bluuebunny/crossref_metadata_2025 huggingface dataset:
Aesthetic Rehabilitation of the Severe Bone Loss on Anterior Region Using Andrew’s Bridge: A Case Report
Authors: Daniati Reni Puspa , Rostiny  , Hendrijantini Nike
Published: December 2020

A patient with several missing teeth in the anterior region usually experiences severe hard and soft tissue loss, posing a greater challenge for the prosthodontist to treat. This is a case of a 50-year-old female patient who came to the RSGMP UNAIR department of prosthodontics needing to replace the old denture that felt loose and had a change of color to rehabilitate the loss of large residual ridges involving hard and soft tissue. The patient has lost the central and lateral right maxillary incisors with severe hard and soft tissue defect after cyst removal in the region. The patient considered to restore an anterior region with severe hard and tissue loss. Andrew’s Bridge successfully restores an anterior region with severe hard and soft tissue loss.
Comparison of the most popular methods for predicting stonefree rate after percutaneous nephrolithotomy
Authors: Ugalde-Resano Rodrigo , Villeda-Sandoval Christian Isaac , Kobashi-Sandoval Elisa , Rivera-Ramírez José Alejandro , Vargas-Robles Manuel Alexis , Méndez-Probst Carlos Enrique
Published: December 2020

BACKGROUND: The Guy’s stone score, S.T.O.N.E. nephrolithometry, CROES nomogram, and S-ReSC scoring system have recently been externally validated as effective predictors of stone-free rate after percutaneous nephrolithotomy.OBJECTIVE: We describe herein the advantages of identifying the most accurate scale and propose its standardized use.MATERIALS AND METHODS: We analyzed 188 patients that underwent percutaneous nephrolithotomy for kidney stones within the time frame of October 2010 and July 2015 at a tertiary care referral center. Preoperative and postoperative non-contrast computed tomography scans were used in all patients to compare the four scoring systems, using the strict criterion of absolute absence of residual stone as the stone-free rate.RESULTS: The overall stone-free rate was 57.9%. All scoring systems presented a statistically significant stone-free rate (p<0.001). Only the Guy’s stone score had no correlation with postoperative complications. The four scoring systems had similar accuracy, none of them were more predictive for stone-free rate than the other, and there was no significant difference in the areas under the curve between them (p=0.2). In addition, each scale had a correlation with operative time and length of hospital stay.CONCLUSIONS: The four scales analyzed were excellent predictors for stone-free rate. They had similar receiver operating characteristic curves and areas under the curve, with no significant differences between them. However, the Guy’s stone score presented the best predictive capacity and the S-ReSC scoring system was the best method for predicting complications. It is up to the urologic community to decide which evidence-based scale is the most suitable. Meanwhile, the need for a standardized method continues to grow. KEYWORDS: Stone-free rate; Percutaneous nephrolithotomy; CROES; S-ReSC, S.T.O.N.E.; Guy’s stone score
Comparación del Índice Internacional de Síntomas Prostáticos versus Escala Visual Análoga Gea® para la evaluación de los síntomas de la vía urinaria inferior
Authors: Preciado Estrella Diego
Published: December 2020

ANTECEDENTES: en 1992 la OMS aprobó el IPSS para evaluar los síntomas del tracto urinario inferior en pacientes de países industrializados; sin embargo, existen poblaciones donde el cuestionario resulta complicado y se obtienen resultados erróneos o falsos.OBJETIVO: comparar el Índice Internacional de Síntomas Prostáticos (IPSS) versus Escala Visual Análoga Gea (EVA-GEA®) en pacientes con síntomas del tracto urinario inferior.MATERIALES Y MÉTODOS: estudio transversal, comparativo y analítico, efectuado en el Hospital Dr. Manuel Gea González, entre marzo y julio de 2016. Se evaluaron hombres mayores de 45 años de edad, con síntomas del tracto urinario inferior, mediante la aplicación del IPSS y la Escala Visual Análoga Gea (EVA-GEA), desarrollada con especialistas en Foniatría y Diseño Gráfico. Se registraron las variables sociodemográficas, precisión y tiempo de respuesta. Para el análisis estadístico se utilizó la χÇ para variables continuas, t de Student para distribución de medias y prueba de Wilcoxon para comparar la mediana de ambas muestras y determinar sus diferencias. Los resultados se analizaron con el programa SPSS (versión 22.0, IBM).RESULTADOS: se registraron 121 pacientes, con promedio de edad de 67 años; escolaridad de 7 años, 35% desempleados, 8% con lengua indígena. Cincuenta y cuatro (40%) pacientes solicitaron ayuda para responder el IPSS por limitaciones visuales y socio-intelectuales versus 14 (11%) casos que respondieron la EVA-GEA; así, 87% pudo completarla (χ² = 11.68, p < 0.05). El tiempo promedio para completar el IPSS fue de 280 versus EVA-GEA de 170 segundos (t Student 19.64, p < 0.05).CONCLUSIONES: La Escala Visual Análoga Gea se propone como alternativa al IPSS para evaluar los síntomas de tracto urinario de pacientes con limitaciones intelectuales, lingü.sticas, académicas o sensoriales.PALABRAS CLAVE: escala visual análoga, síntomas del tracto urinario inferior, IPSS.
Quemadura eléctrica en el pene tratada con penectomía parcial. Reporte de un caso
Authors: Piñon Enrique Omar
Published: December 2020

ANTECEDENTES: las quemaduras eléctricas de alto voltaje en el pene son sucesos poco frecuentes, asociados con alta morbilidad y mortalidad, que pueden causar lesiones devastadoras y afectar la función eréctil, calidad de vida y aspecto psicológico del paciente.CASO CLÍNICO: paciente de 28 años de edad, atendido en el área de choque del Centro Médico Adolfo López Mateos (ISEM) por quemadura eléctrica con expansión hacia los genitales. A la exploración física se observaron lesiones en el antebrazo derecho y el pene, con necrosis y pérdida de la función de la uretra, cuerpos cavernosos y esponjosos en 2 tercios distales y la formación de un “globo” vesical con retención aguda de orina. Se decidió la cistostomía suprapúbica, debridación extensa del tejido necrótico y penectomía parcial, sin incidencias posoperatorias. El paciente se encuentra en protocolo de reconstrucción peneana anatómica y preservación de la función miccional.CONCLUSIONES: las quemaduras eléctricas en los genitales son sucesos excepcionales. Entre las opciones de tratamiento quirúrgicourológico más importantes se encuentran la preservación y recuperación de funcionalidad del pene en los pacientes jóvenes.PALABRAS CLAVE: quemadura eléctrica, penectomía parcial, tratamientopor quemadura eléctrica.
Reflujo vesicoureteral sintomático posterior al injerto renal en adultos: tratamiento endourológico y reacción con agentes bloqueantes
Authors: Gutiérrez-Jimenez Angel Armando
Published: December 2020

El reflujo vesicoureteral después del trasplante renal es una complicación común, que puede favorecer la aparición de infección de vías urinarias recurrente y cuadros de pielonefritis aguda en el injerto, lo que incrementa el riesgo de su pérdida. Por consenso general, los pacientes con reflujo vesicoureteral sintomático deben recibir tratamiento. El tratamiento endourológico ha demostrado curar el reflujo y disminuir el índice de infección de vías urinarias y pielonefritis con pocas complicaciones. En las últimas décadas se han prescrito diferentes fármacos e implementado diversas técnicas para el tratamiento del reflujo vesicoureteral sintomático posterior al trasplante renal. Este artículo revisa las diferentes técnicas utilizadas y analiza la eficacia de los distintos fármacos prescritos para el reflujo vesicoureteral sintomático posterior al trasplante renal en adultos.
Extrusión del esfínter artificial uretral externo. Caso clínico y revisión de la bibliografía
Authors: Arias Zapien Alejandro Severo , Torres Ochoa Dora Elizabeth
Published: December 2020

ANTECEDENTES: la prevalencia de incontinencia urinaria posterior a la prostatectomía radical se ha incrementado en los últimos años, debido al aumento de cirugías realizadas anualmente. La colocación del esfínter artificial uretral externo representa un método efectivo para el control de la incontinencia urinaria masculina, principalmente provocada por prostatectomía radical.CASO CLÍNICO: paciente masculino de 70 años de edad, intervenido para prostatectomía radical, con incontinencia urinaria total. Después de la colocación del esfínter artificial uretral externo, acudió a consulta por dolor intenso en el escroto e inactivación del esfínter artificial; al cuarto mes posquirúrgico tuvo extrusión del dispositivo de la válvula por la bolsa escrotal. Se realizaron dos incisiones: una en la línea media suprapúbica para retirar el reservorio del esfínter artificial uretral externo y la otra en la línea media del rafe escrotal para retirar el dispositivo valvular extruido y el manguito localizado en la uretra bulbar. El paciente evolucionó sin complicaciones, se retiró el drenaje a las 72 h y la sonda de cistostomía al mes posquirúrgico. Hasta la fecha permanece sin complicaciones. El último estudio de control de antígeno prostático específico se efectuó en octubre de 2016, con concentración de 0.03 ng/mL.CONCLUSIONES: la válvula del esfínter artificial uretral externo debe colocarse en la bolsa escrotal, del lado dominante del paciente, lateral al cordón espermático y al testículo. El dominio de la técnica quirúrgica y la selección adecuada del paciente representan el factor determinante para el éxito de la cirugía.PALABRAS CLAVE: esfínter, extruido, artificial, incontinencia, prostatectomía.
Complicaciones por el uso de bolsas recolectoras de orina con válvula antirreflujo versus modificada de Chavolla en pacientes con hematuria
Authors: Chavolla-Canal Alan Johan , Dubey-Malagon Luis Antonio , Mendoza-Sandoval Alejandra Ahtziri , Vazquez-Perez Daniel
Published: December 2020

ANTECEDENTES: La disfunción de la bolsa recolectora de orina afecta todo el sistema de drenaje urinario y provoca consecuencias importantes para los pacientes.

OBJETIVO: Analizar las complicaciones originadas por el uso de la bolsa recolectora de orina tradicional disponible y compararlas con las de la bolsa modificada de Chavolla.

MATERIALES Y MÉTODOS: Estudio prospectivo, transversal, no aleatorizado, efectuado en pacientes con diagnóstico de hematuria persistente que requirieron sonda transuretral con cistoclisis y bolsas recolectoras de orina. Los pacientes se dividieron en grupo 1: bolsa tradicional y grupo 2: bolsa modificada de Chavolla. Para el análisis estadístico se utilizaron medias y desviación estándar de las variables cuantitativas y proporciones (frecuencias) de las variables cualitativas. Los resultados de las medias y desviación estándar se compararon con t de Student y las frecuencias con c2. 

RESULTADOS: Se registraron 35 pacientes: 10 en el grupo 1 y 25 en el grupo 2. Ambos tuvieron edad y comorbilidades similares. En todos los pacientes del grupo 1 falló el sistema de drenaje y requirieron el cambio por la bolsa modificada de Chavolla (tiempo promedio de 3 horas). En el grupo 2 no se registraron fallas de la bolsa colectora de orina. La principal complicación en todos los casos fue la obstrucción de la bolsa por un coágulo, sin atribuirse per se a la intensidad del sangrado.

CONCLUSIÓN: La bolsa recolectora de orina modificada de Chavolla es efectiva en pacientes con cistoclisis por hematuria.
Determinación de parámetros uroflujométricos y su relación con parámetros antropométricos en hombres mexicanos sin síntomas urinarios
Authors: Preciado Estrella Diego Antonio
Published: December 2020

OBJETIVO: Determinar los parámetros uroflujométricos en hombres sanos sin síntomas urinarios y asociarlos con medidas antropométricas para establecer los límites de normalidad en México.MATERIALES Y MÉTODOS: Estudio prospectivo, descriptivo y analítico, efectuado en hombres menores de 40 años, sanos, sin síntomas o instrumentación urinaria. Se midieron los parámetros antropométricos y se realizaron tres uroflujometrías a cada individuo. Se efectuó la calibración periódica del uroflujómetro (disco Mediwatch©) y otras buenas prácticas urodinámicas para obtener resultados más certeros. El análisis de los resultados se llevó a cabo mediante estadística descriptiva (medidas de tendencia central, desviación estándar) e inferencial (tablas de contingencia, c2), para establecer asociaciones con significación estadística.RESULTADOS: Se incluyeron 77 hombres, con edad promedio de 25.9 años (DE ± 6.18), peso 78.9 kg (DE ± 14.4), estatura 172 cm (DE ± 6.3), IMC 26.8 kg/m2 (DE ± 4.64), perímetro abdominal 93 cm (DE ± 11.8), Qmax 28.01 mL/seg (DE ± 8.12), volumen-vaciado 313 mL (DE ± 94.98), tiempo 27.19 segundos (DE ± 7.6). El análisis por subgrupos, eliminando el rango intercuartilar y comparando el grupo de pacientes obesos versus delgados (IMC), encontró un Qmax de 27.9 vs 31.03 (c2 = -0.434, p>0.05); al comparar el perímetro abdominal se obtuvo 28.8 vs 25.31 mL/seg para los delgados y obesos, respectivamente (c2 = 2.901, p>0.05). Se observó un descenso de 1.68 mL/seg en el Qmax después de una década.CONCLUSIONES: Los varones mexicanos tienen una velocidad de flujo de 28 mL/seg, con descenso de 1.68 mL/seg por cada década de vida. Si bien el sobrepeso no afecta la potencia del chorro miccional, existe tendencia a ser mayor en la población obesa.PALABRAS CLAVE: Uroflujometría; síntomas urinarios; sobrepeso.
Adenocarcinoma of the rete testis associated with castration-resistant prostate cancer
Authors: Cortez-Betancourt Roberto , Ramirez-Garduño Emilio , Alías-Melgar Alejandro , Carreño-De La Rosa Fernando , Botello-Gómez Pedro Jair , Trujillo-Vázquez Eric Iván , González-Serrano Adolfo
Published: December 2020

BACKGROUND: Adenocarcinoma of the rete testis is a very rare diagnosis with only about 60 reported cases. To the best of our knowledge, the present report is the first on that tumor associated with prostate cancer. CLINICAL CASE: An 84-year-old man with a history of castration-resistant prostate cancer presented with a non-tender, solid, right testicular mass. Tumor markers were within normal limits. The patient underwent radical inguinal orchiectomy and the pathology study reported adenocarcinoma of the rete testis. Diagnosis was confirmed through immunohistochemistry and staining was positive for high molecular weight cytokeratin (CK HMW) and cytokeratin 5/6, and negative for PSA. CONCLUSION: Adenocarcinoma of the rete testis is a very rare condition. Clinical presentation of those tumors is nonspecific, and the diagnostic immunohistochemistry profile has not been well defined. Prognosis is poor, with a short overall survival rate. KEYWORDS: Adenocarcinoma; Immunohistochemistry; Orchiectomy; Rete testis; Testicular neoplasms
Colocación de un balón de oclusión ureteral para el tratamiento de la fístula urinaria posterior a trasplante renal. Reporte de un caso
Authors: Ramirez Martinez Isaac Alejandro , Garcia Vasquez Roberto Antonio , LopezChente Casado Justino , Vega Castro Ramiro , Vazquez Galvez Ariel , Garcia Martinez Francisco Enrique , Lopez Garcia Ana Laura , Razo Garcia Jorge Arturo , Galeana Maya Octavio
Published: December 2020

ANTECEDENTES: La incidencia de fístula urinaria posterior a un trasplante renal varía de 1.2-8.9%; esta complicación se ha relacionado con necrosis isquémica del uréter. Se recomienda la aplicación de un catéter doble J para disminuir su incidencia. CASO CLÍNICO: Paciente femenina de 42 años que recibió trasplante renal de donador cadavérico, con reimplante ureterovesical mediante la técnica Lich-Gregoir para anastomosis. Catorce días después del procedimiento inició con salida espontánea de orina por el sitio donde se localizaba el drenaje quirúrgico. El tratamiento inicial consistió en derivación vesical durante cuatro semanas, sin mejoría del cuadro clínico, por lo que se decidió la colocación de un balón de oclusión de 34 Fr x 65 cm (Boston Occluder®) junto al catéter vesical, además de nefrostomía percutánea. Se logró disminuir el gasto urinario después de una semana y en la tercera se realizó pielografía anterógrada sin evidencia de fuga urinaria; se le retiró el balón de oclusión y se colocó un catéter doble J, con permanencia del catéter de nefrostomía pinzado y la derivación vesical por catéter transuretral. A seis semanas del procedimiento se retiró el catéter ureteral. Luego de 12 meses de seguimiento se observó el cierre completo de la fístula, los volúmenes urinarios y las concentraciones de azoados se encontraron dentro de los parámetros normales, y no se evidenciaron datos de afectación del injerto renal. CONCLUSIONES: La colocación de un balón de oclusión ureteral, además de nefrostomía, representa una nueva alternativa para tratar pacientes con fístula proximal de alto volumen. PALABRAS CLAVE: Balón de oclusión; fístula urinaria; trasplante renal; tratamiento endoscópico.
Ultrasonido Doppler de pene en la evaluación posterior a prostatectomía radical. Revisión bibliográfica y recomendaciones
Authors: Uribe Juan Fernando , Aluma Luis Javier
Published: December 2020

Changes in sexual function are common in patients following radical prostatectomy for prostate cancer. Sexual rehabilitation after radical prostatectomy requires a complex process in which the diagnosis is refined, and an accurate treatment program is chosen. Penile Doppler ultrasound is a commonly used method for diagnosing erectile dysfunction and it is very useful in certain cases after surgery to improve the assessment of arterial evaluation, venous leaks, and quality of the cavernous tissue and fascia. A literature search was conducted using the databases from Google and PubMed to identify original and review articles that examined the uses of penile Doppler ultrasound in post-radical prostatectomy evaluation or post-surgery rehabilitation. Search terms included: Erectile dysfunction post radical prostatectomy, sexual function post radical prostatectomy, Penile evaluation post-prostatectomy, Diagnosis of erectile function after radical surgery, Penile Doppler ultrasound AND prostatectomy, Penile Doppler ultrasound AND sexual rehabilitation. The initial search resulted in 415 articles. After applying additional filters, 46 studies were included in the present review. Backgrounds of the most relevant guidelines were cited: Standard practice in sexual medicine, Standard operating procedure in sexual medicine, International Consultation on Sexual Medicine, and the EAU and AUA guidelines. Information on the use of penile Doppler ultrasound before surgery is extremely inconsistent in the literature. The recommendations for a successful evaluation of post-radical prostatectomy patients were included. Sexual rehabilitation after radical prostatectomy requires a complex process. There is great inconsistency in the literature with respect to the definition of what is considered normal erectile function before surgery and what may be considered normal erection after radical prostatectomy. The cost of penile Doppler ultrasound is a modest component of the penile post-radical prostatectomy rehabilitation process. Current evidence does not support the systematic use of penile Doppler ultrasound, but it must be included in the management algorithm of the patient undergoing radical prostate surgery so that erectile function can be properly evaluated. KEYWORDS: Prostate cancer; Sexual Dysfunction; Erectile dysfunction; Sexual rehabilitation; Penile Doppler ultrasound; Radical Prostatectomy.
Enucleación transuretral con energía bipolar en el tratamiento de la hiperplasia prostática obstructiva
Authors: Martínez Alonso Iván Azael , Estrada Carrasco Carlos Emmanuel , Torres Gómez Jesus Javier , Hernandez Palacios Gustavo Armando , Padron Lucio Sanjuan , Valdez Flores Rafael Alberto , Martínez Juarez Noe Esaul , Ayala Careaga Daniel , Gorostieta Lujan Janette , Campos Salcedo José Gadú
Published: December 2020

ANTECEDENTES: La enucleación prostática con energía bipolar puede ser una alternativa efectiva a la técnica de enucleación con láser de holmio en pacientes con adenomas de gran tamaño.OBJETIVO: Evaluar la eficacia y seguridad de la enucleación prostática con energía bipolar en pacientes con hiperplasia prostática obstructiva.MATERIALES Y MÉTODOS: Estudio retrospectivo, observacional, analítico y descriptivo efectuado en pacientes con indicación relativa y absoluta de tratamiento endourológico para hiperplasia prostática. Se analizaron parámetros pre y posoperatorios (seis meses) como: IPSS, calidad de vida (QoL), volumen prostático, concentración de antígeno prostático específico (APE), volumen vesical pre y posmiccional, y flujo urinario máximo (Qmax). Características perioperatorias: tiempo quirúrgico, tejido prostático enucleado, tejido enucleado por unidad de tiempo (g/min), tiempo de hospitalización y de cateterización. Para el análisis estadístico se utilizó el programa Excel y SPSS.RESULTADOS: Se registraron 30 pacientes. La indicación más común de cirugía fue retención aguda de orina (56%) y resistencia al tratamiento farmacológico (40%). La media del IPSS fue 22.72 ± 7.65 y volumen prostático 92.97 ± 68.61; concentración de antígeno prostático específico 6.4 ± 4.38 ng/mL, tiempo quirúrgico 113.97 ± 52.1 min y tejido prostático enucleado 65 ± 56.5 g. La eficacia de la enucleación-resección fue de 0.59 ± 0.35 g/min, tiempo promedio de hospitalización 4.3 días y de cateterización posoperatoria 3.4 días. A seis meses de seguimiento no se reportó retención aguda de orina; la media de antígeno prostático fue 1.6 ± 0.7 e IPSS 4.8 ± 2.1. Solo dos pacientes tuvieron incontinencia urinaria de esfuerzo leve.CONCLUSIÓN: La enucleación prostática con energía bipolar es una técnica alternativa efectiva y segura en pacientes con hiperplasia prostática obstructiva.PALABRAS CLAVE: Enucleación prostática; enucleación con energía bipolar; hiperplasia prostática benigna.
Além do direito da liberdade: uma análise republicana da teoria democrática crítica de A. Honneth
Authors: Olivares Nicolás Emanuel
Published: December 2020

No início da década de 2010, A. Honneth delineou uma concepção democrática crítica específica baseada em um modelo social de liberdade individual, que ele considera superior aos modelos negativos e reflexivos. Honneth considera que a democracia deliberativa depende normativamente e empiricamente do modelo social de liberdade individual, de modo que, se certas condições sociais não são cumpridas, os cidadãos carecem das condições que lhes permitiriam a participação na construção da vontade democrática. Neste trabalho, procederemos à reconstrução dos principais postulados normativos da concepção democrática crítica de Honneth, que define positivamente a justiça como reconhecimento mútuo, contrastando-os especularmente com os da concepção republicana defendida pelo filósofo P. Pettit, que se baseia em um modelo negativo de liberdade política entendida como não-dominação. Em resumo, explicaremos quatro atrações comparativas que a teoria de P. Pettit oferece em relação a Honneth em matéria da metodologia, conceito da justiça, classificação de modelos da liberdade, e prioridade da justiça.
O terraplanismo e o apelo à experiência pessoal como critério epistemológico
Authors: Marineli Fábio
Published: December 2020

Movimentos negacionistas vêm ganhando destaque nos últimos anos, disseminados principalmente pelas mídias sociais. A crescente receptividade às suas ideias, assim como a notícias com conteúdos inverídicos, pode ser apontada como indício de uma crise epistemológica relacionada à perda de confiança nas instituições fundamentais da sociedade, na ciência inclusive. As pessoas descrentes nessas instituições tornam-se cada vez mais dependentes das próprias experiências e crenças, até mesmo para avaliar aquilo que se encontra no campo científico. Neste trabalho abordamos uma das características do movimento terraplanista atual: o apelo à experiência pessoal como critério epistemológico incontestável. Para tanto, apoiamo-nos sobretudo nas discussões desenvolvidas por Alfred Schutz relacionadas a formas de experienciar a realidade, seja no campo cotidiano, seja no científico. Identificamos nas concepções terraplanistas modos de caracterização da realidade que são típicos do campo cotidiano, mas acentuados e extrapolados para o contexto científico, em especial para avaliar o formato da Terra e seu movimento. Apresentamos, ainda, exemplos de ideias expressas por adeptos do terraplanismo que apontam para essa direção. Consideramos importante que professores de ciências se apropriem do fenômeno recente da crescente disseminação de movimentos negacionistas e anticientíficos, buscando compreender suas características e discuti-las com estudantes, principalmente sob o ponto de vista epistemológico, esclarecendo seus critérios simplificadores e limitantes.
Polyharmonic Decomposition of a Digital Image
Authors: Markovsky A.
Published: December 2020

A decomposition of the space L2(Q) into a direct sum of polyharmonic subspaces is obtained. The completeness of shift systems of the fundamental solution of the polyharmonic equation is proved. A convergent algorithm for solving the problem of separating the polyharmonic component of a function from L2(Q) is developed. The resulting decomposition is applied to some digital image processing problems; the results of computational experiments are presented.
Effect of ethanolic seed extract of Caesalpinia bonducella on Mifepristone induced PCOS rats
Authors: Balasubramanian Meera , Palayyan Muralidharan , Rajeswary Hari
Published: December 2020

Introduction and Aim: PCOS is a complicated endocrinopathy of women in reproductive age with unknown etiology causing ovulatory dysfunction and metabolic disturbances. The present study investigated the effects of ethanolic seed extract of Caesalpinia bonducella (ESECB) in a mifepristone model of polycystic ovarian syndrome, which has the same clinical and metabolic features as in PCOS women.

Materials and Methods: A daily administration of mifepristone (4mg/kg b.w.) to female rats for 8 days induces PCOS by indicating persistent estrous cycle. PCOS induced rats were treated with ESECB 200mg and 400mg/kg b. w. per oral for 28 days and at the end, the weight of the body and reproductive organs were determined. Biochemical parameters were also estimated. Metformin was used as a standard drug.

Results: A significant increase (p<0.01)in the weight of the body and reproductive organs as well as hyperglycemia and dyslipidemia were observed in the PCOS induced animals, which were reduced considerably in the ESECB drug treated animals. Among two concentrations the animals which received 400mg/kg b. w. of ESECB drug showed significant effect when comparable to the animals which received 200mg/kg b. w. of ESECB.

Conclusion: Based on these observations the ethanolic seed extract of Caesalpinia bonducella (ESECB) can be used as a potential drug in the management of PCOS.
Anti-proliferative effect of Oyster mushroom, Pleurotus from Florida (misnomer) P. florida (Agaricomycetes) against HeLa and SIHA cervical cancer cells: Mushroom-boon for cancer therapies
Authors: Pathak Ravi Kant , Singh Deepika , Gupta Krishna Kumar , Maurya Shweta
Published: December 2020

Introduction and Aim: Worldwide, people are suffering from the increased risk of cancer due to change in lifestyle, feeding habit and quality of food. To overcome this global problem, Mushroom act as a magic wand. The recent investigations reveal that cancer prevalence is inversely proportional to the intake of mushroom; this is because of its proteins, vitamins, carbohydrate and antioxidants contents.

Materials and Methods: Among various species of mushrooms, Pleurotus mushrooms are considered as nutraceuticals i.e. it has nutritional and medicinal values. However, mushroom products and extracts possess immunomodulating and direct cytotoxic effect on cancer cells.

Results: The results from the present study shows the potential cytotoxic effect of Pleurotus from Florida against cervical cancer (SIHA) cell line through apoptosis. When SIHA cells were incubated with varying concentration of methanolic extract of Pleurotus from Florida for time (48 hrs). The MTT assay revealed the cytotoxic activity of MME of Pleurotus from Florida in a dose dependent manner. The cell cycle analysis of the SIHA cells revealed that MME of Pleurotus from Florida have anti-cancerous activity.

Conclusion: The study could be concluded as the Pleurotus from Florida extract can be useful in the treatment of cervical cancers. The chemical compounds present in the P. from Florida might be useful in the development of drug for the treatment of cancer patients.
[entre] outros possíveis
Authors: Cavalcanti Virginia , Porto Filho Gentil , Medeiros de Araújo Kátia
Published: December 2020

Desde 1972 a área de Design está presente na Universidade Federal de Pernambuco. No entanto, o Departamento de Design [dDESIGN] foi criado apenas em 1997, sendo o seu grupo de professores oriundos dos departamentos de Desenho e de Teoria da Arte e Expressão Artística do Centro de Artes e Comunicação. Tais departamentos foram, no passado, responsáveis pelos cursos de Desenho Industrial e suas habilitações em Programação Visual e Projeto do Produto. Atendendo à imensa demanda e, enfim, reunindo condições de maturidade do corpo docente, produção acadêmica e infraestrutura, foi criado em 2004 o Programa de Pósgraduação em Design da UFPE [PPGDesign UFPE] com o curso de Mestrado Acadêmico em Design stricto sensu, o terceiro no Brasil. Junto às especializações lato sensu em Design da Informação e em Ergonomia, o Mestrado Acadêmico em Design da UFPE passou a formar pesquisadores capacitados à docência nas instituições de ensino superior que à época surgiam no Norte e Nordeste do país. Já o curso de Doutorado, foi criado em 2010 como decorrência natural da qualidade do curso de Mestrado e da expansão das atividades de pesquisa potencializadas pelo programa no dDesign.
Justice in climate change adaptation planning: conceptual perspectives on emergent praxis
Authors: Fünfgeld Hartmut , Schmid Benedikt
Published: December 2020

Abstract. The measures implemented to adapt to climate change are primarily designed to address the tangible, biophysical impacts of climate change in a given geographic area. They rarely consider the wider social implications of climate change, nor the politics of adaptation planning and its outcomes. Given the necessity of significant investment in adaptation over years to come, adaptation planning and implementation will need to place greater concern on justice-sensitive approaches to avoid exacerbating existing vulnerabilities and creating maladaptive and conflicting outcomes. Building on recent calls for more just and transformative adaptation planning, this paper offers a flexible analytical framework for integrating theories of justice and transformation into research on climate change adaptation. We discuss adaptation planning as an inherently normative and political process linked to issues pertaining to recognition justice as well as distributional and procedural aspects of justice. The paper aims to contribute to the growing discussion on just adaptation by intersecting theoretical justice dimensions with spatial, temporal and socio-political challenges and choices that arise as part of adaptation planning processes. A focus on justice-sensitive adaptation planning not only provides opportunities for examining spatial as well as temporal justice issues in relation to planning and decision-making processes. It also paves the way for a more critical approach to adaptation planning that acknowledges the need for institutional restructuring and offers steps towards alternative futures under climate change conditions.
The influence of chosen organic fertilizers on qualitative parameters of three Daucus carota L. varieties
Authors: Golian Marcel , Hlavačková Lucia , Maťová Adriána , Mezeyová Ivana , Šlosár Miroslav , Hegedűsová Alžbeta , Adamec Samuel
Published: December 2020

In rational nutrition, vegetables play an important role due to their high biological and low energy value. The most widespread vegetables in our country belong to root vegetables. They are grown mainly for bulbs, corms, rhizomes, fleshy roots, and hypocotyl tubers. Root vegetables can be eaten raw or cooked. Carrot (Daucus carota L.) is a basic representative of root vegetables. For the most valuable components counts beta-carotene – the major component of total carotenoids. This paper evaluates changes in total carotenoids, refractometric dry matter, and gravimetric dry matter in three varieties of carrot (Kamaran F1, Komarno F1, Romosa) grown in soil and climatic conditions ex-situ in Nitra. We have evaluated roots grown in non-fertilized soil, soil after application of manure, horticultural compost, and their combinations. The results show that the variants fertilized with compost and a mixture of compost and manure had the most considerable influence on the synthesis and content of total carotenoids as well as the content of dry matter and refractometric dry matter
Asia-Pacific initiative for rheumatology nurse education: An impact survey in China
Authors: Oliver Susan , Bradbury Linda , Mu Rong , Wang Xiaobing , Furtner Daniel
Published: December 2020

Background/Objective: Asia-Pacific Initiative for Rheumatology nurse Education (ASPIRE) is a faculty-led initiative established to meet the educational needs of rheumatology nurses in Asia Pacific in recognition of the expanding role of nurses in daily rheumatology clinical practice. The objective of this study is to measure the impact of ASPIRE workshop training on nurses’ levels of knowledge, confidence, attitudes and beliefs using a Before-after-control-impact (BACI) survey.Methods: A total of 210 nurses who completed both pre- and post-surveys were included in the BACI analysis. The intervention group (n = 111) refers to nurses who attended the ASPIRE workshop training held during the China Chronic Disease Management Forum in Baotou, Inner Mongolia in September 2019 whereas the control group (n = 99) refers to Chinese nurses that have never attended the ASPIRE training. Results: Overall level of knowledge significantly increased by 30% (5.63 pre- vs. 8.34 post-survey; p < .001), and overall level of confidence significantly increased by 29% among nurses who attended ASPIRE training (5.83 pre- vs. 8.39 post-survey; p < .001). Nurses in the control group demonstrated no significant increase in knowledge (6.18 pre- vs. 6.50 post-survey; p = .097) or confidence (6.46 pre- vs. 6.71 post-survey; p = .169) over the same period.}Conclusions: Nurses who attended the ASPIRE training workshop reported a significant increase in their levels of knowledge and confidence compared with a control group of nurses who have never undergone ASPIRE training. Training rheumatology nurses to acquire more in-depth knowledge and skills can help optimize their role in clinical practice to meet the greater demands of disease monitoring and long-term management of rheumatology patients.
Análise experimental de indicadores de qualidade de energia de lâmpadas LED E27 residenciais disponíveis no mercado brasileiro
Authors: Aguiar Junior Edsio Alves de , Stoller Henrique Castro , Scofield Phillipe Stoller
Published: December 2020

With advances in energy demand, investments in energy efficiency and power quality are increasingly important. One of the extensively adopted measures is the replacement of fluorescent lamps by LED lamps. This measure contributes to the increase of energy efficiency, but produces a high load of current harmonics, which may cause degradation in power quality indicators of the electric distribution networks, due to the presence of rectification electronic circuits present in such lamps. In this work, several models of LED lamps available in the Brazilian market were tested for harmonic and power factor production, taking as reference the standards Inmetro 389/2014, 143/2015 and 144/2015. Applying the Fast Fourier Transform (FFT) the modules and phases of each harmonic component in the currents were measured. Subsequently, the total harmonic distortion (THD) of the current in each lamp was calculated and the estimated total power factor. The results obtained were compared with the nominal values of the lamps and the circuit of four of the lamps was analyzed. It was verified that only six models out of the twenty-three analyzed had THD below 100% and of the analyzed models, 61% did not meet the nominal technical specifications regarding the power factor, and that Power Factor Correction (PFC) techniques present in some of the models were responsible for adjusting the lamps to the regulation parameters.
Desempenho de misturas asfálticas recicladas mornas e sua influência no dimensionamento do revestimento asfáltico
Authors: Gadler Fernanda , Miranda Leonardo Fagundes Rosemback , Villena Joe
Published: December 2020

The main purpose is to evaluate the performance of asphalt regarding resilient modulus and fatigue curve.The asphalt was produced with two wastes, reclaimed asphalt pavement (RAP) and recycled concrete aggregate (RCA), using the technique of warm mixtures. The evaluation includes, based on these parameters, the thickness differences in the design of asphalt layer for each mixture. Five asphalt mixtures were produced with incorporation of RAP and RCA, in different gradation fractions (fine and/or course), without adding any natural aggregate. In view of the aim of the article, the mixtures were evaluated through tests of resilient modulus and fatigue life, in order to support the design, establishing the necessary thickness to meet traffic demands of each mixture. The design was performed using MeDiNa software. Among all results, it is highlighted that asphalt binder content is the component that exerts the greatest influence on the resilient modulus of the mixtures. As for fatigue, in addition to the binder content, the possible anchoring of the asphalt binder in the pores of the RCA may have favored the performance of the GARC_MRAP mixture. Still, all mixtures with RAP, both in fine or course fraction, resulted in lower coating thicknesses compared to the REF, for the same load request, with better performance of the GARC_MRAP mixture produced with 100 % waste material and incorporation of only 3.1 % neat binder.
Case – Reflex anuria: A rare complication of retrograde pyelography
Authors: Dharia Atit , Sridhar Vikas , Perlis Nathan , Cherney David
Published: December 2020

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A influência do utilitarismo e do hedonismo no consumo de carne ovina: um estudo em região produtora do sul do Brasil
Authors: Borges Sávio Costa , Borges Gustavo Da Rosa , Viana João Garibaldi Almeida
Published: December 2020

Objetivo:  O presente trabalho teve como objetivo analisar a influência do utilitarismo e do hedonismo no consumo de carne ovina em região produtora do estado do Rio Grande do Sul, Brasil. Ainda, buscou-se construir cenários para estimar a probabilidade de aumento do consumo de carne ovina em função de variáveis hedônicas e utilitárias.Método: O estudo possuiu um caráter explicativo de abordagem quantitativa. O método utilizado foi o Survey, por meio de questionário estruturado aplicado a uma amostra de 193 consumidores de carne ovina. O instrumento de pesquisa foi constituído de variáveis sociodemográficas, de frequência de consumo de carne ovina, de quatro variáveis referentes ao utilitarismo e de quatro variáveis referentes ao hedonismo. A análise dos dados ocorreu por estatística descritiva e multivariada.Originalidade/Relevância: O estudo trouxe contribuições acerca dos hábitos de consumo de carne ovina em uma região caracterizada por essa produção, focando a percepção utilitária e hedônica ao consumir esse tipo de carne.Resultados: As evidências da pesquisa indicam que comportamentos utilitários e hedônicos podem contribuir para um consumo mais frequente de carne ovina, especialmente as variáveis hedônicas que demonstraram maior influência.Contribuições teóricas/metodológicas: Como contribuição científica, percebeu-se que mesmo produtos considerados básicos para o consumo podem proporcionar hedonismo, o que demonstra a possibilidade de agregar valor a bens de primeira necessidade.
Nowe zasady stosowania badań nieniszczących do oceny wytrzymałości
i jednorodności betonów. Cz. 1.
Authors: Runkiewicz Leonard , Runkiewicz Maciej , Sieczkowski Jan
Published: December 2020

W artykule opisano nowe zasady oceny wytrzymałości betonu na podstawie badań metodami nieniszczącymi. Zasady te, określone w normie PN-EN 13791, są odmienne od dotychczas stosowanych według PN-B. Niemniej jednak możliwe jest dalsze stosowanie krzywych korelacji wykorzystywanych w dotychczasowej praktyce budowlanej. Za tym przemawiają małe różnice w wartościach wytrzymałości betonu określanych według PN-EN i PN-B.
Der Einfluss der Digitalisierung auf das Preismanagement – Ansatzpunkte, Modelle und Methoden
Authors: Roll Oliver , Loh Patrick
Published: December 2020

Die Digitalisierung führt zu einer Zunahme von digitalen Angeboten, zu einer verbesserten Datenverfügbarkeit und zu neuen Ansätzen im Preismanagement - dieses betrifft vor allem die Verwendung von Daten sowie die Anwendung von Software und künstlicher Intelligenz im Pricing. Dadurch beeinflusst die Digitalisierung die grundsätzlichen Ansatzpunkte, Modelle und Methoden im Preismanagement und erzeugt gleichzeitig neue Möglichkeiten und Chancen. Dieser praxisorientierte Beitrag legt ausgewählte Facetten des Einflusses der Digitalisierung auf das Preismanagement offen und zeigt Handlungschancen und -notwendigkeiten auf. Darauf aufbauend werden relevante Schlussfolgerungen für die Praxis des Preismanagements abgeleitet.
Improving pricing scope through consumers’ construal level – evidence based on consumers’ willingness-to-pay ranges
Authors: Isaak Karina , Wilken Robert , Dost Florian , Bürgin David
Published: December 2020

How can the pricing scope be further leveraged in times of increased price transparency and growing price awareness on the consumer side? To answer this question, this paper uses the concept of willingness-to-pay ranges (as opposed to points). Three quantitative studies show that various marketing activities that allow consumers to assess a product on a more abstract (less concrete) level shift the upper limits of the intervals upwards and thus increase the scope for price setting. These (price) upper limits are particularly high when the central product advantages are emphasized.
Religija
Authors: Ragaz Stefan
Published: December 2020

This book analyzes the Russian 19th-century discourse on the Orient as a field where the conceptual foundations of contemporary understandings of religion evolved. In case studies on the reception of Islam, Zoroastrianism, Buddhism, and Shamanism with a focus on the first half of the century it traces the formation of key terms and concepts of the language that served to describe religions. Of special interest are the emergence of generic concepts of religion and the history of the term ‘religion’. The study draws on sources from genres such as Oriental Studies, literature, travelogs, and journalism. With its interdisciplinary perspective it contributes to Religious Studies, Russian Studies, and the cultural history of the Russian Empire.
Mental Distress among Medical Students
Authors: Rubaba Azim Syeda
Published: December 2020

Depression, anxiety, and stress affect the mental health of an individual. Previous studies have shown high rates of depression, anxiety, and stress among medical students throughout the world. Medical students are future doctors, but mental distress among them has negative effects on their output, which ultimately affects patient care and quality of life. This chapter will discuss various reasons of mental distress among medical students and proposed solutions for the well-being of medical undergraduates like providing proper student support service and more opportunities for extracurricular activities.
Electrochemical, Thermodynamic, Surface, and Spectroscopic Study in Inhibition of Iron Corrosion with Turmeric Root Extract (TRE)
Authors: Almzarzie Khuloud , Almassri Ayman , Falah Ahmad , Kellawi Hassan
Published: December 2020

Turmeric root extract was tested as corrosion inhibitor for iron in 0.5 M HCl, using potentiodynamic polarization and electrochemical impedance spectroscopy, scanning electron microscope, and energy dispersive X-ray analysis. The inhibition efficiency increases as the time of immersion rises but decreases with temperature rise. The Nyquist plots showed that the charge transfer resistance increases and the double-layer capacitance decreases as the time of immersion increases. Tafel results show that both corrosion current and corrosion speed are reduced with time of immersion. All impedance spectra of EIS tests exhibit one capacitive loop, which indicates that the corrosion reaction is controlled by charge transfer process. Inhibition efficiency increases with the concentration of the inhibitor reaching its maximum value, 88.90%, at 8 g/100 mL. Thermodynamic parameters, Ea, ∆H*, and ∆S*, were estimated, and the mechanism of corrosion and inhibition was discussed. The adsorption of turmeric root extract followed Langmuir adsorption isotherm.
An Econometric Investigation of Market Volatility and Efficiency: A Study of Small Cap’s Stock Indices
Authors: Jawad Muhammad , Naz Munazza
Published: December 2020

By utilization the context of econometric models, this chapter investigates three significant research parameters and tries to find out the positive outcome for further studies. The first question, is the volatility of Small Cap foreseeable?. The second question, does the volatility of Small Cap exhibition the same pragmatic regularities stated in the literature about the behavior of further stock prices?, The third and Final question, can Small Cap clear the test of market efficiency?. The results of these research questions will provide the answers of following objectives: First, economic representatives investing in Small Cap Stock markets. Second, the business professors/professionals/educationist is more concerned in Small Cap for their teaching and research. Third, the policy makers who are observing the stock market volatilities because of its significances and impulsive behavior to invest for more incentives among other consequences.
The New Challenges for Medical Ethics
Authors: Lorettu Liliana , Aubut Jocelyn , Ciliberti Rosagemma
Published: December 2020

The evolution of medicine confronts healthcare professionals with new ethical challenges. Elements such as professional secrecy, patient benefit, justice in the distribution of resources are put in crisis by the evolution of medical procedures. Today, doctors must make life-and-death decisions about many patients. As the resources are not enough for all patients, the ‘first-come, first-served’ criterion crumbles under the weight of the overwhelming demand for treatment. Consequently, they can no longer make treatment decisions based only on proportionality and clinical appropriateness criteria. They must take into account the availability of resources and prioritise patients with ‘the longer life expectancy’. This amounts to saying ‘the weakest will die’ … with the doctors’ consent. While the guidelines issued by scientific societies may well protect doctors from lawsuits, the choice of who to treat and who to let die is left to the conscience of the individual doctor; and it is a choice sharply clashing with the Hippocratic oath and with professional and personal ethics. This and others are a real ethical problem.