bluuebunny/crossref_metadata_2025 huggingface dataset:
The combined supplementation of omega-3 fatty acids and probiotics decreased the levels of serum polyamines in experimental colitis
Authors: Yoldaş İlktaç Havvanur , Büyükuslu Nihal , Parlayan Cüneyd
Published: October 2021

Polyamines play an important role in the maintenance of intestinal permeability. Therefore we aimed to determine the effects of probiotics and omega 3 fatty acids on serum polyamine levels in colitis. Fifty BALB/c mice were randomly grouped as normal, colitis with no treatment applied, colitis treated by probiotics (VSL#3), colitis treated by omega-3, and colitis treated by both probiotics and omega-3. Experimental colitis was induced by injection of 200 mg/kg 2,4-Dinitrobenzenesulfonic acid (DNBS). The probiotic and the omega-3 fatty acid supplements were applied daily by oral gavage. Serum polyamine levels were measured with high performance liquid chromatography (HPLC). In each group, the levels of serum polyamines are the highest in spermidine and the least in spermine. Bowel inflammation in experimentally induced colitis mice resulted in lower serum polyamine concentrations. In probiotic and omega 3 fatty acid supplemented group significant decreases were observed for spermine and spermidine (p<0.001), while no significant changes were obtained for putrescine. Combined supplementation of probiotics and omega-3 fatty acids for 10 days in colitis mice significantly decreased the serum levels of spermine and spermidine.
Civil legal method of protection of intellectual property rights
Authors:   National University of Life and Environmental Sciences of Ukraine, Oleksandr Svitlychnyy , O.M. Korotun ,   Judge of the Northern Commercial Court of Appeal
Published: October 2021

The article draws attention to the specifics of protection of intellectual property rights in Ukraine by civil and special legislation, the rules of which are designed to protect the subjective rights of right holders and other participants in legal relations in the field of intellectual property. Some aspects of the legal nature of jurisdictional remedies are studied. Attention is paid to the specifics of protection of intellectual property rights by civil law, which consists primarily in the methods of protection provided by procedural law. The legislation, the norms of which guarantee the protection of intellectual property and the ways of protection of civil rights are outlined. The existing in the legal literature different views on the classification of methods of protection of property rights are analyzed. The legal analysis of the application of the vindication claim as a means of protection of intellectual property rights is carried out and the author's proposals are formulated. Keywords: civil law, intellectual property, lawsuit, protection
Information support of scientific research: legal aspect
Authors:   Ukrainian Research Institute of Special Equipment and Forensic Science of the Security Service of Ukraine, O.M. Hres
Published: October 2021

The article considers the concept of «information», its interpretation and definition by both scientists and the Law of Ukraine «On Information». The main principles of information relations are presented. The main directions of the state information policy are noted. The key types of information are covered. Definition and legal regime of scientific and technical information are presented. It is indicated that scientific and technical information covers the results obtained in the process of scientific and research, research and development, design and technological, production and public activities, recorded in a form that ensures their reproduction, use and dissemination. It is stressed the need to expand the direction of information development, not limiting this area only by technical component of scientific activity and ignoring the humanitarian direction, because the information concerning scientific activity in general, including in the humanities, in the sphere of social sciences and in other scientific spheres is left out of consideration. It is noted that the main base of the scientific and technical information is formed with information resources, which are a systematic collection of scientific and technical literature and documents (books, brochures, periodicals, patent and design documentation, industrial catalogs, deposited manuscripts, scientific and research reports) fixed on papers or other storages. The main types of information activities and areas of information are given. The importance of information support in conducting scientific research is indicated and the search for the necessary information is of great significance for the effective conduct of scientific research, as the researcher spends about 50 % of his time on the process of finding information. The importance of the information for humanity is highlighted. Keywords: information, information support, science, scientific researches
The effect of an enrichment unit on climate change awareness and basic science process skills among gifted female primary school students
Authors: Saeed Sanad Fatema , Ahmed Aljasim Fatima , Soud AlHendal Huda
Published: October 2021

This study investigated how introducing climate change-themed lessons into the curriculum of gifted primary school females in Bahrain affected Climate Change Awareness and Basic Science Process Skills. Students included Students included 40 gifted sixth grade females divided into two groups: a 20-student experimental group and a 20-student control group. Basic Science Process Skills Activities and Climate Change Awareness Scale were used as the pre- and post-test to measure the science skills and climate change awareness among both groups. The experimental group received the enrichment unit. The Mann-Whitney & Wilcoxon tests showed that Significant differences emerged between experimental and control groups on the climate change awareness scale, but not in the behavioral domain of the scale. Possible explanations are included.
The effect of exploitation strategy on concurrent thinking ability abilities of students in Saudi Arabia
Authors: Abdelaziz Abdeen Samar
Published: October 2021

The purpose of this study was to measure the effect of the exploitation Strategy in enhancing concurrent thinking ability of student. This study used a quasi-experimental method. The study sample in this research consisted of students who attend the Taibah university in Saudi Arabia, the study sample was chosen intentionally. The total sample number was fifty students. Who were divided equally into two group control (25 student) and experimental (25 student). Instrument was used concurrent thinking test for Abdeen, which assessed the student’s level of concurrent thinking ability. This instrument was used to assess the skills pre and post the application of. The data for this research were collected by using quantitative method. The result of this study showed a significance difference in developing the concurrent thinking of the students between the control and experimental groups after the application. The results also indicate that the student concurrent thinking ability were significantly enhanced after the application of the exploitation Strategy. This study confirmed that concurrent thinking can be enhanced through specialized Strategies, which target the development of concurrent thinking ability, considering these finding the study recommended conducting further research and studies to develop concurrent thinking.
The Use of Fenugreek Supplementation in Diabetes
Authors: Mosawi Aamir
Published: October 2021

Dietary health supplements have increasingly used in the prevention and treatment of chronic disorders. During the previous decades, fenugreek (Trigonella foenum-graecum) seeds have been reported to have hypoglycemic and cholesterol lowering effects when used in type 1 and type 2 diabetes mellitus patients, and in experimental diabetic animals. The aim of this paper is to review fenugreek research findings relevant to its use in diabetes. There is convincing research evidence suggesting that fenugreek can improve hyperglycemia and has a protective effective against diabetic complications through immunomodulatory, insulin stimulation, and antioxidant effects, enhancing adipocyte differentiation, inhibition of inflammation in adipose tissues, and preventing or lessening pancreatic and renal damage. Many of the beneficial effects of fenugreek in diabetes have been attributed to four bioactive components including diosgenin, 4-hydroxyisoleucine, furostanolic saponins, and the fiber in fenugreek.
The Morpho-Genetic Estimation of Drought Stress in Sunflower Seedlings under Laboratory Conditions
Authors: Ayaz Uzma
Published: October 2021

Drought stress directly affects the growth along with productivity of plants by altering plant water status. The present study was carried out to characterize the genetic variability for seedling and morpho-physiological parameters in different sunflower genotypes under water stressed conditions. A total twenty seven genotypes including two hybrids, eight advanced lines and seventeen accessions of sunflower (Helianthus annuus L.) were tested against drought stress at seedling stages by applying Polyethylene glycol (PEG). Significant means were calculated among traits using analysis of variance (ANOVA) whereas, correlation and principle component analysis also confirmed that germination percentage, root length, shoot length, chlorophyll content, stomatal frequency are positively linked with each other hence, these traits were responsible for most of variation among genotypes. The cluster analysis showed that genotypes Ausun, line-1, line-2, line-3, 17578, 17570, line-6, line-7 and 17562 are more diverse among all the genotypes.
A Congolese infant of 4 months and 8 days presenting a severe form of Covid-19
Authors: Bodi Joseph
Published: October 2021

To date, only a few rare cases of severe forms of Covid-19 in children, especially infant, have been described in other parts of the world. So far no case reported in sub-Saharan Africa (SSA). We report the case in the Democratic Republic of Congo of an infant of 4 months and 8 days old, who presented after malaria disease, a picture of bronchopneumonia with severe respiratory failure (Pa O2 :49 mmHg). The RT-PCR made it possible to diagnose a Covid-19 of severe form. The infant had probably been infected by his mother and had no other co-morbidities that could induce a decrease in immunity. The CT scan injuries were comparable to those described in adults. Under oxygen, anticoagulation, hydroxychloroquine and Azythromycin, the outcome was good. Pediatricians in SSA countries should be careful and not miss cases of COVID19 in infant population with severe respiratory syndrome usually observed in most of lung infectious disease.
Attacks on the precious truffles by useful and harmful invadors
Authors: Elkhateeb Waill
Published: October 2021

Truffles are ectomycorrhizal mushrooms that grow in specific climates. They are rare and famous for their secondary metabolites and their promising biological activities. Truffles are considered from the most expensive macrofungi all over the world. Understanding the rare and uncommon types of interaction between truffles and their different invadors is of high significance. However, studies describing such relation are very limited. In this review, we describe general description and ecology of truffles. Examples on microbes attracted to colonize fruiting bodies of truffles were mentioned. Finally, factors causing truffles damage such as pathogenic fungal attacks, truffles rot, and insects’ invasion were highlighted.
Using Telemedicine for Providing Supportive and Palliative Care Patients with Advanced Cancer during the COVID?19 Pandemic in Ukraine
Authors: Mohammad I M Hojouj
Published: October 2021

COVID‐19 has overwhelmed the capacity of health care systems, limiting access to supportive and palliative care for patients with advanced cancer. Telemedicine has emerged as a tool to provide care continuity to patients while limiting the risk of contagion. However, implementing telemedicine in resource‐limited settings is challenging. We report the results of a multidisciplinary patient‐navigator‐led telemedicine supportive care program in Dnipro City. One‐hundred sixty‐five telemedicine interventions were provided to 50 patients (median age 67, 47% female). A quarter of the patients had less than or equal to elementary school education, and 18% lived in a rural area. The most common interventions were psychological care (30%), pain and symptom control (27%), and nutritional counseling (10%). Half of the interventions were provided by video conferencing. The most common patient‐reported barrier was limited experience using communication technology. Our results demonstrate the feasibility of providing supportive and palliative care interventions using telemedicine in resource‐limited settings.
A Decrease in the Increased Marker of Tissue Hypoxia Pco2> (Av-Gap) in Microcirculatory-Mitochondrial Distress Syndrome in Critical Obstetrics is Achieved by Complex Methods of Recruiting Microcircula
Authors: Ilie Vasiliev , Maria Vasilieva , Irina Vasilieva
Published: October 2021

Considering maternal mortality in state-of-the-art clinics and sophisticated methods of treatment and diagnosis, the human factor of the doctor and the available methods of treatment and diagnosis remained a priority in reducing and even eliminating obstetric mortality. The of success since the last century as in this century of which we described in this work, as in many other previously published works, and represented at international congresses in the Republic of Moldova, Romania, Spain, the Netherlands, Russia and others, where decrease in the increased marker of tissue hypoxia pCO2> (AV-gap) in microcirculatory-mitochondrial distress syndrome in critical obstetrics is achieved by complex methods of recruiting microcirculatory-mitochondrial distress syndrome, contributed to the absence of maternal mortality over 40 years of work in critical obstetrics is presented as a brilliant proof of an affordable model in any medical institution that finds itself next to a dying woman in labor.
Profile of Children Treated for Uncomplicated Intussusception in a Tertiary Hospital in Enugu, Nigeria
Authors: Kevin Emeka Chukwubuike
Published: October 2021

Background: Intussusception is a common cause of intestinal obstruction in infants. The aim of study was to evaluate our experience in the management of children who presented with uncomplicated intussusception. Materials and Methods: This was a retrospective study of children (12 months and younger) who were treated for uncomplicated intussusception (ultrasound confirmed) between January 2014 and December 2018, at the pediatric surgery unit of Enugu State University Teaching Hospital (ESUTH) Enugu, Nigeria. Results: There were 255 cases of intussusception seen during the 5-year study period. Out of this number, 85 (33.3%) patients had uncomplicated intussusception. There was male predominance and the ages of the patients ranged from 4 to 12 months with a mean age of 6 months. Abdominal pain was the most common symptom in the patients. On the average, one-fifth of the patients had a preceding history of respiratory and enteral infection. Half of the patients had a hemoglobin level of less than 10g/dl at presentation. Abdominal ultrasound was the imaging modality of choice and was diagnostic in all the patients. Three-quarters of the patients were successfully treated by hydrostatic reduction and there was recurrence of intussusception in 2 patients. There was no mortality. Conclusion: Only one-third of our patients present with uncomplicated intussusception during the study period. Non-operative (hydrostatic reduction) treatment is an effective modality of treatment for uncomplicated intussusception.
Measuring Harmony With Algebra: Collected Papers in Memory of Yakov Abramovich Sher
Authors: Chugunov K. ,   The State Hermitage Museum
Published: October 2021

Сборник посвящён памяти выдающегося российского археолога Якова Абрамовича Шера (1931–2019). Большинст- во публикуемых статей связано с анализом первобытного и древнего изобразительного искусства, изучение которого всегда было доминантой исследовательских интересов Я. А. Шера и являлось основным направлением его научной деятельности. Книга предназначена для археологов, историков, искусствоведов, музейных работников.
La neuroeducación y aprendizaje significativo. Estudio experimental en tres instituciones del nivel de básica primaria
Authors: Caroline Bibiana Coral-Melo  , Sonia Lucy Martínez-Rubio  , Nelly Esperanza Maya-Calpa  , Hna. Marianita Marroquín-Yerovi
Published: October 2021

La investigación se centró en dos líneas pedagógicas: la neuroeducación y el aprendizaje significativo. El estudio se realizó a través de un estudio experimental, con la participación de los estudiantes de las instituciones que vivieron la experiencia, a saber: Institución Educativa Ciudad de Ipiales, la Institución Educativa Municipal Libertad y Centro Educativo El Campanero que participó como control en el año 2019. Así las cosas, lo experimental consistió en determinar el efecto de la aplicación de 24 talleres fundamentados en la Neuroeducación, expresado en los favorables resultados del postest de la Batería Psicológica BAT-7 y en el buen rendimiento académico que obtuvieron los grupos experimentales frente al grupo control. El estudio experimental incluyó dos variables predictivas: la permanencia y la eficacia, con el fin de permitir verificar la hipótesis estadística: los dos grupos experimentales obtienen resultados estadísticamente significativos en la aplicación del postest de la batería psicológica BAT-7, la cual se aplicó en tres instituciones participantes. Los resultados obtenidos en el postest de la BAT-7 y en el rendimiento académico confirman el efecto del desarrollo y aplicación de las estrategias neuroeducativas.
Prácticas pedagógicas de los docentes de tercero y quinto de educación básica, en lenguaje, desde las Pruebas Saber en la Institución Educativa Concentración de Desarrollo Rural de Manaure, Cesar
Authors: Antonio Julio Villamizar-Jiménez  , Oscar Andrés Jiménez-Ordoñez  , Juan Camilo Castro-Mendoza
Published: October 2021

La investigación, desarrollada en cinco etapas, tuvo como objetivo, fortalecer las prácticas pedagógicas docentes en el área de lenguaje, desde los resultados de la Prueba Saber, en el nivel de educación básica primaria de los estudiantes de tercero y quinto grado en la Institución Educativa ‘Concentración de Desarrollo Rural’ en Manaure, Cesar. El paradigma fue el cualitativo, con un enfoque mixto y, como método, la Investigación Acción. La unidad de trabajo estuvo constituida por 60 estudiantes de tercer grado y 62 de quinto grado. Los instrumentos fueron una entrevista estructurada y un cuestionario. Se concluyó, dar relevancia a los aspectos evaluados en la Prueba Saber, revisar si están incluidos en la planeación curricular y evaluativa del área, generando espacios de reflexión y discusión académica como compromiso institucional, porque aportaron a la comprensión de cómo aprende el estudiante y de cómo se puede crear estrategias pedagógicas y evaluativas que contribuyan al proceso de aprendizaje.
ESKİ SİNEMA SALONLARI VE İZLEYİCİ DENEYİMLERİ ÜZERİNE BİR SÖZLÜ TARİH ÇALIŞMASI
Authors: İLBUĞA Emine Uçar
Published: October 2021

Bu çalışma, Türk sinemasının altın çağı olarak kabul edilen, 1960-1970’li yıllarda önemli kent mekânları olan sinema salonları ve o dönemde sinemaya giden izleyicilerin gündelik yaşamlarından, sosyalleşme süreçlerine uzanan yelpazede bu mekânların nasıl bir rol oynadığı konusunu temel alan sözlü tarih çalışmasına dayanmaktadır. Bu kapsamda 1960 ve 1970’li yıllarda Türkiye’nin farklı bölgelerinde sinemaya gitmiş olan 22 (12 kadın, 10 erkek) katılımcı ile derinlemesine görüşmeler yapılmıştır. Katılımcılara kartopu örneklemi ile ulaşılmış ve yarı yapılandırılmış sorularla yürütülen derinlemesine görüşmelerde geçmişte sinemaya gitme deneyimleri, sinema salonlarının mekânsal anlamı, sosyalleşme gibi, bireylerin bilinçlenmelerine ve farklı kültürlerle karşılaşmalarına olanaklar sunan sinemekân deneyimleri araştırılmıştır. Çünkü sinema salonları salt film gösterimi yapılan mekânlar olmanın ötesinde, aynı zamanda geçmişe ait deneyimlerin somutlaştığı yerler olarak izleyicilerin belleklerinde önemli yer tutmaktadır. Bu bakımdan çalışmanın kuramsal temeli, bellek/izleyici, mekân/izleyici deneyimleri üzerinden çerçevelenmiştir.
Versammlungsfreiheit vs. Recht auf körperliche Unversehrtheit ‒ Ist die Einschränkung von Grundrechten zur Bekämpfung der Corona-Pandemie angemessen?
Authors: Bachmann Lisa
Published: October 2021

Menschen sollten in einer Demokratie jederzeit für ihre Anliegen eintreten und kämpfen können bspw. mit einer Demonstration. Auch das Grundgesetz schützt dieses Bedürfnis durch die Versammlungsfreiheit (Art 8 GG). Aber was, wenn Demonstrationen zu Infektionshotspots werden, die anschließend möglicherweise Krankenhäuser überlasten und somit das Recht auf Leben in Gefahr gerät? Wenn in Zeiten einer Pandemie Grundrechte eingeschränkt werden müssen, dann ist es immer eine Entscheidung, die ein Dilemma aufwirft. Auch Schülerinnen und Schüler (SuS) werden durch die Medien, Diskussionen am Esstisch oder in der Klasse in die diese Entscheidungssituation gedrängt. Um hier ein differenziertes, fundiertes politisches Urteil fällen zu können, ist es sinnvoll im Unterricht sowohl die theoretischen Hintergründe den SuS näherzubringen und zu vertiefen, als auch das Urteil zu dieser Abwägung zu vertiefen und damit zu festigen. Um dies angemessen zu gestalten, ist ein kontroverses Thema, das bestenfalls auch in der Gesellschaft kontrovers diskutiert ist, notwendig, was hier durch die Abwägung von zwei zentralen Grundrechten gegeben ist.
GENDER IMBALANCE IN THE FIELD OF PROVIDING FORENSIC SERVICES FOR JUSTICE: CURRENT SITUATION IN UKRAINE AND INTERNATIONAL EXPERIENCE
Authors: Agapova О. , Shpak Yu.
Published: October 2021

Abstract. The article is dedicated to the issue of gender inequality in general, and in particular in the field of forensic expert support of justice, including the problem of vertical segregation of labor in leadership positions in state specialized institutions of Ukraine. The article outlines possible reasons for the existence of gender imbalance in the form of vertical segregation of labor in leadership positions in the field of employment and in the field of forensic expert support of justice, as well as examples of gender inequality manifestations. An analysis of previous researches of distinguished women scientists and representatives of civil society institutions as to the problem of gender imbalance in the field of education, professional self-determination and career growth has been carried out. A specific focus is drawn to particular manifestations of gender imbalance in science. At the same time, the analysis of legal regulations of national and international significance on counteraction to gender inequality in different areas of public life has been considered. The activity of central executive agencies regarding advancement of women in society and influence of initiated programs on counteraction to gender imbalance in the field of forensic expert support of justice is studied. Statistics on manifestations of possible vertical segregation of labor in leadership positions in state specialized institutions of Ukraine is provided. Examples of international organizations which activity has a wide range of influence and the ones which activity is aimed at improving the state of women forensic experts in the field of forensic expert support are outlined. The experience of such organizations for preventing and overcoming gender imbalance, as well as specific proposals for solving this problem are taken into consideration.
CRIME COUNTERACTION WITHIN THE SCOPE OF NETWORK APPROACH
Authors: Lytvynov O. , Spitsyna H.
Published: October 2021

Network management is a relatively new concept, which, nevertheless, has taken its place in the field of science and practice of crime counteraction management. In connection with recognition of the place and role of networks in implementing management activity, a number of theoretical questions on redefining the role of state, legitimacy of network structures, trust to new forms of interaction within the state, private sector, nonprofit organizations and associations of citizens arise. The issue of state sovereignty, legitimacy and trust in the context of management problems are studied not only by political scientists, but also by criminologists who conduct research on the problems of improving the policy of crime counteraction.
The majority of autonomous, independent and not subordinate to each other entities are involved, each of whom solves his task in this common problem by his own means and methods in accordance with corresponding legislation. However, no matter how independent and autonomous the participants in crime counteraction are, their division is unacceptable since each of them is only one part of the common state and legal system aimed at ensuring resolution of a single task in crime counteraction. Each of them, no matter how it works, is not able to address the issue of crime idependently, only by his own means. They only complement each other, and therefore their activity, undoubtedly, require organization, management, coherence, interaction, coordination. And one of the ways to organize the system of accomplishment of set tasks is network management. The peculiarities of the latter are that a certain part of crime counteraction happens primarily on a procedural basis, and law enforcement agencies are procedurally independent and autonomous (this excludes any authroitative forms of management). Therefore, network management is implemented only on the basis of equality of all its elements, independence of each of them when performing tasks, responsibility for their realization and compliance with law.
CONCEPTUAL ASPECTS OF THE USE OF BIBLIOMETRIC TECHNOLOGIES IN THE FIELD OF COUNTERACTION TO CRIMINAL OFFENSES IN THE AIRLINE INDUSTRY
Authors: Shynkarenko I. , Zakharov V. , Shynkarenko I. , Zakharova O.
Published: October 2021

The article specifies that systematic and complex scientific researches on problems of the use of bibliometric technologies in preventive activity regarding detection and neutralization of threats to entities-facilities of air transport, companies staff, institutions and organizations which work in this field have not been considered yet. The results of researches and scientific papers of representatives of the Ukrainian forensic community had been analyzed, which determined the need for theoretical-legal and forensic research in the field of identification and verification of a person with the use of biometric technologies to solve tasks of counteraction to crime and civilian tasks of managerial and controlling content. The article purpose is to define current problems of the development of the newest directions of biometric technologies use in counteraction to criminal and other types of offenses; formation of theoretical principles of algorithmization of the use of biometric technologies in preventive activity.
The use of the complex of general and special research methods has made it possible to identify factors and content of reasons and conditions for solving the present day tasks with the use of biometric technologies in security and preventive activities. Such approach has helped to draw the conclusion that the most promising directions of biometric technologies application are: security guaranteeing and ensuring access control to certain areas and space activity facilities; creation of a person identification systems; introduction of reliable and economic means of delimitation of access to the territory of facilities, buildings and internal premises of space activity entities; efficiency and personnel management; information protection of multifunctional user identification systems in information networks, operating systems, various add-ons for typical software.
Forensic support of the activities of forensic science institutions and pre-trial investigation and inquiry bodies in counteraction to crime
Authors: Yukhno O.
Published: October 2021

Pressing issues of forensic support of activities of pre-trial investigation and inquiry bodies in countering criminal offenses are outlined.
The concept and essence of crime counteraction are considered. The article analyzes the national criminal procedural legislation, departmental regulatory legal framework and their amendments concerning the direction under study, genesis of scientific findings on theoretical and applied issues of forensic support of the activities of pre-trial investigation and inquiry bodies in this direction, as well as the genesis of the concept and essence of forensic science as a science.
The modern state of the development of forensic science, current high-priority issues and feasibility of changing the scientific paradigm of forensic science as well as the use of innovations are studied; ways for their improvement are proposed. Theoretical and applied problematic issues of criminalistics are subject to thorough study and resolution. Fundamental changes are required both in criminalistics in general and in particular in its individual areas. The current legislation, law enforcement agencies, forensic science institutions, prosecutors’ bodies and judicial bodies, as well as law enforcement, in which modern advances in science and technology (in particular, computer and telecommunication technologies) are being implemented should be reformed. The article highlights such problematic issues as the improvement of the forensic characteristics of cer-tain types of crimes, forensic techniques combining forensic techniques and tac-tics. The issue of further implementation in law enforcement and forensic expert activities of promising molecular genetic examinations for pre-trial investigation bodies, including the method of DNA analysis is outlined separately and fully.
Relying on the results of research, specific author proposals and recommenda-tions are provided on the studied area of activity in general and in individual directions.
Impact of adenotonsillectomy on the quality of life of patients operated on at the Hospital de Clínicas, Paraguay
Authors: Mena Canata Carlos , Noemí Ruiz Vallejos Rebeca
Published: October 2021

The objective of this study is to determine the impact of adenotonsillectomy on the quality of life of postoperative patients.The study is observational, cross-sectional, and retrospective. The files of all postoperative adenotonsillectomy patients in Otorhinolaryngology Service, Hospital de Clínicas, San Lorenzo Paraguay. The Obstructive sleep apnea – 18 questionnaire (OSA 18) was applied, asking patients about symptoms before and after surgery. An effective sample of 143 postoperative patients was obtained. The average age was 6.05 ± 2.08 years, 55.10% (81) were male and 44.89% (66) were female, 65.30% (96) were from urban areas and 34.69% (51) from the rural areas. The t test was performed for means of two paired samples, comparing the results of the Obstructive sleep apnea – 18 questionnaire surveys before and after surgery which presented a significant difference (p <0.05) with a tendency to improve the quality of life after surgery. It has been shown that there is a significant difference, a considerable improvement in the quality of life of patients after adenotonsillectomy.
Vertebral metastasis of renal carcinoma at diagnosis. Mechanical and clinical evaluation. Surgical management
Authors: Merino-Rueda Luis Rodrigo , Martín-Fuentes Ana María , Ortega-García Francisco Javier , González-Díaz Rafael , Ramos-Pascua Luis Rafael
Published: October 2021

Renal cell carcinoma is among the 10 most common cancers. Metastatic disease of the spine is common and 50% of bone metastases are already present at the time of primary diagnosis. Bone metastases from renal cell carcinoma are difficult to manage, especially vertebral localization.
A 48-year-old woman was diagnosed with renal cell carcinoma in the context of low back pain. The patient presented two skeleton metastases at diagnosis (T11 and 5th rib). The patient received neoadjuvant treatment with cabozantinib, followed by removal of the renal tumor. Radiotherapy was administered for the lumbar lesion. In spite of the radiotherapy treatment, increased low back pain limiting mobility and ambulation. MRI showed an occupation of the spinal canal, without neurological lesion. The SINS scale revealed a score of 14 (vertebral instability). The patient's prognosis was greater than 12 months according to the Tokuhashi score. Based on clinical and mechanical criteria, surgical treatment of the vertebral lesion was decided. T11 vertebrectomy was performed, the reconstruction was made with an expandable cage, and T8 a L2 posterior spinal arthrodesis. A partial resection of the fifth rib was performed in order to remove the whole macroscopic tumor. After 3 months, she was diagnosed with a local infection, treated by irrigation, debridement and antibiotherapy, with good evolution. At 1-year follow-up, she has no low back pain or functional limitation. Follow-up chest-abdomen-pelvis computed CT scan showed absence of disease progression, furthermore, the vertebral arthrodesis shows fusion signs. At the time of this report, there are no clinical or radiological data of infection.
Odontogenic keratocyst: diagnostic characteristics and conservative surgical treatment
Authors: Sánchez Sánchez Javier , Aguilar Maldonado José , Barreno Haro Karem
Published: October 2021

Keratocyst is a benign odontogenic lesion with aggressive behavior, probably derived from the dental lamina. It is frequently located in the posterior part of the mandibular bone in the area of ​​the third molar, mandibular angle and can progress towards the ramus and the body, presenting a direct association with retained dental organs. There is a wide variety of techniques for the treatment of this lesion, such as decompression, marsupialization, enucleation, and en bloc resection, as well as the combination of these with adjuvant methods. The interest in this lesion stems from its high recurrence rate, which is estimated to be 20-30% in the general population, however, at present the use of conservative treatments such as marsupialization and decompression has been chosen. demonstrated greater effectiveness and less recurrence. This is why after treating the lesions it is important to give a long-term follow-up.
The objective of the publication is to present the report of a clinical case of a 21-year-old male patient with a diagnosis of odontogenic keratocyst treated with a decompression technique for five months for subsequent surgical enucleation. It has been proven that decompression treatment followed by enucleation and accompanied by adjuvant methods is an adequate therapeutic management for keratocysts as it demonstrates its lower rate of recurrence and its noble behavior with neighboring vital structures. However, in all cases, regular monitoring should be carried out to prevent recurrence of the lesion.
Analisis Kepatuhan Penggunaan Alat Pelindung Diri (APD) Pada Peserta Pelatihan Keterampilan Tukang dan Pekerja Konstruksi
Authors: Mafra Ramadisu , Riduan Riduan , Zulfikri Zulfikri
Published: October 2021

Compliance of personal protective equipment (PPE) uses without the impact of the consequences is a reflection of a good workforce. This compliance is thought to be influenced by various factors, such as knowledge, attitudes, years of service, comfort, suitability of PPE and type of work and availability. The phenomenon of non-compliance cannot be ignored, and is evident from several previous studies. This study aims to measure the level of compliance, reasons and factors that influence it. Involving 80 participants who participated in builder skills training. Collecting data using K3 logbook, surveillance camera recordings and field observations, the data were processed by cross sectional analysis to see causality and choreation. The results showed that the level of compliance using PPE correctly was 82.92% on average. The average level of compliance with individual behavior is 66.25%. Non-compliance with the use of PPE safety helmet 29.00%, cotton glove 19.38%, safety vest 16.25% and safety boot 3.44%, with reasons of forgetting 33.85%, PPE is considered to be disturbing 26.67%, feeling uncomfortable 26.15% and the attitude of feeling that they will not be harmed by 13.33%, which is influenced by the factors of unsafe work habits without PPE, years of service, the harmony of PPE types and work, and there is no relationship between knowledge and compliance with the use of PPE. Repetitive non-compliance did by 30,00% participants.
Information Support of Marketing Statistics of Innovative Enterprises
Authors:   University of Customs and Finance, Horiashchenko Yulia
Published: October 2021

Ukraine continues to actively develop a civilized business environment, including by means of marketing promotion as a factor that determines the economic development and well-being of the country, support to small and medium-sized businesses through the implementation of marketing principles in economic activity, effective Standards of marketing research UAM 91.12.0-2108654-001-2002 in order to promote fair competition. In combination with the global trend of network society development – Internet – marketing, digital marketing and marketing statistics are nowadays becoming a special source of intellectual resources. The problem remains the complexity of obtaining and integrating data, the volumes of which continue to grow. The purpose of this study is to substantiate the relevance of the study of marketing statistics and to seek optimization of modern methods of processing and analysis of marketing information in order to simplify the acquisition and integration of data. In the process of research such methods of scientific cognition were used: observation and abstraction, comparison, analysis and synthesis, methods of historical and logical analysis of socio-economic realities. Modern marketing statistics tools include a variety of SMM (Social Media Marketing) cases, guides, Search Engine Optimization, hashtags, UTM tags, custom auditing, analytics, and social advertising programs networks, project management, context tools. The main results of the study were the argumentation of the relevance of the study of marketing statistics and proposals for the optimization of modern methods of processing and analysis of marketing information to facilitate the acquisition and integration of data. The main ones are: 1) marketing information should be relevant, accessible and understandable to all market participants; 2) in the market conditions, higher education institutions in the respective field of training should train special specialists – highly qualified analysts with the necessary skills; 3) consumers of marketing services will not be completely satisfied until marketers are able to accompany them at all stages of the life cycle; 4) marketing statistics methods should be consolidated, systematized and optimized; 5) analytical tools should become key success factors in marketing statistics; 6) other factors for success should be establishing an effective data analysis at a particular enterprise.
Improving the Efficiency of Investment Project Selection Mechanisms at the Enterprise
Authors:   Central Ukrainian National Technical University, Nisfoian Serhii , Sysolina Nataliia ,   Central Ukrainian National Technical University, Savelenko Hryhorii ,   Central Ukrainian National Technical University
Published: October 2021

It is important for companies to choose the optimal project, considering the impact of the most important criteria on the common goal. The article investigates the mechanism of choosing the optimal of the three proposed investment projects at the production enterprise: production of foam blocks, production of paving slabs, production of concrete mix. To solve the problem of choosing the optimal project, the method of hierarchy analysis proposed by T. Saati was used. The method of analysis of hierarchies is considered to be a general theory of measurement, it is used to derive a scale from pairwise comparisons in multilevel hierarchical structures. Comparisons can be made on the basis of real or approximate values. The method is widely used in tasks related to multicriteria decision making, strategic planning, forecasting, etc. The method of hierarchy analysis allows to quantitatively and qualitatively compare alternative projects. The criteria for comparison were: the total amount of investment required for the project, product demand, expected profitability and payback period of the project. A multicriteria matrix model based on the method of hierarchy analysis is constructed. The relationship between the criteria was established and the consistency of results was assessed at all levels of the model. According to the results of the analysis, the optimal project was determined, which has the greatest value of the component of the vector of global priorities - 0.56529 (for the project involving the production of concrete mixtures). For this project, the criteria of "Demand" and "Profit" have the highest priorities of the vector of alternatives. The application of the method of analysis of hierarchies allows to reduce the amount of before the project work and numerically confirm the choice of the project.
Current Trends in the Development of Higher Education in the Globalized World Educational Space
Authors:   Ministry of Education and Science of Ukraine, Karzun Iryna , Muzychenko Anatolii ,   Central Ukrainian National Technical University
Published: October 2021

The paper is devoted to the study of current trends in the functioning and development of higher education in the context of globalization and digitalization. A comparative analysis of the positions of Ukraine and other countries in the development of higher education according to the Global Innovation Index, as well as the level of quality of training of educational institutions graduates according to the Global Competitiveness Index. The dynamics of training of applicants in higher education institutions of Ukraine is studied and the rating of the regions of Ukraine by the number of persons receiving higher education is given. The main components of improving the functioning of the higher education system of Ukraine are described, including financial support, quality of training of applicants, information support in the conditions of digitalization, etc. The ways to intensify the development of domestic higher education institutions are substantiated. In the sphere of financing, it is advisable to study and implement the best world experience in the field of diversification of funding sources, optimal use of financial resources, the introduction of transparent procedures for evaluating the performance of higher education institutions. Emphasis is placed on the need to improve the quality, accessibility and practical orientation of educational services, promote the development of information culture and skills of using of modern information and communication technologies. It is important to intensify the participation of domestic higher education institutions in international projects, grants and programs, as well as to develop cooperation between key stakeholders in improving the quality of higher education. It is necessary to form on the basis of higher education institutions powerful research centers capable to provide expert, informational and analytical services to customers.
Mechanisms for Sustainable Development of Airline Alliances
Authors:   Central Ukrainian National Technical University, Malakhovskyi Yurii , Mohamed Mohamed ,   Central Ukrainian National Technical University
Published: October 2021

The purpose of the publication is to deepen the theoretical and methodological provisions and develop scientific and practical recommendations for improving the organizational and economic mechanism of resource management of sustainable development of global alliances in the international cluster of passenger air transportation. Strategic bases of formation of the system approach to management of economic resources of participants of alliances are formulated. The list of principles for the implementation of a systematic approach to the management of economic resources of aviation enterprises (UERAP) includes integrity, structure, hierarchy, the relationship between the organizational system and the external environment, adaptability and flexibility, multifacetedness. Thus, integrity is understood as activity on increase of safety of flights (FS) on the basis of strategic management of economic resources of the enterprise which has general character, is shared by all useful within system of functioning by divisions of the enterprise. Multidimensionality reflects the complex structure of the system, which operates taking into account the peculiarities of the deployment of elemental, functional, organizational and dynamic aspects of activity. It is proposed to design systems for improving the efficiency of MERAE in the form of a set of organizational structures, specific forms and methods of management, which ensure an adequate level of FS by implementing measures for effective management of three types of resources (economic, financial and material). The thesis on the possibility of providing a flight safety management system (FSMS) by means of planning organizational measures to identify and eliminate the risks of incidents, cooperation on their prevention by all participants in the air transport system during flights, organizational support and investigation of non-standard events is substantiated. It is proposed to subordinate the FSMS to a clear sequence of organizational structures, responsibilities, guidelines, policies and procedures for managing certain elements of ERAE: personnel, technology, aircraft, information flows, motivation system, quality management. These elements are considered as part of the subsystems of a set of measures to improve the management of ERAE in order to ensure FS.