bluuebunny/crossref_metadata_2025 huggingface dataset:
Верификация памятников археологии открытых экспедициями под руководством В.В.Гольмстен (на примере «курганника у села Домашка»)
Authors: Вальков Денис Владимирович , Большакова Наталья Владимировна , Кошутин Роман Андреевич , Пинигин Глеб Валерьевич
Published: April 2022

Статья посвящена поиску курганного могильника, исследованного в 1926 г. членами Самарского Общества археологии, истории, этнографии и естествознания под общим руководством В.В. Гольмстен. К находкам из этого памятника относится уникальный медный котел позднего бронзового века. За истекшие годы информация о местоположении этого памятника была утрачена. Для его поиска были проведены: анализ архивных и современных космических снимков, пространственный анализ, анализ цифровой модели рельефа. Результаты проверены полевой разведкой. Впервые для поиска степных курганов удачно использована тепловизионная съемка с БПЛА. Убедительная верификация памятника на местности позволяет использовать данную комплексную методику для поиска ранее открытых, но считающихся утраченными памятников археологии Поволжья.
Цилиндрическая печать из историко-краеведческого музея г. Джалилабада (Азербайджанская Республика)
Authors: Кириченко Дмитрий Александрович
Published: April 2022

В статье рассмотрена цилиндрическая печать из экспозиции историко-краеведческого музея (Инв. № 4240) г. Джалилабада (Азербайджанская Республика). Печать изготовлена из пасты с резным орнаментом. Цвет изделия белый. Размеры: высота – 3,2 см, ширина – 0,9 см. Артефакт был обнаружен близ с. Адналы и, вероятно, происходит из разрушенного погребения. На оттиске печати имеется изображение сцены охоты. Цилиндрическая печать из Адналы относится к так называемому «общему/обычному» стилю митаннийских цилиндрических печатей. Артефакт, предположительно, датируется, в пределах первой трети I тыс. до н.э. Аналогии печати из Адналы можно встретить в синхронное время на территории Ближнего Востока. В частности, близкая сюжетная композиция печати из Адналы представлена на оттисках/печатях из Хасанлу IVB («местный» стиль цилиндрических печатей) с территории Ирана, а также из Нимруда, Ашшура (Ирак), Алалаха (Турция), а также на печати из коллекции Маркополи (предположительно, обнаружена в Ираке). Цилиндрическая печать из Адналы свидетельствует о контактах местного населения юга Азербайджана в эпоху поздней бронзы – раннего железа с культурными центрами Ближнего Востока.
Common c.-32-13T>G mutations of the acid α-glucosidase gene in Pompe disease: an updated literature review
Authors: Ezzat Aly , ElBagoury Marwan , Roushdy Sherif , Aktham Yahia
Published: April 2022

Pompe disease is a multisystemic metabolic rare disease caused by the deficiency of the lysosomal enzyme acid-α-glucosidase (GAA) leading to progressive muscle weakness, organomegaly, respiratory failure, and ultimately death. The inotropic c.-32-13T > G mutation is a commonly reported mutation among cases with late-onset Pompe disease and presents in 40%-90% of the cases, with predominance among Caucasian Populations. In addition, c.1856G > A missense mutation effectively reduces GAA activity and is associated with an intermediate disease course.
To date, the mechanisms by which the c.-32-13T > G mutation affects GAA mRNA splicing and c.1856G > A affects GAA activity are not fully known. Therefore, this manuscript reviews the current literature describing the frequency of c.-32-13T > G and c.1856G > A variation in Pompe disease patients and the mechanisms underlying these variations.
CLINICOPATHOLOGICAL ANALYSIS OF ODONTOGENIC KERATOCYSTS: 10 YEARS EXPERIENCE FROM A SINGLE CENTER
Authors: YILMAZ Fatih , DERECİ Ömür , SARUHAN Nesrin , AÇIKALIN Fuat
Published: April 2022

Objective: The aim of the study is to update our understanding of the clinicopathological features of odontogenic keratocysts in a series of 43 cases from a single center.Material and Methods: This retrospective study included 51 specimens from 43 patients diagnosed between 2010 and 2020. Microscopic findings, patients’ age, gender, lesion location, and presence or absence of recurrence were noted.Results: The study group included 22 men and 21 women with a mean age of 38.72 /year. In 37 patients, the lesion occurred in the mandible, while in 6 patients it was found in the maxilla. Three patients were associated with nevoid basal-cell carcinoma syndrome. Three patients had multiple odontogenic cysts. Satellite cysts were present on the cyst walls in 5 of the 43 cases. Epithelial islands were present in 4 of the cases. In 28 cases, moderate to severe inflammation was observed in the cyst wall. Among them, in 18 cases, classical odontogenic keratocyst features were lost in some areas in the cyst epithelium. Elongation of rete ridges and radicular cyst-like areas were observed in 12 cases. In only 41.66% of patients, the odontogenic keratocyst or keratocystic odontogenic tumor terms were given in the provisional diagnoses. Clinically, the most frequently confused lesions in the differential diagnosis were dentigerous cyst, radicular cyst, residual cyst, and ameloblastoma. No recurrence was observed in any of the patients.Conclusion: Concomitant inflammation can cause changes in the epithelium and may hide the diagnostic features of odontogenic keratocysts. Therefore, careful examination is required for accurate diagnosis.
ORTA ANADOLU TOPLUMUNDA ALT ÇENE KÜÇÜK AZI DİŞLERİNİN KÖK KANAL MORFOLOJİSİNİN VE KRON-KÖK ORANININ KONİK IŞINLI BİLGİSAYARLI TOMOGRAFİ İLE DEĞERLENDİRİLMESİ
Authors: TÜRKYILMAZ Ali , AYDOĞDU Merve , ADIŞEN Mehmet Zahit , ALTINDAĞ Ali
Published: April 2022

Amaç: Bu retrospektif çalışmanın amacı, alt çene küçük azı dişlerinin kök kanal anatomisinin yapısal konfigürasyonlarını ve kron-kök oranını cinsiyete, yaş aralıklarına ve bilateral uyum varlığına göre konik ışınlı bilgisayarlı tomografi kullanarak incelemektir.Gereç ve Yöntemler: Toplam 300 hastanın alt çene birinci ve ikinci küçük azı dişlerinden 1200 adet konik ışınlı bilgisayarlı tomografik görüntüsü elde edildi. Görüntüler; i) kök kanal konfigürasyonlarının morfolojisi, ii) kron uzunluğu, iii) kök uzunluğu, iv) toplam diş uzunluğu, v) kron-kök oranı; cinsiyet, yaş ve bilateral uyuma göre değerlendirildi. Veriler bağımsız örneklem t-testi ve tek yönlü varyans analizi (ANOVA) ile analiz edildi. p<0.05 değeri anlamlı kabul edildi.Bulgular: Hem alt çene birinci küçük azı dişleri hem de ikinci küçük azı dişlerinde cinsiyet, yaş ve simetrik karşılaştırmalarda anlamlı farklılıklar gözlendi (p<0.05). İncelenen dişler Vertucci sınıflandırmasına göre Tip I’den Tip VI’ya kadar altı farklı kök kanal konfigürasyonu gösterdi. Kron uzunluğu, kök uzunluğu, toplam diş uzunluğu ve kron-kök oranı bakımından yaş aralıklarının karşılaştırılmasında anlamlı farklılık bulundu (p<0.05).Sonuç: Alt çene birinci küçük azı dişlerinde, iki kanal bulunma sıklığı ikinci küçük azı dişlerinden yaklaşık iki kat daha fazlaydı. Yaşla birlikte kron uzunluğu ve kron-kök oranı azalırken, kök uzunluğunun arttığı belirlendi.
COMPARISON OF INFECTED LUNG VOLUME OF COVID-19 PATIENTS AND THEIR CLINIC AND LABORATORY DATA
Authors: KÖKSAL Murathan , ÖZKAN Erdem , GÜLBAY Mutlu , AYBAR BİLİR Yeşim , AKINCİ Esragül , AYPAK Adalet , GÜNER Hatice Rahmet
Published: April 2022

Objective: In this study, it was aimed to evaluate the healthy and infected area volumes and elementary lesion characteristics in thorax computed tomography examinations of mild-moderate and severe patient groups according to the clinical severity scoring determined by the World Health Organization, and to compare the obtained findings with laboratory and clinical data.Material and Methods: A total of 100 cases (59 males, 41 females; age range 18-95 years) were retrospectively and randomly selected from the patients who had non-contrast thoracic computed tomography scan and were diagnosed with Covid-19 pneumonia by reverse transcription polymerase chain reaction test. According to clinical severity scoring, patients were classified as mild-moderate and severe groups. Volumetric measurements were made in the lungs using quantitative analyses. In addition, lesion characteristics (ground glass opacity, consolidation, air bronchogram) in the infiltration areas were recorded. The relationship between radiological findings and clinical-laboratory data was statistically evaluated.Results: The age of the patients ranged between 58.80±14.74 years; 52% of the cases were in the severe category, 48% of them were in the mild-moderate category. Lung volumes did not differ significantly between disease groups. According to computed tomography findings, there was a statistically significant correlation between subpleural reticulations and air bronchogram and disease groups. IL-6, D-dimer, ferritin, neutrophil lymphocyte ratio and C-Reactive Protein values were higher in the severe disease group than in the mild-moderate group.Conclusion: Volumetric values associated with laboratory parameters are thought to be an important indicator of the immune response that determines the course of the disease.
HEMŞİRELERİN TIBBİ HATA YAPMA EĞİLİMLERİ: BİR KAMU ÜNİVERSİTESİ TIP FAKÜLTESİ HASTANESİ ÖRNEĞİ
Authors: ÇELİK DURMUŞ Serpil , ERDEM Yurdagül , DOĞAN YILMAZ Esra
Published: April 2022

Amaç: Bu çalışma, bir kamu üniversite hastanesinde çalışan hemşirelerin tıbbi hata yapma eğilimlerini belirlemek amacıyla tanımlayıcı olarak yapıldı.Gereç ve Yöntemler: Çalışmanın örneklemini, bir kamu üniversitesi hastanesinde çalışan ve araştırmaya katılmaya gönüllü 78 hemşire oluşturdu. Veriler, Demografik Bilgi Formu ve Hemşirelerin Tıbbi Hataya Eğilim Ölçeği ile toplanmıştır. Ölçek, 49 madde, 5 alt boyuttan oluşmaktadır (min: 49; maks:245). Ölçeğin puan ortalaması yükseldikçe hemşirelerin tıbbi hata yapma eğiliminin düşük olduğu kabul edilmektedir. Veriler, ortalama ve yüzdelik hesaplamaları, Kruskal-Wallis testi ve Mann-Whitney U testi ile değerlendirilmiştir.Bulgular: Araştırmaya katılan hemşirelerin yaş ortalaması 32.44 ±7.11, %70.5’i kadın olup %26.9’u daha önce tıbbi hata yaptığını belirtmektedir. Hemşirelerin tıbbi hata yapma eğilim ölçeğinden aldıkları puan ortalamalarına göre, ilaç ve transfüzyon uygulamaları 84.84±5.29; hastane enfeksiyonlarının önlenmesi 55.66±4.83; hasta izlemi malzeme ve cihaz güvenliği 39.57±6.71; düşmelerin önlenmesi 21.96±4.26; iletişim 22.83±3.69; tıbbi hata yapma eğilim ölçeği toplam puan ortalaması 224.88±19.65’tir. Çalışılan birime göre düşmelerin önlenmesi alt boyutunda, cerrahi bilimlerde çalışan hemşirelerin puan ortalamasının en düşük (19.82±5.02) olduğu belirlenmiştir.Sonuç: Çalışmada, hemşirelerin genel olarak tıbbi hata yapma eğilimlerinin düşük olduğu, ancak iletişim ve düşmelerin önlenmesi boyutunda hemşirelerin tıbbi hata eğiliminin yüksek olduğu ve cerrahi kliniklerde çalışan hemşirelerin tıbbi hataya eğiliminin yüksek olduğu saptandı.
A THREE-YEAR RETROSPECTIVE ANALYSIS OF VAGINITIS AGENTS IN PATIENTS ADMITTED TO A PRIVATE HOSPITAL
Authors: ÜNLÜ Özge , ÇAĞLAR Tülay , ERDEM Mustafa Genco , EKİCİ Seda , DEMİRCİ Mehmet
Published: April 2022

Objective: In this study, we aimed to present the pathogens detected as vaginal infection agents isolated from vaginal swab samples in adult patients admitted to the Department of Gynecology and Obstetrics of a private hospital in Istanbul for three years retrospectively.Material and Methods: Vaginal swabs of adult non-pregnant patients admitted to Gynecology and Obstetrics outpatient clinics of a private hospital in Istanbul between 2016-2018 were included in this study. The samples were transferred quickly to the laboratory after sampling, and the infectious agents were identified with conventional bacterial culture methods.Results: Identification results of 314 vaginal swab samples revealed that 28 (8.92%) had C. albicans, 13 (5.73%) had pathogens that cause aerobic vaginitis, and five (1.59%) had bacterial vaginosis agents. C. albicans was the highest among agents with a frequency of 8.92%, followed by E. coli (2.23%).Conclusion: Our retrospective analysis revealed that C. albicans is the most frequent pathogen causing vaginitis in our hospital. As the pathogens causing vaginitis vary from region to region, we believe that monitorization of the epidemiological data is important.
KOMPLİKE OLMAYAN SELÜLİT VAKALARINDA FARKLI TEDAVİ SEÇENEKLERİNİN DEĞERLENDİRİLMESİ
Authors: ERTUNÇ Barış , ARSLAN Mustafa
Published: April 2022

Amaç: Günlük pratiğimizde sıklıkla karşılaştığımız selülit vakalarında kullanımı önerilmekte olan seftriaksonun, yarı ömrünün uzun olması nedeni ile kılavuzlarda günde tek doz olarak kullanılabileceği belirtilmekle birlikte zaman zaman tedavide sorunlar ile karşılaşabilmekteyiz. Bu nedenle günde tek doz seftriakson tedavisinin etkinliğinin diğer ajanlarla karşılaştırılarak değerlendirilmesi amaçlandı.Gereç ve Yöntemler: Çalışmamıza 2017 - 2019 yılları arasında hastanemizde tedavi edilmiş ve komplike olmayan 46 selülit hastası dahil edilmiştir. Hastalara ait demografik, klinik ve laboratuvar verileri hasta dosyalarından elde edildi. Mann-Whitney U ve Kruskal-Wallis testleri ile veriler değerlendirildi. p<0.05 olan değerler istatistiksel olarak anlamlı kabul edildi.Bulgular: Hastalar sefazolin, seftriakson günde 2 kez ve seftriakson günde bir kez alanlar olacak şekilde sırası ile Grup-1, Grup-2 ve Grup-3 olarak gruplara ayrıldı. Grup-1 ve 2 arasında klinik cevap ve toplam tedavi süresi arasında anlamlı farklılık bulunmamakla birlikte Grup-3’te; Grup-1 ve 2’ye göre klinik cevap ve tedavi süresi daha uzun ve istatistiksel olarak anlamlı idi.Sonuç: Seftriaksonun günde tek doz kullanımı önerilmekle birlikte, sefazolin ve günde 12 saat ara ile uygulanan seftriakson tedavileri ile karşılaştırıldığında klinik cevabın daha geç alındığı görülmüştür. Bu hastalarda toplam tedavi süresi de daha uzun olmakta idi. Bu nedenle seftriaksonun tedavi başlangıcında 12 saat ara ile başlanmasının daha uygun olacağı görüşündeyiz.
THE EFFECT OF MANDIBULAR CONDYLE SIZE ON DISC DISPLACEMENT AND GENDER RELATIONSHIP
Authors: YOKUŞ Adem
Published: April 2022

Objective: Our aim in this study is to analyze the association between anterior disc displacement and mandibular condyle size. It was also aimed to examine the influence of gender factor on condyle size.Material and Methods: Images of patients who underwent magnetic resonance imaging of the temporomandibular joint in the radiology department between January 2018 and November 2021 were analyzed retrospectively. The articular disc was evaluated in terms of displacement on sagittal oblique images in closed and open mouth positions. Following, anteroposterior and mediolateral dimensions were measured at the head of the mandibular condyle.Results: Among the 200 individuals in the study, 44 were male and 156 were female. A total of 400 temporomandibular joints of 200 patients were analyzed. In 279 joints, the disc was in its normal position, and there was no disc displacement. There was disc displacement with reduction in 54 joints and disc displacement without reduction in 67 joints. The anteroposterior and mediolateral sizes of the mandibular condyle were higher in the group with normal disc position compared to the groups with disc displacement. In the disc displacement without reduction group, the mean values of anteroposterior and mediolateral dimensions were the lowest (p=0.001). Male individuals had a mandibular condyle anteroposterior size of 6.706±2.588 cm while female subjects had a size of 5.786±1.288 cm, which was significantly lower in females (p=0.001). Mandibular condyle mediolateral size was 18.779±2.848 cm in male subjects, 17.016±2.290 cm in female subjects, and was significantly lower in females (p=0.001).Conclusion: We determined that the mandibular condyle size was smaller in joints with anterior disc displacement than in joints with normal disc position. In addition, we observed that the condyle size was significantly lower in females than in males. Low mandibular condyle size may be a risk factor for anterior disc displacement.
A COMPARATIVE ASSESSMENT OF TRANSESOPHAGEAL AND TRANSTHORACIC ECHOCARDIOGRAPHY FOR ANALYSIS OF RIGHT VENTRICULAR DEFORMATION
Authors: DEMİR GÜNDOĞMUŞ Pınar , KALKAN Kamuran , AKSU Uğur , AKSAKAL Emrah , BİRDAL Oğuzhan
Published: April 2022

Objective: The transthoracic echocardiography (TTE) is the primary method to evaluate the right ventricular (RV) functions, but the assessment of the RV by TTE can be difficult due to the complex structural and anatomical position of the RV. The transesophageal echocardiography (TEE) is a good alternative to TTE when faced with difficulties in obtaining images. In this study, we investigated the agreement between TTE and TEE for the evaluation of the RV functions.Material and Methods: This study was carried out on 78 patients between January 2017 and May 2017. The TTE and TEE records of the patients were compared by using Bland Altman analysis, and the mean difference and confidence interval between them were analyzed.Results: Seventy-eight patients were involved in this study. The mean age of patients was 42 years, and 34% of the participants were female. In Bland Altman analysis, there was a moderate agreement between TTE and TEE in terms of mean difference of the E velocity, the A velocity, E’, A’. In contrast, there was a good agreement between TTE and TEE in terms of mean difference of RV strain, RV strain rate E, RV strain rate A, RV strain rate S which means that it could be appropriate to use them interchangeably.Conclusion: The deformation parameters are essential for analyzing the RV functions, making a clinical decision, and estimating adverse events. The deformation parameters measured using TEE may yield information as accurate and useful as those measured using TTE, and they may be used interchangeably in making a clinical decision.
HİPERTANSİF SOL VENTRİKÜL HİPERTROFİSİNİN VENTRİKÜLER REPOLARİZASYON ÜZERİNE ETKİSİ
Authors: EREN Hayati , GÜRBÜZ Ahmet Seyfeddin , KAYA Ülker
Published: April 2022

Amaç: T dalgasının tepe ve sonu aralığı (Tp-e), Tp-e/QT oranı ve Tp-e/QTc oranı ventriküler repolarizasyonun yeni indeksleridir ve ventriküler aritmiler ile ilişkilendirilmiştir. Hem hipertansiyon hem de sol ventriküler hipertrofi varlığının ventriküler aritmi gelişimi ve ani kardiyak ölüm için bir risk faktörü olduğu bilinmektedir. Bu çalışmada, hipertansiyon hastalarında sol ventriküler hipertrofi varlığının Tp-e aralığı, Tp-e/QT oranı ve Tp-e/QTc oranı üzerindeki etkisini belirlemeyi hedefledik.Gereç ve Yöntemler: Yeni tanı alan 346 hipertansiyon hastası çalışmaya dahil edildi. Hipertansiyon hastaları ekokardiyografik sol ventriküler hipertrofi varlığına göre iki gruba ayırıldı. Daha sonra yaş ve cinsiyet eşitlemesi yapılan 175 kontrol hastası belirlendi. Tüm hastaların Tp-e aralığı, Tp-e/QT ve Tp-e/QTc oranları, QT ve QTc değerleri 12 derivasyonlu elektrokardiyografi ile ölçülerek gruplar arasında karşılaştırıldı.Bulgular: Her üç grup arasında bazal özellikler açısından istatistiksel olarak anlamlı bir fark bulunmadı. Tp-e aralığı, Tp-e/QT ve Tp-e/QTc oranının sol ventriküler hipertrofi gelişen hipertansiyon grubunda hem kontrol gurubuna göre hem de sol ventriküler hipertrofi olmayan hipertansiyon grubuna göre daha uzun olduğu tespit edildi. Benzer şekilde geleneksel parametreler olan QT ve QTc değerlerinin de sol ventriküler hipertrofi olan grupta diğer iki gruba göre uzun olduğunu tespit ettik.Sonuç: Çalışmamız hipertansiyon hastalarında sol ventriküler hipertrofi varlığının Tp-e aralığı, Tp-e/QT ve Tp-e/QTc oranlarını arttırdığını ortaya çıkarmıştır. Sonuçlarımız hipertansiyon hastalarında aritmi gelişimi için ana risk faktörlerinden birisinin sol ventriküler hipertrofi varlığı olduğunu göstermektedir.
İNHALER İLAÇ KULLANIMINA BAĞLI ORAL YAN ETKİLER: DOĞRU BİLİNEN BİR YANLIŞ MI?
Authors: ZORLU Duygu , SAYLAM Mehmet
Published: April 2022

Amaç: Kronik solunum yolu hastalıklarında, oral ve dental sorunlar önemli bir komorbidite nedeni olarak görülmektedir. Oral ve dental sorunların en önemli nedeni olarak yaygın görüş ise inhaler ilaçlardır. Bu görüş hastaların ilaçları uygun süre, dozda almamalarına ve tedavinin tam sağlanamamasına neden olmaktadır. Bu nedenle, çalışmamızın amacı, kronik solunumsal hastalığı nedeniyle inhaler ilaçlar kullanan hastalarda, oral-orofarengeal, dental bulguları değerlendirmek ve ilaç kullanım uyumunu artırmayı sağlayabilmektir.Gereç ve Yöntemler: Çalışma 2020 Nisan ayı boyunca 300 hastanın sorgulanması ile yapılmıştır. Çalışma göğüs hastalıkları poliklinik başvurusu olan, rastgele seçilen ve çalışma dahil edilme kriterlerini sağlayan 33 hasta ve ağız-diş sağlığı poliklinik başvurusu olan rastgele 24 katılımcıdan oluşan kontrol grubu ile gerçekleştirilmiştir.Bulgular: Çalışmaya katılan hastaların, %57.6’sı erkek, %42.4’ü kadın idi. İnhaler ilaç kullanan hastaların %3’ü Astım- Kronik Obstrüktif Akciğer Hastalığı Overlap sendromu, %33.3’ü Astım, %63.6’sı da Kronik Obstrüktif Akciğer Hastalığı tanısı ile takip edilmekteydi. Hastaların yaş ortalaması 57.6 idi. Bu hastaların %54.5’i 5 yıldan daha az, %45.5’i ise 5 yıldan uzun zamandır inhaler ilaç kullanmaktaydı. Hastaların diş hekimi muayenesinde %97’sinde peridental bulgular, %78.8’inde en az bir dental çürük, %12.1’inde orofarengeal kandidiazis ve %72.7’sinde lingular bulgular saptanmıştır. Astım-Kronik Obstrüktif Akciğer Hastalığı Overlap Sendromu ve Kronik Obstrüktif Akciğer Hastalığı hastalarında lingular bulgular olma oranı daha yüksek iken; bu oran astım hastalarında daha düşüktür. Çalışmaya katılan hasta ve kontrol grubu değerleri karşılaştırıldığında; diş fırçalama sıklıkları, yaş değerleri, gingival ve lingular bulguları arasında istatistiksel olarak anlamlı bir fark vardı (sırasıyla p=0.005; 0.034; 0.001).Sonuç: Çalışmamız, inhaler ilaç kullanımının, oral-orafarengeal, dental yan etkiler açısından, ciddi bir risk faktörü olmadığını göstermiştir. Bu hastaların inhaler ilaç tekniğini doğru uygulayabilme becerileri ve oral hijyenlerine özen göstermeleri sağlanabilirse oral-orafarengeal, dental yan etkileri yaşamayacaklarını düşünüyoruz.
Coherence in Non-technical Summaries of European Central Bank Financial Reports
Authors: Hill-Madsen Aage , Dam-Jensen Helle
Published: April 2022

Positioned on the intersection between the research fields of text linguistics, genre studies and expert-lay communication, this article investigates how and to what extent coherence is achieved in a specific type of summary writing, viz. so-called non-technical summaries (NTS) of financial/economic reports published by the European Central Bank. The investigation is motivated by the observation that while it is incumbent on the writer of any type of document to ensure coherence in his/her product, the special circumstances surrounding summary writing (the fact that summaries are typically required to condense large amounts of information into very limited space) may militate against a sufficient degree of coherence in such texts. Relying to a large extent on the so-called Cohesive Harmony Analysis framework provided by Systemic-Functional Linguistics, the investigation found that while the texts do succeed in employing cohesive devices in such ways and to such an extent that a clear potential for coherence is present, they fail to exploit the potential in a way that makes them properly coherent.
Disputation: Die Macht des Definierens
Authors: Schnedermann Theresa
Published: April 2022

Man findet im Burnout-Diskurs einerseits zahlreiche Passagen in fachinternen/-externen Texten, in denen ein „Noch-nicht-(genug)-Wissen“ oder „unsicheres Wissen“ (Janich 2018: 557) und eine zu wenig trennscharfe, ungenaue Verwendung des Begriffs und das Fehlen einer validen, allgemeingültigen, eindeutigen Definition des Phänomens konstatiert werden. Dieser offensichtlichen Kritik steht allerdings der konvergente Leseeindruck entgegen, der sich in Bezug auf die begriffliche Fassung bzw. Definition von ›Burnout‹ einstellt, wenn man Texte von 1975-2018 zu diesem Phänomen sichtet. Von diesen Beobachtungen ausgehend, analysiert die hier vorgestellte Dissertation: 1.) wie ein psychosomatisches Phänomen, das spezifikationsbedürftig erscheint, in Fach-, Medien- und Vermittlungstexten vor dem Hintergrund fachkultureller, sozialer und diskursiver Bedingungen definiert wird, 2.) wie bestimmte definitorische Merkmale und Definitionsformen sich trotz Kritik über die Zeit im Diskurs durchsetzen und 3.) in welcher Weise sich medizinische/psychologische und fachexterne Ansprüche an die Tätigkeit des Definierens und sprachliche Mittel und diskursive Praktiken des Definierens unterscheiden oder ähneln und sich in Typen diskursiver Praxis des Definierens verdichten lassen.
Prototype Sistem Pendeteksi dan Penetralisir Asap Rokok pada Ruangan dengan Fitur Monitoring Suhu dan Kelembaban
Authors: Utami Firra Azzarah Trie , Kasoep Werman , Novani Nefy Puteri
Published: April 2022

This research was conducted with the aim of detecting and neutralizing cigarette smoke in a room using a messaging application—in this term is Telegram as notification to the user. The system is also equipped with room temperature and humidity monitoring features. In a room that is exposed to cigarette smoke does not have good air circulation, it will cause cigarette smoke not to come out quickly, this problem which will interfere with health, because of the smoke that is inhaled. In this case, we need a system that can detect and neutralize cigarette smoke. For cigarette smoke detection using the MQ-7 sensor, the DC fan and Ozone Generator will automatically turn on if the value on the MQ-7 sensor is greater than or equal to 74 Ppm and the system will also send a notification via Telegram that cigarette smoke is detected. This serves to neutralize air contaminated with cigarette smoke in the room. To monitor room temperature and humidity using the DHT11 sensor and the results of room temperature and humidity monitoring will be displayed on the mobile application.
SISTEM KONTROL DAN MONITORING PH SERTA PEMBERIAN PAKAN IKAN OTOMATIS PADA AQUAPONIK BERBASIS MIKROKONTROLLER
Authors: Dwiky Putra Teguh , Aisuwarya Ratna
Published: April 2022

The research was purposed to create an aquaponic cultivation system that can monitor and control the pH value and provide automatic fish feed based on time scheduling, and detect the amount of fish feed. Then the results of monitoring pH and the amount of fish feed in the feed will be displayed on the smartphone via the Telegram application. The components used in this system consist of NodeMCU, pH-4502C sensor, ultrasonic sensor, DC pump, servo motor, RTC, wiper pump. Aquaponic cultivation systems can be described as a combination of aquaculture (fish farming) and hydroponics (plant/vegetable cultivation without soil media). In addition to fish farming, fish feeding is generally done by humans manually. This has several drawbacks, namely the frequent feeding of fish that is not in accordance with the schedule and the amount of feed given is not measured. As a result of this, it can be in the form of lack of fish nutrition, stunted fish growth, illness, even causing fish death so that fish yields are not optimal. From the research conducted, the results obtained are the percentage of success in the process of monitoring and controlling the pH of the water according to the scheduled time with an accuracy of pH readings of 98.79% and an accuracy of controlling pH of 100%. The percentage accuracy of the amount of feed given is 99.201%. The percentage of accuracy of detecting feed volume is 60.348%.
Human–animal conflicts: socio-philosophical aspects (on the example of the problem of Ophidism).
Authors: Kurbanov Artemiy
Published: April 2022

The subject of the study is the problem of venomous snake bites (ophidism), which is relevant for modern public health and accumulates a range of diverse social practices aimed at preventing or reducing the negative consequences of human contact with a non-human agent (a venomous snake). The problem of ophidism is considered as a special case of conflict between humans and animals, in which a typical scenario of such interactions is embodied, due to the increased anthropogenic impact on nature, which received a powerful impetus during the formation of the colonial system and reached its maximum expression in the XX - early XXI century in the context of the cumulative growth of mankind. The study uses a comprehensive methodology based on a comparative historical approach, comparative analysis of statistical information, socio-philosophical interpretation of the problem of ophidism, considered as a special case of conflict interaction between a person and non-human agents. The approach developed within the framework of Critical Animal Studies (CAS). The study shows the evolution of understanding of the problem of ophidism and its significance in the second half of the XX century - early XXI century, the formation of interdisciplinary optics, which made it possible to interpret a set of particular situations as a single phenomenon due to the specifics of human-nature interaction, taking into account socio-economic factors and as one of the challenges for global health. The conclusion is made about the change in the logic of constructing the agency of the non-human side of the conflict, affecting social activity aimed at preventing it, as well as the possible rejection of the understanding of ophidism as a holistic problem under the influence of other challenges to global health, primarily the COVID-19 pandemic.
The Pap smear in inflammation and repair
Authors: Kamal Meherbano M.
Published: April 2022

Cytology of the uterine cervix is one of the most widely utilized tests and is best known primarily for the cytologic changes seen in precancerous lesions and invasive cancer of the uterine cervix. The more common inflammatory conditions of cervicitis and vaginitis are close clinical differentials, especially when they give rise to excessive blood-stained vaginal discharge. These infective conditions also result in variation in the appearance of otherwise benign squamous and glandular cells in cervical cytology specimens. A variety of physiologic and pathologic conditions are responsible for the conversion of polymicrobial flora of the vagina to a monomicrobial one. The latter may overgrow the others and result in inflammation of the cervix and the vagina. Chronic irritation of the cervix due to intrauterine devices, chemical irritants, inflammation/infection, endocrine changes, and reparative changes can lead to worrisome parakeratosis, hyperkeratosis, and squamous metaplasia of non-keratinized squamous mucosa of the cervix and the vagina and may mimic HPV-related changes. Although some benign changes are specific for certain infections, for example, Trichomonas infestation, most of the reactive and hyperplastic cell morphology are important to recognize only due to the significant morphologic overlap with neoplastic changes in cytology specimens. Identification of different pathogens specifically may not be relevant from a clinical point of view, but is undoubtedly a cytologists’ privilege to inform the clinician! This chapter describes in detail the cytoplasmic and nuclear reactive changes that are found in specific and non-specific inflammatory conditions. In addition, diagnostic pitfalls are emphasized where necessary.
Investigtion and Scientific Explanations of Superstitious Beliefs Held By Senior School Science Students of Oyo State, Nigeria
Authors: AHMED Mulkah Adebisi , Oyedibu Mary Oyepeju
Published: April 2022

This study identified the superstitious beliefs held by the senior school science students of Afijio, Oyo State, Nigeria. Scientific explanations and educational implications of the identified superstitious beliefs were investigated. Purposive random sampling technique was employed to select 300 S.S. 2 students based on socio-economic background. The responses received formed data for the analysis. The Biology-related Superstitious Beliefs Questionnaire (BSBQ) was the instrument. Four research questions were raised and answered while one hypothesis was formulated and tested. The data collected were subjected to frequency count, percentage, ranking and t test. The results indicated that the respondents (i) held some superstitious beliefs about health, pregnancy, food and animals. (ii) A good number of the superstitious beliefs were found to have scientific explanations while some do not have. (iii) Superstitious beliefs affect students in classroom situations (iv) students from poor homes held more superstitious beliefs than those from rich home but there was no statistical difference between them. The recommendation made are that (i) Science educators should relate science more closely to learners, (ii) provide scientific explanations to superstitious beliefs and (iii) Government and non-governmental organizations should support in eradicating superstitious beliefs in our schools irrespective of students socio-economic background.
Türkiye’de Üniversitenin Doğuşu ve Öğretim Üyelerinin Sosyal Profili (1900-1946)
Authors: Demirtaş Aydın
Published: April 2022

1845 yılında kurulması gündeme gelen Darülfünun 1863 yılında halka açık derslerle eğitime başladı. Ancak kalıcı hale gelmesi kolay olmadı ve Darülfünun kurulması üç denemeden sonra 1900 yılında mümkün olabildi. Darülfünunda ilk dersleri verenler Mülkiye, Tıbbiye, Mühendishane gibi modern mekteplerin hocaları ya da yurtiçinde veya yurtdışında modern eğitim süreçlerinden geçmiş devlet erkânıydı. Darülfünunun ilk hocaları mensup oldukları aileler, eğitimleri, doğum yerleri itibariyle bürokratik seçkinlere yakındılar. Büyük çoğunluğu memur ailelere mensuptu ve yurtdışında yükseköğrenim görmüşlerdi. Bazılarının asıl mesleği eğitim dışında bir devlet görevi iken, sadece ders vererek yaşamını sürdürenler ise genellikle Darülfünun yanında dönemin modern okullarında da ders veriyorlardı. Öğretim üyeliğinin standartlarının oturması ve meslekleşmesi 1940’lı yıllara kadar devam etti. Üniversite öğretim üyeliğinin başlı başına bir meslek haline gelmesinden sonra, kültürel ayrım ve yaşam tarzı anlamında çizgiler belirginleşti ve bağımsızlaşma süreci başladı. Belli bir tarihten sonra doktorası olmayanların, bürokratlar ve vekillerin ders vermesinin önü de yasalarla kesildi. Akademik ünvanlar, sürekli kadrolar, uzmanlıklar, normlar ve sınırları çizilmiş rollerle üniversite hocalığı profesyonel bir meslek haline geldi. Bu makalede 1900-1946 yılları arasında öğretim üyesinin nasıl doğduğunu, nasıl bir profil sergilediğini ve toplumda nasıl konumlandığını ortaya koymaya çalıştık. Belirtilen tarih aralığında görev yapmış öğretim üyelerinin profiline dair çıkarımlar arşiv kayıtları, biyografi ve otobiyografi taramalarına dayanmaktadır.
Sosyolojik Bir Bağlam Olarak Ailede Bireyin Özneleşme Deneyimi
Authors: Yazar Ayşegül
Published: April 2022

Özneleşme kavramı, birey-toplum ikiliğini anlamamızda anahtar rol oynayan bir kavram olarak karşımıza çıkmaktadır. Ancak bunun, çoğu düşünür tarafından farklı şekillerde tanımlanması ve bu tanımların kuramsal düzeyde sınırlı kalması, zaman zaman kavramın muğlaklığına neden olmakta ve birey-toplum ikiliğinin anlaşılmasını güçleştirmektedir. Çalışmanın amacı bu muğlaklığı ortadan kaldırmaktır. O nedenle özneleşme kavramı, bir sosyal bağlam içinde değerlendirilecek, etkileşimler ve sosyal ilişkiler ağı içinde ele alınacaktır. İki bölüme ayrılan çalışmanın ilk kısmında özneleşme kavramının tarihsel süreç içerisindeki farklı tanımlarına, ikinci bölümde ise bu kavramın, nitel verilerin analizi yöntemi ile aile bağlamında bireyi nasıl şekillendirdiğine yer verilecektir. Özetle, özneleşme kavramının süreç içinde değişime uğrayan dinamik bir özelliğe sahip olduğu ve birey-toplum ikiliğini anlayabilmek için bu kavramın gerçek bir sosyal ilişkiler ağı içerisinde incelenmesi gerektiği sonucuna ulaşılmıştır.
Kitap Değerlendirmesi Poetik ve Politik: Bir Kültürel Çalışmalar Ansiklopedisi
Authors: Tzampaz Salich
Published: April 2022

Dellaloğlu’nun hangi eserini okursak okuyalım, hepsinin birbiriyle bir ilişki içerisinde olduğunu görüyoruz. Dolayısıyla, yazarın eserlerini tek bir ontoloji etrafında şekillenmiş eserler olmakla birlikte bu eserlerin temelini Frankfurt Okulu’nda Sanat ve Toplum (2007) adıyla yayınlanan Yüksek Lisans tezi oluşturuyor. İncelediğimiz eser olan Poetik ve Politik: Bir Kültürel Çalışmalar Ansiklopedisi (2020) ise olgunlaşmış fikirlerin okura sunulmuş hali gibidir. Bu eseriyle -fazla abartılı gelmeyecekse- yazarın kendisine ait bir ‘Dellaloğlu sözlüğü’nü veya ‘Dellaloğlu okuma kılavuzu’nu yazdığını söyleyebiliriz.
Effect of Various Pranayama Practices in Competitive Swimmers: A Review
Authors:   Post Graduate Scholar, Department of Swasthavritta (Social and Preventive Medicine), Amrita school of Ayurveda, Amritapuri, Amrita Viswavidyapeetam, Kollam, Kerala, India, S Haripriya , DT Robin ,   Associate Professor, Department of Swasthavritta (Social and Preventive Medicine), Amrita school of Ayurveda, Amritapuri, Amrita Viswavidyapeetam, Kollam, Kerala, India, A Dileep ,   Associate Professor, Department of Swasthavritta (Social and Preventive Medicine), Amrita school of Ayurveda, Amritapuri, Amrita Viswavidyapeetam, Kollam, Kerala, India, S Meera ,   Associate Professor, Department of Swasthavritta (Social and Preventive Medicine), Amrita school of Ayurveda, Amritapuri, Amrita Viswavidyapeetam, Kollam, Kerala, India, M Vandana Rani ,   Professor and Head, Department of Swasthavritta (Social and Preventive Medicine), Amrita school of Ayurveda, Amritapuri, Amrita Viswavidyapeetam, Kollam, Kerala, India
Published: April 2022

Pranayama (yogic breathing) an essential component of Yoga, is said to influence both physiological and psychological aspects of humans. But its effectiveness in the field of sports especially in swimmers are less explored. The online databases were searched for the citations with “Pranayama, Yogic Breathing, competitive swimmers, competitive swimming, nadishudi pranayama, bhastrika pranayama, ujjayi pranayama, Bhramari Pranayama and Kapalabhathi” as keywords from the date of inception of the databases till October 2020. Experimental papers in English, revealing the effects of yogic breathing in competitive swimmers, effects of yogic breathing in lung capacity, lung function and psychological system and also papers showing the effect of pranayama on metabolic pathway were included in the review. The studies that had used yogic breathing in combination with other Yoga practices, studies in languages other than English, and whose abstracts were unavailable were excluded from the review. From the data gathered it was evident that pranayama has positive health effect and performance enhancement in competitive swimmers. Regular practice provides physiological and psychological wellbeing. Pranayama or yogic breathing act as a physiological stimulation. It has a multi-systemic effect in the human body. The rhythmic, slow and forceful inspiration and expiration in pranayama strengthen respiratory muscles, improve the expiratory power, and decrease resistance to the airflow in the lungs and increase voluntary breath holding time. Moreover, it brings sympathetic and parasympathetic nervous system into balance. This paper intends to explore the effect of a set of pranayama practice in competitive swimmers.
Effects of Whole Body Vibration on Processing Speed in Stroke Patients - A Pilot Study
Authors:   Sports Sciences Institute, Saarland University, Saarbrücken, Germany, A Dincher , G Wydra ,   Sports Sciences Institute, Saarland University, Saarbrücken, Germany
Published: April 2022

Background: The motor consequences of a stroke are mainly treated with physiotherapy and blood thinning drugs. In exercise therapy with whole body vibration, studies with other patient groups show positive effects already after a single application. In stroke patients the effectiveness of whole body vibration is still quite inconsistent. Therefore, the present study aims to investigate the effectiveness of whole body vibration on processing speed in stroke patients. Hypothesis: Whole body vibration has a positive effect on processing speed in stroke patients. Methods: 13 stroke patients (age 68.23 ± 8.93 years, mean time past since stroke 10.82 ± 8.83 months) were randomized in two groups subjected to whole body vibration at 6 and 12 Hz, respectively. Before and after the treatment of 5 x 60 seconds with a break of 60 seconds between each set, the Digit Symbol Test was performed. Results: Both groups improved their performance significantly from pre- to posttest (F(1,11) = 15.85; p = 0.002). There is no difference between groups and no interaction effect for factor time*group. Conclusions: Even lower application frequencies (6 and 12 Hz) can have a positive effect on the processing speed of stroke patients. Nevertheless, further studies must try to develop an optimal training protocol for this patient group.
Factors associated with the degree of 99mTc-MIBI accumulation in parathyroid glands neoplasms during planar scintigraphy and SPECT/CT in primary hyperparathyroidism
Authors: Slashchuk Konstantin Y. , Degtyarev Mikhail V. , Rumyantsev Pavel O. , Rebrova Olga Y. , Elfimova Alina R. , Selivanova Liliya S. , Mokrysheva Nataliya G.
Published: April 2022

Background: Primary hyperparathyroidism (PHPT) is the third most common endocrine disease, after diabetes mellitus and thyroid gland disorders. Surgical removal of the hyperfunctioning parathyroid glands is the only radical treatment. Various methods of preoperative imaging and intraoperative navigation are developed. Planar scintigraphy with 99mTc-MIBI is used for visualization and it is the most frequently performed radionuclide study in PHPT, while it has a relatively low sensitivity and specificity. SPECT/CT can reduce false-negative and false-positive results, and combines the advantages of radionuclide diagnostic methods and computed tomography. However, the factors that prevent the accumulation of 99mTc-MIBI in patients with PHPT are not clear enough.
Aim: To identify the factors associated with the degree of accumulation (uptake rate) of 99mTc-MIBI in the parathyroid glands during planar scintigraphy and SPECT/CT.
Materials and methods: The cross-sectional comparative study included 186 patients with PHPT who underwent planar scintigraphy and SPECT/CT for topical diagnosis of parathyroid glands and minimally invasive parathyroidectomy (MIP) followed by histological and immunohistochemical examination of parathyroid glands. The patients were divided into 3 groups depending on the accumulation of 99mTc-MIBI. The accumulation of 99mTc-MIBI was assessed by the expert as low-, moderate-, and high-intensity.
Results: The association between the volume of the parathyroid glands on ultrasound and the intensity of the capture of the radiopharmaceutical was revealed, and 80% of low uptake is observed if volume is less than 0,215 cm3 (it corresponds to the linear size of the parathyroid gland 5 mm). Next factor that complicate the interpretation of the results of planar scintigraphy and SPECT/CT in patients with PHPT is thyroid diseases. The associations of the level of PTH, calcium in the blood, the localization and cellular composition of the parathyroid glands, the index of proliferative activity (Ki67), the expression of PTH, P-glycoprotein, cyclin D1 in the PTG tissue with the intensity of 99mTc-MIBI accumulation were not found.
Conclusions: The main factor that positively associates with the degree of 99mTc-MIBI accumulation with planar scintigraphy and SPECT / CT is the volume of the parathyroid glands according to ultrasound data. Comorbidity of the thyroid gland has tendency to be associated with a negative result of radionuclide diagnostics, thus based on the ultrasound data of the thyroid and parathyroid glands it is possible to choose the second preferable method of imaging (SPECT/CT or contrast enhanced CT).
The biobank of the National Medical Research Centre for Oncology as a resource for research in the field of personalized medicine: A review
Authors: Kit Oleg I. , Timofeeva Sofia V. , Sitkovskaya Anastasia O. , Novikova Inna A. , Kolesnikov Evgeniy N.
Published: April 2022

Biobanks are the platform for innovative biomedical research in the field of translational and personalized medicine. The important aspect for conducting large-scale research in the field of genomics, transcriptomics, proteomics is the availability of a sample information of the documented high-resolution samples. The biobanks solve the problem of forming groups of patients with different nosology within the population of interest and provide clinical and laboratory information on each sample. The aim of this article is to describe the Biobank processes of the National Medical Research Centre for Oncology within the framework of existing projects and build up collections. The review discusses the main stages of the systematized biobank process, describes the methods of sample preparation of different types of biological material, and also provides statistics of the build up collections. To this date, the predominant part of the depository consists of tissue samples of patients diagnosed with colorectal cancer 24% and stomach cancer 23% of the total number of tissue samples, while the number of tissue samples of pancreatic cancer is 10%, and esophageal cancer and breast cancer 22%. In addition to tissue samples, the biobank of the National Medical Research Centre for Oncology stores 24 cell lines of a human origin and the collection of 200 microbiota samples: 100 are from patients diagnosed with lung cancer and 100 from conditional healthy donors. Currently, the studies have been performed on biomaterial from the biobank build up collections to search for prognostic biomarkers and potential targets for targeted therapy by using high-throughput sequencing in patients diagnosed with pancreatic cancer and brain cancer. Thus, the collections play an important role for research in the field of personalized medicine, providing early diagnosis and effective treatment for each patient.
Therapy of lymphoproliferative diseases in the era of COVID-19: challenges and solutions
Authors: Poddubnaya Irina V.
Published: April 2022

On January 20,2022, the symposium "Therapy of lymphoproliferative diseases in the era of COVID-19: difficulties and solutions" was held. It was organized by the Russian Society of Oncohematologists. At the symposium, the experience of the hematology service of City Clinical Hospital №52 of Moscow was discussed, as well as changes in international clinical guidelines for managing patients in conditions of COVID-19 based on a review conducted by the European Hematology Association (EPICOVIDEHA).
Indonesian freshwater fisheries’ oil for health and nutrition applications: a
narrative review
Authors: Sasongko H. , Nurrochmad A. , Nugroho A.E. , Rohman A.
Published: April 2022

The consumption and production of freshwater fish in Indonesia have recently increased
significantly, especially in the food sector. This is for health purposes due to the dietary
content, including freshwater fish protein. Fish is not only a source of protein but also a
considerable supply of polyunsaturated fatty acids (PUFAs) and is essential. Using fish
oils has caught a growing interest due to an increased understanding of the possible health
benefits of omega-3 fatty acids in humans. This review provided thoughts on progress in
the research of Indonesia’s freshwater fisheries’ oil potential. Here, fish oil's potential was
addressed through its outstanding biochemical features and its potential as an antiinflammatory, cardiovascular, cancer, and autoimmune disorder agent. Generally,
nutritional properties, their possible application in food production, and therapeutic and
socioeconomic significance are considered. Indonesian freshwater aquaculture fisheries
and inland capture fisheries have the potential for refined fish oil production. The top
freshwater fisheries include aquaculture (Oreochromis niloticus, Clarias, Cyprinus carpio,
Pangasius, and Osphronemus goramy) and inland capture fisheries (Channa striata,
Oreochromis niloticus, Trichogaster, Hemibagrus capitulum, and Pangasius). Indonesian
fish oil is rich in omega-3 fatty acids, especially eicosapentaenoic acid and
docosahexaenoic acid, and can potentially be developed into drugs and food supplements