bluuebunny/crossref_metadata_2025 huggingface dataset:
Sarcopenia, sarcopenic obesity and osteoarthritis
Authors: Dedukh Ninel , Zaverukha Nataliia , Bystrytska Maryna , Yakovenchuk Nataliya
Published: November 2021

Sarcopenia is considered an important geriatric syndrome, the manifestations of which lead to impaired quality of life and increased mortality. Sarcopenia is a disease associated with decreased muscle mass and strength. Sarcopenic obesity is manifested by an increase in subcutaneous or visceral fat, fatty degeneration of muscles, and is also accompanied by impaired muscle function. After the age of 40, an average of 8 % loss of muscle mass is noted, and by the age of 80 this value can reach 50 %. The review examined the relationship between sarcopenia, sarcopenic obesity, and osteoarthritis (OA).Many exogenous and endogenous factors influence the development and course of OA. Based on the study of mechanisms of cellular and molecular profiles, the specific features for these frequently coexisting pathologies have been identified. The review presents the molecular mechanisms in the development of sarcopenia, sarcopenic obesity and osteoarthritis. Increased fat mass is manifested by increased adipogenesis, expression of inflammatory molecules (leptin, adiponectin, interleukin-1 (IL-1), IL-1b, IL-6 and tumor necrosis factor α) that contribute to chronic low-grade systemic inflammationand negatively affect muscle and joint quality. The relationship between elevated levels of myostatin and muscle weakness as well as myostatin  accumulation in synovial fluid and severity of osteoarthritis was considered. Some common mechanisms in the development of sarcopenia and OA were noted: the influence of oxidative stress, systemic chronic inflammation, and disruption of the signaling pathway of bone morphogenetic proteins. Based on the analysis of associations between sarcopenia, sarcopenic obesity, and OA, population-based studies have revealed a high prevalence of knee OA with an increased risk among men with sarcopenic obesity. Women with sarcopenia and sarcopenic obesity had a high risk of knee OA in both groups. The review reviewed the prevention and treatment of the combined pathology, in particular the effect of sarcopenia on the results of total joint а rthroplasty in patients with OA. In general, sarcopenia, sarcopenic obesity, and OA can be considered as concomitant age-associated diseases that jointly affect quality of life and life expectancy.
The Value of Work-Related Uncertainty: Changes from Demands on Certainty to Finding Ways of Living in Uncertainty
Authors: Müller Michal
Published: November 2021

Given the negative consequences that excessive confrontation with uncertainty can have, its positive dimension is often forgotten. The aim of this article is to show that the uncertainty associated with work, working conditions and the context in which working relationships are formed can be considered as a positive value. This will be shown through four themes. The first theme concerns the economic system. It is important to show that a certain degree of insecurity is necessary not only for individual freedom in society, but also for society as a whole, as there is a relationship between economic and political freedom. The second theme concerns entrepreneurship. In this respect, the article reminds us that uncertainty is a prerequisite for entrepreneurial activity. The third area deals with employment. Uncertainty and the life experience associated with it is an opportunity for personal development and the search for innovative ways of coping and solving problems, moreover, it is related to a sense of freedom. The fourth theme deals with the positive role of uncertainty in the context of the current crisis caused by the COVID-19 pandemic. However, this positive value will only emerge if human health is protected.
Autoavaliação da memória de jovens universitários
Authors: Melo Crislaynne Kelly Carvalho de , Roseno Antônio Vitor da Silva , Silva Arthur José Lopes da , Pessoa Tayná Fernandes , Santana Gabrielly Alves de , Santiago Libini Evelyn de Souza , Montenegro Déborah Lúcia Feitosa , Almeida Larissa Nadjara , Lima Ivonaldo Leidson Barbosa
Published: November 2021

RESUMO Objetivo analisar a autoavaliação da memória de jovens universitários. Métodos trata-se de um estudo observacional, transversal, de caráter analítico, com abordagem quantitativa. Participaram 519 estudantes, matriculados regularmente em instituições de ensino superior, com média de idade de 22,9 anos (±5,5), sendo 408 mulheres e 111 homens. Os instrumentos utilizados foram o Questionário de Memória Prospectiva e Retrospectiva - QMPR (Prospective and Retrospective Memory Questionnaire - PRMQ-10) e um questionário com informações sociodemográficas e com queixas de memória relacionadas às atividades acadêmicas. Os dados foram analisados quantitativamente, de forma descritiva e inferencial, com uso do teste Qui-quadrado, considerando o valor de p<5%. Resultados os jovens universitários relataram dificuldades frequentes de memória, em especial na prospectiva e de curto prazo. Foi visto que 46,6% dos participantes apresentaram queixas de memória e 62,8% referiram acreditar que a rotina na universidade pode provocar aumento nas falhas de memória. Na autoavaliação, verificou-se que 47,7% mencionaram dificuldades na memória prospectiva e de curto prazo e, em relação à rotina acadêmica dos universitários, 46,4% relataram dificuldades na memória retrospectiva. Conclusão há associação entre a presença de queixa e os dados da autoavaliação da memória.
COMO O RACISMO ESTRUTURAL IMPEDE A IMPLEMENTAÇÃO DA ERER NO ENSINO DE QUÍMICA
Authors: Alves Mendes Carla Cristina , Costa da Silva Gustavo Henrique , Dos Reis Mariana Gabriele , Quintino Amauro Nicea
Published: November 2021

Considerando que as escolhas curriculares se apresentam em consonância com a história singular e caucasiana, não contemplando a diversidade dos corpos presentes nos espaços escolares, este artigo busca evidenciar como o racismo estrutural impede a implementação da Educação para as Relações Étnico-Raciais no Ensino de Química (EREREQ). Para tanto, estabelecemos uma relação entre o racismo estrutural e o ensino de Ciências/Química, consubstanciada por entrevistas feitas com seis educadores/as de Química que lecionam para alunos do Ensino Médio de escolas públicas e particulares do estado de Minas Gerais, a partir destas construímos significados para aprimorar a compreensão de como o racismo estrutural atua em seu caráter impeditivo para a realização de atividades pedagógicas intencionalmente organizadas. Trata-se, portanto, de uma pesquisa qualitativa que, por meio de análise de conteúdo, discutiu as respostas dos participantes com respaldo na biografia específica da EREREQ. Nesse sentido, as entrevistas e suas respectivas análises nos permitiram concluir que há múltiplos lugares de origem da manifestação da hierarquização e da desigualdade racial. Constatamos, ainda, que a resistência à efetivação da EREREQ se encontra não somente no comportamento dos estudantes e das famílias, mas também na postura de professores e professoras, que transferem a responsabilidade para as instituições de ensino ou para o currículo.
COVID-19 PANDEMİSİNİN FİNANSAL PİYASALARA ETKİSİ: GELİŞMİŞ ÜLKELER ÜZERİNE BİR ANALİZ
Authors: EREN Binali Selman , KANDİL GOKER Ilkut Elif , KARACA Süleyman Serdar
Published: October 2021

Bu çalışma, COVID-19’un Dünya Sağlık Örgütü tarafından 11 Mart 2020 tarihinde pandemi ilan edilmesi karşısında MSCI ACWI (Morgan Stanley Capital International-all-country world) endeksinde yer alan önemli borsa endekslerinin tepkisini ölçmeyi amaçlamaktadır. Olay çalışması yöntemi kullanılarak 22 gelişmiş ülkeye ait öncü borsa endeks getirilerinin olay öncesi, olay günü ve olay sonrası tepkileri tespit edilmiştir. Olay çalışması yöntemi piyasaların yarı güçlü formda etkin olduğunu varsaymaktadır. Yarı güçlü formda etkin bir piyasa, finansal varlıkların fiyatlarının söz konusu varlığın tüm halka açık bilgilerinin verildiği bir piyasayı karakterize etmektedir. Bu tür piyasalarda finansal varlıklar geçmiş bilgilerin yanı sıra kamuoyuna açıklanan ek bilgileri de içermektedir. Elde edilen bulgulara göre tüm olay öncesi pencerelerde, borsa endekslerinin tamamında yüksek kayıpların olduğu, olay günü Amerika Kıtası ülkelerinde pandemi ilanına borsaların güçlü yönde negatif bir tepki verdiği gözlenmiştir. Yine Avrupa ve Asya piyasalarında yüksek ortalama anormal getirilerin gözlemlenmediği, olay sonrası dönemde ise olay tarihinden 5 gün (0…+5) sonraki dönemde piyasaların panik havası içinde olduğu ancak daha uzun olay pencerelerinde piyasaların toparlanma yaşadığı tespit edilmiştir. Bölgesel düzeyde bakıldığında vaka ve ölüm sayısı daha düşük olan Asya ülkelerinin vaka ve ölüm sayısı yüksek olan Avrupa ve Amerika Kıtası ülkelerine göre daha az getiri kaybı yaşadığı sonucuna ulaşılmıştır. Çalışmanın sonuçları, gelişmiş ülkelerin borsalarının COVID-19’un küresel salgın ilan edildiği (11 Mart 2020) tarihte ve tarih etrafındaki anormal getiriler göz önüne alındığında piyasaların yarı güçlü formda etkin olmadığını destekler niteliktedir.
ICMS Ecológico
Authors: Silva Matheus Maramaldo Andrade , Bezerra Maria do Carmo Lima
Published: October 2021

The Urban Green Areas System (UGAS) performs relevant functions for the quality of life by making cities healthier, which has become even more necessary in the current period of pandemic. However, even with these benefits, the practice of urban management indicates difficulties not only in the implementation, but also in the maintenance of the UGAS. One of the aspects that may explain the challenge of implementing and maintaining green areas in cities is the absence of regulatory instruments and financial incentives that support this system. In this line, in order to contribute to this discussion, one of the instruments that proved to be effective in environmental management will be studied, in this case for the creation and implementation of Conservation Units: the “ICMS Ecológico”. This article will study the characteristics of the UGAS associated with ecological and urban functions; the logic of adopting the “ICMS Ecológico” and will seek to define criteria that can be used for the implementation of a UGAS that prioritizes ecosystem thinking associated with the function of urban health. We started with the discussion about the mechanisms for adopting the “ICMS Ecológico” and followed the analysis of the standards established in the states for its application. As a result, it was found that there are similarities that can be applied to an implementation in the urban green area systems, which allowed the recommendation of criteria that can be used as a reference for the application of the “ICMS Ecológico” to support the UGAS and the promotion of healthier cities.
The effects of social isolation and the COVID-19 pandemic on air quality around the world
Authors: Duarte Renata Lopes , Silva Cláudio Paiva , Rocha Cézar Henrique Barra
Published: October 2021

In December 2019, a new virus variant was discovered in China, belonging to the coronavirus family, whose associated respiratory syndrome became known as COVID-19. Due to the ease of transmission, lethality and lack of knowledge about this new disease, several countries chose to adopt measures of social distancing, in addition to restrictions on travel and the performance of activities considered non-essential. Thus, the present study aimed to carry out a bibliographic survey about the main effects of social isolation on air quality, in some regions around the world, through consultation of scientific articles, national and international research institutes, as well such as satellite imagery. The results showed that the effects of these measurements were observed on air quality in different parts of the world, with a reduction in the levels of some of the main air pollutants, such as NO2, CO2, CO and particulate matter. In contrast, some studies showed that the concentration of O3 increased in certain regions. It was possible to conclude that the improvements observed were temporary, as they did not result from structural measures, but from transitory situations; and that the adoption of public policies to restrict the emission of pollutants is essential to reduce the incidence and aggravation of associated respiratory diseases, avoiding the overload of health systems, especially in the current pandemic scenario.
COVID-19 Pandemic
Authors: Silva Márcia Regina Farias da , Silva Carlos Aldemir Farias da , Dutra Maria da Conceição Farias da Silva Gurgel
Published: October 2021

In contemporary society, the advancement of the new coronavirus (SAS-CoV-2) has made clear the relationships between society's actions and their consequences, both in the spread of the disease and, in the environmental issue, in the imbalance of ecosystems. In this sense, this study seeks to present a reflection on the relationship between modern science, the environment, and the health crisis of Covid-19, having as theoretical basis the studies of Ulrich Beck on risk society in the context of globalization. As a methodological procedure, a bibliography and documentary research were carried out. The study found that the current model of society can lead humanity to catastrophes at a global level, without the possibility of calculating the risk, since environmental problems are beyond the control of society and present many uncertainties, especially in the post-pandemic.
Protocol: Comparative efficacy of sedation or analgesia methods for reduction of anterior shoulder dislocation: a systematic review and network meta-analysis v3
Authors: Hayashi Minoru , Kano Kenichi , Kuroda Naoto , Yamamoto Norio , Shiroshita Akihiro , Kataoka Yuki
Published: October 2021

The objectives are as follows: To review systematically comparative efficacy of sedation or analgesia methods for reduction of anterior shoulder dislocation.
Roma Hukukunda Çiftçi Yasaları Üzerine Bir Değerlendirme
Authors: KOÇAK Talat
Published: October 2021

İnsanlığın tarım toplumuna geçişi İÖ 10.000-6.000 yıllar arasında Neolitik Çağ’da olmuştur. Bu dönemde tarıma geçilmesinin bir sonucu olarak suya yakın, tarıma elverişli yerlerde sabit köy yerleşmeleri görülmeye başlanmıştır. İnsanların göçebe yaşam tarzından yeni bir düzene geçmesinden dolayı bazı araştırmacılar bu olayı “Neolitik Devrim” olarak adlandırılmıştır. Tarımdaki bu ilerlemenin bir sonucu olarak devam eden süreçte hukuk alanında da çiftçilikle ilgili kanunlar meydana getirilmiştir. Çiftçilikle ilgili ilk yasa örneklerini Mezopotamya ve Anadolu Kanunlarında görmekteyiz.

Roma başlangıçta bir tarım toplumudur. Dünya hukuk tarihine önemli katkılar sunan bu medeniyette çiftçilerle ilgili kanun maddeleri bir hayli yer tutar. Bu yasalar Theodosianus ve Iustinianus hukuk külliyatında toplanarak, geç imparatorluk dönemi uygulamaları kayıt altına alınmıştır. Her ne kadar Digesta 6. yüzyılda oluşturulmuşsa da bu yüzyıla ait kanunların sayısı oldukça azdır. Kanunların geneli 2. ve 5. yüzyıllardaki hukukçuların çalışmalarını içermektedir. Çiftçi Yasaları Geç Antik Çağ’ın son hukuksal metni olan ve Ecloga adı verilen kanunların, ekler kısmında da kendine yer bulacaktır. Yasalar çiftçilerin sadece tarla, hasat ve sınır problemleriyle ilgili değildir. Vergi, büyük ve küçükbaş hayvanlar, kümes hayvanları, üzüm yetiştiriciliği, değirmenler ve tarım aletleri ile ilgili çiftçiler arasında yaşanan sorunlara çözümler sunmaktadır.
MAIN STAGES AND REGULARITIES OF COAST FORMATION OF LARGE PLAIN RESERVOIRS
Authors: Dubnyak S.S.
Published: November 2021

The main stages of the reservoir coast formation and their typological characteristics are considered on the base of the analysis of long-term monitoring studies of the Dnieper reservoirs coast dynamics, as well as generalization of published materials on other large plain reservoirs. It is shown that the common scheme of periodization of the shoreline development manifested itself only in the two stages: abrasion and abrasion-accumulative leveling, and therefore it is premature to claim the general stabilization of the coast formation process. The conventionality of the dynamic equilibrium stage for the coast of reservoirs and the growing role of coastal currents and associated sediment flows and dynamic coast systems are noted. The current state of the coasts of large plain reservoirs is estimated as the beginning of the stabilization phase on the coasts with sufficient sand materials. On the coasts composed of loess, clay or loams the processes of intensive transformation are continued. The analysis of the direction of development of the coastal zone showed three stages of change of shore profile and plan: intensive formation, stabilization and the final stage of attenuation according to the leading factors. Active accumulation means the transition to the stage of abrasion-accumulative leveling, and the emergence of dynamic coast systems and activation of coastal sediment flows means the transition to the dismemberment of the shoreline by accumulative forms. The main regularities of development of coast formation processes – heredity, direction, inertia and variability are analyzed. The heredity means that the geographical and geological conditions which developed before the filling of the reservoir are played the leading role in these processes. The direction of development is associated with an increase of the erosion base and its consequence – the leveling of the coastal zone relief. The orientation of the general process of coast formation to achieve a state of dynamic equilibrium includes stages of inertia and variability. Inertial states are the certain periods when a certain set of factors and conditions and corresponding to them type of coast prevails. Variability is a change in factors and conditions, as a result of which new types of shores or fluctuations in the characteristics of the coastal zone (movement of shoals and dynamic coastal systems, seasonal changes in shore profiles) are formed.
History of the research laboratory (medicinal and environmental toxicology) of the Military medical academy named after S.M. Kirov
Authors: Sofronov Genrikh A. , Murzina Elena V. , Denisov Alexey V. , Veselova Olga M. , Krylova Tat'yana G.
Published: November 2021

This paper presents the history of the formation of the Research Department of the Experimental Medicine of the Research Center of the Military Medical Academy named after S.M. Kirov. The department is the only division of the academy that conducts experiments on animal models and field tests using laboratory animals in the interests of the Armed Forces of the Russian Federation. The paper also presents the main scientific achievements and development prospects of one of the three laboratories of the department Research Laboratory of Medicinal and Environmental Toxicology. In the direction of drug toxicology, the laboratory staff worked for 15 years in cooperation with the Scientific Center of the Russian Academy of Sciences (Pushchino) on the problems of perfluorocarbon-based blood substitutes. The results of the study helped deepen the understanding of the mechanisms of the physiological activity of perfluorocarbon emulsions and the expansion of the areas of clinical application of perftoran. The ecotoxicological direction of scientific research is represented by two large-scale cycles of scientific studies. The first was devoted to the medical support of oil refining to increase the protection of personnel who have been professionally exposed to toxic chemicals from the damage caused by chemical accidents. The second area of environmental research, which has been significantly updated in recent years, is devoted to the study of remote environmental and biomedical consequences of the use of chemical weapons by the US Army in the period from 1966 to 1972 in Vietnam. In recent years, the laboratory has focused on problems related to the search and development of new radiation countermeasure agents including biotechnological products and their compositions. Studies are also being conducted to improve the complex therapy of patients with sepsis, in which methods of extracorporeal blood purification are used in the treatment. These works are relevant for military and civilian health care and are performed in cooperation with the departments of the academy and several leading research organizations in St. Petersburg.
Pathophysiological bases of maladjustment formation in high mountains and polar zones
Authors: Kim Aleksey E. , Shustov Evgeniy B. , Lemeshchenko Aleksey V. , Tsygan Vasily N.
Published: November 2021

The pathophysiological features of the development of maladjustment under mountain-cold conditions as a manifestation of the syndrome of mutual burdening are considered. In this study, contents of various literary sources, characterizing a persons resistance to the effects of a complex of factors under high mountains and polar zones conditions, were analyzed. With the simultaneous exposure to hypoxia and hypothermia from a pathophysiological point of view, intersecting links of terminological paths, often having diametrically opposite dynamics of changes in the characterized concepts, will be significant. Thus, in the terminological mitochondrial pathway of energy metabolism, uncoupling proteins are present, which, to increase the resistance to hypothermia, should be activated to switch the energy metabolism to predominantly use fatty acids. However, hypoxic conditions should be suppressed to maintain the level of adenosine triphosphate acid available for cells. In the terminological tract of compensatory reactions in response to hypoxemia, the volume of pulmonary ventilation is released, which must increase to improve tolerance to hypoxia, which, under mountain-cold conditions, increased heat loss and promote the deterioration of the condition, i.e., tolerance to low temperatures. Under hypoxic and hypothermic conditions, a synergistic interaction can form, which can be manifested by the development of a syndrome of mutual burdening, which will result in a significant decrease in the functional capabilities of the body, result, and productivity. Maladjustment to mountain cold, with maximum probability, will manifest as disorders of the central nervous system, decreased physical performance, depletion of the functional and regulatory reserves of the body, functional immunodeficiency, decreased regenerative potential, and development of endogenous intoxication. With a high degree of probability, a significant synergistic interaction of hypoxia and hypothermia can be found in relation to the indicators of pulmonary ventilation, blood gases (hypercapnia), acidbase balance (gas alkalosis and lactic acidosis), heart rate (tachycardia), blood pressure (hypotension), central venous pressure (increase), blood viscosity (increase) and its coagulability (hypercoagulation), peroxide and free radical oxidation (activation), and protein catabolism (increase). These changes will negatively affect the functional state of specialists performing complex professional tasks in polar latitudes.
Molecular and biological aspects of forecasting the oncological efficiency of cytoreductive surgery in metastatic colon cancer
Authors: Sazonov Aleksey A. , Maistrenko Nicolay A. , Romashchenko Pavel N.
Published: November 2021

Through an immunohistochemical study, the molecular biological properties of adenocarcinoma in patients with stage IV colorectal cancer with synchronous unresectable liver metastases, who underwent cytoreductive interventions for volume removal of the primary tumor, were examined. This study clarified the criteria for selecting patients with stage IV colon cancer with unresectable synchronous metastases in the liver for cytoreductive surgery from the standpoint of the molecular biological properties of the tumor. The prognostic significance of immunohistochemical markers such as the index of proliferative activity of stem cancer cells (ALDH + Ki-67 +) and the receptor for chemokines CXCR4 was established. The level of their expression correlates with the life expectancy of patients who underwent cytoreductive surgery. Thus, the high proliferative activity of cancer stem cells (ALDH + Ki67 + 50%) and the high expression of chemokine receptor (CXCR4 70%) correlate with the rapid disease progression after surgical treatment. A significant inverse relationship was traced between the expression level of the receptor for chemokine CXCR4 as well as the proliferative activity of cancer stem cells and life expectancy of patients with stage IV colon cancer after cytoreductive surgery. The expediency of immunohistochemical studies in patients with metastatic colon cancer has been substantiated. Its implementation provides important information about the potential for tumor aggressiveness, which makes it possible to clarify the indications for performing cytoreductive surgery and improve the results of surgical treatment of this category of patients.
Surgical treatment in patients with chronic pancreatitis in a multidisciplinary hospital
Authors: Aliev Rustam K. , Romashchenko Pavel N. , Maistrenko Nicolay A. , Pryadko Andrey S. , Aliev Arsen K.
Published: November 2021

A rational personalized program of surgical treatment of patients with various clinical and morphological forms of chronic pancreatitis is substantiated, integrating modern diagnostic and minimally invasive technologies. Examination results and treatment of 354 patients with chronic pancreatitis were analyzed. Patients were divided into three groups according to the modified Marseille-Rome Classification of Chronic pancreatitis (1988). Calcifying chronic pancreatitis was detected in 119 patients, obstructive in 81, and inflammatory in 154. Modern methods of diagnosis and treatment of chronic pancreatitis allowed the modification of the classification by allocating subgroups for each disease form. The justified use of the entire range of modern surgical technologies, taking into account the morphological changes of the pancreas, allows the maximum correction of complications of chronic pancreatitis with minimal complications and good quality of life in the long-term. The choice of surgical aid in patients with chronic pancreatitis is established to primarily depend on the form and variant of the disease course. The main criteria for choosing a surgical aid should be the state of the pancreatic ductal system, the degree and nature of changes in its parenchyma, and the presence of a cystic or inflammatory component during the surgical decision making. Important adjustments in the stage of surgical interventions are made due to mechanical jaundice, portal hypertension, decompensated duodenal stenosis, and concomitant somatic pathology in patients. Subgroups of patients with identified main chronic pancreatitis form, according to its modified classification, allows the determination of the surgical intervention volume, type, and access for each specific patient.
Safety in parathyroid surgery: innovation in diagnostic and minimally invasive operations
Authors: Romashchenko Pavel N. , Maistrenko Nikolaj A. , Vshivtsev Dmitry O. , Krivolapov Denis S. , Pryadko Andrey S.
Published: November 2021

The main treatment method of primary and tertiary hyperparathyroidism is surgery. However, surgical interventions on the parathyroid glands can lead to formidable complications such as laryngeal paresis and hypocalcemia. With this background, a comprehensive study examined the effectiveness of modern methods of diagnosis and surgical treatment of hyperparathyroidism to increase the safety level in surgery of the thyroid gland. The results of a comprehensive examination and treatment of 53 patients with hyperparathyroidism who underwent surgery using three methods were analyzed: traditional (n = 18/34); minimally invasive endoscopically assisted (n = 32/60), and endoscopic (transoral) (n = 3/6). Intraoperative neuromonitoring was also performed in all surgical interventions. Parathyroidectomy was performed under parathyroid monitoring for intraoperative topical diagnosis of parathyroid tumors in nine patients. The use of minimally invasive endoscopically assisted access to the parathyroid glands, as an alternative to the traditional approach, indicated that the preoperative potential in the diagnosis of parathyroid disorders. Moreover, intraoperative neuromonitoring and parathyroid monitoring demonstrated efficiency based on the decline in the incidence of specific postoperative complications with a tolerable increase in operative time, maintenance of the average duration of stationary treatment after surgery, and increased safety level of surgical treatment of hyperparathyroidism.
Long-term results of surgical treatment for stage cT1 kidney cancer
Authors: Rakul Sergey A. , Romashchenko Pavel N. , Pozdnyakov Kirill V. , Maistrenko Nikolay A.
Published: November 2021

Studied herein are the long-term results after surgical treatment of stage cT1 kidney cancer. The study includes 278 surgeries for kidney tumors. Partial nephrectomy was performed in 199 (71.6%) cases and radical nephrectomy in 79 (28.4%). Surgeries were performed using the open, laparoscopic, and robotic approaches. Surgical treatment and long-term oncological results were studied. Open approach for partial nephrectomy was used in 2.01% of cases, laparoscopic in 27.64%, and robotic in 70.34%; and radical nephrectomy in 2.53%, 87.34%, and 10.13%, respectively. Incidence postoperative complications after partial and radical nephrectomy were 16.58% and 3.8%, respectively. Сomplications (Clavien Dindo 3) occurred in 11.56% and 3.8% cases, respectively. Positive surgical margin occurred after partial nephrectomy in 1.51%, whereas undetermined for radical nephrectomy. The 5-year disease-free survival for partial and radical nephrectomy was 94.98 1.77% vs. 86.96% 4.11%; 5-year overall survival was 96.2% 1.55% vs. 88.15% 3.96%; 10-year overall survival was 90.82% 4.19% vs. 76.32 6.1%; and 5-year cancer-specific survival was 99.16% 0.84% vs. 94.09% 2.87%, respectively. Our study demonstrates that partial nephrectomy is a safe and effective method for surgical treatment in stage cT1 kidney cancer. A minimally invasive approach is a priority. The nephron-sparring technique demonstrates superior long-term results compared with radical nephrectomy.
Special aspects of intensive care of patients with complicated diverticulosis of the colon
Authors: Shah Boris N. , Abdulaev Magomed A. , Avdeev Aleksey M. , Strukov Egor Yu. , Shchegolev Aleksey V. , Volchkov Vladimir A.
Published: November 2021

This study presented examination and treatment results of 129 patients with bleeding from the lower gastrointestinal tract who were treated at the Alexandrovskaya Hospital of St. Petersburg in the period from 2012 to 2017. Examination and treatment were performed in the intensive care unit following current clinical guidelines, taking into account the identified concomitant diseases. Endoscopic examination of the colon is the main diagnostic method for the pathological processes that caused bleeding from the lower gastrointestinal tract. Conservative therapy has been demonstrated effectiveness, and urgent surgical treatment was not needed. The main drug therapy included antifibrinolytic drugs and fresh-frozen plasma preparations. Continuous parenteral administration of proteolysis inhibitors was mandatory. Intensive therapy included correction of hemodynamic disturbances and respiratory failure and restoration of the volume of the circulating blood and plasma. Such an approach was found to be 90% effective. In patients with diverticular disease, bleeding from the colonic diverticula develops in one-third of cases. However, if additional risk factors are present, their frequency reaches 50%, often causing death. Continuous or recurrent bleeding is an indication of surgery. In our study, the conservative method of stopping bleeding from the colonic diverticula was possible in all cases. In general, the disease correlated with the age of the patients. In 68 (53%) patients, bleeding occurred despite anticoagulant or antiplatelet therapy. Patients with bleeding from colonic diverticula do not require urgent surgical intervention, and these patients may require admission to the intensive care unit. Intensive care should include the provision of antifibrinolytic drugs, proteolysis inhibitors, and fresh-frozen plasma.
Pengaruh Iklan terhadap Perilaku Merokok Siswa: Literature Review
Authors: Hasanah Rofiatul , Gayatri Rara Warih , Ratih Suci Puspita
Published: October 2021

Abstract: The prevalence of adolescent tobacco users in Indonesia continues to increase, while on the other hand the marketing of cigarettes through advertising is still often found. This Literature review aims to find out the results of previous research on the influence of advertising on smoking behavior of junior high school students in Indonesia for the last 10 years. The research method used is literature review by following the flow diagram of the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) as well as the help of Axis Tools as a Critical Appraisal. The result of this literature review, 7 out of 9 articles reviewed stated a significant influence between cigarette advertising and student smoking behavior. The domain of targeted behavior is practice, including the act of trying cigarettes for the first time as well as the formation of perceptions about cigarettes in accordance with the description of the ad. It can be concluded that the influence of exposure to the ads is directly proportional to the smoking behavior of high school students in Indonesia.

Abstrak: Prevalensi pengguna tembakau usia remaja di Indonesia terus meningkat, sedang di sisi lain pemasaran rokok melalui iklan masih sering ditemukan, Literature review ini bertujuan untuk mengetahui hasil penelitian terdahulu mengenai pengaruh iklan terhadap perilaku merokok siswa sekolah menengah pertama di Indonesia selama 10 tahun terakhir. Metode penelitian yang digunakan ialah kajian pustaka dengan mengikuti diagram alir Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) serta bantuan Axis Tools sebagai Critical Appraisal.  Hasil yang didapatkan dari literature review ini, 7 dari 9 artikel yang dikaji menyatakan adanya pengaruh signifikan antara iklan rokok dengan perilaku merokok siswa. Domain perilaku yang disasar ialah praktik, termasuk adanya tindakan mencoba rokok untuk pertama kali serta terbentuknya persepsi mengenai rokok yang sesuai dengan gambaran iklan. Dapat disimpulkan bahwa pengaruh paparan iklan berbanding lurus dengan adanya perilaku merokok siswa sekolah menengah pertama di Indonesia.
Hubungan antara Detraining Selama Pandemi Covid-19 dengan Kemampuan Daya Ledak Otot Tungkai Atlet UKM Karate
Authors: Ningsih Fitria , Andiana Olivia , Abdullah Ahmad
Published: October 2021

Abstract: Karate is one of the most popular martial arts practiced around the world. Karate training puts a great deal of stress on the peripheral joints, and the rotational motion of the spine can greatly affect their mobility. Explosive power is needed in the sport of karate because explosive power is a support in every karate technique movement. Someone who stops exercising for 2-4 weeks will experience a decrease in physiological functions of the body or can be called detraining. The purpose of this study was to determine whether there was a relationship between detraining during the Covid-19 pandemic against the leg muscle explosive power of athletes of Karate UKM State University of Malang. The research is a quantitative correlational study with a causal design. In this research, the sample used is athlete karate State University of Malang as many as 19 people. The data collection method used According to the research, there is a relationship between detraining explosive muscle leg athletes ukm karate Universitas Malang with a p-value is 0.000 less than α is 0,05 and Value correlation coefficient obtained by 0.886. Research concludes that there is a relationship between detraining during the Covid - 19 pandemic on the leg muscle explosive power of SMK karate athletes, State University of Malang.

Abstrak: Karate merupakan salah satu beladiri yang paling populer dipraktikkan di seluruh dunia. Pelatihan karate memberikan tekanan yang besar pada sendi perifer, dan gerakan rotasi tulang belakang dapat sangat mempengaruhi mobilitasnya. Daya ledak sangat dibutuhkan dalam olahraga karate dikarenakan daya ledak merupakan penunjang dalam setiap gerakan teknik karate. Seseorang yang berhenti latihan selama 2-4 minggu akan mengalami penurunan fungsi fisiologis terhadap tubuh atau bisa disebut detraining. Tujuan dari penelitian ini adalah untuk mengetahui apakah terdapat hubungan antara detraining selama pandemic Covid-19 terhadap daya ledak otot tungkai Atlet UKM Karate Universitas Negeri Malang. Penelitian ini merupakan penelitian kuantitatif korelasional dengan desain sebab akibat. Dalam penelitian ini, sampel yang digunakan merupakan atlet karate Universitas Negeri Malang sebanyak 19 orang. Metode pengambilan data menggunakan Berdasarkan hasil penelitian, terdapat hubungan antara detraining dengan daya ledak otot tungkai atlet ukm karate Universitas Negeri Malang dengan p-value sama dengan 0,000 kurang dari α sama dengan 0,05 dan Nilai correlation coefficient yang didapatkan sebesar 0,886. Penelitian ini menyimpulkan bahwa terdapat hubungan antara detraining selama pandemic Covid- 19 terhadap daya ledak otot tungkai atlet ukm karate Universitas Negeri Malang.
Kebugaran Jasmani Peserta Ekstrakurikuler Olahraga di SMA Negeri Kota Malang
Authors: Prayitno Joko , Winarno M. E.
Published: October 2021

Abstract: This study aims to determine the physical fitness of extracurricular participants at SMA Negeri Malang City, East Java. The method used is a survey with a research sample of 57 students participating in extracurricular activities. The data collection instrument used the TKJI test which was analyzed using descriptive analysis. The results showed that the extracurricular participants at SMA Negeri 7 Malang City were as follows: There was 1 student or 1.75 percent in the good category, 25 students or 43.9 percent had physical fitness in the moderate category, and 31 students or 54.4 percent in the poor physical fitness category. The conclusion of this study is that the overall physical fitness of extracurricular participants at SMA Negeri 7 Malang is included in the poor category.

Abstrak: Penelitian ini bertujuan mengetahui kebugaran jasmani peserta ekstrakurikuler di SMA Negeri Kota Malang Jawa Timur. Metode yang digunakan survey dengan sampel penelitian sebanyak 57 orang siswa peserta ekstrakurikuler. Instrumen pengumpul data menggunakan tes TKJI yang dianalisis menggunakan analisis deskriptif. Hasil penelitian menunjukkan peserta ekstrakurikuler di SMA Negeri 7 Kota Malang adalah sebagai berikut: Terdapat 1 siswa atau 1,75 persen dengan kategori baik, 25 siswa atau 43,9 persen memiliki kebugaran jasmani dengan kategori sedang, dan 31 siswa atau 54,4 persen dengan kategori kebugaran jasmani kurang. Kesimpulan penelitian ini secara keseluruhan tingkat kebugaran jasmani peserta ekstrakurikuler olahraga di SMAN 7 Kota Malang tergolong dalam kategori kurang.
Peran Diskusi Suami Istri terhadap Kepatuhan Kunjungan Antenatal Care (ANC)
Authors: Cahyanti Fadhila Tri , Supriyadi Supriyadi , Deniati Ema Novita
Published: October 2021

Abstract: Every marriage must experience various problems that occur especially in the wrong communication between husband and wife. A true communication must be well established, especially during the wife's pregnancy, especially for the husband. The East Java Provincial Health Office stated that the K4 coverage for East Java Province was 91.15 percent. Pamekasan Regency is a Regency in East Java that has less desire for visits to pregnant women's health services is 92,75 percent, while target MSS. This study uses an observational quantitative cross-sectional approach with a sample of 112 married couples determined using the technique Accidental Sampling. Data collection using questionnaires includes two parts, namely husband's discussion and wife's discussion, based on The results show that there is an influence between husband's discussion on ANC visits and there is no influence between wife's discussion on ANC visits with the meaning that there is a role for husband and wife discussions to encourage ANC visits. the health of the wife and fetus is healthy until the delivery is smooth. And improve and develop programs related to the promotion of maternal and child health (MCH).

Abstrak: Setiap pernikahan pasti mengalami berbagai masalah yang terjadi terutama pada komunikasi yang salah antara suami istri. Suatu komunikasi sejatinya harus terjalin dengan baik terutama pada masa kehamilan istri, terutama bagi suami. Dinas Kesehatan Provinsi Jawa Timur menyatakan bahwa cakupan K4 untuk Provinsi Jawa Timur sebesar 91,15. Kabupaten Pamekasan merupakan Kabupaten di Jawa Timur yang mempunyai hasrat kunjungan yang kurang terhadap pelayanan kesehatan ibu hamil adalah 92,75 persen, sedangkan sasaran SPM Penelitian ini menggunakan kuantitatif observasional pendekatan Cross Sectional dengan jumlah sampel 112 pasangan suami istri yang ditentukan dengan menggunakan teknik Accidental Sampling. Pengumpulan data menggunakan penyebaran kuesioner meliputi dua bagian yaitu diskusi suami dan diskus istri, berdasarkan hasil bahwa ada pengaruh antara diskusi suami terhadap kunjungan ANC dan tidak ada pengaruh antara diskusi istri terhadap kunjungan ANC dengan makna ada peran diskusi suami dan istri terhadap mendorong melakukan kunjungan ANC. Dan diharapkan dapat meningkatkan komunikasi dan motivasi kepada sang istri terhadap kepatuhan kunjungan ANC agar kesehatan istri dan janin sehat hingga persalinannya pun lancar. Dan meningkatkan dan mengembangkan program-program terkait promosi kesehatan Ibu dan Anak (KIA).
Pengembangan Media Pembelajaran Aplikasi Tentang Variasi Permainan Bulutangkis untuk Guru KKG PJOK SD Kelas IV
Authors: Huda Muhammad Rifqi Mafatikhul , Kurniawan Ari Wibowo
Published: October 2021

Abstract: Learning media is a means used to improve the learning process, the delivery of material content by educators to students by using assistive devices. The purpose of this research is to develop learning media for variations of badminton games for KKG PJOK elementary school teachers for grade IV which is packaged in an attractive way in the form of an articulate storyline application 3. The method used in this study uses the Lee and Owen research and development model, by following 5 procedures. stages. The results of data analysis showed that 91 percent of media experts, 75 percent of PJOK experts, 75 percent of learning experts, 95 percent of game experts, and 95 percent of badminton experts stated that the product was good. The results of the overall product trial involved 33 KKG teachers with 8 percentages of small group trials (81.3 percent) and 25 percentages of large group trials (82.1 percent). Based on these data, it can be concluded that this product is valid and suitable for use by PJOK teachers at SD Sananwetan District, Blitar City.

Abstrak: Media pembelajaran merupakan sarana yang digunakan untuk menyempurnakan proses pembelajaran, penyampaian isi materi oleh pendidik kepada peserta didik dengan menggunakan alat bantu. Tujuan dari penelitian ini adalah untuk mengembangkan media pembelajaran variasi permainan bulutangkis untuk guru KKG PJOK SD kelas IV yang dikemas secara menarik dalam bentuk aplikasi articulate storyline 3.  Metode yang digunakan dalam penelitian ini menggunakan model pengembangan research and development Lee and Owen, dengan mengikuti 5 prosedur tahapan. Diperoleh hasil analisis data yang menunjukkan 91 persen ahli media, 75 persen ahli PJOK, 75 persen ahli pembelajaran, 95 persen ahli permainan, 95 persen ahli bulutangkis menyatakan bahwa produk baik. Hasil uji coba keseluruhan produk melibatkan 33 guru KKG dengan pembagian uji coba kelompok kecil 8 persentase (81,3 persen) dan uji coba kelompok besar 25 persentase (82,1 persen).  Berdasarkan data tersebut dapat disimpulkan bahwa produk ini valid dan layak digunakan oleh guru PJOK SD Kecamatan Sananwetan Kota Blitar.
Hubungan Pendidikan dan Pengetahuan Ibu, Dukungan Keluarga, dan Faktor Budaya Terhadap Pemberian ASI Parsial
Authors: Ambarsari Sarastya , Yunus Moch. , Hapsari Anindya
Published: October 2021

Abstract: Partial breast milk is breast milk and other foods other than breast milk that are given when the baby is under six months old with continuous feeding or when the baby is born, such as formula milk, porridge, and other complementary foods (prelacteal food). The study aims to determine the connection between education and knowledge of mothers, family support, and culture on partial breastfeeding. This research utilize a cross sectional research methodology and was an analytic observational study. In January until February 2021, data was collected. The sample during this study was 43 respondents. Purposive sampling methodology for victimization sampling. During this study, questionnaire and interview were used as the instrument and the info analysis employed in this study was Spearman rho. The results demonstrated that, the education, family support, and cultural factor variables have no relationship with partial breastfeeding with a p-value of 0,134, 0,091, and 0,934. Meanwhile, the knowledge variable has a relationship with partial breastfeeding with a p-value of 0,033. The conclusion obtained is that there is no significant relationship between mother's education, family support, and culture on partial breastfeeding, but there is a significant relationship between the knowledge of partial breastfeeding.

Abstrak: Air susu ibu parsial adalah ASI dan makanan lain selain ASI yang diberikan pada saat bayi berusia dibawah enam bulan diberikan secara kontinyu atau saat bayi baru lahir seperti susu formula, bubur, serta makanan tambahan lainnya (makanan prelakteal). Ibu memberikan ASI parsial disebabkan oleh banyak faktor, yaitu pendidikan ibu, pengetahuan ibu, dukungan keluarga, serta faktor budaya. Penelitian bertujuan untuk mengetahui hubungan antara pendidikan dan pengetahuan ibu, dukungan keluarga, serta faktor budaya terhadap pemberian ASI parsial. Penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional. Pengumpulan data dijalankan pada bulan Januari-Februari 2021. Populasi penelitian ini adalah ibu yang memiliki bayi berusia 6-12 bulan dengan jumlah sampel sebanyak 43 responden. Pengumpulan sampel pada penelitian dengan metode purposive sampling. Instrumen dalam penelitian menggunakan kuesioner dan wawancara serta analisis data menggunakan Spearman rho. Hasil penelitian membuktikan bahwa, variabel pendidikan, dukungan keluarga, dan faktor budaya tidak terdapat hubungan signifikan terhadap pemberian ASI parsial dengan p-value yaitu 0,134, 0,091, dan 0,934. Sedangkan, variabel pengetahuan memiliki hubungan signifikan dengan pemberian ASI parsial dimana p-value adalah 0,033. Diperoleh kesimpulan yaitu tidak ada hubungan signifikan antara pendidikan ibu, dukungan keluarga, dan faktor budaya terhadap pemberian ASI parsial, namun terdapat hubungan signifikan antara pengetahuan ibu terhadap pemberian ASI parsial.
Retracted: Studi Literatur: Status Infeksi Tuberkulosis dan Progresi Penyakit HIV
Authors: Solekhah Umi , Gayatri Rara Warih , Tama Tika Dwi
Published: October 2021

This paper has been withdrawn at the request of the author and has been retracted.