bluuebunny/crossref_metadata_2025 huggingface dataset:
Vaccination with vector type vaccines – is it worth the risk?
Authors: Ale Ben , Slater David , Hartford Des
Published: June 2021

COVID-19 has the potential to re-frame the whole debate about individual and societal risk, risk balancing, benefit-cost analysis, individual rights, societal responsibilities of individuals and responsibilities of Governments within the overall context that there are limits to what can be achieved in particular instances, and in totality across society. There has been considerable discussion and debate globally about the real and perceived risks of having a vaccination against COVID-19. This might be interpreted as having contributed to the uncertainty in the vaccine debate and contributed to doubt and even erosion of trust in some of the population. Some of this has been due to an understandable demand for immediate answers, before the necessary and detailed data were available and verified. The recent publication of unexpected negative side effects from the Astra Zeneca version of the vector-type vaccine, “vaccine induced prothrombotic immune thrombocytopenia” (VIPIT), has been the latest complicating development, which has caused further concerns, uncertainties and confusion. The risk figures that Governments use are derived from whole population data and processed to give a smeared out average “societal” risk. But to the individuals having to make the choice, these figures may, or may not, be relevant. The corresponding societal estimate of an individual’s chance of being stuck by lightning is the well-known 1 in a million. But individuals know intuitively that for someone who never goes out in bad weather, this is way too high. Conversely someone who goes out to fly a kite in a thunderstorm has an almost certain chance of being fried. In this paper we discuss the current arguments put forward, which accept the 1 in a 100,000 as acceptable collateral damage for societal exposure. It then contrasts them against the numbers that could be derived, if it is approached from the point of view of a particular individual’s risk benefit calculations. Subsequently we discuss how communication and information by policy makers and media may influence the decisions of individuals to have or not have themselves vaccinated. While the current debate about vaccinations provides data and the central focus of this paper, the issue is a general matter, it is symptomatic of a much wider risk question which the vaccine debate has brought into focus; and not just for other vaccines and medical interventions.
Microbiological and antibiotic sensitivity pattern of surgical site infection following caesarean section in a tertiary care center of Chhattisgarh
Authors: Thakur Neha , Kujur Avinashi
Published: June 2021

Background: It is one of the most common surgery practiced in present era in obstetric population it has led to rise in postoperative morbidity in the form of surgical site infection (SSI). It not only burdens the health system but it also puts a serious negative impact on patient’s life. The present study is aimed to determine the incidence, risk factors and the microbiological and antibiotic sensitivity pattern for SSI following caesarean section in our institute.Methods: The study is prospective, descriptive study carried out in department of obstetrics and gynecology of Pt. Jawaharlal Nehru medical college, Raipur between May 2019 and April 2020.Results: Out of the 1215 participants who underwent caesarean section, 251 patients had SSI, with incidence of 20.6% among them superficial SSI (n=154) was 61.3% while deep SSI (n=75) 29.8% and 8.7% (n=22) organ/space SSI. Gram positive organism was highest isolated from superficial SSI 66.2% while from deep SSI and organ/space SSI gram positive organism isolated was 45.2% and 54.2% respectively, gram negative organisms were maximum isolated from organ/space SSI 40.9%followed by deep and superficial SSI 36% and 34.4% respectively. Most isolates were highly resistant to cephalosporins, gentamycin and amoxicillin; moderately resistant to fluoroquinolones and highly sensitive to vancomycin, carbapenem and linezolid.Conclusions: Our tertiary centre had post caesarean SSI rate of 20.6% which was high. By analyzing the microbiological and sensitivity pattern we can use evidenced-based sensitive antibiotics to be commenced initially when wound infection is identified in our wards while awaiting the result of wound swab microscopy, culture and sensitivity (48-72 hours), to individualize our antibiotic prophylaxis and postoperative antibiotic protocol policy to reduce the further complications.
Diversidad 2.0: La tecnología como aliada de las empresas latinoamericanas
Authors: Morrison Andrew , Hernández Jurado María , De la Piedra García Andrea
Published: June 2021

Hay evidencia empírica convincente de que las empresas más diversas en términos de raza, etnia y género son más innovadoras, más productivas y generan mayores utilidades. Chile, Colombia, México y Perú cuentan con la diversidad poblacional que les permitiría a sus empresas sacar provecho de las ventajas de la diversidad, pero esta diversidad no se ve reflejada en su fuerza laboral y varios estudios han documentado la discriminación sufrida en procesos de reclutamiento en las empresas privadas de tres de los cuatro países. Las tecnologías utilizadas en países desarrollados para la promoción de la diversidad parecen están entrando en una fase de madurez o declive donde ya no están generando un cambio significativo para lograr mayor inclusión y diversidad en las empresas. Por lo tanto, existe un imperativo de innovar e introducir nuevas tecnologías, para pasar a una versión 2.0 de la promoción de la diversidad. En este trabajo se hace un mapeo, a través de casos y ejemplos, de las oportunidades que ofrece la tecnología para promover la diversidad en las empresas en tres momentos de la gestión de recursos humanos: reclutamiento y selección de personal, desarrollo profesional y retención de talento y cultura organizacional. A partir de esta investigación, se concluye que las nuevas tecnologías presentan oportunidades importantes para promover la diversidad en las empresas latinoamericanas. Al mismo tiempo, no podemos dejar de lado que el uso de la tecnología presenta también riesgos éticos, sobre todo en el sentido de replicar los estereotipos y sesgos que existen en nuestras sociedades. El balance, sin embargo, es positivo. Las nuevas tecnologías tienen gran potencial para: (i) facilitar el reclutamiento de una fuerza laboral más diversa; (ii) generar datos e indicadores para visibilizar y hacer seguimiento de las brechas por género, raza y etnia en las empresas; (iii) identificar micromachismos, microagresiones y sesgos en el lenguaje, actitudes y comportamientos y ayudar a evitarlos; (iv) minimizar el impacto de los sesgos conscientes e inconscientes en los diferentes procesos de gestión de talento; (v) construir nuevos canales para medir percepciones y amplificar la voz de grupos minoritarios; y (vi) ofrecer nuevas metodologías de formación y sensibilización más efectivas que los métodos tradicionales.
Environmentally Conscious Least Cost Multi-Criteria Decision Making for Modeling Railway Network for Eritrea
Authors: Mengisti Michael , Gala Tekleab , Birru Girma
Published: June 2021

A proper development of railway transportation is critical for sustainable socio-economic and environmental benefits. Nonetheless, in Eritrea, a country that once had a vibrant railway system, it is currently nonfunctional. There are also ambitious sectoral investments in neighboring Ethiopia and Sudan, pressing Eritrea to revitalize its decimated railway transportation system. Therefore, this study used population settlement pattern, environmental and physical criteria as inputs to a least-cost multi-criteria decision-making for modeling the railway network for Eritrea. Accordingly, seven railway routes, covering a total of 1, 610 km distance, were modeled. Four are running in the north-to-south directions, while three are running in the east-to-west directions. This railway network will give services to 5 out of 6 Eritrean’s administrative regions, where 93% of the estimated 5.8 million people reside. Additionally, it will service the 21 urban centers, where an estimated population of 1,658,749 live; approximately 70% of Eritrea’s urban population. Besides, it shall boost regional integration, peace, and development thereof, in an otherwise conflict-ravaged geographical region.
Main Vectors of International Activity of the Ukrainian Greek Catholic Church
Authors: Verbytskyi Volodymyr
Published: June 2021

During the 1950s and 1980s, the Eastern Catholic Church (sharing the Byzantine tradition) was maintained in countries with a Ukrainian migrant diaspora. In the 1960s, this branched and organized church was formed in the Ukrainian diaspora. It was named the Ukrainian Catholic Church (UCC). The Galician Metropolitan Department was headed by Andriy Sheptytskyi until 1944, and after that Sheptytskyi was preceded by Yosyp Slipiy, who headed it until 1984. In addition to the Major Archbishop and Metropolitan Yosyp, this church included two dioceses (in the United States and Canada), a total of 18 bishops. It had about 1 million believers and 900 priests. The largest groups of followers of the union lived in France, Yugoslavia, Great Britain, Brazil, Argentina, and Australia. Today, the number of Greek Catholics in the world is more than 7 million.

The international cooperation of denominations in the field of resolving historical traumas of the past seems to be quite productive. An illustrative example was shared on June 28, 2013. Preliminary commemorations of the victims of the 70th anniversary of the Volyn massacres, representatives of the UGCC and the Roman Catholic Church of Poland signed a joint declaration. The documents condemned the violence and called on Poles and Ukrainians to apologize and spread information about the violence. This is certainly a significant step towards reconciliation between the nations.

The most obvious fact is that the churches of the Kyiv tradition—ОCU and UGCC, as well as Protestant churches (All-Ukrainian Union of Evangelical Churches—Pentecostals, Ukrainian Lutheran Church, German People’s Church)—are in favor of deepening the relations between Ukraine and the European Union. A transformation of Ukrainian community to a united Europe, namely in the European Union, which, in their view, is a guarantee of strengthening state sovereignty and ensuring the democratic development of countries and Ukrainian society.
Алгоритм Дейкстры для определения кратчайшего маршрута следования
Authors: Кравченко К.И. , Минеева Т.А.
Published: June 2021

В данной статье рассматривается алгоритм Дейкстры и его применение для нахождения кратчайшего маршрута. В статье описывается алгоритм Дейкстры, приводится пример программы на языке C++, позволяющей найти кратчайший маршрут.
Влияние пандемии COVID-19 на развитие дистанционных банковских услуг
Authors: Оришина В.А.
Published: June 2021

В статье исследуется влияние вспышки коронавируса на банковский сектор с учетом как краткосрочных, так и долгосрочных последствий. Оценивается готовность банковской инфраструктуры к технологиям дистанционного банкинга. Приведены примеры успешного развития дистанционных банковских услуг в ведущих банках России. Сделаны выводы о перспективах развития ДБО с учетом опыта, полученного во время пандемии COVID-19.
Классификация радиосигналов свёрточными нейронными сетями
Authors: Сафонов Н.М.
Published: June 2021

В настоящей статье представлен краткий экскурс в теоретическую и практическую сферу классификации радиосигналов с помощью метода свёрточных нейронных сетей, представление того, что такое радиосигнал, его виды и сферы применения. Оценка возможностей нейронной сети.
Automated System for Monitoring Pollutant Emissions at the Sources of Industrial Enterprises
Authors: Panarin V.M. , Maslova A.A. , Savinkova S.A. , Panarin V.M.
Published: June 2021

An automated system for monitoring emissions of pollutants at the sources of industrial enterprises is presented, capable of performing the functions of continuous monitoring in real time of the composition and volumes of emissions of pollutants into the atmosphere from stationary sources of pollution of industrial enterprises. The system is able to predict the possible onset of unfavorable environmental situations in residential areas adjacent to polluting enterprises and transmit the values of the volumes and composition of emitted pollutants to the State Fund for State Environmental Monitoring Data.
Cognitive Mechanism of Internalization in the Diary Discourse
Authors:   Saratov State University, Leonova E. V.
Published: June 2021

The article considers questions related to the way cognitive mechanism of internalization functions when an individual is developing an identity, as well as means of this mechanism being verbalized in A. Schnitzler’s personal diaries.
German Theme in N. V. Gogol’s Poem Dead Souls
Authors:   Saratov State University, Ryasov D. L.
Published: June 2021

The article regards different occurrences of Germans and Germany in Gogol’s poem Dead Souls and, consequently, the author’s own perception of German mentality during the time when he was working on the poem.
The Comparison of the Protective Effect of L-Carnitine, Chromium and Vitamin D with Metformin on Liver, Antioxidant Enzyme Activity, and Iron Metabolism in Diabetic Rats
Authors: Samani Parisa Sheikh , Shahanipour Kahin , Diziche Ali Noori , Adibnejad Mohammad
Published: June 2021

Objective: Due to the lack of information about the positive or negative effects of L-carnitine, chromium, vitamin D, and the uptake of a safe dietary supplement to reduce the effects of diabetes, it seems essential to determine the effects of these drugs on diabetes.
Materials and Methods: Wistar rats were divided into 12 groups, control, diabetic, and intact, each of which was treated with metformin, L-carnitine, vitamin D, and chromium or a combination of L-carnitine, vitamin D, and chromium. The serum levels of liver function parameters, iron, TIBC, Catalase and GPX activities were measured. Data were statistically analyzed by one-way ANOVA using SPSS 18 software. Statistical significance among the groups was determined using LSD test, and P-value< 0.05 was considered significant in all cases.
Results: AST activity in diabetic groups and those receiving chromium and L-carnitine has significantly reduced (P-value= 0.009). A significant reduction in ALT and ALP activity in the diabetic groups receiving vitamin D and combined and non-diabetic groups receiving metformin were observed, in contrast to a significant increase in ALT activity in diabetic recipients of Lcarnitine (P-value= 0.009).
Conclusion: L-carnitine, chromium, and vitamin D supplements have synergistic effects and a combination of them has the best protective effect on factors that have been studied.
Comparison of the Agouti Dependent Protein and Neuropeptide Y Response to the High Intensity Interval Training in Obese and Underweight Men
Authors: Akbarpour Beni Mohsen , Fathollahi Shoorabeh Fazlollah , Mardanian Mohammad Reza , Samari Ebrahimzadeh Zahra
Published: June 2021

Objective: Appetite regulation has a great impact on energy homeostasis. This study aimed to compare the response agoutirelated protein (AGRP) and neuropeptide Y (NPY) to a single high intensity interval training (HIIT) in obese and underweight men.
Materials and Methods: This semi-experimental research conducted on 40 obese and underweight men who were divided into four groups including experimental groups (10 obese, and 10 underweight men) and control groups (10 obese, and 10 underweight controls). Both groups were evaluated by biochemical measurements in two stages of pre-test and post-test. HIIT was carried out to the experimental groups during one session. Data were analyzed using one-way ANOVA and T-test using SPSS 21 software.
Results: NPY levels showed a significant difference in pre and post-test in both experimental groups, NPY increased 6.14% in obese men and 25.50% in underweight men, which was significant in both obese (P-value= 0.002) and underweight (P-value= 0.007) groups. In addition, AGRP levels increased 1.91% in obese men and 6.65% in underweight men, although this was not significant (P-value= 0.098). However, no significant differences were observed among groups in the levels of NPY and AGRP (P-value= 0.114).
Conclusion: The results of the present study showed that HIIT can increase the amount of AGRP and NPY in obese and underweight men. Therefore, appetite neuropeptides increase after a training session, which should be considered in the balance of energy and food intake after exercise.
Fauna and Larval Habitat Characteristics of Mosquitoes (Diptera: Culicidae) in Kashan County, Central Iran, 2019
Authors: Asgarian Tahereh Sadat , Moosa-Kazemi Seyed Hassan , Sedaghat Mohammad Mehdi , Dehghani Rouhullah , Yaghoobi-Ershadi Mohammad Reza
Published: June 2021

Background: Mosquitoes are responsible for spreading devastating parasites and pathogens causing some important infectious diseases. The present study was done to better understand and update the fauna of Culicidae and to find out the distribution and the type of their larval habitats in Kashan County.
Methods: This study was done in four districts of Kashan County (Central, Qamasr, Niasar and Barzok). Mosquito lar-vae were collected from 23 active larval habitats using a standard 350ml capacity mosquito dipper from April to late December 2019. The collected larvae were transferred to containers containing lactophenol, and after two weeks indi-vidually mounted in Berlese's fluid on a microscope slide and identified to species by morphological characters and valid keys.
Results: In this study, a total of 9789 larvae were collected from urban and rural areas in Kashan County. The identified genera were Anopheles, Culiseta and Culex. In this study larvae of An. turkhudi, Cx. perexiguus, Cx. mimeticus, Cx. deserticola and Cs. subochrea were collected for the first time from Kashan County.
Conclusion: The results of this study indicate the presence and activity of different mosquito species in Kashan County that some of them are vectors of arbovirus and other vector-borne diseases.
Community pharmacies and pharmacists in Brazil: A missed opportunity
Authors: Melo Angelita C. , Trindade Guilherme M. , Freitas Alessandra R. , Resende Karina A. , Palhano Tarcísio J.
Published: June 2021

The Brazilian National Health System (BR-NHS) is one of the largest public health systems in the world. In 2019 Brazil had 114,352 community pharmacies (76.8% private owned), that represent the first point of access to healthcare in Brazil due to their wide distribution. Unfortunately, from the government's point of view, the main expected activity of private and public community pharmacies is related to dispensing medicines and other health products. Public community pharmacies can be part of a healthcare center or be in a separate location, sometimes without the presence of a pharmacist. Pharmacists working in these separated locations do not have access to patients’ medical records, and they have difficulty in accessing other members of the patient care team. Pharmacists working in public pharmacies located in healthcare centers may have access to patients’ medical records, but pharmacy activities are frequently under other professional’s supervision (e.g., nurses). Private pharmacies are usually open 24/7 with the presence of a pharmacist for 8 hours on business days. Private community pharmacies have a very limited integration in the BR-NHS and pharmacists are the third largest healthcare workforce in Brazil with more than 221,000 registered in the Brazilian Federal Pharmacist Association [CFF - Conselho Federal de Farmácia]. A University degree in pharmacy is the only requirement to entry into the profession, without any proficiency exam for maintenance or career progression. The Brazilian pharmacist's annual income is ranked as the 2nd better-paid profession with an annual average income of € 5502.37 (in 2020). Description of clinical activities for pharmacies by the CFF increased in the recent years, however there is still a long way to effectively implement them into practice.
Goods road transport sector facing pandemic crisis
Authors: Banaszyk Piotr , Konecka Sylwia , Maryniak Anna
Published: June 2021

Purpose: The aim of the study is to indicate the scope and intensity of the COVID-19 pandemic impact on the goods road transport companies’ performance and to indicate how the dedicated “support system” should work. Design/methodology/approach: The research was conducted with the use of a structured electronic questionnaire, primarily via the Intranet. In order to obtain high-quality research, the respondents were guaranteed anonymity and the data was presented in a collective agreement. Findings: On the basis of the conducted research, we found that as a result of the crisis situation the most destabilized became the transport carried out in the international space. The most important problems – out of the eighteen assessed – include a decrease in orders and a reduction in shipping rates, which with the low profitability of the industry, resulted in: serious problems in financial liquidity; retaining employees; and low levels of cooperation in the supply chain, especially concerning smaller service providers. In order to strengthen the competitiveness on the market, future strategies will focus more on the differentiation of transport services in terms of products and geography and on the regionalization of activities. We should assume that all previous predictions from month to month will be increasingly optimistic, and there will be anoticeable dynamic increase in road transport, driven by the growing demand of all sectors of the economy in need of logistics services and resulting also from the broader entry of non-European markets. Research limitations/implications: The research was conducted using the survey method, i.e. based on the opinions of respondents. The responses were often emotional in nature. Practical implications: The text includes proposals for the expected external support for the transport industry. Originality and value: The results are one of the first studies of the transport industry in Poland during the pandemic crisis. Information may be important to industry and central government representatives.
Donation crowdfunding as a source of relief for small businesses
Authors: Wieczerzycki Marcin
Published: June 2021

Purpose: The purpose of this chapter is to examine advantages and limitations of donation crowdfunding as away of providing relief for small businesses and assessing its potential development in that field in the post-pandemic future. Design/methodology/approach: The chapter is based on critical literature analysis, supported by empirical examples for illustrative purposes. Findings: Donation crowdfunding can be aviable way of providing relief to small companies during the times of crisis, by positioning companies as beneficiaries of charitable endeavors carried out by consumers. Practical implications: Companies ability to trigger altruistic responses in their consumers is an important information in times of crises. Moreover, the information serves as an additional argument for building meaningful relationships with consumers and establishing locally embedded or virtual communities, which make securing relief through donation crowdfunding easier. Originality and value: The subject of using donation crowdfunding by companies to secure relief funds has seen very limited elaboration in the current literature.
Aura de amor sobrenatural (de Apolonio de Tiana a Carlos Fuentes)
Authors:   Universidad Nacional Autónoma de México, Instituto de Investigaciones Filológicas, Chaves José Ricardo
Published: June 2021

In this essay the comparative follow-up of the motive of the dis / encounter of lovers belonging to different ontological fields (life / death, wakefulness / sleep), expressed in fantastic figures such as empusas, ghosts and vampires is carried out. The starting point is a story of Apollonius of Tiana according to the text of Philostratus, which was recovered by Goethe in The Bride of Corinth, taken up by 19th century authors such as Théophile Gautier and Amado Nervo, and reworked by Carlos Fuentes in the 20th century, in his novel Aura, with the addition of an 18th century Japanese author, Ueda Akinari, who wrote stories along these lines.
Russian social reality on the eve of a new stage of the State Duma work
Authors: Merzlikin Nikolay
Published: June 2021

Review of a research: Rossiiskoe obshchestvo i gosudarstvo v usloviyakh pandemii: sotsial’no-politicheskoe polozhenie i demograficheskoe razvitie Rossiiskoi Federatsii v 2020 godu [Russian society and state in a pandemic: the socio-political situation and demographic development of the Russian Federation in 2020] / Osipov G.V. [et al.]; ed. by G.V. Osipov, S.V. Ryazantsev, V.K. Levashov, T.K. Rostovskaya; otv. red. V.K. Levashov. M.: PERSPEKTIVA Publ., 2020. 532 p. ISBN 978-5-905790-48-5. DOI 10.38085/978-5-905790-48-5-2020-1-532.The main event of 2020, which determined the situation in the world and in Russia, was the COVID-19 pandemic. The influence of the covid crisis, directly or indirectly affected all spheres of life in Russian society, reflected on the functioning of government institutions and public organizations, on the nature of relations between civil society and the state. The structure and procedure for the formation of national goals and programs were rethought, society reacted more meaningfully and responsibly to assessing the current state and ways of developing the Russian economy and social sphere, in particular, to the healthcare sector. The explosive growth of various forms of digital communications under conditions of forced self-isolation made it possible to assess the socio-political aspects of the digital transformation of Russian society in a new way, more competently, and to substantively investigate the challenges and threats that the process of shaping the digital future entails.In the context of large-scale socio-political changes, the importance of studying the key trends in the development of the global world and Russian society, a comprehensive analysis of the spheres of life of Russian society: socio-political, socio-economic and socio-demographic is growing. These are the tasks set for themselves by the authors of a scientific monograph prepared by scientists from the Institute for Social and Political Research and the Institute for Demographic Research of the Federal Research Center of the Russian Academy of Sciences based on the results of research in 2020.
Where do they lead Ukraine?
Authors: Busygin Andrey
Published: June 2021

Review of the scientific report of the Institute of Sociology of the National Academy of Sciences of Ukraine: Where is Ukraine going in the 21st century? Social changes in Ukrainian society in the context of economic globalization: sociological dimension. Scientiﬁc report/ T.Petrushyna, A.Arseienko, V.Butkaliuk. Kyiv: Institute of Sociology, National Academy of Sciences of Ukraine, 2020. 120p. ISBN 978-966-02-9424-0.
The authors of the report set themselves a goal: to give the most complete and holistic picture of the processes taking place today in Ukraine in the context of global social changes in a concise form, in order not only to convey their conclusions to the scientific community, but also to inform the general public and the authorities about the real situation in the country. And the real situation, according to the authors of the report, "threatens the ability of our state to reproduce its sovereignty and ensure the preservation of the country's territorial integrity".
The impression after reading the report is such that it is still putting it gently about threats! Not even gently, but veiled. Indeed, the words about Ukraine's inability to reproduce its sovereignty and ensure the preservation of the country's territorial integrity are a euphemism for stating Ukraine's dying, sliding towards ruin, towards death. And not because Russia or some other state will dismember it, but because the state's economy is withering, the social sphere is deteriorating, the population is becoming impoverished, young people are leaving to live abroad, and, ultimately, Ukraine is dying.
Interest of Moscow Youth in Non-Traditional Religions, Eastern Religions and Esoteric Teachings
Authors:   ИДИ ФНИСЦ РАН, Москва, Россия, Лютенко И. В.
Published: June 2021

This material analyzes the empirical indicators of sociological research in the Moscow metropolis, conducted in 2018 and 2020. The research data characterize the interest of young people in alternative religions and esoteric teachings, the involvement of the practices of these views in the everyday life of young people.
Investigation of clinical and laboratory manifestations of rheumatoid arthritis depending on the level of serum fetuin-A
Authors:   Research Institute of Clinical and Experimental Rheumatology named after A. B. Zborovsky, Papichev E.V. , Zavodovsky B.V. ,   Research Institute of Clinical and Experimental Rheumatology named aft er A. B. Zborovsky, Sivordova L.E. ,   Research Institute of Clinical and Experimental Rheumatology named aft er A. B. Zborovsky, Akhverdyan Yu.R. ,   Research Institute of Clinical and Experimental Rheumatology named aft er A. B. Zborovsky, Polyakova J.V. ,   Research Institute of Clinical and Experimental Rheumatology named aft er A. B. Zborovsky
Published: June 2021

Aim of the study. To study the association between the serum FA in patients with RA and separate clinical and laboratory manifestations of the disease. Material and methods. A total of 140 subjects were enrolled in the study. Among them, 110 were RA patients and 30 were conventionally healthy subjects. Th e level of serum FA was measured in both groups. All patients underwent complete clinical and laboratory examination and X-ray imaging of the impaired joints. Results. The level of normal FA in healthy subjects calculated as M±2σ totalled 653.55-972.19μg/ml. The mean level of FA in RA patients was 765.67±120.67μg/ ml, which is statistically lower than that in the donors: 812.95±76.21μg/ml (t=-2.03; p=0.0437). Th e mean FA level in conventionally healthy patients was statistically higher than the same index in RA-factor positive patients with cyclic citrullinated peptide antibodies, moderate and high activity, late clinical stage, X-ray stages III and IV, functional classes II, III and IV, joint erosion, abarticular manifestations and the presence of complicating diseases. Intra-group analysis (odds ratio and adjusted odd ratio) showed the patients with lower FA level (below 653.55μg/ml) to have a 14-fold higher possibility of CCP antibodies positivity (6-fold after adjustment), 1.86-fold higher disease activity (2.39-fold aft er adjustment), 6.6-fold higher probability of X-ray stage IV (with no statistical signifi cance after adjustment) and 29-fold higher chance of presence of complications (46-fold after adjustment). Conclusion. According to the data obtained in our study, lowering of the serum FA level is characteristic to RA patients. The hepatokine concentration below 653.55μg/ml may suggest 2.39-fold higher chance of higher disease activity and 46-fold higher probability of complicated RA progression.
Nanoscalpel based on magnetic discs and aptamers effectively and targeted destroy tumor cell
Authors:   Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Science, Zamay S.S. , Prokopenko V.S. ,   V.P. Astafiev Krasnoyarsk State Pedagogical University, Lukyanenko K.A. ,   Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Science, Sokolov A.E. ,   Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Science
Published: June 2021

The aim of the research. To investigate the antitumor effi cacy of three-layer magnetic nanodiscs (Au / Ni / Au) with a quasi-dipole structure, functionalized with biorecognizing molecules of a tumor. Material and methods. Th ree-layer magnetic nanodiscs (Au / Ni / Au) 500 nm in size (were obtained by micro- and nanoelectronic technologies. Aptamers to ascites cells of Ehrlich carcinoma were used to functionalize magnetic nanodiscs. Th iol groups were used to bind disks to aptamers. As a model of tumor cells Ehrlich’s ascites carcinoma cells were used, and the cells were magnetically infl uenced by an alternating magnetic fi eld (50 Hz, 100 Oe). Results. Magnetic nanodiscs have magnetic anisotropy, which proves their high sensitivity to magnetic stimuli. Magnetic nanodiscs start the processes of cell death in the culture of ascites cells for two hours. Presumably, magnetic nanodiscs use aptamers to bind to the cell membrane protein fi lamin A, a structural component of the cytoskeleton that plays an important role in cell signaling and, when exposed to a variable magnetic, cause destruction of the cell membrane and cell death. Conclusion. Microsurgery of malignant tumors using a nanoscalpel based on functionalized ligands that recognize tumor sites can be used to remove single tumor cells during surgery
Circulating tumor cells: real-time monitoring of the course of breast cancer
Authors:   Professor V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Zyuzyukina A.V. , Vatrushkina M.O. ,   Professor V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Zukov R.A. ,   Professor V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Published: June 2021

The aim of the research. Th is study aims to determine the content of circulating tumor cells (CTCs) in the peripheral blood using the MDA 231 aptamer in the dynamics of the disease. Material and methods. Th e study included 6 patients with breast cancer, who have been under dispensary supervision since 2017. Detection of CTCs was carried out in 3.5 ml of the blood of BC patients with the help of the MDA 231 aptamer which is affi ne for breast cancer cells, labeled with the fl uorescent Cy-5 dye. Th e count of CTCs in the blood samples was performed using fl uorescent and laser scanning microscopy. Results. Using the MDA231 aptamer, the content of CTCs in the peripheral blood of patients with breast cancer in the dynamics of the disease was analyzed. CTCs were detected in 1 patient, who was subsequently diagnosed with metastatic liver damage. Conclusion. Th e study demonstrates the possibility of using aptamers to determine the risk of relapse and to evaluate the eff ectiveness of antitumor therapy in patients with breast cancer.
Social and cultural foundations of University transformation in Online Society
Authors:   Dubna State University, Voinova A.A. , Kirillov P.E. , Ryabtsev S.V.
Published: June 2021

Examined is the issue of the further trajectory of the university development in modern society, where information and technological transformations determine a completely new educational discourse. It is emphasized that the cognitive nature and the increasing role of knowledge and education as the most important value are becoming the main characteristics of the new society. At the same time, the main factor of modern production, in contrast to the previous social forms, turns out to be inseparable from its subject. Knowledge constructs a person, becomes his leading characteristic. As a result, investments in people are growing: expenses for training and education, advanced training and retraining of employees. Information and knowledge in their new role create the socio-cultural context in which modern education exists, including university education. The thesis is substantiated that the philosophical understanding of education in a new society proceeds from an understanding of the specifics of the modern world and the position of a person in it. Since today a knowledge worker with a talent for assimilating information from various sources and transforming it into new knowledge is in demand, the university is guided by this idea in choosing its strategy. At the same time, the focus of attention is all the same knowledge as a leading public and personal resource, however, the new specificity of educational knowledge, as knowledge that is the subject of the university’s activity — its informational variability, fragility and contextuality, due to global informatization, cannot but affect comprehension of the specifics of a modern university.
Organization of project activity of children with disabilities under conditions of FGOS (example of rural medium school in Novosergievsk district of Orenburg region)
Authors:   Municipal educational budget school “Suzanovsk medium educational school”, Pakhar V.V. , Pakhar E.I. , Pakhar V.A.
Published: June 2021

Examined is the problem of development of children with disabilities by means of project activity with reckoning of Federal state educational standard (FGOS). Described is project activity, dealt with children with disabilities on the base of rural school in Novosergeevsk district of Orenburg region. Summerized are results and also made conclusions as to the research work.
Dominant work motives of Russian employees in the second decade of the 21st century
Authors:   Lobachevsky State University of Nizhny Novgorod, Prokhorova M.V. , Kravchenko V.S. , Barankina A.E. , Shamina O.S.
Published: June 2021

Revealed are dominant work motives of Russian employees in the second decade of the 21st century. The authors are based on a two-modal concept of work motivation, the foundations of which were laid by F. Herzberg, highlighting positive and negative labor motivation as independent structures. It was elicited that the core of positive labor motivation is the following: high wages, interesting work, stable and reliable work. In the structure of negative labor motivation, the dominant motive is low wages, the second and third levels are formed by unstable and unreliable work, poor working environment. The study, which was attended by 759 respondents, had being conducted from 2012 to 2020. The questionnaire “Ranking of positive and negative work motives” (RPOM) was applied to collect data. Their processing was carried out using methods of descriptive statistics, non-parametric U test, Mann-Whitney, as well as qualitative analysis.
Features of social adaptation of ethnic groups in modern conditions
Authors:   Sumgait State University, Badalova N.S.
Published: June 2021

Discussed are actual questions of a sociological analysis of the social adaptation of various ethnic groups, since globalization disrupts the natural course of this process. We consider it important to preserve the ethnic identity of each nation, subject to their active participation in modern general civilizational development, in order to make a worthy contribution. In order to identify the characteristic features of social adaptation of ethnic groups, two were selected: Khinalugs and Talyshs. The method of analyzing the history of the development and formation of these peoples and the modern conditions of their life revealed the characteristic features of social adaptation here. The considered facts and tendencies in the vital activity of the indicated nationalities gave grounds to draw the following conclusions. In the life of the Hinalugians, their geographical isolation from the rest of the world played a decisive role, which helped them to preserve their unique language and way of life. Now, thanks to the expanded possibilities of communication, this village is exposed to the active influence of the outside world, which fundamentally changes the nature and possibilities of social adaptation of each subsequent generation of people. The Talyshs, being a larger ethnic unit, were subjected to assimilation and other influences of the external world more actively. Despite this, they managed for many decades to preserve their originality. In the modern era of globalization, the general social processes actively influence the process of their social adaptation. Thus, the self-consciousness of the ethnos is destroyed, the self-consciousness of the national identity is formed.
In search of tolerant paths in renewing of the World
Authors:   Grozny State Oil University n.a. аcad. M.D. Millionshtchikov, Umarovа Z.Ya.
Published: June 2021

Discussed is the problem of search for tolerant paths in the spiritual renewal of the world. The modern world is oppressed by a person and forces to admit that he did not choose this world in goodwill, in which a lie, hypocrisy, meanness, envy, hatred, betrayal. The need to rise to a higher level of knowledge of the world in relationships and mutual understanding of people is the requirement of time. It is important through the tolerant consciousness to find bonding paths leading to spiritual unity with all people of the planet. The technique creates convenience, but also lead to the crisis of human relations. It cannot specify the value guidelines, reveal the soul of the person and fill the content of those kind basements, without which the human life does not make sense. It is necessary to find ways in the modern world uniting all people and expand their intellectual and moral possibilities, through education and culture
Studi Literatur: Pengaruh Fungsi Kognitif Terhadap Activities of Daily Living Pasca Stroke
Authors: Sandrawati Dewi Putri
Published: June 2021

Latar Belakang: Serangan stroke dapat menghambat aliran darah ke bagian otak tertentu yang menyebabkan sebagian dari otak tidak mendapatkan nutrisi dari aliran darah sehingga mengakibatkan kerusakan pada bagian otak yang terdampak. Kerusakan otak akibat stroke dapat meningkatkan risiko penurunan fungsi kognitif sehingga pasien pasca stroke menjadi bergantungan pada orang lain dalam melakukan aktivitas sehari-hari atau activity of daily living (ADL).   Tujuan: Penulisan artikel ini bertujuan untuk mendeskripsikan pengaruh fungsi kognitif terhadap kemandirian activities of daily living (ADL) pada pasien post stroke.  Metode: Metode penulisan ini adalah studi literatur dengan menggunakan sumber pustaka jurnal dan buku referensi yang mendukung penulisan artikel ini. Hasil: Hasil yang diperoleh menurut sebagian besar penelitian terdapat korelasi yang positif antara gangguan kognitif dengan kemandirian activities of daily living (ADL). Namun ditemukan pada salah satu penelitian yang menyatakan bahwa tidak terdapat hubungan yang signifikan antara fungsi kognitif yang diukur dengan The Mini-Mental State Examination (MMSE) dengan basic activities of daily living (BADL).Kesimpulan: Stroke dapat menyebabkan gangguan kognitif yang dapat mempengaruhi kemandirian activity of daily living (ADL) pada pasien pasca stroke dan gangguan kognitif pada domain persepsi memiliki pengaruh yang besar pada kemampuan pasien dalam melakukan activity of daily living (ADL).
Literature Review: The relationship of the physical quality of the environment in the dwelling to the incidence of Acute Respiratory Infection (ARI)
Authors: Nur Aryanti Rismaya Fika
Published: June 2021

Background: Acute Respiratory Infection (ARI) is a disease transmitted by viruses. This health problem persists from year to year, starting from developing countries to developed countries there are still morbidity and mortality rates due to ARI. One of the factors that can affect human health is environmental factors which include occupancy density, ventilation area, natural lighting, humidity, temperature, conditions and types of walls, and floors.Purpose: This literature study aims to analyze the relationship between the physical quality of the occupancy and the occurrence of acute respiratory infections (ARI).Reviews: The results of the journal search were found as many as 17 journals that met the inclusion criteria set by the researcher. Most of the research found used a cross sectional study design, but some studies also used case control and cohort study designs. Several different results were found for each study, but still showed similarities, namely the incidence of ARI in each study.Conclusion: The journal review that has been conducted can conclude that there is a relationship between the area of ventilation, humidity, temperature, natural lighting, occupancy density, conditions and types of walls, as well as conditions and types of floors. There are differences from each of the research results, but there are still similarities which state that there is a relationship between the physical quality of the environment at home and the incidence of ARI.
PENGAPLIKASIAN TEORI PRECEDE PROCEED DALAM UPAYA PEMBERDAYAAN MASYARAKAT DI KELURAHAN SIDOTOPO
Authors: Mandasari Amalia Ayu
Published: June 2021

Latar Belakang: Sebuah pemberdayaan masyarakat berguna untuk memampukan dan memandirikan masyarakat. Dimana begitu banyak permasalahan masyarakat yang ada, salah satunya permasalahan kesehatan, seperti  lingkungan yang tercemar oleh sampah. Permasalahan akibat sampah dapat berdampak pada 25% ikan yang mengandung plastik, 80% sampah yang berada di laut merupakan sampah dari darat, merusak lingkungan sekitar, menyebabkan penyakit seperti disentri dan DBD serta dapat juga menurunkan derajat kesehatan masyarakat yang bermukim di wilayah tersebut. Salah satu wilayah yang mengalami permasalahan sampah adalah Kelurahan Sidotopo, tepatnya di wilayah RW XI, Kota Surabaya.Tujuan: Untuk membantu masyarakat RW XI agar dapat meningkatkan kesadaran tentang kesehatan lingkungan serta memampukan masyarakat untuk menanggulangi permasalahan yang ada pada lingkungannya. Metode: Proses pemberdayaan masyarakat RW XI Kelurahan Sidotopo Kota Surabaya dengan sasaran penelitian masyarakat yang memiliki balita dan dilakukan pada tanggal 26 Desember 2019 hingga 31 Januari 2020. Metode yang digunakan yaitu dengan metode deskriptif kualitatif dengan design cross sectional dan untuk melakukan implementasi menggunakan kerangka teori precede proceed.Hasil dan Pembahasan: Hasil penelitian berupa masyarakat dapat terbantu untuk meningkatkan kesadaran tentang kesehatan lingkungan serta memampukan masyarakat untuk menanggulangi permasalahan yang ada pada lingkungannya.Kesimpulan: Pembentukan kebijakan oleh masyarakat sekitar dan pembentukan laskar sebagai pelopor kesehatan masyarakat di wilayah RW XI Kelurahan Sidotopo Kota Surabaya.