bluuebunny/crossref_metadata_2025 huggingface dataset:
Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy
Authors: Tyberg Amy , Duarte-Chavez Rodrigo , Shahid Haroon M. , Sarkar Avik , Simon Alexa , Shah-Khan Sardar M. , Gaidhane Monica , Mohammad Tayyaba F. , Nosher John , Wise Susannah S. , Needham Victoria , Kheng Marin , Lajin Michael , Sojitra Badal , Wey Bryan , Dorwat Shivangi , Raina Hameed , Ansari Jaseem , Gandhi Ashish , Bapaye Amol , Shah-Khan Sardar M. , Krafft Matthew R. , Thakkar Shyam , Singh Shailendra , Bane Janele R. , Nasr John Y. , Lee David P. , Kedia Prashant , Arevalo-Mora Martha , Del Valle Raquel S. , Robles-Medranda Carlos , Puga-Tejada Miguel , Vanella Giuseppe , Ardengh Jose Celso , Bilal Mohammad , Giuseppe Dell'Anna , Arcidiacono Paolo G. , Kahaleh Michel
Published: May 2023

INTRODUCTION:

Cholecystectomy (CCY) is the gold standard treatment of acute cholecystitis (AC). Nonsurgical management of AC includes percutaneous transhepatic gallbladder drainage (PT-GBD) and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD). This study aims to compare outcomes of patients who undergo CCY after having received EUS-GBD vs PT-GBD.

METHODS:

A multicenter international study was conducted in patients with AC who underwent EUS-GBD or PT-GBD, followed by an attempted CCY, between January 2018 and October 2021. Demographics, clinical characteristics, procedural details, postprocedure outcomes, and surgical details and outcomes were compared.

RESULTS:

One hundred thirty-nine patients were included: EUS-GBD in 46 patients (27% male, mean age 74 years) and PT-GBD in 93 patients (50% male, mean age 72 years). Surgical technical success was not significantly different between the 2 groups. In the EUS-GBD group, there was decreased operative time (84.2 vs 165.4 minutes, P < 0.00001), time to symptom resolution (4.2 vs 6.3 days, P = 0.005), and length of stay (5.4 vs 12.3 days, P = 0.001) compared with the PT-GBD group. There was no difference in the rate of conversion from laparoscopic to open CCY: 5 of 46 (11%) in the EUS-GBD arm and 18 of 93 (19%) in the PT-GBD group (P value 0.2324).

DISCUSSION:

Patients who received EUS-GBD had a significantly shorter interval between gallbladder drainage and CCY, shorter surgical procedure times, and shorter length of stay for the CCY compared with those who received PT-GBD. EUS-GBD should be considered an acceptable modality for gallbladder drainage and should not preclude patients from eventual CCY.
Development of Specific Detection for Mungbean Yellow Mosaic India Virus Infecting Yard Long Bean in Java, Indonesia
Authors: Nurulita Sari , Mutaqin Kikin , Hidayat Sri
Published: May 2023

Yellow mosaic disease was reported for the first time in Indonesia in 2008. Its infection on yard long bean caused significant yield loss. Mungbean yellow mosaic India virus (MYMIV), member of genus Begomovirus was identified as the main causal agent. Specific and accurate detection is important for disease monitoring as part of disease management strategy. The aim of this study was to construct specific primer pairs for quick and robust detection of MYMIV using polymerase chain reaction method. A pair of primers MY1/MY2 was designed in this study to amplify part of MYMIV coat protein. In silico and in vitro test showed that MY1/MY2 primers specifically amplified MYMIV.
Review Artikel : Potensi Daun Pepaya (Carica papaya L.) sebagai Antikanker
Authors: Rahmawati Aisyah Muthiah , Anam Khairul , Sasikirana Widyandani
Published: May 2023

Pada tahun 2020, kanker menjadi penyebab kematian utama di dunia dan dalam kurung 5 tahun prevalensi kanker mengalami peningkatan di Indonesia. Kekurangan dari terapi kanker yaitu kurangnya selektif dalam mematikan sel kanker, sehingga dapat mematikan sel sehat maka dari itu pasien dapat merasakan efek samping yang cukup signifikan. Oleh karena itu, telah diteliti pencarian terapi alternatif dari daun pepaya. Tujuan dari artikel ini adalah mengetahui potensi daun pepaya sebagai antikanker. Artikel ilmiah yang dipublikasi 2010 – 2021 dari 2 database (Scopus dan PubMed) ditelaah dan didapatkan 38 artikel. Daun pepaya diketahui mengandung kandungan senyawa flavonoid, fenolat, steroid, alkaloid, terpenoid, fenolat, karotenoid, tannin, saponin, asam lemak, glikosida, glikosinalat, dan klorofil. Daun pepaya juga diketahui memiliki aktivitas antikanker terhadap kanker kulit, payudara, hepar, paru, pankreas, serviks, prostat, ovarium, mesothelioma, dan darah. Aktivitas antikanker daun pepaya dipengaruhi oleh karakteristik sel dan sampel uji. Pemilihan sel uji memengaruhi pengujian antiproliferasi, yaitu dengan doubling time yang singkat maka potensi antiproliferasi lebih tinggi. Kandungan senyawa pada daun pepaya memengaruhi aktivitas antikanker, dan perolehannya sangat berhubungan dengan pemilihan pelarut dan teknik ekstraksi yang tepat. Sistem penghantaran sampel dengan nanopartikel yang diformulasikan dengan daun pepaya juga membantu meningkatkan bioavaibilitas dari ekstrak daun pepaya, sehingga potensi antikanker meningkat.
Formulasi dan Evaluasi Fisik Sediaan Emulgel Ekstrak Daun Kelor (Moringa oleifera Lam.) sebagai Antioksidan dengan Gelling Agent HPMC
Authors: Puspitasari Fitri , Saraswati Indah , Wulandari Fitri
Published: May 2023

Radikal bebas dalam jumlah berlebih mengakibatkan stres oksidatif yang berdampak negatif bagi tubuh, maka dibutuhkan antioksidan untuk meminimalisirnya. Kelor mengandung 46 macam antioksidan dengan aktivitas sedang hingga kuat. Emulgel memiliki stabilitas dan akseptabilitas lebih baik dibanding sediaan topikal lainnya. HPMC digunakan sebagai gelling agent karena inert terhadap banyak bahan, mudah didapatkan, tidak toksik, dan tidak mengiritasi. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi HPMC sebagai gelling agent terhadap karakteristik dan stabilitas fisik emulgel ekstrak daun kelor, serta mengetahui aktivitas antioksidannya. Simplisia daun kelor dimaserasi dengan etanol 70%, lalu maserat dikentalkan dengan rotary evaporator. Kemudian, dilakukan penapisan fitokimia serta uji aktivitas antioksidan (IC50) dengan metode DPPH. Emulgel dibuat dengan memvariasikan konsentrasi HPMC (F1 = 3%, F2 = 5%, F3 = 7%), lalu dikarakterisasi fisik, uji stabilitas fisik dengan cycling test, serta uji aktivitas antioksidan (persen inhibisi) dengan metode DPPH. Hasil yang didapatkan yaitu konsentrasi HPMC berpengaruh terhadap karakteristik fisik emulgel. F2 dan F3 stabil secara fisik, sedangkan F1 hanya stabil pada daya lekat. Ekstrak daun kelor memiliki aktivitas antioksidan kuat (IC50 = 85,671±0,107 ppm). Persen inhibisi emulgel ekstrak daun kelor F1, F2, dan F3 berturut-turut sebesar 45,804±0,353%; 45,653±0,765%; dan 39,655±0,531%.
Analisis Tingkat Pengetahuan dan Dukungan Keluarga Pasien Hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung
Authors: Ramadhani Raihan , Dianingati Ragil Setia , Annisaa' Eva
Published: May 2023

Faktor risiko utama penyakit kardiovaskular adalah hipertensi. Keberhasilan pengobatan pada pasien hipertensi dipengaruhi oleh tingkat pengetahuan dan dukungan keluarga. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan dan dukungan keluarga pada pasien hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional. Sampel penelitian ini adalah pasien hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung pada Januari-Maret 2022. Metode pengambilan sampel yaitu purposive sampling. Pengumpulan data dilakukan menggunakan kuesioner pengetahuan dan dukungan keluarga. Uji statistik yang digunakan yaitu uji Chi-square. Hasilianalisis menunjukkan tingkat pengetahuan mayoritas sampel memiliki pengetahuan baik (36%) dan dukungan keluarga yang baik (36%). Tingkat pengetahuan dan dukungan keluarga pada pasien hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung tergolong baik.
Hubungan antara Efikasi Diri dengan Mobilisasi Dini pada Pasien Paska Bedah Mayor
Authors: Aisah Nur Aas , Ropyanto Chandra Bagus
Published: May 2023

Introduction: Self-efficacy affects the ability to perform early mobilization in patients after digestive surgery. The characteristics of pain are different in digestive and major surgical pain. Pain can effect self-efficacy and early mobilization.  The purpose of this study is to analyze the relationship between self-efficacy and early mobilization of major post-surgical patients.Methods: The study used a correlation descriptive design with a cross sectional approach with a total sample of 62 post operation patients aged 21-65 years who were compos mentis. The research instrument for self-efficacy used The General Self-Efficacy Scale (GSE), while early mobilization used Cumulated Ambulation Afternoon (CAS). Data were analyzed used Spearman rho.Results: The results showed that the mean self-efficacy score was 36,56 and the average value of early mobilization was 2.02. The results of correlation test obtained p value=0.172 with r=0.181.Conclusion: The conclusion of this study is that there was no significant relationship between self-efficacy with early mobilization. The suggestion in the study is to examine other factors that can affect early postoperative mosbilization. Keywords: Early Mobilization, Major Post-Surgical, Self-Efficacy.
Koping Positif Warga Binaan Pemasyarakatan dalam Menghadapi Stigma dan Diskriminasi
Authors: Nitsae Veronika , Andriany Megah , Mu’in Muhammad
Published: May 2023

Introduction: Stigma and discrimination are more common among women and affect the development of coping skills for women with HIV. Research related to coping strategies for prisoners with HIV in prisons is still very limited. This study aimed to identify the positive coping methods used and the reasons for using these coping strategies in dealing with stigma and discrimination against female inmates with HIV.Methods: This research method is a qualitative descriptive phenomenological design. The population of this study was female inmates living with HIV with a total of eight participants. Sampling was done by purposive sampling technique. Data was collected through in-depth interviews and analyzed using the Colaizzi technique.Results: The results of the study found two themes: (1) don't care and stay away from people who cause stigma to avoid problems; (2) attract sympathy and be honest with others to lighten the burden on the mind.Conclusion: Indifference certainly does not always have positive but also negative implications such as the emergence of disputes or divisions and individualism among prisoners. Meanwhile, active coping such as telling the truth can improve prisoners' physical and psychological well-being. The development of intervention programs such as narrative enhancement and cognitive therapy (NECT), family therapy, spiritual emotional freedom technique (SELF), and HIV peer support groups in prisons to develop active coping for female inmates with HIV in facing internal and public stigma is urgently needed. Keywords: Coping, Correctional Setting, Discrimination Stigma, HIV.
Pengaruh OTOF (One Team Student One Family) terhadap Pengetahuan Ibu dengan Balita Mencegah Stunting
Authors: Pamungkas Akhmad Yanuar Fahmi , Trianita Desi , Wilujeng Atik Pramesti
Published: May 2023

Introduction: The incidence of stunting is caused by several factors, one of which is the family factor. Mothers as the main caregivers for toddlers have a very important role in preventing stunting in children. Efforts to improve mothers' knowledge and skills in preventing stunting in toddlers continue to be carried out, but innovation is needed to increase mothers' understanding of the growth and development of toddlers so that stunting in toddlers can be prevented. One of the educational method innovations that can be carried out effectively is based on empowerment, namely 1 student 1 family, but there has been no research on a student team 1 family. The purpose of this study was to determine the effect of the OTOF (One Team Student One Family) on the level of knowledge among mothers of toddlers.Methods: This research was conducted in the working area of the Kertosari Public Health Center, Banyuwangi Regency from the beginning of June to the end of October using a pre and post-test quasy experiment with group control and using an independent t test. The population is all mothers who have toddlers. Sampling with stratified random sampling technique 61 respondents consisting of 31 interventions and 30 controls. The data collection instrument was Stunting Related Knowledge Questionnaire that has been declared valid and reliable the intervention used is to empower health students (nursing, analyst, midwifery, pharmacy and nutrition) according to their ability to carry out Health Education to 1 family. Results: The results showed that after giving the OTOF treatment the knowledge of the mother of toddlers increased and after being tested with the paired t-test, the result was p = 0.00 which means that there is an effect.  Conclusion: The conclusion is the results of the study show that there is an effect of the OTOF on the knowledge of mothers of children under five. Keywords: Mother Knowledge, OTOF, Stunting.
PERAMALAN JUMLAH PENUMPANG KERETA API DI PULAU JAWA MENGGUNAKAN METODE HOLT WINTERS EXPONENTIAL SMOOTHING DAN FUZZY TIME SERIES MARKOV CHAIN
Authors: Mendila Santa Agata , Utami Iut Tri , Kartikasari Puspita
Published: May 2023

One of the public transportation choices by the public is the train. The number of train passengers on the island of Java often increases and decreases in certain months. PT.KAI can monitor the number of train passengers by forecasting. Forecasting aims to predict the number of train passengers so that PT.KAI is ready to provide the best service. This study uses monthly data on the number of train passengers on Java Island from January 2015 to February 2020. This study uses multiplicative holt winters exponential smoothing and fuzzy time series markov chain. The multiplicative Holt Winters exponential smoothing method is used on data that contains trend and seasonal elements that experience data fluctuations simultaneously. The fuzzy time series markov chain method is a combination of the fuzzy time series with the markov chain which aims to obtain the greatest probability using the transition probability matrix. Based on the analysis results, it can be concluded that the multiplicative holt winters exponential smoothing method is better at predicting the number of train passengers on Java Island because the value of sMAPE multiplicative holt winters exponential smoothing is smaller, it is 3,0643% and the sMAPE fuzzy time series markov chain value is 5,2955%.
PENERAPAN METODE POISSON EXPONENTIALLY WEIGHTED MOVING AVERAGE (PEWMA) UNTUK MEMBUAT BAGAN PENGENDALI VARIABEL BERDISTRIBUSI POISSON
Authors: Adelia Nida , Mustafid Mustafid , Ispriyanti Dwi
Published: May 2023

Airplane is a mode of transportation that has an accident risk. Aircraft accidents are recorded to occur almost every year in Indonesia. The Poisson distribution is used to model the number of aircraft accidents that occur each year because they have a fixed time and independent. Statistical quality control is applied as a method to monitor the number of fatal aircraft accidents in Indonesia that are within control limits. One method to carry out quality control is to use a control chart. This study aims to apply the Poisson Exponentially Weighted Moving Average (PEWMA) method to create a control chart with a case study of the number of fatal airplane accidents in Indonesia from 1962 to 2021 with a Poisson distribution. The EWMA control chart is used to monitor the average or process variability and is considered effective in detecting small shifts in the process (the shift is said to be small if the shift is less than 1.5σ). The calculation of Average Run Length (ARL) is performed to test the performance of the PEWMA control chart. Control charts with smaller out-of-control ARLs are considered superior and can detect process shifts more quickly than other control charts. Based on the results of the calculation of the ARL value, it was found that the weight of 0.3 is the optimal weight with the smallest ARL value of 1.138 which is able to describe the state of the data on fatal aircraft accidents in Indonesia. The control chart with the optimal weight shows the data on fatal aircraft accidents in Indonesia that are tolerated equal to one.
The Effect of Marketing Mix on Patient Satisfaction and Their Impact on Patient Loyalty in Hospital Inpatients
Authors: Budiman Catherine , Achmadi Hendra
Published: May 2023

Hospital is a health-care institution that provides comprehensive individual health services through continuous service quality improvement and active marketing management. A marketing mix is a set of tools that can be controlled and used by hospitals to influence and create patient satisfaction so that patients become loyal. The marketing mix of the 4Ps (product, price, place, and promotion) can affect patient satisfaction and loyalty. The purpose of this study is to examine the relationship between the marketing mix and patient satisfaction, and its impact on patient loyalty. The type of research is quantitative research with hypothesis testing. This study obtained 165 respondents by filling out online questionnaires from this study and processed using PLS-SEM. The results indicated that the product, price, place, and promotion variables gave an R2 value of 0.519 for patient satisfaction as a mediating variable. The mediating variable successfully showed a positive effect on patient loyalty with R2 0.499 and mediated the impact of the independent variable. Product, price, place, and promotion significantly positively impact patient satisfaction, which then describes a significant positive effect on patient loyalty.
Pengaruh Internal Service Quality dan Workload terhadap Job Satisfaction Di RS Xyz Bojonegoro
Authors: Sutantio Arya Ganesha , Meilani Yohana F. Cahya Palupi
Published: May 2023

Introduction: One of the major factors in the success of a hospital is its employees, as a hospital contains many professionals that contribute greatly to the overall quality of service of the hospital. Thus, it is important for a hospital to maintain the Job Satisfaction of its employees, an employee that is motivated with their job would be more likely to be motivated and productive, resulting in better services given to the external customer of the hospital. Aim: This study was conducted to determine the effect of Internal Service Quality and Workload on Job Satisfaction. Methods: In this study, the data is collected using a questionnaire to 140 health workers in RS XYZ, Bojonegoro Regency using purposive sampling method. The analysis is done using partial lease square-structural equation modeling and carried out using SmartPLS software version 4.0. Results: The result of this finding is that both independent variables, Internal Service Quality and Workload have positive and negative correlation respectively. Conclusion: According to the result, providing a good Internal Service Quality to hospital employees would increase their job satisfaction, it is also important to manage workload appropriately as excessive workloads could lead to lower job satisfaction.
Hubungan Organizational Citizenship Behavior (OCB), Komitmen Organisasi, Kepuasaan Kerja terhadap Kinerja Perawat Rawat Inap di RSUD Dr. Adjidarmo Kabupaten Lebak
Authors: Mulya Dennison Laurensius , Meilani Yohana F. Cahya Palupi
Published: May 2023

One indicator of the success of the healthcare industry, especially hospitals, is the level of employee performance. One of the performances that plays an important role is the performance of nurse services to patients, nurses have an obligation to provide medical and non-medical services to patients. Good performance reflects the performance of a hospital, so performance is important to be optimized so that the hospital's success rate is optimal. Organizational Citizenship Behavior (OCB) is an important aspect that every nurse needs to have to support effectiveness at work, the level of commitment to the organization is an aspect that plays a role for every nurse in supporting the achievement of hospital goals, and a high level of job satisfaction makes nurses provide the best service. Research data will be collected through a physical questionnaire which will be given to 100 inpatient nurses at RSUD Dr. Adjidarmo Lebak district. Data analysis used the Smart PLS application version 4.0.7.8 and the partial least square equation analysis method. There is a positive and significant effect between OCB, organizational commitment, and job satisfaction on the performance of inpatient nurses at RSUD Dr. Adjidarmo Lebak disctrit.
Analisis Pengaruh Budaya Kesehatan, Kesadaran Kesehatan, dan Persepsi Produk Terhadap Konsumsi Jamu Pada Penderita Penyakit Pembuluh Darah di Bandar Lampung
Authors: Mumtazah Dzul Fithria , Saputra Iwan Eka , Setyaningrum Endah
Published: May 2023

Vascular disease is a condition that affects the arteries or veins. Vascular disease occurs when blood vessels are weakened, blocked, or damaged. Other organs and structures of the body may be damaged by vascular disease as a result of reduced blood flow to the organs. In Lampung, patients with heart and the vascular disease reached 13.000 people. Meanwhile, herbal medicine is an alternative medicine that is commonly consumed by people to reduce the severity of the disease they suffer, including vascular disease. This study was conducted to determine the effect of individual health culture, their health awareness, and their perception of herbal products consumption to relieve and treat vascular disease. This research is quantitative. Data collected in this study is based on a questionnaire that provides the thoughts of the respondents. The result shows that health culture and health awareness do not always affect the consumption of herbal medicines. But the perception they have affects their decision in consuming herbal medicines. The herbal medicine that is top of mind for patients with vascular disease in Bandar Lampung to relieve vascular disease is garlic. Steps a product marketer of herbal medicines for blood vessels and heart should take is a positive perception in various circles, in Indonesia, especially in Bandar Lampung.
Définir l’Afrique par la littérature – le littéraire comme vecteur de l’africanité dans le discours des Congrès des écrivains et artistes noirs (Paris, 1956 et Rome, 1959)
Authors: Obszyński Michał
Published: May 2023

In our paper we show how Black writers (those of Africa and those of the Black diaspora in Europe and America) have contributed to the intellectual work centered on the idea of Africanity. We explain to what extent literature, as one of the domains of culture, reflects different visions of Africa, as formulated in the discourse of the World Congresses of Black Writers and Artists (Paris, 1956 and Rome, 1959). With reference to the official texts presented or elaborated during these events, we expose in which way literature is involved in the decolonial remapping of the geocultural place of Africa and in the remodeling of the postcolonial literary geography while pointing out the precursory or heralding character of certain postulates whose echoes will be heard during the festivals of negro and pan-African art of the 1960s and whose relevance is also confirmed nowadays.
L’espace concentrationnaire et la figure du « musulman » dans Les Boucs de Driss Chraïbi
Authors: Pawlicki Jędrzej
Published: May 2023

The article examines the question of the concentration camp space and the figure of the “Muslim” in the novel Les Boucs (1955) by the Moroccan writer Driss Chraïbi. Published ten years after the war, the novel nevertheless uses certain motifs from the literature of the camps. Even if the geography of “Arab Paris” in North African literature has been well described and analyzed, the kinship of the Goats with concentration camp literature has not received sufficient attention. Therefore, in my study I will first recall the circumstances of publication of the novel and the main lines of its reception by critics to then move on to the analysis of the concentrationary space in the novel. The link with the space of the camps will finally be reinforced by the evocation of the figure of the “Muslim”, well known from the testimonies and expressly exploited by Driss Chraïbi.
Exploration of suitable external quality assessment materials for serum C-peptide measurement
Authors: Deng Yuhang , Zhang Chao , Li Bingqiong , Wang Jing , Zeng Jie , Zhang Jiangtao , Zhang Tianjiao , Zhao Haijian , Zhou Weiyan , Zhang Chuanbao
Published: May 2023

Objectives

To find suitable external quality assessment (EQA) materials for serum C-peptide, we evaluated the commutability of five types of processed materials.

Methods

Seventy-four individual serum samples and 12 processed samples including three EQA samples currently in use, frozen human serum pools (FHSP), and three other kinds of processed samples were prepared by dissolving WHO International Standard Reagent for C-peptide (WHO ISR 13/146) in three different matrixes: 0.05 % bovine serum albumin, fetal bovine serum and human serum pools. Samples were analyzed using the isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS) method and six widely used immunoassays. The commutabilities of processed materials were assessed according to the difference in bias approach recommended by the IFCC. And the short- and long-term stability of FHSP samples at different temperatures were also evaluated.

Results

Out of the five kinds of processed materials, FHSP samples were commutable on most assays. In contrast, the EQA materials currently in use were only commutable on a few immunoassays. Additionally, processed materials derived from WHO ISR 13/146 were found to be un-commutable on over half of immunoassays. The FHSP samples could be stably stored at 4 and −20 °C for at least 16 days, and at −80 °C for at least 1 year, but at room temperature only for 12 h.

Conclusions

With clarified commutability and stability information, the human serum pool samples along with the developed ID-LC-MS/MS method could be used in the EQA program to promote the comparability among laboratories for C-peptide measurement in China.
Prenatal diagnosis of non-mosaic sex chromosome abnormalities: a 10-year experience from a tertiary referral center
Authors: Wu Xiaoqing , Guo Danhua , Li Ying , Xie Xiaorui , Su Linjuan , Cai Meiying , Zheng Lin , Lin Na , Liang Bin , Huang Hailong , Xu Liangpu
Published: May 2023

Objectives

The aim of this study was to explore the frequency and profile of non-mosaic sex chromosome abnormalities detected in prenatal diagnosis over the past 10 years.

Methods

We retrospectively reviewed pregnancies diagnosed with non-mosaic sex chromosome abnormalities between January 2012 and December 2021, using karyotyping and/or single nucleotide polymorphism (SNP) array. Maternal age, indications for testing, and outcomes were recorded.

Results

Traditional karyotyping identified 269 (0.90 %) cases of non-mosaic sex chromosome abnormalities among 29,832 fetuses, including 249 cases of numerical abnormalities, 15 unbalanced structural abnormalities, and 5 balanced structural abnormalities. The overall detection rate of common sex chromosome aneuploidies (SCAs) was 0.81 %, with 47,XXY, 47,XXX, 47,XYY, and 45,X accounting for 0.32 , 0.19, 0.17, and 0.13 % respectively. All showed a fluctuating upward trend over the study period, except for 45,X. During the first five years (2012–2016), the major indication for testing was advanced maternal age (AMA), followed by abnormal ultrasound, abnormal noninvasive prenatal testing (NIPT), and abnormal maternal serum screening (MSS). In the second five years (2017–2021), the most frequent indication was abnormal NIPT, followed by AMA, abnormal ultrasound, and abnormal MSS. Among the 7,780 cases that underwent SNP array in parallel, an additional 29 clinically significant aberrations were detected. The most frequent aberration was a microdeletion in the Xp22.31 region, which was associated with X-linked ichthyosis.

Conclusions

Fetal sex chromosome abnormalities are important findings in prenatal diagnosis. The application of NIPT and SNP array technology has greatly improved the detection of SCAs and submicroscopic aberrations associated with sex chromosomes.
Crystal structure of trans-N
1,N
8-bis(2-cyanoethyl)-5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane, C22H42N6
Authors: Rabi Saswata , Dey Lucky , Rahman Ismail M. M. , Tiekink Edward R. T. , Roy Tapashi Ghosh
Published: May 2023

C22H42N6, triclinic, P

1
‾

$\overline{1}$

(no. 2), a = 8.3115(2) Å, b = 8.8263(2) Å, c = 9.7688(2) Å, α = 

111.490

(
2
)

°

$111.490(2){}^{\circ}$

, β = 

115.056

(
2
)

°

$115.056(2){}^{\circ}$

, γ = 

93.681

(
2
)

°

$93.681(2){}^{\circ}$

, V = 583.25(3) Å3, Z = 1, R

gt
(F) = 0.0465, wR

ref
(F
2) = 0.1351, T = 294 K.
Driver's seat: A qualitative study of transformational student partnerships in SoTL
Authors: Shank Makayla , Cruz Laura
Published: May 2023

This qualitative study is based on a series of interviews conducted with students (n=6) who participated in the inaugural cohort of a year-long students-as-partners program called CTL Scholars. As one of the first students-as-partners programs implemented at this large, dispersed, public research institution, students of diverse majors and research perceptions identified three common themes from their participation: motivation, agency, and partnerships. Our findings suggest that students-as-partners programs such as CTL Scholars can establish students as agents of their own learning, promote equitable relationships between students and faculty members, and potentially contribute to both teaching transformation and research productivity.
Human-body Analogy Improves Mental Rotation Performance in People Aged 86 to 97 Years
Authors: Muto Hiroyuki , Gondo Yasuyuki , Inagaki Hiroki , Masui Yukie , Nakagawa Takeshi , Ogawa Madoka , Onoguchi Wataru , Ishioka Yoshiko , Numata Keitaro , Yasumoto Saori
Published: May 2023

Mental rotation is a spatial ability allowing one to represent and rotate an object in one’s mind, and its performance declines with age. Given previous findings indicating that likening a to-be-rotated object to a human body improves mental rotation performance in young adults, we examined whether this human-body analogy would improve older adults’ mental rotation performance. We also tested whether the human-body analogy effect is age-dependent. In the present study, we analyzed data from 423 community-dwelling older adults (age range: 86–97 years; 219 men and 204 women) who answered two items of a paper-and-pencil mental rotation test: one on abstract cube objects (control condition) and one on cube objects with a human face (embodied condition). The results revealed that more participants correctly answered the item in the embodied condition (32.2%) compared to that in the control condition (19.6%), indicating that the human-body analogy is effective in an oldest-old population (i.e., people aged over 85 years). Notably, we found age differences in human-body analogy effects. While accuracy for mental rotation of abstract objects declined with age, accuracy for embodied objects was preserved with age. These findings suggest that the human-body analogy may prompt older adults to adopt a holistic, rather than a piecemeal, rotation strategy.
Gait recognition methods in the task of biometric human identification
Authors: Purish Sergiy V. , Lobachev Mykhaylo V.
Published: May 2023

This article focuses on defining the problem of solving the problem of human identification by means of gait recognition in bi-ometric identification systems.In order to determine the prospects of using gait recognition methods for human identification, a gen-eralized model of a biometric identification system was considered, the main modules of the system were identified and a brief de-scription of each module was provided.Next, the basic requirements for human biometric features were identified, the main bio-metric features were considered, and the features of their use in biometric identification systems were determined.The issue of using gait as a biometric identifier was also considered. It has been determined that the use of human gait allows to get rid of two main obstacles in the construction of biometric identification systems: users are not required to provide personal biometric information in advance, and the system does not require specialized equipment.Also, the issue of multi-view gait recognition was considered. Mul-ti-view gait recognition involves capturing gait data from different angles and using this data to improve recognition accuracy.This approach has shown great promise in challenging scenarios such as low lighting conditions.Next, we analyzed scientific works in the field of gait recognition. It was determined that gait recognition methods can be divided into template-based and non-template-based methods.Template-based methods are aimed at obtaining patterns of torso or leg movements, i.e. they usually focus on the dynamics of movement in space or on spatio-temporal methods. Non-template-based methods consider shape and its features as more relevant characteristics, i.e., human recognition areperformed using measurements that reflect the shape of the person.Next, we consider the use of different datasets in the process of training and testing human gait recognition methods. The main datasets were identified and their characteristics and features were collected.We considered the presence of various characteristics in the datasets, as well as the means of representing information about human gait.The researchhas identified the main problems and challenges facing research-ers in this area, as well as the main trends in the field of human gait recognition in biometric identification systems.
DEPREMDEN HASAR GÖREN BİNALARIN SEBEP OLDUĞU ZARARLARDAN KAYNAKLANAN HUKUKÎ SORUMLULUĞA GENEL BAKIŞ – II – HAKSIZ FİİL SORUMLULUĞU
Authors: AKKURT Sinan Sami
Published: May 2023

Bu çalışma, 6 Şubat 2023'te meydana gelen ve Mart 2023 sonu itibariyle açıkla-nan resmî rakamlara göre Türkiye'de yaklaşık “kırksekiz bin” kişinin hayatını kaybetmesine yol açan Gaziantep ve Kahramanmaraş depremlerinden kaynak-lanan zararlardan muzdarip kişilerin ve bu kişilere hukukî çare aramakta olan çok sayıda hukukçunun hukuksal arayışlarına genel hatlarıyla ve fakat ivedilikle bir rehber oluşturmak amacıyla yapılan araştırmanın, haksız fiil sorumluluğuna ilişkin ikinci kısmıdır.

Sorumlular ve sorumluluk, genel olarak zarar görenlerle sorumluluk süjeleri arasındaki hukukî ilişkilere göre belirlendiği ve şekillendiği için, iki kısımdan oluşan çalışmanın bu ikinci kısmında deprem zararlarından kaynaklanan hak-sız fiil sorumluluğu üzerinde durulmuştur. Çalışmanın sözleşme sorumluluğu-na ilişkin ilk kısmı ise “Depremden Hasar Gören Binaların Sebep Olduğu Zararlardan Kaynaklanan Hukukî Sorumluluğa Genel Bakış – I – Sözleşme Sorumluluğu” adı altın-da ayrı bir makale olarak hazırlanmıştır
First record of Mysidopsis gemina Price, Heard & Vargas, 2019 (Crustacea, Peracarida, Mysida, Mysidae) on the west coast of Mexico
Authors: Hernández-Payán José Carlos , Hendrickx Michel E.
Published: May 2023

Mysidopsis gemina Price, Heard & Vargas, 2019, a species of mysid shrimp recorded for Pacific Costa Rica, was collected in western Mexico on October 19th, 2022, at the entrance of the Gulf of California. This is the first record north of Costa Rica and it represents a distribution range extension to the north of approximately 13 degrees of latitude. A comparison of the diagnostic morphological features of the Costa Rican and Mexican specimens is given.
Sobre la necesidad de una nueva base nihilista para el pensamiento filosófico
Authors: Morales C.
Published: May 2023

El desarrollo de la tradición filosófica, ocupada en la pregunta por el conocimiento, ha demostrado los límites de un modo de pensar que, aunque limitado en su alcance, ha querido identificarse con la esencia del pensar. Frente a esto es necesario reivindicar un pensamiento que no tenga miedo de pensarse a sí mismo como labor destructiva y como reivindicación de todo lo que se ha considerado hasta ahora como nihilismo.
La justicia como pretensión política. John Locke entre el Medioevo y la Modernidad
Authors: Fernández Peychaux D.A.
Published: May 2023

En este artículo se busca situar el pensamiento de Locke entre dos momentos históricos bien diferentes, pero profundamente relacionados. El concepto que servirá como bisagra a esta investigación en dicho propósito es el de «justicia». Así, se indagará no solo qué se entiende por justicia, sino también la posición otorgada a esta por el autor inglés en su teoría. En particular, en referencia a las relaciones de poder de la sociedad. De este modo, se cree poder demostrar que el contrato social de Locke tiene por función rehabilitar un espacio libre de dichas relaciones injustas de poder político y económico.
El realismo del texto en los estudios sociales de la ciencia
Authors: Rioja Nieto Ana
Published: May 2023

Tras la relativización de la ciencia llevada a cabo por la sociología del conocimiento científico, la exigencia de evitar la auto-refutación ha conducido a algunos autores a extender este programa de relativización del conocimiento a la propia sociología del conocimiento, lo cual supone omitir en la escritura todo tipo de práctica representacional de carácter realista. Este artículo se propone analizar críticamente el alcance y la viabilidad de esta empresa en el marco de los estudios sociales de la ciencia.
Kurt Gödel: el límite lógico de la Modernidad
Authors: Rodriguez Peña A.
Published: May 2023

El proyecto formalista ideado por Hilbert es deudor de un filósofo que podemos considerar como el padre fundador de la modernidad: Descartes. En este escrito se buscará interpretar el teorema de limitación de Kurt Gödel, que muestra la imposibilidad de dicho proyecto, como una crítica a la modernidad.
Algunas consideraciones sobre la relación entre epistemología y psicología en Thomas Kuhn
Authors: Brunetti J.
Published: May 2023

La epistemología de Kuhn puede abordarse desde distintos puntos de vista. En este caso el centro está puesto en la relación que guarda con la psicología del conocimiento. Las etapas de maduración que atraviesa su pensamiento están marcadas por una forma particular de entender el conocimiento y que Kuhn pretende explicar desde distintas teorías psicológicas. El tema permite pensar algunas dificultades previas respecto de cómo Kuhn elabora la relación entre psicología y epistemología.
Auto-creación de Dios y desfundamentación del mundo
Authors: Rocco Lozano V.
Published: May 2023

El propósito del presente artículo es el de mostrar las dificultades que plantea la concepción de Dios como fundamentum inconcussum realitatis, dado que los predicados de la necesidad divina y el papel de Dios como creador pueden entrar en conflicto entre sí y con otros atributos clásicos del teísmo como la omnibenevolencia y la omnipotencia. A pesar de que se suele considerar imprescindibles, como atributos de Dios, su ser necesario fundamento de todo lo contingente y a la vez creador increado del mundo, habrá que admitir la posibilidad, por lo menos teórica, de un Dios creado y contingente, lo que abre grandes interrogantes y problemas, como el del suicidio de Dios, tema tratado por Richard Swinburne, así como otras cuestiones como la posibilidad de un Dios-regente.
Dios como fundamento: la tópica trascendental
Authors: Jiménez Rodriguez A.
Published: May 2023

El presente artículo trata de pensar el concepto de Dios en su respecto lógico (entendida aquí la lógica como ciencia de la verdad) estudiando el sentido de las subrepciones en el marco de la anfibología de los conceptos de reflexión de la primera Crítica kantiana. La operación de sustitución del lugar de Dios como fundamento de lo real por un Dios postulado permite poner en conexión esta cuestión con el  problema más general de los límites del conocimiento.
El hechizo platónico
Authors: Álvarez R.
Published: May 2023

Este artículo revisa algunas diferencias que Platón va abriendo dialécticamente, desde el interior, en la apreciación de la maldad, la mentira y el discurso, y de modo paulatino, a lo largo de sucesivas obras. El objeto sería desbaratar dicotomías equívocas así como poner los moldes filosóficos del mito y la imitación artística que producen los propios diálogos. Como resultado del hechizo platónico, la filosofía desplaza los métodos arcaicos de educación entre las élites griega se instaura un modelo trágico, mítico y de discurso operativo todavía en el presente.
Arte y mundo hoy: Acerca de la vigencia de la meditación heideggeriana sobre la obra de arte
Authors: Galvín Redondo P.
Published: May 2023

La interpretación del arte de Heidegger destaca por su radicalidad y originalidad. Para el pensador alemán, la esencia del arte se mantendrá oculta mientras no se ponga en conexión dicha actividad productiva con la pregunta por el ser. Al proceder así, se nos revela, por un lado, la constitutiva dimensión ontológica del arte y su íntima vinculación con el fenómeno de la verdad y, por otro, la insuficiencia de los tradicionales planteamientos sobre el arte y de la estética como disciplina filosófica. ¿Continúa vigente dicho planteamiento ontológico?, ¿es compatible con las nuevas condiciones de la producción artística emergentes en el actual mundo científico-técnico?
El arte 2.0 como estética invisible
Authors: Rouyet Ruiz J.I. , Joyanes Aguilar L.
Published: May 2023

Actualmente todo aquello que quiere ser novedoso tiene el apelativo de “2.0”, como ocurre con el denominado Arte 2.0, que bebe de las fuentes de la Web 2.0. Pero esta novedad se queda en copia si tan solo consiste en cambiar el lienzo por la tecnología, y el artista por el espectador. La principal característica de la Web 2.0, la que la distingue de la Internet de hace una década, es lo que se denomina ‘sombra de información’. Nuestra propuesta consiste en reclamar al arte la capacidad expresiva de representar dicha ‘sombra de información’, creando así un verdadero Arte 2.0. El Arte 2.0 debe ser la estética de esa ‘sombra de información’ y constituirse en la estética de lo invisible.
Cyborgs en la acción pedagógica: Una reflexión a partir de un discurso de Donna Haraway
Authors: Ramírez Pavelic M.
Published: May 2023

Este ensayo intenta reflexionar sobre la acción pedagógica construida a partir del libro “Ciencia, Cyborgs y mujeres, la reinvención de la naturaleza” de Donna Haraway. Desde la definición de Cyborg como un monstruo cibernético, constituido por máquina y organismo, irónico, perverso y astuto, pero a la vez responsable y pacifista, intentaremos dibujarun panorama donde la ciencia ficción se mezcla con la realidad en el ámbito educativo. En este contexto, no podía quedar fuera una mirada a la tecnología de la dominación y a las metodologías obsoletas que se aprecian aún en algunas instituciones escolares.
Samuel Ramos y el nuevo humanismo
Authors: Lizaola J.
Published: May 2023

Las preocupaciones culturales y educativas de Samuel Ramos están íntimamente relacionadas con una propuesta filosófica más amplia. En ella contempla, fundamentalmente, la necesidad de realizar una antropología filosófica que nos aproxime a la indispensable reflexión sobre el hombre contemporáneo y especialmente sobre el mexicano. ¿Qué idea de hombre existe, fundamenta, sostiene, el actuar en específico del mexicano? Su respuesta se dirige a considerar que el alma del pueblo mexicano posee, por sobre cualquier otra distinción, el rostro del sufrimiento y la humillación, los cuales generan un sentimiento de inferioridad fortalecido por la larga serie de procesos dolorosos y traumáticos que han conformado su proceso histórico. Esta interpretación del mexicano como un ser paralizado e impotente, le permite elaborar su propuesta de una antropología filosófica cercana a la sugerida por Max Scheler que parte de una pregunta decisiva: ¿cuál es el puesto del hombre en el cosmos? O dicho más propiamente: ¿cuál es el puesto del mexicano como ciudadano de una sociedad moderna? Su respuesta implica la necesidad de elaborar un sentido, una direccionalidad e intencionalidad que Ramos denomina Nuevo Humanismo. Este es el punto central, el identificar la estructura que sostendrá a este nuevo hombre consciente, a y la vez perdido, en el mundo contemporáneo.
Memoria y escritura en Rosa Chacel
Authors: Trapanese E.
Published: May 2023

Este ensayo ofrece un breve análisis que, a partir de la obra de la autora española Rosa Chacel, intenta centrarse en las relaciones filosófico-literarias existentes entre memoria y escritura. Desde esta perspectiva, se propone un estudio de las diferencias y de las convergencias entre “autobiografía” y “confesión”, en cuanto géneros literarios en los que la escritura se hace memoria, recuerdo, en sus múltiples facetas.
La universalidad racional de los derechos
Authors: Hermida del Llano Cristina
Published: May 2023

Los derechos humanos representan un mínimo ético universal que permite calificarlos como derechos morales. Sus rasgos son la racionalidad y la abstracción, congruentes con la titularidad que ostentan todos los seres humanos. Los derechos fundamentales encierran siempre valores o bienes que se han considerado lo suficientemente relevantes como para ser dignos de protección por un determinado sistema normativo y representan en nuestros días el corazón de las identidades constitucionales. Por ello están garantizados judicialmente. Una gran amenaza para la universalidad de los derechos es el relativismo cultural y el nacionalismo pues olvidan la idea de la unidad de la condición humana y de una universalidad humanista sobre los fines morales del hombre.
Where philosophy and the ideas of democracy and human rights meet: the complex "equation" of the Swiss political system and its international relevance
Authors: Gonin Luc
Published: May 2023

This article aims to demonstrate the important links that exist between democracy, human rights and philosophy. It presents the Swiss political system, which is constantly subjected to a tension between the respect of human rights and the respect of democracy, due to its semi-direct system of democracy. This article also highlights clearly the international relevance of the Swiss problem. Moreover, this contribution shows how much the question analysed is rooted in Western political philosophy and is, therefore, not ‘purely’ legal.
La democracia cansada. Globalización, postmodernidad y multiculturalismo
Authors: Caro Rey Jonatan
Published: May 2023

Este artículo se propone pensar nuestra “condición democrática” desde dos claves principales: la globalización y la postmodernidad. El panorama que de ese análisis se desprende es negativo en relación a la valoración de la democracia. Desde el punto de vista de la filosofía es preciso aportar una fundamentación que anime y contribuya a un cambio de rumbo: es preciso apreciar las potencialidades de nuestra democracia allí donde sólo vemos problemas: en la diferencia, en el escepticismo, en la incredulidad.
La propuesta de Krause de una Federación Europea de Estados (1814) a la luz de su concepción universal del derecho
Authors: Pinilla Burgos Ricardo
Published: May 2023

Se presenta la propuesta de Krause sobre una Federación de los Estados Europeos con ocasión del Congreso de Viena (1814). Este proyecto contiene elementos de gran valor aun hoy día para concebir la unión europea y sentar las bases de un derecho internacional entre los Estados, y obedece y es fruto de una concepción determinada del derecho que se expone en el artículo, tanto en su evolución como en sus importantes raíces metafísicas que hacen de la idea de derecho un componente fundamental de la relación de los seres entre sí y con el principio absoluto de todo lo real. El artículo perfila desde ahí el talante del europeísmo y cosmopolitismo en Krause como una de las señas de identidad esenciales del krausismo.