bluuebunny/crossref_metadata_2025 huggingface dataset:
Acute Kidney Injury and Risk Factors in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation
Authors: Avcı Begüm , Bilir Özlem Arman , Özlü Sare Gülfem , Kanbur Şerife Mehtap , Gökçebay Dilek Gürlek , Bozkaya İkbal Ok , Bayrakçı Umut Selda , Özbek Namık Yaşar
Published: May 2023

Background Acute kidney injury (AKI) is common complication of hematopoietic stem cell transplantation (HSCT) with increased mortality and morbidity. Understading the risk factors for AKI is essential. The aim of this study is to identify AKI incidence, risk factors, and prognosis in pediatric post- HSCT patients.Methods We conducted a retrospective case-control study of 278 patients who were divided into two groups: those with AKI and those without AKI (Non-AKI). The groups were compared in terms of characteristics and clinical symptoms of patients, and post-HSCT complications, nephrotoxic drug use. Logistic regression analysis was applied to determine the risk factors for AKI.Results A total of 16.9% of patients had acute kidney injury, with 8.5% requiring kidney replacement therapy. Older age (OR 1.129, 95% CI 1.061-1.200, p < .001), sinusoidal obstruction syndrome (OR 2.562, 95% CI 1.216–5.398, p = .011), hemorrhagic cystitis (OR 2.703, 95% CI 1.178–6.199, p = .016), and nephrotoxic drugs, including calcineurin inhibitors, amikacin, and vancomycin (OR 17.250, 95% CI 2.329-127.742, p < .001), were identified as significant independent risk factors for AKI following HSCT. Mortality rate and mortality due to AKI were higher in stage 3 patients than those in stage 1 and 2 AKI (p = .019, p = .007, respectively). Chronic kidney disease developed in 1 patient (0.4%), who was in stage 1 AKI (2.1%).Conclusion AKI poses a serious threat to children post-HSCT, leading to alarming rates of mortality and morbidity. To enhance outcomes and mitigate these risks, it is vital to identify AKI risk factors, adopt early preventive strategies, and closely monitor this patient group.
Numerical and analytical estimation of rolling force and torque in hot strip rolling
Authors: Attanasio Aldo , Prete Antonio Del , Primo Teresa
Published: May 2023

In this paper, both numerical and analytical method were developed for computing, in strip or plate rolling, the distribution of roll pressure, rolling force and rolling torque (from which also rolling power can be estimated), assuming an homogeneous deformation of the rolled material. Differently to other similar models present in literature, which solve the resulting rolling differential equation for the roll pressure, the model presented in this work solves the problem for the horizontal force. In this way it is possible to avoid the calculation of the derivative of material flow stress curve, which is not always analytically easy and possible (i.e. point material flow stress data). The proposed numerical model is based on the friction law proposed by Chen and Kobayashi while the analytical one is based on simple shear friction model and brings to useful analytical formulas for a quickly calculation of rolling torque and force. Moreover, a relationship between the shear friction factor and Coulomb friction coefficient in rolling was found. The developed models show good agreement with experimental measures, in terms of rolling force and torque, found in literature.
Industrial Symbiosis and Circularization: Optimal Shelf Life of Waste-based Briquettes
Authors: Ossei-Bremang Rejoice Ntiriwaa , Adjei Eunice Akyereko , Kemausour Francis , Gyenin Eric Kwasi
Published: May 2023

The fusion of the circular economy and industrial symbiosis has several advantages from an economic and developmental standpoint. Cooking energy security issues in Africa can partly be solved by the utilization of waste resources in energy technology decisions such as briquetting. However, one of the limitations associated with waste-based briquettes has been identified as a reduction in efficiency when stored for a long period of time under varied storage conditions. The aim of this study was to ascertain the effects of storage time and exposure on the calorific value and mechanical characteristics of a waste-based composite briquette made from oil palm shell and decanter cake after 180 days of storage. The calorific value decreased by 12.99% and 31.40%, respectively, for sealed packaged storage and open-air storage. On the 180th day of the experiment, the packaged storage and the open-air storage registered 1000.48 Kg/m3 and 870 Kg/m3, 72.34% and 100%, 712% and 895%, and 118% and 143% for relaxed densities, shatter indices, resistance to impact, and hygroscopic properties respectively. Manufacturers within West Africa can adopt the findings in this study as a guide for their processes.
Privatization Decisions in a Mixed Duopoly under Endogenous Product Differentiation
Authors: Wang Fangyan , Munoz-Garcia Felix
Published: May 2023

We examine how endogenous product differentiation affects the behavior of a mixed duopoly market where a private firm competes with a partially privatized public firm under both Cournot and Bertrand competition. We also analytically derive the optimal degree of partial privatization of the public firm. Generally, privatizations increase the likelihood of no firm investing in equilibrium, resulting in markets with more homogenous goods. The public firm is more motivated to invest in product differentiation, particularly when prioritizing social welfare, while the private firm undertakes more investments when investments are not highly effective under Bertrand competition. We also demonstrate that a complete nationalization is not necessarily optimal in all contexts, and whether regulators privatize more or less depends on different market settings. Partial privatizations can enhance welfare when firms compete in quantities and investments in product differentiation are moderately effective. However, complete nationalization is socially optimal when firms compete in prices.
JEL classification: D43, L13, L32, L33
Synergistic Adsorption/Photodegradation of Ciprofloxacin by UV light-driven Nanocomposite Photocatalyst of Cu doped AC/TiO2: Experimental design via RSM-CCD.
Authors: Yaacob N. A. , Khasri A. , Ridzuan M. J.M. , Salleh N. H. M. , Chaijak P.
Published: May 2023

Improving the adsorption ability of titanium dioxide (TiO2) has been considered as a promising strategy to promote its photodegradation of pollutant for the wastewater treatment. Hence, the statistical optimization by using central composite design-response surface methodology for the synthesizing of Cu doped AC/TiO2 nanocomposite photocatalyst via microwave-assisted sol-gel method was prepared, and then applied in adsorption/photodegradation for Ciprofloxacin (CFx) removal. From analysis of variance analysis, the findings show 95 % removal of CFx within 120 min in a batch system at the optimum preparation parameters of AC/TiO2 ratio = 0.50, Cu dosage = 0.32 g, irradiation power = 477 W, and irradiation time = 14 min. Kinetic studies displayed that the kinetic data was well described by Pseudo second-order models. Also, the isotherms data was well fitted by Langmuir model, with maximum adsorption capacity of 200 . Radical quenching test indicated that hydroxyl radical (•OH) was found to be the reactive radical that generally play the primary role in adsorption/photodegradation of CFx removal. The synergetic mechanisms of adsorption/photodegradation of CFx removal by Cu doped AC/TiO2 nanocomposite photocatalyst was mainly done by photogenerated electron-hole pair and hydroxyl radicals. The results of this study indicated that the prepared Cu doped AC/TiO2 nanocomposite photocatalyst is a high potential of sustainable photocatalyst for CFx removal in aqueous solution using adsorption/photodegradation under UV light irradiation.
Online questionnaire based evaluation of knowledge, attitude and practices (KAP) regarding dengue fever among local people of Karachi, Pakistan.
Authors: Ali Muhammad , Khan Quratulain , Nawaz Shoaib , Naz Sharmeen , Bilal Muhammad , Abbas Mahnoor
Published: May 2023

Dengue fever is a very common viral disease in Pakistan. It is a major public health issue whose epidemiology and ecology is strongly related to human lifestyle and activities. Current study aimed at evaluation of Knowledge, attitude and practices regarding dengue fever among people of Karachi, Pakistan. A questionnaire based cross sectional study was conducted between February-April 2022. Questionnaire was prepared and adapted from previous literature available and it was designed on Google forms. This questionnaire was distributed randomly through various social media networks. Questionnaire had four sections which included socio-demographic data of all Participants, questions about knowledge, attitude and practice of dengue fever. Data was evaluated statistically (descriptive statistics) using SPSS software version 25. A total of 140 respondents filled the Google survey form. Out of 140 respondents or participants (42.9%) were male and (57.1%) were female. Majority of participants (80%) were between age group of 15–30 years. Participants have different educational status i.e. undergraduate participants were 57.1% and postgraduate were 32.9%. Majority of participants were single (72.1%) and students (70%). Ninty percent of people reported that they had heard about dengue fever. Dengue as a viral disease was reported by 72.1% but still 50.7% thought that antibiotics are used as treatment of dengue fever. Panadol reduces the intensity of dengue fever was reported by 49.3% respondents. Only 26.4% respondents participated in awareness programs related to dengue fever. Positive perception regarding visit to a physician after getting dengue fever was given by 74.3%. The knowledge about dengue fever was adequate in local community or people of Karachi, Pakistan, while the attitude and practices regarding life style modification requires immediate improvements. Good knowledge doesn't necessarily lead to good practice and positive perception. It is high time that awareness and educational campaigns on dengue fever should be designed by government to improve behavior and practices of prevention and control of dengue fever.
Arqueología de un recuerdo
Authors: Zuluaga Mesa David Esteban
Published: May 2023

Ayer fue un día de fuertes revelaciones, Coco. Te las contaré si así lo quieres. Hay una mujer que seguro conoces, ella sabe de ti, es muy probable que la hayas visto también, que hayamos coincidido los tres en algún encuentro o tal vez la recuerdes por algún paso por nuestra casa. Esa mujer llegó a mi vida un poco antes que tú, te vio crecer como idea, como boceto y luego se puso feliz al ver cómo te veías con tus patitas popochas y tus ojos de puntitos. También me vio escribir otros libros menos importantes, más serios. Y fue pretexto de muchas de las frases que puse a circular en internet y de un pequeño libro —Cartas para una mujer Amarilla— al que la inversión de tiempo no le hizo justicia, pese a sus seis versiones. Al parecer nunca pude desligarlo de la emoción: una catástrofe para los editores.
Impact of the US unconventional monetary policy in times of crises on Vietnam
Authors: Sy Ngo Nam , Thanh Doan Ha
Published: May 2023

The study investigates the effects of the US unconventional monetary policy on the Vietnamese economy, focusing on the output and price index. Besides, the differences in the response of these indicators to the shock related to non-traditional tools implemented by the US in the Global Financial Crisis and during the pandemic crisis are also explored. By applying the Structural Vector Autoregressive model on the monthly dataset from January 2007 to April 2022, the results show that an expansionary monetary policy of the US by unconventional measures leads to a rise in the output and price index of Vietnam. In addition, risk-taking channels and portfolio rebalancing channels are important in the transmission of the US monetary policy to Vietnam, they cause booms in asset prices via the surge of capital flows. Moreover, another important finding is that the impact of US UMP on the Vietnamese economy during the Global Financial Crisis was generally two times higher than during the epidemic crisis.
The place of antispasmodic drugs in modern therapy of irritable bowel syndrome
Authors: Khalaidzheva K. N. , Drozdov V. N. , Shikh E. V. , Serebrova S. Yu.
Published: May 2023

Irritable bowel syndrome (IBS) is a common functional disease of the gastrointestinal tract, affecting a large number of adults worldwide, and leads to a significant decrease in the quality of life. IBS places a heavy burden on patients, most of whom are able-bodied population, as well as doctors and the healthcare system. The pathogenesis of this disease is multifactorial and includes the brain-intestine axis, disorders of the immune function of the mucous membrane, visceral hypersensitivity, changes in the motility of the gastrointestinal tract, changes in the microbial composition of the intestine. Based on the fact that changes in  intestinal motility and visceral hypersensitivity are among the  key factors in  the pathogenesis of  the disease, he use of antispasmodic drugs as part of complex therapy is justified. Mebeverin is a myotropic antispasmodic drug recommended for  use in  patients with IBS according to Rome IV Criteria, as well as clinical recommendations of  the Russian Gastroenterological Association and the Association of Coloproctologists of Russia. According to available data, mebeverin has proven to be an effective and safe antispasmodic used to treat patients with IBS. The article presents a clinical case demonstrating the  experience of  effective use of  the drug Mebespalin®. A  patient with a  diagnosis of  IBS with a  predominance of constipation is recommended to take an antispasmodic, as well as lifestyle modification – the addition of fiber-rich foods, sufficient drinking regime and increased physical activity. A week after the start of treatment, the patient noted an improvement in her condition – abdominal pain did not bother, the stool normalized.
The influence of structural and functional albumin properties on the life quality in patients with decompensated liver cirrhosis
Authors: Turkina A. A. , Maevskaya M. V. , Zharkova M. S. , Ivashkin V. T.
Published: May 2023

Introduction. The gradual progression of liver cirrhosis with the development of complications has a negative impact on the life quality of patients with this disease. Modern therapeutic strategies are aimed not only at disease compensating, but much attention is paid to improving the quality of life. No data exists on the effect of serum albumin levels, their structural and functional activity, on the quality of life of patients with cirrhosis. Aim. To evaluate the  relationship between serum albumin concentration, its structural configuration  (DR), functional properties (BE, RTQ, DTE) and life quality in patients with decompensated liver cirrhosis. Materials and methods. The severity of the structural and functional properties of albumin was evaluated in decompensated patients (n = 50) using electron paramagnetic resonance spectroscopy (EPR spectroscopy). Patients’ quality of life was examined using a standardised SF-36 questionnaire.Results. Pathological changes in DR were observed in 100% of patients, a decrease in BE – in 90%, a violation of RTQ – in 82% of cases, a decrease in DTE was recorded in 76% of patients. The correlation between the level of serum albumin and indicators of physical functioning (PF), role functioning due to emotional state (RE) was ρ = 0,294. Structural and functional albumin properties were related to low indicators of the physical component of health (p < 0,05). Conclusions. А decline in serum albumin levels, a violation of its conformation and functional properties has a negative impact on the quality of life of patients with decompensated liver cirrhosis.
Antacids in real clinical practice
Authors: Trukhan D. I. , Degovtsov E. N. , Novikov A. Yu.
Published: May 2023

Currently, proton pump inhibitors (PPIs), H2-histamine receptor blockers (H2-blockers), antacids, and anticholinergics are used to treat acid-dependent diseases of the gastrointestinal tract. PPIs are considered the most effective drugs for the treatment of acid-dependent diseases of the gastrointestinal tract. However, in real clinical practice, interest remains in the use of antacids in  acid-dependent diseases. This is due to the  fact that antacids not only adsorb hydrochloric acid in  the gastric lumen (by buffering the HCl present in the stomach, without a significant effect on its production) and reduce the proteolytic activity of gastric juice (reducing/ neutralizing the activity of pepsin), but also have a number of other pharmacotherapeutic properties demanded by the gastroenterological patient. Antacids in addition to antisecretory action have: 1) cytoprotective, primarily gastroprotective, action, which is mediated by: a) stimulation of the synthesis of bicarbonates and prostaglandins; b) mucoprotection – an increase in the production of protective mucus by epithelial cells; c) switching of the epithelial growth factor and its concentration in the area of erosive and ulcerative defects, which in turn activates angiogenesis, cell proliferation and local reparative and regenerative processes; 2) enveloping and adsorbing action, through chelation of lysolecithin and bile acids, which have an aggressive damaging effect on the upper gastrointestinal tract; 3) regulate gastroduodenal motility due to: a) antispasmodic action and streamlining gastroduodenal evacuation; b) decrease in intracavitary pressure in  the stomach and duodenum; b) obstacles to the  formation of  duodenogastric reflux. To date, combined preparations, the  basic composition of  which includes magnesium hydroxide and aluminum hydroxide, meet the  basic requirements for non-absorbable antacids. In conclusion, the authors present a number of clinical situations, indicating that today rationally prescribed antacid drugs successfully and significantly solve the main tasks of symptomatic therapy of acid-dependent and other diseases of the gastrointestinal tract, significantly improving the quality of life of patients.
APPLICATION OF EFFECTIVE AZIMUTH DIFFERENT FORMULA IN DETERMINING THE QIBLA DIRECTION
Authors: Ahmad Auzi'ni Syukron Kamal , Shabir Muslich
Published: May 2023

The sun's shadow and the Qibla azimuth are two techniques for figuring out the Qibla direction. To obtain Qibla direction accuracy while applied to traditional instruments with low accuracy, such istiwa'ayn, the user's accuracy is required. Slamet Hambali's theory of a process angle was inspired by this issue. The effective angle disparity formula, which is based on Slamet Hambali's concept, is discussed in this article along with how it can be used to get effective azimuth variance. This article is based on numerically-based quantitative research using library data. The aim is to comprehend the concept of various effective azimuths and how they are used to identify the direction of the Qibla. This article comes to the conclusion that Slamet Hambali's formula for the effective azimuth difference tends to make use of the idea of processing angle by calculating the azimuth difference value with particular aiming hours, azimuth difference value, and processing angle to produce a shooting clock with a different azimuth valuation.Kata kunci : azimut, efektif, jam bidik
Sensitivity analysis of numerical model parameters for optimized PEH responses
Authors: Gljušćić Petar , Zelenika Saša
Published: May 2023

With the increasing popularity of wearable devices, typically employed in fitness and health monitoring, there is an evident need to extend their autonomy and replace the conventional power sources with environmentally friendly alternatives. Piezoelectric energy harvesting systems, optimized for collecting kinetic energy from random human motion and transduce it into electrical energy, represent a viable option for powering autonomous wearables. Since established analytical methods are unable to model the behaviour of piezoelectric harvesters with complex optimized geometries, suitable numerical models need to be employed for their design. This implies the need of a thorough study focused on the mechanical engineering design optimization purposes of how the finite element type and mesh density affect the uncoupled modal and coupled transient responses of a new class of optimised design configurations of the studied devices.
Microplastic pollution of drinking water in a metropolis
Authors: Buyukunal Serkan Kemal , Koluman Ahmet , Muratoglu Karlo
Published: May 2023

This study was conducted to identify microplastics (MPs) in drinking water from various sources in İstanbul that are known to pose potential health risks. One hundred drinking water samples were analysed. Samples were filtered with a glass filter (Ø: 1.0 μm). After filtration, microscopy was used, followed by SEM-EDS and ATR-FTIR identification to characterise MPs. Two shapes (fibers and fragments) and eight polymer types of MPs (ethylene propylene, neoprene, polyethylene, polyethylene terephthalate, polypropylene, polyvinyl chloride, polytetrafluoroethylene, vinyl chloride vinyl acetate copolymer) with sizes of 12–4892 µm (548 ± 777 µm) were detected. These MPs abundances ranged from 10 to 390 MP L−1 (134 ± 93 MP L−1). In the identification of MPs detected in filters by FTIR spectroscopy, bisphenol A, which is used in the production of various plastics and described as an important public health problem, was detected in 9.74% of MPs. Within the scope of the Sustainable Development Goals, UNEP has a specific objective of ensuring access to safe, affordable drinking water (SDG 6). With a clear statement, it should be emphasised that MPs are a significant barrier to the provision of safe drinking water, and a comprehensive plan for overcoming this barrier should be developed.
Effectiveness of the Neuroimaging Techniques in the Recognition of Psychiatric
Disorders: A Systematic Review and Meta-analysis of RCTs
Authors: Wu Jun , Xiao Jian
Published: May 2023

Background:

Neuroimaging has helped us learn about the stages of brain development from infancy to maturity. Neuroimaging helps physicians diagnose mental illnesses and find novel treatments for them. It can distinguish depression from neurodegenerative diseases or brain tumors, and it can reveal structural defects that cause psychosis. Psychosis has been linked to lesions in the frontal or temporal lobes of the brain, as well as the thalamus and hypothalamus, which can be detected using a brain scan for mental illnesses. Neuroimaging uses quantitative and computational methods to explore the central nervous system. It can detect brain injuries and psychological illnesses. Thus, a systematic review and meta-analysis of randomized controlled trials using neuroimaging to detect psychiatric disorders assessed their efficacy and benefits.

Materials and Methods:

Appropriate articles were searched from PubMed, MEDLINE, and CENTRAL databases using the appropriate keywords as per the PRISMA guidelines. Randomized controlled trials and open-label studies were included as per the predefined PICOS criteria. Meta-analysis was performed using the RevMan software, and statistical parameters like odds ratio and risk difference were calculated.

Results:

Twelve randomized controlled clinical trials with a total of 655 psychiatric patients were included following the criteria from the year 2000 to
2022. We included studies that use different neuroimaging techniques for the detection of organic brain lesions that would help diagnose
psychiatric disorders. The primary outcome was detecting brain abnormalities in diverse psychiatric illnesses with neuroimaging versus
conventional methods. We found the odds ratio value of 2.29 (95% CI 1.49-3.51). The results were heterogeneous with a Tau2 value of 0.38, chi2
value of 35.48, df value of 11, I2 value of 69%, the z value of 3.78, and p-value less than 0.05. The risk difference is 0.20 (95% CI 0.09 -0.31) with
heterogeneity of Tau2 value of 0.03, chi2 value of 50, df value of 11, I2 value of 78%, the z value of 3.49, and p-value less than 0.05.

Conclusion:

The present meta-analysis strongly recommends the use of neuroimaging techniques for the detection of psychiatric disorders.
Investigate the Epigenetic Connections of Obesity Between Mother and
Child With Machine Learning Methods
Authors: Lu Liancheng , Li Yixue , Huang Tao
Published: May 2023

Introduction:

The prevalence of childhood obesity has been increasing in recent decades,
and epigenetics is a great process to detect the relationship between children’s obesity and their mothers’
obesity. To investigate the epigenetic connections of obesity between mother and child, we analyzed
the saliva DNA methylation profiles from 96 mother-child families. The BMI of both mother and
child was measured.

Methods:

MCFS (Monte Carlo Feature Selection) and IFS (Incremental Feature Selection) methods
were used to select the obesity prediction biomarkers. MCFS analysis indicated that if the child's BMI
was greater than 17.46, the mother was very likely to be obese. In other words, the obesity of child and
mother were highly connected. 17 obesity marker probes corresponding to 18 genes: ADGRA1,
CRYBA2, SRRM4, VIPR2, GRIK2, SLC27A1, CLUHP3, THNSL2, F10, PLEC, HTR3C, ESRRG,
PTPRM, ANKRD11, ZFAND2A, RTN2/PPM1N, TEX101, were selected. Most of them were found to
be related to obesity in literature.

Results:

The results showed whether mothers are obese can be concluded through their children's BMI
and methylation patterns. They can help understand the molecular mechanism of obesity.

Conclusion:

Epigenetics is a great indicator of obesity. Our results suggested that the obesity status between
child and mother was highly correlated. Obesity-related epigenetics changes from the mother remained
in the DNA methylation profile of the child's salivary. DNA methylation can partially reflect the
living environment and lifestyles.
Is There a Role of Vitamin D in Alzheimer’s Disease?
Authors: Plantone Domenico , Pardini Matteo , Caneva Stefano , De Stefano Nicola
Published: May 2023

Alzheimer’s disease (AD) represents the most prevalent type of neurodegenerative dementia
and the sixth leading cause of death worldwide. The so-called “non-calcemic actions” of vitamin D
have been increasingly described, and its insufficiency has already been linked to the onset and
progression of the main neurological diseases, including AD. Immune-mediated Aβ plaque’s phagocytosis
and clearance, immune response, oxidative stress, and mitochondrial function are all influenced
by vitamin D, and these functions are considered relevant in AD pathogenesis. However, it has been
shown that the genomic vitamin D signaling pathway is already impaired in the AD brain, making
things more complicated. In this paper, we aim to summarise the role of vitamin D in AD and review
the results of the supplementation trials in AD patients.
Antiviral with Immune Booster Therapy: Current concept for clinical care in Covid-19
Authors: Kajaria Divya
Published: May 2023

Objective: Objective of the article is to provide a brief overview of novel corona virus, discussing the role of immunity in the pathogenesis, analyzing the comparative efficacy of anti-viral vs. immune- enhancer medicines and propose a stepwise treatment methodology of both these groups of herbs for prevention as well as management of COVID-19. Data Source: Ayurvedic texts including Brihatatrayi (Charaka Samhita, Sushruta Samhita & Astanga Hridyam), Laghutrayi, Nighantus, published article in PubMed, Scopus, Science Direct, Google Scholar, AYUSH Portal, etc., were thoroughly searched for the compilation of information. Review method: Narrative and systematic methods for reviewing the literature and related published article was used Discussion: There is yet no proven drug for the treatment of COVID-19 and therefore presently medicines having substantial evidences are use for the treatment of COVID-19 on trial basis to assess best possible treatment. In this direction, this article provides a framework of treatment methodology according to Ayurveda for the prevention as well as management of COVID-19. Conclusion: The article provides details of anti-viral medicines and immune-boosting medicines described in Ayurveda and give the logistical approach for their sequential use to manage the disease.
Critical review of Rasa Ratna Samuchchaya w.s.r. to its Rasaprabha Teeka
Authors: Hemant Kumar Chandolia  , Neha Verma  , Deepa Dhakad  , Govind Sahay Shukla  , Rajaram Agrawal  , Manisha Goyal
Published: May 2023

Rasa Ratna Samuchchaya (RRS) was written by Rasa Vagbhatta. This text sheds light on the extraction, purification, and transformation of metals and minerals into therapeutically useful forms, as well as the various instruments created for alchemical uses and the use of herbo-mineral preparations to treat a wide range of illnesses. Rasaprabha Teeka of RRS written by Dr. Indradev Tripathi. This Teeka is Hindi commentary of RRS. This Teeka consists total 30 chapters, 3871 verses and detailed description of 960 formulations. The main components of RRS are classification of metals and minerals, descriptions of instruments and formulations and avoiding the use of metals and minerals during pregnancy. RRS covers all eight branches of Ayurveda, although it mainly deals with therapeutic aspects of Rasashastra. Thus, the Rasaprabha Teeka of RRS is a necessary and required book for individuals who wish to learn the fundamentals and in-depth details of Rasashastra and is regarded as one of the most important reference books.
A clinical study to evaluate the efficacy of Phala Taila Matra Basti in Kashtartava w.s.r. to Primary Dysmenorrhoea
Authors: Ashwini M  , Sharon Samuel
Published: May 2023

Background: Female health is a primary factor to be considered for the wellbeing and productivity of both family and society. Her menstrual health has a great impact on her educational, social and economic progress. Although dysmenorrhea is not life threatening, it is found to have a profound impact on daily activities resulting in absenteeism.[1] Primary dysmenorrhea prevalence estimates range from 25% to 90% among women and adolescents Studies from India reported the prevalence range between 50% to 87.8% During menstruation, many women experience gastrointestinal upsets which are increased by analgesics and anti-inflammatory drugs, which also cause headache, dizziness, drowsiness and blurred vision. The drugs in this Taila are Vatakaphahara, Shoolahara, Udararogahara, Srotovishodana, Garbhashaya Shodana, Balya. Due to these properties, it helps in reducing symptom of Kashtartava. Basti (therapeutic enema) is the ideal treatment option for disorders of Vata. Phala Taila[2] is a preparation mentioned in Kashyapa Samhita for management of aggravated Vata in Prusta (back of the body), Uru (hip), and Janga Pradesha (calf muscle). Aim: To analyse the effect of Phala Taila Matra Basti in the management of Kashtartava w.s.r to Primary Dysmenorrhoea. Method: “A Randomized controlled clinical study to evaluate the efficacy of Phala Taila Matrabasti in Kashtartava w.s.r to Primary Dysmenorrhoea.” Result: Taking all subjective and objective parameter into consideration especially with effect size comparison clearly shows that Group B is much better with respect to most of the parameter in providing clinical relief. Conclusion: Dashamoola Ksheera Yoga Basti is more effective than Phala Taila Matra Basti in the management of Kashartava w.s.r. to Primary Dysmenorrhoea.
Aromatherapy: A New Pragmatism in Dentistry [Part-1]
Authors: Supriya PR  , Nandan N  , Sunil Raj N  , Anitha C  , Soundarya Vishwanathan
Published: May 2023

One of the most rapidly expanding alternative medicine practises is aromatherapy, which combines massage, counselling, and a pleasant smell with the use of essential oils and aromatic plant compounds. Several clinical studies have already demonstrated the efficacy and usefulness of essential oils. Essential oils can help to reduce the number of pathogens in the mouth and assist in the action of antibiotics and other active components for the treatment of periodontitis, mucositis, and managing dental anxiety. This review will provide an overview of essential oils, including their therapeutic properties and applications.
Therapeutic aspects of Eranda Tail (Oil of Ricinus Communis)
Authors: Ramraj Singh  , Rupali Kakade  , Jayant Gulhane
Published: May 2023

Castor Oil is one of the main drugs used for Virechana Karma (purgative therapy) under Panchakarma therapy. Castor oil is a vegetable product extracted from Ricinus communis (castor seed). The castor oil is pungent; hot, heavy, and curative of Vata and Kapha. In combination with astringent, sweet, and bitter substances, it also, cures Pitta. It pacifies Vata, the aggravation of which is the root cause of all diseases. It is also administered as an adjuvant for various formulations. Even though it has various medicinal properties, inappropriate usage causes adverse effects such as dizziness, abdominal cramps, diarrhoea; etc. as well as a proper review of Eranda Tail w.s.r. to Samhita is not available. So, this article mainly focuses on the properties, qualities, Indication, Contraindication, Mode of action, administration, dose, and adverse effects of castor oil.
A review of Ayurvedic management of Sthaulya Vyadhi (Obesity)
Authors: Ramesh Prasad Gupta  , Prof. B.B. Khuntia
Published: May 2023

First line of treatment for any disease is Nidanasya Parivarjana. Sthaulya Chikitsa-Langhana (fasting), Langhana-Pachana (fasting and digestive drugs) and Doshavasechana (elimination) is considered as the line of treatment in Sthaulya. Sthaulya is a Santarpanottha Vyadhi and is best treated by Apatarpana and Langhana measures, which can be achieved by Shodhana as well as Shamana treatments. In conventional medicine, sedentary life style is the major cause of morbid accumulation of fat in the body leading to metabolic syndrome.
A conceptual view of Endometriosis through an Ayurveda Perspective
Authors: Neetu Singh  , Rashmi Sharma
Published: May 2023

Endometriosis is one of the most mysterious and fascinating benign gynecological disorders defined by implantation of functioning endometrial tissue outside the uterine cavity. The prevalence is about 10 percent. However, prevalence is high amongst the infertile women (30–40%) as based on diagnostic laparoscopy and laparotomy. It is estrogen dependent condition hence increases due to high estrogen level in the body and regression occurs during pregnancy & after menopause. Women with endometriosis are usually confronted with one or both of the two major problems- pain and infertility. Pain includes dysmenorrhea, dyspareunia, and chronic pelvic pain. In Ayurvedic it can be correlate with Vataja Yonivyapada on the basis of two symptoms dysmenorrhea and chronic pelvic pain. It can be correlate with different Yonivyapada on the basis of other symptoms. Ayurvedic management can be done on the basis of Tridoshic theory in which Vata is responsible for displacement of endometrial cells from their original location in the uterus to places outside the uterine cavity. Pitta responsible for involvement of blood, hormones, and menstruation as well as the inflammatory nature of the disease. Kapha responsible for increasing buildup of cells and overgrowing much like a tumor. So treatment approach can be Ampachana & correction of Agni, Vaatanulomana, Mridu Virechana, Vatashamaka, Raktasravarodhaka, Granthihar and Lekhan Chikitsa, etc. Life style and diet modifications are also to be advocated as their role in the establishment of any disease cannot be ignored.
Evaluation of Clinical Efficacy of Extrammune Tablet in Recurrent Upper Respiratory Tract Infections (URTI)
Authors: Shweta A. Sutar
Published: May 2023

Aim of the study: The objective of this clinical study was to evaluate the efficacy of Extrammune Tablets, a polyherbal preparation in recurrent URTI patients. Materials and Methods: A clinical trial was conducted on 60 patients, including both the sexes, and from   the age   group 10-60 years having low immunity and who were constantly suffering from various upper respiratory tract infections. The study drug was administered as 2 tablet twice a day for 3 months. Evaluation Parameters: 1) Incidence of participant-reported number of Infections (URTI- influenza-like syndrome). 2) Duration and severity of episodes. 3) Number of new antibiotics prescription for infections. Results: There was a statistically significant improvement in all the parameters evaluated. Conclusion: The above clinical trial shows that Extrammune tablet can be used to boost the immune system to fight against various infections especially upper respiratory tract infections.
Bibliometric review of publications related to Geriatric Care and Ayurveda
Authors: Singh Shyam B , Mansoria Poornima , Ahmad Azeem
Published: May 2023

Global population ageing presents an unprecedented set of problems, such as shifting disease burden, increasing health and long-term healthcare expenses, dissaving, and potential issues with old-age economic security. Ayurveda may provide some solutions for these issues because it already has a special division for treating elderly people. In the last few years, there has been research related to old age, in which Ayurveda has focused on the prevention and treatment of diseases occurring in old age. The analysis of this published work, journals, authors, organizations and keywords is done in this paper. 35 publications related to geriatric and Ayurveda published between 1999 and January 2023, were analyzed in various aspects and the conclusion was found that limited publications on geriatrics and Ayurveda care. These papers have been published in a total of 22 journals and 99 authors and 9 organizations were found related to these publications. The present paper presents a bibliometric review of the publications related to ageing and Ayurveda and emphasizes that research related to ageing Ayurveda should be encouraged.
A case study on Doshantha (Retinitis Pigmentosa) with Ayurvedic management
Authors: Arundhathi krishnan  , Rathi S.
Published: May 2023

Retinitis pigmentosa (RP) is a group of hereditary disorders of the photoreceptors and retinal pigment epithelium (RPE) which gradually causes night blindness and progressive constriction of the visual field. RP is a leading cause of visual disability, with a worldwide pre-valence of 1:4000. RP typically manifests with night blindness in adolescence, followed by concentric visual field loss, reflecting the principal dysfunction of rod photoreceptors; central vision loss occurs later in life due to cone dysfunction. Symptoms may become manifest during childhood or adulthood, and include poor night vision (nyctalopia) and constriction of peripheral vision (visual field loss).[1] In Ayurveda, the signs and symptoms of this can be compared with the Lakshanas of Doshandha. The present paper discusses a case of retinitis pigmentosa and its Ayurvedic treatment.
PERILAKU AUS DAN KOROSI LAPISAN BAJA TAHAN KARAT 420 DENGAN METODE ELECTRIC ARC SPRAY
Authors: Lusiani Rina , Munandar Aris , Listijorini Erny , Saefuloh Iman , Ula Shofiatul , Sunardi Sunardi
Published: May 2023

Thermal spray coating is a material protection process by depositing the coating material on the substrate material. Process parameters such as spray-off distance, surface roughness, and substrate preheat temperature, spray time, voltage, and arc current greatly influence the mechanical and tribological behavior. Selection of appropriate process parameters and coating materials must be carried out to obtain a coating that meets the design requirements. The coating method used is electric arc spray with parameters: spray-off distance of 200 mm, compressor air pressure of 7 bar, voltage of 32 volts, and layer thickness of 1 mm. At the same time, the independent variables are arc currents: 159, 185, and 299 amperes. The substrate material is AISI 1045 steel, PMET 885 intermediate material, and PMET 720 coating material. The tests carried out were observing the microstructure, hardness, wear rate, and corrosion rate. This research shows that the higher the arc current, the better the coating quality. At an arc current of 229 amperes, it is known that the hardness, the wear rate, and the corrosion rate are 398.10 VHN, 8.96 x 10-8 gram/mm2.s, and 0.8911 mpy, respectively. This research's contribution is to provide a reference on the influence of the arc current of the electrical arc spray coating process on the tribological behavior of the surface layer so that suitable for the desired application.
Practical Results of Computational and Experimental Investigations to Determine the Ranges of Change of the Main Controlled Parameters of Promising Aviation Complexes
Authors: Mukhin I. E. , Koptev D. S.
Published: May 2023

The purpose of research is to determine the list of necessary controlled parameters of promising aviation systems, which represent a complex system of interaction "pilot - aircraft - environment", as well as to assess the ranges of their change.

Methods. Research methods are based on the concepts of the theory of diagnostics and prognosis of the technical condition of aircraft, ergonomic systems. Methods of multi-criteria analysis, parametric and structural synthesis are used.

Results. It is shown that the choice of the range of controlled helicopter units is determined by their purpose, the severity of consequences in case of failure, testability, operating conditions and modes, the predicted level of reliability, as well as the experience of operating prototypes and analogues. A variant of organizing a parallel system for diagnosing and predicting the technical condition of advanced aviation systems has been developed. This article presents a stochastic (probabilistic) diagnostic model of damage to the inter-rotor bearing of an aircraft engine, designed to study the correlation dimension of a vibration signal, which imitates the spectral composition of a real vibration signal, with a different form of amplitude distribution density. A decisive rule for predicting engine failure 8-9 flights before the destruction of the inter-rotor bearing is presented.

Conclusion. For objective control of the parameters of units of heavy and light helicopters, they are divided into 10 groups, for each of which the composition of diagnostic control sensors is determined based on an analysis of the necessary and sufficient values of the parameters in real time. The range of measurements of specific physical quantities is assigned at the stage of designing one or another vital system of the aircraft. Limits of measurement of parameters are set during regular measurements, as well as at the stages of verification and testing of state control. A variant of the formation of a boundary separating a good and a faulty state, described by a hypersurface, is presented.
Líneas y variedades de algodón (Gossypium sp.) de fibra larga y extralarga para mercados de exportación. :resultados de la investigación en algodón, ensayos de rendimiento y pruebas regionales 2009 a 2011
Authors: Carrillo H. Carmen , Montenegro Ramos Omar , Barragán Quijano Eduardo , Cadena Torres Jorge , Mera Edward A.
Published: May 2023

El algodón es producido en el mundo por alrededor de 100 países, pero solamente un pequeño grupo de ellos concentra en gran parte la producción mundial. En los últimos años esta producción mundial alcanzó las 67,3 millones de toneladas, de las cuales el 75 % se concentró en 6 países, entre ellos China (27 %), Estados Unidos (18 %), India (11 %), Pakistán (9 %) y Brasil (5 %). Entre los países productores, Colombia ocupa el puesto 35, con una participación del 0,15 %.
Pengembangan teknologi tangki pintar sebagai sistem peringatan dini bencana kekeringan
Authors: Kurniawan Adhy , Setyawan Galih , Sembada Pratama Tirza Surya , Sabian Geradus Nieken
Published: May 2023

According to the National Disaster Management Agency, in 2021 there were 5,402 incidents recorded, one of them being drought disasters. During the drought, the availability of clean water was minimal, so clean water assistance came from other areas. The problem that is often encountered in the field is delays in water distribution assistance due to sudden information and the location of the aid is in areas that are difficult to reach. This research developed a water tank technology equipped with a sensor to provide information about water availability, the location of the tank placement to speed up information on dropping water in drought areas. This technology uses the NodeMCU ESP8266 module which functions as a microcontroller, to provide sensor-based information that detects the quantity and quality of water as well as the location of the tank. This system is based on the Internet of Things (IoT) and Blynk Android which makes it easier for people to get information in real time. The water availability indicator is presented in a three-color graphical display, namely green is a safe sign (sufficient water), yellow is a warning sign (water is reduced), and red is a sign that water availability is running low and it is necessary to drop clean water. Other information presented is water quality parameters such as pH, TDS, turbidity, and temperature as well as the location of the tank. This technology supports the achievement of SDGs, namely goals number 6 (clean water and proper sanitation) and 11 (sustainable cities and settlements).
Trade Liberalism-Capital Inflow: An Inclusive Framework for Zimbabwe
Authors: Mukoka Shame
Published: May 2023

This study sought to determine a framework of upholding trade liberalism for increased capital inflows in the form of Foreign Direct Investment (FDI) for Zimbabwe.  The study used the ARDL-ECM in the determination of the nexus between the two variables, for the data covering 1980 to 2021. Eviews Version 9.0 Statistical Package was used to run the regressions. Data were obtained from the Reserve Bank of Zimbabwe, International Monetary Fund and World Bank. The study found that in the short-run, trade openness has a significant inverse relationship with capital flows (FDI), whilst in the long-run there is a significant positive relationship between them for Zimbabwe. The study recommend that there be duty free on capital goods, that the government give incentives on exporters, that all goods exported go through the process of value addition, that the government provide subsidies on exporters and, that the government ensure efficiency at ports through infrastructure development.
СИНТЕЗ И ИЗУЧЕНИЕ СТРУКТУРЫ БИОАКТИВНЫХ НАНОЧАСТИЦ СИЛИКАТА МАГНИЯ
Authors: Маглакелидзе Д.Г. , Блинова А.А. , Шевченко И.М. , Тараванов М.А. , Колодкин М.А. , Облогин Я.А. , Жуковский Д.А.
Published: May 2023

В данной работе представлены результаты исследования биоактивных наночастиц силиката магния. Сами наночастицы получали методом химического осаждения в водной среде. Размер и форму образцов исследовали на ПЭМ-микроскопе. Установлено, что поверхность образцов представлена крупными агрегатами. В свою очередь, агрегаты состоят из сферических наночастиц силиката магния с размерами от 10 до 20 нм. На следующем этапе, с помощью нейросетевой обработки экспериментальных данных проводили оптимизацию синтеза наночастиц. Анализ полученной тернарной поверхности показал, что для получения образцов с наименьшим размером агрегатов (700 нм) параметрами синтеза являются: температура – 50 °С, скорость перемешивания – 600 об/мин, концентрация прекурсора – 0,5 моль/л. Определив оптимальные параметры синтеза силиката магния, проводили компьютерное квантово-химическое моделирование. В результате расчетов обнаружено, что энергия конфигурации составила E = –709,302 ккал/моль, величина химической жесткости η = 0,191 эВ, а мягкости – S = 2,62 эВ–1. На основе полученных данных можно заключить, что MgSiO3 обладает высокой стабильностью и характеризуется, как относительно мягкая молекула. На заключительном этапе работы образцы исследовали на ИК-спектрометре. Анализ ИК-спектра показал наличие характерных полос поглощения, которые соответствуют колебаниям связей в молекуле MgSiO3.