bluuebunny/crossref_metadata_2025 huggingface dataset:
VALUE AND IMPORTANCE OF PHILOSOPHY COURSES WITHIN NON-PHILOSOPHY STUDIES: STUDENTS’ PERSPECTIVE
Authors: Dimić Zoran , Ristić Gorgiev Slađana , Jovanović Milan
Published: March 2022

Do non-philosophy university students consider philosophy to be important for their education? In this paper, we present the results of the empirical research that we have conducted in order to address this question. The study included 151 participants and was based on an online questionary. Our approach was focused on students’ evaluation of the role and significance of the philosophical courses they have attended. The results indicate that students highly regard philosophy as valuable and beneficial not only for general but also for their professional education. We take those results to offer a strong argument against the current trend of decline and reduction of philosophical education in high schools and universities of the Republic of Serbia.
ŠKOLA KAO VASPITNA SREDINA IZ PERSPEKTIVE UČENIKA STARIJEG ŠKOLSKOG UZRASTA
Authors: Milosavljević Đukić Tatjana , Bogavac Dragana , Mikić Andrijana
Published: March 2022

Starting from the fact that primary school is a very important factor for the education of young people, we were interested in how senior primary school students see school as an educational environment, which is the goal of our research. The research was conducted on a sample of 309 eighth grade primary school students in ten cities in the Republic of Serbia. In this research, a descriptive method was used, and the Questionnaire for assessing the educational function of school from the perspective of senior primary school students was designed and used as the instrument. Statistical procedures such as frequencies and percentages, mean with corresponding standard deviation were used. Differences were tested with the Student's t-test. The obtained research results show a more complete picture of the educational role of school from the perspective of senior primary school students in the Republic of Serbia. The research findings can be used for a deeper observation of this very important pedagogical problem, in order to work on greater engagement, involvement in creating and maintaining a more positive attitude of students towards the school environment.
Formulation and Evaluation of review on epilepsy and its management
Authors: Kotkar Vikas Govind , Bagwan Prof. Latif , Hingane Dr. L. D.
Published: March 2022

Abstract: In this project work we speak about different types of epilepsy. Epilepsy is 4th most common neurological disorder affecting 65 million peoples worldwide, according to epilepsy foundation of America, he found that approximately 45000 peoples are dead due to epilepsy. It is categorized into two main types i:e partial seizure( affecting small portion of brain) generalized seizures( covering all portion of brain). Several etiological factor responsible for causing epilepsy such genetic, CNS infection, metabolic disorders, miscellaneous. Epilepsy is caused due to imbalance between glutamate and GABA neurotransmitters. Abnormal jerking movement, confusion, fatigue, repetitive blinking are some common symptoms of epilepsy. While diagnostic test such as EEG, CT scan, PET scan, MRI and other treatment such ketogenic diet, vagus nerve stimulation, help to many people of all age who live with epilepsy. Today’s several antiepileptic drugs are available such as phenytoin, carbamazepine, ethosuximide, phenobarbital, may help to treat all types of epileptic seizures. So, there is need to continue research on it to treat all epileptic problems worldwide.
Detecting fraud of financial statement through pentagon's fraud theory
Authors: Murtado Ali , Andru Achmad , Darmayanti Agustina , Adriadi Krisno
Published: March 2022

This study aims to detect fraudulent financial statements using the Pentagon's fraud theory. The fraud pentagon theory is projected with financial targets, financial stabilities, external pressure, institutional ownership, ineffective monitoring, quality external auditors, change in auditor, capability, and CEO arrogancy. This study uses a quantitative research design and secondary data from 44 state-owned enterprises. The multiple regression analysis shows that external pressure and institutional ownership affect fraudulent financial statements. While financial targets, financial stabilities, ineffective monitoring, quality external auditors, change in auditor, capability, and arrogancy do not affect fraudulent financial statements.
Implementasi Algoritma Genetika Dalam Optimasi Jarak Tempuh Pendistribusian Produk Lokal Provinsi NTT
Authors: Tavares Olivia Maria Inacio , Susanto Agung , Budiman Setiawan , Kusrini Kusrini , Maulina Dina
Published: March 2022

Kegiatan distribusi produk dalam mensukseskan tujuan pemasaran sudah menjadi kegiatan utama yang wajib untuk dipersiapkan secara matang oleh pihak produsen. Adapun dalam proses distribusi, terdapat faktor utama yang perlu diperhatikan diantarannya besaran jarak serta waktu tempuh, dengan memperhatikan faktor tersebut tentu akan memberikan sumbangsih positif dalam proses pendistribusian produk. Jarak dan waktu tempuh yang tidak diperhitungkan dengan baik mampu menyebabkan kerugian akibat over time dan over budged. Dalam menyelesaikan masalah tersebut dibutuhkan suatu formulasi untuk mengoptimalkan jarak dan waktu distribusi. Permodelan kasus ini akan diimplementasi untuk mengoptimalkan kegiatan pendistribusian produk lokal dari Ibu Kota Provinsi NTT ke 4 kota lainnya yang menjadi titik pusat distribusi di wilayah NTT. Dengan tujuan menghasilkan rute perjalanan teroptimal, maka peneliti mengusulkan untuk menggunakan Algoritma Genetika. Hasil penelitian didapatkan dengan memperhitungkan jarak tempuh untuk kelima Kota sekitar Provinsi Nusa Tenggara Timur yaitu Kota Kupang, Kota Soe, Kota Kefa, Kota Atambua dan Kota Besikama setelah melalui perhitungan menggunakan Algoritma Genetika. Pengujian dilakukan secara berulang kali untuk menemukan rute terpendek. Hasil pengujian menunjukkan semakin banyak jumlah populasi kromosom yang dibangkitkan maka akan semakin sedikit jumlah iterasi yang dibutuhkan untuk mendapatkan jarak tempuh terpendek dan teroptimal. Pengujian hasil keluaran akhir menggunakan program Matlab 2016 yang dapat dijadikan sebagai rute acuan untuk pendistribusian produk lokal ke depannya.
Hydrodynamic surfaces with midsection in the form of Lame curve
Authors: Karnevich Valery V.
Published: March 2022

General representation of ship geometry is given by the method of slicing the ship hull by three mutually perpendicular planes: vertical symmetry plane which runs along the middle of hull width, horizontal plane which divides the hull into underwater and abovewater parts, and vertical plane perpendicular to the other two which coincides with midsection. By taking the same three predefined sections of the theoretical hull shape, it is possible to obtain three algebraic surfaces of different order, which are called hydrodynamic in this article. By introducing alphabetic parameters to signify orders of ship skeleton main curves and then by giving them various numerical values, it is possible to consider a large number of hull shapes, having only three explicit surface equations. Method of deriving the equations, obtained by other authors, using only three explicit algebraic equations is demonstrated. The proposed technique is illustrated on six new ship hull shapes.
ANCAMAN PIDANA MATI BAGI PELAKU TINDAK PIDANA PENGEDAR NARKOBA MENURUT FATWA MUI DAN UNDANG-UNDANG NARKOTIKA
Authors: Soleha Diyah Ayu
Published: March 2022

This study aims to answer the problem currently being disputed, namely the pros and cons of imposing capital punishment on drug traffickers in Indonesia. Given the rampant crime of drug abuse and even increasing every year, of course it needs sanctions and strict rules in solving the case. The impact that will be caused is very negative for the next generation of the nation. The focus of this research is about how sanctions for drug dealers and how these sanctions if reviewed through the Fatwa MUI. The research method used in this study is a qualitative research method. Using secondary data sources consisting of primary legal material and secondary legal material, the primary legal material in this study is Law Number 35 of 2009 concerning narcotics abuse, and Fatwa MUI Number 53 of 2014 concerning the death penalty for drug dealers. Whereas secondary legal material consists of books which are relevant to research, journals, as-sunnah, ijma 'of the scholars. The results of this study that criminal sanctions for drug dealers according to the Narcotics Act consists of 2 crimes namely imprisonment and fines, and capital punishment. According to the Fatwa MUI drug dealers were given ta'zir sanctions. And the death sentence for drug dealers is in line with the Fatwa MUI No. 53 of 2014.Keywords: Drug dealers; sanctions; capital punishment.AbstrakPenelitian ini bertujuan untuk menjawab permasalahan yang saat ini banyak diperselisihkan yakni mengenai pro dan kontra penjatuhan pidana mati terhadap pelaku pengedar narkoba yang diberlakukan di Indonesia. Mengingat begitu maraknya tindak pidana penyalahgunaan narkoba bahkan terus meningkat setiap tahunnya, tentu perlu sanksi dan aturan yang tegas dalam menyelesaikan perkara tersebut. Dampak yang akan ditimbulkan pun sangat negatif bagi generasi penerus bangsa nantinya. Fokus dari penelitian ini yaitu sanksi bagi pengedar narkoba ditinjau melalui Undang-Undang Narkotika dan Fatwa MUI. Metode penelitian yang digunakan dalam penelitian ini adalah metode penelitian kualitatif. Menggunakan sumber data sekunder yang terdiri dari bahan hukum primer dan bahan hukum sekunder, bahan hukum primer dalam penelitian ini Undang-Undang Nomor 35 Tahun 2009 tentang penyalahgunaan narkotika, dan Fatwa MUI Nomor 53 Tahun 2014 tentang hukuman mati bagi pengedar narkoba. Sedangkan bahan hukum sekunder terdiri dari buku-buku yang relevan dengan penelitian, jurnal, as-sunnah, ijmaâ€™ para ulama. Hasil dari penelitian ini bahwa sanksi pidana bagi pengedar narkoba menurut Undang-Undang Narkotika terdiri dari 2 pidana yaitu pidana penjara dan denda, dan pidana mati. Menurut Fatwa MUI pengedar narkoba diberikan sanksi taâ€™zir. Penjatuhan pidana mati bagi pengedar narkoba sudah selaras dengan fatwa MUI No. 53 tahun 2014.Kata Kunci : Pengedar narkoba; sanksi; pidana mati.Â
ANALISIS HUKUM PERKAWINAN ANTARA ORANG PENGIDAP HIV/AIDS DALAM MUZAKARAH MUI No. 18 TAHUN 1996 (Studi Kasus Di KDS Soloplus)
Authors: Muhadi Muhadi
Published: March 2022

Marriage is one of the religious orders for people who are able to do it immediately. Marriage is one of the Sunnatullah that applies to all of its creatures, especially humans. Marriage of HIV positive people is certainly different from marriage of healthy people in general, HIV positive household life is not as smooth as marriage in general, they will face different situations with normal partners, such as stigma and discrimination, the threat of contracting a virus from a partner, and boredom in taking ARV drugs. The purpose of this study was to know the household life of people living with HIV / AIDS in KDS Soloplus and the relevance of the marriage in Muzakarah MUI review No. 18 of 1996. This research is a qualitative field study. Data collection techniques using observation, interviews, and documentation. Data Analysis Techniques using descriptive analysis. The results of this study indicate that the household situation of people living with HIV / AIDS in the Soloplus peer group there are several problems that have been successfully observed and investigated including saturation of ARV drugs, fear of viruses that can infect their partners, adherence to religion, stigma and discrimination, and prohibitions on marriage people with HIV.Keywords: Marriage; Marriage of PLWHA; Household Situation of PLWHA Couples.Â AbstrakPernikahan adalah salah satu perintah agama bagi orang-orang yang dapat melakukannya dengan segera. Pernikahan adalah salah satu Sunnatullah yang berlaku untuk semua makhluknya, terutama manusia. Perkawinan orang HIV positif tentu berbeda dengan perkawinan orang sehat pada umumnya, kehidupan rumah tangga HIV positif tidak semulus perkawinan pada umumnya, mereka akan menghadapi situasi berbeda dengan pasangan normal, seperti stigma dan diskriminasi, ancaman tertular virus dari pasangan, dan kebosanan dalam minum obat ARV. Tujuan dari penelitian ini adalah untuk mengetahui kehidupan rumah tangga orang yang hidup dengan HIV / AIDS di KDS Soloplus dan relevansi perkawinan dalam tinjauan Muzakarah MUI No. 18 tahun 1996. Penelitian ini adalah studi lapangan kualitatif. Teknik pengumpulan data menggunakan observasi, wawancara, dan dokumentasi. Teknik Analisis Data menggunakan analisis deskriptif. Hasil penelitian ini menunjukkan bahwa situasi rumah tangga orang yang hidup dengan HIV / AIDS dalam kelompok sebaya Soloplus ada beberapa masalah yang telah berhasil diamati dan diselidiki termasuk saturasi obat ARV, takut virus yang dapat menginfeksi pasangan mereka, kepatuhan terhadap agama, stigma dan diskriminasi, dan larangan menikah orang dengan HIV.Kata kunci: Perkawinan; Perkawinan ODHA; Situasi Rumah Tangga Pasangan ODHA.Â
JUAL BELI BIBIT PADI SIAP TANAM SISTEM PATOK DALAM PERSPEKTIFâ€˜URF (Studi Kasus di Desa Pepe, Ngawen, Klaten)
Authors: Nurmansyah Rinaldi Hermawan
Published: March 2022

This study discusses the muamalah problem in Pepe Village, Ngawen District, Klaten Regency in the form of buying and selling rice seeds ready for planting using the patok system. The data of this study were obtained through interviews with parties involved in the sale and purchase of seeds, observation and documentation. By using the theory of buying and selling about pillars and terms of sale and purchase as well as the â€˜urf Â theory, this study found that in the contract used in the sale and purchase of rice seeds is one patok. One rice field patok owned by each buyer is not the same and the price is for each fixed patok. This results in the seller needing to plant new rice seeds to meet the shortage of the rice seedlings if the seller estimates the number of rice seeds is lacking. But according to adat in the village, a rule has been applied if in the sale and purchase using the stakes system there is a shortage of rice seeds then it has become the responsibility of the seller. The habits carried out by the Pepe Village community are included in the category â€˜urf s}ahi>h which can be taken into consideration in establishing the law.Keywords: Buy and Sell; Rice Seeds; Patok; â€˜Urf.AbstrakPenelitian ini membahas tentang persoalan muamalah yang ada di Desa Pepe, Kecamatan Ngawen, Kabupaten Klaten berupa jual beli bibit padi siap tanam yang menggunakan sistem patok. Data penelitian ini diperoleh melalui wawancara dengan para pihak yang terkait dalam jual beli bibit, observasi dan dokumentasi. Penelitian ini menggunakan teori jual beli tentang rukun dan syarat jual beli serta teori â€˜urf, penelitian ini menemukan bahwa dalam akad yang digunakan dalam pelaksanaan jual beli bibit padi adalah satu patok. Satu patok sawah yang dimiliki setiap pembeli tidak sama dan harganya untuk setiap patok tetap. Hal ini mengakibatkan penjual perlu menyemaikan bibit padi baru untuk memenuhi kekurangan bibit padi tersebut apabila penjual dalam menaksirkan jumlah bibit padi kurang. Namun menurut adat yang ada di Desa tersebut, sudah berlaku sebuah aturan apabila dalam jual beli dengan menggunakan sistem patok terjadi kekurangan bibit padi maka sudah menjadi tanggung jawab pihak penjual. Kebiasaan yang dilakukan oleh masyarakat Desa Pepe tersebut termasuk dalam kategori â€˜urf s}ahi>h yang mana bisa dijadikan pertimbangan dalam menetapkan hukum.Kata kunci: Jual Beli; Bibit Padi; Patok; â€˜Urf.
INTEGRASI CORPORATE SOCIAL RESPONSIBILITY (CSR) DAN ZAKAT MAAL PADA PERUSAHAAN
Authors: Firmansyah Kholis
Published: March 2022

Companies in Indonesia are responsible for contributing to the state and society, including providing Corporate Social Responsibility (CSR) funds according to the constitution UU No.40 Tahun 2007, pay taxes according to the constitution UU No.36 tahun 2008 and pay zakat according to the constitution UU No.23 Tahun 2011 (for Muslim-owned companies). so, the company has three obligations, namely : issuing CSR, paying taxes and zakat. In this case the author will examine how the implementation of PT. Telekomunikasi Indonesia, Tbk. in integrating the obligation to channel CSR funds with Zakat Maal. This research is a qualitative research, with an exploration method, and is descriptive in nature. Methods of data collection by means of observation, interview, focus group discussion and documentation. And the data analysis method used in this research is descriptive analysis method. The result of this research is PT. Telekomunikasi Indonesia, Tbk. Witel Sidoarjo integrates the obligation to issue Corporate Social Responsibility (CSR) funds and Zakat Maal by calculating: 3% x (Current Assets - Accounts Payable). Then from the 3%, 2% is allocated in the CSR program and 1% is allocated in the Zakat Maal program. Then distributed to the community with partnership, education, health, social and religious programs.
Equatorial to Polar genomic variability of the picoalga Bathycoccus prasinos
Authors: Leconte Jade , Timsit Youri , Delmont Tom O , Lescot Magali , Piganeau Gwenaël , Wincker Patrick , Jaillon Olivier
Published: March 2022

Phytoplankton plays a fundamental role in the ecology of ocean systems
and is the key player in the global carbon cycle. At a time of global
warming, understanding the mechanisms of its adaptation to temperature
is therefore of paramount importance. Cosmopolitan planktonic species
abundant in different marine environments provide both a unique
opportunity and an efficient methodological tool to study the genomic
bases of their adaptation. This is the case for the eukaryotic picoalga
Bathycoccus prasinos, whose genomic variability we chose to study in
temperate and polar oceanic waters. Using multiple metagenomic datasets,
we found that ~5% of B. prasinos genomic positions are
variable, with an overwhelming majority of biallelic motifs. Cold and
temperate waters are clearly associated with changes in variant
frequencies, whereas in transitional waters we found more balanced
polymorphism at most of these positions. Mesophilic and psychrophilic
gene variants are distinguished by only a few amino acid changes located
at positions critical for physical and functional protein properties.
These results provide new information on the genomic diversity of a
cosmopolitan eukaryotic planktonic species and suggest “minimal
mutational strategies” related to the properties of specific proteins
at different temperatures.
Concomitant knockout of target and transporter genes in filamentous fungi by genome co-editing
Authors: Tamano Koichi
Published: March 2022

In most countries, genetically modified microorganisms are not approved
for use for fermentation in the food industry. Therefore, random
mutagenesis and subsequent screening are performed to improve the
productivities of valuable metabolites and enzymes as well as other
specific functions in an industrial microbial strain. In addition,
targeted gene knockout is performed by genetic recombination using its
enzyme genes as selectable markers to maintain self-cloning status.
However, random mutagenesis has a drawback as it does not guarantee
improvement of the targeted function. Conversely, self-cloning is rarely
used to breed an industrial microbial strain. This is probably because a
self-cloning strain is similar to a genetically modified strain, as both
undergo homologous recombination, although exogenous genes are not
introduced. In this article, I discuss the usefulness of genome editing
technology as a substitute for conventional techniques to breed
filamentous fungal strains. This article particularly focusses on
“genome co-editing,” a genome editing technology used for knocking out
two genes concomitantly, as reported in Magnaporthe grisea and
Aspergillus oryzae. Especially, when genome co-editing is applied to a
target gene and a membrane transporter gene that aid the entry of toxic
compounds into cells, the resulting clone can be categorized as an
autotrophic and non-genetically modified clone. Such a clone should
easily apply to industrial fermentation without being restricted by a
genetically modified status. Genome co-editing will also be used to
construct mutant strains with multiple target gene knockouts by
eliminating multiple membrane transporter genes. This could
substantially improve the productivities of valuable metabolites and
enzymes in a stepwise manner. Thus, genome co-editing is considered a
potentially powerful method to knock out single or multiple target genes
that can contribute to the breeding of filamentous fungal strains in the
food industry.
EQUIPPING HOUSEHOLDS WITH DURABLE GOODS IN THE AGE OF THE INTERNET OF THINGS
Authors: Kolny Beata
Published: March 2022

The purpose of this paper is to examine equipping households with some smart devices and to discuss the advantages of having and using them in households, as well as the reasons why households do not purchase these devices. The paper was written on the basis of secondary and primary sources of information. Direct research was conducted using the technique of an online survey on a sample of 620 representatives of households living in Poland in 2021. The results obtained indicate that households most often have house electronic devices, i.e., smart TVs and multimedia players. As for household appliances, most respondents possessed a smart vacuum cleaner, followed by a washing machine and a refrigerator. The most popular smart home automation devices are lighting (light bulbs) and heating (thermostats). The main advantage of using smart devices is to facilitate everyday activities by controlling devices from anywhere, whereas the reason why households do not purchase such devices is their high price and no need to possess them.
ESTIMATION OF BANKRUPTCY RISK BASED ON AUDIT OPINIONS: CASE STUDY IN ROMANIA
Authors: Mădălin-Mihai Moțoc
Published: March 2022

In a world focused on growth, capital accumulation and continuous economic development, it is important to build safety levers to ensure that investors see a return on their investments. Media outlets, brokers, financial institutions and the business environment are now referring, more than ever, to investment policies not only of companies, but also of individuals with sustainable economic capital. Platforms such as Forex, e-Toro, Capital.com, Libertex, cryptocurrency trading platforms and free access to the Stock Exchange now make it extremely easy for third-party investors, with promises of significant returns in a very short period of time. But are all these exhortations and “marketing guns” directed at individuals’ finances devoid of speculative interest? The purpose of this paper is to identify a model of bankruptcy risk estimation that is based on the opinions of audit companies regarding the reasonableness of annual financial statements and their associated fraud risk. This paper presents an empirical approach to the insolvency phenomenon, based on the opinions of the auditors who classify the audited companies as having an associated fraud risk. The study was conducted at the level of companies on the main trading market of the Bucharest Stock Exchange. The results show that an audited company as having classified by auditors as an associated fraud risk is at least one step closer to bankruptcy, as opposed to companies without an assessed risk of associated fraud. The ability of audit companies to contribute to bankruptcy risk estimation models by flagging fraud risk, based on analysis of financial statements, represents a recurring problem in the specialized literature. This paper brings added value in establishing viable models of bankruptcy risk for big companies on the market.
Optimization of the slaughterhouse water treatment rate by a new Marinobacter carbonoclasticus SF and its biosurfactant
Authors: Mihoubi Nadia , Ferhat Samira , Alouaoui Redha , Ibrir Abdellah , Nedjhioui Mohamed , Badis Abdelmalek
Published: March 2022

The aim of this study consists of the production of a bio-surfactant from a new bacterial strain, Marinobacter hydrocarbono clasticus SF (96.76 % similarity) isolated from soil contaminated by hydrocarbons in Hassi-Messaoud (Southern Algeria) to treat liquid effluent from slaughterhouse water. The characteristics of organic matter biodegradation tests were discussed. Despite the high pollutant load and the unfavorable physicochemical composition of the effluent, the specific growth rate of the isolated strain after 10 days of incubation in the range of 0?30 g L-1 of NaCl was at neutral pH 7.4 and temperature of 45?C. The best bio-surfactant production yield was obtained after 72 h of incubation and under the optimal production conditions such as diesel as carbon source, ammonium chloride as nitrogen source, and a C/N ratio of 5. The bio-surfactant produced is of glycolipid type with a low critical micellar concentration (CMC), good emulsifying power, and chemical and functional stability. Significant pollutant removal efficiency was obtained using the bacterial strain (up to 82 %) and the bio-surfactant (up to 96 %). Several anions, such as nitrates, phosphates, ammonium, and suspended solids, were measured.
A novel technique for solving two-person zero-sum matrix games in a rough fuzzy environment
Authors: Jangid Vinod , Kumar Ganesh
Published: March 2022

This study proposes a novel way to deal with uncertainty in a two-person zero-sum matrix game with payoffs expressed as fuzzy rough numbers. Complete and reasonable solutions to these types of games are obtained. In this research we develop two linear programming models with upper and lower approximation intervals of fuzzy rough numbers and handle multi-objective crisp linear programming models by incorporating trapezoidal fuzzy rough numbers as payoffs. To provide each opponent with the optimal strategy and value of the game, the usual simplex approach is applied. Finally, two numerical examples demonstrate the matrix game outcomes using Wolfram Cloud.
The use of chemical plant protection products in field vegetable farms in a central industrial vegetable growing area in Finland
Authors: Räsänen Kati , Hannukkala Asko , Kurppa Sirpa , Aaltonen Marja , Rahkonen Anne , Kukkonen Jussi , Vänninen Irene
Published: March 2022

Progress in the reduction of environmental and health risks of PPPs (plant protection products) using Integrated Pest Management (IPM) in the EU needs to be gauged. Here, we report, for the first time, the exact quantities of PPP used in carrot, potato, swede, and fresh pea production in southwestern Finland from 2003 to 2019. Fresh peas and swede represent exceptionally low or decreasing use of PPPs, respectively. The number of treatments per field showed an increasing trend for fungicides used on potato, despite per unit area treatments have not increased. Furthermore, for carrots, insecticide and herbicide spray frequencies increased more than treatment volumes. The results of this study form a basis for analyzing ecotoxicological risks of PPP use in the studied crops because usage and spray frequencies alone do not convey the risk levels accurately. Research needs to be continued to better guide the recording of farmers’ plant protection activities and corresponding analysis to verify the impacts of IPM implementation.
Polymorphisms in Exon 13 of Angiotensin-Converting Enzyme Gene among Hypertensive Patients in Sudan
Authors: Osman R. T. , Hassan D. A. , Elamin M. I. , Elamin M. , Mursi D. , Salih M. A. M.
Published: March 2022

Background: The identification of the critical regions within angiotensin-converting enzyme (ACE) gene which predict hypertension and/or influence ACE activity would have significant implications for precision medicine. Studies investigating the association of ACE gene polymorphisms and the risk of developing hypertension have yielded inconsistent results.

Objective: The aim of the study is to identify single nucleotide polymorphisms (SNPs) or haplotype markers in exon 13 of ACE gene and their association with essential hypertension in a sample of Sudanese population.

Methods: Amplified fragments of 550bp across exon 13 of ACE gene were outsourced to the Macrogen Company, Seoul, South Korea for sequencing. Finch TV program was used to view the chromatogram. Gene sequences were translated into amino acid sequence, using GeneMark version 4.25. The structural effect of a point mutation in a protein sequence was analyzed using PROJECT HOPE online website. Linkage disequilibrium between polymorphic variants was determined using Haploview v4.2.

Results: Seven polymorphisms of ACE gene were identified in the sequenced fragments: four exonic SNPs (Rs4316, rs4317, rs4318 and one unreported SNP); an intronic SNP (rs12720723); one SNP at the intronic-exonic boundary site (rs4320); and an intronic I/D (rs4319). Haplotype analysis identified two blocks within 550bp spanning area of the ACE gene. Both blocks were composed of six SNPs: rs12720723; unreported SNP; rs4316; rs4317; rs4318 and rs4319. Each block consisted of five haplotype structures. Block 1 included B1-H1 (GCC), B1-H2 (ACC), B1-H3 (GCT), B1-H4 (GAT) and B1-H5 (AAT), whereas block 2 included B2-H1 (TAC), B2-H2 (CGC), B2-H3 (TAA), B2-H4 (CAC) and B2-H5 (TGC). Rs4317 and rs4318 were in moderate linkage disequilibrium (LD) (D’ value=0.69) among hypertensive patients. Rs4316; rs4319 and rs4320 were in moderate to high LD and displayed relatively high MAF among hypertensive participants.

Conclusion: The results of our study suggest that the 3 SNPs within exon 13 of the ACE gene (rs4316, rs4319 and rs4320) could be genetic markers for developing hypertension as evidenced by the high LD and MAF observed in hypertensive participants. Moreover, rs4318 being in LD with rs4317 could highlight the importance of block 2 in predicting hypertension among blacks.
Rancang Bangun Forklift Autonomous Driving System Menggunakan Arduino
Authors: Nagoro Ignatius Henry Adi , Jati Bias Kumoro , Mutaqin Niki Agastia
Published: March 2022

This study aims to design and build an Arduino Nano-based microcontroller device with a Bluetooth HC-06 module to control a forklift via an Android smartphone. In order to minimize the potential for work accidents, due to operator fatigue which causes physical hazards to operators and the workplace environment. This research was conducted in three stages, namely: a. Mechatronic System Design, b. Making a control system, using the MIT App Inventor app is used to adjust the solenoid valve, c. Tool performance testing. The results showed that the control device can work well up to a distance of 21 meters from the controller and has a delay of 0.16 seconds to 0.3 seconds and resistance to 55 work cycles.

Penelitian ini bertujuan untuk merancang dan membangun perangkat mikrokontroler berbasis Arduino Nano dengan module Bluetooth HC-06 untuk mengendalikan forklift melalui smartphone Android. Agar dapat meminimalisir potensi kecelakaan kerja, akibat kelelahan operator yang menyebabkan bahaya fisik bagi operator dan lingkungan tempat kerja. Penelitian ini dilakukan dengan tiga tahap, yaitu: a. Desain Sistem Mekatronik, b. Pembuatan sisem pengendali, menggunakan Aplikasi MIT app Inventor digunakan untuk mengatur katup solenoid, c. Pengujian kinerja alat. Didapatkan hasil penelitian bahwa perangkat kendali dapat bekerja dengan baik hingga jarak 21 meter dari kontroler dan memiliki delay antara 0,16 detik hingga 0,3 detik serta ketahanan pada 55 siklus kerja.
Influence of Robo Advisory in Investment Decision
Authors: Mulia Rachman Kevin , Sukmadilaga Citra
Published: March 2022

This research is conducted to identify the potential influence of robo advisory, equipped with its features and technological improvements that would aid and assist in investment decision, and compare the relevancy as well as its efficiency to human financial advisor. The objective of this research is to study the discourse of robo advisor’s phase of development and the understanding on behavioral aspect in financial investment, in order to gain proper understanding on investor’s preference in accessing financial advisory services in order to aid in their investment decision. In this respect, the research is conducted through qualitative study, conducted through the process of interviewing a sample of respondents with substantial experience and exposure to financial investment, and had utilized financial advisory services, in which their response are further studied in a case basis through Analytic Hierarchy Process, to find out the relevance and the potency of robo advisors in comparison to human financial advisors in adjusting to investor’s investment decision as well as detecting behavioral investment pattern to determine its preferences to either alternatives of financial advisory. The result of the research indicates stronger preferences to human financial advisors rather than robo advisors, and emphasizes financial literacy as the most influential criteria in determining financial investment decisions.
Evaluasi Tata Kelola Teknologi Informasi Menggunakan Framework COBIT 5 (Studi Kasus: Bidang Perdagangan Dalam Negeri Dinas Perindustrian dan Perdagangan Jawa Timur)
Authors: Az-zahra Tazkia Shabrina
Published: March 2022

Dinas Perindustrian dan Perdagangan (Disperindag) merupakan lembaga yang melibatkan membina dan mengembangakan sektor industri dan perdagangan. Namun, ada beberapa kekurangan pada Dinas Perindustrian dan Perdagangan, salah satunya adalah pencatatan aset yang masih kurang lengkap, karyawan yang kurang disiplin, dan juga ada pembagian pekerjaan yang tidak sesuai karena pegawai sudah diatur oleh Badan Kepegawaian Daerah. Hal ini dapat diperbaiki dengan pembaharuan tata kelola teknologi informasi menggunakan framework COBIT 5 dapat diperoleh persetujuan dan tindakan yang harus diambil agar hal-hal tersebut tidak terjadi KerangkaCOBIT 5 dengan proses domain APO06, APO07, dan BAI09 digunakan pada penelitian ini. Berdasarkan evaluasi yang dilakukan memperoleh informasi tentang bidang perdagangan dalam negeri yang memiliki tata kelola anggaran dan tata kelola sumber daya manusia dan juga tata kelola sumber daya manusia telah menunjukkan hal yang baik dan lebih rumit proses yang telah dilengkapi dengan standar yang dilakukan secara efektif. Tingkat kemampuan pada proses APO06 mengelola anggaran dan biaya mencapai tingkat 3 proses yang ditetapkan seluruh sub-proses pada APO06 juga telah mencapai tingkat 3. Pada proses APO07 mengelola sumber daya manusia rata-rata mencapailevel 2,38 dan BAI09 mengelola aset memiliki tingkat kapabilitas rata-rata sebesar 2,30.
One Health clinic promotes veterinarian-client trust among underserved pet owners and provides learning opportunities for veterinary students
Authors: Powell Lauren , Walsh Meriel , Reinhard Chelsea L , Jankowski Kristin , Watson Brittany
Published: March 2022

OBJECTIVE

To determine the impact of a free One Health clinic with human and veterinary services on the veterinary-client relationship for underserved pet owners. A secondary aim was to understand the experience of veterinary students and volunteers who participated in the clinic.

SAMPLE

78 pet owners, 55 students and 32 volunteers who attended the Delaware Humane Association One Health Clinic between December 2018 and November 2019.

PROCEDURES

Pet owners completed an anonymous questionnaire prior to and following their veterinary appointment regarding their trust in the veterinary profession, feelings of enablement and veterinarian-client concordance. Students and volunteers completed a questionnaire within 72 hours of clinic participation about their perceptions of the educational value of the clinic.

RESULTS

Following the One Health clinic, client trust in the veterinary profession increased significantly (t = –5.50, P < 0.001). Clients also reported high levels of enablement and veterinarian-client concordance. Students and volunteers agreed the clinic was a valuable educational experience (97.7%) and reported increased compassion, enhanced leadership, communication and teamwork skills, and an improved ability to identify social issues and think critically.

CLINICAL RELEVANCE

The results support the utilization of One Health clinics to improve access to veterinary care for underserved pet owners. Clients reported high levels of trust, enablement and concordance following the clinic which could have long-lasting effects on their willingness to seek veterinary care and comply with veterinarians’ recommendations. The positive experiences of students and volunteers also highlights the potential of low-cost veterinary clinics as unique educational experiences.
Chronic nonchylous lymphatic pleural effusion in a bottlenose dolphin (Tursiops truncatus)
Authors: Russell Jennifer P. , Osborn Steven D. , Ivančić Marina , Aristizabal-Henao Juan J. , Bowden John A. , Stedman Nancy , Stacy Nicole I.
Published: March 2022

CASE DESCRIPTION

A 19-year-old male bottlenose dolphin (Tursiops truncatus) presented with inappetence and avoidant behavior.

CLINICAL FINDINGS

Ultrasound revealed a large-volume left-sided pleural effusion, which was consistent with chronic nonchylous lymphatic effusion and mild chronic hemorrhage by cytology. Computed tomography identified ipsilateral rib fractures, atelectasis, nodular pleuritis, marginal lymph node enlargement, and suspected dilation of the thoracic duct and internal thoracic veins. Fifteen lipids were significantly higher in serum of the dolphin as compared with controls (n = 3) using nontargeted lipidomics.

TREATMENT AND OUTCOME

A series of thoracentesis procedures were performed. Follow-up CT demonstrated marked reduction in pleural effusion with persistence of thoracic duct dilation and mass-like areas of pleural thickening. Ultrasonographic resolution of pleural effusion occurred 14 months after presentation; however, recrudescence was noted 5 months later. Over a total of 24 months, 21.52 L of pleural effusion was removed. Despite the presence of pleural effusion, the patient was clinically stable during this time and quality of life was considered good on the basis of continuous animal welfare evaluations. Humane euthanasia was elected following acute clinical decline 27 months after initial diagnosis. Necropsy confirmed severe pleural effusion, chronic severe pleural fibrosis with chronic hemorrhage, and mediastinal fibrosis with entrapped lymph nodes and thymic tissue.

CLINICAL RELEVANCE

Pleuritis and effusion were suspected sequelae of previous rib fractures. To our knowledge, this is the first report of nonchylous lymphatic pleural effusion with repeated pleural drainage and diagnostic imaging for clinical management in a bottlenose dolphin.
Cutaneous manifestations and SARS-CoV-2 infection
Authors: Burczyk Dawid , Jakubowska Michalina , Wcisło-Dziadecka Dominika , Garncarczyk Agnieszka
Published: March 2022

The emergence of the novel SARS-CoV-2 coronavirus and rapid spread of the COVID-19 disease it causes in late 2019 and early 2020 has since led to a global pandemic announced by the World Health Organization (WHO). The pandemic is a steadily growing social, economic, psychological, and health burden. The infection rates worldwide are climbing. COVID-19 is considered a systemic disease, potentially resulting in acute respiratory distress and cardiovascular failure leading to death. Yet, SARS-CoV-2, a novel and still under-studied virus, has been documented to cause a large variety of symptoms, in many cases including cutaneous manifestations.

This paper is a review of medical literature available to date regarding the cutaneous manifestations in the course of SARS-CoV-2 infection. It is also aimed at discussing the significance of dermatological findings for improved diagnosis and treatment of COVID-19 patients. Considering the gravity of the novel coronavirus pandemic, an improved dermatological approach would aid timely diagnosis and effective management of COVID-19, and would facilitate classification of the cutaneous abnormalities observed.
Heavy Metal Content of Pb and Cu in Wideng Crab (Episesarma sp.)
Authors: Saraswati Suprabadevi Ayumayasari , Suryaningtyas Endang Wulandari , Wijayanti Ni Putu Putri
Published: March 2022

The Morosari estuary area is an estuary area consisting of aquaculture areas, mangrove areas, tourist areas, and several large-scale industrial and household activities. This situation causes the entry of waste containing heavy metals (Pb and Cu) into the estuary area. Wideng crab (Episesarma sp.) is one of the biotas that lives in the area and is influenced by the presence of heavy metals (Pb and Cu). This study aims to determine the content of heavy metals Pb and Cu in the mouth of the Morosari River and in the meat of the Wideng Crab (Episesarma sp.). The research was conducted in April – June 2009 and located at the mouth of the Morosari River (Demak). The research method used is a descriptive exploratory method, while sampling using purposive random sampling was conducted at 3 stations. A sampling of Wideng Crabmeat (Episesarma sp.), water, and sediment was carried out every 2 weeks as many as 5 samples and continued with analysis at the Central Laboratory of Kopertis Growth Region IV Semarang. Furthermore, the data obtained were analyzed descriptively. The results of the analysis of the Pb content in water were 0.039 - 0.089 mg/l, and the content in crab meat was 0.175 - 0.335 mg/kg. While the content of Cu in water is 0.024 - 0.055 mg/l, and in crab meat 0.032 - 0.16 mg/kg. The value of heavy metal content in the water has exceeded the quality standard threshold allowed by the Ministry of Environment Number 51 of 2004
Organizing the transition to integrated reporting
Authors: MALINOVSKAYA Natal'ya V.
Published: March 2022

Subject. This article discusses the organizational aspects of the transition to integrated reporting that organizations need to take into account when implementing this prospective corporate reporting model.
Objectives. The article aims to reveal the content of the main stages of development of the plan for the transition to integrated reporting, set out in the Guide of the Value Reporting Foundation, a new global nonprofit organization promoting the concept of integrated reporting and industry-specific sustainability accounting standards, formed as a result of the merger of the International Integrated Reporting Council and the Sustainability Accounting Standards Board.
Methods. The research is based on analysis, synthesis, comparison, generalization, and abstraction.
Results. The article reveals the content of the main stages of the transition to integrated reporting formation, considers a typical roadmap for the transition to integrated reporting, which can become the basis for organizations to develop an individual plan for the transition to this promising model of corporate reporting, taking into account their unique circumstances.
Conclusions. The guide proposed by the Value Reporting Foundation for the transition to integrated reporting is aimed at providing methodological assistance to compilers of a new type of corporate reporting. It summarizes the practical experience of organizations that have implemented the integrated reporting model. It was found that the Value Reporting Foundation's algorithm for the transition to integrated reporting does not contain fundamental innovations in comparison with the proposals previously formulated by Russian scientists. The value of the reviewed guide is that it is presented by the standard-setter of the integrated reporting concept, and it causes greater trust of users, especially those ones who prefer to follow the guidance documents.
Assessment of finance and demand for physical education and sports services in Russia and the Udmurt Republic
Authors: ARKALOV Dmitrii P. , LITVIN Andrei V.
Published: March 2022

Subject. We consider economic aspects of the development of physical culture and sports.
Objectives. The aim is to analyze demand for physical culture and sports services in the Russian Federation as a whole and in the Udmurt Republic in particular.
Methods. We apply general-scientific methods of research.
Results. At the national and regional levels, the study revealed positive dynamics both in the financing of physical culture and sports services, and in the demand for them. The findings enable to state that the goals enshrined in strategies for physical culture and sports development in the Russian Federation can be achieved in the foreseeable future.
Conclusions. It is reasonable to use the results of the study in forecasting the demand for physical culture and sports services.
The modern dynamic model of anti-crisis measures for the national economy of the Russian Federation: An institutional approach
Authors: MANUSHIN Dmitrii V.
Published: March 2022

Subject. This article analyzes the anti-recessionary policy of Russia.
Objectives. The article aims to study and clarify the structure of the dynamic model of anti-recessionary measures, taking into account the latent and overt crises in the national economy, as well as institutional aspects.
Methods. For the study, I used the abstract-logical method.
Results. Based on the review of models of anti-recessionary measures, the article reveals the advantages and disadvantages of the main ones. The article presents an original model of the relationship between the periods of latent and overt crisis and options for implementing anti-recessionary measures in macroeconomics, and it offers a scheme for taking into account the inertia of economic processes.
Conclusions. It is necessary to revise the classical approaches, which provide for countering only overt crises in the Russian economy.
Regional policy: Challenges and conceptual framework
Authors: KHUBAEV Tamerlan A. , BETANOV Viktor T. , KOVALEVA Mariya A.
Published: March 2022

Subject. This article discusses the issues of differentiation of the regions of the Russian Federation by level of socio-economic development.
Objectives. The article aims to define the main conceptual approaches to ensuring sustainable and balanced development of the regions of the Russian Federation.
Methods. For the study, we used the methods of analysis, synthesis, and generalization.
Results. The article presents conceptual provisions on the management of sustainable and balanced development of the regions of the Russian Federation.
Conclusions. Reducing imbalances in the economic and social development of the regions should become the main goal of the spatial development of the Russian Federation.
Human capital components and their impact on the regional economy's development
Authors: POLYANSKAYA Elena V.
Published: March 2022

Subject. This article considers human capital as a factor of labor productivity rise.
Objectives. The article aims to systematize the main structural components of human capital, determine their impact on the regional economy, and typify the Far East regions by public health level.
Methods. For the study, I used a cluster analysis.
Results. The article substantiates the relationship between demographic characteristics, expenditures on education and healthcare, and indicators of economic development of the region. It presents the clustering of the Far East regions in terms of public health indicators for the period from 2000 to 2019.
Conclusions. The regions of the Russian Federation need to adopt targeted programmes to develop human capital and improve its quantitative and qualitative characteristics.