bluuebunny/crossref_metadata_2025 huggingface dataset:
Low Population Differentiation but High Phenotypic Plasticity of European Beech in Germany
Authors: Müller Markus , Kempen Tanja , Finkeldey Reiner , Gailing Oliver
Published: December 2020

Drought is increasingly impairing the vitality of European beech (Fagus sylvatica L.) in several regions of its distribution range. In times of climate change, adaptive traits such as plant phenology and frost tolerance are also becoming more important. Adaptive patterns of European beech seem to be complex, as contrasting results regarding the relative effect of phenotypic plasticity and genetic variation in trait variation have been reported. Here, we used a large translocation experiment comprising more than 15,500 seedlings in three regions of Germany to investigate local adaptation and phenotypic plasticity in beech. We found low population differentiation regarding plant survival, and plant height increment, but high phenotypic plasticity for these traits. Survival showed a positive correlation with temperature variables and a less pronounced and negative correlation with precipitation-related variables. This suggests a predominant effect of temperature and growing degree days on the survival of beech seedlings under moderate drought stress. The high phenotypic plasticity may help beech to cope with changing environmental conditions, albeit increasing drought stress may make adaptive changes necessary in the long term.
Erratum: Perry, K.I., et al. Responses of Ground-Dwelling Invertebrates to Gap Formation and Accumulation of Woody Debris from Invasive Species, Wind, and Salvage Logging Running Title: Perry and Herms: Responses of Ground-Dwelling Invertebrates. Forests 2017, 8, 174
Authors: Perry Kayla I. , Herms Daniel A.
Published: December 2020

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Quantitative Genetic Variation in Bark Stripping of Pinus radiata
Authors: Nantongo Judith S. , Potts Brad M. , Fitzgerald Hugh , Newman Jessica , Elms Stephen , Aurik Don , Dungey Heidi , O’Reilly-Wapstra Julianne M.
Published: December 2020

Bark stripping by mammals is a major problem for conifer forestry worldwide. In Australia, bark stripping in the exotic plantations of Pinus radiata is mainly caused by native marsupials. As a sustainable management option, we explored the extent to which natural variation in the susceptibility of P. radiata is under genetic control and is thus amenable to genetic improvement. Bark stripping was assessed at ages four and five years in two sister trials comprising 101 and 138 open-pollinated half-sib families. A third younger trial comprising 74 full-sib control-pollinated families was assessed at two and three years after planting. Significant additive genetic variation in bark stripping was demonstrated in all trials, with narrow-sense heritability estimates between 0.06 and 0.14. Within sites, the amount of additive genetic variation detected increased with the level of bark stripping. When strongly expressed across the two sister trials, the genetic signal was stable (i.e., there was little genotype × environment interaction). No significant non-additive effect (specific combining ability effect) on bark stripping was detected in the full-sib family trial, where it was estimated that up to 22.1% reduction in bark stripping might be achieved by selecting 20% of the less susceptible families. Physical traits that were genetically correlated, and likely influenced the amount of bark removed from the trees by the marsupials, appeared to depend upon tree age. In the older trials, these traits included bark features (presence of rough bark, rough bark height, and bark thickness), whereas in the younger trial where rough bark was not developed, it was the presence of obstructive branches or needles on the stem. In the younger trial, a positive genetic correlation between prior height and bark stripping was detected, suggesting that initially faster growing trees exhibit more bark stripping than slower growing trees but later develop rough bark faster and became less susceptible. While the presence of unexplained genetic variation after accounting for these physical factors suggests that other explanatory plant traits may be involved, such as chemical traits, overall the results indicate that selection for reduced susceptibility is possible, with potential genetic gains for deployment and breeding.
Structure and Composition of Terra Firme and Seasonally Flooded Várzea Forests in the Western Brazilian Amazon
Authors: Bredin Yennie K. , Hawes Joseph E. , Peres Carlos A. , Haugaasen Torbjørn
Published: December 2020

Research Highlights: Rare, or sparsely distributed, species drive the floristic diversity of upland, terra firme and seasonally flooded forests in the central Juruá—a remote and hitherto floristically poorly known area in the Brazilian Amazon. Background and Objectives: Floristic inventories are critical for modelling and understanding the role of Amazonian forests in climate regulation, for sustainable management of forest resources and efficient conservation planning. Yet, detailed information about the often complex spatial distributions of many Amazonian woody plants is limited. Here, we provide information about forest structure and species composition from a remote terra firme forest and an adjacent floodplain forest in the western Brazilian Amazon. More specifically, we ask (1) how floristically different are the terra firme and floodplain forests? and (2) how variable is species composition within the same forest type? Materials and Methods: Between September 2016 and October 2017, we inventoried 97 plots (each 0.1 ha; 100 × 10 m) placed at least 800 m apart, with 46 plots in terra firme forest and 51 in seasonally flooded forest. We included all trees, hemi-epiphytes and palms with diameter at breast height (dbh) > 10 cm and woody lianas > 5 cm dbh. We examine forest structure, family- and species-level floristic composition and species diversity within and between forest types using family and species importance values, rarefaction curves and dissimilarity matrices. Results: Terra firme forest and seasonally flooded forest woody plant communities differ both in structure and species composition, which was highly variable within forest types. Many species were shared between terra firme and seasonally flooded forests, but most species were forest type-specific. Whereas species richness was greatest in the terra firme forest, floodplain species richness was among the highest regionally. Conclusions: Floodplain forests are a crucial complement to terra firme forests in terms of Amazonian woody plant diversity.
Changes in Proline Levels during Seed Development of Orthodox and Recalcitrant Seeds of Genus Acer in a Climate Change Scenario
Authors: Kijowska-Oberc Joanna , Staszak Aleksandra M. , Wawrzyniak Mikołaj K. , Ratajczak Ewelina
Published: December 2020

In the present study, we examined the utility of proline usage as a biochemical indicator of metabolic changes caused by climate change (mean temperature and precipitation) during seed development of two Acer species differing in desiccation tolerance: Norway maple (Acer platanoides L.—desiccation tolerant—orthodox) and sycamore (Acer pseudoplatanus L.—desiccation sensitive—recalcitrant). In plants, proline is an element of the antioxidant system, which has a role in response to water loss and high temperatures. Our study considered whether proline could be treated as an indicator of tree seed viability, crucial for genetic resources conservation. Proline content was measured biweekly in developing seeds (between 11 and 23 weeks after flowering) collected in consecutive years (2017, 2018, and 2019). We showed that proline concentrations in recalcitrant seeds were positively correlated with mean two-week temperature. In contrast, in orthodox seeds no such relationship was found. Proline content proved to be sensitive to thermal-moisture conditions changes, which makes it a promising biochemical marker of seed desiccation tolerance in different climatic conditions.
Challenges and Possibilities of ICT-Mediated Assessment in Virtual Teaching and Learning Processes
Authors: Torres-Madroñero Esperanza Milena , Torres-Madroñero Maria C. , Ruiz Botero Luz Dary
Published: December 2020

The transformations in educational environments due to the immersion of information and communication technologies (ICT) make it necessary to analyze the limits and possibilities of the assessment of the virtual training process. This paper presents an analysis of the meanings of ICT-mediated assessment, establishing what kinds of knowledge are suitable for this type of evaluation, and the challenges and possibilities of virtual tools. For this, we present a systematic review of ICT-mediated evaluation and assessment according to the educational paradigms and their implementation. We highlight that contemporary pedagogical models and their implementation in ICT mediation tools show a trend towards quantitative and summative valuation. The commonly used learning management systems (LMS) include several types of questions oriented to quantitative evaluation, with multiple-choice being the most common. However, new technological approaches like gamification, virtual reality and mobile learning open new assessment possibilities. The ICT educational platforms and new technologies demand new skills for all educational actors, such as digital literacy.
A Survey on Nonstrategic Models of Opinion Dynamics
Authors: Grabisch Michel , Rusinowska Agnieszka
Published: December 2020

The paper presents a survey on selected models of opinion dynamics. Both discrete (more precisely, binary) opinion models as well as continuous opinion models are discussed. We focus on frameworks that assume non-Bayesian updating of opinions. In the survey, a special attention is paid to modeling nonconformity (in particular, anticonformity) behavior. For the case of opinions represented by a binary variable, we recall the threshold model, the voter and q-voter models, the majority rule model, and the aggregation framework. For the case of continuous opinions, we present the DeGroot model and some of its variations, time-varying models, and bounded confidence models.
“Then Who Are You?”: Young American Indian and Alaska Native Women Navigating Cultural Connectedness in Dating and Relationships
Authors: Schultz Katie , Noyes Emma
Published: December 2020

Despite disproportionately high rates of intimate partner violence among American Indian and Alaska Native (AI/AN) women and associations between adolescent dating violence and partner violence in adulthood, little to no research has focused on dating and relationships among AI/AN adolescents. Using exploratory thematic analysis with focus group data (N = 16), we explore this topic among a sample of young AI/AN women (ages 15–17). Results suggest that dating may enhance or inhibit connections to culture or tribal identity. Moreover, responsibility for sustaining cultural knowledge, practices, and lineage may influence choices of reproductive partners for Native women living within colonial structures of governance. The greatest threat in relationships were similar to those from settler colonialism—loss of culture and consequently, self. Promoting healthy relationships among this population should include cultural safety, identity, and involvement, as well as a focus on broader systems, including enrollment policies, that may influence these relationships. Supportive networks and mentorship related to identity and cultural involvement should be available for young AI/AN women. In response to this Special Issue’s call for work that offers creative approaches to conveying knowledge and disruptions to what are considered acceptable narrative approaches we offer illustrations as well as text.
Exon-Trapping Assay Improves Clinical Interpretation of COL11A1 and COL11A2 Intronic Variants in Stickler Syndrome Type 2 and Otospondylomegaepiphyseal Dysplasia
Authors: Micale Lucia , Morlino Silvia , Schirizzi Annalisa , Agolini Emanuele , Nardella Grazia , Fusco Carmela , Castellana Stefano , Guarnieri Vito , Villa Roberta , Bedeschi Maria Francesca , Grammatico Paola , Novelli Antonio , Castori Marco
Published: December 2020

Stickler syndrome (SS) is a hereditary connective tissue disorder affecting bones, eyes, and hearing. Type 2 SS and the SS variant otospondylomegaepiphyseal dysplasia (OSMED) are caused by deleterious variants in COL11A1 and COL11A2, respectively. In both genes, available database information indicates a high rate of potentially deleterious intronic variants, but published evidence of their biological effect is usually insufficient for a definite clinical interpretation. We report four previously unpublished intronic variants in COL11A1 (c.2241 + 5G>T, c.2809 − 2A>G, c.3168 + 5G>C) and COL11A2 (c.4392 + 1G>A) identified in type 2 SS/OSMED individuals. The pathogenic effect of these variants was first predicted in silico and then investigated by an exon-trapping assay. We demonstrated that all variants can induce exon in-frame deletions, which lead to the synthesis of shorter collagen XI α1 or 2 chains. Lacking residues are located in the α-triple helical region, which has a crucial role in regulating collagen fibrillogenesis. In conclusion, this study suggests that these alternative COL11A1 and COL11A2 transcripts might result in aberrant triple helix collagen. Our approach may help to improve the diagnostic molecular pathway of COL11-related disorders.
Status of Theory Use in Self-Care Research
Authors: Jaarsma Tiny , Westland Heleen , Vellone Ercole , Freedland Kenneth E. , Schröder Carin , Trappenburg Jaap C. A. , Strömberg Anna , Riegel Barbara
Published: December 2020

Background: Theories can provide a foundation to explain behavior, investigate relationships, and to predict the effect of interventions. The aim of the study was to clarify the use of theories in studies testing interventions to promote self-care. Method: A scoping review. PubMed, EMBASE, PsychINFO, and CINAHL were searched from January 2008 through January 2019. Nine common chronic conditions were included. We included studies testing a self-care intervention if they used a randomized controlled trial design. The study was registered in PROSPERO (#123719). Results: The search retrieved 9309 potential studies, of which 233 were included in the review. In total, 76 (33%) of the 233 studies used a theory and 24 different theories were used. Bandura’s social cognitive theory was the most frequently used (48 studies), but 22 other theories were used in a minority of studies. Most studies used theories minimally to justify or provide a rationale for the study, to develop the intervention, to select outcomes, and/or to explain the results. Only eight studies fully used a theory in the rationale, intervention development, choice of outcomes, and discussion. Conclusion: The use of theories to guide self-care research is limited, which may pose a barrier in accumulating knowledge underlying self-care interventions.
The Effect of Traumatic Experiences of North Korean Adolescent Refugees upon Their Negative Health Perception: Focusing on Multiple Moderating Effect of Problem-Focused versus Social Support-Focused Coping Strategies
Authors: Ryu Wonjung
Published: December 2020

The health problems of North Korean (NK) refugees living a new life after surviving the dangers of life and death traumas is an issue that must be taken very seriously. Adolescent refugees may be particularly vulnerable to adverse physical and mental health issues because of major physical, cognitive, and psychosocial developmental changes during adolescence. This study examines the positive roles two active coping strategies—problem-focused coping and social support-focused coping—can play in NK refugee adolescents’ health self-awareness. The analysis found that “social support-focused coping” alleviates the negative relationship between traumatic experience and health perception, acting as a protective factor. Contrary to our prediction, the protective effect of adopting “problem-focused coping” in this study was not verified. The findings suggest that providing interventions for developing appropriate coping strategies help them live healthier, both physically and mentally, in South Korean society.
Acute Effects of Using Added Respiratory Dead Space Volume in a Cycling Sprint Interval Exercise Protocol: A Cross-Over Study
Authors: Danek Natalia , Michalik Kamil , Smolarek Marcin , Zatoń Marek
Published: December 2020

Background: The aim of the study was to compare acute physiological, biochemical, and perceptual responses during sprint interval exercise (SIE) with breathing through a device increasing added respiratory dead space volume (ARDSV) and without the device. Methods: The study involved 11 healthy, physically active men (mean maximal oxygen uptake: 52.6 ± 8.2 mL∙kg1∙min−1). During four visits to a laboratory with a minimum interval of 72 h, they participated in (1) an incremental test on a cycle ergometer; (2) a familiarization session; (3) and (4) cross-over SIE sessions. SIE consisted of 6 × 10-s all-out bouts with 4-min active recovery. During one of the sessions the participants breathed through a 1200-mL ARDSv (SIEARDS). Results: The work performed was significantly higher by 4.4% during SIEARDS, with no differences in the fatigue index. The mean respiratory ventilation was significantly higher by 13.2%, and the mean oxygen uptake was higher by 31.3% during SIEARDS. Respiratory muscle strength did not change after the two SIE sessions. In SIEARDS, the mean pH turned out significantly lower (7.26 vs. 7.29), and the mean HCO3– concentration was higher by 7.6%. Average La− and rating of perceived exertion (RPE) did not differ between the sessions. Conclusions: Using ARDSV during SIE provokes respiratory acidosis, causes stronger acute physiological responses, and does not increase RPE.
Determining Strategies for Constructing the Safety Supervision System by Considering Both Internal and External Safety Environments: A Case Study of X Group Corporation, China
Authors: Wang Qiaoli , Peng Xianyan , Li Zijun
Published: December 2020

Safety supervision aims to safeguard the overall interests of the corporation, and ensure its safety production together with sustainable development. It is the key to reducing accident rates, and safeguarding employees’ safety and corporate property. The establishment of safety supervision system requires specify strategies. However, it is difficult to determine such strategies in an objective manner under complex environments. Therefore, first, this paper combined an external factor evaluation matrix (EFEM) and an internal factor evaluation matrix (IFEM) to analyze the internal and external safety environments faced by X Group Corporation (XGC). Second, the strength-weakness-opportunity-threat (SWOT) approach was employed to qualitatively analyze and explore the alternative safety supervision strategies. Following this, the most attractive strategies were selected from alternatives by using the quantitative strategic planning matrix (QSPM), namely construction of the safety culture system, clarification of modes and organizational structure of safety supervision, and improvement of the safety performance evaluation system. These strategies were subsequently applied in the construction and improvement of the XGC’s safety supervision system. This study can provide reliable theoretical and methodological support for the establishment of corporations’ safety supervision systems.
Multi- and Single-Joint Resistance Exercises Promote Similar Plantar Flexor Activation in Resistance Trained Men
Authors: Gentil Paulo , Souza Daniel , Santana Murillo , Alves Rafael Ribeiro , Campos Mário Hebling , Pinto Ronei , Bottaro Martim
Published: December 2020

The present study aimed to compare soleus, lateral, and medial gastrocnemius muscles activation during leg press and calf raise exercises in trained men. The study involved 22 trained men (27.1 ± 3.6 years, 82.7 ± 6.6 kg, 177.5 ± 5.2 cm, 3.6 ± 1.4 experience years) who performed one set of each exercise using a 10-repetition maximum (10RM) load in a counterbalanced randomized order and separated by 10 min of rest. The electromyographic signal was measured for the three major plantar flexors: soleus, medial, and lateral gastrocnemius. A comparison between exercises showed that the mean adjusted by peak values during the leg press were 49.20% for the gastrocnemius lateralis, 51.31% for the gastrocnemius medialis, and 50.76% for the soleus. Values for calf raise were 50.70%, 52.19%, and 51.34% for the lateral, medial gastrocnemius, and soleus, respectively. There were no significant differences between exercises for any muscle (lateral gastrocnemius (p = 0.230), medial gastrocnemius (p = 0.668), and soleus (p = 0.535)). The present findings suggest that both leg press and calf raises can be used with the purpose to recruit triceps surae muscles. This bring the suggestion that one can chose between exercises based on personal preferences and practical aspects, without any negative impact on muscle activation.
A Transdisciplinary Analysis of COVID-19 in Italy: The Most Affected Country in Europe
Authors: Ortenzi Flaminia , Albanese Emiliano , Fadda Marta
Published: December 2020

As of 27 March 2020, 199 countries and territories and one international conveyance are affected by the COVID-19 pandemic. As of the same date, Italy represents the third country worldwide in total number of cases and the first one in total number of deaths. The purpose of this study is to analyse the Italian case and identify key problem questions and lessons learned from the Italian experience. The study initially provides a general overview of the country’s characteristics and health care system, followed by a detailed description of the Italian epidemiological picture regarding COVID-19. Afterwards, all non-pharmaceutical measures adopted by the Government against COVID-19 are presented in chronological order. The study explores some estimations of the economic impact of the epidemic, as well as its implications for society, lifestyle, and social media reactions. Finally, the study refers to two types of mathematical models to predict the evolution of the spread of COVID-19 disease. Having considered all of the above-mentioned aspects, some significant issues can be raised, including the following: (1) the available epidemiological data presents some gaps and potential biases; (2) mathematical models always come with high levels of uncertainty; (3) the high number of deaths should be interpreted in light of the national demographic context; and (4) the long-term management of the epidemic remains an open question. In conclusion, the Italian experience definitely highlights the importance of preparedness and early action, effective interventions and risk communication.
Cut-Off Values in the Prediction of Success in Olympic Distance Triathlon
Authors: Gadelha André Bonadias , Sousa Caio Victor , Sales Marcelo Magalhaes , dos Santos Rosa Thiago , Flothmann Marti , Barbosa Lucas Pinheiro , da Silva Aguiar Samuel , Olher Rafael Reis , Villiger Elias , Nikolaidis Pantelis Theodoros , Rosemann Thomas , Hill Lee , Knechtle Beat
Published: December 2020

Cut-off points and performance-related tools are needed for the development of the Olympic distance triathlon. The purposes of the present study were (i) to determine cut-off values to reach the top three positions in an Olympic distance triathlon; (ii) to identify which discipline present the highest influence on overall race performance and if it has changed over the decades. Data from 1989 to 2019 (n = 52,027) from all who have competed in an official Olympic distance triathlon events (World Triathlon Series and Olympics) were included. The cut-off value to achieve a top three position was calculated. Linear regressions were applied for performance trends overall and for the top three positions of each race. Men had cut-off values of: swimming = 19.5 min; cycling = 60.7 min; running = 34.1 min. Women’s cut-off values were: swimming = 20.7 min; cycling = 71.6 min; running = 38.1 min. The running split seemed to be the most influential in overall race time regardless of rank position or sex. In conclusion, cut-offs were established, which can increase the chances of achieving a successful rank position in an Olympic triathlon. Cycling is the discipline with the least influence on overall performance for both men and women in the Olympic distance triathlon. This influence pattern has not changed in the last three decades.
A Systematic Review of the Assessment of Support Needs in People with Intellectual and Developmental Disabilities
Authors: Verdugo Miguel A. , Aguayo Virginia , Arias Victor B. , García-Domínguez Laura
Published: December 2020

An evaluation of support needs is fundamental to the provision of services to people with intellectual and developmental disabilities. Services should be organized by considering the support that people need to improve their quality of life and enforce their rights as citizens. This systematic review is conducted to analyze the rigor and usefulness of the available standardized tools for assessing support needs, as well as the uses of their results. Several databases were consulted, including Web of Sciences, Scopus, PubMed, ProQuest Central, PsycInfo, ERIC, and CINAHL, and the 86 documents that met the review criteria were organized into four sections: (a) measurement tools, (b) descriptive/correlational studies, (c) predictive studies, and (d) interventions. The results showed that age, level of intellectual disability, adaptive behavior skills, the number and type of associated disabilities, and medical and behavioral needs affected the support needs of people with disabilities. Quality of life outcomes have been predicted by the individual’s support needs, explaining a significant percentage of their variability. The findings are useful in guiding assessments and planning interventions. Further research should address the effectiveness of specific support strategies and the development of social policies and indicators for inclusion that involve assessing support needs.
Self-Assessment Tool to Promote Organizational Health Literacy in Primary Care Settings in Switzerland
Authors: De Gani Saskia Maria , Nowak-Flück Daniela , Nicca Dunja , Vogt Dominique
Published: December 2020

Dealing with health information and taking care of one’s own health are key aspects of health literacy and a difficulty for nearly half of the population in Europe. Limited health literacy often results in poorer health outcomes. Health literacy is a fundamental health determinant, and its improvement provides great potential for addressing public health challenges. Health care organizations play an important role in improving population’s health literacy. Health literate health care organizations facilitate access, understanding and use of health information and decrease the demands and complexities of the health care system. Few efforts have been taken so far to promote organizational health literacy, especially in German-speaking countries. This project aimed at developing a self-assessment tool, which enables primary care organizations to assess and improve their level of health literacy. The self-assessment tool was developed and evaluated with general practitioners and community care organizations in Switzerland. Here the participative development process, outcomes and the three modules of the self-assessment tool are presented: (1) manual with detailed introduction and instruction, (2) checklist for self-assessment of organizational health literacy and (3) handbook with measures for improvement. The aim of this tool is that organizations are able to identify the need for action, plan and implement improvement measures.
Geographic Differences in Lung Cancer Incidence: A Study of a Major Metropolitan Area within Southeastern Pennsylvania
Authors: Zhu Yaqian , McKeon Thomas P. , Tam Vicky , Vachani Anil , Penning Trevor M. , Hwang Wei-Ting
Published: December 2020

This study investigated the geographic variation and the clustering of lung cancer incidence rates in Philadelphia and the surrounding areas using addresses at the time of diagnosis. Using 60,844 cases from Pennsylvania Cancer Registry, we calculated and mapped the age-adjusted incidence rates for five Pennsylvania (PA) counties near Philadelphia between 1998–2007 and 2008–2017. We identified ZIP codes with significantly higher incidence rates than the state rates and examined their demographic and exposure characteristics. Further, we tested for spatial autocorrelation and identified spatial clusters using Moran’s I statistic. Our results showed that approximately one in four ZIP codes had an incidence rate that was significantly higher than the PA state rate in each period studied. Clusters of higher incidences were detected in the southeastern part of PA bordering New Jersey. These areas tended to be more populated, of lower socioeconomic status, and closer to manufacturing facilities and major highways. Possibly driven by the community and environmental factors, the observed differences in disease incidence suggest the importance of including residential location in risk assessment tools for lung cancer.
Batch and Fixed-Bed Column Studies on Palladium Recovery from Acidic Solution by Modified MgSiO3
Authors: Vancea Cosmin , Mihailescu Maria , Negrea Adina , Mosoarca Giannin , Ciopec Mihaela , Duteanu Narcis , Negrea Petru , Minzatu Vasile
Published: December 2020

Effective recovery of palladium ions from acidic waste solutions is important due to palladium’s intensive usage as a catalyst for different industrial processes and to the high price paid for its production from natural resources. In this paper, we test the ability of a new adsorbent, MgSiO3 functionalized by impregnation with DL-cysteine (cys), for palladium ion recovery from waste solutions. The Brunauer–Emmett–Teller (BET) surface area analysis, Barrett–Joyner–Halenda (BJH) pore size and volume analysis, scanning electron microscopy (SEM), energy dispersive X-ray (EDX) spectroscopy and Fourier-Transformed Infrared (FTIR) spectroscopy have been performed to characterize this material. Firstly, the maximum adsorption capacity of the new obtained material, MgSiO3-cys, in batch, was studied. To establish the adsorption mechanism, the obtained experimental data were fitted using the Langmuir, Freundlich and Sips adsorption isotherms. Studies on the adsorption of palladium ions on the synthesized material were performed in a dynamic regime, in a fixed-bed column. The Pd(II) recovery mechanism in the dynamic column regime was established based on Bohart–Adams, Yoon–Nelson, Thomas, and Clark models. The obtained equilibrium adsorption capacity was 9.3 (mg g−1) in static regime (batch) and 3 (mg g−1) in dynamic regime (column). The models that best describe the Pd(II) recovery process for batch and column adsorption are Sips and Clark, respectively.
Invasive Coronary Angiography after Chest Pain Presentations to Emergency Departments
Authors: Sanfilippo Frank M. , Hillis Graham S. , Rankin Jamie M. , Latchem Donald , Schultz Carl J. , Yong Jongsay , Li Ian W. , Briffa Tom G.
Published: December 2020

We investigated patients presenting to emergency departments (EDs) with chest pain to identify factors that influence the use of invasive coronary angiography (ICA). Using linked ED, hospitalisations, death and cardiac biomarker data, we identified people aged 20 years and over who presented with chest pain to tertiary public hospital EDs in Western Australia from 1 January 2016 to 31 March 2017 (ED chest pain cohort). We report patient characteristics, ED discharge diagnosis, pathways to ICA, ICA within 90 days, troponin test results, and gender differences. Associations were examined with the Pearson Chi-squared test and multivariate logistic regression. There were 16,974 people in the ED chest pain cohort, with a mean age of 55.6 years and 50.7% males, accounting for 20,131 ED presentations. Acute coronary syndrome was the ED discharge diagnosis in 10.4% of presentations. ED pathways were: discharged home (57.5%); hospitalisation (41.7%); interhospital transfer (0.4%); and died in ED (0.03%)/inpatients (0.3%). There were 1546 (9.1%) ICAs performed within 90 days of the first ED chest pain visit, of which 59 visits (3.8%) had no troponin tests and 565 visits (36.6%) had normal troponin. ICAs were performed in more men than women (12.3% vs. 6.1%, p < 0.0001; adjusted OR 1.89, 95% CI 1.65, 2.18), and mostly within 7 days. Equal numbers of males and females present with chest pain to tertiary hospital EDs, but men are twice as likely to get ICA. Over one-third of ICAs occur in those with normal troponin levels, indicating that further investigation is required to determine risk profile, outcomes and cost effectiveness.
Time Series Analysis of Climate and Air Pollution Factors Associated with Atmospheric Nitrogen Dioxide Concentration in Japan
Authors: Miyama Takeshi , Matsui Hiroshi , Azuma Kenichi , Minejima Chika , Itano Yasuyuki , Takenaka Norimichi , Ohyama Masayuki
Published: December 2020

Nitrogen dioxide (NO2) is an air pollutant discharged from combustion of human activities. Nitrous acid (HONO), measured as NO2, is thought to impact respiratory function more than NO2. HONO and NO2 have an equilibrium relationship, and their reaction is affected by climate conditions. This study was conducted to discuss the extent of HONO contained in NO2, depending on the level of urbanization. Whether climate conditions that promote HONO production enhanced the level of NO2 measured was investigated using time series analysis. Climate and outdoor air pollution data measured in April 2009–March 2017 in urban (Tokyo, Osaka, and Aichi) and rural (Yamanashi) areas in Japan were used for the analysis. Air temperature had a trend of negative associations with NO2, which might indicate the decomposition of HONO in the equilibrium between HONO and NO2. The associations of relative humidity with NO2 did not have consistent trends by prefecture: humidity only in Yamanashi was positively associated with NO2. In high relative humidity conditions, the equilibrium goes towards HONO production, which was observed in Yamanashi, suggesting the proportion of HONO in NO2 might be low/high in urban/rural areas.
Feasibility of Indonesia Family Life Survey Wave 5 (IFLS5) Data for Air Pollution Exposure–Response Study in Indonesia
Authors: Agustian Dwi , Rachmi Cut Novianti , Indraswari Noormarina , Molter Anna , Carder Melanie , Rinawan Fedri Ruluwedrata , van Tongeren Martie , Driejana Driejana
Published: December 2020

Background: Air pollution is an important risk factor for the disease burden; however there is limited evidence in Indonesia on the effect of air pollution on health, due to lack of exposure and health outcome data. The objective of this study is to evaluate the potential use of the IFLS data for response part of urban-scale air pollution exposure–health response studies. Methods: Relevant variables were extracted based on IFLS5 documentation review. Analysis of the spatial distribution of respondent, data completeness, prevalence of relevant health outcomes, and consistency or agreement evaluation between similar variables were performed. Power for ideal sample size was estimated. Results: There were 58,304 respondents across 23 provinces, with the highest density in Jakarta (750/district). Among chronic conditions, hypertension had the highest prevalence (15–25%) with data completeness of 79–83%. Consistency among self-reported health outcome variables was 90–99%, while that with objective measurements was 42–70%. The estimated statistical power for studying air pollution effect on hypertension (prevalence = 17%) in Jakarta was approximately 0.6 (α = 0.1). Conclusions: IFLS5 data has potential use for epidemiological study of air pollution and health outcomes such as hypertension, to be coupled with high quality urban-scale air pollution exposure estimates, particularly in Jakarta.
Cardiorespiratory, Metabolic and Muscular Responses during a Video-Recorded Aerobic Dance Session on an Air Dissipation Platform
Authors: Moreira-Reis Alessandra , Maté-Muñoz José Luis , Hernández-Lougedo Juan , García-Fernández Pablo , Pleguezuelos-Cobo Eulogio , Carbonell Teresa , Alva Norma , Garnacho-Castaño Manuel Vicente
Published: December 2020

Background: Aerobic dance (AD) is an appropriate physical activity for improving cardiorespiratory fitness. This study aimed to compare cardiorespiratory and metabolic responses, and muscle fatigue between an air dissipation platform (ADP) and a hard surface during a video-recorded AD session. Methods: 25 healthy young women (23.3 ± 2.5 years) completed three sessions. In session 1, participants performed an incremental test to exhaustion on a treadmill. One week after session 1, participants were randomly assigned in a crossover design to perform video-recorded AD sessions on an ADP and on a hard surface (sessions 2 and 3). Cardiorespiratory and metabolic responses were assessed during AD sessions. Muscular fatigue was measured before and after AD sessions by a countermovement jump test. Results: Significantly higher heart rate, respiratory exchange ratio, pulmonary ventilation, ventilatory oxygen equivalent, and ventilatory carbon dioxide equivalent were observed on an ADP than on a hard surface (p < 0.05). Despite a significant increase in lactate levels on an ADP (p ≤ 0.01), muscular fatigue and perceived exertion rating were similar on both surfaces (p > 0.05). Conclusions: Video-recorded AD on an ADP increased the cardioventilatory and metabolic responses compared to a hard surface, preventing further muscle fatigue.
Real World Use of Antidiabetic Drugs in the Years 2011–2017: A Population-Based Study from Southern Italy
Authors: Ingrasciotta Ylenia , Bertuccio Maria Paola , Crisafulli Salvatore , Ientile Valentina , Muscianisi Marco , L’Abbate Luca , Pastorello Maurizio , Provenzano Vincenzo , Scorsone Alessandro , Scondotto Salvatore , Trifirò Gianluca
Published: December 2020

Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia. The availability of new antidiabetic drugs (ADs) has led to complex treatment patterns and to changes in the patterns of specific drug utilization. The aim of this population-based study was to describe the pattern of antidiabetic drugs (ADs) use in Southern Italy in the years 2011–2017, in relation to the updated type 2 diabetes mellitus (T2DM) therapy guidelines. A retrospective cohort study was conducted on T2DM patients using data from the Palermo Local Health Unit (LHU) claims database and diabetologist registry. The first-line treatment was investigated and incident treatments were identified and characterized at baseline in terms of demographics, complications, comorbidities, concomitant drugs and clinical parameters. Persistence to AD treatment was also evaluated. During the study period, one-third of first ever ADs users started the treatment with ADs other than metformin, in contrast to guideline recommendations. Among 151,711 incident AD treatments, the male to female ratio was 1.0 and the median age was 66 (57–75) years. More than half (55.0%) of incident treatments discontinued the therapy during the first year of treatment. In Italy, general practitioners (GPs) can only prescribe first-generation ADs, while the prescription of more recently marketed ADs, such as GLP-1RA, DPP4i and SGLT2i, is restricted to diabetologists only, based on a therapeutic plan. The role of GPs in the management of T2DM in Italy should be re-evaluated.
Comparative Study of Hydrochemical Classification Based on Different Hierarchical Cluster Analysis Methods
Authors: Bu Jianwei , Liu Wei , Pan Zhao , Ling Kang
Published: December 2020

Traditional methods for hydrochemical analyses are effective but less diversified, and are constrained to limited objects and conditions. Given their poor accuracy and reliability, they are often used in complement or combined with other methods to solve practical problems. Cluster analysis is a multivariate statistical technique that extracts useful information from complex data. It provides new ideas and approaches to hydrogeochemical analysis, especially for groundwater hydrochemical classification. Hierarchical cluster analysis is the most widely used method in cluster analysis. This study compared the advantages and disadvantages of six hierarchical cluster analysis methods and analyzed their objects, conditions, and scope of application. The six methods are: The single linkage, complete linkage, median linkage, centroid linkage, average linkage (including between-group linkage and within-group linkage), and Ward’s minimum-variance. Results showed that single linkage and complete linkage are unsuitable for complex practical conditions. Median and centroid linkages likely cause reversals in dendrograms. Average linkage is generally suitable for classification tasks with multiple samples and big data. However, Ward’s minimum-variance achieved better results for fewer samples and variables.
Oral Microbiome Signatures in Hematological Cancers Reveal Predominance of Actinomyces and Rothia Species
Authors: Mougeot Jean-Luc C. , Beckman Micaela F. , Langdon Holden C. , Brennan Michael T. , Bahrani Mougeot Farah
Published: December 2020

The endogenous microbiome of healthy individuals in oral cavities is diverse, representing over 700 bacterial species. Imbalance in oral and gut microbiome composition and associated gene expression has been linked to different forms of hematological (blood) cancers. Our objective is to compare oral microbiome profiles of patients with blood cancers (BC group: N = 39 patients, n = 124 oral samples) to those of healthy control subjects (HC group: N = 27 subjects, n = 100 oral samples). Saliva samples and swabs of buccal mucosa, supragingival plaque, and tongue were collected from blood cancer patients and healthy controls. Next-generation sequencing (16S-rRNA gene V3–V4 region) was used to determine the relative abundance of bacterial taxa present at the genus and species levels. Differences in oral microbiome beta-diversity were determined using multivariate permutational analysis of variance (PERMANOVA). Linear discriminant analysis (LDA) effect size (LEfSe) analysis was performed to identify differentiating bacterial taxa in pairwise comparisons. The PATRICv3.6.7 online tool was used to determine the predominance of potential pathogenicity in the BC group. The oral microbiome beta-diversities of the BC and HC groups differed and corresponded to a reduced alpha-diversity in the BC group. LEfSe analysis showed significant LDA scores for Actinomyces and Rothia spp., differentiating the BC group from the HC group. In silico analysis using PATRICv3.6.7 demonstrated that the groups of bacteria possessing traits of “antibiotic resistance”, “oral pathogen”, and “virulence” was enriched in the BC group. Although 56% of the BC patients received antibiotics within two weeks of the oral bacterial sampling, Actinomyces genus remained the top differentiating feature in the BC group regardless of the administration of antibiotics, while Rothia dentocariosa was detected as the top differentiating feature in the BC patients who did not receive antibiotics, but not in those who received antibiotics. Further investigation is needed to better understand the interactions of certain oral species with the host immune system to better characterize clinically relevant associations with hematological cancers.
Prevalence of Low Energy Availability in Collegiate Women Soccer Athletes
Authors: Magee Meghan K. , Lockard Brittanie L. , Zabriskie Hannah A. , Schaefer Alexis Q. , Luedke Joel A. , Erickson Jacob L. , Jones Margaret T. , Jagim Andrew R.
Published: December 2020

(1) Background: Limited information exists on the prevalence of low energy availability (LEA) in collegiate team sports. The purpose of this study was to examine the prevalence of LEA in collegiate women soccer players. (2) Methods: Collegiate women soccer athletes (n = 18, height: 1.67 ± 0.05 m; body mass: 65.3 ± 7.9 kg; body fat %: 24.9 ± 5.6%) had their body composition and sport nutrition knowledge assessed in the pre-season. Energy availability was assessed mid-season using a 4-day dietary log and activity energy expenditure values from a team-based monitoring system. A validated screening tool was used to screen for LEA. (3) Results: The screening tool classified 56.3% of athletes as at risk of LEA (<30 kcal/kg of FFM); however, the actual dietary intake identified 67% as LEA. Athletes identified as non-LEA consumed significantly more absolute (p = 0.040) and relative (p = 0.004) energy than LEA athletes. (4) Conclusions: There was a high prevalence of LEA among collegiate women soccer athletes. Although previously validated in women endurance athletes, the LEA screening tool was not effective in identifying those at risk of LEA in this sample of athletes.
The Wear on Roller Press Rollers Made of 20Cr4/1.7027 Steel under Conditions of Copper Concentrate Briquetting
Authors: Bembenek Michał , Krawczyk Janusz , Pańcikiewicz Krzysztof
Published: December 2020

This paper defines the wear process of rollers made of 20Cr4. Rollers with a diameter of 1000 mm were installed in a roller press used for the production of drop-shaped briquettes and the copper concentrate was briquetted for 1100 h. Three-dimensional (3D) geometry analysis, metallographic analysis, macroscopy, scanning electron microscopy, as well as hardness measurements were performed. It was observed that the working surface was non-uniformly worn. The smallest wear affects the molding cavities situated on the outermost edges of the ring. The wear increases as the center of the ring is approximated, and it reaches its maximum at the middle of the ring. The molding cavities also wear asymmetrically. For the shape considered in this study, the lower part of a cavity is subject to a higher wear rate. We found that the material of the working ring was carburized, but its hardness was significantly lower than required. The roller ring microstructure changes depended on the distance from the cavity’s face. An investigation of the wear mechanisms showed different types of abrasive wear, corrosive processes, and plastic deformation. The exact type and course of wear were described, depending on the location on the working surface.
Experimental Investigation of Methyl Methacrylate in Stirred Batch Emulsion Reactor: AGET ATRP Approach
Authors: Awad Mohammed , Duever Thomas , Dhib Ramdhane
Published: December 2020

This study examines the ab initio emulsion atom transfer radical polymerization (ATRP) initiated by an eco-friendly reducing agent to produce poly(methyl methacrylate) (PMMA) polymer with controlled characteristics in a 2 L stirred batch reactor. The effect of the reaction temperature, surfactant concentration, monomer to water ratio, and stirring speed was thoroughly investigated. The results showed that PMMA coagulation becomes quite severe at a certain temperature threshold. However, the coagulation could be avoided at mild reaction temperature, since the outcomes showed that loading more surfactant to the system under high mixing speed has balanced the polymer mixture and yielded high monomer conversion. The PMMA product was analyzed by gravimetry and GPC measurements and after 5 h of polymerization at a reaction temperature of 50 °C, monomer conversion of 64.1% was obtained, and PMMA polymer samples produced had an average molar mass of 4.5 kg/mol and a polydispersity index of 1.17. The structure of the PMMA polymer was successfully proved by FTIR and nuclear magnetic resonance (NMR) spectroscopy. The results confirm the living feature of MMA AGET ATRP in emulsion medium and recommend further investigation for other types of surfactant.