bluuebunny/crossref_metadata_2025 huggingface dataset:
Regional specialized scientific and educational cluster - educational continuum, innovative educational space for personalized and corporate education of health workers
Authors:   FGAU «NMITs» MNTK «Eye Microsurgery» named after A.I. acad. S.N. Fedorov» of the Ministry of Health of Russia, Krasnodar branch, Zabolotny A.G. ,   SBEI HE «Kuban State Medical University» of the Ministry of Health of Russia
Published: July 2022

The implemented project of the educational continuum is presented: Regional ophthalmic scientific and educational cluster, an independent organizational and functional structure based on the integration interaction of federal scientific medical and higher educational institutions of the Krasnodar Territory, a constituent entity of the Russian Federation, an effective structural and organizational form of professional and educational support for personalized and corporate postgraduate medical education.
New development trends in the department of additional professional education for specialists with a secondary pharmaceutical education: problems and prospects
Authors:   Pharmaceutical Branch of the State Budgetary Vocational Educational Institution «Sverdlovsk Regional Medical College», Samkova I.A. , Babikova E.A. ,   Pharmaceutical Branch of the State Budgetary Vocational Educational Institution «Sverdlovsk Regional Medical College»
Published: July 2022

The continuous development of the healthcare system requires constant professional improvement from the pharmaceutical industry specialists. For effective interaction with medical specialists and end users of medicines, pharmaceutical workers must be aware of current trends in the development of pharmacy. In this regard, educational organizations are organizing the work of additional professional education (AVE) departments according to new trends, actively implementing programs for the Continuing Medical and Pharmaceutical Education portal of the Russian Ministry of Health (CME portal). The material presents an analysis of the work of the APE Department of the Pharmaceutical Branch of the Sverdlovsk Regional Medical College, which identifies the most relevant areas for development related to the development of programs for the CME system. The difficulties of transition to the CME system for specialists with a secondary pharmaceutical education were also noted.
An Analytical Investigation of Flipped Classroom to Improve Saudi EFL Learners’ Speaking Skills: a Case Study at Applied College
Authors: Asaad Hamza Sheerah Hebah , Sharma Yadav Meenakshi
Published: July 2022

The flipped classroom strategy in the Saudi educational system is changing how we gather information, research, and share data with others. New technology tools are transforming the educational community and how instructors transmit information to students. With this new tool, the flipped classroom technology method is being used on a bigger scale at most academic levels, particularly in Saudi Arabia. This study investigated the flipped classroom method (FCM), i.e., hybrid-flexible and hyflex models based on tri-model teaching approaches, to enhance the speaking skills of EFL students at Applied College for Girls, King Khalid University, at college level, and identify students’ opinions and responses towards the strategies used by the instructors. This research answered the following questions significantly: (i) What are EFL students’ opinions about their English speaking skills? (ii) To what extent does mixing FCM affect EFL students’ speaking skills? (iii) what are the EFL students’ opinions about integrating FCM into speaking lessons? A quasi-method was adopted to collect the control (N = 32) and the focused (N = 24) groups’ data. Two sets of opinion and satisfactory questionnaires were sent to the students to gain their opinions on learning the speaking skill, including the teacher’s observation to perceive the methodology and the instruments used to access speaking during the study. Finally, a focused group interview was conducted to ascertain the students’ satisfaction and homogeneous proficiency level in fulfilling the aims of adopting the flipped classroom approach. After one semester (13 weeks) of intervention, the outcomes revealed the significant overview that the students appreciated and found the FCM adequate in being more fluent, confident, and competent in their production classes. The findings might provide other valuable information for researchers involved in EFL advanced pedagogy to explore the operative speaking teaching method and module.
Improving the shapes of planar antenna arrays to improve accuracy of radar with super-resolution
Authors: Nechaev Yury Borisovich , Peshkov Ilia Vladimirovich , Fortunova Nataliya Alexandrovna , Zaitseva Irina Nikolaevna , Arnautov Eugene Alexandrovich
Published: July 2022

A promising way to increase the bandwidth and noise immunity of modern wireless information transmission systems is the use of antenna arrays equipped with a digital signal processing unit, which include MIMO systems (Multiple Input Multiple Output), as well as adaptive (smart) antennas. The main advantage of this approach is the antenna’s spacing, which makes it possible to assess the angular coordinates of radio signals with further developing

a radiation pattern. Gaps in studying the influence of the lattice geometry together with various kinds of antenna elements are known to be one of the factors of inaccuracy of such systems. The work is aimed at obtaining the shape

of a planar antenna array with a higher direction finding accuracy. There is described an algorithm for calculating such an arrangement of antenna elements of flat antenna arrays, in which the standard deviation of the estimates of the angular coordinates of one and two radio signal sources is reduced. The proposed approach is based on the analysis

of the influence of antenna location on the variance of estimates described by the lower boundary of Kramer-Rao. This value shows the influence of the location of antenna elements on the accuracy of estimating the direction of arrival of a joint assessment with two signal sources. It has been shown that the accuracy of the direction-of-arrival non-joint estimation is determined as the sum of squared differences between all coordinates of omnidirectional elements along the X- and Y-axis if one signal arrives. If two signals arrive, the accuracy of the direction-of-arrival joint estimation depends on the sum of cosines having the argument with the difference between sensor coordinates and signals radius-vectors. The optimal location of the antenna elements using the obtained expressions can be calculated very easily to reduce the direction-finding errors near particular sectors. In order to confirm the proposed method, there were studied the antenna arrays built after minimizing the boundary of Kramer-Rao, where the target functions are the new expressions. It is found out that the new shapes of antenna arrays based on the analytical expressions have better direction-of-arrival accuracy in comparison with the circular ones.
Developing e-learning course for information security specialists
Authors: Sibikina Irina Vyacheslavovna , Kuchin Ivan Yurevich , Shikhbabaeva Karina Abdulnasirovna
Published: July 2022

Improving the quality of organizing the educational process and ensuring training of the qualified specialists are the leading tasks of the modern education system in Russia. An important condition for solving these problems is to expand the practice and use of innovative forms of education and the introduction of information pedagogical technologies. EdTech (Education Technology) develops rapidly in Russia: the number of people who completed various online courses has increased almost 3 times (from 14.5 to 41.3%) in 2021, more than 18 million people received online education, among them more than 2.5 million people have mastered different IT professions, and spending on online education over the past 12 months amounted to 226 billion rubles. Informatization of the education system entails a rapid increase in some developed electronic educational resources, e-learning systems and e-learning courses. Analysis of the e-learning effectiveness was carried out, modern Russian e-learning systems and their foreign counterparts were analyzed, a proper e-course was created on the base of the LMS Moodle platform, which is adaptable to the conditions of the educational process in the disciplines of higher educational institutions and schools. The electronic resources have been classified and the most successful combination of them in a training course for the successful solution of modern educational problems has been identified. The importance of using LMS and LCMS e-learning systems is stated, which is the best option for use in higher education institutions thanks to automated learning management, remote access to educational content, scalability and flexibility of the learning management system. The development of an electronic training course contributes to the effective and high-quality training of specialists in the field of information security.
Place Attachment Assessment through the Lens of Territorial Identity: The Town of Oraviţa as a Case Study (Romania)
Authors:   University of Bucharest, Faculty of Geography, Department of Human and Economic Geography, Interdisciplinary Center of Advanced Research on Territorial Dynamics, Bucharest, ROMANIA, MERCIU Florentina-Cristina , OLARU Martin ,   University of Oradea, Faculty of Geography, Tourism and Sport, Doctoral School, Oradea, ROMANIA, MERCIU George-Laurenţiu ,   University of Bucharest, Faculty of Geography, Bucharest, ROMANIA
Published: July 2022

This study focuses on the analysis of place attachment related to the elements of territorial identity in Oraviţa, a small town in the Mountainous Banat. Oraviţa played a highly significant role from an economic and administrative point of view during the Austrian domination: it was the urban centre that coordinated the mining activity on the territory of Mountainous Banat. This study aims to assess the place attachment to several symbolic buildings in Oraviţa that have been identified as elements of territorial identity. In order to fulfil the purpose of this study, the following research questions were established: What are the main elements of territorial identity in Oraviţa represented in postcards over time? Which of the identified elements of territorial identity are currently being promoted and valued by the local public administration? What are the elements of territorial identity of Oraviţa to which the population is attached? From a methodological point of view, the authors used postcards to identify the elements of territorial identity. Subsequently, the place attachment to the representative historical buildings of Oraviţa was interpreted based on the analysis of the information posted on sites developed by members of the local community. In conclusion, the authors highlighted the particular characteristics of the urban fabric of Oraviţa and their various ways of use, elements through which the physical and social attachment of the local population were preserved.
"Discovering the City of Lodz (Poland). Spatial Experiences and Perceptions of Exchange Students "
Authors:   University of Lodz, Faculty of Geographical Sciences, Department of Regional and Social Geography, Lodz, POLAND, TOBIASZ-LIS Paulina
Published: July 2022

This paper aims to reveal the process of adapting to a new environment and developing perceptions of the city of Lodz, Poland by its temporary users – exchange students, studying at the local university. The data analysed and interpreted here was collected during lectures and workshops on Mental Maps and Images in Geography conducted at the Faculty of Geographical Sciences, the University of Lodz, between 2021 and 2022, using sketch maps, photographic essays and digital story maps prepared by course participants. The study tests those tools’ usefulness in recognising the relationship between a person and the surrounding space. Results framed by the concept of three-folded spatiality show that during 3-4 months of their stay in Lodz, along everyday direct spatial experiences as well as indirect interactions with the city, when learning about it in the classroom, reading or talking to people, exchange students gain a wide understanding of Lodz, and the initial sense of alienation gives way to emotional reactions and place attachment. The research presented in this paper is framed by the cultural approach in urban geography making the concept of imagined and lived spaces central and in a wider perspective, using constructionist methodology in social sciences. It aims to follow patterns of transforming the new, undiscovered space into a set of individually experienced and defined places filled with the emotions of exchange students, evolving their new local identities and place attachment. The study can impact future local planning to maximise the exchange students’ satisfaction as agents of urban improvement.
Adecuaciones bioclimáticas para un edificio de investigación-docencia en la Universidad Autónoma Metropolitana, Unidad Azcapotzalco
Authors:   , Avelar Juárez Eder
Published: July 2022

Ante la problemática ambiental a la que nos enfrentamos en la actualidad surgen varias disciplinas que tienen por objetivo el desarrollo de métodos y tecnologías para lograr una mejor integración del ser humano con el ambiente. El presente trabajo aborda La Arquitectura Bioclimática como una de esas diciplinas, donde se aplicaron varios de sus conceptos y técnicas con la finalidad de mejorar el espacio arquitectónico de una edificación académica y de investigación al interior de una institución superior de educación. La primicia del trabajo fue realizar un estudio de lo general a lo particular, comenzado con un análisis climático de la zona donde se ubica la edificación, hasta la determinación de las necesidades de confort específicas de cada uno de los espacios que conforma el edificio, de tal modo que se pudieran ofrecer las mejores adecuaciones y/o soluciones arquitectónicas, en función de aprovechar de la mejor manera el recurso natural incidente al edifico, propia de la zona.
El paisaje metropolitano de Pachuca de Soto, Hidalgo, México. Su revaloración y puesta en valor a través del análisis de sus Unidades Formales de Paisaje y Patrimonio
Authors:   , Sánchez Roldán María Elena
Published: July 2022

La presente tesis se realizó analizando la Zona Metropolitana de Pachuca, en el Estado de Hidalgo, México. El problema detectado es la falta de conocimiento acerca de los valores presentes en su paisaje y lo que ellos significan, por lo que es necesario identificar, mostrar y revalorar los elementos componentes de su paisaje, para su posible puesta en valor. Esta investigación se fundamenta en el Marco Teórico analizando los conceptos de paisaje, bajo la mirada de George Simmel, August Berque y Javier Maderuelo; de patrimonio, consultando a Françoise Choay; de valores a Alois Riegl y Jukka Jokilehto y conservación, a Ignacio González Varas. En el Marco Normativo se analiza la legislación en torno al paisaje en México, tomando en cuenta la opinión de Martín Checa Artasu y Alonso Navarrete. En el Marco Metodológico, se analizan las metodologías europeas y latinoamericanas para la valoración del paisaje, del que se destaca el método de análisis de la Metropolitan Existing Situation Analysis (MESA), creado por el programa “Training for Education, Learning and Leadership Towards a New Metropolitan discipline TELLme, analizado en conjunto con el equipo docente del posgrado de Diseño, Planificación y Conservación de Paisajes y Jardines de la Universidad Autónoma Metropolitana, Unidad Azcapotzalco. Se atienden tres propósitos principales: 1) Se identifican y reconocen a través de la investigación historiográfica los elementos componentes y atributos que han estado presentes en la trayectoria de la actual Zona Metropolitana de Pachuca (ZM-P). 2) Se muestran los resultados referentes a los valores presentes en el paisaje de la ZM-P, mismos que a través de la metodología construida para este estudio, son utilizados para definir las Unidades Formales de Paisaje y Patrimonio (UFPP). 3) Se muestra la relevancia de las UFPP en la ZM-P como instrumento de planeación, fundamental para la realización de proyectos integrales. Para ello se eligió un paisaje de atención especial, detectado en la UFPP Distrito Minero Pachuca Real del Monte, en el cual se proponen dos tipos de Recorridos con Valor Histórico: Recorridos Naturalmente Sanos y Recorridos Urbanos con Sabor Minero, con la intención de mejorar la calidad paisajística de la zona, así como su reconocimiento como paisaje minero, mismo que ha quedado registrado como un hecho cultural, por lo que debe ser valorado por la población para poder apropiarse de él, a través de su percepción integral; con miras a su consolidación como Patrimonio Cultural.
Meditação, ansiedade e qualidade de vida em minorias sexuais
Authors: Francisco Leilane Camila Ferreira de Lima , Barros Alice Correia , Magalhães Ana Paula Nogueira , Albuquerque Joelma de Oliveira , Maia Ana Claudia Corrêa de Ornelas , Alves Verônica de Medeiros
Published: July 2022

O objetivo deste estudo foi avaliar o efeito da meditação na ansiedade e na qualidade de vida em minorias sexuais e de gênero. Trata-se de um ensaio clínico randomizado, 23 indivíduos participaram do grupo experimental e 19 do controle. Houve diminuição das médias de ansiedade estado, ao se comparar o pré-teste (51,87±10,20) com a 4ª semana (42,70±12,85) e a 8ª semana de meditação (41,12±14,02) no grupo experimental (ρ = 0,015). Não houve efeito estatisticamente significativo da meditação na qualidade de vida, apesar dessa média ter aumentado durante a prática. A meditação pode ser uma estratégia de cuidado de enfermagem em saúde mental.

Descritores: Meditação, Saúde Mental, Minorias Sexuais e de Gênero.

 

Meditation, anxiety and quality of life in sexual minorities

Abstract: The aim of this study was to evaluate the effect of meditation on anxiety and quality of life in sexual and gender minorities. This is a randomized clinical trial, 23 individuals participated in the experimental group and 19 in the control. There was a decrease in the averages of state anxiety, when comparing the pre-test (51.87±10.20) with the 4th week (42.70±12.85) and the 8th week of meditation (41.12±14, 02) in the experimental group (ρ = 0.015). There was no statistically significant effect of meditation on quality of life, although this mean increased during practice. Meditation can be a nurse mental health care strategy.

Descriptors: Meditation, Mental Health, Sexual and Gender Minorities.

 

Meditación, ansiedad y calidad de vida en minorías sexuales

Resumen: El objetivo de este estudio fue evaluar el efecto de la meditación sobre la ansiedad y la calidad de vida en minorías sexuales y de género. Este es un ensayo clínico aleatorizado, 23 individuos participaron en el grupo experimental y 19 en el control. Hubo una disminución en los promedios del estado de ansiedad, al comparar el pre-test (51.87 ± 10.20) con la 4a semana (42.70 ± 12.85) y la 8a semana de meditación (41.12 ± 14, 02) en el grupo experimental (ρ = 0,015). No hubo un efecto estadísticamente significativo de la meditación sobre la calidad de vida, aunque esta media aumentó durante la práctica. La meditación puede ser una estrategia de atención de enfermería de salud mental.

Descriptores: Meditación, Salud Mental, Minorías Sexuales y de Género.
Atendimento de enfermagem ao portador de doença de Fabry: relato de experiência
Authors: Lacerda Rosiane Cássia Teixeira , Barros Luciene de Fátima Neves Monteiro de
Published: July 2022

A doença de Fabry é uma doença de origem genética ligada ao cromossomo X. Ocorre devido a um erro inato no metabolismo dos glicoesfigolipídeos, o que provoca a deficiência da enzima alfa-galactosidase A. O diagnóstico de Doença de Fabry na maioria das vezes é desafiador. Desta forma, a atuação do enfermeiro no processo saúde doença do paciente com a Doença de Fabry é indispensável na educação e direcionamento do tratamento adequado frente às complicações e o agravamento da sua doença. Trata-se de um estudo descritivo, tipo relato de experiência, elaborado no contexto da experiência vivida durante o atendimento de enfermagem ao Paciente portador de Doença de Fabry, que tem como objetivo principal a orientação e direcionamento na realidade vivida pelos pacientes e as dificuldades encontradas durante a jornada em busca de atendimento e acesso ao tratamento.

Descritores: Doença de Fabry, Enfermagem, Alfa-Galactosidase.

 

Nursing care for patients with Fabry disease: experience report

Abstract: Fabry disease is a disease of genetic origin linked to the X chromosome. It occurs due to an inborn error in the metabolism of glycosphygolipids, which causes the deficiency of the enzyme alpha-galactosidase A. The diagnosis of Fabry Disease is often challenging. . In this way, the role of nurses in the health-disease process of patients with Fabry Disease is essential in educating and directing the appropriate treatment in the face of complications and the worsening of their disease. This is a descriptive study, type of experience report, elaborated in the context of the experience lived during the nursing care to the patient with Fabry Disease, which has as main objective the orientation and direction in the reality lived by the patients and the difficulties encountered. during the journey in search of care and access to treatment.

Descriptors: Fabry Disease, Nursing, Alpha-Galactosidase.

 

Cuidados de enfermería a pacientes con enfermedad de Fabry: relato de experiencia

Resumen: La enfermedad de Fabry es una enfermedad de origen genético ligada al cromosoma X. Se produce debido a un error congénito en el metabolismo de los glucoesfigolípidos, lo que provoca la deficiencia de la enzima alfa-galactosidasa A. El diagnóstico de la enfermedad de Fabry suele ser un reto. De esta forma, el papel del enfermero en el proceso salud-enfermedad de los pacientes con Enfermedad de Fabry es fundamental para educar y orientar el tratamiento adecuado ante las complicaciones y el empeoramiento de su enfermedad. Se trata de un estudio descriptivo, tipo relato de experiencia, elaborado en el contexto de la experiencia vivida durante el cuidado de enfermería al paciente con Enfermedad de Fabry, que tiene como principal objetivo la orientación y dirección en la realidad vivida por los pacientes y las dificultades encontradas. .durante el viaje en busca de atención y acceso al tratamiento.

Descriptores: Enfermedad de Fabry, Enfermería, Alfa-Galactosidasa.
Presence of Rotavirus and Astrovirus in Employees, Tools and Equipment of Slaughterhouses and Meat Processing Plants
Authors: YALÇIN Halil , KALE Mehmet , GÜRSOY Oğuz , SALTIK Hasbi Sait , YILMAZ Yusuf
Published: July 2022

Rotavirus and astrovirus are two important foodborne pathogens for humans. This study was aimed to investigate the presence of viruses in four slaughterhouses. In the study, swab samples were obtained from both hands of sixty butchers working in slaughterhouses and different sections of meat processing plants and twenty-nine tools and equipment used in slaughterhouses to determine rotavirus and astrovirus antigens by ELISA. Personnel interviews were also held with the butchers to obtain information regarding their gender, age, education level, hygiene training, smoking status, habits of glove use during working as well as whether they had digestive problems in the period of study. Results of swab analyses indicated that rotavirus antigen was found in a butcher of a slaughterhouse. There was no rotavirus antigen in any tool and equipment used in slaughterhouses. Also, there was no astrovirus antigen in neither employee nor tool and equipment. Results showed that there was a risk of rotavirus contamination from personnel working in slaughterhouses where general hygiene rules were not fully implemented. It can be concluded that personal health consciousness and hygiene practices before and during working in a slaughterhouse are crucial for personnel protection against rotavirus or astrovirus infections.
Doğal Killerin Model Yağın Renk ve Fiziko-kimyasal Özellikleri Üzerine Etkisi
Authors: DEMİR Didem , GÜN Zeynep , YILMAZ Emin
Published: July 2022

Bu çalışmanın amacı, beta karoten ve klorofil katılarak hazırlanan model yağdan bu pigmentlerin verdiği rengin uzaklaştırılma kapasitelerinin 9 doğal kil ve 2 ticari ağartma toprağı (T.A.T.) açısından karşılaştırılmasıdır. Halloysit, zeolit, bentonit, sepiyolit, diatom toprağı, Magnesol XL, kaolin, montmorillonit ve perlit model yağa ağırlıkça %0.5 oranında katılmış ve 80°C’de 30 dakika karıştırmayı takiben yağ filtre edilerek, aletsel renk, yağ kaybı, serbest yağ asitliği (SYA), asit sayısı ve peroksit sayısı (PS) tespit edilmiştir. Beta karoten rengi için kontrole göre toplam renk farkı (E) en yüksek örnekler 2.3, 2.1 ve 1.8 değerleriyle T.A.T.-1, T.A.T.-2 ve halloysit ile muamele edilmiş örneklerde ölçülmüştür. Bu grup örneklerde ağırlık kaybı en az %22.1 ile bentonit ve en fazla %45.3 ile perlit muamelelerinde görülmüştür. Ayrıca serbest yağ asitliğini en fazla düşüren (%7.7) Magnesol XL kili olmuştur. Benzer şekilde T.A.T.-1 ve sepiyolit ile muamele edilmiş örneklerde PS değeri sıfır iken kaolin ile muamelede 79.1 meqO2/kg yağ olarak ölçülmüştür. Bu grupta sepiyolit ve Magnesol XL en başarılı sonuçları sağlamıştır. Klorofil katılan örneklerde yeşil renk en başarılı olarak sepiyolit tarafından (E=6.2) uzaklaştırılmıştır. Bu grup örneklerde ağırlık kaybı en fazla perlit (%52.9), en az bentonit (%23.5) ile muamele edilmiş örneklerde ölçülmüştür. SYA en fazla Magnesol XL (%5.9), ve PS en fazla T.A.T.-2 ve zeolit (0 meqO2/kg yağ) tarafından azaltılmış olup bentonit ve Magnesol XL örnekleri bu grupta öne çıkmıştır. Daha önce bu amaçla çalışılmamış olan halloysit ile genelde iyi sonuçlar sağlamıştır. Tüm killer için asit aktivasyonu, boyut küçültme, nano boyutta kil olarak hazırlama ve sonikasyon gibi modifikasyon teknikleri önerilmiştir.
Bakteriyosinler: Sınıflandırılmaları, Etki Mekanizmaları ve Gıda Muhafazasında Kullanımları
Authors: MEHENKTAŞ Cesur
Published: July 2022

Bakteriyosinler çeşitli bakteri türleri tarafından üretilen ve diğer mikroorganizmalar üzerinde inhibe edici veya öldürücü etki gösteren peptitlerdir. Sahip oldukları bu etkiler nedeniyle, bakteriyosinler gıda muhafazasında da kullanılmaktadır. Bu derlemede, bakteriyosin üreten bakteri türleri, bakteriyosinlerin sınıflandırılması, etki mekanizmaları, laktik asit bakterilerinin ürettiği bakteriyosinler ve bakteriyosinlerin gıda muhafazasında kullanımı konuları ele alınmıştır.
A legal review of sieges in modern war
Authors: Fox Amos C. , Watkins Beau
Published: July 2022

This paper examines the relationship between Western military doctrine, international law, and the impact of sieges in war. This paper examines three case studies – the battles of Mosul (2016–2017), the Second Battle of Donetsk Airport (2014–2015), and Ghouta – to analyze the effect of international law on the conduct of sieges and how that impacts the attacker, the besieged, and the innocent bystanders. In the end, we find that Western military doctrine is inadequate to address siege situations, which in turn can result in mishandling siege situations from an international law standpoint. Additionally, we find that international law, as well as applied law, provides the actors therein sufficient leeway to create the conditions for the siege to continue to be used well into the future.
Molecular docking analysis on 16 therapeutic ligands of Ocimum tenuiflorum L. (Tulasi) and their prospects in drug design for COVID-19
Authors: Anantharam Guruprasad , Geetha S. , Santhana Pandi P. , Krithika N. , Chittibabu C. V.
Published: July 2022

The PyRx software and Discovery studio were used in the present molecular docking studies of the 16 ligands of Ocimum tenuiflorum L., selected based on their high therapeutic potentials, viz., (E)-6-hydroxy-4,6-dimethylhept-3-en-2-one, Apigenin, Bieugenol, Cirsilineol, Cirsimaritin, β-Caryophyllene epoxide, Dehydrodieugenol B, Eugenol, Ferulaldehyde, Isothymonin, Isothymusin, Linalool, Luteolin, Ocimarin, Rosmarinic acid, and Thymol. Saquinavir was used as a positive control. The binding affinities of the 16 ligands to the main proteases of COVID-19 6LU7 and 6Y2E (critical for viral replication) and their ability to arrest the virus replication were recorded. The binding affinities of the ligands to 6LU7 and 6Y2E ranged from -4.3 and -4.7 kcal/mol (for (E)-6-hydroxy-4,6-dimethylhept-3-en-2-one) to -7.6 (for Rosmarinic acid to both target proteins). While the corresponding values for the control drug Saquinavir were -7.8 and -7.6 respectively. The Rosmarinic acid, in binding with both the proteases (-7.6 and -7.6 kcal/mol) showed six conventional hydrogen bonds, one carbon hydrogen bond (ASP 153 had one conventional hydrogen bond and one carbon hydrogen bond), one Pi-alkyl bond, one Pi-Pi stacked bond, eight van der waals bonds for 6LU7 protease; it formed three conventional hydrogen bonds, two Pi-alkyl bonds, one unfavourable donor – donor bond and 14 van der waals bonds with 6Y2E protease. The control drug – Saquinavir in binding with 6LU7 protease showed 12 van der waals, one alkyl, one Pi-alkyl, one Pi-cation, one Pi-stacked and four conventional hydrogen bonds, which indicates that it has less affinity when compared with Rosmarinic acid. Similarly, the control drug on binding with 6Y2E protease exhibited ten van der waals, four Pi-alkyl, one cation and three hydrogen bonds. The results are in conformity to similar other studies, and herald a promising scope for Rosmarinic acid as lead molecule in the drug discovery for COVID-19.
Producción de alevinos de trucha dorada (Oncorhynchus aguabonita) bajo control de temperatura en la etapa de eclosión de ovas embrionadas en la estación acuícola terranova
Authors: Oliva Mario , Avis Royler , Mori Roberto , Yuji Ricardo , Fernández Víctor
Published: July 2022

El estudio se desarrolló en las instalaciones de la Estación Acuícola Terranova en el distrito de Molinopampa, Amazonas, lo cual estuvo comprendido en el periodo entre agosto y octubre del 2021 teniendo como objetivo determinar los índices de eficiencia productiva de alevinos de trucha dorada (Oncorhynchus aguabonita) bajo control de temperatura en la etapa de eclosión de ovas embrionadas. Se trabajó con 4950 ovas embrionadas procedentes de la región Puno, que fueron distribuidas en tres tratamientos basados en nivel de temperatura del agua en la etapa de eclisión (T1: 8°C, T2: 11°C y T3: 14°C). Los resultados al finalizar la investigación indicaron a T2 como el tratamiento de mejor respuesta en cuanto a tasa de mortalidad (2,85%) y eficiencia de eclosión de ovas embrionadas (97,15%); igualmente ocurrió en las fases larvaria y alevinaje con mejores resultados de T2 con mortalidad de 6,36% y sobrevivencia de 93,64% en fase alevinaje. En cuanto a los resultados sobre crecimiento de alevinos al término del estudio se encontró como mejor tratamiento a T2 con 5,65 cm longitud y 3,50 g peso; asimismo el tratamiento T2 resaltó en ganancia de peso (1,75 g) y factor de conversión alimenticia con 0,75 en promedio.
Investigating the educational environment of the veterinary college at Islamic Azad University Shahrekord Branch from a veterinary student's perspective
Authors: Kosari Neda , Niknampour Fatemeh
Published: July 2022

Objectives:

The quality of the educational environment is among the most important quality indicators of higher education. Therefore, this study aimed to improve the quality of the educational environment based on the Dundee Ready Educational Environmental Measures model from veterinary students’ perspective at the Faculty of Veterinary Medicine, the Islamic Azad University of Shahrekord Branch in 2019.

Material and Methods:

A questionnaire was given to 297 students at an average age of 23 + 3 years. The data collection tool of this cross-sectional study was a 50-point questionnaire. The obtained data were assessed using descriptive statistical indicators, including mean, standard deviation, independent t-test, independent t-test, and one-way analysis of variance. Afterward, various questionnaire dimensions were evaluated based on gender variables, study locations, grade averages, and semesters.

Results:

The results revealed a statistically significant difference between male and female students regarding their perception of professors (P = 0.017), such that the average score in female students was higher than male students (32 vs. 29.21).

Conclusion:

Overall, girls’ satisfaction in this dimension was more than boys. In addition, the results showed that the perception score of social conditions in students above semester 8 was significantly lower compared to those lower than semester 8 (20.22 vs.24.65) (P < 0.001).
Gaya Belajar dan Kreatifitas Mahasiswa Program Studi Manajemen Pendidikan Islam
Authors: M. Arif  , Hayati Najmi , Afrinaldi  , Saputri Siti , Ridwan
Published: July 2022

Dewasa ini gaya belajar dapat menjadi permasalahan urgent pada setiap mahasiswa maka sangat diperlukan kreatifitas dalam meningkatkan minat belajar agar meningkat pula sistem pendidikan di Indonesia. Dalam penelitian ini peneliti menawarkan desain penelitian menggunakan pendekatan kuantitatif menggunakan metode survei. Penelitian yang dilakukan di IAIN Bukittinggi ini melibatkan 44 mahasiswa dengan instrumen penelitian yaitu mengumpulkan data berupa angket dengan skala likert. Penelitian dianalisis menggunakan statistik deskriptif dan inferensial. Statistik deskriptif terdiri dari nilai min, standar deviasi, persentase dan frekuensi. Sedangkan statistik inferensial melibatkan penggunaan teknik statistik MANOVA dan Korelasi Pearson. Adapun hasil dari penelitian ini ialah tingkat gaya belajar kompetitif, menghindar dan bebas berada pada level tinggi, sedangkan gaya belajar kolaboratif berada pada level rendah. Serta kreatifitas keaslian, kelenturan dan kelancaran mahasiswa berada pada tahap yang dominan atau tinggi. Tes MANOVA menunjukkan tidak ada perbedaan yang signifikan jenis gaya belajar dan kreatifitas mahasiswa berdasarkan gender. Namu pada analisis korelasi Pearson menunjukkan bahwa ada hubungan yang signifikan antara gaya belajar dan kreatifitas mahasiswa. Penelitian seperti ini diharapkan dapat dilakukan dari waktu ke waktu sesuai dengan kebutuhan guna mengetahui perubahan gaya belajar dan kreativitas mahasiswa seperti dapat mengaitkan dengan variabel lain di antaranya gaya belajar, strategi belajar dan prestasi akademik, karakteristik kepribadian dan prestasi akademik,. Ketiga variabel tersebut tidak dibahas dalam penelitian ini. Padahal, akan sangat bermanfaat bagi mahasiswa jika ketiga variabel ini dipelajari dan diidentifikasi penyebabnya
Evaluation of the novel Blue Emitting Phosphor with High Thermal Stability and High Color Purity for Solid State Lighting Applications - Ca2MgSi2O7: Eu2 +
Authors: Shukla Dipti
Published: July 2022

This study deals with the new blue release LED phosphor activated by Eu2+. The luminescence properties of blue-emitting phosphor di-Calcium magnesium di-Silicate (Ca2MgSi2O7) doped with europium Eu2+are extensively investigated. This phosphor is produced by the high-temperature solid-state reaction method. The phase structure and crystalline size, surface morphology and elemental analysis were investigated by X-ray diffraction technique (XRD), Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray spectroscopy (EDX). The optical properties are investigated by photoluminescence (PL) properties. Phase structure of Ca2MgSi2O7: Eu2 + is a carbonite-type structure belonging to tetragonal crystallography with the space group P4̅21m; this structure forms a member and layered compound in the Myelite group. The surface of the prepared phosphors is not detected uniformly and the particle distribution is within the nanometer range. EDX ensures components of Eu2 + doped Ca2MgSi2O7 phosphor. Under UV induction, the main emission peak appeared at 470 nm. This emission peak is attributed to the typical emission of Eu2+ due to the 4F9/2 → 6H15/2 transition. The blue light-emitting properties and excellent light response of these silicate phosphors make them suitable for photonic applications and open new avenues for solid-state lighting, cathode ray tubes, fluorescent lamps and scintillators etc. The phosphor system has been researched as a new candidate for phosphor-converted white light-emitting diode (LED) applications.
Activity of Aegle marmelos (L) Correa (Buah Maja) Ethanol Extract to Multiresistant Eshecichia coli Clinical Isolates from Urinart Tract Infection Patients
Authors: Rostinawati Tina , Saputri Wahyu Eka , Wicaksono Imam Adi , Subarnas Anas
Published: July 2022

The increase in resistance of Escherichia coli bacteria that caused urinary tract infections to antibiotics narrows the selection of effective treatment which encourages the development of treatment therapies using natural ingredients. Maja fruit [Aegle marmelos (L.) Correa] is a plant that has shown antibactericidal activity against gram-negative bacteria, one of which is Escherichia coli. This study aimed to determine the antibacterial activity of fruit Maja extract, minimum inhibition concentration (MIC) and the minimum bactericidal concentration (MBC) of fruit Maja extract and the comparative value of gentamycin against Escherichia coli resistance isolated from urinary tract infection patients. The methods are extraction of Maja fruit by using 96% ethanol, agar diffusion method with paper disc and determination of MIC and MBC using microdilution method. The results showed that the ethanol extract of Maja fruit had antibacterial activity with value of MIC50 as 1400-1500 μg/ml, the value of MIC90 was 1600 μg/ml and the value of MBC was in the range concentration of 1700-2000 μg/ml against E. coli isolate I. Against E. coli isolates II, value of MIC50 was in concentration of 2900 μg/ml, MIC90 was in concentration 3000 μg/ml and the value of the MBC is in range 3150-3500 μg/ml. The comparative values of the antibacterial activity of gentamycin on fruit maja extract are 1:5.871 x 103.
Adsorption of chromium (VI) ions from aqueous solution on activated carbon prepared from Centella asiatica leaves
Authors: Nirmala S. , Kumaraguru N.
Published: July 2022

The adsorption ability of activated carbon derived from Centella asiatica leaves to eliminate Cr (VI) ions is explored in this research. The batch mode method has been used to examine the adsorption process as a function of pH (2 to 10), contact time (10 to 90 min), adsorbent dose (25 to 150 mg/g), temperature (30 to 60oC) and initial concentration (10 to 50 mg/L). The isotherms (Langmuir and Freundlich) and kinetic models (pseudo-first-order and pseudo-second-order) were used to test the adsorption data. The obtained findings suggest that the highest percentage of Cr (VI) ions removal (80%) was achieved at contact time (90 min), pH 6, adsorbent dose (100 mg/g), initial concentration (10 mg/L) and temperature (300C). The Langmuir isotherm equation showed better fit. The rate of adsorption was found to confirm pseudo-second-order kinetic model.
Investigation of Ambient Air and its Quality around University Campus and National Highway (NH-92) at Etawah Road, Gwalior, India
Authors: Singh G.K. , Rai S. , Jadon N.
Published: July 2022

A continuous study of ambient air quality is necessary for determining a regional environmental condition, mainly air pollutants. Pollutant concentrations, sources and weather conditions all have an impact on the quality of the air we breathe. The current study attempted to investigate the air quality in Gwalior city by using two separate locations. In urban areas, the contribution from automobile sources has the most significant impact on air quality. High levels of air pollution have a variety of harmful health consequences. The air quality inside/outside of the university campus is evaluated in this study. Air pollution has serious health consequences for humans, animals and plants. It is difficult to predict the health effects of low-level exposure. The World Health Organization has specified the various criteria gases that affect human health and crops. Different pollutants, mainly Particulate Matters, i.e. PM10, PM2.5, SOx, NOx and SPM, are investigated and their concentration is also estimated for comparative study.
Phytochemical evaluation and Chemical characterization of Bauhinia variegata L. bark extract by TGA/ DSC, FT-IR and GC-MS analytical techniques: Pharmaceutical Aspects
Authors: Khanna Tanvi , Dave Akash , Robin Pushpa
Published: July 2022

Bauhinia variegata (Linn.), Caesalpiniaceae, known as Kachnar in Ayurvedic texts has been shown to have promising anticancer potential. The presence of bioactive molecules in plants which can be commercialized has led to research in knowing their chemical properties. Previous studies from our laboratory have validated the claim of anticancer property of Bauhinia variegata by providing biochemical evidence for the effect of petroleum ether bark extract (PEBE) and chloroform bark extract (CBE) on A549 and H460 lung cancer cell lines respectively. This work aimed at the application of various analytical techniques (thermal analysis, Fourier infrared transform spectroscopy and GC-MS) in the characterization of dried extracts of Bauhinia variegata with medicinal properties. TG-DSC-FTIR-GC-MS was applied to monitor the thermal stability and chemical properties of Bauhinia variegata bark extracts. The TG analysis of PEBE and CBE showed mass loss within three steps in different temperature ranges. The DSC curves for the dried extracts of Bauhinia variegata showed that thermal processes occur between 50 – 100°C for PEBE and 50-70°C for CBE. The FTIR spectroscopic studies of petroleum ether and chloroform bark extracts of Bauhinia variegata revealed different characteristic peak values with various functional groups in the extracts. The GC-MS study of PEBE revealed 18 compounds and CBE revealed 8 compounds. Thus, we have been successful in narrowing down to very few probable anticancer compounds from Bauhinia variegata bark extracts and also through this study, it was possible to substantiate the possibility of applying these techniques for use in the herbal medicines production from medicinal plants.
In vitro Evaluation (Antioxidant Activity) of coumarin derivatives
Authors: Devi Sarika , Singh Pooja , Rathi Vaibhav , Kumar Praveen
Published: July 2022

Coumarin is a heterocyclic molecule associated with beneficial human health effects such as to reduce the risk of cancer, diabetes, cardiovascular and brain disease. These effects are thought to be related to free radical scavenging due to their antioxidant properties. Coumarin is a substance that has been synthesized in many of its derivatives in recent years. This entity is a major source of interest for many medicinal chemists to explore its various pharmacological possibilities, especially anticoagulant activity. The antioxidant activities of two synthesized coumarin derivatives namely 2-(4-methyl-2-oxo-2H-chromen-7-yloxy)-N'-(1-(4-aminophenyl)ethylidene) acetohydra zide [M1] and 2-(4-methyl-2-oxo-2H-chromen-7-yloxy)-N'-(1-(2 hydroxy phenyl) ethylidene) acetohydrazide [M2] were studied with the DPPH method. Structure of two coumarin synthesized compounds is proposed on the basis of spectroscopic evidence.
Occurrence, Distribution, Conservation, Ethanobotanical and Pharmacological aspects of endangered medicinal herb belonging to Genus Rheum
Authors: Upadhyay Sweta , Uniyal Anjali , Kumar Vijay , Gupta Sanjay
Published: July 2022

Rheum is normally known by the name Indian rhubarb, an endangered species of Northern Himalaya and belongs to Polygonaceae family. It is stout perennial herb distributed through the northern Himalayas at a height of 2800 to 3600 M. Rhubarb is efficiently used in Unani, Ayurvedic and Chinese medicine system. Rhubarb is known to be a common ingredient in almost all Ayurvedic medicines related to gastrointestinal diseases. The common phytoconstituents of this species are derivatives of hydroxyanthraquinone like Emodin, Rhein, Aloe-emodin etc. Brief review of literature shows that the component Emodin has the anticancerous property and a great potential to inhibit cell proliferation. Rheum also has antimicrobial, antifungal and antibacterial activity. Along with medicinal uses, this herb is used in cosmetics, dyes and as food colouring agent. Rheum is highly diverse in its genetic constitutes. According to IUCN, this species is rapidly declining in its natural habitat. Thus the regeneration through tissue culture holds a major place for conservation; explants used for regeneration can be shoot tip or excised leaf. The only study about its genetic diversity and population structure in India is in Jammu and Kashmir which shows the way for study in other States also.
בין הגליל ליהודה: להתהוותה של הגיאוגרפיה הנוצרית הקדושה בשומרון
Authors: Schwartz Amichai
Published: July 2022

This article deals with the creation of a Christian "holy geography" in Samaria. Byzantine authorities and Church clergy, among others, embarked upon a long and complex process through which they attempted to Christianize the entire region of Samaria. This included gaining control of holy sites and exerting pressure on the Samaritan population to convert to Christianity. This article demonstrates that most Christian attention was devoted to the Samarian cities of Neapolis and Sebastia. The holy sites in Nablus were related to biblical figures such as Jacob and Joseph, who were viewed as prefiguring Jesus. The central holy site in Sebastia was related to the figure of John the Baptist and, to a lesser extent, other biblical figures such as Obadiah and Elisha. These attempts at Christianization were not successful in the Samarian countryside, and an enduring Christian presence was limited to the urban holy places.
תחושת סיכון ומוגנות מנקודת מבטם של ילדים המתגוררים באזור של מתיחות ביטחונית
Authors: Shilo Yaara
Published: July 2022

The current study deals with perspectives regarding risk and protection factors among children living in the Benjamin region, which is characterized by recurrent security threats and terrorist incidents. Previous studies have addressed the perceptions held by adults and parents regarding risk and protection factors, but none have examined children's perceptions. The aim of the study was to examine the effects of living in high-risk areas on children, and their perceptions regarding risk factors and protection factors. The study was conducted among 31 boys and girls in preschool, aged four to six, living in the Benjamin region. It utilized a qualitative method and a combination of Photovoice and drawing tools. The data revealed 16 categories. Eight categories refer to risk factors, nine categories relate to protective factors, and one category, "home and place in a religious and geographical context," relates to both. "relationships" is a unique and particularly interesting theme in children's perception of protective factors. Two categories, "home and place in a religious and geographical context" and "relationships," demonstrate the uniqueness and complexity of the perception of risk factors and protective factors among children living in an area of security-related tension. This emphasizes the importance of parents and kindergarten teachers as a protective factor for children. Further, it accentuates the need for training in risk and protection. The article highlights the importance of hearing children's voices and their participation in decision-making processes related to them.