bluuebunny/crossref_metadata_2025 huggingface dataset:
Beeinflussen historische Meiler Gehäuseschnecken in bodensauren Buchenwäldern (Kermeter, Nationalpark Eifel)?
Authors: Kappes Heike
Published: June 2023

Die Platten der historischen Holzkohlemeiler weisen aufgrund der Ionenaustauscher-Funktion der Holzkohlereste eine veränderte Bodenchemie auf, u.a. sind dort pH-Wert und Kalziumverfügbarkeit erhöht. Es kann angenommen werden, dass dies einen Einfluss auf bodenlebende Arten mit kalziumreichem Exoskelett hat. Daher wurden exemplarisch Gehäuseschnecken aus 40 Laubstreuproben (à 300 cm2) von zehn paarweise beprobten Meilerresten und Kontrollflächen untersucht. Die Probennahmen erfolgten im Herbst 2006 in Laubwäldern des Kermeters. Hierbei wurden 491 Schnecken-Individuen aus 13 Arten nachgewiesen. Insgesamt waren Artenreichtum und Individuenzahlen aus Meilerflächen-Proben höher als von Freiflächen-Proben, aber die Unterschiede waren aufgrund der hohen Heterogeneität der Proben nicht signifikant. Die Ergebnisse weisen darauf hin, dass eine sehr kleinräumige Verbesserung der Bodenqualität weniger Einfluss auf Gehäuseschneckengesellschaften hat als andere Faktoren wie Habitatsstrukturierung und Mikroklima.
Gastropodenfauna im urban-industriellen Raum am Beispiel des westlichen Ruhrgebietes
Authors: Meßer Johannes
Published: June 2023

Zur Charakterisierung der Gastropodenfauna urban-industrieller Lebensräume wurden die urbanen Gehölze vor allem im Duisburger Norden, Industriebrachen, Parkanlagen und Gärten untersucht. Insgesamt wurden in den Gehölzen 37 Gastropodenarten und auf den Industriebrachen 34 Arten nachgewiesen. Mit Hilfe verschiedener statistischer Auswertungen werden die Gastropodengesellschaften analysiert und die Synanthropie der Arten eingeordnet. Es werden die Gastropoden-Zönosen des urban-industriell geprägten westlichen Ruhrgebietes beschrieben. Obwohl Städte als ungünstige Lebensräume für Mollusken gelten, ist die Artenvielfalt der untersuchten Standorte größer als in Untersuchungsflächen des Umlandes. Von entscheidender Bedeutung im urban-industriellen Raum sind die Ausbreitungsmöglichkeiten für Gastropoden durch Boden- bzw. Materialtransporte.
The molecular principles of chromosomal translocations
Authors:   , Streb Patrick
Published: June 2023

Chromosomal translocations (CTs) are a genetic hallmark of cancer. They could be identified as recurrent genetic aberrations in hemato-malignancies and solid tumors. More than 40% of all "cancer genes" were identified in recurrent CTs. Most of these CTs result in the production of oncofusion proteins of which many have been studied over the past decades. They influence signaling pathways and/or alter gene expression. However, a precise mechanism for how these CTs arise and occur in a nearly identical fashion in individuals remains to be elucidated. Here, we performed experiments that explain the onset of CTs: proximity of genes able to produce prematurely terminated transcripts, which leads to the production of transspliced fusion RNAs, and finally, the induction of DNA double-strand breaks which are subsequently repaired via EJ repair pathways. Under these conditions, balanced chromosomal translocations could be specifically induced.
Standardizing Life Cycle Organization: A Synergetic Quality Management Approach
Authors: Prokopovych I. V. , Kokhanov A. B. , Khamitov V. M. , Tikhenko V. M. , Dašić Predrag
Published: June 2023

Standardization is essential for innovation (on the impacts on design, manufacturing, and operation processes) and its dissemination, both within a country and internationally. A phenomenological information model has been developed for the system of standards, which will be used as an information base for integrated quality management systems, environmental safety, and energy saving depending on the type of products, requirements of technical regulations, and conformity assessment procedures. Phase portraits of the life cycle system of complex products were constructed, and a general expression for the Lyapunov exponents characterizing the overall behavior of the dynamic system in phase space was obtained. The presence of particular areas to which, regardless of the initial conditions, all phase trajectories rapidly evolve has been established. The critical conditions for the control parameters were found. A diagram was constructed that determines the stability of the system states of the life cycle of complex products. It was found that the processes of the life cycle of complex products are carried out in two stages: in the first, there is a rapid evolution of components and parameters of technical and software tools, as well as energetic elements of functional subsystems, which is reflected in a specific attractive section of phase portraits, in the second, further slow development along it.
Structuring of Modified Epoxy Composite Materials by Infrared Spectroscopy
Authors: Kashytskyi V. P. , Sadova O. L. , Melnychuk M. D. , Golodyuk G. I. , Klymovets O. B.
Published: June 2023

A comparative evaluation of the structuring processes of the epoxy polymer system with epoxy polymers modified with polyvinyl chloride solution and epoxy composites filled with finely dispersed titanium oxide powder was carried out. Analysis of the infrared (IR) absorption spectra of the studied epoxy polymer and epoxy composite materials showed the presence of deformation and valence vibrations of certain groups of atoms. The oscillations of groups of atoms with double bonds and regions of existence of triple bonds were also revealed. In the region of high frequencies, absorption bands correspond to valence vibrations of groups containing a hydrogen atom. The presence of triple bonds in the epoxy polymer system was determined, indicating unreacted functional groups. This fact corresponds to the low content of the gel fraction of unmodified epoxy polymers after heat treatment and indicates the formation of a system with insufficient chemical bonds. The absorption bands of the epoxy composite material filled with titanium oxide powder are characterized by a lower optical density and a larger peak area compared to the bands of the unmodified epoxy polymer, which indicates the formation of a higher number of crosslinking nodes of the epoxy composite material. The introduction of polyvinyl chloride into the composition of the epoxy polymer system increases the degree of structuring of epoxy polymers. However, a smaller number of formed chemical bonds of the modified epoxy polymer was recorded compared to epoxy composites containing titanium oxide particles. The highest degree of structuring is provided in polyvinyl chloride-modified epoxy composites containing titanium oxide powder due to intensive structuring and formation of double and triple bonds.
A Scheduling Model in Capturing Methane Gas from
Methane Clathrates Deposits
Authors: Anyanwu U. O. , Okafor O. C. , Nkwor C. A.
Published: June 2023

The execution of any project type, especially engineering-based projects, is usually time-based, efficiency-driven, and cost-effective. These factors are the deterministic parameters that engineer successful project completion. The application of scheduling models remains the best technique for achieving these three factors to their best degrees. Therefore, this study was centered on the impact study of applying the scheduling model in harvesting methane gas from methane clathrates deposits. Various data on gas hydrate reserves in the Niger Delta region of Nigeria were collected from relevant literature, studied, and analyzed. Such data includes the pictorial representation and description of the gas hydrate site in the Niger Delta region of Africa and various shapes and sizes of gas hydrate perimeters in the studied region positions of the gas reserves. The normal faults are projected on a bathymetric map of the study area and the bathymetric map of the Pockmark (with the stippled black line indicating the sea floor projection of a prominent N-S trending fracture in 3-D seismic data). As a type of scheduling model, the critical path method (CPM) was applied to develop the project’s work sequence using the activity on node (AON) architectural technique and Primavera P6 software after carefully identifying the primary operations involved in the project and their respective sub-operations or work breakdown structure (WBS). The risks associated with each operation were meticulously identified, with their consequent impact and exposure matrix determined using probabilistic measures of 1-5 according to the degree of the risk. Mitigation strategies were recommended for all the identified risks. The cost benefits of the project were X-rayed using parameters such as net present value (NPV), project payback time, internal rate of return (IRR), and net cumulative cash flow. From the results obtained, the CPM schedule showed that the project execution would last approximately ten months. All the operations involved in the project execution plan were all critical, proving that each activity should be completed within the scheduled run period. Else, the entire project would be affected. Also, risks with a high exposure matrix of 25, 12, and 4 were mitigated to 5, 3, and 0 using the recommended strategies. In addition, the project yielded an NPV of $20,736,951.04for the run period of 22 years after the execution of the project, IRR of 14%, and a payback time of 8 years (adding 2023 – the year of project execution) provided the daily production rate is maintained within 60,000-65,000MSCF/day. If the daily production rate increases, the cash flow and payback time will decrease. Therefore, the application of CPM in extracting methane gas from gas hydrates positively affected the operation through the vivid insights provided in workflow pattern/methodology risks effects and cost benefits.
Evaluation of Trunk Injection Techniques for Systemic Delivery of Huanglongbing Therapies in Citrus
Authors: Archer Leigh , Albrecht Ute
Published: June 2023

The bacterial pathogen associated with citrus huanglongbing (HLB) resides in the phloem of affected trees. The widespread abundance of the vector in Florida, the Asian citrus psyllid (Diaphorina citri), and the location of the pathogen in the tree vascular tissue limits the efficacy of foliar-applied therapies. Trunk injection is a crop protection strategy that applies therapeutic compounds directly into the tree vascular system, enabling their systemic distribution within the tree. However, limited information is available on the most effective methodology for implementing trunk injection at the commercial scale and the extent of damage inflicted by the injection. In this study, 5-year-old HLB-affected ‘Midsweet’ sweet orange (Citrus sinensis) trees were injected with the insecticide imidacloprid, the antibacterial oxytetracycline, or water. Injections occurred in Jun and Oct 2020 using three trunk injection techniques. Trees were monitored for external wounding and internal damage associated with injection, as well as tree health, bacterial titers, and yield for two production seasons. Low-pressure injection caused the least damage; however, it was less effective at delivering the tested compounds than medium- or high-pressure injection. Despite causing the greatest extent of external and internal damage at the injection site, injection of oxytetracycline significantly improved tree health, reduced bacterial titers, and increased yield in the two seasons of this study. Imidacloprid injection caused less wound damage but did not result in any lasting benefits to the trees. These results suggest that trunk injection of oxytetracycline could be an effective strategy for managing HLB and that the damage inflicted by this crop protection strategy can be reduced by selecting a suitable injection technique.
Revisiting the genesis of the adakite-like granitoids in collisional zones: Water-fluxed melting of intermediate to felsic rocks with dilution by low Sr/Y phases
Authors: Xie Yuan-Hui , Schwartz Joshua J. , Li Xiao-Wei , Cai Keda , Thomas Bader , Li Huan , Wang Fang-Yue , Zhang Xiao-Bing , Mo Xuan-Xue , Dong Guo-Chen
Published: June 2023

High-Sr/Y granitoids in continental settings are sometimes erroneously regarded as the products derived from partial melting of thickened/delaminated mafic lower curst under relatively higher pressures (>1.5 GPa) in a collisional orogenic setting. In fact, multiple magmatic processes in the trans-crustal magma system, such as recycling of antecrysts, crustal assimilation, and fractional crystallization, can create or modify the primary “adakitic” signature. As a result, the generation of adakitic magmas in continental settings remains controversial from a bulk-rock perspective. Here, we address the origin of adakitic plutonic rocks through geochemical and textural characterization of rock-forming minerals in the pyroxene-bearing Zhuyuan granodiorite, West Qinling, China. The Zhuyuan granodiorite formed in a post-collisional setting and primarily consists of resorbed orthopyroxene, three types of clinopyroxene, amphibole, two types of plagioclases, K-feldspar, biotite, and quartz. Type-1 Cpx has high XMg (70.0–81.7). Type-2 Cpx displays normal zoning and decreasing XMg (80.9 to 71.5) from the core to rim. Type-3 Cpx is reversely zoned, where the rims have higher XMg (75.5–86.9), Ni, Cr, suggesting a recharge event. Orthopyroxene has high-Ni and -Cr contents, as well as high XMg (80.9–82.8), indicative of antecrysts that grew in mafic magma reservoirs. The injection of magmas from different sources is supported by sieve-textured plagioclase and crystal size distributions of non-poikilitic amphibole. Finally, non-sieve textured plagioclase, biotite, K-feldspar, and quartz are late-crystallized phases, indicative of an orthocrystic origin. The melts in equilibrium with these orthocrysts display significantly higher Sr/Y values than the magma batches that crystallized other mafic phases (i.e., amphibole, clinopyroxene, and orthopyroxene). Thus, we propose that the system involved an initial high-Sr/Y melts in equilibrium with the orthocryst assemblage was generated by water-fluxed melting of intermediate to felsic sources. The addition of low Sr/Y non-orthocrysts (e.g., amphibole and pyroxene) and associated melt diluted the original “adakitic signal” in the magma reservoir and drove the bulk composition to more mafic values. Consequently, the Zhuyuan pyroxene-bearing granodiorite represents a mixture of crystals with diverse origins and distinct magma batches of various compositions (from felsic to mafic compositions). Our study emphasizes that the origin of adakitic granitoids cannot be clearly deciphered without geochemical analysis of the constituent minerals. We also suggest that Sr/Y values in plutons should be cautiously used in paleo-crustal thickness estimates in collisional settings because of possible open system scenarios as described here.
Mineralogy of the 1.45 Ga Wafangzi manganese deposit in North China: Implications for pulsed Mesoproterozoic oxygenation events
Authors: Yan Hao , Xu Lingang , Mao Jingwen , Tang Dongjie , Yang Xiuqing , Bai Yinzeng , Li Chao , Konhauser Kurt O. , Robbins Leslie J.
Published: June 2023

Ancient manganese (Mn) deposits are primarily characterized by the presence of Mn(II) carbonates that likely formed by the diagenetic reduction of precursor Mn(IV) oxides. As such, Precambrian sedimentary Mn deposits have been used as a line of evidence for the evolution of oxygen in Earth’s surface environments. However, recent studies have shown that these Mn(II)-carbonates have the ability to directly accumulate within anoxic water columns, where free oxygen does not play a role in their formation. This alternative pathway casts uncertainty on the robustness of using ancient Mn deposits to constrain the redox fabric of the past marine water columns. Here, we investigate the Wafangzi Mn and Fe ore deposit from the 1.45 billion-year-old Tieling Formation, North China. The deposit contains Mn(II, III) mineral phases (hausmannite, braunite) as inclusions, or unreacted residues, trapped within Mn(II) carbonate (Ca-rhodochrosite). Some nodules and oolites of Mn(II) and Fe(II)-carbonate phases are also present and display a banded structure with concentric rings. Mn(III) oxide (manganite) is present in a paragenetic assemblage along with hematite and replacement textures with braunite. The negative carbon isotope composition (δ13C, –7‰ to –4‰) from Mn(II) carbonate samples in the Wafangzi Mn deposit which are distinct from that of contemporaneous seawater (~0‰), along with petrographic and speciation analyses, collectively suggest that the Mn(II, III)- and Fe(II)-bearing mineral phases formed through the diagenetic reduction of primary Mn(IV)/Fe(III) minerals coupled to the oxidation of organic matter. Therefore, the Wafangzi Mn deposit suggests the presence of sufficiently oxygenated marine waters, overlying anoxic ferruginous deeper waters with a transitional manganous water layer that could have driven the redox cycling of Mn, Fe, and C. Given the contemporaneous economic Mn deposits in the 1.45 Ga Ullawarra Formation in Western Australia, our findings imply the existence of a transient, and perhaps widespread, pulsed oxygenation event in the mid-Proterozoic oceans.
Foliated-exotic duality in fractonic BF theories
Authors: Ohmori Kantaro , Shimamura Shutaro
Published: June 2023

There has been proposed two continuum descriptions of fracton systems: foliated quantum field theories (FQFTs) and exotic quantum field theories. Certain fracton systems are believed to admit descriptions by both, and hence a duality is expected between such a class of FQFTs and exotic QFTs. In this paper we study this duality in detail for concrete examples in 2+12+1 and 3+13+1 dimensions. In the examples, both sides of the continuum theories are of BFBF-type, and we find the explicit correspondences of gauge-invariant operators, gauge fields, parameters, and allowed singularities and discontinuities. This deepens the understanding of dualities in fractonic quantum field theories.
Low-energy excitations and transport functions of the one-dimensional Kondo insulator
Authors: Peters Robert , Rausch Roman
Published: June 2023

Using variational matrix product states, we analyze the finite temperature behavior of a half-filled periodic Anderson model in one dimension, a prototypical model of a Kondo insulator. We present an extensive analysis of single-particle Green’s functions, two-particle Green’s functions, and transport functions creating a broad picture of the low-temperature properties. We confirm the existence of energetically low-lying spin excitations in this model and study their energy-momentum dispersion and temperature dependence. We demonstrate that charge-charge correlations at the Fermi energy exhibit a different temperature dependence than spin-spin correlations. While energetically low-lying spin excitations emerge approximately at the Kondo temperature, which exponentially depends on the interaction strength, charge correlations vanish already at high temperatures. Furthermore, we analyze the charge and thermal conductivity at finite temperatures by calculating the time-dependent current-current correlation functions. While both charge and thermal conductivity can be fitted for all interaction strengths by gapped systems with a renormalized band gap, the gap in the system describing the thermal conductivity is generally smaller than the system describing the charge conductivity. Thus, two-particle correlations affect the charge and heat conductivities in a different way resulting in a temperature region where the charge conductivity of this one-dimensional Kondo insulator is already decreasing while the heat conductivity is still increasing.
CARE-SEEKING BEHAVIORS TOWARDS SEXUALLY TRANSMITTED INFECTIONS IN SAUDI ARABIA
Authors:   Family Medicine Senior Registrar., Abdullah Al Hajji MD SBFM Hanan , Ali Al Jamea MD SBFM Zahra ,   Family Medicine Consultant, SBFM, ABFM., Khalid Al Eid MD SBFM Fatoon ,   Family Medicine Consultant, SBFM, ABFM., Mohsen Al Hejji MD SBFM Fatmah ,   Family Medicine ConsultantMD, SBFM, ABFM, MHPE, MSchealth Administration., Al-Zaid Esra ,   Family Medicine Consultant, SBFM, ABFM., A. Al Bunaian Nada ,   Family Medicine Consultant, SBFM, ABFM.
Published: June 2023

Introduction: The concept of being infected with Sexually Transmitted Infections (STIs) is culturally sensitive in Saudi Arabia. Considering the impact and cost-effectiveness of early diagnosis and treatment, studying the care-seeking behaviors of the Saudi population towards STIs is essential. Therefore, this research aimed to evaluate care-seeking behaviors towards STIs and associated factors in Saudi Arabia. Methods: A cross-sectional study was conducted in 2022, including 420 adults aged 18-60, male and female, Native Arabicspeakers, and living in Saudi Arabia. A self-administered, community-based, and computerized questionnairewas constructed by the researchers and distributed via social media. Data analysis was managed using the Statistical Packagefor SocialSciences (SPSS) version 27. Results: A total of 420 participants were included in this study. 77% of respondents were willing to seek care once they suspect having STIs. All socioeconomic factors and perceived barriers were introduced into a logistic regression model that included different variables such as religion, workinghours, income, fear of legal issues, condom protection knowledge, STIs symptomsknowledge,and transmission routesknowledge had significant relationship with willingness to seek healthcare.Furthermore,more than 52% had no obstaclesto report STIs, while the remaining respondents had some obstacles. The three most prominent obstacles werefear of breaching confidentiality (~30%), fear of stigma (~21%), and fear of partnerresponse (~20%). Conclusions: The study showed good-seeking behavior as the majority of the respondents were willing to seek healthcare. However, several factors and obstacleswere foundsuch as religion, workinghours, income, fear of legal issues, condom protection knowledge, STI symptoms knowledge,transmission route knowledge, fear of breaching confidentiality, fear of stigma, and fear of partner and family responses.
ISLAM AND GREEN TECHNOLOGY
Authors:   Research Institute for Islamic Products & Civilization (INSPIRE), Universiti Sultan Zainal Abidin, Gong Badak Campus, 21300 Kuala Nerus, Terengganu., Zaidin Mohamad Mohamad , Che Noh Noorsafuan ,   Research Institute for Islamic Products & Civilization (INSPIRE), Universiti Sultan Zainal Abidin, Gong Badak Campus, 21300 Kuala Nerus, Terengganu., Faiz Hakimi Mat Idris Mohd ,   Faculty of Islamic Contemporary Studies, Universiti Sultan Zainal Abidin, Gong Badak Campus, 21300 Kuala Nerus, Terengganu., Fauzi Hasan Ahmad ,   Faculty of Islamic Contemporary Studies, Universiti Sultan Zainal Abidin, Gong Badak Campus, 21300 Kuala Nerus, Terengganu., Yusof Sofyuddin ,   Faculty of Islamic Contemporary Studies, Universiti Sultan Zainal Abidin, Gong Badak Campus, 21300 Kuala Nerus, Terengganu., Abdullah Berhanundin ,   Faculty of Islamic Contemporary Studies, Universiti Sultan Zainal Abidin, Gong Badak Campus, 21300 Kuala Nerus, Terengganu.
Published: June 2023

Islam is a religion that emphasizes the importance of protecting the environment and preserving the earths natural resources. With the rise of global warming and climate change, the need for green technology has become more pressing than ever before. This study aims to identify the Islamic perspective and implementation of such programs in Islamic history, especially during the era of Andalusia. This study is a qualitative approach with a research design of document analysis. The studys findings show some of the green technologies that are compatible with Islamic principles, such as renewable energy sources and sustainable agriculture. Finally, the article concludes by highlighting the need for a holistic approach to environmental protection that integrates both Islamic teachings and modern green technologies.
LEGAL CONSEQUENCES OF AUTHENTIC DEED FORMATION BY LAND DEED OFFICIALS (PPAT) ON THE QUALITY OF THE POWER OF PROOF OF DEEDS AND THE PPATS CODE OF CONDUCT SANCTIONS IN THE REPUBLIC OF INDONESIA
Authors:   Master Student,FacultyofLaw,JenderalSoedirmanUniversity,Indonesia., Cahya Noviati Nurul , a Angkasa ,   Senior Lecturer,FacultyofLaw, JenderalSoedirmanUniversity, Indonesia., Sudrajat Tedi ,   Senior Lecturer,FacultyofLaw,JenderalSoedirmanUniversity,Indonesia.
Published: June 2023

Notary is a position of trust given by law to a notary who has been legally entrusted with making an authentic deed. The PPAT has the main task of carrying out some of the land registration activities by making deeds as proof that certain legal actions have been taken regarding land rights or ownership rights over flat units. Not infrequently the PPAT as a Public Official deals with criminal law processes such as being questioned as a witness or suspect in relation to the contents of the deed drawn up by him.One of the cases of forgery of authentic deed is the criminal case of forgery of authentic deed committed by PPAT namely in principle the defendant SA as PPAT has been charged with forging a letter in the form of deed of grant Number 15/2013 dated 12 December 2013 in the form of deed of grant for a plot of land from the grantor Mrs. . Tuminem and Mr. Sutikno to the beneficiary Mr. Riyanto. Based on this, there are interesting formulations of the problem. First, the legal consequences of fake authentic deeds on the quality of the strength of evidence for authentic deeds in Indonesia. The conclusion of the first problem is that the responsibilities of Notaries and PPATs in carrying out their profession require Notaries to always be careful and careful in every action they take. Second, apart from being subject to sanctions according to laws and regulations, PPATs will also be subject to sanctions in the PPAT Code of Ethics based on Article 4 letter (r) of the PPAT Code of Ethics where a PPAT has committed an act that violates the PPATs Code of Ethics.
SPECIFIC PURPOSE PRE-TRAINED CHATBOT FOR ENTERPRISE RELIABILITY ENGINEERING
Authors:   Head of the Department, Department of Information Technology, Sreenidhi Institute of Science and Technology, Yamnampet, Hyderabad., Bhutada Sunil , Naresh M. ,   Student, Department of Information Technology, Sreenidhi Institute of Science and Technology, Yamnampet, Hyderabad., Sai Satya Murthy P. ,   Student, Department of Information Technology, Sreenidhi Institute of Science and Technology, Yamnampet, Hyderabad., Sri Shourya K. ,   Student, Department of Information Technology, Sreenidhi Institute of Science and Technology, Yamnampet, Hyderabad.
Published: June 2023

With the increased interest of enterprises in finding reliability of their systems to work under different situations, resilience concept has got significant recognition. Reliability engineering is application of various principles, methods to make products work without any failure and in a cost efficient manner. Various parameters such as MTBF are used in calculating the failure rate of the system. The research is based on using pre trained model which uses API provided by the open AI. Open provides the API which is also used by chatgpt. Model responds to queries related to reliability of the system with help of a chatbot. Chatbot is an software application which mimics human like chats with the user. It is highly efficient and available which takes input in the form of text. The use of chatbot is increasing tremendously in various industries for various purposes. The popularity of Chat-GPT, which also uses the same Open AI API, has been rising dramatically in recent days. This AI-driven product has dominated the market and might be a huge help in providing responses to questions about resilience. As a result, to innovate and improve the dependability of systems, we have developed an implementation of ChatGPT. In this implementation, we will be utilizing natural language processing tools that will help us to boost user interaction by presenting innovative information about how systems function in various conditions.
SAFETY OF ANTI-OBESITY AGENTS IN ADULTS NARRATIVE REVIEW
Authors:   Kingdom of Saudi Arabia - Eastern Region - Al Ahsa., Hussain Al-Herz Intithar , Abdo Al-Dubai Sami ,   Kingdom of Saudi Arabia - Eastern Region - Al Ahsa.
Published: June 2023

Background: Weight management medications are appropriate treatment options for individuals who are overweight or obese and have been unable to achieve weight loss with lifestyle intervention alone. In this narrative review, we aimed to review the adverse effects and safety profile of anti-obesity agents in overweight and obese patients. Methods: PubMed database was were systematically searched for relevant studies published between January 2012 and July 2022 of randomized controlled trials phase II or III of anti-obesity agents, for adult 18 years old with overweight or obesity without diabetes mellitus or secondary causes of obesity.Studies that met eligibility criteria were extracted and reviewed. 48 studies were screened for eligibility, among them, 18 studies fulfill inclusion criteria and involved in the narrative review.
THE WISDOM OF SULTAN ZAINAL ABIDIN III IN DEALING WITH BRITISH INTERFERENCE IN TERENGGANU AFTER THE 1909 BANGKOK TREATY
Authors:   Research Centre for Arabic Language and Islamic Civilization, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia., Suryani Mat Resad Izziah , Azraai Jamsari Ezad ,   Research Centre for Arabic Language and Islamic Civilization, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia.
Published: June 2023

The Kingdom of Siam relinquished its authority over Terengganu to the British Government through the Bangkok Treaty of 1909. However, since Sultan Zainal Abidin III did not assent to the draft of the 1902 Treaty, only British agents were stationed in Terengganu. Although only British agents were intended to be stationed in Terengganu, Sultan Zainal Abidin III did not want to accept the stipulations of the Bangkok Treaty and had taken cautious steps in accepting the placement of British officers. He refused to accept the placement of British agents and examined all the contents of the agreement drafted by the British. This study aims to examine the wisdom of Sultan Zainal Abidin III in dealing with the British Government interference in Terengganu state government affairs with the placement of a British officer of the rank of an agent after the Bangkok Treaty of 1909. This study used a qualitative research method with a historical approach. The results of this study found that Sultan Zainal Abidin III tried to avoid British interference of placing an officer in Terengganu. Although only an agent-ranking British officer was stationed in Terengganu, His Majesty refused to accept the stipulation. When he realised that he ought to accept the British agent in Terengganu, he tried to examine all the contents of the agreement which was aimed at reducing the jurisdiction and influence of the British agent in the administration of Terengganu.
Análise das prescrições de anti-hipertensivos em unidade da atenção primária à saúde do Distrito Federal
Authors: Barros Débora Santos Lula , Santos Fernanda Maria Carvalho dos , Teixeira Taíssa Béda
Published: June 2023

Os anti-hipertensivos estão entre os medicamentos mais prescritos nas Unidades Básicas de Saúde (UBS). Nesse contexto, o objetivo deste estudo foi analisar as prescrições de anti-hipertensivos em uma (UBS) da Região de Saúde Oeste do Distrito Federal. Trata-se de um estudo observacional, descritivo, transversal, com coleta de dados secundários. Foi realizada a análise de 1.500 prescrições, das quais somente 870 foram consideradas válidas. Os medicamentos mais prescritos foram a losartana, a indapamida, a hidroclorotiazida, o anlodipino e o atenolol. Os médicos foram os prescritores mais prevalentes, seguido pelos enfermeiros. Foram encontradas nas prescrições taxas superiores a 90% em relação à adoção da Denominação Comum Brasileira (DCB) e da Relação de Medicamentos Essenciais do Distrito Federal (Reme-DF). O estudo contribui para o levantamento de informações elementares para a qualificação da assistência farmacêutica na região de saúde estudada.
Research on deformation of valve slice of automobile shock absorber
Authors: Li Shisheng , Yuan Qiong
Published: June 2023

Based on the bending deformation theory of cantilever beam, the mathematical model of bending deformation of single valve slice under uniform load is proposed and deduced by using the microbeam element method (MEM). The accuracy and reliability of the mathematical model established by the MEM and the small deflection method (SDM) are verified through the finite element simulation comparison. The results show that the valve slice deformation mathematical model under uniform load established by using the deformation theory of the MEM is suitable not only for the small deflection deformation (SDD) but also for the large deflection deformation (LDD) of the valve slice, and can reflect the dynamic deformation characteristics of the valve slice more truly than the SDM, which provides a certain theoretical basis for the deformation study of single valve slice. At the same time, the mathematical model is used to simulate the deformation law of the valve slice when the thickness, inner radius and outer radius change. The conclusion provides technical support for the design and performance prediction of the shock absorber.
Building a business case for workplace menstrual hygiene management programs: a social cost–benefit analysis
Authors: Eaton Jacob C. , Bronsard Michelle , Radin Mark , Kaunda Christopher , Avni Michal , Krishna Aditi , Kincaid Mary
Published: June 2023

Inadequate menstrual health and hygiene (MHH) pose a great challenge for working women, affecting their productivity, job satisfaction, attendance, and advancement, and also have implications for their employers. Yet there has been little research to quantify the impacts of poor MHH conditions or to consider the value add of workplace MHH programs. As part of USAID's Water Sanitation and Hygiene Partnerships for Learning and Sustainability project, we conducted a social cost–benefit analysis (CBA) of the Menstrual Hygiene Management (MHM) in the Workplace Action Research, a 10-month intervention in private sector enterprises in Nepal and Kenya. The intervention aimed to determine if providing adequate MHM in the workplace contributes to women's economic empowerment, including improved business and social outcomes. This CBA of a workplace MHM intervention – the first of its kind – found a positive return for investing in workplace MHM programs. The average benefit–cost ratio in the base-case across factories in a 10-month intervention was 1.4, which increased to 2.3 when projected over 24 months. These early results of a pilot CBA on MHM in the workplace should serve as a call for greater attention by governments and businesses to the needs of menstruating women.
POLÍTICAS PÚBLICAS PARA A PRIMEIRA INFÂNCIA E SUA RELEVÂNCIA A PARTIR DA LEI Nº 13.257/16
Authors: Sales Callou Esmeraldo Paes Nadinne , Youji Minami Marcos
Published: June 2023

O presente artigo perscruta a questão das políticas públicas na primeira infância e sua relevância a partir do Estatuto da Primeira Infância editado no Brasil em 2016. Objetiva-se, a partir da análise histórica da evolução dos direitos infanto-juvenis até a edição do aludido marco legal da primeira infância, demonstrar a significativa importância que essa fase da vida humana detém em relação a toda a vida do indivíduo, nas suas inter-relações e ligações familiares e sociais.Também se colima analisar de que forma a Lei no 13.257/16 aborda as questões das políticas públicas pertinentes ao assunto em tablado. Para atingir os desideratos elencados, a pesquisa teórica desenvolve-se através das metodologias descritiva e explicativa. Os dados serão coletados através de revisão bibliográfica, sendo avaliados qualitativamente. Ao final, concluir-se-á que o estabelecimento e a execução profícuas de políticas públicas pelo Estado, sobretudo nas áreas da saúde e educação, voltadas à primeira infância pode influenciar decisivamente no desenvolvimento sadio e harmonioso de crianças e de adolescentes.
A POSSIBILIDADE DE UMA ABORDAGEM TERRITORIAL DAS POLÍTICAS PÚBLICAS COMO INSTRUMENTO PARA A EFETIVAÇÃO DO DIREITO À SEGURANÇA
Authors: Pereira de Carvalho Eliana , Sousa Mendes Larissa , Gomes Marques Filho Elvis
Published: June 2023

A questão da segurança pública é uma das que mais aflige nossa sociedade e uma das mais complexas para se solucionar, tendo em vista que exige a coordenação entre os diversos órgãos do poder público e entre esses e a sociedade, como enfatizado na própria Constituição Federal de 1988. O Estado tem implementado programas, operações básicas de aparelhamento, com o objetivo de equacionar o problema do aumento da violência. No entanto, mesmo diante da relevância desses investimentos, constata-se que isso tem sido insuficiente para o combate à criminalidade, uma vez que tem se entendido cada vez mais a complexidade dos fatores que interferem na ocorrência de um crime. Nessa perspectiva, entende-se necessário considerar a dinâmica do território, a partir dos seus distintos usos, como um ângulo heurístico geográfico que permite espacializar os fenômenos da violência e pensá-los articulados com as qualidades territoriais, dotando o território, como um fator relevante na busca por garantir o direito à segurança. A partir desse discernimento, o presente trabalho tem por escopo compreender como uma abordagem territorial das políticas públicas pode se constituir em uma possibilidade de instrumento para efetivação do direito fundamental à segurança pública, no caso específico do Estado do Piauí. O estudo realizado constitui-se em uma perspectiva interdisciplinar entre as áreas do Direito e da Geografia. Para atender aos objetivos deste estudo realizou-se uma pesquisa bibliográfica em livros, periódicos, artigos científicos, com base nos seguintes autores: Bucci (2002), Pamplona (2016), Antas Junior (2017), entre outros. Para balizarmos nossas análises buscou-se apoio nas categorias de análise do Território Usado e do Território Normado desenvolvidas pelo geógrafo Milton Santos (2006). Constatou-se que considerar a dinâmica do território, a partir dos seus distintos usos, como um ângulo heurístico geográfico que permite espacializar os fenômenos da violência e pensá-los articulados com as qualidades territoriais é um fator relevante na busca pela elaboração de políticas de segurança mais eficientes e coerentes com a realidade dos territórios.
The Cost of School Set for the First-Former in View of Poverty Problem in Russia
Authors: Proshin I. A. , Korobkova N. Yu.
Published: June 2023

The article analyzes the cost of school set for the first-former as an indicator of expenses spent on yearly child fittingup for school. The calculation of the first-former set was done on the basis of the standard list of goods fixed by Rosstat for each region with regard to annual price dynamics in 2006–2021. The results show that the cost of the set rises every year both in absolute figures and in relation to the regional living wage. At the same time estimation of the average per capita income of households without children, households with one, two, three and more children based on selective monitoring of population income in 2014–2021 showed that the cost of school set for the firstformer exceeded the average per capita income of families with children and the gap increases with the number of children. The obtained results prove the necessity to develop measures of social support of families with school children. In the article the authors study the effective regional measures of supporting such families and put forward approaches to their upgrading. The research can be useful for working-out measures aimed at cutting the poverty rate in entities of the country, as families with children are the most vulnerable in the context of risk of getting into poverty.
Organization Life Cycle and Key Methods of Enterprise Development in Current Practice of Management
Authors: Zhukova T. V.
Published: June 2023

While analyzing organization life cycle, stages of development and slump the article found out that the stage of restoration is similar to the stage of start, but it differs from the latter, as a new spiral of enterprise life cycle is formed with regard to previous developments, experience and work trends. After SWOT-analysis the necessity to use strategies of the pretender to leadership on market is assessed. Estimation of weak sides showed that the absence of advert materials for a store with a limited geography cannot foster successful product promotion. The simplest way to attract customers is to use social nets. Estimation of opportunities focuses on studying the product range. By comparing different products within one category of goods we can understand what is profitable to buy and which products should be rejected. The enterprise can increase profit, if it changes the product range, raises the purchase of popular positions and rejects illiquid goods. The mentioned indicators show that the enterprise being analyzed is competitive and acts as an active participant on market. Today its key goal is to expand market. The author underlines the importance of using measures aiming at changing enterprise life cycle stages with the help of tools of digital economy.
Endogenous Development as Strategic Resource of Agrarian Growth in Conditions of Global Challenges
Authors: Golubev A. V.
Published: June 2023

Each stage of the development requires correction of economic course, especially in conditions of global challenges. The period of orientation to external sources of growth at the expense of selling raw materials and power products abroad is over, thus it is necessary to pass over to endogenous development of Russian economy, especially agriculture. Information provided in the article gives evidence to a big share of exported resources in respect to the volume of their production or extraction. Four fifth of mineral fertilizers produced in the country is sold abroad, though home agriculture uses them in insufficient volume. Additional amounts of mineral fertilizers in Russian fields could increase the volume of food that is in demand on global markets. Power resources that cannot be used due to anti-Russian sanctions could be directed to internal needs, which could give an opportunity to convert them into goods with high added value. Putting resources that were not used by western countries in home economy can create extra capacities and extend taxation base, which could compensate for losses on foreign market. In agriculture priority shall be given to the development of local economy mobilizing local labour and material resources, which apart from production effect could provide opportunities for resolving a number of social and economic problems caused by big agricultural producers. The author came to the conclusion about the promising nature of endogenous development, which can ensure the quality of Russian economy growth and its agrarian sector.
Magnetosomes as Potential Nanocarriers for Cancer Treatment
Authors: Alsharedeh Rawan , Alshraiedeh Nid’a , Aljabali Alaa A. , Tambuwala Murtaza M.
Published: June 2023

Magnetotactic bacteria (MTBs) and their organelles, magnetosomes, are intriguing options
that might fulfill the criteria of using bacterial magnetosomes (BMs). The ferromagnetic crystals contained
in BMs can condition the magnetotaxis of MTBs, which is common in water storage facilities.
This review provides an overview of the feasibility of using MTBs and BMs as nanocarriers in cancer
treatment. More evidence suggests that MTBs and BMs can be used as natural nanocarriers for conventional
anticancer medicines, antibodies, vaccine DNA, and siRNA. In addition to improving the stability
of chemotherapeutics, their usage as transporters opens the possibilities for the targeted delivery of
single ligands or combinations of ligands to malignant tumors. Magnetosome magnetite crystals are
different from chemically made magnetite nanoparticles (NPs) because they are strong single-magnetic
domains that stay magnetized even at room temperature. They also have a narrow size range and a uniform
crystal morphology. These chemical and physical properties are essential for their usage in biotechnology
and nanomedicine. Bioremediation, cell separation, DNA or antigen regeneration, therapeutic
agents, enzyme immobilization, magnetic hyperthermia, and contrast enhancement of magnetic resonance
are just a few examples of the many uses for magnetite-producing MTB, magnetite magnetosomes,
and magnetosome magnetite crystals. From 2004 to 2022, data mining of the Scopus and Web
of Science databases showed that most research using magnetite from MTB was carried out for biological
reasons, such as in magnetic hyperthermia and drug delivery.
WITHDRAWN: Exploring the Nutritional, Biochemical, and Phytoceutical Attributes of Pumpkin and its Utilization in Ready-to-Serve and Ready-to-Eat Products
Authors: Mittal Karan , Bakshi Manish , Rasane Prasad , Manhas Neha , Sharma Himanshi
Published: June 2023

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been
withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php.

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Triglyceride, an Independent Risk Factor for New-Onset Hypertension: A
Perspective
Authors: Goto Kenichi
Published: June 2023

Hypertension is the most important risk factor for cardiovascular disease worldwide. Alt-hough the pathogenesis of hypertension is complex and multifactorial, obesity-related hypertension has become a major focus of attention because of the continued increase in the prevalence of over-weight and obesity. Several mechanisms have been suggested to underlie obesity-related hypertension, including an increase in sympathetic nervous system activity, an upregulation of the renin-angiotensin-aldosterone system, alterations in adipose-derived cytokines, and an augmentation of insulin re-sistance. Emerging evidence from observational studies (including those using Mendelian randomiza-tion)suggests that the presence of high triglycerides, which is a common comorbidity in obesity, is an independent risk factor for new-onset hypertension. However, little is known about the mechanisms underlying triglyceride-associated hypertension. We summarize the existing clinical evidence that has demonstrated the adverse effect of triglycerides on blood pressure, and we then discuss possible un-derlying mechanisms based on the evidence from animal and human studies, with a particular focus on the roles of endothelial function, white blood cells, i.e., lymphocytes, and pulse rate.