bluuebunny/crossref_metadata_2025 huggingface dataset:
Pelatihan Praktik Pertanian Organik Tanaman Lada (Piper nigrum L.) Melalui Penggunaan Biokompos
Authors: Rini Maria Viva , Hidayat Kuswanta Futas , Evizal Rusdi , Ramires Ryano , Jannah Husna Fii K
Published: February 2025

Lampung merupakan sentra produksi lada di Indonesia setelah Bangka dikenal dengan nama Lampung Black Paper, salah satu sentra produksinya adalah di Kecamatan Air Naningan, Kabupaten Tanggamus. Namun, akibat penggunaan pupuk kimia dan pestisida serta adanya keparahan serangan penyakit busuk pangkal batang menjadikan produksi lada di Kabupaten Tanggamus mengalami penurunan. Salah satu cara untuk peningkatan produksi lada yakni penerapan perkebunan organik dengan pemanfaatan biokompos. Pelatihan penerapan biokompos dilakukan di Kelompok Tani Makmur Jaya dengan jumlah anggota sebanyak 21 petani. Kegiatan terdiri dari ceramah dan diskusi mengenai biokompos, varietas lada, serta budidaya lada organik. Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan petani tentang biokompos. Berdasarkan data pre-test dan post-test, dapat dilihat bahwa pengetahuan petani tentang bikompos telah meningkat sebesar 51,35%. Kemudian petani diberikan pengetahuan praktek langsung di kebun dengan tujuan memberikan pengetahuan langsung kepada petani tentang teknik aplikasi biokompos. Petani melakukan praktek dengan cara menanam 6 bibit diberi biokompos dan 6 bibit tanpa biokompos. Data awal 2 bulan setelah aplikasi menunjukkan bahwa perlakuan biokompos belum menghasilkan tinggi bibit yang berbeda nyata dengan kontrol. Peningkatan pertumbuhan bibit diperkirakan akan tampak pada 6 bulan setelah aplikasi.
Al-Andalus en la geografía imaginaria del persa al-Qazwīnī (s. XIII)
Authors:   Universidad de Sevilla (España), Roldán Castro Fátima
Published: February 2025

The Persian scholar al-Qazwīnī authored the Kitāb āṯār al-bilād wa ajbār al-ʿibād in the 13th century, an encyclopedic work that pays special attention to the Andalusian territory. Al-Qazwīnī explored this region from an Eastern perspective, drawing on accounts from earlier authors and describing more than thirty cities. In his depiction, he notably employed the genre dedicated to the representation of wonders or ʿajāʾib. This study examines the cultural and literary context of his work, the genre that defines it, and the marvelous stories that shape his narrative. It presents an imaginative geography centered on a land of cities abundant in water, natural wealth, and landscapes of exceptional productivity and beauty
A STUDY OF TRANSGENIC ALFALFA PLANTS (MEDICAGO TRUNCATULA GAERTN.) PRODUCING CHICKEN INTERFERON-GAMMA
Authors:   Saint Petersburg State University, Chernov K.P. , Burlakovsky M.S. , Okulova E.S. , Agliullina D.R. , Padkina M.V. , Lutova L.A.
Published: February 2025

In modern pharmacology, there is a transition from low-molecular-weight drugs to protein drugs, which are obtained using
transgenic producing organisms. Using the example of gamma interferon producing plants, we demonstrate the advantages and disadvantages of the plant expression system, and methods to increase its effectiveness.
THE USE OF AMINO-CONTAINING CATALYST FOR OPENING THE OXIRANE RING IN “POLYMER BRUSHES” MADE FROM GLYCIDYL METHACRYLATE IN PROTEIN BIOCHIP TECHNOLOGY
Authors:   Engelhardt Institute of Molecular Biology RAS, Moscow, Shtylev G.F. , Kachulyak D.A. , Zasedateleva O.A. , Chudinov A.V.
Published: February 2025

According to the immobilization of the fluorescent dye, amine-based catalysts were selected to open the oxirane cycle in polymer
brushes made of glycidyl methacrylate attached to the surface of polybutylene terephthalate. Immobilization of a protein labeled with fluorescent dye Cy3 was performed to test polymer brushes on a real model for the use of the chip in immunochemical analysis of antibodies.
RECENT ADVANCEMENTS IN COARSE-GRAINED SIMULATIONS OF BIOMOLECULAR SYSTEMS
Authors:   Shenzhen MSU-BIT University, China, Bozdaganyan M.E. , Orekhov P.S.
Published: February 2025

Over recent decades, computer simulations of proteins and other biological molecules have become a powerful tool, providing
high-resolution insights into the dynamics of biological systems. The demand for simulations on larger time and length scales has led to
the development of coarse-grained techniques, which simplify models by substituting groups of atoms with single particles, or ‘beads’.
These methods enable comprehensive exploration of complex phenomena, such as membrane dynamics and protein interactions, while
reducing computational costs compared to all-atom simulations. This talk will highlight recent advancements in coarse-grained simulations, illustrated by diverse examples and discuss the limitations and challenges of popular coarse-grained models, proposing potential
strategies for improvement.
DEVELOPMENT OF LIPID NANOPARTICLES BASED ON APOLIPOPROTEIN MIMETICS AND CHOLESTEROL DERIVATIVES FOR SMALL INTERFERING RNA DELIVERY
Authors:   Institute of Biophysics and Cell Engineering NAS of Belarus, Minsk, Abashkin V.M. ,   Korea Institute of Science and Technology, Seoul,   Institute of Physical Organic Chemistry NAS of Belarus, Minsk, Zhogla V.A. , Ihnatsyeu-Kachan O.A. , Sharko O.L. , Shmanai V.V. , Shcharbin D.G.
Published: February 2025

Delivery of small interfering RNA using biocompatible nanostructures is a promising approach for genetic therapy of cancer.
In our work, we have developed approaches to create lipid nanostructures based on cholesterol and spermine derivatives with apolipoprotein.
THE POSSIBILITY OF PHOTOCONTROL OF ACID-SENSING ION CHANNELS
Authors:   Sechenov Institute of Evolutionary Physiology and Biochemistry RАS, Saint Petersburg, Gataulina E.D. , Nikolaev M.V.
Published: February 2025

In this work, we investigated the effect of an azobenzene-containing polyamine on the acid-sensing ion channel (ASIC1a).
The compound inhibited the ion channels under room light condition, but irradiation with blue light restored currents. Thus, we have
discovered the possibility to control ASIC1a using photochromic ligands. This finding is of great importance for the development of
new light-controlled tools to study the role of these channels in the CNS.
STUDY OF GROWTH OF HUMAN OVARIAN ADENOCARCINOMA CELLS LINE SKOV-3 IN ACELLULAR MATRICES OF MOUSE ORGANS WITH DIFFERENT STRUCTURAL AND MECHANICAL CHARACTERISTICS
Authors:   Lobachevsky State University of Nizhny Novgorod, Gefter S.D. ,   Sechenov First Moscow State Medical University,   Federal Research Center “Crystallography and Photonics” RAS, Moscow, Pospelov A.D. , Trushina D.B. , Efremov Yu.M. , Karpushin M.Yu. , Balalaeva I.V.
Published: February 2025

The paper analyzes the growth characteristics of human ovarian adenocarcinoma cells of the SKOV-3 line in cell-free matrices
of mouse organs. It is shown that the ability of tumor cells to populate tissue depends on the structural and mechanical parameters of
the matrix. In particular, the greatest cell growth was observed in matrices with low stiffness of the three-dimensional structure and
large pore size.
ICE CRYSTAL FORMATION IN CRYOPROTECTIVE MEDIA UNDER VARIOUS FREEZING REGIMES
Authors:   Lomonosov Moscow State University, Ivanova A.A. , Simonenko E.U.
Published: February 2025

Despite numerous studied of the cryopreservation process the percentage of cell survival remais low. The work is devoted to
the study of the process of ice crystal formation in cryoprotective media under various freezing regimes. A new method for diffraction
patterns analysis as well as alternative mode of cell freezing regime during cryopreservation is proposed.
Gender, education, eating patterns, and nutritional status among high school students in the tourist area of Bukittinggi, Indonesia
Authors: Taufiqa Zuhrah , Maisa Benny Alexander , Zam Zelly Salmiyanti Rahman , Ranza Fathiya Rizqillah , Alem Najla Khalisha , Amril Farah Alya
Published: February 2025

Background: The well-being of high school students in tourist shapes their eating habits and affects their nutritional status, leading to obesity and malnutrition.
Objective: This study aims to examine the association between gender, education, eating patterns, and nutritional status among high school students in tourism areas.
Methods: This cross-sectional study was conducted in October 2023 and included 118 students aged 12–18 years from junior and senior high schools in Bukittinggi, West Sumatra. Respondents were selected through multistage stratified clustered sampling. Data on gender, age, education, and eating patterns which assessed using a food frequency questionnaire classified according to the Guttman scale. Nutritional status was determined based on BMI-for-age WHO z-scores following the Indonesian Minister of Health Regulation. Data were collected via interviews using a questionnaire on the KoboToolbox application and analyzed using Chi-square tests.
Results: Most high school students (89.8%) had poor eating patterns, with 45.8% having a normal BMI-for-age, 34.7% undernourished, and 19.5% overweight or obese. Gender was significantly associated with nutritional status (p=0.007), with thinness more common in boys and normal BMI-for-age more prevalent in girls, while education and eating patterns showed no significant association. However, frequent consumption of sugary drinks was linked to higher rates of overweight and obesity.
Conclusion: There were gender differences in nutritional status among high school students in Bukittinggi, a tourist area, underscoring the need for targeted gender-focused nutrition interventions to address healthier eating patterns in tourism regions.
Identification of testis derived differentially expressed spermatogenic microRNAs in idiopathic hypospermatogenesis
Authors: Sharma Nisha , Halder Ashutosh , Kaushal Seema , Kumar Manoj , Jain Manish
Published: February 2025

Objectives

Hypospermatogenesis (HS) is a common histopathological subtype of non-obstructive azoospermia (NOA), characterized by a decrease in the total number of germ cells within the seminiferous tubule. The diagnosis of HS is made by invasive procedures like testicular biopsy or fine needle aspiration (FNA). MicroRNAs (miRs) are biomolecules with emerging roles as diagnostic biomarkers for diseases. This study aimed to investigate the differential miR expression profile in idiopathic HS (iHS) to explore candidate spermatogenic miRs in human male infertility.

Material and Methods

In this observational study, patients reporting azoospermia due to spermatogenic failure were recruited prospectively. Genetic exclusion was performed using XY-fluorescent in-situ hybridization (XY-FISH) and Yq microdeletion. Testicular FNA samples were used for total ribonucleic ccid (RNA) isolation. Small RNA sequencing-based exploratory analysis was performed on 20 iHS patients and five normospermatogenesis (NS) patients. nCounter miRNA expression based validation was performed for four iHS and four NS patients.

Results

Analysis of miRs in testicular tissue showed differential expression patterns having 49 downregulated and 3 upregulated miRs between iHS and NS patients, with miR-379-5p, miR-449a, miR-181c, miR-34b-3p, and miR-122b-5p being notable candidate spermatogenic miRNAs. Pathways such as Phosphatidylinositol 3 Kinase-Protein Kinase B (PI3K-Akt) and mitogen-activated protein kinase (MAPK) signaling and molecular functions like apoptosis and cell differentiation were significantly enriched in iHS patients. This is the first study of its kind to investigate the differential expression of micro-ribonucleic acid (miRs) in a cohort of NOA patients exclusively of the HS subtype. Comparing the study results to previously published data revealed that dysregulated spermatogenic miRs are shared in HS and other NOA subtypes. The analysis of spermatogenic miRs according to each patient’s profile showed significant dysregulation in miR expression, linked to 40% of cases with idiopathic HS.

Conclusion

This study provides important insight into the potential of miRNA to be used as a biomarker for the diagnosis of iHS. Although the study is based on a relatively low sample size, it provides a proof of concept which can be validated in a larger cohort.
¿Cómo afectan las zanjas de drenaje a la disposición espacial de la vegetación deltaica?
Authors: Bazylenko Andriy , Sirolli Horacio , Torrella Sebastián A.
Published: February 2025

El drenaje es una práctica recurrente que permite incorporar los humedales a diversas actividades productivas. Esto conlleva cambios sustanciales en la composición y la diversidad de sus comunidades vegetales. El Delta Frontal del río Paraná es un conjunto de humedales mareales dulceacuícolas, con islas formadas por un albardón periférico y un centro deprimido. La vegetación natural está determinada por la topografía, con bosques en los albardones, pajonales en los interiores y ceibales en sitios intermedios. La actividad productiva principal es la forestación con salicáceas; su desarrollo implicó construir zanjas de drenaje que redujeron la duración de las inundaciones en el interior de las islas. El objetivo de este trabajo fue evaluar si la disposición de la vegetación está condicionada por la presencia de las zanjas de drenaje, además de por la geomorfología. Para ello, se dispusieron 198 parcelas de 25 m2 y se registró la presencia de todas las especies de plantas vasculares, la distancia al arroyo más cercano (como aproximación de su ubicación geomorfológica) y la distancia a la zanja más cercana. Se generaron modelos lineales generalizados para evaluar, para cada parcela, la relación entre estas distancias y dos variables: la ocurrencia de especies características de distintos ambientes del Delta Frontal y la cantidad de especies total y por hábito. Se encontró que en sitios alejados de los arroyos (bajos), la cercanía a las zanjas está asociada a un incremento de especies arbóreas y a la ocurrencia de especies características de los bosques de albardón. Los resultados muestran que la vegetación del Delta Frontal, además de estar condicionada por la geomorfología, está influenciada por la presencia de zanjas de drenaje. Estos elementos amplían la distribución potencial de las mencionadas especies y establecen una nueva configuración espacial de los bosques de albardón.
On the connection between the Exact Factorization and the Born-Huang representation of the molecular wavefunction
Authors: Schürger Peter , Lassmann Yorick , Agostini Federica , Curchod Basile
Published: February 2025

In these Notes we present a new perspective on the exact-factorization expression of a molecular wavefunction, which does not rely of the probabilistic interpretation of the molecular wavefunction as a joint probability amplitude. Instead, we demonstrate a close relation with the traditional Born-Huang representation, as the exact factorization emerges as the representation in the basis the of eigenvectors of the density matrix at nuclear position R. In doing so, the partial normalization condition and gauge freedom arise naturally from the formalism. In a second part, we derive the equation of motion in the here introduced exact factorization basis.
Mechanical, Thermal, and Rheological Properties of Fish-Porcine Gelatin Microparticle Composites for Advanced 3D Biofabrication
Authors: Bokhari Syed M. Q. , Alioglu Mecit A. , Voronin Grace L. , Catchmark Jeffrey M.
Published: February 2025

Driven by the increasing need for the biofabrication of complex hydrogels, this work introduces a class of fish–porcine composite hydrogels that combine rapid, tunable photo-crosslinking with microparticle reinforcement for advanced 3D printing. Here, pre-crosslinked porcine gelatin (methacrylated porcine gelatin, MPG) microparticles are incorporated into a methacrylated fish gelatin (MFG) matrix to produce robust yet easily processable hydrogels. Nuclear Magnetic Resonance (NMR) confirmed the degree of methacrylation, while scanning electron microscopy (SEM) revealed the hierarchical porosity vital for tissue integration. Detailed Mastersizer measurements characterized the size distributions of the MPG microparticles, and rheological tests demonstrated the composite hydrogels’ strong shear-thinning behavior an essential trait for extrusion-based and embedded 3D printing. Thermal (TGA, DSC) and mechanical (compression) analyses show that the microparticle-reinforced hydrogels achieve improved thermal stability, adjustable mass swelling ratio, and customizable compressive moduli. As a proof of concept, these composites are validated in digital light processing (DLP) printing of microfluidic constructs and as a support bath for embedded printing of complex geometries. This platform provides a unique synergy of easy UV crosslinkability, tunable mechanical features, and 3D printing versatility. This advancement underscores the potential of these materials as a foundational platform in tissue engineering, opening new avenues for creating complex, biocompatible structures with customizable properties.
An exhaustive mapping of zeolite-template chemical space
Authors: Xie Mingrou , Schwalbe-Koda Daniel , Semanate-Esquivel Yolanda M. , Bello-Jurado Estafanía , Hoffman Alexander , Santiago-Reyes Omar , Paris Cecilia , Moliner Manuel , Gómez-Bombarelli Rafael
Published: February 2025

Zeolites are industrial catalysts and adsorbents whose synthesis usually employs specific molecules known as organic structure-directing agents (OSDAs). The OSDA’s templating effect is pivotal in determining the zeolite polymorph formed and its physicochemical properties. However, de novo design of selective OSDAs is challenging because of the diversity and size of the zeolite-OSDA chemical space. Here, a computational workflow powered by machine learning enables an exhaustive exploration of the OSDA space for known zeolites. Models were developed to predict molecule-zeolite binding energies and trained on hundreds of thousands of datapoints, the largest ever library of synthetically accessible, hypothetical OSDA-like molecules was enumerated from commercially available precursors, and nearly 500 million zeolite-molecule pairs were screened. From these, two new OSDAs were identified and validated experimentally to template zeolites with unique compositions. The nearly exhaustive scale of the OSDA library and open-access data are expected to accelerate OSDA design for the entire field.
Protecting-group-free synthesis of Lycojapomine alkaloids enabled by radical dearomatization of a pyrrole
Authors: Gross Benjamin M. , Stoltz Brian M.
Published: February 2025

Alkaloids represent one of the most important and largest classes of natural products, that are defined by carrying one or more basic nitrogen atoms. These secondary metabolites have given way to numerous approved drugs and advancements in the medical sciences.1,2 Their preparation in the laboratory remains tedious however, broadly hampered by nitrogen’s nucleophilic nature and susceptibility to oxidation. To address this problem, a large number of protecting groups have been developed over the last decades to temper the reactivity of necessary nitrogen atoms and achieve the synthesis of the corresponding alkaloid.3 This often leads to an increased step-count and synthetic inefficiency, disrupting the further optimization and investigation of their biological properties.4 Here we address this problem, by achieving the synthesis of a class of complex Lycojapomine alkaloids, utilizing a photo-induced radical dearomatization of a pyrrole derivative and a subsequent ionic functionalization cascade. The chemical transformations utilized shape the way for future alkaloid syntheses and showcase the advantages of starting from simple aromatic heterocyclic starting materials, eliminating the need for any protecting groups.5,6
Benchmarking Classical Molecular Dynamics Simulations for Computational Screening of Lithium Polymer Electrolytes
Authors: Ruza Jurgis , Leon Pablo , Jun KyuJung , Johnson Jeremiah , Shao-Horn Yang , Gomez-Bombarelli Rafael
Published: February 2025

Polymer electrolytes may play a crucial role in the development of safe, efficient energy-dense batteries thanks to their unique ability to facilitate ion transport while maintaining structural stability. However, experimental discovery is limited by the complexity of synthesizing and testing new monomer and polymer chemistries. In this study, we benchmark the ability of molecular dynamics (MD) simulations with Class 1 force fields to model the transport and structural properties of polymer electrolytes in a high-throughput screening setting. By systematically comparing simulation results with experimental data for 19 polymers, we evaluate the effect of simulation choices in predicting key transport properties. In particular, we evaluate convergence of diffusivities and conductivities as a function of simulation length, and how inaccuracies in modeling polymer glass-transition temperature carry over to ion transport properties. The results highlight both the strengths and limitations of affordable high-throughput MD simulations for these complex systems, providing insights into the optimization of MD simulations for polymer electrolyte research, and recommendations for modeling choices with optimal cost-accuracy trade-offs. Furthermore, we perform in-depth transport and structural property analysis across the polymer space to gain insights into the design of new polymer electrolytes.
Relationship Between Metabolic Syndrome and Primary Open-Angle Glaucoma: A Systematic Review and Meta-Analysis
Authors: Almishhadany Hashim Sallam , Alkhatib Rita , Al-Zuhairi Ahmed , Aswad Mohamad Khalid Al , Almaliti Donea N. , Mohamed Meryem , Obeng Dr. Joyce Nana Yaa , AlMusallam Rodha Saeed , Alfalasi Shaikha Belhoul , Arif Muhammad Salman
Published: February 2025

Metabolic syndrome (MetS) is a constellation of disorders that, on their own or in combination, pose an increased threat to cardiovascular health, the development of type 2 diabetes, and a number of other chronic diseases. Newer research has proposed a relationship between MetS and some eye disorders, including primary open-angle glaucoma (POAG), which is one of the most common causes of blindness in the world. Yet this relationship remains ill-defined. This meta-analysis aims to evaluate studies that specifically explore the interconnection between MetS and POAG with a particular focus on what pathways MedS may use to alter the development or progression of POAG. Within this meta-analysis, a meticulous selection of the period 2023 - 2025 was used. The choice of studies was also limited to those that were registered in PubMed, Scopus, and Web of Science. The analysis included studies examining MetS components such as hypertension, hyperglycemia, dyslipidemia, and HO and their relation to POAG. Data retrieval was performed on cross-sectional and cohort studies in order to capture a broader view of phenomena from various perspectives. Study quality assessment was performed by applying bias and methodological quality tools. As revealed from this report, diabetes and hypertension appear to be the leading reasons for more chances of individuals with MetS developing POAG. Moreover, specific components of MetS, such as insulin resistance and hypertension, could be essential when it comes to the causes of POAG. Further studies are needed to understand why there are varying results from different studies and how confounding factors may impact the results obtained. This study strongly indicates a relationship between MetS and POAG. This analysis reveals the need for MetS at an early stage to prevent the onset of POAG. Larger scale studies examining more subjects are needed to determine the factors that lead to this correlation and appropriate interventions to treat them.
Life is Programmed Computation
Authors: Lynn Abel David
Published: February 2025

All known life is:

Multi-dimensionally programmed
Instructed by Functional Informational
Representationally symbol-system prescribed
Coded
Transcribed and translated
Successfully cybernetically processed (“halts”)
Is literally computed
Algorithmically orchestrated
Processed by ingeniously integrated circuits

These are all formal concepts, not mere mass/energy interactions. Thus, life is fundamentally abstract, conceptual and formal. Its formalisms are instantiated into mass/energy physicality using physicodynamically-inert configurable switch-settings. Representational Material Symbol Systems (MSS) are also used to prescribe logical functions instructed by Prescriptive Information (PI). Physical symbol vehicles (tokens) are sequenced according to rules, not laws. These rules are shared by source and destination governed only by arbitrary pre-agreements, not by laws or physical constraints. Most of life’s instructions are prescribed by coded programming which is often superimposed and multi-dimensional. This programming must be cybernetically processed by nanocomputers. Formal functional work, not just the work of physics, is done by ingenious molecular machines. Life exists in the form of Sustained Functional Systems (SFS) that continually compute interdependent, highly cooperative haltings. Integrated circuits orchestrate into physicality homeostatic metabolism. Active selections alone achieve sustained far from equilibrium defiance of 2nd Law thermodynamic propensities. Life is not a thermodynamic state. Life consists of prescribed computational processes.
INTEGRATION OF SPECIAL KNOWLEDGE INTO CRIMINAL PRO-CEEDINGS: PROCEDURAL APPROACHES AND SIGNIFICANCE FOR THE WORK OF INVESTIGATORS
Authors: Sarantseva Alena
Published: February 2025

The article is dedicated to the analysis of the application of special knowledge and forensic techniques in criminal proceedings. It examines the role of forensic expert studies, the interaction between investigators and specialists, and the independent use of special knowledge by investigators. An overview of the legal and regulatory framework governing the use of special knowledge is provided, highlighting the most pressing issues and potential opportunities for their implementation in practical activities
PENERAPAN PENDEKATAN PMRI BERBASIS KONTEKSTUAL TERHADAP KEMAMPUAN BERPIKIR KRITIS SISWA KELAS IV SD
Authors: Khaq Sinkha Arza , Hilyana F. Shoufika , Ermawati Diana
Published: February 2025

Penggunaan pendekatan pembelajaran Matematika yang tidak sesuai dan tidak menarik bagi siswa menyebabkan siswa kurang mampu menganalisis, merumuskan masalah, dan menyimpulkan informasi untuk menyelesaikan masalah. Akibatnya, kemampuan berpikir kritis siswa masih rendah. Tujuan dari penelitian ini adalah untuk mengetahui apakah kemampuan berpikir kritis siswa kelas IV di SD 1 Kaliwungu Kudus berbeda sebelum dan sesudah diadakannya pembelajaran Matematika dengan penerapan Pendekatan Matematika Realistik Indonesia (PMRI) pada materi piktogram dan diagram batang. Penelitian ini menggunakan pendekatan kuantitatif dengan metode Pre-Experimental dan desain One Group Pretest-Posttest. Penelitian diadakan di kelas IV SD 1 Kaliwungu tepatnya di Desa Kaliwungu, Kecamatan Kaliwungu, Kabupaten Kudus. Dalam penelitian ini, 24 siswa kelas IV digunakan sebagai sampel dengan menggunakan teknik sampling jenuh. Pengumpulan datanya menggunakan teknik tes, untuk mengukur kemampuan berpikir kritis siswa. Siswa diberi instrumen tes yang terdiri dari lima soal yang ditulis dalam bentuk uraian. Data dianalisis menggunakan uji N-Gain berbantuan SPSS 25. Hasil penelitian menunjukkan peningkatan yang cukup efektif dengan presentase nilai N-Gain sebesar 58% dalam kategori sedang.
PENERAPAN MODEL PEMBELAJARAN TERHADAP KEMAMPUAN LITERASI NUMERASI SISWA: SYSTEMATIC LITERATURE REVIEW
Authors: Sektiwulan Adelia , Novaliyosi Novaliyosi , Nindiasari Hepsi
Published: February 2025

Keterampilan literasi numerasi dibutuhkan dalam berbagai aspek kehidupan, baik di rumah, pekerjaan, atau masyarakat. Pentingnya literasi numerasi tidak sejalan dengan kenyataan yaitu masih rendahnya kemampuan literasi numerasi siswa yang bisa dilihat dari hasil PISA tahun 2022. Berbagai faktor mempengaruhi kemampuan literasi numerasi siswa, salah satunya yaitu penerapan model pembelajaran di sekolah. Systematic literature review (SLR) dilakukan berdasarkan 18 artikel dari jurnal nasional terakreditas dalam bidang pendidikan matematika. Penelitian ini berfokus pada dua aspek, yaitu 1) model pembelajaran yang memengaruhi kemampuan literasi numerasi, dan 2) penerapan model pembelajaran pada setiap jenjang yang memengaruhi kemampuan literasi numerasi. Berdasarkan artikel yang di review ditemukan 11 model pembelajaran pada jenjang SD, SMP, dan SMA. Penerapan model pembelajaran pada SD yaitu PBL, STEAM, student facilitator explaining, mind mapping, dan RME. Pada SMP yaitu model pembelajaran PBL, inkuiri, RME, TGT, PLTL, CIRC, PjBL, TTW, dan CTL, sedangkan SMA penerapan model pembelajaran peer led team learning dan pembelajaran berbasis masalah. Hasil dari penelitian ini dapat memberikan ringkasan literatur dalam mengidentifikasi model pembelajaran untuk meningkatkan kemampuan literasi numerasi siswa.
ANALISIS KESIAPAN GURU MATEMATIKA DALAM MENGADOPSI KURIKULUM MERDEKA DI SEKOLAH MENENGAH ATAS KOTA GUNUNGSITOLI
Authors: Telaumbanua Ovitarni , Telaumbanua Yakin Niat , Zega Yulisman , Mendrofa Ratna Natalia
Published: February 2025

Kurikulum Merdeka merupakan inovasi pendidikan yang diinisiasi oleh pemerintah Indonesia untuk meningkatkan kualitas pendidikan. Implementasi kurikulum ini diharapkan dapat memberikan kebebasan kepada guru dalam merancang dan melaksanakan pembelajaran yang lebih kreatif dan inovatif. Latar belakang penelitian ini yakni penerapan Kurikulum Merdeka di SMA di Kota Gunungsitoli yang sudah mulai diterapkan pada tahun ajaran 2022/2023 khusus kelas X dan tahun ajaran 2023/2024 untuk kelas XI. Guru dalam hal ini meski sudah mengadopsi Kurikulum Merdeka namun sistem pembelajaran masih membutuhkan penyesuaian agar dapat menjalankan kegiatan pembelajaran dengan baik. Penelitian ini bertujuan untuk menganalisis kesiapan guru matematika di Sekolah Menengah Atas (SMA) di Kota Gunungsitoli dalam mengadopsi Kurikulum Merdeka. Metode penelitian yang digunakan adalah Kualitatif Deskriptif, dengan menggunakan angket dan wawancara sebagai teknik pengumpulan data. Sampel penelitian terdiri dari guru matematika di 5 SMA di Kota Gunungsitoli yang telah mengadopsi Kurikulum Merdeka dengan jumlah informan 11 orang guru matematika, 5 orang kepala sekolah 1 orang wakil kepala sekolah. Hasil menunjukkan bahwa kesiapan guru matematika dalam mengadopsi Kurikulum Merdeka yaitu 86,18% berada pada rentang 76%-90% dengan kategori siap. Untuk meningkatkan kesiapan guru matematika dalam mengadopsi Kurikulum Merdeka, diperlukan upaya yang terkoordinasi dan pelatihan yang berkelanjutan.
PENERAPAN PROBLEM BASED LEARNING UNTUK MENINGKATKAN KEMAMPUAN KOMUNIKASI MATEMATIS PESERTA DIDIK FASE D PADA KONTEN STATISTIKA
Authors: Syafira Hadaya , Sakur Sakur , Armis Armis , Anum Azline Widuas
Published: February 2025

Penelitian ini bertujuan untuk meningkatkan Kemampuan Komunikasi Matematis (KKM) peserta didik fase D di SMPN 4 Tambang dengan menerapkan Problem Based Learning (PBL) pada materi statistika. Penelitian ini menggunakan Penelitian Tindakan Kelas (PTK) yang melibatkan seluruh peserta didik kelas VIII yang meliputi 32 peserta didik kelas VIII_3 SMPN 4 Tambang. Penelitian dilakukan sebanyak empat pertemuan dan dilakukan pada semester genap tahun 2023/2024. Instrumen penelitian terdiri dari instrumen pengumpul data yang meliputi lembar pengamatan dan tes KKM. Teknik pengumpul data yang digunakan pada penelitian ini adalah teknik pengamatan dan teknik tes KKM. Data diperoleh melalui tes KKM dan observasi aktivitas peserta didik selama proses pembelajaran. Hasil penelitian menunjukkan bahwa penerapan PBL dapat memperbaiki proses pembelajaran dan KKM peserta didik SMPN 4 Tambang dibandingkan dengan model pembelajaran konvensional. Peningkatan KKM peserta didik dilihat dari hasil analisis KKM secara klasikal. Selain itu, penerapan PBL juga memfasilitasi peserta didik untuk lebih aktif berdiskusi, bertukar pendapat, serta mampu untuk mengungkapkan ide dan solusi matematis secara jelas dan sistematis. Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa penerapan PBL dapat meningkatkan proses pembelajaran dan meningkatkan KKM peserta didik SMPN 4 Tambang tahun pelajaran 2023/2024 pada konten statistika.
EFICAZ PROTECCIÒN DE LOS DERECHOS POLITICOS ELECTORALES DE LOS PUEBLOS INDIGENAS EN MÈXICO
Authors: Graciela Cervantes Bravo Irina
Published: February 2025

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CONSTITUCIONALISMO E SOLIDARIEDADE NA PANDEMIA DE COVID-19
Authors: Zanotta Calçada Luís Antonio , Rodrigues Reck Janriê
Published: February 2025

O presente artigo busca avaliar a posição da solidariedade no âmbito constitucional, analisando essa com relação à pandemia de COVID-19. A partir do constitucionalismo como construção histórica será apresentada a solidariedade inserida nas cartas constitucionais, tanto como direito ou como princípio. Então se fará a análise da presença da solidariedade com relação ao direito fundamental da saúde, especificamente no cenário brasileiro, com verificação de casos práticos ocorridos no decorrer da pandemia de COVID-19, para constatar se apesar dos ditames constitucionais essa está presente ou não. Tal análise será realizada a partir da revisão bibliográfica documental, jurisprudencial e normativa, nacional e estrangeira.
Implementasi Hak Pendidikan Anak Pada Lembaga Pembinaan Khusus Anak Kantor Wilayah II Jakarta
Authors: Anwar Sadat Tyastiti Chandrawati , Permatasari Pita
Published: February 2025

The importance of protecting children’s right is a legal obligation for Indonesia. One of The national goal of Indonesia that contained in prambule of constitution is to educate the life of the nation, either way through protecting the right to education for fostered children. The urgency of this research is to see the implementation of the children who must be protected in Indonesia. The formulation of the problems in this research are : 1) How is the implementation of the right to education of children at LPKA Regional Office II Jakarta? 2) what are the obstacles to the implementation of the right to education of children at LPKA Regional Office II Jakarta?. This research is empirical legal research using primary and secondary data. The approach in this research are statutory research and conseptual approach. The results of the research showed that the implementation has been done even thougt it was not fully in accordance with the regulation (The decision of Minister of Law and Human Rights about Guidelines for the treatment of children in Bapas, LPAS, dan LPKA 2014). The obstancles to the implementation of the right to education of children at LPKA Regional Office II Jakarta are infrastructures consisting of inadequate classrooms, sufficient stationery, and teachers who not apply pedagogical competencies.
Problematik Akta Perdamaian Pada Penyelesaian Sengketa Keperdataan Melalui Mediasi
Authors: Sulistianingsih Dewi , Fibriani Indira
Published: February 2025

The purpose of this paper is to describe and analyze the settlement of civil disputes through mediation. Mediation is a dispute resolution process that is faster and cheaper, and provides access to the parties to resolve disputes. This paper is based on research conducted using library research. the approach used is a conceptual approach. The results in mediation are decisions that are expected to satisfy the parties so that in the future it can be carried out properly by the disputing parties. The dispute resolution process through mediation is assisted by a mediator. The mediation peace deed is made as a sign of the end of the dispute and the disputing parties have agreed to make peace and are binding on the disputing parties. The legal force between the results of mediation in court and the settlement of civil disputes through mediation is the same, namely permanent legal force. The legal consequences if the parties or one of the parties do not want to carry out the mediation peace deed, the trial can be continued. Settlement of disputes by means of Mediation in dispute resolution outside the court can produce efficient decisions, fast resolutions, the resulting decisions are satisfactory, and aim to resolve conflicts between the parties
Konsep Maladministrasi Sebagai Pembaruan Model Pengungkapan Tindak Pidana Korupsi
Authors: Faisal Muhammad , Rifai Andi Tenri Famauri
Published: February 2025

This study aims to analyze the phenomenon of acts of corruption that have undergone changes in terms of form. The urgency of this research is to formulate several methods that can be more effective in following the development of acts of corruption that occur. This research is a normative legal research with a concept and statutory approach. The results of the study indicate that the model for disclosing criminal acts of corruption must be updated by looking at other aspects or forms of examination to open up initial loopholes in the disclosure of criminal acts of corruption. Maladministration examinations, which are currently still relatively new to be implemented, can be used as a model for disclosing criminal acts of corruption, especially those that ensnare state officials. A maladministration examination can reveal other hidden motives that influence a state official in fulfilling his administrative and legal obligations.
Kajian Kriminologi Terhadap Pengunaan Mata Uang Kripto Sebagai Media Pencucian Uang
Authors: Kurniawan Lendra Dika , Rahmawan Alfin Dwi , Manik Jeanne Darc Noviayanti
Published: February 2025

The purpose of this research is to see the loopholes for the perpetrators of money laundering through the Bitcoin Cryptocurrency media in carrying out their actions. This study uses a socio-legal research approach. Socio-legal is known as research that involves a social approach in studying legal studies or across disciplines. Sociolegal studies are an alternative approach that examines doctrinal studies of law. The results in this study are based on several case findings and also some literature, Bitcoin cryptocurrency provides opportunities for illegal transactions or transactions that are used for negative actions. There is strong speculation that Bitcoin is very vulnerable to be used as a medium for money laundering or other misuse such as terrorism financing, arms and drug trafficking to several other forms of crime. This is possible because Cryptocurrency has a Blockchain-based encryption system that has sufficient effectiveness, complexity, and anonymity. There are also attempts to engineer Bitcoin as a recognized currency in Indonesia, this can be seen from the use of Bitcoin and the emergence of legality against Bitcoin Cryptocurrency.
O O REGIME DE AJUSTAMENTO, ESPACIALIDADE E INTERTEXTUALIDADE EM TORTO ARADO
Authors: Abriata Vera Lucia Rodella , Ribeiro Santos Flavia Karla , Fernandes Camilla , Cosci Tania Regina Cosci
Published: February 2025

Esta pesquisa, que tem por base o instrumental teórico da semiótica discursiva e da Sociossemiótica, analisa o romance Torto Arado, de Itamar Vieira Júnior, com o objetivo de apreender   a relação intertextual entre a obra e a capa do romance em sua edição brasileira, ilustrada por Aline Bispo. Outro objetivo é observar como o regime de interação por ajustamento se manifesta na construção dos sentidos do romance. Interessa-nos ainda desvelar como se projeta a espacialidade na narrativa e a correlação entre categorias do plano da expressão e do plano de conteúdo dos textos, que comporta grades de leitura possíveis, ou seja, valores recobertos por arranjos figurativos dos mais abstratos aos mais icônicos.
A FORÇA PERFORMATIVA DO DISCURSO MÉDICO NO TRATAMENTO DE MULHERES NEGRAS
Authors: Santos Elaine De Moraes , Duarte Amanda Da Silva , Batista Júnior Ovídio Da Conceição Batista Júnior
Published: February 2025

Para a escrita deste artigo, selecionamos o caso de racismo cometido por uma ginecologista brasileira e divulgado jornalisticamente, no Brasil, em junho de 2023. Recortando a publicação das alegações da acusada no trecho da audiência publicado pelo Fantástico (2023) enquanto sequência dialógica (Rajagopalan, 2019) constituinte do corpus de análise, objetivamos analisar a força performativa da fala médica sobre a saúde de mulheres negras. Para tanto, filiamo-nos à perspectiva teórica da (Nova) Pragmática, sobretudo aos pressupostos de autorias como Rajagopalan (2019), Butler (2021) e Vallada e Pinto (2023). Por meio da análise, compreendemos que os atos ilocucionários (Austin, 1990), produzidos pelo dizer, pautam-se na defesa da médica das acusações de que houve racismo em seu atendimento. Para além disso, pelas falhas no ritual linguístico, nos trechos de depoimento divulgado, entendemos que a reprodução das afirmações da profissional classifica, em uma conduta racista, todas as pessoas negras como sujeitos que possuem um odor muito forte, o que aponta para a ambiguidade dos atos de fala mobilizados.
Palavras-chave: enunciados ofensivos; atos de fala; racismo; mulheres negras.
Overall Layoff Fairness Perception and Laid-off Workers’ Turnback Intention
Authors:   Korean Academy Of Management, Le Nguyen Uyen Thao Le Nguyen Uyen Thao , Lee Sang-Min , Lee Min Kyoung
Published: February 2025

The large-scale layoffs following COVID-19 have shifted organizations' perspectives
on laid-off employees. To facilitate post-recession recovery and
growth, companies are increasingly considering boomerang hiring. However,
research on the determinants of laid-off workers’ attitudes and post employment
behaviors is still lacking. This study aims to examine the impact of overall
layoff fairness perception on turnback intention mediated by residual affective
commitment. Additionally, it explores whether company-led alumni outreach
activities and engagement in alumni outreach activities moderate this
relationship. The analysis of 230 Vietnamese laid-off workers indicated that
residual affective commitment mediates the relationship between overall layoff
fairness perception and turnback intention However, the moderating effects
and moderated mediating effects were not significant. The post-hoc analysis
showed that the mediating effects of residual affective commitment were
found in the analysis with moderator variables as independent variables. This
study contributes to the literature on layoff fairness by suggesting laid-off
workers’ attitudes, such as residual affective commitment, and behaviors, such
as turnback intention as subsequent factors of overall layoff fairness perception.
Furthermore, by distinguishing between company-led alumni outreach activities
and engagement in alumni outreach activities, it expands research on alumni
outreach activities by clarifying the effects of these two variables. Lastly,
it provides practical implications for organizations by suggesting that company-
led alumni outreach activities and engagement in alumni outreach activities
can enhance residual affective commitment and turnback intention.
The Effect of Data Gap on the Organizational Learning based on Data: Focusing on the Exploration and Exploitation Process
Authors:   Korean Academy Of Management, Ahn Hyerim
Published: February 2025

In the age of datafication, organizations have access to more information
than ever before and increasingly rely on data to make decisions. However,
few approaches analyze the impact of data gaps on organizational performance,
specifically focusing on the data gaps that may arise due to differences of
connectivity among organizations and individuals. In this study, I modeled
data gaps -instances where a dataset is missing a specific element or social
group- in two ways: (1) when an organization's ability to provide connectivity
is limited, resulting in missing data needed to measure the intended outcome
in terms of construct validity, and (2) when connectivity to specific members
is lost, leading to missing data from a portion of the target population in
terms of representativeness. March's (1991) model of organizational learning,
which emphasizes exploration and exploitation, was applied to analyze the
impact of these two types of data gaps on organizational knowledge and
the average knowledge of members, both of which are outcomes from the
organizational perspective, as well as on similarity, an outcome from the
individual perspective. The results showed that both types of data gaps restricted
exploration and reduced learning performance from the organizational perspective,
with the construct validity data gap having a particularly strong
impact. On the other hand, representativeness data gaps created a similarity
gap between those included in the organization's dataset and those excluded
from it during learning.
Assessment of the effectiveness of West Nile virus screening by analysing suspected positive donations among blood donors, Germany, 2020 to 2023
Authors: Orru' Stefano , Reissinger Annette , Filomena Angela , Heitmann Anna , Funk Markus Benedikt , Schmidt-Chanasit Jonas , Kreß Julia , Scheiblauer Heinrich , Cadar Dániel , Fiedler Sarah Anna
Published: February 2025

Background

The first autochthonous human West Nile virus (WNV)-positive cases in Germany were confirmed in 2019. Risk minimisation measures (RMM) were introduced in 2020; no WNV transfusion-transmitted infections have been reported to date.

Aim

To analyse German suspected WNV-positive blood donations during annual seasons 2020–23 to review donor testing requirements.

Methods

WNV look-back procedures were initiated as per German regulations and additional donor data were collected. Blood samples were analysed by metagenomic next-generation sequencing (mNGS), individual donor nucleic acid amplification technique (ID-NAT)-based testing and antibody (Ab) testing.

Results

Seventy-four cases were followed up after WNV-positive donor mini-pool screening. Forty-five (83%) of 54 samples tested with the cobas WNV assay and 14 (29%) of 49 samples tested with the RealStar WNV assay showed a reactive ID-NAT-based result; the viral load ranged between 70,251 IU/mL and values below quantification limits. Fifteen (23%) of 64 samples serologically tested were reactive with at least one of the three Ab tests performed; the previous WNV-negative donation was nearly always documented > 28 days before. Of 73 samples sequenced, mNGS detected WNV in 26 (36%) and other flaviviruses in 14 (19%) cases.

Conclusion

In some suspected cases where a WNV infection was not confirmed, mNGS demonstrated a cross-reaction with other flaviviruses. Ab testing could only detect WNV in late stages of infection. A NAT-based WNV donor screening with a detection limit of at least 120 IU/mL seems to be a sufficiently effective RMM at present. However, a continuous re-evaluation of test strategy is always required.
Innovation Analysis of Government Shopping Integration Platform through Digipay: Empowering MSMEs and Being Proud of Indonesian Products in the New Public Governance perspective
Authors: Tawaris Riet , Wardiyanto Bintoro
Published: February 2025

This study analyzes the implementation of the DigiPay platform for MSME Empowerment and Proud of Indonesian Products from the perspective of New Public Governance (NPG), with Diffusion of Innovations Theory as the incorporated theory. The goal of DigiPay is to increase efficiency, transparency, and inclusion in government procurement of goods and services. The results show that DigiPay successfully integrates various stakeholders, including the government, the banking sector, and small and medium enterprises (MSMEs), in a digital ecosystem. This digital ecosystem supports MSME empowerment and local product marketing, and DigiPay also accelerates the procurement administration process. However, infrastructure and technological literacy still hinder the adoption of DigiPay. This research suggests improving ease of use and involving more people in adoption by using the Diffusion of Innovations Theory. To support sustainable and inclusive digital transformation, this research suggests that future researchers should strengthen cross-sector collaboration and digital education. This will also strengthen the MSME sector as part of the national economy.