bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrin Trafficking, Fibronectin Architecture, and Glomerular Injury upon AdipoR1 Depletion
Authors: Lindfors Sonja , Schmotz Constanze , Lewandowski Dominik , Hau Annika , Saikko Leena , Lehtonen Eero , Majaniemi Ville , Karhe Minna , Naams Jette-Britt , Nisen Harry , Tienari Jukka , Saleem Moin A. , Pfeil Katharina , Bugger Heiko , Pietiläinen Kirsi H. , Mirtti Tuomas , Palczewski Krzysztof , Lehtonen Sanna
Published: January 2025

Background:

Deficiency of adiponectin and its downstream signaling may contribute to the pathogenesis of kidney injury in type 2 diabetes. Adiponectin activates intracellular signaling via adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2), but the role of AdipoR-mediated signaling in glomerular injury in type 2 diabetes remains unknown.

Methods:

The expression of AdipoR1 in the kidneys of people with type 2 diabetes and the expression of podocyte proteins or injury markers in the kidneys of AdipoR1-knockout (AdipoR1-KO) mice and immortalized AdipoR1-deficient human podocytes were investigated by immunohistochemistry and immunoblotting. The functional role of AdipoR1 was studied in AdipoR1-deficient podocytes by performing assays for apoptosis, cytokine secretion, mechanical stress, adhesion, and endocytic trafficking.

Results:

Glomerular AdipoR1 expression was lower in type 2 diabetes and associated kidney disease, correlating with higher BMI and podocyte loss. Male AdipoR1-KO mice showed typical signs of early diabetic kidney disease, including albuminuria, glomerular structural abnormalities, and lower expression of central podocyte proteins; females were less affected. Podocyte apoptosis increased in female and male AdipoR1-KO mice and excessive podocyte loss, potentially due to detachment, was detected in males. AdipoR1 deficiency impaired the YAP-mediated mechanoresponse and induced accumulation of the extracellular matrix (ECM) protein fibronectin in the glomeruli in vivo, and podocytes in vitro. Functionally, AdipoR1 deficiency impaired endocytosis of the ECM receptor active integrin β1, disturbed focal adhesion turnover, and remodulated podocyte-derived ECM, thereby reducing podocyte adhesion.

Conclusions:

AdipoR1 deficiency in mice resulted in the development of kidney injury predominantly in males. Mechanistically, AdipoR1 loss in podocytes impaired endocytosis of active integrin β1, which plausibly compromised focal adhesion dynamics, disturbed fibronectin matrix turnover, and hindered podocyte adhesion.
Hiatus from Old Irish to Modern Scottish Gaelic, Irish and Manx
Authors: Hughes Art
Published: January 2025

Hiatus, or diaeresis, refers to two vowel sounds in adjacent syllables. In addition to highlighting the survival of hiatus from Old Irish texts into Scottish Gaelic, vis-à-vis its absence in Manx and Modern Irish, a further major consideration of the current paper will
be an analysis of the percentage survival rate of Old Irish hiatus in modern Scottish Gaelic dialects (§25).
Montaje en articulador semiajustable
Authors:   Universidad Cooperativa de Colombia, Restrepo Villamizar Claudia Elena
Published: January 2025

El objetivo de esta guía es aportar al conocimiento de los aspirantes al programa de Odontólogos, mostrando de forma detallada el procedimiento del montaje del articulador semiajustable después de la toma de relación bicondilo-maxilar. Esto permitirá dar al paciente un diagnóstico, un pronóstico y un plan de tratamiento.
Kartal
Authors: Tarbay János Gábor
Published: January 2025

In 2019, a new Late Bronze Age (LBA) assemblage from Völgy-dűlő at Kartal (Pest County) was added to the number of bronze hoards excavated in the framework of community archaeological programmes in Hungary. This unique assemblage was deposited beneath two fragments of a pot, originally arranged regularly. The Carpathian Basin-style objects in the Kartal hoard date to several periods from Br D to Ha B1; based on their typo-chronological analysis, their deposition may have taken place in the latter. The chronological characteristics of the Kartal find, a deposition comprising old-style jewellery, suggest the assemblage is a multi-period hoard. The signs of use, essentially abrasions and microwear traces, also indicate that some objects had been used even for a relatively long time before deposition. The breaking of the deposited ingots and bronze objects was deliberate and probably did not occur simultaneously, and most of these finds were still usable preceding their breaking. The Kartal hoard may have been deliberately assembled by a small community. The hoarded objects may represent different aspects of a Bronze Age community, who, according to our current knowledge of the topography of the era, deposited their votive assemblage far from any LBA settlements.
New specimen of an Early Iron Age brooch type from Western Transdanubia
Authors: Ilon Gábor
Published: January 2025

The museum obtained the two-loop nodular (or knobbed) bow brooch, a stray find, in 1970. The jewellery, 66 mm long and weighing 22.6 g, is still in good condition today. Its shape is a mixture of Types 6a and 6d in Stane Gabrovec’s system, which were in vogue in the Ha C1–2 phases, i.e., from the mid-8th to the mid-7th centuries BC. In lack of a find context and accompanying finds, the artefact in focus cannot be dated more precisely within this period; the topographical position of its findspot fills an empty area in the foregrounds of the Eastern Alps.
Preliminary report on the excavations of the legionary bath of Brigetio in 2024
Authors: Bartus Dávid , Szabó Melinda , Olasz Rita Helga , Müller Ákos , Simon Bence , Juhász Lajos , Lenár Vilmos , Borhy László , Számadó Emese
Published: January 2025

The excavation of the legionary camp at Brigetio began in 2021. Throughout the last four campaigns, 2,200 square meters of the baths were unearthed, which span a total of well over 6,000 square meters. In 2024 the work continued across four surfaces. The excavations here shed a light on the size of the bath, which extended westward over a much larger area than previous excavations and radar surveys had suggested. In connection with the heating systems of the baths, two praefurnia preserved in excellent condition, along with their two adjoining service rooms, were also unearthed. In the southern section of the baths, three lime slaking pits were discovered, a rare occurrence in military context within the Roman Empire.
RETHINKING AND TRANSFORMATION OF ANCIENT PAGAN IMAGES, SCENES AND THEMES IN EARLY CHRISTIAN ART
Authors:   St. Tikhon's Orthodox University of Humanities, Suslenkov Vitaly Е.
Published: January 2025

The article is a generalization of the main ways in which both spontaneous and custom adaptation and transformation of images and scenes of ancient pagan subjects took place in Early Christian art. Many of them are borrowings from the old repertoire due to the proximity of the theme and similarity of content (especially in funeral ensembles), some have been completely reinterpreted in line with the interpretatio christiana. The ancient traditions of the ancient art school and its techniques became the basis for the processing of old schemes into new compositions of a different content (while preserving the ancient meaningful elements). In addition, pagan images — in line with both the rhetorical tradition and the religious philosophy of Neoplatonism — have been preserved in the Christian context as allegories and personifications of abstract forces and properties of nature, virtues. In parallel, a number of pagan heroes who had a cult in antiquity, in their canonical images and in mythological scenes, came to the new world as an allegory about the properties of the world related to Christian ideas — the ideas of moral virtue, resurrection, immortality (this aspect is not usually considered by researchers of Early Christian art). This is confirmed by the direct proximity of some pagan heroes and Christian symbols and images. An important role in the processes of adapting the images of departing cults was played, against a generally negative background to pagan teachings, by the attitude of Christian writers to the wisdom and moral examples of antiquity as signs of God’s participation in history.
PASTIGLIA OR “GYPSUM RELIEF” IN THE DECORATION OF SACRED IMAGES
Authors:   State Museum of Fine Arts of the Republic of Tatarstan, Lysenko Oksana A.
Published: January 2025

The attire of sacred images from pastiglia is an original phenomenon that has not yet received special research in Russian art history. The article analyzes works from different eras; it examines the technological and artistic features of pastiglia, which has been used in Italy, Cyprus and Sinai since the 13th century. Some scholars believe that pastiglia, like gesso carving, was merely an imitation of metal frames. One of the main objectives of our scientific work was to prove the unfairness of such an opinion. The most important objective was the study of Russian monuments decorated with pastiglia. Until recently, experts associated decoration made using this technique with late renovation works of the 19th century. Research of the icon “Tsar of Tsars”, 1680s — early 1700s, from the Trinity Church of the women’s monastery of John the Baptist in Sviyazhsk, kept in the State Museum of Fine Arts of the Republic of Tatarstan, allows us to refute this opinion. The relief pattern of this icon dates back to the time of its writing and is part of the original concept. This conclusion is supported by the X-ray fluorescence analysis of samples of material from the relief pattern, the crown of Christ and the gesso on the board of the Sviyazhsk work. Unlike frames, pastiglia decoration was made directly on the icon and is therefore integral to it. The article raises the issue of the preservation of late relief decorations that have artistic and historical-cultural significance, but are sometimes destroyed by restorers in order to discover paintings. In addition, the work touches on the current problem of terminology.
Los álbumes ilustrados de Raquel Díaz Reguera: Itinerario lector imprescindible para la educación en valores / Raquel Díaz Reguera’s illustrated albums: an essential reading itinerary for education in values
Authors: Llamas Martínez Isabel , Quiles Cabrera María del Carmen , Núñez Molina Gabriel
Published: January 2025

This article focuses on an approach to the figure of Raquel Díaz Reguera in the extensive field of contemporary children’s literature, highlighting the importance and value that the illustrated album acquires, not only as a means of artistic expression, but also for its role in literary education and the transmission of values. Through a qualitative description of her career as a creator within this genre, we will highlight the author’s commitment to themes of great social and educational importance. Emotional and affective development, gender roles, diversity and peaceful coexistence are some of the topics addressed in her titles. After an approach to the album genre, we will focus on the production of Díaz Reguera, so as to offer a reading itinerary through a selection of various valid titles that will help us forge a literary education that, at the same time, guarantees not only emotional stability, but also the creation of civic awareness and social commitmentl.
Varoluşun Derinliklerini Sanat Yoluyla Ortaya Çıkarmak: Philip Guston Örneği
Authors: Göktepeliler Ömür , Kurt Betül
Published: January 2025

Bu makale, Amerikalı ressam Philip Guston’ın serilerini varoluşsal temalar bağlamında ele almaktadır. Philip Guston'ın serileri genel olarak, Amerikan toplumundaki ırkçılık, bağnazlık ve sosyal adaletsizliğin bir incelemesi olarak değerlendirilmektedir. Çalışma, Guston’ın kişisel ve siyasi kimliğinin sanatındaki dönüşümü nasıl etkilediğini ve bu dönüşümün sanat tarihinde nasıl bir yer edindiğini ortaya koymayı amaçlamaktadır. Çalışmada, Guston’ın eserlerinin estetik ve felsefi boyutları, sanat tarihindeki konumu ve toplumsal mesajları detaylı bir şekilde ele alınmaktadır. Yapılan bu araştırmada nitel araştırma yöntemlerinden literatür tarama yapılmış ve eser inceleme yöntemi ile eserler, estetik özellikleri, kullanılan teknikler, tarihi bağlam ve Guston’ın kişisel yaşamı göz önünde bulundurularak incelenmiştir. Bu makale, Philip Guston’ın sanatsal çalışmalarını, sanatın toplumsal adaletsizlikle yüzleşme ve bu sorunlara meydan okuma aracı olabileceğini gösteren önemli bir örnek olarak değerlendirirken, sanatçının eserlerinin sadece sanatsal açıdan değil, aynı zamanda toplumsal mesajlar taşıyan eleştirel bir duruşa sahip olduğunu da vurgulamaktadır. Sonuç olarak Philip Guston’ın sanatsal çalışmaları, sanatın toplumsal adaletsizlikle yüzleşme ve meydan okuma gücünü gösteren önemli bir referans niteliğindedir.
Polyphenol-Rich Extract of Roselle Improves Oxidative Stress Status, Renal Function and Structure of Diabetic Rat
Authors: Mohammed Yusr Fatima , Jubaidi Fatin Farhana , Ismail Sumayyah Binti , Budin Siti Balkis
Published: January 2025

Diabetic nephropathy is a progressive chronic renal disease, that leads to renal failure mediated by oxidative stress. Roselle or Hibiscus sabdariffa is well-known for its health benefits and is rich in polyphenols with high antioxidant activities. Limited studies evaluate the effects of polyphenol-rich extract of roselle (HPE) on the development of diabetic nephropathy. Hence, this study aimed to determine the effect of HPE in the renal of diabetic rats focusing on oxidative stress, renal function, and structural changes. Type 1 diabetes mellitus was induced in adult male Sprague-Dawley rats which were then divided into three groups: untreated diabetes (DM), HPE-supplemented diabetic rats (DM+HPE), and metformin-treated diabetic rats (DM+MET). Non-diabetic rats (NDM) served as normal controls. All rats were left untreated for four weeks followed by another four weeks of treatment, respectively. At the end of the study, all rats were sacrificed whereby blood was collected for creatinine level analysis, and kidneys were collected for oxidative stress and antioxidant markers as well as histological analyses. Data showed that HPE reduced blood glucose and creatinine levels significantly and improved catalase (CAT) activity. HPE supplementation also reduced the lipid and protein oxidation process, marked by significant reductions in malondialdehyde (MDA) and advanced oxidation protein products (AOPP). Moreover, HPE supplementation improved renal structure, especially in reducing glomerulus degeneration and renal tubule damage. In conclusion, this study suggests that HPE is able to reduce renal damage by mitigating oxidative stress and improving antioxidant status that potentially prevents the progression of diabetic nephropathy in diabetic rat model.
Language mask in modern social communication: media sphere
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Shulinova Larysa
Published: January 2025

Modern media communication as a component of society requires systematic research (especially the linguistic one) of the self-realization's possibilities of the person because the combination of the verbal and non-verbal components is the basis of media texts of various types and genres. The concepts of "personality type", "mask", "social mask", "media mask", "language mask" are considered within using of different criteria for their interpretation, where the language component is mostly optional and unrepresentative. The article focuses on the actualization of the language level for a more detailed scientific analysis in concepts, terms and approaches to investigation that are correlated with the requirements of nowadays. The actual definition of a mask in media communication is formulated. It is a social perception of person, that is modeled by an individual using verbal and non-verbal means in accordance with own intentions and / or requests of society or its individual groups. An own approach to the classification of language masks in the media is proposed according to verbal (systematically used language units of different levels to implement the goals and tasks of communication) and non-verbal (personality types from the point of view of psychology, language, style, genre functions) criteria. The conducted research gave grounds to distinguish the following language masks in the media: Intellectual, Informant, Advisor, Expert, Showman / Showwoman, Simpleton, Rebel, Provocateur, Caregiver, Sympathizer. The main language means for each of the masks are outlined, and for illustration, individual persons who carry these masks are named. It is emphasized that the proposed classification is an open system that should be considered as a starting model, that is characterized by variability (addition, deletion, modification), due to the development of social communication and information technologies, the needs of society, its individual groups and personalities. The prospects for further research are also outlined: more detailed analysis of the stated language markers, their expressive and influential potential, evolution of both individual language masks in the media and the personalities who use them, and clarification of the specifics of the different masks' coexistence in the communication of one person.
Reconstruction full-thickness defect of calcaneus post trauma using sural fascio-cutaneous flap: a case report
Authors: Hotiatun  , Sungkar Amru , Aryani Bertina Surya
Published: January 2025

Traffic accidents often cause degloving injuries to the extremities that can cause an avulsion of the skin. Injuries of the feet and lower legs require special management, specifically the calcaneus region, which is an anatomical challenge for reconstructive surgery. The sural flap is often used for calcaneus defect reconstruction. This method provides more volume compared to skin graft methods. We report the case of a 33-year-old woman who was injured in a motorcycle accident. The patient had a wound on the calcaneus about 8 cm×3 cm long, just below the medial malleolus. The wound is circular, leaving intact tissue as a pedicle with a plantar pedis measuring 3 cm×2×cm×1 cm. The patient underwent debridement with a sural flap. Follow-up post-surgery, the flap was viable, but other procedures (casting, in setting flap, and refinement flap) are still needed to achieve better outcomes and physiotherapy to restore function. Degloving injuries generally cause devascularization. In cases like this, debridement is used as the initial therapy to preserve the surrounding soft tissue and skin. The second treatment is to prevent contractures. Most surgeons recommend a skin graft in the first stage. We performed a flap that has a rapid reconstruction process and can prevent the risk of skin necrosis as a weight-bearing area. Due to the existence of a long, retractable vascular pedicle, the sural flap is a helpful treatment in the reconstruction of skin defects in the distal area of the lower extremity. Reconstruction using fasciocutaneous flap procedure, for the patient's lower extremity defect (calcaneal defect) was successful. In trauma cases that cause damage full full-thickness skin and soft tissue, it is advisable to perform a flap as one of the reconstructive surgery procedures to restore the best function and shape of the involved lower extremity.
Museo Virtual de Matemáticas UIS. Disecciones Geométricas y Fractales
Authors: Granados Pinzón Claudia Inés , Acevedo Rincón Jenny Patricia
Published: January 2025

Desde hace diez años, en la Universidad Industrial de Santander, se han empleado herramientas digitales de geometría dinámica para mejorar la comprensión y el aprendizaje de conceptos y problemas geométricos. Recientemente, nos enfrentamos al desafío de explorar temas aplicados a la geometría, entre ellos están las disecciones geométricas y los fractales. Como resultado de esta iniciativa, creamos una actividad virtual de extensión accesible para todos los estudiantes, conocida como Museo Virtual de Matemáticas UIS.
Formación Docente: Herramientas Didácticas en Lengua Extranjera como Innovación Educativa
Authors: Jiménez Chaparro Andrea
Published: January 2025

La formación docente en herramientas didácticas en lengua extranjera, como innovación educativa desarrollada con docentes de la Escuela de Trabajo Social, representa el interés de las direcciones de Escuela y del Instituto de Lenguas en establecer alianzas estratégicas para fomentar procesos de formación en metodología, pedagogía y didáctica que conduzcan a la innovación educativa en las aulas.
„Ster. Organ równouprawnienia kobiet” pod redakcją Pauliny Kuczalskiej-Reinschmit i Józefy Bojanowskiej Warszawa 1907–1914 (z antologią i bibliografią zawartości)
Authors: Zawiszewska-Semeniuk Agata
Published: January 2025

„Rudder. The organ of women’s suffrage”, edited by Paulina Kuczalska-Reinschmit and Józefa Bojanowska. Warsaw 1907–1914 (with anthology and bibliography of contents)
The monograph is a continuation and complement to the book entitled ‘The Rudder’, edited by Paulina Kuczalska-Reinschmit. Lvov 1895–1897 (with an anthology and bibliography of contents) [Wydawnictwo Naukowe Uniwersytetu Szczecińskiego, Szczecin 2017].
Part one is a description of: the state of research on the ‘The Rudder. The organ of women’s suffrage’ [„Ster. Organ równouprawnienia kobiet”], the political situation in the Polish lands under the Russian partition after the revolution of 1905–1907, and the programme of the Union of Polish Women’s Equal Rights [Związek Równouprawnienia Kobiet Polskich] (1907–1921) and the periodical ‘The Rudder’ [„Ster”] (1909–1914) – led by leaders of Polish suffragettes: Paulina Kuczalska- -Reinschmit (1859–1921) and Józefa Bojanowska (1873–1945).
Part two is an anthology of the most interesting – from the point of view of contemporary readers – texts published in the pages of ‘The Rudder’: articles, polemics, reviews, letters, fiction.
The third part is a bibliography of ‘The Rudder’ content.
Labor Relations Change in Conditions of Information Economy Development
Authors:   Saratov State University, Krasilnikov O. Y.
Published: January 2025

In the article there are considered theoretical aspects of labor relations in modern conditions of information economy. The author pays attention to modification of labor character, forms of labor activity coordination and informational product property relations.
Resource Security of Agrarian Sector of Economy of Russia
Authors:   Institute of Agrarian Problems of RAS, Potapov A. P.
Published: January 2025

In clause the condition of resource potential of agrarian sector of economy of Russia is analyzed, influence of factors of foreign market on structure of use of resources in agriculture is investigated; offers on increase of resource security of agrarian production are given.
Customer Perspective Towards Secondhand Clothing and Its Impact on Customer's Loyalty: The Mediating Role of Customer Satisfaction
Authors: Adji Janice Felicia De Sinta , Susilowati MG Westri Kekalih
Published: January 2025

This research explores how customer perception of critical, hedonic, economic, and virtuosity could affect their satisfaction and ultimately lead to repurchase intentions. Many businesses are working on converting themselves into sustainable businesses to contribute to the circular economy. Green marketing is a method that business owners can use to help their businesses become sustainable. A quantitative Structural Equation Modelling (SEM) approach was used to investigate the relationship among the variables modeled. This study covered 125 respondents as primary data resources. Questionnaires designed on a 1-5 Likert scale were used to collect the data. The results show that critical and hedonic aspects insignificantly influence customer satisfaction when wearing thrift fashion.
Meanwhile, economics and virtuosity positively influence customer satisfaction when they wear Tthrift fashion. Customer satisfaction positively impacts and mediates the influence of loyalty, which is one of the other indicators. The study contributes to understanding customer behavior toward secondhand products to develop strategies for enhancing customer satisfaction toward loyalty.
Obstáculos epistemológicos e a Educação Ambiental Transformadora
Authors: Carvalho Juliana Barros , Aguiar José Vicente de Souza
Published: January 2025

A crise ambiental indica a necessidade de mudança de comportamento, valores e atitudes humanas. É fundamental um afastamento das ideias, simplistas e reducionistas, relativas às complexas relações que ocorrem no ambiente, que a Educação Ambiental se aproxime do ponto de vista crítico. O artigo tem como objetivo compreender as contribuições de Bachelard para a promoção da Educação Ambiental transformadora, considerando a superação de alguns obstáculos epistemológicos presentes no modelo dominante. Dessa forma, com o intuito de promover a discussão sobre a complexidade da Educação Ambiental e a necessidade de mudanças de concepções, buscou-se realizar uma pesquisa bibliográfica sobre a Educação Ambiental conservadora e transformadora; as rupturas e obstáculos epistemológicos propostos por Bachelard em seu livro “A formação do Espírito Científico”,  instrumento de pesquisa deste trabalho. Discute-se alguns obstáculos epistemológicos relevantes para a temática estudada, são eles: a experiência primeira, o conhecimento geral, o obstáculo verbal, o substancialismo, e o conhecimento unitário e pragmático. Os conhecimentos enraizados na sociedade, como aqueles relacionados à cultura antropocêntrica, aliados a um conhecimento simplista e superficial do ambiente e suas relações, são obstáculos epistemológicos para a reconstrução de conceitos e valores, que impossibilitam a evolução de sujeitos participativos nos processos sociais e o exercício da cidadania. Para superar os obstáculos é necessário ter consciência da existência deles, compreender os fenômenos estudados, não se limitando a explicações superficiais, e sim, buscar refletir sobre as questões levantadas.
Analysis of Marketing Activities of a Trading Company – Nochem Sp. z o.o
Authors: Grzegorczyk Wojciech
Published: January 2025

The purpose of the paper is to present the profile of the chemical and cosmetic products wholesaler "Hurtownia Nochem Sp. z o.o.". The scope of activity of the wholesaler, its most important current problems, marketing activities undertaken, as well as sales and financial results achieved by the wholesaler, which are the consequence of decisions made in the field of company management in a 3-year time perspective, were presented. The analysis of the case study may motivate to seek answers to questions about possible directions of development of this organization.
Vers l'égalité de genre dans les systèmes fiscaux et budgétaires : dépasser le cadre des biais implicites et explicites
Authors: Grown Caren , Mascagni Giulia
Published: January 2025

Le thème du genre et de la fiscalité est de plus en plus présent dans les groupes de décideurs politiques publiques. La plupart des résultats existants sont basés sur le cadre des biais implicites et explicites développé au milieu des années 1990. Ce cadre a été utile pour promouvoir à la fois la recherche dans ce domaine et les réformes fiscales visant à lutter contre les biais de genre. Cependant, les biais explicites devenant de plus en plus rares, nous soutenons que ce cadre n'est plus adapté pour guider les décisions politiques vers une meilleure équité fiscale et égalité de genre. Plus important encore, le terme même de « biais fiscal » donne l'impression que la solution pour rectifier le problème sous-jacent réside dans la réforme du système fiscal uniquement. Nous proposons une approche alternative qui se base sur l’objectif politique d’une égalité de genre, dans la perspective d'un programme de politique budgétaire féministe au sens large. Cette approche soutient également une politique fiscale progressiste et un programme de réforme administrative qui génère des recettes suffisantes pour financer les politiques publiques pour l’égalité de genre, tout en recherchant l'équité fiscale.
Pembelajaran Pendidikan Agama Islam dan Problematikanya di Sekolah Umum dalam Penerapan Kurikulum Merdeka
Authors: Singgih Caesar Putro Prakoso  , Endis Firdaus  , Saepul Anwar
Published: January 2025

Penelitian ini bertujuan untuk mengeksplorasi problematika dalam pembelajaran Pendidikan Agama Islam (PAI) di sekolah umum, khususnya dalam penerapan Kurikulum Merdeka. Penelitian ini menggunakan pendekatan kualitatif dengan teknik pengumpulan data wawancara, observasi, dan analisis dokumen. Subjek penelitian terdiri dari guru dan siswa SMP Negeri 47 Bandung dan SMP Muhammadiyah 2 Bandung. Hasil penelitian menunjukkan bahwa meskipun Kurikulum Merdeka memberi ruang bagi kreativitas dan pendekatan berbasis proyek, penerapannya dalam PAI terbentur pada kesulitan menghubungkan konsep-konsep agama dengan praktik sehari-hari siswa. Selain itu, faktor keterbatasan infrastruktur dan dukungan sumber daya juga mempengaruhi efektivitas pembelajaran. Namun, beberapa strategi penyesuaian yang diterapkan oleh guru, seperti mengintegrasikan pembelajaran berbasis proyek dengan pendekatan konvensional, serta melibatkan orang tua dalam pembelajaran, menunjukkan dampak positif terhadap motivasi siswa. Penelitian ini diharapkan dapat memberikan wawasan lebih dalam mengenai tantangan dan solusi yang dapat meningkatkan kualitas pembelajaran Pendidikan Agama Islam dalam Kurikulum Merdeka.
Pembinaan Akhlak Siswa Melalui Ekstrakurikuler Kelompok Remaja Masjid
Authors: Achmad Ghiyats Setiawan  , Udin Supriadi  , Mulyana Abdullah
Published: January 2025

Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang memengaruhi kinerja program ekstrakurikuler keagamaan yaitu Kelompok Remaja Masjid (KRM). Jenis penelitian ini adalah kualitatif dengan pendekatan studi kasus. Data dikumpulkan melalui wawancara, observasi, dan dokumentasi. Kemudian data dianalisis dengan reduksi data, penyajian data, dan penarikan kesimpulan.  Hasil penelitian menunjukkan bahwa ekstrakurikuler KRM memiliki tujuan utama yaitu untuk memperdalam pemahaman agama dan membentuk karakter siswa. Selain itu, Ekstrakurikuler KRM juga memiliki peranan krusial dalam pengembangan akhlak siswa dengan menanamkan nilai-nilai seperti disiplin, solidaritas, kepemimpinan, dan tanggung jawab. Namun, terdapat tantangan seperti keterbatasan dana dan dampak negatif dari media sosial yang dapat menghambat pencapaian tujuan tersebut sama. Walaupun demikian, melalui berbagai program KRM, diharapkan dapat memperkuat karakter keimanan dan ketakwaan siswa, serta menumbuhkan sikap akhlak yang baik sesuai ajaran Islam. Keberhasilan program ini sangat bergantung pada dukungan sumber daya yang tersedia dan kemampuan untuk beradaptasi dengan perubahan lingkungan, sehingga siswa dapat berkembang secara maksimal dalam aspek spiritual dan moral.
Uji N-Gain pada Efektivitas Penggunaan Game dengan Strategi SGQ untuk Meningkatkan Berpikir Komputasi dalam Literasi Energi
Authors: Harianja M Rokhati , Yusup Muhamad , Sardianto Markos Siahaan
Published: January 2025

Penelitian ini bertujuan menganalisis efektivitas penggunaan pembelajaran berbasis game dengan strategi SGQ (Student Generated Question) untuk meningkatkan berpikir komputasi dalam literasi energi. Penelitian ini menggunakan desain kuasi-eksperimental, di mana siswa dibagi menjadi kelompok eksperimen dan kontrol. Skor pre-test dan post-test dikumpulkan dan dianalisis menggunakan perhitungan N-Gain untuk menentukan tingkat peningkatan hasil belajar. Hasil penelitian menunjukkan bahwa kelompok eksperimen yang mengikuti strategi SGQ dalam konteks gamifikasi memperoleh skor N-Gain yang secara signifikan lebih tinggi dibandingkan kelompok kontrol. Secara khusus, kelompok eksperimen mencapai rata-rata skor N-Gain sebesar 0,64, yang diklasifikasikan sebagai peningkatan sedang hingga tinggi, sedangkan kelompok kontrol mencatat rata-rata skor N-Gain yang lebih rendah sebesar 0,30, mencerminkan peningkatan yang terbatas. Analisis tingkat peningkatan menunjukkan bahwa 80,56% siswa dalam kelompok eksperimen berada dalam kategori "sedang", sedangkan 16,67% mencapai peningkatan "tinggi". Sebaliknya, kelompok kontrol sebagian besar berada 50 % di kategori "rendah".  ,44,44 % sedang dan Cuma 5,6 % tinggi. Temuan ini menunjukkan bahwa pendekatan permainan berbasis strategi SGQ efektif dalam mendukung berpikir komputasi dalam konteks literasi energi. Penelitian ini menyimpulkan bahwa pengintegrasian strategi pembelajaran berbasis permainan dan strategi  SGQ, dapat meningkatkan keterlibatan dan pemahaman siswa terhadap konsep yang kompleks, sehingga menawarkan metode yang menjanjikan untuk meningkatkan hasil belajar di bidang yang membutuhkan pemahaman konseptual dan pengembangan keterampilan.
Hasil Belajar: Korelasi Kuantitatif antara Self Efficacy dan Kebiasaan Belajar
Authors: Desmala Eliza  , Nurul Azizah  , Sa’idy  , Umi Hijriyah  , Agus Susanti
Published: January 2025

Penelitian ini bertujuan untuk membuktikan sejauh mana keterkaitan atau hubungan self efficacy dan kebiasaan belajar dengan hasil belajar PAI di SMP Negeri 22 Bandar Lampung. Jenis penelitian ini adalah penelitian kuantitatif dengan pendekatan korelasional. Penelitian ini menggunakan desain Ex-post facto. Untuk mengumpulkan data, digunakan instrumen tes dan non-tes untuk mengukur self efficacy, kebiasaan belajar, dan hasil belajar PAI peserta didik. Analisis data dilakukan dengan uji normalitas, uji linieritas, uji heteroskedastisitas, uji multikolonieritas, uji koefisien determinasi, uji T, dan uji F. Hasil penelitian menunjukkan bahwa tidak ada pengaruh signifikan antara self efficacy dan kebiasaan belajar terhadap hasil belajar PAI peserta didik di SMP Negeri 22 Bandar Lampung pada tahun ajaran 2024/2025. Berdasarkan uji F, nilai signifikansi sebesar 0,562 lebih besar dari 0,05, yang berarti bahwa self efficacy dan kebiasaan belajar tidak memengaruhi hasil belajar. Selain itu, berdasarkan uji koefisien determinasi, nilai R square sebesar 1,5%, yang menunjukkan bahwa 98,5% hasil belajar dipengaruhi oleh faktor lain.
THE ROLE OF ENGLISH IN CAREER READINESS FOR FUTURE TEACHERS [PERAN BAHASA INGGRIS DALAM KESIAPAN KARIR GURU MASA DEPAN]
Authors: Rompis Joanne Hyatt May , Sumbung Calvin , Indriani, M.Pd. Siane
Published: January 2025

As the world becomes more connected, being proficient in English is crucial for teachers' career readiness and professional growth. For future teachers, having strong English skills can open numerous opportunities. This study explores the role of English language proficiency in preparing future teachers for their careers. The researchers used a mix of qualitative and quantitative methods, including interviews with students who are preparing themselves to become teachers. The findings highlight that English is the global language of communication and learning. Teachers who are fluent in English can better access educational resources, collaborate with colleagues worldwide, and foster intercultural understanding in their classrooms. Mastering the four basics of English skills, reading, writing, listening, and speaking is the key to equipping future teachers with the competencies they need to succeed. By improving their English skills, future educators can thrive in an increasingly globalized world.
Abstrak bahasa Indonesia 
Seiring dengan semakin terhubungnya dunia, menguasai bahasa Inggris sangat penting bagi kesiapan karier dan pertumbuhan profesional guru. Bagi calon guru, memiliki keterampilan bahasa Inggris yang baik dapat membuka banyak peluang. Studi ini mengeksplorasi peran kemahiran bahasa Inggris dalam mempersiapkan calon guru untuk karier mereka. Para peneliti menggunakan campuran metode kualitatif dan kuantitatif, termasuk wawancara dengan siswa yang belajar untuk menjadi guru. Temuan tersebut menyoroti bahwa bahasa Inggris adalah bahasa komunikasi dan pembelajaran global. Guru yang fasih berbahasa Inggris dapat mengakses sumber daya pendidikan dengan lebih baik, berkolaborasi dengan rekan kerja di seluruh dunia, dan menumbuhkan pemahaman antarbudaya di kelas mereka. Menguasai empat keterampilan dasar bahasa Inggris - membaca, menulis, mendengarkan, dan berbicara adalah kunci untuk membekali calon guru dengan kompetensi yang mereka butuhkan untuk berhasil. Dengan meningkatkan keterampilan bahasa Inggris mereka, calon pendidik dapat berkembang pesat di dunia yang semakin mengglobal.
Effect of hydroelectrolytic beverages on the roughness and microhardness of bulk fill resin composites
Authors: Scatolin Renata Siqueira , Grigoletto Caio Castro , Ferraz Laura Nobre , Vitti Rafael Pino
Published: January 2025

Aim: This study aimed to assess the effects of a hydroelectrolytic beverage on the surface roughness and microhardness of different bulk fill resin composites. Methods: Sixty resin composite samples were prepared and divided into three groups: FiltekTM Z350 (C), FiltekTM One Bulk Fill (BF-F), and Opus Bulk Fill APS (BF-O). These were further subdivided to analyze two beverage groups: GatoradeTM Lemon (GL) and distilled water (control). Surface roughness (Ra), surface microhardness (KHN), and scanning electron microscopy (SEM) results were evaluated (n=10). The data were subjected to two-way ANOVA (for roughness) or three-way ANOVA (for microhardness), followed by Tukey’s post hoc test (α=0.05). Results: The C group exhibited higher microhardness than the BF-F and BF-O groups, regardless of the solution used. A reduction in microhardness was observed in all groups when comparing initial and final time points. SEM images revealed variations in the size, amount, and arrangement of particles among the different resin composites. Conclusion: The study concluded that the microhardness of different bulk fill resin composites decreases when exposed to either the hydroelectrolytic beverage or distilled water. However, the type of immersion liquid did not influence the surface roughness of the evaluated composite resins.
Strong and tough polyvinyl alcohol hydrogels with high intrinsic thermal conductivity
Authors: Zhang Junliang , Tang Chenyang , Kong Qingqing , He Mukun , Lv Peng , Guo Hua , Guo Yongqiang , Shi Xuetao , Gu Junwei
Published: January 2025

Although polyvinyl alcohol (PVA) hydrogels display huge potential in tissue engineering, flexible and wearable electronic devices and soft robotics, their low intrinsic thermal conductivity and weak mechanical properties severely limit their wider applications in these areas. Herein, a Hofmeister effect-assisted “directional freezing-stretching” tactic is employed for simultaneously enhancing the intrinsic thermal conduction and mechanical properties of PVA hydrogels. The hydrogels are obtained through directional freezing followed by salting-out treatment and subsequent mechanical stretching and salting-out (DFS). The DFS PVA hydrogel with 15 wt% of PVA and a stretching ratio of 4 (DFS4) exhibits the highest thermal conductivity of 1.25 W/(m·K), which is 2.4 and 2.8 times that of PVA hydrogel prepared through frozen-thawed (FT) [0.52 W/(m·K)] and frozen-salted out (FS) [0.45 W/(m·K)] methods, respectively. The DFS4 PVA hydrogel also possesses greatly improved mechanical performances, exhibiting an elongation at break of 163.1%. In addition, the tensile strength, toughness, and elastic modulus of DFS4 PVA hydrogel significantly increase to 27.1 MPa, 25.3 MJ·m-3, and 21.5 MPa from 0.4 MPa, 0.32 MJ·m-3, and 0.07 MPa for FT PVA hydrogels, respectively. It is elucidated that the salting-out effect generates hydrophobic and crystalline regions, while directional freezing and stretching enhance the chain orientation in the DFS strategy. These effects synergistically contribute to the improvement of thermal conductivity and mechanical properties of PVA hydrogels.
Clinical and epidemiological aspects of multiple pregnancy
Authors:   Kazakhstan Medical University “Higher School of Public Health”, Almaty, Republic of Kazakhstan, Serikkyzy L. , Issenova S.Sh. ,   Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan, Nurbakyt A.N. ,   Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan, Lee A.A. ,   Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan, Sembayeva B.Zh. ,   Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan
Published: January 2025

Over the past few decades, the rate of multiple pregnancy has risen. This is due to the widespread use of assisted reproductive technologies (ART), as well as the increasing maternal age at pregnancy planning and the extensive use of oral contraceptives, after the withdrawal of which spontaneous maturation of two or more follicles can occur. Multiple pregnancy is associated with a higher risk of perinatal and maternal mortality and morbidity compared to singleton pregnancy, which may also have psychosocial and socioeconomic consequences for women and their families. Unlike dichorionic twin pregnancy, monochorionic twin pregnancy has specific complications due to shared maternal and fetal vascular connections. Based on this, updated strategies for the management of pregnancy and labor in women with multiple pregnancy are being developed to improve perinatal outcomes and correct specific complications of multiple pregnancy.
Objective. To conduct a literature review on current approaches to the management of multiple pregnancy to optimize medical care for pregnant women with multiple pregnancy.
Materials and methods. Literature data published between 2018 and 2023 in Medline, Scopus, Web of Science, PubMed, Willey, and Cochrane Library databases were analyzed. The search was performed using the following key words: multiple pregnancy, in vitro fertilization, twins, monochorionic twin pregnancy, selective reduction.
Results. Multiple pregnancy is associated with a higher risk of maternal complications, preterm birth and disability. The risks of multiple pregnancy for both mother and fetus should be discussed based on the individualized and balanced medical approach, including the options of conservative treatment or reduction of one or more fetuses, and the risks and benefits of both choices. The techniques used to correct specific complications of multiple pregnancy depend on chorionicity, skill level, and equipment availability in the clinical setting.
Conclusion. Different strategies and recommendations for the management of multiple pregnancy can optimize pregnancy outcomes. Further research may help to determine optimal recommendations for the management of multiple pregnancy, as well as identify additional factors that may influence pregnancy outcomes.
Key words: multiple pregnancy, in vitro fertilization (IVF), twins, monochorionic twin pregnancy, selective reduction
Beyond the womb: a study on psychomotor skills and neuropathology in children born after assisted reproductive technologies
Authors:   Kazakhstan Medical University “KSPH”, Almaty, Republic of Kazakhstan, Ilmuratova S.Kh. , Lokshin V.N. ,   International Clinical Center for Reproductive Medicine “PERSONA”, Almaty, Republic of Kazakhstan, Manzhuova L.N. ,   Scientific Center of Pediatrics and Pediatric Surgery, Almaty, Republic of Kazakhstan, Nurgaliyeva Zh.Zh. ,   Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan, Kussainova F.A. ,   Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan, Bazarbayeva А.A. ,   Scientific Center of Pediatrics and Pediatric Surgery, Almaty, Republic of Kazakhstan, Nekhorosheva V.A. ,   Institute of Reproductive Medicine, Almaty, Republic of Kazakhstan, Abshekenova A.T. ,   International Clinical Center for Reproductive Medicine “PERSONA”, Almaty, Republic of Kazakhstan
Published: January 2025

Objective. To determine the indicators of psychomotor development and the frequency of nervous system diseases in children born after assisted reproductive technologies (ART).
Patients and methods. A case-control study included 120 children born after ART and 132 naturally conceived children under 5 years of age. Inclusion criteria: a successful ART program between 2018 and 2023. Exclusion criteria: programs with donor oocytes/sperm, intrauterine insemination, and surrogacy. Medical history was collected in both groups, and examinations were performed, followed by statistical data analysis using IBM SPSS Statistics 26.
Results. Сhildren conceived via ART began to walk with support statistically significantly earlier than naturally conceived children. However, the frequency of immaturity of brain structures detected by neurosonography was statistically significantly higher. The analysis revealed a correlation with other perinatal factors. When constructing a logistic regression with forced inclusion of ART in the regression model with significant risk factors, the use of ART itself lost its significance, which also confirms the absence of an independent effect of ART on the development of immaturity of brain structures.
Conclusion. The use of ART does not negatively affect the neurological development of children. It is important to identify risk factors associated with infertility for timely intervention and rehabilitation of children at risk of developing cognitive diseases.
Key words: assisted reproductive technologies, cerebral palsy, cognitive health, immaturity of brain structures, psychomotor development, offspring, autism spectrum disorder, attention deficit hyperactivity disorder
Integration Life Skills Education In History Learning With Online Learning On The Covid-19 Pandemic (Case Study in SMA N 1 Boyolali)
Authors: Assidiqi Muadz , Sariyatun Sariyatun , Purwanta Hieronymus
Published: January 2025

Anderson and Krathwohl's overly rigid use of educational taxonomy led to life skills education having no clear fundamentals. This research aims to illustrate the integration of life skills in soft skills in historical learning during the Covid-19 pandemic at SMAN 1 Boyolali High School with a taxonomy of life skills education. This research is descriptive qualitative research with a case study approach. The data source in this study is obtained through interviews, observations, and documentation narrated into a sentence. Furthermore, the data source is analyzed interactively through data condensation, presentation, and conclusions. The results of this study are a detailed depiction of indicators of life skills education integrated by history teachers to improve students' soft skills. The newness in this study is the use of taxonomy of life skills education that is still not widely known by teachers and educational academics.
Attitudes of Poverty Aid Recipients in Kelurahan Melayu Kota Piring
Authors: Rahmawati Nanik , Solina Emmy , Elsera Marisa , Wahyuni Sri , Anggriawan Dedi
Published: January 2025

This study aims to analyze the attitude of the community in terms of receiving poverty assistance. This research was conducted because it was found in the community that the number of people who were helped by looking at the integrated basic data (BDT) did not decrease even though the assistance provided was numerous and varied. UDB is used as a basis for disbursing government assistance to reduce poverty. Including, the poverty rate shows that there is no significant reduction in the poverty rate, and even tends to remain unchanged. The names of the same beneficiaries always appear from year to year. This study aims to determine how the attitude of the community in receiving the assistance. Using qualitative methods, it is used to analyze the attitudes of recipients of poverty assistance. some people still survive as recipients of poverty assistance, even though they are economically capable, and continue to remain in active status in the government database.