bluuebunny/crossref_metadata_2025 huggingface dataset:
ASYMPTOTIC SOLUTIONS OF A TWO-POINT EDGE-BASED PROBLEM FOR A LINEAR SINGULARLY DISTURBED SYSTEM OF DIFFERENTIAL EQUATIONS IN NONCRITICAL AND CRITICAL STABLE CASES
Authors: Pafyk S.
Published: March 2020

Using asymptotic methods in the theory of differential equations and their systems, an asymptotic solution of the boundary value problem for a linear singularly perturbed system of differential equations is constructed. Considered non-critical and critical resistant cases. For each of the cases, the corresponding asymptotic estimates were found.
LEGAL REGULATION OF UNIVERSAL JURISDICTION IN NATIONAL LEGISLATION: A COMPARATIVE ASPECT
Authors: Korynevych A. , Chubinidze O.
Published: March 2020

The article reveals the peculiarities of application of universal jurisdiction in national law. In particular, attention was paid to the mechanisms for consolidating universal jurisdiction in the legislation of the Romano-Germanic and Anglo-Saxon legal systems, in particular as regards its subject-matter, personal and territorial application. An inalienable element of this study is the analysis of the powers and practice of the judicial authorities in this matter.
The main purpose of the article is a study of universal jurisdiction, based on classical cases of its consolidation in national law. Additionally, we provide the consideration of issues of practical
application thereof in cases of war crimes. The conclusion is that national legislation has moved to a more narrow understanding of universal jurisdiction. Most often, in order to start a case, the complainant must be present before the national court. It is important that the offenses have a connection with public interests of the state iudex loci deprehensionis. The problem is also that the consolidation and application of universal jurisdiction at the national level has not been yet unified.
QUANTITATIVE ANALYSIS OF TRADE COMPLEMENTARITY BETWEEN UKRAINE AND THE EU
Authors: Shnyrkov O. І. , Pliushch D. S.
Published: March 2020

The article outlines the perspective benefits of deepening integration processes between Ukraine and the European Union. Groups of Ukrainian goods have been identified, which exports to the EU are increasing dynamically. EU countries have been identified in which exports from Ukraine have been growing rapidly in recent years. The relations and nature of Ukraine's trade with the EU countries have been analyzed. The conclusions on the development of trade potential after signing the Association Agreement with the EU have been formulated. The assessment of the Complementarity Index of Trade for Ukraine and the EU by 97 commodity groups according to the Ukrainian Classification of Goods for Foreign Economic Activity and the Harmonized Commodity Description and Coding System for 2011-2018 has been carried out. The dynamics of change of complementarity indices are analyzed and the predicted indices of the countries for 2019 and 2020 are calculated. It has been proven that mutual trade in a free trade area is mutually beneficial for Ukraine and the EU, as Ukraine and the EU benefit from increased trade, and establishing international partnerships between their businesses and organizations can be particularly beneficial in the long term perspective. It is proposed to deepen international industry cooperation in order to develop competitive advantages and strengthen its position both on the Ukrainian market and the European market.
Challenges of Compulsory Seizure of Private Property by the State through Requisition, Confiscation and Nationalization under the Civil Legislation of Russia
Authors: Bogdanov E. V.
Published: March 2020

The existence of extraordinary circumstances, which should be understood as circumstances unavoidable under these conditions, constitutes the condition for requisition. The Civil Code of the Russian Federation gives state bodies a certain freedom in carrying out requisitions, as it is hardly possible to list all exceptional circumstances when additional equipment or other property will be required both to prevent the development of emergencies and to deal with their consequences.

Civil law confiscation involves the termination of private property and the emergence of state ownership of confiscated property. Therefore, it is impossible to treat as confiscation the seizure of tengible media according to Para. 4 of Art. 1252 of the Civil Code of the Russian Federation, because they were produced in violation of the law and, therefore, ownership has not arisen. The paper also substantiates the conclusion that nationalization requires relevant property to come not into the property of the State, but into the national property. In the author’s opinion, the currently existing State property does not contain any hints of national property, and it can be stated that the Russian people even more than previously are removed from the property of the State and are excluded from State responsibility. Nationwide property serves as a foundation of the civil society.
Protection of Personal Data in Digital Environment
Authors: Soldatova V. I.
Published: March 2020

In recent years, the application of legislation in the field of personal data has become the focus of attention of legal scholars. With the development of digital technologies, the problem of protection of personal data becomes especially urgent. The importance of personal data is so great that some scholars treat them as intangible goods. In order to protect the interests of citizens, our State takes measures to localize citizens’ personal data by statutory regulation of the Russian segment of the Internet. Such remedies as the right to be forgotten and personal data anonymization are also applied.

However, the practice, including judicial practice, shows that the available means of protection of personal data are insufficient in the context of new technologies. However, the practice of application of laws on personal data reveals a number of problems that need to be addressed. The attribution of specific information about natural persons to personal data leads to a number of questions with regard to the practice of the activities of state bodies. Under currently effective Article 3 of the Federal Law, the term personal data refers to any information relating directly or indirectly to a certain or definable natural person (subject of personal data). At the same time, the law does not specify which data about an individual refers to personal data. Due to this broad understanding of personal data, questions arise concerning the attribution of paticular information about an individual to personal data. In this regard, the definition of criteria for the attribution of specific information about a person to personal data becomes an important theoretical task.

The issues of primary concern include: 1) strengthening of responsibility for violation of personal data legislation; 2) giving priority to the issue of neutrality of the Internet, 3) solving the problem of the balance between direct access to publicly available data and the need to protect personal data. In the author’s opinion, it is necessary to ensure by means of comprehensive measures the priority of protection of personal data of citizens. This problem is of particular importance in connection with the elaboration of new laws on the digital profile of citizens.
Competition as an Object of Criminal Law Protection
Authors: Danilovskaya A. V.
Published: March 2020

Problems of understanding of criminal law protection of competition repersent a very topical subject for research. There is no uniform opinion in the criminal law doctrine on this point. However, the emergence of a common concept of competition protection could contribute, inter alia, to a more effective response to cartels, which pose a threat to the economic security of the country, other illegal forms of restricting competition. All available ideas of researchers concerning the need for independent criminal law protection of competition can be divided into two categories: 1) some authors differentiate a separate group of crimes agains competition; 2) others include them in a general or specific group of business crimes. The article substantiates the author’s opinion concerning the issues of recognition of competition as an independent object of criminal law protection and the problems arising due to it. The author has tried to find answers to existing in criminal law issues of protection of competition in other areas of knowledge and came to the conclusion that they can be justified by an economic approach to the analysis of concepts of “competition” and related to it both economic and legal processes and phenomena. By studying scientific economic views, the views that have been developed in the science of criminal law can be both confirmed and refuted. In addition, a cross-sectoral legal approach can help to address individual issues. Thus, the science of constitutional, criminal, civil and competition law, as well as law enforcement in these areas have developed and strengthened a number of ideas with regard to the regulation of economic (business) relations and their protection. One of them is based on the good faith of economic actors. An integral part of of activities of such actors is competition. The author concludes that the necessity of criminal law protection of competition is predetermined by the Constitution of the Russian Federation and other normative legal acts, and suggests that we understand fair competitive relations as an object of criminal law protection.
Legal Regulation of Cross-Border Shipping of Dangerous Goods in the Conditions of Digitalization
Authors: Skachkov N. G.
Published: March 2020

The author explores the legal aspects of network space risks, when legal imperatives are laid for the transportation and stay of a consignment of dangerous goods on board a ship. It is concluded that it is difficult to choose the law to be applied. In this regard, the material norms that make up the operational risk space can serve as a guide. Their selection is often a precursor to earning assets net operating profit. At the same time, the variety of legal facts with which the acquirer on arrival of property associates his right to file an ownership claim is formulated either in the contract of connection or accession. Therefore, separate prerequisites for the emergence of business and legal risks at the stage of abandoning consumer insurance in favor of its property qualification are highlighted. The paper shows types of encumbrances that accompany the problems of optimizing the costs of insurance against cyber risks. Even if insurance companies find their offer profitable for customers, the basis of the risk of financial loss is still the recovery of lost data. The insurer is forced to dispose of advanced analytical developments, such as, for example, blockchain or smart contracts that are very common today. Policyholders, in turn, use digital distribution and other virtual service models to not only reduce costs to a minimum, but also gain competitive advantages. The author analyzes the norms of the Convention acts on the transboundary shipping of dangerous goods. The International standards of TV and radio communications ISO/IEC 11801 and ISO/IEC 27001 (ISMS — 2018) are studied, and the conclusion is made that the threat to technological resources is identified with a comprehensive legal strategy for owner protection.
Optical Properties of a Glass Ceramic and an Indirect Resin Composite: Effects of Polishing and Staining
Authors: Dellazzana Fernando Zurlo , Rodrigues Camila Silva , Mallmann André , Jacques Letícia Borges
Published: March 2020

AbstractLittle information is available about the optical behavior of glass ceramics and indirect resin composites. This study aimed to evaluate if an indirect resin composite can present similar behavior of color stability and translucency to a glass ceramic after polishing and aging in staining beverage. Specimens of a dental ceramic (IPS e.max Ceram) and an indirect resin composite (SR Adoro) were made. Half the specimens of each material were polished with disc-shaped tips. Groups were divided according to aging media: distilled water or immersion in red wine for 20 min/day during 30 days. CIE L*a*b* coordinates were measured with a spectrophotometer at baseline and after 30 days of aging. Color change was calculated by CIEDE2000 and translucency was calculated by contrast ratio (CR). Statistical analysis were performed with ANOVA and Tukey tests. Aging in red wine caused perceptible color change in both materials. Polishing only increased color change of indirect composite when aged in red wine. Ceramic groups showed greater opacity than the composite in all measurements. The indirect composite remained more translucent and results showed that it is capable of presenting color stability similar to a ceramic. However, polishing seems to increase its color change. Keywords: Ceramics. Color. Composite Resins. Dental Polishing. ResumoPouca informação comparando o comportamento óptico de cerâmicas vítreas e resinas compostas indiretas estão disponíveis na literatura. O objetivo deste estudo foi avaliar se uma resina composta indireta pode apresentar comportamento semelhante a uma cerâmica vítrea em relação à estabilidade de cor e translucidez após polimento e envelhecimento em meio altamente pigmentante. Espécimes de uma cerâmica vítrea (IPS e.max Ceram) e uma resina composta indireta (SR Adoro) foram preparados. Metade dos espécimes de cada material foram polidas com pontas de polimento. Os grupos foram divididos conforme o meio de armazenamento: água destilada ou vinho tinto por 20 min/dia durante 30 dias. As coordenadas CIEL*a*b* foram medidas com espectrofotômetro previamente e após os 30 dias de armazenamento. A alteração de cor foi calculada pela equação CIEDE2000 e a translucidez foi calculada por razão de contraste. A análise estatística foi realizada pelos testes ANOVA e teste de Tukey. O armazenamento em vinho levou a uma alteração de cor perceptível nos dois materiais. O polimento apenas causou alteração de cor na resina composta indireta quando imersa em vinho tinto. A resina composta indireta manteve-se mais translúcida e os resultados mostraram que esse material é capaz de apresentar estabilidade de cor semelhante à cerâmica. No entanto, o polimento parece aumentar sua alteração de cor. Palavras-chave: Cerâmica. Cor. Polimento Dentário. Resinas Compostas.
Training for Cost-Effectiveness vs. Training as Tax Evasion Tool – A Study on Selected Private Companies in Bangladesh
Authors: Hossain Tanjela , Noor Md. Asad
Published: March 2020

Bangladeshi organizations consider employee training as an indispensable strategic tool for enhancing employee’s performance. Although training seems to be an expense, it is regarded as an investment. Every company is increasing the amount of the budget on training programs showing the reason that training brings the competitive edge. The study is focused on analyzing the tendency of increasing the training budget to know whether it is an investment or an evasion medium of tax in Bangladesh. A survey has been administered to find the degree of effectiveness of training programs, the utilization of budget on training, the cost-effectiveness of training programs and the possibility of training programs used as a tax evasion medium in Bangladesh. We have collected data through a semi-structured questionnaire from a sample of 200 employees working in 20 private organizations located in Dhaka city. We have observed from our survey that most of the time training programs held in different organizations in Bangladesh are not always effective. Trainees are not getting the most out of it. Contrary to the expectation, the analysis showed that the training budget is not sufficient. Although companies are increasing the amount of the training budget every year, it is not enough to give best results. And the budget is not utilized effectively in many cases. For this, many company’s performance in cost-effectiveness of training is not satisfactory. The formal evaluation method is not followed in every company, and the training programs are not improved always. Every organization doesn’t conduct cost and benefit analysis of training programs. The study has also found that training can be used as a tax evasion tool and in many organizations, it is somewhat being used. Training program opens up the opportunity to include false expenses which increases the total cost. The result of increased expense is a decrease in taxable profit. We have used mean, standard deviation, variance, percentage analysis, hypothesis testing, etc. for statistical analysis.
Quality of Work Life among Women Employees Working in RMG Sector of Bangladesh
Authors: Hossain Tanjela , Shirazi Hasan
Published: March 2020

“Quality of work life” has become the buzzword for the contemporary organization. Employees are more concern about their work environment ever, which is one of the most important factors to determine the quality of work life (QWL). It refers to the favorableness or unpleasantness of a job environment for people. The increased complexity of today’s work environment poses several challenges, especially for women employees who are working in different garment factories. It is now the high time for the Ready-made Garment (RMG) sector to be aware of improving the QWL. Our study focused on the factors influencing the quality of work life of women employees, their level of job satisfaction. We have tried to assess the QWL of women employees working in selected garment factories which are located in Gazipur district. We have collected data through a semi-structured questionnaire from a sample of 500 women employees. The findings of the study project various indications about concerned issues where the organization can concentrate to bring about better QWL life so that they get more satisfied women workforce. For statistical analysis mean, percentage, hypothesis testing, ranking order method and weighted average method were calculated. The ultimate findings of the study reveal that there is a significant relationship between work experience and participation in decision making for women employees. The survey study also shows that authority’s willingness is also an influential parameter to improve the QWL. Another interesting finding of our survey focuses that women employees have been given the least priority to salary as a measure to enhance QWL.
Corporate Social Responsibility (CSR) of MNCs in Bangladesh: A Study on Nestlé Bangladesh Limited
Authors: Ali Md. Monsur
Published: March 2020

The article CSR of MNCs in Bangladesh scrutinizes how multinational companies conduct corporate social responsibility (CSR) in Bangladesh. The purpose of the study is to observe the framework of CSR areas and contribution to those areas by the Nestlé Bangladesh Limited. It considers the structure of CSR in the business of Bangladesh, which is now globally a vital issue for the development of society. It explains the systems of adopting CSR by the MNCs in Bangladesh, we can begin to see what implications arise from the fact that CSR is a financially developed nations’ concept. Developing country like Bangladesh is considered lagging behind in its understanding and adoption of CSR practices. Generally corporations do not expose their policies. This article tried to explore current practices of CSR by the leading MNC like Nestlé Bangladesh Limited which is operating its business activities proudly for the long since.
Factors Affecting Islamic and Conventional Mutual Funds’ Returns. A Comparative Analysis of Different Classes of Funds in Pakistan
Authors: Ahmed Imran , Siddiqui Danish Ahmed
Published: March 2020

This study aims to analyze and investigate the factors influencing returns of Islamic and conventional mutual funds in Pakistan. Furthermore, this study aims to investigate whether macroeconomic and systematic factors affect Shariah compliant Equity, Income and Assets allocation Mutual Funds differently as compared their conventional counterparts. Different statistical techniques like correlation and regression analysis were applied to study their effect. The study concluded that macro-economic factors have an impact on both conventional and Islamic mutual funds however their impact seems to be insignificant at large. Overall funds behaved negatively with discount rate, inflation and GDP, whereas positively with trade and market index. Apart from income funds that were affected positively with discount rate. Furthermore, income funds were not affected by market index.  Moreover, inflation and GDP that is usually backed by higher interest rates, also effects overall returns negatively. There was no significant difference in the behavior among the Islamic and conventional funds with respect to the above-mentioned factors. Lastly, there was high correlation among both the equity and asset allocation based mutual funds (both Islamic and conventional). It was also found that asset allocation funds had close resemblance to equity-based funds as compared to income-based funds in term of factors influencing their returns, which suggested that most of the asset allocation funds have more portion of equity as compared to debt and could be considered high risk. Hence, they seem to be against Modern portfolio theory Markowitz (1952) presuming it to be in a minimum level of risk.
Adverse Effects of Climate Change in Bangladesh: its Physiological and Economic Impacts
Authors: Jahan Nusrat
Published: March 2020

Rapid changing of climate, the effects of greenhouse and global warming, is an alarming situation of the global map with its adverse effects, sending several countries under the waves. Unfortunately, Bangladesh stands at the peak of climate attacks. The land, water, and weather are being enormously affected by this outbreak of climatic changes. The dangers will intensify, if the precautionary measure is not taken immediately. However, to offset the grave concerns of unintended climatic changes in Bangladesh, there is no any significant initiative is taken. The changes will put its adverse impact on the socio- economic conditions of the country, putting the next generation on the line. Some ominous signs are already there for the concerned to respond with the required amount of fervor.

JEL Classification Code: F64
La spatialité de l’Histoire dans l’œuvre de Dominique Fortier
Authors: Bouchard Pierre-Olivier
Published: March 2020

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Non-haemorrhagic causes of obstetrical intensive care unit admissions in tertiary care setting
Authors: Kamal Preet , Kaur Surinder , Kaur Harleen , Nagpal Madhu
Published: March 2020

Background: Management of critically ill obstetric patients involve intensive monitoring in intensive care unit. In present scenario there are significant number of obstetric patients with sepsis, tropical diseases and medical illness that require ICU care. The aim of this study was to evaluate in more detail the non-haemorrhagic causes of obstetric ICU admissions and to identify and adopt high risk strategies as prime learning objective.Methods: It is a prospective ongoing study conducted in 50 patients in SGRDUHS, Amritsar from December 2016 to October 2019, who were admitted in obstetric ICU, out of them 30 cases were attributed to non-haemorrhagic obstetric causes. All demographic parameters along with gestational age, diagnosis on admission, intervention done prior to shift to ICU and details of treatment given in ICU were evaluated. Patient outcome, review of mortality and area of improvement were also noted.Results: Majority of the patient (70.1%) were admitted in 3rd trimester. Obstetric sepsis (13.33%), infective diseases (16.66%), tropical conditions (16.66%), medical disorders (26.66%) and hypertensive disorders (26.66%) were the major causes of admission to obstetric ICU. There were 33.3% mortalities observed in present study and 40% were due to respiratory failure. In ICU mechanical ventilation was done in 63.3% cases and blood products were given in 33.3% of patients.Conclusions: A multidisciplinary approach is ideal to handle non-haemorrhagic situations especially related to medical disorders and tropical diseases. Review of the ICU admissions and periodic audit can improve management of morbidities as well as reduce maternal mortalities.
Study of number of children preferred and knowledge, attitude, practice regarding birth spacing and contraception among primigravida in urban setting
Authors: Vailaya C. G. Raghavendra , Vailaya C. R. Shubha
Published: March 2020

Background: Overpopulation is a major problem in 21st century India. 2012 census shows birth rate of 20.97/1000 people and death rate of 7.48/1000 people. Fertility rate in 2019 was 2.28 children per women. Many states implemented 2 child norms. Purpose of study is to understand the number of children preferred.Methods: A Cross sectional study was done amongst 200 primigravida women who attended antenatal clinic at SMC, Shimoga. A predesigned and pretested standard Questionnaire was used to know the number of children preferred, KAP about birth spacing, contraceptive use and unsafe abortions using objective questions.Results: Most women preferred 2 child norms across most subclasses. Most Muslims (85.7%) preferred ≥3 children. Though 100% were aware of family planning, only 46% chose to space their next pregnancy. 56.5% were in support of 2-child norm. Family pressure plays crucial role in 83.5% cases and 65.5% still opted sterilization as the first choice for contraception.Conclusions: India with high population density is staring at demographic disaster due to limited life resources. Right attitude towards birth spacing, contraceptive use, avoidance unwanted pregnancies and unsafe abortions is needed. Better female literacy, societal awareness and good medical facility at last mile is crucial. Male partner’s involvement in every step is vital.
A case report of congenital lobar emphysema
Authors: K. Aditya , K. Parvathi , V. Prabhakar
Published: March 2020

Congenital lobar emphysema (CLE), also known as congenital alveolar overdistension, is a developmental anomaly of the lower respiratory tract that is characterized by hyperinflation of one or more of the pulmonary lobes. CLE is a rare congenital malformation with a prevalence of 1 in 20,000 to 1 in 30,000. We are reporting a 4-month-old boy presented with complaints of cough and cold for 3 days with history of similar complaints in the past at age of 1month and 2 months. Investigations revealed hyperlucency of left upper zone with tracheal shift and mild shift of the heart to the right. Elective Left Upper Lung Lobectomy was done and Appropriate supportive therapy given and child recovered well.
Riccardo Schwartz (2019) Font y de Anta: Andalucía. Brilliant Classics
Authors: Syroyid Syroyid Bohdan
Published: March 2020

No todos los días puede uno permitirse el lujo de presenciar el estreno absoluto de una obra musical centenaria. Más aún, cuando dicho estreno implica la recuperación de uno de los principales ciclos pianísticos de la literatura española de la primera mitad del siglo XX. Este es el caso del reciente trabajo discográfico del pianista italiano Riccardo Schwartz, alumno del célebre pianista y musicólogo Paul Badura-Skoda (1927 – 2019). Schwartz nos complace con la recuperación de la Suite Andalucía del compositor sevillano Manuel Font y de Anta.
Holguín, S. (2019). Flamenco Nation: The Construction of Spanish National Identity. Madison: University of Wisconsin Press, 384 pp. ISBN: 978-0299321802.
Authors: Sánchez Rodríguez Virginia
Published: March 2020

Reseña de libro.
Ossa Martínez, M. A. (Ed.) (2017). Repertorio, historia y vivencias en la retaguardia: la Banda Municipal de Música de Cuenca en la guerra civil española. Albacete: Uno Editorial, 306 pp. ISBN: 978-84-17055-61-5.
Authors: Nogales Barrios Silvia
Published: March 2020

Reseña de libro
Audycje rocznicowe Zygmunta Haupta w „Głosie Ameryki” (1951-1960). Zarys problematyki
Authors: Krupa Barbara
Published: March 2020

Tekst poświęcony jest pracy Zygmunta Haupta jako redaktora rozgłośni radiowej „Głos Ameryki”. Analizie poddane zostały oryginalne skrypty autorskich audycji, które zachowały się w archiwum pisarza zdeponowanym na Uniwersytecie Stanforda. Tekst dzieli się na dwie części. W pierwszej scharakteryzowana została całość radiowej twórczości Haupta, ze szczególnym uwzględnieniem jej wymiaru propagandowego. W drugiej części szczegółowej analizie poddane zostały dwie reprezentatywne audycje, w których pisarz wykorzystał całe spektrum różnego rodzaju środków perswazyjnych, jednocześnie dbając o ich artystyczny wymiar.
Motywika tożsamości w tekstach Krzysztofa Vargi o tematyce węgierskiej
Authors: Vas Viktória
Published: March 2020

Artykuł poświęcony jest problematyce tożsamości w utworach Krzysztofa Vargi o tematyce węgierskiej. Narracja w prozie autora Gulaszu z turula łączy w sobie daleko posunięty krytycyzm i ironię z nostalgicznym obrazem życia codziennego i kultury. Szczegółowe analizy sztuki prozatorskiej Vargi ukazują pisarza jako świadomego i jednocześnie uważnego obserwatora węgierskiej rzeczywistości, który obnaża kolejne elementy składowe narodowych mitów i symboli, a jednocześnie ujawnia głębokie źródła własnej tożsamości.
Czarnogóra Andrzeja Stasiuka
Authors: Nowaczewski Artur
Published: March 2020

Autor analizuje obrazy Czarnogóry w prozie Andrzeja Stasiuka, inspirując się refleksjami zawartymi w Poruszonej mapie Przemysława Czaplińskiego. Ograniczenie przedmiotu analizy do tego państwa pozwala uwypuklić istotne cechy pisarstwa Stasiuka, nie zawsze dostrzegane przez krytykę. Przywiązanie do własnej pamięci i autorskiej wizji są w tej prozie ważniejsze niż cele, które przyświecają literaturze non fiction. Jest ono przez to zależne od stereotypów na temat Bałkanów oraz własnych powierzchownych obserwacji.
Nuevas tecnologías, guías de manejo y su aplicación en la obstetricia moderna: el ejemplo de la restricción del crecimiento intrauterino (RCIU)
Authors: Sanín-Blair José Enrique , Gutiérrez-Marín Jorge Hernán
Published: March 2020

La medicina perinatal ha evolucionado en los últimos 25 años de una manera significativa; sin embargo, en temas como el parto prematuro se han obtenido resultados pobres en comparación con los esfuerzos económicos, tecnológicos y humanos. En el campo del crecimiento fetal anormal, la generalización en el uso de los medios tecnológicos derivados del ultrasonido ha revolucionado irreversiblemente el curso clínico de una enfermedad que hasta hace 2 décadas era de valoración subjetiva e indirecta por medio de mediciones de la altura uterina o ganancia ponderal y confirmación posnatal o post mórtem, con mínimos conocimientos relativos a la historia natural.1 De hecho, no hay consistencia entre los resultados de trabajos presentados en los años ochenta con los obtenidos actualmente con referencia a fetos con crecimiento anormal. Da la impresión de que se hablara de dos entidades diferentes.
Exactitud del test ADN-HPV para la detección de la enfermedad cervical de alto grado (NIC 2+) en mujeres con anormalidades citológicas (ASC-US y LSIL), afiliadas a la seguridad social en Bogotá (Colombia)
Authors: Isaza-Ruget Mario Arturo , Perez Gonzalo , Morales-Reyes Olga Lucía , Deantonio-Suárez Rodrigo , Alvarado-Heine Catherine , Trujillo Lina María
Published: March 2020

Objetivo: evaluar la exactitud de la prueba ADNHPV en el diagnóstico de lesiones premalignas cervicales de alto grado (HSIL, por sus siglas en inglés) en mujeres con alteraciones citológicas ASC-US (células escamosas atípicas de significado indeterminado) y LSIL (lesión escamosa intraepitelial de bajo grado).Metodología: estudio de validez diagnóstica y de cohorte transversal, realizado en mujeres con diagnóstico citológico de ASC-US o LSIL entre octubre de 2006 y enero de 2008, pertenecientes al Programa de Tamizaje de Cáncer de Cérvix de una aseguradora privada en Bogotá (Colombia). Se comparó el resultado de la colposcopia y de la prueba de ADN-HPV con la patología del cérvix como patrón de oro.Resultados: de las 429 mujeres, 344 (80,2%) presentaron ASC-US y 85 (19,8%) LSIL. Las prevalencias de infección por HPV de alto riesgo fueron 52,9% y 75,7% en pacientes con reporte citológico de ASC-US y LSIL, respectivamente. A las 379 de las 425 pacientes se les practicó biopsia, 24 (6,3%) dieron positivas para HSIL. La sensibilidad de la prueba ADN-HPV para detectar lesiones de alto grado (NIC 2+) en las mujeres con reportes de citología ASC-US y LSIL fue 88% y la especificidad fue 44%. En 21 (87.5%) de los 24 casos de HSIL se detectó la presencia de HPV de alto riesgo.Conclusión: debido a que la prueba ADN-HPV tiene una sensibilidad superior a la citología cervicovaginal (CCV), ésta puede considerarse una alternativa útil para estratificar el riesgo y mejorar la aproximación diagnóstica de lesiones premalignas del cuello uterino en mujeres con reporte de ASC-US.
Aloinmunización RH: manejo anteparto. Revisión de la literatura
Authors: Molina-Giraldo Saulo , Moise-Jr Kenneth J.
Published: March 2020

Introducción: la aloinmunización Rh es una enfermedad frecuente en Colombia pese al uso de inmunoglobulina anti-D(Rho) en los embarazos de alto riesgo. Asimismo, es una condición que requiere la identificación temprana de los factores de riesgo, así como el adecuado tamizaje con el fin de lograr una remisión oportuna a una unidad materno-fetal con experiencia para disminuir las complicaciones fetales y brindar la terapia indicada en caso de ser necesario.Objetivo: revisar la exactitud de los métodos de tamizaje y de diagnóstico temprano, así como también la efectividad de los métodos no invasivos e invasivos de tratamiento.Metodología: se realizó una revisión de la literatura existente de acuerdo con las bases de datos PubMed, EBSCO, Ovid y ProQuest desde el año 2000 hasta el 2008, la cual incluyó artículos de revisión e investigaciones originales.Resultados: la titulación de anticuerpos y el pico de velocidad máximo sistólico de la arteria cerebral media son las herramientas que permiten realizar la evaluación y la identificación de las pacientes en riesgo. El tratamiento incluye transfusión intrauterina y parto oportuno mientras que la prevención con la inmunoglobulina anti-D (Rho) continúa indicada.Conclusión: la aloinmunización Rh aún es una patología de interés en el control de las pacientes obstétricas de bajo y alto riesgo. El conocimiento que se obtenga de la enfermedad permitirá realizar el diagnóstico oportuno y, de esta manera, identificar los fetos en riesgo que son susceptibles de terapia intrauterina.
Fitoestrógenos: revisión de tema
Authors: Díaz-Yamal Ivonne , Munévar-Vega Liliana
Published: March 2020

Introducción: los fitoestrógenos son sustancias encontradas en gran variedad de plantas. Recientemente, han sido propuestos para el manejo de las alteraciones asociadas con la menopausia.Objetivo: entender la bioquímica y farmacodinamia de estos compuestos y la evidencia que existe sobre su uso en la práctica clínica.Metodología: se realizó revisión de artículos en las siguientes bases de datos: PubMed, Ovid, MDconsult, ProQuest y Science Direct.Resultados: se encontraron dos metaanálisis, 5 estudios clínicos aleatorizados y controlados y 6 artículos con series de casos o descriptivos. Tanto los estudios clínicos como las series de casos presentaron un número reducido de pacientes. Dos metaanálisis en los que se comparó el uso de fitoestrógenos para los sofocos u oleadas de calor, indicaron que su efectividad es similar a la del placebo mientras que no se encontró evidencia de efectividad en otros síntomas perimenopáusicos. En los estudios se evaluó la seguridad de los fitoestrógenos a nivel endometrial y de seno; aún así, no se observó mayor riesgo con su uso.Conclusión: no hay evidencia que sustente el uso de los fitoestrógenos; por lo tanto, se deben realizar más estudios que demuestren la efectividad o no de estos compuestos en los síntomas perimenopáusicos.
Síndrome de Ogilvie poshisterectomía: reporte de un caso y revisión de la literatura
Authors: Hernández-Pinzón Jairo , Castillo-Zamora Marcos , Rodríguez Carolina
Published: March 2020

Objetivo: presentar el estudio y el tratamiento que se le realizó a una mujer embarazada que presentó Síndrome de Ogilvie (SO) como complicación de una histerectomía obstétrica, así como describir la epidemiología,lafisiopatología,loshallazgosclínicos después de los procedimientos gineco-obstétricos y el tratamiento de esta patología mediante una revisión de la literatura.Presentación del caso: mujer de 28 años de edad con embarazo de 38 semanas de gestación quien después de parto vaginal eutócico sufrió atonía uterina. Debido a la falta de mejoría con el manejo médico, se le realizó una histerectomía abdominal subtotal, presentando picos febriles, intolerancia a la vía oral, taquicardia, distensión e hipertimpanismo abdominal con dolor a la palpación superficial y profunda en hemiabdomen derecho y peristaltismo disminuido durante el posoperatorio. La radiografía de abdomen evidenció un cuadro obstructivo con origen probable a nivel del intestino delgado, por lo que se le practicó una laparotomía exploratoria donde se le encontró peritonitis fecal y perforación colónica a nivel de la válvula ileocecal, sin evidencia de obstrucción mecánica.Discusión: el SO se caracteriza por la dilatación masiva y progresiva del colon en ausencia de una obstrucción mecánica. Se desarrolla principalmente en pacientes hospitalizadas con graves condiciones médico-quirúrgicas, pero también se presenta frecuentemente después de procedimientos gineco-obstétricos. Debido a que este síndrome se ha visto asociado con una alta morbimortalidad, es necesario que el gineco-obstetra lo tenga en cuenta como diagnóstico diferencial y esté atento a su presentación como complicación de cirugías obstétricas o ginecológicas.
Cardiomiopatía periparto: reporte de un caso y revisión de la literatura*
Authors: Hernández-Guzmán Alejandro , Nieto-Calvache Albaro José , Medina-Palmezano Virna , Delgado-Gutiérrez Julián
Published: March 2020

Objetivo: realizar una revisión de la literatura acerca de los aspectos más relevantes del manejo de la cardiomiopatía periparto (CMPP) en la unidad de alta dependencia obstétrica.Presentación del caso: presentamos un caso clínico con diagnóstico de CMPP al cuarto día posparto. El ecocardiograma identificó un compromiso de la fracción de eyección. El tratamiento intensivo y adecuado permitió la supervivencia y la recuperación de la función ventricular sistólica izquierda.Discusión: la CMPP es una enfermedad cardíaca rara que ocurre durante el período posparto, la cual ha sido reconocida como una entidad distinta al infarto de miocardio cuyos signos y síntomas tempranos de falla cardíaca pueden estar ocultos por las modificaciones normales del embarazo. La evidencia indica que la tasa de letalidad varía entre 9% y 56% con la mayoría de las muertes ocurridas dentro de los tres primeros meses posparto. Su diagnóstico se basa en la presentación clínica de falla cardíaca congestiva y la evidencia objetiva de disfunción sistólica ventricular izquierda. Por lo tanto, el tratamiento debe incluir la terapia para falla cardíaca, la cual implica la reducción de la precarga, la poscarga y el uso de agentes inotrópicos, diuréticos, vasodilatadores y la digoxina. Igualmente, los inhibidores de la enzima convertidora de angiotensina (IECA) deben ser incluidos en el tratamiento posparto de la CMPP. La finalización del embarazo depende del estado funcional y de la respuesta al tratamiento inicial. Por esto, el obstetra juega un papel fundamental en el abordaje multidisciplinario de las mujeres con esta entidad y debe coordinar los esfuerzos del equipo tratante.
Modifiye lapidus prosedürünün uzun dönem sonuçları
Authors: AKKURT Mehmet Orçun
Published: March 2020

Amaç: Çalışmamızda 2004-2012 yılları arasında Modifye Lapidus prosedürü uyguladığımız 67 hastayı restrospektif olarak değerlendirdik.Gereç ve Yöntemler: Hastaların 61’I Kadın,6’sı erkekti. Hastaların ortalama yaşı 51’di .Hastaların ortalama takip süresi yaklaşık 10yıl’dı (6-14 yıl). Hastaların klinik muayenesiyle birlikte ameliyat öncesi ,ameliyat sonrası en son takipte basarak çekilmiş ayak grafileri alınmıştır.Bu grafilerde intermetatarsal açı (İMA),halluks abduktus açısı (HAV) ve tibial sesamoid pozisyonu (TSP) değerlendirildi. Bulgular: Hastalarımızda İMA ve HAA’da sırasıyla 9.6⁰ ve 21.4⁰ ortalama düzelme sağlandı. İMA ve HAA’da ameliyat öncesi ve ameliyat sonrası radyografilerde istatiksel olarak anlamlı bir fark mevcuttu (p<0.001).Kaynamama nedeniyle revize ettiğimiz bir hastamız hariç hiçbirisinde greft kullanmadık.Komplikasyon olarak 4 hastamızda kaynamama,2 hastamızda kaynamama,3 hastamızda intraoperative kılavuz teli kırılması,2 hastamızda vida kırılması,5 hastamızda yüzeysel enfeksiyon,1 hastamızda FHL rüptürüyle karşılaştık.Takiplerde hiçbir hastamızda halluks valgus rekürrensiyle karşılaşmadık. Sonuç: Biz Modifiye Lapidus artrodezi 1. sıra hipermobilitesiyle birlikte olan halluks valguslarda ve ciddi halluks valguslarda kullanabileceğimiz ve kuvvetli düzeltme sağlayabileceğimiz bir prosedür olduğu kanaatine vardık.
Aritmi ablasyon öyküsü olan gebenin spinal anestezi eşliğinde sezaryenle doğumunda anemi yönetimi
Authors: TURK OZTERLEMEZ Naciye , IŞIK Gizem , INAN Gozde , GÜNAYDIN Berrin
Published: March 2020

Preoperatif dönemde görülen aneminin perioperatif dönemde hastanede kalış süresinin uzaması, yoğun bakım ihtiyacı gibi birçok morbidite ve/veya mortaliteye yol açabilen perioperatif kan transfüzyonu için güçlü bir prediktör olduğu bilinmektedir. Buradaradyofrekans aritmi ablasyon öyküsü olan anemik gebenin spinal anestezi altında elektif sezaryen sırasındaki doğum yönetimini sunmayı hedefledik. Güncel kanıtlara göre, cerrahi öncesinde anemi yönetimine göre, başarısız oral demir tedavisi nedeniyle halen anemik olan gebe olguda spinal anestezi altında sezaryenle doğum sırasında peroperatif tek doz İV demir tedavisi uygulayarak aritmi ablasyon öyküsü olan gebeye yaklaşımımızı sunduk.
CASTRATION-RESISTANT PROSTATE CANCER: NEW PERSPECTIVES IN PHARMACOLOGICAL TREATMENT
Authors: Andreev Dmitry A. , Zavyalov A. A , Govorov A. V , Kokushkin K. A. , Davidovskaya M. Y
Published: March 2020

Prostate cancer remains one of the most actual problems in oncourology due to its high prevalence and resistance to therapy. Within 5 years of active treatment and follow-up, the castration-resistant prostate cancer (CRPC) develops in 10-20% of patients. This type of disease course resists treatments and leads to death. Medical resources distinguish two different forms of CRPC: non-metastatic and metastatic. Such separation is critically important because each of two forms requires different treatment algorithms. This paper summarizes the main outlines of foreign clinical guidelines and reviews the new treatment options for non-metastatic and metastatic CRPC as wells as the design and results of key clinical trials on drug efficiency. To prepare the review, the comprehensive literature search was conducted using PubMed/Medline, the Cochrane Library, EMBASE, CyberLeninka, e-library databases. The search line included phrases containing the following words: prostate cancer, castration-resistant prostate cancer, drug therapy, treatment algorithms, clinical studies, etc. In accordance to foreign guidelines, it is essential to determine the high risk patients with non-metastatic CRPC and promptly apply new therapeutic options including apalutamide and enzalutamide, which have proven being effective in clinical trials as therapies that attenuate the transition of the non-metastatic CRPC to the metastatic stage. Foreign medical guidelines propose to apply a wider set of treatment algorithms for patients with metastatic CRPC, for instance: considerations on possibilities to use the cabazitaxel instead of docetaxel in the 1st line therapy in patients with pre-existing mild peripheral neuropathy, etc. as well as new therapies - pembrolizumab and sipuleucel-T. The issues regarding the selection of patients with CRPC for specific treatment algorithms and defining the optimal sequence of therapeutic regimens as well as combining various regimens with minimizing toxic effects and maximizing patient benefits remain unsolved.
STUDY OF FEATURES OF FAMILIES WITH PRE-SCHOOL CHILD
Authors: Kravchenko I. A , Polunina N. V , Polunin Valery S.
Published: March 2020

The family of the child in the first three years of the formation of physical, mental health of the child. Goal- a study of the medico-social aspects of formation of health of preschool children and medical activity family. Materials and methods. Carried out selective posemejnoe study examined medical records 400 children of pre-school age and the results of the questioning of their parents, living in Moscow. Results. Noted that parental education factor has no impact on the incidence of children of preschool age, the incidence of children from families where parents smoke, are overcrowded apartments, violate sleep and overload children with additional developing classes reaches 5018.7 per thousand children in families with low medical activity more often there are children with bad health, parents often underestimate the health of their children and in a timely manner go to the doctor in case of illness of a child. In this regard, health workers must, in its activities, pay more attention to the observance of sanitary-educational work among the parents of pre-school children.
STUDYING OF LONG-TERM RESULTS OF PREVENTION HELP TO PATIENTS OF WORKING AGE WITH PARTICIPATION OF ТНЕ NURSING STAFF
Authors: Korolkova G. S , Tikhomirova Galiya I. , Zakharchenko Yu. I
Published: March 2020

The RF currently work a nurse can be considered as a new type of professional activity of medical, psychological, pedagogical and socio-legal nature, the purpose of which is to the preservation, enhancement and restoration of the health of patients. Purpose - the study received remote results of preventive nursing activities among working-age patients with arterial hypertension. Material and methods. Studied the results of observation and questioning students hypertensive patients aged 35-65 years in school prevention patients with arterial hypertension. The results. Researched group of patients with arterial hypertension (AH), among which were training classes on prophylaxis of recurrence and complications of AH on healthy lifestyle programme using the nursing process and without it and shows the efficiency of these activities. Conclusion. The use of educational technology training “Nursing process” showed their effective influence on enhancing treatment and prevention of the occurrence of relapses and complications in patients with AH.
THE RESULTS OF HIP REPLACEMENT IN PATIENTS WITH DIABETES TYPE 2
Authors: Ivanov Leonid V. , Guriev V. V , Yarygin N. V
Published: March 2020

It performed the analysis of the literature data on the peculiarities of the influence of type 2 diabetes mellitus on the endoprosthesis replacement of the steep joints in patients with diabetes mellitus outcomes. Reviewed the risk factors for complications of endoprosthetics, it is shown that in patients with diabetes mellitus operations on the hip joints are associated with higher rates of postoperative infection, the need for blood transfusion, the development of pneumonia and urinary tract infections, and increased hospital stays and higher rates nosocomial mortality. It was noted that in the course of making a decision on the performance of arthroplasty, surgical risk should be assessed for patients with diabetes, taking into account the possible complications of diabetes and the presence of other associated diseases. The basic principles of preoperative preparation, peri-and postoperative management of this cohort of patients are characterized.