bluuebunny/crossref_metadata_2025 huggingface dataset:
МОДЕЛЮВАННЯ ТЕНДЕНЦІЙ РОЗВИТКУ ІНДЕКСУ УКРАЇНСЬКИХ ОБЛІГАЦІЙ (UB)
Authors: Гнидюк Інна , Тімошенко Наталія
Published: October 2023

Стаття присвячена моделюванню тенденцій розвитку показників індексу українських облігацій UB, що характеризує ринок боргових зобов’язань України. У зв’язку з тим, що на ринку облігацій частка державних боргових інструментів становить 98%, то аналіз індексу UB розкриває стан ринку державних цінних паперів. Період, який аналізується охоплює 2019-2023 роки. Досліджуваний часовий відрізок характеризується різними коливаннями ринку. Притаманні перегріви ринку та компенсаційні періоди глибокого падіння. В дослідженні моделювання проведено на основі вивчення закономірностей за допомогою рядів динаміки. Визначено основні індикатори впливу на ринок: сезонні коливання, політичні зміни та економічна ситуація. Виокремлено вплив воєнного стану в Україні на ринок. На основі цього дослідження змодельована тенденція індексу українських облігацій під впливом виокремлених факторів.
ОСОБЛИВОСТІ ФОРМУВАННЯ ТРАНСФЕРНОГО ПОТЕНЦІАЛУ ТОРГОВЕЛЬНИХ ПІДПРИЄМСТВ
Authors: Князь Святослав , Русин-Гриник Роман , Викрикач Максим
Published: October 2023

Трансферний потенціал є важливим елементом бізнес-стратегії торговельного підприємства, який суттєво впливає на його конкурентоспроможність. Особливості формування трансферного потенціалу торговельних підприємств можуть варіюватись залежно від рівня їх глобалізації та наявності міжнародних бізнес-операцій. У статті наведено та обґрунтовано основні особливості формування трансферного потенціалу торговельних підприємств. Доведено, що формування трансферного потенціалу може мати специфічні особливості в залежності від галузі і виду діяльності підприємства, а саме: якісна базова освіта і навички, наявність кадрового резерву, здатність до інновацій, розвиток міжкультурної комунікації, підтримка від торговельних підприємств, використання сучасних технологій, внутрішня експертиза та розробка професійних стандартів. Загалом, формування трансферного потенціалу є важливим елементом успішної діяльності будь-якої торговельні підприємства, незалежно від її галузі та виду діяльності.
Ancient Women Philosophers: Recovered Ideas and New Perspectives
Authors: O'Reilly Katharine , Pello Caterina
Published: October 2023

Despite the common misconception that ancient philosophy was the domain of male thinkers, sources confirm that ancient women engaged in philosophical activity. Bringing together a collection of essays on ancient women thinkers, with special focus on their ideas and contributions to the history of philosophy, this volume is about the earliest women philosophers, their breakthroughs, and the methods we can use to excavate them. The essays survey the methodological strategies we can use to approach the surviving evidence, retrieve the largely unresearched thought and the original ideas of ancient women philosophers, and carve out a space for them in the canon. The broad focus includes women thinkers in ancient Indian, Chinese, and Arabic philosophy as well as in the Greek and Roman philosophical traditions. The volume will be valuable for a wide range of researchers, teachers, and students of ancient philosophy.

 
Arete of Cyrene and the Role of Women in Philosophical Lineage
Authors: O'Reilly Katharine
Published: October 2023

Arete of Cyrene was daughter and disciple of the founder of the Cyrenaic school and mother and teacher of the figure who codified its principles. Our sources emphasize her as a link in the intellectual chain connecting the school it its Socratic roots, to the detriment of preserving her own philosophical ideas. In this chapter, I make a case for her philosophical contribution to the Cyrenaics, as revealed in a careful reading of the few sources we have. I follow this with methodological reflections on how we might access a figure like Arete. I argue that this task requires and licenses the adoption of severed methodological strategies related to an added open-mindedness to source material. I reflect on how these methodological points contribute to a wider project of recovering the thought of marginalized figures.
Beamforming Array Antenna Technique Based on Partial Update Adaptive Algorithms
Authors: A. Shubber Zahraa , M. Jamel Thamer , K. Nahar Ali.
Published: October 2023

The most important issues for improving the performance of modern wireless communication systems are interference cancellation, efficient use of energy, improved spectral efficiency and increased system security. Beamforming Array Antenna (BAA) is one of the efficient methods used for this purpose. Full band BAA, on the other hand, will suffer from a large number of controllable elements, a long convergence time and the complexity of the beamforming network. Since no attempt had previously been made to use Partial Update (PU) for BAA, the main novelty and contribution of this paper was to use PU instead of full band adaptive algorithms. PU algorithms will connect to a subset of the array elements rather than all of them. As a result, a common number of working antennas for the system's entire cells can be reduced to achieve overall energy efficiency and high cost-effectiveness. In this paper, we propose a new architectural model that employs PU adaptive algorithms to control and minimize the number of phase shifters, thereby reducing the number of base station antennas. We will concentrate on PU LMS (Least Mean Square) algorithms such as sequential-LMS, M-max LMS, periodic-LMS, and stochastic-LMS. According to simulation results using a Uniform Linear Array (ULA) and three communications channels, the M-max-LMS, periodic LMS, and stochastic LMS algorithms perform similarly to the full band LMS algorithm in terms of square error, tracking weight coefficients, and estimation input signal, with a quick convergence time, low level of error signal at steady state and keeping null steering's interference-suppression capability intact.
The Effectiveness of Teaching Reading Skills by Using Cartoon Clips/ Comic Strips in Saudi Context
Authors: Bushra Marium , Tabassum Shabina
Published: October 2023

This paper conducts a study to assess the effectiveness of reading strategies such as using visual aids like comic strips at the secondary school level, KSA. The objective of this research is to highlight the need to use visual aids such as cartoon clips and comic strips, which makes reading comprehension a creative process. This research will be beneficial for EFL reading skill students by better understanding, word processing, and forming relations with the text. The purpose of this research is to show better and more effective techniques implacable in a Saudi Context. In this research, the researcher will use the survey method and a questionnaire as a tool to collect data from a random sample of 50   students. This paper will make suggestions and recommendations for future study and will teach new pedagogical methods through graphic display.
Romance-Themed Novels: Influenced on Relationship Satisfaction
Authors: Garciano Shylyn G. , Cuevas Gloria Con-ui , Geraldizo-Pabriga Maria Gemma , Macabodbod Saira Jay J. , Yu Jaciah Mae B. , Pinote Ma. Jezan A.
Published: October 2023

This paper was conducted to explore romance-themed novels that influence relationship satisfaction. It further described the perception of the reasons given by participants for reading romance-themed novels, the lived experiences of the participants that made them engage in reading romance-themed novels, and the impacts of reading the romance-themed novels on the relationship satisfaction of the participants. This study utilized the qualitative research method. This study's sixteen (16) participants were selected through a case study method. The researcher’s semi-structured interview guide was used in data gathering through interviews. The thematic analysis of Braun and Clarke was used to analyze the qualitative data. Codes, categories, and common themes were identified from the transcript of in-depth interviews. Ten (10) emergent themes were established from the participants’ responses that were classified under three (3) overarching themes that provided answers to the sub-problems. The emergent themes were extracted from the significant statements of the key participants. For the reasons given by participants for reading romance-themed novels, the overarching theme, Reasons of the Informants in Reading Romance-themed Novels, has five (5) emergent themes that were classified as Align Interest, Entertainment, Social Influence, Educational, and Therapeutic. For the participants' lived experiences that made them engage in reading romance-themed novels, the overarching theme, Lived Experiences in Engaging Reading Romance-themed Novels, has two (2) emergent themes classified as On-time availability and Baseline for real-world situations. For reading romance-themed novels on the relationship satisfaction of the participants, the overarching theme is the Impacts of Participants' Relationship Satisfaction; two (2) emergent themes were created, namely Establishing Strong Emotional Bonds and Enlightened Disposition. The findings and recommendations derived from the study were used to disseminate the positive impact of reading romance-themed novels on students' relationship satisfaction.
Quality of Service Analysis on EaTrain Application at A Restaurant on A Train
Authors: Mukti Destanuari Sufia , Hidayati Nurul , Rasyid Abdul
Published: October 2023

One of the services on the train is a dining car that sells food and drinks. However, the current system has problems such as the unclear position and operating hours of the dining car, the lack of menu information, and the difficulty of officers in giving change. The purpose of this research is to make it easier for passengers to order food and drinks, increase the officer’s efficiency in managing menu, and determine the network quality while using the EaTrain application on the train. The EaTrain application was built using android studio with cloud firestore as a database for storing data, and integrated with midtrans payment gateway in making payments. Wireshark software is used to measure the network quality of EaTrain application in train restaurant. The test results show that the EaTrain application can run well on Android 7.0 devices and above. The value of delay, throughput, and packet loss in Quality of Service (QoS) testing while making payments is determined by network quality of each provider. Provider A has average delay of 123ms, packet loss is 10.72%, and throughput is 3974 bps. While provider B has average delay at 1343ms, packet loss is 50.88%, and throughput is 33628 bps.
Analisis Pengaruh Pendapatan Perkapita dan Inflasi terhadap Pengeluaran Konsumsi Rumah Tangga di Provinsi Jambi
Authors: Soleh Ahmad , Daniel Prima Audia , Said Mukti , Agustina Kiki
Published: October 2023

This research aims to determine and analyze developments in per capita income, inflation and household consumption expenditure in Jambi Province. To determine and analyze the influence of per capita income and inflation on household consumption expenditure in Jambi Province. The research method used is secondary data analysis with the research objective being a quantitative descriptive analysis method to answer the first objective, to see the development of per capita income, inflation and household consumption expenditure in Jambi Province during the 2008-2022 period using the development formula. Meanwhile, to see the effect of per capita income and inflation on household consumption expenditure in Jambi Province, multiple linear regression was used with the help of the SPSS software application analysis tool. The results of the analysis carried out concluded, firstly, that the development of per capita income, inflation and household consumption expenditure in Jambi Province for the 2008-2022 period was relatively increasing. Kudua, namely that partially the per capita income variable has a significant effect on household consumption expenditure, while inflation has no significant effect on household consumption expenditure in Jambi Province. However, simultaneously per capita income and inflation have a significant effect on household consumption expenditure with an R-square value of 91.90 percent during the 2008-2022 period.
Low-dose azacitidine, pioglitazone and all-trans retinoic acid is safe in patients aged ≥ 60 years with acute myeloid leukemia refractory to standard induction chemotherapy (AMLSG 26-16/AML-ViVA): results of the safety run-in phase
Authors: Heudobler Daniel , Luke Florian , Hahn Joachim , Grube Matthias , Schlosser Pavla , Kremers Stephan , Sudhoff Thomas , Westermann Jorg , Hutter-Kronke Marie Luise , Schlenk Richard F. , Weber Daniela , Paschka Peter , Zeman Florian , Dohner Hartmut , Herr Wolfgang , Reichle Albrecht , Thomas Simone
Published: October 2023

Not available.
Performances of cattle and goats in some selected areas of Gaibandha district in Bangladesh
Authors: Bashar MA , Mukta SP , Hasan MT , Bhuyan SF , Alam MH , Akhtar MM , Khandoker MAMY
Published: October 2023

The survey was conducted to represent the livestock production scenario and to know the performances of cattle and goats in few selected rural areas of Gaibandha district. The data on productive and reproductive performances of cattle and goats were collected from 102 household within four selected village under Gobindaganj Upazila of Gaibandha district with a pretested survey questionnaire. The collected data were compiled, tabulated and analyzed by student t test. In the study area, about 59% were indigenous cattle and 41% were crossbred cattle. A total of 113 goats were found in the study area of which 82% belongs to Black Bengal goat and the remaining 18% belongs Jamunapari goat. All the livestock (100%) were managed intensively during the spring and rainy seasons. Similarly, almost all livestock (100%) are confined in shed at night, and 45.9% and 54.09% of the livestock population are confined in shed and paddock at day time, respectively. Artificial insemination (AI) is the preferred breeding method for cattle, whereas goats primarily rely on natural mating. Milk yield and lactation period of cow, and mature body weight of both male and female were significantly (P<0.05) higher in crossbred than indigenous cattle. Similarly, age at first kidding, lactation period and kidding interval of does, and mature body weight of buck and does were significantly higher in Jamunapari goats than Black Bengal goats. However, the conception rate and number of kids per kidding were higher in Black Bengal goats than Jamunapari goats. In conclusion, from our results, crossbred cattle and Jamunapari goats are performing better in rural conditions, whereas Black Bengal goats are efficient in producing more offspring at a given time.
Bangladesh Journal of Animal Science 52 (3): 78-84.
Reproductive performance of Jamunapari crossbred using frozen semen
Authors: Rahman MM , Ali ME , Latif MA , Fakruzzaman M
Published: October 2023

Artificial insemination (AI) is modern techniques to introduce better and new genetic at the small holder farmer level by using frozen for livestock development. The aimed of the present study to popularization of goat’s artificial insemination to increase goat production with improved genetic merit by assessing the productive and reproductive traits using Jamunapari frozen semen.  The study has been conducted in ten upazila namely Paba, Bagha, Nachal, Chapai sador under Rajshahi region and Birampur, Parbotipur, Fulbari, Kaliganj, Ulipur, Kawnia upazilas under the Rangpur regions. Artificial insemination has been performed in 260 numbers of does. The semen samples initially qualified for freezing was frozen as per the protocol standardized in BRAC bull station, stored in liquid nitrogen (LN2) having the post thaw motility of 50% and were later used for AI. The service per conception was 1.10 in the present study. Moreover, we found that overall conception rate was 67.1%. The average birth weight of male and female kids was 0.98 and 0.95 kg, respectively. In the present study kidding produced single, twins and triplets in 37.7, 50.65 and 11.69% of cases, respectively. The average post-partum heat period was 76.5 days. The results indicated frozen semen AI could successfully be used for preservation, conservation and propagation in Jamunapari goats.
Bangladesh Journal of Animal Science 52 (3): 85-87.
Diversity of upper respiratory tract pathogens in patients having flu-like symptoms during Covid-19 pandemic in a referral hospital
Authors: Rahman Md Mizanur , Ayaz KFM , Islam Sadiqul , Hasan Nazmul , Rahim Rummana , Hasan Abu
Published: October 2023

Background: Upper respiratory tract infections (URTIs) are caused by a wide range of viruses and bacteria, however, produce similar symptoms. Routine molecular tests are not performed and empirical use of antibiotics in treating URTIs is a major public health concern. In attempt to unveil the diversity of upper respiratory tract pathogens in the community during COVID-19 pandemic, we have screened 153 nasopharyngeal swab samples from patients having flu like symptoms.
Materials and methods: We tested nasopharyngeal swabs by real-time multiplex PCR for 19 viruses and 3 bacteria using cartridge based rapid PCR platform.
Results: Of 153 patients sample tested, 103 (67.32%) had a laboratory-confirmed respiratory pathogen. Of the 153 swabs tested rhinovirus/enterovirus was found 25(16.34%), influenza 18(11.77%), RSV 13(8.5%), SARS-CoV2- 15(11.11%), other coronaviruses 11(7.19%), parainfluenza 16(10.45%), human metapneumovirus 8(5.23%). Out of 18 influenza cases influenza A was 17(11.12%) and influenza B was 1(0.65%). Among 17 influenza A viruses H1N1pdm09 strain was 9(5.88%), H3 was 5(3.27%). These data shows that even in COVID-19 pandemic period rhinovirus/ enterovirus and Influenza dominated over all other respiratory viruses and as a causative agent bacteria might play very insignificant role in URTIs.
Conclusion: Our data provides strong evidence against empiric antibiotic use for treating URTIs and highlights a strong need for improving the diagnostic capacity for URTIs by using more molecular testing in the country.

J Bangladesh Coll Phys Surg 2023; 41(4): 256-261
Analisa Penerapan K3 dengan Metode FMEA dan FTA pada PT. Sumber Alam Santoso Pratama Banyuwangi
Authors: Prisilia Harliwanti , Purnomo Dimas Aji
Published: October 2023

Dalam dunia bisnis industri sekarang Keselamatan dan Kesehatan Kerja (K3) sangat diperlukan. Namun pada kenyataannya ada banyak hal yang menghambat proses produksi dikarenakan adanya kecelakaan kerja. Karena pada sebuah perusahaan produksi memiliki target waktu pengerjaan yang harus cepat diselesaikan. Salah satunya kecelakaan kerja terjadi di PT. Sumber Alam Santoso Pratama. Tujuan penelitian ini yaitu untuk menganalisa penyebab kecelakaan kerja dan mengetahui tingkat produktivitas kerjanya. Metode yang dipakai adalah FMEA dan FTA. Hasil Penelitian berdasarkan metode FMEA adalah perhitungan RPN tertinggi yaitu pada kegiatan terkena mesin dengan nilai 37,5. Sedangkan hasil dari metode FTA adalah tingkat produktivitasnya dalam kurun waktu 3 tahun, yaitu 0,998, 0,997 dan 0,996. Setelah itu dilakukan analisa penggunakan pohon faktor kegagalan didapatkan hasil bahwa adanya kelalaian dari karyawan terhadap pentingnya menggunakan alat perlindungan diri (APD) dan manajemen pabrik yang kurang memberikan sosialisasi mengenai pentingnya keselamatan kerja.
Analysis of Online Learning Applications During The Covid-19 Pandemic
Authors: Huda Syafaat Ariful , Jaenudin Jaenudin , Muqtashid Amry , Widiatna Alexius Dwi , Nababan Holong Saor
Published: October 2023

This study aims to analyze the perceptions of English language education students towards applications that are used effectively and the most effective applications for online learning in the era of the Covid-19 pandemic. This research uses the SEM (Structural Equation Modeling) method. The subjects of this study were 105 sixth-semester students of English Language Education at UIN Sultan Maulana Hasanudin Banten. The instrument used in this study was a questionnaire. Analyze data using descriptive statistics and structural equation modeling in inferential statistics. The findings showed that students had a positive or positive perception of effective applications for online learning during the Covid-19 pandemic. Based on the findings, it can be seen that the application used by students in online learning in this pandemic era is very effective because the distance learning process has become easier with the application. Then 77% of respondents said that the most efficient application used in online learning is Google Meet because, technically, Google Meet is easier to use, does not require much internet costs, does not interfere when online learning, and is convenient to use.
Hybrid Retroauricular Approach Without Ear Canal Skin Incision
Authors: Kim Soon Joon , Kwon Joong Keun
Published: October 2023

The majority of tympanoplasty procedures have been performed using the retroauricular approach to improve visualisation of the anterior tympanic membrane. The classic retroauricular approach requires elevation of the Körner flap and tympano-meatal flap through the ear canal skin incision. This step can lead to the exposure of the bones in the ear canal, resulting in delayed wound healing and pain, especially in elderly or immunocompromised patients. Endoscopic ear surgery is a minimally invasive procedure that offers a wider field of view, but has the disadvantage of being a one-handed operation and cannot avoid skin incisions in the ear canal for tympanoplasty. Here we present a hybrid retroauricular approach without skin incision of the ear canal, using both microscope and endoscope. This method provides very fast wound healing and significantly less pain.
MEMBANGKITKAN BISNIS UMKM MELALUI PENTA HELIX SEBAGAI EKONOMI PROGRESIF
Authors: Karina Utami Anastuti  , Rio Era Deka
Published: October 2023

Tujuan dari penelitian ini adalah untuk mengetahui dan  mengembangkan potensi UMKM terpadu berbasis wilayah, peningkatan kemampuan digital UMKM, replikasi kemitraan strategis UMK dan UMK, serta pengembangan ruang produksi bersama bagi sentra UMKM. Dengan tujuan ekonomi progresif berupaya untuk mempengaruhi pasar melalui kebijakan atau aturan main yang mampu meningkatkan kesejahteraan kaum miskin dan mengurangi ketimpangan pendapatan dan kesejahteraan masyarakat. Konsep Penta Helix merupakan evolusi dari konsep Triple Helix dengan mengintegrasikan peran akademisi, pengusaha, pemerintah dan masyarakat  dalam kegiatan kreatif dan pengetahuan. Melalui kerjasama Penta Helix, pemerintah daerah dapat memberikan tanggungjawab pemberdayaan komunitas atau masyarakat kepada perguruan tinggi sehingga sumberdaya yang dimiliki dapat dipergunakan dengan lebih optimal.
Kata Kunci:  UMKM, Penta Helix, Ekonomi Progresif
 
The purpose of this research is to identify and develop the potential of regional-based integrated MSMEs, increase digital capabilities of MSMEs, replicate MSEs and MSEs strategic partnerships, and develop joint production spaces for MSME centers. With the goal of a progressive economy trying to influence the market through policies or rules of the game that are able to increase the welfare of the poor and reduce income inequality and social welfare. The Penta Helix concept is an evolution of the Triple Helix concept by integrating the roles of academics, entrepreneurs, government and society in creative and knowledge activities. Through the Penta Helix collaboration, local governments can give community or community empowerment responsibilities to universities so that their resources can be used more optimally.
Keywords:  SMEs, Penta Helix, Progressive Economy
WHEN THE INFLUENCE OF BRAND LOVE ON BUYING SATISFACTION AND INTENTION
Authors: Fariz Nur , Kustiawan Unggul
Published: October 2023

This study seeks to examine the influence of brand love formed by brand experience and brand trust on e-satisfaction and see the possibility of customers to return to using online services, especially in the field of food products. This survey were selected using purposive sampling in Jabota (an acronym of Jakarta – Bogor – Tangerang)  with the sampling criteria of  this study is online food delivery customers, was conducted in October - November 2020 with interviews using questionnairesusers, using a survey with online questionnaires. Data analysis used factor analysis and Lisrel-structural equation modeling (SEM). The findings of this study are hypotheses that support, among others, brand experience contributes to brand love, then brand love shows positive results that affect e-satisfaction, and brand love also has a positive effect with re-purchase intentions. This resaurce interpreted while brand trust does not have a positive effect on brand love, brand experience does not show positive results on re-purchase intention and e-satisfaction also does not contribute positively to re-purchase intention. This study interprets the brand factors that influence e-purchase intentions as influenced by brand love, e satisfaction, brand experience and brand trust. This study seeks to explore whether they influence customers to be able to e-purchase.
PENGARUH GAYA KEPEMIMPINAN, KOMUNIKASI EFEKTIF DAN PENGAMBILAN KEPUTUSAN TERHADAP KINERJA KARYAWAN PT WIWA COMPANY DI KOTA SOLO
Authors: Wiwa Riga Asa , Syaflan Meidi , Ambarwati Lilik
Published: October 2023

Tujuan penelitian ini adalah untuk mengetahui bagaimana gaya kepemimpinan, komunikasi efektif, dan pengambilan keputusan secara parsial mempengaruhi kinerja pekerja. Hal ini juga berupaya untuk memastikan bagaimana faktor-faktor ini berhubungan dengan kinerja pekerja jika digabungkan. Memanfaatkan penelitian deskriptif adalah metodologi penelitiannya. Masing-masing dari 45 karyawan PT. Perusahaan Wiwa yang dijadikan objek penelitian dalam penelitian ini yang meliputi seluruh karyawan perusahaan tersebut. Sebagai bagian dari penelitian ini, kuesioner digunakan untuk mengumpulkan data. Metode analisis regresi berganda diterapkan dalam penelitian ini. Temuan dari penelitian ini menunjukkan bahwa gaya seorang pemimpin tidak berpengaruh secara signifikan dan positif terhadap kinerja tenaga kerjanya. Dampak komunikasi yang efisien terhadap kinerja pekerja bersifat positif dan substansial. Tindakan pengambilan keputusan mempunyai dampak yang penting dan menguntungkan terhadap kinerja karyawan. Gaya seorang pemimpin, komunikasi yang baik, dan pengambilan keputusan secara bersamaan semuanya berdampak positif dan signifikan terhadap kinerja anggota timnya.
 
The aim of this research is to find out how leadership style, effective communication and decision making partially influence worker performance. It also seeks to ascertain how these factors relate to worker performance when combined. Utilizing descriptive research is the research methodology. Each of the 45 employees of PT. The Wiwa company which was used as the research object in this study included all employees of the company. As part of this research, questionnaires were used to collect data. The multiple regression analysis method was applied in this research. The findings of this research indicate that a leader's style does not have a significant and positive effect on the performance of his workforce. The impact of efficient communication on employee performance is positive and substantial. Decision-making actions have an important and beneficial impact on employee performance. A leader's style, good communication, and simultaneous decision making all have a positive and significant impact on the performance of their team members.
The Diagnostic Significance of C3d Antigen in Kidney and Skin Histopathology – The Current State-Of-The-Art and Practical Examples
Authors: HREŠKO S , MAĎAROVÁ M , DOBOŠOVÁ M , PALUŠEKOVÁ N , NIZNEROVÁ P , ŽIARAN S , VARGA I
Published: October 2023

The aim of this narrative review is to summarize recent knowledge about the diagnostic significance of immunobiological detection of C3d with a focus on renal and skin tissue biopsies. We completed the present narrative review with our own experiences with preparation and practical use of monoclonal C3d antibodies at a small national level.
Decellularization techniques of human foreskin for tissue engineering application
Authors: Novotna O , Varchulova Novakova Z , Galfiova P , Lorencova M , Klein M , Žiaran S , Kuniakova M
Published: October 2023

The rapid development of tissue engineering (TE) and regenerative medicine brings an acute need for biocompatible and bioactive biological scaffolds to regenerate or restore damaged tissue. Great attention is focused on the decellularization of tissues or even whole organs, and the subsequent colonization of such decellularized extracellular matrices by recipient cells. The foreskin is an integral, normal part of the external genitalia that forms the anatomical covering of the glans penis and the urinary meatus of all human and non-human primates. It is mucocutaneous tissue that marks the boundary between mucosa and skin. In this work, we compared two innovative decellularization techniques for human foreskins obtained from donors. We compared the efficacy and feasibility of these protocols and the biosafety of prepared acellular dermal matrixes that can serve as a suitable scaffold for TE. The present study confirms the feasibility of foreskin decellularization based on enzymatic or detergent methods. Both techniques conserved the ultrastructure and composition of natural ECM while being DNA-free and non-toxic, making it an excellent scaffold for follow-up research and TE applications.
Chrono-nutrition and its Association with Chronotype and Blood Glucose Control Among People with Type 2 Diabetes
Authors: S. Suneeta , Mehta Nupur S. , Neelam M. Rathod Neelam M. Rathod
Published: October 2023

Background: Recent studies have revealed conflicting results for low glycaemic index (GI) meals in the prevention and treatment of metabolic disorders. Diurnal variations in glucose homeostasis, which are frequently overlooked in epidemiological studies, may help to explain some of these discrepancies.

Food is an external cue to entrain the circadian rhythm, and meal timing is a crucial factor for glucose homeostasis. The study examines the relationship between chrono-nutrition, chronotype, and blood glucose control among people with Type 2 diabetes.

Materials and Methods: Chrono-nutrition questionnaire assessed eating window, breakfast skipping, evening latency, evening eating, night eating, and largest meal of patients with Type 2 diabetes. Glycaemic control was assessed using a HbA1c test, fasting blood sugar, and 2-hour post-prandial blood sugar test. Insulin resistance was assessed by fasting triglyceride glucose index (TyG).

Results: There was a significant association between late dining with dysglycaemia, irrespective of GI of the meal (p<0.05). Participants who had the largest meal during the active phase had better glycaemic control (p<0.05).

Shorter eating windows and evening latency of at least 2 hours not only aided in glycaemic control, but also gave good sleep (p<0.05). Participants with the evening chronotype ate almost twice the amount of carbohydrates and fat at dinner than at breakfast. Evening chronotypes were associated with lesser servings of vegetables and fruits, and greater servings of sweets and caffeinated beverages, in comparison with morning chronotypes.

Conclusions: Late diners had significantly worse blood glucose levels, irrespective of the GI of the meal. This may have public health implications, as calorie-dense meals are often consumed during late evenings, which can desynchronise the circadian rhythms. Eating meals as per the circadian rhythm could be an alternative non-pharmacological strategy to prevent diabetes and its complications.
TAHKİME ELVERİŞLİLİĞİN İTİRAZ ÜZERİNE İNCELENMESİNE İLİŞKİN BAZI DEĞERLENDİRMELER (HMK m. 422/1)
Authors: HENDEM Burcu
Published: October 2023

Tahkim, taraflar arasında çıkan uyuşmazlıkların çözülmesi için yaygın olarak başvurulan bir yoldur. Ancak her uyuşmazlık tahkim yoluyla çözülememekte, sadece tahkime elverişli olan uyuşmazlıklar hakkında bu yol mümkün olmaktadır. Ancak tahkime elverişli olmayan bir uyuşmazlıkla ilgili tahkimde dava açıldığında hakemler, bunu re’sen gözetebilecekler midir? Bu soruyla ilgili olarak, 6100 sayılı Hukuk Muhakemeleri Kanunu’nun (HMK) 422. maddesinin 1. fıkrasında hakemlerin, kendi yetkileri hakkında karar verebilecekleri düzenlenmiştir. Bu düzenlemede, itiraz üzerine hakemlerin, kendi yetkileri hakkında karar verebilecekleri ifade edilmiştir. Fakat bu durum, tarafların elverişsizliğe itiraz etmemeleri ihtimalinde sorun yaratabilmektedir. Şöyle ki hakem kararları, mahkeme kararları gibi kesin hüküm teşkil edip ilamlı icranın konusunu oluşturduğu için tahkime elverişli olmayan bir uyuşmazlıkla ilgili verilen hakem kararları da mahkeme kararları gibi kesin hüküm teşkil edip icra edilebilecektir. Bu nedenle bu çalışmada, önce tahkime elverişliliğin tanımı, türleri ve elverişlilikle ilgili Türk hukukundaki düzenlemelere yer verildikten sonra, HMK’nın 422/1 hükmü çerçevesinde hakemler tarafından tahkime elverişliliğin incelenmesi ve çıkabilecek sorunlar üzerinde durulacaktır.
Comparison and Gender Injustice in Worlds of Pandemics
Authors: Thornber Karen
Published: October 2023

With several notable exceptions, comparative literature scholarship has not fully addressed the relationships between literature and global challenges and crises. In our era of multiple intensifying pandemics, not to mention often anaemic humanities enrolments (paradoxical, given robust interest in the arts both within and outside academia), it is crucial that comparative literature go more global: engaging more deeply with a broader array of texts, pathways and processes than ever before with a focus on providing insights into global challenges and crises as well as possibilities for amelioration on a vast scale. This article focuses on three novels: He Jiahong’s Chinese-language Hanging Devils: Hong Jun Investigates (1994) from China; Oh Jung-hee’s Korean-language The Bird (1996) from Korea; and Bina Shah’s English-language Before She Sleeps (2018) from Pakistan. These narratives highlight intersections in different parts of Asia among gender inequities/gender-based violence and corruption in criminal justice, intergenerational trauma and environmental catastrophe, respectively. To be sure, scholarship on literature is unlikely to provide immediate remedies. Yet, by helping readers better understand how literature engages with global challenges, scholarship on literature, including the field of comparative literature, can contribute to increasing motivations and the ability to take the essential leap to become champions for change.
Üniversite Öğrencilerinin Mobil Öğrenme Tutumları ile Öz Yönetimli Öğrenme Becerileri Arasındaki İlişkinin İncelenmesi
Authors: Çıtak Şenel , Akman Emrah
Published: October 2023

Bu araştırmanın amacı üniversite öğrencilerinin mobil öğrenme tutumları ile öz yönetimli öğrenme becerileri arasındaki ilişkili incelemektir. İlişkisel tarama modeli kullanılarak yürütülen araştırmaya Türkiye’nin farklı şehirlerindeki üniversitelerde öğrenim gören 317 kadın, 103 erkek olmak üzere toplam 420 üniversite öğrencisi katılmıştır. Araştırmanın verileri demografik bilgi formu, mobil öğrenme tutum ölçeği ve öz yönetimli öğrenme ölçeği ile toplanmıştır. Sonuç olarak; üniversite öğrencilerinin mobil öğrenme tutum puanı ve öz yönetimli öğrenme düzeyi cinsiyete göre farklılık göstermemiştir. Ayrıca üniversite öğrencilerinin mobil öğrenme tutumu ile öz yönetimli öğrenme düzeyi arasında pozitif yönde anlamlı bir ilişki olduğu saptanmıştır. Araştırma bulgularından hareketle; üniversite öğrencilerinin mobil öğrenmeye yönelik tutumlarını ve öz yönetimli öğrenme düzeylerini etkileyen diğer faktörlerin, öz yönetimli öğrenme düzeyinin ilişkili olabileceği farklı değişkenlerin saptanması ve bu değişkenlerin mobil öğrenme tutumu ve öz yönetimle öğrenme gibi değişkenlerle karşılaştırıldığı yeni çalışmalar yapılması önerilmiştir.
Factual belief polarization between Democrats and Republicans: Source or epiphenomenon of ideological and affective polarization?
Authors: Rekker Roderik
Published: October 2023

Democrats and Republicans have polarized in their attitudes and their feelings toward each other. Simultaneously, both groups also diverge in their factual perceptions of reality. This experiment examined how this factual belief polarization may or may not fuel ideological and affective polarization around income differences, immigration, climate change, and defense spending. Democrats and Republicans were equally or more divided in their beliefs about the present than in their ideals for the future. Corrective information decreased polarization over some ideals, but not policy attitudes. Priming perceptions conversely increased polarization around defense spending, but not other issues. Much remains unclear about the complex relation between factual beliefs and polarization, but measuring ideals and priming beliefs could be promising avenues for future research.
Microwave cooking of thin potato discs
Authors: Budd OBE Chris J. , Piva Paulo S. , Shirley Matthew D. , Whittaker Robert J.
Published: October 2023

We consider the cooking of thin potato slices in a microwave oven. It has been observed that this cooking method leads to under-cooking at the edges of the disc. For a uni-modal field the under-cooking occurs on the edge tangential to the direction of the applied field, while for a multi-modal field, the under-cooking occurs around the entire circumference. We develop a mathematical model for the electric field in both these situations, modelling the electric field using the Helmholtz equations. Using asymptotic analysis, we exploit the small aspect ratio and large dielectric constant in the disc, and are able to predict cooking patterns consistent with experimental observations in both cases. We also consider a simplified 2D electrostatic model, in order to explore the possible asymptotic structure of the solution in more detail.
EKSPOSUR KOMUNIKASI POLITIK JOKO WIDODO TERHADAP GENERASI MILENIAL PADA PEMILIHAN UMUM
Authors: Suprayitno Dede
Published: October 2023

Abstrak. Generasi milenial memiliki suara menentukan dalam pemilihan umum. Pada 2019, daftar pemilih tetap (DPT) mencapai 196,5 juta orang yang berhak memberikan suara. Pada tahun itu, pemilih milenial atau muda mencapai 100 juta orang, dengan rentang usi 17-35 tahun. Secara matematis, suara milenial memiliki pengaruh yang signifikan. Tak heran bila akhirnya, para elit politik mengatur strategi agar meraih suara milenial. Salah satu diantaranya adalah Presiden Joko Widodo yang memahami hal tersebut dan melakukan eksposur yang khas pada kalangan milenial. Sebagai seorang politikus, Joko Widodo menerapkan segala potensi yang dimilikinya untuk meraih dukungan sebanyak-banyaknya. Penelitian ini untuk mengungkap seperti apa langkah Joko Widodo dalam membentuk kedekatan dengan generasi muda. Serta aktivitas dan simbol-simbol apa saja yang ditunjukkan oleh Joko Widodo. Penelitian ini menggunakan pendekatan kualitatif bersifat eksplanatori. Data dan informasi yang didapat melalui studi kepustakaan. Hasil penelitian menunjukkan aktivitas Joko Widodo sebagai bentuk komunikasi kepada publik, bersifat unik, berbeda dari politikus lainnya, dan mendobrak kebiasaan umum. Joko Widodo juga identik dengan anak muda dengan selera yang dipilihnya, seperti musik, film dan olahraga. Hal itu membuat Joko Widodo dekat secara emosional dengan anak muda. Penelitian ini juga menyimpulkan, bahwa perang gagasan serta kreativitas di media sosial menentukan hasil keseluruhan dari persaingan politik.
Inhibition of urethral stricture by a catheter loaded with nanoparticle/ pirfenidone complexes
Authors: Meng Wei , Jiang Zhaosheng , Wang Jiahao , Chen Xiaohua , Chen Bo , Cai Bo , Zhou Youlang , Ma Limin , Guan Yangbo
Published: October 2023

Background: Urethral strictures are common injurious conditions of the urinary system. Reducing and preventing urethral strictures has become a hot and challenging topic for urological surgeons and related researchers. In this study, we developed a catheter loaded with nanoparticle/pirfenidone (NP/PFD) complexes and evaluated its effectiveness at inhibiting urethral stricture in rabbits, providing more references for the clinical prevention and reduction of urethral stenosis.

Methods: Twelve adult male New Zealand rabbits were selected and divided into the following four groups in a ratio of 1:1:1:1 using the random number table method: Group A, sham; Group B, urethral stricture (US); Group C, US + unmodified catheter; and Group D, US + NP/PFD catheter. On the 30th day after modelling, retrograde urethrography was performed to evaluate urethral stricture formation, and histopathological examination was performed on the tissues of the corresponding surgical site. Meanwhile, changes in the expression level of Transforming growth factor β1 (TGF-β1) in the tissues were detected by immunohistochemistry.

Results: The NP/PFD complexes adhered uniformly to the catheter surface. They remained on the surface of the catheter after insertion into the urethra. In addition, the NP/PFD complexes spread into the urethral epithelium 2 weeks after surgery. Ultimately, urethral strictures were significantly reduced with the placement of the NP/PFD complex catheter.

Conclusion: Our catheter loaded with NP/PFD complexes effectively delivered PFD to the urethral epithelium through continuous local delivery, thereby reducing fibrosis and stricture after urethral injury, which may be associated with the inhibition of TGF-β1 expression.
Electric field bridging-effect in electrified microfibrils’ scaffolds
Authors: Fontana Sara , Caramazza Laura , Marracino Paolo , Cuenca Ortolá Irene , Colella Micol , Dolciotti Noemi , Paffi Alessandra , Gisbert Roca Fernando , Ivashchenko Sergiy , Más Estellés Jorge , Consales Claudia , Balucani Marco , Apollonio Francesca , Liberti Micaela
Published: October 2023

Introduction: The use of biocompatible scaffolds combined with the implantation of neural stem cells, is increasingly being investigated to promote the regeneration of damaged neural tissue, for instance, after a Spinal Cord Injury (SCI). In particular, aligned Polylactic Acid (PLA) microfibrils’ scaffolds are capable of supporting cells, promoting their survival and guiding their differentiation in neural lineage to repair the lesion. Despite its biocompatible nature, PLA is an electrically insulating material and thus it could be detrimental for increasingly common scaffolds’ electric functionalization, aimed at accelerating the cellular processes. In this context, the European RISEUP project aims to combine high intense microseconds pulses and DC stimulation with neurogenesis, supported by a PLA microfibrils’ scaffold.

Methods: In this paper a numerical study on the effect of microfibrils’ scaffolds on the E-field distribution, in planar interdigitated electrodes, is presented. Realistic microfibrils’ 3D CAD models have been built to carry out a numerical dosimetry study, through Comsol Multiphysics software.

Results: Under a voltage of 10 V, microfibrils redistribute the E-field values focalizing the field streamlines in the spaces between the fibers, allowing the field to pass and reach maximum values up to 100 kV/m and values comparable with the bare electrodes’ device (without fibers).

Discussion: Globally the median E-field inside the scaffolded electrodes is the 90% of the nominal field, allowing an adequate cells’ exposure.
Macrophage polarization in osteoarthritis progression: a promising therapeutic target
Authors: Zhang Yanlei , Ji Quanbo
Published: October 2023

Osteoarthritis (OA) is one of the leading causes of pain and disability in the elderly. Synovitis, cartilage destruction and osteophyte formation histologically manifest OA. Unfortunately, there is currently no effective therapy to delay its progression and the underlying mechanisms of OA require further exploration. Macrophage is a main cellular component of joint synovium. It is highly plastic and can be stimulated to polarize to different phenotypes, namely, the pro-inflammatory phenotype (M1) and the anti-inflammatory/tissue-repairing phenotype (M2). Ample evidence has demonstrated the vital roles of macrophages in the progression of OA. Imbalanced M1/M2 ratio is significantly related to OA severity indicating macrophage polarization might be a promising therapeutic target for OA. In this review, we summarized the involvements of polarized macrophages in synovitis, cartilage degradation, osteophyte formation and OA-related chronic pain. Promising therapies targeting macrophage polarization including the intra-articular cell/derivates-based therapy and the alternative non-invasive intervention such as photobiomodulation therapy were reviewed as well.
Methanol extract of Iraqi Kurdistan Region Daphne mucronata as a potent source of antioxidant, antimicrobial, and anticancer agents for the synthesis of novel and bioactive polyvinylpyrrolidone nanofibers
Authors: Muzammil Khursheed , Kzar Mazin Hadi , Mohammed Faraj , Mohammed Zahraa Ibrahim , Hamood Sarah A. , Hussein Talib Kh. , Hanoon Saheb Jubeir , Qasim Maytham T. , Hussien Alawadi Ahmed , Alsalamy Ali
Published: October 2023

In this study, aqueous, ethanol, methanol, and hexane extracts from Iraqi Kurdistan Region Daphne mucronata were prepared due to the numerous applications and development of nanofibers in biological and medical fields, including food packaging, enzyme stabilization, and wound dressing. In the initial evaluation of the extracts, the antioxidant properties against DPPH, antimicrobial properties against 3-gram-positive bacterial species, 3-gram negative bacterial species, 3-common bacterial species between aquatic and human, and 3-fungal species, and anticancer properties against breast cancer cells were performed. The results proved that the methanol extract has the highest antimicrobial, antifungal, antioxidant, and anticancer properties. After identifying the compounds of prepared methanol extract using GC/MS, polyvinylpyrrolidone nanofibers containing methanol extract of Daphne mucronata were prepared. The structure and characteristics of prepared nanofibers were confirmed and determined using FTIR, TGA, BET, SEM, flexural strength, compressive strength, and hydrophilicity. Synthesized polyvinylpyrrolidone nanofibers containing methanol extract of D. mucronata were subjected to antimicrobial properties on the strains studied in methanol extract of D. mucronata. The antimicrobial properties of synthesized polyvinylpyrrolidone nanofibers containing methanol extract of D. mucronata were compared. The results showed that synthesized polyvinylpyrrolidone nanofibers containing methanol extract of D. mucronata have the potential to introduction bioactive natural synthesis nanoparticles.
Training community engaged climate adaptation leaders using multiple case study analysis: insights from cognitive learning sciences
Authors: Abercrombie Sara , Stuart Diana Lynne , Aslan Clare Ellsworth , Souther Sara , Petersen Brian Craig
Published: October 2023

Training community engaged climate adaptation leaders requires developing learners' thinking skills so they can flexibly approach adaptation planning and problem solving in novel socio-ecological contexts. In this text, we describe how multiple case study analysis helps adult learners in both formal and community education settings develop the thinking skills necessary for adaptation work, including analogical reasoning and knowledge transfer; and we illustrate how to organize multiple case analysis on shared critical competencies aligned to community needs. The article concludes with a discussion of three instructional best practices for employing multiple case analysis in educational settings and a discussion of how this educational approach can guide training programs and funding priorities.