bluuebunny/crossref_metadata_2025 huggingface dataset:
ФОРМУВАННЯ ФІНАНСОВОЇ СТРАТЕГІЇ В СИСТЕМІ ЗАБЕЗПЕЧЕННЯ КОНКУРЕНТОСПРОМОЖНОСТІ ПІДПРИЄМСТВА
Authors: Купира М.І.  , Киришко М.В.
Published: July 2020

У статті доведено, що формування фінансової стратегії як основи стійкого та конкурентоспроможного розвитку у довгостроковій перспективі вимагає чітко побудованого алгоритму з врахуванням сучасних тенденцій. Встановлено, що під фінансовою стратегією в системі забезпечення конкурентоспроможності підприємства важливо трактувати загальний план окреслення точковості фінансових цілей та завдань на довгострокову перспективу через формування фінансових ресурсів у векторному напрямку фінансовою стійкості.

Проведено теоретичний розбір сутнісного наповнення фінансової стратегії в процесі формування, реалізації та коригування з виділенням структурних елементів фінансової стратегії в частині результативності.

Розроблено архітектуру формування фінансової стратегії в системі забезпечення конкурентоспроможності через матричний аналіз та фінансовий ефект.

Доведено, що фінансова стратегія в частині результативності діє через принципи та етапність  щодо формування і впровадження та працює за виведеним алгоритмом: Управління = капітал + активи + інвестиції + грошові кошти+ прибуток + ризики. Узгодженість та ефективність управління  на кожному етапі створює вектор прибутковості в процесі гнучкої фінансової політики. В першу чергу, в систему закладають достатній обсяг фінансових ресурсів, методи ефективності використання капіталу, оптимізація його структури та швидке реагування й нейтралізація ризиків на довгострокову перспективу.

Запропоновано матрицю вибору фінансової стратегії в частині ефективного стратегічного управління підприємства через синергію та дисбаланс з визначеним рівнем ефективності кожного структурного елементу та розраховано фінансовий ефект від вбудованих  інноваційних інструментів у фінансову стратегію, який лише підсилить конкурентні позиції підприємства на ринку.

Фактично, фінансова стратегія є тією основою, яка забезпечує векторне фінансове підґрунтя для фінансово-економічного розвитку в частині нарощення прибутковості. Її ефективність окреслюється моментами, за яких стратегічні цілі ґрунтуються на реальних фінансових показниках та можливостях підприємства, чіткій системі управління, гнучкості та прозорості.
The Analysis of Behavior of Internet Users from the Perspective of Safety
Authors: Stefaniuk Tomasz
Published: July 2020

The Internet has become a ubiquitous medium that absorbs a greater proportion of our time. In addition to its unquestionable advantages, it presents a number of threats to the security of its users. The aim of the article is to analyse the ways in which individuals in different countries use the Internet and to examine the security implications resulting from the increasing popularity of the medium. The study demonstrates the results of a research conducted in the years 2018-2019 on a population of 562 Internet users from three countries: Spain, Poland and Turkey. The analysis of the results creates a gloomy picture of network users, who - despite risk awareness - do little to defend themselves against the threats until personally affected.
RESEARCHES AND PUBLICATIONS OF CUSTOMS BOOKS IN 2010–2019.
Authors: Razdorskii A. I.
Published: July 2020

The article presents a historiographic and bibliographic review of 70 studies and publications of customs books of the XVI – XVIII centuries, published in 2010–2019. Analyzed articles and monographs on the history of trade and customs of individual cities, prepared on the basis of materials from customs books, reviews of individual regional complexes and separate archival collections of these documents, studies on the source study of customs books, publication of texts of the sources under consideration.
KOMPARASI AKURASI METODE K-NEAREST NEIGHBOR DAN C4.5 UNTUK CUSTOMER RELATIONSHIP MANAGEMENT PADA PERUSAHAAN PEMBIAYAAN
Authors: Mohamad Anas Sobarnas  , Iskandar
Published: July 2020

Faktor utama pembiayaan bisnis adalah Layanan yang Mudah dan Cepat untuk pelanggan, Salah satu masalah perusahaan pembiayaan adalah kalah bersaing karena tidak adanya metode yang sistematis dalam menjaga hubungan yang baik dengan pelanggannya sehingga pelanggan tidak bertambah bahkan pelanggan lama pergi begitu saja. Salah satu metode dalam menjaga hubungan yang baik dengan pelanggan adalah dengan dibuatnya sistem komparasi untuk menguji tingkat keloyalan pelanggan, Sehingga pelanggan tetap loyal kepada Perusahaan. Adapun alat sebagai komparasi dalam aplikasi klasifikasi Pelanggan menggunakan algoritma Klasifikasi yaitu algoritma. K-Nearest Neighbor (K-NN) dan C4.5. Setelah dilakukan pengujian perbandingan kedua algoritma diatas ditemukan akurasi algoritma C4.5 sebesar 93.10% dan nilai akurasi model untuk algoritma KKN sebesar 90.52% dengan selisih akurasi 2,58%. Pengujian aplikasi berbasis web menggunakan bahasa program ASP.Net C # membandingkan hasil akurasi dari perbandingan kedua algoritma diatas maka algoritma (C4.5) adalah menghasilkan nilai yang terbaik, kemudian dilakukan pengujian data sampling keakuratan aplikasi dengan jumlah pengujian data 122 sample didapatkan hasil 109.8 sample akurat atau sebesar 92% dalam menentukan loyalitas klasifikasi pelanggan. Sehingga dengan adanya sistem aplikasi komparasi pelanggan berbasis web ini bisa menjadi alat bantu perusahaan dalam menguji loyalitas pelanggan pada perusahaan.
ANALISIS SIFAT FISIK TANAH DI DESA NDETU NDORA 1 KECAMATAN ENDE KABUPATEN ENDE
Authors: Rocky Sanggu Fransiskus
Published: July 2020

This study aims to determine the Physical Properties of Soil in Ndetu Ndora I Village, Ende District, Ende Regency. Research is exploratory research, by evaluating physical properties, evaluation results are described and compared with existing physical and chemical soil standards. The results showed that the texture of the soil consisted of clay and dusty clay. In structure, the type that exists is the structure of angular lumps, rounded lumps, granular, and crumbs. In soil, color is dominant by very dark brown, dark brown, very dark gray, very dark grayish brown. Soil consistency, it appears that these soils have a sticky, plastic, loose, softly consistence. The pH in the soil ranges from 4.8 to 6.4. And the slope is in the range of 13% - 23%.
AKTIVITAS FORMULASI PESTISIDA NABATI PADA SIPUT SETENGAH TELANJANG Parmarion martensi (GASTROPODA: ARIOPHANTIDAE)
Authors: Sunarti Una Sabina , Wahyuni Sri
Published: July 2020

This study aims to determine the activity of plant-based pesticide formulations on martyred Parmarion semi-naked snails. The study conducted at the Laboratory of the Faculty of Agriculture, University of Flores, Sam Ratulangi Street, Ende Regency. The research was conducted from February to August 2019 using a Completely Randomized Design (CRD) with two stages of treatment. The first stage was testing the contact poison activity in 5 treatments namely P0 = Control, P1 = Dilution 1: 5, P2 = Dilution 1:10, P3 = Dilution 1:15, P4 = Pure extract. The second step is to test the stomach poison with five treatments namely R0 = Control, R1 = No immersion, R2 = Soak 10 minutes, R3 = Soak 20 minutes, R4 = Soak 30 minutes. All treatments are repeated five times so that they will get 25 units of experiments in every treatment. The results showed the concentration of vegetable pesticide extracts in contact poisons and stomach poisons the highest average mortality for contact poisons were found in P4 therapy with the highest mortality value of 68.00% and experienced the fastest death above 50.00% at 50.80 hours with single speed time is 0.55 hours. While the stomach poison in the R4 treatment is 66.66% with the time, the fastest mortality is above 50.00%, which is 55.40 hours with a speed of 0.57 hours per individual.
KARAKTERISTIK SIFAT FISIK TANAH PADA LAHAN BUDIDAYA UBI KAYU (Manihot Esculenta Crantz) DI DESA WOLOGAI TENGAH
Authors: Umin Mariana , J.P. Anasaga Agustinus
Published: July 2020

Characteristics of soil physical properties are the diversity of soil conditions based on structure, texture, soil color, and soil moisture content. Features of the physical properties of the soil influenced by several factors, including poor land management, which results in a decrease in fertility levels that includes physical, chemical, and biological soil characteristics.The method used in this study is the sample cluster method. Consists of a small group of units and then randomly selected as a representative of the population, all elements in the chosen cluster used as research samples. This study aims to determine the physical characteristics of soil texture, soil structure, soil color, and soil moisture content in cassava (Manihot esculenta Crantz) in Wologai Tengah Village.The results showed that the texture of the soil in cassava soil dominated by clay texture. The structure of the angular lumpy ground, soil color 10 YR 2/1 Black, and 10 YR 2/2 Very Dark Brown and had a soil moisture content of 37.4%. This soil type is an ideal soil type or classified as fertile to cultivate cassava plants.
Leveraging glycomics data in glycoprotein 3D structure validation with Privateer
Authors: Bagdonas Haroldas , Ungar Daniel , Agirre Jon
Published: July 2020

The heterogeneity, mobility and complexity of glycans in glycoproteins have been, and currently remain, significant challenges in structural biology. Those aspects present unique problems to the two most prolific techniques: X-ray crystallography and cryo-electron microscopy. At the same time, advances in mass spectrometry have made it possible to get deeper insights on precisely the information that is most difficult to recover by structure solution methods: full-length glycan composition, including linkage details for the glycosidic bonds. These developments have given rise to glycomics. Thankfully, several large scale glycomics initiatives have stored results in publicly-available databases, some of which can be accessed through API interfaces. In the present work, we will describe how the Privateer carbohydrate structure validation software has been extended to harness results from glycomics projects, and its use to greatly improve the validation of 3D glycoprotein structures.
XEROPICTA (GASTROPODA, HYGROMIIDAE) GOES WEST: THE FIRST RECORD OF X. KRYNICKII (KRYNICKI, 1833) FOR MONTENEGRO, WITH A DESCRIPTION OF ITS SHELL AND GENITAL MORPHOLOGY, AND AN ADDITIONAL RECORD OF X. DERBENTINA (KRYNICKI, 1836) FOR ITALY
Authors: De Mattia Willy , Pešić Vladimir
Published: July 2020

Xeropicta krynickii (Krynicki, 1833) has a peri-Black Sea distribution, extending its range as far as Middle East. The species has never been recorded further West of Skopje (Macedonia). Recent collecting in Podgorica (Montenegro) revealed the presence of this taxon thus widening its range toward West, even if most probably the species has been introduced by human activities. Xeropicta derbentina (Krynicki, 1836) has been recorded from a single site in NE Italy. A second site has been recently discovered along a docking area of Trieste’s harbour (Italy).
MELANISM IN NATRIX NATRIX AND NATRIX TESSELLATA (SERPENTES: COLUBRIDAE) FROM MONTENEGRO
Authors: Gvozdenović Slađana , Schweiger Mario
Published: July 2020

This article present melanism in two species: Natrix natrix (Linnaeus, 1758) and Natrix tessellata (Laurenti, 1768) from Montenegro.
NEW SUBTERRANEAN FRESHWATER GASTROPODS OF MONTENEGRO
 (MOLLUSCA: GASTROPODA: HYDROBIIDAE), WITH DESCRIPTION OF ONE NEW GENUS AND TWO NEW SPECIES
Authors: Glöer Peter , Pešić Vladimir
Published: July 2020

Two new stygobiont species of the family Hydrobiidae Troschel, 1857, i.e. Iverakia hausdorfi n. gen. n. sp. and Bythiospeum demattiai n. sp. were described. The both species have been collected from the spring Iverak near Podgorica. Descriptions and photos of the holotypes are presented.
TWO NEW SPECIES OF THE GENUS BYTHINELLA MOQUIN-TANDON, 1856 (MOLLUSCA: GASTROPODA: HYDROBIIDAE) FROM THE WESTERN BALKAN PENINSULA)
Authors: Glöer Peter , Pešić Vladimir
Published: July 2020

Two new species of the genus Bythinella Moquin-Tandon, 1856, i.e. B. marici n. sp. from Bosnia and Hercegovina, and B. istoka n. sp. from Kosovo were described. The holotypes of both species as well as the penis morphology are depicted. In addition a list and distribution map of the Bythinella spp. occuring in the Western Balkan Peninsula is provided.
Politikai tartalmú büntetõeljárások a határõrségnél 1950-ben
Authors: Fórizs Sándor
Published: July 2020

The author provides archival documents on political trials involving the Border Guard Service in 1950.
Current status of dung beetles (Coleoptera, Scarabaeidae, Scarabaeinae) diversity and conservation in Natural Protected Areas in Chiapas (Mexico)
Authors: Sánchez-Hernández Gibrán , Gómez Benigno , Chamé-Vázquez Eduardo Rafael , Dávila-Sánchez Rolando A. , Rodríguez-López M. Edivaldo , Delgado Leonardo
Published: July 2020

Natural Protected Areas (NPAs) are consider adequate tools for biodiversity conservation. Currently in Mexico there are 182 federal NPAs classified according to their management objectives. Chiapas is the Mexican state with the highest number of decreed NPAs and also allocates one of the largest territorial extensions for its protection. Unlike other taxa, and despite their proven ability to respond to ecosystem changes, the study of dung beetles within Mexican NPAs has been underestimated, as they are not considered as a priority group within their management and conservation programs. Based on the review of information available in publications and database on dung beetles, a list of 112 species and seven subspecies recorded in 16 of the 19 federal NPAs established in Chiapas is presented. The species recorded by each NPA show a significant correlation with the number of publications, but a low percentage of them correspond to studies with systematic samplings and most of the species reported in several of the NPAs come from sporadic records, which prevents the study of several basic and applied aspects of dung beetles in the region. Therefore, studies that extensively analyze the communities of arthropod groups, such as the Scarabaeinae, are necessary to understand their response to changes in the ecosystem at local and regional scale. It is advisable that these insects be included in the previous justifying studies for the designation or establishment of NPAs and, in turn, considered in the biological monitoring programs of these areas for their capacity as a bioindicator group.
Effect of Different Gating Systems and Sand Mold Binder on the Cast-Quality of Bicycle Frame Produced through Sand Casting Method
Authors: Akhyar  , Husaini  , Ali Masri , Ali Nurdin , Ahmad Farhan
Published: July 2020

The bicycle frame produced through the metal casting process by recycling aluminum alloys can be an environmentally friendly alternative solution. Mold types and gating systems used generally affects the quality of the casting product. In this experiment, the effect of gating number and riser type variations (for sand binder) observed on casting defects, hardness, and impact value. Subsequently, chemical composition and microstructure of recycled aluminum metal from bicycle frames produced through sand mold casting are also evaluated. Three types of risers are bentonite, water glass, and furan resin. The results indicate that mold with two gating system has a low porosity as casting defects. The cast-bike frame produced using furan resin reaches the highest hardness value of 46 HRB compared to water glass and bentonite as the binder of sand-molds. The impact test observes 3.9 J carried out by the ASTM E23 sample at room temperature.
Influence of Forestry and Agriculture By-Products as Filler Materials on Thermal Conductivity of Fiberboard Panels Applied for Heat-Conditioned Building Partition Wall
Authors: Syuhada Ahmad , Machmud Muhammad Nizar
Published: July 2020

This paper presents a study on the thermal conductivity of fiberboards designed to find a proper board that would be applicable for heat-conditioned building walls. Fibers produced from forestry by-products processing, such as teak (tectona grandis), meranti ( HYPERLINK "https://id.wikipedia.org/w/index.phptitle=Shorea_acuminata&action=edit&redlink=1" \o "Shorea acuminata (halaman belum tersedia)" shorea acuminata), bayur (pterospermum javanicum) and also from agriculture by-products such as rice husk and rice bran, were then used as the materials prepared for the filler. Results showed that thermal conductivity of the board panel with such fibers were 0.0217 kW/m°C, 0.0330 kW/m°C, 0.0287 kW/m°C, 0.0253 kW/m°C and 0.0423 kW/m°C, respectively. Fiberboard panel with teak fiber as filler had the lowest thermal conductivity. It therefore could be used to significantly reduce the rate of heat transfer in such wall.
Self-Assembly Synthesis of ZIF-8/Polyvinylidene Fluoride(PVDF) Hybrid Membrane and its Pd (II)-Ion Extraction Behavior
Authors: Tong Fei , Gong Jie , Zhang Man Ying , Wang Yu Jie , Jiang Jin Long
Published: July 2020

Precious metal Pd are widely used in high-tech industries due to their scarcity and special properties. In this paper, 2-methylimidazole zinc salt (ZIF-8)/PVDF hybrid membrane was successfully synthesized by self-assemble method. The effect of polyarcylic acid sodium (PAAS) and polyethyleneimine (PEI) as complexing agents was investigated. The rejection rate of hybrid membrane under different polyelectrolyte-metal complexing ratios and their extraction performance under different concentration were examined.
Keratin/Egg White Blend Particles: Preparation and Characterization
Authors: Tanisood Suchai , Srihanam Prasong
Published: July 2020

The objectives of this work are to prepare keratin/egg white blend particles by emulsification solvent diffusion method and characterize their properties. The different factors including concentration, water: oil phases, spinning rate, and blending ratio were optimized. The morphological observation indicated that the shapes and sizes of particles were variable by the condition used. FTIR spectra indicated that all particles co-existed of α-helix and random coil structures. The decomposition rate of all particles found at least 4 steps and the blend particles have lower Td, max than the native protein particles. The obtained results were advantaged for the development of the keratin/egg white blend particles for specific applications such as drug-controlled release systems.
Flow Stress Behavior of Al-3.5Cu-1.0Li-0.4Mg-0.6Zn-0.3Ag Alloy under Hot Tension
Authors: Xiao Dai Hong , Liu Ning , Liu Wen Sheng
Published: July 2020

The hot deformation behavior and microstructure evolution of Al-3.5Cu-1.0Li-0.4Mg- 0.6Zn-0.3Ag aluminum lithium alloy were investigated by hot tensile tests on Gleeble-1500 thermal simulator at 480-510 °C and strain rates 0.0001-0.1 s-1. The results show that obvious flow steady-state phenomena occur during hot stretching and the main mechanism changes from dynamic recovery to dynamic recrystallization with the increase of temperature and decrease of strain rate. The constitutive equation was calculated using the true stress-strain curve obtained by the hyperbolic sinusoidal pair of deformation activation energy Q and temperature T proposed by Sellars and Tegart. The deformation heat activation energy is 226.783 KJ/mol.
Preparation of Melamine Formaldehyde Resin Modified with Pentaerythritol and its Flame Retardant Effect in Polypropylene
Authors: Zhou Fu Long , Wu Hong Zhi , Sun Ming Mei , Zhu Xin , Tang Lin Sheng
Published: July 2020

A new triazine charring agent, melamine formaldehyde resin modified with pentaerythritol (named as MF-MPOL), was synthesized through hydroxymethylation, condensation and etherification by using melamine, paraformaldehyde and pentaerythritol as raw materials, and characterized by solid-state 13C NMR and FT-IR. The intumescent flame retardant (IFR) consisting of MF-MPOL with ammonium polyphosphate has good flame retardancy in polypropylene (PP). The analysis of the residues obtained in cone calorimetry test showed that the IFR played a role of flame retardancy mainly in condensed phase. In other words, the porous and dense - continuous intumescent char layer formed during the burning process results in flame retardant effect by insulation of heat, oxygen and preventing the underlying PP from degradation and volatilization of pyrolytic products.
Effect of Cooling Methods on Microstructure and Mechanical Properties of Ti-3573 Alloy after Solution Treatment
Authors: Cai Yi Qin , Li Zhuang , Zhang Run Qi , Li Jin Yu , Wang Hao Xu , Cai Wen Hao , Zhang Li , Zhou Qi , Cui Xi Jun
Published: July 2020

In metastable beta Ti alloys, microstructural features can be varied over a wide range of length scales by changing different heat treatment parameters. Effect of cooling methods on microstructure and mechanical properties of Ti-3537 alloy after solution treatment was investigated. The result shows that with the decrease of cooling rate, the Vickers hardness of the alloy gradually increases. Among the three cooling methods of OQ, AC and FC, Ti-3573 alloy has the best shape and moderate yield strength, but tensile strength. The fractography of the β-substrate specimens showed that the fracture mode was ductile fracture. In the FC state, the α phase precipitates in a large amount in the Ti-3573 alloy, the yield strength and the tensile strength are greatly increased and the elongation is remarkably lowered. The tensile fracture shows a shallow fracture dip with low toughness.
An Engineering Correction Method for Buckling Load of Dense Stiffened Panels
Authors: Liu Wen Hao , Bai Rui Xiang , Su Kang , Zou Jian Chao , Liu Da , Lei Zhen Kun
Published: July 2020

It is convenient for designers to get the buckling loads of sparse stiffened panels quickly by using engineering calculation method to analyze the stability of composite stiffened panels, but it is still unable to meet the accuracy requirements of analysis of dense stiffened panels. The buckling loads of stiffened panels are closely related to the buckling modes. Based on capturing and analyzing the Compressive Buckling waveforms of T-shaped densely stiffened panels, this paper presents a formula for calculating the buckling loads according to the geometric coefficients. The results are very similar to those of finite element simulation, and can be used to calculate the buckling loads of sparse and dense stiffened panels with different stiffeners.
Preparation and Characterization of a Low Density and Low Pressure Sheet Molding Compound
Authors: Shi Min Xian , Dong Chuang , Zhang Yong , Huang Zhi Xiong
Published: July 2020

Low Density and Low Pressure Sheet Molding Compounds (LD-LPMC) were prepared by using magnesium oxide paste and crystalline polyester as thickening system to reduce molding pressure and Hollow Glass Microspheres (HGM) as fillers to reduce the density. The molding pressure of LD-LPMC was investigated. The effects of HGM content (0%, 3.8%, 7.6%, 11.4%, 15.2%, 19.0%) on the density, flexural strength and thermal conductivity of LD-LPMC were studied. The results showed that 2-4Mpa was the best molding pressure for the composite materials. With the increase of HGM content, the density, flexural strength and thermal conductivity of LD-LPMC decreased. The thermal conductivity increased with the increase of temperature. When the molding pressure was 3Mpa and the content of the HGM was 7.6%, the density decreased by 13.6%, the flexural strength only decreased by 23.3% and the thermal conductivity (40°C) also decreased by 11.5%, which reflected the low density, high strength and good thermal insulation performance of LD-LPMC.
Insight into cultural ecosystem services: comprehensive review through cluster analysis
Authors: Guruge T. P. S. R. , Jayasinghe-Mudalige U. K. , Udugama J. M. M. , Weerakoon D. , Premarathne S. P.
Published: July 2020

The nature of an ecosystem shapes human culture, heritage, values, social interactions and knowledge systems as well as amenity services (i.e. aesthetic, tourism and recreation, artistic, spiritual and intellectual development) considerably; thus, any changes in an ecosystem can have significant impacts on cultural services for societies. In light of this, this paper presents the outcome of a comprehensive review of literature focusing on the current status of cultural ecosystem services (CES) and the various conceptual, ideological and methodological approaches developed and used in this context. The literature on CES covering the 2009-2016 period was screened with the aid of a structured questionnaire which was developed, pre-rested and modified to fit the purpose. An Agglomerative Hierarchical Cluster Analysis characterised by Binary Squared Euclidian distance with Centroid Clustering method was employed to analyse the responses to the questionnaire, and the result was further supported and interpreted by way of qualitative discussion. The review, as a whole, identified the importance of CES and acknowledged its contribution to wellbeing as peripherals to a bundle of services. It recognised that most studies on this phenomenon were not limited to a specific region and/or on a specific system and were rarely quantified. Further, it was remarked that those studies did not value the ecosystems very often in monetary terms, but tended towards areas like mapping and cultural landscape.
Inflation targeting in Sri Lanka: the fiscal challenge
Authors: Abeygunawardana Kishan
Published: July 2020

No abstract available
The effectiveness of exchange rate channel of monetary policy transmission mechanism in Sri Lanka
Authors: Sandaroo N. D. V. , Mallikahewa S. N. K.
Published: July 2020

This study examines the effectiveness of the exchange rate channel in the transmission mechanism of monetary policy in Sri Lanka during the period from 1978 to 2015. A negative relationship between the two variables is accepted in theoretical insights on the topic. An increase in interest rate leads to appreciation of domestic currency against other foreign currencies. If the empirical situation is different to theoretical explanations, decision makers would not be able to make proper decisions to achieve macroeconomic targets in the economy. Monetary policy is conducted to achieve economic and price stability, and its policy shocks transforms to the economy through various transmission channels. A developing country like Sri Lanka usually prefers to depreciate local currency in order to increase export earnings and to reduce import expenditure to gain a balance of trade. Expansionary monetary policy tends to result in currency depreciation, thus increasing net exports. Higher economic growth can be achieved with domestic currency depreciation through increasing exports. In an inflationary situation, contractionary monetary policy can reduce aggregate demand with domestic currency appreciation. If there is no negative relationship between interest rate and exchange rate, the exchange rate transmission channel of monetary policy does not support the achievement of monetary policy co-objectives. The study uses the variables nominal exchange rate, Treasury bill rate, net exports and total external debt. Co-integration and Vector Error Correction tests are employed for the analysis due to the non-stationary of all the variables used in the study, and the results prove the negative relationship between exchange rate and interest rate as expected in the long run. Estimated value of the interest rate elasticity of exchange rate is -0.178, which proves that exchange rate channel is efficient in the Sri Lankan context. According to short run dynamics, 5% of the error in exchange rate is corrected annually.
Sri Lanka’s exports - out of sync with global demand
Authors: Abeysinghe Subhashini
Published: July 2020

A frequently cited reason for Sri Lanka’s weak export performance is the heavy concentration of its export earnings in a few products and a few markets. Hence diversifying the product and market portfolio has emerged as a key solution to the problem. This paper investigates the merit of this diagnosis and the proposed solution by analysing the concentration of products and markets of the Asian countries that are among the top 25 exporters in the world and that account for nearly 20% of world’s exports. The analysis finds that these countries demonstrate significantly high levels of concentration in a few markets and a few products in a manner similar to Sri Lanka. However, unlike in the case of Sri Lanka, the products and markets of the selected Asian countries demonstrate strong alignment with the trends in world market demand. Sri Lanka’s markets and products show significant deviation from global demand, and the data reveals this to be more pronounced in products than in markets. The findings infer that, contrary to the popular belief, concentration is not necessarily a hindrance to export success. It can even be considered a strength and not a weakness if its alignment with the emerging global demand patterns is robust. The insights drawn from the analysis highlight the limitations of the current approach to fixing the export problem of Sri Lanka and the importance of revisiting strategies proposed to fix the problem.
Why transport in Sri Lanka continues to go from bad to worse
Authors: Kumarage Amal S.
Published: July 2020

No abstract available
COX Inhibition Increases Alternaria-Induced Pulmonary Group 2 Innate Lymphoid Cell Responses and IL-33 Release in Mice
Authors: Zhou Weisong , Zhang Jian , Toki Shinji , Goleniewska Kasia , Norlander Allison E. , Newcomb Dawn C. , Wu Pingsheng , Boyd Kelli L. , Kita Hirohito , Peebles R. Stokes
Published: July 2020

The cyclooxygenase (COX) metabolic pathway regulates immune responses and inflammation. The effect of the COX pathway on innate pulmonary inflammation induced by protease-containing fungal allergens, such as Alternaria alternata, is not fully defined. In this study, we tested the hypothesis that COX inhibition augments Alternaria-induced pulmonary group 2 innate lymphoid cell (ILC2) responses and IL-33 release. Mice were treated with the COX inhibitors indomethacin, flurbiprofen, or vehicle and challenged intranasally with Alternaria extract for four consecutive days to induce innate lung inflammation. We found that indomethacin and flurbiprofen significantly increased the numbers of ILC2 and IL-5 and IL-13 expression by ILC2 in the lung. Indomethacin also increased ILC2 proliferation, the percentages of eosinophils, and mucus production in the lung. Both indomethacin and flurbiprofen augmented the release of IL-33 in bronchoalveolar lavage fluid after Alternaria challenge, suggesting that more IL-33 was available for ILC2 activation and that a COX product(s) inhibited IL-33 release. This is supported by the in vitro finding that the COX product PGE2 and the PGI2 analogs cicaprost decreased Alternaria extract–induced IL-33 release by human bronchial epithelial cells. Although contrasting effects of PGD2, PGE2, and PGI2 on ILC2 responses have been previously reported, the overall effect of the COX pathway on ILC2 function is inhibitory in Alternaria-induced innate airway inflammation.
Semantics of Saudi Political Discourse: A Significations Study of Prince Saud Al-Faicel Speeches
Authors: د. عبد اللطيف السلمي د. عبد اللطيف السلمي
Published: July 2020

the present study p urports to shed light on the problematics of the relationship between language and politics in general and on the semiotic formulation, in particular, of Prince Saud Al-Faicel political discourse. It attempts to explain how this discourse succeeded to formulate a political model capable, thanks to its argumentative and rhetorical tools, to decode or unlock regional crises and international transformations in order to make historical decisions. Such problematics reflect our particular perception of political discourse in its relationship with textual linguistics, along with the powerful semiotic discursive strategies and practices ever present in the analysis and interpretation of the political discourse of Prince Saud Al-Faicel. The Present study relied on an analytic frame following Norman Fairclough's model and other semiotic studies structured around lexicon and language construction. It also paid attention to analyzing the intricacies characterizing relations and strategies within power relations. The originality of the present study can be seen in its combination of the textual approach with the analytical one when dealing with political discourse.
The location of the visualization at the Diamond Record
Authors: د. إيناس محمود عبد الله أبو سالم د. إيناس محمود عبد الله أبو سالم
Published: July 2020

abu Muhammad al-Sijlmassi, who lived in Morocco in the late seventh Hijri century (7 AH), considered as one of the greatest pioneers Moroccan rhetorical school ,he was creative as he wrote his book tagged (The adorable Inclination in gendering methods of prose) In AH 704 / AD 1304. (The adorable Inclination) 'is an innovative and serious book in criticism and rhetoric from a philosophical and logical point of view, in which Al Sijilmassi employed the mind, taste and culture between Arabic and Greek in the critical and rhetorical lesson, and came up with a new approach that is more understanding of Aristotelian theories in criticism and rhetoric. The aim of this study was to show the distinctive features of the book of the Inclination through a review of the most important of the topics classified by Al Sijlmassi under the science of the rhetoric - especially mentioning those related to poetry and capillarity and the main elements that Al Sijlmassi sees are the real components the capillarity of poetry and art and it`s beauty, where this was a reality In a type of (imagination) more than all other types, and therefore our study came to the gender of imagination more detailed and broaden than the rest of the genders of the book; because imagination is the subject of poetic formation, and this is field of our study. We did not forget to also observe any other species that may be a catalyst in the formation of poetry, occurred in a section other than the section of imagination, so the methodology of this study began with a quick view of the era of Al Sijlmassi and a brief on his biography, and his thought about the development of rhetoric in his time. Then we presented in the second section some of the features of the book and the new of Al Sijlmassi, which distinguish him, before we get to the third section, as soon as we enter it we get in his world and we begin our tour in it and what he inundates about the subject of imagination, which is our main subject of this study. It was found through the brief research that Al Sijlmassi is a pioneer in the field of criticism, rhetoric and literary theorem, resulted from the deep thought and deepening of the culture of both Arabic and Greek, as we have seen his progress in his vision of poetry and capillarity components, and the importance of providing imagination before anything else, so that poetry to be a Complete and vibrant living being. As we conclude from our study of the types of rhetoric Al Sijlmassi has, he monitored a lot of important pillars that revives the words and sentences and versification and transmit poetic blood in it, and thus create to the recipient pleasure, emotion and provocation. Finally, we hope that we have succeeded as much as our humble effort in going through a giant book!
The effect of meaning and performance on the linguistic sound distance of time The response to Dr. Ahmed Keshk in his research tagged of linguistic voice functions as a model Semantic Critical Voice Study
Authors: د. زمزم أحمد علي تقي د. زمزم أحمد علي تقي
Published: July 2020

the distance of time it takes to pronounce the linguistic sound within its context is determined by a number of things, including the location of the sound and the method of performance that depends on the style, purpose and meaning, the meaning focuses with the pronunciation and linguistic sound; To form systems with time distances in performance, which is the focus of the research that we are blocking now, and these distances are those that control the syllables and thus control the tone, they are performed based on the meaning and were chosen to establish the effect of the meaning and performance on the distance of the linguistic sound time a study by the researcher Dr. Ahmed Keshk Title of Linguistic Voice Jobs; An Attempt to Understanding Morphological and PhoneticIn it, he discussed the complete anagrams and disagreed with the rhetoric about it, and tried to prove his absence, but he analyzed many verses that contain a cross-sectional analysis of linguistic sound only without taking into account the meaning and art of performance and the resulting time distances for sound and this is what this study will include
Relationship between plasma phosphatases activities; histopathological indicators of brain injury and malondialdehyde levels in Pb and Ca exposed-rat
Authors: Fadairo Ekaette Akpan , Otite-Douglas Mfon Isuaikoh
Published: July 2020

No Abstract.
Letramentos a distância na (e na pós) pandemia
Authors: Pinheiro Petrilson
Published: July 2020

Neste ensaio, discuto a questão dos letramentos no contexto atual de pandemia de Covid-19, a fim de repensar a educação, em particular a educação básica, através de uma reflexão que envolve revisitar o passado, analisar criticamente o presente para, então, imaginar o futuro. Faço um exercício crítico dialético, em que as ideias se desenvolvem a partir de teses, antíteses e sínteses, de uma forma ambivalente, procurando ver tensões, contradições e diálogos comuns, sem endeusar ou demonizar possibilidades. Concluo que é preciso estabelecer diretrizes aos professores que sejam factíveis e flexíveis, sobretudo em relação à infraestrutura tecnológica mínima e às condições de trabalho dos docentes, respeitando a realidade de cada contexto e as propostas pedagógicas de cada escola. Neste momento, é fundamental também que as escolas e os professores considerem a diversidade de estudantes atendidos, buscando verificar que recursos os alunos efetivamente têm para propiciar oportunidades de aprendizagem a todos.
Разрешение споров, связанных с защитой права собственности, в делах о банкротстве
Authors: Гвоздев Ю.Г.
Published: July 2020

СТАТЬЯ ПОСВЯЩЕНА АНАЛИЗУ ПРОБЛЕМНЫХ ВОПРОСОВ, СВЯЗАННЫХ С ЗАЩИ- ТОЙ ПРАВА СОБСТВЕННОСТИ И ПРЕДОСТАВЛЕНИЕМ ВЛАДЕЛЬЧЕСКОЙ ЗАЩИТЫ ПРИ РАССМОТРЕНИИ ОБОСОБЛЕННЫХ СПОРОВ ОБ ИСКЛЮЧЕНИИ ИМУЩЕСТВА ИЗ КОНКУРСНОЙ МАССЫ В ДЕЛАХ О БАНКРОТСТВЕ. АВТОРОМ ТАКЖЕ ПРИВЕДЕН КРАТКИЙ ОБЗОР СУДЕБНОЙ ПРАКТИКИ ПО ЗАТРОНУТОЙ ТЕМЕ.
Субординация кредиторских требований, возникших после возбуждения производства по делу о банкротстве: возможные правоприменительные модели de lege lata
Authors: Галкин С.С.
Published: July 2020

СТАТЬЯ ПОСВЯЩЕНА ИССЛЕДОВАНИЮ ПРАКТИЧЕСКИХ АСПЕКТОВ СУБОРДИНАЦИИ КРЕДИТОРСКИХ ТРЕБОВАНИЙ КОНТРОЛИРУЮЩИХ И АФФИЛИРОВАННЫХ С ДОЛЖ- НИКОМ ЛИЦ, КОТОРЫЕ ВОЗНИКЛИ ПОСЛЕ ВОЗБУЖДЕНИЯ ДЕЛА О БАНКРОТСТВЕ. ПРАВОВАЯ ПРОБЛЕМА ПОНИЖЕНИЯ В ОЧЕРЕДНОСТИ УКАЗАННЫХ ТРЕБОВАНИЙ ИС- СЛЕДУЕТСЯ В РАБОТЕ С УЧЕТОМ МАТЕРИАЛЬНО-ПРАВОВОЙ И ПРОЦЕССУАЛЬНОЙ СОСТАВЛЯЮЩИХ. НА ОСНОВЕ АНАЛИЗА ОСОБЕННОСТЕЙ И ТЕНДЕНЦИЙ РАЗВИТИЯ ИНСТИТУТА СУБОРДИНАЦИИ КРЕДИТОРСКИХ ТРЕБОВАНИЙ В ОТЕЧЕСТВЕННОМ ПРА- ВОПОРЯДКЕ АВТОР ФОРМУЛИРУЕТ ВОЗМОЖНЫЕ МОДЕЛИ ПРАВОПРИМЕНИТЕЛЬ- НЫХ РЕШЕНИЙ ПО КВАЛИФИКАЦИИ ТРЕБОВАНИЯ СВЯЗАННОГО С ДОЛЖНИКОМ ЛИЦА КАК ТЕКУЩЕГО ЛИБО ПОДЛЕЖАЩЕГО УДОВЛЕТВОРЕНИЮ В ОЧЕРЕДНОСТИ, ПРЕДШЕСТВУЮЩЕЙ РАСПРЕДЕЛЕНИЮ ЛИКВИДАЦИОННОЙ КВОТЫ.
Способы защиты кредитора по мировому соглашению
Authors: Берлин А.Я.
Published: July 2020

СТАТЬЯ ПОСВЯЩЕНА ИССЛЕДОВАНИЮ СРЕДСТВ ПРАВОВОЙ ЗАЩИТЫ, ДОСТУПНЫХ СТОРОНАМ МИРОВОГО СОГЛАШЕНИЯ В СЛУЧАЕ ЕГО НЕИСПОЛНЕНИЯ. ОТМЕЧАЕТ- СЯ ШИРОКОЕ РАСПРОСТРАНЕНИЕ ИНСТИТУТА ИЗМЕНЕНИЯ ПОРЯДКА И СПОСОБА ИСПОЛНЕНИЯ СУДЕБНОГО АКТА ПРИ ОГРАНИЧЕНИИ ИСКОВОЙ ФОРМЫ ЗАЩИТЫ. СЛОЖИВШИЙСЯ ПОДХОД НЕ СООТВЕТСТВУЕТ НАЗНАЧЕНИЮ ИСКОВОГО ПРОИЗ- ВОДСТВА КАК УНИВЕРСАЛЬНОЙ ФОРМЫ РАЗРЕШЕНИЯ СПОРА О ПРАВЕ ГРАЖДАН- СКОМ, ОДНАКО ОБУСЛОВЛЕН ПРОБЕЛАМИ ПРОЦЕССУАЛЬНОГО РЕГУЛИРОВАНИЯ, НЕОБХОДИМОСТЬ УСТРАНЕНИЯ КОТОРЫХ ОБОСНОВАНА СОВРЕМЕННОЙ ДОКТРИ- НОЙ ГРАЖДАНСКОГО ПРОЦЕССА.
Нужны ли вещному праву вещные права?
Authors: Алексеев В.А.
Published: July 2020

СТАТЬЯ СОДЕРЖИТ КРИТИЧЕСКИЙ АНАЛИЗ ПРОЕКТА № 47538-6/5 ФЕДЕРАЛЬНО- ГО ЗАКОНА «О ВНЕСЕНИИ ИЗМЕНЕНИЙ В ЧАСТЬ ПЕРВУЮ ГРАЖДАНСКОГО КОДЕК- СА РОССИЙСКОЙ ФЕДЕРАЦИИ», ВЫНЕСЕННОГО НА ОБСУЖДЕНИЕ СОВЕТОМ ПРИ ПРЕЗИДЕНТЕ РФ ПО КОДИФИКАЦИИ И СОВЕРШЕНСТВОВАНИЮ ГРАЖДАНСКОГО ЗАКОНОДАТЕЛЬСТВА. АВТОР ПРИХОДИТ К ВЫВОДУ О ТОМ, ЧТО КОНЦЕПЦИЯ ПРО- ЕКТА НЕ ОТВЕЧАЕТ СОВРЕМЕННЫМ ПОТРЕБНОСТЯМ ПРАВОВОГО РЕГУЛИРОВАНИЯ ГРАЖДАНСКОГО ОБОРОТА И ПРЕДСТАВЛЯЕТ СОБОЙ НЕПОДГОТОВЛЕННЫЙ ПРАВО- ВОЙ И СОЦИАЛЬНЫЙ ЭКСПЕРИМЕНТ. В КАЧЕСТВЕ АЛЬТЕРНАТИВЫ ЗАМКНУТОМУ ПЕРЕЧНЮ ОГРАНИЧЕННЫХ ВЕЩНЫХ ПРАВ ПРЕДЛАГАЕТСЯ ИЗЪЯТИЕ ИЗ ЗАКОНА ПОНЯТИЯ СУБЪЕКТИВНОГО ВЕЩНОГО ПРАВА И ИСПОЛЬЗОВАНИЕ КОНЦЕПЦИИ ДЕЙСТВУЮЩЕГО ГК РФ, КОТОРЫЙ УСТАНАВЛИВАЕТ ДЛЯ РЯДА ПРАВ, НЕЗАВИСИ- МО ОТ ОТНЕСЕНИЯ ИХ К ВЕЩНЫМ, ОСОБЫЙ ПРАВОВОЙ РЕЖИМ, ОСНОВОЙ КОТО- РОГО ЯВЛЯЕТСЯ ПРИДАНИЕ ЭТИМ ПРАВАМ СВОЙСТВА СЛЕДОВАНИЯ.
Ограничение вещных прав в общих интересах: европейский опыт
Authors: Богатина Ю.Г.
Published: July 2020

В ДАННОЙ СТАТЬЕ ПОЙДЕТ РЕЧЬ О КРИТЕРИЯХ, КОТОРЫЕ ИСПОЛЬЗУЮТСЯ ПРИ ОЦЕНКЕ ПРАВОМЕРНОСТИ ДЕЙСТВИЙ ГОСУДАРСТВА, ОГРАНИЧИВАЮЩИХ ПРАВО ЧАСТНОЙ СОБСТВЕННОСТИ, И О ПОСЛЕДСТВИЯХ ТАКИХ ДЕЙСТВИЙ. ПРЕДЛА- ГАЮТСЯ К ОБСУЖДЕНИЮ ВОПРОСЫ О ТОМ, ЧТО ПРЕДСТАВЛЯЕТ СОБОЙ ОБЩЕ- СТВЕННЫЙ ИНТЕРЕС И В КАКИХ СЛУЧАЯХ ВМЕШАТЕЛЬСТВО ВЛАСТЕЙ ЯВЛЯЕТСЯ ДОПУСТИМЫМ, КАКАЯ КОМПЕНСАЦИЯ ДОЛЖНА ВЫПЛАЧИВАТЬСЯ СОБСТВЕННИ- КУ ЗА ОГРАНИЧЕНИЕ ЕГО ПРАВА И ВСЕГДА ЛИ ОТСУТСТВИЕ ВОЗМЕЩЕНИЯ СО СТОРОНЫ ГОСУДАРСТВА ЯВЛЯЕТСЯ НАРУШЕНИЕМ МЕЖДУНАРОДНЫХ СТАНДАР- ТОВ ЗАЩИТЫ ВЕЩНЫХ ПРАВ.
San Juan de Ávila, doctor de la misericordia
Authors: Martínez Rojas Francisco Juan
Published: July 2020

El Jubileo Extraordinario de la Misericordia ha sido un importante acontecimiento eclesial, que ha permitido profundizar en esta realidad que el Papa Francisco define como “la viga maestra que sostiene la vida de la Iglesia” (Misericordiae vultus 10). En la historia de la Iglesia, los santos han vivido la experiencia de la misericordia de Dios de diversas maneras, y como vivencia personal la han reflejado en sus escritos. Es el caso de San Juan de Ávila, quien trató abundantemente sobre la misericordia tanto en sus obras impresas como en su epistolario y en sus predicaciones. El presente artículo pretende resumir la riqueza del magisterio del Apóstol de Andalucía sobre la misericordia.
Un intento frustrado de fundación del Oratorio de San Felipe Neri en Écija (1749) Universidad de Sevilla
Authors: Jordán Fernández Jorge Alberto
Published: July 2020

En este artículo se analiza un expediente conservado en el Archivo General del Arzobispado de Sevilla que trata acerca del intento de fundar una nueva congregación del Oratorio de San Felipe Neri en la ciudad de Écija (Sevilla) el año 1749, fundación que finalmente no se llevó a cabo.
Sobre la construcción y restauración de la iglesia sevillana de San Bartolomé y su torre
Authors: Higuera Meléndez José Manuel
Published: July 2020

Tras décadas de deterioro de sus elementos exteriores, el sevillano templo de San Bartolomé ha visto por fin iniciada la restauración del más significativo de ellos, que no es otro que su esbelta e inacabada torre. Sobre la singular atalaya, compuesta en la actualidad sólo por fuste y cuerpo de campanas, se acometerán en una primera fase labores de consolidación estructural y de recuperación de sus revestimientos, estando prevista posteriormente la reposición del remate perdido a mediados del siglo pasado. Dicho remate sería, según la memoria del proyecto de restauración, el originalmente proyectado para coronar la torre. Sin embargo, tanto el análisis del proceso constructivo del templo como el conocimiento de la arquitectura diocesana de la época, aspectos que desarrolla el presente artículo, así como algún testimonio gráfico coetáneo, llevan a datarlo indefectiblemente en una fecha muy posterior. El debate, pues, está servido.
La reutilización lúdica del espacio urbano en tiempos de la COVID-19
Authors: Sánchez García Raúl
Published: July 2020

El presente artículo forma parte de la sección de debate "Deporte y COVID-19" del Volumen 1, Número 1, de Sociología del Deporte (SD).
So sánh tỉ lệ trẻ sinh sống giữa chuyển phôi phân chia với phôi nén tại thời điểm 66 ± 2 giờ sau ICSI sử dụng hệ môi trường nuôi cấy đơn bước ở bệnh nhân TTTON
Authors: Luu Thi Minh Tam , Tran Thi Thuy An , Nguyen Ngoc Quynh , Tran Tu Cam , Pham Duong Toan , Huynh Gia Bao , Ho Manh Tuong
Published: July 2020

Mục tiêu: So sánh các kết quả lâm sàng của việc chuyển phôi ngày 3 hoặc ở giai đoạn phân chia hoặc có dấu hiệu nén sớm khi được nuôi cấy trong môi trường nuôi cấy đơn bước (SSM).

Phương pháp: Đoàn hệ tiến cứu được thực hiện tại IVFMD, Bệnh viện Mỹ Đức. Tiêu chuẩn nhận: phụ nữ trải qua chu kỳ điều trị IVF/ICSI thoả (i) ≤2 chu kỳ điều trị, (ii) kích thích buồng trứng bằng GnRH antagonist (iii) phôi được nuôi cấy trong môi trường đơn bước (Life Global®) và (iv) đồng ý chuyển 2 phôi hoặc ở giai đoạn nén sớm hoặc giai đoạn phân cắt, có 7-9 tế bào, phân mảnh ≤20%. Kết cục chính là tỷ lệ trẻ sinh sống. Kết cục phụ là các tỷ lệ: thai lâm sàng, làm tổ, thai diễn tiến, thai ngoài tử cung và sẩy thai.

Kết quả: Từ tháng 12/2016 đến tháng 4/2018, có 430 bệnh nhân được nhận, tương ứng 215 bệnh nhân mỗi nhóm. Độ tuổi trung bình ở nhóm được chuyển phôi nén sớm nhỏ hơn đáng kể so với nhóm được chuyển phôi phân chia (32,7 ± 4,5 so với 33,7 ± 4,7 tuổi; P = 0,03). Hiệu chỉnh (OR) tỷ lệ trẻ sinh sống khi chuyển phôi nén sớm so với phôi phân chia vào ngày 3 sau chu kỳ chuyển phôi đầu tiên là 1,02 (95% [CI] 0,69-1,51) và 0,9 (95% CI 0,57-1,41). Tỷ lệ trẻ sinh sống lần lượt là 32,6% và 33,0%. Các kết cục phụ khác không có khác biệt thống kê giữa hai nhóm.

Kết luận: Chuyển hai phôi ngày 3 hoặc giai đoạn phân chia hoặc có dấu hiệu nén sớm cho kết cục thai kì giống nhau khi được nuôi cấy trong SSM.
Nghiên cứu một số chỉ số siêu âm của thai từ 11 tuần đến 13 tuần 06 ngày
Authors: Nguyen Hai Long , Tran Danh Cuong , Bui Hai Nam , Tran Viet Hoa
Published: July 2020

Mục tiêu: Nghiên cứu các giá trị BPD, HC, AC, FL và mối liên quan với CRL để ứng dụng vào chẩn đoán tuổi thai và chẩn đoán sớm các bất thường thai nhi. Phương pháp nghiên cứu: Thực hiện trên 450 thai phụ mang đơn thai có tuổi thai từ 11 tuần đến 13 tuần 06 ngày. Loại trừ những trường hợp bất thường sớm hình thái thai nhi. Đo các chỉ số CRL, BPD, HC, AC, FL. Mỗi chỉ số được đo hai lần lấy giá trị trung bình. Chúng tôi tính giá trị trung bình của các chỉ số nói trên, mối tương quan tuyến tính của chúng với CRL. Tính chỉ số BPD/CRL, HC/CRL, AC/CRL và FL/CRL. Kết quả: Giá trị trung bình của CRL là: 60,55±7,82mm, của BPD là 21,69±2,54mm, của HC là: 78,46±8,75mm, của AC là: 64,66±7,84mm của FL Ià 7,71±2,14mm. Phương trình tuyến tính BPD=CRLx0,223+8,007 với R2=0,567 và p
Đặc điểm đột biến gen Globin của những đối tượng nguy cơ cao sinh con mắc Thalassemia tại Trung tâm chẩn đoán trước sinh Bệnh viện Phụ Sản Trung ương năm 2018
Authors: Nguyen Thi Van Anh , Hoang Thi Ngoc Lan , Vu Huong Ly , Le Phuong Thao , Tran Danh Cuong
Published: July 2020

Mục tiêu: Mô tả tỉ lệ các đột biến gen α-globin và β-globin hay gặp. Đối tượng và phương pháp nghiên cứu: 318 đối tượng có nguy cơ cao mang đột biến trên gen α-globin và β-globin. Các đối tượng được lấy máu và chẩn đoán tìm đột biến nhằm phát hiện các dạng đột biến gen Thalassemia bằng kỹ thuật lai phân tử ngược trên màng và trên thanh lai Strip Assay tại Trung tâm Chẩn đoán trước sinh, Bệnh viện Phụ Sản Trung ương năm 2018. Kết quả: 270/318 trường hợp mang gen đột biến chiếm 85%. Trong đó, có 161/270 người đột biến mang 1 đột biến α-thalassemia (60%), 66/270 người mang 1 đột biến β-thalassemia (24%) và 43/270 ngươi mang đồng thời 2 đột biến ở trạng thái dị hợp tử kép (16%). Đặc biệt có 2 trường hợp mang đòng thời 3 đột biến: --SEA/-α4.2/βE và -α3.7/βCd17/βE. Đột biến --SEA trên gen α-globin chiếm tỉ lệ cao, xuất hiện ở 151/161 trường hợp (93,8%>). Các đột biến β-globin hay gặp là HETCd26 (36,5%,), HOM Cd26 (6%), Cd41/42 (25,8%), Cd17 (21,2%), Cd71/72 (6%>), IVS 1.1 (3%>) và Cd95 (1,5%). Kết luận: Tỉ lệ cao đột biến α° và β° trong cộng đồng, khuyến cáo thực hiện sàng lọc bệnh Thalassemia cho tất cả thai phụ trong 3 tháng đầu và tư vấn chẩn đoán trước sinh cho các đối tượng được xác định là người mang đột biến globin.