bluuebunny/crossref_metadata_2025 huggingface dataset:
Plasma Biomarkers to Predict Cardiovascular Outcome in Patients With Peripheral Artery Disease
Authors: Kremers Bram , Wübbeke Lina , Mees Barend , ten Cate Hugo , Spronk Henri , ten Cate-Hoek Arina
Published: July 2020

Objective:

Patients with lower extremity peripheral artery disease (PAD) are at increased risk of major adverse cardiovascular events. Numerous plasma biomarkers have been investigated in lower extremity PAD, but none are used for clinical risk assessment. We aimed to provide a comprehensive overview of biomarker testing in PAD as a first step to improve risk stratification.

Approach and Results:

A systematic literature review in MEDLINE/PubMed, Cochrane, and Embase was performed, identifying all studies investigating plasma biomarkers in association with cardiovascular events and mortality in lower extremity PAD. Forty-seven studies comprising 21 473 PAD patients met our criteria and were included. Effect estimates were provided by the studies based on a minimum follow-up of 1 year. Meta-analyses were performed by pooling studies per biomarker for each end point. Patients with increased high-sensitivity CRP (C-reactive protein) levels had a relative risk of 1.86 (1.48–2.33) for major adverse cardiovascular events and a relative risk of 3.49 (2.35–5.19) for mortality. Increased fibrinogen and
d
-dimer levels were associated with an increased relative risk of mortality of 2.08 (1.46–2.97) and 2.22 (1.24–3.98), respectively. Additionally, patients with increased NT-proBNP (N-terminal pro-B-type natriuretic peptide) and high-sensitivity cTnT (cardiac troponin T) levels were at an even higher risk of mortality with relative risks of 4.50 (2.98–6.81) and 3.33 (2.70–4.10), respectively.

Conclusions:

This systematic review identifies promising biomarkers representing different pathophysiological processes implicated in lower extremity PAD, including high-sensitivity CRP, neutrophil-lymphocyte ratio, fibrinogen,
d
-dimer, NT-proBNP, and high-sensitivity cTnT. Clinical implementation should be preceded by a management study to test the utility of a combination of these markers for individual risk stratification. Ultimately, this may contribute to tailored treatment and increased effectiveness of current treatment strategies in PAD.
An Intelligence Test Series for Blind and Low Vision Children
Authors: Dekker R. , Drenth P.J.D. , Zaal J.N. , Koole F.D.
Published: July 2020

An intelligence test for blind and low vision children—aged 6 to 15 years—has been constructed. Based on a short vision test, two groups of braille educated children were distinguished: children without usable vision and children with usable vision. No blindfold is used in this test. This article summarizes the results of different types of statistical analyses. Within this framework, more detailed quantitative research can be interpreted. The subtests appear to be highly reliable, and achievement in school can be predicted with some accuracy. Factor analysis indicates four interpretable factors in both vision groups. The vision groups—for which separate age-norms were established—differed mainly on tests measuring spatial ability.
Digital Voice Indexing for Professional Studios
Authors: Van Schyndel A.J.
Published: July 2020

A self-contained voice-indexing system using digital recording techniques was developed in 1981 to provide high-quality voice indexing in a studio environment. One goal was to design a simple operating procedure that would not require a technician. A major revision has resulted in a prototype second-generation digital voice indexer. The original design concepts are described, as well as improvements in the new prototype.
Profiles of On-the-Job Accommodations Needed by Professional Employees who are Blind
Authors: Rumrill P.D. , Schuyler B.R. , Longden J.C.
Published: July 2020

This article presents five case studies of professional employees who are blind and the postemployment accommodations they needed in four areas: worksite accessibility, performance of essential job functions, job mastery, and job satisfaction. It also describes the Work Experience Survey, a practical assessment instrument that can be used to engage employees who are visually impaired or blind in identifying and removing barriers to maintaining and advancing their careers.
Do Depression and Binge Drinking Explain the Increased Risk of Sexual Violence Among Sexual Minority Middle and High School Girls?
Authors: Edwards Katie M. , Waterman Emily A. , Banyard Victoria L.
Published: July 2020

Sexual violence (SV) occurs at rates higher among sexual minority youth than heterosexual youth, but the mechanisms explaining this higher risk are understudied. We examined if binge drinking and depression explain the higher rates of SV victimization among sexual minority middle and high school girls. Female students ( N = 1,145) in Grades 7th to 10th completed a survey that assessed for SV, binge drinking, depression, sexual orientation identification, and sex at birth. Sexual minority girls had higher rates of SV victimization compared with heterosexual girls. Binge drinking and depression fully mediated the relationship between sexual orientation status and SV victimization among girls. SV prevention programming for sexual minority girls are urgently needed. Programs that seek to reduce binge drinking and depression may be especially impactful in reducing the risk of violence among sexual minority girls.
Numerical and experimental thermal performance with entropy generation analysis on tube with helical screw tape inserts at number of strips in turbulent flow
Authors: Chaurasia Shashank Ranjan , Sarviya RM
Published: July 2020

In the heat exchangers, twisted tape insert is a technique to enhance heat transfer. In this paper, the experimental and numerical investigations are arranged to analyze thermal performance with entropy generation analysis on single and double strip helical screw tape inserts. The finite volume method is used with shear stress transport K-ω model to analyze fluid flow in tube with inserts. The Nusselt number attained enhancement with double strip as compared to single strip helical screw inserts at decreased values of twist ratio and increased values of Reynolds number. However, the Nusselt number attained maximum enhancement of 112% with double strip helical screw insert than plain tube at 4000 of Reynolds number (Re). The common correlations for Nusselt number and friction factor are generated with respect to Reynolds number, number of the strips and twist ratio. Entropy generation analysis is also performed. The thermal performance factor attained its enhancement with double strip than single strip helical screw inserts at twist ratio of 2.5 and 3; whereas, double strip helical screw insert attained maximum value of 1.5 at twist ratio of 2.5 and Reynolds number of 16000. The double strip helical screw inserts are suitable for miniaturization of heat exchanger.
Impact of condensation degree of melamine-formaldehyde resins on their curing behavior and on the final properties of high-pressure laminates
Authors: Santos J , Pereira J , Paiva N , Ferra J , Magalhães FD , Martins JM , de Carvalho LH
Published: July 2020

Melamine-formaldehyde is the most common resin used in the production of high-pressure laminates and low-pressure laminates (melamine impregnated paper), due to its properties of durability, good fire, and heat resistance and good moisture resistance. High-pressure laminate is a common choice for horizontal and vertical applications in the construction and furniture industries, thanks to its durability and versatility. The manufacture of such laminates commonly starts with the impregnation of decorative and kraft papers with thermosetting resins and after a drying process, the impregnated paper sheets are bonded together by high pressure and temperature pressing. The aim of this work was to evaluate the influence of the melamine-formaldehyde resins condensation degree after synthesis on high-pressure laminates performance. For that purpose, melamine-formaldehyde resins with different condensation degree were synthetized and characterized. Fourier-transform infrared–attenuated total reflection spectroscopy and dynamic mechanical analysis were used to study the chemical and mechanical cure of melamine-formaldehyde resins. Melamine-formaldehyde condensation degree has shown to have influence on resin pot-life, on characteristic reaction temperatures, on the degree of cross-linking achieved, and finally on the surface quality of high-pressure laminates.
The Performativity of Literature Reviewing: Constituting the Corporate Social Responsibility Literature Through Re-presentation and Intervention
Authors: Gond Jean-Pascal , Mena Sébastien , Mosonyi Szilvia
Published: July 2020

Although numerous books and articles provide toolkit approaches to explain how to conduct literature reviews, these prescriptions regard literature reviewing as the production of representations of academic fields. Such representationalism is rarely questioned. Building on insights from social studies of science, we conceptualize literature reviewing as a performative endeavor that co-constitutes the literature it is supposed to “neutrally” describe, through a dual movement of re-presenting—constructing an account different from the literature, and intervening—adding to and potentially shaping this literature. We discuss four problems inherent to this movement of performativity— description, explicitness, provocation, and simulacrum—and then explore them through a systematic review of 48 reviews of the literature on corporate social responsibility (CSR) for the period 1975 to 2019. We provide evidence for the performative role of literature reviewing in the CSR field through both re-presenting and intervening. We find that reviews performed the CSR literature and, accordingly, the field’s boundaries, categories, and priorities in a self-sustaining manner. By reflexively subjecting our own systematic review to the four performative problems we discuss, we also derive implications of performative analysis for the practice of literature reviewing.
Why Team China suffered its worst performance in artistic gymnastics at Rio 2016?
Authors: He Jun , Montez de Oca Jeffrey , Zhang Lei
Published: July 2020

China’s artistic gymnastics team had its worst showing at Rio since returning to the Games in 1984. This article explains the reasons for China’s underperformance at Rio by drawing on multiple sources of data. We analyze the scores that international gymnasts received at the World Championships and the Olympics. We also draw on interview data of Chinese gymnasts, coaches, and officials. Our study shows that the collapse in Rio primarily resulted from misinterpreting changes in both the new competition system for the team final and the open-ended Code of Points (CoP) introduced by the International Federation of Gymnastics (FIG) after Beijing 2008. The misinterpretation led to poor strategies when preparing for the Rio Olympics. Further, we believe there is something hidden in their defeat that reveals larger developmental trends in international gymnastics. Thus, by addressing China’s downfall at Rio, we identify important developments in international gymnastics such as the increasing importance of all-arounders, the necessity of execution, and extending the careers of both men and women gymnasts. The conclusions we draw from Team China’s failure at Rio 2016 have broader implications for how other gymnastics nations can prepare for international competitions.
KGHC: a knowledge graph for hepatocellular carcinoma
Authors: Li Nan , Yang Zhihao , Luo Ling , Wang Lei , Zhang Yin , Lin Hongfei , Wang Jian
Published: July 2020

Background

Hepatocellular carcinoma is one of the most general malignant neoplasms in adults with high mortality. Mining relative medical knowledge from rapidly growing text data and integrating it with other existing biomedical resources will provide support to the research on the hepatocellular carcinoma. To this purpose, we constructed a knowledge graph for Hepatocellular Carcinoma (KGHC).

Methods

We propose an approach to build a knowledge graph for hepatocellular carcinoma. Specifically, we first extracted knowledge from structured data and unstructured data. Since the extracted entities may contain some noise, we applied a biomedical information extraction system, named BioIE, to filter the data in KGHC. Then we introduced a fusion method which is used to fuse the extracted data. Finally, we stored the data into the Neo4j which can help researchers analyze the network of hepatocellular carcinoma.

Results

KGHC contains 13,296 triples and provides the knowledge of hepatocellular carcinoma for healthcare professionals, making them free of digging into a large amount of biomedical literatures. This could hopefully improve the efficiency of researches on the hepatocellular carcinoma. KGHC is accessible free for academic research purpose at http://202.118.75.18:18895/browser/.

Conclusions

In this paper, we present a knowledge graph associated with hepatocellular carcinoma, which is constructed with vast amounts of structured and unstructured data. The evaluation results show that the data in KGHC is of high quality.
Modelling clinical experience data as an evidence for patient-oriented decision support
Authors: Yang Junyi , Xiao Liang , Li Kangning
Published: July 2020

Background

Evidence-based Clinical Decision Support Systems (CDSSs) usually obtain clinical evidences from randomized controlled trials based on coarse-grained groups. Individuals who are beyond the scope of the original trials cannot be accurately and objectively supported. Also, patients’ opinions and preferences towards the health care delivered to them have rarely been considered. In this regards, we propose to use clinical experience data as an evidence to support patient-oriented decision-making.

Methods

The experience data of similar patients from social networks as subjective evidence and the argumentation rules derived from clinical guidelines as objective evidence are combined to support decision making together. They are integrated into a comprehensive decision support architecture. The patient reviews are crawled from social networks and sentimentally analyzed to become structured data which are mapped to the Clinical Sentiment Ontology (CSO). This is used to build a Patient Experience Knowledge Base (PEKB) that can complement the original clinical guidelines. An Experience Inference Engine (EIE) is developed to match similar experience cases from both patient preference features and patient conditions and ultimately, comprehensive clinical recommendations are generated.

Results

A prototype system is designed and implemented to show the feasibility of the decision support architecture. The system allows patients and domain experts to easily explore various choices and trade-offs via modifying attribute values to select the most appropriate decisions.

Conclusions

The integrated decision support architecture built is generic to solving a wide range of clinical problems. This will lead to better-informed clinical decisions and ultimately improved patient care.
Correction to: Comparing and assessing physical activity guidelines for children and adolescents: a systematic literature review and analysis
Authors: Parrish Anne-Maree , Tremblay Mark S. , Carson Stephanie , Veldman Sanne L. C. , Cliff Dylan , Vella Stewart , Chong Kar Hau , Nacher Maria , del Pozo Cruz Borja , Ellis Yvonne , Aubert Salome , Spaven Billie , Sameeha Mohd Jamil , Zhang Zhiguang , Okely Anthony D.
Published: July 2020

An amendment to this paper has been published and can be accessed via the original article.
Molecular mechanisms of sex bias differences in COVID-19 mortality
Authors: Li Yuchong , Jerkic Mirjana , Slutsky Arthur S. , Zhang Haibo
Published: July 2020

More men than women have died from COVID-19. Genes encoded on X chromosomes, and sex hormones may explain the decreased fatality of COVID-19 in women. The angiotensin-converting enzyme 2 gene is located on X chromosomes. Men, with a single X chromosome, may lack the alternative mechanism for cellular protection after exposure to SARS-CoV-2. Some Toll-like receptors encoded on the X chromosomes can sense SARS-CoV-2 nucleic acids, leading to a stronger innate immunity response in women. Both estrogen and estrogen receptor-α contribute to T cell activation. Interventional approaches including estrogen-related compounds and androgen receptor antagonists may be considered in patients with COVID-19.
Exercise promotes satellite cell contribution to myofibers in a load-dependent manner
Authors: Masschelein Evi , D’Hulst Gommaar , Zvick Joel , Hinte Laura , Soro-Arnaiz Inés , Gorski Tatiane , von Meyenn Ferdinand , Bar-Nur Ori , De Bock Katrien
Published: July 2020

Background

Satellite cells (SCs) are required for muscle repair following injury and are involved in muscle remodeling upon muscular contractions. Exercise stimulates SC accumulation and myonuclear accretion. To what extent exercise training at different mechanical loads drive SC contribution to myonuclei however is unknown.

Results

By performing SC fate tracing experiments, we show that 8 weeks of voluntary wheel running increased SC contribution to myofibers in mouse plantar flexor muscles in a load-dependent, but fiber type-independent manner. Increased SC fusion however was not exclusively linked to muscle hypertrophy as wheel running without external load substantially increased SC fusion in the absence of fiber hypertrophy. Due to nuclear propagation, nuclear fluorescent fate tracing mouse models were inadequate to quantify SC contribution to myonuclei. Ultimately, by performing fate tracing at the DNA level, we show that SC contribution mirrors myonuclear accretion during exercise.

Conclusions

Collectively, mechanical load during exercise independently promotes SC contribution to existing myofibers. Also, due to propagation of nuclear fluorescent reporter proteins, our data warrant caution for the use of existing reporter mouse models for the quantitative evaluation of satellite cell contribution to myonuclei.
Impact of the perioperative inotropic support in grown-up congenital heart patients undergoing cardiac surgery: a propensity score adjusted analysis
Authors: Mauriat Philippe , Bojan Mirela , Soulie Sylvie , Foulgoc Hélène , Tafer Nadir , Ouattara Alexandre
Published: July 2020

Background

Grown-up congenital heart (GUCH) patients represent a growing population with a high morbidity risk when undergoing reparative surgery. A main preoperative feature is right ventricular failure, which represents a risk factor for postoperative low cardiac output syndrome. Levosimendan has a potentially beneficial effect. This retrospective study included consecutive GUCH patients with surgeries in a tertiary cardiothoracic centre between 01-01-2013 and 01-10-2017, to test the hypothesis that the postoperative use of levosimendan might be associated with shorter time of mechanical ventilation, when compared with the use of milrinone. To adjust for bias related to the probability of treatment assignment, it uses the inverse propensity score weighting methodology.

Results

Overall 363 patients had GUCH surgeries during the study period, their mean age was 31.39 ± 15.31 years, 87 patients were eligible for analysis in the Levosimendan group and 117 in the Milrinone group. The propensity score used pre- and intraoperative variables and resulted in a good balance between covariates. The Levosimendan group included patients with higher preoperative risk scores, a higher prevalence of left and right ventricular failure, who required more often the addition of epinephrine, renal replacement therapy, prolonged mechanical ventilation and intensive care stay. However, after propensity score weighting, patients in the Levosimendan group had shorter durations of mechanical ventilation (average treatment effect − 37.59 h IQR [− 138.85 to − 19.13], p = 0.01) and intensive care stay (average treatment effect − 3.11 days IQR [− 10.03 to − 1.48], p = 0.009). The number of days of additional epinephrine support was shorter and the vasoactive inotropic scores lower.

Conclusion

We report a beneficial effect in terms of duration of mechanical ventilation and intensive care stay, and on inotropic requirements of the use of levosimendan following GUCH surgeries. The use of levosimendan in this setting requires validation at a larger scale.
Effect of whole body vibration versus resistive exercise on premenstrual symptoms in adolescents with premenstrual syndrome
Authors: ElDeeb Abeer M. , Atta Hanaa K. , Osman Doaa A.
Published: July 2020

Background

Premenstrual syndrome (PMS) is a cyclic disorder that affects social activities, interpersonal relationship, and educational productivity of adolescents. Therefore, this study aimed to compare the effect of whole body vibration (WBV) and resistive exercise on premenstrual symptoms in adolescents with PMS.

Methods

Sixty adolescents, aged 16–19 years and with body mass index > 19.9 kg/m2, participated in the study. They were randomly assigned to three groups equal in number. Control group received magnesium (Mg) (250 g) and vitamin B6 supplementation once daily. Resistive exercise group received the same supplementations and resistive exercise for three times/week, while the WBV group received the same supplementations and WBV training three times/week for 12 weeks. Premenstrual syndrome questionnaire (PMSQ) was used to evaluate premenstrual symptoms, including anxiety symptoms (PMS-A), depression symptoms (PMS-D), craving symptoms (PMS-C), hyperhydration symptoms (PMS-H), other symptoms, cramp, and low back pain.

Results

Pair-wise comparison test revealed a significant decrease (p= 0.000) in PMS-A, PMS-C, PMS-D, PMS-H, other symptoms, cramp, and low back pain of the resistive exercise group and WBV group after treatment. However, there was only a significant decrease in PMS-C (p= 0.03) of the control group after treatment. Post hoc test showed no significant difference (p> 0.05) between the resistive group and WBV group in all PMS symptoms after treatment.

Conclusions

Passive muscular training using WBV has a similar effect to resistive exercise on premenstrual symptoms that affect the quality of life in adolescents with PMS.

Trial registration

PACTR,PACTR201908589835132. Registered 26 June 2019—retrospectively registered.
Acute Flaccid Myelitis in COVID-19
Authors: Abdelhady Mohamed , Elsotouhy Ahmed , Vattoth Surjith
Published: July 2020

Spinal cord imaging findings in COVID-19 are evolving with the increasing frequency of neurological symptoms among COVID-19 patients. Several mechanisms are postulated to be the cause of central nervous system affection including direct virus neuroinvasive potential, post infectious secondary immunogenic hyperreaction, hypercoagulability, sepsis and possible vasculitis as well as systemic and metabolic complications associated with critical illness. Only a few case reports of spinal cord imaging findings are described in COVID-19, which include transverse myelitis, acute disseminated encephalomyelitis and post-infectious Guillain Barre’ syndrome. We are describing a case of myelitis which, to the best of our knowledge, is the first reported case of myelitis in COVID-19.
Distúrbios osteomusculares e ações para reduzir a ocorrência em trabalhadores de enfermagem
Authors: Silva Silmar Maria da , Braga Natália Teixeira , Soares Rosimeire Ângela de Queiroz , Baptista Patricia Pavan Campos
Published: July 2020

Objetivo: identificar a presença de distúrbios osteomusculares relacionados ao trabalho nos trabalhadores de enfermagem de uma unidade de clínica médica e construir juntos aos trabalhadores propostas para reduzir a ocorrência dos distúrbios osteomuscularesno ambiente de trabalho. Método: estudo transversal com 31 trabalhadores de enfermagem de uma clínica médica, que responderam uma ficha de dados sóciodemográfico e profissional e do Questionário Nórdico de Sintomas Osteomusculares. Resultados: os trabalhadores exercem suas atividades laborais com dores osteomusculares, sendo as regiões corpóreas mais prevalentes a lombar e a porção superior da coluna e ombros. Apesar disso, nem todos se afastam do trabalho ou procuram assistência terapêutica. As ações de redução dos distúrbios osteomusculares levantadas foram categorizadas em três dimensões: indivíduo, equipe e instituição. Conclusão: os trabalhadores apresentam distúrbios osteomusculares, principalmente, nas costas. As ações de redução de sua ocorrência perpassam pelo comportamento individual às mudanças estruturais e provisão de equipamentos de trabalho.
Excitation and emission dual-wavelength confocal metalens designed directly in the biological tissue environment for two-photon micro-endoscopy
Authors: Sun Dongqing , Yang Yanju , Liu Shujing , Li Yang , Luo Mingyan , Qi Xiaoling , Ma Zengguang
Published: July 2020

With the advantages of completely controlling the phase, amplitude, and polarization in subwavelength range, metalenses have drawn intensive attentions in high resolution two-photon micro-endoscopic fluorescence imaging system. However, chromatic dispersion and severe scattering of biological tissue significantly reduce excitation-collection efficiency in the traditional two-photon imaging system based on traditional metalenses designed in the air background. Here, an excitation and emission dual-wavelength confocal and polarization-insensitive metalens designed in the biological tissue environment was proposed by adopting the composite embedding structure and spatial multiplexing approach. The metalens with numerical aperture (NA) of 0.895 can focus the excitation (915 nm) and emission (510 nm) beams to the same focal spot in the mouse cortex. According to the theoretical simulation of two-photon fluorescence imaging, the lateral resolution of the collected fluorescent spots via the proposed metalens can be up to 0.42 µm. Compared to the metalens designed in the air environment, the collection efficiency of fluorescent spot is improved from 5.92% to 14.60%. Our investigation has opened a new window of high resolution and minimally invasive imaging in deep regions of biological tissues.
Politicians and political parties’ use of social media in-between elections
Authors: Graham Todd , Schwanholz Julia
Published: July 2020

Digital transformation changes the relationship between citizens and politics. The observation of this nexus is highly relevant for representative democracy. After the successful 2008 Obama campaign, a vast body of research that explores how and why politicians use social media has emerged. However, we still know very little about how social media are being adopted and used in-between elections, and still less yet about what this means for political representation. Therefore, this special issue brings together innovative research that focuses on how the use of social media is impacting upon the relationship between politicians and political parties, and citizens. First, we discuss some pros and cons of this transformation in the context of the relevant literature and, especially, in relation to Stephen Coleman’s concept of ‘direct representation’. Finally, we discuss the findings and merits of the contributions and what the issue adds to our understanding of the phenomenon to the state of research.
Clinicopathological and molecular profiles of Babesia vogeli infection and Ehrlichia canis coinfection
Authors: Rawangchue Thanakorn , Sungpradit Sivapong
Published: July 2020

Background and Aim: Canine babesiosis, a tick-borne parasitic disease, is caused by the hemoprotozoa, Babesia vogeli, and Babesia gibsoni. Infection with these parasites, which is endemic globally, leads to life-threatening immunosuppression in dogs. The merozoites invade the red blood cells (RBCs) of infected dogs. Ehrlichia canis, an intracellular bacterium that infects monocytes, is transmitted by the same tick species (Rhipicephalus sanguineus) during blood consumption and coinfection with B. vogeli and E. canis has been reported. Although the hematology and biochemistry of canine babesiosis have been studied, more studies are needed to develop a better understanding of the hematobiochemical and molecular profiles associated with cases of single infection and coinfection of canine babesiosis in Thailand. This study aimed to investigate the hematological, biochemical, and molecular profiles of B. vogeli infection and E. canis coinfection. Materials and Methods: The study included 33 B. vogeli–positive blood samples and 11 E. canis–coinfected blood samples. To exclude coinfection with Hepatozoon canis and Anaplasma platys, only dogs with B. vogeli infection and B. vogeli–E. canis coinfection were included in the study. A multiplex polymerase chain reaction (PCR) assay was conducted to detect B. vogeli, E. canis, and H. canis, and a conventional PCR assay was conducted for the detection of A. platys. Besides, the PCR assay and sequencing, comprehensive data analysis was conducted, including a microscopic blood parasite examination and hematological and biochemical data analysis. Results: The comparison of the hematobiochemical data between the B. vogeli–positive and E. canis coinfection groups identified that there were statistically significant differences in the RBC parameters, including RBC count, hemoglobin concentration, hematocrit, and RBC distribution width (p=0.001). Neither B. vogeli infection nor coinfection with E. canis was associated with the sex, breed, recorded clinical signs, geographic origin of the dog and also B. vogeli 18S rRNA gene sequencing results. Conclusion: Coinfection with E. canis increased the severity of babesiosis. The pathogenic mechanisms underlying this infection, such as destruction of RBCs, require further investigation. This study may enhance diagnosis, treatment, and prevention of canine babesiosis.
Российская молодежь и ее роль в трансформации общества
Authors: Петухов Владимир Васильевич
Published: July 2020

В статье анализируются причины актуализации в молодежной среде запроса на перемены, роста ее гражданской активности. Среди них, по мнению автора, помимо экономических и социальных факторов, связанных со сложностями кризисной адаптации, существенную роль играют наметившиеся расхождения между значительной частью современной молодежи и властными элитами в отношении представлений о желаемом будущем России, тех целей, к которым она должна стремиться в ХХI веке. Опираясь на результаты мониторинговых исследований Института социологии ФНИСЦ РАН, автор отмечает, что современная молодежь желаемый образ страны связывает прежде всего с реализацией идей и принципов социальной справедливости и демократии, которые за последние четыре года в молодежной среде приобрели много новых сторонников, особенно в самой младшей возрастной группе (18-24 года). Выросло и число молодых россиян, высказывающихся за прекращение жесткой конфронтации с Западом. И, напротив, идея «возвращения России к национальным традициям, моральным и религиозным ценностям, проверенным временем», сегодня заметно менее популярна в молодежной среде, чем в 2014 г. В целом же можно констатировать, что понимание молодежью ключевых целей общественного развития формируется под влиянием современных реалий, а не воспоминаний о прекрасном, или, напротив, ужасном прошлом. И в этой ситуации молодежь становится общественной стратой, не только заинтересованной в социальных изменениях, но имеющей альтернативный взгляд на приоритеты будущего развития страны.
В то же время, становясь актором запроса на перемены, нынешнее поколение молодежи пока не готово выступать самостоятельным актором политического действия. Прежде всего в силу того, что оно, как и общество в целом, весьма дифференцировано и не обладает необходимой институциональной субъектностью. Тем не менее, не претендуя на лидерские позиции в общественных преобразованиях, молодежь способна стать частью коалиции общественных сил, социальных и политических движений, нацеленных на перемены, ее политически активная часть уже сейчас готова конкурировать с традиционными партиями в части электоральной и шире — политической мобилизации. В рамках же разнообразных гражданских инициатив она способна привлекать внимание общества к новым темам, новым участкам социальных конфликтов, которые мало заботят как государство, так и ключевых политических игроков. Но что представляется наиболее существенным, современная молодежь может задавать не только идейно-политические, но и моральные ориентиры, возвращая в общественный обиход на фоне тотальной «гибридности» и релятивизма понятия нормы — в праве, человеческих взаимоотношениях, морали и т.п., что сегодня является не менее фундаментальной задачей, чем борьба с бедностью, коррупцией, деградацией социальной сферы.
Благодарность. Статья подготовлена при поддержке РФФИ, проект «Социальная трансформация российского общества: акторы запроса на перемены» № 19 011 00277.
Comparative Study of the Thermal Performance of Two Thermosiphon Solar Water Heaters System
Authors: Koua Blaise Kamenan , Koffi Paul Magloire Ekoun , Gbaha Prosper
Published: July 2020

The aim of this study is to present the comparative results of experimental investigations of the thermal performance of two thermosiphon solar water heaters system (SWHS). The first uses the coconut fiber (CF), a local vegetable and the second, the glass wool (GW), an imported and expensive material, as thermal insulations. The maximum instantaneous efficiencies are, respectively, 65.30 % and 58.7% with glass wool and coconut fiber while the mass flow rate values are, respectively, 0.0098 kg/s and 0.0078 kg/s with glass wool and coconut fiber. In addition, the calculated average values of F’(τα) and F’UL are, respectively, 0.79 and 5.86 Wm-2°C for the coconut fiber collector and 0.8 and 5.26 Wm-2°C for the glass wool collector. The average heat exchanger effectiveness obtained for the two SWHS are superior to 50%. As an environment-friendly and renewable material, coconut fiber is particularly suitable for thermal insulation in order to save energy. The experimental results show the ability of the constructed solar water heater in providing hot water suitable for maternity, hotels, households and encourage its implementation and utilization on a broad scale. The SWHS can be used in any weather conditions.
Zapomniani tłumacze starożytnych greckich tragedii
Authors: Bibik Barbara
Published: July 2020

Z licznego, jak się okazuje, korpusu polskich przekładów greckich tragedii powszechnie funkcjonuje zaledwie kilka nazwisk tłumaczy. Na rozpoznanie wciąż czekają kolejni tak dziewiętnasto-, jak i dwudziestowieczni tłumacze. Jako przyczynek do zarysu historii polskiej literatury tłumaczonej chciałabym w niniejszym artykuleskoncentrować się przede wszystkim na tych mniej znanych, dziewiętnastowiecznych tłumaczach starożytnej literatury dramatycznej. Są oni dzisiaj często zapomniani, a przecież torowali drogę starożytnym dramatom w polskiej kulturze w nie mniejszym stopniu niż te zapamiętane, wielkie nazwiska. Dodatkowo chciałabymsię przyjrzeć proponowanym przez nich ówczesnej publiczności tekstom, nie zawsze stanowiącym oczywisty wybór spośród zachowanego korpusu starożytnych tragedii.
Web Forensic on Container Services Using Grr Rapid Response Framework
Authors: Riadi Imam , Umar Rusydi , Sugandi Andi
Published: July 2020

Cybercrime on Internet that keeps increasing does not only take place in the environment that running web applications traditionally under operating system, but also web applications that are running in more advance environment like container service. Docker is a currently popular container service in Linux operating system needs to be secured and implements incident response mechanisme that will investigate web server that was attacked by DDoS in fast, valid, and comprehesive way. This paper discusses the investigation using Grr Rapid Response framework on web server that was attacked by DDoS running in container service on Linux operating system, and the attacker using Windows oprating system that runs DDos script. This research has succesfully investigated digital evidence in the form of log file from web server running on container service and digital evidence through netstat on Windows computer.
Impacto de la comunicación intercultural en la competitividad para las empresas de la industria cervecera en Ciudad Juárez
Authors: Ramos Rubio Patricia , Holguín Villalobos Héctor Francisco
Published: July 2020

El artículo deriva de un estudio basado en la relación entre la comunicación intercultural y la competitividad en la industria cervecera, escrito bajo distintas perspectivas, tanto a nivel empresarial como a nivel cliente, para ofrecer un panorama de la relación constituida por elementos culturales, comunicativos y competitivos, con el objetivo de identificar la influencia de la comunicación intercultural para la competitividad. El trabajo se basa en un método cuantitativo con un enfoque descriptivo, correlacional y parte de la generación de nuevos factores para aumentar la competitividad de las organizaciones, que plantean un nuevo horizonte de soluciones. Los resultados muestran opiniones inversas para la sensibilidad a las actitudes y cambios en las necesidades de los clientes, resultando interesante que los valores culturales de una determinada población son conocimiento esencial para las empresas al enviar mensajes a sus clientes potenciales, además de resultar significativo el uso de estos valores para la producción de nuevos diseños de sus productos. Actualmente, la percepción de la relación entre la comunicación intercultural y la competitividad resulta ser interesante y es evidente que en la industria cervecera es fuerte.
The Classic Lobe Eye Phenotype of Drosophila Is Caused by Transposon Insertion-Induced Misexpression of a Zinc-Finger Transcription Factor
Authors: Son Wonseok , Choi Kwang-Wook
Published: July 2020

Dr osophila Lobe (L) alleles were first discovered ∼100 years ago as spontaneous dominant mutants with characteristic developmental eye defects. However, the molecular basis for L dominant eye phenotypes has not been clearly understood. A previous work reported identification of CG10109/PRAS40 as the L gene, but subsequent analyses suggested that PRAS40 may not be related to L. Here, we revisited the L gene to clarify this discrepancy and understand the basis for the dominance of L mutations. Genetic analysis localized the L gene to Oaz, which encodes a homolog of the vertebrate zinc finger protein 423 (Zfp423) family transcriptional regulators. We demonstrate that RNAi knockdown of Oaz almost completely restores all L dominant alleles tested. Lrev6-3, a revertant allele of the L2 dominant eye phenotype, has an inframe deletion in the Oaz coding sequence. Molecular analysis of L dominant mutants identified allele-specific insertions of natural transposons (roo[ ]L1, hopper[ ]L5, and roo[ ]Lr) or alterations of a preexisting transposon (L2-specific mutations in roo[ ]Mohr) in the Oaz region. In addition, we generated additional L2-reversion alleles by CRISPR targeting at Oaz. These new loss-of-function Oaz mutations suppress the dominant L eye phenotype. Oaz protein is not expressed in wild-type eye disc but is expressed ectopically in L2/+ mutant eye disc. We induced male recombination between Oaz-GAL4 insertions and the L2 mutation through homologous recombination. By using the L2-recombined GAL4 reporters, we show that Oaz-GAL4 is expressed ectopically in L2 eye imaginal disc. Taken together, our data suggest that neomorphic L eye phenotypes are likely due to misregulation of Oaz by spontaneous transposon insertions.
Autonomia do usuário na implementação de práticas integrativas complementares
Authors: Ferraz Ivana Santos , Cardoso Climaco Layres Canuta , Silva de Oliveira Boery Rita Narriman , Yarid Sérgio Donha , Da Silva Sena Edite Lago , Martins Filho Ismar Eduardo
Published: July 2020

Esse estudo teve como objetivo desenvolver uma reflexão bioética acerca da autonomia dos usuários submetidos às Práticas Integrativas Complementares no contexto do Sistema Único de Saúde, à luz da concepção de Bioética da Proteção.  Trata-se de revisão integrativa da literatura com recorte temporal de 2007 a 2017, cuja busca do material ocorreu no mês de abril de 2018, na Biblioteca Virtual em Saúde. Como resultado, foi identificado que a maior parte do material analisado é recente, entre 2010 e 2017, escrita por diferentes profissionais que se preocupam em estudar o tema, em periódicos de nível nacional no idioma português, sendo o interesse predominante entre farmacêuticos e enfermeiros. Foi possível perceber que, na concepção dos usuários, as Práticas Integrativas Complementares investigadas influenciam positivamente na autonomia do usuário. Embora as Práticas Integrativas Complementares sejam consideradas estratégias eficazes na promoção da saúde, surgem desafios ao integrá-las em um contexto onde a biociência domina nos aspectos epistemológicos e culturais. Recomenda-se, assim, que se ampliem as pesquisas sobre Prática Integrativa Complementar, e se invista em metodologias para a sensibilização dos atores envolvidos, visando ampliar a interface com a promoção da saúde, favorecendo a compreensão e a consolidação dessas práticas no cenário do fazer em saúde.
Efetividade de intervenções de enfermagem preventivas de respostas adversas a meio de contraste iodado: protocolo de revisão sistemática
Authors: Dos Reis Presses Augusto Renata Aparecida , Hernandez Xavier Mary Cristina , Appoloni Eduardo Aline Helena
Published: July 2020

O objetivo desta revisão é identificar evidências disponíveis na literatura sobre intervenções de enfermagem preventivas de respostas adversas ao meio de contraste iodado. A questão de pesquisa para esse estudo é a seguinte: “Qual a eficácia das ações de enfermagem preventivas de reações adversas desenvolvidas por pacientes que receberão contraste iodado? ” Baseada nas questões que envolvem a segurança do paciente ao risco de evento adverso. Método: revisão sistemática baseada no protocolo do Joanna Briggs Institute, que prevê a formulação de uma questão norteadora, definição de descritores, participação de dois revisores, definição de critérios de inclusão e exclusão dos estudos, definição de bases de dados eletrônicas, seleção dos estudos, análise crítica dos artigos e síntese dos dados com a recomendação do grau de evidência. Resultados esperados: levantamento de evidências científicas para prevenção de respostas adversas ao meio de contraste iodado, bem como fornecer meios para segurança da assistência de enfermagem radiológica.
Airbrushed Coral Sample Preparation for Organic Stable Carbon and Nitrogen Isotope Analyses v1
Authors: Price James , Smith Alexandria , Dobson Kerri , G Grottoli Andrea
Published: July 2020

This method for separating coral tissues from algal endosymbiont (Symbiodiniaceae) for stable isotope analysis is modified from previously published methods (Hughes et al. 2010). There are three parts to preparing coral samples for stable carbon and nitrogen isotope analysis: 1) airbrush to remove coral tissue and algal cells from skeleton and store at -80 °C until ready to separate, 2) separate the coral tissue from the algal cells through centrifugation and filtering, and 3) dry and pack separated tissues into tin capsules for analysis in a stable isotope ratio mass spectrometer. This method was modified from Hughes et al. (2010) by James Price with the assistance of Alex Smith and Kerri Dobson and with the guidance of Andréa Grottoli at The Ohio State University. Literature Cited Hughes A, Grottoli A, Pease T, Matsui Y (2010) Acquisition and assimilation of carbon in non-bleached and bleached corals. Mar Ecol Prog Ser 420:91–101. doi: 10.3354/meps08866
SOP for populating EBI submission templates (ENA) v1
Authors: Alikhan Nabil-Fareed , Griffiths Emma , Timme Ruth , MacCannell Duncan
Published: July 2020

Guidance on how to populate the extended PHA4GE metadata package for SARS-CoV-2 submissions, maximizing interoperability for covid-19 surveillance.
KTSP TRANSITION TOWARDS 2013 CURRICULUM AT JUNIOR HIGH SCHOOL OF TAMAN DEWASA IBU PAWIYATAN TAMANSISWA, YOGYAKARTA
Authors: Husna US Atik Nidaul , Wijayanti Wiwik
Published: July 2020

All of schools policy will surely reap different reactions. 2013 curriculum which was allegedly reformer of KTSP is now a big question about the success of its implementation. This study aims to describe the process of implementing the curriculum 2013 transition at Junior High School of Taman Dewasa Ibu Pawiyatan Tamansiswa, Yogyakarta. The method of this study was qualitative with the type of case study approach. The results of this study indicate that (1). Curriculum planning involves all relevant stakeholders, including: the principal, deputy head of curriculum, deputy head of students’ affairs, deputy head of facilities and infrastructure, teacher teams and school committees. (2). The implementation of the curriculum was carried out in stages. Starting with applying the 2 013 curriculum in grades 7 and 8, meanwhile grade 9 still uses the KTSP. (3). Evaluation of curriculum has two categories of assessment that come from internal and external schools.  The results describe that 2013 curriculum can be implemented gradually well. The conclusion is transition from KTSP to 2013 curriculum gradually. In the near future, the school will implement the 2013 curriculum thoroughly in every class without leaving the school’s specificity with the values of art, culture and character.
Building Houses by the Rootless People: Youth, Identities, and Education in Hong Kong
Authors: KEVIN HO CHUNG-HIN , HAYES TANG HEI-HANG
Published: July 2020

In this essay, Chung-Hin Kevin Ho, a history education university student in Hong Kong, narrates his search for civic identity. Composed through a process of critical and reflective dialogue with Hayes Tang, the essay describes the tension between Chung-Hin’s Chinese ethnic and cultural identity and the democratic values held by Hong Kongers. As a student, he and his peers had to navigate these competing conceptions of identity in their coursework and examinations. The youth of Hong Kong, including Chung-Hin, have protested against the Chinese government, and have fought to protect the values of Hong Kong. As a future educator, Chung-Hin has advice for the government administrations of both Hong Kong and China: work with Hong Kongers to help them “build their own house.” Chung-Hin argues that if Hong Kong is to become closer to China, it cannot be done through force or propaganda. Further, Chung-Hin contends that education initiatives that change the history curriculum of Hong Kong schools is not enough to bring the youth of the city to heel. Chung-Hin’s experiences, and his own understanding of history education in Hong Kong, have helped him see that the values of Hong Kongers need to be respected if there is any hope of gaining their trust and acceptance. In this timely essay, Chung-Hin highlights how government policies and historical legacies have shaped his personal experience and educational trajectory in Hong Kong, as well as the other students who are a part of the largest youth protest movement in recent memory.
Elementos dogmáticos y probatorios del delito de Feminicidio
Authors: COBA JUEZ AQUILEO ANTONIO , MEJÍA LOZANO ANGIE NATALIA , RODRÍGUEZ ROMERO NOHORA CECILIA , PADILLA GUARDO ANGÉLICA MARÍA , VERA AMAYA TIBERIO
Published: July 2020

Este trabajo tiene como propósito realizar una revisión a nivel teórico, identificando los elementos descriptivos que den sustento al porque se considera el Feminicidio como un delito autónomo. Dicha revisión se desarrollará a través de la determinación de los elementos representativos del tipo penal, por medio del análisis de alguno de los casos de connotación nacional, que aplicó la Ley 1761 de 2015 más conocida como la Ley Rosa Elvira Cely que introdujo al Código Penal el delito de Feminicidio como delito autónomo y estableció las características constitutivas y diferenciadoras del tipo penal, pues facilitó la adecuación típica en las investigaciones llevadas por el ente acusador y de esa manera evita de una otra forma los posibles conflictos de interpretación en la fase oral del proceso penal. Resaltamos la dificultad probatoria que tiene este tipo penal por parte del titular de la acción penal (Fiscalía) respecto al acusado en la fase del juicio.