bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-Organization of Semifluorinated Alkanes and Related Compounds at Interfaces: Thin Films, Surface Domains and Two-Dimensional Spherulites
Authors: Liu Xianhe , Riess Jean G , Krafft Marie Pierre
Published: February 2018

After a brief reminder of the specific properties of fluorocarbons, fluorinated chains and molecular fluorocarbon-hydrocarbon diblocks (semifluorinated alkanes, CnF2n+1CmH2m+1, FnHm) that account for their exceptional aptitude for self-organization, we review recent advances on the self-assembled surface nanodomains that FnHm diblocks form on water and solid surfaces, their shape and size characteristics, and their hierarchical organization into structures of higher complexity. Remarkably indeed, FnHm diblocks, when spread as Langmuir monolayers on water, self-assemble into circular mesoscopic nanodomains that exist even in the absence of lateral pressure, and self-organize into regular hexagonal arrays upon compression. These surface domains can be transferred essentially unchanged onto solid surfaces. They can also be obtained by direct casting or spin coating of solutions of diblocks on solids, or by spontaneous formation on liquid crystals. The nanodomains retain their size, shape and organization upon compression and, amazingly, even beyond the collapse of their Langmuir monolayers. The domain-patterned films display uncommon rheology, with predominantly elastic monolayers, and two-dimensional gels were generated, including at zero surface pressure. The formation and behavior of surface domains from related tri- and tetrablocks have also been reported. A tetrablock afforded the first example of pressure-driven stacking of self-assembled nano-objects. The domain-patterned films constitute attractive templates for organizing nanoparticles in components of electronic devices and sensors, and for fabricating ordered mesoporous solids. Most recently, a novel aggregation mode was found for FnHm diblocks, namely their crystallization into micron-size polycrystalline two-dimensional radial and/or ring-banded spherulites. Applications in medicine and materials science are being investigated.
Virtual-screening workflow tutorials and prospective results from the Teach-Discover-Treat competition 2014 against malaria
Authors: Riniker Sereina , Landrum Gregory A. , Montanari Floriane , Villalba Santiago D. , Maier Julie , Jansen Johanna M. , Walters W. Patrick , Shelat Anang A.
Published: February 2018

The first challenge in the 2014 competition launched by the Teach-Discover-Treat (TDT) initiative asked for the development of a tutorial for ligand-based virtual screening, based on data from a primary phenotypic high-throughput screen (HTS) against malaria. The resulting Workflows were applied to select compounds from a commercial database, and a subset of those were purchased and tested experimentally for anti-malaria activity. Here, we present the two most successful Workflows, both using machine-learning approaches, and report the results for the 114 compounds tested in the follow-up screen. Excluding the two known anti-malarials quinidine and amodiaquine and 31 compounds already present in the primary HTS, a high hit rate of 57% was found.
Evaluation of defense strategy against Influenza A in cell line models
Authors: Antonova Ekaterina , Glazova Olga , Gaponova Anna , Eremyan Aykaz , Grebenkina Natalya , Zvereva Svetlana , Volkova Natalya , Volchkov Pavel
Published: February 2018

Background:Influenza virus can cause both seasonal infections and unpredictable pandemics. Rapidly evolving avian H5N1 virus is getting increasingly infective for humans. Since avian Influenza can be transmitted by domestic birds, serving as a key link between wild aquatic birds and humans, an effective measure to control the influenza transmission would be eradication of the infection in poultry. It is known that the virus penetrates into the cell through binding with the terminal oligosaccharides - sialic acids (SA) - on the cell surfaces. Removal of SA might be a potential antiviral strategy. An approach to developing chicken lines that are resistant to influenza viruses could be the creation of genetically modified birds. Thus it is necessary to select a gene that provides defense to influenza. Here we have expressed in cells a range of exogenous sialidases and estimated their activity and specificity towards SA residues.

Methods:Several bacterial, viral and human sialidases were tested. We adopted bacterial sialidases fromSalmonellaandActinomycesfor expression on the cell surface by fusing catalytic domains with transmembrane domains. We also selected Influenza A/PuertoRico/8/34/H1N1 neuraminidase and human membrane sialidase (hNeu3) genes. Lectin binding assay was used for estimation of a α (2,3)-sialylation level by fluorescent microscopy and FACS.  

Results:We compared sialidases from bacteria, Influenza virus and human. Sialidases fromSalmonellaand Influenza A neuraminidase effectively cleaved α (2-3)-SA receptors. Viral neuraminidase demonstrated a higher activity. Sialidases fromActinomycesandhNeu3did not show any activity against α (2-3) SA under physiological conditions.

Conclusion: Our results demonstrated that sialidases with different specificity and activity can be selected as genes providing antiviral defence. Combining chosen sialidases with different activity together with tissue-specific promoters would provide an optimal level of desialilation to prevent infection. Tissue specific expression of the sialidases could protect domestic birds from infection.
The relationship of cigarette smoking in Japan to lung cancer, COPD, ischemic heart disease and stroke: A systematic review
Authors: Lee Peter N. , Forey Barbara A. , Thornton Alison J. , Coombs Katharine J.
Published: February 2018

Background:  To present up-to-date meta-analyses of evidence from Japan relating smoking to major smoking-related diseases. 

Methods:  We restricted attention to lung cancer, chronic obstructive pulmonary disease (COPD), ischemic heart disease (IHD) and stroke, considering relative risks (RRs) for current and ex-smokers relative to never smokers.  Evidence by amount smoked and time quit was also considered.  For IHD and stroke only, studies had to provide age-adjusted RRs, with age-specific results considered.  For each disease we extended earlier published databases to include more recent studies.  Meta-analyses were conducted, with random-effects RRs and tests of heterogeneity presented. 

Results:  Of 40 studies, 26 reported results for lung cancer and 7 to 9 for each other disease.  For current smoking, RRs (95%CIs) were lung cancer 3.59 (3.25-3.96), COPD 3.57 (2.72-4.70), IHD 2.21 (1.96-2.50) and stroke 1.40 (1.25-1.57).  Ex-smoking RRs were lower.  Data for lung cancer and IHD showed a clear tendency for RRs to rise with increasing amount smoked and decrease with increasing time quit.  Dose-response data were unavailable for COPD and unclear for stroke, where the association was weaker. 

Conclusions:  Compared to studies in other Asian and Western countries, current smoking RRs were quite similar for IHD and stroke.  The comparison is not clear for COPD, where the Japanese data, mainly from cross-sectional studies, is limited.  For lung cancer, the RRs are similar to those in other Asian countries, but substantially lower than in Western countries.  Explanations for this are unclear, but less accurate reporting of smoking by Japanese may contribute to the difference.
Pathway to care for drug resistant tuberculosis cases identified during a retrospective study conducted in high TB burden wards in Mumbai
Authors: Lobo Eunice , Shah Shimoni , Rangan Sheela , Dholakia Yatin , Mistry Nerges
Published: February 2018

Background: Mumbai is witnessing a rising incidence of all forms of drug resistant tuberculosis (DR-TB).

Methods: A population-based, retrospective study was conducted between April and July 2014, in 15 high TB burden wards in Mumbai, to capture the patient pathways to TB care. A total of 23 DR-TB patients were identified and their pathways to access DR-TB care were recorded using semi-structured interviews.

Results: The total DR-TB pathway time of new patients (who did not report any past episode of TB) (180 days; IQR 123,346) was found to be more than twice that of retreatment patients (who reported a past episode of TB) (69 days; IQR 42,128).

Conclusions: The unacceptable delay for diagnosis and treatment of DR-TB in Mumbai advocates for consistent implementation of early screening of patients using rapid gene-based technologies.
The effectiveness and safety of antifibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis
Authors: Ker Katharine , Prieto-Merino David , Sprigg Nikola , Mahmood Abda , Bath Philip , Kang Law Zhe , Flaherty Katie , Roberts Ian
Published: February 2018

Introduction: The Antifibrinolytic Trialists Collaboration aims to increase knowledge about the effectiveness and safety of antifibrinolytic treatment by conducting individual patient data (IPD) meta-analyses of randomised trials. This article presents the statistical analysis plan for an IPD meta-analysis of the effects of antifibrinolytics for acute intracranial haemorrhage.

Methods: The protocol for the IPD meta-analysis has been registered with PROSPERO (CRD42016052155). We will conduct an individual patient data meta-analysis of randomised controlled trials with 1000 patients or more assessing the effects of antifibrinolytics in acute intracranial haemorrhage. We will assess the effect on two co-primary outcomes: 1) Death in hospital within 30 days of randomisation, and 2) Death  or dependency at final follow-up within 90 days of randomisation. The co-primary outcomes will be limited to patients treated within three hours of injury or stroke onset. We will report treatment effects using odds ratios and 95% confidence intervals. We use logistic regression models to examine how the effect of antifibrinolytics vary by time to treatment, severity of intracranial bleeding, and age. We will also examine the effect of antifibrinolytics on secondary outcomes including death, dependency, vascular occlusive events, seizures, and neurological outcomes. Secondary outcomes will be assessed in all patients irrespective of time of treatment. All analyses will be conducted on an intention-to-treat basis.

Conclusions: This IPD meta-analysis will examine important clinical questions about the effects of antifibrinolytic treatment in patients with intracranial haemorrhage that cannot be answered using aggregate data. With IPD we can examine how effects vary by time to treatment, bleeding severity, and age, to gain better understanding of the balance of benefit and harms on which to base recommendations for practice.
МОТИВАЦИЯ ПРЕПОДАВАТЕЛЯ ВУЗА К ИСПОЛЬЗОВАНИЮ ЭЛЕКТРОННЫХ ОБРАЗОВАТЕЛЬНЫХ ТЕХНОЛОГИЙ В УЧЕБНОМ ПРОЦЕССЕ
Authors: Romanova Lyubov Leonidovna
Published: February 2018

В статье описываются проблемы развития дистанционного обучения в вузе, с которыми сталкивается администрация и профессорско-преподавательский состав образовательной организации. К проблемам, в частности относится проблема мотивации ППС вуза к созданию и применению электронных образовательных технологий. На примере ФГБОУ ВО Амурский государственный университет описаны меры, направленные на развитие дистанционной формы обучения в вузе. Автором проведен анализ психологической литературы по вопросам мотивации, как в целом, так и мотивации преподавателей вуза к применению дистанционного обучения. На основании модели, предложенной Н.В. Немовой, автором выделены ведущие мотивы  преподавателей вуза: мотив реализация себя в профессиональной деятельности как творче­ской личности, мотив личного развития, приобретения новой информации, мотив самоутверждения, достижения социального успеха, потребность быть в коллективе, мотив стабильности, защищенности, мотив состязательности.На основе анализа научной литературы предложены способы стимулирования мотивов, такие как: стимулирование высокого уровня самостоятельности преподавателя, отражающийся в возможности работать по интересующей программе; обеспечение преподавателям возможности прохождения повышения квалификации по организации дистанционных (электронных) образовательных технологий; предоставление возможности распространения опыта работы через проблемные конференции, педагогические чтения, семинары; вхождение в состав различных органов, занимающихся развитием дистанционного обучения в вузе; предоставление оплачиваемых часов на методическую работу; методическое сопровождение различных конкурсов в сфере реализации электронного обучения в вузе.Исследование отношения и мотивации деятельности преподавателей к применению дистанционного обучения в вузе необходимо для определения средств стимулирования их деятельности, которая способствует достижению наиболее качественного результата.
СОЦИОМЕТРИЧЕСКИЕ ИССЛЕДОВАНИЕ СВЯЗИ ПОНИМАНИЯ В ОБЩЕНИИ С КОГНИТИВНЫМИ СТИЛЯМИ ЧЛЕНОВ ГРУППЫ
Authors: Kadieva Roza Ismailovna , Aliomarov Limat Mirzahanovich , Rakhmetov Telman Suleimanovich
Published: February 2018

Статья посвящена анализу взаимопонимании в общении с когнитивными стилями членов группы и выявление связи между продуктивностью понимания людьми друг друга в общении и степенью их психологической дифференциации.Наше исследование состоит в том, что испытуемые – школьники в массе не дифференцируют такие стороны в человеке, как «способность понять, быть понятым» и «симпатичность, приятность».Таким образом, вследствие «эффекта ореола» приятные и симпатичные в общении люди выделяются в имплицитные теории наших испытуемых и положительными чертами по критерию «понимания».Приведенный эксперимент позволяет проводить дальнейший анализ влияния когнитивного стиля на понимание в общении. Достаточно хорошо дифференцируют испытуемые исследуемые сферы межличностных отношений и отличают критерий «понимание» от остальных использованных в социометрии критериев.
ПРОФЕССИОНАЛЬНЫЙ УСПЕХ В ПРЕДСТАВЛЕНИИ СТУДЕНТОВ-ПСИХОЛОГОВ С РАЗЛИЧНЫМИ ЦЕННОСТНО-МОТИВАЦИОННЫМИ ОСОБЕННОСТЯМИ
Authors: Belova Ekaterina Vladimirovna
Published: February 2018

В статье приводятся результаты теоретического анализа феномена успеха в психологии и эмпирического исследования содержания представлений о профессиональном успехе и отношения к нему в связи с профессиональной мотивацией, смысложизненными и ценностными ориентациями студентов-психологов. Во введении отмечается актуальность изучения студенческих представлений о профессиональном успехе в условиях вызовов современного российского общества. На основании обзора литературы делается вывод о том, что феномен успеха раскрывается в отношении к объективному достижению субъекта в конкретной деятельности и носит характер ценностно-смыслового образования. В исследовании приняли участие 90 студентов-психологов двух ростовских вузов. Применялись методы сочинения, контент-анализа, тестирования и математической статистики. Результаты проведенного исследования свидетельствуют о связи между содержательным и отношенческим компонентами представлений о профессиональном успехе. Обнаружена связь представлений о профессиональном успехе с преобладанием внутренней / внешней отрицательной профессиональной мотивации, со смысложизненными и ценностными ориентациями респондентов. Делается вывод о сложных внутренних отношениях между представлениями о профессиональном успехе, ценностями и профессиональной мотивацией личности.
HEALTHY LIFESTYLES IN HIGHER EDUCATION
Authors: Васенков Николай , Vasenkov Nikolay , Хабибуллин Илдар , Habibullin Ildar , Гусев Павел , Gusev Pavel
Published: February 2018

Physical health of students is tending to deteriorate. Educational organizations should be taken administrative measures to improve the process of adaptation of entrants to college life. Organisational measures taken by the administration of the University and the Department of physical education had a positive impact on students ' knowledge about the complex GTO. Significantly more students coped with the norms of the TRP and received marks of various denominations
Management of chronic oedema in patients with multiple morbidity
Authors: Todd Marie
Published: February 2018

Marie Todd, Lymphoedema Clinical Nurse Specialist, Specialist Lymphoedema Service, Glasgow, discusses the difficulties of caring for people with compounding conditions
Predicting and preventing alcohol relapse in alcohol-related liver disease
Authors: Ranasinghe Iyoni , Sin Jacqueline , Norman Ian , Lau-Walker Margaret
Published: February 2018

Background:

despite a 450% increase in UK alcohol-related liver disease mortality over the past 30 years, little evidence-based guidance exists regarding preventing recidivism post-liver transplant for alcohol-related liver disease.

Method:

a systematic literature review was conducted to identify demographic variables predictive of alcohol relapse and effective psychosocial interventions for alcohol-related liver disease patients post-liver transplant.

Results:

variables most significantly predictive of alcohol relapse post-transplant were—less than 12 months pre-liver transplant abstinence; patients with children; poor pre-liver transplant psychosomatic evaluation; non-compliance with post-liver transplant treatment plan; and patients with active insurance policies. Structured management was the most effective psychosocial intervention in preventing alcohol relapse.

Conclusion:

findings should be interpreted cautiously, due to limited and poor-quality evidence. Rigorously designed further research of the psychosocial interventions targeting predictive demographic variables is recommended.
Factors that influence nurses' assessment of patient acuity and response to acute deterioration
Authors: Dalton Mark , Harrison John , Malin Anitra , Leavey Conan
Published: February 2018

Background:

nurses play a crucial role in the early recognition and management of the deteriorating patient. They are responsible for the care they provide to their patients, part of which is the monitoring of vital signs (blood pressure, pulse, respiratory rate and temperature), which are fundamental in the surveillance of deterioration. The aim of this study was to discover what factors influence how nurses assess patient acuity and their response to acute deterioration.

Methods:

a generic qualitative approach was used. Some 10 nurses working in an acute NHS trust were interviewed using a semi- structured approach, with equal representation from medical and surgical inpatient wards.

Results:

the main themes identified were collegial relationships, intuition, and interpretation of the MEWS system (Modified Early Warning Score). Collegial relationships with the medical staff had some influence on the nurses' assessment, as they tended to accept the medical peers' assessment as absolute, rather than their own assessment. It was also highlighted that nurses relied on the numerical escalation of the MEWS system to identify the deteriorating patient, instead of their own clinical judgement of the situation. Interestingly, the nurses found no difficulty in escalating the patient's care to medical staff when the patient presented with a high MEWS score. The difficulty arose when the MEWS score was low—the participants found it challenging to authenticate their findings.

Conclusion:

this study has identified several confounding factors that influence the ways in which nurses assess patient acuity and their response to acute deterioration. The information provides a crucial step forward in identifying strategies to develop further training.
The provision of ambulatory systemic anti-cancer therapy
Authors: Cooper Susan , de Lord Kate
Published: February 2018

This article reflects on the changing nature of the provision of care and delivery of ambulatory systemic anti-cancer therapy (SACT) services. It reviews the national guidance and looks at ambulatory SACT in terms of patients being treated closer to home, i.e. ambulatory care in its truest sense. It considers the impact on quality of life for patients receiving treatments at a place of their choice. It explores the role of the nurse as an advanced practitioner while also examining the safety and delivery of complex regimens ensuring robust pathways are in place to deliver care in a safe and standardised way.
Continuous, comprehensive and crucial care: The role of the CNS in the metastatic castration-resistant prostate cancer patient pathway
Authors: Basketter Vanessa , Benney Miranda , Causer Louise , Fleure Louisa , Hames David , Jones Sarah , Patel Kamlesh , White Lisa
Published: February 2018

Several treatment options are now available to men with metastatic castration-resistant prostate cancer (mCRPC). While survival rates for mCRPC continue to improve, patients are faced with increasingly complex treatment pathways and decisions. The clinical nurse specialist (CNS) plays a crucial role in navigating patients with mCRPC through their treatment pathway and fulfils a number of key responsibilities, including providing holistic care and support to patients and their families, educating and communicating with them in a timely and effective manner, and liaising with other healthcare professionals to seamlessly coordinate patient treatment. However, increasing patient caseloads and administrative duties are leaving CNSs with little time to fulfil their supportive role. Additional resources are needed in order to both promote and preserve this supportive role, thus ensuring that mCRPC patients receive the best possible care.
A specialist mental health service that places the mother–infant relationship at the centre of care
Authors: Goldsmith Joanna , Goldberger Danny , Taylor Catherine , Melbourne Jane
Published: February 2018

This article describes an established and developing parent-infant mental health service in Surrey that integrates health visitors and psychotherapists to work with mothers at risk of, and identified as, having mental health difficulties. Tracing the work from referral through to therapeutic input, the authors highlight the benefits of what is termed a ‘containing’ relationship with parents and infants and, specifically, the use of therapeutic baby massage. Two case studies focus on the therapeutic work and, in particular, the importance of the therapeutic relationship as part of the intervention and its positive outcomes.
A critical review of listening visits in women with postnatal depression
Authors: Willis Angela
Published: February 2018

This review explores national guidelines, and women's and health visitors' views on providing listening visits to women with mild-to-moderate postnatal depression. Antidepressants can provide quick relief for symptoms, but many women are reluctant to use medication due to potential side-effects and the impact on breastfeeding. Listening visits are often preferred by women, especially when delivered by an empathetic and intently listening health visitor. Listening visits also provide additional support for women who decline antidepressants, especially in areas with long mental health waiting lists. However, health visitors often feel ill equipped to provide listening visits in practice unless they have undertaken additional training. Guidelines and availability of providing listening visits also varies between clinical commissioning groups, which needs to be addressed.
O poder disciplinar enquanto dimensão da cultura organizacional: um estudo multicasos em instituições de ensino superior privadas
Authors: Teixeira da Silva André Maurício , Lourenço Mariane Lemos
Published: February 2018

Este artigo teve como objetivo geral investigar como se manifesta e é interpretado, pelos docentes, o poder disciplinar em face dos elementos da cultura organizacional em instituições de ensino superior (IES) privadas. Foi realizado um estudo multicasos, em IES privadas na região Sul do Brasil, pelo qual se priorizou a análise do discurso organizacional no estabelecimento dos conceitos, dos objetos e na posição dos sujeitos nesse discurso e das suas ações com relação às práticas de produção, transmissão e consumo de textos que reforcem, alterem ou resistam ao discurso. Destacou-se, dentre os achados, a precarização do trabalho docente nesse contexto, em que o professor passa a ser um mero executor de programas de ensino com reduzida autonomia e controle das suas atividades. Aliado a isso, ainda, passa a incorporar as atividades de promoção e manutenção das instituições com o intuito de agradar os clientes e o mercado de atuação. Tudo isso realizado sob estrita vigilância e controle por parte das instituições e dos alunos. Este trabalho contribui no sentido de elucidar a situação dos professores no Ensino Superior privado, pois fornece uma compreensão a partir das suas próprias interpretações e experiências.
Desafios na formação de profissionais em Administração no Brasil
Authors: Boaventura Patrícia Silva Monteiro , Souza Lucas Lopes Ferreira de , Gerhard Felipe , Brito Eliane Pereira Zamith
Published: February 2018

Apesar do crescimento no número de cursos de administração ao longo dos últimos anos, pesquisas mostram que o Brasil possui um dos piores indicadores de desempenho organizacional do mundo; e a formação profissional dos gestores nacionais pode ser apontada como uma das causas desse baixo rendimento, em especial, se considerar a relevância da gestão para o desempenho das empresas. Neste cenário, esta pesquisa teve como objetivo analisar o currículo de formação em administração de universidades do Brasil, bem como as competências trabalhadas pelos cursos e compará-las com a formação de escolas dos EUA. Para tal, foi realizado um estudo de caráter tanto qualitativo como quantitativo, assim, levantando-se dados de cursos de administração do Brasil e dos EUA. Para assegurar a autenticidade dos resultados, foi realizada triangulação de dados de diferentes fontes. Os resultados revelaram que, conquanto o modelo pedagógico americano tenha servido de base para a formatação dos cursos nacionais na década de 1940, as escolas brasileiras parecem não ter acompanhando o seu ritmo de mudança, promovendo uma reprodução técnica e instrumental desassociada da formação de pensadores críticos e criativos. Ademais, adaptações à realidade socioeconômica do contexto local parecem não ter sido avaliadas profundamente desde a criação do currículo mínimo em 1993.
Reflexão a respeito das contribuições e limites da história de vida na pesquisa em Administração
Authors: Godoy Arilda Schmidt
Published: February 2018

Este ensaio apresenta a modalidade de pesquisa denominada história de vida, com tal intuito, realçando alguns de seus limites e contribuições para a pesquisa em administração. Para alcançar este objetivo, o texto inicia com um breve registro das origens desse método investigativo, transcreve sua conceituação e ressalta suas contribuições fundamentais. Elenca autores que analisam tais contribuições no campo específico da investigação em administração e indica os temas mais explorados pela história de vida, nos estudos realizados em âmbito internacional e nacional. A seguir, são tratados alguns aspectos que limitam o processo analítico-interpretativo que caracteriza essa modalidade de pesquisa em administração. Para fechar o texto foi importante pontuar que a pesquisa que traz “novas cores e sabores” nem sempre tem sido valorizada na administração. No caso da história da vida, ressalta-se que esse método investigativo pode promover o esforço de autorreflexão do pesquisador de forma que ele tenha a oportunidade de transformar, recontextualizar e amplificar seus conhecimentos, com isso, podendo alterar sua visão a respeito do mundo e do seu próprio trabalho. O ensaio retrata o olhar da autora, a partir do qual se almeja suscitar indagações que levem a um diálogo frutífero quanto à possibilidade de ampliar a obtenção do conhecimento em administração.
Using Expansive Framing to Enhance Personal Relevancy and Engagement in Science
Authors: Radloff Jeffrey Daniel , Chase Anthony
Published: February 2018

Indiana science standards conceptualize science, engineering, and computer science towards two main goals: preparing students with adequate knowledge and skills to pursue science careers, and helping students develop into scientifically literate citizens capable of fully engaging with socio-scientific issues. Meeting these goals requires an understanding of how to contextualize science skills and content for application outside the classroom: teaching beyond the test towards students' future needs and interests. They need to make connections between science taught in the classroom with their own lives. One strategy for doing so is by utilizing expansive framing, a way of making this connection more tangible towards increasing relevancy and engagement with science. Here, we discuss expansive framing, how it works, and how it can be easily utilized in the K-12 science classroom. We follow up with considerations and implications for effective science teaching and learning.
The Ideological Study of Judicials From The Formal Centralistis to The Legal Pluralism (Analysis of the Meaning of Judge on Article 5 paragraph (1) of Law Number 48 Year 2009 on Judicial Power)
Authors: Yulianti Rina , Ikhwan Mufarrijul
Published: February 2018

Article 5 (1) of Law Number 48 Year 2009 concerning Judicial Power becomes ineffective if acentralistic ideology still working  in view of the judge. The type of study used in this researchwas a non-doctrinal legal studies (sociolegal research). Research conducted in the DistrictCourt and Religious Court in Madura based on the judges perception by meaning of article 5paragraph (1) law 48/2009 and justices consideration to verdict making process. The resultsshowing the judges majority interpret the Article 5, paragraph 1 Law 28/2009 to legaldiscovery (rechtsvinding) as an efforts if a legal vacuum, otherwise the judges did notinterpret used living law when there are legal gaps. Thus showing domination of the state lawover the law that lives in society. DOI: 10.15408/jch.v5i2.4190
Effort of Medan Mayor in Realizing Clean Government (Study About the Practice of Administration in Medan City To Prevent and Acts Criminal Actors of Corruption)
Authors: Sibarani Sabungan
Published: February 2018

The efforts of Mayor of Medan in creating a clean government in Medan City Government isto promote the rules and policies that have made the central government and implementedby the city government of Medan conditions include (a) the fact Integrity, (b) e-purchasing,(c) e-government, (d) reward (reward) and punishment (punishment), (e) unqualified (WTP)and the Procurement Services Unit (ULP). The role of the Mayor of Medan to prevent andtake action against perpetrators of corruption in the city government of Medan are (a) facingthe principle of transparency in carrying out the functions and duties of office to preventcorrupt practices, (b) make an early warning program of prevention of corruption, (c) andnine steps to eradicate corruption. That support wider community both from the communityorganizations, businesses, and students are needed. DOI: 10.15408/jch.v5i2.4952
The Elimination of Constitutional Court's Authority in The Dispute Case of General Election of Regional Head (Analysis of Decision of the Constitutional Court Number 97/PUU-XI/2013)
Authors: Chairnosia Jentel
Published: February 2018

The enactment of Law Number 32 Year 2004 is a manifestation of the development ofadvanced democracy, namely all local chief elected directly by the people except the positionof the Governor of Yogyakarta. However, in its development, the implementation of theGeneral Elections of Regional Head gave rise to dissatisfaction which resulted in the appealof the results of the General Election to the court for various reasons. The presence of theConstitutional Court as an institution that resolved the dispute over the General Election ofRegional Heads has not been able to provide justice to the public, especially the emergenceof many Constitutional Court rulings that cause debate. In its development, the ConstitutionalCourt abolished its authority in the settlement of disputes in the General Election of RegionalHeads as stipulated in Decision Number 97 / PUU-XI / 2013. The Constitutional Court is ofthe opinion that the Constitutional Court only has the authority to resolve election disputes ofDPR, DPD, President/Vice President because the election is done nationally, while theelection is conducted in certain areas only. In addition, the volume of incoming cases relatedto election disputes more than the law review case which is the main authority of theConstitutional Court, so that this can affect the quality of the decisions of the ConstitutionalCourt considering the dispute resolution of the results of the General Election should beterminated within fourteen days. DOI: 10.15408/jch.v5i2.7090
Šabac
Authors: Kador Thomas , Lukic Vesna
Published: February 2018

Drawn from a longstanding collaboration between the authors, this contribution explores the common ground between filmmaking and archaeological investigation and in particular a shared interest in haptic experiences and the material properties of the world. This leads us to propose the use of the camera and the moving image it produces as valuable archaeological research tools. To illustrate this we present both a short film and brief discussion paper focusing on the Serbian town of Šabac as a Holocaust landscape and its link with a group of Jewish refugees known as the “Kladovo transport”. Based on this case study we aim to highlight the transformative potential of artistic interventions in archaeological questions, and indeed vice versa, to construct new modes of knowing.
Thinking Place
Authors: Bevan Elizabeth Anne , Downes Jane
Published: February 2018

Wilder Being was a participatory art and archaeology project that aimed to set an understanding of coastal erosion of archaeological heritage within wider contexts of climate change and sustainability. Sub-titled Creation and destruction in the littoral zone, Wilder Being took place at an archaeological site on the shores of the island of Sanday in Orkney. Our place-based event explored, using art and archaeology techniques and narrative, this site of coastal erosion as a creative resource. The interdisciplinary collaboration highlighted the connectivity between arts, humanities and sciences as it highlighted the blurring of lines between land and sea, culture and nature. In this paper we reflect on the context and outcomes of Wilder Being project, how it has contributed to the dialogue around participatory and relational approaches to archaeology, and how we might re-think sites threatened by coastal erosion sites as sites for creative dialogue.
Editorial
Authors: Costa Lucia De Fátima Lúcio Gomes da
Published: February 2018

Caros leitores,

É com satisfação que apresentamos o primeiro volume de 2017 da Revista Brasileira de Gestão, Negócio e Tecnologia da Informação - EmpíricaBR. Nesta edição, são apresentados seis artigos. O primeiro deles tem o título: “Lei Maria da Penha: um estudo dos índices de homicídios de mulheres no Brasil na década 2003-2013” e discute aspectos relativos às políticas públicas de gênero. Ainda sobre políticas públicas, o segundo título “Política pública de reforma agrária: um estudo de caso no RN na perspectiva da função social da terra” trata sobre as questões de reforma agrária. O terceiro título: “Análise do processo de reestruturação do setor elétrico brasileiro” discorre sobre aspectos de recursos estratégicos para nossa economia. Na mesma perspectiva, o artigo “Comércio internacional e desenvolvimento socioeconômico: o polo industrial de Goianinha e a utilização de gás natural” aborda fatores estratégicos no conceito de “clusters”. Sobre empreendedorismo foi estudado o papel das incubadoras, por meio do texto “Importância de incubadoras de empresas em ambiente acadêmico: um estudo do perfil empreendedor dos discentes”. Por último, o texto: “Comprometimento organizacional: um estudo comparativo entre docentes e servidores do IFRN-Campus Nova Cruz” traz um estudo de caso sobre a temática de comprometimento organizacional.

Assim, fazemos o convite à leitura desses textos que apresentam contribuições importantes sobre aspectos estratégicos do empreendedorismo e negócios e na gestão pública.

Boa leitura.
Oral Health-Related Outcomes in Edentulous Patients Treated With Mandibular Implant-Retained Dentures Versus Complete Dentures: Systematic Review With Meta-Analyses
Authors: Kroll Philip , Hou Lisa , Radaideh Hani , Sharifi Nazanin , Han Phuu P. , Mulligan Roseann , Enciso Reyes
Published: February 2018

The objective of this systematic review was to determine the effect on oral health-related outcomes from mandibular implant-retained dentures opposing maxillary complete dentures in edentulous middle-age and older adults, compared with complete removable dentures in both arches. Randomized controlled trials included participants with an average age of 65 years or older. The Cochrane Library, MEDLINE, and Web of Science were searched. A total of 228 abstracts were reviewed for inclusion criteria, with 14 trials included and analyzed for risk of bias. Eleven of these studies were assessed as being at an unclear risk of bias, and 3 were at high risk. Mandibular implant-retained overdenture therapy showed statistically significant improvements in the patients' general satisfaction (P = .003), oral health-related quality of life (P < .001), and chewing ability (P < .001), over the patients with complete dentures. There were no significant differences in the percentage of patients who were satisfied with their overdentures vs complete dentures for comfort, retention, esthetics, or chewing ability; however, only 2 studies reported these outcomes. In terms of nutritional status 1 year after treatment, vitamin B12 blood levels increased significantly in the implant-retained group (P = .003), but not the other nutritional values. Implant-retained mandibular overdentures are an option for middle-aged and elderly edentulous patients as they significantly improve some of the outcomes; however, the quality of the evidence was moderate/low, due to the small number of studies included and the risk of bias. Future research should include objective outcomes such as masticatory performance, chewing efficacy, and muscular coordination.
Comparison of the Use of Titanium–Zirconium Alloy and Titanium Alloy in Dental Implants: A Systematic Review and Meta-Analysis
Authors: Cruz Ronaldo Silva , Lemos Cleidiel Aparecido Araujo , Oliveira Hiskell Francine Fernandes , de Souza Batista Victor Eduardo , Pellizzer Eduardo Piza , Verri Fellippo Ramos
Published: February 2018

The aim of this study was to compare the values of bone-implant contact (BIC) and removal torque (RTQ) reported in different animal studies for titanium–zirconium (TiZr) and titanium (Ti) dental implants. This review has been registered at PROSPERO under number CRD42016047745. We undertook an electronic search for data published up until November 2017 using the PubMed/Medline, Embase, and The Cochrane Library databases. Eligibility criteria included in vivo studies, comparisons between Ti and TiZr implants in the same study, and studies published in English that evaluated BIC and RTQ. After inclusion criteria, 8 studies were assessed for eligibility. Of the 8 studies, 7 analyzed BIC outcome and 3 analyzed RTQ outcome. Among such studies, 6 studies were considered for meta-analysis of quantitative for BIC and 2 studies for RTQ. There was no significant difference for BIC analysis (P = .89; random ration [RR]: −0.21; 95% confidence interval [CI]: −3.14 to 2.72). The heterogeneity of the primary outcome studies was considered low (7.19; P = .21; I2: 30%). However, the RTQ analysis showed different results favoring the TiZr dental implants (P = .001; RR: 23.62; 95%CI: 9.15 to 38.10). Low heterogeneity was observed for RTQ (χ2: 1.25; P = .26; I2: 20%). Within the limitations of this study, there was no difference between TiZr and Ti alloys implants in terms of BIC. However, TiZr implants had higher RTQ than Ti alloys.
SOURCES OF RESISTANCE TO Fusarium oxysporum f. sp.cubense IN BANANA GERMPLASM
Authors: Ribeiro Lindinéia Rios , Silva Sebastião de Oliveira e , Oliveira Saulo Alves Santos de , Amorim Edson Perito , Serejo Janay Almeida Santos , Haddad Fernando
Published: February 2018

ABSTRACT Fusarium wilt (syn= Panama disease), caused by Fusarium oxysporum f. sp. cubense (FOC), is one of the most destructive diseases of banana, being genetic resistance the main management strategy for this disease. Since the pathogen is constantly evolving to supplant the genetic resistance, new sources of resistance must be investigated by genetic improvement programs aiming to developing new varieties. The objective of the present study was to identify sources of resistance from the different accessions maintained in the banana active germplasm bank (BAGB) at Embrapa Mandioca e Fruticultura. Forty-one BAGB accessions were evaluated, including 17 diploids, 21 triploids, and two tetraploids. The area under the disease progress curve, disease index, and incubation period were also evaluated. In relation to FOC resistance, there is genetic variability available among the BAGB accessions. The genotype M53 is notable for the complete resistance it expressed, and the accessions Birmanie, PA Songkla, Pirua, Imperial, Poyo, Ambei, Walebo, and Kongo FRF 1286 expressed quantitative resistance.
Water potential in peach branches as a function of soil water storage and evaporative demand of the atmosphere
Authors: Monteiro Alex Becker , Reisser Júnior Carlos , Romano Luciano Recart , Timm Luís Carlos , Toebe Marcos
Published: February 2018

Abstract The use of water potential indicators in the plant has been adopted in irrigation management, in recent years, since it is accepted that the plant is the best indicator of its own water status. The objective of this study was to verify the relationship between water potential in peach tree branches and the evaporative demand of the atmosphere and the water availability in two textural classes of an Aquertic Hapludalf soil, aiming to adopt irrigation management strategies based on the water potential in the plant. Research was carried out in a commercial peach orchard, cv. Esmeralda, in the municipality of Morro Redondo-Rio Grande do Sul state, Brazil. Four peach tree rows were evaluated, being two irrigated and two non irrigated. The irrigation management was based on the replacement of the potential crop evapotranspiration. It was concluded that the water potential in the peach tree branch is positively related with the evaporative demand of the atmosphere and negatively related with soil water storage. Future studies should adopt irrigation management strategies for peach trees based on the water potential mainly for the irrigation management of post-harvest peach trees.
Splenic implant preservation after conservation in lactated Ringer´s solution
Authors: MATOS FILHO ARGOS SOARES DE , PETROIANU ANDY , CARDOSO VALBERT NASCIMENTO , VIDIGAL PAULA VIEIRA TEIXEIRA
Published: February 2018

ABSTRACT Objective: to evaluate the morphology and function of autogenous splenic tissue implanted in the greater omentum, 24 hours after storage in Ringer-lactate solution. Methods: we divided 35 male rats into seven groups (n=5): Group 1: no splenectomy; Group 2: total splenectomy without implant; Group 3: total splenectomy and immediate autogenous implant; Group 4: total splenectomy, preservation of the spleen in Ringer-lactate at room temperature, then sliced and implanted; Group 5: total splenectomy, spleen sliced and preserved in Ringer-lactate at room temperature before implantation; Group 6: total splenectomy with preservation of the spleen in Ringer-lactate at 4°C and then sliced and implanted; Group 7: total splenectomy and the spleen sliced for preservation in Ringer-lactate at 4°C before implantation. After 90 days, we performed scintigraphic studies with Tc99m-colloidal tin (liver, lung, spleen or implant and clot), haematological exams (erythrogram, leucometry, platelets), biochemical dosages (protein electrophoresis) and anatomopathological studies. Results: regeneration of autogenous splenic implants occurred in the animals of the groups with preservation of the spleen at 4ºC. The uptake of colloidal tin was higher in groups 1, 3, 6 and 7 compared with the others. There was no difference in hematimetric values in the seven groups. Protein electrophoresis showed a decrease in the gamma fraction in the group of splenectomized animals in relation to the operated groups. Conclusion: the splenic tissue preserved in Ringer-lactate solution at 4ºC maintains its morphological structure and allows functional recovery after being implanted on the greater omentum.
Efeito da Estratégia Saúde da Família nas internações por condições sensíveis à atenção primária em menores de um ano na Bahia, Brasil
Authors: Pinto Junior Elzo Pereira , Aquino Rosana , Medina Maria Guadalupe , Silva Marcelo Gurgel Carlos da
Published: February 2018

O estudo teve como objetivo avaliar o efeito da expansão da cobertura da Estratégia Saúde da Família (ESF) sobre as internações por condições sensíveis à atenção primária (ICSAP) em crianças menores de um ano. Trata-se de um estudo ecológico longitudinal com uso de painel de dados, cujas unidades de análise foram os 417 municípios da Bahia, Brasil, entre 2000 a 2012. Os dados foram obtidos dos sistemas de informação em saúde. A taxa de ICSAP foi o desfecho e a cobertura da ESF à exposição principal. As covariáveis eram referentes às características demográficas e socioeconômicas e disponibilidade de leitos pediátricos nos municípios. Foi realizada análise de regressão bivariada e multivariada para painel de dados, com resposta binomial negativa e modelos de efeitos fixos, utilizando como medida de associação o risco relativo (RR), bruto e ajustado, com seus respectivos intervalos de confiança. Para controle de efeito de tendência, os modelos foram ajustados pelo tempo. Entre 2000 e 2012, 248.944 ICSAP foram registradas em crianças menores de um ano, e a mediana das taxas municipais de ICSAP reduziu 52,5% no período, variando de 96,9 para 46,0 hospitalizações evitáveis por mil nascidos vivos. Após o ajuste do modelo, a redução das internações evitáveis se manteve nos diferentes níveis de cobertura da ESF. Este estudo demonstrou os efeitos da consolidação da ESF nas ICSAP em menores de um ano, o que indica a importância do fortalecimento das ações no âmbito da atenção primária, com o intuito de oferecer assistência resolutiva ao primeiro contato e evitar hospitalizações desnecessárias.
Integração da atenção básica à rede assistencial: análise de componentes da avaliação externa do PMAQ-AB
Authors: Chaves Lenir Aparecida , Jorge Alzira de Oliveira , Cherchiglia Mariangela Leal , Reis Ilka Afonso , Santos Marcos Antônio da Cunha , Santos Alaneir de Fátima , Machado Antônio Thomaz Gonzaga da Matta , Andrade Eli Iola Gurgel
Published: February 2018

Estudo transversal que avalia a integração entre a atenção básica e a rede assistencial do Sistema Único de Saúde (SUS), por meio do Modelo de Resposta Gradual da Teoria de Resposta ao Item. Com base nos dados de 17.202 equipes que participaram do Programa Nacional de Melhoria do Acesso e da Qualidade da Atenção Básica (PMAQ-AB), 2012, foram mensurados gradientes de integração para identificar o perfil das equipes por nível de integração. Os resultados demonstram que os itens referentes às ações de apoio matricial - consultas médicas; discussão de caso; ação clínica compartilhada; construção conjunta de projetos terapêuticos; atividade de educação permanente; discussão processo trabalho; intervenções no território e realização de visita com profissionais de atenção básica - melhoram o desempenho das equipes de atenção básica. Dispositivos de comunicação entre as equipes reforçam esse entendimento. Contudo, a frequência em torno de 50% de respostas associadas ao pior cenário para alguns itens do estudo, evidenciou a necessidade de qualificação da integração entre as ações de atenção básica e especializada para a consolidação de uma atenção primária à saúde abrangente.