bluuebunny/crossref_metadata_2025 huggingface dataset:
Photodynamic therapy of malignant brain gliomas
Authors: Rozumenko Volodymyr D. , Liubich Larysa D. , Staino Larysa P. , Egorova Diana M. , Malysheva Tetyana А. , Dashchakovskyi Andrii V.
Published: January 2023

Treatment of malignant gliomas of the brain remains a serious problem on a global scale, despite intensive research into the causes and mechanisms of their progression. When using traditional surgical approaches and imaging methods tumor cell infiltrates may be overlooked, as a result of which, malignant gliomas relapse often occurs near the marginal region of the surgical cavity. A method that allows visual identification of tumor tissue and at the same time provides an opportunity to selectively destroy it is photodynamic therapy (PDT) ‒ a two-stage treatment that includes the introduction (intravenous, intraperitoneal, local or oral) of a light-sensitive chemical agent (photosensitizer (PS)) followed by its activation at a certain wavelength of light.The principle of PDT is based on the cytotoxic effects caused by PS, which selectively accumulates in malignant tumor cells and is activated by light rays of the appropriate wavelength, generating singlet oxygen and free radicals, which trigger photochemical reactions in tumor cells with subsequent destruction of protein structures. Tumor tissue has a higher affinity for PSs. PSs are divided into 1st, 2nd and 3rd generation molecules. So far, 3rd generation PSs have not yet been approved for clinical use. In vitro and in vivo experimental studies confirmed the effectiveness of PDT of brain tumors using 2nd generation PSs.The simultaneous use of surgery under the control of fluorescence and PDT enables both the visualization of tumor cells and their selective destruction. Regardless of PDT, PSs are used for the purpose of auxiliary delineation of tumor borders for maximum tumor removal during fluorescence-guided surgery.The review examines the development of PDT in a historical aspect, the contribution of domestic scientists, in particular, scientists of the Institute of Neurosurgery named after acad. A. P. Romodanov, National Academy of Medical Sciences of Ukraine to the development of the problem of PDT in neuro-oncology; preclinical studies of PDT and experimental approaches to increase the efficiency of PDT are characterized. Analysis of data from clinical trials confirms that using PDT as an adjunctive treatment of malignant gliomas administered immediately after maximal resection is safe, reduces the risk of recurrence by targeting residual tumor cells in the resection cavity, improves survival and quality of life of patients. The absence of information on the development of resistance to multiple PDT sessions suggests the possibility of repeated treatments of tumor cells not removed during surgery.
Single nucleotide polymorphisms of intervertebral disc collagens and prospects for their correction
Authors: Pedachenko Eugene G. , Vasilyeva Iryna.G.
Published: January 2023

The main functions of the intervertebral disc (IVD) are ensured by the reliable integration of three structures of the IVD: the annulus fibrosus (AF), the hydrated nucleus pulposus (NP) and the two cartilaginous end plates (CEP). All molecular components are involved in the integration of the three anatomical structures of the IVD, however, the most important biomechanical properties - resistance to rupture / stretching / shift, resistance to static axial loads are mostly determined by collagens.The unique properties of collagens depend on the amino acid sequence of the three alpha (α) chains, which, after spiralization and condensation, form the collagen molecule - tropocollagen. The amino acid sequence contains all the necessary information for spiralization, modification, secretion of tropocollagen, its processing, condensation into fibrils and fibers according to the self-assembly principle. Changes in the primary amino acid sequence, depending on the substitution itself and its localization, lead to disruption of the stages of tropocollagen formation, its extracellular processing, and condensation.Currently, most of the research is devoted to the study of polymorphisms in the genes of IVD collagen types I, II, IX and XI. Algorithms for using information about genetic polymorphisms of collagen genes are only being formed. Data on genetic variation are often conflicting. An important aspect is the homogeneity of the study group by age, ethnicity, gender, as well as by the type of degenerative changes. There is also insufficient data on the effect of polymorphism on the properties of the collagen molecule, which greatly complicates the creation of standards for therapeutic correction.This literature review is devoted to the consideration of new data on collagen genes polymorphisms, the impact of these polymorphisms on integrative relationships in IVD structures, as well as the prospects for the correction of genetic abnormalities.
ANALISIS PELUANG BISNIS DI MASA PANDEMI (Studi Kasus pada PT Unilever Indonesia Tbk)
Authors: H Annisah Fildzania , Sahputri Andriani , Nurbaiti Nurbaiti
Published: January 2023

Adanya pandemi COVID-19 mengakibatkan berubahnya perilaku masyarakat, serta semakin banyaknya teknologi-teknologi baru yang muncul untuk dapat dimanfaatkan masyarakat di dalam kehidupan sehari-hari dan juga dapat dimanfaatkan oleh suatu organisasi atau perusahaan dalam mempertahankan dan mengembangkan keunggulannya. Penelitiaan ini bertujuan untuk mengetahui strategi PT. Unilever dalam memanfaatkan peluang pada saat pandemic dengan menggunakan analisis SWOT. Jenis penelitian yang digunakan adalah ekspanatori research, dan dengan menggunakan pendekatan kualitatif. Metode penelitian yang dilakukan adalah metode mengumpulkan data dari berbagai sumber yang ada di internet, kemudian menghubungkan sumber-sumber tersebut menjadi satu. Teknik pengumpulan data yang digunakan adalah mencari informasi dari berbagai literatur. Berdasarkan hasil yang didapatkan dari berbagai sumber, dapat dikatakan bahwa PT. Unilever tetap dapat memenuhi kebutuhan konsumennya dan terus berorientasi jangka panjang, seperti dengan menghadirkan produk-produk dalam ukuran kemasan ekonomis, dan harga yang terjangkau serta banyak menciptakan inovasi di bidang digital.
PENGARUH KOMPETENSI SUMBERDAYA MANUSIA DAN TEKNOLOGI INFORMASI TERHADAP KUALITAS LAPORAN KEUANGAN PUSKESMAS BLUD DINAS KESEHATAN KABUPATEN DELI SERDANG
Authors: Wismoyo Uan , Nasution Juliana
Published: January 2023

Penelitian ini bertujuan untuk mengetahui pengaruh kompetensi sumber daya manusia dan pemanfaatan teknologi informasi terhadap kualitas laporan keuangan pada Puskesmas Blud Dinas Kesehatan Kabupaten Deli Serdang. Responden dalam penelitian ini adalah kepala dan staf sub bagian akuntansi dan keuangan pada penyusunan laporan keuangan Puskesmas Blud. Jumlah responden dalam penelitian ini adalah 33 orang. Pengumpulan data dilakukan dengan menyebarkan kuesioner secara langsung ke masing-masing puskesmas. Teknik analisis data menggunakan analisis regresi linear berganda. Hasil pengujian pada masing-masing variabel bebas menunjukkan bahwa kompetensi sumber daya manusia berpengaruh terhadap kualitas laporan keuangan. Sedangkan penggunaan teknologi informasi tidak mempengaruhi kualitas laporan keuangan Puskesmas.
Strategi UMKM Dalam Menghadapi Pasca Pandemi COVID-19
Authors: Laksamana Rio , Indra Sukma , Rusmita Sari
Published: January 2023

Penelitian ini juga bertujuan untuk mengetahui strategi yang telah UMKM terapkan (baik dari hasil penelitian sebelumnya maupun strategi yang diberikan pemerintah) dan kendala yang dihadapi UMKM dalam menerapkan strategi. Penelitian ini menggunakan data primer dari koesioner yang tersebar kepada 500 responden yang merupakan pelakuk UMKM. Hasil penelitian ini menemukan bahwa sebagian besar responden pengusaha UMKM telah menerapkan startegi penelitian sebelumnya dan strategi yang di berikan oleh pemerintah berkaitan dalam berkelangsungan usaha (melaksanakan protokol kesehatan, bantuan pemerintah, menjaga produk berkualitas dan pemanfaatan teknologi), agar dapat bertahan dan beradaptasi di masa pandemi Covid-19.
Implementasi Multibeam Echosounder untuk Pengukuran dan Analisis Data Kedalaman Perairan Teluk Jakarta Berdasarkan Standar International Hydrographic Organization
Authors: Nugroho Christian , Manik Henry , Gultom Dwiadji , Firdaus Muhammad
Published: January 2023

Sebagian besar wilayah Indonesia adalah perairan laut dengan luas meliputi dua pertiga luas wilayah negara. Survei hidrografi menggunakan multibeam dinilai lebih efektif dan efisien dalam mengeksplorasi laut terutama kondisi dasar laut apabila dibandingkan dengan single beam echosounder.  Perairan Teluk Jakarta yang dangkal dengan kegiatan maritim yang padat terutama arus lalu-lintas pelayaran memerlukan pemahaman yang kritis dan spesifik untuk menjaga keselamatan navigasi di laut. Untuk itu diperlukan standar survei dalam pengambilan dan pengolahan data multibeam yaitu aturan standar berdasarkanInternational Hydrographic Organization (IHO) yang memuat kalibrasi patch test, kalibrasi offset statik, koreksi pasang surut, dan koreksi kecepatan rambat suara dalam air dan uji kualitas data. Data multibeam yang diperoleh telah dikalibrasi dan dikoreksi dengan hasil uji kualitas  pada orde spesial sebesar 97.47%.  Pengukuran multibeam menghasilkan data kedalaman maksimum perairan  Teluk Jakarta sebesar 10.92 m, kedalaman minimum sebesar 5.84 m, dan rata-rata kedalaman 8.26 m. Interpretasi morfologi dan topografi dasar laut membentuk alur cekungan seperti parit dengan asumsi hasil pengerukan atau erosi.  Analisis data kedalaman menunjukkan terdapat area pendangkalan di sisi barat daya cekungan dengan diperoleh adanya dua titik kedangkalan.
Anaerobic Hydroxylation of C(sp3)–H Bonds Enabled by the Synergistic Nature of Photoexcited Nitroarenes
Authors: Paolillo Joshua , Duke Alana , Gogarnoiu Emma , Wise Dan , Parasram Marvin
Published: January 2023

A photoexcited nitroarene-mediated, anaerobic C–H hydroxylation of aliphatic systems is reported. The success of this reaction is due to the bifunctional nature of the photoexcited nitroarenes, which serve as the C–H bond activator and the oxygen atom source. Compared to previous methods, this approach is cost and atom economical due to the commercial availability of the nitroarene, the sole mediator of the reaction. Owing to the anaerobic conditions of the transformation, a noteworthy expansion in substrate scope can be obtained compared to prior reports. Mechanistic studies support that the photoexcited nitroarenes engage in successive hydrogen atom transfer and radical recombination events with hydrocarbons, leading to N-arylhydroxylamine ether intermediates. Spontaneous fragmentation of these intermediates leads to the key oxygen atom transfer products.
On the molecular dynamic of quercetin and chitosan behavior in water and 1-octhanol at different temperatures
Authors: Stefani Ricardo , Silva Aguiar Isabelle
Published: January 2023

rug delivery control systems allow the controlled transportation of therapeutic agents. In order to understand the behavour of chitosan as a drug delivery system, the behaviour of chitosan and quercetin in water and 1-octanol at 300 K and 310 K as a complex was calculated with molecular dynamics (MD) calculations. Meanwhile, Molecular docking (MDK) were used to make the complex of these molecules. Of nine quercetin’s conformations around chitosan, two were chosen to make a complex due to better energy affinity. The molecules interact between each other with hydrogen bonds. The molecules do not interact with 1-octanol, independent of temperature. In water, chitosan maintained insoluble with the increase of temperature. On the other hand, quercetin demonstrated a better solubilization with temperature increasement. The complex demonstrate a behaviour favorable to a drug delivery control system.
Synthesis of 1,6/7-(NO2)2Perylenediimide and 1,6/7-(NH2)2Perylenediimide: Regioisomerically Pure Materials for Organic Electronics
Authors: Gapin Adèle , David Arthur , Allain Magali , Masson Dorian , Alévêque Olivier , Ave Thomas , Le Bras Laura , Hudhomme Pietrick , Goujon Antoine
Published: January 2023

The use of perylenediimide (PDI) building blocks in materials for organic electronic is of considerable interest. The introduction of peripheral groups in their ortho and bay positions radically modify their optoelectronic properties. In this article, we describe an efficient method to afford regioisomerically pure 1,6/7-(NO2)2- and (NH2)2-PDIs employing two key steps: the selective crystallization of 1,6-(NO2)2-perylene-3,4,9,10-tetracarboxy tetrabutylester and the nitration of regiopure 1,7-Br2-PDI with silver nitrite. The optoelectronic properties of the resulting regioisomerically pure dinitro, diamino-PDIs and bisazacoronenediimides (BACDs) are reported and demonstrate the need to separate both regioisomers of such n-type organic semiconductors for their inclusion in advanced optoelectronic devices.
The Fear of Crime factors and Application of CPTED in Public Toilets
Authors:   KOREA CPTED ASSOCIATION, Cha YooJung , Song Jeong-hwa
Published: January 2023

This study focuses on identifying the factors affecting fear of crime in public toilets that people may experience through actual crime cases in public toilets and suggesting applicable implications of CPTED.
In this study, we examined the number of crimes related to public toilets over the past five years through official crime statistics. In addition, we reviewed specific cases of public toilet crimes through Internet articles and legal precedents. Particularly, through the cases, we examined which specific characteristics of toilets such as the location of men’s and women’s entrances and the absence of emergency bells might have led to crimes.
Lastly, we suggested various elements of the fear of crime in public toilets and CPTED application ways.
A Study on the Dissemination and Development Process of Crime Prevention Environment Design in Japan
Authors:   KOREA CPTED ASSOCIATION, Jang Rebecca , Yoon Cheol-Jae
Published: January 2023

This study attempted to examine the development process of introducing and disseminating crime prevention environment design in Japan, which has a similar social and cultural environment to Korea. Japan's CPTED, which began to be distributed mainly by the Japan Housing Corporation(currently the UR Urban Regeneration Organization) and the National Police Agency, was presented as a methodology that emphasized the improvement of the physical environment based on the location. However, since then, the subjects of activities have been diversified from public to private institutions, such as central government ministries, local governments, private business operators, and residents. In addition, the area of spatial application to educational institutions, roads, parking lots, and parks, including public housing, has been expanded, and community-participating software activities such as the establishment of living safety ordinances for each local government, the introduction of private security towns, and community-related volunteer activities are also emphasized as countermeasures. Through this case study of CPTED in Japan, it can be seen that in order to maintain a sustainable crime prevention environment, territorial integrity must be established through the creation of a physical and legal environment and the daily community activation of local members.
Analysis on the Trends of CPTED Research Using Text-Mining Techniques
Authors:   KOREA CPTED ASSOCIATION, An Eun-Hee
Published: January 2023

The purpose of this study is to examine the trends of CPTED research using Text-Mining. For this purpose, 1559 keywords were collected from 718 papers that registered ‘CPTED’ as the keyword or abstract through the Korean Journal Citation Information. Collected keywords were used for TF-IDF, Network analysis and Topic modeling through Textom program. The results of the analysis are as follows: First, Centrality analysis showed that CPTED researchs had been conducted focusing on keywords like ‘CPTED’, ‘crime prevention’, ‘fear of crime’, ‘crime’, CCTV’ and so on. Second, five topics were extracted: ‘CPTED women’s safety’, ‘CPTED apartment complex’, ‘CPTED urban regeneration’, ‘CPTED by facility’, and ‘CPTED design guidelines’. Since the foundation of Korea CPTED Association in 2010 and the enactment of CPTED in 2014, the diversification of CPTED research subjects has been made. Quantitative analysis using Text-Mining provides useful results for development of CPTED research.
The Effect of School CCTVs on Prevention of the School Bullying in the Daejeon Metropolitan City
Authors:   KOREA CPTED ASSOCIATION, Song Se-yoon , Kim Kirl
Published: January 2023

The debates on the effect of school CCTVs on prevention of the school bullying are controversial. The purpose of this study is to look into the effects of school CCTV on prevention of the school bullying in the Daejeon Metropolitan City using multiple regression analysis and suggest the policy implications for the improvement of the school CCTV. First of all, this study focused on the preceding literature reviews dealing with the Crime Prevention Through Environmental Design(CPTED). Second, it searched for the school CCTV installation status by autonomous districts and school levels in the Daejeon Metropolitan City. Third, it also performed the multiple regression analysis to investigate the effects of school CCTV on prevention of the school bullying. The result meant that the enlargement of school CCTVs in the Daejeon Metropolitan City were ineffective with the decrease in the school bullying. It suggests that both the quantitative increase in the school CCTV and the interactions between teachers and students should be combined on the base of defensible mechanisms such as the machine surveillance through the CCTV.
The Origin of Pottery as a Result of Human Adaptive and Imitative Activity
Authors:   Institute of Archaeology RAS, Tsetlin Yu. B.
Published: January 2023

The study of the origin of pottery production includes a consideration of two important questions: 1) Why pottery production appeared? and 2) How it was? In European and American archaeological literature, we can find various approaches to these issues. This article proves the fact that pottery production appeared in the result of gradual accumulation of concrete human knowledge about the useful features of different natural materials distributed in the environment. The all useful knowledge in pottery making was found only by cut-and-try method. It was a long-time and step by step process, when positive acquirements became a part of local cultural traditions which passed down from generation to generation. Resemblance between stone, wicker, and clay vessels in general proportionality and volume shows that the emergence of pottery was an obligate course of development, when different natural materials were tested. The process had been finished by widespread distribution of clay vessels as universal things by their function. Since the emergence of pottery production was a polycentric process, a concrete ways of pottery technology development were different in various natural and climatic conditions. But in any cases, this process obeyed general laws, which are consisted in gradual knowing about important qualities of silt and then of clay plastic raw materials. The change from silt to clay was manifested itself in special imitation of complex constituent of silt by adding of different organic or mineral tempers in natural clay. The author shows that the development of vessels’ shapes passed from the use of natural containers then to artificial containers made of natural materials, and finally to artificial ones made of new special constructional materials (i.e., pottery pastes). Such clay containers could be fired with various regimes. So, we can do a conclusion, that the origin of pottery production was an obligate historical process of human adaptation to the natural environment, its imitation, and finally to the making a new artificial material which are absent in the world.
Experience of Reconstructing the Appearance of an Early Neolithic Human from a Burial at the Shumilikha Cemetery (Southern Angara Region)
Authors: Galeev R. M. ,   N.N. Miklukho-Maklai Institute of Ethnology and Anthropology, RAS, Berdnikova N. E. , Berdnikov I. M. , Spasibko A. B. ,   Irkutsk State University,   Irkutsk State University,   Irkutsk State University
Published: January 2023

This paper presents the results of a reconstruction of the appearance of a hunter-gatherer of the Kitoi culture from a burial at the Shumilikha cemetery in the Southern Angara region. The excavations were carried out in 1999. In the grave, the walls of which were coated with clay, the remains of a human 25–35 years old were found. Under the skeleton, which was sprinkled with “ocher” (grated hematite rock), traces of a wooden construction were recorded. The grave goods (more than a hundred items) included such interesting finds as the kernels of fishhooks, a bone spoon, beads made of bone paste, as well as two items made of white jade: a ring and a cylindrical bead. There is a reliable radiocarbon date for the human bone, which, taking into account the correction for the reservoir effect, shows an age of 7,003±106 cal BP and allows you to determine the age of this complex by the Early Neolithic. Modern software for 3D modeling and visualization opens up great opportunities, so a virtual method was chosen to reconstruct the appearance of a human from a burial. First, all the bones of the skeleton were scanned, for which two types of 3D equipment were used: a stationary scanner RangeVision Spectrum based on structured light photogrammetry (for the skull and small bones) and a hybrid handheld scanner with structured LED and infrared illumination Shining 3D Einscan H (for large bones). The scan results are processed in RangeVision's ScanCenter NG using built-in algorithms. Filling voids, smoothing surfaces, simplifying 3D models, and correcting mesh defects are done manually at the stage of model postprocessing. For further work, the resulting models were transferred to the stl format. Facial reconstruction was carried out in Blender and ZBrush in several stages: 1) importing and combining models; 2) modeling of lost teeth and reconstruction of the occlusion; 3) CAD modeling of a set of soft tissue depth markers and their positioning by craniometric points; 4) modeling of auxiliary circuits for nose reconstruction and eyeball setting; 5) modeling of masticatory muscles; 6) modeling of facial muscles and fat sacs to simplify the production of a basic head model; 7) modeling the base mesh of the head; 8) digital sculpting of the head; 9) detailing of the digital sculpture; 10) rendering of the model and preparing the model for printing. As a result, a digital model of the appearance of an Early Neolithic hunter-gatherer from a burial at the Shumilikha cemetery was obtained.
Chronology of the Pleistocene Finds of Homo Remains in Siberia: Results and Problems (A Short Overview)
Authors:   Sobolev Institute of Geology and Mineralogy SB RAS, Kuzmin Y. V.
Published: January 2023

This overview article contains a brief critical analysis of the chronology of Late Pleistocene and Early Holocene finds of Homo remains in Siberia. Direct dating of the Homo bones and teeth, as well as the isolation and analysis of the ancient human DNA, has now become firmly established in the practice of paleoanthropological research. About 62% of the Late Pleistocene and Early Holocene Siberian Homo remains have information on ancient DNA and direct dates of the bones and teeth. Particular attention is given to the assessment of the reliability of ages determined by the radiocarbon dating method. Information on the taphonomy (conditions and process of burial and fossilization) of Homo remains in the caves of the Mountain Altai is also of great importance. At present, three species of Pleistocene Homo are known in Siberia: Denisovans, Neanderthals, and anatomically modern humans (Homo sapiens). For the DenisovanNeanderthal hybrid, there is a direct date obtained by the Uranium series method, which shows the age of 67,500 cal BP. The age of other Denisovan fossils cannot be precisely determined due to the significant mixing of layers in Denisova Cave. The timing of the Denisovans in Siberia can be preliminarily determined at 130,000–44,000 cal BP (the upper limit is very approximate). The age of Siberian Neanderthals is greater than 50,000 cal BP; it is difficult to be more precise due to the widespread disturbance of the Altai caves’ stratigraphy by the burrowing activity of animals, primarily cave hyenas. Early Homo sapiens inhabited Siberia from 45,000 cal BP to the Early Holocene. No clear correspondence can be observed between climate changes in the second half of the Late Pleistocene (45,000–12,000 cal BP) and the chronology of Homo sapiens in Siberia. The age of some Homo sapiens fossils (Baigara, Solovyinaya Luka, and Sibiryachikha 6) after direct dating turned out to be much younger than initially expected. The taxonomic status of some Siberian Homo (Tuyana; an individual from the Okladnikov Cave with a date of 28,300 cal BP) has not yet been reliably identified. Obviously, it is necessary to increase the number of direct dates for Siberian hominins.
Female Figurines of the Kostenki Type: Style and Image
Authors:   Independent Researcher, Belyaeva V. I.
Published: January 2023

The paper considers 15 figurines from the Kostenki 1, Avdeevo, Gagarino, and Willendorf sites. For comparison, representations of two modern female figures are employed. In eight cases, we used copies of the statuettes (collection St Petersburg State University) for interpretation of the measurements. In other cases, published drawings and photographs were used. The ratios between the main parts of the body were not so unconditional it seemed before. The shins were reduced in size, but in five cases they corresponded to the norm. The head was too large at the Kostenki and Gagarino figurines and too small at the Avdeevo and Gagarino figurines. The heads of large Avdeevo figurines had absolutely correct proportions. All Kostenki figurines have a significantly enlarged body and torso, but Gagarino and Avdeevo images are more diverse. Deliberately enlarged pelvis, breasts, and abdomen required large torsos. The body weight of Kostenki figurines corresponds to modern standards, but Gagarino's is extremely increased. Avdeevo images are more diverse. The breasts are equally elongated and presented in two or three positions. The area of the pelvis and back is almost equal in proportion, stylistically it is presented in different variants in Kostenki and Gagarino. Avdeevo also shows great diversification. With all the diversity of the style of images, extremely similar forms are presented. As follows from well-known examples, the figurines depict women of different physiques. And they are on each group of sites. The pose of figurines is an extremely important element of their functional purpose. The line of the center of gravity does not coincide with the vertical position of the figure. The fuzzy position of the legs speaks, rather, of a lying posture of the depicted woman. Perhaps the figurines were supposed to be held in the palm, which corresponds to the size and shape of the figurines. Women’s figurines of the Kostenki Type were manufactured by professional artisans skilled in removing all the superfluous and highlighting the most essential. In our case it is an attempt to express the essence of the female principle in its figurativeness and variability.
Book Review Cynical Theories: How Activist Scholarship Made Everything About Race, Gender, and Identity—and Why This Harms Everybody
Authors: Kumar Rahul
Published: January 2023

Review of Pluckrose, H., & Lindsay, J. (2020). Cynical theories: How activist scholarship made everything about race, gender, and identity—and why this harms everybody.
AKTIVITAS PERCOBAAN MENANAM HIDROPONIK BERBASIS PENDEKATAN HEUTAGOGY BAGI SISWA SEKOLAH DASAR
Authors: Gunansyah Ganes , Suprayitno Suprayitno , Damayanti Maryam Isnaini , Subrata Heru
Published: January 2023

Student learning activities carried out online during the Covid-19 pandemic, in addition to providing convenience, also impact the increasingly limited practice of activity-based learning oriented to produce products/works. Overcoming these obstacles, among others, can be facilitated through simple experimental practice activities to plant hydroponic plants to facilitate independent learning, creativity, and collaboration of students with parents. This community service activity was packaged through online training through the Zoom web meeting platform for three sessions, including training material presentation sessions, independent practice of hydroponic planting experiments with the wick system technique, and reflection and follow-up plans. This activity was attended by Elementary School (SD) students and their assistants spread across three Cities/Regencies in East Java, including Surabaya City and Sidoarjo Regency. Participants in this activity are urban communities with limited land, so they are technically suitable for hydroponic planting activities. The experimental practice phase was carried out starting from seeding to nurseries by utilizing training packages in starts and hydroponic planting assistance modules. During the training preparation, implementation and evaluation, participants showed high enthusiasm. Based on the reflection and follow-up of this activity, it is constructive to develop independent learning and collaboration between students and parents. It can be an alternative activity to be applied at home in the surrounding environment and school during the pandemic.
PELATIHAN SENI KARAWITAN DALAM RANGKA PELAYANAN KEPADA LANJUT USIA DI PERSATUAN WREDATAMA REPUBLIK INDONESIA (PWRI)
Authors: Sabri Indar , Winarko Joko , Trisakti Trisakti , Rahayu Eko Wahyuni , Karoso Subiyanto
Published: January 2023

Peningkatan jumlah penduduk lanjut usia ini tidak hanya terjadi pada setiap kelompok masyarakat. Hal ini juga terjadi pada para pensiunan, yang sekarang tergabung dalam organisasi Persatuan Wredatama Republik Indonesia (PWRI) di Kecamatan Tandes. Nasib para pensiunan seringkali mengalami rasa bosan terhadap kegatan organisasi yang monoton dan menambah beban penderitaan bagi mereka dalam menikmati hari tua. Sehingga perlu adanya kegiatan yang dapat dijadikan sebagai semangat dalam menjalani hidup yang berkualitas.

Persatuan Wredatama Republik Indonesia (PWRI) Kecamatan Tandes mempunyai kebijakan khusus untuk memberi pelayanan yang berkualitas serta menjunjung tinggi harkat dan martabat para lanjut usia khususnya bagi para pensiunan. Dampak dari keberhasilan pelayanan sosial salah satunya adalah memberi pengaruh terhadap peningkatan usia harapan hidup kepada para pensiunan di Kota Surabaya.

Sebagian besar dari para penghuni di Persatuan Wredatama Republik Indonesia (PWRI) Kecataman Tandes memiliki keinginan untuk dapat melakukan aktivitas kesenian sebagai pembangkit rasa semangat dan sekaligus interaksi yang menghibur kepada sesama para penghuni. Berangkat dari hal inilah maka tim Pengabdian Kepada Masyarakat Jurusan Sendratasik Fakultas Bahasa dan Seni Universitas Negeri Surabaya melakukan kerja bersama dengan Persatuan Wredatama Republik Indonesia (PWRI) Kecamatan Tandes untuk melakukan program pelatihan seni kesenian yang difokuskan dalam jenis seni karawitan. Kegiatan penyajian karawitan baik tembang ataupun alunan gending dapat menghibur dan membangkitkan semangat untuk hidup yang berkualitas.
Relaciones interpersonales en la convivencia escolar
Authors: Bonozo Medina Delia Carolina , Merchán González Jenny Alexandra , Guapi Mullo Fanny Janneth , Toala Franco Irma Priscila
Published: January 2023

En la década de los 90s el tema de “convivencia escolar” emergió como una perspectiva prometedora para abordar una problemática relativa a la vida compartida en las escuelas, dentro del desarrollo integral del estudiante relaciones interpersonales juegan un papel muy importante en su formación, adaptación social, rendimiento educativo y proceso de integración educativa. La metodología utilizada para el presente trabajo de investigación, se enmarcada dentro de una revisión bibliográfica de tipo documental, ya que nos vamos a ocupar de temas planteados a nivel teórico como es Relaciones interpersonales en la convivencia escolar. La forma cambiante tanto de las instituciones educativas como lugares donde se producen aprendizajes. La técnica para la recolección de datos está constituida por materiales electrónicos, estos últimos como Google Académico, entre otros, apoyándose para ello en el uso de descriptores certificados y avalados por el tesauro de la UNESCO. La información aquí obtenida será revisada para su posterior análisis. La convivencia escolar es muy importante dentro del desarrollo social del estudiante, y más en el contexto del tiempo, es decir, las horas que pasan los estudiantes en las aulas de clase y que permiten esa interacción, sin embargo, el estudiante debe tener sólidas bases morales que se inculcan en el entorno familiar y que luego son reforzados en la escuela, los ambientes familiares sanos, una escuela con valores y estándares de calidad que fomenten las relaciones e integraciones escolares, también ayudan mucho en una libre y sana convivencia.
Lesiones dermatológicas post y durante Covid 19
Authors: Vaca Pino Ximena Katherine , Cedeño Arcentales Jessica Yuleidy , Ramírez Segarra Gladys Assenneth , Oñate Flores Carlos Ricardo
Published: January 2023

El compromiso cutáneo es una cuestión rara y emergente en la COVID-19, que puede acompañar o preceder a los síntomas clínicos. Los pruritos cutáneos asociados a la COVID-19 pueden ser erróneamente diagnosticados a nivel clínico, al igual que otras dermatosis no asociadas. Por tanto, es prudente que los dermatólogos y médicos de atención primaria sean conscientes de las manifestaciones cutáneas de la COVID-19, a fin de prevenir los diagnósticos erróneos y la pérdida de casos cuando el compromiso cutáneo precediera a otros síntomas. La metodología utilizada para el presente trabajo de investigación, se enmarca dentro de una revisión bibliográfica de tipo documental, ya que nos vamos a ocupar de temas planteados a nivel teórico como es Lesiones dermatológicas post y durante Covid 19. La técnica para la recolección de datos está constituida por materiales electrónicos, estos últimos como Google Académico, PubMed, Science direct, entre otros, apoyándose para ello en el uso de descriptores en ciencias de la salud o terminología MESH. La información aquí obtenida será revisada para su posterior análisis. Actualmente a casi 3 años de la declaración oficial por parte de la Organización Mundial de la Salud del Covid 19 como pandemia mundial, ya existen evidencias de que, si pueden generarse enfermedades o lesiones dermatológicas durante el proceso o después de haberse contagiado, sin embargo, con los tratamientos adecuados, la mayoría de los casos en pocas semanas se resuelven y desaparecen estas lesiones.
Traquipnea transitoria del recién nacido
Authors: Peña Sornoza Kevin Jair , Chancay Marcillo Lady Maena , Cevallos Mendoza Gema Monserrate , Mendoza Macías Johanna Marisela
Published: January 2023

La taquipnea transitoria del recién nacido (TTRN), conocida también como retraso de la eliminación del líquido pulmonar. A pesar de ser un proceso benigno requiere el ingreso del recién nacido y, en algunos casos, se asocian complicaciones, además hay estudios que sugieren que la TTRN incrementa el riesgo del neonato a desarrollar sibilancias en la primera infancia. Los recién nacidos prematuros, y/o en aquellos que nacen sin trabajo de parto previo, no tienen oportunidad de eliminar tempranamente el líquido pulmonar, por lo que comienzan su vida extrauterina con un exceso de líquido en sus pulmones. A través de una metodología descriptiva se realiza un estudio bibliográfico de los aportes académicos significativos que aportan a la construcción global de conocimiento y actualización de la Traquipnea Transitoria Neonatal. La investigación sugiere que para prevenir la traquipnea transitoria neonatal es necesario disminuir la incidencia de partos por cesárea. Paradójicamente las cesáreas electivas han ido en aumento también por un tema preventivo de complicaciones en el embarazo de la población femenina y la salud del recién nacido. Sin embargo, ahora se recomienda plantearlas cumplidas al menos 39 semanas de gestación o en el mejor de los casos esperar que comience el trabajo de parto. Los ensayos clínicos han demostrado que una buena oxigenación revierte la vasoconstricción del lecho vascular pulmonar disminuyendo la resistencia vascular pulmonar, aumentando el flujo del pulmón y se logra a través de la Administración de oxígeno, la Asistencia Ventilatoria, Terapia con Salbutamol Inhalado y la Restricción de líquidos son las medidas de tratamiento efectivas para superar efectivamente la TTN.
Transformation of Architecture of Rumoh Aceh: An Encoding Process Through Semiotic
Authors: Putra Riza Aulia , Ekomadyo Agus Suharjono
Published: January 2023

Rumoh aceh is a Acehnese traditional house which is one of the products and artifacts of the Acehnese culture. Efforts to preserve rumoh aceh often focus on physical aspects or aspects of form that are seen directly. This has led to the discovery of many new buildings that adopt the architectural form of rumoh aceh directly without a more comprehensive elaboration and transformation process. A concerted effort is required to present rumoh aceh architecture in a modern context. Transformation is one of the methods in architectural design to be able to present new ideas that are creative and innovative. The transformation in this paper is obtained through an encoding process that employs a semiotic approach as a method for bridging the rumoh aceh architecture transformation process. The encoding process is carried out by reinterpreting the values of rumoh aceh architecture obtained from previous research. The aim of this paper is to gain knowledge regarding the architectural design process that can present a creation that represents regional culture, in this case to present rumoh aceh architecture in a modern context.
COVID-19 mortality attenuated during widespread Omicron transmission, Denmark, 2020 to 2022
Authors: Friis Nikolaj U , Martin-Bertelsen Tomas , Pedersen Rasmus K , Nielsen Jens , Krause Tyra G , Andreasen Viggo , Vestergaard Lasse S
Published: January 2023

Background

It sparked considerable attention from international media when Denmark lifted restrictions against COVID-19 in February 2022 amidst widespread transmission of the new SARS-CoV-2 Omicron variant and a steep rise in reported COVID-19 mortality based on the 30-day COVID-19 death count.

Aim

Our aim was to investigate how coincidental infections affected COVID-19 mortality estimates following the introduction of the Omicron variant in late 2021.

Methods

We compared the 30-day COVID-19 death count with the observed mortality using three alternative mortality estimation methods; (i) a mathematical model to correct the 30-day COVID-19 death count for coincidental deaths, (ii) the Causes of Death Registry (CDR) and (iii) all-cause excess mortality.

Results

There was a substantial peak in the 30-day COVID-19 death count following the emergence of the Omicron variant in late 2021. However, there was also a substantial change in the proportion of coincidental deaths, increasing from 10–20% to around 40% of the recorded COVID-19 deaths. The high number of 30-day COVID-19 deaths was not reflected in the number of COVID-19 deaths in the CDR and the all-cause excess mortality surveillance.

Conclusion

Our analysis showed a distinct change in the mortality pattern following the introduction of Omicron in late 2021 with a markedly higher proportion of people estimated to have died with, rather than of, COVID-19 compared with mortality patterns observed earlier in the COVID-19 pandemic. Our findings highlight the importance of incorporating alternative mortality surveillance methods to more correctly estimate the burden of COVID-19 as the pandemic continues to evolve.
Overdispersion Models for Clustered Toxicological Data in a Bioassay of Entomopathogenic Fungus
Authors: Freitas Silvia Maria de , Fallah Lida , Demétrio Clarice G. B. , Hinde John P.
Published: January 2023

We consider discrete mortality data for groups of individuals observed over time. The fitting of cumulative mortality curves as a function of time involves the longitudinal modelling of the multinomial response. Typically such data exhibit overdispersion, that is greater variation than predicted by the multinomial distribution. To model the extra-multinomial variation (overdispersion) we consider a Dirichlet-multinomial model, a random intercept model and a random intercept and slope model. We construct asymptotic and robust covariance matrix estimators for the regression parameter standard errors. Applying this model to a specific insect bioassay of the fungus Beauveria bassiana, we note some simple relationships in the results and explore why these are simply a consequence of the data structure. Fitted models are used to make inferences on the effectiveness and consistency of different isolates of the fungus to provide recommendations for its use as a biological control in the field.
Application of activated zeolite "ZEOL" in feeding calves
Authors: Kashaeva Alia Rinatovna , Akhmetzyanova Firaya Kazbekovna , Shakirov Shamil Kasimovich , Sharafutdinov Gazimsan Salimovich
Published: January 2023

The article presents the results of the use of activated zeolite "ZEOL" in feeding calves of the dairy and post-dairy period. It has been shown that the addition of activated zeolite to calves' diets at a dose of 0.5 g / kg of live weight does not adversely affect the physiological state, metabolism in the body and the health of young animals in general. In the calves of the experimental group, an increase in live weight (by 5.6%), a reduction in feed costs per kg of increase (by 5.3%), high economic efficiency of feeding activated zeolite by 1 rub. of additional costs were established.
Ultrasonic technology processing of grain and leguminous crops
Authors: Morgunova Natalya Lvovna
Published: January 2023

When processing grain and leguminous crops, it is necessary to carry out preparatory operations consisting in washing, moistening and extraction. Existing technologies for processing grain and leguminous crops in small enterprises do not allow cleaning the grain surface in hard-to-reach places, and also have a long process of humidification and extraction. The article presents the design parameters of the plant for processing grain and leguminous crops, which significantly speed up the process of humidification, washing and extraction.
The analysis of Polish patent applications in the solar energy technology with the use of text mining methodology
Authors:   Kielce University of Technology, Faculty of Management and Computer Modelling, Bęben Karolina , Nowakowska Marzena ,   Kielce University of Technology, Faculty of Management and Computer Modelling
Published: January 2023

Purpose: Knowledge management belongs to the most important elements of organisational management, including manufacturing enterprises. Patent information plays an increasingly important role in this area. Identification of the main directions of invention activity may inspire new product and process ideas, and can help to improve existing solutions. The above is particularly important in the energy sector, which is currently struggling with increasing problems. In this context, solar energy is the subject of interest to inventive communities. The paper discusses patent applications related to solar energy, taking up the task of discovering the main tendencies of technological solutions in this area. Design/methodology/approach: In the work, a pilot study of the research aimed to indicate the directions of technological development in the field in Poland was undertaken. Shortened descriptions of selected patent documents from the Polish Patent Office (PPO) were the subject of the investigation. The descriptions were reduced to the form of a vector space model by using text mining tools. The exploration of such prepared data was done applying unsupervised text mining techniques. Hierarchical cluster analysis enabled the identification of groups of similar inventions. An algorithm to detect outliers within individual patent groups was also developed and applied. Findings: Five patent clusters were identified covering the following thematic areas: PV panel designs, PV panel component designs, the improvement of solar-heat conversion device performance, and solar collector designs. Six patent applications stood out thematically in four of the five clusters. Research limitations/implications: The research is limited to a selected number of patent documents form PPO. However, the presented method and research area are promising. It is planned to extend the analyses to a larger set of patent documents and solve the problem related to the language uniformity of patent applications along with merging data from various sources. In this aspect, a full patent description will be consider as well. Keywords: solar energy patent analysis, patent documents processing, patent clustering, outliers detection, Polish Patent Office. Originality/value: In relation to solar energy issues, main patent areas and patent outliers that may be indicators of special interests of inventors were identified. In relation to methodology issues, new solutions within consecutive research steps were proposed.
Prevention of threats from the area of food defence and food fraud on the example of the sushi&food factor company
Authors:   Poznań University of Economics and Business, Institute of Management, Górna Justyna , Brzechwa Adam ,   Sushi&Food Factor, Kowalczyk Anna ,   Sushi&Food Factor
Published: January 2023

Purpose: The main purpose of this article was to present the actions taken by the company in the field of its food defence and food fraud. Design/methodology/approach: The article presents the approach used in the analyzed company to supervise the food defence and food fraud area. As part of the analysis, the applicable documents in the scope of the conducted risk analyzes were presented. The adopted methodology for the evaluation of raw materials and their suppliers in the food fraud area is based on the IFS guidelines, as well as an approach developed by the authors of this study, who participated in the implementation of this methodology in the company. Findings: The presented approach to supervision in the area of food defence and food fraud in the analyzed company ensures its continuous development depending on the changing environment and risk factors. The Sushi&Food Factor company is characterized by a high culture of safety and quality of the produced food. Actions are still being taken to support its development in various areas, such as communication, employee involvement, risk awareness. The activities used by the company related to the verification of the effectiveness of supervision over the areas of food defence and food fraud, such as the simulation of unauthorized access or the review and assessment of incidents that have currently occurred on the market, allow for the necessary preventive measures to be taken. Originality/value: The article presents a practical approach to the implementation of the requirements of standards in the area of food defence and food fraud. The article may be an element influencing the improvement of activities in the discussed areas in other enterprises, which may contribute to the development of their food safety and quality culture. Keywords: Food defence, food fraud, food safety. Category of the paper: Case study.