bluuebunny/crossref_metadata_2025 huggingface dataset:
Noninvasive Assessment of Internal and External Player Load: Implications for Optimizing Athletic Performance
Authors: Heishman Aaron D. , Curtis Michael A. , Saliba Ethan , Hornett Robert J. , Malin Steven K. , Weltman Arthur L.
Published: January 2018

Heishman, AD, Curtis, MA, Saliba, E, Hornett, RJ, Malin, SK, and Weltman, AL. Noninvasive assessment of internal and external player load: implications for optimizing athletic performance. J Strength Cond Res 32(5): 1280–1287, 2018—Few data exist that assess athlete tracking and monitoring for the development of strategies to optimize performance and reduce fatigue in elite athletes. The purpose of the present study was to assess the efficacy of external load and internal stress monitoring as assessment tools for examining a performance index of fatigue. A retrospective analysis was performed on data collected over the course of the preseason in 10 elite male NCAA Division 1 basketball players. Internal stress was assessed using Omegawave Technology readiness scores and compared with the performance index of countermovement jump (CMJ). The external load that accumulated during the previous practice, quantified by PlayerLoad (PL; Catapult), was compared with CMJ values and Omegawave scores. The results indicated that high, compared to low CNS Omegawave Readiness Scores (6.7 ± 05.1, 4.5 ± 1.2 AU; p < 0.001), were associated with increased CMJ (62.1 ± 6.5 vs. 59.4 ± 6.6 cm; p = 0.05), Power (6,590 ± 526.7 vs. 6,383.5 ± 606.8 W; p = 0.05), Omegawave Overall Readiness (5.8 ± 1.1 vs. 5.0 ± 0.7 AU; p = 0.05), and Omega Potential (Omega) (21.3 ± 6.3 vs. 9.9 ± 20.8 mV; p = 0.07). An increased PL during the previous exposure was associated with decreased CMJ (58.7 ± 4.7 cm vs. 60.4 ± 5.1 cm; p < 0.001) and increased TRIMP (135.1 ± 35.9 vs. 65.6 ± 20.0 AU; p < 0.001), and duration (115.4 ± 27.1 vs. 65.56 ± 20.0 minutes; p = < 0.001) despite no differences in Omegawave CNS Readiness scores. We conclude that Omegawave and Catapult technologies provide independent information related to performance and may be effective tools for monitoring athlete performance.
Four-Week Unstructured Break Improved Athletic Performance in Collegiate Rugby Players
Authors: Jensen Courtney D. , Gleason Derrick , VanNess Mark
Published: January 2018

Jensen, CD, Gleason, D, and VanNess, JM. Four-week unstructured break improved athletic performance in collegiate rugby players. J Strength Cond Res 32(6): 1671–1677, 2018—This study analyzed the changes in athletic performance and anthropometric characteristics in collegiate male club rugby athletes (n = 14) after a 4-week winter break. All measurements were collected before and after the break. Body composition was assessed by body mass index and hydrostatic weighing. Performance measurements were as follows: V̇o
2max, vertical jump, 10-yard sprint, squat max, and bench press max. Before testing, each subject was acclimated to the protocols to reduce learning effects. During the 4-week break, no workouts were provided for the athletes; it was unsupervised and unstructured. Participants were required to maintain and submit self-reported nutritional and activity logs during this period. After the break, the athletes demonstrated a 5.0% improvement in V̇o
2max (absolute increase of 2.25 ml·kg−1·min−1), 6.8% improvement in vertical jump (1.50 inches), and a 14.3% increase in squat max (38.64 lb). Although increases in body mass (1.0%) were not significant, the body fat percentage exhibited a relative increase of 19.3% (absolute change from 13.35 to 15.93%). A significant discriminate function analysis indicated statistical differences between groups based on these variables. Self-reported behavior logs confirmed participation in >3 days of moderate to intense physical activity per week but somewhat poor dietary habits. These results indicate that collegiate rugby athletes may not need prescribed exercise routines during seasonal breaks in the athletic schedule. However, it may be beneficial to provide structured nutritional advice during unsupervised periods.
Post Activation Potentiation and Concentric Contraction Performance: Effects on Rate of Torque Development, Neuromuscular Efficiency, and Tensile Properties
Authors: Gago Paulo , Zoellner Anja , Cézar Lima da Silva Julio , Ekblom Maria M.
Published: January 2018

Gago, P, Zoellner, A, Cezar, J, and Ekblom, MM. Post activation potentiation and concentric contraction performance: effects on rate of torque development, neuromuscular efficiency and tensile properties. J Strength Cond Res 34(6): 1600–1608, 2020—This study investigated how a 6-second maximal voluntary isometric contraction (MVIC) conditioning affected plantar flexor twitch rate of torque development (RTDTW), as well as peak torque (PTCC) and rate of torque development (RTDCC) of maximal voluntary concentric contractions (MVCC) performed at 60°·s−1. RTDCC and normalized triceps surae electromyography signals (EMGTS) were measured during different phases of contraction. In addition, muscle tendon unit passive stiffness index (SI) calculated from the torque-angle relation was measured after each MVCC. Enhancements were found in the RTDTW immediately (by 59.7%) and up to 480 seconds (by 6.0%) after MVIC (p < 0.05). RTDCC during the 100–200 ms, 50–200 ms, and 0–200 ms phases and PTCC were enhanced (by 5.7–9.5%) from 90 to 300 seconds after conditioning (p < 0.05). Neuromuscular efficiency increased (decreased EMGTS/RTDCC) in the 50–200 ms and 0–200 ms phases by 8.8–12.4%, from 90 to 480 seconds after MVIC (p < 0.05). No significant changes were found in the SI or in RTDCC during the 50–100 ms phase, suggesting that the enhancements reported reflect mainly contractile rather than neural or tensile mechanisms. PAP effects on PTCC and RTDCC were significant and more durable at a lower velocity than previously reported. Enhancement in RTDCC and neuromuscular efficiency were found to be more prominent in later phases (>100 ms) of the MVCC. This suggests that enhanced contractile properties, attained through MVIC, benefit concentric contraction performance.
Leptin and Leptin Receptor Genes Are Associated With Obesity-Related Traits Changes in Response to Aerobic Training Program
Authors: Leońska-Duniec Agata , Jastrzębski Zbigniew , Jażdżewska Aleksandra , Krzysztof Ficek , Cięszczyk Paweł
Published: January 2018

Leońska-Duniec, A, Jastrzębski, Z, Jażdżewska, A, Krzysztof, F, and Cięszczyk, P. Leptin and leptin receptor genes are associated with obesity-related traits changes in response to aerobic training program. J Strength Cond Res 32(4): 1036–1044, 2018—Leptin (LEP) and leptin receptor (LEPR) genes have been studied for their potential association with development of human obesity and its related complications. Therefore, we have decided to check whether selected body mass, body composition, and metabolic variables observed in physically active participants will be modulated by the polymorphisms. The genotype distribution was examined in a group of 201 women measured for chosen traits before and after the completion of a 12-week aerobic training program. Our results revealed a significant interaction between training and LEP genotype for glucose level. A training-related decrease in plasma glucose concentration in the LEP AG heterozygotes differed significantly from the change in the homozygotes. The polymorphism was also associated with fat-free mass (FFM), total body water (TBW), total cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) levels. Another finding was a significant interaction between training and LEPR for LDL-C level. As opposed to AG and GG, AA homozygotes demonstrated a training-related decrease in LDL-C level. Our findings also showed that the LEPR G allele is connected with obesity-related traits. The participants with the GG genotype had higher body mass, body mass index (BMI), FFM, and TBW during the entire study period. This study provides evidence that polymorphisms in the LEP and LEPR genes are associated with the magnitude of the effects of regular physical activity on glucose and LDL-C levels, respectively. In addition, we found the association of the G allele of the LEPR polymorphism with body mass and BMI.
Influence of Femoral Acetabular Impingement on Squat Performance
Authors: Kolber Morey J. , Feldstein Amanda P. , Masaracchio Michael , Liu Xinliang , Hanney William J.
Published: January 2018

THE SQUAT IS A FUNDAMENTAL MOVEMENT FOR WEIGHTLIFTING AND SPORT PERFORMANCE AND MAY BE USED FOR ASSESSING INJURY RISK AND FUNCTIONAL INDEPENDENCE. THE PURPOSE OF THIS COLUMN IS TO PRESENT AN EVIDENCE-BASED DISCUSSION OF THE INFLUENCE THAT FEMORAL ACETABULAR IMPINGEMENT MAY HAVE ON SQUAT PERFORMANCE.
Prepubertal Development of GABAergic Transmission to Gonadotropin-Releasing Hormone (GnRH) Neurons and Postsynaptic Response Are Altered by Prenatal Androgenization
Authors: Berg Tova , Silveira Marina A. , Moenter Suzanne M.
Published: January 2018

Gonadotropin-releasing hormone (GnRH) neurons regulate reproduction through pulsatile GnRH release. Women with polycystic ovary syndrome (PCOS) have persistently elevated luteinizing hormone release frequency, reflecting GnRH release; this exacerbates hyperandrogenemia and disrupted reproductive cycles that are characteristic of this disorder. Clinical evidence suggests that neuroendocrine features of PCOS may manifest peripubertally. Adult mice prenatally exposed to androgens (PNA) mimic several reproductive features of PCOS. GnRH neurons from these mice have increased firing activity and receive increased GABAergic transmission, which is excitatory. When changes emerge during development is unknown. To study the typical postnatal development of GABAergic transmission and the effects of PNA treatment and sex, whole-cell voltage-clamp recordings were made of GABAergic postsynaptic currents (PSCs) in GnRH neurons in brain slices from prepubertal through adult control and PNA female and male mice. GABAergic transmission was present by 1 week of age in females and males and increased in frequency, reaching adult levels at 3 and 4 weeks, respectively. GABAergic PSC frequency was elevated in 3-week-old PNA versus control females. PSC frequency in both controls and PNA mice was activity independent, suggesting that PNA induces changes in synapse organization. PNA also alters the functional response of GnRH neurons to GABA. GABA induced firing in fewer neurons from 3-week-old PNA than control females; membrane potential depolarization induced by GABA was also reduced in cells from PNA mice at this age. PNA thus induces changes during development in the presynaptic organization of the GABAergic network afferent to GnRH neurons as well as the postsynaptic GnRH neuron response, both of which may contribute to adult reproductive dysfunction.

SIGNIFICANCE STATEMENTThe central neuronal network that regulates reproduction is overactive in polycystic ovary syndrome (PCOS), a leading cause of infertility. Recent evidence of neuroendocrine dysfunction in midpubertal girls suggests that the pathophysiological mechanisms underlying PCOS may arise before pubertal maturation. Prenatal exposure to androgens (PNA) in mice mimics several neuroendocrine features of PCOS. GABAergic transmission to gonadotropin-releasing hormone (GnRH) neurons is important for reproduction and is increased in adult PNA mice. The typical development of this network and when changes with PNA and sex arise relative to puberty are unknown. These studies provide evidence that PNA alters prepubertal development of the GABAergic network afferent to GnRH neurons, including both the presynaptic organization and postsynaptic response. These changes may contribute to reproductive dysfunction in adults.
A Conceptual Review of Lab-Based Aggression Paradigms
Authors: McCarthy Randy J. , Elson Malte
Published: January 2018

Aggression is often defined as a behavior that is done with the intent to harm an individual who is believed to want avoid being harmed (e.g., Baron & Richardson, 1994). Accordingly, social scientists have developed several tasks to study aggression in laboratory settings; tasks that we refer to as “lab-based aggression paradigms.” However, because of the legal, ethical, and practical issues inherent in provoking aggression within the confines of a laboratory setting, it is feasible to study only very mildly harmful aggression. The current conceptual review examines the criteria that are necessary to study aggression in a laboratory setting, discusses the strengths and weaknesses of several new and/or commonly-used lab-based aggression paradigms, and offers recommendations for the future of lab-based aggression research. Collectively, we hope the current discussion helps researchers to describe the contributions and limitations of lab-based aggression research and, ultimately, helps to improve the informativeness of lab-based aggression research.
Projected sea surface temperatures over the 21st century: Changes in the mean, variability and extremes for large marine ecosystem regions of Northern Oceans
Authors: Alexander Michael A. , Scott James D. , Friedland Kevin D. , Mills Katherine E. , Nye Janet A. , Pershing Andrew J. , Thomas Andrew C.
Published: January 2018

Global climate models were used to assess changes in the mean, variability and extreme sea surface temperatures (SSTs) in northern oceans with a focus on large marine ecosystems (LMEs) adjacent to North America, Europe, and the Arctic Ocean. Results were obtained from 26 models in the Community Model Intercomparison Project Phase 5 (CMIP5) archive and 30 simulations from the National Center for Atmospheric Research Large Ensemble Community Project (CESM-LENS). All of the simulations used the observed greenhouse gas concentrations for 1976–2005 and the RCP8.5 “business as usual” scenario for greenhouse gases through the remainder of the 21st century. In general, differences between models are substantially larger than among the simulations in the CESM-LENS, indicating that the SST changes are more strongly affected by model formulation than internal climate variability. The annual SST trends over 1976–2099 in the 18 LMEs examined here are all positive ranging from 0.05 to 0.5°C decade–1. SST changes by the end of the 21st century are primarily due to a positive shift in the mean with only modest changes in the variability in most LMEs, resulting in a substantial increase in warm extremes and decrease in cold extremes. The shift in the mean is so large that in many regions SSTs during 2070–2099 will always be warmer than the warmest year during 1976–2005. The SST trends are generally stronger in summer than in winter, as greenhouse gas heating is integrated over a much shallower climatological mixed layer depth in summer than in winter, which amplifies the seasonal cycle of SST over the 21st century. In the Arctic, the mean SST and its variability increases substantially during summer, when it is ice free, but not during winter when a thin layer of ice reforms and SSTs remain near the freezing point.
Critical Qualitative Inquiry
Authors: Koro-Ljungberg Mirka , Cannella Gaile S.
Published: January 2018

This introduction to the special issue does not only introduce the content of the issue, it also generates connections among histories, traditions, theories, thinkers, thoughts, actions, and power. We propose that critical qualitative inquiry that would further expand theoretically informed, engaged activism is of greater importance than ever as we experience unprecedented technological change, violence against living beings that are not labeled human (through experimentation, industrialization, and medicine), the plundering of the Earth, and increasing gaps between the privileged and the marginalized (whether rich/poor, human/nonhuman). Critical qualitative inquiry must be continuously rethought, repurposed, reinvigorated, and envisioned as always already leading to a justice-oriented action.
Becoming Cyborg
Authors: Huckaby M. Francyne
Published: January 2018

This article explores the chimeric hybridity of portable camera, sound recorder, filmmaker, and audience as research and activist cyborg weaving. Situating filmmaking in critical qualitative, ethnographic, and sociological traditions, I share my journey into becoming woman and machine—cine-eye-ear—in the struggle for continued access to public education. Throughout this article I use lowercase letters to deemphasize the importance of the individualized human in cyborg connection.
Thinking Critically with Children of the Anthropocene
Authors: Somerville Margaret
Published: January 2018

In her Deleuzean analysis of advanced capitalism, Braidotti notes that all previous emancipatory positions have been co-opted by the marketplace and that even our earth others – animals, seeds, plants, and the Earth as a whole – have been subsumed by advanced capitalism. This article addresses the need for a reconceptualised critical qualitative inquiry within the context of advanced capitalism and increasing recognition of human-induced changes in the planet's biosphere. Justice is understood in relation to the more-than-human world and its entangled children born into the 21st century. Stenger's recommendation of thinking with the more-than-human is adapted to thinking methodologically with children in an experiment designed to explore intra-action. The article concludes that following children in their playful encounters opens a space where matter and meaning, time and space, and the being of the adult researcher is reshaped into an entangled material world.
Affirmative Critique as Minor Qualitative Critical Inquiry
Authors: Andersen Camilla Eline
Published: January 2018

This article considers what to do with a political questioning of how to perform qualitative research when engaging with stuck bodily happenings. It does so inspired by philosophical-theoretical-methodological flows in the field of qualitative research where working against colonial ways of knowing and justice-oriented knowledge creation is of importance. The article's storying evolves from a reality- and philosophy-driven curiosity of race in relation to professionalism in early childhood education in a Nordic landscape. As a way of thinking through how to perform critical qualitative inquiry when positioned in a monist materialist thinking and within a philosophy of desire (Deleuze & Guattari, 1983, 1987), it explores Braidotti's (2011, 2013) “affirmative critique” as a way of working creatively with resistance.
Chicana/Latina Feminist Critical Qualitative Inquiry
Authors: Saavedra Cinthya M. , Pérez Michelle Salazar
Published: January 2018

In this article we take a journey into using Chicana/Latina feminisms as one way to unearth new possibilities for critical qualitative inquiry (CQI). We start by offering a brief overview of Gloria Anzaldúa's influence on Chicana/Latina feminism, focusing on how she has inspired researching and writing from within rather than about as a decolonial turn (Keating, 2015). We then venture into new imaginaries to pose questions that would lead us to ponder about global feminista solidarity, the spirit, and the land. Our hope is that these contemplations lead us on a path of conocimiento where we can put the broken pieces of our/selves back together again.
The Tryout of Dance Teaching Media in Public School in The Context of Appreciation and Creation Learning
Authors: Malarsih Malarsih
Published: January 2018

Dance learning through appreciation and creation approach is considered important in public school. This study is aiming at realizing dance media to be used as a tool to educate students as formulated in the school curriculum. Specific target to be accomplished in this study is the realization of dance learning media as one of appreciation and creation educational tool in public school. Further, this study employed developmental research method. The tryout of the product was done to measure the effectivity and creativity of students while the media is implemented in dance learning. The product’s trial result showed that the use of dance learning media that was designed specifically for appreciation and creation approach has succesfully driven the students to be more active and creative. Teacher assistant was less needed by students whenever they have problems related to the dance learning.

How to Cite: Malarsih. (2016). The Tryout of Dance Teaching Media in Public School in The Context of Appreciation and Creation Learning. Harmonia: Journal of Arts Research And Education, 16(1), 95-102. doi:http://dx.doi.org/10.15294/harmonia.v16i1.4561
The Role of Stakeholder in Fostering Traditional Art Awareness (A Case Study of Sundanese Local Song ‘Cianjuran’ Artist Training in Sumedang Regency West Java, Indonesia)
Authors: Julia Julia
Published: January 2018

This paper examines the process of seeding or training of Sundanese Song Cianjuran by artists in Sumedang regency that is conducted by a stakeholder of Sundanese traditional arts. The study was conducted using descriptive analytic methods, and data collection was done through observation and interviews. Results from the study explained that stakeholder participation was vital and influential towards the existence of Sundanese Song Cianjuran, especially in growing cultural awareness and in generating candidates for local traditional artists.

How to Cite: Julia. (2016). The Role of Stakeholder in Fostering Traditional Art Awareness (A Case Study of Sundanese Local Song ‘Cianjuran’ Artist Training in Sumedang Regency West Java, Indonesia). Harmonia: Journal of Arts Research And Education, 16(1), 87-94. doi:http://dx.doi.org/10.15294/harmonia.v16i1.6005

 
Building Creative Art Product in Jombang Regency by Conserving Mask Puppet
Authors: Yanuartuti Setyo
Published: January 2018

Building creative industry is one the effort chose to keep up with the ongoing of era development. Traditional art is one of the resource to produce creative art products. Gate Duwur Mask Puppet is a mask performance in Jombang Regency East Java that contains local wisdom. The local wisdom was one of the creativity sources to develop creative art products in Jombang Regency because maintaining Jati Duwur Mask Puppet performance was hard in the middle of the fast society development. The transformation of the source culture (mask puppet) to become the current target culture is one of the efforts made to build creative art. The research on mask dance conservation on mask puppet performance in Jombang was needed. The research method used was an art development through conservation. There were three products of mask dance created as a result of this research. The dances were Gladhen dancers – a couple dance, Mbanmban mask dance – a theatrical group dance, Maduretno-citralanggenan dance – a dance fragment. These mask dance products were a creative realization of a mask performance originated from mask puppet. The community and mask, puppet performer agreed to the development of mask dance to become a more creative art product that could be enjoyed by the young generation.
Banyumasan Songs As Banyumas People’s Character Reflection
Authors: Suharto S. , Sumaryanto Totok , Ganap Victor , Santosa Santosa
Published: January 2018

This study aims to identify a number of legendary Banyumasan songs. The fact that a large number of the songs exist and people sing the songs all the time shows that the songs have their own uniqueness. This study takes place in Banyumas regency. By doing performance study and composition, this study identifies the form and the structure of Banyumasan songs, and the moral value of Banyumasan music, especially the songs in Banyumasan music. The result of the study shows that the songs in the art performances in Banyumas commonly use classic immutable songs. The lyrics in the classic Banyumasan songs use Ngoko Javanese in Banyumasan dialect. The rhyme of the lyrics is usually in the form of wangsalan, parikan, and Essen-Essen. The rhyme contains funny and entertaining riddles. The lyrics of Banyumasan songs reflect Banyumas people’s character and the dream/utopia of the people’s ideology. The character is shown in the use of ngoko Javanese in Banyumas dialect which shows that the society is blakasuta or egalitarian who considers all people in the world has the same level and must be honest.

How to Cite: Suharto, S. (2016). Banyumasan Songs As Banyumas People’s Character Reflection. Harmonia: Journal of Arts Research And Education, 16(1), 49-56. doi:http://dx.doi.org/10.15294/harmonia.v16i1.6460
The Cultural Identity of Nusantara in a Movie Entitled Sang Pencerah by Hanung Bramantyo
Authors: Puspitasari Dyah Gayatri , Sabana Setiawan , Ahmad Hafiz Aziz
Published: January 2018

Nowadays, during this intercultural era and global challenge, film can be interpreted as a practical strategy to develop meaning and Indonesian cultural identity. Through many singers of audiovisual creation, film has not only served as entertainment, but can also act as an instrument to reflect local values and traditional perspective through the storytelling that has been presented by film director. This role is a significant point to develop local insight and cultural value as the identity of Indonesian film. Although, at some point, this strategy still becomes a problem in Indonesian film fields. Sang Pencerah film that was directed by Hanung Bramantyo is one of Indonesian films that attempted to deliver local identity in its storytelling. This research is an endeavour to identify Indonesian cultural identity that has been represented through Sang Pencerah film. By applying cultural studies and interdisciplinary as their methods, the researchers acquired some interesting findings. Firstly, aesthetic and thematic elements in the film narrative had a significant relation to traditional and cultural values of Javanese society. Secondly, the meaning of cultural identity also had a linear proportion to spiritual values in life, such as determination, peacefulness, gloriness, tolerance, as well as social understanding. Therefore, it can be concluded that the Sang Pencerah film is a manifestation of Hanung Bramantyo regarding to the meaning of Indonesian culture that is based on Javanese society’s local wisdom.

How to Cite: Puspitasari, D. G., Sabana, S., & Ahmad, H. A. (2016). The Cultural Identity of Nusantara in a Movie Entitled Sang Pencerah by Hanung Bramantyo. Harmonia: Journal of Arts Research And Education, 16(1), 57-65. doi:http://dx.doi.org/10.15294/harmonia.v16i1.6768
The use of value clarification technique-based- picture story media as an alternative media to value education in primary school
Authors: Fariyatul Eni , Bandono Adi
Published: January 2018

Developing learning media by adjusting it to the subject materials’ characteristics and students’ development needs to be done. Based on this concern, this research is aiming at developing picture story media that is based on value clarification technique (VCT) as an alternative value education in primary school. This research employed Research and Development (R & D) study approach and specifically adapted the study model from Dick and Carey (2001). Data collection was done through documentation note, observation, questionnaire, and try out. Data that had been collected then was analysed by using qualitative and quantitative methods (mix methods). Based on the try out result, it shows that the picture story media that is being developed has fulfilled the criteria of validity, effectivity, and practicality. Besides, based on the observation results of the tests’ try out process, it shows that the media has given positive impact towards the expected learning process and results.
The impact of 27-hydroxycholesterol on endometrial cancer proliferation
Authors: Gibson Douglas A , Collins Frances , Cousins Fiona L , Esnal Zufiaurre Arantza , Saunders Philippa T K
Published: January 2018

Endometrial cancer (EC) is the most common gynaecological malignancy. Obesity is a major risk factor for EC and is associated with elevated cholesterol. 27-hydroxycholesterol (27HC) is a cholesterol metabolite that functions as an endogenous agonist for Liver X receptor (LXR) and a selective oestrogen receptor modulator (SERM). Exposure to oestrogenic ligands increases risk of developing EC; however, the impact of 27HC on EC is unknown. Samples of stage 1 EC (n = 126) were collected from postmenopausal women undergoing hysterectomy. Expression of LXRs (NR1H3, LXRα;NR1H2, LXRβ) and enzymes required for the synthesis (CYP27A1) or breakdown (CYP7B1) of 27HC were detected in all grades of EC. Cell lines originating from well-, moderate- and poorly-differentiated ECs (Ishikawa, RL95, MFE 280 respectively) were used to assess the impact of 27HC or the LXR agonist GW3965 on proliferation or expression of a luciferase reporter gene under the control of LXR- or ER-dependent promoters (LXRE, ERE). Incubation with 27HC or GW3965 increased transcription via LXRE in Ishikawa, RL95 and MFE 280 cells (P < 0.01). 27HC selectively activated ER-dependent transcription (P < 0.001) in Ishikawa cells and promoted proliferation of both Ishikawa and RL95 cells (P < 0.001). In MFE 280 cells, 27HC did not alter proliferation but selective targeting of LXR with GW3965 significantly reduced cell proliferation (P < 0.0001). These novel results suggest that 27HC can contribute to risk of EC by promoting proliferation of endometrial cancer epithelial cells and highlight LXR as a potential therapeutic target in the treatment of advanced disease.
Benamių asmenų gyvenimo patirtis ir savęs vertinimas
Authors: Poškaitė Rūta , Petružytė Donata
Published: January 2018

Šiame straipsnyje pristatomo tyrimo tikslas – atskleisti benamių asmenų patirties ir savęs vertinimo sąsajas. Siekiama ne tik apskritai ištirti benamių asmenų savęs vertinimą, bet ir išsiaiškinti, kaip benamių savęs vertinimas susijęs su jų socialinėmis ir demografinėmis charakteristikomis, šeiminiais ryšiais ir benamystės patirtimi. Pirmoje straipsnio dalyje aprašoma savęs vertinimo samprata bei benamių asmenų savęs vertinimo ypatumai. Antroje – pagrindinėje – dalyje pristatomi benamių apklausos, atliktos Vilniaus ir Panevėžio miestuose, rezultatai.Tyrimas padėjo atskleisti ne tik bendrą benamių asmenų charakteristiką, bet ir parodė jų savęs vertinimo lygį. Išsiaiškinta, kad benamių asmenų savęs vertinimas yra žemas arba vidutinis. Benamiai asmenys, nors ir pakankamai teigiamai žiūri į save, linkę sutikti, kad kartais jaučiasi nieko verti, ir norėtų labiau save gerbti. Benamiai asmenys, nors ir sutinka, kad turi gerų savybių, darbus atlieka taip pat gerai kaip ir kiti, tačiau įsitikinę, kad turi nedaug kuo didžiuotis. Benamių asmenų savęs vertinimas statistiškai reikšmingai susijęs su alkoholio vartojimu. Daugiau alkoholio vartojantys asmenys pasižymi žemesne saviverte. Benamių asmenų savęs vertinimas statistiškai reikšmingai susijęs su sveikatos įverčiu. Blogesne sveikata besiskundžiantys benamiai asmenys turi žemesnę savivertę. Savęs vertinimas statistiškai reikšmingai susijęs su išsilavinimu. Aukštesnį išsilavinimą turintys asmenys save vertina geriau. Tyrime nebuvo gauta statistiškai reikšmingų benamių asmenų savęs vertinimo ir socialinių ryšių duomenų. Vilniaus ir Panevėžio benamių asmenų savęs vertinimas statistiškai reikšmingai skiriasi. Panevėžyje gyvenančių benamių savivertė yra žemesnė nei gyvenančių Vilniuje. Tai gali lemti, kad Panevėžyje benamiai vartoja statistiškai reikšmingai daugiau alkoholio ir skundžiasi prasta sveikata.
Construindo cenários de simulação: pérolas e armadilhas
Authors: Neves Fabio Fernandes , Pazin-Filho Antonio
Published: January 2018

AIMS: By means of a literature review, this article aims to organize concise guidelines for the construction of scenarios for simulated training, discussing practical aspects of the application of this methodology in the health area.METHODS: Search were made in PubMed, Web of Science and LILACS databases, including articles in English, Spanish and Portuguese, published between August 1997 and July 2017. The descriptors used were “scenario-based training”, “scenario-based simulation”, “scenario preparation”, “script development”, “simulation scenario”, and “case-based teaching”, and their equivalents in Portuguese and Spanish. The search was delimited for review articles, practical guidelines, comments, editorials and letters to the editor. The descriptors were identified directly from articles, since they were not yet included in the subject indexes of databases or in the Medical Subject Headings. Only articles dealing with the methodology of simulation scenario construction were included.RESULTS: From 1,128 studies assessed, we selected 20 that met the inclusion criteria. Most of studies dealt with specific clinical situations, not discussing the methodology of scenario construction. The analysis of the 20 studies made it possible to develop guidelines for scenario construction, which were divided into three sections: building a scenario in eight steps, pearls in the construction of simulation scenarios and pitfalls in the development of scenarios.CONCLUSIONS: Construction of simulation scenarios should be planned and structured according to the proposed learning objectives, which should be clear and synergistic with the curricular content. In addition, it is fundamental to adjust the degree of fidelity of the scenario to the learning objectives, because excessively produced scenarios are expensive and can produce excessive fascination, dispersing the attention of the student. On the other hand, low fidelity scenarios can make it difficult for participants to immerse themselves in the activity. Like any project, resources must be invested in planning to facilitate its execution and, consequently, to increase its effectiveness.
Centros de simulação e projeto pedagógico: dois lados da mesma moeda
Authors: Brandão Carolina Felipe Soares , De Carvalho-Filho Marco Antonio , Cecilio-Fernandes Dario
Published: January 2018

OBJETIVOS: Discutir as principais questões relacionadas ao uso e estruturação de um centro de simulação: logística, aproveitamento dos recursos e alinhamento entre o projeto pedagógico e as atividades simuladas.MÉTODOS: Revisão narrativa da literatura, com busca nas bases de dados Web of Science, PubMed, SciELO e Google Scholar, incluiu artigos publicados até junho de 2017.RESULTADOS: A simulação médica tem sido inserida nos cursos da área de saúde tanto para treinamento quanto para avaliação. Com isso, houve um grande aumento de centros de simulação, os quais envolvem um alto custo tanto para sua infraestrutura geral e especificidades como para manutenção. Muitas vezes os centros de simulação têm uma baixa aceitação docente e discente, tornando-os subutilizados, principalmente quando a metodologia não é implementada adequadamente. O método será mais valorizado quando houver um alinhamento entre o projeto pedagógico e as atividades simuladas. O planejamento de um centro de simulação é uma tarefa árdua que exige estudo prévio, conhecimento sobre o currículo institucional, orçamento e visitas a outros centros já existentes para evitar grandes ajustes posteriores que potencialmente são difíceis e onerosos. Para um melhor aproveitamento logístico, é necessário inicialmente identificar o público alvo e a inserção curricular do método, para definir a quantidade de participantes, tipos de salas e tipos de simuladores. A capacitação docente e o envolvimento multiprofissional são necessários para o bom funcionamento do centro de simulação, sendo que um dos principais motivos para a sua subutilização é a falta de capacitação docente. Além de capacitar os docentes, outras formas para utilizar os centros de simulação estão relacionadas à pesquisa e à parceria entre escolas de medicina e serviços hospitalares. Nessa parceria, as instituições de ensino ganham oportunidades de financiamento e interação com a sociedade, enquanto os hospitais ganham qualificação e aumentam a segurança de seus pacientes. Todas essas questões devem ser consideradas quando o estudo orçamentário é realizado, pois apenas o ambiente físico e os simuladores não são suficientes para o aproveitamento do ambiente simulado.CONCLUSÕES: A integração entre educação, pesquisa e assistência, e o alinhamento com o projeto pedagógico, são de extrema importância para a utilização da simulação na área da saúde, e essenciais para o desenvolvimento de novos treinamentos e conhecimentos.
Debriefing as an opportunity to develop emotional competence in health profession students: faculty, be prepared!
Authors: De Carvalho-Filho Marco Antonio , Schaafsma Evelyn S. , Tio René A.
Published: January 2018

AIMS: In this article, we want to share our perspective on how simulation sessions could contribute to change reality, building a safe environment in which facilitators can role-modeling students to develop emotional competence. Noteworthy, acknowledging and legitimating emotions are also essential components of creating a safe environment for students. We also intend to stress how faculty development programs are essential to guarantee that facilitators will be prepared to accomplish this new learning goal, and how different cultural contexts can influence the process.METHODS: In this narrative review, we will focus on the importance of emotions. Emotions in the context of learning but also learners’ emotions from the viewpoint of teachers, and teachers’ emotions in the context of faculty development.RESULTS: Simulation in medical education is becoming increasingly important. Advances in technology give many opportunities to simulate almost anything you want, with high fidelity and enhanced reality. It creates the possibility of bringing the complexity of real clinical tasks to a controlled simulated environment. While performing these complex simulated tasks, students experience several and sometimes distinct emotions: the emotions of patients and their families, the emotions of the multi-professional team members, and their own emotions, as learners and as future health professionals. Unfortunately, the formal curricula of the majority of medical schools do not address the importance of emotional competence specifically, and students end with the general impression that emotions are mainly negative, and must be avoided and kept at a safe distance. However, there are plenty of data showing how emotions can influence learning and decision-making, and how important it is to create awareness of and modulate them to guarantee the safeguard of patients’ interests.CONCLUSIONS: Emotions directly affect several dimensions of clinical work, such as communication, decision-making, teamwork, and leadership. We hope that including dealing with emotions as a natural goal of the learning activities in the health professions can catalyze the reconciliation between the technical and emotional aspects of clinical practice.
Clinical simulation and patient safety: integration into the nursing curriculum
Authors: Escudero Eliana , Ben-Azul Marcela Avendaño , Dominguez Cancino Karen
Published: January 2018

AIMS: To present the experience of creation, development and results of a nursing curriculum that integrates clinical simulation and patient safety with its challenges and achievements after four generations of graduates.EXPERIENCE DESCRIPTION: The School of Nursing at the Finis Terrae University is the result of a direct request from the authorities of the institution at a time when the country required an increase in the supply of nursing professionals. It started with a project that in the course of its development and implementation require several adjustments in programmatic terms. From its beginning, the project takes into consideration the integration of simulation and sets security at the heart of development. For this, we worked on new instruments that established how to implement the educational process, generating a model of teaching based on simulation, together with the establishment of control points that allowed the application of the model of continuous improvement. Through its development, seals are configured that differentiate the nursing student in the national environment. We are currently working to comply with international standards, periodically reviewing the implemented strategies and the way we teach for the benefit of our students. We consider as challenges the generation of interprofessional work, the strengthening of the teaching staff, and the generation of research, that demonstrate the benefits of having a curriculum for security based on simulation considering our local reality.CONCLUSIONS: The integration of simulation and patient safety in the nursing career curriculum is a challenge that requires the implementation of innovative processes, mobilizing resources of all kinds to achieve the goal. Strengthening leadership, clinical judgment and quality of nursing professionals deserve this kind of change. We believe changes like this in nursing education will enable us to achieve better health outcomes worldwide.
El taller profesional de gráfica De las técnicas tradicionales a la impresión digital 3D
Authors: Ruiz Martín José Manuel
Published: January 2018

El taller profesional de reproducción, ligado al campo artístico del grabado y la gráfica, ha sufrido una transformación convulsa durante los dos últimos siglos, especialmente desde que las tecnologías digitales aparecieran. El grabado y sus técnicas derivadas ofrecieron una respuesta directa a las necesidades editoriales de varios siglos, permitiendo al artista gráfico desarrollar nuevos lenguajes y procesos que se transformaron con la aparición de la máquina automática. Primero, fue la fotocopiadora y su lenguaje electrográfico; después, los nuevos dispositivos digitales de registro e impresión. Con ello, el taller deviene laboratorio, un lugar dotado de nuevas tecnologías donde el artista experimenta nuevas posibilidades creativas. Así, el presente artículo plantea un recorrido histórico-conceptual no acometido hasta la fecha: la evolución y transformación del taller de reproducción gráfica, lo que aporta una idea precisa del bagaje y las relaciones concretas entre lo analógico y lo digital en el terreno artístico de lo gráfico.
Análise físico-química e microbiológica de água de poços artesianos em um município do Vale do Taquari-RS
Authors: Macedo Tatiane De Lourdes , Rempel Claudete , Maciel Mônica Jachetti
Published: January 2018

A água ingerida precisa estar em condições físico-químicas e microbiológicas adequadas pois trata-se de um constituinte importante para o organismo e é imprescindível para a sobrevivência dos indivíduos. Este trabalho objetivou analisar a qualidade físico-química e microbiológica em água de poços artesianos localizados em um município do Vale do Taquari-RS. Foram selecionados quinze poços artesianos para a verificação destes parâmetros, tais como: pH, condutividade, oxigênio dissolvido, temperatura, turbidez, colorimetria, coliformes totais, termotolerantes e contagem de bactérias mesófilas, comparando os resultados com os estabelecidos pela legislação vigente. Dentre os poços analisados, o poço n° 4 apresentou valores maiores de coliformes totais e termotolerantes. Em relação as análises de bactérias heterotróficas todas as amostras apresentaram resultados em desacordo com a legislação. Quanto as análises físico-químicas todas encontram-se dentro das normas estabelecidas. Ao analisar a qualidade da água em poços artesianos pode-se observar variações nos parâmetros possivelmente pelo mês que foi coletada as amostras e por fatores ambientais. Desse modo, este estudo sugere um melhor gerenciamento destes poços, pois mesmo com a cloração, estes ainda apresentam altos níveis de contaminantes.
Influência de parâmetros operacionais sobre as populações oxidantes de amônia e desnitrificantes em wetland construído vertical
Authors: Pelissari Catiane , Guivernau Miriam , Ávila Cristina , Viñas Marc , García Joan , Sezerino Pablo Heleno
Published: January 2018

O objetivo deste estudo foi avaliar a dinâmica das populações oxidantes de amônia e desnitrificante em um wetland construído vertical (WCV) operado com distintas condições operacionais. O WCV possuía uma área superficial de 3 m², dividida em duas células (1,5 m² cada) interconectadas, preenchido com areia e brita como material filtrante e plantado com Phragmites australis. Durante o a realização do estudo (jun/15-jul/16), as condições operacionais do WCV variaram em função de três períodos operacionais: Período I (130 g DQO m-2 d-1; 375 mm d-1; ciclos de alimentação e repouso de 3,5 dias), Período II (80 g DQO m-2 d-1; 375 mm d-1; ciclos de alimentação e repouso de 3,5 dias) e Período III (40 g DQO m-2 d-1; 133 mm d-1; alimentação diária). Ao término de cada período foram coletadas amostras do maciço filtrante na superfície e no fundo, de uma das células do WCV, bem como foi empregada a técnica de qPCR (em nível de DNA e RNA) para identificar a abundância e atividade de amoA de bactérias oxidantes de amônia (AOB), amoA de arqueas oxidantes de amônia (AOA) e nosZ de bactérias desnitrificantes. Indiferente das condições operacionais do WCV, AOB sempre foram mais abundantes que AOA. Contudo, em nível de expressão gênica, AOA foram mais ativas que AOB, sendo populações chave no processo de oxidação da amônia. Bactérias desnitrificantes foram identificadas mais ativas na superfície, quando o WCV operou com alta carga orgânica. Com menor carga orgânica aplicada, uma maior atividade desnitrificante passou a ser identificada no fundo do wetland.
Avaliação dos dois primeiros anos de operação de um wetland construído vertical	de fundo saturado aplicado no tratamento de esgoto sanitário
Authors: Santos Mayara Oliveira dos , Pelissari Catiane , Rousso Benny Zuse , Freitas Monique Nunes de , Sezerino Pablo Heleno
Published: January 2018

Este artigo apresenta o desempenho de remoção de poluentes promovido por um wetland construído vertical de fundo saturado (WCV-FS), empregado no tratamento de esgoto sanitário, ao longo de 21 meses de operação e monitoramento. O WCV-FS (7,5 m² de área superficial) possui uma profundidade de 75 cm, com os últimos 40 cm saturados com esgoto, areia como material filtrante e plantado com Typha domingensis. A alimentação foi realizada de forma intermitente (4 pulsos d-1), com um regime hidráulico baseado em ciclos de alimentação e repouso de 3,5 dias na semana. Durante o estudo (junho/15 - março/17), o WCV-FS operou com uma carga orgânica média de 41 g DQO m-2 d-1 e taxa hidráulica de 80 mm d-1. O WCV-FS apresentou elevada remoção de matéria orgânica carbonácea em termos de DQO (91 %) e sólidos suspensos (96 %), apresentando um desempenho de tratamento similar aos sistemas híbridos de wetlands avaliados no estado de Santa Catarina. Em relação ao nitrogênio total, a remoção média foi de 45 %, podendo estar associada com os processos de nitrificação e desnitrificação sequencial na mesma unidade de tratamento.