bluuebunny/crossref_metadata_2025 huggingface dataset:
Perception and Practices on Transmission of Vector Borne Diseases among Rural People
Authors: Mosleh Uddin Abu Noman Mohammed
Published: May 2022

Introduction: Vector-borne diseases are illnesses transmitted by arthropods or invertebrates and caused by different microorganisms in human. These diseases accounts for almost 20% of the diseases and disability suffered globally. More than 50% the global population at present projected to be at risk of diseases transmitted by arthropod or invertebrate vectors. Knowledge on the existing perception and practices on transmission of vector borne diseases among rural community would be beneficial to provide a need-based health care delivery system to them.
Objective: To know about the perception and practices regarding vector borne diseases in rural community.
Materials and Methods: This observational type of crosssectional study was conducted by non-probability purposive sampling method in 474 respondents of Dhamrai and Saturia Upazila from August 2019 to February 2020. Data were analyzed by using Microsoft office packages and calculator and presented in the form of tabulation and diagrams.
Results: Findings of this study showed that 76% respondents were Muslims and 35% respondents were above 50 years old. Among 474 respondents, 88% and 78% stated mosquitos and houseflies as vectors responsible for transmitting various diseases, after that 35% Itch mite, 34% Louse and 42% Sandflies. Respectively 72% and 85% respondents stated Malaria and Dengue is transmitted by arthropod vectors, followed by 54% Chikungunya, 35% Kala azar, 13% Filariasis and 33% Typhoid fever. Though, 64%, 67%, 86% and 22% respondents stated bite of mosquito as mode of transmission of malaria, chikungunya, dengue and filariasis correspondingly. In particular, 95%, 87%, 1% and 17% respondents stated personal protection measures, removal of water collection, fogging and spraying as the control measures for mosquito and other vector associated diseases respectively. However, 91%, 74% and 78% respondents used mosquito net, mosquito coil and screening of windows as their frequently used methods for preventing vector borne diseases.
Conclusion: Knowledge about arthropod vectors and vector borne diseases at rural level requires improvement. A fair percent of respondents having satisfactory information regarding the name of arthropod vector and illnesses transmitted by them, their mode of transmission in addition to distinct control measures for the prevention of vector borne diseases. Community oriented health education modules should be adopted by the government to boom the knowledge of the village people concerning name of precise vectors and the sicknesses transmitted by means of them.
JAFMC Bangladesh. Vol 17, No 2 (December) 2021: 33-38
Efficacy of Rupatadine in Treatment of Chronic Idiopathic Urticaria
Authors: Ahmed Moyassaque , Latif Khan Abdul , Alam Md Shakibul , Wahab Md Abdul
Published: May 2022

Introduction: Urticaria is a vascular lesion of the skin characterized by the appearance of well demarcated wheels along with angioedema. In more than 75% of cases, a causative agent can’t be established and thus is termed as chronic Idiopathic Urticaria. Treatment of this condition focuses on measures which provide symptomatic relief; 2nd and 3rd generation anti-histaminic drugs are the mainstays now for the treatment of chronic idiopathic urticaria.
Objectives: To determine the efficacy of rupatadine in the treatment of chronic idiopathic urticaria.
Materials and Methods: A clinical trial was conducted on 60 patients who were suffering from chronic idiopathic urticaria from March to August 2015 at Department of Dermatology and Venereology, Combined Military Hospital (CMH), Dhaka. Tab. Rupatadine 5 mg 1 tab daily was given for 6 weeks. Clinical response of treatment and adverse effect was assessed at every two weeks’ interval by taking history and clinical examination. Ethical issue was addressed
Results: The patients reported a considerable improvement in overall chronic idiopathic urticaria due to the use of Rupatadine. The mean total symptom score (TSS) value reduced by 83% compared to the base line evaluation at the end of the therapy duration. Total disappearance of symptom was recorded in 25% patients. There were 79% decrease in the score for number of wheals, 81% reduction in the score for size of the wheals, 88% reduction in the pruritus severity score, and 83% reduction in the duration of pruritus score in relation to baseline evaluation.
Conclusion: 5mg of Rupatadine once daily is effective in patients with chronic idiopathic urticaria.
JAFMC Bangladesh. Vol 17, No 2 (December) 2021: 39-42
Magnetic Resonance Image Findings in Radicular Low Back Pain
Authors: Umar Muhammad , Zoherul Alam Syed , Rahim Zamil Zaidur , Rahman Mohammad Saifur , Akhter Nahid
Published: May 2022

Introduction: Low back pain (LBP) is the most common symptom associated with degenerative disc disease. Common causes of radicular low back pain are narrowing of the space where nerve roots exit the spine, which can be result of stenosis or disc herniation. Magnetic Resonance Imaging (MRI) is the key investigation for diagnosis of radicular LBP. Objective: To find the association between radicular low back pain and MRI findings of degenerative disc disease. Materials & Methods: This cross-sectional study was conducted in the Combined Military Hospital (CMH), Dhaka, from January to June 2018. A total of 128 patients with LBP with or without radiculopathy were included in the study. Lumbosacral MRI was carried out in all patients.
Results: One third (34.4%) of the patients had LBP with radiculopathy. A substantial proportion (68%) of patients had history of trauma to back-bone. Majority (97.7%) of the patients had disc degeneration. Approximately 72% had nerve-root compression and over three-quarters (76.6%) had spinal canal stenosis. Radiculopathy was significantly associated with past history of trauma to the back-bone (p < 0.01) and history of loadbearing (p < 0.001). Signs of degenerative disease were evident as Modic changes in 80.5%, disc displacement in 100% and disc herniation in 75%. All degenerative lesions were predominantly found at L4/L5. Highly significant (p <0.001) association of radiculopathy with Modic changes, disc herniation, nerve root compression and spinal canal stenosis was found.
Conclusion: Signs of degenerative disc disease are significantly associated with radicular low back pain.
JAFMC Bangladesh. Vol 17, No 2 (December) 2021: 47-51
Health Perspective of Local and United Nation Personnel Reported in Bangladesh Level-II Hospital in Liberia
Authors: Haque AQM Shamsul
Published: May 2022

Introduction: Liberia is one of civil war-ravaged country, where peace process started by United Nation (UN) in 2003. Bangladesh is also included in peacekeeper’s mission including medical services and sent a Level-II Hospital named Banmed 10 which started works in Liberia in June 2013 and provide medical support to UN personnel as well as local people and civil military cooperation (CIMIC). Pictures of health problems of these personnel are drawn in this study.
Objectives: To find out the disease pattern of natives and multinational UN personnel as well as local people visiting Level- II Hospital, Banmed-10.
Materials and Methods: It was a descriptive type of observational study conducted among 6906 patients from 18 Jun 2013 to 31 March 2014. Data were collected from the outdoor/indoor medical records and documents. Relevant data are sorted out and entered in computer for necessary calculation. Results are arranged in appropriate tables showing percent or proportion.
Results: Common diseases are found in UN personnel and Liberians such as Fever (Nos), Malaria, RTI, Diarrhoea, Backache, Arthritics, Hernia and others. Fever (Nos) most common 83.7% among the locals and 65.3% among the UN personnel. Malaria 16.3% among the locals and 11.3% among the UN personnel. Some special cases were also found like Lassa and Ebola.
Conclusion: Bangladesh level-II Hospital has been providing medical support to UNMIL personnel as well as to local people as they are highly dependent on it due to heavy destruction of their medical facilities during civil war. Bangladesh earns commendable reputation by their high professionalism, quality service and dedication to the responsibility.
JAFMC Bangladesh. Vol 17, No 2 (December) 2021: 52-56
Sickness Profile of the Children Attending Paediatric Out Patient Department at Combined Military Hospital, Dhaka
Authors: Rahim Md A
Published: May 2022

Introduction: Children are the major victims of mortality and morbidity in our society. Though Bangladesh has achieved significant success in reducing mortality of children over the past few decades, but still it is alarming.
Objective: To determine the sickness profile of the children under 12 years attending paediatric outpatient department at combined Military Hospital (CMH), Dhaka.
Methods: This descriptive cross-sectional study was conducted from July to December 2012 to determine the sickness profile of the children under 12 years attending paediatric outpatient department at CMH, Dhaka. A total of 143 children were selected for this study and data were collected with a semistructured questionnaire and check list by face-to-face interview of the parents and reviewing medical records of the children.
Results: Among the subjects, 60.1% were male and 39.9% were female with mean age 4.8(±3.6) years. Regarding mother’s education, 62.2% were SSC or equivalent qualified, 23.1% HSC, 0.7% Diploma and 4.9% were Graduated or above. Average family size of the children was 4 (±0.7). Most of the mothers (97.2%) were housewives. The diseases suffered by children included respiratory diseases (43.4%), gastro intestinal diseases (17.5%), pyrexia (16.8%), neurological diseases (14.0%) and non-communicable diseases (8.4%). Respiratory diseases (43.4%) were more common in children of housewives’ mother (43.9%) while neurological diseases (14.0%) were prevalent in children of serving mother and these differences were statistically significant (P=0.027). Regarding age and diseases, respiratory diseases were more in <1 year children while pyrexia and neurological diseases were more in 6-9 years children. About mother’s education and diseases; diseases of GIT, pyrexia, respiratory and neurological were prevalent in mothers of SSC or equivalent level. The association of mothers’ education level and diseases of children suffering from were statistically significant (P<0.05).
Conclusion: To improve the situation, health care providers and the parents should be aware enough of prevailing major diseases of the children and there by necessary measures along with health education especially for mother should be taken accordingly.
JAFMC Bangladesh. Vol 17, No 2 (December) 2021: 76-80
Prevalence of Metabolic Syndrome in Patients with Psoriasis
Authors: Alam Bhuiyan Muhammed Ashraful , Jamal Jweena Binte , Latif Khan Md Abdul , Khan Md Shirajul Islam , Khaled Huda Kazi Mohammad
Published: May 2022

Introduction: Psoriasis is a multifactorial inflammatory disease of chronicity characterized by well-defined erythematous plaques covered with silvery white scales present particularly over extensor surfaces of extrimities, trunk and scalp associated with a higher cardiovascular risk. Metabolic syndrome is one of the significant predictor of cardiovascular events.
Objective: To determine the prevalence of metabolic syndrome in patients with psoriasis.
Materials and Methods: This cross-sectional study was conducted in Department of Dermatology & Venereology, Combined Military Hospital (CMH), Dhaka from 01 May 2014 to 30 October 2014. One hundred four confirmed psoriasis patients were selected for this study. Complete history, thorough clinical examination including height, weight, Blood pressure (BP), waist circumference (WC) and relevant investigations were done in all patients.
Results: Out of 104 patients of psoriasis, 32(30.8%) patients had metabolic syndrome and 72(69.2%) patients were without metabolic syndrome. In group I (with metabolic syndrome) majority 16(50.0%) patients belonged to age 51-60 years and in group II (without metabolic syndrome) 25(34.7%) patients belonged to age 21-30 years and the difference was significant statistically (p<0.05) between two groups. Among the comorbidities, DM and HTN were found 26(81.3%) & 24(75%) in group I and 4(16.7%) & 18(25%) in group II respectively which was significant statistically (p<0.05) between two groups.
Conclusion: Psoriatic patients have a higher prevalence of metabolic syndrome, which can favour cardiovascular events. The dermatologists should be very keen to find out the elements of metabolic syndrome and suggests appropriate measures to reduce cardiovascular morbidity in addition to optimal dermatologic treatment of psoriasis.
JAFMC Bangladesh. Vol 17, No 2 (December) 2021: 81-85
El marketing digital en las microempresas familiares de Guayaquil en la postpandemia
Authors: Viteri-Rade Layla , Maldonado-de la Cruz Walter , Bernal-Luna Claudia
Published: May 2022

En Ecuador, las microempresas son fundamentales para el desarrollo de su sociedad, debido a que muchas de las organizaciones mantienen este esquema. Las familias buscan generar el emprendimiento apostando a sus habilidades para generar el crecimiento económico dentro de la misma. Por tanto, el objetivo de esta investigación es analizar el marketing digital en las microempresas familiares de Guayaquil en la postpandemia. La metodología aplicada en el desarrollo de la investigación es de carácter cuantitativo con un diseño no experimental, con tipo de investigación de campo y niveles descriptivo y explicativo. La muestra fue de 382 microempresas familiares las cuales están comprendidas en los sectores económicos más importantes como son el comercio, manufactura, servicios y agricultura, ganadería, silvi-cultura y pesca. Se tiene que las microempresas familiares de Guayaquil no conocen la importancia del marketing digital como mecanismos para incrementar y desarrollar la sustentabilidad de estas organizaciones. Este desconocimiento incide directamente en la implementación de la misma, pero al conocer su importancia desean aplicar sus estrategias para poder captar más clientes o usuarios y así incrementar el rendimiento económico. Como conclusión se deben adoptar nuevas tendencias para la supervivencia de las microempresas en este mercado exigente, donde el comercio electrónico ha ganado terreno permitiendo poder mostrar sus productos, innovar, y aumentar sus ingresos económicos, lo que conlleva a un crecimiento y fortalecimiento de sus ventas.
Okul öncesi öğretmenlerinin biyolojik çeşitlilik kavramına ilişkin görüşlerinin incelenmesi
Authors: KOCA Ceren , AYDIN Eren , SERT Hakan
Published: May 2022

Biyolojik çeşitlilik eğitiminin 'doğa ile ilgili olduğu' ve bu nedenle yeni bir şey olmadığı iddia edilebilir çünkü eğitimciler uzun yıllardır insanlar çeşitli bitki ve hayvanları ve bunların yaşam alanlarını anlamaları ve deneyimlemeleri için fırsatlar yaratmaktadırlar. Bu nedenle biyolojik çeşitlilik eğitimine artık daha çok süreç odaklı, katılımcı ve eyleme yönelik bir öğrenme yaklaşımı anlamına gelen sürdürülebilir kalkınma için eğitim yöntemleriyle yaklaşılmaktadır. Okul öncesi eğitim ile ilgili biyolojik çeşitlilik kavramına ve eğitimine ilişkin yapılan çalışmaların yakın zamana kadar nadir olduğu, ancak son on yılda bu alanda dikkate değer bir artış görülmüştür. Ancak, okul öncesi öğretmenlerine yönelik yapılan çalışmalarda açık bir araştırma eksikliği vardır. Yapılan bu çalışmanın amacı; okul öncesi öğretmenlerinin biyolojik çeşitlilik kavramına ilişkin görüşlerinin incelenmesidir. Bu doğrultuda; okul öncesi öğretmenlerinin biyolojik çeşitlilik kavramına ilişkin görüşleri, okul öncesi öğretmenlerinin Türkiye’nin biyolojik çeşitliliği hakkında düşünceleri, okul öncesi öğretmenlerinin çocukların ve kendilerinin biyolojik çeşitlilik algılarının geliştirilmesi ile ilgili görüşleri ve okul öncesi öğretmenlerinin ve okul öncesi dönem çocuklarının biyolojik çeşitlilik algılarının geliştirilmesinin çevre farkındalıklarına etkileri hakkındaki görüşleri incelenmiştir. Bu çalışma nitel araştırma yöntemlerinden olgubilim (fenomenoloji) deseni ile yürütülmüştür. Bu araştırmada uygun örnekleme yöntemi kullanılmıştır. Katılımcılar Türkiye’de devlet anaokullarında görev yapan on sekiz (18) okul öncesi öğretmenden oluşmaktadır. Araştırmada nitel veri toplama yöntemi ve bu yönteme uygun olarak yarı yapılandırılmış görüşme formları kullanılmıştır. Okul öncesi öğretmenlerinin biyolojik çeşitliliğin tanımına ilişkin görüşlerine bakıldığında biyolojik çeşitliliği tür çeşitliliği, yaşamın birlikteliği, ekosistem olarak tanımladıkları görülmüştür. Ayrıca, öğretmenler yeterli bilgi sahibi olmamaları sebebiyle, sınıflarında biyolojik çeşitlilik eğitimine yeterli ilgiyi gösteremediklerini belirtmişlerdir.
Gelişen zihniyetin PISA 2018 başarısını yordama gücü ve düzenleyici değişken olarak sosyoekonomik düzeyin rolü
Authors: KAYA Sibel , BİLİCAN DEMİR Safiye
Published: May 2022

Dweck ve arkadaşları tarafından geliştirilen zihniyet (mindset) teorisi ve onun eğitim alanındaki yansımaları uluslararası alanyazında oldukça dikkat çekmiştir. Ancak Türkiye’de bu konuda yapılan çalışmaların sayısı çok sınırlıdır. Bu teoriye göre, bazı insanlar, zekânın çalışma ve eğitim yoluyla değişip gelişebileceğine inanırken, bazıları ise bu özelliklerin kalıtsal ve sabit olduğunu düşünmektedir. Zekânın gelişebileceğine inanmak gelişen zihniyet (growth mindset) olarak adlandırılırken; zekânın kalıtsal ve değişmez olduğuna inanmak sabit zihniyet (fixed mindset) olarak adlandırılır. Zihniyet teorisini konu alan çalışmalarda, gelişen zihniyete sahip olmanın akademik başarıyı olumlu yönde etkilediği gözlenirken, sabit zihniyetin genelde başarıyı düşürdüğü gözlenmiştir. Bu araştırmada gelişen zihniyetin (growth mindset) öğrencilerin PISA fen ve matematik başarıları üzerinde etkisinin olup olmadığı ve bu etkinin sosyoekonomik düzeye göre farklılık gösterip göstermediği incelenmiştir. Uluslararası Öğrenci Değerlendirme Programı (PISA) 2018 Türkiye veri setiyle, çok düzeyli regresyon analizi yapılmıştır. Analizler sonucunda hem gelişen zihniyetin hem de sosyoekonomik düzeyin öğrenci başarısını anlamlı biçimde yordadığı ancak gelişen zihniyetin etkisinin sosyoekonomik düzeye göre farklılaşmadığı sonucuna ulaşılmıştır. Yani, gelişen zihniyet farklı sosyoekonomik düzeydeki öğrencilerin fen ve matematik başarısının benzer şekilde anlamlı bir yordayıcısı olmuştur. Öğrenci ve öğretmenlerin gelişen zihniyet konusunda bilgilendirilmeleri ve sınıf içi uygulamaların gelişen zihniyeti destekleyici yönde düzenlenmesi tavsiye edilmektedir. Öğrencilere gelişen zihniyetin aşılanması özellikle Bilim-Teknoloji-Mühendislik-Sanat-Matematik (STEAM) alanlarına yönelmeleri açısından da önem teşkil etmektedir.
KEBIJAKAN PROGRAM POJOK ASI UNTUK TERCAPAINYA ASI EXCLUSIVE PEGAWAI RUMAH SAKIT UMUM DAERAH (RSUD) I LAGALIGO KABUPATEN LUWU TIMUR
Authors: Susilowati Endang , Chairunisa Frida , Ahmad Muh. Syarif
Published: May 2022

Masalah pokok dalam penelitian ini adalah kebijakan program pojok ASI bagi Pegawai di RSUD I Lagaligo Kabupaten Luwu Timur untuk tercapainya ASI Esklusif. Tujuan penelitiaan ini yaitu untuk mengetahui dan menganalisis kebijakan pojok ASI bagi pegawai di RSUD I Lagaligo, melalui faktor predisposisi, pemungkin dan faktor penguat. Penelitian ini dilakukan dengan pendekatan kualitatif dan metode deskriptif. Adapun teknik pengumpulan data yang  digunakan melalui wawancara, observasi, dan telaah dokumen kemudian dianalisis mendalam untuk menjawab permasalahan yang terkait dengan kebijakan program pojok ASI bagi pegawai di RSUD I Lagaligo. Hasil penelitian menunjukkan bahwa kebijakan program pojok ASI bagi pegawai di RSUD I Lagaligo: (1) Predisposisi atas pojok ASI pada RSUD I Lagaligo para pengambil kebijakan sangat memahami akan pentingnya keberadaan ruang pojok ASI, dimana sistem regulasi mensyaratkan agar RSUD I lagaligo sebagai penyelenggara layanan publik menyiapkan pojok ASI sehingga setiap pekerja perempuan yang menyusui dapat menaikkan persentase pemberian ASI, terjaganya nilai Privasi serta mendukung kesehatan ibu dan bayi. (2) Pemungkin atas RSUD I Lagaligo telah memiliki petugas yang terlatih untuk mengedukasi pekerja perempuan yang menyusui dan tersedianya alternatif ruangan atau sarana dan prasana sebagai penunjang tercapainya ASI Ekslusif (3) dengan keberadaan pojok ASI, pekerja perempuan yang menyusui telah mendapatkan dukungan keluarga, rekan kerja serta tersedianya petugas yang terlatih memberikan edukasi.
Demystification of Chester porphyria: A nonsense mutation in the porphobilinogen deaminase gene
Authors: Poblete-Gutiérrez P , Wiederholt T , Martinez-Mir A , Merk HF , Connor JM , Christiano AM , Frank J
Published: May 2022

The porphyrias arise from predominantly inherited catalytic deficiencies of specific enzymes in heme biosynthesis. All genes encoding these enzymes have been cloned and several mutations underlying the different types of porphyrias have been reported. Traditionally, the diagnosis of porphyria is made on the basis of clinical symptoms, characteristic biochemical findings, and specific enzyme assays. In some cases however, these diagnostic tools reveal overlapping findings, indicating the existence of dual porphyrias with two enzymes of heme biosynthesis being deficient simultaneously. Recently, it was reported that the so-called Chester porphyria shows features of both variegate porphyria and acute intermittent porphyria. Linkage analysis revealed a novel chromosomal locus on chromosome 11 for the underlying genetic defect in this disease, suggesting that a gene that does not encode one of the enzymes of heme biosynthesis might be involved in the pathogenesis of the porphyrias. After excluding candidate genes within the linkage interval, we identified a nonsense mutation in the porphobilinogen deaminase gene on chromosome 11q23.3, which harbors the mutations causing acute intermittent porphyria, as the underlying genetic defect in Chester porphyria. However, we could not detect a mutation in the coding or the promotor region of the protoporphyrinogen oxidase gene that is mutated in variegate porphyria. Our results indicate that Chester porphyria is neither a dual porphyria, nor a separate type of porphyria, but rather a variant of acute intermittent porphyria. Further, our findings largely exclude the possibility that a hitherto unknown gene is involved in the pathogenesis of the porphyrias.
De novo mutation found in the porphobilinogen deaminase gene in Slovak acute intermittent porphyria patient: Molecular biochemical study
Authors: Ulbrichova D , Flachsova E , Hrdinka M , Saligova J , Bazar J , Raman CS , Martasek P
Published: May 2022

The porphyrias are group of mostly inherited disorders in which a specific spectrum of accumulated and excreted porphyrins and heme precursors are associated with characteristic clinical features. There are eight enzymes involved in the heme synthesis and defects in seven of them cause porphyria. Four of them are described as acute hepatic porphyrias, which share possible precipitation of acute attacks with symptoms engaging the nervous system. Acute intermittent porphyria (AIP), caused by partial deficiency of the porphobilinogen deaminase (PBGD), is the most frequent among hepatic porphyrias. Clinical expression is highly variable and ~ 90 % of AIP heterozygotes remain asymptomatic throughout life. During systematic genetic analysis of the AIP patients diagnosed in the Czech and Slovak Republics, we found a special case of AIP. In a 15-year-old boy with abdominal and subsequent neurological symptomatology, we identified de novo mutation 966insA within the PBGD gene leading to a stop codon after 36 completely different amino acids compared to the wt-sequence. To establish the effects of this mutation on the protein structure, we expressed mutant constructs with described mutation in E. coli and analyzed their biochemical and enzymatic properties. Moreover, computer-assisted protein structure prediction was performed.
Biogenesis of eukaryotic cytochrome c oxidase
Authors: Stiburek L , Hansikova H , Tesarova M , Cerna L , Zeman J
Published: May 2022

Eukaryotic cytochrome c oxidase (CcO), the terminal component of the mitochondrial electron transport chain is a heterooligomeric complex that belongs to the superfamily of heme-copper containing terminal oxidases. The enzyme, composed of both mitochondrially and nuclear encoded subunits, is embedded in the inner mitochondrial membrane, where it catalyzes the transfer of electrons form reduced cytochrome c to dioxygen, coupling this reaction with vectorial proton pumping across the inner membrane. Due to the complexity of the enzyme, the biogenesis of CcO involves a multiplicity of steps, carried out by a number of highly specific gene products. These include mainly proteins that mediate the delivery and insertion of copper ions, synthesis and incorporation of heme moieties and membrane-insertion and topogenesis of constituent protein subunits. Isolated CcO deficiency represents one of the most frequently recognized causes of respiratory chain defects in humans, associated with severe, often fatal clinical phenotype. Here we review recent advancements in the understanding of this intricate process, with a focus on mammalian enzyme.
Effects of Self-Massage and Foot Exercises on Lumbar Spine Pain and Functional Condition in Sedentary Men
Authors: Gorodeckaitė Adrija , Šilinė Ligita
Published: May 2022

Background. Lumbar pain is one of the most common disorders of the musculoskeletal system in workers who sit for prolonged periods of time. Prolonged sitting hours change muscle activity and create tension, which negatively affects the structure of the fascia. Myofascial exercises for the posterior superficial chain have been shown to reduce lumbar pain, but the effect of self-massage and foot exercises on the functional condition of the lumbar in office workers is unclear.

The aim. To assess the effect of self-massage and foot exercises on lumbar pain and functional condition in male office workers.

Methods. The study included 20 men (25.8 ± 2,6 year) (10 in the experimental group, 10 in the control group) engaged in sedentary work and experiencing chronic non-specific lumbar pain. Before and after the study, a pain intensity assessment was performed using the numerical rating scale (NRS), a functional status assessment using the Oswestry questionnaire, and an assessment of the superficial length of the back superficial chain (lower part) using the toe reach test. For the experimental group, 5 times a week for 10 weeks for 10 minutes, self-massage was applied to each foot; and 3 times a week for 30 minutes, exercises for the feet.

Results. After self-massage and foot exercises, the intensity of pain and functional disability decreased significantly (p <0.001), and the length of the back superficial chain (lower part) increased (p <0.001). Functional disability increased in the control group (p <0.001). After the study, functional disability differed significantly between groups (p = 0.02).

Conclusion. Self-massage and foot exercises improved functional condition and reduced lumbar pain in male office workers.

Keywords: low back pain, fascia, myofascial chain, massage, physiotherapy.
Effect of Kinesiotaping and Sham Taping on Knee Function in Knee Osteoarthritis. A Randomized Clinical Trial
Authors: Žlibinaitė Laura , Bruner Ivan , Katkutė Gintarė , Dudonienė Vilma
Published: May 2022

Background. The prevalence of knee osteoarthritis has increased significantly and continued to increase in recent decades. Different interventions are used for the treatment: therapeutic exercises, kinesiotaping and placebo. The application of these therapies remains controversial.

The aim. To determine the effect of kinesiotaping and sham taping on knee function and patient’s functional mobility in knee osteoarthritis.

Methods. A randomized clinical trial (ClinicalTrials.gov Identifier: NCT05320562) was performed in one of the Lithuanian clinics. Thirty patients with osteoarthritis of the knee (age 58.1 ± 3.9 years) were randomly assigned to three groups of ten patients. Patients in the control group received therapeutic exercises; the sham taping group received therapeutic exercise and sham taping; and the kinesiotaping group received therapeutic exercises and kinesiotaping.

Results. Subjects’ knee pain decreased by an average of two points after the interventions (p <0.05) in all three groups. Results of “Up and go” test improved significantly in the sham taping and kinesiotaping groups. The results of the 10-meter walking test improved significantly in the kinesiotaping group. Thigh muscle strength improved after the interventions (p <0.05) in all three groups. Knee range of motion significantly improved only in the kinesiotaping group.

Conclusions. All three interventions significantly reduced subjects’ knee pain and increased thigh muscle strength, but kinesiotaping significantly improved subjects’ functional mobility.

Keywords: knee osteoarthritis, kinesiotaping, therapeutic exercises, sham taping, pain.
Short and Long-term Effects of Mobilization with Movement and Eccentric Overload to Hand Pain and Function in the Treatment of Lateral Epicondylitis
Authors: Svalbonas Lukas , Masiulis Nerijus , Jurgelaitienė Giedrė , Janušonienė Laura
Published: May 2022

Aim. To determine and compare short and long-term effects of mobilization with movement and eccentric overload to hand pain and function in the treatment of lateral epicondylitis.

Problem of research & hypothesis. The eccentric overload exercises are one of the best methods in tendinopathy treatment. Mobilization with movement is largely used as an effective treatment method for lateral epicondylitis. Only the short-term effects of these methods in lateral epicondylitis are often evaluated, but no studies were found to use these methods in combination and to evaluate their long-term effects.

Methods. The study included individuals (n=30) aged 30–54 years who had been diagnosed with lateral epicondylitis. Subjects were tested by assessing their perceived pain using the visual analogue scale (VAS); handgrip strength was assessed by a dynamometer. The QuickDASH questionnaire was used to assess hand function and perceived disability.

Subjects were randomly divided into three groups: mobilization with movement group (n=10), eccentric overload group (n=10), and combined group (combined mobilization with movement and eccentric overload exercises) (n=10). All subjects got 10 physiotherapy procedures, short-term effect evaluated after 10 procedures of physiotherapy, long-term effect evaluated after 2, 6 and 12 weeks post treatment course.

Results. Study results revealed that all treatment methods had a significant (p<0.05) effect on pain reduction, increase in handgrip strength as well as improvement in hand function and disability.

In follow-up assessments at 2, 6 and 12 weeks after the treatment, the most altered indicators of pain intensity, pain-free handgrip strength and hand function were seen in the mobilization with movement group.

Conclusions. An application of mobilization with movement in the treatment of lateral epicondylitis had the greatest positive effect on pain intensity, maximum handgrip strength and hand function and disability compared to mobilization with movement combined with eccentric overload and eccentric overload exercises alone.

Keywords: lateral epicondylitis, mobilization with movement, eccentric overload, pain intensity, hand pain-free grip strength.
CHINA’S SOFT POWER: CULTURE AND SPORTS
Authors:   St. Petersburg State University, St. Petersburg, Russian Federation, XIAO LIU , ZHAOYI LIU
Published: May 2022

The authors of this study aim to highlight the features of soft power specifically for China’s modern politics. As examples, the cultural policy and its specifics, characteristic of China, as well as successes in the sports field, in particular the implementation of major sports competitions, are analyzed. Of course, these are only components of the soft power policy pursued by the state in recent years, but it is these differences that allow China to achieve a number of advantages in the modern world and improve the country’s image in the world. These features make up the uniqueness of China and are based on a unique interweaving of history, philosophy, economics, sustainable development and, of course, culture and sports. The conclusions reached by the authors indicate that China uniquely combines the humanistic philosophy of antiquity and modern economics and technology, Thus, Confucianism is perfectly combined with modern technologies and economic development and high-level sports games, the organization of which also reflects ambitions and modern achievements.
PERSPECTIVES AND CONTRADICTIONS OF VALUE COHESION WITHIN THE INFORMATION SUPPORT SYSTEM OF THE RUSSIAN ARMED FORCES
Authors:   Military University of the Ministry of Defense of the Russian Federation, Moscow, Russian Federation, GORBACHEV SERGEY
Published: May 2022

Aim of the study. The study aims to establish the relevance of value cohesion within the information support system of the Russian Armed Forces using the ontology of values. The paper describes axiological contradictions in contemporary Russian society, as well as their origins and types. The study reveals that Russia historically focused on searching for and promoting intrinsic, objectively real values. Moreover, it describes the challenges and threats posed by axiological simulations and imitations. Conclusions. The author concluded that the Russian Armed Forces experience a series of value clashes, stemming from external political influence, the contradictions between the values of elites and of the common people, as well as the lack of terminology consistency within the Armed Forces themselves. These clashes threaten the success of information support within the Russian Armed Forces, putting their duty to protect the state and its people in jeopardy.
DEVELOPMENT OF RELATIONS BETWEEN THE KYRGYZ REPUBLIC AND THE PEOPLE’S REPUBLIC OF CHINA WITHIN THE FRAMEWORK OF THE SHANGHAI COOPERATION ORGANIZATION OF THE CONTEXT OF “ONE BELT, ONE ROAD” INITIATIVE
Authors:   Bishkek State University named after K. Karasaev, Bishkek, Kyrgyz Republic, ALAFATE ABULAITI
Published: May 2022

The article is devoted to the problems of developing relations between the Kyrgyz Republic and the PRC within the framework of the SCO in the period from 2013 to 2020. China’s launch of its economic initiative “One Belt, One Road” (OBOR) in the autumn of 2013 became a major factor in the further transformation of China’s relations with the countries of Central Asia. These processes naturally affected the most important international regional organization in the region - the Shanghai Cooperation Organization, since it was in its format that a significant part of the cooperation between the Kyrgyz Republic and the PRC proceeded. But with the beginning of the implementation of the BRI by Beijing, a new model of relations between the PRC and the Kyrgyz Republic begins to take shape, in which economic issues were preferred to be resolved bilaterally, and problems related to security issues within the framework of the SCO. But since the Ufa summit of the SCO in 2015, this regional structure has been further developed, as a result of which much more attention is being paid to economic partnership within its framework, which caused a deepening of relations in this area, including between Kyrgyzstan and China.
ANALISIS PENGARUH KUALITAS PELAYANAN DAN KEBIJAKAN HARGA TERHADAP LOYALITAS KONSUMEN (Studi Kasus: PT. GDI
Authors: Hanggara Fuad Dwi , Elba Ridha Arrazy , Dermawan Aulia Agung
Published: May 2022

Loyalty is something that cannot be bought with money, but can be obtained if you try to increase trust in customers. This study aims to analyze the effect of service quality variables and price policy on consumer loyalty variables. This research was conducted by dividing the questionnaire as an instrument. Customers today are faced with a number of alternative ways when choosing a store that suits their tastes. But every company must also be able to compete by setting itself up for changes and developments that exist, both from outside and inside so that a company can maintain this competition. The method of analysis was carried out by means of quantitative descriptive methods through survey techniques using questionnaires. The population used is 100 respondents, and the number of samples taken is 96 respondents. Data analysis was carried out using multiple linear regression analysis. The data quality test in this study uses validity and reliability tests, the classical assumption test in this study uses the normality test, multicollinearity test, and heteroscedasticity test and the effect test uses multiple linear regression analysis and analysis of the coefficient of determination (R2), while hypothesis testing in this study uses t-test and F test using IBM SPSS Statistics version 25 program.
USULAN PERBAIKAN KUALITAS PADA TANGKI AIR MENGGUNAKAN METODE FMEA DAN FTA
Authors: Aziz Muhammad chabibi , Andesta Deny
Published: May 2022

Along with the world's competition in the manufacturing industry, companies are required to increase productivity and quality in the resulting production. Companies engaged in construction and fabrication that produce water filter tanks located in Gresik Regency, in completing requests from customers always prioritize quality first and the company will try to win the competition by focusing on customer satisfaction. So far, the production process is not optimal because the number of defects is still too many. Product defects in the form of welding defects that occur during the production process, then painting defects that occur during finishing and symmetry defects in the machining process. To improve the production process, it is necessary to identify the type of failure, the consequences of the failure, and the cause of the problem to provide suggestions for improvement. To improve the production process in the water tank using the FMEA and FTA methods. Based on the FMEA method, the selected production process to identify based on the highest RPN, namely the welding process, painting process, and machining process that causes symmetry. This is done to minimize product defects and provide suggestions for improvement. After obtaining the RPN value from the FMEA method, then conducting an analysis using the FTA method to find the root cause of the problem that resulted in the production process being not optimal
Daily Inhaled Corticosteroids Treatment Abolishes Airway Hyperresponsiveness to Mannitol in Defence and Police Recruits
Authors: Lake Clair D. , Wong Keith K. H. , Perry Clare P. , Koskela Heikki O. , Brannan John D.
Published: May 2022

Background

Airway hyperresponsiveness (AHR) is a key pathophysiological feature of asthma and causes exercise-induced bronchoconstriction (EIB). Indirect bronchial provocation tests (BPTs) (e.g., exercise, mannitol) aid to diagnose asthma and identify EIB. Daily inhaled corticosteroids (ICS) can abolish AHR caused by indirect stimuli. Where strenuous physical exertion is integral to an occupation, identification of those at risk of EIB is important and documentation of inhibition of AHR with ICS is required before recruitment.

Methods/Objectives

A retrospective analysis was performed on 155 potential recruits with AHR to mannitol who underwent follow-up assessment after daily ICS treatment to determine the proportion that can abolish AHR using ICS and to determine any predictors of the persistence of AHR.

Results

Airway hyperresponsiveness was abolished in the majority (84%, n = 130) over the treatment period (mean ± SD 143 ± 72days), and it was defined as the provoking dose of mannitol to cause a 15% fall in FEV1 (cumulative inhaled dose of mannitol to cause 15% fall in FEV1, PD15) improved from (GeoMean) 183 to 521 mg. Compared with recruits in whom AHR was abolished with daily ICS (i.e., no 15% fall in FEV1 to the maximum cumulative dose of mannitol of 635 mg), in those where AHR remained (16%, n = 25), baseline AHR was more severe (PD15: 85 mg vs. 213 mg, P < 0.001), baseline FEV1% was lower (89 vs. 96%; 95%CI:2–12, P=0.004), and they had a longer follow-up duration (180 vs. 136 days; 13–74, P = 0.006). Baseline FEV1% (adjusted odds ratio 0.85; 95%CI:0.77–0.93), FEV1/FVC (0.78; 0.67–0.90), FEF25−75% (1.15; 1.06–1.25), and airway reactivity to mannitol (%Fall/cumulative dose of mannitol multiplied by 100) (1.07; 1.03–1.11) predicted AHR remaining after daily ICS.

Conclusion

Airway hyperresponsiveness to mannitol can be abolished after 20 weeks of daily treatment with ICS. Inhibition of AHR is likely due to attenuation of airway inflammation in response to ICS treatment. Increased airway reactivity and lower spirometry variables predicted the persistence of AHR. Thus, those with a slower response to daily ICS on AHR can potentially be identified at the commencement of monitoring ICS using inhaled mannitol.
Impact of Food Matrices on Digestibility of Allergens and Poorly Allergenic Homologs
Authors: Akkerdaas J. H. , Cianferoni A. , Islamovic E. , Kough J. , Ladics G. S. , McClain S. , Poulsen L. K. , Silvanovich A. , Pereira Mouriès L. , van Ree R.
Published: May 2022

Background

Protease resistance is considered a risk factor for allergenicity of proteins, although the correlation is low. It is nonetheless a part of the weight-of-evidence approach, proposed by Codex, for assessing the allergenicity risk of novel food proteins. Susceptibility of proteins to pepsin is commonly tested with purified protein in solution.

Objective

Food proteins are rarely consumed in purified form. Our aim was to evaluate the impact of experimental and endogenous food matrices on protease susceptibility of homologous protein pairs with different degrees of allergenicity.

Methods

Porcine and shrimp tropomyosin (ST) were subjected to sequential exposure to amylase, pepsin, and pancreatin in their respective endogenous matrix (pork tenderloin/boiled shrimp) and in three different experimental matrices (dessert mousse [DM], soy milk [SM], and chocolate bar [CB]). Digestion was monitored by immunoblotting using tropomyosin-specific antibodies. Recombinant peach and strawberry lipid transfer protein were biotinylated, spiked into both peach and strawberry fruit pulp, and subjected to the same sequential digestion protocol. Digestion was monitored by immunoblotting using streptavidin for detection.

Results

Chocolate bar, and to a lesser extent SM, had a clear protective effect against pepsin digestion of porcine tropomyosin (PT) and to a lesser extent of ST. Increased resistance was associated with increased protein content. Spiking experiments with bovine serum albumin (BSA) confirmed the protective effect of a protein-rich matrix. The two tropomyosins were both highly resistant to pepsin in their protein-rich and lean native food matrix. Pancreatin digestion remained rapid and complete, independent of the matrix. The fat-rich environment did not transfer protection against pepsin digestion. Spiking of recombinant peach and strawberry lipid transfer proteins into peach and strawberry pulp did not reveal any differential protective effect that could explain differences in allergenicity of both fruits.

Conclusions

Protein-rich food matrices delay pepsin digestion by saturating the protease. This effect is most apparent for proteins that are highly pepsin susceptible in solution. The inclusion of food matrices does not help in understanding why some proteins are strong primary sensitizers while homologs are very poor allergens. Although for induction of symptoms in food allergic patients (elicitation), a protein-rich food matrix that may contribute to increased risk, our results indicate that the inclusion of food matrices in the weight-of-evidence approach for estimating the potential risks of novel proteins to become allergens (sensitization), is most likely of very limited value.
Predicting Topographic Effect Multipliers in Complex Terrain With Shallow Neural Networks
Authors: Santiago-Hernández J. X. , Román Santiago A. , Catarelli R. A. , Phillips B. M. , Aponte-Bermúdez L. D. , Masters F. J.
Published: May 2022

This study applies computationally efficient shallow neural networks to predict topographic effect multipliers directly from digital elevation data obtained from complex terrain, such as mountainous areas. Data were obtained from boundary layer wind tunnel (BLWT) modeling of surface wind flow over six regions in mainland Puerto Rico and its municipal islands. The results demonstrate an improvement over linear regression models, even for computationally efficient low neuron count and single hidden layer models. The paper proposes the development of a global BLWT data atlas to inform development of methods to predict topographic wind speedup for a diverse range of topography and surface roughness conditions. It also identifies knowledge gaps that could prevent standardization of data collected from different BLWT experimental designs.
Thermal Performance Study of a Cement-Based Mortar Incorporating EPS Beads
Authors: Horma Othmane , Charai Mouatassim , El Hassani Sara , El Hammouti Aboubakr , Moussaoui Mohammed A. , Mezrhab Ahmed
Published: May 2022

Recycling plastic waste has been one of the most significant challenges in the recent decade. The reuse of one of the most produced cellular plastics (i.e. EPS) within a conventional construction binder can contribute, simultaneously, to waste elimination and improving energy performances of the building envelopes. This work investigates the recycling of expanded polystyrene (EPS) waste within a cement-based matrix. The aim is to develop a lightweight, energy-efficient composite for eco-construction. Portland cement was mixed with a small amount of gypsum (4 wt%) before adding EPS aggregates ranging from 0–0.6 wt%. The thermal properties were determined using two different non-destructive methods, the transient plane source technique (Hot Disk Method) and the Flash method. The experimental results showed a remarkable decrease of 54, 12, and 36% in thermal conductivity, thermal diffusivity, and density, respectively. These results indicate the improvement of thermal resistance of EPS-cement-gypsum- mixes. In addition, water absorption and compressive tests revealed that cement-based composites containing EPS beads have improved durability and can be used for structural and insulation purposes. Finally, Numerical results indicated that energy savings of up to 18% may be achieved by applying produced waste-based mortar, underscoring the promise of using this product for building energy efficiency benefits.