bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis and In Silico Molecular Docking Studies on Substituted Piperic Acid Derivatives as Inhibitors of Bacterial DNA Gyrase
Authors: Chopra Bhawna , Dhingra Ashwani K. , Prasad Deo N. , Bhardwaj Sakshi , Dubey Sonal
Published: July 2019

Background:

Piperine or piperic acid was isolated from fruits of Piper nigrum and had been reported as pharmacological valuable bioactive constituents. Keeping in view, a series of piperic acid-based N heterocyclic’s derivatives were synthesized and evaluated for antibacterial activity. All these prepared ligands were docked to study the molecular interactions and binding affinities against the protein PDB ID: 5 CDP.

Objective:

To meet the real need of newer antibacterials, we designed and synthesized scaffolds with good antibacterial activity. The obtained antibacterials have been validated in terms of ligand-protein interaction and thus prove to build up as good drug candidates.

Methods:

Antibacterial activity of the compounds were carried out against bacterial strains; three Grampositive and three Gram-negative bacterial strains using agar well diffusion method. In silico molecular docking studies were carried out using Glide (grid-based ligand docking) program incorporated in the Schrödinger molecular modeling package by Maestro 11.0.

Results:

Compounds BC 28, BC 32, and BC 33 exhibits antibacterial activity along with Glide docking score of -8.580, -9.753 kcal/mol, and -8.813 kcal/mol, respectively. Docking studies explained hydrogen bonding, pi-pi, and hydrophobic interactions with amino acid residues which explain the binding affinity of the most docked ligand with protein.

Conclusion:

In the present study, substituted piperic acid was synthesized and evaluated as antibacterial compared with standard drug ciprofloxacin and results interpret that having nitrogen as heteroatom in the heterocyclic nucleus found to be more potent than the standard drug ciprofloxacin. On comparing, substitution with electron-donating groups generates excellent antibacterial potential against the bacterial strains. It was also proved that having substitution with electron-donating groups on meta and para position with triazoline ring system exhibits greater potential while compounds which have a meta- electron-donating substituent showed lesser activity with thiazole nucleus. In addition, structure-based activities of the prepared analogs were discussed under Structure-Activity Relationship (SAR) section.
Influence of Betaine- and Choline-based Eutectic Solvents on Lipase Activity
Authors: Ribeiro Bernardo Dias , de Carvalho Iff Lucas , Coelho Maria Alice Zarur , Marrucho Isabel M.
Published: July 2019

Background:

Eutectic solvents are a mixture of two compounds which possess a lower
melting temperature than the parent compounds, using quaternary ammonium salts, such as choline
chloride and betaine hydrochloride and organic acids, polyols and amides as hydrogen bond donors.
These solvents can be an alternative as non-aqueous media for enzymatic reactions, mainly using lipases.

Objective:

The objective of this work is to evaluate enzymatic activity and stability of commercial lipases,
immobilized or at free form (Thermomyces lanuginosus: Lipozyme TL IM, iTL and Lipolase
100 L, fTL; Candida antarctica: Novozym 435, iCALB; Novozym 735, iCALA and Novozym CALB
L, fCALB); and a phospholipase (Lecitase Ultra), in the presence of eutectic solvents (choline chloride
ChCl:urea, ChCl:glycerol, betaine hydrochloride (BeHCl):urea and BeHCl: glycerol.

Methods:

Initially, lipases were maintained for 2 hours in solutions of choline and betaine-based
eutectic solvents (1 to 20% m/m) at 25ºC compared with water for relative enzymatic activity. Using
the solvent that best promoted lipase activity, some parameters were evaluated such as the molar ratio
between quaternary ammonium salts and urea, stocking temperature and kinetics.

Results and Conclusion:

These eutectic solvents enable, mainly with immobilized lipases, 25 to 125
times more activity than water at 25ºC and 2h, and even after 24h, lipase iTLL was still 40 times more
active in the presence of ChCl:Urea 1:3. Lipase iCALB showed great thermostability 47 times higher
at 55ºC, almost double relative activity at 25ºC in the presence of BetHCl:Urea 1:4.
Clustering Algorithm for Community Detection in Complex Network: A Comprehensive Review
Authors: Agrawal Smita , Patel Atul
Published: July 2019

Many real-world social networks exist in the form of a complex network, which includes
very large scale networks with structured or unstructured data and a set of graphs. This complex
network is available in the form of brain graph, protein structure, food web, transportation system,
World Wide Web, and these networks are sparsely connected, and most of the subgraphs are densely
connected. Due to the scaling of large scale graphs, efficient way for graph generation, complexity,
the dynamic nature of graphs, and community detection are challenging tasks. From large scale
graph to find the densely connected subgraph from the complex network, various community detection
algorithms using clustering techniques are discussed here. In this paper, we discussed the taxonomy
of various community detection algorithms like Structural Clustering Algorithm for Networks
(SCAN), Structural-Attribute based Cluster (SA-cluster), Community Detection based on Hierarchical
Clustering (CDHC), etc. In this comprehensive review, we provide a classification of community
detection algorithm based on their approach, dataset used for the existing algorithm for experimental
study and measure to evaluate them. In the end, insights into the future scope and research
opportunities for community detection are discussed.
ORGANIZATION OF MONITORING OF QUALITY OF INNOVATION PROCESSES IN ENTERPRISES OF ELECTRONIC INDUSTRY
Authors: Gulevitskij A. Yu. , Kurlov A. V. , Kurlov V. V.
Published: July 2019

This article focuses on the decision of problems of increase of efficiency of introduction of innovation in industrial enterprise. The publication includes a description of the author’s approach to innovation in the industrial enterprise, implemented in the form of a database. The main functions of the database are divided into two main stages – preparatory and informative. The functions of the preparatory stage include the collection of information about the industrial enterprise, the rationale for the choice of innovation, determination of the composition and administration of training (retraining), justification of the technical appearance of innovation. At the supporting stage, the database allows information support in the development and implementation of innovations in terms of timing, volume and costs, to carry out a priori and a posteriori evaluation of the quality of innovation on the basis of situational norms, as well as support for decision-making on innovation management in the industrial enterprise. The database is based on the theory of system analysis, the basic principles of the theory of innovation, methods of situational modeling, graph theory and probability theory. The results of the developed database can be used by modern industrial enterprises in the implementation of innovations.
ESTIMATION OF STRUCTURAL SIMILARITY FOR CONTROL OF MICROELECTRONIC PRODUCTS
Authors: Gusman Yu. A. , Pichugin Yu. A. , Smirnov A. O.
Published: July 2019

In this paper we consider the technological process of manufacturing micromechanical gyroscopes, the output of which is divided into cells of the crystal plate and each cell contains a fixed number of product elements. The estimation of structural similarity for measurements of technical characteristics of various devices is offered. A relatively large value of structural similarity assessment means that there is a dependence of the quality of the manufactured devices on the position on the crystal plate. This gives a good reason for further work to improve the quality of the process or to change the technological scheme as a whole. The article considers a numerical example based on a real sample of microelectronic products. The proposed method can be used both in the process of adjustment of the production process and in the rejection of products, when further configuration of the equipment is no longer possible.
CALCULATION OF FORCES FORCING VIBRATION IN A PLANETARY GEAR
Authors: Golubkov V. A. , Shishlakov V. F. , Fedorenko A. G. , Vataeva E. Yu.
Published: July 2019

Most electromechanical devices contain planetary gears. Vibration is the result of the interaction of the teeth and is largely determined by the accuracy of the manufacture of their profile and the error of the step at the production stage, as well as the defects arising in the course of operation. The main elements influencing the vibration of the gears of the planetary gearbox are the deviation of the tooth profiles from the involute and the error in cutting the gear teeth. To reduce the dynamic loads in the contact areas and improve the reliability of gearing, these errors should be monitored and normalized in the allowable range. Based on the analysis of the elastic forces arising in the contact of the teeth, we obtain expressions for the contact stiffnesses and the forces forcing the vibration of the gears. Elastic forces are determined by identifying the deformations that occur at the contact of the gear and wheel teeth. The article describes an analytical description of the spectral composition of the forces that compel vibration, depending on the profile errors and the pitch of the gears of the planetary gear.
Assessing personality across 13 countries using the California Adult Q-set
Authors: Gardiner Gwendolyn , Guillaume Esther , Stauner Nick , Bae Jaechang , Han Gyuseong , Moon Jungsoon , Bronin Igor , Ivanova Christina , Cheng Joey T. , De Kock François , Graf Sylvie , Hřebíčková Martina , Halama Peter , Hong Ryan , Izdebski Paweł , Kulich Clara , Lorenzi-Cioldi Fabio , Penke Lars , Szarota Piotr , Tracy Jessica , Yang Yu , Funder David
Published: July 2019

The current project measures personality across cultures, for the first time using a forced-choice (or idiographic) assessment instrument - the California Adult Q-set (CAQ). Correlations among the average personality profiles across 13 countries (total N = 2,370) ranged from r = .69 to r = .98. The most similar averaged personality profiles were between USA/Canada; the least similar were South Korea/Russia/Poland and China/Russia. The Czech Republic had the most homogeneous personality descriptions and South Korea had the least. In further analyses, country differences in CAQ-derived Big Five scores were compared to results obtained from previous research using nomothetic Likert scales (i.e., the NEO; the BFI). The Big Five templates produced generally similar findings to previous research comparing the Big Five across countries using Likert-type methods.
Nuevo registro de sinantropía de Filistatoides insignis (Araneae: Filistatidae) en México y actualización del listado de arañas actuales de Chiapas
Authors: García-Villafuerte Miguel Angel , Brescovit Antonio Domingos
Published: July 2019

Con el descubrimiento de Filistatoides insignis (O. Pickard-Cambridge, 1896), un nuevo registro de araña sinantrópica para México, el presente estudio tiene como objetivo actualizar el listado de arañas actuales de Chiapas. Los especímenes fueron colectados en el Museo de Paleontología “Eliseo Palacios Aguilera”, ubicado en la ciudad de Tuxtla Gutiérrez. Con 533 especies de arañas actuales, Chiapas alberga el 22.2% de la biodiversidad total de arañas de México, ocupando el primer lugar en la riqueza de arañas para el país.
PERANAN KEPELATIHAN OLAHRAGA SEBAGAI PENDIDIK, PELATIH DAN PEMBINA OLAHRAGA DI SEKOLAH
Authors: Indrayana Boy
Published: July 2019

Pendidikan di sekolah sangat berperan dalam meletakkan dasar-dasar kemampuan, keterampilan, dan moral untuk mencapai peningkatan sumber daya manusia. Sekolah merupakan tempat yang potensial untuk mempersiapkan atlet dari usia dini. Pendidikan jasmani dapat menjadi alat pendidikan yang dapat menghasilkan atlet berpotensi dalam menunjuang prestasi olahraga nasional. Kepelatihan olahraga, sebagai tenaga professional, di samping menjadi tenaga pendidik dan pelaku kurikuler mampu menyelengggarakan program ekstrakulikuler sebagai peltaih dan Pembina olahraga di sekolah.Artikel ini membahas tentang kepelatihan olahraga di sekolah, aplikasi kepelatihan olahraga, kurikukulum pendidikan jasmani, pendidikan prestasi olahraga di sekolah, pengembangan calon atlet dari usia dini.Kata kunci: kepelatihan olahraga, pembinaan prestasi, sekolah.
TINGKAT PENGETAHUAN PELATIH BOLA VOLI TENTANG PROGRAM LATIHAN MENTAL DI KABUPATEN SLEMAN YOGYAKARTA
Authors: Syamsuryadin Syamsuryadin , Wahyuniati Ch. Fajar Sri
Published: July 2019

Penelitian ini bertujuan untuk mengidentifikasi tingkat pengetahuan pelatih bola voli tentang program latihan mental untuk atlet. Penelitian ini merupakan penelitian deskriptif dengan metode survey. Subyek penelitian ini adalah seluruh pelatih bola voli di Kabupaten Sleman yang sesuai kriteria sebanyak 16 orang. Hasil penelitian menunjukkan bahwa tingkat pengetahuan pelatih bola voli di Kabupaten Sleman tentang program latihan mental adalah sebagai berikut : berkategori “sangat kurang” sebesar 6,25%, kategori “kurang” sebesar 18,75%, kategori “cukup” sebesar 43,75%, kategori “baik” sebesar 18,75% dan kategori “sangat baik” sebesar 12,5 %. Nilai rata-rata yang dimiliki adalah 37,69 yang menunjukkan bahwa mayoritas pengetahuan pelatih bola voli tentang program latihan mental di Kabupaten Sleman berkategori sedang. Kata kunci : program latihan mental, pelatih bola voli, tingkat pengetahuan.
TATALAKSANA HENTI JANTUNG DI LAPANGAN PERMAINAN
Authors: Rizki Putra , Cahyani Nani
Published: July 2019

Cardiac arrest is the most common cause of sudden death in athletes on the field of play. There are reports of cardiac arrest in athletes 1: 4000 to 1: 8000.Cardiac and non-cardiac causes have been implicated as a causes of death in the field of play. Pre-Participation Evaluation (PPE) has been recommended for primary prevention of cardiac arrest in athletes due to cardiac problems. Prevention of sudden cardiac death on the field of the play should be done by immediate, precise and correct treatment. Immediate, precise and correct treatment can be provided if medical management is well performed before and during the event. Medical management in sudden cardiac arrest treatment on the field of play consists of early preparation, emergency action plan, preparing equipment, personnel, training, communication, transportation and final preparation. An ideal treatment includes elements of the chain of survival from sudden cardiac arrest.ABSTRAK Henti jantung adalah penyebab kematian mendadak terbanyak pada atlet di lapangan permainan. Terdapat laporan kejadian henti jantung pada atlet 1:4000 sampai 1:8000. Penyebab kematian akibat henti jantung di lapangan permainan bisa karena masalah jantung dan masalah selain jantung. Untuk pencegahan primer terjadinya henti jantung pada atlet di lapangan permainan yang disebabkan masalah jantung direkomendasikan melakukan Pre-Participation Evaluation (PPE). Untuk pencegahan terjadinya kematian akibat henti jantung di lapangan permainan harus dilakukan tatalaksana yang cepat, tepat dan benar. Tatalaksana yang cepat, tepat dan benar dapat diberikan jika manajemen medis dilakukan dengan baik sebelum dan saat event berlangsung. Manajemen medis dalam tatalaksana henti jantung di lapangan permainan terdiri dari persiapan awal, rencana kegawatdaruratan, mempersiapkan peralatan, personel, pelatihan, komunikasi, transportasi dan persiapan akhir. Tatalaksana di lapangan permainan yang ideal mencakup elemen rantai keselamatan pada henti jantung. Kata kunci: henti jantung, lapangan permainan, manajemen medis, penanganan SCA
KONTRIBUSI ANTARA KEKUATAN OTOT TUNGKAI DAN KEKUATAN OTOT PUNGGUNG TERHADAP KEMAMPUAN BANTINGAN PINGGANG OLAHRAGA GULAT ATLET PGSI PROVINSI BENGKULU
Authors: Martiani Martiani
Published: July 2019

Penelitian ini dilakukan untuk mengetahui kontribusi kekuatan otot tungkai dan kekuatan otot punggung terhadap kemampuan bantingan pinggang secara ilmiah. Adapun rumusan masalah dalam penelitian ini adalah berapa besar kontribusi kekuatan otot tungkai dan kekuatan otot punggung secara bersama-sama terhadap kemampuan bantingan pinggang dalam olahraga gulat? Penelitian ini dilakukan di sasana gulat PGSI Provinsi Bengkulu. Metode penelitian yang digunakan adalah metode korelasi product moment dan korelasi ganda, sampel penelitian berjumlah 30 atlet gulat PGSI Provinsi Bengkulu yang diambil dengan teknik total sampling. Adapun hasil data Rhitung = 0,91 > Rtabel = 0,361 maka Ho ditolak dan Ha diterima artinya terdapat hubungan yang berarti antara X1 dan X2 secara bersama-sama dengan Y. Kontribusi kekuatan otot lengan dan kekuatan otot punggung terhadap kemampuan bantingan pinggang yaitu K = r2 x 100% = 82,81%. Sehingga dapat disimpulkan bahwa adanya kontribusi positif antara kekuatan otot tungkai dan kekuatan otot punggung terhadap kemampuan bantingan pinggang sebesar 82,81%.AbstractThis study was conducted to determine the contribution of leg muscle strength and back muscle strength to the ability of the waist beating scientifically. The formulation of the problem in this research is how much contribution of leg muscle strength and back muscle strength together to the ability of waist beating in wrestling? This research was conducted in wrestling sasana PGSI of Bengkulu Province. The research method used is correlation method with product moment and double correlation, the samples are research 30 wrestling atlets of PGSI Bengkulu Province taken with total sampling technique. The result of data Rcount = 0.91> Rtable = 0.361 then Ho is rejected and Ha is accepted, it means that there is a meaningful relationship between X1 and X2 together with Y. Contribution of arm muscle strength and back muscle strength to the ability of waist beating that is K = r2 x 100% = 82.81%. So it can be concluded that there is a positive contribution between leg muscle strength and back muscle strength to the ability of waist beating by 82.81%.Keywords: leg muscle strength, back muscle strength, waist beating ability.
Factors Influencing the Utilization of Instructional Time in Technical Universities in Ghana: Implications for Adult Learning
Authors: Pajibo, PhD Edison Dehley
Published: July 2019

The primary intent of this study was to investigate factors that influence the utilization of instructional time in public technical universities in Ghana. The study was essentially a mixed method where descriptive survey was used. The target population was made up of classroom lecturers and heads of departments in Technical Universities in Ghana. Out of 10 public technical universities, 5 were selected. A sample size of 168 comprising 154 lecturers and 7 Vice Chancellors and 7 heads of departments was used. Sample selection method used was the multi-stage sample; cluster random sampling, simple random sampling, and purposive sampling techniques were employed. Questionnaire and interview schedules were used to collect data from participants. Percentages and frequencies were used to analyze all the responses from the questionnaire. Interview data were analyzed thematically. The findings revealed the technical universities lacked Teaching Learning Materials (TLMs) to facilitate teaching and learning and this posed problem for instructional time. It was concluded that the level of time utilization efficiency on the part of universities, management and lecturers was pertinent in achieving efficient time utilization. It was recommended that lecturers in technical universities particularly should establish instructional time management routines in their classrooms that are in line with improving teaching and learning.
O URSO E O DRAGÃO: ASPECTOS DA APROXIMAÇÃO POLÍTICA ENTRE RÚSSIA E CHINA NOS ANOS 2000
THE BEAR AND THE DRAGON: ASPECTS OF THE POLITICAL RAPPROCHEMENT BETWEEN RUSSIA AND CHINA IN THE YEARS 2000
Authors: Bezerra Valdir da Silva
Published: July 2019

Este artigo abordará alguns dos principais aspectos da aproximação política entre Rússia e China durante os anos 2000, sobretudo no que afeta aos interesses de Moscou nas relações internacionais. Para tal, objetiva-se analisar as relações entre os dois países em um plano mais amplo, incluindo-se, para além de suas tratativas comercias e políticas, a interação regional Rússia-China na Ásia Central e o significado de suas votações no Conselho de Segurança da ONU quanto à crise síria. Por fim, a partir da observação das principais provisões contidas em documentos oficiais dos eventos mais substantivos envolvendo os dois Estados, examinaremos a repercussão que uma China cada vez mais assertiva pode representar para a posição da Rússia no cenário internacional não somente em termos de benefícios, como também seus potenciais riscos.
EDUCAÇÃO EM DIREITOS HUMANOS: NECESSIDADE E DESAFIO PARA A EDUCAÇÃO BÁSICA
EDUCATION ON HUMAN RIGHTS: NEED AND CHALLENGE FOR BASIC EDUCATION
Authors: Nistler Regiane , Dalalba Jennifer , Souilljee Liege
Published: July 2019

A breve pesquisa tem como objeto a Educação em Direitos Humanos: desafio para a educação básica. O trabalho estuda na seção inaugural alguns marcos jurídicos dos Direitos Humanos que relatam a atuação de instituições internacionais, documentos também dessa natureza e evidenciam um processo de luta, bastante primário no que tange à cultura de efetivação e respeito a esses direitos. Em seguida, o estudo se debruça a analisar alguns fundamentos jurídicos que embasam a proposta pedagógica da Educação em Direitos Humanos que se propõe neste feito. O método de abordagem utilizado na elaboração desse trabalho foi o indutivo e o levantamento de dados foi através da técnica da pesquisa bibliográfica.
MIGRAÇÕES INFANTIS E O REGIME ONUSIANO DE PROTEÇÃO DOS DIREITOS HUMANOS
CHILD MIGRATION AND THE UNITED NATIONS RE-GIME FOR THE PROTECTION OF HUMAN RIGHTS
Authors: Zanatta Maria de Lourdes Alves Lima , Scherf Erick da Luz
Published: July 2019

A migração internacional faz parte do cotidiano de centenas de milhares de crianças ao redor do globo. Todavia, apesar das crianças muitas das vezes procurarem ativamente oportunidades de migração, desde a decisão de migrar até a trajetória e chegada na localidade de destino, elas podem se expor à diversos riscos. Desta maneira, esta investigação objetiva identificar a relação entre as migrações infantis e os regimes internacionais de proteção dos direitos humanos, mais especificamente o papel que o sistema global das Nações Unidas exerce na garantia do melhor interesse e dos direitos da criança migrante. O método que se adota é o dedutivo com o apoio da pesquisa bibliográfica e documental. As principais conclusões desta investigação foram que apesar da existência de princípios, normas, regras e procedimentos de tomada de decisão destinados à proteção dos direitos da criança migrante no âmbito do sistema global da ONU, estes mecanismos ainda necessitam de maior fortalecimento.
Regimes of Liability for Damages Caused by Abnormally Dangerous Activities
Authors: Rasnačs Lauris
Published: July 2019

The present paper examines certain aspects of liability for the damages caused by abnormally dangerous activities, mainly viewing them in the context of Latvian law. It addresses the questions which activities (and due to which particularities) shall be treated as abnormally dangerous, what kind of liability models could be applied for the compensation of damages caused by such activities, what is the role of insurance in this respect, to what extent strict liability or stricter forms of liability should be applied, as well as who shall be held liable for these damages.
PEMANFAATAN MEDIA PEMBELAJARAN DALAM UPAYA PENINGKATAN HASIL BELAJAR MAHASISWA
Authors: Aswar Cut
Published: July 2019

Existing interest that a person against an object is reflected in the behavior. Basically interest is motivated by a person's attention to a particular object of interest, such as attention, curiosity is high, and the need for decisive in selecting the objects to something. Thus, it can be confirmed that a person's interest depends on the attention, curiosity, needs and selection to choose his favorite activities. Interest that is an element in achieving success for someone. If someone is interested in a course, all the attention, curiosity, and the need for a course will be higher, so the higher the learning outcomes achieved on a course that followed. The existence turns impact student interest in learning that has a positive influence on the achievement of learning outcomes of a course. The higher the interest of learners in learning a subject, the higher the learning outcomes of a course he achieved. Conversely the lower the student's interest in learning a subject, then the lower the learning outcomes of a course that achieves.
PENGARUH MODEL PEMBELAJARAN TWO STAY TWO STRAY TERHADAP HASIL BELAJAR SISWA PADA MATERI REAKSI OKSIDASI DAN REDUKSI DI SMA BINA BANGSA ACEH BESAR
Authors: Badlisyah Teuku
Published: July 2019

In the learning process, most students have difficulties to understand the chemistry subject that delivered by the teacher. One thing that caused the difficulties of student learning was the minimum used of an appropriate learning model by the the teacher. This study was conducted to know the influence of Two Stay Two Stray learning model towards the improving of student learning result of Oxidation and Reduction Reaction Material, the student activity, and student response towards the study model of Two Stay Two Stray in SMA Bina Bangsa. The sample in this research was the students in class X of SMA Bina Bangsa. This research used the quantitative approach with a design research of Pre-Eksperimen. Data collection was done by multiple choice test, observation and student response questionnaire. The result showed that there was an increasing in student learning that taught by using learning model of Two Stay Two Stray at the test of normality with a significant level X2 count < X2 table or 1.467 < 11,1 states that the test has a normal distribution, whereas the t test with significance level of Tcount > Ttable or 8.251 > 2.13 that states there was an influence towards the students study research by using the Two Stay Two Stray model, while by n-Gain test the average students reaches the high criteria. The observation result of student activity has increased from 79.14% at the 1st meeting to become 88.33% at the 2nd meeting, the students also have a positive response towards the application of Two Stay Two Stray model study on Oxidation and Reduction Reaction material, with the student response percentage of â€œYesâ€ was 84% which means the students were interested with the Two Stay Two Stray model study.
FUNGSI TIROID DAN KOGNITIF SISWA SEKOLAH DASAR DENGAN STUNTING DI DAERAH REPLETE DAN NON REPLETE GAKI
Authors: Riyanto Slamet , Yunitawati Diah , Nur'aini Nafisah
Published: July 2019

Latar Belakang. Pertumbuhan anak baru masuk sekolah dasar (6-8 tahun) di daerah endemik GAKI cenderung lebih buruk dibanding anak dengan usia sama di daerah non-endemik. Kekurangan asupan iodium dapat berdampak pada gangguan perkembangan fungsi kognitif anak. Kondisi stunting juga berdampak pada gangguan fungsi kognitif anak Tujuan. Penelitian ini bertujuan untuk mengetahui perbedaan fungsi tiroid dan kognitif siswa sekolah dasar yang mengalami stunting di daerah replete dan non replete GAKI. Metode. Rancangan penelitian ini adalah cross sectional. Lokasi penelitian di Kabupaten Magelang yaitu Kecamatan Ngablak sebagai daerah replete GAKI dan Kota Mungkid sebagai daerah non replete. Jumlah minimal partisipan 28 siswa stunting dan 28 siswa dengan status gizi normal di masing-masing daerah. Hasil. Seluruh kelompok responden memiliki asupan iodium berlebih (median UIE ≥200 µg/L). Tidak terdapat perbedaan fungsi tiroid (TSH dan fT4) pada keempat kelompok responden (p>0,05). Terdapat perbedaan IQ dikeempat kelompok, dimana kelompok responden dengan tinggi badan normal di daerah non replete memiliki IQ paling tinggi (104±13,1). Kesimpulan. Fungsi tiroid siswa dalam kondisi normal. IQ siswa sekolah dasar dengan tinggi badan normal di daerah non replete GAKI lebih tinggi dibanding pada siswa stunting di daerah yang sama maupun siswa normal dan stunting di daerah replete GAKI.
To Critique or not to Critique? That is (perhaps not) the Question…
Authors: Appel Hannah
Published: July 2019

Comment on Salverda:To Critique or not to Critique? That is (perhaps not) the Question…
Mediação em museus e em exposições: espaços de aprendizagem sobre arte e seu sistema
Authors: Grinspum Denise
Published: July 2019

O texto apresenta uma reflexão sobre os contextos de aprendizagem em museus de arte e discute os recursos didáticos apropriados para o desenvolvimento da compreensão estética. Propõe-se também a compreensão do sistema da arte para a inteligibilidade da produção artística contemporânea, sublinhando as dificuldades na definição de parâmetros para a sua aprendizagem.
Padre Matria (Meu inimigo, o ícone)
Authors: Camnitzer Luis
Published: July 2019

O artigo aborda, pela perspectiva dos estudos decoloniais, a transformação, pela arte, do ícone linguístico “madre patria” – que se refere à Espanha em relação aos países colonizados pelos espanhóis. Considerando que a linguagem sempre serve ao colonizador, o texto mostra que esse termo dissimula a situação política de submissão do colonizado, ao ressaltar um aspecto positivo, qual seja, um lugar acolhedor para onde sempre se pode retornar. Em “Padre Matria”, num jogo de palavras, o ícone “madre patria” é desconstruído, desnudando a metáfora original e eliminando a hipocrisia da benevolência do colonizador. O texto reflete sobre a transformação de um ícone em unidade cultural: o que faz um objeto ser arte? Afirma que o consumo acrítico de ícones e memes passivos é uma porta aberta aos processos de colonização. Ao contrário, como em “Padre Matria”, estratégias de sincretismo, mudanças de contextos, atribuição de novos significados às coisas e a interatividade com memes contemporâneos são alguns dos passos que fazem parte da história da resistência anticolonial. E isso deve estar no ensino da arte nas escolas.
Políticas públicas e estratégias de fomento para as artes indígenas: o modelo australiano
Authors: Goldstein Ilana Seltzer
Published: July 2019

O presente texto aborda as estratégias de fomento às artes indígenas desenvolvidas na Austrália, que incluem premiações, um código de conduta comercial, apoio do governo federal às cooperativas indígenas, entre outras medidas. O caso australiano é único no mundo, em termos do grau de institucionalização, visibilidade e valorização que os artistas aborígenes atingiram. Nesse sentido, oferece um contraste interessante para se refletir sobre o contexto latino-americano. Também suscita questões de cunho ético e político, em se tratando de um país com passado colonial tão violento.
Aproximación para establecer y evaluar la relevancia clínica de las interacciones medicamentosas en el tratamiento de pacientes infectados con virus de hepatitis C, revisión estructurada (actualización 2015 – 2017)
Authors: Pino Marín Daniel Esteban , Amariles Pedro , Peláez Alvárez Jaime Alberto , Alvárez Osorio Gloria Priscilla , González Ceballos Juliana
Published: July 2019

Objetivo: establecer y evaluar la relevancia clínica de las interacciones medicamentosas en el tratamiento de pacientes con hepatitis C.

Método: se realizó una búsqueda en PubMed/MedLine de artículos publicados en inglés y en español, desde el 1 de enero de 2015 hasta el 30 de marzo de 2017, utilizando los términos Mesh: Hepatitis C AND drug interactions OR herb-drug interactions OR food-drug interactions, de estudios realizados en humanos. La relevancia clínica de las interacciones medicamentosas se estableció y evaluó con base en la probabilidad de ocurrencia y la gravedad de la interacción.

Resultados: se identificaron 184 artículos, de los cuales 92 se seleccionaron por el título y resumen para revisión completa, a 2 de ellos no fue posible acceder al texto completo. De estos, 57 aportaban interacciones, lo que permitió identificar 155 parejas de interacciones medicamentosas, de las cuales 154 (99,4 %) fueron farmacocinéticas y 1 (0,6 %) farmacodinámica. Por su parte, de las 155 parejas, 34 (21,9 %) se valoraron de nivel 1; 73 (47,1 %) de nivel 2; 48 (31,0 %) de nivel 3; y 0 (0,0 %) de nivel 4. Además, se identificaron 29 parejas agrupadas como interacciones con evidencia de ausencia de relevancia clínica.

Conclusiones: más de 99 % de las interacciones medicamentosas de relevancia clínica son farmacocinéticas, asociadas con cambios en el metabolismo y el transporte de fármacos; el simeprevir y la terapia 3D (Paritaprevir/Ritonavir+ Ombitasvir+Dasabuvir) fueron los medicamentos con mayor número de interacciones.
Colangiopancreatografía retrograda endoscópica (CPRE) transgástrica asistida por laparoscopia en un paciente con Bypass gástrico en-Y-de Roux. Reporte de un caso y revisión de la literatura
Authors: Peñaloza Ramírez Arecio , Contento Anaya Fabio Andrés , Ramírez Rueda Juan C , Córdoba Chamorro Adriana , Aponte Ordoñez Pedro
Published: July 2019

La obesidad es un problema de salud pública. La cirugía bariátrica juega un papel importante en el manejo de estos pacientes. Con la llegada de estas técnicas quirúrgicas, los procedimientos endoscópicos digestivos y en especial la colangiopancreatografía retrógrada endoscópica (CPRE) se convierten en un desafío constante. Se describe un caso de CPRE transgástrica asistida por laparoscopia para el manejo de cálculos de la vía biliar principal en un paciente con antecedente de derivación gástrica en Y de Roux (BPGYR).
Some quantitative genetic traits in Vietnamese indigenous Noi chicken from 0 to 28 days old
Authors: Khoa Do , Tuoi Nguyen , Nguyen Nguyen , Thuy Nguyen , Okamoto Shin , Kawabe Kataro , Shimogigri Takeshi
Published: July 2019

The aim of this study is to characterize some quantitative traits of Noi
chicken, one of the Vietnamese famous native breeds for meat quality and
fighting, at the stage of 0-28 days old. Therefore, 742 chicks were used to
measure, record, analyze and evaluate on these traits. As results, there was
significant difference in observation traits among stages of age (P=0.000).
Interesting, the wings (+64.88%) and keel lengths (+58.83%) rapidly
developed within the first week of life, followed by the most of other
dimensions, especially breast diameter (+31.85%), thigh diameter (+71.17%)
in the second week of age. An increase in the size of the measurements was
due to development of the skeleton at observing time points along the
experiment. However, there was strong development of muscle tissue in the
second week of life as rate of the breast and thigh diameter was greatest.
Noi chicks consumed amount of feed of 16.54 g/bird/day and gained a weight
of 6.98 g/bird/day. Thus, their feed conversion ratio was 2.37 at the stage
of 0-28 days old. Perhaps a direct positive relationship between observed
traits and age were randomly established according biological
characteristics of animal. This work provided initial benchmarks of Noi
chicks for further studies.
Retrospective analysis of the frequency and contributory causes of ascites syndrome in broilers in South Banat
Authors: Gavrilovic Pavle , Zivulj Aleksandar , Todorovic Igor
Published: July 2019

Ascites syndrome is a multi-factorial, noncontagious disease of broilers.
Chickens selected for rapid growth have a high basal metabolism and
consequently increased demands for oxygen. Poor environmental conditions and
other unfavourable factors which reduce the amount of available oxygen cause
hypoxia, pulmonary hypertension, right ventricular dilation and right heart
failure, which results in generalized passive hyperaemia of organs and
ascites as the most striking gross pathology manifestation. The aim of the
study was to investigate, retrospectively, the frequency of the disease in a
selected district with widespread poultry production and to identify main
factors that contribute to the outbreak of the disease. In the period from
2011 to 2017 ascites syndrome was diagnosed by post mortem examination of
chickens in 12 out of 91 flocks with health disorders, examined in the
Veterinary Specialized Institute "Pancevo". Based on anamnesis, signs of
disease and pathomorphological findings, poor environmental conditions and
inadequate feed were identified as main contributory factors. In the
majority of cases ascites syndrome occurred in small flocks, raised in
unsuitable environmental conditions.
Livestock in rural piedmont regions of Algeria
Authors: Bengouga Khalila , LahmadiSalwa L , Zeguerou Reguia , Maaoui Moufida , Halis Youcef
Published: July 2019

A livestock survey conducted during 2013/2015 as part of a CRSTRA project in
4 villages situated at North east Biskra and south Batna in Algeria. These
regions are located at elevation ranging around 250-831m asl, experiencing
arid and semi-arid Mediterranean climate. Respondents of 86 families
demonstrated that livestock is an integral part of the region?s mixed
farming systems. Low livestock numbers per most households at present
reflect the self-consumption breeding mode adapted in these regions.
Currently, farmers focus on four main livestock types; goat, sheep, chicken
and bee keeping in two regions, it is the case of Beni Souik and Branis ,
while Maafa includes beyond these types, turkey and pigeon whereas Ain
Zaatout includes duck and swine beside the previous livestock types. In the
same context; goat ranked first in the four regions, goat and sheep secondly
then goat and poultry with goat combined to sheep and poultry in third
place. Thus; most families use a combination of grazing, agriculture
sub-products and industrial products for the nutrition of their livestock.
Families keep livestock as source of milk, butter, wool or hair, leather and
other products that are strongly used as nutritional, weaving supply or
stocking covering resources for the family members or friends and in some
cases for sell to seekers of animal products of indigenous territory
origins. Most families use these products for family and friend consumption
while a minority sell some of them on local markets.
Application of lexical bundles from biotechnical research articles in ESP teaching
Authors: Lazic Katarina
Published: July 2019

This paper presents the possibility of applying a list of lexical bundles
that have been singled out as the most common or typical in the texts of
native English speakers. These bundles belong to biotechnical research
articles and this study reveals how lists of pedagogically useful lexical
bundles could be transferred to teaching materials intended for non-native
speakers who aim to master their writing skills for the purpose of writing
research papers in English in the field of biotechnology. Lexical bundles
occurring in all subcorpora of biotechnical articles, i.e. the subcorpora of
forestry, landscape architecture, ecological engineering and wood processing
point to those groups of lexical bundles whose proper use should first be
adopted by the authors of biotechnical articles, while the results of their
classification and further analyses provide materials for exercises which
aim to teach their use. In this way, our research responds to the invitation
of the study Chen and Baker (2010), which urges pedagogues and publishers to
use more results of automated corpus research in teaching.
Land cover monitoring as part of a survey on wetland ecosystem conservation in the Negovan village area using remote sensing tools
Authors: Radeva Kameliya , Velizarova Emiliya , Dancheva Adlin
Published: July 2019

The main purpose of the present survey is to apply remote sensing data to the
investigation of different components of a wetland ecosystem, situated in
the area of the village of Negovan (Sofia region), such as soil, vegetation
and water, and their variation for certain temporal intervals including the
vegetation period. This survey represents the process of interim ecological
monitoring (IEM) implementation on the studied ecosystem. Data for the
current condition of different ecosystem components - soil, vegetation and
water components, and their variations within the selected time period of 5
years (2014-2018) have been obtained. Specific relations among wetland
actual components conditions such as soil wetness and vegetation vs climate
factors within the respective temporal intervals of wetland monitoring
process have been established. Aerospace data with different temporal, space
and spectral resolution, satellite data from Sentinel 2, MSI and aerophoto
with a very high resolution have been used. The results for ?Brightness?,
?Greenness? and ?Wetness? components obtained on the basis of
orthogonalization of satellite data from Sentinel 2 have been introduced.
The results reflect the value of Soil Adjusted Vegetation Index (SAVI),
Modified Soil Adjusted Vegetation Index (MSAVI 2), Normalized Difference
Greenness Index (NDGI) and Normalized Difference Water Index (NDWI), which
are of great importance for the relationship between soil health indexes and
ecosystem sustainability. Thematic maps are generated based on the results
obtained by surveying land cover components. Data received for the current
condition of Negovan wetland ecosystem and established variations of
different parameters, including soil component could be used while assessing
wetland ecosystem services.
Environmental and economic effects of investments in sustainable land management in the basin of Sutilovac stream
Authors: Roncevic Vukasin , Zlatic Miodrag , Todosijevic Mirjana
Published: July 2019

This paper presents the results of an erosion processes research on the
territory of the morphological unit of Sutilovacki stream, the prevention
measures of same processes, as well as the justification of socio-economic
investments and a sensitivity analysis of the economic efficiency
parameters. The research includes a period from 2017-2032 year, whereby the
evaluation methods of professor Gavrilovic are applied in erosion process
intensity assessment, on the whole research area, and universal soil loss
equation - USLE, on the agricultural land area. Different rates of soil
erosion vulnerability are established on the whole research area by applying
these methods. Present erosion processes are prevented by the predicted
model of future production from the aspect of soil resource protection in
the area of the city of Belgrade, by professor Zlatic (1994). Erosion soil
losses are significantly diminished and reduced under a tolerable limit,
along with the accomplishment of socio-economic justification of investment,
examined by the dynamic methods of internal rate of yield, term for the
repayment of invested funds, cost-benefit ratio, and net present value. In
addition, an analysis of internal rate of yield sensitivity and term for
repayment of invested funds are executed. The obtained data indicate
justification of the investment.
Challenges of transnationalism among the second generation of Serbian migrants in Switzerland
Authors: Todorovic Milica
Published: July 2019

This paper presents the results of a survey conducted among members of the
second generation of Serbian migrants born in Switzerland. Thanks to the
data obtained through the application of qualitative research, there are
presented activities of the respondents in the transnational area. Their
engagement on the route between Serbia and Switzerland is reflected in four
areas of transnationalism: direct/indirect contacts, transnational
engagement in the receiving state, remittances and visits to the country of
origin and return plans. The results indicate that children of migrants who
come from a family whose members are active in a transnational space, in
most cases, adopt the same norms of behavior and it plays a crucial role in
the process of identity formation. However, their transnational behavior on
the relationship between the two states has different form, and the
transnational activities examined do not condition each other.
A Fuzzy MCDM Approach to Determine the Most Influential Logistic Factors
Authors: ŞENOL Mehmet Burak , ADEM Aylin , DAĞDEVİREN Metin
Published: July 2019

The art of managing materials; logistics play a
crucial role in efficiency and productivity of companies. It is very
significant to determine most influential logistic factors since logistic costs
account for 30% of total company costs. The factors affecting success of
logistic enterprises such as cost, speed, reliability, customer satisfaction,
distribution channel, company image, environmental friendliness and
technological innovations are investigated and ranked in this study. Three
different approaches based on Pythagorean Fuzzy sets, triangular fuzzy numbers
and Analytic Hierarchy Process is offered for ranking these factors. Although
it has been introduced to literature recently, the pythagorean fuzzy sets are
widely employed in calculating uncertainty. The three most influential logistic
factors are revealed as cost, speed and reliability, respectively by employing
AHP, Fuzzy AHP and Pythagorean Fuzzy AHP, however factor weights are different.
We think that the differences with in the AHP, F-AHP and PF-AHP results may
stem from expressing evaluations in exact values, linguistic terms or in some
cases it may be related to fulfilling the condition of membership and
non-membership. Furthermore, top 10 logistic firms in Turkey are scored and
ranked to these factors. Logistics, Pythagorean fuzzy sets, AHP, Fuzzy AHP,
MCDM.
An Evaluation of Malaria Control Practices by Caregivers of Under-5 Children in Calabar South Local Government Area of Cross River State, Nigeria
Authors: Andrew Agbenin , Akpan Edem A.
Published: July 2019

Background: Despite many years of research and concerted efforts at control of malaria, the achievement of a malaria free world remains a dream. The prevalence of the disease continues to increase in many parts of the world especially among under-5 children and pregnant women. However, in Nigeria, the scale up of malaria control strategies has produced recognizable public health impact in several communities and this has led to the development of new tools and strategies, including integrated approach to control, aimed at further consolidating malaria control goals. Objectives: To evaluate malaria control practices by Caregivers of under-five children in Calabar South LGA, Cross River State, Nigeria. Methods: A cross sectional study involving the administration of questionnaires to 440 Caregivers of under-five children selected through a multi-stage sampling and simple random sampling techniques. The administration of the questionnaires to the respondents was used to evaluate malaria control practices by Caregivers of under-5 children in Calabar South LGA since the launch of the Roll back Malaria (RBM) Program in Nigeria in 1998. Results: The sociodemographic characteristics of respondents are as follows: 35.3% of respondents fell within the age brackets of 26-31 years, 85% were married, 56.3% had, at least, secondary school education, 35.8% were traders, 98.5% were Christians, 40.8% were medium income earners, 56.3% had 3-5 persons per household. Evaluation of Caregivers in the LGA on knowledge of malaria control practices, show they had good knowledge on strategies to control malaria but many of them did not practice them in their homes. The very few that were involved in the practice of malaria control activities rely on vertical approaches to control instead of integrated malaria control efforts as advocated during the launch of the RBM program in Nigeria in 1998. Conclusions: The state Ministry of Health, Calabar, Cross River State, Nigeria, through the Department of Public Health, needs to invest more on education, communication and information dissemination strategies to reach Caregivers of under-5 children to adopt integrated approach to malaria control instead of using isolated vertical approach if they are to achieve the malaria control targets set by RBM and MDGs for under-5 children in Nigeria in general and Calabar South LGA in particular.