bluuebunny/crossref_metadata_2025 huggingface dataset:
IPTEKS PENGAWASAN TERHADAP REALISASI ANGGARAN DENGAN KONSEP GOOD GOVERNANCE DALAM MENCEGAH PRAKTEK KORUPSI DI DINAS PEKERJAAN UMUM DAN PENATAAN RUANG DAERAH PROVINSI SULAWESI UTARA
Authors: Tombokan Andre Feral Adolf , Pangerapan Sonny
Published: June 2019

Indonesia’s development depends on managing the budget state revenues and expenditures (APBN) therefore the government must be aware and change his character not to work alone without paying attention the interest or aspirations of the community. The purpose of this research is to know the flow or budget process at the public works agency and spatial planning in north Sulawesi province know the concept of good governance in carrying out supervision of realization budget, and to find out good governance in an effort to prevent corruption practices .this research is a qualitative research approach interpretive . the source of data from this study is primary data in the form of direct interviews, documentation and recording. Technique processing and analysis of data, namely the method of comparison by finding answers fundamental answers to cause and effect by analyzing factors the cause of the occurrence or emergence of a particular phenomenon. The result of this study indicate that the flow and budget process is on the PUPRD office in north Sulawesi, the budget planning process starts from conducting infestation field survey, after conducting surveys and data needed has been fulfilled, the budget calculation is carried out after it is entered planned DPA (budget implementation document) budget activities, after the DPA is published, we switch the process of physical implementation of work, including planning, design and so on,the concept of good governance in doing supervision of government budget realization is responsible for optimize the relationship between input and output. For example, for example public works agency, its input in the form of a budget can still be seen in its performance. Control,focused on how to utilize input minimum to produce the desired output that is in accordance with provisions and quality standards set at the time and quantity as which are desired. Keywords : supervision of budget realization
IPTEKS AKUNTANSI SUMBER DAYA MANUSIA PADA PENCAPAIAN TARGET CONSUMER LOAN
Authors: Johannes Christy Handayanie , Kindangen Wulan D.
Published: June 2019

Human Resources are important assets, Accounting for human resources Human Resource Accounting is an acknowledgment that people constitute human capital and human assets. The economic theory of human capital is based on the concept that humans have the skills, experience, and knowledge which are forms of capital, which are called "human capital managementthat must be owned in the world of work. Although now the world is getting more sophisticated but if there is no Human intervention, of course the machine will not work well. As in the world of work the Consumer Loan Area Of Manado of course, is in desperate need of Human Resources, in achieving  loan credit. Consumer Loan Area Manado customers must maintain and balance the development of local Human Resources. To reach the target, of course, the Consumer Loan has its own way of empolying Human Resources called sales. Sales work to product sales and must understand marketing management in Consumer Loansfor example, collaterals from each registered developer. And sales gave developers an offer so that developers would also want to join the Bank Mandiri Consumer Loan In Manado. However, the sales must also obey and understand the regulations in the Consumer Loan.and if Human Resources work well in the company where they work. Then each gets a profit, for example. Sales get a lucrative bonus from the company because it has helped to achieve the target of Home Ownership Loans. And the company also received a plus because it achieved satisfactory results.and applying good principles and governance with good corporate governanceKeywords: human capital management, local human resource development,marketing   management
IPTEKS EVALUASI PEMBINAAN DAN PENGAWASAN PENYELENGGARAAN PEMERINTAHAN DAERAH PADA DINAS TENAGA KERJA DAN TRANSMIGRASI DAERAH PROVINSI SULAWESI UTARA
Authors: Mawuntu Nikita Srisilia , Maradesa Djeini
Published: June 2019

Good governance is a requirement in every regional and central government. To ensure the good governance has proceeded well in the unity of government, then a regulation about guidance and supervision of the regional government is arranged which regulates all about the implementation of guidance and supervision in the regional government. The Official of Manpower and Transmigration of North Sulawesi Province is one of the official agencies that has a large workload and has implemented the internal guidance and supervision in accordance with applicable regulations. This was assessed based on the Regulation of Republic of Indonesia’s Government No. 12 of 2017 concerning the Guidance and Supervision of the Implementation of Regional Government. And in order to support the realization of a good government system in the North Sulawesi Province, the Department of Manpower and Transmigration continues to strive to maintain the process that has been carried out.Keywords: good governance, guidance, supervision, regional government
IPTEKS KETEPATWAKTUAN DAN KETERANDALAN PELAPORAN KEUANGAN DITINJAU DARI PENGENDALIAN INTERNAL PADA BADAN KEUANGAN DAERAH KOTA TOMOHON
Authors: Langkedeng Don Juan Jacobs , Saerang David P. E.
Published: June 2019

Accounting information systems and controls adequate internal can provide complete conclusions from a information conditions in the government to be used as accounting information for determine accuracy input data to output to be used government decision making. The research is entitled Effect of Technology Information and Understanding of Auditors on Internal Control of the Process Information System Audit (Survey on BKD Tomohon City). Purpose of research form knowing the effect of information technology on the information system audit process , m know the influence of the auditor's understanding of internal control over information system audit process and form know the influence of information technology, the auditor's management of internal control of the system audit process information on the Tomohon City Regional Finance Agency. Method research uses explanatory methods with data collection techniques through observation, questionnaire. Research results shows that information technology at the Agency Regional Finance of Tomohon City has a strong and significant to the audit process it information system. Technology information can help and facilitate the auditor in carrying out the system audit process information. The auditor's understanding of internal control of the Agency Regional Finance of Tomohon City has a moderate and significant relationship with the information system audit process. The information system audit process is running well and produce a good report if the auditor is capable understand the internal control system well, especially control internal with the presence of computerization. Information Technology and control internal has a strong and significant influence on the audit process information at the Regional Finance Agency of Tomohon City. Use of technology better information and auditor understanding of internal controllable to improve and facilitate the information system audit process. Information technology improvement auditor's assessment and assessment of internal controllable to improve the information system audit process even better. Decline information technology and understanding of capable internal controls reduce the efficiency and effectiveness of the information system audit process information.Keywords: Internal Informasion On The Timelty And Reability Of Financial Reporting
IPTEKS PENGENDALIAN INTERN TERHADAP ASET TETAP DI KANTOR PENGAWASAN DAN PELAYANAN BEA DAN CUKAI TIPE MADYA PABEAN C / KPPBC TMP C BITUNG
Authors: Mamentu Timons P. M. , Budiarso Novi S.
Published: June 2019

This article discusses about the implementation of IPTEKS of internal control on fixed assets. The method used in this article is how to implement the internal control structure. In order to implement the internal control well, an organization must fulfil the 5 aspect in internal control, which are: environment control, risk grading, information and communication, supervision, and activity control. It is suggested that Office of Customs and Excise Branch Bitung to keep maintaining the applied internal control..Keywords: internal control, service, fixed assets
IPTEKS EFEKTIVITAS PENGOLAHAN DATA WAJIB PAJAK DENGAN APLIKASI PADA KANTOR PELAYANAN PAJAK PRATAMA MANADO
Authors: Mandagi Jaquline , Wangkar Anekke
Published: June 2019

Tax has great benefits for the development of the Indonesian nation. This is because taxes are the biggest potential revenue in the country. Because taxes are direct receipts that can be processed to finance various kinds of state needs. Seeing the rapid development of technology, the Directorate General of Taxes (DGT) uses technology as an alternative channel of communication with tax payers. Therefore the Pratama Tax Office Manado relies heavily on Digital Technology in the form of electronic media and social media to facilitate processing of taxpayer data. The purpose of this study is to find out the effective processing of data with applications (software) under the supervision of the Directorate General of Tax Information System in collecting taxpayers at the Manado tax service office. Electronic media can be used to disseminate information relating to socialization, counseling and as a means of communication to the WP used by the DGT through socialization, letters, e-mail, websites and call centers. With the use of technology can improve work effectiveness, save time, effort and thought, and accelerate the flow of information for leaders to make decisions.Keywords: effectiveness, tax, technology, application
IPTEKS PENGENDALIAN INTERN TERHADAP LELANG BARANG GADAI PADA PT. PEGADAIAN (PERSERO) CABANG KAROMBASAN
Authors: Lompang Muh. Rivaldi Dg , Kalalo Meily Y.B.
Published: June 2019

Pegadaian is one of the financial institutions owned by BUMN , where the main business is about credit something with the guarantee that the pawned tools move on the basis of financial law. This material can guarantee absolute rights to certain items of interest which are the object of guarantee of a debt and whenever it can be cashed for the payment of items that have been made in the agreement if it cannot complete the deals of payment. Auction is a sale of items for public place where the price are published in writing or directly, which increases or decreases in order to reach the highest price. The Auction is done if the customer is unable to fulfill his obligation to return or extend the mortgage item, and the Auction will be done in public place. PT. Pegadaian (Persero) has the right to sell the guarantee items belongs customers in an Auction. but before the Auction PT. Pegadaian (Persero) Karombasan Branch will confirm or remind the customer that the items in the pawn have out of date or have passed the payment limit. So the misunderstanding will not happen between the company and the customer.Keywords : procedure for auctioning goods pawned
IPTEKS PENERAPAN DAN MANFAAT TEKNOLOGI INFORMASI TERHADAP PROSES BISNIS PERBANKAN PADA PT. BANK RAKYAT INDONESIA (PERSERO) TBK. KANTOR CABANG MANADO
Authors: Anis Valencia Matthew , Tangkuman Steven J.
Published: June 2019

The use of information technology plays an important role in the company's business processes. One of the success factors of company performance is the optimal use or application of information technology. Especially in banking business process activities, the use of information technology is one of the weapons in competition in the banking business world. In this article Bank BRI, which is one of the largest banking companies in Indonesia, also relies on information technology in the continuity of its business processes. In this article, we will discuss about the application of the Bank BRI Manado branch office’s Information Technology and its benefits in the continuity of banking business processes. In this case the BRI bank Manado branch office uses a variety of information systems in the banking business processes that will be explained in this article.Keywords : Business Processes, Information Technology, Banking business, Information System, Bank
IPTEKS PERLAKUAN AKUNTANSI TERHADAP PENGUKURAN ASET TETAP PADA KANTOR LURAH KLEAK
Authors: Ipu Reinhard Valen , Pinatik Sherly
Published: June 2019

Fixed assets are tangible assets owned by the company or agency in question not for sale, but to assist the operational activities of an agency and have a useful life of more than one year. The kleak village office has several supporting factors in conducting operational activities, one of which in the form of office equipment. This study aims to determine wherher the village office has measured fixed assets based on applicable financial accounting standards. Based on the data that the author obtained it can seen that the village office has not measured fixed assets in accordance with PSAK No. 16.Keywords : Measurement of fixed assets, PSAK No. 16
IPTEKS PENGHITUNGAN RISIKO PASAR DALAM KEPUTUSAN INVESTASI
Authors: Pontoh Winston , Budiarso Novi Swandari
Published: June 2019

Well-established life is a common objective of people, and in term of to reach that objective then most of people should utilize knowledge and skills. One of the effort of people is normally make an investment especially stock investment. One of the reference for investors in case to make stock investments is market risk. Stock beta is one of market risk representative which measures stock responsiveness on market movements and capital asset pricing model (CAPM) is one method to measure market risk.Keywords : market risk, stock investment, CAPM
IPTEKS MENGUKUR NILAI PERUSAHAAN DI PASAR MODAL PADA PERUSAHAAN YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Sondakh Renly , Morasa Jenny
Published: June 2019

Investment is an investment activity to obtain a return on investment (return) that will be received in the future. In investing, investors should see whether the company that will buy the shares is good or not, so investors should analyze or measure the value of the company to buy shares by using price earnings ratio and price to book value so that investors know which company is good not. Through this research, it is explained how to measure the value of the company that will be bought in its shares. This study also aims to find out how to measure the value of the company to be purchased.Keywords: Firm value, Price Earnings Ratio, Price to Book Value
IPTEKS ESTIMASI BIAYA BAGI USAHA KECIL MENENGAH DALAM PERENCANAAN BIAYA
Authors: Budiarso Novi Swandari
Published: June 2019

Small and medium enterprise has been growing fast in Manado City and has its own markets and also create its competitive advantage. Most of government programs are reflect the effort to support small and medium enterprise in term to increase the wealth of Indonesian people. Some of problems faced by small and medium enterprise are relate to managerial problem, such as administration and financial reporting. Moreover, limited of knowledge about management technology for the owners of small and medium enterprise plays the role in case to take decision on running business. High-low method is one of managerial tool to make cost estimation which help the owners to make decision such as cost planning.  Keywords : small and medium enterprise, fixed cost, variable cost, high-low method
基于协同育人的高职“课程思政”工作模式研究——以机电一体化专业为例
Authors: 彭 清 , 张 慧
Published: June 2019

高职普遍缺少推动“协同育人”的有效机制，各教学单位、各学科之间缺乏协同与合作。在传统教学中，教师“重专业轻文化”，学生文化课程基础较差、对思政教育漠不关心，自我意识和叛逆心理突出，因此，高职学生思想政治教育很少形成优势互补的合力工作局面。本文拟以机电一体化专业为例，从梳理高职院校“课程思政”协同育人的现状，分析其成因为契入点，尝试探索基于协同育人的高职院校“课程思政”的工作模式，以期改善当前高职院校大学生思想政治教育的工作局面。
基于现代学徒制的课程体系建设研究
Authors: 沈 薇
Published: June 2019

随着当代社会科技的飞速发展,产业发展日新月异,企业对于人才的要求不断提升,这就对技术技能人才的培养提出了更高的要求,作为技术技能人才培养的主力军——高职院校,其人才培养的模式受到了极大的挑战,传统的课堂教学模式已经不能适应产业转型升级带来的对高技术技能人才日益提升的数量和质量要求。现代学徒制在此背景下成为解决技术技能人才培养问题的重要途径,本文对现代学徒制模式下的课程体系进行研究和探索,以期能给现代学徒制本土化课程体系建设提供些微可借鉴的经验。
高中地理教学本土化案例的开发与利用
Authors: 许 海荣 , 王 兴梅
Published: June 2019

在全球化和本土化相互交融发展的今天,新课程的教学方案应该多在国内进行完善发展,应该立足于本土化的全球化道路形式,用一种现实的态度来迎接和推动我国教学的前进,也不是完全的去反对之前原有的传统教程方案。我们要把研究的重点放在现实主义上,研究本土化的实质,然后来进行本土化的实现。地理教学本土化的研究方案是对教育本土化的精神寄托,是对教育全球化的发展指向,同时也是对我国新课程发展引导的表现,并且对我国新课程的改革作为前进方向。在叙述本文的过程中从全球化与本土化的发展、教育本土化的发展、我国进行新课程改革这三个方向来进行从地理方面本土化的背景和意义指向,以地理教学本土化思想与内容的研究奠定良好的基础。从地理教学本土化教育基础来进行分析,在这个基础上来进行了解地理教学本土化的方面。具体会以教学方法中的案例教育为例,来分析在中学时地理教学的案例特征。
代币制激发学生自信的分析研究
Authors: 梅 海江
Published: June 2019

中职班主任借助“班级币”这一代币制手段,基于全人教育的理念,严格执行“斯金纳的操作性条件反射”原理,通过集体层面、学习技能、师生点赞、发放仪式、礼品代换、任务认领等六个角度强化,使学生全方位重新认识自己,树立自信。“班级币”管理模式,改变了学生的认知模式,激发了学生对自己负责的自发性,并且与社会融通具有很现实的社会性。
网络红人现象对大学生价值观的影响研究
Authors: 韩 伟
Published: June 2019

本文以网络社会背景下的网络红人现象为研究对象,通过对网络红人现象的解析,探究了网络红人现象对大学生价值观的影响,并结合辅导员工作实际,从法律引导、教育的视角,就网络红人现象影响下的大学生价值观教育对策进行了详细的介绍。
优质校建设视域下公共基础课开展素质教育的问题及对策研究
Authors: 鄢 彬
Published: June 2019

针对公共基础课在优质校建设过程中的定位和作用,如何开展素质教育,提高人才培养质量,都应重新审视。为此应当聚力服务专业人才培养目标和要求,提升社会服务能力；聚力身体素质提升,构建校园体育文化长效机制；聚力教学团队建设,激发师德师风内在动力；聚力课堂教学改革,提高教学的有效性。
技能竞赛成果在实际教学中的应用
Authors: 郝 晓飞 , 姚 辉
Published: June 2019

每年一次的职业院校技能竞赛是对教学成果的阅兵,是促进校企合作桥梁。本文通过对职业院校技能竞赛的理性思考,探析了职业技能竞赛对我们职业教学的意义,反思了职业院校技能竞赛成果对实际教学的促进。
Research on the influence of English teaching behavior based on association rules algorithm
Authors: 肖 菲
Published: June 2019

With the development of economic globalization, Chinese enterprises play an important role in the wave of global economy and their participation is deeper and deeper. It also brings a lot of troubles in communication. The demand for English talents is increasing, which requires our educational institutions to adjust the content of the teaching in a timely manner according to the market situation, especially in the case of a shortage of skilled personnel. Through the study of the influence of the English teaching behavior based on the association rules algorithm, this paper discussed how to carry out the teaching of English application more efficiently.
浅谈课堂中音乐游戏的指导策略
Authors: 陈 舒舒
Published: June 2019

音乐游戏是在音乐伴随下进行的,以发展儿童音乐能力为目标的一种有规则的游戏活动,它通过音乐与游戏的有机结合,使教育活动既具音乐方面的艺术性,也有游戏活动的趣味性。它是小学教育的重要组成部分,对于发展小学生的表达能力、创造力具有重要作用。音乐游戏不仅能有效地激发小学生的学习热情和兴趣,还能在加强师生以及同学之间沟通和交流的同时,促进培养小学生的创造力以及想象力。因此,研究音乐游戏的重要性及游戏中教师的指导策略对于小学的教育具有重要意义。
拓展训练对大学生心理的影响及实施策略
Authors: 李 程玉
Published: June 2019

现代社会的高速发展以及快速变革,使得人们的社会压力与日俱增。高校大学生不仅需要面临择业就业的巨大压力,还需要面对学业、人际交往以及经济等现实问题。为更好地适应社会发展,提高大学生心理素质已经成为高等教育人才培养的重要方向和主要内容之一。在高校素质教育改革深入推进的背景下,拓展训练成为解决大学生心理问题以及提高心理素质的重要平台。本文首先论述了该课题涉及的相关概念内容,然后就拓展训练对大学生心理的影响进行了细化分析,最后从拓展训练应纳入课程体系、拓展训练活动推广等方面给出了建议。
浅议案例解析与建筑学专业课程教学的关系——以《建筑设计1》和《公共建筑设计原理》为例
Authors: 朱 昊东
Published: June 2019

本文分析了《建筑设计1》和《公共建筑设计原理》的课程特点,以及建筑案例解析对两门课程的重要性。同时分别从“环境”、“形式”、“空间”三个维度介绍了解析与学习建筑案例的方法。
素质拓展对高职院校大学生人际关系影响研究
Authors: 刘 娟
Published: June 2019

“互联网＋信息”时代下,大学生人际关系面临着考验,不良的人际关系引发的心理问题也亟需解决。素质拓展训练成为当下改善大学生人际关系和心理健康水平的重要举措。本文在分析了高职院校大学生人际关系特点的基础上,探索了素质拓展对高职院校大学生人际关系的影响,并提出了有实践意义的对策,以期为高职院校大学生开展素质拓展实践活动提供理论依据。
培养高中学生语文口头表达能力的实践探索
Authors: 卢 慧芳
Published: June 2019

当今社会,口头表达能力与口语交际十分重要。口头表达能力是语言实践的重要工具,也是书面表达的基础。口头表达能力不仅能提高学生的学习效率,还可以为学生在以后的工作中奠定良好的基础。因此,在高中语文教学中教师应对学生的口头表达能力进行着重培养,探究学生口头表达能力的有效方法。本文通过对培养高中学生语文口头表达能力的措施进行探索,提出几点建议以供同行参考。
应用型本科院校学产对接实践教学平台构建的探索与实践——以吉林动画学院为例
Authors: 唐 莲
Published: June 2019

以学校转型发展为契机,探索“学研产一体,学用创相融”的应用型人才培养模式,构建校企合力育人的学产对接实践教学平台,实现专业之间交叉融合互动,推进科技创新成果转化,加快双师型师资队伍建设,建立培养高素质应用型人才的长效机制,对全面提升应用型人才培养质量,进一步推进校企合作及应用型大学建设具有重要意义。
音乐院校图书馆专家资料库馆藏建设探索
Authors: 郭 晶晶
Published: June 2019

本文以高校图书馆馆藏建设的规范与制度为依据,试图通过探讨专家资料库馆藏建设的途径,并从实践的角度去寻找如何更系统合理地建设专家资料库馆藏,从而为读者提供专业、准确的信息资源,切实做好深化馆藏服务与优化设计服务。
乡村中小学数学学科教研活动发展探究
Authors: 吴 红星 , 张 芬 , 骆 雯琦
Published: June 2019

随着我国新课程改革的深入,我国教研活动成为促进教师专业发展、学校发展和学生成才的重要途径,是搞好课程建设的有效保证,是提高中学教学质量的重要举措。最近,我们调查发现不少乡村中小学数学教师教研活动的工作状态不容乐观。本文从更新教师教学观念,提升教师教学素养,强化教师的教学与专业研究,建立健全评价与奖励制度等方面为我国乡村中小学教研活动发展提供建议与方案。
“现代学徒制”模式下高职酒店管理专业毕业设计实践
Authors: 谌 莲莲
Published: June 2019

毕业设计是高职院校人才培养方案中最后一个综合性教学环节,是对学生理论知识运用和技能掌握的有效评价。本文以近三年我校酒店管理专业毕业设计改革为例,在对现代学徒制模式下高职专业毕业设计实施现状进行分析,提出其存在的问题,结合实践探索,提出旅游类专业毕业设计体系优化思路。
Features of the enzyme composition of Jerusalem artichoke tubers
Authors: Bilenka I. , Lazarenko N. , Zolovska O. , Golinskaya Ya.
Published: June 2019

The article deals with different methods of preparing Jerusalem artichoke tubers to stabilize the color of semi-finished products and finished products. The varieties Interés and Violet de Rennes were chosen as objects of study. The purpose of this work is to study the activity of the enzyme system of Jerusalem artichoke tubers, followed by the use of raw materials as an ingredient in the preparation of culinary dishes with high nutritional and biological value. In accordance with the objective, the characteristics of the enzymatic composition of the material under study were researched. It was found that of the oxidoreductases present, the most active enzyme is polyphenol oxidase. It has been established that in the tubers of Jerusalem artichoke, the activity of polyphenol oxidase is in 1.8 times lower, peroxidase – in 1.34 times higher; ascorbate oxidase is in 2.79 times higher than that of Violet de Rennes tubers. A comparative analysis was performed on the reduction of the activity of enzymes and the preservation of the mass fraction of L-ascorbic acid in heat treatment and microwave processing. It has been established that the most successful method of treating Jerusalem artichoke tubers in order to inactivate the enzyme system and to preserve L-ascorbic acid is a microwave processing of 600 W in 1 minute. Studies have shown that with such preparation, the semi-finished product does not change color, the activity of the enzyme polyphenol oxidase decreases by 20 times, and the maintenance of the content of L-ascorbic acid is 68.4%. In further studies, it is important to study the technologies for preparing culinary dishes based on Jerusalem artichoke tubers using the results obtained to stabilize the color and preserve the biologically active substances of the raw materials.
The functional features of production of sour-milk product with gluten-free flour
Authors: Bolgova N. V.
Published: June 2019

The work substantiates the choice of leaven in order to produce a sour milk product with the most desirable organoleptic characteristics. As a result of the study, the fermentation for yoghurt of Chr. Hansen (Denmark) was selected. These studies determines the choice of scientifically proven methods of fermentation of the following samples. Organoleptic analysis of four samples of dairy products with gluten-free flour was carried out. It was shown that the consistency in each sample was homogeneous and estimated by the tasting commission at 5 points. It was established that the color and smell of samples of the dairy product directly depends on the type of introduced gluten free flour. It is shown that the color in the first and the third samples is estimated at 4 points. The second sample was slightly inferior and was estimated at 3.7 points. The highest score (4.8) was the fourth sample of buckwheat and rice-corn flour. The taste of pure sour milk was present in all abovementioned samples. It was found that the content of buckwheat flour in the first and the second samples gave the product an excessive taste of “porridge”. The taste of corn flour was distinguishedly felt in the third sample. It was shown that the first three samples yielded the optimum taste of the fourth to 0.6–1.9 points. It was found that the most balanced is the sour milk sample of the product with buckwheat and rice-corn flour. All organoleptic characteristics were distributed evenly in it. A new technological approach was developed in preparation of the milk-flour mixture to the fermentation. The model of technological process of manufacturing of sour milk product with gluten-free flour is made, which allows to develop technological stages of product production with functional additives. The influence of technological parameters and prescript components on the organoleptic parameters of the dairy product has been established. It was shown that the fermentation of the selected sample proceeds for 8 hours at a temperature of 43 ± 2 °С. The product is cooled to a temperature of 18 °C before aseptic packaging. It is recommended to store the ready gluten-free dairy product for 14 days at a temperature of 4–6 °C. Studies conducted show that the developed formula of sour-milk product can be recommended for the production of dairy enterprises.
An Energy-Efficient Elevator Operating System that Considers Sensor Information and Electricity Price Changes in Smart Green Buildings
Authors: Choi Hyunkyoung , Cho Kyungwoon , Bahn Hyokyung
Published: June 2019

In modern smart buildings, the energy consumption of a building is monitored every time. Smart buildings are also equipped with sensors that can collect various physical data such as temperature, motion, and light. In this paper, we use smart sensor technologies in the design of an efficient elevator operating system (EOS). Specifically, multiple sensor devices are used together to detect elevator passengers’ behavior before they arrive at the elevator door and press the elevator call button. The detected information is then delivered to EOS through building networks and the scheduling system utilizes this information for the efficient control of the elevator cars. Specifically, when the number of passengers becomes large, EOS increases the number of working elevator cars to reduce the waiting time of passengers. In contrast, when the elevator traffic lessens, EOS reduces the number of working elevator cars in order to save the energy consumption. Experimental results with a wide range of configurations show that our EOS outperforms the conventional elevator scheduling system that does not consider sensor information or electricity price changes.
Introduction of Local Spatial Constraints and Local Similarity Estimation in Possibilistic c-Means Algorithm for Remotely Sensed Imagery
Authors: Singh Abhishek , Kumar Anil
Published: June 2019

This paper presents a unique Possibilistic c-Means with constraints (PCM-S) with Adaptive Possibilistic Local Information c-Means (ADPLICM) in a supervised way by incorporating local information through local spatial constraints and local similarity measures in Possibilistic c-Means Algorithm. PCM-S with ADPLICM overcome the limitations of the known Possibilistic c-Means (PCM) and Possibilistic c-Means with constraints (PCM-S) algorithms. The major contribution of proposed algorithm to ensure the noise resistance in the presence of random salt & pepper noise. The effectiveness of proposed algorithm has been analysed on random “salt and pepper” noise added on original dataset and Root Mean Square Error (RMSE) has been calculated between original dataset and noisy dataset. It has been observed that PCM-S with ADPLICM is effective in minimizing noise during supervised classification by introducing local convolution.
Melatonin protects against cadmium-induced oxidative damage in different tissues of rat: a mechanistic insight
Authors: Mitra Elina , Bhattacharjee Bharati , Pal Palash Kumar , Ghosh Arnab Kumar , Mishra Sanatan , Chattopadhyay Aindrila , Bandyopadhyay Debasish
Published: June 2019

Cadmium (Cd) is a notorious environmental pollutant known for its wide range of toxicities to organisms. Thus, the present study is designed to examine whether melatonin, a potent antioxidant, protects against Cd-induced oxidative damage in the heart, liver and kidney of rats. Cd treatment at a dose of 0.44 mg/kg for 15 days caused severe damage in all these organs. These included significantly increased activities of SGPT, SGOT, lactate dehydrogenase- 1 and 5 and ALP and levels of total lactate, creatinine, lipid peroxidation, protein carbonyl content and reduced glutathione while the activities of superoxide dismutases, catalase, glutathione peroxidase, glutathione reductase and glutathione-S-transferase along with mitochondrial pyruvate dehydrogenase, isocitrate dehydrogenase, α-keto glutarate dehydrogenase, succinate dehydrogenase, NADH-cytochrome-c-oxidoreductase and cytochrome-c-oxidase were significantly reduced by Cd. However, if melatonin was given orally 30 min before Cd injection, all these alterations induced by Cd were significantly preserved by melatonin. Histological observations also demonstrated that Cd exposure caused cellular lesions, promoting necrotic or apoptotic changes. Notably, all these changes were significantly protected by melatonin. The results suggest that melatonin is a beneficial molecule to ameliorate Cd-induced oxidative damage in the heart, liver and kidney tissues of rats with its powerful antioxidant capacity, heavy metal chelating activity and competition of binding sites with Cd to the GSH and catalase.
Clinical uses of melatonin: evaluation of human trials on cancer treatment.
Authors: González González Alicia , Rueda Revilla Noemi , Sánchez-Barceló Emilio J,
Published: June 2019

Melatonin is a molecule with numerous properties, which are applicable to the treatment of different types of cancers. Experimental in vitro and in vivo studies conducted with human cancer cells or animal models of carcinogenesis, have shown that melatonin enhances apoptosis and inhibits cell proliferation of several human cancer cells, reduces tumor growth rate and its metastases, reduces the side effects of chemotherapy and radiotherapy, decreases the resistance to standard cancer treatments, and potentiates the therapeutic effects of other conventional therapies. These satisfactory results obtained from “bench” need to be studied in clinical trials to verify whether they are applicable to “bedside”. In this article we review the clinical trials carried out in the last 25 years which are focused on the therapeutic use of melatonin in cancer treatment. We conclude that melatonin is an effective adjuvant drug to practically any conventional cancer therapy since it is capable of improving the quality of life of patients, by normalizing sleep and alleviating general symptoms associated with tumor disease and treatment such as pain, asthenia, anorexia, etc. In the particular case of hormone-dependent breast cancer, melatonin's antiestrogenic properties make this indoleamine ideally suited for use in association with other synthetic anti-estrogen agents, as melatonin increases their efficacy while reducing their undesirable effects. Furthermore, melatonin could be an appropriate co-treatment for preventive treatment of breast cancer in people with elevated risk for this kind of neoplasia.
Mitochondria and the Gut as crucial hubs for the interactions of melatonin with sirtuins, inflammation, butyrate, tryptophan metabolites, and alpha 7 nicotinic receptor across a host of medical conditions.
Authors: Anderson George
Published: June 2019

Two important hubs have emerged as cutting edge areas of research across a diverse array of medical conditions, the gut microbiome and mitochondria. This article highlights the role of melatonin in modulating changes in both the gut and mitochondria. The gut microbiome, especially via its production of the small chain fatty acid, butyate, can have a significant impact on immune inflammatory processes. Lower levels of butyrate producing bacteria can increase gut permeability, thereby increasing immune-inflammatory activity. Butyrate may also modulate immune and other cells via the regulation of the content of exosomes from intestinal epithelial cells. Butyrate also induces N-acetylserotonin and melatonin synthesis in the gut, suggesting that some of the effects of butyrate may be mediated via its induction of the melatonergic pathway. The induction of melatonin by butyrate may feed back on the microbiome via melatonin increasing gut bacteria swarming, as well as melatonin optimizing gut barrier and mitochondria functioning. As butyrate readily crosses into the circulation it is likely that the immune- and glia-dampening effects of butyrate also involve the induction of melatonin in these reactive cells. Butyrate also positively modulates mitochondria functioning, suggesting that butyrate, both directly and via melatonin, will have significant impacts on gut, immune, glia and other cells, via mitochondria regulation. Other factors that act to regulate melatonin, including dietary factors and stress, will therefore act to modulate many of butyrate's effects. The regulation of melatonin at these two important hubs has significant treatment and classification implications across a wide array of medical conditions. Overall, gut dysbiosis has a significant impact on central and systemic homeostasis, via decreased butyrate and melatonin driving suboptimal mitochondria functioning. This has implications for the pathoetiology and pathophysiology of a host of medical conditions associated with gut dysbiosis and decreased melatonin production.
Melatonin down-regulates microRNA-10a and decreases invasion and migration of triple-negative breast cancer cells
Authors: Oliveira Jessica Gisleine de , Marques Jéssica Helena de Mora , Lacerda Jéssica Zani , Ferreira Lívia Carvalho , Coelho Marcelo Mafra Campos , Zuccari Debora Aparecida Pires de Campos
Published: June 2019

Breast cancer metastasis is one of the main factors associated with high mortality rates among patients. MicroRNAs (miRNAs) play an important role in gene expression regulation, and are associated with the metastatic process in breast cancer. Melatonin, a hormone secreted mainly in the pineal gland, has several oncostatic effects. The aim of this study was to investigate the action of melatonin in the modulation of miRNA-10a-5p and its association with metastatic mechanisms. We have evaluated the effects of melatonin on cell viability in MDA-MB-468 cell line after 24 hours of treatment. MDA-MB-468 and MDA-MB-231 cells were either transfected with inhibitor of miR-10a, or received a scrambled miRNA sequence as a negative control, then these cells were treated with or without melatonin. Gene expression of miR-10a was verified by real-time PCR. Invasion and migration assay using matrigel inserts were performed. The protein expression was analyzed by western blotting to quantify the epithelial-mesenchymal transition (EMT) markers (E-cadherin, claudin 7, and vimentin) and proliferation marker (PIK3CA). Our results showed that melatonin (1 mM) significantly decreased cell viability, and also affected miR-10a expression, which suppressed cell invasion and migration. Melatonin reduced vimentin and claudin 7 protein expressions, and increased E-cadherin. In contrast, inhibition of miR-10a reduced vimentin and did not modulate claudin 7 and E-cadherin. In conclusion, we demonstrated the effectiveness of melatonin in decreasing miR-10a, affecting invasion and migration, and proteins involved with the EMT process, which supports its potential role in the regulation of metastasis.
Cardioprotection and effects of melatonin administration on cardiac ischemia reperfusion: Insight from clinical studies.
Authors: Dominguez-Rodriguez Alberto , Abreu-Gonzalez Pedro , Chen Yundai
Published: June 2019

Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality. Many treatments have been identified that confer robust cardioprotection in experimental animal models of acute ischemia and reperfusion injury. However, translation of these cardioprotective therapies into the clinical setting of AMI for patient benefit has been disappointing. Many cardioprotective strategies act through common end-effectors and may be suboptimal in patients with comorbidities. Melatonin is a pleiotropic molecule with several functions. Its potential to protect the heart against ischemia/reperfusion damage has attracted much attention, particularly in view of its possible clinical applications. In this brief overview, we discuss the possible clinical application of melatonin in human.
Pleiotropic roles of melatonin against oxidative stress mediated tissue injury in the gastrointestinal tract: An overview
Authors: Pal Palash K , Bhattacharjee Bharati , Chattopadhyay Aindrila , Bandyopadhyay Debasish
Published: June 2019

The excessive production of free radicals and/or reactive oxygen species (ROS) in gastrointestinal (GI) tract leads to oxidative damages in GI tissues with development of varied pathological conditions and clinical symptoms. Many endogenous as well as exogenous factors are involved in such pathogenesis, herein, focus was given to the factors of metal toxicity, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion, consumption of high fat diet and alcohol, and different pathological conditions and diseases. Since ROS is more or less involved in the GI damages caused by these factors, therefore attempts have been made to develop appropriate therapeutic agents that possess antioxidant properties. Being a potent antioxidant and free radical scavenger, melatonin was suggested as a potent therapeutic answer to these GI damages. The discovery of different binding sites and receptors of melatonin in the GI tissues further proves its local actions to protect these tissues from oxidative stress.  In the review, we attempt to try our best to summarize the current developments regarding the GI injuries caused by oxidative stress and the potential beneficial effects of melatonin on these injuries. The important molecular mechanisms associated with these changes were also highlighted in the discussion. We hope that this review will provide valuable information to consider melatonin as a suitable molecule used for GI tract protection.
Membangun Jaringan Local Area Network Menggunakan Untangle 11.0 di Lembaga Quantum Padang
Authors: Rajab Rajab , Weafandi Anggie
Published: June 2019

The research raises issues relating to the Local Area Network (LAN) using Untangle 11.0. This research was conducted at Lembaga Quantum Padang. Based on the results of a survey conducted at Lembaga Quantum Padang, the authors found several problems including: data transmission, absence of teaching materials using a centralized computer network servers, and no implementation of bandwidth control and sites filtering. The results of this study are applied at the Lembaga Quantum Padang to facilitate data transmission and teaching materials, bandwidth control and sites filtering through a network of Local Area Network (LAN) using Untangle 11.0.
Aplikasi Pembelajaran Interaktif pada Mata Kuliah Maintenance pada Program Studi Teknik Informatika Sekolah Tinggi Teknologi Pagar Alam
Authors: Muslim Buhori , Putrawansyah Ferry
Published: June 2019

This study aims to produce interactive multimedia learning applications introduction of hardware and assembly of Personal Computer (PC) at Maintenance Course at Sekolah Tinggi Teknologi Pagar Alam and to improve learning the result. This research is based on the less interesting learning process, the interaction process is not running optimally and visualization is still using conventional media. Development method used is ADDIE that is Analysis, Design, Development, Implementation, and evalua-tion. Instruments used in the expert review to test the validity of the product and Pretest and posttest to measure student learning outcomes. Based on the results of the validity of the product got a score of 4.3 with the category is very valid then the pretest results conducted at the first meeting showed the average value achieved in the pretest is 66.77 with enough category. Then at the second meeting, after the learning process is implemented, held the post-test obtained an average of 90.56 with the category of Very Good. This shows an increase in learning the outcome of 24.31. In addition, obtained N-Gain of 0.732 which indicates that the learning process using multimedia applications that are made to improve student learning outcomes.
Sistem Pendukung Keputusan Pemilihan Sepeda Motor Bebek dengan Metode Elimination Et Choix Traduisant La Realite (Electre) Didukung Bahasa Pemrograman Java dan Database MYSQL
Authors: Sahari Sahari
Published: June 2019

Decision Support System (DSS) is a system that can assist a person in making accurate decisions and targeted. Many problems can be solved by using( DSS), one of which is the determination of election Motorcycles duck. There are several methods that can be used in building a (DSS) them (Electre). This study uses (Electre) in determining the election Motorcycles duck.In determining the Duck Motor bike, there are several criteria on which to base decisions, among others, price, warranty, Speed, Tank Capacity and Technology. The end result of this research is the result of the priority criteria of the motor, which is ranked from highest to lowest, so that the buyer can easily make decisions by looking at these results.
Pembuatan Aplikasi Sistem Informasi Kesehatan (SIFKES) untuk Meningkatkan Integrasi Data Puskesmas di Kota Jambi Berbasis Web Service
Authors: Puad Lailyn , Adriana Windy
Published: June 2019

Health is one parameter that is often used as a measure of the welfare of a region. Jambi City has 20 health centers spread across 8 sub-districts and has a duty to serve the entire community of Jambi City. The classic problem that always arises in the integration of data raises a mature unsuitability to the accuracy of the patient's diagnosis. Web services are the perfect answer to use as a data centralization medium, with their superiority in terms of capacity, speed and security of the web service very apt to be implemented in the integration of crucial data such as health data. Supported by artificial intelligence applied to be used as an assistant to the role of a physician in the diagnosis process, this application is suitable for use on every line of health institutions as a step to improve the quality of service to the community.
Sistem Informasi Madrasah Aliyah Negeri Pagar Alam Berbasis Web
Authors: Mukti Yogi Isro'
Published: June 2019

Madrasah Aliyah Negeri Kota Pagar Alam is a competency oriented madra-sah that is forward-looking in building nation, one of them is by utilizing information technology. Currently the utilization of information technology continues to be pursued, such as means of dissemination of information. But now the dissemination of information is still limited, because it takes a technology that is able to overcome the problem. One of the global information dissemination technology is website that can be built by using web engineering system and modeling method using UML (Unified Modeling Language) such as use case diagram, class diagram, activity diagram, sequence diagram. In addition to preparing the implementation of this Information System, the author uses the PHP programming language and MySQL database.
Perancangan Sistem Informasi Pengolahan Data Keuangan pada Titipan Mobil Setiya Menggunakan Bahasa Pemrograman PHP dan Database MYSQL
Authors: Mardison Mardison
Published: June 2019

This study aims to design a system of financial data processing information on Titipan Mobil Setiya. Setiya Car Setup is a car service provider business for car owners who want to travel out of town but hesitate to leave the vehicle at home. In the management of parking and transaction report making, Setiya Car Codes still use manual way, that is by recording through the book so that managers often experience mistake in making transaction report at the end of month. Therefore, we need a system that can collect data, process data, store data, look back data and distribute good information quickly, precisely and accurately, that is through information system of financial data processing by using object oriented programming technique, that is Unified Modeling Language (UML), PHP Programming Language, and MYSQL Database. With the design of this new information system, will facilitate the leadership and employees Setiya Car Titipan to serve customers, as well as accelerate the process of financial transactions and financial reporting.
Penerapan Metode Algoritma C4.5 dalam Menganalisa Pegajuan Kredit pada Koperasi Jasa Keuangan Syariah Kelurahan Limau Manis Selatan
Authors: Hadi Febri
Published: June 2019

The development of data processing techniques at this time has experienced rapid development. The Decision tree is a simple representation of a classification technique that is the process of teaching a function of purpose that maps each set of first attributes of a class defined previously. The decision tree can determine the hidden relationship between a number of potential target variables. In lending to customers, credit analysis is required for lending. The analysis of the kerdit can be done by utilizing data mining in the form of C4.5 algorithm. The C4.5 algorithm is used to provide credit decisions in order for the Sharia financial services cooperative to quickly analyze the credit application by members of a cooperative. The purpose of this research is to apply C4.5 algorithm method in analyzing credit application at Koperasi Jasa Keuangan Syariah Kelurahan Limau Manis Selatan.
Perancangan Alat Pendeteksi Golongan Darah dan Rhesus dengan Menggunakan Mikrokontroler Arduino Mega 2560
Authors: Syahputra Hadi , Rahman Sepsa Nur
Published: June 2019

The aim of the research is to design the tools used to detect and determine blood type. Blood and rhesus group detection can usually be done manually through a process of testing red blood cells with antisera (serum) to see if blood that has been given antisera (serum) occurs agglutination (agglutination) or non-agglutination (not clot). In this study, blood type and rhesus detection was designed electronically using ABO blood type and Rhesus system. It is designed using three pairs of light sensor, LED sensor as transmitter and Photodioda as receiver, comparator circuit and arduino mega 2560 microcontroller. Agglutination sensor or non-agglutination reaction of blood sample mixed with antisera. Next, it sends the voltage to be conditioned by the comparator circuit then sent to the microcontroller for processing and the blood type and rhesus readings will be displayed on the LCD screen.
Perancangan Aplikasi Lembar Kerja Digital terhadap Pengambilan Nilai di Kampus ANH
Authors: Taqwiym Akhsani
Published: June 2019

In the world of education, technology is not only used to seek information and disseminate information, but technology is also used for the assessment of the achievement of learning objectives. At this time, to determine whether or not a learning goal is achieved, it is usually measured only on the value derived from the manual tests performed. Through the process of making the value is done manually, then the time required for decision making becomes inefficient. Therefore, it is necessary to design an application of the value-taking system using the Digital Worksheet (LKD). System development tools used include: process model, data flow diagram, and data model. With this application is expected students can complete the task better and help the process of taking the value to know whether or not achieved learning.
Aplikasi E-Office Berbasis Web pada STMIK Indonesia Padang
Authors: Efendy Zainul , Genda Azizel Wanjas Saputra
Published: June 2019

This study aims to create an E-Office application program that can perform data processing of incoming mail and outgoing mail STMIK Indonesia Padang and can provide solutions to problems processing data systems incoming mail and outgoing mail is still done manually. With this application processing of incoming and outgoing mail data becomes automatic such as reports and disposition letter. The proposed application can simplify the processing, searching, and displaying the attachments of the incoming and outgoing mail data required. E-Office application on STMIK Indonesia Padang is made by using PHP 5.0 programming language supported by MySQL database and System Development Life Cycle (SDLC) design. With E-Office Application, data and attachment of incoming and outgoing mail at STMIK Indonesia Padang can be processed with a relatively short time and the report produced more accurate.