bluuebunny/crossref_metadata_2025 huggingface dataset:
The Transformation of Health Education in A Pandemic Era
Authors: Koçak Tufan Zeliha
Published: July 2021

Higher education was interrupted in many countries due to the COVID-19 outbreak. In countries with infrastructure, distance and remote learning was initiated. While theoretical trainings and lectures are carried out relatively successfully, problems related to applied trainings continue to be discussed. Practical training, clinical internships, and field practices in almost all health programs, especially in medical education, have been suspended in many countries. Not only associate and undergraduate education, but also studies of doctoral students who continue postgraduate education, specialty education and clinical research have been affected by the pandemic. Fast track graduation can be discussed, especially in countries where additional postgraduate measures exist: if healthcare personnel are required to pass applied proficiency exams or attend supervised study that are mandatory after graduation. As a matter of fact, obligations such as post-graduation hands-on internships, supervised work phases or a master’s degree in certain health programs provide additional education and experience.In countries where health programs graduates can take part in the provision of health services without any secondary filter or educational processes, as in our country, the subject should be handled differently. Our medical graduates start their compulsory service directly, and our graduate nurses, midwives and dentists can also participate directly in the provision of health services. The primary issue here is not to ignore the competencies and achievements of the relevant program, to correctly evaluate the authorities given by the diploma and to decide accordingly. Therefore, while evaluating the measures and decisions taken in health education during and after the COVID-19 pandemic, issues such as the type of education and post-diploma processes of the relevant country, whether there are secondary processes for competencies and achievements, and the presence of state/board exams or not should also be taken into consideration. Alternative methods need to be developed on how to make compensatory training to fulfill the gaps occurred during the epidemic, for gaining competencies of the health training... The use of artificial intelligence in training and diagnosis, digital education, virtual reality applications in surgical practices, virtual patient interviews... All in digital environment... But physical distance and digital transformation cannot be the only solution or transformation we need. Still the digital transformation that are currently underway will reveal many innovations and expansions and may enable us to adapt them in our routine life soon, while it could take almost 10 years to achieve the same level in a normal evolution.
COVID-19 Pandemic and Education
Authors: Özer Mahmut , Suna Hayri Eren
Published: July 2021

COVID-19 has been one of the biggest challenges which education systems have ever faced. Distance education solutions have become the ‘mandatory choice’ of countries to maintain educational processes in this period. Concurrently, the long-term impact of distance education on educational outputs and suggestions towards minimizing the negative effects have begun to be discussed. Predictions on the potential increase in educational inequalities after COVID-19 pandemic have become prominent in these discussions. The aim of this study is to discuss the effects of transition to distance education and potential increase in educational inequalities in detail. Steps taken by Ministry of National Education (MoNE) in pandemic and the expected educational transformations after the pandemic are also discussed. MoNE has maintained the educational services via distance education through the digital platform EBA and television broadcasting. MoNE has successfully activated the production potential and human resources particularly in vocational education institutions against the pandemic. After the pandemic, it is predicted that transitions towards digital education platforms will be accelerated, and revisions of educational processes based on the new skills demanded by labor market will be critical. The importance of remedial education is emphasized against permanent effects of inequalities in opportunity particularly in disadvantaged schools.
Opportunities and Risks in Higher Education in the Postpandemic Period
Authors: Erhan Çağrı , Gümüş Şenay
Published: July 2021

In the first half of the 2020, we all have witnessed the measures taken to stop the spread of the novel Coronavirus which causes the COVID-19 disease and slow down the pandemic in almost the whole world. One of the most significant measures which was taken to prevent gatherings in public spaces is to stop in person education altogether and move education into digital platforms. On the other hand, in the second half of the 2020, we expect to observe a controlled normalization process until a vaccine is found. Considering that until a vaccine is found, the pandemic will keep affecting people and it will take time to turn back into regular social life, higher education institutions are also expected to adopt into this controlled social life which will last a while longer and keep increasing its educational and scientific activities in this environment. Although, it is still not certain how the higher education institutions will take shape and take its place in the “new normal”, it is possible to say that there are many risks and opportunities waiting for the higher education institutions. While developments in distance and digital learning may be considered as a big opportunity for the universities, travel restrictions, economic stagnation, problems faced in distance learning and obstacles which was encountered in the internationalization process of higher education may be considered as ominously awaiting risks for the higher education institutions.
Marmara Denizinde Müsilaj Oluşumu, Muhtemel Sebepleri ve Öneriler
Authors: Aydın Mehmet Emin
Published: July 2021

Bu çalışmada Marmara Denizi’nde 2021 Haziran ayında yoğun olarak gözlenen müsilaj probleminin muhtemel oluşma sebepleri incelenmiştir. Müsilaj probleminin daha önce görüldüğü yerlerde oluşum sebepleri, çevreye, deniz ekosistemine, ekonomiye verdiği zararlar, bu tür çevre felaketlerinin oluşumunu tetikleyen bölgedeki kirlilik yükleri, Karadeniz’den gelen kirleticiler, havza dışından gelen kirleticiler, daha önceki çalışmalardan derlenmiştir. Kirleticiler içerisinde özellikle N, P gibi besi maddeleri, pestisitler, PCB’ler, PAH’lar, PBDE’ler, ağır metaller, mikroplastikler gibi mikrokirleticilerin muhtemel etkileri önemli bulunmuştur. Mikrokirleticiler besin zincirinde birikerek bazı türlerin üreme ve çoğalmalarını engelleyebilir veya yavaşlatabilir. Besin zincirinde özellikle fitoplanktonlarla beslenen deniz kabukluları ve küçük balıkların etkisinin azalması fitoplankton sayısının N, P bakımından zengin besi maddelerinin birikimi ve sıcaklığında artmasıyla kontrolsüz çoğalmalarına sebep olur. Ayrıca planktonlarla beslenen balıkların büyük miktarlarda avlanarak ortamdan çekilmesi bu durumun etkisini artıran bir faktördür.
Müsilaj Benzeri Çevre Felaketlerini Önlemede Pasif Biofilm Örnekleyiciler Kullanarak Kirlilik Yükünün Azaltılması
Authors: Bedük Fatma , Aydın Senar , Aydın Mehmet Emin , Bahadır Müfit
Published: July 2021

Kirlilik yükü artan evsel ve endüstriyel atıksu deşarjları alıcı ortam su kalitesini olumsuz yönde etkilemektedir. Marmara Denizinde görülen müsilaj sorunu, deniz suyu kalitesindeki bozulmanın ulaştığı boyutu ortaya koymaktadır. Müsilaj ve benzeri su kalitesi sorunlarının çözümü için atıksu deşarjlarının kontrol altına alınması gerekmektedir. Geleneksel numune alma yöntemleri, deşarj su kalitesinin zamansal değişimini ortaya koyamamaktadır. Biyofilm örnekleyici (ahtapot) yöntemi, deşarjların zamansal değişimini izleme fırsatı sunarak geleneksel numune alma yöntemlerinin dezavantajlarını ortadan kaldırmaktadır. Almanya’da uzun yıllardır başarılı bir şekilde kullanılan ahtapot ile biyofilm numune alma yöntemi, uygulanması kolay, ekonomik ve etkili bir yöntemdir. Yöntemin Türkiye’deki ilk uygulaması Konya’da gerçekleştirilmiş ve karar alma süreçlerine önemli katkı sağlamıştır. Bu çalışmada önerilen yöntem Marmara Denizine deşarj yapan sanayi kuruluşları ve atıksu arıtma tesislerinin çıkış suyu kalitesinin izlenmesi için etkin bir şekilde kullanılabilir. Yönetmelik sınırları üzerinde olan kaçak deşarjların izlenerek gerekli yaptırımların uygulanması Marmara Denizi su kalitesinin iyileşmesini sağlayacaktır.
Marmara Denizi’nde Müsilaj Sorunu ve Çözüm Yöntemleri
Authors: Yümün Zeki  Ünal , Kam Erol
Published: July 2021

Marmara Denizi’ne akan atıksuların taşıdığı besin maddelerinden dolayı denizde alg ve diğer fitoplanktonlar da ciddi bir çoğalma meydana gelmiştir. Alg ve diğer fitoplanktonlara bağlı olarak da Marmara Denizi’nde deniz salyası meydana gelmiş ve etkisini halen sürdürmektedir. Deniz suyunun, toplam karbon, inorganik karbon, toplam organik karbon ve toplam azot değerleri analiz edilmiştir. Deniz salyasının da toplam karbon, inorganik karbon, toplam organik karbon ve toplam azot değerleri saptanmıştır. Müsilajın pH değeri 6,70-6,94 arasında, deniz suyunun pH değeri ise 7,97-8,15 arasındadır. Müsilajın asidik, deniz suyunun ise bazik olduğu görülmektedir. Yapılan azot+fosfor deneyinde deniz suyunun pH değeri 7,13-7,25’e kadar düştüğü, müsilajda ise 6,4’e düşerek ortamın asitleştiği görülmüştür. Deniz suyunun asitliğin artışıyla birlikte elektrik iletkenliği de artmıştır. Deniz salyasının çözünmüş oksijen miktarı ölçülemeyecek kadar küçük olup, %25 tatlı su katılması durumunda oksijen değeri 1,21- 1,22 ppm’e kadar yükselmektedir. Deniz ekosisteminin korunması için denize arıtılmamış sular atılmamalı, bunun aksine Marmara Denizi’ne tatlı su veya oksijeni yüksek deniz sularının katılması, deniz ekosisteminin korunmasına katkı yapacaktır.
Marmara Denizi’nin Geçirdiği Biyojeokimyasal Değişimler Bağlamında 2021 Müsilaj Patlaması, Güncel Baskılar ve Çözüm Önerileri
Authors: Yüce Mustafal , Özkan Korhan , Fach Bettina , Örek Hasan , Mantıkçı Mustafa , Tezcan Devrim , Akçay İsmail , Özhan Koray , Arkın Sinan , Tuğrul Süleyman , Salihoğlu Barış
Published: July 2021

ODTÜ Deniz Bilimleri Enstitüsü’nün son 40 yılda R/V Bilim-2 gemisi ile topladığı veriler Marmara Denizi’nin organik madde ve besin tuzları açısından giderek zenginleştiği ve oksijen azlığı (hipoksia) çekmeye başladığını göstermiştir. Marmara Denizi’nin iki tabakalı sistemini oluşturan üst 25-30 metredeki Karadeniz ve altındaki Akdeniz kaynaklı sular, oşinografide haloklin adı verilen keskin bir tuzluluk geçişi ile ayrılmıştır. Haloklin altı sularda özellikle Doğu Marmara›da ciddi hipoksia görülmekte ve artan azot ve fosfor tuzu girdileri ile Marmara Denizi aşırı üretkenlik- ötrofikasyon baskısı çekmektedir. 2021 yılındaki müsilaj patlamasının da temel nedeni Marmara Denizi’nin bu yeni biyojeokimyasal durumu sayılmalıdır. ODTÜ Deniz Bilimleri Enstitüsü koordinasyonunda T.C. Çevre ve Şehircilik Bakanlığı desteği ile yürütülen MARMOD projesi (2017-devam) ile Marmara besin bütçesinde en büyük payın sıra ile yayılı yükler, noktasal deşarjlar ve Karadeniz suyu olduğu sonucuna varılmıştır. MARMOD modelleme sonuçlarına göre karasal girdilerde en az yüzde 40’lık bir azot-fosfor yükü azalımı ile sistem hipoksia eşiğini en az 5-6 yılda aşabilir. Bir başka deyişle, son derece kırılgan bir ekosistem durumuna gelen Marmara Denizi için geriye dönüş mümkündür. Bu nedenle beklenmeden tüm kaynaklarda en güçlü efor ile yük azaltım önlemleri alınmalı ve denize ek besin yükü getirecek her türlü yeni uygulamadan kaçınılmalıdır.
Perancangan Sistem Informasi Pelayanan Pengobatan Pasien Umum Dan Bpjs Menggunakan Visual Basic Pada Klinik Batara Di Jalan Panglima Denai Kota Medan Provinsi Sumatera Utara Tahun 2019
Authors: Sari Diah Indah , Jannah Raudhatul , Caniago Ari Usman
Published: July 2021

sistem informasi sangat diperlukan di klinik agar dapat membantu dalam melakukan tugas-tugas administrasi klinik guna meningkatkan mutu pelayanan klinik yang melayani masyarakat di bidang kesehatan. Registrasi pasien di klinik merupakan salah satu komponen dalam sistem informasi yang sangat diperlukan karena pelayanan yang diberikan di klinik harus optimal dalam arti cepat dan tepat. Saat ini, sistem registrasi pasien yang dilakukan di klinik Batara masih dilakukan secara manual. Sehingga memiliki banyak kelemahan yang akan menurunkan mutu pelayanan kesehatan. Penelitian ini bertujuan untuk merancang sistem informasi registrasi pasien di klinik Batara agar mempermudah pendaftaran pasien yang sebelumnya dilakukan secara manual.Metode pengembangan sistem registrasi pasien ini dibuat dengan menggunakan metode siklus hidup pengembangan sistem atau System Development Life Cycle (SDLC). dan dirancang menggunakan perangkat lunak Microsoft Visual Studio. Metode tersebut meliputi beberapa tahapan proses yaitu tahap perencanaan sistem, tahap analisis sistem, tahap perancangan sistem, tahap penerapan sistem, tahap evaluasi sistem, tahap penggunaan dan pemeliharaan sistem. Hasil dari pengembangan sistem registrasi ini adalah sebuah perangkat lunak (software) yang dikembangkan menggunakan perancangan input, perancangan database dan perancangan output, yang berguna membantu petugas klinik dalam pencatatan data pasien. Berdasarkan hasil penelitian, diharapkan kepada klik Batara agar mempersiapkan sarana prasarana untuk mendukung berjalannya sistem ini, serta menerapkan perangkat lunak ini di bagian registrasi pasien agar mempermudah proses pendaftaran dan pembuatan laporan kunjungan pasien sehingga m enghasilkan informasi yang akurat
Analisis Kemampuan Akademik Mahasiswa Berdasarkan Latar Belakang Keluarga, Tempat Tinggal, Pertemanan, Sikap Belajar, Konsep Diri, Iklim Kampus, Dan Tenaga Pengajar Dengan Jaringan Syaraf Tiruan Backpropagation Armansyah*, Guntur
Authors: Armansyah Armasyah , Syahputra Guntur , Perangin-angin Moch Iswan
Published: July 2021

Dalam hal akademis, Indeks Prestasi Kumulatif (IPK) merupakan tolok ukur prestasi pelajar termasuk mahasiswa. IPK itu sendiri adalah produk hasil dari proses belajar yang diperoleh dari berbagai bentuk evaluasi. Tingginya perolehan IPK mahasiswa kemudian menganggap bahwa mahasiswa dipandang memiliki kemampuan yang baik pula dalam setiap perkuliahan. Namun ternyata anggapan tersebut tidak sepenuhnya benar. Penelitian ini bertujuan untuk memprediksi tingkat kemampuan mahasiswa dalam perkuliahan, terutama untuk matakuliah program studi, khususnya pemrograman. Parameter yang disoroti pada penelitian ini adalah latar belakang keluarga, tempat tinggal, lingkungan pertemanan, sikap belajar, konsep diri, iklim kampus dan tenaga dosen. Kami berpendapat bahwa ketujuh komponen tersebut jika relevan dengan diri mahasiswa dapat memengaruhi tingkat kemampuan mahasiswa. Jaringan Syaraf Tiruan Backpropagation digunakan untuk melatih dan menguji data dari hasil kuesioner berdasarkan ketujuh komponen diatas. Dari beberapa percobaan, keluaran dan target sangat mendekati dengan tingkat akurasi mencapai 99,50% dengan nilai MSE paling kecil 10-7 atau 0,0000001.
Implementasi Teknik Pulse Width Modulation Untuk Kendali Motor Pada Alat Pemotong Bawang Berbasis Mikrokontroler
Authors: Prayudha Jaka , Azanuddin Azanuddin , Sobirin Sobirin
Published: July 2021

Dalam melakukan pengirisan bawang selama ini masih menggunakan cara manual yaitu memotongnya dengan pisau atau pengiris. Disamping berbahaya, cara ini juga memakan waktu dan selalu menyakitkan mata. Dari proses pengerisan bawang diatas sangatlah jelas bahwa jumlah irisan yang dihasilkan terbatas. Untuk keperluan rumah tangga mungkin cara ini masih dapat diterima, akan tetapi untuk skala produksi misalnya industri atau pun restoran, cara ini kurang efektif dan mahal.Maka dengan ini dirancang suatu alat pengiris bawang semi otomatis dengan menggunakan mesin yang dirancang berbasiskan mikrokontroler aduino uno. Metode yang digunakan adalah teknik Pulse Witdh Modulation (PWM). Sistem penggerak mekanis adalah sebuah motor DC. Sedangkan sensor dalam rancangan ini adalah ultrasonik. Mesin bekerja dengan menggerakkan motor yang telah dipasang pengiris. Sensor akan mendeteksi keberadaan bawang dalam wadah sehingga mesin akan berhenti saat bawang telah habisMaka dengan dibuatnya suatu alat pengiris bawang yang menggunakan teknik Pulse Witdh Modulation (PWM) ini dapat memudahkan manusia untuk mengiris bawang dengan lebih mudah dan cepat, dan alat ini lebih praktis dan tidak berbahaya dan tidak membuat mata menjadi perih. Dan alat ini dapat digunakan untuk skala besar.
Aplikasi Pencatatan Kehadiran Murid Menggunakan Komputer Dengan RFID Card Dan SMS Gateway
Authors: Wijaya Victor , Wijaya Tedy , Priscilla Jennifer , Laia Yonata
Published: July 2021

Pencatatan dan pengolahan data absensi dengan menggunakan kartu absensi mengakibatkan data yang diperoleh menjadi kurang akurat. Untuk meningkatkan keakuratan data, diperlukan pembangunan aplikasi absensi yang terkomputerisasi. RFID merupakan salah satu komponen yang sering digunakan sebagai alat identifikasi yang handal dan akurat selama bertahun-tahun. SMS Gateway merupakan suatu sistem yang dapat mengirimkan pesan SMS pada nomor telepon.Aplikasi absensi ini dirancang dengan menggunakan bahasa pemrograman Visual Basic 2010 dan menggunakan database MySQL. Program ini memungkinkan user untuk input data, edit data, hapus data, pencarian data, penyaringan data dan pencetakan data ke media kertas. Data yang dimasukkan berupa data murid dan data absensi. Sedangkan output yang dihasilkan sistem informasi ini berupa laporan data absensi. Aplikasi absensi ini dapat menjadi salah satu solusi yang dapat digunakan untuk mempermudah personalia dalam mengolah dan membuat laporan data absensi menjadi lebih mudah, cepat dan efisien
E-KPI Menggunakan Metode MOORA (Multi Objective Optimization On The Basis Of Ratio Analysis) dalam menentukan Engineer yang memperoleh bonus pada CV. Arisanita
Authors: Boy Ahmad Fitri , Amrullah Amrullah , Nasyuha Asyahri Hadi , Syahputra Trinanda
Published: July 2021

Dalam meningkatkan kesejahteraan karyawan, maka CV. Arisanita akan memberikan bonus pada setiap engineer yang memenuhi kriteria yang ditetapkan oleh perusahaan tersebut. Mengingat banyaknya karyawan yang ada di perusahaan maka perlu di lakukannya penentuan karyawan yang layak menerima bonus.Dalam mendukung perhitungan dari setiap kriteria yang telah ditentukan maka dibutuhkan suatu metode. Pada saat ini digunakanlah metode Metode Multi-Objective Optimization by Ratio Analysis dalam perhitungan dari kriteria tersebut. MOORA adalah suatu metode pengambilan keputusan yang paling sesuai dengan menggunakan cara pembobotan.Hasil penelitian ini adalah: Pertama Berdasarkan Analisa pengaruh sistem pendukung keputusan terkait masalah yang diangkat ditandai dengan semakin cepat proses penentuan melalui hasil yang didapat, Kedua Berdasarkan Perancangan sistem pendukung keputusan menggunalan metode MOORA dalam penentuan engineer yang memperoleh bonus, Ketiga telah dilakukannya implementasi sistem pendukung keputusan berbasis desktop maka sistem yang dirancang dapat digunakan dalam penyelesaian masalah pemilihan engineer
Penerapan Data Mining Dalam Menentukan Pola Ketersediaan Stok Barang Berdasarkan Permintaan Konsumen Di Chykes Minimarket Menggunakan Algoritma Apriori
Authors: Ginting Idul Fitri Polorida , Saripurna Darjat , Fitriani El
Published: July 2021

Persediaan Merupakan suatu yang penting bagi perusahaan karena sebagian besar aktiva perusahaan tertanam pada persediaan. Dengan adanya persediaan perusahaan dapat menjaga kelangsungan hidupnya masalah yang sering dialami dalam akuntansi.Dari hasil penelitian yang dilakukan pada chykes minimarket  dalampengecekan ketersedian stok barang  pada dasarnya masih bersifat manual, tidak adanya sistem yang dapat memberikan serta memudahkan kepada perusahaan atau bagian gudang.Dengan masalah tersebut diatas maka dibutuhkan sebuah sistem yang mampu mempemudah serta memberikan informasi kepada perusahaan atau bagian gudang dengan cepat.Hasil dari penelitian ini mendapatkan suatu keluaran berupa hasil pola ketersediaan stok barang atau persediaa barang pada chykes minimarket dengan metode algoritma apriori.
Page de garde
Authors: Al Et.
Published: July 2021

Page de garde Vol 16 numero 2
Discussing the Relationships between Consumer Experiential Value, Celebrity Endorsement and Brand Resonance – Case Study of the STAYREAL Brand
Authors: Wang Yun , Lin Yu-Tzu
Published: July 2021

Based on the perspective of concert experience marketing, this research explores whether consumers resonate with the brand STAYREAL through celebrity endorsements while using the P-O-X theory as the research’s structure. Research subjects are audiences who have participated in the Mayday concerts. Mall-intercepts method with intentional sampling is used and questionnaires were distributed at the “Super Slippa– part 9” and “The Great Nobody” of 831 rock band in 2018 at the Taipei Arena. 422 valid questionnaires were returned from the 469 distributed. Data were analyzed using the statistical software SPSS19.0 and it was found that: 1. Experience value has a significant positive impact on celebrity endorsements; 2. Experience value has a significant positive impact on brand resonance. 3. Celebrity endorsements have a significant positive impact on brand resonance; 4. Celebrity endorsements have a partial intermediary effect between experience value and brand resonance, which proves that P-O-X is in a balanced state. In order to reach a stage of consumers’ resonance with the brand, future research can examine the utility factors such as brand attributes in price, design, fabric, comfort, color, etc. at the same time.
Weed Occurrence in a Young Apple Orchard Mulched With Two Different Organic Materials
Authors: Licznar-Małańczuk Maria , Slobodianyk Liudmyla
Published: July 2021

In this study, conducted at the Research Station of the Wrocław University of Environmental and Life Sciences, Poland, we sought to determine the communities of weed species and their temporal occurrence in a young apple orchard mulched with spent mushroom compost or
Miscanthus
straw applied to tree rows. A herbicide fallow treatment was used as a control. During the first year of application, both organic mulches protected against the germination of weed seeds stored within the soil. In subsequent years, however, annual weeds occurred in the mulched tree rows, the most aggressive of which was
Chenopodium album
L. Annual increases in population densities were noted over the 4 subsequent years of research, particularly in the rows receiving spent mushroom compost. Perennial species in the family Poaceae and genus
Malva
were present in soil receiving both organic mulches.
Trifolium repens
L. was the perennial weed most often noted in the
Miscanthus
mulch, whereas
Taraxacum officinale
Web. was more characteristic of the spent mushroom compost. Commencing from the spring of the third year following apple tree planting, weed infestation associated with the spent mushroom compost was similar to that observed in the herbicide fallow, thus necessitating three annual applications of herbicide to further maintain the orchard. The insufficient weed suppression obtained with this mulch precludes its recommendation as an effective weed management system. Although
Miscanthus
straw provided extended tree row protection from weed infestation, herbicide intervention was also required. Notably, however, despite the fact that
Miscanthus
straw provided conditions more favorable to tree growth, apple tree yields and fruit quality tended to be similar under the three investigated orchard soil management systems.
Early Dermoscopic Signs Leading to Primary Systemic Amyloidosis’ Diagnosis: A Case Report
Authors: Hassanandani Trashita , Singh Bhabani S.T.P. , Kar Bikash Ranjan
Published: July 2021

Amyloidosis is primarily extracellular deposition of insoluble polymeric protein fibrils in tissues and organs. About 25 percent of patients with primary systemic amyloidosis have associated skin lesions in the form of papules, plaques or nodules. Dermoscopy of these skin lesions reveals characteristic glomerular vessels on a red to pink background. Here we present unique dermoscopic features of cutaneous lesions in a case of primary systemic amyloidosis.
Sodium Hypochlorite 0.005% Versus Placebo in the Treatment of Mild to Moderate Acne: A Double-Blind Randomized Controlled Trial
Authors: Dorostkar Azadeh , Ghahartars Mehdi , Namazi Mohammad Reza , Todarbary Nafiseh , Hadibarhaghtalab Maryam , Rezaee Maryam
Published: July 2021

Background: Acne vulgaris is a common inflammatory disease of the pilosebaceous follicle thataffects many teenagers and young people. There is an obvious need for topical treatments with goodtolerability and efficacy for the management of acne lesions.

Objective: This study determined the therapeutic efficacy of topical sodium hypochlorite solution(0.005%) in the treatment of mild to moderate acne lesions.

Methods: This placebo-controlled randomized controlled trial compared 0.005% sodium hypochloriteto placebo administered topically on each side of the patients’ faces 3 times a day for 1 month. Thenumbers of papules and pustules were recorded at baseline, 1, 2 and 4 weeks after initiation.

Results: The total number of papules and pustules decreased after topical application of sodiumhypochlorite 0.005% for 1 month.

Conclusions: Topical sodium hypochlorite solution (0.005%) can be effective in the treatment of mildto moderate acne, and its clinical efficacy was evaluated between the male and female groups andbetween the hormonal and non-hormonal ones.

Trial registration: Our study was registered in the Iranian Registry of Clinical Trials (IRCT) with thecode number IRCT20200701047976N1.
Calcipotriol/Betamethasone Dipropionate Aerosol Foam for Plaque Psoriasis: A Prospective, Observational, Non-Interventional, Single-Center Study of Patient Adherence and Satisfaction in Daily Use
Authors: Navarro-Triviño Francisco J , Lozano-Lozano Mario , Ruiz-Villaverde Ricardo
Published: July 2021

Background: Psoriasis is a chronic inflammatory disease that has a negative impact on patients' quality of life. Patients with mild–moderate psoriasis can be treated with topical medications, such as the combination drug calcipotriol/betamethasone dipropionate (Cal/BD).  

Objectives: This study investigated the adherence of psoriasis patients to therapy with Cal/BD aerosol foam, as well as their satisfaction with the treatment’s efficacy, safety, and effect on their quality of life.

Methods: Patients with mild–moderate plaque psoriasis were eligible to participate in this open-label, non-placebo controlled, prospective single-center study. Adherence to treatment was assessed using the Morisky-Green scale 4 and 12 weeks after the start of treatment. Satisfaction with the treatment was assessed using the abbreviated Treatment Satisfaction Questionnaire for Medication (TSQM-9). The severity of psoriasis was assessed on the mIGA and PGA scales, and the impact on quality of life was assessed using the PDI and DLQI scales.

Results: A total of 65 patients entered the study. Adherence to treatment was good, with 73.8% of patients showing high adherence at 12 weeks. Satisfaction was also good, with 46 patients (70.8%) being completely satisfied.

Conclusions: Over a 4-week period, patients treated with Cal/BD aerosol foam had significant improvement in disease severity that was directly related to treatment adherence.
Risk of Birth Defects From Vitamin A “Acne Supplements” Sold Online
Authors: Zamil Dina , Burns Emily , Perez-Sanchez Ariadna , Parke Milbrey , Katta Rajani
Published: July 2021

Background: Dietary supplements are popular among US consumers and claim to address a variety of conditions, including acne. Acne supplements containing vitamin A are of particular interest, due to the potentially teratogenic effects of vitamin A doses over 10,000 IU.

Objective: This study examined dosage, pregnancy risks, and labeling of vitamin A-containing acne supplements available online.

Methods: An Internet search of acne supplements sold online was conducted between March and May 2020. Supplement labels and websites were analyzed for vitamin A content and pregnancy warnings, and then divided into categories based on dosage and teratogenic risk.

Results: A total of 49 acne supplements was found, and of these 26 (53%) contain vitamin A. Three supplements are likely teratogenic, 4 contain vitamin A doses exceeding the daily level of intake that meets the nutritional needs of most people, and  15 have an unknown teratogenic risk. Among the 6 supplements with over 10,000 IU vitamin A, 2 have no pregnancy warning at all, including the supplement with the highest vitamin A dose found in this study.

Conclusions: Dietary supplements are not subject to the same stringent regulations as drugs, and as such, consumers may be unaware of pregnancy risks. Furthermore, FDA requirements on labeling of vitamin A supplements may lead to consumer confusion regarding dosage. As such, we encourage stricter labeling requirements for vitamin A-containing supplements, including pregnancy warnings for high-dose supplements and clearer dosage labeling.
The Effectiveness and Tolerability of Preformed Growth Factors Vehiculated Through Iontophoresis on Patients with Androgenetic Alopecia and Telogen Effluvium: A Clinical Study
Authors: Alessandrini Aurora Maria , Bruni Francesca , Piraccini Bianca Maria , Starace Michela
Published: July 2021

Background: Androgenetic alopecia is characterized by a progressive miniaturization of hair follicles in a pattern distribution in genetically predisposed individuals. The efficacy of conventional therapies is variable, therefore there is a need for adjuvant and newer treatment modalities to provide faster and better outcomes.

Objectives: Evaluation of the efficacy and tolerability of a combined therapy: preformed growth factors vehiculated through iontophoresis in patients with androgenetic alopecia and associated telogen effluvium, to obtain faster hair regrowth.

Materials and Methods: Treatment was performed between June 2018 and June 2019 on 60 patients with androgenetic alopecia and associated telogen effluvium. Each patient underwent 4 sessions in total, each session was performed every 3 weeks. Global photography and trichoscopy were collected at every session of therapy. All patients filed out a self-assessment questionnaire.

Results: Results were very promising, with improvement of hair density and thickening of the hair shaft diameter in most of patients seen with both global photography and trichoscopy. All patients were satisfied of the clinical result and reported a complete reduction in hair loss. No serious adverse side effects were reported.

Conclusions: The use of growth factors associated with iontophoresis technique is a useful treatment for treating and preventing androgenetic alopecia. In addition, in case of associated telogen effluvium, this technique allows for an early stop of hair shedding, especially when cosmetic procedures do not provide satisfactory results in patients.
Clinicopathologic Characteristics and Outcome Descriptors of Metaplastic Breast Carcinoma
Authors: Abada Evi , Daaboul Fayez , Ebare Kingsley , Jang Hyejeong , Fehmi Ziad , Kim Seongho , Ali-Fehmi Rouba , Bandyopadhyay Sudeshna
Published: July 2021

Context.—

Metaplastic breast carcinoma is an aggressive form of breast cancer that accounts for 0.5% to 3% of all breast cancers.

Objective.—

To study the clinicopathologic characteristics and outcomes of this rare disease.

Design.—

Retrospective study of patients with a diagnosis of metaplastic breast carcinoma between 2000 and 2019. Hematoxylin-eosin–stained slides were reviewed and additional clinical data were obtained from electronic medical records. Univariable and multivariable Cox proportional hazard regression analyses were used to determine associations between overall survival and several clinicopathologic variables.

Results.—

Of the 125 patients with metaplastic breast carcinoma identified, only patients with high-grade disease (N = 115) were included in the data analysis. A total of 38 participants (33%) were white, 66 (57%) were African American, and 11 (10%) belonged to other ethnicities. The median age at diagnosis was 57 years. The median tumor size was 3 cm. Heterologous histology was seen in 30% of cases. Multivariable analyses showed that patients with a larger tumor size had worse overall survival (hazard ratio [HR], 1.25; 95% CI, 1.10–1.44; P < .001). Distant metastatic disease was also associated with worse overall survival on multivariable analysis (HR, 10.27; 95% CI, 2.03–55.54; P = .005). In addition to treatment with either partial or complete mastectomies, 84 patients (73%) received chemotherapy. Multivariable analyses showed that chemotherapy had no effect on overall survival (HR, 0.53; 95% CI, 0.09–6.05; P = .55).

Conclusions.—

A larger tumor size and distant metastatic disease are associated with worse overall survival in patients with metaplastic breast carcinoma. Additional studies are needed to further characterize our findings.
El El significado del trabajo en tres mujeres de Guadalajara, México: género, clase y generación
Authors: Palomar Cristina
Published: July 2021

El tema de esta investigación se relaciona, por un lado, con el ámbito de los estudios acerca del significado actual del trabajo, y por el otro, con el del estudio del vínculo de dicho significado con la construcción de las identidades. En la confluencia de ambos campos de trabajo, se hizo una investigación que buscó entender la relación entre el sentido del trabajo y la construcción de la identidad de género, a través del análisis de las narrativas de trayectorias vitales de tres mujeres de Guadalajara, México, de clase media y de tres generaciones sucesivas de una misma familia. Se presentan en este trabajo algunos resultados de dicho análisis.
Sculpture and New Technologies in Scientific Educational Outreach: 3D Foraminiferal Models as a Referent of Ocean Acidification and Climate Change
Authors: G. Peco Víctor , Garzón-Arenas Nerea , Espinel José Carlos , Herrero Concha
Published: July 2021

The Foraminifera Project is a collaboration between researchers of the Faculty of Fine Arts and the Faculty of Geological Sciences at the Complutense University (UCM, Madrid, Spain). The work, based on scientific dissemination through art, is framed in the theme “Climate change and Ocean Acidification'' as part of the course “Art, Science and Nature” of the Master's Degree in Research in Art and Creation (Faculty of Fine Arts, UCM). The team used recent sediment samples from Indian Ocean and Red Sea that contained healthy and unhealthy foraminifera specimens to create 3D specimen models. These models were made using traditional sculpture techniques, photogrammetry, and 3D printing to show different states of foraminifera dissolution and corrosion from ocean acidification. The end result of this project resulted in nine interactive pieces which were part of the exhibition “Drift & Migrate'' open to the public during the month of November 2019 in the exhibition hall of the Faculty of Fine Arts (UCM). The 3D models of foraminifera were displayed with educational graphics and blind-accesible explanatory signage (Braille) to share the scientific facts of foraminifera and their role in the ocean ecosystem. The main objective of the collaboration is to raise awareness of anthropogenic effects on foraminifera and the marine ecosystems in general and to expand research opportunities between the arts and sciences at the university.
Estrategias del cine volumétrico para generar empatía en la audiencia. El caso de Queerskins: Ark
Authors: Martínez-Cano Francisco-Julián , Roselló-Tormo Emilio , Roselló-Tormo Emilio
Published: July 2021

El registro volumétrico ofrece la posibilidad de trabajar con grabaciones de actores reales en producciones cinematográficas interactivas de realidad virtual. Queerskins: Ark (Szilak y Tsiboulski, 2020) es una de las primeras creaciones narrativas que aplican y exploran esta técnica, capaz de potenciar las respuestas empáticas de la audiencia. El presente trabajo parte del análisis de esta obra, con el objetivo de identificar los procedimientos de creación empleados en su construcción. Este estudio emplea una metodología cualitativa que se compone de tres fases. Una primera de revisión bibliográfica, posteriormente se profundiza en el proceso de creación de Queerskins: Ark a través de una serie de entrevistas semiestructuradas a los autores. Finalmente se analiza el metraje virtual aplicando un modelo propio diseñado en tres bloques. Los proyectos de investigación, llevados a cabo para comprobar el impacto de la narrativa audiovisual de RV en el espectador, siempre han optado por las estrategias de toma de perspectiva. La obra objeto de estudio, por el contrario, experimenta con la aplicación de recursos expresivos y artísticos con el mismo fin. Los resultados expuestos demuestran la existencia de métodos alternativos para generar respuestas empáticas en la audiencia.
Total connected domination game
Authors: Bujtás Csilla , Henning Michael A. , Iršič Vesna , Klavžar Sandi
Published: July 2021

The (total) connected domination game on a graph \(G\) is played by two players, Dominator and Staller, according to the standard (total) domination game with the additional requirement that at each stage of the game the selected vertices induce a connected subgraph of \(G\). If Dominator starts the game and both players play optimally, then the number of vertices selected during the game is the (total) connected game domination number (\(\gamma_{\rm tcg}(G)\)) \(\gamma_{\rm cg}(G)\) of \(G\). We show that \(\gamma_{\rm tcg}(G) \in \{\gamma_{\rm cg}(G),\gamma_{\rm cg}(G) + 1,\gamma_{\rm cg}(G) + 2\}\), and consequently define \(G\) as Class \(i\) if \(\gamma_{\rm tcg}(G) = \gamma_{\rm cg} + i\) for \(i \in \{0,1,2\}\). A large family of Class \(0\) graphs is constructed which contains all connected Cartesian product graphs and connected direct product graphs with minumum degree at least \(2\). We show that no tree is Class \(2\) and characterize Class \(1\) trees. We provide an infinite family of Class \(2\) bipartite graphs.
GrimoireLab: A toolset for software development analytics
Authors: Dueñas Santiago , Cosentino Valerio , Gonzalez-Barahona Jesus M. , del Castillo San Felix Alvaro , Izquierdo-Cortazar Daniel , Cañas-Díaz Luis , Pérez García-Plaza Alberto
Published: July 2021

Background

After many years of research on software repositories, the knowledge for building mature, reusable tools that perform data retrieval, storage and basic analytics is readily available. However, there is still room to improvement in the area of reusable tools implementing this knowledge.

Goal

To produce a reusable toolset supporting the most common tasks when retrieving, curating and visualizing data from software repositories, allowing for the easy reproduction of data sets ready for more complex analytics, and sparing the researcher or the analyst of most of the tasks that can be automated.

Method

Use our experience in building tools in this domain to identify a collection of scenarios where a reusable toolset would be convenient, and the main components of such a toolset. Then build those components, and refine them incrementally using the feedback from their use in both commercial, community-based, and academic environments.

Results

GrimoireLab, an efficient toolset composed of five main components, supporting about 30 different kinds of data sources related to software development. It has been tested in many environments, for performing different kinds of studies, and providing different kinds of services. It features a common API for accessing the retrieved data, facilities for relating items from different data sources, semi-structured storage for easing later analysis and reproduction, and basic facilities for visualization, preliminary analysis and drill-down in the data. It is also modular, making it easy to support new kinds of data sources and analysis.

Conclusions

We present a mature toolset, widely tested in the field, that can help to improve the situation in the area of reusable tools for mining software repositories. We show some scenarios where it has already been used. We expect it will help to reduce the effort for doing studies or providing services in this area, leading to advances in reproducibility and comparison of results.
A Content Review of News about Coronavirus Disease (COVID-19) at Media Prior to Emergence in Pakistan by the Year 2020
Authors: Ali Muhammad Ghafoor , Husain Saima Narjees , Shah Syed Imran Ahmad
Published: July 2021

The study has been carried as a review of news about coronavirus disease (COVID-19) published in main stream newspaper (Daily Jang) prior to emergence in Pakistan. The front page of newspaper Daily Jang-Pakistan was selected for evaluation of study. The duration of study was from 31st December 2019 to 27th February 2020.The data has been qualitatively analyzed about text analysis, interpretative analysis, discourse analysis, rhetorical analysis, narrative analysis, and semiotic analysis whereas quantitatively analyzed for increasing number of patients, death and global bifurcation of affected cases. The first case of COVID-19 apparently reported on 31st December 2019 in China and got place at front page of newspaper on 24th January 2020 with 571 affected persons and 17 deaths.By 28th January 2020 USA, Canada, Australia, France, Japan, Thailand, Taiwan, Vietnam, Singapore, Malaysia and Nepal were affected from new viral disease and till 5th of February 2020 more than two dozen countries confirmed about existence of new disease. China has taken immediate health interventions. Subsequently strategies were made in the world including Pakistan. WHO made global strategies to control new viral disease. Although most countries shifted their citizen from China however Pakistan did not removed their citizen from affected country. In the light of Hadith, Muslim Scholars advised that citizens of Pakistan should not be shifted outside China till control of disease. The scientist started to investigate new disease. The herbal medicine also used in public. Campaign on media started about awareness of new disease. The business activity found to be reduced due to disease. Necessary preventive arrangements were made by the aviation department. Pakistan also banned on import of animal and birds. The burial ceremonies of deceased due to COVID-19 were also limited for participation. Many operations like Haj, Umrah and Olympic 2020 expected to be affected due to new viral disease. However a common marriage found to be reported in South Korea. Dr.Ventiang died on 8th February 2020 who initially suspected and diagnosed for existence and origin of new disease. On 26th   February 2020 a news  on front page indicating to inner page that “many countries affected by corona virus disease and afterward on 27th February 2020 there was a main headline news on the front page that “Corona reached Pakistan.”
Role and Usefulness of C-reactive Protein in Women with Polycystic Ovarian Syndrome
Authors: Adhikari Indra Prasad , Nigoskar Shreya , Singh Amresh Kumar , Mishra Arun
Published: July 2021

Background: Polycystic ovary syndrome (PCOS) is a complex medical condition characterized by elevated androgen levels, menstrual irregularities, and small cysts on one or both ovaries. The prevalence of PCOS is 6 to 10% in women. C-reactive protein (CRP) is an acute-phase protein produced by the hepatic cells and it’s levels increased in inflammation that increases interleukin-6 by macrophages and T cells.

Aims and Objective: A correlative study of role and usefulness of CRP in women with PCOS and its correlation with different biochemical parameters.

Materials and Methods: This was hospital based case-control study carried out among PCOS was conducted in the Department of Obstetrics & Gynaecology, Index Medical College Hospital, Indore. This study was conducted from 1st January 2018 to 31st December 2019. A total of 260 subjects with age group between 15 to 45 years were divided into two group; cases (130) and controls (130).

Results: Among a total of 260 cases, based on clinical and different biochemical parameters, 130 were diagnosis with PCOS and 130 were apparently healthy women. The mean ±SD of various parameters among PCOS cases were; body mass index (BMI) 32.97±8.466, P (<0.001) total cholesterol (TC) 188.42±31.126, P (<0.001), triglyceride (TG) 134.43±50.01, P (<0.001), high density lipoprotein (HDL) 36.29±9.55 TC/HDL ratio, 5.54±1.865 serum CRP, 3.41±0.94 versus BMI 22.87±2.470, P (<0.001), TC155.42±26.333, TG 110.00±42.19, HDL 41.22±10.912, TC/HDL ratio 4.08±1.39, serum CRP 2.25±0.83 P (<0.001) in healthy control.

Conclusion: In this study, the role of inflammation and different biochemical markers were studied among PCOS. It was found that a majority of PCOS patients were obese, having insulin resistance. The levels of CRP as a marker of chronic low grade inflammation were higher in newly diagnosed PCOS as compared to the controls. The CRP values correlated well (statistically significant) with increased in BMI and age.
Aso-ebi Custom among the Yoruba People of Southwest Nigeria: An Assessment of Trend, Challenges and Prospects
Authors: Badeji Susan Olubukola
Published: July 2021

The study investigated the trend, challenges and prospects of Aso-Ebi practice among the Yoruba people of Southwest Nigeria. The major objective of the study was to compare the benefits of the phenomenon with the challenges associated with it. This is to reach a cogent premise for upholding or discouraging the practice. The methodology followed a survey research design that involved generating data from individuals who patronize Aso-Ebi in Osun and Oyo States. Primary data sources came from a well-designed questionnaire which was administered to 270 respondents. The result findings revealed that: (i) Distress arising from the financial burden emanating from incessant purchase of Aso-Ebi fabrics (ii) Distress caused by unhealthy flamboyant competition among Aso-Ebi patrons, and (iii) Distress caused by compromising personal taste and choice for chosen Aso-Ebi fabrics are all significant challenges allied with the phenomenon. On the other hand, (i) Distress caused by the suspension of the use of personal clothes (ii) Distress caused by stocking loads of Aso- Ebi fabrics in personal wardrobes are found not to be significant. The study also found that the benefits associated with the practice outweigh the challenges therein. Consequently, it was recommended in the study that: (i) the practice of Aso-Ebi should be upheld and encouraged (ii) individuals, organizations and the Nigerian government at all levels should leverage on its potentials as a panacea for capacity building and economic growth (iii) it should be harnessed as an instrument for fostering social cohesion in Nigeria.
Comparative Evaluation of Phytochemical Constituents by GC-MS and Antitubercular & Antimicrobial Potential of Ceiba pentandra and Parmotrema perlatum against Resistant Strains
Authors: Devi K. Varalakshmi , Bhargav E. , Swaruparani G. , Jyothi M. Vijaya
Published: July 2021

Ceiba pentandra and Parmotrema perlatum lichen are two illustrious spices. Apart from their benefit as aromas, These are known for various therapeutic activities. Both are well known as appetizers. Decoctions of theses powders are used to relieve cough, anorexia and helminthiasis etc. Though several studies on antimicrobial activities of these two plants are available, studies on resistant microorganisms and anti tubercular activity are very limited. Hence, the author made an attempt to identify the phytochemical constituents present in methanolic and n-hexane extracts of Ceiba pentandra and Parmotrema perlatum using phytochemical tests and GC-MS method          then to evaluate antibacterial activity against 5 resistant microorganisms by microtitre broth dilution method using ciprofloxacillin & streptomycin as reference standards. Methanolic extracts of Parmotrema perlatum and Ceiba pentandra had shown a considerable antibacterial activity than n-hexane extracts and exhibited 90% growth inhibition against H37Rv resistant strain of mycobacterium at 80 & 320 micrograms/ml respectively. N-hexane extracts of both species were found to be poorly effective against H37 Rv.