bluuebunny/crossref_metadata_2025 huggingface dataset:
Στις ομάδες 12-βημάτων, η προσφορά βοήθειας βοηθάει αυτόν που την προσφέρει
Authors: Zemore Sarah E. , Kashutas Lee Ann , Ammon Lyndsay N.
Published: November 2022

Στόχοι: Η αρχή της θεωρίας της αμοιβαίας βοήθειας υποστηρίζει ότι στις ομάδες αυτοί που βοηθούν άλλους βοηθούν τον εαυτό τους. Η παρούσα μελέτη εξετάζει εάν τα άτομα που κάνουν θεραπεία για προβλήματα χρήσης αλκοόλ ή ναρκωτικών ωφελούνται προσφέροντας βοήθεια σε άλλους και με ποιον τρόπο αυτή η προσφορά βοήθειας σχετίζεται με την εμπλοκή τους στα 12-βήματα. Σχεδιασμός: Μακροχρόνια θεραπευτικά αποτελέσματα. Συμμετέχοντες: Ένα δείγμα 279 εξαρτημένων ατόμων από αλκοόλ ή/ και ναρκωτικά (162 άνδρες, 117 γυναίκες) σε μια κοινότητα με διαφορετικές εθνότητες, συγκεντρώθηκε μέσω του τύπου ή μέσω παραπομπών από θεραπευτικές δομές από την περιοχή της Northern California Bay. Οι συμμετέχοντες εντάχθηκαν σε ένα από τα προγράμματα των τεσσάρων ημερών. Μετρήσεις: Ένα ερωτηματολόγιο ελέγχου της παροχής βοήθειας μέτρησε το χρόνο που ανάλωσαν οι συμμετέχοντες στη διάρκεια της θεραπείας, προσφέροντας βοήθεια σε άλλους με το μοίρασμα εμπειριών, εξηγώντας πώς να λάβουν βοήθεια και προσφέροντας συμβουλές για την εξεύρεση κατοικίας ή εργασίας. Οι μετρήσεις για την εμπλοκή στα 12-βήματα και για τα αποτελέσματα της χρήσης ουσιών διεξήχθησαν στην αρχή και στην έρευνα follow-up έπειτα από 6 μήνες. Ευρήματα: Η προσφορά βοήθειας και η εμπλοκή στα 12-βήματα αναδύθηκαν ως σημαντικοί και συσχετιζόμενοι παράγοντες πρόβλεψης των αποτελεσμάτων της θεραπείας. Στο γενικό δείγμα, η αποχή στο follow-up ήταν δυνατόν να προβλεφθεί με σαφήνεια από την εμπλοκή στα 12 βήματα στο follow-up αλλά όχι από την παροχή βοήθειας στη διάρκεια της θεραπείας. Παρ’ όλα αυτά, η προσφορά βοήθειας κατά τη διάρκεια της θεραπείας στα άτομα που συνέχιζαν να πίνουν κατά τη διάρκεια του follow-up, προέβλεπε μικρότερη πιθανότητα υπερβολικής κατανάλωσης αλκοόλ, ενώ οι επιδράσεις για την εμπλοκή στα 12-βήματα ήταν σαφείς. Συμπεράσματα: Τα ευρήματα υποστηρίζουν την αρχή της θεωρίας της αμοιβαίας βοήθειας και αποσαφηνίζουν τη διαδικασία των ομάδων των 12-βημάτων. Λέξεις-κλειδιά: Ομάδες 12- βημάτων, Ανώνυμοι Αλκοολικοί, προσφορά βοήθειας, θεραπευτικό αποτέλεσμα.
Κοιτάζοντας προς την πύλη εισόδου: Οι προσδοκίες ως πιθανός δρόμος μετάβασης απο το αλκοόλ στην κάνναβη
Authors: Wilner Paul
Published: November 2022

Στόχος: Ο στόχος αυτής της μελέτης είναι να εξετάσει την υπόθεση εάν οι προσδοκίες για τα αποτελέσματα από τη χρήση κάνναβης είναι θετικότερες σε εφήβους που καταναλώνουν αλκοόλ από ό,τι σε αυτούς που δεν καταναλώνουν αλκοόλ. Συμμετέχοντες, χώρος: Οι συμμετέχοντες στη μελέτη ήταν 4.544 άτομα, 11-16 χρονών, από οκτώ γυμνάσια στο κεντρικό βοριο-δυτικό τμήμα της Αγγλίας. Διαδικασία: Οι συμμετέχοντες συμπλήρωσαν μόνοι τους ένα ανώνυμο ερωτηματολόγιο το οποίο περιελάμβανε ενότητες σχεδιασμένες να εντοπίσουν τις προσδοκίες των εφήβων σχετικά με τα θετικά και τα αρνητικά αποτελέσματα από τη χρήση αλκοόλ και κάνναβης καθώς επίσης και ερωτήσεις σχετικές με την κατάχρηση ουσιών και άλλα συναφή θέματα. Αποτελέσματα: Προέκυψαν τέσσερις αξιόπιστες κλίμακες έξι ερωτήσεων οι οποίες χρησιμοποιήθηκαν, για να εκτιμήσουν το βαθμό προσδοκίας θετικών και αρνητικών αποτελεσμάτων από τη χρήση κάνναβης και αλκοόλ. Οι αρνητικές προσδοκίες ήταν αρκετά σταθερές σε όλες τις ηλικίες και τις συχνότητες χρήσης, ιδιαίτερα όσον αφορά το αλκοόλ. Παρόλα αυτά οι θετικές προσδοκίες και από τις δύο ουσίες αυξάνονταν ιδιαίτερα με την ηλικία και ανεξάρτητα από τη συχνότητα χρήσης. Οι θετικές προσδοκίες από το αλκοόλ και την κάνναβη σχετίζονταν με προσδοκίες για μελλοντική χρήση ουσιών και με μετρήσεις προβληματικής χρήσης όπως και με την αντίσταση στην επιρροή από τους ομοτίμους, υποστηρίζοντας την εγκυρότητα αυτών των μετρήσεων προσδοκίας και την πιθανή τους αξία ως διαγνωστικού εργαλείου. Η κύρια υπόθεση αυτής της μελέτης υποστηρίχθηκε. Για όσους ανέφεραν πως δεν έχουν χρησιμοποιήσει ποτέ κάνναβη, οι θετικές προσδοκίες για τα αποτελέσματα από τη χρήση κάνναβης αυξάνονταν, ενώ μειώνονταν οι αρνητικές προσδοκίες με την αυξανόμενη συχνότητα της χρήσης αλκοόλ. Συμπεράσματα: Τα αποτελέσματα ταιριάζουν με μια εκδοχή της «υπόθεσης πύλη εισόδου» για τη σχέση μεταξύ χρήσης αλκοόλ και κάνναβης (η χρήση αλκοόλ οδηγεί σε αλλαγές στις προσδοκίες από την κάνναβη συνεπώς και στη χρήση κάνναβης), αλλά ο σωστός έλεγχος για αυτήν την υπόθεση απαιτεί μακροχρόνιες έρευνες.
Αλκοολισμός και συννοσηρότητα: διάγνωση και αντιμετώπιση στο πλαίσιο του προγράμματος «ΑΘΗΝΑ»
Authors: Λιάππας Ι. , Παπαρρηγόπουλος Θ. , Τζαβέλλας Η. , Κοντοάγγελος Κ. , Καρύδης Χ. , Ραμπαβίλας Α.
Published: November 2022

Η παρούσα μελέτη αναφέρεται στον αλκοολισμό και τις συνδεόμενες με αυτόν διαταραχές που συνιστούν μείζον βιο-ψυχο-κοινωνικό πρόβλημα και συχνότατα μία δυσεπίλυτη θεραπευτική πρόκληση. Επικεντρώνεται κυρίως στα διαφοροδιαγνωστικά και θεραπευτικά ζητήματα που ανακύπτουν από τη συννοσηρότητα αλκοολισμού και διαφόρων ψυχοπαθολογικών καταστάσεων, όπως οι αγχώδεις και συναισθηματικές διαταραχές. Η υψηλή συχνότητα συνύπαρξης των καταστάσεων αυτών τεκμηριώνεται από τη διεθνή βιβλιογραφία και επιβεβαιώνεται από τα προσωπικά μας κλινικά δεδομένα. Ιδιαίτερης σημασίας είναι η ορθή διάκριση μεταξύ της πρωτοπαθούς και της δευτεροπαθούς ψυχιατρικής διαταραχής που επάγεται από την ψυχοτρόπο δράση του οινοπνεύματος και υποχωρεί έπειτα από την απόσυρσή του. Στην Πανεπιστημιακή Ψυχιατρική Κλινική του Αιγινητείου Νοσοκομείου λειτουργεί το πρόγραμμα «ΑΘΗΝΑ», που αποτελεί μία ανοικτή μονάδα απεξάρτησης από εθιστικές ουσίες και από το οινόπνευμα. Ειδικά για την αποτοξίνωση από το αλκοόλ, προβλέπεται περίοδος «κλειστής» εκούσιας νοσηλείας στο νοσοκομείο, μέσης διάρκειας ενάμιση μηνός, κατά την οποία γίνεται η απόσυρση από το οινόπνευμα με τη βοήθεια κατάλληλης φαρμακευτικής υποστήριξης, αντιμετωπίζονται τυχόν παθολογικά και ψυχοπαθολογικά προβλήματα, και τελικά γίνεται η διασύνδεση με την ανοικτή δομή του προγράμματος. Οι βασικές ψυχοθεραπευτικές τεχνικές που εφαρμόζονται είναι η ατομικού τύπου γνωσιακή/ συμπεριφοριστική θεραπεία και η οικογενειακή αντιμετώπιση συστημικού τύπου. Σύμφωνα με τα κλινικά/ ερευνητικά στοιχεία από την πενταετή λειτουργία του προγράμματος, προκύπτει ότι στις περιπτώσεις πρωτοπαθούς αλκοολισμού παρατηρείται σημαντική ύφεση της παράλληλης ψυχοπαθολογίας (καταθλιπτικής, αγχώδους, κοινωνικο-φοβικής) κατά τη φάση απόσυρσης από το αλκοόλ. Συνεπώς, το δεδομένο αυτό πρέπει να λαμβάνεται σοβαρά υπόψη στη διαγνωστική και θεραπευτική προβληματική του αλκοολισμού. Λέξεις ευρετηρίου: Αλκοολισμός – Κατάχρηση – Εξάρτηση – Αλκοόλ – Συννοσηρότητα – Κατάθλιψη – Άγχος – Κοινωνική φοβία – Θεραπεία – Πρόγραμμα «ΑΘΗΝΑ»
MAKNA AL-AR? DALAM AL-QUR’AN (Kajian Semantik Juz 28)
Authors: Arifin Ali zainal , Aisyah Aas siti
Published: November 2022

Penelitian ini membahas tentang makna kata al-ar? dalam Al-Qur’an juz 28. Kata al-ar? terkait erat dengan kehidupan manusia yaitu dengan tempat tinggal manusia, dalam terjemah Al-Qur’an hanya memberikan gambaran awal dari makna al-ar?, sehingga membutuhkan penjelasan lebih mendalam agar bisa mengetahui maknanya secara komprehensif. Penelitian ini menggunakan teori semantik Al-Qur’an Toshihiko Izutsu agar bisa mengetahui maknanya secara komprehensif. Tahapan yang dilakukan dalam penelitian ini adalah dengan mencari makna dasar, makna relasional dengan menggunakan analisis sintagmatik dan paradigmatik, kemudian meneliti makna historis yang dilihat dari aspek sinkronik dan diakronik, dan yang terakhir adalah mencari weltanschauung atau makna konseptual dari kata al-ar?. Yang mana dari penelitian tersebut menunjukkan bahwa kata al-ar? dalam juz 28 dibagi menjadi dua makna yaitu, bermakna bumi secara umum (Ithl?qu al-ma’?n?) dan bumi yang tujuh (sab’i ara??n). Kedua makna tersebut mengantarkan pada pandangan dunia Al-Qur’an atau weltanschauung terhadap kata al-ar? yang bermakna bumi sebagai tempat tinggal manusia.
ISU SOSIO-HISTORIS DALAM TAFSIR AL-QUR’AN AL-KARIM
Authors: Amir Ahmad nabil
Published: November 2022

This paper discusses socio-historical issues in kitab Tafsir al-Qur’an al-Karim penned by al-Ustaz H. A. Halim Hasan, H. Zainal Arifin Abbas dan Abdur Rahim Haitami. Kitab Tafsir al-Qur’an al-Karim by these trio scholars was among the pre-eminent works of contemporary tafsir in Indonesia acclaimed for its balanced method of commentary using transmitted narrative (al-naql) and rational judgement (al-‘aql) in commentary. Some crucial issues of politics addressed were justice, democracy, shura (consultation) and freedom while social issues treated were hypocrisy, history of the Children of Israel, prophethood, natural disposition, intercession, mysticism and arrangement of nature. The method was descriptive and analytical in highlighting political and social views brought forth in the Tafsir. The finding shows that the political and social issues addressed in this work have been significantly established. The accomplishment has positive implication in the development and reform of tafsir in modern times that critically assist in the religious movement for social justice and political reform in Indonesia
Democracia em Xeque: Um Estudo Comparativo sobre Detecção de Code Smells
Authors: Nunes Henrique Gomes , Vegi Lucas Francisco da Matta , Cruz Victor Pezzi Gazzinelli , Figueiredo Eduardo
Published: November 2022

Existem muitas ferramentas e técnicas diferentes para detecção de code smells. Alguns estudos indicam que as formas de detecção de smells podem variar significativamente mesmo quando aplicadas em um mesmo contexto. Visando avaliar e compreender se alguma forma de detecção automática de code smells provê resultados mais próximos da realidade, nesse artigo é realizada uma investigação quantitativa envolvendo três ferramentas de detecção de code smells e um sistema de votação que combina o uso dessas ferramentas. Todas essas formas de detecção de code smells foram comparadas com um oráculo proposto por especialistas para classificar uma classe como God Class. Por meio do uso de estatística descritiva, os resultados indicaram que a ferramenta JDeodorant apresenta melhor revocação na detecção de God Class quando usada individualmente e que o sistema de votação não gera ganhos significativos.
Perceptions and Difficulties of Software Engineering Students in Code Smells Refactoring
Authors: Bezerra Carla , Damasceno Humberto , Teixeira João
Published: November 2022

Code smells are bad code structures that can harm the quality and maintainability of software. To remove these bad structures, developers use refactoring techniques. Refactoring helps code be easier to understand and modify by eliminating potential problems and improving the software quality. Most refactoring activities are usually performed manually and undisciplined, which can cause code degradation. Currently, concepts, practices and tools of refactoring and code smells are little discussed in undergraduate computing courses. This problem is reflected in the software industry, which generally does not use refactoring practices to improve code readability and maintainability. In this context, we present in this paper an experience report on teaching the practice of code smells refactoring, investigating the following topics: (i) skills acquired in the practice of code smells refactoring, (ii) difficulties encountered in code smells refactoring and (iii) students’ perception of code smells refactoring practices. The study was carried out in two undergraduate classes with 20 students in the course of software quality. Our findings contribute to replicating the practice in other courses that want to delve into code smell refactoring and contribute to the use of refactoring practices and code quality evaluation in the industry.
Workload and Turnover Intention A Case of Fast Food Industry of Quetta
Authors: Ullah Hidayat , Iqbal Anum
Published: November 2022

The aim of this study was to examine the workload impact on turnover intention amongst employees working in the fast food industry of Quetta - Balochistan, Pakistan. As it has been observed in prior studies that turnover intention in the fast food industry is quite high and industries are facing challenges to overcome the phenomena. In this study, workload was found as one of the critical factor that lead to turnover intention. This study used a quantitative research method based on convenience sampling methods. The data was gathered from employees working in fast food restaurants with the assistance of a predesigned questionnaire. The data were analyzed while using SPSS and Smart-PLS in order to find out the relationship between workload and turnover intention. The results of the study revealed that workload significantly associated with the turnover intention. Based on the findings, it is important for restaurant managers to look over such factor to minimize the turnover intention.
Effect of Interactive White Board on Students’ Achievement at Early Grade Level
Authors: Andleeb Nazish
Published: November 2022

This study aimed to evaluate the effectiveness of Interactive Board on the learning and achievement of students. Students and teachers generally perceive interactive White Boards (IWBs) as a positive addition to the classroom learning environment. While there is support for a link between IWBs and students’ motivation toward learning, the relationship between IWBs, students learning, and achievement is still unanswered. Choosing the experimental research approach, this study compared two groups of preschool students. The researcher used a random sampling technique and divided the sample into two groups through a random assignment on the base of the pre-test and called them “Group A” as the Control Group and “Group B” as the Experimental or treatment Group. In “Group A” the researcher did not use IWBs while in “Group B” the researcher herself, used Interactive White Board to teach the subject of English grade Nursery. The results found revealed that the use of an Interactive Whiteboard significantly affected the student’s knowledge at the preschool level as compared to the traditional teaching method. The study recommends the utilization of digital learning through Interactive White Board.
Sailors’ Problems Caused by the COVID-19 Pandemic
Authors: Łapko Aleksandra , Hącia Ewa , Strulak-Wójcikiewicz Roma , Çınar Kevser , Panai Enrico
Published: November 2022

The article aimed to show which of the restrictions and limitations imposed in connection with the pandemic were the most burdensome for the participants of nautical tourism. It presents the opinions of 580 sailors from six countries: Croatia, France, Germany, Italy, Poland, and Turkey. Research has shown that in the 2020 sailing season, sailors have observed many changes in the functioning of the ports, the services available in their area, and the behavior of other sailors. The restrictions introduced by some countries were sometimes very troublesome for tourists - they forced them to change their previous plans and caused a feeling of uncertainty. Among the most burdensome, the respondents considered those that restricted the free crossing of borders. The obtained results are essential for developing nautical tourism and may contribute to rationalizing decisions taken in a crisis.
TRevPAR as Hotels Performance Evaluation Indicator and Influencing Factors in Portugal
Authors: Lima Santos Luís , Malheiros Cátia , Gomes Conceição , Guerra Tânia
Published: November 2022

In a global competition current scenario, measuring the performance of hotels is increasingly important for managers who, to take decisions, need management indicators and tools. The most common operating indicators are occupancy rate and RevPAR (Revenue Per Available Room). The goal of any hotel is to be as profitable as possible, so they must work on increasing revenues and decreasing costs. To increase revenues the focus has been on revenue management practices, and there is already several software that help hoteliers to define the most appropriate price for each customer. Therefore, managers mostly seek to increase accommodation revenue, however from a total revenue management perspective revenue from other departments must also be considered. The TRevPAR (Total Revenue Per Available Room) appears as a more comprehensive indicator that takes into account all hotels revenue sources. The purpose of this research is to study and highlight TRevPAR influence factors, since this information have practical implications in the hotel managers’ decision. This methodology was carried out through the analysis of 948 hotels from 2010 to 2017. The sample was obtained by crossing two databases: SABI platform and Portuguese National Tourism Registry (RNET). The tested determining factors were the hotel's location, size, number of stars and services. An original and exhaustive study in terms of services meets the purpose, thus, the influence on TRevPAR was tested on outdoor and indoor pools, tennis, golf, spa, meeting rooms and restaurants.
The Impacts of CSR of Hotels on the Socio-Economic Development of the South Tongu District of Ghana
Authors: Anokye Christian Okofo Atta , Hajmasy Gyongyi Steinbachne , Raffay-Danyi Agnes
Published: November 2022

Corporate social responsibility (CSR) has become a key strategic initiative of companies in recent years. The relevance of the topic has grown since the outbreak of COVID-19. The study assesses the socio-economic impacts of corporate social responsibility of hotels in Ghana considering the types of corporate social responsibility activities engaged by the hotels, the socio-economic impacts of those CSR activities, and the advantages of CSR to the hotels. This study employed both interviews and questionnaires. Data from four hotels in the Sogakope community was collected through interviews. Four managers of the long-serving hotels in the community were interviewed. As well, a structured questionnaire was administered to the residents of the Sogakope community. Simple random sampling was employed and 157 responses were used for the analysis. Multiple regression analysis was conducted to test the hypotheses. The study revealed that CSR of hotels relates to socio-economic development of communities positively and significantly. There is a direct, positive, and significant relationship between having socio-economic impacts on communities and competitive advantage for hotels. Moreover, CSR strategies and initiatives adopted by the hotels are more geared towards social aspects of the community rather than environmental or economic. This study is one of the few to use both qualitative and quantitative approaches in finding out the socio-economic impacts of CSR on hotels as most previous studies have used either of them. The findings of the study enhance the knowledge of hotel management about the important role that CSR plays in directly and indirectly promoting the hotel’s performance through reputations and recommendations.
Destination Brand Personality: Case Study of the World Heritage Site of Ellora Caves
Authors: Ragde Nagarjun , Ragde Sanchi
Published: November 2022

Globally Tourism is the fastest growing industry for which competitive destinations are trying their best to promote their tourism products by developing appropriate brand strategies for marketing their products. Identification of Brand Personality is one of the strategies where Destination Marketing Organizations (DMOs) are focusing upon. This study aims to explore the brand personality traits of the first world heritage site of India i.e. Ellora caves situated in Aurangabad District of Maharashtra State of India. Though the site is having potential for Tourism, minimal efforts are taken by the stakeholders for branding Ellora. Primary data was collected using interview schedule and questionnaires from 23 tourism stakeholders of Aurangabad region and 90 domestic tourists at Ellora respectively. Factor Analysis is done to reduce the perceived brand personality traits and developing the most relevant ones. Further Cronbach’s Alpha was used for testing the reliability. Factor Analysis is done to reduce the perceived brand personality traits and coming up with the most relevant ones. 18 new traits were identified which were not seen in marketing literature of Ellora like Intelligent, resourceful, Astute, Senile Surest, Shrewd, Hygiene etc. These identified new traits will help to target new segment of tourists like Millennial’s, Eco Tourists etc. The implications of this paper are dual which are related to academic contribution and policy making for the stakeholders relating to branding of Ellora.
SOSYAL MEDYA REKLAMCILIĞI BAĞLAMINDA DENETİM SÜREÇLERİNDE DİKKATE ALINMASI GEREKEN HUSUSLAR
Authors: ARİKAN Nuraydın
Published: November 2022

Sosyal medya reklamcılığının son yıllarda geldiği nokta ve kamu kurumlarında da yoğun şekilde kullanılmaya başlanmasıyla birlikte, bu reklam türünün içinde bulunduğu sürece has bazı yapısal problemleri irdelemeyi amaçlayan bu makale konuyu denetim süreçlerinde uzmanlara yardımcı olabilecek tespitler şeklinde ele almayı hedeflemektedir. Makalede öncelikle sosyal medya reklamcılığı ile ilgili temel bilgilere yer verilmiştir. Daha sonraki bölümde sosyal medya reklamcılığında yaşanması muhtemelen teknik, hukuki, sosyal sorunlar tespit edilmiştir. En son bölümde de tespit edilen bu muhtemel sorun alanlarının denetim alanına etkilerine yönelik çıkarımlar yapılmaya çalışılmıştır.
Đặc điểm tổn thương động mạch vành và thay đổi mức lọc cầu thận sau chụp hoặc can thiệp động mạch vành qua da ở bệnh nhân bệnh thận mạn
Authors: LÊ VĂN THĂNG , PHẠM LÊ MINH , NGUYỄN TUẤN ANH NGUYỄN TUẤN ANH , ĐỖ ĐỨC TUÂN , PHẠM NHẬT MINH , PHẠM MẠNH HÙNG
Published: November 2022

Introduction: Coronary artery disease is the leading cause of death in patients with chronic kidney disease. Despite many advances in diagnosis and treatment, percutaneous coronary intervention in patients with chronic kidney disease remains challenging.Objectives: (1) Describe clinical, subclinical and coronary artery lesions in patients with chronic kidney disease requiring percutaneous coronary angiography at the Vietnam Heart Institute. (2) Evaluation the changes in clinical, laboratory and glomerular filtration rate after coronary angiography or intervention in thesse patients.Subjects and methods: A descriptive prospective study of 59 chronic kidney disease patients assigned to take percutaneous coronary angiography with or without intervention at the Vietnam Heart Institute from August 2020 to October 2021. The study collected and analyzed information of clinical and laboratory characteristics, percutaneous coronary angiography results and changes in renal function after intervention. Result: The average SYNTAX score was 21,9 ± 13,0. Coronary artery lesions accounted for the majority of branches (84.8%), lesions of 1 branch (11.9%). The most common site of injury was the left anterior descending artery (88.1%) followed by the right coronary artery (71.2%) and the circumflex artery (50.8%). The culprit lesions were often complex, type B2 and type C were the most common types (76.2%), followed by type B1 (14.3%), type A (9.5%). The rate of chronic total occlusion was also quitehigh (25.4%), lesions at the bifurcation (25.4%) were less common in left coronary artery (13.6%). 17,3% of patients had complications of acute kidney injury after the intervention, of which the CKD 3 and CKD 4-5 group were accounted for 12.9% and 23.8% of the patients respectively. Of these, 3 patients had to undergo emergency dialysis after the intervention.Conclusion: Coronary artery lesions in patients with chronic kidney disease was often complicated, often with multiple coronary artery lesions and tended to be more severe with the decline of glomerular filtration rate. Percutaneous coronary intervention in patients with chronic kidney disease had safe results in terms of procedures, however, the rate of complications of acute kidney injury was quite high in patients with CKD.
Results of care and treatment of patients after atrial septal defect intervention and some related factors in 2020-2021
Authors: NGUYỄN THỊ THU PHƯƠNG , VŨ HẰNG HẠNH , PHẠM THỊ HỒNG THI PHẠM THỊ HỒNG THI
Published: November 2022

The study was conducted on 108 patients with atrial septal defect (ASD) who indicated ASD occlusion by percutaneous instrument at the Vietnam Heart Institute-Bach Mai Hospital, Hanoi Medical University Hospital, Hanoi Heart Hospital. from December 2020 to September 2021.Objectives: Describe the clinical and paraclinical characteristics, analyze the results of care for patients with atrial septal defect after intervention and related factors.Research Methods: A prospective descriptive study, a longitudinal study.Results: The majority of patients had good clinical results after 1 month of discharge (65.74%). The rate of pulmonary arterial hypertension after intervention was lower in the group with good results, statistically significant compared with the group with poor results. The group with good results had a lower percentage of patients with anemia, statistically significant compared with the group with poor results. The group with good results had a lower rate of complications after the procedure, which was statistically significant compared with the group with poor results. The difference in the rate of completing 5 steps of implementing the medicine and the rate of meeting the health education requirements between the two groups of good and bad results is statistically significant (p < 0.05). There are 3 factors: Pulmonary artery pressure after intervention still increases (≥35 mmHg); anemia; Postprocedural complications were independently associated with the risk of poor outcome 1 month after discharge. The group with satisfactory health education has a higher rate of patient adherence to treatment than the group that does not meet the requirements of health education (p<0.05).Conclusion: The long-term outcomes of patients with ASD occlusion with percutaneous instruments are related to the treatment, care, and health education counseling of nurses.
Current Perspective on Corporate Board Gender Diversity: Evidence from the Czech Republic
Authors:   University of Hradec Kralove, Hamplová Eva , Janeček Václav ,   University of Hradec Kralove, Lefley Frank ,   University of Hradec Kralove
Published: November 2022

Purpose: This article’s primary purpose is to present and analyze the current state of board gender diversity and elaborate on the relatively sparse literature in this field in the Czech Republic, a post-transition Eastern European economy. The described study sought to identify and comment on the theoretical views concerning previous research in other, mainly Western European countries, by highlighting new perspectives on board gender diversity. Design/methodology/approach: The study’s empirical analysis was based on 235 companies domiciled in the Czech Republic with 500 or more employees. We followed a selection protocol consisting of several filters in arriving at our final sample. We initially analyzed the data in relation to (a) the number of employees, (b) organization turnover, and (c) industrial classification. We calculated the mean (μ), standard deviation, (σ), and coefficient of variation (CV) of the data/variances, then tested our hypotheses through χ2, determining the significance through the p-value. Finally, we calculated the board diversity index (DI) for female/male board members. Findings: Our findings showed that the representation of women on corporate boards of Czech Republic companies is well below the European directive target figure of 40%. There is a greater representation of women on supervisory than on statutory boards. Moreover, the research revealed that female directors are more likely to serve on boards of companies in health care, social, wholesale, retail, and administration sectors compared to the construction, manufacturing, transportation, and storage sectors. Furthermore, company turnover also plays a part in board gender diversity. Finally, we highlighted many reasons why the Czech Republic is a fertile ground for the study of board gender diversity. Practical implications: We believe this article will be valuable to senior managers in industry and wider regulatory, corporate governance, and ethical environments, fostering diversity and equality on corporate boards. This article forms a sound foundation for future studies on board gender diversity in the Czech Republic and contributes to the ongoing discussion on any adoption of possible future quota. Originality/value: This research presents a rare insight into the current board gender diversity structure in the Czech Republic, especially because the country is relatively under-researched in the corporate governance and gender diversity literature. Thus, the research adds to the theoretical views concerning earlier research undertaken in other, mainly Western European countries, highlighting new perspectives on board gender diversity.
Towards a sociology of emergency. Epidemics, biorisks, and the society of the Coronavirus
Authors: Seebach Swen , Beriain Bañares Ana
Published: November 2022

Over the last decade, the social agenda has been shaped by a continuous chain of potentially forthcoming future emergencies. Imagined, projected, and expected emergencies and crises have affected political and scientific agendas and redefined the pre-planning for risks at a local, national, and global level. Whilst most of these emergencies took place largely on an imaginary stage and never materialised – at least not with significant effects on global society – the COVID-19 pandemic finally made real the imaginary that had been expected and projected for over a decade. This article claims that within the context of an emergency in the making and the consequent social, economic, political, and material crises, sociology and social analysis need to assume new responsibilities by providing answers and perspective to those social developments that are direct and indirect results of the social and material conditions of a society of emergency. In a world in which the reality of emergencies has started to outrun the prevention of risks, a sociology of emergency is not only a useful but a necessary step in the development of social theory. We suggest that a redefinition of some of those concepts and ideas that marked the sociological agenda of risk society becomes unavoidable. We argue also that reconnection with those issues that had been discarded from the conceptual framework of a society of risk has become absolutely necessary.
An efficient approach to identifying anti-government sentiment on Twitter during Michigan protests
Authors: Nguyen Hieu , Gokhale Swapna
Published: November 2022

Trust in the government is an important dimension of happiness according to the World Happiness Report (Skelton, 2022). Recently, social media platforms have been exploited to erode this trust by spreading hate-filled, violent, anti-government sentiment. This trend was amplified during the COVID-19 pandemic to protest the government-imposed, unpopular public health and safety measures to curb the spread of the coronavirus. Detection and demotion of anti-government rhetoric, especially during turbulent times such as the COVID-19 pandemic, can prevent the escalation of such sentiment into social unrest, physical violence, and turmoil. This article presents a classification framework to identify anti-government sentiment on Twitter during politically motivated, anti-lockdown protests that occurred in the capital of Michigan. From the tweets collected and labeled during the pair of protests, a rich set of features was computed from both structured and unstructured data. Employing feature engineering grounded in statistical, importance, and principal components analysis, subsets of these features are selected to train popular machine learning classifiers. The classifiers can efficiently detect tweets that promote an anti-government view with around 85% accuracy. With an F1-score of 0.82, the classifiers balance precision against recall, optimizing between false positives and false negatives. The classifiers thus demonstrate the feasibility of separating anti-government content from social media dialogue in a chaotic, emotionally charged real-life situation, and open opportunities for future research.
Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
Authors: Masood Mehar , Masood Madahiah Bint E , Us Subah Noor , Shabbir Maria , Paracha Rehan Zafar , Rafiq Mehak
Published: November 2022

Background

Breast cancer is the second leading cause of cancer-related deaths globally, and its prevalence rates are increasing daily. In the past, studies predicting therapeutic drug targets for cancer therapy focused on the assumption that one gene is responsible for producing one protein. Therefore, there is always an immense need to find promising and novel anti-cancer drug targets. Furthermore, proteases have an integral role in cell proliferation and growth because the proteolysis mechanism is an irreversible process that aids in regulating cellular growth during tumorigenesis. Therefore, an inactive rhomboid protease known as iRhom2 encoded by the gene RHBDF2 can be considered an important target for cancer treatment. Speculatively, previous studies on gene expression analysis of RHBDF2 showed heterogenous behaviour during tumorigenesis. Consistent with this, several studies have reported the antagonistic role of iRhom2 in tumorigenesis, i.e., either they are involved in negative regulation of EGFR ligands via the ERAD pathway or positively regulate EGFR ligands via the EGFR signalling pathway. Additionally, different opinions suggest iRhom2 mediated cleavage of EGFR ligands takes place TACE dependently or TACE independently. However, reconciling these seemingly opposing roles is still unclear and might be attributed to more than one transcript isoform of iRhom2.

Methods

To observe the differences at isoform resolution, the current strategy identified isoform switching in RHBDF2 via differential transcript usage using RNA-seq data during breast cancer initiation and progression. Furthermore, interacting partners were found via correlation and enriched to explain their antagonistic role.

Results

Isoform switching was observed at DCIS, grade 2 and grade 3, from canonical to the cub isoform. Neither EGFR nor ERAD was found enriched. However, pathways leading to TACE-dependent EGFR signalling pathways were more observant, specifically MAPK signalling pathways, GPCR signalling pathways, and toll-like receptor pathways. Nevertheless, it was noteworthy that during CTCs, the cub isoform switches back to the canonical isoform, and the proteasomal degradation pathway and cytoplasmic ribosomal protein pathways were significantly enriched. Therefore, it could be inferred that cub isoform functions during cancer initiation in EGFR signalling. In contrast, during metastasis, where invasion is the primary task, the isoform switches back to the canonical isoform.
Combined transcriptome and proteome analysis of yak PASMCs under hypoxic and normoxic conditions
Authors: Zhang Lan , Zhang Yiyang , Zhou Juan , Yao Yifan , Li Rui , Zhou Manlin , Chen Shuwu , Qiao Zilin , Yang Kun
Published: November 2022

Background

Yaks are animals that have lived in plateau environments for generations. Yaks can adapt to the hypoxic plateau environment and also pass this adaptability on to the next generation. The lungs are the most important respiratory organs for mammals to adapt to their environment. Pulmonary artery smooth muscle cells play an important role in vascular remodeling under hypoxia, but the genetic mechanism underpinning the yak’s ability to adapt to challenging plateau conditions is still unknown.

Methods

A tandem mass tag (TMT) proteomics study together with an RNA-seq transcriptome analysis were carried out on pulmonary artery smooth muscle cells (PASMCs) that had been grown for 72 hours in both normoxic (20% O2) and hypoxic (1% O2) environments. RNA and TP (total protein) were collected from the hypoxic and normoxic groups for RNA-seq transcriptome sequencing and TMT marker protein quantification, and RT-qPCR validation was performed.

Results

A total of 17,711 genes and 6,859 proteins were identified. Further, 5,969 differentially expressed genes (DEGs) and 531 differentially expressed proteins (DEPs) were identified in the comparison group, including 2,924 and 186 upregulated genes and proteins and 3,045 and 345 down-regulated genes and proteins, respectively. The transcriptomic and proteomic analyses revealed that 109 DEGs and DEPs were highly positively correlated, with 77 genes showing the same expression trend. Nine overlapping genes were identified in the HIF-1 signaling pathway, glycolysis / gluconeogenesis, central carbon metabolism in cancer, PPAR signaling pathway, AMPK signaling pathway, and cholesterol metabolism (PGAM1, PGK1, TPI1, HMOX1, IGF1R, OLR1, SCD, FABP4 and LDLR), suggesting that these differentially expressed genes and protein functional classifications are related to the hypoxia-adaptive pathways. Overall, our study offers abundant data for further analysis of the molecular mechanisms in yak PASMCs and their adaptability to different oxygen concentrations.
Scaredy-cats don’t succeed: behavioral traits predict problem-solving success in captive felidae
Authors: O’Connor Victoria L. , Vonk Jennifer
Published: November 2022

Behavioral traits can be determined from the consistency in an animal’s behaviors across time and situations. These behavioral traits may have been differentially selected in closely related species. Studying the structure of these traits across species within an order can inform a better understanding of the selection pressures under which behavior evolves. These adaptive traits are still expected to vary within individuals and might predict general cognitive capacities that facilitate survival, such as behavioral flexibility. We derived five facets (Flexible/Friendly, Fearful/Aggressive, Uninterested, Social/Playful, and Cautious) from behavioral trait assessments based on zookeeper surveys in 52 Felidae individuals representing thirteen species. We analyzed whether age, sex, species, and these facets predicted success in a multi access puzzle box–a measure of innovation. We found that Fearful/Aggressive and Cautious facets were negatively associated with success. This research provides the first test of the association between behavioral trait facets and innovation in a diverse group of captive felidae. Understanding the connection between behavioral traits and problem-solving can assist in ensuring the protection of diverse species in their natural habitats and ethical treatment in captivity.
Recovery of sweet taste preference in adult rats following bilateral chorda tympani nerve transection
Authors: Padalhin Andrew , Abueva Celine , Park So Young , Ryu Hyun Seok , Lee Hayoung , Kim Jae Il , Chung Phil-Sang , Woo Seung Hoon
Published: November 2022

Background

Numerous studies have noted the effect of chorda tympani (CT) nerve transection on taste sensitivity yet very few have directly observed its effects on taste receptor and taste signaling protein expressions in the tongue tissue.

Methods

In this study, bilateral CT nerve transection was performed in adult Sprague Dawley rats after establishing behavioral taste preference for sweet, bitter, and salty taste via short term two-bottle preference testing using a lickometer setup. Taste preference for all animals were subsequently monitored. The behavioral testing was paired with tissue sampling and protein expression analysis. Paired groups of CT nerve transected animals (CTX) and sham operated animals (SHAM) were sacrificed 7, 14, and 28 days post operation.

Results

Immunofluorescence staining of extracted tongue tissues shows that CT nerve transection resulted in micro-anatomical changes akin to previous investigations. Among the three taste qualities tested, only the preference for sweet taste was drastically affected. Subsequent results of the short-term two-bottle preference test indicated recovery of sweet taste preference over the course of 28 days. This recovery could possibly be due to maintenance of T1R3, GNAT3, and TRPM5 proteins allowing adaptable recovery of sweet taste preference despite down-regulation of both T1R2 and Sonic hedgehog proteins in CTX animals. This study is the first known attempt to correlate the disruption in taste preference with the altered expression of taste receptors and taste signaling proteins in the tongue brought about by CT nerve transection.
Startups de gestão de pessoas no Brasil: um estudo exploratório sobre os seus propósitos e as soluções ofertadas
Authors: Medeiros das Chagas Melina , Costa Débora Vargas Ferreira , Paradela Victor Cláudio
Published: November 2022

O desenvolvimento do mercado de startups é uma realidade nacional e internacional, e as startups de RH também estão inseridas nesse contexto, fruto das práticas de empreendedorismo e inovação. O objetivo desta pesquisa consiste em analisar as possibilidades de atuação das startups de gestão de pessoas no Brasil. Para suportar o objetivo, utilizou-se no referencial teórico, o histórico e a conceituação das startups em geral, a contextualização das startups de RH e práticas que envolvem tecnologia no RH. A metodologia utilizada foi uma pesquisa qualitativa, na qual a base de dados foi um relatório realizado em 2019 pela aceleradora brasileira de startups, denominada Liga Ventures, que apresentou 274 startups de recursos humanos. Os resultados obtidos sugerem que os principais subsistemas de RH afetados pelas soluções oferecidas pelas startups de RH são o Recrutamento e Seleção, Treinamento e Desenvolvimento, Remuneração e Monitoramento de Pessoas. Os recursos mais encontrados relacionados a esses subsistemas envolvem People Analytics, plataformas de direcionamento para o público de possíveis candidatos que se deseja alcançar para o processo seletivo, Employee Experience, Employer Branding, inteligência de dados e gamificação para os treinamentos e remuneração, além de softwares com avaliação de performance para as práticas de monitoramento. Além disso, foi detectado que o estado de São Paulo se destaca com a significativa maioria dessas startups. Quanto ao porte, sobressaem-se aquelas que possuem de 11 a 50 funcionários. Verificou-se também que a maior parte das startups pesquisadas tem entre 3 a 4 anos de fundação. Este trabalho contribui para destacar o envolvimento do setor de recursos humanos com recursos tecnológicos por meio das startups de RH e evidencia que as soluções proporcionadas por elas já são uma realidade e possuem grande potencial de desenvolvimento.
Panorama econômico da produção e exportação de mel de abelha produzidos no Brasil
Authors: Trevisol Graciela , Pinheiro Bueno Miriam , Leonardo de Oliveira João Paulo , Macedo Karla Gonçalves
Published: November 2022

O mel, a geleia real e as própolis são produtos provenientes da apicultura. Essas são mercadorias importantes que o Brasil exporta e possui um mercado promissor no exterior.  O mel destaca-se como uma fonte de renda alternativa, pela facilidade de ser desenvolvida em todas as regiões do país, por causa de sua flora diversificada e clima favoráveis, o que contribui para a sua produção durante o ano todo. Este artigo, por meio de pesquisas bibliográficas, teve por objetivo analisar economicamente a produção e a exportação desse produto; considerando o panorama econômico de mel de abelha no país, no período de 2010 - 2020 (dez anos). Os resultados apontam que o Brasil conseguiu se destacar, nos últimos anos, como um dos principais produtores em nível mundial, porém, percebe-se que é possível que o país melhorar ainda mais sua posição no ranking quando aprimorar ainda mais a qualidade na profissionalização do produtor. Portanto, conclui-se que a apicultura brasileira tem potencial para aumentar a sua produção tanto de maneira quantitativa quanto qualitativa, por meio do aperfeiçoamento das técnicas de manejo e adoção de tecnologias adequadas ao seu contexto.
Cooperativas de crédito e desenvolvimento local
Authors: Queiroz Fernanda Cristina Barbosa Pereira , Flach Leonardo , Mattos Luísa Karam de
Published: November 2022

Buscou-se com este artigo mapear a produção científica a respeito das cooperativas de créditos, nas diversas áreas de estudo, presentes nas bases de dados Elsevier’s Scopus e Web of Science (WoS). Utilizou-se o Excel e o RStudio para realizar a análise bibliométrica dos 1365 artigos publicados em 730 fontes recuperados desde 1911. Analisou-se a evolução do número de artigos publicados a respeito das cooperativas de crédito, os periódicos mais relevantes e os autores mais produtivos e citados. Fez-se ainda uma análise dos países com mais citações e um destaque das publicações dos autores das Instituições sediadas no Brasil. Os resultados encontrados indicam que que poucos há pouco que de fato se dedicam a pesquisar a respeito da temática, sendo que a maioria publicou apenas um artigo sobre o assunto, e que um grupo de 57 periódicos é responsável por aproximadamente 33,2% dos artigos publicados. Em relação aos autores do Brasil, verificou-se que o país ocupa a 21ª colocação no total de citações, sendo que apenas 3 artigos publicados são responsáveis por 61% das citações dos artigos nacionais. Há espaço para os pesquisadores internacionais e brasileiros aumentarem a publicação de qualidade sobre a temática, tendo as cooperativas de crédito como objeto de pesquisa em diferentes áreas do conhecimento.
Complexidade tributária brasileira e sua influência na evasão fiscal
Authors: Santos Marcos Vinícius dos , Carvalho Hugo Leonardo Menezes de , Ávila Lucimar Antônio Cabral de
Published: November 2022

O presente estudo teve por objetivo avaliar a relação entre a complexidade tributária brasileira e o nível de evasão do país. Estudos internacionais que já verificaram essa relação não foram conclusivos em seus resultados, apesar de, preponderantemente, os resultados apontarem para uma forte interação entre complexidade e evasão fiscal. A presente pesquisa contribui no país ao testar se a complexidade tributária, enquanto um determinante internacionalmente reconhecido da evasão fiscal, possui influência significativa no nível de sonegação tributária. Para tanto, utilizou-se de modelo de regressão linear múltipla, seguindo o método já utilizado em estudos internacionais, com uma amostra de dados de evasão fiscal, complexidade tributára, carga tributária e percepção de corrupção captadas no Fundo Monetário Internacional, Banco Mundial e Transparência Internacional, no período de 2005 a 2015. Os resultados revelaram que a complexidade tributária não apresentou significância estatística para explicar o comportamento da evasão fiscal brasileira, fato divergente da teoria clássica a respeito da intereção entre essas variáveis. Além disso, observou-se que a carga tributária foi o único determinante no nível de evasão da amostra tratada. Com isso, o estudo apresenta que o tratamento da complexidade tributária brasileira talvez não tenha a dimensão que se é comumente idealizada quando associam a sua participação no contexto de evasão fiscal. Desta forma, o trabalho inaugura os estudos empíricos sobre complexidade tributária brasileira, permitindo que dados do Brasil possam ser melhor conhecidos e debatidos por acadêmicos, governos e empresas na melhoria do conexto tributário nacional.