bluuebunny/crossref_metadata_2025 huggingface dataset:
Characteristics And Causes of Work-Related Eye Trauma at Bekasi Regency Hospital
Authors: Anugrah Andreas Surya , Ruhdiat Rudi , Wadan Angelicha Magdalena Slomen Kewa , Abrar Ligadhea
Published: February 2025

Work-related eye trauma cases at Bekasi Regency Hospital were analyzed in a retrospective descriptive study using secondary data from medical records over five years (2020–2024). A total of 66 subjects were studied, with the majority being male (78.8%, n = 52) and an average age of 28.1 ± 6.5 years (range: 15–54). The largest age group was 15–34 years (47%, n = 31). Most patients were self-employed in machinery, metalwork, trade, and agriculture (45.5%, n = 30). The most common eye trauma was injury to the eyelid and adnexa (18.8%, n = 19), followed by open laceration or penetrating trauma of the eyeball (27.3%, n = 18). The primary mechanism of injury was impact by blunt or sharp objects (53%, n = 35), followed by puncture wounds from sharp objects during activities like nailing (10.6%, n = 7) and exposure to cleaning or maintenance equipment (10.6%, n = 7). Other causes included cutting activities (6.1%, n = 4), welding (6.1%, n = 4), and exposure to chemicals (4.5%, n = 3). Visual impairment was reported in most cases (66.7%, n = 44), and the same percentage required surgical intervention. Urgent measures are needed to improve awareness of workplace eye safety and implement effective prevention strategies. Occupational safety programs should include specific training on eye protection and educational campaigns to enhance workers’ understanding of risks and preventive measures for work-related eye trauma.
Proposta de Sistema de Remuneração para Contratos de Gestão com Organizações Sociais de Saúde
Authors: Pollini Marcelo
Published: February 2025

Objetivo: Desenvolver um modelo de remuneração para contratos de gestão com Organizações Sociais de Saúde (OSS) no estado de São Paulo, integrando produção, custos fixos e mecanismos de remuneração variável. Método: Estudo de abordagem qualitativa, com análise documental de contratos de gestão, convênios e termos de colaboração relacionados às OSS no Brasil. O modelo se estrutura em cinco componentes principais: produção baseada na tabela SUS Paulista, custeio de despesas fixas, incentivos financeiros ligados à qualidade, eficiência operacional medida por Grupos de Diagnósticos Relacionados (DRG), e governança regionalizada. Resultados: O modelo propõe: remuneração baseada em produção, alinhada à tabela SUS Paulista; parcela fixa para custos administrativos e operacionais; incentivos para atuação regionalizada com Sistemas de Gestão Integrados (SIGs); incentivos financeiros vinculados a indicadores de qualidade; e incentivos à eficiência operacional. Conclusão: O modelo promove previsibilidade financeira, incentiva eficiência e qualidade e alinha as metas institucionais das OSS aos objetivos estratégicos do Sistema Único de Saúde (SUS), incluindo a integração regional.
Transformando las estrategias docentes y el aprendizaje personalizado en la educación superior a través de la inteligencia artificial
Authors: Cuenca Masache Diana Teresa , Chiza López Diego Fernando , Ramírez Maza Arturo , Alvarado Ortiz Juan de Jesús
Published: February 2025

La inteligencia artificial (IA) se ha consolidado como un recurso clave en la evolución de la educación superior, facilitando la personalización del aprendizaje y optimizando los procesos educativos. Herramientas como los tutores virtuales y los algoritmos de aprendizaje adaptativo están transformando el papel de los docentes y la dinámica en las aulas, promoviendo un modelo educativo centrado en el estudiante. La adopción de tecnologías avanzadas abre nuevas oportunidades para mejorar la calidad educativa y garantizar un acceso más equitativo al conocimiento. Sin embargo, su integración plantea desafíos como la capacitación docente, la adaptación de los programas académicos y la evaluación de su impacto en el aprendizaje. A pesar de estos retos, la IA se presenta como una alternativa innovadora para ajustar las experiencias de aprendizaje a las necesidades individuales, aunque su implementación efectiva requiere una reconfiguración de las estrategias pedagógicas y la infraestructura tecnológica en las instituciones académicas.
EVALUATING THE EFFECTIVENESS OF THE GURU PENGGERAK PROGRAM: A GUIDANCE AND COUNSELING APPROACH TO TEACHER PROFESSIONAL DEVELOPMENT AND EDUCATIONAL TRANSFORMATION
Authors: Abdillah Arif Taufiq Dani , Setianingsig Eka Sari
Published: February 2025

Evaluation is one of the methods used to assess the success of a process in achieving its initial objectives. Evaluation through a guidance and counseling approach involves the collection of information (data) to determine effectiveness (implementation and achievement) based on three evaluation components: Understanding, Conform, and Action (UCA). This approach is applied in evaluating the Program Pendidikan Guru Penggerak (PPGP) in Banten Province by the Balai Guru Penggerak (BGP) Banten, using an evaluation mechanism that aligns with the principles of Guidance and Counseling (BK). The evaluation results serve as a benchmark for the success of the Guru Penggerak Program (PGP). The findings of this study indicate that the application of evaluation using the guidance and counseling approach in the implementation of the Guru Penggerak Program is more easily applicable. By utilizing the three evaluation components, the level of satisfaction regarding the program’s implementation and outcomes, the competencies acquired, as well as the planned actions and decision-making processes of Guru Penggerak participants, can be effectively identified.
IMPEMENTASI ALAT ZERO EMISSION SMOKER DALAM RANGKA PROGRAM INOVILLAGE KEPADA UMKM IKAN SALAI RIZKI 99 DI DESA SUNGAI KEDUKAN, KECAMATAN RAMBUTAN, KABUPATEN BANYUASIN 1, SUMATERA SELATAN.
Authors: Pratiwi Indah , Pamungkas Bimo , Apriyanti Tria , Firdausi Mohammad Ridwan , Rusnandi Irawan , Trisnaliani Letty , Yunanto Isnandar
Published: February 2025

Sumatera Selatan terkenal dengan kekayaan akan sumber daya perairan, khususnya ikan. Hal ini menjadi kemudahan bagia masyarakat dalam meningkatkan ekonomi tetapi juga dapat menadi tantangan dalam menjaga kualitas produk perikanan. Data dari Badan Pusat Statistik Provinsi Sumatera Selatan menunjukkan bahwa produksi budidaya ikan antara tahun 2020 hingga 2022 mencapai 357.138 ton. Namun, ikan sebagai bahan pangan yang mudah rusak memerlukan penanganan khusus untuk mempertahankan kualitasnya. Metode pengolahan seperti pembekuan dan pengeringan sering terhambat oleh ketergantungan pada sinar matahari, sehingga pengasapan menjadi alternatif yang populer, terutama di Desa Sungai Kedukan, Kecamatan Rambutan, Kabupaten Banyuasin 1. Di desa ini, Ikan Salai Rizki 99 telah beroperasi selama 45 tahun dan menjadi salah satu produsen ikan salai terkemuka, meskipun menghadapi masalah dalam fasilitas produksi dan sistem pengasapan yang masih terbuka. Dengan permintaan pasar yang tinggi, produksi harian mencapai 120-150 kg, sementara permintaan mencapai 170-230 kg. Untuk mengatasi masalah ini, inovasi teknologi berupa Zero Emission Smoker diperkenalkan, yang memanfaatkan energi terbarukan dan proses pirolisis untuk mengurangi emisi dan meningkatkan efisiensi produksi. Alat ini tidak hanya mempercepat waktu pengasapan dari 24 jam menjadi 12 jam, tetapi juga meningkatkan kapasitas produksi dan pendapatan. Dengan desain yang ramah lingkungan, Zero Emission Smoker diharapkan dapat mendukung keberlanjutan industri perikanan di Sumatera Selatan, sejalan dengan tujuan pembangunan berkelanjutan.
Purslane (Portulaca oleracea) - nutritional value and food uses
Authors:   Department of Food Science, University of Life Sciences “King Mihai I” from Timişoara, Calea Aradului 119, 300645 –Timişoara, Romania, Mitroi Cristina L.
Published: February 2025

Throughout history, humanity has used approximately 7000 plant species for food, fodder, medicine, clothing, and shelter, but only about 200 species are used today. Portulaca oleracea is one of the most common eight plants worldwide and can thrive in various environments, including flower beds, cornfields, and waste areas. It is mainly used in green salads and vegetable juices. It can be used to treat burns, headaches and diseases associated with the intestine, liver, stomach, cough, breathing difficulties and arthritis. It has important applications in herbal medicine as a laxative, cardiac stimulant, muscle relaxant, and anti-inflammatory and diuretic treatment. Purslane is recognized as a valuable source of nutraceutical compounds such as omega-3 fatty acids, vitamins A and E, essential amino acids, and polyphenols, all of which have a positive impact on human health and nutrition.
Physicochemical and sensory characterization of vegetable fat pressed cheese
Authors:   Faculty of Food Engineering, University of Life Sciences ”King Mihai I” from Timișoara, Calea Aradului 119A, 300645 – Timișoara, România, Mocan Alexandra Maria , Cârlea Iulia ,   Faculty of Food Engineering, University of Life Sciences ”King Mihai I” from Timișoara, Calea Aradului 119A, 300645 – Timișoara, România, Velciov Ariana Bianca ,   Faculty of Food Engineering, University of Life Sciences ”King Mihai I” from Timișoara, Calea Aradului 119A, 300645 – Timișoara, România, Rădulescu Laura ,   Faculty of Food Engineering, University of Life Sciences ”King Mihai I” from Timișoara, Calea Aradului 119A, 300645 – Timișoara, România
Published: February 2025

At the basis of this experimental study is the process of obtaining vegetable fat pressed cheese and the physicochemical and sensory characterization of this product. The vegetable fat pressed cheese belongs to the category of scalded cheeses, created by partial or total replacement of animal fats in milk with vegetable fats. Thus, a more affordable product was obtained from a financial point of view, due to the low costs of vegetable fats, compared to animal fats. The non-hydrogenated palm oil used contributes to the texture and stability of the product, ensures the semi-hard consistency and uniform melting of the cheese. The cheese samples were analyzed from a sensorial and physicochemical point of view (determination of moisture, fat content, sodium chloride content and acidity) at different ripening time intervals, following the characteristics and their inclusion in the parameters of standard quality for cheeses
Research on the influence of horseradish addition on the properties of cream cheese
Authors:   Technical University of Cluj-Napoca, North Universitary Center of Baia Mare, Faculty of Sciences, Department of Chemistry and Biology, 76 Victoriei Street, 430122 Baia Mare, Romania;, Mihalescu Beatrice , Mihalescu Lucia ,   Technical University of Cluj-Napoca, North Universitary Center of Baia Mare, Faculty of Sciences, Department of Chemistry and Biology, 76 Victoriei Street, 430122 Baia Mare, Romania;, Voșgan Zorica ,   Technical University of Cluj-Napoca, North Universitary Center of Baia Mare, Faculty of Sciences, Department of Chemistry and Biology, 76 Victoriei Street, 430122 Baia Mare, Romania;, Maxim Aurel ,   University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Faculty of Agriculture, 3-5 Mănăștur St., 400372 Cluj-Napoca, Romania, Dumuța Anca ,   Technical University of Cluj-Napoca, North Universitary Center of Baia Mare, Faculty of Sciences, Department of Chemistry and Biology, 76 Victoriei Street, 430122 Baia Mare, Romania;, Pop Flavia ,   Technical University of Cluj-Napoca, North Universitary Center of Baia Mare, Faculty of Sciences, Department of Chemistry and Biology, 76 Victoriei Street, 430122 Baia Mare, Romania;
Published: February 2025

Cream cheese is one of the most commonly used dairy products. It has a soft, smooth texture with a slightly tangy flavor, and a pleasant taste, specific to the added seasoning. Horseradish is a food additive due to its sharp flavor and has antibacterial properties. The aim of this study was to perform a comparative analysis of three types of cow's milk cream cheese: two homemade varieties (simple cream cheese – SCC, cream cheese with horseradish – SCH, and commercial cream cheese with horseradish – CCC). For all three samples, organoleptic, physicochemical, and microbiological analyses were conducted. The results showed that the most appreciated sample from an organoleptic standpoint was CCC, due to its texture, flavor, and uniformity. In terms of physicochemical properties, CCC had the highest dry matter content, followed by SCH due to the addition of horseradish. The highest acidity was observed in the SCC sample, while a slight reduction in acidity was noted in the samples with horseradish. Microbial contamination was evident in SCC, followed by SCH, and absent in CCC. The CCC sample proved to be the most appreciated, thanks to the added ingredients that significantly balance the taste and texture, matching consumer preferences
Characterization of some jams obtained from exotic fruits
Authors:   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Uzun-Viruzab Mira , Voicilaș Daiana Rebeca ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Iacobescu Adela ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Rădulescu Laura ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Megyesi Corina I. ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania
Published: February 2025

With their rich nutrient content, fruits and vegetables are of a great importance. Fruits have a very varied chemical composition, generally having as basic element water (up to 90%) and also containing: sugars, proteins, fats, organic acids, various mineral salts, pectic substances and tannins, vitamins and enzymes, in varying amounts. Usually, in the production of jam, one fruit species is used as a raw material, but this study aimed to obtain a food product, rich in vitamins (D, E, K, B12, B6, B2, B1) and minerals, harmoniously blending some of the most beneficial fruits on body health: mango and pineapple. Three types of jam were obtained, namely: mango jam, pineapple jam and a combination between the first two, a mango and pineapple jam. From the analysis of these jams the following aspects can be highlighted: i) The sensory properties of the jams were evaluated and it was observed that the mango and pineapple jam was the most appreciated in terms of sensory characteristics: color, smell and taste; ii) the jams were analyzed from a physicochemical point of view, determining the acidity, the content of vitamin C and of sugar; iii) The highest value of acidity was determined for the mango and pineapple jam (0.48%), and the lowest value was recorded for mango jam (0.31%). As regards the vitamin C content, the highest value was found in the mango and pineapple jam assortment (1338,85 mg/L). More sugar content was found in the mango jam (74,6ºBrix), and the lowest sugar content was found in the mango and pineapple jam (71,5ºBrix)
Improving the antioxidant properties of sesame oil through the addition of natural bioactive compounds
Authors:   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Moigrădean Diana , Socaci Daniela-Florina ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Alda Liana-Maria ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Bordean Despina-Maria ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Stoin Daniela ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania, Poiana Mariana-Aten ,   University of Life Sciences "King Mihai I" from Timisoara, Faculty of Food Engineering, Aradului Street no. 119, 300645 Timisoara, Romania
Published: February 2025

Sesame (Sesamum indicum L.) is a valuable oilseed crop that contains several nutritious bioactive compounds. Sesame seeds have a high oil content (50-60%). They are rich in high quality unsaturated fatty acids. Sesame seeds contain phenolic compounds such as sesamin and sesamolin, which have been reported to be valuable compounds for human health. Sesame oil is obtained by cold pressing. Sesame oil has never been used as an edible oil; it has been and continues to be used as a condiment in traditional dishes in Asian countries. The purpose of this research was to determine the quality of the flavoured sesame oil obtained by the addition of vegetable spices to sesame oil (basil - Ocimum basilicum, garlic - Allium sativum, cumin - Cuminum cyminum and cinnamon - Cinnamomum zeylanicum). The addition of garlic, cumin, cinnamon or basil to sesame oil can provide additional benefits. Garlic is well known for its anti-microbial and antioxidant properties. Cumin can help with digestion and may also have anti-inflammatory properties. Cinnamon may have antimicrobial and antioxidant properties and may help control blood sugar levels. Basil is known to have anti-inflammatory, antioxidant and antimicrobial properties. The highest amount of total polyphenols was found in the oil samples flavoured with cinnamon. The highest antioxidant capacity was found in sesame oil samples flavoured with garlic. All these spices improve the quality of the oil through the addition of natural bioactive compounds.
Sensory and physical-chemical characterization of some range of beers from the Romanian market
Authors:   Department of Food Science, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania, Megyesi Corina I. , Hădărugă Nicoleta G. ,   Department of Food Science, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania, Velciov Ariana B. ,   Department of Food Science, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania, Rădulescu Laura ,   Department of Food Science, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania, Riviș Adrian ,   Department of Food Science, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania, Bujancă Gabriel ,   Department of Food control and expertise, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania, Rinovetz Alexandru ,   Department of Food Science, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania, Bordean Despina ,   Department of Food control and expertise, University of Life Sciences “King Mihai I” from Timișoara, Calea Aradului 119, 300645 – Timișoara, Romania
Published: February 2025

Beer is the first alcoholic drink consumed by humans, and the recipe for its manufacture is one of the oldest in human history. Beer is rich in nutrients such as calcium, phosphorus, potassium or zinc. This abundance is due to the fact that it is made of plants: barley, wheat and hops. It is a drink beneficial to the health of the human body (if it is consumed in adequate quantities), the soluble fibers in beer helping to prevent constipation and improve digestion. The aim of the study was to perform a sensory characterization of two types of light (pale) beer, purchased from the Romanian market. This involves a sensory evaluation, but also a centralization of the results from a group of tasters. Also, a physical-chemical characterization of the two types of beer was carried out, determining the alcohol concentration, total acidity and mass fraction of CO2
The Role of Symbolism in Liturgical Rites: A Theological and Anthropological Perspective
Authors: Amsikan Modesta
Published: February 2025

Symbolism plays a crucial role in liturgical rites, serving as a bridge between the sacred and the human experience. This study explores the theological and anthropological dimensions of symbolism in liturgical practices using a qualitative approach with literature review and library research methods. The study examines how symbols in liturgical rites convey theological truths and shape communal religious experiences. Theologically, liturgical symbols represent divine mysteries and serve as a medium for spiritual participation, reinforcing sacred doctrines and traditions. Anthropologically, these symbols function as cultural expressions, fostering a shared identity and deepening the sense of belonging within religious communities. This research highlights the interdisciplinary nature of liturgical symbolism by analyzing its historical evolution, cultural variations, and theological significance. Through an extensive review of scholarly sources, the study identifies key symbolic elements in various religious traditions, including gestures, sacred objects, and ritualistic language. The findings suggest that symbolism in liturgical rites not only preserves theological continuity but also adapts to socio-cultural changes, making religious worship both timeless and contextually relevant. However, challenges such as secular influences and modernization pose a risk to the depth of symbolic meanings in contemporary worship. The study concludes that understanding the dual theological and anthropological function of liturgical symbols is essential for preserving their significance in worship. Future research should explore how evolving cultural contexts shape the interpretation of symbols in liturgical rites, ensuring their continued relevance in modern religious practice.
Student Organizational Commitment: effect of Psychological Capital and Support Social
Authors: Ilis N. , Lutfi Ikhwan , Baidun Ahmad
Published: February 2025

This study aims to examine the effect of social capital and social support on organizational commitment. This study involved 233 students studying in Jakarta, who were taken by non- random sampling with convenience techniques. The research instruments consisted of the Organizational Commitment Questionnaire (OCQ) scale, the Psychology Capital Questionnaire (PCQ) scale developed by Luthans et al., and the social support scale based on Sarafino's theory. The results showed that psychological capital and social support contributed significantly in a positive direction and the proportion of variance was 36.2%.
Pendidikan Bahasa Arab bagi Siswa Berkebutuhan Khusus Tuna Grahita di Madrasah Inklusi
Authors: Astuti Erma Hari Tri , Khilmah Khilmah , Marlika Titim , Sa'adah Nila
Published: February 2025

Arabic language education for students with intellectual disabilities (ABK tunagrahita) in inclusive madrassas requires adaptive methods, effective media, and cross-stakeholder collaboration to achieve optimal outcomes. This study aims to analyze effective teaching methods, challenges faced by teachers, and the collaboration between teachers, parents, and therapists in teaching Arabic to ABK. Using a qualitative approach through literature reviews, the study found that individualization, multisensory, and demonstration methods are key to successful learning. Media such as flashcards, digital applications, and concrete objects help students grasp abstract concepts like Arabic letters. Major challenges faced by teachers include limited resources, insufficient specialized training, and communication barriers with students. However, effective collaboration among teachers, parents, and therapists enhances learning consistency and creates a supportive environment tailored to the individual needs of students. This study contributes to the development of inclusive Islamic education, particularly for students with intellectual disabilities.
Capítulo 16: Propuesta conceptual desde un enfoque multidimensional del término “Competencias”
Authors:   Universidad de Guayaquil, Narváez Vásquez Germán Aníbal
Published: February 2025

El término competencia ha suscitado una variedad de interpretaciones, lo que ha generado diferentes enfoques y en algunos casos, confusión, debido a su naturaleza polisémica. Esto implica que su significado se adapta a las particularidades del contexto y al discernimiento de quienes lo aplican en un momento determinado. De manera general, se concibe como un conjunto articulado de actitudes, conocimientos y destrezas que posibilitan la ejecución eficiente de funciones y tareas, bajo parámetros de desempeño establecidos, principalmente en el ámbito profesional. El presente estudio tiene como propósito analizar las múltiples interpretaciones del concepto de competencia, proponiendo una definición global que integre sus componentes esenciales, a fin de lograr una comprensión más precisa del término. Sin embargo, se reconoce que su aplicación en diversos contextos le confiere un carácter multiconceptual, lo que dificulta su delimitación en un marco conceptual único. Para la investigación, se empleó la metodología de análisis de contenido, con la que se procedió a codificar las características fundamentales del concepto, transformándolas en unidades que permitieron su descripción y análisis riguroso. La muestra estuvo conformada por las definiciones de 38 autores, organizadas en quince categorías correspondientes a tres enfoques teóricos predominantes en el contexto organizacional actual.
Capítulo 17: Orientación de la Investigación en la Salud Pública Veterinaria
Authors:   Universidad Técnica de Babahoyo, Gómez Villalva Juan Carlos
Published: February 2025

Este capítulo aborda la importancia de la investigación en la salud pública veterinaria, resaltando su papel en la prevención de enfermedades zoonóticas y la protección de la salud humana, animal y ambiental. El objetivo es proporcionar un enfoque integral para el desarrollo de la investigación en este campo, considerando metodologías adecuadas y el impacto del discurso académico en la formación de futuros investigadores. La metodología se centra en enfoques epidemiológicos y técnicas avanzadas, como el uso de la tecnología en la investigación interdisciplinaria. A través de estudios de casos, revisiones bibliográficas y análisis de datos, se exploran diversas estrategias para la gestión de enfermedades. Los resultados muestran que el enfoque "Una Sola Salud" y el uso de tecnologías avanzadas, como la radiación gamma en la seguridad alimentaria y el control de vectores, son fundamentales para mejorar la respuesta ante enfermedades zoonóticas. En conclusión, la aplicación efectiva de la investigación en salud pública veterinaria es clave para abordar los desafíos sanitarios actuales. Es necesario seguir impulsando la formación de investigadores capaces de integrar múltiples disciplinas y aplicar sus conocimientos a nivel global.
Capítulo 18: La política nacional de emprendimiento y el ecosistema emprendedor en el sector rural en Colombia
Authors:   Universidad del Sinú, Pérez Vázquez Manuel Antonio
Published: February 2025

El presente artículo, pretende examinar, si la Política Nacional de Emprendimiento en Colombia, posibilita las condiciones del ecosistema emprendedor en el sector rural. La investigación se caracteriza por ser de tipo descriptivo –cualitativo, apoyada en el acopio de información de fuente secundaria con base en normas, documentos y bibliografía relevante, sobre el sector agrícola, los lineamientos nacionales de emprendimiento y su conectividad con el ecosistema emprendedor rural. Los hallazgos sugieren, que el desarrollo de programas de capacitación, la promoción de la colaboración y la creación de redes, la inversión en infraestructura tecnológica, el apoyo financiero y la adopción de un enfoque integral para el desarrollo rural son elementos clave para impulsar el emprendimiento en las zonas rurales del país. En la discusión, se plantea, que la política nacional de emprendimiento rural, este en función de consolidar un macroproyecto institucional, que permita atender las falencias particulares del sector rural. En la conclusión, la Política Nacional de Emprendimiento se ha centrado en desarrollar la cultura emprendedora, sofisticar los mecanismos de financiamiento, fortalecer las redes y estrategias de comercialización, impulsar el desarrollo tecnológico y la innovación, y consolidar la arquitectura institucional para el emprendimiento, en su ruta estratégica hacia el desarrollo rural.
Humming While We Work: Reflections on Music in the Operating Room
Authors: Tribble Curt
Published: February 2025

No abstract present.
Technological revolution in mental health- A vision from a historical perspective
Authors: Fahmawi Shaza , Abudalu Abedelrahman
Published: February 2025

The digital revolution is evolving at an unstoppable pace. Alongside the unprecedented explosion of digital technology facilities and systems, mental health care is under greater pressure than ever before. With its emphasis on big data, computing power, mobile technology, and network information, digital technology is set to transform health care delivery. This article reviews the field of digital health technology assessment and intervention primarily in secondary service mental health care, including the barriers and facilitators to adopting and implementing digitally mediated interventions in service delivery. We consider the impact of digitally mediated communication on human interaction and its potential impact on various mental states such as those linked to mood, anxiety but also well-being. These developments point to a need for both theory- and data-driven approaches to digital health care. We argue that, as developments in digital technology are outpacing the evaluation of rigorous digital health interventions, more advanced methodologies are needed to keep up with the pace of digital technology development. The need for co-production of digital tools with and for people with chronic and mental health difficulties, and implications of digital technology for psychotherapy practice, will be central to this development.
Analisis Potensi Bahaya dan Upaya Pengurangan Tingkat Risiko Kecelakaan Kerja Menggunakan Metode HIRADC Pada Poli KIA UPTD Puskesmas Candilama Kota Semarang
Authors: Diona Diona , Sifai Izzatul Alifah , Anto Arif Mahatma
Published: February 2025

Puskesmas merupakan tempat kerja yang memiliki potensi terjadinya kecelakaan kerja seperti tertusuk jarum hingga korsleting aliran listrik penyebab kebakaran. Penelitian ini bertujuan mengidentifikasi potensi bahaya yang terdapat di poli KIA UPTD Puskesmas Candilama Kota Semarang serta memberikan usulan rekomendasi upaya pengendalian untuk menurunkan tingkat risiko. Metode penelitian yang digunakan yaitu kualitatif dan kuantitatif dengan pendekatan cross sectional. Data primer didapat melalui observasi dan wawancara. Teknik pengolahan data dengan menggunakan metode HIRADC. Hasil observasi ditemukan 15 potensi bahaya pada 5 ruangan yang terdapat di poli KIA. Potensi bahaya terdiri dari 9 bahaya fisik, 1 bahaya ergonomi, 2 bahaya kimia, 2 bahaya biologi serta 1 bahaya psikososial. Penilaian risiko pada kondisi awal bahaya dengan kategori low risk sebesar 20%, kategori medium risk dan high risk masing- masing sebesar 33,3% dan extreme risk sebesar 6,66%. Setelah dilakukan usulan rekomendasi pengendalian risiko kemudian terjadi perubahan yang signifikan yaitu potensi bahaya dengan kategori low risk sebesar 93,3% dan medium risk  sebesar 6,7%. Rekomendasi upaya pengendalian risiko diberikan dengan menyesuaikan kondisi di lapangan dan hierarki pengendalian antara lain memberikan pelatihan kepada petugas dalam menggunakan jarum suntik dan alat medis lainnya, mengedukasi penerapan budaya 5R, menjadwalkan safety patrol serta mengatur ulang pemasangan stop kontak dan kabel sesuai standar
Automating FDA Compliance: The Role of AI in Computer System Validation (CSV)
Authors: Amarapalli Lalitha , Muthirevula Gnanendra Reddy
Published: February 2025

The increasing adoption of artificial intelligence (AI) in the pharmaceutical and healthcare industries has transformed regulatory compliance processes, particularly in Computer System Validation (CSV). The U.S. Food and Drug Administration (FDA) mandates strict compliance with CSV to ensure the reliability, accuracy, and integrity of computer systems used in drug development, manufacturing, and clinical trials. Traditional CSV methods are often time-consuming, labor-intensive, and prone to human error. AI-driven automation offers a solution by streamlining validation processes, reducing costs, and enhancing regulatory adherence. This paper explores the role of AI in automating CSV, highlighting its potential to improve efficiency, ensure data integrity, and minimize compliance risks. Additionally, it discusses the challenges and regulatory considerations associated with AI-driven CSV, providing insights into how organizations can leverage AI to meet FDA requirements effectively.
Research on the Social Attributes and Influences of Film and Television Works
Authors: Fung Winglam
Published: February 2025

The social characteristics and wide-ranging impacts of films and television shows are thoroughly examined in this essay, which maintains that these media serve important social purposes including social reflection, cultural communication, and value formation. It is discovered that films and television shows have a big influence on how social issues are expressed and reflected, in addition to being crucial for cultural innovation and inheritance and the formation of social values. Young people’s development, the social climate, and the creation and execution of public policies are all significantly impacted by films and television shows. These impacts are not favorable, either, since poor television shows and movies can harm the social climate and the development of young people. Based on this, this paper makes recommendations for improving the supervision and guidance of films and television shows, raising awareness of their social responsibility, bolstering their social function, and encouraging teens’ healthy development. By putting these recommendations into practice, the goal is to raise the social worth of movies and television shows, lessen any possible harm they may do, and encourage the peaceful advancement of society.
Liability Allocation in Autonomous Vehicles: From Ethics to Law
Authors: Huang Haoyu
Published: February 2025

This paper addresses the complex issue of liability allocation in autonomous vehicle accidents, considering both legal and ethical perspectives. With the rapid development of autonomous driving technology, traditional legal frameworks struggle to cope with the new challenges posed by driverless vehicles. The ambiguity in liability arises from the involvement of multiple parties, including vehicle manufacturers, software developers, and car owners. Ethically, decisions made by autonomous vehicles in unavoidable accident scenarios raise difficult questions about moral responsibility, such as whether to prioritize passengers or pedestrians in emergency situations. The paper explores these ethical dilemmas, using the “Trolley Problem” as a reference, and argues for the development of an ethical framework for algorithmic decision-making. Additionally, the paper critiques the lag in legal adaptation and proposes reforms to establish clear liability frameworks. In conclusion, it emphasizes the need for a legal system that integrates technological progress with ethical considerations to ensure fairness and accountability in the era of autonomous vehicles.
Comparative Analysis of Icarrin and Curcumol as a Therapy for Pancreatic Cancer and Breast Cancer
Authors: Wang Yuning
Published: February 2025

Breast cancer is the second most common type of cancer in American women. The incidence of pancreatic cancer has significantly risen over the past few decades. This study investigates whether icariin (ICA) and curcumin can show a more pronounced ability to inhibit tumor cell proliferation, induce apoptosis, and suppress cell migration and invasion in pancreatic and breast cancers. However, the specific impacts on different cancer types may vary. The objective of this research is to assess and compare the influence of ICA and curcumol on SNU-2466 pancreatic cancer cells and MCF7 breast cancer cells. The findings demonstrate that ICA and curcumol demonstrate a better effect on pancreatic cancer cells than in MCF7 breast cancer cells. Additionally, these compounds exhibit a stronger inhibitory effect on the PI3K/Akt/mTOR signaling pathway in pancreatic cancer cells compared to breast cancer cells. These results suggest that ICA and curcumol have more significant therapeutic potential in treating pancreatic cancer.
Research on the Limitations and Paths of Innovative Development of Biographical Films
Authors: Zhong Yi
Published: February 2025

For a long time, the film art form of biographical films has been relatively fixed and has not undergone revolutionary development for a long time. However, Christopher Nolan’s Oppenheimer the latest typical film of this type has broken the long-standing rules and regulations of biographical films, expanded the margins of biographical films, and provided a reference for the subsequent creation of related types of films. This article analyzes the limitations and innovations of biographical films represented by Oppenheimer. This paper argues that biographical films are limited by definition and connotation, and their form and gender perspective have certain limitations. Therefore, there are certain difficulties in the innovation of this type of film. This paper argues that Oppenheimer breaks the linear constraints of biographical film time narratives, and at the same time uses more original soundtracks and sound effects that conform to the narrative connotation of the film. All of this gave Oppenheimer a new perspective. This article concludes that biographical films need to show more of the spiritual core of biographical characters while moving closer to commercialization to trigger audience thinking.
Unveiling the Potential Risks: Long-Term Health Effects of Chronic Exposure to Bisphenol A
Authors: Liu Yingtong
Published: February 2025

The effects of bisphenol A (BPA) on estrogen levels, fertility, obesity, and liver injury were investigated. Through a series of control results (CR1 to CR16), this study examined the multiple effects of BPA on biological processes. The findings show that when exposed to BPA, estrogen levels rise, fertility decreases, obesity increases through changes in liver weight, and damage can be observed through confocal imaging. These results varied in different settings, suggesting partial or full support for the original hypothesis that BPA has various effects on estrogen, fertility, obesity, and liver damage. It is worth noting that in some cases, such as CR5, estrogen levels are not affected by BPA, but fertility, obesity, and injury are. In contrast, CR16 significantly refuted this hypothesis, suggesting that BPA may not have a substantial effect on estrogen, fertility, obesity, or impairment in specific situations. Overall, the study highlights the complex relationship between BPA exposure and biological systems, underscoring the need for further research to fully understand the effects of this compound on estrogen regulation, fertility, obesity development, and liver health. These findings provide valuable insights into the complex interactions between BPA and human physiology.
Impacts of Information Cocoon and Potential Solutions
Authors: He Binghua
Published: February 2025

The information cocoon refers to the closed information environment that an individual forms under the influence of subjective preferences and algorithmic recommendations. This phenomenon has become more prominent with the rapid development of the internet and big data technology, having a profound impact on personal cognition, social interaction, and social governance. The information cocoon not only leads to the one-sidedness of individual cognition and the weakening of critical thinking but also intensifies social division and group polarization. At the same time, it challenges social governance, causing issues such as opinion fragmentation, the spread of false information, and increasing governance costs. This paper analyzes the formation mechanism of the information cocoon and its multi-dimensional impacts on cognition, society, and governance, and proposes countermeasures based on existing research, including optimizing algorithm design, improving public information literacy, and strengthening policy regulation, aiming to provide theoretical support and practical guidance for solving the information cocoon problem.
Explore the Mechanism of Taiji(Tai Chi) Promoting Physical and Mental health
Authors: Xiong Jingyi
Published: February 2025

This paper aims to explore the mechanisms by which Tai Chi affects physical and mental health, by reviewing relevant research and analyzing the role of Tai Chi in the musculoskeletal system, nervous system, endocrine system, and immune system. Tai Chi can relax the body’s muscles, promote blood circulation, alleviate pain and stress, improve the pattern of force generation and balance ability, and has a certain effect on relieving lumbar disc herniation. It can also regulate the release of neurotransmitters such as serotonin and dopamine, activate the parasympathetic nervous system, achieve deep relaxation, and reduce stress levels. Not to mention Tai Chi can mobilize the regulatory functions of the neuro-endocrine-immune system, affect the activity of immune cells and the levels of immunoglobulins, and have a positive impact on the immune system. In clinical applications, Tai Chi is suitable for the rehabilitation of various diseases and is particularly beneficial for the elderly and patients with chronic diseases. Future research should further explore its specific mechanisms, conduct large-scale clinical trials, and develop personalized training programs. In summary, Tai Chi has comprehensive benefits for physical and mental health and is recommended for long-term practice under proper guidance.
The oncolytic virus of p53-armed NDV, in combination with GM-CSF and iPD-L1, induces the Immunogenic cell death of melanoma
Authors: Chen Ziyu , Xie Shuning , Tan Xiaoxuan , Yu Xiaoran , Qi Lexi
Published: February 2025

Melanoma is a malignant tumor that mutates from melanocytes on the skin and mucous membranes. (Long et al., 2023) Cutaneous melanoma is the most dangerous skin cancer, which causes 80% of causalities (Saeed et al., 2024). The treatment of melanoma includes wide excision and radiotherapy, which makes it hard to perform a systematic impact and could produce side effects (Sakunchotpanit et al.,2024). As immunotherapy, oncolytic virus therapy provides a pathway to combine a direct attack of this cancer, leading to a favorable prognosis. However, oncolytic virus therapy is fraught with challenges as the generally immunosuppressive tumor microenvironment interferes with inducing an effective systemic immune response. To overcome the immunosuppression, activate the innate immune response, and cause an abscopal effect in tumor treatment, we propose building on a previously described recombinant Newcastle disease virus (NDV) encoding GM-CSF, MEDI5395. Oncolytic virotherapy induces immunogenic cell death (ICD) and antitumor immune responses, which can cause the abscopal effect simultaneously. It has previously been shown that p53 expression in OVs can induce more severe ICD and enhance T-cell infiltration, leading to reduced tumor growth and long-lasting systemic anti-tumor immune response in preclinical models by secreting adenosine triphosphate (ATP) and high-mobility group box protein B1(HMGB1). In this way, untreated tumor cells are also suppressed. iPD-L1 combined with GM-CSF effectively reduces tumor viability, enhances immune cell infiltration, and upregulates immune-related genes, promoting systemic anti-tumor immunity and improved survival in mouse melanoma models. We hypothesize that NDV encoding p53 and iPD-L1/GM-CSF effectively induce immunogenic cell death, enhance immune cell infiltration, and reduce tumor growth, demonstrating significant therapeutic potential in preclinical models. In conclusion, editing such genes in NDV can potentially enhance melanoma’s treatment efficacy, resulting in systemic anti-tumor responses.
An In-depth Exploration of Psychology: Definitions, Research Methodologies, and Applications
Authors: Zhang Siyi
Published: February 2025

This paper comprehensively examines the field of psychology, elucidating its definition, research techniques, and practical applications. It delves into the understanding of psychological disorders, theoretical models, and treatment modalities, emphasizing the significance of scientific inquiry and a holistic approach to grasping human behavior and mental processes.
Totipotency Studies in Hemicordates: Exploring Non-Mammalian Stem Cell Regulation
Authors: Zhang Wenjing
Published: February 2025

In this paper, the totipotency of non-mammalian stem cell regulation is discussed, especially the totipotency of hemicordate. Hemicornities play an important role in ecosystems, and studying their totality will help to better understand the adaptation mechanisms, niches, and biodiversity of these organisms. This paper introduces a method to observe cell development in different parts of hemicordate by fluorescent labeling to evaluate its totipotency.
Liver Damage Induced by Cadmium via mTOR-Mediated Autophagy in Hepatocytes
Authors: Wang Yingjia
Published: February 2025

Cadmium (Cd) is one of the environmental pollutants that induces hepatotoxicity, but the mechanism remains unknown. In this study, we aimed to probe whether mTOR-dependent autophagy was involved in Cd-induced liver damage in vivo and in vitro. AML12 cells were exposed to various concentrations of CdCl2 for 6, 12, 24hr, or C57BL/6 mice were given CdCl2 solution for 3 days via oral administration. Cell viability was measured by CCK-8 assay. The expression of p-mTOR or LC3 protein was measured with western blotting or immunofluorescence, as well as liver damage via H&E staining. This study focused on the effect of Cd on liver injury, including the mTOR pathway and autophagy, which provides new ideas for further study on the damage mechanism of environmental pollutants.
The Impact of Misinformation on Public Health Initiatives and Perceptions
Authors: Cao Huiyang
Published: February 2025

The COVID-19 pandemic represents both a major global health crisis and an infodemic. The pandemic was characterized by large amounts of misinformation, mostly propagated through social media. This study aimed at investigating the impact of misinformation on public health initiatives and perceptions during the pandemic. The study showed that vaccination was a major public health initiative to manage the pandemic, and the spread of misinformation was associated with increased vaccine hesitancy and lower vaccine uptake. The study also found evidence of socioeconomic and racial differences in the impact of misinformation on vaccine hesitancy. Misinformation was also associated with reduced public trust in either government or public health experts, and this relationship was mediated by political polarization and the politicization of the pandemic. Misinformation about the COVID-19 pandemic also had negative implications on the economy, which could potentially reduce the availability of public health funding. Lastly, misinformation had a significant negative impact on the public perception of public health guidelines, which resulted in reduced compliance with them.