bluuebunny/crossref_metadata_2025 huggingface dataset:
Wstęp do metodologii badań nad mniejszością składniową na przykładzie współczesnego polskiego reportażu książkowego
Authors: Ostrowska Katarzyna Małgorzata
Published: December 2022

Przedmiotem opisu tego szkicu jest płaszczyzna językowa współczesnego polskiego reportażu książkowego, którego ramy wyznaczane są poprzez ograniczenia czasowe (współczesność, XXI wiek), językowe (język polski), a także formy (książka). Podstawowym celem niniejszego artykułu jest prezentacja metodologii badań nad mniejszością składniową wraz z egzemplifikacją konstrukcji syntaktycznych, których frekwencja wynosi poniżej 10%, na podstawie wypowiedzeń z korpusu tekstów należących do gatunku współczesnego polskiego reportażu książkowego. Metodologia wykorzystywana w badaniach nad mniejszością składniową obejmuje dwie podstawowe metody: (1) analizę składniową oraz (2) analizę kwantytatywną. Pierwsza z wymienionych wiąże się z doborem odpowiedniego modelu składniowego. Druga zaś wiąże się z analizą kwantytatywną. W ten sposób w tym artykule dokonano analizy 200 wypowiedzeń z każdego reportażu, uzyskując tym samym ogólną liczbę 2000 zbadanych konstrukcji składniowych. Po dogłębnej analizie zwrócono uwagę na te elementy syntaktyczne charakterystyczne dla stylu gatunku reportażu książkowego, które pokrywają mniej niż 10% spośród wszystkich konstrukcji składniowych lub spośród określonego typu konstrukcji.
Ismail Kadare’s literary strategies
Authors: Kobayashi Hisako
Published: December 2022

The Albanian writer Ismail Kadare (b. 1936) is sometimes called “a great writer in a small country”; this paper, focusing on his historical novel The Three-Arched Bridge (1978), reveals some strategies inherent to his works, suggests their place in world literature, and asserts how they can be seen as both unique and universal as part of world literature. First, the paper examines how legends have been reconstructed in the novel and compares them to two similar works. Second, the paper analyzes how architecture functions in the novel. Third, a parallel universe or “an-other Albania” is described so as to show how Kadare’s literary universe is formed.
The Use of Coprostanol, Epi-Coprostanol and Cholesterol in Evaluating Potential Sewage Input from Downstream River towards Marine Environment
Authors: Abdul Zali Munirah
Published: December 2022

Contamination of sewage is a major concern in the river and marine environments since sewage can cause disease and ecosystem health problems. Worldwide, coprostanol, coprostanol and epi-coprostanol were used in sewage assessment due to their resistance towards environmental stressor. This study assessed the distribution of coprostanol, epi-coprostanol and cholesterol in the particulate of sewage treatment plant (STP) effluents and river water samples. The targeted analytes were extracted using sonication and quantified using gas chromatography-mass spectrometer (GC-MS). The potential sewage pollution in the river and marine environments were assessed using diagnostic approach and linear regression technique. Based on the result, cholesterol (mean = 15.6 mg L-1) was found to be higher than coprostanol (mean = 6.0 mg L-1) and epi coprostanol (mean= 2.3 mg L-1) in STPs samples. Similar to STPs, cholesterol (mean= 4.6 mg L-1) also was detected higher than coprostanol (mean= 2.4 mg L-1) and epi-coprostanol (mean= 2.4 mg L-1) in the river water samples. The double plot ratios of epi-coprostanol/cholesterol versus epi-coprostanol/coprostanol revealed the discharge of treated and untreated sewage into the river water. The river water samples were impacted by treated sewage and non-human sources. The linear regression analysis indicates potential moderate to high increasing trend (p<0.05) of sewage discharge towards downstream of the river. These findings provide an enhanced means in assessing sewage contamination input into the river and its potential effect towards the marine ecosystem.
KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIK DENGAN DIALISIS DI ASIA TENGGARA : A SYSTEMATIC REVIEW
Authors: Anggraini Sevrima , Fadila Zurayya
Published: December 2022

Gagal ginjal kronik (GGK) merupakan masalah kesehatan dunia. Pasien yang mengalami gagal ginjal biasanya akan melakukan terapi penggantian ginjal yang akan memiliki efek terhadap kualitas hidup pasien. Beberapa studi menunjukkan bahwa pasien gagal ginjal kronik yang menjalani dialisis akan mengalami penurunan kualitas hidup. Oleh karena itu penting untuk mengetahui faktor apa saja yang mempengaruhi kualitas hidup pasien gagal ginjal kronik yang menjalani dialisis. Peneliti melakukan telaah sistematis terhadap kualitas hidup pasien gagal ginjal yang menjalani dialisis. Peneliti melakukan penelusuran terhadap beberapa database yaitu ProQuest, PubMed dan Science direct dan telaah terhadap beberapa studi yang sesuai dengan kriteria inklusi dan eklusi. Berdasarkan hasil telaah sistematis diketahui bahwa status sociodemografi seperti umur, pendidikan, status pekerjaan dan etnis berhubungan dengan kualitas hidup pasien gagal ginjal. Selain itu status klinis dan gangguan psikologis juga berhubungan dengan kualitas hidup pasien. Jenis terapi dialisis juga berhubungan dengan kualitas hidup dimana beberapa studi menemukan bahwa pasien yang menjalani terapi dialisis dengan dialisis peritoneal memiliki kualitas hidup yang lebih baik dibandingkan pasien yang menjalani terapi hemodialisis. Kesimpulan dari penelitian ini adalah terdapat beberapa faktor yang mempengaruhi kualitas hidup pasien GGK yaitu faktor sosiodemorafi, status klinis dan gangguan psikologis serta jenis terapi dialis yang digunakan. 
Pendugaan Kemunduran Benih dengan Uji Fisiologi dan Biokimiawi
Authors: Jawak Gani , Widajati Eny , Liana Devi , Astuti Tri
Published: December 2022

Pengujian viabilitas benih merupakan salah satu uji rutin yang dilakukan dalam proses sertifikasi benih. Penurunan viabilitas benih dapat dilakukan secara biokimiawi dan secara fisiologi. Penelitian ini dilakukan dengan maksud untuk mempelajari kemunduran benih melalui pengujian secara biokimiawi dan secara fisiologi. Penelitian menggunakan dua lot benih kacang panjang (lot tinggi dan lot rendah). Uji viabilitas benih secara fisiologi dilakukan melalui uji daya berkecambah dan secara biokimiawi melalui uji respirasi dengan teknik pewarnaan menggunakan tetrazolium (TTZ) dan metode titrasi. Percobaan dirancang menggunakan rancangan acak lengkap satu faktor. Data yang diperoleh dianalisis dengan uji F dan korelasi Pearson. Hasil penelitian menunjukkan bahwa perlakuan lot benih beberbeda nyata terhadap tolok ukur uji tetrazolium dan berat kering kecambah total sedangkan untuk tolok ukur indeks vigor, daya berkecambah, dan respirasi tidak menunjukkan perbedaan yang nyata. Terdapat korelasi yang positif tinggi pada tingkat respirasi benih lot tinggi dan benih lot benih rendah terhadap tolok ukur berat kering kecambah total, daya berkecambah, indeks vigor, dan uji tetrazolim. Oleh karena itu, uji biokimiawi dengan TTZ dan respirasi dengan metode titrasi dapat dijadikan alternatif untuk menduga kemunduran benih dengan cepat.
İMAR PLANINDA UMUMİ HİZMETE1 AYRILAN TAŞINMAZIN TAHSİSİNE “ÖZEL” İFADESİNİN EKLENMESİNE DAİR BİR ÖZEL HUKUK İNCELEMESİ
Authors: BAKIRCI Münevver Kübra
Published: December 2022

Bu çalışmada, imar planında umumi hizmete ayrılan özel hukuka tabi taşınmazın tahsisine “özel” ifadesinin
eklenmesinin mülkiyet hakkı üzerindeki etkisi değerlendirilmektedir. Uygulamada, ilgili idareler tarafından
taşınmazın umumi hizmete tahsisini öngören imar planında değişiklik yapılarak taşınmazın tahsisine “özel” ifadesi
eklenmektedir. Bu çerçevede mesela eğitim alanına ayrılmış taşınmaz, özel eğitim alanına tahsis edilmekte ve
taşınmazda özel kullanıma imkân tanınması sebebiyle sınırlandırmanın ölçülü olduğu iddia edilmektedir. Çalışmada
öncelikle idareler tarafından geliştirilen bu uygulamanın içeriği ve hukuki dayanağı ele alınmakta ve konu hakkında
Danıştay ve Anayasa Mahkemesi’nin kararlarına yer verilmektedir. Ardından imar planında umumi hizmete ayrılmış
taşınmaz üzerinde özel tesis yapma imkânı veren İmar Kanunu’nun 13. maddesinin 2. fıkrasının içeriği
incelenmektedir. Nihai olarak da imar planı değişikliği ile taşınmazda özel kullanıma imkân tanınması uygulaması,
İmar Kanunu m. 13/2 çerçevesinde ele alınarak özel mülkiyete konu taşınmaz üzerindeki etkisi açısından
değerlendirilmektedir.
Blasting Quarry Operations: Land Use Compatibility Issues and Potential Property Value Impacts
Authors: Sevelka Tony
Published: December 2022

Aggregate resources are essential for road and building construction. In 2019, the US domestic production reached 1.53 billion tons of crushed stone valued at $18.7 billion produced by an estimated 1,430 companies operating 3,440 quarries, according to the U.S. Geological Survey (USGS) Mineral Commodity Summaries. But, it is also recognized that a quarry blasting below the water table is one of the most noxious, toxic and destructive uses of land, with no reasonable prospect of post-extraction-rehabilitation. If permitted and established in the wrong geographic location, a blasting quarry operation can result in significant deleterious impacts on the environment and local inhabitants and can disrupt short and long-term land use planning objectives. Because a quarry can remain operational for 100+ years, impacting five or more generations; quarries have the potential to cause permanent environmental degradation, destabilize communities, damage, sterilize or diminish the use and enjoyment of residential and non-residential properties, and reduce property values. Blasting is the preferred method of extracting rock in a quarry operation, the consequences of which can lead to environmental and property damage, and to injury or death of human and non-human life. In North America, licensing and operational oversight of a pit or quarry are primarily controlled by the individual states, territories and provinces, and address matters of compliance, while issues related to land use planning and zoning are entirely within the jurisdiction of the local municipalities, counties or regions. Accordingly, this research paper seeks to inform land use planners of the importance of protecting the environment and its inhabitants from the adverse effects, including the diminution in property values, associated with aggregate extraction operations generally and blasting quarries specifically, through the use of permanent onsite setbacks and offsite separation distances to avoid land use incompatibility and sensitive land uses.
DESTILASI AIR TANAH SEBAGAI SALAH SATU UPAYA UNTUK MENINGKATKAN KUALITAS AIR DI DESA PENYAK KABUPATEN BANGKA TENGAH
Authors: Rolan Rolan , Roehafi Firza , Ambarwati Julia , Prayuda Muhammad , Junaidi Junaidi , Yusron Yusron , Latupapua Flourenchia Charolline , Agustika Dwi Roblia , Indriawati Anisa
Published: December 2022

Air bersih merupakan salah satu kebutuhan pokok yang dibutuhkan bagi manusia dalam kehidupan secara berkelanjutan. Penggunaan air bersih sangat berkaitan erat dalam kehidupan sehari-hari seperti konsumsi rumah tangga, kebutuhan industri, dan tempat umum yang memang memerlukan air bersih dalam penggunaannya. Himpunan Mahasiswa Fisika dalam kegiatan Bina desa melaksanakan pembuatan destilator air dengan melibatkan warga. Pembuatan alat ini memiliki tujuan untuk bisa mengatasi permasalahan air sumur yang ada tetapi belum dimanfaatkan dengan baik sebagai sumber air bersih karena kondisi air yang keruh dan berbau menyengat. Kegiatan ini mendapatkan respon yang baik dari msyarakat karena hasil air yang didestilasi sangat jernih.

Kata kunci : Bina Desa, Air, Alat Destilasi, Sosialisasi
Pemanfaatan Satwa Liar sebagai Obat Tradisional di Desa Terak dan Teru, Kabupaten Bangka Tengah
Authors: Syafutra Randi , Fitriana Fifin , Kamal Abdul , Wulandari Fika , Wulan Nur Azizah Nawang , Alamsyah Zikri
Published: December 2022

Terak and Teru Villages are two of the eleven villages surrounding Gunung Mangkol Grand Forest. Since a long time ago, the people in these villages have fulfilled their daily needs by utilizing the natural resources around Gunung Mangkol Grand Forest. One of the natural resources in the grand forest is wild animals commonly used as traditional medicine. This research was undertaken to find out what wild animals are used as traditional medicine by the people of Terak and Teru Villages; and to find out what parts are used, types of utilization, and processing methods of the wild animals. The research was conducted from November 1, 2021 to November 29, 2021. The research methods used were collecting data by surveys and selecting respondents using the snowball sampling technique. Selected respondents were then interviewed according to the questionnaire. Based on the research results, nine species of wild animals were used as traditional medicine by the people of Terak and Teru Villages. The parts of wild animals used were bile, liver, meat, and whole bodies. The types of use of wild animals were male stamina enhancer, asthma medicine, skin pain medicine, surgical wound medicine, malaria medicine, typhus medicine, cough medicine, toothache medicine, burn treatment, and headache medicine. The methods of processing wild animals were unprocessed, dried in the sun for the oil, roasted / burnt, and fried.
ASSESSMENT OF SWEET CHERRY CULTIVARS OBTAINED AT RESEARCH STATION FOR FRUIT GROWING IASI, ROMANIA
Authors:   Research Station for Fruit Growing Iași, Romania, Iurea Elena , Sîrbu Sorina ,   Research Station for Fruit Grwoing Iași, Romania, Corneanu Margareta ,   Research Station for Fruit Grwoing Iași, Romania, Golache Iuliana Elena ,   Research Station for Fruit Grwoing Iași, Romania, Mineață Iulia ,   Research Station for Fruit Grwoing Iași, Romania, Ungureanu Ionuț Vasile ,   Research Station for Fruit Grwoing Iași, Romania
Published: December 2022

The aim of this paper is to present valuable features of sweet cherry cultivars with different maturation ages of the fruits approved at RSFG Iasi between 2017 to 2021. Due to its fruits ripening age being earlier than other fruit-growing species (beginning with May), the cherry represents the first link in the annual chain of fruits production. Analysing the bloom phenophase, it was noticed that the cultivars Margonia and Croma bloom period was about two weeks later than the other cultivars. The maturation age of the fruits was spread over 57 days, starting on May the 21st for cultivar 'Cătălina', ending on July 16th for cultivar 'George'. Statistically, in terms of fruits weight (g) and equatorial diameter (mm), cultivars 'Alexus' (9.4 g and 26.6 mm), 'Elaiaşi' (8.8 g and 25.4 mm), 'Croma' (8.0 g and 24.2 mm), 'Maria' (7.8 g and 23.7 mm) and 'Tereza' (7.8 g and 25.4 mm) were highlighted with superior significant differences in comparison with the control cultivar 'Van' (7.4 g and 25.2 mm). In terms of the fruits content in soluble dry substance, cultivars 'Tereza' (19.2%), 'Alexus' (18.6%), 'Maria' (17.8%) and 'Cătălina' (17.8%) recorded superior significant values in comparison with the control cultivar 'Van' (17.7%). All the studied cultivars presented superior resistance to the fruits cracking phenomenon in comparison with the control cultivar 'Van' (41.8%) recording values below 16%.
IMPROVING THE ASSORTMENT WITH NEW PEAR VARIETIES, OBTAINED AT RSFG VOINEȘTI
Authors:   Research Station for Fruit Growing Voinești, Romania, Erculescu Mihaiela , Andreieș Nistor ,   Research Station for Fruit Growing Voinești, Romania
Published: December 2022

The pear (Pyrus communis) breeding at the Research Station for Fruit Growing (RSFG) Voinesti, Romania began in 1950, but since 1960 it has been introduced as the main selection objective, resistance to the main diseases and pests along with other agrobiological and technological characteristics. The main source of resistance to disease and pests is some cultivated biotypes with genetic ancestry in Pyrus serotina. Over a period of more than half a century, a vast biological material was selected, which served to register, between 2004 and 2021, 7 pear varieties: 'Corina' (2004), 'Orizont' (2004), 'Tudor' (2007), 'Romcor' (2009), 'Cristal' (2009), 'Aroma' and 'Andrei' (2021), who cumulated in their genotype the most qualities established for selection. There are also many perspective selections in the test cultures field trial.
STUDY OF GENETIC DIVERSITY IN PLUM GENOTYPES USING SRAP MARKERS
Authors:   National Agricultural Research-Development Institute, Fundulea, Romania., Ciucă Matilda , Butac Mădălina ,   Research Institute for Fruit Growing Pitesti, Romania, Conțescu Elena Laura ,   National Agricultural Research-Development Institute, Fundulea, Romania., Turcu Alina Gabriela ,   National Agricultural Research-Development Institute, Fundulea, Romania., Iordăchescu Mihaela ,   University of Agronomic Sciences and Veterinary Medicine of Bucharest, Romania
Published: December 2022

The hexaploid European plums (Prunus domestica L. and Prunus domestica subsp. insititia (L.) C.K.Schneid.) are main traditional fruit tree culture in Romania and represent an economically important fruit species with limited information on its genetic structure. Our objective was to fingerprint 33 cultivars using four Sequence-Related Amplified Polymorphism (SRAP) primer pairs to estimate the genetic relationships among local and international cultivars. The primer pairs amplified a total of 70 alleles ranging from 14 to 21 alleles per marker. A wide range of fragment length was detected among the accessions, from 65 to 2000 bp. The mean number of alleles per primer combination was 17.5, with the most alleles obtained with SRAP80 (21 alleles), range between 65-1800 bp and the fewest alleles (14) were obtained with SRAP95, range between 150-2000 bp. The neighbor-joining dendrogram, based on Rogers genetic distance, of the plum germplasm studied, consisted of two main clusters of different sizes: 23 entries were grouped into cluster 1 and the remaining 10 entries were grouped into cluster 2. It is interesting that cultivars representing plum species with 6x and 2x ploidy levels were clustered together. Another interesting aspect observed refers to plum genotypes clustered closely on the dendrogram according to their pedigree, such as 'Dani' (P14) - 'Tita' (P15), 'Roman' (P7) - 'Early Rivers' (P9), 'Zamfira' (P6) - 'Pescăruș' (P33). Accessions within the Romanian landrace/old autochthonous cultivars group were not clustered together. Regarding the PCA, the first two principal axes accounted for 12.91% (CP1) and 10.46% (CP2) of the total variation, respectively, together explaining 23.37% of the total variability. Our results showed that SRAP markers represent valuable tools for genetic diversity study on Prunus domestica. To our knowledge, this is the first study using SRAP markers for characterization of P. domestica germplasm. In the future, this molecular genetic information can be combined with phenological and biochemical data to identify genes, quantitative trait loci (QTL) and molecular markers that can be used to improve the plum crop breeding program.
ANTIOXIDANT ACTIVITY AND PHENOLIC PROFILE OF FRUITS FROM SOME ROMANIAN SHRUB FRUIT VARIETIES
Authors:   „Cantacuzino” National Military Medical Institute for Research and Development, Bucharest, Romania, Popa Claudia Valentina ,   University of Bucharest, Bucharest, Romania, Avramescu S ,   University of Bucharest, Bucharest, Romania, Oprea Eliza ,   University of Bucharest, Bucharest, Romania, Nicola Claudia ,   Research Institute for Fruit Growing Pitesti, Romania, Paraschiv Mihaela ,   Research Institute for Fruit Growing Pitesti, Romania, Hertzog Radu ,   „Cantacuzino” National Military Medical Institute for Research and Development, Bucharest, Romania, Coman Mihail ,   Research Institute for Fruit Growing Pitesti, Romania
Published: December 2022

The berries are rich in polyphenols, vitamins, and other bioactive compounds, and exhibit antioxidant, antimicrobial, anti-inflammatory and anticancer activities. In this work, antioxidant activity (AA) and a phenolic profile of berries fruits belonging to the Aronia melanocarpa (Michx.) Elliott, ʹMelromʹ cv., Lonicera caerulea var. kamtschatica, ʹKamiʹ cv., and Sambucus nigra L., ʹElromʹ cv. were studied. All three cvs. were previously patented by the Research Institute for Fruit Growing Pitesti, Romania. Alcoholic extracts from berries were obtained by four methods: continuous, maceration, ultrasounds and microwaves-assisted. The antioxidant content of extracts was evaluated by an HPLC method. AA was determined by DPPH free radical scavenging method. Total phenol, flavonoid, and anthocyanin contents were determined by spectrophotometric methods. The AA values were reported as equivalents (µg mL-1 extract) caffeic and gallic acids, morin, quercetin, rutin, and are in concordance with the results of the chromatographic method. In addition, the chromatographic method allowed identifying the p-coumaric acid, caffeic acid, chlorogenic acid, rutin, and epicatechin. The experimental results have shown that analyzed fruit extracts have high antioxidant activity, due mainly to flavonoids and anthocyanins in high concentration. Therefore, extracts from mentioned berries can be used in different nutraceutical products with high antioxidant potential.
IMPACT OF ACIDIFICATION ON ALUMINUM IN THE SOILS OF HIGHBUSH BLUEBERRY PLANTATIONS FERTILIZED WITH COMPOST OBTAINED FROM URBAN SLUDGE
Authors:   Research Institute for Fruit Growing Pitesi, Romania, Nicola Claudia , Paraschiv Mihaela ,   Research Institute for Fruit Growing Pitesi, Romania
Published: December 2022

Different fertilization systems cause changes in the content of mobile forms of Al (aluminum) in the soil, due to changes in pH. The toxicity Al is one of the major limitations that inhibits the growth and development of plants in acidic soils. In acidic soils (pH <5.0), phytotoxic aluminum (Al3+) rapidly inhibits root growth and subsequently affects the absorption of water and nutrients by plants. Stationary fertilization experiments with wastewater sludge compost treatments to blueberry plants were evaluated. In the spring of 2020, an experiment with increasing doses of compost of 0, 20, 40, 60, 80 t /ha in vegetation pots, under soil water controlled conditions, was organized. Three years after compost fertilization, a 4.2 pH level (strong acid) was experimentally induced in the soil of all vegetation vessels planted with blueberries. The content of phytotoxic forms of aluminum increased with increasing dose of compost, compared to unfertilized control. At the induction of the soil pH of 4.2, in the variant fertilized with the maximum dose of compost (80 t/ha) the mobile and phytotoxic content of Al increased 30 times compared to the same experimental variant from the pre-acidification conditions. In the same time, under the newly created conditions, the mobile phosphorus content in the soil decreased dramatically. In the compost maximum fertilization dose, the mobile phosphorus content from the soil was significantly lower than the unfertilized control.
Effect of E-Filling Application and Knowledge of Taxation on Taxpayer Compliance at Tax Service Office
Authors: Mawarni Agnes , Jamali Hisnol , Mispa Sitti
Published: December 2022

The Effect of E-Filing Application and Knowledge of taxation on Taxpayer Compliance at  Tax Service Office (KPP) (Cuonselling by Hisnol Jamali and Sitti Mispa). This research purpose to determine the effect of the e-filing application and knowledge of taxation on taxpayer compliance at North Makassar KPP Pratama. The data used is primary data from respondents who are distributed through questionnaires to taxpayers at KPP Pratama North Makassar with a random sampling technique. The population is 174,000 registered taxpayers at the North Makassar Pratama Tax Service Office, while the sample taken is 96 taxpayers. The method of data collection is descriptive analysis of multiple linear regression analysis, testing the validity and reliability of the data, testing the classical assumptions and testing the hypotheses
Association Between Benzodiazepines and Dementia in South Korea: A Nation-Wide Study
Authors: Sun Tai hui , Yeom Ji Won , Cho Chul-Hyun , Lee Heon-Jeong
Published: December 2022

Objective: Benzodiazepines are a widely used class of medications for anxiety, depression, and insomnia. Despite their common use, concerns remain about memory problems with benzodiazepines. Despite the growing financial and social burden of dementia, inconsistent results persist regarding the association between benzodiazepines and dementia. Therefore, we aimed to evaluate the association between benzodiazepines and dementia in Korea. Methods: Diagnostic and prescription information from the Health Insurance Review and Assessment (HIRA) database in South Korea between 2009 and 2014 was utilized. The dementia group included people who were diagnosed with a dementia code and received one or more prescriptions for dementia. A total of 68,241 participants with dementia and 341,205 control participants were matched. Possible confounders, such as major medical and psychiatric disorders, were adjusted, and multivariate logistic regression was conducted to assess the association between benzodiazepines and dementia. Results: The highest odds ratio (OR) for dementia was noted for clonazepam (OR=2.86, 95% confidence interval [CI]=2.77–2.95) followed by those for diazepam (OR=2.60, 95% CI=2.53–2.66), lorazepam (OR=1.34, 95% CI=1.30–1.37), and triazolam (OR=1.26, 95% CI=1.21–1.32). Conclusion: Overall, relatively long-acting benzodiazepines, such as clonazepam, diazepam, and lorazepam, were associated with the incidence of dementia. Triazolam, which is approved for insomnia, was also significantly associated with dementia. Individuals who are prescribed with benzodiazepines should be cautious regarding memory loss and dementia. Further studies are needed to confirm the temporal and biological causality between benzodiazepines and dementia.
Claims for Space: Unpacking Finnish Geohistorical Imaginations of the United States
Authors: Skurnik Johanna
Published: December 2022

This chapter explores how geographical texts and maps represents the historical roots of Finns in America and made them visible on the map of the United States, in essence to map a Finnish history in settler colonial North America and to carve Finns a place on the continent. The chapter shows how Finnish geohistorical imaginations have developed through an enagement with the settler colonial artographic frame as Finnish presence entangled with questions of colonial violence and land ownership in multifaceted ways.
Life Writing as a Settler Colonial Tool: Finnish Migrant-Settlers Claiming Place and Belonging
Authors: Saramo Samira
Published: December 2022

By writing their stories of settlement in Canada and the United States over the decades, Finnish migrants and their descendants have claimed their place and belonging in these national histories. Through autobiographical and family history life writing, migrant-settler authors contribute personal narratives of migration, adversity, adventure, and (most often) positive integration that collectively build a rich view of Finnish lives and communities in North America. Through these texts, we are able to see some of the strategies and practices Finns have employed in establishing their North American migrant settlerhood.
Türkiye’nin Cari Açık Dinamiklerinde Enerji Açığının Rolü ve Finansman Kalitesi
Authors: EROĞLU İlhan , BURSAL Mücella
Published: December 2022

Son yıllarda Türkiye’nin en önemli sorunları arasında cari açık sorunu yer almaktadır. Makroekonomik istikrarın tesis edildiği sürdürülebilir bir büyümenin gerçekleşmesi için Türkiye’nin sürdürülebilir bir cari açık düzeyinin yakalanması gerekmektedir. Bu çalışmada Türkiye’nin cari açık dinamikleri ve cari açık içinde önemli bir payı olan enerji açığının önemi ve finansmanı kalitesi konu edilmiştir. Çalışmada cari açığın kontrolünde enerji açığının kontrolünün önemli olduğu, enerji açığı ile mücadelede takip edilmesi gereken politika setinin Türkiye’nin zayıf ve güçlü yönleri dikkate alınarak oluşturulması gerekliliğine dikkat çekilmiştir.
A novel next-generation sequencing capture-based strategy to report somatic hypermutation status using genomic regions downstream to immunoglobulin rearrangements
Authors: McCafferty Neil , Stewart James Peter , Darzentas Nikos , Gazdova Jana , Catherwood Mark , Stamatopoulos Kostas , Langerak Anton W. , Gonzalez David
Published: December 2022

The somatic hypermutation (SHM) status of the clonotypic, rearranged immunoglobulin heavy variable (IGHV) gene is an established prognostic and predictive marker in chronic lymphocytic leukemia (CLL). Analysis of SHM is generally performed by polymerase chain reaction (PCR)-amplification of clonal IGHV-IGHD-IGHJ gene rearrangements followed by sequencing to identify IGHV gene sequences and germline identity. Targeted-hybridization next-generation sequencing (NGS) can simultaneously assess clonality and other genetic aberrations. However, it has limitations for SHM analysis due to sequence similarity between different IGHV genes and mutations introduced by SHM, which can affect alignment efficiency and accuracy. We developed a novel SHM assessment strategy using a targeted-hybridization NGS approach (EuroClonality- NDC assay) and applied it to 331 samples of lymphoproliferative disorder (LPD). Our strategy focuses on analyzing the sequence downstream to the clonotypic, rearranged IGHJ gene up to the IGHM enhancer (IGHJ-E) which provides more accurate alignment. Overall, 84/95 (88.4%) CLL cases with conventional SHM data showed concordant SHM status, increasing to 91.6% when excluding borderline cases. Additionally, IGHJ-E mutation analysis in a wide range of pre- and post-germinal center LPD showed significant correlation with differentiation and lineage status, suggesting that IGHJ-E analysis is a promising surrogate marker enabling SHM to be reported using NGS-capture strategies and whole genome sequencing.
Influence of Organizational Factors on the Formation of Mental Maladaptation in Medical Workers during the Pandemic of a New Coronavirus Infection Covid-19
Authors:   Bashkir State Medical University, Ufa, Russian Federation, Matuzov G.L. , Masyagutova L.M. ,   Bashkir State Medical University, Ufa, Russian Federation,   Ufa Research Institute of Occupational Health and Human Ecology, Ufa, Russian Federation
Published: December 2022

Summary. The aim of the study is to analyze the modern foreign and domestic scientific literature devoted to the influence of production factors on the formation of mental maladaptation in medical workers, as well as possible methods of its prevention and curing. Materials and research methods. Scientific studies of negative psychological reactions and manifestations of mental disorders in medical workers of various profiles in the COVID-19 pandemic were analyzed. The search protocol included the use of various databases, including PubMed; Russian information and analytical portal in science, technology, medicine, and education — eLIBRARY.ru; open-access statistical reporting data; and official websites of scientific journals on the subjects under study. Study results and their analysis. The results of the study showed that most medical professionals experienced stress caused by organizational factors such as a lack of personal protective equipment (PPE), fears of not being able to receive quality medical care if they were sent to work elsewhere, fears of rapidly changing context, lack of access to current information and communication, lack of special medications, shortage of ventilators and beds in intensive care units In the conditions of regular health care work, most of the professionals noted tension in the process of performing professional duties, exceeding their physical and mental capacities, which was one of the main reasons for anxiety, nervousness or stress at work.
Organization of Training in the Basics of Tactical Medicine with Citizens of the Orenburg Region Called Up for Military Service as Part of Partial Mobilization
Authors:   Orenburg State Medical University of the Ministry of Health of Russian Federation, Orenburg, Russian Federation, Kuzmin S.A. , Grigorieva L.K. ,   Orenburg State Medical University of the Ministry of Health of Russian Federation, Orenburg, Russian Federation
Published: December 2022

Summary. The aim of the study is to analyze practical training in the basics of tactical medicine with citizens called up for military service in the framework of partial mobilization. Materials and research methods. In the course of practical classes on the basics of tactical medicine were used: individual medical kits — AIM-3S, cloak tents, sanitary straps, improvised means. The exercises included training in: methods of applying a tourniquet for external bleeding; ways of immobilizing limbs if they are injured; performing anti-shock measures; applying bandages on a wound and the order of evacuation of wounded to a safe area. All practical exercises were conducted in the field conditions. Study results and their analysis. Classes with citizens called up for military service as part of partial mobilization were conducted on the training range of the training center responsible for manning the military unit of territorial defense. The servicemen learned necessary skills of first aid in self- and mutual aid modes in the red, yellow and green danger zones. Various methods of evacuating wounded to a safe zone were practiced. The training program was executed completely, learning goal was achieved.
Peculiarities of Modern Local Wars and Armed Conflicts and Problems of Medical Care in Prehospital Period
Authors:   Moscow Territorial Scientific and Practical Center for Disaster Medicine (TSEMP) of the Moscow City Health Department, Moscow, Russian Federation, Pisarenko L.V. , Gumenyuk S.A. ,   Moscow Territorial Scientific and Practical Center for Disaster Medicine (TSEMP) of the Moscow City Health Department, Moscow, Russian Federation, Potapov V.I. ,   Moscow Territorial Scientific and Practical Center for Disaster Medicine (TSEMP) of the Moscow City Health Department, Moscow, Russian Federation
Published: December 2022

Summary. The aim of the study is to investigate the peculiarities of modern local wars and armed conflicts, their influence on the structure of sanitary and non-return losses among population on the basis of scientific publications analysis. It also aims to define the principal problems of organization and rendering medical aid to wounded, sick and injured under these conditions and to outline the possible ways of their solution. Materials and research methods Materials of research — domestic and foreign publications, which analyze modern local wars and armed conflicts and assess their striking effect on vital functions and vitality of population. Method of research — review-analytical. Results of the study and their analysis. The features of modern local wars and armed conflicts, their impact on the structure of combat and non-combat losses among the population are highlighted. The inefficiency of the present system of medical and evacuation measures for urgent and emergency medical indications in the prehospital period was presented, especially in the conditions of combat operations. There were defined both advantages and problems of wide and effective application of capabilities, forces and means of the Disaster Medicine Service and ambulance service for rendering first and medical (emergency and urgent) aid to the population in regions of military actions and in extreme situations. A variant has been suggested to combine forces and means of medical service of civil defense, ambulance and emergency medical service into a united universal branch system called “operative-tactical medicine” aimed at optimization and increase of effectiveness of medical aid rendering to population in prehospital period both in conditions of everyday activity and in extreme conditions of modern local wars, armed conflicts and other emergency situations.
Exogenous Application Of Potassium Silicate For Growth Enhancement And Salt Stress Alleviation In Coriander (Coriandrum Sativum L.)
Authors: Kapoor Riti Thapar , Yadav Arti
Published: December 2022

Salinity is a major threat to agriculture and its adverse effect on farming land is expanding day by day. In the present study effects of potassium silicate on germination and biochemical parameters of Coriandrum sativum under salt stress were studied. The maximum seed germination (94%) of coriander seeds was observed with potassium silicate. Total chlorophyll content showed the following order: PS > C > NaCl (2mM) + PS > NaCl (4 mM) +PS > NaCl (6mM) +PS > NaCl. Potassium silicate enhanced biochemical components such as sugar, proline, protein and total antioxidant contents in coriander seedlings. The maximum total antioxidant content (46%) was observed in NaCl (6mM) + PS treatment. Hence, potassium silicate acts as a growth stimulating agent and can be used as fertilizer for coriander plants under salt stress.
Bangladesh J. Bot. 51(4): 669-675, 2022 (December)
Effect of different organic manures on production of Lepidium sativum under Morus based agroforestry system
Authors: Gautam Krishan Lal , Bishist Rohit , Thakur Chaman Lal , Gautam Kamini , Sharma Harish , Sharma Archana
Published: December 2022

Agroforestry is a sustainable land use system that integrates trees and shrubs on farmlands and rural landscapes to enhance productivity, profitability, diversity and ecosystem sustainability. In the present study effect of different organic manures on production of Lepidium sativum (a veterinary galactogogue/medicinal herb) under open conditions and Morus alba based agroforestry system was investigated. The experiment comprised of 8 treatments. It was observed that treatment T7 recorded higher plant height whereas other growth and yield parameter were recorded to be maximum in treatment T6. Highest number of branches, number of main stem, number of pods, yield parameters were observed in treatment T6 while the lowest was recorded in treatment T4. From the economical point of view, the treatment T3 resulted in higher net return (1154.27 USD $ ha-1) and BC ratio (2.44).
Bangladesh J. Bot. 51(4): 797-805, 2022 (December)
Association of Carotid Artery Intima Media Thickness With Ischemic Stroke Patients
Authors: Uddin Md Jasim , Rahman Aminur , Islam Md Rafiqul , Sabuj Md Shahidullah , Mamun Abdullah Al , Roy Niloy Ranjan
Published: December 2022

Background: Atherosclerotic risk factors frequently lead to ischemic stroke. The thickness of the carotid intima-media thickness (CIMT) is a significant indicator for early atherosclerosis alterations. The aim of the study is to evaluate the association between ischemic stroke patients and CIMT.
Methods: A total of 50 patients were recruited in this cross-sectional descriptive study which was carried out in the Department of Neurology, BSMMU, from January 2015 to June 2016. All patients of ischemic stroke were confirmed by history, examination and CT scan of head/MRI of brain. Carotid ultrasound scan was done to detect intima-media thickness (IMT) of both sided carotid bifurcation, common carotid and internal carotid artery and performed by a single sonographer at the Department of Neurology, BSMMU.
Results: This population has a total of 27 male and 23 female with mean age 60.7± 13.6 years. Maximum patients (72%) were found to be above 50 year of age. After risk factor stratification among the study population, HTN, dyslipidemia was the most followed by positive family history, smoker, DM, IHD. Among study population 45 cases were anterior circulation stroke and only 5 cases were posterior circulation stroke. Maximum mean IMT=1.2± 0.3, minimum mean IMT=1.0±0.10 mm and least IMT was 0.7mm. (Normal CIMT value is < 0.8mm). The mean IMT was higher at symptomatic side in comparison to the asymptomatic side. Higher IMT was found mostly at the carotid bifurcation and higher IMT at one site was significantly correlated with other sites (r= +0.435, p=0.002), there was also correlation between IMT and risk factor (r=+0.265, p=0.063). Increased IMT was more marked in patients with risk factors in comparison to without risk factor, like smoker & nonsmoker but not statistically significant (ORR=2.00, 95% CI 0.636- 6.286, p=0.233).
Conclusion: The present Study found that extra-cranial carotid artery intima media thickness (IMT) was higher than normal level in ischemic stroke patients. Higher CIMT was found at symptomatic side in comparison to the asymptomatic side.
Bangladesh J Medicine 2022; 33: 24-30
THE RELATIONSHIP BETWEEN APOB AND APOA1 WITH INSULINEMIC STATUS IN PREDIABETIC SUBJECTS
Authors: Mazumdar Reaz Mohammad , Hoque Mohammad Razuanul , Mohajan Suman , Khan Imran , Hassan Md Zahid , Faruque Md Omar , Ali Liaquat , Kabir Md Golam
Published: December 2022

The present study was mainly aimed at exploring the causal association of the atherogenic (ApoB) and antiatherogenic apolipoproteins (ApoA1) and their ratio in the basic defects of pancreatic β cell dysfunction and insulin resistance in type 2 Diabetes Mellitus (T2DM). An intermediate stage towards diabetes, the prediabetic stage, was chosen to explore the association. Following a standardized selection process, 131 subjects were purposefully recruited for the study, including 18 with impaired fasting glucose (IFG), 56 with impaired glucose tolerance (IGT), and 57 with type 2 diabetes (T2DM). Fifty-nine healthy subjects served as controls. Glucose, lipid and insulin were estimated by glucose-oxidase, enzymatic colorimetric assay and enzyme linked immunosorbent assay (ELISA) respectively. Serum ApoB and ApoA1 were estimated by immuno-nephelometric method. Appropriate statistical tools were used to calculate statistical differences using Statistical Package for Social studies (SPSS) for Windows V12. Absolute insulin (mIU) levels were significantly higher in the IGT and T2DM groups compared to controls (p 0.001 and p = 0.001, respectively). HOMA%B (meanSD) was significantly lower in T2DM groups (p=<0.001) and higher in IGT compared to the controls although it is significantly lower in IFG compared to the controls but mean value is about 90%. HOMA%S was significantly lower in IGT and T2DM group (p=0.001 and 0.002 respectively). ApoA1 levels were significantly higher only in the T2DM group (p = 0.027), whereas ApoB levels were higher in both the IGT and T2DM groups (p = 0.026-0.001).. Neither ApoB nor ApoA1 showed any significant difference in the IFG group as compared to control. ApoB-ApoA1 ratio did not show significant difference among the groups. ApoB showed significant positive correlation with both fasting and postprandial glucose (p=0.006 and 0.040 respectively). In IGT group ApoB was positively correlated with absolute insulin (p=0.025) and HOMA%B (p=0.049) and negatively with HOMA%S (p=0.026). ApoB, but not ApoA1 or the ApoB and ApoA1 ratio, seem to have a causal association with insulin resistance, and elevation of ApoB is also modulated by obesity and atherogenic lipids.
Bioresearch Commu. 9(1): 1170-1176, 2023 (January)
HEAVY METAL CONTENT IN BEEF COLLECTED FROM LOCAL MARKETS OF DHAKA AND ASSESSING THE HEALTH RISK
Authors: Akanda Rubel , Quraishi Shamshad B , Mamun Sumaiya
Published: December 2022

Around the world, beef is consumed as a healthy source of protein, fat, niacin, vitamins B6, B12, iron, zinc, and phosphorus. There is mounting evidence that beef is becoming increasingly contaminated with heavy metals, particularly lead (Pb) and chromium (Cr). The purpose of this study was to determine the amounts of the lead (Pb) and chromium (Cr) in beef. Five large markets in Dhaka city—Mirpur-1, New Market, Karwan Bazar, Kaptan Bazar, and town hall market of Mohammadpur—were chosen to gather samples of beef. In this study, the Pb and Cr content in beef was estimated by the Zeeman method using graphite furnace atomic absorption spectrophotometer (GFAAS). The microwave digester finished the digestion of beef. The Pb and Cr content in beef were estimated in mg/kg. Total lead (Pb) content in a beef sample of Mirpur -1, New Market, Karwan Bazar, Kaptan Bazar and Mohammadpur was found to be 0.563±0.084, 0.845±0.127, 0.159±0.024, 0.063±0.009 and 0.143±0.021 mg/kg respectively (Minimum detection limit is 0.06 mg/kg). On the other hand, total chromium (Cr) content in beef sample from Mirpur -1 was found below the detection limit of the method (Minimum detection limit is 0.05 mg/kg). The Cr content in beef from New market, Karwan Bazar, Kaptan bazaar and Mohammadpur was found to be 0.05±0.007, 0.052±0.008, 0.121±0.018 and 0.053±0.008 mg/kg respectively. According to Codex Alimentarium Commission (CAC), the acceptable limit of lead content in beef is 0.1 mg/kg and there is no standard for chromium set by international organization like WHO/FAO, CAC. Brazil has set 0.1 mg/kg as permissible chromium content in beef (Ihedioha et al., 2014). Except for Kaptan Bazar, the chromium content was found to be within Brazil's permissible limit. Surprisingly, only Kaptan Bazar had acceptable lead content that was within the CAC limit.
Bioresearch Commu. 9(1): 1196-1202, 2023 (January)
GENOMIC ANALYSIS TO ELUCIDATE THE ANTIBIOTIC RESISTANCE MECHANISM OF EXTREMELY DRUG-RESISTANT PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM BANGLADESH
Authors: Zahra Fatimah Az , Jabeen Ishrat , Uddin Mohammed Jafar , Nahar Nazmun , Islam Sohidul , Shuvo Sabbir R
Published: December 2022

Multidrug-resistant P. aeruginosa has potential to cause nosocomial infections. In this study, whole-genome sequencing was performed of two extremely drug-resistant novel strains SRS1 and SRS4 isolated from Bangladesh. The size of draft genome of SRS1 is 6.8 Mbp, and 7.0 Mbp for SRS4. In silico analysis predicted that the genome of SRS1 has 82 and SRS4 has 75 antibiotic-resistant genes (ARGs). Antibiogram results revealed that both SRS1 and SRS4 were resistant to multiple members of the antibiotic groups of β−lactam, quinolones, and aminoglycosides families. In addition, the genomes of both SRS1 and SRS4 were predicted to have multiple mobile elements like prophages and plasmids. Comparative genome analysis with wildtype PAO1 and another drug-resistant P. aeruginosa strain JNQH-PA57 revealed that SRS1 and SRS4 contain more antibiotic resistance genes like AAC (6´)-II, ANT (2´´)-Ia, ANT (3´´)-IIa, OXA-395, PME-1, qacEΔ1, tet(A), tet(D), VEB-9 than PAO1 and JNQH-PA57. This study shows the importance of the genomic study to understand the distribution of ARGs in Bangladeshi P. aeruginosa strains to demonstrate the mechanisms responsible for multi drug resistance.
Bioresearch Commu. 9(1): 1208-1214, 2023 (January)
Dye Decolorization and Organic Compounds Removal of Synthetic Textile Effluent (STE) by Anaerobic-aerobic Magnetic Activated Sludge (A2-MAS) Reactor
Authors: Saha Mihir Lal , Oda Masato , Sakai Yasuzo
Published: December 2022

The developed anaerobic-aerobic magnetic activated sludge (A2-MAS) reactor was found to be suitable for the textile effluent management. An azo dye (Orange II) and an anthraquinone dye (Remazol brilliant blue R) were used in the synthetic effluent (STE) for dye decolorization. The A2-MAS reactor consisted of an anaerobic tank (8.0 L) sequenced with an aerobic tank (4.0 L) for simultaneous dye decolorization and organic compounds removal. The anaerobic tank was operated at 35 ± 1°C while the aerobic part was maintained at room temperature. The magnetic separation technique in both aerobic and anaerobic condition of A2-MAS reactor was found effective and it is completely new to anaerobic operation. The sequential A2-MAS reactor attained well with 99.6% dye decolorization and 90.7% CODCr removal with the initial loading of 34.2 mg/l dye compounds and 365 mg/l CODCr, respectively. Anaerobic treatment played the major role for both dye decolorization (96.8%) and CODCr removal (78.4%) for the period of 100 day. Interestingly, sludge emission was zero all throughout the treatment.
Plant Tissue Cult. & Biotech. 32(2): 115-125, 2022 (December)