bluuebunny/crossref_metadata_2025 huggingface dataset:
Saúde Mental Infantojuvenil: Desafios da Regionalização da Assistência no Brasil / Mental Health in Childhood and Adolescence: Challenges Due to the Regionalisation of Care in Brazil
Authors: Macedo João Paulo , Fontenele Mayara Gomes , Dimenstein Magda
Published: June 2018

Esse trabalho teve como foco a atenção psicossocial infantojuvenil no Brasil, a qual historicamente tem sido marcada pela prática da tutela e da institucionalização.Constatamos por meio de metodologia de cruzamento de informações acerca dos serviços voltados à essa população na RAPS, incluindo dados das regiões de saúde, que os mesmos são insuficientes e desigualmente distribuídos. Existem muitos vazios assistenciais no país, em todas as regiões. Essa situação pode ser atribuída à fatores políticos, deficiência na formação de recursos humanos especializados, problemas na proposta da regionalização em saúde, dentre outros. Destacamos, a necessidade de articulação entre os diversos níveis que compõem a atenção em saúde mental na RAPS, bem como com outros dispositivos do território na perspectiva da intersetorialidade e gestão territorial das necessidades em saúde mental de crianças e adolescentes.Palavras-chaves: Saúde Mental; Atenção Psicossocial Infantojuvenil; Regionalização; CAPSi.
Análise de Implicações: Uma Potência Problematizadora aos Pesquisadores Supostamente “Sabidos” / Analysis of Implications: A Problematizing Power to the Researchers Supposedly “Known”
Authors: Londero Mário Francis Petry , Soares Letícia Quarti
Published: June 2018

Este artigo tem por base uma pesquisa de conotação avaliativa, participativa e interventiva, realizada na região metropolitana de Porto Alegre, que investigou os processos de cuidado em Saúde Mental na Atenção Básica da rede de saúde pública. O estudo aqui tratado realizou um recorte dessa pesquisa, analisando os encontros ocorridos especificamente na capital, uma das seis participantes da intervenção, à luz da metodologia cartográfica. A proposta foi analisar as implicações dos pesquisadores sitiados neste campo da pesquisa maior, como foram os processos dialógicos entre pesquisadores, usuários, trabalhadores, familiares e gestores de saúde, e o que se produziu diante das problemáticas da rede e suas possíveis invenções para dar conta do cuidado em saúde mental na atenção básica. Vimos, ao longo do processo, o quanto o contato com um campo participativo produz um saber que problematiza e transforma os conhecimentos preestabelecidos pelos pesquisadores.Palavras-chave: Análise de Implicação; Saúde Mental; Atenção Básica; Pesquisa-Intervenção; Pesquisa Participativa.
Atenção psicossocial e atenção básica: a vida como ela é no território / Psychosocial care and primary care: life as territory in the field
Authors: Yasui Silvio , Luzio Cristina Amélia , Amarante Paulo
Published: June 2018

O presente ensaio tem por objetivo refletir sobre os termos Atenção Psicossocial e Atenção Básica como proposições que se apresentam como uma mudança de paradigma, articulando com o conceito de território que surge aqui como elemento comum aos dois campos, especialmente no que concerne a produção de cuidado que nele se faz e em rede. Esta perspectiva implica em um olhar para a diversidade social e cultural dos diferentes locais como um aspecto essencial para articular as ações de saúde e de saúde mental, no espaço onde a vida acontece como ela é, em sua plenitude. Implica, também, no caso da Atenção Psicossocial, em superar lógicas de exclusão e aniquilamento das diferenças que incidem sobre os nomeados “loucos”, e também, sobre todos que explicitam modos diversos de existir.Palavras-chave: Atenção Psicossocial; Atenção Básica; Território: Reforma Psiquiátrica; Reforma Sanitária.
SUSTAINABILITY AND TAILINGS MANAGEMENT IN THE MINING INDUSTRY: PASTE TECHNOLOGY
Authors: Yilmaz Erol , Yilmaz Elif
Published: June 2018

In this study, the basic principles of paste technology which has been implemented successfully in the mining industry for both waste volume reduction and environmental impact reduction were investigated. In the past two decades, paste technology has progressed from a research-based mine backfill idea to a widely accepted and cost-effective fill system with the potential to totally change the approach tailings are disposed on the surface. Application of paste tailings for modern mines was shown experimentally by laboratory and field testing, focusing on intrinsic (e.g., tailings, cement and mix water properties) and extrinsic (e.g., in situ mixing, placement and curing conditions) parameters. Results indicate that use of paste tailings as backfilling and disposal in the mining industry as an innovative and environmentally sound system can guarantee operational continuity by reducing environmental (e.g., tailings dam failure, acidic water formation) and financial concerns over the mine’s life. Finally, paste technology enables mining operators to better manage their problematic tailings produced in the mineral processing plants.
Ion/surface collisions: an alternative to gas-phase collisional activation in mass spectrometry
Authors: Ast Teodor
Published: June 2018

1. Introduction 2. Instrumentation 3. Surface-induced dissociation 4. Solid
surfaces 5. Isomeric ion distinction 6. Conclusion
NMR analysis of 2-(2’,3’-dihydro-1’H-inden-1’-yl)-1H-indene
Authors: Jovanovic Jovan , Spiteller Michael , Spiteller Peter
Published: June 2018

1H, 13Cand two dimensional NMR analyses were applied to determine the NMR
parameters of 2-(2?,3?-dihydro-1?H-inden-1?-yl)-1H-indene. The chemical
shifts of all the H- and C-atoms, as well as the appropriate coupling
constants were determined and the complete NMR resonance assignments of the
molecule are given. The predicted patterns of the four different H atoms of
the two methylene groups of the indane structural element coincided
completely with the complex patterns in the NMR spectra.
On the kinetics of the hydrogen evolution reaction on zinc in sulfate solutions
Authors: Trisovic T. , Gajic-Krstajic Lj. , Krstajic N. , Vojnovic M.
Published: June 2018

The kinetics and mechanism of the hydrogen evolution reaction (her) were
studied on zinc in 1.0 mol dm-3 Na2SO4 at 298 K, in the pH range 4.4 - 10. It
was found that a combination of classical potentiostatic steady-state
voltammetry (PSV) and electrochemical impedance spectroscopy (EIS) can help
to elucidate dilemmas concerning the mechanism of this reaction. Thus, over
the whole potential region, the reaction path of the her on zinc cannot be
presented by the classical Volmer-Tafel-Heyrovsky route. It was found that
the very complex S-shape of the polarization curves could be explained by
two parallel reaction mechanisms for the her. The first reaction mechanism
is a consecutive combination of three steps, in which the surface zinc oxide
plays an active role in the her, and second reaction mechanism is a
consecutive combination of a Volmer step, followed by a Heyrovsky step. The
second mechanism is dominant in the more negative potential region where the
active sites for the her are metallic zinc.
A time effect in the early stages of a surface oxidation of a Pt(111) plane in alkaline solution
Authors: Tripkovic A.V. , Popovic K.Dj. , Lovic J.D.
Published: June 2018

A time effect in the early stages of surface oxidation of a Pt(111) plane in
0.1M NaOH solution was studied by examining the reduction parts of the j/E
profile recorded after holding the potential for various times at several
values at the end of anodic-going sweeps. The processes associated with the
two peaks, which appear in the anodic part of the voltammogram, are assigned
to the early stages of a surface oxidation. Two OHad states are suggested
based on the existence of reversibly or weakly bound OHad species and
irreversibly or strongly bound OHad species. The reversibly bound OHad species
are involved in the ?normal? structure of the butterfly peak, while the
irreversibly adsorbed OHad species can be obtained only by the slow
diffusion of a part of the initially electrosorbed OH species from sites
with low to sites with higher binding energies. The irreversibly reducedOHad
species cannot be completely removed from the surface causing, therefore,
some permanent transformation of the initial state of the surface. This kind
of species was not detected in the area of the second oxidation peak. The
phenomena observed in the reduction part of the j/E profile induced by a
time effect in the second peak could be associated with a place-exchange
mechanism between oxygen containing species, whatever they are, and the
platinum surface.
Layer formation by 1,7-diphosphono-heptane
Authors: Póczik P. , Felhősi I. , Telegdi J. , Kalaji M. , Kálmán E.
Published: June 2018

Surface modification of polycrystalline ARMCO iron and an Fe(110) single
crystal was performed using a solution of 1,7-diphosphono-heptane (DPH). The
changes of the surface properties were studied by subtractively normalised
interfacial Fourier transform infrared spectroscopy (SNIFTIRS), scanning
tunneling microscopy (STM) and electrochemical impedance spectroscopy (EIS).
The immersion of the surfaces into DPH solution resulted in a build up of an
ordered thin multimolecular layer after a few hours of continuous
adsorption. The orientation of the DPH molecules was influenced by the
supporting electrolyte and the electrode potential. The treatment in the
absence of oxygen resulted in a lower corrosion protection effect compared
to diphosphonate layer formation in an atmospheric environment.
Current oscillations of iron in p-toluenesulfonic acid
Authors: Cui Haitao , Chen Shenhao , Zhao Shiyong , Wang Chao
Published: June 2018

The periodic current oscillations of an iron electrode in p-toluenesulfonic
acid (PTSA) solutions were investigated by cyclic volatammetry and
potentiostatic polarization. The Fe/PTSA system is a new electrochemical
oscillator and shows some interesting phenomena. The oscillations are
ascribed to the alternate buildup and breakdown of Fe(OH)2 and Fe3O4 films.
Characterization and corrosion properties of electrodeposited Ni-W alloys
Authors: Obradovic M. , Stevanovic J. , Despic A. , Stevanovic R. , Stoch J.
Published: June 2018

Ni-W alloys electrodeposited from citrate solution consist of three different
phases, which are all present in high W-content alloys: a solid solution of
W in a Ni matrix; an intermetallic compound Ni4W, as well as another solid
solution of Win Ni with a W content higher than 20 mol.%. XPS analysis revealed
that the alloys were covered with a surface layer of complex structure
containing the pure metals Ni and W, Ni(OH)2 andWO3, on the very surface as
well as some partially reduced oxideWO2.72 (most probably a solid solution
of WO2.72 in Ni) and tungsten carbide in the layer underneath. It is highly
likely that some of the oxide species in the layer act as intermediates in
the cathodic deposition process. Identifying these species should be the
clue to a more detailed understanding of the mechanism of induced deposition
of W than has been achieved so far. Corrosion of Ni-W alloys in sulfuric acid
solution at OCP, occurs by the preferential dissolution of nickel from the
surface layer. The longer the corrosion process lasts, the more the surface
behaves like pure W. The lowest initial corrosion rates were recorded with
alloys rich in W, but after aging at OCP the lowest corrosion c.d. was found
for the Ni-W alloy with the most homogenous phase structure, consisting of
the solid solution only.
A study of the morphological aspects of the indium electrorefining process
Authors: Hadzi-Jordanov Svetomir , Dimitrov Aleksandar , Paunovic Perica , Slavkov Dragan
Published: June 2018

The cathodic deposition of In was performed under conditions suitable for
electrorefining purposes. The main goal of the study was: i) to determine
the possibilities for In ultrapurification through multiple electrorefining
with controlled parameters and ii) to study the regularities of the
morphology of the In deposit as influenced by the electrodeposition
conditions. Without application of special high purity techniques, it was
possible to obtain an In purity level of 99.997 %, by repeating the refining
procedure in a set of modular electrolysis cells with forced electrolyte
circulation and applying modified current regimes. Irregular (non
planparallel) migration of indium from the anode to the cathode and vice
versa, as well as dendrite formation at the edges of the electrode prevented
further repetition necessary for the achievment of higher purification
levels. This provoked the need to study the morphology of the In-deposits.
The phenomena and some regularities of In nucleation and grain growth, as
influenced by the applied overpotential and quantity of current passed
through the cell, were studied. Electrodeposition was performed onto a
stationary Pt-electrode from amixed sulfate-chloride solution. SEM with
magnification up to 1000 x was used to identify the morphology of the
deposits. Granular grains were dominant at over potentials of 85 and 110 mV,
while at 160 and 185 mV, needle-like and non branched dendrites were visible.
The deposit became less compact as its thickness advanced. The apparent
thickness of the In layer increased from 20-25 to 320-380 ?m when the amount
of charge was increased from 1 to 10 mA h cm-2.
The effect of particle structure on apparent density of electrolytic copper powder
Authors: Pavlovic M.G. , Pavlovic Lj.J. , Ivanovic E.R. , Radmilovic V. , Popov K.I.
Published: June 2018

The quantitative microstructural analysis and the sieve analysis of copper
powder as well as the scanning electron microscopy analysis of the copper
powders particles were performed. It was found that the structure of the
copper powder particles determines the apparent density of copper powder. The
powder particles from the same fractions of different powders occupy
approximately the same volume, but the structure of metallic copper is very
different. This causes the difference in apparent densities of copper powder
obtained under different conditions. The more dendritic is the structure of
powder particles the smaller is the apparent density of copper powder.
A Randomized Controlled Trial Comparing Efficacy and Safety of Insulin Glargine 300 Units/mL Versus 100 Units/mL in Older People With Type 2 Diabetes: Results From the SENIOR Study
Authors: Ritzel Robert , Harris Stewart B. , Baron Helen , Florez Hermes , Roussel Ronan , Espinasse Melanie , Muehlen-Bartmer Isabel , Zhang Nianxian , Bertolini Monica , Brulle-Wohlhueter Claire , Munshi Medha , Bolli Geremia B.
Published: June 2018

OBJECTIVE

SENIOR compared the efficacy and safety of insulin glargine 300 units/mL (Gla-300) with glargine 100 units/mL (Gla-100) in older people (≥65 years old) with type 2 diabetes.

RESEARCH DESIGN AND METHODS

SENIOR was an open-label, two-arm, parallel-group, multicenter phase 3b trial designed to enroll ∼20% of participants aged ≥75 years. Participants were randomized 1:1 to Gla-300 or Gla-100, titrated to a fasting self-monitored plasma glucose of 5.0–7.2 mmol/L (90–130 mg/dL).

RESULTS

In total, 1,014 participants were randomized (mean age: 71 years). Comparable reductions in HbA1c were observed from baseline to week 26 for Gla-300 (−0.89%) and Gla-100 (−0.91%) in the overall population (least squares mean difference: 0.02% [95% CI −0.092 to 0.129]) and for participants aged ≥75 years (−0.11% [−0.330 to 0.106]). Incidence and rates of confirmed (≤3.9 mmol/L [≤70 mg/dL]) or severe hypoglycemia events were low and similar between both treatment groups, with lower rates of documented symptomatic hypoglycemia with Gla-300. The lower risk of hypoglycemia with Gla-300 versus Gla-100 was more apparent in the subgroup aged ≥75 years versus the overall population. Significantly lower annualized rates of documented symptomatic (≤3.9 mmol/L [≤70 mg/dL]) hypoglycemia were observed (Gla-300: 1.12; Gla-100: 2.71; rate ratio: 0.45 [95% CI 0.25–0.83]).

CONCLUSIONS

Efficacy and safety of Gla-300 was demonstrated in older people (≥65 years of age) with type 2 diabetes, with comparable reductions in HbA1c and similarly low or lower risk of documented symptomatic hypoglycemia versus Gla-100. A significant benefit in hypoglycemia reduction was seen in participants aged ≥75 years.
Effects of pulse parameters on porosity rate and flow characteristics of molten pool in pulsed laser welding
Authors: Shen Xianfeng , Zhao Shuming , Teng Wenhua , He Wenpei
Published: June 2018

Flow behavior determines the formation and evolution of porosity and other defects in laser welding, but the existing investigations of liquidity of molten pool are restricted by qualitative analysis methods, so it is of great significance to quantitatively characterize the flow patterns and flow characteristics of the pulsed laser welding for understanding the porosity suppression mechanism. A series of welding experiments was carried out by using 1.5 kW slab CO2 laser under a variety of pulse parameters, and the images of molten pool and keyhole were captured by using a high-speed camera during welding. Porosity rate was also obtained by image processing of x-ray inspection of weld joints. The flow characteristics of molten pools including speed and vortices from these images were extracted and analyzed quantitatively. Effects of different pulse frequency and duty ratios on penetration depth, weld width, and flow characteristics of the molten pool were investigated and compared with each other. A three-stage flow pattern of molten pool for pulse laser welding and the respective characteristics of each stage were revealed. The analysis result shows that the velocity at the starting time in a pulse impact phase is about three times of that in the steady-state phase and the primary mechanism for suppression of pores lies in the impact and stirring on molten pool in pulse laser welding. The other suppression mechanisms of pores for welding joints are also discussed.
Cellular automaton modeling for dendritic growth during laser beam welding solidification process
Authors: Geng Shaoning , Jiang Ping , Ai Yuewei , Chen Rong , Cao LongChao , Han Chu , Liu Wei , Liu Yang
Published: June 2018

A modified non-equilibrium cellular automaton (CA) model is proposed to simulate the dendrite growth along the fusion boundary under transient conditions during the solidification process of laser beam welding (LBW) pool. The main non-equilibrium solidification effects, including solute trapping, deviation of the liquidus line slope, and kinetic undercooling, are taken into consideration in this modified CA model. The evolution of dendrite morphology, concentration field, and velocity field was investigated. Four growth periods, i.e., the initial stable period, the instability period, the competitive growth period, and the short-term stable period, were observed during the solidification process of LBW pool. The dendrite growth patterns were different in these periods due to the transient solidification conditions. The solute distribution predicted by this modified CA model showed similar trends to that predicted by the previous phase field model. The dendrite tip velocity was significantly influenced by the thermal undercooling and constitutional undercooling in the LBW pool, and the tip velocity field can be divided into three stages, i.e., the planar growth stage, competitive stage, and short-term steady growth stage. In addition, further comparison between the simulated dendrite morphology and experimental dendrite morphology was performed. Results showed that the simulated morphology of dendrites agreed well with the experimental results. In particular, the primary dendrite arm spacing predicted by this model was in good agreement with that obtained from experiments.
Development of a joining gap control system for laser welding of zinc-coated steel sheets driven by process observation
Authors: Tenner Felix , Eschner Eric , Lutz Benjamin , Schmidt Michael
Published: June 2018

Laser deep penetration welding is already widely used in industry. However, a further increase in the number of possible applications is hindered by process instabilities leading to process defects for a variety of welding scenarios. To overcome this obstacle, sensing and control systems can be used to detect deviations in relevant process features and counteract by adjusting specific process parameters. Hence, there is a demand for process control systems to increase process stability and thus quality. To fulfil this demand, the development of a process sensor which acquires a broad variety of process emissions aiming to gain the full picture of the welding process is the ultimate goal. One way to find relevant relations between defects and process features is the correlation of a vast amount of data to a specific process defect. This approach is very time consuming and did often lead to unsatisfactory results if no correlations could be found between the sensor signals and the occurring process defects. For a more targeted development of a process control system, we propose the use of process observation methods with high temporal and spatial resolution. By the use of image and data analysis process features which characterize the evolution of defects can be extracted and the relation of specific factors to the characteristic process features can be found. Moreover, the mechanisms of the evolution of process defects can be observed and a tailored strategy can be designed to ensure a robust and reliable control of the process. By means of this strategy, sensors to measure the defect-related features, control interfaces, and actuators to change these features can be specifically chosen. In our paper, we illustrate these steps by the development of a joining gap control system for the laser welding of zinc-coated steel sheets in an overlap configuration. This process is a topic of current research and highly relevant for industrial application. In our study, we prove that the keyhole opening is a process feature which correlates with the joining gap between two sheets. Moreover, we show an exemplary design and build of a setup for adapting the joining gap with respect to the requirements given by the real-time applicability during the welding process. Afterwards, we merge sensor and actuator to a control system and validate it on different process situations. The validation shows that the gap can be measured and set during the laser welding process to reliably increase the process stability and quality. We conclude our paper with an outlook on how this system might be applied in an industrial environment.
Added value by hybrid additive manufacturing and advanced manufacturing approaches
Authors: Seidel André , Straubel Ariane , Finaske Thomas , Maiwald Tim , Polenz Stefan , Albert Maximilian , Näsström Jonas , Marquardt Axel , Riede Mirko , Lopez Elena , Brueckner Frank , Beyer Eckhard , Leyens Christoph
Published: June 2018

In order to lead to a competitive advantage, there is the need to carefully consider the pros and cons of state-of-the-art manufacturing techniques. This is frequently carried out in a competitive manner, but can also be done in a complementary way. This complementary approach is often used for the processing of difficult-to-machine materials with particular regard to high-tech parts or components. Hybrid machining processes or, more general, advanced machining processes can be brought to the point that the results would not be possible with the individual constituent processes in isolation [Hybrid Machining Processes Perspectives on Machining and Finishing (Springer International Publishing AG, 2016)]. Hence, the controlled interaction of process mechanisms and/or energy sources is frequently applied for a significant increase of the process performance [Advanced Machining Processes of Metallic Materials: Theory, Modelling, and Applications, 2nd ed. (2016)] and will be addressed within the present paper. A via electron beam melting manufactured gamma titanium aluminide nozzle is extended and adapted. This is done via hybrid laser metal deposition. The presented approach considers critical impacts like processing temperatures, temperature gradients, and solidification conditions with particular regard to crucial material properties like the phenomena of lamellar interface cracking [Laser-Based Manufacturing of Components using Materials with High Cracking Susceptibility (Laser Institute of America–LIA), pp. 586–592; Ti-2015: The 13th World Conference on Titanium, Symposium 5]. Furthermore, selected destructive and non-destructive testing is performed in order to prove the material properties. Finally, the results will be evaluated. This will also be done in the perspective of other applications.
Processing of ultra-hard materials with picosecond pulses: From research work to industrial applications
Authors: Stankevič Valdemar , Čermák Adam , Mikalauskas Saulius , Kožmín Pavel , Indrišiūnas Simonas , Račiukaitis Gediminas
Published: June 2018

The ultrashort laser processing of the cutting tools and cutting inserts from tungsten carbide, ceramic and metal composites (CERMET), and polycrystalline diamond materials was demonstrated, and the ablation rates of mentioned ultra-hard materials were evaluated for a laser wavelength of 1064 and 532 nm. The optimal processing throughput was estimated. Laser manufacturing was performed with the five-axis computer numerical control (CNC) machine and scanner for beam translation with the high speed and the ultrashort ∼12 ps pulse duration high repetition rate laser source. The systematic approach was implemented in an experimental variation of process parameters that play a significant role in processing quality. By varying the laser fluence, pulse overlap, and layers’ count, different material removing rates can be achieved from 300 nm/layer to ∼18 μm/layer. The submicrometer removing rate involves a high precision control of the structure depth. It was demonstrated that only by a minor change of the processing parameters, the surface roughness of the material could be minimized down to Ra < 300 nm. Rough and smooth processing can be combined to optimize the structure processing throughput.
At-a-glance - Lessons learned from launching the Manitoba Take-Home Naloxone Program
Authors: Bozat-Emre Songul , Marshall Shelley G. , Zhong Colin , Reimer Joss
Published: June 2018

The Government of Manitoba launched the provincial Take-Home Naloxone Program in
January 2017. By the end of September 2017, there were over 60 sites operating in
Manitoba. These sites distributed 765 kits to people at risk of opioid overdose, and 93 of
these kits were replacement kits used in overdose events. Most of these events occurred
among males (60.2%) and in a private residence (72.0%). Fentanyl and carfentanil
were the most common substances reported during overdose events. Take-Home
Naloxone Program data provide important information about the unique context of the
opioid crisis in Manitoba.
Évaluation des premiers effets du retrait des opioïdes à forte concentration sur les schémas de prescription en Ontario
Authors: Guan Qi , Khuu Wayne , Martins Diana , Tadrous Mina , Chiu Maria , Do Minh T. , Gomes Tara
Published: June 2018

Introduction

Le 31 janvier 2017, l’Ontario a retiré le fentanyl, l’hydromorphone et la
morphine à forte concentration des médicaments remboursables par les programmes
publics de médicaments s’ils sont prescrits par des médecins en soins non palliatifs. Nous
avons voulu évaluer les premiers effets de cette politique sur les schémas de prescription
et déterminer si ces effets variaient en fonction du type de prescripteur ainsi que du type
d’opioïdes et de leur concentration.

Méthodologie

Nous avons mené une étude transversale représentative de la population
auprès de patients nécessitant des soins palliatifs et des soins non palliatifs à qui du fentanyl,
de l’hydromorphone ou de la morphine couverts par les programmes publics de
médicaments de l’Ontario avaient été prescrits entre le 1er janvier 2014 et le 31 juillet 2017.
Pour chacun des mois de la période à l’étude, nous avons calculé le nombre total de
patients ayant reçu des opioïdes à forte concentration (réparti par type de prescripteurs)
ainsi que le volume total de chaque médicament délivré (réparti par concentration). Nous
avons utilisé des modèles autorégressifs à moyennes mobiles intégrés (ARMMI) interventionnels
pour évaluer les effets des changements apportés par la politique sur les habitudes
de prescription.

Résultats

Entre décembre 2016 et juillet 2017, le nombre total de patients ayant reçu des
opioïdes à forte concentration remboursés par le régime public a diminué de 98 % pour
l’ensemble des prescripteurs, passant de 5 930 à 133. La nouvelle politique a entraîné une
baisse substantielle du volume total des trois opioïdes délivrés, soit de 20 374 621 à
16 952 097 mg (p $lt; 0,01) pour l’hydromorphone, de 40 644 190 à 33 555 480 mg (p $lt; 0,03)
pour la morphine et de 9 604 913 à 5 842 405 mcg/h (p $lt; 0,01) pour le fentanyl. Dans le
cas du fentanyl et de l’hydromorphone, cette diminution a dans l’ensemble coïncidé avec
une augmentation du nombre d’opioïdes à faible concentration délivrés.

Conclusion

Le retrait des opioïdes à forte concentration a sensiblement réduit le nombre
de patients à qui ces médicaments ont été prescrits, ainsi que le volume total d’opioïdes à
action prolongée délivrés en Ontario dans le cadre du régime public de médicaments.
D’autres études devraient être menées pour en examiner les effets sur les patients.
Science and History of Science
Authors: Ferraz Márcia H. M. , Alfonso-Goldfarb Ana M. , Waisse Silvia
Published: June 2018

In the present article, we discuss the specificity of the object of the history of science as an autonomous and interdisciplinary field of studies by nature and origin, placed at the interface of history, epistemology and science, and focus on some key historiographical views. Within this context, Georges Canguilhem stands out for contributions such as calling the attention to the relevance of epistemology in science history research and the discontinuity-continuity antithesis, among many others. An accurate understanding of Canguilhem’s ideas demands an unbiased review of Auguste Comte’s work, particularly his views on science in general, the various sciences in particular and the methods to present them, to wit, the historical and the dogmatic. We finish with a short description of our theoretical-methodological work and its implications for studies in the history of science.
An Unknown Seal of the Convent of Cluj-Mănăștur
Authors: ȘTEFAN Andrei-Alexandru
Published: June 2018

The present paper wishes to examine the possibility regarding the existence of an unknown seal of the convent of Cluj-Mănăştur, one of the two major places of authentication in Late Medieval Transylvania. Starting from original documents dating back to the first decades of the 14th century, preserved by the national archives systems of Hungary and Romania, after detailed analyses one could observe the presence of several sealing traces of an ogival form, in contrast to the two round seals known by the subject’s historiography and used successively up to the mid-16th century. Therefore, the purpose of the present work is to bring several clarifications regarding these seal fragments, which in the end reveal themselves as one of the fundamental characteristic from the beginnings of this place of authentication.
Rezumat: Un sigiliu necunoscut al conventului de la Cluj-Mănăștur. Lucrarea de faţă îşi propune să examineze posibilitatea existenței unui sigiliu rămas până în prezent necunoscut al conventului benedictin de la Cluj-Mănăştur, unul dintre cele două locuri de adeverire majore ale Transilvaniei Evului Mediu Târziu. Pornind de la documente originale datând din primele decenii ale secolului al XIV-lea, păstrate în sistemele arhivelor naționale din Ungaria și România, în urma unor analize detaliate, s-au putut observa conservarea unor fragmente sigilare de formă ogivală, spre deosebire de cele două sigilii rotunde cunoscute istoriografiei subiectului ca fiind utilizate succesiv până la mijlocul secolului al XVI-lea. Prin urmare, scopul prezentului demers este de a aduce o serie de lămuriri cu referire la aceste resturi sigilare, care se dezvăluie drept una dintre caracteristicile fundamentale ale începuturilor acestui loc de adeverire.
Cuvinte-cheie: practică sigilară, sigiliu ogival, loca credibilia, diplomatică, abate.
Sermon Collections of Johannes Eck in Transylvanian Libraries
Authors: COTOI Paula
Published: June 2018

Several libraries from Transylvania hold in their historical collections works written by an important figure of the early modern Catholicism, Johannes Eck (1486-1543). The present paper looks at the volumes of this author, printed in the first half of the sixteenth century, paying special attention to sermon collections, prevalent among the books found in Transylvania. Their number is rather small, but the analysis of ownerships marks allows formulating some observations. Thus, the bibliographic component of the study, which identifies the preserved volumes, some of which have not been cataloged so far, is accompanied by a historical approach that questions the context of their reception. With a few exceptions, in which the the clues about ownership and the use of books are either missing or very late, Eck's works seem to have been circulated both during the dissemination of the ideas of the Reformation and after the adoption of the new denominations.
Rezumat: Colecții de predici ale lui Johannes Eck în bibliotecile din Transilvania. Câteva biblioteci din Transilvania păstrează în cuprinsul colecțiilor lor istorice lucrări ale unui important reprezentant al catolicismului epocii moderne timpurii, Johannes Eck (1486-1543). Lucrarea de față are în vedere volumele acestui autor, tipărite în prima jumătate a secolului al XVI-lea, acordând o atenție specială colecțiilor de predici, predominante în rândul cărților regăsite în Transilvania. Numărul acestora este destul de redus, dar analiza însemnărilor de proprietate permite formularea câtorva observații. Astfel, componenta bibliografică a studiului, prin care sunt identificate volumele păstrate, între care unele nu au fost catalogate până în prezent, este însoțită de o abordare istorică, ce chestionează contextul receptării lor. Cu câteva excepții, în care indiciile referitoare la proprietari și la utilizarea cărților fie lipsesc, fie sunt foarte târzii, lucrările lui Eck par a fi circulat atât în perioada răspândirii ideilor Reformei, cât și ulterior adoptării noilor confesiuni.
Cuvinte-cheie: colecții de predici, Reformă, Johannes Eck, Mediascher Predigtbuch, misiune franciscană.
Negative Theology in Contemporary Interpretations
Authors: Jugrin Daniel
Published: June 2018

The tradition of negative theology has very deep roots which go back to the Late Greek Antiquity and the Early Christian period. Although Dionysius is usually regarded as “the Father” of negative theology, yet he has not initiated a revolution in the religious philosophy, but rather brought together various elements of thinking regarding the knowledge of God and built a system which is a synthesis of Platonic, neo-Platonic and Christian ideas. The aim of this article is to illustrate the views of some more modern theologians on the nature, types and levels of apophaticism in the Greek Patristic tradition, trying to establish the role that negation can play in facilitating man’s attaining to the knowledge of God.
Divine Simplicity
Authors: Schärtl Thomas
Published: June 2018

This paper examines a variety of approaches in order to make sense of the doctrine of divine simplicity. Discussing the implications of traditional and contemporary philosophical concepts of divine simplicity, the author argues for taking the divine nature as a stupendous substance (in a Hegelian sense) to serve as the one and only truthmaker of statements regarding God, while we can resolve the predication problem which is caused by the idea that, as implied by divine simplicity, God is identical to his attributes if we conceive of the divine nature as an equivalent to Platonic forms.
Divine Simplicity and the Grammar of God-talk: Comments on Hughes, Tapp, and Schärtl
Authors: Muck SJ Otto
Published: June 2018

Different opinions about the simplicity of God may be connected with different understandings of how abstract terms are used to name the properties which are affirmed of a being. If these terms are taken to signify parts of that being, this being is not a simple one. Thomas Aquinas, who attributes essence, existence and perfections to God, nevertheless thinks that these are not different parts of God. When essence, existence and perfections are attributed to God, they all denominate the same, the Being of the first cause. For Aquinas, this is a consequence of his way of introducing the language about God by basing it upon the philosophical ways leading to God as first cause. Awareness of this connection between Divine attributes and the arguments for God’s existence is crucial for an adequate understanding of Aquinas’ position.
Panorama Quantitativo dos Programas de Pós-graduação Stricto Sensu em Tecnologia da Informação no Brasil
Authors: Falchi de Magalhães Fábio Luís , Del Raso Garcia Ruth , Coutinho Gonçalves de Souza Camila , Dos Santos Sartoratto Ruth , Costa Pastore Franco Elisangela Cristina , Gaspar Marcos Antonio
Published: June 2018

Com apenas 40 anos de existência, a Tecnologia da Informação (TI) tem sido objeto de estudo de diferentes áreas de pesquisa, tais como Administração, Computação, Ciências Sociais, Ciência da Informação e Comunicação. O objetivo desta pesquisa é apresentar um panorama quantitativo dos Programas de Pós-graduação Stricto Sensu na área de Tecnologia da Informação no Brasil. Para a realização desta pesquisa documental de abordagem quantitativa utilizou-se a Plataforma Sucupira da CAPES para a coleta de dados, tendo como recorte a coleta de dados em efetuada em dezembro de 2016. Os principais resultados auferidos indicam a existência de 249 cursos distribuídos em 178 Programas estabelecidos no país. Há 76 cursos de doutorado, 138 mestrados acadêmicos e 35 mestrados profissionais distribuídos em 97 Instituições de Ensino Superior. Assim, treze das 49 áreas de avaliação da CAPES têm cursos embasados com esta temática, com destaque para ‘Ciência da Computação’, além das áreas ‘Interdisciplinar’, ‘Comunicação e Informação’ e ‘Engenharias IV’, predominantemente com notas de avaliação ‘4’ e ‘3’. Há maior presença de Programas na Região Sudeste do Brasil, notadamente nos estados de São Paulo, Rio de Janeiro e Minas Gerais, sendo que as universidades federais se destacam perante outras instituições de ensino superior. Conclui-se que a TI como escopo de pesquisas está em plena expansão no país, sendo a sua abrangência interdisciplinar constatada nesta pesquisa.
Solvent Thermal Method to control Lead Sulfide Nano/Micron Crystal and Its Ni/PbS Composites
Authors: Ding Yajia , Bai Bing , Peng Jianan
Published: June 2018

Lead sulfide (PbS) is an important IV-VI semiconductor material with narrow bandwidth and wide wave width, which attracts people's attention. Nano-level PbS has many novel optoelectronic properties and has a wide range of applications in the field of optoelectronics, such as infrared optoelectronic devices, photovoltaic devices, light-emitting devices and display devices. In this paper, Pbs is produced by solvent thermal method by using lead acetate as lead source, sulfur power as sulfur source, ethylene glycol as solvent, and acetic acid to provide acidic environment. The reaction acidity, type of lead source, amount of sulfur source and other aspects will be explored. The products obtained under diﬀerent conditions were characterized by X-ray diﬀraction (XRD), optical microscopy and scanning electron microscopy (SEM). The results showed that PbS produced at 140°C for 24 hours, using 14mL ethylene glycol and 1.2mL acetic acid has the best morphology. It has a non-planar six-arm symmetrical structure. Finally, we prepare the lead sulfide composite Ni/PbS, and characterized it.
Research and Development of Ceramic Filtration Membrane
Authors: Deng Minglu , Chen Rong , Liu Sirong
Published: June 2018

Ceramic filter membrane plays an irreplaceable role in many fields because of its unique advantages. However, the complicated preparation process and high cost still limit the large scale application of ceramic filter membrane. Therefore, to improve the preparation process of ceramic filter membrane, optimize the membrane system structure is the ceramic filter membrane industry is facing major problems. In this paper, the structure, separation principle, preparation technology and application of ceramic filter membrane are introduced.
Analysis of Quality Factors of Online Video Streaming Based on Measurement
Authors: Xu Anyi
Published: June 2018

Spark is a low-latency, distributed computing system for large data sets. Spark is compatible with Hadoop data sources, but about 100 times faster than MapReducer, and is particularly well suited for machine learning. Spark is still in the embryonic stage, not yet high-speed development, with the Spark1.0.0 version of the release, marking the apache's top open source project Spark as a large data upstart, more and more attention by the IT industry will be widely used. Equipped with Spark platform and application of Spark to study the analysis of online video streaming media quality factors. This paper introduces the background knowledge of the research, and introduces and studies the composition and principle of Spark in detail. According to the needs of the experiment, the overall configuration of the platform is completed, its performance is verified, and its machine learning library is studied. First, we introduce the user requirements and architecture models of the widely accepted distributed file system in the industry. Then, the architecture of RDD is introduced. Finally, the relationship between the time of viewing video and the number of buffers is analyzed by KMeans machine learning algorithm, and the relationship of streaming media related factors is summarized. The platform used in the experiment is the Linux Ubuntu12.04LTS , the application is the Apache Spark platform. All the system preparation, debugging and testing are carried out in this experimental platform.
Implementation of QAM Modulation Demodulation Based on Simulink
Authors: Jiang Wanjian
Published: June 2018

This paper is about Simulink QAM modulation and demodulation implementation. Firstly, the basic principle of QAM modulation and demodulation system is introduced. Then, the basic operation of system modeling and simulation under simulation software Simulink is introduced. The emphasis is on modeling and simulation of 16QAM system modules, and 16QAM modulation and demodulation are realized. Finally, a 2DPSK system simulation is carried out to compare it with the 16QAM system. It is concluded that 16QAM is a relatively superior modulation and demodulation system.
An Analysis of China's Money Supply and Its Changes in 2008-2010
Authors: Wang Zhaoxin , Tang Tingting , Xia Xuebin , Yan Xiaohong
Published: June 2018

China divides the money supply into three levels: cash in circulation M0, cash that flows outside the banking system; the second is the narrow money supply M1, that is, M0 plus the deposit of enterprises and institutions; Money supply M2, that is, M1 plus enterprises and institutions of time deposits, household savings deposits and other deposits. In September 2008, China's monetary policy moderates easing in response to the serious impact of the international financial crisis. At the beginning of 2009, the State Council put forward an annual growth of about 17% M2, more than 5 trillion yuan of new loans, relative to the expected 8% GDP growth rate and 4% of the CPI index is still a moderately easy monetary policy. China's monetary policy this shift is correct, strong with the government's active fiscal policy, the role of economic stabilization and recovery is more obvious.
Anti - UV Finishing of Cotton Fabrics with Lithospermum Extract
Authors: Liu Shengbo , Zhao Lingxia , Wu Dongxu
Published: June 2018

Lithospermum extract from Lithospermum is a kind of naphthoquinone, which has good anti-ultraviolet and anti-bacterial function. In this paper, the eﬀects of diﬀerent treatment temperature, time and ratio of liquid to liquid on the UV resistance of Lithospermum erythrorhizon extract were studied. The optimum extraction conditions were as follows: extraction temperature 60 ℃, extraction time 2 h, ratio of liquid to liquid of Lithospermum and ethanol 1:11. In this paper, the anti-UV finishing of cotton fabric was carried out, and the anti-ultraviolet and whiteness of the fabric were taken as the main indexes. The optimum process of the anti-UV finishing was as follows: the impregnation temperature was 70 ℃, the immersion time was 2h, 1:40. Compared with the uncoated cotton fabric, the fabric UPF value of the fabric was improved from 12.31 to 83.25, and the anti-ultraviolet performance was excellent, and it had certain bacteriostatic eﬀect on Bacillus subtilis and Escherichia coli.
Assessment of the Possibilities of B-Mode Ultrasonography in the Diagnosis of Cervical Intervertebral Discs Hernia in Adolescents
Authors: Abdullaiev Rizvan Ya , Ibragimova Konul N , Tatyana A Ibragimova , Gorleku Philipp N , Abdullaiev Roman R
Published: June 2018

Objective: To improve the efficiency of cervical intervertebral discs hernia by determining the ultrasound biomarkers. Materials and Methods: The study included 38 healthy adolescents with normal intervertebral discs and neurologic status and 21 person with the disc hernia. Ultrasonography (USG) was performed at the level of disks C2-C3, C3-C4, C4-C5, C5-C6, C6-C7, C7-Тh1 in longitudinal and transverse projections. In axial section was performed the sagittal intervertebral disc and spinal canal sizes, the anterior dural space size, the width of spinal nerve canals. Results: In 9 (42,9±10,8% ) cases, the hernia was localized at the level of C5-C6, in 7 (33,3 ±10,3%) - C4-C5, in 2 (9,5±6,4%) - at the level of C2-C3 and C6-C7 C7, in 1 (4,8±4,7%) – at the level of C3-C4 respectively. In 13 (61,9±10,6%) cases the hernia had paramedian, in 5 (23,8±9,3%) cases – median, in 3 (14,3±7,6) cases – posterolateral localization. The paramedian hernia was significantly more frequently recorded than the posterolateral (P<0,05) and median hernia (p <0.001). Conclusions: In adolescents in the cervical spine, paramedian hernia are most commonly found, which are most often localized at the level of both C5-C6 and C4-C5. The greatest narrowing and deformation of the spinal nerve canal is observed by posterolateral and paramedian hernia, dural space – by median hernia respectively.
DICOM Standard and Its Application in PACS System
Authors: Yan Liting
Published: June 2018

PACS is an important link in the rapid development of information technology in contemporary hospitals. DICOM is the standard of PACS TCM medical image format and transmission medical image protocol. This paper describes the status of PACS system based on DICOM standard. In addition, the PACS system is described in detail according to its application classification and the characteristics and significance of DICOM standard are expounded. At the same time, it discusses the long-term prospect of DICOM in PACS.