bluuebunny/crossref_metadata_2025 huggingface dataset:
Ameliorative effect of polydatin on hyperglycemia and renal injury in streptozotocin-induced diabetic rats
Authors: Wang Lijuan , Huang Liji , Li Nan , Miao Junjun , Liu Wei , Yu Jiangyi
Published: October 2019

To investigate the effect of polydatin on glucose transporter, blood glucose homeostasis and renal injury in streptozotocin (STZ)-induced diabetic rats. The in vitro inhibitory effect of polydatin on sodium-glucose cotransporter-1 (SGLT1) and 2 (SGLT2) was determined using HEK293 cells. The inhibitory effect of polydatin on GLUT1 and GLUT4 was evaluated using 3T3-L1 adipocytes. Streptozotocin-induced diabetic rats were used for this study. Fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), urea nitrogen, serum creatinine and urinary protein were determined using biochemical analyzer. Histopathological examination was performed on renal tissue. Serum levels of interleukin 1Î² (IL-1Î²), tumor necrosis factor Î± (TNF-Î±), monocyte chemoattractant protein 1 (MCP-1) and C-reactive protein (CRP) were also determined. Polydatin significantly inhibited SGLT1/2 and exhibited high selectivity for both GLUT1 and GLUT4. It significantly and dose-dependently decreased hyperglycemia, enhanced urine glucose excretion in the diabetic rats. The polydatin treatment significantly ameliorated symptoms of DN such as polyuria, polydipsia and hyperphagia. The hypoglycemic effect of polydatin was maintained throughout the treatment period. In addition,the levels of IL-1Î², TNF-Î±, MCP-1 and CRP were significantly reduced in treated group. Treatment with polydatin significantly ameliorated most of the structural and morphological changes induced by STZ. Moreover, the levels of urinary protein, serum creatinine and urea nitrogen were significantly reduced after treatment with polydatin.  As a potential dual inhibitor of SGLT1/2, polydatin has high selectivity for GLUT1 and GLUT4. Its long-term administration delays the development of DN, protects renal function and ameliorates renal tissue injury.
Î²-Arrestin2 regulates the rapid component of delayed rectifier K+ currents and cardiac action potential of guinea pig cardiomyocytes after adrenergic stimulation
Authors: Shi Erdan , Zhou Xiaozhu , Li Dongcheng , Zhang Yuzhen , Yuan Jiamin , Zou Jiangang
Published: October 2019

A decrease in the rapid component of delayed rectifier potassium current (IKr) during chronic heart failure (CHF) prolongs action potential (AP), and plays a key role in the pathogenesis of ventricular arrhythmias. Î²-Arrestin2 has been shown to restore the inotropic reserve of Î²-adrenergic regulation, but little or nothing is known about its effect on intrinsic channel. This study investigated the role of Î²-arrestin2 in the regulation of cardiac hERG/IKr potassium channel and AP during chronic adrenergic stimulation. Single left ventricular myocytes were isolated from guinea pig heart, and were transfected with adenovirus encoding Î²-arrestin2, or Î²-arrestin2 siRNA or an empty adenovirus. Cell cultures containing 10 nM isoproterenol, 1 nM phenylephrine or vehicle alone (control medium) were electro-physiologically examined after 48 h of incubation. Action potential duration at 50 and 90 % of repolarization (APD50 and APD90) were measured using whole-cell patch-clamp recording. Sustained adrenergic stimulation significantly reduced the density of the IKr current (p < 0.001). Î²-Arrestin2 expression in cell cultures treated with isoproterenol or phenylephrine was significantly downregulated after adrenergic stimulation (p < 0.001). Overexpression of Î²-arrestin2 significantly attenuated isoproterenol or phenylephrine-induced reduction in IKr current. It also prevented the phenylephrine-induced prolongation of AP (p < 0.05 for APD50 and p < 0.001 for APD90), but did not significantly affect AP profile after exposure of the cardiomyocytes to isoproterenol (p > 0.05). Therefore, Increased levels of Î²-Arrestin2 weaken dysregulation of IKr current and prevent excessive AP prolongation, making it an effective anti-arrhythmic strategy.
WT1 influences apoptosis and proliferation of immature mice granular cells through regulation of the wnt/Î²-catenin signal pathway
Authors: Wang Juan , Qiu Jianping , Bo Le , Wu Zhinan , Zhou Anwen , Xu Wendan , Mao Caiping
Published: October 2019

It was to study the influence of Wilms tumor suppressor gene (WT1) on ovarian granular cells (GCs) in mice, and the molecular mechanism involved. LV-WT1 short hairpin ribonucleic acid (shRNA) vector was used to downregulate WT1 expression in granular cells (GCs). The effects of WTI on proliferation and apoptosis of GCs were investigated. Western blot and qRT-PCR were used to assay the mRNA and protein expressions of Bax/bcl-2 in GCs transfected with LV-WT1-RNAi. The expression levels of SUZ12, Wnt5a, Wnt11, Wnt4, Wnt3a, Wnt2 mRNA in GCs were also determined. LV-WT1-RNAi significantly reduced WT1 expression, increased apoptosis and inhibited proliferation of GCs. The inhibition of WT1 had no significant effect on the expression of bcl-2 in GCs. The expressions of Wnt2, Wnt4 and Wnt5a were augmented in WT1-knockdown GCs, relative to non-transfected cells. WT1 activation is necessary for maintaining early survival of GCs in follicles via activation of the Wnt/Î²-catenin signal pathway.
Sharp Caffarelli–Kohn–Nirenberg-Type Inequalities on Carnot Groups
Authors: Flynn Joshua
Published: October 2019

The main purpose of this paper is to establish several general Caffarelli–Kohn–Nirenberg (CKN) inequalities on Carnot groups G (also known as stratified groups). These CKN inequalities are sharp for certain parameter values. In case G is an Iwasawa group, it is shown here that the

L
2

{L^{2}}

-CKN inequalities are sharp for all parameter values except one exceptional case. To show this, generalized Kelvin transforms

K
σ

{K_{\sigma}}

are introduced and shown to be isometries for certain weighted Sobolev spaces. An interesting transformation formula for the sub-Laplacian with respect to

K
σ

{K_{\sigma}}

is also derived. Lastly, these techniques are shown to be valid for establishing CKN-type inequalities with monomial and horizontal norm weights.
Identities related to generalized derivations in prime ∗-rings
Authors: Boua Abdelkarim , Ashraf Mohammed
Published: October 2019

Let

ℛ

{\mathcal{R}}

be a prime ring with center

Z
⁢

(
ℛ
)

{Z(\mathcal{R})}

and

*

{*}

an involution of

ℛ

{\mathcal{R}}

.
Suppose that

ℛ

{\mathcal{R}}

admits generalized derivations F, G and H associated with a nonzero derivation f, g and h of

ℛ

{\mathcal{R}}

, respectively.
In the present paper, we investigate the commutativity of a prime ring

ℛ

{\mathcal{R}}

satisfying any of the following identities:
(i)

[

F
⁢

(
x
)

,

F
⁢

(

x
*

)

]

=
0

[F(x),F(x^{*})]=\nobreak 0

,
(ii)

[

F
⁢

(
x
)

,

F
⁢

(

x
*

)

]

=

±

[
x
,

x
*

]

[F(x),F(x^{*})]=\pm[x,x^{*}]

,
(iii)

F
⁢

(
x
)

∘
F

⁢

(

x
*

)

=
0

F(x)\circ\nobreak F(x^{*})=0

,
(iv)

F
⁢

(
x
)

∘
F

⁢

(

x
*

)

=

±

(

x
∘

x
*

)

F(x)\circ\nobreak F(x^{*})=\pm(x\circ\nobreak x^{*})

,
(v)

[

F
⁢

(
x
)

,

x
*

]

±

[
x
,

G
⁢

(

x
*

)

]

=
0

[F(x),x^{*}]\pm[x,G(x^{*})]=0

,
(vi)

F
⁢

(

x
⁢

x
*

)

∈

Z
⁢

(
ℛ
)

F(xx^{*})\in Z(\mathcal{R})

,
(vii)

F
⁢

(
x
)

⁢
G
⁢

(

x
*

)

±

H
⁢

(
x
)

⁢

x
*

∈

Z
⁢

(
ℛ
)

F(x)G(x^{*})\pm H(x)x^{*}\in Z(\mathcal{R})

,
(viii)

F
⁢

(

[
x
,

x
*

]

)

±

[
x
,

x
*

]

∈

Z
⁢

(
ℛ
)

F([x,x^{*}])\pm[x,x^{*}]\in Z(\mathcal{R})

,
(ix)

F
⁢

(

x
∘

x
*

)

±

x
∘

x
*

∈

Z
⁢

(
ℛ
)

F(x\circ\nobreak x^{*})\pm x\circ x^{*}\in Z(\mathcal{R})

,
(x)

[

F
⁢

(
x
)

,

x
*

]

±

[
x
,

G
⁢

(

x
*

)

]

∈

Z
⁢

(
ℛ
)

[F(x),x^{*}]\pm[x,G(x^{*})]\in Z(\mathcal{R})

,
(xi)

F
⁢

(
x
)

∘

x
*

±

x
∘
G

⁢

(

x
*

)

∈

Z
⁢

(
ℛ
)

F(x)\circ\nobreak x^{*}\pm x\circ\nobreak G(x^{*})\in Z(\mathcal{R})

for all

x
∈
ℛ

{x\in\mathcal{R}}

.
Finally, the restrictions imposed on the hypotheses have been justified by an example.
A study of differential prime rings with involution
Authors: Oukhtite Lahcen , Ait Zemzami Omar
Published: October 2019

The main goal of the present paper is to study some results concerning generalized derivations of prime rings with involution. Moreover, we provide examples to show that the assumed restriction cannot be relaxed.
Local affine selections of convex set-valued functions
Authors: Wąsowicz Szymon
Published: October 2019

It is well known that not every convex set-valued function admits an affine selection. One could ask whether there exists at least one local affine selection. The answer is positive in the finite-dimensional case. The main part of the note comprises two examples of the non-existence of local affine selections of convex set-valued functions defined on certain infinite-dimensional Banach spaces.
Revealing the mysteries of the Chora of Metaponto
Authors: Zuchtriegel Gabriel
Published: October 2019

The series of volumes edited by Joseph Carter on the rural landscape around the Greek colony of Metapontum in southern Italy represent a slow but steady revolution in the field of Classical studies. This latest addition to the series presents the results of excavations at the rural site of Pantanello, near modern Metaponto, first launched by the Institute of Classical Archaeology of the University of Austin in 1974. At that time, Classical archaeologists concentrated almost entirely on urban contexts, especially temples and public buildings. Rural sites were of interest only if they featured in the literary sources. To initiate fieldwork at an anonymous rural location such as Pantanello, where only some roof tiles and stone blocks were visible, was therefore a courageous undertaking for a young scholar such as Joe Carter at that time. That fieldwork, however, has proved to be seminal, not only because of the broad range of data that have been brought to light by Carter and his international team, but also because of the meticulous publication of the results in a series of high-quality volumes that have set a new benchmark. The volume under review, The Greek sanctuary at Pantanello, comprises three sub-volumes, totalling 1678 pages.
Ancient textiles and clothing in flux
Authors: Jørgensen Lise Bender
Published: October 2019

Textiles and clothing are fundamental aspects of everyday life in the past but are often overlooked in archaeology. Fortunately, this is changing, as witnessed by three new books, reviewed here. Two deal with the beginnings of clothing and textile production, but in different ways; the third contains contributions reflecting on this theme. The monograph by Ian Gilligan—a polyhistory of medicine, psychology, prehistoric archaeology and biological anthropology—presents new theories on the emergence of clothing and textiles in a sustained argument; the two other books, edited volumes comprising 29 papers by textile specialists, each present new research on different aspects of ancient textiles and clothing. In several cases, authors disagree, enhancing the value of the debates, and adding to our understanding of the impact on society of ancient textile production and clothing.
A Highly Contiguous Reference Genome for Northern Bobwhite (Colinus virginianus)
Authors: Salter Jessie F , Johnson Oscar , Stafford Norman J , Herrin William F , Schilling Darren , Cedotal Cody , Brumfield Robb T , Faircloth Brant C
Published: October 2019

Northern bobwhites (Colinus virginianus) are small quails in the New World Quail family (Odontophoridae) and are one of the most phenotypically diverse avian species. Despite extensive research on bobwhite ecology, genomic studies investigating the evolution of phenotypic diversity in this species are lacking. Here, we present a new, highly contiguous assembly for bobwhites using tissue samples from a vouchered, wild, female bird collected in Louisiana. By performing a de novo assembly and scaffolding the assembly with Dovetail Chicago and HiC libraries and the HiRise pipeline, we produced an 866.8 Mb assembly including 1,512 scaffolds with a scaffold N50 of 66.8 Mb, a scaffold L90 of 17, and a BUSCO completeness score of 90.8%. This new assembly represents approximately 96% of the non-repetitive and 84% of the entire bobwhite genome size, greatly improves scaffold lengths and contiguity compared to an existing draft bobwhite genome, and provides an important tool for future studies of evolutionary and functional genomics in bobwhites.
Hacia una nueva educación
Authors: Casas Ulate Ronald , Ovares Barquero Felipe , Rubí Barquero José Alberto
Published: October 2019

Recibido 19 de julio, 2007 • Aprobado 23 de octubre, 2007

 

En este ensayo, centrado en el tema de la Educación, señalamos los principios básicos que configuran el modelo educativo de la era industrial. Para este fin utilizamos los resultados que Alvin Toffler da a conocer en su libro La tercera ola. Estos principios son: uniformización, especialización, sincronización, concentración, maximización y centralización. Tras destacarlos y mostrar cómo cada uno de estos principios deja su impronta en la educación formal del período industrial, defendemos la tesis de que la Nueva educación nace y se configura en un proceso de desmontaje y sustitución por principios del industrialismo por los nuevos principios de la naciente sociedad post-industrial, también llamada Sociedad del conocimiento.
Algunos avances y proyecciones en el campo de la pedagogía rural
Authors: Díaz Alvarado Alicia
Published: October 2019

Recibido 18 de junio 2007 • Aprobado 15 de octubre 2007

 

 

Este artículo explora la forma en que se ha hecho Pedagogía Rural en la División de Educación Rural (DER) del Centro de Investigación y Docencia en Educación (CIDE), de la Universidad Nacional. Para destacar los avances de los últimos tiempos, se organiza este accionar pedagógico en dos grandes momentos, cada uno de ellos con sus características, logros y debilidades. Aunque describe con cierto detalle la forma en que se ha hecho Pedagogía Rural en el camino recorrido por la División, lo importante es destacar cómo esto permite un salto cualitativo hacia nuevos horizontes en la Pedagogía Rural que hace la DER. El artículo finaliza con algunas reflexiones sobre los factores que posiblemente decidirán el destino de la Pedagogía Rural en los ámbitos nacional y centroamericano.
Propuesta de alfabetización de educación no formal, para hombres, mujeres y obreros inmigrantes nicaragüenses
Authors: Núñez Castro Lidieth María
Published: October 2019

Recibido 03 de agosto 2007 • Aprobado 29 de setiembre 2007

 

El artículo resume los principales hallazgos de la investigación realizada sobre el nivel de alfabetización de mujeres y hombres, obreros inmigrantes nicaragüenses, residentes en Costa Rica; específicamente, madres y padres de familia con niños en la Escuela Gonzalo Monge Bermúdez, del distrito de Pital de San Carlos.

En la investigación se determinan los motivos más relevantes por los que algunos nicaragüenses han inmigrado a Costa Rica. Además, se estipulan algunas necesidades a las que ellos desean dar solución en este país, así como el papel que pueden cumplir los procesos de educación no formal en la vida de estas personas.

Es de clara importancia realizar una propuesta de alfabetización en Educación no formal, que permita a mujeres, hombres y obreros inmigrantes nicaragüenses prepararse y formarse para la vida y el trabajo.

De acuerdo con el proyecto para América Latina y el Caribe, programa de Educación Para Todos, la educación es una de las necesidades básicas: Cada persona –niño, joven o adulto– deberá estar en condiciones de beneficiarse de las oportunidades básicas de aprendizaje. Estas necesidades comprenden tanto herramientas esenciales para el aprendizaje (lectura y escritura, problemas de aprendizaje…), como contenidos básicos, requeridos para que los seres humanos sean capaces de sobrevivir, desarrollen sus capacidades, vivan y trabajen con dignidad, participen plenamente en el desarrollo, mejoren la calidad de sus vidas, tomen decisiones fundamentales y continúen aprendiendo.
La participación en el aula escolar rural: un reto para la transformación
Authors: Arguedas Leitón Enid , Núñez Castro Lidieth , Torres Hernández Rodrigo , Vásquez Carvajal Ana Cecilia , Vargas Fallas Claudio Antonio
Published: October 2019

Recibido 11 de setiembre 2007 • Aprobado 20 de noviembre 2007

 

 

Este trabajo analiza el tema de la participación como un medio de ejercer el derecho a la educación, como forma de democratizar el proceso educativo y como vía para lograr pertinencia en el proceso. Se asume, que los padres, madres, estudiantes y otros miembros de la comunidad deben estar cerca de la escuela y aula, no sólo para colaborar con las tareas que tradicionalmente se les asignan a estas personas, sino para desarrollar una nueva forma de participación, que involucre la construcción de los procesos educativos. Para lograr este propósito, los autores y autoras enuncian una serie de estrategias útiles para el acercamiento entre escuela y comunidad.
Participación comunitaria y legislación en El Salvador. Análisis de la legislación identificada
Authors: Cortez Juárez Guillermo
Published: October 2019

Recibido 01 de setiembre 2007 • Aprobado 31 de octubre 2007

 

 

La participación comunitaria es estratégica para lograr efectividad en los procesos de cambio político, económico, social, educativo y cultural; en tanto garantiza la efectividad, calidad y sostenibilidad de las políticas sociales. Por ello, desde la legislación del estado nacional, debe estimularse y promocionarse dicha participación, se dice que siempre ha estado presente, tradicional e históricamente, ha sido impositiva y antidemocrática.

La Educación como acto esencialmente humano, es un instrumento de primer orden que las sociedades deben aprovechar para desarrollar y estimular la participación democrática. Por eso, la educación puede constituirse en una nueva cultura: la de la participación democrática como camino indispensable para el fortalecimiento y desarrollo de la cultura de Paz.
La participación y su viabilidad en Costa Rica
Authors: Arguedas Leitón Enid , Bonilla Houdelatth Erika
Published: October 2019

Recibido 03 de agosto 2007 • Aprobado 20 de noviembre 2007

 

 

Este artículo reflexiona sobre la legislación existente en Costa Rica en lo referente a participación comunal y estudiantil.

Está enfocado en las comunidades rurales, por ser lugares con serias limitaciones, pero a la vez, con grandes potencialidades para el desarrollo.

Se hace necesaria una educación para la participación efectiva del habitante rural, desde sus primeros aprendizajes, para lograr una inserción plena y efectiva de éstos en el mercado nacional y global.
Diagnóstico situacional de la labor docente y de la oferta de formación de educadores rurales en Costa Rica
Authors: Vargas Fallas Claudio Antonio
Published: October 2019

Recibido 11 de setiembre 2007 • Aprobado 20 de noviembre 2007

 

 

El artículo explora la labor de los docentes rurales en Costa Rica y analiza los planes de formación impartidos por las universidades públicas. Indaga sobre las limitaciones y ventajas que tienen quienes ejercen la docencia en las zonas rurales y la manera como enfrentan los retos que les demanda este contexto a partir de sus particularidades culturales, económicas y sociales. Finalmente, a partir de la información recabada por medio de la investigación, presenta una serie de contenidos para que las universidades formadoras de docentes, enriquezcan sus planes de estudio y ofrezcan a sus estudiantes, futuras y futuros docentes, las herramientas necesarias para trabajar en una zona rural.
Una mirada al fenómeno de la violencia escolar en Costa Rica
Authors: Arias Sandoval Leonel
Published: October 2019

Recibido 30 de julio de 2008 • Aprobado 23 de marzo de 2009 • Corregido 20 de abril de 2009

 

En el actual contexto educativo, padres de familia, estudiantes, docentes, medios de comunicación y demás sectores de la sociedad costarricense, manifiestan su preocupación ante el problema de la violencia escolar, fenómeno social que ha venido en aumento en los últimos años. Sus manifestaciones se perciben por medio de conductas de maltrato, intimidación, agresión verbal o física entre jóvenes, y que se construye por medio de prácticas culturales. De ahí que, para comprender este problema, se debe reflexionar acerca de las posibles causas, teniendo en cuenta el contexto en el cual se desarrolla la convivencia social en cada centro educativo. Algunas de las manifestaciones de violencia tienen su origen en la familia, en la comunidad, en la imitación de patrones de conducta y en la influencia de los medios de información de masa. Además, estos comportamientos son potenciados por el modelo curricular vigente, lo que genera resistencia a las normas institucionales.
Componentes teóricos para la comprensión de la pedagogía intercultural como práctica docente
Authors: Artavia Cindy , Cascante Lode
Published: October 2019

Recibido 1º de noviembre de 2007 • Aprobado 15 de marzo de 2008 • Corregido 12 de junio de 2008

 

En la actualidad, un tema que aparece en el ámbito educativo como respuesta a las demandas de una sociedad cada vez más diversa y que exige procesos de inclusión, es, sin duda, el concepto de interculturalidad. Existe una serie de acercamientos conceptuales que distan mucho de crear una pedagogía de la interculturalidad, sobre todo, cuando se valora la interculturalidad como una filosofía, que requiere de un nuevo docente capaz de reciclarse, y que atienda al cambio paradigmático que demanda la interculturalidad.

Este escrito presenta un acercamiento a los componentes teóricos para la comprensión de la pedagogía intercultural como una práctica educativa. Se inicia con una breve presentación de la educación en nuestro tiempo, la interpretación de los derechos humanos como parte fundamental de la diversidad humana, la interculturalidad desde la escuela con los enfoques y los modelos explicativos de esta pedagogía, para, finalmente, abordar de forma breve algunas competencias interculturales de los docentes ante la diversidad.
Multiplicando esfuerzos para fortalecer la familia desde la orientación
Authors: Calderón Monge Eliud , Villalobos Cordero Ana Lucía , Villanueva Barbarán Ruth
Published: October 2019

Recibido 13 de junio de 2008 • Aprobado 23 de marzo de 2009 • Corregido 20 de abril de 2009

 

 

 

La propuesta rescata la sistematización de una experiencia de capacitación a 35 funcionarios y funcionarias docentes y administrativos provenientes de nueve escuelas de Educación General Básica, que se ubican en comunidades con características socioeconómicas desfavorables o de riesgo social. Esta capacitación fue desarrollada por un equipo de dos orientadoras y un orientador, cuyo propósito fundamental fue el facilitar en los y las asistentes, el desarrollo de habilidades que les permitan diseñar y desarrollar actividades en el ámbito de Escuela para padres y madres. Así, se ha modelado una propuesta de trabajo desde la Orientación Educativa, en busca de una mayor cobertura y eficacia de la labor orientadora con la familia desde las escuelas. Se pretende, con ello, promover relaciones familiares saludables que contribuyan al bienestar integral de la familia y, por ende, en el apropiado desenvolvimiento académico y socio afectivo de sus hijos e hijas estudiantes.
Comparison of parameters of the generalized extreme value distribution associated with extreme rainfall events in Central America
Authors: Guillén-Oviedo Helen S. , Cid-Serrano Luis R. , Alfaro-Martínez Eric J.
Published: October 2019

The generalized extreme value distribution (GEVD) was used to model extreme rainfall events in Central America for a period of 30 years, beginning in 1971. Data consisted of daily rainfall records of 103 meteorological stations located throughout the isthmus. Central America was divided into 3 regions: Pacific, Caribbean and an intermediate zone. A bootstrap hypothesis test was used to compare the parameters of location, scale and form of the 3 regions. The results of the study showed significant differences between the 3 regions, mainly in terms of location and scale parameters.
Steady Flow over a Rotating Disk in Porous Medium with Heat Transfer
Authors: Attia H. A. A.
Published: October 2019

The steady flow of an incompressible viscous fluid above an infinite rotating disk in a porous medium is studied with heat transfer. Numerical solutions of the nonlinear governing equations which govern the hydrodynamics and energy transfer are obtained. The effect of the porosity of the medium on the velocity and temperature distributions is considered.
Effect of Peripheral Layer on Peristaltic Transport of a Micropolar Fluid
Authors: Prasad K. M. M. , Radhakrishnamacharya G.
Published: October 2019

Peristaltic transport of two fluid model with micropolar fluid in the core region and Newtonian fluid in the peripheral layer is studied under the assumptions of long wavelength and low Reynolds number. The linearised equations governing the flow are solved and closed form expressions for pressure rise, time averaged flux and frictional force have been obtained. The effects of various parameters on these flow variables have been studied. It is found that the pressure rise increases with micropolar parameter (m) and central mean radius (η), but decreases with coupling number (N) and viscosity ratio (µ¯). The frictional force (F¯) decreases with coupling number (N) and viscosity ratio (µ¯) but increases with micropolar parameter (m) and mean radius of central layer (η).
Numerical Analysis of the Eigenvalue Problem for One-Dimensional Differential Operator with Nonlocal Integral Conditions
Authors: Sajavičius S. , Sapagovas M.
Published: October 2019

In this paper the eigenvalue problem for one-dimensional differential operator with nonlocal integral conditions is investigated numerically. The special cases of general problem are analyzed and hypothesis about the dependence of the spectral structure of that problem on the coefficient of differential operator and the parameters of nonlocal conditions are formulated.
Effect of Time-Delay on a Ratio-Dependent Food Chain Model
Authors: Patra B. , Maiti A. , Samanta G. P. P.
Published: October 2019

This paper aims to study the effect of time-delay on a tritrophic food chainmodel with Michaelis-Menten type ratio-dependent functional responses. Boundednessof the time-delayed system is established. A simple criterion for deterministic extinctionis derived. It has been shown that the time-delay may introduce instability in the systemthrough Hopf bifurcation. Computer simulations are carried out to explain the analyticalfindings. It is discussed how these ideas illuminate some of the observed properties ofreal populations in the field, and explores practical implications.
Estimation of a Distribution function under Sampling on Two Occasions
Authors: Chadyšas V.
Published: October 2019

Estimation of the distribution function under sampling on two occasions with a simple random sampling design on each occasion is investigated. Composite regression and ratio type estimators are considered, using values of the study variable as auxiliary information obtained on the first occasion. The optimal estimator, in the sense of minimal variance, is also obtained. A simulation study, based on the real population data, is performed and the proposed estimators are compared by a simple estimator for a distribution function.
Local Hopf Birurcation and Stability of Limit Cycle in a Delayed Kaldor-Kalecki Model
Authors: Kaddar A. , Talibi Alaoui H.
Published: October 2019

We consider a delayed Kaldor-Kalecki business cycle model. We first consider the existence of local Hopf bifurcation, and we establish an explicit algorithm for determining the direction of the Hopf bifurcation and the stability or instability of the bifurcating branch of periodic solutions using the methods presented by O. Diekmann et al. in [1]. In the end, we conclude with an application.
Saddlestrapping
Authors: Singh Sarjinder
Published: October 2019

A method of weighted bootstrapping in the presence of auxiliary information has been studied and named as saddlestrapping because there exists a saddlepoint. Comparisons of saddlestrapping with the bootstrapping under different situations are performed and discussed. FORTRAN code for doing bootstrapping and saddlestrapping are provided. A huge scope of further studies has been suggested.
On the Sojourn Time of the Brownian Process in a Multidimensional Sphere
Authors: Steišūnas S.
Published: October 2019

We consider the Brownian motion process Bm(s) in the m-space and the distribution
Fm(t, x, a) = P{sup0 ≤ s ≤ t|Bm(s) + ∞| < a}, where a > 0, x ∈ Rm, |x| < a.
There is a probability that a particle starting from the point x on the sphere Srm with the radius r = |x| < a will not be absorbed by the sphere Sam with a radius a before the epoch t.
Global Existence of Periodic Solutions in a Delayed Kaldor-Kalecki Model
Authors: Kaddar A. , Talibi Alaoui H.
Published: October 2019

This paper is concerned with a delayed Kaldor-Kalecki non-linear business cycle model in income. By applying a global Hopf bifurcation result due to Wu, the global existence of periodic solutions is investigated. Numerical examples will be given in the end, to illustrate our theoretical results.
TEXTURE PROFILE ANALYSIS (TPA) OF ORGANIC SWEETPOTATO (IPOMOEA BATATAS) CULTIVARS AS AFFECTED BY DIFFERENT PROCESSING METHODS
Authors: Nwosisi Sochinwechi , Nandwani Dilip , Ravi Ramasamy
Published: October 2019

Almost one-third of the entire U.S. is buying organic produce. It is believed that organic foods taste better and are more nutritious than conventional foods. To develop successful market positioning, the characteristics desirable to consumers, for sweetpotato must be identified. Different processing methods particularly thermal treatments would impact sweetpotato textures differently and as such affect the consumer liking and eventually product acceptability. Clear understanding of the influence of different thermal treatments on the textural characteristics of sweetpotato is therefore needed. The major objective of this research work was to evaluate the impact of different thermal processing techniques such as baking, pressure cooking, and open cooking on the textural characteristics of sweetpotato cultivars. Six cultivars of sweetpotato grown on a certified organic farm were subjected into different thermal treatments. Baking was done using an air oven for 60 min. Pressure cooking was done using a pressure cooking for 15 min and open cooking was done using a vessel filled with water (500 ml) for 1 hour. In all thermal treatments, the inside product temperature was kept constant (60±2°C). The texture parameters were recorded with a texture analyzer using a 100 mm dia probe. The samples were also penetrated 5 mm from the surface using a needle probe of 2 mm dia. Maximum peak force was set in Newtons. Across the treatments, open cooked Japanese Purple was found to be the hardest although not significantly different from Hernandez open cooked cultivar. Baked Old Yellow sweetpotato was the most gummy and chewy while the softest cultivar was the pressure cooked Old Yellow; however it did not differ significantly from the other five cultivars tested.
THE QUALITY OF HONEYS INFLUENCED BY THE TRADITIONAL HEATING METHOD
Authors: Haouam Lynda , Dailly HÃ©lÃ¨ne , Bruneau Etienne , Tahar Ali
Published: October 2019

In this study, three parameters (hydroxymethylfurfural, diastase activity and invertase activity) were used to evaluate the quality of twenty samples of multifloral honey from northern Algeria heated by a traditional method (conventional heating in a water bath at 100 °C) for five treatment periods (2, 4, 6, 8 and 16 min). The assay was carried out with honey samples whose initial HMF, diastase activity and invertase activity values were within the recommended food authority limit. HMF was determined by HPLC, diastase was measured with Phadebas and invertase was determined using the Siegenthler method. During heating, it was observed an increase in the HMF related to an increase in temperature, but still below the international standard limit (40 mg.kg-1). Diastase activity and invertase activity also decreases during heating. However, invertase is more heat-sensitive and heating time than diastase and HMF, and it's an important parameter to determine if honey has been submitted to heating. Therefore to liquefy honey we can use this method but with a low temperature and a short time because time has a deep impact on the quality of heating treatment of honey.
CHEMICAL COMPOSITION, ANTIOXIDANT ACTIVITY AND MINERAL CONTENT OF ARBUTUS UNEDO (LEAVES AND FRUITS)
Authors: Asmaa Noureddine , Abdelaziz Gherib , Boulanouar Bakchiche , A. Carbonell-Barrachina Ãngel , Cano-Lamadrid Marina , Noguera-Artiaga Luis
Published: October 2019

Arbutus unedo is widely used in traditional medicine and is an easily accessible source of natural antioxidants to replace synthetic antioxidants. The bioactive compounds and antioxidant activity of the leaves and fruits extracts (after maceration and sonication) were studied. The mineral analyses exhibited large quantities of many essential minerals in fruits and leaves, especially interesting were the levels of macronutrients (K and Ca) in fruits and micronutrients (Fe) in leaves. The GC–MS analysis of essential oils of leaves and fruits led to the identification of 32 and 35 compounds, respectively. The major components in leaves were camphor, cymenene, and bornyl acetate, and in fruits, camphor, ethyl palmitate and bornyl acetate. The extraction method significantly affected the contents of total phenolics and total flavonoids, with the maceration method rendering the best results in leaves and the sonication in fruits. All maceration extracts had the highest antioxidant activity (assayed by 3 methods DPPH•, ABTS+ and FRAP; besides, A. unedo leaves showed higher activity than fruits. As a conclusion, it can be stated that Arbutus unedo is a plant rich in polyphenols, volatile compounds, and minerals, and that it can be used as a potential source of bioactive compounds, especially from the leaves
Contribuições agostinianas ao conceito de pessoa humana: problemas da ipseidade e da interpessoalidade
Authors: Paolozzi Mariana
Published: October 2019

O tema da pessoa humana em Agostinho apresenta-se entrelaçado à noção depessoa divina, de onde deriva. Buscaremos contextualizá-lo abordando alguns de seus desenvolvimentos, com ênfase nas questões da ipseidade (singularidade) e da interpessoalidade. Assim, inicialmente, será examinado o significado da pessoa humana, sob o ponto de vista da ipseidade, conforme o problema surge no l. VII do De Trinitate. Será destacada a questão dos universais e a interlocução de Agostinho com a lógica aristotélica. Em seguida, será abordada a questão da interpessoalidade; aqui, levanta-se uma oposição à tese de que há em Agostinho um certo esquecimento do “ser em relação” em detrimento da ideia de comunhão e da importância das relações interpessoais na gênese do “eu”. Em suma, pretende-se apontar como a ideia de “pessoa” em Agostinho exprime, quer a individualidade (no sentido de ipseidade),  quer a relacionalidade. Os medievais e os contemporâneos irão trabalhar com essas noções e as desenvolverão sob o influxo do pioneirismo e do contributo agostiniano.
Cícero, Aquino e temas jusnaturalistas contemporâneos
Authors: Seagrave Adam
Published: October 2019

Tradução de Bruno Rodrigo D'ambros.
Axel Honneth e a sua teoria plural da justiça
Authors: Fontes Paulo Vitorino
Published: October 2019

Axel Honneth desenvolve o conceito de reconhecimento, encarado como uma necessidade fundamental do ser-humano, de forma a constituir-se no núcleo de uma teoria da justiça que procura especificar as condições intersubjetivas de autorrealização individual. Apresenta-se uma teoria da justiça assente na reconstrução das práticas e condições de reconhecimento já institucionalizadas, analisando as instituições sociais em um sentido amplo. Pretende-se aproximar a concepção normativa da justiça da análise sociológica das sociedades modernas, através da reconstrução normativa e ao colocar a ênfase na liberdade social, baseada na dimensão intersubjetiva das instituições de reconhecimento. A liberdade social prevê o acesso às instituições de reconhecimento. Um dos objetivos é esboçar os problemas desse avanço interpretativo da teoria crítica do reconhecimento, pelo que iremos convocar a teoria da luta pelo reconhecimento  de Honneth, incluir a sua reactualização mais recente do Direito de Hegel e explorar a sua proposta normativa para as condições de uma vida ética.
From Social Conflicts to Human Rights: The Normative Meaning of Human Rights in Rainer Forst
Authors: Sell Jorge Armindo
Published: October 2019

Universal Declaration of Human Rights (UDHR) 70th anniversary is been celebrated in 2018. On the other hand, people are still arguing about the political, juridical, social and civilizational gains it has provided. Such discussions, however, focus on peripheral aspects of Human Rights, losing sight of what could be understood as its highest normative gain. Whenever arguments are not completely rectified, they dissociate from the social demands that actually gave them meaning and relevance. From this scope, the article intends to reconstruct the conceptual and argumentative aspects of Human  Rights from the critical theory of relations of justification by Rainer Forst, in which Human Rights are interpreted as arising from a fundamental right to justification. This fundamental right, in Forst’s theory, is interpreted as being part of the “deep grammar” of social conflicts. According to the Forstian theory, we argue for an interpretation of Human Rights capable of encompassing the multiple aspects of these rights, avoiding reductionism and unilateral interpretations of it. This presentation has been divided into three parts. First, it presented some traditional “pictures”, current forms of referring to Human Rights and its characteristics, against which another picture will be proposed, in order to place social conflicts and rejections of injustice as a starting point for the Human Rights. Next, the Forst’s principle of justification and the recursive argument that led toit was discussed. Finally, a critical interpretation of the Forstian proposal, which dealtwith the purposes that his theory is allegedly seeking, was carried out.
Direito, intersubjetividade e Estado em Edith Stein
Authors: Pereira Ponzilacqua Marcio Henrique
Published: October 2019

O objetivo do artigo é compreender e apresentar a filosofia do direito no âmbito do pensamento de Edith Stein. Sob o prisma fenomenológico, há de se analisar os conceitos axiais empregados pela autora, capazes de elucidar o sentido de direito, tais como Pessoa, Comunidade e Estado, conforme defluem de seus escritos e refletivos à luz de especialistas. Com base nesses elementos, há de se perscrutar a atualidade e aplicação do seu pensamento no contexto sociojurídico contemporâneo e as possíveis consequências desta aferição. Há também de se ponderar e refletir os paradigmas hegemônicos na ciência jurídica mediante às contribuições peculiares da autora. Os resultados da  análise permitem entrever a densidade dos textos de Stein, cujos aportes filosóficos podem orientar hermenêutica jurídica consistente, mediante percepção metanormativa.
Giorgio Agamben, creazione e anarchia. L’opera Nell’età della religione capitalista, neri pozza, Vicenza 2017, p. 140, € 12.50, isbn 9788854515604
Authors: Junges Márcia Rosane
Published: October 2019

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Emoção, juízo moral e razão: Damásio e a crítica do racionalismo ético
Authors: De Lima Francisco Jozivan Guedes , De Oliveira Nythamar Hilario
Published: October 2019

Trata-se de mostrar, à luz da teoria das emoções de António Damásio, em que sentido “o erro de Descartes” traduz um equívoco do racionalismo ético na medida em que despreza o papel do corpo, da matéria e das paixões para a aquisição e o florescer  de uma vida virtuosa no campo da filosofia moral ou mesmo para um conhecimento indubitável no campo epistemológico.
Guettarda sierrae (Rubiaceae), a new species from the NE coast of Cuba and lectotypification of Guettarda undulata
Authors: González G. P. A. , Gómez H. J. L.
Published: October 2019

Guettarda sierrae, a new species from the NE coastal fringe of Cuba, is described and compared with other species of the genus occurring in Cuba. Aspects of its distribution and conservation status are discussed. A lectotype for Guettarda undulata, a Cuban species related to Guettarda sierrae, is proposed herein.
New and noteworthy lichen-forming and lichenicolous fungi 9
Authors: Kondratyuk S. Y. , Lőkös L. , Farkas E. , Jang S.-H. , Liu D. , Halda J. , Persson P.-E. , Hansson M. , Kärnefelt I. , Thell A. , Fačkovcová Z. , Yamamoto Y. , Hur J.-S.
Published: October 2019

The new for science genus Loekoeslaszloa S. Y. Kondr. et J.-S. Hur, confirmed by three gene phylogeny of the subfamily Teloschistoideae of the Teloschistaceae based on nrITS, nrLSU and mtSSU sequences, and ten new to science species from Eastern Asia, i.e. from South Korea: Bacidina loekoesiana S. Y. Kondr. et J.-S. Hur, Fauriea jejuensis S. Y. Kondr., L. Lőkös et J.-S. Hur, Gyalecta ulleungdoensis S. Y. Kondr., L. Lőkös et J.-S. Hur, Loekoeslaszloa huriana S. Y. Kondr., Orientophila dodongana S. Y. Kondr., L. Lőkös et J.-S. Hur, O. imjadoensis S. Y. Kondr., L. Lőkös et J.-S. Hur, O. incheonensis S. Y. Kondr., L. Lőkös et J.-S. Hur, Oxneriopsis taehaensis S. Y. Kondr., L. Lőkös et J.-S. Hur, Yoshimuria ivanpisutiana S. Y. Kondr., L. Lőkös et J.-S. Hur and Y. seokpoensis S. Y. Kondr., L. Lőkös et J.-S. Hur are described, illustrated and compared with closely related taxa.

Molecular data for the recently described species Flavoplaca laszloana are for the first time provided. Position of Tassiloa magellanica in the subfamily Teloschistoideae as well as Yoshimuria stipitata in the Ikaerioideae ad int. is for the first time illustrated.

An identification key to Fauriea species (including six species, i.e.: F. chujaensis, F. jejuensis, F. orientochinensis, F. patwolseleyae, F. tabidella and F. yonaguniensis), a key to Orientophila species of the Eastern Asian region (of the Orientophila loekoesii and the O. diffluens groups), and a key to Yoshimuria and Loekoeslaszloa species of the Eastern Asian region (including four species, i.e.: Y. galbina, Y. ivanpisutiana, Y. seokpoensis, and Y. spodoplaca, as well as Loekoeslaszloa geumohdoensis and L. huriana) are presented. Seven new combinations, i.e. Fauriea patwolseleyae (basionym: Caloplaca patwolseleyae S. Y. Kondr., U. Jayalal et J.-S. Hur), Fauriea tabidella (basionym: Lecanora tabidella Nyl.), Loekoeslaszloa geumohdoensis (basionym: Mikhtomia geumohdoensis S. Y. Kondr., D. Liu et Hur), Niesslia coarctatae (basionym: Stigmidium coarctatae S. Y. Kondr., L. Lőkös et J.-S. Hur), Opeltia epiphyta (basionym: Caloplaca epiphyta Lynge), Tassiloa magellanica (basionym: Caloplaca magellanica Søchting et Sancho) and Yoshimuria stipitata (basionym: Caloplaca stipitata Wetmore) are proposed. Yoshimuria galbina and Lecanora ussuriensis are for the first time recorded from Japan.
Rivers of Knowledge
Authors: Nunn Patrick
Published: October 2019

Ancient stories recalling memorable events can be demonstrated as enduring in recognizable form in oral (non-literate or pre-literate) cultures for several millennia. As explained in the author’s 2018 book, The Edge of Memory (Bloomsbury, London), some of the most compelling of these stories are those recalling coastal ‘drowning’, interpreted in most instances as recalling the rise of sea level following the end of the last Ice Age; some of these stories from Aboriginal Australia can be given minimum ages of 7000-10,000 years ago. Examples are also given of ancient stories from Australia and elsewhere that recall volcanic eruptions and meteorite falls, both of which can be dated with some degree of certainty. This paper extends the arguments in The Edge of Memory to an analysis of stories that appear to recall people’s responses to rising sea level more than seven millennia ago and allow insights into their thinking. It seems clear that today, confronted by a similar phenomenon, we can learn from the actions of our distant ancestors.
Effect of Y addition on microstructure and mechanical properties of extruded Mg–Mn alloys
Authors: Luo Xiaoping , Fang Daqing , Kang Li
Published: October 2019

Two homogenized as-cast magnesium (Mg)–1 wt% manganese (Mn) alloys containing 1·0 and 4·0 wt% alloying yttrium (Y) were processed at an extrusion ratio of 17:1 at 400°C using a ram speed of 0·3 mm/s. The effect of yttrium additions on the microstructure and mechanical properties of the extruded alloy was analyzed and compared. The average grain size of the extruded Mg–1Mn–4Y (MW14) alloy was much smaller than that of the extruded Mg–1Mn–1Y (MW11) alloy. In addition, the tensile strength of the MW14 alloy was higher than that of the MW11 alloy at the investigated temperature ranging form RT to 200°C, although the former exhibited a lower elongation to failure. The fracture surface of the MW14 alloy exhibited the cleavage fracture mode. Conversely, a dimple was observed in the MW11 alloy which the significant differences in performance between the two alloys are attributed to their Y contents.
Methionine and Glycine Stabilize Mitochondrial Activity in Sake Yeast During Ethanol Fermentation
Authors: Jannatul Ferdouse , Kusaba Yuki , Fujimaru Yuki , Yamamoto Yuki , Kitagaki Hiroshi
Published: October 2019

Addition of amino acids to fermentation media affects the growth and brewing profiles of yeast. In addition, retaining mitochondrial activity during fermentation is critical for the fermentation profiles of brewer’s yeasts. However, a concrete mechanism linking amino acids in fermentation media with mitochondrial activity during fermentation of brewer’s yeasts is yet unknown. Here, we report that amino acids in fermentation media, especially methionine (Met) and glycine (Gly), stabilize mitochondrial activity during fermentation of sake yeast. By utilizing atg32Δ mutant sake yeast, which shows deteriorated mitochondrial activity, we screened candidate amino acids that strengthened the mitochondrial activity of sake yeast during fermentation. We identified Met and Gly as candidate amino acids that fortify mitochondrial activity in sake yeast during fermentation. To confirm this biochemically, we measured reactive oxygen species (ROS) levels in sake yeast fermented with Met and Gly. Yeast cells supplemented with Met and Gly retained high ROS levels relative to the non-supplemented sake yeast. Moreover, Met-supplemented cells showed a metabolome distinct from that of non-supplemented cells. These results indicate that specific amino acids such as Met and Gly stabilize the mitochondrial activity of sake yeast during fermentation and thus manipulate brewing profiles of yeast.
ÖĞRETMENLERİN GÖRÜŞLERİNE GÖRE ÖĞRETMENLİK MESLEĞİNİN İMAJI: BİR ÖLÇEK GELİŞTİRME VE UYGULAMA ÇALIŞMASI
Authors: DOĞAN Özcan , BAYRAK Coşkun
Published: October 2019

Bu araştırma, öğretmenlik
mesleğinin imajını ortaya çıkarmaya yönelik bir ölçek geliştirme ve uygulama
çalışmasıdır. Araştırma kapsamında öğretmenlik mesleğinin imajını ölçecek
geçerli ve güvenilir bir ölçme aracı geliştirmek ve bu ölçek ile öğretmenlerin görüşlerine
göre öğretmenlik mesleğinin imajını ortaya çıkarmak hedeflenmiştir. “Öğretmenlik
mesleği imaj ölçeği” olarak adlandırılan ölçek beş boyuttan ve 28 maddeden
oluşmaktadır. Ölçek toplam varyansın %54,9’unu açıklamaktadır ve Cronbach Alpha değeri ,813 olarak hesaplanmıştır. Ölçeğin
Eskişehir ilinde daha büyük bir örnekleme uygulanması ile elde edilen sonuçlara
göre öğretmenler, öğretmenlik mesleğinin imajının orta düzeyde olduğunu;
“mesleki ve kişisel özellikler”, “mesleki cazibe” ve “statü” boyutlarında
meslek imajının iyi düzeyde olduğunu; “toplumsal algı” ve “medya” boyutlarında
ise düşük düzeyde olduğunu belirtmektedirler. Bu sonuçlara göre mesleğin
imajının iyileştirilmesine yönelik ve toplumsal algıyı iyileştirecek çalışmalar
yapılması önerilmiştir.