bluuebunny/crossref_metadata_2025 huggingface dataset:
Interobserver Agreement among Cytopathologists in False-Negative Cases by Cytological Diagnosis with Endoscopic Ultrasound-Guided Fine Needle Aspiration in Solid Pancreatic Lesions
Authors: Shi Chen , Li Suwen , Chen Lihong , Hong Jianglong , Bao Junjun , Xu Zhangwei , Xu Jianming , Mei Qiao
Published: December 2022

Introduction: Early detection and accurate pathological assessment are critical to improving prognosis of pancreatic cancer. EUS has been widely used in diagnosing pancreatic lesions and can obtain histological diagnosis by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). However, comprehensive assessment of the interobserver agreement (IOA) among cytopathologists evaluating EUS-FNA specimens is still limited. Therefore, this study evaluated IOA among cytopathologists for EUS-FNA specimens of solid pancreatic lesions, especially in false-negative cases of cytological diagnosis and analyzed the factors that influence cytological diagnosis of EUS-FNA so as to improve the diagnostic efficiency of EUS-FNA. Methods: We retrieved EUS-FNA samples of pancreatic solid lesions from 2017 to 2021 and collected their clinical/cytological data. Two cytopathologists independently reviewed these cases using a quoted, novel standardized cytology scoring tool. Ultimately, we calculated IOA among cytopathologists and performed a binary logistic regression analysis to evaluate factors influencing the cytological diagnosis of EUS-FNA. Results: 161 patients were included, and 60 cases with a clinical diagnosis of pancreatic cancer but a cytological diagnosis of benign and atypical constituted the false-negative group. IOAs for cytological diagnosis of overall patients and the false-negative group were in perfect/moderate agreement with Kendall’s W values of 0.896 and 0.462, respectively. The number of diagnostic cells in the scoring tool had the highest level of agreement (κ = 0.721) for overall patients. There was at best moderate agreement on other quantity and quality parameters for both all cases and false-negative group. Logistic regression analysis showed the number of diagnostic cells (OR = 6.110, p < 0.05) and amount of blood (OR = 0.320, p < 0.05) could influence cytological diagnosis. Conclusions: The false-negative rate of our study as high as 37.26% (60/161) is mainly related to strict standards of cytopathologists, and their ability to standardize pancreatic cytology is still improving. Suboptimal agreement among cytopathologists for cytological diagnosis and the number of diagnostic cells may be associated with the occurrence of false-negative diagnosis. Further regression analysis confirmed that the number of diagnostic cells and obscuring blood were important factors in cytological diagnosis. Therefore, refinement of cytological diagnostic criteria, standardization of specimen quality evaluation, and training of cytopathologists may improve the agreement of cytopathologists, thus improving the repeatability of cytological diagnosis and reducing the occurrence of false-negative events.
Current Standards and Future Outlooks in Metastatic Her2-Positive Breast Cancer
Authors: Suppan Christoph , Balic Marija
Published: December 2022

Background: Approximately 20% of all breast cancer cases show overexpression or amplification of the human epidermal growth factor receptor 2 (Her2) [Cancer Epidemiol Biomarkers Prev. 2017;26(4):632–41]. With the introduction of trastuzumab, lapatinib, and pertuzumab to the realm of treatment, a new era of antibody-drug conjugates had only begun. Within the last two decades, survival for patients with this tumor subtype has fundamentally improved. Summary: Beginning with a taxane plus trastuzumab/pertuzumab followed by trastuzumab deruxtecan, the first- and second-line treatments are set in stone. With the introduction of tucatinib as a newer tyrosine kinase inhibitor in combination with capecitabine and trastuzumab, there is one efficient line of treatment available after trastuzumab deruxtecan or even earlier in selected cases with active brain metastasis. Especially for later stages of disease, several combination strategies are under investigation. There is still a lack of positive results on immune checkpoint inhibition combined with Her2-targeted therapy, but hopefully an extension to the treatment algorithm will be on its way soon. Key Messages: With the HER2CLIMB trial, patients with brain metastasis were no longer excluded from bigger trials, and international guidelines implemented its presence or absence in their decision trees [N Engl J Med. 2020;382(7):597–609]. Curing Her2-positive metastatic breast cancer, or at least living a long life with this disease, is increasingly becoming a reality.
Cross-Sectional Observational Study of Typical in utero Fetal Movements Using Machine Learning
Authors: Vasung Lana , Xu Junshen , Abaci-Turk Esra , Zhou Cindy , Holland Elizabeth , Barth William H. , Barnewolt Carol , Connolly Susan , Estroff Judy , Golland Polina , Feldman Henry A. , Adalsteinsson Elfar , Grant P. Ellen
Published: December 2022

Early variations of fetal movements are the hallmark of a healthy developing central nervous system. However, there are no automatic methods to quantify the complex 3D motion of the developing fetus in utero. The aim of this prospective study was to use machine learning (ML) on in utero MRI to perform quantitative kinematic analysis of fetal limb movement, assessing the impact of maternal, placental, and fetal factors. In this cross-sectional, observational study, we used 76 sets of fetal (24–40 gestational weeks [GW]) blood oxygenation level-dependent (BOLD) MRI scans of 52 women (18–45 years old) during typical pregnancies. Pregnant women were scanned for 5–10 min while breathing room air (21% O2) and for 5–10 min while breathing 100% FiO2 in supine and/or lateral position. BOLD acquisition time was 20 min in total with effective temporal resolution approximately 3 s. To quantify upper and lower limb kinematics, we used a 3D convolutional neural network previously trained to track fetal key points (wrists, elbows, shoulders, ankles, knees, hips) on similar BOLD time series. Tracking was visually assessed, errors were manually corrected, and the absolute movement time (AMT) for each joint was calculated. To identify variables that had a significant association with AMT, we constructed a mixed-model ANOVA with interaction terms. Fetuses showed significantly longer duration of limb movements during maternal hyperoxia. We also found a significant centrifugal increase of AMT across limbs and significantly longer AMT of upper extremities <31 GW and longer AMT of lower extremities >35 GW. In conclusion, using ML we successfully quantified complex 3D fetal limb motion in utero and across gestation, showing maternal factors (hyperoxia) and fetal factors (gestational age, joint) that impact movement. Quantification of fetal motion on MRI is a potential new biomarker of fetal health and neuromuscular development.
Multiparametric Strategy to Predict Early Disease Decompensation in Asymptomatic Severe Aortic Regurgitation
Authors: Kočková Radka , Línková Hana , Hlubocká Zuzana , Mědílek Karel , Tuna Martin , Vojáček Jan , Skalský Ivo , Černý Štěpán , Malý Jiří , Hlubocký Jaroslav , Mizukami Takuya , De Colle Cristina , Pěnička Martin
Published: December 2022

Background:

Use of the current echocardiography-based indications for aortic regurgitation (AR) surgery might result in late valve replacement at the stage of irreversible myocardial damage. Therefore, we aimed to identify simple models combining multiple echocardiography or magnetic resonance imaging (MRI)–derived indices and natriuretic peptides (BNP [brain natriuretic peptide] or NT-proBNP [N-terminnal pro-B type natriuretic peptide]) to predict early disease decompensation in asymptomatic severe AR.

Methods:

This prospective and multicenter study included asymptomatic patients with severe AR, preserved left ventricular ejection fraction (>50%), and sinus rhythm. The echocardiography and MRI images were analyzed centrally in the CoreLab. The study end point was the onset of indication for aortic valve surgery as per current guidelines.

Results:

The derivative cohort consisted of 127 asymptomatic patients (age 45±14 years, 84% males) with 41 (32%) end points during a median follow-up of 1375 (interquartile range, 1041–1783) days. In multivariable Cox regression analysis, age, BNP, 3-dimensional vena contracta area, MRI left ventricular end-diastolic volume index, regurgitant volume, and a fraction were identified as independent predictors of end point (all
P
<0.05). However, a combined model including one parameter of AR assessment (MRI regurgitant volume or regurgitant fraction or 3-dimensional vena contracta area), 1 parameter of left ventricular remodeling (MRI left ventricular end-diastolic volume index or echocardiography 2-dimensional global longitudinal strain or E wave), and BNP showed significantly higher predictive accuracy (area under the curve, 0.74–0.81) than any parameter alone (area under the curve, 0.61–0.72). These findings were confirmed in the validation cohort (n=100 patients, 38 end points).

Conclusions:

In asymptomatic severe AR, multimodality and multiparametric model combining 2 imaging indices with natriuretic peptides, showed high accuracy to identify early disease decompensation. Further prospective studies are warranted to explore the clinical benefit of implementing these models to guide patient management.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02910349
Coronary Wave Intensity Analysis as an Invasive and Vessel-Specific Index of Myocardial Viability
Authors: Ryan Matthew , De Silva Kalpa , Morgan Holly , O’Gallagher Kevin , Demir Ozan M. , Rahman Haseeb , Ellis Howard , Dancy Luke , Sado Daniel , Strange Julian , Melikian Narbeh , Marber Michael , Shah Ajay M. , Chiribiri Amedeo , Perera Divaka
Published: December 2022

Background:

Coronary angiography and viability testing are the cornerstones of diagnosing and managing ischemic cardiomyopathy. At present, no single test serves both needs. Coronary wave intensity analysis interrogates both contractility and microvascular physiology of the subtended myocardium and therefore has the potential to fulfil the goal of completely assessing coronary physiology and myocardial viability in a single procedure. We hypothesized that coronary wave intensity analysis measured during coronary angiography would predict viability with a similar accuracy to late-gadolinium–enhanced cardiac magnetic resonance imaging.

Methods:

Patients with a left ventricular ejection fraction ≤40% and extensive coronary disease were enrolled. Coronary wave intensity analysis was assessed during cardiac catheterization at rest, during adenosine-induced hyperemia, and during low-dose dobutamine stress using a dual pressure-Doppler sensing coronary guidewire. Scar burden was assessed with cardiac magnetic resonance imaging. Regional left ventricular function was assessed at baseline and 6-month follow-up after optimization of medical-therapy±revascularization, using transthoracic echocardiography. The primary outcome was myocardial viability, determined by the retrospective observation of functional recovery.

Results:

Forty participants underwent baseline physiology, cardiac magnetic resonance imaging, and echocardiography, and 30 had echocardiography at 6 months; 21/42 territories were viable on follow-up echocardiography. Resting backward compression wave energy was significantly greater in viable than in nonviable territories (−5240±3772 versus −1873±1605 W m
−2
s
−1
,
P
<0.001), and had comparable accuracy to cardiac magnetic resonance imaging for predicting viability (area under the curve 0.812 versus 0.757,
P
=0.649); a threshold of −2500 W m
−2
s
−1
had 86% sensitivity and 76% specificity.

Conclusions:

Backward compression wave energy has accuracy similar to that of late-gadolinium–enhanced cardiac magnetic resonance imaging in the prediction of viability. Coronary wave intensity analysis has the potential to streamline the management of ischemic cardiomyopathy, in a manner analogous to the effect of fractional flow reserve on the management of stable angina.
Kalyptoidy: the nomenclatural status of new zoological nomina originally published as synonyms, with examples in herpetology and comments on taxonominal databases
Authors: DUBOIS ALAIN
Published: December 2022

The Rules provided by the Code for the nomenclatural status of nomina originally published as invalid synonyms of nomina considered valid are complex, and often ignored or misunderstood by taxonomists. A detailed analysis of these Rules is presented and a terminology is proposed for the categories of nomina. The actual implementation of these Rules is studied in 121 examples in amphibians and reptiles and in two herpetological databases, and warnings are given concerning the reliability of the latter. A few changes are recommended in the wording of Article 11.6.1 of the Code.
The authorship and date of the familial nomen Dermochelyidae (Chelonii)
Authors: FRÉTEY THIERRY
Published: December 2022

The nomen of the family Dermochelyidae, with currently a single extant species, Dermochelys coriacea (Vandellius, 1761), has been attributed to different authors. This situation led us to research the sources and information about the various nomina (families, genera and species) concerned in order to review their status, in compliance of the Code, and to solve the problem. The logonymic lists concerning Dermochelyidae, Dermochelys and Dermochelys coriacea are reviewed, corrected and completed. The family nomen must be written as Dermochelyidae Baur, 1888.
Reflections on Pavlinov (2021): understanding and expanding the study of the history and philosophy of nomenclature, a comprehensive state of the art
Authors: SALIBA ELIE MARIO
Published: December 2022

The philosophy of nomenclature (onymology/taxonymy) is an underdeveloped discipline. The book Taxonomic nomenclature of Pavlinov (2021) explores the history of scientific nomenclature and analyzes the theoretical and conceptual elements that underpin this discipline. It is a rich and comprehensive resource for both novice taxonomists, interested in the history and in nomenclature, and the more experienced, seeking to expand their knowledge of the field. In addition to the review, a deepening of the notions of taxonomic freedom and nomenclatural norms and principles, and a consensus on the binominal vs. binomial debate are proposed. The new concepts of methodology freedom and quality freedom are introduced, as well as some reflections on the notions of monosemy and universality.
The larvae of caddisfly species (Insecta, Trichoptera) in northern Thai streams and their relationships to environmental variables
Authors: SEETAPAN KRIENGKRAI , PROMMI TAENG ON
Published: December 2022

There have been few systematic studies on Trichoptera larvae in Thailand. The larval stages of the endemic species remain mostly unknown. Continued work on describing the larval stages of species will improve the precision of water quality monitoring metrics and enable ecological studies of species. This paper describes the unknown larvae of Hydropsyche pallipenne Banks 1938 and Hydropsyche askalaphos Malicky & Chantaramongkol 2000, with their identities deduced from the fact that both the larvae described here and identifiable adult specimens were sampled at the same location. Also, the effects of environmental variables on the distribution of caddisfly larvae in northern Thai streams were investigated. In total, 41 taxa from seven streams were identified, representing twenty-four genera and thirteen families. The Hydropsychidae were the most numerous family collected, accounting for 1,487 specimens (54%). Trichopteran abundance (for Triaenodes sp., Marilia sumatrana, Amphipsyche meridiana, Hydropsyche askalaphos, Leptocerus sp., Ganonema sp., Chimarra cf. akkaorum, Cheumatopsyche cf. dubitans, Macrostemum sp., and Leptocerus sp.) is influenced by environmental factors such as water temperature, dissolved oxygen, total dissolved solids, ammonia nitrogen, nitrate nitrogen, and pH. Because of their significant responses to environmental fluctuations, the caddisfly assemblage proved useful in identifying variations in water quality conditions in northern Thai streams.
Spatiotemporal Plasma-Particle Characterization of Dry Aerosols Using Nanosecond, Femtosecond, and Filament Laser-Produced Plasmas
Authors: Latty Kyle S. , Hartig Kyle C.
Published: December 2022

The ability to rapidly characterize dry aerosols in air using laser-induced breakdown spectroscopy (LIBS) with femtosecond laser pulses promises advancement towards real-time atmospheric sampling and standoff capabilities. Of particular interest is the ability to apply LIBS in the context of low-particle loaded environments where discrete particle interactions must be observed within the sampling volume of the laser-produced plasma (LPP). In this study, dry nanoparticles in suspension are generated from a standard solution and sampled in air using Q-switched nanosecond (ns-) pulses, short-focus (SF) femtosecond (fs-) pulses, and filaments. Short time-gated plasma images are captured to observe spatially and temporally varying discrete plasma-particle interactions, which is shown to influence early air breakdown behavior and subsequent plasma evolution. Along with images, photo-multiplier tube (PMT) measurements are conducted where strong spatiotemporal dependencies are exhibited by the collected emission signal on particle proximity and plasma expansion behavior. Finally, conditional analysis is performed on LIBS measurements to determine associated sampling probabilities and filter out spectra with poor or absent emission peaks with an adaptive threshold algorithm.
Return-to-Manual Performance can be Predicted Before Automation Fails
Authors: Griffiths Natalie , Bowden Vanessa , Wee Serena , Loft Shayne
Published: December 2022

Objective

This study aimed to examine operator state variables (workload, fatigue, and trust in automation) that may predict return-to-manual (RTM) performance when automation fails in simulated air traffic control.

Background

Prior research has largely focused on triggering adaptive automation based on reactive indicators of performance degradation or operator strain. A more direct and effective approach may be to proactively engage/disengage automation based on predicted operator RTM performance (conflict detection accuracy and response time), which requires analyses of within-person effects.

Method

Participants accepted and handed-off aircraft from their sector and were assisted by imperfect conflict detection/resolution automation. To avoid aircraft conflicts, participants were required to intervene when automation failed to detect a conflict. Participants periodically rated their workload, fatigue and trust in automation.

Results

For participants with the same or higher average trust than the sample average, an increase in their trust (relative to their own average) slowed their subsequent RTM response time. For participants with lower average fatigue than the sample average, an increase in their fatigue (relative to own average) improved their subsequent RTM response time. There was no effect of workload on RTM performance.

Conclusions

RTM performance degraded as trust in automation increased relative to participants’ own average, but only for individuals with average or high levels of trust.

Applications

Study outcomes indicate a potential for future adaptive automation systems to detect vulnerable operator states in order to predict subsequent RTM performance decrements.
Foreign Direct Investment, Institutional Quality and Sustainability: Cross-country Analysis Using Different Estimators
Authors: Krishnankutty Raveesh , M C Minimol , Tiwari Aviral Kumar
Published: December 2022

This article analyses the impact of institutional quality and sustainability on FDI. To achieve the objective, the study utilises data from 189 countries for 19 years, from 1996 to 2017. For estimation, the study uses several approaches such as pooled panel least squares with fixed and random effect models, generalised method of moments and panel quantile regression. The study finds that FDI and institutional quality steers the sustainability of the participating countries, primarily by creating and maintaining a conducive environment for investment and trade. We also confirmed that institutional quality variables can predict the FDI inflow across the countries. This is the first study in our knowledge that adopts different estimations and thereby ensures the robustness of the research findings. Moreover, our study is unique by including a new variable, i.e., the environmental performance index, to understand the sustainability aspects of FDI and the institutional quality.

JEL Codes: Q56, C33, G28, E02, E22, F21
Microstructural and thermal analysis of alumina modified carbon/phenolic composites after ablation testing
Authors: Ali Sanan , Ahmad Shehryar , Baluch Abrar H , Ramzan Muhammad , Saleem Mohsin , Bilal Muhammad , Naseem Kashif
Published: December 2022

Thermal and ablative performance of alumina-modified carbon phenolic composites has been experimentally investigated. Pristine, 2, 4, and 6wt.% alumina particles modified composites were fabricated by hand layup followed by vacuum bagging process. Linear ablation rate was determined by the oxyacetylene flame test whereas thermogravimetric analysis determined thermal stability. Furthermore, SEM and EDS were done on ablated samples for morphological and elemental analysis whereas to determine individual phases, XRD was done. It was found that the addition of alumina initially at 2wt.% enhanced the ablation resistance but with further increase in the concentration of alumina above 2wt.%, ablation resistance decreased. Thermogravimetric analysis found that char yield of alumina-modified composites increased with an increase in alumina concentration.
Career Identity Statuses Derived From the Career Identity Development Inventory: A Person-Centered Approach
Authors: Wendling Elodie , Sagas Michael
Published: December 2022

The Career Identity Development Inventory (CIDI) was designed to be used at the person level to assign individuals in a career identity status that would indicate how they approached a career identity crisis and identify developmental needs to resolve career identity concerns. However, given that CIDI has not been tested using a person-centered approach, the first aim of this study was to demonstrate whether and how CIDI can be used to determine individuals’ career identity statuses that are theoretically informed by Marcia’s identity status paradigm and neo-Eriksonian identity literature. Using a sample of 410 US college graduates, we identified, through a cluster analytic approach, eight groups of distinct career identity profiles, from which four groups resembled Marcia’s identity statuses and four other groups were unique variants of identity statuses that extended this paradigm and illustrated a more gradual process of career identity development. This person-centered approach enabled us to subsequently provide evidence of the criterion validity of CIDI, which was the second aim of this study. We examined how the eight career identity statuses derived from the cluster analysis differed according to validation-criterion variables and found that individuals assigned to statuses characterized by high levels of career identity commitments tended to have better career and psychosocial functioning than individuals assigned to statuses characterized by low levels of career identity commitments. Implications along with directions for future research are discussed with respect to developmental challenges associated with career exploration and critical processes of forming a constructed career identity.
Work values and hybrid careers in the gig economy: The evidence from an online labor market
Authors: Shevchuk Andrey , Strebkov Denis , Bögenhold Dieter
Published: December 2022

Current debates about the gig economy pay increasing attention to the heterogeneity of platform workers. Using a large sample of 10,574 freelancers from an international online labor market, this article investigates the association between individual work values and career trajectories, constructed as a combination of current employment status and future career intentions. The authors consider not only the pure form of freelancing but also hybrid models when people have multiple jobs, combining freelancing with a regular job as an employee (moonlighters) or starting their own business with hired employees (entrepreneurs). The findings suggest that freelancers, moonlighters, and entrepreneurs have distinct work value profiles reflecting the opportunities and constraints in gaining specific rewards from their work. In contrast to moonlighters, freelancers and entrepreneurs are similar in their relative preference for intrinsic values and ignoring security values. In contrast to freelancers, entrepreneurs and moonlighters value social recognition but do not seek a comfortable job. In contrast to entrepreneurs, freelancers and moonlighters prefer a job that meets their abilities. The authors argue that different work values must be better acknowledged when trying to reflect adequately on participation and mobility in the gig economy. The study contributes to a deeper understanding of the gig economy as well as to the general literature on the role of work values in labor markets.
Activin A alleviates neuronal injury through inhibiting cGAS-STING-mediated autophagy in mice with ischemic stroke
Authors: Liu Meilian , Li Yudie , Han Song , Wang Hongyu , Li Junfa
Published: December 2022

Activin A plays an essential role in ischemic stroke as a well-known neuroprotective factor. We previously reported that Activin A could promote white matter remyelination. However, the exact molecular mechanism of Activin A in neuronal protection post-stroke is still unclear. In this study, the middle cerebral artery occlusion/reperfusion (MCAO/R)-induced ischemic stroke mouse model and oxygen-glucose deprivation/reoxygenation (OGD/R)-treated primary neurons were used to explore the molecular mechanism of Activin A-mediated neuroprotection against ischemic injuries. We found that Activin A significantly inhibits cGAS-STING-mediated excessive autophagy through the PI3K-PKB pathway, but not mTOR-dependent autophagy. Consequently, Activin A protected neurons against OGD/R-induced ischemic injury and improved cell survival in a dose-dependent manner. In addition, Activin A improved neurological functions and reduced infarct size of mice with MCAO/R-induced ischemic stroke by inhibiting autophagy. Furthermore, Activin A depended on ACVR1C receptor to exert neuroprotective effects in 1 h MCAO/R treated mice. Our findings showed that Activin A alleviated neuronal ischemic injury through inhibiting cGAS-STING-mediated excessive autophagy in mice with ischemic stroke, which may suggest a potential therapeutic target for ischemic stroke.
Association of Cardiovascular Disease Risk Factors with Exclusive Smokeless Tobacco Use among US Males: Cross-Sectional Analysis of NHANES Data 2003-2018
Authors: Mushtaq Nasir , Sarwar Zoona , Kouplen Kate , Ahmed Rizwan , Beebe Laura A.
Published: December 2022

Purpose

To evaluate cardiovascular disease (CVD) risk factors among smokeless tobacco (ST) users. Exclusive ST users were compared to exclusive cigarette smokers and non-tobacco users.

Design

Cross-sectional study

Sample

Data were used from 16,336 adult males who participated in one of the National Health and Nutrition Examination Surveys (NHANES) from 2003 to 2018.

Measures

Biochemically verified tobacco use, CVD risk factors (hypertension, cholesterol levels, BMI categories), physical activity, cotinine concentration, and sociodemographic variables.

Analysis

Weighted analysis of the aggregate data was performed. ST users were compared with cigarette smokers and nontobacco users for their association with CVD risk factors. Associations were examined using univariate and multiple logistic regression with odds ratios (OR) and 95% confidence intervals (CI) reported.

Results

Prevalence of exclusive ST use was 4.4% whereas, exclusive smoking was 22.2%. Among ST users, 36.2% were hypertensive, 24.5% had high cholesterol levels, and most of them were overweight (31.1%) or obese (52.6%). ST users were more likely to have hypertension compared to smokers (aOR = 1.48, 95%CI: 1.12, 1.95) and nontobacco users (aOR = 1.41, 95%CI: 1.09, 1.83) adjusted for other covariates. ST users were twice more likely to be obese than nontobacco users (aOR = 2.18, 95%CI: 1.52, 3.11). ST users had significantly higher cotinine concentration than smokers.

Conclusion

Study findings indicate substantial association of ST use among males with hypertension and obesity which are independent risk factors of CVD.
Ezekiel’s Exagoge and the drama of intertextuality
Authors: Kramer Maxwell James
Published: December 2022

Ezekiel’s Exagoge is unusual as a Greek tragedy not only because it draws on Biblical rather than mythological subject matter but also because it makes such extensive use of an external source for much of its text: the Septuagint. Although the general concept of a Greek tragedy on a Jewish subject has drawn the attention of many scholars, the literary function of the Exagoge’s close relationship with the LXX text remains comparatively unexplored. In this article, I examine in detail several passages which connect the texts. These reveal that Ezekiel’s use of text from the Septuagint is not a symptom of a lack of poetic ingenuity but rather a deliberate literary choice. The intertextual links engage the audience intellectually by encouraging them to consider the ways in which Ezekiel receives, interprets, and occasionally departs from the Biblical text and its associated exegetical traditions. A comparison of Ezekiel’s poetry with that of the Greek poet Callimachus shows that Ezekiel’s engagement with scholarly, interpretational, and literary questions through the medium of poetry reflects the techniques and interests of the so-called Hellenistic poets, the sophisticated non-Jewish writers of his own age.
The ship of state: Metaphor and intertextuality in Philo of Alexandria
Authors: Hartog Pieter B.
Published: December 2022

This article discusses Philo’s use of the well-known state is ship metaphor. After offering a definition of topos and intertextuality, I discuss passages from the Philonic corpus in which this image features. I will argue that Philo’s use of the state is ship metaphor in most of his writings must be attributed to Philo’s familiarity with a literary trope rather than to intertextual borrowing. The exception is Philo’s Legatio ad Gaium where, I intend to show, Philo’s formulation of the metaphor draws an intertextual connection with Plato’s Republic.
Analytical trajectory prediction for skip re-entry of lifting vehicle
Authors: Zhao Penglei , Meng Jingwei , Chen Zhirun , Zhang Honghong , Yu Yubin
Published: December 2022

An analytical trajectory prediction method is put forward for skip re-entry of lifting vehicles. First, the 3-D analytical solutions of skip re-entry trajectory are developed, which are crucial to realize the analytical trajectory prediction. To facilitate the derivation, an auxiliary geocentric inertial frame is established to deal with the strong nonlinear problem caused by the Earth’s rotation. Thereafter, the analytical solutions of the downrange, crossrange, and velocity are approximated by the outer solutions of a two-time scale singular perturbation. The analytical solutions of the altitude and flight-path angle are developed using regular perturbation techniques which can decompose the strongly coupled and nonlinear system into a sequence of linear problems. Second, since the analytical solutions are with respect to the lift-to-drag ratio and bank angle, a method based on the EKF technique is proposed to estimate the lift-to-drag ratio and bank angle of the re-entry vehicle. Third, the analytical trajectory prediction schemes for the lifting re-entry vehicle with multiple bank reversals are put forward. The simulations show that the proposed analytical solutions are in good agreement with the numerical solutions, but the computation time of the analytical solutions is about two orders of magnitude less than that of the numerical solutions. In addition, the superior performance of the proposed analytical trajectory prediction method is well demonstrated by the simulation results.
Quantifying the excess carbon footprint and its main determinants of Spanish households
Authors: Mahía Ramón , de Arce Rafael
Published: December 2022

New evidence is provided on the determinants of the carbon footprint (CF) at the household level, using the Spanish case as an example and data from the Household Budget Survey (HBS) and the E-MRIO database. The research presents two new contributions. On the one hand, the basis of analysis on what we call ‘Excess per capita CF’, that is, the part of CF that exceeds a threshold associated with a minimum per capita consumption of each product in a household, below which level it is difficult to expect reductions in consumption. Second, the use of a quantile regression (QR) approach for the estimation of the drivers of CF. Both issues imply important changes in the consideration of the influence of some drivers considered so far in the literature, related to which CF quantile the household is in. These differences between an ordinary least squares (OLS) and the QR are especially significant for variables such as income, household size, occupation, age, household composition, housing area and area of residence.
Machine learning-based thermo-electrical performance improvement of nanofluid-cooled photovoltaic–thermal system
Authors: Diwania Sourav , Kumar Maneesh , Kumar Rajeev , Kumar Arun , Gupta Varun , Khetrapal Pavan
Published: December 2022

Hybrid photovoltaic–thermal (hPVT) collectors are devices that allow the conversion of sun energy into useful thermal and electrical energy simultaneously. The power obtained from the photovoltaic (PV) module introduces random fluctuations into the system. While obtaining the data for PV power output in advance and for reducing the impact of random fluctuations, exact day-ahead PV power prediction is crucial. Machine learning algorithms have been proven an effective tool in PV technology for day-ahead prediction of PV-power output. This research employs the Gaussian process regression method using the Matlab environment for forecasting the hPVT collector's performance operating with pure water and Fe/water nanofluid. A one-year historical data pertaining to solar irradiance as well as ambient temperature for Roorkee (29.8543 °N, 77.8880 °E), India location has been used to validate the proposed model. This data is utilized for day-ahead forecasting of solar irradiance and ambient temperature. The outcome elucidates that as the mass-flow rate increases, the thermo-electric performance of the hPVT collector enhances. Raising the mass-flow rate of Fe/water nanofluid from 0.01 to 0.1 kg/s, the cell temperature decreases by 9.35 °C and 9.47 °C, respectively, for the actual and predicted data. The thermal, electrical, as well as overall efficiency of the hPVT collector, improves by 2.73%, 7.11%, and 9.84%, respectively, using Fe/water nanofluid ( ϕ = 2%) in contrast to the water-cooled PVT system. Finally, results demonstrate that the outcomes obtained using the forecasted data closely follow the results obtained using the actual data. In conclusion, this analysis provides a comprehensive solution for utilizing nanofluids as a coolant in the most cost-effective ways.
Coalescing, Cross-Pollinating, Crystalising: Developing and Evaluating an Art Installation About Health Knowledge
Authors: Watfern Chloe , Triandafilidis Zoi , Vaughan Priya , Doran Barbara , Dadich Ann , Disher-Quill Kate , Maple Peter , Hickman Louise , Elliot Michele , Boydell Katherine M.
Published: December 2022

The HIVE is an arts-based knowledge translation (ABKT) project that showcases work undertaken across Maridulu Budyari Gumal: the Sydney Partnership for Health, Education, Research and Enterprise (SPHERE). Here, we present two distinct forms of data (reflective and evaluative) to tell the story of The HIVE and outline the project’s achievements and shortcomings. Reflective data are used to describe the process of establishing a creative, cross-disciplinary collaboration, in order to devise and produce The HIVE. Evaluative data are used to assess the impact of The HIVE on audiences. By presenting reflective and evaluative data together, we highlight that impact in ABKT cannot be reduced to an assessment of audience engagement with an ABKT end-product. Although audience impact is vital, in our experience, The HIVE also had a powerful impact on the researchers, health service users, artists and others who worked together to create it. The process of creating The HIVE informed research- and art-practice change, forged interdisciplinary networks, and enabled the growth of new patterns of knowledge sharing and collaboration. The reflective and evaluative data we present attest to different forms of impact resulting from the creation and exhibition of an ABKT project.
Threatened humanity in a tight world: Cultural tightness results in self-objectification
Authors: Wang Xijing , Chen Hao , Shi Jiaxin , Chen Zhansheng
Published: December 2022

Self-objectification can be considered as a specific kind of self-dehumanization that consists of a perception of oneself as more instrument-like than human-like and a decreased self-attribution of mental states. Self-objectification is commonly observed, and its contributing factors need to be better understood. In the present research, we examined whether cultural tightness, which entails strong social norms and punishments for deviant behaviors, is an antecedent to self-objectification. Our hypotheses were confirmed by four studies, involving quasi-experiments and fully controlled experiments ( N = 2,693). In particular, Chinese college students living in a region with a tight culture (compared to a loose culture, Study 1), American employees working in an industry with a tight corporate culture (compared to a loose culture, Study 2), American participants who were induced to support cultural tightness (vs. cultural looseness, Study 3), and those who were situated in a simulated tight culture (vs. a loose culture, Study 4) all showed increased levels of self-objectification. As such, they acknowledged their personhood less and focused more on their instrumentality. Implications are discussed.
Be my boss: Migrant youth and the contradiction of hope labour on Kuaishou
Authors: Zhou Min , Liu Shih-Diing
Published: December 2022

This article explores the platformisation of a popular short-video platform Kuaishou and its impact on Chinese migrant youth. Based on 4 years of field observations, this study examines how Kuaishou’s platformisation process has paradoxically empowered and constrained the agency of migrant youth through the construction of ‘hope labour’. This hope labour seeks to benefit from Kuaishou’s attention economy at the expense of growing uncertainty and precarity. In particular, with the intervention of the state and fierce market competition, Kuaishou’s operation is moving towards a Douyin model to attract more urban youth, resulting in less diversity and more uniformity. This article illustrates how the joint forces of the market and the state push the platforms towards increased homogeneity. It shows how Kuaishou configures a digital assembly line for migrant youth, reproducing the precarious hope that everyone can become his or her boss.
Comparative and parametric study of aluminium honeycomb sandwich composites and GRP
Authors: Rajput Arun , Mohammed Rabius Sunny , Sarkar Arunjyoti , Pradhan Rururaj
Published: December 2022

Sandwich composites are a special class of material because of distinctive properties such as lightweight, high damping and high energy absorbing capacity, which in turn make this material highly suitable for the shipbuilding industry. The traditionally used materials for hull construction in the shipbuilding industry are steel, Glass Reinforced Plastic (GRP) and wood which is prone to problems such as weight and strength reduction due to water absorption over a period of time. This manuscript presents a comparative study of specific energy absorption (SEA) of GRP sheets and two different aluminium honeycomb sandwich composites one of which has aluminium honeycomb core and aluminium face sheet/skin and the other has aluminium honeycomb core and GRP face sheet. Experiments are carried out on the GRP sheet and sandwich composite with aluminium honeycomb core and aluminium as face sheet using Charpy ASTM E-23 machine. The experimental results are compared with the numerical results obtained from Abaqus and are found to be in good agreement. Further, the numerical simulation has been carried out on sandwich composites and GRP sheets varying several parameters such as foil thickness of honeycomb in sandwich composites, and skin of sandwich composites (aluminium sheet and GRP). Failures have been discussed based on stress theories and the deformation patterns of sandwich composites and GRP sheets (obtained from the numerical and experimental investigation) have been compared. The maximum impulse force has also been presented by using the impulse-momentum equation. It has been found in the study that the aluminium honeycomb sandwich composites with aluminium as face sheet possess high energy absorption to mass ratio than the pure GRP sheets and the aluminium honeycomb sandwich composites with GRP sheet as skin. Further parametric study reveals that the energy absorption to mass ratio increases with increase in foil thickness in both type of honeycomb sandwich composites.
Graphene-integrated thermoplastic vulcanizates: Effects of in-situ vulcanization on structural, thermal, mechanical and electrical properties
Authors: Sarfraz Muhammad , Liaqat Waqas A , Ali Mohsin , Qaiser Asif A
Published: December 2022

Gaining considerable attention as valuable plastic static-dissipative materials, conductive polymer blends are used as supercapacitors, light emitting diodes, artificial muscles and biosensors. Thermoplastic vulcanizates (PECVs) were prepared by blending ethylene propylene diene monomer (EPDM) and polypropylene (PP) thermoplastic via in-situ compatibilization technique by using a suitable compatibilizer and curing system. Electrically conducting graphene filler was incorporated into the blend to impart electroconducting properties. Maintaining a constant PP/EPDM ratio of 80:20 for all specimens, PECVs containing different loadings of graphene filler were prepared through in-situ compatibilization method. Fourier-transform infrared spectroscopy analysis was performed to investigate chemical changes ensued as a result of compatibilization reactions. Addition of graphene into the blended PECVs slightly improved their processability and thermally stable as confirmed by tests performed on Differential Scanning Calorimetery and Thermogravimetric Analyser. Mechanical aspects of the blends, inspected by operating Universal Testing Machine and Rockwell Hardness Tester, were substantially improved on account of blend compatibilization and addition of graphene. Their electrical properties measured through four-probe technique revealed significant improvement in electrical conductivity of compatibilized PECVs due to incorporation of graphene filler.
A Qualitative Study of the Perspectives of Healthcare Professionals on Features of Digital Health Interventions to Support Physical Activity in Solid Organ Transplant Recipients
Authors: Handler Lauren , Jaloul Paula , Clancy Jessica , Cuypers Brittany , Muir Jayme , Hemphill Julia , Janaudis-Ferreira Tania , Gottesman Chaya , Wickerson Lisa , Lovas Mike , Cafazzo Joseph A. , Mathur Sunita
Published: December 2022

Introduction: Digital health interventions may support physical activity among solid organ transplant recipients. These interventions should be designed with users in mind, including healthcare professionals who counsel transplant recipients on physical activity to ensure acceptance and to promote an optimal user experience. The purpose of this study was to explore the perspectives of health care providers on the features of digital health interventions that would be useful in the promotion, implementation, and maintenance of physical activity among solid organ transplant recipients. Methods: This qualitative, cross-sectional study used semistructured interviews that were conducted remotely, via videoconferencing software, with providers who worked with transplant recipients. Interviews were transcribed, and an iterative-inductive, thematic analysis was used to identify common themes. Data were coded using NVivo software. Findings: Thirteen providers participated in this study. Four main themes were identified: (a) physical activity and exercise features (eg, physical activity guidelines, and exercise instructions); (b) credibility; (c) self-management; and (d) user engagement. Potential barriers to using digital health interventions included staffing requirements, professional regulatory issues, cost, perceived low patient motivation to use, and lack of technological literacy or access. Discussion: Digital health interventions were perceived to be a potential adjunct to current physical activity counseling practices, and part of an innovative strategy to address identified barriers to physical activity participation in solid organ transplant recipients.
Transforming U.S. Education to Prevent Youth Suicide
Authors: Mueller Anna S. , Abrutyn Seth , Diefendorf Sarah
Published: December 2022

Ready or not, American schools facing increasing rates of youth suicide must actively manage mental health crises and work to prevent suicide. Using insights from district-based fieldwork, we offer a sociological vision for building sustainable, equitable, and effective suicide prevention capacities across school communities.
Adult Children’s Influence on Parental Well-Being
Authors: Lee Kristen Schultz , Dennison Christopher R. , Barr Ashley B.
Published: December 2022

Population aging and widening disparities in healthy aging have increased attention to the social determinants of health and healthy aging. Unfortunately, our emphasis on the social determinants of health in adulthood has lacked the same intergenerational lens that is prominent in research focused earlier in the life course. Our research finds that having a college-educated adult child benefits parents’ health and well-being, particularly for disadvantaged parents. Although parental characteristics like education and family ties help to explain some of this effect, our and emerging work suggests that parents’ and children’s lives are inextricably linked, even after children have reached adulthood.