bluuebunny/crossref_metadata_2025 huggingface dataset:
Conservation and Divergence of the CONSTANS-Like (COL) Genes Related to Flowering and Circadian Rhythm in Brassica napus
Authors: Chen Yuxi , Zhou Rijin , Hu Qiong , Wei Wenliang , Liu Jia
Published: November 2021

The CONSTANS-LIKE (COL) genes are important signaling component in the photoperiod pathway and flowering regulation pathway. However, people still know little about their role in Brassica napus. To achieve a better understanding of the members of the BnaCOL gene family, reveal their evolutionary relationship and related functions involved in photoperiod regulation, we systematically analyzed the BnaCOL family members in B. napus genome. A total of 33 BnaCOL genes distributed unevenly on 16 chromosomes were identified in B. napus and could be classified into three subfamilies. The same subfamilies have relatively conservative gene structures, three-dimensional protein structures and promoter motifs such as light-responsive cis-elements. The collinearity analysis detected 37 pairs of repetitive genes in B. napus genome. A 67.7% of the BnaCOL genes were lost after B. napus genome polyploidization. In addition, the BnaCOL genes showed different tissue-specific expression patterns. A 81.8% of the BnaCOL genes were mainly expressed in leaves, indicating that they may play a conservative role in leaves. Subsequently, we tested the circadian expression profiles of nine homologous genes that regulate flowering in Arabidopsis. Most BnaCOL genes exhibit several types of circadian rhythms, indicating that these BnaCOL genes are involved in the photoperiod pathway. As such, our research has laid the foundation for understanding the exact role of the BnaCOL family in the growth and development of rapeseed, especially in flowering.
Authentic Expertise: Andrej Babiš and the Technocratic Populist Performance During the COVID-19 Crisis
Authors: Hartikainen Ilana
Published: November 2021

This article studies how a technocratic populist can visually perform the authenticity and connection to ‘the low’ that is key to a populist performance while also maintaining the performance of expertise that is central to technocratic populist success. It relies on the case study of Czech prime minister Andrej Babiš and uses Facebook data from his profile in March and September–October 2020, the two peak moments of the crisis in the first and second waves of the COVID-19 pandemic. After offering a timeline of the Czech COVID-19 epidemic in 2020, it applies a dramaturgical analysis to four representative photos from Babiš’ Facebook page. It finds that Babiš was able to simultaneously articulate both expertise and authenticity, thereby both creating a connection to ‘the people’ while also articulating himself as an expert capable of handling the pandemic. He articulated expertise through a technocratic bodily performance, presenting himself as a cosmopolitan leader with international symbols of power like neutral-colored suits and elegant surroundings. At the same time, he also articulated himself as an authentic politician by showing his Facebook followers backstage imagery like a disorganized table and by showing himself as a busy man and an exceptionally hard worker. By illuminating the visual performance of technocratic populism, it offers insight into how technocratic populists constitute the expertise that their success rests on and that can also pose a threat to democratic societies, especially in a time of crisis.
The General Factor of Personality as Ego-Resiliency
Authors: Dunkel Curtis S. , van der Linden Dimitri , Kawamoto Tetsuya , Oshio Atsushi
Published: November 2021

It was originally hypothesized by Block that what has come to be known as the General Factor of Personality (GFP) reflects ego-resiliency. We test Block’s hypothesis in two studies. In Study 1 a meta-analysis (N = 15,609) examining the relationship between the GFP and ego-resiliency/resilience was conducted. In Study 2 (N = 157) archival data from Block and Block was used to examine the association between rater judged ego-resiliency across childhood, adolescence, and into early adulthood and the GFP based on self-report in early adulthood. Using structural equation modeling for the meta-analytic data, the correlation between the GFP and ego-resiliency/resilience was estimated at r = 0.93. Using a trait-state occasion model to test the hypothesis in Study 2, the correlation between the GFP and rated ego-resiliency was estimated at r = 0.85. The results of the two studies offer substantial support for Block’s original hypothesis. Given the strength of the associations between the GFP and ego-resiliency/resilience one may conclude that the two constructs largely reflect the same underlying phenomenon.
Can Viewing Nature Through Windows Improve Isolated Living? A Pathway Analysis on Chinese Male Prisoners During the COVID-19 Epidemic
Authors: Li Hansen , Zhang Xing , You Chengming , Chen Xin , Cao Yang , Zhang Guodong
Published: November 2021

Nature exposure is known to promote life satisfaction and well-being, and indirect exposure through windows is likely to benefit isolated populations. However, whether such type of exposure can benefit prisoners, the extremely isolated population, is unknown. In the current study, we investigated 326 male prisoners from three prisons in southwest China. Psychological variables including depression, anxiety, loneliness, distress tolerance, life satisfaction, and well-being were measured using the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), short-form UCLA Loneliness Scale (ULS-6), Distress Tolerance Scale (DTS), Satisfaction with Life Scale (SWLS), and 5-item World Health Organization Well-Being Index (WHO-5), respectively. Structural equation modeling was employed to identify the pathways from the visibility of nature through windows to prisoners' life satisfaction and well-being. Our results demonstrated that visibility of nature promoted the frequency and duration of viewing nature through windows. The frequency directly affected well-being, but the duration did not effectively affect any measured variables. The visibility of nature enhanced life satisfaction mainly via direct effects but enhanced well-being mainly via indirect effects. Regarding the indirect pathways, the visibility of nature increased distress tolerance and thus reduced loneliness and mental health problems. The reduced mental health problem, in turn, promoted life satisfaction and well-being. Our findings suggest that nature exposure through windows is effective in enhancing prisoners' life satisfaction and well-being. The policymaker may need to consider nature-based solutions such as indirect nature exposure in prions to benefit isolated populations.
Recovery Education for Adults Transitioning From Homelessness: A Longitudinal Outcome Evaluation
Authors: Durbin Anna , Nisenbaum Rosane , Wang Ri , Hwang Stephen W. , Kozloff Nicole , Stergiopoulos Vicky
Published: November 2021

Objective: Grounded in principles of adult education, Recovery Education Centres (RECs) hold promise in promoting recovery for adults with mental health challenges, but research on recovery outcomes for hard-to-reach populations participating in RECs is scant. This quasi-experimental study compares 12-month recovery outcomes of adults with histories of homelessness and mental health challenges enrolled in a REC, to those of participants of other community services for this population.

Methods: This pre-post quasi-experimental study compared participants enrolled in a REC for people with histories of homelessness and mental health challenges (n = 92) to an age-and-gender frequency matched control group participating in usual services (n = 92) for this population in Toronto, Ontario. Changes from program enrollment to 12 months in personal empowerment (primary outcome), disease specific quality of life, recovery, health status, health related quality of life, and mastery were assessed. Post-hoc analyses compared subgroups with 1–13 h (n = 37) and 14+ h (n = 37) of REC participation during the study period to the control group. Linear mixed models estimated mean changes and differences in mean changes and 95% confidence intervals.

Results: Mean change in perceived empowerment from program enrollment to 12 months in the intervention group [0.10 (95% CI: 0.04, 0.15)] was not significantly different from the control group [0.05 (−0.01, 0.11)], mean difference, 0.05 [(−0.03, 0.13), P = 0.25]. In the post-hoc analysis, the mean change in perceived empowerment for the intervention subgroup with 14+ h of REC participation [0.18 (0.10, 0.26)] was significantly different than in the control group [0.05 (−0.01, 0.11)] mean difference, 0.13 [(0.03, 0.23), P < 0.01]. Mean change in mastery was also significantly different for the intervention subgroup with 14+ h of REC participation [2.03 (1.04, 3.02)] vs. controls [0.60 (−0.15, 1.35)], mean difference, 1.43 [(0.19, 2.66), P = 0.02]. There were no significant differences in other outcomes.

Conclusion: With sufficient hours of participation, recovery education may be a helpful adjunct to health and social services for adults with mental health challenges transitioning from homelessness.
Influence of Clinical Markers of Dopaminergic Behaviors on Depressive Symptoms During Withdrawal in Cocaine Users
Authors: Cabé Julien , Brousse Georges , Pereira Bruno , Cabé Nicolas , Karsinti Emily , Zerdazi El-Hadi , Icick Romain , Llorca Pierre M. , Bloch Vanessa , Vorspan Florence , De Chazeron Ingrid
Published: November 2021

Background: During cocaine withdrawal, transient depressive symptoms that do not meet the criteria for depression, but promote relapse, are frequently observed. Their temporality could evoke a role of dopamine, especially since the underlying mechanism of these depressive symptoms is not well understood. We hypothesized that variation in the dopaminergic activity profile, modeled from clinical markers, could be implicated in the development of depressive symptoms during cocaine withdrawal.

Methods: We compared patients reporting depressive symptoms (RDS+) or not (RDS–) during cocaine withdrawal. We evaluated dopaminergic activity through indirect clinical markers based on the known dopaminergic behaviors. A combined criterion was constructed for hyper and hypo dopaminergic models according to the O'Brien method and illustrated by the Hedges' effect-size and forest-plot graph. A multidimensional factorial analysis was carried out to determine which parameters discriminate RDS+/RDS– patients.

Results: 313 patients were included, and 77% reported depressive symptoms during cocaine withdrawal. Hyperdopaminergic variables used to discriminate the two groups had a large overall effect size (−0.669) and included psychotic symptoms (−0.524), hallucinations (−0.548), and delusions (−0.528). The overall effect of the hypodopaminergic component was considerable (−0.604) with a large effect size for the severity of dependence (−0.616), withdrawal symptoms (−0.578), and anhedonia (−0.528). The combined model including hyperdopaminergic and hypodopaminergic components had the largest effect size (−0.785).

Conclusion: The dopaminergic activities profile, assessed by indirect clinical markers, seems to characterize patients with depressive symptoms very well during cocaine withdrawal. RDS+ patients reported moreover higher levels of psychotic symptoms and more severe cocaine use disorder than RDS–.
Robot Responsibility and Moral Community
Authors: Gogoshin Dane Leigh
Published: November 2021

It is almost a foregone conclusion that robots cannot be morally responsible agents, both because they lack traditional features of moral agency like consciousness, intentionality, or empathy and because of the apparent senselessness of holding them accountable. Moreover, although some theorists include them in the moral community as moral patients, on the Strawsonian picture of moral community as requiring moral responsibility, robots are typically excluded from membership. By looking closely at our actual moral responsibility practices, however, I determine that the agency reflected and cultivated by them is limited to the kind of moral agency of which some robots are capable, not the philosophically demanding sort behind the traditional view. Hence, moral rule-abiding robots (if feasible) can be sufficiently morally responsible and thus moral community members, despite certain deficits. Alternative accountability structures could address these deficits, which I argue ought to be in place for those existing moral community members who share these deficits.
The Recycling System in Cells That Helps to Prevent Obesity
Authors: Narro Carla , Rivera Patricia , Morselli Eugenia
Published: November 2021

Our cells have their own recycling center! Autophagy is the name of this amazing process, which allows cells to recycle cellular components to generate new ones and to provide energy for cell survival. If we eat too much high-fat food, autophagy might start malfunctioning in specific parts of the brain, and this can contribute to the development of obesity. Therefore, eating healthy food is important, so we can keep autophagy working properly and prevent obesity!
The Political Ecology of Hedgerows and Their Relationship to Agroecology and Food Sovereignty in the UK
Authors: Tilzey Mark
Published: November 2021

Hedgerows can make an important contribution to agroecological transitions and to an overall contribution to multifunctional agro-ecosystems with multiple benefits for biodiversity, climate change mitigation, soil health, human health, well-being, and livelihoods. Where such agroecological transition assumes the form of political agroecology, this can underpin transformation of the farming system towards food sovereignty. Current mismanagement of hedgerows is constraining the optimum delivery of ecosystem services by these important features of the British landscape. This mismanagement is, moreover, an integral part of a (capitalist) productivist degradation of the countryside that is contributing to the delivery of ecosystem disservices and is, therefore, antithetical to the adoption of agroecological production practises. Being contrary to the requirements of political agroecology, it is similarly antithetical to the requirements of food sovereignty. In response, this paper outlines what appears to be required, in policy and political terms, for the adoption of an agroecological and food sovereignty framework enabling the sustainable management of hedgerows and maximising their potential for ecosystem services delivery.
Comparison of Surgical Outcomes Between Separation Surgery and Piecemeal Spondylectomy for Spinal Metastasis: A Retrospective Analysis
Authors: Xu Lun , Huang Wending , Cai Weiluo , Sun ZhengWang , Fang Meng , Ji Yingzheng , Wang Shuoer , Zhang Jianing , Hu Tu , Cheng Mo , Yan Wangjun
Published: November 2021

Objective: This study aimed to compare the outcomes between piecemeal spondylectomy and separation surgery for patients with spinal metastasis.

Summary of Background Data: Piecemeal spondylectomy and separation surgery are two widely-used treatment options for spinal metastasis. However, no studies have compared the surgical outcomes between both treatment modalities.

Methods: Patients with spinal metastasis who underwent piecemeal spondylectomy or separation surgery between August 2017 and April 2020 at our spine center were recruited. Demographic, preoperative, perioperative, and follow-up data were collected and analyzed. Kaplan–Meier analysis and the log-rank test were used to analyze overall survival (OS) and progression-free survival (PFS) in patients with spinal metastasis.

Results: Overall, 26 patients were treated with piecemeal spondylectomy, and 29 underwent separation surgery with postoperative stereotactic radiosurgery. Both groups showed significant postoperative improvements in neurological status. The piecemeal spondylectomy group had significantly more blood loss (1784.62 ± 833.64 vs. 1165.52 ± 307.38 ml) and required longer operative time (4.76 ± 0.93 vs. 3.73 ± 1.15 h) than the separation surgery group. No significant difference in OS was found between the groups (P = 0.064); however, patients in the separation surgery group experienced less local recurrence than those in the piecemeal spondylectomy group (P = 0.0014). Notably, significant differences were detected in the development of complications between the groups (P = 0.029).

Conclusion: Separation surgery led to less blood loss and reduced complications and had shorter operation time than piecemeal spondylectomy. Although no significant differences were found in OS between the groups, separation surgery was associated with better PFS compared with piecemeal spondylectomy. These findings suggest that separation surgery has some advantages over piecemeal spondylectomy for patients with spinal metastatic disease.
Visualization of Airborne Particles as a Risk for Microbial Contamination in Orthopedic Surgery
Authors: Koseki Hironobu , Sunagawa Shinya , Imai Chieko , Yonekura Akihiko , Matsumura Umi , Yokoo Seiichi , Watanabe Kaho , Nishiyama Yuta , Osaki Makoto
Published: November 2021

Background: The operating theater is recognized to involve a high frequency of occupational blood and body fluid contacts.

Objectives: This study aimed to visualize the production of blood and body fluid airborne particles by surgical procedures and to investigate risks of microbial contamination of the conjunctival membranes of surgical staff during orthopedic operations.

Methods: Two physicians simulated total knee arthroplasty (TKA) and total hip arthroplasty (THA) in a bio-clean theater using model bones. The generation and behaviors of airborne particles were filmed using a fine particle visualization system, and numbers of airborne particles per 2.83 L of air were counted at the height of the operating and instrument tables. Each action was repeated five times, and particle counts were evaluated statistically.

Results: Numerous airborne particles were dispersed to higher and wider areas while “cutting bones in TKA” and “striking and driving the cup component on the pelvic bone in THA” compared to other surgical procedures. The highest particle counts were detected while “cutting bones in TKA” under unidirectional laminar air flow.

Discussion: These results provide a clearer image of the dispersion and distribution of airborne particles and identified higher-risk surgical procedures for microbial contamination of the conjunctival membranes. Surgical staff including surgeons, nurses, anesthesiologists, and visitors, should pay attention to and take measures against occupational infection particularly in high-risk surgical situations.
The Bacterial Community in Questing Ticks From Khao Yai National Park in Thailand
Authors: Takhampunya Ratree , Sakolvaree Jira , Chanarat Nitima , Youngdech Nittayaphon , Phonjatturas Kritsawan , Promsathaporn Sommai , Tippayachai Bousaraporn , Tachavarong Wirunya , Srinoppawan Kanchit , Poole-Smith Betty K. , McCardle P. Wesley , Chaorattanakawee Suwanna
Published: November 2021

Ticks are known vectors for a variety of pathogens including bacteria, viruses, fungi, and parasites. In this study, bacterial communities were investigated in active life stages of three tick genera (Haemaphysalis, Dermacentor, and Amblyomma) collected from Khao Yai National Park in Thailand. Four hundred and thirty-three questing ticks were selected for pathogen detection individually using real-time PCR assays, and 58 of these were subjected to further metagenomics analysis. A total of 62 ticks were found to be infected with pathogenic bacteria, for a 14.3% prevalence rate, with Amblyomma spp. exhibiting the highest infection rate (20.5%), followed by Haemaphysalis spp. (14.5%) and Dermacentor spp. (8.6%). Rickettsia spp. were the most prevalent bacteria (7.9%) found, followed by Ehrlichia spp. (3.2%), and Anaplasma spp. and Borrelia spp. each with a similar prevalence of 1.6%. Co-infection between pathogenic bacteria was only detected in three Haemaphysalis females, and all co-infections were between Rickettsia spp. and Anaplasmataceae (Ehrlichia spp. or Anaplasma spp.), accounting for 4.6% of infected ticks or 0.7% of all examined questing ticks. The prevalence of the Coxiella-like endosymbiont was also investigated. Of ticks tested, 65.8% were positive for the Coxiella-like endosymbiont, with the highest infection rate in nymphs (86.7%), followed by females (83.4%). Among tick genera, Haemaphysalis exhibited the highest prevalence of infection with the Coxiella-like endosymbiont. Ticks harboring the Coxiella-like endosymbiont were more likely to be infected with Ehrlichia spp. or Rickettsia spp. than those without, with statistical significance for Ehrlichia spp. infection in particular (p-values = 0.003 and 0.917 for Ehrlichia spp. and Rickettsia spp., respectively). Profiling the bacterial community in ticks using metagenomics revealed distinct, predominant bacterial taxa in tick genera. Alpha and beta diversities analyses showed that the bacterial community diversity and composition in Haemaphysalis spp. was significantly different from Amblyomma spp. However, when examining bacterial diversity among tick life stages (larva, nymph, and adult) in Haemaphysalis spp., no significant difference among life stages was detected. These results provide valuable information on the bacterial community composition and co-infection rates in questing ticks in Thailand, with implications for animal and human health.
Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism
Authors: Načeradská Martina , Návojová Horáčková Kateřina , Fridrichová Michaela
Published: November 2021

A 6-month-old kitten, male, domestic shorthair cat was presented with dwarfism, ocular and nasal discharge, and Ascaris infestation. Congenital hyposomatotropism was diagnosed on the basis of serum level of insulin-like growth factor-1 (IGF-I). The cat was treated with human recombinant growth hormone for 9 weeks. After that, his liver enzymes became elevated, and the therapy was discontinued. His IGF-I levels were normal at the end of the therapy. Normal IGF-I was present 3 months after discontinuation of therapy with human recombinant growth hormone and even half a year after the discontinuation. All other comorbidities were addressed with the therapy. The cat is now the size of normal cats, living with the first author.
Molecular Epidemiology of Ovine Papillomavirus Infections Among Sheep in Southern Italy
Authors: De Falco Francesca , Cutarelli Anna , D'Alessio Nicola , Cerino Pellegrino , Catoi Cornel , Roperto Sante
Published: November 2021

Ovine papillomaviruses (OaPVs) were detected and quantified, for the first time, using droplet digital polymerase chain reaction (ddPCR) and real-time quantitative PCR (qPCR) via blood samples of 165 clinically healthy sheep. OaPV DNA was detected in 126 blood samples (~76.4%). DdPCR detected OaPV DNA in 124 samples; in only two additional samples positive for real-time qPCR, ddPCR failed to detect the presence of any OaPVs. In 70 of the positive samples (~55.6%), a single OaPV infection was observed, 12 of which were caused by OaPV1 (~17.1%) and 14 by OaPV2 (20%). OaPV3 was responsible for 19 single infections (~27.1%), and OaPV4 for 25 single infections (~35.7%). Multiple OaPV coinfections were observed in 56 (~44.4%) positive samples. OaPV coinfections caused by two genotypes were observed in 31 positive samples (~55.4%), with dual OaPV3/OaPV4 infection being the most prevalent as seen in 11 blood samples. In addition, five OaPV1/OaPV4, four OaPV1/OaPV2, four OaPV2/OaPV3, four OaPV1/OaPV3, and three OaPV2/OaPV4 dual coinfections were also detected. OaPV coinfections by triple and quadruple genotypes were detected in 24 (~42.8%) and only one (~1.8%) of coinfected blood samples, respectively. Multiple infections caused by OaPV1/OaPV3/OaPV4 genotypes were the most prevalent, as observed in 12 (50%) blood samples harboring triple OaPV infections. This study showed that ddPCR is the most sensitive and accurate assay for OaPV detection and quantification thus outperforming real-time qPCR in terms of sensitivity and specificity. Therefore, ddPCR may represent the molecular diagnostic tool of choice, ultimately providing useful insights into OaPV molecular epidemiology and field surveillance.
A Holistic Framework towards Developing a Climate-Smart Agri-Food System in the Middle East and North Africa: A Regional Dialogue and Synthesis
Authors: Govind Ajit , Wery Jacques , Dessalegn Bezaiet , Elmahdi Amgad , Bishaw Zewdie , Nangia Vinay , Biradar Chandrashekhar , Nisa Zaib Un , Abay Kibrom , Amarnath Giriraj , Breisinger Clemens , Ibrahim Nabil Ahmed , Kleinermann Charles , Niane Abdoul Aziz , Thijssen Marja
Published: November 2021

Agriculture and agri-food systems of the highly vulnerable Middle East and North Africa (MENA) region needs a radical transformation under a changing climate. Based on a two-year effort, initially we developed a mega hypothesis on how to achieve climate-smart agri-food transformation in the region. In the study, we hypothesized that “Climate-Smart Lifts” implemented in the enabling environments can rapidly facilitate agri-food transformation in the region. In order to gather the stakeholders’ perception about this, we organized a collective conversation among ~400 stakeholders that represent various scales and sectors within the agriculture sector in MENA. These “listening cum learning consultations” were conducted through a survey followed by a series of webinars. The webinar discussions were strategically guided based on our hypothesis, the responses from the surveys and the regional needs. These discussions provided a forum to bring-out the stakeholders’ perspective on what new knowledge, partnerships, instruments and projects were needed in the MENA. The deliberation focused on the opportunities of public–private partnerships focusing in all the four major agroecosystems in MENA (irrigated, rainfed, rangelands, and deserts). In result, we developed an effective framework for strategic resource mobilization in the region, keeping in view the strong regional needs for climate actions and the requisite long-term commitments for the SDGs implementation.
Sweet vs. Salty Former Food Products in Post-Weaning Piglets: Effects on Growth, Apparent Total Tract Digestibility and Blood Metabolites
Authors: Luciano Alice , Tretola Marco , Mazzoleni Sharon , Rovere Nicoletta , Fumagalli Francesca , Ferrari Luca , Comi Marcello , Ottoboni Matteo , Pinotti Luciano
Published: November 2021

Former food products (FFPs) have a great potential to replace conventional feed ingredients. This study aimed to investigate the possibility to partially replace standard ingredients with two different types of FFPs: bakery (FFPs-B) or confectionary (FFPs-C) FFPs and their effects on growth performances, feed digestibility and metabolic status in post-weaning piglets. Thirty-six post-weaning piglets were randomly assigned to three experimental diets (n = 12 per diet) for 42 days: a standard diet (CTR), a diet where 30% of standard ingredients were replaced by confectionary FFPs (FFPs-C) and a diet where 30% of standard ingredients were replaced by bakery FFPs (FFPs-B). Individual body weight and fecal dry matter were measured weekly. Feed intake (FI) was determined daily. Average daily gain (ADG), average daily feed intake (ADFI) and feed conversion ratio (FCR) were calculated. Fecal samples were collected daily for three days/week to determine apparent total tract digestibility of dry matter (ATTD). At day 0, 21 and 42, blood samples were collected from all the piglets. No significant differences (p > 0.05) between groups were found in growth performances and metabolic profile. However, ATTD in FFPs-B group was lower (p < 0.05) compared to the CTR group at the end of the experiment. This study confirmed the possibility to formulate homogeneous diets integrated with 30% of both categories of FFPs. Further investigations are needed to clarify the effects of bakery former food products on the digestibility of the diet.
Effects of Compost-Bedded Pack Barn on Circulating Cortisol and Beta-Endorphins in Dairy Cows: A Case Study
Authors: Odore Rosangela , Biasato Ilaria , Gardini Giulia , D’Angelo Antonio , Bellino Claudio
Published: November 2021

The up-to-date literature suggests that the compost-bedded pack barn housing system is capable of remarkably improving productive and reproductive performance, as well as health status and welfare, in dairy cattle. However, there is currently limited knowledge available on the endocrine and biochemical changes in animals housed in such alternative systems. Therefore, this study aimed to measure blood cortisol (COR) and beta-endorphins (BE) in 22 two-year-old primiparae Fleckvieh cows, who were randomly allotted to the following two different housing systems: CB (n = 11) and FB (n = 11). Blood samples were collected at the beginning of the experiment (T0) and every two months thereafter (T1, T2, and T3). The COR and BE were measured through an immunoenzymatic kit. With the only exception being T0, no differences were observed over time between the two groups, neither for COR nor for BE. However, the blood cortisol levels of the CB cows decreased over time, while a T1 peak was identified in the FB group. On the contrary, both the housing systems displayed numerically higher BE at T3 than at the other experimental times. Therefore, the overall data suggest that the compost-bedded pack barn did not significantly affect the studied parameters. Accordingly, cow welfare should be assessed using a wider panel of animal-based indicators.
The Influence of Dietary Gallic Acid on Growth Performance and Plasma Antioxidant Status of High and Low Weaning Weight Piglets
Authors: Zhao Xuemei , Wang Jizhe , Gao Ge , Bontempo Valentino , Chen Chiqing , Schroyen Martine , Li Xilong , Jiang Xianren
Published: November 2021

This study evaluated the effects of dietary gallic acid (GA) on growth performance, diarrhea incidence and plasma antioxidant status of weaned piglets regardless of whether weaning weight was high or low. A total of 120 weaned piglets were randomly allocated to four treatments in a 42-day experiment with a 2 × 2 factorial treatment arrangement comparing different weaning weights (high weight (HW) or low weight (LW), 8.49 ± 0.18 kg vs. 5.45 ± 0.13 kg) and dietary treatment (without supplementation (CT) or with supplementation of 400 mg/kg of GA). The results showed that HW piglets exhibited better growth performance and plasma antioxidant capacity. Piglets supplemented with GA had higher body weight (BW) on day 42 and average daily gain (ADG) from day 0 to 42 compared to the control piglets, which is mainly attributed to the specific improvement on BW and ADG of LW piglets by the supplementation of GA. The decreased values of diarrhea incidence were seen in piglets fed GA, more particularly in LW piglets. In addition, dietary GA numerically reduced malondialdehyde (MDA) content in plasma of LW piglets. In conclusion, our study suggests that dietary GA may especially improve the growth and health in LW weaned piglets.
Pattern and Appropriateness of Antimicrobial Prescriptions for Upper Respiratory Tract and Dental Infections in Male Prisoners in Italy
Authors: Di Giuseppe Gabriella , Lanzano Raffaele , Silvestro Armando , Napolitano Francesco , Pavia Maria
Published: November 2021

Background: This study explored the antimicrobial prescribing pattern for upper respiratory tract and dental infections in prisoners in Italy, with specific attention paid to the appropriateness of indication and its potential determinants. Methods: This investigation was conducted through the consultation of clinical records of adult male inmates in a prison in the south of Italy. Results: Prescription of antimicrobials for upper respiratory tract infections ranged from 41.9% in influenza diagnoses to 88% in pharyngitis diagnoses, with high prevalence also for bronchitis (73.5%) and common cold (57.7%), and those for dental infections ranged from 82% in pulp necrosis and symptomatic apical periodontitis/pulp necrosis and localized acute apical abscess diagnoses, to 85.7% in symptomatic irreversible pulpitis with or without symptomatic apical periodontitis diagnoses. The most frequently prescribed antimicrobial was amoxicillin and clavulanic acid (33.8%), followed by amoxicillin (26.5%), macrolides (19.8%) and third-generation cephalosporins (7.9%). The overall antimicrobial overprescription was 69.4%, whereas an antimicrobial prescription was provided in all 52 cases in which it was indicated. The inappropriate antimicrobial prescriptions were significantly less likely for bronchitis, influenza and symptomatic irreversible pulpitis with or without symptomatic apical periodontitis compared to common cold/pharyngitis/rhinosinusitis, and when the antimicrobial prescription was provided by medical specialists compared to prison physicians, whereas antimicrobial overprescriptions without indications were significantly more frequent in patients with underlying chronic clinical conditions. Conclusions: A concerning widespread practice of inappropriate antimicrobial prescriptions in prisoners was found. Diagnoses-specific monitoring of antimicrobial use and prison-focused antimicrobial stewardship policies are strongly needed.
Characterization, Antioxidant and Antitumor Activities of Oligosaccharides Isolated from Evodia lepta (Spreng) Merr. by Different Extraction Methods
Authors: Xiong Feng , Liang Hui-Xian , Zhang Zhi-Jing , Mahmud Taifo , Chan Albert S. C. , Li Xia , Lan Wen-Jian
Published: November 2021

Evodia lepta (E. lepta) is a traditional Chinese herbal medicine with various biological activities. One of the active components of this widely used medicinal plant is believed to be an oligosaccharide. The extraction yields, structural characteristics, antioxidant, and antitumor activities of four oligosaccharide extracts obtained by hot water extraction (HEO), ultrasound-assisted extraction (UEO), enzyme-assisted (EEO), and microwave-assisted extraction (MEO) were investigated. Matrix-assisted laser desorption/ionization-time of flight-mass spectrometry (MALDI-TOF-MS), X-ray diffraction (XRD), and Scanning electron microscopy (SEM) results indicated that the extraction methods had a difference on the molecular mass distribution, structure, and morphology of the EOs. In addition, HEO and MEO showed strong antioxidant activities, which might be related to their uronic acid and protein contents. More interestingly, MEO was more active toward MDA-MB-231 cells compared to other cells, and cell growth inhibition was proposed to occur through apoptosis. Overall, microwave-assisted extraction is a promising technique for the extraction of high quality EO.
Theoretical Investigation on the Impact of Two HDR Dampers on First Modal Damping Ratio of Stay Cable
Authors: Nguyen Duy Thao , Vo Duy Hung , Haque Md. Naimul
Published: November 2021

Stay cables are one of the vital components of a cable-stayed bridge. Due to their flexible nature, stay cables are vulnerable to external excitation and often vibrate with large amplitude under wind action which leads to the fatigue failure of the cables. To suppress such kind of large amplitude vibration by improving the damping ratio of the cable various dampers such as magnetorheological damper, friction damper; oil damper; or high damping rubber (HDR) damper are utilized and gained popularity over time. This paper focuses on improving the damping ratio of stay cables using a combination of two HDR dampers. First, the theoretical model is formulated considering cable bending stiffness to evaluate the damping effect of cable-HDR dampers system. Then, the impact of various design parameters of HDR dampers on cable damping considering the cable stiffness is performed. The comparative analysis of results shows that the considered parameters such as loss factor, spring factor, and installation location of dampers have much effect on the stay cables damping ratio. Finally, the optimal parameters of the two HDR dampers are proposed for damper design.
Ultrasonic Surface Rolling Process: Properties, Characterization, and Applications
Authors: John Merbin , Ralls Alessandro M. , Dooley Scott C. , Thazhathidathil Akhil Kishore Vellooridathil , Perka Ashok Kumar , Kuruveri Udaya Bhat , Menezes Pradeep L.
Published: November 2021

Ultrasonic surface rolling process (USRP) is a novel surface severe plastic deformation (SPD) method that integrates ultrasonic impact peening (UIP) and deep rolling (DR) to enhance the surface integrity and surface mechanical properties of engineering materials. USRP can induce gradient nanostructured surface (GNS) layers on the substrate, providing superior mechanical properties, thus preventing premature material failure. Herein, a comprehensive overview of current-state-of-the art USRP is provided. More specifically, the effect of the USRP on a broad range of materials exclusively used for aerospace, automotive, nuclear, and chemical industries is explained. Furthermore, the effect of USRP on different mechanical properties, such as hardness, tensile, fatigue, wear resistance, residual stress, corrosion resistance, and surface roughness are summarized. In addition, the effect of USRP on grain refinement and the formation of gradient microstructure is discussed. Finally, this study elucidates the application and recent advances of the USRP process.
Estimating Critical Latency Affecting Ship’s Collision in Re-Mote Maneuvering of Autonomous Ships
Authors: Yim Jeong-Bin , Park Deuk-Jin
Published: November 2021

Estimation of the critical latency that can cause collision in remote maneuvering of autonomous ships can provide a clue to avoid collisions. The concept of estimating the critical latency was established using the turning circle formed by the turning maneuver of the own ship, and critical latency was estimated using the radius of the turning circle with the turning time ratio. The turning circle was observed using the turning trajectory of the give-way vessel measured in the ship maneuvering simulation experiment. Experimental results demonstrated that the proposed method is capable of identifying both the location and time of the collision due to critical latency. As a result, a clue to avoid possible collision in remote maneuvering caused by critical latency was deduced.
Strategies for 3D Modelling of Buildings from Airborne Laser Scanner and Photogrammetric Data Based on Free-Form and Model-Driven Methods: The Case Study of the Old Town Centre of Bordeaux (France)
Authors: Costantino Domenica , Vozza Gabriele , Alfio Vincenzo Saverio , Pepe Massimiliano
Published: November 2021

This paper presents a data-driven free-form modelling method dedicated to the parametric modelling of buildings with complex shapes located in particularly valuable Old Town Centres, using Airborne LiDAR Scanning (ALS) data and aerial imagery. The method aims to reconstruct and preserve the input point cloud based on the relative density of the data. The method is based on geometric operations, iterative transformations between point clouds, meshes, and shape identification. The method was applied on a few buildings located in the Old Town Centre of Bordeaux (France). The 3D model produced shows a mean distance to the point cloud of 0.058 m and a standard deviation of 0.664 m. In addition, the incidence of building footprint segmentation techniques in automatic and interactive model-driven modelling was investigated and, in order to identify the best approach, six different segmentation methods were tested. The segmentation was performed based on the footprints derived from Digital Surface Model (DSM), point cloud, nadir images, and OpenStreetMap (OSM). The comparison between the models shows that the segmentation that produces the most accurate and precise model is the interactive segmentation based on nadir images. This research also shows that in modelling complex structures, the model-driven method can achieve high levels of accuracy by including an interactive editing phase in building 3D models.
Development of Dialogue Management System for Banking Services
Authors: Rustamov Samir , Bayramova Aygul , Alasgarov Emin
Published: November 2021

Rapid increase in conversational AI and user chat data lead to intensive development of dialogue management systems (DMS) for various industries. Yet, for low-resource languages, such as Azerbaijani, very little research has been conducted. The main purpose of this work is to experiment with various DMS pipeline set-ups to decide on the most appropriate natural language understanding and dialogue manager settings. In our project, we designed and evaluated different DMS pipelines with respect to the conversational text data obtained from one of the leading retail banks in Azerbaijan. In the work, the main two components of DMS—Natural language Understanding (NLU) and Dialogue Manager—have been investigated. In the first step of NLU, we utilized a language identification (LI) component for language detection. We investigated both built-in LI methods such as fastText and custom machine learning (ML) models trained on the domain-based dataset. The second step of the work was a comparison of the classic ML classifiers (logistic regression, neural networks, and SVM) and Dual Intent and Entity Transformer (DIET) architecture for user intention detection. In these experiments we used different combinations of feature extractors such as CountVectorizer, Term Frequency-Inverse Document Frequency (TF-IDF) Vectorizer, and word embeddings for both word and character n-gram based tokens. To extract important information from the text messages, Named Entity Extraction (NER) component was added to the pipeline. The best NER model was chosen among conditional random fields (CRF) tagger, deep neural networks (DNN), models and build in entity extraction component inside DIET architecture. Obtained entity tags fed to the Dialogue Management module as features. All NLU set-ups were followed by the Dialogue Management module that contains a Rule-based Policy to handle FAQs and chitchats as well as a Transformer Embedding Dialogue (TED) Policy to handle more complex and unexpected dialogue inputs. As a result, we suggest a DMS pipeline for a financial assistant, which is capable of identifying intentions, named entities, and a language of text followed by policies that allow generating a proper response (based on the designed dialogues) and suggesting the best next action.
Conceptual Solution Decision Based on Rough Sets and Shapley Value for Product-Service System: Customer Value-Economic Objective Trade-Off Perspective
Authors: Feng Di , Fu Xiaoyun , Jiang Shaofei , Jing Liting
Published: November 2021

The product service system (PSS), as a design concept for integrated products and services, needs to be evaluated in the early design stage to maximize the value for stakeholders of the PSS concept, which is a crucial task for enterprises. However, existing methods focus on the ranking and value assessment of PSS evaluation criteria (e.g., quality, sustainability, cost), ignoring the needs conflict between customer value and economic objectives in PSS design, resulting in decision results that are not applicable to industrial enterprises. Furthermore, the influence of weight preference and uncertain information on solution evaluation is seldom considered when calculating the weight of each criterion. To fill this gap, integrating rough sets and the Shapley value decision approach for product-service system design considering customer value-economic objective trade-off is proposed, which mainly includes two parts: firstly, the best worst method (BWM) and the entropy weight method are integrated to obtain the comprehensive weight of evaluation criteria in the customer value and economic objectives; secondly, the Shapley value method in the coalition game is used to solve the optimal expectation allocation of the two objectives, so as to select the solution closest to the allocation, i.e., the optimal solution. In addition, rough set techniques are used to capture and integrate subjective assessment information originating from DMs under uncertainty. Finally, a case study of the electric forklift design is illustrated to verify the proposed decision model. The decision results show that this approach is more reliable through sensitivity and comparison analysis, and provide a valuable recommendation for enterprises to consider product service in forklift design.
Hydraulic Fracture Propagation Near the Cavity in a Poroelastic Media
Authors: Azarov Anton , Patutin Andrey , Serdyukov Sergey
Published: November 2021

In this paper, we investigate the problem of the propagation of hydraulic fractures in a poroelastic medium that has a circular cavity. The research was conducted using the extended finite element method (XFEM) implemented in the ABAQUS software package. The problem was considered in a plane formulation. The initial crack was oriented parallel to the surface of the cavity. It was shown that the path of the hydraulic fracture depends strongly on the hydrostatic stress in the medium and the distance between the crack and the cavity. We studied the influences of the poroelastic parameters, such as permeability and the Biot coefficient, on the propagation of cracks. It was shown that the cracks were less curved when the coupled problem of poroelasticity was considered. The features of fluid pressure changes inside the fracture and at the opening of the mouth were studied. It was shown that the fluid pressure in the fracture during injection was minimally sensitive to the state of the stress in the medium, to the position of the initial crack, and to the poroelastic parameters. The solution to the problem in this setting can be used to simulate hydraulic fracturing close to mine workings during a controlled roof’s collapse to prevent it from hanging, and the formation of impervious screens to reduce airflow from the mine to degassing boreholes through the rock, for example.
Novel Beam Scan Method of Fabry–Perot Cavity (FPC) Antennas
Authors: Jang Wook , Jeon Yeong-geun , Maeng Han-jun , Kim Jongyeong , Kim Dongho
Published: November 2021

A new beam scanning method of a Fabry–Perot cavity (FPC) antenna is proposed. To obtain high gain in a target direction with a reduced sidelobe level (SLL), we devised a tapered partially reflective surface (PRS) as a superstrate. Moreover, to attain various beam scanning directions, a phase-controllable artificial magnetic conductor (AMC) ground plane with a broad reflection phase range and high reflection magnitudes was introduced. In the proposed method, a new formula to satisfy an FP resonance condition in a cavity for a scanned beam is also suggested. According to the formula, the FPC antenna can precisely scan the main beam in designed target directions with well-maintained high gain, which has been hardly achievable. In addition, our method demonstrates the potential of electrical beam-scanning antennas by employing active RF chips on the AMC cells. To validate the method, we fabricated a prototype FPC antenna for a scanned beam at θ = 30°. Furthermore, we conducted an additional simulation for a different beam scanning angle as well. Good agreement between the expected and experimental results verifies our design approach.