bluuebunny/crossref_metadata_2025 huggingface dataset:
A reappraisal of the role of fever in the occurrence of neurological sequelae following lithium intoxication: a systematic review
Authors: Verdoux Hélène , Debruyne Anne-Laure , Queuille Emmanuelle , Leon J de
Published: March 2022

Aim We aimed to review cases of Syndrome of Irreversible
Lithium-Effectuated Neurotoxicity (SILENT) characterized by neurological
sequelae following acute lithium toxicity and to explore whether
cerebellar sequelae are more frequent in cases presenting with fever
and/or infection. Methods Case reports were identified from: (i) 6
reviews published up to 2005; (ii) MEDLINE, Web of Sciences, Cochrane
Library and PsycINFO search. Results We identified 123 SILENT cases
published from 1965 to 2019, in which cerebellar sequelae were observed
in an overwhelming proportion (79%). Nearly two out of three cases
(63%) had maximal lithium plasma level <2.5 mEq/l (low/mild
toxicity). Fever and/or infection were reported in nearly half of the
patients (48%). The likelihood of presenting with cerebellar vs. other
neurological sequelae was independently increased by elevated plasma
lithium level ( 2.5 mEq/l) (OR=4.36, 95%CI 1.31-14.52, p = 0.02) and
by a history of fever and/or infection (OR=6.48, 95%CI 2.0-21.0, p =
0.002). Conclusions During the SARS-CoV-2 pandemic, prescribers have to
be aware of the risks of cerebral sequelae associated with infection and
fever in lithium users, and should warn them of the need to consult in
case of fever to adjust their lithium dosage. As the occurrence of
SILENT is exceptional, there is no need to modify lithium treatment
preventively because of the pandemic as the benefit/risk balance of this
drug remains largely positive.
Three Cases of Family Occurrence of Moyamoya Disease with RASA1 Mutations
Authors: Li Xun , Ma Miaomiao , Liu Ran , Yang Yun , Yue Wei
Published: March 2022

We report family moyamoya disease consist of a 53-year-old female and
her two 31-year-old daughters, with the second-born daughter encounter
cerebral hemorrhage. CT angiography showed the typical moyamoya disease
change in both case 1-3. Clinical whole exome sequencing was performed
in the three daughters of patient in case 1
The effect of influenza virus infection on pregnancy outcomes: A systematic review and meta-analysis of cohort studies
Authors: Wang Ruitong , Yan Wenxin , Du Min , Tao Liyuan , Liu Jue
Published: March 2022

This meta-analysis was conducted to assess the overall effect of
influenza infection on pregnancy outcomes and provide evidence for
policymakers and relevant healthcare workers. We searched PubMed,
Embase, Cochrane Library and Web of Science from 21 May 1953 to 4
November 2020 to identify cohort studies that investigated the effect of
influenza on pregnancy outcomes. We conducted meta-analysis using
random-effects or fixed-effects models to estimate the pooled effect of
influenza virus infection on selected pregnancy outcomes by risk ratio
(RR) and its 95% confidence interval (CI) on pregnancy outcomes
involving stillbirth, preterm birth, small for gestational age (SGA),
fetal death and low birth weight (LBW). 17 eligible studies involving
2,351,204 pregnant women were included. The pooled effect of influenza
virus infection on stillbirth was significant (RR = 3.62, 95% CI:
1.60-8.20), while no significant effect on preterm birth (RR=1.17,
95%CI: 0.95-1.45), fetal death (RR=0.93, 95%CI: 0.73-1.18,), SGA
(RR=1.10, 95%CI: 0.98-1.24) and LBW (RR=1.88, 95%CI: 0.46-7.66) was
observed. In the subgroup analysis of LBW outcome, the pooled effect was
significant in studies that investigated cohorts diagnosed of influenza
during the 2009 H1N1 pandemic period (RR = 2.28, 95%CI: 1.81 - 2.87),
while there was no significant effect in pre-pandemic or post-pandemic
studies. By this meta-analysis, we can say that influenza virus
infection is associated with a higher risk of stillbirth among pregnant
women, while the effect on preterm birth, fetal death, small for
gestational age and low birth weight await to be further explored.
Fear, anxiety, burnout, and insomnia levels of healthcare workers during COVID-19 pandemic in Turkey
Authors: Yılmaz Yavuz , Erdoğan Ali , Bahadır Erdi
Published: March 2022

Rationale, aims and objectives: This study aims to assess fear, anxiety,
anxiety sensitivity, burnout, and insomnia of healthcare workers (HCWs)
during novel coronavirus-2019 (COVID-19) outbreak and to identify their
relation to sociodemographic and clinical characteristics. Method:
Totally 600 HCWs were included in this cross-sectional study. A
Sociodemographic Data Form, Coronavirus Anxiety Scale (CAS), Fear of
COVID-19 Scale (FCV-19S), Anxiety Sensitivity Index-3 (ASI-3), Maslach
Burnout Inventory (MBI), and Insomnia Severity Index (ISI) were used.
Results: Of participants, 364 were females and 236 were males with a
mean age of 33.49±7.29 years. About 95.3% of HCWs had a fear of
infecting their loved ones. Mean MBI and ISI scores were significantly
higher among HCWs working in COVID-19 clinics and intensive care units
(p=0,000; p=0,039). Mean CAS, FCV-19S, MBI, and ISI scores were
significantly higher in women than men (p=0,000; p=0,000; p=0,027;
p=0,005). Mean CAS and ISI scores were significantly higher among nurses
(p=0,008; p=0,004), while mean ASI-3 of the other HCWs and MBI scores of
physicians were significantly higher (p=0,009; p=0,000). Conclusion: The
COVID-19 pandemic is a major health issue associated with psychiatric
illnesses in HCW subgroups with distinct sociodemographic
characteristics. It is of utmost importance to develop individualized
preventive and therapeutic psychiatric services for HCWs.
Trends in Hysteroscopic Endometrial Sampling in Women 70 Years or Older
Authors: Bar-On Shikma , Solomon Neta , Rattan Gilad , Ben-David Alon , Grisaru Dan
Published: March 2022

Objective: To characterize office and operating room hysteroscopy in
women 70 years of age or older. Design: This was a retrospective chart
analysis. Setting: A single tertiary-care medical center. Population:
All women aged 70 years of age or older who underwent a hysteroscopy
procedure between March 2011 and August 2018. Methods: All hysteroscopic
interventions performed during the study period were reviewed. All
patients had at least one gynecological examination that included an
ultrasound study prior to the hysteroscopy. Main outcome measures:
Primary outcomes included procedure success and histopathological
findings. Secondary outcomes included short-term complications of the
procedure. Results: The data of 577 patients were analyzed. The median
age at the time of the procedure was 76 years. 225 office hysteroscopy
procedures and 405 operating room procedures were included. Of the 236
patients with PMB, 73(30.9%) were diagnosed as having malignancy
compared to 25 (7.3%) of the 341 patients with no PMB (p <
.001, odds ratio (OR) = 5.66; confidence interval (CI) 3.46-9.26). The
office procedure was successful in 194 (87%) patients. 53 patients
required a second hysteroscopy, which revealed 12 cases of premalignant
or malignant lesions. The volume of procedures in the office increased
16 times during the study period. Conclusions: Office hysteroscopy for
women over the age of 70 is safe, feasible, and reliable for diagnosis
of endometrial malignancy. Failed hysteroscopy and a moderate-to-high
index of suspicion for malignancy indicates the need for a repeat
hysteroscopy. The diagnostic yield using the office procedure has
increased over time.
Identification of GLP1R and MCHR1 signaling as novel GPCR targets of MRAP2 protein
Authors: Wang Meng , Xu Jing , Lei Xiaowei , Zhang Cong , Zhe Kuang , Lan Haifeng , Li Qingfen , Zhang Chao
Published: March 2022

The seven trans-membrane spanning G protein couple receptors(GPCRs)
constitute the largest family of FDA approved drug targets to treat
numerous human diseases, including metabolic associated disorders. The
Melanocortin Receptor Accessory Protein 2 (MRAP2), a small single
transmembrane protein broadly expressed in multiple tissues has been
defined as a vital endocrine pivot of five melanocortin
receptors(MC1R-MC5R) and several other GPCRs in the regulation of
central neuronal appetite and peripheral energy homeostasis. However,
MRAP2 null mouse model exhibited late onset obesity syndrome without
alteration on the eating behavior, a huge phenotypic departure from MC4R
KO animals. In this study, we identified GLP1R and MCHR1, the two energy
regulators as novel GPCR targets and characterized the specific regions
of MRAP2 protein that required for the pharmacological modulation of the
intracellular cAMP cascades. The simultaneous inhibitory effect of MRAP2
on the anorectic GLP1R and orectic MCHR1 signaling further elucidated
the complex endocrine network of GPCR signaling which may explain the
composite metabolic phenotypes of MRAP2 deficiency.
Pits and tracheids explain the hydraulic safety- but not the hydraulic efficiency of 28 conifer species
Authors: Song Yanjun , Poorter Lourens , Horstling Angelina , Delzon Sylvain , Sterck Frank
Published: March 2022

Conifers face increased mortality risks following severe droughts that
cause drought-induced cavitation in their vascular system. Drought
responses are strongly species-dependent because variation in cavitation
resistance may result from species differences in pit structure and
function since pits control the air seeding between water transporting
conduits. This study aims to quantify variation in cavitation resistance
and hydraulic conductivity for 28 conifer species grown in a common
garden experiment and assesses the underlying mechanisms. Conifer
species with a small pit aperture, high pit aperture resistance and
large valve effect were more resistant to cavitation, implying that they
all contributed to reduced air seeding. Hydraulic conductivity was not
explained by tracheid and pit traits; it, only increased with thinner
tracheid cell walls which may reduce the flow resistance between
adjacent tracheids. Overall, pit traits were stronger phylogenetically
controlled than tracheid wall thickness. Conifers differed in hydraulic
safety and hydraulic efficiency, but there was no trade-off amongst
these functions because they are driven by different xylem anatomical
traits and therefore also in phylogenetic control.
Variation of xylem traits reveals evidence of adaptation to climatic conditions in conifers along a latitudinal gradient across China
Authors: Zheng Jingming , Li Yajin , Morris Hugh , Vandelook Filip , Jansen Steven
Published: March 2022

Extant conifer species are adapted to a range of climate conditions,
which would be reflected in their xylem structure, especially in
tracheid characteristics of early-and-latewood. With an anatomical
dataset of 79 conifer species native to China, an interspecific study
was conducted within a phylogenetic context to find latitudinal patterns
in tracheid cell dimensions in response to climate. The analyses showed
that there is a significant difference in tracheid length and diameter
between early-and-latewood, but no significant difference in cell wall
thickness. An opposite divergence pattern was found based on the PC1
axis of tracheid traits, with species of Pinaceae showing strong
divergence in their xylem structure in contrast to a conservative xylem
structure for species of the other families studied. Except for tracheid
diameter in earlywood, tracheid characteristics decreased as latitude
increased. Mean annual temperature, precipitation, and their interaction
could explain 24.7% to 49.2% of the variance of the tracheid features
measured, while phylogeny accounted for 12.5 to 50.5%, suggesting that
both temperature and precipitation play a major role in shaping conifer
xylem structure. These results provide valuable insight into the effect
of climate on the xylem structure of conifers, helping to further our
understanding of trees’ adaptation to climate.
A new fractional order chaotic dynamical system and its synchronization using optimal control
Authors: PATIL MADHURI , Bhalekar Sachin
Published: March 2022

In this work, we introduce a new three-dimensional chaotic differential
dynamical system. We find equilibrium points of this system and provide
the stability conditions for various fractional orders. Numerical
simulations will be used to investigate the chaos in the proposed
system. A simple linear control will be used to control the chaotic
oscillations. Further, we propose an optimal control which is based on
the fractional order of the system and use it to synchronize the new
chaotic system.
The Duration of Relief of Symptoms After Treatment in Symptomatic COVID-19 Cases
Authors: Timurkaan Mustafa
Published: March 2022

Background: The clinical profile of coronavirus disease (COVID-19) has a
wide range of symptoms from self-limiting viral upper respiratory tract
infection to death from arrest. The symptoms vary depending on the
severity of the disease and countries. Experts from many parts of the
world report on symptoms and onset times, but there are still many
unanswered questions about the new disease, COVID-19. The prevalence of
symptoms and, in particular, the relief durations are also questions
that need to be answered. Moreover, there is no common algorithm for
post-treatment follow-up in this disease, which can cause many organ
damage. Method: The aim of this cross-sectional survey study is to find
answers to these questions. A total of 185 symptomatic people, who were
discharged after inpatient treatment in Elazig Fethi Sekin City Hospital
in Turkey in December 2020, voluntarily participated in the study.
Volunteers were asked questions about the duration of relief of symptoms
after treatment. Results: According to the answers of the participants,
it was concluded that the symptoms could persist for more than 1 month
and therefore they repeatedly applied to the hospital. Conclusion: The
uncertainty about the symptoms and duration of COVID-19 after treatment
imposes serious financial burdens on health organizations. Due to this
reason, it is urgently necessary to conduct large-scale randomized
studies and determine follow-up algorithms after treatment.
An iterative method to compute dual solutions on a class of nonlinear higher order SBVPs arising in MBE
Authors: Pandit Biswajit , Verma Amit , Agarwal Ravi P.
Published: March 2022

In this work, we focus on the following non-linear fourth order SBVP
\begin{eqnarray} \nonumber
\frac{1}{r}\left[ r
\left\lbrace
\frac{1}{r} \left(r
\phi’ \right)^{’}
\right\rbrace^{’}\right]^{’}=\frac{\phi’
\phi’‘}{r}+\lambda,
\end{eqnarray} where $\lambda$ is a
parameter. We convert this non-linear differential equation into third
order non-linear differential equation, which is given by
\begin{eqnarray} \nonumber
\frac{1}{r}\left[ r
\left\lbrace
\frac{1}{r} \left(r y
\right)^{’}
\right\rbrace^{’}\right]^{’}=\frac{y
y’}{r}+\lambda. \end{eqnarray} The
problem is singular, non self adjoint, nonlinear. Moreover, depending
upon $\lambda$, it admits multiple solutions. Hence, it
is too difficult to capture these solutions by any discrete method such
as finite difference etc. Here we propose an iterative technique by
using homotopy perturbation method (HPM) with the help of variational
iteration method (VIM) in a suitable way. We compute these solutions
numerically. Convergence of this series solution is studied in a novel
way. For small positive values of $\lambda$, singular
BVP has two solutions while solutions can not be found for large
positive values of $\lambda$. Furthermore, we also find
dual solutions for $\lambda <0$.
High figure of merit in Half Heusler semiconductor RhNbZ with(Z = Ge, Sn)
Authors: BOUDJELTIA Mohammed Amine , aziz zoubir , TERKHI Sabria , BENNANI Mohammed Abderrahim , Bouadjemi Bouabdellah , BENIDRIS Mansour , Bentata Samir , KHANDY Shakeel Ahmad
Published: March 2022

Using the Full Potential Linearized Augmented Plane Wave FP-LAPW, as
implemented in the Wien2k package. The structural, electronic, magnetic
and elastic properties of the Half Heusler (HH) RhNbGe and RhNbSn were
investigated. The Generalized Gradient Approximation (GGA) and the
Tran-Blaha-modified Becke-Johnson exchange potential method (TB-mBJ) was
applied to model the exchange correlation potential. Our results show
that the both compounds studied are mechanically stable. Moreover, RhNbZ
(Z:Ge,Sn) presents a semiconductor behavior obeying the Slater-Pauling
rule. The thermodynamic properties, in particular the Bulk modulus, the
heat capacity, the Debye temperature and the thermal expansion
coefficients of the two alloys are investigated using the quasi-harmonic
Debye model. The semi-classical Boltzmann theory, as implemented in the
BoltzTraP code, is used to study thermoelectric properties. The high
values obtained figures of merit ZT of RhNbGe and RhNbSn compounds make
them promising candidates for thermoelectric applications at low and
high temperatures.
Evaluation of Left ventricle ejection fraction, Serum Ferritin and C - reactive protein as Early Prognostic Markers in Children with Sepsis.
Authors: Ismail ahlam , Ela Mostafa Abu , Roshdy Islam , Sabry Nagwa
Published: March 2022

Sepsis, still cause morbidity and mortality in children admitted to the
pediatric intensive care unit (PICU). Several diagnostic and biological
markers have y been studied to monitor unfavorable evolution of sepsis
in critically ill patients but didn’t established. Objective: This study
aimed to evaluate the Left ventricle ejection fraction, serum Ferritin
and C - reactive protein and find out their value as early prognostic
markers for outcomes in pediatric sepsis in PICU. Patients and Methods:
40 patients admitted to a PICU diagnosed with sepsis. Echocardiography
study: to figure out the ejection fraction (EF) of the left ventricle,
serum levels of C-reactive protein and ferritin on D1 and D3 after
admission. Patients followed to detect their outcomes and mortality.
Results: We found with cardiac dysfunction by echocardiogram and
elevated ferritin levels on D1 had longer hospital stay in, prolonged
duration of mechanical ventilation use, higher maximum inotropic score,
and fewer ventilator-free hours. Both low Left ventricle ejection
fraction and high serum Ferritin are associated with unfavorable
outcomes. Conclusion: Cardiac dysfunction by echocardiogram (EF
< 55%) and serum ferritin values (≥300 ng/mL) on D1 of
admission in pediatric patients with sepsis admitted to the PICU, were
significantly associated with unfavorable outcomes.
Radiating and reacting MHD unsteady flow past an exponentially accelerated inclined permeable plate in a porous medium with Soret effect
Authors: Bijjula Prabhakar Reddy , Hugo Alfred
Published: March 2022

In this research paper, we numerically analyzed the effects of Soret and
magnetic field on radiating and chemically reacting MHD unsteady free
convective flow past an exponentially accelerated inclined permeable
plate embedded in a saturated porous medium of uniform permeability with
variable temperature and concentration numerically. The model’s
dimensionless coupled non-linear PDEs are solved numerically by using
the finite difference method. The influence of key parameters on the
velocity, temperature and concentration fields are discussed graphically
whilst the numerical results of skin-friction, Nusselt and Sherwood
numbers are exhibited in tabular form. The results obtained show that
the permeability of the medium, thermal and mass buoyancy force improves
the fluid velocity whilst the magnetic field and inclination angle have
reverse effect. The fluid velocity and temperature decreases with an
increment in radiation parameter whilst the reverse trend is observed in
case of Nusselt number. The Soret effect is to elevate the fluid
velocity and concentration whilst chemical reaction rate has reverse
impact and these parameters have opposite effect on the Sherwood number.
This flow model has various industrial applications in the field of food
processing, polymer production, inclined surfaces in a seepage flow,
design of fins, etc.
MHD Casson nano fluid over a nonlinear penetrable elongated sheet with thermal radiation and chemical reaction
Authors: Vyakaranam Seethamahalakshmi , G Venkata Ramana Reddy
Published: March 2022

Consider a steady flow in two-dimensional of a viscous, incompressible
Casson nano liquid over a nonlinear penetrable elongated sheet with
radiation and chemical reaction. The Casson liquid rheological model is
used to explain the non-Newtonian liquid attributes. Similarity
variables are utilized to evaluate the governing flow model into set of
nonlinear total differential equations. The outcomes of the flow
equations were gotten by using Runge-Kutta alongside the shooting
techniques. In other to explain the physics of the problem, impact of
flow parameters are presented in graphs while computations on
engineering curiosity are presented in table. Ahike in the Casson liquid
term is observed to degenerate the fluid velocity alongside the momentum
layer thickness. The impact of the imposed magnetic is felt by
decreasing the velocity owning to the Lorentz force
Copper tolerance of wheat plants mediated by TaGST1 gene and it upstream regulatory factor WRKY74
Authors: Li Ge-Zi , Zheng Yong-Xing , Chen Shi-Juan , Liu Jin , Wang Pei-Fei , Wang Yong-Hua , Guo Tian-Cai , Kang Guo-Zhang
Published: March 2022

Copper (Cu) is an important plant micronutrient; however, excessive Cu
can disturb the protein structure, affect plant growth and development,
and pose as a potential human health risk. Glutathione S-transferase
(GST) is the key enzyme in glutathione (GSH) synthesis; thus, it plays
crucial role in Cu detoxification. Nonetheless, its regulatory
mechanisms remain largely unclear. In this study, we identified a
Cu-induced glutathione S-transferase 1 (TaGST1) gene in wheat. Yeast
one-hybrid (Y1H) between TaGST1 promoter and Cu-stressed wheat leaf cDNA
library was performed and screened out TaWRKY74 transcription factor.
Their bind were further verified by using another Y1H and luciferase
(LUC) assays Functions of TaWRKY74 were further tested by using
transiently silence and overexpression methods. Under Cu stress,
TaWRKY74 and TaGST1 expression, GST activity, and GSH content were
significantly inhibited in transiently TaWRKY74-silenced wheat plants.
However, the contents of hydrogen peroxide (H2O2), malondialdehyde
(MDA), and Cu were significantly increased in these silenced wheat
plants. Further investigation found that transiently ectopic
overexpression of TaWRKY74 increased GSH content, whereas decreased MDA
content during Cu stress. Notably, exogenous application of GSH could
reversed the adverse effects of transiently TaWRKY74-silenced wheat
plants during Cu stress. Taken together, our results suggested that
TaWRKY74 regulated TaGST1 expression and affected GSH accumulation under
Cu stress, and could be useful to ameliorate Cu toxicity for crop food
safety.
Current Impact of Three-Dimensional Echocardiography
Authors: Gill Edward , Nanda Navin
Published: March 2022

Three-dimensional echocardiography has emerged as an important tool
within the Echocardiography armamentarium. We present a series of
special articles that review important topic where 3D Echocardiography
is particularly important for evaluation, including structural heart
interventions.
Failed expectations: can deliberative innovations produce democratic effects in hybrid regimes?
Authors: Fiket Irena , Ilic Vujo , Pudar-Drasko Gazela
Published: March 2022

Participation in deliberation in stable democracies produces effects which are beneficial for democracy, while the results of deliberative innovations in non-democracies are more ambiguous. This article contributes to the debate about the effects of participatory democratic innovations on attitudes, related to democratic commitments, political capacities and political participation, in the increasingly ubiquitous hybrid regimes. We present the evidence collected from the participants before and after deliberative mini publics (DMPs), held in Serbia in 2020. Serbia is an exemplary case of a recent wave of autocratization, which had led to it becoming a hybrid regime, and it had no track record of deliberative innovations. When conducting the mini publics, we introduced an innovation in the standard design, by including active citizens - representatives of local initiatives or social movements particularly interested in the issue of DMPs. We could not find evidence that the democratic innovation affected attitudes of participants regarding democratic commitments, political capacities and political participation. However, we did find that participants of the DMPs became less satisfied with the functioning of the democracy on the local level. We argue that the anti-democratic wider context of hybrid regimes can produce adverse effects when introducing participatory democratic innovations, at least when it comes to this specific dimension of political participation. We conclude with the suggestions for further research, and a call for consideration of the wider political context when designing democratic interventions in hybrid regimes.
ANALISIS POTENSI BATU KAPUR MENGGUNAKAN PENGINDERAAN JAUH DI KECAMATAN MUARADUA, OKU SELATAN
Authors: Agung Irena Anna Elfianti , Armijon Armijon , Murdapa Fauzan
Published: March 2022

Kecamatan Muaradua, Kabupaten OKU Selatan termasuk dalam Formasi Baturaja yang salah satu batuan pembentuknya yaitu batu kapur. Wilayah ini dijadikan sebagai salah satu rencana lokasi tambang batu kapur oleh PT. Semen Baturaja (Persero) Tbk guna memenuhi kebutuhan bahan baku untuk proses produksi semen. Dalam penentuan rencana lokasi tambang, perlu dilakukan kajian awal untuk menentukan daerah yang memiliki potensi batu kapur. Penelitian ini memanfaatkan data citra Landsat 8 yang diolah dengan menggunakan algoritma NDVI dan LST untuk mendapatkan indeks vegetasi dan suhu permukaan tanah, serta dilakukan interpretasi dan klasifikasi citra untuk mendapatkan tutupan lahan pada wilayah penelitian. Seluruh parameter dilakukan overlay, kemudian skoring dan pembobotan melalui dua tahapan. Uji akurasi untuk hasil klasifikasi citra menggunakan matriks konfusi. Hasil dari penelitian ini menunjukkan bahwa potensi batu kapur di Kecamatan Muaradua didominasi oleh kelas potensi sedang, namun terdapat pula daerah-daerah yang memiliki kelas potensi tinggi dan sangat tinggi. Daerah-daerah ini berada sebagian besar terletak di Desa Gunung Tiga, serta tersebar di sekitar Desa Pendagan, Datar, dan Gunung Terang. Dari hasil penelitian ini, daerah-daerah yang memiliki kelas potensi tinggi dan sangat tinggi dapat dijadikan sebagai lokasi untuk melakukan kajian awal penentuan rencana lokasi tambang baru bagi perusahaan.
PEMODELAN PROPERTI ELASTIK DAN ANISOTROPI PADA BATUSERPIH ORGANIK IMMATURE
Authors: Sudrazat Sthevanie Dhita , Herawati Ida
Published: March 2022

Batuserpih organik merupakan salah satu reservoar non konvensional yang memiliki heterogenitas dan struktur yang kompleks. Pemodelan fisika batuan pada batu serpih organik penting dilakukan untuk mengetahui karakteristik dari reservoar tersebut. Penelitian ini bertujuan untuk mengetahui pengaruh kerogen dan mineral terhadap properti fisis dan sifat anisotropi dari batuserpih organik. Pemodelan dilakukan dengan menggunakan: teori efektif medium Kuster Toksöz untuk menggabungkan fluida dan solid pada masing-masing matriks, Self-Consistent Approximation (SCA) untuk mengetahui properti fisis dari keseluruhan batuserpih, serta Backus Average untuk menentukan parameter anisotropi dari batuserpih organik. Penelitian ini melakukan perhitungan rasio Vp/Vs, impedansi akustik, dan parameter anisotropi untuk tingkat kematangan immature dengan variasi mineral lempung serta jumlah material organik. Hasil penelitian menunjukkan bahwa rasio Vp/Vs, impedansi akustik dan parameter anisotropi batuserpih sangat sensitif terhadap kandungan material organik dan variasi mineralogi. Kesimpulan dari penelitian ini bahwa peningkatan kandungan material organik menurunkan rasio Vp/Vs dan impedansi akustik batuan, namun meningkatkan sifat anisotropi. Sementara itu, peningkatan kandungan mineral lempung meningkatkan rasio Vp/Vs namun menurunkan impedansi akustik, serta meningkatkan nilai parameter anisotropi.
ANALISIS CARBON CAPTURE STORAGE DARI EKSPLORASI MIGAS DALAM MENCAPAI SUSTAINABLE DEVELOPMENT GOALS
Authors: Amina Stefanny Rizika , Deborah Amanda T , Wajdi Muhammad D
Published: March 2022

Sebagai salah satu negara penghasil hidrokarbon terbesar di Asia Tenggara, saat ini Indonesia masih menggarap cadangan energi yang terdampak dari penundaan eksplorasi sumur pada tahun 2020. Kondisi target eksplorasi pada cekungan di wilayah Indonesia membutuhkan peran seluruh pemangku kebijakan dalam mencegah dan mengurangi emisi CO2 yang dihasilkan dari sumur minyak dan gas yang mati, lapangan minyak dan gas yang sudah tua, dan blok yang berpotensi untuk eksplorasi minyak dan gas. Pada kajian ini, terdapat analisis CCS dengan mengidentifikasi karakteristik dari penyekat patahan, menganalisis sekuestrasi yang bekerja tepat untuk blok migas, serta analisis terhadap isu SDGs dengan sudut pandang analisis SWOT dan PESTLE di Indonesia. Langkah ini sejalan dengan Rencana Aksi Nasional Indonesia dalam mengurangi hingga 40% emisi CO2. Dalam studi ini, keikutsertaan dari para pegiat industri dan pemangku kebijakan dalam rangka pencapaian SDGs sangat krusial dari berbagai aspek. Hal ini diperlukan untuk melancarkan transformasi besar dari sistem energi global agar mampu mengubah prospeksi untuk merealisasikan tiga nilai SDGs yang terkait dengan energi, yaitu mengurangi dampak kesehatan yang parah akibat polusi udara (SDGs no.3), untuk mencapai akses energi yang terjangkau secara menyeluruh (SDGs no.7), dan untuk mengatasi perubahan iklim (SDGs no. 13).
Cover JGE
Authors: JGE Editor
Published: March 2022

Cover JGE
Non jaagsiekte retrovirus associated adenosquamous lung carcinoma in a goat
Authors:   Professor Firmino Marsico Filho University  Veterinary Hospital, Fluminense Federal University, Consalter Angélica , Guerra Juliana M. ,   Pathology Center, Instituto Adolfo Lutz, São Paulo, SP, Leite Juliana S. ,   Department of Pathology and Clinical Veterinary, Faculty of Veterinary, Fluminense Federal University, Réssio Rodrigo A. ,   Pathology Center, Instituto Adolfo Lutz, São Paulo, SP, Barbosa João Marcos S. ,   Clinical and Animal Reproduction, Fluminense Federal University, Ferreira Ana Maria R. ,   Clinical and Animal Reproduction, Fluminense Federal University, Balaro Mario Felipe A. ,   Faculty of Veterinary, Fluminense Federal University
Published: March 2022

An 11-year-old pet goat presented a clinical history of acute respiratory distress with ultrasound diagnosis of wide lung injury. The animal was euthanized due to welfare reasons. At necropsy, it was found pleural effusion and adhesion on the right cranioventral thoracic region. The right cranial and middle lung lobes were firm and light gray with a neocavity containing purulent exudate. From the middle lobe, there was a nodular proliferation occupying alveolar spaces, densely cellular and composed by cuboid-columnar epithelial cells arranged in papillae and acini (60%), as well as polygonal cells arranged in nests with squamous differentiation (40%). Marked pleomorphism, anisocytosis and anisocariosis were also noted. A total of 39 mitosis figures for ten fields at 400x magnification were counted. Lung samples were negative for jaagsiekte retrovirus (JSRV) by PCR. Immunostaining for TTF1 and P53 occurred in zones of adenomatous and squamous differentiation, respectively. In MIB-1, 14% (82/594) of immunolabeled cells were observed in the squamous component. In conclusion, the histopathological and immunohistochemical characteristics confirmed the diagnosis of a pulmonary adenosquamous carcinoma, without JSRV involvement, in goat species.
Analysis Journal of Habits of Mind Through the Realistic Mathematics Education (RME) Approach in Improving Reasoning Ability
Authors: Simarmata Ezra P
Published: March 2022

The purpose of this study was to determine: (1)The tendency of the habits of mind towards reasoning abilities, (2) the effect of Realistic Mathematics Education (RME) in improving reasoning abilities, and (3) the advantages and disadvantages of Realistic Mathematics Education (RME). This study uses a qualitative descriptive research with a literature study method in the Digital Library of the State University of Medan. The data analysis technique used is the data analysis technique of Miles and Huberman, which consists of the stages of data collection, data reduction, data presentation, and drawing conclusions. The results of the analysis obtained are: (1) Habits of mind affect reasoning ability with an average effect size value of 1.131687 in the high category. (2) Realistic Mathematics Education (RME) has an effect on reasoning ability with an average effect size value of 1,572938 in the very high category. (3) The advantages of the RME approach are that students are more active in building their own knowledge, the learning process becomes more interesting because it uses real experiences / problems in everyday life that occur around them, and students are given the opportunity to think, argue mathematically on solving problems. which are given. Meanwhile, the advantages of the RME approach are that in the learning process the smarter group dominates than the less intelligent group, the low level of teacher ability results in misconceptions about the material, the use of time in the RME approach process is quite long and the search for questions related to the RME approach. the hard one
Inductance and Compression Forces in Double-Layer Coils
Authors:   Krylov State Scientific Center, TSITSIKYAN Georgiy N. , BOBROVNIKOV Petr V. ,   Krylov State Scientific Center
Published: March 2022

Expressions for calculating the self-induction coefficients of two-layer and single-layer coils are considered, and related comparisons are carried out. Examples of calculating the induction coefficients for known design versions of coils are given. An expression for calculating axial compression forces in two-layer coils is presented. The axial compression forces in coils as part of three-phase load devices designed for testing generator sets of autonomous power plants have been calculated. The expressions obtained for calculating the inductances and axial compression forces in two-layer coils are quite concise and can be recommended for practical use. These expressions include only the coil design parameters: the number of turns in the layers, layer radii, winding pitches, and layer lengths. The article is illustrated with particular examples of calculating the coil inductance and compression forces.
The Institutional Work of IFRS adoption in Telco Company: Transformation from US GAAP to IFRS
Authors: Susliani Winda , Wahyuni Ersa Tri , Puspitasari Evita
Published: March 2022

AbstractThe literature on the IFRS adoption process to date has mainly focused on the macro level. This paper draws on an in-depth longitudinal analysis of the Indonesian company PT Telekomunikasi Indonesia Tbk to understand the role of institutional work in the transformation of organization from US GAAP to IFRS. The paper examines the work of actors to disrupt, create, and maintain the institution during the transition to IFRS. The study has revealed that the IFRS adoption at the company is beyond a shallow compliance of financial reporting standards but has significant impact on the company’s transformation as a whole. The IFRS adoption has transformed the business process and the organization culture. The study has also revealed that there are different types of institutional works during the four stages of institutional transformation of the company: Stability, Conflict, Change and Implementation. The tone of the top management board in the organization is crucial to the key actors to stay committed to the long transformation process. This paper contributes to the literature of the IFRS adoption process by providing a framework of the IFRS adoption at the micro level. The case study may assist other companies in their real transformation through embracing the IFRS.   AbstrakLiteratur tentang proses adopsi IFRS sampai saat ini terutama berfokus pada tingkat makro. Makalah ini mengacu pada analisis longitudinal mendalam dari perusahaan Indonesia PT Telekomunikasi Indonesia Tbk untuk memahami peran kerja institusional dalam transformasi organisasi dari US GAAP ke IFRS. Makalah ini mengkaji pekerjaan para aktor untuk mengganggu, menciptakan, dan memelihara institusi selama transisi ke IFRS. Studi tersebut telah mengungkapkan bahwa adopsi IFRS di perusahaan berada di luar kepatuhan standar pelaporan keuangan yang dangkal tetapi memiliki dampak signifikan pada transformasi perusahaan secara keseluruhan. Adopsi IFRS telah mengubah proses bisnis dan budaya organisasi. Studi ini juga mengungkapkan bahwa ada berbagai jenis pekerjaan institusional selama empat tahap transformasi institusional perusahaan: Stabilitas, Konflik, Perubahan dan Implementasi. Nada dewan manajemen puncak dalam organisasi sangat penting bagi para aktor kunci untuk tetap berkomitmen pada proses transformasi yang panjang. Makalah ini berkontribusi pada literatur proses adopsi IFRS dengan menyediakan kerangka kerja adopsi IFRS di tingkat mikro. Studi kasus dapat membantu perusahaan lain dalam transformasi nyata mereka dengan merangkul IFRS.
The relationship between characteristics of extraversion, conscientiousness and versatility with job performance
Authors: Dehaki Masoumeh Esmaeili
Published: March 2022

The aim of this study was to examine the relationship between conscientiousness and versatility characteristics and impact of these two traits with job performance province Kerman's Department of Education. Methodology: To perform this research evaluated extensive theoretical research in the field of personality and job performance. Results: Special relationship took based on scientific literature and who opinion of experts and all the hypotheses of this study are based on established, The population of the study consisted of a total staff of education s Kerman is 330 people. Data was collected using questionnaires and by using SPSS software were analyzed through descriptive and inferential. Conclusion: Results showed a significant relationship between conscientiousness and versatility and also there is positively and directly the relationship between personality traits variable and job performance.
Investigating the Effects of Cognitive and Metacognitive Learning Strategies to Increase Student Motivation and Probation
Authors: Hojati Mahbobe , Rezaei Fatemeh , Iravani Mohammadreza
Published: March 2022

The method of this study is Semi-experimental research method boy and girl first academic semester of probation, Methodology: including 200 students, of whom 50 were selected using stratified random sampling. And Bagmarsh randomly into two control groups (n = 25 for each group) were divided. Results: Instruments included the Academic Motivation Scale Harter and the average score of students in the second semester of the 2013- 2014 school year. Conclusion: The results of the data using analysis of covariance showed that cognitive and metacognitive strategies training have a positive effect on students' motivation.
The Ambivalences of English Lessons Existing in Indonesian Primary Schools
Authors: Astutik Yuli , Munir Ahmad
Published: March 2022

This article discusses policies governing the English curriculum in Indonesian primary schools. English, as local content or as an extracurricular subject delegated to each school, creates inequality in primary school education as some primary schools offer English learning and many do not, for various reasons such as a lack of qualified human resources at TEYL, or insufficient facilities. This ambivalence eventually creates problems at the primary education level, including a lack of clarity regarding careers for English teachers in primary schools. This results in a limit on the number of tertiary institutions that provide English-teaching education for EYL, so that primary schools in turn employ classroom teachers who have no credentials to teach English in the classroom. This ambivalence would not have occurred if the government had made a firm decision on the existence of English as a subject in Indonesian primary schools. Therefore, the authors of this article make an argument for the importance of mastering English as an international language (EIL) for young learners in non-English-speaking countries, especially in this era of rapid technological development. This article suggests that the government should immediately establish a clear policy regarding the status of English as a primary school subject, and that the curriculum policy in primary schools should no longer designate English as a local content or extracurricular subject, but rather as a compulsory subject which automatically adjusts learning outcomes based on student demographic characteristics. The implication of this article is that English lessons can be taught to all young learners through an eclectic approach.
The Role of the Bacteroides spp. in Bacteraemia
Authors: Wysocki Mateusz , Kierzkowska Marta , Podsiadły Edyta
Published: March 2022

Anaerobic bacteraemia is not frequent (1.2–13.7%), but is associated with a high mortality rate of 16–27%. Anaerobic infections including bacteraemia nearly always arise from contamination by endogenous bacteria into contiguous or other sites like gastrointestinal tracts, genito-urinary tracts, abscesses etc. Factors leading to anaerobic bacteraemia are mainly surgical procedures, crush injuries, the presence of foreign bodies, tissue necrosis, tumours, diabetes. The most common infectious anaerobic agents are Gram-negative bacilli belonging to the Bacteroides/Parabacteroides, which under normal conditions constitute the natural human microflora. An important factor in the virulency of B. fragilis is the ability to form abscesses; a limited infection may progress to bacteraemia and then systemic inflammatory response syndrome and sepsis. Anaerobic bacteraemia mainly affects adults, with elderly patients over 65 years with underlying diseases. The importance of anaerobic bacteria in neonatal bacteraemia and sepsis is a relatively new phenomenon. In contrast the prevalence of anaerobes in bloodstream infections in children is extremely rare with children between 2 and 6 years of age having the least risk ranging 0–0.5% overall. The incidence of recovery of anaerobes in neonatal bacteraemia varies between 1.8% and 12.5%. The majority of cases reported in the literature were due to Bacteroides spp. (41%) other cultured anaerobes belonged to Clostridium spp. (32%), Peptostreptococcus spp. (20%).

Blood cultures remain the gold standard for detection of the etiologic both anaerobes and aerobes agent of bloodstream infection. In recent years significant progress has been made in the methods used in the diagnosis of anaerobes, which significantly reduced the time and cost of the examination. Currently, the mass spectometry MALDI-TOF MS and 16S rRNA sequencing are increasingly used for anaerobic bacteria identification. In 2022, EUCAST published standardized disk diffusion method for the drug susceptibility testing of Bacteroides spp. and other 4 clinically significant anaerobes. Determining the sensitivity of anaerobes to antibiotics is important due to the increasing drug resistance in this group. Number of B. fragilis strains resistant to clindamycin and moxifloxacin is increasing. According to the published studies sensitivity to clindamycin and moxifloxacin is significantly rare and occurs in 64% and 68% of isolates and in 50.8% and 58.2% respectively. Carbapenems and metronidazole continue to be the most effective active antibiotics to be used in the empirical therapy of anaerobic bacteraemia. There are case reports of infections caused by multidrug-resistant strains of Bacteroides spp, meaning resistant to at least three antibiotics from different groups. Rapid microbial diagnosis, targeted therapy and surgical treatment of a possible source of infection are crucial in treatment of sepsis caused by anaerobic bacteria.
Bakterie Modyfikowane Genetycznie – Perspektywy Zastosowania w Profilaktyce, Diagnostyce I Terapii
Authors: Macura Barbara , Kiecka Aneta , Szczepanik Marian
Published: March 2022

Streszczenie

Prawidłowy stan mikrobioty warunkuje wiele efektów prozdrowotnych w organizmie człowieka. Zaburzenia w równowadze mikrobioty mogą być regulowane poprzez dostarczanie do organizmu probiotyków. Niestety, ich podawanie wiąże się z pewnymi ograniczeniami. Probiotyki są głównie wykorzystywane w profilaktyce wielu schorzeń, a w terapii wykazują jedynie działanie wspomagające. Ponadto probiotyki w czasie obróbki technologicznej oraz w czasie przechodzenia przez przewód pokarmowy mogą tracić swoją biologiczną aktywność. Ograniczenia te mogą zostać pokonane dzięki wprowadzeniu modyfikacji genetycznych do komórek bakteryjnych. Aktualne badania wykazują, że takie modyfikacje mogą zmienić właściwości biologiczne bakterii i znacznie rozszerzyć zakres ich wykorzystania w medycynie o właściwości diagnostyczne i terapeutyczne.
Analysis of Economic Cycles in Kondratieff’s Long Cycle Theory and in Bejan’s Constructal Theory
Authors: ISAIC Radu
Published: March 2022

Academic discourse has recently seen an increase in its attention to the emergence of a new crisis. As usual, every well-known economist, university professor and researcher attempts to make theoretical or practical arguments about how a hypothetical crisis unfolds and to identify its possible underlying causes. The desire for notoriety pushes economists to random expectations. Slightly panic-stricken, economists adept at different theoretical approaches to business cycles predict a bleak future. Several schools of economic thought have provided different explanations for crises and economic cycles (at a first count, there are about 12 more significant ones and 2-3 more secondary ones); to which we may add the explanations of historians, sociologists, etc. In economics textbooks, four names appear more frequently in the chapters on economic cycles: Kitchin, Juglar, Kuznetz and Kondratieff; and there are often explanations of cycles in the Keynesian line of thinking. Usually, the focus of the textbooks falls on Nikolai Kondratieff’s long cycles. Although the eponymous economist did not give clear explanations as to the causes of cycle production and their identification is empirical, his followers have identified this type of cycle for more than 1000 years. It therefore cannot be a mere coincidence. The question is: can we bring something new to this field? We think so. And we believe that we can explain the issues that have escaped Kondratieff, we can especially identify the causes of long cycles. How do we propose to accomplish this? The answer lies in using Professor Adrian Bejan’s Constructal Theory. This theory speaks of the economy in terms of flow systems: systems that evolve and grow to facilitate the flow as well as decrease the resistances and spread them evenly throughout the systems involved.
Acute complication after frenulotomy – case report
Authors: Wolniewicz Maria , Piotrowska Alicja , Pilch Macej , Zawadzka-Głos Lidia
Published: March 2022

The shorten lingual frenulum is the most common congenital defect of the tongue, in which the frenulum is incorrectly tied to the bottom of the oral cavity. This type of anatomy significantly reduces normal tongue movement and leads to several abnormalities, like problems with breast feeding, speech impediments, malocclusion, functional disorders, dyspnea, dysarthria, social problems. We can distinguish several methods of the treatment of this abnormality, both conservative (like exercise of the muscles of the tongue or appropriate speech therapy) and surgical, most commonly frenulotomy. Technically, the procedure of the frenulotomy is quite easy to perform, but requires proper acquaintance with the anatomy of this region determining the potential extent of the procedure and thorough investigation of our patient in order to avoid possible serious, sometimes even life-threatening, complications. In our article we present a case of a 16-year-old patient treated chronically due to malocclusion in a private dental center that was qualified for the procedure of frenulotomy after a speech therapy consultation. The procedure was performed under local anesthesia and unfortunately complicated by massive bleeding from the mouth.