bluuebunny/crossref_metadata_2025 huggingface dataset:
Race, Stress, and Breast Cancer: A Scoping Review
Authors: Eltoum Noon , Alamin Faris , Hildreth Keyonsis , Abdelrahim Sara , Aneja Ritu , reeder-hayes katherine , Rosenberg Abby , Kaiser Kathryn , Rocque Gabrielle
Published: October 2024

Objective Toxic stress may influence breast cancer (BC) risk and progression through various physiological and biological pathways, potentially differing based on racial categories. We systematically reviewed the literature on the relationship between race, stress, and BC.Methods We searched PubMed (prior to August 2023), Embase, Web of Science, PsycINFO, and Scopus (prior November 2023) to identify relevant peer-reviewed studies. Two independent reviewers screened titles, abstracts, and full text, with disagreements resolved by discussion or a third reviewer. Data extraction and thematic synthesis were conducted independently.Results We identified 30 articles, including 21 original observational studies and 9 reviews. Primary studies explored biological markers including measures of allostatic load (AL), epigenetic changes, and social determinants of health. Studies explored biological marker, AL, epigenetic changes, and social determinants of health. Black women with BC exhibited higher AL and shorter telomeres compared to White women. Epigenetic modifications were associated with social determinants, potentially influencing BC risk and aggressiveness. Significant associations were found between neighborhood disadvantage, social support, and psychosocial stress among women of color with BC.Conclusion This review provides a landscape view of the current evidence on the complex interplay between social stressors, biological responses, and racial and ethnic disparities in BC outcomes. Findings highlight the significant role of chronic psychosocial stress in the disproportionate burden of breast cancer faced by marginalized groups. Further research is needed to explore mechanisms and evaluate multilevel interventions addressing individual stress management, neighborhood resources, and societal-level policies to improve breast cancer prevention, detection, and management.
Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in Anopheles mosquitos while reducing their lifespan and malaria parasite burden
Authors: Camacho Emma , Dong Yuemei , Chrissian Christine , Cordero Radamés , Saraiva Raúl , Anglero-Rodriguez Yessenia , Smith Daniel , Jacobs Ella , Hartshorn Isabelle , Patiño-Medina Jose , DePasquale Michael , Dziedzic Amanda , Jedlicka Anne , Smith Barbara , Mlambo Godfree , Tripathi Abhai , Broderick Nichole , Stark Ruth , Dimopoulos George , Casadevall Arturo
Published: October 2024

L-3,4-dihydroxyphenylalanine (L-DOPA), a naturally occurring tyrosine derivative, is prevalent in environments that include mosquito habitats, potentially serving as part of their diet. Given its role as a precursor for melanin synthesis we investigated the effect of dietary L-DOPA on mosquito physiology and immunity to Plasmodium falciparum and Cryptococcus neoformans infection. Dietary L-DOPA was incorporated into mosquito melanin via a non-canonical pathway and had profound transcriptional effects that were associated with enhanced immunity, increased pigmentation, and reduced lifespan. Increased melanization resulted in an enhanced capacity to absorb electromagnetic radiation that affected mosquito temperatures. Bacteria in the mosquito microbiome were sources of dopamine, which is a substrate for melanization. Our results illustrate how an environmentally abundant amino acid analogue can affect mosquito physiology and suggest its potential usefulness as an environmentally friendly vector control agent to reduce malaria transmission, warranting further research and field studies.
Prevalence of Disorder of Villous Maturation and the Pattern of CD15 Immunohistochemical Expression in Placentas with Late Intrauterine Fetal Death
Authors: saba Sayedatus , Begum Shahnaj , Ferdous Jesmin Naz , Billah Md. Mustain
Published: October 2024

Background
Disorder of villous maturation is one of the main reasons for antenatal hypoxia and fetal deaths. Meticulous microscopic and CD15 immunohistochemical studies of such cases may provide valuable information regarding the cause of intrauterine fetal deaths (IUFDs), can help to avoid diagnostic dilemmas and can offer potential treatment options for its prevention in future pregnancies.
Objective
To determine the types of disorders associated with villous maturation in the placenta in late intrauterine fetal death patients, identify delayed villous maturation via histopathological and CD15 immunohistochemical studies and determine its association with recurrent pregnancy loss.
Method
A cross-sectional study was carried out in the Department of Pathology, Sir Salimullah Medical College Mitford Hospital, Dhaka, from March 2021 to January 2023. A total of 80 patients with late IUFDs were included in this study. The placentas of the dead newborns were histopathologically analyzed, and CD15 immunohistochemistry was performed.
Result
Among the 80 patients, 40 (50.0%) were multiparas, 36 (45.0%) were primis, and only 4 (5.0%) were grand multipara patients. Twenty (25.0%) patients had a history of one IUFD, and 4 (5.0%) patients had a history of multiple IUFDs. Twenty-eight (35%) patients had disorders of villous maturation, among whom 19 (23.8%) had delayed villous maturation (DVM), 4 (5.0%) had malformed villi, 3 (3.8%) had distal villous hypoplasia, 1 (1.3%) had deficiency of intermediate villi and 1 (1.3%) had accelerated villous maturation. CD15 immunostaining was performed in 53 patients, including villitis of unknown origin, disorders of villous maturation and villous edema. Among them, 34 (64.15%) had negative CD15 expression, whereas 19 (35.8%) had positive CD15 expression. All 19 patients with delayed villous maturation had positive CD15 expression (100%), which confirmed their histological diagnosis and ensured the complete exclusion of other false positive cases. Among them, 8 (42.1%) had moderate CD15 expression, and 11 (57.89%) had severe CD15 expression. Among the 13 multipara patients with DVM, 12 (92.3%) had a history of previous IUFD. Among the remaining 31 multipara patients with no DVM, 11 (35.5%) had a previous history of IUFD. A significant difference in history of previous intrauterine fetal death was observed between the DVM present and absent groups (p = 0.001).
Conclusion
This study revealed that disorders of villous maturation are among the main causes of late IUFD and that DVM shows a distinctive pattern of CD15 immunohistochemical expression. Moreover, this study shed light on the association between DVM and recurrent pregnancy loss. The identification of DVM can guide physicians in decision making regarding the management of the patients and prevention of further pregnancy losses.
Particle Design via Powder Synthesis: Production and Characterization of a Mixed Oxide Catalyst for Alkaline Water Electrolysis
Authors: Buchheim Johannes Rolf , Drescher Viktor , Vockenberg Thorben
Published: October 2024

The Glatt Powder Synthesis offers a versatile tool for the development and industrial manufacturing of innovative materials for catalyst production. This technology is exemplified by the material Ba0.5Sr0.5Co0.8Fe0.2O3−δ (BSCF), showcasing its application as a catalyst for the Hydrogen Evolution Reaction (HER). The effectiveness of this method is attributed to the specific conditions present in the pulsating hot gas flow.
Our Approach to Reduce the Risk in Cesarean Section Patients with High Infection Risk
Authors: Kurkut Bülent , Yıldırım Mem Arjen , Doğan Zeki , Akbaş Hümeyra , Kavak Salih Burçin
Published: October 2024

OBJECTIVE
Cesarean section operations are seen as the most intensively performed surgical procedure worldwide. Although there are many approaches to reduce surgical complications, there are no methods that prevent complications 100%. Surgical site infection (SSI) is also not a preventable complication. Therefore, studies are ongoing to reduce the morbidity and mortality risks arising from SSI. We aimed to report our approach to prevent or reduce SSI in patients undergoing cesarean section with high infection risk and present the results.
MATERIALS METHOD
This retrospective cohort study was conducted between May 2017 and June 2024. A total of 200 patients with high risk of surgical site infection after cesarean section in a secondary care hospital were included in the study. The patients were divided into 4 groups according to their risks. These four patient groups were subjected to certain steps.
RESULTS
Among 200 high-risk patients who underwent cesarean section during the study period, SSI developed in a total of 6 (3%) patients, including 2 deep and 4 superficial infections. Of the 2 patients with deep infection, 1 was morbidly obese and the other was in the group of 30 patients with pregestational DM and premature rupture of membranes (PROM) occurring between gestational weeks 34-37, who
underwent cesarean section due to non-initiation of labor or unsuccessful induction. PRM is considered the highest risk factor for deep SSI (6.6%). SSI did not develop in any chorioamnionitis case. Six patients who developed SSI received medical treatment. No secondary operation or secondary suture was needed.
CONCLUSION
We found that our approach was effective in preventing or reducing the infection risk in cases with a high infection risk (PROM, cervical patency, frequent vaginal examination during labor, chorioamnionitis) in which the vagina-cervix barrier was eliminated when an indication for cesarean section occurred.
However, further studies with larger samples are needed.
A goal programming approach based on score function of the pythagorean fuzzy sets
Authors: Seal Somen , Ray Partha , Deb Sayan Chandra , Dey Agniva
Published: October 2024

Goal programming is a particular branch of operation research that is used to solve many problems where multiple goals or objectives are to be taken into account. In order to increase the efficacy of the conventional intuitionistic goal programming method, a new approach is presented in this paper, where a score function of the pythagorean fuzzy sets has been introduced. This paper presents the proof of convergence criterion for this new method, as well as a theorem illustrating the failure of the conventional intuitionistic goal programming method to optimize several problems. Lastly, to demonstrate the proposed method, a case study of a supply chain management problem using the multi-criteria decision-making (MCDM) approach has been taken. The outcomes of the case study show that the proposed technique outperforms the conventional intuitionistic goal programming method in terms of efficacy.
Targeting the Galectin-1/Ras Interaction for Treating Malignant Peripheral Nerve Sheath Tumors
Authors: Wang Hsiao-Chi , Torres Keila , Xia Roger , Malogolowkin Marcio , Hsu Ssu-Wei , Chen Ching-Hsien , Shih Tsung-Chieh
Published: October 2024

Background: Neurofibromatosis type 1 (NF1) is a common inherited neurological disorder that can lead to the development of malignant peripheral nerve sheath tumors (MPNSTs), a highly aggressive form of sarcoma. Current treatment options for MPNSTs are limited, with poor prognosis and high recurrence rates. This study aims to explore the potential of targeting the Galectin-1 (Gal-1) and Ras interaction as a novel therapeutic strategy for MPNSTs.
Methods: Molecular docking simulations were conducted to identify specific residues involved in the Gal-1 and H-Ras(G12V) interaction. LLS30, a compound designed to target the Ras binding pocket on Gal-1, was developed and tested. The efficacy of LLS30 was evaluated through in vitro assays, including cell viability, apoptosis, and co-immunoprecipitation studies, as well as in vivo assays using orthotopic MPNST xenograft and experimental lung metastasis models. Transcriptome sequencing was performed to analyze the impact of LLS30 on gene expression and signaling pathways.
Results: Molecular docking revealed key residues involved in the Gal-1/Ras interaction, and LLS30 was shown to bind to these residues, disrupting the interaction. LLS30 treatment resulted in Ras delocalization from the plasma membrane and suppression of the Ras/Erk signaling pathway. In vitro, LLS30 significantly reduced MPNST cell proliferation and induced apoptosis. In vivo, LLS30 demonstrated potent anti-tumor activity, reducing tumor burden and metastasis while improving survival in animal models. Transcriptome analysis showed that LLS30 downregulates critical pathways, including KRAS signaling and epithelial-mesenchymal transition (EMT).
Conclusions: Interference with the Gal-1/Ras interaction could lead to suppression of the Ras signaling pathway. LLS30 effectively disrupts the Gal-1/Ras interaction, resulting in significant anti-tumor and anti-metastatic effects in MPNST models. These findings indicated that targeting Gal-1 with LLS30 offers a promising therapeutic approach for treating MPNSTs and may also be applicable to other malignancies where Gal-1 and Ras are key oncogenic drivers.
WITHDRAWN: Optimal Distributed Tensor PCA with Statistical Guarantees for Heterogeneous and Decentralized Data
Authors: Li Chris Junchi
Published: October 2024

In this paper, we propose new methodologies for distributed tensor Principal Component Analysis (PCA) in heterogeneous data environments. These environments often arise when tensor datasets are stored across multiple machines, each with unique statistical properties, presenting significant challenges for aggregation and analysis. We extend classical Tucker decomposition to a distributed setting, providing sharp statistical convergence guarantees. Our approach han- dles both homogeneous and heterogeneous tensor data by developing estimators that account for common and individual components, achieving minimax optimal rates in various data settings. Extensive numerical simulations and real data analysis demonstrate the efficacy of our methods, which outperform traditional single-location PCA and pooled estimators, especially in hetero- geneous environments. Key applications include healthcare data analysis and recommendation systems, where privacy and communication costs are critical factors.
Check My Sample Sheet: a Web Application for Validating Illumina Sample Sheets Before Demultiplexing
Authors: Lemée Laure , Ouazahrou Rania , Kornobis Etienne , Cokelaer Thomas
Published: October 2024

The proper configuration of an Illumina sequencing run is paramount to its success, and the sample sheet, which summarizes sample metadata, is a critical component. To ensure accurate demultiplexing and downstream analysis, validation of this sample sheet is essential. Here, we present a user-friendly web application built with Streamlit, leveraging the IEM Python module from the Sequana Python library, designed for thorough sanity checks of Illumina sample sheets.
Our application offers a streamlined solution for sequencing platforms seeking to validate sample sheets prior to initiating demultiplexing processes. Through an intuitive interface, users can easily upload sample sheet files, triggering a suite of validation checks that include crucial parameters such as sample duplication, consistency, and adherence to Illumina formatting standards.
The Web application Check My Sample Sheet empowers users to identify and rectify potential problems preemptively, mitigate errors, and optimize sequencing outcomes. Furthermore, our application's open-source nature facilitates extensibility, allowing for customization to specific workflow requirements or other types of sample sheet formats.
Pseudogap Characteristics in Bi1.6Pb0.4Sr2Ca2Cu3O10+δ Superconductor added with Al2O3–15wt%ZrO2 Nanocomposite
Authors: Aftabi Ali
Published: October 2024

This study, employing the local pair model, examines how the Al2O3–15wt%ZrO2 nanocomposite affects the pseudogap peculiarities and temperature dependence of fluctuation-induced conductivity in the Bi1.6Pb0.4Sr2Ca2Cu3O10+δ superconductor. The fluctuation-induced conductivity survey reveals that the experimental data for both undoped samples and those doped with low concentrations (0.0–1.0 wt%) of the Al2O3–15wt%ZrO2 nanocomposite are well explained by the 3D Aslamazov-Larkin (AL) and 2D Maki-Thompson (MT) models, with 2D fluctuations being the most significant in all samples. The results indicate that samples with 0.1 and 0.2 wt% additives exhibit a wider region of 2D fluctuations than the undoped sample. This suggests that a minor addition of nanocomposite promotes the formation of phase-coherent fluctuating Cooper pairs. The value and temperature variation of the pseudogap Δ*(T) for different composites were deduced using the local pairs model based on experimental fluctuation-induced conductivity data. It was observed that the transition temperature from the Bose-Einstein condensate (BEC) to Bardeen-Cooper-Schrieffer (BCS) regimes of local pairs, Tpair, rose from 117.5 K at the undoped sample to approximately 133.5 K at the composite containing 0.2 wt% additive. However, with higher additive concentrations, Tpair decreased, reaching 120.5 K at the composite containing 1.0 wt% additive. The estimated superconducting gap value at T = 0, Δ(0), rose from 250 K (21.5 meV) for the undoped sample to 254 K (21.9 meV) at the composite including 0.2 wt% additive, then dropped to 243 K (20.9 meV) at the composite including 1.0 wt% additive.
The Minimum Wage Impact on Poverty in Mexico
Authors: Munguia Luis F , Lovera Marco Antonio Gomez
Published: October 2024

This study contributes to the public debate on the effect of the minimum wage on poverty and provides the first estimate specifically for the impact of the minimum wage on multidimensional poverty in Mexico. We find that the elasticity of poverty to the minimum wage is between − 0.36 and − 0.58. This implies that between 2019 and 2022, the number of people in poverty decreased between 23.7% and 37.6% because of the minimum wage. In other words, of the 5.1 million people who escaped poverty, 4.1 million can be attributed exclusively to the minimum wage increase. Additional results indicate that minimum wage increases did not significantly impact the level of employment but did have an impact on labor income. As for social programs, the universal pension shows that a 10% increase in its funding reduces poverty by 13%; a 10% increase in basic education scholarships income contributes to a 3.5% reduction in income poverty.
Analyzing Asymmetric Prosody in Salim's Poetry: A Critical Examination of Words, Phrases, Poetic Lines and Punctuations
Authors: Hamadameen Yadgar Rasool
Published: October 2024

In this research, titled "Analyzing Asymmetric Prosody in Salim's Poetry: A Critical Examination of words, phrases, poetic lines and punctuations," we conduct a comprehensive and practical analysis to identify errors and asymmetric rhythmic prosody within Salim's poetry, focusing on the edition we have diligently worked on. Our study aims to explore potential solutions in accordance with established prosody criteria.
Salim's body of work encompasses several books of poetry, with our research specifically delving into the most recent edition published in 2015 in Sulaimani by Mullah Abdulkarim Mudaris, Fatih Abdulkarim, and Mohammed Mullah Karim. We selected this edition due to its freshness and its incorporation of improvements from previous editions, making it a widely embraced reference among both writers and readers of Salim's poetry.
Our research comprises four primary themes. Firstly, we analyze disruptions at the level of words and phrases. Secondly, we investigate instances of rhythmic disruptions resulting at the level of poetic hemistich. Thirdly, we explore disruptions caused at the level of poetic lines. Lastly, we analyze disruptions at the level of punctuations.
In conclusion, our study offers valuable insights into the content of Salim's poetry by shedding light on its prosodic nuances and providing potential remedies for asymmetries.
The Use of Games as a Vehicle for Foreign Language Teaching and Learning Classroom
Authors: Qani Nasih Najim
Published: October 2024

The study aims to ascertain how games influence students' communication readiness and teachers' perspectives on it as students gave their answer to the questions in the questionnaire. This focuses on using games in the classroom and makes the case that they can be an effective teaching tool. It examines the benefits of using games as a teaching tool and how to get the most out of them for language acquisition. Questionnaires and audio-recorded interviews were used to collect the data. After the survey responses were analyzed, it was discovered that games should be used in foreign language learning classrooms to help EFL learners feel motivated, have fun, and perform well academically while easing the learning process’s boredom and stress.
Factors Associated with Student Feedback to Teachers in Quality Assurance in Iraqi Kurdistan
Authors: Rukhsar Muhammad Omar  , Sarkawt Muhammad Qadir
Published: October 2024

Over the past few decades, the quality of education has emerged as a critical strategic concern in tertiary education institutions worldwide. University managers’ daily tasks now include comparing educational outcomes and rankings, for which quality assurance is significant. Quality assurance incorporates three separate but interdependent elements including student feedback to teachers, teacher portfolios, and continuous academic development. Student feedback concerns the quality and effectiveness of teaching and teacher performance. University instructors often complain about the grades and feedback they gain from students and reckon that the grades are based on students’ rate of success and teachers’ intimacy with students, rather than on teachers’ performances. Therefore, this study is devoted to investigating student feedback and the factors that determine the quality of feedback provided to instructors. To this intent, the study follows the principles of mixed methods in data collection and analysis; using self-reported questionnaires, instructor feedback scores in quality assurance, and student rates of success for each module as well as using IBM SPSS 25 and thematic analysis. The participants include university students and instructors selected from a public university in the Kurdistan Region of Iraq. The study assumes that three factors play a significant role in determining the level of feedback including the rate of success, instructors’ intimacy and rapport with students, and the quantity of material provided to students. The study concludes with far-reaching implications for higher education institutions in the Kurdistan Region of Iraq.
The Use of Illustrators by Bahdini Kurdish Teachers in EFL University Classrooms
Authors: Fakhir Omar Mohammed  , Sazan Abbas Saidgul  , Bokan Ghazi Khalid
Published: October 2024

This study investigates the various kinds of illustrators that male and female Bahdini Kurdish (BK) lecturers perform in EFL university classes. In this area of study, there is still a lack of research on the impact of nonverbal cues on university-level teaching and learning processes when it comes to classroom communication between instructors and students. Ten university instructors, both male and female, were chosen as a sample for the study. Data was gathered from the lecturers using a descriptive observation method based on the illustrator classification system developed by Ekman and Friesen (1969, 1972). According to the results obtained from using excel sheets, the majority of lecturers employed deictic movements in their classes, followed by kinetographs and spatial movements. In terms of gender, females made up a large share of illustrators, except for ideographs.
A Cognitive -Semantic Study of Love Metaphor in Mawlawi Poems
Authors: Karzan Abdullah Jezhny
Published: October 2024

This study is entitled "A Cognitive Semantic Study of Love Metaphor in Mawlawi Poems". It is an attempt to construe the semantic aspects of Mawlawi's poetic texts in light of the cognitive semantic approach. The study, through a linguistic and cognitive analysis, clarifies the way meaning is constructed in the selected poems. It adopts the theoretical framework proposed by the cognitive semantic theory of metaphor. That is, according to the cognitive theory of metaphor, it explores the metaphorization of LOVE in the selected poems. In cognitive approach to metaphor, an abstract concept named the target domain is understood in terms of another called the source domain (usually concrete). The source domain is a conceptual domain used metaphorically so as to understand the abstract target concept, i.e., the target domain is a conceptual domain interpreted through the source domain. The current study investigates the ways in which LOVE as an abstract target concept is construed in terms of other source conceptual domains. That is, the primary aim of the study is to scrutinize how LOVE is metaphorized in the poems, what are the source domains the poet relies upon so as to interpret the target domain of LOVE. In other words, what are the more concrete conceptual source domains that are metaphorically used in order to comprehend the abstract target concept of LOVE?  Accordingly, the recent study is mainly concerned with conceptualization (the way LOVE is conceptualized) which is the cognitive processes of meaning-making. This means that, it illuminates meaning construction process in Mawlawi literature. The study first provides a brief introduction to Cognitive Linguistics and then the nature of meaning in cognitive semantic approach is highlighted. Following this, the cognitive approach to metaphor is presented. The last section is devoted to elucidating the metaphorical structuring of LOVE in Mawlawi's poems based on the contemporary theory of metaphor.
ناسیۆنالیزمی شێعر
Authors: Sharafi Idrees shekh
Published: October 2024

پوختە:
 ناسیۆنالیزمی شێعر تێزێکە سەبارەت بە دەرکەوتنی خود-ئاگایی سیاسی کورد لە مێژووی هزریدا، لە پێناو مانابەخشین بە بوون و شوناس لە چوارچێوەی دەوڵەت/نەتەوەوە بەرەو نیشتمان یان کیانێکی ویژدانی. شاعیرانی پێشەنگی ئەم رەوتە (خانی، حاجی، ئەحمە موختار جاف، قانع و بێکەس) دامەزرێنەری ئاگایی خودیی و پرۆژەی بەسیاسیکردنی زمانن، هەوڵیانداوە دەستکاری ئەو واقیعە بکەن کە وەک حەقیقەت دەرکەوتووە. لە دیدی ئەوان دۆخی سیاسی کورد بەرهەمی گوتاری سیاسی دەسەڵاتی زاڵی "ئەوانیتر"ی سەر کوردستان بووە. لەم سۆنگەیەوە لە میانی پرۆژەی شێعری سیاسی نەتەوەیی و ئاوێتەیەک لە کۆلاژی مێژوو و ئەفسانە و جوگرافیایەکی خەیاڵکرد، بنەڕەتی ئاگایی کوردیان داڕشتووە.  ئەمە ئەگەرچی ئاگایی بووە سەبارەت بە سەردەم و زەمەن و بوونی سیاسییانەی کورد لە مێژوودا، بەڵام هاوکات ئاوێتەی کێشەی فەلسەفەی خودیی subjective philosophy بووە.
   واتە ئیشکالیەتی سەرەکی لە رەوتی رۆنانی نەتەوە، گیرخواردنیەتی لە چوارچێوەی فەلسەفەی ئاگایی بەو جۆری لە فەلسەفەی رەخنەیی  یورگن هابرماس دا تیۆریزەکراوە، کە تێیدا خود دەکەوێتە رامان و راڤەی خۆی و جیهان و بەرەو مۆنۆلۆگ و داخران دەچێت. لە کۆنتێکستی کوردیدا کاتێ ئەمە لە رێگەی زمانی شێعری و تەکنیک و فۆڕمی ئامادە ئەنجام دەدرێت، کێشەکە ئاستێکی باڵاتری ئاڵۆزی بەخۆیەوە دەگرێت و دەشێت بیر لەقاڵب بدات و حوکمی پێشوەختە ناوەرۆکەکەی بجوڵێنێ. بەم جۆرە  پەیوەندی نێوان زمان و ئایدیا و واقیع تووشی شێوان دەکات. بۆ دەرچوون لەم تەنگژەیە، فەلسەفەی نێوانخودێتی دەرچەیەک بۆ پەڕینەوە بەرەو سیاسەتێکی ئەلتەرناتیڤ دەکاتەوە کە ئەرگۆمێنتخوازی و زمانی هاوبەش و دیالۆگ بنەڕەتەکەیەتی بە ئاراستەی کردە و شۆڕش و دەرچوون لە ئەمری واقیع.
   پڕۆژەی ناسیۆنالیزم کە هەمان دروستکردنەی نەتەوە و دەوڵەتە، لە کۆنتێکستی کوردیدا بەهۆی داخرانی بیاڤی نێوانی inter و کامڵنەبوونی پرۆسسی بەسیاسیکردنی هاوبەشەکان و ویستی ئازادی خودەکان، لە جیاتی "بەرەی یەکبوونی نەتەوەیی" کە دوائامانجی بونیاتنانی نەتەوە و دەوڵەتە، بە ئاراستەی حزبی دەسەڵاتگەرا چووە کە کوردی لە رووی شوناس و ئینتماوە زیاتر پارچە پارچە کردوە، ئەمەش وەک واقیعگەرایی لێکداروەتەوە، نەک دەرکەوتنی واقیع لە ئاگاییدا.
وشە سەرەکییەکان: ئاگایی خودی، زمانی شێعری، دەوڵەت/نەتەوە، ناسیۆنالیزم، سیاسەتی نێوانخودی.
زمان و پەیوەندیکردن لای منداڵی ئۆتیزم
Authors: Abdulrahman Shelan Othman
Published: October 2024

پوختە:
   ئەم توێژینەوەیە بە ناونیشانی (زمان و پەیوەندیکردن لای منداڵی ئۆتیزم )ـە، ئامانج لەم توێژینەوەیە ئەوەیە، کە وڵامی ئەم پرسیارانە بداتەوە: ئۆتیزم چیە؟ چ پەیوەندییەکی بە زمانەوە هەیە؟ تایبەتمەندییە زمانییەکانی توشبوی ئۆتیزم چین؟ گرفتی زمانی لە ئۆتیزم گرفتی ئاخاوتنە یا زمان؟ ئەمانە و چەندین پرسیاری تر وەڵامەکانیان لەم توێژینەوەیەدا بەرجەستەن. ئەم توێژینەوە لە دو تەوەر پێکدێت، تەوەری یەکەم تایبەتە بە ناساندنی ئۆتیزم لەم لایەنانەوە: چیەتی ئۆتیزم، چەمک و زاراوە، تایبەتمەندییەکانی، هۆکارەکانی توشبون بە ئۆتیزم.
   تەوەری دوەم: بریتیە لە تایبەتمەندییە زمانییەکانی منداڵی ئۆتیزم، ئەم تەوەرەش ئەم بابەتانە لەخۆدەگرێت: تایبەتمەندییە گوتەییەکانی منداڵی ئۆتیزم، تایبەتمەندییە ناگوتەییەکانی منداڵی ئۆتیزم، هەروەها بە پێی ئەنجامی ڕاپرسیەکە تایبەتمەندەییەکان شیدەکرێنەوە و دەخرێنەڕو،  چونکە ئەم توێژینەوەیە بەشی کارەکی لەخۆدەگرێت، کە فۆڕمی راپرسی دابەشکراوە بەسەر مامۆستایان و ڕاهێنەرانی سەنتەری ئۆتیزم، بڕگەکانی ئەم ڕاپرسیە لە ١٦پرسیار پێکدێت، پرسیارەکان تایبەتن بە لایەنی گوتەیی و ناگوتەیی لە پەیوەندیکردنی منداڵی توشبوی ئۆتیزم. لە کۆتایدا ئەنجام و لیستی سەرچاوەکان و کورتە بەزمانی ئینگلیزی و نمونەیەک لە ڕاپرسییەکە خراوەتەڕو.
ڕۆلی سەربازی یارمحەمەدخانی کرماشانی لە پێشهاتە ناوخۆییەکانی ئێران لەماوەی ساڵانی (1908 - 1912)
Authors: Sadiq Delzar Salih
Published: October 2024

پوختە
 
وڵاتی ئێران لەسەرەتای سەدەی بیستەم کۆمەڵێک پێشهاتی ناوخۆیی گرنگ و هەستیاری بەخۆوەبینی، بەجۆرێک کاریگەری لەسەر سەرجەم کایەکانی ژیانی سیاسی و ئابووری و کۆمەڵایەتی ئەو وڵاتە هەبوو، کە بەقۆناغێکی هەستیاری پڕ لەکێشمەکێشی سیاسی تێپەڕی، لەدیارترین ئەو پێشهاتانەش کە لەئەنجامی خەبات و تێکۆشانی شۆڕشگێڕان و ئازادیخوازان لە ئێران کە لەپێناو هێنانەدی ئازادی سیاسی و ژیانێکی دەستووری هەوڵەکانی خۆیان خستبووەگەڕ هاتە بەرهەم، زۆری نەبرد لەساڵی 1908 بەهۆی ململانێی ناوخۆیی لەنێوان شا و ئازادیخوازەکان سەری کێشا بۆ شەڕی ناوخۆیی و تا ساڵی 1912 درێژەی کێشا. گومانی تێدانییە لەم نێوەندەدا کوردەکانیش لە ڕۆژهەڵاتی کوردستان لەپێناو هاتنەکایەی ئازادی سیاسی و ڕادەربڕین و نەهێشتنی جیاوازی نەتەوەیی و چینایەتی و دابینکردنی یەکسانی و دادپەروەری کۆمەڵایەتی لەپاڵ ئازادیخوازانی ئێرانی خەباتیان کردو ژیانی خۆیان کردە قوربانی، لەدیارترین ئەو کەسایەتیانەش یارمحەمەخانی کرماشانی بوو، کە یەكێک لەدیارترین سەرکردە کوردە ئازادیخوازەکانی وڵاتی ئێران بەگشتی و ڕۆژەهەڵاتی کوردستان بەتایبەتی بوو، ناوبراو لەڕیزی سەرکردە هەرە گەورەو ناودارەکانی مێژووی ئێران دێت، کە لەپێناو ئازادی سیاسی و ڕادەربڕین لەوڵاتی ئێران بەگشتی گیانی خۆی بەخشی.
Isolasi, Skrining dan Identifikasi Fungi Selulolitik Asal Tempat Pengolahan Sampah Terpadu (TPST) Rempoah, Kabupaten Banyumas
Authors: Hikam Arif Rahman , Setio Adinda Eka Murti , Mumpuni Aris , Yulianti Dwiana Muflihah , Dewi Ratna Stia
Published: October 2024

Tempat Pengolahan Sampah Terpadu (TPST) Rempoah, Kabupaten Banyumas memiliki timbunan sampah organik melimpah yang dikomposkan secara alami. Sampah organik dapat terdegradasi secara alami oleh beberapa mikroba, salah satunya adalah fungi selulolitik yang dapat mendegradasi selulosa dengan mekanisme enzimatis. Salah satu upaya untuk mengatasi permasalahan sampah organik yang melimpah adalah mengeksplorasi mikroba yang memiliki potensi dalam menguraikan sampah organik dengan efektif dan cepat. Tujuan dari penelitian ini adalah untuk memperoleh isolat fungi yang memiliki potensi selulolitik asal TPST Rempoah. Penelitian ini terdiri dari tahap pengambilan sampel; isolasi dan pemurnian fungi; skrining fungi selulolitik dengan menggunakan media CMC; dan identifikasi isolat fungi secara morfologi. Hasil penelitian didapatkan 6 isolat fungi selulolitik yang berasal dari Genus Aspergillus yang berhasil diisolasi dari TPST Rempoah. Nilai indeks selulolitik tertinggi dimiliki isolat Aspergillus RB1 dengan nilai IS sebesar 1,33.
Analisis Kualitas Fisika dan Kimia Pada Air Sumur Gali di Kecamatan Kota Atambua Nusa Tenggara Timur
Authors: Blegur Willem Amu , Binsasi Yeremias , Fallo Gergonius , Santos Monika Dos
Published: October 2024

Air merupakan sumber daya penting bagi kehidupan di bumi, termasuk untuk manusia. Salah satusumber penyediaan untuk pemenuhan hidup manusia yaitu sumur gali. Air yang bersumber dari sumur gali perlu memenuhi persyaratan kualitas air agar layak dikonsumsi oleh manusia sehingga tidak menimbulkan sakit. Masyarakat di Kecamatan Kota Atambua, Kabupaten Belu telah lama menggunakan air yang bersumber dari sumur gali. Akan tetapi, pertumbuhan jumlah dan aktivitas masyarakat berpengaruh terhadap kualitas air dari sumur gali. Penelitian ini bertujuan untuk menentukan kualitas air sumur gali di Kecamatan Kota Atambua, Kabupaten Belu, dan menganalisis pengaruh aktivitas masyarakat terhadap kualitas air sumur gali. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan pengambilan sampel air dari sumur gali yang berada di Kecamatan Kota Atambua pada bulan Juni-Desember 2023. Pelaksanaan sampling dilakukan berdasarkan standar sampling untuk mengukur kualitas air dan parameter kualitas air yang diukur meliputi suhu, turbiditas, COD, BOD, pH, total coliform dan fecal coliform. Hasil penelitian menunjukkan bahwa setelah dibandingkan dengan PP Nomor 22 tahun 2021 dan Permenkes Nomor 32 tahun 2017, parameter air sumur gali berupa suhu, pH, CaCO3 dan COD telah sesuai dengan standar baku mutu tersebut. akan tetapi nilai BOD dari air sumur gali yang di Kecamatan Kota Atambua belum memenuhi persyaratan untuk air konsumsi.
HALLEMA: A GOOGLE SITES INTEGRATED ADDIE INSTRUCTIONAL MODEL IN FACILITATING MALAYSIA HALAL CERTIFICATION APPLICATION
Authors:   Academy Contemporary Islamic Studies (ACIS), UniversitiTeknologi MARA (UiTM), Shah Alam, 40450, Malaysia., Payyadhah Borhan Farrah , Syukri Mohd Ashmir Wong Muhammad ,   Academy Contemporary Islamic Studies (ACIS), UniversitiTeknologi MARA (UiTM), Shah Alam, 40450, Malaysia., Hafizah Harun Nur ,   Academy Contemporary Islamic Studies (ACIS), UniversitiTeknologi MARA (UiTM), Shah Alam, 40450, Malaysia., Jaapar Nurzahidah ,   Academy Contemporary Islamic Studies (ACIS), UniversitiTeknologi MARA (UiTM), Shah Alam, 40450, Malaysia., Fitri Mustapa Danial ,   Kolej Profesional MARA Bandar Melaka, Jalan Hang Tuah 75300 Bandaraya Melaka Malacca, Malaysia.
Published: October 2024

The expansion of the halal industry in Malaysia generates a demand for halal-related positions, including halal executive and halal auditor. Higher education institutions in Malaysia that offer halal-related programs are tasked with delivering a halal career-oriented education to cultivate professional graduates prepared for industry employment. Halal graduates should already be familiar with their job scopes, such as applying for the Malaysia Halal certification and developing a Halal Assurance Management System (MHMS) in their workplace. The present studies aim to investigate the integration of the ADDIE model in the development of the Halal Learning Mate (Hallema) using Google Sites and to evaluate the effectiveness of Hallema on the Google Sites platform in addressing project-based learning challenges related to the application of the Malaysia Halal certification.This research was carried out among a class of 23 students from the Bachelor of Halal Industry Management program at UiTM. The data collection instrument consisted of two sets of achievement tests a pre-test set (from the analysis stage) and a post-test set- which were utilized to determine the need analysis for teaching aids based on the students prior knowledge. Next, the evaluation of the effectiveness of Hallema was conducted through descriptive analysis using four variables: information (KN=4.49), accessibility (KA=4.53), information (IN=4.50), and document management (PD=4.60), which were evaluated using a 5-point Likert scale.Results revealed that Hallema is effective as a teaching aid in facilitating Malaysia Halal Certification, with a total mean (of 4.50). Students exhibit more engagement when they perceive the relevance of their learning to real-world applications. Any halal educator may repurpose Hallema for their classroom. This educational resource may facilitate the development of proficient halal practitioners who maintain halal integrity in products and services worldwide.
EFFICACY OF INDUCTION CHEMOTHERAPY WITH PACLITAXEL AND CARBOPLATIN IN LOCALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE HYPOPHARYNX: A DESCRIPTIVE CASE SERIES
Authors: Shahzadi , MBBS , FCPS Kiran , Faheem , MBBS , FCPS , MCPS Mohammad , , PhD Um-e Lela , Zainab , M.Phil. Baneeha
Published: October 2024

Introduction: Head and neck cancer including hypopharyngeal carcinoma is one of commonest malignancies in Pakistan. According to the Pakistan Medical Research Council (PMRC) reports, it was found to be the commonest malignancy in males and was second highest to breast cancer in females. The patients for the management of hypopharyngeal cancer present with locally advanced disease. Induction chemotherapy with paclitaxel and carboplatin is being used for few years but the results have not been documented yet. The aim of this study is to design a protocol in future with improved outcome and acceptable morbidity. Objective:To determine the efficacy of induction chemotherapy with paclitaxel & carboplatin in locally advanced squamous cell carcinoma of hypopharynx in terms of frequency of complete and partial response. Settings:This study was conducted at Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad. Study Design: Descriptive case series. Duration of study: 6 months from 01/08/2017 to 31/01/2018 Material and methods:In this study a total of 59 patients were observed by using World Health Organization sample size calculator where confidence level: 95%, anticipated population proportion: 67%, relative precision: 12%. Moreover, nonprobability consecutive sampling technique was used for sample collection. Results:Mean age was 60 Ã‚Â± 11.87 years. 40(68%) patients were males while 19(32%) were females. 22(38%) patients had carcinoma of stage III, 32(54%) patients had carcinoma of stage IVA while 5(8%) patients had carcinoma of stage IVB. Moreover, induction chemotherapy was effective in 42(72%) patients and was not effective in 17(28%) patients. Conclusion:Our study concludes that induction chemotherapy with paclitaxel & carboplatin was 72% effective in locally advanced squamous cell carcinoma of hypopharynx in terms of frequency of complete and partial response.
An Autoethnography on the Family Relationship Experience and Recovery of an Adult with Childhood Attachment Traumatic Experience
Authors: Ko Se-Won , Kim Myeung-Chan
Published: October 2024

Objectives: The purpose of this study is to explore the impact of childhood attachment trauma experiences in the original family on the experience of family relationships after marriage and the experience of restoring family relationships in the process of post-traumatic recovery from an insider's point of view, to help understand those who have experienced such trauma and to suggest counseling implications. Methods: For this purpose, we applied autoethnography, a qualitative research method, to collect data such as memory data, diary data including self-observation and self-analysis, and family interviews. The collected data were subjected to value coding, emotion coding, and longitudinal coding during data analysis. Results: As a result, it was confirmed that the experience of attachment trauma continues across generations and that maladaptive psychological processes resulting from the traumatic experience are repeated in family relationships after marriage. Moreover, the changing factors that appeared in the process of recovering family relationships were identified. Conclusions: The significance and limitations of this study were presented.
The Spousal Support Effect on Marital Satisfaction in Middle-Aged Couples: Actor-Partner Interdependence Model
Authors: Cho Seong Sook , Kim Minhee
Published: October 2024

Objectives: This study aimed to verify the effect of spousal support on marital satisfaction in middle-aged couples using the Actor-Partner Interdependence Model (APIM). Methods: For this purpose, 223 couples aged 40-60 nationwide participated in the study. Descriptive statistics and correlation analysis were performed using SPSS 23.0, and structural equation modeling analysis was performed using Amos 23.0. Results: The findings of the study are as follows. First, while receiving spousal support had a positive effect on marital satisfaction for both husbands and wives among the middle-aged couples, the partner effect was significant only for wives. Second, giving spousal support had a negative effect on marital satisfaction for wives, and the partner effect was significant for both husbands and wives among the middle-aged couples. Conclusions: In conclusion, the more they perceived receiving spousal support, the higher the marital satisfaction. Also, the more they perceived giving spousal support, the lower their spouses’ marital satisfaction. Implications and limitations of this study were discussed, and suggestions for further studies were recommended.
Tumor-induced inflammation
Authors: MADEJ JANUSZ A.
Published: October 2024

The role of inflammatory cells in the induction of various cancers was presented, with their division into: strong defenders of the body (T CD4+, T CD8+, Th1, Th2, NK, NKT, LAK, CKK, MAIT, T-cell CART), defenders or „collaborators” (B lymphocytes, M1 and M2 macrophages, N1 and N2 neutrophils) and enemies (MDSC, Th17). The described phenomena were correlated with three-stage tumor immunoediting. The range relations between cancer cells (A) and inflammatory cells (B) were presented graphically in the form of mathematical Euler circles in Figure 2, while external factors (A) and internal factors (B) involved in the induction of inflammatory infiltrate, which play an important role in cancer transformation, were illustrated using an adapted Venn diagram (10) in Figure 3. Although some anti-inflammatory drugs (aspirin, COX2) inhibit the risk of colorectal cancer in humans, there is still a long way to go to fully understand how cancer cells „manipulate” inflammatory cells for their growth and survival needs.
Quality of raw cow’s milk intended for processing and retail sale from Eastern Poland
Authors: PYZ-ŁUKASIK RENATA , PASZKIEWICZ WALDEMAR , CHAŁABIS-MAZUREK AGNIESZKA
Published: October 2024

The study assessed the quality of raw cow’s milk intended for processing and retail sale (n = 595 samples and n = 19 production batches, respectively) and the relationship between the number of somatic cell and the fat and protein contents. All milk samples were tested for total bacteria count, somatic cell count, antibiotic residues, and fat and protein contents. Additionally, raw drinking milk samples were tested for counts of Enterobacteriaceae, Escherichia coli, coagulase-positive staphylococci, enterococci, and the presence of Listeria monocytogenes and Salmonella spp. In raw milk samples, TBC, SCC, and fat and protein contents ranged from 4.9 × 103 to 2.3 × 105 CFU mL–1, from 9.9 to 407.8 thou. mL–1, from 3.2% to 5.9% and from 3.0% to 4.8%, respectively, while TBC, SCC, and fat and protein contents in raw drinking milk samples ranged from 1.8 × 106 to 3.3 × 106 CFU mL–1, from 454 to 696.9 thou. mL–1, from 1.67% to 2.88% and from 3.11% to 3.41%, respectively. The mean counts of Enterobacteriaceae, E. coli, coagulase-positive staphylococci, enterococci in raw drinking milk were 4.0 × 105 CFU mL–1, 1.4 × 102 CFU mL–1, 2.4 × 104 CFU mL–1, and 2.2 × 105 CFU mL–1, respectively. L. monocytogenes, Salmonella spp., and antibiotic residues were not detected in any of the samples tested. The study showed that 95% of the raw milk samples were of satisfactory quality, while 100% of the raw drinking milk samples were of unsatisfactory quality in relation to the regulatory thresholds. Additionally, raw drinking milk samples were a vehicle of potentially pathogenic bacteria. The somatic cell count did not affect the fat and protein content in the analysed milk.
The Developing of Pedagogical Competence of Madrasah Ibtidaiyah Teachers Through Formative Assessment Management
Authors: Hikmah Nur , Asikin Ali , Syfa Layinatul , Sabila Aulia Firda
Published: October 2024

Formative assessments play a crucial role in providing valuable feedback to both teachers and students, highlighting progress and pinpointing areas for improvement. This study focuses on the development of teacher competence through the planning, organization, implementation, and supervision of formative assessments at Elementary School. It is a descriptive and qualitative research employing interviews, documentation, and observation methods to gather data, ensuring data validity through triangulation techniques. Data analysis involves collection, presentation, and drawing conclusions. The findings indicate that teachers' pedagogical competence is enhanced through effective formative assessment management, evidenced by thoughtful planning, meticulous organization, and comprehensive execution of formative assessments. Responsibilities for supervision are distributed among Madrasah Heads and Madrasah Supervisors. The study's implications suggest that strengthening teacher supervision in formative assessments can lead to improved pedagogical practices, ultimately enhancing student learning outcomes.
Codification of general principles of administrative law
Authors:   St. Petersburg State University, Vasyilyeva Anna
Published: October 2024

On the basis of the method of historical and comparative legal analysis the experience of codification of the general principles of administrative law of the CIS member states has been studied. The vast majority of codification was carried out by adopting the German model of legislative regulation of administrative procedures. The analysis of reception required the reference to its source — the German model of partial codification of the General Part of Administrative Law. As a result of the study, three models of interaction of the general principles of administrative law and their codification have been identified. The first model is marked by the development of the judicial doctrine of the general principles of administrative law and their subsequent codification. The second model is distinguished by the codification of the general principles of administrative law with the necessity of their subsequent development in the judicial and scientific doctrine. The introduction of the general principles of administrative law by borrowing a foreign codified act due to the resistance of local law, as well as the lack of judicial and scientific doctrine, can create conditions for the emergence in administrative law of a significant gap between “law in books” and “law in action”. In addition, the third model, characterised by the absence of codification of the general principles of administrative law and their differentiated regulation in sectoral laws, has been identified. It has been established that the effectiveness of the general principles of administrative law depends not only (and even not so much) on their legislative consolidation, but on the intensity and quality of judicial activism in the relevant legal system. Moreover, in some legal systems a significant contribution to the identification and development of general principles of administrative law is made by constitutional courts, in other legal systems — by administrative courts.