bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH WORK LIFE BALANCE DAN LINGKUNGAN KERJA TERHADAP KEPUASAN KERJA KARYAWAN GENERASI MILENIAL DI PT TELKOM INDONESIA PADA UNIT DIGITAL OPERATION AND ASSURANCE DENGAN PENGEMBANGAN KARIR DALAM PERSPEKTIF ILMU ISLAM
Authors: Dwi Hartono Bambang , Sarji Sarji , Windiana Sari Anggita
Published: September 2024

Generasi milenial saat ini dominan dalam tenaga kerja PT Telkom Indonesia, termasuk unit Digital Operation and Assurance. Mereka mencari keseimbangan antara pekerjaan dan kehidupan pribadi serta lingkungan kerja yang mendukung untuk meningkatkan kepuasan kerja. Penelitian ini bertujuan untuk memahami peran work life balance, lingkungan kerja, dan pengembangan karir dalam meningkatkan kepuasan kerja karyawan milenial di unit tersebut, dengan perspektif nilai Islam yang menekankan keseimbangan, keadilan, dan tanggung jawab dalam kehidupan kerja. Metode survei dengan kuesioner digunakan untuk mengumpulkan data dari karyawan milenial. Hasil analisis regresi menunjukkan bahwa work life balance dan lingkungan kerja berkontribusi signifikan terhadap kepuasan kerja, sementara pengembangan karir memainkan peran intervening yang penting. Implikasi manajerial dari penelitian ini adalah perlunya PT Telkom Indonesia untuk meningkatkan kebijakan yang mendukung work life balance, menciptakan lingkungan kerja yang kondusif, dan menyediakan program pengembangan karir yang berkelanjutan untuk memastikan kepuasan kerja yang optimal bagi karyawan milenial.
Special Issue on WALCOM 2023: Guest Editors' Foreword
Authors: Lin Chun-Cheng , Lin Bertrand M.-T. , Liotta Giuseppe
Published: September 2024

Special Issue on WALCOM 2023: Guest Editors' Foreword
Graph Burning in Community-based Networks
Authors: Cordasco Gennaro , Gargano Luisa , Rescigno Adele A.
Published: September 2024

Graph burning is a deterministic, discrete-time process that can be used to model how influence or contagion spreads in a graph. In the graph burning process, each node starts as dormant, and becomes informed/burned over time; when a node is burned, it remains burned until the end of the process. In each round, one can burn a new node (source of fire) in the network. Once a node is burned in round $t$, in round $t+1$, each of its dormant neighbors becomes burned. The process ends when all nodes are burned; the goal is to minimize the number of rounds.We study a variation of graph burning in order to model spreading processes in community-based networks. With respect to a specific piece of information, a community is {\em satisfied} when this information reaches at least a prescribed number of its members. Specifically, we consider the problem of identifying a minimum length sequence of nodes that, according to a graph burning process, allows to satisfy all the communities of the network. We investigate this NP-hard problem from an approximation point of view, showing both a lower bound and a matching upper bound. We also investigate the case when the number of communities is constant and show how to solve the problem with a constant approximation factor.Moreover, we consider the problem of maximizing the number of satisfied groups, given a budget $k$ on the number of rounds.
Some Algorithmic Results for Eternal Vertex Cover Problem in Graphs
Authors: Paul Kaustav , Pandey Arti
Published: September 2024

The eternal vertex cover problem is a variant of the vertex cover problem. It is a two-player (attacker and defender) game in which, given a graph $G=(V,E)$, the defender needs to allocate guards at some vertices so that the allocated vertices form a vertex cover. The attacker can attack one edge at a time, and the defender needs to move the guards along the edges such that at least one guard moves through the attacked edge and the new configuration still remains a vertex cover. The attacker wins if no such move exists for the defender. The defender wins if there exists a strategy to defend the graph against infinite sequence of attacks. The minimum number of guards with which the defender can form a winning strategy is called the eternal vertex cover number of $G$, and is denoted by $evc(G)$. Given a graph $G$, the problem of finding the eternal vertex cover number is NP-hard for general graphs and remains NP-hard even for bipartite graphs. We have given a polynomial time algorithm to find the Eternal vertex cover number in chain graphs and $P_4$-sparse graphs. We have also given a linear-time algorithm to find the eternal vertex cover number for split graphs, an important subclass of chordal graphs.
Le visage de l’hébreu au grec : au sujet de l’emploi de prosôpon dans le Pentateuque grec
Authors: Maurais Jean
Published: September 2024

Le terme hébreu pānîm est notamment employé pour dénoter le visage, mais aussi pour former des prépositions complexes (« en présence de ») ou des tournures idiomatiques (« lever le visage de »). Ces expressions ont occasionné de nombreux défis aux traducteurs de la Septante. L’examen d’une variété d’exemples tirés du Pentateuque grec révèle un certain nombre d’innovations linguistiques impliquant le terme prosôpon. De même, les endroits où l’équivalence avec prosôpon est parfois évitée, soit pour des considérations linguistiques ou idéologiques, sont aussi d’intérêt. Lorsqu’il est question de Dieu, certaines tournures de l’hébreu semblent avoir été consciemment reformulées. Les traducteurs révèlent ainsi leur créativité pour résoudre des noeuds théologiques pour leurs lecteurs.
Cartographie écopoétique des visages du Cantique des cantiques comme agencements plus qu’humains
Authors: Doane Sébastien
Published: September 2024

Contrairement aux interprétations anthropocentriques du Cantique des cantiques qui lisent ses références non humaines comme des métaphores descriptives d’un couple humain, cet article propose de lire cet agencement poétique à partir des concepts de « rhizome » et de « visagéité » théorisés par les philosophes Gilles Deleuze et Félix Guattari. Ce paradigme de lecture permet de mieux valoriser l’hybridité interespèce propre aux visages des amants. La lecture rhizomique du Ct permet de décloisonner les frontières des identités humaines, animales, végétales, minérales et architecturales. La fécondité de cette approche herméneutique est illustrée avec le motif particulier du « pommier » (Ct 2,3-6 ; 7,7-9 ; 8,5). Ultimement, cette expérience de lecture montre les limites du cloisonnement anthropocentrique de « la nature » et plaide pour une meilleure prise en compte de la multiplicité et de l’interconnectivité de la vie par la poésie biblique.
Chercher Dieu dans ces villes aux mille visages
Authors: Bergeron Patrice
Published: September 2024

« Nous avons besoin de reconnaître la ville à partir d’un regard contemplatif, c’est-à-dire un regard de foi qui découvre ce Dieu qui habite dans ses maisons, dans ses rues, sur ses places » (François, Exhortation apostolique Evangelii Gaudium, 24 novembre 2013, no 71). Il y a une bonne part d’audace dans cette interpellation, car la « présence de Dieu » en ville ne saute pas nécessairement aux yeux, plus encore lorsqu’on y cherche le Dieu Sauveur. Néanmoins, que voit-on de Dieu dans ces villes aux mille visages, quand on ose le chercher ? Qu’est-ce qui caractérise une telle démarche de discernement spirituel ? Autrement dit, que voit-on et comment voit-on ? Telles sont les questions que cet article explore théologiquement à partir d’une série de témoignages écrits par des chrétiennes et des chrétiens formés aux « Exercices spirituels ignatiens » qui, au coeur de leur ville de résidence sur différents continents, ont été invités à contempler en marchant. L’analyse de ces témoignages permet non seulement d’éclairer le croire chrétien en acte et le travail du regard interprétant au coeur de l’espace urbain, elle montre aussi comment un tel regard parvient à discerner des traces de la grâce au coeur de l’ambivalence urbaine.
La Révolution tranquille rencontre le surréalisme : Acte 2 – Déclôturer le droit des biens québécois
Authors: Gidrol-Mistral Gaële , Popovici Alexandra
Published: September 2024

Le 13 avril 2019, « un (nouveau) Code civil » est né. Le législateur belge a en effet décidé de réformer son droit civil en profondeur et, depuis le 1er novembre 2020, le Code civil du 21 mars 1804 (le Code Napoléon) est devenu, pour les Belges, l’« ancien Code civil ». À partir d’une lecture du livre 3 « Les Biens » du Code civil belge (acte 1), les autrices offrent une étude comparative qui propose une analyse textuelle et conceptuelle du Livre 4 - « Des biens » du Code civil du Québec afin de revisiter les théories qui soutiennent son droit des biens.
Les usages récurrents (et oubliés) des peines radicales en droit criminel : un exemple canadien sur des peines dites à rabais
Authors: Audesse Alexandre , Cauchie Jean-François , Sauvageau Jean
Published: September 2024

À travers le développement de la notion de peine radicale, le présent article propose une analyse réflexive sur certains états du droit criminel canadien. Fondamentalement heuristique, la notion de peine radicale sera utilisée pour explorer la manière dont la sphère politique et les cours de justice sont bien souvent marquées par un attachement aveugle à des réponses pénales qui bafouent les droits fondamentaux. Pour ce faire, les auteurs offrent une série d’analyses sociologiques sur les décisions relatives aux meurtres multiples qui ont suivi le projet de loi C-48, loi qui recommandait l’imposition de périodes d’incarcération minimale consécutives au nom de la vie de chaque victime. Plus précisément, après avoir montré l’ouverture des tribunaux de première instance à l’idée d’imposer des sanctions radicalement indifférentes à la vie sociale et biologique des condamnés, les auteurs exposent que l’abolition de la loi C-48 par la Cour suprême du Canada – dans l’arrêt R. c. Bissonnette – ne fait pas du droit canadien un droit respectueux de la dignité humaine et des autres préceptes enchâssés dans la Charte canadienne des droits et libertés.
La légalité des questionnaires médicaux de préembauche : pour une approche cohérente et unifiée
Authors: Tremblay Potvin Charles , Quilès Simon
Published: September 2024

En 1982, le législateur québécois a formellement reconnu le caractère subreptice de la discrimination dans l’embauche en modifiant la Charte des droits et libertés de la personne pour y inclure l’article 18.1, lequel interdit de requérir des renseignements relatifs aux motifs de discrimination énumérés à l’article 10 dans le contexte d’un processus d’embauche. Cependant, force est de constater que la jurisprudence relative à l’article 18.1 n’est pas des plus limpides. Dans le présent texte, en traçant préalablement le portrait du droit applicable en matière de collecte d’informations à l’embauche, les auteurs visent à proposer une approche cohérente et unifiée pour appréhender la question de la légalité des questionnaires et des examens à caractère médical en pareil contexte. Par « cohérente », ils entendent une grille d’analyse dépourvue de contradictions ; par « unifiée », ils avancent que l’approche devrait être la même, quel que soit le tribunal appelé à statuer sur cette question, ce qui permettrait d’éviter ainsi le développement de courants jurisprudentiels incompatibles. L’approche suggérée se trouve dès lors modulée en fonction du contexte litigieux dans lequel le questionnaire médical est mis en preuve plutôt que de l’instance juridictionnelle appelée à trancher le litige.
Conservación de tejidos y células de lince ibérico (Lynx pardinus), lince boreal (L. lynx) y lince rojo (L. rufus) para el establecimiento de un banco de recursos genéticos.
Authors: Crespo Cristina , Gañán Natalia , Pulido Laura , Osuna Gema , Gomendio Montserrat , Roldán Eduardo R.S.
Published: September 2024

Many species face considerable difficulties in maintaining viable populations under natural conditions. This is the case of the Iberian lynx, the most endangered felid in the world. Despite substantial conservation efforts in its natural habitat, the population size is decreasing. Thus, ex-situ conservation strategies must be implemented, aimed at preserving the maximum genetic variation through conserving biomaterials in a genetic resource bank, and the future use of these materials by means of reproductive biotechnologies. We obtained tissue explants from biopsies and necropsies, and transported them to the laboratory under thermal isolation. Part of the tissue was cryopreserved and the rest was incubated to collect and cryopreserve fibroblasts. Tissue samples and fibroblasts are currently cryopreserved in liquid nitrogen. We used skin samples from bobcats and Eurasian lynxes as models. Tissue and cells from 2 bobcats were cryopreserved and viable cells were recovered after being preserved for 9 months. Skin samples were biopsied from 7 Eurasian lynxes and cells were preserved from 57% of the animals; the main problem encountered was contamination during sample collection and transport. Biomaterials from 13 Iberian lynxes were obtained (7 biopsies, 6 necropsies). Cells were obtained and cryopreserved from 86% of biopsies. Regarding necropsy tissue, samples were cryopreserved for all individuals (100%), and cells from 67% of them. The successful cryopreservation of tissue and cells from live and dead lynxes highlights the advantages of rescuing these genotypes and the potential use of these biomaterials.
Descripción del crecimiento de la primera cuerna en ciervo ibérico (Cervus elaphus hispanicus).
Authors: Gaspar-López Enrique , García Andrés José , Landete-Castillejos Tomás , Carrión Déborah , Gómez José Ángel , Estévez José Antonio , Gallego Laureano
Published: September 2024

Se estudió el crecimiento de la primera cuerna en 25 ciervos ibéricos de la Granja Experimental de la UCLM en Albacete mediante la determinación quincenal de su peso corporal y la longitud de su cuerna. Los animales nacieron del 25 de abril al 6 de septiembre de 2002, presentando un peso de 8,7±0,2 (6,2-11,0) kg. El pedículo apareció con 35,4±0,4 (32-39) semanas de edad, con fecha y peso medios el 23 de marzo y 61,9±1,2 (52,0-72,0) kg. El crecimiento de la cuerna comenzó con edad y peso medios de 38,5±0,5 (34-44) semanas y 68,3±1,1 (57,0-78,8) kg, durando 15,8±0,4 (12-20) semanas. Este proceso terminó el 3 de agosto, con una edad y peso medios de 54,3±0,6 (50-62) semanas y 93,0±2,1 (74,2-111,4) kg. El descorreo duró 6,1±0,5 (3-14) semanas, concluyendo el 10 de septiembre de 2003, cuando los animales tenían 60,6±1,0 (55-70) semanas de edad y 99,0±1,6 (82,2-123,1) kg de peso. El desarrollo de la primera cuerna se produjo con una velocidad de crecimiento que se incrementó hasta la quincena 7, en la que se registró el mayor crecimiento quincenal de la primera cuerna. A partir de este momento, la velocidad de crecimiento de la primera cuerna decreció, siendo la quincena 12 la última en la que registró crecimiento de la primera cuerna. La primera cuerna se desarrolló con una velocidad de crecimiento que se incrementó en la primera mitad de su desarrollo, alcanzando su mayor valor en la quincena 7. A partir de ese punto su valor medio decreció, hasta ser nulo en la quincena 12. La longitud de la cuerna mostró unas 4 primeras y últimas dos quincenas de lento crecimiento y otras 5 (quincenas 4-9) de rápido crecimiento. La longitud media obtenida en la quincena 11, de 39,6±1,2 (29,0-56,0) cm no sufrió modificaciones en quincenas posteriores.
A comunidade de mamiferos não voadores da paisagem protegida da Serra de Montejunto (Centro de Portugal): distribuiçao e situaçao regional.
Authors: Loureiro Filipa , Sousa Mónica , Basto Mafalda , Pedroso Nuno , Rosario João , Sales-Luis Teresa , Chambel Isabel , Rosalino Luis Miguel
Published: September 2024

Na sequência de um incêndio que afectou a Paisagem Protegida da Serra de Montejunto (PPSM) no Verão de 2003, a Câmara Municipal do Cadaval promoveu a realização de um estudo para adquirir informação base para a elaboração de um plano de conservação direccionado aos vertebrados terrestres. O trabalho aqui apresentado, visou inventariar as espécies de mamíferos não voadores presentes na PPSM, determinar a sua distribuição, definir “hotspots” de biodiversidade, áreas prioritárias e identificar problemas de conservação. A área da PPSM situa-se no Centro Litoral de Portugal a cerca de 50 km a Norte de Lisboa e ocupa 5000 ha. A metodologia utilizada consistiu de uma combinação de armadilhagem para micromamíferos, transectos pedestres, consulta de especialistas e análise de regurgitações e dejectos. Por cada quadrícula de 1x1 km realizou-se um transecto pedestre diurno de 1,5 km de extensão e cujo percurso reflectiu a frequência relativa dos usos do solo presentes na quadrícula. Confirmou-se a presença de 17 espécies de mamíferos, distribuídos homogeneamente em toda a PPSM, não tendo sido possível detectar nenhum padrão geográfico no que concerne à biodiversidade global. O coelho-bravo e a raposa foram as espécies mais comuns e de distribuição mais generalizada. No geral, os mamíferos revelaram uma associação a zonas de matagais Mediterrânicos, localizando-se a área prioritária para a sua conservação na zona Central da PPSM. As alterações ou destruição do habitat, a mortalidade nas estradas e a perseguição directa/capturas ilegais foram identificadas como as principais ameaças à conservação dos mamíferos nesta área protegida.
Identificación de las piñas y piñones de pino piñonero (Pinus pinea) abiertos por la ardilla roja (Sciurus vulgaris).
Authors: Arrizabalaga Antoni , Montagud Èlia , Torre Ignasi
Published: September 2024

Se aportaron piñones de P. pinea durante cinco meses en comederos de ardilla y se recogieron los restos para establecer un modelo de apertura por parte de las ardillas. Se contabilizaron un total de 17 tipos de ataques diferentes y se cuantificó su frecuencia. Se recogieron muestras en la naturaleza de conos y piñones manipulados por las ardillas para establecer comparaciones. La ardilla ataca todo tipo de conos de pinos en distintas fases de maduración, incluso el del pino piñonero. Los piñones son abiertos aprovechando la línea de dehiscencia natural que en piñones muy maduros puede ser una pequeña grieta. En este caso no presentan marcas visibles de manipulación y no se distinguen de otros que puedan haberse abierto naturalmente, esto ocurre entre el 72% y el 85% de los piñones comprados y en un 15% de los piñones naturales. Si los piñones están bien cerrados la ardilla roe el ápice hasta producir una muesca a partir de la cual, y por simple presión, los parte en dos. La dificultad en la apertura de algunos piñones y/o la inexperiencia puede incrementar los tipos de ataque y aparecen piñones con dos o tres muescas, así como ataques generalizados en todos sus puntos. Se especula que el incremento del número de tipos de ataques en verano coincide con la época de máxima abundancia de individuos juveniles o subadultos sin experiencia en el tratamiento de los piñones.
Parámetros reproductivos y estructura de edad del zorro Vulpes vulpes (Linnaeus, 1758) en el NE de España: efectos del control de sus poblaciones.
Authors: López-Martín Josep María , Mañas Sisco , López-Claessens Sonia
Published: September 2024

The reproductive parameters, age structure, and sex ratio of red fox Vulpes vulpes from Catalonia (NE Spain) were collected from foxes culled (n= 896) as part of normal activities in hunting areas over 6 consecutive years (1999 to 2004). The samples came from areas with densities above the mean, where culling is legally authorized. Most captures were performed during the first half of the year in 132 private game areas. The total sex ratio was 1:1, and the age structure showed a stable distribution with the highest percentage in age class 0+ and 1+ (56.1%; n= 643). The maximum age found was 8 years. The mean litter size, estimated from placental scars counts and live embryos, was 3.67 (SD= 1.13), ranging up to a maximum of 8, with 3 being the most frequent value. On average, 30.5% of adult females were barren and, including these, the productivity value was 2.59 cubs per adult female. These results are discussed in the framework of culling foxes and game management.
Mastofauna del Bosque Nacional de Buçaco, centro de Portugal.
Authors: Matos Milena , Soares Amadeu , Morgado Fernando , Fonseca Carlos
Published: September 2024

A Mata Nacional do Buçaco (espaço murado com aproximadamente 105 ha) constitui um património natural, histórico e arquitectónico único em Portugal e no Mundo. Biologicamente, representa uma das melhores colecções dendrológicas da Europa, estando associada a esta riqueza florística uma fauna pouco conhecida. O único estudo faunístico deste local foi efectuado há aproximadamente 100 anos consistindo num levantamento e inventariação dos animais presentes nessa época. No presente trabalho procedeu-se à inventariação e determinação da distribuição das espécies de mamíferos (excepto quirópteros) da Mata, através da aplicação de diversos métodos, tais como: observações directas, recolha e identificação de indícios de presença e de cadáveres, realização de prospecções nocturnas, captura de carnívoros e de micromamíferos com armadilhas de caixa e armadilhagem fotográfica e análise de regurgitações de rapinas nocturnas. Confirmou-se a ocorrência de 20 espécies de mamíferos (Insectivora: 4, Rodentia: 8, Carnivora: 7, Artyodactila:1), para as quais foi elaborado um mapa de distribuição na Mata. Salienta-se a ausência de Lagomorfa na Mata, principalmente do coelho-bravo (Oryctolagus cuniculus), espécie presente em todo o território continental, possivelmente devido ao denso e fechado coberto vegetal da Mata. A ocorrência de espécies protegidas como o musaranho-de-dentes-vermelhos (Sorex granarius) e a lontra (Lutra lutra), entre outras, reforça a importância deste espaço no contexto da conservação da mastofauna do país. O conhecimento e a divulgação da biodiversidade presente na Mata Nacional do Buçaco poderão contribuir para a sensibilização dos visitantes deste espaço, no que respeita à protecção do equilíbrio natural e dos ecossistemas presentes, uma vez que é visitada anualmente por mais de 100.000 pessoas.
Avaliaçao da potencialidade do Maciço da Gralheira (Centro-Norte de Portugal) para tres ungulados.
Authors: Lopes Estefania , Neto Vítor , Cancela Jorge , Fonseca Carlos
Published: September 2024

A gestão e o ordenamento das populações de ungulados são desafios crescentes para os gestores cinegéticos. Deste modo, o objectivo do presente trabalho consistiu na determinação da potencialidade do habitat do Maciço da Gralheira (23.990 ha), situado no concelho de São Pedro do Sul (Centro-Norte de Portugal), para três espécies de ungulados (corço Capreolus capreolus, veado Cervus elaphus e javali Sus scrofa), de forma a possibilitar a implementação de um ordenamento e gestão sustentados das suas populações. Neste sentido, desenvolveram-se modelos de avaliação de habitat (HSI) para estas três espécies, utilizando um Sistema de Informação Geográfica (SIG-ArqMap), prevendo-se o impacto de três factores (alimentação, refúgio e tranquilidade) para cada um dos ungulados. Os dados de HSI obtidos foram agrupados em cinco intervalos: [0-0,2±] (muito baixo), [0,2-0,4] (baixo), [0,4-0,6] (médio), [0,6-0,8] (bom) e [0,8-1] (muito bom). Assim, cerca de 77,9% da área total é razoável para o corço, 63,4% para o veado e 74,4% para o javali. Ao intervalo de baixa potencialidade ([0-0,4[) corresponde 18,0% da área, para o corço, 10,5% para o veado e 8,7% para o javali. A restante área potencial encontra-se distribuída pelos intervalos de maior qualidade. No caso dos cervídeos, os intervalos mais elevados correspondem às zonas de pinhal, com um denso e diverso estrato arbustivo e herbáceo, bem como às zonas de folhosas. O factor limitante para os cervídeos é essencialmente a falta de refúgio e, no caso do javali, a baixa disponibilidade alimentar é a condição responsável pela diminuição do potencial do habitat.
The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus
Authors: Li Lei , Wu Guanghao , Xu Xiaolei , Yang Junling , Yi Lirong , Yang Ziqing , Mo Zheng , Xing Li , Shan Ying , Yu Zhuo , Li Yinchuan
Published: September 2024

In this study, we investigated the role of 17α-estradiol in lifespan extension and its potential side effects for long-term administration. Pooled hypothalami from aged male Norway brown rats treated with 17α-estradiol (O.T), aged male controls (O), and young male controls (Y) were subjected to single-nucleus transcriptomic sequencing (snRNA-seq). To evaluate the effects of 17α-estradiol in anti-aging in neurons, supervised clustering on neurons by neuropeptides and their receptors were used to evaluate the responses of each neuron subtype during aging and after 17α-estradiol treatment. The elevated cellular metabolism, stresses and decreased synaptic activity in neurons initiated by aging were remarkably attenuated by 17α-estradiol. Assessment of changes in neuron populations showed that neurons related to food intake, reproduction, blood pressure, stress response and electrolyte balance were sensitive to 17α-estradiol treatment. 17α-estradiol treatment not only increased Oxytocin (Oxt), but also increased the activity of hypothalamic-pituitary-gonadal (HPG) axis, evidenced by significantly elevated levels of plasma Gnrh, bioavailable testosterone, and decreased estradiol. Elevated Gnrh1 was verified to be one of the causal effects mediating the role of 17α-estradiol in energy homeostasis, neural synapse, and stress response. Notably,
Crh
neurons displayed most prominently senescent phenotype among all checked neuron subtypes in O.T, which may be a potential side effect of 17α-estradiol treatment. Therefore, HPG axis and energy metabolism may be key targets of 17α-estradiol in male lifespan extension. Additionally, supervised clustering of neurons was shown to be a useful method to assess the responses to treatment among different neuron subtypes in the hypothalamus.
Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity
Authors: Cox Donal J , Connolly Sarah A , Maoldomhnaigh Cilian Ó , Brugman Aenea AI , Thomas Olivia Sandby , Duffin Emily , Gogan Karl M , Gallchobhair Oisin Ó , Murphy Dearbhla M , O’Rourke Sinead A , O’Connell Finbarr , Nadarajan Parthiban , Phelan James J , Gleeson Laura E , Basdeo Sharee A , Keane Joseph
Published: September 2024

Airway macrophages (AM) are the predominant immune cell in the lung and play a crucial role in preventing infection, making them a target for host directed therapy. Macrophage effector functions are associated with cellular metabolism. A knowledge gap remains in understanding metabolic reprogramming and functional plasticity of distinct human macrophage subpopulations, especially in lung resident AM. We examined tissue-resident AM and monocyte derived macrophages (MDM; as a model of blood derived macrophages) in their resting state and after priming with IFN-γ or IL-4 to model the Th1/Th2 axis in the lung. Human macrophages, regardless of origin, had a strong induction of glycolysis in response to IFN-γ or upon stimulation. IFN-γ significantly enhanced cellular energetics in both AM and MDM by upregulating both glycolysis and oxidative phosphorylation. Upon stimulation, AM do not decrease oxidative phosphorylation unlike MDM which shift to “Warburg”-like metabolism. IFN-γ priming promoted cytokine secretion in AM. Blocking glycolysis with 2-deoxyglucose significantly reduced IFN-γ driven cytokine production in AM, indicating that IFN-γ induces functional plasticity in human AM, which is mechanistically mediated by glycolysis. Directly comparing responses between macrophages, AM were more responsive to IFN-γ priming and dependent on glycolysis for cytokine secretion than MDM. Interestingly, TNF production was under the control of glycolysis in AM and not in MDM. MDM exhibited glycolysis-dependent upregulation of HLA-DR and CD40, whereas IFN-γ upregulated HLA-DR and CD40 on AM independently of glycolysis. These data indicate that human AM are functionally plastic and respond to IFN-γ in a manner distinct from MDM. These data provide evidence that human AM are a tractable target for inhalable immunomodulatory therapies for respiratory diseases.
Psychometric characteristics of the Narcissistic Admiration and Rivalry Questionnaire (NARQ): Arabic version
Authors: Sabah Aiche , Aljaberi Musheer A. , Hamouda Salima , Benamour Djamila , Gadja Keltoum , Lai Yu-Chen , Fang Chuan-Yin , Ali Amira Mohammed , Lin Chung-Ying
Published: September 2024

Narcissists are characterized by confidence, fragility, a desire for social approval without showing interest in others, charm, self-assurance, arrogance, and aggression. This study assesses the psychometric properties of the Arabic version of the Narcissistic Admiration and Rivalry Questionnaire (NARQ) among Algerian students (N = 714). Confirmatory factor and Rasch analyses were used. The NARQ consists of 18 items addressing six narcissism subscales under two main dimensions: rivalry and admiration. The results showed good saturation of the items on the six subscales and the three sub-scales on each of the two main dimensions, revealing a modest but positive correlation between rivalry and admiration. Moreover, the results of the Rasch model demonstrated that the scale aligns with the data, confirming the validity of the scale. This study offers valuable perspectives on assessing narcissism among Arabic populations and enhances our comprehension of the traits linked to narcissistic personalities.
Valorización de los Materiales del Bosque Nativo a Través del Diseño de Elementos Arquitectónicos: Manejo y Uso Sostenible del Bosque Nativo
Authors:   , Saenz Orrego Trinidad Francisca
Published: September 2024

En Panguipulli el Bosque Nativo abarca el 64,5% de la superficie comunal, sin embargo, la mayoría de estos bosques se encuentran degradados. La degradación es un proceso causado por la intervención humana que implica la pérdida de la productividad, biodiversidad y estructura de los ecosistemas forestales, siendo una de las principales amenazas para el bosque nativo de la zona. Esta situación se debe en gran medida a la falta de conciencia e incentivos para el manejo y uso sostenibles por parte de sus propietarios. Una de las principales causas de la degradación del bosque es su descuido debido a la falta de ingresos que éste significa para sus propietarios, por lo tanto, para su recuperación, se deben buscar formas que permitan hacer uso de sus recursos de manera sostenible, que signifiquen un aporte para sus propietarios, siendo así un incentivo para su cuidado y manejo.Para esto se identificaron distintos materiales provenientes del bosque nativo de la zona de Panguipulli que pueden ser obtenidos a partir de los procesos de manejo sostenible con los cuales se crearon elementos arquitectónicos de alto valor con el objetivo de agregar valor a estos materiales y generar un mercado sostenible que sirva de incentivo para el manejo del bosque para sus propietarios.Esto es posible debido a que existen en la zona de Panguipulli técnicas artesanales como la carpintería y cestería que son capaces de aprovechar los distintos componentes del bosque (maderables o no) de manera sostenible, con las que se pueden confeccionar elementos arquitectónicos y sistemas constructivos innovadores, los cuales son una manera efectiva de agregar valor a los productos provenientes del manejo sostenible del bosque nativo, beneficiando así a sus propietarios y comunidades locales a la vez que se incentiva el cuidado y manejo sostenible del bosque.Palabras clave: bosque nativo, manejo sostenible, innovación, productos de alto valor.
An experiment in near field cosmology: A search for the Magellanic Wake
Authors:   , Cavieres Carrera Manuel Antonio
Published: September 2024

The infall of the Magellanic Cloud system into the Milky Way halo hasstrong effects on the distribution of the stars and dark matter in the outerhalo of our Galaxy. In particular, N-body simulations predict a large-scaledensity asymmetry that spans the northern Galactic hemisphere (known as thecollective response), along with a localized overdensity (the Wake) that trailsthe LMC’s orbit. In this study, we collected wide-field deep near-infrared andoptical photometry from the VISTA and DECam instruments in four fieldsalong the expected position of the Magellanic Wake, covering most of thedensity range predicted to be found in the outer halo, as predicted by numericalmodels. This data allows us to select a clean sample of halo stars that reachthe oldest main sequence turn-off (MSTO) up to 100 kpc, with ∼ 400 stellarsources further than 60 kpc, on two separate tracers, near main sequence turnoff stars and red giant branch. We found that the Magellanic Wake overdensityis present in our data with a relative overdensity of 3.07 ± 0.7. Comparisonof the radial density profiles of near-MSTO stars with simulations of the MilkyWay/LMC interaction is best fitted by a massive LMC model with a total massof 2.5 × 10^11M⊙. This work provides the first unambiguous detection of thewake with consistent densities between two tracers.
Orientaciones para la evaluación progresiva del logro del perfil de egreso en la Universidad Tecnológica Metropolitana
Authors:   , Inzunza Herrera Javiera Paz
Published: September 2024

En el marco de la calidad de la educación y el mejoramiento continuo de las instituciones de educación superior y de los procesos educativos, la evaluación curricular toma fuerza como área de investigación y componente esencial para el aseguramiento de la calidad. El trabajo aborda la evaluación del currículum desde su dimensión intrínseca, específicamente, la evaluación del cumplimiento del logro del perfil de egreso dentro del “tejido curricular”. El trabajo, desde un enfoque cualitativo, consideró el análisis de las estrategias de evaluación del perfil de egreso que ha instalado la Universidad Tecnológica Metropolitana, a través de revisión documental, entrevistas semiestructuradas y, un análisis mediante técnicas de codificación y comparación. La intención es indagar en estos procesos, entregar orientaciones de mejora para el levantamiento de un sistema de evaluación del logro del perfil de egreso y promover la evaluación curricular como una pieza inherente a la mejora continua del proceso educativo y entregar información relevante para la toma de decisiones institucionales.
A Comprehensive Review of Pests, Pesticides and Residue Detection Techniques in Mushroom
Authors: B Tulasi , K Bhuvaneswari , Manideep Sake , Kumar Sai , C Selvi , Nagarani Ch , D Thrilekha
Published: September 2024

Mushrooms are valued for their dietary benefits and medicinal properties, being rich in proteins, minerals, vitamins, fiber, and essential amino acids. They offer significant health benefits, including the prevention of hypercholesterolemia and cardiovascular diseases, and possess antitumor, antiviral, antihypertensive, anti-inflammatory, and immunomodulating properties. Global mushroom production has seen substantial growth, particularly in Asia. However, mushroom cultivation is challenged by various insect pests, leading to significant crop losses. Pesticides are frequently applied to control pests in mushroom cultivation, but their use can lead to the presence of pesticide residues in the mushrooms, raising concerns about food safety. To detect these low levels of residues, multiresidue analytical methods are crucial. Among these, the QuEChERS method stands out as the most commonly used due to its sensitivity, selectivity, and accuracy in determining multiple pesticide residues simultaneously. These methods are capable of identifying various pesticide compounds in a single analysis, effectively addressing the specific biological characteristics of mushrooms. The maximum residue levels (MRLs) for pesticide residues in mushrooms differ, with strict guidelines enforced by regulatory authorities. This paper provides a comprehensive review of the pests that affect mushroom cultivation, the pesticides utilized, and the analytical techniques developed for the detection of pesticide residues in mushrooms.
The Effect of Tax Awareness, Tax Understanding, and Tax Morals on Taxpayer Compliance from the Gender Perspective of MSME Entrepreneurs in the Tanah Abang Market
Authors: Suherdi Viona , Tarmidi Deden
Published: September 2024

Aims: This study aims to determine the effect of tax awareness, tax understanding, and tax morals on taxpayer compliance from the gender point of view of MSME entrepreneurs.
Study Design: The research design used is a survey by distributing questionnaires directly to respondents or MSE taxpayers in the Tanah Abang Market. The sample collection technique used in this study was simple random sampling.
Place and Duration of Study: The sample in this study were MSME taxpayers in the Tanah Abang Market as many as 154 male respondents and 116 female respondents.
Methodology: Researchers used the Hair et al. formula [1] to determine the number of research samples. The type of data used in this study is quantitative data in the form of values or scores for the answers given by MSME respondents in the Jakarta Tanah Abang Market to the questions in the questionnaire. The data obtained was transferred into data tabulation and analyzed using PLS-SEM (Partial Least Squares Structural Equation Modeling) software version 4.0 to generate a hypothesis of a causal relationship between the independent variables (tax awareness, tax understanding, and tax morale) and the dependent variable (taxpayer compliance).
Results: The results of the study are tax awareness, tax understanding, and tax morale have a significant influence on the compliance of male and female taxpayers.
Conclusion: From this study, it was found that in combination gender, tax awareness, tax understanding, and tax morale had an effect on taxpayer compliance. However, based on the significance value, it is known that tax awareness and tax understanding of females have a more significant effect on tax compliance than males. This is different from tax morale, based on the significance value, it is known that male tax morale has a more significant effect than female. This is in line with Gender theory which explains the differentiation of roles, positions, responsibilities, and division of labor between men and women determined by society based on the nature of women and men who are considered appropriate in accordance with the norms, customs, beliefs or habits of society [2].
Interannual stability of organic to inorganic carbon production on a coral atoll
Authors: Kwiatkowski Lester , Albright Rebecca , Hosfelt Jessica , Nebuchina Yana , Ninokawa Aaron , Rivlin Tanya , Sesboüé Marine , Wolfe Kennedy , Caldeira Ken
Published: April 2016

Ocean acidification has the potential to adversely affect marine calcifying organisms, with substantial ocean ecosystem impacts projected over the 21st century. Characterizing the in situ sensitivity of calcifying ecosystems to natural variability in carbonate chemistry may improve our understanding of the long‐term impacts of ocean acidification. We explore the potential for intensive temporal sampling to isolate the influence of carbonate chemistry on community calcification rates of a coral reef and compare the ratio of organic to inorganic carbon production to previous studies at the same location. Even with intensive temporal sampling, community calcification displays only a weak dependence on carbonate chemistry variability. However, across three years of sampling, the ratio of organic to inorganic carbon production is highly consistent. Although further work is required to quantify the spatial variability associated with such ratios, this suggests that these measurements have the potential to indicate the response of coral reefs to ongoing disturbance, ocean acidification, and climate change.
Combined scattering loss of radiation belt relativistic electrons by simultaneous three‐band EMIC waves: A case study
Authors: He Fengming , Cao Xing , Ni Binbin , Xiang Zheng , Zhou Chen , Gu Xudong , Zhao Zhengyu , Shi Run , Wang Qi
Published: April 2016

Multiband electromagnetic ion cyclotron (EMIC) waves can drive efficient scattering loss of radiation belt relativistic electrons. However, it is statistically uncommon to capture the three bands of EMIC waves concurrently. Utilizing data from the Electric and Magnetic Field Instrument Suite and Integrated Science magnetometer onboard Van Allen Probe A, we report the simultaneous presence of three (H+, He+, and O+) emission bands in an EMIC wave event, which provides an opportunity to look into the combined scattering effect of all EMIC emissions and the relative roles of each band in diffusing radiation belt relativistic electrons under realistic circumstances. Our quantitative results, obtained by quasi‐linear diffusion rate computations and 1‐D pure pitch angle diffusion simulations, demonstrate that the combined resonant scattering by the simultaneous three‐band EMIC waves is overall dominated by He+ band wave diffusion, mainly due to its dominance over the wave power (the mean wave amplitudes are approximately 0.4 nT, 1.6 nT, and 0.15 nT for H+, He+, and O+ bands, respectively). Near the loss cone, while 2–3 MeV electrons undergo pitch angle scattering at a rate of the order of 10−6–10−5 s−1, 5–10 MeV electrons can be diffused more efficiently at a rate of the order of 10−3–10−2 s−1, which approaches the strong diffusion level and results in a moderately or heavily filled loss cone for the atmospheric loss. The corresponding electron loss timescales (i.e., lifetimes) vary from several days at the energies of ~2 MeV to less than 1 h at ~10 MeV. This case study indicates the leading contribution of He+ band waves to radiation belt relativistic electron losses during the coexistence of three EMIC wave bands and suggests that the roles of different EMIC wave bands in the relativistic electron dynamics should be carefully incorporated in future modeling efforts.
A meta‐analysis of studies investigating the effects of occupational lead exposure on thyroid hormones
Authors: Krieg Edward F.
Published: April 2016

Introduction

Investigations of the effects of occupational exposure to lead on the concentrations of thyroid hormones in the blood have not produced consistent results. A meta‐analysis was performed to assess the effect of occupational exposure to lead on thyroid hormone concentrations using the results from published studies.

Methods

Group means from studies of the thyroid function of persons occupationally exposed to lead were used in a meta‐analysis. Differences between the control and exposed groups, and the slopes between thyroid hormone concentrations and log10 blood lead concentrations or duration of exposure to lead were estimated using mixed models. The hormones analyzed were thyroid stimulating hormone, total and free thyroxine, and total and free triiodothyronine.

Results

No differences in mean thyroid hormone concentrations were found between the exposed and control groups. No relationships were found between blood lead or the duration of exposure to lead and thyroid hormone concentrations.

Conclusion

The results of the analysis do not provide evidence for an effect of occupational lead exposure on thyroid function in men. Am. J. Ind. Med. 59:583–590, 2016. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.
Occupational exposures to engine exhausts and other PAHs and breast cancer risk: A population‐based case‐control study
Authors: Rai Rajni , Glass Deborah C. , Heyworth Jane S. , Saunders Christobel , Fritschi Lin
Published: April 2016

Background

Some previous studies have suggested that exposure to engine exhausts may increase risk of breast cancer.

Methods

In a population‐based case‐control study of breast cancer in Western Australia we assessed occupational exposure to engine exhausts using questionnaires and telephone interviews. Odds Ratios (OR) and 95% Confidence Intervals (CI) were calculated using logistic regression.

Results

We found no association between risk of breast cancer and occupational exposure to diesel exhaust (OR 1.07, 95%CI: 0.81–1.41), gasoline exhaust (OR 0.98, 95%CI: 0.74–1.28), or other exhausts (OR 1.08, 95%CI: 0.29–4.08). There were also no significant dose‐ or duration‐response relationships.

Conclusions

This study did not find evidence supporting the association between occupational exposures to engine exhausts and breast cancer risk. Am. J. Ind. Med. 59:437–444, 2016. © 2016 Wiley Periodicals, Inc.
The Planar CoB18− Cluster as a Motif for Metallo‐Borophenes
Authors: Li Wan‐Lu , Jian Tian , Chen Xin , Chen Teng‐Teng , Lopez Gary V. , Li Jun , Wang Lai‐Sheng
Published: April 2016

Monolayer‐boron (borophene) has been predicted with various atomic arrangements consisting of a triangular boron lattice with hexagonal vacancies. Its viability was confirmed by the observation of a planar hexagonal B36 cluster with a central six‐membered ring. Here we report a planar boron cluster doped with a transition‐metal atom in the boron network (CoB18−), suggesting the prospect of forming stable hetero‐borophenes. The CoB18− cluster was characterized by photoelectron spectroscopy and quantum chemistry calculations, showing that its most stable structure is planar with the Co atom as an integral part of a triangular boron lattice. Chemical bonding analyses show that the planar CoB18− is aromatic with ten π‐electrons and the Co atom has strong covalent interactions with the surrounding boron atoms. The current result suggests that transition metals can be doped into the planes of borophenes to create metallo‐borophenes, opening vast opportunities to design hetero‐borophenes with tunable chemical, magnetic, and optical properties.
Synthesis of Highly Uniform Molybdenum–Glycerate Spheres and Their Conversion into Hierarchical MoS2 Hollow Nanospheres for Lithium‐Ion Batteries
Authors: Wang Yawen , Yu Le , Lou Xiong Wen (David)
Published: April 2016

Highly uniform Mo–glycerate solid spheres are synthesized for the first time through a solvothermal process. The size of these Mo–glycerate spheres can be easily controlled in the range of 400–1000 nm by varying the water content in the mixed solvent. As a precursor, these Mo–glycerate solid spheres can be converted into hierarchical MoS2 hollow nanospheres through a subsequent sulfidation reaction. Owing to the unique ultrathin subunits and hollow interior, the as‐prepared MoS2 hollow nanospheres exhibit appealing performance as the anode material for lithium‐ion batteries. Impressively, these hierarchical structures deliver a high capacity of about 1100 mAh g−1 at 0.5 A g−1 with good rate retention and long cycle life.
Unusually Short Be−Be Distances with and without a Bond in Be2F2and in the Molecular Discuses Be2B8and Be2B7−
Authors: Cui Zhong‐hua , Yang Wen‐sheng , Zhao Lili , Ding Yi‐hong , Frenking Gernot
Published: April 2016

Quantum‐chemical calculations at the CCSD(T)/cc‐pVTZ level of theory show that beryllium subfluoride, Be2F2, has a bond dissociation energy ofDe=76.9 kcal mol−1, which sets a record for the strongest Be−Be bond. The synthesis of this molecule should thus be possible in a low‐temperature matrix. The discus‐shaped species Be2B8and Be2B7−possess the shortest Be–Be distance for a molecule in the electronic ground state, but there is no Be−Be bond. The cyclic species Be2B8and Be2B7−exhibit double aromaticity with 6σ and 6π electrons, which strongly bind the Be2fragment to the boron atoms. The very short interatomic distance between the beryllium atoms is due to the Be−B σ and π bonds, which operate like spokes in a wheel pressing the beryllium atoms together. The formation of the Be−B bonds has effectively removed the electronic charge of the valence space between the beryllium atoms. Along the Be–Be axis, there are two cage critical points adjacent to a ring critical point at the midpoint, but there is no bond critical point and no bond path.
Placenta accreta following hysteroscopic myomectomy
Authors: Tanaka Mie , Matsuzaki Shinya , Matsuzaki Satoko , Kakigano Aiko , Kumasawa Keiichi , Ueda Yutaka , Endo Masayuki , Kimura Tadashi
Published: April 2016

Key Clinical Message

Hardly any report exists on the influence of hysteroscopic myomectomy on subsequent pregnancy. Placenta accreta is most often associated with placenta previa in women with multiple prior cesarean sections. We report the first case of placenta accreta without placenta previa during the first pregnancy subsequent to hysteroscopic myomectomy.