bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of E-Commerce Use Level, Social Capital, Usage Attitude on Digital Utilization Performance
Authors:   Korea Association for International Commerce and Information, Kwon Hyuk
Published: April 2023

It is true that the digital world is affecting our society with various positive and negative factors, and the resulting digital inequality can lead to various social problems. In this regard, this study obtained survey data from 7,000 general citizens and conducted research using SPSS in order to identify the impact of digital capabilities on digital utilization performance and to devise measures to strengthen the digital capabilities of the people. As a result of the analysis, first, it was analyzed that e-commerce use level and digital use attitude had a significant effect on digital economic activity, while digital social capital had no significant effect on digital economic activity. Second, it was analyzed that e-commerce use level, digital social capital, and digital use attitude had a significant effect on life satisfaction. Third, it was analyzed that e-commerce use level, digital social capital, and digital use attitude had a significant effect on digital use performance. This study is differentiated in that it increased the reliability of the study by setting gender, age, and household income as control variables. Therefore, additional research should be conducted considering various demographic variables (household, education level, etc.) based on the data obtained during the period when face-to-face is active
Application of the pulmonary embolism rule-out criteria (PERC rule) and age-adjusted D-Dimer in patients undergoing computed tomography pulmonary angiography for diagnosis of pulmonary embolism
Authors: Sprockel Diaz John Jaime , Veronesi Zuluaga Luz Amaya , Coral Coral Diana Carolina , Fierro Rodriguez Diana Marcela
Published: April 2023

Abstract Background Diagnosis of pulmonary embolism (PE) constitutes a challenge for practitioners. Current practice involves use of pre-test probability prediction rules. Several strategies to optimize this process have been explored. Objectives To explore whether application of the pulmonary embolism rule-out criteria (PERC rule) and age-adjusted D-dimer (DD) would have reduced the number of computed tomography pulmonary angiography (CTPA) examinations performed in patients with suspected PE. Methods A retrospective cross-sectional study of adult patients taken for CTPA under suspicion of PE in 2018 and 2020. The PERC rule and age-adjusted DD were applied. The number of cases without indications for imaging studies was estimated and the operational characteristics for diagnosis of PE were calculated. Results 302 patients were included. PE was diagnosed in 29.8%. Only 27.2% of ‘not probable’ cases according to the Wells criteria had D-dimer assays. Age adjustment would have reduced tomography use by 11.1%, with an AUC of 0.5. The PERC rule would have reduced use by 7%, with an AUC of 0.72. Conclusions Application of age-adjusted D-dimer and the PERC rule to patients taken for CTPA because of suspected PE seems to reduce the number of indications for the procedure.
Retrospective evaluation of canine anal sac carcinoma (260 cases) in Brazil: late detection and failures in lymph node evaluation
Authors: Paiva Felipe N. , Moreira Stella H. , Linhares Laís C.M. , Sueiro Felipe A.R. , Nardi Andrigo B. , Jark Paulo C.
Published: April 2023

ABSTRACT: Anal sac neoplasms are common in companion animals, and the epidemiological profile has been extensively described in international studies; however, national data are still lacking. Data on the Brazilian reality of anal sac carcinoma cases’ diagnosis and treatment are also scarce. The purpose of this study was to retrospectively evaluate cases of canine anal sac carcinoma and assess the profile of involvement, tumor size, and lymphatic invasion at the time of diagnosis. Information was obtained from Vetpat laboratory database, from 260 cases spanning a 12-year period (2010-2021). In histopathological evaluation at the time of diagnosis, data on sex, age, and race were described, as well as tumor size and lymphatic invasion. The presence of metastasis was also assessed in cases where lymph nodes were sampled. Simple descriptive statistical analysis was used to evaluate the data. Adult and elderly, female, and mixed-breed animals were more involved, indicating differences from international studies that can be attributed to sociocultural factors. In terms of tumor size, it was observed that 93% of the cases had the largest diameter above 2.5cm. Only 7% of the cases had the largest diameter below 2.5cm, demonstrating the often late diagnosis and the importance of rectal palpation examination during the general physical assessment of canine patients, particularly at an advanced age. Regarding lymphatic invasion and affected lymph nodes, 50% of the cases had lymphatic invasion described in the histopathological examination. However, only 5% of the lymph nodes were sent along with the primary tumor, indicating the disease’s aggressive behavior but with possible metastases underdiagnosed.
Premature mortality due to noncommunicable diseases in Brazilian capitals: redistribution of garbage causes and evolution by social deprivation strata
Authors: Malta Deborah Carvalho , Teixeira Renato Azeredo , Cardoso Laís Santos de Magalhães , Souza Juliana Bottoni de , Bernal Regina Tomie Ivata , Pinheiro Pedro Cisalpino , Gomes Crizian Saar , Leyland Alastair , Dundas Ruth , Barreto Maurício Lima
Published: April 2023

ABSTRACT Objective: To analyze premature mortality due to noncommunicable chronic diseases (NCDs) in Brazilian capitals and the Federal District (DF) after redistribution of garbage causes and the temporal evolution according to social deprivation strata in the 2010 to 2012 and 2017 to 2019 triennia. Methods: Corrections were applied to the Mortality Information System (Sistema de Informação sobre Mortalidade – SIM) data such as the redistribution of garbage codes (GC). Premature mortality rates due to NCDs were calculated and standardized by age. The differences among NCDs mortality rates were analyzed according to the Brazilian Deprivation Index (Índice Brasileiro de Privação – IBP) categories and between the three-year periods. Results: In the capitals as a whole, rates increased between 8 and 12% after GC redistribution and the greatest increases occurred in areas of high deprivation: 11.9 and 11.4%, triennia 1 and 2, respectively. There was variability between the capitals. There was a reduction in rates in all strata of deprivation between the three-year periods, with the greatest decrease in the stratum of low deprivation (-18.2%) and the lowest in the stratum of high deprivation (-7.5%). Conclusion: The redistribution of GC represented an increase in mortality rates, being higher in the strata of greater social deprivation. As a rule, a positive gradient of mortality was observed with increasing social deprivation. The analysis of the temporal evolution showed a decrease in mortality from NCDs between the triennia, especially in areas of lower social deprivation.
Violence Against LGB+ people in Brazil: analysis of the 2019 National Survey of Health
Authors: Vasconcelos Nádia Machado de , Alves Francielle Thalita Almeida , Andrade Gisele Nepomuceno de , Pinto Isabella Vitral , Soares Filho Adauto Martins , Pereira Cimar Azeredo , Malta Deborah Carvalho
Published: April 2023

ABSTRACT Objective: To analyze the association between self-reported sexual orientation and violence in the Brazilian population. Methods: This cross-sectional epidemiological study used the 2019 National Survey of Health database. Total violence and its subtypes (psychological, physical, and sexual) were analyzed in the previous 12 months. Prevalence and odds ratio adjusted for age group were estimated, with their respective 95% confidence intervals, according to the self-reported sexual orientation of the Brazilian population aged 18 years and older. Statistical significance was set at 5%. Results: Most of the Brazilian population self-identified as heterosexual (94.75%) and 1.89% as LGB+. This percentage was lower than that of respondents who refused to answer the question (2.28%). The prevalence of violence in the general population of Brazil was 18.27%, and the most common subtype was psychological violence (17.36%). The LGB+ population was more than twice as likely to experience any type of violence. LGB+ women had the highest prevalence in all violence subtypes, and heterosexual men had the lowest. LGB+ women were over three times more likely to experience physical violence compared to heterosexual ones. Meanwhile, the probability of LGB+ men experiencing sexual violence was almost eight times higher than in heterosexual men. Conclusion: The prevalence of violence against the LGB+ population was high in the country. Public policies aimed at this population are necessary to fight discrimination against sexual diversity and ensure the rights of non-heterosexual people.
Commuting and work-related accidents among employed Brazilians, National Survey of Health 2013 and 2019
Authors: Malta Deborah Carvalho , Bernal Regina Tomie Ivata , Vasconcelos Nádia Machado de , Ribeiro Adalgisa Peixoto , Vasconcelos Lêda Lúcia Couto de , Machado Elaine Leandro
Published: April 2023

ABSTRACT Objective: To analyze the prevalence of work-related accidents, according to sociodemographic and occupational variables, in 2013 and 2019. Methods: Cross-sectional study using data from the National Survey of Health (PNS) 2013 and 2019. Typical work accidents (WA), commuting accidents (CA), and Total Work Accidents (TWA) were evaluated. Prevalence values and 95% confidence intervals (95%CI) of TWA in 2013 and 2019 were estimated according to the explanatory variables and for Federative Units and capitals. In 2019, the prevalence and 95%CI according to explanatory variables were estimated using prevalence ratios (PR), both crude and adjusted for sex and age group. Results: TWA prevalence decreased from 4.96% (95%CI 4.55–5.38) in 2013 to 4.13% (95%CI 3.80–4.46) in 2019. In 2013, the state of Pará prevailed in TWA, and the state of Mato Grosso in 2019. The prevalence of WA and CA in 2019 were: 2.64% (95%CI 2.37–2.91) and 1.60% (95%CI 1.40–1.80). In 2019, the prevalence for TWA were higher for men (PR: 1.92; 95%CI 1.62–2.27); in the 18-29 age group (PR: 2.71; 95%CI 1.99–3.68); people with elementary school and some high school (PR: 2.09; 95%CI 1.57–2.78); and Black individuals (PR: 1.43; 95%CI 1.12–1.84). People without formal employment contract had a lower prevalence of TWA (PR: 0.77; 95%CI 0.66–0.90). WA was higher in rural areas (PR: 1.32; 95%CI 1.09–1.60). Conclusion: There was a reduction in TWA between 2013 and 2019. Men, young people, Black people, and individuals with lower level of education, residents in rural areas had higher prevalence of WA in 2019, demonstrating a relationship between health-disease-accident processes.
Alcohol consumption among adolescents during the COVID-19 pandemic, ConVid Adolescents – Behavior Research
Authors: Malta Deborah Carvalho , Gomes Crizian Saar , Vasconcelos Nádia Machado de , Barros Marilisa Berti de Azevedo , Lima Margareth Guimarães , Souza Júnior Paulo Roberto Borges de , Szwarcwald Celia Landmann
Published: April 2023

ABSTRACT Objective: To describe the prevalence of alcohol consumption before and during the COVID-19 pandemic and to analyze the factors associated with this behavior during the period of social distancing among Brazilian adolescents. Methods: Cross-sectional study using data from the ConVid Adolescents survey, carried out via the Internet between June and September 2020. The prevalence of alcohol consumption before and during the pandemic, as well as association with sociodemographic variables, mental health, and lifestyle were estimated. A logistic regression model was used to assess associated factors. Results: 9,470 adolescents were evaluated. Alcohol consumption decreased from 17.70% (95%CI 16.64–18.85) before the pandemic to 12.80% (95%CI 11.85–13.76) during the pandemic. Alcohol consumption was associated with the age group of 16 and 17 years (OR=2.9; 95%CI 1.08–1.53), place of residence in the South (OR=1.82; 95%CI 1.46–2.27) and Southeast regions (OR=1.33; 95%CI 1.05–1.69), having three or more close friends (OR=1.78; 95%CI 1.25–2.53), reporting worsening sleep problems during the pandemic (OR=1.59; 95%CI 1.20–2.11), feeling sad sometimes (OR=1,83; 95%CI 1,40–2,38) and always (OR=2.27; 95%CI 1.70–3.05), feeling always irritated (OR=1,60; 95%CI 1,14–2,25), being a smoker (OR=13,74; 95%CI 8.63–21.87) and a passive smoker (OR=1.76; 95%CI 1.42–2.19). Strict adherence to social distancing was associated with lower alcohol consumption (OR=0.40; 95%CI 0.32–0.49). Conclusions: The COVID-19 pandemic led to a decrease in consumption of alcoholic beverages by Brazilian adolescents, which was influenced by sociodemographic and mental health factors, adherence to social restriction measures and lifestyle in this period. Managers, educators, family and the society must be involved in the articulation of Public Policies to prevent alcohol consumption.
Infraestrutura, expectativas e investimento: evidências empíricas para a América Latina
Authors: Fraga Jefferson Souza , Resende Marco Flávio da Cunha
Published: April 2023

Resumo Este artigo desenvolve, com base na perspectiva pós-keynesiana, a hipótese de que a deterioração da infraestrutura de um país inibe o investimento privado e reduz suas sensibilidades em relação aos seus determinantes, como a taxa de juros real, crédito, taxa de câmbio real, investimento público e infraestrutura. A hipótese é testada para o período 1985-2013 para seis economias da América Latina, empregando os estimadores dynamic fixed effects, pooled mean group e cross sectionally augmented pooled mean group em um painel dinâmico heterogêneo. Os resultados indicam o impacto positivo da infraestrutura sobre a formação de capital privado. Sugerem também que a deterioração do estoque de infraestrutura promove quedas na sensibilidade do investimento privado em relação aos seus determinantes, o que reduz a potência da política econômica em estimular o investimento privado via mudanças em seus determinantes.
Hearing screening using the uHear™ smartphone-based app: reproducibility of results from two response modes
Authors: Cunha Marta Luiza Santana da , Lopes Márcia da Silva , Meira Tatiane Costa , Corona Ana Paula
Published: April 2023

ABSTRACT Purpose Estimate the reproducibility of hearing screening results using the uHear™ smartphone-based app in two response modes: self-test response and test-operator. Methods Reliability study conducted with 65 individuals aged ≥18 years assisted at the Speech-language and Hearing Therapy clinic of a public higher-education institution. Hearing screening was conducted by a single researcher using the uHear app and earbud headphones in a soundproof booth. Participants responded to sound stimuli in both self-test response mode and test-operator mode. The order in which these two uHear test modes were applied was altered according to the entrance of each participant in the study. The correspondence between the hearing thresholds obtained from each response mode was analyzed and their Intraclass Correlation Coefficient (ICC) was estimated. Results A correspondence of ±5 dBHL >75% was observed between these hearing thresholds. The ICC values showed excellent agreement between the two response modes at all frequencies >40 dBHL tested. Conclusion The two hearing screening response modes using the uHear app presented high reproducibility, suggesting that the test-operator mode is a viable alternative when the self-test response mode is not recommended.
Triagem auditiva com o aplicativo para dispositivos móveis uHear™: reprodutibilidade dos resultados utilizando dois diferentes modos de resposta
Authors: Cunha Marta Luiza Santana da , Lopes Márcia da Silva , Meira Tatiane Costa , Corona Ana Paula
Published: April 2023

RESUMO Objetivo Estimar a reprodutibilidade dos resultados da triagem auditiva com o aplicativo uHear, utilizando dois diferentes modos de resposta, o modo autoaplicado e o modo com intermediação do pesquisador. Método Estudo de confiabilidade realizado com 65 indivíduos, maiores de 18 anos, que compareceram à clínica escola de Fonoaudiologia de uma instituição pública de ensino superior. A triagem auditiva foi realizada com o aplicativo uHear, em cabina acústica, utilizando fone intra-auricular e conduzida sempre pelo mesmo pesquisador. Os participantes responderam ao estímulo sonoro de maneira autoaplicada e com intermediação do pesquisador. A ordem de realização dos dois modos de resposta ao aplicativo uHear foi alternada de acordo com a entrada do participante no estudo. Foi analisada a correspondência entre os limiares auditivos obtidos com os dois modos de resposta, bem como estimado o Coeficiente de Correlação Intraclasse (ICC). Resultados Verificou-se uma correspondência de ± 5 dBNA superior a 75% entre os limiares auditivos obtidos nos dois modos de resposta. O ICC revelou concordância excelente entre os dois modos de resposta, em todas as frequências testadas, para intensidades superiores a 40 dBNA. Conclusão Os dois modos de resposta à triagem auditiva com o aplicativo uHear apresentam elevada reprodutibilidade, o que permite indicar o modo de resposta com intermediação do pesquisador como uma alternativa viável quando o modo autoaplicado não for recomendado.
Effect of duration and pressure of carbonation curing on the chloride profile in concrete
Authors: Dias Roberto Luiz , Beltrame Neusa Aparecida Munhak , Gonzalez Jordi Rius , Medeiros-Junior Ronaldo Alves
Published: April 2023

Abstract Carbonation curing alters the characteristics of the concrete's microstructure and can interfere with the penetration of aggressive ions. The objective of this article was to evaluate the influence of CO2 pressure and carbonation cure time on chloride profiles. Concrete specimens were cured by carbonation with CO2 pressures ranging from 5 to 25 Psi, for a time within the carbonation chamber of 8, 24, and 36 hours. These concretes were subjected to 30 wetting and drying cycles in NaCl solution to stimulate the chloride ingress. The carbonation depth and the microstructure of the concrete were monitored over time. Chloride profiles were obtained and modeled by 4 mathematical equations. The results showed that the combination of less time and CO2 pressure during carbonation curing potentiated the reduction of chloride penetration in concrete. Also, the carbonation curing conditions of 5 and 10 Psi for 8 hours reduced the chloride diffusion coefficient.
Analysis of Angiogenesis-Related Signatures in the Tumor Immune Microenvironment and Identification of Clinical Prognostic Regulators in Lung Adenocarcinoma
Authors: Zhou Qing , Chen Xi , Chen Qiuyan , Hao Lu
Published: April 2023

Tumor angiogenesis is considered to be an important part of the mechanism of tumor progression and metastasis, and its specific function in lung adenocarcinoma has not been fully studied. In this study, we used the transcriptome and genome data of lung adenocarcinoma patients to analyze the expression of 36 angiogenesis regulators in lung adenocarcinoma. Consensus clustering analysis divided lung adenocarcinoma samples into 4 subtypes, A, B, C, and D, and the expression of most angiogenesis regulators in subtype B was higher than that in other subtypes. Immunological analysis indicated that subtype B is likely to display the characteristics of a hot tumor with a more active TME. With the help of Lasso-Cox regression analysis, we successfully constructed a risk model involving five Angiogenesis Regulators genes (CCND2, JAG1, MSX1, STC1, TIMP1), which will be helpful for clinical personalized treatment and prognosis prediction. In addition, JAG1 has the highest mutation rate in tumors, and its cancer-promoting function is reflected in a variety of tumors, which provides important clues for the development of new broad-spectrum anti-cancer targets in the future. We successfully constructed a risk model involving five angiogenesis regulators genes (CCND2, JAG1, MSX1, STC1, TIMP1), which may be helpful for clinical personalized treatment and prognosis prediction. In addition, JAG1 has the highest mutation rate in tumors and plays a leading role in the protein interaction network. Its tumor-promoting function is reflected in a variety of tumors and may become a broad-spectrum anti-cancer target in the future.
Effects of Nonthermal Atmospheric Pressure Plasma Jet on Human Dental Pulp Stem Cells
Authors: Mousavi Seyedeh Fatemeh Peyro , Ganjovi Alireza , Eskandarizadeh Ali , Parirokh Masoud , Derakhshani Ali , Saidi Ali Reza , Falahat Amir
Published: April 2023

The effects of a nonthermal atmospheric plasma jet with argon and argon/oxygen (Ar/O2) gases on live human dental pulp stem cells (hDPSCs) were studied to verify tooth vitality in the pulp-capping process. Using MTT assay, the surviving hDPSCs after plasma jet exposure for 1, 2, and 3 min were counted. First, for the pulsed plasma jet the frequency varied from 10 to 50 kHz for 5 groups with Ar and 5 groups with Ar/O2 plasma jet. Later, with the alternating current (AC) plasma jet, the voltage was changed between 5.5 and 16.05 kV for 13 groups. The cells in the control group were only exposed to Ar and Ar/O2 gases. To control thermal damage to hDPSCs, optical emission spectroscopy was used. For data analysis, the ANOVA repeated measure was used. There were significant differences between the various frequencies and exposure durations (p < 0.05) for the Ar plasma. For the Ar/O2 gas, there were significant differences between frequencies (p < 0.001). For the AC plasma jet with Ar gas, there were significant differences between voltages (p < 0.001). At the higher pulsed jet frequencies, temperatures increased. Eventually, the suitable durations for root canal disinfection and hDPSC survival with the Ar pulsed jet were 2 and 3 min at 10 and 30 kHz, respectively. Since cold plasma disinfection keeps hDPSCs alive, it can be helpful in promoting tooth survival and durability for pulp capping in clinical treatments.
Soil–structure interaction behind integral bridge abutments
Authors: Wiechecki Michael , Thusyanthan Indrasenan , Nowak Paul , Sandberg Jessica
Published: April 2023

Integral bridges are preferred on infrastructure schemes as they have lower maintenance costs than a conventional jointed bridge. A key aspect of integral bridge design is the assessment of long-term passive resistance that develops in the abutment backfill due to seasonal movements of the superstructure. This resistance is currently defined by an intermediate earth pressure coefficient termed K*, and is typically evaluated using the limit equilibrium (LE) approach prescribed in BSI PD-6694-1:2011+A1:2020. This paper adopts the alternative numerical design approach and investigates the development of K* behind full-height abutments using soil–structure interaction (SSI) modelling in Plaxis-2D software. The study demonstrates that mobilised passive resistance is primarily a function of backfill and structural stiffnesses, and that the current LE approach does not capture the backfill resistance profile correctly. The effectiveness of the SSI method was verified by comparison to the LE method. The current study provides an SSI methodology that is an efficient design approach, and which is suitable for a wide variety of integral bridge arrangements beyond the current LE method applicability.
Patterns of progression of sound changes in a variety of Portuguese in contact with Italian immigration languages in Southern Brazil
Authors: Battisti Elisa , Santos Bruna Silva dos
Published: April 2023

The study deals with variable phonetic traits of Brazilian Portuguese (BP) in contact with Italian immigration languages. It focuses on the realization of an alveolar tap (weak-r) in onset position where one would expect an alveolar trill (strong-r) or its fricative variants (glottal/velar fricative): [ɾ]ápido instead of [r]ápido or [h]ápido ‘fast’, ca[ɾ]o instead of ca[r]o or ca[h]o ‘car’. The realization is relatively stigmatized and declining in younger generations (Azeredo, 2012; Frosi, Faggion & Dal Corno, 2017). The study uses methods from variationist sociolinguistics (Labov, 1972; Labov, 1994; Labov, 2001; Labov, 2010) to examine speech data of a southern Brazilian town, Flores da Cunha, founded by Italian immigrants in the late 19th century. The objective of the study is to identify the linguistic and social factors correlated to the realization of a weak-r and thus to elucidate the pattern of variation and change. Logistic regression performed with R (Venables, Smith & the R Core Team, 2022) in a real-time trend study with data from 1990 (VARSUL sample) and 2008–2009 (BDSer sample) shows that the process is relatively stable in the speech community and conforms to a pattern of generational change (Labov, 1994). Despite the tendency towards leveling of Flores da Cunha BP with supralocal patterns of Portuguese, the slow decline in the realization of weak-r suggests that the socioindexical value of the alveolar tap has changed in recent years, along with socioeconomic and cultural changes.
Walt Whitman: A Current Bibliography, Summer/Fall 2022
Authors: Folsom Ed
Published: April 2023

Walt Whitman: A Current Bibliography, Summer/Fall 2022.
Die Heilandskirche als Herrschaftsprogramm
Authors: Richter Hedwig
Published: April 2023

Die Heilandskirche am Port von Sacrow schwebt über dem Wasser, ihr Bild mit den filigranen Säulengängen spiegelt sich in der Havel. Die Schönheit des Ortes erzeugt über alle Fremdheit hinweg Resonanz. Dabei könnte uns der Bauherr der Kirche, Friedrich Wilhelm IV., kaum fremder sein. Unter den nicht wenigen verdrießlichen Gestalten der Hohenzollerndynastie war er eine besonders unerfreuliche. In einem Jahrhundert, in dem die Welt neu justiert wurde, suchte er das Heil in der Vergangenheit, und mit seinem Affront, die Kaiserkrone abzulehnen, trug er 1849 wesentlich zum Scheitern einer liberaleren Ordnung in Deutschland bei. Modern war sein reaktionärer Affekt auf die Moderne: sein Glaube an das Gottesgnadentum im bürgerlichen Jahrhundert des Konstitutionalismus, sein Zögern in der Ära der Beschleunigung und Revolution. Nur sein Kunstgeschmack entsprach der Zeit.
Concretes on a composite gypsum binder using limestone stone crushing waste
Authors: Natalia V Chernysheva , Othman Azmi SA , Motorykin Dmitry Aleksandrovich
Published: April 2023

The article discusses the possibility of obtaining Composite Gypsum Binders (CGB) and heavy concretes based on them using local raw materials from Palestine. As an active mineral additive in the composition of the composite gypsum binder, it is proposed to use finely dispersed quartz sand with a specific surface area of ​​500 m2/kg, on the surface of which, during grinding, a disturbed microlayer is formed containing a limited amount of amorphous SiO2, which is capable of binding Ca(OH)2 at ordinary temperatures with the formation of insoluble compounds, that is, it has pozzolanic activity, and as a result provides a significant increase in the strength of composites, increases their water resistance. Based on the developed composite gypsum binder with sufficiently high strength (24.8 MPa) and water resistance (K = 0.73), heavy concretes were obtained with a class of compressive strength B7.5 - B15, for use in residential, public, and industrial buildings in the form of load-bearing, self-supporting and enclosing structures.
A case of acute transverse myelitis following the AstraZeneca COVID-19 vaccine
Authors: Reema Madike , Andrew Lee
Published: April 2023

A 79-year-old man presented with gait dyspraxia approximately 2 days after receiving the first dose of the AstraZeneca COVID-19 vaccine (AZ-COVID-19-vax). He had no previous active issues and was currently on no medications.
Characterization of recessively inherited X-Linked ichthyosis in Bajaur Agency
Authors: Ubaid Ullah , Abdul Waheed Shah , Midrar Ullah , Inaam Ullah
Published: April 2023

Background: Recessively inherited X-linked Ichthyosis (XLI) is the second most generic form of Ichthyosis and is characterized by scaly, dry, thickened, and mild erupted skin. It is caused by a mutation in the STS gene ensuing lower production of Steroid sulfatase. A current study was performed to characterize XLI and its complications in patients of Bajaur Agency, Pakistan. We also wanted to record critical factors affecting the progression of XLI. Methods: An Ichthyosis examination questionnaire was prepared and detailed information about the symptoms and management was recorded from 51 affected male patients of 17 families. Personal data such as age and gender were also recorded. Results: Our results indicate that 53% of the patients were collodion while other symptoms appeared in the first month after birth. Almost every part of the patient has symptoms of the disease; scales were found on the extensor and flexor muscles (98%) of limbs followed by the ears (82.53%). All the patients had normal nails, palms and soles. Conclusion: The age of the patients seems to have a significant effect on the color of the scales changing from white to brown to blackish. The disease progresses with the age and worsens in cold, dry seasons. The pedigrees of all families show that disease passes from generation to generation according to the classical X-linked recessive inheritance. We recommend early diagnosis and treatment for effective management of the condition. Further work is required to elucidate the genetic, biochemical, and environmental factors involved in the disease.
Brain-computer interface applications to decrease phantom limb pain
Authors: Paula Ivone Rodríguez-Azar
Published: April 2023

Phantom limb pain is mainly experienced in people who have suffered limb amputation, its study and analysis are relevant to know the causes and help patients to reduce pain. On the other hand, brain-computer interfaces encode brain signals and decode them for communication with a device. Through the motor imagination of the movement of the amputated limb and with the help of a brain-computer interface, an amputee patient can reduce or eliminate pain. The objective of this paper is to give an introduction to brain-computer interfaces as a tool for the reduction of phantom limb pain. Therefore, the applications of interfaces in relation to pain are highlighted, some related studies are discussed, and their benefits and disadvantages are analyzed. Finally, it is established that phantom limb pain research benefits from incorporating brain-computer interfaces as part of non-pharmaceutical therapy because it is a tool that provides feedback on the reconfiguration of the cerebral cortex in relation to pain.
Visualisation and quantification of dendritic spines in cultured human Medium Spiny Neurons (MSNs) v2
Authors: Do Quyen
Published: April 2023

This protocol describes the visualisation of dendritic spines of human neurons cultured on coverslips in vitro and subsequent quantification using the software Imaris.
Spectrophotometric Quantification of Betacyanins in Plant Tissue Produced from the RUBY Reporter Gene v1
Authors: not provided matthew.morgan
Published: April 2023

RUBY is a visual reporter gene that produces beatnin, a betacyanin that appears red to violet in colour (He et al., 2020). To assay betanin (and other betalains) a spectrophotometric approach has been employed, as seen in Stintzing et al. (2003) and Grützner et al. (2021).
Custom open-chamber microfluidic fabrication v2
Authors: Do Quyen
Published: April 2023

This protocol described the fabrication of two- and three-open chambered microfluidics suitable for cell culturing using commercially acquired master mould.
The effect of Home Visit during the first six weeks of postpartum on the quality of life of primiparous women referred to Shiraz health centers of Shiraz University of Medical Sciences
Authors: Yazdani Khadije , Ghodsbin Fariba , Jahanbin Iran , Keshavarzi Sareh
Published: April 2023

Objective. To evaluate the effect of home visitation programs during the first six weeks of postpartum on the quality of life of primiparous women.

Methodology. Controlled clinical trial. The 52 primiparous women who were referred to healthcare centers of the University of Shiraz (Iran) were randomly assigned to either an intervention group (n = 26) or a control group (n = 26). An instrument was applied including demographic information and the Specific Postnatal Quality of Life (SPQOL) scale (30 items with Likert-type response options ranging from 0 to 4, the higher the score the better the quality of life). The intervention conducted during the first six weeks of postpartum consisted of an educational program developed during four sessions from 30 minutes to one hour, dealing with topics of nutrition, physical support, ways of having appropriate relations with the spouse, and exercises for the postpartum. During weeks 0 and 6, the SPQOF was applied in both study groups.

Results. Both groups were similar regarding the socio-demographic variables. The difference between SPQOL scores from the first and second evaluations was 39.6 in the intervention group versus 6.2 in the control group (p < 0.001).

Conclusion. The results from this study indicate that the home visitation program was related to improved quality of life of primiparous women during the first six weeks of postpartum.
FACTORS RELATED TO NURSING STAFF JOB SATISFACTION IN A MEDICAL AND SURGERY HOSPITAL
Authors: Molina Linde Juan Máximo , Avalos Martínez Francisco , Valderrama Orbegozo Laura Juliana , Uribe Rodríguez Ana Fernanda
Published: April 2023

Objective: to analyze the degree of job satisfaction of staff nurses working in a medical and surgical hospital, and to establish the socio-demographics and professional factors related to their job satisfaction.

Methodology: cross-sectional and performed on seventy five persons of the nursing staff of the medical and surgery hospital (total: 510) of Ciudad Sanitaria Virgen de las Nieves of Granada (Spain), by means of a self-administered and anonymous survey. The questionnaire has two parts: the first one is Font-Roja test (it measures the job satisfaction) and the second one are the socio-demographic and labor variables.

Results: the average age of the staff who answered the survey was 42.9 years; 72% women, married 64.9%; permanent staff; 58.7% hospitalization staff and a 67.6% have rotating turns. The Font-Roja degree of global satisfaction was medium (69.92 ± 10.48), range from 24 to 120. The best valued dimension is “interpersonal relation with the workmate” (3.82 ± 0.86) and the worse one is “professional promotion” (2.28 ± 0.75). The work place is a predicting element of the job satisfaction (ß=-0,297, p=0,018).

Analysis and discussion: a work place guaranteeing more job satisfaction for the nursing staff would improve the quality of care received by the patients of this type of personnel.
USE OF PAP IN WOMEN ATTENDING EARLY DETECTION OF CERVICAL CANCER: AN APPROACH TO MEETING THE SERVICE
Authors: Vega Chávez Jesús , Gutiérrez Enríquez Sandra Olimpia
Published: April 2023

Objective: to describe the satisfaction of service users with the timely detection of cervical cancer through the analysis of indicators and socio-demographic characteristics.

Methodology: descriptive study. 101 women participate; they have PAP test in July 2007 in 13 urban health centers from San Luis Potosi Health Department Jurisdiction 1. Socio-demographic characteristics and use of service indicators are measured, including also satisfaction level.

Results: the average age is 36 years old. Maximum level of education is ninth grade (42.6%) and 54.5% of the participants have Popular Insurance; 80.2% are married; the women that more attend for the first time are the youngest (18-31 years), and the married ones; and the ones that attend less are those between 51 and 61 years old. Those that are more willing for the first time are the married ones; and the ones with less attendance are the divorced, separated and widows. General knowledge about PAP test and uterine cervix cancer is adequate in 51.5% and 76.2%, respectively, whereas the accessibility is adequate in 67.3%. Satisfaction level was high on waiting time (66.3%); with complete, truthful, opportune, and understandable information (78.2%), as well as an appropriate treatment from health personal (87.1%) and accessibility (80.2%).

Conclusions: the users are satisfied with the service. In this article we find that Papanicolaou test is not associated with women satisfaction. Age and marital status are associated to the appointment for the PAP.
SERIOUS ILLNESS AS OPORTUNITY
Authors: Beltrán Salazar Óscar Alberto
Published: April 2023

Objective: to describe the meaning for gravely ill patients of the hospital experience in an Intensive Care Unit. Methodology: research study with phenomenological focus including nine mature people among 24 and 80 years of age who were critically ill and were hospitalized in an Intensive Care Unit. The in depth interview was the technique for gathering the information. The analysis of data was carried according to the outline proposed by Cohen, Kahan and Steeves. The study was carried in Medellín, Colombia from April to October, 2006. Results: a serious illness is an experience in which it is necessary “struggle” to leave the Intensive Care Unit, to return home and recover the freedom to decide. When leaving the patients learn, in the personal, professional and familiar spheres. Discussion: to suffer a serious illness means a situation of were people and their families learn and grow families. Conclusion: suffering a serious illness not only means to face the suffering, but also provides a reason to make decisions regarding the patients´ future life.
SELF-ASSESSMENT OF QUALITY OF LIFE AND AGING OF ALZHEIMER DEVELOPMENT RISK ADULTS
Authors: Zea Herrera María del Carmen , López Alzate María Elizabeth , Valencia Marín Claudia Marcela , Soto Gómez Juliana Andrea , Aguirre Acevedo Daniel Camilo , Lopera Restrepo Francisco , Oswald Wolf D. , Rupprecht Roland
Published: April 2023

Objective: describe the self assessment of the quality of life and the aging of a group of middle-age adult carriers and non-carriers of mutation E280A in gene Presenilin 1 for Early Onset Familial Alzheimer’s Disease and of elderly adults in Antioquia-Colombia. Study conducted from January 2005 to June 2007. Methodology: descriptive transversal study in which 162 asymptomatic people at risk of developing Alzheimer’s disease as a genetic consequence or as a consequence of the process of aging. They were subdivided into three groups: 27 carriers of the mutation, 39 non-carriers and 96 elderly adults. The study was conducted at the Neuroscience Group in Medellín (Antioquia) and at a gerontology center in Envigado (Antioquia) named Atardecer. Social-demographic characteristics were analyzed and quality of life and overall aging selfassessment tests were applied, which included the World Health Organization Quality of Life, and the Nürnberg -Self-Evaluation-List respectively. Statistic Analysis: The groups were described and they were compared to the variables of the study using Kruskall Wallis non-parametric anova and Mann-Whitney’s U-test. Results: the mean scores of the instruments to assess quality of life and overall aging of three groups of participants were above 50 points and below 55 points respectively. Conclusions: elderly adults assessed themselves as having a lower quality of life than carriers and non-carriers, especially in the physical health area, and in their perception of aging, in spite of carriers’ conditions, although in general the scores were good in all the groups.
THE CURRICULUM: PERSPECTIVES FOR ITS INTERPRETATION
Authors: Malagón Plata Luis Alberto
Published: April 2023

This article reflects on the concepts of curriculum, and considers its object of study, and the tendencies, currents or curricular perspectives that are more re-presentative. The idea of beginning the article with the search for a definition of curriculum and a delimitation of its object, points to clarify the discussion about the variables involved in the concept. The second section entails the discussion about currents or curricular perspectives, with the purpose of delimiting the reaches of each one in relation with the variable of pertinence. To portray, from the point of view of each one, which could favor the processes of social and integral pertinence. The expositions and experiences in respect to it, allows us to argument our cause.
PLANNING AND EDUCATIONAL GUIDE IN THE HIGHER EDUCATION EUROPEAN CONVERGENCE FRAMEWORK
Authors: Fernández Sola Cayetano
Published: April 2023

Present day societies are characterized by the globalization of their economies and, the fostering of a “knowledge-based society”. Higher education plays a part in these phenomena, and, in Europe, is undergoing an important reform seeking to homogenize the system of university degrees. These attempts come togetherin the European Space of Higher Education which will mean a new paradigm centred on “learning” and upheld by a system of common credits, teaching staffplanning, innovations in methodology, the professional competences and the handling of information in the constantly changing knowledge in today’s world.In this framework staff planning, and the production of Teaching Guides is of the utmost importance. The aim of which being an awareness on the part of the student of the benefits to be had when taking each course, what activities should be carried out, guidance on chronology, on assessment. Regarding the subject under discussion, we have evolved some reflections on the lines of each of these topics, putting forward a model illustrated with examples on how to make planning and teaching guides useful instruments for the student. We conclude stressing the importance of  a teaching plan for convergence and noting that despite the difficulties, changes are possible.
PROMOTION OF A POSITIVE LEARNING ENVIRONMENT
Authors: Barbosa de Sousa Leilane , Ferreira Moura Escolástica Rejane , Teixeira Barroso Maria Grasiela
Published: April 2023

Objective: to relate the promotion of a positive learning environment experience. Methodology: descriptive study with the theoretical and methodological approaches of the Reference Manual for Formation of Teachers Johns Hopkins Program for International Education in Reproductive Health, United States of America. An expositive class was developed by a master’s student (with the orientation of teachers of the “Methodology of Nursing” course) with the participation of 28 students and the incumbent teacher of the “Psychology applied to Health” course. The experience happened in November, 2006. Results: The participants expressed acceptance to the method and pointed out important aspects of a positive learning environment, such as dominance and confidence, dynamism in the oral presentation, opportunity forparticipation, practical application and summary of main points. Conclusion: the results focused the importance to review traditional educational paradigms considering the standpoint of the students, who are the protagonists of the process.
DEPRESSION IN A GROUP OF PENSIONERS BELONGING TO PHYSICAL ACTIVITY AND /OR ASSOCIATIONS PROGRAMS, UNIVERSIDAD DE ANTIOQUIA, MEDELLÍN 2005
Authors: Patiño V. Fredy Alonso , Cardona Arango Doris
Published: April 2023

Objective: To assess the frequency of depression in a group of pensioners belonging to physical activity and/or associations of Universidad de Antioquia. Materials and Methods: A cross descriptive study was carried between April and May 2005. One hundred pensioners taking part in physical activity and/or associations were selected: Fifty men and ﬁfty women. Median age: 65.7 years. The Yesavage Geriatric Depression Scale was applied and some demographic, economic, functional, affective, familiar and time use aspects were surveyed. Results: Six per cent total depression was found. Highest values were found in women, in people more recently retired, in people without labor activities after retirement, in people considering they suffer bad economic situation and in persons who do not performed physical activities. A statistically signiﬁcant was found especially between depression and the feeling of bad economic situation. Conclusions: Depression was inferior compared with other researches. That could be explained by the sample and possibly for the protective factor implicit in group sharing.
Discourse genres and most frequent mistakes in academic reports of nursing students
Authors: Arechabala María Cecilia , Avila Natalia , Catoni María Isabel , Riquelme Giselle , Aedo Carreño Vivian
Published: April 2023

Objective. To describe discourse genres most frequently used, and the most common mistakes in the construction of academic texts of nursing students of the Catholic University of Chile.

Me­thodology. Qualitative study carried out in 2006. 68 papers (27 individuals and 41 groups) were chosen. To identify the main gen­re in each text, the paper was characterized taking into account textual, discursive and pragmatic criteria. To identify the most fre­quent mistakes, they were reviewed according to the course they came from. Problems or mistakes categories were obtained by saturation.

Results. Discourse genres most frequently used by the students are case reports and bibliographic studies. Problems in the construction of the text were mainly linked to: inappropriate use of vocabulary, academic informality, and deficient construction of sentences.

Conclusion. The level of development of writing abilities is descriptive, existing deficiencies that deserve to be studied, aiming to develop strategies to decrease this problem.
Research output in nursing education in Colombia
Authors: Jiménez Gómez María Antonia
Published: April 2023

Objective. To build the state of the art in nursing education research in Colombia.

Methodology. Documentary research in which scientific output (surveys, articles, research reports) conducted between 1995 and 2005 was carefully and systematically reviewed. Information was obtained using instruments which allowed the characterization of nursing higher education institutions and its researchers, documentary sources related to the subject to contextualize in relation to the advances in nursing higher education, and finally libraries’ data bases from institutions with graduate degrees in education were consulted. Research outputs were analyzed individually and in groups after classifying them by analysis categories.

Results. Examination of the conceptualization, context of the research output and the study of the products allowed the identification of a higher research output in public universities of the central andean region where there are institutions with more than 50 years of experience, undergraduate and graduate programs including doctorates, teachers who have as one of their tasks researching, and also continuous learning is encouraged. The largest number of projects is in the pedagogy category, assessment and students. A high research thematic dispersion is shown and the level of identification, describing and determining prevail in the projects.

Conclusion. Research output in nursing education in Colombia is at a descriptive level, there is a great dispersion of research topics being the educational process the most developed one.