bluuebunny/crossref_metadata_2025 huggingface dataset:
PROGRAM EDUKASI URBAN FARMING PENUNJANG KEMANDIRIAN MASYARAKAT DI KELURAHAN PANDEYAN, UMBULHARJO, YOGYAKARTA
Authors: Anggraini Oktiva
Published: February 2022

Pesatnya laju pertumbuhan populasi penduduk perkotaan berdampak pada timbulnya masalah lingkungan dan ketahanan pangan. Ruang terbuka hijau terbatas, pemenuhan kebutuhan pangan yang terjangkau semakin sulit. Salah satu solusinya adalah melalui Kegiatan Program Edukasi Urban farming pada masyarakat. Program ini dilakukan di kelurahan Pandeyan, kecamatan Umbulharjo, Yogyakarta selama tiga bulan. Pendekatan yang dilakukan pada program pengabdian ini yakni dengan teknik penyuluhan dan praktek. Metode ceramah berupa presentasi materi oleh narasumber yang meliputi budidaya tanaman hidroponik dalam baskom, budidaya tanaman bawang dalam polibag dan polikultur tanaman sayuran dalam polibag. Hasil kegiatan pengabdian masyarakat menunjukkan pengetahuan dan ketrampilan peserta pelatihan tentang pertanian perkotaan meningkat. Teknologi budidaya tanaman dalam polibag di rumah paling banyak diterapkan karena efisien. Ketrampilan tentang macam-macam teknologi pertanian perkotaan dapat diterapkan di lahan sem pit dan lorong kampung. Kegiatan dinilai dapat meningkatkan ketahanan pangan rumah tangga. Potensi warga yang kreatif dipadu entrepreneurship yang baik perlu didorong mengoptimalkan dalam penataan kampungnya lebih menarik, sekaligus menunjang ketahanan pangan. Luaran: rekayasa sosial dan publikasi di media sosial dan seminar
ATAS NAMA ISLAM: KAJIAN PENOLAKAN HIZBUT TAHRIR INDONESIA (HTI) TERHADAP PLURALISME
Authors: Setia Paelani
Published: February 2022

This study discuss the views of Hizbut Tahrir Indonesia (HTI) regarding religious pluralism. HTI as an organization that is sincere in interpreting the Qur'an literally and firmly rejects religious pluralism, which many people agree on as a concept that must be applied in Indonesia. This is a logical consequence where Indonesia is inhabited by various religions bound by a sense of unity in Pancasila and Bhinneka Tunggal Ika. For HTI, this is a failure of the state to build and maintain the unity that Islam should bind through a single power (Khilafah Islamiyah). This concept has been widely criticized by scholars based on two approaches, namely the Qur'an and sociological. Clearly, the Qur'an has acknowledged the existence of pluralism through the existence and truth of the books before the Qur'an, the acknowledgment of prophets and apostles other than the 25 people, as well as the acknowledgment of the Qur'an for the existence of other religions. HTI's rejection of pluralism was also refuted by HTI's own inconsistencies as the attitude of rejecting globalization but acting as a player of globalization, the attitude of rejecting democracy but taking advantage of the openness of freedom of opinion as a result of democracy, and  the attitude of blaming the system of liberalism and secularism as the factors that give rise to deviant religious sects are purely psychological and sociological factors.
PENGGUNAAN APLIKASI YOUTUBE SEBAGAI MEDIA DAKWAH DI ERA PANDEMI COVID-19
Authors: I Makna A’raaf K  , Prihantoro N P  , Larasati Sifa , M. Fais Noor M  , Hisny Fajrussalam
Published: February 2022

The existence of the Covid-19 pandemic is the background for holding this research, in which health protocols prohibit and limit activities that gather large numbers of people. This also has an impact on religious activities such as da'wah which require alternative solutions, because previously it was carried out face-to-face and gathered. The alternative offered in this study is through the social media platform Youtube. The purpose of this study is to analyze whether the Youtube platform is effectively used for preaching and to find out the methods applied in da'wah through the Youtube platform. This study uses a qualitative method, where data is collected from reliable sources such as explanations of the Qur'an and Hadith. The results of this study indicate that da'wah through the Youtube platform in the era of the Covid-19 pandemic has several advantages compared to conventional da'wah. Youtube has many advantages, such as being widely accessed by various groups in terms of sharing video content. Youtube and da'wah also have a relationship with segmentation that both target audiences. In this case, it is hoped that ustaz, scholars, and preachers can use Youtube media by using the available features. This also needs to be followed by good and correct da'wah methods in accordance with Islamic teachings.
FAMAJAL (Potret Tradisi Pengakuan Kekerabatan Masyarakat Kampung Lilinta Distrik Misool Barat Kabupaten Raja Ampat Melalui Ritual Keagamaan)
Authors: Nawir M. Syukri , Yusuf Muhamad , Umkabu Talabudin , Mayalibit M. Yasin. U.N. , Maryati Sulis
Published: February 2022

Famajal is a kinship model that can be found in Papua. This tradition is carried out in religious rituals such as Aqika and Khitan. To strengthen kinship needed donations in the form of money from relatives and guests. In this tradition, there is an acknowledgment of kinship spoken by the money giver and singing a folk song about kinship. This study uses qualitative methods, verbs of social phenomenology with the research area in Lilinta village. the analysis model uses interpretive. The results of the study include 1. Religious rituals in Lilinta such as study in Islamic studies for children, Reciting Surah Yaseen by women, entering new homes accompanied by recitation of the prayer of Manakib, and Reciting Tahlil are a religious unit that is maintained in religious life in the Lilinta village community. 2. Religion can adapt to local culture so cause changes at the surface level. 3. No written source reveals about this tradition so that the tradition has shifted. 4. Not all religious rituals carried out in Lilinta village are combined with Famajal. 7. In Aqikah and Khitanan is not merely ceremonial, in the ritual the child is introduced about the kinship that exists in the family environment with various advice given. 8. Tradition can develop the beliefs, knowledge, and habits (meaning) of the local community which is unique and underlies mutual understanding, develops further interactions and actions in community life and knowledge about kinship.
Staying or leaving? Teacher professional characteristics and attrition in Arizona traditional public and charter schools
Authors: Pivovarova Margarita , Powers Jeanne M.
Published: February 2022

In this study, we analyzed public school teacher employment data from 2009 to 2015 to understand why teacher attrition is 54% higher in charter schools compared to traditional public schools. We investigated the factors associated with the differences in exit rates of teachers from traditional public and charter schools in Arizona which has a large charter school sector. Our findings suggest that the major factors behind the gap in retention rates between school sectors in Arizona are teachers’ professional characteristics: less experienced teachers and teachers with alternative certification are more likely to exit schools and, in particular, charter schools which also employ a significantly larger share of these teachers. We argue that charter school and school district leadership might consider interventions, mentoring, and support for teachers in the early stages of their career targeted at novice teachers.
A Framework of Location-Based Advertising Effectiveness: Perspectives of Perceived Value and Satisfaction
Authors:   Department of Economic Information System & Electronic Commerce, Thuongmai University, Vietnam, Le Xuan Cu , Nguyen Tran Hung ,   Department of Economic Information System & Electronic Commerce, Thuongmai University, Vietnam
Published: February 2022

The power of innovative positioning technology and the prevalence of mobile handheld devices have benefited prominently the interactions between businesses and consumers via modern interactive marketing channels. Location-based advertising (LBA) is a salient instance. It is imperative for marketers to understand thoroughly a mechanism of consumers’ value perceptions in LBAs and the motivations for their buying decisions to advertised brands. A research model is constructed based on the Choice Value Model (CVM) to identify a range of important factors navigating perceived value, satisfaction and behavioral intentions toward LBAs. A survey of 306 mobile users in Vietnam was gathered. The findings revealed that content quality generates the strongest signal for predicting perceived value, whereas advertising perception is investigated to be the lowest indicator. Moreover, perceived value closely relates to satisfaction, continuance intention and buying inclination. Otherwise, satisfaction is unveiled as a necessary catalyst to quicken buying inclination in LBAs. Finally, theoretical implications and hints for Asian business are discussed.
Modeling Business vs Non-Business Students Blended Learning Experience: Invariance Assessment and Multigroup Analysis
Authors:   Faculty of Business and Management, Universiti Teknologi MARA, Malaysia, Nasirun Noraini ,   School of Management, Universiti Sains Malaysia, Malaysia, Ramayah Thurasamy ,   School of Management, Universiti Sains Malaysia, Malaysia,   Daffodil International University (DIU), Bangladesh, Malaysia,   Faculty of Economics and Business, Universiti Malaysia Sarawak (UNIMAS), Malaysia, Khalid Shaiful Annuar ,   Faculty of Business and Management, Universiti Teknologi MARA, Malaysia, Shahruddin Shafiq ,   Faculty of Business and Management, Universiti Teknologi MARA, Malaysia
Published: February 2022

Usually, business students perform better in entrepreneurship subjects as compared to non-business students. This study aims to compare performance between business and non-business students. Five variables (student engagement, student interactions, satisfaction, efficiency, and effectiveness) were included in the research framework as this study was underpinned by the Social Constructivism Approach. The study used a structured questionnaire to collect data from business students and nonbusiness students who were enrolled in the course Fundamental of Entrepreneurship. The data for the study was analyzed using SmartPLS 3.3.3. First, the invariance of measurement items was assessed using the Permutation analysis and then we ran a multigroup analysis to assess the measurement, structural model and group comparison. The results of this study reveal a significant difference between the positive direct effect between student interaction and effectiveness among business and non-business students. The results also show a significant difference between the indirect effect between student engagement and effectiveness among the compared groups. This study contributes to the literature within the spectrum of the Social Constructivism Approach. Moreover, the study outlines practical contributions to the higher learning institutions that use the online learning approach for large classrooms.
Effect of Flame Treatment and Radiofrequency Electromagnetic Radiations on phenolic content in in vitro cultures of Ipomoea batatas
Authors: Bag Urja , Narasimhan S , Bindu S
Published: February 2022

In vitro grown callus cultures of Ipomoea batatas were exposed to flame treatment and electromagnetic radiations generated by mobile phone. The cultured tissues responded to the treatments as evidenced by the significant reduction of phenolic contents compared to controls. Even though the growth of the tissues was normal, there was a change in the phenolic content of the tissues. There exhibited not much significant variation among the treatments regarding the growth rate. The morphology and texture of the callus also remained the same. It has been concluded that like animal cells, plant cells also respond to non-ionizing radiations like electromagnetic radiation emitted by mobile phones.
Experimental Study on Progressive Damage Evolution in Rocks Subjected to Post-peak Cyclic Loading History
Authors: Taheri Abbas , Shirani Faradonbeh Roohollah , Munoz Henry
Published: February 2022

Because of the release of in situ rock stress, rocks surrounding deep underground excavations are mostly driven into a post-peak damage state. Thus, investigations on cyclic loading-induced damage of rocks are of paramount significance in terms of the long-term stability of rock structures. In this study, using a damage-controlled testing method, the effect of post-peak cyclic loading on the failure behavior of different rock types was comprehensively evaluated. This investigation revealed that post-peak cyclic loading imposes no significant influence on the overall failure behavior of rocks. The evolution of damage variables also indicated that the large portion of axial strain damage (Da) occurs during the first cycle at the peak strength, whereas lateral strain damage (Dl) evolved more rapidly than Da did in the post-peak regime under further loading and unloading cycles. The cumulative permanent axial strain (∑εap) evolved nonlinearly with the axial stress ratio (σi/σa−peak) in the post-peak regime, which was manifested as sparse-dense-sparse hysteretic loops. A rapid reduction in the crack damage stress ratio was observed for rocks in the initial sparse hysteretic loops, which was followed by a lower decrease rate in the subsequent dense hysteretic loops, and an almost constant value was finally reached in the last sparse hysteretic loops. Furthermore, tangent Young’s modulus (Etan) and Poisson’s ratio (υ) evolved in three main stages: One, Etan first increased and then decreased in the initial sparse hysteretic loops, while υ continuously increased, representing significant deformation in the lateral direction. Two, Etan decreased in the dense hysteretic loops, while υ increased at a higher rate for stronger rocks because of the decrease in Da accumulation. Three, the increase rate of υ declined in the second set of sparse hysteretic loops, and Etan decreased until complete failure occurred.
Configuration and Assessment of a Submersible Fluorometer for Evaluating Fluorescent Dye Deposition
Authors: Larbi Peter A.
Published: February 2022

Fluorescent tracer dyes are popularly used in agricultural spray application studies to evaluate on-target canopy deposition and off-target drift, and the methods/instruments used for evaluating dye deposit must assure reliability of the data generated. A laboratory setup was configured to adapt a submersible fluorometer for controlled and reliable measurement of pyranine dye fluorescence in liquid samples. The system setup was blanked using a clean sample of de-ionized water and calibrated using standard dye solutions of known concentration (100 to 1,000,000 parts per trillion [ppt]) made from two dyes of different levels of purity (pyranine 98 % and pyranine 85 %). Pyranine 85 % fluorescence readings were consistently lower with reduction factor averaging ∼0.62 times that of pyranine 98 % within a range from 500 to 1,000,000 ppt. The results were verified using a standard laboratory fluorometer. Spray deposition assessment of string, plastic card, cotton ribbon, and artificial foliage samplers was accomplished using the configured fluorometer system setup. The results showed no significant difference among dye purity levels (P = 0.430), no statistically significant interaction between dye purity and concentration (P = 0.484), and no statistically significant interaction between dye purity and sampler type (P = 0.173). Consequently, the configured setup can produce measurements with similar quality as the standard laboratory fluorometer and both dyes tested may be equally used for spray deposition and drift assessments, or for similar applications.
Examining the Link Between Neutral and Ambivalent Attitudes: Their Association and their Co-Occurrence
Authors: Hu Danfei , Gasper Karen
Published: February 2022

We examined the link between neutral and ambivalent attitudes. First, we examined whether they are mutually exclusive, in that when one attitude is present, the other is not, or if they co-occur. Second, we examined whether they are negatively associated, such that as ambivalence increases, neutrality decreases. In three studies, participants indicated their positive, negative, neutral, and ambivalent attitudes toward various stimuli. In contrast to both ideas, (objective and subjective) ambivalence and neutrality co-occurred (no mutual exclusivity), and they, at best, depending on how one looked at the association, were only weakly positively or negatively associated (no strong, negative association). Univalent attitudes co-occurred with and were strongly negatively associated with neutral attitudes. These findings conflict with theories and methodologies that assume mutual exclusivity or an inverse association between neutral and ambivalent attitudes, suggesting that researchers should not assume that presence of neutrality suggests a lack of ambivalence.
It Is Written in the Eyes: Inferences From Pupil Size and Gaze Orientation Shape Interpersonal Liking
Authors: Mattavelli Simone , Brambilla Marco , Kret Mariska E.
Published: February 2022

Research has shown that pupil size shapes interpersonal impressions: Individuals with dilated pupils tend to be perceived more positively than those with constricted pupils. Untested so far is the role of cognitive processes in shaping the effects of pupil size. Two preregistered studies investigated whether the effect of pupil size was qualified by partner's attention allocation inferred from gaze orientation. In Experiment 1 (N = 50) partners with dilated pupils were more liked when gazing toward the participant, but less liked when gazing toward a disliked other. Experiment 2 (N = 50) unveiled the underlying mechanism of the pupil-gaze interplay. Pupillary changes led to inferences about the feelings held by the partner toward the gazed target: Larger pupils signaled positive feelings. Crucially, target identity moderated the response of the participants (i.e., liking toward the partner). This work shows the importance of considering the interplay of affective and cognitive eye-signals when studying person perception.
The ZIP3 Zinc Transporter Is Localized to Mossy Fiber Terminals and Is Required for Kainate-Induced Degeneration of CA3 Neurons
Authors: Bogdanovic Milos , Asraf Hila , Gottesman Noa , Sekler Israel , Aizenman Elias , Hershfinkel Michal
Published: February 2022

Tight regulation of neuronal Zn2+is critical for physiological function. Multiple Zn2+transporters are expressed in the brain, yet their spatial distribution and distinct roles are largely unknown. Here, we show developmental regulation of the expression of Zn2+transporters ZIP1 and ZIP3 in mouse hippocampal neurons, corresponding to previously described increase in neuronal vesicular Zn2+during the first postnatal month. Rates of Zn2+uptake in cultured mouse hippocampal neurons, monitored using FluoZin-3 fluorescence, were higher in mature neurons, which express higher levels of ZIP1 and ZIP3. Zn2+uptake was attenuated by ∼50% following silencing of either ZIP1 or ZIP3. Expression of both ZIP1 and ZIP3 was ubiquitous on somas and most neuronal processes in the cultured neurons. In contrast, we observed distinct localization of the transporters in adult mouse hippocampal brain, with ZIP1 predominantly expressed in the CA3 stratum pyramidale, and ZIP3 primarily localized to the stratum lucidum. Consistent with their localization, silencing of ZIP1 expressionin vivoreduced Zn2+uptake in CA3 neurons while ZIP3 silencing reduced Zn2+influx into dentate gyrus (DG) granule cells in acute hippocampal slices. Strikingly,in vivosilencing of ZIP3, but not ZIP1, protected CA3 neurons from neurodegeneration following kainate-induced seizures. Our results indicate that distinct Zn2+transporters control Zn2+accumulation and toxicity in different neuronal populations in the hippocampus and suggest that selective regulation of Zn2+transporters can prevent seizure induced brain damage.

SIGNIFICANCE STATEMENTZinc plays a major role in neuronal function and its dysregulation is associated with neurodegeneration. Multiple zinc transporters are expressed in neurons, yet little is known on their distinct roles. Here, we show that the plasma membrane ZIP1 and ZIP3 zinc transporters are expressed on distinct neuronal populations in the CA3 region of the hippocampus. We show that ZIP1 mediates zinc influx into postsynaptic cells, while ZIP3 is responsible for zinc re-uptake from this synapse into dentate granule cells. We further show that silencing of ZIP3, but not ZIP1, can rescue the postsynaptic cells from kainate-induced neurodegeneration. This suggests that neuronal zinc toxicity and degeneration can be modulated by regulation of specific zinc transporters function.
Prior Expectations in Visual Speed Perception Predict Encoding Characteristics of Neurons in Area MT
Authors: Zhang Ling-Qi , Stocker Alan A.
Published: February 2022

Bayesian inference provides an elegant theoretical framework for understanding the characteristic biases and discrimination thresholds in visual speed perception. However, the framework is difficult to validate because of its flexibility and the fact that suitable constraints on the structure of the sensory uncertainty have been missing. Here, we demonstrate that a Bayesian observer model constrained by efficient coding not only well explains human visual speed perception but also provides an accurate quantitative account of the tuning characteristics of neurons known for representing visual speed. Specifically, we found that the population coding accuracy for visual speed in area MT (“neural prior”) is precisely predicted by the power-law, slow-speed prior extracted from fitting the Bayesian observer model to psychophysical data (“behavioral prior”) to the point that the two priors are indistinguishable in a cross-validation model comparison. Our results demonstrate a quantitative validation of the Bayesian observer model constrained by efficient coding at both the behavioral and neural levels.

SIGNIFICANCE STATEMENTStatistical regularities of the environment play an important role in shaping both neural representations and perceptual behavior. Most previous work addressed these two aspects independently. Here we present a quantitative validation of a theoretical framework that makes joint predictions for neural coding and behavior, based on the assumption that neural representations of sensory information are efficient but also optimally used in generating a percept. Specifically, we demonstrate that the neural tuning characteristics for visual speed in brain area MT are precisely predicted by the statistical prior expectations extracted from psychophysical data. As such, our results provide a normative link between perceptual behavior and the neural representation of sensory information in the brain.
Representations of Nature of Science in High School Physics Textbooks
Authors: Ardwiyanti D. , Jumadi J. , Puspitasari H. , Rahayu P.
Published: February 2022

Nature of science (NOS) is a vital component of scientific literacy that refers to the science's epistemology. Students must possess the NOS conception to address socio-scientific issues using the reasoning and justification patterns like scientists. This qualitative research assessed the representation of NOS quantitatively and qualitatively in the grade XII senior high school physics textbooks. The quantitative representation of NOS was described by the percentage of appearance of each element of NOS, while the delivery approach was used to describe NOS qualitatively. The analysis was conducted on two textbooks focused on electromagnetic radiation, special relativity theory, and quantum phenomena chapters. The NOS framework instrument has been conceptually and empirically valid. The results show that the empirical and scientific theories were addressed with the highest percentage of appearance, while the social and cultural embeddedness of science and scientific methods were poorly addressed. All elements of NOS were represented implicitly. The empirical findings of this study are expected to be able to stimulate the improvement of the representation of NOS in science textbooks in Indonesia.
Mapping of Potential Damages Area in Lombok Island Base on Microtremor Data
Authors: Ridwan M. , Yatini Y. , Pramono S.
Published: February 2022

Lombok Island and its surrounding is an area that has a high seismicitys level because it is located in the Eastern Sunda Arc. Tectonically, Lombok Island located between the Indo-Australia plate collision zone with Eurasia in the south and the fult of the backarc Bali-Flores in the north. This researchâ€™s purposed to determine the distribution of vulnerability index and peak ground acceleration value are used to determine the GSS value, so mapping of potential damage areas could be done. The microtremor data taken on 32 observation points distributed in Lombok Island. Microtremor data is analysed using Horizontal to Vertical Spectral Ratio (HVSR) method to get seismic vulnerability index (Kg) and dominant period. Determination of Peak Ground Acceleration (PGA) value using data from the MASE Stasion measurement results based on earthquake events on August 5, 2018. Seismic vulnerability index and peak ground acceleration value are used to determine the GSS value. Determination of potential damage area using analysis of the dominant period, seismic vulnerability indexs and Ground Shear Strain values. The results of this research showed that seismic vulneribility index value in research area is about 0,029 sekon to 1,360 sekon, seismic vulneribility index value is about 0,56 to 189,92 and GSS value is about 2,52 x 10-5 to 8,46 x 10-3. The results show that the light damage dominated in East Lombok Districts, the moderate damage is on Mataram City and it dominated in West Lombok Districts. The heavy damage present in the most parts of West Lombok Districts.
Development of Learning Media for Earthquake Disaster Through Physics Subjects to Improve Problem Solving Ability and Disaster Preparedness
Authors: Rany T D , Mundilarto M
Published: February 2022

Intensity of the earthquake disaster in Indonesia is quite high. The impact in the form of casualties and infrastructure damage was very severe. It is very important to teach disaster preparedness knowledge from an early age, including in the field of education. The learning being taught is still glued to the material that has not linked disaster knowledge. The purpose of this research is to produce learning media for earthquake disasters based on android through proper physics subjects to improve problem solving skills and disaster preparedness. The design of this research is R D using the 4D model. The data collection instruments are in the form of expert validation sheets which include media experts and material experts. The research data were collected through observation sheets, questionnaire sheets, and inferential analysis. The results of the development of android-based disaster learning media met the very feasible criteria of 92.1 for media experts and 94.1 for material experts. The Manova test statistical results were 95% for problem-solving skills and 92.7% for disaster preparedness, so it was concluded that Android-based earthquake disaster learning media were used effectively to enhance problem solving skills and disaster preparedness.
Development and internal validation of a predictive model for the estimation of pheochromocytoma recurrence risk after radical surgery
Authors: Parasiliti-Caprino Mirko , Bioletto Fabio , Lopez Chiara , Maletta Francesca , Caputo Marina , Gasco Valentina , La Grotta Antonio , Limone Paolo , Borretta Giorgio , Volante Marco , Papotti Mauro , Terzolo Massimo , Morino Mario , Pasini Barbara , Veglio Franco , Ghigo Ezio , Arvat Emanuela , Maccario Mauro
Published: February 2022

Objective

Various features have been identified as predictors of relapse after complete resection of pheochromocytoma, but a comprehensive multivariable model for recurrence risk prediction is lacking. The aim of this study was to develop and internally validate an integrated predictive model for post-surgical recurrence of pheochromocytoma.

Methods

The present research retrospectively enrolled 177 patients affected by pheochromocytoma and submitted to radical surgery from 1990 to 2016, in nine referral centers for adrenal diseases. Cox regression analysis was adopted for model development, and a bootstrapping procedure was used for internal validation.

Results

Variables independently associated with recurrence were tumor size (hazard ratio (HR): 1.01, 95% CI: 1.00–1.02), positive genetic testing (HR: 5.14, 95% CI: 2.10–12.55), age (HR: 0.97, 95% CI: 0.94–0.99), and Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) (HR: 1.16, 95% CI: 1.04–1.29). The predictive performance of the overall model, evaluated by Somers’ D, was equal to 0.594, and was significantly higher than the ones of any single predictor alone (P  = 0.002 compared to tumor size; P  = 0.004 compared to genetic testing; P  = 0.048 compared to age; P  = 0.006 compared to PASS). Internal validation by bootstrapping techniques estimated an optimistic bias of 6.3%, which reassured about a small tendency towards overfit.

Conclusions

We proposed a multivariable model for the prediction of post-surgical recurrence of pheochromocytoma, derived by the integration of genetic, histopathological, and clinical data. This predictive tool may be of value for a comprehensive tailoring of post-surgical follow-up in radically operated pheochromocytoma patients.
Progerin mislocalizes myocardin-related transcription factor in Hutchinson–Guilford Progeria syndrome
Authors: von Kleeck Ryan , Castagnino Paola , Assoian Richard K
Published: February 2022

Hutchinson–Guilford Progeria syndrome (HGPS) is a rare genetic disease of premature aging and early death due to cardiovascular disease. The arteries of HGPS children and mice are pathologically stiff, and HGPS mice also display reduced arterial contractility. We recently showed that reduced contractility is an early event in HGPS and linked to an aberrantly low expression of smooth muscle myosin heavy chain (smMHC). Here, we have explored the basis for reduced smMHC abundance and asked whether it is a direct effect of progerin expression or a longer-term adaptive response. Myh11, the gene encoding for smMHC, is regulated by myocardin-related transcription factors (MRTFs), and we show that HGPS aortas have a reduced MRTF signature. Additionally, smooth muscle cells (SMCs) isolated from HGPS mice display reduced MRTF nuclear localization. Acute progerin expression in WT SMCs phenocopied both the decrease in MRTF nuclear localization and expression of Myh11 seen in HGPS. Interestingly, RNA-mediated depletion of MRTF-A in WT SMCs reproduced the preferential inhibitory effect of progerin on Myh11 mRNA relative to Acta2 mRNA. Our results show that progerin expression acutely disrupts MRTF localization to the nucleus and suggest that the consequent decrease in nuclear coactivator activity can help to explain the reduction in smMHC abundance and SMC contractility seen in HGPS.
Enganchados y ganadores. Deudas e ingresos en la finca cafetalera Perú-París, Chiapas, México (1919-1941)
Authors: Fenner Justus
Published: February 2022

La historiografía posrevolucionaria mexicana acerca de las relaciones laborales en el estado de Chiapas ha dibujado una imagen unilateral al limitar sus interpretaciones a una visión simplista entre explotador y explotado. Esta actitud reduccionista ha negado la diversidad regional en lo geográfico y poblacional igual que ha desconocido los cambios y avances –impulsados por las necesidades del mercado internacional– sucedidos desde finales del siglo XIX, específicamente en las relaciones laborales entre fincas cafetaleras y población indígena. El análisis de la documentación interna de la finca Perú-París pretende abrir más el panorama historiográfico con una visión diferenciada de la realidad laboral en la primera mitad del siglo XX en Chiapas.
Nacionalidad y nacionalismo en el Chiapas posrevolucionario: el «problema demográfico» en Mariscal y Soconusco (1930-1944)
Authors: Gordillo Ballinas Fernando De Jesús
Published: February 2022

La década de 1930 marcó el inicio del reparto agrario en Chiapas, hecho que visibilizó una compleja realidad demográfica en la zona fronteriza con Guatemala. Por un lado existía una importante presencia de trabajadores guatemaltecos, y, por otra parte, muchos pobladores nacidos en la región no contaban con documentos para comprobar su nacionalidad. Para determinar quiénes eran sujetos al reparto de tierras, el Estado mexicano se enfrentó a la monumental tarea de regularizar la nacionalidad de miles de habitantes de aquella región, lo que dio paso a importantes discusiones respecto a lo que significaba ser mexicano en la frontera sur. En el presente artículo se analiza el, así llamado por las autoridades, «problema demográfico», así como los conflictos agrarios, laborales y políticos derivados de dicha situación.
Una insospechada crisis: El gobierno de Rodrigo Carazo Odio y su ambivalente compromiso con la reforma «neoliberal» (1978-1982). Primera parte
Authors: Marchena Sanabria Jorge
Published: February 2022

This article analyzes the contradictory responses that the Carazo Odio administration tried to promote to mitigate the economic crisis of the early 1980s. The objective is to provide a partial reconstruction of the process: how the government defined the crisis or its misunderstanding of it, the insistence on the rhetoric of sovereignty in the face of external financial entities, problems of monetary liquidity, clashes between political factions, among others. It is an approach to the internal dynamics of Costa Rican politics, emphasizing its contradictions between democratization and secrecy. For the preparation of the text, documents from the National Archives from the period 1978-1982 were used, especially from the Presidency Series and Proceedings of the Governing Council.
Enseñar historia mediante las redes sociales y enseñar sobre redes sociales mediante la historia: los alcances de las redes sociales en la enseñanza de la historia
Authors: Gamboa Fallas Marisol
Published: February 2022

The following article was initially presented in the Central American History Congress as part of the History Teaching section. This article describes the use of social media in History Teaching, as a way to include educational technology in this discipline, with the objective of fortify different abilities in students that contribute in their historical thinking and technological competences. These intentions are built in the frame of the Ministry of Public Education of Costa Rica that promotes a new citizenship that involves the development of a digital citizenship. In the context of an Ancient History course, the impact of using social media as part of the didactic is analyzed through a structured observation and several interviews to students. As part of the conclusions, is possible to affirm that using social media allows to fortify abilities as communication, creative thinking and information management. Also, social media is an ideal space to exercise digital citizenship and offer a path to divulgate and strengthen their knowledge.
Una propuesta de mejora curricular desde la perspectiva del pensamiento histórico y crítico para la enseñanza de la historia en El Salvador
Authors: Montoya José , Flores María Julia
Published: February 2022

The purpose of this paper is to present a theoretical and methodological proposal to foster the debate and to support reflection for the teaching of history in the national curriculum of El Salvador. To accomplish this, it is first identified how the teaching of history is incorporated into the curriculum of Social Studies from the first cycle of basic education up to high school. Secondly, the importance of working on historical awareness is developed through a theoretical proposal that includes the interrelation of a historical narrative, the dimensions of historical thought and critical thinking, as well as a potential methodological link with the approach of competency-based education.
Optimal harvesting in a unidirectional consumer–resource mutualisms system with size structure in the consumer
Authors: Liu Rong , Liu Guirong
Published: February 2022

This paper considers the optimal harvesting problem for a size-structured model of unidirectional consumer–resource mutualisms in which the consumer species has both positive and negative effects on the resource species, while the resource has only a positive effect on the consumer. First, we show the existence of a unique nonnegative solution of the system and give the continuous dependence of solutions on the control variable. Next, the adjoint system is derived, which is necessary for optimality and the existence of a unique optimal policy. Then necessary conditions for optimality are established via the normal cone and adjoint system. Moreover, the existence of a unique optimal strategy is proved via Ekeland’s variational principle and fixed-point reasoning in convex analysis. Finally, we use numerical simulations to verify the main results and find other dynamic properties of the system.
Fortalecidos en la adversidad
Authors: Olivetto Roberto
Published: February 2022

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Implementation of an Inpatient Reproductive Health Screening Consult Service
Authors: Goldstein Rachel L. , Keppler Hannah , Pineda Noelle , Weng Yingjie , Carlson Jennifer L.
Published: February 2022

OBJECTIVES

Reproductive health is an important issue in the care of adolescents and young adults (AYA). Unfortunately, many AYAs, particularly those with chronic medical conditions, may not regularly access primary care to address these issues. This study evaluates the impact of an inpatient reproductive health consult service on reproductive health care.

METHODS

A reproductive health-focused screening consult service was initiated in June 2017 at an academic teaching hospital. Patients aged 15 to 26 admitted to pediatric ward teams were eligible for screening. A retrospective chart review was conducted from December 2016 to June 2019 to determine the effect of the consult service on the primary outcome, documentation of a psychosocial assessment, and reproductive health concerns.

RESULTS

Nine hundred twenty-nine encounters were analyzed (345 preintervention and 584 during intervention), representing 675 patients. The proportion of encounters with a documented psychosocial assessment increased from 14.8% to 41.3% during the intervention (P < .001); a reproductive health screening consult was responsible for 37.3% (109 of 292) of the documented assessments. There were high self-reported rates of sexual activity (38%), substance use (47%), and mood concerns (48%) among hospitalized AYA; all behaviors were documented at statistically significant increased frequencies (P < .001) during the intervention compared with preintervention.

CONCLUSIONS

Initiation of an inpatient reproductive health screening consult service led to increased documentation of psychosocial assessments, including increased documentation of sexual health history and other risk factors. With improved screening of reproductive and psychosocial needs, targeted interventions can meet underrecognized needs among hospitalized AYA.
Thermal time in nitrogen and boron application on irrigated Mombaça grass “Guinea grass”
Authors: Jesus Fernanda Lamede Ferreira de , Sanches Arthur Carniato , Souza Débora Pantojo de , Mendonça Fernando Campos , Silva Jhon Lennon Bezerra da , Pacheco Adriano Bicioni , Lisboa Cristiane Fernandes , Costa Monalisa Soares
Published: February 2022

This study aims to evaluate the correlation among growing degree-days (GDD), canopy height (CH), and leaf area index (LAI) for Guinea grass irrigated, considering the different combinations of the nitrogen and boron rates and cycles of regrowth. The experiment was carried out from August/2017 to August/2018 in a field experiment, and the climate of the region is classified as subtropical. A randomized block design arranged in a factorial scheme (4x3x11) with four replications was used. The treatment was (i) boron fertilization: 0, 1, and 2 kg ha-1; and (ii) nitrogen fertilization: 250, 500, 750, and 1,000 kg ha-1 distributing to 11 growth/cutting cycles. We observed the high correlation between GDD and the parameters evaluated of CH and LAI. The nitrogen results showed a low influence on canopy height and the leaf area index, and boron results did not influence these parameters.
Potential synergy between natural gas production and offshore wind power generation: a case study in northeast Brazil
Authors: Wechi Benedet Gabriela , Parga de Paiva Norões Higuel , Dutra de Andrade José Joaquim
Published: February 2022

Offshore wind energy production is non-existent in Brazil, although is currently considered in the country's expansion plans. New and promising oil and gas fields have recently been discovered in the Sergipe and Alagoas basin, corresponding to one third of current Brazilian production. This work analyzes the technical and economic viability of an Offshore Wind Farm to supply the energy demand of a Floating Liquified Natural Gas proposed to be used in those fields. The resulting estimated cost of capital and levelized cost of energy were in line with international values. However, the project proved to be unfeasible due to the high cost for its size and the low average price of energy generation. Nonetheless, the synergy between the oil and gas sector and offshore wind may include benefits such as the reduction of greenhouse gas emissions within the sector itself, making the non-renewable resource available for more noble use.
Isolation and characterization of filamentous fungi from wood and soil samples of “La Lorena”, Sonsón, Antioquia (Colombia), natural reserve
Authors: Montoya-Castrillón Manuela , Serna-Vasco Kelly Johana , Pinilla Laura , Quiceno-Rico Juan Manuel , Cardona-Bermúdez Liliana María , Osorio Echavarría Juliana
Published: February 2022

Fungi, with all their biological and enzymatic qualities, could have great potential being implemented in industrial processes. In this study, filamentous fungi from Sonsón-Antioquia region were isolated and characterized. A morphological characterization was carried out using taxonomic keys and additionally a biochemical characterization qualitatively evaluated the amylolytic, cellulolytic, lipolytic, proteolytic, catalase, peroxidase, and laccase capacity of the strains. Furthermore, isolated fungi were molecularly identified using the LSU region of the rDNA (28S). Among the strains identified, Trichoderma sp., Penicillium sp., Mucor sp. Aspergillus sp. and Lecythophora sp. genera were found and it was observed that the analyzed fungi present at least one of the seven enzymatic activities evaluated and some genera such as Trichoderma sp. and Aspergillus sp. present even six of them. Therefore, the isolated strains show desirable characteristics in food, paper, cosmetic, and textile industries, and in areas such as bioremediation and biological control.
Pressure and Pressure Derivative Interpretation of a Well in a Completed-Perforated Multilayer Reservoir with Crossflow
Authors: Escobar Freddy Humberto , Jafet Navia José , Suescún-Diaz Daniel
Published: February 2022

Several models have been introduced for the characterization of multilayer reservoirs. However, some have failed to provide results when the skin factor of the layers is negative. Therefore, in this work, a model applying the concept of the maximum effective hole diameter has been used to simulate pressure tests in multilayer reservoirs. The pressure behavior of such systems is similar to that of naturally fractured double porosity reservoirs. Then, using the unique features of the log–log plot of pressure and pressure derivative versus time, some expressions have been developed to characterize the reservoir. The equations are satisfactorily tested on three field examples.
Matías Romero Avendaño y la producción de café en Oaxaca, México a finales del siglo XIX
Authors: Morales Becerra Israel , Mondragón Emmanuel Anguiano
Published: February 2022

La investigación se encuentra sustentada en las Memorias de Gobierno disponibles en el Archivo General del Poder Ejecutivo del Estado de Oaxaca. Documentamos el impulso que tuvo la producción de café a través de las iniciativas de Matías Romero Avendaño a finales del siglo diecinueve. Funcionario público y empresario cafeticultor oaxaqueño que plasmó su experiencia en diversos textos. Encontramos que esta actividad agrícola tuvo un impacto positivo en la economía de Oaxaca: la tasa media de crecimiento de la producción de café, medida en quintales, para la década de 1890 fue de 35.3% y para el mismo periodo, el valor de la producción de café creció a una tasa promedio de 24.72%.
Fabrication of magnetic ordered mesoporous carbon for quantitative analysis of acidic phytohormones in mushroom samples prior to their determination by ultra-high-performance liquid chromatography–tandem mass spectrometry
Authors: Zhang Qianchun , Chen Yan , Yang Yanqun , Liu Yulan , Wen Ming , Wang Xingyi
Published: February 2022

A novel method was established for analysing trace four acidic phytohormones, namely, indole-3-acetic acid, 3-indolebutyric acid, abscisic acid, and 1-naphthylacetic acid, using magnetic ordered mesoporous carbon (MOMC). MOMC was facilely synthesised via self-assembly strategy with a direct carbonisation process. The properties of MOMC were characterised using various instruments. MOMC exhibited excellent adsorption capacity towards the analytes. Various critical parameters which may influence the enrichment efﬁciency were evaluated, including amount of MOMC, extraction conditions, and desorption conditions. An efficient method based on MOMC magnetic solid-phase extraction coupled with ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) was developed to analyse the trace four acidic phytohormones, with good correlation coefﬁcients (R2 = 0.9965–0.9998) and low limits of detection (0.13–9.7 ng L−1, S/N = 3). Trace acidic phytohormones in Agaricus bisporus and Hypsizygus marmoreus samples were determined with satisfactory recoveries (91.8–108%) and reproducibility (2.6–6.3%). The features indicated that MOMC provides an efficient platform for mushroom sampling; the developed method is convenient, promising, and sensitive for the detection of trace phytohormones in complicated mushroom samples.
Discrepancy of PCR and serologic test on genital herpes: a case report
Authors: Fadhilla Jhauharina Rizki
Published: February 2022

Background: Laboratory investigation for genital herpes (GH) includes serologic tests and polymerase chain reaction (PCR) with different sensitivity and specificity; occasionally, the results are not conclusive. Clinical symptoms are often atypical. We report a case of GH in HIV-infected patients with a non-reactive serologic test but positive PCR.Case Description: A 29-years old HIV-positive man presented with multiple painful shallow ulcers with pus on his penis in the last five days. PCR examination showed a positive result, whereas anti-HSV 1 IgM, anti-HSV 2 IgM, anti-HSV 2 IgG, VDRL, and TPHA were negative. The anti-HSV- 1 IgG result was reactive with a CD4 value of 122 cells/μL. The patient was given Acyclovir 3x400 mg for ten days and Co-amoxiclav 3x625 mg for seven days. Significant improvement was obtained, and the pain subsided.Conclusion: Clinical features of GH in infected HIV patients are often atypical and resemble other genital ulcers, thus requiring additional investigations. The serologic test may sometimes present a false negative, whereas PCR is much more sensitive and specific, nearing 100%. In patients with HIV infection, GH diagnosis at an early stage can shorten the course of the disease and prevent complications.