bluuebunny/crossref_metadata_2025 huggingface dataset:
Tema dan Gaya Bahasa Puisi Siswa SMP: Kajian Struktural
Authors: Hidayatullah Ahmad
Published: August 2021

Penelitian ini bertujuan untuk menemukan data tentang tema serta gaya bahasa yang terdapat dalam sejumlah puisi karya siswa kelas VIII SMP Islam Daar El Arqam Tangerang. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan teknik struktural. Berdasarkan hasil penelitian dapat diketahui, bahwa tema dalam puisi siswa kelas VIII SMP Islam Daar El Arqam meliputi tema tingkat fisik sebanyak 2 buah, tema tingkat organik sebanyak 1 buah, tema tingkat sosial sebanyak 12 buah, tema tingkat egoik sebanyak 5 buah, dan tema tingkat divine sebanyak 7 buah. Gaya bahasa dalam puisi puisi siswa kelas VIII SMP Islam Daar El Arqam yang meliputi gaya bahasa metafora sebanyak 1 buah, gaya bahasa simile sebanyak 7 buah, gaya bahasa personifikasi sebanyak 4 buah, gaya bahasa metonimi sebanyak 1 buah, gaya bahasa sinekdos sebanyak 1 buah, gaya bahasa hiperbola sebanyak 18 buah, gaya bahasa retoris sebanyak 4 buah, gaya bahasa repetisi sebanyak 8 buah, gaya bahasa paralelisme sebanyak 20 buah, dan gaya bahasa paradoks sebanyak 3 buah. Hasil penelitian ini dapat digunakan sebagai salah satu media pembelajaran tentang apresiasi puisi untuk siswa SMP.
Washback in EFL Writing Courses: A Reflective Teaching at English Education Study Program of Teacher Training and Education Faculty of Universitas Maritim Raja Ali Haji
Authors: Nopita Dewi
Published: August 2021

Washback is one of the principles of language assessment. It is the effects of an assessment on teaching and learning prior to the assessment itself, that is, on preparation for the assessment (Brown, 2004). This article aims at describing washback in EFL writing courses at English study program of teacher training and education faculty of Universitas Maritim Raja Ali Haji (UMRAH). The description was got from my own experiences and another writing lecturer’s. To get a more detail description from another lecturer, I interviewed him and his students dealing with the assessment done during the course as well as its impact towards the teaching and learning. Futhermore, I did observation on the improvement of the students’ task and test scores. Finally, it was found that in writing courses at English Education Study Program of Teacher training and Education Faculty (FKIP) of UMRAH, washback did contribute to the quality of teaching and learning since it provides feedback for both the instructors and the students. The feedback helps the instructors to plan a better teaching as well as helps students to do a better learning. The form, content, focus and delivery of writing assessments (tasks and tests) administered during the course determine the way it is taught and the way the students learn. As a result, these features in turn tend to affect the success of the course.
Adjacency Pairs in Ellen DeGeneres’ Talk Show
Authors: Yolannisa Weby
Published: August 2021

Talk Show is a program that basically deals with a conversational discussion concerning latest events in different aspects of life; social, economy, education, life style, love- life etc. From the conversation uttered by speakers, there are some patterns that they automatically produced, called adjacency pairs. Therefore, this study focused on the adjacency pairs in the conversation between the host (Ellen De’Generes) and the guest (Bill Gates) in Ellen De’Generes’ Talk Show. The aims of the research were (1) to describe and analyze types of adjacency pairs in the conversation between Ellen DeGeneres and Bill Gates, and (2) to describe and analyze the preference structure of adjacency pairs in the conversation between Ellen DeGeneres and Bill Gates. The main data of the research were the video and the script of the conversation between Ellen De’Generes and Bill Gates. This study used qualitative approach in investigating the problem in order to get the descriptive data after spoken and written data have been analyzed. In analyzing adjacency pairs and the preference structure of adjacency pairs, the researcher used the theory of conversation analysis (CA) as the basic theory. From the data, it was found that there were 11 adjacency pairs that consisted of 1 pair of assessment – agreement, 2 pair of assertion – agreement, 1 pair of assertion-disagreement, 6 pairs of question-answer, and 1 pair suggestion-acceptance in the conversation. Last, there were 11 data of the preference structure which consisted of 10 data included into the preferred structure from second pair part and 1 data included into the dispreferred structure from second pair part.
The Formation of a Stable Political Governance: Structural-Functional and Morphological Analysis
Authors: Tumanov A. D.
Published: August 2021

The purpose of the article is to implement a systematic analysis of the factors of the formation of a stable system of political governance. To clarify the functions and structure of a stable political system, the characteristics of stability are highlighted, according to which the political system: has signs of legitimacy; is able to cope with the threat of illegitimate violence; supports the constitu-tional system; reproduces a model of behavior based on stability. Methodologically, the article is based on the works of classical and modern scientists (P. M. Khomyakov, M.A. Gaydes, I.B . Rodionov, A. A. Khomiakov). Makarycheva), devoted to the systematic analysis of political systems. The paper also uses morphological analysis, analysis of political eﬃciency, and in the ﬁnal part — the method of state-management design. The author comes to the conclusion that the functions and structure of the modern political system should be considered from the point of view of the deﬁni-tions of “political stability”, viewed through the prism of the absence of political threats, adaptive irremovability of political subjects and the balance of political forces. Political stability implies that the distribution of resources in society involves not only the institutional subsystem of the political system, but also the functional, regulatory and ideological subsystems. Morphological analysis demonstrates that a stable political system is characterized by a balanced interaction of subsystems, in which at least the institutional, regulatory and functional subsystems jointly determine the process of functioning and development of the political system. Stability is the basis and guarantee of po-litical development in the modern world, and stability is not contrary to innovative development or development in general. Both stability and development are the basic conditions for the development of a modern political system, methods of avoiding negative adaptation in the global environment. Stability is not synonymous with closeness — on the contrary, it implies horizontal and vertical mobility, a constitutional system, and a focus on maintaining the activity of political actors. At the same time, all these processes cannot be allowed to take their course and develop outside the political control of the vertical structures of power. Integrity as a system-wide property is an integral basis for the stability of the political system.
The Economic Security Assessment of a Road Facility Enterprise
Authors: Shirko L. M.
Published: August 2021

The purpose of the article is to identify areas for improving the activities of a road enterprise based on a comprehensive assessment of the level of economic security of the enterprise.

Methods. As research methods, the article uses analysis, synthesis, deduction, induction, system analysis, comparative analysis, strategic management tools.

Results. The author proposes an interpretation of the economic security system as a type of functional strategy of an enterprise, substantiates indicators for assessing the level of eco-nomic security of an enterprise. Eﬀectively for practice, the directions of increasing the eco-nomic security of the enterprise have been identiﬁed.

Scientiﬁc novelty. The novelty of the author’s approach lies in the application of the balanced scorecard methodology to the construction of indicators for assessing the level of economic security of an enterprise.
Contours of Resistance: The Postcolonial Female Subject and the Diaspora in the Punjabi Short Story
Authors: Gill Yubee
Published: August 2021

Diaspora literature and theory offer significant critiques of traditional ideas regarding nation-states, identities and dominant cultures. While it is true that the literature of the diaspora has been receiving increasing attention as of late, it is worth noting that works written in the diasporans’ native languages are generally not included in wider discussions about the more complex issues related to the diaspora. As an initial corrective for this deficiency, this article explores selected stories in Punjabi, paying special attention to issues relevant to the lives and experiences of women in diaspora. Diasporic conditions, as most of these stories seem to assert, can be painful for women, but even while negotiating within a diverse system of values, many of them eventually discover possibilities for independence and growth. Such personal improvements are attainable due to their newfound economic liberation, but hard-won economic independence comes with a price. The inclusivity implied by identitary hyphens (i.e. Chinese-American; Mexican-American, etc.), so celebrated in diaspora writings in English, are almost as a rule missing in the fictional accounts studied here. In these accounts, an essential feature of diasporic subjectivity is the double sense of “Otherness” strongly felt by people who, having extricated themselves from the cultural demands of their original group, are not unchallenged members of the dominant culture.
The Luit in Bhupen Hazarika’s Songs: A Metaphor for Exploring Assam’s Linguistic and Ethnic Politics
Authors: Borah Jayashree
Published: August 2021

The river Brahmaputra, also known as Luit, has always occupied an important place in the cultural mindscape of the people of Assam, a state in the northeast of India. A source of great pride because of its sheer size and the myths and lore associated with it, it has nevertheless brought untold misery to people over the years because of annual flooding. Authors and musicians of the land have found in the Luit an apt metaphor to tell stories of love, loss, belonging and pain. In the songs of Bhupen Hazarika (1926-2011), a renowned music composer from Assam, the Brahmaputra becomes a character through which the poet expresses both his anguish at the sufferings of the masses and his joy at the all- embracing nature of the valley. In songs like “Mahabahu Brahmaputra”, Hazarika tries to appeal to the people of Assam to maintain harmony and promote the land as one of plurality and hospitality. This song becomes significant when seen in the context of the Assam movement (a six-year long agitation to halt the illegal migration of people from neighbouring Bangladesh) and Hazarika’s own conflicted attitude towards it. This article is an attempt to examine how the Luit has been represented in a selection of Hazarika’s songs – the ways the river becomes a potent presence of deeply political and social overtones and a metaphor to underscore the turbulent history of Assam.
Genetic variability in bulgarian melon collection - flowering types and fruit quantitative traits
Authors: Ivanova Zhana , Velkov Nikolay
Published: August 2021

Cucumis melo L. is characterized with a great polymorphism according to many
agronomical features. Study the variability of melon flowering and fruit
traits is an initial step in the breeding program. The current study aimed
to identify the genetic variability in the melon collection according to
flowering and fruit traits in order to be used in breeding programs. It was
evaluated fifty melon genotypes belong to different groups - cantalupensis,
reticulatus, makuwa, inodorus, and agrestis. The studied collection consists
of Bulgarian old cultivars, hybrids, landraces, PI, and introduced lines.
Investigated genotypes were characterized by nine quantitative fruit traits
- days to flowering, sex expression, days to ripening, fruit length, fruit
diameter, flesh thickness, fruit weight, seed cavity diameter, and total
soluble solids. It was established great variability in studied
characteristics measured by a coefficient of variation from 7.73 to 39.85%.
Significant correlations between fruit length, fruit diameter, flesh
thickness, cavity diameter, and fruit weight were established. Principal
component analysis grouped variables into three components which explain
69.89% of the total variation. Cluster analysis divided genotypes into six
groups of similarities. Among the genotypes examined, they have a relatively
high level of variability and their polymorphism could be used in a breeding
program aimed at combining valuable characters.
Genotypic variability of root and shoot traits of bread wheat (Triticum aestivum L.) at seedling stage
Authors: Blazic Milica , Dodig Dejan , Kandic Vesna , Djokic Dragoslav , Zivanovic Tomislav
Published: August 2021

The evaluation of the embryonic root and stem of bread wheat (Triticum
aestivum L.) in the early stage of development (seedling stage) can be a
powerful tool in wheat breeding aimed at obtaining progenies with a greater
early vigour. It is revealed that genotypes with faster early vigour have
produced higher biomass and grain yield. In this study, the evaluation of
traits of the embryonic root and the embryonic stem of 101 bread wheat
genotypes was preformed at the 10-day old seedlings. The following eight
morphological traits of roots and stems were analysed: primary root length,
branching interval, the number of roots, total length of lateral roots,
angle of seminal roots, stem length, root dry weight and the stem dry
weight. Analysed lateral roots included seminal roots. The greatest, i.e.
the smallest variability of observed traits was detected in the branching
interval, i.e. the stem length, respectively. The highest positive
correlation was determined between the primary root length and the total
length of lateral roots. The cluster analysis, based on observed traits,
shows that genotypes were clearly divided into two main clusters, A and B.
The two clusters essentially differed from each other in the values of the
following traits: primary root length, total length of lateral roots, root
dry weight, stem dry weight and the stem length. Genotypes with shorter
primary and lateral roots, lower root and stem dry weight and a shorter stem
were grouped in the cluster B. On the other hand, the cluster A encompassed
genotypes with values of these traits above or around the average. The
values of the remaining analysed traits: the angle of seminal roots, the
number of lateral roots and the branching interval varied greatly between
obtained clusters. The cluster analysis showed the homogeneity of genotypes
originating from Serbia and the region; their values of the root and stem
length and weight were mostly around and below the average. However, the
values of the angle of seminal roots, number of lateral roots and the
branching interval were above average.
Compositional diversity in essential oil of Ziziphora tenuior L. ecotypes
Authors: Dogan Hulya
Published: August 2021

Present study reports a comparative screening of three ecotypes of Ziziphora
tenuior L., sampled from three region with different elevation in middle and
northeastern Turkey, based on their essential oil composition, total
phenolic content and antioxidant capacities. Z. tenuior ecotypes showed
twenty compounds, representing 89.18-91.44% of the essential oil (EOs)
identified by GC-MS. The major components of EOs in ecotypes were pulegone
(37.23-49.12%), and followed by 1,8-Cineole (2.26-7.78%), limonene
(4.20-5.44%), ?-Caryophyllene (3.88-5.11%) and thymol (2.68-4.11%),
respectively. Ecotypes showed variable pulegone content and it was increased
with elevation increase. The total phenolic contents varied among ecotypes
ranged from 21.13 to 27.50 mg of gallic acid equivalent/g EOs. Antioxidant
capacity was determined in vitro using DPPH radical-scavenging and FRAP
(Ferric reducing power) assays and expressed as concentration of each
extract required to inhibit radical by 50% (IC50 and EC50) values that
ranged from 0.80 to 0.97 mg/ml in DPPH and 0.42 to 0.55 mg/ml in FRAP
assays, respectively. Our results indicated that antioxidant capacity
changed among ecotypes. Taking into account the essential oil content, it
seems that to select ecotype was the most appropriate to obtain more
pulegone for this plant from its wild habitat.
Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes
Authors: Tong Xin , Stein Roland
Published: August 2021

Free fatty acids (FFAs) are often stored in lipid droplet (LD) depots for eventual metabolic and/or synthetic use in many cell types, such a muscle, liver, and fat. In pancreatic islets, overt LD accumulation was detected in humans but not mice. LD buildup in islets was principally observed after roughly 11 years of age, increasing throughout adulthood under physiologic conditions, and also enriched in type 2 diabetes. To obtain insight into the role of LDs in human islet β-cell function, the levels of a key LD scaffold protein, perilipin 2 (PLIN2), were manipulated by lentiviral-mediated knockdown (KD) or overexpression (OE) in EndoCβH2-Cre cells, a human cell line with adult islet β-like properties. Glucose-stimulated insulin secretion was blunted in PLIN2KD cells and improved in PLIN2OE cells. An unbiased transcriptomic analysis revealed that limiting LD formation induced effectors of endoplasmic reticulum (ER) stress that compromised the expression of critical β-cell function and identity genes. These changes were essentially reversed by PLIN2OE or using the ER stress inhibitor, tauroursodeoxycholic acid. These results strongly suggest that LDs are essential for adult human islet β-cell activity by preserving FFA homeostasis.
Depression and Diabetes in Workers Across the Life Span: Addressing the Health of America’s Workforce—Behavioral Risk Factor Surveillance System, 2014–2018
Authors: Kaur Harpriya , Scholl Juliann C. , Owens-Gary Michelle
Published: August 2021

OBJECTIVE

Diabetes affects nearly 12.2% of U.S. adults. Comorbid depressive symptoms among U.S. workers with diabetes are associated with increased unemployment and reduced work performance. This study examined the age-group–specific prevalence of depression among U.S. workers with self-reported diabetes and identified factors associated with depression.

METHODS

Data from the 2014–2018 Behavioral Risk Factor Surveillance System were used to examine the prevalence of depression among adult workers with diabetes in the United States. Relationships between depression prevalence and diabetes and demographic, physical, and behavioral risk factors were examined through bivariate and multivariable analyses. Age was categorized into four groups: 18–34, 35–54, 55–64, and ≥65 years.

RESULTS

The overall prevalence of self-reported depression among U.S. workers with diabetes was 17.4–30% higher than among those without diabetes. Workers with diabetes aged 18–34 years had the highest depression prevalence (28.7%) compared with other age-groups. Female workers with diabetes were significantly more likely than male workers to report depression in all age-groups. Young adult workers with diabetes who had another chronic disease were nearly three times more likely to report depression than those without another chronic condition. There were no overlapping patterns of prevalence of diabetes and depression by state.

CONCLUSION

Workers with diabetes are at an increased risk of depression, which can affect their overall health and productivity. These findings indicate that, among those with diabetes, young adult workers and women are most likely to have depression. Employee wellness programs may address the specific needs of individuals with diabetes and depression.
Effect of Diet Quality and Genetic Predisposition on Hemoglobin A1c and Type 2 Diabetes Risk: Gene-Diet Interaction Analysis of 357,419 Individuals
Authors: Zhuang Pan , Liu Xiaohui , Li Yin , Wan Xuzhi , Wu Yuqi , Wu Fei , Zhang Yu , Jiao Jingjing
Published: August 2021

OBJECTIVE: To
assess the interactions between diet quality and genetic predisposition to
incident type 2 diabetes (T2D).

RESEARCH
DESIGN AND METHODS: 357,419
participants with genetic and complete dietary data from the UK Biobank, were
enrolled between 2006 and 2010 and were prospectively followed up to 2017. The genetic risk score (GRS) was calculated on the basis of
424 variants associated with T2D risk and a higher GRS indicates a higher
genetic predisposition to T2D. The adherence to a healthy diet was assessed
by a diet quality score comprising of 10 important dietary components, with a higher score representing a higher overall
diet quality.

RESULTS: 5,663 incident T2D cases were documented
during an average of 8.1 years of follow-up. A significant negative interaction
was observed between GRS and diet quality score. After adjusting for major risk
factors, per SD increment in GRS and diet quality score was associated with a 54%
higher and a 9% lower risk of T2D, respectively. Besides, a simultaneous
increment of 1 SD in both diet quality score and GRS was additionally associated
with a 3% lower T2D risk due to the antagonistic interaction. In categorical
analyses, a sharp reduction of 23% in T2D risk associated with 1 SD increment
in diet quality score was detected among participants in the extremely high GRS
group (GRS>95%). We also observed a strong negative interaction between GRS
and diet quality score on blood HbA1c level at baseline (P<0.001).

CONCLUSIONS: The adherence to a healthy diet was associated with more
reductions in blood HbA1c levels
and subsequent T2D risk among
individuals with higher genetic risk. Our
findings support tailoring dietary recommendations to an individual’s genetic
makeup for T2D prevention.
Lipid droplets protect human β cells from lipotoxic-induced stress and cell identity changes
Authors: Tong Xin , Stein Roland
Published: August 2021

Free fatty acids (FFAs) are often stored in lipid droplet (LD) depots
for eventual metabolic and/or synthetic use in many cell types, such a
muscle, liver, and fat. In pancreatic islets, overt LD accumulation was
detected in humans but not mice. LD buildup in islets was principally
observed after roughly 11 years of age, increasing throughout adulthood
under physiologic conditions, and also enriched in type 2 diabetes. To
obtain insight into the role of LDs in human islet β cell function, the
levels of a key LD scaffold protein, perilipin2 (PLIN2), were
manipulated by lentiviral-mediated knock-down (KD) or over-expression
(OE) in EndoCβH2-Cre cells, a human cell line with adult islet β-like
properties. Glucose stimulated insulin secretion was blunted in PLIN2KD
cells and improved in PLIN2OE cells. An unbiased transcriptomic analysis
revealed that limiting LD formation induced effectors of endoplasmic
reticulum (ER) stress that compromised the expression of critical β cell
function and identity genes. These changes were essentially reversed by
PLIN2OE or using the ER stress inhibitor, tauroursodeoxycholic acid.
These results strongly suggest that LDs are essential for adult human
islet β cell activity by preserving FFA homeostasis.
The Point-Rating Scale for Determining Treatment Tactics in Patients With Adhesive Small Bowel Obstruction
Authors: Sigua B. V. , Zemlyanoy V. P. , Filenko B. P. , Kotkov P. A. , Kalandarova D. Kh. , Kozobin A. A.
Published: August 2021

Relevance. The most practiced method of treating patients with acute intestinal obstruction - urgent surgical intervention - does not guarantee remission, contributing to the progression of morphological changes in the abdominal cavity. From this perspective, a shift in emphasis towards the planned surgical treatment of patients with adhesive disease with the use of the existing anti-adhesive methods after conservative resolution of the intestinal passage disorders looks like a promising direction.

Aim of the study. Improving the results of patients with acute adhesive intestinal obstruction treatment by developing a point-rating scale that allows to highlight groups of patients who are prone to conservative resolution of intestinal passage disorders episode, and, thereby, reduces the proportion of urgent interventions.

Material and methods. The analysis of the 125 patients treatment results (retrospective group) admitted with symptoms of acute adhesive intestinal obstruction was carried out. On this basis, the point-rating scale was developed including a number of factors that have certain value in terms of predicting the probability of conservative therapy success. Subsequently the developed scale was applied in 170 patients (prospective group) as part of treatment tactics implementation aimed at maximally conservative resolution of adhesive intestinal obstruction without negative effect on the immediate results of patients operated in later periods.

Results. The developed point-rating scale made it possible to reduce the frequency of urgent interventions among patients with signs of acute adhesive intestinal obstruction (from 79.2% to 57.6%) due to longer conservative measures — 18.1±17.2 and 11,2±8.7 hours in prospective and retrospective groups, respectively). There was no negative impact on the frequency of resection interventions (12.2 and 16.1% in the prospective and retrospective groups) as well as postoperative complications and overall mortality.

Conclusions. The developed point-assessment scale made it possible to stratify patients in accordance with the probability of conservative therapy success and to justify its continuation for more than 12 hours in low-risk patients. The obtained results allow us to recommend the proposed scale for use in clinical practice.
Shorting Resection and Correction of the Leg Length in the Treatment of Posttramatic Tibial Defects Complicated by Osteomyelitis
Authors: Artemiev A. A. , Ivanov P. A. , Kashoob A. M. , Grigoriev M. A. , Gandzhaliev R. A. , Soloviev Yu. S. , Sysoev I. A.
Published: August 2021

Background.Severe fractures of the shin bones are often accompanied by the formation of defects in the tibia, suppuration and soft tissue necrosis. In the case of surgical treatment of fractures, infectious complications reach 3.6-9.1%. One of the methods of treatment of infected defects is resection of the ends of the tibia with shortening. This operation has proven to be effective in the treatment of fresh fractures. The relevance of the work is due to the prospects of using this technique in the treatment of the consequences of fractures with the formation of infected defects of the tibia.

Aim of the study. Improving the results of treatment of patients with post-traumatic defects of the tibia complicated by osteomyelitis by performing a shortening resection with simultaneous or sequential correction of the segment length.

Material and methods.The results of treatment of 65 patients with diaphyseal post-traumatic tibial defects complicated by osteomyelitis were analysed. They were divided into 2 groups. Group 1 was formed by 31 (47.7%) patients, they underwent shortening resection of the ends of bone fragments in the defect zone with simultaneous lengthening at another level. Group 2 included 34 (52.3%) patients who underwent a shortening resection of the tibia without lengthening. In all cases, the Ilizarov apparatus was used as a fixator.

Results.The technique for assessing the size of the true defect of the tibia was optimized taking into account the initial shortening of the segment and the distance between the proximal and distal fragments after resection of their ends. A treatment regimen was developed depending on the level of localization of the tibial defect, and the results of treatment of patients in the compared groups were assessed.

Conclusion.Shortening resection is an effective treatment for patients with post-traumatic tibial defects complicated by osteomyelitis. Depending on the level of localization of the defect, it is advisable to carry out treatment according to one of two possible options. When the defect is localized in the upper and middle third of the tibia, shortening resection in an isolated form is shown. If the defect is localized in the lower third of the tibia, it is possible to supplement the shortening resection with an osteotomy in the upper third with Ilizarov lengthening.
Evaluation of Cytokine Dynamics in Patients With Multiple and Concomitant Closed Chest Injuries
Authors: Khalyapina A. B. , Parshikov M. V. , Bolotov D. D. , Zhuravlyova G. M. , Yarygin N. V.
Published: August 2021

Aim of the study. An actual problem of the modern approach to the management of patients in the post-traumatic period with the aim of predicting, preventing and treating complications of post-traumatic pneumonia is the assessment of the dynamics of the cytokine profile in this period.

Material and methods. Investigations were carried out at the time of hospitalization prior medical interventions. During the research the following methods were used: clinical, physical, instrumental, follow-up, radiation (MRI, CT, X-Ray), endoscopic, laboratory. Blood was taken from the peripheral vein on the first, third, fifth, seventh and ninth day of hospitalization to determine the interlikin profile. The definition of Proinflammatory cytokines: IL-1, IL-6 and IL-10 in the blood serum performed by ELISA on the immunofermental analyzer Abbott AXSYM using standard kits ProCon (“Protein contour”, St. Petersburg, Russia). Data were processed statistically using Student’s t-test.

Results. Analysis of the results of determination of IL-1 in the serum of patients DK showed that in all stages of the disease, in addition to IV, the contents of this cytokine exceeded the control values in varying degrees of severity. While the levels of IL-1 in the serum of patients with the 1ststage of the disease was 4.0 times; stage 2–3.4 times; the third stage is 1.5 times higher than normal. And only in patients with very severe stage of pneumonia contents IL-1 did not differ from the norm. A similar picture was observed when determining the serum content of patients with a very severe stage of pneumonia, and only in contrast to the level of IL-1 in patients with a very severe stage of pneumonia, the IL-6 content remained significantly higher than normal. So, the content of IL-10 in patients with a very severe stage of pneumonia of stage I, II, III and IV of the disease averaged 330.7±24.5, respectively; 210.5±17.3; 123.4±15.3 and 98.5±12.7 pg/ml (in all cases p<0.05). CONCLUSION The results obtained in a comparative study of contents of proinflammatory cytokines (IL-1, IL-6 and TNF-a) in the blood serum showed that the determination of the spectrum of cytokines in peripheral blood, in our opinion, is the most perspective and can be a key marker for early detection of inflammation. Key words: post-traumatic pneumonii, interlikin profile, peripheral blood serum>˂0.05).

Conclusion. The results obtained in a comparative study of contents of proinflammatory cytokines (IL-1, IL-6 and TNF-a) in the blood serum showed that the determination of the spectrum of cytokines in peripheral blood, in our opinion, is the most perspective and can be a key marker for early detection of inflammation.
Local Hemostatic Agents in Surgical Practice
Authors: Kalinin R. E. , Suchkov I. A. , Bazaev S. B. , Krylov A. A.
Published: August 2021

At present, in emergency surgery, great importance is attached to reliable intraoperative hemostasis, for the achievement of which local hemostatic agents are used. The use of these funds tends to increase. The hemostatic agents are divided on 3 main groups. In turn, each group has its own physical and chemical characteristics and different ways of application. The surgeon have task of choosing and correctly using a specific hemostatic agent in a specific clinical situation, especially an emergency one.
Combined Blunt Splenic Injury in Adults: Modern Approach to Diagnosis and Treatment
Authors: Aleksandrov V. V. , Maskin S. S. , Matyukhin V. V.
Published: August 2021

Background. The high frequency of injuries of the spleen, as well as its important immunocompetent role in the body, dictate the need to develop a standardized approach to the diagnosis and treatment of this category of patients.

Aim. Standardization of the treatment and diagnostic approach for combined blunt splenic injury to improve treatment results.

Material and methods. The analysis of literary sources of Russian and foreign authors on this issue.

Results. The therapeutic and diagnostic algorithm was developed for combined blunt splenic injury based on the severity of the patient, and a detailed description of non-operative and damage control surgical treatment was given.

Conclusion. The use of endovascular interventions in the treatment of splenic injuries, as well as their gradual treatment in conditions of severe polytrauma, helps to reduce mortality.
Experience of Implementation of an Organizational and Methodological Approach to the Description and Standardization of Treatment and Diagnostic Processes in N.V. Sklifosovsky Research Institute for Emergency Medicine
Authors: Fomenko N. S. , Perminov A. Y. , Petrikov S. S.
Published: August 2021

Currently, the issues of improving the quality of medical care and the effectiveness of management are in the focus of attention of heads of medical organizations. Obviously, for the successful management of any complex object, it is necessary to understand the principles of its operation and have a formalized description (model).

This article presents the experience of systemic implementation of the organizational and methodological approach developed by the authors to the description and standardization of the treatment and diagnostic processes of a multidisciplinary hospital.

When writing the work, the methods of system analysis and synthesis were used. Analyzed and systematized the successful experience of the N.V. Sklifosovsky Research Institute for Emergency Medicine on the introduction of the developed organizational and methodological approach into the current activities of a medical institution, as well as the results of its approbation in more than 270 complex medical and diagnostic processes, surgical interventions, active methods of treatment, instrumental and laboratory diagnostics.

The article defines the most important principles for the formation of small groups, the basic values underlying their work, the main motivational factors for the participation of doctors, as well as critical factors for the success of the implementation of the organizational and methodological approach. The experience of its phased implementation is considered: from the processes of the admission department to the processes of medical and intensive care departments; as well as implementation features in the description of diagnostic profile processes.

Based on the results of the implementation of the organizational and methodological approach at the N.V. Sklifosovsky Research Institute for Emergency Medicine, a conclusion was made about its universality and applicability for any medical institution.

In the conclusion of the article, recommendations are formulated for the systemic organization of implementation in a medical institution of the organizational and methodological approach developed by the authors to the description and standardization of treatment and diagnostic processes.
Prediction of Resthenosis After Carotid Endarterectomy by the Method of Computer Simulation
Authors: Kazantsev A. N. , Vinogradov R. A. , Zakharov Yu. N. , Borisov V. G. , Chernyavsky M. A. , Kravchuk V. N. , Shmatov D. V. , Chernykh K. P. , Sorokin A. A. , Baghdavadze G. Sh. , Artyukhov S. V. , Khubulava G. G.
Published: August 2021

The article describes a computer modeling technique that allows predicting the development of restenosis of the internal carotid artery after carotid endarterectomy (CEE). A clinical case has been demonstrated that proves the effectiveness of the developed method. It is indicated that for the correct formation of the geometric model, data from multispiral computed tomography with angiography of the patient after CEE with a layer thickness of 0.6 mm and a current of 355 mA are required. To build a flow model, data of color duplex scanning in three sections are required: 1. In the proximal section of the common carotid artery (3 cm proximal to the bifurcation); 2. In the section of the external carotid artery, 2 cm distal to the carotid sinus; 3. In the section of the internal carotid artery, 2 cm distal to the carotid sinus. The result of computer calculations using specialized software (Sim Vascular, Python, Open Foam) is a mathematical model of blood flow in a vessel. It is an array of calculated data describing the speed and other characteristics of the flow at each point of the artery. Based on the analysis of RRT and TAWSS indicators, a computer model of bifurcation is formed, which makes it possible to predict areas of increased risk of restenosis development. Thus, the developed technique is able to identify a cohort of patients after CEE, subjected to a high probability of loss of the vessel lumen. Such an opportunity will provide a more precise supervision of these patients in the postoperative period with the aim of early diagnosis of restenosis and timely prevention of the development of adverse cardiovascular events.
Isolated Pancreatic Injury Diagnosed Seven Months After Thoracoabdominal Trauma
Authors: Inozemtsev E. O. , Grigoryev E. G. , Panasyuk A. I. , Kondrat’ev S. A.
Published: August 2021

We present a case of a closed thoracoabdominal trauma with pancreatic rupture. Closed abdominal trauma is one of the main causes for urgent hospitalization and emergency surgery. Injury of pancreatic ductal system is noted for the most severe course because of complications caused by outflow of the pancreatic juice into the retroperitoneal fat and the free abdominal cavity. One of the main factors affecting the efficacy of treatment is the time gap between a traumatic incident and hospitalization with subsequent surgical treatment. We report the results of management of a 53-year-old patient with closed thoracoabdominal injury and incomplete rupture of the pancreas, diagnosed 6 months after the “steering wheel” trauma. The injury was diagnosed with radiation techniques. Surgery included laparotomy, corporocaudal resection of the pancreas with splenectomy. The incidence of pancreatic traumatic injuries and the results of treatment are the matters for discussion.
OPINI GOING CONCERN: DITINJAU DARI AGENSI TEORI DAN PEMICUNYA
Authors: Endiana I Dewa Made , Suryandari Ni Nyoman Ayu
Published: August 2021

Kontinuitas perusahaan dapat diidentifikasi dari laporan keuangannya yang dikeluarkan oleh auditor. Kemampuan perusahaan dalam menyelesaikan kewajibannya merupakan hal yang diperhatikan oleh perusahaan untuk mempertahankan eksistensinya dalam persaingan yang ketat ini. Oleh karena itu, penelitian ini memiliki tujuan untuk mengetahui pengaruh pada ukuran perusahaan, perkembangan perusahaan, rasio hutang terhadap ekuitas, kualitas audit, opini audit tahun sebelumnya pada kecenderungan penerimaan opini audit going concern di perusahaan manufaktur yang terdaftar di Indonesia Bursa Efek. Menggunakan populasi data dari 165 perusahaan manufaktur terdaftar di Bursa Efek Indonesia dari 2016 hingga 2018, menggunakan teknik analisis data purposive sampling, menghasilkan 68 unit perusahaan manufaktur sebagai sampel penelitian per tahun dan menjadi 240 sampel penelitian selama 3 tahun. Metode Analisis Data yang digunakan adalah Analisis Regresi Logistik. Dari hasil uji hipotesis diperoleh hasil bahwa ukuran perusahaan, perkembangan perusahaan, rasio hutang terhadap modal, kualitas audit, dan opini audit periode sebelumnya tidak mempengaruhi kecenderungan opini audit going concern.
DETERMINANTS OF BANKING INDUSTRY PROFITABILITY: AN EMPIRICAL RESEARCH OF INDONESIA FINANCIAL INSTITUTIONS
Authors: Johan Suwinto
Published: August 2021

ABSTRAK
 
Penelitian ini bertujuan untuk mempelajari determinan profitabilitas perbankan di Indonesia. Penelitian difokuskan pada 19 bank yang dikategorikan sebagai bank book 3 dan 4 sesuai ketentuan bank sentral. Tujuh rasio keuangan utama, yaitu dampak pemegang saham (bank swasta versus bank milik negara), dan status dampak bank (bank milik lokal versus bank milik asing) dianalisis sebagai penentu profitabilitas bank. Kami menggunakan data panel seimbang dan menguji statistik model dengan pooled least square, model efek tetap, atau model efek acak dengan menggunakan program E-views. Sampelnya adalah 19 bank yang mempublikasikan laporan tahunannya dari tahun 2016-2018. Hasil empiris menunjukkan bahwa determinan utama profitabilitas perbankan adalah kredit macet. Pinjaman bermasalah yang lebih tinggi akan membutuhkan persyaratan cadangan yang lebih tinggi. Persyaratan cadangan yang lebih tinggi akan berdampak pada profitabilitas bank. Selain itu, penentu utama pengembalian ekuitas adalah status kepemilikan bank (kepemilikan lokal versus kepemilikan asing). Pemegang saham lokal menunjukkan lebih banyak dukungan untuk profitabilitas perbankan daripada pemegang saham asing. Variabel signifikan kurang dari 1%, dan hanya status pengaruh bank terhadap return on equity yang signifikan pada kurang dari 10%.
Development of Teaching Materials in the Form of Textbooks with Contextual Nuances Equipped with Mind Map on Material of Life Organization for Junior High School Students
Authors: Melta Defrian , D Rahmawati , Sumarmin Ramadhan
Published: August 2021

The purposes of this research are to develop and identify the validity and practicality of pocket book with contextual nuance on organization of life material for Junior High School students. This research used 3 steps of 4D Models, those are define, design, and develop. The subjects of this research were 5 validators, 2 teachers, and 20 students class VII from Junior High School Number 16, Padang. Data in this research was primary data collected from validity and practicality questionnaire. The result of validity was 86,69% in valid criteria, practicality by teachers was 88,87% in practice criteria, and practicality by students was 87,48% in practice criteria.
Relationship of Multiple Intelligence with Cognitive Learning Outcomes of Students in Class VIII Science Subjects of SMP 13 Padang
Authors: Saldayu Fazli , Ristiono Ristiono , Yogica Relsas , Sumarmin Ramadhan
Published: August 2021

ABSTRACT Intelligence is an ability, with its completeness process, which is capable of handling various problems. Each student has a tendency for intelligence from nine intelligences, namely Linguistic, Mathematical-Logical, Visual-Spatial, Intrapersonal, Naturalist, and Existential. This intelligence is called Multiple Intelligence. This research is a descriptive study, using a correlational study approach between multiple intelligences and student learning outcomes. To find out the relationship between variables, a correlation test was used using the Spearman-Rank correlation. The data obtained were analyzed by normality test. The results obtained in the form of population data are normally distributed. Furthermore, the data analyzed using correlation analysis with the results in the form of correlation variables that have no effect. Based on the results of the study in general it can be concluded that the intelligence of multiple intelligence has a significantly different relationship to learning outcomes. Although with a significantly different level of correlation, but multiple intelligence still has a relationship with learning outcomes, the point is that if the correlation coefficient increases, the learning outcomes of students will be more dominant. The coefficient of determination is 24.85% and 7.99% shows that learning outcomes in science subjects in class VIII 4 and class VIII 5 are influenced by multiple intelligences.Keywords: multiple intelligence, cognitive learning outcomes
The Development of Handout Images and Map of Concept In Material Classification of Living Things for Student of Class VII Junior High School 23 Padang
Authors: Mecita Viola , Yogica Relsas , Ristiono Ristiono , Fifendy Mades
Published: August 2021

Learning media is one of the determinants of success in the learning process in school. The use of learning media will greatly help the effectiveness of the learning process and add one of the teaching materials that can be used by students in learning. But the role of learning media will not be seen if its use is not in accordance with the learning objectives that have been formulated. Students find it difficult to connect the concepts contained in the material, then students find it difficult to understand the material concepts. The material on biology teaching materials used is like narration, language that is difficult to understand, and the appearance is less attractive. To overcome this problem, the teacher needs to develop teaching materials that are expected to be interesting and easy to understand by students in understanding the concepts contained in biology learning material. Teaching materials developed are Handouts. This research is Development Research conducted at FMIPA UNP and Padang Junior High School 23, using the Plomp development model (2013). The subject of this study consisted of 2 lecturers of Biology Department FMIPA UNP, 1 Biology teacher at SMP 23 Padang, and 29 students in grade VII of SMP 23 Padang. The data in this study are data obtained from the validity test questionnaire and practicality test. This data includes primary data, namely data obtained directly from the research subject.From the research, produced a nuanced handout of drawings and concept maps of living class classification material for class VII students of SMP which were categorized as valid with a value of 4.50, stated to be very practical with a value of 4.60 by the teacher and very practical with a value of 4.40 by participants student.
The Influence of The Power of Two Learning Model Containing Science Literacy on Students Learning Competencies in the Material of Human Digestive Systems in SMP Negeri 18 Padang
Authors: Yulianti Sari , Chatri Moralita , Yogica Relsas , Syamsurizal Syamsurizal
Published: August 2021

ABSTRACTThis research is based on the problems that exist in SMPN 18 Padang, students learning competencies are still low. Efforts that can be made are applying the learning model Power of Two with scientific literacy on digestive system material at SMPN 18 Padang. The purpose of this study was to determine the increase in the competency of students through the model The power of twowith scientific literacy in the material of human digestive systems in SMPN 18 Padang.This type of research is experimental research with a randomized control group posttest only design. The population in this study were all class VIII SMPN 18 Padang registered in the 2018/2019. Sampling was done using technique Simple Random Sampling, which was chosen as the sample of the study was class VIII.6 as the experimental and  VIII.7 as the control class. The instruments used were in the form of questions posttest for knowledge competencies, observation sheets for attitude and skills. The hypothesis was tested using the t-test, can be concluded that the competence of learners knowledge tcount 5,72> ttable 1.67, the competence of attitude  value tcount 1,84> ttable 1,67, and the competency of skills value tcount 3.39> ttable 1.67. This shows that the hypothesis is accepted. Concluded that the application of model The power of two with scientific literacy can improve the competency of knowledge, attitudes, and skills of class VIII students of SMPN 18 Padang. Keywords: the power of two,  scientific literacy, learning competency