bluuebunny/crossref_metadata_2025 huggingface dataset:
Laboratórios de Matemática na rede pública: relatos de experiência sob a ótica da práxis docente de professoras de Matemática
Authors: Schneider Cintia , Reisdoefer Deise Nívia , De Oliveira Cristina Aparecida Gabriel
Published: January 2025

Laboratórios de Ensino de Matemática são, além de espaços físicos, oportunidade de desenvolvimento de mediações pedagógicas como um ambiente propício para investigação, experimentação e discussões, inclusive de forma interdisciplinar. Seguindo essa prerrogativa, o objetivo principal desse artigo é apresentar um relato empírico teórico de duas docentes atuantes em Laboratórios de Ensino de Matemática de uma escola pública, como meio de socializar as experiências oriundas da prática diária com as demandas da função. De forma geral, as atribuições dessas profissionais são diversas, mas o relato crítico se atém principalmente ao desenvolvimento de Projetos para Feiras de Matemática. Dentre algumas considerações, destaca-se a relevância do papel do professor de Laboratório e suas intervenções como meio de tornar o processo de ensino e aprendizagem de matemática mais dinâmico e significativo.
Subsidi Energi: Tantangan Penyaluran BBM, LPG 3 kg, serta Dukungan Terhadap Kendaraan Listrik
Authors: A’yun Qurrata , Akhmadi Muhammad Heru , Wati Erlita Nurma
Published: January 2025

Energi hijau menjadi strategi dalam mengendalikan perubahan iklim secara global. Beberapa negera termasuk Indonesia telah mendorong pertumbuhan energi hijau dengan mengendalikan penggunaan energi fosil dengan tetap memperhatikan kebijakan pembangunan yang dapat memberikan multiplier effect terhadap pertumbuhan ekonomi. Penelitian ini bertujuan untuk mengetahui dampak kebijakan subsidi energi pada energi fosil dan elektrik yang diberikan di Indonesia.  Penelitian ini menggunakan pendekatan kuantitatif dan kualitatif (mixed method), dengan teknik analisis regresi melalui Aplikasi STATA 18 dan focus group discussion. Hasil penelitian menunjukkan bahwa masih terdapat beberapa tantangan yang dihadapi pemerintah berkaitan dengan belanja subsidi energi, yaitu terjadinya penyaluran subsidi energi yang tidak tepat sasaran (inclusion error) yang menyebabkan penanggulangan kemiskinan melalui program subsidi energi belum sesuai harapan. Meskipun demikian, terdapat beberapa solusi permasalah dalam upaya meningkatkan kualitas kebijakan dan mulai memikirkan adanya opsi subsidi terhadap kendaraan listrik.
Urgensi Reformasi Hukum Lingkungan Terhadap Perubahan Iklim di Indonesia
Authors: Mahardhika Zerlina Mendy , Hapsari Ivana Mirella , Rajib Rayi Kharisma
Published: January 2025

Perubahan iklim yang disebabkan oleh aktivitas manusia seperti pembakaran bahan bakar fosil, telah menjadi isu global yang mendesak. Dampaknya mencakup peningkatan suhu global, cuaca ekstrem, dan ancaman terhadap ekosistem. Perubahan iklim di Indonesia sudah terasa, seperti perpanjangan musim hujan dan peningkatan hari-hari kering di beberapa wilayah. Hukum lingkungan memegang peran penting dalam dalam menghadapi kompleksitas perubahan iklim, namun sering dianggap tidak cukup memadai. Oleh karena itu, reformasi hukum lingkungan menjadi  penting untuk mengatasi tantangan tersebut. perubahan iklim, serta aspek keadilan dan keberlanjutan bagi semua pihak yang terlibat. Metode penelitian yang digunakan adalah pendekatan yuridis normatif. Tulisan ini bertujuan untuk membahas  urgensi reformasi hukum lingkungan terhadap perubahan iklim di Indonesia. Langkah-langkah reformasi yang efektif dan berkelanjutan menjadi kunci dalam menjawab tantangan tersebut, dengan fokus pada perlindungan dan pengelolaan lingkungan hidup. Melalui adanya reformasi legislasi, reformasi pengadilan dan penegak hukum, dan dukungan terhadap upaya inovatif dan pembangunan yang berkelanjutan  diharapkan dapat tercipta lingkungan hidup yang lebih berkelanjutan bagi generasi mendatang. Hukum lingkungan penting untuk mitigasi dan adaptasi perubahan iklim, namun sering dianggap tidak memadai apabila penegakan hukum terhadap pelanggaran lingkungan dilakukan secara tidak konsisten dan tidak semestinya. Oleh karena itu, reformasi hukum lingkungan terkait perubahan iklim di Indonesia sangat diperlukan, termasuk pembaruan legislasi, peningkatan kapasitas pengadilan, perlindungan ekosistem, kepatuhan terhadap regulasi, kolaborasi internasional, dukungan inovasi, dan partisipasi masyarakat.
Analisis Kebijakan Transportasi dalam Mengatasi Kemacetan di Kota Palembang
Authors: Putri Hesti Intan , Arenawati  , Nugroho Kandung Sapto
Published: January 2025

Kemacetan adalah salah satu isu strategis pembangunan di Kota Palembang, hal ini disebabkan oleh perkembangan jumlah kendaraan pribadi yang tidak disertai dengan perluasan ruas jalan. Pemerintah kota Palembang telah melaksanakan berbagai upaya untuk mengatasi kemacetan di berbagai titik di Kota Palembang, seperti membangun flyover dan underpass, serta menyediakan transportasi publik non jalan raya. Penelitian ini bertujuan untuk menganalisis kebijakan yang sudah dilaksanakan oleh Pemerintah Kota Palembang dan meninjau sejauh mana keberhasilan kebijakan tersebut dalam mengatasi kemacetan di Kota Palembang. Metode penelitian yang digunakan dalam penelitian ini ialah studi literatur review. Sumber data diambil dari empat artikel ilmiah di Google Scholar yang memenuhi kriteria inklusi yang telah ditegakkan, laporan lembaga terkait, dan situs berita online. Hasil penelitian menunjukkan bahwa satu flyover dan underpass efektif dalam mengatasi kemacetan, sedangkan LRT terus mengalami kenaikan jumlah penumpang namun belum diikuti dengan penurunan jumlah kendaraan pribadi.
Diatom diversity and ecology as indicators of spring quality in the southeastern Basin of Arequipa – Peru
Authors: Castillo Acobo Luz Virginia , Ochoa Torres Nemesio Alberto
Published: January 2025

The taxonomic composition, relative abundance, richness, diversity, and equity of the epilithic diatoms present in the springs of the southeastern basin of Arequipa were determined, using ecological indices. The diatom biological index (DBI) was estimated, providing information on freshwater bodies’ quality. The correlation between the important environmental variables and the calculated indices is established.
Quality of primary care for people with mental disorders
Authors: Peralta Jimenez Myrian Lastenia , Chavez Jimenez Walter Rolando , Acosta Marino Alex Andres , Gualán Quishpi Maria Diana , Alvarez Pilay Carlos Patricio
Published: January 2025

This study aimed to analyze the quality of primary care provided to individuals with mental disorders. The research was applied, simple and descriptive, and used a non-experimental design. Data were collected through a survey consisting of 30 items. The population included healthcare personnel and their respective patients. The main results indicated that the health center has weaknesses in managing primary care, which reduces the quality of service. To address this issue, a model is proposed to promote the integration of various managerial and operational departments to achieve common goals related to quality of care. The proposed model is based on William Deming's quality dimensions and Marilyn Anne Ray's Bureaucratic Caring Theory.
VISUAL TRENDS IN INTERACTIVE-GAME FORMS OF PROMOTION OF DECORATIVE COSMETICS ON THE EXAMPLE OF A RUSSIAN BRAND IN THE SOCIAL NETWORK VKONTAKTE
Authors: Dikova Ekaterina A.
Published: January 2025

This article examines interactive and game forms of promoting decorative cosmetics in the social network VKontakte and visual trends using the example of the Russian brand Beauty Bomb. The purpose of the study is to identify trends in visual strategies to attract attention to contest posts. The paper examines the theoretical foundations of visual, emotional marketing and gamification in social networks. The study includes a content analysis of the Beauty Bomb brand in the VKontakte community for a certain period and a selection of posts according to the value of the coefficient obtained using the ER formula of the post. The material for the study is the brand’s publications containing interactive and game mechanics (contests, games, surveys). In the course of the work, we form a list of interactive and game forms and identify visual trends in contest posts. The results of the work show that there are visual trends in the use of precedent collages involving influencers, videos with references to films and surreal elements in photographs, which, in combination with interactive mechanics, significantly increase the effectiveness of decorative cosmetics promotion in social networks. The data obtained can be useful for marketers and SMM specialists working in the beauty industry.
APPROACHES TO RESEARCHING THE FEATURES OF PROMOTION OF LIBRARIES IN THE MEDIA SPACE
Authors: Zotov Viktor E.
Published: January 2025

In the modern world, the problem of people losing interest in libraries is clearly expressed. To keep up with the times, physical libraries are actively developing in the media space. But to choose the right path of development, it is necessary to study the main approaches and features of promotion, since modern libraries should use not only traditional methods, but also look for new, innovative ways to attract attention. This is especially true for institutions that continue to operate in the traditional service sector, but at the same time are directly interested in attracting attention to their activities, expanding the range and methods of their media promotion, taking into account the need to expand the audience of stakeholders. In this connection, various mechanisms for promoting libraries in modern society are considered.
PECULIARITIES OF ADVERTISING TEXT ON THE SPORTS.RU MEDIA RESOURCE
Authors: Gorbachev Ivan M.
Published: January 2025

In this article the author turns to the analysis of advertising texts presented on the electronic resource sports.ru during the European Football Championship 2024. The analysis of the selected materials results in the classification of genre, stylistic, lexical,
morphological and syntactic resources of the advertising text. The author concludes that the advertising texts placed on this resource demonstrate a high degree of adaptation to current events and interests of the target audience. The use of a variety of genre formats, such as announcements, interviews and analyses, allows to effectively attract the attention of readers. Stylistic techniques including metaphors, epithets, hyperboles and others that create an emotional connection with the audience, while lexical and morphological features emphasise the dynamism of the sports context. The syntactic structure of the texts ranges from simple to complex constructions, which
contributes to the diversity of information perception by individual target audiences. Thus, the study shows that on the information portal ‘Sports.ru’ advertising texts attract readers’ attention, through various types of information materials about sports events natively inform the audience about the advertised brands, thus contributing to the creation of a positive emotional connection of the target audience from the interaction both with this resource and with the brands integrated in the advertising messages.
CREATION OF JOURNALISTIC MATERIAL: STORYTELLING AS A RECEPTION IN REGIONAL MEDIA
Authors: Shishkova Anastasia А.
Published: January 2025

In recent years, storytelling has become an important tool in the arsenal of journalists. This is especially evident in the materials of regional media. This article examines the role of storytelling in the creation of journalistic materials, analyzing its impact on the perception of information and audience involvement. Examples of the use of storytelling in regional media are considered and key elements that contribute to the effective use of this technique are identified. The conclusion of the study is that storytelling elements can be used in materials of various genres, which will increase the digestibility of the text by readers and make it more exciting. Correctly using storytelling elements, you can not only awaken the reader’s interest in the story, but also evoke empathy for the characters or a more complex emotional reaction – suspense.
PROFESSIONAL AND NON-PROFESSIONAL REVIEWS OF THE PLAY IN THE MODERN MEDIA SPACE: THE COMPARATIVE ASPECT
Authors: Budau Marina R. , Antropova Vera V.
Published: January 2025

Due to the development of information and communication technologies, today any user can become an author of media texts of different genres and different quality, trying himself, including in the field of analytical journalism, theater criticism. The relevance of the study is due to the contradiction between the requirements for a highquality review and the everyday communication practices of users who offer their reviews to the audience on different media platforms. We assumed that each of the review types under consideration, having a set of certain features, fulfills its tasks, and for this purpose we compared them based on the identified relevant criteria. As a result of the comparison, the authors came to the main conclusions: professional review not only corresponds to the generally recognized genre canons ( analyticity, objectivity and impartiality, criticality, evidence, retrospectivity, evaluativeness), but also continues to support institutional (developed by journalism as a special institution) rules and conventions (agreements) in the modern media space; An unprofessional review is mostly based on an emotional and evaluative beginning, representing a simplified, reduced version of the first one, which brings it closer to a review of any object of media discourse.
NEW MEDIA AS INSTRUMENTS OF INTEGRATION PROCESSES IN THE MODERN MEDIA SPACE
Authors: Valyulina Ekaterina V.
Published: January 2025

The article examines the possibilities of new media in organizing integration processes in modern society. It is noted that in the format of new media, interaction and integration are carried out between different subjects in the paradigms of “personality – personality”, “personality – media”, “media – media”, “media – state”, “state – personality”, etc. Integration processes that are becoming natural in a constantly updated media space cannot but have a psychological impact on people, especially on the younger generation, for whom the concept of boundaries is no longer as important as for older people, and the
boundaries themselves are not as immutable. The interactivity of new media helps users develop a belief in their own importance, their ability to influence other people and global social processes.
INCLUSION IN THE INFORMATION AGENDA OF SOCIOPOLITICAL MEDIA AND MEDIA SPECIALIZING IN SOCIAL JOURNALISM
Authors: Kurnakova Darya A. , Belenko Victoria E.
Published: January 2025

The article presents the representation and content of “inclusion” in media of different orientations: socio-political and specialized. Using framing, we analyze the content, informational contexts, “informational occasions,” and the artistic methods that the
media use to cover this topic. The goal of the study is to explore how the media influence the formation of an inclusive culture in society and what kind of “portrait of a contemporary” they portray. Using the cluster analysis method, we identified different contexts (covering the theatrical success of people with disabilities, the opening of new inclusive schools and texts comparing correctional and inclusive schools – in socio-political press; covering social interaction between people with disabilities and neurotypical individuals, covering the self-realization of people with disabilities, covering problems of inclusive education – in specialized press), which allowed us to identify a specific concept of “inclusion” in each type of media. The two types of media present completely different contexts of inclusion. While specialized media “personify” inclusion – social issues are revealed through stories of specific individuals – socio-political media tend to favor “general” narratives, where the actor is not so much a person with a disability but rather a society that “accepts” them.
Edukasi Senam Hamil Pada ibu Hamil Trimester III Sebagai Persiapan Persalinan di Desa Oben Kecamatan Nekamese Kabupaten Kupang
Authors: Pratiwi Endah Dwi , Ahmad Siti Nur Asyah Jamillah , Jumetan Mili Arthanedi
Published: January 2025

Pregnancy exercise is a fitness program intended for pregnant women. Pregnancy exercise aims to prepare and train the muscles so that they are used to function optimally in normal childbirth. Implementation of pregnancy exercises carried out by pregnant women in the third trimester can reduce discomfort in complaints of swelling in the legs, back pain, lower back pain, leg cramps and difficulty sleeping. The results of the study show that there is an influence of pregnancy exercises on the discomfort of low back pain, back pain, swelling in the legs and cramps. on the feet. This socialization and training activity on pregnancy exercise was carried out on January 17 2024 in Oben Village, Nekamese District, Kupang Regency, involving lecturers and program holders at the local health center as well as cadres. The participants who took part in this activity were 7 third trimester pregnant women and 3 lecturers as well as 1 program holder midwife and 3 cadres. It is known that the implementation of this community service activity ran smoothly. The results of this activity also show that there has been an increase in information and ability to apply pregnancy exercises. Apart from that, pregnant women also stated that they understood pregnancy exercise and the benefits of facing childbirth.
REVISÃO DE ESTUDOS SOBRE A ETNOMATEMÁTICA E A EDUCAÇÃO QUILOMBOLA: COMO AS COMUNIDADES QUILOMBOLAS UTILIZAM E ENSINAM MATEMÁTICA EM SEUS CONTEXTOS CULTURAIS
Authors: Almeida Ferreira Samara , Roberto Brasil Dos Santos Paulo , José Silva Márcio
Published: January 2025

Este artigo tem como objetivo realizar uma revisão de estudos sobre a etnomatemática e a educação quilombola, com foco em como as comunidades quilombolas utilizam e ensinam matemática em seus contextos culturais. A metodologia utilizada possui abordagem qualitativa, usando a pesquisa bibliográfica como instrumento de coleta de dados. Destaca-se que a educação quilombola integra práticas culturais e conhecimentos tradicionais das comunidades quilombolas, porém, enfrenta desafios significativos na valorização e inclusão dessas práticas no currículo escolar formal. Nesse cenário de dificuldades, a etnomatemática oferece uma abordagem promissora para conectar a matemática com contextos culturais específicos. A revisão dos estudos sobre a etnomatemática e a educação quilombola revela a riqueza e a complexidade dos conhecimentos matemáticos presentes nas comunidades quilombolas, destacam a importância de integrar esses saberes no currículo escolar, promovendo uma educação mais inclusiva e relevante para esses contextos culturais. Como resultados, vemos que as semelhanças entre os textos revisados, como o uso de teóricos como Ubiratan D’Ambrosio e Paulo Freire, indicam um consenso sobre a importância da etnomatemática como ferramenta pedagógica para a valorização sociocultural. No entanto, as diferenças metodológicas e de foco entre os estudos apontam para a diversidade de abordagens possíveis e a necessidade de contínua investigação e diálogo entre pesquisadores e educadores. As limitações metodológicas identificadas, como a superficialidade em alguns aspectos e a necessidade de maior profundidade em outros, reforçam a importância de uma pesquisa cuidadosa e rigorosa e a necessidade de maiores estudos e pesquisas na área, os quais possibilitam novas abordagens.
Low-sodium Chaya Leaf Seasoning Powder with Potassium Chloride Substitution: Nutritional, Antioxidant, and Microbial Quality Assessment
Authors: Senphan Theeraphol , Puangtong Kotchaporn , Namdamrassiri Benyapa , Sriket Chodsana , Hoque Md. Sazedul , Karnjanapratum Supatra , Narkthewan Patcharaporn
Published: January 2025

This study investigates the development of a low-sodium seasoning powder using Chaya (Cnidoscolus chayamansa), popularly known as Mexican spinach, by substituting sodium chloride (NaCl) with potassium chloride (KCl) at various ratios. The antioxidant capabilities of dried Chaya leaves, dried at 60°C for five hours, were tested using 2,2-Diphenyl-1-picrylhydrazyl (DPPH), Ferric reducing antioxidant power (FRAP), and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic) acid (ABTS) techniques, demonstrating excellent free radical scavenging activity and making it suitable for low sodium seasoning compositions. The substitution of 25% KCl was the most favored option, as it effectively balanced flavor and health advantages without causing noticeable changes in appearance, color, and aroma. This recipe successfully reduced the sodium content to 1171 mg/100 g while maintaining Chaya’s original nutritional values, which include 23.57 g/100 g of protein, 4.77 g/100 g of fats, and 54.12 g/100 g of carbohydrates, as well as dietary fibers. Additionally, the formulation demonstrated physicochemical stability, as indicated by an ash content of 14.00 g/100 g, moisture content of 3.51 g/100g, and a total energy of 353.69 kcal/100 g. The safety of this new seasoning is validated by its microbiological quality, which is indicated by a total bacterial count of 2.6×104 cfu/g and the absence of mold and yeast. This emphasizes the potential of the seasoning to promote healthy dietary choices by reducing sodium intake without affecting sensory appeal.
Heavy Metals Assessment in Selected Leafy Vegetables from Selangor, Malaysia
Authors: Sian Nee See , Pak Dek Mohd Sabri , Sanny Maimunah , Shukri Radhiah , Ramli Nurul Shazini
Published: January 2025

Leafy vegetables may contain heavy metals that possess negative impacts on human health. However, no structured monitoring has been available so far in terms of the heavy metal content of vegetables sold in markets across the country. Thus, the present study aimed to investigate heavy metals concentration [aluminium (Al), cadmium (Cd), chromium (Cr), copper (Cu), iron (Fe) and lead (Pb)] in selected leafy vegetables (Brassica oleracea subsp. capitata L., Brassica juncea Czern., Spinacia oleracea L., and Brassica rapa var. chinensis) from Selangor wholesale wet markets using inductively coupled plasma–optical emission spectrometry. Potential health risks linked to their consumption were assessed by estimating daily intake of toxic metals (EDI) and calculating both cancer and non-cancer risks, including hazard index and target hazard quotient (THQ). Results showed that the average concentrations of Al and Fe in vegetable samples were within the permissible limits, with the greatest amount of Al found in spinach (41.37 mg/kg). The mean levels of Fe in cabbage, mustard, spinach, and pak choi were 6.30 ± 5.78, 4.12 ± 1.84, 13.59 ± 4.73, and 4.14 ± 0.31 mg/kg, respectively. However, Cd, Cr, Cu, and Pb were undetected in all samples. THQ values derived from the EDI of heavy metals were discovered to be less than one, suggesting a low likelihood of adverse health effects. In conclusion, although leafy vegetables present negligible health risks, consumers should vary their vegetable intake to prevent long-term health effects.
Effects of Different Extraction Methods on Yield, Polyunsaturated Fatty Acids, Antioxidants, and Stability Improvement of Chia Seed Oil: A Review
Authors: Ishak Izzreen , Coorey Ranil , Abd Ghani Maaruf , Chin Ping Tan , Saari Nazamid , Hussain Norhayati
Published: January 2025

There has been an increasing trend in the use of chia seed oil (CSO) rich in polyunsaturated fatty acids (PUFA), mainly α-linolenic and linoleic acids, accompanied by antioxidants like tocopherols, phytosterols, carotenoids and polyphenols, which may benefit to human health. Various conventional (solvent and mechanical pressing) and alternative extractions (supercritical fluid extraction using carbon dioxide and ultrasound-assisted method) have been utilised to extract oil from chia seed based on selected conditions and types of solvent, which affect the oil yield and nutritional composition. Alternative extractions like ultrasound-assisted with solvent (time: 40 min, temperature: 50°C and solvent-to-seed ratio: 12 ml of ethyl acetate/g of chia seed) and supercritical fluid extraction (SFE) using carbon dioxide enriched with 10% acetone (time: 300 min, temperature: 70°C and pressure: 280 bar) can be applied to improve the amount of oil (up to 27.1% and 33.9% for ultrasound-assisted with solvent and SFE, respectively) and PUFA extracted from the chia seed. SFE is recommended as a highly desirable alternative to traditional methods (Soxhlet and pressing) for extracting tocopherol and phytosterol from CSO. Incorporating acetone with SFE could enhance the number of polyphenols and carotenoids in CSO compared to pure supercritical carbon dioxide. However, CSO is highly susceptible to oxidation due to its high concentration of PUFA (more than 80%). Recent research on the nutritional qualities of CSO has explored the impact of improvement techniques to prevent loss of nutritional quality. Therefore, natural antioxidants and blends of vegetable oils have been applied to improve CSO’s oxidative stability and shelf life.
Determination of the Pathogenicity of the Variant UPM 1432/2019 IBDV in SPF Chicken Eggs and Chicken Fibroblast Cell Line
Authors: Mansour Ali Youssif , Omar Abdul Rahman , Mohd Hair Bejo  , Alitheen Noorjahan Banu , Mat Isa Nurulfiza
Published: January 2025

The infectious bursal disease virus (IBDV) is a nuisance to chicken productivity in the global poultry industry due to its high pathogenicity. In this study, the pathogenicity of the UPM 1432/2019 variant was evaluated using specific pathogen-free (SPF) chicken eggs and fibroblast cell lines. This viral strain was isolated from chickens displaying symptoms of watery diarrhoea and ruffled feathers. Following inoculation, the SPF chicken eggs, and cell lines were meticulously monitored for indicators of viral replication and the onset of cytopathic effects (CPE). The results showed that the virus could replicate in the SPF eggs and cell lines due to the presence of CPE in some cells. In addition, virus-induced weight loss in infected embryonated chicken eggs was evaluated. The UPM 1432/2019 and UPM 1219/2019 strains demonstrated similar mortality rates and CPE features. These findings indicate that the UPM 1432/2019 variant is pathogenic in SPF chicken eggs and fibroblast cell lines. Furthermore, the new UPM 1432/2019 variant caused IBD with pathogenic characteristics similar to the traditional UPM 1219/2019 variant. The emergence of the UPM 1432/2019 variant poses a risk to the economy and poultry production and is potentially resistant to the existing bursal disease vaccines. Consequently, the UPM 1432/2019 variant may significantly contribute to economic losses for chicken farm operators. Moreover, this study provides essential information on the potential virulence of the UPM 1432/2019 variant of IBDV and its potential impact on the poultry industry.
Consumer perception and acceptance of plant-based meat substitutes
Authors: Predanócyová Kristína , Kubicová Ľubica , Pindešová Diana
Published: January 2025

Nowadays, the meat market is affected by the changes in consumer lifestyles related to the health, sustainability, and environment as well as population growth and the increasing meat demand. In the following years, meat production can be replaced partially by production of meat substitutes. The aim of the paper is to point out the consumer perception and acceptance of plant-based meat substitutes, as well as to identify key motives and barriers for their consumption. For fulfilment the aim a consumer survey was carried out in Slovakia on a sample of 733 respondents. Using statistical methods, differences in consumer attitudes towards plant-based meat substitutes were examined in three identified segments, namely meat consumers, meat and also meat substitutes consumers, meat substitutes consumers. The first segment includes consumers who think that it is not possible to replace meat with plant-based meat substitutes. However, consumers expect that consumption of plant-based meat substitutes to be moral, ecological, sustainable, safe and healthy. These consumers consider similarity to meat in taste, smell and appearance as key motives for consumption and they state that the main reasons for consumption are the health aspect, taste and environmental protection, and the main barriers are the habit of meat and the fear of lack of appetite. Consumers from the second segment perceive plant-based meat substitutes as an acceptable alternative for the future, and they expect consumption to be moral, ecological, safe and healthy. Currently, most consumers already consume plant-based meat substitutes or assume their consumption in the future, and the key reasons are health, environment and taste. The key motive for higher consumption is consumer awareness related to health, the impact on the environment and the production process. The last segment includes consumer who consume plant-based meat substitutes due to environmental protection, their lifestyle and health aspects and perceive them as a suitable alternative. Consumers consider their consumption to be moral and nutritious and higher consumption will be achieved by increased consumer awareness. Based on the results of the study and the situation on the meat market, it is desirable that Slovak consumers gradually should become informed about alternative diet and accept the possibility of consuming plant-based meat substitutes. The research paper provides a new perspective on the consumer acceptance and consumption of plant-based meat substitutes, divided into three segments regarding current eating habits of consumers, which can fill the scientific research gap because this issue has not yet been examined in Slovakia. The results of the study provide valuable information to food companies in the creation of marketing strategies and policy makers in improving food policy and supporting the public health.
Does the Adoption of TSA as a Central Electronic Revenue Collection Really the Solution? Evidence from Nigeria
Authors: Ekekwe Ezinwanne , Ikpegbu Daniel , Okeke Augustine , Ezeani Kingsley
Published: January 2025

The crave for technological device or innovation to forestall, mitigate and
resuscitate the economic challenges encountered by developing
countries in the world is laudable and impressive. However, the growing
urge for these technologies raises this question- is technology a prerogative for
accountability? Drawing from a case study research design, this study evaluates
the impact of such technologically driven idea towards countries economy in
corrupt societies. The findings highlight that the failure to check and strike a
balance between the new digital idea and the traditional system makes the whole
process more vulnerable to corrupt practices. These observations are not meant
to discourage the use of 'treasury single account' (TSA) or other technologically
innovative ideas like 'integrated personnel payroll information system' (IPPIS)
that could serve as a solution towards harnessing the economy of Nigeria.
Therefore, the analysis draws attention to the importance of more careful
assessments of the problems, as well as the benefits of such innovative ideas – in
attempt to achieve the set objectives.
Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue
Authors: Yngve Erik , Ingvast Sofie , Korsgren Olle , Yu Di
Published: January 2025

Background: Oncolytic viruses are promising tools for immune stimulatory gene therapy of cancer, but their clinical effect on solid tumors have so far been limited. Transduction of the target tumor cells is limited by both extracellular matrix that blocks viral spread within the solid tumor tissue and electrostatic forces that inhibit virus from binding its entry receptor on the cell surface. The enzymes hyaluronidase and collagenase and the polycations diethylaminoethyl (DEAE)-dextran, branched Polyethylenimine (PEI) and protamine sulfate have previously shown potential to improve gene transfer in different forms of viral gene therapy, since they may help the virus to overcome these barriers. In this study, we compared the transduction-enhancing potential of these substances when used as vehicles for adenoviral transduction in solid tumor tissue.
Methods: Subcutaneous tumors of pancreatic ductal adenocarcinoma were established in mice and treated with a mix of adenoviral vector Adf35(GFP-Luc) and either one of the selected vehicles. Transduction efficacy was determined by quantification of the viral transgene expression level using live imaging.
Results: Addition of hyaluronidase tripled the transgene expression of Adf35(GFP-Luc) when compared to virus alone. No such positive effect was seen for the other tested vehicles.
Conclusions: Out of the tested candidates, hyaluronidase showed the best potential to facilitate viral spread in tumor tissue and transduction of tumor cells. Therefore, hyaluronidase may be used as vehicle to improve clinical efficacy of oncolytic virotherapies.
STATISTICAL ANALYSIS OF DENGUE CASES IN THE MÉDIO PARAÍBA DO SUL REGION, RJ
Authors: SEIXAS Gabriela Lorrane , RODRIGUES Filipe da Costa , ARAÚJO Marco Antonio Pereira , MENDONÇA Paloma Martins
Published: January 2025

Dengue is an arbovirus transmitted to humans through the bite of the female Aedes aegypti mosquito. The clinical presentation ranges from a nonspecific and benign viral syndrome to a severe and fatal condition. The objective of this study was to analyze data on dengue cases from 2019 and 2022 in the Médio Paraíba do Sul Region using Minitab® software. Statistical analysis revealed a difference in the average number of cases, with a higher concentration in 2019, attributed to factors such as the Covid-19 pandemic, which may have contributed to underreporting in 2022 due to the restructuring of epidemiological surveillance actions. The research concludes that new public policies and investigations are necessary for the effective control of dengue, a reemerging disease with high morbidity and mortality, reinforcing the importance of accurate case reporting to support health policies.
RE-APPRAISAL OF THE PROCEDURE OF QUALITATIVE INDUCED POLARISATION VALIDATION OF GROUNDWATER PROSPECTS AT THE SOUTHERN PHASE II DEVELOPMENT, GIDAN KWANO CAMPUS, MINNA, NIGERIA
Authors: JONAH Sunday Adole
Published: January 2025

It is a desired situation if complementary geophysical data is available to aid deductions made based on analysis of a body of core data, like a corpus of vertical electrical soundings, say. At the southern Phase II Development of the Gidan Kwano Campus, Federal University of Technology, Minna, complementary induced polarisation data was acquired in tandem with vertical electrical sounding data in a dedicated survey program. The approach of the initial qualitative induced polarisation validation of the groundwater-resource deductions based on the interpretation of the sounding data fixed the number of groundwater prospects at 57 out of a total of circa 309 stations surveyed. This study concerns adopting a different course of qualitative induced polarisation validation that was de-emphasized in the earlier study and observing if there are disparities in the deductive outcomes regarding assured groundwater locations at the study area; this approach emphasizes strong bearings on “zero-weighted” induced polarisation values in the correlation regime. Thus, the number of groundwater prospects is now fixed at 47 post-induced polarisation validation from a list of soundings tagged as 89 prospect locations out of a total of circa 309 stations surveyed. There are circa 19 points that are tagged as coincident points in the earlier study and in the one herein. In order to solve the vexing groundwater problem plaguing the developed tranche of the Gidan Kwano Campus, it is recommended that the University adopts the idea of a multi-well single-output water scheme whence the survey locations flagged herein for their characteristic and comparatively deep-seated fractures should be exploited for their groundwater resource. Any planned drilling regime based on the recommendation herein must be guided by the full-length paper that is the work herein so as to pinpoint those locations where induced polarisation-data regimes actually point to very dependable groundwater exploitable potentials.
QUANTITATIVE ASSESSMENT OF ENVIRONMENTAL LICENSING IN NON-LICENSING MUNICIPALITIES OF RIO DE JANEIRO: A COMPARATIVE STUDY BETWEEN 2022 AND 2023.
Authors: AMARAL Monique da Silva , BRASIL Felipe da Costa , CAMARA Paulo Wilton da Luz , ARAÚJO Marco Antônio Pereira , PEREIRA Cristiane de Souza Siqueira
Published: January 2025

Human development generates both positive and negative environmental impacts. Negative impacts include soil, air, and water pollution, as well as ecosystem degradation, while positive impacts involve job creation, economic and technological development, and sustainable practices. Environmental licensing is an essential administrative procedure to ensure that potentially polluting activities are conducted in a way that harmonizes economic development with environmental preservation. This study aims to analyze the licenses issued by the State Institute for the Environment of Rio de Janeiro (INEA) in the years 2022 and 2023 across nineteen non-licensing municipalities, seeking to understand the challenges they face. The research is based on data collected through the transparency platform "Ambiente +" and analysis using Minitab software. The results of this study highlight the need to strengthen the institutional and technical capacity of non-licensing municipalities, promoting awareness of the importance of environmental licensing and providing the necessary support so that these municipalities can fully assume their responsibilities in local environmental management.´
ANALYSIS OF USED COOKING OIL COLLECTION IN VASSOURAS - RJ (2021-2023)
Authors: CONFORT Sandra Regina Alves , PESSOA Fernando Luiz Pellegrini , ARAÚJO Marco Antônio Pereira , PEREIRA Cristiane Souza Siqueira
Published: January 2025

Improper disposal of used cooking oil represents a significant environmental challenge, contributing to the pollution of water resources and escalating water treatment costs. The recycling of waste oil aligns with several Sustainable Development Goals (SDGs) articulated in the commitments established by the 2030 Agenda during the United Nations Summit in 2015. The primary objective of this study was to conduct a statistical analysis of waste oil collection in Vassouras, RJ, over the period from 2021 to 2023. The descriptive statistical analysis was performed using the Minitab software to examine the normality of the monthly quantity using the Anderson-Darling method, homogeneity of variances by Levene's test, and comparison of the means of the volume of oil collected by Analysis of Variance (ANOVA). The results obtained indicated a p-value of 0.123 in the Anderson-Darling normality test, a p-value of 0.425 in the Levene test, and a p-value of 0.592 in the ANOVA test. These values suggest that, in the last three years, the collection of residual oil has remained stable, without the presence of extreme patterns or severe asymmetries, presenting minimal monthly variations at a significance level of 5%. On average, 1,012.97 liters/month were collected, equating to approximately 34 mL per inhabitant, a marginal figure when evaluating the total population of the city, which is approximately 34,000 inhabitants. The expansion of the network of voluntary delivery points, the training of environmental agents, and the encouragement of reverse logistics initiatives can also contribute to the increase in the volume collected and the proper disposal of this waste. Additional awareness-raising initiatives by governmental bodies, corporations, and educational institutions be implemented to enhance public awareness and improve the collection of this waste, thereby conserving water resources.
STATISTICAL ANALYSIS OF BIOGAS PRODUCTION BETWEEN 2022 AND 2023 IN THE STATE OF RIO DE JANEIRO
Authors: GUIMARÃES Fabio Luís Alvarenga , ARAÚJO Marco Antônio Pereira , RIBEIRO Sandro Pereira
Published: January 2025

According to Cibiogás and the Energy Research Company, biomethane gas production is expanding in Brazil. It is estimated that the production value has increased by 87% over the past 10 years, with the largest production volume associated with the sanitation sector (74%), notably with landfills responsible for 96% of biogas production in this category. According to data from the National Petroleum Agency (ANP), in the years 2022 and 2023, there was an increase in biomethane gas production in the northeast and southeast regions. This study investigates the impact of increased biomethane gas production capacity in 2022 and 2023 specifically in the state of Rio de Janeiro. In 2022, a new government cycle began, so using Minitab software, we conducted a statistical analysis to determine if there were significant changes in biomethane production in landfills in the state of Rio de Janeiro, given recent developments in Brazil's sanitation sector.
THE ROLE OF PROGESTERONE METABOLITES ON THE PROLIFERATIVE-APOPTOTIC BALANCE OF HUMAN OVARIAN CARCINOMA-DERIVED CELL LINES
Authors: Cáceres Antonella Rosario Ramona , Cardone Daniela Alejandra , Cerdeño Marisa Roig , Sanhueza María de los Ángeles , Laconi Myriam Raquel
Published: January 2025

Ovarian cancer is the most lethal gynecologic malignancy and the fifth leading cause of cancer death in women. Progesterone can have different effects depending on the hormonal conditions or the physiological environment in which it is administered. Its effect varies depending on the hormonal concentrations present in the body, since these can modify the body's response to the drug , particularly in cancer. P4 is metabolized into two groups: the 5?-pregnans, including allopregnanolone (ALLO), and the 4-pregnans, such as 3?-dihydroprogesterone (3?HP) and 20?-dihydroprogesterone (20?HP). Previous studies in the breast suggest that 5?-pregnans promote tumor growth, whereas 4-pregnans have antitumorigenic effects. This study aimed to evaluate the effects of these metabolites on the proliferation-apoptosis balance in the human ovarian cancer cell lines IGROV-1 and SKOV-3. Both cell lines were cultured and treated with increasing concentrations of ALLO, 3?HP, and 20?HP. Proliferation was measured by MTT assay, and apoptosis was assessed by immunocytochemistry and flow cytometry. ALLO significantly increased cell proliferation in the IGROV-1 cell line, whereas no effect was observed in SKOV-3. In contrast, 3?HP and 20?HP decreased cell proliferation in both cell lines. In addition, 20?HP increased the expression of cleaved caspase-3 in IGROV-1, indicating an apoptotic effect. Flow cytometry showed that 4-pregnane derivatives increased apoptotic effect. This study provides new insights into the role of P4 derivatives in ovarian epithelial carcinoma-derived cells. It lays the groundwork for future research on signaling pathways and molecular mechanisms to elucidate the physiological role of these molecules in contributing to the development of new diagnostic and therapeutic approaches.
NEUROMODULATORY EFFECTS OF ESTRADIOL AND PROGESTERONE ON KETAMINE'S ACTION IN FEMALE RAT BRAIN
Authors: GONZALEZ Natalia Belén , RAMIREZ Paloma Lucía , VARGAS HUNGER Esther Berenice , CABRERA Ricardo Jorge
Published: January 2025

Ketamine-induced psychotic episodes with hallucinations and sensory dissociation when abused. In rats, prolonged intraperitoneal ketamine (K) administration increases locomotor activity. Neuroactive steroids modulate responses to such drugs. This study aimed to investigate ketamine-induced neuroadaptive effects and neuromodulatory phenomena from Estradiol (E2) and Progesterone (P4) in female rats. Female rat ovariectomies (OVX) were performed, followed by open field behavioral tests to assess locomotor activity (LA), which were analyzed using the EthoWatcher software. Significant LA increases were observed in control EP and K groups vs. C. E2 and P4 further raised LA in sensitized OVX animals. The results demonstrate that E2 and P4 supplementation enhances potentiation, indicating genomic and non-genomic interactions, leading to positive neuroadaptive plasticity with K.
GLOBAL WARMING: "BEYOND THE ICE: PUBLIC AND SCIENTIFIC INSIGHTS INTO POLAR MELTING AND SEA-LEVEL RISE"
Authors: MEDINA Ariel Leonel , AGÜERO Josefina
Published: January 2025

In this article, we review the attention and focus received by the world's population on polar melting, employing five key terms (permafrost, sea level, moulin glacier, glacial melt, glacier melt, glacier melt) in three search engines: Google, Google Scholar, and Google Trends. Through an analysis of scientific articles and general interest notes, we explored search trends and public interest, identifying patterns and the extent of coverage on the impact of polar melting on global warming.
THERMAL REACTIONS OF 2,2-DIOXO-1H,3H-PYRROLO[1,2-C]THIAZOLES STUDIED FROM GREEN METRICS
Authors: PINILLA PEÑA Diana Carolina , SOARES María Isabel , PIERELLA Liliana Beatriz , PINHO E MELO Teresa María V. D. , PELÁEZ Walter José
Published: January 2025

The concept of Green Chemistry, introduced 25 years ago by the U.S. Environmental Protection Agency, aims to assess the sustainability of chemical processes. During this time, Dr. Barry Trost developed Atom Economy, which measures how "green" a reaction is using parameters such as Atom Economy (%AE), Mass Intensity (MI), and Reaction Mass Efficiency (RME). Recently, the focus has shifted to evaluating flash vacuum pyrolysis reactions under these principles. This study presents results from evaluating the thermal stability of 2,2-dioxo-1h,3h-pyrrolo[1,2-c]thiazoles, which are of pharmacological interest, through pyrolysis at temperatures between 200-275ºC. The results are compared with traditional yield values and complemented by assessments using multiparametric frameworks like EcoScale and Green Star, aiming to identify the environmental impact of these reactions. This comprehensive approach advances the sustainability of chemical processes, promoting more responsible practices in chemical research and application.
Effect of varying doses of Cisplatin on rat intestinal cell apoptosis
Authors: Kumar P Uday , B Vijayalakshmi , S Kalyanasundaram , M Raghunath , B Sesikeran
Published: January 2025

The purpose of this study was to (a) determine the dosage of cisplatin required to induce intestinal epithelial  cell apoptosis, without causing lethality or necrosis and (b) to assess the biochemical changes in intestinal  mucosa with different doses of cisplatin administration. A total of 9 WNIN weanling male rats were divided  into three groups (n=3). Groups I and II rats were administered low and high doses of cisplatin intraperitoneally  (3 and 12 mg/kg body weight) for three weeks, based on computation from human dose while control rats  were administered saline intraperitoneally. Morphometric apoptotic counts increased significantly in both  villus and crypt regions of the jejunum in animals of group I but not in animals of group II as compared  to control. These changes in apoptotic index correlated with enhanced caspase-3 activity and DNA ladder  pattern studies. Increased cell death also resulted in loss of functional integrity of the jejunal mucosa and these  events were linked to increased oxidative stress and altered antioxidant enzyme activities. A weekly dose of  3 mg cisplatin/kg body weight appeared to induce intestinal epithelial cell apoptosis in WNIN strain, without  causing mortality and could be used as a model for determining the therapeutic and cytoprotective potential of  novel test candidates.