bluuebunny/crossref_metadata_2025 huggingface dataset:
PREVALENCE OF OBESITY AND ITS ASSOCIATED RISK FACTORS AMONG POST- BASIC RENAL CARE NURSING STUDENTS
Authors: Aung Myo Oo  , Al-abed Ali A. Al-abed  , Ohn MarLwin  , Sowmya Sham Kanneppady  , Sham Kishor Kanneppady
Published: May 2020

Obesity is one of the most common, yet among the most neglected, public health problems around the world and it is strongly associated with various non-communicable diseases such as hypertension, diabetes mellitus and coronary artery diseases. Health care personal especially nurses play an important role in educating public to have healthy lifestyle. However, there is an alarming rate of increase in number of obesity among nursing students as well as staff nurses. Therefore, the aim of this study was to determine the anthropometric measurements and its associated risks among post-basic renal care nursing students. Total of 142 post-basic renal care nursing students of five intakes were included in this cross-sectional study. The result of the study showed that 52% of participants were either overweight or obese although most of them were below 40 years of age. Majority of overweight or obese students were Malays and 78% of them being female. We also observed an association of systolic blood pressure (SBP), diastolic blood pressure (DBP) and waist circumference (WC)with increasing body mass index (BMI) (P= 0.001, P= 0.001 and P<0.001) which were statistically significant. Wald criterion estimated that WC and DBP were the most important predictors of BMI in present study. Our study concluded that obesity is prevalent among post-basic renal care nursing students. Urgent and appropriate action should be taken to deter the growing problem of obesity among nursing students and to avoid its subsequent complications in Malaysia.
INTERVENTION FOR OCCUPATIONAL FATIGUE AND SLEEPINESS AMONG HEALTHCARE WORKERS WORKING IN SHIFT: A SYSTEMATIC REVIEW
Authors: Mohd Fadhli Mohd Fauzi  , Hanizah Mohd Yusoff  , Mohd Rizal Abd Manaf  , Nazarudin Safian  , Muhammad Aklil Abd Rahim  , Mohd Faizal Madrim  , Azman Atil @ Azmi  , Ammar Amsyar Abdul Haddi  , Nur Adibah Mat Saruan
Published: May 2020

Healthcare workers typically work in shift to ensure smooth operation of healthcare industries around the clock. However, working in shift put them at risk of developing occupational fatigue and sleepiness during and after work, with multiple adverse effects to themselves and patients under their care. This review aims to identify available evidence-based intervention for fatigue and sleepiness among healthcare workers working in shift. We searched PubMed, Scopus and CENTRAL database from January 2013 to December 2017. Selection criteria included randomised controlled trials (RCTs) that investigated the effect of any interventions on fatigue and/or sleepiness among shift workers. Two authors independently screened titles and abstracts for relevant studies, extracted data, and assessed risk of bias. We included 8 relevant trials with 7 review-relevant participants. Given the methodological diversity of the included studies in terms of interventions and assessment tools, it is not possible to determine the effectiveness of these interventions to reduce occupational fatigue or sleepiness among healthcare workers working in shift. More good quality RCTs with comparable assessment tools is needed.
ARTIFICIAL INTELLIGENCE MODEL AS PREDICTOR FOR DENGUE OUTBREAKS
Authors: Dhesi Baha Raja  , Rainier Mallol  , Choo Yee Ting  , Fadzilah Kamaludin  , Rohani Ahmad  , Suzilah Ismail  , Vivek Jason Jayaraj  , Bala Murali Sundram
Published: May 2020

Dengue is an increasing threat in Malaysia, particularly in the more densely populated regions of the country. We present an Artificial Intelligence driven model in predicting Aedes outbreak, using predictors of weather variables and vector indices sourced from the Ministry of Health. Analysis and predictions to estimate Aedes populations were conducted, with its results being used to infer the possibility of dengue outbreaks at pre-determined localities around the Klang Valley, Malaysia. A Bayesian Network machine learning technique was employed, with the model being trained using predictor variables such as temperature, rainfall, date of onset and notification, and vector indices such as the Ae. albopictus count, Ae. aegypti count and larval count. The interfaces of the system were developed using the C# language for Server-side configuration and programming, and HTML, CSS and JavaScript for the Client Side programming. The model was then used to predict the population of Aedes at periods of 7, 14, and 30 days. Using the Bayesian Network technique utilising the above predictor variables we proposed a finalised model with predictive accuracy ranging from 79%-84%. This model was developed into a Graphical User Interface, which was purposed to assist and educate the general public of regions at risk of developing dengue outbreak. This remains a valuable case-study on the importance of public data in the context of combating a public health risk via the development of models for predicting outbreaks of dengue which will hopefully spur further sharing of data by all parties in combating public health threats.
DETERMINANT OF INDEPENDENT NATIONAL HEALTH INSURANCE OWNERSHIP IN INDONESIA
Authors: Bela Sari  , Haerawati Idris
Published: May 2020

The increasing of Independent National Health Insurance (NHI) membership is one of the indicators to achieve Universal Health Coverage. One of the challenges in extending such coverage is reaching it out to the informal sector. This study was aimed to analyze the determinants of Independent NHI ownership in Indonesia. This study used cross-sectional design, and the data were derived from Indonesian Family Live Survey (IFLS) 2014. 6,888 individuals aged ≥40 years were the sample of this study. To analyze the data, chi-square analysis and logistic regression were used. Based on the analysis, the proportion of respondent with Independent NHI is 16.6%. The ownership of independent NHI is influenced by the following factors: age 40-55 (PR=1.72 95%CI 1.41-2.09, p-value <0.001), Sumatra Island (PR=7.67 95%CI 5.55-10.59 p-value<0.001), very rich (PR = 2.26 95%CI 1.85-2.75 p-value <0.001), history of chronic disease (PR=1.33 95%CI 1.15-1.53 p-value<0.001), junior high school (PR = 2.21 95%CI 1.92-2.55 p-value<0.001), and urban (PR=1.79 95%CI 1.57-2.04 p-value <0.001). Region is the most dominant variable related to NHI ownership (p-value <0.001; Exp B= 7.03; 95% CI: 5.06-9.77). Independent NHI membership has not been maximal, yet. To increase this participation, the Social Security Administrator should approach each region with low NHI membership through promotion, socialization, and education about registration and the benefits of independent NHI.
The Effects of “Ceria” Chemotherapy Effect Management on the Life Quality Improvement of Children with Cancer
Authors: Lestari Siti , Asih Sri Hartini Mardi , Rusmiyati Rusmiyati
Published: May 2020

The prevalence of cancer in children is now increasing and followed by an increasing number of them who undergo chemotherapy. The effect of chemotherapy can reduce the children’s quality of life, hence it requires the contribution of nurses in improving health services to children with cancer. The purpose of the study was to analyze the effect management of “Ceria” chemotherapy : (C)egah Sariawan (preventing mucositis), Cegah (E)kstravasasi (preventing extravacation), (R)elaksasi (Progressive Muscle Relaxation to reduce fatigue), Cegah (I)nfeksi (preventing infection), (A)kupresur (acupressur to reduce nausea and vomiting) on the life quality of children with cancer. The method applied was experimental research using control group design with pretest posttest. The treatment group received intervention in the form of “Ceria” chemotherapy effect management from the researchers while the control group did not receive intervention treatment. The selection of research subjects for the treatment and control groups was done randomly. The children’s quality of life was measured before and after one week of intervention using PedsQL (Children's Quality of Life Inventory). The participants were 76 children (38 in the treatment  group and 38 in the control group). The results of the paired t test showed that there were significant mean differences of life quality before and after "Ceria" chemotherapy effects management on children with cancer (p = 0,0001; sig = 0.05), the highest life quality improvement was found on children who experienced progressive muscle relaxation. This study concludes that "Ceria" chemotherapy effect management  can improve the life quality of children with cancer. Therefore, the reseachers recommend nurses to apply “Ceria” chemotherapy effect management to improve the life quality of children with cancer.

 

Keywords: cancer, children, quality of life,  "Ceria" chemotherapy effect management
Benefits of Gotu Kola Leaf in Responding to Prevent The Form of Keloid in The Wound
Authors: Ago Muhammad Bagus Nitei , Adifa Diki Prawira
Published: May 2020

Keloids are a type of scar, which is the result of overgrowth of dense fibrous tissue that usually develops after healing a skin injury. Keloids occur due to prolonged inflammatory phases in the wound, resulting in increased fibroblast activity and continuous extracellular matrix formation. Gotu kola (Centella asiatica) leaves are effective in the treatment of wounds because they contain Triterpene components such as asiatic acid, madecassic acid, asiaticoside and madecassoside. The purpose of this literature review is to report the latest scientific findings on the role of gotu kola leaf content in preventing keloid formation by increasing fibroblast proliferation, increasing collagen synthesis and mucopolysaccharide acids, increasing intracellular fibronectin which then significantly increases the tensile strength of newly formed skin, inhibiting the phases of the formation of skin, inflammation of the keloid scar tissue. The method used in this article is article search through the NCBI database and Google Scholar. The year of publication of library resources is from 1999 to 2018 with 20 sources of literature. The theme collected was related to the Centella asiatica leaf content towards the wound phase to prevent keloid formation. The results of the synthesis of articles that have been found are gotu kola leaves can inhibit the formation of keloids in wounds.

 Keywords: gotu kola leaf, keloid, wound
Empowerment Strategies Through Coaching Interventions on Controlling Blood Sugar Levels the Elderly
Authors: Deswita Desi , Sefrizon Sefrizon , Mirawati Anita , Zulharmaswita Zulharmaswita , Afconneri Yudistira , Deharnita Deharnita , Hardoni Yulvi
Published: May 2020

The problem of elderly diabetes mellitus is complex and various interventions in the form of education have been carried out in controlling blood sugar levels but the results have not been optimal. Based on this, the researcher wants to know the effect of coaching intervention on controlling blood sugar levels of the elderly with diabetes in Indonesia. The quasi-experimental research design uses a treatment group. Sampling with consecutive sampling in which the intervention group was selected according to purpose, with 38 respondents. Independent t-test was used. The results obtained were significant differences in blood sugar levels after being given an intervention. Coaching interventions affect blood sugar levels of the elderly with diabetes. It was concluded that coaching interventions reduce blood sugar levels and provide opportunities for nurses to develop promotive and preventive efforts.

 Keywords: blood glucose levels, coaching intervention, elderly
Comparison of the Effect of 30° and 90° Sloping Position on Pressure Ulcer Incident on Stroke Patients
Authors: Sulistiyawati Arie , Cahyati Yanti
Published: May 2020

Pressure ulcer is a serious problem on stroke patients. The incidence of pressure ulcer has a negative impact on the physical, psychological, social, spiritual and economic burden of the family. One of the efforts to prevent the pressure ulcer is by providing a sleeping position with a 30 ° or 90 ° sloping position. Some hospitals still apply standard operational procedures with a 90 ° sloping position. Therefore, it is important to retest the prevention of pressure ulcer on stroke patients by using both sloping positions. This study aimed to compare the effect of 30 ° and 90 ° sloping position on the incidence of presssure ulcer on stroke patients at Hasan Sadikin Hospital Bandung. This quasi-experimental study involved 34 patients taken using purposive sampling technique which was then divided into groups of 30° and 90°  sloping positions (17 respondents each) with the matching was based on the Braden scale. Each group was repositioned every 2 hours and the incidence of pressure ulcer was evaluated every day for 72 hours. The results showed the incidence of pressure ulcer in the 30 ° sloping position group (5.88%) and 90° sloping position (41.18%). Statistical results using exact fisher showed a value of p = 0.039 (<0.05) which means that the incidence of pressure ulcer in the 30° sloping group was significantly less than the result of 90° sloping group. Based on the odds ratio of 11.200, it means that stroke patients who were given a 90° sloping position are at risk 11 times higher risk of pressure ulcer than in stroke patients who were given a 30° sloping position. The conclusion in this study is the incidence of fewer pressure ulcer in a 30 ° sloping position. The results and treatment protocol in this study can be used as one of the considerations in efforts to prevent pressure ulcer, especially in stroke patients.

Keywords: pressure ulcer, sloping position, stroke
Effect of Awareness Programme on Knowledge and Practice Regarding Birth Preparedness and Complication Readiness among Pregnant Women at Panchla Block, Howrah District
Authors: Sarkar Reba , Mani Smritikana
Published: May 2020

Birth preparedness and complication readiness or BP/ CR of pregnant women enable maternal and newborn survival. A quasi-experimental study was conducted to know the effect of awareness programme on knowledge and practice regarding BP/ CR among pregnant women in Panchla Block, Howrah District , West Bengal. Using the Mother and Child tracking system register 72 mothers with gestational age ≥ 36 weeks selected randomly from 12 sub-centers. Intervention was done through individual and group instructions and data were collected before and after intervention. The intervention through awareness programme to the pregnant women significantly raised the awareness level regarding BP/ CR, as the mean score was higher in the intervention group regarding birth preparedness ((17.1 after intervention versus 13.5 before intervention, t value 12.73 with 35 df ,  p<0.05) and complication readiness (13.8 after intervention versus 6.1 before intervention, t value 25.31 with 35 df , p<0.05). However, there is no significant improvement in mean score in the control group regarding birth preparedness. There is also, strong positive association between knowledge and practice (chi-square value 16.99 with 1 df and p<0.01).

Keyword: birth preparedness; complication readiness
Tindak Tutur “Request” Bahasa Inggris dalam Metode Role Play pada Mahasiswa Keperawatan
Authors: Priyastuti Maria Theresia
Published: May 2020

This research discusses the form of request and the strategy of request in English learning process using role play method. Objective: to describe the form of request and the strategy of request in English learning process using role play method. Method: descriptive qualitative with equal pragmatic methods using theory of Edmondson and House and Aijmer. The data were taken from role play conversation which contained speech act of request. The total sampling were used  20 groups when the nursing students did role play of giving health education. Data methods used listening and direct observation (participatory observation). Results: firstly, speech acts of assertive request in English learning that often used in role play conversations are "you can .., you must (have to), you should ... you had better" and tentative requests for speech acts are "can you ...?, And would you ...? ". Secondly The speech act of the request strategy asserts that it is possible for the hearer to do something and asks for permission to do something. Conclusions: the form and the strategy of requests are found in English learning process using role play method.
Peningkatan Pengetahuan dan Ketrampilan Bantuan Hidup Dasar pada Relawan Bencana
Authors: Suwaryo Putra Agina Widyaswara , Sari Zulfa Nur Ganda , Waladani Barkah
Published: May 2020

Korban henti jantung bisa dialami oleh siapapun dan kapanpun tanpa mengenal tempat kejadian. Salah satu faktor penyebab tingginnya kematian akibat henti jantung adalah terlambatnya pertolongan yang diberikan kepada korban segera setelah henti jantung. Mayoritas kasus henti jantung terjadi di pra-Rumah Sakit, mencapai 72%. Pengetahuan dan ketrampilan orang awam yang baik, meningkatkan angka kelangsungan hidup korban henti jantung sebelum mendapatkan penanganan lanjutan di Rumah Sakit. Relawan adalah orang atau tim yang paling sering menjumpai kejadian henti jantung dan korban tidak sadar ketika melakukan pencarian dan evakuasi korban. Tujuan dilakukan pengabdian masyarakat ini untuk meningkatkan pengetahuan dan ketrampilan relawan bencana. Proses pengabdian masyarakat ini terdiri dari edukasi dan praktik dengan materi bantuan hidup dasar. Perubahan kognitif sebelum dan sesudah edukasi dievaluasi menggunakan pertanyaan, dengan nilai rata-rata 35 menjadi 85. Peserta sangat antusias dalam mengikuti program edukasi bantuan hidup dasar. Pengabdian masyarakat dengan memberikan pengetahuan untuk meningkatkan ketrampilan relawan dalam memberikan pertolongan kepada korban tidak sadar. Tindak lanjut dari pengabdian masyarakat ini yaitu membuat tim relawan kolaborasi dengan medis untuk menangani kasus medis diluar Rumah Sakit

Kata kunci: bantuan hidup dasar; ketrampilan; pengetahuan; relawan bencana

IMPROVEMENT OF KNOWLEDGE AND SKILLS BASIC LIFE ASSISTANCE IN DISASTER VOLUNTEERS

ABSTRACT

Victims of cardiac arrest can be experienced by anyone and at any time without knowing the scene. One of the factors causing the high death due to cardiac arrest is the late help given to victims immediately after cardiac arrest. The majority of cases of cardiac arrest occur in pre-hospital, reaching 72%. Good knowledge and skills of lay people, increase the survival rate of victims of cardiac arrest before getting further treatment at the Hospital. Volunteers are the people or teams that most often encounter cardiac arrest and the victim is unconscious when searching and evacuating victims. The purpose of this community service is to increase the knowledge and skills of disaster volunteers. This community service process consists of education and practice with basic life support materials. Cognitive changes before and after education were evaluated using questions, with an average score of 35 to 85. Participants were very enthusiastic in participating in the basic life support education program. Community service by providing knowledge to improve volunteer skills in providing assistance to unconscious victims. Follow-up from this community service is to create a team of volunteers collaborating with the medical to handle medical cases outside the hospital.

Keywords: basic life support; disaster volunteer; knowledge; skills
Upaya Penguatan Mental Remaja Menghadapi Tantangan Zaman
Authors: PH Livana , Arisdiani Triana
Published: May 2020

Remaja merupakan individu berusia diatas 12 hingga 18 tahun. Masa remaja merupakan keadaan dimana konsep diri mulai terbentuk. Saat remaja mendapatkan pola asuh yang baik, lingkungan juga memberikan dukungan yang baik, maka remaja akan mempunyai konsep diri yang baik dan sesuai tahap perkembangannya, sebaliknya jika remaja mendapat pola asuh yang baik tapi lingkungan tidak memberikan dukungan yang baik maka remaja akan terbentuk konsep diri yang maladaptif, sehingga perlu dilakukan kegiatan berupa pendidikan kesehatan sebagai upaya menguatkan mental remaja dalam menghadapi tantangan zaman. Kegiatan ini dilaksanakan di SMP 2 Kendal Provinsi Jawa Tengah. Peserta dalam kegiatan ini adalah remaja di SMP 2 Kendal Provinsi Jawa Tengah yang berjumlah 48 remaja. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan remaja tentang perkembangan psikososial remaja dan bahaya narkoba sebagai penguatan mental remaja dalam  menghadapi tantangan zaman.

Kata kunci: penguatan mental;  remaja; tantangan zaman

 

AN EFFORT TO STRENGTHEN THE MENTALITY OF ADOLESCENTS IN FACING THE CHALLENGES OF THE TIMES

 ABSTRACT

Teenagers are individuals aged over 12 to 18 years. Adolescence is a condition where self-concept begins to form. When adolescents get good parenting, the environment also provides good support, so adolescents will have a good self-concept and appropriate stages of development, conversely if teenagers get good parenting but the environment does not provide good support, adolescents will form self-concept maladaptive, so it needs to be done in the form of health education as an effort to strengthen the mentality of adolescents in facing the challenges of the times. This activity was carried out in SMP 2 Kendal, Central Java Province. Participants in this activity were teenagers in SMP 2 Kendal, Central Java Province, amounting to 48 teenagers. The results of the activity showed an increase in adolescent knowledge in achieving adolescent psychosocial development as a mental strengthening of adolescents in facing the challenges of the times.

 Keywords: challenges of the times; mental reinforcement; teenager
Upaya Cara Mengatasi Disminore pada Remaja Putri
Authors: Wulandari Priharyanti , Kustriyani Menik
Published: May 2020

Dismenore muncul dengan berbagai jenis rasa nyeri,sepeti sakit yang teramat sangat, berdenyut, mual, nyeri seperti terbakar, atau sakit yang sangat menusuk.Dismenore bisa mendahului menstruasi dengan beberapa hari atau mungkin menyertainya, dan biasanya berkurang hingga akhir menstruasi. Dismenore bisa hidup berdampingan dengan kehilangan darah berlebihan berat, yang dikenal sebagai menorrhagia. Dalam keadaan yang normal, nyeri haid hanya membuat wanita merasa sakit dan tidak nyaman. Tetapi dalam keadaan yang parah, nyeri haid ini bisa membuat wanita tidak dapat bekerja dan harus beristirahat, nyeri sering bersamaan dengan rasa mual, sakit kepala, perasaan mau pingsan dan lekas marah..Tujuan kegiatan pengabdian masyarakat adalah mengetahui dan memahami tentang nyeri haid/disminore serta mengetahui dan memahami cara penanganan nyeri haid/disminore sehingga tidak mengganggu aktivitas selama pembelajaran di sekolah. Kegiatan dilaksanakan dua kali yaitu pertemuan pertama dengan memberikan penyuluhan tentang upaya cara mengatasi nyeri haid/disminore pada remaja putri. pertemuan kedua dengan demonstrasi cara mengatasi nyeri haid/disminore pada remaja putri. Hasil dari pengabdian menunjukkan bahwa ada peningkatan pengetahuan tentang nyeri haid/disminore serta mengetahui dan memahami cara penanganan nyeri haid/disminore.

Kata kunci: disminore; menstruasi; remaja putri

EFFORTS HOW TO OVERCOME DISMINORE IN PRINCESS ADOLESCENTS

ABSTRACT

Dysmenorrhea presents with various types of pain, such as extreme pain, throbbing, nausea, burning pain, or very sharp pain. Dysmenorrhea can precede menstruation by several days or may accompany it, and usually decreases until the end of menstruation. Dysmenorrhea can coexist with heavy excessive blood loss, known as menorrhagia. Under normal circumstances, menstrual pain only makes women feel sick and uncomfortable. But in severe conditions, menstrual pain can make a woman unable to work and must rest, pain often coincides with nausea, headaches, feelings of fainting and irritability. The purpose of community service activities is to know and understand menstrual pain/ disminore as well as knowing and understanding how to manage menstrual pain / disminore so that it does not interfere with activities during learning at school. Activities carried out twice, namely the first meeting by providing counseling about efforts to overcome menstrual pain/ disminore in princess adolescents. The second meeting with a demonstration of how to overcome menstrual pain/ disminore in princess adolescents. The results of devotion show that there is an increase in knowledge about menstrual pain/ disminore and knowing and understanding how to manage menstrual pain / disminore.

Keywords: disminore, menstruation, princess adolescents
Pemanfaatan Webinar dalam Bidang Keperawatan
Authors: Izza Syarifatul , Ningrum Bhekti Setya , Hariyati Rr. Tutik Sri
Published: May 2020

Sistem Informasi Kesehatan merupakan bagian yang penting bila dikaitkan dengan perkembangan dalam bidang kesehatan. Teknologi ini membuka peluang untuk berinteraksi dengan berbagai audiens untuk memberikan strategipendidikan baru dalam dunia keperawatan. Dengan penyebaran teknologi informasi dan kemajuan internet, pendidikan telah berubah dan pembelajaran onlinemenjadi berkembang pesat. Salah satunya adalah dengan pemanfaatan Webinar. Pelajaran berbasis webinar dengan pendidikan berkelanjutan melalui internet. Teknologi Webinar memiliki banyak manfaat di bidang pembelajaran online, memungkinkan untuk komunikasi realtime dan sinkron antara pembicara dan pendengar, mencakup jarak jauh untuk menjangkau audiens potensial, dan memungkinkan untuk mengarsipkan informasi berbasis web untuk digunakan nanti.Penelitian ini menggunakan perangkat penelitian PICO (Population, Intervention, Comparison, Outcome). Data diambil dari berbagai jurnal dari tahun 2010 sampai tahun 2019 tentang penielitian terkait pelaksanaan webinar pada perawat dan mahasiswa keperawatan. Penelitian ini menunjukan bahwa penggunaan Webinar dapat meningkatkan pengetahuan dan pengalaman perawat dalam proses pembelajaran.

 

Kata kunci: education, e-learning, literature review, penelitian, teknologi, webinar

 

WEBINAR UTILIZATION IN NURSING

 

                                                                ABSTRACT

Health Information System is an important part when it is associated with developments in the health sector. This technology opens opportunities to interact with various audiences to provide new educational strategies in the world of nursing. With the spread of information technology and the advancement of the internet, education has changed and online learning is developing rapidly. One way is to use Webinars. Webinar-based learning with continuing education via the internet. Webinar technology has many benefits in the field of online learning, allows for realtime and synchronous communication between speaker and listener, covers long distances to reach potential audiences, and makes it possible to archive web-based information for later use. This research uses the PICO research tool (Population, Intervention , Comparison, Outcome). Data was taken from various journals from 2010 to 2019 about research related to the implementation of webinars for nurses and nursing students. This research shows that the use of webinars can enhance nurses' knowledge and experience in the learning process.

 

Keywords: education, e-learning, literature review, research, technology, webinars
Pengaruh Pemberian Ekstrak Spirulina terhadap Antikanker
Authors: Putri Ayu Darma , Winata Icha Putri
Published: May 2020

Spirulina adalah cyanobacterium mikroskopik berfilamen, mengandung bahan yang bermanfaat bagi manusia antara lain alkaloid, flavonoid, steroid, saponin, dan senyawa aktif piperidinone, piperidine, hexadecanenitrile yang merupakan zat dengan aktivitas kemopreventif kanker yang poten. Zat ini mampu menginduksi apoptosis dengan menimbulkan fragmentasi DNA dan kondensasi nucleus dan juga memiliki kemampuan untuk menurunkan regulasi protein anti apoptosis dan meningkatkan regulasi protein proapoptosi. Tujuan literature review ini untuk mengetahui efek ekstrak spirulina terhadap antikanker. Penulisan ini menggunakan metode studi literature review. Sumber pustaka yang digunakan dalam penyusunan literature ini menggunakan buku pedoman terkait ilmu karsinogenesis dan manfaat ekstrak spirulina yang menggunakan penelitian-penelitian terbaru dengan proses pencarian model artikel database yang diterbitkan pada tahun 2005 sampai dengan tahun 2019. Berbagai penelitian eksperimental menunjukan bahwa spirulina memiliki efek antikanker. Ekstrak kasar Spirulina memiliki komponen aktif alkaloid, flavonoid, steroid, saponin, dan senyawa aktif piperidinone, piperidine, hexadecanenitrile merupakan komponen golongan senyawa alkaloid yang berperan dalam penghambatan kanker.

 

Kata kunci: spirulina, manusia, antikanker

 

THE EFFECTS OF SPIRULINA EXTRACT ON ANTICENCER

 

ABSTRACT

Spirulina is a microscopic filamentous cyanobacterium, containing substances that are beneficial to humans including alkaloid, flavonoids, steroids, saponins, and active compounds of piperidinone, piperidine, hexadecanenitrile which are substances with potent cancer chemopreventive activity. This substance is able to induce apoptosis by causing DNA fragmentation and nucleus condensation and also has the ability to decrease the regulation of anti-apoptotic proteins and increase the regulation of proapoptotic proteins. The purpose of this review literature is to determine the effect of spirulina extract on anticancer. Method: This writing uses the literature review study method. Literature sources used are manuals related to the science of carcinogenesis and the benefits of spirulina extract from recent studies with the process of searching for database articles published in 2005 to 2019. Results: Various experimental studies have shown that spirulina has an anticancer effect. Discussion: Spirulina crude extract has active components of alkaloids, flavonoids, steroids, saponins, and the active compounds piperidinone, piperidine, hexadecanenitrile are components of alkaloid compounds that play a role in cancer inhibition.

 

Keywords:  spirulina, anticancer
Metode Survei Kepadatan Jentik Nyamuk Aedes dengan Pengukuran Density Figure
Authors: Ramadhan Mega Rusdiyanti , Amanulloh Maharani , Krisdayanti Ester
Published: May 2020

Demam berdarah dengueadalahmerupakan suatu penyakit akut yang disebabkan oleh infeksi virus yang dibawa oleh nyamuk Aedesaegypti serta Aedes albopictus betina. Virus ini akan berkembang biak dalam sistim retikuloendotelial di dalam tubuh manusia. APC (AntigenPresenting Cells) adalah target utama virus dengue yang pada umumnya berupa monosit atau makrofag jaringan seperti sel Kupffer dari hepar dapat juga terkena. Virus bersirkulasi dalam darah perifer di dalam sel monosit/makrofag, sel limfosit B dan sel limfosit T. Viremia akan timbul pada saat menjelang gejala klinik, pada umumnya hingga 5-7 hari setelahnya. Literature review ini bertujuan untuk memberikan informasi tentang metode survei jentik nyamuk Aedes sp yang terdiri dari Container index, House index,  Breteu index untuk dapatmengetahui faktor resiko terjadinya penularan infeksi dengue yang dilakukan dengan melakukan observasi rumah.Metode yang digunakan dalam artikel ini adalah penelusuran artikel melalui database NCBI dan Google Scholar. Tahun penerbitan sumber pustaka adalah dari tahun 2005 sampai 2019 dengan 20 sumber pustaka.Tema dalam artikel yang dikumpulkan yaitu terkait metode survei jentik nyamuk Aedes sp yang diukur kepadatannya dengan Density figure. Hasil dari sintesa artikel yang telah ditemukan yaitu Semakin tinggi angka density figure, semakin berisiko dalam penularan penyakit infeksi dengue.

Kata kunci : demam berdarah dengue, container index, house index,  breteu index, density figure

 METHODS OF AEDES MOSQUITO DENSITY SURVEY WITH MEASUREMENT DENSITY FIGURE

ABSTRACT

Dengue hemorrhagic fever is an acute disease caused by a viral infection carried by female Aedes aegypti and female Aedes albopictus. This virus will multiply in the reticuloendothelial system in the human body. APC (AntigenPresenting Cells) are the main target of dengue viruses which are generally in the form of monocytes or tissue macrophages such as Kupffer cells from the liver can also be affected. The virus circulates in peripheral blood in monocyte / macrophage cells, B lymphocyte cells and T lymphocytes. Viremia will occur just before clinical symptoms, generally up to 5-7 days afterwards. This literature review aims to provide information about the Aedes sp mosquito larvae survey method which consists of a Container index, House index, and Breteu index to be able to determine the risk factors for dengue infection transmission by observing the house. The method used in this article is article search through the NCBI database and Google Scholar. The year of publication of library resources is from 2005 to 2019 with 20 library sources. The theme in the article collected is related to the Aedes sp mosquito larvae survey method whose density is measured with a Density figure. The results of the synthesis of articles that have been found are the higher the density figure, the more risky the transmission of dengue infection.

Keywords: dengue hemorrhagic fever, container index, house index,  breteu index, density figure
Penurunan Kadar Gula Darah Menggunakan Daun Kemangi
Authors: Wijaya Kadek Erwin , Widoyoko Abiyyi Pratama Husada
Published: May 2020

Diabetes di Indonesia dianggap sebagai masalah kesehatan utama dan telah menjadi perhatian sejak awal 1980-an. Diabetes adalah salah satu penyebab utama kematian di indonesia. Indonesia dinilai sebagai salah satu dari sepuluh negara teratas secara global dengan jumlah individu pengidap diabetes yang tinggi pada tahun 2013. Diperkirakan bahwa pola yang sama akan berlanjut kecuali intervensi untuk mencegah dan mengelola diabetes diterapkan. Metode yang digunakan pada penelitian ini adalah studi literature review. Sumber pustaka yang digunakan dalam penyusunan melibatkan 19 pustaka yang berasal dari 2 buku dan 17 jurnal internasional. Tahun penerbitan sumber pustaka yang digunakan dalam penulisan artikel adalah dari tahun 2010 sampai tahun 2018. Berbagai penelitian menunjukkan hasil yang cukup signifikan mengenai pengaruh daun kemangi terhadap penurunan kadar gula darah. Ergunol pada daun kemangi memiliki beberapa mekanisme sebagai antidiabetik seperti inhibisi aktivitas dari α-glucosidases, Inhibisi dari formasi AGE, mencegah perlekatan glukosa terhadap serum albumin dan meningkatkan konsentrasi dari enzim antioksidan. Asam ursolat dalam daun kemangi menstimulasi pengambilan glukosa melalui berbagai cara.

 Kata Kunci: daun kemangi, diabetes, eugenol, asam ursolat

 DECREASED BLOOD SUGAR LEVELS USING TULSI LEAVES

                                                                                        ABSTRACT

Diabetes in Indonesia is considered a major health problem and has been a concern since the early 1980s. Diabetes is one of the leading causes of death in Indonesia. Indonesia is rated as one of the top ten countries globally with a high number of individuals with diabetes in 2013. It is estimated that the same pattern will continue unless interventions to prevent and manage diabetes are implemented. The method used in this study is a literature review. Literature sources used in the preparation involved 18 libraries originating from books, national journals and international journals. The year of publication of library sources used in article writing is from 2010 to 2018. Various studies have shown significant results regarding the effect of tulsi leaves on reducing blood sugar levels. Eugenol on basil leaves has several antidiabetic mechanisms such as inhibitory activity of α-glucosidases, inhibition of AGE formation, prevent glucose attachment to serum albumin and increase concentration of antioxidant enzymes. Ursolic acid in tulsi leaves stimulates glucose uptake in various ways.

 Keyword: tulsi, diabetes, eugenol, ursolic acid
Potensi Saffron sebagai Antidiabates
Authors: Ismail Raden Ayu Jihan Fakhirah , Ningtyas Nurma Retno
Published: May 2020

Diabetes melitus adalah suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi  insulin, kerja insulin atau keduanya. Indonesia sebagai salah satu negara berkembang dengan jumlah penduduk yang tinggi memiliki risiko terjadinya masalah kesehatan yang lebih besar. Salah satu masalah kesehatan adalah meningkatnya epidemi diabetes melitus. Saffron, Crocus sativus, tanaman yang berasal dari genus Iridaceous, adalahtanaman yang dianggap sebagai salah satu tanaman herbal yang penting dalam bidang medis, kosmetik dan industri higienis lainnya.Review ini disusun dengan melakukan penulusuran sumber pustaka melalui database NCBI, Garuda, Sinta, dan Google Scholar. Hasil dari penelusuran 19 artikel yang ditemukan yaitu saffron memiliki kandungan crocin crocetin, procicin, safranalyang dapat menjadi kandidat antioksidan yang memiliki pengaruh signifikan terhadap kadar glukosa dalam darah.

 Kata kunci: Crocus sativus, diabetes melitus, glukosa, saffron

 POTENCY OF SAFFRON AS ANTIDIABETIC

 ABSTRACT

Diabetes mellitusis a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormal insulin secretion, insulin action or both. Indonesia as a developing country with a high population has a greater risk of health problems. One health problem is the increasing epidemic of diabetes mellitus. Saffron, Crocus sativus, a plant that belongs to the Iridaceous genus, is a plant that is considered one of the important herbal plants in the medical, cosmetic and other hygienic industries. This review was compiled by searching literature sources through NCBI, Garuda, Sprott, and Google Scholar databases. The results of 19 articles search found that saffron contains (crocin crocetin, procicin, safranal) which can be candidates for antioxidants that have a significant effect on glucose levels in the blood

 Keywords: crocus sativus, diabetes mellitus, glucose, saffron
Efektifitas Panax Ginseng terhadap Alopecia
Authors: Santi Karunia , Jaya Made Merta
Published: May 2020

Aspek fungsional rambut pada kepala tidak hanya untuk melindungi dari radiasi matahari dan paparan panas / dingin, tetapi juga untuk berkontribusi pada penampilan dan kepribadian seseorang. Kerontokan rambut progresif memiliki dampak kosmetik dan sosial. Rambut mengalami tiga tahap siklus rambut: fase anagen, catagen, dan telogen. Melalui kehilangan siklus dan pertumbuhan rambut baru, jumlah rambut tetap relatif konstan. Berbagai faktor, seperti hormon, status gizi, dan paparan radiasi, racun lingkungan, dan obat-obatan, dapat memengaruhi pertumbuhan rambut. Androgen adalah faktor terpenting yang menyebabkan alopesia androgenik. Bentuk lain dari kerontokan rambut termasuk kerontokan rambut imunogenik, yaitu alopecia areata. Meskipun sejumlah terapi, seperti finasteride dan minoxidil, adalah obat yang disetujui pencarian terhadap obat obatan alami atau tradisional tetap diperhitungkan salah satunya adalah ginseng. Sejumlah produk - produk sampo dan kondisioner memsukan bagian ginseng, telah menunjukkan pertumbuhan rambut - mempromosikan efek dalam sejumlah besar studi praklinis. Penelitian ini merupakan studi literature review.Tujuan dari tinjauan ini adalah melihat potensi ginseng dan metabolitnya pada pencegahan rambut rontok dan mekanisme yang mendasarinya.

 Kata kunci: alopecia, kerontokan rambut, ginseng

 EFFECTIVENESS OF PANAX GINSENG ON ALOPECIA

 ABSTRACT

The functional aspect of hair on the head is not only to protect from sun radiation and heat / cold exposure, but also to contribute to one's appearance and personality. Progressive hair loss has cosmetic and social effects. Hair experiences three stages of the hair cycle: anagen, catagen, and telogen phases. Through cycle loss and new hair growth, the amount of hair remains relatively constant. Various factors, such as hormones, nutritional status, and radiation exposure, environmental toxins, and medications, can affect hair growth. Androgens are the most important factor causing androgenic alopecia. Other forms of hair loss include immunogenic hair loss, namely alopecia areata. Although a number of therapies, such as finasteride and minoxidil, are drugs that are approved by the search for natural or traditional medicines, one of which is still considered ginseng. A number of shampoo and conditioner products, which have a part of ginseng, have shown hair growth - promoting effects in a large number of preclinical studies. This study used literatur review. The purpose of this review is to look at the potential of ginseng and its metabolites in the prevention of hair loss and the underlying mechanisms.

 Keywords:alopecia, hair loss, ginseng
Short and Improved Synthesis of Cytotoxic Homodimers with an Isoquinoline Structure
Authors: Meza Paulina , Vaccaro Silvana , Faundes Judith , Segura Rodrigo , Ibacache Juana Andrea
Published: May 2020

The syntheses of cytotoxic homodimers 5, 7-10 are described. Compounds 5, 7-10 were cleanly and efficiently obtained by microwave activation. A thorough study concerning oxidative reaction of diamines and isoquinolinequinones, under ultrasound (US) and microwave (MW) irradiation is presented. Under MW irradiation the yields are higher, the amount of precursor quinone used decreases substantially, the reaction time decreases considerably (from hours to minutes) in respect to previously reported methodology.
Effect of Silica Particle Size on the Physical and Mechanical Properties of Lightweight Ceramic Composites
Authors: Ismael Muna Noori , Hassan Hazim Faleh , Al-Lami Hadi Salman
Published: May 2020

Ceramics hold all traditional, scientific and engineering raw materials or fabricated products used in different applications especially that performed at high temperatures through high-tempers. The remarkable progress made recently in the advancement of technology has related a prerequisite for a seriously huge number of parts with controlled porosity. In ceramic manufacturing, acquiring a porous item of such parameters and at the same time demonstrating appropriate mechanical strength isn`t a simple issue. The powder-mixing system was utilized to fabricate kaolin-silica fired composites. The main purpose of the paper was to prepare ceramic bodies rich in pores with the goal that it will have a lightweight structure. Different wt.% of silica having distinctive two-particle sizes are blended with kaolin, and afterwards, they shaped by semi-dry pressing in a hardened steel mould under 3-ton loads and sintered at four various temperatures, 900, 1000, 1100 and 1200 �C. Evaluating of composite`s physical properties showed that a good level of porosity was obtained, and it was extended; especially in mixtures contain a coarse particle size. These results are enhanced by acceptable evident comes from good apparent solid density and good strength.
Yield Optimization Using Artificial Neural Networks in Biodiesel Production from Soybean Oil
Authors: Matei Danuta , Doicin Bogdan , Cursaru Diana , Ezeanu Dorin Stanica
Published: May 2020

Biodiesel plays an important role in reducing the dependency of petroleum fuels and reduce environmental pollution. Biodiesel has attracted attention as a renewable, non-toxic, and biodegradable fuel. In the past years, researchers have expanded their work to new methods of obtaining biodiesel. In this work, biodiesel production using soybean oil from the industry is described. Biodiesel was further analyzed and compared with the EN biodiesel specifications. The characterization of biodiesel was performed in order to obtain density, viscosity and flash point. Moreover, the study was focused in optimized the biodiesel yield, obtain from soybean oil using Artificial Neural Networks (ANN). The variable parameters were molar ratio between methanol and oil, reaction temperature and catalyst quantity. The paper concludes that the ANN can be successfully used to optimize the biodiesel yield.
Dimensional Changes in Co-Cr Alloys and Titanium Framework of Removable Partial Dentures Evaluation of the dimensions of the dental clasps
Authors: Gaman Simina , Bortun Cristina Maria , Scrieciu Monica , Mercut Veronica , Pascu Roxana Maria , Popescu Sanda Mihaela , Earar Kamel , Feier Ramona , Nicola Andreea Gabriela
Published: May 2020

Removable partial denture are prosthetic solutions that replace missing teeth of partially edentulous patients, ensuring stomatognathic system functionality with affordable costs.The purpose of this study is to analyze the dimensional variations caused by the execution errors, which can lead to premature deterioration of the removable partial dentures and to conclude what sizes are deficient and can lead to the deterioration of the prosthetic part. The material involved in the present study was represented by the metal framework of 181 removable partial dentures. Of the total of 181 removable prosthetic parts, 88 were maxillary prostheses and 93 were mandibular prostheses. Measurements were made at the retentive arms, opposing arms, minor connectors, rests and junction areas between the body of the clasps and the active arms and studied compared to the edentulous classes. The results are focused on dimensional changes of both the retentive arms and the opposing arms of the clasps, which are roughly modeled in the first 3 edentulous classes, with a significant difference from those achieved in Kennedy`s 4th class edentulous, where these segments of the clasps are much shorter. Regarding the size of the rests, although their thickness approximates the values indicated in the literature, they do not fit into the occlusal relief of the tooth. The length of the retentive arms varies according to the classes of edentulous, the clinical situation, but also the size and type of the tooth (premolars, molars) on which the clasp is applied. Regarding the opposing arm, the observed differences cannot be correlated with the objective criteria of their achievement because the attention is directed towards the realization of the retentive arm.
Impacts of Using Mineral Fertilization Combined with Sewage Sludge in the Amendment of Luvisol on Oat Crop. II. Influence on Metal Accumulation
Authors: Mihalache Mircea , Ilie Leonard , Scaeteanu Gina Vasile , Calin Catalina , Madjar Roxana Maria
Published: May 2020

The objective of the present paper was to investigate the effects of sewage sludge application on metals (Cu, Mn, Zn, Cd, Co, Pb) accumulation in oat (Avena sativa L.) grains, Somesan variety. It were used various doses of sewage sludge corresponding to equivalent doses of 0-600 kg N/ha associated or not with NPK mineral fertilization. The results evidenced that copper and zinc levels in oat grains increased significant with sewage sludge fertilization starting with a dose equivalent with 200 kg N/ha. Mineral fertilization led to significant decrease of copper content in comparison with sewage sludge treatments only. For manganese, fertilization with sewage sludge has produced a significant decrease, this trend being accentuated up to the equivalent dose of 300 kg N/ha. For cadmium, application of sewage sludge in an equivalent dose of 200 kg N/ha led to concentrations in oat grains higher than 1 mg Cd/kg (imposed limit for grains used for animal feed). This behavior is a consequence of high cadmium content of sewage sludge (of 7.2 times over maximum admitted limit). Cobalt contents of oat grains increased with sewage sludge doses, but the levels are between normal values and concordant with literature data. Application of sewage sludge in an equivalent doses of 500 and 600 kg N/ha generated a significant increase of lead content in oat grains, average values being 1.87 and 2.17 mg Pb/kg, respectively.