bluuebunny/crossref_metadata_2025 huggingface dataset:
Hatching egg polyunsaturated fatty acids and the broiler chick
Authors: Cherian Gita
Published: September 2022

Transgenerational effects of certain nutrients such as essential fatty acids are gaining increased attention in the field of human medicine and animal sciences as a new tool to improve health and animal performance during perinatal life. Omega-3 (n-3) and omega-6 (n-6) fatty acids are denoted by the position of the first double bond from methyl end of the hydrocarbon chain. Alpha-linolenic acid (18:3 n-3) and linoleic acid (18:2 n-6) are essential n-3 and n-6 fatty acids and cannot be synthesized by the vertebrates including chickens. Alpha-linolenic acid and linoleic acid are the parent fatty acids of long chain (> 20–22C) n-3 and n-6 polyunsaturated fatty acids (PUFA) such as eicosapentaenoic acid (20:5 n-3, EPA), docosapentaenoic acid (22:5 n-3/or 22:5 n-6, DPA), docosahexaenoic acid (22:6 n-3, DHA) and arachidonic acid (20:4 n-6). As components of cell membrane phospholipids, PUFA serves as precursors of eicosanoids, act as ligands for membrane receptors and transcription factors that regulate gene expression and are pivotal for normal chick growth and development. Considering the role of egg lipids as the sole source of essential fatty acids to the hatchling, dietary deficiencies or inadequate in ovo supply may have repercussions in tissue PUFA incorporation, lipid metabolism, chick growth and development during pre and early post-hatch period. This review focus on studies showing how maternal dietary n-3 or n-6 fatty acids can lead to remodeling of long chain n-3 and n-6 PUFA in the hatching egg and progeny chick tissue phospholipid molecular species and its impact on chick growth and PUFA metabolism during early life.
Development and validation of an early warning model for hospitalized COVID-19 patients: a multi-center retrospective cohort study
Authors: Smit Jim M. , Krijthe Jesse H. , Tintu Andrei N. , Endeman Henrik , Ludikhuize Jeroen , van Genderen Michel E. , Hassan Shermarke , El Moussaoui Rachida , Westerweel Peter E. , Goekoop Robbert J. , Waverijn Geeke , Verheijen Tim , den Hollander Jan G. , de Boer Mark G. J. , Gommers Diederik A. M. P. J. , van der Vlies Robin , Schellings Mark , Carels Regina A. , van Nieuwkoop Cees , Arbous Sesmu M. , van Bommel Jasper , Knevel Rachel , de Rijke Yolanda B. , Reinders Marcel J. T.
Published: September 2022

Background

Timely identification of deteriorating COVID-19 patients is needed to guide changes in clinical management and admission to intensive care units (ICUs). There is significant concern that widely used Early warning scores (EWSs) underestimate illness severity in COVID-19 patients and therefore, we developed an early warning model specifically for COVID-19 patients.

Methods

We retrospectively collected electronic medical record data to extract predictors and used these to fit a random forest model. To simulate the situation in which the model would have been developed after the first and implemented during the second COVID-19 ‘wave’ in the Netherlands, we performed a temporal validation by splitting all included patients into groups admitted before and after August 1, 2020. Furthermore, we propose a method for dynamic model updating to retain model performance over time. We evaluated model discrimination and calibration, performed a decision curve analysis, and quantified the importance of predictors using SHapley Additive exPlanations values.

Results

We included 3514 COVID-19 patient admissions from six Dutch hospitals between February 2020 and May 2021, and included a total of 18 predictors for model fitting. The model showed a higher discriminative performance in terms of partial area under the receiver operating characteristic curve (0.82 [0.80–0.84]) compared to the National early warning score (0.72 [0.69–0.74]) and the Modified early warning score (0.67 [0.65–0.69]), a greater net benefit over a range of clinically relevant model thresholds, and relatively good calibration (intercept = 0.03 [− 0.09 to 0.14], slope = 0.79 [0.73–0.86]).

Conclusions

This study shows the potential benefit of moving from early warning models for the general inpatient population to models for specific patient groups. Further (independent) validation of the model is needed.
An integrated microfluidics platform with high-throughput single-cell cloning array and concentration gradient generator for efficient cancer drug effect screening
Authors: Wang Biao , He Bang-Shun , Ruan Xiao-Lan , Zhu Jiang , Hu Rui , Wang Jie , Li Ying , Yang Yun-Huang , Liu Mai-Li
Published: September 2022

Background

Tumor cell heterogeneity mediated drug resistance has been recognized as the stumbling block of cancer treatment. Elucidating the cytotoxicity of anticancer drugs at single-cell level in a high-throughput way is thus of great value for developing precision therapy. However, current techniques suffer from limitations in dynamically characterizing the responses of thousands of single cells or cell clones presented to multiple drug conditions.

Methods

We developed a new microfluidics-based “SMART” platform that is Simple to operate, able to generate a Massive single-cell array and Multiplex drug concentrations, capable of keeping cells Alive, Retainable and Trackable in the microchambers. These features are achieved by integrating a Microfluidic chamber Array (4320 units) and a six-Concentration gradient generator (MAC), which enables highly efficient analysis of leukemia drug effects on single cells and cell clones in a high-throughput way.

Results

A simple procedure produces 6 on-chip drug gradients to treat more than 3000 single cells or single-cell derived clones and thus allows an efficient and precise analysis of cell heterogeneity. The statistic results reveal that Imatinib (Ima) and Resveratrol (Res) combination treatment on single cells or clones is much more efficient than Ima or Res single drug treatment, indicated by the markedly reduced half maximal inhibitory concentration (IC50). Additionally, single-cell derived clones demonstrate a higher IC50 in each drug treatment compared to single cells. Moreover, primary cells isolated from two leukemia patients are also found with apparent heterogeneity upon drug treatment on MAC.

Conclusion

This microfluidics-based “SMART” platform allows high-throughput single-cell capture and culture, dynamic drug-gradient treatment and cell response monitoring, which represents a new approach to efficiently investigate anticancer drug effects and should benefit drug discovery for leukemia and other cancers.
Computer-guided buccal cortical plate separation for removal of calcified benign odontogenic tumors affecting the mandibular angle region
Authors: Omara Mohammed , Gouda Ayman , Ali Sherif
Published: September 2022

Purpose

Surgical removal of intra-bony calcific benign lesions is technically challenging regarding its accessibility, proximity to vital structures, and deteriorating effect on the remaining bony structures.

Methods

Computer-guided buccal cortical plate separation was performed for ten patients using patient-specific osteotomy locating guides and pre-bent plates. The guide was designed to outline the osteotomy, the buccal cortical plate was separated, the lesion was removed, and finally, the pre-bent plates were used to fix the separated cortex.

Results

Surgical procedures were uneventful for all patients, operation time was 39.5 ± 13.01 min, postoperative pain decreased within the follow-up time intervals, and there was a statistical significant difference between the time intervals (P value < 0.001). Edema and trismus were acceptable. One case showed nerve affection which resolved after 4 weeks.

Conclusion

Computer-guided buccal cortical plate separation for removal of intra-bony calcified benign lesions provides a promising approach, especially for inexperienced surgeons.

Trial registration

ClinicalTrials.gov NCT05329974. Registered on 6 April 2022—retrospectively registered.
Mini-temporal approach as an alternative to the classical pterional approach for resective temporal region surgeries
Authors: Kudulaiti Nijiati , Liu Feili , Hameed N. U. Farrukh , Wang Peng , Zhang Jie , Feng Rui , Wu Jinsong
Published: September 2022

Background

Classical pterional appoach for temporal surgeries may cause atrophy and dysfunction of temporalis, injury to the facial nerve, and unnecessary cortical exposure. As an alternative to the classical pterional approach for such surgeries, we hereby describe an mini-temporal approach which reduces these risks and proven to be practical in neurological surgeries.

Material and methods

In the mini-temporal incision design, the frontal end of the incision never surpassed the hairline at the level of temporal line, and a one-layer skin-galea-muscle flap was detached from the cranium, effectively avoiding the injuries of facial nerve. The surgical bone window was completely located underneath the temporalis muscle, allowing it to be completely repositioned postoperatively.

Results

We demonstrated the application of mini-temporal approach in a variety of temporal region tumors, which can be applied to complete successful resective surgeries while effectively reducing injuries to extra-temporal cortex, temporalis, and facial nerve. There were no postoperative complications related to extra-temporal cortical damage, atrophy of temporalis, or injury to the facial nerve.

Conclusion

The mini-temporal approach can effectively shorten the time of craniotomy and closure, decrease the size of bony removal, increase the restoration of temporalis during closure, and lower the chance of facial nerve injury. Therefore, it improves cosmetic outcomes and reduces the risk of unintentional extra-temporal cortical injury, which fully embodies the minimally invasive principle in neurosurgery.
Test–retest reliability and measurement error of the WHO-5 Well-being Index and the Problem Areas in Diabetes questionnaire (PAID) used in telehealth among patients with type 1 diabetes
Authors: Schougaard Liv Marit Valen , Laurberg Tinne , Lomborg Kirsten , Hansen Troels Krarup , Hjollund Niels Henrik , Jensen Annesofie Lunde
Published: September 2022

Background

Patient-reported outcome (PRO) measures may be used in telehealth for the clinical assessment of mental health and diabetes distress, which are important aspects in diabetes care, but valid and reliable instruments on these topics are necessary. We aimed to evaluate the test–retest reliability and measurement error of the Danish versions of the WHO-Five Well-being Index (WHO-5) and Problem Areas in Diabetes (PAID) questionnaires used in a PRO-based telehealth intervention among patients with type 1 diabetes. A further aim was to evaluate the test–retest reliability of single items concerning patients’ symptom burden and general health status.

Methods

Outpatients with type 1 diabetes from the Steno Diabetes Center Aarhus, Aarhus University Hospital, Denmark, were enrolled from April 2019 to June 2020. Patients aged ≥ 18 who had type 1 diabetes for > 1 year, internet access, and the ability to understand, read, and write Danish were included. Intraclass correlation coefficients (ICC) and weighted Kappa values were used to assess test–retest reliability, and measurement error was assessed by estimating the minimal detectable change (MDC).

Results

A total of 146/255 (57%) patients completed the web questionnaire twice. The median response time between the two-time points was five days. The ICC of the WHO-5 scale was 0.87 (95% CI 0.82–0.90), and MDC was 18.56 points (95% CI 16.65–20.99). The ICC of the PAID scale was 0.89 (95% CI 0.84–0.92), and MDC was 11.86 points (95% CI 10.46–13.70). Overall, test–retest reliability of single symptoms and general health status items was substantial.

Conclusions

The WHO-5 and PAID questionnaires, and single symptoms and general health status items showed substantial test–retest reliability among patients with type 1 diabetes. Measurement error of the PAID questionnaire was considered acceptable; however, a larger measurement error of the WHO-5 questionnaire was observed. Further research is recommended to explore these findings.
Functional Assessment of Chronic Illness Therapy-Fatigue is a reliable and valid measure in patients with active ankylosing spondylitis
Authors: Cella David , Lenderking William R. , Chongpinitchai Peter , Bushmakin Andrew G. , Dina Oluwaseyi , Wang Lisy , Cappelleri Joseph C. , Navarro-Compán Victoria
Published: September 2022

Background

The Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) scale has demonstrated good internal consistency and responsiveness to changes in clinical status among patients with ankylosing spondylitis (AS). We aimed to further evaluate the psychometric properties of the FACIT-F scale in adult patients with AS.

Methods

Measurement properties of the FACIT-F scale were evaluated using data from tofacitinib phase 2/3 (NCT01786668/NCT03502616) studies in adult patients with active AS.

Results

Second-order confirmatory factor modeling supported the measurement structure of the FACIT-F scale (Bentler’s comparative fit index ≥ 0.91), and FACIT-F demonstrated excellent internal consistency (Cronbach’s coefficient α ≥ 0.88) and test–retest reliability (Intraclass Correlation Coefficient ≥ 0.75). Correlation coefficients between FACIT-F and other patient-reported outcomes generally exceeded 0.40, supporting convergent validity. Meaningful within-patient change was estimated as 3.1–6.3 for FACIT-F total score, and 1.4–2.8 and 1.7–3.6 for FACIT-F Experience and Impact domain scores, respectively. Large (effect size ≥ 1.17 standard deviation units), statistically significant differences in FACIT-F domain/total scores between ‘no disease activity’ (Patient Global Assessment of Disease Activity [PtGA] = 0) and ‘very active disease’ (PtGA = 10) patient groups supported known-groups validity. Ability to detect change was evidenced by an approximately linear relationship between changes in FACIT-F and PtGA scores.

Conclusions

FACIT-F is a reliable and valid measure for evaluating fatigue in adult patients with active AS.

Trial registration: ClinicalTrials.gov; NCT01786668 (registered 6 February 2013, https://clinicaltrials.gov/ct2/show/NCT01786668) and NCT03502616 (registered 11 April 2018, https://clinicaltrials.gov/ct2/show/NCT03502616).
Electronic patient-reported outcomes (e-PROMs) in palliative cancer care: a scoping review
Authors: Consolo Letteria , Castellini Greta , Cilluffo Silvia , Basile Ilaria , Lusignani Maura
Published: September 2022

Background

In palliative oncology settings, electronic patient-reported outcome (PRO) assessment can play an important role in supporting clinical activities for clinicians and patients. This scoping review aims to map the technological innovation of electronic patient-reported outcome measures (e-PROMs) in cancer palliative care and how PRO data collected through e-PROMs can influence the monitoring and management of symptoms and enable better communication between health professionals and patients.

Methods

A scoping review study was designed according to the Arksey and O'Malley framework. Medline, Embase, Web of Science, SCOPUS, PsycINFO and CINAHL and gray literature sources were consulted. The inclusion criteria were people over 18 years old receiving palliative and/or end-of-life care using e-PROMs.

Results

Thirteen primary studies were included: nine quantitative studies, two qualitative studies, and two mixed-method studies. The recently developed software that supports e-PROMs allows patients to receive feedback on their symptoms, helps clinicians prioritize care needs and monitors patients’ conditions as their symptoms change. Electronic PRO data prompt difficult, end-of-life communication between clinicians and patients to better organize care in the last phase of life.

Conclusion

This work shows that electronic PRO data assessment provides valuable tools for patients’ well-being and the management of symptoms; only one study reported conflicting results. However, with studies lacking on how clinicians can use these tools to improve communication with patients, more research is needed.
Misconceiving patient reported outcome measures (PROMs) as primarily a reporting requirement rather than a quality improvement tool: perceptions of independent healthcare sector stakeholders in the UK
Authors: Anderson Michael , Pitchforth Emma , Vallance-Owen Andrew , Mossialos Elias , Millner Paul , Fistein Jon
Published: September 2022

Background

The independent healthcare sector in the UK collects PROMs for several surgical procedures, but implementation has been challenging. We aimed to understand the enablers and barriers to PROMs implementation in the independent healthcare sector in the UK.

Method

Between January and May 2021, we remotely conducted semi-structured interviews with hospital consultants, hospital managers and other clinical staff using a topic guide developed from an implementation science framework called the Theoretical Domains Framework (TDF).

Results

We interviewed 6 hospital consultants, 5 hospital managers, and 3 other clinical staff (1 nurse and 2 physiotherapists) across 8 hospitals. Common barriers included: the perception that PROMs are predominantly a reporting requirement rather than a quality improvement tool, absence of feedback mechanisms for PROMs data for clinicians, poor awareness of PROMs among healthcare professionals and the public, absence of direction or commitment from leadership, and limited support from hospital consultants. Common enablers included: regular feedback of PROMs data to clinicians, designating roles and responsibilities, formally embedding PROMs collection into patient pathways, and involvement of hospital consultants in developing strategies to improve PROMs uptake.

Conclusion

To support PROMs implementation, independent hospitals need to develop long-term organisational strategies that involve sustained leadership commitment, goals or targets, training opportunities to staff, and regular feedback of PROMs data at clinical or governance meetings. The primary purpose of PROMs needs to be reframed to independent healthcare sector stakeholders as a quality improvement tool rather than a reporting requirement.
A review on intraspecific karyomorphological variations of m chromosomes in family Libellulidae (Anisoptera: Odonata)
Authors: Walia Gurinder Kaur , Singh Hardeep
Published: September 2022

Background

Family Libellulidae is one of the largest families of suborder Anisoptera (Odonata) including 1035 species of 144 genera throughout the world. Libellulids are distributed all around the globe, while some are cosmopolitan and some are endemic. Cytogenetic data pertains to 258 libellulid species and chromosome number varies from 2n = 6–47. Majority of the species possess 2n (♂) = 25, which is the modal number of the family. The m chromosomes are considered as the fragments of autosomes and are present in 78% of studied libellulid species.

Main body

Presently, 29 libellulid species have been catalogued based on various research articles related to cytogenetic studies regarding intraspecific chromosomal variations especially due to the m chromosomes within the same or different geographical populations of the species.

Conclusions

Odonata possess holokinetic chromosomes and m chromosomes are the fragments of autosome. The break can occur at any time, at any place, which is responsible for variations in the size of m chromosomes. These variations also depend on the geographical distribution of the species which persists over generations by the action of natural selection and also play role in speciation.
The influence of ethnic identity on peruvian quinoa consumption: a top lima and modern metropolitan lima approach
Authors: Higuchi Angie , Morales L. Emilio , Sánchez-Pérez L. A. , Maehara Rocío
Published: September 2022

The International Year of Quinoa (IYQ) (2013) showcased quinoa to the world and generated a rapid expansion in international demand for quinoa. It also increased the level of consumption in Peru. Peruvian ethnic identity reflects the food culture of origin. This research aims to determine the relationship between ethnic identity and other Theory of Planned Behavior factors on quinoa consumption intention and frequency of consumers in Top Lima and Modern Metropolitan Lima, Peru. A survey of 381 respondents was conducted between April and September 2017, and structural equation modeling was used to analyze the data. Contrary to expectations, intention and frequency of consumption of quinoa were negatively affected by “ethnic identity” (p < 0.05). This result is related to the promotion by the IYQ and Marca Perú (brand name Peru) and the gastronomic boom.
Prevalence of anxiety and depression among Palestinian university students: a cross-sectional study during COVID-19 pandemic
Authors: Ghanim Mustafa , Rabayaa Maha , Atout Sameeha , Al-Othman Nihad , Alqub Malik
Published: September 2022

Background

Anxiety and depression are more common among university students than in the general population. It is reported internationally that the COVID-19 pandemic increased the prevalence of anxiety and depression among students. This study aimed to measure the prevalence of anxiety and depression among university students in Palestine and to explore the association between anxiety and depression during the COVID-19 pandemic. A cross-sectional questionnaire-based descriptive study was carried out on university students. The Generalized Anxiety Disorder Scale (GAD-7) and the Center for Epidemiological Studies Depression (CES-D) scale were used to evaluate anxiety and depression, respectively. Chi-square was used to evaluate the risk factors associated with the levels of anxiety and depression. The association between anxiety and depression was evaluated using Pearson correlation.

Results

A total of 1049 students were enrolled in the study. The prevalence of depression among them was 55.8%, 26.4%, and 9.8% for severe, moderate, and mild depression, respectively. Depression symptoms were significantly variable based on students’ field and year of study, sleeping period, smoking, and food source. The prevalence of anxiety was 16.1%, 30.7%, and 36.1% for severe, moderate, and mild anxiety, respectively. Anxiety symptoms were significantly variable based on students’ gender, year of study, sleeping period, smoking, and place of residence. A strong positive correlation was observed between the CES-D and GAD-7 scores (R = 0.707).

Conclusion

Palestinian university students suffer from elevated levels of anxiety and depression during the COVID-19 pandemic. This necessitates the need for strategies by stakeholders to take immediate and appropriate interventions.
Adult attention-deficit hyperactivity disorder among patients with substance use disorders
Authors: Effat Safeya , Elshahawi Heba , Refaat Ghada , Rabie Menan , Nasr Ashraf , Elrassas Hanan
Published: September 2022

Background

Attention-deficit/hyperactivity disorder (ADHD) is a childhood neurodevelopmental disorder that persists into adulthood. ADHD is a well-known risk factor for substance use disorder (SUD). However, the actual contribution of comorbidity is largely unknown. The current study investigated the prevalence of ADHD in a sample of abstinent patients compared to healthy controls.

Compared to 51 healthy controls, 51 patients seeking medical treatment for SUD were abstinent from any substance for at least 1 month, interviewed by the use of the ICD-10 symptom checklist, the Social Classification Scale, the Addiction Severity Index, Conners adult ADHD Rating Scales Self-Report (CAARS-S:L), and the Kiddie-Sads-Present and Lifetime Version (K-SADS-PL).

Results

Using CAARS-S:L, the ADHD index showed that 9 subjects (17.6%) were diagnosed with adult ADHD. Using K-SADS-PL, 8 of the participants (15.7%) were found to have an adult ADHD diagnosis. Lower scores of the ADHD index are related to increased patients’ age, while increased scores of the ADHD index are related to more alcohol-related problems of the patients. The strongest predicting factors of increased ADHD index were drug problems and legal status.

Conclusions

The current study provides evidence of an increased diagnosis of adult ADHD in patients with substance use disorder, regardless of the type of substance abuse.
Parasitic limb excision in a neonate: a rare occurrence
Authors: Habib Murad , Chaudhary Muhammad Amjad
Published: September 2022

Background

Parasitic limb is a rare congenital anomaly. Its incidence is less than 1 in 1 million live births. It refers to the type of conjoined twin in which tissues of an incompletely formed twin (parasite) are attached to and dependent upon a fully developed twin. Since it is a rare anomaly, all the cases should be reported.

Case presentation

This study reports a 3-day-old neonate admitted to the Children's Hospital Emergency. Her initial complaints were an extra limb arising from her lower back. She was born as a result of cousin marriage and was not diagnosed antenatally. The limb was attached to the lower lumbar region (L4, L5, S1). The limb was hypoplastic, and the baby was unable to hold it against the gravity but she cried when it was pinched suggesting pain sensations. Preoperative diagnostic workup was done, and parasitic limb was excised.

Conclusion

Every child with parasitic limb is a surgical dilemma. Thus, a multi-disciplinary approach and a carefully planned surgery with meticulous dissection can result in complete excision of a parasitic limb without any complications.
A Software-Guided Approach to Hemodynamic Management in a Renal Transplant Recipient: A Case Report
Authors: Woodford Stephen F. , Miles Lachlan F. , Lee Dong-Kyu , Weinberg Laurence
Published: September 2022

The function of renal allografts in the perioperative period is partly dependent on minimizing hemodynamic instability. We have developed hemodynamic monitoring software—named the “pressure field”—that was utilized in a 68-year-old high-risk kidney transplant recipient. The “pressure field” was used to individualize fluid and drug administration and replicate the preoperative hemodynamics. The patient received net zero fluid intraoperatively and had an uneventful postoperative course. We found the pressure field method helpful to manage perioperative hemodynamics in this high-risk patient.
Dehiscence and Deep Wound Infection After Spinal Cord Stimulator Implant Managed Without Explantation: A Case Report
Authors: Wang Hank C. , Auyeung Andrew , Aijaz Tabish , Candido Kenneth D. , Knezevic Nebojsa Nick
Published: September 2022

Deep infections of spinal cord stimulator devices usually result in explantation, as recommended by some professional societies. However, alternative options should be explored to avoid potential complications that are associated with explantation, and possibly additional procedures required in consideration of reimplantation. In this case, the patient presented with wound dehiscence after implantation. There was suspicion for deep wound infection based on a wound culture that was positive for Staphylococcus aureus, but no purulent material was noted on further inspection. The patient was treated with standard wound-care management and oral antibiotics without removing the device, and recovered while preserving the original system.
A novel framework for online decision-making and feedback optimization of complex products process parameter based on edge-cloud collaboration
Authors: han chong , zhou guanghui , zhang chao , yu yongrui , ma dongxu
Published: September 2022

Background: Intelligent manufacturing is perceived as a manufacturing mode with powerful learning and cognitive capabilities empowered by information technologies such as the internet of things, edge computing, and cloud computing. The mode can be used to address the problems of low intelligence and poor timeliness of traditional process planning.

Methods: The framework includes the multi-objective process planning method based on real-time data, and the process closed-loop optimization mechanism of “cloud-based theoretical process planning plus edge MEC (multi-access edge computing) side online simulation verification and real-time feedback adjustment”, which realizes online process planning and iterative optimization in mass customization.

Results: The feasibility of the online analysis method for thin-walled part milling deformation is verified by taking the finishing process of aerospace thin-walled parts as an example. The experimental results show that the simulation time on the single analysis step is reduced from 6s to 1s, and the accuracy rate is 86.9%.

Conclusions: A new intelligent process planning theoretical framework integrating with online process planning and autonomous collaborative control, namely, digital twin and multi-access edge computing process planning (DT-MEC-PP) is proposed in this paper.
Intra-abdominal hypertension during hip arthroscopy: a case report
Authors: Kim Saeyoung , Ri Hyun-Su , Kim Ji Hyun , Yeom Jiyong
Published: September 2022

Symptomatic extravasation of irrigation fluid is a rare complication of hip arthroscopy. However, depending on the amount of fluid, intra-abdominal hypertension (IAH) may occur and even develop into abdominal compartment syndrome, which can seriously alter hemodynamic circulation. Therefore, it is important for anesthesiologists to promptly recognize the abnormal signs of IAH for early diagnosis and better clinical outcomes. Nevertheless, these signs are difficult to detect because they are usually obscured when the patient is under anesthesia and masked by surgical drapes. We report a case of IAH under general anesthesia during hip arthroscopy to highlight possible symptoms and signs.
Invited Commentary—“How Support for Black Lives Matter Impacts Consumer Responses on Social Media”
Authors: Thomas Jacquelyn S. , Chintagunta Pradeep K.
Published: September 2022

In this commentary of “How Support for Black Lives Matter Impacts Consumer Responses on Social Media,” we discuss issues related to the research approach, findings, and offer suggestions for future research.
What Makes Agility Fragile? A Dynamic Theory of Organizational Rigidity
Authors: Li Jin , Mukherjee Arijit , Vasconcelos Luis
Published: September 2022

We present a novel explanation of why organizations tend to lose their agility over time despite their efforts to foster worker initiative in adapting to local information. Worker initiative ensures efficiency but requires strong incentives. When incentives are relational and the firm faces shocks to its credibility, it may adopt standardized work processes that ignore local information but yield satisfactory (though suboptimal) performance. The adoption of such standardized processes helps the firm survive the current shock but inflicts inefficiencies in the future. Although the firm may recover, it becomes more vulnerable to future shocks, and consequently, more reliant on the standardized work procedures.

This paper was accepted by Joshua Gans, business strategy.
Disentangling Reputational Effects in Alliances
Authors: Costa Afonso Almeida , Costa Luís Almeida , Vasconcelos Luís
Published: September 2022

An important consequence of an alliance is that partnering firms combine their reputations by associating them to jointly implemented projects. However, an often-overlooked aspect is that those reputations may themselves change due to both the announcement of the firms’ decision to form the alliance and the performance of joint projects. We develop a formal model that provides an integrated perspective of these reputational effects, while allowing us to isolate and characterize each of them. We find that the way in which the firms’ competence levels affect their decision to form an alliance determines how the firms’ reputations evolve following the announcement of the alliance and the performance of joint projects. This indicates that the analysis of the reputational effects of an alliance requires understanding the firms’ alliance formation decision in the first place. We show, for instance, that a firm’s reputation may decrease following the decision to form an alliance, and that the impact of project performance on the reputations of alliance partners can be very asymmetric. Among other things, our analysis implies that a firm’s desirability as an alliance partner does not necessarily increase with its reputation and level of competence.

Funding: A. Almeida Costa and L. Almeida Costa thankfully acknowledge funding from the Fundação para a Ciência e a Tecnologia [Grants UID/ECO/00124/2019, UIDB/00124/2020, UIDP/00124/2020, and Social Sciences DataLab–PINFRA/22209/2016], as well as from POR Lisboa and POR Norte [Social Sciences DataLab–PINFRA/22209/2016].

Supplemental Material: The e-companion is available at https://doi.org/10.1287/stsc.2022.0175 .
EDUCAÇÕES EM TEMPOS DE CIBERCULTURA
Authors: Carvalho Felipe , Santos Edmea , Pimentel Mariano , Santos Rosemary dos
Published: September 2022

Nesta presente 17º Edição, v. 6, n. 3,  publicamos o número temático organizado por Prof. Dr. Carloney Alves de Oliveira (UFAL): “EDUCAÇÃO MATEMÁTICA E CIBERCULTURA EM CONTEXTOS DE ENSINO E DE APRENDIZAGEM”.
Vulnerabilidade individual, social e programática na adesão ao tratamento antirretroviral em adultos
Authors: Miranda Mariana De Morais Fortunato , Oliveira Dayanne Rakelly de , Quirino Glauberto Da Silva , Oliveira Célida Juliana de , Pereira Maria Lúcia Duarte , Cavalcante Edilma Gomes Rocha
Published: September 2022

Objetivo: analisar a associação da adesão à terapia antirretroviral em adultos com HIV/Aids e as dimensões das vulnerabilidades. Métodos: estudo quantitativo, com 230 pacientes de serviço especializado, por meio de questionários de avaliação da adesão ao tratamento, com dados submetidos à análise estatística inferencial. Resultados: dos pacientes, 44,3% apresentaram boa/adequada adesão com elementos da vulnerabilidade individual: apoio para conversar/desabafar sobre o problema de saúde (p=0,002); apoio para se divertir ou fazer atividade de lazer (p=0,000); e deixar de tomar a medicação devido à alteração na prescrição médica (p=0,018); social: sexo (p=0,005); nível de instrução (p=0,010); renda familiar (p=0,034); e condição empregatícia (p=0,007); e programática: acesso ao serviço (p=0,005); recebimento de informações (p=0,039); comunicação com os profissionais (p=0,024); educação em saúde (p=0,013); e deixar de tomar a medicação por não tê-la (p=0,039). Conclusão: a adesão foi classificada como boa/adequada e apontam-se elementos de vulnerabilidades que fragilizam ou potencializam a adesão.
Risco de violência e qualidade de vida de pessoas idosas atendidas no ambiente hospitalar
Authors: Cunha Hurana Ketile da , Brandão Bárbara Maria Lopes da Silva , Soares Jefferson Da Silva , Araújo Ângela Amorim de , Dantas Rodrigo Assis Neves , Souto Rafaella Queiroga
Published: September 2022

Objetivo: analisar a associação entre o risco de violência e a qualidade de vida de pessoas idosas no ambiente hospitalar. Método: estudo quantitativo, transversal, multicêntrico, desenvolvido com 323 pacientes atendidos em dois hospitais universitários da Paraíba. Foram utilizados instrumentos de caracterização sociodemográfica, risco de violência e qualidade de vida. Os dados foram analisados por estatística descritiva e inferencial, mediante o teste de qui-quadrado de Pearson, correlação de Spearman e regressão logística múltipla. Resultados: o risco de violência foi prevalente em mulheres idosas e com baixa qualidade de vida. As pessoas idosas com baixa qualidade de vida apresentaram 5,24 (IC = 3,04 - 9,05; p < 0,001) maior probabilidade de apresentar risco de violência. Conclusão: foi identificada associação significativa sob o ponto de vista estatístico entre a qualidade de vida e o risco para a violência entre pessoas idosas.
Adaptação transcultural e validade de conteúdo do Multidimensional Fatigue Inventory–10 para o português do Brasil
Authors: Andrade Rodrigo De Oliveira , Luiz Franciane Silva , Almeida Geovana Brandão Santana , Leite Isabel Cristina Gonçalves , Coelho Angélica Da Conceição Oliveira , Carbogim Fábio Da Costa
Published: September 2022

Objetivo: descrever o processo de adaptação transcultural do Multidimensional Fatigue Inventory-10 para paciente em tratamento oncológico, no contexto brasileiro e avaliar suas evidências de validade de conteúdo. Método: estudo psicométrico, com aplicação de protocolo caracterizado por cinco etapas para adaptação transcultural, incluindo tradução inicial, síntese das traduções, retrotradução, comitê de especialistas e pré-teste. As evidências de validade de conteúdo foram analisadas por meio do Content Validity Ratio. Resultados: o instrumento foi traduzido e adaptado de forma cultural, mantendo-se as equivalências semântica, idiomática, experimental e conceitual. A análise das equivalências entre os juízes resultou numa taxa de concordância superior a 80%. A versão final obteve coeficiente de validade de conteúdo de 0,94, com variação entre 0,87 e 1,0 para os itens. Conclusão: a adaptação cultural do Multidimensional Fatigue Inventory-10 para o português do Brasil permitiu a adequação do instrumento ao contexto brasileiro, com aplicabilidade aos pacientes oncológicos.
O fim anunciado da Rede Cegonha – que decisões tomaremos para o nosso futuro?
Authors: Zveiter Marcele , Mouta Ricardo José Oliveira , Medina Edymara Tatagiba , Almeida Luciane Pereira de , Silva Sandra Cristina De Souza Borges , Martins Elaine Lutz
Published: September 2022

Objetivo: contextualizar as mudanças anunciadas para as políticas públicas de saúde, incluindo a Rede Cegonha, como momento histórico decisivo para o futuro da Enfermagem no Brasil, e para a garantia de direitos das mulheres e seus filhos. Conteúdo: O percurso histórico e político das lutas da Associação Brasileira de Obstetrizes e Enfermeiros Obstetras, amparado pela legislação e marcos regulatórios da Enfermagem brasileira e das Políticas Públicas de Saúde da Mulher, enfatiza a importância do papel das Enfermeiras Obstétricas como sujeitos políticos, para a tomada de decisões frente ao futuro da Enfermagem. Porém, apesar dos avanços na mudança de modelo de assistência obstétrica e neonatal por meio da Rede Cegonha, a implementação da Rede de Atenção Materna e Infantil ameaça tanto a atuação da Enfermagem Obstétrica como a garantia dos direitos humanos das mulheres. Considerações finais: O desmonte da Rede Cegonha intensificada os desafios e exige decisões para o futuro da Enfermagem.
GESTÃO MUNICIPAL DOS RESÍDUOS SÓLIDOS URBANOS EM SÃO GONÇALO, RJ: DESAFIOS E LACUNAS
Authors: Da Silva dos Santos Jorge Edmir , Henriques Pereira van Elk Ana Ghislane , Ferreira João Alberto
Published: September 2022

O trabalho versa sobre os desafios encontrados pelas administrações municipais para implementar às diretrizes preconizadas pela Política Nacional de Resíduos Sólidos (PNRS), Lei 12.305/2010. Quase 10 anos após a aprovação da Política Nacional os desafios observados consistem em verdadeiros entraves, limitando, por vezes, as ações dos municípios à coleta e a destinação final ambientalmente adequada dos resíduos sólidos em aterros sanitários e ao encerramento dos lixões existentes. O presente estudo de caso foi realizado em São Gonçalo, município localizado na Região Metropolitana do Rio de Janeiro. Possui uma população superior a um milhão de habitantes e, de acordo com o Plano Estadual de Resíduos Sólidos apresenta uma geração per capta de resíduos sólidos de 1.11 kg/hab/dia, o que o faz ocupar a quinta colocação entre os maiores geradores do Estado do Rio de Janeiro. Observou-se que o sistema de limpeza urbana é operado em elevado déficit financeiro, devido à baixa arrecadação com a taxa de coleta de lixo domiciliar, e que a ausência de um órgão centralizador na administração pública municipal tem sido um fator determinante no planejamento de uma gestão que atenda minimamente aos instrumentos propostos pela Política Nacional de Resíduos Sólidos como criação de programas de educação ambiental, desenvolvimento de políticas públicas para a inclusão de catadores, realização da coleta seletiva, implementação do Plano Municipal de Gestão Integrada de Resíduos Sólidos e a análise da viabilidade de consórcio público.
Ways of formation of metaphors in the literary text as realization of the maintenance of nominations of gestures (on the material of the work “Atonement” by I. McEwen)
Authors:   Municipal Institution of Higher Education ", Melnychuk Oksana ,   Rivne Medical Academy", Hrytsiv Nataliia ,   Lviv Polytechnic National University
Published: September 2022

This paper presents a study of ways to form metaphors to realise the content of nominations of nonverbal elements – gestures – identified in modern British prose – the novel “Atonement” by I. McEwan. Analysing textual contexts made it possible to single out the types of metaphors in the literary text. These metaphors are united by a standard metaphorical transfer of a non-verbal element-gesture. It is emphasised that words are “containers” of meanings, and the perception of speech is the coding of pre-existing meaning, and its understanding is decoding. It is pointed out that messages are containers filled with values that are sent from a sender to a recipient. In general, conceptualising linguistic communication according to the model of fixed (written) text, we understand linguistic communication in terms of the difference between language (as an existing system) and its implementation (as a written literary text). It was found that from the reader’s point of view, it is crucial to know the meaning of non-verbal elements-gestures, which are the basis for their rethinking in the context of metaphor in the literary text. These structures help readers develop the meaning of the literary text, going beyond explanations of gestures in terms of psychological functioning and metaphorical meaning.
The problem of English communicative clichés classification
Authors:   State Institution Luhansk Taras Shevchenko National University, Koknova Tetiana
Published: September 2022

Regular combinations of verbal units, which are defined as autonomous linguistic formations with a given traditional meaning and form, i.e., language clichés, attract particular scientific interest in the process of communication. The author considers the nature of the concept of language clichés, and the laws of their existence in English in Ukrainian and foreign scholars’ viewpoints. The researcher believes that the issue of classification of English communicative clichés is still relevant. The study aims to analyze and compare existing classifications of English clichés. In the course of the research different approaches to the classification of English clichés on a situational basis are considered and analyzed. It is established that the most common are those classes that are distinguished by the majority of the researchers (clichéd appeals, cliché to attract attention, cliché-farewell, cliché-acquaintance, cliché-congratulation, cliché-request, cliché-gratitude, cliché-apology, cliché of agreement or disagreements, clichés to express position, clichés of approval and disapproval, clichés of consolation, clichés of compassion, clichés of advice). Conversational formulas for the meeting appointment and formulas of expression of indifference are singled out. The classification of colloquial clichés given by Martin Hunt is also considered. The classification given by R. Delevska is analyzed in detail. It is based on thematic and functional features, due to which the classification becomes more generalizing. Language clichés are divided into informative, motivational, evaluative-modal, contact, and metacommunicative ones. As a result of the study it is concluded that the considered classifications are reasonable and practically used in describing the arrangement of language clichés in English. It is also noted some shortcomings related to the thematic aspect of clichés, which is due to the difficulty of distinguishing certain language situations. Analysis of these classifications shows that there is no consensus among researchers of English clichés on the allocation of classes based on situational characteristics, as selected by one linguist classes of language clichés are controversial to cliché classes identified by other researchers.
To the comparable characteristics of folk and literary floristic names in the Ukrainian language
Authors:   Institute for Ukrainian Language of the NAS of Ukraine, Poistohova Maryna
Published: September 2022

Literary and dialect languages influence each other and, as a result, mutual enrichment occurs, in particular in botanical vocabulary. Comparison of folk and literary floristic names in the Ukrainian language reveals: common names for literary language and dialects (with phonetic, word-formative, semantic variants in dialects); common names with different lexical meanings; many words with a broader semantic structure in dialects; figurative meaning of words in dialects; the existence of different lexemes to describe the same object in floristics; numerous names in dialects are represented by synonymous pairs; the influence of the literary language on dialects, and as a result formation of duplicates (lexical, word-forming, phonetic); dialect words and meanings that are part of the literary-normative ones; specific dialect words not used in the literary language; words known only to older people which, even in the speech of representatives of the older generation, have moved to passive vocabulary; names that are represented by a word in a literary language, but in dialects – by a phrase or even descriptively. Dialect names reveal greater lexical, phonetic, word-forming, semantic variability. The mutual influence of the literary language and dialects contributes to the improvement of the norms of the literary language, and appears to be the basis for the development of the national language.
Peculiarities of conveying the content of english headlines into the Ukrainian taking into account the addressability of the text (based on the material of episodes of TV series)
Authors:   Higher Educational Institution of Ukoopspilka ", Ishchenko Valentyna ,   Poltava University of Economics and Trade", Horbunova Sofia ,   Higher Educational Institution of Ukoopspilka "Poltava University of Economics and Trade"
Published: September 2022

The article substantiates that the current problems related to the translation of texts of various styles from English into Ukrainian, the problem of adequately transferring the content of English titles into Ukrainian, taking into account the characteristics of the target audience, are especially important. The material of the study was the titles of episodes of two modern television series, “Supernatural” and “Bob’s Burgers”, which were analyzed from the point of view of their perception by potential recipients. The main methods of research were: translational and comparative, contextological, elements of quantitative analysis. In the process of analysis, we singled out the following categories to which the links and references present in both projects can be attributed: 1) in-universe (the name of the episode is based on a character, plot, place or situation in the series itself); 2) references to a book, film, TV show or musical composition; 3) references to religious texts, use of fixed expressions, idioms, proverbs, etc.; 4) the use of fixed expressions, idioms, proverbs, etc.; 5) references to everyday, historical, geographical realities and personalities. The results of the analysis show that the translation of headline texts from English into Ukrainian is influenced by the addressee factor. The specifics of the addressability of the studied texts means taking into account the social and psychological characteristics of the intended recipient.