bluuebunny/crossref_metadata_2025 huggingface dataset:
Resistance to Azole Compounds in ENT and Genital Infections Produced by Candida Species
Authors: Rusu Elena , Moldovan Cosmin Alec , Mitache Magdalena Mihaela , Niculae Mirela , Popescu Georgeta Gilda , Nemes Roxana Maria
Published: January 2020

Candida albicans species is located in the oral cavity, digestive tract and genital region as the commensal flora in more than half of the healthy population. Infection with species of Candida genus is the most common cause of vaginal infections, second only to bacterial vaginitis. Candida albicans species is ubuquitous commensal yeast that develops in the mucous membranes. Under normal conditions of host health, this microorganism is in balance with the microbiota of these areas but also with the host�s immune system.
The aim of this study was to determine and compare the sensibility and the resistance of some Candida albicans strains isolated from oro-pharyngeal and vaginal secretions to different azole compunds. In the case of oro-pharyngeal infections, most of the Candida isolated species were resistant to ketoconazole, itraconazole and fluconazole and in the case of isolated species in vaginal infections the resistance was increased in the case of fluconazole, itraconazole and ketoconazole, in different percentages compared to oro-pharyngeal site.
Reducing the Duration and Improving Hospitalisation Time by Using New Surgical Tehniques and Psychotherapy
Authors: Toma Andra Georgiana , Salahoru Paul , Hinganu Marius Valeriu , Hinganu Delia , Dima Cozma Lucia Corina , Patrascu Alexandru , Grigorescu Cristina
Published: January 2020

As far as surgical techniques are concerned, video-assisted thoracoscopy comes with lot of improved results compared to classical surgical techniques. This technique seems to reduce the parameters reflecting the period of hospitalization, exposure to analgesics, patient�s recovery rate, and the level of pain felt. Studies have been conducted that have demonstrated that, hypnosis can significantly improve the duration of pain exposure as well as the intensity perceived by the patient. In domain literature report cases in which hypnosis has been proven effective is in the preoperative preparation of surgical patients. furthermore, by applying hypnosis, positive results are found during the postoperative care of patients. This study aims at the results of video-assisted surgical techniques, and at the opportunity of integrating complementary therapeutic elements such as hypnosis to improve the parameters interested in perioperative care of the surgical patient.
Researches Regarding the Reduction of Oxidation Losses in the Obtaining of Secondary Aluminium Alloys Using Metallic Scraps
Authors: Apostol Constantin , Butu Mihai , Dobrescu Cristian , Tache Alexandra
Published: January 2020

The paper presents thermodynamic aspects regarding the low temperature processing of small metal waste - aluminum alloy scraps. The activation energies of oxidation reactions of aluminum and some alloying elements with water vapors, carbon dioxide and oxygen present inside the furnace are compared, at the usual and experimentally temperatures (at 580 � 620oC, near the eutectic temperature, when the melt is in the semisolid/pasty state), in the elaborating of EN AB 46100 secondary alloys. The composition of the flue gases is presented at different temperatures and during different technological stages. Using electronic microscopy and EDS analysis, the elemental composition of the impurities resulted from the melt is highlighted.
Study on the Behavior of Dental Alloy CoCrWNbMoV in Artificial Saliva
Authors: Alexandru Adrian , Cimpoesu Ramona , Melian Anca , Salceanu Mihaela
Published: January 2020

Dental materials represent an important market worldwide. For solutions that are currently financially acceptable, CoCr or CoCrMo alloys have been an affordable option for all dental technicians. Constant improvements in the properties of this alloy such as corrosion resistance and hardness have been pursued. In this paper are presented some experimental results obtained from the electro-corrosion resistance analysis of the CoCrWNbMoV alloy in two electrolyte solutions made from artificial saplings Afnor and respectively Duffo Quezada. Following electro-corrosion resistance tests, the surface of the alloy was characterized by optical and electron microscopy (OM and SEM) and chemical dispersion X-ray (EDS) analysis.
Biochemical Variations of Breast Milk Composition Compared with Substitution Formula in Feeding of Preterm of Mothers With or Without Pathologic Pregnancies
Authors: Biris Marius , Gluhovschi Adrian , Noditi Georgeta , Iacob Daniela , Craina Marius , Anastasiu Doru , Anastasiu Popov Diana Maria
Published: January 2020

Breast milk is the main source of energy and nutrients for preterm and term newborns. The aim of the study was to determine the biochemical differences between breast milk and substitution formula used in feeding of preterm newborns and differences in composition of breast milk according to mothers demographic and pregnancy parameters. A group of 54 mothers with pathologic pregnancies of preterm gestational age between 27-37 weeks was studied to determine the biochemical composition of breast milk in the first 7 days of lactation and then to compare it with milk formula substitution. Most of them (42%) had a diagnosis of chronic hypertension, followed by chronic renal diseases (29%). Several parameters like gestational age, maternal age, lactation day when sampling milk, type of birth (natural / C-section), origin of mother (rural / urban), gender of the child were analyzed. The biochemical analysis of macronutrients (carbohydrates, lipids, proteins) and energetic value of the collected breast milk was performed by using an indirect method, infrared spectroscopy (mid-infrared transmission spectroscopy) by means of an automatic device. Gestational age, mother�s age and day of lactation (during the first week post-partum) did not produce a statistically significant difference in the composition of breast milk. There were no statistically significant changes with the type of delivery (cesarean versus natural) and gender of the preterm newborn. Higher lipid, carbohydrates and protein concentration was observed in milk substitution formula than in breast milk. Energetic values of analyzed milk substitution formula showed a statistically significant difference (p [0.05) when compared with breast milk.
Ursodeoxicholic Acid in the Treatment of Intrahepatic Cholestasis of Pregnancy
Authors: Timircan Madalina Otilia , Hogea Lavinia Maria , Cirlogea Andreea , Cojocaru Ioana , Zorzoana Irina , Nussbaum Laura Alexandra , Folescu Roxana , Hogea Bogdan Gheorghe , Simu Mihaela , Pascu Alina Mihaela , Boanca Mihaela , Gomoi Evelina
Published: January 2020

Intrahepatic choleastasis of pregnancy (ICP) also called obstetric cholestasis (OC) is a liver condition of pregnancy characterized by pruris, elevation in circulating bile acide and liver derangement, associated with adverse fetal outcomes such as preterm labor and stillbirth. The frontline treatment for ICP is Ursodeoxicholic acid (UDCA). This medication has been shown to be superior to all other medications in the treatment of ICP, and has been proved safe for both mother and baby.
Structural and Magnetic Properties of the Rapid Cooled Alloys: Fe60Co10Y5+xZr5-xB20 (Where: x = 0 or 2)
Authors: Nabialek Marcin , Jez Bartlomiej , Jez Kinga , Bloch Katarzyna
Published: January 2020

This article presents the results of tests on high-temperature alloys, produced on the basis of the FeCoB matrix. The nanocrystalline material was produced in a single-step process of rapid cooling of liquid alloy that was injected into a copper mould. Alloy samples were obtained in the form of 10mm x 5mm x 0.5mm tiles. Studies of the structure of the manufactured alloys were undertaken using Bruker X-ray analysis equipment (featuring a CuKa lamp). The magnetic polarization of saturation was measured, as a function of temperature, using a Faraday magnetic balance; the measurements ranged from room temperature up to 850K. Through numerical analysis of the curves, the Curie temperature of the investigated alloys was determined. Using a vibration magnetometer, static magnetic hysteresis loops were measured. The magnetization of saturation of the tested alloys was greater than 1 T, while the coercive field values were 400 and 16600 A/m. The stiffness parameter of the spin wave Dspf was determined.
Performance Evaluation of Continuous Flow Aerobic Granular Sludge Configurations
Authors: Manea Elena Elisabeta , Bumbac Costel
Published: January 2020

Increasing the efficiency and capacity of existing wastewater treatment plants can be carried out by using intensive biological processes. One of the currently studied biological solutions consists in using aerobic granular sludge in order to achieve both organics and nutrients removal simultaneously in one tank and with high efficiency. Aerobic granular sludge is currently used at full scale in sequential batch reactors, research for identifying the optimal solutions for continuous flow systems being carried out worldwide. The paper summarizes the results obtained for two continuous flow configurations with aerobic granular sludge, in terms of organics and nutrients removal for synthetic wastewater in laboratory conditions. Both experimental setups led to wastewater treatment efficiencies, with values ranging between 80 and 99% for COD, 85 and 99% for BOD5, 52 and 98% for NH4+ and 5 to 87% for TP.
Ecotoxicity of Biocides (Chemical Disinfectants) - Lethal and Sublethal Effects on Non-target Organisms
Authors: Gheorghe Stefania , Stoica Catalina , Lucaciu Irina , Banciu Alina , Nita Lazar Mihai
Published: January 2020

The aim of this paper was to assess de ecotoxicity effects of four biocides, used as chemical disinfectants for swimming pool water treatment, on non-target organisms such as Daphnia magna and Heterocypris incongruens crustaceans. The tests showed a significant difference of sensitivity between species. The biocides, at the recommended disinfection doses, induced a very toxic or toxic effect on Daphnia magna, based on their mortality percentage. On the contrary, the observed ostracods lethal effects were generally less than 50% mortality and no significant growth inhibitions were observed. Overall, the ostracods had a higher tolerance to subacute doses, including disinfection doses of 20 mg/L (potassium mono persulfate), 5 mg/L (sodium dichloroisocyanurate), 8 mg/L (trichloroisocyanuric acid 90%) and 7 mg/L (trichloroisocyanuric acid 87-88%). In the context of a continuous biocides market expansion, the paper highlighted that our research proposed testing methods to obtain fast and accurate ecotoxicity data for a sustainable biocide production / authorization and also for an environmental hazard assessment.
Nocturnal Hypoxemia, a Key Parameter in Overlap Syndrome
Authors: Budin Corina Eugenia , Maierean Anca Diana , Ianosi Edith Simona , Socaci Adriana , Buzoianu Anca Dana , Alexescu Teodora Gabriela , Olteanu Mihai , Rusu Elena , Moldovan Cosmin Alec , Nemes Roxana Maria
Published: January 2020

The overlap syndrome (OS) is defined as a synergic relation between obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD). Patients with overlap syndrome present the clinical features of each disorder to a greater or a lesser extend depending on the predominant disease. We assessed the main differences between patients with OS and patients with OSA and we highlight the importance of nocturnal hypoxemia on clinical status and management of the patients with overlap syndrome, in order to simplify OSA screening tests in patients with COPD. The study population included 62 selected patients divided in two groups: the first group � subjects diagnosed with OS and the second group - subjects with OSA, without the diagnostic of COPD. The majority of the patients were male, with a mean age of 55�9.84 years in the OSA group and 65.5�10.32 years in the OS group. The nocturnal hypoxemia was more important in the OS grup, with 276.83 minutes spent at a SpO2 below 90% versus 132.98 minutes in the OSA group. The mean AHI was 57.7�29.244 events/hour of sleep in the OS group and 50.7�26.01 events/hour of sleep in the OSA group. At the diagnosis, the mean daytime SpO2 was 90.9�3.59% in the OS group and 95.9�1.57 % in the OSA group. There were statistically significant differences between the two groups concerning age, AHI, Epworth Slepiness Scale, nocturnal desaturation, medium and minimum SpO2 during sleep, daytime SpO2 at the diagnosis and at 1-year follow-up, the presence of cardiovascular comorbidities such as pulmonary hypertension and heart failure. Our study showed that patients with COPD have OSA predictors that differ from those usually recognise in the general population. In OS patients, the most important parameter is the nocturnal hypoxemia. So, it is very useful that the clinicians be trained to include in the management of selected obese COPD patients, comprehensive sleep history, sleep hygiene and OSA screening because, in clinical practice, OSA is quite often underdiagnosed in these patients.
Synergic and Antagonistic Action of Active Principles on Chromium-Lead Antagonism - in vivo Experiments
Authors: Nicula Marioara , Pacala Nicolae , Stef Lavinia , Pet Ioan , Radulov Isidora , Iancu Tiberiu , Ahmadi Mirela , Dronca Dorel , Gherbon Adriana
Published: January 2020

Heavy metal pollution of the aquatic environment has become a major concern for the world. As natural water pollutants, heavy metals are among the most toxic due to their cumulative effect and the difficulty of being converted into insoluble compounds in the surface waters. Lead and its compounds are toxic to aquatic organisms, especially fish, even at low concentrations, being able to replace essential elements from the organism. Thus, we tested the concentration of chromium in tissues of Prussian carp�s fingerlings, exposed to chronic lead intoxication, following the synergic and antagonistic effects of some active principles from garlic and chlorella in various tissues. Our experiment was performed on 120 Prussian carps for 21-days as following: C group (without treatment), E1 group (75 ppm Pb into water as Pb(NO3)2 x �H2O), E2 group (75 ppm Pb into water+2% freeze dried garlic in feed), E3 group (75 ppm Pb into water + 2% freeze-dried chlorella in feed). At the end of the experimental period, tissue samples (gills, muscle, heart, skin and scales, intestine, liver, brain, gonads, and kidney) were sampled after anaesthesia. Atomic Absorption Spectrometry was used to determination of chromium concentrations in tissues. Our results revealed that freeze-dried garlic presented antagonistic effect between administrated lead and tested chromium concentration, while the chlorella showed antagonistic and synergic action, depending on the organ tissue that we had analysed.
Preparation and Characterization of Fe3O4 Magnetic Nanofluid in Vegetable Oil
Authors: Malaeru Teodora , Patroi Eros Alexandru , Marinescu Virgil , Oprea Ovidiu , Patroi Delia , Morari Cristian , Manta Eugen , Georgescu Gabriela
Published: January 2020

This paper reports the synthesis of Fe3O4 nanoparticles with a hydrophobic surface functionalized with oleic acid through a simple and efficient route in air atmosphere and by co-precipitation. The hydrophobic surfactant agent was added in the magnetic crystal growth stage. Magnetic nanofluid was obtained by ultrasonic dispersion of magnetic nanoparticles in a carrier liquid � vegetable oil. The sample as powder has been characterized by X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR) spectroscopy, Transmission Electron Microscopy (TEM), and Vibrating Sample Magnetometry (VSM) at room temperature. The magnetic nanofluid in vegetal oil was investigated by determining the stability of the nanoparticles in the vegetable oil through UV-Vis spectrometry method, the magnetic properties through Vibrating Sample Magnetometry (VSM) method at room temperature, and thermal conductivity as function of magnetic nanoparticles volume concentration and of temperature.
Involvement of Adiponectin in Early Phase of Acute Myocardial Infarction with ST-Segment Elevation (STEMI)
Authors: Parepa Irinel Raluca , Stoian Anca Pantea , Radulescu Anca Mihaela , Tica Irina , Mazilu Laura , Stanculeanu Dana Lucia , Suceveanu Adrian Paul , Serafinceanu Cristian , Suceveanu Andra-Iulia
Published: January 2020

Adiponectin is secreted by fatty tissue; it has a peptide biochemical structure and among other roles, it seems to inhibit endothelial inflammation. C-reactive protein has an essential role in host defense. Troponin is a protein that is part of cardiac and skeletal muscle contraction. Myocardial infarction is an acute event defined as myocardial cell necrosis, caused by sudden and sustained ischemia. The purpose of our search work was to analyze the connection between various biomarkers over the early phase of acute STEMI: adiponectin, high sensitive-C reactive protein (hs-CRP), high sensitive-Troponin T (hs-Troponin T), triglycerides, total -, LDL- and HDL-cholesterol. Our study included two groups of patients - one group of 30 patients diagnosed with STEMI in the first 12 h after onset, and the second group of 30 patients with unstable angina pectoris, normal hs-Troponin T, and normal findings at coronary angiography computed tomography (CT). Subjects in the STEMI-arm had a higher serum level of hs-CRP, hs-Troponin T, total cholesterol, LDL cholesterol, triglycerides, and decreased levels of HDL-cholesterol and adiponectin than those in the angina-arm. We identified diminished adiponectin plasma concentrations during the first hours of STEMI evolution. We also found out a directly proportional ratio among adiponectin and HDL-cholesterol and an inverse report between this hormone and all other studied biomarkers. Our results may support the anti-inflammatory and anti-atherogenic features of adiponectin.
Determination of alpha-Tocopherol Acetate in an Anti-Aging Cosmetic Cream by Gas Chromatography
Authors: Juncan Anca Maria , Rus Luca Liviu , Gligor Felicia Gabriela , Morgovan Claudiu
Published: January 2020

A gas chromatographic method was applied by using the GC-FID tehnique for the determination of a-tocopherol acetate in an anti-aging properly developed cosmetic formulation. A simple methanol:acetonitrile organic solvent mixture (50:50v/v) was required for sample preparation and the separation of the studied compound was carried out in specific chromatographic conditions. The analysis was carried out in proper developed anti-aging cream sample and satisfactory results were obtained for the recovery of the studied compound.
The Efficiency of Recombined Growth Hormone Therapy in Idiopathic Short Stature
Authors: Demetrian Alin , Preda Smaranda Adelina , Cristea Oana Mariana , Dragomirescu Carmen , Vladu Ionela Mihaela
Published: January 2020

Idiopathic short stature (ISS) deficiency reflects a major public health issue. In Romania the incidence is 1/3000 - 6000 births, with an increased prevalence in boys. ISS is the condition where the height of a subject is more than -2.5 DS below the height of the population for the population in which it is included, below the mean height for age and sex, but without any nutritional, systemic or chromosomal abnormalities. Significant for children with ISS is that weight is normal at birth and growth hormone levels are normal. This study shows the evolution of the height to normal values specific to the biological age, reaching the normal stature, according to auxological parameters, after growth hormone therapy.
Aesthetic Rehabilitation of the Teeth using Single Fixed Prostheses
Authors: Caraiane Aureliana , Toma Vasilica , Raftu Gheorghe , Debita Mihaela , Dimofte Alina-Ramona , Iordache Cristina
Published: January 2020

Dental aesthetics has always been an integral part of practical dentistry despite the fact that only in the last decade it has benefited from an objective critical analysis. Initially, aesthetics is regarded as an art - synonym for subjective, romantic and sentimental sensations. At a time when the basic aesthetic principles were based on Greek and Roman mathematics, the painters studied the aesthetics in order to create the painting, reflected in the depths of our soul. One can have an everlasting discussion about the two facets of dental-scientific and subjective aesthetics. It can be difficult to differentiate dental aesthetics from distinct units because all components are closely interrelated and interdependent. Complete and complex oro-dental treatments should be performed in such a way as to give back the patient both the masticatory functional skills, the feeling of comfort and the aesthetically lost aspect. The general trend in dental medicine focuses on replacing materials that, while meetingfunctional requirements, are not aesthetically pleasing. Thus, new generations of composite materials or integral ceramics take precedence over metal alloys used in dental treatments, from amalgam alloys to metal prosthetic restorations, including even gold ones. The database includes selection, examination and prosthetic resolution of 38 cases in the University of Galati University Prosthetic Clinic in the period 2016-2018. The possibility of creating unidirectional prostheses is a plus in the realization of true to nature works. Prosthetic variants, like dental faces, through which changes in shape, colour and even slight position can be made, with minimal invasiveness, or even non-invasive in the case of no-prep facets are a real advantage to aesthetics. From a biological point of view, the IPS e.max Press ceramic whole system is superior in that it is chemically inert, has a dental-like hardness, therefore it does not produce abrasion, the lack of metal avoids gingival changes colour, galvanic phenomena, and also a possibility of treatment for allergic persons in different components of the metal structure; the biocompatibility of these materials is clearly superior.
Analytical Characterisation of Original Emulsion for Cosmetic Use
Authors: Stanciu Gabriela , Oancea Adina-Ioana , Oancea Elena , Chirila Elisabeta
Published: January 2020

The aim of the paper is to characterize an original emulsion containing a mixture of plant macerates and essences. Next the wild and/or garden plants, namely Abies sp. (leaves), Crataegus monogyna (flowers), Hypericum perforatum (flowers), Lavandula angustifolia (flowers), Lavandula officinalis (flowers), Lilium sp. (flowers), Melissa officinalis (flowers), Mentha silvestris (leaves and flowers), Mentha piperita (leaves and flowers), Origanum vulgare (leaf blooms and flowers), Pinus silvestris (buds), Populus nigra (buds) and Thymus serpillum (flowers) have been processed to prepare the studied emulsion. Some of the emulsion ingredients as the essential oils of single plant and plant mixture, or the lily flowers macerate together with the final product have been analyzed. The measurements of physical and chemical properties (refractive index, density, pH, oxidation-reduction potential, acidity index, peroxide index and iodine index) led to interesting results that could explain the curative effects on skin. The beneficial effects of new emulsion are due to the bioactive compounds that penetrate deep into the tissue and ensure regeneration. The obtained results confirm our previous findings concerning the opportunity of measurements of oxidation/reduction potentials for cosmetic mixtures regarding the antioxidant activity description.
Clinical and Stent-related Risk Factors for Recurrent Angina After Successful Percutaneous Coronary Intervention
Authors: Dinesch Violeta , Dinesch Mihail , Buruian Mircea
Published: January 2020

We evaluated the clinical and stent-related risk factors for recurrent angina (RA) symptoms after percutaneous coronary intervention (PCI), as identifying and treating them could improve patient outcomes. We retrospectively analysed patients readmitted at our clinic after successful PCI; 147 (81.66%) patients were hospitalised for RA. Advanced age was associated with RA symptoms. Drug-eluting stents used at the index PCI, especially in small coronary arteries, seemed protective against RA symptoms. In-stent restenosis, which was associated with RA, was more frequent in bare-metal stents than in drug-eluting stents. Further studies are needed to identify other potential risk factors for RA and to determine how to positively influence the evolution of known risk factors.
Intraoperative Anaphylactic Shock Following Cefuroxime-Axetil Routine Test Case report and literature review
Authors: Tiglis Mirela , Mester Andreea , Hurmuzache Tudor , Diaconu Camelia Cristina , Dragomirescu Razvan Ion Florin , Oprea Loredana Mihaela , Bratu Ovidiu Gabriel , Neagu Tiberiu Paul , Socea Bogdan , Lascar Ioan , Grintescu Ioana Marina
Published: January 2020

Approximately 72% of patients with anaphylaxis present cardio-vascular manifestations, with only few reported cases of cardiogenic shock and cardiac arrest. Cephalosporins are the most used antibiotics for prophylaxis in the perioperative period with a prevalence of allergic reactions between 1-3%. Cefuroxime, a second-generation semisynthetic cephalosporin, presents relatively rare anaphylactic reactions (0.015%). Kounis syndrome is characterized by appearance of acute coronary syndrome in the presence of platelets, basophils or mast cells activation, due to an allergic reaction, hypersensitivity, anaphylactic reaction or shock. We report a rare case of a 53-year-old female patient with intraoperative anaphylactic shock following Cefuroxime-axetil routine test, complicated with Kounis syndrome and finally with cardiac arrest.
Non-Contrast Computed Tomography and the Impact of Stone Density to Choose Minimal Invasive Treatment
Authors: Scarneciu Ioan , Banuta Alexandru , Maxim Laurian , Giordano Salvatore , Marcu Dragos Radu , Bohiltea Roxana , Ionita-Radu Florentina , Turcu Flavia Liliana , Socea Bogdan , Isvoranu Gheorghita , Scarneciu Camelia Cornelia
Published: January 2020

Reno-ureteral lithiasis is a common pathology especially in socio-economically developed countries and may pose serious problems with renal function impairment. Urology is currently one of the surgical branches that benefit from a wide range of therapeutic options in reno-ureteral lithiasis, that revolutionized the criteria and indications of the lithiasis pathology, increasing the success rate and decreasing the number of days of hospitalization but which cannot provide satisfactory results if not complemented by imaging examinations. Non-contrast computer tomography is a key element in determining the best method of treatment by measuring the density of stones and increasing the stone-free rate of patients. Measurement of the stones density is done by Hounsfield units (HU), and patients who have had a [500 HU density have pleaded in over 90% for the uric acid composition. We included in our study a batch of 364 patients with reno-ureteral lithiasis and the treatment method was chosen based on the density of the stones: 64.83% of the patients with a density between 200-700 HU performed semi-rigid ureteroscopy and ballistic lithotripsy, 3.57% of patients with density between 700-1000 HU benefited from flexible ureteroscopy and laser lithotripsy, 17.58% of patients with density between 400-700HU performed ESWL and 13.73% with density]1000 HU have benefited from PCNL.
The Effects of Tumor Necrosis Factor Inhibitors in a Particular Association of Psoriatic Arthritis and Behcet Disease
Authors: Musetescu Anca Emanuela , Florescu Alesandra , Bumbea Ana-Maria , Florescu Lucian Mihai , Ciurea Paulina Lucia , Bondari Andrei , Florescu Dan Nicolae , Bondari Simona
Published: January 2020

The current case report presents a patient diagnosed with Behcet disease in concurrence with psoriatic arthritis, leading to a complex treatment, difficult management and challenging approach of both rheumatic disorders. After treatment with synthetic disease-modifying drugs and three different TNF inhibitors, the patient developed pulmonary tuberculosis, followed by tuberculosis spondylodiscitis, even after proper anti-tuberculosis therapy.
Study on the Correlation between Salivary pH and the Use of Mouthrinses in Young Adults
Authors: Bobu Livia , Vasluianu Roxana , Baciu Elena Raluca , Bulancea Bogdan , Murariu Alice
Published: January 2020

The aim of the present study was to assess the correlation between salivary (flow rate, pH) and clinical (GI, PI) parameters and the use of two common mouthrinses in young adults. A total of ninety subjects were randomly assigned to three groups, i.e. group A -Listerine�, group B -0.05% sodium fluoride, and group C -distilled water. After 6 weeks of using the corresponding mouthrinses twice a day, the results showed that Listerine� produced the highest increase of the salivary pH (7.58�0.043) and flow rate (0.82�0.280) and the highest decrease of the GI (0.79�0.177) and PI (1.30�0.375). Significant correlations (p[0.05) were found between the use of mouthrinses and the salivary and clinical parameters examined.
Influence of Synthesis Parameters of FeNi3 Alloy Nanoparticles Obtained by Chemical Reduction Method in Aqueous Solution
Authors: Malaeru Teodora , Patroi Eros Alexandru , Patroi Delia , Manta Eugen , Marinescu Virgil , Georgescu Gabriela
Published: January 2020

This paper reports the synthesis of FeNi3 alloy nanoparticles by chemical reduction of the Fe2+ and Ni2+ ions, from the corresponding chlorides, with hydrazine (N2H4�H2O) as a reducing agent in aqueous solution at room temperature by modifying the molar ratio of the ions Fe2+: Ni2+, reaction time, with and without amine-type growth promoter, and reducing both, with or without ultrasonic aid. The FeNi3 alloy nanoparticles have been investigated by XRD, EDS spectrum analysis, SEM and VSM. When the molar ratio of Fe2+ and Ni2+ is equal to 1:3, reducing both, with or without ultrasonic aid, Fe2+ and Ni2+ were completely reduced into Fe and Ni, resulting FeNi3 alloy with a face-centered cubic (fcc) crystal structure. EDS analysis supported the presence of metal ions in atomic weight corresponding to the stoichiometric ratio of initial reaction. SEM analysis showed that nanoparticles of FeNi3 alloy have a spherical structural morphology. Hysteresis loop show a ferromagnetic behaviour of the FeNi3 alloy nanoparticles at room temperature.
The Prevalence of Vitamin D Defficiency and its Obstetrical Effects. A prospective study on Romanian patients
Authors: Bohiltea Roxana Elena , Zugravu Corina-Aurelia , Neacsu Adrian , Navolan Dan , Berceanu Costin , Nemescu Dragos , Bodean Oana , Turcan Natalia , Baros Alexandru , Cirstoiu Monica Mihaela
Published: January 2020

The birth, growth, development, reproduction and senescence under physiological conditions can be achieved without diminishing the role of other important aspects that influence them, only with the support of an optimal diet that is a fundamental requirement nowadays, considering that the health and the nutritional status are in a permanent interdependence. The effects of inadequate nutrition reflect on the expression of genes, influencing the development of certain diseases in childhood and adulthood. Knowing the phases of the gestation period in which the need of certain nutrients is increased, and their absence has the most serious impact on fetal growth and development, allows for the adoption in due time of concrete preventive rules. Disorders associated with lipid malabsorption, such as celiac disease, Crohn�s disease, pancreatic insufficiency, cystic fibrosis and cholestatic disease, are associated with low serum levels of 5-hydroxyvitamin D. Vitamin D deficiency in the newborn can express as deficient skeletal homeostasis, congenital rickets and fractures in the early days of life. A low level of vitamin D during pregnancy seems to increase the risk of preeclampsia, intrauterine growth restriction and gestational diabetes, and in the longer term it seems to affect the bone, immune system and general status. The prevalence of hypovitaminosis D is increasing globally, and the effects on pregnancy and neonatal outcome of the vitamin D deficiency and supplementation are a topical issue, which is currently under investigation.
Accuracy of Imaging Investigations in Pancreatic Cancer Diagnosis
Authors: Sas Lorena , Taisescu Oana , Artene Stefan-Alexandru , Dricu Anica , Sas Theodor , Gindrovel Dumitra , Taisescu Citto Iulian
Published: January 2020

Pancreatic adenocarcinomas are considered one of the most complicated cancers in terms of treatment options and patient management. Regarding the diagnosis of pancreatic cancers, imaging techniques still play the central role with multiple options such as Computer Tomography (CT), Ultrasound (US), or Endoscopic Ultrasound (EUS) being available. The study was conducted at the Emergency County Hospital of Craiova, at the Radiology and Medical Imaging Department, the Imaging Compartment of the Research Center of Gastroenterology and Hepatology Research Center, on 170 patients suffering from pancreatic cancer, mostly adenocarcinomas. The neoplastic lesions were described using either US, CT or EUS techniques. The location of the tumor was assessed suing US and CT examination for all 170 patients in the study. There was a statistically significant correlation ([ 0.0001) between US and CT examination in terms of accuracy, with both techniques proving to be highly reliable. For measuring tumor size, 31 patients were evaluated using CT and EUS techniques. EUS proved to be more accurate in comparison to CT examination, with 9 (27%) of the total 31 patients having their tumor size underestimated by CT examination. There are no notable differences between the US evaluation of the tumor location and the actual location identified at the CT scan. As for tumor size, EUS showed greater reliability in evaluating tumor size in comparison to CT examination.
Influence of Formation and Morphometry of the Inferior Vena Cava in the Use of Antithrombotic Devices
Authors: Bordei Petru , Sapte Elena , Burcut Corina , Hainarosie Razvan , Jecan Radu Cristian , Popa Cristian Constantin , Ardeleanu Valeriu
Published: January 2020

The formation level of the inferior vena cava in the vertebral column was found to be at the level of L3 -L4 and L5 - S1, with differences between genders. The total length of the inferior vena cava ranged between 187.10 and 278.3 mm. Interiliac angle measured 48.40 and 85.80o. The length of the IVC from its formation point up to the termination of the right renal vein in the IVC ranged between 78.50 and 135.0mm, and the length of the IVC from its formation point to the termination of the left renal vein into the IVC ranged between 89.80 and 119.0mm. The length of the IVC from its formation up to the termination of the hepatic veins ranged between 197.20 and 263.70mm. The diameter of IVC at the point of its formation ranged between 18.0 and 26.20 mm, at the level of the right infrarenal level ranged between 20.10 and 28.70 mm, in 78.08% of the cases. In female cases, the diameter ranged between 18.06 and 25.69 mm, the diameter of the IVC at the level of the right suprarenal ranged between 19.82 and 31.09mm, the diameter at the level of the left infrarenal ranged between 18.59 and 32.49mm, at the level of the left suprarenal vein ranged between 19.10 and 33,80 mm, the diameter at the intrahepatic level ranged between 20.30 and 33.40mm, and the diameter of the IVC at the suprahepatic level ranged between 23.10 and 37.0mm.
Impact of Therapy with L-Thyroxine on the Evolution of Arterial and Aortic Stiffness in Female Patients with Overt and Subclinical Hypothyroidism
Authors: Tudoran Mariana , Tudoran Cristina , Vlad Mihaela , Balas Melania , Awwad Ahmed Abu , Pop Gheorghe Nicusor
Published: January 2020

The objective of this study is to highlight the impact of therapy with L-thyroxine on the altered arterial stiffness (AS) and reduced aortic distensibility (AoD), as well as on the left ventricular (LV) hypertrophy (LVH) and diastolic dysfunction (DD) in hypothyroid female patients.
Study of Some Psychoactive Drugs and Their Role in Increasing the Risk of Suicide
Authors: Brincoveanu Ana Maria , Suciu Oana , Hogea Lavinia Maria , Vlaicu Brigitha , Fira Mladinescu Corneluta , Bagiu Radu , Bagiu Iulia , Tuta Sas Ioana , Bacean Miloicov Codruta , Nussbaum Laura Alexandra , Chiriac Daniela Veronica , Poroch Vladimir , Putnoky Salomeia
Published: January 2020

The study aims to evaluate some predictors in the statement of suicidal thoughts in the last year by students from Timisoara universities, Romania. The student population consisted of 2536 young people aged 18-29, with an average age of 21.06 years and a standard deviation of 1.529 years, 64.5% girls and 35.5% boys. It was conducted a transversal population survey. In the logarithmic model of predictors in the context of social and psychoactive drugs use in students regarding the likelihood of suicidal thoughts in the last year, we have identified predictors with OR between 1.5-2, poorly significant: dissatisfaction with the relationship with parents (OR = 1.782), drug use frequency (OR = 1.697), dissatisfaction with the relationship with current friends (OR = 1.531).
Predictive Value of Several Echo Parameters for Cardiovascular Events in Hemodialysis Patients with Mid-range and Preserved Ejection Fraction Heart Failure
Authors: Ivan Vlad Sabin , Albulescu Nicolae , Albulescu Iuliana Roxana , Apostol Adrian , Buzas Roxana , Schiller Adalbert , Timar Romulus , Lighezan Daniel , Ivan Mihaela Viviana
Published: January 2020

Patients with end stage renal disease (ESRD) on hemodialysis (HD) are predisposed to higher rates of major cardiovascular events, through several well-known pathophysiological mechanisms. The rates of all-cause mortality are 6 to 10fold greater for these patients compared with general population. Furthermore, diabetes mellitus, history of cardiovascular disease, dialysis duration, and residual diuresis are factors related to cardiovascular events in hemodialysis. Whilst structural and functional echocardiographic abnormalities in dialyzed patients have been the surrogate for several survival studies, the predictive value of these echo parameters, are not clearly established in this field .In dialysis patients, it is still unclear which echo parameter is the best in determining cardiovascular outcome. The purpose of our study was to investigate the role of Doppler Echocardiography and Tissue Doppler Imaging (TDI) abnormalities, in providing predictive parameters for this particular population. The survival rates were analyzed by Kaplan�Meier curves and cardiac events predictors by Cox�s proportional-hazards model. We found correlations between several echo measurements and cardiovascular events, especially diastolic dysfunction and impaired left ventricular parameters. We strongly recommend the use of these echocardiographic parameters in early detection of patients at high risk in order to reduce morbidity and mortality.
The Impact of Ulipristal Acetate (UPA) versus Dienogest on Pain Related to Endometriomas Evaluated with Visual Analogue Scale (VAS)
Authors: Sima Romina Marina , Albu Dragos , Cringu Ionescu Antoniu , Dimitriu Mihai , Popescu Mihai , Tomescu Dana-Rodica , Chicea Radu , Ceausu Iuliana , Iordache Ioan-Iulian , Poenaru Mircea-Octavian , Matei Alexandra , Calin Alina , Ples Liana
Published: January 2020

Visual analogue scale (VAS) is a psychometric scale applied to measure subjective characteristics. The purpose of our study was to evaluate the efficiency of Ulipristal acetate (UPA) compared with Dienogest for endometriomas related pain using VAS. We performed a randomized study on women with symptomatic endometriomas. The study was realized between January 2016�December 2018. The patients were randomized in two groups: Group A- that received UPA in doses of 5 mg daily for 12�13 weeks and Group B that received 2 mg Dienogest for 12�13 weeks. Each group received de VAS (Visual Analogue Scale) questionnaire before and after treatment. 70 women wereincluded in the study with 35 patients for each group. The age the mean age was 30.20 years. For Numeric Rating Scale before treatment in the group with UPA the median value was 6 (CI= 5.26, 6.51) and for group B the median was 5 (CI= 5.13, 5.66). After treatment for group A the median value was 4 (CI= 3.58, 4.29) and for group B the median value 4 (CI= 4.23, 4.6). For FRS before treatment in the group with UPA median value was 6 (CI= 5.87, 6.58) and for the group B median was 6 (CI= 6.16, 6.57). After treatment for group A the median value was 4 (CI= 4.12, 4.73) and for group B the median value 5 (CI= 4.9, 5.06). The pain significantly improved for group A. (p[ 0.05)
VAS represent a good method to evaluate the quality of pain for patients with endometriomas. The UPA and Dienogest treatment improve the VAS parameters with better results for UPA in the present study.
Silica Mesoporous Materials -an Efficient Sorbent for Wine Polyphenols Separation
Authors: Niculescu Violeta-Carolina , Miricioiu Marius , Geana Elisabeta-Irina , Ionete Roxana-Elena , Paun Nadia , Parvulescu Viorica
Published: January 2020

Highly ordered-pore SBA-15 was synthesized by co-condensation of tetraethylorthosilicate (TEOS) and 3-aminopropyltriethoxysilane (APTES) using an amphiphilic block copolymer as structure-directing agent. The BET, EDX, TGA-DSC and SEM analysis have been used for sorbent characterization. The adsorption properties of the calcined mesoporous silica SBA-15 material appears to be a consequence of the silanol groups presence that are active sites for adsorption, were evaluated in the clarification process of two types of red wines. The purpose of this study was the investigation of the total polyphenols content (reduction), the selectivity and stabilization for some compounds (phenolic acids, epicatechin, and catechin) and the chromatic characteristics of wine. HPLC chromatograms exhibit the retention of quercetin and trans-resveratrol, catechin, epicatechin, rutin, and phenolic acids. The decrease in the polyphenolic compounds content in red wines avoids the oxidative browning process without modification of wine color. Due to their beneficial to human health thanks to antioxidative, antiinflamatory, antiviral, cardioprotective, anticarcinogenic and antimutagenic properties the polyphenolic extract might prove interesting as pharmaconutrients or as dietary sources.
Study of the Health Effects of Red Beet Juice and Asorubine Food Dyes Used in Feeding and Watering of the Animals for Experience
Authors: Spataru Mihaela Claudia , Spataru Constantin , Solcan Carmen , Gradinaru Andrei Cristian , Donosa Raluca Elena , Hritcu Luminita Diana
Published: January 2020

The paper aims to investigate the health effects of red beet juice and asorubine food dyes used in mice feeding and watering, considering the common use of these food colorants as additives in human food. The investigations related to this study were performed over a 3-month period, using 30 male mice which were divided into three batches 10 mice each. The red beet juice has given to nutrients and waters a better organoleptic quality so, the weight gain of mice was registered. The same, the increase in weight of mice receiving asorubine was higher. The anatomo- and histo-pathological examinations of mice that received red beet juice do not indicate a clear toxicity of this dye. However, red beet juice should not be consumed daily and in large quantities. On the other hand, injuries induced by asorubine in liver and kidneys may be characteristic for toxicity. So, the use and consumption of asorubine as a food additive should be undertaken with caution; although this compound is more stable and does not oxidize over time, if possible replace it with natural dyes.
Investigations Concerning the Corrosion and Ultrasonic Cavitation Erosion of 316L Coatings Deposited HVOF on Nodular Cast Iron
Authors: Utu Ion-Dragos , Mitelea Ion , Bordeasu Ilare , Bena Traian
Published: January 2020

Stainless steel 316L coating was high velocity oxygen fuel (HVOF) sprayed onto the surface of nodular cast iron in order to improve its surface properties in terms of corrosion and cavitation resistance. The cavitation resistance and corrosion behaviour of the nodular cast iron was investigated before and after coating deposition. The morphology and microstructure of the samples was analysed by optical and scanning electron microscopy (SEM) and X-ray diffraction technique (XRD). The cavitation measurements were carried out on a standard vibrator device. They have been correlated with the microhardness and surface roughness measurements. The corrosion evaluation was made by electrochemical tests. The results showed enhanced values in cavitation resistance of approx. 2.7 times and a decreasing of the corrosion rate for the coated cast iron.
Variation of the T Lymphocytes According to Treatment in Breast Cancer
Authors: Zgura Anca , Gales Laurentia , Bratila Elvira , Mehedintu Claudia , Haineala Bogdan , Barac Ramona Ileana , Popa Amorin Remus , Buhas Camelia , Berceanu Costin , Andreescu Cristina Veronica , Anghel Rodica
Published: January 2020

Breast cancer is a multifaceted disease whose varied phenotype recapitulates only partially the biological complexity. At present, there are new approaches to the diagnosis and treatment of this form of cancer, but research should also focus on identifying and implementing other individual prognostic factors, factors that may lead to improved clinical decision making with regard to the patient, in order to establish an individualized treatment.
Considerations on the Hematologic Toxicity of the all IC-BFM 2002/2009 Therapeutic Protocol in Children with Acute Lymphoblastic Leukemia
Authors: Singer Cristina Elena , Dinescu Sorin Nicolae , Tudorascu Diana Rodica , Florescu Cristina , Dinescu Venera Cristina , Puiu Ileana , Calborean Veronica , Trasca Diana-Maria
Published: January 2020

Acute lymphoblastic leukemia (ALL) is the most frequent malign hematologic disease in children. We studied the hematologic toxicity caused by the cytostatic treatment which was administered to the children diagnosed with ALL, according to the ALL-IC-BFM 2002/2009 protocol. The study included a number of 15 children with ALL who were treated from 2008 to 2018 within the Oncopediatrics Department of the 2nd Pediatric Clinic of the Emergency County Hospital in Craiova. We decided upon the level of toxicity in blood values, taking into account the severity level (G), according to the Common Terminology Criteria for Adverse Events 2010 guideline and we calculated the mean value of the hemoglobin, leukocytes, neutrophils, and thrombocytes in the children with ALL, for every phase of the cytostatic treatment. The most severe toxicity (grade 4 of severity) was registered in neutrophils (7/15 patients), during the induction and re-induction periods; 4 of these patients had severe infections.
The Biochemical Relevance of Different Types of Oxidative Stress at the Ocular Level
Authors: Untu Razvan , Zamfir Carmen Lacramioara , Boanca Mihaela , Temneanu Raluca Oana , Zugun Florin Eloaie , Gales Cristina , Zamfir Alexandra-Simona , Strat Liliana , Folescu Roxana , Spataru Mihaela
Published: January 2020

The connection between oxidative stress and ocular injuries was highly debated, given the fact that, as a result of its particular structure, the eye may have different reactions when exposed to oxidative stress and visual activity and functionality are considerable compromised. Our experimental research focused on two types of induced oxidative stress on rats (disruption of circadian rhythm and diabetes mellitus) with impact on biochemical markers of oxidative stress. We have analysed the amplitude of significant antioxidant markers correlated with each individual type of antioxidant disorder. We observed alterations of stress biomarkers for all induced types of stress, but the most relevant are associated with diabetes mellitus and light exposure.