bluuebunny/crossref_metadata_2025 huggingface dataset:
Caracterización bioinformática de mutaciones en las proteínas presenilina-1, presenilina-2 y proteína precursora de amiloide en relación con enfermedad de Alzheimer familiar
Authors: Soto-Ospina Alejandro , Cataño-Sanchez Elias , Bedoya-Berrío Gabriel de Jesús , Araque-Marín Pedronel , Villegas-Lanau Andrés
Published: January 2022

Introducción: La enfermedad de Alzheimer se manifiesta como la muerte neuronal debido al daño en el tejido nervioso y cuyo marcador neuropatológico, son los depósitos de proteína como placas amiloide y ovillos neurofibrilares. Objetivo: Relacionar la clínica reportada para la enfermedad de Alzheimer Familiar y los cambios de 10 mutaciones seleccionadas en las regiones susceptibles, para entender el efecto en la estructura proteica, a partir de la caracterización bioinformática. Metodología: Se recopila la información reportada de las bases de datos Alzforum, Pubmed, Uniprot y Embl, el análisis de susceptibilidad a la mutación se hace con el software SNAP2 de Rostlab y las modificaciones postraduccionales se hacen con la herramienta Swiss-ExPASY. Resultados: Se establece una tabla de frecuencias orientada a los casos clínicos asociados a las mutaciones missenses que producen enfermedad de Alzheimer y se encontró la frecuencia de cambios de aminoácido y se comparó con la composición de aminoácidos presentes para PS1, con un porcentaje de 12% para Leu, en PS2 con Leu en 12.9% y para el fragmento carboxi terminal de APP de 99 aminoácidos con un valor de 13.1% para Val. Discusión y conclusión: Los aminoacidos que producen el cambio a partir de sus características químicas, fueron más frecuentes los no polares y se estima que se da por la proporción tan alta de estructura proteica localizada en la membrana neuronal. Con el análisis de susceptibilidad se complementa el efecto del cambio para los 20 aminoacidos en la estructura de la proteína, orientada por los cambios de polaridad.
Proposal Penelitian Korelasi Penguasaan Kosakata Keterampilan Menulis Teks Berita Siswa SMA Negeri 2 Batang Anai
Authors: Maulana Rafi
Published: January 2022

Penelitian ini membahas Korelasi Penguasaan Kosakata dengan Keterampilan Menulis Teks Berita Siswa SMA Negeri 2 Batang Anai.
Proposal Refi Gustini Struktur, Diksi, dan Konjungsi Teks Prosedur Karya Siswa Kelas VII SMP Negeri 7 Sijunjung
Authors: Gustini Refi
Published: January 2022

Catatan terkait dengan proposal yang berjudul struktur,diksi, dan konjungsi teks prosedur karya siswa kelas VII untuk memenuhi tugas mata kuliah metodologi penelitian bahasa indonesia
International Capital Inflows and Poverty: Evidence from Developing Countries.
Authors: Le Thanh Tung
Published: January 2022

Poverty reduction is an important one of the long-term global goals. This paper analyses the impact of international capital inflows on poverty with a sample covering 26 developing countries in the Asia-Pacific region. A panel dataset is collected over the period of 1980-2015. The results conclude some new findings, which show international capital inflows have two kinds of effects on the poverty rate. The result shows that remittances and trade openness has positive effects on the poverty rate of the economies. On the other hand, external debt and official development assistance have negative effects on poverty in the region. Our findings lead to some valuable implications, in which, the policymakers need more careful when using the external debt as well as official development assistance to support economic growth because these tools can make the more serious on the poverty in countries. However, the policymakers can use the remittances as an important international capital to solve the lack of internal financial resource. Besides, the result points out that trade openness is a good tool for decreasing the poverty rate by trading with the outside.
Factors affecting consumers purchase decision: A case study in car market in Ho Chi Minh City
Authors: Le Thanh Tung
Published: January 2022

This paper aims to examine the factors affecting purchase decision cars of consumers to enable car manufacturers to find out the possible vulnerability between the expectations of customers and products on the market. The research uses a random survey with a group of 271 consumers in Ho Chi Minh City. Results of factor analysis and regression show that three factors including: safety features, reliability and resale value actually have positive impact on the purchasing decision automobiles consumer. On the practical significance, the study proposes some solutions to help manufacturers and distributors offering reasonable policies in order to improve sales, profits, expanding markets in Vietnam. Besides, the study also has some limitations, so the next study should be expanded and further research to be able to explain more of the factors affecting purchase decision cars of consumers.
Proposal Penelitian_Miftahul Ulfa_19016031
Authors: Ulfa Miftahul
Published: January 2022

Keterampilan menulis sangat berpengaruh bagi manusia disebabkan dengan adanya tulisan, seseorang bisa memperoleh suatu pengetahuan atau informasi. Tarigan (dalam Mustadi, 2014) mengungkapkan keterampilan yang dapat digunakan seseorang untuk berkomunikasi baik itu secara daring (tatap muka) ataupun luring (secara tidak langsung) disebut dengan menulis. Alwasilah (Hayatunisa, 2014) mengatakan bahwa menulis bukan hanya bagaimana orang menghasilkan beberapa kata, tetapi juga membutuhkan waktu yang panjang dan proses yang kompleks. Liang Gie (Prayuningtyas, 2017: 113) mengatakan rangkaian kegiatan yang dilakukan seseorang untuk mengungkapkan suatu gagasan kepada pembaca disebut kegiatan menulis. Pada zaman sekarang yaitu zaman yang canggih dan modern, keterampilan menulis tentu sangat dibutuhkan baik itu dunia pendidikan, dunia teknologi, kehidupan sosial, maupun kehidupan politik (Samini & Mamik, 2020). Dalam pembelajaran bahasa Indonesia, keterampilan menulis sudah diajarkan kepada siswa dari sekolah dasar (SD) sampai perguruan tinggi (Sarnan, 2018).
Sustainability accounting and reporting: an ablative reflexive thematic analysis of climate crisis, conservative or radical reform paradigms
Authors: Huston Simon
Published: January 2022

Every year the global financial system sends trillions of dollars to finance environmental destruction, but the climate crisis forces change. Notwithstanding vested interests and the unrecognised paradox of adopting environmental business strategies, the implementation of sustainability accounting and reporting (SAR) is imperative to catalyse economic transition away from fossil-fuel and plastic configurations to more sustainable ones. The research proceeded sequentially. First, it scanned the backdrop to the SAR problem and identified key associated institutions and a corpus of recent literature. An initial review to disentangle its conflicting threads generated three themes of ‘climate crisis’ and ‘conservative’ or more ‘radical’ SAR reform paradigms. Iteratively harnessing this thematic lens, the investigation re-examined the SAR literature corpus. It detected fragmented SAR responses to the climate crisis. Accordingly, the research reformulated its first theme to ‘dystopic climate crisis fragmentation’ but only refined the other two conservative or radical themes to take account of materiality and the split between Anglo-Saxon (IFRS, SSAB) or global and continental institutions (UN, EU, GRI). Conservatives defend incremental standard improvements but retain a single materiality investor-focus. Radicals seek to implement double materiality with a broader spectrum of stakeholders in mind. Both approaches have theoretical as well as pragmatic advantages and disadvantages, so the SAR contention rumbles on. Whilst the standard setting landscape is evolving, division, paradox and contention remain. Given vested interests in the destructive status quo, it would be naïve to expect a harmonious SAR Ithaca to emerge anytime soon. Yet the challenges impel urgent action.
Struktur dan Ciri Kebahasaan Teks Eksplanasi Siswa Kelas VIII SMP Negeri 13 Padang
Authors: Livenza Oryn
Published: January 2022

Menulis teks eksplanasi merupakan salah satu kompetensi dasar yang harus dicapai olehsiswa. Kegiatan ini menuntut siswa untuk lebih kreatif, inovatif, dan ekspresif dalammengungkapkan ide atau gagasan. Teks eksplanasi merupakan teks yang bertujuanmenjelaskan tahapan-tahapan atau proses terjadinya suatu peristiwa atau fenomena.Fenomena yang dijelaskan berupa fenomena alam, sosial, maupun budaya. Tujuanmenulis teks eksplanasi di sekolah agar siswa dapat memperkaya pengetahuan merekadengan cara menuliskan fakta mengenai fenomena-fenomena yang terjadi di lingkungansekitarnya.
Feby.19421057.Cloud Computing.4
Authors: Savinsaka Javandra
Published: January 2022

Tugas cloud computing
Wawasan Nusantara dalam Pertahanan dan Keamanan
Authors: Putri Vingki Maulana
Published: January 2022

Wawasan Nusantara merupakan hal yang penting bagi bangsa Indonesia. Wawasan ini menjadi acuan bagi setiap individu untuk membangun dan memelihara tuntutan Negara Kesatuan Republik Indonesia. Wawasan nusantara memuat pandangan atau visi dalam mewujudkan tujuan dan cita-cita bangsa Indonesia. Dan merupakan hal yang penting bagi bangsa Indonesia. Wawasan ini menjadi acuan bagi setiap individu untuk membangun dan memelihara tuntutan Negara Kesatuan Republik Indonesia. Makna wawasan nusantara adalah cara pandang bangsa Indonesia terhadap rakyat, bangsa, dan wilayah Negara Kesatuan Republik Indonesia (NKRI) yang meliputi darat, laut, dan udara di atasnya sebagai satu kesatuan politik, ekonomi, sosial, budaya, dan pertahanan keamanan. Upaya untuk menanamkan jiwa nasionalisme pada warga negara Indonesia adalah dengan menjadikan konsep wawasan Nusantara wajib diketahui dan diketahui oleh setiap warga negara Indonesia melalui pengenalan warga negara terhadap kondisi geografis dan demografis Indonesia. Dengan pengenalan ini, upaya penyadaran warga negara terhadap kondisi negara akan mengubah sikap warga negara untuk menjadi upaya sadar dalam mempertahankan wilayah kedaulatan negaranya, sehingga setiap generasi tidak akan rela NKRI jatuh dan dikuasai oleh negara tetangga kita.Kata kunci : Wawasan Nusantara, pertahanan dan keamanan, nasionalisme
AXIOLOGICAL ANALYSIS ON NETFLIX SERIES "SQUID GAME" AS AN EFFORT TO INCREASE AWARENESS OF SOCIAL ISSUES AMONG GENERATION Z
Authors: Mukarromah Bakdiyatul , 'Aisy Jihan Aqil Rihhadatul , Pandin Moses Glorino Rumambo
Published: January 2022

The internet is one of the impacts of new technology development, which can be used to find out the culture that exists in certain regional areas. The swift enlargement of information and communication technology has affected the public culture, both in the form of positive and negative impacts. Improvements and technological advances offered in this era make it easier for the community to access many things, one of which is entertainment media such as Netflix. Netflix's new series entitled “Squid Game” is being watched by millions of people around the world because of its unique storyline; it tells the story of a group of adults who are deeply in debt, who struggle to get a prize worth billions of Won (the official currency of South Korea) with their lives at stake. Unfortunately, the young generation nowadays is only a drama connoisseur who just follows trends, without exploring the messages and values contained in them. Therefore, the author analyzes the Netflix series "Squid Game" using an axiological approach as an effort to increase awareness of social issues among generation Z. This study uses a qualitative method with google form as an observation instrument and relevant literature sources. Academically, this research is hoped to contribute to science development which is related to the philosophy of science, and axiology in particular. Practically, it is hoped that it can be useful for readers, especially as a stimulant in the practice of axiological thinking in everyday life. This research shows that Generation Z at first was not aware of the social issues contained in the Squid Game. However, after getting a little stimulant, they can identify social issues that occur in the Squid Game, compare them with social issues in Indonesia, and consider Squid Game as a way to increase awareness of Generation Z on social issues.
Impact of Social Network Usage on Academic Performance of the Vietnamese Students
Authors: Le Thanh Tung
Published: January 2022

Social networks and communication on theInternet have an important role in people's daily lifeworldwide. This paper examines the impact of Socialnetwork usage on the Academic performance of students. The research data were collected from a stratified sampling survey including 576 Vietnamese undergraduate students. The research model has five independent variables (Perceived usefulness, Perceived ease of use, Social influences, Facilitating conditions, Community identity), one mediating variable (Social network usage), and onedependent variable (Academic performance). The studymethods include the Cronbach’s alpha test, the Exploratory factor analysis, the Confirmatory factor analysis, and the Structural equation modeling are employed toquantitatively analyze the relationship among variables.The result finds that there are positive and significantimpacts of Perceived usefulness, Perceived ease of use,Social influences, Community identity on Social networkusage. The impact of Facilitating conditions on Socialnetwork usage is positive, however, it is not significant.The result also concludes that there is a positive andsignificant impact of Social network usage on theAcademic performance of students. Besides, the empiricalstatistical data indicates that social networks are really apopular and familiar tool for helping students tocommunicate with each other in Vietnam. Finally, thestudy result suggests that educational managers may usesocial networks as an informal tool to enhance not only the academic performance of students but also othereducational activities in universities.
PERANAN PERANGKAT LUNAK KOMPUTER DALAM SISTEM INFORMASI MANAJEMEN
Authors: Hidayat Ahmad Fadhil
Published: January 2022

Pemrograman PC adalah salah satu perangkat yang diharapkan untuk menjalankan PC. Pemrograman adalah gadget yang tidak boleh terlihat dan dihubungi secara langsung, namun harus dimungkinkan oleh klien. PC (pemrograman) adalah bermacam-macam informasi elektronik yang dikumpulkan dan dipesan oleh PC, informasi elektronik yang disimpan oleh PC dapat terdiri dari proyek atau perintah yang akan menjalankan perintah. Pemrograman juga disebut sebagai penerjemah perintah yang dijalankan oleh klien PC untuk dikirim atau ditangani oleh peralatan. Melalui produk atau pemrograman ini, PC dapat menjalankan tuntutan. Sebagai aturan umum, atau pemrograman dapat dikelompokkan menjadi tiga bagian, untuk lebih spesifik, pemrograman kerangka kerja, pemrograman kerangka aplikasi dan dialek pemrograman.
Factors affecting on the Apartment purchase decision of officers in Small and Medium - sized enterprises in Ho Chi Minh City
Authors: Le Thanh Tung
Published: January 2022

In recent years, demand for housing has increased in Ho Chi Minh City (HCMC) despite of apartment market’s felling into the freeze. Besides, apartment`s price has continuously dropped, but the situation has not improved much. Do not the real estate companies really understand the need of buyers ? This paper researches factors affecting the decision to purchase apartment of officers in Small and Medium-sized enterprises (SMEs) in HCMC. We surveyed 321 buyers, using Cronbach`s Alpha Scale testing method, Exploratory Factor Analysis method and multivariate regression methodology. The results indicated that the decision to buy an apartment of officers was affected by three important factors which are habitat environment, characteristics and finance respectively. From the research results, this paper also proposes some solutions to bring the supply and the demand of apartment in HCMC closer together, thereby contributing to solve difficulties for market.
Insights from social sciences can help build an eco-surplus culture for conservation policymaking
Authors: Nguyen Minh-Hoang
Published: January 2022

In line with conservation social scientists, I contend that understanding how people adapt and change their attitudes and behaviors towards biodiversity concepts is crucial for tackling biodiversity loss through building an eco-surplus culture in urban areas. My argument can be defended by various studies that have confirmed the positive relationships between interactions with nature and attitudes towards biodiversity and the biophilia hypothesis.
Age Differences in the Social Associative Learning of Trust Information
Authors: Seaman Kendra Leigh , Christensen Alexander P. , Senn Katherine , Cooper Jessica , Cassidy Brittany Shane
Published: January 2022

Trust is a key component of social interaction. Older adults, however, often exhibit excessive trust relative to younger adults. One explanation is that older adults may learn to trust differently than younger adults. Here, we examine how younger (N=33) and older adults (N=30) learn to trust over time. Participants completed a classic iterative trust game with three partners. Younger and older adults shared similar amounts but differed in how they shared money. Compared to younger adults, older adults invested more with untrustworthy partners and less with trustworthy partners. As a group, older adults displayed less learning than younger adults. However, computational modeling suggests that this is not because older adults learn differently from positive and negative feedback than younger adults. Model-based fMRI analyses revealed several age-and learning-related differences in neural processing. Specifically, we found that older learners (N= 19), relative to older non-learners (N= 11), had greater reputation-related activity in mentalizing/memory areas while making their decisions. Collectively, these findings suggest that older adult learners use social cues differently from non-learners.
Educational interventions involving physical manipulatives for improving children’s learning and development: a scoping review
Authors: Byrne Elizabeth Mary , Ramchandani Paul G.
Published: January 2022

WHY DID WE DO THIS RESEARCH?Hands-on learning activities with physical objects – or physical manipulatives (PMs) – can be great at encouraging children’s active participation in learning. Cast your mind back to your own childhood: do you remember using items like counters, shapes, or fraction bars in school? If so, you were using PMs! We wanted to find out what kind of research has been done on educational programmes involving PMs.WHAT DID WE DO?We conducted a scoping review – a type of literature review used to identify and broadly describe a body of research according to certain inclusion criteria. We searched several academic databases for studies that have tested the effectiveness of PM interventions with primary-age children; 102 studies met our inclusion criteria and were synthesised in the review.WHAT DID WE FIND?Most studies involved children between 4-6 years in school settings. They spanned 26 different countries, but almost all took place in high- or middle-income contexts, typically the USA. The interventions involved different PMs and hands-on activities (e.g., block building, shape sorting, paper folding), and evidence relating their effectiveness was mixed. Whilst some studies reported benefits to children’s math, spatial, or literacy skills, others did not, and many were hindered by methodological shortcomings. This means we must be cautious when drawing conclusions about the overall effectiveness of PM interventions. Nevertheless, the findings illustrate the many ways hands-on experiences with PMs can facilitate children’s active engagement in learning. Going forward, higher quality research is needed, as well as more studies testing PM interventions in lower-income contexts.
Impact of Training & Development and Career Planning on Employee Involvement
Authors: Dr. Gopal Man Pradhan  , Dr. Prakash Shrestha
Published: January 2022

The purpose of this research is to investigate the impact of training and development as well as career planning in Nepalese service sector organizations. Data for this study were gathered from service organizations such as banks, insurance companies, telecommunications companies, hospitals, and colleges. In total, 502 questionnaires were distributed, and 82.97 percent of the copies that were filled out and returned were used in the study. Descriptive statistics, correlation, and multiple regression were used to analyze the data. Organizational training and development and career planning, according to the study's findings, have a significant impact on employee involvement in their jobs and performance. As a result, Nepalese service sector organizations must make provisions of the budget for additional employee training and development programs. Similarly, it is necessary to provide employees with career development opportunities so that they can stay with the company for an extended period.
Lipid Profile in Patients with Lichen Planus in a Tertiary Care Hospital: A Descriptive Cross-Sectional Study
Authors: Karki Sunita , Rai Anjan , Pradhan Manish
Published: January 2022

Background: Lichen planus is an immune mediated disease that affects the skin and the mucous membranes. Although the etiology and pathogenesis are not fully understood, it is believed that lichen planus represents a T-cell-mediated inflammatory disorder which produces disturbances of lipid metabolism.

Materials and Methods: Patients with the clinical diagnosis of lichen planus were included in the study after taking informed written consent. In total 40 patients were included in the study. Serum lipid profile was performed in the medical laboratory of Nobel Medical College Teaching Hospital.

 Results: Out of 40 patients, 13(32.5%) patients had dyslipidemia. Overall dyslipidemia was seen more in female patients (53.8%) than in male patients (46.2%). In our study, hypertrophic (32.5%) followed by eruptive (27%) and mucosal (25%) lichen planus were the most common variant.

Conclusion: This study demonstrated that about one-third of lichen planus patients showed deranged lipid levels in blood so for patients presenting with lichen planus physicians should consider screening them for dyslipidemia.
Predictors of Obesity among Type 2 Diabetes Mellitus Patients Attending a Tertiary Care Center of Province 1, Nepal
Authors: Roy Pratap Kumar , Baral Dharanidhar , Gautam Arjun , Subedi Sarita
Published: January 2022

Background: Obesity and Diabetes Mellitus type 2 have a known association. Yet, the socio-demographic predictors of obesity in special populations like ours (Asian) who have DM remain unclear. The purpose of this study was to determine the socio-demographic predictors of obesity among newly diagnosed Diabetes Mellitus in adults.

Materials and Methods: This was a descriptive cross-sectional study conducted in endocrine OPD of Nobel medical college. Total 124 subjects were enrolled who were newly diagnosed Diabetes Mellitus over a period of 1 year. Detailed history was taken for demographic and clinical variables. Height, weight, waist circumference and blood pressure were measured. Besides, Body Mass Index, the dependent variable, was calculated. Subjects were considered to have diabetes based on their fasting and postprandial blood sugar level for the first time.

Results: The prevalence of obesity among the study population was 39.5%, overweight was 45.2%. Predictors for this study for obesity were found as abnormal blood pressure and hospital visit after symptoms development.

Conclusion: Obesity is a important risk factor for Diabetes Mellitus and higher prevalence of obesity among type 2 diabetes was observed. Predictors for this study for obesity were found as abnormal blood pressure and hospital visit after symptoms development
Short Term Clinical Outcome of Micro Lumbar Discectomy in Tertiary Care Center
Authors: Chaudhary Pramod , Kafle Prakash , Joshi Narendera , Gautam Ujwal
Published: January 2022

Background: Minimal invasive open lumbar microdiscectomy has been associated with good success rate and low morbidity. The present study is aimed to evaluate the clinical outcome of patients who underwent open minimal invasive open lumbar microdiscectomy for herniated intervertebral disc.

Materials and Methods: This is a prospective observational hospital based study of prolapsed lumbar intervertebral disc operated in the department of neurosurgery at Nobel Medical College Teaching Hospital, Biratnagar, Nepal from January 2018 to June 2021. All patients of lumbar herniated intervertebral disc subjected for surgery were included. Recurrent prolapsed intervertebral disc, Disc surgery requiring stabilization was excluded from the study. During surgery types of prolapsed intervertebral disc, level and operative time were noted. In the post-operative period Visual Analogue Scale was used to assess the change in severity of pain. Duration of hospital stay and the complications occurred were also noted.

Results: The mean age of the study population was was 41.50 (±14.56) years ranging from 20 years to 79 years. The commonest lumbar prolapsed intervertebral disc was at L4-L5 level. The mean operative time was 42 minutes excluding the time for anaesthesia preparation. There was statistically significant difference (p<0.001) in pre-operative and post-operative Visual Analogue Scale. Mean duration of hospital stay was 5.58 (1.87) days.

Conclusion: A through workup and surgical planning is associated with better outcome avoiding complications in minimal invasive open micro lumbar discectomy.
Thyroid Dysfunction and its Effect on Red Blood Cell Parameters
Authors: Singh Samir
Published: January 2022

Background: Thyroid hormones are necessary for the growth and development, cellular differentiation, physiological function and metabolic regulation of almost all tissues in our body. Thyroid disorders are accompanied by alteration in hematological profile. This study aims to evaluate the effect of thyroid dysfunction on red blood cell parameters.

Materials and Methods: This case-control observational study was conducted in the Department of Clinical Biochemistry, KIST Medical College and Teaching Hospital (KISTMCTH), Lalitpur, Nepal from January 2021 to June 2021.Total number of recruited subjects was 248, out of which 67 were labeled as hypothyroid, 7 were hyperthyroid and 174 were euthyroid as control. Subjects for all three groups were between 16-93 years old. Thyroid hormone profile of patients was determined by Siemens ADVIA Centaur CP immunoassay analyzer and hematological parameters by automated hematology analyzer Sysmex XN-550. Results were analyzed by SPSS 21 software and a chi-square test was applied to see significant differences among the groups.

Results: The mean age of all study participants was 42.08±17.27 years and female constituted 74.6% of total subjects. Analysis of the data obtained a statistically significant difference in the mean hemoglobin (p<0.001) between hypothyroid and euthyroid groups. The difference was not significant for hemoglobin (p=0.252) among hyperthyroid and euthyroid groups. There was no statistical significant difference between thyroid cases and control for MCV, MCH and MCHC.

Conclusion: The current study concluded that thyroid dysfunction have a significant effect on red blood cell parameters. Hematological parameters should be evaluated in patient with thyroid dysfunction.
Relationship Between Functional Activity And Nutritional Status, Manual Ability And Intelligence In Children With Cerebral Palsy
Authors: Rosdiana Ika , Daniswari Verina Gian , Sura Getri , Ariestiani -
Published: January 2022

International Journal of Human and Health Sciences Vol. 06 No. 01 January’22 Page: 30-35
Manifestations of Polycystic Ovary Syndrome are Similar Regardless of the Degree of Menstrual Cycle Variation
Authors: Zamila Begum Moriom , Banu Hurjahan , Morshed Md Shahed , Shah Sukanti , Begum Afroza , Sultana Tania , Akhtar Nazma , Fariduddin Md , Saleh Ahmed Abu , Hasanat MA
Published: January 2022

Background: Menstrual irregularities may predict over adverse consequences in polycystic ovary syndrome (PCOS).Objective: To observe the relation of variants of menstrual cycles with clinical and biochemical features of PCOS.Methods: This cross-sectional study encompassed 200 PCOS women diagnosed by Rotterdam criteria and 120 age-matched healthy controls. Subgroups were classified according to menstrual cycle length as: polymenorrheic (<21 days), eumenorrheic (21-35 days), oligomenorrheic (36 days-3 months) and amenorrheic (>3 months). Glucose was measured by glucose oxidase, lipid by glycerol phosphate dehydrogenenase-peroxidase and all hormones by chemiluminescent immuno-assay method.Results: Around 86% of PCOS patients had menstrual irregularity, among which 75% had oligomenorrhea followed by amenorrhea (9%) and polymenorrhea (2%). All the subgroups of PCOS patients (polymenorrhea excluded from further analyses) had significantly poor metabolic manifestations than the control namely insulin resistance (IR), impaired glycaemic status, general and central obesity, metabolic syndrome and dyslipidaemia. Acanthosis nigricans (AN), hyperandrogenemia (HA) and IR had significant predictive association with PCOS patients with both irregular [OR (95% CI)- AN: 21.994 (6.427, 75.267), p<0.001; HA: 27.735 (8.672, 88.704), p<0.001; IR: 7.268 (2.647, 19.954), p<0.001] and regular cycle [AN: 16.449 (3.830, 70.643), p<0.001; HA: 24.635 (6.349, 95.590), p<0.001; IR: 6.071 (1.658, 22.234), p=0.006] in reference to control group. None of the variables had significant predictive associations with irregular cycle in reference to regular cycle in patients with PCOS.Conclusion: Oligomenorrhea was the most common variant of menstrual irregularity in PCOS patients. All menstrual variants including eumenorrhea had similar manifestations in PCOS women, but poorer than controls.International Journal of Human and Health Sciences Vol. 06 No. 01 January’22 Page: 96-103
The misconception in graphene’s dispersion energy simulations
Authors: Syella Ayunisa Rani  , Heru Kuswanto  , Himawan Putranta  , Aditya Yoga Purnama  , Wipsar Sunu Brams Dwandaru
Published: January 2022

This study aims to find equations and simulations that satisfy the characteristics of graphene’s energy dispersion and identify misconceptions that may occur. Here we give students nine articles about graphene’s dispersion energy. They were asked to identify the equations, parameters, and software used in each of the articles. The assignment was then to make the distribution of the data in a spreadsheet. The parameters used were the lattice constant of 2.46 Å, the range of the k wave function for the x and y axes of -2πa to 2πa, and the interval for each range of 0.1. Each equation is divided into two parts, E(+) and E(-). The analysis was carried out by making a slice in the middle of the x and y axes, as well as the main and off-diagonals. Graphene has Dirac points where the band gap is zero. This means that there is no distance or very small distance between the valence and conduction bands. From this activity, it can be concluded that Rozhkov (2016) has the equations and simulations that best satisfy graphene’s dispersion energy. Misconceptions occur in almost all existing equations and simulations.
The quantum beam splitter revisited without a vacuum state
Authors: Nahmad Alexander , San-Roman-Alerigi Damian P , Hernández González Edna Magdalena , Barrios Erick , Armendariz Peña Gustavo , Velazquez Aguilar Víctor Manuel
Published: January 2022

In this article we explain in a new light two fundamental concepts ofquantum optics, the quantum beam splitter and the quantum interferometer, in termsof two state quantum wave functions. This method is consistent with the concept ofentanglement, and hence the algebra needed to describe them is reduced to additionsand products of the components of the quantum states. Furthermore, under thepremises of this method it is possible to study quantum states of greater complexity,like those arising from the addition and products of single photon states.
Technical Framework of Qatar’s Foreign Aid Policy: Guiding Documents and Operative Institutions (Rangka Kerja Teknikal Dasar Bantuan Asing Qatar: Dokumen Panduan dan Institusi Pelaksana)
Authors: Bashir Fadhl A. , Abdullahi Abdelsalam El Fatih
Published: January 2022

This paper presents essential aspects of the State of Qatar foreign aid policy (QFAP), which is closely tied to the wider country’s foreign policy. The study traces and explains vital foundations of the country’s foreign aid policy framework and its decision-making process, mainly the guiding documents and operative institutions. Evidently, the content and structure of these two technical elements reflect the political and socio-cultural background as well as the regional and global surrounding of the state of Qatar. Although it is an emerging donor, Qatar’s aid documents and institutions are showing radical development and prestigious institutionalizing. The technical guidance and the inclusiveness of QFAP documents and widespread operations of its institutions show that Qatar has further benefited from its partnerships and global engagements to advance its aid policy making. This research used face-to-face interviews with key Qatari officials and scrutinized the state official documents and quoted speeches and statements, in addition to other relevant academic materials.
Keywords: Foreign Aid Policy, Qatar, Documents, Institutions, Policy-Making.            
Abstrak
Artikel ini membentangkan aspek dasar bantuan luar negeri Qatar (QFAP), yang berkait rapat dengan rangka kerja umum dasar luar negeri yang lebih luas. Kajian ini mengesan dan menerangkan 2 asas penting rangka kerja dasar bantuan asing negara dan proses membuat keputusannya; iaitu dokumen panduan dan institusi pelaksana. Melalui kajian ini, jelas menunjukkan bahawa kandungan dan struktur kedua-dua elemen teknikal ini mencerminkan latar belakang politik dan sosio-budaya serta persekitaran serantau dan global negara Qatar. Walaupun Qatar merupakan penderma yang baru menonjolkan diri dalam landskap bantuan global, namun dokumen dan institusi bantuan Qatar menunjukkan ia sebagai perkembangan positif dan institusi yang berprestij. Panduan teknikal dan keterangkuman dokumen QFAP dan operasi meluas institusinya menunjukkan bahawa Qatar telah terus mendapat manfaat daripada perkongsian dan penglibatan globalnya untuk memajukan pembentukan dasar bantuannya. Kajian ini dijalankan berdasarkan temu bual langsung dengan para pegawai Qatar dan pakar yang berkaitan, di samping menganalisis dokumen dan laporan rasmi negara, memetik ucapan dan kenyataan rasmi, serta mengambil kira sumber akademik dan saintifik lain yang berkaitan.
Kata Kunci:  Dasar Bantuan Asing, Qatar, Dokumen, Institusi, Proses Pembentukan Dasar.
Pelaksanaan Konseling Awal pada Konselor Sekolah Menengah Pertama
Authors: Yuline Yuline
Published: January 2022

Abstrak

Penelitian bertujuan mendeskripsikan pelaksanaan konseling awal pada konselor dalam melaksanakan konseling individual. Metode penelitian yang digunakan adalah deskriptif dengan bentuk penelitian survei. Alat pengumpul data menggunakan angket dan wawancara. Analisis data menggunakan rumus persentase dan analisis rasional. Populasi penelitian sebanyak 35 konselor dari 23 SMP negeri dan 2 SMP swasta di Kabupaten Kubu Raya. Sampel penelitian menggunakan teknik sampling total sehingga yang menjadi sampel penelitian adalah seluruh populasi. Berdasarkan hasil penelitian, disimpulkan bahwa secara umum konselor dalam melaksanakan konseling awal berada pada kategori sedang dengan rincian: indikator menyiapkan diri konselor, mengobservasi, dan mendengarkan berada pada kategori baik; indikator menyiapkan diri konseli dan melayani secara pribadi berada pada kategori sedang; dan indikator menyiapkan konteks berada pada kategori rendah. Hasil penelitian juga menunjukkan bahwa konselor kurang memahami keterampilan konseling, keterbatasan ruang konseling, pengembangan diri konselor, dan keterbatasan literatur.

 

Abstract

The research aimed to describe the implementation of initial counseling to counselors in carrying out individual counseling. The research method used descriptive in the form of survey research. Data collection tools used questionnaires and interviews. Data analysis used the percentage formula and rational analysis. The research population was 35 counselors from 23 public junior high schools and 2 private junior high schools in Kubu Raya Regency. The research sample used a total sampling technique so that the research sample was the entire population. Based on the results of the research, it was concluded that in general the counselors in carrying out initial counseling were in the moderate category with details: indicators of preparing the counselor, observing, and listening were in the good category; indicators of preparing the counselee and serving personally are in the medium category; and indicators of setting up context are in the low category. The results also showed that counselors do not understand counseling skills, limited counseling space, counselor self-development, and limited literature.
Kelayakan Media Video Pembelajaran pada Submateri Sistem Endokrin
Authors: Astuti Agus , Panjaitan Ruqiah Ganda Putri , Titin Titin
Published: January 2022

Abstrak

Penelitian bertujuan mengetahui kelayakan video sebagai media pembelajaran pada submateri Sistem Endokrin kelas XI SMA. Penelitian menggunakan metode penelitian deskriptif. Tahapan penelitian meliputi tahap penyusunan materi isi media video dan validasi media video. Validasi dilakukan oleh lima validator. Instrumen penelitian menggunakan lembar validasi. Penilaian lembar validasi menggunakan skala Likert. Aspek yang dinilai yaitu aspek format, isi, dan bahasa. Data dianalisis menggunakan formula Lawshe. Hasil validasi menunjukkan rata-rata CVR pada aspek penilaian format, isi, dan bahasa lebih besar dari batas minimum Lawshe. Berdasarkan hasil penelitian, maka disimpulkan bahwa media video dapat digunakan sebagai media pembelajaran pada submateri Sistem Endokrin pada kelas XI SMA.

 

Abstract

The research aimed to determine the feasibility of video as a learning medium in the Endocrine System submaterial in class XI senior high school. The research used descriptive method. The research stages include the stage of compiling the video media content material and the video media validation stage. Validation was carried out by five validators. The research instrument used a validation sheet. The validation sheet assessment used a Likert scale. The aspects that assessed were format, content, and language. Data were analyzed using Lawshe's formula. The validation results showed that the average CVR in the aspect of format, content, and language assessment was greater than the Lawshe minimum limit. Based on the results of the study, it can be concluded that video media can be used as a learning medium in the Endocrine System submaterial in class XI senior high school.
Efektivitas LKPD Berbasis Blended Learning Berbantuan Multimedia Interaktif untuk Melatih Visual Spasial Peserta Didik
Authors: Hulu Gaferianto , Dwiningsih Kusumawati
Published: January 2022

Abstrak

Penelitian bertujuan untuk mengetahui keefektifan Lembar Kerja Peserta Didik (LKPD) berbasis blended learning berbantuan multimedia interaktif dalam melatih kemampuan visual spasial peserta didik pada materi Ikatan Kovalen.  Metode penelitian menggunakan one group pretest-posttest design dengan melakukan uji coba terbatas pada peserta didik Jurusan Kimia Analisis SMK Negeri 1 Cerme Gresik yang dipilih berdasarkan kemampuan peserta didik dari kemampuan rendah, sedang, dan tinggi sebanyak 15 orang.  Pretest dan posttest digunakan sebagai instrumen untuk mengetahui kemampuan visual spasial peserta didik. Data dianalisis secara deskriptif kuantitatif. Hasil penelitian menunjukkan bahwa data pretest dan posttest berdistribusi normal dan hasil rata-rata N-Gain pada kategori tinggi sehingga disimpulkan bahwa LKPD berbasis blended learning berbantuan multimedia interaktif dalam melatih kemampuan visual spasial peserta didik pada materi Ikatan Kovalen efektif sebagai bahan ajar.

 

Abstract

The research aimed to determine the effectiveness of the Student Worksheet (LKPD) based on blended learning assisted by interactive multimedia in training students' visual-spatial skills in the Covalent Bond material. The research method used a one group pretest-posttest design by conducting a limited trial on students of the Analytical Chemistry Department at SMK Negeri 1 Cerme Gresik who were selected based on the ability of students from low, medium, and high abilities as many as 15 people. Pretest and posttest are used as instruments to determine the visual-spatial ability of students. Data were analyzed descriptively quantitatively. The results showed that the pretest and posttest data were normally distributed with the average N-Gain in the high category, so it can be concluded that the LKPD based on blended learning assisted by interactive multimedia in training students' visual-spatial abilities on the Covalent Bond material is effective as teaching material.
Efektivitas Pembelajaran Daring bagi Guru Madrasah Ibtidaiyah di Masa Pandemi COVID-19
Authors: Aufa Minzani , Sari Kanthi Pamungkas
Published: January 2022

Abstrak

Tujuan penelitian adalah untuk menganalisis efektivitas pembelajaran daring bagi guru madrasah ibtidaiyah (MI) se-Kota Magelang. Metode penelitian yang digunakan adalah deskriptif kualitatif. Sumber data dan informasi utama diperoleh dari subjek penelitian dengan populasi sebanyak 31 orang yang terdiri dari 29 guru dan 2 kepala madrasah. Teknik pengumpulan data menggunakan observasi, dokumentasi, wawancara, dan angket. Teknik analisis data menggunakan analisis deskriptif. Berdasarkan hasil penelitian disimpulkan bahwa: pembelajaran daring di MI se-Kota Magelang selama masa pandemi COVID-19 berjalan secara “efektif”; guru telah menjalankan pembelajaran daring saat pandemi COVID-19; guru dapat menguasai “smartphone” dan “laptop” sebagai tool dalam pembelajaran daring; “WhatsApp” merupakan pilihan utama sebagai media dalam melaksanakan pembelajaran daring; dan guru “setuju” jika pembelajaran daring dilanjutkan dengan memperhatikan rencana pelaksanaan pembelajaran daring (RPPD) yang telah dibuat sesuai dengan indikator yang telah terukur sesuai dengan capaian pembelajaran.

 

Abstract

The research aimed to analyze the effectiveness of online learning for madrasah ibtidaiyah (MI) teachers throughout Magelang City. The research method used descriptive qualitative. The main sources of data and information were obtained from research subjects with a population of 31 people consisting of 29 teachers and 2 madrasah principals. Data collection techniques used observation, documentation, interviews, and questionnaires. The data analysis technique used descriptive analysis. Based on the results of the research, it was concluded that: online learning at MI in Magelang City during the COVID-19 pandemic was running "effectively"; teachers have been running online learning during the COVID-19 pandemic; teachers can master “smartphones” and “laptops” as tools in online learning; "WhatsApp" is the main choice as a medium in carrying out online learning; the teacher "agrees" if online learning is continued by paying attention to the online learning implementation plan (RPPD) that has been made in accordance with indicators that have been measured in accordance with learning outcomes.
Modern Approach towards Clinical Evaluation and Treatment of Alcohol Psychoses
Authors: Aliyev N.A. , Aliyev Z.N.
Published: January 2022

Based on the literature and our own data in article outlines current clinical picture of alcoholic psychosis (delirium tremens, hallusinosis, alcohol delusion psychoses, jealousy), and theirs modem treatment methods. To give separate recommendation on the therapy of the delirium tremens, hallusinosis, alcohol delusion psychoses, jealousy etc. These data are of great practical and theoretical significance.
The Effectiveness of Cultural Deep Breathing against Blood Pressure Reduction
Authors: Agussalim Agussalim , Asikin Muhammad , Podding Takko , Nasir M. , Abidin Abidin , Hasan Edi , Rahman Abd.
Published: January 2022

Elderly is a process of disappearing in the ability of tissues to repair themselves or replace themselves and maintain their normal structure and function. This study aims to find out the effectiveness of deep breathing against decreased blood pressure in the elderly who have hypertension. The study used the one group pre-post test. The sample used as many as 13 participants. The study used Purposive Sampling techniques and the tool used to obtain the data. The study used a paired sample t-test with a significance value of α=0.05. The results of this study showed that there was an effect of deep breathing on the decrease in blood pressure in the elderly who had hypertension on the first day and the third day with a value of p= 0.000<α = 0.05. There is an effect of giving deep breathing to decrease blood pressure in elderly people who have hypertension on the 4th day and the sixth day with a value of p= 0.000<α = 0.05. There is an effect of giving deep breathing to the decrease in blood pressure in the elderly who have hypertension.
The Effect of COVID on Child Maltreatment: A Review
Authors: Rokach Ami , Chan Sybil
Published: January 2022

This article addresses child maltreatment during the period where COVID-19 entered our lives in 2020. Repeated lockdowns kept children at home, away from school, from their support systems, and from their routine. Economic difficulties and having to look after the children who were at home were quite onerous on parents. The article explores the reasons that ACE increased during that time, and highlights what can parents, teachers, and the educational system do about it.
Esquirol-Séguin-Down Syndrome Associated with Atrial Septal Defect plus Tricuspid Regurgitation
Authors: Al-Mosawi Aamir Jalal
Published: January 2022

Background: Esquirol-Séguin-Down syndrome (Trisomy 21) was first described by Jean-Etienne Dominique Esquirol in 1838 and later by Edouard Séguin in 1846. Thereafter, in 1862, John Langdon Down, a British physician emphasized that the syndrome is a distinct form of mental retardation. Congenital cardiac defects are observed in more than one third of the patients with Esquirol-Séguin-Down syndrome, and in approximately 80% these cardiac defects are atrioventricular septal defect or ventricular septal defect with the former being more common. The association of Esquirol-Séguin-Down syndrome with atrial septal defect plus tricuspid regurgitation has been rarely reported. The aim of this paper is to report the rare association of Esquirol-Séguin-Down syndrome with atrial septal defect plus tricuspid regurgitation. Patients and methods: Two and half years old boy with Esquirol-Séguin-Down syndrome, developmental delay and abnormal echocardiography was studied, and the recent relevant literatures were reviewed. Results: Dysmorphic facial features included hypertelorism, oblique palpebral fissures, epicanthic folds, depressed nasal bridge and low set ears. Echocardiography showed atrial septal defect with tricuspid regurgitation. Conclusion: This paper reports the first case of Esquirol-Séguin-Down syndrome in Iraq associated with atrial septal defect plus tricuspid regurgitation.