bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Dynamic Bedroom Lighting On Measures of Sleep and Circadian Rest-Activity Rhythm in Inpatients With Major Depressive Disorder
Authors: Markus Canazei , Johannes Weninger , Wilfried Pohl , Josef Marksteiner , Elisabeth Weiss
Published: October 2021

Bright light therapy is an effective treatment option for seasonal and non-seasonal affective disorders. However up to now, no study has investigated effects of dynamic bedroom lighting in hospitalized patients with major depression. A bedroom lighting system, which automatically delivered artificial dawn and dusk and blue-depleted nighttime lighting (DD-N lighting) was installed in a psychiatric ward. Patients with moderate to severe depression were randomly assigned to stay in bedrooms with the new lighting or standard lighting system. Patients wore wrist actimeters during the first two treatment weeks. Additionally, hospitalization duration and daily psychotropic medication were retrieved from patients’ medical charts. Data from thirty patients were analyzed. Patients under DD-N lighting generally woke up earlier (+20 minutes), slept longer (week 1: +11 min; week 2: +27 min) and showed higher sleep efficiency (+2.4%) and shorter periods of nighttime awakenings (-15 minutes). In the second treatment week, patients started sleep and the most active 10-hour period earlier (-33 min and -64 min, respectively). This pilot study gives first evidence that depressed patients’ sleep and circadian rest/activity system may benefit from adjunctive bedroom lighting when starting inpatient treatment.
Coping strategies adopted by post graduate trainee in dealing with work related stress: (A mixed method study)
Authors: Manzoor Shamaila , Sajjad Madiha , Anwar Idrees , Rafi Aisha
Published: October 2021

Back Ground: During residency period, doctors all around the globe, experiences stressful working environment and prolonged working hours. These factors leads to lack of concentration, distress and higher level of fatigue; however, residents counter the effects of these extensive, high demanding duty hours by various coping strategies. Although the effects of extended duty hours and various coping strategies used by the doctors have been studied at large. Yet, the difference between the effects & coping styles of trainees of various high demanding specialties’ have not been studied. Therefore, this study was carried out to identify and explore the difference in coping strategies for dealing with stress, adopted by post graduate trainees in surgical and non-surgical specialties. Methods: Mixed method approach, with explanatory sequential design was opted for this study. In phase one (quantitative) data was collected by a web based survey; carried out in five teaching hospitals of Rawalpindi & Muzaffarabad in 2020. Data was analysed on SPSS, frequencies and major trends were recorded. An open ended questionnaire was developed on the basis of phase 1 results. In phase two (qualitative), six focus group discussions were carried out with 24 participants to explore the various coping strategies adopted in different situations among the post graduate trainees working in different specialties. Later on, verbatim transcription was done & data analysed manually. Results: Out of 250 (100%) possible participants, 146 (58%) participant responded on-line survey. Where, residents of surgical discipline has a higher response rate (60%, n=87) than non-surgical. Moreover, female participation (54%, n=79) was greater than males (46%, n= 67). Mann-Whitney U test was statistically significant only for seeking medical advice to cope with stress (P= .029). In focus group discussions, female involvement was more (58% n=14) as compare to males (42% n=10). Following themes were developed after data analysis, that is; self-regulation, tailor made strategies, educational focus and support system. Conclusion: Quantitatively, no significant difference was found between the coping strategies of post graduate trainees of surgical & non-surgical trainee, against work related stress. However, minor differences were obtained qualitatively.
The Importance of pH Adjustment for Preventing Fibrin Glue Dissolution in the Stomach: an in Vitro Study
Authors: Takegawa Yoshitaka , Takao Toshitatsu , Sakaguchi Hiroya , Nakai Tatsuya , Takeo Kazuhiro , Morita Yoshinori , Toyonaga Takashi , Kodama Yuzo
Published: October 2021

Background and study aim: Combined use of fibrin glue and polyglycolic acid (PGA) sheets has attracted attention as a preventive measure for complications associated with endoscopic submucosal dissection. However, fibrin glue is a protein that may be dissolved by gastric acid. We evaluated the effect of artificial gastric acid on fibrin clot.Materials and methods: The dissolution time of three layers of fibrin glue with PGA sheets was measured in five groups (pH 1.2, 2.0, 4.0, 5.5, and 6.0 with pepsin). Measurements of three samples per group were made. The mean number of the remaining layers at each measurement point was observed for seven days.Results: The time to complete dissolution of the three layers of fibrin gel in the three samples was 150 minutes at pH 1.2, 5 hours at pH 2.0, 24 hours at pH 4.0, and 2 days and 6 hours at pH 5.5. Conclusion: In order to maintain fibrin glue in the stomach for a long period, there was a need to avoid pepsin activation secondary to acidification of gastric juice. The use of strong antacids is recommended.
Deleterious Oral Habits Related to Vertical, Transverse and Sagittal Dental Malocclusion in Pediatric Patients
Authors: Olivos Lourdes Hilda Gabriela Rodríguez , Chacón-Uscamaita Pamela Roxana , Argote Anthony Quinto , Pumahualcca-Garcia Graciela , Vargas Luis Fernando Pérez
Published: October 2021

Background: Mixed dentition is currently the stage with the highest prevalence of malocclusion, therefore, the objective was to determine the relationship of dental malocclusions in the vertical, transverse, sagittal planes with deleterious habits in pediatric patients. Methods: A cross-sectional analytical study was carried out in 155 children aged 6 to 12 years attended at the clinic of the Dentistry School of The National University of San Marcos in 2017. Results: Of the patients evaluated, 45.3% were identified with vertical malocclusion, 52.0% with sagittal malocclusion and 13.6% with transverse malocclusion. The most frequent type of malocclusion in the vertical plane was anterior deep bite (22.2%), in the transverse plane the Bis a Bis Bite (7.1%) and the Anterior Crossbite (6.5%) were less frequent. Finally, in the sagittal plane, Class II division 1 (20%) and Class III (20.7%) are frequent. Among the most common deleterious habits, anteroposition (58.7%) and mixed breathing (51.0%) were observed in contrast to the habit of retroposition, lip sucking and mouth breathing, which were the least frequent. Considering age and sex, children who have an atypical swallowing habits are more likely to have malocclusion in all three planes of space. Conclusions: It is concluded that there is an association between the deleterious habits with the different types of malocclusion in the different planes of the space, being the atypical swallowing a habit that should be diagnosed early and treated interdisciplinary.
The Impact of Triglyceride-Glucose Index On Incident Cardiovascular Events in Patients With Type 2 Diabetes Mellitus
Authors: Fu Liyao , Tai Shi , Sun Jiaxing , Zhang Ningjie , Zhou Ying , Xing Zhenhua , Wang Yongjun , Zhou Shenghua
Published: October 2021

Background: Previous studies reported the prognostic value of the triglyceride-glucose (TyG) index in the course of cardiovascular (CV) diseases. Still, it remains unclear whether baseline and trajectories of TyG index are prospectively associated with incident CV events among patients with type 2 diabetes mellitus (T2DM).Methods: We performed a secondary analysis in patients with long-lasting T2DM from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study. The primary outcome was the first occurrence of adverse CV events including nonfatal myocardial infarction, nonfatal stroke, or death from cardiovascular causes, and the TyG index was measured at 11 visits. Cox proportional hazards regression analysis was used to observe the association between baseline and trajectories of TyG index and adverse CV outcomes.Results: During a median follow-up period of 8.8 years, 1,815 (17.8%) developed at least one primary endpoint event. After adjusting for traditional cardiovascular risk factors, each 1-SD increase in the TyG index was associated with a 19.00% higher risk of adverse CV events, similar in individuals categorized by TyG index quartiles. Four distinct trajectories of TyG indexes were identified- low (16.17%), moderate (40.01%), high (34.60%), and very high (9.30%). Among these, moderate, high, and very high TyG index trajectories had a greater risk of future incident adverse CV events than low TyG index trajectories after multivariate adjustments for traditional risk factors. Particularly, a similar association was noticed in the TyG index and the occurrence of coronary heart disease.Conclusions: The findings of this study suggest that both baseline and trajectories of TyG index have a significant association with the occurrence of adverse CV events in patients with T2DM. (Trial registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00000620)
Fluorescent Immunological Paper-based Assay for Exosome detection
Authors: Kasetsirikul Surasak , Shiddiky Muhammad J.A. , Nguyen Nam-Trung
Published: October 2021

This paper reports the development of fluorescent-linked immunosorbent paper-based assay for exosome detection. The paper-based device was fabricated with sandwich lamination for easy handling and was coated with exosome-specific antibody as a biosensing platform to detect exosome sample from the cell culture media. This assay employed fluorescent detection which is followed by tagging fluorophore-conjugated detecting antibody on exosome samples. The fluorescent readout was evaluated and quantified from image processing software. This assay can detect high concentration of exosome samples (~ 1010 exosome/mL). However, this assay has encountered various challenges. First, the exosome concentration prepared from cell culture media from cancer-derived ovarian and mesothelial cell lines may be insufficient to reach detectable range. Second, chemical contamination from exosome isolation kits may affect assay sensitivity. Therefore, assay optimization and minimizing chemical contamination are required which could enhance assay specificity and sensitivity.
A sensitive, accurate, and high-throughput gluco-oligosaccharide oxidase based HRP colorimetric method for lytic polysaccharide monooxygenase activity assay
Authors: Liu Gang
Published: October 2021

Background

The AA9 (auxiliary activities) family of lytic polysaccharide monooxygenases (AA9 LPMOs) are ubiquitous and diverse group of enzymes amongst the fungal kingdom. They catalyze the oxidative cleavage of glycosidic bonds in lignocellulose and exhibit great potential for secondary biorefinery applications. Screening of AA9 LPMOs for desirable properties is crucial for biorefinery industrial applications. However, robust, high-throughput and direct method for AA9 LPMO activity assay, which is prerequisite for screening of LPMOs with excellent properties, is still lacking. Here, we have described a gluco-oligosaccharide oxidase (GOOX) based horseradish peroxidase (HRP) colorimetric method for AA9 LPMO activity assay.
Results

We cloned and expressed a GOOX gene from Sarocladium strictum in Trichoderma reesei, purified the recombinant SsGOOX, validated its properties, and set up a SsGOOX based HRP colorimetric method for cellobiose concentration assay. Then we expressed two AA9 LPMOs from Thielavia terrestris, TtAA9F and TtAA9G in T. reesei, purified the recombinant proteins, and analyzed their product profiles and regioselectivity towards phosphoric acid swollen cellulose (PASC). TtAA9F was characterized as a C1 type (class 1) LPMO, while TtAA9G was characterized as a C4 type (class 2) LPMO. Finally, the SsGOOX based HRP colorimetric method was used to quantify the total concentration of reducing lytic products from LPMO reaction, and consequently, the activities of both C1 and C4 types of LPMOs were analyzed. These LPMOs could be effectively analyzed with limits of detection (LoDs) lower than 30 nmol/L, and standard curves between A515 and LPMO concentrations with determination coefficients greater than 0.994 were obtained.
Conclusions

A novel, sensitive and accurate assay method that directly targets the main activity of both C1 and C4 type of AA9 LPMOs was established. This method is easy to use and could be performed on a microtiter plate ready for high-throughput screening of AA9 LPMOs with high properties.
Sustainable business development of private hospitals in Vietnam: Determinants of patient satisfaction, patient loyalty and revisit intention
Authors: Thanh Hai Phan , Thanh Cuong Nguyen , Chien Nguyen Van , Thi Thuong Mai
Published: October 2021

The role of private hospitals is increasingly important in Vietnam. The study aims to determine associations between service quality and hospital brand image with satisfaction and patient loyalty, revisit intention at private hospitals in Vietnam. Quantitative cross-sectional data were collected from 268 patients in DaNang city, Vietnam. Scales to measure hospital service quality, hospital brand image, patient satisfaction, loyalty, and patient revisit intention were developed. The methods used to test the hypotheses of the study include exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and structural equation modeling (SEM). One notable finding in this study provides practical evidence on the relationship of hospital service quality and hospital brand image with patient satisfaction and loyalty. In addition, service quality has a direct influence on patient satisfaction and revisit intention as the indicator of patient loyalty. Meanwhile, hospital brand image has a direct influence on patient loyalty, although it did not influence patient satisfaction. Results of this study help providing the basis for the marketing and customer care programs of private hospitals in DaNang city, Vietnam.
EL DOCENTE Y LOS PROGRAMAS ESCOLARES. LO INSTITUCIONAL Y LO DIDÁCTICO
Authors: Villalobos Torres Elvia Marveya
Published: October 2021

El autor explica el acercamiento al estudio sobre El docente y losprogramas escolares. Asimismo ofrece una visión histórica sobre los programasde estudio en el ámbito de la didáctica: la estructuración del sistemaeducativo, la influencia de la pedagogía alemana, los modeloscentrados en los objetivos y la elaboración de programas.
EL DESARROLLO DE LAS HABILIDADES DE ARGUMENTACIÓN EN DISCUSIONES LITERARIAS EN SALAS DE CLASES: UNA REVISIÓN DE LA LITERATURA
Authors: Orellana García Pelusa
Published: October 2021

El presente artículo señala los avances en la investigación del desarrollo de las habilidades y estrategias de argumentación durante discusiones literarias. La primera parte describe la importancia del desarrollo de estrategias argumentativas y los principales enfoques teóricos utilizados en el estudio de la argumentación. En la segunda parte del artículo, se presenta un análisis crítico de las investigaciones hasta ahora realizadas, en las que se ha explorado el desarrollo y la enseñanza de la argumentación a través de discusiones literarias con alumnos de educación primaria y secundaria. Se describen también los métodos de análisis más utilizados en las investigaciones publicadas y los principales resultados. Finalmente, la tercera parte del artículo expone las líneas de investigación futuras en el campo de la práctica y el ejercicio de la argumentación.
EL EJERCICIO DE LA AUTORIDAD EN LA FAMILIA
Authors: Soberanes Diez María Elinora
Published: October 2021

Actualmente vivimos en una sociedad líquida, como nos indica el sociólogo Zygmunt Barman: nada es sólido ni fuerte. Un rasgo característico de esta sociedad líquida es que vive con las emociones desbordadas.
EL ROL DEL ASESOR EN UN MODELO DE EDUCACIÓN A DISTANCIA
Authors: Martínez Gabriela
Published: October 2021

La educación a distancia cobra auge en la medida en que brinda oportunidades educativas a quienes no pueden o no desean, por diversas razones, recurrir a un sistema escolarizado presencial.

Esta educación no se limita a ir más allá de condiciones espaciotemporales o personales del alumnado. Se trata de una educación con rasgos precisos y fisonomía particular.

El papel del docente aquí es clave para generar eficientes y motivadores ambientes virtuales de aprendizaje.
LA INSTITUCIÓN EDUCATIVA: UN TIPO DE ORGANIZACIÓN
Authors: Parés Gutiérrez Isabel
Published: October 2021

Este artículo parte del análisis conceptual de la organización moderna, en su vertiente específica de organización educativa, cuyos fines están orientados a la mejora integral de la comunidad educativa en la que se encuentra inscrita. Se resalta el papel del director escolar como la figura principal que permite coordinar la actuación armónica de todos los elementos y miembros que componen dicha organización.
EVALUACIÓN DE CAMBIOS EN SENSIBILIDAD INTERCULTURAL EN ESTUDIANTES UNIVERSITARIOS DE CUATRO INSTITUCIONES ESTADOUNIDENSES QUE PARTICIPARON EN EL PROGRAMA DE VERANO DE INMERSIÓN AL ESPAÑOL EN PUEBLA, MÉXICO
Authors: Fabregas Janeiro María G. , Kelsey Kathleen D.
Published: October 2021

El estudio tenía el propósito de evaluar los cambios (si hubiese) en la sensibilidad intercultural de los estudiantes universitarios estadounidenses participantes en un programa de verano, de inmersión al español, en la ciudad de Puebla, México. Fueron evaluados con un instrumento llamado Inventario del desarrollo intercultural (IDI), versión tres (v3). El IDI mide la sensibilidad intercultural y potencialmente puede usarse como un indicador de las competencias interculturales. Participaron catorce estudiantes de cuatro universidades del sur de los Estados Unidos. Su colaboración en este estudio consistió en: 1) proporcionar información demográfica y de algunas experiencias previas a su participación en el curso de español, y 2) responder al instrumento antes y después de su participación en el curso. Los datos proporcionados por el IDI v3 se analizaron empleando Prueba tpara datos apareados. Los resultados mostraron que los estudiantes se encontraban en la etapa de minimización, dentro del Continuum del Desarrollo Intercultural (que incluye las etapas de negación, polarización, minimización, aceptación y adaptación), con una media de 93.08 y 90.91 (en una escala de 145), antes y después de su participación (pre y post) en el curso, respectivamente. Los resultados de las pruebas estadísticas determinaron que no existió cambio estadísticamente significativo en el nivel de sensibilidad intercultural en los estudiantes estadounidenses, como resultado de su participación en el Programa de inmersión al español en Puebla, México.
RÉPLICA A: «EL INDÍGENA COMO SER HUMANO, EN FRAY ALONSO DE LA VERA CRUZ»
Authors: García Casanova María Guadalupe
Published: October 2021

El texto de María Guadalupe García Casanova aborda un personaje y una época poco trabajados en el ámbito de la filosofía de la educación. Como veremos a continuación, el que naciera como Alonso Gutiérrez, en Guadalajara, España, sería un elemento fundamental para entender no solo a pensadores ejemplares de los primeros años de la Colonia y el proceso de evangelización, sino también los procesos educativos, en este caso, tanto en Michoacán como en la capital del país, tomando como ejemplo la primera cátedra de la Real Universidad de la Nueva España, dictada por Alonso de la Vera Cruz.
LA CONSIDERACIÓN HISTÓRICA DE LOS HECHOS EDUCATIVOS
Authors: Meza Mejía Mónica del Carmen
Published: October 2021

Reflexionar sobre el fenómeno que compone el objeto de estudio de la Pedagogía, esto es la educación, remonta a algo tan antiguo como el hombre mismo. La educación por su carácter de hecho humano es también un hecho histórico. El estudio de los hechos humanos es campo de la Historia, la cual indaga y relata las cosas ocurridas, según su etimología griega istoria, que significa relato, narración y exposición de los acontecimientos pasados y dignos de memoria, sean públicos o privados.
DIDÁCTICA Y CURRÍCULO PARA EL DESARROLLO PROFESIONAL DOCENTE
Authors: Galbán Lozano Sara Elvira
Published: October 2021

En el área de educación, la didáctica y el currículo son temas fundamentales y recurrentes cuando de formación profesional se trata. La didáctica como la ciencia que optimiza los procesos de enseñanza aprendizaje; el currículo, como una disciplina de la primera, orientada al desarrollo de planes y programas de estudio.
EL PROCESO DE INVESTIGACIÓN: CONSTRUYENDO EL PROYECTO
Authors: Ortega Barba Claudia Fabiola
Published: October 2021

Cuando se inicia una investigación, no importa bajo qué paradigma1 o enfoque se sustente, es necesario identificarla como un proceso sistemático de indagación o cuestionamiento de algo. Dicho proceso se configura de tres fases: planeación, realización y presentación; dichas fases no son lineales sino recursivas. Este trabajo se enfoca principalmente en la primera fase: el diseño del proyecto de investigación.
LA EDUCACIÓN EN LOS MEDIOS Y LA ACTIVIDAD CIUDADANA
Authors: Naval Concepción , Arbués Elena
Published: October 2021

En la sociedad de la información y de la comunicación, la educación mediática es esencial. Parte del debate que la comunidad educativa mantiene sobre este tema se enmarca en torno a dos cuestiones: ¿por qué educar para el uso de las tecnologías de la información y de la comunicación?; ¿cómo y quién se encarga de este cometido? (Potter, 2010). En este trabajo, trataremos de profundizar en ellas, centrándonos en las políticas educativas adoptadas en diversos países europeos y en las recomendaciones de algunos organismos internacionales (Informe del Parlamento Europeo 2008/2129 (INI). Nuestro interés es contribuir, en alguna medida, a lograr una pedagogía mediática adecuada que favorezca el fomento de la competencia social y cívica y, en última instancia, los conocimientos y las habilidades de participación que conforman el saber ciudadano.
¿CUÁN INVOLUCRADO ESTOY? UN ESTUDIO EXPLORATORIO SOBRE EL COMPROMISO ACADÉMICO Y LA ORIENTACIÓN TEMPORAL EN ESTUDIANTES ARGENTINOS
Authors: Daura Florencia Teresita , Durand Julio César
Published: October 2021

Se presenta una investigación de carácter exploratoria y descriptivaefectuada en una muestra integrada por estudiantes argentinos de nivelmedio, terciario y universitario con dos objetivos precisos: profundizarel estudio sobre el compromiso académico y la orientación temporal; yexaminar la vinculación existente entre ambos constructos.A tal fin, en primer lugar, se describen los fundamentos teóricos de lapropuesta; a continuación, se detallan los instrumentos que se aplicaron,entre los que se destaca una escala diseñada ex profeso dirigida a evaluarel compromiso académico, y el Inventario de Perspectiva Temporal(Zimbardo y Boyd, 1999). Finalmente, se describen los resultadosencontrados, que muestran correlaciones significativas entre las variablesque integran los instrumentos seleccionados para validación, lo quepermitirá utilizarlos en futuras investigaciones sobre el compromisoacadémico.
CIENCIA, TECNOLOGÍA E INNOVACIÓN: CONCEPCIONES DEL PROFESORADO EN EL SALVADOR
Authors: Mendoza Adán
Published: October 2021

Esta investigación tuvo como objetivo identificar las concepciones y creencias de los profesores a partir de la introducción del enfoque Ciencia, Tecnología e Innovación (CTI), en el marco de la implementación del Plan Nacional de Formación Docente (PNFD), por parte del Ministerio de Educación de El Salvador. Se desarrolló un estudio cualitativo por medio de un cuestionario abierto, obteniendo datos de tipo cualitativo y, posteriormente, se realizó un análisis cuantitativo de frecuencias y porcentajes correspondiente a las diversas categorías de ideas recogidas durante la investigación, de tal manera que se trata de un estudio de alcance descriptivo. Los resultados permiten progresar en la comprensión de los avances en las concepciones que tienen los profesores acerca de la enseñanza, el aprendizaje y la evaluación con enfoque de Ciencia, Tecnología e Innovación. Se espera que los hallazgos se conviertan en un insumo para la mejora del profesorado, en cuanto a la fundamentación pedagógica y la inclusión de más recursos e instrumentos propios de las didácticas de las ciencias.
DESARROLLO SOCIO-AFECTIVO EN LA EDUCACIÓN MEDIA SUPERIOR: EL PAPEL DEL CONTEXTO ACADÉMICO
Authors: Ortiz Lack Luis Gerardo , Gaeta González Martha Leticia
Published: October 2021

La transición educativa que actualmente experimenta México pone de relieve a la educación socio-afectiva como parte de una educación de calidad, donde el estudiante aprenda a gestionar sus recursos personales para un adecuado desarrollo en el ambiente donde se desenvuelve. En el nivel medio superior, ello se plantea a lo largo del currículo escolar, por medio de la generación de ambientes de aprendizaje que contribuyan al despliegue de habilidades socioemocionales de los alumnos. El contexto académico constituye, por tanto, un espacio para favorecer el aprendizaje vicario, así como para fortalecer la motivación de los estudiantes hacia el logro de ciertos aprendizajes. Se propone un acercamiento, desde la teoría de la autorregulación emocional de Saarni, para la reflexión sobre el papel preponderante del ambiente académico en el desarrollo de habilidades socio-afectivas de los estudiantes en el nivel medio superior.
DEL παιδαγωγoς AL ACOMPAÑAMIENTO DOMÉSTICO SISTEMÁTICO DE LOS ANTIGUOS NAHUAS
Authors: Rocha Cortés Arturo
Published: October 2021

La noción griega de pedagogo como conductor del pupilo es susceptible de correlación con ciertos elementos descriptivos del tlamatini o sabio de los antiguos nahuas. Empero, en el México antiguo, la índole del acompañamiento del mundo clásico trascendió la noción de traer o llevar a los infantes, con todo y su carácter genuinamente educativo, para privilegiar un acompañamiento sistemático que no trasponía los ámbitos domésticos, sino hasta el momento de transitar el alumno a las casas de enseñanza. Semejante acompañamiento ocurría en el seno de la familia o cenyeliztli, entendida como íntima totalidad doméstica (o, en rigor, económica).
LA INFANCIA EN LA BIBLIA Y SUS CONSECUENCIAS PEDAGÓGICAS
Authors: Angulo Ordorika Ianire
Published: October 2021

Nos guste o no, nuestra cultura occidental nace y crece a la sombra de la religión judeocristiana.La Biblia y el modo de interpretar la realidad, reflejado en ella, han influido demodo inevitable en nuestra sociedad. A pesar de esto, apenas se ha atendido al mundo bíblicoen la historia de la Pedagogía. Conocer cómo la Sagrada Escritura concibe a los niños ycómo se sitúa ante ellos, nos permitirá comprender mejor algunos desarrollos históricos delaprendizaje. Si bien parece que en la mentalidad bíblica la edad adulta giraba en torno a losveinte años, se diferenciaban dos etapas previas a esta: la inmediatamente anterior a la adultezy la infancia. La indefinición de los términos hebreos empleados a la hora de referirse aesta primera etapa vital, podría remitir más a una cuestión sapiencial que a una cronológica.En este artículo pretendemos adquirir una visión panorámica de cómo aborda la Biblia lacuestión de la infancia y las referencias de Jesús respecto a los niños, para extraer de todo elloalgunas consecuencias pedagógicas.
COMPATIBILIDAD DE LAS RUTINAS DE PENSAMIENTO CON EL APRENDIZAJE INTEGRADO DE CONTENIDOS Y LENGUA EXTRANJERA (AICLE): UN ESTUDIO EXPLORATORIO
Authors: López Hernández Alfonso
Published: October 2021

El presente estudio, de carácter exploratorio, aborda las posibilidades de las llamadasrutinas de pensamiento, originadas en el Proyecto Cero de la Universidad de Harvard, encontextos de Aprendizaje Integrado de Contenidos y Lengua Extranjera (AICLE; CLIL, eninglés), con enfoque de enseñanza bilingüe cada vez más común, tanto en Europa comoen Latinoamérica. Se analiza, en primer lugar, la fundamentación teórica del pensamientovisible −marco conceptual del que surgen las rutinas− con especial atención a los puntos encomún relacionados con el papel que la cognición juega en el enfoque AICLE. La segundaparte del estudio expone los resultados de la aplicación sistemática de las siete rutinas básicaso fundamentales con estudiantes de formación de profesorado de un centro universitariode Madrid (España), por un lado, y en tres escuelas de educación primaria, por otro; siempreen ámbitos de aprendizaje de los contenidos curriculares en lengua inglesa. Estas experienciasapuntan al gran valor de las rutinas como estrategia metodológica en el aula AICLE,en especial por su capacidad para fomentar la participación de todo el alumnado −independientementede su competencia lingüística−, sobre todo a través de la formulación depreguntas. Sin embargo, también se señalan algunas limitaciones de esta estrategia, tanto enrelación con su riqueza cognitiva como en su capacidad para generar situaciones de verdaderacomunicación en el aula. Por último, se proponen una serie de preguntas de investigaciónpara investigaciones futuras.
PROPUESTA METODOLÓGICA PARA EVALUAR MODELOS ACADÉMICOS EN INSTITUCIONES EDUCATIVAS
Authors: Quintero Macías Carlos Antonio , Peña Vargas Carmen Silvia
Published: October 2021

El presente artículo tiene como objetivo presentar una propuesta metodológica para evaluar modelos académicos, así como dar a conocer los resultados generales de su implementación en una institución educativa. Para su elaboración se analizaron modelos de evaluación educativos y académicos, así como la revisión de documentos institucionales y datos de entrevistas y focus group, a directivos y docentes. El aporte principal del artículo es la propuesta de evaluación, misma que puede utilizarse para analizar modelos educativos y académicos de otras instituciones educativas, preferentemente de nivel superior. En la parte final se muestran los resultados de la aplicación empírica de la metodología en un centro universitario, a través de la cual se analizó la estructura teórica y conceptual del modelo, su implementación real con distintos actores, así como los resultados a lo largo de los años, vistos a través de los impactos de sus egresados e indicadores institucionales. De tal forma que la propuesta metodológica puede aplicarse para analizar uno o todos los aspectos educativos que se presenten en las instituciones.
LA INTERCULTURALIDAD HOY, COMO TENDENCIA EDUCATIVA
Authors: Chavarría Olarte Marcela
Published: October 2021

Hoy, la educación está matizada por múltiples tendencias, producto del sorprendente avance de la ciencia y la tecnología, la reducción de tiempos y distancias en los procesos de comunicación y la globalización cultural. El reto pedagógico es, pues, educar «para la vida» en un mundo globalizado, formar en la interculturalidad que acerque a los pueblos y a las personas en el encuentro con distintas formas de expresión de unos mismos valores. El presente escrito guía la reflexión pedagógica en torno a los signos que caracterizan los primeros años del nuevo siglo y milenio; se pregunta sobre el papel de los educadores en esta etapa de la Historia; plantea la necesidad de formar en habilidades del pensamiento y la acción para forjar y afrontar escenarios futuros; describe seis tendencias educativas presentes a nivel internacional; y esboza algunos rasgos que han de caracterizar a un modelo educativo de calidad.
LA VERDAD Y LA EVALUACIÓN EDUCATIVA
Authors: Pliego Ballesteros María
Published: October 2021

Sólo si vinculamos verdad y evaluación, podremos aspirara que ésta sea educativa. Si respetamos los niveles y camposdel saber, nos elevamos desde el conocimiento vulgar –queparte de la cogitativa para evaluar– al conocimiento científico–que averigua las causas próximas de la evaluación, utilizandoinstrumentos para contar, medir o valorar el proceso deenseñanza aprendizaje–. Después, el conocimiento filosóficoprofundiza más en las causas primeras de la evaluación; y elconocimiento teológico nos indica cómo sólo Dios puedeevaluarnos, con su infinita Justicia y Misericordia, en nuestratotalidad.
PROPUESTAS Y ALTERNATIVAS PARA LA EDUCACIÓN EMOCIONAL
Authors: Roger Acuña Santiago , López Aymes Gabriela
Published: October 2021

Este escrito plantea la necesidad de trabajar, en la escuela, contenidos de tipo emocional y afectivo que contribuyan al desarrollo integral de los estudiantes. En tal sentido, luego de precisar algunas concepciones acerca de las emociones, se revisa el constructo de la inteligencia emocional y su relación con otros enfoques actuales sobre la inteligencia. También se abordan algunos estudios evolutivos recientes sobre la comprensión y el manejo de las emociones en conflicto. Finalmente, se proponen estrategias y actividades para desarrollar programas educativos en el campo afectivo-emocional.
INTELIGENCIA EMOCIONAL Y DESEMPEÑO ESCOLAR
Authors: Álvarez Manilla José Manuel , Valdés Krieg Ernesto , Curiel de Valdés Ana Bertha
Published: October 2021

El concepto de «Inteligencia Emocional» ha adquiridomucha popularidad en años recientes. Diversos autores hanafirmado que la Inteligencia Emocional y su perfeccionamiento,tienen tanta importancia como la inteligencia cognitivapara el desarrollo pleno de las personas en los ámbitospersonal, familiar, escolar y laboral.Este trabajo analiza los factores básicos que conforman elconcepto de Inteligencia Emocional y su medición, así comola construcción de una encuesta para medir esos factores.Se puede concluir que los principales factores que se hapostulado que conforman la Inteligencia Emocional poseensólo una influencia indirecta en el desempeño escolar; entanto que los elementos relacionados con el carácter de losindividuos, sí influyen directamente en este desempeño.
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19
Authors: Ferreira Kleber , Rigoli Isabel , Silva Marcus , Espeleta Alexandre , Rocha Zênis
Published: October 2021

ALCOHOL GEL FOR ASEPSY OF THE HANDS – PROPER FORMULATION AND GUARANTEED EFFICIENCY AMID THE PANDEMIC OF COVID-19. The use of hand antiseptics became widespread as a routine in the fight against COVID-19. In the market, the availability and purchase of substandard antiseptics create a permanent concern with safety, even after a pandemic. Therefore, the development of easy-to-deploy analytical methods for the quality control of alcohol-based hand antiseptics is needed. In this work, to determine the ethanol content in alcohol gel the use of refractometry and alcohol oxidation method by dichromate accompanied by UV-Vis spectroscopy were applied. The results indicated that 19 brands (out of the 70 evaluated) (27.1%) had levels of ethyl alcohol below the recommended level (68.25%), therefore, they are ineffective for hand asepsis. For the quality control of hand antiseptics, refractometry and the oxidation-reduction reaction are complementary analytical methodologies. As a quick, inexpensive screening method, refractometry provides a more suitable technique. However, the interference of emollients may affect the accuracy of the ethanol content determination. Therefore, applying the ethanol oxidation method coupled with electronic spectroscopy offers a simple and broadly accessible method to confirm the ethanol content in alcohol-based hand antiseptics. In addition to developing quality control protocols, is also described the 3.5-ton production of alcohol gel at the Federal University of Bahia.
COMPARANDO O DESEMPENHO DE DOIS ANALISADORES DE MASSAS (FT-ICR MS & LTQ MS): UMA AULA EXPERIMENTAL SOBRE ANÁLISE DE COMPOSTOS ORGÂNICOS
Authors: Lyrio Marcos , Feu Amanda , Motta Larissa , Figueroa Laura , Boasquevisque Leonardo , Pinto Roberta , Rosa Ana , Arantes Heryson , Bottocim Ramon , Fonseca Victor , Santos Nayara , Lacerda Valdemar , Castro Eustaquio , Romão Wanderson
Published: October 2021

COMPARING THE PERFORMANCE OF TWO MASS ANALYZERS (FT-ICR MS & LTQ MS): AN EXPERIMENTAL CLASS ON ANALYSIS OF ORGANIC COMPOUNDS. Mass spectrometry (MS) is a high-performance analytical technique that allows a measurement of the mass/charge (m/z) ratio of compounds present in a sample. MS is able to separate two m/z ions with determined values (mass resolution), being an important characteristic, especially in the analysis of biochemical components and complex mixtures. Mass analyzers define the resolving power and accuracy of different types of mass spectrometers. Herein, the performance of two mass analyzers (Fourier Transform Ion Cyclotronic Resonance (FT-ICR) and quadrupole ion trap (LTQ)) was tested on low (Mw = 165-679 Da) and high (Mw = 783-8.58 kDa) molecular weight molecules (Phenacetin, Procaine, Benzocaine, Caffeine anhydrous, Lidocaine, two metal porphyrin standards, the first cobalt and the second vanadium, and two protein standards, Ubiquitin and Beauvericin), and finally, for an oil sample. LTQ-MS and FT-ICR-MS had similar performance and high reproducibility. However, the mass accuracy and resolution power of the FT-ICR (error lower than 5 ppm and RP higher than 400,000) was higher, being therefore, it was more suitable for the analysis of proteins and oil, for instance. On the other hand, the CID analysis via LTQ demonstrated its applicability in fragmentation experiments, being able to determinate the chemical connectivity of organic compounds in non-complex mixtures.
The Impact of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Epithelial Ovarian Cancer
Authors: Kirat Samet , Akgor Utku
Published: October 2021

OBJECTIVE: This study aims to investigate the prognostic value of the preoperative neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with epithelial ovarian cancer.
STUDY DESIGN: Between January 2012 and December 2018, the data and preoperative levels of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio of 116 epithelial ovarian cancer patients were retrospectively collected. The association of these relevant markers with outcomes was analyzed.
RESULTS: The difference was observed concerning optimal and suboptimal debulking in platelet-to-lymphocyte ratio ratios (p=0.04). Lymphovascular space involvement was significantly associated with higher platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio ratios (p<0.0001). Patients with ascites and lymph node involvement had a higher platelet-to-lymphocyte ratio ratio (p=0.007 and p=0.004). In recurrences, higher ratios of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio were observed (p=0.03 and p=0.02). The analysis revealed that platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio were not independent prognostic factors for recurrence (p=0.783 and p=0.391). Regarding mortality, platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio were not independently prognostic (p=0.621 and p=0.830). It was determined that neutrophil-to-lymphocyte ratio >2.45 (HR 0.714, CI 0.622-0.794, p<0.0001) and platelet-to-lymphocyte ratio >179.4 (HR 0.736, CI 0.646-0.814, p<0.0001) could predict the presence of recurrence with a certain sensitivity and specificity, and for predicting the death, a neutrophil-to-lymphocyte ratio of >2.45 had a sensitivity of 78.26% (95% CI: 56.3 to 92.5%) and a specificity of 54.84% (95%CI: 44.2 - 65.2) (p=0.03).
CONCLUSION: The evaluation of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio is important in obtaining prognostic information before surgery. However, no significant association between the neutrophil-to-lymphocyte ratio or platelet-to-lymphocyte ratio with survival was identified.
Self–Training With Quantile Errors for Multivariate Missing Data Imputation for Regression Problems in Electronic Medical Records: Algorithm Development Study (Preprint)
Authors: Gwon Hansle , Ahn Imjin , Kim Yunha , Kang Hee Jun , Seo Hyeram , Cho Ha Na , Choi Heejung , Jun Tae Joon , Kim Young-Hak
Published: October 2021

BACKGROUND

When using machine learning in the real world, the missing value problem is the first problem encountered. Methods to impute this missing value include statistical methods such as mean, expectation-maximization, and multiple imputations by chained equations (MICE) as well as machine learning methods such as multilayer perceptron, k-nearest neighbor, and decision tree.

OBJECTIVE

The objective of this study was to impute numeric medical data such as physical data and laboratory data. We aimed to effectively impute data using a progressive method called self-training in the medical field where training data are scarce.

METHODS

In this paper, we propose a self-training method that gradually increases the available data. Models trained with complete data predict the missing values in incomplete data. Among the incomplete data, the data in which the missing value is validly predicted are incorporated into the complete data. Using the predicted value as the actual value is called pseudolabeling. This process is repeated until the condition is satisfied. The most important part of this process is how to evaluate the accuracy of pseudolabels. They can be evaluated by observing the effect of the pseudolabeled data on the performance of the model.

RESULTS

In self-training using random forest (RF), mean squared error was up to 12% lower than pure RF, and the Pearson correlation coefficient was 0.1% higher. This difference was confirmed statistically. In the Friedman test performed on MICE and RF, self-training showed a P value between .003 and .02. A Wilcoxon signed-rank test performed on the mean imputation showed the lowest possible P value, 3.05e-5, in all situations.

CONCLUSIONS

Self-training showed significant results in comparing the predicted values and actual values, but it needs to be verified in an actual machine learning system. And self-training has the potential to improve performance according to the pseudolabel evaluation method, which will be the main subject of our future research.
Organizations’ Strategies to Improve Implementation of Universal Accessibility Principles: Protocol for a Scoping Review (Preprint)
Authors: Corcuff Maëlle , Routhier François , Paquette-Raynard Emmanuelle , Gagnon Martine , Battalova Alfiya , Mwaka Claudel , Lamontagne Marie-Eve
Published: October 2021

BACKGROUND

Since the publication of the Convention on the Rights of Persons with Disabilities, several countries have adopted laws, policies, and action plans to improve the universal accessibility of environments to improve inclusion and social participation of all citizens. Different organizations are involved in the application of these measures.

OBJECTIVE

The aim of this study is to identify strategies that are contextually appropriate and provide guidelines for organizations to promote successful implementation of universal accessibility.

METHODS

We will conduct a scoping review identifying implementation strategies of universal accessibility measures in local organizations using the Arksey and O’Malley framework. We will search in Medline, CINHAL, Urban Studies Abstracts, ABI Inform, and Social Sciences Full Text from 2006 until today, following the adoption of the Convention on the Rights of Persons with Disabilities. Two reviewers will independently select studies for inclusion and will extract the data. A descriptive and thematic analysis of the characteristics of the identified implementation strategies will be performed.

RESULTS

Implementation strategies will be summarized in tables. They will then be linked to various constructs and domains listed in the Theoretical Domain Framework to identify barriers and facilitators of organizations’ uptake of evidence-based strategies of implementation.

CONCLUSIONS

We will tabulate the characteristics of the included studies and the outcomes of implementation strategies in them. The results of this scoping review are expected to help the research community in various fields, local organizations, and stakeholders to identify better ways to improve implementation strategies of universal accessibility practices.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/33641
The Importance of Exploring the Role of Anger in People With Psoriasis (Preprint)
Authors: Hughes Olivia , Hunter Rachael
Published: October 2021

UNSTRUCTURED

N/A.
Nudges as Behavior Change Interventions to Improve Health and Well-Being. Protocol for a scoping review (Preprint)
Authors: Duarte Anselmi Giuliano , Ortiz Luis , Figueroa Oriana , Laroze Denise
Published: October 2021

UNSTRUCTURED

Objective
Our objective is to map and summarize the evidence on nudges that assess behavior change interventions to improve health and well-being.
Design
This is the protocol for a scoping review
Data source
A comprehensive search will be conducted on Cochrane database of systematic reviews (CDSR); Database of Abstracts of Reviews of Effectiveness (DARE); HTA Database; PubMed; LILACS; CINAHL; PsyclNFO; EMBASE; EPPI-Centre Evidence Library; WHO institutional Repository for information Sharing; NICE public health guidelines and systematic reviews; through an advanced search in the Epistemonikos platform. The search will cover the period until the day before this protocol is submitted to a journal.
Eligibility criteria for study selection and methods
Only systematic reviews (SR) will be included, which are operationally defined as any secondary research that includes only primary clinical studies, with the above search strategy applied in at least two databases that have assessed the use of nudges related to health, including SR of broader scope. Primary studies, clinical practice guides, abstracts and other evidence summary designs will be excluded.
The electronic search results will be added according to the inclusion criteria. This manuscript will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) [10]
Ethics and Dissemination
Ethical approval is deemed unnecessary. The results of this review will be widely disseminated through peer reviewed publications, social networks and traditional media.
Dichloroethane poisoning
Authors: Arustamian O.M. , Tkachyshyn V.S. , Kondratiuk V.E. , Aleksiichuk A.Y. , Dumka I.V.
Published: October 2021

Diagnosis and treatment of acute poisoning from dichloroethane remain a very urgent task for clinical toxicology and clinical laboratory diagnostics since it belongs to the group of potent poisonous substances, the poisoning from which is the most severe. Dichloroethane belongs to organochlorine compounds and is a volatile liquid with a specific aromatic odor, very soluble in alcohol and fats. This substance is used not only for industrial purposes but also for household purposes. It is used as a raw material for the production of plastics. It has a fragrant odor, promotes ingestion for intoxication. Dichloroethane is produced in huge quantities and is used in the production of polyvinylchloride and other polymeric materials, fumigants, and adhesives. Death can occur even after taking 10–20 ml of dichloroethane. When ingested, the maximum concentration of substances in the blood is reached after 3–4 hours from the moment of taking, and the rate of absorption increases when taken together with alcohol and fats. Absorbed into the blood, toxic substances accumulate in lipid-rich tissues (brain, liver, omentum, adrenal glands). The toxicity of dichloroethane is due to its metabolism into chloroethanol and monochloroacetic acid, which on the first day determine the clinical picture of a narcotic and depressive effect on the central nervous system and exotoxic shock (at doses exceeding lethal doses), toxic liver dystrophy (on days 2–5), toxic nephropathy, gastrointestinal syndrome. Preventive measures for dichloroethane poisoning include compliance with all safety rules at work and home. Employees of enterprises dealing with this toxic substance must work in rooms with constantly forced ventilation, in industrial filter respirators (gas masks), and protective clothing.