bluuebunny/crossref_metadata_2025 huggingface dataset:
Epistemologia do turismo
Authors: De Queiroz Barbosa José William , Araújo Mayanne Fabíola Silva , Nóbrega Wilker Ricardo de Mendonça
Published: August 2022

Este estudo se propõe a apresentar uma revisão sistemática das produções acadêmicas voltadas ao aspecto científico e epistemológico do turismo. Para tanto, adotou-se abordagem qualitativa com aporte da revisão sistemática da literatura. A coleta de dados se deu por meio das plataformas "Publicações de Turismo" e "SciELO", utilizando o procedimento ProKnow-C. A amostra final da pesquisa foi de 26 artigos sobre o tema discutido, que foram tratados com auxílio da análise de conteúdo (Bardin, 2011), a partir de categorias analíticas pré-estabelecidas. Como principais resultados, percebeu-se que, no viés epistemológico do turismo, há uma estreita relação com a criticidade, ou seja, examinar as bases epistemológicas e a realidade do turismo de forma crítica e questionadora, além de utilizá-la para realizar pesquisas mais sólidas. No tocante à cientificidade do turismo, alguns autores também mencionam o aspecto crítico e notou-se uma preocupação em tornar os estudos na área favoráveis à sociedade como um todo, ultrapassando as barreiras dos muros da universidade. O turismo é um campo de estudo relativamente novo, com bases científicas em processo de consolidação. Entretanto, as análises demonstraram que os pesquisadores estão em busca do desenvolvimento de pesquisas sobre o caráter epistemológico e científico da área há mais de 15 anos. Este estudo traz contribuições à comunidade acadêmica do turismo ao apresentar um panorama das pesquisas relacionadas ao tema discutido, o que pode auxiliar na continuidade de investigações visando aproximar-se da criação de teorias e metodologias próprias do turismo.
Traditional Medicinal Plants: Safe and Efficacious Potential Drugs in the Management of Rheumatoid Arthritis
Authors: Nalla Sarath , Prasad Sahdeo , Kavuri Lakshmi , Pendyala Vijetha
Published: August 2022

Rheumatoid Arthritis is an autoimmune, chronic inflammatory disorder that
affects the synovial tissues of the joints. Whilst the standard treatment regimen
involves non-steroidal anti-inflammatory drugs, disease-modifying antirheumatic
agents and glucocorticoids attenuate the symptoms. However, the long-standing use of
all these drugs causes adverse effects, which leads to the research on medicinal plants.
History shows that many medicinal plants are an integral part of various traditional
medicine systems, thus facilitating an alternative form of therapy in various parts of the
world. Since ancient civilization, many of the medicinal plants that used as popular
remedies are available abundantly in Asia. In this chapter, we are presenting the
information on various medicinal plants found in Asia that are reported to be having
anti-arthritic activity. Scientific studies revealed that herbs exert beneficial effects in
treating arthritis by numerous cellular mechanisms, including downregulation of pro.inflammatory cytokines like TNF-α, IL-6, and NF-κB, oxidative stress suppression,
suppression of cartilage degradation with degradative metalloproteinases, and
increasing antioxidant performance. A variety of phytoconstituents from diverse
chemical categories such as flavonoids, lignans, coumarins, terpenes, glycosides,
phytoestrogens, sesquiterpene lactones, anthraquinones, alkaloids, and thymoquinone
are extracted from these medicinal plants. Additionally, in this chapter, the
pharmacological actions of these plants were also discussed.
Preclinical and Clinical Studies on Natural Products Used in Rheumatoid Arthritis
Authors: Kamboj Anil , Singh Randhir
Published: August 2022

Rheumatoid Arthritis (RA) is a chronic autoimmune disease with unknown
etiology, characterized by progressive cartilage erosion leading to joint distortion and
polyarthritis. Rheumatoid arthritis significantly affects the quality of life.
Approximately 1% population of the world suffer from rheumatoid arthritis, and
prevalence of RA is increasing day by day. There are many synthetic compounds
available for the management and treatment of rheumatoid arthritis but,- these
therapeutic agents have significant side effects like diarrhea, rashes, alopecia,
stomatitis, infrequent myelosuppression, hepatotoxicity and other toxicities. Moreover,
symptoms can reappear after discontinuation of the therapy. Because of these side
effects, and limitations of the existing synthetic drug, patients are shifting their interest
from synthetic to natural products for the treatment well as management of rheumatoid
arthritis.This chapter gives an overview of several plants having medicinal properties
with a potent therapeutic value that can be used for the management of rheumatoid
arthritis.
Re-contextualising advertising through re-creation: the recycling and translation of advertisements in the context of the COVID-19 pandemic
Authors: Cantarero Muñoz María
Published: August 2022

The COVID-19 pandemic completely reconfigured the semiotic landscape. When the crisis was at its height, a whole series of words, images and sounds (or their absence) became representative symbols of the context we found ourselves in, not only in the media, but also in public and private spaces. This article analyses how these semiotic systems were renegotiatedin order to acquire new meanings in the context of the COVID-19 pandemic. It takes as a case study two Coca-Cola brand advertisements based on the same creative idea, which circulated in 2002 and 2020 respectively. Through a comparative analysis of the elements that make up each version of this multimodal text, it shows how the original advertisement was semiotically translated in order to adapt it to the needs of a new target context (the pandemic situation). We conclude that concepts drawn from intersemiotic and audiovisual translation studies can help shed light on these processes of recontextualization and meaning reconstruction in the case of multimodal texts.
Commercial and fan subtitling of the pilot episode of the TV series Fargo (2014): descriptive and comparative analysis
Authors: Guimarães Carlos
Published: August 2022

: This article carries out a comparative study of the commercial and fan subtitling of the same source text, namely “The Crocodile’s Dilemma”,the pilot episode of the TV series Fargo (2014). The aim is to ascertain the commonalities and divergences between these two different types of translation with regard to European Portuguese. It seeks to verify if the usual tendency of commercial subtitling being domesticating and fan subtitling foreignizing applies in Portugal or if Portugal deviates from this pattern. Furthermore, the herein article shall also focus on other translational matters outside the domestication and foreignization aspects, although with a bit less coverage. The attention will also shift toward the tackling of taboo language and omission of verbal information between commercial and fan subtitling, with commercial subtitling being typically associated with censorship and omissions, whilst fan subtitling is usually known for its uncensored all-inclusive version. Naturally, the case study of a single pilot episode cannot permit encompassing conclusionsto be drawn, but it can provide a peek into the commercial and fan subtitling phenomena in Portugal in order to get a preliminary idea of how it compares to the rest of the world.
A localization tale: localization of a videogame named Sofia and the Barbarian - A Kid's Tale
Authors: Gonçalves Heidy
Published: August 2022

In this paper, the practice of videogame development, translation and localization is explored, taking as a case-study an independent videogame created through a collaborative family project -Sofia and the Barbarian –a Kid’s Tale.1The paper explores the possible relation between the translation approaches used in the field and the promotion of a videogame on social networks, websites and platforms (itch.io). The findings are likely to be of interest not only to videogame lovers, but also independent videogame creators, translators, and translator trainers.
O uso do memoQ nas tarefas de pré-tradução: revisão crítica de funções e sugestões de melhoria
Authors: Chaves Tatiana Limongi
Published: August 2022

O presente artigo apresenta sugestões de melhorias e novas funcionalidades para o memoQcom o objetivo de conseguir um ambiente tecnológico integrado e abrangente de tradução, que inclua funções de pré-tradução. As melhorias sugeridas são baseadas em observações de campo feitas durante um estágio numa empresa de tradução. A análise das funções concentra-se nas tarefas de pré-tradução por ter sido a fase em que mais constrangimentos foram encontrados, enquanto as sugestões abrangem várias etapas do ciclo de tradução.
FAMILIA BORAGINACEAE
Authors:   Instituto Politécnico Nacional, Patiño Siciliano Alfredo
Published: August 2022

Familia de aproximadamente 90 géneros y unas 2000 especies, no pocas veces arvenses; se distribuye ampliamente en los dos hemisferios. En el área de la presente Flora se registran 15 géneros y 53 especies.
FAMILIA ATHYRIACEAE
Authors:   Universidad Autónoma Metropolitana-Iztapalapa, Pacheco Leticia ,   Universidad Autónoma Metropolitana-Iztapalapa, Guzmán Cornejo Laura
Published: August 2022

Familia monofilética de helechos con aproximadamente 650 especies clasificadas en tres géneros: Athyrium Roth, Deparia Hook. & Grev. y Diplazium Sw. Se distribuyen en zonas templadas y tropicales. Para la región de estudio se registran dos géneros: Athyrium con tres especies y Diplazium con cuatro.
Challenges Facing the Use of Point Of Sale POS from Merchants and Banks’ Employees Perspective in Sudan
Authors: Hassan Khattab Ishraga Abdelhafiz , Ahmed Bushra Salah Abdelkareem , Omarabi Omer Hassan
Published: August 2022

This study aims to identify challenges facing the use of POS in Sudan from the perspectives of merchants and banks’ employees. An Exploratory study was applied to capture the perspective of the merchants using questionnaires to collect data on their views, while a qualitative technique using focus group was adopted to collect data on banks employees’ perception on challenges facing POS in Sudan. (150) questionnaires were distributed in Khartoum. Ultimately (141) responses were received and checked for completeness and consistency and were randomly cross checked for accuracy of the data. (100) banks’ Employess from the marketing and IT departments participated in the focus group discussion.Based on the merchants ‘perspective the main challenges facing the use of use of POS in Sudan is the legal and regulatory hurdles followed by operational challenges including poor network reliability. Banks’ employees perceive that the challenges are manifested in the lack of (know how) in addition to the need to develop an incentive plan that encourages customers to use POS more often. The study recommends that further investment should be put in the network and the IT infrastructure in addition to the need to revisit the regulatory procedure governing the relationship between the different stakeholders of POS. Larger sample size to be employed.
Study of Physico- Chemical Parameters of Sugar Industry Effluent
Authors: Kakade V. B.
Published: August 2022

Sugar mill effluents are responsible for deterioration of water quality, due to effluents physical and chemical characteristics of river water changes and become unfit for human consumption. The present study was undertaken on the physico-chemical parameters of Bhima-Patas sugar industry effluent in Daund Tahsil. The study was conducted during 2009-2012 in crushing season of sugar industry. During the study period we recorded the different Physical as well as chemical properties of sugar mill effluent like Temperature, pH, TSS, TDS, Hardness, BOD, COD, DO, SO4, PO4, Oil and Grease, Zn, Hg etc. The result from the analysis of sugar industry waste water (effluent) shows that most of the parameters were much higher than the Minimum Pollution Level (MPL). Hence the flow of this effluent into the river causes serious pollution problems for aquatic life as well as human and livestock.
A Transmission Electron Microscopic Study of the Olfactory Epithelium in Hill Stream Cyprinidiae, Garra mullya (Sykes)
Authors: Bagade R S , Suresh DVNS
Published: August 2022

Olfaction is primarily produced by the stimulation of receptor cells on the olfactory organ's neuroepithelial surface, surrounded by olfactory nerve fibres. Numerous fish life processes, including migration, communication, feeding, schooling, defence, and reproduction, depend heavily on olfactory signals and cues. The olfactory and reproductory systems are interconnected structurally and functionally, and puberty-related alterations in the olfactory epithelium are documented. The olfactory epithelium, which covers a large portion of the surface of the olfactory rosette, a structure found within the olfactory chambers on the fish rostrum, is where the olfactory receptor cells are situated. Although ultra structural transmission electron microscopic studies of the olfactory organ and bulb are carried out by some investigators but very sparse information is available on hillstream fishes and that is why this work has been undertaken to detail the structure of olfactory system in G. mullya by electron microscopy. Microvillous olfactory receptor cells are placed compactly adjacent to the supporting cell showing a junction complex : the zonula-ocludens. Polygonal white cells are present in between the basal cells and supporting cells. Small polyhedral basal cells lie just above the basal lamina of olfactory epithelium. Basal cells may be working as stem cells for regeneration of lost or damaged non sensory and goblet cells.
Equitable chromatic number of weak modular product of Some graphs
Authors: Kaliraj K. , Narmadha Devi R , Vernold Vivin J
Published: August 2022

An equitable coloring of a graph G is a proper coloring of the vertices of G such that the number of vertices in any two color clases differ by at most one. The equitable chromatic number χ=(G) of a graph G is the minimum number of colors needed for an equitable coloring of G. In this paper, we obtain the equitable chromatic number of weak modular product of two graphs G and H, denoted by G o H. First, we consider the graph G o H, where G is the path graph, and H be any simple graph like the path, the cycle graph, the complete graph. Secondly, we consider G and H as the complete graph and cycle graph respectively. Finally, we consider G as the star graph and H be the complete graph and star graph.
Acción pública y política pública para el desarrollo
Authors: Rodríguez Castillo Luis , Aguilar Ortega Teodoro , Sandoval Moreno Adriana , Paleta Pérez Guillermo , Díaz Anaya Alejandra , Rodríguez Castillo Luis , Nájera de León Emmanuel , Pérez Robledo Flor María , Rodríguez Castillo Luis ,   CIMSUR-UNAM, Zavaleta Lemus Marta Eugenia
Published: August 2022

En este grupo de trabajo se partió de considerar que el contexto de la llamada mundialización y el ascenso de las políticas neoliberales se han conjugado en nuestro país con políticas para la descentralización y el fortalecimiento del federalismo con alternancias electorales en los niveles nacional y local. Nos interesa encontrar explicaciones a la pregunta de por qué, desde la perspectiva de quienes impulsan esas medidas, se han generado en los últimos años importantes reformas en el desarrollo y la operación de las políticas públicas.
Hoy no circula (un día sin auto). El traslado en automóvil en la Ciudad de México como práctica Hoy no circula (A day without a car)
Authors: Cebey Montes de Oca Georgina
Published: August 2022

Este artículo examina la cinta Hoy no circula (un día sin auto) codirigida por Rafael Montero y Víctor Ugalde en 1993. Se indaga en las experiencias de movilidad motorizada en la Ciudad de México en lo general y, en particular, en el impacto que tuvo en los conductores la implementación del programa Hoy no circula, medida que, para disminuir la contaminación, limitó la circulación de los automóviles en la capital mexicana. Con ayuda del cine, se propone que el traslado a bordo de un automóvil constituye una práctica de lo cotidiano, que arroja luz sobre los usos y efectos que produce el espacio en el habitante.
Nuevas aportaciones a la vida y obra del Ing. Modesto C. Rolland
Authors: Winfield Reyes Fernando N.
Published: August 2022

En este libro, Justin Castro dedica una interesante crítica a la relación entre la construcción y puesta en marcha de propuestas técnicas y proyectos de obra de interés público, y las necesidades e ideas surgidas posteriormente a la Revolución mexicana, destacando el papel clave, pero en ocasiones poco estudiado, de la labor de la ingeniería y de los profesionales de esta disciplina.
Voice Cloning in Real Time
Authors: Naik Varad , Mendes Aaron , Kulkarni Saili , Naik Saiesh , Verlekar Saiesh Prabhu
Published: August 2022

Abstract: Deep learning models for natural voice cloning methods were first developed in 2016, and since then, the researchers' main attention has been on making the voice more realistic and obtaining the output voice in real time. Previously it used to take many hours of voice samples to clone a few seconds. It was decreased to a few seconds after utilizing deep learning models. We shall look at various voice cloning techniques in this paper. Multi-speaker generative models, speaker adoption, speaker encoding, vector quantization, and other techniques are among them
Resource theory of causal connection
Authors: Milz Simon , Bavaresco Jessica , Chiribella Giulio
Published: August 2022

The capacity of distant parties to send signals to one another is a fundamental requirement in many information-processing tasks. Such ability is determined by the causal structure connecting the parties, and more generally, by the intermediate processes carrying signals from one laboratory to another. Here we build a fully fledged resource theory of causal connection for all multi-party communication scenarios, encompassing those where the parties operate in a definite causal order and also where the order is indefinite. We define and characterize the set of free processes and three different sets of free transformations thereof, resulting in three distinct resource theories of causal connection. In the causally ordered setting, we identify the most resourceful processes in the bipartite and tripartite scenarios. In the general setting, instead, our results suggest that there is no global most valuable resource. We establish the signalling robustness as a resource monotone of causal connection and provide tight bounds on it for many pertinent sets of processes. Finally, we introduce a resource theory of causal non-separability, and show that it is – in contrast to the case of causal connection – unique. Together our results offer a flexible and comprehensive framework to quantify and transform general quantum processes, as well as insights into their multi-layered causal connection structures.
RELATIONAL SUBSTANTIATION OF THE HUBBLE LAW
Authors: Molchanov A. B
Published: August 2022

In recent years, within the framework of the relational approach to the description of space-time and physical interactions, a number of studies have been carried out to substantiate cosmological effects. It has been shown that the cosmological redshift and the cosmic microwave background may be the result of contributions from emitted but not absorbed radiation. However, until now, Hubble’s law has not been fully derived on the basis of only relational ideas. In this paper, this conclusion is presented and the Hubble parameter is calculated in the modern era. For this, the contributions of the pulses of the emitted but not absorbed radiation to the pulse of a distant astronomical object (cluster of galaxies) are considered. It is shown that taking these contributions into account leads to the linear Hubble law.
PHYSICS OF NUMERICAL RELATIONSHIPS
Authors: Müller H.
Published: August 2022

An approach to the problem of stability of systems of a large number of bound periodic processes is proposed, based on the physical interpretation of certain statements of number theory. Possible applications of this approach to the physics of planetary systems, astrophysics, elementary particle physics and biophysics are considered.
Diferentes sentidos da eugenia galtoniana interpretados por Renato Kehl durante a campanha eugênica brasileira
Authors: Carvalho Leonardo Dallacqua de
Published: August 2022

O objetivo deste artigo é demonstrar como o conceito de eugenia proposto por Francis Galton transitou por diferentes entendimentos na interpretação do eugenista brasileiro Renato Kehl. Para tanto, trabalhamos com quatro obras a fim de, colocando-as lado a lado e compreendendo seus contextos de produção a partir das leituras de Kehl, analisar como o conceito elaborado por Galton foi reinterpretado pelo eugenista brasileiro em diferentes fases da campanha eugênica. Assim, Eugenia e Medicina Social (1922), Melhoremos e Prolonguemos a vida: a valorização eugênica do homem (1923), Lições de Eugenia (1929) e Aparas eugênicas: Sexo e civilização (1933), constituem as fontes principais desta pesquisa.
Circulações, trânsitos e hibridismos: quadrinhos nas Américas em perspectiva transnacional
Authors: Gomes Ivan Lima , Gandolfo Amadeo
Published: August 2022

Esboçar uma definição de história em quadrinhos é uma tarefa inglória. À historiografia cabe, antes, investigar suas manifestações em diferentes contextos, apresentando abordagens que possibilitem interpretá-las historicamente e ressaltando os diversos usos possíveis desta expressão gráfica. Exploramos aqui o estudo dos quadrinhos informado por um olhar atento às circulações e trânsitos envolvendo artistas e obras, sem ignorar suas implicações no campo dos imaginários e das representações. Em outras palavras, se, por um lado, uma série de temas em torno das operações de deslocamentos se impõe um como tema de pesquisa, por outro lado tais discussões sugerem que reflitamos sobre como tais deslocamentos podem ser representados e mesmo se constituem enquanto um componente central da própria estética dos quadrinhos. Fragmentada e marcada pela articulação de imagens em sequência, os quadrinhos possibilitam aprofundar o debate sobre o transnacional, por meio de tópicos envolvendo os trânsitos e as transações culturais em seus diversos níveis. Buscamos analisar tais caminhos a partir de uma análise bibliográfica, refletindo sobre os caminhos que levaram à organização do dossiê "Quadrinhos nas Américas em perspectiva transnacional"
Cardiovascular risk assessment in divers: Toward safer diving
Authors:   University Medical Center Utrecht, The Netherlands, Rienks Rienk ,   CardioExpert Clinic for Sports and Occupational Cardiology, Amsterdam, The Netherlands, Buwalda Mattijn ,   Medical and Educational Services, Odijk, The Netherlands, Bucx Jeroen ,   CardioExpert Clinic for Sports and Occupational Cardiology, Amsterdam, The Netherlands, Dubois Emile ,   Hyperbaric Medical Center, Rijswijk, The Netherlands, Wingelaar Thijs ,   Royal Netherlands Navy Diving and Submarine Medical Center, Den Helder, The Netherlands,   Amsterdam University Medical Center, Academic Medical Center, Department of Hyperbaric Medicine and Experimental Anaesthesiology, Amsterdam, the Netherlands, van Hulst Rob ,   Amsterdam University Medical Center, Academic Medical Center, Department of Hyperbaric Medicine and Experimental Anaesthesiology, Amsterdam, the Netherlands
Published: August 2022

Similar to aviation, diving is performed in an environment in which acute incapacitation may lead to a fatal outcome. In aeromedicine, a pilot is considered “unfit to fly” when the cardiovascular event risk exceeds one percent per annum, the so-called 1% rule. In diving no formal limits to cardiovascular risk have been established. Cardiovascular risk of divers can be calculated using the modified Canadian Cardiovascular Society (CCS) Risk of Harm formula: risk of harm (RH: cardiovascular fatality rate per year during diving: number × 10-5 divers/year) = time diving (TD: number of dives × 10-4) × sudden cardiac incapacitation (SCI: cardiovascular diver event rate per year (number × 10-5/year). The SCI and thus the RH are strongly dependent on age. Using the CCS criterion for RH, 5 × 10-5 divers/year, and considering an average of 25 dives per year per diver, the calculated maximum acceptable SCI is 2%/year, consistent with current practice for dive medical examinations. If the SCI were to exceed 2%/year, a diver could be considered “unfit to dive,” which could particularly benefit older (≥ 50 years) divers, in whom cardiovascular risk factors are often not properly treated. For the prevention of fatal diving accidents due to atherosclerotic cardiovascular disease, a dive medical examination is of limited value for young (<50 years) divers who have no cardiovascular risk factors. Introducing a cardiovascular risk management system for divers may achieve a reduction in fatal diving accidents that result from cardiovascular disease in older divers engaged in both recreational and professional diving.
Is Cytoreductive Nephrectomy Still Beneficial for Patients With Metastatic Renal Cell Carcinoma in the Contemporary Immunotherapy Era?
Authors: Choi Jae Duck , Cho Jeong Man , Yoo Tag Keun
Published: August 2022

Cytoreductive nephrectomy (CN) has long been the standard of care for patients with metastatic renal cell carcinoma (mRCC) since 2 clinical trials revealed its role during the cytokines era. With discovery of novel and effective drugs, such as vascular endothelial growth factor-targeted therapies, the role of CN started to be challenged. The 2 recent prospective randomized trials Cancer du Rein Metastatique Nephrectomie et Antiangiogéniques (CARMENA) and Immediate Surgery or Surgery After Sunitinib in Treating Patients with Metastatic Kidney Cancer trial (SURTIME) have changed the therapy paradigm for patients with mRCC. The CARMENA trial was performed to reveal whether CN is required in the targeted therapy, whereas SURTIME evaluated whether initial sunitinib can aid in the selection of patients who are most likely to benefit from subsequent CN or identify patients with innate resistance to targeted therapy. These trials suggest that CN does not provide a survival benefit for patients with poor‑risk disease. Especially, current evolutions in systemic therapies have demonstrated improved oncological outcomes from immunotherapy (IO) such as immune checkpoint inhibitor, particularly in its combination or combination with tyrosine kinase inhibitor. Accordingly, the role of CN continues to be questioned. Taken together, these findings reinforce the concept that the ultimate impact of CN on oncologic outcomes of mRCC patients in the era of IO still needs further investigation to represent a key for unmet clinical need.
Characteristics of Patients Who Visit Urologic Outpatient Department via Health Promotion Center
Authors: Ko Jong Cheol , Lee Kwang Suk , Yoo Jeong Woo
Published: August 2022

Purpose: Health examination is one of the methods to make the diagnosis of benign prostatic hyperplasia. To evaluate factors leading to the visit to the outpatient department (OPD) in patients at the health promotion center (HPC) who did not undergo urology treatment.Materials and Methods: This observational study was based on data from an HPC database of 2,700 patients who underwent transrectal ultrasound between March 2018 and February 2021. Of these, 264 patients visited OPD. Factors affecting OPD visits, such as colonoscopy at HPC and daily fluid intake, were evaluated. Logistic regression analysis was used to identify the independent risk factors to predict the visit to OPD.Results: Age (p<0.001) and diagnosis of overactive bladder (p<0.001) were significantly correlated with the severity of the total International Prostate Symptom Score (IPSS); however, colonoscopy evaluation at HPC and daily fluid intake did not correlate. Prostate volume (PV) (p=0.002) and total IPSS (p<0.001) were identified as predictive factors for the visit at OPD via HPC. The cutoff value of total IPSS and PV were 12 points and 26.7 cm3. The total IPSS (8–11) at HPC group presented higher total IPSS at OPD and the total IPSS (12–19) at HPC group showed lesser total IPSS at OPD (1.9±2.8 vs. -1.0±4.2, p=0.008).Conclusions: Twelve or more total IPSS is a significant factor that determines the OPD visit. At HPC, the primary care physician should be considered to recommend OPD to patients who have 12 or more total IPSS and 26.7 cm3 or more PV at the same time.
MAKNA SIMBOL-SIMBOL DALAM KUMPULAN PUISI MATA AIR DI KARANG RINDU KARYA TJAHJONO WIDARMANTO
Authors: Setiawan Kodrat eko putro , Wahyuningsih Wahyuningsih , Kasimbara Devi Cintia
Published: August 2022

Penelitian ini membahas kumpulan puisi Mata Air Di Karang Rindu karya Tjahjono Widarmanto menggunakan pendekatan semiotika. Pendekatan ini merupakan upaya mengungkap tanda yang terdapat dalam kumpulan puisi berupa simbol. Tujuan penelitian ini adalah mendeskripsikan simbol budaya dan simbol sastra. Metode yang digunakan adalah deskriptif kualitatif dengan teknik pengumpulan data: mengumpulkan, membaca, dan mempelajari buku yang berhubungan dengan penelitian. Hasil pembahasan menunjukkan bahwa terdapat simbol budaya yang meliputi bahasa, benda, warna, dan tindakan. Simbol sastra berupa citra penglihatan, gerak, dan pendengaran. Simbol bahasa digunakan untuk menampilkan istilah-istilah dalam mempertegas dan memperjelas sifat religius. Simbol bahasa juga mengandung amanat selalu mengingat kematian yang pasti akan dialami semua makhluk hidup. Simbol sastra berupa citraan digunakan untuk mengimajinasikan kematian sehingga pembaca memiliki gambaran dalam pikirannya tentang proses kematian yang menjadi ketetapan dari Tuhan.
Realidades emergentes: una mirada desde la comunicación educativa
Authors: Puentes Castro Luis Miguel , Gómez Palacio Estiwar , Cárdenas Ramírez Nancy Eugenia , Guerrero Mogollón María de los Ángeles , Pérez Ruiz Sergio Andrés , Posada Vega Vicente , Montoya Galeano Gustavo Adolfo , Olaya Vanegas César Augusto , Santa Ayala Diego Alejandro , Correa Cortés José Santiago , Bedoya Olga Lucía , Cardona Arce Luz Ángela
Published: August 2022

En la diversidad de temáticas compiladas en este documento, se encuentran tres elementos que se entretejen formando una unidad. La visión de los autores de observar sus fenómenos desde la transformación y el cambio, ya sea porque se utilizan marcos de referencia que iluminan ese dinamismo, o por el surgimiento de campos de estudio que requieren mover las concepciones con que se observaron esas temáticas anteriormente. El uso de la metodología cualitativa coherente con dicha visión, en la medida que su enfoque considera que la realidad es una construcción social, donde los seres humanos somos quienes creamos y transformamos ese entorno. Y la conjugación de lo anterior, lleva a los autores a hallazgos que son pistas de realidades emergentes que son dignas para tener en cuenta en la comprensión de esas nuevas realidades y en cualquier intervención social que aborde esos fenómenos estudiados. Esperamos que disfruten los trabajos expuestos y que puedan replicar muchos elementos de los mismos, en sus investigaciones particulares. Cualquier pedazo de realidad contiene signos que merecen ser leídos con seriedad para transformar positivamente nuestro alrededor. Esa es la apuesta.
Comparative Analysis of Heat Transport Improvement Using Water and Ethylene Glycol Based Magnetized Nanoparticles Through Darcy-Forchheimer Porous Space with Various Features
Authors: Nasir Saleem
Published: August 2022

This study focuses on the comprehensive analysis of thermal
characterization of an electrically conducting nanofluid flow containing
TiO2 nanoparticles dissolved in two different common liquids (H2O and
C2H6O2) and contained within a continuously extending disk. The heat and
concentration formulation are modified by incorporating the standard
interpretations of the Joule heating, energy source, dissipation, and
modified activation energy with binary chemical reactions. The
Darcy-Forchheimer addition are used to highlight the significance of
porous media. The Brownian dispersion’s effects are clearly discernible
in the current investigation. Furthermore, as a novelty, special
thermophysical models of viscosity and thermal conductivity are
included. The obtained differential formulations are tackled through
analytical procedure HAM. The veracity of finding is verified through
numerical scheme (ND-solve technique). Using several graphs and charts,
the perception trends of model factors are evaluated. The influence of
and are estimated based on flow characteristics. The drag force and heat
transmission rate are shown to optimize with as well as in the pictorial
simulations produced from the existing model. The can also be
strengthened by the presence of a high degree . The outcomes are
validated by previous studies and a good degree of consistency is
revealed.
Regularity of weak solutions for the relativistic Vlasov-Klein-Gordon system
Authors: Xiao Meixia , He Yingxi
Published: August 2022

This article is devoted to the study of the relativistic
Vlasov-Klein-Gordon system in space dimension three. The dynamical model
describes a collisionless ensemble of classical particles coupled with a
Klein-Gordon field. By combining the Fourier method and smoothing effect
of low velocity particles, we prove a higher regularity of the field,
which is widely used for the study of Vlasov equation.
A new approach for non-Gaussian vibration analysis of hyperbolic tangential package
Authors: Yang Song-Ping , Su Ri-Qing , Wang Zhi-Wei , Chen Yu
Published: August 2022

A new approach is proposed to analysis the non-Gaussian random vibration
of hyperbolic tangential package. Firstly, the non-Gaussian vibration
noise of specified mean, variance, skewness and kurtosis is developed by
Hermite polynomial, and verified by Gaussian mixture model (GMM) theory.
Secondly, next to analyzing an analytical and numerical response of the
two degrees of freedom (TDOF) linear package, the acceleration response
of the TDOF hyperbolic tangential package system (HTPS) under
non-Gaussian vibration excitation is obtained though the Hermite
polynomial and Runge-Kutta method, and the effects of the external
excitation and system parameters are investigated. Finally, on the basis
of the first-passage probability of the acceleration response, the
reliability analysis method is introduced. The analysis provides a
guidance to the vibration reliability analysis and packaging
optimization design.
Single-center experience of LVAD implantation in patients with sickle-cell trait: a retrospective analysis
Authors: Grasso Elena , Khamees Khalid Al , Ibrahim Ahmed , abdallah hassane , Ibrahim Mohammed , Sayin Omer , Lorusso Roberto
Published: August 2022

Background: The most worrisome complications in patients
supported by left ventricular assist device (LVAD) are pump thrombosis,
embolism, and bleeding. The actual rate of these events in patients with
sickle-cell disease (SCD) has not well investigated. The aim of our
study is to evaluate the outcomes of LVAD implantation in patients with
sickle-cell hemoglobinopathy at our institution. Methods: This
retrospective, observational, single-center study was conducted on
patients with sickle-cell trait (SCT), who underwent LVAD implantation
using the HeartMate3 LVAD. Results: LVAD devices were implanted
in four patients with SCT. All procedures were performed successfully.
All patients had uneventful post-implant course. Overall, the mean
follow-up time was 25 months (range 21-28 months) and showed an
unremarkable post-implant course. There was a significant improvement in
hematological markers over the follow-up period. Conclusions:
Despite the limited numbers of patients enrolled in this study, our
findings indicate that LVAD surgery is safe in SCD patients and offers
remarkable clinical improvement. Further studies are needed to provide
more evidence regarding this type of patients undergoing LVAD
implantation.
Vasoactive-Inotropic Score: A dilatory predictor of adverse short-term postoperative outcomes in pediatric patients undergoing cardiac surgical procedures with cardiopulmonary bypass.
Authors: Sainathan Sandeep , Mulinari Leonardo
Published: August 2022

The Vasoactive-Inotropic Score at 48 hours is a good surrogate marker
for adverse postoperative events in pediatric patients undergoing
cardiac surgery with cardiopulmonary bypass and is limited by its
ability to delineate the underlying cause for an unfavourable clinical
course. Thus, other predictors such as the Technical Performance Score
are likely to highlight the underlying cause and can be used to improve
outcomes. However, patients with a high postoperative VIS score at 48
hours may benefit from closer longer-term follow for outcomes such as
late survival, functional class, and need for reoperation.
Surgical Versus Transcatheter Aortic Valve Replacement: Impact of Patient-Prosthesis Mismatch on Outcomes
Authors: Alnajar Ahmed , Hamad Naser , Azhar Muhammad Z. , Mousa Yaseen , Arora Yingyot , Lamelas Joseph
Published: August 2022

Background: The hemodynamics of most prosthetic valves are
often inferior to that of the normal native valve, and a significant
proportion of patients undergoing surgical (SAVR) or transcatheter
aortic valve replacement (TAVR) have high residual transaortic pressure
gradients due to prosthesis–patient mismatch (PPM). Since the
experience with TAVR has increased and long-term outcomes are reported,
a close look at the PPM literature is required in light of new evidence.
Methods: For this review, we searched the Embase, Medline, and
Cochrane databases from 2000 to 2022. Articles reporting PPM as an
outcome following aortic valve replacements were identified and
reviewed. Results: The impact of PPM on clinical outcomes
aortic valve replacement has not been clear since multiple studies
failed to report PPM incidence. However, the PPM after SAVR vary greater
than after TAVR, ranging from 8% to almost 80% in SAVR and from
24%-35% in TAVR. Incidence of severe PPM following redo SAVR is
ranging from 2 to 9% and following valve-in-valve TAVR is from 14 to
33%, however, while PPM is higher in valve-in-valve TAVR, patients had
better survival rates. Conclusions: The gap between valve
performance and clinical outcomes in TAVR and SAVR could be reduced by
carefully selecting patients for either treatment option. Understanding
predictors of PPM can add to the safety, effectiveness, and increased
survival benefit of both TAVR and SAVR.
The use of Mee tree (Madhuca longifolia) in paddy cultivation by ancient Sri Lankans
Authors: Edirisinghe Sajith , Devmini Movini , silva Dulmini de , Pathmaperuma Shanaka , Ranasinghe Gamini
Published: August 2022

Agriculture has long been regarded as the backbone of Sri Lanka,
contributing to its’ economy for over thousands of years. However, with
recent technological advancements many of the indigenous practices with
regard to cultivation have been neglected or forgotten. The use of toxic
chemicals in agricultural practices has led to a host of deleterious
effects on humans as well as the environment. This paper looks into how
ancient Sri Lankans utilized a native tree, Madhuca longifolia (Mee), in
paddy cultivation for various purposes including the prevention of soil
erosion, water conservation, soil enrichment and pest control measures.
Although our ancestors lacked the scientific knowledge to justify their
practice, the basis for these are now understood in the scientific
community. Therefore, a return to these practices may be worthwhile in
terms of their beneficial influence on agriculture, environment and
human health and wellbeing. Keywords: Agriculture; Pest control; Soil
erosion; Conservation of natural resources
Child inflammatory myofibroblastic tumor of the kidney misdiagnosed as Wilms’ tumor : Case report
Authors: Bai Yu-feng , Liu Jing-zhong , Yue Li-na , Chen Li , Li Qiao-hong , Liu Sui-yi , Liu Rui
Published: August 2022

Renal Inflammatory myofibroblastic tumor (IMT) is very rare and lacks
characteristic clinical manifestation and radiographic features. This is
a case discussing the radiologic and pathologic findings of a renal IMT
in a 6-year-old boy who underwent radical nephrectomy for a right renal
mass that was misdiagnosed as Wilms’ tumor.
Treatment of unexplained facial numbness with stellate ganglion blockade: A case report
Authors: Imaizumi Uno , Beppu Satoshi , Sanuki Takuro
Published: August 2022

To date, there is no established treatment of facial numbness or
dysaesthesia of unspecified causes. Herein, we report a case of
unexplained facial numbness and confirmed hypaesthesia that achieved
clinical response to stellate ganglion blockade (SGB). SGB might be an
effective treatment of psychological-stress-related facial numbness of
unknown origin.
Is Baloxavir Marboxil the Answer to Treating Childhood Influenza?
Authors: Shaikh Omer , Fatima Sharmeen , Navaid Wardah , Shaikh Gulrukh , Nashwan Abdulqadir
Published: August 2022

Influenza A and B are the most common causes of respiratory
tract-restricted acute viral disease. Each year, it is estimated that
around 16% of children aged 5 to 17 are hospitalized. Baloxavir
Marboxil has the potential to be an innovative alternative to the
existing standard of therapy for these individuals.
Antituberculosis-drugs induced DRESS: A multidrug hypersensitivity or drug hypersensitivity relapse?
Authors: Mansour Khadija , Chadli Zohra , Fadhel Najah Ben , fredj Nadia Ben , Romdhane Haifa Ben , Chaabane Amel , Toumi Adnene , Aouam Karim
Published: August 2022

A 42-year-old female, treated with isoniazid, rifampicin, pyrazinamide
and ethambutol for multifocal tuberculosis, developed, forty days later,
hyperthermia, facial edema, cervical lymphadenopathy and generalized
exanthema. Biological test results revealed eosinophilia, atypical
lymphocytes, thrombocytopenia and liver injury. DRESS was suspected, and
four antituberculosis drugs (ATD) were withdrawn. As patch tests for the
four ATD showed negative results, we decided to reintroduce
pyrazinamide, ethambutol and rifampicin separately with a three-day
interval. Pyrazinamide and rifampicin were tolerated by the patient.
However, six hours after receiving ethambutol, she developed fever and
generalized rash, with no biological abnormalities, which resolved two
days later. Since ethambutol was claimed to be the culprit drug,
isoniazid was added, and 10 hours later, the patient developed fever,
facial edema, generalized rash, eosinophilia and liver injury. This
clinical and biological pattern resolved two weeks later. This report
suggests a hypersensitivity relapse to ethambutol after
isoniazid-induced DRESS in patients treated with first-line ATD.
The macro-anatomy of the vaginal outlet wall differs from the vaginal wall: A prospective, cadaveric case series study
Authors: Ostrzenski Adam
Published: August 2022

Objectives To describe and document the anatomical and histological
architecture of the vaginal outlet wall. Design A prospective
observational case series study. Setting International centers.
Population Twelve fresh human female cadavers. Methods Female corpses
were subjected to stratum-by-stratum, macro-, and micro-anatomical
dissections in sagittal, transverse, and coronal planes. Multiple
excisional biopsies were obtained from the vaginal outlet wall at 12, 3,
6, and 9 o’clock locations for histological examination. Digital
photograms documented the anatomical and histological features. Primary
Outcome measures gross, topographic anatomy and characteristic
histologic features of the vaginal outlet wall. Results The vaginal
outlet wall (VOW) was positioned in the vertical orientation and fused
with horizontally located the vaginal wall at the hymeneal plate level.
The hymeneal membrane and ring were not attached directly to the vaginal
wall. VOW has three identifiable anatomical-histological layers a) the
hymeneal membrane, b) the hymeneal ring (cartilage) with different
anatomy and histology than the vaginal wall, and c) the hymeneal plate
(the deep level of VOW), which connects to the vaginal wall. Conclusions
The vaginal outlet wall is an anatomical structure consisting of the
hymeneal membrane, hymeneal ring (cartilage), and hymeneal plate. This
structure is in vertical topographic orientation. Anatomically and
histologically, it differs from the vaginal wall, which fuses with the
deep layer of the hymeneal plate.
Expression of Inflammatory Cytokines and Acquired CFTR Dysfunction in Children with Rhinosinusitis：A Cohort Study
Authors: Liu Wenjing , Han Yang , Wang Pengpeng , Wang Tieshan , Qin Yu , Yang Xiaojian , Zhang Wei , Xiao Xiao , Tang Lixing , Ge Wentong
Published: August 2022

Abstract Objective: To explore the role of acquired CFTR dysfunction and
inflammatory chemokines in the development of rhinosinusitis in
children. Design and setting Twenty-five children who underwent
endoscopic sinus surgery for acute and chronic rhinosinusitis in the
Department of Otolaryngology Head and Neck Surgery at our hospital from
January 2021 to December 2021 were included. Whole blood, mucosa and
polyp tissues of all children were collected for study. Main outcome
measures： The CFTR gene was detected by using Full-length
second-generation sequencing. The expression of CFTR mRNA was measured
by qRT-PCR, and the expression of inflammatory chemokines was measured
by CBA. Results： There were 17 cases in the CRS group and 8 cases in
the ABRS group. The expression of CFTR mRNA in the mucosa of the ABRS
group was lower than that of the CRS group, and the expression of IL-6
and IL-8 in the mucosa of the ABRS group was significantly higher than
that of the CRS group. IL-6, IL-8 and MCP-1 were upregulated in polyps.
Conclusion: The dysfunction of acquired CFTR and the role of neutrophil
chemotactic factor are more obvious in ABRS, and may play a role in the
occurrence and development of CRS polyps.
Some Results on Prime Rings with Skew Symmetric Bi-Jordan Derivations
Authors: Şahin Zekiye Çiloğlu
Published: August 2022

A symmetric bi additive mapping $D$, on a prime ring $R$ is called
skew symmetric bi-Jordan derivation if it satisfies the following
condition associated with the automorphism of $\alpha $
of $R$:% \begin{equation*} D( x^{2},z)
=\alpha(x)D(x,z) +D(x,z)x
\end{equation*}% The purpose of this paper is to prove
some results concerning skew symmetric bi-Jordan derivation, as a
generalization of symmetric bi-Jordan derivation.
Type 2 diabetes, independent of obesity and age, is characterized by senescent and dysfunctional mature human adipose cells
Authors: Gustafson Birgit , Nerstedt Annika , Spinelli Rosa , Beguinot Francesco , Smith Ulf
Published: August 2022

Obesity with dysfunctional adipose cells is the major cause of the current epidemic of T2D. We examined senescence in human adipose tissue cells from age- and BMI-matched lean, obese and obese T2D individuals and found mature and fully differentiated adipose cells from obese and, more pronounced, from T2D individuals to exhibit increased senescence similar to what we previously have shown in the progenitor cells. Degree of adipose cell senescence was positively correlated with whole-body insulin resistance and adipose cell size. Adipose cell protein analysis revealed dysfunctional cells in T2D with increased senescence markers, reduced PPARγ, GLUT4 and pS473AKT. Consistent with a recent study, we found the cell cycle regulator cyclin D1 to be increased in obese cells but also further elevated in T2D cells, closely correlating with senescence markers, ambient donor glucose and, more inconsistently, with plasma insulin levels. Furthermore, fully differentiated adipose cells were susceptible to experimentally induced senescence, to conditioned medium increasing cyclin D1 and also responsive to senolytic agents. Thus, fully mature human adipose cells from obese and, more pronounced, T2D subjects become senescent and SASP secretion by senescent progenitor cells can play an important role in addition to donor hyperinsulinemia. 