Supplementary Tables S1-6, Figures S1-2 from Network-Based Integration of GWAS and Gene Expression Identifies a <i>HOX</i>-Centric Network Associated with Serous Ovarian Cancer Risk
Authors: Kar Siddhartha P. , Tyrer Jonathan P. , Li Qiyuan , Lawrenson Kate , Aben Katja K.H. , Anton-Culver Hoda , Antonenkova Natalia , Chenevix-Trench Georgia , Baker Helen , Bandera Elisa V. , Bean Yukie T. , Beckmann Matthias W. , Berchuck Andrew , Bisogna Maria , Bjørge Line , Bogdanova Natalia , Brinton Louise , Brooks-Wilson Angela , Butzow Ralf , Campbell Ian , Carty Karen , Chang-Claude Jenny , Chen Yian Ann , Chen Zhihua , Cook Linda S. , Cramer Daniel , Cunningham Julie M. , Cybulski Cezary , Dansonka-Mieszkowska Agnieszka , Dennis Joe , Dicks Ed , Doherty Jennifer A. , Dörk Thilo , du Bois Andreas , Dürst Matthias , Eccles Diana , Easton Douglas F. , Edwards Robert P. , Ekici Arif B. , Fasching Peter A. , Fridley Brooke L. , Gao Yu-Tang , Gentry-Maharaj Aleksandra , Giles Graham G. , Glasspool Rosalind , Goode Ellen L. , Goodman Marc T. , Grownwald Jacek , Harrington Patricia , Harter Philipp , Hein Alexander , Heitz Florian , Hildebrandt Michelle A.T. , Hillemanns Peter , Hogdall Estrid , Hogdall Claus K. , Hosono Satoyo , Iversen Edwin S. , Jakubowska Anna , Paul James , Jensen Allan , Ji Bu-Tian , Karlan Beth Y. , Kjaer Susanne K. , Kelemen Linda E. , Kellar Melissa , Kelley Joseph , Kiemeney Lambertus A. , Krakstad Camilla , Kupryjanczyk Jolanta , Lambrechts Diether , Lambrechts Sandrina , Le Nhu D. , Lee Alice W. , Lele Shashi , Leminen Arto , Lester Jenny , Levine Douglas A. , Liang Dong , Lissowska Jolanta , Lu Karen , Lubinski Jan , Lundvall Lene , Massuger Leon , Matsuo Keitaro , McGuire Valerie , McLaughlin John R. , McNeish Iain A. , Menon Usha , Modugno Francesmary , Moysich Kirsten B. , Narod Steven A. , Nedergaard Lotte , Ness Roberta B. , Nevanlinna Heli , Odunsi Kunle , Olson Sara H. , Orlow Irene , Orsulic Sandra , Weber Rachel Palmieri , Pearce Celeste Leigh , Pejovic Tanja , Pelttari Liisa M. , Permuth-Wey Jennifer , Phelan Catherine M. , Pike Malcolm C. , Poole Elizabeth M. , Ramus Susan J. , Risch Harvey A. , Rosen Barry , Rossing Mary Anne , Rothstein Joseph H. , Rudolph Anja , Runnebaum Ingo B. , Rzepecka Iwona K. , Salvesen Helga B. , Schildkraut Joellen M. , Schwaab Ira , Shu Xiao-Ou , Shvetsov Yurii B. , Siddiqui Nadeem , Sieh Weiva , Song Honglin , Southey Melissa C. , Sucheston-Campbell Lara E. , Tangen Ingvild L. , Teo Soo-Hwang , Terry Kathryn L. , Thompson Pamela J. , Timorek Agnieszka , Tsai Ya-Yu , Tworoger Shelley S. , van Altena Anne M. , Van Nieuwenhuysen Els , Vergote Ignace , Vierkant Robert A. , Wang-Gohrke Shan , Walsh Christine , Wentzensen Nicolas , Whittemore Alice S. , Wicklund Kristine G. , Wilkens Lynne R. , Woo Yin-Ling , Wu Xifeng , Wu Anna , Yang Hannah , Zheng Wei , Ziogas Argyrios , Sellers Thomas A. , Monteiro Alvaro N.A. , Freedman Matthew L. , Gayther Simon A. , Pharoah Paul D.P. 
Published: March 2023

<p>Supplementary Tables S1-6, Figures S1-2. Supplementary Table S1: Summary of serous EOC GWAS data sets; Supplementary Table S2: Genes in the six significant co-expression networks; Supplementary Table S3: GSEA results after LD-based clumping of SNPs; Supplementary Table S4: GSEA results for the replication data set (COGS); Supplementary Table S5: GSEA results for all networks with > 10 genes; Supplementary Table S6: Number of intragenic SNPs and genes covered by SNPs in the different analyses; Supplementary Figure S1: Q-Q plots of the minimum P-value among all SNPs in each gene with and without the modified Sidak correction; Supplementary Figure S2: Disease Association Protein-Protein Link Evaluator (DAPPLE) protein-protein interaction network</p>