowledge) yang telah di cocokkan dengan data real dengan tingkat akurasi yang sangat tinggi. Sehingga menjadikan penelitian ini dapat membantu serta menjadi patokan bagi panitia PPDB dalam menentukan jurusan peserta didik baru setiap dimulainya ajaran baru di SMA pertiwi 2 Padang
Scientific study in the Loch Lomond and Trossachs area, Scotland
Authors: Adams C.E. , Smith R. , El Bestawy W. , Rodger J.R. , Honkanen H.M. , Maitland P.S. , White S.
Published: October 2022

The natural environment of the Loch Lomondside area, Scotland is exceptionally well-studied. Here we describe a project to catalogue publications that describe these studies, and to form a living database of references. We recorded 1,436 references from the mainstream scientific literature and reports from the “grey literature”. The taxonomic groups and habitats studied were highly skewed. Faunal studies were considerably commoner than those of flora; studies on vertebrate species were commoner than those on invertebrate species; fish and birds were more commonly studied than other vertebrate groups. Reports of studies on terrestrial ecosystems were more frequent than those on aquatic systems. Amongst freshwater species, some groups were very poorly represented (e.g. Rotifera, Hydracarina, Diptera, Nematoda, Microturbellaria and Tardigrada). Many studies have made very significant contributions to understanding the mechanisms that operate in the natural environment. The underlying reasons for the important contributions that the Loch Lomondside area has made to natural science are discussed.
Las One-stop-shops como modelo emergente en la gestión de la rehabilitación energética en España
Authors: Marmolejo-Duarte Carlos , Biere-Arenas Rolando , Spairani-Berrio Silvia , Crespo-Sánchez Eva
Published: October 2022

A pesar de las incontestables ventajas de la rehabilitación energética la tasa de renovación residencial es preocupantemente baja, en tanto las barreras para los hogares son infranqueables. Posiblemente se ha sobrevalorado la capacidad de éstos para emprender un proceso muy complejo que requiere conocimientos técnicos, financieros y de gestión. Así, recientemente han aparecido en la escena internacional One-Stop-Shops (OSS) para asistir de forma integral a la rehabilitación residencial. Este artículo estudia, mediante un análisis documental y entrevistas en profundidad, el panorama de las cuatro experiencias pioneras españolas. Los resultados destacan el importante papel que juegan las administraciones y los proyectos europeos como fuente de financiación y, sobre todo, de conocimiento específico; así como los obstáculos que se han superado para implementarlas y los de resolución pendiente. Estas iniciativas se vislumbran como instrumentos indispensables delante del arribo de los fondos Next Generation European Union (EU).
Weltsystem-Konzepte und die historische Erforschung des Indischen Ozeans
Authors: Nagel Jürgen G.
Published: October 2022

In seiner Weltsystemtheorie verfolgt Immanuel Wallerstein primär das Ziel, ein ganz bestimmtes Phänomen erklären: die Ungleichheit im modernen Kapitalismus. Letztendlich sucht er eine historische Erklärung für den heutigen Zustand der Weltwirtschaft. Um dies
zu tun, unternimmt Wallerstein zweierlei: Er entwickelt sowohl eine Wirtschaftstheorie als auch ein Raummodell. Einerseits beschreibt er einen globalen wirtschaftlichen Zusammenhang (Kapitalismus), geprägt durch die Distribution von Produktionsstätten und Plätzen der Kapitalakkumulation
sowie durch ungleichen Tausch. Andererseits modelliert er auf dieser Grundlage einen Raum bzw. ein System aus verschiedenen verbundenen Räumen. Letzteres ist eine Folge von Ersterem, aber auch ein Funktionselement dafür. Insofern gibt es bei Wallerstein einen untrennbaren Zusammenhang
von Wirtschaft und Raum.
Das ost-südostasiatische Weltsystem, seine Integration in das moderne Weltsystem und staatliche Transformation in China, ca. 1500 bis 1900
Authors: Kotik Tanja
Published: October 2022

Der vorliegende Artikel diskutiert und vergleicht verschiedene Ansätze der Weltsystemtheorie und beschäftigt sich mit der Diskussion um Ost-Südostasien als eigenständigem Weltsystem in der frühen und späten Neuzeit. Meine Grundannahme ist, dass sich China
bis ins 19. Jahrhundert hinein im Zentrum einer eigenständigen Weltwirtschaft in Ost- und Südostasien befand, welche auf der diplomatischen und wirtschaftlichen Ordnung des chinesischen Tributsystems basierte. Dabei gehe ich der Frage nach, wie sich der Zusammenstoß der ost-südostasiatischen
Region mit dem britisch dominierten, von Europa aus expandierenden kapitalistischen Weltsystem im 19. Jahrhundert auf die wirtschaftliche und staatliche Transformation Chinas auswirkte.
THE APPLICATION OF COOPERATIVE LEARNING MODEL OF TYPE STUDENT TEAM ACHIEVEMENT DIVISIONS (STAD) ON THE MATERIAL OF COMPOSING AN EQUIVALENT FORCE AT CLASS X TECHNIC OF BUILDING CONSTRUCTION SANITATION AND TREATMENT SMK NEGERI 1 PALANGKA RAYA
Authors: Shelin Suciana  , Yulin Patrisia
Published: October 2022

The research was motivated by the lack of student learning outcomes in the material of composing an equivalent force. Student who less actively involved in the learning process, learning group has not been managed well, the student who is good, medium and low receive equal treatment, not to be rewarded for the best student, good and lowest. The good student very extremely rare to help the weaker students. This research makes use of the quantitative method research and models of type STAD cooperative learning with population student of X technic of building construction sanitation and treatment as many as 28 people. Formulation of the problem in this study is how the application of models of type STAD cooperative learning can improve learning outcomes the material of composing an equivalent force and how the response of student in grade at class X technic of building construction sanitation and treatment SMK Negeri 1 Palangka Raya year 2017/2018. Succesful implementation of type STAD cooperative learning models in the material of composing an equivalent force is to know to an increase and decrease in class X technic of building construction sanitation and treatment of the prior action is pre-test to post-test. In the prior action, the student who can achieve the minimum of criteria competition (KKM) as many as 0 (0%) people with average value are 36.79. At LKS execution in a group, the student who is can achieve the minimum of competition as many as 28(100%) people with the average value is 75,34. At the postest after, students who are complete as many as 15(53.57%) with the average value is 59.88 and completeness level is 53.57%. In a totality value, the student who is complete as many as 15(53.57%) with average value is 65.37 and completeness classical is 53.57%. Although the thoroughness of student increased from the prior action to the finish value or after action, the classical or the overall student learning outcomes have not reached 85% KKM set at 70, on an individual basis there is some student who does not complete. Thus it can be retrieved the conclusion by the application of the model of type STAD cooperative learning can improve learning outcomes in class X technic of building construction sanitation and treatment SMK Negeri 1 Palangka Raya year 2017/2018
Flexural Modulus Enhancement and Minimization of Printing Time and Part Weight for PET-G, Using Taguchi-GRA-TOPSIS Techniques
Authors: N. Mohammed Raffic , K. Ganesh Babu , Saminathan Rajasekaran , Hadidi Haitham
Published: October 2022

Fused deposition modeling (FDM) is becoming the most promised additive manufacturing (AM) process in recent years due to the evident benefits, such as high design flexibility, low cost, friendly and economically use. The current study considers an optimization of four different FDM parameters varied in three levels, as layer thickness (0.17 mm, 0.25 mm and 0.33 mm), infill density (25, 50 and 75%), shell thickness (0.8 mm, 1.2 mm and 1.6 mm) and raster angle (0o, 30o and 60o) with an objective to reduce printing time, part weight and to enhance flexural modulus using Polyethylene Terepthalate - glycol modified (PET-G) material. Mono optimization of FDM input parameters has been done using signal to noise ratio method obtained from Taguchi�s L9Orthogonal Array (OA) and multi response optimization is applied through Grey Relational Analysis (GRA) and technique of order preference similar to ideal solution (TOPSIS) techniques. The response or its criteria weightages are calculated using Shanon�s entropy and CRITIC method which gives different weightages for the considered responses. Printing time ranks top with 37% from entropy method followed by flexural modulus with 36% and part weight ranks last with 28%. Flexural modulus ranks tops with 43% followed by part weight with 29% and printing time takes last position with 28% weightage.The ranking of alternatives from GRA- entropy and GRA- CRITIC methods are similar by recommending A1B1C1D1 (0.17 mm layer thickness, 25% infill density, 0.8 mm shell thickness and 0� raster angle) but TOPSIS-entropy and TOPSIS - CRITIC methods suggested different parameter combination A2B3C1D2 (0.25 mm layer thickness,75% infill density, 0.8 mm shell thickness and 30� raster angle). From all the four different methods adopted for optimization, the parameter setting obtained from level total suggests A2B1C1D2 (0.25 mm layer thickness, 25% infill density, 0.8mm shell thickness and 30� raster angle) and completely opposite to the ranking of alternatives. The carried - out confirmation trials carried out validated the optimized settings resulted from different methods. Infill density is found to be the most significant factor as compared to other input factors over the output assessed parameters.
Preliminary Technological and Environmental Considerations for Generating Mechanical Components using Plant-based UV Resin
Authors: Vasilescu Mircea Dorin
Published: October 2022

The scope of this paper is to determine the evolution of the dimensional value of the part and to study if there is gas and particle emission produced by the plant-based resin in the 3D printing process with mask stereolithography. For dimensional measurement, a solution with digital calliper is used. For the measurement of emission, two devices are used for indoor air quality. In the vertical direction of part body printed, it is possible to observe a descending linear type of direction with a minimum value at the highest element 3D printed. The data taken into account in this study are mathematically studied using the EXCEL regression equation for dimension. The gases emitted are measured with the booth devices in parallel for formaldehyde and volatile organic compound gases. For CO2 and particles, one of these devices is used. The air quality index was determined in relation to CO2 and, respectively, particle emitted. In the printing process, an increase in CO2 emission of 500 ppm can be observed in the initial phase of the process and a lower value in the body area. It is possible to consider that the quality air in 3D printing with plant-based clear resin is in the good to medium level from all types of emission. These data were put in ac-cordance with the level value offered by the manufacturer of the measuring devices. In this study the dimensional aspects are evaluated in parallel for two types of part bodies and the dimensional equations are the same after three mount times.
Analisis dan Perancangan Sistem Informasi Catatan Penjualan dan Inventori Berbasis Web
Authors: Darsono Ivan , Stefani Kezia
Published: October 2022

Proses dalam bisnis cukup beragam dan saling memiliki keterkaitan diantara satu dengan yang lain. Penulis merancang aplikasi inventori berbasis web untuk melacak stok barang masuk dan keluar dengan tambahan fitur pencatatan setiap transaksi yang sudah selesai dari platform e-commerce. Metode perancangan dalam penelitian ini menggunakan metode terstruktur. Penulis melakukan pembuatan Flow Map Diagram dan Data Flow Diagram.

Hasil dari penelitian ini berupa aplikasi yang mampu menambah stok barang, mencatat barang masuk dan keluar, mencatat penjualan, menambah jumlah admin, hingga menampilkan laporan stok, laporan barang masuk, laporan barang keluar, laporan penjualan, dan laporan detail barang. Melalui aplikasi ini dapat dicapai efisiensi dan kemudahan dalam memantau inventori beserta kemudahan saat mencatat transaksi yang telah selesai.
Perancangan Aplikasi Pencarian Rute Perjalanan Angkutan Kota (Angkot) di Kota bandung Berbasis Web Menggunakan Algoritma A*
Authors: Kristo Manuel , Shandi Yusup Jauhari
Published: October 2022

Transportasi dapat membuat perjalanan menjadi mudah, membuat bepergian dari satu tempat ke tempat lainnya menjadi semakin mudah dan cepat. Transportasi umum, salah satunya angkutan kota (Angkot) muncul sebagai solusi bagi masyarakat yang tidak memiliki kendaraan untuk bepergian serta membantu mengurangi beban kemacetan di perkotaan. Untuk menentukan rute yang terpendek dapat menggunakan algoritma A* (A star). Algoritma A* dapat membuat pencarian rute yang menjadi lebih optimal. Penelitian ini merancang aplikasi pencarian rute perjalanan angkutan kota (objek penelitian di kota Bandung) berbasis web dengan menggunakan Algoritma A*.
Biologic versus Synthetic Mesh for Ventral Hernia Repair: a protocol for systematic review and meta-analysis
Authors:   Department of Surgery, University of Miami, Miami, Florida, USA, Lyons Nicole , Siddiqui Ali , Anwoju Oluwatunmininu , Cohen Brianna , Ramsey Walter , O'Neil Christopher , Ali Zuhair , Liang Mike
Published: October 2022

Review question / Objective: To compare the clinical outcomes of utilizing biologic mesh versus synthetic mesh during ventral hernia repair (VHR). Eligibility criteria: Inclusion criteria were randomized controlled trials comparing biologic and synthetic mesh in ventral hernia repair. Studies were included if they were focused on adults (over age 18), human subjects, and were published in the English language. Studies were limited to only VHR and needed to compare biologic with synthetic mesh. Repair could be done open, laparoscopically, or robotically. Exclusion criteria included: (1) articles that only included synthetic or biologic mesh (ex. comparing two types of biologic mesh) or (2) procedures for other types of hernias, for example inguinal or hiatal.
To ban or not to ban. Analyzing the banning process of autonomous weapon systems
Authors: De Stercke Celien
Published: October 2022

Over the last decade, autonomous weapon systems (AWS), also known as ‘killer robots’, have been the subject of widespread debate. These systems impose various ethical, legal, and societal concerns with arguments both in favor and opposed to the weaponry. Consequently, an international policy debate arose out of an urge to ban these systems. AWS are widely discussed at the Human Rights Council debate, the United Nations General Assembly First Committee on Disarmament and International Security, and at gatherings of the Convention of Conventional Weapons (CCW), in particular the Expert Meetings on Lethal Autonomous Weapons Systems (LAWS). Early skepticism towards the use of AWS brought a potential ban to the forefront of policy making decisions with the support of a campaign to 'Stop Killer Robots' launched by the Human Rights Watch (HRW) in 2013. The movement is supported by Amnesty International, Pax Christi International, and the International Peace Bureau, among others. This campaign has catalyzed an international regulation process on the level of the United Nations (UN). Both a new protocol to the Convention on Conventional Weapons or a new international treaty have been considered. However, a lack of consensus stalls the process, and as such, leaves AWS in a regulatory gray zone.
Experiential Learning for Training Future Science Policy and Diplomacy Experts
Authors: Doole Fathima , Littin Shelley , Myers Samuel , Somasekhar Gowri , Steyaert Jennie , Lansey Kevin
Published: October 2022

Experiential Learning is a useful tool to prepare negotiators and politicians in the art of diplomacy and can have a unique value in Science Policy and Diplomacy training. This workshop review summarizes two EL activities undertaken in a University of Arizona SPD course. The first was a semester-long project in conjunction with graduate and undergraduate students from a UA climate change adaptation course and the United States Department of State’s Diplomacy Lab. For this project, students researched issues and potential policies to address climate change effects on water, energy, and food resources in the Lower Mekong river basin. The second activity was the Mercury Game, a negotiation simulation that challenged students to represent interests of various countries to tackle an international environmental issue. Student survey results and other feedback demonstrate that EL is a valuable tool for SPD education and preparation for practice. Insights into how faculty, staff and students can facilitate EL in coursework are also discussed. This paper is authored by the student participants and documents their outcomes and perceptions after completing these activities.
ARPA-H: Risky or Revolutionary? The Challenges and Opportunities of Biden’s New Biomedical Research Agency
Authors: Somani Soumya
Published: October 2022

The acceleration of COVID-19 testing platforms and vaccine development has demonstrated the possibility of expediting research for similar biomedical breakthroughs. However, the National Institutes of Health (NIH) lacks a framework to regularly sustain this type of research. A new federal agency, the Advanced Research Projects Agency for Health (ARPA-H), offers a unique opportunity to capitalize on the lessons learned from the COVID-19 pandemic and drive federal investment into high-risk, high-reward biomedical research. ARPA-H will mirror the flat bureaucratic structure of the successful Defense Advanced Research Projects Agency (DARPA) through the employment of independent project managers. ARPA-H is also unique in how it centers equity in the agency's core mission. These unique traits could enable the agency to fill the gaps in current biomedical research under the NIH. Nonetheless, ARPA-H’s implementation is not without challenges: its incorporation within the NIH has raised concerns regarding its ability to specialize in high-risk research and the diversion of funding away from the rest of the NIH. These worries can be mitigated through the separation of ARPA-H and the NIH. Successful implementation of the ARPA-H framework would supplement current NIH work, diversify the US federal research strategy, accelerate promising breakthroughs, promote equity in health, and transform the nature of biomedical research in the US.
Incentivizing Agrivoltaics to Improve Farmland Resiliency and Meet Renewable Energy Demands in Indiana
Authors: Taylor Audrey , Munsen Morgan
Published: October 2022

As Indiana looks to the future, it must balance the long-term success of its large agricultural sector with the need to increase renewable energy production and combat climate change. Often these goals seem to conflict with one another, but agrivoltaics – the dual use of land for active agricultural use and solar farming – is one technology uniquely situated to address these competing interests. However, current policies do not explicitly consider agrivoltaic systems and are ill-suited to spur further solar development in Indiana. Therefore, we propose amending Indiana Code § 6-1.1-8 to establish a preferential land use assessment program for a new “dual-use solar” land type code. Such a change would initiate investment in agrivoltaics technology and incentivize farmland preservation in the solar energy sector.
The Influence Of Local Content Towards The Sales Of SMEs Product Through Media Of Market Place
Authors: ASI Yuli Sintha , SUNDARI Ariefah , SUSANTO Hari
Published: October 2022

The transformation from traditional marketing into digital marketing brings changes to all aspects of human life, including economic aspects for  Micro, Small and Medium Enterprises. Local SMEs fail to compete because the product is not really well-known and is not marketed digitally. The digitalization era forced  SMEs to use social media for promotion. On the contrary, East Kotawaringin Regency SMEs are primarily unfamiliar with digital marketing. As a consequence, many SMEs are not able to survive. This research is carried out to help SMEs survive this Covid-19 disaster by implementing Digital Marketing to see how vital the SME sector is for regional income. It is a quantitative study to know the influence of selling products through the marketplace and how the local cultural content of the product influences the sales increase. The total population is 83  SMEs aged 18 to 25 years. The population is depreciated according to age, culinary sector and education. It obtained 31 samples. Questionnaires are distributed for data collection and are analyzed with SPSS 16. The finding of this research is that there is a correlation between local content in social media toward sales increase, as the independent shown by the t-count for each item is higher  < 0.05. SMEs promote their products on social media based on local culture content linked to a local government website or other businesses such as hotels and tourist attractions.
Study of the antioxidant and antidiabetic effect of ethanol and aqueous extracts of Anacyclus pyrethrum L. roots
Authors: NADIRA HAMDOUCHE , BENSLAMA Ouided , BENBOTT Amel , MOSBAH Camélia , DAOUI Haoua , CHBILLI Liela , Rabeh ARHAB
Published: October 2022

Anacyclus pyrethrum (L.) is a widely used plant in Algeria traditional medicine to treat painful diseases. The objective of this study was to evaluate the antioxidant and antidiabetic activities of the aqueous and ethanolic extract of the Anacyclus pyrethrum L. roots (AP) in Westar Albino rats. In vitro antioxidant activities of the extracts were determined by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method. The aqueous and ethanol root extract of Anacyclus pyrethrum at a concentration of 200 mg/kg was orally administered to streptozotocin induced diabetic rats. The phytochemical study showed that the extraction yield of ethanol and aqueous extracts was estimated at 10% and 9.3%, respectively. In addition, the study showed that the roots of AP are rich in phenolic and flavonoids compounds. Whereas, the ethanolic extract includes more polyphenol than the aqueous one (10.077 μgEAG/mg and 9.106 μg EAG/mg, respectively). The pharmacological study showed that both aqueous and ethanolic extracts had an antioxidant activity of 4.84 mg/mL and 5.71mg /mL, respectively. The short and medium-term of glucose tolerance tests showed a significant reduction effect on diabetic rats for the ethanolic extract. The results also showed a significant decrease in blood sugar (1.72g /L ± 2.23), cholesterol (0.58 g/L ± 0.47), triglycerides (0.39 g/L ± 0.47), uric acid (15.33 g/L ± 7.59), urea (0.68 g/L ± 0.80), TGP(165.33 U/L ± 39.85), and TGO enzymes (167.66 U/L± 41.14). The results of this study revealed that the extract of AP root possesses a reduction capacity of the proportion of blood sugar, which justifies its use in traditional medicine in the treatment of diabetes.
Serological Evidence of Herpes Simplex Virus-1 (HSV-1) Infection among Humans from Bandung, West Java Province, Indonesia
Authors: Hakim Dzulfikar Djalil Lukmanul , Gurnida Dida Akhmad , Nuraeny Nanan , Susilaningsih Fransisca Sri , Herawati Dewi Marhaeni Diah
Published: October 2022

BACKGROUND: Toxoplasma gondii, Rubella virus, Cytomegalovirus, and herpes simplex virus (TORCH) infection is still a significant burden in developing countries since they potentially increase perinatal death and decrease life quality by causing congenital disorders. As part of TORCH and as one of the most common infections in humans, HSV Type 1 infection also should receive attention. HSV-1 infection induces an immediate reactive oxygen species (ROS) production, indicate that ROS plays beneficial effects in several biological functions, including innate immunity and antiviral responses. HSV-1 preferentially replicate and establish latency in different subtypes of sensory neurons and in neurons of the autonomic nervous system that are highly responsive to stress hormones, including cortisol.

AIM: The objective of the study was to detect the latent HSV-1 infection in adults population and its effect on ROS and cortisol levels.

PATIENTS AND METHODS: Subjects were enrolled with consecutive-sampling methods among the adults population age 18–40 years old, with no health complaints. We collected their blood to examined IgG HSV-1, ROS, and cortisol levels.

RESULTS: A total of 57 subjects with 27 subjects were reactive IgG HSV-1 (herpes group) and 30 subjects were non-reactive IgG HSV-1 (non herpes groups). Mean of cortisol and ROS was 223.2904 nmol/L and 2.23337 IU/mL, respectively. There was a very weak correlation between HSV-1 infection with ROS and cortisol.

CONCLUSION: There is a positive effect of latent HSV-1 infection in the adult population on cortisol ROS levels.
Closure versus Non-closure Buccal Mucosal Graft Site for Lowering Post-operative Morbidity in Patient with Urethral Stricture Underwent Urethroplasty: A Systematic Review and Meta-analysis
Authors: Aulia Kindy , Irdam Gampo Alam
Published: October 2022

BACKGROUND: Buccal mucosal graft (BMG) has been a widely known technique for anterior urethral reconstruction; however, the studies regarding its morbidity are still limited.

AIM: The purpose of this study is to compare postoperative morbidity outcome between closure versus non-closure BMG harvest site in patients with urethral stricture underwent urethroplasty.

METHODS: A systematic review and meta-analysis of randomized controlled trials and prospective cohort studies was conducted. Literature searching was done through electronic databases, including PubMed, Science Direct, EBSCO, ProQuest, and Google Scholar. The inclusion criteria were men diagnosed with urethral stricture and underwent urethroplasty procedure. The participants were two groups of patients divided based on whether their BMG harvest site was closed or left open. No exclusion criteria applied to the types of participants. The statistical analysis was performed using Review Manager version 5.3 software. Cochrane risk-of-bias tool was used to evaluate the quality of the study.

RESULTS: We analyzed five studies qualitatively and three studies quantitatively. There was no significant difference between the closure and non-closure BMG in pooled standard mean difference (SMD) on the oral pain in day-1 and month-6 post-operation. However, pain score in day-1 post-operation was slightly higher in the closure group (SMD 0.49, 95% CI –0.31, 1.30). The incidence of perioral numbness in day-1 post-operation was significantly higher in the closure group (RR 1.48, 95% CI 1.04, 2.10, p < 0.05). The incidence of difficulty in opening mouth in day-1 post-operation also significantly higher in closure group (RR 1.48, 95% CI 1.14, 1.91, p = 0.003). There was no significant morbidity difference between two groups reported in five studies included after 6 months post-operation.

CONCLUSION: There was no significant difference between closure and non-closure of BMG in the post-operative pain morbidity. However, the incidence of the early perioral numbness and difficulty in mouth opening was significantly lower in non-closure group.
Accuracy of MRI CSF Flowmetry in the Diagnosis of Normal Pressure Hydrocephalus
Authors: Zakaria Hussein , Hafez Mohamed A. , Elsamman Amr K. , Amin Farid G. , Tarek Ayman
Published: October 2022

BACKGROUND: Normal pressure hydrocephalus (NPH) is one of the few treatable causes of dementia. NPH is diagnosed using the clinical triad of: Gait disturbance, progressive mental deterioration, urinary urgency, or incontinence in association with radiological findings suggestive of NPH, for example, ventriculomegaly, disproportionately enlarged subarachnoid space hydrocephalus, and narrow callosal angles.

AIM: The purpose of the present study was to assess the accuracy of MRI cine phase flow studies as a non-invasive modality in the diagnosis, and also for the prediction of improvement of symptoms suggestive of NPH without the need for CSF tapping.

METHODS: Twenty-six patients suffering clinically from the triad of NPH, or at least two of them; attending our neurology, psychiatry, and neurosurgery clinics in Cairo University Hospitals, with ages ranging between 50 and 85 years, randomly chosen regarding sex or other comorbidities. All patients underwent a regular MRI in addition to CSF flowmetry studies to correlate the MRI findings that reveal NPH with their known clinical features. Careful clinical assessment was performed to detect severity of symptoms, and patients were classified accordingly, and a disability score was provided. After CSF tapping, patients were reassessed clinically after 6–8 h to detect improvement of symptoms, and the degree of improvement was compared to the result of CSF flow study.

RESULTS: CSF flow studies, particularly stroke volume across the aqueduct of Sylvius, provide the highest significance in diagnosing hyperdynamic circulation evident by many radiological studies in cases of NPH. This was also found to be a good prognostic factor which correlates well with the improvement of symptoms following CSF tapping. However, its use to exclude suspicious cases of NPH seems unreliable, that is, not a good negative predictor. Findings of MRI CSF flow studies also show significance in detecting brain atrophic changes, especially peak systolic velocity, which usually accompany or mimic the clinical picture of NPH.

CONCLUSION: MRI CSF flow studies are an excellent aid as an adjuvant non-invasive technique in selection of suspicious cases as it shows significance in detecting hyperdynamic circulation, especially high stroke volume results in cases of NPH. Both CSF tapping and CSF flowmetry findings “low stroke volume values” were not found to be a good negative predictor for clinical improvement after shunting.
Le trajet de la sexuation, pourquoi et comment une identité sexuée ?
Authors: Neuburger Robert
Published: October 2022

Il est important pour chacun de se construire une identité sexuée, de se sentir exister comme homme ou femme ou autre dans son rapport à soi mais aussi reconnu, respecté, dans son rapport à l’autre ou aux autres, que ce soit dans la relation amoureuse, dans le couple, dans la famille, dans les groupes d’amis, au travail et, de façon générale, dans la société. Sont proposés six éléments essentiels qui « tressent » ce sentiment d’identité sexuée : éléments génétiques, éléments hormonaux, imitation et identification, attirances sexuelles, relations amoureuses, appartenance au groupe de pairs. Certaines défaillances lors de ce trajet et leurs conséquences sont évoquées.
Transitions de genre et psychanalyse : un nouage du réel au symbolique et à l’imaginaire
Authors: Fekete de Vàri François , Poncelet Margaux
Published: October 2022

Bénéficiant d’un intérêt médiatique et théorique sans précédent, la situation des personnes trans interpelle. L’apport des  gender studies  et des sciences humaines à la psychanalyse a conduit certains auteurs et praticiens à repenser l’assujettissement et la subjectivation à travers le genre, notamment pour ce qui concerne les parcours trans. Sans prétendre épuiser la question, cet article vise à apporter une contribution à la réflexion psychanalytique sur les transitions de genre ou de sexe à partir d’un nouage du réel au symbolique et à l’imaginaire. À cette fin, nous revenons d’abord sur certains éléments de définition des transitions. Ensuite, nous examinons la relecture de la théorie psychanalytique lacanienne par Judith Butler. Cette relecture permet, d’une part, d’envisager la constitution psychique du sujet en relation au contexte social dans lequel il s’inscrit et, d’autre part, de promouvoir la force subversive de l’imaginaire face au symbolique. Enfin, nous nous penchons sur l’instance du réel, définie comme l’insaisissable qui échappe à la symbolisation. Pensées à partir du réel, les situations trans sont alors réinscrites dans la dynamique d’invention du sujet aux prises avec sa jouissance.
La stérilisation volontaire à visée contraceptive comme facteur de transformation positive chez des femmes sans enfant
Authors: Ninane Nora , Mottrie Cindy , Colman Sarah , Duret Isabelle
Published: October 2022

En 2018, le Service de Gynécologie du CHU Saint-Pierre de Bruxelles a décidé d’ouvrir une consultation pour les femmes, sans enfant, en demande de stérilisation à visée contraceptive. Le nombre de ces demandes est en augmentation. Au moyen d’un canevas de questions semi-directives et des cartes Dixit comme « objet flottant », nous sommes allées à la rencontre de trois femmes sans enfant et stérilisées depuis six mois à un an et demi afin d’explorer les motivations et vécus à l’origine de leur choix. Les résultats mettent en évidence le poids d’événements historiques singuliers dans la décision d’inscrire corporellement leur non-maternité. Il semble que ces trois femmes se soient dirigées vers la stérilisation à un moment où elles ont eu besoin d’agir pour se réapproprier leur corps et leur vie, et de rétablir un vécu de sécurité suite à différents événements douloureux voire traumatiques. L’exploration de leurs parcours révèle que la stérilisation est l’aboutissement d’un cheminement mais aussi un processus de transformation d’une souffrance. Une fois stérilisées, elles rapportent ressentir un apaisement et un bien-être à la fois physique et psychologique, et évoquent l’émergence d’une vie différente et d’une identité plus alignée. Dans leurs histoires singulières, la stérilisation apparaît comme ayant eu un effet thérapeutique et libérateur.
Judiciariser le mariage
Authors: Monnot Aude-Cécile
Published: October 2022

Entre 1924 et 1935, le Code pénal soviétique condamne des pratiques matrimoniales, régulières dans le droit coutumier et musulman d’Asie centrale. La criminalisation de ces pratiques ouvre un conflit social d’ampleur opposant des acteurs aux visions incompatibles du droit et de la modernité et questionnant la légitimité de l’État à intervenir dans le champ matrimonial. À partir d’archives de procès, l’article analyse le processus de socialisation des justiciables à ce droit pénal. Informés par les dispositifs d’éducation populaire des juges et des activistes politiques, les justiciables contournent le droit pour échapper à la répression ; d’autres saisissent le juge pour s’opposer aux coutumes ou instrumentalisent le recours judiciaire afin d’asseoir leurs intérêts lors de transactions matrimoniales. Ce décalage entre le pays légal et le pays réel souligne la relative fluidité des pratiques judiciaires à l’échelle des cours locales. Les juges offrent alternativement une ressource aux justiciables ou s’illustrent par des décisions s’accommodant aux exigences déterminées par le politique.
Determinant factors for the strategic management of the supply chain of the Angolan cement industry
Authors: Campos Pedro , Pimentel Carina , Lopes José
Published: October 2022

Purpose: Cement is a priority consumer good in all modern societies. Considerable portions of the countries’ income are invested in construction and reconstruction of houses, shopping centers, schools, universities, research centers, pavements, bridges, dams, among other infrastructures. In view of its importance, it becomes relevant to understand the determinant factors for the strategic management of the cement supply chain (SC). The knowledge of these factors can support the development of management strategies that adequately orientate the operation of the cement industry and ensure an agile and/or efficient structure that facilitates the distribution of the products from this industrial sector.Methodology: This article presents the results of a qualitative research, based on semi-systematic literature review and interviews, which aimed to identify the determinant factors and barriers in the management of the SC of the Angolan cement industry (CI).Findings: This research made it possible to conclude that the determining factors are: cement production capacity and quality; supply levels and channels; infrastructure capacity and quality; capacity and quality of transport modes; existence of cement distribution strategies; collaboration, integration, agility, effectiveness and efficiency in the SC; availability of qualified labor; geographic location of markets; competitiveness factors (price, quality, response time, flexibility, agility, services, reliability, process variability and differentiation). Some barriers that undermine the supply of cement in the Angolan market have also been identified.Originality/value: Based on the literature review and the analysis of the interviews, we found that, in general, the strategic management of the SC of the CI depends on the level of development of the infrastructures, logistics, communication and the degree of collaboration and integration between the entities.
SPC-based model for evaluation of training processes in industrial context
Authors: Jesus Cristiano , Marcorin Adilson , Lima Rui M. , Sousa Rui M. , Souza Ingrid , Oliveira Eliana
Published: October 2022

Purpose: This article aims to present successful practices in the management of training processes based on virtual reality and augmented reality, namely a strategy for evaluating the process with the principle of continuous improvement in mind, and monitoring its performance in terms of productivity and waste levels. It is proposed to apply Statistical Process Control (SPC) tools to develop control charts for monitoring individual events (i-charts).Design/methodology/approach: The methodology is based on a case study developed in an industrial project and is guided by a literature review on Work-Based Learning (WBL) and SPC.Findings: The developed work shows that SPC tools are suitable for supporting decision making in situations where the data to be analyzed is generated by human-computer interactions, e.g., involving students and virtual learning environments.Originality/value: The innovative aspect presented in the article lies in the evaluation of the effectiveness of pedagogical resources arranged in simulation environments based on virtual and augmented reality. The accumulated knowledge about the application of SPC in service areas, and others that demand data analysis, reinforces the hypothesis of the suitability of its application in the case presented. This is an original application of SPC, normally used in business processes quality control, but which in this case is applied in an innovative way to the evaluation of industrial training processes, with the same spirit for which it was designed, i.e. to provide the means to manage the quality of a process.