bluuebunny/crossref_metadata_2025 huggingface dataset:
Thermoeconomic Optimization of Steam Pressure of Heat Recovery Steam Generator in Combined Cycle Gas Turbine under Different Operation Strategies
Authors: Wang Zhen , Duan Liqiang
Published: August 2021

The optimization of the steam parameters of the heat recovery steam generators (HRSG) of Combined Cycle Gas Turbines (CCGT) has become one of the important means to reduce the power generation cost of combined cycle units. Based on the structural theory of thermoeconomics, a thermoeconomic optimization model for a triple pressure reheat HRSG is established. Taking the minimization of the power generation cost of the combined cycle system as the optimization objective, an optimization algorithm based on three factors and six levels of orthogonal experimental samples to determine the optimal solution for the high, intermediate and low pressure steam pressures under different gas turbine (GT) operation strategies. The variation law and influencing factors of the system power generation cost with the steam pressure level under all operation strategies are analyzed. The research results show that the system power generation cost decreases as the GT load rate increases, T4 plays a dominant role in the selection of the optimal pressure level for high pressure (HP) steam and, in order to obtain the optimum power generation cost, the IGV T3-650-F mode should be adopted to keep the T4 at a high level under different GT load rates.
A New Analytical Method for Modeling the Effect of Assembly Errors on a Motor-Gearbox System
Authors: El Yousfi Bilal , Soualhi Abdenour , Medjaher Kamal , Guillet François
Published: August 2021

The well-known gear tooth defects such as root cracks and flank spalls have been widely investigated in previous studies to model their effects on the time varying mesh stiffness (TVMS) and consequently the dynamic response of motor-gearbox systems. Nevertheless, the effect of assembly errors such as the center distance and the eccentricity has been less considered in past works. Determining the signature of these errors on the system response can help for their early detection and diagnostic to avoid overloading and failure of gears. An original geometric-based method combined with the potential energy method is proposed in this paper to accurately model the effect of these assembly errors on the TVMS of mating spur gear pairs. This is achieved by updating the line of action equation (LOA) at each meshing step using the actual coordinates of gear centers and employing a contact detection algorithm (CDA) to determine the actual contact points coordinates. An electrical model of a three-phase induction machine was then coupled with a dynamic model of a one-stage spur gear system to simulate the effect of assembly errors on the electromechanical response of the motor-gearbox system. The simulation results showed that the center distance error induces a reduction in the TVMS magnitude and the contact ratio, whereas the eccentricity error causes a double modulation of the TVMS magnitude and frequency. In addition, the results showed that assembly errors can be detected and diagnosed by analyzing the system vibration and the motor phase-current.
Potential of Slip Synchronous Wind Turbine Systems: Grid Support and Mechanical Load Mitigation
Authors: Ockhuis Dillan Kyle , Kamper Maarten
Published: August 2021

Wind power penetration into existing electrical power systems continues to experience year-on-year growth. Consequently, modern wind turbine systems (WTS) are required to comply with relevant grid codes and provide ancillary grid services to assist with overall grid stability. Adhering to these grid codes and services can cause additional mechanical loading on WTS, which can result in a reduction in service life of some of the drivetrain components, and instability if a sufficient means of damping is not present in the drivetrain. In this paper, a dynamic simulation model of a Type 1, direct grid-connected, fixed-speed (FS) slip-synchronous wind turbine system (SS-WTS) is developed to investigate its dynamic stability in response to the additional mechanical loads imparted onto it during transient events on the grid. The SS-WTS is not equipped with a power converter and, consequently, an understanding of its dynamic stability is critical to evaluate its ability to assist with grid services and maintain stability during transient grid conditions such as low-voltage ride-through (LVRT) events. An analytical transfer function model of a 1.5 MW geared direct grid-connected SS-WTS was derived and implemented in MATLAB/Simulink. It was found that the SS technology provides significant damping to the WTS drivetrain while maintaining dynamic stability during a severe LVRT event. Moreover, it was found that the degree of damping is directly proportional to the value of rated slip, and that high-speed drivetrains provide a greater degree of damping for a given value of rated slip. Furthermore, it is shown that the SS-WTS has the ability to assist with grid services such as primary frequency response, short-circuit strength, and reactive power compensation.
Portable Mobile Gait Monitor System Based on Triboelectric Nanogenerator for Monitoring Gait and Powering Electronics
Authors: Mao Yupeng , Zhu Yongsheng , Zhao Tianming , Jia Changjun , Wang Xiao , Wang Qi
Published: August 2021

A self-powered portable triboelectric nanogenerator (TENG) is used to collect biomechanical energy and monitor the human motion, which is the new development trend in portable devices. We have developed a self-powered portable triboelectric nanogenerator, which is used in human motion energy collection and monitoring mobile gait and stability capability. The materials involved are common PTFE and aluminum foil, acting as a frictional layer, which can output electrical signals based on the triboelectric effect. Moreover, 3D printing technology is used to build the optimized structure of the nanogenerator, which has significantly improved its performance. TENG is conveniently integrated with commercial sport shoes, monitoring the gait and stability of multiple human motions, being strategically placed at the immediate point of motion during the respective process. The presented equipment uses a low-frequency stabilized voltage output system to provide power for the wearable miniature electronic device, while stabilizing the voltage output, in order to effectively prevent voltage overload. The interdisciplinary research has provided more application prospects for nanogenerators regarding self-powered module device integration.
Life Cycle Assessment on Different Synthetic Routes of ZIF-8 Nanomaterials
Authors: Ntouros Vasileios , Kousis Ioannis , Papadaki Dimitra , Pisello Anna Laura , Assimakopoulos Margarita Niki
Published: August 2021

In the last twenty years, research activity around the environmental applications of metal–organic frameworks has bloomed due to their CO2 capture ability, tunable properties, porosity, and well-defined crystalline structure. Thus, hundreds of MOFs have been developed. However, the impact of their production on the environment has not been investigated as thoroughly as their potential applications. In this work, the environmental performance of various synthetic routes of MOF nanoparticles, in particular ZIF-8, is assessed through a life cycle assessment. For this purpose, five representative synthesis routes were considered, and synthesis data were obtained based on available literature. The synthesis included different solvents (de-ionized water, methanol, dimethylformamide) as well as different synthetic steps (i.e., hours of drying, stirring, precursor). The findings revealed that the main environmental weak points identified during production were: (a) the use of dimethylformamide (DMF) and methanol (MeOH) as substances impacting environmental sustainability, which accounted for more than 85% of the overall environmental impacts in those synthetic routes where they were utilized as solvents and as cleaning agents at the same time; (b) the electricity consumption, especially due to the Greek energy mix which is fossil-fuel dependent, and accounted for up to 13% of the overall environmental impacts in some synthetic routes. Nonetheless, for the optimization of the impacts provided by the energy use, suggestions are made based on the use of alternative, cleaner renewable energy sources, which (for the case of wind energy) will decrease the impacts by up to 2%.
On the Effect of CO2 on Seismic and Ultrasonic Properties: A Novel Shale Experiment
Authors: Rørheim Stian , Bhuiyan Mohammad Hossain , Bauer Andreas , Cerasi Pierre Rolf
Published: August 2021

Carbon capture and storage (CCS) by geological sequestration comprises a permeable formation (reservoir) for CO2 storage topped by an impermeable formation (caprock). Time-lapse (4D) seismic is used to map CO2 movement in the subsurface: CO2 migration into the caprock might change its properties and thus impact its integrity. Simultaneous forced-oscillation and pulse-transmission measurements are combined to quantify Young’s modulus and Poisson’s ratio as well as P- and S-wave velocity changes in the absence and in the presence of CO2 at constant seismic and ultrasonic frequencies. This combination is the laboratory proxy to 4D seismic because rock properties are monitored over time. It also improves the understanding of frequency-dependent (dispersive) properties needed for comparing in-situ and laboratory measurements. To verify our method, Draupne Shale is monitored during three consecutive fluid exposure phases. This shale appears to be resilient to CO2 exposure as its integrity is neither compromised by notable Young’s modulus and Poisson’s ratio nor P- and S-wave velocity changes. No significant changes in Young’s modulus and Poisson’s ratio seismic dispersion are observed. This absence of notable changes in rock properties is attributed to Draupne being a calcite-poor shale resilient to acidic CO2-bearing brine that may be a suitable candidate for CCS.
Real Domestic Hot Water Consumption in Residential Buildings and Its Impact on Buildings’ Energy Performance—Case Study in Poland
Authors: Ratajczak Katarzyna , Michalak Katarzyna , Narojczyk Michał , Amanowicz Łukasz
Published: August 2021

A building’s energy consumption is assessed considering the energy required for heating, cooling, lighting, and domestic hot water (DHW). Methodologies used to calculate energy certificates in European Union countries consider hot water consumption rates per person or per heated (floor) area, giving wide-ranging values (35–88 dm3/person/day). Using extreme parameters, it is possible to obtain a primary energy index that meets the legal requirements, although unrealistically large proportions of domestic hot water use relative to the total energy balance of the building may marginalize the influence of other components, such as fluctuations in heating, ventilation, or lighting. In the current work, the DHW consumption of three residential buildings was measured to verify the energy consumption for hot water preparation. Investigations were conducted based on the consumption of natural gas for DHW preparation. Experimentally obtained water consumption rates were determined per m2 of a dwelling and per person living in the building. The calculated indicators (0.85 ± 0.005 dm3/m2/day and 27.4 ± 1.4 dm3/person/day) were lower than those used for energy certifications of buildings. The experimentally obtained indicators were used in further theoretical energy assessments of six residential buildings. By adopting the designated indicators, the analyzed buildings met the legally required primary energy value (<70 kWh/m2/year) when using natural gas as a heat source. Applying more realistic DHW consumption values resulted in more accurate energy certifications.
Analysis of an IPMSM Hybrid Magnetic Equivalent Circuit
Authors: Song In-Soo , Jo Byoung-Wook , Kim Ki-Chan
Published: August 2021

The most common type of electric vehicle traction motor is the interior permanent magnet synchronous motor (IPMSM). For IPMSM designs, engineers make use of the magnetic equivalent circuit method, which is a lumped constant circuit method, and the finite element method, which is a distributed constant circuit method. The magnetic equivalent circuit method is useful for simple design through fast and intuitive parameters, but it cannot derive the distribution of the magnetic field. The finite element method can derive an accurate magnetic field distribution, but it takes a long time and is difficult to use for analysis of intuitive design parameters. In this study, the magnetic equivalent circuit method and Carter’s coefficient were combined for rotor structure design and accurate identification and analysis of circuit constants. In this paper, this design method is called the hybrid magnetic equivalent circuit method. Intuitive design parameters are derived through this hybrid magnetic equivalent circuit method. The air gap flux density distribution according to rotor shape, no-load-induced voltage, and cogging torque was analyzed and compared to results of the finite element method. The proposed method was found to achieve a short solving time and acceptably accurate results.
Synchronization Analysis of Multiple Integral Inequalities Driven by Steklov Operator
Authors: Albalawi Wedad , Khan Zareen A.
Published: August 2021

We construct a subclass of Copson’s integral inequality in this article. In order to achieve this goal, we attempt to use the Steklov operator for generalizing different inequalities of the Copson type relevant to the situations ρ>1 as well as ρ<1. We demonstrate the inequalities with the guidance of basic comparison, Holder’s inequality, and the integration by parts approach. Moreover, some new variations of Hardy’s integral inequality are also presented with the utilization of Steklov operator. We also formulate many remarks and two examples to show the novelty and authenticity of our results.
Identification of Major Loci and Candidate Genes for Anthocyanin Biosynthesis in Broccoli Using QTL-Seq
Authors: Liu Chunqing , Yao Xueqin , Li Guangqing , Huang Lei , Wu Xinyan , Xie Zhujie
Published: August 2021

Anthcyanins determine the colors of flowers, fruits, and purple vegetables and act as important health-promoting antioxidants. BT 126 represents a broccoli variety with a high content of anthocyanins (5.72 mg/g FW). Through QTL-seq bulk segregant analysis, the present study aimed to determine the quantitative trait loci (QTLs) involved in anthocyanin biosynthesis in the F2 population (n = 302), which was obtained by crossing BT 126 with a non-anthocyanin-containing SN 60. The whole-genome resequencing of purple (n = 30) and green (n = 30) bulk segregates detected ~1,117,709 single nucleotide polymorphisms (SNPs) in the B. oleracea genome. Two QTLs, tightly correlated with anthocyanin biosynthesis (p < 0.05), were detected on chromosomes 7 (BoPur7.1) and 9 (BoPur9.1). The subsequent high-resolution mapping of BoPur9.1 in the F2 population (n = 280) and F3 population (n = 580), with high-throughput genotyping of SNPs technology, narrowed the major anthocyanin biosynthesis QTL region to a physical distance of 73 kb, containing 14 genes. Among these genes, Bo9g174880, Bo9g174890, and Bo9g174900 showed high homology with AT5G07990 (gene encoding flavonoid 3′ hydroxylase), which was identified as a candidate gene for BoPur9.1. The expression of BoF3’H in BT 126 was significantly higher than that in SN60. Multiple biomarkers, related to these QTLs, represented potential targets of marker-assisted selection (MAS) foranthocyanin biosynthesis in broccoli. The present study provided genetic insights into the development of novel crop varieties with augmented health-promoting features and improved appearance.
Opportunity Cost of Environmental Regulation in China’s Industrial Sector
Authors: Wang Ye , Lu Yunguo , Zhang Lin
Published: August 2021

In this paper, we employ a directional distance function to estimate the opportunity cost arising from environmental regulations in China’s industrial sector. The change of opportunity cost is decomposed mathematically into two components including technical change and input change. Our results show that the opportunity cost attributed to environmental regulation is nil in some regions. The change of opportunity cost is marginal at the national level, as the positive effect of technical change is canceled out by the negative impact of input change on opportunity cost. Built on our mathematical decomposition, we further estimate the effects of environmental regulations on opportunity cost using a mediation model. It shows that environmental regulation has a significantly positive direct effect and a significantly negative indirect effect through foreign direct investment on opportunity cost. Our findings suggest, firstly, that inward FDI in China’s industrial sector represents relatively dirty production technology; and, secondly, industrial production has transited towards a less carbon-intensive input mix. This paper, therefore, provides new insights for the recent dynamics of carbon abatement performance of China’s industrial sector with policy implications.
The Influence of Rehabilitation on Quality of Life in Breast Cancer Survivors: A Clinical Study
Authors: Paolucci Teresa , Saggino Aristide , Agostini Francesco , Paoloni Marco , Bernetti Andrea , Mangone Massimiliano , Santilli Valter , Saggini Raoul , Tommasi Marco
Published: August 2021

Background: Breast cancer survivors report negative impacts of cancer, augmented by specific vulnerabilities to body changes, negative self-assessment, and quality-of-life concerns. The main objective of our work was to test the effect of a rehabilitation program on breast cancer patients by evaluating the change in their physical well-being during an outpatient rehabilitation setting and, subsequently, in a home rehabilitation setting, considering the individual personality profile. Methods: Patients who underwent total mastectomy with breast prostheses or tissue expanders were enrolled. Outcome assessments (Pain, Quality of Life, Personality traits for the Minnesota Multiphasic Personality Inventory-2) before treatment (T0), at the end of the rehabilitative treatment (T1 = 10 sessions 2/week, one hour/each), and after two months of follow-up (T2) were performed. Results: The data of 38 included patients were analyzed. The quadratic trend of the Visual Analogue Scale can be explained by the fact that patients have a strong reduction in the perceived pain immediately after rehabilitation in the clinic. This reduction remains constant for the home period of the rehabilitation. The personality profiles of all the participants were substantially valid. Only three patients obtained scores higher than 65 points. Conclusions: The study evidenced that in the initial phase of the rehabilitation, psychological traits such as anxiety, depression, and preoccupation could have a strong association especially with the autonomous functions and the perceived physical symptoms. However, during the therapeutic process, this association decreased and these decrements were higher when patients performed their rehabilitation at home, in a more familiar and comfortable setting.
Exploring the Leadership–Engagement Nexus: A Moderated Meta-Analysis and Review of Explaining Mechanisms
Authors: Decuypere Anouk , Schaufeli Wilmar
Published: August 2021

This study aims to review and quantify the value of several well-established positive leadership styles for employee work engagement in organizations. We perform both a quantitative and qualitative review (k = 86). Our (moderated) meta-analysis indicates that transformational, authentic, empowering, ethical, and servant leadership all share overlap in confidence and credibility intervals, and they may result in the same effect on work engagement (general r = 0.47). Additional theoretical analysis indicated a common ground within these positive leadership styles, i.e., having a moral perspective as a leader, role-modelling behaviour, follower self-determination, and positive social exchanges with employees. Based on the studies in the sample, we also build an integrative research model with several categories of mediators and moderators that have a well-established impact on work engagement. The moderator categories were follower characteristics and team- and organizational-level moderators. The mediator categories were psychological needs, trust, resources, and organizational-level variables. The combination of a meta-analysis with systematic review and research model can facilitate future research and supports practitioners to improve leadership.
Exploring Treatment for Depression in Parkinson’s Patients: A Cross-Sectional Analysis
Authors: DeMarco Elisabeth C. , Al-Hammadi Noor , Hinyard Leslie
Published: August 2021

Depression is a highly prevalent, often underrecognized and undertreated comorbidity of Parkinson’s disease closely correlated to health-related quality of life. National trends in depression care for patients with Parkinson’s disease are not well documented. This paper identifies a cohort of patients with Parkinson’s disease from nationally representative survey data and analyzes trends in depression care. Using data from the 2005–2006 through 2015–2016 waves of the National Health and Nutrition Examination Survey (NHANES), individuals were classified as Parkinson’s patients by reported medication use. PHQ-9 scores were used to identify individuals screening positive for depression. A composite treatment variable examined the reported use of mental health services and antidepressant medication. Survey participants with probable PD screened positive for depression, reported the use of antidepressant medication, and reported visits to mental health services more frequently than the control group. Survey participants with PD who screened positive for depression were more likely to report limitations in physical functioning due to an emotional problem than controls. While depression is highly prevalent among individuals with Parkinson’s disease, they are more likely to receive any treatment. Further research is required to investigate differences in patterns of treatment, contributing factors of emotions to limitations in physical functioning, and appropriate interventions.
Association between Osteoporosis and Low Hemoglobin Levels: A Nested Case–Control Study Using a National Health Screening Cohort
Authors: Kim So-Young , Yoo Dae-Myoung , Min Chanyang , Choi Hyo-Geun
Published: August 2021

An association between anemia and an increased risk of osteoporosis has been suggested. The goal of this study was to estimate the association of hemoglobin (Hb) level with osteoporosis. A total of 69,760 osteoporosis patients aged ≥ 40 years old from the Korean National Health Insurance Service Health Screening Cohort were enrolled. From an identical cohort database, 69,760 comparison participants were randomly selected. Hb levels before the onset of osteoporosis were evaluated. The association of Hb level with osteoporosis was analyzed using a conditional logistic regression model adjusted for obesity, smoking status, alcohol consumption, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, and the Charlson comorbidity index score. Fifteen percent of the osteoporosis group and 14.17% of the comparison group had anemia. The Hb level was associated with 0.98-fold lower odds for osteoporosis (95% confidence intervals = 0.97–0.99, p < 0.001). A low Hb level was associated with a high risk of osteoporosis in the adult population. There was a consistent association between a low Hb level and osteoporosis in patients with comorbidities.
Are Diverse Media Better than a Single Medium? The Relationship between Mixed Media and Perceived Effect from the Perspective of Online Psychological Counseling
Authors: Liu Jingfang , Gao Lu
Published: August 2021

The progress of new media has promoted the development of online health consultations. Previous research has investigated the impact of media richness on user satisfaction; however, little attention has been given to the mixed effects of the nesting of multiple media. The purpose of this study is to analyze the impact and differences of the use of single or mixed media on users’ perceived effect from the perspectives of social support and satisfaction by mining user reviews on online health platforms. The data were collected from a professional online psychological counseling platform. We collected data on 48,807 reviews from 11,694 users. Text annotation and sentiment analysis were then used to extract variable eigenvalues from the reviews. One-way analysis of variance (ANOVA) and hierarchical regression analysis were used for statistical analysis. The results show that mixed media with different richness has a significant impact on the users’ perceived effects. Among them, compared to “text + audio,” using “text + audio + video/face to face” can significantly improve the users’ perceived social support and satisfaction. However, compared to single medium, mixed media with higher richness may not necessarily achieve a better effect. We found that the inclusion of “video/face to face” mixed media significantly reduced the users’ perceived social support and satisfaction compared to text or audio use alone. These research results complement the blank media richness theory in the field of online health care and provide guidance for improving the personalized customization of online psychological counseling platforms.
The Impact of the COVID-19 Pandemic on Tourists’ WTP: Using the Contingent Valuation Method
Authors: Jeon Chang-Young , Yang Hee-Won
Published: August 2021

This study estimated tourists’ willingness to pay (WTP) for tourist sites or facilities in the prolonged COVID-19 pandemic by applying the dichotomous choice-contingent valuation method to two different tourism destination types. A survey was conducted among domestic tourists in South Korea who had visited destinations within the last six months. We conducted a logistic regression with 1283 effective samples. The results showed differences in tourists’ WTP, depending on type, and the factors affecting WTP differed. Tourists with higher tourism attitude and knowledge of tourism risk exhibited a higher WTP. Tourists with higher perceived risk of infectious disease exhibited less WTP.
Problem Gambling ‘Fuelled on the Fly’
Authors: Teal Joseph , Kusev Petko , Heilman Renata , Martin Rose , Passanisi Alessia , Pace Ugo
Published: August 2021

Problem gambling is a gambling disorder often described as continued gambling in the face of increasing losses. In this article, we explored problem gambling behaviour and its psychological determinants. We considered the assumption of stability in risky preferences, anticipated by both normative and descriptive theories of decision making, as well as recent evidence that risk preferences are in fact ‘constructed on the fly’ during risk elicitation. Accordingly, we argue that problem gambling is a multifaceted disorder, which is ‘fueled on the fly’ by a wide range of contextual and non-contextual influences, including individual differences in personality traits, hormonal and emotional activations. We have proposed that the experience of gambling behaviour in itself is a dynamic experience of events in time series, where gamblers anchor on the most recent event—typically a small loss or rare win. This is a highly adaptive, but erroneous, decision-making mechanism, where anchoring on the most recent event alters the psychological representations of substantial and accumulated loss in the past to a representation of negligible loss. In other words, people feel better while they gamble. We conclude that problem gambling researchers and policy makers will need to employ multifaceted and holistic approaches to understand problem gambling.
Impact of Three Waves of the COVID-19 Pandemic on the Rate of Elective Cataract Surgeries at a Tertiary Referral Center: A Polish Perspective
Authors: Dmuchowska Diana Anna , Pieklarz Barbara , Konopinska Joanna , Mariak Zofia , Obuchowska Iwona
Published: August 2021

The aim of this study was to assess the effect of three waves of the COVID-19 pandemic on the number of elective cataract surgeries. A retrospective single-center consecutive case series study was performed. We included all 12,464 patients who received cataract surgery in the period between 1 January 2016 and 31 May 2021. Monthly numbers of cataract surgeries during the pandemic were compared with monthly numbers in the reference years 2016–2019. In the pandemic the number of cataract surgeries decreased by 53.4%. The monthly numbers during the first, second and third wave of the pandemic were 77.5%, 51.5% and 29.7% lower, respectively, compared with the reference level. No rebound effect was observed once the pandemic restrictions were eased. Simultaneous bilateral cataract surgeries (SBCS) constituted 6.5% of cataract procedures performed in April and May 2021 compared with 0.77% carried out between May 2019 and March 2021. While the pandemic-affected monthly numbers of cataract surgeries tend to increase recently, they are still below the prepandemic level. Patients should be encouraged to weigh the risks of COVID-19-related morbidity and mortality against the benefits of cataract surgery. Reorganization of the logistics of cataract services is advisable with consideration of SBCS as one of the options.
Can Pets Replace Children? The Interaction Effect of Pet Attachment and Subjective Socioeconomic Status on Fertility Intention
Authors: Guo Zhen , Ren Xiaoxing , Zhao Jinzhe , Jiao Liying , Xu Yan
Published: August 2021

A growing number of young people tend to regard their pets as their surrogate children, yet research examining the relationship between pet attachment and fertility intention remains scarce. Moreover, individuals’ fertility intention is affected by economic resources. Therefore, we conducted two studies to examine the interaction effect of pet attachment and subjective socioeconomic status (SES) on childbearing-aged individuals’ fertility intention. In Study 1, we utilized questionnaires to measure Chinese pet owners’ pet attachment, subjective SES, and fertility intention. In Study 2, participants’ pet attachment was experimentally manipulated by reading articles about the benefits of petkeeping. The results of the two studies consistently demonstrated that the effect of pet attachment on fertility intention was moderated by subjective SES. Specifically, pet attachment was negatively associated with fertility intention when individuals had a high level of subjective SES, whereas this effect disappeared when individuals had low subjective SES. These findings suggest an explanation for why individuals with high subjective SES delay or even opt out of childbearing. The limitations and implications of the current study are discussed.
The Short-Term Impact of Animation on the Executive Function of Children Aged 4 to 7
Authors: Fan Liheng , Zhan Meichen , Qing Wenjing , Gao Tan , Wang Mengying
Published: August 2021

Research has shown that animation plays an important role in the development of children’s executive function (EF), and the development of EF components, inhibitory control, working memory, and cognitive flexibility, is asynchronous. Thus, this study explores the developmental trajectories and animation features (fantasy and pacing) that influence each EF component, by examining 218 children aged 4–7. Pretest information, mainly the childhood EF inventory, was provided by parents: child’s age, age of first exposure to animation, animation viewing time on weekdays and weekends, family income, and parents’ education. The children in each age group were randomly divided into four groups to watch animations comprised of different animation features. After watching, their EF were measured by a day-night task, backward digit-span task, and flexible item-selection task. The results showed that the children’s inhibitory control, working memory and cognitive flexibility levels all improved with age. Highly fantastical animations weakened children’s performance on each subsequent EF task. Pacing had no effect on any of the components of children’s EF. An interactive effect on inhibitory control was only found with fantasy in younger children; specifically, high-fantastical animations had a more pronounced short-lived weakening effect on inhibitory control in younger children (4–6 years) compared with low-fantastical animations. Future research should explore the long-term impact of content rather than the form of animation on younger children’s EF.
Occurrence of Mental Illness and Mental Health Risks among the Self-Employed: A Systematic Review
Authors: Willeke Kristina , Janson Patrick , Zink Katharina , Stupp Carolin , Kittel-Schneider Sarah , Berghöfer Anne , Ewert Thomas , King Ryan , Heuschmann Peter U. , Zapf Andreas , Wildner Manfred , Keil Thomas
Published: August 2021

We aimed to systematically identify and evaluate all studies of good quality that compared the occurrence of mental disorders in the self-employed versus employees. Adhering to the Cochrane guidelines, we conducted a systematic review and searched three major medical databases (MEDLINE, Web of Science, Embase), complemented by hand search. We included 26 (three longitudinal and 23 cross-sectional) population-based studies of good quality (using a validated quality assessment tool), with data from 3,128,877 participants in total. The longest of these studies, a Swedish national register evaluation with 25 years follow-up, showed a higher incidence of mental illness among the self-employed compared to white-collar workers, but a lower incidence compared to blue-collar workers. In the second longitudinal study from Sweden the self-employed had a lower incidence of mental illness compared to both blue- and white-collar workers over 15 years, whereas the third longitudinal study (South Korea) did not find a difference regarding the incidence of depressive symptoms over 6 years. Results from the cross-sectional studies showed associations between self-employment and poor general mental health and stress, but were inconsistent regarding other mental outcomes. Most studies from South Korea found a higher prevalence of mental disorders among the self-employed compared to employees, whereas the results of cross-sectional studies from outside Asia were less consistent. In conclusion, we found evidence from population-based studies for a link between self-employment and increased risk of mental illness. Further longitudinal studies are needed examining the potential risk for the development of mental disorders in specific subtypes of the self-employed.
The Early Stage of the COVID-19 Outbreak in Tunisia, France, and Germany: A Systematic Mapping Review of the Different National Strategies
Authors: Laffet Khouloud , Haboubi Fatma , Elkadri Noomene , Georges Nohra Rita , Rothan-Tondeur Monique
Published: August 2021

The multitude of national strategies used against the COVID-19 pandemic makes it necessary to review and synthesize them in order to identify potential gaps and shortcomings, and to help prioritize future control efforts. This systematic mapping review is aimed at identifying the coronavirus pandemic management strategies adopted by France, Tunisia, and Germany during the early stage of the COVID-19 outbreak. A set of government websites in addition to the PubMed and Google Scholar databases were searched to identify scientific articles and institutional documents related to the national strategies of the three countries up until July 2020. The references included were mapped and narratively synthesized based on the pillars of the Monitoring and Evaluation Framework of the Strategic Preparedness and Response Plan defined by the World Health Organization. Of the 2765 records screened, 65 documents were included in the study. The analysis of these documents showed that Germany was the first country to implement mass screening of cases and that France was the first country to implement measures to impose general containment at the national level. It also showed that Tunisia was the only country to have imposed the confinement of passengers on repatriation flights in dedicated containment centers and at the expense of the state.
Concentrations of Lead, Mercury, Arsenic, Cadmium, Manganese, and Aluminum in the Blood of Pakistani Children with and without Autism Spectrum Disorder and Their Associated Factors
Authors: Rahbar Mohammad H. , Ibrahim Shahnaz H. , Azam Syed Iqbal , Hessabi Manouchehr , Karim Fatima , Kim Sori , Zhang Jing , Gulzar Ali Nasreen , Loveland Katherine A.
Published: August 2021

Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with early onset in utero or childhood. Environmental exposure to six metals (Pb, Hg, As, Cd, Mn, Al) is believed to be associated with ASD directly or interactively with genes. Objective: To assess the association of ASD among Pakistani children with the six metals and genotype frequencies of three GST genes (GSTP1, GSTM1, GSTT1). Methods: We enrolled 30 ASD cases, age 2–12 years old, and 30 age- and sex-matched typically developing (TD) controls in Karachi, Pakistan. We assessed associations of ASD status with various factors using Conditional Logistic Regression models. We also used General Linear Models to assess possible interaction of blood Mn and Pb concentrations with the three GST genes in relation to ASD status. Results: The unadjusted difference between ASD and TD groups in terms of geometric mean blood Pb concentrations was marginally significant (p = 0.05), but for Al concentrations, the adjusted difference was marginally significant (p = 0.06). Conclusions: This is the first study reporting six blood metal concentrations of Pakistani children with ASD. Estimates provided for possible interactions of GST genes with Mn and Pb in relation to ASD status are valuable for designing future similar studies.
Efficiency and Productivity Change of Public Hospitals in Panama: Do Management Schemes Matter?
Authors: Cordero José M. , García-García Agustín , Lau-Cortés Enrique , Polo Cristina
Published: August 2021

In Latin American and Caribbean countries, the main concern of public health care managers has been traditionally placed on problems related to funding, payment mechanisms, and equity of access. However, more recently, there is a growing interest in improving the levels of efficiency and reducing costs in the provision of health services. In this paper we focus on measuring the technical efficiency and productivity change of public hospitals in Panama using bootstrapped Malmquist indices, which allows us to assess the statistical significance of changes in productivity, efficiency, and technology. Specifically, we are interested in comparing the performance of hospitals belonging to the two different management schemes coexisting in the country, the Social Security Fund (SSF) and the Ministry of Health (MoH). Our dataset includes data about 22 public hospitals (11 for each model) during the period between 2005 and 2015. The results showed that the productivity growth of hospitals belonging to the SSF has been much higher than that of the hospitals belonging to the Ministry of Health over the evaluated period (almost 4% compared to 1.5%, respectively). The main explanation for these divergences is the superior growth of technological change in the former hospitals, especially in the final years of the evaluated period.
A Conceptual Design of Smart Management System for Flooding Disaster
Authors: Ibrahim Thaer , Mishra Alok
Published: August 2021

Disasters pose a real threat to the lives and property of citizens; therefore, it is necessary to reduce their impact to the minimum possible. In order to achieve this goal, a framework for enhancing the current disaster management system was proposed, called the smart disaster management system. The smart aspect of this system is due to the application of the principles of information and communication technology, especially the Internet of Things. All participants and activities of the proposed system were clarified by preparing a conceptual design by using The Unified Modeling Language diagrams. This effort was made to overcome the lack of citizens’ readiness towards the use of information and communication technology as well as increase their readiness towards disasters. This study aims to develop conceptual design that can facilitate in development of smart management system for flooding disaster. This will assist in the design process of the Internet of Things systems in this regard.
3D Perspective towards the Development of a Metadata-Driven Sharing Mechanism for Heterogeneous CCTV Systems
Authors: Hong Jung-Hong , Shi Yi-Tin
Published: August 2021

The installation of closed-circuit television monitors (CCTV) has rapidly increased in number ever since the 11 September attacks. With the advantages of direct visual inspection, CCTV systems are widely used on various occasions that require instantaneous and long-term monitoring. Especially for emergency response tasks, the prompt availability of CCTV offers EOC (Emergency Operation Center) commanders much better action reference about the reported incidents. However, the heterogeneity among the CCTV systems impedes the effective and efficient use and sharing of CCTV services hosted by different stakeholders, making individual CCTV systems often operate on their own and restrict the possibility of taking the best advantages of the huge number of existing CCTV systems. This research proposes a metadata-driven approach to facilitate a cross-domain sharing mechanism for heterogeneous CCTV systems. The CCTV metadata includes a set of enriched description information based on the analysis from the aspects of Who, When, Where, What, Why and How (5W1H) for CCTV. Sharing mechanisms based on standardised CCTV metadata can then suffice the need for querying and selecting CCTV across heterogeneous systems according to the task at hand. One distinguished design is the modelling of the field of view (FOV) of CCTV from the 3D perspective. By integrating with the 3D feature-based city model data, the 3D FOV information not only provides better visualisation about the spatial coverage of the CCTV systems but also enables the 3D visibility analysis of CCTV based on individual features, such that the selection decision can be further improved with the indexing of CCTV and features. As the number and variety of CCTV systems continuously grows, the proposed mechanism has a great potential to serve as a solid collaborated foundation for integrating heterogeneous CCTV systems for applications that demand comprehensive and instantaneous understanding about the dynamically changing world, e.g., smart cities, disaster management, criminal investigation, etc.
Advances in Computational Methodologies for Classification and Sub-Cellular Locality Prediction of Non-Coding RNAs
Authors: Asim Muhammad Nabeel , Ibrahim Muhammad Ali , Imran Malik Muhammad , Dengel Andreas , Ahmed Sheraz
Published: August 2021

Apart from protein-coding Ribonucleic acids (RNAs), there exists a variety of non-coding RNAs (ncRNAs) which regulate complex cellular and molecular processes. High-throughput sequencing technologies and bioinformatics approaches have largely promoted the exploration of ncRNAs which revealed their crucial roles in gene regulation, miRNA binding, protein interactions, and splicing. Furthermore, ncRNAs are involved in the development of complicated diseases like cancer. Categorization of ncRNAs is essential to understand the mechanisms of diseases and to develop effective treatments. Sub-cellular localization information of ncRNAs demystifies diverse functionalities of ncRNAs. To date, several computational methodologies have been proposed to precisely identify the class as well as sub-cellular localization patterns of RNAs). This paper discusses different types of ncRNAs, reviews computational approaches proposed in the last 10 years to distinguish coding-RNA from ncRNA, to identify sub-types of ncRNAs such as piwi-associated RNA, micro RNA, long ncRNA, and circular RNA, and to determine sub-cellular localization of distinct ncRNAs and RNAs. Furthermore, it summarizes diverse ncRNA classification and sub-cellular localization determination datasets along with benchmark performance to aid the development and evaluation of novel computational methodologies. It identifies research gaps, heterogeneity, and challenges in the development of computational approaches for RNA sequence analysis. We consider that our expert analysis will assist Artificial Intelligence researchers with knowing state-of-the-art performance, model selection for various tasks on one platform, dominantly used sequence descriptors, neural architectures, and interpreting inter-species and intra-species performance deviation.
Cyanobacteria, Cyanotoxins, and Neurodegenerative Diseases: Dangerous Liaisons
Authors: Sini Paola , Dang Thi Bang Chau , Fais Milena , Galioto Manuela , Padedda Bachisio Mario , Lugliè Antonella , Iaccarino Ciro , Crosio Claudia
Published: August 2021

The prevalence of neurodegenerative disease (ND) is increasing, partly owing to extensions in lifespan, with a larger percentage of members living to an older age, but the ND aetiology and pathogenesis are not fully understood, and effective treatments are still lacking. Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis are generally thought to progress as a consequence of genetic susceptibility and environmental influences. Up to now, several environmental triggers have been associated with NDs, and recent studies suggest that some cyanotoxins, produced by cyanobacteria and acting through a variety of molecular mechanisms, are highly neurotoxic, although their roles in neuropathy and particularly in NDs are still controversial. In this review, we summarize the most relevant and recent evidence that points at cyanotoxins as environmental triggers in NDs development.
CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-κB Pathway
Authors: Armento Angela , Schmidt Tiziana L. , Sonntag Inga , Merle David A. , Jarboui Mohamed Ali , Kilger Ellen , Clark Simon J. , Ueffing Marius
Published: August 2021

Age-related macular degeneration (AMD), the leading cause of vision loss in the elderly, is a degenerative disease of the macula, where retinal pigment epithelium (RPE) cells are damaged in the early stages of the disease, and chronic inflammatory processes may be involved. Besides aging and lifestyle factors as drivers of AMD, a strong genetic association to AMD is found in genes of the complement system, with a single polymorphism in the complement factor H gene (CFH), accounting for the majority of AMD risk. However, the exact mechanism of CFH dysregulation confers such a great risk for AMD and its role in RPE cell homeostasis is unclear. To explore the role of endogenous CFH locally in RPE cells, we silenced CFH in human hTERT-RPE1 cells. We demonstrate that endogenously expressed CFH in RPE cells modulates inflammatory cytokine production and complement regulation, independent of external complement sources, or stressors. We show that loss of the factor H protein (FH) results in increased levels of inflammatory mediators (e.g., IL-6, IL-8, GM-CSF) and altered levels of complement proteins (e.g., C3, CFB upregulation, and C5 downregulation) that are known to play a role in AMD. Moreover, our results identify the NF-κB pathway as the major pathway involved in regulating these inflammatory and complement factors. Our findings suggest that in RPE cells, FH and the NF-κB pathway work in synergy to maintain inflammatory and complement balance, and in case either one of them is dysregulated, the RPE microenvironment changes towards a proinflammatory AMD-like phenotype.