bluuebunny/crossref_metadata_2025 huggingface dataset:
Persepsi Tubuh dan Bulimia Nervosa pada Remaja Putri
Authors: Shabah Zia Mu'tazzah , Dhanny Devieka Rhama
Published: March 2021

Latar belakang: Persepsi negatif pada remaja perempuan dapat menyebabkan meningkatnya kecenderungan terjadinya gangguan makan, salah satunya bulimia nervosa. Artikel ini bertujuan untuk melihat apakah terdapat hubungan antara persepsi tubuh terhadap kejadian bulimia nervosa sebagai salah satu bentuk gangguan makan. Artikel yang diambil merupakan studi literatur tahun 2010 hingga 2020. Data diambil dari database google scholar dengan kata kunci bulimia nervosa, persepsi tubuh, gangguan makan, perempuan. Hasil: berdasarkan studi literatur didapatkan 4 dari 10 artikel yang sesuai dengan kriteria inklusi yaitu artikel dengan full pdf, sampel perempuan, memiliki judul dan isi yang sesuai dengan tujuan  dan dipublikasikan pada tahun 2010-2020. Sedangkan, kriteria eksklusi yaitu artikel yang strukturnya tidak lengkap, membahas selain gangguan makan bulimia nervosa dan persepsi tubuh. Dari artikel yang memenuhi kriteria inklusi, dapat diketahui bahwa terdapat hubungan antara persepsi tubuh dengan kejadian bulimia nervosa. Kesimpulan: Aspek perilaku yang mempengaruhi kejadian gangguan makan bulimia nervosa yaitu penampilan fisik, orientasi pada penampilan, kepuasan terhadap bagian tubuh, keinginan mewujudkan tubuh ideal, pengkategorian ukuran tubuh,  kecemasan menjadi gemuk,perilaku gangguan makan.
Nothing Normal About the New World: A Vision for Post-COVID International Development
Authors: Sindall Rebecca , Mallory Adrian
Published: March 2021

COVID-19 has exposed many fault lines in international development. As international staff were repatriated, the need to support communities with basics such as sanitation and hygiene once again fell to local organisations, who are often underfunded, in part because of the international development funding structures that are stacked against them. We argue that these structures lead to tokenistic partnerships, intervention design driven by short-term trends rather than the needs of communities, and ecological damage to the detriment of the very communities we claim to support. We argue that international development must take this opportunity to become more cognisant of and accountable for our carbon footprint, to develop new ways to support those organisations most closely linked to the communities they serve, to engage with the wider politics that has brought us to this point, and to commit to a future that redresses the inequalities of the past.
A fumaça digital: inversão infraestrutural do COVID-19 pela perspectiva Yanomami
Authors: Pelanda Mateus F. L. , Van Amstel Frederick M. C.
Published: March 2021

A pandemia do coronavírus COVID-19 revelou fragilidades nos sistemas sócio-técnicos modernos. No Sul global, ela tornou visível o projeto político/empresarial que se beneficia de opressões enquanto se esquiva de discursos internacionais de preservação das pessoas e da natureza. Através do entrelaçamento dos conceitos de inversão infraestrutural, dos estudos de infraestrutura, com os conceitos de Omama, Urihi-a, Hutukara e Xawara do xamanismo yanomami, este ensaio busca compreender as conexões político-ecológicas que se tornaram aparentes durante o fenômeno da pandemia no Brasil. O trabalho reconstrói a narrativa da pandemia a partir do mapeamento das relações históricas de opressões que emergiram durante este processo. O texto se encerra com reflexões e apontamentos metodológicos sobre possibilidades de mudança de foco nas práticas de projetos de infraestruturas de informação a partir do pensamento ameríndio.
Features Selection for Entity Resolution in Prostitution on Twitter
Authors: Permatasari Reisa , Rakhmawati Nur Aini
Published: March 2021

Entity resolution is the process of determining whether two references to real-world objects refer to the same or different purposes. This study applies entity resolution on Twitter prostitution dataset based on features with the Regularized Logistic Regression training and determination of Active Learning on Dedupe and based on graphs using Neo4j and Node2Vec. This study found that maximum similarity is 1 when the number of features (personal, location and bio specifications) is complete. The minimum similarity is 0.025662627 when the amount of harmful training data. The most influencing similarity feature is the cellphone number with the lowest starting range from 0.997678459 to 0.999993523.  The parameter - length of walk per source has the effect of achieving the best similarity accuracy reaching 71.4% (prediction 14 and yield 10).
HUBUNGAN ANTARA JENIS / BENTUK, UKURAN, DAN BAHAN FASILITAS DUDUK TERHADAP DURASI DUDUK PENGUNJUNG: STUDI KASUS CAFE EDUPLEX
Authors: Maulida Aulia Fiya , Wulandari Ratri
Published: March 2021

Fasilitas duduk merupakan elemen penting yang berperan dalam menentukan tingkat kenyamanan di sebuah cafe atau restoran. Penelitian ini dilakukan untuk menganalisa lamanya pengunjung bertahan di dalam cafe sesuai fasilitas duduk yang digunakan dan mengambil kasus Cafe Eduplex di jalan Ir. H. Djuanda, Dago. Dalam penelitian ini membahas tentang hubungan antara jenis, ukuran dan bahan sebuah fasilitas duduk, terhadap frekuensi lamanya pengunjung yang datang di cafe tersebut.

Metode penelitian yang digunakan adalah deskripsi kualitatif. Pertama, mengumpulkan data-data berupa teori tentang macam-macam jenis, ukuran standart dan bahan sebuah fasilitas duduk serta efeknya terhadap kenyamanan dan psikologi pengunjung, yang menyebabkan adanya perbedaan durasi waktu berkunjung. Kedua, pengumpulan data lapangan dengan memperhatikan jenis, ukuran dan bahan fasilitas duduk yang ada pada cafe tersebut, serta memperhatikan jenis pengunjung dan perbedaan lamanya waktu pengunjung berada di cafe tersebut. Selanjutnya, membandingkan data-data yang sesuai dan berkesinambungan antara teori tertulis pada literatur, yang berisi tentang jenis atau bentuk, ukuran dan bahan fasilitas duduk serta efek yang ditimbulkannya dengan data lapangan yang terkumpul berupa jenis atau bentuk, ukuran dan bahan fasilitas duduk yang ada di cafe tersebut, serta lama pengunjung berada disana.

Hasil penelitian menunjukkan bahwa perbandingan antara hasil pengumpulan data lapangan dan literatur yang terkumpul sesuai. Jenis fasilitas duduk beserta ukuran dan bahannya berpengaruh dengan durasi pengunjung yang datang. Karena adanya perbedaan rasa nyaman yang ditimbulkan oleh fasilitas duduk tersebut.

Kata Kunci: Fasilitas duduk, Kenyamanan, Waktu berkunjung, Cafe
KAJIAN KEBUTUHAN MEJA BELAJAR BAGI SISWA SEKOLAH DASAR DI FASILITAS PENGUNGSIAN BENCANA
Authors: Sakya Kharista Astrini , Satriaji Kukuh Rizki , Danurdoro Dwi Hatmojo , Alfin Eljihadi
Published: March 2021

Pendidikan adalah salah satu faktor terpenting yang akan membangun karakter bangsa di masa depan. Pemerintah juga menjelaskan bahwa setiap warga negara memiliki hak yang sama untuk memperoleh pendidikan yang berkualitas, meskipun berada di daerah terpencil, terbelakang atau berkebutuhan khusus (UU No. 20 tahun 2003 pasal 5). Salah satu daerah yang dianggap memiliki kebutuhan khusus adalah daerah pascabencana. Dalam beberapa tahun terakhir, berbagai daerah di Indonesia telah terkena bencana alam, seperti gempa bumi, banjir, tsunami, dll. Contohnya adalah Pulau Lombok, yang mengalami gempa besar 2018 di Indonesia. Pemerintah, melalui Kementerian Pendidikan dan Kebudayaan, serta beberapa LSM, telah melakukan beberapa upaya dengan mendirikan tenda sekolah darurat di beberapa pengungsian, tetapi biasanya tidak dilengkapi dengan fasilitas yang baik. Beberapa sekolah darurat hanya terdiri dari tenda terbuka, dengan siswa belajar dan menulis di lantai. Penelitian ini bertujuan membuat kriteria desain meja belajar untuk siswa sesuai dengan kondisi tersebut. Metode yang digunakan dalam penelitian ini adalah observasi lapangan dengan pertanyaan yang diberikan kepada siswa dan guru di sekolah darurat, kemudian analisis konten dilakukan untuk menentukan kriteria desain yang sesuai. Hasil penelitian ini diharapkan dapat diimplementasikan ke dalam desain meja yang praktis, ringan, dan mudah dioperasikan dengan mempertimbangkan penggunaannya oleh siswa sekolah dasar dengan kondisi darurat.
STUDI WINDOW-TO-WALL RATIO PADA KANTOR PEMERINTAH DI JAKARTA SELATAN
Authors: Dwiana Melisa Imam , Purnomo Agus Budi , Rahmah Nuzuliar
Published: March 2021

Kantor pemerintah merupakan bangunan yang diharapkan dapat menjadi contoh sebagai bangunan hemat energi yang baik. Banyak usaha yang dapat dilakukan untuk menghemat energi, salah satunya memperhatikan desain fasade. Jendela sebagai bukaan pada fasade dapat diatur sedemikian rupa sehingga panas matahari tidak membuat peningkatan energi untuk mendinginkan ruangan sekaligus mengurangi penggunaan lampu pada siang hari. Salah satu aspek yang dapat digunakan untuk menilai kinerja bukaan jendela adalah Window-to-Wall Ratio (WWR). Rasio diperoleh dengan membagi total luas bukaan pada dinding yang menggunakan kaca dengan luas permukaan keseluruhan bidang selubung bangunan. Tujuan dari penelitian ini adalah mempelajari nilai WWR dari bangunan kantor pemerintahan yang ada di Jakarta Selatan. Penelitian ini menggunakan tampak bangunan dari 20 gedung kantor pemerintahan di Jakarta Selatan sebagai kasus studi. Hasil penelitian berupa nilai rata rata WWR kantor pemerintahan yang nantinya dibandingkan dengan rata-rata WWR kantor sejenis dari literatur lain. Dari hasil penelitian, diperoleh rata rata nilai WWR sama dengan 24.6%, yang mana masih berada di rentang WWR dalam penelitian lain.Kata kunci : Hemat Energi, Selubung Bangunan, Kantor Pemerintah, Window-to-Wall Ratio (WWR)
Authors: Sidabutar Yuanita FD
Published: March 2021

The potential for cultural tourism in Medan City in historical buildings. Objective 1) for to determine the quality of buildings on community participation in historical buildings in Medan City. 2) knowing the condition of the building's environmental area towards community participation in historical buildings in Medan City. 3) knowing the quality of the building and the condition of the environmental area on community participation in historical buildings in Medan City. The sample was 218 people. The data collection technique was distributed by questionnaires. Data was processed using Statistical Product Service and Solution version 20.0 for windows. Multiple linear regression data analysis techniques with the formula Y = a + b1X1 + b2X2. The result of multiple linear regression test is R2 of 0.637 or 36.3%, that there is an effect of building quality and environmental conditions on community participation in historical buildings in Medan City. With the results of the F test (Simultaneous) obtained Fcount of 35.53 and Ftable of 1.04, thus Fcount 35.53> Ftable 1.04 and it can be concluded that the quality of buildings and environmental conditions on community participation in historic buildings in Medan City have a significant effect.Keywords: Building Quality, Environmental Conditions, and Community Participation
Multiple Artery Aneurysms: Unusual Presentation of IgG4 Vasculopathy
Authors: Yadav Anurag , Godasu Geetha , Buxi Tarvinder Bir Singh , Sheth Swapnil
Published: March 2021

Immunoglobulin G4 (IgG4)-related disease is a chronic systemic disease. It is characterized by inflammatory fibrosis and high serum IgG4 levels. IgG4-positive plasma cells infiltrate target organs in this disease. It may involve the pancreas, biliary tract, lacrimal glands, salivary glands, orbits, thyroid, kidneys, lymph nodes, or retroperitoneum. It may present as vasculitis with involvement of large to medium sized vessels such as the aorta, the common iliac, carotid, and coronary arteries. We present a case of 55-year-old male patient who presented with shortness of breath on exertion and atypical chest pain. On CT angiography, a giant coronary artery aneurysm involving the left anterior descending artery, multiple visceral and intercostal artery aneurysms, and nodular paravertebral soft-tissue thickening secondary to IgG4 vasculopathy.
Surface Chemistry of Perovskite Oxynitride Photocatalysts: A Computational Perspective
Authors: Bouri Maria , Ninova Silviya , Ouhbi Hassan , Vonrüti Nathalie , Aschauer Ulrich
Published: March 2021

Perovskite oxynitrides are an established class of photocatalyst materials for water splitting. Previous computational studies have primarily focused on their bulk properties and have drawn relevant conclusions on their light absorption and charge transport properties. The actual catalytic
conversions, however, occur on their surfaces and a detailed knowledge of the atomic-scale structure and processes on oxynitride surfaces is indispensable to further improve these materials. In this contribution, we summarize recent progress made in the understanding of perovskite oxynitride
surfaces, highlight key processes that set these materials apart from their pure oxide counterparts and discuss challenges and possible future directions for research on oxynitrides.
Conference Report of the 3rd Swiss Symposium in Point-of-Care Diagnostics held online on 29 October 2020
Authors: Pfeifer Marc E. , Ulrich Dieter
Published: March 2021

The COVID-19 pandemic has raised in 2020 an unprecedented need for diagnostic testing, especially rapid testing, for SARS-CoV-2 infections. POC diagnostic tools, however, have clearly also importance in other domains such as oncology and women's health, because of the efficiency and
convenience factors playing an increasingly important role in a mobile (and sometimes confined) and digitally connected world. Out of necessity, the 3rd edition of the Swiss Symposium in POC Diagnostics, originally planned to take place at the La Poste Conference Center in Visp,
was smoothly run online with 170 engaged participants from science, industry and laboratory medicine.
Decentralized Relay Selection in Multi-User Multihop Decode-and-Forward Relay Networks
Authors: Senanayake R , Atapattu S , Evans JS , Smith Peter
Published: March 2021

This paper analyzes the performance of a multi-user multihop relay network using a low complexity decentralized relay selection (DRS) scheme for decode-and-forward cooperative networks. We carry out a rigorous diversity order analysis, with Nakagami- m fading and pathloss and show that the DRS scheme achieves full diversity while maintaining a complexity that is quadratic in the number of users, quadratic in the number of relays and independent of the number of hops. For a special case of two-user networks we derive exact closed-form expressions for the outage probability by considering the order statistics. Furthermore, we extend our analysis to consider interfering relay networks and derive an accurate lower bound on the outage of an arbitrary network user. Based on the lower bound we also show how the outage probability saturates in the high signal-to-interference-plus-noise ratio regime. Extensive numerical examples are used to illustrate the accuracy of the analysis and to highlight the use of the DRS scheme in multi-user multihop relay networks.

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Predicting Drug-Induced Liver Injury Using Convolutional Neural Network and Molecular Fingerprint-Embedded Features
Authors: Nguyen-Vo TH , Nguyen L , Do N , Le PH , Nguyen TN , Nguyen Binh , Le L
Published: March 2021

© 2020 American Chemical Society. As a critical issue in drug development and postmarketing safety surveillance, drug-induced liver injury (DILI) leads to failures in clinical trials as well as retractions of on-market approved drugs. Therefore, it is important to identify DILI compounds in the early-stages through in silico and in vivo studies. It is difficult using conventional safety testing methods, since the predictive power of most of the existing frameworks is insufficiently effective to address this pharmacological issue. In our study, we employ a natural language processing (NLP) inspired computational framework using convolutional neural networks and molecular fingerprint-embedded features. Our development set and independent test set have 1597 and 322 compounds, respectively. These samples were collected from previous studies and matched with established chemical databases for structural validity. Our study comes up with an average accuracy of 0.89, Matthews's correlation coefficient (MCC) of 0.80, and an AUC of 0.96. Our results show a significant improvement in the AUC values compared to the recent best model with a boost of 6.67%, from 0.90 to 0.96. Also, based on our findings, molecular fingerprint-embedded featurizer is an effective molecular representation for future biological and biochemical studies besides the application of classic molecular fingerprints.
IPseU-NCP: Identifying RNA pseudouridine sites using random forest and NCP-encoded features
Authors: Nguyen-Vo TH , Nguyen QH , Do TTT , Nguyen TN , Rahardja S , Nguyen Binh
Published: March 2021

© 2019 Nguyen-Vo et al. Background: Pseudouridine modification is most commonly found among various kinds of RNA modification occurred in both prokaryotes and eukaryotes. This biochemical event has been proved to occur in multiple types of RNAs, including rRNA, mRNA, tRNA, and nuclear/nucleolar RNA. Hence, gaining a holistic understanding of pseudouridine modification can contribute to the development of drug discovery and gene therapies. Although some laboratory techniques have come up with moderately good outcomes in pseudouridine identification, they are costly and required skilled work experience. We propose iPseU-NCP - an efficient computational framework to predict pseudouridine sites using the Random Forest (RF) algorithm combined with nucleotide chemical properties (NCP) generated from RNA sequences. The benchmark dataset collected from Chen et al. (2016) was used to develop iPseU-NCP and fairly compare its performances with other methods. Results: Under the same experimental settings, comparing with three state-of-the-art methods including iPseU-CNN, PseUI, and iRNA-PseU, the Matthew's correlation coefficient (MCC) of our model increased by about 20.0%, 55.0%, and 109.0% when tested on the H. sapiens (H_200) dataset and by about 6.5%, 35.0%, and 150.0% when tested on the S. cerevisiae (S_200) dataset, respectively. This significant growth in MCC is very important since it ensures the stability and performance of our model. With those two independent test datasets, our model also presented higher accuracy with a success rate boosted by 7.0%, 13.0%, and 20.0% and 2.0%, 9.5%, and 25.0% when compared to iPseU-CNN, PseUI, and iRNA-PseU, respectively. For majority of other evaluation metrics, iPseU-NCP demonstrated superior performance as well. Conclusions: iPseU-NCP combining the RF and NPC-encoded features showed better performances than other existing state-of-the-art methods in the identification of pseudouridine sites. This also shows an optimistic view in addressing biological issues related to human diseases.
IProDNA-CapsNet: Identifying protein-DNA binding residues using capsule neural networks
Authors: Nguyen Binh , Nguyen QH , Doan-Ngoc GN , Nguyen-Vo TH , Rahardja S
Published: March 2021

© 2019 The Author(s). Background: Since protein-DNA interactions are highly essential to diverse biological events, accurately positioning the location of the DNA-binding residues is necessary. This biological issue, however, is currently a challenging task in the age of post-genomic where data on protein sequences have expanded very fast. In this study, we propose iProDNA-CapsNet - a new prediction model identifying protein-DNA binding residues using an ensemble of capsule neural networks (CapsNets) on position specific scoring matrix (PSMM) profiles. The use of CapsNets promises an innovative approach to determine the location of DNA-binding residues. In this study, the benchmark datasets introduced by Hu et al. (2017), i.e., PDNA-543 and PDNA-TEST, were used to train and evaluate the model, respectively. To fairly assess the model performance, comparative analysis between iProDNA-CapsNet and existing state-of-the-art methods was done. Results: Under the decision threshold corresponding to false positive rate (FPR) ≈ 5%, the accuracy, sensitivity, precision, and Matthews's correlation coefficient (MCC) of our model is increased by about 2.0%, 2.0%, 14.0%, and 5.0% with respect to TargetDNA (Hu et al., 2017) and 1.0%, 75.0%, 45.0%, and 77.0% with respect to BindN+ (Wang et al., 2010), respectively. With regards to other methods not reporting their threshold settings, iProDNA-CapsNet also shows a significant improvement in performance based on most of the evaluation metrics. Even with different patterns of change among the models, iProDNA-CapsNets remains to be the best model having top performance in most of the metrics, especially MCC which is boosted from about 8.0% to 220.0%. Conclusions: According to all evaluation metrics under various decision thresholds, iProDNA-CapsNet shows better performance compared to the two current best models (BindN and TargetDNA). Our proposed approach also shows that CapsNet can potentially be used and adopted in other biological applications.
Classification of adaptor proteins using recurrent neural networks and PSSM profiles
Authors: Le NQ Khanh , Nguyen QH , Chen X , Rahardja S , Nguyen Binh
Published: March 2021

© 2019 The Author(s). Background: Adaptor proteins are carrier proteins that play a crucial role in signal transduction. They commonly consist of several modular domains, each having its own binding activity and operating by forming complexes with other intracellular-signaling molecules. Many studies determined that the adaptor proteins had been implicated in a variety of human diseases. Therefore, creating a precise model to predict the function of adaptor proteins is one of the vital tasks in bioinformatics and computational biology. Few computational biology studies have been conducted to predict the protein functions, and in most of those studies, position specific scoring matrix (PSSM) profiles had been used as the features to be fed into the neural networks. However, the neural networks could not reach the optimal result because the sequential information in PSSMs has been lost. This study proposes an innovative approach by incorporating recurrent neural networks (RNNs) and PSSM profiles to resolve this problem. Results: Compared to other state-of-the-art methods which had been applied successfully in other problems, our method achieves enhancement in all of the common measurement metrics. The area under the receiver operating characteristic curve (AUC) metric in prediction of adaptor proteins in the cross-validation and independent datasets are 0.893 and 0.853, respectively. Conclusions: This study opens a research path that can promote the use of RNNs and PSSM profiles in bioinformatics and computational biology. Our approach is reproducible by scientists that aim to improve the performance results of different protein function prediction problems. Our source code and datasets are available at https://github.com/ngphubinh/adaptors.
Hypothesis of "Open Ends". (On the Issue of the Structure of the Cardiovascular System at the Border of the Arterial and Venous Branches)
Authors:   Institute of Geology and Oil and Gas Technologies, Kazan (Volga Region) Federal University, Kazan, Russian Federation, Komarov B. N.
Published: March 2021

The hypothesis of British physiologist Starling explaining the mechanism of venous rise is considered. The theoretical arguments demonstrating its insolvency are presented. The principal one is, that Sterling’s hypothesis contradicts basic laws of physics. It is offered, for discussion, the hypothesis explaining venous rise not contradicting with physical laws. The hypothesis is based on the idea, that the common view of physiologists and doctors on the locked anatomy of blood circulation system is false. Examples of “open end” circulation in muscle and lung based on capillary effect and not on diffusion are presented.
Pharmacophoric Analysis of the Structure of a New 1,3,4-Thiadiazolylamide Derivative of Valproic Acid
Authors:   Tver State Medical University, Tver, Russian Federation, Malygin A. S. , Yasnetsov V. V. ,   State Scientific Center of the Russian Federation – Institute of Medical and Biological Problems of the Russian Academy of Sciences, Moscow, Russian Federation
Published: March 2021

Pharmacophoric analysis of the structure of valprazolamide, a 1,3,4-thiadiazolylamide derivative of valproic acid, was carried out. It was shown that the new valproate contains a substituted amide group, hydrophobic and electron-donor domеns – pharmacophores, determining its antiepileptic activity. Valproic acid has only a hydrophobic moiety. Modification of valproic acid by introducing an additional pharmacophore, 1,3,4-thiadiazole, into its structure leads to a decrease in toxicity and an increase in antiepileptic activity.
Analysis and Prediction Outcomes of Retinopathy of Prematurity in Children Born in Different Solar Activity
Authors:   S. Fyodorov Eye Microsurgery Federal State Institution, Tambov branch, Tambov, Russian Federation, Kutimova E. Y. , Matrosova Yu. V. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Tambov branch, Tambov, Russian Federation, Shutova S. V. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Tambov branch, Tambov, Russian Federation
Published: March 2021

Purpose: Analysis and prognostic outcomes of retinopathy of prematurity (ROP) depending on the solar activity at birth time and gestational age. Material and methods. 229 case histories of premature babies born within 2017-2019 were randomly selected. They were split into two groups: group I – children with ROP (1, 2 and 3 degree) and group II – without any ROP (pre retinopathy). The disease outcome was taken into account in the children with ROP: laser coagulation (LC) and spontaneous regression. Also, all children were split according to the seasons of birth: winter, spring, summer and autumn. Results. The seasonal differences in retinopathy outcomes were observed: in children born in spring and summer, the percentage of spontaneous regression was much lower and was 15% in spring, 13.2% in summer, 29% in autumn and 29.6% in winter. The percentage of performed LC on the contrary was 21.7%-28.3% in spring and summer period and 9.7%-14.8% in autumn and winter. Conclusion. A mathematical model is constructed for predicting the outcome of retinopathy of prematurity, determining the probability of spontaneous regression of the disease based on such independent variables as the level of insolation and the gestational age of the child. According to the obtained formula, the probability of spontaneous regression of retinopathy increases with an increase in gestational age and a decrease in solar activity at birth time. On the contrary, the probability of need for laser coagulation increases with a decrease in gestational age and an increase in the insolation intensity.
Biological Activity of New 1-Benzoyl-Subctituted 6-(Methylthio)-4-Chloro-1h-Pyrazolo[3,4-D]Pyrimidines
Authors:   St. Petersburg State University of Chemistry and Pharmacy, Ministry of Health of the Russian Federation, St. Petersburg, Russian Federation, Ofitserova E. S. , Alekseeva L. N. ,   St. Petersburg State University of Chemistry and Pharmacy, Ministry of Health of the Russian Federation, St. Petersburg, Russian Federation, Shklyarenko A. A. ,   St. Petersburg State University of Chemistry and Pharmacy, Ministry of Health of the Russian Federation, St. Petersburg, Russian Federation, Yakovlev I. P. ,   St. Petersburg State University of Chemistry and Pharmacy, Ministry of Health of the Russian Federation, St. Petersburg, Russian Federation
Published: March 2021

The article presents results of the study of the biological activity of newly synthesized 1-benzoyl-substituted-6- (methylthio) -4-chloro-1H-pyrazolo [3,4-d] pyrimidines. The acute toxicity of 2-aryl-6- (methylthio) -4-chloro-2H-pyrazolo [3,4-d] pyrimidines was determined experimentally on non-linear white male mice with a total weight of 16-20 g. A generation model was used to experimentally evaluate the analgesic activity acetic "writhing" in mice. It was experimentally confirmed that the synthesized new 2-aryl-6- (methylthio) -4-chloro-2H-pyrazolo [3,4-d] pyrimidines are non-toxic and have pronounced analgesic activity.
Information Feedback Between Size Portfolios in Boursa Kuwait
Authors: Alhajraf Saad
Published: March 2021

This paper examines the transmission of information between small and large sized portfolios within the Boursa Kuwait between 2011 and 2020.  The study documents a constant and steady stream of feedback which demonstrates a sizeable and significant impact on market volatility; albeit at varying degrees of effect on smaller portfolios as compared with larger ones.  Evidence suggests a more persistent volatility on larger portfolios, indicating a disparity on the interpretations of transmitted information between the varied styles of investors in the Kuwait Boursa.
Characterization of the Sulfide Deposits in the Southeastern Nigeria Using VLF Method: Insights from Numerical Modeling and Field Examples
Authors: Falebita D. E. , Afolabi O. , Soyinka B. O , Adepelumi A. A.
Published: March 2021

A priori geologic and geophysical information has been used to construc conceptual VLF experiments on conductively and inductively coupled overburden geological models of the lead-zinc (Pb-Zn) mineralization zone found in southeastern Nigeria.This is based on the finite element approach to (1) simulate different geologic situations of overburden occurrence, (2) examine the roles played by overburden in modifying and masking VLF responses of a buried conductor target, and (3) confirm the effectiveness of VLF method in mapping lead-zinc lodes found in sedimentary terrains.The computed theoretical model curves and field examples are expected to serve as guide for VLF anomaly pattern recognition due to overburden thickness, resistivity and width of conductor in similar terrain as the study area.
IMPLEMENTASI PEMBELAJARAN TEMATIK KURIKULUM 2013 DALAM PEMBENTUKAN KARAKTER SISWA
Authors: Sofiyatunningtiyas Tetes Nur , Nugroho Agung , Muslim Arifin
Published: March 2021

Abstract. The ongoing curriculum 2013 is inseparable from strengthening the character. Strengthening character can be integrated through thematic learning carried out in class. The study aimed to describe the implementation of thematic learning based on 2013 curriculum in the context of building the characters of responsibility and teamwork on theme 9 for grade IV SD Negeri 1 Patikraja. This research implemented a qualitative approach with descriptive type. Data were obtained by observing, interviewing, and documenting. Data obtained were then analyzed through Miles and Huberman analysis model to draw conclusions. The results indicated that the implementation of character education consisted of integrating learning achievements in the form of planning, implementation and evaluation, educational institution synergize in strengthening character education, teacher competency strength and role models in implementing character education of responsibilities and teamwork. Supporting factors of the implementation in thematic learning were active students and teacher skills to build the character of children. The obstacles faced by teachers were limited facilities and infrastructure, time, student awareness and family factors. The solutions to overcome the obstacles were the teacher summarized the learning material, the teacher used the available facilities and infrastructure, the teacher approached the students with assistance and supervision, the teacher established good communication with studentsï¿½ parents.
TAHAP PENGEMBANGAN BAHAN AJAR “CREATIVE FACTOR” BERBASIS PROYEK PADA MATERI KELIPATAN DAN FAKTOR BILANGAN DIKELAS IV SEKOLAH DASAR
Authors: Riana Ina , Kusumadewi Rida Fironika , Ulia Nuhyal
Published: March 2021

Abstrak. This research is to develop and find out the feasibility of "Creative Factor" teaching material products on multiples and number factors. "Creative Factor" teaching material products multiples and number factors are developed based on the teacher's need for other reference sources in learning. This research uses the Research and Development (RnD) method. The development of "Creative Factor" teaching material products uses a development research procedure according to Sugiyono that contains 10 thrones. Based on this, the research results obtained include: (1) the validation results from 4 experts obtained an average score of 84 and a percentage of 90% with the criteria "Very Eligible". (2) the results of the small-scale test get teacher responses obtained by the percentage of 88% with the criteria "Very Practical". While the results of student responses obtained 97.2% percentage "Very Practical". (3) large-scale test results obtained by teacher responses obtained by the percentage of 90% with the criteria "Very Practical". While the results of student responses obtained 96% percentage "Very Practical". Based on these results, the development of "Creative Factor" teaching material products can be declared worthy to be used as a companion in the learning process.
Vladimir Alekseevich Karlov (on the occasion of his 95th birthday)
Authors: Editorial Article
Published: March 2021

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ESKİ ANADOLU TÜRKÇESİ BAĞLAMINDA "OHT" SÖZCÜĞÜ
Authors: BÜKE Himmet
Published: March 2021

Eski Anadolu Türkçesi, XI. yüzyılda Oğuz Türklerinin Anadolu coğrafyasına göçleriyle başlayan süreçte oluşan ve ‎daha sonraki yüzyıllarda Batı Türkçesinin temelini teşkil edecek olan yazı dilinin adıdır. Bu dönem Osmanlı Türkçesi ‎dönemiyle devam ederek bugün resmî konuşma ve yazı dilimiz olan Türkiye Türkçesinin de temelini oluşturur. ‎Selçukluların Anadolu coğrafyasına girişiyle yoğun bir Türk nüfusu fethedilen bölgelere yerleşmiş bununla beraber ‎Türkçenin bu yeni coğrafyada konuşma ve yazı dili olma süreci başlamıştır. Türkçenin Anadolu’daki bu ilk yıllarına ait ‎bugüne ulaşabilmiş yazılı eser sayısı oldukça sınırlıdır. Bunda Selçuklu Devleti’nin Türkçeyi devlet ve bürokrasi dili ‎olarak kullanmaması, Arapça ve Farsçanın ulema ve devlet adamları tarafından tercih edilmesi etkilidir. Eski Anadolu ‎Türkçesi verimli ve en güçlü dönemini Selçuklu Devleti sonrası Anadolu coğrafyasının farklı bölgelerinde kurulmuş ‎olan beylikler zamanında yaşamıştır. Beylikler döneminde Anadolu’nun farklı şehirleri beylik merkezleri olmuş ve bu ‎merkezlerde Türkçenin Anadolu sahasındaki önemli ve çok kıymetli eserleri verilmiştir. Anadolu’da Türkçenin yazı dili ‎olma süreci bu dönemde önemli ölçüde mesafe kat etmiştir. Bugün bu dönemden kalan eserlerin hemen hemen hepsi ‎incelenmiş haklarında pek çok ilmî çalışma yapılmıştır. Dönemin sözvarlığı çeşitli sözlüklerde ve incelenen eserlerin ‎dizin bölümlerinde ortaya konulmuş yine dönemin gramer özellikleri büyük ölçüde tespit edilmiştir. Fakat dönemin ‎sözvarlığı içerisinde üzerinde tekrar durulması, müstakil çalışmalar yapılması gereken pek çok sözcük bulunmakta bu ‎sözcüklerin Eski Türkçe, Orta Türkçe ve günümüz lehçelerindeki görünümlerine bakılması gerekmektedir. Sadece bir ‎eserde tespit edilen hapaksları da bu tür derinlemesine çalışmalarla yeniden anlamlandırma imkanı ortaya çıkacaktır. Bu ‎çalışmada sadece Eski Anadolu Türkçesi dönemi eserlerinde kullanılmış olan “oht” sözcüğü ele alınacaktır. Bu sözcük ‎Türkçenin başka dönemlerinde yazılan eserlerde tespit edilmemiş olup sadece Eski Anadolu Türkçesine mahsus bir ‎kullanımdır. Sözcük hakkındaki genel görüş; Arapça “vakt” sözcüğüyle ilgili olduğudur. Bu sözcüğün Türkçeye ‎girdikten sonra fonetik değişikliğe uğradığı ve bir söyleyiş biçimi kazandığı düşünülse de konuyla ilgili farklı tespitleri ‎verecek bu sözcüğü tartışmaya açacağız. Sözcüğün Türkçe kökenli mi yoksa yabancı menşeili mi olduğu üzerinden ‎giderek tarihsel sürece ve sözcüğün kullanım alanlarına bir yorum getirmeye çalışacağız. Yazılı kaynakların tanıklığının ‎yanı sıra sözcüğün Anadolu ağızlarındaki kullanımı da değineceğiz. Bu konuda Anadolu ağızlarının ciddi bir belirleyici ‎olduğunu düşünmekle beraber Türkçenin farklı lehçelerindeki tarihi metinler ele alınıp bu sözcüğün veya bu sözcükle ‎bağlantılı olduğu düşünülen sözcüklerin köken ve bağlamları ortaya konulacaktır.‎
Carcinogenic and Non-carcinogenic Health Risk Assessment of Heavy Metals in Njaba River, Imo State, Nigeria
Authors: Eze Victor , Ndife Chidiebere , Muogbo Miracle
Published: March 2021

Daily exposure to potentially toxic elements (heavy metals) through the oral ingestion of water has been a major concern to human health due to its detrimental effects. Studies focusing on health risk assessment of potentially toxic elements in surface and ground waters have been conducted, but none has been reported in Njaba River. Few studies conducted have focused only on the assessment of its water quality. Therefore, this study assessed the carcinogenic and non-carcinogenic effects of the potentially toxic elements (As, Cd, Cr, Cu, Ni, Pb, and Zn) in Njaba River. Overall, a total of 135 water samples was collected for this study and were analyzed using Agilent FS240AA AAS. The potentially toxic elements concentrations were: As (0.015±0.001 to 0.021±0.001 mg L-1), Cd (0.006±0.002 to 0.018±0.002 mg L-1), Cr (0.027±0.001 to 0.074±0.001 mg L-1), Cu (0.016±0.002 to 0.033±0.001 mg L-1), Ni (0.031±0.001 to 0.053±0.002 mg L-1), Pb (0.050±0.002 to 0.092±0.001 mg L-1), and Zn (0.061±0.002 to 0.097±0.002 mg L-1). As, Ni and Pb recorded concentrations above their respective maximum permissible limits. Physicochemical parameters were appraised using the American Public Health Association standard method (APHA). The evaluation of the carcinogenic and non-carcinogenic health risks of the analyzed elements was carried out based on the guidelines of the USEPA. The hazard index values for children via upstream, midstream and downstream sample points were 0.0000128, 0.00000895 and 0.0513 respectively, while the hazard index values for adults via upstream, midstream and downstream sample points were 0.00000551, 0.00000395 and 0.00000581 respectively. The health risk estimation showed that the hazard quotients were within acceptable limits. The total cancer risks of potentially toxic elements were generally within the range of tolerable risk for adults and above the range of tolerable risk for children.
Mechanical and Microstructural Properties of AL 5754 Alloy Joined by GMAW and GTAW
Authors: AKÇAKALE Nürettin
Published: March 2021

The purpose of this study is to examine the effect of double pulse Gas Metal Arc Welding (GMAW) and Gas Tungsten Arc Welding (GTAW) on metal droplet transfer, weld bead geometry, weld pool profile and to examine the mechanical properties of the Al 5754 alloy weld joints. Al 5754-Al 5754 aluminum alloy plates were welded with ER 5356 welding wire. No significant defects were found, and full penetration joints were created. The effect of arc welding parameters on the speed and appearance of welding were investigated by means of macrostructure and microstructure characterization of fusion zone. Also, the characters of tensility and micro-hardness being of the welded specimens were measured.
Marrying an Orthodox tsarevna from Rome
Authors: Niţescu Iulia
Published: March 2021

This paper addresses the issue of Sofiia Palaiologina’s religious identity during her time in Moscow, by analyzing the Russian chronicles’ accounts of her marriage negotiations. It suggests that the official Muscovite account offered a carefully tailored narrative of a pious tsarevna as an attempt to explain why the grand prince negotiated the marriage with Rome, and to integrate Sofiia into the official Orthodox narrative of the dynasty. Although contradicted by her background and largely missing from other Russian accounts of the event, the Orthodox elements of Sofiia’s identity emphasized by the official chronicles have been interpreted as proof of the “Byzantine lineage” brought by her to Moscow. The local context, namely the opposition of metropolitan Filip and the current ecclesiastical debates, as well as Sofiia’s later image as “the Roman,” explain how this official narrative sought to appropriate Sofiia for Muscovite ideology.
MAKNA KANYOUKU ME (MATA) DALAM NOVEL KOIZORA KARYA MIKA
Authors: Sujarwo Okta Pratiwi Wijayanto , Khasanah Umul
Published: March 2021

Abstrak: Dalam berkomunikasi, masyarakat Jepang banyak menggunakan idiom. Idiom dalam bahasa Jepang disebut dengan Kanyouku. Menurut Sakata (1995:214) kanyouku adalah gabungan dua kata atau lebih yang maknanya dapat bermacam-macam, menerangkan arti masing-masing secara keseluruhan. Kurashina (2008: 3) menyatakan bahwa dalam Bahasa Jepang, idiom yang merujuk pada anggota badan ada banyak jumlahnya. Namun selain anggota badan, terdapat juga penggunaan idiom yang merujuk pada unsur hewan atau makanan. Penelitian ini menggunakan pendekatan kualitatif. Data yang digunakan dalam penelitian ini adalah kanyouku yang menggunakan kata me (mata) yang terdapat di dalam novel Koizora karya Mika. Metode yang digunakan untuk menganalisis data ialah metode deskriptif yang digunakan untuk menjelaskan makna leksikal dan makna idiom dari kanyouku yang menggunakan katame (mata) sehingga dapat diketahui makna darime (mata) dalam kanyouku tersebut. Dari 18 data kanyouku me (mata) yang dianalisis terdapat 6 kanyouku yang memiliki makna mata terbuka dan melihat, 1 kanyouku yang memiliki makna anggota tubuh yang mengecil mengekspresikan tersenyum, 2 kanyouku yang memiliki makna alat yang digunakan untuk menggambarkan suatu kejadian yang sudah diketahui atau sudah pernah terjadi, 1 kanyouku yang memiliki makna anggota tubuh yang digunakan untuk mengekspresikan kebahagiaan serta 8 kanyouku yang memiliki makna penglihatan atau pandangan.Kata kunci: Makna, Idiom (Kanyouku), Mata, Novel Abstract: In communicating, Japanese people use idioms a lot. Idioms in Japanese are called Kanyouku. According to Sakata (1995: 214) kanyouku is a combination of two or more words whose meanings can vary, explaining the meaning of each as a whole. Kurashina (2008: 3) states that in Japanese, there are many idioms that refer to limbs. But in addition to limbs, there is also the use of idioms that refer to elements of animals or food. This research uses a qualitative approach. The data used in this study is the kanyouku that uses the word me (eye) contained in Mika's Koizora novel. The method used to analyze the data is a descriptive method used to explain the lexical meaning and idiom meaning of kanyouku using katame (eyes) so that the meaning of darime (eyes) can be known in the kanyouku. From 18 data of kanyouku me (eyes) analyzed, there are 6 kanyouku that have the meaning of eyes open and seeing, 1 kanyouku which has a meaning of a shrinking body expressing a smile, 2 kanyouku which have meaning tools that are used to describe an event that is known or already ever happened, 1 kanyouku which has a meaning of a limb used to express happiness and 8 kanyouku which has a meaning of vision or sight.Keywords: Meaning, Idiom (Kanyouku), Eyes, Novels
ANALISIS ETIKA MORAL BUSHIDOU DALAM DORAMA REMAKE GREAT TEACHER ONIZUKA 2012 KARYA TORU FUJISAWA
Authors: Nurcahyono Dimas Putra Dewa Ari , Amalijah Eva
Published: March 2021

Abstrak: Terebi dorama adalah media yang dianggap tepat untuk disisipi nilai kebudayaan Jepang. Salah satunya adalah etika moral bushido. Penelitian ini fokus pada etika moral bushido  yang terdapat pada dorama Remake Great Teacher Onizuka 2012. Dalam penelitian ini fokus pada penggalian data yang berkaitan dengan permasalahan yang diajukan, yakni etika moral dalam dorama Remake Great Teacher Onizuka 2012. Pada penelitian ini, disimak isi cerita dalam dorama lalu mencatat kalimat pada dialog yang termasuk dalam etika moral bushido. Melalui pendekatan moral dan metode kualitatif, informasi yang didapat kemudian dikelompokkan dan dianalisis untuk ditarik kesimpulan. Hasil dari penelitian ini terdapat 5 etika moral bushido pada dorama Remake Great Teacher Onizuka 2012, yaitu etika moral keadilan, etika moral kebajikan, etika moral keberanian, etika moral kejujuran, dan etika moral kehormatan.Kata kunci: Etika Moral, Bushido, Drama Televisi Abstract: Terebi dorama is media that are considered appropriate to be inserted Japanese cultural values. One of them is bushido moral ethics. Focus of this research is bushido moral ethics that found in dorama Remake Great Teacher Onizuka 2012. In this research the writer tries to explore data relating to the problem raised, moral ethics analysis in dorama Remake Great Teacher Onizuka 2012. In this research, the writer listens contents of the story in the drama and then records the sentences in the dialogue which are included in bushido moral ethics. With moral approaches and qualitative methods, information obtained then grouped and then analyzed for conclusion. The results of this research can be concluded that there are 5 bushido moral ethics in dorama Remake Great Teacher Onizuka 2012, that is justice of moral ethics, virtue moral ethics, courage moral ethics, honesty moral ethics, honor moral ethics.Keywords: Moral Ethics, Bushido, Television Drama
JURNAL MEZURASHII 1(2) JANUARI 2019
Authors: Mezurashii Jurnal
Published: March 2021

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ANALISIS PENGGUNAAN ALIH KODE DAN CAMPUR KODE DALAM LIRIK LAGU AIMER ALBUM DAWN DAN SLEEPLESS NIGHTS
Authors: Yuana Cuk
Published: March 2021

Abstrak: Penelitian ini bertujuan untuk mendeskripsikan alih kode dan campur kode yang terdapat dalam lirik lagu  Aimer album Dawn dan Sleepless Nights. Metode yang digunakan adalah metode deskriptif kualitatif, yaitu penelitian yang mengandalkan uraian berupa lirik lagu. Dalam lirik lagu  Aimer album Dawn dan Sleepless Nights  menunjukkan bahwa terdapat alih kode ekstern (outer code switching) dari bahasa Jepang ke bahasa Inggris. Adapun bentuk campur kode yang terdapat adalah campur kode ekstern (outer code switching) dalam wujud frasa, kata, dan kalimat.Kata kunci: Sosiolinguistik, dwibahasa, alih kode, campur kode, lirik lagu  Abstract: This study aims to describe the code switching and code mix contained in the lyrics of the song Aimer album ‘Dawn’ and ‘Sleepless Nights’. The method used in this study is a qualitative method, a research that relies on the description in the form of song lyrics. In the lyrics of the song Aimer album ‘Dawn’ and ‘Sleepless Nights’ shows that there is an external code switching from Japanese to English. Whereas the mixed form of code contained is a mixture of external code in the form of phrases, words, and sentences. Keywords: Sociolinguistics, bilingual, code switching, code mixing, song lyrics
ANALISIS GAYA BAHASA PADA SLOGAN KEMASAN MAKANAN PRODUK JEPANG
Authors: Mustika Laras Dian , Hasanah Luluk Ulfa
Published: March 2021

Abstrak: Penelitian ini bertujuan untuk mendeskripsikan gaya bahasa yang digunakan pada kemasan makanan produk jepang. Selain itu juga bertujuan untuk menggali makna yang terkandung dalam slogan kemasan makanan. Data penelitian berupa frasa, kalimat, dan gambar yang ditemukan pada kemasan makanan. Data dianalisis dengan menggunakan analisis deskriptif kualitatif. Hasil penelitian menunjukkan bahwa gaya bahasa yang terdapat pada slogan kemasan makanan produk jepang dibedakan atas empat gaya bahasa, yaitu gaya bahasa hiperbola, personifikasi, paralelisme, dan preterito. Selain itu, juta terdapat makna semantik yang terkandung pada slogan-slogan tersebut.Kata kunci: Gaya Bahasa, Slogan Makanan, Makanan Produk Jepang Abstract: This study aims to describe the style of language used in Japanese food packaging. It also aims to explore the meaning contained in the slogan of food packaging. Research data in the form of phrases, sentences, and images found on food packaging. Data were analyzed using qualitative descriptive analysis. The results showed that the style of language contained in the slogan of food packaging Japanese products are divided into four language styles, namely hyperbole, personification, parallelism, and preterito. In addition, there are million semantic meanings contained in these slogans. Keywords: The Style of Language, The Slogan of Food, Japanese Food Packaging