bluuebunny/crossref_metadata_2025 huggingface dataset:
Knowledge Mapping and Global Trends in the Field of the Objective Structured Clinical Examination: Bibliometric and Visual Analysis (2004-2023)
Authors: Ba Hongjun , Zhang Lili , He Xiufang , Li Shujuan
Published: September 2024

Background

The Objective Structured Clinical Examination (OSCE) is a pivotal tool for assessing health care professionals and plays an integral role in medical education.

Objective

This study aims to map the bibliometric landscape of OSCE research, highlighting trends and key influencers.

Methods

A comprehensive literature search was conducted for materials related to OSCE from January 2004 to December 2023, using the Web of Science Core Collection database. Bibliometric analysis and visualization were performed with VOSviewer and CiteSpace software tools.

Results

Our analysis indicates a consistent increase in OSCE-related publications over the study period, with a notable surge after 2019, culminating in a peak of activity in 2021. The United States emerged as a significant contributor, responsible for 30.86% (1626/5268) of total publications and amassing 44,051 citations. Coauthorship network analysis highlighted robust collaborations, particularly between the United States and the United Kingdom. Leading journals in this domain—BMC Medical Education, Medical Education, Academic Medicine, and Medical Teacher—featured the highest volume of papers, while The Lancet garnered substantial citations, reflecting its high impact factor (to be verified for accuracy). Prominent authors in the field include Sondra Zabar, Debra Pugh, Timothy J Wood, and Susan Humphrey-Murto, with Ronaldo M Harden, Brian D Hodges, and George E Miller being the most cited. The analysis of key research terms revealed a focus on “education,” “performance,” “competence,” and “skills,” indicating these are central themes in OSCE research.

Conclusions

The study underscores a dynamic expansion in OSCE research and international collaboration, spotlighting influential countries, institutions, authors, and journals. These elements are instrumental in steering the evolution of medical education assessment practices and suggest a trajectory for future research endeavors. Future work should consider the implications of these findings for medical education and the potential areas for further investigation, particularly in underrepresented regions or emerging competencies in health care training.
Validation of An HPLC Method for the Determination of Some Β-Lactams Antibiotics Using A Green Analytical Technique
Authors: Nguyen Thoai Dang , Phuong Anh Tran Thi Phuong , Truong Quoc Ky
Published: September 2024

Green analytical chemistry (GAC) primary goal is to develop environmental and health-friendly analytical methods by reduction or replacement of hazardous substances from analytical procedures. In this research, the application of GAC to quantify five β-lactams antibiotics (cefuroxime sodium, cefaclor, ertapenem sodium, ampicillin sodium and sulbactam sodium) by high-performance liquid chromatography (HPLC) using photodiode arrays (PDA) detector was developed. To achieve this, ethanol was used as a green replacement for methanol and acetonitrile, common solvents in chromatographic procedures. Several chromatographic conditions were investigated to accomplish the optimal conditions. The method validation followed the ICH Q2 (R1) guideline, and the developed method was successfully applied for quantifying some pharmaceutical products.
Optimizing the Formula of Polymeric-Based Aripiprazole Nanosuspension Using Response Surface Methodology for Intranasal Drug Delivery
Authors: Aisiah Nabila Fatin , Surini Silvia
Published: September 2024

This study aimed to optimize the formula of aripiprazole nanosuspension for intranasal drug delivery. Response Surface Methodology (RSM) was employed to determine the influence of independent variables, including drug concentration, polymer concentration, and the ratio of polymer combination, on the nanosuspension characteristics. The parameters under investigation were particle size (d mean), polydispersity index, and drug content. Fifteen formulas were prepared using the high-shear homogenization–ultrasonication method, and the Design Expert software was applied for optimum formula determination. The result showed significant effects of the independent variables on the nanosuspension characteristics, with particle sizes ranging from 143.6 – 334.6 nm, PDI values of 0.302 – 0.649, and drug content was 98.7 – 102.1 %. The predicted optimum formula had a drug concentration of 28 mg/mL in the organic solvent, polymer concentration of 1.5% (w/v), and HPMC to PVP ratio of 1.4 with desirability of 0.94. Additionally, it exhibited desirable characteristics, such as a particle size of 171.2  11.4 nm, a PDI value of 0.317  0.02, and a high drug content of 100.04  0.65%. In conclusion, the presented methodology appeared to be perfect for the optimization of the aripiprazole nanosuspension formula to ensure suitability for nose-to-brain drug delivery.
PyPLIF HIPPOS-aided Construction and Retrospective Validation of Structure-Based Virtual Screening Protocol Targeting VEGFR2
Authors: Supanji Supanji , Perdamaian Ayudha Bahana , Marsifah Titi , Istighfari Jenie Riris , Ikawati Muthi , Kartikawati Paramita Dewi , Perdana Istyastono Enade
Published: September 2024

Recently, the discovery of small molecules as inhibitors for vascular endothelial growth factor receptor 2 (VEGFR2) is of timely interest, especially in the area of ocular neovascular diseases. On the other hand, PyPLIF HIPPOS in combination with machine learning techniques has been reported to increase the prediction quality of structure-based virtual screening (SBVS) protocols. The original version of PyPLIF has served in the development of an SBVS protocol that successfully identified novel chalcone derivatives and short peptides as potent inhibitors for acetylcholinesterase. In this short communication, construction and retrospective validation of an SBVS protocol employing PyPLIF HIPPOS targeting VEGFR2 are presented to make it publicly available. The retrospective validation employed 409 active compounds and 24,950 decoys from the enhanced version of the directory of useful decoys. All compounds were docked independently 3 times using AutoDock Vina followed by the identification of the protein-ligand interaction fingerprints (PLIF) employing PyPLIF HIPPOS. The derived ensemble PLIF descriptors were then used in the decision tree construction using a machine-learning technique called recursive partitioning and regression trees. The best decision was then incorporated in the SBVS protocol. The F-measure and enrichment factor values of the SBVS protocol were 0.387 and 76.879, respectively. Hence, the SBVS protocol is readily available to screen small molecules or short peptides.
Building an Age-friendly Digital Service System for Chinese University Libraries
Authors: Gao Kaixuan , Xiao Siyi , Tang Bin
Published: September 2024

As the aging process accelerates and information technology rapidly advances, the differences between the elderly and the digital society are becoming more pronounced. This highlights the need to bridge the digital divide and improve the quality of life for older people. University libraries play an important role in this. This study builds on the successful implementation of the Joint Information Systems Committee (JISC) digital capabilities framework in the United Kingdom (UK) to inform the design of digital services for Chinese University libraries. To improve these outcomes, university libraries need to prioritize three key areas: establishing a comprehensive strategic plan, developing a collaborative learning ecosystem, and innovative digital tools stirring together. Subsequent research will examine the efficacy of this system in a variety of settings and explore strategies for optimizing its visibility and effectiveness.
Study of College English Teachers’ Instructional Design Competence— Case Study of Teaching Methods
Authors: Sun Jianmei
Published: September 2024

Teaching competence is very important for a teacher, and it is a basic skill of every teacher. However, there are few researches on Chinese University Teachers' instructional design competence, especially from the perspective of teaching methods. In order to investigate the teaching design competence of College English teachers, this study adopts the method of case analysis. The winning works of "Shanghai Foreign Language Education Press Cup" National English teaching competition were selected as the cases. Data analysis was made by using tables to list related evaluations. Data analysis shows that most participants can choose the appropriate teaching methods according to the teaching objectives, but only a few participants can choose innovative teaching methods. It is necessary to design teaching method according to teaching content. Some teachers cannot design teaching methods reasonably, which shows that teachers' ability to match teaching content and teaching methods needs to be improved. Teaching methods should be able to promote the realization of teaching objectives. However, the research shows that the teaching methods selected by some participants cannot help promote the realization of teaching objectives. The research shows that the overall teaching design literacy of university teachers needs to be improved. If we want to get a more accurate survey of the status quo, we should also have a deeper understanding about the instructional competence of teachers.
Haga su diagnóstico
Authors: Córdova Galván Daniel E. , López Lauze Anaïs , Lanzarin Minero Abel Manuel , Ayala González Cosi Paulina , Becker Mayorga Joshua , Ruiz Barrenechea Regina
Published: September 2024

In the present case offered by Dr. Ramírez-Arias' team, a colon study by enema was carried out as request of the family doctor. It is a radiological study using a radiopaque contrast medium enema; that by firing the X-ray, it is possible to observe and highlight the structure of the inner wall or mucosal lining of the colon. So it is possible to detect diseases and abnormalities. We invite you to carry out this exercise that involves a currently asymptomatic geriatric patient who was diagnosed in a timely manner using radiological tools.
The RAS Paradigm in Mainframe Systems: A Comprehensive Analysis of Design Principles and Operational Benefits
Authors: Raju Jagadish
Published: September 2024

This article examines the critical role of Reliability, Availability, and Serviceability (RAS) in mainframe computing systems. We explore how RAS principles have become fundamental design features in modern mainframes, enhancing their ability to meet the demanding requirements of enterprise-level data processing. The article provides an in-depth analysis of each RAS component, detailing how reliability is achieved through robust hardware self-checking and extensive software testing, availability is maintained via seamless component failover and layered error recovery, and serviceability is ensured through advanced diagnostic capabilities and modular replacement units. We argue that the holistic integration of RAS principles in mainframe architecture not only maximizes system uptime and operational continuity but also significantly impacts application design and overall system efficiency. Through a comprehensive review of current mainframe technologies and industry practices, this article highlights the enduring importance of RAS in an era of increasing computational complexity and datadriven decision making. Our findings suggest that RAS principles will continue to evolve, playing a crucial role in shaping the future of high-performance, mission-critical computing systems.
Extraction of Bacterial Pigments and Evaluation of its Antioxidant Activity
Authors: Chudiwal Dr. Anupriya
Published: September 2024

Carotenoid are pigment that exist in a wide variety of plant and microorganism they are characterized by red, yellow or orange coloration .These important pigment play significant role in animal and human health .In contrast to plant production, the advantages of microbial fermentation of carotenoids were lower media cost, fast growth rate of microorganism and the ease of culture control . When the microbial cells are used to produce the color the term refers to ‘microbial pigments’. Different types of pigments extracted from different microbes. In this study, soil and water samples were collected from different areas of MGM University, Chh. Sambhajinagar .Different pigmented colonies were observed on nutrient agar plate .Out of these, the orange and yellow colonies were selected and sub-cultured further to obtain their pure cultures. These samples were inoculated onto nutrient agar plates, and after an incubation period of 24 hours, different colonies were observed on the plates. Out of these, the orange and yellow isolated were selected and sub-cultured further to obtain their pure cultures. After production of the pigment in liquid medium, it was further processed for the extraction of these pigments. Further, antioxidant assay by radical scavenging activity of DPPH was carried out, which revealed that the pigment had an radical scavenging activity of 60% as compared to that of the standard ascorbic acid, which showed radical scavenging activity of 33 %. Thus, the current study can be a useful step for large-scale production of pigments, their purification and application in cosmetic industries
Designing Microstrip Low-Pass Filter with Cutoff Frequency 3GHz
Authors: Mohamed Abobkr H. R. , Abobker Saleman A. A
Published: September 2024

Abstract: The aliasing phenomenon became a problem in communication systems when an input signal includes high frequency components. These higher frequencies can fold on the lower frequency spectrum and appear as erroneous signals that cannot be distinguished from valid sampled data. Therefore, will design low-pass filter with cut-off frequency 3GHz using Microstrip technique which will work to remove and reject these high frequencies, in addition to microstrip technique, would be design lowpass filter using lumped elements to make comparison between them. There are two methods which can used to design Microwave Filters, the first method is Image parameters and the second is Insertion Loss method. These methods will explain. RF and microwave filters may be designed as lumped element or distributed element circuits; they may be realized in various transmission line structures, such as waveguide, coaxial line, and microstrip. In practice, high-performance microwave filters with minimized size and weight are playing an important role for design and fabrication of high-efficiency miniaturized microwave systems. Software simulation is done by using Microwave Office V.6.4 software, Graphs, and Electronics circuits will be presented
Impact of Parent Interest in Mathematics and Students Mathematics Interest on Student Mathematics Achievement
Authors: Boateng Francis Ohene , Bandoh Sampson Owusu , Kwarteng Sarah , Lotey Ebenezer Kwesi
Published: September 2024

A student's academic and cognitive development is greatly influenced by their mathematics education, and the importance of parental participation in promoting this interest cannot be estimated. The study aims to evaluate the impact of parental interest in mathematics and student’s mathematics interest on students’ mathematics achievement. The study employed quantitative research method with the used of structured questionnaire for collecting data. The sample of the study comprised of 200 first-year students from four selected senior high school in Ghana-Kumasi. The study findings revealed that, parent interest and student interest in mathematics had a statistically significant direct positive impact on students’ mathematics achievement. Moreover, there relationship between parental interest and students’ interest in mathematics had a positive effect and was statistically significant.
O uso de Ferramentas da Qualidade por lideranças de enfermagem em uma grande instituição hospitalar brasileira
Authors: Pereira Santos Jadson Nilo , Gonçalves Flávia Maria , Rocha Ronalty
Published: September 2024

O objetivo dessa pesquisa foi identificar o entendimento de lideranças de enfermagem acerca do uso das ferramentas da qualidade para o gerenciamento do cuidado. Trata-se de estudo com uma abordagem quantitativa e qualitativa, caracterizada como uma investigação exploratória e descritiva realizada em um hospital de grande porte, localizado no município de São Paulo. A coleta de dados foi realizada no segundo semestre de 2023. Concluiu-se que as lideranças de enfermagem compreendem as ferramentas da qualidade como mecanismos de melhoria no processo de cuidar dos pacientes e permitirem identificar as fragilidades e potencialidades de cada unidade de trabalho assistencial. Além disso, essas ferramentas auxiliam no processo de melhoria contínua, tomada de decisão e definição de outros métodos gerenciais a partir do diagnóstico oferecido pelas ferramentas utilizadas.
Production and logistics 4.0 in the food industry in the Czech Republic
Authors: Heinzova Romana , Strohmandl Jan , Janova Nikola
Published: September 2024

The food industry is the most important sector of the national economy of the Czech Republic, which significantly contributes to the fulfillment of fundamental macroeconomic aggregates such as gross domestic product, employment, exports and others. The food industry is currently facing pressure from customers for higher quality and safety while maintaining low prices. At the same time, however, they must ensure high safety and productivity of their production and logistics flows when there is a shortage of manpower. Another aspect is the sustainability of logistics and supply chains, i.e. the requirement for new materials, packaging and technologies enabling maximum processing and use of inputs. From this point of view, the application of Industry 4.0 elements to the food industry appears to be a necessary step for the company's competitiveness. The article summarizes the results of a questionnaire survey that took place in the period April-May 2023 through the Internet tool Survio. A structured questionnaire was sent to 206 food businesses in the Czech Republic. The enterprises were selected according to the database of the Ministry of Agriculture. 69 enterprises returned correctly completed questionnaires, which makes the return rate 33%. Questions were directed to the area of process stability as a result of two crises, the Russian-Ukrainian crisis and the Covid-19 pandemic. Further to the field of automation, digitization and robotization to evaluate the current state of involvement of food production in Industry 4.0.
Prototype design and analysis of a mobile robot
Authors: Viet Dang
Published: September 2024

Mobile robots are robots that can move on their own. Robots move in their environment, not fixed to a real location. With the flexibility of the navigation wheel combined with the dynamic system, the wheeled mobile robot is suitable for flexible movement on flat terrain, using tank-like tracks will be suitable for moving on difficult, complex, bumpy terrain. The article introduces a process of developing, designing a mobile robot combining a 4-degree-of-freedom arm with a mobile chassis. Kinematics, dynamics, strength of structure testing and simulation are all calculated in detail. Finally, a prototype was built and tested to prove the correctness of the process. The project has calculated the kinematics and dynamics of the model, thereby building trajectories, designing controllers for the vehicle and manipulator, thereby simulating problems on Matlab-Simulink. Designing 3D CAD models, building hardware, and testing CAE durability on Abaqus software. The results are visually tested by software, with high feasibility, is the premise for manufacturing.
HUTAN LINDUNG TAMAN NASIONAL KERINCI SEBLAT: BAGAIMANA KEBIJAKAN PEMERINTAN DALAM MENJAGA KELESTARIANNYA?
Authors: Anugerah Bayu , Buana Sandyka , Helmi Helmi
Published: September 2024

artikel ini menganalisis bentuk kebijakan Pemerintah dalam menjaga kelestarian hutan lindung Taman Nasional Kerinci Seblat di Kabupaten Musi Rawas Utara. Metode penelitian yang penulis terapkan dalam penulisan ini yaitu dengan metode penelitian yuridis empiris dengan menggunakan pendekatan kualitatif, penarikan sampel dilakukan dengan cara proposive sample. Dalam pembahasan, ditemukan bahwa secara formal Pemerintah Kabupaten Musi Rawas Utara tidak mengeluarkan kebijakan yang langsung mengatur tentang Hutan Lindung TNKS, tetapi ada beberpa kebijakan yang dikeluarkan oleh Pemerintah Provinsi Sumatera Selatan melalui Peraturan Daerah, Peraturan Kepala Daerah, Surat Keputusan Kepala Daerah, MoU/Nota Kesepahaman dan Efektivitas kebijakan pemerintah dalam menjaga kelestarian Hutan Lindung Taman Nasional Kerinci Seblat di Kabupaten Musi Rawas Utara sudah cukup baik, tetapi dalam pelaksanaannya masih kurang efektif. Selain itu, efektivitas kebijakan pemerintah tentang TNKS dapat juga dilihat dari kerusakan hutan lindung TNKS yang mengalami kerusakan yang disebabkan oleh kasus perambahan hutan, pencurian kayu/illegal logging, dan pertambangan emas tanpa izin (PETI). Sebagai saran atas kesimpulan tersebut disarankansepatutnya kita turut serta dalam menjaga dan melindungi hutan, tidak hanya Hutan Lindung TNKS karena hutan mempunyai peran dan fungsi yang sangat penting bagi kehidupan kita semua dan bagi Pemerintah Provinsi Sumatera Selatan maupun Pemerintah Kabupaten Musi Rawas Utara seharusnya dapat membuat kebijakan yang lebih efektif untuk menjaga kelestarian Hutan Lindung TNKS, dan untuk Instansi terkait perlu melakukan sosialisasi kepada masyarakat.
Kebijakan Pemerintah dalam Menetapkan Upah Minimum yang Layak di Era Revolusi Industri 4.0
Authors: Tjakradirana Erri , Rosida Nina , Wijaya Endra
Published: September 2024

Kajian ini membahas mengenai kebijakan pemerintah mengenai penetapan upah minimum yang dihubungkan dengan kondisi era Revolusi Industri 4.0. Revolusi Industri 4.0 sarat dengan penggunaan teknologi informasi yang canggih. Apakah kondisi tersebut sudah ikut dipertimbangkan dalam kebijakan penetapan upah minimum? Kajian ini menggunakan metode penelitian yuridis normatif dengan analisis data secara kualitatif. Kajian ini menyimpulkan bahwa selama ini, kebijakan pengupahan belum secara maksimal ikut mempertimbangkan atau merespons kebutuhan era Revolusi Industri 4.0 yang dihadapi oleh buruh. Secara potensial, aspek pendidikan sebenarnya bisa menjadi faktor penting bagi buruh untuk dapat beradaptasi di tengah-tengah situasi era Revolusi Industri 4.0. Upaya untuk meningkatkan besaran penghitungan unsur pendidikan bagi buruh sebagai bagian dari komponen upah minimum lantas menjadi mendesak untuk direalisasikan.
Alberto Moravia in the USSR (Documents from Russian State Archive of Literature and Art)
Authors:   А.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Golubtsova Anastasia V.
Published: September 2024

This publication presents some documents from the Russian State Archive of Literature and Art (RGALI) regarding two trips to the USSR made by Alberto Moravia, one of thegreatest Italian writers of the 20th century, and his relationship with Georgij Breitburd, translator andconsultant on Italian literature at the Foreign Commission of the Union of Soviet Writers, one of thecrucial figures in Soviet-Italian cultural relations. Moravia, as an influential left-wing intellectual, was widely known and frequently published in the Soviet Union and was considered one of the “friends” of the USSR. The documents presented here are related to two of Moravia’s trips to the USSR in 1956 and 1972. These are reports on both trips written by Breitburd, who accompanied Moravia as an interpreter; a stenographic transcript of a lecture on contemporary Italian literature given by Moravia at Maxim Gorky Literature Institute in Moscow; and Moravia’s correspondence with Mikhail Apletin and Georgij Breitburd after the trip of 1956. These documents give us valuable information about the programs of Moravia’s visits and the issues discussed at formal events and informal meetings. They also tell us a lot about Soviet “hospitality techniques” and demonstrate how the work with Western intellectuals was organized. The documents published here are accompanied by a detailed commentary and an introduction, briefly summarizing the history of relations between Alberto Moravia and the USSR.
One Torn Letter by Anna Akhmatova
Authors:   Institute of Russian Literature (Pushkin House) of the Russian Academy of Sciences, Rubinchik Olga E.
Published: September 2024

For the first time, this article presents a torn and discarded letter by Anna Akhmatova, which was glued and preserved by Pavel Luknitsky. Part of the letter and the appeal to the addressee are lost, so in the archive (Institute of Russian Literature of the Russian Academy of Sciences) the document is listed as a letter to an unidentified person. The publisher determines the addressee and date according to the content and presumably restores some lost words. Attribution and restoration of gaps are accompanied by a detailed justification. The letter, written on March 27, 1925, was addressed to Akhmatova’s mother, Inna Erasmovna Gorenko, who at that time lived with her sister Anna Erasmovna Vakar and her family in severe poverty in the former Vakar estate in Podolsk province (now Khmelnitsky region of Ukraine). The article describes the main characters in the letter and the difficult circumstances of Akhmatova’s life at this time, which are half-hidden behind a few lines of text. The article also provides comments on the names mentioned in the letter. It reveals the relationship between Akhmatova and the poet Maria Shkapskaya; it tells us about a little-known friend of Akhmatova to whom she dedicated her poem, “If the moon’s horror is splashing...” (1928), — about Mikhail Zimmerman, assistant director-administrator at the former Mariinsky Theatre. A study of his file in the fund of the Directorate of Academic Theatres (Central State Archive of Literature and Art) reveals several facts about his biography.
Shmelev in the USSR. (Chapter Two: Editions and Reception in Post-War Period)
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Nikolaev Dmitry D.
Published: September 2024

The article examines the history of the publication and reception of I.S. Shmelev’s works in the USSR from the point of view of his emigrant status after the Great Patriotic War. In the after-war decade, Shmelev practically disappeared not only from the readers’ but also from the research area. He is not considered a figure of sufficient significance in the literary process, even in the fundamental academic “History of Russian Literature.” Only in 1957, Shmelev’s first book with a preface by B.V. Mikhailovsky was published in the USSR after a long break, and then two more collections prepared by O.N. Mikhailov (in 1960 and 1966), which gradually filled in the gaps in educational and academic works. Shmelev’s works entered the scholarly interpretation of the literary process as full-fledged components only in the 1970s, but this applies only to the pre-revolutionary period. The complete description of the emigrant period is still a few pages in the preface by O.N. Mikhailov (1966). In 1957–1966, Shmelev was published but practically not studied, and in the 1970s and early 1980s, Shmelev was studied but not published. Only since 1988 Shmelev’s books begin to be published in the USSR one after another. A new stage of his “presence” in his homeland begins, during which his emigre works first rose to the level of pre-revolutionary works and then came forward.
Novel Onset of Cutaneous Lupus Erythematosus Induced by Pembrolizumab
Authors: Pogorelov Dimitrii , Strotkötter Heribert , Bjelic-Radisic Vesna , Wesselmann Ulrich , Hübinger Jonas , Sabulyte Simona , Hofmann Silke C. , Balakirski Galina
Published: September 2024

Abstract is missing (Short Communication)
Evaluation of Serum Interleukin 35 and Interleukin 38 and Electrolyte Level in the Sera of Rheumatoid Arthritis and Osteoarthritis Iraqi Females
Authors: Mahdi Montadher Ali , Mohammed Mustafa Taha , Klichkhanov Nisred K.
Published: September 2024

Background: Rheumatoid arthritis (RA), is a disease that happened because autoimmune and inflammatory effects, it is mean that the human immune system offence healthy cells in the body mistakenly, resulting in inflammation (swelling) in the impacted portions of the body. Osteoarthritis (OA) is treated as the most famous form of joint arthritis. Objective: It is a slowly developed, disabling joint problem that decrease quality of life (QOL) and affects 14% of adults ages 25 and older and nearly 34% of those ages 65 and older. Interleukin elevation levels have been linked to autoimmune and degenerative diseases, thus in the current study. Methods: We tried to evaluate the level of interleukins (IL-35 and IL-38) in the two diseases and found the relationship between immune system response and disease severity. Three groups (RA, OA and control) have been used in the study. Results: The comparison between the three groups has been done and the results show a high significant increase in the level of IL-35 and IL-38 in both patients groups (RA and OA) as compared with control (p<0.001). Furthermore, a highly significant (p<0.001) elevated Na level with a significant (p<0.001) decrease in K and Ca levels was found in the RA and OA patients compared with the control. Conclusions: The study shows that the rise in the levels of IL-35 and IL-38 declares the instinctive role of interleukins and the immune system in the regulation and severity of RA and OA diseases, the role of this parameter may be clear in the controlling and monitoring the progression of diseases.
Quality Management in Software Development
Authors: Birulia M. D.
Published: September 2024

Introduction. The scientific literature examines various approaches to quality management in information technology (IT). The issues of identifying and correcting defects are worked out, and the possibilities for minimizing them are shown. There are materials on quality management in complex engineering processes. At the same time, there is no detailed description of quality management at each stage of the IT product life cycle, including testing. It should be noted that the coordination of software releases is closely related to quality management, but this process is rarely or fragmentarily considered in the literature. Additionally, the interprocess communication is not taken into account; therefore, there is no comprehensive understanding of quality management in the creation, testing and refinement of software. This study is designed to fill these gaps. The research is aimed at presenting a comprehensive approach that links the theory, practice and methods of software quality management.Materials and Methods. Theoretical and applied literature on the subject were studied, analyzed, and reviewed. The author's professional background in managing the quality of IT products was used. The practices of global suppliers of digital goods and services were taken into account. The author has used these materials and methods to study in detail the issues of software testing and code deployment.Results. A comprehensive model of quality management in software development is elaborated, described and presented in the form of a diagram. Its interconnections with the project management model and the product life cycle, namely: analysis, design, development, testing, deployment, and support, are identified. Principles of quality management at each of these stages are specified. The processes and checks during code deployment are systematized and presented in the form of a diagram. Their features are shown in three environments: during development, testing, and production.Discussion and Conclusion. The algorithm allows quality experts to build the sequence of actions to eliminate detected defects in the future, understand the situation when it is possible (or impossible) to deploy code, and determine the moment when the software should be transferred to the user. In addition, the proposed scheme can be the basis for automating code deployment. The solution will reduce development time. As a result, the product will enter the market faster, which will speed up the payback of costs. The implementation of the model created within the framework of this scientific work into the production practice of IT companies presupposes strategic changes. Their implementation requires significant time and other resources; therefore, the overall transformation process should be divided into parts. The proposed approach is adaptable to the needs of various organizations and products. You can work with individual components to create an optimal plan for achieving quality management goals.
Verification of the results of the calibration of needle hydrophones on the measurement standard NDETU AUV-02-2018
Authors: Shpak Oleksandr , Duviriak Dariia
Published: September 2024

The results of the verification of the calibration of needle hydrophones using the national primary measurement standard of the unit of ultrasonic pressure in the aquatic environment (NDETU AUV-02-2018) are presented. The main objective of the study was to confirm the accuracy of the calibration of needle hydrophones No. 2538 and No. 2515 by comparison with the calibration results obtained on the measurement standard at the Physikalisch-Technische Bundesanstalt (PTB), Germany.
The paper describes the calibration methods used by laboratories to determine the sensitivity of hydrophones, including the two-transducer reciprocity method and the comparison method. The results of the calibration of needle hydrophones in the frequency range from 1 to 10 MHz obtained by the National Metrology Institute of Germany (PTB) and Ukraine (SE Research Institute “Systema”) were evaluated. Furthermore, the level of uncertainty of the calibration results was compared.
The results of the study demonstrated a high degree of consistency in the measurement results. Added to this, the results confirmed the reliability of the results of the calibration of needle hydrophones using the NDETU AUV-02-2018 measurement standard by the calibration method selected and with the measurement equipment used.
The conclusions confirmed the effectiveness of using the national measurement standard NDETU AUV-02-2018 and its conformity with international measurement standards, thus increasing the confidence in the results at the international level. Additionally, the study provides the ground for future international comparisons with measurement standards of other countries.
Evaluation of the measurement uncertainty during the calibration of metal reference gauges of the 2nd category
Authors: Novoselov Oleg
Published: September 2024

The paper considers problematic issues related to ensuring the uniformity of measurements in the field of legal metrology, namely, during the calibration of working measurement standards used for verification of legally regulated measuring instruments. One of the conditions for ensuring the uniformity of measurements is the compliance of any measuring instrument with the requirements that are prescribed in its technical specification, where standardized metrological characteristics are indicated, which allows us to conclude about the suitability of the instrument for measurements in a known range and with a known accuracy.
The procedure for verification of legally regulated measuring instruments establishes a ratio between the expanded measurement uncertainty provided for by the measurement standard and the maximum permissible error of the measuring instruments of no more than one to three. Determining such a ratio is an example of indirect accounting for the measurement uncertainty. The reliability of the assessment of the compliance of a working measurement standard with metrological requirements, which are regulated by the technical specification, depends on the correctness of the procedures for evaluating the measurement uncertainty during calibrations. The paper indicates the problems of updating the existing regulatory framework for the calibration of measuring instruments using reference gauges as an example and ensuring metrological traceability of the results of the calibration of the liquid volume measuring equipment. Attention was drawn to the need to apply in Ukraine the international practice of the standardization of calibration techniques and methods of uncertainty evaluation to ensure the uniformity of measurements.
A procedure for evaluating the measurement uncertainty during the calibration of the reference 2nd-grade gauge by the volumetric method, which is used as a working measurement standard when verifying legally regulated measuring instruments – fuel dispensers for refuelling cars – is proposed.
Study of the Accuracy and Reliability of Dosimetric Measurements for X-ray Beams with Radiation Qualities N-40, N-100, N-200
Authors: Pustovyi Andrii
Published: September 2024

Radiation dosimetry is a critical aspect of medical, industrial, and scientific applications involving ionizing radiation. Accurate measurements of radiation doses ensure the safety and effectiveness of radiological practices, which is essential for protecting patients in medical procedures, maintaining safety in industrial applications, and ensuring accuracy in scientific research.
Leading international organizations conduct research aimed at improving measurement accuracy and the dissemination of measurement units. One of the methods contributing to this effort is various international projects. The National Scientific Centre “Institute of Metrology” has participated in one such international project.
This international project, involving several National Metrology Institutes (NMIs), aimed to improve the accuracy and consistency of radiation dosimetry across Europe. By standardizing measurement and calibration procedures, the project seeks to create a unified system for measuring radiation doses, thereby improving the reliability of ionizing radiation dosimetry.
This project is particularly significant given the continuous increase in radiation-based technologies across various fields. For example, precise measurements of ionizing quantities are crucial in the medical field, especially for radiotherapy, to ensure that patients receive the necessary dose with minimal exposure to surrounding healthy tissues. Similarly, in industrial radiography, accurate dosimetry is essential for meeting safety standards and preventing excessive radiation exposure to workers.
The international project, with the Physikalisch-Technische Bundesanstalt (PTB) and the Central Office of Measures (GUM) as leading organizations, aims to improve key factors in ionizing radiation dosimetry. These include developing reliable calibration protocols for various types of radiation, establishing traceability chains to ensure measurement accuracy, and sharing best dosimetry practices among project participants. Preliminary comparisons were performed between NMIs, with two control participants serving as references while other NMIs participated anonymously (knowing only their number and the numbers of the reference participants). Each participant had the opportunity to compare their obtained values with the reference values and make adjustments for future measurements. The collaborative nature of such cooperation also promotes knowledge and experience exchange, fostering innovation and improvement in dosimetry techniques.
The NSC “Institute of Metrology”, a leading organization in the field of the ionizing radiation metrology, has actively participated in this project as a representative from Ukraine. The paper presents the results of international comparisons for X-ray beams with the radiation qualities N-40, N-100, N-200.
Maneuvering Colonial and Postcolonial Resistances with Poetry: A Comparative Study of Nazrul and Walcott
Authors: Uddin Md. Abu Saleh Nizam , Karim Shah Mohammad Sanaul , Mahmud Mohammad Riaz
Published: September 2024

This article aims to place poems by Kazi Nazrul Islam of Bangla literature in a comparative study with those by the Caribbean poet Derek Walcott. Nazrul wrote when his country India was under British colonial rule and Walcott wrote when his Caribbean region was under British colonialism and in postcolonial period. The study becomes inevitable against a backdrop where comparative studies of Nazrul have been conducted with American and European authors who lack similar colonial backgrounds. Additionally, when Nazrul is compared with non-American and non-European authors, his Islamic identity, which transforms into his all-embracing humanity, is often omitted or sidelined. Thus, when poems by Nazrul and those by Walcott are in a comparative study, the two poets from two different marginalized nations exhibit conspicuous affinities in their poetic resistances. This is how this paper looks forward to doing a comparative study of the poems by Nazrul and those by Walcott by adopting the methods of Traditional Literary Criticism and a new comparative study as shaped by Zepetnek. The results which the study yields are that the poets maneuver identical poetic resistances by addressing the nation’s unity, revival of history, composition of unique literature, concern for the working-class people, and anti-colonial struggle. The results of the research may contribute to raising cultural awareness among marginalized nations about resisting aggression.
Adaptation mechanisms of the Russian labor market in conditions of uncertainty
Authors: Korolyuk Elena V. , Pilipchuk Nadezhda V. , Plyasova Svetlana V. , Shevtsov Nikita A.
Published: September 2024

The relevance of the study is due to the continuous changes in the labor market under the influence of external factors and the need to increase its adaptive abilities in conditions of uncertainty. The purpose of the study is to identify the features of the adaptation of the Russian labor market to the conditions of uncertainty caused by the pandemic, and the development of new forms of employment that ensure the structural transformation of the market and changes in labor relations. The objectives of the study are to analyze new forms of work arising on the basis of transformation of models of interaction between participants in a period of uncertainty; to determine the vector of development of labor relations that ensure the balance of the labor market. Methodology . The study was carried out using methods of theoretical analysis, systematization, economic analysis, graphical method, comparative analysis method, and morphological analysis method. Results . The analysis of the dynamics of the labor market development indicators during the pandemic allowed us to conclude that it was destabilized in the conditions of uncertainty, manifested in the form of a decrease in employment indicators, an increase in unemployment, an increase in tension in the market. By 2021, many indicators of the labor market development have returned to a doc-like level. The activity of the Russian population in the global online labor market is analyzed, as well as the demand of Russian companies for labor on digital platforms. The directions of ensuring greater adaptability of the Russian labor market through the use of various mechanisms of state policy are substantiated. Conclusions . The emergence of new forms of work based on the transformation of models of interaction between participants has been established. It is concluded that accelerated digitalization during the pandemic created opportunities for online employment of the population, which contributed to the partial removal of tension in the Russian labor market.
Economic assessment of innovative development: doctrine, methodology, praxeology. Part II: methodology for calculating the tessitura of innovative economic development
Authors: Kochetkov Sergei V. , Kochetkova Olesia V.
Published: September 2024

The article discusses the challenges of adjusting to the innovative development of the economy. The authors calculated a measure of the influence of factors in innovative economic development, which reveals the directions for intensifying innovative opportunities in Russia. The economic structure of innovative development is also discussed. The article identifies the current state of innovative development in the Russian economy. It also highlights the combinatorial effect of the factors studied on the growth rate of innovative products, services, and works. This information is used to predict future trends and risks in innovative development. Based on this analysis, the authors identified the main patterns and risks of innovative growth in the Russian economy. These findings form the basis for understanding the internalization process of innovation. The article proposes a set of measures for adjusting the innovative development in the Russian Federation. These measures will serve as a basis for ensuring the transition of the economy from searching for growth opportunities to structural and systemic changes, leading to a new quality of development.
Business camp as an effective model for the development of managerial skills of the leaders of children's camps
Authors: Dinner Igor V.
Published: September 2024

The article examines changes that have taken place in the field of children's recreational activities in a market-based economy and the new economic realities that they have brought about. The author compares the way in which the children's recreational system functions and develops in a planned economy with that in a market economy. The article emphasizes the important roles played by the leaders of suburban сhildren's camps, and the changes that are needed to adapt to new realities. The article analyses the new requirements for professional and managerial skills of leaders of children's health camps, as well as discusses issues related to traditional methods of training for country camp managers and suggests more effective ways to develop the professional skills of the management team at children's country camps. The article also describes trends in the decline in the number of children's recreational facilities and how these processes are influenced by the level of expertise of the head of a children's recreational camp. In detail, the article examines the business camp model and its efficacy in terms of developing and enhancing the professional and managerial skills of the head of a health-focused children's camp. Building on research conducted by Russian and international scholars, the author proposes a model of leadership competencies tailored to the specific needs of this field. The article identifies the essential skills that require development for the current leaders of children's camps in suburban areas. The author presents the findings of a study on this model for professional skill development, which demonstrate an improvement in the quality of services provided and a positive trend in the improvement of the management system at a children's camp.