bluuebunny/crossref_metadata_2025 huggingface dataset:
MYOGRAPHY TECHNIQUE IN INVESTIGATING OROFACIAL MUSCULES IN HEARING-IMPAIRED PATIENTS (LITERATURE REVIEW)
Authors: Sokolohorska-Nykina Yu. K. , Kuroyedova V. D.
Published: January 2022

This article briefly reviews the literature describing the application of electoromyography technique to investigate the muscles of the orofacial region. Muscle characteristics are an indicator of complex functional relationships of the dentofacial system. Disorders of muscle function lead to morphological changes in the normal structure of the teeth and bones of the maxillofacial area, as well as exacerbate existing bite pathologies. Today, the electromyography is considered as the latest, objective, and informative method of functional diagnostics of the dentofacial system. This study is an evidence-based method for diagnosis and evaluation of the treatment outcomes in orthodontics, and guarantees an unbiased and objective analysis of the functional state of the patient's maxillofacial apparatus at different stages: from diagnosis to treatment and after its completion. Interference electromyography, a non-invasive technique, is known as the most commonly applied in various fields of dentistry. In orthodontics, interference electromyography is used to control the remodelling of the coordination relationships between the temporal and masticatory muscles in the treatment of malocclusion. In orthodontics, the mandibular levators are of great importance, especially the masticatory muscle, the temporal muscle, the medial pterygoid muscle, and the lateral pterygoid muscle. The sublingual muscle also plays an important role in determining facial morphology. This muscle is responsible for stretching the tongue. Facial muscles, such as the orbicularis oris muscle, are also very important in orthodontics. In patients with hearing deprivation not all the muscles work, only some facial muscles function during speech. The scientific literature presents quite a few studies on the function of the facial and masticatory muscles in orthodontic patients with hearing deprivation, both in children and adults, indicating a greater activity of the masticatory muscles in such patients. However, there is no single scientific conception about the work of the orbicular oris muscle.
CHANGES IN RETINAL MICROCIRCULATION AFTER RHEGMATOGENOUS MACULA-ON AMD MACULA-OFF RETINAL DETACHMENT ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: A PROSPECTIVE STUDY
Authors: Ivanchenko A.Yu. , Bezkorovayna I. N.
Published: January 2022

Introduction. The aim of the study is to evaluate changes in the vascular density and microcirculation of various retinal layers following successful repair of rhegmatogenous retinal detachment without macular area detachment and with macular area detachment using optical coherence tomography angiography and their impact on postoperative clinical outcomes. Materials and Methods: A total of 33 eyes were included in this prospective consecutive observational study: 15 without macular area detachment affected by without macular area detachment and 18 by rhegmatogenous retinal detachment with macular area detachment. All patients were diagnosed as having primary rhegmatogenous retinal detachment (duration of retinal detachment less than 7 days since the onset) and underwent successful surgical treatment within 72 hours after diagnosis. Superficial, deep capillary plexus, and foveal avascular zone area variations were evaluated by optical coherence tomography angiography and correlated with visual acuity during a one-month follow-up. Results: In the without macular area detachment group, the preoperative vascular density of the whole superficial capillary plexus on affected eyes was lower than that of the fellow eyes (p < 0.05). The whole superficial capillary plexus vascular density and the parafoveal superficial capillary plexus vascular density increased during the follow-up period (p < 0.05); moreover, the higher the preoperative whole superficial capillary plexus and parafoveal superficial capillary plexus vascular density, the better the baseline visual acuity (p < 0.05) was. In the macular-on area detachment group, at the first months after surgery, the larger the foveal avascular zone, the lower the visual acuity was (p < 0.05). Conclusions. Consequently, optical coherence tomography angiography is a non-invasive investigation method that enables to assess retinal microcirculation in patients who have undergone surgical treatment for rhegmatogenous retinal detachment. The use of optical coherence tomography angiography offers a potential explanation for the suboptimal restoration of visual acuity despite anatomical restoration of the macula. In the macula-on group, the preoperative vascular density of the entire superficial capillary plexus affected the preoperative visual acuity and was lower than in healthy eyes, but recovered over time. Without macular area detachment superficial capillary plexus vascular density affected preoperative visual acuity, and it was lower than the fellow eye, but recovered over time. In the with macular area detachment group, a larger foveal avascular area was related to a worse visual acuity.
CHANGES IN MYOCARDIAL BIOELECTRIC ACTIVITY IN PATIENTS WITH PROGRESSIVE MYLTIPLE MYELOMA
Authors: Ostrovskyi V.L. , Skrypnyk I.M. , Maslova G.S.
Published: January 2022

Introduction. Long-termed oncohematological course with periods of progression and remission of multiple myeloma, an increase in the cumulative dose of cytostatic drugs usually lead to a growing risk of chemotherapy-induced cardiotoxicity in patients with high cardiac risks. The aim of this study is to investigate changes in myocardial bioelectric activity of patients with progression of multiple myeloma and concomitant ischemic heart disease. Materials and methods. 42 patients with multiple myeloma were examined. The patients were divided into groups according to presence of concomitant coronary heart disease: І (n=15) included patients with multiple myeloma without concomitant cardiovascular diseases; II (n=27) involved patients with multiple myeloma and concomitant coronary heart disease. The patients were assessed before chemotherapy. We analyzed general and biochemical blood count findings. Based on Holter electrocardiography monitoring findings, we assessed heart rate, PQ interval, corrected QT interval. Results: Grade 3 and 4 of anaemia were detected only in the group of patients with multiple myeloma and concomitant coronary heart disease, in 4 (14,80%) and in 1 (3,70%) patients, respectively. Serum creatinine level above 177 μmol / l was found in 1 (6%) patient in the group I and in 2 (7%) patients in the group II. An inverse correlation was found between creatinine levels and erythrocyte counts in patients with multiple myeloma and concomitant coronary heart disease (R=-0,58, p<0,05). Rhythm disorders were found in 3 (20%) patients with multiple myeloma without cardiovascular diseases and in 8 (29.6%) patients with multiple myeloma with concomitant ischemic heart disease, conduction disorders was found in 5 (33%) patients in group I and in 14 (52%) patients in group II. Tendency in increasing the incidence of myocardial bioelectrical activity has been found out in case of concomitant coronary heart disease.
ROLE OF S-ADEMETIONINE IN PROPHYLAXIS OF CHEMOTHERAPY-INDUCED LIVER INJURY IN PATIENTS WITH CHRONIC LYMPHOPROLIFERATIVE DISORDERS
Authors: Skrypnyk R.І. , Maslova G.S.
Published: January 2022

The chemotherapy for chronic lymphoproliferative disorders is associated with the risk of chemotherapyinduced hepatotoxicity. The objective of this study is to assess the effectiveness of S-ademetionine in the prophylaxis of chemotherapy-induced liver injury in patients with chronic lymphoprolypherative disorders. Materials and methods. The study included twenty-five patients with chronic lymphoprolypherative disorders. The patients were examined before chemotherapy and after three courses of chemotherapy. We assessed the following biochemical markers: the activity of alanine and asparagine aminotransferases, gammaglutamyltranspeptidase, alkaline phosphatase, total bilirubin, total protein, creatinine, and urea. Patients were divided into three groups: І (n=14) included patients, who received chemotherapy only; ІІ (n=16) involved patients who received chemotherapy and S-ademetionine in a dose of 1000 mg/day intravenously for 10 days, and then orally 500 mg twice a day for 20 days; ІІІ (n=20) was a control group including 20 healthy individuals. Results and discussion. During the initial examination, abnormal biochemical liver markers were found in 38,5% (5/13) of the group I patients and in 25% (3/12) of group II patients that pointed out a cholestatic pattern of liver injury. On the second examination hepatotoxic reactions were determined in 76,9% (10/13) of group I patients, and 2 (16,6%) patients in the group II. Administration of S-ademetionine into the course of adjuvant therapy led to statistically significant reduction in the total risk of hepatotoxic reactions (RR=0,21: 95% CI 0,059-0,79; p<0,05) and the increase activity of gammaglutamyl transpeptidase in blood serum (RR=0,21: 95% CI 0,059-0,79; p<0,05). Conclusion. S-ademetionine as a component of adjuvant therapy for patients with chronic lymphoprolipherative disorders, who undergo chemotherapy, provides the effective prevention of hepatotoxic reactions.
PECULIARITIES OF CLINICAL COURSE OF ACUTE CALCULOUS CHOLECYSTITIS
Authors: Churpii V. K.
Published: January 2022

Introduction. Rational approaches to the diagnosis and tactics of surgical treatment of acute cholecystitis have resulted in the cut down in postoperative mortality. Despite the frequent occurrence of acute cholecystitis in everyday practice, interest in the problem of its treatment does not fade. With such an extensive and comprehensive investigation of this issue, the availability of international and national recommendations, nevertheless, there are some unresolved issues, including, in particular, the problem of the treatment of acute calculous cholecystitis, the peculiarities of its diagnosis and clinical course. The aim of the study is to elucidate the peculiarities of the clinical course of acute calculous cholecystitis. Methods. We analyzed the findings of diagnostic procedures of 209 patients who received inpatient treatment for uncomplicated acute calculous cholecystitis at the surgical department of the Malovyskivska Central District Hospital, Kirovograd region, from 2016 to 2021. The age of all patients ranged from 18 to 89 years. Results. Ultrasound examination of the abdominal organs plays an important role in the diagnosis of acute and chronic cholecystitis in everyday practice. The patients indicated a history of attacks of hepatic colic, mechanical jaundice. Having analyzed the anamnesis data, we determined the duration of cholelithiasis and the duration of acute calculous cholecystitis in the participants. The most typical symptom of acute cholecystitis was constant or paroxysmal pain with localization in the right hypochondrium. Conclusions. The course of acute calculous cholecystitis in the patients is characterized by a polymorphic clinical picture, its severity is less pronounced due to the depth of pathomorphological changes in the gallbladder wall. Complications of acute calculous cholecystitis produce a significant impact on the course of the disease, moreover, the severity of the systemic inflammatory reaction and concomitant pathology of the patients ' condition is also predetermined by the presence of concomitant pathology.
USE OF OSTEOPLASTIC MATERIALS TO RESTORE BONE DEFECTS FOLLOWING THE SURGICAL TREATMENT
Authors: Bambuliak A.V. , Kuzniak N.B. , Lopushniak L.Ya. , Dmytrenko R.R. , Boichuk O.M.
Published: January 2022

In recent years, the number of dental surgical operations has been growing rapidly worldwide, and clinicians are facing pressing issue to select and apply osteoplastic materials, which would promote rapid repair of jaw bone defects and relieve symptoms during the post-operative period. With the advancements in the field of dentoalveolar reconstruction, it is of great importance to develop the material for bone restoration, which by its properties would be identical to autologous bone. The aim of this study is to analyze the effectiveness of osteoplastic materials used for the augmentation following sinus lift, tooth socket preservation, osteosynthesis of mandibular fractures and extraction of impacted third molars. 280 people aged from 18 to 55 with partial or complete adentia and atrophy of the alveolar arch of the jaws, with chronic periapical infection, chronic generalized periodontitis, fractures and impacted third molars were examined at the Department of Surgical Dentistry and Maxillofacial Surgery of the Chernivtsi Regional Clinical Hospital. All patients were planned to undergo prosthodontic treatment assisted by dental implants. The study has demonstrated that the patients of subgroups B of all groups of the study, where the augmentation of bone defects was performed using a combination of osteoplastic material «Colapan-L» containing multipotent mesenchymal stem cells of adipose tissue and platelet-rich plasma presented alleviating clinical symptoms including pain, collateral oedema, hyperaemia of the oral mucosa and better bone regeneration at the site of surgery, compared with subgroups A, where the augmentation was performed with osteoplastic material «Colapan-L», and sub-groups B, whose healing followed by blood clot forming. The use of osteoplastic materials containing multipotent mesenchymal stem cells of adipose tissue during dental operations improves the regenerative and reparative properties of bone tissue, facilitates the postoperative period and reduces the duration of inpatient treatment period.
An Improved Clustering Using by Likely Attributable Function and Informed Selection in WSN for Science of Management and Engineering
Authors: Nia Tarlan Motamedi , Omidvar Rohollah , Azarm Elham
Published: January 2022

Wireless sensors networks (WSNs) are traditionally composed of large number of tiny homogenous sensors nodes connected through a wireless network that gather data to be treated locally or relayed to the sink node through multi-hop wireless transmission. The low-energy adaptive clustering hierarchy (LEACH) protocol is one of the Famous protocols used in the wireless sensor networks (WSNs). The LEACH protocol in wireless sensor network suffers from many Bugs and many researchers proposed different methods to mitigate them. In this paper, we propose two ideas in a format for improving leach protocol. For Cluster head selection we used a Likely Attributable Function that in this function used from a factor. This factor that we called the informed selection factor helps to farther nodes not selection for cluster head. This significantly decreases the energy consumption and increases the lifetime of associated nodes. Simulation is conducted in using MATLAB results are analyzed for energy consumption.
Вплив багатокомпонентної терапії на діастолічну функцію лівого шлуночка в пацієнтів з резистентною артеріальною гіпертензією
Authors: Matova O. O. , Mishchenko L. А. , Kuchmenko O. B.
Published: January 2022

The aim – to determine prognostic factors of improving left ventricular diastolic function (LV DF) in resistant hypertension (RH) patients (pts) treated with multicomponent antihypertensive therapy during three years.Materials and methods. 102 patients with true RH were included. Patients received triple fixed combination (blocker of the renin-angiotensin-aldosterone system / calcium antagonist / diuretic), to which has been added a fourth drug (spironolactone, eplerenone, moxonidine, torasemide or nebivolol). The state of LV DF was studied at the beginning and at the end of the study. Office and 24-h ambulatory blood pressure (BP) measurements, echocardiography, clinical characteristics, neurohumoral and proinflammatory status were assessed.Results and discussion. Impairment LV DF was detected in 75.5 % of pts. The first degree of LV diastolic dysfunction (DD) was observed in 63.7 %. The patients were divided into 2 groups: the first group included persons without initial impairment of LV DF (n=25), the second – pts with LV DD (n=77). Patients with LV DD were older, had a longer duration of hypertension, higher body mass index, 24-h urinary albumin excretion, office BP and 24-h ambulatory BP, more often (in 2 times) disorders of circadian BP rhythm and concomitant diabetes mellitus (DM). Left ventricular DD in 100 % of cases was associated with severe LV hypertrophy (LVH), increased plasma concentration of inflammatory proteins (CRP, fibrinogen), cytokines (IL-6, TNF-α), increased activity of leukocyte elastase, macrophage matrix metalloproteinase-12. The concentration in the blood of aldosterone, active renin, 24-h urinary excretion of metanephrines did not differ between the groups.Conclusions. Improvement and stabilization of LV DF occurred in parallel with regression of LVH (normalization of LVMI in 35.1 % of pts and significant decrease of LVMI in 64.9 %) against the background of decrease of BP and in the proportion of pts with disturbed circadian BP rhythm. The independent factors of the E/E’ ratio were the initial plasma concentrations of aldosterone (β=0.556; р=0.0001), glucose (β=0.366; р=0.0001), active renin (β=–0.223; р=0.004), 24-h urinary albumin excretion (β=0.188; р=0.016), age (β=0,192; р=0,023). The odds of an improvement in LV DF increased by 3.7 times, if the patient with RH had no DM, LVH regression occurred.
ANALYSIS OF RISK FACTORS OF SEXUAL TRANSMITTED INFECTIONS
Authors: Siregar Putra Apriadi , Nasution Fauziah , Nurhayati Nurhayati , Sitorus Muhammad Ancha , Nasution Reni Armayani , Hayati Fitri
Published: January 2022

Sexually transmitted infections (STIs) are a very dangerous problem, especially with the transmission of STIs. The incidence of STIs is still high because people's knowledge of STIs is still low, and people are still ashamed to admit to STI sufferers so that STI cases are still high. The purpose of this study was to determine the analysis of risk factors of sexually transmitted infections in North Sumatera province (secondary data analysis for the 2017 IDHS). This study conducted a secondary data analysis of the 2017 IDHS in North Sumatra Province. This research was conducted on 1717 women of childbearing age in North Sumatra Province.Â This study used the Chi-square test and Prevalent Rate (PR). The results of this study show chi-square analysis results showed a relationship between the source for STI knowledge: health professional (p <0.001), knowledge of the source for STI knowledge: a religious institution (p <0.001), male STI symptoms (p <0.001) with sexual transmitted infections symptoms with a p-value <0.001. A woman of childbearing age who has a partner with STI symptoms has a 26.088 times greater risk of suffering from an STI than a woman of childbearing age whose partner does not have STI symptoms. Sexually transmitted infections (STIs) are related to STI knowledge: health professional, knowledge of the source for STI knowledge: a religious institution, male STI symptoms. Symptoms of STIs in women of childbearing age partners are closely related to the incidence of STIs in women of childbearing age.
PATIENT SATISFACTION ANALYSIS BASED ON SERVICE QUALITY ASSESSMENT AND TRUST IN HEALTH FACILITIES
Authors: Adriansyah Agus Aan , Makki Makki , Setianto Budhi , Saâ€™adah Nikmatus , Lestari Indah , Arindis Pinky Ayu Marsela
Published: January 2022

Health centers have an important role to provide the best service to the community. One of the problems in the outpatient installation of the Tambelangan Health Center is the decrease in the number of patient visits. It is necessary to evaluate the quality of service so that patients put their trust and then reuse the service until they feel satisfied. The purpose of this study was to analyze the effect of service quality and trust on patient satisfaction. This research is included in the type of analytic observational using a cross-sectional approach. The sample size is 100 patients who seek treatment at the outpatient installation of the Tambelangan Health Center. The sampling technique was carried out by systematic random sampling. Data were obtained directly through the perception of the patient's assessment of the perceived service quality, their trust in the facilities and services received and including the satisfaction that the patient felt through the questionnaire instrument. The data obtained were then analyzed using binary logistic regression. The results showed that all patients (86%) stated that the overall dimensions of service quality were good, and almost all patients (81%) stated that they had believed and almost all respondents (84%) stated that they were satisfied with the service at the Outpatient Installation of the Tambelangan Health Center. Furthermore, service quality has a significant effect on patient satisfaction (p-value = 0.022) and trust has a significant effect on patient satisfaction (p-value = 0.006). The conclusion of the study shows that service quality and trust can affect patient satisfaction.
TECHNICAL SKILLS OVERWHELMING SOCIAL SKILLS OF OCCUPATIONAL HEALTH NURSING ON TEACHING METHODS
Authors: Hardy Syaifoel , Tukayo Isak Jurun Hans , Maulana Rijal , Afzal Ridha
Published: January 2022

The teaching of occupational health nursing (OHN) requires an emphasis on which one should be dominant between technical and social domain, as practiced in the industrial healthÂ care services.Â The purpose of this research isÂ determine which skill domain is more dominant between technical and social skills in the OHN teaching-learning system.Â This type of study is quantitative approach with cross-sectional study design. The populations were nursing students, nursing practitioners, and nursing lecturers. The sampling technique is non-probability sampling taken online with a sample size of 130 respondents of Indonesian nurses in Indonesia. The data collection tool used a mixed questionnaire in a Likert Scale based on the Health Belief Model theory. The data were analyzed using the Paired Sample T-Test to see whether the results of this study were dominated by the technical or social skills domain. The validity and reliability test was carried out with a sample of 30 people. They were measured by looking at the r table and the Cronbach alpha value for each questionnaire statement, using the SPSS application with the Pearson Product Moment test.Â The T-Test result of SPSS shows 95 respondents (73.1%), perceived technical skills dominate the OHN work in industry, and 35 respondents (26.9%)Â in social skills, with a p-value of 0.000. In other words, the dominance of technical skills has a very close association to the teaching-learning system.Â The need for technical skills is much more dominant than social skills. OHN teaching needs to have an emphasis on technical skills, not the social domain.
PARENTAL KNOWLEDGE TOWARDS CHILDRENâ€™S DENTAL AND ORAL HYGIENE
Authors: Efzi Agno Elman , Sari Emilda
Published: January 2022

Dental and oral hygiene problem is the leading cause of daily activities disruption in children such as missing school, bad learning concentration, appetite and nutritional intake. Knowledge of dental and oral hygiene should be given at early age in family by the parents. The aim of our work was to determine relationship between parentsâ€™ knowledge and dental hygiene of the SDLB children (children with special needs). We undertook this research with analytical survey. A cross-sectional design was carried out. The sampling method was total sampling namely parents of children with special needs and the children as many as 80 people. Chi-Square test was performed to analyze the data. The results show that the knowledge of parents about dental and oral hygiene is not good (85%), while the dental and oral hygiene in children with special needs is poor (85%). Based on the Chi-Square Test, it produces a p-value of sig (2-sided) = 0.002 in the test, so it can obtain a p-value (probability value) from the test (p = 0.002 < = 0.05) so that HoÂ is rejected. In conclusion, a relationship between parental knowledge and oral hygiene in children with special needs does exist.Â Â
Pelvic congestion syndrome is an interdisciplinary issue
Authors:   Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russian Federation, Antropova E.Yu. , Sharafutdinov B.M. ,   Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russian Federation,   Kazan (Volga Region) Federal University, Kazan, Russian Federation, Mazitova M.I. ,   Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russian Federation, Gaziev E.A. ,   Kazan (Volga Region) Federal University, Kazan, Russian Federation, Khisamieva G.A. ,   Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russian Federation, Shtern V.V. ,   Kazan State Medical Academy — Branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russian Federation
Published: January 2022

This paper discusses an essential interdisciplinary issue, pelvic congestion syndrome (PGS). PGS is a venous disorder with gonadal vein and/or pelvic venous plexus dilation that results in pelvic venous plethora. The authors address PGS prevalence, causes, underlying pathophysiological mechanisms, major clinical manifestations, diagnostic tools, and treatment approaches. Pharmacotherapy (gonadotropin-releasing hormone agonists, danazol, combined oral contraceptives, progestins, phlebotonics, etc.) is the first-line treatment that provides only a temporary effect. Image-guided vascular surgery (embolization, stenting) is of particular importance among surgical interventions. Surgical technique and critical results of the studies on the efficacy of gonadal vein embolization (from 47% to 100%) are described. The paper details major complications of surgical interventions and highlights issues requiring further researches, i.e., the effects on female fertility, predicted full recovery considering compromised somatic and/or gynecological anamnesis. Finally, the importance of timely diagnosis, greater awareness of primary care physicians on the signs and symptoms of this disorder, and a need to refer these women to vascular surgeons are addressed. KEYWORDS: pelvic congestion syndrome, gonadal vein embolization, pelvic pain, May–Thurner syndrome, nutcracker syndrome. FOR CITATION: Antropova E.Yu., Sharafutdinov B.M., Mazitova M.I. et al. Pelvic congestion syndrome is an interdisciplinary issue. Russian Journal of Woman and Child Health. 2021;4(4):346–350 (in Russ.). DOI: 10.32364/2618-8430-2021-4-4-346-350.
Unity of bowel-lung axis and the role of beneficial microbiota in anti-infectious protection
Authors:   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russian Federation, Taranushenko T.E.
Published: January 2022

NIH Human Microbiome Project determined particular attention of the worldwide medical community to the study of the human microbiome and the assessment of the impact of symbiont microorganisms in the development of various (not only gastrointestinal) disorders. Potential interactions between the bowel and lungs (bowel-lung axis) via microbiota that allow for the possible involvement of microorganisms in the development of respiratory diseases are actively debated. This paper reviews studies on the pattern of interactions between bowel and lungs in infectious diseases associated with mucosal inflammation. The association between gut microbiota and the protective barrier of the respiratory tract based on known mechanisms and novel data derived from recent studies on SARS-CoV-2 is discussed. The relevance of beneficial bacteria (symbionts) in local and systemic immune responses, their disease-modifying and, eventually, therapeutic strategymodifying properties, the ability to be a resource of preventive medicine and an orchestrating tool for infections are addressed. Practitioners’ difficulties with probiotics in preventive and treatment schedules for various conditions are highlighted. Finally, the use of probiotics in children with respiratory infections and COVID-19 is uncovered. KEYWORDS: microbiota, microbiome, probiotics, children, mucosal immunity, Bifidobacterium. FOR CITATION: Taranushenko T.E. Unity of bowel-lung axis and the role of beneficial microbiota in anti-infectious protection. Russian Journal of Woman and Child Health. 2021;4(4):355–361 (in Russ.). DOI: 10.32364/2618-8430-2021-4-4-355-361.
Pathogenic pattern of somatic disorders in children with congenital cleft lip and palate in associated connective tissue dysplasia
Authors:   Research Practical Center for Children’s Specialized Medical Care, Moscow, Russian Federation, Neudakhin E.V. , Prityko A.G. ,   Research Practical Center for Children’s Specialized Medical Care, Moscow, Russian Federation, Kugushev A.Yu. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Meshcheryakova T.I. ,   Research Practical Center for Children’s Specialized Medical Care, Moscow, Russian Federation, Suleymanov A.B. ,   Research Practical Center for Children’s Specialized Medical Care, Moscow, Russian Federation
Published: January 2022

In children with cleft lip and palate (CLP), various organ and organ system abnormalities occur under the effect of endogenous (hereditary) and/ or exogenous (resulting in impaired embryogenesis) factors. The community of CLP and multiorgan disorders is accounted for by connective tissue dysplasia (CTD). According to a theory of mesodermal migration, the development of connective tissue is associated with impaired formation and development of mesodermal elements during embryogenesis. Mitochondrial dysfunction accompanied by significant energy metabolism abnormalities with signs of oxidative stress, hypoxia, and acidosis has a crucial role in CTD. Matrix metalloproteinases are actively involved in developing CTD and CLP. Genotyping of gene polymorphism involved in lip and palate morphogenesis is required to predict the risk of congenital CLP in compromised families. This paper addresses data helpful in developing preventive and treatment approaches, predicting and managing children with CLP from an individual and familial viewpoint. KEYWORDS: children, cleft lip and palate, connective tissue dysplasia, mitochondrial dysfunction, matrix metalloproteinases, energetic therapy, L-carnitine. FOR CITATION: Neudakhin E.V., Prityko A.G., Kugushev A.Yu. et al. Pathogenic pattern of somatic disorders in children with congenital cleft lip and palate in associated connective
Description of ΩΩ, Ω(ccc)Ω(ccc), and Ω(bbb)Ω(bbb) Dibaryon States in Terms of a First-Order Hexaquark Mass Formula
Authors: Bevelacqua Joseph
Published: January 2022

Recently discovered tetraquark and pentaquark structures have renewed interest in multiquark states. In the spirit of these results, the masses of postulated hexaquark structures using a first-order mass formula are determined. The hexaquarks model is applied to ΩΩ, ΩcccΩccc, and ΩbbbΩbbb dibaryon states. The first-order model suggests that the ΩΩ, ΩcccΩccc, and ΩbbbΩbbb hexaquarks have masses of 3.53, 9.78, and 28.8 GeV/c2, respectively.
Impacts of the Inclusion of Distributed Generation on Congestion of Distribution Networks and in the Islanding Operation Capability
Authors: Beltrán Gallego Jose David , Castro Montilla Leidy Daniela , Castro Valencia Alexandra , Giraldo Muñoz Camilo Augusto , López García Dahiana
Published: January 2022

The growing demand for electricity in the world has led to power systems having to constantly increase their generation capacity and expand their transmission and distribution systems. Consequently, distributed generation has positioned as a technology able to integrate generation close to consumption centers, freeing up capacity in the transport systems, which can be translated into a deferral of investments in network expansion. Therefore, this paper analyzes the impact of the inclusion of distributed generation in the congestion of a typical distribution network and evaluates the potential of providing the island operation capability ancillary service in a section of the system to identify the possible challenges and benefits that the development of this technical support service could have in typical Colombian distribution networks.
No olvidemos el espíritu de la medida
Authors: Salas Humberto
Published: January 2022

Columna de opinión.
La piedra de tope de nuestra Araucanía
Authors: Salas Humberto
Published: January 2022

Columna de Opinión.
The Quality Effect of Auditing on Tax Compliance: Evidence from Tunisian Context
Authors: Soltani Lynda
Published: January 2022

Taxation is the subject of complex and evolving regulations. it has become one of the major concerns of any business to better manage its finance, the responsible for corporate governance give an importance to the fiscal in the strategy and management of the company. In recent years, the importance of taxation in the financial and accounting environment is motivated to study the impact of control and transparency of infomation affected by audit quality. We study a sample of 19 companies between 2013 and 2017, the result shows that audit quality improves tax compliance in the Tunisian context while measuring tax evasion by the difference between the statutory tax rate and the effective tax rate. This study finds that tax evasion in Tunisian firms may have decreased with better audit quality.
Investment Risk Tolerance amongst South African University Students in the Vaal Triangle Area
Authors: Evangelou Antonios , Ferreira-Schenk Sune , Ferreira Lorainne , Bothma Elizabeth
Published: January 2022

Analysing students risk tolerance during the investor life cycle is imperative to students and financial planners alike, to facilitate the implementation of suitable investments and investment strategies. Students in universities do not have the required knowledge to invest and this is why an investment framework was created to assist, guide and inform students of what stage of the individual investor life cycle that they are in and suggest suitable investment strategies. The article implemented a quantitative approach, using secondary data analysis. The data used for the analysis is from a self-administered questionnaire in 2017 that was distributed to a sample of 396 students from two higher education institutions in the Vaal Triangle region. Two validated risk tolerance scales were used to analyse students risk tolerance levels. The objective of this paper was to determine the risk tolerance levels of students in the Vaal Triangle region. The two results from the 13-item scale and the single-item scale for measuring risk tolerance indicated that the students have a medium risk tolerance level.
Determining the Impact of Economic Factors to the Gross Domestic Product in Bangladesh
Authors: Hasan Mostofa Mahmud , Hossain B.M. Sajjad , Sayem Md. Abu
Published: January 2022

Gross Domestic Product (GDP) is believed to be an indicator of a country’s economic condition. Bangladesh’s GDP increased at a pace of 8.15% in fiscal 2018-19 as per the base year 2005-06. By the year 2019, Bangladesh has become the seventh fastest-growing economy in the world. This paper used multiple regression analysis model for the macroeconomic factors. The aim of this study is to measure the effects of macroeconomic factors considering GDP as the dependent variables and inflation rate, import, and export are considered as independent. This paper represents that import and export are positively associated factors with GDP whereas inflation rate is a negatively associated factor. This study concluded with revealing the importance of conducting further study by considering more economic variables to measure the economic growth as a whole.
Desain Pengembangan Sistem Pembangkit Listrik Tenaga Gelombang Laut Berbasis Keseimbangan Gyroscope
Authors: Suprapto Bhakti Yudho
Published: January 2022

Indonesia sebagai negara maritim yang luas memiliki potensi sumber energi terbarukan yang berasal dari laut. Dengan memanfaatkan gelombang laut sebagai energi, pembangkit listrik tenaga gelombang laut (PLTGL) dapat menghasilkan tegangan listrik yang cukup untuk memberikan suplai ke peralatan listrik. Selama ini gelombang merupakan permasalahan karena sangat tergantung pada besar kecilnya angin sehingga mempengaruhi tenaga listrik yang dihasilkan. Oleh karena itu pada penelitian ini dikembangkan Sistem Pembangkit Listrik Tenaga Gelombang Laut yang berbasis keseimbangan gyroscope. Pada artikel ini fokus pembahasan pada pengaruh gerakan rotasi gimbal terhadap power take off (PTO) generator. Pergerakan dari flywheel yang berputar akan memberikan momentum kepada gimbal untuk dapat berotasi. Berdasarkan simulasi numerik interaksi antara gimbal dan PTO generator akan menghasilkan tegangan listrik. Hasil yang didapatkan dari percobaan akan mendukung analisa teoritis dan simulasi, serta sebagai acuan untuk membuat desain PLTGL yang memiliki pengendali berkinerja tinggi.
Impact of Multi-metal Mixture Administration Through Drinking Water on the Gut Bacterial Microflora and Oxidative Stress Parameters in Male and Female Mice
Authors:   Department of Bioscience and Biotechnology, Banasthali Vidyapith, Rajasthan, India., Bist Priyanka , Choudhary Sangeeta ,   Department of Bioscience and Biotechnology, Banasthali Vidyapith, Rajasthan, India.
Published: January 2022

Background: Heavy metal containing wastes reaches to the food chain either directly or indirectly. These ingested toxic elements manifest direct impact on the gut ecosystem and its overall functioning. The present study explores the alteration in mice gut bacteria on exposure to mixture of toxic heavy metals through drinking water. Methods: Twelve experimental groups of Swiss albino male and female mice were exposed to the metal mixture of varying concentrations. Profiling of gut bacterial flora was done by periodical collection of fecal samples via culture-based technique. Redox status of all experimental animals was analyzed in blood samples collected on the day 30. Results: In comparison to the controls, nearly a 10-fold decline in colony forming units/ml was observed at higher modal concentrations (50× & 100×) at the end of 15 days, but 100-fold reduced bacterial count was recorded following 30 days of dosing. Sex specific significant alteration in the bacteria count and diversity was also observed. Overall experimental results showed a heavy metal dose-dependent decline in bacterial count and loss in diversity. Disturbance in the oxidative stress markers was recorded in response to high dose of metal mixture. In group receiving 100× dose, malondialdehyde levels were increased in the erythrocytes (P<0.05), and all of the other antioxidant parameters were decreased (P<0.05), except for reduced glutathione in both male and female mice. Conclusion: The present work is the first report on the multiple heavy metals induced gut microbiota alterations and its correlation to oxidative stress.
Diagnóstico socioeconómico y de uso del suelo del cantón Quinindé, provincia de Esmeraldas.
Authors: Orellana Rodríguez Karina Narcisa
Published: January 2022

El presente artículo académico se realizó para establecer un diagnóstico socioeconómico y de la utilización del suelo en el cantón Quinindé, que determine las diferentes modificaciones que han ocurrido en los espacios agrícolas del sector a través del tiempo y en consecuencia la construcción de actores sociales. A través de este artículo académico podemos determinar la diversificada utilización del suelo como factor de producción en el cantón y el nacimiento de nuevos y heterogéneos actores sociales. Para la obtención de información de procesos y situaciones que se busca conocer y comprender se realizó un proceso de investigación cuantitativa. A través de fuentes de información directa e indirecta, derivadas de estadísticas oficiales, textos, leyes y libros. Se logró identificar las transformaciones ocurridas en el uso del suelo quinindeño y caracterizar los actores sociales. Se estableció que, el surgimiento de nuevos actores sociales en la dinámica quinindeña, está sujeta a las transformaciones ocurridas en el uso del suelo.
alineación estratégica: revisión de literatura
Authors: Vega Calvas Paulina Alexandra
Published: January 2022

El presente artículo tuvo como propósito desarrollar una revisión del estado del arte de la variable organizacional alineación estratégica, que ha demostrado su trascendencia en el logro de la eficacia de los objetivos corporativos, a través de su asociación positiva con los recursos organizacionales como: las tecnologías de la información, el liderazgo, la cultura organizacional, el talento humano, las capacidades dinámicas, etc. De esta forma, se procedió con el método de revisión sistemática de la literatura en tres etapas: planeación de la revisión, ejecución de la revisión y elaboración de informe de resultados, a través de cuyo procedimiento y mediante el empleo de la técnica comparativa, se seleccionaron estudios relevantes de revistas y artículos científicos de alto impacto especialmente de la base de datos de la Web Of Science, además se utilizó la técnica de la evaluación de los Journals en bases de datos como SJR Scimago. Los resultados determinaron que la alineación estratégica tiene sus raíces en el ámbito empresarial a través de la teoría de la contingencia, que ha sido objeto de múltiples estudios de manera especial en el ámbito de las tecnologías de la información y de la gestión empresarial, y con escaso desarrollo teórico en áreas como la educativa, el sector turístico, el ámbito público, la medicina, la psicología y otras ciencias. Además, se ha revelado la necesidad de profundizar estudios de la alineación estratégica en diferentes contextos organizacionales.
Inconstitucionalidad del artículo 83 la Ley Orgánica de Gestión de la identidad y Datos Civiles que priva a las personas del derecho humano a la identidad
Authors: Sanipatin Mora Gabriela Alexandra
Published: January 2022

Las autoridades, servidoras y servidores públicos del Servicio de Registro Civil, Identificación y Cedulación de Ecuador, están facultados por el Art. 83 de la Ley Orgánica de Gestión de la Identidad y Datos Civiles, cuando se trate de una doble o múltiple inscripción de un mismo acto o hecho del estado civil de las personas, a pesar de que consten con datos distintos, para anular las inscripciones posteriores. Pero estas anulaciones han generado, igualmente, la anulación del derecho humano a la identidad, situación que contraviene los instrumentos internacionales de derechos humanos que lo consagran, como lo son la Declaración Universal de Derechos Humanos y la Convención sobre Derechos Humanos, ambos de la Organización de Naciones Unidas, así como la Constitución de la República y el Código de la Niñez y Adolescencia. 66 del mencionado cuerpo constitucional dispone que el derecho a la identidad personal incluye conservar, desarrollar y fortalecer las características materiales e inmateriales de la identidad, entre ellas la nacionalidad y la   procedencia familiar.                

Las cuales, al anularse la inscripción de nacimiento, desaparecen administrativamente, lo que es inconstitucional al existir un conflicto entre normas de superior e inferior jerarquía, que la propia Constitución de la República resuelve en el inciso 2° de su Art.
Análisis de las políticas públicas en materia educativa en los centros de privación de libertad en Ecuador
Authors: Villarreal Chiriboga Brayan Alexis
Published: January 2022

El objetivo del presente trabajo investigativo fue analizar el acceso de las personas privadas de libertad a la educación como medio para la rehabilitación social y reinserción laboral, después del cumplimiento de la pena. La metodología científica de investigación utilizada fue la documental, analítica y descriptiva, que mediante la técnica de la observación y el análisis estadístico-documental logró recopilar datos informativos sobre las acciones emitidas por las instituciones relacionadas con el sistema carcelario y el sistema nacional de educación en materia de política pública, encaminada a otorgar el derecho a la educación de las personas privadas de la libertad (PPL) como lo determina la Constitución; permitiendo conocer ¿qué políticas públicas garantizan el acceso a la educación en los Centros de Privación de la Libertad del Ecuador?; ¿cuántos presos tienen acceso al servicio educativo de las cárceles?; ¿cuáles fueron las acciones interinstitucionales que motivaron el ingreso de los presos al proceso de aprendizaje continuo?; ¿cuántos docentes por estudiantes PPL son parte del sistema? Desde el ámbito académico se concluye que el eje educativo es el pilar fundamental para alcanzar la verdadera rehabilitación social y el desarrollo laboral; sin embargo, en el país no se ha alcanzado la transformación del sistema de rehabilitación social.
Percepción sobre los componentes de control interno en la empresa familiar
Authors: Puchaicela Viñamagua Danny
Published: January 2022

El sistema de control interno hace referencia a las políticas adaptadas por la administración para cumplir con el objetivo de asegurar la dirección eficiente del negocio, aspecto de importancia en medio de la coyuntura económica que atraviesa el país, por lo que es necesario que las empresas funcionen de manera eficiente y con calidad, a fin de lograr su sostenibilidad. El presente artículo tiene como objetivo analizar el criterio de control interno que mantienen la empresa familiar y que la administración debe fijar al control interno como una herramienta para prevenir y detectar problemas y disminuir riesgos importantes. Para ello se realizó un estudio de carácter no experimental y descriptivo; se planteó un cuestionario de preguntas por cada componente de control en el que se abordan los criterios más importantes de control; posteriormente, se procedió con la evaluación del nivel de confianza y riesgo por cada uno de ellos, relacionando con la parte más importante del control interno y su incidencia dentro de la empresa. Los resultados revelan una confianza por debajo del 46% (media) y riesgo por encima del 54 % (media), resultados que permiten comprender que la empresa familiar carece de control interno eficiente para proporcionar seguridad razonable y desarrollo al cumplimiento de objetivos.
Transferencia de embriones en bovinos en la provincia de Carchi
Authors: Chugá Bastidas Wilson Santiago , Martínez Chugá Rubén Dario , Cerón Villarreal Stalin Mauricio , Játiva Cortez Dagmar Nataly , Chamorro Pantoja Brayan , Chirán Ayala Gladys Yesenia , Balarezo Urresta Luis Rodrigo , Proaño Deleg Miguel Augusto
Published: January 2022

Se evaluó la respuesta superovulatoria y la tasa de concepción al aplicar la técnica no quirúrgica de transferencia de embriones en vaconas, de la finca Santa Clara y San Francisco en la provincia del Carchi. Se eligió una vaca donadora de alto valor genético, la misma que fue sometida a superovulación, mediante la aplicación de un protocolo hormonal durante siete días. A partir del día ocho se inició la aplicación del protocolo para sincronización de celo; al día diez se realizó la inseminación. La selección se efectuó con ocho vaconas que fueron preparadas para que sirvande receptoras; el protocolo de sincronización tuvo una duración de diez días; se programó la aplicación de los protocolos para sincronizar a la donadora con las receptoras. El día quince se procedió a la extracción de los embriones mediante lavado, el mismo día en laboratorio se realizó la selección de los embriones viables, obteniendo como resultado dos con las características de calidad, los mismos fueron preparados y transferidos inmediatamente en las vaconas, que luego del chequeo ginecológico fueron elegidas receptoras: Adela, de la Finca Santa Clara; y Gema, de la Finca San Francisco.