bluuebunny/crossref_metadata_2025 huggingface dataset:
Perancangan Sistem Pendukung Keputusan Menggunakan Metode Multi-Attribute Utility Theory (MAUT) Dalam Seleksi Pengangkatan Karyawan Tetap pada Dinas Pekerjaan Umum Kota Sawahlunto
Authors: Putra Dede Wira Trise , Oktavia Intan Sri , Swara Ganda Yoga , Yulianti Eva
Published: August 2022

Abstrak: Peningkatkan kinerja karyawan dilakukan dengan melakukan seleksi karyawan tetap dalam periode tertentu dan dilakukan secara internal. Permasalahan yang ditemukan dalam proses penilaian kinerja pegawai adalah pengangkatan karyawan harian menjadi karyawan tetap dengan prosedur penilaian langsung yang dilakukan oleh pimpinan. Salah satu masalah dengan metode yang digunakan adalah hasil penilaian beberapa karyawan yang tidak jauh berbeda dari beberapa kriteria penilaian. Sistem Pendukung Keputusan pengangkatan karyawan harian menjadi karyawan tetap merupakan suatu sistem yang mampu memberikan evaluasi kinerja pegawai yang akan dipromosikan. Proses pengambilan keputusan yang lebih cepat dalam sistem pendukung keputusan dapat digunakan untuk perencanaan terpadu untuk mengecilkan tingkat resiko kesalahan dalam pengambilan keputusan. Metode yang digunakan adalah Multi-Attribute Utility Theory yang memecah suatu masalah ke dalam beberapa sub sistem dengan kriteria acuan perhitungan adalah usia, lama bekerja, pendidikan, absensi, sertifikat pelatihan, pengetahuan pekerjaan, dan kerjasama. Sistem Pendukung Keputusan yang dirancang dapat digunakan sebagai rekomendasi bagi pengambil keputusan untuk menentukankaryawan harian yang layak diangkat menjadi karyawan tetap dengan hasil perhitungan menggunakan nilai tertinggi.Kata kunci: Sistem Pendukung Keputusan, Multi-Attribute Utility Theory, KaryawanAbstract: Employee performance improvement is carried out by selecting permanent employees for a certain period and is carried out internally. The problem in the employee performance appraisal process is the appointment of daily employees to become permanent employees with a direct assessment procedure carried out by the leadership. One of the problems with the method used is that the assessment results of some employees are not much different from some of the assessment criteria. The Decision Support System for the appointment of daily employees to become permanent employees is a system that can provide an evaluation of the performance of employees who will be promoted. A faster decision-making process in a decision support system can be used for integrated planning to reduce the risk of errors in decision-making. The method used is the Multi-Attribute Utility Theory which breaks down a problem into several sub-systems the calculation reference criteria are age, length of work, education, attendance, training certificates, job knowledge, and cooperation. The designed Decision Support System can be used as a recommendation for decision makers to determine daily employees eligible to be appointed as permanent employees with the calculation results using the highest value.Keywords: Decision Support System, Multi-Attribute Utility Theory, Employees
ENCOURAGING STUDENTS TO IMPROVE SPEAKING SKILLS THROUGH COMMUNITY LANGUAGE LEARNING
Authors: Kurnia Kurnia
Published: August 2022

Particularly for speaking skill, the students often find some problems. The problem frequently found is that their native language causes they difficult to use the foreign language. Other reason is because lack of motivation to practice the foreign language in daily conversation. English teacher should be able to motivate the learners in learning this foreign language. Motivation is a change of energy in a person's which is characterized by the emergence of affective and reaction to achieve the goals. It should be done by every English teacher in order that the students are interested to learn this language. English teacher must be able to manage the teaching by using certain method in the teaching-learning process, so that the students will like it without boring and despair. This research focused to find out whether community language learning method able to overcome the problem. It is proved by the difference between pre-test and post-test result of the three components speaking ability and final score of the students speaking ability
THE HUMOR STORY IN TEACHING READING COMPREHENSION
Authors: Tang Syamsu , Asrifan Andi , Chen Yan , Haedar Haedar , Agussalim Mutmainnah
Published: August 2022

The objective of the research were to find out whether or not the use of Humor Story can improve the students’ reading comprehension and Students interest at the Eighth of SMP Negeri 4 Pancarijang. This research employed a mixed method that applied monolingual class. The population of this research was the eighth grade students in academic year 2018-2019. There were 65 students spread in 3 classes ( VIII.1, VIII.2, and VIII.3) and each class consist appropriately 20-22 students. The researcher took simple random and chose VIII.2 as the representative and the number of total sample is 21 students. The data of the research were collected by using two kinds of instruments, namely reading comprehension test and questionnaire. Reading test was used to obtain data of the students’ reading comprehension ability and questionnaire was used to know the students interest in Reading Comprehension by using Humor Story. The result of data analysis showed that there was significant difference between the students’ score after they were taught by using Humor Story and before they were taught by Humor Story. It was proved by the mean score of the post-test which was higher than the mean score of pre-test (57.57>40.33). Furthermore, the result of the p-value (0.000) was lower than level of significant (α = 0.05); which means that H1 was accepted.  Then, the analysis of interest by using Likert Scale indicated that teacing reading comprehension by using humor story, the students were interested. It was proved by 57% students who were strongly interested, 33% students who were interested and 10% students who were moderate. Based on data analysis, the research concluded that: (1) the use of Humor Story effective in improves students’ reading comprehension; (2) the use of Humor Story makes the students interested to learn reading comprehension
ENGAGEMENT SYSTEM IN SYLLABUS OF SAME-SEX MARRIAGE LEGAL DOCUMENT OF THE UNITED STATES: A SYSTEMIC FUNCTIONAL LINGUISTICS
Authors: Ulfah Ayu Pratiwi , Sujatna Eva Tuckyta Sari , Amalia Rosaria Mita
Published: August 2022

Supreme Court of the United States ruled that the American Constitution guarantee the same-sex marriage in 2015. It is the syllabus of Same-Sex Marriage in the United States that become the object of the research. This research aims to identify the engagement devices and examines how engagement system in the syllabus of same-sex marriage legal document of the United States that indicates the meaning and relation with the readers. The theory proposed by Martin and White of engagement system (2005) based on appraisal system is used to support the analysis. From the analysis, the researcher found there are 116 heteroglossic and 37 monoglossic types from 153 clauses. The presence of heteroglossic as the most type indicates that the petitioners not only made themselves as references or data sources, but also they tried to add many references and other brackets as data and facts that strengthen their statements. In addition, the presence of 'pronounce' type as the most type in heteroglossic as contract shows that the petitioners made many straightforward and assertive statements. These statements are representative of the assured feeling of the petitioners after seeing the fact that the same-sex marriage was discriminated. The presence of 'entertain' type as the most type in heteroglossic as expand shows us that the petitioners support same-sex marriages so that their rights can be recognized in the United States. Petitioners attest the ideals life of same-sex marriages who will be peaceful and prosperous like the hetero-sex marriages. Because they believe that marriage is fundamental right for all citizen.
A Study on Students’ Adversity Quotient and Academic Performance in English Subject
Authors: Kuhon Fiola
Published: August 2022

ABSTRACT

The aim of this study is to observe students’ Adversity Quotient and their Academic Performance, in this case English subject. From many previous studies, there is a high indication that Adversity Quotient plays an important role in students’ academic performance. Therefore, this study was carried out to observe that hypothesis. Quantitative method was used wherefore the data was in form of numbers, namely from Adversity Quotient test and students’ final grade in English class. The findings showed that majority of the students who exceled in academic performance were the students whose test results showed that they were classified with high level of Adversity Quotient. Furthermore, as this study included 2 groups of students, the data depicted that the adult students performed a better result in AQ test than the fresh graduate students who were both in the same semester.

Keywords:

ABSTRACT

The aim of this study is to observe students’ Adversity Quotient and their Academic Performance, in this case English subject. From many previous studies, there is a high indication that Adversity Quotient plays an important role in students’ academic performance. Therefore, this study was carried out to observe that hypothesis. Quantitative method was used wherefore the data was in form of numbers, namely from Adversity Quotient test and students’ final grade in English class. The findings showed that majority of the students who exceled in academic performance were the students whose test results showed that they were classified with high level of Adversity Quotient. Furthermore, as this study included 2 groups of students, the data depicted that the adult students performed a better result in AQ test than the fresh graduate students who were both in the same semester.

Keywords: Adversity Quotient, Academic Performance, Students
THE AMBIVALENCE OF MAIN CHARACTER IN DIVAKARUNI’S THE MISTRESS OF SPICES
Authors: Rosida Ana , Petrina Petrina
Published: August 2022

This article analyzed of the ambivalence of the main character in the novel The Mistress of Spices by Chitra Banerjee Divakaruni by using post colonial theory from Bhabha concept that ambivalence, mimicry and hybridity. The purposes of this research were describing the cause of ambivalence by the main character and also to describe mimicry and hybridity potrayed by Tilo as the main character in Divakaruni’s The Mistress of Spices. The method of this research was descriptive qualitative methods to described the answer from the problem formulation. The source of the data of this research was the novel The Mistress of Spices by Chitra Banerjee Divakaruni which was published in 1997 and consists of 15 chapters and 317 pages. And, the instrument of this research was note taking. The technique of data analysis of this research was linked to the theory, concept and method. The result found that the main character face the ambivalence because of her rules and love. Living in America is greatly influenced her on the new culture of imitating and hybridizing about American culture.
Organ Donation in Romanian Online Media
Authors: Petre Oana Alexandra , Băban Adriana
Published: August 2022

Mass media represents the primary source of information about organ donation for the general public. The present study explored the content of Romanian online media concerning organ donation. We conducted a content analysis of 313 media materials published online between October 2012 and October 2019 in Romanian. The coding categories were year of publication, media outlet, type of material, type of evidence, valence, topic, and proximity of the story. A semestral web-search was conducted between February 2016 and November 2019. The analysis revealed that the Romanian online coverage of organ donation was modest across time. Regarding the valence, results indicated that 57.2% of the materials presented organ donation in a positive way, 14.1% were neutral, 12.5% were negative, whereas 16.3% of the materials were mixed. Moreover, the valence of the materials varied across media outlets, proximity of the story and publication year. Promotion, information about organ donation and system were the topics that occurred most frequently, followed by events, policy, and legal categories. Findings provide insight into how media may shape people's opinions about organ donation. The study also contributes to understanding the Romanian organ donation macro-social environment and provides valuable information for practice.
The Effects of Malaysian Older People’s Participation and Engagement in the Local Labour Market
Authors: Ramely Aslinda , Ahmad Yarina , Mohamed Harith Nor Hafizah
Published: August 2022

Given the increasing rise of the world's older population and the quick alteration of the socioeconomic landscape, many countries, Malaysia included, recognise the necessity to protect the economic security of the older people. This country's alarmingly ageing population will transform it into an aged nation by the year 2030. However, several issues and challenges experienced by them, such as the inadequacy of financial savings, living in poverty, and being censured by family issues, may prevent Malaysia from attaining its 2020 ambition of becoming a developed nation and aged friendly country. Thus, this study believed it was necessary to implement effective methods to tackle these issues and challenges along with maximising the health and wellness of the older population. One alternate approach proposed by this study is to increase the participation of healthy and capable older people in the labour force. Therefore, the purpose of this study is to examine the effects of labour force participation and engagement on older people, their family members, society, and the country in support of the alternate approach proposed. Following this aim, this study obtained the data from qualitative research for the doctoral degree of one of the authors. This study found that older people's employment favourably impacted themselves on (i) an individual level, (ii) their families and coworkers on an interpersonal level, and (iii) society on a societal level. This study also demonstrates that the employment of older people can positively impact the (iv) country. The majority of the positive impacts on older people's employment can contribute to their wellbeing, as outlined in the National Policy for Older Person (2011).
Limites dos Sistemas Liberais Frente ao Crescimento de Lideranças Políticas Extremistas no Início do Século XXI
Authors: Meira Júlio Cesar
Published: August 2022

O início do século XXI tem sido marcado pela ascensão de governos com colorações autoritárias em vários países ocidentais, do leste Europeu às Américas. Partimos de uma análise da hipótese central da obra “Como as Democracias Morrem”, de Levitsky e Ziblatt (2018), que ao testemunhar a chegada ao poder de Donald Trump, um outsider na política tradicional norte-americana, apontam a necessidade de reforçar os filtros partidários para impedir as candidaturas com graus variados de conteúdos fascistóides, autoritários e demagógicos, em seu nascedouro, para refletir sobre a incapacidade de as instituições da democracia liberal compreender e atender as demandas de seus cidadãos, contribuindo para o florescimento de sentimentos de insatisfação generalizada, da ampliação do fosso da desigualdade social e da sensação de expectadores de um processo para o qual os cidadãos não tem participação. Buscamos demonstrar que a receita de aprofundamento dos mecanismos de controle institucional da democracia liberal não é a resposta neste momento de “crise dos mapas ideológicos”.
Foi mesmo a agricultura a grande revolução do neolítico?
Authors: Simas de Aguiar Rodrigo Luiz
Published: August 2022

Durante décadas persistiu nas bancadas escolares a ideia de que a agricultura foi a grande revolução do neolítico, que permitiu a emergência de complexidade social e a formação das sociedades clânicas. Esta noção, surgida no século XIX, teve especial impulso a partir da década de 1950 com Gordon Child e persistiu ao londo do século XX. Contudo, novas descobertas arqueológicas demandam uma revisão deste pressuposto teórico, forçando-nos a repensar até mesmo as tradicionais noções de sedentarismo e nomadismo.
Simulation of Combined Stresses and Stress Concentration Factor Effects on a Femur Cortical Bones
Authors: Velez-Cruz Alex J.
Published: August 2022

The purposes of this article were to obtain mechanical properties of the dry femur cortical bone samples through a tensile load and stress concentration factor approach and to provide simulations to predict experimental behaviors based on manipulations of certain properties and parameters of the biomaterial. Since bone samples have characteristics and geometries, the development of a mathematical model was necessary to describe the combination of stresses interacting in the bone when a tension load is applied. The samples have average diameters and lengths of 0.5 and 2 inches respectively and were tested using a 10 kN Universal Tensile Machine to determine mechanical properties such as yield and ultimate stress, young module, and fracture, among others. Several simulations were conducted to evaluate failure criteria like “Von Mises”, “Tresca” and “Tsai-Wu”. Finally, was concluded that 83% of the data obtained from the 22 samples observed in the “Stress-Strain” charts showed a directly proportional relationship.
Historical analysis of water pollution in the Portoviejo River
Authors: Guambo Gonzalo , Torres Julio , Quiroz Santiago
Published: August 2022

The river Portoviejo crosses four cantons of the province of Manabí and is the main source of water for the inhabitants of the area to be used in various uses. The objective of this bibliographic review article is to carry out a historical analysis of the water pollution of the Portoviejo River. The qualitative and descriptive documentary research methodology was used. The authors conclude that the factors that influence the pollution of the Portoviejo River are the constant direct discharges of wastewater and solid waste along its route by the residents of the area and the contribution of the water treatment plant waste from the area.
Biochemical and immunological markers of the adaptive response in olfacto-odorimetric studies
Authors: Khripach Ludmila V. , Budarina Olga V. , Knyazeva Tatiyana D. , Makovetskaya Anna K. , Koganova Zoya I. , Andryushin Ilya B.
Published: August 2022

The purpose of the study is to determine whether exposure to odours of model food odourants can lead to a change in biochemical and immunological parameters that we previously used when examining the population in the area of food industry enterprises location using the method of quantitative olfacto-odorimetry. Methods. The specified concentrations of aerosols of three food flavours (orange, cognac and coffee) were supplied to the participants of the studies with a help of ECOMA T08 olfactometer. Quantitative composition of the aerosols was controlled by GC/MS. In participants saliva samples taken before, during and at the end of each experiment, the intensity of luminol-dependent chemiluminescence, the content of secretory IgA, IL-1β, IL-6 and IL-8, the activity of α-amylase and N-acetyl-β-D-glucosaminidase were determined. For data analysis, paired Friedman and Wilcoxon tests were used with Bonferroni correction for the problem of multiple comparisons. Results. A reliable effect of the smell of food odourants was found on one indicator only - the activity of salivary α-amylase - when combining data from 5 separate experiments (n=45): 93.3[24.3;160.0] U/ml at the end of the experiments against background values of 109.9 [42.5; 216.7] U/ml;, p=0.0096 with a significance level of p=0.05/3=0.017. A decrease in the average values of salivary α-amylase activity was shown to hide opposite changes in individual values: an increase in activity in people with low background values (below the median of the initial distribution) and an amplitude-dominant decrease - in people with high background values (above median). The revealed phenotypic polymorphism of α-amylase regulation contributes to one of relevant Post-COVID areas - the study of the ability of people to perceive odours and react to them. Limitations. The use of olfacto-odorimetry to study effect of odours on human health indicators is promising, but requires design of protocols with extended exposure time. Conclusion. A decrease in average values of salivary α-amylase activity with distinctive forestall of the upper quartile may be a sign of human reflex re sponse to the emission of odourous substances in the areas of food industry.
Physical rehabilitation of patients with occupational diseases of the knee joints and industrial injuries
Authors: Filimonov Sergey N. , Gordeeva Raisa V. , Kuzmenko Olga V. , Povarnitsina Natalya V. , Semenova Elena A. , Logunova Tatyana D.
Published: August 2022

Introduction. The results of the use of therapeutic exercises in the form of Nordic walking in the patients with industrial injuries and occupational diseases of the knee joints are submitted. Studies have shown that Nordic walking helps to restore the range of motion in the affected joints, reduces the severity of pain syndrome, and has a positive effect on the cardiovascular and respiratory systems. Materials and methods. During the rehabilitation of the patients with industrial injuries and occupational diseases of the knee joints, therapeutic exercises were prescribed in the form of Nordic walking in the conditions of terrenkur against the background of high aeronization of the air environment. A control group of the patients with a similar pathology underwent rehabilitation using training devices for Continuous Passive Motion (CPM)-therapy in the hall for therapeutic exercises of the rehabilitation center. Upon admission and before discharge from the center, the volume of movements in the knee joints was examined, muscle strength, respiratory rate and heart rate, arterial blood pressure level were determined, pulse oximetry was performed, and the adaptive response was evaluated according to L.Kh. Garkavi. Results. The use of therapeutic exercises in the form of Nordic walking in the open air in the patients with industrial injuries and occupational diseases of the knee joints showed similar results with rehabilitation in closed halls, which makes it possible to use this technique instead of indoor activities. Limitations. The study did not include patients with other occupational pathology, as well as those who did not give informed consent to this study. Conclusions. The method of therapeutic exercises in the form of Nordic walking in the open air has shown similar effectiveness with the CPM-method in closed halls, which allows it to be preferred in rehabilitation programs for the patients with industrial injuries and occupational diseases of the knee joints in the conditions of the COVID-19 pandemic.
Emotional burnout syndrome and mental health indices in the coal industry workers
Authors: Vlakh Nadezhda I. , Danilov Igor P. , Gugushvili Maksim A. , Paneva Nataliya Ya. , Logunova Tatyana D.
Published: August 2022

Introduction. Emotional burnout is a condition common among workers of “assisting” occupations. In workers of the main professions in the coal industry, the frequency of emotional burnout has not been studied enough, especially in terms of its relationship with mental health indices: the presence of sub-depression, negative affectivity, and social inhibition. The purpose of the survey was studying the prevalence of emotional burnout syndrome and its relationship with the development of sub-depression, negative affectivity and social inhibition in the coal industry workers with occupational diseases. Materials and methods. Two hundred forty seven miners with occupational diseases (dust lung pathology, diseases of the musculoskeletal system, vibration disease) were examined using questionnaires (DS14, by V.V. Boyko, and N.I. Vlakh). Results. 38.9% of the workers had emotional burnout syndrome. A reliable relationship between the emotional burnout syndrome and the development of sub-depression, negative affectivity and social inhibition was determined. Limitations. The survey is limited to a sample of 247 miners with occupational diseases examined using questionnaires (DS14, by V.V. Boyko, and N.I. Vlakh). Conclusion. Coal industry workers are subject to developing emotional burnout syndrome, the prevalence of which is 38.9%. The emotional burnout syndrome is interrelated with the development of sub-depression, negative affectivity and social inhibition, the incidence of which reaches a maximum in the exhaustion phase of burnout.
Experimental models of vibration disease (literature review)
Authors: Zhukova Anna G. , Kizichenko Natalya V. , Gorokhova Larisa G. , Kazitskaya Anastasiya S.
Published: August 2022

Introduction. Long-term vibration exposure to the human body is a risk factor for the development of occupational diseases and comorbid conditions causing, first of all, the pathology of the nervous system, as well as the cardiovascular, gastrointestinal tract and musculoskeletal systems. Pathogenetic aspects of vibration exposure at the molecular level remain open and require the search for adequate experimental animal models. The review describes experimental methods for studying vibration disease. A literature search was conducted in the databases MedLine, PubMed, Web of Science, Scopus, Google Scholar, CyberLeninka and RSCI. The results of experimental studies differ due to the difference in frequencies and duration of vibration exposure. Sanitary and hygienic characteristics of workplaces of coal-mining enterprises in Kuzbass. Data are given at the levels of local and whole-body vibration at the workplaces of an underground sinker, a stope miner, and a mining machine operator. Experimental modelling of local and whole-body vibration. Experimental methods of vibration exposure to laboratory rats, mice and rabbits at the local and whole-body levels are described. The presented experimental models are as close as possible to real vibration effects in production conditions. Vibration at frequencies above 4 Hz has been shown to cause changes in the structure and functions of peripheral vessels and nerves, along with hypoxic damage of the brain, heart, kidneys, liver, and skeletal muscles. Conclusion. Experimental modelling of vibration disease makes it possible to study the organ-specific molecular mechanisms of damaging vibration exposure to the body and develop effective preventive and therapeutic measures.
Awareness about depressive conditions, methods of their prevention and correction in adolescents
Authors: Bobrisheva-Pushkina Natalia D. , Kuznetsova Lubov Yu. , Popova Olga L. , Denisova Elena L. , Nikitenko Elena I. , Kirpichenkova Ekaterina V. , Petrova Ekaterina S. , Korolev Aleksei A.
Published: August 2022

Background. According to WHO, there is an increase of depressive disorders in all age groups. The risk group of depression is adolescents, the risk factor is the low level of knowledge about it. The aim was to study the prevalence of depressive states, the level of literacy about depression among schoolchildren for improving educational programs. Materials and methods. An anonymous voluntary survey was conducted in two stages with an interval of 4 years in the Moscow region among students in grades 8-11 of educational institutions. At the first stage, three hundred twenty-four respondents were interviewed, at the second stage - 251 one. The severity of depression was assessed using the hospital anxiety and depression scale (HADS), with the help of the questionnaire the level of depression literacy was studied. Statistical processing was carried out with the calculation of relative risk values, reliability of differences (with a probability degree of more than 0.95) using Microsoft Excel 365. Results. The prevalence of depression in 2014 was 20.4%, in 2018 - 21.1%. During the observation the number of students who believe that nothing should be done in the case of depressive symptoms has significantly decreased, the number of students who are ready to visit a psychologist has significantly increased, the number of schoolchildren who were willing to see a medical doctor and who consider self-treatment possible has not changed. The main source of knowledge remains the Internet, help from the professional community is underused. Discussing mood problems with others and using physical activity turned out to be effective for self-corrected depressive states. Limitations. The study has age (14-17years), regional and educational (students of schools) restrictions. Conclusions. Revealed high prevalence of depressive manifestations among schoolchildren and their insufficient knowledge requires correction of educational programs and regular monitoring of their awareness.
Association of HIF-1A (rs11549465) gene polymorphism with congenital malformations and intrauterine growth retardation of the fetus
Authors: Gulyaeva Olga N. , Kazitskaya Anastasiya S. , Zhukova Anna G. , Zagorodnikova Olga A. , Alekseeva Marina V. , Renge Lyudmila V.
Published: August 2022

Introduction. Congenital malformations have long received the status of a marker of environmental distress. Six per cent of the newborns in the world are diagnosed with congenital malformations of various etiologies, 30 million develop intrauterine growth retardation, often associated with hypoxia, while the number of these pathologies is significantly higher in environmentally unfavourable regions. The degree of resistance to hypoxia is determined by the transcription factor induced by hypoxic conditions - HIF. There is revealed polymorphism of the HIF gene, which determines the differences in the activity of the transcription factor encoded by this gene, and therefore, the differences in the level of resistance to hypoxia. Recently, HIF has also been detected in response to the activation of free radical processes. Materials and methods. The study examined fifty five women living in the South of Kuzbass, most of them in the city of Novokuznetsk. 18 women were included in the control group because they carried a healthy child, the study group consisted of 11 women who gave birth to children with intrauterine growth retardation, and 26 women who gave birth to children with congenital malformations. Genomic DNA was isolated from peripheral blood leukocytes using the phenol-chloroform extraction method. Gene typing was carried out by the Real Time method. Results. Among the studied groups, in women who gave birth to children with congenital malformations, there were no reliable differences in the occurrence of polymorphisms of mutant and wild types. In the group of women who gave birth to children with intrauterine growth retardation, a reliable association of C/T polymorphism in the mother with intrauterine fetal growth retardation was shown (χ2 = 4.54; OR = 9.71), while the ancestral form of C/C was associated with resistance to this pathology. Limitations. Since the identification of the association of the HIF-1A (rs11549465) gene polymorphism with intrauterine growth retardation was of a pilot nature, it is advisable to increase the sample. Conclusion. The results obtained may indicate the leading role of the HIF-α subunit in the body’s adaptation to hypoxia and the secondary importance of this protein in the regulation of pro- and antioxidant balance.
Evaluation of the genotoxicity of the food dye tartrazine in a micronucleus test in vivo
Authors: Akhaltseva Lyudmila V. , Yurchenko Valentina V. , Yurtseva Nadezda A. , Konyashkina Mariya A.
Published: August 2022

Introduction. Food azo dye Tartrazine (E102) is widely used in the production of food, pharmacological and cosmetic products. Despite the approval for use, interest in a comprehensive assessment of the impact of food colours, especially synthetic ones, on health continues unabated. The analysis of literature evaluating the genotoxicity of Tartrazine in vivo studies revealed some inconsistencies in the results, that showed the possibility to test a retail food colouring in one of recommended tests. Materials and methods. The Tartrazine genotoxicity (produced in India, purity 88.37%) was studied in the micronucleus test on male mouse bone marrow cells (hybrids F1 CBA x C57Bl6/j). The test substance was double enteral administrated in the dose range 250-2000 mg/kg. The frequency of polychromatophilic erythrocytes (PCEs) with micronuclei (MNs) was estimated by the analysis of 4000 PCEs. The proportion of PCE among all erythrocytes was determined by analyzing 1000 cells per animal. Results. There was no increase in the frequency of micronucleated polychromatophilic erythrocytes over a concurrent negative control with double enteral administration of Tartrazine in all doses studied. The proportion of PCEs among all erythrocytes did not change. Limitations of the study are due to the methodology of the test: only cytogenetic disorders in a single tissue were analyzed under conditions of double enteral administration of the studied sample. Conclusion. The sample of the food dye Tartrazine (E 102) in the dose range of 250-2000 mg/kg did not show cytogenetic activity in the in vivo micronucleus test on mouse bone marrow cells after a double enteral administration.
Comparative evaluation of mathematical models for predicting acute toxicity of chemicals
Authors: Guseva Ekaterina A. , Nikolayeva Natalia I. , Filin Andrey S. , Savostikova Olga N.
Published: August 2022

Introduction. Considerable attention is paid to the assessment of acute toxicity of chemical compounds during oral administration due to the different rates of absorption of substances in different animal species and various experimental conditions. Given the pace of development of the chemical industry, researchers are faced with the question of accelerating the study of the properties of substances and filling data gaps. Therefore, quantitative prediction of the toxic properties of substances using mathematical models based on the structure or structural properties of compounds - quantitative structure -activity relationship (QSAR) modeling - is one of the promising areas. The purpose of this study is to create and compare the performance of the obtained mathematical models for predicting the acute toxicity of various classes of chemicals. Materials and methods. The study included four classes of pesticides (organochlorine compounds (OCs), azoles, carbamates, organophosphorus compounds (OPs) in the amount of 100 compounds with descriptors calculated by PaDEL-Descriptors software ver. 2.21. Regression models were constructed in the WEKA software, subjected to an internal validation procedure. Statistical parameters such as the mean square error (RMSE) and the coefficient of determination (r 2) were used to assess the quality of regression models. Results. To predict acute oral toxicity of OCs and OPs, it is optimal to use a model in which neural networks and the support vector method are combined, for carbamates - an ensemble model that includes linear regression and the support vector method. For substances from the azole group, it was not possible to create a model that would meet the necessary requirements: r 2>0.6 for the training set and r 2 >0.5 for cross-validation. Limitations. The study is limited by the number of compounds studied, the class of chemical compounds, and the area of distribution of the results obtained during modeling. Conclusion. In this study, ensemble modelling methods demonstrated the best results in predicting acute oral toxicity for OCs, carbamates, and OPs.
Experimental study of toxic properties of a lead-tin-selenium-tellurium solid solution
Authors: Nikolayeva Natalia I. , Filin Andrey S. , Guseva Ekaterina A. , Ivanova Lubov G.
Published: August 2022

Introduction. Solid solutions are widely used in the manufacture of particularly sensitive and high-precision devices, various kinds of sensors and energy converters, which causes a large number of workers to come into contact with them. The purpose of the study: to conduct experimental research and estimate biological effect of a solid lead-tin-selenium-tellurium (LTST) solution on warm-blooded animals. Materials and methods. Solid solution (lead (52%), tin (8%), selenium (trace) and tellurium (40%) - powder insoluble in water. Experiments were carried out on mice, rats and rabbits. Acute and chronic toxicity, cumulative properties, fibrogenic activity, irritant effect on skin and mucous membranes were evaluated. Results. According to the parameters of acute toxicity LTST is a low-hazard compound (Hazard Class 4), it has an irritant effect on skin and mucous membranes, the expressed cumulative properties (Kcum - 2.58). General toxic effect of the alloy is characterized by changes in functional state of kidneys, hematopoietic function, blood coagulation system. The compound has a moderately pronounced fibrogenic effect. Limitations. The limitation of this study is the lack of literature data of toxicological studies on the biological effect of a solid solution of LTST was the basis for its study. Conclusions. The biological effect of a solid solution of LTST on the organism was studied for the first time on models of acute, subacute and chronic experiments. According to GOST 12.1.077-76 LTST belongs to Hazard Class 4 (low-hazardous compound).The solid solution has been established to belong to compounds which may cause acute inhalation poisoning (Limac - 46.73 mg/m3). LTST is dangerous in terms of the development of chronic intoxication, has pronounced cumulative properties (Kcum - 2.58). LTST has a general toxic effect, leads to disruption of hematopoietic function, increased content of coproporferin in urine, which is associated to a large extent with the presence of lead molecule in the solution. The solid solution causes the development of a fibrotic process of pulmonary tissue. LTST is less toxic than the lead in its composition. Control over the concentration of LTST in the air of the working area should be carried out according to the MPC = 0.05 mg/m3 (lead and its inorganic compounds).
Hospital Information System for Decision Making: A Qualitative Study
Authors: Mohamed Mussa Suliman
Published: August 2022

Abstract: Background: Information technology applications play a major role in improving the services provided to patients in healthcare settings. Hospital Information System HIS is expected to facilitate information management and decision making, thus enhancing patient services. Purpose of this study is to explore the obstacles that healthcare practitioners in PKU Muhammadiyah Bantul Hospital faces during using HIS for decision making. Method: This research is a qualitative study. Depth-interviews were carried out with six respondents (Two Clinicians, Three Managers, and One Director), interviews were recorded and transcribed for analysis, a list of codes has produced representing themes identified in the textual data. Results: Data in the HIS were not optimal due to the insufficiency of the system in generating the necessary information for decision-making. Raw data, not real time data, unstable connection, and incomplete data between units were the most obstacles that decision makers faced. Conclusion: One of the crucial keys of a good performance of healthcare providers is hospital information system that ensures the production, analysis, and providing a reliable and timely information, making it easy for managers and doctors to make managerial and clinical decisions more effectively. Upgrading HIS to enable data analysis is suggested.

 

Keywords: Hospital Information System, Obstacles, Decision Making.
An Investigation of Changes in Hospital Emergency Room during the Era of Covid-19 Outbreak: An Analysis of Literature Review
Authors: Murnani Sari
Published: August 2022

The frontline of hospital in providing health services related to Covid-19 outbreak is the Emergency Room (ER), so that it comes as a high-risk place for Covid-19 transmission among patients and patients as well as patients and health workers in the medical context. To prevent the transmission, several changes should be done in ER during Covid-19 pandemic. Besides, this research aimed at analyzing the changes made to ER as an effort to prevent and control Covid-19 infection which could be utilized as a recommendation for the ER towards other hospitals during this epidemic disease. The method used in this article was a literature review by researching the design through Google Scholar, Mendeley, and PubMed. The keywords included emergency department, hospital, changes, guidelines, preparedness, and Covid-19. The criteria of selected articles were published in 2020 using full English text, and the type of research was descriptive qualitative research. In addition, the total of the articles were 5 used articles which should match the research criteria related to the topic of the research. Based on the results of the literature reviews from the experts, the changes made to ER during the Covid-19 pandemic were divided into 3 parts such as preparation, pre-triage and during triage. Likewise, the made changes during the preparation consisted of organizational structure and leadership, human resource management, infrastructure, and logistics. Likewise, the changes made during pre-triage were online clinics and patient screening. At last, the change made during triage was in line with the patients’ triage flow.
MENINGKATKAN HASIL BELAJAR SISWA MELALUI TEKHNIK PEMBELAJARAN TOTAL PHYSICAL RESPONSE PADA MATERI WRITING SKILL TEKS INTERAKSI INTERPERSONAL PADA SISWA KELAS VII-B MTSN 1 ACEH BARAT TAHUN AJARAN 2020-2021
Authors: Susanti Nova
Published: August 2022

Salah satu tekhnik pembelajaran yang tepat dalam pembelajaran bahasa inggris adalah Tekhnik Pembelajaran Total Physical Response. TPR (Total Physical Response) merupakan suatu metode pembelajaran bahasa yang disusun pada koordinasi perintah (command), ucapan (speech) dan gerak (action); dan berusaha untuk mengajarkan bahasa melalui aktivitas fisik (motor). Oleh karena itu penelitian ini mengambil judul " Meningkatkan Hasil Belajar Siswa Melalui Tekhnik Pembelajaran Total Physical Response pada Materi Writing Skill Teks Interaksi Interpersonal pada Siswa Kelas VII-B  MTsN 1 Aceh Barat Tahun Ajaran 2020-2021". Metode yang dilakukan dalam penelitian ini adalah metode penelitian tindakan kelas (PTK), Sedangkan intrument pengumpulan data meliputi Observasi dan Dokumentasi. Penelitian ini dilakukan pada kelas VII-B Madrasah Tsanawiyah Negeri 1 Aceh Barat. Hasil observasi aktivitas belajar siswa pada siklus I mencapai 66,25%, mengalami peningkatan pada siklus II menjadi 91,5%. Hasil observasi aktivitas guru pada siklus I mencapai 63,75%, mengalami peningkatan pada siklus II menjadi 88,75%. Sejalan dengan aktivitas belajar siswa yang meningkat maka pembelajaran dengan penerapan Tekhnik Pembelajaran Total Physical Response juga meningkatkan hasil belajar siswa kelas VII-B Madrasah Tsanawiyah Negeri 1 Aceh Barat pada siklus I diperoleh persentase rata-rata pada kategori sedang dengan persentase 75,66 %. Pada siklus II diperoleh hasil peningkatan hasil belajar siswa diperoleh rata-rata pada kategori tinggi yaitu persentase 90%.Sehingga penerapan Tekhnik Pembelajaran Total Physical Response dapat meningkatkan hasil belajar siswa kelas VII-B Madrasah Tsanawiyah Negeri 1 Aceh Barat Tahun Ajaran 2020-2021.
THE IMPLEMENTATION OF THE STUDENT TEAMS ACHIEVEMENT DIVISION (STAD) COOPERATIVE LEARNING MODEL IN IMPROVING STUDENTS’ LEARNING OUTCOMES ON SMALL BALL GAME MATERIALS FOR YEAR VII-A STUDENTS OF MTSN 3 WEST ACEH IN 2020-2021 ACADEMIC YEAR
Authors: Badrussalim Badrussalim , Irawan Riki
Published: August 2022

This study aims "To find out whether the use of the Student Teams Achievement Division (STAD) Cooperative Learning Model can Improve Students’ Learning Outcomes on Small Ball Game Materials for Year VII-A Students of MTsN 3 West Aceh in 2020-2021 academic year. The research sample of this study was Year VII-A class with the total number of students was 23 students. This study used Classroom Action Research (CAR) with the methods of observation, data collection, tests, documentation and data analysis. This study used two cycles to determine the learning outcomes of the students using Student Teams Achievement Division (STAD) type of cooperative learning model in small ball game material. The results of this study indicated that the Student Teams Achievement Division (STAD) type of cooperative learning model can improve students’ learning outcomes in small ball game material for year VII-A students of  MTsN 3 West Aceh in 2020-2021 academic year. From the data obtained, the percentage of the learning outcomes on the small ball game material in the first cycle of classical completeness was 47.82%, and in the second cycle was 82.60%. This meant that there was an increase in completeness, namely 5 students (15.63%). Based on the achievement of the  students’ activity that was 86.66%, it can be said that the learning outcomes on the small ball game material with the Student Teams Achievement Division (STAD) type cooperative learning model in cycle II was successful because the results obtained have exceeded the students’ learning mastery indicator, which is 80 %.
PENERAPAN MEDIA KIDOODLE DALAM MENINGKATKAN KETERAMPILAN MENYIMAK CERITA ANAK
Authors: Rosida Sisi , Bangun Meilyana Putri
Published: August 2022

Perkembangan teknologi menyediakan berbagai fasilitas untuk belajar. Salah satunya media pembelajaran melalui aplikasi digital sebagai wadah pembelajaran inovatif dan kreatif. Penelitian ini bertujuan untuk menjelaskan proses dan hasil penerapan media kidoodle dalam meningkatkan keterampilan menyimak cerita anak pada siswa kelas IV YPI Amir Hamzah. Penelitian ini adalah penelitian tindakan yang bertahap 2 siklus, meliputi: tahap perencanaan, pelaksanaan, observasi, dan refleksi. Pengumpulan data dengan observasi, catatan lapangan, dan tes.  Analisis data penelitian dilakukan secara kualitatif, dianalisis dari hasil observasi dan catatan lapangan. Adapun temuan penelitian: (1) adanya peningkatan keterampilan siswa dalam menyimak cerita anak pada proses penerapan media kidoodle pada struktur cerita anak, dan (2) Peningkatan ketuntasan belajar siswa dibuktikan pada siklus I dengan nilai rata-rata hanya 66, meningkat menjadi 89,4. Hal ini menunjukkan media kidoodle memberikan dampak positif dalam peningkatan keterampilan menyimak cerita anak.