bluuebunny/crossref_metadata_2025 huggingface dataset:
Functional Seizures and Chronic Pain: A Narrative Review of common Pathomechanisms and Clinical Implications
Authors: Kannan Siddarth , Patel Kajal , Basilio Daniela Di , Kirkby Antonia , Sivan Manoj , Jones Anthony , Mohanraj Rajiv , Das Abhijit
Published: March 2024

Background
Functional seizures (FS) manifest as episodic events, bearing superficial similarities to epileptic seizures and represent a major component of Functional Neurological Disorder (FND). FS frequently present with the co-morbidity of chronic pain and the pronounced clinical and epidemiological associations between these conditions suggest potential shared pathomechanisms. Although conventional neuroimaging and neurophysiological assessments do not detect abnormalities in either condition, advanced biophysical signal analyses offer potential biomarkers.
Method
We undertook comprehensive literature review encompassing studies employing EEG, MEG, functional MRI, PET, and SPECT in FS and chronic pain. Due to the heterogenous nature of the collected data, the results of data extraction and analysis are presented in the form of a narrative synthesis.
Results
Despite some limitations, altered neural network dynamics are evident in both FS and chronic pain, revealing intriguing common mechanisms. Both conditions exhibit overactivation in sensorimotor networks and alterations in the Default Mode Network (DMN), impacting self-awareness and pain perception. Emotional processing regions, like the anterior cingulate cortex and insula, were affected in both conditions. Furthermore, Thalamocortical dysrhythmia(TCD) offers an intriguing link, influencing pain perception and seizure-like activities. Finally, suppressed alpha oscillations, linked to sensory perception, are prevalent in both conditions.
Conclusion
We identified shared neural mechanisms and a possible novel explanation (TCD) for co-occurrence of FS and chronic pain. These necessitate further exploration in subsequent studies incorporating patients exhibiting both disorders concurrently. Such research direction holds the potential to introduce novel therapies for not only managing FS or chronic pain, but also managing FND.
Advancing Image Encryption with a Novel One-Dimensional Chaotic Map
Authors: Li Yuxuan
Published: March 2024

The secure transmission of images is a critical aspect of information security, especially in an era where digital communication is ubiquitous. Image encryption, leveraging the complexity and unpredictability of chaotic dynamical systems, offers a robust means to safeguard image data against unauthorized access. In this study, we introduce a novel one-dimensional chaotic map, referred to as 1D-SCPCM, and conduct extensive experiments to validate its exceptional chaotic properties. Unlike traditional one-dimensional chaotic maps, 1D-SCPCM exhibits enhanced stability and consistency in its chaotic dynamics across various control parameters, making it highly suitable for image encryption tasks. Utilizing the capabilities of 1D-SCPCM, we develop an advanced image encryption scheme to effectively secure digital images. Our findings underscore the potential of 1D-SCPCM as an effective tool for achieving high levels of security in image encryption and as a steppingstone towards more secure and reliable methods of protecting digital information. This research makes a significant contribution to the fields of chaos theory by presenting a novel approach that combines theoretical innovation with practical security solutions, marking a significant advancement in safeguarding sensitive visual data.
GC-MS Analysis of Hexane Extract of Artabotrys
Authors: Kori Pramila , Mehta B. K.
Published: March 2024

Hexane eluate was extracted from the leaves of Artabotrys Odoratissimus (R.Br.). GC-MS analysis revealed the presence of twenty our peaks conforming to twenty-four compounds, out of these twenty compounds were recognized by comparing their retention time and the interpretation of their mass spectra. These compounds are Eicosane, Heneicosane, 1-Methyl Nonadecane, Heptadecane, Dibutylphthslate,3-Methylheneicosane, Eicosane-3-Ene, 2-Methyl eicosane, Docosane, 10-Methyl Hen eicosane, Nonadecane, Tetracosane, Tetratriacontane, Hexadecenoic Acid, Octadecanoic Acid, Bis (2-Ethyl, Hexyl) Phthalate, 1-Docosene, 2-Dodecanone, 1-Nonadecanol, 2,7,10-Trimethyldodecane. The quantitative estimations of each peak were made by estimating area of the peak by a computer, connected with GC-MS instrument
Case Study of Emerging Groundwater Management Issues at the Forefront of Large-scale Production from a Confined Aquifer: The Vista Ridge Project
Authors: Young Steve , Rubinstein Carlos , Johnson Russell
Published: March 2024

Continued population growth, increased demands for water and declining water availability are statewide water concerns in Texas. The development and movement of water from where it is to where it is needed brings with it benefits to the receiving area and concerns for the area of origin. The Vista Ridge project serves as an on-point example and case study of such concerns and processes that can mitigate, in part, negative impacts that are informative to other Texans who will soon be facing similar pressures.. Impacts on the water levels in existing wells made the Vista Ridge Project a focus of significant public discussion in 2022, including Texas House and Senate interim session hearings. This paper spotlights groundwater management issues prominent in the Vista Ridge Project that will likely be of concern with other Texas groundwater projects in the near future. These issues involve well mitigation, significant impacts from groundwater production across groundwater conservation district boundaries, meaningful consideration of nine factors in Texas Water Code §36.108(d), the balance between limiting groundwater production, development of fair share doctrines, the role of the Texas Water Development Board in the
középkorban is ismert gyógynövények használata napjainkban
Authors: Pászk Norbert , Kenderes Rebeka
Published: March 2024

A témaválasztás egyik oka, hogy a tapasztalat alapján a gyógynövények helyes használata nem eléggé elterjedt manapság. Szeretnénk az embereket ösztönözni arra, hogy gyakrabban és több gyógynövényt használjanak megfelelően, bátran kérjék ki fitoterápiás szakember segítségét szükség esetén és merjék igénybe venni a természetes gyógymódokat. Jelen cikkben szekunder kutatásunk során bemutatunk néhány érdekességet a középkori és modern gyógynövényhasználathoz kapcsolódóan, valamint a középkorban is használt gyógynövények közül 5 darabot. Primer kutatásunk során pedig 3 fő gyógynövényekkel foglalkozó szakemberrel készítettünk mélyinterjút a hazai és külföldi gyógynövényekkel kapcsolatos helyzetről. Célunk, hogy szélesebb körben ismertessük a középkorban használt gyógynövények egy részét, azok közül is olyanokra koncentrálva, melyeket ma is használunk. Szeretnénk továbbá ismertetni, milyen jogszabályok vonatkoznak ma a gyógynövények gyűjtésére, termesztésére, felhasználására, valamint mire kell odafigyelnünk ezek feldolgozásakor. Fontosnak tartjuk még, hogy ismertessük, milyen jogszabályok vonatkoznak a fitoterapeuta szakemberekre.
Rekreációs jelleggel úszó edzésre járó 11-17 éves gyermekek gerincének állapota
Authors: Nagyváradi Katalin , Arany Dániel , Szigethy Mónika , Bíróné Ilics Katalin
Published: March 2024

A „legegészségesebb” sportágként számon tartott úszás során a szárazföldi mozgásvégrehajtások közben tapasztalható törvényszerűségek nem érvényesülnek. Nincsenek hirtelen nagy erőbehatások, ütődések, emiatt az ízületek jelentősen kisebb terhelésnek vannak kitéve. Ez a közeg kulcsszerepet játszik a gyermekkorban jelentkező mozgásszervi elváltozások prevenciójában és esetleges rehabilitációjában is.  Kutatásunk célja volt felmérni különböző korosztályokban rendszeresen – rekreációs céllal - úszóedzésre járó gyermekek gerincének fiziológiás állapotát gerincegér (Spinal Mouse) használatával. Vizsgálatunkba két egyesület úszóit vontuk be. Az eredményeink azt mutatják, hogy mintánkban - rendszeres úszás ellenére is - fellelhetők, főként a háti gerinc szakasz középső szegmenseiben, valamint a teljes ágyéki gerincszakaszon gerincmobilitásbéli problémák, a háti gerincszakasz felső szegmensében, valamint a háti gerincszakasz alsó-ágyéki gerincszakasz felső szegmensében mérsékelt tartásbéli gyengeségek. Az eredmények ismeretében nagyobb hangsúlyt kellene fektetni a szárazföldi edzések során a tehermentesített helyzetben történő felületes és mélyhátizomzat erősítésére. Valamint célszerű lenne az úszóedzések kiegészítéseként rendszeresen beiktatni szárazföldi mobilizáló és nyújtó gyakorlatokat.
Body composition and measurement options
Authors: Fritz Réka , Maszlag Annamária , Mayer Lívia , Fritz Péter
Published: March 2024

The most commonly used method for determining nutritional status to date is the BMI (Body Mass Index). From a scientific point of view, as it is based only on body weight and height, it can be misleading in many cases and is of limited use for the professional assessment of health status and obesity. Today there are more modern and accurate methods. Bioimpedance-based body composition assessment (BIA) systems provide detailed information on body weight, muscle and fat mass and water content. The frequency ranges and measurement points used have a major impact on the accuracy of the measurement data, and the Inbody series excels in this respect. Unlike other devices, it can also provide lean body mass and fat mass broken down by limb. Changes in nutritional status can be used as a predictor of disease progression, so the results of body composition measurement have applications in many areas of healthcare. Examples include diet therapy, obesity management, perioperative care, sports nutrition, supplementation of various therapies (oncology, nephrology, diabetology, cardiology, etc.), rehabilitation. Considering all these factors, it would be worthwhile to extend the use of BIA-based devices to the field of primary prevention (e.g. general practitioners, population screening, workplace health promotion).
„Nyakunkon a probléma”?!
Authors: Baloghné Bakk Adrienn , Nagyváradi Katalin
Published: March 2024

Számítógép, mobiltelefon, tablet és internet nélkül elképzelhetetlenek a napjaink, digitális és felgyorsult világban élünk. Eszközeinket folyamatosan figyeljük, általában lefelé nézünk, ez az előretolt fejtartás a természetes pozíciótól eltér, ami deformitásokat okozhat a gerinc nyaki szakaszán. Ez a természetellenes tartás azért lehet veszélyes, mert óriási terhet ró a gerincünkre. Ennek következtében a nyakhajlító izmok megnyúlnak, míg más izmok például a nyak feszítő izmai megrövidülnek. A gerincvédelem, beleértve a nyaki gerincszakaszra irányuló prevenciót - kiemelt része kell, hogy legyen az egyén egészségmegőrzésének.
Enhancing financial performance and risk management in Kazakhstan’s banking sector
Authors: Buzaubayeva Perizat , Orazbayeva Aigul , Alina Gulzhan , Baimagambetova Zamzagul , Kenges Gulzhihan
Published: March 2024

This study aims to assess the impact of regulatory compliance on the effectiveness of risk management and the financial performance of Kazakhstan’s banking sector. Applying Structural Equation Modeling (SEM), the study examines data from Kazakhstani banking institutions, revealing the direct and mediated impacts of regulatory compliance on financial performance, with risk management efficacy as a key intermediary. The analysis identifies a significant direct relationship between regulatory compliance and risk management efficacy (coefficient: 0.45, p-value: < 0.001), suggesting that compliance efforts substantially bolster risk management capabilities. The impact of risk management efficacy on financial performance is also notable (coefficient: 0.35, p-value: < 0.001), confirming its crucial role in financial success. Additionally, a direct, though less pronounced, influence of regulatory compliance on financial performance is observed (coefficient: 0.20, p-value: 0.004). The model’s explanatory power is reflected in an R-squared value of 0.248, indicating that it accounts for approximately 24.8% of the variability in financial performance. These findings underline the critical role of regulatory adherence and effective risk management in ensuring financial success, offering strategic insights for banking operations in Kazakhstan.
Does behavioral biases matter in SMEs' borrowing decisions? Insights from Morocco
Authors: Ayad Khalid , Touil Anass , El Hamidi Nabil , Dobli Bennani Khaoula
Published: March 2024

Bank financing decisions by small and medium-sized enterprises (SMEs) are crucial to their growth and survival, particularly in emerging economies such as Morocco. This study aims to assess the impact of behavioral biases on these decisions, an area little explored in the existing financial literature. The main objective is to analyze how behavioral biases such as overconfidence, risk aversion, confirmation bias, anchoring, and managerial myopia biases influence bank financing decisions of Moroccan SMEs. The approach adopted is quantitative and uses robust least squares regression to analyze data collected from 167 Moroccan SMEs. The results reveal that overconfidence and anchoring have a significant positive impact on the propensity to take out bank loans, while risk aversion and confirmation bias have a negative effect. Managerial myopia had no significant influence. Control variables such as past financial performance, the length of the banking relationship, and lower risk also positively influence the financing decision.
Exploring the role of corporate governance in driving financial performance: An empirical investigation of Nepalese commercial banks
Authors: Dongol Padam , Kumar Shrestha Sajeeb
Published: March 2024

This study delves into the substantial impact of corporate governance practices on a company’s financial performance, focusing specifically on Nepalese commercial banks in the Kathmandu Valley. With 419 participants from all 27 «A» grade commercial banks, the study concentrates on employees currently working in these banks, particularly top-level staff such as managers, department heads, and officers. The primary objective is to investigate the role of corporate governance in driving financial performance, using Return on Assets (ROA) and Return on Equity (ROE) as financial performance indicators of banks. The study explores various factors influencing corporate governance’s impact, including corporate governance policies, disclosure policies, board size, income diversity, and ethnic diversity. Data collection involves primary data from participants associated with the banks, and the analysis is conducted using the Statistical Package for the Social Sciences (SPSS). Descriptive, correlation, and regression analyses are employed to understand the relationship between corporate governance and financial performance variables. Notably, regular evaluations of the board of directors are found to have a beneficial impact on financial performance. A bank’s transparency in sharing performance information exhibits a stronger positive correlation with ROE (R=0.183) compared to ROA (R=0.060), suggesting that ROE is more sensitive to disparities in information availability. Furthermore, the study identifies a negative impact of board size on financial performance, with low-income diversity positively influencing it and board ethnic diversity exerting a negative and statistically significant influence.
MODELO DE AVALIAÇÃO DE APLICATIVOS EDUCACIONAIS: AVALIANDO APLICATIVOS DE QUÍMICA ORGÂNICA DA GOOGLE PLAY®
Authors: de Oliveira Vanessa , Leite Bruno
Published: March 2024

EDUCATIONAL APPLICATIONS EVALUATION MODEL: EVALUATING GOOGLE PLAY® ORGANIC CHEMISTRY APPS. Over the years it has been possible to notice the growth of applications for educational purposes available on digital platforms. Many of these apps are used in teaching and learning processes, however few are evaluated regarding their theoretical and practical aspects. In this context, in chemistry teaching, specifically the area of organic chemistry, it is inferred that apps can help build knowledge of this Science through visualization and interaction with them, but little is discussed about how these apps are evaluated in practice. Therefore, the present work proposes a new model based on technical and pedagogical aspects, based on evaluation models for educational digital games and Bloom’s digital taxonomy, called the educational application evaluation model (EAEM). In addition, organic chemistry applications available on the Google Play® platform through EAEM are analyzed. The results indicate that the EAEM was efficient in evaluating organic chemistry apps, configuring itself as an alternative for choosing educational apps regardless of the subject, where teachers can analyze the characteristics of the apps according to their pedagogical activities.
HPLC-DAD Validation Method for Quantifying Gallic Acid in the Aerial Parts of Schinus terebinthifolius
Authors: Martins Christiane , Silva Liliane , Campos Emmanuel , Borges Leonardo , Fiuza Tatiana , de Paula José
Published: March 2024

Schinus terebinthifolius Raddi (Anacardiaceae), commonly known as “pimenta rosa”, “aroeira da praia”, “aroeira”, “aroeirinha”, and “cabuí” is frequently used in traditional medicine to address various conditions, including skin wounds, ulcers, tumors, diarrhea, arthritis, as well as urinary and respiratory tract infections. This study aimed to develop and validate an analytical method using high-performance liquid chromatography with diode array detector (HPLC-DAD) for quantifying gallic acid (GA) in methanolic extracts of S. terebinthifolius leaves, branches, and fruits. The chromatographic separations utilized a reversed-phase Zorbax Eclipse XDB-C18 column with an isocratic elution mode of acetonitrile/methanol/water acidified with 0.2% formic acid. The flow rate was 0.8 mL min-1, and detection occurred at 254 nm. The developed HPLC-DAD method demonstrated selectivity, with a GA retention time of 5.263 min and absorption maxima at 220 and 271 nm. The method exhibited high linearity (coefficient of 0.9996), precision (relative standard deviation (RSD) values < 5%), and robustness. Accuracy ranged from 100.28 to 111.71%, with an average recovery of 105.41% and an average RSD of 3.46%. These validated results play a crucial role in assessing and standardizing raw materials containing S. terebinthifolius, emphasizing the reliability of the developed HPLC-DAD method for GA quantification in different plant parts.
Organofunctionalized Nb2O5 Nanoparticles for Photodynamic Therapy against A549 Cancer Cells
Authors: Oliveira Ronaldo , dos Santos Luiz Henrique , Ghasemishahrestani Zeinab , Pereira Marcos , Forero Josué Sebastián , Simões Grazieli , Ribeiro Emerson , Corrêa Rodrigo José
Published: March 2024

Niobium pentoxide shows an interesting reactivity that allows the control of different aspects of its morphology and chemistry. In this study, Nb2O5 nanoparticles were modified with protoporphyrin IX (PPIX) and tris(ethynylphenyl) pyrene derivative (PyPh3) by using 3-aminopropyltriethoxysilane as linkage group and used as photosensitizers against lung cancer. The antitumor photoactivity against the A549 tumor cell line as a model of in vitro study showed half maximal inhibitory concentration (IC50) ca. 15 μmol L-1 for both materials and the absence of dark activity, indicating the viability of dye-modified Nb2O5 as a photodynamic therapy (PDT) agent.
Preparation, Characterization, and Hepatoprotective Activity Evaluation
of Quercetin-loaded Pluronic® F127/Chitosan-Myristic Acid Mixed Micelles
Authors: Telange Darshan R. , Kamdi Seema , Hemke Atul T. , Pethe Anil M. , Lambole Vijay B. , Telrandhe Umesh B.
Published: March 2024

Background::

Quercetin (QTN) is a flavonol antioxidant found in foods, medicinal
plants, fruits, vegetables, and beverages. QTN oral consumption produces several biological effects,
including antioxidant, cardioprotective, anti-apoptotic, anti-cancer, neuroprotection, anti-hypertensive,
and chemo preventive.

Objective::

The study aimed to prepare Pluronic®F127/chitosan-myristic acid copolymer
(PF127/C-MAc)-based mixed micelles (QTN MM) to improve the biopharmaceutical and hepatoprotective
potential of QTN.

Methods::

QTN MM was developed employing thin-film hydration and optimized using full factorial
design (FFD). Optimized QTN MM was analyzed using scanning electron microscopy (SEM),
differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FT-IR), powder
x-ray diffractometry (PXRD), in vitro dissolution, ex vivo permeation, and in vivo antioxidant activity
in carbon tetrachloride (CCL4)-induced albino rats.

Results::

PF127/C-MAc ratio (1:1) with CMC value ~ 5 μg/mL showed the suitability for MM.
Characterization supported the formation of MM. QTN MM revealed prominent encapsulation efficiency
and drug loading of about ~ 95.10% and ~ 12.28% w/w, respectively. MM spherical
shape of QTN with a smaller particle size of ~ 34.08 nm and a higher zeta potential of ~ 36.24 nm
indicated excellent physical stability. Dissolution and ex vivo permeation results revealed higher
dissolution and permeation of QTN MM compared to QTN and PM. In vivo antioxidant activity
suggested that QTN MM at (~ 20 mg/kg, p.o.) restored the enhanced marker enzyme level compared
to QTN.

Conclusion::

The findings demonstrate that developed QTN MM could be used as an alternative
nanocarrier to increase the biopharmaceutical and hepatoprotective potential of QTN and other
flavonoids.
A Snapshot of Biomarkers in Psoriasis
Authors: Abhale Krushna , Veeranjaneyulu Addepalli , Desai Shivani
Published: March 2024

:

A persistent long-standing, inflammatory skin condition that is brought on by a variety
of factors is psoriasis. It is distinguished by itchy, scaly, reddish plaques, particularly on areas of
the body that are frequently chafed, including the extensor sites of the limbs. Recent developments
in molecular-targeted therapy that use biologics or small-molecule inhibitors can effectively
cure even the worst psoriatic indications. The outstanding clinical outcomes of treatment help to
clarify the disease's detrimental consequences on quality of life. Biomarkers that identify deep remission
are essential for developing uniform treatment plans. Blood protein markers such as
AMPs that are consistently quantifiable can be very helpful in routine clinical practice. The
metabolic pathways involve biomarkers that can not only help diagnose psoriasis in a clinical setting
but also indicate its severity based on the levels present in the body. Machine learning and AI
have made a diagnosis of the expression of genes as biomarkers more accessible. In this article,
biomarkers, as well as their key role in psoriasis, are discussed
The Neurochemical Anatomy of Runway Acquisition and Extinction
Authors: Lalonde Robert , Strazielle Catherine
Published: March 2024

A review is presented as to the neurochemical basis of the straight runway task, usually
consisting of an acquisition phase followed by an extinction phase. During the acquisition of the
appetitive runway task, running speeds from the start box to the goal box progressively increase
over trials and then decrease when the reward is withheld. Runway extinction is susceptible to lesions of the limbic system, including the medial frontal cortex, the hippocampus, the septum, the
amygdala, and the dorsomedial thalamus. When specific neurotransmitter systems are examined,
extinction was delayed when noradrenaline transmission was impeded, perhaps involving noradrenergic projections to the hippocampus and neocortex. Extinction was likewise delayed after either
facilitation or blocking of dopamine transmission, a result implicating an inverted U-shaped function caused by dopamine’s role in behavioral activation or reward processes. Extinction was also
delayed by indirect GABAA receptor agonists injected during acquisition, explained by druginduced disinhibitory tendencies. This simple paradigm may provide information about the effects
of a physiological manipulation on both cognition and emotion.
Producción y consumo sostenible: avances y la agenda pendiente en el Perú
Authors: Rebatta Nieto Javier Luis
Published: March 2024

El Perú, como parte de las Naciones Unidas, tiene un compromiso que cumplir con la sostenibilidad del medio ambiente. La Agenda 2030 y los Objetivos del Desarrollo Sostenible (ODS) son ambiciosos y exigen compromisos y acciones concretas para alcanzar las metas planteadas. A pocos años del cumplimiento del plazo, los avances son preocupantes en la mayoría de los indicadores de las metas de los ODS, lo que implicará un esfuerzo adicional y la generación de alianzas público-privadas para garantizar la conservación de nuestro planeta. En el presente documento se analizan los avances logrados en el Perú en el ODS 12 “Garantizar modalidades de producción y consumo sostenible”, que ha tenido una importante participación de la empresa privada con los reportes de sostenibilidad, y se busca plantear la agenda pendiente para lograr las metas de la Agenda al 2030.
Análisis de la eficacia de los programas sociales alimentarios y su efectividad para la reducción de la pobreza, 2012 -2021
Authors: Quispe Llanos Renán , Chung Alva Víctor Manuel
Published: March 2024

La investigación aborda la evaluación de la eficacia de los programas sociales alimentarios en Perú desde 2012 hasta 2021. Los hallazgos indican que el programa "Qali Warma" exhibe deficiencias en la gestión del presupuesto, ya que el incremento de beneficiarios se atribuye a la inclusión de personas no calificadas como pobres. En cuanto a "Cuna Más", se observa una disminución en su efectividad en los últimos años, principalmente debido al impacto de la pandemia. Por otro lado, el programa "Vaso de Leche", a pesar de recibir menos recursos, demuestra su eficacia al contribuir al mejoramiento del bienestar social. En contraste, la evolución del programa de salud no ha tenido tanto éxito para garantizar una reducción significativa de la anemia y la desnutrición crónica en los niños. El análisis de regresión logística revela que estos programas se implementan preferentemente en áreas urbanas y no están necesariamente asociados con los ingresos per cápita familiar, excepto en el caso del programa "Cuna Más".
El crecimiento de China y la trampa del ingreso medio en Latinoamérica
Authors: Valdiglesias Oviedo Jhon
Published: March 2024

El objetivo principal de este artículo es identificar los factores que explican las disparidades en el PIB per cápita entre las economías de América Latina y la economía de China, especialmente considerando el notable crecimiento económico de esta última en contraste con el estancamiento experimentado por los países latinoamericanos, que se encuentran atrapados en un ingreso per cápita estimado como de mediano nivel. Para alcanzar este objetivo, se emplea un modelo econométrico utilizando el método de panel data, utilizando principalmente indicadores de desarrollo disponibles en la base de datos del Banco Mundial. Los resultados obtenidos revelan que la calidad de las instituciones constituye un factor determinante en las disparidades económicas entre las economías mencionadas, resaltando las mejoras institucionales observadas en China en los últimos años. Como resultado de nuestras conclusiones, se recomienda que los países de América Latina consideren la implementación de estrategias institucionales similares a las que han permitido a China superar los factores críticos que inhibían y limitaban su ingreso per cápita.
Barriers to Health Self-Management Among Older People with Hypertension and Diabetes in Institutions in China: A Phenomenological Study
Authors: Liu Rong , Dahlan Akehsan , Mohd Fahmi Teng Nur Islami , Zhan Xingxin Zhan
Published: March 2024

The objective of this qualitative study is to explore the barriers to self-management among older people with hypertension and diabetes in institutional settings from the perspectives of both patients and health professionals in China.  A qualitative phenomenological study used semi-structured face-to-face interviews involving eight older persons and ten health professionals.  Thematic analysis revealed two main themes: 1) individual-related factors and 2) limited social support.  Tailored interventions considering these multifaceted barriers can positively impact the quality of life and health outcomes for older individuals dealing with hypertension and diabetes in institutional settings.
Effect of the Occupational Engagement Home Program (MyHOeME©) for Older Persons in the Community
Authors: Dahlan Akehsan , Haidhir Harnisha , Tengku Makhtar Tengku Mohd Asri , Sahid Muhammad Hidayat
Published: March 2024

Malaysia faces a pressing issue as its older population is projected to reach 16% by 2030.  While global and national initiatives focus on health and independence, there exists a gap in structured activities for older persons.  Our study introduces MyHOeME, a 5-week program designed by an occupational therapist, which addresses the physical, cognitive, and social facets of ageing through personalized activities.  This quasi-experimental study involved 78 older persons in the community.  The results indicate a significantly enhanced health-related quality of life after attending MyHOeME, emerging as a promising solution for the well-being of Malaysia's ageing population.
An Integrated Therapeutic Approach To Enhance Quality of Life: A Case Study
Authors: Kok Yuen Yee , Tong Hoey Chin Christy , Liu Jia
Published: March 2024

Cognitive-behavioural therapy (CBT), attachment theory, and humanistic psychology improve mental health by restructuring individuals’ cognition, relationship dynamics, and self-exploration. This study aimed to examine the relationships between CBT, attachment theory, and humanistic psychology in improving the client’s mental well-being. This study adopted qualitative methods, including observational data, counselling transcripts, and interviews, involving only one client. The findings showed that integrating therapeutic methods effectively addresses profound psychological challenges. The findings indicate a positive progression in the client's overall quality of life, suggesting the potential of integrated approaches in fostering meaningful counselling.
Effects of Core Stability Training on Muscle Physiology among Adults with Low Back Pain
Authors: Pipeng Lin , Zahari Zarina , Azizan Azliyana , Yajun Yang
Published: March 2024

Background: The effects of core stability training (CST) on muscle physiology in adults with chronic low back pain(CLBP) are still debatable. Objectives:  To explore the effects of CST on muscle physiology in adults with CLBP. Methods: Eligible studies published in English from inception to October 2023 were extracted from PubMed, Web of Science, and Scopus in this review. Pedro was used for scoring and followed the PRISMA guidelines. Findings: Core muscle strength (1 study), thickness (4 studies), and activation (6 studies) favored CST. Conclusion: CST was more effective in improving core muscle strength, and activation for patients with CLBP.
Breaking the Glass Code : Mentorship-Driven Empowerment in Malaysia’s ICT Sector
Authors: Shaari Noremi , Subramaniam Geetha , Rosnan Herwina , Ramli Suriana , Premananto Gancar Candra
Published: March 2024

This study explores the role of mentoring in advancing women’s careers in Malaysia's ICT sector, where women are underrepresented in leadership roles. This conceptual study is primarily centered on examining the role of mentorship in advancing women's careers in Malaysia's Information and Communication Technology (ICT) sector. It examines societal, organizational, work-life balance, and individual factors influencing the career paths of women in the ICT sector in Malaysia. This study is significant in providing the importance of promoting diversity in the workforce, in line with the Sustainable Development Goal  SDG 5 i.e. Gender Equality.
Hot Topics on Nutrition in IBD
Authors: Soares Caroline , Ministro Paula
Published: March 2024

Inflammatory bowel diseases (IBD) affect primarily the bowel, but they are multisystemic diseases with a wide range of extraintestinal manifestations and complications. Nutritional imbalance occurs frequently in patients with IBD. The spectrum of malnutrition goes from undernutrition (low protein-caloric intake, disease-related malnutrition, micronutrient deficiencies) to overnutrition and obesity. The nutritional status of patients with IBD is increasingly recognized as a key aspect of the treatment and must be addressed in all patients. The screening and correction of the deficiencies should be individualized. Except for enteral nutrition in pediatric Crohn’s disease, no clinical evidence supports specific diets. Nevertheless, the role of personalized nutritional interventions as an adjunct therapy is well established. Compelling new data points to a key role of diet in gut inflammation directly or through modulation of intestinal microbiota. It will be of utmost importance to have well-designed longitudinal studies on dietary interventions alone or combined with current therapies. This review summarizes topics such as the spectrum of malnutrition, the evidence behind the concept of diet as an IBD cause, and the role of diet in IBD therapy.
Analysing the Easing Language in Business English General Language Talks under the Perspective of Relationship Management Theory
Authors: Li Jialu
Published: March 2024

With the rapid development of globalisation, business communication has become more and more frequent in the international arena. In business English conversation, moderating language plays an important role as a communication strategy. Based on the perspective of relationship management theory, this paper explores the functions and strategies of de-escalation in business English talks. The results of the study show that de-escalation helps to establish and maintain good business relationships in business scenarios, and also positively affects the outcome of the talks. Finally, the paper puts forward some suggestions for the use of moderated language in business English talks to help business people communicate better across cultures.
A Study on English Translation of Poems and Lyrics by Mao Tse-tung from the Perspective of Metaphor
Authors: Huang Yanlin , Li Yonglan
Published: March 2024

Mao Tse-tung is a great revolutionist, and his poems have always been praised as “A poem wins a country”. Metaphor is a process to understand and experience one thing through another thing, with its core to create undiscovered connections between ontology and metaphor, it is to combine two dissimilar things together. Poems and Lyrics written by Mao Tse-tung are rich in metaphors, this paper compares and studies four English translations of Mao Tse-tung’s poems(translated by Xu Yuanchong, Foreign Languages Press, Wang Huiming and Gu Zhengkun) from the perspective of metaphor at conceptual level, and discusses how translator deal with verbal metaphors and nominal metaphors. The results find that most of the translators choose to retain metaphors in the target language in order to accurately convey the information of the poems, which is suitable to translate metaphors in the poems.
Navigating New Horizons: The Future of International Student Mobility in the Post-Pandemic World
Authors: Li Yingyang , Zhao Zirui
Published: March 2024

The global higher education landscape has undergone significant change in the wake of COVID-19. There’s been a notable surge in students opting for more affordable programs, alongside a considerable rise in those pursuing overseas education for immigration purposes. Countries like Canada and Australia have responded by easing visa constraints to lure international students. Meanwhile, India and China, as two key players in sending students abroad, are experiencing divergent trajectories. While China is fostering its domestic education sector and implementing policies to draw in international students, its population is expected to decline. Conversely, the rapidly growing youth population in India offers a favorable opportunity for overseas students. For nations reliant on the overseas education sector, striking a balance between the economic benefits and local employment impacts is crucial, while also addressing market share challenges posed by China and India. Exploring alternative markets is imperative. Nigeria, Kenya, and other nations show high growth potential, while the rising middle class in Latin America offers another potential source market. Kazakhstan emerges as a notable contender, with its pre-pandemic economic expansion and government initiatives promoting international student mobility and ambitious targets. The declining cost of studying abroad reflects not only the economic challenges facing the global education sector but also a democratization of access to international education, no longer confined to affluent families. A noticeable rise of international students from Asian countries—such as China, Russia, Japan, and South Korea—indicates a slow shift in the market share away from popular study locations. This shift underscores a broader trend of diversification in the global higher education landscape.
Effect of Zhishenyuanhu Anticoagulant Formula on Hypercoagulability in Rats with Qi Stagnation and Blood Stasis and Arterial and Venous Thrombosis in Rats
Authors: He Xingting , Deng Xuemei , Chen Shuang , Xiang Kewei , Wen Qinglian , Wan Runlan , Xu Fujiang , Yang Hongru
Published: March 2024

Background: Tumor patients present with hypercoagulable blood and are at risk of venous thromboembolism (VTE). We explored the effect of Zhishenyuanhu anticoagulant formula（ZSYH）on hypercoagulability in rats with qi stagnation and blood stasis and thrombosis in rats.Methods: Part I. Epinephrine (0.6 mg/kg, hypodermic injection, h.i.) was administered every day for 7 days. Six groups were gavaged with saline, saline, rivaroxaban, low-dose, medium-dose, and high-dose ZSYH every day. We collected rats’ daily body weight, food intake, clotting time (CT), coagulation and hemorheology results. Part II. Six groups of rats were given the same drugs as in part I for 7 days. Half of rats in each group were used to construct a common carotid artery thrombusis model, while the other half were used to construct an inferior vena cava thrombusis model. Results: ZSYH caused decreases in FIB, shear rate 1, whole blood low shear relative index, and RE. The high dose of ZSYH caused decreases in wet and dry weight of arterial and venous thrombosis.Conclusion: ZSYH is effective in treating hypercoagulability in rats with qi stagnation and blood stasis. The high dose of ZSYH prevent the development of arterial thrombosis and venous thrombosis.
Взаимодействие подсистем: первичной и синтезирования в системе многоуровневой базовой групповой технологии. Часть 2
Authors: Ракунов Ю.П. , Абрамов В.В. , Ракунов А.Ю.
Published: March 2024

Приведены научные принципы разработки и совершенствования построения первичной подсистемы и синтезирования многоуровневой базовой групповой технологии (МБГТ). Проведено развитие основных подсистем МБГТ. Дано описание методики параметрической оптимизации типажей унифицированного режущего инструмента (УРИ), спроектированных для групповой обработки и режимов оптимального резания конструкционных и труднообрабатываемых материалов на прецизионных токарных универсальных, станках с ЧПУ и автоматах продольного точения.
Изучение метода повышения прочности филамента PLA
Authors: Петров П.А. , Бурлаков И.А. , Полшков П.А. , Чибизов М.А. , Сапрыкин Б.Ю.
Published: March 2024

Приведены результаты сравнительного анализа прочностных характеристик заготовок, полученных с применением 3D-печати из филамента PLA фирмы ESUN, которые были подвергнуты отпуску при различных температурах.
Admission Fortune Using Machine Learning & Designing an Interactive Chatbot for Educational Assistance
Authors: Shahane Prof. P. R. , Sumit Pedgulwar , Prathmesh Patil , Sujal Oswal
Published: March 2024

Abstract: The proposed system is a Student Admission Rank-Based College Selection Prediction platform that aims to assist students in making well-informed decisions about their college applications. It is a predictive model that uses machine learning algorithms to estimate the likelihood of a student's admission to different colleges based on their academic performance and the admission criteria of those colleges. The proposed system is expected to empower students by providing them with valuable insights into their chances of admission to different colleges. Students can use this information to strategize their college applications and increase their likelihood of acceptance to colleges that align with their academic aspirations and preferences.
Respuesta sobre la bioequivalencia en los medicamentos bioterapeúticos
Authors: Martínez José David , Cavanzo Henao Paula , Sobrino Fidel , Ramírez Sergio , Arango Gabriel , Zuluaga Andrés , Rendón Laura
Published: March 2024

Hemos tenido la oportunidad de leer su carta relacionada con nuestro artículo de revisión: “Medicamentos bioterapeúticos: uso de toxinas botulínicas en la era de biosimilares” (1). Queremos manifestar nuestro acuerdo con sus comentarios sobre la relevancia del tema en nuestro medio, así como con sus reflexiones sobre la intercambiabilidad de medicamentos y la necesidad de precisar muy bien los conceptos en la materia.
En particular, usted hace referencia a la confusión que puede generar la frase de nuestra conclusión: “los medicamentos biológicos no son intercambiables entre sí, aunque demuestren bioequivalencia” Con interés leímos cómo muchos de los compañeros se confundieron con la última parte de la frase pues resulta contradictorio, ya que como usted menciona clásicamente “los estudios de bioequivalencia se realizan para demostrar que el medicamento genérico es equivalente e intercambiable con el medicamento original”.
Costos médicos directos de los pacientes con ataque cerebrovascular isquémico en un hospital público de Bogotá, Colombia
Authors: Zapa Pérez Neiry María , Martínez Lemus Juan Diego , Torres Ramírez Alejandra , Jiménez Monsalve Claudio Alejandro
Published: March 2024

Introducción: el ataque cerebrovascular isquémico (ACVi) es la segunda causa de muerte en Colombia. Se estimó que los costos asociados al ACVi podrían alcanzar los COP 5000 millones durante el 2019.
Objetivo: describir los costos médicos directos de los pacientes que sufren de ACVi en una institución en Bogotá durante el 2020.
Metodología: estudio de corte transversal que analiza los costos médicos directos de la atención hospitalaria de adultos que sufrieron un ACVi durante el 2020. Se compararon los costos, la estancia y los desenlaces clínicos de pacientes que recibieron trombólisis frente aquellos que no la recibieron.
Resultados: los costos directos relacionados con 132 pacientes con ACVi fueron COP 1.218.970.831 en el año 2020 en nuestra institución. El costo promedio por paciente fue COP 7.845.073. Entre los eventos hospitalarios, las imágenes diagnósticas y otros métodos diagnósticos representaron la mayor proporción de costos (40?%), entre los que se destacó la angiotomografía de cabeza y cuello. La severidad del ACV influyó significativamente en los costos totales (p?=?0,018), así como en los costos de los medicamentos (p?<?0,001), procedimientos (p?<?0,001) y la estancia hospitalaria (p?<?0,029). Los pacientes sometidos a trombólisis resultaron 1,33 veces más costosos que aquellos con manejo médico (p?<?0,001), sin que ello afectara de manera significativa la duración de la estancia ni la tasa de letalidad.
Conclusión: la trombólisis intravenosa en el ACVi implica un aumento significativo en los costos directos, pero reduce la carga de discapacidad en los pacientes tratados. Los costos se incrementan con la severidad del ACVi y la realización de algunos procedimientos adicionales.
SEJARAH PERKEMBANGAN PEMBELAJARAN BAHASA MELAYU DI JEPUN
Authors: Moriyama Mikihiro
Published: March 2024

The Japanese started learning Malay at the end of the 19th century. The first Malay primer was published in the 1900s. A number of books and dictionaries of Malay were published thereafter exceeding 200 titles. The Japanese began to sail to the Southeast Asian region, especially the Malay peninsula and the Dutch East Indies’ islands after the Tokugwa Shogunate administration ended and Meiji period began in 1868. The Japanese moved to Nanyo (the southern regions) of Japan to seek their fortune as small shopkeepers, peddlers and some even became prostitutes. Japanese enterprises were stimulated by the so-called Nanshin Ron (Advance Southward Ideology), which prevailed in the 1920s and 1930s. They gradually operated rubber plantations and iron mine companies and other businesses as well. In terms of economic activities, it was necessary to learn the languages of the locals for business communications and business interests. They thought Malay was the most prominent communication tool among the many languages used in the southern regions. For this purpose, the Japanese began learning Malay in schools in Japan. The peak of Malay learning was the time of Japanese expansion policy based on militarism in the 1940s. The total number of publications of primer and dictionary reached more than 50 titles during this period. After the end of the Second World War, Malay language learning did not receive much attention in Japanese society but it changed when business interest in Southeast Asia became stimulated by government policy including war reparations. The article provides a rough sketch of Malay language learning in Japan in the first place and in the final part discusses how Japanese government and society have maintained and promoted their own language and identity as a policy to develop the nation and state in terms of language teaching in both foreign languages and national language.
Family Medicine Resident Education About Health Disparities Associated With Incarceration: A CERA Research Study
Authors: Hofmeister Sabrina , Johnston Bryan , Treat Robert
Published: March 2024

Background and Objectives: We submitted research questions to the Council of Academic Family Medicine Educational Research Alliance (CERA) to assess the format of family medicine resident education about health disparities associated with incarceration and the perceived efficacy of efforts to prepare graduates for competent care of formerly incarcerated patients in practice. We think this is a universal problem, and current efforts are insufficient.
Methods: We evaluated data as part of the fall 2022 CERA survey of program directors (PDs). We reviewed descriptive statistics, generated comparative analysis, and reported relational analysis. We analyzed internal structure with principal component analysis and inter-item reliability.
Results: A total of 286 out of 678 (42%) eligible PDs completed the survey. Most respondents felt that educating residents about health disparities associated with incarceration was important and that residents would welcome that education. However, PDs lacked existing curricula. PDs did not think that medical school graduates were well-prepared in this area, and ambivalence existed about whether residency graduates were well-prepared to treat formerly incarcerated patients upon graduation. Comparative analysis revealed differences in responses based on the type of program, the program and community size, and the PD demographics.
Conclusions: PDs acknowledged the importance of training residents about health disparities associated with incarceration and about care for formerly incarcerated patients in practice. However, they identified a gap between what was currently offered and what is needed to impact perception of resident readiness upon graduation. This training was felt to be most important in university-based programs with 31+ residents in US communities of greater than 150,000 people. We found no difference based on geographic location.