bluuebunny/crossref_metadata_2025 huggingface dataset:
Femicidio y emociones en la Argentina rosista: el caso de Paulino Rojas y Encarnación Fierro
Authors: Miseres Vanesa
Published: April 2021

La violencia de género y el femicidio conforman el centro de los debates actuales en torno al feminismo y han sido, sin duda, uno de los principales ejes de movilización pública y política en la última década en la Argentina y en el resto de Latinoamérica. Este artículo propone una mirada histórica sobre el tratamiento y la visibilidad social de ambos términos (violencia de género y femicidio) a partir del estudio de un caso particular del siglo XIX argentino: el del militar Paulino Rojas, integrante del Regimiento de Granaderos a Caballo y partícipe de la campaña libertadora del Perú, y el juicio al que se lo sometiera por ser el principal sospechoso de la muerte de su esposa, Encarnación Fierro. El caso de Rojas y Fierro es un ejemplo clave para entender las relaciones, jerarquías y alianzas interpersonales (militares, amorosas, familiares, de amistad) del período rosista, el valor de las emociones en la construcción de los sujetos en el siglo XIX y el impacto de las mismas en el ejercicio de la ciudadanía y los derechos, aún en pugna, de las mujeres.
Imaginarios de amistad, autoría y deseo: la figura de la escritora en la prensa argentina de 1880
Authors: Vicens María
Published: April 2021

Este artículo analiza el imaginario que se construyó en torno a la figura de la escritora en la prensa argentina para mujeres de 1880 y cómo este mundo de afectos idealizados y feminizados muestra sus fisuras en las secciones “subalternas” de esas publicaciones. En sus columnas de moda, de crónica social y misceláneas, circulan emociones y gestualidades anti-normativas para el “deber ser” femenino de la época (gritos, enojos, reclamos, pero, también, deseos y ambiciones) que operan como doblez de esa comunidad afectiva, abriendo el espacio de la prensa a nuevas voces y tonos femeninos.
Enhancing Company Financial Transparency for Contractor Selection Process through XBRL: A Conceptual Framework
Authors: Abd Wahab Zulkarnain , Shavarebi Kamran
Published: April 2021

Amongst the predicament in selecting a contractor for project implementation is to identify a resilient partner who can withstand the financial impact posed by project risks and constraints. For that matter, decision-makers require full transparency of financial information of the candidates for an effective contractor selection process. In the context of Malaysia, authorities are adopting Extensible Business Reporting Language (XBRL) to convey information about companies financial standing. This study is aimed to develop a conceptual framework in utilising the increase of information brought along by XBRL implementation to facilitate transparency as required by decision-makers during the contractor selection process. This article is also articulating on factors to promote adoption of online business reporting to increase information integrity, recency and contextually to increase the transparency.
Can diagnostic accuracy for early glaucoma be improved in Japanese? A trial with a potential new parameter of the RTVue OCT
Authors: Kita Yoshiyuki , Hollό Gábor , Kita Ritsuko
Published: April 2021

Aim: To evaluate the diagnostic accuracy of the ratio of circumpapillary retinal nerve fiber layer thickness (cpRNFLT) to macular outer retinal thickness (R/O ratio) and the ratio of ganglion cell complex (GCC) thickness to outer retinal thickness (G/O ratio) measured with the RTVue-100 Fourier-domain optical coherence tomograph for detecting early glaucoma in Japanese eyes.Methods: Forty-seven healthy control, 31 preperimetric and 70 early perimetric glaucoma eyes. We used cpRNFLT and macular retinal thickness measurements to calculate new ratio parameters, and to compare their diagnostic accuracy to those of the manufacturer-provided parameters of the RTVue-100. The ability of each parameter to diagnose glaucoma was examined by comparing the area under the receiver-operating characteristics curve (AUROC).Results: AUROC values for the healthy vs. preperimetric glaucoma comparison were 0.842, 0.859, and 0.925 for average cpRNFLT, average R/O ratio, and average G/O ratio, respectively. For the healthy vs. early perimetric glaucoma comparison the AUROC values were 0.927, 0.933, and 0.979 for cpRNFLT, R/O ratio, and G/O ratio, respectively. Diagnostic accuracy of the R/O ratio and cpRNFLT did not differ significantly (P > 0.05). Diagnostic accuracy for the G/O ratio was significantly greater than the cpRNFLT in early glaucoma (P < 0.05).Conclusions: Use of the G/O ratio is recommended for the detection of early glaucoma in Japanese eyes.
Modeling autoregulation in three-dimensional simulations of retinal hemodynamics
Authors: Aletti Matteo , Gerbeau Jean-Frédéric , Lombardi Damiano
Published: April 2021

Purpose: Autoregulation is a mechanism necessary to maintain an approximately constant blood flow rate in the microcirculation when acute changes in systemic pressure occur. Failure of autoregulation in the retina has been associated with various diseases, including glaucoma. In this work, we propose an initial attempt to model autoregulation in a 3D network of retinal arteries.Methods: The blood flow is modeled with the time-dependent Stokes equations. The arterial wall model includes the endothelium and the smooth muscle fibers. Various simplifying assumptions lead to a fluid-structure model where the structural part appears as a boundary condition for the fluid. The numerical simulations are performed on a patient-specific network of 25 segments of retinal arteries located in the inferior temporal quadrant.Results: The simulations performed on the patient-specific artertial network have provided velocities which are in good agreement with published experimental data. In addition, the model allowed to reproduce flow rate-pressure curves which are comparable with experimental data or results obtained with 0D models. In particular, a characteristic plateau of the flow rate has been found for pressures ranging from 40 to 60 mmHg.Conclusion: This work proposes the first 3D simulation of blood flow in a real network of retinal arteries and it also incorporates an autoregulation mechanism. This can be viewed as a first step towards a more complete 3D model of the hemodynamic of the eye.
Potent and selective antisense oligonucleotides targeting the transforming growth factor beta (TGF-β) isoforms in advanced glaucoma: a preclinical evaluation
Authors: Hasenbach Kathy , Van Bergen Tine , Vandewalle Evelien , De Groef Lies , Van Hove Inge , Moons Lieve , Stalmans Ingeborg , Fettes Petra , Leo Eugen , Wosikowski Katja , Janicot Michel
Published: April 2021

Purpose: ISARNA Therapeutics is developing highly potent and selective LNA-modified ASO gapmers targeting TGF-β1 and TGF-β2 mRNA. In the field of ophthalmology, glaucoma, the second leading cause for blindness in the US, has been linked to TGF-β activation as a key driver. ISTH0036 is a 14-mer phosphorothioate Locked Nucleic Acid- (LNA) modified antisense oligonucleotide gapmer, targeting the sequence of TGF-β2 mRNA and was developed for therapeutic intervention in ocular diseases. It was shown to effectively and potently downregulate target mRNA in a dose-dependent manner in relevant cell-based assays, as well as leading to target engagement in anterior eye segment tissues upon intravitreal administration (Isarna proprietary information). The aim of this study was to evaluate the therapeutic potential of ISTH0036 in murine models of glaucoma filtration surgery (GFS) following different intraocular administrations.Methods: A murine model of glaucoma filtration surgery has been used to evaluate the effect of intraocular ISTH0036 administration on post-operative wound healing. Bleb size and bleb survival were determined after different intraocular administrations of saline, control scrambled oligonucleotide or ISTH0036 (at day of surgery and after two weeks).Results: Intraocular administrations of ISTH0036 lead to a significant effect on bleb area and survival, as well as decreasing scarring (downregulation of collagen-1 and -3 fibers) in a murine glaucoma filtration surgery model.Conclusion: Consistent with the expected molecular mechanism of action and demonstrated pharmacokinetic (PK) and pharmacodynamic (PD) properties following intraocular administration, preclinical data with ISTH0036 in murine glaucoma filtration surgery model support the current exploration of the drug candidate in advanced glaucoma patients undergoing trabeculectomy.
Equilibrium shape of the aqueous humor-vitreous substitute interface in vitrectomized eyes
Authors: Isakova Krystyna , Pralits Jan O. , Romano Mario R. , Beenakker Jan-Willem M. , Shamonin Denis P. , Repetto Rodolfo
Published: April 2021

Purpose: To predict the shape of the interface between aqueous humor and a tamponade, gas or silicone oil (SO), in vitrectomized eyes. To quantify the tamponated retinal surface for various eye shapes, from emmetropic to highly myopic eyes. Methods: We use a mathematical model to determine the equilibrium shape of the interface between the two fluids. The model is based on the VOF (volume of fluids) method. The governing equations are solved numerically using the free software OpenFOAM. We apply the model both to the case of idealized, yet realistic, geometries of emmetropic and myopic eyes and to a real geometry reconstructed from MRI images of the vitreous chamber. Results: The numerical model allows us to compute the equilibrium shape of the interface between the aqueous humor and the tamponade fluid. From this we can compute the portion of the retinal surface that is effectively tamponated by the fluid. We compare the tamponating ability of gases and SOs. We also compare the tamponating effect in emmetropic and myopic eyes by computing both tamponated area and angular coverage. Conclusion: The numerical results show that gases have better tamponating properties than SOs. We also show that, for a given filling ratio the percentage of tamponated retinal surface area is smaller in myopic eyes. The method is valuable for clinical purposes, especially in patients with pathological eye shapes, to predict the area of the retina that will be tamponated for a given amount of injected fluid.
Correlation and agreement between the 24-hour diurnal tension curve, the water-drinking test, and the postural-change test in glaucoma patients
Authors: Goncalves Fauze A. , Amorim Fernando Henrique R. , Zangalli Camila S. , Vasconcellos Jose Paulo C. , Costa Vital P.
Published: April 2021

Aim: To investigate whether the water-drinking test (WDT) and the postural-change test (PCT) can predict the 24-hour diurnal tensional curve (DTC) intraocular pressure (IOP) peak and fluctuation by assessing the correlation and agreement between these three tests in medically treated primary open-angle glaucoma (POAG) patients.Methods: 18 POAG patients underwent the DTC, WDT and PCT. Pearson’s correlation coefficient and Bland-Altman plots were used to assess the correlation and agreement between the results, respectively.Results: Mean DTC IOP peak was 18.72 + 4.31 mmHg and mean DTC IOP fluctuation was 7.00 + 2.54 mmHg. The IOP peak was outside office hours in 50% of the subjects. We observed poor correlations between the DTC and WDT fluctuations and the DTC and PCT fluctuations (r=-0.125, P=0.619; r=0.349, P=0.155, respectively). There was a moderate positive correlation between the DTC and WDT peaks (r=0.493, P=0.03) and a strong positive correlation between the DTC and PCT peaks (r=0.722, P<0.001). However, Bland-Altman plots demonstrated poor agreement between the IOP peaks and fluctuations between the 3 tests. WDT and DTC IOP peaks differed by 2 mmHg or more in 56% of the measurements. PCT and DTC IOP peaks showed that 83% of the measurements had differences greater than 2 mmHg.Conclusions: Despite moderate to strong correlations between DCT and WDT peaks and DTC and PCT IOP peaks, the agreement was generally poor, suggesting that they should be used with caution to estimate peak IOP.
Hemodynamic parameters and vessel tortuosity: an investigation with a mesenterial vascular network
Authors: Annunziata Roberto , Reglin Bettina , Pries Axel , Trucco Emanuele
Published: April 2021

Purpose: The effect of hemodynamic parameters on vessel tortuosity remains un-clear. Here we investigate the correlation of tortuosity with a set of hemodynamicparameters in a mesenterial vascular network.Methods: A mesenterial vascular network of 389 vessels (131 arteries, 132 veins, and 126 capillaries) was imaged. Eleven hemodynamic parameters were measured (pressure, wall shear stress, diameter, blood velocity and flow, viscosity, haematocrit, partial oxygen saturation, oxygen saturation, wall thickness, and local vessel density). Tortuosity was assessed quantitatively with a validated algorithm and correlation computed with subsets of hemodynamic parameters selected by a lasso regressor.Results: Results suggest that tortuosity is related to pressure, wall shear stress, diameter, blood velocity, viscosity, partial but not full oxygen saturation, and wall thickness for the arteries; diameter, blood flow, hematocrit, and density for the veins; and viscosity (but not hematocrit), partial and full oxygen saturation, and density for the capillaries. The combination of hemodynamic parameters correlating best with tortuosity is the set of all parameters except density (r = 0.64, p < 0.01), using as tortuosity definition the set of tortuosity features (geometric measures) correlating best with a single hemodynamic factor for the arteries.Conclusion: This pilot suggests two general conclusions. First, the quantitative definition of tortuosity (i.e., the set of geometric features adopted) should be tuned to the specific data and problem considered. Second, tortuosity is caused by a combination of hemodynamic factors, not a single one.
ARVO 2017 highlights in mathematical modeling
Authors: Braun Richard J
Published: April 2021

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Clinical assessment of intraocular pressure: a whole-eye dynamic model
Authors: Stefanoni Francesca , Harris Alon , Szopos Marcela , Prud’homme Christophe , Sacco Riccardo , Messenio Dario , Costantino Maria Laura , Guidoboni Giovanna
Published: April 2021

The aim of this work is to provide a quantitative description of how geometrical and material properties of ocular tissues and fluids influence intraocular pressure (IOP).
Multiscale modeling and simulation of neurovascular coupling in the retina
Authors: Sacco Riccardo , Mauri Aurelio G. , Cardani Alessandra , Siesky Brent A. , Guidoboni Giovanna , Harris Alon
Published: April 2021

The role of nitric oxide (NO), usually considered as a potent vasodilator, in regulating retinal neurovascular coupling is still elusive. Measurements of flicker light-induced functional hyperemia (FH) in humans show that an increase of NO levels reduces vasodilation. This evidence has led to conjecture that such an increase may be responsible for suppressing flicker-evoked vasodilation in diabetic retinopathy. In this paper, we propose a mathematical model to theoretically investigate the effect of an increase in neural NO (nNO) on the vasodilation of retinal arterioles. Simulation results indicate that nNO increase may:1. significantly aff ect vasoconstrictive agent production by glial cells; and2. elicit vasoconstriction rather than vasodilation in retinal arterioles.Model predictions seem therefore to support the conjecture that NO increase may be responsible for suppressing flicker-evoked vasodilation in diabetic retinopathy.
Editorial ESB-ITA 2017 special issue
Authors: Pandolfi Anna , Vairo Giuseppe
Published: April 2021

This special issue of the Journal for Modeling in Ophthalmology collects, in the form of extended abstracts, contributions presented during the Thematic Symposium on Eye Biomechanics, organized within the VII Annual Meeting of the Italian Chapter of the European Society of Biomechanics (ESB-ITA 2017) held on September 28-29, 2017 in Rome, Italy. The scientific and administrative organization of the general meeting was committed to the Università degli Studi di Roma “Tor Vergata”, while the scientific coordination of the thematic symposium was assigned to the Politecnico di Milano.
Influence of benzalkonium chloride on tear film lipid layer stability: a molecular level view by employing in silico modeling
Authors: Riedlova Kamila , Melcrova Adela , Olzynska Agnieszka , Daull Philippe , Garrigue Jean-Sebastien , Cwiklik Lukasz
Published: April 2021

Benzalkonium chloride (BAK) is a mixture of aliphatic C12 and C14 quaternary ammoniums. These molecules are traditionally used to preserve eye drops because of their bactericidal and bacteriostatic properties. The compounds of BAK have an amphiphilic character, hence it can be assumed that on the ocular surface they can interact and alter the properties of the tear film lipid layer (TFLL). Indeed, BAK was demonstrated to decrease the breakup time in patients, which is a hallmark of TFLL destabilization. The amphiphilic and water-soluble C12 and C14 BAK molecules are expected to act predominantly at the aqueous-lipid interface that, as we have demonstrated earlier, is populated mostly by polar lipids.7,8 Notably, these BAK species are short-chain analogues of cetalkonium chloride (CKC) that, as we have shown previously, interact with the TFLL model, improving its stability. We hypothesize that by influencing polar lipids, BAK (C12 and C14) can alter the details of molecular-level interactions between individual species of TFLL and indirectly influence the macroscopic behavior of the film, in particular its organization and stability.
A socioeconomic evaluation of early-stage and moderate glaucoma patients
Authors: Lindžiūtė Miglė , Janulevičienė Ingrida
Published: April 2021

Purpose: The aim of this study was to compare costs related to glaucoma treatment for early- and moderate-stage glaucoma patients.

Design: Descriptive observational study.

Methods: The study was conducted at the Eye Clinic in the Hospital of the Lithuanian University of Health Sciences Kauno Klinikos in Lithuania. An original questionnaire was administered to 80 open-angle glaucoma patients. Data regarding the age, gender, living area, occupation, income, concomitant diseases, frequency of outpatient visits, use of topical antiglaucoma and other medications, treatment and transportation costs were collected. The Hodapp classification was used to divide patients into two main groups of early- and moderate-stage glaucoma according to visual field loss. Results with p < 0.05 were interpreted as statically significant.

Results: There were 37 patients with early-stage glaucoma and 43 patients with moderate glaucoma. Moderate-stage glaucoma patients were 73 (± 8) years old, while patients with early-stage glaucoma were 63 (± 11) years old, (p < 0.001). Early-stage glaucoma patients visited their ophthalmologist 2.5 (± 1.5) times per year, while patients with moderate glaucoma had 4.4 (± 2.7) outpatient visits per year (p < 0.001). Patients with early-stage glaucoma used 1.8 (± 0.9) medications, while patients with moderate glaucoma used 2.9 (± 0.9) medications (p < 0.001). Combined costs for treatment and transportation totaled an average of 4.7% of patient income. Patients that were in the early stages of glaucoma spent about 3.2% of their annual income for glaucoma care and transportation, while patients with moderate-stage glaucoma spent about 5.9% of their income (p = 0.003).

Conclusion: Moderate-stage glaucoma patients had significantly higher expenses related to glaucoma than early-stage glaucoma patients. Costs related to glaucoma comprised a significantly greater part of the income of patients who were retired than patients who were employed.
On the recovery of the stress-free configuration of the human cornea
Authors: Pandolfi Anna , Montanino Andrea
Published: April 2021

Purpose: The geometries used to conduct numerical simulations of the biomechanics of the human cornea are reconstructed from images of the physiological configuration of the system, which is not in a stress-free state because of the interaction with the surrounding tissues. If the goal of the simulation is a realistic estimation of the mechanical engagement of the system, it is mandatory to obtain a stress-free configuration to which the external actions can be applied.

Methods: Starting from a unique physiological image, the search of the stress-free configuration must be based on methods of inverse analysis. Inverse analysis assumes the knowledge of one or more geometrical configurations and, chosen a material model, obtains the optimal values of the material parameters that provide the numerical configurations closest to the physiological images. Given the multiplicity of available material models, the solution is not unique.

Results: Three exemplary material models are used in this study to demonstrate that the obtained, non-unique, stress-free configuration is indeed strongly dependent on both material model and on material parameters.

Conclusion: The likeliness of recovering the actual stress-free configuration of the human cornea can be improved by using and comparing two or more imaged configurations of the same cornea.
STUDIES ON CULTURE IN SUSTAINABLE DEVELOPMENT IN THE MEKONG DELTA REGION OF VIET NAM FROM 1975 TO PRESENT ACHIEVEMENTS AND PROSPECTS
Authors: Pham Khanh Tiet
Published: April 2021

Using the research method of overview, this article presents an overview of studies on culture in the  sustainable development in the Mekong Delta region of Viet Nam from 1975 to present. Research results show that the works in Viet Nam from 1975 to present mainly emphasize on ecological, economic, political and social issues; however, the issue of culture in the Mekong Delta sustainable development has not been paid much attention to in-depth research, so there has not been a separate project to systematically assess the current situation of cultural impacts of the Mekong Delta, as well as ideas and solutions to improve the effectiveness of the positive impact of culture in sustainable development in the Mekong Delta region. On the basis of identifying the achieved achievements, the article proposes research prospects in terms of theory and practice of cultural issues in sustainable development in the Mekong Delta region.
Formação continuada dos formadores de professores da área de ciências da natureza
Authors: Radetzke Franciele Siqueira , Güllich Roque Ismael da Costa
Published: April 2021

O processo de formação continuada de professores no ensino superior é tomado como temática norteadora das discussões aqui apresentadas. Temos como intenção trazer resultados de uma pesquisa em que buscamos compreender os elementos constituintes de tal processo. Para dar conta das discussões, investimos na análise de narrativas produzidas por seis professores formadores que participam das ações de formação continuada desenvolvidas pelo projeto Ciclos Formativos em Ensino de Ciências. A produção de mônadas (ROSA; RAMOS, 2015), mediante textualização das narrativas, é a forma utilizada para tratar dos resultados. Entre os elementos que constituem o processo de formação continuada, destacaram-se: Diálogo Formativo; Sistematização de Experiências e Narrativas Reflexivas. O texto é um convite ao diálogo no tocante da Investigação-Formação-Ação como contexto que proporciona interlocuções sobre o ser, o estar e o fazer docente em ciências de forma crítica e reflexiva.
Optimasi Substitusi Saus Tomat dengan Ekstrak Buah Semu Jambu Monyet pada Formulasi Bumbu Marinasi Steak
Authors: Susanti Siti , Bintoro Valentinus Priyo , Hintono Antonius , Zuniati Neti , Arifan Fahmi
Published: April 2021

Ekstrak buah semu jambu monyet (EBSJM) sebagai bumbu marinasi menjadi salah satu aplikasi pemanfaatan jambu monyet di bidang pangan. Tujuan penelitian ini adalah menentukan level optimum EBSJM sebagai pensubstitusi saus tomat dalam formula bumbu marinasi ditinjau dari karakteristik fisikomikia dan hedoniknya. Empat level konsentrasi EBSJM dengan lima kali perulangan (0, 5, 10, dan 15%) dari proporsi saus tomat (v/v) ditetapkan dalam formula bumbu marinasi untuk menu steak. Produk bumbu steak untuk masing-masing formula selanjutnya dikarakterisasi fisikokimianya. Uji hedonik dilakukan dengan mengaplikasikan bumbu pada daging ayam yang diolah sebagai steak. Substitusi EBSJM pada saus tomat mempengaruhi karakteristik fisikokimia (viskositas, pH, kadar air, dan total padatan) bumbu marinasi dan karakteristik hedonik (rasa dan tekstur) pada steak sebagai hasil aplikasi dari bumbu tersebut. Viskositas dan total padatan makin meningkat sedangkan kadar air makin menurun pada substitusi lebih dari 5% (p<0,05). Penurunan pH bumbu makin bertambah seiring dengan penambahan substitusi hingga 10% (p<0,05). Uji hedonik menunjukkan substitusi 5% menghasilkan steak ayam yang paling disukai dari segi tekstur dan rasa (p<0,05). Substitusi saos tomat dengan EBSJM 5% menghasilkan produk bumbu marinasi untuk steak yang kental, asam, pekat dan paling disukai. Kata kunci : Ekstrak; bumbu; jambu monyet; marinasi Optimation on the Substitution of Tomato Sauce with Cashew Apple Extract in Formulation of Steak Marinade Seasoning ABSTRACTExtracts of cashew apple (EBSJM) as marinade seasoning is one of the applications of cashew apple utilization in the food sector. Study was aimed to determine the optimum level of EBSJM as a substitute for sauce in the marination seasoning formula reviewed from its physical and hedonic characteristics. Four levels of EBSJM concentration with five iterations (0, 5, 10, and 15%) of the sauce proportion (v/v) was defined in the marinade seasoning for steak. Steak seasoning products for each formula were further characterised by physicalochemistry. EBSJM substitution to tomato sauce affected the viscosity, pH, moisture content, and total solids of marinade seasoning and hedonic characteristics (taste and texture) in the steak as a result of the application of the seasoning. Viscosity and total solids increased while water levels decreased at substitutions by more than 5% (p<0.05). The decrease in seasoning pH increased in line with the addition of substitutions up to 10% (p<0.05). Hedonic tests showed a 5% substitution resulting in the most preferred chicken steak in terms of texture and taste (p<0.05). The substitution of tomato sauce with EBSJM 5% obtained the marinade products for steaks that were dense, sour, concentrated, and most preferred. Keywords: Cashew apple; extracts; margination;  seasonings
Fake Product Monitoring and Removal for Genuine Product Feedback
Authors: Patil Mayuri Manikrao , Nikumbh Snehal Nimba , Parigond Aparna Parshwanath
Published: April 2021

A customer’s decision to purchase a product or service are primarily influenced by online reviews. Customers use online reviews, which are valuable sources of information to understand the public opinion on products and/or services. Dependability on online reviews can give rise to the potential concern that violator could give deceitful reviews in order to synthetically promote or decry products and services. This practice is known as Opinion Spam, where spammers manipulate reviews by making fake, untruthful, or deceptive reviews to get profit and boost their products, and devalue a competitor’s products. In order to tackle this issue, we propose to build a fraud risk management system and removal model. This captures fraudulent transactions based on user behaviors and network, analyses them in real-time using Data Mining, and accurately predicts the suspicious users and transactions. In this system, we use two algorithms NLP and TF-IDF to differentiate between fake and genuine reviews or feedback received by the customers
Pattern Recognition using Support Vector Machines as a Solution for Non-Technical Losses in Electricity Distribution Industry
Authors: Aniedu Azubuike N. , Inyiama Hyacinth C. , Azubogu Augustine C. O. , Nwokoye Sandra C.
Published: April 2021

Contending with Non-Technical Losses (NTL) is a major problem for electricity utility companies. Hence providing a lasting solution to this menace motivates this and many more research work in the electricity sector in recent times. Non-technical losses are classed under losses incurred by the electricity utility companies in terms of energy used but not billed due to activities of users or malfunction of metering equipment. This paper therefore is aimed at proffering a solution to this problem by first detecting such loopholes via the analysis of consumers’ consumption pattern leveraging Machine learning (ML) techniques. Support vector machine classifier was chosen and used for classifying the customers’ energy consumption data, training the system and also for performing predictive analysis for the given dataset after a careful survey of a number of machine learning classifiers. A classification accuracy (and subsequently, class prediction) of 79.46% % was achieved using this technique. It has been shown, through this research work, that fraud detection in Electricity monitoring, and hence a solution to non-technical losses can be achieved using the right combinations of Machine Learning techniques in conjunction with AMI technology.
Aplikasi Penampil Informasi Data Tanaman Mangrove Menggunakan QR-Code di Hutan Mangrove Cilacap
Authors: Zakaria Andriansyah , Prihantara Andesita , Hartono Antonius Agung , Lystianingrum Rostika , Hazrina Fadhillah
Published: April 2021

EduWisata is a concept of developing an environmentally friendly tourism area by taking into accounts the resources and elements of education in a marine tourism package. The concept has been applied to the Cilacap mangrove forest area. The lack of information media in the mangrove forest area makes the visiting community still not get complete information about the types, classifications, benefits, and distribution of mangrove plants. Quick Response Code or also known as QR Code can be used as a media for storing information based on information technology in the form of a code image. The image of this code can be scanned using a QR code scanner. The QR Code system can also assist managers in improving the quality of service in the delivery of educational information on the types of mangrove plants found in mangrove forests to the public. The QR Code system is made using smartphone technology to scan QR codes. Mangrove plant data information will appear on the visitor's smartphone screen, so visitors will easily access information about mangrove plants.
Maintenance Costs and Advanced Maintenance Techniques: Survey and Analysis
Authors: Thomas Douglas S , Weiss Brian
Published: April 2021

The costs/benefits associated with investing in advanced maintenance techniques is not well understood. Using data collected from manufacturers, we estimate the national losses due to inadequate maintenance and make comparisons between those that rely on reactive maintenance, preventive maintenance, and predictive maintenance. The total annual costs/losses associated with maintenance is estimated to be on average $222.0 billion, as estimated using Monte Carlo analysis. Respondents were categorized into three groups and compared. The first group is the top 50 % of respondents that rely on reactive maintenance, measured in expenditures. The remaining respondents were split in half based on their reliance on predictive maintenance. The top 50 % of respondents in using reactive maintenance, measured in expenditures, compared to the other respondents suggests that there are substantial benefits of moving away from reactive maintenance toward preventive and/or predictive maintenance. The bottom 50 %, which relies more heavily on predictive and preventive maintenance, had 52.7 % less unplanned downtime and 78.5 % less defects. The comparison between the smaller two groups, which rely more heavily on preventive and predictive maintenance, shows that there is 18.5 % less unplanned downtime and 87.3 % less defects for those that rely more on predictive than preventive.
SUCCESSFUL NON SURGICAL MANAGEMENT OF A LARGE PERIAPICAL LESION – TWO CASE REPORTS
Authors: Kavimalar Kavimalar , Khatri Sonia , Mathew Sylvia , Shetty Nithin
Published: April 2021

Aim: The aim of these case reports is to emphasize the successful healing of large periapical lesions using non surgical endodontic treatment with
advanced techniques
Background: Periapical lesions of endodontic origin are common pathological conditions affecting the periradicular tissues. The primary
objective of root canal treatment is to cure or prevent periradicular periodontitis and to retain natural teeth in function and aesthetics
Case description: Two case reports of large periapical lesions are described here which have shown favourable clinical and radiographic outcome
following non surgical endodontic therapy
Conclusion: Size of a periapical lesion does not necessarily mandate surgical intervention always and has shown the potential to heal following
conservative endodontic therapy. Assessment of healing of a large periapical lesion necessitates a long term follow up and has to be done
periodically.
Clinical significance: The article highlights that present day endodontic treatment has become predictable and highly successful due to the
advancements in diagnostic imaging techniques, rotary instruments, irrigants , intracanal medicaments and obturation systems which has in turn
led to the fall in root end surgeries
EFFECT OF PHOTOTHERAPY ON SERUM CALCIUM LEVELS IN NEONATAL JAUNDICE
Authors: Gupta Aradhana , Bhardwaj Anand Kumar , Aggarwal Anisha , Chauhan Gauri
Published: April 2021

Background :To study the effect of phototherapy on serum calcium levels in neonates with unconjugated hyperbilirubinemia.
Methods : This hospital based longitudinal interventional study was conducted on 100 neonates with neonatal hyperbilirubinemia admitted to
Neonatal Intensive Care Unit at Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala. Total serum bilirubin
and serum calcium levels of each participants were checked before and at the end of phototherapy. Neonates were also checked for the clinical signs
of hypocalcemia i.e. jitteriness, irritability, lethargy, and convulsions.
Results : Atotal of 100 neonates with neonatal jaundice were included with 55% boys and 45 % girls whose mean age was 3.0 ± 0.95 days. Mean
S.Bilirubin level before phototherapy was 13.92 ± 2.32 mg/dl which was reduced to 8.87 ± 2.18 mg/dl. S.Calcium levels pre-phototherapy were
8.66 ± 0.65 mg/dl which were reduced to 7.94 ± 1.05 mg/dl. It was found that 32% of the participants in total exhibited symptoms related to
hypocalcemia. More term neonates (56.3%) experienced symptoms related to hypocalcemia compared to pre-terms (43.8%).
Conclusion : It can be deduced that phototherapy induced hypocalcemia is a signicant concern and hence, neonates requiring phototherapy may
be considered for calcium supplementation.
EFFECT OF PREOPERATIVE SUBLINGUAL MISOPROSTOL IN REDUCING INTRA AND POST-OPERATIVE BLOOD LOSS IN CESAREAN SECTION - A DOUBLE BLIND RANDOMIZED PLACEBO CONTROLLED TRIAL
Authors: Siria Begam Shermin , Ghosh Anuradha , Nurejjaman MD , jana Debarshi
Published: April 2021

INTRODUCTION: Postpartum hemorrhage and intra-operative blood loss during cesarean delivery is a major concern to all obstetrician.
Maternal mortality is unacceptably high worldwide. About 830 women die from pregnancy or child -birth related complications around the world
everyday. It was estimated that in 2015, roughly 303000 women died during and following pregnancy and child birth. PPH is the leading cause of
maternal mortality in low income countries, and the primary cause of nearly one quarter of all maternal deaths globally.
AIMS & OBJECTIVE:To measure the efcacy and safety of pre-operative sublingual misoprostol for decrease of blood loss during and after the
cesarean sections.
MATERIALS AND METHOD: There after subject recruitment was done form July 2018 to June 2019. Effect of sublingual misoprostol prior to
cesarean section just before skin incision to decrease bleeding during and after cesarean sections. Patients admitted for delivery in the Gynecology
& obstetrics department of SSKM Hospital.
RESULT AND ANALYSIS: Our study showed in Control Group, 4(4.3%) patients had needed Blood Trans fusion. Association of Blood Trans
fusion needed was statistically signicant (p=0.0431) between two groups. In SUB LINGUAL MISOPROSTOL Group, 7(7.6%) patients had
DIARRHOEA, 9(9.8%) patients had NAUSEA,8(8.7%) patients had SHIVERING,8(8.7%) patients had TEMPARATURE RISING and6(6.5%)
patients had VOMITING. Association of Adverse effects was statistically signicant (p<0.0001) between two groups. In Control group,
SUMMARY AND CONCLUSION: We found that Total blood loss (After delivery of baby and 24 hrs Post- op) was less in sub lingual
misoprostol groups compared to control group which was statistically signicant. Hard tone of Uterus during CS was higher in sub lingual
misoprostol group in compared to control group which was statistically signicant
ASSOCIATION OF ANKLE BRACHIAL INDEX WITH CARDIOVASCULAR AND SOCIODEMOGRAPHIC RISK FACTORS IN DIABETIC POPULATION
Authors: Bheda Sejal , Jiandani Mariya P , Mehta Amita
Published: April 2021

Lower-extremity arterial occlusive disease is much more likely to occur in patients with type II diabetes. Due to rapidly increasing prevalence of
Diabetes and its dreadful complications like amputation and associated mortality, it is crucial to screen symptomatic as well as asymptomatic
diabetic patients for peripheral arterial disease (PAD) at an early stage. There is immense evidence stating increased risk of coronary vascular
disease(CVD) and PAD in diabetics. The risk factors being similar to that of CVD, there is less information available regarding association of
Ankle brachial index with individual cardiovascular risk factors in diabetic population. This study was done with the objective to evaluate
association of Ankle Brachial Index (ABI) with Physical activity level, chronicity of Diabetes Mellitus ,cardiovascular risk factors and
sociodemographic factors.
Methods:Type 2 diabetic patients coming to diabetic-endocrinology OPD of tertiary care hospital were evaluated for Fasting Blood Sugar, Serum
Total cholesterol and Serum Triglycerides, International Physical Activity Questionnaire- long form (IPAQ LF). ABI was evaluated and interpreted
as per guidelines of American Heart Association. Data was analyzed using SPSS for windows version 16 software.
Results: Total 500 patients (male=271, female=229) with mean age 57.85 (± 9.66) years participated in the study. The association of ABI was
statistically signicant with Physical activity level (p= 0.005), chronicity of Diabetes Mellitus (p< 0.001), Glycemic control (p= 0.02), Serum Total
Cholesterol (p <0.001) and Serum Triglycerides (p = 0.032). The association of ABI with Waist circumference (p=0.307) and Smoking (p= 0.380)
was statistically not signicant. The study also revealed signicant association of ABI with age (<0.001), gender (<0.001), weekly sitting time (p=
0.002), presence of claudication symptom (0.019), annual family income (p= 0.021)and family history of diabetes mellitus (p= <0.001).
Conclusions: This study revealed signicant association of Ankle Brachial Index with cardiovascular risk factors and socio-demographic
parameters.
EVALUATION OF SERUM URIC ACID AND ITS CORRELATION IN YOUNG NEWLY DIAGNOSED ESSENTIAL HYPERTENSIVES
Authors: Narayan Atindra , Sharma Kuber , Sharma D.K.
Published: April 2021

Background: Hypertension is a major public health challenge and is the third leading killer in the World. The serum uric acid has shown some
prognostic importance in essential hypertension
Methodology: Acase control study was undertaken in a tertiary care hospital in Gurugram. Seventy ve cases of hypertension and equal number of
controls were studied for the hypertension and serum uric acid levels.
Results:This study had shown that, majority of the cases and controls were aged 31 – 40 years and females. The blood pressures were signicantly
more in the cases than controls. Serum uric acid levels were also signicantly higher in cases than controls. There was no statistically signicant
difference in serum uric acid levels between different stages of hypertension.
Conclusion:The serum uric acid levels were signicantly higher in cases of hypertension than controls.
AN ABDOMINAL INFECTION SIMULATING MALIGNANCY : A CASE REPORT
Authors: Konyala Varsha , M Poornima
Published: April 2021

Tuberculosis is notorious for its afiction to the lungs.However, one mustn't forget the case burden that extra pulmonary TB imposes.Here we
present a case of a middle aged woman who came with non specic complaints per abdomen.Her abdominal pain, discomfort, loss of weight and
appetite along with clinical examination and investigations pointed towards malignancy. On surgical exploration and histopathological
examination, the case was conrmed as that of abdominal TB.Tuberculosis of the abdomen is one of the extra pulmonary sites where tubercular
bacilli can reside. In such cases, apart from treating tuberculosis medically with anti tubercular therapy, one must also order a chest X-ray to identify
any pulmonary foci of tuberculosis. This is to curb any potential spread of infection. Further, one must look acutely at cases with non specic
ndings and consider TB in the differential diagnosis, particularly if the patient hails from a TB endemic region.With a keen eye for tuberculosis
along with corroborative and relevant investigations, one can diagnose this chronic illness and put patients well on the road to recovery.
Configuraciones sobre el sentido del juego para el pueblo ancestral Misak del resguardo Guambia
Authors: Isaza Gómez Germán Darío , Córdoba Rentería Libardo , Bedoya Taborda Ana María
Published: April 2021

Colombia es un país pluricultural, multiétnico, aún la habitan alrededor de 103 Pueblos Indígenas; además, se conservan 65 lenguas propias de las comunidades nativas. El objetivo del estudio fue comprender el sentido del juego para la comunidad Indígena Misak del resguardo la Marquesa, ubicada en el departamento del Cauca. El estudio siguió la lógica de la investigación acción, la cual se orientó desde la lógica introspectivo vivencial, donde se utilizó la observación etnográfica participante y no participante, entrevistas a profundidad como instrumentos importantes para condensar los elementos significativos y recurrentes que suceden alrededor del juego. Comprender los diversos juegos como el Tsarap Lulepik, Chanchiku, Tsik Pala Nepuna Ampik, Lasrúarúk y el Dchama, constituyen una forma cultural de comprender sus luchas por su pervivencia ancestral, sino una conexión con su pensamiento de sus mayores desde el Isup; generando una convivencia con la naturaleza, la vida y su territorio a través del Aship; conectando las vivencias de los ancestros, quienes viven a plenitud desde el Merep; las cuales se relacionan con las diversas actividades de la vida cotidiana de la comunidad desde el Marep.
Aprendiendo educación económica y financiera como habilidad básica en la sociedad moderna en enseñanza remota
Authors: Valbuena-Duarte Sonia , Heras Rambal Mónica del Amparo
Published: April 2021

El presente artículo socializa una investigación cuyo objetivo busca fomentar una competencia básica necesaria en la sociedad moderna, como lo es la educación económica y financiera, promoviendo además la argumentación y la resolución de problemas en temas de economía y finanzas con niños de ocho años de edad en promedio. La investigación con un enfoque cualitativo y diseño de investigación acción, se recolectó información a través de observación participante, cuestionarios y análisis de datos aplicados a niños de tercer grado de escolaridad perteneciente a una institución de carácter oficial de un municipio del norte colombiano. A partir de los análisis realizados se diseña e implementa una estrategia basada en un recurso tecnológico de uso libre. Los resultados revelan que los estudiantes se enfrentan y resuelven los problemas relativos con la educación económica y financiera de forma más segura y organizada y con mejores resultados cuando desarrollan una estrategia de resolución, lo cual impacta también su nivel argumentativo mostrando evolución y mayor apropiación de contenidos en relación con la educación   económica  y  financiera. Al ponderar los niveles argumentativos se logran mayor desarrollo en competencias para comprender, decidir de manera razonada y responsable, administrar eficientemente los recursos y planear las metas a corto y largo plazo. Concluyendo que la educación económica y financiera puede empezarse a temprana edad en las instituciones educativas obteniéndose resultados favorables para la formación de ese futuro ciudadano de la sociedad moderna.
Escala cuantitativa para medición del grado de infección en semillas de arroz a nivel de laboratorio
Authors: Méndez-Molina B L , Moreno-Rozo L Y , Vergel-Ortega M
Published: April 2021

En la investigación se reactivaron los aislados bacterianos en medio líquido JMV para evaluar la virulencia de Burkholderia glumae frente a semillas de arroz certificadas por Fedearroz variedades F67, F68 y F2000; se procedieron a desinfectar las semillas, consecutivamente se dejaron en agua destilada estéril por 2 días; luego se secaron y se ajustó el DO del inóculo de Burkholderia glumae (aislados Bg007, Bg010 y Bg011), realizando diluciones para evaluar concentraciones desde 108 hasta 103 células por mililitro; se procedió a agitar las semillas con el inóculo, llevadas posteriormente vacío durante 10 minutos por cada dilución llevándose a cajas de Petri con papel filtro humedecido con agua destilada estéril durante 7 días; crecidas las plántulas se procedieron a medir parámetros y nivel de severidad. Se procedió a hacer el análisis estadístico mediante Software es IBM SPSS Statistics, el cual permitió obtener Gráficas De Dispersión, Diagramas De Barras De Error; Comparaciones Multivariante, la Prueba de Muestras Relacionadas se realizó a partir Comparación de las Medias. Se hizo conteo de frecuencias, junto con sus Diagramas de Frecuencias, se dividió las medidas en quintiles para realizar una escala cuantitativa de severidad. El análisis estadístico permitió evidenciar que la cepa más virulenta fue el aislado Bg007 y la menos virulenta el aislado Bg011, la variedad de arroz más afectada fue la F2000 y la menos afectada fue la F68.
Una vivencia escolar para la construcción de ciudadanía, derecho al buen trato ya la integridad personal
Authors: Muñoz Muñoz Cristian Fernan
Published: April 2021

La presente investigación tiene como objetivo identificar las situaciones cotidianas que son percibidas por los estudiantes del grado primero como vulneradoras de los Derechos Humanos (DH) de una Institución Educativa Pública, facilitandosu restitución através de una propuesta didáctica. Para tal fin, el problema es abordado desde la teórica educativa para la ciudadanía y la democraciadonde se resalta la importancia de la formación ciudadana para la transformación del actuar en sociedad.El diseño metodológico se fundamenta en la investigación acción educativa con procesos de reflexión acción reflexión, hasta construir un caso semireal, donde se prioriza las situacionesque percibe el grupo. Se abordó desde la observación participante y la producción de los estudiantes. Como resultado se identificó el derecho a la integridad y el buentrato como los más vulnerados.A partir de este derecho se elaboró una propuesta didáctica para promover sureconocimiento y restitución, a través de la estrategia pedagógica de estudio decaso, en las áreas de ciencias sociales y competenciasciudadanas.Los principales agentesvulneradores son las familias, los compañeros en la escuela y vecindario y en algunos casos auto vulneración.El mayor logro con el trabajo didáctico es el autorreconocimiento de los niños como sujetos de derechos, y las expresiones cotidianas deconvivencia   como el autorespeto, el respeto a la diferencia, la valoración de símismos y de los demás.