bluuebunny/crossref_metadata_2025 huggingface dataset:
Peningkatan Taraf Hidup Melalui Produksi Pupuk di Pondok Pesantren Mahad Nurul Haromain Jawa Timur
Authors:   Sekolah Tinggi Ilmu Ekonomi Indonesia (STIESIA) Surabaya, Jl. Menur Pumpungan No. 30, Kec. Sukolilo, Surabaya, Jawa Timur 60118, Indonesia, Lestariningsih Marsudi , Widi Oetomo Hening ,   Sekolah Tinggi Ilmu Ekonomi Indonesia (STIESIA) Surabaya, Jl. Menur Pumpungan No. 30, Kec. Sukolilo, Surabaya, Jawa Timur 60118, Indonesia, Muhyi Muhyi ,   Universitas 17 Agustus 1945 Surabaya, Jl. Semolowaru No.45, Kec. Sukolilo, Surabaya, Jawa Timur 60118, Indonesia
Published: October 2022

Pertumbuhan ekonomi Jawa Timur sekitar 3,4 % pertahun tidak mampu mengatasi persoalan pengangguran, karena jumlah angkatan kerja terus bertambah setiap tahun. Dampaknya terasa pada pondok pesantren yang berada di Jawa Timur, yang berakibat lulusannya sulit untuk mendapatkan pekerjaan, karena dari segi iptek dan keterampilannya belum memadai. Sekolah Tinggi Ekonomi Indonesia (STIESA), atas permintaan dari pihak pondok pesantren, membantu menyelesaikan masalah limbah peternakan dan sampah yang ada di lingkungan pondok pesantren dengan memanfaatkannya. Cara yang diusulkan dan dipraktikkan adalah mengolah limbah dan sampah tersebut menjadi produk pupuk dengan teknologi tepat guna.
Meningkatkan Keunggulan Bersaing Melalui Analisis SWOT
Authors:   Universitas Muhammadiyah Sumatera Utara Jl. Kapten Mukhtar Basri, No. 3, Medan 20238, Sumatera Utara, Indonesia, Arda Mutia
Published: October 2022

Tujuan penelitian ini adalah untuk mencari berbagai alternative strategi yang tepat dalam pemasaran melalui berbagai pertimbangan diantaranya STP (Segmenting, Targeting dan Positioning), bauran pemasaran 4 P (Product, Price, Place, Promotion) dan analisis SWOT (Strength, Weakness, Opportunity dan Threat) dalam hal ini adalah produk Batik Medan. Teknik analisa data yang digunakan adalah Matriks Faktor Strategi Internal (IFAS), Matriks Faktor Strategi Eksternal (EFAS) dan Matriks SWOT (Strength, Weakness, Opportunities, Threats). Hasil penelitian menunjukkan bahwa pengrajin Batik Medan berada dalam situasi yang sangat baik karena ada kekuatan yang dimanfaatkan untuk meraih peluang yang menguntungkan. Untuk itu dapat digunakan alternatif strategi 1 yakni pengembangan (strategi agresif).
Pengaruh Promosi Media Situs Jual Beli Online Terhadap Peningkatan Penjualan Produk UKM
Authors:   IKPIA Perbanas, Jalan Perbanas, Karet Kuningan Setiabudi, Jakarta 12940, Sovania Erina , Selliamanik Irma ,   IKPIA Perbanas, Jalan Perbanas, Karet Kuningan Setiabudi, Jakarta 12940
Published: October 2022

SME products are small and medium scale local industries that must be intensely supported by their development because these local products can raise the standard of living of people in a suburban area of ​​a large or rural city to become an independent community. This study aims to open up a broad view that for SME products it is necessary to carry out extensive sales promotions so that their products can be well-known and sales can penetrate a wider market. The research conducted is to conduct quantitative research methods, with data collection methods through questionnaires and interviews through respondents as many as 50 online shops in bukalapak.com then the data is processed and analyzed using Pearson Product Moment Correlation (PPM) data analysis techniques to determine how big is the relationship, the Determinant Coefficient to find out the contribution of the X variable to the Y variable and the Significance Test to find out the Meaning of the Relationship in both variables, and linear regression. From the results of this study it was found that the promotion of online media buying and selling sites has a strong relationship and has a high influence on the increase in sales of SME products. Where obtained PPM correlation (relationship) of 0.75 included in the criteria for a strong relationship, and the coefficient of determinant which means that the contribution of variable X to Y has a high or strong influence, and the significance test with interpretation has the meaning of an influential relationship, and with linear regression that is y = 0.5467x - 3.4702.
Identifying Ultimate Controlling Shareholders In Indonesian Public Companies: an Empirical Survey
Authors:   Indonesian Institute of Family Firm (IIFF) - Universitas Islam Indonesia, Sobirin Achmad , Fahruddin MZ. ,   Indonesian Institute of Family Firm (IIFF) - Universitas Islam Indonesia, Rosid Andiana ,   Indonesian Institute of Family Firm (IIFF) - Universitas Islam Indonesia
Published: October 2022

This paper aims to identify the ultimate ownership of public companies that are listed on the Indonesia Stock Exchange (IDX) during 2014-2017 period. Identification techniques used in this study are: (1) tracking the ownership structure; (2) measuring the level of control; (3) determining the majority ownership, and (4) finding the ‘controlling shareholder’ narrative in the annual report. Based on tim research analyze, this paper found that the ultimate ownership of public companies in Indonesia 2014-2017 was concentrated in the ultimate family owners (54.43%), corporations (31.05%) and the state (7.49%). Beside it, 89.43% of families use the indirect ownership structure (pyramid ownership). In addition, more than 50% of the ultimate family ownership place their family members in the Board of Commissioner (BOC) and Board of Directors (BOD).
Pengaruh Kualitas Produk, Kualitas Layanan, dan Citra Merek Terhadap Loyalitas Melalui Kepuasan
Authors:   Fakultas Ekonomi dan Bisnis Universitas Pembangunan Nasional Veteran Jakarta, Kasturi Diana , Suharyati Suharyati ,   Fakultas Ekonomi dan Bisnis Universitas Pembangunan Nasional Veteran Jakarta, Nastiti Heni ,   Fakultas Ekonomi dan Bisnis Universitas Pembangunan Nasional Veteran Jakarta
Published: October 2022

comThis research aims to know product quality, service quality, brand image, with satisfaction as intervening variabel toward loyalty. The problem of research is the large amount of batik imports in Indonesia. The sample in this study amounted to 50 users and customers Batik Betawi Terogong products in West Cilandak, South Jakarta. Sampling is done by using Purposive Sampling. This research uses PLS (Partial Least Square). The results of this study showed that product quality variables have significant influence on loyalty but have no significant influence on loyalty through satisfaction. Service quality have no significant influence on loyalty and also have no significant influence on loyalty through satisfaction. Brand image have significant influence on loyalty, but have no significant influence on loyalty through satisfaction and satisfaction have significant influence on loyalty. Therefore it is expected Batik Betawi Terogong can improve product quality, service quality, and brand image and maintain the satisfaction to be created loyalty to customers.
Perilaku Konsumen terhadapPenggunaan Kantong Plastik dan Tas Kain di Area Jabodetabek
Authors:   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, A.C Ginting , G Pratiantono ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, G Ruseffi ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, J.F. Turnip ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, M Rhesa ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya
Published: October 2022

Penelitian bertujuan untuk menguji Theory of Planned Behavior dalam konteks keinginan individu dalam mengurangi penggunaan kantong plastik, yaitu hubungan antara kesadaraan lingkungan, tekanan sosial, dan dukungan pelarangan penggunaan kantong plastik terhadap keinginan menggunakan tas kain (totebag) oleh individu yang tinggal dan pernah berbelanja supermarket di wilayah Jabodetabek. Tiga variabel yang mempengaruhi keinginan individu dalam menggunakan tas kain adalah, kesadaran lingkungan, tekanan sosial, dukungan terhadap pengurangan penggunaan kantong plastik. Kemudian pengaruh keinginan individu dalam menggunakan tas kain terhadap perilaku atau kebiasaan dalam mengurangi penggunaan kantong plastik. Kuesioner dilakukan dengan metode kuantitatif dan diadaptasi dari penelitian sebelumnya. Kuesioner diberikan kepada responden yang berada di wilayah Jabodetabek. Sebanyak 315 kuesioner terkumpul, kemudian dilakukan analisis menggunakan analisa regresi berganda untuk menguji kesadaran lingkungan, tekanan sosial, dukungan larangan penggunaan kantong plastik terhadap keinginan menggunakan kantong kain, serta pengaruhnya terhadap perilaku dalam mengurangi penggunaan kantong plastik di Jabodetabek. Kesadaran lingkungan, tekanan sosial, dukungan larangan penggunaan kantong plastik terbukti berpengaruh terhadap keinginan dalam menggunakan tas kain. Sementara keinginan dalam menggunakan tas kain berpengaruh signifikan terhadap perilaku dalam mengurangi penggunaan kantong plastik di Jabodetabek
Adopsi Teknologi Jasa Pesan Antar Makanan Online di Kalangan Perempuan Pedagang Kuliner pada Masa Pandemi Covid-19
Authors:   Departemen Manajemen, Fakultas Ekonomi dan Bisnis Universitas Airlangga, Siwi Agustina Tri
Published: October 2022

Social distancing dan physical distancing dalam rangka memutus rantai penyebaran Covid-19 berdampak pada eksistensi usaha yang dimiliki para perempuan pedagang kuliner di 39 Sentra Wisata Kuliner di Surabaya. Penelitian ini bertujuan untuk mengetahui niat untuk menggunakan (use intention) para perempuan pedagang kuliner di Kota Surabaya dalam mengadopsi Grabfood dan GoFood sebagai solusi untuk mempertahankan kinerja usahanya di masa pandemi Covid-19. Jenis penelitian yang dilakukan adalah penelitian kuantitatif deskriptif. Sebanyak 302 perempuan pedagang kuliner yang telah menggunakan kedua aplikasi jasa pesan antar makanan tersebut diberikan kesempatan yang sama untuk mengisi kuesioner sehingga teknik pengambilan sampel yang digunakan disebut sebagai sampel jenuh (sensus). Pengujian hipotesis dilakukan dengan menggunakan SmartPLS Versi 3.2.9 Hasil penelitian yang diperoleh adalah behaviour intention untuk mengadopsi GoFood dan Grabfood di kalangan perempuan pedagang kuliner di Kota Surabaya terbukti dipengaruhi harapan akan kinerja (performance expectancy), harapan akan usaha (effort expectancy), pengaruh sosial (social influence). Akan tetapi kondisi pendukung (facilitating condition) terbukti tidak berpengaruh pada niat untuk berperilaku (behavior intention). Hasil lain adalah niat untuk berperilaku terbukti berpengaruh pada niat untuk menggunakan GoFood dan Grabfood di kalangan perempuan pedagang kuliner di Surabaya selama pandemi Covid-19.
Rancangan Layanan Kedai Kopidengan Dimensi Service Quality danImportance Performance Analysisdi Masa Pandemi Covid-19
Authors:   Departemen Manajemen,Fakultas Ekonomi dan Bisnis Universitas Airlangga, Muhammad Dynoviar Nirbita , Wurjaningrum Febriana ,   Departemen Manajemen,Fakultas Ekonomi dan Bisnis Universitas Airlangga
Published: October 2022

Turunnya pendapatan akibat COVID-19 serta anjuran protokol kesehatan dari pemerintah membuat pelaku bisnis mencari cara yang efektif untuk dapat melayani secara maksimal dengan segala keterbatasan pada masa pandemi. Dimensi Service Quality dan metode Importance Performance Analysis (IPA) dapat membantu pelaku bisnis menemukan atribut yang dapat diperbaiki berdasarkan nilai kinerja dan nilai kepentingan. Peneliti membuat 22 pertanyaan seputar kualitas layanan di masa pandemi berdasarkan studi pustaka. Terdapat 65 partisipan yang diambil dari pelanggan kedai selama pandemi COVID-19. Menurut hasil IPA, usulan perbaikan dapat diterapkan pada dimensi Servqual yang masuk ke dalam Kuadran I (Prioritas Utama). Di dalamnya antara lain terdapat atribut protokol kesehatan sesuai anjuran pemerintah, ruang duduk yang nyaman dan memadai, serta ruang duduk yang bersih dan rapi. In-depth interview kemudian dilakukan dengan manajer dan pemilik Kedai Kopi Berbaur untuk menemukan usulan perbaikan. Usulan perbaikan yang dihasilkan antara lain adalah penempelan informasi physical distancing, perluasan tempat di masa sewa selanjutnya, dan melakukan pengawasan berkala terhadap kinerja kebersihan tempat. Hasil penelitian ini menambah bukti empiris dan referensi mengenai praktik yang berkaitan dengan kualitas pelayanan dalam bisnis kedai kopi pada masa pandemi COVID-19
Perumusan Strategi Pengembangan Bisnis Bebys Coffee Menggunakan Analisis Swot dengan Neutrosophic Analytic Hierarchy Process
Authors:   Departemen Ilmu Manajemen, Fakultas Ekonomi dan Bisnis,Universitas Airlangga Kampus B Universitas Airlangga,Jalan Airlangga 4 Surabaya, Indonesia, Nugraha Loebby Adama , Kartika Nurullaily ,   Departemen Ilmu Manajemen, Fakultas Ekonomi dan Bisnis,Universitas Airlangga Kampus B Universitas Airlangga,Jalan Airlangga 4 Surabaya, Indonesia
Published: October 2022

Penelitian ini bertujuan untuk mengetahui strategi yang efektif dan efisien untuk pengembangan bisnis Bebys Coffee. Penelitian ini menggunakan data primer dengan penyebaran kuesioner kepada 6 responden yang bergerak di bidang industri kopi, menggunakan pendekatan konsumen dimana pendekatan kualitatif deskriptif. Pengujian rumusan masalah menggunakan metode analisis SWOT (Strength, Weakness, Opportunity, Threat) dengan Neutrosophic Analytic Hierarchy Process (NAHP). Hasil penelitian menunjukkan perumusan strategi pengembangan bisnis Kopi Bebys berupa strategi keunggulan komparatif (SO) dengan perluasan merek; strategi investasi (WO) in-store dan infrastruktur pemasaran; strategi mobilisasi (ST) di ceruk pasar dengan diferensiasi produk linier dan strategi pengendalian kerusakan (WT) dengan strategi perang harga untuk meningkatkan kesadaran dan menutupi biaya operasional. Keterbatasan penelitian ini adalah hanya bersifat deskriptif dan kualitatif yang menitikberatkan pada pengembangan strategi manajemen yang komprehensif dan tidak mengembangkan strategi manajemen yang lebih detail pada hal-hal teknis. Maka, Bebys Coffee memerlukan analisis SWOT menggunakan NAHP untuk menangkap peluang dari tingginya permintaan minuman kopi dan menghadapi ancaman kompetitor yang memiliki brand kuat dan toko yang lebih nyaman
Pengaruh Transformational Leadership pada Innovative Behaviour yang Dimediasi oleh Psychological Empowerment dan Knowledge Sharing
Authors:   Fakultas Ekonomi dan Bisnis, Universitas Airlangga Kampus B Unair, Jalan Airlangga 4 Surabaya, Indonesia, Kurniawati Nufia Ayu , Agustina Tri Siwi ,   Fakultas Ekonomi dan Bisnis, Universitas Airlangga Kampus B Unair, Jalan Airlangga 4 Surabaya, Indonesia
Published: October 2022

Penelitian ini bertujuan untuk menguji pengaruh transformational leadership terhadap innovativebehaviour yang dimediasi oleh psychological empowerment dan knowledgesharing pada guru SMKS Brantas Karangkates. Studi ini menggunakan pendekatan kuantitatif dengan cara mengumpulkan data dari proses survey, wawancara, serta kuisioner offline. Teknik pengambilan sampel menggunakan sampling sensus. Namun sampel responden yang kembali sebanyak 59 responden dari total populasi sebanyak 104 guru SMKS Brantas Karangkates. Sementara untuk teknik pengujian data yang digunakan adalah Smart PLS 3.0. Tidak ada pengaruh signifikan antara transformational leadership terhadap innovativebehaviour guru SMKS Brantas Karangkates. Namun transformational leadership berpengaruh positif dan signifikan terhadap psychological empowerment dan knowledge sharing. Hasil penelitian juga menunjukkan bahwa psychological empowerment dan knowledge sharing memediasi penuh pengaruh transformational leadership terhadap innovative behaviour pada guru SMKS Brantas Karangkates Malang. Akhirnya, penelitian ini menemukan bahwa psychological empowerment dan knowledge sharing memiliki peranan yang besar dan signifikan untuk kepala sekolah SMKS Brantas Karangkates dan jajarannya dalam memaksimalkan peran transformational leadership guna mengefektifkan innovative behaviour para guru di sekolah.
Pendekatan Asset-Based Community Development dalam Mengelola Bumdesa di Desa Cibogo, Kabupaten Tangerang
Authors:   PoliteknikKeuanganNegaraSTAN,Jl.BintaroUtamaSektorV,JurangMangguTim.,Kec.Pd.Aren,KotaTangerangSelatan,Banten15222, Raharjo Taufik , Setiawan Kusmulyono Muhammad ,   Sekolah Bisnisdan Ekonomi,Universitas Prasetiya Mulya BSD City Kavling EdutownI.1,Jl.BSD RayaUtamaNo.1,BSDCity,Tangerang,Banten1533
Published: October 2022

Bumdesa menjadi motor pengembangan perekonomian desa dalam 8 tahun terakhir. Akan tetapi,pemilihan unit usaha Bumdesa sering menjadi hal yang diabaikan dan tidak disesuaikan denganpotensi yang sebenarnya dimiliki oleh desa. Akibatnya, banyak Bumdesa yang tidak mampumengoptimalkan unit usaha yang sudah dijalankan walaupun memiliki alokasi anggaran yangbesar. Melalui pendekatan ABCD, konsep pengembangan desa diarahkan untuk menguatkan potensidasar yang sudah dimiliki oleh desa baik dari sisi alam maupun sumber daya manusia. BumdesaMitraCibogoSejahterasebagaistudikasusBumdesayangmenggunakanpendekatanABCDmenunjukkanbahwahasilkinerjausahalebihstabilwalaupunbelumsesuaiharapanyangutama.Melalui penelitian kualitatif dengan wawancara mendalam kepada 12 pemangku kepentingan terkaitBumdesa MCS, diperoleh hasil analisis yang menunjukkan bahwa pendekatan ABCD ternyata mampumeminimalisasi risiko kegagalan sehingga usaha Bumdesa MCS yang dijalankan dapat menjadilebih fokus. Hasil penelitian menunjukkan bahwa penerapan konsep ABCD tidak hanya didasarkanpada pemilihan aset saja, namun perlu diperkuat dengan profesionalisme manajemen Bumdesa,komunikasiyangkonstruktifdenganpemerintahdesa,dankesediaanmanajemenBumdesauntukterbuka dengan kondisi yang ada. Hal ini ternyata menjadi determinan kuat stabilnya kinerjaBumdesaMCSyangmenggunakankonsepABCD.
Factors Influencing Buying Intention of Organic Food
Authors:   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Ramadhan Adam , Janitra Evan Saputra ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Muljono Fernando Eric ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Utamawati Intan ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Wijaya Mudita ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Istijanto Istijanto ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430
Published: October 2022

This research aims to increase a significant and critical issue about the number of people affected by cancer in the world. One solution to reducing the risk of cancer and improving a healthier lifestyle is consuming more organic foods. This study investigated five factors influencing the intention to buy organic foods, namely lifestyle adaptation, social media influence, food consumption awareness, environmental attributes, and attitudes toward organic food. Primary data collection was conducted in urban cities such as Greater Jakarta, Indonesia by using quantitative research and with a total of 300 respondents. Descriptive and regression analyses were used to analyse the collected data. The results of the research revealed that organic food’s buying intention depended on lifestyle adaptation, food consumption awareness, environmental attributes, and attitudes towards organic foods. These findings will contribute to the theory of consumer behaviour as well as practitioners in organic food areas.
Rantai Nilai dan Model Bisnis Fashion pada Brand Lokal
Authors:   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Feodora Fontanna Ofira , Handoyo Anastasia Irene ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Cendana Graciela ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Moses John Pier’s ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Suhartanto Eko ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430
Published: October 2022

In this study, we analyze the implementation of Musse Official's corporate strategy to face the intense competition in the fashion industry, as well as the obstacles encountered. Specifically, this study presents Musse Official value chain analysis, which is based on the results of depth interviews with Musse Official’s owner. Facing a competing strategy that dares to spend money on a large scale, Musse Official puts customer engagement as its competitive advantage. For example, a promotional program for loyal consumers and convenience return of goods process. In addition, accuracy in procurement of goods and agile supply chain is also part of the Official Musse strategy.
Bees in the City
Authors: Falencka-Jablonska Malgorzata
Published: October 2022

For many years, the need to increase food production, both globally and locally, has been directly related to agriculture intensification. The need to systematically increase the doses of both artificial fertilizers and chemical plant protection products increases the threat to the components of the natural environment. This condition is hazardous and has far-reaching consequences for pollinating insects, especially bees. Consequently, the number of these is decreasing, and their susceptibility to numerous diseases is increasing significantly. The research results indicate that they pollinate 80% of plants on our planet, especially such essential utility species as vegetables and fruits. To counteract and limit the harmful effects of chemical plant protection products on the life of these insects, in 2018, the European Union issued a ban on the use of the most potent pesticides, i.e., neonicotinoids, and glyphosate, the main ingredient of Roundup. One method of helping these insects are urban apiaries which can help in reducing their exposure to diseases and, consequently, their mortality. The practice of establishing beehives in the cities of Europe and other countries around the world has been observed for several decades now, and in Poland it has a tradition of several years. The number of such apiaries is increasing, as the urban landscape provides a rich and varied diet for bees.
Quality of Life from a Transhumanist Perspective
Authors: Plašienková Zlatica , Farbák Martin , Smolková Eva
Published: October 2022

The issue of quality of life has been a subject of major interest in the course of history, even though it was originally related to a specific philosophical question of a good life. Nowadays, the quality-of-life issue represents a more complex term, related to a lot of aspects that make human life good, valuable and meaningful. In this article, the authors aim to reflect on the new role of transhumanism, which is promoting a radical scientific and technological enhancement of humans. In its promising visions, the level of quality of human life should be supposedly increased to an almost ideal state for all people. Initially, the authors deal with the issue of the quality of human life concerning individual preferences and social solutions, and they proceed with their beliefs based on the assumption that the guarantor of the life of citizens is the state government. Later on, the authors of the article focus on the given issue relating to transhumanist positions. They critically analyse the transhumanist absolutization of technology as the primary tool for achieving a good human life, whilst overlooking the ethical context of the issue. The authors express their positive standpoint towards human progress and enhancement (especially in medicine), but they recognise a possible risk of dehumanisation. If the transhumanist visions are to be carried out by prioritizing the progress itself before the actual humans, there are deep ethical questions that should be answered.
Adenosine Receptor Antagonists: Structures and Potential Therapeutic Applications
Authors: Muller C. E. , Stein B.
Published: October 2022

Adenosine Receptors (AR) are widely distributed in the human body. Four distinct AR subtypes, designated A1, A2a, A2b, and A3, have been identified on a pharmacological basis (affinity profile of agonists and antagonists; second messenger systems) as well as on a molecular level (cloning from various species, including humans). The current article focusses on recent advances in the development of subtype-selective AR antagonists, structure-activity relationships (SAR) of xanthine and non-xanthine A!-, A2a-, A2b- and A3-AR antagonists, and their in-vivo actions. Special attention is given to the cardiovascular effects mediated by AR agonists and antagonists. Potential therapeutic applications for AR ligands, particularly antagonists, in the cardiovascular area and other fields (e.g. CNS, kidney) are discussed.
Structural Aspects of Factor Xa Inhibition
Authors: Stubbs II Milton T.
Published: October 2022

Factor Xa is responsible for both extrinsic and intrinsic generation of active thrombin. The recent structure determination of human factor Xa provides a basis for structure based drug design. Until very recently, however, it .has not been possible to analyse factor Xa - ligand interactions directly. A semi-conservative modelling approach, in which the interaction of factor Xa inhibitors with related serine proteinases is investigated, has yielded valuable information on the structural determinants for factor Xa inhibition. The interactions of factor Xa with DX9065a, tissue factor pathway inhibitor (TFPI), variants of basic pancre tic trypsin inhibitor (BPTI) and tick anticoagulant peptide (TAP) are discussed.
Biosynthesis of Terpenoids By Plants
Authors: Niitsu Akemi L. , Bornhofen Elesandro , Bergonci Tábata
Published: October 2022

Terpenoids are a class of chemicals with over 50,000 individual compounds,
highly diverse in chemical structure, founded in all kingdoms of life, and are the largest
group of secondary plant metabolites. Also known as isoprenoids, their structure began
to be elucidated between the 1940s and 1960s, when their basic isoprenoid building
blocks were characterized. They play several basic and specialized physiological
functions in plants through direct and indirect interactions. Terpenoids are essential to
metabolic processes, including post-translational protein modifications, photosynthesis,
and intracellular signaling. All terpenoids are built through C5
units condensed to
prenyl diphosphate intermediates. The fusion of these C5
units generates short C15-C25,
medium C30-C35, and long-chain C40-Cn terpenoids. Along with the extension of the
chain, the introduction of functional groups, such as ketones, alcohol, esters and,
ethers, forms the precursors to hormones, sterols, carotenoids, and ubiquinone
synthesis. The biosynthesis of terpenoids is regulated by spatial, temporal,
transcriptional, and post-transcriptional factors. This chapter gives an overview of
terpenoid biosynthesis, focusing on both cytoplasmic and plastid pathways, and
highlights recent advances in the regulation of its metabolic pathways.
Volatile Terpenoids of Annonaceae: Occurrence and Reported Activities
Authors: Cascaes Márcia M. , S. P. Guilhon Giselle M. , Nascimento Lidiane D. , B. de Moraes Angelo A. , G. Silva Sebastião , Neves Cruz Jorddy , Ferreira Oberdan O. , Oliveira Mozaniel S. , Andrade Eloisa H. A.
Published: October 2022

Annonaceae includes 2,106 species. Some species of this family have an
economic interest in the international fresh fruit market and are often used as raw
materials for cosmetics, perfumes and folk medicine. The most cited species are mainly
those belonging to the genera Annona, Guatteria and Xylopia. Chemical investigations
indicate that the characteristic constituents of the Annonaceae are terpenoids, including
mono and sesquiterpenoids, such as α-pinene, β-pinene, limonene, (E)-caryophyllene,
bicyclogermacrene, caryophyllene oxide, germacrene D, spathulenol and β-elemene.
Antimicrobial, antioxidant, larvicidal, antiproliferative, trypanocidal, antimalarial and
anti-inflammatory effects have been described in these terpenes. This work is an
overview of the chemical properties and biological effects of the volatile terpenoids
from Annonaceae species.
Applications of Natural Terpenoids as Food Additives
Authors: Figueiredo Bezerra Fernanda Wariss , Melo Aires Giselle Cristine , Cantão Freitas Lucas , Rodriguez Salazar Marielba de Los Angeles , Holanda Pinto Rafael Henrique , da Cruz Jorddy Neves , de Carvalho Junior Raul Nunes
Published: October 2022

Food additives are widely used in the food industry in order to ensure the quality of products during processing, storage, packaging and subsequent reaching the consumer's table. The growing concern and doubt of the consumer market regarding artificial additives and their possible harmful effects on public health and safety have caused the demand for the use of natural additives to increase. Consequently, these natural additives have been increasingly sought by the food industry and consumers due to health, safety and sustainability issues. In this framework, terpenoids have great potential to be used with this function because they are a very extensive class of compounds, with wide chemical diversity and several proven applications in foods, mainly as anti-oxidants, anti-microbials, dyes, flavors, sweeteners and nutraceuticals. Therefore, this paper aims to make a literature search on the use of terpenoids as food additives, highlighting the main compounds used and the benefits associated with their use, ranging from the raw material to its extraction and subsequent application in food products.
Terpenoids in Propolis and Geopropolis and Applications
Authors: Neves Cruz Jorddy , de Oliveira Mozaniel Santana , de Meneses Costa Ferreira Lindalva Maria , Santiago Pereira Daniel , de Holanda Neto João Paulo , de Medeiros Aline Carla , Borges Maracajá Patrício , da Silva Souza Filho Antônio Pedro
Published: October 2022

Propolis is a resin, which comes from from bee colonies and is considered a
natural antibiotic, without serious side effects, compared to synthetic treatments, and
has several pharmacological properties. Geopropolis is a mixture of clay and propolis
produced by species of stingless bees of the genus Melipona, hence the name
geopropolis. It is formed in the same way as propolis produced by other bee species. In
this review, we aim to address general aspects related to terpenoids present in propolis
and geopropolis. Here, we report the main terpenoids, their chemical structure, and
pharmacological and food industry applications
An Intelligent Surveillance System for Human Behavior Recognition: An Exhaustive Survey
Authors: Jayaswal Ruchi , Dixit Manish
Published: October 2022

Understanding the behavior of humans is a very important concern for socialcommunication. Especially in real-time, predicting human activity and behavior hasbecome the most vigorous research area in digital image processing and computervision. To enhance the security in public and private domains in the field of humancomputerinteraction and intelligent video surveillance, human behavior analysis is animportant challenge in various applications. There are many basic approaches toanalyze human activity, but recently, deep learning approaches have been shown thatyield very interesting results in different domains. Human actions and behavior can beobserved in the open as well as in sensitive areas, such as airports, banks, bus and trainstation, colleges, parking areas, etc., and prevent terrorism, theft, accidents, fighting, aswell as other abnormal and suspicious activities through visual surveillance. Thischapter thus seeks to reflect on methods of human activity recognition. This chapterpresents a brief overview on human behavior recognition along with its challenges orissues and applications. Also, we have discussed the framework of recognition ofsuspicious human activity and various datasets used to train the system. The objectiveof this chapter is to provide general information about human behavior analysis andrecent methods used in this field.
An Overview of Energy Efficient and Data Accuracy Target Tracking Methods in WSN
Authors: Saraswat Urvashi , Yadav Anita
Published: October 2022

Target tracking plays an important role in an application of WSN (WirelessSensor Networks) with its growing popularity for various industrial as well commercialpurposes. Many researches have been done for laying the framework of a targettracking algorithm to achieve accuracy while tracking down the target. Although thebasic structure of a target tracking algorithm focuses on accuracy but the cooperation ofboth data accuracy and efficient energy utilization is quite distinct goal in the designingof target tracking algorithms. Through this survey, we present some recent target-basedtracking algorithms that focus on dual goal, i.e., efficient power consumption alongwith the data accuracy. In this paper, we present a comparative structure that showcasesthat all surveyed algorithms are still on the verge of improved tracking accuracy withenergy efficiency and there is still a need of optimization in terms of energy-efficientusage. The primary focus of the paper is to survey the level of energy efficiency indifferent categories of target tracking algorithms laid down in Wireless SensorNetworks.
A Survey of Current Mobile Learning Technology in India
Authors: Gupta Pooja , Kumar Vimal
Published: October 2022

Mobile learning technology is playing a vital role in today's education due toCOVID-19. The ongoing pandemic has increased its demand and usage everywhere inthe world. It is a technology that enables students to learn, interact, collaborate, andaccess education from any place and at any time by using internet-enabled mobiledevices. These mobile devices include laptops, tablets, and mobile phones for distancelearning. In the current scenario, this distance learning has proved as a boon, especiallyin the education and corporate sector widely. However, M-learning can also be appliedin other fields, such as financial sectors, including banking, and non-financial sectors,including healthcare, industrial sector, etc. Mobile learning acceptance is a requirementthat is still in progress. It has been adopted more in urban schools and higher educationinstitutions in comparison to rural and secondary schools. Our study explores theevolution of M-learning, benefits, challenges, platforms, and various factors that affectmobile learning adoption. We have also discussed the existing models and frameworksfor learning in higher education, university, etc. Hence, in this study, we have focusedboth on the positive and negative outcomes of all the previous studies to eliminate theissues and increase mobile learning adoption in the future. The main highlight of thispaper is that we have presented various online platforms available for individuals,organizations, and enterprises for learning. These tools are as important as consideringvarious other factors that have been discussed in previous findings. Moreover, acomparison table of various factors and conclusions of different researchers is shown.Furthermore, it has been concluded that the adoption of mobile learning technologymust be increased in developing countries.
Coal Workers Pneumoconiosis
Authors: Zulfikar Rafia , Parker John E.
Published: October 2022

Coal Worker’s Pneumoconiosis (CWP) was thought to be an archaic
disease, but after an initial decline because of the Coal Mine Health and Safety Act in
1969, there has been a resurgence of this disease in the 21st century. For centuries,
miners have been exposed to varied types and degrees of coal mine dust. Lung diseases
in coal miners are caused by the inhalation, retention, and tissue reaction to the mixed
constituents of this dust, which include carbon, silica, and silicates. Respirable dust
particles of less than 5 microns are deposited in the proximal and distal airways and the
smaller particles are deposited in the alveoli. The tissue reaction to these particles
results in a variety of pathologic lesions, including coal macules, silicotic nodules,
mixed dust pneumoconiosis, interstitial fibrosis, progressive massive fibrosis,
bronchitis, and emphysema. These disorders are recognized primarily through
occupational exposure history and characteristic radiographic imaging. With a latency
of approximately 20 years, cumulative lifetime exposures appear to be most predictive
of the disease severity. Prevention of these diseases should be the primary focus of the
industry, the workforce, and the public health agencies. In the US, federal programs of
screening and surveillance are in place and active. The treatment of these disorders as
with other chronic respiratory conditions, is focused on vaccinations against respiratory
infection, bronchodilator therapy when indicated, supplemental oxygen therapy when
required, pulmonary rehabilitation programs, smoking cessation, vigilant observation
for chronic respiratory infections, and if necessary, lung transplantation should be
considered as the last resort.
Occupational Cancer
Authors: Bang Ki Moon
Published: October 2022

This chapter provides an up-to-date review of the occurrence and causes of
occupational cancer based on epidemiologic studies and discusses the epidemiology of
occupational cancer, the characteristics, research priorities, prevention, and
surveillance. Epidemiologic methods have been very successful in documenting cancer
risks associated with agents. Epidemiologic data is useful when an exposure-response
relationship can be demonstrated. Examples of agents for which epidemiologic studies
provide evidence of an exposure-response relationship include benzene and
myelogenous leukemia. Vinyl chloride causes liver cancer which is an example of
associations between single agents and rare histologic types of cancer. It is more
difficult to conduct epidemiologic studies to identify cancer risks associated with
complex mixtures. Studies of diesel exhaust, lung cancer, and metal machining oils are
cited as having employed advanced industrial hygiene and epidemiologic methods for
studies of complex mixtures. At present, less than 20 known occupational carcinogenic
agents have been evaluated based on studies in humans and animals by the
International Agent for Research on Cancer. Furthermore, exciting developments in
epidemiologic and animal studies will contribute to identifying additional carcinogenic
agents in the workplace. New biologic markers of exposure and cancer-related
outcomes must be identified and integrated into epidemiologic studies. Because
epidemiologic data regarding the carcinogenicity of many exposures are not available,
research methods to evaluate and improve the predictive value of animal and in vitro
systems must be developed. A complete understanding of occupational cancer trends
will be required further to research occupational cancer risks and means of prevention.
Construction: Accessing and Working on Elevated Work Surfaces Safely
Authors: McKenzie, Jr. E.A. , Hause Mathew G. , Bobick Thomas G.
Published: October 2022

This chapter provides general information and educational resources that can
explain methods to safely access elevated worksites in the construction industry and
develop teaching and training tools from the provided content. Fatality data are
presented to emphasize the dangerous nature of construction work at elevations. These
data verify that falls from elevations are still the primary cause of fatal injuries in the
construction industry. The NIOSH Fatality Assessment and Control Evaluation
(FACE) program is highlighted throughout the chapter. The NIOSH FACE database of
fatality reports identifies risk factors and recommendations for mitigating future fatal
injuries. Additionally, NIOSH research activities are discussed that relate to fall
prevention and protection. The activities discussed are a sample of popular fall
protection techniques available to construction workers. They emphasize creating a
safe working environment using ladders, scaffolds, and lifts through proper training
and awareness. Proper planning, training, and practice can reduce the potential of fatal
fall-related incidents from occurring.
Work-related Musculoskeletal Disorders
Authors: Lu Ming-Lun , Lowe Brian D. , Howard Ninica L. , Meyers Alysha R. , Fox Robert R. , Dong Ren G. , Baker Brent A.
Published: October 2022

In most industrialized countries, work-related musculoskeletal disorders
(WMSDs) are a major occupational health problem resulting in productivity loss,
employee absenteeism, and high workers’ compensation and healthcare costs.
Understanding the etiology and control of WMSDs and associated risk factors is
imperative for reducing the burden of this problem. This chapter is organized by five
topics on WMSDs: (1) the problem and surveillance of WMSDs; (2) the etiology of
WMSDs and their risk factors; (3) risk assessment methods for job-related physical risk
factors; (4) risk intervention effectiveness; and (5) ergonomic guidelines and standards
for the prevention of WMSDs. The authors focus on the breadth of the scientific
knowledge and literature pertaining to WMSDs for occupational safety and health
professionals interested in learning about the field of ergonomics. This chapter also
provides anticipated future challenges in the areas of surveillance, risk interactions, risk
assessments, and intervention evaluations. The research agenda for WMSDs published
by the National Occupational Research Agenda (NORA) Musculoskeletal Health
Cross-Sector (MUS) Council in 2018 is recommended as supplementary reading for the
future direction of WMSD research.
The Science of Catalysts in Algae Oil Production
Authors: Koyunoğlu Cemil , Karaca Hüseyin
Published: October 2022

CO2, which is a gas produced as a result of combustion, has an importantshare in greenhouse gases such as SOx, CO, and NOx and causes global warming. Asbiodiesel produced from algae converts CO2 within the biological carbon cycle, itaccelerates the carbon cycle, as a result of which the greenhouse gas effect decreases.C16-C18 methyl esters in biodiesel whose degradability feature resembles dextrose(sugar) do not show any negative microbiological affect up to 10000 mg/L, theydecompose rapidly in nature. 40% of diesel in water and 95% of biodiesel in 28 dayscan be degraded. In the production of biodiesel, catalysts that break the triglyceridebonds allow the esters to become free.
Exogeneous-triggered Delivery in Localized Controlled Drug Delivery Systems (LCDDSs)
Authors: Naghib Seyed Morteza , Hoseinpour Samin , Zarshad Shadi
Published: October 2022

Stimuli-sensitive materials and micro/nanostructures can be manipulated to
release their therapeutic drugs in the target site. The release is based on a particular
extracellular/cellular stimuli, triggered via physical, biochemical, and chemical
changes. The trigger may change the carrier structure/chemistry to release the
therapeutic drug at a specific site. When a therapeutic drug is encapsulated with a
stimuli-triggered material/polymer, the release may start with changes in structures like
charge switching, surface layers de-shedding and degradation of materials.
Furthermore, the disruption of the bonds may result in the release of therapeutic agents
that are covalently immobilized in the functional groups of materials. Exogenous
stimuli are the activation of reactions/phenomena from outside the body, such as
ultrasound, temperature and light. Herein, we will describe thermosensitive, light.sensitive, and ultrasound-sensitive controlled drug release of LCDDS, as the mentioned
exogenous stimuli have been extensively used in LCDD applications.
Additive Manufacturing in Developing Localized Controlled Drug Delivery Systems (LCDDSs)
Authors: Naghib Seyed Morteza , Hoseinpour Samin , Zarshad Shadi
Published: October 2022

Patients may show various defects to medications depending on race,
gender, fitness, age, pharmacokinetic and health conditions. To address this challenge,
there is a need to establish personalized, on-demand, programable and smart carriers
that can control drug release with new and robust techniques. Additive manufacturing
(AM) is the key sustenance of digital technology that has been developing and growing
recently. AM offers several opportunities in localized controlled drug delivery systems
(LCDDS), including materials recycling as well as on-site manufacturing, design
freedom and full customization. Moreover, the industrial, biomedical and academic
requests for AM for LCDDS have been continually rising, demonstrating significant
marks for an extensive range of products. This chapter outlines AM approaches and
their functions for LCDDS and describes AM technologies, such as recent advances in
controlled drug release, as well as their processed materials and working principles.
Furthermore, the benefits of 3D printing in the progressions of the LCDDS, the
advantages of 4D printing, the impression of designing and material selection in these
techniques are discussed. Finally, the potentials of AM approaches and their LCDD
applications that designate a promising healthcare future are described.
Primary Microcephaly and Schizophrenia: Genetics, Diagnostics and Current Therapeutics
Authors: Anjum Iram , Saeed Aysha , Aslam Komal , Murtaza Bibi Nazia , Mahmood Baig Shahid
Published: October 2022

Intellectual disabilities (ID) are among the most common genetic disabilities
worldwide. Over the last two decades, ID has especially drawn special scientific
interest being the key to understanding normal brain development, growth, and
functioning. Here, we discuss two intellectual disabilities to better understand the
emerging trends in disease diagnosis as well as the therapies available for their
management. Primary microcephaly (MCPH) is a monogenic genetic disorder with
twenty-eight loci (MCPH1-MCPH28) mapped so far with all the causative genes being
elucidated as well. The role of these genes in disease prognosis along with their
association with various MCPH-linked phenotypes plays an important role in the
molecular diagnosis of the disease. As there is no cure/treatment yet available to
enlarge a congenitally small brain, management modalities in use include physical,
speech and occupational therapies as well as psychological and genetic counselling to
not only reduce the incidence of the disorder but also to help families cope better. The
second intellectual disability being discussed here is schizophrenia which is a
multifactorial disorder owing to its complex and extremely heterogeneous etiology.
Although various environmental factors play an important role, the genetic factors have
been identified to play the most pivotal role in disease presentation as to date, 19 loci
(SCZD1-SCZD19) have been linked to schizophrenia. However, underlying genes for
only six of these loci have been mapped along with 10 other genes that are either linked
to schizophrenia or show susceptibility to it. Diagnosis of schizophrenia needs careful
consideration and various tests and tools currently employed for complete diagnosis
have been discussed here. The management options for schizophrenia include
pharmacological, non-pharmacological and intracranial therapies. These disorders shed
light on the important role omics technologies have played not only in better
understanding of the disease prognosis but also assisting in disease diagnosis and
treatment modalities too.