bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of gene expression hypoxia-inducible factor-1a and serum level monocyte chemoattractant protein-1 in the incidence of chronic myeloid leukemia in Iraqi patients
Authors: Naeem Noor Tariq , Alsaadi Basima Qasim Hasan
Published: March 2024

BACKGROUND:

Chronic myeloid leukemia (CML) is a hematopoietic stem cell malignancy described by a translocation between chromosomes 9 and 22. There are many factors genetic or nongenetic effect on disease progression such as growth factors and transcription factors act as oncogenes or tumor suppressor genes.

OBJECTIVES:

The purpose of this research was to investigate the role of hypoxia-inducible factor (HIF1A) gene expression with CML, as well as the role of monocyte chemoattractant protein-1 (MCP-1) as a predictive biomarker on disease progression.

MATERIALS AND METHODS:

The current study consists of three groups: first group includes 50 newly diagnosed CML patients (females 22 and males 28), second group consists of 50 CML patients treated with tyrosine kinase inhibitor (TKI) with a complete molecular response (p210 BCR-ABL transcript levels ≤0.1% IS) (female 25 and male 25), and third group included another 50 apparently healthy volunteers (female 20 and male 30). The patients were admitted from the National Center of Hematology/Mustansiriyah University. All patients are diagnosed according to a complete blood count (CBC), a bone marrow examination, and a BCR-ABL gene test.

RESULTS:

Reverse transcription-quantitative polymerase chain reaction was applied to assess the expression levels of the HIF-1A gene and serum level of MCP1 by enzyme-linked immunosorbent assay. The results displayed downregulated of the HIF1A gene messenger RNA in CML patients in comparison to the controls group, as well as no statistically significant link was discovered when the fold of expression was correlated with the age and gender of CML patients.

CONCLUSION:

HIF1-alpha gene has an important role in pathological pathways such as angiogenesis. According to this study, HIF1-alpha gene is not an appropriate prognostic biomarker for detecting the risk of CML as well as MCP1 is thought to be a predictor of CML progression.
Comparative Analysis of Hemispherotomy in Adults versus Children- A Prospective Observational Series
Authors: Bajaj Jitin , Chandra Sarat P , Ramanujam Bhargavi , Subianto Heri , Girishan Shabari , Doddamani Ramesh , Agrawal Mohit , Samala Raghu , Dwivedi Rekha , Chaudhary Kapil , Garg Ajay , Tripathi Madhavi , Bal CS , Nehra Ashima , Sharma Mehar C , Tripathi Manjari
Published: March 2024

Background:

Hemispherotomy (HS) is an effective treatment for unilateral hemispheric onset epilepsy. There are few publications for HS in adults, and there is no series comparing adults and pediatric patients of HS.

Objective:

To compare the hemispherotomies done in adult patients with pediatric ones in terms of efficacy and safety.

Methods:

Data was prospectively collected for HS patients (up to 18 years and more) from Aug 2014 to Aug 2018. Comparison between the groups was made for seizure onset, duration of epilepsy, frequency of seizures, number of drugs, intraoperative blood loss, postoperative seizure control, postoperative stay, postoperative motor functions, and preoperative and postoperative intelligence quotient. Follow-up was one year.

Results:

A total of 61 pediatric and 11 adults underwent HS. The seizure onset was earlier in children, and the duration of epilepsy was longer in adults. The frequency of seizures per day was more in children being 14.62 ± 26.34 in children, and 7.71 ± 5.21 per day in adults (P - 0.49). The mean number of drugs was similar in the preoperative and postoperative periods in both. Class I seizure outcome was similar in both the groups being 85.24% in children and 90.9% in adults (P - 0.56). Blood loss, postoperative stay, was similar in both the groups. No patient had a new permanent motor deficit. Power worsened transiently in 1 pediatric patient and in 4 adult patients. The visual word reading and object naming improved in both the groups (no intergroup difference), and IQ remained the same in both groups. One adult patient had meningitis, and another had hydrocephalus requiring shunt placement.

Conclusion:

Hemispherotomy is a safe and effective procedure in adults as in children in appropriately selected patients.
Dural Venous Sinus Cyst: Clinical and Imaging Findings
Authors: Ökçesiz İzzet , Gökçe Mehmet , Dönmez Halil , Küçük Ahmet
Published: March 2024

Dural venous sinus cysts are very infrequent lesions, generally asymptomatic and incidental. These cystic lesions may include venous structures continuing with superficial cortical veins. A 23-year-old male patient presented with a severe headache. Cranial computed tomography and contrast-enhanced magnetic resonance imaging demonstrated a well-defined, central curvilinear enhanced lesion, located in the superior sagittal sinus which was compatible with the intraluminal dural venous cyst. The patient was included imaging follow-up for possible growth of this cystic lesion. Dural venous sinus cysts are asymptomatic lesions by far. However, these incidental lesions should be followed up just in case the progression-occlusion of the dural sinus. Possible venous components that may have connections with cortical veins should be considered in terms of surgery.
Indian Neurosurgeons at the Forefront: A Comprehensive Exploration of their Pioneering Contributions to Neuroendoscopy
Authors: Kodeeswaran Omsaran , Bajaj Jitin , Priyadharshan KP , Kodeeswaran M
Published: March 2024

This article delves into the profound impact of Indian neurosurgeons on the expansive canvas of neuroendoscopy. By scrutinizing their trailblazing research, innovations, new surgical techniques, and relentless dedication to education and training, we aim to unravel the intricacies of their influence on a global scale. The review, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, conducts a comprehensive analysis of the literature related to neuroendoscopy contributed by Indian neurosurgeons. The exploration covers a spectrum of achievements, ranging from pioneering research and innovations to complication avoidance, neuroendoscopic training, and global recognition. Despite challenges, Indian neurosurgeons continue to lead the way in shaping the future of neuroendoscopy, ensuring better patient outcomes and improved quality of life. Many Indian neurosurgeons have contributed significantly to the development of neuroendoscopy in India. Prof. YR Yadav’s contributions stand significant in the form of research articles and publications on almost all subjects on neuroendoscopy, the textbook on neuroendoscopy, popularizing neuroendoscopy by starting the first university-certified neuroendoscopy fellowship training program in India, describing many innovative techniques/first report of endoscopic techniques and conducting regular endoscopic workshops in his institutions and other major cities of India.
Red Cell Distribution Width is Related to Mild Cognitive Impairment: A Cross-Sectional Study of Community Residents
Authors: Yang Juan , Sui Haijing , Song Haihan , Jiao Ronghong , Zhao Xiaohui
Published: March 2024

Background and Objective:

Previous literature has reported that red cell distribution width (RDW) correlated with Alzheimer’s disease (AD), but the correlation with mild cognitive impairment (MCI) was not clear. This study aimed to investigate MCI in the residents aged ≥65 living in the suburban of Shanghai, China.

Materials and Methods:

A total of 550 participants were recruited as MCI (MCI group, 226) and normal (NC group, 284) groups and received blood examination voluntarily. Blood routine indexes were tested by blood tests using Sysmex XT-4000i (Japan). The Chi-square test, t-test, and linear regression analysis were used to find the statistical difference and correlation of data, respectively.

Results:

Each cognition domain of MCI was found to be impaired, the weight of which, however, was different in integral damage. Most MCI people had impairment of attention among cognitive domains (235, 88.3%). According to the results of the binary logistic regression, the highest weight among impaired cognitive domains was for attention in MCI, and the Wald value of attention was higher than those of others (Wald = 51.83). Additionally, RDW had the greatest negative correlation with attention score (P < 0.05).

Conclusions:

Increased RDW may be considered as a biomarker of MCI.
Giant Aneurysms: Not So Giant in Behavior
Authors: Datta Parthasarathi , Mukherjee Shuvankar , Mukherjee Anindya , Debnath Ashis , Pathak Debojyoti , Pawha Nakul
Published: March 2024

Background:

Giant intracranial aneurysms (GIAs) are very complex in their behavior and treatment procedure. There are various modalities of treatment. The annual rupture rate of GIA (6%) is higher than that of small aneurysms (1–3%). Neurosurgeons handle these aneurysms during operations.

Objective:

We tried to analyze the intraoperative rupture rate (IRR) of GIA in relation to small aneurysms. IRR is concerned with the rupture of the aneurysms during operative handling.

Materials and Methods:

For conducting the study, we compared the IRR of 7 GIAs and 45 small aneurysms during a span of 10 years. All the operations were performed by the same team and the same principal surgeon. IRR was compared by statistical analysis.

Result:

Z-test was done to compare the two rates: Z = 0.68 and P = 0.49. According to our study, the IRR of GIA is not statistically different from small aneurysms. The IRR of GIA is not higher because of three factors which we have analyzed: 1) layers of intraaneurysmal thrombus, 2) fibrin deposition on the aneurysm wall, and 3) blocked neck of the aneurysm by thrombus.

Conclusion:

The IRR of GIA is not different from small aneurysms.
Smart Assist System Module for Paralysed Patient Using IoT Application
Authors: Kishore Kanna R , Pradhan Nihar Ranjan , Panigrahi Bhawani Sankar , Basa Santi Swarup , Mohanty Sarita
Published: March 2024

Those who are hearing impaired or hard of hearing face the most difficult challenges as a result of their handicap. To establish a bond or commit to something, people should be able to express their ideas and feelings via open channels of communication. To solve such issues, simple, transportable, and accurate assistive technology will probably be developed. The glove with sensors and an Arduino microcontroller is the major focus. This system was developed specifically to translate sign languages while analyzing gesture locations using smart technologies in custom gloves. The micro-controller identifies certain hand motions using sensors attached to gloves and converts sensor output data into text. Their capacity to converse may be aided by their ability to read the text on the mobile IOT application. Also, it aids in automating the houses of people with paralysis. It has the capacity to assess biological indicators like pulse and temperature as a patient monitoring device. The system will be put into place with the intention of enhancing the quality of life for people with disabilities and providing additional assistance in bridging the communication gap. It has a low price tag and a small design.
Verification and Validation of Model-Based Systems Requirements and Design Leveraging Formal Methods to Increase Development Assurance
Authors: McMillan Craig , Lee Lawrence , Russell Daniel , Prince Daniel , Hasanovic Nihad , Durling Michael , Siu Kit , Varanasi Sarat Chandra , Meng Baoluo , Kleven Everett
Published: March 2024

As model-based systems engineering is proliferating throughout the aerospace industry as a method to manage the development of complex cyber-physical systems, opportunities to leverage formal methods for verification and validation purposes are significant. As a system model described in SysML can contain the level of semantics required to define strict system requirements, it is possible to create a translation tool to generate SRL (SADL (Semantic Application Design Language) Requirements Language) to leverage ASSERT™ (Analysis of Semantic Specifications and Efficient generation of requirements-based Tests) for verification and validation of the system requirements. SADL [13] is a controlled English grammar that translates directly into OWL (Web Ontology Language) [14]. As part of the validation of the SRL requirements, ASSERT™ leverages a theorem prover to look for conflict and completeness errors. For verification, ASSERT™ uses a Satisfiability Modulo Theories (SMT) solver for the generation of test cases and procedures. This paper extends the Braking System Control Unit (BSCU) portion of the Wheel Braking System (WBS) example within Appendix E of ARP4754B [2] described in [1] to demonstrate an example of capturing system requirements in Cameo using SysML, creating test cases and procedures from ASSERT™ exporting from SysML and translating to SRL/SADL, and exporting the Cameo system model data along with the test cases, test procedures, and requirements analysis data from ASSERT™ into the Rapid Assurance Curation Kit (RACK). RACK is a data curation platform which facilitates reporting on Development Assurance and safety assessments guidelines like those used for aircraft certification.
Path Following Performance Analysis for Siemens 840 D sl Controlled Robotic Machining Platforms with Secondary Encoders
Authors: Sawyer Daniela , Scraggs Chris
Published: March 2024

Robotic arms are widely known to fall short in achieving the tolerances required when it comes to the metal machining industry, especially for the aerospace sector. Broadly speaking, two of the main reasons for that are a lack of stiffness and a lack of accuracy. Robotic arm manufacturers have responded to the lack of stiffness challenge by producing bigger robots, capable of holding high payloads (e.g., Fanuc M-2000iA/2300) or symmetric robots (e.g., ABB IRB6660). Previous research proved that depending on the application and the material being machined, lack of stiffness will still be an issue, even for structurally bigger robotic arms, due to their serial nature. The accuracy issue has been addressed to a certain extent by using secondary encoders on the robotic arm joints. The encoder enhanced robotic arm solutions tend to be expensive and prior knowledge proves that there are still limitations when it comes to achieved accuracy. The current work aims to provide a performance analysis of the path following capabilities of two robotic machining platforms, namely the Accurate Robotic Milling System (ARMS) and the MABI MAX-100-2.25P. Both platforms are equipped with secondary encoders (optical and inductive, respectively) and Siemens 840 D sl controllers and have been designed to be used in machining applications. The performance analysis will be demonstrated with a novel path that takes into consideration the BS EN ISO 9283:1998 standards for manipulating industrial robots while utilizing machining specific feed rates and feasible working volumes for both platforms. Furthermore, an accuracy study is performed for the 840 D sl controller Sinumerik Trace tool capabilities and verified by using a Leica Absolute AT960 laser tracker to assess its reliability for usage in accuracy analysis. This would remove the need to use expensive external metrology equipment for tracking path accuracy.
Investigation of Mechanical Properties and Weld nugget Characteristics of Thermoplastics by Using Friction Stir Welding with Heat Assisted Induction Coil
Authors: Raju Ganga , Chinnakurli Suryanarayana Ramesh , Srivastava Ashish
Published: March 2024

Friction stir welding (FSW) is a method of welding that creates a weld trail by pressing a non-consumable rotating tool with a profiled pin on the adjacent surfaces while moving transversely along the welding direction. The method was initially used with metals and alloys, but more recently, thermoplastic polymers have also been included in its application. Investigations on FSW of thermoplastic polymers made of nylon and High-density polythene (HDPE) are presented here. Weld characteristics that are like those of the base materials are attempted to be achieved. Because of their unique nature and thermal conductivity, thermoplastics FSW differs from that of metals. The use of thermoplastic materials with conventional FSW procedures presents numerous difficulties and is currently ineffective. On the weld characteristics of nylon and HDPE, statistical methods were utilized to study the impact of temperature, rotational speed, and transverse speed. Temperature is found to be the most important factor, followed by rotational and traversal speeds. In general, a higher temperature in combination with lower transverse speeds produced the most desirable results. Nylon exhibited a higher UTS of 35MPa when compared with HDPE which possess UTS of 16.7 MPa after friction stir welding under optimized process parameters with using induction assisted coil. A welding efficiency of 55% and 41% were observed for nylon and HDPE respectively based on their base material UTS. Microstructural aspects will also be discussed.
Integrating MIL-STD Requirements into SysML Projects: A Unified Approach
Authors: Watson Paul
Published: March 2024

In support of developing complex systems, integrating requirements from various source standards, such as the Military Standard (MIL-STD) series and others, presents a significant challenge. This paper explores the development of Model-Based System Engineering (MBSE) Systems Modeling Language (SysML) projects that incorporate MIL-STD requirements. The study begins by defining the critical need for integrating multiple standards into MBSE projects, emphasizing the importance of adhering to MIL-STD requirements when invoked by the customer. The study further defines the limitations inherent in managing standards independently and propose a unified approach within a SysML-based framework. The research introduces a systematic methodology for mapping MIL-STD requirements and other relevant standards onto SysML constructs, ensuring traceability and consistency throughout the system development lifecycle. Comparing traditional methods with the use of MBSE methods highlight the advantages of an integrated approach in terms of reducing redundancy, enhancing traceability, and improving overall system development efficiency. In conclusion, this research paper asserts that a comprehensive methodology for encompassing MIL-STD requirements and constraining data in new MBSE SysML projects is the recommended approach. This approach bridges the gap between complex standards and system development, promoting efficiency, compliance, and traceability. It serves as a valuable resource for engineers, project managers, and organizations engaged in the development of systems requiring compliance with MIL-STDs.
Transforming AADL Models Into SysML 2.0: Insights and Recommendations
Authors: Litwin Kyle , Amundson Isaac , Verma Dinesh , McDermott Tom
Published: March 2024

In recent years, the increasing complexity of modern aerospace systems has driven the rapid adoption of robust Model-Based Systems Engineering (MBSE). MBSE is a development methodology centered around computational models, which are instrumental in supporting the design and analysis of intricate systems. In this context, the Architecture Analysis and Design Language (AADL) and Systems Modeling Language (SysML) are two prominent modeling languages for specifying and analyzing the structure and behavior of a cyber-physical system. Both languages have their own specific use cases and tool environments and are typically employed to model different aspects of system design. Although multiple software tools are available for transforming models from one language to another, their effectiveness is limited by fundamental differences in the semantics of each language. The upcoming release of SysML Version 2 provides an opportunity to address these shortcomings thanks to several improvements that bring the two languages closer together. In this paper, we embark on an exploration of a transformation pathway between AADL and SysML v2, while identifying the existing gaps and challenges that persist. Furthermore, we provide recommendations to overcome these issues. Our approach's feasibility is demonstrated using an open-source AADL model employed in a Defense Advanced Research Projects Agency (DARPA) research project as a case study. We also outline several transformation rules required for converting the AADL model into a syntactically correct and semantically equivalent SysML v2 model.
Estimated Mechanical Properties and Machinability of Steel Bars
Authors:   Metals Technical Committee
Published: March 2024

This SAE Information Report is intended to provide a guide to mechanical and machinability characteristics of some SAE steel grades. The ratings and properties shown are provided as general information and not as requirements for specifications unless each instance is approved by the source of supply. The data are based on resources which may no longer be totally accurate. However, this report is retained as a service in lieu of current data.
PENGGUNAAN LEMBAR KERJA SISWA BERBASIS MODEL PEMBELAJARAN GUIDED DISCOVERY LEARNING TERHADAP KEMAMPUAN BERPIKIR KRITIS
Authors: Jona Pebri Hendrik , Permatasari Rindah , Eveline Erlin
Published: March 2024

This research was conducted at Belimbing 1 State High School. This research aims to determine the effect of student worksheets based on the guided discovery learning model on critical thinking.This type of research is quantitative, using a quasi-experimental method with a nonequivalent control group design. The sample in this study consisted of 47 students, of which the control class consisted of 24 and the experimental class consisted of 23. Data collection techniques use written tests with research instruments in the form of essay questions. Data were analyzed using the t-test. Theresults of data analysis using the t-test in the control class and experimental class showed that Tcount was greater than Ttable, namely 5.201 2.01410 and Sig. (2-Tailed) = 0.000 0.05. It is concluded that there is a significant influence on the use of student worksheets based on the Guided Discovery Learning learning model on critical thinking skills. It was concluded that there was an increase in critical thinking skills after learning using student worksheets based on the Guided Discovery Learning learning model in the high category. In this way, student worksheets based on the Guided Discovery Learning learning model are able to foster students' critical thinking abilities. Keywords       : Guided Discovery learning model, Critical Thinking Ability, Student Worksheets.
Menyelami Makna dan Filosofis Budaya Tumpeng sebagai Simbol Identitas Kearifan Lokal Bagi Masyarakat
Authors: Pranoto Damianus Suryo
Published: March 2024

The focus of this research is on the meaning of cultural and philosophical purity of tumpeng for the people of Kalisongo as an identity of local wisdom in cultural diversity. For the people of Kalisongo, tumpeng culture is a formal rite of thanksgiving that is held once a year. So, the author in this study wants to elaborate the meaning and philosophy of tumpeng in Kalisongo society. This reveals that tumpeng culture is a great thanksgiving because all families are also present to thank God for all the fortune and results received in their lives every day. Tumpeng culture for the Kalisongo people has become a local tradition that is carried out formally. That tumpeng culture is a means to give thanks to others and God who has shared abundant fortune and results. So in this culture contains several values, namely the value of human dignity, respect, kinship, solidarity, and social values. The purpose of this study also elaborates on understanding how the Kalisongo people interpret the cultural and philosophical purity of tumpeng as a distinctiveness for them to build relationships with others and God.
Perancangan Sistem Informasi Penjualan Barang Berbasis Website di Mulya Jaya Putra Meubel Rancaekek
Authors: Trayana Anjas , Rohmanto RickyÂ 
Published: March 2024

This research focuses on the design of a web-based information system for selling furniture at Mulya Jaya Putra Meubel, located in Rancaekek, Bandung. The study aims to address the shortcomings in the current sales and promotion strategies. The proposed system encompasses online sales services and product information, aiming to enhance service availability beyond working hours, expand market reach, and provide detailed product information. The study benefits Mulya Jaya Putra Meubel by improving service quality, aids AMIK Al Maâ€™soem students as a reference, serves as an academic benchmark for the author, and enriches the reader's knowledge.
Communication Patterns between Generations via Family WhatsApp Groups (Case Study: Amarta Family)
Authors: Halim Dary
Published: March 2024

This research is inspired by the rapid development of the digital era which has shifted the place of communication from the real world to social media platforms, in this case the WhatsApp application, so that it has different patterns in each generation. Therefore, in analyzing the generations of WhatsApp group members, researchers tried to divide and classify family members into generation Y and generation Z according to their birth line. The aim of this research is to determine family communication patterns for each generation on the WhatsApp application. This research uses a descriptive qualitative approach. The subjects of this research are members of the Amarta family who are members of the family WhatsApp group. The sampling technique was purposive sampling and direct interviews. The research results show that there is a unique communication pattern in the WhatsApp Family group, each generation has the same communication pattern, namely the star pattern where each generation communicates, and each group member is free to talk and provide feedback. without any restrictions. or persuasive actions from generation Y and generation Z.
IMC Strategy and Strengthening of Restaurant Brand based on Sultanate Cultural Heritage in The Recovery Period Covid-19
Authors: Rahmawati Shita , Gusfa Henni , Makkuraga Afdal
Published: March 2024

The development of the hospitality business, especially special restaurants that serve the Sultan's favorite dishes, requires an appropriate marketing communication strategy. Tourism and hospitality business recovered the fastest during the recovery from the Covid-19 pandemic. This research aims to create the right integrated marketing communication (IMC) strategy to reach the targeted market. Using qualitative research methods, inductive and constructivist paradigms, as well as data collection through the field and virtual world observations, in-depth interviews, and literature studies and then triangulated to produce valid research results. Currently, IMC is experiencing rapid development, not only in terms of content but also in terms of media and selection of messengers. If IMC 1.0 focuses on product content, then in IMC 4.0 the customer must be the main focus, so the communication content material created must be based on the principle of benefits and added value received by customers. such as getting new experiences, enjoying a unique and authentic taste, self-existence and others. Bale Raos restaurant has been able to create the right IMC but of course it needs improvement for more optimal results. The most important suggestion, Bale Raos Resto must review and reorganize its IMC program and improve marketing media in terms of content, format and appearance so that it is more appealing to the customer's sensory senses. meet the principle of customer benefits.
A Proposed Categorization of Meta-Analysis, Their Respective Example Conceptual Frameworks, and Applicable R Packages for Education Research: A Review
Authors: Savatsomboon Gamon , Yurayat Phamornpun , Chanprasitchai Ong-art , Narkbunnum Warawut , Sharma Jibon Kumar , Svetsomboon Surapol
Published: March 2024

The paper has three major objectives. The first objective of the paper is to synthesize and define common categories of meta-analysis. The second objective is to propose a way to comprehend these common categories of meta-analysis through learning from their respective generic conceptual frameworks. The third objective is to point out which R packages to use to conduct a meta-analysis for each category presented in this paper. In practice, research novices may not know where to begin to learn a topic of meta-analysis for their research. Furthermore, they may not know how the topic of meta-analysis progresses from basics to advanced. This makes it almost next to impossible to use meta-analysis in their research. Certainly, this is problematic. Thus, this paper intends to help research novices overcome this problem. To achieve this, the three objectives mentioned at the beginning were implemented. To propose a synthesis of common categories of meta-analysis along with their respective definitions, a literature review was used as a method to synthesize and define the common categories of meta-analysis presented in this paper. Here, synthesizing meta-analysis categories in one figure would make it much easier for research novices to see the breadth of the subject in question. To propose an easy way to understand the concepts of meta-analysis through learning from their respective generic conceptual frameworks, personal experience was used as a method to make that offering. Here, it is encouraged that research novices should go beyond the definitions of categories of meta-analysis. They can try to frame their research by using example conceptual frameworks presented in the paper as a starting point. To point out which R packages to

use with what categories of meta-analysis, a literature review was used as a method to identify those appropriate R packages available. Here, it would be useful for research novices to know which R packages they may need for their meta-analysis research. In summary, the contributions of the paper here would make research novices see and understand the common categories of meta-analysis from the bottom to the top of the pyramid, also offers an easy way to understand the common categories of meta-analysis by illustrating how to develop conceptual frameworks for the common categories of meta-analysis, and finally recommending the R packages to be used with the categories of meta-analysis. Ultimately, we hope that research novices will be able to use meta-analysis successfully in their research.
Efeitos de um programa de treinamento combinado sobre os parâmetros antropométricos e composição corporal em voluntários com Diabetes Mellitus tipos 2
Authors: Figueiredo Paloma de Oliveira , Rodrigues Sabrina Caixeta , Domingos Mateus Eduardo de Almeida , Silva Natália Maciel , Silva Elisangela , Silva Júnior Autran José da
Published: March 2024

Introdução: A obesidade é uma pandemia e relaciona-se a comorbidades, mortalidade e seus elevados custos financeiros no mundo e no Brasil. Sobrepeso e obesidade representam o 6º fator de risco de mortes no mundo e apresentam fatores relacionados a diabetes mellitus tipo 2 (DM2). Dentre os fatores, acúmulo de lipídios ectópicos, disfunção mitocondrial, estresse do retículo endoplasmático e inflamação do tecido adiposo que estão relacionados a gênese da resistência à insulina e DM2. A participação em um programa de treinamento físico regular é uma das terapias não medicamentosas importantes para a redução e manutenção do peso corporal e dos fatores relacionados a DM2. Objetivo: analisar o comportamento de parâmetros antropométricos e da composição corporal em voluntários diabéticos tipo II submetidos a um programa de treinamento combinado. Material e métodos: a amostra constou de 30 voluntários, 62,7± 6,5 anos, 1,6± 0,1m residentes em Muzambinho/MG, participaram de programa de treinamento combinado de 3 sessões semanais, 60 minutos de duração, intensidade moderada. Estudo foi aprovado pelo CEP (parecer no 6.127.650, 19/06/2023). Resultados: não foram observadas diferenças significativas nos parâmetros antropométricos estudados, exceto relação cintura quadril. Conclusão: o programa de treinamento combinado foi capaz de reduzir alguns parâmetros antropométricos e da composição corporal, porém sem significância. Sugere-se que outros estudos possam incluir a presença de profissional da nutrição para melhor orientação alimentar e controle do balanço energético. Como também, sugere-se que, para parâmetros antropométricos e composição corporal para voluntários com DM2 nesta faixa etária, haja necessidade de um programa crônico de treinamento, que possa ter maior duração e controle sobre a ingestão alimentar.
Does Does Inflation and The Number of Taxpayers Affect Income Tax?
Authors: Fachrunnisa Zidni Husnia , Luthfi Rifna Ninda
Published: March 2024

Income tax is the largest state revenue, and the COVID-19 pandemic impacted decreasing income tax in 2020. This study examines factors from outside the policy of the Directorate General of Taxes, such as inflation and factors from inside the Directorate General of Taxes, namely the number of taxpayers affecting income tax. This study uses secondary data from monthly realization data and income tax art. 25 targets during 2017-2020 at the Yogyakarta Tax Office (KPP Pratama Yogyakarta). The sample retrieval technique in this study uses a saturated sample method. Sample this study of 48 data. The data analysis technique used is multiple linear regression analysis. The results show that inflation does not affect income tax, while the number of taxpayers has a negative effect on income tax. From the results of this study, the greater the number of registered taxpayers, the lower the income tax revenue. Indonesia uses an internal self-assessment system to calculate taxes, and the taxes paid depend on a financial report sent to the tax office. So, corporate taxpayer compliance greatly determines the amount of income tax. This result implies that the government can optimise corporate taxpayer compliance through the Ministry of Finance or the general directorate of taxes. This study only uses income tax art. 25 deposited by corporate taxpayers.
Gender Gap: Family Support, Perceived Work Productivity and Job Satisfaction on Working from Home
Authors: Rahmi Devi Yulia , Mardiah Fatma Poni , Sufiawan Nur Ari
Published: March 2024

The purpose of this study is to test whether family support has a positive effect on job satisfaction. In addition, to find out whether there was a gender gap in perceived work productivity and job satisfaction between men and women both before and during the Covid-19 pandemic and whether perceived work productivity and job satisfaction did not experience any difference both before the COVID-19 pandemic and after the occurrence of the COVID-19 pandemic. A quantitative approach was used to distribute questionnaires using a purposive sampling technique to 62 employees working from home in West Sumatera in 2021. Simple regression MANOVA was conducted to analyze the data. The result of the study found that family support and job satisfaction have a positive and significant effect. Another finding is that there was no gender gap in perceived work productivity and job satisfaction between men and women before and during the Covid-19 pandemic. In addition, there was no difference between job satisfaction and perceived work productivity, both before the Covid-19 pandemic and during the Covid-19 pandemic. The research implied that it assists companies and managers in making decisions and considering the sustainability of working-from-home programs for their employees and workers. In addition, companies and agencies are also asked to create an effective working-from-home model for women and men. Furthermore, it gives trust to families to continue supporting each other to create a healthy psychological environment when facing the COVID-19 pandemic. This study tries to see whether there are gender differences between men and women in terms of perceived work productivity and job satisfaction when working from home. The results of the different tests show this is different. This is also the case with the difference between conditions before and during Covid-19. It shows that there is no difference in perceived work productivity and job satisfaction between men and women.
Understanding of Requirements Engineering using The Three Dimensions of Requirements Engineering Method in Platform Development
Authors: Sari Risna , Anggi Muhammad Rifa'i  , Muhammad Salimy Ahsan  , M Ilham Arief  , Mohammad Rezza Pahlevi
Published: March 2024

Requirements engineering is a critical activity in a development system project, the increasing need for complexity of software development and the heterogeneity of stakeholders in motivating the development of methods and the need to evaluate the engineering requirements needed and aim to lead to a large scale. This study presents a paper in an empirical form that aims to identify and understand the characteristics of the advantages and limitations of the developed platform so that we can know the challenges that will be faced, such as expectations and input from experts for the development of the platform that we develop so that it can be in accordance with what users expect. We conducted this research with the aim of understanding the engineering requirements in the research we developed by utilizing the three dimensions of the requirements engineering method, which consists of requirement elicitation, requirement specification, and requirement validation and verification. The research we conducted managed to understand the stages of needs engineering by producing many documents that help the platform development process. We get the most important UI value from attractiveness, clarity, efficiency, accuracy, stimulation, and novelty, which is 63.2% with a very interest rating, 55.6 with a very interest rating, 57.9% with a very interest rating, 44.4% with a balanced rating between interesting and very interest, 52.6% with an interesting rating, 42.1% with a very interesting rating. We get product values consisting of attractiveness, clarity, efficiency, accuracy, stimulation, and novelty, namely 68.4% with a very interest rating, 52.6% with an interest ng rating, 52.6% with a very interest rating, 47.4% with a balanced rating between interesting and very interest, 47.4% with a balanced rating between interesting and very interest, 47.4% with a balanced rating between interesting and very interest
The Implementation Green Building at Syamsudin Noor Airport
Authors: Ahmad Busairi  , Tambun Madschen SMOSS , Agustina Hotma Uli Tumanggor
Published: March 2024

The development of Syamsudin Noor Airport is expected to have a major impact on the economy of the people of South Kalimantan. However, the construction of airports will have an impact on the environment due to the increasing number of human activities. And to anticipate these adverse effects, Syamsudin Noor Airport applies the concept of Green Building. The purpose of this study is to provide a descriptive picture of the extent to which Syamsudin Noor Airport has implemented the concept of green building. From the observations, Syamsudin Noor Airport has implemented green buildings such as solar panels, the use of bright glass that allows natural light to enter the terminal space, wastewater treatment facilities, green open spaces in the airport terminal area, bicycle parking and shower compartments, room temperature settings that create comfort in working, and the presence of no-smoking signs. With the implementation of green buildings at Syamsudin Noor Airport to meet the service standards set in the Presidential Law of the Republic of Indonesia No. 1 of 2009, supporting an environmentally friendly workplace and reducing operational costs.
Workshop Pengolahan Data Nilai Siswa Menggunakan Microsoft Excel di SD Negeri Jumeneng
Authors: Anita Fira Waluyo  , Irma Handayani  , Ikrima Alfi  , Wahyu Sri Utami  , Farida Ardiani  , Selfi Artika
Published: March 2024

Workshop on processing student grades data using Microsoft Excel is a training activity that aims to introduce the use of Microsoft Excel in managing and analyzing student grades data effectively. This workshop is aimed at teachers at SD Negeri Jumeneng with the aim of increasing their understanding of using Excel as a tool for processing data. In this workshop, the participants will be given an explanation regarding the use of Excel in processing student grade data. The material includes an introduction to relevant basic Excel formulas such as SUM, AVERAGE, MAX, MIN, IF, and others. In addition, participants will also be given guidance on graphing student grade data using Excel. This workshop was carried out through a practical approach by providing training to participants to apply Excel formulas and functions in processing student value data. It is hoped that this workshop will provide significant benefits for teachers at SD Negeri Jumeneng in managing and analyzing student grade data more efficiently using Microsoft Excel.
Hemicoreia na infância
Authors: Andrade de Oliveira Bruna , R. Vasconcellos Luiz Felipe
Published: March 2024

O diagnóstico etiológico de quadros coréicos é amploe algumas características da apresentação auxiliam noraciocínio diagnóstico, como o tempo de instalação do quadro(agudo/crônico), a distribuição corporal (focal/generalizada) esintomas associados. Na infância, a principal causa da formaaguda é a coreia de Sydenham. Descrevemos o caso de umapaciente do sexo feminino de 13 anos que apresentouhemicoreia de instalação aguda relacionada a febre reumática,sendo a manifestação dimidiada atípica nesta condição.
Unveiling the Dual Talents
Authors: Da Mota Gomes Marleide
Published: March 2024

This narrative review approaches four exceptional

neuroscientists whose lives embody the convergence of scientific innovation and artistic expression. Jean-Martin Charcot (1825-1893), William Richard Gowers (1845-1915), Harvey Williams Cushing (1869-1939), and Santiago Ramón y Cajal (1852-1934) remain icons in the neurosciences. Not only did these four luminaries make groundbreaking advances in neuroscience, but they also possessed artistic abilities, especially Cajal. Their lives exemplify the harmony between scientific rigor and creative expression. Through their interdisciplinary talents, they illustrated how art and science are inextricably linked, enhancing their scientific endeavors through artistic skills. This article provides insight into the intriguing relationship between the arts and neuroscience, showing how these notable figures leveraged their artistic aptitude to advance scientific communication and understanding.
Journey through Artistic Eras depicting Dreams, Sleep, and its Disorders
Authors: Da Mota Gomes Marleide
Published: March 2024

This narrative review presents a comprehensive

examination of artistic periods since the Renaissance, paralleling the evolution of neurology and pictorial artistic expression about sleep, ending with the importance of the contemporary digital era. Over the centuries, artists have been drawn to the enigmatic themes of dreams, sleep, and their disorders, using them to explore the complexities of the human condition, emotions, and the interaction between reality and imagination. Thus, drawing references from diverse artistic eras, including their pictorial representations of sleep, alongside milestones in the history of neurology, this study reveals a rich interconnectivity between art, neurological advances, and social change.
Business Sustainability on Coffee Shop Business District (Study on Sudimoro Coffee Business District Malang, Indonesia)
Authors: Purwadi Muhammad Guntur , Djatmika Ery Tri , Handayati Puji
Published: March 2024

This is a qualitative study investigates the business sustainability in Sudimoro Coffee Business District at Malang City from EGSEE aspect and principles of business sustainability. Interviews with senior staff, managers, customers, local government representatives, and business professionals are used to collect data. Customers, managers, and owners of coffee shops are examples of key informants. Comprehensive interviews with top staff members and clients validate assertions made by company proprietors. Local government representatives and a business professional with a comparable background in the field are examples of comparative data.
Gaya Kepimpinan Demokratik Pentadbir Sekolah dan Hubungannya dengan Kerja Berintegriti dalam kalangan Guru
Authors: Lang Angela , Mohd Noor Mohamed Yusof
Published: March 2024

Kajian-kajian lepas menunjukkan hubungan positif antara persepsi terhadap kepimpinan demokratik dan disiplin kerja. Ini memberikan gambaran bahawa hubungan yang erat di antara pemimpin dan subordinat dapat mencetuskan semangat kerja yang tinggi. Namun, apakah kesan kepimpinan demokratik terhadap integriti guru di Zon Kapit? Kajian ini mengeksplorasi hubungan antara kepemimpinan demokratik pengetua dan integriti guru di Sekolah Menengah Zon Kapit, Malaysia. Dengan menggunakan pendekatan kuantitatif dan borang soal selidik, kajian ini memeriksa persepsi guru terhadap tingkat kepemimpinan demokratik pengetua dan tahap integriti mereka. Dapatan menunjukkan bahawa guru menyatakan tahap yang tinggi dalam kepemimpinan demokratik pengetua dan integriti guru secara keseluruhan. Analisis menunjukkan perbezaan dalam persepsi guru terhadap beberapa aspek kepemimpinan demokratik, terutama dalam keputusan yang melibatkan perkembangan sekolah. Hasil kajian juga menggambarkan bahawa walaupun integriti guru dianggap tinggi secara umum, terdapat perbezaan pandangan dalam aspek konsistensi dalam amalan baik. Selain itu, kajian ini membahas implikasi teori terhadap keberhasilan sekolah dan kualiti pengajaran. Kepentingan pendekatan kepemimpinan demokratik dan integriti guru sebagai faktor penentu dalam membentuk sekolah yang berjaya dan pembelajaran yang bermutu ditekankan. Implikasi praktikal termasuk peningkatan latihan kepemimpinan demokratik dan penekanan pada partisipasi guru dalam pengambilan keputusan. Walaupun kajian ini memberikan wawasan yang bernilai, terdapat batasan metodologi dan geografi yang perlu diperhatikan. Kajian masa depan disarankan untuk fokus pada hubungan antara kepemimpinan demokratik dan motivasi guru, perbandingan gaya kepemimpinan dalam konteks bandar dan luar bandar, serta pengaruh budaya tempatan terhadap amalan kepemimpinan demokratik. Dengan demikian, kajian ini menyumbang kepada pemahaman yang lebih baik tentang dinamika sekolah menengah dan keberhasilan pendidikan di Malaysia.
SAĞLIK ÇALIŞANLARINDA MOBBİNG: ÖLÇEK GELİŞTİRME VE GÜVENİRLİK ÇALIŞMASI
Authors: Yardımcı Hasret
Published: March 2024

İş yerinde mobbing kavramı, bir veya birkaç kişinin bir başkasına sistematik bir şekilde düşmanca davranışlarda bulunması olarak tanımlanmaktadır. Mobbinge maruz kalan kişi psikolojik, fiziksel ve ruhsal olarak çöküntüye uğramaktadır. Bu araştırmada amaç, sağlık çalışanlarına yönelik mobbing ölçeği geliştirmek ve geçerlik, güvenirlik analizlerini yapmaktır. Çalışmada nicel araştırma yöntemi kullanılmış, betimsel tarama modelinden yararlanılmıştır. Çalışmanın örneklem grubunu KKTC devlet hastanelerinde çalışan 318 sağlık çalışanı oluşturmuştur. Açımlayıcı Faktör Analizi (AFA) sonuçlarına göre faktör yükü 0.40’dan düşük olan maddeler ölçekten çıkarılmış; ölçek, 20 madde ve üç alt faktörden oluşmuştur. Ölçeğin toplamda açıkladığı varyans % 50,055 ve cronbach alfa iç tutarlılık katsayısı ise 0.895 olarak hesaplanmıştır. Analiz sonuçlarına göre sağlık çalışanlarına yönelik mobbing ölçeğinin geçerli ve güvenilir bir ölçek olduğu ifade edilebilir.