bluuebunny/crossref_metadata_2025 huggingface dataset:
The hidden cross talk between bone and tissues through bone turnover
Authors: González-Casaus María Luisa
Published: December 2023

Bone is more than a reservoir of calcium and phosphorus. Its lacuno-canalicular arrangement provides an important pathway for exchange with circulation and currently, the skeleton is considered a large endocrine organ with actions that go beyond the control of calcium-phosphorus balance mediated by fibroblastic growth factor 23 (FGF23). Parallel to the modulating effect of adipokines on bone turnover, certain bone proteins, such as osteocalcin and sclerostin, play a counter-regulatory role on energy metabolism, probably in an attempt to ensure its high energy requirement for bone turnover. In this crosstalk between bone and other tissues, especially with adipose tissue, canonical Wnt/β-catenin signaling is involved and therefore, sclerostin, an osteocyte derived protein that inhibits this signalling, emerges as a potential biomarker. Furthermore, its involvement in diverse pathologic conditions supports sclerostin as a therapeutic target, with an anti-sclerostin antibody recently approved in our country for the treatment of osteoporosis. This review addresses the endocrine nature of bone, the role of osteocalcin, and specially, the regulatory and modulatory role of sclerostin on bone turnover and energy homeostasis through its inhibitory effect on canonical Wnt/β-catenin signaling, as well as its potential utility as a biomarker.
Assessing clinical reasoning skills following a virtual patient dizziness curriculum
Authors: Kotwal Susrutha , Singh Amteshwar , Tackett Sean , Bery Anand K. , Omron Rodney , Gold Daniel , Newman-Toker David E. , Wright Scott M.
Published: December 2023

Objectives

Dizziness is a common medical symptom that is frequently misdiagnosed. While virtual patient (VP) education has been shown to improve diagnostic accuracy for dizziness as assessed by VPs, trainee performance has not been assessed on human subjects. The study aimed to assess whether internal medicine (IM) interns after training on a VP-based dizziness curriculum using a deliberate practice framework would demonstrate improved clinical reasoning when assessed in an objective structured clinical examination (OSCE).

Methods

All available interns volunteered and were randomized 2:1 to intervention (VP education) vs. control (standard clinical teaching) groups. This quasi-experimental study was conducted at one academic medical center from January to May 2021. Both groups completed pre-posttest VP case assessments (scored as correct diagnosis across six VP cases) and participated in an OSCE done 6 weeks later. The OSCEs were recorded and assessed using a rubric that was systematically developed and validated.

Results

Out of 21 available interns, 20 participated. Between intervention (n=13) and control (n=7), mean pretest VP diagnostic accuracy scores did not differ; the posttest VP scores improved for the intervention group (3.5 [SD 1.3] vs. 1.6 [SD 0.8], p=0.007). On the OSCE, the means scores were higher in the intervention (n=11) compared to control group (n=4) for physical exam (8.4 [SD 4.6] vs. 3.9 [SD 4.0], p=0.003) and total rubric score (43.4 [SD 12.2] vs. 32.6 [SD 11.3], p=0.04).

Conclusions

The VP-based dizziness curriculum resulted in improved diagnostic accuracy among IM interns with enhanced physical exam skills retained at 6 weeks post-intervention.
Relektüre ohne Rückkehr
Authors: Melters Benedikt
Published: December 2023

In his last work, Relire le relié, Michel Serres develops a philosophy of religion that circumvents the conventional demarcations of reason and faith, knowledge of the world and knowledge of revelation, or agnosticism and apology. In a structuralistically-informed relecture, he exposes the basic traits of religion. With its narratives and theologoumena, it captures and describes being-in-the-world as an event of universal synthesis. It is – in Serres’ diction – about the basic relatio of energy and information, entropy and negentropy, chaos and order. This relié is described neither as an effort or act of a subject, a system, a language community, nor sufficiently as an emergence effect of evolutionary-natural processes. The recording of this synthesis forbids both any dichotomy of an irresolvable hiatus as well as the construction of a unitary space of any kind.
University researcher-instructor partnership: Co-learning of trans/plurilingual pedagogies for critical language awareness in French L2/Lx classrooms
Authors: Lau Sunny Man Chu , Théberge Sarah , Dault Caroline
Published: December 2023

Drawing on trans/plurilingual approaches, this paper describes a collaborative action research project between an education researcher and two university instructors of French as a second or other language (L2/Lx) in Quebec, Canada to explore holistic and dynamic ways of L2/Lx education for critical language and cultural awareness. Valuing research as praxis, we examine our three-year interdisciplinary collaboration processes, describing how our various research expertise and theoretical orientations as well as our language learning and professional experiences shaped and facilitated our research partnership. Through vignettes from our professional learning community, we each articulate in our own voice the co-learning processes with one another and with students. Using the lenses of co-stance, co-designs, and co-shifts (Tian and Shepard-Carey 2020. (Re)imagining the future of translanguaging pedagogies in TESOL through teacher–researcher collaboration. Tesol Quarterly 54(4). 1131–1143), we captured moments of our emerging nuanced understanding of what and how trans/plurilingual practices supported more in-depth French learning and critical language awareness. As we translanguaged using a mix of English, French, and other languages, we also found ourselves constantly re/trans-languaging our disciplinary expertise and theoretical framings to negotiate our co-stances and practices. Through these transknowledging processes (Heugh 2021. Southern multilingualisms, translanguaging and transknowledging in inclusive and sustainable education. In Philip Harding-Esch & Hywel Coleman (eds.), Language and the sustainable development goals: Selected proceedings of the 12th Language and Development Conference, 37–47. Dakar, Senegal: British Council), we engaged in translingual reflexivity and expanded each other’s fields of vision, supporting more critical reflections and careful listening for transformative change.
Celastrol inhibits angiogenesis and the biological processes of MDA-MB-231 cells via the DEGS1/S1P signaling pathway
Authors: Jia Lulu , Zhu Shengnan , Zhu Mingfei , Nie Rongrong , Huang Lingyue , Xu Siyuan , Luo Yuqin , Su Huazhen , Huang Shaoyuan , Tan Qinyou
Published: December 2023

Celastrol (Cel) shows potent antitumor activity in various experimental models. This study examined the relationship between Cel’s antivascular and antitumor effects and sphingolipids. CCK-8 assay, transwell assay, Matrigel, PCR-array/RT-PCR/western blotting/immunohistochemistry assay, ELISA and HE staining were used to detect cell proliferation, migration and invasion, adhesion and angiogenesis, mRNA and protein expression, S1P production and tumor morphology. The results showed that Cel could inhibit proliferation, migration or invasion, adhesion and angiogenesis of human umbilical vein endothelial cells (HUVECs) and MDA-MB-231 cells by downregulating the expression of degenerative spermatocyte homolog 1 (DEGS1). Transfection experiments showed that downregulation of DEGS1 inhibited the above processes and sphingosine-1-phosphate (S1P) production of HUVECs and MDA-MB-231 cells, while upregulation of DEGS1 had the opposite effects. Coculture experiments showed that HUVECs could promote proliferation, migration and invasion of MDA-MB-231 cells through S1P/sphingosine-1-phosphate receptor (S1PR) signaling pathway, while Cel inhibited these processes in MDA-MB-231 cells induced by HUVECs. Animal experiments showed that Cel could inhibit tumor growth in nude mice. Western blotting, immunohistochemistry and ELISA assay showed that Cel downregulated the expression of DEGS1, CD146, S1PR1-3 and S1P production. These data confirm that DEGS1/S1P signaling pathway may be related to the antivascular and antitumor effects of cel.
Application of Artificial Intelligence or machine learning in risk sharing agreements for pharmacotherapy risk management
Authors: Oborotov Grigory A. , Koshechkin Konstantin A. , Orlov Yuriy L.
Published: December 2023

Applications of Artificial Intelligence in medical informatics solutions risk sharing have social value. At a time of ever-increasing cost for the provision of medicines to citizens, there is a need to restrain the growth of health care costs. The search for computer technologies to stop or slow down the growth of costs acquires a new very important and significant meaning. We discussed the two information technologies in pharmacotherapy and the possibility of combining and sharing them, namely the combination of risk-sharing agreements and Machine Learning, which was made possible by the development of Artificial Intelligence (AI). Neural networks could be used to predict the outcome to reduce the risk factors for treatment. AI-based data processing automation technologies could be also used for risk-sharing agreements automation.
Enhancing high-speed networks using RGB-based WLAN through Ro-FSO integration in the 5 GHz band
Authors: Sharma Abhishek , Mishra Vivekanand
Published: December 2023

The limited bandwidth constraints imposed by conventional wireless carriers pose a significant hurdle when it comes to the delivery of high-speed broadband services. In response to this challenge, Radio over Free Space Optics (Ro-FSO) has emerged as a viable and innovative solution, seamlessly amalgamating wireless and optical systems. This integration proves particularly invaluable in sensitive environments, such as hospitals, where the risk of electromagnetic interference disrupting critical medical equipment is a real concern. Ro-FSO offers a disruption-free avenue for high-speed data transmission, positioning it as the ideal choice for broadband services, including Wireless Local Area Networks (WLANs). Within the scope of this study, we introduce a high-speed Ro-FSO link, showcasing the capability to concurrently transmit three independent channels with Red, Green and Blue (RGB) laser respectively, each supporting a robust 1 Gbps data rate. These data streams are skilfully up-converted to the 5 GHz RF bands, encompassing transmission distances of 650 m across the FSO channel. Our numerical simulation findings underscore the successful transmission of all the channels using wavelength division multiplexing (WDM), seamlessly meeting the prescribed Bit Error Rate (BER) and eye pattern criteria, solidifying the Ro-FSO’s standing as a promising solution for high-speed broadband delivery.
Vollzugsöffnende Maßnahmen und Entlassungsvorbereitung – Gesetzgebung und Praxis in den Bundesländern
Authors: Dünkel Frieder , Harrendorf Stefan , Geng Bernd , Pruin Ineke , Beresnatzki Paul , Treig Judith
Published: December 2023

Der Beitrag behandelt die rechtliche und rechtstatsächliche Entwicklung vollzugsöffnender Maßnahmen in Deutschland im Vergleich der Bundesländer. Als vollzugsöffnende Maßnahmen werden hier vor allem die Verlegung in den offenen Vollzug, Ausgang, Langzeitausgang (regelmäßig 2–3 Tage) und Freigang, d. h. das regelmäßige Verlassen der Anstalt, um einer Arbeit oder Ausbildungsmaßnahme nachzugehen, zudem aber auch Ausführung und Außenbeschäftigung angesehen. Die Rechtslage unterscheidet sich angesichts der seit 2006 erlassenen Länderstrafvollzugsgesetze in einigen Detailfragen erheblich mit Blick auf ein mehr oder weniger stark öffnungsorientiertes Vollzugsregime. Die Praxis divergiert im Bundesländervergleich anhand der in den Ländern erstellten Statistiken. In Berlin und Nordrhein-Westfalen befinden sich stichtagsbezogen ca. 6–10-mal so viele Gefangene im offenen Vollzug wie in Bayern, Hessen, Sachsen, Sachsen-Anhalt oder Thüringen. Ähnliche Unterschiede finden sich bei den Vollzugslockerungen, wo die Stadtstaaten Berlin, Bremen, Hamburg und Nordrhein-Westfalen sehr viel stärker von überleitungsorientierten Maßnahmen Gebrauch machen als die südlichen Bundesländer in Ost- und Westdeutschland. Weitere Details wie z. B. die während der Corona-Pandemie in unterschiedlichem Ausmaß rückläufigen Lockerungszahlen werden erörtert. Insgesamt zeigen sich einige Defizite und unausgeschöpfte Potenziale eines überleitungsorientierten Vollzugs, von dem offensichtlich nur ein Teil der Gefangenen profitiert. Dabei zeigt sich, dass eine »liberalere« lockerungsfreundliche Vollzugspraxis nicht zu einer Einbuße an Sicherheit für die Allgemeinheit führt, indem Gefangene Lockerungen missbrauchen.
Electromagnetic signal propagation through lossy media via surface electromagnetic waves
Authors: Smolyaninov Igor I. , Balzano Quirino , Smolyaninova Vera N. , Soloviova Daryna
Published: December 2023

A theory of surface electromagnetic waves in gradient media exhibiting arbitrary surface gradients of dielectric permittivity and magnetic permeability has been developed. Novel low-loss propagating surface wave solutions have been found in the gradient media in which both dielectric permittivity and magnetic permeability are dominated by their imaginary parts. Several examples of gradient geometries in which the surface wave problem may be solved analytically have been found. Examples of practically useful surface wave geometries spanning from radio communication underwater to UV nanophotonics have been demonstrated.
Energy bandgap and thermal characteristics of non-Darcian MHD rotating hybridity nanofluid thin film flow: Nanotechnology application
Authors: Eid Mohamed R. , Jamshed Wasim , Abd-Elmonem Assmaa , Al-Hossainy Ahmed F. , Almutlaq Nasser , Amjad Ayesha , El Din Sayed M.
Published: December 2023

The primary purpose of this research is to examine how the presence of thermal features variation affects the velocity and heat transfer rate of nanofluids composed of sodium alginate and molybdenum disulfide [Na-Alg/MoS2]m and sodium alginate and molybdenum disulfide and graphene oxide [Na-Alg/MoS2 + GO]h, respectively, flowing between two rotating, permeable plates. Both centripetal and Coriolis forces, which act on a spinning fluid, are taken into account. The impacts of magnetized force, thermal radiative flux, heat source (sinking), and varied pressure in the Darcy–Forccheimer material are considered. Using the physical vapor deposition method, single and hybridity nanofluid thin films of thickness 150 ± 5 nm may be created. The controlling mathematical equations of the suggested model are solved using the Keller-box technique in MATLAB software. The surface friction coefficient of a hybrid nanofluid is less, and the heat transfer rate is greater than that of a regular nanofluid. The rate of heat transmission is slowed by the rotational parameter. The thermal efficiency of mono nanofluids is as low as 6.16% and as high as 21.88% when compared to those of hybrid nanofluids. In particular, the findings of density functional theory (DFT) calculations reveal that the energy bandgap

Δ

E

g

Opt

\Delta {E}_{{\rm{g}}}^{{\rm{Opt}}}

drops from 1.641 eV for conventional nanofluid to 0.185 eV for hybridity nanofluid. Based on the findings, the addition of graphene oxide nanoparticles to the base nanofluid converts it from a semi-conductor to a hybridity nanofluid as a superconductor.
HR GRS-HPGe as NDT method for quantification of uranium and 235U content in process stream samples from UO2 fuel production facilities
Authors: Rao Yarasi Balaji , Ray Vinod K. , Kumar Putta V. Nagendra , Srivastava Dinesh
Published: December 2023

Uranium concentration and uranium isotopic content are two important and critical parameters for any nuclear fuel fabrication facilities. In the present study emphasis has been given on the usage of high resolution gamma ray spectrometric (HR-GRS) technique with HPGe detector for the determination of uranium and 235U content in uranium process stream samples. The work has been carried out with an aim to give quick analytical feedback to production facility and also to minimize the generation of analytical waste. These are important requirements for any industrial lab with high analytical load attached to production facility. In this paper a simple and a non-destructive testing (NDT) method has been described for quantification of uranium and 235U content in samples received from UO2 fuel production facilities using HR-GRS technique with high purity germanium (HPGe) detector. A 185.7 keV line of 235U has been used for quantification of uranium in process solutions containing 1  g/L to 600 g/L of uranium covering both aqueous and organic process stream solutions. The results have been compared with that of Davies and Gray method. The limitations associated with gamma ray emitted from daughter products of 238U and self-induced or self-excited X-ray fluorescence lines of uranium have also been studied. Multi Group Analysis of Uranium (MGAU) software code has been used for measurement of 235U content in variety of samples. The results obtained are compared with that of results by thermal ionization mass spectrometer (TIMS).
When is the allele-sharing dissimilarity between two populations exceeded by the allele-sharing dissimilarity of a population with itself?
Authors: Liu Xiran , Ahsan Zarif , Martheswaran Tarun K. , Rosenberg Noah A.
Published: December 2023

Allele-sharing statistics for a genetic locus measure the dissimilarity between two populations as a mean of the dissimilarity between random pairs of individuals, one from each population. Owing to within-population variation in genotype, allele-sharing dissimilarities can have the property that they have a nonzero value when computed between a population and itself. We consider the mathematical properties of allele-sharing dissimilarities in a pair of populations, treating the allele frequencies in the two populations parametrically. Examining two formulations of allele-sharing dissimilarity, we obtain the distributions of within-population and between-population dissimilarities for pairs of individuals. We then mathematically explore the scenarios in which, for certain allele-frequency distributions, the within-population dissimilarity – the mean dissimilarity between randomly chosen members of a population – can exceed the dissimilarity between two populations. Such scenarios assist in explaining observations in population-genetic data that members of a population can be empirically more genetically dissimilar from each other on average than they are from members of another population. For a population pair, however, the mathematical analysis finds that at least one of the two populations always possesses smaller within-population dissimilarity than the value of the between-population dissimilarity. We illustrate the mathematical results with an application to human population-genetic data.
Machine Learning-Derived Active Sleep as an Early Predictor of White Matter Development in Preterm Infants
Authors: Wang Xiaowan , de Groot Eline R. , Tataranno Maria Luisa , van Baar Anneloes , Lammertink Femke , Alderliesten Thomas , Long Xi , Benders Manon J. N. L. , Dudink Jeroen
Published: December 2023

White matter dysmaturation is commonly seen in preterm infants admitted to the neonatal intensive care unit (NICU). Animal research has shown that active sleep is essential for early brain plasticity. This study aimed to determine the potential of active sleep as an early predictor for subsequent white matter development in preterm infants. Using heart and respiratory rates routinely monitored in the NICU, we developed a machine learning-based automated sleep stage classifier in a cohort of 25 preterm infants (12 females). The automated classifier was subsequently applied to a study cohort of 58 preterm infants (31 females) to extract active sleep percentage over 5–7 consecutive days during 29–32 weeks of postmenstrual age. Each of the 58 infants underwent high-quality T2-weighted magnetic resonance brain imaging at term-equivalent age, which was used to measure the total white matter volume. The association between active sleep percentage and white matter volume was examined using a multiple linear regression model adjusted for potential confounders. Using the automated classifier with a superior sleep classification performance [mean area under the receiver operating characteristic curve (AUROC) = 0.87, 95% CI 0.83–0.92], we found that a higher active sleep percentage during the preterm period was significantly associated with an increased white matter volume at term-equivalent age [β = 0.31, 95% CI 0.09–0.53, false discovery rate (FDR)-adjustedp-value = 0.021]. Our results extend the positive association between active sleep and early brain development found in animal research to human preterm infants and emphasize the potential benefit of sleep preservation in the NICU setting.
Endometriosis, polycystic ovary syndrome, and the thyroid: a review
Authors: Kirkegaard Signe , Uldall Torp Nanna Maria , Andersen Stig , Andersen Stine Linding
Published: December 2023

Endometriosis and polycystic ovary syndrome (PCOS) are common gynecological disorders that constitute a significant burden of disease in women of fertile age. The disorders share a link to female reproduction and infertility; however, divergent effects on menstrual cycle, related hormones, and body composition have been proposed. Disorders of the thyroid gland including abnormal thyroid dysfunction (hyperthyroidism or hypothyroidism) and/or markers of thyroid autoimmunity similarly show a female predominance and onset in younger age groups. We reviewed the literature on the association between endometriosis, PCOS, and thyroid disease up until July 1, 2023, and identified 8 original studies on endometriosis and thyroid disease and 30 original studies on PCOS and thyroid disease. The studies were observational and heterogeneous regarding the design, sample size, and definitions of exposure and outcome; however, a tendency was seen toward an association between hyperthyroidism and endometriosis. Especially an association between endometriosis and slightly elevated levels of thyroid-stimulating hormone receptor antibodies has been found and corroborated in studies from different populations. On the other hand, the literature review turned a focus toward an association between hypothyroidism and PCOS, however, with uncertainties as to whether the association is caused by hypothyroidism per se and/or the thyroid autoantibodies (thyroid peroxidase and thyroglobulin antibodies). More evidence is needed to substantiate an association between endometriosis, PCOS, and thyroid disease, and to differentiate between the role of thyroid function and thyroid autoimmunity. Furthermore, studies are warranted to extend knowledge on the different disease characteristics and underlying mechanisms.
Comparisons of clinical outcomes between newly diagnosed early- and late-onset T2DM: a real-world study from the Shanghai Hospital Link Database
Authors: Tao Xinge , Xue Yanbin , Niu Rui , Lu Wenjing , Yao Huayan , He Chunmei , Cui Bin , Liu Changqin
Published: December 2023

Objective

The aim of this study was to compare the differences in incident population, comorbidities, and glucose-lowering drug prescriptions between newly diagnosed patients with early-onset type 2 diabetes mellitus (T2DM) and those with late-onset T2DM to provide real-world evidence for clinical practice.

Methods

This study was based on the Shanghai Hospital Link Database (SHLD). Anonymized electronic medical record (EHR) data from 2013 to 2021 were included in this study. Newly diagnosed patients with T2DM were defined as those without related diagnostic records or glucose-lowering medicine prescriptions in the past 3 years. Early-onset T2DM was defined as patients who were aged 18–40 years old at the first visit for T2DM to represent those who were born after the 1980s. And late-onset T2DM was defined as those aged 65–80 years old to represent those who were born in a relatively undeveloped period. Descriptive statistical analyses were performed to describe their incidence number, glucose-lowering drug prescriptions, and comorbidities at the first visit to the hospital between two T2DM groups.

Results

There were a total of 35,457 newly diagnosed patients with early-onset T2DM and 149,108 newly diagnosed patients with late-onset T2DM included in this study. Patients with late-onset T2DM constituted the majority and their number increased by 2.5% on average by years, while the number of patients with early-onset T2DM remained stable each year. Compared with late-onset T2DM patients, more early-onset T2DM patients had dyslipidemia at the first visit to hospitals (9.5% vs 7.7%, P < 0.01) despite their significant age differences. Patients with early-onset T2DM were more likely to use metformin (74.8% vs 46.5, P < 0.01), dipeptidyl peptidase-4 inhibitors (DDP-4i) (16.7% vs 11.2%, P < 0.01), thiazolidinediones (TZD) (14.9% vs 8.4%, P < 0.01), sodium glucose cotransporter 2 inhibitors (SGLT2-i) (0.8% vs 0.3%, P < 0.01), and glucagon-like peptide 1 receptor agonists (GLP-1 RA) (3.7% vs 0.5%, P < 0.01) at their first visit to the hospital.

Conclusions

Different characteristics were observed between patients with early-onset T2DM and those with late-onset T2DM. Compared with patients with late-onset T2DM, those with early-onset T2DM were more prone to dyslipidemia and had novel organ-protective drugs prescribed.
LITERATURA Y EDUCACIÓN EN VALORES. EL PROBLEMA DE LA UTILIZACIÓN DE LA OBRA LITERARIA COMO INSTRUMENTO
Authors: Rodríguez Gutiérrez Borja , Gutiérrez Sebastián Raquel
Published: December 2023

Ante la evidencia de la utilización de las obras literarias como medio de enseñanza de valores, el artículo reflexiona sobre esta realidad. Tiene en cuenta la diferencia de considerar las obras desde un punto de vista estrictamente positivista o desde la estética de la recepción. Continúa desarrollando la idea de que la estética de la recepción se hizo necesaria, precisamente, ante la pérdida de referencia de los valores inherentes a la obra. Desarrolla los conceptos de la estética de la recepción que hacen referencia al lector y se pregunta finalmente hasta qué punto se puede llegar en la utilización de la obra literaria y si es legítimo, para conseguir los fines didácticos, dejar al lector sin libertad de elección y crítica.
LA INTEGRACIÓN ENTRE EL CONOCIMIENTO DISCIPLINAR Y EL CONOCIMIENTO PEDAGÓGICO EN LA FORMACIÓN DE PROFESORES Y LA CONTRIBUCIÓN DE LA TEORÍA DE LA ENSEÑANZA DE VASILI DAVÍDOV
Authors: Libâneo José Carlos
Published: December 2023

El texto aborda el tema de la formación docente en el marco de la internacionalización de las políticaseducativas que imponen unas directrices referidas al curriculum y a su influencia en la formación y aactuación profesional de los docentes. Se pone demanifiesto la necesidad de planificar y orientar laformación profesional para una educación más humana y crítica. Una de las cuestiones más sensibles delos planteamientos curriculares es la disociación entre el conocimiento pedagógico y conocimientodisciplinario, realizándose una separación entre la didáctica, la epistemología de las disciplinas ymetodologías de enseñanza. Una visión histórica sobre el desarrollo de la didáctica y didácticasdisciplinares y la relación entre la formación en contenidosespecíficos y la formación pedagógica, obliga aargumentar en favor de la necesaria integración entre la didáctica y la epistemología de las disciplinas,estableciendo interconexiones entre la formación disciplinar y la formación pedagógica. El texto abordapautas para profundizar en el contenido de la didáctica desde la perspectiva de la teoría de la enseñanzadesarrollante de Vasili Davydov. Se señala las relaciones necesarias entre la estructura epistemológica dela ciencia de referencia, el planteamiento psicopedagógico del aprendizajes y el plan de las prácticassocio-culturales e institucionales, tanto para repensar la concepción y el diseño de la formación deprofesores como para orientar la planificación y conducción del proceso de enseñanza-aprendizaje.
PROPUESTA METODOLÓGICA PARA EL USO DE LAS FUENTES HISTÓRICAS DEMOGRÁFICAS DE LA EDAD MODERNA COMO RECURSO DIDÁCTICO
Authors: García-Morís Roberto
Published: December 2023

En esta aportación se presenta una propuesta metodológica para el trabajo con fuentes históricas en el Bachillerato. Más concretamente dentro del área de Historia, se propone el trabajo con algunas de las fuentes históricas propias de la investigación en Historia Moderna, desde el ámbito demográfico. La finalidad de la aportación no es otra que familiarizar al discente con el material utilizado por el historiador para la construcción del pasado, a fin de promover la visión del carácter científico de la disciplina y del proceso de reconstrucción histórica.
APORTACIONES DE LA NEUROCIENCIA COGNITIVA A LA ESTIMULACIÓN AUDITIVA MUSICAL DE 0 A 6 AÑOS.
Authors: Botella Nicolás Ana María , Peiró Esteve María de los Ángeles
Published: December 2023

Este artículo forma parte de una investigación más amplia acerca de la actitud y la aptitud que los maestros generalistas de 2º ciclo de Educación Infantil de los colegios públicos de Valencia tienen para estimular auditivamente a sus alumnos a partir de la discriminación auditiva y la escucha comprensiva de las audiciones musicales, con el fin de desarrollar el oído interno y la capacidad atencional. A lo largo de este trabajo se explica cómo afecta al cerebro infantil una continua estimulación sensorial, concretamente la auditiva, desde el ámbito neurológico.
CONSUMO DE FRUTAS E VERDURAS DE ESTUDANTES DE EDUCAÇÃO BÁSICA
Authors: Da Rosa Piasetzki Cláudia Thomé , De Oliveira Boff Eva Teresinha , Jimenez-Ridruejo Guillermo
Published: December 2023

Cada sociedade desenvolve os hábitos alimentares de seus indivíduos de acordo com a cultura e condições de sua realidade vivencial. Esta pesquisa buscou identificar e compreender os hábitos alimentares/consumo de frutas e verduras de estudantes de educação básica. Foram analisadas as respostas de 351 estudantes, de três escolas do Brasil e três da Espanha, de um questionário contendo 23 questões. As populações estudadas são similares em idade, distribuição por sexo e escolaridade. Semelhanças foram encontradas mediante a deficiência no consumo de frutas e verduras. Consideramos isto um fator limitante em ambos os países para nutrição adequada.
INCIDENCIA DEL APRENDIZAJE COLABORATIVO EN LA PRÁCTICA EDUCATIVA
Authors: Peñaloza Janine Coromoto
Published: December 2023

La presente investigación tuvo como objeto de estudio al trabajo colaborativo el cual constituye un aporte a la transformación del proceso de enseñanza y del proceso de aprendizaje, con la convicción de que a través de la socialización se puede construir el conocimiento desde una visión pluridimensional y donde a través del diálogo se pueden generar  aportes y soluciones sobre diferentes áreas del contenido académico. Viene a promover diversos aspectos  como: fortalecer las relaciones sociales, fomentar los valores de respeto, solidaridad, tolerancia entre otros; incentivar el pensamiento creativo, participativo, crítico y reflexivo. Sirviendo como foco de luz en el transitar del proceso educativo, y  camino mediador entre todos sus  actores, haciendo uso efectivo de las herramientas tecnológicas como recurso esencial requerido por la sociedad del conocimiento y de la información. Permitió concluir que incentivar la relación de la dinámica grupal, fortaleciendo las relaciones interpersonales entre todos los estudiantes, evitando el sectarismo y discriminación que pudiese ocurrir por parte de ellos dentro del ambiente de clase, permitiendo así que mejore el clima siendo más entusiasta y agradable. Vincular la tecnología de la información y la comunicación (tic`s) en el proceso educativo de forma acomodaticia, ayudando convertir  una herramienta que muchas veces es  “distractora” en una herramienta “formadora”. Todo bajo la astucia del docente en conseguir que su vinculación sea favorable, lo que generaría un ambiente de trabajo más dinámico y efectivo, desarrollando habilidades de búsqueda, análisis, organización y decisión en la aplicabilidad de la información para facilitar, así su comprensión.
DO DIREITO À APRENDIZAGEM: PERSPECTIVAS TEÓRICAS E DECORRÊNCIAS PARA A PRÁXIS EDUCATIVA NA EDUCAÇÃO BÁSICA
Authors: Menegat Jardelino , Lindemann Júlio César , Meira Seniw Rafael
Published: December 2023

El texto es el resultado de una investigación descriptiva y documental. Presenta un análisis de los propósitos y objetivos de la educación básica, identificando las perspectivas teóricas subyacentes y sus consecuencias para la práctica educativa en relación a la enseñanza-aprendizaje. Los presupuestos teóricos se seleccionaron en base a los temas emergentes del análisis documental de los dispositivos legales, derivados de la utilización de la técnica de análisis de contenido. El pleno desarrollo del alumno; la formación de valores y actitudes; el pensamiento crítico y la autonomía intelectual, a través del desarrollo de la capacidad de aprender a lo largo de la vida; la comprensión de las bases científicas y tecnológicas de los procesos de producción; la preparación básica para el trabajo y educar a los ciudadanos están enfatizadas en las dimensiones que se incluirán en los procesos de enseñanza-aprendizaje.
EMPLEO DE LA FOTOGRAFÍA PARA DESARROLLAR LA ALFABETIZACIÓN MULTIMODAL. PROPUESTA DE ANÁLISIS
Authors: Mendioroz Lacambra Ana María , Asiáin Ansorena Alfredo
Published: December 2023

La construcción social de significados se vehicula con mensajes que combinan sistemas semióticos multimodales, y que en su recorrido transmedial se resignifican. Planteamos una propuesta de lectura de fotografías en contextos físicos y en recorridos transmedia, desde la semiótica cultural y el Análisis del Discurso Multimodal. Las lecturas de dos fotografías realizadas por el productor y los investigadores, han permitido elaborar el instrumento que será implementado entre los productores de significado, en la siguiente fase investigativa. Su evaluación servirá para delimitar las cuestiones básicas que facilitan el desarrollo de la alfabetización multimodal, digital y crítica, objetivo principal del trabajo. Las primeras conclusiones apuntan a una necesidad formativa sobre la dimensión relacional y los procesos inferenciales de evaluación, apreciación y recreación
MULTICULTURALISMO Y LITERACIDAD VISUAL: ANÁLISIS DE LAS NARRATIVAS HISTÓRICAS DEL PROFESORADO DE PRIMARIA EN FORMACIÓN
Authors: Medina Quintana Silvia , García-Morís Roberto
Published: December 2023

Este estudio pertenece a una línea de investigación sobre literacidad visual y en él se analizan las narrativas históricas que estudiantes de tercero de Grado de Primaria de la Universidad de Córdoba construyen a partir del análisis de una fotografía de una calle de una ciudad de Nepal, teniendo en cuenta la perspectiva multicultural. El análisis muestra que este grupo de estudiantes arroja una visión eurocéntrica sobre la misma, fijándose en aspectos cotidianos en su día a día extrapolados a esa realidad distinta y realizando valoraciones sobre la situación socioeconómica del país. Resulta fundamental trabajar con los futuros docentes la empatía con otras sociedades y la idea de alteridad para que fomenten este tipo de actitudes en su práctica docente.
UN VIAJE EN EL TIEMPO POR LA ALFABETIZACIÓN CIENTÍFICA EN ESPAÑA
Authors: Pérez Martín José Manuel
Published: December 2023

En los últimos años, la enseñanza de las ciencias se ha encaminado hacia un enfoque integrado de los saberes y sus aplicaciones en la vida cotidiana que se ha denominado STE(A)M (del inglés Science, Technology, Engineering, Arts, and Mathematics). El objetivo de este trabajo fue analizar la evolución histórica de la enseñanza de las ciencias en España, a través de los manuales escolares del fondo bibliográfico el Museo Pedagógico Jesús Asensi que se datan hasta de finales del s. XIX. Los resultados de nuestro estudio demuestran que, en la educación científica en España, existe una tendencia histórica hacia la integración de las ciencias con la vida real hasta 1935, aunque sin alcanzar enfoques STE(A)M
Study on bearing capacity of LVL asymmetric truss of lightweight poplar wood
Authors: Wan Zeqing , Zhang Yu , Liu Yan , Fang Xiuyuan , Gong Meng
Published: December 2023

Compared with natural wood, laminated veneer lumber has the characteristics of high strength, flexible specifications, excellent stability, and good economy. In order to study the bearing capacity of LVL trusses, the mechanical properties of LVL materials were tested. The static load test was carried out by using 3 pieces of LVL truss, and the load-deflection relationship, load-strain relationship, bearing capacity and failure mode of LVL trusses were studied. Based on the simplified joint analysis method, the metal plate connection and bolted truss were analyzed, and the bearing capacity calculation formula was developed. The results show that the upper chord instability is the main failure mode for large-span light LVL truss. A simplified formula for bearing capacity of LVL truss was proposed, and the predicted results were in good agreement with the experimental results. Finally, an application example of LVL truss engineering design and construction is briefly introduced. The research can provide technical support for the promotion and application of LVL truss of lightweight poplar wood.
Sensory and Oxidative Stability of Roasted Peanuts Coated with Arabic Gum and A Synthetic Antioxidant During Storage
Authors: Aljaludi Rawan , Alkhderat Razan , Al-Dabbas Maher
Published: December 2023

The impact of coating formulations containing Arabic gum (AG) and Arabic gum with 100 ppm BHT on the oxidative stability and sensory attributes of roasted peanuts during a 120-day storage period at room temperature (RT) was investigated and compared to roasted, uncoated peanuts (control). The oxidative stability of raw peanuts (P), roasted peanuts (RP), roasted and coated peanuts with Arabic gum (RCP-AG), and roasted and coated peanuts with Arabic gum and 100 ppm BHT (RCP-AG-BHT) was determined based on parameters such as free fatty acids percentage (FFA%), peroxide value (PV), p-Anisidine value (pAV), Totox value (TV), and sensory properties at intervals of 0, 30, 60, and 120 days.The estimated coating percentage (CP %) for all treatments is about 2.5% and the yield of oil from hydraulic pressed peanuts kernels and treatments were ranged from 35.6 to 47.1%. Nine fatty acids were identified from raw and roasted peanuts oil and characterized by large percentage of unsaturated fatty acids (USFAs) (82.1 %) with large proportion of oleic acid (49.45%) and linoleic acid (31.92%), while saturated fatty acids were 17.9%, with large proportion of palmitic acid (11.36%) followed by stearic acid (3.48%) in RP. The FFA (%) of extracted raw peanuts oil was 0.68%, this percentage was increased after roasting significantly (p< 0.05) in all treatments and control, but it didn't increase during storage period. An increase in PV values of roasted and treated samples were noticed throughout the storage time. After 4 months of storage, the maximum value of PV was (75.1 meq/kg) recorded by the roasted sample (RP), whereas the minimum value was (43.9 meq/kg) recorded by (RCP-AG- BHT). pAV increased significantly after roasting and during storage time in all peanuts samples. However, RP-AG-BHT showed no significant differences in pAV after one month of storage. An increase in TV values of roasted and treated samples were noticed throughout the storage time, while the TV for RP-AG and RP-AG-BHT where less when compared with the control (RP). There were no significant differences (P < 0.05) in the color, hardness and crunchiness between control and treatments after 2 months of storage. However, Glossiness, rancidity and off-flavor were significantly affected.
A classical ancient polis: the power-holding group and the features of exchange and appropriation
Authors:   Ukraine State University of Science and Technology (Dnipro), Tarasevych Viktor , Lebedieva Valentyna ,   Ukraine State University of Science and Technology (Dnipro)
Published: December 2023

The article continues the series of publications about the universum evolution of the Ancient Greek sub civilization of the Antique civilization and is devoted to the characteristics of the structure of the power-holding group, the exchange of its essential forces for those of the polis civil community, as well as the struggle of its actors for the appropriation of the centralized excess, surplus and necessary product and the corresponding contradictions. The rise and development of polis democracy allowed the inclusion of representatives of various social clusters and actors of various forms of appropriation in the permanent composition of the power-holding group, and a significant complication of the latter’s composition and structure. The power-holding group becomes an aggregated actor of the mixed social-individual appropriation, and the interaction of the corresponding forms of object appropriation mainly corresponds to the complex network interconnections between this group’s traditional, socio-economic and functional sub-actors. The role of primary driving force in the evolution of the power-holding group is performed by the contradictions between its socio-economic sub-actors, whose transformed form are the contradictions between functional sub-actors. The use of the potential of the labor theory of value and the general theory of value makes it possible to define the conditions and contents of the equivalent and non-equivalent exchange of humanized and objectified essential forces between the power-holding group and the civil community in the polis, as well as the general public, synergistic public, power-proprietary and exploitative components of the centralized excess, surplus and necessary product. Despite the obvious progress, the power-holding group failed to achieve a level of complexity and self-organization adequate to the existing civil community of the polis, since the effectiveness of the mechanisms of realization of general public and synergistic public interests was inferior to that of the realization of private, clan and corporate interests.
Economic pragmatism: political-economy essence, antipodes and imitation
Authors:   State Institution “Institute for Economics and Forecasting, NAS of Ukraine”, Mandybura Victor
Published: December 2023

The article reveals the political and economic essence of economic pragmatism as a dialectical-centrist antipode to liberal-monetarism and economic voluntarism. The author gives a theoretical evaluation of the manifestations of new understanding of economic pragmatism in the context of two manifestations of falsification of its political-economic essence. It is proved that the experience of Poland, which is proposed by the "new pragmatism" as a modern model, cannot be implemented in Ukraine in the post-war period to ensure the dynamic development of the real sector on a modern technical and technological basis. From the standpoint of economic pragmatism, it is proved that the "dosed" convergence of "socialist" relations in the economy of a capitalist country cannot be extended to its political, ideological and social spheres. The author reveals the reasons for the fact that the specified unique socio-political and economic symbiosis not only contributed to the dynamic development of China, but provided this country’s evolution to a society of "general welfare" and made it possible to lay the foundations for a long period of development of "market-state socialism".
Oligopoly control and unification of quantitative indexes to control different types of monopoly
Authors:   State Institution “Institute for Economics and Forecasting, NAS of Ukraine”, Bandura Olexandr
Published: December 2023

The paper demonstrates the necessity and possibility to unify the controlling indicators for different types of monopoly (monopolistic competition, oligopoly, natural monopoly) in order to increase efficiency of the monopoly control. Especially this concerns the complex types of monopoly from the point of view of its control, for example, oligopoly. The complexity of this type of monopoly control is associated with the actual inevitability of the appearance of tacit pricing coordination among the oligopoly participants. And the problem is not so much in admitting that the very fact of such a coordination is difficult to prove as in defining the harm it causes to the market and the entire economy. This paper shows the possibility to use the quantitative indexes of monopoly control proposed based on author’s CMI-model of macroeconomic dynamics, to apply these indexes for various types of monopoly. A distinctive feature of this model is the possibility to calculate the vector of “natural” prices for any sector (i.e., the prices that correspond to the state of perfect competition even if it is impossible to reach this state in the existing markets). And the comparison of the actual market price with the “natural” one allows us to control a monopoly using the price indexes alone. In turn, it allows us to perform a monopoly control at various hierarchical levels of the economic system (a firm, an economic sector and economy as a whole). Such a control enables us to calculate the degrees of the monopoly impact both on the entire economy, and on its various sectors. Quantitative values of these degrees can be used as evidence in antitrust litigations and for choice of corresponding instruments to “punish” the monopoly for such abuses. The paper reveals the mechanism of use of the proposed formulas for determination of the monopolistic power and degree of its impact on economy and various economic sectors for the cases of oligopoly and natural monopoly. Also, this paper demonstrates the mechanism of the influence of antimonopoly policy on the configuration of business cycle and on economic growth rate (when other policies are neutral). This opens up the possibility to combine the antitrust policy with the anticyclical and fiscal ones, because, under recession, increased monopolistic power in an individual sector may help the whole economy get out of the crisis.