bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation on Medium-Term Performances of Porous Asphalt and Their Impacts on Tire/Pavement Noise
Authors: Wu Hao , Wang Ge , Li Ming Liang , Zhao Yue , Li Jun , Han Ding Ding , Li Peng Fei
Published: December 2023

As the lifespan of porous asphalt pavement extends, it invariably experiences performance degradation and an increase in tire/pavement noise compared with the original surface when it is newly built. To understand the medium-term performance of porous asphalt pavement during service and reveal the influence of different pavement performance indicators on tire/pavement noise generation, a seven-year continuous observation and data analysis study was conducted. Porous asphalt with different designed material parameters was taken into account, including thin-layer porous asphalt overlay with a maximum nominal aggregate size of 10mm (PUC-10), porous asphalt with a maximum nominal aggregate size of 13mm (PAC-13), and a two-layer porous asphalt incorporating both PUC-10 and PAC-13 (PUC-10+PAC-13). Using automated pavement technology testing equipment, key performance indexes, including damage rate (DR), rut depth (RD), international roughness index (IRI), and sideway force coefficient (SFC), were measured and calculated. The on-board sound intensity (OBSI) method was used to test noise levels in three types of porous asphalt pavement structures and on a dense graded easy compact asphalt concrete (ECA) for comparison. The progressions of the medium-term performances were analyzed according to the measured results. The correlations between tire/pavement noise levels and testing speed, testing lane, pavement structure, and road condition indicators were investigated by regression. The research results revealed that the DR and SFC of the three types of porous asphalt pavement displayed more significant attenuation in the service period, while the IRI and RD showed small changes. Among them, the SFC demonstrated significant attenuation over the first 4 years, decreasing between 13.8% and 17.0%. From the 3-7 years of operation, the transverse crack disease in porous asphalt pavement progressed rapidly. The three porous asphalt pavement structures tested exhibited commendable noise reduction capabilities. Compared to ECA, the OBSI noise levels of these structures were lower by 2.09 dB, 1.53 dB, and 2.88 dB, respectively. Compared to other pavement condition indicators, RD had a more significant impact on the OBSI value of the PUC-10 porous asphalt pavement. For the PUC-10+PAC-13 porous asphalt pavement, there was a significant linear relationship between the OBSI value and SFC, mainly due to polishing of the coarse aggregate surface. It leads to a decrease of the micro-texture, which lies in increasing tire/pavement noise at high-frequency ranges and decreasing SFC. This study will have guiding significance for the research of the attenuated law and durability improvement of porous asphalt tire/pavement noise.
Multilayer Perceptron-based Error Compensation for Automatic On-the-Fly Camera Orientation Estimation using a Single Vanishing Point from Road Lane
Authors: Li Xingyou , Kim Hyoungrae , Kakani Vijay , Kim Hakil
Published: December 2023

This study introduces a multilayer perceptron (MLP) error compensation method for real-time camera orientation estimation, leveraging a single vanishing point and road lane lines within a steady-state framework. The research emphasizes cameras with a roll angle of 0°, predominant in autonomous vehicle contexts. The methodology estimates pitch and yaw angles using a single image and integrates two Kalman filter models with inputs from image points (u, v) and derived angles (pitch, yaw). Performance metrics, including AE, MINE, MAXE, SSE, and STDEV, were utilized, testing the system in both simulator and real-vehicle environments. The outcomes indicate that our method notably enhances the accuracy of camera orientation estimations, consistently outpacing competing techniques across varied scenarios. This method’s potency is evident in its adaptability and precision, holding promise for advanced vehicle systems and real-world applications.
Chemical Vapor Deposited 2D MoN Nanosheets as Stable and Uniform Surface Enhanced Raman Scattering Substrate with Thickness Dependent Sensitivity
Authors: Wu Hongrong , Tang Maolin , Tong Pinsen , Hang Yang , Zhao Junhua
Published: December 2023

Two-dimensional (2D) materials show advantages as surface enhanced Raman scattering (SERS) substrate over traditional noble metals, such as chemically inert flat surface and uniform SERS signals. However, due to the low density of free electrons of 2D materials, the enhancement mechanism is mainly restricted to chemical enhancement instead of electromagnetic enhancement, resulting a relatively low enhancement factor. In this work, we reported a sensitive 2D SERS substrate based on chemical vapor deposited MoN nanosheets with electromagnetic enhanced mechanism. The maximum enhancement factor can be 3×105 with a limit of detected concentration of 4×10-8 M, which is comparable to those noble metal SERS substrates without hot spots. The MoN nanosheets show strong surface plasmon resonance in the visible range as evidenced by the UV-vis absorption spectroscopy and first principle calculation. The MoN nanosheets SERS substrates exhibit excellent Raman signal uniformity within the nanosheets. Meanwhile, Distinct thickness dependent sensitivity was observed in the MoN nanosheets, higher sensitivity can be achieved by decreasing the thickness of the nanosheets. Furthermore, the MoN nanosheets SERS substrate also show high thermal stability, which can be annealed in air for more than 300℃ and maintain its SERS activity. The high stability of MoN nanosheets allows it to be reused for 20 cycles without obvious signal decay. The high sensitivity, stability, reusability and Raman signal uniformity, makes MoN nanosheets an ideal 2D SERS substrate for practical applications.
Typology of Milkfish (Chanos chanos) Farms: Their Operations, Socio-Economic Viability, and Challenges
Authors: Macusi Edison D. , Macusi Erna S. , Bongas Henzel P. , Cayacay Melanie A.
Published: December 2023

Milkfish (Chanos chanos) locally called Bangus in the Philippines, is a popular food fish in terms of production and consumption in the Philippines, Indonesia and Taiwan. This study characterized a typical grow-out milkfish farm in the Davao region in terms of socioeconomic profile, farming practices, and simple costs and returns. Three sites were chosen to conduct this study, mainly in Mati, Pantukan and Panabo in Davao region where N=43 farm workers provided information on their daily farming practices. Farms are commonly stocked with 16,000 fingerlings, harvesting occurs after every 6 months with six feeding times in a day. Moreover, workers were paid an average of Php 10,000 per month while the company had a gross income of Php 930,000 per cropping cycle. The feed cost shares 76% of the overall operational cost with a 27% return on investment for the first year of operation. Climate change impacts (e.g. higher sea surface temperature, unpredictable weather and flooding) and deteriorating water quality conditions were seen as bigger threats. Other results showed a positive relationship between stocking density and volume harvested (df=1, MS=0.0907, F=40.13, P=0.000) and income (df=1, MS=0.048, F=21.22, P=0.000). The study also showed the need for cheaper feed substitute and better benefits to farm workers.
Esters in Industry: An Overview of the Reactors Used in Their Biocatalytic Synthesis
Authors: Ortega-Requena Salvadora , Montiel Claudia , Máximo Fuensanta , Gómez María , Murcia María Dolores , Bastida Josefa
Published: December 2023

Esters are versatile compounds with a wide range of applications in various industries due to their unique properties and pleasant aromas. Conventionally, the manufacture of these compounds has relied on the chemical route. Nevertheless, this technique employs high temperatures and inorganic catalysts, resulting in undesired additional steps to purify the final product by removing solvent residues, which decreases environmental sustainability and energy efficiency. In accordance with the principles of “Green Chemistry” and the search for more environmentally friendly methods, a new alternative, the enzymatic route, has been introduced. This technique uses low temperatures and does not require the use of solvents, resulting in more environmentally friendly final products. In spite of the large number of studies published on the biocatalytic synthesis of esters, little attention has been paid to the reactors used for it. Therefore, it is convenient to gather the scattered information regarding the type of reactor employed in these synthesis reactions, considering the industrial field in which the process is carried out. The comparison between the performance of the different reactor configurations will allow us to draw the appropriate conclusions regarding their suitability for each specific industrial application.
Automatic Fire Suppression of Home Automation System Using Graphic System Design
Authors: C Marimuthu , V Janani , R Kaviyanjali , N Priyanka , M Suba
Published: December 2023

This project involves the development of Fire Suppression System (FSS) leveraging of Home automation system using Graphical System design (LabVIEW) software and Arduino microcontroller for real-time monitoring and control. The system integrates an Infrared (IR) flame sensor, an MQ2 gas sensor to detect and suppress fire hazards efficiently. The LabVIEW interface facilitates real-time monitoring of sensor data, allowing users to visualize and analyze the environmental conditions. Through this system, fires are automatically subdued, enhancing safety without requiring human intervention. This advances fire safety by swiftly containing threats and minimizing potential damage.
Estimation of Validity of A-Mode Ultrasound for Measurements of Subcutaneous Fat Thickness, Muscle Thickness, and MUSCLE quality
Authors: Lee Ji-Won , Hong Seung-Ug , Lee Ju-Hee , Park Sung-Yun
Published: December 2023

We aimed to determine whether A-mode ultrasound (US) can provide accurate and reliable measurements comparable to those obtained through B-mode US, under diverse conditions. Thirty healthy participants (15 female, 15 male) underwent measurements of subcutaneous fat thickness (SFT), muscle thickness (MT), and muscle quality (MQ) in the trapezius and biceps brachii muscle with both US modes after and before exercises designed to stimulate the respec-tive muscles. In three key indices, the results demonstrated high validity of A-mode, with min-imal mean differences between the two devices less than 0.91mm and intraclass correlation coef-ficients exceeding 0.95 at all measures. Also, Correlation coefficients between error scores and average scores for the trapezius and biceps brachii muscles suggested no evidence of systematic error. The trapezius MT and MQ significantly increased, and biceps brachii MT significantly in-creased after exercise (p<0.05). Notably, both A-mode and B-mode exhibited the same tendency in these post-exercise changes in muscle. This study suggests that low-cost and low-resolution A-mode US provides measurements of SFT, MT, and MQ similar to more expensive, high-resolution B-mode imaging. A-mode US can serve as an affordable and portable alternative for muscle assessment.
Numerical Study of Hydraulic Percolation in Porous Media Using Two Hydraulic Structures
Authors: Faria Albert Willian , Venâncio Stênio de Sousa , Siqueira Adriano Francisco , Romão Estaner Claro
Published: December 2023

This article investigates hydraulic percolation in saturated porous media, focusing on containment systems using sheet pile walls and gravity concrete dams. The Laplace equation, which governs hydraulic flow in porous media, is solved using the Finite Element Method through the ANSYS software. The modeling of the porous media employs a planar quadratic element called Plane 55, originally used for thermal problems, composed of four nodes and one hydraulic degree of freedom per node. The numerical results of the water pressure acting on the hydraulic structure, flow rate, and hydraulic gradient at the outlet of the porous media are compared with results obtained in the technical-scientific literature using flow nets. Two different methodologies are used to obtain the rate of seepage: by using the average hydraulic velocity or by calculating the integral of the hydraulic gradient perpendicular to the flow area. Both methodologies are compared and validated in the numerical simulations. This work also demonstrates the importance of mesh refinement for obtaining the flow rate in the studied hydraulic systems.
Sulfuric Acid Digestion of Anatase Concentrate
Authors: Silva Carolina Nogueira , Tavares Nazareth Liliani Pacheco , Freitas Monica Elizetti , Ladeira Ana Claudia Queiroz
Published: December 2023

Abstract

The processing of anatase ores by sulfuric acid digestion is well known for its low titanium dissolution yields, which makes the process economically and technically unfeasible. Generally, to enhance the dissolution of titanium from anatase, thermal processes along with acid and/or alkaline leaching are necessary. Few existing works report yields of direct digestion of anatase with sulfuric acid <48%. This study investigated the sulfuric digestion of anatase and yields around 80% were obtained at relatively mild conditions such as temperature at 220°C, sulfuric acid/concentrate ratio of 1:2 and 3 hours of reaction. A comprehensive characterization of anatase ore was also presented.
Evolution and Structure of a Mesoscale Anticyclonic Eddy in the Northwestern Japan Sea and Its Exchange with Surrounding Waters: In Situ Observations and Lagrangian Analysis
Authors: Budyansky Maxim , Ladychenko Svetlana , Lobanov Vyacheslav , Prants Sergey , Udalov Aleksandr Alekseevich
Published: December 2023

We have found a region in the northwestern Japan Sea near the Subpolar Front where mesoscale eddies regularly form and circulate. The anticyclonic eddy with a strong dynamic feature, vertically extended to the bottom (~3500 m), multilayer core structure and extreme values of temperature and salinity was sampled there in the cruise in May 2004. The altimetry-based eddy tracking showed that it had a life span of nine months with the size reaching 120 km. CTD observational data were used to explore the eddy’s features and vertical structure. The eddy had a multilayer core with different thermohaline characteristics which could be originated by eddy interaction with the surrounding waters during its life. The evolution of the eddy has been studied and analyzed with the help of altimetry-based Lagrangian indicators of water motion. Performing the particle-tracking numerical experiments, we computed the Lagrangian maps that contain information on the origin of water inside the eddy core and its ‘age’ on every day of the eddy’s life. Inspecting daily-computed Lagrangian maps, we documented the essential events in the evolution of the eddy including its formation, splitting, merger, entrainment and detrainment of water, erosion and eventual decay. All these observations have been verified with the infrared satellite images. The new Lagrangian technique has been applied to calculate day by day the content of water of various origin (coastal, subtropical and subarctic) entrained into the eddy core. It has been found that the surface core has been filled mainly with subtropical water originated in the southern flank of the Subpolar Front. The episodes with cardinal changes of ratio of different water types have been recorded and verified with the infrared satellite images and maps of the origin of water inside the eddy core.
Therapeutic Strategies in Children with Epilepsy-from the Point of View of QOL-Related Factors-
Authors: Kanemura Hideaki
Published: December 2023

Children with epilepsy are affected by several factors, including clinical and social variables, which can lead to reductions in quality of life (QOL). Among these variables, factors relating to seizure severity such as frequent seizures and status epilepticus (SE) have been identified as important predictors of QOL. In addition, frequency of interictal epileptiform discharges (IEDs) on the electroencephalogram (EEG) may also lead to cognitive declines and behavioral disturbances. Moreover, frequent seizures and/or IEDs may play a role in emotional mediators such as stigma and fatigue in childhood epilepsy. Seizure severity and/or IEDs are thus important QOL-related factors in childhood epilepsy. Frontal lobe dysfunctions such as cognitive decline and behavioral disturbances can result in reduced QOL for both the child and their family. Frontal and prefrontal lobe growth disturbances can be present during active-phase epilepsy in some children with neuropsychological impairments. Recovery from prefrontal lobe growth disturbance may depend on the active seizure period. Disturbance of prefrontal lobe growth can recover more rapidly in children with a shorter active seizure period. In contrast, recovery may be delayed in children with a longer active seizure period. Accordingly, severe seizures can lead to neuropsychological impairments in association with prefrontal lobe growth disturbance in children with epilepsy. Moreover, frequent seizures can lead to having seizure-associated headache, perception of self-stigma and parental stigma, and fatigue. In addition, IEDs on EEG, representing persistent pathological neuronal discharges, may be associated with several pathological aspects. Frontal IEDs can be a risk factor for recurrent seizures, cognitive decline, and behavioral disturbances and may also play a role as an emotional mediator similar to stigma. In addition, behavioral disturbances may result in the presence of secondary bilateral synchrony (SBS) on EEG. Behavioral disturbances can be improved in association with reduction of IEDs in children with frontal IED and SBS. Seizure severity and IEDs on EEG may thus be associated with neuropsychological impairments, leading to QOL reduction. Therapeutic management may be desirable to remit seizures and EEG abnormalities such as frontal IED and SBS as soon as possible to improve QOL in children with epilepsy.
Cultivation of Vitamin C-Rich Vegetables for Space Radiation Mitigation
Authors: Mortazavi Alireza , Yarbaksh Helia , Zarandi B.F. Bahaaddini Baigy , Yarbakhsh Reza , Ghadimi-Moghaddam Fatemeh , Mortazavi SMJ , Haghani Masoud , Firoozi Donya , Sihver Lembit
Published: December 2023

Space exploration introduces astronauts to many challenges such as space radiation and microgravity. Researchers have investigated vitamin C as a potential radiation mitigator and antioxidants for sustaining astronaut health. Building on our own studies, which indicate vitamin C's life-saving radioprotective effects and its potential as a radiation mitigator, our research highlights its promise, even when administered 24 h post-exposure. This is particularly relevant in scenarios where astronauts may be exposed to sudden large solar particle events, potentially resulting in lethal doses of space radiation. The success of vegetable cultivation on the International Space Station using NASA's Veggie system offers fresh, vitamin C-rich food. While approved supplements address somatic function, further research is needed to optimize vitamin C's efficacy in humans and develop antioxidant cocktails for space missions. The variable vitamin C content in vegetables underscores the necessity for utilization of artificial intelligence (AI) to assist astronauts in selecting and cultivating vitamin C-rich vegetables that are best suited to combat high levels of space radiation and microgravity. Particularly, AI algorithms can be utilized in analyzing various factors such as nutritional content, growth patterns, and cultivation methods. In conclusion, vitamin C shows significant potential for mitigating space radiation, and ongoing research aims to enhance astronaut health through optimal dietary strategies.
An Improved Ambiguity-free Unfolded Co-prime Linear Array Design for DOA Estimation
Authors: Gong Pan , Zhang Xiaofei
Published: December 2023

This paper considers the direction of arrival (DOA) estimation problem of phase ambiguity for unfolded coprime linear array (UCLA). The existing most common stacking subarray-based method can tackle the phase ambiguity problem. However, the method is not always true. For a given DOA, it has its corresponding steering vector, but if there are two DOAs which have the same steering vectors with the given DOA for different subarrays, the phase ambiguity problem still arises. A modified method, which defines a decision variable and uses the classic beamforming technique to estimate the DOAs is proposed. However, this method needs additional algorithm to distinguish the true DOAs besides multiple signal classification (MUSIC) spectrum. And sometimes this method is not reliable if the decision variable is not chosen appropriately. Therefore, based on the UCLA, we reconstruct the array to design an improved UCLA called IUCLA. With moving the reference element, the linear relationship among the directional vectors can be broken. In this way, we can directly utilize the MUSIC algorithm to estimate with no additional algorithm. The proposed method can solve the phase ambiguity problem and it does not demand other technique to decrease the complexity. Moreover, the Cramer-Rao Bound (CRB), as the lower bound of the unbiased estimation, is provided and numerical simulations are given to demonstrate the effectiveness and superiority of the proposed method.
The VIS-Spectrometric Data of Scots Pine Individual Seed Reveal Forecasting Potential for Container-Grown Germination and Seedling’s Dickson Quality Index
Authors: Novikova Tatyana P. , Petrishchev Evgeniy P. , Novikov Arthur I.
Published: December 2023

To follow the growth and development of each tree (N = 1200) Pinus sylvestris L., var. Negorelskaya starting from the seed and continuing at the juvenile (or even generative) stage is the goal of an ambitious project to create a plant passport if possible. Five datasets of replenished empirical (tab-ular and file) and systematic data reflect the early results of a unique ongoing experiment conducted with families moved along a climatic gradient from the collection area (1731 degree days, 722 mm) to the experimental area (2326 degree days; 786 mm). Datasets of morphometric, VIS-spectrometric, and germination seed data, combined with the first results of biometric data (including the Dickson quality index) of seedlings produced from these seeds, will allow scientists in the future to conduct correlation and other statistical analysis, or train a neural network to determine the presence of connections between a seed and a plant. These data contribute to the early non-destructive diag-nosis and grading of seeds according to VIS-spectrometric properties. This dataset structure can complement the FLR-Library. In the future, by tracing seedlings in their early growth (for example, over three growing seasons at the site being restored), it will be possible to determine the degree of intensification of FRM production depending on the initial properties of the seed.
Integrated multitrophic aquaculture in ponds using substrate for periphyton as natural source of food
Authors: Negri Mariana , Romera Daiane Mompean , Garcia Fabiana
Published: December 2023

As a productive and sustainable alternative to fish farmers, the present study aims to evaluate the use of substrate for periphyton growth in an Integrated Multitrophic Aquaculture (IMTA) with complementary species. The studied species were: Nile tilapia (Oreochromis niloticus), grass carp (Ctenopharyngodon idella) and curimbatá (Prochilodus lineatus). The experiment had four treatments with three replicates that evaluated the IMTAs: [T100] Cb:C – tilapia inside hapas fed on recommended feed, with grass carp and curimbatás outside the hapas making use of natural food; [T50] Cb:C – the same species distribution with tilapia fed 50 % of the daily amount of commercial diet. Cb:C 100 and Cb:C 50 – grass carp and curimbatás fed on recommended feed at two feeding rates (100% and 50%) with substrate for periphyton growth in the feeding restriction treatment. In phase II, tilapias were included in all the treatments as a complementary species. Growth performance of fish and physical-chemical parameters of water were evaluated. In the proposed models, the species were efficient in utilizing the feed and in nutrient cycling, achieving productivity of 6 t/ha in the system without water renewal. Inserting secondary and complementary species reduced the feed conversion ratio (FCR) to values of 0.95 in systems under feed restriction and 1.28 in the groups that received 100% of commercial feed. Considering the reduction of the FCR and the high productivity, farmers can diversify their products in the same area without increasing inputs.
Efektifitas Media untuk Peningkatan Pengetahuan dan Sikap pada Perilaku Hidup Bersih-Sehat Siswa Sekolah Dasar saat Adaptasi Kebiasaan Baru Era COVID-19
Authors: Niruri Rasmaya , Rakhmawati Rita , Saputri Rani Nurindah , Farida Yeni
Published: December 2023

Adaptasi kebiasaan baru pada era COVID19 dalam upaya persiapan tatap muka (PTM) untuk siswa sekolah dasar adalah perlu dilakukan, maka perlu dilakukan edukasi dalam peningkatan pengetahuan dan sikap terkait perilaku hidup bersih-sehat (PHBS). Media edukasi terdapat variasi yang digunakan untuk pendidikan jarak jauh pada pandemi COVID-19. Media yang tepat dalam pembelajaran berperan penting dalam capaian hasil belajar siswa. Tujuan penelitian ini adalah untuk mengidentifikasi perbedaan pengetahuan dan sikap terkait PHBS sebelum dan sesudah edukasi pada siswa SD dengan media video pembelajaran, video kartun animasi, dan elektronik poster (e-poster), serta mengidentifikasi perbedaan antar ketiga media edukasi dalam peningkatan skor pengetahuan dan sikap. Metode pretest-posttest design digunakan dalam mengevaluasi efektifitas media edukasi pada siswa SD di Kabupaten Pati yang bersedia turut serta dalam penelitian ini. Tiap siswa diberikan satu jenis media yang berbeda yang dipilih secara acak. Pada penelitian ini diperoleh 207 siswa. Ketiga media edukasi efektif dalam meningkatkan pengetahuan dan sikap siswa secara signifikan (p<0,05), serta terdapat pula peningkatan jumlah siswa yang termasuk kategori baik dan tidak ditemukannya kembali siswa dalam kategori kurang pada aspek pengetahuan dan sikap setelah pemberian edukasi. Peningkatan pengetahuan dan sikap paling tinggi adalah pada media video pembelajaran, dan berturut turut diikuti media video animasi dan media poster elektronik, namun keefektifitasan ketiga jenis media edukasi tersebut dalam peningkatan skor pengetahuan dan sikap tidak berbeda bermakna. Ketiga media tersebut dapat digunakan sebagai alternatif media edukasi PHBS pada siswa SD.
Hubungan Kadar Obat Gentamisin Dalam Darah Terhadap Outcome Clinic Pada Pasien Anak Yang Menderita Pneumonia Di RSUD Ajibarang
Authors: Suryoputri Masita Wulandari , Ilma Dewi Latifatul , Endriastuti Nialiana Endah
Published: December 2023

Gentamisin merupakan obat dengan indeks terapi sempit yang perlu dilakukan pemantauan kadar obat dalam darah karena dapat berpengaruh pada luaran klinis pasien. Penelitian ini bertujuan untuk mengetahui hubungan kadar gentamisin dengan outcome clinic pada pasien anak yang menderita pneumonia. Perhitungan kadar gentamisin dalam darah dapat dilakukan secara farmakokinetika berdasarkan dosis dan frekuensi pemberian obat menggunakan rumus matematika. Penelitian ini merupakan penelitian dengan desain observasional dan retrospektif. Pengumpulan data dilakukan selama 3 bulan di Instalasi Rekam Medik RSUD Ajibarang. Pengambilan data secara total sampling yang memenuhi kriteria inklusi dan eksklusi. Analisis data statistik menggunakan uji chi square untuk mengetahui hubungan kadar gentamisin dengan outcome clinic responden. Hasil penelitian ini menunjukkan terdapat 52 responden (96,3%) memiliki kadar Cssave sesuai kisaran terapi (0,5-10mg/L) dan 2 responden (3,7%) memiliki kadar Cssave tidak sesuai kisaran terapi. Dari 52 responden yang memiliki kadar Cssave sesuai kisaran terapi (0,5-10mg/L) terdapat 21 responden memberikan outcome clinic membaik dan 31 responden memberikan outcome clinic belum membaik, sedangkan 2 responden yang memiliki kadar Cssave tidak sesuai kisaran terapi terdapat 1 responden memberikan outcome clinic membaik dan 1 responden memberikan outcome clinic belum membaik. Kesimpulan: berdasarkan perhitungan estimasi kadar obat gentamisin, tidak terdapat hubungan yang signifikan antara kadar Cssave gentamisin dengan outcome clinic pasien anak penderita pneumonia di RSUD Ajibarang (p>0.05).
Antimicrobial and Phytochemistry study of Liparis resupinata Ridl. from Mount Gumitir, East Java, Indonesia
Authors: Ulum Fuad Bahrul , Setyati Dwi , Rizqoni Moh. Ikmal Alfi , Su'udi Mukhamad
Published: December 2023

Liparis resupinata Ridl. is one of the abundant epiphytic orchids in the Mount Gumitir, Jember Regency with potency for phytopharmacy study. Our study focused on the observation of the species for their antimicrobial and metabolite profiles. This study used Gram-positive and Gram-negative bacteria, i.e., S. aureus, S. typhi, and E. coli with an agar diffusion method for antibacterial activity test. The metabolite profile was generated through GC-MS. The methanolic extract of the leaves of L. resupinata showed positive antibacterial activity. The GC-MS data analysis suggested the presence of antimicrobial substances e.g., (-)-loliolide, nonanoic acid, 1,2-ethanediamine, and hydroxy dimethyl furanone.
Hubungan Kepatuhan Minum Obat terhadap HbA1C dan Kualitas Hidup Pasien Diabetes di RSI Purwodadi
Authors: Anshari Adi Fahmi , Ichsan Burhannudin , Cholisoh Zakky
Published: December 2023

Diabetes mellitus merupakan penyakit kronik yang ditandai oleh hiperglikemia. Kepatuhan minum obat pasien diabetes mellitus berpengaruh terhadap outcome klinik dan kualitas hidup mereka. Tujuan penelitian ini adalah untuk mengetahui hubungan antara kepatuhan terhadap HbA1C dan kualitas hidup pasien diabetes. Penelitian memiliki desain crossectional study dengan melibatkan pasien diabetes RSI Purwodadi sebagai sampel. Data diambil menggunakan kuesioner ProMAS untuk kepatuhan dan EQ-5D-5L untuk kualitas hidup. Pengambilan dilakukan pada Maret-April 2023. Sampel yang memenuhi kriteria inklusi yaitu pasien terdiagnosa minimal selama 2 tahun, rutin menggunakan antidiabetes oral dan terdaftar sebagai peserta BPJS. Jumlah responden yang terlibat dalam penelitian sebanyak 79 orang yang didominasi perempuan (72%). Uji Chi-Square tidak terdapat hubungan antara profil responden dengan kepatuhan (p>0,05). Kepatuhan terhadap HbA1C dan kualitas hidup memiliki hubungan yang signifikan (p<0,05). Uji korelasi Spearman rho menunjukkan bahwa tingkat hubungan memiliki kekuatan sedang (>0,5). Kepatuhan terhadap HbA1Cdan kualitas hidup pasien diabetes mellitus memiliki hubungan yang signifikan.
PERFORMANCE PROPERTIES OF MARINE FUEL DERIVED FROM SECONDARY POLYMER RAW MATERIALS
Authors: Chernyavsky Andriy , Grigorov Andriy
Published: December 2023

The article substantiates the need to determine the operational properties of shipping fuel obtained from secondary polyolefin (HDPE and PP) raw materials by catalytic pyrolysis. It is proposed to evaluate the operational properties of fuel for shipping – marine gasoil (MGO) by the value of the cetane index (CI, unit), H:C ratio, working heat of combustion (Q, MJ/kg). In view of the scheme of catalytic pyrolysis of polymeric raw materials proposed by us, which consists of two stages (I stage - the course of reactions on a mixture (1:1) of zeolitecontaining catalysts Zn-H-ZSM-5/Fe-H-ZSM-5; II stage – the course of reactions on the NiH-ZSM-5 catalyst), it is necessary to determine after each stage of the process the quality indicators of the reaction products (fractions with boiling points of -360(380) °С) given above. Also, additionally, we determined the quality indicators for the fractions obtained on the H-ZSM-5 industrial catalyst. The proposed research program, on the one hand, allows to determine the efficiency of the pyrolysis process with the selected catalysts in comparison with industrial technology, on the other hand, it will allow to adjust the process in the direction of obtaining a final product of a quality level that meets the requirements for MGO presented in ISO 8217:2017. The conducted studies showed that by the value of CI (48-50 units) and ν 40 (2,8–3,1 mm²/s) the fractions with boiling points of 180–360(380) °С, which were obtained by pyrolysis of polymer raw materials according to the two-stage technology proposed by us (on Zn-H-ZSM-catalysts 5/Fe-H-ZSM-5, Ni-H-ZSM-5) can be attributed to the brands of distillate marine fuels DMA, DFA, DMZ, DFZ (ISO 8217:2017). These fractions are also characterized by a high Н:C ratio (for HDPE – 1.62; for PP – 1.64) and working heat of combustion (for HDPE – 44.0 MJ/kg; for PP – 44.3 MJ/kg), which makes it possible to use them as fuels for shipping.
ANALYSIS OF WASTE GAS CLEANING METHODS FROM SULFUR DIOXIDE
Authors: Dzevochko O. , Podustov M. , Dzevochko A. , Pashko A.
Published: December 2023

It is shown that sulfur dioxide is one of the most common components of harmful emissions into the atmosphere.

It is presented that a large amount of SO2 is emitted into the atmosphere in the production of sulfuric acid, during the combustion of fuel in thermal power plants, in modern production of surfactants.

Sulfur dioxide has been shown to be responsible for the formation of acid rain, which is one of the most common forms of pollution worldwide.

The transport of sulfur compounds over long distances leads to the deposition of sulfur dioxide in soils and waterways.

It is known that all known methods of waste gas purification are divided into three main groups: ammonia methods, SO2 neutralization methods, catalytic methods.

In the general case, absorption methods are divided into open and circulating cleaning schemes.

It is shown that ammonia-acid methods are economical, but require the cost of a scarce product – ammonia.

The ammonia-sulfuric acid method consists in the treatment of ammonium bisulfite with sulfuric acid.

When using the ammonia-phosphorus-acid method, phosphorus methods and sulfuric acid are formed.

The soda method is based on the absorption of sulfur dioxide by a suspension of CaO.

The lime method is based on the absorption of sulfur dioxide by a suspension of CaO.

It is shown that when using a sodium hydroxide solution as an absorbent, both open-loop and circulating cleaning schemes are used.

Open circuits are characterized by simple hardware design, as well as low energy for cleaning.

It has been shown that catalytic methods for cleaning exhaust gases do not require the use of an absorbent. However, it is necessary to use an expensive catalyst. More often, this method is used at the first stage of cleaning, and at the second – the above methods of cleaning.

A table with comparative technical and economic indicators is given.

It is shown that for the production of surfactants it is better to use open-loop purification schemes.

It is suggested that sodium hydroxide solution can be chosen as the absorbent. With the content of small amounts of sodium sulfite in a solution of sodium hydroxide, it can be used as a neutralizing agent in the neutralization of sulfation products.
EXAMINATION OF EXPERIMENTAL DATA SAMPLES FOR THE PRESENCE OF OUTLIERS: COMPARISON OF METHODS
Authors: Potanina T. V. , Mykhaylenko I. V.
Published: December 2023

The task of detecting outliers (misses, abnormalous values, results that stand out sharply, results that have come off) is one of the most relevant, complex and ambiguous in the experimental materialprocessing. Such values are the experiment results, which are abnormally far from other points from a series of parallel observations.

The source of emissions is often measurement errors. Among these are incorrect recording of the experiment results, possible incorrect coding of data, incorrect conduct of the experiment, etc. Gross errors occur in the event of a sudden change in the conditions of conducting the research, malfunctions in the operation of the equipment, etc.

At the same time, outliers may indicate an unexpected, extraordinary behavior of the measured value – a yet-to-be-explained property process manifestation. And that's why an analysis using reliable mathematical tools is needed.

The methods of detecting emissions are diverse and numerous. Parametric tests are more sensitive to the sample size and to the population values probability distribution. Non-parametric tests are more flexible and can be applied if the non-normal distributon of the sample or the sample size is small; such criteria give a better result in asymmetric distributions, because they use the median instead of the mean; they can be applied to ordinal or nominal data, as well as in the situation of an aberrant outlier value.

Interval analysis methods, in particular interval statistics, are an alternative flexible toolkit for obtaining a more accurate and complete analysis of experimental data in the incomplete information, noise presence, measurement outliers, and the presence of abnormalous and aberrant points.

A comparison of the results of the application of parametric criteria (-criterion, -criterion, Lvovskyi) and non-parametric criteria (the box-and-whiskers-plot) for detecting emissions, as well as calculation using interval statistics methods, was carried out. One of the outliers was determined by the non-parametric criterion, the -criterion and the procedure for detecting a single outlier using interval methods. Two values are suspicious outliers using the box-whisker rule and the interval statistics recognition algorithm.

The methods of detecting outliers using interval analysis methods are no less effective than the use of non-parametric tests.
The Association between Frailty and Frequency of Eating Alone among Korean Older Adults
Authors: Jo Eun Young , Choi Gi Eun , Nam Jin Young
Published: December 2023

Objectives: This study aimed to explore the relationship between frailty and frequency of eating alone among older adults in Korea.Methods: We used data from the Korean National Health and Nutrition Examination Survey from 2014 to 2019, focusing on individuals aged 65 years and older. Frailty was assessed using Fried phenotype of frailty criteria. A multiple logistic regression analysis was conducted to assess the relationship between frailty and frequency of eating alone.Results: Among 9,031 older adults, those in the 65-74 age group (young-old) who ate alone every meal had a 1.4-folds higher risk of frailty compared to those who did not eat alone (odds ratio, OR = 1.4, 95% confidence interval, CI = 1.06-1.90). Particularly, women aged 65-74 who ate alone every meal had a 1.5-folds higher risk of frailty compared to those who did not eat alone (OR = 1.5, 95% CI = 1.06-2.01).Conclusions: This study reveal a significant relationship between frailty and the frequency of eating alone among older adults. Specially, young-old women who ate alone were found to be more vulnerable to frailty than those who did not. Therefore, government policies should be implemented to support older people living alone in order to mitigate their risk of frailty.
Распространение вариантов вируса SARS-COV-2, вызывающих интерес (VOI) и находящихся под наблюдением (VUM), на основе количества их геномов, депонированных в базу данных GISAID за неделю с 2 по 8 декабря 2023 г.
Authors: Дмитриева Людмила , Краснов Ярослав , Чумачкова Елена , Осина Наталья , Зимирова Анастасия , Иванова Александра , Карнаухов Игорь , Караваева Татьяна , Щербакова Светлана , Кутырев Владимир
Published: December 2023

В обзоре представлена информация по циркулирующим в настоящее время вариантам вируса SARS-COV-2 Omicron вызывающих интерес (VOI) и находящихся под наблюдением (VUM), геномные последовательности которых размещены в международной базе данных GISAID за неделю с 2 по 8 декабря 2023 г.
Анализ динамики эпидемического процесса COVID-19 в мире за неделю с 02.12.2023 г. по 08.12.2023 г.
Authors: Зимирова Анастасия , Поспелов Михаил , Иванова Александра , Дмитриева Людмила , Чумачкова Елена , Карнаухов Игорь , Щербакова Светлана , Кутырев Владимир
Published: December 2023

В обзоре представлен анализ эпидемиологической ситуации в странах мира по COVID-19 за неделю с 02.12.2023 г. по 08.12.2023 г.
Combined Lateral Closing and Medial Opening-Wedge Proximal Humerus Osteotomy in an Adolescent with Extreme Varus Deformity
Authors: Oeding Jacob F. , Jacobson Nathan J. , Wentworth Adam J. , Sems Stephen A. , Stans Anthony A. , Barlow Jonathan D.
Published: December 2023

Case:

This report describes the case of an athletic 12-year-old boy who presented with a 64° left proximal humeral varus angulation deformity and physeal bar secondary to multiple operations for a proximal humeral metaphyseal cystic lesion and pathologic fracture. Using a combined lateral closing and medial opening-wedge osteotomy, a 68° valgus correction was achieved with excellent clinical and functional outcomes at 16-month follow-up. Forward flexion increased from 120 to 170° preoperatively to postoperatively while abduction improved from 110° preoperatively to 170° postoperatively.

Conclusion:

A combined lateral closing and medial opening-wedge osteotomy of the proximal humerus can successfully treat cases of extreme proximal humerus varus in the growing shoulder where unilateral or dome osteotomies are not suitable.
The impact of the Covid-19 vaccination policy in Mexico. A quasi-experimental effectiveness evaluation of a multi-vaccine strategy
Authors: Bautista-Arredondo Sergio , Cerecero-García Diego , Macías-González Fernando , Barrientos-Gutiérrez Tonatiuh
Published: December 2023

Objective. To assess the impact of a vaccination campaign that administered five different technologies in a middle-income country with one of the largest Covid-19 epidemics. Materials and methods. Using data from Mexico’s Epidemiological Surveillance System for Viral Respiratory Disease (Sisver) and the design of the vaccine policy in Mexico as a natural experiment, we applied difference-in-differences econometric methods to assess the strategy’s effectiveness on transmission, hospitalizations, and mortality rates among adults 60 to 64 years old in Mexico between April and June 2021. Results. We estimated average effectiveness levels of 60.9% against confirmed cases of Covid-19. Vaccination also decreased hospitalizations and deaths by 62.7 and 62.6%, respectively. After adjusting for vaccination coverage, we found an impact of 79.1, 80.9, and 81.3% reduction in new cases, hospitalizations, and deaths among the vaccinated. Conclusion. Despite the significant progress in our knowledge of Covid-19 vaccination effectiveness, the available evidence relies mostly on experiences from high-income countries. This study contributes to the scientific literature of Covid-19 vaccination effectiveness in a middle-income country with a multi-vaccine scheme.
Prophylactic cancer vaccines: development and challenges for HBV and HPV vaccines in Latin America
Authors: Ramírez-López Laura Ximena , Carnalla-Cortés Martha , Barrientos-Gutiérrez Tonatiuh , Coursaget Pierre , Muñoz Nubia
Published: December 2023

Vaccines against hepatitis B virus (HBV) and human papillomaviruses (HPV) are two safe and highly effective vaccines that were developed at the end of the 20th century and can prevent human cancer. HBV vaccine prevents liver cancer, and HPV prevents cervical and other HPV-related cancers. Starting with the immunogen identification, 15 years were necessary to reach the industrial production of HBV vaccine, and 20 years, for the HPV vaccines. However, while HBV vaccines have been commercially available for over 40 years and are used in most countries, there are still significant challenges to achieve universal childhood immunization against hepatitis B. Similarly, HPV vaccines have been commercially available for 17 years, and yet, countries with higher cervical cancer still have the lowest HPV vaccination rates. We describe the development of HBV and HPV vaccines and discuss the challenges to reaching equitable access to these vaccines in Latin America.
Design and implementation of AMBAR: an innovative evidence-based training program for childbirth and newborn care
Authors: Fritz Jimena , Treviño-Siller Sandra , Sánchez-Domínguez Mario , González-Hernández Dolores , Bishop Alina , Lamadrid-Figueroa Hector
Published: December 2023

Objective. To present the development of a training model called AMBAR (Atención a la mujer embarazada y al recién nacido [Care for pregnant women and newborns]), which was designed to improve the quality of attention of health personnel responsible for obstetric care. Materials and methods. AMBAR was designed based on the results of a qualitative study exploring public health providers’ needs and experiences. It was implemented in three health networks, and a total of 339 health personnel participated. Results. The educational design of the course was appealing to the trained personnel, and the inclusion of simulations in all modules encouraged interest, participation, as well as the integration of new knowledge and skills into practice. Conclusion. AMBAR can promote better practices and increase the quality of birth care. With the proper support and willingness of staff and management, AMBAR can be implemented in all health services, both public and private.
Implementation of a population-based cancer registry network in Mexico 2017-2020
Authors: Mohar Alejandro , Paredes Andrea , Brau-Figueroa Hasan , Sánchez Alejandro , Palafox Alejandra , Rivera-Gómez Rebeca , Pech Kristal , Carranza-Matus Mario , Arrieta Oscar , Inchaustegui Andrea , Moreno Elena , Piñeros Marion
Published: December 2023

The growing cancer burden particularly among less developed countries requires local data to plan and evaluate cancer control measures. This article describes the development of a population-based cancer registry network (PBCRN) in Mexico that took place between 2017 and 2020 and present related data. The PBCRN, led by the National Cancer Institute (Incan), included nine registries representing 11.3% of the Mexican population. Definitions, coding, and operative processes were based on international standards. All cities were visited to set up local structure; personnel were hired by Incan and trained in basic cancer registration in Merida. A specific software was developed. Regular virtual meetings took place for data verification and quality control. Data collection included institutions of the public and private health system. Personnel included 34 registrars, nine local leaders, and 12 staff members at the Incan. A total of 13 517 cases were recorded between 2017-2020, 64% percent of them were among females. Breast cancer was the more frequent malignancy (23.3%), followed by digestive organs with (18.4%) and female genital cancers (13.5%). Childhood (0-14 years) and adolescents cancer represented 4.4% of the total new cancer cases. The network was suspended in 2020. The present effort lacked sustainability and data were only partial. However, the experience provides valuable insights to be considered for the renewed cancer registration efforts that are currently ongoing in Mexico.