bluuebunny/crossref_metadata_2025 huggingface dataset:
Model Test and Numerical Analysis on the Deformation and Stability of a Landslide Subjected to Reservoir Filling
Authors: Hu Xinli , He Chuncan , Zhou Chang , Xu Chu , Zhang Han , Wang Qiang , Wu Shuangshuang
Published: July 2019

Reservoir filling can affect the landslide stability and cause the landslide deformation within the reservoir area. In this paper, a physical model test and a series of numerical analyses were combined to investigate the landslide deformation and stability under reservoir filling. The surface deformation, deep displacement, and pore water pressure were recorded during the physical model test. In the model test, the increasing period of the pore water pressure inside the landslide is proposed to be a critical period for the landslide subjected to the reservoir filling. During this period, large landslide deformation occurred. The numerical analyses show that a greater factor of safety (FOS) appeared under a higher water level rising rate or a lower permeability coefficient during the water level rising stage when other variables are fixed, due to the domination of the reservoir buttressing effect which can increase the landslide resistance. During the reservoir maintaining stage, the reservoir water infiltrated into the landslide continuously to cause the matric suction dissipation and pore water pressure increase, which reduced the landslide shear strength and then decreased the landslide stability.
Seismic Fragility Analysis of Steel Liquid Storage Tanks Using Earthquake Ground Motions Recorded in Korea
Authors: Lee Sangmok , Kim Byungmin , Lee Young-Joo
Published: July 2019

Liquid‐containing storage tanks are important structures in industrial complexes. Because earthquake damages to liquid storage tanks can cause structural collapse, fires, and hazardous material leaks, there have been continuous efforts to mitigate earthquake damages using seismic fragility analysis. In this regard, this study focuses on the seismic responses and fragility of liquid storage tanks. First, the characteristics of earthquake ground motions are a critical factor influencing the seismic fragility of structures; thus, this study employs real earthquake records observed in the target area, southeastern Korea, with the earthquake characteristics estimated based on the ratio of peak ground acceleration to peak ground velocity. When a liquid storage tank oscillates during an earthquake, additional forces can impact the tank wall owing to hydrodynamic pressures. Therefore, this study presents a sophisticated finite element (FE) model that reflects the hydrodynamic effect of an oscillating liquid. Another advantage of such an FE model is that detailed structural responses of the entire wall shells can be estimated; this is not possible in simplified lumped mass or surrogate models. Lastly, probabilistic seismic demand models are derived for three critical limit states: elastic buckling, elephant’s foot buckling, and steel yielding. Using the real earthquake ground motion records, constructed FE model, and limit states, a seismic fragility analysis is performed for a typical anchored steel liquid storage tank in Korea. In addition, for comparison purposes, a ring‐stiffened model is investigated to derive a seismic fragility curve. The results of the seismic fragility assessment show that elastic buckling is the most vulnerable damage state. In contrast, elephant’s foot buckling and steel yielding indicate relatively severe damage levels. Furthermore, it is observed that ring stiffeners decrease the elastic buckling damage, although there is no practical effect on elephant’s foot buckling and steel yielding in all ground motion intensities.
Kangai Injection, a Traditional Chinese Medicine, Improves Efficacy and Reduces Toxicity of Chemotherapy in Advanced Colorectal Cancer Patients: A Systematic Review and Meta-Analysis
Authors: Huang Siqi , Peng Weijun , Mao Dan , Zhang Shaofan , Xu PanPan , Yi PengJi , Zhang Sifang
Published: July 2019

Objective. To systematically review whether the Kangai injection (KAI), which is commonly used traditional Chinese medicine, can improve the clinical efficacy of chemotherapy and relieve adverse reactions of chemotherapy in advanced colorectal cancer (CRC) patients. Methods. A comprehensive literature search was performed in three English and three Chinese electronic databases until March 2019. The literature was screened by EndNote X8 and data were analysed by RevMan5 and Stata12.0. Results. This meta-analysis consisted of twenty-eight studies, of which 2310 cases were reported. Among the 2310 cases, 1207 cases were treated with KAI combined with chemotherapy and 1103 cases were treated with chemotherapy alone. The results showed that KAI combined with chemotherapy significantly improved tumor response (Risk Ratio (RR) =1.32; 95% confidence interval (CI): 1.22-1.43; p<0.00001); Karnofsky performance status (KPS score) (Risk Ratio (RR) =1.48; 95% CI: 1.36-1.60; p<0.00001); reduced adverse drug reactions (ADRs) such as nausea and vomiting (OR =0.31; 95% CI: 0.24-0.41; p <0.00001), diarrhea (OR =0.36; 95% CI: 0.25-0.52; p<0.00001), leukopenia (OR =2.97; 95% CI:2.27-3.88; p<0.00001), thrombocytopenia (OR =0.53; 95% CI: 0.38-0.74; p<0.0002), liver dysfunction (OR =0.29; 95% CI: 0.20-0.44; p<0.00001), neurotoxicity (OR =0.51; 95% CI: 0.36-0.71; p = 0.0004); increased immune function (CD3+: MD=6.34; 95% CI: 5.52-7.16; p < 0.00001, CD4+: MD=-5.99; 95% CI: 5.20-6.78; p < 0.00001; and CD4+/CD8+: MD=0.34; 95% CI: 0.14-0.54; p < 0.0009), and prolonged survival time (OR =1.77; 95% CI: 1.25-2.50; p = 0.001). Renal dysfunction caused by chemotherapy was not affected by KAI treatment (Odds Ratio (OR) =0.53; 95%IC: 0.25-1.12; p = 0.10). Conclusion. KAI can increase clinical effectiveness, improve quality of life, alleviate ADRs, and prolong survival time in advanced colorectal (CRC) patients receiving chemotherapy.
Prevalence of Overweight and Obesity among Libyan Men and Women
Authors: Lemamsha H. , Randhawa G. , Papadopoulos C.
Published: July 2019

Libya is following the trend observed in developing countries of steadily becoming more obese, such that obesity in Libya has reached epidemic proportions in the twenty-first century. The prevalence of obesity in Libya has more than doubled in the last three decades, with the numbers of overweight and obese adults being continuing to grow. Therefore, this study aimed to estimate and describe the prevalence of overweight and obesity among Libyan men and women. A cross-sectional survey was conducted to examine the prevalence of overweight and obesity among the Libyan population. A multistage sampling technique was employed to select 401 Libyan adults randomly from the Benghazi electoral register. Qualified nurses were allocated to take anthropometric measurements (including visceral fat and Body Mass Index (BMI)) from participants using the Segmental Body Composition Analyser and a portable Stadiometer. The response rate achieved in this cross-sectional study was 78%. Four hundred and one Libyan adult, aged 20-65 years, participated; 253 were female (63%). The prevalence of obesity, overweight, and normal weight among Libyan adults was 42.4%, 32.9%, and 24.7%, respectively. The results also revealed that approximately 75.3% of Libyan adults were overweight and obese, and the prevalence of overweight and obesity in women was significantly higher than that in men (the prevalence of overweight was 33.2% in women compared to 32.4% in men, while the prevalence of obesity was 47.4% in women compared to 33.8% in men, respectively). The findings of this study confirmed that obesity and overweight are the fastest growing issues and have become one of the most serious public health challenges confronting the Libyan authorities. As the obesity epidemic in Libya continues to escalate, with a complete absence of prevention interventions to reduce obesity, more research is desperately needed to follow the trend of gender difference in the prevalence of overweight and obesity among Libyans adults across the Libyan state to improve the effective interventions for preventing obesity.
In SilicoPhylogenetic and Structural Analyses of Plant Endogenous Danger Signaling Molecules upon Stress
Authors: Pavlopoulou Athanasia , Karaca Ezgi , Balestrazzi Alma , Georgakilas Alexandros G.
Published: July 2019

The plant innate immune system has two major branches, the pathogen-triggered immunity and the effector-triggered immunity (ETI). The effectors are molecules released by plant attackers to evade host immunity. In addition to the foreign intruders, plants possess endogenous instigators produced in response to general cellular injury termed as damage-associated molecular patterns (DAMPs). In plants, DAMPs or alarmins are released by damaged, stressed, or dying cells following abiotic stress such as radiation, oxidative and drought stresses. In turn, a cascade of downstream signaling events is initiated leading to the upregulation of defense or response-related genes. In the present study, we have investigated more thoroughly the conservation status of the molecular mechanisms implicated in the danger signaling primarily in plants. Towards this direction, we have performedin silicophylogenetic and structural analyses of the associated biomolecules in taxonomically diverse plant species. On the basis of our results, the defense mechanisms appear to be largely conserved within the plant kingdom. Of note, the sequence and/or function of several components of these mechanisms was found to be conserved in animals, as well. At the same time, the molecules involved in plant defense were found to form a dense protein-protein interaction (PPi) network, suggesting a crosstalk between the various defense mechanisms to a variety of stresses, like oxidative stress.
Analyzing Some Structural Properties of Topological B-Algebras
Authors: Gonzaga Narciso C.
Published: July 2019

In this study, we investigate the topology on B-algebras: an algebraic system of propositional logic. We define here the notion of topological B-algebras (briefly, TB-algebras) and some properties are investigated. A characterization of TB-algebras based on neighborhoods is provided. We also provide a filterbase that generates a unique B-topology, making a TB-algebra in which the filterbase is a neighborhood base of the constant element, provided that the given B-algebra is commutative. Finally, we investigate subalgebras of TB-algebras and introduce the notion of quotient TB-algebras of the given B-algebra.
The Use of Portal Vein Pulsatility to Differentiate Hypervolemic and Hypovolemic Hyponatremia
Authors: Singh Gurkeerat , Rachoin Jean-Sebastien , Chien Christina , Patel Sharad
Published: July 2019

Hypotonic hyponatremia is a common electrolyte disorder defined by a blood serum sodium value of less than 136 meq/L. A challenge in managing hyponatremia is accurately determining the etiology for the free water excess as management can markedly differ. Accurate diagnosis of the etiology of hypotonic hyponatremia requires precision in the determination of extracellular volume status. Determination of volume status has traditionally relied on physical examination, imaging modalities, and clinical gestalt, all of which are inaccurate. Portal vein pulsatility is an easy to perform bedside ultrasound imaging study which can be used as a marker for hypervolemia and venous congestion. We present 2 cases of hypervolemic hyponatremia in which portal vein pulsatility was used in the diagnosis and management and as a marker for efficacy of treatment.
Bayesian Network Approach to Customer Requirements to Customized Product Model
Authors: Yang Qin , Li Zhirui , Jiao Haisen , Zhang Zufang , Chang Weijie , Wei Daozhu
Published: July 2019

Customizing products based on customer needs is an irreversible trend, and many companies strive to provide customized products to customers in less time. Customer requirements are a key factor in the company's ability to provide customized products. In order to better meet customer needs, solve the problem of incomplete and inaccurate expression, and improve the correlation between customized product performance and customer demand, a customized product method based on Bayesian network is proposed. First, the company built a custom product model based on Bayesian networks. According to the model, the customer selects some nodes and their related information. Then, we can accurately predict the final product model through the link tree algorithm, test the customer demand node to determine the focus of the customer's needs, and optimize the model. Finally, an example of a multifunctional nursing bed is used to illustrate the effectiveness of the method.
The Emerging Role of YAP/TAZ in Tumor Immunity
Authors: Pan Zhaoji , Tian Yiqing , Cao Chengsong , Niu Guoping
Published: July 2019

Yes-associated protein (YAP)/WW domain-containing transcription regulator 1 (TAZ) is an important transcriptional regulator and effector of the Hippo signaling pathway that has emerged as a critical determinant of malignancy in many human tumors. YAP/TAZ expression regulates the cross-talk between immune cells and tumor cells in the tumor microenvironment through its influence on T cells, myeloid-derived suppressor cells, and macrophages. However, the mechanisms underlying these effects are poorly understood. An improved understanding of the role of YAP/TAZ in tumor immunity is essential for exploring innovative tumor treatments and making further breakthroughs in antitumor immunotherapy. This review primarily focuses on the role of YAP/TAZ in immune cells, their interactions with tumor cells, and how this impacts on tumorigenesis, progression, and therapy resistance.
The Use of Simple Laboratory Parameters in the Differential Diagnosis of Acute-Phase Zika and Dengue Viruses
Authors: Musso Didier , Nhan Tu-Xuan , de Pina Jean-Jacques , Marchi Joffrey  , Texier Gaëtan
Published: July 2019

Background: Differential diagnosis between acute-phase Zika and dengue is challenging because of a similar clinical presentation and the lack of available molecular diagnosis tools in most of endemic areas. Objectives: Our study aimed to evaluate the use of simple laboratory parameters to differentiate these infections. Methods: We retrospectively compared simple hematology and biochemistry values in 81 and 341 patients with confirmed Zika and dengue, respectively, collected from June 2013 to March 2014 during the French Polynesia outbreaks. Results: Thrombocytopenia, neutropenia, leukopenia, lymphopenia, and elevated aspartate aminotransaminases were significantly more frequent in dengue than in Zika (p < 0.001). Platelets <100 × 109/L, neutrophils <0.5 × 109/L, lymphocytes <0.5 × 109/L, and aspartate aminotransaminases >100 IU/mL were found in dengue but not in Zika. The positive predictive value of the ­association of leukocytes <4 × 109/L + lymphocytes <1 × 109/L + aspartate aminotransaminases >40 IU/mL for the diagnosis of dengue was 90%, with an accuracy of 82.4%. Conclusion: For the differential diagnosis between acute-phase Zika and dengue, there is no specific standard laboratory pattern. We identified cutoff values and a combination of laboratory parameters that are a strong argument against Zika and in favor of dengue.
Pediatric to Adult Transition in Sickle Cell Disease: Survey Results from Young Adult Patients
Authors: Travis Kate , Wood Anthony , Yeh Peter , Allahabadi Sachin , Chien Ling-Chen , Curtis Sara , Hammond Allexa , Kohn Jaden , Ogugbuaja Christine , Rees Matthew , Shumway John , Sheehan Vivien
Published: July 2019

Background/Aims: We surveyed sickle cell disease (SCD) patients who transitioned from pediatric care at Texas Children’s Hematology Center (TCHC) to adult care to determine the characteristics of patients with an adult SCD provider, continuation rates of pre-transition therapies, and patient perceptions of the transition process. Methods: A cross-sectional study was conducted by telephone survey of 44 young adults with SCD, aged 19–29 years, who transitioned from TCHC to adult care within the last 15 years. Results: Findings of the 23-item questionnaire revealed that transitioned patients with current adult providers (68.2%) were more likely to have seen a provider within 6 months of transition (p = 0.023) and to have been on hydroxyurea and/or monthly blood transfusions pre-transition (p = 0.021) than transitioned patients without a provider; 83% of patients on pre-transition hydroxyurea reported continuing hydroxyurea after transition. Transition challenges included inadequate preparation, difficulty finding knowledgeable adult providers, and lack of healthcare insurance/coverage. Conclusion: Transition to adult providers is predicted by establishing care with an adult SCD provider within 6 months of transition and being on pre-transition disease-modifying therapy. Transition may be improved if pediatric hematology centers assist and verify adult provider contact within 6 months of transition and engage patients of all disease severity during transition.
Percent Consonant Correct as an Outcome Measure for Cleft Speech in an Intervention Study
Authors: Sell Debbie , Sweeney Triona
Published: July 2019

Background/Aims: Percent consonant correct (PCC) was originally described by Shriberg and Kwiatkowski [J Speech Hear Disord. 1982 Aug;47(3):256–70] as a severity metric for phonological speech disorders, and has been adapted and used in many studies on speech sound disorders. It is well-recognized that cleft speech is complex, consisting of several interacting parameters assessed simultaneously, with error sounds not in the listener’s own language. In speech outcome studies, narrow phonetic transcription and the reporting of intra- and inter-rater reliability are acknowledged as the gold standard. However, cleft speech brings special challenges to this task, as complex speech disorders are known to be associated with low transcriber agreement. Recent studies informed the decision to use PCC as the primary outcome measure in a cleft speech intervention study, given its common usage and familiarity. The aim was to specifically evaluate the intra- and inter-rater reliability of PCC in an intervention study, in contrast to other types of speech outcome studies. Methods: Two trained and experienced listeners analyzed 119 recordings, randomly selected from five data points before, during, and following intervention. The PCC score was separately calculated for words and sentences/phrases. Results: Using intraclass correlations (ICCs), Phase 1 results showed poor reliability for targets elicited for words (ICC = 0.07) and sentences/phrases (ICC = 0.42). Differences in classification of errors as glottal stops and consonant deletion accounted for this. Following further training, a second reliability study was undertaken showing improvement in the number of targets elicited in words (ICC = 0.85) and sentences/phrases (ICC = 0.94). There was very good inter-rater reliability for the PCC score on the word dataset (ICC = 0.9) and the sentence dataset (ICC = 0.88). Very good intra-rater reliability (ICC = 1.0) was found for the PCC score in both words and sentences/phrases for each listener. One listener consistently gave higher modified PCC scores. Conclusions: In cleft speech intervention studies, reliability of the number of targets elicited should be reported. Listeners need to distinguish between glottal articulation and consonant deletion, in order that the PCC score is meaningful. Attention should be paid to where listeners are reliable, but their pattern of scores consistently differs but in a consistent way. More research is needed on measuring the resolution of articulation difficulties in cleft intervention studies.
Fluoride in Saliva and Oral Mucosa after Brushing with 1,450 or 5,000 ppm Fluoride Toothpaste
Authors: Staun Larsen Line , Baelum Vibeke , Richards Alan , Nyvad Bente
Published: July 2019

The aim was to measure and compare fluoride concentrations in oral mucosa and saliva following a single brushing with either 1,450 or 5,000 ppm fluoride toothpaste. Fourteen healthy participants provided saliva and oral mucosa samples in the morning before tooth brushing. Then participants brushed their teeth with 1,450 ppm fluoride toothpaste, and saliva and mucosa samples were collected after 1, 2, 4, and 6 h. The experiment was repeated 3–7 days later with 5,000 ppm fluoride toothpaste. All samples were analyzed for fluoride using an ion-selective electrode adapted for microanalysis. Pre-brushing fluoride concentrations were higher in mucosa (mean1,450 0.26 ppm and mean5,000 0.20 ppm) than in saliva (mean1,450 0.08 ppm and mean5,000 0.07 ppm). The mean fluoride concentrations increased in both mucosa and saliva following a single brushing with both 1,450 ppm (meanmuc1,450 (1 h) 1.15 ppm, meansal1,450 (1 h) 0.33 ppm) and 5,000 ppm fluoride toothpaste (meanmuc5,000 (1 h) 3.21 ppm and meansal5,000 (1 h) 0.90 ppm). At 6 h, the fluoride concentrations had returned to pre-brushing levels. Across the 6-h sampling period the fluoride concentration in saliva was statistically significantly 1.4 times higher following brushing with 5,000 ppm compared with 1,450 ppm fluoride toothpaste. For mucosa, this ratio was only 1.1 and not statistically significant. In conclusion, the fluoride level in oral buccal mucosa is higher than in saliva and follows the same fluoride clearance pattern as in saliva. Over the initial 6-h period following a single tooth brushing, the ratio of the fluoride concentration in mucosa to that in saliva is independent of the fluoride concentrations in the toothpastes used.
Fatores do absenteísmo em primeira consulta num ambulatório de oncologia em um Hospital Universitário
Authors: Mazza Túlio de Oliveira , Ferreira Gabriela Souza Assis , Picoli Renato Mantelli , Costa André Lucirton
Published: July 2019

Introdução: o absenteísmo dos usuários de sistemas de saúde representa um grande problema para as organizações. O objetivo deste estudo foi identificar as razões para o absenteísmo dos pacientes em consulta médicas. Metodologia: pesquisa de campo nos ambulatórios de oncologia do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto. Os pacientes que não compareceram à primeira consulta em 2013 (356) foram contatados por meio telefônico, dos quais 299 não foi possível o contato por apresentarem telefone inválido, desligado, fora da área de cobertura ou por não atenderem a ligação. Resultados: 57 pacientes foram entrevistados e apontaram os motivos para falta. As respostas foram categorizadas. Os resultados mostraram que 27 pacientes (47%) não compareceram à consulta por motivos relacionados ao indivíduo ou comportamento, sendo “consultei-me em outro lugar” o mais recorrente (12,30%), seguido de “consulta coincidiu com outro compromisso” (7,02%) e “não me lembro o motivo” (7,02%). Individualmente, o motivo mais citado pelos pacientes foi “eu não faltei a consulta” (31,6%), o que sugere problemas de comunicação. Conclusão: as principais razões para o absenteísmo estão relacionadas ao indivíduo e que problemas de cadastro do paciente e comunicação dificultam a compreensão das causas do absenteísmo.
Lipidomics, Atrial Conduction, and Body Mass Index
Authors: Del Greco M Fabiola , Foco Luisa , Teumer Alexander , Verweij Niek , Paglia Giuseppe , Meraviglia Viviana , Melotti Roberto , Vukovic Vladimir , Rauhe Werner , Joshi Peter K. , Demirkan Ayse , Felix Stephan B. , Pietzner Maik , Said M. Abdullah , van de Vegte Yordi J. , van der Harst Pim ,   Lifelines Cohort Study*, Wright Alan F. , Hicks Andrew A. , Campbell Harry , Dörr Marcus , Snieder Harold , Wilson James F. , Pramstaller Peter P. , Rossini Alessandra , Pattaro Cristian
Published: July 2019

Background:

Lipids are increasingly involved in cardiovascular risk prediction as potential proarrhythmic influencers. However, knowledge is limited about the specific mechanisms connecting lipid alterations with atrial conduction.

Methods:

To shed light on this issue, we conducted a broad assessment of 151 sphingo- and phospholipids, measured using mass spectrometry, for association with atrial conduction, measured by P wave duration (PWD) from standard electrocardiograms, in the MICROS study (Microisolates in South Tyrol) (n=839). Causal pathways involving lipidomics, body mass index (BMI), and PWD were assessed using 2-sample Mendelian randomization analyses based on published genome-wide association studies of lipidomics (n=4034) and BMI (n=734 481), and genetic association analysis of PWD in 5 population-based studies (n=24 236).

Results:

We identified an association with relative phosphatidylcholine 38:3 (%PC 38:3) concentration, which was replicated in the ORCADES (Orkney Complex Disease Study; n=951), with a pooled association across studies of 2.59 (95% CI, 1.3–3.9;
P
=1.1×10
−4
) ms PWD per mol% increase. While being independent of cholesterol, triglycerides, and glucose levels, the %PC 38:3-PWD association was mediated by BMI. Results supported a causal effect of BMI on both PWD (
P
=8.3×10
−5
) and %PC 38:3 (
P
=0.014).

Conclusions:

Increased %PC 38:3 levels are consistently associated with longer PWD, partly because of the confounding effect of BMI. The causal effect of BMI on PWD reinforces evidence of BMI’s involvement into atrial electrical activity.
Procedural and Anatomical Determinants of Multielectrode Renal Denervation Efficacy
Authors: Tzafriri Abraham R. , Mahfoud Felix , Keating John H. , Spognardi Anna-Maria , Markham Peter M. , Wong Gee , Highsmith Debby , O’Fallon Patrick , Fuimaono Kristine , Edelman Elazer R.
Published: July 2019

Radiofrequency renal denervation is under investigation for treatment of hypertension with variable success. We developed preclinical models to examine the dependence of ablation biomarkers on renal denervation treatment parameters and anatomic variables. One hundred twenty-nine porcine renal arteries were denervated with an irrigated radiofrequency catheter with multiple helically arrayed electrodes. Nerve effects and ablation geometries at 7 days were characterized histomorphometrically and correlated with associated renal norepinephrine levels. Norepinephrine exhibited a threshold dependence on the percentage of affected nerves across the range of treatment durations (30–60 s) and power set points (6–20 W). For 15 W/30 s treatments, norepinephrine reduction and percentage of affected nerves tracked with number of electrode treatments, confirming additive effects of helically staggered ablations. Threshold effects were only attained when ≥4 electrodes were powered. Histomorphometry and computational modeling both illustrated that radiofrequency treatments directed at large neighboring veins resulted in subaverage ablation areas and, therefore, contributed suboptimally to efficacy. Account for measured nerve distribution patterns and the annular geometry of the artery revealed that, regardless of treatment variables, total ablation area and circumferential coverage were the prime determinants of renal denervation efficacy, with increased efficacy at smaller diameters.
Patterns and Outcomes of Endovascular Therapy in Mild Stroke
Authors: Asdaghi Negar , Yavagal Dileep R. , Wang Kefeng , Mueller-Kronast Nils , Bhatt Nirav , Gardener Hannah E. , Gutierrez Carolina M. , Marulanda-Londoño Erika , Koch Sebastian , Dong Chuanhui , Oluwole Sophia A. , Hanel Ricardo , Mehta Brijesh , Robichaux Mary , Nobo Ulises , Zevallos Juan C. , Rundek Tatjana , Sacco Ralph L. , Romano Jose G.
Published: July 2019

Background and Purpose—

We aimed to evaluate the current practice patterns, safety and outcomes of patients who receive endovascular therapy (EVT) having mild neurological symptoms.

Methods—

From Jan 2010 to Jan 2018, 127,794 ischemic stroke patients were enrolled in the Florida-Puerto Rico Stroke Registry. Patients presenting within 24 hours of symptoms who received EVT were classified into mild (National Institutes of Health Stroke Scale [NIHSS] ≤5) or moderate/severe (NIHSS>5) categories. Differences in clinical characteristics and outcomes were evaluated using multivariable logistic regression.

Results—

Among 4110 EVT patients (median age, 73 [interquartile range=20] years; 50% women), 446 (11%) had NIHSS ≤5. Compared with NIHSS >5, those with NIHSS ≤5 arrived later to the hospital (median, 138 versus 101 minutes), were less likely to receive intravenous alteplase (30% versus 43%), had a longer door-to-puncture time (median, 167 versus 115 minutes) and more likely treated in South Florida (64% versus 53%). In multivariable analysis younger age, private insurance (versus Medicare), history of hypertension, prior independent ambulation and hospital size were independent characteristics associated with NIHSS ≤5. Among EVT patients with NIHSS ≤5, 76% were discharged home/rehabilitation and 64% were able to ambulate independently at discharge as compared with 53% and 32% of patients with NIHSS >5. Symptomatic intracerebral hemorrhage occurred in 4% of mild stroke EVT patients and 6.4% in those with NIHSS >5.

Conclusions—

Despite lack of evidence-based recommendations, 11% of patients receiving EVT in clinical practice have mild neurological presentations. Individual, hospital and geographic disparities are observed among endovascularly treated patients based on the severity of clinical symptoms. Our data suggest safety and overall favorable outcomes for EVT patients with mild stroke.
Salsola strobilifera (Chenopodiaceae), a new combination for a remarkable Australian taxon
Authors: MOSYAKIN SERGEI L.
Published: July 2019

The new combination Salsola strobilifera is proposed for the morphologically remarkable Australian taxon originally described by Bentham as S. kali var. strobilifera (basionym). The latter name is lectotypified on a specimen from K (barcode K000899590) that was collected in New South Wales by Beckler during the Burke and Wills Victoria Exploring Expedition of 1860–1861, and was studied by Bentham for his Flora Australiensis. Earlier taxonomic treatments and other studies of “strobiliferous” native Australian plants (having short ovoid to almost globular strobile-like terminal inflorescences which are easily broken off at maturity) are briefly discussed and summarized. Judging from available morphological and partly molecular evidence, there are at least two “strobiliferous” morphotypes in Australia, one probably more closely related to S. australis sensu stricto and another more similar to S. sabrinae (= S. tragus subsp. grandiflora). It is concluded that Salsola sensu stricto is represented in Australia and adjacent islands by several (four or five, probably more) rather distinct native taxa that should be better recognized as separate species. On the basis of their morphological distinctiveness, these taxa are comparable to many other currently recognized Eurasian ones. The presence of Eurasian alien species also cannot be excluded. The need for a comprehensive study of Australian taxa of Salsola is emphasized.
Caroxylon camphorosma, a new combination for Salsola camphorosma (S. camphorosmoides Iljin, nom. illeg., non Desf.) (Chenopodiaceae)
Authors: MOSYAKIN SERGEI L.
Published: July 2019

Recent molecular phylogenetic, morphological and anatomical studies (e.g., Akhani et al. 2007, Wen et al. 2010, Voznesenskaya et al. 2013, Schüssler et al. 2017) resulted in recognition of several monophyletic genera instead of the phylogenetically unnatural Salsola Linnaeus (1753: 222) sensu lato. In particular, the taxonomic resurrection of the genus Caroxylon Thunberg (1782: 37) prophetically proposed by Tzvelev (1993, see also Tzvelev 1996, 2012) was convincingly confirmed by molecular evidence (Akhani et al. 2007, Wen et al. 2010, Feodorova 2011, 2012, Feodorova & Samigullin 2014, Schüssler et al. 2017, and references therein); see also taxonomic and nomenclatural overviews and updates (e.g., Mosyakin et al. 2017, Mucina 2017). The taxonomic recognition of Caroxylon and other segregate genera resulted in numerous nomenclatural changes, in particular, transfers of taxa from Salsola sensu lato to other currently accepted genera (see e.g., Akhani et al. 2007, Feodorova 2011, 2015, Falatoury et al. 2017, Mucina 2017). However, it appears that not all currently recognized taxa originally described in Salsola have been properly transferred to Caroxylon. One interesting nomenclatural case is considered here.
Discovery, dispersal, and genetic diversity of Rhyacophila lobifera Betten, 1934 (Trichoptera: Rhyacophilidae) in southeast Michigan, USA

Authors: FUSARO ABIGAIL J. , McCULLOCH BRUCE , PETRELLA SALLY , WILLIS VELON
Published: July 2019

Rhyacophila lobifera Betten, 1934 has been previously documented in the upper Midwest states of Ohio, Indiana, and Illinois, and the province of Ontario. Here we report on the diversity of this species in the Rouge and Huron River watersheds using DNA barcode-verified identifications to confirm the first known Michigan record of this species, with collection from the lower Rouge River in 2003 and again in 2008. Since first detection, we document that the range of R. lobifera in the Rouge River watershed has expanded to include at least one additional site on the Lower Branch and five sites on the Middle Branch (Johnson Creek), as well three sites in the neighboring Huron River watershed. Our sequence analysis of the mitochondrial COI barcode gene region suggests a fine scale population structure in these watersheds, with haplotype partitioning congruent with proposed dispersal patterns based on first records at each site. Ranking as a 4 on the Hilsenhoff's biotic index—an intermediate level of water quality tolerance, discovery of R. lobifera in an urbanized southeast Michigan watershed is not unexpected, but population genetic patterns lend insight into its recent range expansion.
The genus Kisaura (Philopotamidae) in Shikoku, western Japan, with descriptions of three new species

Authors: KUHARA NAOTOSHI
Published: July 2019

Kisaura collections from Shikoku, western Japan were examined and 8 species including 3 new species were recognized: K. ashizuriensis sp. nov., K. curvispina sp. nov. K. brevis sp. nov. K. kisoensis (Tsuda), K. minakawai Arefina, K. tsudai (Botoşǎneanu), K. nozakii (Kuhara) and K. dichotoma Kuhara & Arefina. Males of all 3 new species are described. Kisaura imparis Hur & Morse is synonymized under K. minakawai.
Trichoptera of Liaoning Province, People’s Republic of China
Authors: MORSE JOHN C. , LI JING-KE , SUN CHANG-HAI , ZHANG XUE-PING , LIN LIN , GAO MEI-XIANG
Published: July 2019

The caddisfly fauna of Liaoning Province, in northeastern China, is one of the least known Trichoptera faunas in the People’s Republic of China, with only 21 species (and 1 subspecies) of the 1253 Chinese species reported previously from this Province. A recent collection from Mt. Laopingding, Fencheng City, included 13 species, at least 9 of which are new species records for the Province, 3 are new species records for Palearctic China, and 2 others are new records for China. The species belong to 7 genera and 5 families which were not previously known from Liaoning. Variations in the male genitalia of Hydropsyche orientalis Martynov, 1934 and H. simulans Mosely, 1942 are discussed.
Three new species of genus Chimarra Stephens, 1829 (Trichoptera: Philopotamidae) from Indian Himalaya

Authors: PANDHER MANPREET SINGH , PAREY SAJAD H.
Published: July 2019

Three new species are added to the philopotamid fauna of India. The newly described species under the genus Chimarra Stephens include C. kanchenjungaensis sp. nov. and C. golitarensis sp. nov. both from Sikkim and C. kamengensis sp. nov. from Arunachal Pradesh. With these additions the number of species from India now becomes 48. This increase is attributed to the rich diversity of genus Chimarra from Himalayan region based on the male genitalia. These species are distinguishable from each other, as well as from the previously known allied species, by consistent taxonomic features of the inferior appendages, tergite X and the phallic apparatus of males.
Rhyacophila dandaganu, a new caddisfly from the southern Cumberland Plateau (USA) (Trichoptera: Rhyacophilidae)

Authors: ROBINSON JASON L. , PARKER CHARLES R.
Published: July 2019

We describe a new species in the caddisfly genus Rhyacophila (Trichoptera: Rhyacophilidae) from the southern Cumberland Plateau of the United States.  Rhyacophila dandaganu n. sp. is placed in the Rhyacophila lobifera Group from North America, the second known species in this group.  The new species is distinguished from Rhyacophila lobifera Betten, 1934 by the shape and dimensions of several genitalic structures, as well as the absence of parameres accompanying the endotheca and the characteristic shape of the tenth segment and phallicata.  We discuss the geographic range of these two species and the questions raised by the curious (apparent) lack of sympatric populations.  We discuss some testable hypotheses that might determine how populations of R. dandaganu n. sp. and R. lobifera could maintain phenotypic distinctiveness, in the absence of obvious geographic barriers to gene flow, including behavioral, chemical or tactile mating cues.
OBITUARY: Eric Paul McElravy, November 28, 1946-August 27, 2014
Authors: RESH VINCENT H.
Published: July 2019

Eric P. McElravy, an active researcher in Trichoptera and other groups of aquatic insects for 4 decades, died in San Leandro, California, on August 27, 2014. He was born on November 28, 1946, and raised in Ohio. He completed a Bachelor of Science and a Master of Science degree at Kent State University, and then spent 10 years as a high school science teacher before earning a Doctor of Philosophy degree in Entomology from the University of California, Berkeley. Following this, Eric worked as an environmental consultant on various projects throughout California.
Behavioral response of adult caddisflies (Trichoptera) to blue and green light-emitting diode lamps
Authors: KIMURA GORO , TAJIKA GORO , KUSAMA TOSHIHIRO , TANIKAWA TSUTOMU
Published: July 2019

To clarify the effect of the visible spectrum, we collected Trichoptera adults using blue, green, and white light-emitting diode (LED) lamps and black light (BL) lamps. Except for white LED lamps, all lamps emitted broad-band wavelengths in the ultraviolet spectrum. A total of 212 adult Trichoptera were trapped. The most individuals were attracted by BL (96), followed blue (74), green (32), and white (10). Hydroptilidae spp. was the most abundant taxa among the lamps (183 individuals, 86.3%), followed by Cheumatopsyche brevilineata (23 individuals, 10.8%). Only Hydroptilidae spp. was common to all lamps. The Shannon–Wiener diversity index (H’) was highest at 0.96 for BL, followed by green (0.53), and blue (0.28). Trichoptera were attracted to both UV light and visible light. These results suggest that BL is the most useful for faunistic investigations of Trichoptera.
Two new species of Trevathana (Crustacea, Cirripedia, Balanomorpha, Pyrgomatidae) from the Western Indian Ocean and French Polynesia
Authors: ACHITUV YAIR , LANGZAM YAAKOV
Published: July 2019

Two new species of the Pyrgomatid barnacle Trevathana are described: Trevathana synthesysae nov. sp., extracted from Plesiastrea versipora from the Indian Ocean Islands Réunion and Mauritius, and Trevathana isfae nov. sp. from a colony of Favia stelligera from French Polynesia, which, until recently, was terra incognita with regard to coral-inhabiting barnacles. The two new species are distinctive by their relatively broad scutum as compared to Trevathana dentatum, their prominent adductor ridge extending beyond the basal margin of the scutum, and their quadrangular tergum.
Notes on the Papua New Guinea genus Cheronella Miller (Hemiptera: Reduviidae: Reduviinae), with a redescription of its little known type species
Authors: ZHAO PING , CONSTANT JEROME , CAI WANZHI
Published: July 2019

The monotypic Papua New Guinea genus Cheronella Miller is reexamined. The diagnostic characters of the genus are modified and its little known type species, Cheronella stuberi Miller, 1955, is redescribed. The characters of male genitalia are reported for the first time. The dorsal habitus, head, male genitalia, and other diagnostic morphological features are illustrated.
Cis pickeri sp. nov. (Coleoptera: Ciidae) from Southern Africa
Authors: LOPES-ANDRADE CRISTIANO , MATUSHKINA NATALIA , BUDER GERDA , KLASS KLAUS-DIETER
Published: July 2019

A new species of ciid beetle from southwestern South Africa is described. Images of the habitus, male genitalia and other characters of the external morphology are provided. The observed variations of male secondary sexual characters are briefly discussed. The similarities of external morphological characters of Cis pickeri sp. nov. to other species of Cis Latreille are discussed, and the new species is tentatively included in the bilamellatus species group.
A new Dinapsis species from the Central African Republic (Hymenoptera, Megalyridae, Dinapsini)
Authors: SHAW SCOTT RICHARD , VAN NOORT SIMON
Published: July 2019

A new species of megalyrid wasp, Dinapsis centralis Shaw and van Noort sp. nov. from the Central African Republic is described and illustrated. The new species is contrasted with other described species of Dinapsis. An online key to Dinapsis species is available at: http://www.waspweb.org/Megalyroidea/Megalyridae/Keys/index.htm. This represents the first record of any megalyrid species from the Central African Republic and the northernmost confirmed distribution of Dinapsis in the Afrotropical region. The taxonomic history, distribution, biogeography and biology of Megalyridae are discussed.
Recognizing diversity in blennioid fish nomenclature (Teleostei: Blennioidei)
Authors: HASTINGS PHILIP A. , SPRINGER VICTOR G.
Published: July 2019

Species inventories for macroecology, biogeography and conservation biology rely upon accurate lists of valid species. In order to provide a more uniform taxonomic treatment for blennioid fishes, we evaluated the taxonomic status of 21 species with currently recognized subspecies. In six cases we found no compelling evidence for recognizing these nominal forms as distinct species. However, in 15 cases, evidence exists for elevating 17 subspecies to full species status based on currently used criteria for delimiting fish species. This evidence includes the existence of significant phenotypic and/or genetic differences supporting the hypothesis that they are on distinct evolutionary pathways in accordance with a phylogenetic species concept. Known distributions of affected species are modified accordingly. Most of these elevated species are separated from their closest relatives by well-known biogeographic barriers.
The genus Leptodora Lilljeborg (Crustacea: Branchiopoda: Cladocera) is not monotypic: description of a new species from the Amur River basin (Far East of Russia)
Authors: KOROVCHINSKY NIKOLAI M.
Published: July 2019

New species, Leptodora richardi sp. nov., is described from some large lakes and other water bodies of the Lower Amur River basin. It differs from L. kindtii Focke, the only species known in this genus until now, by a smaller body size and proportions of some body parts, namely a comparatively longer head and shorter abdomen, and by presence of fine setules on the end of anterior distal seta of second segment of thoracic limbs of first pair. Small differences in male features require further elucidation. Among the investigated populations of L. kindtii, one of them from the Volga Delta was analyzed in more detail due to the unusually small size of their adults, comparable with those of L. richardi sp. nov., but had body proportions characteristic of the former species and probably represented its extreme morpho-ecological variation. L. kindtii is widely distributed in Palearctic, while L. richardi sp. nov. seems to be an endemic of East Asia probably distributed from the Lower Amur River in the Far East of Russia to Eastern China and Japan (Honshu Island) in the south.
Checklist of helminth parasites of threatened vertebrate species from Brazil
Authors: MUNIZ-PEREIRA LUÍS C. , VIEIRA FABIANO M. , LUQUE JOSÉ L.
Published: July 2019

Using available records, unpublished information retrieved from the Helminthological Collection of the Oswaldo Cruz Institute (CHIOC) and published reports, a checklist of the recorded helminth parasites of endangered vertebrates from Brazil was generated. A total of 772 records and 186 helminth species (6 Acanthocephala, 83 Nematoda, 23 Cestoda, 64 Trematoda, 10 Monogenea) in 76 host species (7 Actinopterygii, 8 Chondrichthyes, 1 Amphibia, 10 Reptilia, 22 Aves, 28 Mammalia) from Brazil were listed in the present work, including 39 undetermined helminth species and 10 new host records. This is the first compilation of the helminth parasites of threatened vertebrates in Brazil and in the Neotropics.
Tardigrades of the Seychelles Islands, with the description of three new species
Authors: PILATO GIOVANNI , LISI OSCAR
Published: July 2019

In the context of the project “The Nature Protection Trust of Seychelles”, three species new to science are described (Macrobiotus creber sp. n., Macrobiotus perfidus sp. n. and Macrobiotus diguensis sp. n.) and two species (Macrobiotus madegassus and Minibiotus continuus) are recorded for the Seychelles for the first time. Macrobiotus creber sp. n. belongs to the furciger group but it differs from the members of this group in some metric characters of the buccopharyngeal apparatus, or of the claws, and in some characters of the eggs. Macrobiotus perfidus sp. n. is similar to M. pseudocoronatus but it differs from it in having small cuticular tubercles, in lacking an anterior band of teeth and a less developed posterior ring of triangular teeth in the buccal cavity, in having slightly shorter macroplacoids, slightly longer and slender claws and in characters of the eggs. Macrobiotus diguensis sp. n. is similar to M. snaresensis and M. erminiae but it differs from them in metric characters of the bucco-pharyngeal apparatus, in having more slender claws and in some characters of the eggs.
A taxonomic study of the Indian species of Euops Schoenherr (Coleoptera: Curculionoidea: Attelabidae)
Authors: RIEDEL ALEXANDER
Published: July 2019

The Euops species of India excluding the Himalaya region are revised. Seven species are recorded from the area, placed in three subgenera (Parasynaptopsis Legalov, 2003 stat. n., Flavoriedeliops Legalov, 2003 stat. n. and Riedeliops Alonso-Zarazaga & Lyal, 2002) as follows: E. (Parasynaptopsis) andrewesi Voss, 1935, E. (Flavoriedeliops) tamilnadunsis Legalov (2003), E. (Riedeliops) bowringii Jekel, 1860, E. (Riedeliops) indicus (Legalov, 2004), E. (Riedeliops) keiseri Voss, 1957, E. (Riedeliops) pseudoindicus sp. n. and E. (Riedeliops) trichinopoliensis (Legalov, 2007). Diagnoses are provided for the subgenera E. (Parasynaptopsis) and E. (Flavoriedeliops) and a description for E. (Riedeliops). The genera Asynaptops Legalov, 2007, Nigroeuops Legalov, 2003, Orienteuops Legalov, 2003 and Sawadaeuops Legalov, 2003 are downgraded to subgenera and synonymised with E. (Riedeliops) (syn. n.), as are the subgenera Asynaptopsis Legalov, 2007 and Orienteuopsidius Legalov, 2008 (syn. n.), while the genera Indoeuops Legalov, 2007, Morphoeuops Legalov, 2003 are synonymised with E. (Parasynaptopsis) (syn. n.). Euops bowringii Jekel, 1860, E. indicus (Legalov, 2004) comb. n., E. keiseri Voss, 1957, E. rasuwanus (Legalov, 2003) comb. n. and E. trichinopoliensis (Legalov 2007) comb. n. are transferred to E. (Riedeliops) and E. andrewesi Voss, 1935 to E. (Parasynaptopsis) (new placements). The following new synonymies are proposed: Euops andrewesi Voss, 1935 (= E. ammattiensis (Legalov, 2007) syn. n.); Euops bowringii Jekel, 1860 (= E. armipes Voss, 1933 syn. n., E. submetallicus Voss, 1935, syn. n., Asynaptops (Asynaptopsis) colombensis Legalov, 2007, syn. n.); Euops (Riedeliops) rasuwanus (Legalov), 2003 ( = Parasynaptops bengalensis Legalov, 2007, syn. n.). Lectotypes are designated for the names E. andrewesi, E. bowringii, E. armipes and E. submetallicus. One new species, E. pseudoindicus sp. n., and one new subspecies, E. keiseri nilgiriensis ssp. n., are proposed. All species are described or redescribed in detail, primary types and relevant characters are illustrated, a key to the species is provided and the distributions of the species are mapped.