bluuebunny/crossref_metadata_2025 huggingface dataset:
A review on analytical method development and validation of Erlotinib
Authors: Nuli Mohana Vamsi
Published: May 2023

In this review article determines the different analytical methods for the quantitative establishment of Erlotinib by using HPLC, HPLCMS, HPLC-UV, LC-MS/MS. Pharmaceutical analytical method development of Erlotinib requires valid analytical procedures for quantitative and qualitative analysis in Pharmaceuticals dosage formulations and human serum. This assessment explains that the superiority of the HPLC/LC-MS methods reviewed is based on the quantitative analysis of drugs in formulations, (API), biological fluids such as serum and plasma.
Improving Mental Health in Older Adults
Authors: Lee Virginia
Published: May 2023

There are significant mental health disparities in older people in underserved communities and disadvantaged racial and ethnic groups. Blacks are less inclined to have a mental diagnosis or receive mental health treatments [1]. Older Asian American women have higher rates of suicidal ideations and completions than women from other ethnic and racial groups. Blacks’ and Hispanics’ incidence of the disease is higher (2x and 1.5x respectively), but receiving a diagnosis is much lower [1]. There is a correlation between mental health conditions and cognitive impairment. Contributor factors are stress, disparities that put them at risk for cognitive impairments, ageism increased other forms of discrimination and mental health issues [1].
Comparison of Resuspension Techniques on the Cellular and Cytokine Characteristics of Platelet Rich Plasma: A Pilot Study
Authors: Kutcher Josh
Published: May 2023

Background: Platelet Rich Plasma (PRP) is increasingly used for a variety of musculoskeletal ailments such as tendinopathy and arthritis. There are numerous protocols for preparing PRP, but to our knowledge there have been no studies to assess the impact that re-suspension techniques may have on the cellular characteristics and growth factor expression of the final PRP product. Hypothesis: The type of re-suspension technique used will alter the platelet characteristics and growth factor expression of PRP.

Study Design: Descriptive laboratory study. Methods: Blood was collected from nine healthy volunteer donors between ages 26-60. Informed consent and ethics approval was obtained. A double spin technique was used resulting in a concentrated PRP product. Three commonly employed re-suspension techniques were utilized to re-suspend the final PRP product and the cellular characteristics and growth factor expression were analyzed using a reproducible protocol. This study was completed over a single day.

Results: All three re-suspension techniques resulted in a 4.6-5.2-fold increase in platelet concentration with no difference between groups (p=0.31). This is consistent with the recommended PRP concentration in published literature. Each re-suspension technique also demonstrated in increase in concentration of PDGF and VEGF with no difference between groups (p=0.81 and p=0.97).

Conclusion: This pilot study suggests that the re-suspension techniques may be equivalent and do not result in altered cellular or growth factor characteristics within the study limitations. Clinical Relevance: The mixing method can be labor and time intensive and prolong patient wait times. The vortex method can shorten the overall patient encounter time while still providing an optimal PRP product. Previously, there were only theoretical assumptions regarding how the re-suspension techniques may modify PRP characteristics.
Modelación de barreras energéticas para la transición industrial en la Economía Circular
Authors: Lámbarry-Vilchis Fernando , Moreno-Jiménez Juan Carlos
Published: May 2023

Los sistemas industriales de producción mientras agotan las existencias de materiales, liberan emisiones en formas que la naturaleza no puede asimilar, para solventar esta situación una incipiente alternativa es transitar a un modelo de Economía Circular en el que los procesos industriales optimicen sus flujos energéticos y se sustituya la demanda y participación de energías fósiles por renovables, situación que ha presentado barreras que aún no se entienden del todo y que han obstaculizado su adopción. Es por ello que, el objetivo de esta investigación consistió en modelar las barreras energéticas, a través del Modelado Estructural Interpretativo y la Matriz de Impacto Cruzado-Multiplicación Aplicada a la Clasificación. Se concluye que las barreras y sus interrelaciones prioritarias se orienten a lo político-regulatorio, por lo que se sugiere promover un marco jurídico fundamentado en las mejores prácticas internacionales para fomentar la transición a la circularidad energética.
Administrative and Legal Aspects Related to CombatGambling and Computer Addiction in Young People
Authors: Omelchenko Andrii , Serdiukov Olexii , Moshkovskyi Andrii , Symon Yuriy , Andrushchenko Igor
Published: May 2023

The objective of the study is to determine the forms, types and factors of computer addiction and gambling in young people, as well as propose ways to counteract their negative impact. The methodological basis of the study is sociological research, analysis of state policy and regulations; methods of classification and generalization. Results: the authors have proven that Government policy should be aimed to improve the information culture of users of the global network, the formation of skills for safe work in cyberspace and mastering the rules and norms of behaviour in cyber reality. The main ways to counteract the negative impact of computer addiction on young people are suggested, in particular, encouraging public organizations to identify people addicted to gambling and provide them with information on rehabilitation centers and forms of rehabilitation; limiting the time minors spend in play areas; establish information security standards in the activities of the organizers of games for money, and promote the principles of responsible gambling.
Digital Healthcare in the Context of Challenges and Opportunities of Technological Progress in the Countries of the European Union
Authors: Nikitenko Vitalina , Voronkova Valentyna , Kozar Yurii , Oleksenko Roman , Yanchevskyi Oleksandr , Korobko Igor
Published: May 2023

The objective of the article is to investigate the theoretical and practical aspects of digital medical care in the context of the challenges and opportunities of technological progress, and to outline the main guidelines for the development of digital technologies in the field of Medicine. The methodology consists in the use of a systematic method, which offers the achievement of sustainable development of digital technologies of medical institutions; the proposal is based on the adaptability and flexibility of the management structures of medical institutions, capable of using the available data and digital technologies to provide assistance to the population; a synergistic method based on self-organization and the search for the bases of self-organization, which can help medical institutions to overcome the crisis and instability. The study shows that the digital change is increasingly visible in Medicine. Thanks to digital technologies and tools in Medicine, particularly through eHealth technologies, prevention, diagnosis, treatment, monitoring and administration have been improved. The problems of digitization are discussed not for themselves, but for the improvement of medical care, digital health in the context of the challenges and opportunities of technological progress, the formation of a new concept of digital technologies in the field of health. KEYWORDS: Digital technologies, medical field, digital healthcare, artificial intelligence, data management, innovations
Staphylococcus aureus resistente a meticilina (SARM) en fosas nasales y teléfonos celulares en estudiantes y trabajadores del área de la salud: Revisión sistemática
Authors: Zuta Arriola Noemi , Rojas Salazar Arcelia Olga , Zela Pacheco Laura Margarita , Salazar Salvatierra María Elena , Siccha Macassi Ana Lucy
Published: May 2023

El objetivo del presente estudio fue sintetizar el conocimiento existente referente a la presencia de Staphylococcus aureus resistente a meticilina en teléfonos celulares y en las fosas nasales de estudiantes y trabajadores del sector salud. El método que se empleó fue de enfoque cualitativo, utilizando la revisión sistemática de un total de 496 artículos, de los cuales se seleccionaron 22. Los resultados indican que existe una colonización nasal de Staphylococcus aureus resistente a meticilina en una proporción que oscila desde el 1.2% y el 11.1%. Se concluyó que este patógeno está presente en las fosas nasales mediante la infección directa durante el uso de teléfonos celulares en el entorno hospitalario y por la evidente falta de medidas de higiene y bioseguridad.
The Use of Digital Marketing Technologies in the Commercial Activity to Increase Enterprises’ Value in the COVID-19 Conditions
Authors: Kovalchuk Svitlana , Arefieva Olena , Shevchenko Anna , Kononov Oleksandr , Subachov Mykola
Published: May 2023

Under the current conditions of the COVID-19 pandemic, the practice of providing goods and services, as well as their availability to consumers, remains relevant and requires further scientific research. The purpose of the article is to substantiate the conceptual basis of using digital marketing technologies in the commercial activities of enterprises to increase their value, competitiveness and ensure sustainability of development in the conditions of the COVID-19 pandemic. The methodological basis of the study of the use of digital marketing technologies in the commercial activities of enterprises in the conditions of the COVID-19 pandemic is a systematic approach and principles of digital marketing management, including: goal orientation, efficiency, functionality and complexity. The feasibility of the complex application of digital marketing tools in the commercial activities of the enterprise for the implementation of the marketing strategy in the conditions of the COVID-19 pandemic has been proven, including: contextual advertising, SEO and SEM promotion, banner advertising, advertising windows, television advertising, radio advertising, advertising in gaming, shopping and other applications, native advertising, SMS mailing, QR codes in offline mode, viral advertising, advertising in messengers, teaser advertising, retargeting. The advantages and disadvantages of using digital marketing in the commercial activity of the enterprise in the conditions of the COVID-19 pandemic are highlighted. The need to apply promising innovative implementations in the field of digital marketing has been proven, which should include: the use of online testing; implementation of voice search; use of chat bots; use of video marketing; use of interactive content.
STRATEGI KOMUNIKASI LURAH DALAM MENSOSIALISASIKAN VAKSINASI COVID-19 PADA MASYARAKAT DI KELURAHAN MANGGA SIMALINGKAR
Authors: Sianturi Gabrela Afriyanti , Pinem Shabrina Harumi , Aruan Rita Vinolia
Published: May 2023

Sejak kasus pertama Coid-19 diumumkan pada tanggal 2 maret 2020, jumlah kasus penyebaran covid-29 semakin meningkat dan sangat mudah menyebar, kelompok lansia sering di dominasi dengan kelompok yang rentan mudah terkena karena kondisi fisiologisnya dan sistem imun tubuh yang menurun dan rendah. Dalam hal itu pemerintah Indonesia terutama kelurahan Mangga Kecamatan Simalingkar melakukan tindakan pembatasan sosial, penyekatan pembatasan, penyemprotan disfektan  dan pemberian edukasi terhadap bahaya dari penularan covid-19 serta menggunakan masker. Tujuan dari penelitian ini untuk mengetahui strategi komunikasi dan hambatan lurah dalam mensosialisasikan vaksinasi covid 19 kepada masyarakat di kelurahan mangga kecamatan medan tuntungan. Dari penelitian mendapatkan hasil yang menunjukan kalau strategi komunikasi lurah didalam mensosialisasikan vaksinasi covid-19 adalah dengan lurah sebagai komunikator dan masyarakat sebagai komunikan, dengan isi pesan atau informasi mengenai penyuluhan dan penjelasan tentang vaksin yang disampaikan melaui secara langsung dan menggunakan media online (wa) dan media cetak (spanduk) dengan harapan agar masyarakat mau untuk divaksin sehingga menurunkan penyebaran covid-19. Tetapi ditemukan beberapa kendala seperti kesimpangsiuran informasi tentang vaksin yang membuat masyarakat takut akibat gejalanya setelah divaksinasi.
Kırgızistan'da Üniversitelerin Instagram Kullanımı Üzerine Bir Araştırma
Authors: ŞARŞENKADIROVA Acar , MAKSÜDÜNOV Azamat
Published: May 2023

Bilgi ve iletişim teknolojilerinin kurum ve kuruluşlar tarafından benimsenmesi hızla sürerken, durumun ülkelere göre, sektörlere göre farklılık göstermesi de bilinen bir gerçektir. Bu çalışmada Kırgızistan’da faaliyet göstermekte olan özel ve devlet üniversitelerinin Instagram kullanım durumları değerlendirilmektedir. Çalışmada öncelikle Instagram’ı aktif olarak kullanmakta olan üniversiteler belirlenmiş ve onların paylaşımları içerik analizine tabii tutulmuştur. İçerik analizi takipçi sayısı, paylaşımların formatı, dile göre dağılımı, takipçilerin tepkisi gibi kriterlere göre yapılmış ve karşılaştırmalı olarak analiz edilmiştir.Araştırma sonuçlarına göre, Kırgızistan’da üniversitelerin %43,3’ünün Instagram’a kayıtlı oldukları ve çok az bir kısmının aktif olarak kullandıkları tespit edilmiştir. Çalışmanın sonuçları Kırgızistan’daki üniversitelerin sosyal medya pazarlaması konusundaki genel durumunu görmeleri ve daha etkili olabilmeleri için gerekli olan ipuçlarını sağlaması açısından önemlidir.
CONCENTRATED SOLAR THERMAL TECHNOLOGY FOR POWER GENERATION AND ITS CASE STUDIES
Authors:   B. Tech, Department of Mechanical Engineering,Delhi Technological University,Delhi -110042, India, Singh Dipanshu , Chauhan Dipanshu ,   B. Tech, Department of Mechanical Engineering,Delhi Technological University,Delhi -110042, India, Verma Dev Kumar ,   B. Tech, Department of Mechanical Engineering,Delhi Technological University,Delhi -110042, India, Kesari J.P. ,   Adjunct Faculty, Department of Mechanical Engineering, Delhi Technological University, Delhi-110042, India
Published: May 2023

The dependence on conventional energy sources since the Industrial revolution has increased extensively, affecting our environment. Over-exploitation of natural resources has led to the increased global average temperature rise of approximately 2°C per year and the emission of toxic gases and byproducts that can cause health complications. Further, it can cause acid deposition due to the reaction between Nitrogen oxides and Sulphur dioxide mixing with water, Oxygen, and other chemicals in the air which affects architecture, crops, marine, and wildlife. Hence, there is an urgent need to transition from conventional sources like fossil fuels to renewable energy. Solar energy is of two types: Solar Photovoltaic (PV) where Photovoltaic cells (panels of semiconductor cells) are used to collect both direct and scattered rays and convert them into electricity and Solar Thermal Energy where the sun’s heat is captured. So our area of research involves CST technology and a detailed analysis and case study of India One Solar Thermal Power Plant located in Abu Road, Rajasthan, and PS10 located in Seville, Spain, and check its economic feasibility. There are benefits and drawbacks to CST technology. Even though India One and PS10 are noteworthy accomplishments in the field of renewable energy, there are still several issues with the technology that need to be resolved in order to make it a more viable and affordable choice.
Elaboration of the Analysis Method of Ketamine Isolated from Biological Fluids Using Ultraviolet Spectrophotometry
Authors:   Doctor of Medical Sciences, Tashkent Pharmaceutical Institute, Rizaev Kamal Saidakbarovich
Published: May 2023

The article is devoted to the results of studies on the development of thin–layer chromatography (TLC) and UV–spectrophotometry analysis methods and introduction of ketamine to the determination of the substance extracted from the composition of biological fluids. The methods developed during the research were applied to the analysis of ketamine extracted from biological fluids and positive results were obtained.
Perception of Knowledge and Level of Preparedness towards Cardio Pulmonary Resuscitation (CPR) Among Physicians in a Tertiary Care Centre of Eastern India
Authors:   Consultant (EM&ICU), Kolkata heart lung centre, India, J. Mahato
Published: May 2023

Cardiopulmonary resuscitation is the main stay of treatment to revive patient who are in cardiac arrest and traditionally it was conducted under the supervision of emergency, critical care and anesthesia department. Knowledge of CPR and preparedness towards CPR among other specialty remains questionable. It has been observed through there are ample of data from developed countries but there is a paucity of work in developing countries regarding the same. OBJECTIVE: To assess the knowledge and level of preparedness and to assess the perception towards cardiopulmonary resuscitation among physicians and to determine factors influencing the same and the recommendation for further improvement. METHODOLOGY: This cross-sectional questionnaire-based study was conducted using a sample of 41 physicians employed in different specialties of Medica super specialty hospital using a pre validated questionnaire for a period of 12 months. Fischer exact test or Chi Kolmogorove -Smirnov analysis has been used to check if data is following the normal distribution. Pearson’s correlation analysis or Spearman’s rank correlation analysis has been used to assess correlation between two variables. RESULT : 41 physicians responded among 80 contacted (n=41,response rate= 51.25%).In our study The mean age of the participants was 39.46 (±9.01) years with a median of 38 years. The age ranged from 2564 years. 75.6% of the respondents were males. Major group of participants are belonged to emergency medicine (29.3% ) followed by non-interventional cardiology.43.9% of study populations are holding doctor level medical degree.39% of study population is holding ACLS /BLS certification. 100% of physician of study population are being aware of importance of CPR and 73.2% are keen to take part in CPR awareness programme. Most of the physicians (75.6%) believe teaching and mastering CPR intervention should be made mandatory to all medical undergraduates. There was no significant association of specialty, highest qualification, years of experience or presence of ATLS certification with score on question regarding main purpose of CPR. There was a significant association of score on this question with presence of ACLS/BLS Certification, with all respondents who possessed ACLS/BLS certification answering all options correctly. CONCLUSION :The study showed variable level of perception of knowledge and level of preparedness towards cardiopulmonary resuscitation among physicians and there are no single variable or determined factor for above. Though the study indicates there is correlation between the ACLS/BLS/ALS certification and knowledge of CPR further study and evaluation is needed in context of developing countries. It is also recommended a refresher course intending towards last years of medical school would be beneficial regarding knowledge of CPR
Holmium Laser Enucleation of the Prostate (HOLEP) Technique: A Safe and Effective Option in Transurethral Prostate Resection
Authors:   1Hospital General de Zona 194 Instituto Mexicano del Seguro Social. Naucalpan de Juárez, México, Rivera Cabañas José Guadalupe , Fernando García Padilla ,   Facultad de Medicina de la Universidad Nacional Autónoma de México, Ciudad Universitaria. México, México., Islas Gabriela Cruz ,   Hospital General “Dr. Gaudencio González Garza” del Instituto Mexicano del Seguro Social, Ciudad de México, México., campa Rafael Valdivia ,   Hospital general de Especialidades del Estado de Sonora, Secretaría de Salud. Hermosillo, Sonora, México
Published: May 2023

Holmium laser enucleation of the prostate (HOLEP) is a surgical technique increasingly used in transurethral resection of the prostate. This procedure has been shown to be safe and effective in the treatment of benign prostatic hyperplasia, offering a higher success rate in the removal of prostate tissue and a lower rate of complications compared to other methods of transurethral prostate resection. In addition, HOLEP has been used successfully in patients with large prostates and those with coagulation disorders, making it a safe and effective treatment option for a wide variety of patients. In summary, HOLEP is an effective and safe surgical technique in transurethral resection of the prostate, and may be an attractive treatment option for patients seeking a rapid recovery and reduced complication rate.
New ICU Design and Patient Outcome
Authors:   Engineer department, Dawssari Mobarak Al , Motlaq Khalid Al ,   Engineer department, Mokni Narjes Salem ,   Internal medicine department ( neurology), Fathi Neveen ,   CQI & PS Department, Dawssari Hassen Al ,   Surgery department
Published: May 2023

Hospital length of stay (LOS) is a quality metric health systems use as a proxy of efficient hospital management (1). Many strategies to reduce ICU length of stay (LOS) have been implemented, but few studies have evaluated the role of ICU design in reduction of LOS and outcome. This study was informed by the need to compare ICU performance in terms of length of stay and outcome before the upgrade of the ICU facilities and organizational structure (January 2018 – December 2019) and after upgrade of the ICU facilities (January 2020 – December 2021). Finally we demonstrate the impact of ICU design in reducing costs of ICU patients.
Peran Korban Pemerkosaan Dalam Membantu Proses Penyidikan
Authors: Tanasale Christy , Toule Elsa Rina Maya , Sopacua Margie Gladies
Published: May 2023

Introduction: Rape is one of the most common crimes in society.Purposes of the Research: The purpose of this study is to analyze and discuss the role of the victim in revealing the perpetrators of the crime of rape in the investigation stage and legal protection for victims of rape in the investigation process. Methods of the Research: In this legal research, the author uses normative juridical legal research which obtains data from literature studies in the form of laws, documents, books, magazines and other literature related to writing.Results of the Research: The results of this study indicate that the role of rape victims in the investigation stage is when the victim dares to report, the victim is open and the victim is cooperative and the victim includes clear information, because the role of the victim is very influential in the investigation process. For this reason, there is legal protection for rape victims, where victims get legal protection which is quite clearly stated in Law Number 31 of 2014. As well as other protections such as Juridical Protection, Psychological Protection and Social Protection. So, the authorities can take protective measures for victims and sanctions for perpetrators in accordance with the provisions of applicable regulations.
Penerapan Kelangsungan Usaha Bagi Debitor Pailit Dalam Penyelesaian Perkara Kepailitan Dan Penundaan Kewajiban Pembayaran Utang
Authors: Simaremare Erwin , Tjoanda Merry , Saija Ronald
Published: May 2023

Introduction: The application of the principle of business continuity is very difficult for debtors to apply.Purposes of the Research: The purpose of this research is to examine and find out what are the factors that can affect the implementation of going concern for debtors in bankruptcy and postponement of debt payment obligations and the application of going concern as an effort to fulfill the obligations of bankrupt debtors to creditors in bankruptcy matters. Methods of the Research: The method used in this research is normative juridical research method, analytical descriptive research type, sources of legal materials are primary legal materials, secondary legal materials and tertiary legal materials. Analysis of legal materials and methods of analysis of legal materials.Results of the Research: The results of this research and discussion show that: (1) In the application for bankruptcy and PKPU should not only look at the requirements as in Article 2 paragraph (1) and through simple evidence, but also the importance of an insolvency test to determine the extent of the debtor's ability to carry out his obligations, so that The business continuity of the debtor is also protected from being declared bankrupt immediately. (2.) With the continuation of coal mining operations, the bankrupt debtor PT. Rinjani Kertanegara with the aim of increasing bankruptcy assets, it is likely that the rights of creditors on their receivables will be fulfilled.
Formulação fúngica com o fungo nematófago Pochonia chlamydosporia no controle biológico das nematodioses de bovinos em Viçosa-MG-Brasil
Authors:   , Fonseca Júlia dos Santos
Published: May 2023

No controle de vermes bovinos, destaca-se o controle biológico por fungos nematófagos, principalmente Pochonia chlamydosporia que causa a destruição de ovos de helmintos. Este estudo teve como objetivo testar a eficácia de uma formulação contendo o fungo nematófago Pochonia chlamydosporia para o controle biológico da nematodiose bovina. Doze bovinos foram divididos em dois grupos: grupo controle (GC) e grupo que recebeu a formulação (GT). Durante seis meses, no GT cada animal recebeu 1g (10 5 chlamidósporos) de Pochonia chlamydosporia para cada 10 kg de peso vivo animal, administrado diariamente conjuntamente com ração comercial. Já no GC cada animal recebeu a mesma dosagem, porém, do placebo (farelo de arroz), sem o fungo adicionado a ração. Amostras de fezes e pastagens foram coletadas para a pesquisa de nematoides gastrointestinais. Vermes pulmonares e trematódeos foram investigados. Os animais foram pesados mensalmente. As médias de temperatura e precipitação foram registradas. A oferta do fungo Pochonia chlamydosporia não foi eficaz na redução dos ovos por grama de fezes de nematóides gastrointestinais (OPG) dos animais, não diferindo estatisticamente (p>0,05) entre os grupos. Os valores médios de larvas recuperadas no pasto não diferiram significativamente (p>0,05). O gênero Haemonchus sp. foi o mais prevalente. Não houve correlação entre o número de larvas com temperatura e precipitação (p>0,05). Houve diferença estatisticamente significativa (p<0,05) na penúltima pesagem do experimento. A formulação contendo Pochonia chlamydosporia não foi eficiente no controle biológico de nematóides gastrointestinais bovinos. Palavras-chave: Biocontroladores. Helmintos. Verminose.
Populações de Clostridium spp. em carne bovina embalada a vácuo associadas a blown pack
Authors:   , Freitas Caio Fialho de
Published: May 2023

A carne bovina é uma das variedades de carne mais consumidas no mundo e tem relevante importância para e economia. A embalagem a vácuo é comumente utilizada para estender a vida útil deste produto, impedindo a multiplicação de microrganismos aeróbios. No entanto, o ambiente de anaerobiose gerado permite a multiplicação de microrganismos anaeróbios, como Clostridium spp., que podem causar prejuízos consideráveis às indústrias de alimentos, como a deterioração blown pack. O objetivo do estudo foi associar a presença e contagens de Clostridium sulfito redutor e Clostridium perfringens em carne bovina embalada a vácuo com a deterioração blown pack, considerando diferentes temperaturas de conservação. Amostras de carne bovina embalada a vácuo (n = 10) foram armazenadas a 4 °C e 15 °C durante o período de 28 dias, com monitoramento semanal das contagens de Clostridium sulfito redutor e C. perfringens e verificação da presença da deterioração blown pack. A presença de clostrídios sulfito redutores e C. perfringens foi constatada em 70% das amostras. Dos isolados característicos obtidos, 100% foram confirmados como Clostridium sulfito redutores e 79,8% foram identificados como C. perfringens. A contagem máxima de Clostridium sulfito redutor a 4 °C e 15 °C foi de 0,39 log10 UFC/g e 2,03 log10 UFC/g, respectivamente. A contagem máxima de C. perfringens a 4 °C e 15 °C foi de 0,18 log10 UFC/g e 1,74 log10 UFC/g, respectivamente. Alternativamente, observamos o surgimento da deterioração blown pack em 90% das amostras armazenadas a 15 °C. Através dos resultados obtidos, podemos concluir que a temperatura de refrigeração a 4 °C controlou a multiplicação desses microrganismos quando comparado com a temperatura inadequada de armazenamento, a 15 °C, durante o período de 28 dias. Além disso, concluímos que a carne bovina embalada a vácuo, quando armazenada em temperatura inadequada de 15 °C, em um período aproximado de 7 a 21 dias, pode apresentar o surgimento da deterioração blown pack. Palavras-chave: Carne bovina. Clostridium spp. Clostridium perfringens. Blown pack.
ФАРҒОНА ВОДИЙСИДА БОШЛАНГАН ОЧАРЧИЛИКНИНГ САБАБЛАРИ ҲАМДА 1917-1918 ЙИЛЛАРДАГИ ИҚТИСОДИЙ АҲВОЛ
Authors: Бахридинов Қаҳрамон
Published: May 2023

Мазкур мақолада Фарғона водийсида 1917-1918 йиллардаги иқтисодий аҳволнинг ўзига хос хусусиятлари, водийда советлар тузумининг ўрнатилиши ва большевиклар иқтисодий сиёсатининг моҳияти, водий аҳолисини озиқ-овқат билан таъминлаш масаласининг кескинлашуви, бунда совет ҳокимияти вакилларининг йўл қўйган хатоликлари,Фарғона водийсида даҳшатли очарчиликнинг вужудга келиши ва унинг аянчли манзараси статистик тўпламлар, архив материаллари ва илмий адабиётлар асосида таҳлил этилган.
ОЛИЙ ТАЪЛИМ ИЛМИЙ МУҲИТИДА ИНСОН КАПИТАЛИНИ ФАОЛЛАШТИРИШ МАСАЛАСИ
Authors: Хажимуратов Абдуқаҳҳор
Published: May 2023

Мақолада инновацион тадбиркорликни ривожланишига асос бўлган интеллектуал капитални фаоллаштириш масалалари ўрганилган. Бунга кўра, Ўзбекистондаги олий таълим муассасаларида эркин бозор механизмларини шаклланиши жараёнида, инновация фирмаларини ташкил этиш ва пировард илмий маҳсулот яратишда бугунги кунда учрайдиган қатор муаммолар аниқланиб, уларнинг ечимлари кўрсатилган.
INGLIZ VA OʻZBEK TILLARIDAGI ADJEKTIV KOMPONENTLI KOMPARATIV FRАZEOLOGIK BIRLIKLАRNING QIYOSIY TAHLILI
Authors: Xolmatova Malika
Published: May 2023

Ushbu maqola adjektiv komponentli komparativ frazeologizmlarni turli tillar doirasida qiyosiy oʻrganib, ularning til va nutq bosqichlaridagi umumiylik va xususiylik dialektikasini yoritishga bagʻishlangan. Iboralarni har ikkala til doirasida oʻrganish, ularning lingvomadaniy, semantik-grammatik va funksional stilistik xususiyatlarini ochib berish mazkur ishning dolzarbligini belgilaydi.
ФУТБОЛЧИЛАРНИНГ ТЕХНИК-ТАКТИК ҲАРАКАТЛАРИ САМАРАДОРЛИГИНИНГ ЖИСМОНИЙ ТАЙЁРЛАНГАНЛИК ДАРАЖАСИ БИЛАН БОҒЛИҚЛИГИ
Authors: Мельзиддинов Руслан
Published: May 2023

Мазкур мақолада ёш футболчиларнинг техник-тактик ва жисмонан ривожлантириш бўйича спорт соҳасидаги маҳаллий ва хорижий олимларнинг илмий ва амалий тажрибалари, илмий адабиёт манбааларида келтирилган илмий-назарий маълумотлар ўрганилган. Ёш футболчиларнинг машғулот жараёнини таҳлил қилиш орқали уларнинг техник-тактик ҳамда жисмоний тайёргарлигини ривожлантиришнинг замонавий усуллари тадқиқот жараёнида қўлланилган. Тайёргарлик даражасини назорат қилиш юзасидан илмий-назарий фикрлар илгари сурилган ҳамда илмий тадқиқот ишлари олиб борилган, тадқиқотдан олинган натижалар қиёсий таҳлил қилиниб, тегишли хулосалар чиқарилган.
Population identity of humpback whales (Megaptera novaeangliae) in the waters of the US mid-Atlantic states
Authors: Barco Susan G. , McLellan William A. , Allen Judith M. , Asmutis-Silvia Regina A. , Mallon-Day Richard , Meagher Erin M. , Pabst D. Ann , Robbins Jooke , Seton Rosemary E. , Swingle W. Mark , Weinrich Mason T. , Clapham Phillip J.
Published: May 2023

In recent years, humpback whales (Megaptera novaeangliae) have been observed in the waters of the US mid-Atlantic states (USMA; New Jersey to North Carolina), notably in winter. The level of the mortality in this area (52 recorded deaths from 1990-2000), makes it important to understand the nature and population identity of this aggregation. Of the approximately 100 humpback whales documented in this study, photographs of 41 (live or dead) were of sufficient quality to be compared to catalogues from the Gulf of Maine (GOM, the closest feeding ground) and elsewhere in the North Atlantic. Of 22 live whales, 10 (45.5%) matched to the GOM, 5 (22.7%) to Newfoundland and 1 (4.5%) to the Gulf of St Lawrence (GSL). Of 19 dead whales, 6 (31.6%) were known GOM whales. Although the population composition of the USMA is dominated by GOM whales, lack of recent photographic effort in Newfoundland makes it likely that the observed match rates under represent the true presence of Canadian whales in the region. Length data from 48 stranded whales (18 females, 22 males and 8 of unknown sex) suggest that 39 (81.2%) were first-year animals, 7 (14.6%) were immature and 2 (4.2%) were adults. However, sighting histories of five of the dead whales indicate that some were small for their age and histories of live whales further indicate that the population contains a greater percentage of mature animals than is suggested by the stranded sample. The authors suggest that the study area primarily represents a supplemental winter feeding ground that is used by humpbacks for more than one purpose. From a management perspective, although the only successful matches of mortalities to date have been to the GOM, the observed mixing of live whales from different summer stocks might suggest that the high numbers of mortalities occurring there may not be impacting this single stock alone. Although further data are required before conclusions can be drawn, the mortality rate may be significant for the GOM population and this warrants further investigation.
Errors in age estimates of North Atlantic minke whales when counting growth zones in bulla tympanica
Authors: Olsen Erik
Published: May 2023

Age estimation of common minke whales (Balaenoptera acutorostrata) has always been difficult, and the accuracy of the current method of counting growth layer groups (GLGs) in the periosteal zone of the tympanic bulla has been questioned. To evaluate this method, two readers aged three sections from each of right and left bulla tympanica from 35 male and 57 female North Atlantic minke whales. A single age estimate with variance was calculated for each whale using General Linear Mixed Model Poisson based regression, and this estimate was compared with the number of ovulations and body length to evaluate the bias of the age determination method. The results showed a poor fit between age and number of ovulations with R2 = 0.0014. Bias was estimated to be a 37% underestimate of ‘true’ age assuming an ovulation rate of one per year and age at sexual maturity of eight years. Precision of the bulla age estimates was lower than those of Antarctic minke whales aged using the earplug method. The high bias reduces the applicability of the bulla method in routine age-determination with a management objective. Other age determination methods for the species should be improved or developed to ensure proper monitoring of demography and life history for the North Atlantic minke whale.
Frequency of Depression, Anxiety and Stress in Health Care Workers Serving in COVID-19 Wards
Authors: Ur Rahman Dr.Aitmad , Ejaz Dr.Usman , Dr.Ahtasm Dr.Ahtasm , Zartasha Dr.Amina , Zafar Dr.Saman , Asif Dr.Namra
Published: May 2023

Purpose: The COVID-19 pandemic has affected the lifestyles of millions of individuals worldwide and is likely to cause psychological health issues in those who work in Covid-19 wards. To find out the Frequency of depression, anxiety and stress in health care workers serving in Covid-19 wards.  

Methodology: In this cross-sectional study, data were gathered from various hospitals in Lahore and 280 participants were recruited using a non-probability convenient sampling technique. The study included both male and female health care professionals, in particular doctors, nurses, and paramedics, working in Covid wards for at least one month in both the public and private sectors. Participants with experience of less than 1 month and lab workers were excluded from the study. Depression Anxiety and Stress scale was used to collect data. Data was collected by distributing questionnaires to the participants and analyzed their response by using SPSS version 21.0 statistical software.

Findings: The results showed that mean ±S.D of participants were 26.55±3.367. Among all participants 148 participants were female and 132 were males. Among 89 doctors 10 felt severe stress, 2 found moderate and 65 doctors were normal.136 Nurses participated in study and 15 felt severe stress, 53 found moderate stress working in COVID-19 wards. Among 55 paramedics, 7 participants felt severe stress, 13 found moderate stress working in COVID-19 wards. Among 89 doctor participants 17 found moderate depression, 77 nurses and 50 paramedics found moderate depression working in COVID-19 wards.

Recommendations: It was concluded from the study high levels of stress and burnout, and moderate depression were found in Nurses', then paramedics were affected and least stress, depression and anxiety were found in doctors.
PEMBUATAN MINUMAN FUNGSIONAL DARI DAUN BIDARA (Zizhipus mauritiana, Lam)
Authors: Dini Dini Novita Sari
Published: May 2023

Penelitian ini dilakukan di Laboratorium Farmasi, Fakultas Farmasi Universitas Sumatera Utara dari bulan April sampai dengan Juni 2022. Tujuan penelitian untuk mengetahui karakteristik fisik, kimia dan organoleptik minuman fungsional instan dari daun bidara (Ziziphus mauritiana, Lam) dan kayu manis. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 3 ulangan. Perlakuannya adalah pencampuran bubuk ekstrak daun bidara, bubuk ekstrak kayu manis dan Stevia masing-masing: A = (0,2 g bubuk ekstrak daun bidara + 0,2 g bubuk ekstrak kayu manis + 0,5 g Stevia), B = (0,4 g bubuk ekstrak daun bidara + 0,2 g bubuk ekstrak kayu manis + 0,5 g Stevia), C = (0,6 g bubuk ekstrak daun bidara + 0,2 g bubuk ekstrak kayu manis + 0,5 g Stevia), D = (0,8 g bubuk ekstrak daun bidara + 0,2 g bubuk ekstrak kayu manis + 0,5 g Stevia), E = (1,0 g bubuk ekstrak daun bidara + 0,2 g bubuk ekstrak kayu manis + 0,5 g Stevia). Berdasarkan hasil uji fisik, kimia dan organoleptik maka ditetapkan produk terbaik minuman fungsional instan adalah perlakuan A (Pencampuran bubuk ekstrak daun bidara 0,2 g + bubuk ekstrak kayu manis 0,2 g + Stevia 0,5 g) dengan karakteristik mutu antara lain: waktu larut 15,32 detik, kadar air (4,282%), kadar abu (1,276%), aktivitas antioksidan (4,07%), kadar klorofil (1,436%), angka lempeng total (2,1 × 10² koloni/g), uji sisa pelarut (0,7%), serta penerimaan panelis terhadap warna (3,89), rasa (3,81) dan aroma (4,19).
ANALISA KELAYAKAN USAHA BUDIDAYA TANAMAN PISANG KEPOK (Musa paradisiaca L.) DI PUSAT PELATIHAN PERTANIAN PEDESAAN SWADAYA MITRA MANDIRI KUBURAYA
Authors: Sangkala  , Sunardi  , Mona
Published: May 2023

Tumbuhan pisang merupakan jenis tanaman yang dapat dibudidayakan baik di iklim tropis juga sub tropis. Kegiatan analisa usaha sangat penting dilakukan untuk mengetahui usaha tersebut dapat menguntungkan atau tidak sehingga dapat diketahui usaha budidaya pisang kepok layak atau tidak untuk dijadikan suatu usaha. Penelitian ini dilaksanakan di Pusat Pelatihan Pertanian Pedesaan Tani Mitra Mandiri (P4S Mitra Mandiri), yang berlokasi di Jalan Trans Kalimantan Km 21, Kubu Raya P4S Mitra Mandiri merupakan Pusat Pelatihan Pertanian dan Pedesaan Swadaya (P4S) Mitra Mandiri yang bergerak dibidang pertanian.. Data-data yang terkait analisa kelayakan terdiri dari data investasi dan data variabel. Perhitungan  data investasi dilakukan dengan menghitung biaya penyusutan, penerimaan, keuntungan  dan menganalisis kelayakan usaha. Investasi yang dibutuhkan untuk merealisasikan usaha budidaya pisang kepok seluas 1 Ha yaitu sebesar Rp 4.030.000,00. Biaya variabel untuk tahun pertama. Penerimaan kotor dari usaha budidaya pisang kepok seluas 1 Ha dalam jangka waktu dua tahun yaitu sebesar Rp 108.000.000. Modal budidaya pisang kepok sebesar Rp 108.000.000 dapat memperoleh keuntungan Rp 79.055.000/Ha dalam jangka dua tahun. Total biaya sebanyak Rp 28.945.000 dan harga jual sebesar Rp 3.000, maka untuk mencapai titik impas jumlah pisang paling minimal yang terjual yaitu sebanyak 9.648 /Ha dalam jangka waktu dua tahun
Pengaruh Penambahan Madu Sebagai Sumber Karbon terhadap Fermentasi Spontan Biji Kopi Arabika Di Kabupaten Bantaeng
Authors: Yuli Sasmita  , Sukainah Andi , Wijaya Muhammad
Published: May 2023

Tujuan penelitian ini untuk mengetahui pengaruh penambahan madu selama fermentasi terhadap kadar kafein dan kandungan mutu kimia biji kopi arabika yang dihasilkan. Penelitian dilakukan dalam bentuk percobaan dengan menggunakan Rancangan Acak Lengkap (RAL) dengan penambahan konsentrasi perlakuan berdasarkan berat keseluruhan kopi : air (1:1) yaitu kontrol, 2%, 4%, 6%, 8%, 10%, 12% dan 14%. Pengamatan dilakukan saat fermentasi yaitu ALT, TAT dan nilai pH serta kadar air dan kadar kafein biji kopi. Perlakuan dengan penambahan madu yang memiliki kadar kafein terendah akan dilakukan analisis mutu pada biji kopi seperti kadar abu, kadar protein, total asam tertitrasi, nilai pH, aktivitas antioksidan, polifenol, total gula dan gula reduksi. Data analisis menggunakan aplikasi SPSS 22. Hasil penelitian menunjukkan bahwa penambahan konsentrasi madu berpengaruh terhadap kadar kafein dan kadar air biji kopi Arabia. Perlakuan terbaik yaitu penambahan konsentrasi madu 14% dengan nilai kadar kafein 2,26%, TAT 0,39%, nilai pH 3,96%, kadar air 9,63%, kadar abu 3,50%, kadar protein 0,48%, aktivitas antioksidan 18,47%, polifenol 82,19%, total gula 4,13% dan gula reduksi 1,56%.
A Systematic Review of Consumer Perception: Factors Affecting Green Shopping Bags
Authors: V. Ashwini , Aithal P. S.
Published: May 2023

Purpose: The harmful impacts of plastic pollution on the world's present climate. The vast majority of plastic waste accumulates on land, on beaches, and in the ocean. Green shopping bags are in high demand in the market and are the greatest alternative to plastic carry bags. Eco-friendly bags are long-lasting, plastic-free, reusable, and produced from recycled materials. Eco-friendly shopping bags are immensely popular among both shops and customers due to their low cost, lightweight, and environmental friendliness. The study addresses the factors that influence customer perceptions of eco-friendly shopping bags. Design/Methodology/Approach: This study relies on secondary sources gathered from a variety of sources, including case studies, journal articles, magazines, books, and internet searches. Findings/Result: The study's main findings show that disposing of plastic bags in landfills causes a variety of environmental risks. Green marketing helps to preserve the environment for future generations. Customers are willing to pay a premium for ecologically friendly stuff. Green handbags are the most ecologically friendly substitute for plastic bags. Eco-friendly shopping bags may help businesses and organizations advertise their brands more effectively. Manufacturers must overcome the disadvantages of eco bags if they wish to increase the usage of green bags. The general public should be educated on the benefits of adopting green shopping bags. Originality/Value: The study highlights assist manufacturers, entrepreneurs, and retailers in understanding the effectiveness of employing green shopping bags for long-term environmental benefits and high demand in the present market. Businesses became green and began utilizing green marketing techniques in response to increased demand from customers concerned about their health and the environment. Green shopping bags encourage individuals to adopt sustainable lifestyles and thereby actively help achieve sustainable development goals. Type of Paper: Literature Review
Mikrobiološka dijagnostika infekcija uzrokovanih
bakterijama
Ureaplasma urealyticum i Mycoplasma hominis
Authors: Kavelj Tina , Novak Anita
Published: May 2023

Cilj rada: Odrediti učestalost infekcija uzrokovanih M. hominis i U. urealyticum u KBC-u Split od 1.1.2020. do 31.12.2020. te odrediti osjetljivost navedenih izolata na antibiotike u istom periodu.Materijali i metode: Istraživanje je obuhvatilo podatke o pacijentima s dokazanom M. hominis ili U. urealyticum u navedenom razdoblju. Podatci su prikupljeni u Kliničkom zavodu za mikrobiologiju i parazitologiju, Kliničkog bolničkog centra (KBC) Split. Kao dijagnostička metoda koristio se komercijalni set za kultivaciju urogenitalnih mikoplazmi MYCOFAST RevolutioN, podijeljen u dvije faze testiranja.Rezultati: Klinički zavod za mikrobiologiju i parazitologiju u Splitu zaprimio je 638 uzoraka iz urogenitalnog trakta sumnjivih na infekciju urogenitalnimi mikoplazmama. Od toga je u 7% (ukupno 45 uzoraka) dokazana U. urealyticum te u 0,5% (ukupno 3 uzorka) M. hominis. Ureaplazme najčešće uzrokuju infekcije spolnog sustava i to u žena u generativnoj dobi. Većina testiranih izolata ureaplazmi bila je osjetljiva na doksicikin (94,4%), eritromicin (82,9%), moksifloksacin (80,5%), levofloksacin (77,8%) i tetraciklin (76%), a rezistentnana klindamicin (95,8%). Zbog malog broja mikoplazmi testiranih na antibiotike, uzorak nije repre-zentativan za statističku analizu osjetljivosti izolata na antibiotike.Zaključci: Rezultati ovoga istraživanja ukazuju na najveću pojavnost urogenitalnih mikoplazmi u žena reproduktivne dobi, što naglašava značaj rane dijagnostike i liječenja, kako bi se pravodobno spriječile komplikacije u trudnoći i postpartalnom razdoblju. Iako je većina izolata dobro osjetljiva na tetracikline i makrolide, potrebno je stalno testiranje osjetljivosti izolata na antibiotike zbog sve veće pojave i rasta rezistencije u svijetu.
Ultrazvuk
prsišta: vrijedna dijagnostička metoda
Authors: Petrić Duvnjak Jasna
Published: May 2023

Dugi se niz godina smatralo da ultrazvuk nije pogodna metoda prikaza promjena prsnog koša. Ultrazvuk prsnog koša je osobito primjenjiv u djece jer imaju tanku stijenku prsnog koša, a promjene na plućima većinom dopiru do pleure. Jednostavno ga je primijeniti uz krevet bolesnika. Ultrazvuk prsišta je dijagnostička metoda razvijena od liječnika kliničara za daljnju kliničku uporabu. Postoje tipične ultrazvučne promjene (“artefakti”) koje je potrebno prepoznati na ultrazvuku prsišta. Pregledavanje mora biti sustavno, uvijek istim redoslijedom, kako bi se dobile mjerljive i točne informacije o plućnoj patologiji. Ultrazvuk prsišta pogodan je za praćenje i rano otkrivanje komplikacija bolesti. Ultrazvuk prsišta može se lako uključiti u dijagnostički algoritam u svrhu smanjenja izloženosti ionizirajućem zračenju. Klinička uporaba ultrazvuka prsišta može omogućiti brže postavljanje ispravne dijagnoze i liječenja, što dovodi do poboljšanja ishoda bolesti.