bluuebunny/crossref_metadata_2025 huggingface dataset:
Loss, Revision, Translation: Re-Membering the Father’s Fragmented Self in Alison Bechdel’s Graphic Memoir Fun Home: A Family Tragicomic
Authors: Tison Hélène
Published: September 2015

Fun Home is a rereading of a family history characterized by false appearances, composed many years after the suicide, or accidental death, of the author’s father; as is not uncommon in memoirs, it relies heavily on archives, but the use to which they are put in this graphic novel is quite singular. This paper analyzes Alison Bechdel’s peculiar autobiographical mode through a focus on a few of the photos in Fun Home , all of which have been redrawn by the cartoonist, whose hand holding them is often also drawn, so that, far from merely testifying to the veracity of the narrated events, as the author insists, they greatly contribute to the complexity of the graphic and narrative composition, combining syntagmatic and paradigmatic gestures (montage and juxtaposition, superimposition and substitution) that endow this attempt to recover the figure of the father, and the father-daughter lineage, with a powerful poetic expressiveness.
The Monstrous Alchemy of Alan Moore: Promethea as Literacy Narrative
Authors: Howell Tracee L.
Published: September 2015

I argue that Alan Moore’s Promethea is nothing short of compositional alchemy: a radically instructive guide to the graphic medium that takes us on a revelatory exploration of the comic/graphic novel qua magical, imaged-narrative. Read as a whole, the comic series forms a primer that teaches the reader not only how to decipher a culturally-abjectified text, the comic, but by bringing traditional epistemologies into question suggests how readers consciously enact the monstrous, mystical causal dance that Scott McCloud explains is “at work in the spaces between panels.” In this essay I further propose that Promethea may be especially compelling for academic readers, since it performs as literacy narrative by telling the story of a scholar who transforms herself into story. Promethea thus forces the scholarly reader especially to become aware, often uncomfortably so, of that continual process of collaborative narrative construction, and of our own complicity, creative power, and responsibility as empowered.
Fantasies of Choosing in Rasselas
Authors: Stern Rachel Michelle
Published: September 2015

Although Samuel Johnson’s theme of “the choice of life” in Rasselas has received plentiful scholarly attention, few accounts have pursued the possibility that this idea, rather than being the premise of Johnson’s exploration of human experience, is in fact the principal object of his critique. I argue that Johnson’s treatment of “the choice of life” in Rasselas is consistent with his presentation of the other dire examples of pernicious fantasy that abound throughout his oeuvre. He presents the fantasy of an ultimate “choice” as, in fact, a mode of deferral and even as an abdication of agency.
Recent Studies in the Restoration and Eighteenth Century
Authors: O’Quinn Daniel
Published: September 2015

An assessment of recent scholarly work treating the literature of the Restoration and Eighteenth Century and some general observations on the state of the profession. A full bibliography and price list of works received by SEL for consideration follow.
Revisions and Revelations in Frances Burney’s Cecilia Manuscript
Authors: Havens Hilary
Published: September 2015

In fixating on Frances Burney’s determination not to change Cecilia ’s confrontation scene and ending, we have neglected to detect her willingness to make other changes. Unlike Evelina , which was written in secret, members of Burney’s family circle read and commented on Cecilia as a novel-in-progress. An examination of the manuscript draft held at the Berg Collection of The New York Public Library confirms the extent to which Burney amputated Cecilia . She systematically softened her most trenchant sarcasm and even suppressed a description of satanic rites, which is undeniably one of her darkest and most intriguing prose set pieces.
Madness and Matrimony in Frances Burney’s Cecilia
Authors: Jordan Meghan
Published: September 2015

Frances Burney’s novel Cecilia, or Memoirs of an Heiress (1782) provides a crucial counter to studies of the marriage plot. Burney’s novel, instead of accepting marriage as a convenient solution to the ills of a decadent, late eighteenth-century society, represents marriage as both mollifying and contributing to the oppression of women in a patriarchal society. Thus, Cecilia ’s representation of matrimony both subverts and preserves the ideological dominance of marital unions, demonstrating that the ultimate crisis therein is a crisis over women’s self-possession and self-definition.
The Sultan’s Tears in Zara , an Oriental Tragedy
Authors: Balzo Angelina Del
Published: September 2015

Oriental tragedies were among the most popular new plays of the eighteenth century and the most commonly revived. David Hume theorizes that the pleasure of tragedy comes from creating two separate presences, the character and the actor, with whom the audience could sympathize. Oriental settings paradoxically increase the potential for sympathetic exchange by highlighting the distance between the spectators and the tragic subjects. This paper focuses on Aaron Hill’s The Tragedy of Zara (1735) and argues that its metatheatrical metaphors of spectatorship increase the potential for sympathetic exchange in order to, in the words of Hill, “teach a languid people how to feel.”
Cowper’s Theatrical Blank Verse: Shakespeare, Garrick, and The Task
Authors: Hildebrand Jayne
Published: September 2015

This essay argues that Cowper’s innovative use of blank verse in The Task is indebted to the verse of Shakespeare’s plays as performed by David Garrick in the mid-eighteenth century. Cowper appropriates Garrick’s naturalistic performance as a model for the poet’s vocation, figuring the poet as a medium for divine communication just as the actor is a medium for the playwright’s art. The Task ’s many references to theater show that this unusual georgic is less concerned with cultivating nature than with cultivating the naturalistic transparency of the poet’s voice, a transparency to which the Romantics would aspire in turn.
Linguistic Instability in R. B. Sheridan’s Pizarro
Authors: Wiley Michael
Published: September 2015

Richard Brinsley Sheridan’s Pizarro (1799) demonstrates a world in geographical and linguistic play, a world of uncertain boundaries and definitions. Coming out of David Hartley’s philosophy—and out of Sheridan’s own theatrical and oratorical history—in which national and cultural experiences lead to differing associations and understandings, Sheridan’s Pizarro details an antifoundational hermeneutics of linguistic and representational instability and change.
The Wordsworthian Acoustic Imagination, Sonic Recursions, and “that dying murmur”
Authors: Speitz Michele
Published: September 2015

This essay focuses on echoes and murmurs in William Words- worth’s verse as signs of loss or rupture. Acknowledging the overlap between the unavoidably dissipating songs of humanity and the muted reminder of our ephemerality encoded within the sounds of his verse, Wordsworth foregrounds the urgent chases of quest romance as a model for the enduring auditory patterns that inform Lyrical Ballads . Once-pursued murmurs become threnodic, fragmentary echoes, recalling the extralingual threads that bind balladic romances to lyric poetry. In Wordsworth’s resulting acoustic imagination, this nonsemantic expression of disquieting affect resides beneath and within a lasting, ongoing sonic genealogy.
Coleridge, Politics, and the Theory of Life
Authors: Risinger Jacob
Published: September 2015

Samuel Taylor Coleridge’s most sustained reflection on the political implications of organic life emerged not in the radical 1790s but in his later political prose. In Theory of Life (1816), Coleridge attempted to reconcile his attraction to proto-evolutionary thinking with his own religious concerns. This careful balancing act reappeared as a central fixture in his later political thought. The discontinuities evident in the analogy he drew between political life and the “sinuous” line of evolution point toward the necessity of developing a nuanced understanding of Coleridge’s organic thought, one that avoids an oversimplified exportation of aesthetic theory into the political realm.
Finnish wood harvesting contractors’ risks in Russia
Authors: Karvinen Sari , Nummelin Tuomas
Published: September 2015

Finnish wood harvesting contractors have been working in Russia since the 1990s and new entrepreneurs are still interested in starting operations there, even though Russia is not an easy business environment. This study identifies the most significant risks in contracting in Russia. Risks were identified through expert evaluation and a risk analysis was conducted by using a risk matrix. Possible preventative measures were assessed for the identified risks. Some risks were found to be common in Russia and Finland, for example a limited number of clients, dependency on a few clients, and weak negotiating positions. A stable amount of work, i.e. the availability of stands for harvesting, was also a challenge on the both sides of border. Typical problems in Russia were breaches of contract, especially disagreements on wood measurement and payment delays, potentially causing serious economic losses. Specific to Russia were problems related to machine service and spare parts, as well as security issues. The professional skills of machine operators, as well as changing work motivation were risks in Russia. Cultural differences lead to more challenging supervision and management of staff. Among the external factors, the most challenging in Russia were unhealthy competition in the marketplace and non-transparent and the unpredictable procedures of the authorities. In Russia problems caused by seasonality are amplified by the sparse road network and longer downtime. The revealed specific features of the Russian business environment can help Finnish wood harvesting companies to plan a risk management process for operations in Russia.
NARSKCA: Novel and robust symmetric key cryptography algorithm
Authors: Maram Balajee , Kumar Y Ramesh , Rao K Lakshmana
Published: September 2015

In this research paper, a novel and strong symmetric key cryptography algorithm is proposed. NARSKCA is based on several symmetric cryptographic algorithms. NARSKCA is very simple that uses character converting algorithm, Fibonacci Number Series, Lucas Number series and bitwise XOR. In NARSKCA, 32 files are shared-secret files plays a vital role in this Proposed Algorithm. The Sub-keys are generated from those 32 shared-secret files which are useful in different rounds of Encryption and Decryption Process. The most important feature is the calculation of the final key from the Sub-Keys for each Text-Block. Key Generation, encryption/decryption schemes of NARSKCA are fast and difficult to predict by Cryptanalysts.
Enhancing woman’s role research in Turkey in terms of managerial, economical and social respects
Türkiye’de yönetsel ekonomik ve sosyal bakımdan kadın rolünü geliştirme araştırması
Authors: Kaya Ahmet , Esen Mehmet
Published: September 2015

Turkey is a big country with a population approaching 78 million. The 50.2% population of it men and 49.8% are women. According to the data 2014, Turkey is located in the category of developing countries with 10.518 dollars national income. But, young people potential and geopolitics position can not be converted to advantage for country’s economy. Because, we have to see the Netherlands which has 17 million population, has greater national income than Turkey’s which has 78 million population. This situation is undesirable status for Turkey that can not rise to the level of developed countries, unless use your advantages. However, young people are becoming aging.

In this research, Turkey’s least developed regions, Gümüşhane and its districts have been issued and the role of women’s social and economical situations are researched. For that reason, the obtained results are analyzed by statistical approaches and some inferences about that have been given.

 

Özet

Türkiye, 2014 yılı sonu itibari ile 78 milyona yaklaşan nüfusu ile büyük bir ülkedir. Nüfusun % 50.2’si Erkek, % 49.8’i kadınlardan oluşmaktadır. Bununla birlikte Türkiye, 2014 verilerine göre 10.518 dolar civarında kişi başı gelirle gelişmekte olan ekonomiler kategorisinde yer alan, jeopolitik ve genç nüfus potansiyelini avantaja dönüştürememiş ülkelerden bir tanesidir. Çünkü 78 milyon nüfusa sahip Türkiye’nin milli geliri, 17 milyonun altında nüfusa sahip Hollanda’nın gerisinde olduğunu görmek gerekir. Bu güne kadar Türkiye’nin Genç nüfus avantajının kaybolmakta olduğu, nüfusun yaşlanmaya başladığı ulaşılan diğer bir sonuçtur.

Bu araştırmada Türkiye’nin az gelişmiş bölgelerinden biri olan Gümüşhane ili ve seçilen ilçelerinde yapılan, kadının sosyal ve ekonomik yaşamdaki rolünün geliştirilmesi araştırmasında elde elde edilen sonuçlar, istatistiksel yöntemlerle analiz edilerek bir genel çıkarsama yapılması amaçlanmaktadır.
Primeira ocorrência de zirconolita na Província Alcalina do Sul do da Bahia: intrusão sienítica do Complexo Alcalino Floresta Azul, Bahia, NE Brasil
Authors: Santos Jailson Júnior Alves , Pimenta Adjanine Carvalho Santos , Rosa Maria Lourdes Silva , Conceição Herbet
Published: September 2015

Cristais de zirconolita (CaZrTi2O7) anédricos e subédricos, e com tamanhos inferiores a 20 μm foram identificados pela primeira vez na Província Alcalina do Sul do Estado da Bahia em sienitos do Complexo Alcalino Floresta Azul. Nesse estudo utilizou-se um microscópio eletrônico de varredura com detectores de elétrons secundários, elétrons retroespalhados e espectrômetro de energia dispersiva. A zirconolita é magmática e ocorre inclusa em oligoclásio antipertítico e microclina pertítica, estando usualmente em associação com baddeleíta, thorianita, zircão, monazita, esfalerita, pirita e ilmenita. Os dados químicos obtidos para os cristais de zirconolita estudados revelaram que eles são homogêneos e suas composições semelhantes àquelas descritas na literatura para zirconolitas de foid-sienitos e carbonatitos.
O Programa Institucional de Bolsa de Iniciação à Docência de Química (PIBID): reflexões para a formação docente
Authors: Barbosa Gisele Letícia dos Santos , De Souza Josefina Aparecida , Suart Rita De Cássia
Published: September 2015

O PIBID é um programa que visa a formação inicial de professores. Suas ações vêm se consolidando desde que foi implantado, em 2008, e é realidade em várias instituições de ensino superior no Brasil. Tendo em vista a relevância desse programa em âmbito nacional, analisa-se nesse trabalho a motivação dos estudantes da Licenciatura em Química de uma Universidade do sul de Minas Gerais ao ingressarem nesse programa, bem como, as expectativas dos professores em formação inicial com relação à contribuição desse programa para a formação docente. Foram realizadas entrevistas semi-estruturadas com doze participantes do PIBID/Química durante o segundo período letivo do ano de 2013. Os resultados mostram que, embora alguns licenciandos tenham iniciado o curso sem compreenderem o verdadeiro papel da docência, a participação no PIBID parece estar contribuindo para uma imersão dos futuros professores na prática profissional, bem como, aumentando o interesse deles em seguirem a carreira docente.
“The language is race and patriotism”: New schools and new Sino-Peruvian press in Peru ——The debate on education of Chinese and Mixed-blood 1931–2015
Authors: Lausent-Herrera Isabelle
Published: September 2015

Attempts to establish a college allowing the children of the Chinese community in Peru to learn and speak Chinese and be raised according to the Chinese cultural traditions began in 1886 (Lausent-Herrera 2015). These attempts coming from Chinese institutions as Beneficencia China (Chinese Benevolent Association) as well as the Catholic Church had relatively little success. Travelling to China and private tuition were for a long time the only ways to preserve the Chinese identity and the use of the language. In the 1920s the community became wealthier and politicized, the education issue was at the center of social life and became the subject of a political debate. It felt urgent to take control of the Chinese and mixed-blood youth by creating colleges that would be devoted to them.

At the same time, awakened by the seriousness of the political situation in China and by the increase of anti-Asiatic sentiment in Peru, the Sino-Peruvian community realized that its future was at stake. The schools were founded while the most politicized of the Chinese and Tusan (Tusheng)

Tusan or Tusheng are children born in Peru from Chinese parents and soon/daughter of a Chinese father and a Peruvian mother (see Lausent-Herrera 2009).

intellectuals tried to impose their ideas on education and on the future of the society in general. Two new magazines

A third magazine was created during this period, La Voz del Oriente, founded in 1933 by Jaime Pun and Guillermo de Brito (MRE, 1/1/1933, arch. 91, 3ra gaveta). The first issues of this magazine, focused mainly on the commercial activities of the Chinese community, cannot be found. We do not know, therefore if they took part in the debates at that time.

animated the debate: Oriental and New Chung Wa, and three schools, El Centro de Cultura, the Chung Wha, called the Colegio Chino of the Beneficencia and the San Min, known as the Progreso, an emanation of the Guomindang, were at the centre of the controversy which would affect the future of the Chinese community in Peru.
DREADD-Induced Silencing of the Medial Olfactory Tubercle Disrupts the Preference of Female Mice for Opposite-Sex Chemosignals
Authors: DiBenedictis Brett T. , Olugbemi Adaeze O. , Baum Michael J. , Cherry James A.
Published: September 2015

Attraction to opposite-sex pheromones during rodent courtship involves a pathway that includes inputs to the medial amygdala (Me) from the main and accessory olfactory bulbs, and projections from the Me to nuclei in the medial hypothalamus that control reproduction. However, the consideration of circuitry that attributes hedonic properties to opposite-sex odors has been lacking. The medial olfactory tubercle (mOT) has been implicated in the reinforcing effects of natural stimuli and drugs of abuse. We performed a tract-tracing study wherein estrous female mice that had received injections of the retrograde tracer, cholera toxin B, into the mOT were exposed to volatile odors from soiled bedding. Both the anterior Me and ventral tegmental area sent direct projections to the mOT, of which a significant subset was selectively activated (expressed Fos protein) by testes-intact male (but not female) volatile odors from soiled bedding. Next, the inhibitory DREADD (designer receptors exclusively activated by designer drugs) receptor hM4Di was bilaterally expressed in the mOT of female mice. Urinary preferences were then assessed after intraperitoneal injection of either saline or clozapine-N-oxide (CNO), which binds to the hM4Di receptor to hyperpolarize infected neurons. After receiving CNO, estrous females lost their preference for male over female urinary odors, whereas the ability to discriminate these odors remained intact. Male odor preference returned after vehicle treatment in counterbalanced tests. There were no deficits in locomotor activity or preference for food odors when subject mice received CNO injections prior to testing. The mOT appears to be a critical segment in the pheromone–reward pathway of female mice.
UNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons
Authors: Edwards Stacey L , Morrison Logan M , Yorks Rosalina M , Hoover Christopher M , Boominathan Soorajnath , Miller Kenneth G
Published: September 2015

The conserved protein UNC-16 (JIP3) inhibits the active transport of some cell soma organelles, such as lysosomes, early endosomes, and Golgi, to the synaptic region of axons. However, little is known about UNC-16’s organelle transport regulatory function, which is distinct from its Kinesin-1 adaptor function. We used an unc-16 suppressor screen in Caenorhabditis elegans to discover that UNC-16 acts through CDK-5 (Cdk5) and two conserved synapse assembly proteins: SAD-1 (SAD-A Kinase), and SYD-2 (Liprin-α). Genetic analysis of all combinations of double and triple mutants in unc-16(+) and unc-16(−) backgrounds showed that the three proteins (CDK-5, SAD-1, and SYD-2) are all part of the same organelle transport regulatory system, which we named the CSS system based on its founder proteins. Further genetic analysis revealed roles for SYD-1 (another synapse assembly protein) and STRADα (a SAD-1-interacting protein) in the CSS system. In an unc-16(−) background, loss of the CSS system improved the sluggish locomotion of unc-16 mutants, inhibited axonal lysosome accumulation, and led to the dynein-dependent accumulation of lysosomes in dendrites. Time-lapse imaging of lysosomes in CSS system mutants in unc-16(+) and unc-16(−) backgrounds revealed active transport defects consistent with the steady-state distributions of lysosomes. UNC-16 also uses the CSS system to regulate the distribution of early endosomes in neurons and, to a lesser extent, Golgi. The data reveal a new and unprecedented role for synapse assembly proteins, acting as part of the newly defined CSS system, in mediating UNC-16’s organelle transport regulatory function.
Field Application of Glyphosate Induces Molecular Changes Affecting Vegetative Growth Processes in Leafy Spurge (Euphorbia esula)
Authors: Doğramacı Münevver , Gramig Greta G. , Anderson James V. , Chao Wun S. , Foley Michael E.
Published: September 2015

Recommended rates of glyphosate for noncultivated areas destroy the aboveground shoots of the perennial plant leafy spurge. However, such applications cause little or no damage to underground adventitious buds (UABs), and thus the plant readily regenerates vegetatively. High concentrations of glyphosate, applied under controlled environmental conditions, have been shown to cause sublethal effects in UABs of leafy spurge that produce stunted and bushy phenotypes in subsequent generations of shoots. We treated leafy spurge plants in the field with glyphosate (0, 1.1, 3.4, or 6.7 kg ai ha−1) to determine its effects on vegetative growth from UABs and on molecular processes. The number of shoots derived from UABs of glyphosate-treated plants was significantly increased compared to controls in subsequent years after application, and new shoots displayed various phenotypical changes, such as stunted and bushy phenotypes. Quantifying the abundance of a selected set of transcripts in UABs of nontreated vs. treated plants (0 vs. 6.7 kg ha−1) indicated that glyphosate impacted molecular processes involved in biosynthesis or signaling of tryptophan or auxin (ARF4,CYP79B2,PIN3,TAA1,TRP6,YUC4), gibberellic acid (GA1/CPS1,GA2/KS), ethylene (ACO1,ACS10), cytokinins (AHP1,AK2,CKX1), and the cell cycle (CDC2A,CDC2B,CYCD3;1). Glyphosate-induced effects on vegetative growth and transcript abundance were persistent for at least 2 yr after treatment. Determining the molecular mechanisms associated with vegetative reproduction in leafy spurge following foliar glyphosate-treatment could identify limiting factors or new targets for manipulation of plant growth and development in perennial weeds.
Early-Season Palmer Amaranth and Waterhemp Control from Preemergence Programs Utilizing 4-Hydroxyphenylpyruvate Dioxygenase–Inhibiting and Auxinic Herbicides in Soybean
Authors: Meyer Christopher J. , Norsworthy Jason K. , Young Bryan G. , Steckel Lawrence E. , Bradley Kevin W. , Johnson William G. , Loux Mark M. , Davis Vince M. , Kruger Greg R. , Bararpour Mohammad T. , Ikley Joseph T. , Spaunhorst Douglas J. , Butts Thomas R.
Published: September 2015

Palmer amaranth and waterhemp have become increasingly troublesome weeds throughout the United States. Both species are highly adaptable and emerge continuously throughout the summer months, presenting the need for a residual PRE application in soybean. To improve season-long control ofAmaranthusspp., 19 PRE treatments were evaluated on glyphosate-resistant Palmer amaranth in 2013 and 2014 at locations in Arkansas, Indiana, Nebraska, Illinois, and Tennessee; and on glyphosate-resistant waterhemp at locations in Illinois, Missouri, and Nebraska. The twoAmaranthusspecies were analyzed separately; data for each species were pooled across site-years, and site-year was included as a random variable in the analyses. The dissipation of weed control throughout the course of the experiments was compared among treatments with the use of regression analysis where percent weed control was described as a function of time (the number of weeks after treatment [WAT]). At the mean (i.e., average) WAT (4.3 and 3.2 WAT for Palmer amaranth and waterhemp, respectively) isoxaflutole +S-metolachlor + metribuzin had the highest predicted control of Palmer amaranth (98%) and waterhemp (99%). Isoxaflutole +S-metolachlor + metribuzin,S-metolachlor + mesotrione, and flumioxazin + pyroxasulfone had a predicted control ≥ 97% and similar model parameter estimates, indicating control declined at similar rates for these treatments. Dicamba and 2,4-D provided some, short-lived residual control ofAmaranthusspp. When dicamba was added to metribuzin orS-metolachlor, control increased compared to dicamba alone. Flumioxazin + pyroxasulfone, a currently labeled PRE, performed similarly to treatments containing isoxaflutole or mesotrione. Additional sites of action will provide soybean growers more opportunities to control these weeds and reduce the potential for herbicide resistance.
Genetic and biochemical mechanisms of involvement of antioxidant defense enzymes in the development of bronchial asthma
Authors: Polonikov A.V. , Ivanov V.P. , Bogomazov A.D. , Solodilova M.A.
Published: September 2015

In the present review we have analyzed and summarized recent literature data on genetic and biochemical mechanisms responsible for involvement of antioxidant defense enzymes in the etiology and pathogenesis of bronchial asthma. It has been shown that the mechanisms of asthma development are linked with genetically determined abnormalities in the functioning of antioxidant defense enzymes. These alterations are accompanied by a systemic imbalance between oxidative and anti-oxidative reactions with the shift of the redox state toward increased free radical production and oxidative stress, a key element in the pathogenesis of bronchial asthma
Nitric oxide and electrogenic metals (Ca, Na, K) in epidermal cells
Authors: Petukhov V.I. , Baumane L.K. , Dmitriev E.V. , Vanin A.F.
Published: September 2015

Using atomic emission spectrometry and EPR analysis metal-ligand homeostasis (MLH) has been studied in epidermal cells of 954 liquidators of the Chernobyl accident and 947 healthy individuals. A possible association of the redox status with the quantitative changes in the MLH, which could be used as discriminators of oxidative/nitrosative stress, attracts special interest. Characteristic features of oxidative stress mainly related to electrogenic metals (Ca, K, Na), were found not only among the liquidators examined, but also in some healthy individuals (18.1%); this suggests the presence of oxidative/nitrosative stress of non-radiation origin. Correlation between intracellular production of nitric oxide (NO) with quantitative changes in the electrogenic metals may indicate the possible involvement of NO in the generation of an electric potential of the cell
Oxidative stress in platelets at an oncopathology
Authors: Gorozhanskaya E.G. , Sviridova S.P. , Baykova V.N. , Zubrikhina G.N. , Dobrovolskaya M.M. , Sitov A.V.
Published: September 2015

To determine the biochemical disorders in the blood coagulation mechanism associated with oxidative stress parameters of the antioxidant status were examined in platelets of 57 colorectal cancer patients, (including 21 patients before and after surgery), and 40 healthy individuals. We determined the total content of nitric oxide (NOx), levels of superoxide dismutase (Cu/ZnSOD), glutathione and malondialdehyde (MDA). Before treatment, we observed the changes in the antioxidant defense system of platelets, which did not depend on the prevalence of malignancy: elevated levels of SOD by 16% (p<0.05), reduced glutathione and MDA in 5.2 and 1.7 times, respectively. NOx levels did not differ from the norm. Significant shifts were found in the postoperative period: they consisted of the increase in the generation of NOx both on the third, and on the 10-th day after surgery. These changes reflect apparently platelet response to the inflammatory process associated with the surgical trauma and confirm the role of NOx as a mediator of inflammation. The content of SOD after surgery was significantly reduced, but return to a baseline on the 10-th day. Despite the significant increase in the number of platelets, no correlations of the studied parameters and their aggregation ability were found.The findings suggest that metabolic disorders in vascular-platelet hemostasis are associated with oxidative stress, which provides a basis for further study of the relationship of cancer to thrombosis
Characteristics of snake envenomation in eastern India, a study of epidemiology, complications and interventions
Authors: Mukherjee Sudeb
Published: September 2015

Background: Snake bite is an important public health problem in the tropics. The annual mortality rate in India is 15000-20000 due to snake envenomation. This study intended to analyze the characteristics of snake envenomation in detail in current time.

Methods: Total 122 cases of snake bite with features of envenomation who were admitted in our hospital in last 2 years were evaluated with detailed analysis.

Results: Significant association (p<0.05) (p=0.0029 at the degree of freedom 1) was found between time of AVS administration and development of ARF and/or RP. Patients receiving AVS at or after 6 hours were more likely to develop acute renal failure (ARF) and respiratory paralysis (RP) compared to patients receiving AVS before 6 hours.  
Conclusions: Timely detection and early intervention by AVS can prevent dangerous complications and mortality of snake bites.
Efficacy of Kalo Jeera seeds (Nigella sativa) and Thankuni (Centella asiatica) supplementation on the growth performance of broiler chicken
Authors: Sarkar Chandan Kumar , Mostofa Mahbub , Sikder Md. Mahmudul Hasan , Ansari Wahedul Karim , Ahamed Md. Mostakin , Parvej Md. Shafiullah , Hasan Muhammad Rakibul
Published: September 2015

Background: In modern era, treatment methods become diversified and developed day by day and organic medicine is one of the modern technology which also introduced in our poultry sector. This experiment was conducted to evaluate the efficacy of Thankuni (Centella asiatica) and Kalo Jeera (Nigella sativa) powdered supplementation as a growth promoter in broiler chickens.

Methods: A total of 20 day-old Cobb 500 broiler chicks were randomly divided into two groups, A and B after seven days of acclimatization. The group A was kept as control and fed on only normal balanced diet. The group B was treatment group fed on normal diet with additional supplementation of Thankuni and Kalo Jeera powder in water. For observation of growth rate, live body weight was taken at first day and every seven days interval up to 5th weeks. Besides it hematological tests were performed at 35th days for searching hematological changes in both groups.  

Results: The initial body weight of groups A and Bon 1st day of this experiment were 43.00 ± 0.56 gm and 42.50 ± 0.35 gm, respectively and after 35th day of experiment final body weight were 1450 ± 57.35 gm and 1700 ± 58.56 gm (p<1%) respectively. The growth rate of treatment group B was 17.24% more (p<1%) than that of control birds. Although the dressing percentage of both group was equal but relative weight of heart, liver, spleen and pancreas were significantly higher (p<0.1) in treatment group indicates better flock health. Feed Conversion Ratio (FCR) were 1.88 in treated birds and 2.28 in control birds was the sign of economy rate of production and were analyzed and found that net profit per broiler was Tk. 10.50 (0.12 USD) and Tk. 33.00 (0.4 USD), respectively. General blood parameters of treatment group were non-significantly higher than control group.  
Conclusions: The results suggest that better growth performance were achieved in broilers supplemented with Thankuni leaf and Kalo Jeera. Both of these two herbal medicines have antimicrobial, immunostimulatory, anti-stress, fungi static, insecticidal and liver tonic properties so that there were no mortality rate. Now it can be said that uses of Thankuni and Kalo Jeera has beneficiary effects in broiler production.
Analyzing the large number problem and Newton’s G via a relativistic quantum loop model of the electron
Authors: Oakley William Sydney
Published: September 2015

The long standing problem of large numbers ~ 1044 in physics is addressed by analyzing a conceptual electron model whereby a single photon propagates adjacent to a closed space-time metric of toroidal geometry. The quantum loop based model generates the major particle characteristics: a magnetic dipole, a radial electric field, and a gravitational effect consistent with the electron rest mass. The large number value obtained by this analysis closely matches that from empirical data and clarifies the nature of Newton’s constant, GN. The particle concept provides a basis from which development of a detailed electron model should be possible.
A precancerous saree lesion: a rare occurrence
Authors: Tiwari Saurabh Jitendra , Yadgire Atul , Umale Narayan P.
Published: September 2015

Skin cancers are relatively uncommon malignancies; their incidence in India being less than 1% of all cancers. The incidence of malignancy in scar tissues is 0.1-2.5%. Squamous cell carcinoma of skin is second most common amelanotic malignancy next to basal cell carcinoma. The occurrence of this disease is noticed in various parts of the body but waist line skin is not a common site. Saree is a type of female costume and dhoti is a male costume which is unique to the Indian subcontinent. The persistent and long term wearing of this costume results in depigmentation and glazing of the skin, acanthosis, dysplasia, scar and ulceration and subsequent, but very slow, malignant changes. The exact mechanism of the malignant transformation is unknown, but recurrent trauma over a long period with consequent interference with the healing process is a possible explanation. We are presenting a rare case of left flank ulcero-proliferative growth in a 75 year old woman. Wide excision with primary skin closure was done. Histopathology showed pseudoepitheliomatous hyperplasia with marked dysplasia without microinvasion. It is a premalignant lesion. The case needs its reporting due to its rarity. Awareness of saree cancer among Indians is important to prevent malignant lesions at waistline. Multimodality management with surgery, chemotherapy and radiotherapy is ideal for good outcome.
Dyke-Davidoff-Masson syndrome: a rare cause of refractory epilepsy with cerebral infarction
Authors: Mukherjee Sudeb
Published: September 2015

Refractory epilepsy is not very uncommon in recent time. Dyke-Davidoff-Mason syndrome is one of the rare causes of refractory epilepsy. Here is a report of this rare case we have come across during treatment of refractory epilepsy in a 30 year old man.
Acute colonic pseudo-obstruction: Ogilvie syndrome
Authors: Khadda Sandeep , Yadav Ajay Kumar , Ali Anwar , Sakhrani Jitender Kumar
Published: September 2015

Colonic pseudo-obstruction (Ogilvie’s syndrome) is a functional disorder in which the colon becomes massively dilated in the absence of mechanical obstruction. Pseudoobstruction most commonly occurs in hospitalized patients and is associated with the use of narcotics, bed rest, and comorbid disease. Pseudoobstruction is thought to result from autonomic dysfunction and severe adynamic ileus. The diagnosis is made based on the presence of massive dilatation of the colon (usually predominantly the right and transverse colon) in the absence of a mechanical obstruction.
PERFORMA (PAPER TEST KIT FORMALIN) AS THE ALTERNATIVE SELECTION TO IMPROVE THE QUALITY OF FOOD INGREDIENTS
Authors: Anggraini Citra Dewi , Susiana S , Sari Putri Yurida , Anggriawan Randi Dwi , Firdaus Muhamad
Published: September 2015

Research on "PERFORMA" or Paper Test Kits Formalin is as an alternative to improve the quality of food selection. It is aiming to get a paper test kit that can detect formaldehyde contented in foodstuffs practically, fast, easy, and inexpensive. The method used in this study is an experimental method which is part of a quantitative method that aims to manipulate and control variables. The data collection is based on the research and the observation of the color change on the paper test kit is generated from Schiff reagent test, in which the paper test kit will give a purple color response when tested on foodstuffs containing formalin. Based on the analysis of variety of data, it is obtained and expressed as mean ± standard deviation with confidence interval in this study are stated at α 5%. Thus, this research paper expects that formalin test kit can be easily applied and used by the community at large. Keywords: foodstuff, formalin, paper test kits, reagents Schiff
DESIGN OF MICRO-CAPSUL GELATIN-ACACIA COACERVATION DISPERSED IN SEAWATER
Authors: Komari K
Published: September 2015

One of the prawn rearing method had been using artificial feed of gelatin-acacia microcapsule. Characteristics of this microcapsule is very small and its size can be predicted and its density is as same as sea water.This study aimed to measure size distribution of fish oil droplet and the gelatin-acacia membrane was calculated in order to get the same density of sea water. Results of this study showed that design of microcapsules were effected by density of fish oil, membrane (coacervation of gelatin – acacia), droplet size, and density of sea water. The size distribution of fish oil droplet was presented and their variation of expected size and its actual size of microcapsule can be predicted for efficiency of the encapsulation process. Keywords: design of microencapsulation, density, droplet size
THE USE OF VACUUM IMPREGNATION TECHNOLOGY TO IMPROVE SMOKING PROCESS
Authors: Sari Rodiah Nurbaya , Iah L. Ayudiarti Diah L , Gunawan G
Published: September 2015

One of the new technologies contributing to preserve of the original properties of food (as fruit or vegetables or fish) is vacuum impregnation. Vacuum impregnation is one method to preserve foods using vacuum and pressure to fill the porous with osmotic solution. The application of vacuum impregnation had been conducted on smoked processing using liquid smoke for catfish fillet (Pangasius sp) and tilapia fillet (Oreochomis sp). Vacuum impregnation tool was used having 5 kg capacity of fillet product, vacuum pressure at 0.71 kg/cm2 and range of 0-6 kg/cm2 impregnation pressure. The research had done using osmotic solution with liquid smoke 1.5% and 17.4 g of salt/liter of water and the tool was set at condition of 0.71 kg/cm2 vacuum pressure and variations treatment such of vacuum process time (5 and 10 min), impregnation pressure (1 and 2 kg/cm2), and impregnation process time (5, 15, and 25 min). Each treatment was done in two replications. Analysis of these fillets before smoking process such of water content, protein content, fat content, color measurement, and hardness (cutting force). After smoking process these fillets are also analyzed for phenols content. Results showed that based on several parameters of the treatment, smoked fillet of catfish needed 35 minutes with phenol content 0.34 mg/kg and tilapia 25 minutes with 16.40 mg/kg phenol content. Thus by using vacuum impregnation tool could be shortening the smoking process for both of fillet. Keywords: fillet, liquid smoke, original properties, vacuum impregnation
CARRAGEENAN AS BINDER IN THE FRUIT LEATHER PRODUCTION
Authors: Fransiska Dina , Nurbaity Kartika Apriani Siti , Murdinah M , Melanie Susiana
Published: September 2015

Research on the production of mango fruit leather with the addition of carrageenan as the binder has been conducted. The fruit leather production process needs ripe and fresh mango. Carrageenan which was used as the binder was produced from the extraction of seaweed Eucheuma cottonii. The concentrations of carrageenan that used were 0%, 0,2%, 0,4% and 0,6% by using gelatin as a comparison. The fruit leather ingredients are puree mango, sugar, sorbitol, and carrageenan. The analysis was conducted to the carrageenan as the binder and the fruit leather as a product. The parameters which were analyzed were moisture content, ash content, acid insoluble ash content and gel strength. The mango fruit leather was analized in terms of moisture content, water activity (Aw), organoleptic hedonic test and hedonic quality. The result showed that carrageenan had a fairly high strength gel 1322 g /cm2. Based on the result of the organoleptic test, the panelist prefer fruit leather made from puree mango with formula of puree mango : carrageenan : sorbitol is 90% : 0.2% : 9.8%. Mango fruit leather was designed in the form of thin elastic sheet with moisture content 24.39% dan Aw 0,62. Keywords: Carrageenan, fruit leather, mango, binder
APLICATION OF ATUNG (Parinarium glaberimum, HASSK) IN HANDLING OF FRESH PELAGIC FISH
Authors: Moniharapon Trijunianto , Moniharapon Angcivioletta
Published: September 2015

Atung plant (Parinarium glaberimum, HASSK) is endemic in Mollucas. Fruit of Atung have been used for hundred of years by the local fishermen when they go fishing. Efforts to preserved fresh food (especially fish) were continually pursue by using natural preserver which contained bioactive compound as antibacteria. The aim of the study was to get information on the quality (organoleptic, chemical, and microbiological) of post harvested using fish kept in atung powder and atung solution. Three kind of pelagic fish were used, namely; Layang (Decapterus sp), Tongkol (Euthynus sp) and Kembung (Restligger sp). The fishes were kept in 0,3% powder atung (W/W) and 20% atung solution (V/V), with shelf-life of freshness of 0, 4, 8, 12, 16, and 20 hours. Sensory quality test was conducted by using descriptive test with scale ranged from 1 - 9. Quality parameter observed were the appearance, odor, texture, TVB (total volatile base), pH and TPC (total plate count). The results showed that quality of post harvested fresh fish kept in atung was the best treatment and with longer shelf life of freshness; i.e. 21 hours (20 th hour) (Kembung and Tongkol), while layang fish was 17 hours (16 th hour). In other hand, the treatment without atung (control) was 9 hours (8 th hour). Atung fruits were more practical, efficient than the treatment without atung, to be used as an alternative preservative by the sea-boarding fishermen. Keywords : endemic, atung, shelf-life, fresh of pelagic fish.
STUDY OF COLLOIDAL CHITIN HYDROLYSIS TO PRODUCE THE N ACETYL GLUCOSAMINE FROM SHRIMP SHELL WASTE USING HYDROCHLORIC ACID AND NITRIC ACID
Authors: Wahyuni Sri
Published: September 2015

Shrimp processing industries produces shrimp waste by 30-75% is wasted without being processed causing environmental pollution. The purpose of this study examines efforts to produce monomers of chitin hydrolysis of colloidal chitin compound derived from shrimp shells are chemically (hydrochloric acid and nitric acid) to produce N acetyl glucosamine bioactive compounds that have health benefits. The method used in this study is the optimization of chemical hydrolysis conditions using a solution of HCl and HNO3. On determining the optimum time to sample variation colloidal chitin 0,5%, 1% and 2%, the sample is heated with time variation 1,3,6, 9,12, and 24 hours at a temperature of 60 oC and the concentration of acid was 4 M. In the determination of the optimum temperature, each sample was heated at a temperature variation of 40, 60, and 80 oC at the optimum time (9 hours ) and acid concentration of 4 M. In the determination of the optimum concentration of acid, each sample was heated at a temperature and the optimum reaction time. Production results showed the highest compound N acetyl glucosamine as 623.3 ppm, using hydrochloric acid hydrolysis reaches optimum temperature 40° C, the optimum reaction time 9 hours, the optimum concentration of 4 M hydrochloric acid, the concentration of 2% colloidal chitin. Production of N acetyl glucosamine supreme as 625.83 ppm, using nitric acid hydrolysis reaches optimum temperature 60° C, the optimum reaction time 9 hours, the optimum concentration of 4M nitric acid, and the concentration of 1% colloidal chitin. Therefore we can conclude the results of 1% colloidal chitin hydrolysis using nitric acid more efficiently produce N acetyl glucosamine than hydrochloric acid, due to the temperature, reaction time, and acid concentration are not the same ability to hydrolyze colloidal chitin. Differences in the results of hydrolysis reached 11,59 ppm. Keywords : Chitin, N acetyl glucosamine, acid hydrolysis, optimum reaction
ANTICANCER AND ANTIAGGREGATION OF SEAWEED EXTRACT
Authors: Lamid Astuti , Komari K
Published: September 2015

Exploration of seaweed potential as sources of bioactive compounts were studied and found two type seaweeds from in Bali such as Caulerpa rasemosa and Gracillaria sp had potential as food suplements and prepared and consumed as food. These seaweeds were used as vegetables in daily diet as side dishes or can be consumed alone. Their bioactive components of these seaweeds were explored for degenerative diseases. Gracillaria sp or bukung hijau were extracted with different solvents and tested qualitatively for possible bioactive component. as anti cancer agents and anti platelet aggregations were performed in vitro. Using cancer cell of mice (C3H) and New Zealang Rabbits Platelet. The results showed that anti cancer growth of the extract was 7th fraction of the extract with 78% activities and LD50 was 0.1 ppm. The anti platelets aggregation optimum of the extract was 13.2%. The formulation of food supplement from these seaweed may benefit to produce functional food related to health. Keywords: seaweed extract, anti-cancer, anti platelet aggregation