bluuebunny/crossref_metadata_2025 huggingface dataset:
Polymorphism of Rs1800629 Gene of TNF-Α in the Pathogenesis of Acne Vulgaris
Authors: Malikova Nilufar N. , Karimov Khamid Y. , Arifov Saidkasim S. , Boboev Kodirzhon T.
Published: March 2024

Background: The study of the association between acne vulgaris and the TNF-gene polymorphism rs1800629 in the Uzbek population is discussed in this article. Methodology: The research was conducted on 165 patients with various clinical forms of acne vulgaris and 161 healthy donors.
Findings: During this research, allele frequencies and genotypes of rs1800629 polymorphism of TNF-α gene were found with statistically significant differences between the control group and subgroups of patients with acne vulgaris. As a result of the investigation, it was discovered that heterozygous genotype G/A should be a genetic marker for an increased risk of acne development, whereas homozygous genotype G/G should be a marker for a reduced risk of acne formation.
Patriarchal politics, online violence and silenced voices: The decline of women in politics in Zimbabwe
Authors: Mtero Shingirai , Parichi Mandiedza , Højlund Madsen Diana
Published: March 2024

In this year's elections in Zimbabwe, the number of women nominated and elected to national office decreased. This decline can be attributed to increased online harassment of women in politics, as well as financial obstacles and patriarchal attitudes. To reverse this trend, it is crucial for the government, political parties and civil society to address gender-based electoral violence effectively. Additionally, the government should genuinely implement gender quotas, focusing on empowering women in politics rather than using quota as a means to improve their international image, attract international donor funds and secure more women voters.
Giaccaglia, Clarisa, Calderón Emilse, Dussort, María Noel, Marchetti, Agustina (2022). Soplan nuevos vientos: ¿Tiempos nuevos para BRICS? Marcos conceptuales y pujas de poder en la negociación de la agenda internacional. Rosario: UNR Editora. ISBN 978-987
Authors: Astudillo Naveda Valentina
Published: March 2024

En el centro del debate sobre el orden internacional liberal y la transición hegemónica mundial, caracterizado por el declive relativo de Estados Unidos y el ascenso de China, resurge el interrogante sobre quién o quiénes diseñan la agenda internacional del actual tablero mundial. A inicios del siglo XXI, como consecuencia de pujas de poder, comenzaron a aparecer potencias emergentes en la escena principal de la discusión de la agenda internacional, exigiendo cambios tanto en las normas como en los temas bajo discusión. Estos emergentes fueron identificados bajo la iniciativa gubernamental BRICS surgida en 2009 conformada por Brasil, Rusia, India, China y desde 2011, Sudáfrica.
Management of plastic waste as industrial raw material in the perspective of protecting the environment the environment
Authors: Biyanto Biyanto , Fadlan Fadlan , Prasetiasari Christiani
Published: March 2024

Purpose: The purpose of this study was to determine the legal regulation of plastic waste management as an industrial raw material from the perspective of protecting the environment, and how the implementation, constraining factors, and efforts to manage plastic waste as industrial raw material from the perspective of protecting the environment.

Research methodology: The research method of this journal is normative juridical (legal research) through a literature study with an empirical juridical approach (sociological juridical) through field studies aimed at empirically obtaining legal knowledge.

Results: The results showed that the legal regulation of plastic waste management as an industrial raw material from the perspective of protecting the environment; Article 36 of Law Number 32 of 2009 regulates activities that are required to have an EIA or UKL-UPL must have an environmental permit, and environmental permits are issued by the Minister, governor, or regent/mayor. Specifically, plastic waste management is also regulated in Article 4 of the Government Regulation of the Republic of Indonesia (Number 22 of 2021). The implementation of plastic waste management as an industrial raw material from the perspective of protecting the environment at PT Agromas Batam Pratama resulted in the evaluation of wastewater quality exceeding the predetermined quality standards. There are various obstacles, such as policy, availability of plastic waste, technology, and human resource awareness. These constraints affect the management of plastic waste in the context of environmental protection. However, the government's supervisory efforts, namely periodic evaluation, have the potential to cause environmental pollution.
Using copper-coated round rod electrodes at various depths in freshwater marshes
Authors: Putra Dian Eka , Nawawi Zainuddin , Jambak M. Irfan
Published: March 2024

Purpose: High-voltage electrical equipment requires a grounding installation in order to protect lives in freshwater swamps with a hydrogen potential of 6.75. To build a grounding structure, it is required to know the resistance value and grounding materials, namely copper-coated rod electrodes at different depths.

Research methodology: The research was conducted in a freshwater swamp close to the shampooing substation using field observations and direct measurement of soil resistance values, followed by a literature review and comparisons using COMSOL simulation and FEM Analysis.

Results: The results of direct research and simulations indicate that in order to accomplish a grounding resistance value < 5 ohms according to the PUIL 2011 standard for a single rod system made of copper, it is necessary to optimize the depth of the grounding electrode within a range of 10 meters, which differs from the simulation results of ground resistance measurement and the Comsol application. The percentage error is 1.05%.

Limitations: This research analyzes the results of measurements and grounding analysis using Comsol Multiphysics at a depth of 1 meter for a particular type of copper-coated round rod electrode at depths of 1, 1.5, and 2 meters.

Contributions: The results of the study offer information on the usefulness of grounding resistance in freshwater wetlands with a pH greater than 6, where several rod electrode types are utilized to compare future research.
Developing An Islamic Adab-Based Teacher Leadership Model to Improve Teacher Performance in Islamic Boarding Schools
Authors: Ramdani Dani Mohammad , Syam Husain , Saman Abdul
Published: March 2024

Purpose: This study aims to overcome the problem of improving teacher performance by improving the quality of teacher leadership.

Research methodology: This development research adapts the Borg and Gall research and development model, with the research subjects being teachers. This study has five main objectives: describing the needs of teachers to develop an Islamic manners-based teacher leadership model to improve teacher performance, designing and developing a prototype of the model, evaluating the validity and practicality, and assessing the effectiveness of the teacher leadership model. Data were collected from experts and practitioners using observation methods, implementation surveys, and assessment sheets. Data analysis techniques involved quantitative and descriptive analyses.

Results: The results of the development research indicate that (1) teachers’ need for Islamic adab-based teacher leadership is very high as a guide for learning and mentoring students on a daily basis; (2) the prototype of this teacher leadership model includes a series of steps, starting from the flowchart, framework, and components, to the stages of treatment for teachers; and (3) the assessment of the feasibility of the Islamic adab-based teacher leadership model shows a very high validity category with an average score of 3. 66, (4) Its practicality is assessed as practical with an average value of 3.20; (5) there is a real difference in the effect of applying the Islamic adab-based teacher leadership model at Insan Cendekia Madani High School before and after the application of the model to improve teacher performance with a survey of the impact of model implementation that reaches very high normality values of 0.529 and 0.128 > 0.05, t-test 0.000 < 0.05, and moderate N-Gain 0.60 < 0.70, with a percentage of moderately effective results at 58%.
Digital Module Development of Islamic Education to Improve Student Independence in Learning at Middle School Program
Authors: Bukhori Ahmad , Gani Hamsu Abdul , Yahya Muhammad
Published: March 2024

Purpose: This study aims to determine: (1) the need for the development of digital modules of Islamic Religious Education to improve student learning independence; (2) the design of the development of digital modules of Islamic Religious Education to improve student learning independence; (3) the validity of digital modules of Islamic Religious Education to improve student learning independence; (4) the practicality of digital modules of Islamic Religious Education to improve student learning independence; and (5) the effectiveness of digital modules of Islamic Religious Education to improve student learning independence.

Research methodology: This study examines a type of research and development (R&D) that produces a product in the form of a digital module for Islamic Education. This development utilizes the ADDIE model, which consists of five stages: analysis, design, development, implementation, and evaluation. The instruments used in this study included a questionnaire on student independence in learning. The questionnaire was administered to 70 students at the Insan Cendekia Madani Middle School Program, Serpong, South Tangerang City, to assess the achievement of student independence in learning in Islamic Education assisted by an online application or platform. This application is transformed into a product referred to as a digital module.

Results: The results show that the development of a digital module for Islamic Religious Education is needed to improve students' learning independence. Design or design produces a digital module of Islamic Religious Education, along with supporting devices and research instruments. The product developed is a digital module of Islamic Religious Education to improve students' learning independence and instructions for using the digital module of Islamic Religious Education, lesson plans, and assessment sheets. The validation test results showed that the digital module was valid based on the experts' assessments.
Factors associated with the achievement of early detection of breast cancer with the SADANIS method
Authors: Kurrohman Taufik , Nurlita Sindi
Published: March 2024

Purpose: Breast cancer is one of the non-communicable diseases that contributes to the largest death rate for women in Indonesia. The purpose of this study is to find out the relationship between information exposure, family support and health care support with access to early detection of virgin breast cancer
Research methodology: The research design used was cross-sectional or cross-sectional. The research population was all women of childbearing age who were selected as samples. This research was conducted in the working area of ??the Air Itam Community Health Center, Pangkalpinang City, Bangka Belitung Province. Data collection was carried out in June-August 2023.
Results: The results show that the development of a digital module for Islamic Religious Education is needed to improve students' learning independence. Design or design produces a digital module of Islamic Religious Education, along with supporting devices and research instruments. The product developed is a digital module of Islamic Religious Education to improve students' learning independence and instructions for using the digital module of Islamic Religious Education, lesson plans, and assessment sheets. The validation test results showed that the digital module was valid based on the experts' assessments.
Point of Sale System Using Convolutional Neural Network for Image Recognition in Grocery Store
Authors: Roslan Naim Najmi , Saad Ahmad Fadli
Published: March 2024

The history of point of sale already has been told from a long time ago. The business nowadays is opting for the point-of-sale transactions because it was easy to sell the item to people face to face. This will build some trust between the cashier and the customer. The popular store that always customer need was the grocery store. However, the grocery store nowadays still not has a good feature for the point-of-sale system. The cashier still needs to scan the item through barcode scanner. This idea was led to make the point-of-sale transactions easier in the grocery store by applying the machine learning to the system. The problem for this project is the customer wait for a long time for their point-of-sale transactions to finish when bought the grocery items. The aim of this project is to detect the grocery items with convolutional neural network model for image recognition through camera within the main user interface. The Agile Development Life Cycle (ADLC) method is used in the development of Point-of-Sale System using Machine Learning for Image Recognition in Grocery Store. Moreover, this project is to evaluate the usability of the system using Post-Study System Usability Questionnaire (PSSUQ) approach. The PSSUQ evaluation is evaluated by the users of the system. The results of PSSUQ stated that the users satisfied with the system. The future research for this project is to make the point-of-sale system with a better model in the future. In conclusion, the system is works well and machine learning image recognition model also can detect the grocery item clearly.
A Review of Cross-Platform Document File Reader Using Speech Synthesis
Authors: Chukwudi Ogenyi Fabian , Eze Val Hyginus Udoka , Chinyere Ugwu
Published: March 2024

Document files are files used to store documents on storage devices primarily for computer use. Software is used to view these files, displaying their text content in a legible way. However, it is essential to have programs for transforming electronic files into versions usable by those who suffer from specific disabilities. This paper reviewed fifteen published articles in the field of document file reading.  It was observed from the review that various attempts have been made by different researchers in order to develop a software cable for converting document files that consist of text to an audio format. Text may now be easily translated into natural-sounding voice across many platforms using different software. It was observed from the systematic review that the use of AI such as the GPT-3.5 and GPT-4 Turbo Large Language Model (LLM) technologies has the best performance because it does not end at producing a vocal sound that is similar to human own, but it also translates different languages. In conclusion, cross-platform document file reader (text-to-speech) synthesis has improved user experiences in a variety of applications such as language learning, audiobooks and virtual assistants.
A Critical Assessment of Data Loggers for Farm Monitoring: Addressing Limitations and Advancing Towards Enhanced Weather Monitoring Systems
Authors: Eze Val Hyginus Udoka , Okafor Wisdom O. , Odo Jonathan Ikechukwu , Ugwu Chinyere N , Ogenyi Ogenyi Fabian Chukwudi , Edozie Enerst
Published: March 2024

This comprehensive review examines thirty-nine data loggers and their associated literature, systematically critiquing their design and implementation. The integration of data loggers in farm monitoring proves cost-effective, enabling the simultaneous monitoring of multiple parameters without human intervention. The accrued data, when logged over time, contributes to more accurate weather predictions, empowering farmers to strategically plan for upcoming seasons. However, the review reveals a prevalent issue among existing data loggers: many cannot read and record various weather parameters concurrently, coupled with insufficient storage capacity. This limitation hinders their suitability for prolonged, unattended data storage. Additionally, a significant number of the reviewed data loggers lack long-range wireless data transmission capabilities, restricting effective weather monitoring from a distance. The findings underscore the need for researchers to focus on developing advanced long-range data logger systems with enhanced memory storage capacities to address these identified shortcomings.
Teacher Professional Identity, Work Engagement, and Emotion Influence: How Do They Affect Teachers’ Career Satisfaction
Authors: Gong Yue , Wang Lei
Published: March 2024

Teachers’ behaviours significantly influence students’ learning outcomes but also play an important role in national development and construction. However, few studies have attempted to investigate the interrelationships between teachers’ professional identity, work engagement, emotion, and attitude towards career satisfaction. This study aims to explore the effect of professional identity and emotion on work engagement and career satisfaction separately and to investigate the influence of work engagement on attitude and, subsequently career satisfaction. A convenience sampling technique includes 221 valid questionnaires that were subjected to descriptive analysis followed by subsequent empirical testing of the populated hypotheses using SPSS and AMOS. Results showed that professional identity and emotion positively influence work engagement and career satisfaction respectively. Work engagement positively influenced attitude and, subsequently career satisfaction. Last, the theoretical and practical implications and limitations were discussed.
Organization of Knowledge in Light of Egan and Shera’s Social Epistemology and Elias’ Symbol Theory
Authors: Zandonade Tarcisio , Martínez-Ávila Daniel
Published: March 2024

Knowledge organization or information organization, in a narrower sense, is an area of Library and Information Science (LIS) concerned with activities such as document description, indexing, and classification performed in bibliographic and cybergraphic repositories for their rapid and economic retrieval for use by society. Knowledge organization is an essential second level knowledge product; while a first level knowledge production studies the scientific phenomenon via general social epistemology, especially in the guise commanded by Steve William Fuller’s program. In this second level, knowledge organization studies the problem of mechanisms and existing bibliographic systems and the extent to which they are congruent with the realities of the communication process and the findings of epistemological research via special social epistemology, an academic discipline created by Jesse Shera and Margaret Egan. Additionally, the definition of “symbol” as the essential object of information science is examined, following the theoretical foundation of information developed by Norbert Elias’ “The Symbol Theory”.
Heredograma Informacional
Authors: Souza Osvaldo de
Published: March 2024

Neste texto discutimos questões relacionadas à organização e representação do conhecimento no sentido de propor uma contribuição teórico-metodológica com possíveis impactos positivos na qualidade da informação. Caracterizando-se como uma pesquisa de natureza qualitativa do tipo exploratória com levantamento bibliográfico, na qual foram explorados padrões de codificação, modelos conceituais e de estruturação de dados bibliográficos, destacando-se o BIBFRAME, RDA, RDF e o OWL, os quais foram combinados para definir uma nova abordagem teórico-metodológicas denominada de Heredograma Informacional, com aplicação em documentos e textos provenientes de fontes de informações da WEB e também provenientes de conhecimento registrado, típico de unidades de informação. Foi obtido como resultado uma proposta que possui propriedades de uma estrutura taxonômica que também produz informação verificável a respeito dos documentos e seus respectivos conteúdos. Nela considera-se a atribuição de um Identificador Semântico de Objeto Digital (ISOD) a ser utilizado em associação ao DOI ou em substituição a este. O Heredograma Informacional prevê a incorporação de elementos funcionais ativos para a produção automática, com ou sem supervisão humana, de elementos semânticos extraídos dos conteúdos dos documentos. A proposta produzida como resultado dos trabalhos introduz elementos para a mitigação dos problemas relacionados à desinformação e a fake news e adiciona elementos provenientes do processamento de linguagem natural (PLN), inteligência computacional (IC) e inteligência artificial (IA).
Análise da Percepção das Bibliotecas Nacionais Latino-Americanas sobre Depósito Legal, Controle Bibliográfico e Bibliografias e Comparação com a Percepção das Bibliotecas Nacionais Ibéricas
Authors: Dos Santos Drummond Xavier Aline , Alvarez Gonzalo Rubén
Published: March 2024

Analisa a percepção das bibliotecas nacionais latino-americanas sobre a situação atual do depósito legal e controle bibliográfico e a importância da formação e manutenção de bibliografias correntes e atualizadas para a preservação da memória, identidade e patrimônio intelectual nos países que representam, comparando-a com a percepção das bibliotecas nacionais ibéricas. Trata-se de uma pesquisa exploratória e descritiva, de abordagem quali-quantitativa. Como instrumento de coleta de dados, utilizou-se um questionário on-line, composto de perguntas abertas e fechadas. O corpus é constituído por 12 bibliotecas nacionais respondentes (11 latino-americanas e 01 ibérica), representando 55,0% e 50,0% dos países levantados respectivamente. De modo geral, os resultados mostram que, apesar da boa vontade das bibliotecas nacionais latino-americanas respondentes, ainda são necessárias diversas ações para tornar o depósito legal e controle bibliográfico totalmente eficiente e representativo. Embora o uso de bibliografias retrospectivas seja percebido como importante para a disseminação da produção intelectual, o cenário está longe de ser o ideal, haja vista a diversidade de fatores apontados que impactam negativamente na formação e manutenção de bibliografias correntes e atualizadas. A situação é diferente na biblioteca nacional ibérica respondente, o que pode simbolizar um reflexo de iniciativa bem-sucedida permeada pela maior tradição cultural de preservação documental do país que representa quando comparada à dos países latino-americanos.
Hernán Borisonik. Persistencia de la pregunta por el arte || Valentín Díaz. Tensión y materia
Authors: Buljančević Rastko , López Nicolás
Published: March 2024

Hernán Borisonik. Persistencia de la pregunta por el arte. Buenos Aires: Miño y Dávila, 2022, 132 páginas.
Valentín Díaz. Tensión y materia. El método del Barroco en Walter Benjamin. Buenos Aires: 17grises, 2023, 456 páginas.
In-hospital metrics for the Treatment of Cervical Cancer in Minas Gerais in 2021 – Time Series from 2012 to 2021.
Authors: Martins Rubatino Fernando Victor , Pereira Lopes Isabela Louise ,  Lazarotti Mariana de Paula ,  Loureiro Rubatino André Lucas , René Hoelzle Carolina  , Fonseca Costa de Alvarenga Érika Lorena , Alves Costa Raquel  , Knopp Priscylla Liliam
Published: March 2024

Cervical cancer (CC) is the third most common tumor in the female population. Due to the importance of its morbimortality, public health policies have been developed in Brazil since the mid-1980s. It is decisive to detect lesions in early stages for the prognosis and conduct to be adopted, so that lesions in a more advanced stage, usually require more invasive procedures and hospital admissions. In spite of prevention and control measures currently adopted, it is important to monitor prevalence rates of hospital procedures for cervical cancer and its lethality, with the purpose of contributing to the planning of prevention actions. OBJECTIVE: To describe the frequency of hospital procedures for CC in Minas Gerais, and to observe their trend from 2012 to 2021. METHODS: The present work consists of a descriptive, ecological, observational study of hospital procedures for CC in Minas Gerais in 2021; and an analytical study from 2012 to 2021. RESULTS AND DISCUSSION: In Minas Gerais in 2021, 2,122 hospital procedures were performed due to CC. The most common age group was from 35- to 44-year-olds, followed by 45- to 54-year-olds. Of the total number of procedures, hospital admissions to treat cancer patients was the most common one followed by two other clinical procedures. The analysis of this time series has shown a significant decrease when procedures were observed globally (all age groups) and for 35-to-44-year-olds and 45-to-54-year-olds. CONCLUSION: In spite of the improvement trend of some indicators, when observing this time series, these indicators need to be continually monitored so that the real impacts of the proposed actions to improve the general scenario are verified, and especially the age groups who have not shown reduced rates. Interventions should be considered not only in health, but those that also cover socioeconomic and humanitarian indicators.
Factors Associated with Unsuccessful Treatment of Bedaquiline and or Delamanid Based Regimens in Multidrug-Resistant Tuberculosis: A Review
Authors: Nugraha Putra Oki , Faizah Ana Khusnul , Wijayanti D.N Nani
Published: March 2024

Background: Multidrug-resistant tuberculosis (MDR-TB) is a serious health concern that is difficult to treat, requiring long and complex treatment with highly effective drugs. An all-oral regimen, bedaquiline and or delamanid have already shown low unsuccessful treatment in patients with MDR-TB. Method: We comprehensively reviewed factors associated with unsuccessful treatment (death, treatment failure, and loss to follow-up) related to all oral regimen containing bedaquiline and or delamanid in patients with MDR-TB. We conducted a scoping review under the PRISMA guideline for scoping review. Results: We included seven observational studies that met the inclusion criteria. Four studies reported the concomitant use of bedaquiline and delamanid. Unsuccessful treatment ranged from 7.8% to 36.6% in regimens containing bedaquiline, delamanid, or both at six months or after treatment completion. Low rates of treatment failure and loss to follow-up were reported in the included studies. Elderly, being underweight (BMI < 18.5 kg/m2), and hepatitis C coinfection among MDR-TB patients were associated with unsuccessful treatment in most studies. None studies reported pre-XDR and XDR-TB as risk factors for unsuccessful treatment. Conclusion: In MDR-TB patients receiving regimens containing bedaquiline and delamanid, age, BMI, and hepatitis C coinfection were associated with unsuccessful treatment.
Effect of Biochanin-A on The Cerebellum in Cerebral Ischemia Reperfusion Injury
Authors: AVINCA Öner , KAPLAN Özge , AŞIR Fırat
Published: March 2024

ABSTRACT

Objective: To examine the protective effect of Biochanin A (BCA) on the cerebellum in cerebral ischemia reperfusion injury.
Material and Metodhs: 24 Wistar albino female rats were divided into 3 groups. Control, Ischemia reperfusion (IR), IR +BCA (20 mg/kg intraperitoneal) group. A micro bulldog clamp was placed on the left common carotid artery of the rats and cerebral ischemia was applied for 2 hours. After cerebral ischemia, the clamp was removed and reperfusion was performed for 24 hours. After 7 days, all rats were decapitated and the protective effects of Biochanin A on the cerebellum were evaluated by immunohistochemically analyses.
Results: In the IR group; S100 expression was also observed positive in neurons and neuroglia in the pia mater, molecular layer, Purkinje cells in the ganglionic layer and granule cells in the granular layer, and neuroglia in the white matter. In the IR+ Biochanin A group, it was observed that the immune activity in the granule cells and Purkinje cells in the granular layer was reduced compared to the IR group.
Conclusion: We suggest that Biochanin A treatment has a potential therapeutic role in alleviating inflammation in the cerebellum after cerebral ischemia reperfusion.
Abordagem no Tratamento da Síndrome do Intestino Irritável: Modulação da Microbiota e Medicamentos Específicos
Authors: Silva Bueno Larissa Fernanda , Soares Aragão José Henrique , Tobias da Silva Ana Beatriz , Dias do Nascimento Brenda , Jahel Meireles Danilo
Published: March 2024

Nesta análise, são examinadas várias estratégias terapêuticas para o tratamento da Síndrome do Intestino Irritável (SII), com foco na modulação da microbiota e no uso de medicamentos específicos. Inicialmente, destacamos a eficácia das intervenções farmacológicas recentes desenvolvidas, enfatizando sua capacidade de controlar os sintomas da SII e melhorar a qualidade de vida dos pacientes. Essas terapias emergentes não se limitam apenas ao alívio dos sintomas, mas também buscam abordar as causas subjacentes da condição, levando em consideração a complexa interação entre a microbiota intestinal e fatores ambientais.

Além das intervenções farmacológicas, estão sendo exploradas abordagens inovadoras, como a modulação da microbiota intestinal, que visa restaurar o equilíbrio da flora intestinal afetada na SII. Essas estratégias incluem o uso de probióticos, prebióticos e simbióticos, que demonstraram promover a saúde intestinal e reduzir os sintomas da SII em alguns pacientes. A pesquisa contínua nesse campo é crucial para identificar as cepas microbianas mais eficazes e entender melhor como elas podem beneficiar os indivíduos com SII.

Além disso, é importante destacar o papel dos medicamentos específicos no tratamento da SII, incluindo agentes antiespasmódicos, moduladores da motilidade intestinal e agentes reguladores da dor visceral. Esses medicamentos visam aliviar os sintomas gastrointestinais, como dor abdominal, distensão e alterações no trânsito intestinal, proporcionando alívio aos pacientes afetados pela SII.

Em resumo, a abordagem no tratamento da Síndrome do Intestino Irritável está cada vez mais focada na modulação da microbiota e no uso de medicamentos específicos. A integração dessas estratégias terapêuticas pode oferecer uma abordagem mais abrangente e personalizada para o manejo da SII, melhorando significativamente a qualidade de vida dos pacientes. No entanto, são necessárias mais pesquisas para entender completamente os mecanismos subjacentes e otimizar o uso dessas intervenções terapêuticas na prática clínica.
Procedimentos Cirúrgicos para o Tratamento da Incontinência Urinária: uma análise abrangente
Authors: Spíndola Silva Luísa , de Melo Eufrásio Moura Lucas , Caldeira Vasconcelos Souza Filipe , Fernandes Lopes de Almeida Guilherme , de Moura Campos Torga Vitoria
Published: March 2024

Nesta análise, são explorados diferentes procedimentos cirúrgicos para o tratamento da incontinência urinária, abordando uma variedade de técnicas e abordagens cirúrgicas inovadoras. Inicialmente, destaca-se a eficácia dos procedimentos de sling, os quais envolvem o uso de materiais sintéticos ou biológicos para dar suporte à uretra e restaurar a continência urinária. Esses procedimentos têm demonstrado resultados promissores na redução dos sintomas de incontinência e na melhoria da qualidade de vida dos pacientes.

Além dos procedimentos de sling, são discutidas as técnicas de colposuspensão, as quais envolvem a fixação cirúrgica da uretra e da bexiga aos tecidos circundantes para restaurar a continência. Embora esses procedimentos tenham sido tradicionalmente utilizados, sua eficácia a longo prazo e sua segurança continuam sendo áreas de investigação em evolução.

Outro aspecto importante é a crescente adoção de procedimentos minimamente invasivos, como a terapia com laser e a neuroestimulação sacral, os quais visam modular as vias neurológicas envolvidas no controle da bexiga. Essas técnicas oferecem a vantagem de menor tempo de recuperação e menor morbidade, tornando-as opções atrativas para muitos pacientes.

Além das intervenções cirúrgicas, enfatiza-se a importância de uma abordagem multidisciplinar no tratamento da incontinência urinária. Isso inclui a colaboração entre urologistas, fisioterapeutas pélvicos e especialistas em medicina comportamental para fornecer uma abordagem abrangente e personalizada para cada paciente.

Em resumo, os procedimentos cirúrgicos continuam a desempenhar um papel crucial no tratamento da incontinência urinária, oferecendo opções eficazes para aqueles que não respondem ao tratamento conservador. No entanto, é essencial uma avaliação cuidadosa do paciente e uma abordagem individualizada para garantir os melhores resultados e a satisfação do paciente a longo prazo.
TOXICIDADE CARDIOLÓGICA POR ANTRACICLINAS APÓS TRATAMENTO DE LEUCEMIA AGUDA EM CRIANÇAS: revisão integrativa
Authors: Costa Lucas Manoel Oliveira , Izane Luisa Xavier Carvalho Andrade  , Maria Belquiane Carvalho Pereira  , Rithielly nayara da Silva Sousa  , Antonio Tito de Araujo Dantas  , Marcelo da Silva Sousa  , Marcus Vinicius de Carvalho  Souza  , Ana Paula Laranjeiras De Melo  , Jordeilson Luis Araujo Silva  , Lisiane Pires Martins dos Santos
Published: March 2024

O presente estudo visa discutir as evidências científicas sobre a cardiotoxicidade em crianças após tratamento  de Leucemia Linfóide Aguda por antraciclinas. Estudo  do  tipo  revisão  integrativa  da  literatura, associado ao acrônimo PICo e estruturado com os descritores: Cardiotoxicidade, Antraciclinas, Leucemia-Linfoma Linfoblástico de Células Precursoras, no recorte temporal de 2017 a 2022, sendo desenvolvido por meio das bases de dados: Literatura Latino-americana e do Caribe em Ciências da Saúde (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE), e Scientific Electronic Library Online (SciELO). O emprego das antraciclinas e seus derivados têm elevado a taxa de sobrevida dos pacientes oncológicos pediátricos. A cardiotoxicidade está descrita como um dos efeitos colaterais mais comuns nessa população, no entanto as pesquisas desenvolvidas demonstram que a modificação dos protocolos terapêuticos buscam reduzir os eventos cardiovasculares indesejáveis.
Using the initial parameters method to calculate the deformation of disks of power machines
Authors:   Nesterenko G.A. Nesterenko I.S.
Published: March 2024

The calculation of deflections of disks of power machines is considered based on the principles of the elasticity theory of round plates using the method of initial parameters. It is proposed to replace the axial fixing with radial one. The basic equations for calculating disc deflections are given.

Keywords
disk, force, fixing, deflection, processing accuracy, initial parameters method
Development, design and calculation of structural and technological parameters of the root crop feeder-dispenser
Authors:   Brusenkov A.V. Konovalov D.N.
Published: March 2024

The design of a feeder-dispenser for root crops is developed, ensuring the preparation of root crops for subsequent processing. Analytical expressions are obtained that reflect the dependencies of the operational energy indicators of the feeder-dispenser and the rheological properties of the processed feed on the main design parameters of the device.

Keywords
feeder-dispenser, design, root crops, calculation
Estimation of the temperature of the ductile-brittle transition of aluminum matrix composite materials at negative temperatures using classification of acoustic emission signal pulses
Authors:   Anosov M.S. Shatagin D.A. Romanov A.D. Romanova E.A. Makarov V.S.
Published: March 2024

The results of experiments on assessing the mechanical properties, in particular the temperature of the ductilebrittle transition of aluminum matrix composite materials at negative temperatures using the classification of acoustic emission signal pulses, are presented. It is established that this transition is absent at temperatures down to –100 °C and, therefore, it is possible to use aluminum matrix composite materials for the manufacture of suspension elements for equipment operating in Arctic and Antarctic conditions.

Keywords
aluminum matrix composite materials, mechanical properties, temperature, ductile-brittle transition
Cutup milling
Authors:   Babin S.V. Ignatov M.G. Perminov A.E.
Published: March 2024

Cutup milling of flat surfaces is investigated. It is established that to improve the accuracy of machined surfaces, it is necessary to take into account the cutting force vector, which depends on the cutting depth and the diameter of the cutter.

Keywords
cutup milling, machining, quality, cutting force vector, mill deformation
Determination of rational regulations of diesel engine fuel supply equipment when working on biomineral fuel mixtures
Authors:   Plotnikov S.A. Kartashevich A.N. Zabolotskih G.E.
Published: March 2024

The object of research is an experimental installation consisting of a D-245.5S2 diesel engine and a RAPIDO SAK N670 electric brake stand for operation on pure diesel fuel and on multicomponent biomineral fuel mixtures (BMFM): BMFM-10, BMFM-25.
The research objective is to study the effect of different content of additives of Barbarйa vulgбris oil and ethanol in BMFM on effective and toxic indicators.
The purpose of the study is to determine the rational adjustments of the fuel pump YAZDA-773-40.28 diesel D-245.5S2 when it is operated on BMFM-10, BMFM-25.
Research methods — experimental testing by conducting bench tests according to GOST 18509—88.

Keywords
fuel injection pump, setting angle of fuel injection advance, Barbarйa vulgбris oil, ethanol, diesel fuel, biomineral fuel mixture (BMFM), effective indicators, environmental indicators
Correlação entre Ecocardiografia POCUS Guiada por Telemedicina e Dados In Situ: Estudo Piloto em uma Região Remota no Brasil
Authors: Rompkoski Juliane , Accorsi Tarso Augusto Duenhas , Amaral Bruna Dayanne Reges , Freitas Christian Barbosa de , Moreira Flavio Tocci , Kohler Karen Francine , Lima Karine De Amicis , Morbeck Renata Albaladejo , Pedrotti Carlos Henrique Sartorato
Published: March 2024

As doenças cardiovasculares continuam sendo a principal causa de mortalidade no Brasil. No entanto, uma parcela significativa da população ainda enfrenta dificuldades no acesso a cuidados especializados e na realização de exames complementares, especialmente em regiões mais remotas. Apesar da existência de transmissão de dados e avaliação remota especializada, a obtenção de imagens ecocardiográficas ainda depende da presença de um profissional treinado no local. Este estudo piloto teve como objetivo avaliar a viabilidade da tele-ecocardiografia por Ultrassom no “Point of Care” (local de atendimento), na sigla, em inglês, “POCUS”, administrada por um médico generalista com orientação especializada, visando melhorar a acessibilidade aos exames cardiovasculares. Participaram deste estudo dez pacientes (cuja média de idade era 56,6+8 anos, 50% pacientes do sexo feminino) da região Norte, submetendo-se a exames guiados remotamente utilizando o ultrassom Philips Lumify™ e a plataforma Facetime para transmissão. Esses pacientes já haviam realizado exames ecocardiográficos oficiais recentes. Durante o exame POCUS, foram obtidas sete incidências ecocardiográficas, incluindo eixo longo paraesternal, eixo curto paraesternal, apical de quatro câmaras (A4C), apical de cinco câmaras (A5C), apical de duas câmaras (A2C), subcostal (SC) e supraesternal (SSN). O procedimento incluiu medidas lineares das câmaras cardíacas, e a análise valvar foi realizada por meio de fluxometria colorida. Os exames presenciais foram conduzidos por um clínico geral que recebeu um treinamento breve antes dos exames oficiais. Apesar dos desafios técnicos, o estudo demonstrou a viabilidade da aquisição de imagens ecocardiográficas, com concordância geral nos resultados dos exames, exceto em dois casos relacionados à contratilidade segmentar e ao diâmetro sistólico do ventrículo esquerdo. A abordagem, mesmo conduzida por profissionais não especializados, mostrou-se promissora no rastreamento de doenças cardiovasculares em locais remotos, com foco na função ventricular e nas doenças valvares. Contudo, são necessárias mais pesquisas para aprimorar a qualidade desse processo.
Ethical Dilemmas in Modern Business Management
Authors: Parul
Published: March 2024

The landscape of modern business management is constantly changing. One of the most important and complicated aspects of this landscape is the emergence of ethical issues. This paper sheds light on the numerous decisions that constitute the ethical landscape of contemporary business and the varied arena of ethical dilemmas addressed by companies. It is no longer the case that conventional moral conundrums are the only types of ethical dilemmas that might arise in business management. They also include a broad range of concerns, ranging from environmental sustainability to the protection of personal information and the concept of social responsibility.
ВЛИЯНИЕ АДСОРБЦИОННОЙ СПОСОБНОСТИ АКТИВИРОВАННОГО УГЛЯ В СОСТАВЕ ПИТАТЕЛЬНОЙ СРЕДЫ НА ПРИЖИВАЕМОСТЬ И МОРФОГЕНЕЗ ИЗОЛИРОВАННЫХ ТКАНЕЙ КАРТОФЕЛЯ IN VITRO
Authors: Собралиева Э.А. , Джамаева А.Ю. , Башуева А.М.
Published: March 2024

Были предприняты попытки изучения адсорбционных свойств активированного угля в составе питательных сред картофеля на этапе введения в культуру in vitro. Потенциал сельскохозяйственного применения культуры растительных клеток для улучшения урожая поразителен. Даже если использовать только менее технический метод регенерации растений меристемной культуры для клонирования и генетической изменчивости, культура растительных клеток должна оказать огромное влияние на улучшение урожая в ближайшем будущем.
Результаты исследований свидетельствуют об эффективности добавления в состав питательной среды активированного угля на этапе введения в стерильную культуру в концентрации 10 г/л; при этой концентрации максимально проявляется адсорбционная способность этого вещества, также стоит отметить эффективность его сочетания с цитокининным регулятором роста растений 6-БАП (5 мг/л). Кроме того, среди исследуемых сортов наибольшей приживаемостью и высокими показателями биометрии в культуре in vitro отмечен сорт Арроу.
ПРИМЕНЕНИЕ СУБСТРАТОВ И БИОСТИМУЛЯТОРА КОРНЕОБРАЗОВАНИЯ «КОРНЕВИН» ПРИ УКОРЕНЕНИИ ЗЕЛЕНЫХ ЧЕРЕНКОВ ВИШНИ
Authors: Титова Л.А. , Макарова А.Г. , Магомадов С.А.
Published: March 2024

Корнесобственные саженцы вишни обыкновенной получают самыми различными методами, к основным относят микроклональное размножение, размножение корневыми черенками (порослью), одревесневшими черенками и укоренение зелеными черенками. В практике садоводов наибольшее распространение получил метод зеленого черенкования. Основа методики зеленого черенкования под собой подразумевает выращивание полноценных вишневых саженцев из молодых побегов этого года (до 10 сантиметров длиной), взятых от маточного растения. Погодно-климатические и почвенные условия условного региона не оказывают непосредственного влияния на технологию выращивания зеленого черенка, поскольку весь этот процесс протекает в контролируемых условиях закрытого грунта, что позволяет повысить коэффициент размножения и увеличить выход укоренившихся черенков вишни с единицы эксплуатируемой площади.
ИННОВАЦИОННЫЕ МЕТОДЫ ДИАГНОСТИКИ ЗАБОЛЕВАНИЙ ЖИВОТНЫХ
Authors: Абдулхажиева А.Ш. , Абдулхажиева М.Ш.
Published: March 2024

В современной медицине и ветеринарии уже не представляется возможным исследование пациентов без специализированного оборудования. В данной статье мы рассмотрим, какие инновационные методы диагностики заболеваний животных существуют в ветеринарии. В наше время не представляется возможным лечение животных без инструментальной диагностики. Одним из примеров такого оборудования является аппарат ультразвукового исследования (УЗИ), который стал активно применяться для постановки точного диагноза при многих заболеваниях животных. Рентген является достаточно распространённым методом диагностики, дающим возможность получить высокоинформативные данные за максимально короткий промежуток времени. Позволяет диагностировать различные заболевания и патологии, контролировать ход их изменений в процессе лечения. Рентген не требует специальной подготовки и проводится без вмешательства в организм животного.
Entrevista - PROJETO ARARA AZUL - MONITORAMENTO E MANEJO DE UMA ESPÉCIE EM EXTINÇÃO
Authors: Guedes Neiva Maria Robaldo
Published: March 2024

Entrevista realizada com a Dra. Neiva Maria Robaldo Guedes que discorreu sobre o Instituto Arara Azul, decrevendo as atuações do mesmo, bem como todas as ações realizadas no projeto para monitoramento e conservação desta espécie em extinção. Além disso, a Dra. Neiva abordou aspectos de sua trajetória como pesquisadora e a importância da educação ambiental.
PENGARUH PENGETAHUAN INVESTASI DAN LITERASI KEUANGAN TERHADAP KEPUTUSAN INVESTASI PADA NASABAH BANK JATIM JEMBER DENGAN INKLUSI KEUANGAN SEBAGAI VARIABEL INTERVENING
Authors: Bastarani Penny Siska , Karnadi Karnadi , Fandiyanto Randika
Published: March 2024

The research objective is to determine the effect of investment knowledge and financial literacy on investment decisions for customers of Bank Jatim Jember with financial inclusion as an Intervening variable. Abdurachman Saleh University, Situbondo. The sampling technique used in this study was simple random sampling using the Slovin formula with a tolerable error rate of 10% for 96 customers. Data analysis and hypothesis testing in this study used the Structural Equation Model - Partial Least Square (PLS-SEM)The results of the direct effect hypothesis test using the Smart PLS 3.0 application, show that investment knowledge has a positive and significant effect on financial inclusion, financial literacy has a positive and significant effect on financial inclusion, investment knowledge has a positive and significant effect on investment decisions, financial literacy has a negative and insignificant effect on investment decisions, financial inclusion has a positive and significant effect on investment decisions, investment knowledge has a positive and significant effect on investment decisions through financial inclusion, financial literacy has a positive and significant effect on investment decisions through financial inclusion.
PENGARUH PERCEIVED VALUE DAN KUALITAS PELAYANAN TERHADAP KEPUTUSAN PEMBELIAN MELALUI KEPUASAN KONSUMEN SEBAGAI VARIABEL MEDIASI PADA TOKO JAKARTA CLOTH SITUBONDO
Authors: Zaufariyanto Abdul Malik , Soeliha Siti , Praja Yudha
Published: March 2024

The research objective is to determine the effect of perceived value and service quality on purchasing decisions through consumer satisfaction as a mediating variable at the Jakarta Cloth Situbondo store. The sampling technique used in this study was simple random sampling of 98 consumers. Data analysis and hypothesis testing in this study used the Structural Equation Model - Partial Least Square (PLS-SEM).

The results of the direct influence hypothesis test using the Smart PLS 3.0 application, show that Perceived value has a positive and significant effect on consumer satisfaction, service quality has a positive and significant effect on consumer satisfaction, perceived value has a positive and significant effect on purchasing decisions, service quality has a negative but not significant effect on purchasing decisions, consumer satisfaction has a positive and significant effect on purchasing decisions, perceived value has a positive but not significant effect on purchasing decisions through consumer satisfaction, service quality has a positive and significant effect on purchasing decisions through consumer satisfaction.