bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic variants of COVID-19 and vaccination. Is there a Correlation?
Authors: Nagwa Ali Sabri , Mohamed Ahmed Raslan , Eslam Mansour Shehata , Sara Ahmed Raslan
Published: March 2022

Background: New coronavirus disease is considered one of the most widely spreading viral infections all over the world. Increased numbers of severe covid-19 cases are growing up. Gene sequencing and discovering new viral variants is an essential aspect during the pandemic. The generation of treatment-resistant viral strains and the probability of negative impact on vaccination efficacy is possible. We aimed to review the probable effect of new variant emergence on treatment and vaccination efficacy, besides, the importance of gene sequencing from published literature data till the moment. Main body of the abstract: SARS-CoV-2 genome studies indicated that it shared 79 to 82% nucleotide similarity with SARS-CoV-1. Several gene locations in the envelope (E) structural protein c.222G>C (p. Leu74Leu) and the Membrane (M) structural protein c.213C>T (p. Tyr71Tyr) were proved to have mutations. Also, the surface (S) gene mutation c.1841A>G (p. Asp614Gly) is most relevant. The published sequences in Egypt are accounting for less than 0.2 percent of reported instances. Short conclusion: The possibility of rapid generation of treatment-resistant viral strains is highly possible. As a consequence of genetic alterations that impart functional differences in infectivity, sub-strains might arise as a result of acquired immunity that is likely to diminish over time and become less effective against increasingly aggressive strains. Gene sequencing in Egypt requires a lot of efforts to provide a rapid discovery for new emerging variants, to avoid a possible decrease in vaccination efficacy and emergence of treatment-resistant strains.
SARS-CoV-2 Infection and Viral Replication of Human Lung Organoids v1
Authors: Baumgardt Morris , Hülsemann Maren , Hoffmann Karen , Kessler Mirjana , Hippenstiel Stefan , C. Hocke Andreas , Hönzke Katja
Published: March 2022

This protocol describes the working steps to infect human lung organoids with SARS-CoV-2 and quantify the viral replication at defined time points post infection via plaque assay and viral E gene RT-qPCR.
Protein Extraction and Western Blot of Human Lung Organoids v1
Authors: Baumgardt Morris , Hülsemann Maren , Fatykhova Diana , Hippenstiel Stefan , C. Hocke Andreas , Hönzke Katja
Published: March 2022

This protocol describes the protein extraction from human lung organoids followed by western blotting. It gives a detailed description of the preparation of cell lysate from human lung organoids, followed by exact steps to perform a western blot and the immunostaining to detect ACE-2 as hostfactor of SARS-CoV-2.
Western Blot v1
Authors: Geertsma Haley
Published: March 2022

This protocol is used to western blot proteins-of-interest.
[RETRACTED] Twin Elements CBD Gummies Reviews - Does Gummy Candy Works? v1
Authors: not provided twingummiesreviews
Published: March 2022

[RETRACTED]

Twin Elements CBD Gummies Reviews - Does Gummy Candy Works?
[RETRACTED] Coral CBD Gummies - Reviews: Bad Complaints and Negative Side Effects? v1
Authors: CBD Gummies Coral
Published: March 2022

[RETRACTED]

Coral CBD Gummies
[RETRACTED] Staminon Male Enhancement Reviews 2022 v1
Authors: not provided staminonreviews
Published: March 2022

[RETRACTED]

Staminon Male Enhancement Reviews 2022
Testowy protokół v1
Authors: not provided lukasz.lukjaniuk
Published: March 2022

To testowa protokół do zrobienia czegos
Dracocephalum charkeviczii Prob. in vitro
Authors:   Federal Scientific Center of the East Asia Terrestrial Biodiversity FEB RAS, Gafitskaya Irina V. , Bezdelev Arkadii B. ,   Branch of National Scientific Center of Marine Biology FEB RAS, Scientific and Educational centre “Primorsky Aquarium", Nakonechnaya Olga V. ,   Federal Scientific Center of the East Asia Terrestrial Biodiversity FEB RAS
Published: March 2022

We established sterile clones of a medicinal plant dragonhead Dracocephalum charkeviczii Prob. (Lamiaceae). We used shoots of the plants from natural habitat, notably leaf nodes with axillary bud, as explants, sterilized the explants in 0.1 % Diocide for 4 minutes and cultivated them on agarized nutrient half-strength MS medium with vitamins, 2 % sucrose, 0.4 % agar, 1 mg/l indolylbutyric acid (IBA), or 0.5 or 1.0 mg/l 6-benzyladenine (BA). Medium pH was 4.6 or 5.4. We took hormonefree half-salt MS medium as a control. We observed the maximum propagation coefficient equal to 9.4 in microplants cultivated on the medium with 1 mg/l BA. Application of hormone-free MS medium can be recommended for D. charkeviczii propagation due to its simplicity. The use of the medium protocol with 1 mg/l BA on the first step and with IBA on the second step will allow rapid multiplication and establishment of full-fledged plants of D. charkeviczii for different purposes such as restoration of natural populations, source of valuable metabolites, landscaping, etc.
The vascular flora of the Sutai Khairkhan Mountain Nature Reserve, Mongolia
Authors:   Department of Biology, School of Mathematics and Natural Sciences, Mongolian National University of Education, Gundegmaa Vanjil , Dashmaa Tsogtbayar ,   Department of Biology, School of Mathematics and Natural Sciences, Mongolian National University of Education, Bilegtmandakh Chuntai ,   Department of Geography and Geology, Khovd University, Tsegmed Zagarjav ,   Laboratory of Flora and Plant Systematics, Botanic Garden and Research Institute, Mongolian Academy of Sciences, Norris Joscelyn ,   Reubenstein School of Environment and Natural Resources, University of Vermont, Oyuntsetseg Batlai ,   Department of Biology, School of Arts and Science, National University of Mongolia, Erst Andrey S. ,   Central Siberian Botanical Garden SB RAS, Baasanmunkh Shukherdorj ,   Department of Biology and Chemistry, Changwon National University
Published: March 2022

In this study we examined the floristic diversity of the Sutai Khairkhan Mountain Nature Reserve in western Mongolia’s Altai Mountain range. This nature reserve area was established in 2019 and compared to nearby reserves, its flora is relatively understudied. From field surveys in 2014, 2019, and 2020, we collected about 400 herbarium specimens from various habitats and different altitudes in the reserve. We identified total of 317 taxa including 10 subspecies and three varieties of vascular plants belonging to 157 genera and 45 families. Among these, five species are nationally endemic, 27 species are endemic to Altai Mountains, and 37 species are threatened, including two critically endangered, 11 endangered, 16 vulnerable, and eight near threatened. In addition, we rediscovered Microula tibetica var. pratensis (Maxim.) W.T. Wang after 40 years. This first complete checklist of the SKMNR flora amplifies the value of protecting the diverse and threatened plants in the reserve and creates a baseline to assess future population changes.
History and peculiarities of study of the Far Eastern species of Euonymus
Authors:   Russian State Agrarian University – Moscow Timiryazev Agricultural Academy, Savinov Ivan A.
Published: March 2022

The Russian Far East is of particular interest to monographers of the genus Euonymus, because this is where the northern distribution limits of many East Asian species are. At the same time, the main problem is different understanding of the scope and status of a number of taxa by Russian and foreign botanists. The article presents the chronology of the most prominent results of various authors, Russian and foreign (primarily Chinese, Korean and Japanese), who contributed to taxonomic, environmental and chorological studies of the genus Euonymus. The contributions of N.S. Turczaninow, K.J. Maksimovich, F.B. Schmidt, V.L. Komarov, T. Nakai, Ya.I. Prokhanov, A.I. Tolmachev, B.A. Shukhobodsky, T.G. Leonova, N.N. Tzvelev, S.K. Cherepanov, K.V. Kiseleva, V.A. Nedoluzhko to the formation of the modern taxonomic concept of the genus Euonymus are analyzed. Unresolved issues of biology of the Far Eastern species are emphasized, the ways of to solve them are outlined.
BIOLOGY OF THE EPIGEIC EARTHWORMS IN TROPICAL WET AND DRY CLIMATE OF DHARWAD (KARNATAKA), INDIA
Authors: And Pulikeshi M. Biradar Karuna S. Ganiger, Soumya R. Patil, Milind F. Nagannawar
Published: March 2022

Studies on biology of epigeic earthworms is very much necessary for the selection of suitable earthworm species in effective organic waste management through vermiculture and vermicomposting process for the production of quality and quantity worm biomass (vermiprotein) and vermicompost (biofertilizer). Hence, the present study was undertaken to study the biology of different epigeic earthworm species such as Eudrilus eugeniae (EE), Eisenia fetida (EF) and Perionyx excavatus (PE) cultured in cattle manure at tropical wet and dry climate of Dharwad district, Karnataka state, India. The results of the present study revealed that the incubation period or the time of emergence of juveniles from the cocoon was less (16.33±0.53 days) in Perionyx excavatus as compared to Eudrilus eugeniae (22.33±0.73 days) and Eisenia fetida (24.33±0.88 days). The percent hatching of cocoon was more in E. eugeniae (86.66±6.66) followed by E. fetida (73.33±5.33) and P. excavatus (66.66±4.66), whereas number of hatchling/cocoon was more in Eisenia fetida (2.66±0.33) followed by Eudrilus eugeniae (2.33±0.28) and less in Perionyx excavatus (1.33±0.23). The mean weight of juvenile (mg) at the time of hatching was more in EE (7.90±0.20) followed by EF (7.00±0.57) and less in PE (5.70±0.35). The attainment of sexual maturity was observed early during 6th -9th week in EF and PE, but it was late in EE during 7th -10th week and commencement of cocoon production was noticed soon after one or two week of maturity i.e. from 8th week onwards. It was continuous and multimodal in nature with slight decline in the growth rate after maturity and cocoon production in all three epigeic earthworm species (EE, EF and PE). The various life activities such as incubation period and number of hatchling, maturity were more in EF as that of EE and PE, whereas percent hatching and juvenile weight were more in EE followed by EF and PE. Therefore, the success of vermiculture and vermicomposting process for the production of quality and quantity worm biomass (vermiprotein) and vermicompost (biofertilizer) is mainly depends on the biology or life cycle of the epigeic earthworms, type of organic waste materials used and it also depends on the prevailing abiotic factors.
A CHECKLIST OF BIRDS AND DIVERSITY OF AVIAN FAUNA IN MUDASARLOVA RESERVOIR OF VISAKHAPATNAM, INDIA
Authors: Biswas Sanchari , Bhagyasree Venugopal , Rathod Vivek N.
Published: March 2022

The objective of this study was to enumerate a checklist of birds of the Mudasarlova Reservoir, which is man-made reservoir situated in the district of Visakhapatnam, Andhra Pradesh, India. It is used as a storage reservoir for drinking water and commercial purposes by the urban community. This area has always been blessed with diversity of flora, fauna (including avian fauna) since many years. The reservoir has also been a home and mating ground for various water birds, parakeets etc. It has also been a feeding and gliding ground for raptors. It is also accessed by the local community as a point of unsustainable fishing activities. But of late, this reservoir and the surrounding areas have been a witness to various developmental activities and simplification of natural landforms and the adjoining hills, due of urbanisation. As a result of this, the natural flow of the runoff water coming from various adjacent hills have been affected. This has not only triggered environmental and landform changes, but also has affected the avian fauna to certain extent.
DISTRIBUTION OF SHEATH-TAILED BATS (EMBALLONURIDAE) IN BUNDELKHAND REGION OF UTTAR PRADESH
Authors: And V. Elangovan Shaktivardhan Singh, Pawan Kumar Misra
Published: March 2022

The family Emballonuridae consist 54 species and distributed throughout the world. Six species of genus Taphazous were found in India. There was no proper report on distribution of Taphozous genus from Bundelkhand region. Therefore, an extensive survey was carried out in Bundelkhand region of Uttar Pradesh to explore the distribution of the genus Taphazous. A total of six roosts were recorded, which occupied by Taphazous species. Taphazous perforatus found only in Kulpahar Mahal, while rest five roosts were occupied by Taphazous nudiventris. T.nudiventris & T perforatus found in historical monuments made up of red stone, where the average roost height from the ground is 26.9 ± 3.78 (feet) and the average humidity and light intensity 56.2 ± 14.13 (%) and 1.4 ± 1.34 (lux) are respectively. The highest population was in Jhansi Palace (120 to 460 individuals), while lowest one was in Kalinjar fort (12 to 25 individuals). The roosts protected by Archaeological Survey of India. Due to human activity, the roosts were destroying day by day, by erection of nets at the entrance and light source on the roost. Therefore, need a proper conservation otherwise; there will be a great loss
FUMIGANT TOXICITY OF NATURAL PLANT PRODUCTS IN FORM OF ESSENTIAL OILS AGAINST PULSE BEETLE CALLOSOBRUCHUS CHINENSIS (L.) (COLEOPTERA:BRUCHIDAE)
Authors: Mishra Bhuwan Bhaskar
Published: March 2022

The cowpea weevil, Callosobruchus chinensis L. (Coleoptera: Bruchidae), is an important pest of stored cowpea, Vigna ungiculata (L.) Walpers (Fabales: Fabaceae), with ample distribution in tropical and subtropical regions. Many plant essential oils have a broad-spectrum activity against pest insects, and these oils traditionally have been used in the protection of stored products. The present investigation was aimed to assess the impact of two essential oils for their insecticidal activity against C. chinensis and they were tested in laboratory. In this study, the lethal and sub-lethal effects of essential oils from Aegle marmelos (L) Correa (Rutaceae) and Citrus reticulata (Rutaceae) were evaluated against the larvae and adults of C. chinensis at 30 ± 2° C, 75 ± 5% RH, and a photoperiod of 10:14 L:D. The LC50 values of A. marmelos and C. reticulata were 14.351 !IL and 15.231 !IL after 72 hr against adults and 13.296 [t.1_, and 14.997 1.11_, after 72 hr of exposure against larvae, respectively. Therefore, these essential oils can be suggested for controlling C. chinensis in storage systems.
MANAGEMENT RECOMMENDATIONS OF WILD BOAR IN SUB- TROPICAL CHIR PINE FOREST IN SIRAN FOREST DIVISION, TANGLAI RESERVE FOREST, DISTRICT MANSEHRA, KHYBER PAKHTUNKHWA
Authors: Thriq Khan, Shabbir Ahmed Jan,Dr. Bashirullahl Ahmed Zamir, Arz Muhammad Umranil,
Published: March 2022

The current study was conducted in May & June 2021 in Tanglai State Forest which is a Sub-Tropical Chir Pine Forest Type, the key species are: Common Leopard (Pathera Pardus), Wild Boar (Sus scrofa), Jackals (Canis aureus), Rhesus Monkey (Macaca Mulatta), Kalij Pheasant (Lophura leucomelanos), Flying Squirrels (Pteromyini). In KPK, Wild Boar is found mostly in the west of Indus around Peshawar, Mardan Bannu, D.I Khan etc. In this paper; it is recommended that the presence of Wild Boar and the way they may affect their habitat should be monitored because its population multiplies so fastly having high reproduction potential i.e. reaching sexual maturity as early as six (06) months of age, therefore, it is required to be managed in the habitats, the aim of such control should be to bring Wild Boar population into balance on particularly sensitive sites or in response to disease control. Moreover, this work is also aimed to suggest wild boar management to the authorized department, these approaches of management will be profitable to mitigate its adverse damages to the agricultural crops, forest crops, human beings, livestock i.e. wildlife conflicts.
Experience with open lavsanoplasty of the tibial collateral ligament
Authors:   Derzhavin Tambov State University, Medical Institute, Tambov, the Russian Federation, Yamshchikov O.N. ,   Kotovsk City Clinical Hospital, Kotovsk, the Russian Federation, Emelyanov S.A. ,   Derzhavin Tambov State University, Medical Institute, Tambov, the Russian Federation,   Kotovsk City Clinical Hospital, Kotovsk, the Russian Federation, Mordovin S.A. ,   Derzhavin Tambov State University, Medical Institute, Tambov, the Russian Federation,   Kotovsk City Clinical Hospital, Kotovsk, the Russian Federation, Kolobova E.A. ,   Derzhavin Tambov State University, Medical Institute, Tambov, the Russian Federation
Published: March 2022

Introduction The tibial collateral ligament (TCL) is one of the major ligaments of the knee and designed to counteract valgus forces. Tibial collateral ligament injury can be treated conservatively with prolonged immobilization and limited weight-bearing on the injured limb. Clinical experience and a high complication rate after conservative treatment indicate the need for surgical intervention to restore the integrity of the TCL. The purpose is to demonstrate a successful management of a patient with ruptured TCL of the right knee joint and substantiate the priority of surgical treatment in the case. Material and methods A clinical case is reported and a brief literature analysis on the topic provided. The experience with open lavsanoplasty used for a patient with rupture of the TCL resulting from dislocated tibia is presented. The effectiveness of treatment was assessed radiologically and physically for the limb functionality and ROM in the knee joint. Results and discussion Open lavsanoplasty performed for the TCL injury resulted in complete restoration of the limb function and anatomical integrity of the ligament. The good result persisted after the removal of the metal construct. The method allowed us to avoid complications being typical for conservative treatment: medial instability of the knee joint and deforming arthritis, and showed the advantages over other surgical treatments used to regain the integrity of the TCL. Conclusion Open lavsanoplasty of the TCL used as the patented technique facilitated complete recovery the injured limb, the functionality, less risk of complications providing a good clinical result.
Results of the second toe autotransplantation for thumb reconstruction
Authors:   Bashkir State Medical University, Ufa, Russia, Minasov B.Sh. , Garapov I.Z. ,   Bashkir State Medical University, Ufa, Russia, Biktasheva E.M. ,   Bashkir State Medical University, Ufa, Russian Federation, Valeev M.M. ,   Bashkir State Medical University, Ufa, Russian Federation, Iakupov R.R. ,   Bashkir State Medical University, Ufa, Russian Federation, Minasov T.B. ,   Bashkir State Medical University, Ufa, Russian Federation, Mavliutov T.R. ,   Bashkir State Medical University, Ufa, Russian Federation
Published: March 2022

Defects of the thumb negatively impact physical and mental health, lead to depression, inferiority complex and hopelessness in the future. The aim of the study was to explore long-term results of thumb reconstruction using autologous transplantation of the second toe with microvascular anastomoses. Material and methods Second toe transplantation for thumb reconstruction was performed for 54 patients. There were 48 male and 6 female patients aged from 12 to 55 years. When analyzing the long-term results of surgical treatment of patients. The anatomy and functionality of the repaired finger was evaluated at a long term measuring the range of motion in the joints, muscle strength of the hand and major types of hand grips. Results The autograft completely healed with opposition of the reconstructed thumb and the rest fingers restored in 51 patients. The autograft failed in three cases treated with less functional methods. Conclusion Microsurgical reconstruction technologies used for a lost thumb facilitated rapid recovery of the finger and significantly improved functions of the injured hand as an entity. Free second toe transplantation using microvascular anastomoses for the thumb reconstruction allowed the patient regain basic gripping functions and improve cosmesis of the injured hand.
Caracterización de la sociedad civil contemporánea
Authors: Sánchez Jiménez Wilson , Montes Moreno José Ferney
Published: March 2022

Las acepciones de la sociedad civil son disímiles y encontradas en muchos aspectos, sobre todo si se tiene en cuenta su relación con el Estado y con los monopolios económicos (Marx y Engels, 1975). La noción de sociedad civil ha venido tomando fuerza en los distintos ámbitos del pensamiento político, filosófico y social, situación que no se presentaba con la misma intensidad en épocas anteriores. Sin embargo, a raíz de tal difusión de lo que se entiende por sociedad civil, se intentará hacer un esbozo, así sea muy generalizado, de algunas concepciones recientes sobre dicha cuestión.
The Use of Data Mining and Automated Social Networking Tools in Virtual Learning Environments to Improve Student Engagement in Higher Education
Authors:   Lincoln College, UK, Smith Stephen , Cobham David , Jacques Kevin
Published: March 2022

Virtual learning environments (VLEs) form part of modern pedagogy in education; they contain student usage data that has the potential to inform and improve this pedagogy. The question this paper explores is how might the development of data mining and log analysis systems for the Moodle virtual learning environment improve students’ course engagement? The paper proposes that a student will complete missed tasks sooner if their utilisation of the VLE is automatically tracked and electronic prompts are sent when VLE activities are missed. To explore and test the hypothesis a software tool, MooTwit was developed to contact students when they fell behind in their VLE study. To establish if student timely engagement improved the study used MooTwit with two groups of students over a period of 15 weeks, messaging one group only when they fell behind. Statistical analysis and comparisons were made between how quickly each group engaged with the missed items. Using MooTwit to track and contact students did influence the timeliness of their engagement with the VLE activities. Specifically, the results suggest by direct messaging a student to engage with missed material, they completed missed activities closer to required completion date. The findings within the thesis show that educational data mining has the potential to improve pedagogy in VLE linked education offering opportunities to increase timely engagement and to raise course designers’ acceptance of data mining to improve the validity and quality of course evaluation.
Adapting e-Learning for Japanese EFL Students
Authors:   the Foreign Language Department, Institute of Liberal Arts, Kyushu Institute of Technology, 1-1 Tobata-ku, Kitakyushu-city, Japan, Long III Robert W. , Watanabe Hiroaki
Published: March 2022

This study examined the effect e-learning had on second-year Japanese university English as a Foreign Language (EFL) student Test of English for International Communication (TOEIC) scores, which is a standardized English test. The English language learner e-learning system was developed by Gyuto-e ASP and had 800 multiple-choice listening questions. The four research questions were focused on the following: the possible differences in the TOEIC scores between the students who had completed the online module and those who had not; the possible score differences between genders; and whether any students had completed the e-learning but had not had any significant increases in their TOEIC scores. It was found that all tests were statistically non-significant at a 5% level. Further research is to be conducted on improving the e-learning program usage so that it has a more direct and meaningful effect on the students’ test scores.
ICARE Approach for Designing Online Learning Module Based on LMS
Authors:   Universitas Pendidikan Ganesha, Bali, Indonesia, Suartama I Kadek , Mahadewi Luh Putu Putrini , Divayana Dewa Gede Hendra , Yunus Muhammad
Published: March 2022

Online learning started with the emergence of internet technology and has been increasingly used during the COVID-19 pandemic. However, it has raised many problems, such as limitations in presenting material (monotonous and uninteresting), building activeness and difficulty creating interaction between lecturers and students and between students. Moreover, online learning is more stressful than regular classroom sessions because students have to study alone. The absence of clearly structured learning steps also makes it difficult for them to focus. Therefore, this research aims to develop an independent online learning module with a structured and systematic flow called Introduce, Connect, Apply, Reflect and Extend (ICARE) based on the Learning Management System. Furthermore, it determines the eligibility of the module using a Research and Development (R&D) for Education design involving Analysis, Design, Development, Implementation and Evaluation. All stages resulted in an eligible online module with an LMS-based ICARE flow in the Learning Media course.
Factors Affecting Academic Achievement in SW Education
Authors:   the Information Systems Department, Hanyang University, Seoul, Korea, Cheon Minjong , Lee Ook , Mun Changbae , Ha Hyodong
Published: March 2022

Software industry is becoming the core of technology trend. SW-based changes in education, industry, and social perception are continuously increasing, and thus, computing power is recognized as an essential requirement in higher education. Globally, research on software (SW) education methodology is being actively conducted, and from this point of view, the socio-economic importance of software education is increasing. This study conducted a study on how to identify the educational characteristics and motivations of students. In this study, a method to deal with the motivation for SW education from the perspective of student characteristics was reviewed. For this analysis, the relationship between educational achievement and factors is analyzed, and factors that can affect student achievement are explored. Factors for the methodology are identified and verified with a statistical methodology.
Student-Generated Videos Using Green Screen Technology in a Biology Class
Authors:   the Palawan State University, Philippines, Blacer-Bacolod Donnalyn
Published: March 2022

This study explores the effectiveness, learning benefits, and positive and negative experiences of using student-generated videos as an approach to project-based learning in a biology class. Ninety-two Grade 11 students were chosen through matched pairing of characteristics and had participated in this mixed-method research. Students in the experimental group made video projects using the Green Screen by Do Ink application. The effectiveness of the intervention was determined through posttest assessments of the experimental and comparison groups. A postexposure self-report survey was also administered to understand the learning benefits and experiences of the students who made the video projects. The results of this initial study show that the student-generated video project has statistical and practical effects in the study of animal physiology lessons. Its utilization significantly improved the students’ test scores. Likewise, they appreciate the cognitive, technical, and life skill contributions of using it, although there are minimal demotivating experiences. This study contributes to the literature in student-generated video and project-based blended learning.
Research on the Talents Education Scheme Based on Integration of Science and Education for Information and Communication Engineering
Authors:   Harbin Institute of Technology, Harbin, China, Yin Zhendong , Wu Zhilu , Li Dasen , Zhao Yaqin , Liu Jinlong
Published: March 2022

Information and Communication Engineering is the forefront of science and technology competition among major countries in the world, which is characterized by rapid updating of knowledge system, extensive cross-cutting of scientific research directions and high requirements on the innovation ability of talents. This paper puts forward the mode of cultivating graduate innovative talents in information and communication engineering subject, which combines morality and talent, science and education. Guided by the spirit of scientists, to carry out ideological and political education in an all-round and multidimensional way, the training mode aims to comprehensively enhance the motivation of graduate students and aims to enhance the ideal and faith of serving and developing a powerful country through science and innovation, with high-level scientific research projects and innovative achievements as the guidance, the integration of science and education and multiple measures to cultivate graduate students' scientific research innovation practical ability. The practice shows that the moral education effect of the talent training mode proposed in this paper is remarkable, which greatly improves the motivation of study and enthusiasm for innovation of postgraduates and strengthens the ideal and faith of a strong country in science and technology. Moreover, the innovation ability of the graduate students has been significantly improved, and the graduate students have made great progress in systematic thinking, creative thinking and practical ability. Besides, they have made more high-level innovation achievements.
Dual Banking System Stability Index in the Shadow of COVID-19 Pandemic
Authors: Yunita Patria
Published: March 2022

The financial system is categorized as stable if there is no excessive volatility from financial pressures or crises. The IMF indicates that the crisis is not only related to one element but more than two or three elements of the crisis. The banking system's stability is measured by the banking stability index, gauging the effectiveness of monetary policy and financial risk. This study aims to measure the stability of the Indonesian banking system in the dual banking system model. The indicator to measure banking stability used the Z-score statistic based on fluctuations of Return on Assets for each type of bank. The Markov Switching Vector Autoregressive (MSVAR) model method was used to analyze the volatility of banking stability. Independent variables used included credit risk (NPL), Loan to Deposit Ratio, Liquidity Risk, Net Interest Margin, Capital Adequacy Ratio, Money Market Rate, Inflation, Gross Domestic Product, Federal Reserve rate, and Exchange Rate. The results of the regime switch analysis concluded that Indonesia's banking stability experienced a structural break due to the effects of the pandemic in April 2020. Based on the average Z-score value, the Islamic banking stability index was higher than conventional banking. In other words, Islamic banking was more stable than the conventional banking system. The Islamic banking stability index (iZscore) was significantly influenced by the level of Net Operating Margin, Financing to deposit ratio, Potential Loss Profit Sharing, Islamic Money Market Rate, and Exchange Rate. However, non-performing financing did not affect Islamic banking stability since the profit-sharing system implemented by Islamic banking stability was more influenced by the ratio of potential loss and profit-sharing system.
Raktasaaf home grown ayurvedic medication as blood purifier
Authors: Samani Kamrudeen , Shrestha Surya Krishna
Published: March 2022

Blood is a connective tissue that defends us against a range of infections. The body cannot survive without blood, yet blood does not purify itself. When the blood does not purify itself, the kidneys, liver, and lymphatic system work together to assist in the purification of the blood. Modern living, bad food, drink, and other factors all contribute to blood pollutants. When blood gets impure, it produces a variety of issues such as acne, rashes, allergic reactions, and so on. It is beneficial in purifying the blood while also protecting it from other issues. For blood contaminants, there is no suitable synthetic treatment. The blood purifier is only made with herbal formulas. In this review article, we reviewed market formulations and the various plants that are utilized in them, as well as their various actions that aid in blood purification and protection from other issues
Analysis of histopathological pattern of thyroid lesions in a tertiary care hospital
Authors: Mahadani Jayawant , Turkey Huzefa Ali
Published: March 2022

Thyroid gland is unique in having a wide spectrum of disorders and these thyroid disorders are common worldwide. However, the thyroid gland lesions vary in their incidence and histopathological patterns. Hence the present study was undertaken to determine thehistopathological pattern of thyroid lesions in Tertiary Care Centre.

Total 80 thyroidectomy specimens received in the Pathology Department during a period from January 2018 to December 2019 were included in the study. Detailed information regarding age, gender, clinical status, relevant investigations like fine needle aspiration cytology, thyroid scan, ultrasound reports and operation findings were obtained from histopathology request forms and register. Percentages and simple frequency tables were used for data analysis.

Out of 80 thyroidectomy specimens, 64 (80%) were from females and 16 (20%) were from males. The age of patients ranged from 21 to 73 years with a mean age of 43.05±13.55 years. 67 cases (83.75%) were non-neoplastic and 13 cases (16.25%) were neoplastic. The most common non-neoplastic lesions were colloid goiter (36 cases; 45%) followed by multi-nodular goiter (10 cases; 12.5%) whereas most common neoplastic lesions were follicular adenoma (8 cases, 10%) and papillary carcinoma (3; 3.75%).

The histopathological evaluation of thyroid lesions is challenging and mandatory as the diagnosis varies from non-neoplastic to rare neoplastic lesions. In the present study, non-neoplastic thyroid lesions were more common than neoplastic ones with female predominance. Most common non-neoplastic lesions were colloid goiter while most common neoplastic lesions were follicular adenoma.
Fibroepithelial polyp (Acrochordon) of breast nipple– A rare clinical presentation
Authors: Banga Vineet , Jain Stuti
Published: March 2022

Fibroepithelial polyp (FEP) or acrochordon are skin tags frequently arising in skin folds in locations like the neck, axilla, perineum, eyelids and chest wall. Only 7 cases of FEP of the nipple have been reported in the literature so far. Here we report such a rare case diagnosed on FNAC and Biopsy.
Osseous metaplasia in multiple broad ligament leiomyomas: An extreme rarity
Authors: Saxena Rajeev , Agarwal Nidhi , Tasneem Rangwala , Buliwal Deeksha
Published: March 2022

Osseous metaplasia in a leiomyoma is an uncommon clinical entity with the presence of mature and immature bone in a leiomyoma. Infection, necrosis, hyaline degeneration, calcification and myxoid degeneration are the most common secondary degenerative changes seen in cases of leiomyoma. Calcified and ossified leiomyomas are uncommon and is rarely reported in literature. We report one such case in a 45 year old perimenopausal female who presented clinically with abnormal uterine bleeding. Multiple nodules were seen in bilateral broad ligaments, which on histopathology revealed features of osseous metaplasia in hyalinized degenerated leiomyomas, an extremely rare clinical entity.
The Gender Gap in Public S&T Funding: The Matilda Effect in STEM Disciplines in Argentina
Authors: Fiorentin Florencia , Pereira Mariano , Suárez Diana
Published: March 2022

This study explores the presence of gender bias in public grants for science and technology (S&T) activities known as the Matilda effect in STEM disciplines (science, technology, engineering, and mathematics) in Argentina. The empirical analysis is based on the Scientific and Technological Research Projects program (PICT in Spanish) for the period 20032015 and found that female researchers are less likely to be awarded the first time they apply for a research grant than their male counterparts (-6.2 percentage points, or p.p.). Even for follow-on applications after the first one, without having been awarded before, female researchers remain less likely to be awarded (-3.8 p.p.). However, the probability of being recurrently awarded known as the Matthew effect is the same for both male and female researchers. This paper concludes that female researchers in STEM suffer disadvantages in the allocation of public funds to finance their research projects. Only those female researchers that overcome the initial barriers and obtain their first grant can take advantage, as their male counterparts do, of the Matthew effect that makes them more likely to obtain further awards. These results suggest the need for policies aiming at reducing the initial gender gap in accessing public grants for female researchers in STEM.
Numerical Solution for Electronic Assemblies Subjected to Mechanical Bending
Authors: Gharaibeh Mohammad A. , Almohammad Aseel A.
Published: March 2022

This work introduces high-accuracy numerical solution for the two elastically coupled beams subjected to mechanical bending problem. Finite difference method (FDM) was considered to solve the governing equations along with the boundary conditions of the structure. The validity of this solution was ensured and tested with literature data. Finally, the influence of the key structural parameters of the problem, such as the relative stiffness between the beams as well as the elastic layer, was thoroughly discussed with the specific attention on its application in electronic assemblies subjected to mechanical bending. The numerical findings showed that for stiffer beams and compliant layer, the axial deformations of the layer are lower which can be reflected as lower solder stresses and hence more reliable designs of electronic devices.
Development of New Admittance Matrix for Newton-Raphson Power Flow in Distribution Networks
Authors: Alzaareer Khaled , Salem Qusay , El-Bayeh Claude Ziad , Harasis Salman , Aldaoudeyeh Al-Motasem I. , Malkawi Ahmad M.A. , Al-Shetwi Ali Q.
Published: March 2022

Network modelling is a critical step in the analysis of distribution networks. It is used to relate the input currents and voltages with the output currents and voltages. This work aims to construct a new admittance matrix for distribution networks. The new admittance matrix is derived based on ABCD matrix, which presents the exact model of different types of power distribution networks considering the unbalance/balanced and single/three phase characteristics. The model takes into account shunt admittances to reflect the accurate performances of the components in the distribution networks, especially in the presence of distributed generation units. The importance of considering shunt admittance is due to the presence of capacitive charging current which can affect the node voltages. Application of the new admittance matrix of distribution networks in Newton-Raphson power flow analysis is performed. The standard IEEE 37 bus system is used to test the validity of the proposed approach. MATLAB environment is used to confirm the results. Simulation results show the accuracy of new network admittance matrix in power flow analysis.
Targeting Angiogenesis in Cancer Treatments: Where do we Stand?
Authors: Petrovic Nenad
Published: March 2022

Since early seventies of the twentieth century, through seminal work of Judah Folkman, angiogenesis, the process of new blood vessel sprouting from the existing vasculature, was recognized as a necessary part of wound healing, development of placenta, tissue growth and regeneration as well as cancer progression. This process is induced by low tissue oxygenation and it is a crucial prerequisite for rapid tissue growth, providing proper oxygen supply and removal of toxic metabolites. Suppression of angiogenesis as a way of slowing down tumor progression continues to be one of the most important areas of cancer research. The angiogenic process is relatively complex and it is regulated by numerous pro- and anti-angiogenic factors. Intensive research in the last twenty years resulted in identification of more than 300 angiogenesis inhibitors, a trend that is expected to continue. Unfortunately, most of these treatments have demonstrated unacceptable toxicities or failed to show activity in clinical studies. Although not yet completely understood, the complex process of tumor angiogenesis involves highly regulated orchestration of multiple activating and inhibiting factors. Vascular endothelial growth factor (VEGF) and its cognate receptors appear to play a central role in angiogenesis activation. Thus, initial efforts to develop anti-angiogenic treatments focused largely on inhibiting VEGF action. Such approaches, however, often lead to transient responses due to multiple pathways able to compensate for a single pathway inhibited. Accordingly, more recent treatments have focused on simultaneous inhibition of multiple signaling pathways. This review concentrates on identifying those anti-angiogenic treatments that made to the clinic by receiving approval by USA Food and Drug Administration (FDA) as treatments for cancer. Regardless of observed problems, it is an imperative that research in angiogenesis regulation continues. Consequently, pharmacological manipulation of angiogenesis may yet to introduce truly new pharmacological therapies into the field of cancer therapy, the field that was rather dormant in the last several decades. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
The laws of the synergetic effects emergence in Russian economy
Authors:   Saratov State University, Porezanova Elena V.
Published: March 2022

Introduction. Modern economy is dynamic and consists of various actions of business entities that can lead to the emergence of synergetic effects. There are patterns that gradually turn into laws of the synergetic effects occurrence. To analyze and systematize these laws is an important research task. This is the relevance of the research topic. Theoretical analysis. There are several aspects of the emergence and functioning of synergetic effects: the time trend, the criteria of optimality and positivity. The analysis of synergetic effects according to the optimality criterion is of special interest. The initial, desirable, pre-optimal and optimal synergism are highlighted. The types of suboptimal synergism: nonsinergism, desinergism, resinergism and antisysinergism are revealed using historical and logical approach at the micro and macro levels. Results. Dynamic and static laws of synergetics are revealed. The internal and external factors of the optimal and non-optimal synergetic effects occurrence are identified, taking into account the action of the synergetics laws.
The dialogue about the new economic policy: J. M. Keynes and V. I. Ulyanov-Lenin
Authors:   Saratov State University, Cheremisinov Georgy A.
Published: March 2022

Introduction. It is particularly interesting to study the achievements of outstanding personalities on the world scale, those who made a significant contribution to economic science, played a crucial role in the international history of politics and economic activity, laid the prerequisites for the formation of original schools of economic thought, which were named after their founders. Such personalities were John Maynard Keynes and Vladimir Ilyich Ulyanov-Lenin. Methods and concepts. The term “dialogue”, meaning a conversation, an exchange of statements in spoken and written speech, precisely characterizes the format of correspondence communication between J. M. Keynes and V. I. Lenin. Having no personal acquaintance with each other, no mutual sympathies, the interlocutors addressed each other in publications and public speeches, setting out and commenting on the words and thoughts, deeds and actions, moral values, social and political ideals shared by the vis-a-vis. The dialogue between the two prominent persons dealt with the problems of developing and implementing a new economic policy in the international sphere and in certain countries. Analysis and interpretation. The immediate reason for the beginning of the dialogue was the publication of J. M. Keynes’ book “Economic Consequences of Peace” in December 1919, which repeatedly mentioned the name of V. I. Lenin. The dialogue of J. M. Keynes and V. I. Lenin took place not only in the format of publicly addressing each other, indicating the name of the interlocutor, but also in a hidden form of reminiscence – memories of what was said and heard, written and perceived by the counterpart. Results. The communication between J. M. Keynes and V. I. Lenin was maintained in the “Ab voce, ad rem” mode – from words to deeds. Serious thoughts expressed by the interlocutors found their real embodiment.
Conceptual foundations of the Western communicative theory of law: Nicholas Luhmann
Authors:   Saratov State University, Tikhonova Sophia V.
Published: March 2022

Introduction. The article deals with the theory of law by Nicholas Luhmann as one of the most important conceptual and methodological sources of Western communicative theories of law developed in the context of post-metaphysical thinking in social theory. Theoretical analysis. In the social system of Luhmann, communication communicates, so the concept of Luhmann belongs to the number of non-subjective ones. The legal system in this concept is formed by the differentiation of communications, thanks to which a legal co de arises. On its basis, specific communications are redefined, being included in the legal system. The function of the legal subsystem is to stabilize other subsystems by normalizing the expectations of counterparties and “monitoring” all subsystems. Empirical analysis. Luhmann shows that the justification of law within law is impossible due to the paradox of self-application – law cannot determine whether it is itself a law. The logical paradoxicity of law does not cancel its functionality, since the basis of law is transcendent and is brought into the political system. Results. The Luhmann model of autopoiesis is not correlated with usnaturalism, since it is focused on the processes of social self-organization. It reflects the classical explanatory schemes traditional for legal positivism, since positivization is ultimately subordinated to the transcendent political basis of law.
Legal education as constitutional value: Problems of forming the student’s legal culture
Authors:   Saratov State University, Torosyan Rima A. , Basova Alla V. ,   V. I. Razumovsky Saratov State Medical University
Published: March 2022

Introduction. The specifics of modern professional legal education are inherently linked with the need to form the legal culture of a lawyer, which is an important constitutional value. The fundamental paramount role of legal education as a constitutional value is traced not only in the course of formation of sense of justice and the legal culture of future lawyers, but also indirectly, through realization of a professional component: law-making, law-enforcement, law-enforcement activity. In this regard, the formation of the professional legal culture of students in legal education is one of the most important aspects of their studies, and is a prerequisite for the effective implementation of national law in their subsequent professional activities. Theoretical analysis. The authors made an attempt to comprehensively study the factors that influence the process of forming the professional competencies of future lawyers, in particular their moral orientation, necessary to serve “law.” Empirical analysis. We analyzed the professional competencies that determine the demand for graduates of legal universities on the labor market and are regulated by the Federal Law "On education in the Russian Federation", as well as requirements for lawyers specified by employers. Results. The authors conclude that a carefully organized legal education system can be effective only when the legal culture of a lawyer is brought up and formed while training students, with a responsible attitude to the duty to serve the law and the interests of society.