Comparative Assessment of Dynamics of Pathohistological Picture of Purulent Wound in Experimental Animals with a Model of a Boil in Head and Neck Area in Standard Treatment and when Using Electroa
Authors:   Belarusian State Medical University. 83, Dzerzhinski Ave., Minsk 220116, Republic of Belarus, Pohodenko-Chudakova I. O. ,   Association of oral and maxillofacial surgeons of the Republic of Belarus. 83, Dzerzhinski Ave., Minsk 220116, Republic of Belarus, Fleryanovitch M. S. ,   Educational Establishment Vitebsk State Medical University. 27, Frunze Ave., Vitebsk 210023, Republic of Belarus,   Association of oral and maxillofacial surgeons of the Republic of Belarus. 83, Dzerzhinski Ave., Minsk 220116, Republic of Belarus, Kolb E. L. ,   Belarusian State Medical University. 83, Dzerzhinski Ave., Minsk 220116, Republic of Belarus
Published: June 2021

The most common neodontogenic infectious and inflammatory processes affecting the skin are furuncles in the maxillofacial area. The task of effective treatment of patients with this disease is now becoming increasingly urgent which is largely due to the deterioration of the environmental situation, changes in the nature of nutrition and chronic stress. The purpose of the study is to make a comparative assessment of the results of the standard method of postoperative treatment and complex treatment using electroacupuncture based on the dynamics of the pathohistological picture of a purulent wound in experimental animals with a model of a boil in the head and neck. Materials and methods. Experimental studies were carried out on 20 guinea pigs of the same age and body weight, on which a model of a boil in the submandibular area was created. The boil was formed within 3 days, after which all experimental animals under local infiltration anesthesia underwent primary surgical treatment of the infectious and inflammatory focus with wound drainage. Then the animals were divided into two series. Series 1 received a standard treatment package in the postoperative period (antibiotics, daily dressings with mandatory drainage changes, instillation of the wound with antiseptic solutions). For series 2 of animals, the standard treatment was combined with an electroacupuncture treatment. The material for pathohistological examination was collected in the following terms: 3, 7, 14 and 21 days after the operation. Serial sections were made according to the standard procedure. The micro-preparations were examined using a light microscope. For comparison a descriptive method was used. Results and discussion. The most significant differences were found on the 21st day of observation when diffuse mononuclear cell infiltration of all layers of the dermis was detected in most of the series 1 micro-preparations which indicated the presence of productive inflammation. During the same period of observation, all the micro-preparations of series 2 showed a multilayered flat keratinizing epithelium without violating the integrity throughout. The papillary and reticular layers of the dermis showed no signs of inflammation. The appendages of the skin were traced throughout the entire field of vision without visible pathological changes. All of the above indicated no signs of inflammation. Conclusion. The results obtained clearly indicate the positive effect of electroacupuncture on both wound cleansing and the course of the processes of reparative regeneration of the skin