bluuebunny/crossref_metadata_2025 huggingface dataset:
АНАЛІЗ ЕФЕКТИВНОСТІ БРЕНДИНГУ НА ПІДПРИЄМСТВАХ ЛЕГКОЇ ПРОМИСЛОВОСТІ УКРАЇНИ
Authors: Зінорук Лідія
Published: March 2022

Досліджено теоретичні питання що стосуються розкриття сутності бренду, брендингу та їх ролі в сучасній економіці. Проаналізовано ефективність брендингу на підприємствах легкої промисловості. Встановлено, що політика брендингу дозволяє виділити товари підприємства серед загальної маси товарів у свідомості споживача. Тому успішна політика брендингу є чинником підвищення конкурентоспроможності підприємства. Впливаючи на вибір споживачів, бренд є важливим чинником формування кола лояльних споживачів, дозволяє компанії зміцнити свої позиції на ринку, забезпечує стабільність грошових потоків та збільшує вартість бізнесу. ефективний брендинг забезпечує формування кола лояльних споживачів, дозволяє компанії зміцнити свої позиції на ринку, забезпечити стабільність грошових потоків, збільшити вартість бізнесу, тобто є ефективним засобом здобуття конкурентних переваг компанії на ринку. Відповідно, питання аналізу політики брендингу є невід'ємною частиною проблеми підвищення конкурентоспроможності вітчизняних підприємств і стає сьогодні одним з найактуальніших Автором визначено поняття бренду та брендингу. Визначено 5 українських мас-маркет брендів. Охарактеризовано вітчизняний ринок легкої промисловості, розкрито його риси, сильні та слабкі сторони. Розкрито роль ефективності брендингу в умовах глобалізаційного світу. Встановлено взаємозв’язок бренду та конкурентоспроможності підприємства. Автором доведено, що сьогодні підприємства легкої промисловості орієнтовані на споживачів, жіночу робочу силу та джерела сировини, тому вони загалом поширені по всій Україні. Однак легка промисловість завжди відставала від потреб суспільства з точки зору асортименту, якості та обсягів виробництва, і в наш час у умовах глибокої кризи її частка у промисловому виробництві скоротилася. Визначено, що ефективний брендинг забезпечує формування кола лояльних споживачів, дозволяє компанії зміцнити свої позиції на ринку, забезпечити стабільність грошових потоків, збільшити вартість компанії, тобто є ефективним засобом отримання конкурентних переваг для компанії на ринку.
ОПТИМІЗАЦІЯ ДЕРЖАВНОГО ФІНАНСОВОГО КОНТРОЛЮ ЗА ЕФЕКТИВНІСТЮ ВИКОРИСТАННЯ КОШТІВ У БЮДЖЕТНИХ УСТАНОВАХ
Authors: Романів Євген , Цхай Діана
Published: March 2022

У статті проводиться аналіз основних принципів правового регулювання державного фінансового контролю відповідно до законодавства України, конкретизуються проблеми його правового регулювання та правоохоронної практики, визначаються перспективи вдосконалення законодавства у сфері, надаються пропозиції щодо вирішення виявлених проблем. Автор аналізує наукові позиції та з’ясовує суть та зміст терміна «державний фінансовий контроль». Водночас з’ясовано особливості державного фінансового контролю. Автор робить висновки про необхідність законодавчого закріплення принципів державного фінансового контролю. На основі аналізу чинного законодавства автор виявляє недоліки нормативно-правового регулювання у державному фінансовому контролі та визначає пріоритетні напрями їх удосконалення.
A. KOZLOV'S RECEPTION OF ANCIENT CHINESE PHILOSOPHY IDEAS IN UKRAINIAN PHILOSOPHY OF THE LATE 19TH – EARLY 20TH CENTURY
Authors: Ярмоліцька Наталія , Ган Катерина
Published: March 2022

The purpose of this article is to outline the receptions of keys Chinese philosophical ideas. The main focus is on the study of ancient Chinese philosophical culture, which was presented in the research of Ukrainian philosopher of the late XIX – early XX century A. Kozlov. This article provides an opportunity not only to get acquainted with ancient Chinese philosophy in the context of research in Ukrainian philosophy but also to deepen existing and gain new knowledge about the philosophical culture of ancient China. The authors conducted historiographical research of available sources, which contain studies of the foundations of ancient Chinese philosophy, reconstructed the social, cultural, and philosophical context of the historical era in which ancient Chinese philosophy was formed. The study of the heritage of Ukrainian philosophical thought in the period from the end of the XIX - beginning of the XX century is a priority for the authors of this study and will form the basis of further research in the field of Chinese-European studies in the field of philosophy. Such research contributes to the improvement of existing practices of intercultural communication, mutual understanding, and social partnership between Ukraine and China at the level of major social values, worldviews and language practices, literary discourse, and historical memory.
ПЕДАГОГІЧНА КОМПЕТЕНТНІСТЬ – ОДНА ЗІ СТОРІН ПРОФЕСІОНАЛІЗМУ МАЙБУТНЬОГО ПЕДАГОГА
Authors: Радченко Марія
Published: March 2022

Основне завдання сучасної освітньої політики полягає в тому, щоб вивести професійну освіту на якісно новий рівень, що забезпечує підвищення не тільки професіоналізму, а й професійно важливих якостей особистості. В сучасних умовах реформування системи освіти радикально змінюється статус педагога, викладача, його освітні функції, відповідно змінюються вимоги до його професійно-педагогічної компетентності, до підготовки спеціаліста та до рівня його професіоналізму. В роботі здійснено аналіз і досліджено сучасний стан проблеми розвитку професіоналізму майбутніх педагогів в процесі професійної підготовки; охарактеризована взаємозалежність понять «професіоналізм» та «професійна компетентність» майбутнього педагога.
МОВА ВОРОЖНЕЧІ ЯК СОЦІОКУЛЬТУРНИЙ ТА ЛІНГВІСТИЧНИЙ ФЕНОМЕН
Authors: Матюшенко Олена , Марченко Валентина
Published: March 2022

У статті розглядаються особливості функціонування мови ворожнечі як соціокультурного та лінгвістичного феномену. Проаналізовано існуючі дефініції терміну «hate speech» та «dangerous speech». Автори статті пропонують власне розуміння терміну «мови ворожнечі». Запропоновано власний підхід до диференціації цього явища. Проаналізовано приклади прояву мови ворожнечі у англійській лінгвокультурі, прокоментовано їх інтенсивність, а також їх реалізацію (комунікативні тактики, процедури та стратегії). Сформовано власне бачення вирішення проблеми мови ворожнечі у сучасній лінгвістиці, зокрема в дискурсі соціокультурного, лінгво прагматичного, когнітивного аспекту та в рамках прикладної лінгвістики.
Kahoot!, Plickers And Socrative: ICT resources to assess musical content in Primary Education
Authors:   Universidad de Castilla-La Mancha, López García Narciso José
Published: March 2022

Assessing musical competencies is a complicated process. However, the implementation of ICT in the classroom has facilitated this task, helping the Music education teacher to collect data in real time to describe the level of musical content of the students and information to fill in the required official documents. In this study, different evaluation strategies in music education are analyzed, as well as the main characteristics of three digital platforms, Kahoot!, Plickers and Socrative, whose main potential lies in the generation of gamified evaluation tests and evaluation and qualification reports of the students required by the educational administrations. The work method has been the analysis of information, which has served to make an exhaustive description of these platforms with the aim of providing the teachers information and tools that enable them to use and implement ICT in the evaluation of musical content of the Primary Education curriculum. Finally, the conclusions related to the benefits and limitations of these digital tools when applied in the Music classroom are presented.
Availability and technological knowledge of university mathematics teachers in the time of covid-19
Authors:   Instituto Tecnológico de Sonora, México, Acuña Michel Laura Lillian , Cuevas Salazar Omar ,   Instituto Tecnológico de Sonora, México, Angulo Armenta Joel
Published: March 2022

The purpose of the study was evaluating, in the face of the contingency caused by the Coronavirus Disease pandemic (COVID-19), the mathematics teachers knowledge and availability of technological tools for teaching remote university courses. The research adopted the quantitative approach and the design is non-experimental, transactional and descriptive. Eighty-one teachers participated and the survey consisted of 38 items with dichotomous answers, Likert scale and multiple selection. The questions were related to the remote modality, the availability of technology devices and services, and the use of technological tools. According to the results, the mathematics teachers of one south Sonora university have internet access and technological devices to distance teaching, they know or have used virtual classroom platforms and applications that allow communication with students. The areas of opportunity that were detected are the distance courses design, the online exams and didactic material preparation, as well as the implementation of tools that promote collaborative work.
TPACK: Innovation in the teaching of chemistry during the Covid-19 pandemic in high school students
Authors:   Universidad Autónoma del Estado de México, Becerril Morales Fernando , Mendoza González Brenda ,   Universidad Autónoma del Estado de México
Published: March 2022

Education with online tech tools during the pandemic caused by covid-19 was the principal alternative due the restrictions worldwide, and its insertion required models that made them more efficient. The aim of this research was to know the effectiveness of the TPACK model making use of ICT in the teaching-learning process of the subject Chemistry II in upper middle level, during the contingency. It was a quasi-experimental study with A-B-A design, involving 152 fourthsemester high school students from a public institution, distributed into four experimental groups in which an educational program was implemented. Three tests were designed and validated by expert judgement, with α = .91, .92 and .93, and were applied as a pre- and posttest. The educational program was developed in the TPACK model, using ICT. The data were analyzed through the student’s t-test and showed improved performance of the participating students after the intervention. An innovative design of instruction was generated with the TPACK model, which demonstrated its effectiveness for the insertion of technology for teaching that can be generalized to the instruction of other chemistry topics in high school.
The impact of an insecure asylum status on mental health of adult refugees in Germany
Authors: Boettcher Victoria Sophie , Neuner Frank
Published: March 2022

Background

Forcibly displaced people have a higher chance of developing post-traumatic stress disorder (PTSD) compared to people who have not experienced displacement. In addition to potentially traumatic events due to war, persecution, and flight, post-migration living stressors are an important influencing factor. Among these, an insecure asylum status is one of the main stressors with which forcibly displaced people must cope. The aim of this study was to investigate the additive effect of an insecure asylum status on PTSD symptomatology in refugees, over and above the influence of other pre- and peri-migration factors, in particular potentially traumatic event types reported and duration of stay in Germany.

Method

Two overlapping convenience samples of 177 and 65 adult refugees that were assessed at different timepoints were interviewed by means of face-to-face interviews. Interviews were conducted in either Arabic, Farsi, Kurmancî, English, or German with the assistance of interpreters where necessary. Besides residence status and potentially traumatic events experienced, mental distress was assessed via the Refugee Health Screener-15 (RHS-15; Study A) and the PTSD Checklist for DSM-5 (PCL-5; Study B).

Results

In both samples, an insecure asylum status explained a significant additional amount of variance of PTSD symptomatology, on top of traumatic events experienced and time since arrival in Germany.

Conclusion

Results suggest that refugees with an insecure asylum status are at higher risk for experiencing increased PTSD symptomatology. Policy changes of asylum procedure in receiving countries could have a positive impact on refugees’ mental health.
Public Domain Core Collection Faculty Guide
Authors: Wilson Sally , Forsythe Giulia , Ludbrook Ann , Murgu Cal , Lem Val , Thiessen Jennifer
Published: March 2022

This guide has been created to assist instructors in using the Public Domain Core Collection of texts and to provide some suggestions and examples of open assignments that can be created using these texts.
Taking risks the safe way: risk management and insurance practices of Ontario's Voluntary Sector
Authors: Unknown Author
Published: March 2022

Taking Risks the Safe Way was developed as a knowledge‐building tool and research reference for
nonprofit organizations across Ontario. The contents of this document will also guide the work of
government in supporting capacity‐building among voluntary and community organizations, and provide a
valuable resource for the insurance industry in serving the nonprofit sector.

Keywords: CVSS, Centre for Voluntary Sector Studies, Working Paper Series,TRSM, Ted Rogers School of Management

Citation
SARS-CoV-2 infection in the immediate post-transplant period: A report of five kidney transplant recipients
Authors:   Nephrology Department – Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal, Sousa Luís , Santos Afonso ,   Nephrology Department – Hospital Professor Fernando da Fonseca, Amadora, Portugal, Lima Anna ,   Nephrology Department – Hospital Professor Fernando da Fonseca, Amadora, Portugal, Nascimento Célia ,   Nephrology Department – Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal, Jorge Cristina ,   Nephrology Department – Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal, Bruges Margarida ,   Nephrology Department – Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal, Adragão Teresa ,   Nephrology Department – Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal, Weigert André ,   Nephrology Department – Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal
Published: March 2022

Introduction: The severe acute respiratory syndrome coronavirus 2 pandemic caused a negative impact on transplantation worldwide. One of the complexities is the management of the immunosuppression and anti-viral medication in transplant recipients. Herein we describe our experience managing five patients with coronavirus disease 2019 (COVID-19) immediately after kidney transplant. Description: we describe a series of five transplant recipients. Two were submitted to a low immunological risk induction immunosuppression: one developed severe disease, the other developed critical disease. The remaining three were submitted to a high immunologic risk immunosuppression: one developed mild disease, but approximately two months after diagnosis developed moderate COVID-19; another developed severe COVID-19; the remaining patient developed critical illness and perished. Both patients with critical COVID-19 developed bacterial and fungal superinfections in the Intensive Care Unit. All eligible patients were submitted to remdesivir and dexamethasone. The anti-metabolite was reduced or suspended. Despite worsening kidney function during the acute phase, kidney replacement therapy was only needed in one patient and the average serum creatinine at the time of discharge was lower that the pre-COVID-19 nadir. Discussion: There is still no definitive answer on whether solid organ transplant recipients carry a higher risk for morbimortality. Risk factors for the general population can also affect their outcome. The prolonged viral shedding in recipients may explain the irregular evolution of the patient who developed COVID-19 months after the initial diagnosis. The reduction of immunosuppression can be problematic in early post-transplant, but no apparent signs of rejection were noted. Literature addressing this specific context is scarce and studies are needed to clarify the optimal management of these patients.
Membranoproliferative glomerulonephritis: A rare pediatric nephropathy
Authors:   Pediatric Resident, Hospital Pediátrico – Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Marinhas Andreia , Luís Telma ,   Pediatric Resident, Pediatrics Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, Neves Catarina ,   Pediatrician, Unidade de Nefrologia Pediátrica, Hospital Pediátrico – Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Carmo Carmen ,   Pediatric Nephrologist, Unidade de Nefrologia Pediátrica, Hospital Pediátrico – Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Gomes Clara ,   Pediatric Nephrologist, Unidade de Nefrologia Pediátrica, Hospital Pediátrico – Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
Published: March 2022

Membranoproliferative glomerulonephritis is a rare chronic glomerulonephritis in pediatric age. It may be a primary disorder or secondary to other chronic diseases. Diagnose of membranoproliferative glomerulonephritis is based on specific kidney biopsy findings. The prognostic factors, the outcome and the most suitable treatment regimen are incompletely known in children. We report a case of a 3-year-old boy that presented with nephritic/nephrotic syndrome and hypocomplementemia. After 10 days under corticosteroid therapy, he maintained worsening of renal function and a renal biopsy specimen revealed a membranoproliferative glomerulonephritis. Autoimmune disease and infections were initially excluded, but further investigation revealed positive Polymerase Chain Reaction for cytomegalovirus in blood and urine. Cytomegalovirus genome at biopsy was not identified. He completed six months of treatment with valganciclovir and corticosteroids with total remission of proteinuria and undetected viral loads. With this case, we would like to draw attention to a type of nephropathy that is rare in childhood.
Thrombotic microangiopathy in a patient with a poorly controlled human immunodeficiency virus infection – A clinical case
Authors:   Serviço de Nefrologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Castro Pedro , Oliveira Nuno ,   Serviço de Nefrologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Alves Rui ,   Serviço de Nefrologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal,   Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal
Published: March 2022

A 56-year-old male with a poorly controlled human immunodeficiency virus infection presents to the emergency room due to anorexia and weight loss. The patient was emaciated, hypertensive and his laboratory tests showed thrombocytopenia, anaemia, an elevated lactate dehydrogenase and an acute kidney injury. The patient was admitted to the Infecciology ward and by the fourth day, as the kidney function did not improve, a Nephrology consultation was requested. We collected a full auto-immune and serological panel and a urinalysis to rule out glomerular pathologies. Two days later, the patient developed a hypertensive emergency associated with an acute respiratory distress, responsive to furosemide and anti-hypertensive medications. The complementary study showed a high LDH, unmeasurable haptoglobin, thrombocytopenia and schizocytes on peripheral blood smear. These findings suggested a thrombotic microangiopathy associated with human immunodeficiency virus infection and so, he restarted antiretroviral therapy. The kidney function deteriorated and, despite starting haemodialysis, the patient died shortly after.
GASTRONOMİ TURİZMİ KAPSAMINDA SOKAK LEZZETLERİNİN İNCELENMESİ: ESKİŞEHİR ÖRNEĞİ
Authors: ŞİMŞEK Aykut , ÇELİK YEŞİL Seher
Published: March 2022

Bu çalışmada Eskişehir’deki sokak lezzetlerinin neler olduğunun, bunların tüketim sebeplerinin, bu lezzetlerin içerisinde göçmenlerin rolünün, olumlu/olumsuz ekonomik, kültürel, çevresel ve hijyen bakımından etkilerinin belirlenmesi amaçlanmaktadır. Ayrıca mevcut sokak lezzetleri dışında Eskişehir mutfağına ait, potansiyel sokak lezzetleri olabilecek yemeklerin/ürünlerin belirlenmesi de çalışmanın bir diğer amacını oluşturmaktadır. Araştırma doğrultusunda kartopu örneklem yöntemiyle işletme ve tüketiciler araştırma kapsamına alınarak yarı yapılandırılmış görüşme tekniği kullanılmış ve bu kapsamda yer alan 18 kişi ile 29 Mayıs-12 Haziran 2021 tarihleri arasında yüz yüze görüşmeler yapılarak veriler toplanmıştır. Yapılan görüşmeler sonucunda elde edilen sokak lezzetlerinin oldukça çeşitli olduğu (köfte, çibörek, boza vb.) ve Eskişehir’in mevcut lezzetler dışında önemli bir potansiyele (mercimekli ve nohutlu mantılar, Sivrihisar baklavası vb.) sahip olduğu belirlenmiştir. Sokak lezzetlerinin ekonomik, kültürel ve çevresel yönden olumlu etkilerinin olduğu sonucuna varılmıştır.
YENİ YİYECEK FOBİSİ VE GASTRONOMİ TURİZMİNİN GELİŞMESİNE ETKİSİ: KALİTATİF BİR ÇALIŞMA
Authors: TÜRKER Nuray , AKMANOĞLU Emre
Published: March 2022

Gastronomi turizminin önemli bir gelişme kaydettiği günümüzde insanlar yeni yiyecekler denemek, böylece destinasyonun kültürünü ve ürünlerini yiyecek ve içecekler yoluyla deneyimlemek için seyahat etmektedir. Bununla birlikte, yeni ürünler deneyimlemek isteyenler kadar yeni ve aşina olmadıkları yiyecek ve içeceklerden korkan insanlar da bulunmaktadır. Yiyecek neofobisi olarak adlandırılan bu korkular gastronomi turizminin gelişmesini olumsuz yönde etkilemektedir. Bu bağlamda bu çalışmanın temel amacı, kişilerin yeni yiyecek fobilerini belirlemek ve yiyecek neofobisinin gastronomi turizminin gelişimi üzerindeki etkisini ortaya koymaktır. Çalışmada nitel bir araştırma deseni benimsenmiş olup amaçlı örnekleme yöntemi kullanılarak daha önce yurt dışına seyahat etmiş 16 kişi ile online görüşme yapılmıştır. Araştırmada yeni yemek deneyiminin kültür, din, hijyen gibi durumlardan etkilendiği belirlenmiştir. Çalışma, yiyecek neofobisinin gastronomi turizminin gelişmesini olumsuz yönde etkilediğini göstermektedir.
An Analysis of the Communicative Competence Level of Students: A Case of Nursing Students in a State University in Nothern Philippines
Authors: Eustaquio Ma. Theresa
Published: March 2022

For several years, the linguistic ability of student-nurses has been assessed using standardized tests. To assess their overall communicative competence level (linguistic, discourse, sociolinguistic, and strategic competencies), the researcher made use of a self-made, reliable, and valid communicative assessment packet. As a result, the assessment of the level of communicative competence of the student nurses revealed that they are advanced in terms of linguistic, discourse, sociolinguistic, and strategic competencies. The outcomes of the study proved further that student nurses have a broad knowledge of their field, possess a high level of communicative competencies, and effectively practice professional, technical and soft skills involved in the world of quality nursing care. However, additional language lessons and activities which are aligned to clinical and hospital settings may still be added to the BSN curriculum for the student nurses to reach the competent level.
Advertising Appeals influencing the Brand Engagement of Gen Y and Z in terms of Social Media Pre-roll Advertisements
Authors: De Leon Erll Angelo , Resuta Ma. Bianca , Virtusio Derie Rose
Published: March 2022

This study focused on how advertising appeals affect the brand engagement of Generations Y and Z in terms of pre-roll advertisements found on Facebook and YouTube. The objective of this study was to know what specific advertising appeal captures the attention of both Gen Y and Gen Z, as well as enumerate what advertising appeal captures their attention individually. Lastly, to identify which particular advertising ABPs increase the brand engagement of Gen Y and Z. According to studies, three advertising appeals positively affect brand engagement; Emotional Appeals, Visual Appeals, and Ethical Appeals. A total of 300 respondents answered the online survey via Google forms, 145 respondents for Gen Y and 155 respondents for Gen Z. The survey questionnaire was conducted with three different parts, which are; Profiling, Ad testing, and General Questionnaire. To answer the different research questions in this study, the following statistical treatment tools were used; Kruskal-Wallis H Test and Post Hoc Test, Mann-Whitney U Test, and Multivariate Regression Analysis, all at 0.05 and 0.1 levels of significance. For the results of this study, the researchers found out that Ethical pre-roll advertisements capture Gen Z's attention using the Post Hoc Test. On the other hand, Emotional pre-roll advertisements capture Gen Y's attention based on the Mann-Whitney U Test. The study successfully identified advertising ABPs of the Gen Y and Z that significantly influenced their brand engagement. If these ABPs garnered a high score, the probability of a high brand engagement score towards the particular pre-roll advertising appeal also increases.
An Assessment: The Philippine Outstanding Debt and other Economic Determinants towards its Implication on Economic Growth
Authors: Santos Bianca Mari , Serrano Kiana Siena , Pigao Kevin Jamir
Published: March 2022

The ability to generate funds is crucial to a country's economic progress. Following the government's monetary and fiscal policies, an adequate quantity of money must be made accessible. The Philippines is no exception to borrowing. The Philippine government borrows money to pay for public goods and services, fostering economic security. The Philippine debt would increase over time due to the need to satisfy economic needs, especially now that economic development has slowed to the point of negative GDP growth and financial markets have been badly damaged by the pandemic. The goal of this study is to look at the Philippines' present condition in terms of public debt and other economic factors and see how public debt and other economic drivers affect the country's real GDP growth rate. Data from the Philippine Bureau of Treasury and the Philippine Statistics Authority were used to calculate the corresponding public debt and real GDP growth rates from 1986 to 2020. The impact of public debt and other economic variables on economic growth, as represented by the variable real GDP growth rate, was estimated using multiple regression. Furthermore, the results show that the relationship between public debt and real GDP growth is insignificant in the short run. The inflation rate, population growth, openness, and gross capital formation have no significant relationship with real GDP growth. In contrast, government consumption has a significant relationship with the real GDP growth rate. The findings might aid the National Economic Development Authority, and the government analyze the state of our economy and, as a result, strengthen the country's economic policies.
Market Orientation, Learning Orientation and Innovation Performance: The Mediation of Knowledge Management
Authors: Wahyuni Ni Made , Giantari I Gusti Ayu Ketut
Published: March 2022

Internationalization of small and medium enterprises (SMEs)  contributes as a driver of the economy. It is important for SMEs to produce innovation performance. The aim of the study was to investigate the relationship between market orientation (MO), learning orientation (LO), and knowledge management (KM) on innovation performance. The research method is a cross-sectional research design. The population include export-oriented manufacturing SMEs, registered with the Bali Province Industry and Trade Office (2019). A total of 94 senior SME managers participated in the survey. Partial least square (PLS) based structural equation model was used to test the hypothesis. Finding, KM plays a mediating role in the relationship between MO and LO on innovation performance. Managers’ policies in the practice of strategic orientation and knowledge management strengthen innovation performance.
Sosialisasi Dampak Sex Bebas Bagi Kesehatan Dan Jiwa Di Lokasi Wisata Desa Bira Bulukumba Sulawesi Selatan
Authors: Makmun Armanto , Muchsin Achmad Harun
Published: March 2022

Saat ini, generasi muda di seluruh dunia berusia 10-24 tahun mencapai 1,8 miliar orang dan menjadi populasi terbesar. Berdasarkan data Badan Kependudukan dan Keluarga Berencana Nasional (2012), jumlah remaja yang pernah berciuman adalah 93,7%, 97% pernah menonton film porno, 62,7% mengaku tidak perawan dan 21,2% melakukan aborsi. Perilaku tersebut dapat menimbulkan berbagai dampak negatif bagi mereka, antara lain rentan terhadap penyakit kelamin dan tertular HIV/AIDS, kehamilan yang tidak direncanakan, penggunaan narkoba, dan gangguan psikologis. Asisten Deputi Perlindungan Anak dari Kekerasan dan Eksploitasi, Valentina Ginting mengatakan, banyak tindakan kekerasan terhadap perempuan dan anak, eksploitasi seksual dan pekerja anak cenderung terjadi di tempat-tempat yang memiliki banyak kegiatan ekonomi, terutama di kawasan wisata, misalnya di Tanjung Bira. Target yang dicapai dalam penyampaian ini adalah untuk meningkatkan pemahaman masyarakat tentang pentingnya pendidikan seks untuk kesehatan dan kesehatan mental di Kawasan Wisata Desa Bira, Bulukumba, Sulawesi Selatan.
Soil Microbiome and Banana Plant Diseases: A Review
Authors: Nur Aina Mardhiah Zolkhairi  , Ismail Ismatul Nurul Asyikin
Published: March 2022

Soil microbiomes not only benefits the ecosystem, such as facilitating nitrogen cycling, but they can also cause unhealthy plant or even death since some of the microbes are pathogens. The crops yield will significantly decrease if the pathogens are still assembled in the soil, which could cause losses to farmers. Previous studies have acknowledged several aspects of the roles of soil microbiome and how soil variations can affect the availability and functions of the microbes. Banana is one of the most popular, commonly consumed, and essential fruit crops worldwide. Nevertheless, the accumulation of pathogenic microorganisms as primary inhabitants in the soil become a main limiting factor in banana crops production. With current studies and technologies, the disease caused by pathogenic microbes in the soil can be controlled. The scope of this review is on soil microbiomes that contribute to banana plant diseases and the methods to control the disease.
Parameter Determination and Drive Control Analysis of Axial Flux Permanent Magnet Synchronous Motors
Authors: Nyitrai Attila , Szabó Gergely , Horváth Sándor R.
Published: March 2022

Axial flux electric motors have received a lot of attention in recent years due to successful implementations in industrial or traction applications. Particularly, axial flux permanent magnet synchronous motors (AFPMSM) can be an attractive choice in case of high torque-density requirements or when the drive environment (packaging) is geometrically limited to a disc-shaped motor. However, compared to radial flux motors, axial flux machine modeling possibilities are much less documented. In the present study, different electromagnetic modeling approaches have been compared through an example AFPMSM design. The motor parameters were determined by analytical and finite element methods. A 2D equivalent model (2D Linear Motor Modeling Approach – 2D-LMMA) and a 3D model results have been compared. The calculated values were used to carry out a drive control analysis of the axial flux motor.
The glycolytic enzyme PFKFB3 determines bone marrow endothelial progenitor cell damage after chemotherapy and irradiation
Authors: Lyu Zhong-Shi , Tang Shu-Qian , Xing Tong , Zhou Yang , Lv Meng , Fu Hai-Xia , Wang Yu , Xu Lan-Ping , Zhang Xiao-Hui , Lee Hsiang-Ying , Kong Yuan , Huang Xiao-Jun
Published: March 2022

Bone marrow (BM) endothelial progenitor cell (EPC) damage of unknown mechanism delays the repair of endothelial cells (EC) and recovery of hematopoiesis after chemo-radiotherapy. We found increased levels of the glycolytic enzyme PFKFB3 in the damaged BM EPC of patients with poor graft function, a clinical model of EPC damage-associated poor hematopoiesis after allogeneic hematopoietic stem cell transplantation. Moreover, in vitro the glycolysis inhibitor 3-(3-pyridinyl)- 1-(4-pyridinyl)-2-propen-1-one (3PO) alleviated the damaged BM EPC from patients with poor graft function. Consistently, PFKFB3 overexpression triggered BM EPC damage after 5-fluorouracil treatment and impaired hematopoiesis-supporting ability in vitro. Mechanistically, PFKFB3 facilitated pro-apoptotic transcription factor FOXO3A and expression of its downstream genes, including p21, p27, and FAS, after 5-fluorouracil treatment in vitro. Moreover, PFKFB3 induced activation of NF-κB and expression of its downstream adhesion molecule E-selectin, while it reduced hematopoietic factor SDF-1 expression, which could be rescued by FOXO3A silencing. High expression of PFKFB3 was found in damaged BM EC of murine models of chemo-radiotherapy-induced myelosuppression. Furthermore, a murine model of BM EC-specific PFKFB3 overexpression demonstrated that PFKFB3 aggravated BM EC damage, and impaired the recovery of hematopoiesis after chemotherapy in vivo, effects which could be mitigated by 3PO, indicating a critical role of PFKFB3 in regulating BM EC damage. Clinically, PFKFB3-induced FOXO3A expression and NF-κB activation were confirmed to contribute to the damaged BM EPC of patients with acute leukemia after chemotherapy. 3PO repaired the damaged BM EPC by reducing FOXO3A expression and phospho-NF-κB p65 in patients after chemotherapy. In summary, our results reveal a critical role of PFKFB3 in triggering BM EPC damage and indicate that endothelial-PFKFB3 may be a potential therapeutic target for myelosuppressive injury.
Preclinical evaluation and structural optimization of anti-BCMA CAR to target multiple myeloma
Authors: Harush Ortal , Asherie Nathalie , Kfir-Erenfeld Shlomit , Adler Galit , Barliya Tilda , Assayag Miri , Gatt Moshe E. , Stepensky Polina , Cohen Cyrille J.
Published: March 2022

Chimeric antigen receptor (CAR) T-cell based immunotherapy has become a promising treatment mainly for hematological malignancies. Following the major success of CD19-targeted CAR, new potential targets for other malignancies are required. As such, B-cell maturation antigen (BCMA) is an attractive tumor-associated antigen to be targeted in multiple myeloma (MM). Herein, we aimed at assessing the function and optimal configuration of different BCMA-specific CAR, based on the same targeting moiety but with a different hinge and co-stimulatory domain. We compared their function to that of a previously characterized BCMA-CAR used in clinical trials. All constructs were expressed at high levels by primary human T cells and could trigger cytokine production and cytotoxicity upon co-culture with multiple myeloma targets. Nonetheless, critical differences were observed in off-target activation, exhaustion, and activation marker expression and in vivo antitumoral activity mediated by these different constructs. Interestingly, we noted that CD8-based hinge, combined with a 4-1BB intracellular domain, proved superior compared to IgG4-connecting regions, and/or a CD28-signaling moiety respectively. Overall, this study emphasizes the influence of CAR primary structure on its function and led to the identification of a highly efficient BCMA-specific CAR, namely H8BB, which displayed superior anti-tumoral activity both in vitro and long-term in vivo efficacy.
The Changes of Family Food Patterns in Two Generations in Padang Genting Village, Batubara Regency (In terms role of women as housewives)
Authors: Maswita
Published: March 2022

Changes in family dietary habitary patterns are necessary, although some families persist in generations of family dietary habits. Dietary habit is related to the physical needs of healthy and sustainable living. Some areas in Indonesia, family eating patterns tend to be oriented to family habits from generation to generation. This study aims to analyze the factors that influence housewives in the second generation in compiling their family's dietary habit in the coastal area of the Malacca Strait. This study was conducted in Padang Genting Village, Batubara Regency, North Sumatra. The method used in this study is the ethnographic method with participant observation techniques and in-depth interviews with selected respondents based on the snowball technique and direct observation in the research area. The results of this study concluded that the experience of housewives with their parents, formal education and experience in PKK (Family Welfare Development) in villages and sub-districts also became the basis for women housewives to formulate their family's dietary habitary habit.
Impact of Anthropogenic Activities on Physico-Chemical Properties of Sediment of Hokersar Wetland: A Protected Wildlife Reserve (Ramsar Site No.1570) Of Kashmir Himalaya
Authors: Bano Haleema , Malik Shaista , Rather Rauoof A , Bhat Javeed Ia , Islam Shaista , Bhat Tariq A , Bhat M Ashraf
Published: March 2022

Impact of anthropogenic activities on physico-chemical properties of sediment of Hokersar wetland was carried in summer, spring and autumn seasons. Sediment at Inlet site was having higher value for physicochemical parameters viz; EC (0.509 dS/m), available nitrogen (109.86 mg/kg), available potassium (89.97 mg/kg), available phosphorus (10.18 mg/kg), Ca (352.53 mg/kg) and Mg (152.44 mg/kg) except pH which was highest (7.99) at Outlet. The values of all the physico-chemical parameters of sediment were found maximum in summer season and minimum in autumn except for pH which was higher (7.81) in autumn and lower in (7.16) in summer. Highest values for Fe (23.90 mg/kg), Mn (8.54 mg/kg), Cu (3.65 mg/kg) and Zn (2.77 mg/kg) in sediment were found at Inlet site and lowest values for Fe (11.82 mg/kg), Mn (3.52 mg/kg), Cu (0.97 mg/kg) and Zn (1.14 mg/kg) at outlet site. Further, these trace elements were observed in higher concentration during summer season as compared to autumn. This all may be due to the high rate of degradation of huge quantities of waste present in the Wetland.
Bangladesh J. Bot. 51(1): 83-92, 2022 (March)
Effects of Seed Treatment on Seed Quality and Storability In Wheat (Triticum Aestivum L.) In North Western Himalayas
Authors: Thakur Anubhav , Dhiman KC , Kanwar Rajesh
Published: March 2022

Storage experiment was conducted to study effects of polymer, fungicides and insecticide on seed quality parameters and storability in wheat. Experimental material consisted of carry over wheat seeds (variety HPW-155) of rabi 2017 - 18. Different parameters namely, germination, seedling length, dry weight, vigour index - I, vigour - II, speed of germination, field emergence, 100-seed weight for 12 months of storage were recorded bimonthly. All parameters were found to decrease with the advancement in storage period. Results showed that seeds treated with polymer + vitavax 200 @ 2 g/kg of seed recorded higher germination percentage (95.00), seedling length (17.58 cm), seedling dry weight (0.0138 g), vigour index - I (1670) and vigour - II (1.311), speed of germination (19.98), 100-seed weight (5.54 g). Field emergence (87.33) were at par with vitavax 200 @ 2 g/kg of seed over untreated control. For the purpose of maintaing seed quality and enhancing storability, seed of wheat can either be treated with polymer @ 3 ml/kg of seed + vitavax 200 @ 2 g/kg of seed or vitavax 200 @ 2 g/kg of seed.
Bangladesh J. Bot. 51(1): 113-121, 2022 (March)
Identification of Volatile Components of Flowers Of Zephyranthes Candida (Lindl.) Herb.
Authors: Yang Chen Xiang , Feng Bi Shu
Published: March 2022

The volatile components of Zephyranthes candida flowers were extracted using headspace-solid phase micro-extraction (HS-SPME) technique and then were analyzed by gas chromatography-mass spectrometry (GC-MS) for the first time. The major compounds of volatile extract were found to be 1-hexanol (15.4%), methyl heptanoate (12.8%), hexyl acetate (4.9%), 2-acetyl pyrrole (3.6%), methyl-α-D-rhamnopyranoside (3.0%), phenethyl alcohol (2.8%), heptanoic acid (2.7%), and 1-octanol (2.1%).
Bangladesh J. Bot. 51(1): 175-178, 2022 (March)
Sociodemographic and Reproductive Factors Associated with Breast Cancer: A Case-Control Study in a Cancer Specialized Hospital of Dhaka City, Bangladesh
Authors: Zahed Zerin , Hossain Ahmed
Published: March 2022

Background: Breast cancer is the most common cancer in women in the world. In Bangladesh, the breast cancer is estimated to have the age-standardized incidence rate of 25.2 per 100,000 females of all ages.

Objective: The objective of this study was to identify the sociodemographic and reproductive factors associated with the development of breast cancer in Bangladesh.

Materials and method: A case control study was conducted on 136 female subjects, in a cancer specialized hospital of Dhaka city (68 subjects for case group with breast cancer and 68 subjects for control group without any known cancer) aged ≥20 years. Data was collected by face to face interview with structured questionnaire. The results were reported by adjusted odd ratios (ORs) and corresponded 95% confidence intervals (CIs). A p-value less than 0.05 were considered statistically significant. Independent factors associated with breast cancer were established using multivariate logistic regression analysis.

Result: Among the reproductive factors, women with the history of hysterectomy are 84% less likely and post-menopausal women are 27.83% more likely to get breast cancer. On sociodemographic background women who received 12+ years of schooling and 6 to 10 years of education are 14.91% and 4.91% more likely to get breast cancer. Women with the monthly family income of 5000 Tk to 25000 Tk are 76% less likely to get breast cancer than women with more monthly family income. Women married for more than 20 years are 7.27% more likely to get cancer. Women with 3 or more children are 81% less likely to get breast cancer than women with fewer children.

Conclusion: Our study suggests that, age, level of education, monthly family income, history of hysterectomy of the patient may play an important role in risk of breast cancer in Bangladeshi women. Further research is needed to better understand the complex interactions between environmental, reproductive and genetic factors.

Delta Med Col J. Jul 2020 8(1): 4-8
Incidental Diagnosis of Bicornuate Uterus in a Lady of 48 Years - A Case Report
Authors: Parveen Rafia , Rahman Shaikh Shofiur
Published: March 2022

Congenital anomalies of uterus are not very uncommon. Quite a number of women with these anomalies can be totally asymptomatic. In some women, anomalies may be first detected during pregnancy or delivery. Here a case of incidentally diagnosed bicornuate uterus is reported in a lady of 48 years while being treated for breast carcinoma. The patient attended with a lump in her left breast at Delta Medical College Hospital, Dhaka, Bangladesh. She was totally asymptomatic previously and her three children were born preterm without any difficulty. Along with other investigations, abdominal ultrasonogram was done which showed two separate fundal and uterine cavities with single cervix. Bicornuate uterus was confirmed by endovaginal ultrasonogram. Breast carcinoma was treated accordingly.

Delta Med Col J. Jul 2020 8(1): 46-50
IMPLEMENTATION OF CONCOLIC UNIT TESTING IN TESTING BINARY SEARCH ALGORITHM USING JCUTE
Authors: Feta Neneng Rachmalia , Fitria Fitria
Published: March 2022

Testing is a process of implementing a program with the aim of finding an error. A good test case is one of the tests that have the possibility of finding an undisclosed error. One of the existing types of testing is the Concolic Unit Testing Engine. In this research, testing is applied using the Jcute tool, which is a tool to systematically and automatically test sequential C programs (including instructions) and Java programs together. This test is carried out on the search function of an element of data in the Binary Search Search Algorithm. However, to check whether concolic testing can detect bugs in the software practically through case studies. This research describes a case study of the application of a test tool to a Java application. Through this research, we tested the path coverage and Branches Covered. We can also find out the details of total branches covered; total functions invoked, percentage of branches covered and the number of iterations. JCUTE can also find an interleaving of two sequences or circuits that results in an infinite loop.
Student Drowsiness During Simulated Solo Flight
Authors: Corbett Mark A. , Newman David G.
Published: March 2022

INTRODUCTION: Pilot fatigue is a significant concern in aviation, where efforts are directed at improving rosters, developing models, and improving countermeasures. Little attention has been given to in-flight detection of fatigue/drowsiness. The aims of this research were to
determine whether drowsiness is an issue and explore whether infrared reflectance oculography could prove useful for continuous inflight monitoring.METHODS: Nine university-based pilot trainees wore activity monitors and completed diaries, prior to a simulated navigational exercise
of approximately 4 h, during the secondary window of circadian low. During the flight they wore a head-mounted device. Oculographic data were collected and converted into a single number, using the Johns Drowsiness Scale (JDS), with increasing values indicating greater drowsiness (range 0.0
to 10.0).RESULTS: Peak JDS values reached 6.5. Values declined from shortly before top of descent, continuing until landing. Two of the nine participants (22.2%), reached drowsiness levels at or above a cautionary warning level, below which is considered safe for driving a motor
vehicle.DISCUSSION: The results of this study revealed the timeline and levels of fatigue that might be experienced by student pilots; showing that drowsiness is a potential issue for student pilots operating in flying conditions similar to those in the simulation. Analysis indicated
that pilots are likely to experience levels of drowsiness above a cautionary warning level when modeling predicted effectiveness below 90%, indicating a potential drowsiness issue for pilots. It was concluded that oculography is worthy of further investigation for use as an objective fatigue
detection tool in aviation.Corbett MA, Newman DG. Student drowsiness during simulated solo flight. Aerosp Med Hum Perform. 2022; 93(4):354–361.
Optic Disc Edema in Astronauts from a Choroidal Point of View
Authors: Wostyn Peter , Gibson Charles R. , Mader Thomas H.
Published: March 2022

INTRODUCTION: Optic disc edema has been well documented in astronauts both during and after long-duration spaceflight and is hypothesized to largely result from increased pressure within the orbital subarachnoid space brought about by a generalized rise in intracranial pressure
or from sequestration of cerebrospinal fluid within the orbital subarachnoid space with locally elevated optic nerve sheath pressure. In addition, a recent prospective study documented substantial spaceflight-associated peripapillary choroidal thickening, which may be a contributing factor
in spaceflight-associated neuro-ocular syndrome. In the present article, based on the above, we offer a new perspective on the pathogenesis of microgravity-induced optic disc edema from a choroidal point of view. We propose that prolonged microgravity exposure may result in the transudation
of fluid from the choroidal vasculature, which, in turn, may reach the optic nerve head, and ultimately may lead to fluid stasis within the prelaminar region secondary to impaired ocular glymphatic outflow. If confirmed, this viewpoint would shed new light on the development of optic disc
edema in astronauts.Wostyn P, Gibson CR, Mader TH. Optic disc edema in astronauts from a choroidal point of view. Aerosp Med Hum Perform. 2022; 93(4):396–398.