bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Tirapazamine (TPZ) to Target and Eradicate Hypoxia Tumors by Gold Nanoparticle Carriers
Authors: Ajnai Giimel , Cheng Chun-Chia , Kan Tzu-Chun , Lu Jeng-Wei , Rahayu Sri , Chiu Amy , Chang Jungshan
Published: April 2022

Tumor hypoxia is a hallmark of solid tumors and emerged as the therapeutic target for cancer treatments, such as a prodrug Tirapazamine (TPZ) activated in hypoxia. To increase tumor accumulation, gold nanoparticles (GNPs) were selected to conjugate with TPZ. In this study, we successfully formulated and assessed the biochemical and therapeutic roles of the conjugated gold nanoparticles–Tirapazamine (GNPs–TPZ) on therapeutic assessments of MKN45-induced xenograft animal model. The results indicated that GNPs–TPZ was a potential nanomedicine for selectively targeting hypoxia tumors coupled with decreased side effects on healthy tissue or organs. TPZ significantly reduced cell viability of hypoxic gastric cancer MKN45 cells, but not in cells incubated in normoxia condition. For improving tumor targeting efficiency, furthermore, the GNPs drug carrier was conjugated to TPZ via biding mediator bovine serum albumin (BSA), and we demonstrated that this conjugated GNPs–TPZ retained the unique characteristics of hypoxic toxin and possessed the adequate feature of systemic bio-distributions in animals. GNPs–TPZ nanoparticles revealed their superior affinity to hypoxia tumors in the MKN45 xenograft. Moreover, GNPs–TPZ treatments did not significantly alter the biochemical parameters of blood samples acquired from animals. Taken together, TPZ, a prodrug activated by hypoxia, was conjugated with GNPs, whereas BSA severed as an excellent binding agent for preparing the conjugated GNPs–TPZ nanomedicines. We demonstrated that GNPs–TPZ enhanced tumor targeting, resulting in higher therapeutic efficacy compared to TPZ. We suggest that it may sever as an adjuvant treatment or combined therapy with other chemotherapeutics for the treatment of cancer patients in the future.
Approaching Polymer Dynamics Combining Artificial Neural Networks and Elastically Collective Nonlinear Langevin Equation
Authors: Miccio Luis A. , Borredon Claudia , Casado Ulises , Phan Anh D. , Schwartz Gustavo A.
Published: April 2022

The analysis of structural relaxation dynamics of polymers gives an insight into their mechanical properties, whose characterization is used to qualify a given material for its practical scope. The dynamics are usually expressed in terms of the temperature dependence of the relaxation time, which is only available through time-consuming experimental processes following polymer synthesis. However, it would be advantageous to estimate their dynamics before synthesizing them when designing new materials. In this work, we propose a combined approach of artificial neural networks and the elastically collective nonlinear Langevin equation (ECNLE) to estimate the temperature dependence of the main structural relaxation time of polymers based only on the knowledge of the chemical structure of the corresponding monomer.
Numerical Simulation of Surface Gas Venthole Extraction and the Effect of Ventilation Mode in Pressure-Relief Mining
Authors: Liu Yubo , Zhang Cun , Song Ziyu
Published: April 2022

The stress-relief coal mine methane surface gas venthole is considered an effective method by which to realize coal mine methane exploitation and outburst prevention. Existing stress permeability models for caved zones, fractured zones, and bending subsidence zones were embedded into FLAC3D simulation software by using the FISH language. In cooperation with the in-situ data of a mine in a Huainan coalfield, the permeability distribution of pressure-relief surface gas drainage via different zones was simulated. The results indicated that the surface gas ventholes were effective for gas extraction from mining areas. By analyzing the distribution of permeability, three zones were identified: (1) the fully compacted zone, (2) the gradually compacted zone, and (3) the “O” type fractured zone. The seepage path of pressure-relief surface gas drainage was visualized. Most of the gas seeps into the adjacent rock mass at first and then is extracted through surface gas ventholes. Meanwhile, seepage of gas with different ventilation modes in longwall-panel, U-type, and Y-type was analyzed. Results shows that the Y-type ventilation mode is better than the U-type for gob gas control in the longwall panel. A comparison between the simulated model and the on-site recorded data is conducted, and results show that the model represents the site condition reasonably well. The simulation results provide theoretical guidance to engineering practice.
Investigation of the Mechanical Properties of Inertia-Friction-Welded Joints of TC21 Titanium Alloy
Authors: Li Zihao , Zhao Shengsheng , Li Zhijun , Wang Meng , Wu Fayu , Wang Hongying , Zhou Jun
Published: April 2022

TC21 titanium alloy is a new high damage-tolerant structural material for aerospace applications; its welding performance is very critical for the manufacturing of structural parts. In this research, the inertia friction welding (IFW) process of TC21 alloy was conducted, and the microstructure and mechanical properties of IFW joints were investigated. In tensile tests, specially designed tensile samples with grooves were utilized to achieve the tensile properties of IFW joints. The results show that the microhardness and tensile strength of IFW joints are higher than that of the base metal, but the plasticity of joints is worse compared with the base metal. The SEM results reveal that the weld zone has a dynamic recrystallization microstructure with uniform fine-needle α phases. The microstructure evolution in the weld is the key factor that results in the change of the mechanical properties of TC21 IFW joints.
Synthesis of Novel Luminescent Double-Decker Silsesquioxanes Based on Partially Condensed TetraSilanolPhenyl POSS and Tb3+/Eu3+ Lanthanide Ions
Authors: Marchesi Stefano , Bisio Chiara , Carniato Fabio
Published: April 2022

In this study, novel lanthanide-containing double-decker polyhedral oligomeric silsesquioxanes (POSS) were prepared by combining the partially condensed TetraSilanolPhenyl POSS with terbium (Tb3+) and europium (Eu3+) ions. This open-cage POSS possesses four diametrically opposite silanol groups that are able to coordinate, under mild conditions, different luminescent ions through a simple corner-capping method. The two metal-containing POSS functionalized with Tb3+ and with an equimolar combination of Tb3+ and Eu3+ show a completely condensed structure with different luminescent properties. Their emission features depend on the chemical nature of the metal ions incorporated in the framework. An improved stokes shift was detected in the bimetallic compound containing both the Tb3+ and Eu3+ ions, promoted by the occurrence of a Tb3+→Eu3+ energy transfer mechanism. These characteristics identify this metal-functionalized silica platform as a potential candidate for the development of novel luminescent devices.
A Review of In Vitro Methods for Measuring the Glycemic Index of Single Foods: Understanding the Interaction of Mass Transfer and Reaction Engineering by Dimensional Analysis
Authors: Sun Yongmei , Zhong Chao , Zhou Zelin , Lei Zexin , Langrish Timothy A. G.
Published: April 2022

The Glycemic Index (GI) has been described by an official method ISO (International Organization for Standardization) 26642:2010 for labeling purposes. The development of in vitro methods for GI measurement has faced significant challenges. Mass transfer and reaction engineering theory may assist in providing a quantitative understanding of in vitro starch digestion and glycemic response from an engineering point of view. We suggest that in vitro GI measurements should consider the mouth and the stomach in terms of fluid mechanics, mass transfer, length scale changes, and food-solvent reactions, and might consider a significant role for the intestine as an absorption system for the glucose that is generated before the intestine. Applying mass transfer and reaction engineering theory may be useful to understand quantitative studies of in vitro GI measurements. The relative importance of reactions and mass-transfer has been estimated from literature measurements through estimating the Damköhler numbers (Da), and the values estimated of this dimensionless group (0.04–2.9) suggest that both mass transfer and chemical reaction are important aspects to consider.
Investigation into the Trampoline Dynamic Characteristics and Analysis of Double Bounce Vibrations
Authors: Eager David , Zhou Shilei , Ishac Karlos , Hossain Imam , Richards Adam , Sharwood Lisa N.
Published: April 2022

Double bounce is an unusual and potentially very hazardous phenomenon that most trampoline users may have experienced, yet few would have really understood how and why it occurs. This paper provides an in-depth investigation into the double bounce. Firstly, the static and dynamic characteristics of a recreational trampoline are analysed theoretically and verified through experiments. Then, based on the developed trampoline dynamic model, double bounce simulation is conducted with two medicine balls released with different time delays. Through simulation, the process of double bounce is presented in detail, which comprehensively reveals how energy is transferred between users during double bounce. Furthermore, the effect of release time delay on double bounce is also presented. Finally, we conducted an experiment which produced similar results to the simulation and validated the reliability of the trampoline dynamic model and double bounce theoretical analysis.
Evaluation and Comparison of Ultrasonic and UWB Technology for Indoor Localization in an Industrial Environment
Authors: Crețu-Sîrcu Amalia Lelia , Schiøler Henrik , Cederholm Jens Peter , Sîrcu Ion , Schjørring Allan , Larrad Ignacio Rodriguez , Berardinelli Gilberto , Madsen Ole
Published: April 2022

Evaluations of different technologies and solutions for indoor localization exist but only a few are aimed at the industrial context. In this paper, we compare and analyze two prominent solutions based on Ultra Wide Band Radio (Pozyx) and Ultrasound (GoT), both installed in an industrial manufacturing laboratory. The comparison comprises a static and a dynamic case. The static case evaluates average localization errors over 90 s intervals for 100 ground-truth points at three different heights, corresponding to different relevant objects in an industrial environment: mobile robots, pallets, forklifts and worker helmets. The average error obtained across the laboratory is similar for both systems and is between 0.3 m and 0.6 m, with higher errors for low altitudes. The dynamic case is performed with a mobile robot travelling with an average speed of 0.5 m/s at a height of 0.3 m. In this case, low frequency error components are filtered out to focus the comparison on dynamic errors. Average dynamic errors are within 0.3–0.4 m for Pozyx and within 0.1–0.2 m for GoT. Results show an acceptable accuracy required for tracking people or objects and could serve as a guideline for the least achievable accuracy when applied for mobile robotics in conjunction with other elements of a robotic navigation stack.
A New Approach for Abnormal Human Activities Recognition Based on ConvLSTM Architecture
Authors: Vrskova Roberta , Hudec Robert , Kamencay Patrik , Sykora Peter
Published: April 2022

Recognizing various abnormal human activities from video is very challenging. This problem is also greatly influenced by the lack of datasets containing various abnormal human activities. The available datasets contain various human activities, but only a few of them contain non-standard human behavior such as theft, harassment, etc. There are datasets such as KTH that focus on abnormal activities such as sudden behavioral changes, as well as on various changes in interpersonal interactions. The UCF-crime dataset contains categories such as fighting, abuse, explosions, robberies, etc. However, this dataset is very time consuming. The events in the videos occur in a few seconds. This may affect the overall results of the neural networks that are used to detect the incident. In this article, we create a dataset that deals with abnormal activities, containing categories such as Begging, Drunkenness, Fight, Harassment, Hijack, Knife Hazard, Normal Videos, Pollution, Property Damage, Robbery, and Terrorism. We use the created dataset for the training and testing of the ConvLSTM (convolutional long short-term memory) neural network, which we designed. However, we also test the created dataset using other architectures. We use ConvLSTM architectures and 3D Resnet50, 3D Resnet101, and 3D Resnet152. With the created dataset and the architecture we designed, we obtained an accuracy of classification of 96.19% and a precision of 96.50%.
Grid Frequency Measurement through a PLHR Analysis Obtained from an ELF Magnetometer
Authors: Portillo Francisco , Alcayde Alfredo , García Rosa M. , Novas Nuria , Gázquez José Antonio , Férnadez-Ros Manuel
Published: April 2022

The stability of the power grid’s frequency is crucial for industrial, commercial, and domestic applications. The standard frequency in Europe’s grid is 50 Hz and it must be as stable as possible; therefore, reliable measurement is essential to ensure that the frequency is within the limits defined in the standard EN 50160:2010. In this article, a method has been introduced for the measurement of the grid frequency through a power line harmonics radiation analysis. An extremely low-frequency magnetometer was developed with the specific purpose of monitoring, in real time, the electromagnetic field produced by electrical installations in the range from 0 to 2.2 kHz. Zero-crossing and Fast Fourier transform algorithms were applied to the output signal to calculate the grid frequency as a non-invasive method. As a final step, data for a complete month (May 2021) were compared with a commercial power quality analyzer connected to the main line to validate the results. The zero-crossing algorithm gave the best result on 3 May 2021, with a coefficient of determination (R2) of 0.9801. Therefore, the indirect measurement of the grid frequency obtained through this analysis satisfactorily fits the grid frequency.
Development and Validation of a Digital Image Processing-Based Pill Detection Tool for an Oral Medication Self-Monitoring System
Authors: Holtkötter Jannis , Amaral Rita , Almeida Rute , Jácome Cristina , Cardoso Ricardo , Pereira Ana , Pereira Mariana , Chon Ki H. , Fonseca João Almeida
Published: April 2022

Long-term adherence to medication is of critical importance for the successful management of chronic diseases. Objective tools to track oral medication adherence are either lacking, expensive, difficult to access, or require additional equipment. To improve medication adherence, cheap and easily accessible objective tools able to track compliance levels are necessary. A tool to monitor pill intake that can be implemented in mobile health solutions without the need for additional devices was developed. We propose a pill intake detection tool that uses digital image processing to analyze images of a blister to detect the presence of pills. The tool uses the Circular Hough Transform as a feature extraction technique and is therefore primarily useful for the detection of pills with a round shape. This pill detection tool is composed of two steps. First, the registration of a full blister and storing of reference values in a local database. Second, the detection and classification of taken and remaining pills in similar blisters, to determine the actual number of untaken pills. In the registration of round pills in full blisters, 100% of pills in gray blisters or blisters with a transparent cover were successfully detected. In the counting of untaken pills in partially opened blisters, 95.2% of remaining and 95.1% of taken pills were detected in gray blisters, while 88.2% of remaining and 80.8% of taken pills were detected in blisters with a transparent cover. The proposed tool provides promising results for the detection of round pills. However, the classification of taken and remaining pills needs to be further improved, in particular for the detection of pills with non-oval shapes.
Localization of Stereovision for Measuring In-Crash Toeboard Deformation
Authors: Zhang Wei , Furukawa Tomonari , Nakata Azusa , Hashimoto Toru
Published: April 2022

This paper presents a technique to localize a stereo camera for in-crash toeboard deformation measurement. The proposed technique designed a sensor suite to install not only the stereo camera but also initial measurement units (IMUs) and a camera for localizing purpose. The pose of the stereo camera is recursively estimated using the measurement of IMUs and the localization camera through an extended Kalman filter. The performance of the proposed approach was first investigated in a stepwise manner and then tested in controlled environments including an actual vehicle crash test, which had successfully resulted in measuring the toeboard deformation during a crash. With the oscillation motion in the occurrence of the crash captured, the deformation of the toeboard measured by stereo cameras can be described in a fixed coordinate system.
On Slip Detection for Quadruped Robots
Authors: Nisticò Ylenia , Fahmi Shamel , Pallottino Lucia , Semini Claudio , Fink Geoff
Published: April 2022

Legged robots are meant to autonomously navigate unstructured environments for applications like search and rescue, inspection, or maintenance. In autonomous navigation, a close relationship between locomotion and perception is crucial; the robot has to perceive the environment and detect any change in order to autonomously make decisions based on what it perceived. One main challenge in autonomous navigation for legged robots is locomotion over unstructured terrains. In particular, when the ground is slippery, common control techniques and state estimation algorithms may not be effective, because the ground is commonly assumed to be non-slippery. This paper addresses the problem of slip detection, a first fundamental step to implement appropriate control strategies and perform dynamic whole-body locomotion. We propose a slip detection approach, which is independent of the gait type and the estimation of the position and velocity of the robot in an inertial frame, that is usually prone to drift problems. To the best of our knowledge, this is the first approach of a quadruped robot slip detector that can detect more than one foot slippage at the same time, relying on the estimation of measurements expressed in a non-inertial frame. We validate the approach on the 90 kg Hydraulically actuated Quadruped robot (HyQ) from the Istituto Italiano di Tecnologia (IIT), and we compare it against a state-of-the-art slip detection algorithm.
Tenure-Based Housing Spatial Patterns and Residential Segregation in Guangzhou under the Background of Housing Market Reform
Authors: Liu Wangbao
Published: April 2022

China’s urban housing distribution system has been transformed from a redistribution system to a market-oriented distribution system, which has profoundly affected the ways and opportunities for urban residents to obtain housing resources and has triggered a large-scale reconstruction of urban residential social space. Based on the national 5th and 6th census data of Guangzhou, this paper analyzes the spatial patterns of housing tenure and tenure-based residential segregation in 2000 and 2010 with the research aim of analyzing the internal logic of urban housing distribution and residential segregation in urban China using Guangzhou as an example. The study finds that the home ownership rate in Guangzhou dropped from 62.31% in 2000 to 49.72% in 2010, with the percentage of social housing particularly low. The index of evenness and concentration is used to analyze tenure-based residential segregation. The results show that the tenure-based residential segregation index in 2000 and 2010 is between 0.4 and 0.6, which implies that residential segregation is basically moderate and that social housing is more segregated than open market housing. On the whole, market mechanisms have gradually played a fundamental role in tenure-based residential restructuring and segregation since 2000, and governmental and institutional factors also significantly influence such elements.
An Adaptive Designer Network Model and Its Robustness Research
Authors: Liu Dianting , Huang Kangzheng , Wu Danling , Wang Peng , Cui Qi , Zhang Shenglan
Published: April 2022

The designer network is the carrier for designers to carry out product design tasks, and the study of its evolution helps to accurately identify the designer team. The uncertainty of whether the designer chooses to keep in touch with other members of the network, its nonlinearity on the overall performance of the network and the external interference of the network, etc., increase the complexity of the designer network, which is not conducive to the development of product design tasks. Therefore, it is very interesting and important to study the co-evolution mechanism of the designer’s network structure and the designer’s opinion. This paper analyzes the Deffuant opinion dynamics model, considers the asymmetry of nodes in the network caused by the designer’s unequal relationship (the number of node links is different), and the difference in the degree of acceptance of other people’s opinions by different individuals, and improves the Deffuant model. Then combining the improved Deffuant model with the BA (Barabasi–Albert) model, a DBA (Deffuant and BA Adaptive) model was proposed that integrates opinion update, broken edge and reconnection, and opinion changes. On this basis, this paper designs a virtual network through the crowdsourcing of a certain product. The adjacency matrix of this network is symmetric, and corresponding comparative experiments are carried out on this network. The analysis of test results shows that under six different deliberate attacks, the DBA model is more robust than the BA model. In addition, the average shortest path of the DBA network will vary with the parameters. The proposed integrated DBA model has important guiding significance for building a robust designer network.
Design and Optimization of Combined Cooling, Heating, and Power Microgrid with Energy Storage Station Service
Authors: Ning Nan , Liu Yu-Wei , Yang Hai-Yue , Li Ling-Ling
Published: April 2022

This study aims to symmetrically improve the economy and environmental protection of combined cooling, heating and power microgrid. Hence, the characteristics of configuration ways of energy storage devices in traditional combined cooling, heating and power systems are analyzed, and a scheme for the operator to establish an energy storage station is designed. An improved aquila optimizer for the optimal configuration of the system is proposed to symmetrically enhance the economic and environmental protection performance. The feasibility of the proposed scheme is verified through experiments in three different places. The results show that the economic cost and exhaust emission of the system with energy storage station are reduced to varying degrees compared with the system with energy storage equipment alone and the system without energy storage equipment based on symmetry concept. Especially in Place 1, the scheme with energy storage station in the system can reduce the electric energy purchased from power grid by 43.29% and 61.09%, respectively, compared with other schemes. This study is conducive to promoting the development of clean energy, alleviating the energy crisis, reducing the power supply pressure of power grid, and improving the profits of operators by symmetrically considering the economic and environmental performance of the system.
Hybrid Sparrow Clustered (HSC) Algorithm for Top-N Recommendation System
Authors: Sharma Bharti , Hashmi Adeel , Gupta Charu , Khalaf Osamah Ibrahim , Abdulsahib Ghaida Muttashar , Itani Malakeh Muhyiddeen
Published: April 2022

Recommendation systems suggest relevant items to a user based on the similarity between users or between items. In a collaborative filtering approach for generating recommendations, there is a symmetry between the users. That is, if user A has similar interests with user B, then an item liked by B can be recommended to A and vice versa. To provide optimal and fast recommendations, a recommender system may generate and keep clusters of existing users/items. In this research work, a hybrid sparrow clustered (HSC) recommender system is developed, and is applied to the MovieLens dataset to demonstrate its effectiveness and efficiency. The proposed method (HSC) is also compared to other methods, and the results are compared. Precision, mean absolute error, recall, and accuracy metrics were used to figure out how well the movie recommender system worked for the HSC collaborative movie recommender system. The results of the experiment on the MovieLens dataset show that the proposed method is quite promising when it comes to scalability, performance, and personalized movie recommendations.
Intelligent Radio Frequency Identification for URLLC in Industrial IoT Networks
Authors: Zhang Tiantian , Ren Pinyi , Xu Dongyang , Ren Zhanyi
Published: April 2022

In the era of Industry 4.0, there are many emerging industrial Internet of Things (IIoT) applications that require ultrareliable and low-latency communications (URLLCs), such as time-sensitive networking (TSN), status reporting, and remote control. With the deployment of massive intelligent devices in IIoT networks, providing security for device physical-layer access is a challenging issue, especially for URLLC applications with strict latency and reliability constraints. We thus developed an intelligent radio frequency identification (RFI) framework to provide a lightweight and energy-efficient physical-layer access scheme for URLLCs via leveraging unique hardware-level imperfections of transmitter. We propose a novel semisupervised-learning (SSL) algorithm to realize intelligent RFI in URLLCs scenarios. One-dimensional network construction is also exploited to improve the accuracy of the proposed SSL algorithm. On the basis of the proposed RFI framework, we analyze the overall uplink transmission error probability and network availability of URLLCs with massive MIMO, which can achieve comparable symmetry performance with that of downlink, and experimental evaluation is also provided to gain comprehensive insight on RFI. Numerical and experimental results demonstrate the effectiveness of our proposed RFI framework and the impact of channel correlation, and provide design guidelines for supporting the radio frequency identification of URLLC applications in IIoT systems.
Association between Environmental Tobacco Smoke Exposure and Adaptive Behavior in Individuals with Autism Spectrum Disorder
Authors: Szapuova Zofia Janik , Argalasova Lubica , Vondrova Diana , Jansakova Katarina , Belica Ivan , Kopcikova Maria , Babinska Katarina , Ostatnikova Daniela
Published: April 2022

The study focuses on current issues of adaptive behavior in individuals with autism spectrum disorder (ASD) and on the possible risk factor of environmental tobacco smoke (ETS). Children examined at the Academic Research Center for Autism (ARCA) in Bratislava were involved in the study. The study sample included 84 children (71 boys) with ASD (average age 5.35 years) and a non-ASD group of 24 children (20 boys; average age 8.10 years). The “ETS Questionnaire” focused on the detection of parental smoking habits and other ETS exposures. The concentrations of cotinine in urine were measured by ELISA kit. A significant delay in adaptive behavior of children with ASD in comparison with the non-ASD group was identified. The significant differences were in adaptive behavior, communication, and everyday skills. Children with ASD were more likely to be exposed to ETS, especially in the household. Good agreement was found between objective and subjective ETS exposure indicators (kappa = 0.613). Self-reported exposure to ETS corresponded significantly with the median levels of urinary cotinine. In addition to evaluation and assessment of the quality of adaptive behavior, an important goal of further research should be to identify, investigate, and eliminate environmental factors that interfere with adaptive behavior.
Vaccine Hesitancy in Saudi Arabia: A Cross-Sectional Study
Authors: Alaamri Olfat , Okmi Ezzuddin A. , Suliman Yasser
Published: April 2022

(1) Background: vaccine hesitancy can put the public’s health at risk from vaccine-preventable diseases. This study aimed to address vaccine hesitancy in Saudi Arabia and understand the problem’s magnitude and causes. (2) Methods: this was a descriptive observational study using quantitative and qualitative evaluation methods conducted in Saudi Arabia between December 2020 and February 2021. Public survey forms, exit interviews, and healthcare professional survey forms were used. (3) Results: our study involved 2030 public survey participants, 119 exit interviews of caregivers, and 500 healthcare professionals, demonstrating that vaccine hesitancy was relatively low. Ninety percent of the participants agreed that it was essential for everyone to receive the recommended vaccines with their children (p < 0.001), 92% believed that vaccines are safe for their children (p < 0.001), 91% of the participants agreed to give their new children all the recommended doses (p < 0.001), 86% welcomed mass/school vaccination campaigns (p < 0.001), and 81% were willing to pay for additional vaccines for themselves and their children (p < 0.001). (4) Conclusions: vaccine hesitancy is low in Saudi Arabia, and a positive attitude toward vaccination was detected among most of the participants. Vaccination decision-making is complex and includes emotional, cultural, social, spiritual, and political aspects.
Can Potato Crop on Sandy Soil Be Safely Irrigated with Heavy Metal Polluted Water?
Authors: Selim Tarek , Elkefafy Samah M. , Berndtsson Ronny , Elkiki Mohamed , El-kharbotly Ahmed A.
Published: April 2022

Heavy metal (HM) accumulation in soil and plants can occur when water contaminated with HMs is used as a source of irrigation (El-Salam Canal, Egypt). In this study, the effect of watering potato crop in sandy soil from a polluted water source under flood irrigation (FI), sprinkler irrigation (SI), and surface drip irrigation (DI) on the transport of the HMs copper (Cu), manganese (Mn), lead (Pb), and zinc (Zn) in the root zone was experimentally investigated. HM concentrations in potato plant parts was also determined. The field experiments were conducted in a completely randomized block with three replicates for each irrigation method by using nine field lysimeters. Soil and plant samples were collected at the end of the growing season to determine their HM content. The results showed that regardless of irrigation method, irrigation with HM contaminated water raised HM concentrations in both soil and potato plants. DI produced the highest concentrations of most HMs (Cu, Mn, and Pb) in the upper soil layer (0–40 cm) and highest Cu, Pb, and Zn concentrations in plant tubers as well. Maximum Zn concentration in the upper soil layer and maximum Mn concentration in plant tubers occurred under SI. The maximum concentrations of Cu, Mn, Pb, and Zn in both the upper soil layer and plant tubers were 12.0, 140.0, 11.6 and 67.9 mg/kg and 6.3, 9.4, 2.3 and 23.9 mg/kg, respectively. However, FI produced the highest concentrations in the deep soil layer (40–60 cm) and the least concentration of HMs in plant tubers. These concentrations were 18.8, 203.8, 13.3 and 70 mg/kg and 4.0, 6.0, 0.6 and 17.1 mg/kg in soil and plant tubers for Cu, Mn, Pb, and Zn, respectively. The maximum concentrations of HMs in soil and potato plants were lower than the maximum permissible limits. Therefore, El-Salam Canal water appears not to be harmful in the short term. However, as shown in the results, HM accumulation depends on irrigation technique; thus, more studies are needed to determine harmful effects in the long term.
Modelo de selección del personal en el departamento de ciencias jurídicas, Universidad Técnica de Manabí
Authors: Poggi Cedeño Edgar Alfredo , Macías Barrezueta Martha
Published: April 2022

El objetivo de la investigación es identificar un modelo de selección del personal en el departamento de ciencias jurídicas de la Universidad Técnica de Manabí (UTM), el cual cumpla la función, la ejecución de procesos y busquen perfilar un aporte al modelo de los recursos humanos ya existentes. Se realizó un levantamiento de datos a los 40 profesionales que laboran dentro de esta unidad, se conceptualizo con los métodos deductivos, correlacionales, exploratorio, descriptivo y estadístico. Los resultados indicaron que los profesionales que se integren al departamento de ciencias jurídicas deben tener un perfil profesional proactivo, conocimientos actualizados, la especialización un requisito para el desarrollo y destreza de la enseñanza. Uno de los componentes de la investigación propone un modelo basado de los resultados y factores asociados a la gestión del recurso humano, se considera como parte técnica del aporte situacional en el proceso de selección de personal.

 

Palabras clave: Modelo de recurso humano, selección de personal, recursos humanos, perfil profesional.
PENGARUH RECEIVABLE TURN OVER, CASH RATIO, DAN DEBT TO ASSET RATIO DALAM MENILAI NET PROFIT MARGIN (NPM) PT. INTI UNITED UTAMA PADA PERIODE 2014-2017
Authors: Fellycia Fellycia
Published: April 2022

Tujuan diadakannya penelitian ini adalah untuk menguji dan menganalisis bagaimana pengaruh Receivable Turn Over, Cash Ratio, dan Debt To Asset Ratio dalam menilai Net Profit Margin Pada PT. Inti United Utama. Populasi yang digunakan dalam penelitian ini adalah laporan keuangan PT. Inti United Utama dengan menggunakan teknik sampel jenuh dan sampel yang digunakan adalah 48 sampel. Metode yang digunakan dalam penelitian ini adalah kuantitatif, jenis penelitian yang digunakan adalah kuantitatif, sifat penelitian ini adalah kausal dan jenis data adalah primer. Metode analisis data yang digunakan adalah regresi berganda. Teknik pengumpulan data menggunakan teknik pengambilan data langsung dari perusahaan  PT. Inti United Utama. Hasil penelitian ini menunjukkan bahwa Receivable Turn Over, Cash Ratio dan Debt to Asset Ratio secara simultan berpengaruh dan signifikan Terhadap Net Profit Margin Pada PT. Inti United Utama Pada Periode 2014-2017. Secara parsial Receivable Turn Over berpengaruh negatif dan signifikan terhadap Net Profit Margin. Secara parsial Cash Ratio berpengaruh positif dan signifikan terhadap Net Profit Margin. Secara parsial Debt to Asset Ratio berpengaruh negatif dan signifikan terhadap Net Profit Margin. Hasil uji koefisien determinasi menunjukkan  26,2% dari variabel Net Profit Margin yang dapat dijelaskan oleh variabel Receivable Turn Over, Cash Ratio, dan Debt to Asset Ratio.
Pengaruh current ratio (CR), Receivable turn over (RTO), dan Debt to equity ratio (DER) terhadap return on assets (ROA) pada perusahaan subsektor pedagangan besar dan perdagangan eceran yang tercatat dalam bursa efek indonesia (BEI)
Authors: Erica Erica
Published: April 2022

The objective of the study is to examine and analyze the effect of current ratio, receivable turnover and debt to equity ratio on return on assets in the large trading and retail trade subsector companies listed on the Indonesia Stock Exchange in 2013-2017. The research used a quantitative research method; this type of research is quantitative research using secondary data obtained from the Indonesia Stock Exchange. The research nature was to find out the relationship between variables. The research populations were all large trading and retail trading subsector companies listed on the Indonesia Stock Exchange consisting of 62 companies. The research samples were drawn by using a purposive sampling technique using certain criteria that the research samples consisted of 19 companies. The research data were analyzed by using multiple linear analysis, classic assumption tests including normality test, multicollinity test, autocorrelation test, and heterokedasticity test, as well as the F test and the T test. Partially, the result showed that the current ratio and receivable turnover positively and positively affected and significant on return on assets while the debt to equity ratio has a negative and significant effect on return on assets. The simultaneous testing showed that the current ratio, receivable turn over and debt to equity ratio affected return to assets. The results of the coefficient of determination showed that 62% of the variable return on assets can be explained by the variable current ratio, receivable turn over and debt to equity ratio.
PENGARUH PENDAPATAN ASLI DAERAH (PAD), BELANJA DAERAH, ANGKATAN KERJA, KEMISKINAN TERHADAP PRODUK DOMESTIK REGIONAL BRUTO (PDRB) DI KABUPATEN/KOTA PROVINSI SUMATERA UTARA PADA PERIODE 2017–2020
Authors: Rajagukguk Elin Awanta
Published: April 2022

ABSTRACT

This observation is useful in examining how the impact of Original Local Government Revenue, Expenditure, Labor Force, and Poverty on the Gross Regional Domestic Product (GRDP). The data used in the form of publication information for the Province of North Sumatra in Figures 2021 every year is published on the BPS website for the Province of North Sumatra.. The sampling method is taken from saturated sampling. The test method uses multiple linear regression, and classical assumption tests, namely normality test, multicollinearity test, autocorrelation test, heteroscedasticity test, T test, F test and coefficient test (R2). The test results in this study are (1) Original Local Government Revenue does not have a significant impact on Gross Regional Domestic Product. (2) Expenditures have a significant negative effect on Gross Regional Domestic Product. (3) Labor force and poverty have a positive and significant effect on Gross Regional Domestic Product. (4) Original Local Government Revenue, Expenditure, Labor Force and Poverty have a simultaneous impact on Gross Regional Domestic Product. By obtaining the Ajuted Rsquare value of 37.3% and the result of 62.7 is the remaining influence of other variables or other factors.

 

Keywords: OLGR, Expenditure, Labor Force, Povert, GRDP
PENGARUH PERGANTIAN AUDITOR, JENIS INDUSTRI, ANAK PERUSAHAAN (SUBSIDIARY), KEPEMILIKAN PUBLIK DAN LEVERAGE TERHADAP AUDIT DELAY PADA PERUSAHAAN PERDAGANGAN DAN INVESTASI YANG TERDAFTAR DI BEI PADA TAHUN 2016 - 2019
Authors: Tandi Alex Sander
Published: April 2022

ABSTRAK

The research is intended to analyze and examine whether changes in auditors, types of industries, subsidiary, public ownership, and leverage affect audit delay on the commerce and investments listed in the Indonesian stock exchange during 2016-2019.  This research using analysis method and through the causal relationship of as many as 79 sample results are selected, where 316 observations are passed conditional. Sample retrieval technique obtained from an impressive sampling. Testing of the hypotheses and data analysis with regression methods obtained from SPSS 20 partial and simultaneously indicates that changes in auditors, types of industries, subsidiary companies, public ownership and leverage did not affect, and little effect on auditory delays in trading and investment from 2016 to 2019 recorded in the Indonesian stock exchange.

Key words: change of auditors, types of industries, subsidiaries, public ownership,leverage, audit delay
PENGARUH TEKANAN ANGGARAN WAKTU,ETIKA AUDITOR DAN INDEPENDENSI AUDITOR TERHADAP KUALITAS AUDIT PADA KAP WILAYAH MEDAN
Authors: Jenny Jenny zain
Published: April 2022

Abstract

This study discusses the effect of time budget pressure, auditor ethics and auditor independence on audit quality. This research was conducted in 9 Public Accounting Firms in the Medan area. The sample technique used is simple random sampling. The data collection method in this study was conducted by survey or distributing questionnaires. The results of this study indicate that simultaneously time budget pressure, auditor ethics and independence have a significant effect on audit quality. Partially, time budget pressure has no effect on audit quality, auditor ethics has a positive effect on audit quality, and independence has a positive effect on audit quality.
Effectiveness of the Breaking Ground Programme in Transforming Parenting Skills and Practice
Authors: Wong Melanie , Beekmans Tania , Taliaoa Fuatino , Oades Liam M
Published: April 2022

The Breaking Ground programme was an 18-month pilot programme to support families and parents in a mana-enhancing process while developing parenting skills and practices, focused on intensive family intervention. Practitioners worked alongside families who were on a trajectory towards having their children placed in state care, with the goal of preventing entry to such care. This research uses a case-study methodology with data collected through interviews with social workers and families involved in the programme. The aims of this research were: 1) to examine the effectiveness of social workers working with families on the Breaking Ground programme; and 2) to examine the effectiveness of social workers providing cultural support for the families on the programme.
Non-regulated Home Support Worker role in medication support and administration: A scoping review of the literature prepared for the Home & Community Health Association
Authors: Roy Dianne E. , McKechnie Roslyne C.
Published: April 2022

The aim of this literature review is to identify and critique literature relating to current policy, guidelines and practice of non-regulated caregivers in relation to medication while they are working with clients in their own homes. The scope of this review comprises medication administration and medication support, which includes medication prompting and assisting the client to take their medication. Out of scope in this review is medication management. The review draws on relevant Aotearoa New Zealand statutes, standards and practice guidelines related to medication support and administration, District Health Board (DHB) policies, and education and training recommended and/ or available to Home Support Workers (HSWs). Relevant published research and international guidelines are also included.
Inequalities for Women in Science, Technology and Innovation
Authors: Gursch Sarina , Urak Katja , Herold Michael , Kutschera Stefan , De los Rios Perez Silvia , Garcia-Betances Rebeca , Cabrera-Umpierrez Maria , Ursa Yolanda , Slany Wolfgang , Krnjic Vesna
Published: April 2022

There is still a tangible inequality between men and women in many areas of daily life around the world, including professional fields and educational careers. The objective of this study was to analyze the different inequalities in Europe and third countries in America, Asia and Africa regarding the involvement of women and men in education and employment. This study focused on the areas related to Science, Technology and Innovation (STI), three of the most relevant and important areas for the future development of society. The study presented in this paper started with the initial question: "Are there inequalities between women and men in the fields of Science, Technology and Innovation?" This question was followed by an in-depth examination of datasets and studies on women and men who are learning, working, or hold leadership positions in the STI fields. Data and numbers were collected on the workforce, students in higher education, and professional fields. These served to determine and verify the state of the art for women in the fields of STI. Based on the results, presented in the paper, statements can be made regarding inequalities for women in the field of STI. Several efforts are being made in order to promote gender equality in STI. In fact, this has become a strategic issue in Europe, since the Council of the European Union, in its conclusions, invited the Commission and the Member States to consider including the gender perspective within the policy dialogues in bilateral and multilateral agreements with third countries in the STI area.  Moreover, several initiatives have been implemented in recent years as part of the strategy for the European Research Area to promote gender equality in research and innovation. One of these initiatives is the Gender STI project, a European research-funded project that aims to integrate gender perspectives in STI into dialogues between Europe and third countries. As part of the initial activities of the project, this study aims to build a deep understanding on the current status of gender equality in STI in these regions and how the gender perspective is currently addressed in policy dialogues.
MODERN APPROACHES TO USE THE LEASING INSTRUMENT IN THE SPHERE OF HEALTH CARE
Authors: Nurtdinov Ilgiz , Nurtdinova A.
Published: April 2022

The dynamics of the development of medical services, especially private ones, increases the demand for high-tech medical equipment. The purchase of medical equipment is the most important issue for any medical institution, and especially for a private medical company. Renovation of medical equipment in public and private clinics will allow providing the latest treatment methods, providing modern and high-quality medical services. Modern medical technology can give impetus to the development of medical tourism in our country. A tool for acquiring modern equipment can be leasing, in which private and public medical institutions have the opportunity to get medical equipment for use, while not investing quite large sums of money in its purchase. At the same time, they receive certain benefits: for example, by reducing the tax base of their activities. This provides for purposeful and socially oriented activities, as health care is a public good. A special place in the article is given to the analysis of the current state of the leasing business in the context of medical equipment. It is the dynamics of changes in the value of the portfolio of new business of leasing companies that shows the demand for this service with an increase in the number of private clinics, which include large investors.