bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of Marketing Mix to Increase Meeting Events
Authors: Kadek Wirantari  , I Nyoman Rajin Aryana  , I Ketut Sutama  , I Gede Mudana  , Made Ruki  , I Gusti Agung Bagus Mataram
Published: August 2022

ABSTRACT

Purpose: This study aims to analyze the application of marketing mix in this case 7Ps (product, price, place, promotion, people, process, and physical evidence) in increasing the number of meetings at a 5-star hotel located in Kuta area, Bali, Indonesia.

Research methods: Data collection was carried out by observation, interviews, documentation, and questionnaires with a total of 150 respondents from professional conference organizers who had held a meeting at the hotel. The analysis technique used in this study is qualitative and quantitative analysis. 

Results and discussion: The implementation of the marketing mix applied by the hotel is such as providing a meeting place including facilities and meeting equipment, providing prices following client budgets, promoting using brochures, websites, through sales calls and telemarketing, routinely checking the conditions of the meeting place. The most effective variable influencing the increase in the number of meeting events is by looking at the results of the beta standard coefficient of the largest value, namely the physical evidence variable with the largest value of 0.266 with sig 0.00 which means that the physical evidence variable most effectively influences the number of meetings

Implication: The factors causing the ineffectiveness of the variable of the marketing mix based on the results of the interview are less than optimal employee performance and promotions that are carried out less and are less effective in selling meeting packages.

Keywords: marketing mix, meeting events, multiple linear analysis regression.
IMPLEMENTASI HAK PENDIDIKAN ANAK PERSPEKTIF AL-QUR’AN DI SDS JAKARTA ISLAMIC SCHOOL
Authors: MS Farizal , Surahman Hendra
Published: August 2022

This research is a field research with a descriptive qualitative approach. Implementation of the Right to Education of Children from the Al-Qur'an Perspective at SDS Jakarta Islamic School, Joglo, Kembangan, West Jakarta. Problems that are within the scope of a family and school in the form of children's delinquency, disobedience to their parents and teachers, lack of attention from their parents and so on identify that there are problems in the family and in the learning place, then to what extent the position of educators and families can provide rights education for students and or their children in accordance with the teachings of Islamic law through the perspective of the Qur'an. There are seven children's rights that they must always receive and receive from their parents and educators, including: the Right to Faith and Tawhid Education, the Right to Worship Education, the Right to Moral Education, the Right to Physical Education, Furthermore, the Right to Intellectual Education, the Right to Mental Education and ends with the Right to Education. Social. So, by implementing the right to Al-Qur'anic Children's Education at SDS Jakarta Islamic School, West Jakarta, it has made a good and positive contribution to the educational development of students
Application of Multi-Criteria Decision-Making in Achieving the Right Mix Asphalt Mixtures
Authors: A. A. Rassafi  , M. Zarei  , A. Dadashi
Published: August 2022

Marshall Test is one of the tests used for asphalt mixture. This test has six parameters, including stability, unit weight, flow, void in mineral aggregate, voids in total mix, and voids filled with asphalt. Further, the additional cost of various additives to the asphalt mixture for building one kilometer of the road is a negative parameter. However, using additives improves the technical characteristics of the asphalt mixture. Therefore, making a proper choice among the alternatives would be a hard task. This paper tries to provide an appropriate method for mixing the design of asphalt mixtures to select the best alternative by considering all technical criteria. For this purpose, the concordance analysis method, which is one of the compensation models of the Multi-Criteria Decision-Making (MCDM), was used. The results showed that the concordance analysis method using a pairwise comparison strategy combines the different criteria to prioritize alternatives and to propose the best alternative. Therefore, this method can be used as a superior method for mixing the design of asphalt mix compared to conventional methods.
Strength properties of Fly Ash based Geopolymer Concrete cured at different temperatures
Authors: Dissanayake D. M. H. , Dissanayake D. M. A. K. , Pathirana C. K.
Published: August 2022

This paper presents the results of an experimental study of the effect of curing temperature on the compressive strength and split tensile strength of Geopolymer concrete (GPC) which is made using fly ash produced at Norochcholai coal power plant. A relationship between splitting tensile strength and compressive strength also is also developed using test data. The results are then compared with some expressions published in international literature. A mixture of Sodium Silicate and Sodium Hydroxide solutions was used to activate low calcium class F fly ash to form Geopolymers. All specimens were oven cured for 48hours where curing temperature was varied from ambient temperature to 80oC at 20oC intervals. One day of rest period was given to every sample before curing. Test results showed that curing temperature has a significant effect on rate of strength gaining of GPC. The output of this study has provided a better understanding of the correlation between splitting and compressive strengths of GPC, which has therefore helped to generate a new expression with better accuracy for GPC prepared using locally available fly ash.
Wille und Verstand
Authors: Möhle Hannes
Published: August 2022

According to our everyday concept, a morally attributable action has two prerequisites, namely the free decision between different options for action and the knowledge of what is being done, especially regarding the goal of action. During an intense debate on this topic at the end of the 13th and the beginning of the 14th century, William of Ockham takes into account this double requirement in his theory of action by understanding will and reason as partial causes of human activity. Thereby he asserts neither a voluntaristic intensification of the freedom of will, as he is often accused of doing so, nor a dominance of practical knowledge.
Transzendentale Theologie
Authors: Schaeffler Richard
Published: August 2022

Richard Schaeffler’s transcendental theology, as Rahner already attempted, wants to indicate what is talked about when God is spoken of in a secularised world that places all talk of God under suspicion of meaninglessness: Not the top of the pyramid of being or the scale of values is the primary place where God can be sought, but every object of experience and its claim on our looking and thinking can become the figure in which God meets man. For Schaeffler, experience is a dialogue that can only be conducted with the reality of the world because it deciphers the claim of the real as the present form of a free divine address.
Unraveling Pathophysiological Link Between Mitophagy Pathway and Vascular Dementia
Authors: Kumas-Kulualp Meltem , Altintas Kadirhan Ozge , Demirci Mehmet
Published: August 2022

Context: Vascular dementia (VaD) is the second most common type of dementia after Alzheimer’s disease worldwide. Vascular dementia is a neurodegenerative disorder characterized by gradual cognitive impairment. Ischemic and hemorrhagic strokes result in VaD, markedly distributing cerebral blood flow and decreasing patients’ cognitive and memory performance. Due to their high energy demands, neurons are more sensitive to cellular architecture changes and exposed to mitochondrial stress than other cell types. Mitochondrial dysfunction and selective autophagy of mitochondria, known as mitophagy, are associated with VaD. This review aims to elucidate the association between mitophagy and VaD. Evidence Acquisition: This review was conducted independently by at least two researchers dominant in various VaD studies. We searched databases including Elsevier, Google Scholar, and PubMed using the terms ‘vascular dementia’, ‘vascular cognitive impairment’, and ‘mitophagy’. We evaluated 70 articles on the relationship between VaD and mitophagy and interpreted the results. Adobe Photoshop 2022 was used for drawing figures by researchers. Results: The autophagy process plays a protective role in experimental VaD models via preserving vascular integrity and the structure of the blood-brain barrier, upregulating occludin and claudin protein expressions, reducing oxidative stress, and decreasing cognitive dysfunction. Some studies claim that autophagy could have adverse effects in a time-dependent manner against neuronal injury. Prolonged autophagy and overexpressed autophagic proteins induce ischemic injury and cause neuronal cells to undergo apoptotic cell death. Conclusions: Although there are limited studies on the activation of mitophagy-related pathways in VaD, and the definitive role of mitophagy in neuronal healing is unclear, further research is needed to elucidate mitophagy pathways in neurons.
Cell Toxicity Effect of the Extract of Medicinal Plants against Human Breast (MCF7 and KBR3) Cancer Cell Lines
Authors: Mojodi Elham , Doostabadi Mohammad Reza , Sabbagh Seyed Kazem , Mohammadpanah Monireh , Haghiralsadat Bibi Fatemeh , Maleki Behnam
Published: August 2022

Background: Breast cancer is the most lethal cancer causing death among women, especially in developed countries. Using medicinal plants and natural resources to control and prevent different types of cancer in human has been the focus of attention. Objectives: The current study aimed to investigate the possible effects of hydroalcoholic extracts from some plant species such as Lavandula angustifolia, Ephedra major, and Scenedesmus obliquus on cell viability of two breast cancer MCF7 and SK-BR3 cell lines. Methods: MTT assay and gene expression analysis were performed adopting qRT-PCR method. Target cells were treated with different concentrations of plant extracts in a 24-hour period. Data were analyzed using Graphpad Prism version 8.3.0. Differences among means were determined using Student’s t-test or one-way ANOVA with Dunnett’s Multiple Comparison Test. Results: An indirect relationship was detected between extract concentration and cell viability. The result of the cell viability (IC-50) showed that the extract of S. obliquus had the maximum effect on both tested cells at concentrations above 100 µg/mL. A high cell death rate was observed in MCF-7 cell line compared to SK-BR3 cell line 24 h after the treatment. According to results from gene expression analysis, Caspase 3 gene increased in all treated cells, while the bcl-xl gene expression declined in the tested cells. Conclusions: It was concluded that the extracts from three plants had both positive and dose-related effects on MCF-7 and SK-BR3 cell line. However, it was recommended that future complementary studies should be conducted in order to evaluate the cell viability effect of these plants on human cancer.
Prevalence of Hepatic Space-Occupying Lesions Based on Sonographic Findings in Patients Referred to Guilan Cohort Center, Iran
Authors: Alizadeh Ahmad , Joukar Farahnaz , Ghorani Najmeh , Mansour-Ghanaei Alireza , Tabatabaii Mohammadjavad , Faraji Niloofar , Zeinali Tahereh , Naghipour Mohammadreza , Mansour-Ghanaei Fariborz
Published: August 2022

Background: Early diagnosis of hepatic lesions can result in more successful treatment. Objectives: The present study aimed to diagnose hepatic space-occupying lesions by sonography in Guilan Cohort Center participants. Methods: In this cross-sectional prospective epidemiological research studies of Iranian adults (PERSIAN) Guilan cohort study (Sowme'eh Sara, Guilan, Iran) conducted in 2014 - 2017, the sample included 960 individuals of both genders, aged 35 - 60 years. A radiologist examined all individuals with sonography to determine hepatic space-occupying lesions. Demographical and clinical characteristics were recorded via a questionnaire. Data analysis was performed using SPSS software (version 16). Results: Only 2.3% of the patients were diagnosed with hepatic lesions such as hemangioma, hepatic cysts, and other lesions with frequencies of 1.1%, 0.8%, and 0.4%, respectively. Also, there was a significant relationship between gender and the presence of hepatic lesions (P < 0.05). The frequencies of hepatic lesions were 1.7% and 3.6% in men and women and 1.6%, 2.5%, and 4.4% in the age groups of 35 - 45, 45 - 55, and over 55 years, respectively. Conclusions: Hemangioma was the most common hepatic lesion diagnosed in ultrasonography examinations. Moreover, the only factor influencing the frequency of hepatic lesions was gender, which was found twice more in women than in men.
Investigation of the Hourly and Spatial Patterns of Traffic Offenses During March-April 2019 in Iran Using Bivariate Generalized Additive Models and Integrated Nested Laplace Approximation
Authors: Fayaz Mohammad , Abadi Alireza , Razzaghi Alireza , Khodakarim Soheila , Hosseini Mostafa
Published: August 2022

Background: The control, management, and prevention of driving accidents and risky driving are regarded as concerns for numerous countries, according to the World Health Organization. In this regard, many technologies, such as count stations, are recommended. They count traffic offenses, such as speeding and unsafe distance, hourly and daily, and have different patterns according to the hour of the day and the location. Objectives: This study aimed to investigate the risky driving behaviors according to traffic offenses in Iran and estimate their hourly and spatial patterns using generalized additive models (GAMs) and stochastic partial differential equation methods. Materials and Methods: There were 2,316 count data stations for one month within March-April 2019. This study estimated the hourly average of each traffic offense, Pearson’s and Spearman’s correlations, and the energy statistics for testing the bivariate normal distribution. There are five distributions, such as univariate Poisson, quasi-likelihood Poisson, Gaussian, location-scale Gaussian, and bivariate Gaussian in GAMs, to study the hourly patterns which were compared to the mean squared error (MSE) and correlation. Results: The hourly average of total vehicles and number of speeding and unsafe distance offenses per count station had positive skew distributions with mean values equal to 347 ± 456, 22.5 ± 44.2, and 65.9 ± 150, respectively. The correlation between traffic offenses in most provinces was significant, not large, and different. The GAM with the bivariate Gaussian distribution had the best performance according to the MSE and correlation. It revealed three hourly patterns for count predictions; the first was that speeding is higher than unsafe distances; the second was that unsafe distances are higher than speeding; the third was that speeding and unsafe distances do not have a specific pattern in some hours. The percentage of speeding was higher in the central, northeast, and southeast regions than in other parts of Iran, and the percentage of unsafe distances was higher for the north, northwest, west, and some parts of the southwest than in other parts of Iran, respectively. Conclusions: The hourly pattern of traffic offenses exists and has a complex structure. The spatial pattern of traffic offenses shows the riskiest points in Iran.
Prevalence of Plasmid-Mediated Quinolone Resistance Genes and Molecular Typing of Klebsiella pneumoniae Isolates from Blood Cultures in Milad Hospital, Tehran, Iran, Within 2018 - 2019
Authors: Ghane Maryam , Babaeekhou Laleh , Asgharifard Morteza
Published: August 2022

Background: Plasmid-mediated quinolone resistance (PMQR) determinants are commonly characterized in Klebsiella pneumoniae isolates worldwide and complicate the treatment of infections caused by this bacterium. Objectives: This study aimed to investigate the prevalence of PMQR determinants and molecular typing of blood isolates of K. pneumoniae in Milad hospital in Tehran, Iran, within 2018 - 2019. Methods: A total of 100 K. pneumoniae isolates were tested for susceptibility to quinolones using the disk diffusion method. The minimum inhibitory concentrations (MICs) of ciprofloxacin (CIP) and levofloxacin (LEV) were determined using the microdilution broth method. The PMQR determinants were detected by polymerase chain reaction (PCR) assay, and the genetic relationship between the isolates was assessed using enterobacterial repetitive intergenic consensus (ERIC)-PCR. Results: The resistance rates of the isolates to LEV, CIP, nalidixic acid, and norfloxacin were determined to be 62, 46, 29, and 23%, respectively. Eighty-one isolates were resistant to at least one tested quinolone. A high-level CIP and LEV resistance (MIC > 32 mg/L) was observed in 15 (18.51%) and 36 (44.44%) isolates, respectively. The PMQR genes were detected in 71 (87.65%) isolates. The oqxAB, qnrS, qnrD, qnrB, aac(6')-Ib-cr, qnrA, qepA, and qnrC genes were detected in 71 (87.65%), 30 (37%), 25 (30.8%), 24 (29.6%), 18 (22.2%), 17 (21%), 17 (21%), and 8 (9.9%) isolates, respectively. The ERIC-PCR revealed 64 genotypes among quinolone-resistant isolates. Conclusions: The high prevalence of PMQR genes observed in this study is a significant concern for public health since they can contribute to the spread of fluoroquinolone resistance among clinical isolates. The ERIC-PCR revealed high heterogeneity among the studied isolates, indicating that they emerged from different sources.
Know-Nothing Nihilism: Pandemic and the Scandal of White Evangelicalism
Authors: Harrington Michelle A. ,   Philosophy Documentation Center
Published: August 2022

White evangelical habits of mind and idolatrous allegiances propped up a devastatingly irresponsible political administration; I argue that the COVID-19 pandemic should be viewed as an apocalypse: “a catastrophic revelation”—in this case, of Christian responsibility refused. I engage the works of Christian historians Mark Noll and Kristin Kobes Du Mez to interrogate how evangelical habits of mind and heart have nurtured anti-intellectualism, credulousness, and the uncritical adoption of neoliberal economic individualism before turning to a constructive Christian realist call for “nasty” (honest, embodied) thinking and genuine repentance which draws from Andrew DeCort’s Bonhoeffer scholarship.
Intersections and Methods in Disability Theology: Bioethics and Critical Studies as Dialogue Partners
Authors: Stahl Devan , Curry Leonard ,   Philosophy Documentation Center
Published: August 2022

Disability theology has been a small but growing field over the past thirty years. This paper reviews the current methods used in the discipline and proposes ways to move the field forward. Two intersections between disability studies and Christian theological ethics are explored in particular: bioethics and critical theory. Bioethics helps to address the material health and wellbeing concerns of people with disabilities and the discriminatory attitudes about disability that stem from the medical field. Critical theory on the other hand, examines disability through cultural productions that shape our ableist imaginary. Critical theory offers resources for countering or “disciplining” our imaginations. Both bioethics and critical theory offer unique entry points into disability, but each also contains limitations that reveal why disability theology must continue to engage multiple methods and discourses.
Aquinas vs. Buridan on the Universality of Human Concepts and the Immateriality of the Human Intellect
Authors: Klima Gyula ,   Philosophy Documentation Center
Published: August 2022

Under the traditional classification of medieval positions on the issue of universals, both Aquinas and Buridan would have to be deemed to be “conceptualists”: they both deny the existence of mind-independent, Platonic universals (against “realists”), and they both attribute universality primarily to the representative function of our universal concepts, and thus only secondarily to universal names of human languages (against “nominalists”). Yet, Aquinas is quite appropriately classified as a “moderate realist,” and Buridan as an “Ockhamist nominalist.” This paper will argue that what justifies these more refined classifications is the two authors’ radically different conceptions of the representative function of our universal concepts. The paper will show how this difference results in their opposing judgments concerning the demonstrability of the thesis of the immateriality of the human intellect and will reply to Buridan’s main objection to Aquinas’s argument for this thesis, by pointing out the objection’s conflation of merely indifferent, non-distinctive singular representation with genuinely universal intellectual representation. In its conclusion, the paper will briefly gesture at an important contemporary implication of Aquinas’s thesis concerning a metaphysical limitation of artificial intelligence.
Countering MacKinnon on Rape and Consent
Authors: Anderson Erik A. ,   Philosophy Documentation Center
Published: August 2022

Feminists are divided on whether consent should be employed in legal definitions of rape. Catharine MacKinnon has criticized the usefulness of consent in enabling legal systems to recognize and prosecute instances of rape (MacKinnon 1989, 2005, 2016). In a recent article in this journal, Lisa H. Schwartzman defends the use of affirmative consent in rape law against MacKinnon’s critique (Schwartzman 2019). In contrast to MacKinnon, Schwartzman claims our understanding of rape must include both force and consent components. In this paper, I will argue in agreement with Schwartzman and against MacKinnon that the legal definition of rape should include an affirmative consent component. I will take Schwartzman’s discussion as my point of departure and consider whether she has responded adequately to MacKinnon’s criticisms of consent. I will argue that her responses are not fully adequate. In particular, she has not successfully rebutted the argument that an appeal to consent is unnecessary once we have accepted an expanded definition of coercion. I will then provide a more affirmative defense of affirmative consent in response to MacKinnon’s most challenging criticism.
Mellem design, didaktik og diskurs
Authors: Hansen Thomas Illum , Gissel Stig Toke
Published: August 2022

I denne artikel præsenteres resultater fra en undersøgelse af det adaptive læremiddel, Rhapsode, til matematik i grundskolen ud fra et tredimensionelt fokus, der omfatter diskurs, didaktik og design. Vores formål med den flerstrengede analysestrategi er dels at sætte (fag)didaktikken i centrum, dvs. hvad vi vil med faget, og hvad den det adaptive design gør ved fagligheden, dels at sætte den adaptive teknologi ind i en større diskursiv kontekst. Dette står i kontrast til det snævre fokus på at udvikle effektive adaptive maskiner, der ellers præger forskning inden for feltet. Resultatet er et skærpet fokus på den dilemmafyldte brug af adaptiv teknologi. Analysen peger på, at der både er behov for a) redesign og udvikling af den didaktiske rammesætning af læremidlets adaptivitet, b) redidaktisering og nyfortolkning af det didaktiske potentiale i praksis samt c) regulering og demokratisk kontrol af de nye forretningsmodeller, der gør data og algoritmer til genstand for forretningsudvikling.
CSR at HEIs: Between Ignorance, Awareness and Knowledge
Authors:   Faculty of Management and Economics, Gdańsk University of Technology, Poland, Wasilczuk Julita E. , Popowska Magdalena ,   Faculty of Management and Economics, Gdańsk University of Technology, Poland
Published: August 2022

Purpose: This paper focuses on CSR education in the Higher Education Institutions. It analyzes current approaches to this education and the enhancements already deployed in the international perspective. The main aim is to conceptualize on CSRS education forms within the context of technology-oriented HEIs and propose the model for this education. This model has also been partially verified using the cases of four technical universities. Design/methodology/approach: This research uses qualitative and quantitative research methods. The literature review is applied to trace HEIs’ educational and organizational CSR commitment methods. Based on this review, we proposed a model of CSRS education in HEIs. Using this model, we checked to what extent its elements are used in four technical universities from: Latvia, Lithuania, Ukraine and Poland. For this purpose, educational programs at universities were analyzed. We also confronted the activity of these universities with the students’ knowledge about CSRS. The results of the survey conducted among 3,424 students from these universities contributed to elaborating on this aspect. Findings: The results confirm that students are ignorant of CSR, even those studying at business faculties. What is surprising, even those students who are business owners do not demonstrate a high level of knowledge about CSR. Universities, on the other hand, do not offer the possibility of eliminating this ignorance. Meanwhile, we believe they can do so not only through the standing-alone CSRS education but also by including CSR in other courses and by giving a good example. Research limitations/implications: Due to language barriers, the submitted model was only partially verified at selected universities. We are also aware that the described situation may be one-sided as the four cases presented in this study are homogeneous, as they represent technical universities, so only one profile among a variety of universities’ profiles (technical versus humanities versus economic). Moreover, the conducted research covered students and universities from Central and Eastern Europe, which might also have an impact on the obtained results. Originality/value: Bearing in mind the current level of implementation of education in the area of CSR and the results of the research carried out, we propose a model of education that includes three pillars: a good example of a university (socially responsible university), responsible managers education (RME) and raising awareness among students of non-business faculties (ASR). At the same time, we indicated a large gap between the educational needs in the area of CSRS and the offer of four technical universities.
Artificial Intelligence as a Tool Supporting Organizational Entrepreneurship – Theoretical Problems and Case Analysis
Authors:   Faculty of Management, University of Warsaw, Poland, Kisielnicki Jerzy , Zadrożny Jan , Fabisiak Sebastian
Published: August 2022

Purpose: This article aims to present the results of qualitative research on the analysis of the relationship between artificial intelligence (AI) and organizational entrepreneurship. The purpose of this research is to determine, in terms of qualitative analysis, what kind of relationships are taking place. AI is part of a new trend in the development of digital technology, defined by the acronym DARQ. Its elements are the following digital systems: Distributed Ledger, Artificial Intelligence, Extended Reality, Quantum Computing. Methodology: The research procedure consists of the following stages: a literature analysis, qualitative research in the focus group, evaluation by experts, and the presentation of results, conducting three case analyses from various industries during the activity, which present the extent to which AI affects organizational entrepreneurship. Results: The research showed user support for the use of AI technology, especially in the implementation of procedures that support organizational entrepreneurship. The AI applied in the organization enables us to obtain effects on such elements of organizational entrepreneurship as creating new strategic solutions, evaluating these proposals, and monitoring the approach of the organization’s management through the use of tools such as a management cockpit and simulation models. The use of artificial intelligence in a modern organization is necessary to improve multifaceted and interdisciplinary processes that support organizational entrepreneurship. The use of AI shows the usefulness of digital technology in operational and strategic management. Limitations: Due to the lack of empirical, especially quantitative, materials concerning the application of all levels of categorization of the use of artificial intelligence in the discussed cases, supplementary research is required to provide a more comprehensive analysis of its applications. Originality/value: The thesis was justified that IT systems containing AI technology solutions are helpful in the implementation of procedures supporting organizational entrepreneurship. The thesis is complemented by a study consisting of examining the truthfulness of the statement that the consequence of using AI is to obtain in an organization the effects of both generating proposals for new development solutions and verifying the feasibility of the implementation of the procedures proposed by the organization management. The conducted research focuses on the assessment of the relationship between advanced information technologies and organizational entrepreneurship.
Non-Hermitian skin effect in a domain-wall system
Authors: Deng Tian-Shu ,   Institute for Advanced Study, Tsinghua University, Beijing 100084, China
Published: August 2022

The non-Hermitian skin effect is one of the most striking features in non-Hermitian physics. It reveals a novel phenomenon in a non-Hermitian system that the bulk wave function and energy spectrum are sensitively dependent on the boundary conditions. The concept of generalized Brillouin zones has been proposed to characterize bulk wave functions in such systems . Based on generalized Brillouin zones, non-Bloch topological invariants can reconstruct the non-Hermitian bulk-edge correspondence. Previous discussion of the non-Hermitian skin effect mainly focused on open boundary conditions, and the calculation of generalized Brillouin zones needs to be reconsidered under domain-wall boundary conditions. The paper introduces the related researches of the non-Hermitian skin effect in domain-wall systems, including the general form of the generalized Brillouin zone equation in a one-dimensional single-band model, non-Bloch topological invariants in non-Hermitian SSH (Su-Schieffer-Heeger) model, and the experimental realization of the non-Hermitian skin effect in one-dimensional quantum walk system.
The blunted vascular endothelial growth factor-A (VEGF-A) response to high-altitude hypoxia and genetic variants in the promoter region of the VEGFA gene in Sherpa highlanders
Authors: Droma Yunden , Hanaoka Masayuki , Kinjo Takumi , Kobayashi Nobumitsu , Yasuo Masanori , Kitaguchi Yoshiaki , Ota Masao
Published: August 2022

Background

Sherpa highlanders demonstrate extraordinary tolerance to hypoxia at high altitudes, which may be achieved by mechanisms promoting microcirculatory blood flow and capillary density at high altitudes for restoring oxygen supply to tissues. Vascular endothelial growth factors (VEGFs) are important signaling proteins involved in vasculogenesis and angiogenesis which are stimulated by hypoxia. We hypothesize that the VEGF-A, the major member of the VEGF family, and the gene encoding VEGF-A (VEGFA) play a part in the adaptation to high-altitude hypoxia in Sherpa highlanders.

Methods

Fifty-one Sherpa highlanders in Namche Bazaar village at a high altitude of 3,440 meters (m) above sea level and 76 non-Sherpa lowlanders in Kathmandu city at 1,300 m in Nepal were recruited for the study. Venous blood was sampled to obtain plasma and extract DNA from each subject. The plasma VEGF-A concentrations were measured and five single-nucleotide polymorphisms (SNPs, rs699947, rs833061, rs1570360, rs2010963, and rs3025039) in the VEGFA were genotyped. The VEGF-A levels and allelic frequencies of the SNPs were compared between the two populations.

Results

A significant difference in oxygen saturation (SpO2) was observed between the two ethnic groups locating at different elevations (93.7 ± 0.2% in Sherpas at 3,440 m vs. 96.7 ± 0.2% in non-Sherpas at 1,300 m, P < 0.05). The plasma VEGF-A concentration in the Sherpas at high altitude was on the same level as that in the non-Sherpas at low altitude (262.8 ± 17.9 pg/ml vs. 266.8 ± 21.8 pg/ml, P = 0.88). This result suggested that the plasma VEGF-A concentration in Sherpa highlanders was stable despite a high-altitude hypoxic stimulus and that therefore the Sherpas exhibited a phenotype of blunted response to hypoxic stress. Moreover, the allele frequencies of the SNPs rs699947, rs833061, and rs2010963 in the promoter region of the VEGFA were different between the Sherpa highlanders and non-Sherpa lowlanders (corrected P values = 3.30 ×10−5, 4.95 ×10−4, and 1.19 ×10−7, respectively).

Conclusions

Sherpa highlanders exhibited a blunted VEGF-A response to hypoxia at high altitudes, which was speculated to be associated with the distinctive genetic variations of the SNPs and haplotype in the promoter region of VEGFA in Sherpa highlanders.
Effect of Moringa Oleifera Leaf Powder Supplementation in Children with Severe Acute Malnutrition in Gwalior District of Central India: A Randomised Controlled Trial
Authors: Yadav Hemant , Gaur Ajay , Bansal Satvik Chaitanya
Published: August 2022

Introduction: Child malnutrition is a major public health problem with a significant impact on child survival. In order to tackle this it is important to improve the nutritional quality of complementary and supplementary food while making it inexpensive and easily available. Moringa oleifera is a commonly grown local plant, with high nutritional and medicinal value, can be used as supplement. Aim: To assess the effect of Moringa oleifera leaf powder supplementation on children with Severe Acute malnutrition (SAM) during facility-based care and home-based care. Materials and Methods: This randomised controlled trial was conducted in the Severe Malnutrition Treatment Unit (SMTU) of Kamla Raja Hospital, Gwalior. A total of 100 children in the age group of 7 months -59 months admitted between November 2019 to October 2020, who fulfilled the World Health Organisation (WHO) recommended criteria for identification of severe acute malnutrition were included in the study. The children were randomised to routine supplementation alone (control group) and routine supplementation with Moringa leaf powder (intervention group). The anthropometric data was collected at the time of admission to the SMTU, at the time of discharge and every 15 days post discharge for two months. Uunpaired t-test, Chi-square test and fisher exact were used for statistical analysis. Results: There was significant weight gain (p=0.012) in the intervention group as compared to the control group. Similarly the number of children with severe wasting were significantly less (p=0.032) in the intervention group at the end of two months followup. There was no significant difference in height, Head Circumference (HC), Chest Circumference (CC), Mid Upper Arm Circumference (MUAC), Subcutaneous Fat Assessment (SCFA), complications observed between both the groups and duration of hospital stay. Conclusion: The use of Moringa oleifera leaf powder supplementation resulted in improved weight gain and reduction in severe wasting at the end of two months. It has the potential to link both facilities based and home based care of malnourished children.
Shipping Management System
Authors: eka Sn , Antony Blessing , Mahajan Promoth , kalyani Nithya
Published: August 2022

The SHIPPING MANAGEMENT SYSTEM is the subject of this project. The system is utilised for routine tasks including scheduling a courier, tracking courier history, and maintaining employee and branch details. The Shipping management system is the subject of this project. Daily tasks like booking, booking history, employee information, branch information, and pickup centres are handled by the system. To carry out this procedure manually is really challenging. Since the world is becoming more and more dependent on technology and information, it is therefore advised to computerise the process by creating the appropriate software. Utilizing the right technology to assist administrators in managing information is known as computerization of the shipping management system. When technology uses the most plentiful domestic resources and saves money and skilled labour, it is deemed acceptable. This project deals with the upkeep of booking information, incoming courier information, courier non-delivery information, and courier return information, among other things. The primary goal of this project is to automate shipping management maintenance. This projects front end and back end code are both written in PHP.
O princípio da desmercantilização nas políticas sociais
Authors: Zimmermann Clóvis Roberto , Silva Marina da Cruz
Published: August 2022

O presente artigo objetiva tecer discussões sobre um princípio inovador, denominado de desmercantilização, formulado recentemente por Esping-Andersen (1990, 1999, 2002) e incorporado ao estudo das políticas sociais. A principal proposição do autor, através deste termo desmercantilização, consiste em avaliar o grau de autonomia e independência dos indivíduos em relação ao mercado. As conclusões essenciais advindas da análise em tela evidenciam uma contribuição singular e inovadora, ao enfatizar a importância dos arranjos institucionais das políticas sociais, considerando não somente os direitos e garantias, mas, sobretudo, o entrelaçamento do Estado com o mercado e a família na provisão de políticas sociais. PALAVRAS-CHAVE: desmercantilização, políticas sociais, proteção social, Estados de Bem-Estar Social. THE PRINCIPLE OF DECOMMODIFICATION IN THE SOCIAL POLITICS Clóvis Roberto Zimmermann Marina da Cruz Silva The present paper discusses an innovative principle, denominated of decommodification, formulated recently by Esping-Andersen (1990, 1999 2002) and incorporated to the study of social policies. The author’s main proposition, through the term decommodification, consists of evaluating the degree of autonomy and independence of individuals in relation to market. The essential conclusions from this analysis evidence a singular and innovative contribution, when emphasizing the importance of the institutional arrangements of the social policies, considering not only rights and warranties, but, above all, the interlacement of the State with market and family in the provision of social policies. KEYWORDS: decommodification, social policies, social protection, Welfare States. LE PRINCIPE DE DECOMMODIFICATION (DEMARCHANDISATION), DANS LES POLITIQUES SOCIALES Clóvis Roberto Zimmermann Marina da Cruz Silva L’objectif de cet article est d’établir des discussions sur le principe innovateur de decommodification (démarchandisation), formulé récemment par Esping-Andersen (1990, 1999, 2002) et incorporé aux études de politiques sociales. En utilisant le terme decommodification (démarchandisation), l’auteur propose essentiellement d’évaluer le degré d’autonomie et d’indépendance des individus face au marché. Les principales conclusions découlant de l’écran d’analyse mettent en évidence une contribution unique et innovatrice qui montre l’importance des arrangements institutionnels des politiques sociales en considérant non seulement les droits et les garanties mais surtout l’imbrication de l’Etat avec le marché et la famille en termes de politiques sociales. MOTS-CLÉS: decommodification (démarchandisation), politiques sociales, protection sociale, Etats de BienÊtre Social. Publicação Online do Caderno CRH: http://www.cadernocrh.ufba.br
A SOCIOLOGIA COMO PROFISSÃO PÚBLICA NO BRASIL
Authors: Schwartzman Simon
Published: August 2022

É notável como, nas últimas décadas, a sociologia brasileira cresceu e se desenvolveu, adquirindo muitas das características de uma profissão. Duas  indagações, no entanto, decorrem desse processo. A primeira é a natureza dessa profissionalização – se ela se aproxima do modelo tradicional das “profissões cultas”, como a medicina ou direito, ou se aproxima mais daquilo que se denomina hoje de “profissão acadêmica”. A segunda é em que medida, nesse processo de profissionalização, a sociologia teria ou não perdido seu papel de “profissão pública”, e os sociólogos, seu papel intelectual. Isso leva a uma terceira questão, que é a da pertinência ou não de se esperar que a sociologia tenha e mantenha essa característica de profissão pública. PALAVRAS-CHAVE: sociologia pública, sociologia brasileira, sociologia crítica, sociólogos, profissões. THE SOCIOLOGY AS A PUBLIC PROFESSION IN BRAZIL Simon Schwartzman It is notable how, in the last decades, Brazilian sociology grew and evolved, and aquired many of the characteristics of a profession. Two questions, however, come from this process. The first is the nature of this professionalization – if it approaches the traditional model of the “educated professions”, as medicine or law, or if it approaches what is called today an “academic profession”. The second one is the measure, in this professionalization process, in which sociology would have lost or not its role as a “public profession”, and the sociologists, their intellectual role. And thus to a third question, that is the pertinence or not of expecting sociology to have and maintain this characteristic of public profession. KEY WORDS: public sociology, Brazilian sociology, critical sociology, sociologists, profession. LA SOCIOLOGIE EN TANT QUE PROFESSION PUBLIQUE AU BRESIL Simon Schwartzman Il est certain qu’au cours des dernières décennies la sociologie brésilienne a pris de l’ampleur, s’est développée et a acquis les caractéristiques d’une profession. Cependant deux questions découlent de ce processus. La première est de savoir quelle est la nature de cette professionnalisation – si elle se rapproche du modèle traditionnel des “professions savantes”, comme la médecine ou le droit, ou si elle se rapproche plutôt de ce qu’on appelle aujourd’hui “profession académique”. La deuxième est de savoir dans quelle mesure, au cours de ce processus de professionnalisation, la sociologie aurait ou non perdu son rôle de “profession publique”, et les sociologues leur rôle intellectuel. Ceci mène à une troisième question, celle de savoir s’il est pertinent ou non de s’attendre à ce que la sociologie ait et maintienne cette caractéristique de profession publique. MOTS-CLÉS: sociologie publique, sociologie brésilienne, sociologie critique, sociologues, profession. Publicação Online do Caderno CRH no Scielo: http://www.scielo.br/ccrh Publicação Online do Caderno CRH: http://www.cadernocrh.ufba.br
SOCIOLOGIA E ENGAJAMENTO EM PORTUGAL: reflexões a partir do trabalho e do sindicalismo
Authors: Estanque Elísio
Published: August 2022

O presente paper procura ser um exemplo da sociologia crítica-pública desenvolvida no Centro de Estudos Sociais (CES), da Universidade de Coimbra. A linha temática aqui tratada (sociologia do trabalho e do sindicalismo) assume uma perspectiva crítica, quer do ponto de vista teórico-reflexivo, quer como prática política do cientista social, consideradas duas faces da mesma moeda. Partindo desse ponto de vista, discute-se a atual conjuntura de crise e analisa-se o caso português à luz da questão do trabalho, realçando alguns dos traços estruturais do país como semiperiferia da Europa e mostrando como alguns dos seus atuais problemas têm origens muito antigas. PALAVRAS-CHAVE: sociologia pública, crise, trabalho, sindicalismo, Portugal.SOCIOLOGY AND ENGAGEMENT IN THE PORTUGAL: critical reflection on labour and trade unionism in a time of crisis Elísio Estanque This paper aims to be an example of the critical-public sociology that is produced at CES – Centre for Social Studies of the University of Coimbra. Focusing one specific research area (sociology of work and trade unionism), the critical perspective is assumed, both in theoretical and reflective terms, as well as political praxis of the social scientist. Considering this framework, the current crisis is taken as the starting point to discuss the portuguese case on the labour issue, stressing some structural lines of the country as a European semi-periphery and showing that some of its current problems have ancient roots. KEY-WORDS: public sociology, crisis, labour, trade unionism, Portugal. LA SOCIOLOGIE ET L’ENGAGEMENT AU PORTUGAL: réflexions à partir du travail et du syndicalisme Elísio Estanque Ce paper (travail) essaie d’être un exemple de la sociologie critique publique développée par le Centre d’Etudes Sociales (CES) de l’Université de Coimbra. Le thème que l’on aborde ici (sociologie du travail et du syndicalisme) assume une perspective critique autant d’un point de vue théorique et réflexif que d’une pratique politique des sciences sociales, aspects considérés comme les deux faces d’une même médaille. Partant de ce point de vue, l’actuelle conjoncture de crise est mise en discussion et le cas portugais est analysé à la lumière de la question du travail. Certains traits structuraux du pays sont mis en évidence tel que celui de semi périphérie de l’Europe et montrent combien quelques problèmes actuels ont une origine très ancienne. MOTS-CLÉS: sociologie publique, crise, travail, syndicalisme, Portugal. Publicação Online do Caderno CRH: http://www.cadernocrh.ufba.br