bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhancing Seventh-Grade Numeracy Skills in Data Presentation Through Interactive Gaming
Authors: Juwiantho Hans , Sidarta Alycia Jane
Published: December 2024

Integrating educational content into a game format aims to make learning more enjoyable and accessible to students. The game’s design focuses on gradually increasing the difficulty level to challenge students’ abilities and encourage problem-solving. The benefit of this numeracy game for learning is its ability to create a lively and interactive learning environment. By immersing students in a captivating storyline and providing opportunities for exploration and discovery, the game fosters engagement and enthusiasm for learning. The game offers immediate feedback to players, allowing them to learn from their mistakes and improve their skills over time. Moreover, the game is a supplementary tool for educators to reinforce classroom learning and provide additional practice opportunities for students. It encourages independent learning and critical thinking while reinforcing mathematical concepts in a fun and interactive way. Survey results consist of 21 seventh-grade students from various schools, indicating high engagement, with 95.2% finding the game stimulating. The pre-test and post-test have 5 questions covering various mathematical concepts relevant to numeracy skills; the questions addressed topics such as pie charts, graphs, tables, logical reasoning, and drawing conclusions from given data. The result scores show improvement, rising from 2/5 to 3.43/5, suggesting a learning process during gameplay.
Digital Literacy, Pedagogical Insight, and Self-Belief: An Exploration of Pre-Service Teacher Z-Generation
Authors: Jaya Fitra
Published: December 2024

Generation Z currently dominates the student population in pre-service teacher education programs. Analyzing the differences in characteristics between Generation Z pre-service teachers and those from previous generations is crucial. In the ever-evolving digital era, Generation Z pre-service teachers need to possess strong digital literacy, deep pedagogical understanding, and adequate self-confidence to meet the demands of the digital age. This study aims to investigate the role of digital literacy and self-efficacy among pre-service teachers as mediators in their relationship with technological pedagogical content knowledge (TPACK). This research is quantitative in nature. Data were collected from 105 Generation Z pre-service teachers from various study programs across two different provinces in Indonesia. The instruments used to measure the variables included questionnaires on digital literacy, self-efficacy, and TPACK. The Structural Equation Model (SEM) was employed to analyze the structural relationships. The findings reveal that Generation Z pre-service teachers have a strong inclination towards digital literacy, which influences their pedagogical insights in implementing technology in teaching and learning processes. The development of pre-service teacher training programs is necessary to adapt to the needs of Generation Z and the rapid technological advancements in the future. A solid grasp of digital literacy and pedagogical insights can effectively prepare qualified educators
Positive Dicipline Parenitng: Mathematics Learning Strategies for Elementary School Students Self-Confidence
Authors: Ibrahim Malik , Fauziah Puji Yanti , Riana Riana , Muzdybayeva Guldana
Published: December 2024

Mathematics is still a challenge for students in learning both at school and at home. Children tend to feel insecure when learning mathematics. This research aims to determine the effect of positive disciplinary parenting in mathematics learning on elementary school students' self-confidence. The research method uses quantitative research with an ex post facto design, where research data on learning outcomes uses semester grades in mathematics subjects. The research sample was 30 students from 3 schools taken randomly with taken using a quota sampling technique from each school was determined to have 10 students. Data collection uses learning outcomes tests and student self-confidence questionnaires. The results of the research show a sig value > 0.031 and an F value of 11,774, which means that there is a significant relationship between positive discipline parenting and students' self-confidence in elementary school students' mathematics learning. Apart from that, the results of the student self-confidence questionnaire were in the very high category at 90% and in the high category at 85%, meaning that elementary school students have an average of high self-confidence in learning mathematics with positive disciplinary parenting. Thus, the results of this research need to be taken into consideration by parents and educational institutions collaborating in assisting students to develop self-confidence in learning.
Development of Honesty Attitude Assessment Instruments for Junior and Senior High School Students
Authors: Sinta Dewi , Rahmat Munawar , Anwar Saepul
Published: December 2024

The preparation of honesty attitude assessment instruments is essential for planning to improve student honesty. Assessment and improvement of student honesty in the educational environment are critical to forming a strong character of integrity. This study aims to develop an honesty attitude assessment instrument for junior high and high school students. This study uses a development research method with a theory development model. The instrument's development was first conducted through a theoretical study with a literature study to formulate indicators. Then, the researcher created an instrument based on these indicators, consulted with the supervising lecturer, asked for expert judgment, conducted validity and reliability tests, and conducted analysis. The study results showed four indicators of honesty: honesty, trustworthiness, keeping promises, and fairness. The instrument developed was in the form of 40 questionnaire items using a Likert scale. This instrument was tested on 103 grade 9 students at SMP Laboratorium Percontohan UPI. The analysis showed that the instrument was valid and reliable, with an alpha coefficient of 0.8723. The practical implications of this study indicate that this instrument can be used in quasi-experimental research. Theoretically, this study can enrich the theory of measuring honesty attitudes and be the basis for further research.
IRE Teachers' Efforts to Improve Digital Literacy to Strengthen Religious Interaction towards a Good Digital Citizenship Society
Authors: Hyangsewu Pandu , Abdullah Hilman Taufiq , Faqihuddin Achmad , Muflih Abdullah
Published: December 2024

Digital literacy, including Islamic Religious Education (IRE), has become essential in modern education. This article discusses the efforts of IRE teachers in improving digital literacy to strengthen students' religious interactions toward forming a Good Digital Citizenship society. This study uses a qualitative approach to explore the experiences and strategies of IRE teachers in Junior High Schools (JHS) and Senior High Schools (SHS) in integrating technology into learning. Data were obtained through in-depth interviews with 10 IRE teachers skilled in digital literacy and accustomed to using digital media and content in teaching. The data were analyzed using the Miles and Huberman framework, involving data reduction, data display, and conclusion drawing to identify patterns and themes related to digital literacy integration. The study results show that IRE teachers integrate technology through digital tools such as Google For Education, Quizizz, Canva, and video platforms such as YouTube to enrich the learning experience. Teachers also create digital content such as interactive modules, educational videos, and podcasts, which engage students and expand access to relevant religious information. Additionally, teachers provide digital literacy education that includes training on digital ethics, online security, and responsible social media usage. This study concludes that digital literacy in IRE supports students' technological skills and helps shape their moral character in the digital world. This effort significantly contributes to forming students as good digital citizens who can interact ethically and productively in the digital space. The implications of this study indicate the importance of ongoing digital literacy training for teachers and students to support relevant religious education in the digital era.
Determinant Factors Influencing Teacher Performance in the Digital Era
Authors: Nadifa Milatun , Mustiningsih Mustiningsih , Sumarsono Raden Bambang
Published: December 2024

This study aims to examine the factors influencing teacher performance in the digital age, focusing on both supportive and obstructive elements shaping their effectiveness in integrating digital tools into teaching practices. The research systematically examines how technological and pedagogical factors, personal factors, organizational support, contextual factors, technostress, and the digital divide impact teacher performance. A systematic literature review was conducted using PRISMA guidelines, analyzing 650 scholarly articles published between 2020 and 2024. Articles were sourced through the Publish or Perish (PoP) application, applying specific inclusion criteria, such as empirical studies published in accredited journals and relevance to the study objectives, while excluding articles that lacked methodological rigor or were not written in English or Indonesian. From this process, 94 high-quality articles were selected for analysis. Data were processed using a scoring matrix to assess article quality and relevance, and findings were systematically categorized using Microsoft Excel to generate narratives, tables, and diagrams. The results reveal six critical factors affecting teacher performance: technological and pedagogical competence, personal factors, organizational support, contextual factors, technostress, and the digital divide. These findings highlight the complexity of teacher performance in the digital age and underscore the necessity of institutional support, continuous professional development, and policies to address technology-related disparities and stress. This study provides valuable insights for designing evidence-based strategies to enhance teacher effectiveness and educational quality in the era of digital transformation.
Development of Novel Ketoconazole Emulgel Formulations for Enhancing Penetration
Authors: Deshmukh Susheel , Ganju Eisha , Gupta Bhaskar Kumar
Published: December 2024

Aim: This study aimed to develop and evaluate a novel emulgel formulation of ketoconazole to overcome its poor solubility and limited skin permeability, thereby enhancing its topical delivery and antifungal efficacy. Methodology: Ketoconazole was incorporated into an oil-in-water emulsion, which was then combined with a suitable gelling agent to form the emulgel. Various oils, emulsifiers, and gelling agents were optimized to achieve better drug release and skin permeation. The formulations were evaluated for physical appearance, pH, spreadability, viscosity, and drug content uniformity. In vitro skin permeation studies were conducted using excised rat skin to compare the permeation profile of the emulgel with a conventional ketoconazole cream. Ex vivo antifungal efficacy was assessed against Candida albicans to determine the therapeutic potential of the emulgel. Results: The optimized ketoconazole emulgel exhibited ideal physicochemical properties, including an appropriate pH, superior spreadability, and viscosity suitable for topical application. In vitro permeation studies revealed a 3-fold increase in skin penetration compared to the conventional cream. Ex vivo antifungal studies demonstrated enhanced antifungal activity, with the emulgel showing significantly higher efficacy against Candida albicans than the conventional cream. Conclusion: The development of a ketoconazole emulgel offers a promising strategy for improved topical delivery and antifungal efficacy. By enhancing skin penetration and providing sustained drug release, this emulgel system addresses the limitations of traditional formulations. Further clinical studies are recommended to explore its potential for treating superficial fungal infections.
V957 Cep is a Zero-Age Eclipsing System
Authors: Volkov I. M. , Naroenkov S. A. , Kravtsova A. S.
Published: December 2024

New high-precision photometric measurements of the V957 Cep system (P = 1.99d, V = 11.17m, e = 0.127, B6 V+B8 V), as well as an integrated approach to orbital parameters determining based both on photometric solutions of the light curves and on the study of the course of residual deviations of the minima timings from the linear formula O – C made it possible for the first time to accurately measure the apsidal motion rate: ω˙obs= 2.91°/year, which coincided with the theoretical value under the condition of the orbital and axial rotations synchronism:ω˙theor = 2.92°/year. The physical parameters of the component stars were obtained: T1 = 14550 ± 300 K, M1 = 4.0 ± 0.2 M•, R1 = 2.55 ± 0.05 R•, T2 = 12400 ± 250 K, M2 = 3.0 ± 0.15 M•, R2 = 1.88 ± 0.05 R•. This set of parameters corresponds to stars of zero age, recently descended to ZAMS. The secondary component is a pulsating variable star of the β Cephei type.
Metallicity and Kinematics of the Circumsolar Stellar Population of the Galaxy
Authors: Tutukov A. V. , Chupina N. V. , Vereshchagin S. V.
Published: December 2024

The study of the kinematics and genetics of stellar populations in the Galaxy continued within a sphere with a radius of 300 parsecs based on the Gaia catalog (AG300). The main attention is paid to the chemical composition and genetics of stars in the corona of the core (halo) of the Galaxy with highly elliptical orbits and stars with hyperbolic orbits from the vicinity of the Sun. The possible role of various mechanisms of acceleration of the spatial motion of stars in the formation of the stellar corona (halo) of the Galaxy and stars with high hyperbolic (v 500 km/s) velocities in the vicinity of the Sun is considered. Supernova explosions in close binaries and the disintegration of unstable close triple stars have been proposed as possible mechanisms for the acceleration of these stars. The abundance of iron in corona stars coincides with the abundance of iron in globular clusters, which is an argument in favor of their relationship. It is shown that about 7% of low metallicity stars ([Fe/H] 3), judging by the position of their apexes, may belong to the “first” stars of the Galaxy, or they are products of the decay of low-mass satellites of the Galaxy.
Structural Connection of the Chukchi Borderland and the Chukchi Sea Shelf: 3D Geophysical Modelling of the Earth Crust
Authors: Piskarev A. L. , Kireev A. A. , Ovanesyan G. I. , Poselov V. A. , Savin V. A. , Smirnov O. E. , Tabyrtsa S. N.
Published: December 2024

A 3D model of the crustal structure of the region, which includes the Chukchi Borderland with the adjacent ocean and the Chukotka‒Alaska Shelf, has been compiled and calculated. The peculiarity of the crustal structure is the three-sided isolation of the Chukchi Borderland and presence of a transitional area from the south connecting the Chukchi Borderland with the Chukotka‒Alaska Shelf. The connection between the Chukchi Borderland and the Wrangel Rise of the Chukchi Shelf is traced through the North Chukchi Rise located between the North Chukchi Trough and the Hanna Trough. A clockwise rotation of the Chukchi Borderland began in the Early Cretaceous, because basalts at the bottom of the sedimentary strata sections along the eastern and southern boundaries of the Chukchi Basin have a reversed magnetization, i.e., their outpouring occurred before the beginning of the Cretaceous superchron, earlier than 121 Ma. Near the upper boundary of the Neocomian, there was a large-scale shear displacement of crustal blocks along the eastern boundary of the Chukchi Rise, which had a thrust pattern before that. The 3D model demonstrates that the Chukchi Borderland and the Chukchi Basin are the natural components of the continental margin, as they have a strong geological connection with the continental masses of the Chukchi Shelf.
Geology and Hydrocarbon Potential of the Subsalt Deposits of the Astrakhan Arch in the Caspian Petroleum Province: Results of Comprehensive Study
Authors: Volozh Yu. A. , Abukova L. A. , Antipov M. P. , Komarov A. Yu. , Merkulov O. I. , Patina I. S. , Rybalchenko V. V. , Soin D. A. , Titarenko I. A.
Published: December 2024

The article summarizes the results of the authors’ work on the comprehensive substantiation of the geological, tectonic, and geofluid-dynamic conditions for generating and accumulation of hydrocarbons in the subsalt floor of the Astrakhan Arch inside the Caspian oil and gas Province.
We analyzed a significant amount of archival geological and geophysical data and materials such as (i) an array of regional seismic profiles; (ii) gravity and magnetic exploration data of different scales; (iii) results of deep drilling.
Specific seismic geological bodies that are capable of serving as oil and gas reservoirs have been identified. For the first time in creating the geological model of the Astrakhan Arch, its location within the autoclave hydrocarbon system of the subsalt floor of the Central subprovince of the Caspian oil and gas Province (within the Astrakhan-Jambay oil and gas accumulation zone) has been taken into account. This allowed the authors to substantiate the geofluid dynamic nature of the number of large non-structural-type oil and gas reservoirs boundaries. It is opening up new possibilities for predicting oil and gas fields, including those with low sulfur content. Several generation-accumulation mini-hotbeds have been identified on the Astrakhan Arch, and in three of them - reservoirs with increased probability of discovering oil and gas fields. The main result of the study is the refinement of the initial total geological resources of hydrocarbons of the Astrakhan Arch and adjacent areas.
The role of abiotic and biotic factors in population dynamics of lepidopteran miners
Authors: Ermolaev I. V.
Published: December 2024

The individual development of most species of lepidopteran miner caterpillars is associated with one plant specimen. The development of all permanent miners is limited to one leaf, most facultative miners – to one canopy. Unlike a free-living phyllophage, the leaf miner caterpillar cannot change the host plant, for example, if there is a shortage of food due to overpopulation. This determines the existence of mortality factors dependent on population density: both through intrapopulation competition of caterpillars and through the physiological state of the host plant. Among the representatives of the third trophic level, parasitoids are of greatest importance for the population dynamics of mining lepidopterans. The species diversity of miner parasitoid complexes among phytophagous insects is the highest. The functioning of the parasitoid complex is associated with structural and functional transformations over time. The mortality of caterpillars from pathogens is low.
Effect of lighting conditions on the reproductive success of platanthera bifolia (l.) Rich. (orchidaceae) on the northern border of the range (komi republic)
Authors: Kirillova I. A. , Kirillov D. V.
Published: December 2024

Abstract – The influence of illumination conditions on the reproductive characteristics of the rare orchid Platanthera bifolia (L.) Rich has been studied on the territory of the Komi Republic, where the species is located on the northern border of its range. In 2023, five populations of the species were surveyed in habitats with varying of the level of canopy closure (from 6.5 to 82.3%). It was revealed that according to the gradient of increasing of the level of canopy closure, there is a decrease in the values of some indicators of reproductive success – the number of flowers, the proportion of generative plants and the main indicators of seed productivity.
Partial voicing neutralization in unstressed stop-nasal sequences
Authors: Munteanu A. , Kim Y. , Li K. , LeBrun B. , Livolsi S. , Mundie J.
Published: December 2024

We present the results of a production experiment that explores the realization of voicing in English stop-nasal sequences, a phonological environment with a low functional load. The results imply a separation between primary and secondary voicing cues. Primary cues – aspiration and vocal fold vibration during stop closure – robustly distinguish underlyingly voiced stops from and underlyingly voiceless ones. Meanwhile, secondary cues – vowel duration and stop closure duration – are limited in their use by phonological position or absent entirely. A principal component analysis of the data indicates that all speakers occasionally produce tokens that are ambiguous in voicing cues.
On the syntax and usage of glossonyms in memes and reels
Authors: Tanase-Dogaru Mihaela
Published: December 2024

The paper looks at three major contexts of occurrence for non-standard glossonyms, i.e. in internet reels and memes, which are identified as: Verb + glossonym proper (of the type ‘waits in Spanish’), Manner-of-speaking Verb + covert glossonym (of the type ‘screams in teenager’), and Verb + like X glossonym (of the type ‘stares in wife’). Building on the syntactic analysis in Tănase-Dogaru (2024), the paper shows that all three types of constructions involve the presence of a covert classifier LANGUAGE or WAY. Moreover, all three types of constructions involve the presence of the preposition ‘in’, which, unlike standard glossonym constructions, where it disambiguates between an individual-level and a stage-level reading, introduces an ambiguity between a ‘like X’ and a ‘language X’ reading, which in turn triggers humorous effects.
Delinquency-associated stereotypes in Gypsy jokes and their connection to social aspects
Authors: Tudor (Uretu) Noemi
Published: December 2024

Ethnic humour was scarcely addressed by Romanian studies. Therefore, I propose an analysis of Gypsy jokes, that considers a general linguistic perspective, but the broadest dimension is the pragmatic one. The study focuses on 100 ethnic jokes that portray the Gypsy as a main character. I categorised these jokes according to the main topic they present. From a methodological point of view, I use the Intersecting Circles Model (Yus 2013a, 2013b, 2016 etc.), as it operates with the three dimensions found in ethnicity-centred humour (make-sense frame, cultural frame, and utterance interpretation). The quantitative approach illustrates the number of jokes found in each category as a main theme or as a complementary one. The qualitative analysis copes with delinquency-associated stereotypes: theft, begging, lying, dishonesty, metal obsession, as well as their main cause considered by sociologist – poverty. The paper also introduces a terminological distinction – hypo-stereotype vs hyper-stereotype.
Coding and robotics to support linguistic and non-verbal interactional practices in Italian preschools: the powerful effect of small group situations
Authors: Monaco C. , Ceol T. , Mich O.
Published: December 2024

The research started in 2020-2021 and involved 18 Italian preschools: 3-to-6-year-old children have been introduced to experiences of coding and robotics (BeeBot, Cubetto, Lego WeDo 2.0, i-Code). The study aimed at promoting social and discursive interaction among kids within mixed by age small group situations (4-5 children), for improving and increasing their knowledge co-construction. It was composed by different phases that interconnected teachers’ training and school educational practices. Some initial results show that: a) educational robotics represented an effective tool for promoting discursive practices where linguistic and non-verbal dimensions complemented each other; b) within a specific educational planning, coding and robotics allowed teachers to organize learning contexts where children could act and improve several intelligences. This process was always developed within small group situations, where children could “mix and exchange” their individual intelligences.
The Efficacy of Baricitinib as a Treatment Option for Alopecia, In Terms of Promoting Hair Regrowth and Improving Patient Reported Outcomes
Authors: Patel Bhaumik , Gollapudi Abhiram , Gollapudi Samrat , Banala Srinidhi , Mathew Brian Joseph , Patel Prince
Published: December 2024

Background: Alopecia, an autoimmune condition characterized by hair loss, significantly impacts millions globally, often leading to psychological distress such as anxiety and depression. Current treatments are variably effective and frequently associated with adverse effects that restrict long-term use. This study evaluates the efficacy of Baricitinib, a Janus Kinase inhibitor, in treating severe alopecia, focusing on hair regrowth and patient-reported outcomes.

Methods: This research synthesized data from recent publications (2018-2023) including clinical trials, reviews, meta-analyses, and systematic reviews, sourced from databases such as PubMed, Springer, and Elsevier. The inclusion criteria focused on recent studies in English evaluating Baricitinib's effectiveness in severe alopecia cases. The primary outcome measures were the extent of hair regrowth and the change in patient-reported outcomes.

Results: The analysis included results from the BRAVE-AA1 and BRAVE-AA2 trials, which showed significant hair regrowth in patients as evidenced by improved Severity of Alopecia Tool (SALT) scores. Notably, patients treated with baricitinib demonstrated a marked percent change in SALT scores and a higher proportion achieving an absolute SALT score of ≤10 within 36 weeks compared to the placebo. The treatment was well-tolerated with minimal adverse effects reported.

Conclusion: Baricitinib has shown promising results in promoting significant hair regrowth in patients with severe alopecia, with minimal side effects, making it a viable treatment option. The FDA has approved Baricitinib for this indication. However, further research is necessary to evaluate the long-term safety of Baricitinib and to confirm these findings in a larger cohort.
Wide Awake Local Anesthesia No Tourniquet (WALANT) Is More Effective at Decreasing Pain Compared to Distal Nerve Block With a Tourniquet During Carpal Tunnel Release Surgery: A Systematic Review and Pooled Analysis
Authors: Elias Jonathan
Published: December 2024

Background: Carpal tunnel release (CTR) is one of the most common upper extremity procedures, reaching 400,000 - 600,000 procedures yearly in the United States. With such a common procedure, it is pertinent that every step is as comfortable for the patient as possible. Many patients report discomfort due to the usage of a tourniquet during the anesthesia process. However, a growing number of physicians are beginning to use the wide awake local anesthesia no tourniquet (WALANT) approach. WALANT utilizes a distal nerve block (commonly Ropivacaine), Lidocaine, Epinephrine, but no tourniquet. The more commonly used approach utilizes the same distal nerve block, in combination with a tourniquet. To date, there have been no systematic reviews or meta-analyses evaluating whether the WALANT approach yields lower pain than a distal nerve block with a tourniquet during CTR.

Purpose: We conducted a systematic review and pooled analysis comparing the WALANT technique to using a tourniquet with a distal nerve block on the pain experienced by patients during carpal tunnel release.

Methods: This systematic review and pooled analysis followed the 2020 PRISMA guidelines. Five online databases (Cochrane, Embase, Scopus, Web of Science, Pubmed) were screened for studies that included intraoperative Visual Analogue Scale (VAS) or Numeric Rating Scale (NRS) scores of patients having CTR with either the WALANT approach or a tourniquet with a distal nerve block. After the screening process, 2 randomized controlled trials (RCTs) were included in the final analysis, yielding a total of 90 distinct patient evaluations.

Results: The results portray a strong clinical significance (Cohen’s d = 1.03, 95% CI 0.59-1.47) on pain reduction, in favor of utilizing the WALANT technique.

Conclusion: Our systematic review and pooled analysis serves as a preliminary study in the exploration of the WALANT technique, specifically for CTR. The results illustrate that WALANT is a promising method in reducing patient pain during this procedure, portrayed by the large effect size between using a tourniquet with a distal block, and WALANT. Future RCTs are needed to control for the drug and dose of nerve block used, and to increase the sample size.
Discourse competence: A key to enhancing IELTS scores for Vietnamese students
Authors: Lien Tran Thi Ngoc
Published: December 2024

IELTS has been one of the most reliable and widely selected test formats worldwide. In Vietnam, this test has been increasingly popular and used as a criterion for university admission. For its increasing significance, the question about how to improve the test scores has attracted attention from the publicity, and there came an agreement that improvements in language competence or proficiency work. There have been thousands of books published and millions of websites created to provide hints, tactics, and strategies for potential test takers. In this paper, the researcher would like to present her study, which delved into the effects of developing discourse competence for IELTS test takers. Sixty university students were randomly chosen and divided into two groups: the control group and the experimental one. They participated in a 12-week action research project. A survey questionnaire was assigned to get their opinions about the teaching approach. Findings indicate that students in the experimental group got better overall IELTS scores than those in the control group. Writing and speaking tests scored higher than the reading and listening ones. Mastery of discourse features affected reading and listening task types at varying degrees. Most agreed that improvements in discourse competence enabled them to satisfy the marking criteria of the writing and speaking test papers. For receptive skills, which are reading and listening, recognizing discourse patterns empowered them to control the time better and increase the accuracy of their answers. However, there were disagreements about incorporating discourse components into the existing syllabus. The difference in student competence, learning time, and motivation did affect the effectiveness of this pedagogy.
Der letzte Weg. Aufzeichnungen deutschsprachiger Juden
Authors: Kaiser Wolf
Published: December 2024

Andrea Löw (2024): Deportiert. „Immer mit einem Fuß im Grab“. Erfahrungen deutscher Juden Frankfurt a.M.: S. Fischer, ISBN 978-3-10-397542-0, 364 Seiten, 26,00 Euro
Reichtum rückverteilen!
Authors: Segbers Franz
Published: December 2024

Christoph Butterwegge (2024): Umverteilung des Reichtums Köln: PapyRossa Verlag, ISBN 978-3-89438-831-7, 223 Seiten, 16,90 Euro
atendimento às crianças e adolescentes vítimas de violência sexual na microrregião de Ubá
Authors: Loures Juliana Imperatori , Marcellos Cíntia  Fernandes
Published: December 2024

O trabalho analisou o atendimento às crianças e adolescentes vítimas de violência sexual nas 17 cidades da microrregião de Ubá, considerando protocolos previstos e dados de notificação. Realizou-se uma pesquisa bibliográfica e documental com os documentos orientadores publicados entre 2013 e 2023 e os dados de notificação do Portal de Dados Abertos de Minas Gerais no período. Os resultados evidenciaram um conjunto de previsões de atendimento que, contudo, enfrentam dificuldades na efetiva aplicação. Os indicadores registram 171 casos no período observado, seguindo tendências do cenário nacional. Não obstante avanços em relação ao Plano Nacional de Enfrentamento à Violência Sexual contra Crianças e Adolescentes, os resultados apontam a necessidade de outras medidas de enfrentamento ao problema.
Efek Asupan Antioksidan Kaya Enzim Cytochrome P450 2E1 (CYP2E1) Terhadap Kadar Leukosit
Authors: M. Subandi Baharuddin , Zurimi Suardi , Rohim Tualeka Abdul , Bella Puspitaloka Nanda
Published: December 2024

Tubuh manusia memiliki sistem antioksidan yang berasal dari enzimatik, tetapi kapasitasnya tidak selalu cukup jika jumlah radikal bebas berlebihan. Pendekatan asupan antioksidan kaya enzim CYP2E1 dilakukan untuk membantu tubuh dalam mendetoksifikasi metabolit benzena untuk diekskresikan dari tubuh. Tujuan penelitian ini adalah menganalisis efek asupan antioksidan kaya enzim CYP2E1 terhadap perubahan kadar leukosit pekerja home industry sepatu Tambak Osowilangun Surabaya. Jenis penelitian ini adalah penelitian pre-eksperimen dengan rancang bangun penelitian one group pre-test post-test. Sampel dalam penelitian menggunakan total population sampling yaitu seluruh pekerja home industry sepatu Tambak Osowilangun sebanyak 27 orang. Intervensi yang diberikan berupa pemberian suplemen antioksidan berbentuk serbuk sebanyak 15 gram dan dikonsumsi sebanyak 2 kali sehari selama 5 hari berturut-turut. Pengukuran kadar leukosit dilakukan dengan pengambilan sampel darah pekerja yang dilakukan pada hari pertama sebelum intervensi dan hari ke lima setelah intervensi. Hasil penelitian menunjukkan terjadi perubahan pada keseluruhan kadar leukosit pekerja setelah diberikan perlakuan. Terjadi peningkatan pada jumlah pekerja yang mencapai kadar leukosit normal (92,6%). Namun, masih terdapat beberapa pekerja yang tidak mencapai kadar leukosit normal (7,4%) meskipun telah mengalami perubahan kadar leukosit. Kesimpulan dari penelitian ini adalah pemberian intervensi efektif dalam mengubah kadar leukosit pekerja menjadi normal berdasarkan jenis kelamin perempuan, berusia produktif, memiliki IMT normal, tidak merokok, melakukan aktivitas/latihan fisik, dan tidak menggunakan APD. Pekerja disarankan rutin berolahraga yang sesuai dengan preferensi dan kebutuhan tubuh, menerapkan pola makan seimbang dan mengkonsumsi makanan kaya antioksidan, menggunakan kuas dalam mengaplikasikan lem, serta menggunakan APD yang sesuai standar berupa masker N95, sarung tangan, dan apron.
Kata kunci : kadar leukosit, antioksidan, CYP2E1
Analisis Kandungan Gizi Dan Daya Terima Panelis Terhadap Kudapan Gyobas Berbasis Ikan Bandeng Sebagai Upaya Pencegahan Anemia Dan Stunting Pada Remaja
Authors: Sunarto Sunarto , Chaerunnimah Chaerunnimah , Irma Rita
Published: December 2024

Kualitas kandungan nilai gizi ikan bandeng berpotensi dimanfaatkan dalam pengembangan produk makanan untuk mencegah Anemia ataupun stunting. Tujuan penelitian ini untuk mengetahui nilai gizi dan tingkat penerimaan panelis terhadap aspek warna, aroma, tekstur dan rasa kudapan Gyoza Bandeng (Gyobas). Responden panelis sebanyak 30 orang. Daya terima produk dinilai menggunakan form skala uji hedonik yang terdiri dari sangat tidak suka, tidak suka, agak suka (netral), suka dan sangat suka. Kandungan gizi produk dinilai mengunakan tabel komposisi pangan Indonesia (TKPI), 2020. Analisis kandungan gizi menggunakan TKPI menunjukkan bahwa kudapan Gyobas dalam 100 g mengandung energi 261,5 kkal, protein 11,5 g, lemak 11,5 g, karbohidrat 8 g, serat 3,5 g, Vitamin B1 0,5 mg, vitamin C 6,0 mg, Karoten total 398g, abu 0,5 g, Kalsium 20 mg, fosfor 74 mg, besi 1,0 mg, natrium 285 mg, kalium 128 mg, tembaga 11 mg, zink 0,5 mg. Hasil uji organoleptik menunjukkan bahwa kudapan Gyobas dapat diterima dengan persentase penerimaan skala suka hingga sangat suka, pada aspek warna total tingkat penerimaan sebesar 87%, aspek aroma 93%, aspek tekstur 93% dan rasa 100%. Berdasarkan rata-rata nilai hedonik pada aspek warna, aroma, tekstur dan rasa, masing-masing sebesar 4,2; 4,4,; 4,3 dan 4,6. Nilai gizi kudapan Gyobas cukup lengkap yang meliputi gizi makro dan mikro sehingga dapat menjadi alternatif kudapan berbasis pangan lokal sebagai upaya untuk mencegah masalah gizi (Anemia atau Stunting) pada remaja. Secara keseluruhan, Gyobas disukai dan dapat diterima oleh panelis, namun aspek rasa memiliki tingkat penerimaan yang paling tinggi.
Kata Kunci: Daya terima, Ikan Bandeng, Gyoza Bandeng, Gyobas, Anemia dan Stunting
Adverse Effects of Oral Administration of Bisphenol A-Induced Toxicity on Adult Male Rat Liver and Testis With the Protective Roles of Herbal Teas
Authors: Sami Rokayya , Abushal Suzan A. , Aljumayi Huda , Almujaydil Mona S. , Harasani Ahlam A. , Helal Mahmoud , Al-Eisa Rasha A. , Alanazi Mohammad A.
Published: December 2024

Bisphenol A (BPA) is a monomer widely used in our living environment to manufacture many chemical products. Mammalian cells are exposed to it at high levels, which has toxic and estrogenic consequences. Moreover, BPA exposure during prenatal and neonatal development results in defects in the male and female reproductive systems, abnormal meiotic development in fetal oocytes, and pregnancy complications. The principle of the current study was to study the adverse effects of the oral administration of BPA on the liver and testis toward adult male rats with the protective roles of herbal teas. A comparative study was conducted on 40 adult rats. Groups were coded as RT/BPA, GT/BPA, and BT/BPA, for red, green, and blue herbal teas, respectively. lowest values for AST (58.71 mU/mL), ALP (1.51 mU/mL), and GGT (21.12 U/L). Similarly, RT/BPA and BT/BPA groups were detected (4.11 and 4.12 mg/100 mL) for creatinine levels as compared to the vehicle control group. While rats in BT/BPA and GT/BPA groups showed similar values to the vehicle group (45.02 and 118.28 mg/dI) for HDL and TC quantities, respectively. The present research work established the protecting rolls of herbal teas due to the antioxidant properties especially green tea which preserved GPx value (88.22 nmol/mg), testosterone (1.80 ng/ml), and red tea which preserved CAT value (101.18 U/mg), while blue tea preserved MDA and SOD values (0.81 nmol/mg and 7.18 U/mg), respectively. The BPA oral administration with herbal teas reduced toxicity on the liver and testis due to free radical scavenging effects.
From viper jelly to artificial pancreas – a history of diabetes treatment
Authors: Banaszak Michalina , Górna Ilona , Przysławski Juliusz , Drzymała-Czyż Sławomira
Published: December 2024

Diabetes, a pervasive lifestyle ailment with roots tracing back to ancient civilizations like India, Egypt, China, and Arabia, has captivated human understanding for centuries. Early attempts to grasp its complexities involved restrictive diets and herbal remedies, reflecting a lack of knowledge of the mechanisms underlying the disease. Remarkable milestones have marked the journey of diabetes treatment. A monumental shift occurred in 1921 when Frederick Banting and Charles Best's isolation of insulin heralded a new era in diabetes treatment, vastly enhancing patient longevity and comfort despite the initial discomfort of injections. From the groundbreaking synthesis of the insulin gene to the advent of insulin pens and analogues, each innovation has expanded therapeutic avenues for those affected. In the 21st century, medical engineering has evolved further, with technologies like continuous glucose monitoring systems and closed-loop pumps—called "artificial pancreas"—ushering in unprecedented glycemic control and quality of life for type 1 diabetes patients. For those with type 2 diabetes, the focus has shifted towards a comprehensive approach encompassing new and effective pharmacotherapy and lifestyle adjustments. Crucially, amidst the continuum of advancements, the cornerstone of diabetes management remains rooted in education and lifestyle adaptations. Regular meals, weight management, consumption of low-glycemic carbohydrates, exercises, and meticulous foot care are essential against debilitating complications. Despite historic and ongoing challenges, advances in diabetes treatment provide hope for increasingly modern therapies and outcomes, underscoring the importance of education and lifestyle changes in the fight against this chronic disease.
Study on acute toxicity and subacute toxicity of ethanol extract of Ajania purpurea C. Shih
Authors: Zhang Yichi , Dongzhi Zhuoma , Yuan Ruiying , Gui Mingan , Ji De , Zhang Songbai , Zhou Hongmei
Published: December 2024

Abstract
Background: Ajania purpurea. C. Shih commonly used in traditional Tibetan medicine. It is known for its therapeutic effects on conditions like lung heat, pharyngitis, and thoracic empyema. Toxicity evaluation includes acute toxicity test, subacute toxicity test, subchronic toxicity test, reproductive and developmental toxicity test, etc. Toxicity test is one of the important indicators to determine its safety.Methods: To assess the acute and subacute toxicity of ethanol extract from A. Prpurea.whole plant (EAP), both mice and rats were used to conduct acute and subacute toxicity experiments. Mice were administered a one-time dose of A. purpurea ethanol extract at 2000 mg/kg in acute toxicity study. In subacute toxicity experiments, doses of 200 mg/kg, 400 mg/kg, and 800 mg/kg were administered for 28 consecutive days. The behavior, body weight, organ coefficient, complete blood cell count, blood biochemistry and histopathological section were observed.Results: In the subacute toxicity experiment, SD rats were orally administered A. Prpurea. ethanol extract for a continuous period of 28 days at doses of 200 mg/kg, 400 mg/kg, and 800 mg/kg respectively. The animals' behavior, body weight, organ coefficients, blood biochemical parameters, complete blood count and histopathological changes were observed. The results showed that compared to the control group, the rats treated with 400 mg/kg and 800 mg/kg of Ajania purpurea.C. Shih extract exhibited highly significant differences in blood biochemical liver function, and noticeable pathological changes in organ tissues.Disscussion: Based on the overall experimental results, this study found that A. Prpurea. exhibited no toxicity in terms of acute toxicity.
Novel spectral data for effervescent tablets according to shelf life.
Authors: Meisner Michał , Sarecka-Hujar Beata , Szulc-Musioł Beata
Published: December 2024

To ensure the safety of pharmacotherapy, stability tests are carried out throughout the shelf life of all medicines. An interesting alternative to conventional methods of monitoring the quality of medicinal products is the measurement of reflectance and emissivity. The study aimed to assess the change in emissivity and reflectance for different types of effervescent tablets containing paracetamol and vitamin C. In the study, three types of effervescent tablets of the same product were analysed i.e., unexpired, expired, and stressed tablets. The accelerated aging test was performed for 7 days in a Solarbox 1500 chamber (Italy), in which the tablets were irradiated with simulated sunlight and a temperature of 26⁰C. The reflectance had similar values for both unexpired and expired tablets, but these were higher than for the stressed tablets. The emissivity analyses showed that tablets exposed to UV radiation for 7 days had the highest emissivity value of all types in the spectral range of 1.5-21.0 µm. Using a hyperspectral camera, the differences between the maximum and minimum reflectance values were assessed, as this may reflect the homogeneity of the sample. Homogeneity was similar for unexpired tablets, expired tablets, and tablets stressed for 3 days, they showed better homogeneity than tablets stressed for 7 days. It can be speculated that UV radiation increases the reflectance of the tablets and decreases the homogeneity of the tablets tested.
EFEKTIVITAS PLATFORM DIGITAL BERBASIS GOOGLE SLIDE TERHADAP HASIL BELAJAR PADA PEMBELAJARAN PENDIDIKAN AGAMA ISLAM DI SEKOLAH DASAR
Authors: Suharto Royyanatul Mahbubah , Hosna Rofiatul Hosna
Published: December 2024

Teachers as the frontline of the world of education must be technologically literate, keep up with the latest developments, and adjust and utilize them in learning. The world of education must adapt to this progress to improve the quality of education, especially by adjusting the use of information and communication technology in education, especially in the learning process. And educators are competing to present innovations and new colors in learning. Technology is very helpful in the learning process, the material is so easy to get, training or the learning process can be done online or anywhere, one of which is through the Google Slides platform. This study uses a quantitative approach and a type of True Experimental Design research, used to determine the scores of students from classes that are treated (experimental), and classes that are not treated (control) by improvement. Posttest Only Control Design research design. The results of the research on the Independent Sample T-Test were obtained by Sig. (2-tailed) .000 < 0.05, so there is a significant difference between the learning outcomes in class VI A as a control class that uses conventional media and class VI B as an experimental class that uses Google Slides media. And based on the results of the N-Gain score test, it shows that the average N-gain score for the experimental class (Google Slide-Based Digital Platform) is 87.11 or 87.11% included in the effective category. With an N-gain score of at least 80% and a maximum of 98%. Meanwhile, the N-gain of the control class (conventional method) has an average score of 61.68% and is included in the category of quite effective with a minimum N-gain score of 45% and a maximum score of 78%. Then H0 is rejected and HA is accepted.
3D-MTF of Computed Tomography (CT) Images Using a 3D-Wire Phantom: The Impact of Tube Voltage Variations
Authors: Yuliana Lakapu  , Choirul Anam  , Wahyu S. Budi  , Betha Sri Wulandari
Published: December 2024

Key exposure factors, such as tube voltage are critical in CT examinations as they will impact the quality of the images produced by the CT scan. Spatial resolution is one of the parameters that can be used to determine image quality. The purpose of this study is to evaluate the impact of tube voltage in spatial resolution in three axes (x, y, z) using an in-house wire phantom. The results show that MTF 10% in the axial plane (x-y) is approximately identical (approximately 0,70 mm) for various tube voltages 80, 100, 120, and 140 kV. The same results were observed at the coronal and sagittal plane (z-axis), although they exhibit more variation than axial plane the differences in values between tube voltages are not significant.
АНАЛІЗ ФАКТОРІВ КОН'ЮНКТУРИ МІЖНАРОДНОГО РИНКУ ЧАЮ
Authors: Дунська Алла , Буртова Анастасія
Published: December 2024

Стаття присвячена аналізу кон'юнктури міжнародного ринку чаю, який є важливим сегментом світової економіки. Проаналізовано ключові фактори, що впливають на формування цін та обсягів виробництва, включаючи економічні, політичні та кліматичні чинники. Виявлено високу залежність ринку чаю в Україні від імпорту, особливо від шрі-ланкійської сировини, що створює потенційні ризики для стабільності постачання. Розглянуто основні тенденції в структурі експорту чаю на світовому ринку, що дозволяє краще зрозуміти фактори, які визначають кон'юнктуру ринку в умовах сучасних викликів. Дослідження має практичну цінність для підприємств галузі, які прагнуть адаптуватися до змін на світовому ринку.