bluuebunny/crossref_metadata_2025 huggingface dataset:
Real-time power inspection method based on multi-attention and strong semantic feature extractor
Authors: Zhao Qian , Ji Tangyu , Liang Shuang , Yu Wentao , Yan Chao
Published: May 2023

This paper proposed a multi-objective power inspection method based on multiple attention mechanisms and strong semantic feature extraction.Based on the Deeplabv3+ network model,the CBAM attention mechanism is introduced into the MobileNetV2 network to enchance the contextual information interaction capability; the ASPPAttention fast feature fusion structure is proposed to achievefast extraction of multi-dimensional valid information by designing deep separa-ble convolutions with different perceptual fields, and to enhance the pixel-levelfeature encoding capability with the CA attention mechanism; the lightweightfeature encoding capability is proposed. The proposed lightweight inverted con-volutional decoder structure improves the feature extraction capability of themodel by designing an inverted bottleneck convolutional structure in two quadru-ple downsampling layers with a low number of parameters, and introduces the CAattention mechanism to avoid the heterogeneous gap; in the training process, theconvergence speed of the model is accelerated by using migration learning, andDice Loss is introduced to avoid the effect of the number of samples on the gener-alization of the model. The experimental results show that the MIoU of the powersegmentation inspection method based on attention and information decouplingcan reach 48.5%, the accuracy rate can reach 97.5%, and the detection speed ofthe model can reach 40.8 FPS, which is a better balance of speed and accuracycompared with the network models of HRNet, PSPNet and DeeplabV3+.
Fabrication of g-C 3 N 4 @porphyrin nanorods hybrid material via CTAB surfactant-assisted self-assembly for photocatalytic degradation of Cr(VI) and methylene blue
Authors: Ho Quang Dinh , Le Tam The , Nguyen Giang T. , Nguyen Du Hoa , Nguyen Hao Hoang , Le Hiep Thu Thi , Chu Lam Thanh T. , Tran Chinh , Nguyen Phuong T. Hoai , Um Myoung-Jin , Nguyen T. Tung , Nguyen D. Duc , La Duong D.
Published: May 2023

Photocatalysts are an attractive solution for pollutant degradation under sunlight irradiation. One approach that has been proposed to enhance their activity is to combine two semiconductors, which can broaden the photon energy harvesting regions and improve charge separation. Herein, a facile approach to fabricating a g-C3N4@porphyrin nanorods hybrid material is presented using CTAB surfactant-assisted self-assembly of monomeric porphyrin molecules and g-C3N4 nanomaterials. The hybrid material was characterized using various technical methods, revealing a uniform distribution of porphyrin nanorods on the surface of g-C3N4. The photocatalytic performance of the hybrid material was evaluated by investigating its behavior for the photo -oxidation and -degradation of Cr6+ ions and methylene blue organic dye under simulated sunlight irradiation. High photocatalytic performance towards these two pollutants was exhibited by the hybrid material with a removal percentage of nearly 100% after 100 min of reaction time under the simulated sunlight spectrum. Furthermore, a potential photocatalytic mechanism of the C3N4@porphyrin nanorods photocatalyst was proposed, which involved the efficient separation and transfer of photo-induced electrons and holes on the surface of the hybrid material. An effective and facile method for developing high-performance photocatalysts is offered by this work, and advances in our understanding of their photocatalytic mechanisms have been made. The findings have important implications for wastewater treatment and solar energy conversion. The use of this hybrid material may contribute to addressing environmental challenges and assist in building sustainable energy systems.
The assessment of the dietary patterns of patients with Crohn’s disease (CD) in remission in Sri Lanka; an outpatient clinic based study
Authors: G Samarasekera T , R Jayatissa , N Fernandopulle , E Gunaratne I , T Harishchandra H D , L Samarasekera G B , Husseinpour Haneigh , Nishad Nilanga
Published: May 2023

Background/Aims: Diet is partly responsible for the exacerbation of symptoms in CD. The assessment of nutritional status and dietary pattern is crucial in CD. Study was designed to describe the dietary patterns of CD patients in remission attending to the gastroenterology clinic in National hospital of Sri Lanka
Methods: A descriptive cross-sectional study was carried out. Demographic, clinical and biochemical data and data on dietary patterns and behaviors were gathered using an interviewer administered questionnaire. Dietary intake was assessed using 24 hour dietary along with a 3 day diet diary. Data were analyzed using Statistical Package for Social Sciences 23.0.
Results: Overall, 50 adult patients including 32 males and 18 females diagnosed with CD were recruited. Mean age (s.d.) of the participants was 39.9 (8.4) years. Forty six percent of the population (n=23) was in normal BMI range while 36% was underweight and 18% was overweight. Majority (49, 98%) were non- vegetarians. Forty nine (98%) patients believed that certain food items worsen their symptoms of CD. The most commonly self-identified dietary triggers for CD relapse were carbonated drinks and red meat. Red meat (86%), Samposha (82%) and peanuts (70%) were identified as the mostly avoided food items. Own experience was the most influential source to prevent relapse (n=45, 90%) followed by medical advice (76%), social media and internet (50%) and family and friends (16%).
Conclusions: Assessment of nutrition status and dietary intake is crucial to optimize dietary intervention with targeted nutrition counseling, to enhance nutritional status in CD patients.
Magnetic flux response of non-Hermitian topological phases
Authors: Denner Marco Michael , Schindler Frank
Published: May 2023

We derive the response of non-Hermitian topological phases with intrinsic point gap topology to localized magnetic flux insertions. In two spatial dimensions, we identify the necessary and sufficient conditions for a flux skin effect that localizes an extensive number of in-gap modes at a flux core. In three dimensions, we furthermore establish the existence of: a flux spectral jump, where flux tube insertion fills up the entire point gap only at a single parallel crystal momentum; a higher-order flux skin effect, which occurs at the ends of flux tubes in presence of pseudo-inversion symmetry; and a flux Majorana mode that represents a spectrally isolated mid-gap state in the complex energy plane. We uniquely associate each non-Hermitian symmetry class with intrinsic point gap topology with one of these cases or a trivial flux response, and discuss possible experimental realizations.
Marginal quenches and drives in Tomonaga-Luttinger liquids
Authors: Datta Shouvik , Lapierre Bastien , Moosavi Per , Tiwari Apoorv
Published: May 2023

We study Tomonaga-Luttinger liquids thrown out of equilibrium by marginal deformations in the form of interaction modulations. This is modeled by quenching or periodically driving the Luttinger parameter or, equivalently, the compactification radius of the free boson conformal field theory between two different values. We obtain exact analytical results for the evolution of the Loschmidt echo and observables such as the particle and energy densities. Starting from generic initial states, the quench dynamics are shown to exhibit revivals and temporal orthogonalities. For the periodic drive, we show stability or instability of time-evolved physical quantities dependent on the drive parameters. We also compare the corresponding marginally deformed thermal density matrices by non-perturbatively evaluating their Rényi divergence as a Euclidean quench. All the dynamics are shown to be crucially dependent on the ratio of the Luttinger parameters, which corresponds to the Zamolodchikov distance in the space of marginal deformations. Our setup is equivalently interpreted as the dynamics of the bosonic string upon instantaneous changes of the target-space radius.
Grammarly as Automated Writing Evaluation: Its Effectiveness from EFL Students’ Perceptions
Authors: Dewi Utami
Published: May 2023

The research aimed to describe EFL students’ perceptions of the effectiveness of Grammarly as an Automated Writing Evaluation (AWE). Nowadays, the Grammarly application is used to give AWE in many EFL writing classes. The respondents of the research were 75 students in an EFL writing class. The questionnaires and interviews were used to explore the students’ perceptions of using Grammarly in editing their drafts. The data from the questionnaires were calculated by percentages, and the data from the interview were analyzed by content analysis. The results show that the students have positive perceptions of using the Grammarly application as AWE. They state many advantages of Grammarly, such as Grammarly helps to identify errors in grammar, punctuation, spelling, and word choices in writing; helps to minimize errors in writing products; to enhance paraphrasing skills; to corrects the errors in writing anytime and anywhere; helps to improve students’ vocabulary; and Grammarly is easier to find errors in writing. Besides the advantages, the students state the drawback of Grammarly as AWE, such as Grammarly for free version has limited features to check errors; Grammarly for the premium version is expensive for students; and Grammarly cannot be accessed offline. The results of the questionnaires and interview represent that the Grammarly application has positive impacts on EFL students as an automated writing evaluation.
Hot-Fit Model to Measure the Effectiveness and Efficiency of Information System in Public Sector
Authors: Sala Elvira Esperanza , Subriadi Apol Pribadi
Published: May 2023

The research aimed to determine the effectiveness and efficiency of the information systems’ implementation. The research used the modified Human Organization Technology-Fit (HOT-Fit) as the model to measure information systems’ effectiveness and efficiency. Each indicator of the HOT-Fit model is mapped into two categories, namely effectiveness and efficiency. Data collection was conducted through interviews with the users of population administration information system (SIAK), and observation of activities at the public office. The data were analyzed qualitatively by assessing the achievement of each indicator of effectiveness and efficiency found in the interview and observation. It is found that effectiveness indicators are level of use, attitude, perceived usefulness, communication, availability, security, completeness, accuracy, timeliness, empathy, and transparency. Meanwhile, indicators to measure efficiency are users, training, staff support, ease of use, ease of learning, response time, access to technical support, and quick responsiveness. The research also expands the scope of the HOT-Fit model in evaluating information systems. Practically, the research can be a reference for evaluating the effectiveness and efficiency of information system implementation in the public sector. It also can be used to improve the achievement of indicators that have not achieved maximum results to improve services to the community.
Evaluating the Effects of Entrepreneurial Orientation and Managerial Skills on Small and Medium Enterprises Performance in Lagos State
Authors: Alaka Nureni Sanusi , Okogua Obasuyi
Published: May 2023

The aim of the research was to examine the influence of entrepreneurial orientation and management skills on the performance of Small and Medium Enterprises (SMEs) in the state of Lagos, Nigeria. Quantitative survey research design was adopted, and multiple regression method of analysis was employed for the research. The population was 11.663 registered SMEs in Lagos State. Cochran's sample sizing was used to determine the sample size of 500. From the total of 500 questionnaires distributed, 473 were completed and returned, which corresponded to a response rate of 96,6%. The data collected were analyzed using both descriptive and inferential statistics. The results shows that entrepreneurial orientation practices have a positive and significant effect on profitability (β = 0,110, t = 1,904, p<0,05). However, management skills have a positive but not significant influence on the profitability of the selected SMEs (β = 0,030, t = 0,532, p>0,05). The research recommends that operators in this economic sector should look deeply at the variables of the research as essentials for improving business performance. It also put forward that Small and Medium business owners or managers should not be afraid of taking calculated risks as this would ensure their profitability.
Sass Gábor munkássága. Egy gazdasági géptan tankönyv születéstörténete
Authors: Albert Gábor
Published: May 2023

Írásunk a gépészmérnök Sass Gábor tankönyvírói munkásságát és Gazdasági géptan tankönyvét veszi górcső alá. Kiemelten támaszkodunk a szerző irathagyatékára, mely a Magyar Mezőgazdasági Múzeum és Könyvtár Agrártörténeti Iratok Gyűjteményének értékes darabja. Az iratcsomó a tankönyvről készült bírálati jelentéseket, a szerzői választ, a szerzőnek a mezőgazdasági gépgyárakkal folytatott levelezéseit, valamint a szerzőtárssal, Molnár Bélával folytatott 1935-ös és 1936-os levélváltásait is őrzi. A tankönyv tényleges iskolai használatára vonatkozó adatokat a korabeli iskolai értesítőkből gyűjtöttük ki. Sass életrajzához irathagyatéka mellett Réz Gyula 1989-es írását, géptörténeti ismereteink kiegészítéséhez Estók János 2001-es kötetét hívtuk segítségül. Kutatásunk interdiszciplináris kötöttségű, hiszen az iskolatörténeti és tankönyvtörténeti kutatások mellett az agrártörténeti, agrár szakoktatástörténeti, továbbá géptörténeti- és gépgyártástörténeti ismereteinket egyaránt gazdagítja
Technology for adaptation: a case study of developing a detailed inventory of drinking water supply technologies along the salinity-affected coastal region of Bangladesh
Authors: Islam Md. Sirajul , Deb Biplob Kumer , Alam Shoeb Reaz , Nishat Ainun
Published: May 2023

The south-western coastal zone of Bangladesh is suffering from an acute crisis of freshwater due to salinity intrusion. First, the extent of the problem and its causes in detail were investigated. Climate change along with a few other anthropogenic impacts are the main causes. Exploring technologies for adaptation to climate change is emphasized today to overcome the problem of climate change impact. The coastal community was found to be already adopting technological measures as an adaptation means. This study developed a detailed inventory of all the available indigenous water supply technology options along the region and categorized them. An analysis of the suitability of the technologies was done, focusing on factors like the state of the technology, convenience in operation, quantity and quality of the supplied water, as well as financial viability or management practice. Both qualitative and quantitative approaches to the study were adopted to collect and analyze the data through extensive field visits, laboratory testing, and secondary data analysis. It is found that in most cases, solutions are on an ad hoc basis, having a lifetime of less than 5 years. In some places, people are gradually moving towards community-based and long-term hi-tech solutions.
Parameters and methods used in flood susceptibility mapping: a review
Authors: Kaya Cagla Melisa , Derin Leyla
Published: May 2023

A correct understanding of the parameters and methods used in flood susceptibility mapping (FSM) is critical for identifying the strengths and limitations of different mapping approaches, as well as for developing methodologies. In this study, we examined scientific publications in the literature using WoS. Although the number of methods used is quite high, the number of parameters used in these methods varies, with a maximum of 21 and a minimum of 5 parameters preferred. It was found that the most commonly used parameter has a preference rate of 97%, but there is no common parameter in 100% of the studies. The methods used for determining flood susceptibility include multi-criteria decision-making (MCDM) methods, physically based hydrological models, statistical methods, and various soft computing methods. Although the use of traditional statistical methods and MCDM methods is already high among researchers, the methods used in flood susceptibility analysis have evolved over the years from traditional human judgments to statistical methods based on big data and machine learning. In the reviewed studies, it was observed that machine learning, fuzzy logic, metaheuristic optimization algorithms, and heuristic search algorithms, which are soft computing methods, have been widely used in FSM in recent years.
Temporal evaluation of surface water quality in semiarid regions: a case study of the Ouled Mellouk dam in north-western Algeria
Authors: Madene Elaid , Boufekane Abdelmadjid , Busico Gianluigi , Meddi Mohamed , Maizi Djamel
Published: May 2023

This work aimed at evaluating the impact of human activity and geology on the surface water quality of the Ouled Mellouk dam (northwestern Algeria). Specifically, methodology aims to assess seasonal variations of several parameters (EC, TDS, pH, SO42−, Cl−, Ca2+, Na+, HCO3−, NO3−, PO43− and Mg2+, organic matter, suspended solids, BOD5, COD) from 2007 to 2013 to define the processes controlling the mineralization and pollution of the surface water. The results show high salinization recorded during the periods of heavy precipitation or flooding, due to leaching of dolomitic limestones and evaporitic deposits from the saliferous formations of the surrounding mountains. High concentrations of NO3−, NO2−, NH4+, and organic matter can instead be attributed to the use of fertilizers in agriculture. Moreover, the PCA application shows that salinization (49.92%), anthropogenic pollution (19.38%) and agricultural pollution (12%) are the most significant degradation factors, respectively. The saturation index of carbonates and gypsiferous minerals shows the carbonates precipitate before the gypsiferous minerals, which allowed the chemical elements coming from the dissolution of gypsum and halite to acquire significant contents. In addition, the evolution of biological oxygen demand and organic pollution shows slight pollution of the dam water.
Depósitos Cromitíferos do Vale Jacurici: Uma Revisão Bibliográfica
Authors: Rebouças Iago Silva , Roberto Bacelar Hühn Sérgio , De Paula Miranda Mateus , Ângelo da Silva Neto Cláudio , Shantala Fernandes de Oliveira Sousa Joyce , Daniel da Silva Silveira Antonio
Published: May 2023

Por muitos anos, a cromita foi bastante utilizada na indústria como componente para produção de pigmentos para tintas. Os principais depósitos minerais de cromita são encontrados na África do Sul, Cazaquistão e Índia (90% das reservas). O Brasil detém 0,13% das reservas mundiais de depósito de cromo. Os maiores exemplares em território nacional são encontrados no complexo máfico-ultramáfico do Vale do Jacurici-BA. Embora exista alguns trabalhos com finalidade da caracterização geológica do Vale do Jacurici e do segmento Ipueira-Medrado, é identificado uma baixa produção científica em outros ramos das geociências. O objetivo do trabalho é o desenvolvimento da primeira revisão bibliográfica sistemática dos depósitos cromitíferos nestas regiões. Este trabalho promoverá uma base de informações que contribuirão com o direcionamento de futuras linhas pesquisas na área. As pesquisas bibliográficas foram desenvolvidas de modo sistemático, onde os trabalhos usados como base foram obtidas na plataforma digital Google Acadêmico: 24 artigos aplicáveis à temática em questão, 03 livros, 03 relatórios e um resumo expandido. O desenvolvimento de pesquisas focadas emramos mais específicos em geociências, auxiliariam na caracterização mais ampla em torno do minério de cromo da região. Sendo assim existem estudos ainda não explorados que abrirão novos horizontes para a pesquisa mineral.
Current Formulation Strategies to Design Novel Carriers for Targeted Drug Delivery and Management of Infectious Keratitis: A Comprehensive Review on the Present State of the Art
Authors: Sarkar Tumpa , Singh Mohini , Jana Bani Kumar , Mazumder Bhaskar
Published: May 2023

Objective:

Infectious keratitis is a pernicious disease that affects the anterior segment of the
eye and is one the leading causes of blindness worldwide. This disease may cause severe visual impairment
or permanent vision damage if left untreated.

Discussion:

No doubt there are many conventional drug delivery systems to treat ocular keratitis, yet it is
the fifth leading cause of blindness globally. This is the result of the eye's complex anatomy and barrier
system, which restricts the total ocular contact time of the conventional formulations resulting in underdosing.
The widely used traditional formulations to treat keratitis, like antibiotic eye drops and ointments,
are rendered useless due to less ocular contact time and low therapeutic drug levels at the target ocular
site. The main requirement of the present time is to develop novel drug delivery-backed stratagems to
overcome the shortcomings of conventional formulations, which will reduce the morbidity associated
with infectious keratitis and improve clinical outcomes. It is worth mentioning that there are documented
incidents of Herpetic keratitis of the cornea followed by COVID-19 infection and vaccination.

Conclusion:

This paper is a rigorous review of all the novel drug delivery strategies to combat ocular
keratitis. These future drug delivery strategies will pave the way for the present time researcher and formulation
chemists to develop multi-dimensional novel formulations that are safe, patient-compliant, and
surpass the ocular barriers to maintain therapeutic drug levels in ocular tissues.
Relationship between Subclinical Hypothyroidism and Uremic Pruritis in
Hemodialysis Patients
Authors: Kotb Essam , Mohamed El mancy Ismail , Ghounim Ramadan  Mohamed Ibrahim , Ahmed  Ayoub Hazem Sayed , Rashed AL-Sayed M. , EL-Nasser Waleed S. , Ismail  Hamed Hani , Aladl Aladl Hossam , Sabrh Mostafa , Eliwa Ahmed , Ghamry Esam M. , Abdelhamed Mohamed R. , Mahmoud Tamer M.
Published: May 2023

Background and Aim:

Uremic pruritus (UP) is one of the most distressing symptoms in hemodialysis (HD) patients. Subclinical hypothyroidism (SCH) is a biochemical condition with high prevalence in HD patients. The present multicentric study aimed to assess the relationship between UP and SCH in HD patients.

Methods:

The present cross-sectional study included 328 HD patients. All patients were submitted to careful history through clinical examination and standard laboratory assessment. Pruritis was evaluated using the pruritis visual analog scale (VAS). Patients were diagnosed with SCH if they had TSH levels above the upper limit of the normal reference range in association with normal free thyroxine (FT4) levels.

Results:

Among the studied patients, there were 196 patients (59.8 %) with UP. Comparison be-tween patients with UP and patients without revealed that patients in the former group had signifi-cantly longer HD duration (median (IQR): 47.5 (27.0-72.5) versus 36.0 (23.0-50.5) months, p  0.001) and lower Kt/v (median (IQR): 1.4 (1.09-1.7) versus 1.54 (1.12-1.91), p = 0.009). Moreover, they had significantly higher ferritin (median (IQR): 653.0 (526.0-800.0) versus 628.0 (470.8-716.0) ng/mL), hsCRP (median (IQR): 12.0 (8.0-14.0) versus 8.0 (6.0-9.0) mg/dL, p  0.001) and TSH levels (median (IQR): 4.34 (1.98-5.2) versus 3.34 (1.9-4.85) μIU/ml) with a significantly higher frequency of SCH (45.9 % versus 28.8 %, p = 0.002). Logistic regression analysis identified hemodialysis duration (OR (95%) CI): 1.02 (1.009-1.028), p  0.001), ferritin levels (OR (95% CI): 1.002 (1.001-1.003), p  0.001), and SCH (OR (95% CI): 0.54 (0.32-0.89), p = 0.016) as significant predictors of UP.

Conclusion:

The present study suggested a possible link between SCH and the development of UP in HD patients.
Nursing Research Priorities based on the Nurse-sensitive Indicators: Scoping Review
Authors: Hakami Afaf , Hussain Fazal , Bakheet Anas , Alghamdi Khalid , AlAtrash Khalid
Published: May 2023

Background:

Patient-centeredness, safety, and quality of care are major healthcare concerns worldwide. Clinical indicators are essential for monitoring and evaluating safety and quality of care within the health care system. Therefore, research on clinical indicators can improve the quality of care, promote good practices, clarify key concepts, and identify gaps vital to nursing care.

Objective:

The study aims to explore nurse-sensitive indicators to find significant research areas and prioritize them.

Design:

The study design is exploratory research conducted through scoping review, followed by Delphi consultation to identify nurse-sensitive indicators applicable in the Saudi Arabia health care system and prioritize these indicators as research areas.

Results:

The most frequently cited indicators are patient fall, medication error, patient satisfaction, catheter-associated infection, pain, pressure ulcer, the incidence of deep vein thrombosis or pulmonary embolism, appropriate levels of nursing skill mix, and nursing initial and need assessment. The result shows that (33) NSIs are essential to the quality of nursing care and patient safety in Saudi Arabia.

Conclusion:

Patient-centeredness, patient safety, a healthy work environment, and a nursing informatics system are significant research dimensions. We found that nurse satisfaction, patient satisfaction, pressure ulcers, patient falls, nurse-patient communication, patient engagement, and pain management are research priorities.

Recommendations:

Further studies must be conducted on NSIs that address patient-centeredness, safety, a healthy work environment, and a nursing informatics system. It can be observed that most of the studies focused on outcome indicators, and there is a need to study patient-reported indicators as a significant patient-centered concept.
The Cytoglobin Expression Under Hypoxic Conditions in Covid-19 Cases
Authors: Wulandari Endah , Hapsari Rr Ayu Fitri , Tjakradidjaja Francisca A , Alfiah   , Suri Auliyani Andam
Published: May 2023

Introduction:

Cytoglobin (Cygb) is an oxygen transporter marker that appears in hypoxic conditions. The clinical condition of Corona Virus Disease 2019 (COVID-19) cases, in general is that patients experience hypoxemia with low oxygen saturation. The Cygb gene is stimulated by the Hypoxia-Inducible Factor-1alpha (HIF-1α) transcription factor, which is stable in hypoxia.

Methods:

This study investigates Cygb expression in hypoxic COVID-19 cases. The design of this research is analytically observational. Parameters measured were Cygb mRNA and protein levels, correlation of HIF-1α and Cygb proteins in COVID-19 patients with Alpha, Beta, Delta, Omicron variants and negative control patients.

Results:

The results showed that each Cygb mRNA level decreased by 0.50, 0.92, 0.75 and 0.84 times that of the control. In contrast, Cygb protein levels (ng/mL) increased (16.95; 20.33; 21.20; 14.01 and 6.29 control). Strong negative correlation between mRNA and Cygb protein (R = -0.611). Strong positive correlation between HIF-1α and Cygb protein (R = 0.670).

Conclusion:

This study showed that Cygb mRNA expression decreased, further increasing Cygb protein; HIF-1α protein levels increased, further increasing Cygb protein. In COVID-19 patients (Alpha, Beta, Delta and Omicron variants), there is an increase in Cygb protein levels through stimulation of HIF-1α, which is stable under hypoxic conditions. The regulation of Cygb in this study has the potential to become the basis for handling cases of viral infections or other cases of hypoxia.
Validation of the Ukrainian and Russian versions of the KPPS
Authors: Khubetova I.V. , Slobodin T.M. , Pavlyshyna N.M. , Kripchak O.O. , Vorokhta Yu.M.
Published: May 2023

Background. The purpose of the study is to validate the Ukrainian and Russian versions of the King’s Parkinson’s disease Pain Scale (KPPS). Materials and methods. The study was conducted at the Odesa Regional Clinical Hospital in 2018–2020. We examined 160 patients with Parkinson’s disease verified by the Parkinson’s UK Brain Bank criteria (main group) and 100 people of the same age without signs of extrapyramidal pathology (controls). All patients were examined in accordance with the requirements of current clinical protocols. Additionally, all study participants answered the questions of the KPPS provided in the Ukrainian or Russian version. Mann-Whitney method with Benjamini-Hochberg correction was used for multiple comparisons. Results. Pain of varying severity was detected in 121 of 160 (75.6 %) patients with PD. There were no cases of pain in the control group. The most common was nocturnal (52.5 %) and musculoskeletal pain, both isolated (23.1 %) and in various combinations (up to 65.6 %). Pain associated with motor fluctuations occurred in 27 (5.1 %) cases. Central chronic pain was detected in 22 (13.8 %) patients, visceral chronic pain — in 11 (6.9 %). Orofacial pain was noted in 19 (11.9%) cases. Pain associated with edema and signs of inflammation was found in 24 (15.0 %), radicular pain — in 17 (10.6%) people. Cronbach’s alpha for all domains of the scale was higher than 0.7. Pain severity by the visual analogue scale correlated with the KPSS score (r = 0.53). Conclusions. The study data indicated the acceptable validity of the Ukrainian and Russian versions of the KPSS. The questionnaire can be recommended for widespread use in assessing the phenotype of pain and its severity in patients with Parkinson’s disease.
A Deep Learning Approach for Author Profiling using Word Embeddings
Authors: Reddy Dr. T. Raghunadha , Madhubala B. , Varshini G. , . Fayaz S. K
Published: May 2023

Abstract: The task of author profiling involves predicting various characteristics of an author based on their writing style, such as their age, gender, native language, and personality traits. The PAN2013 shared task focused on author profiling in social media, where participants were tasked with predicting the gender and age of Twitter users based on their tweets. In recent years, deep learning approaches have become popular for author profiling. Two popular models are GloVe and FastText are used by the researchers to generate word embeddings. GloVe is a word embedding model that represents words as vectors in a highdimensional space, while FastText takes into account subword information to represent words. Both models have been shown to be effective for various natural language processing tasks. For the PAN2013 task, participants used various deep learning models with GloVe and FastText embeddings to predict the age and gender of Twitter users. Some approaches used a combination of multiple models to improve the performance. In this article, we focused on improving the accuracy of age and gender classification on the PAN2013 dataset, which is a benchmark corpus for author profiling. We utilized deep learning models such as Long Short-Term Memory (LSTM) and Convolutional Neural Network (CNN) classifiers to classify authors based on their age and gender. We also used pre-trained word embeddings such as FastText and GloVe to represent the text data. Our results showed that the LSTM model achieved an accuracy of 57.53% for age classification and 60.48% gender classification, while the CNN model achieved an accuracy of 59.32% for age classification and 52.21% for gender classification. We observed that these models have been shown to be effective for various natural language processing tasks and can be used for other author profiling tasks as well.
Fostering Women Empowerment through Financial Inclusion in India
Authors: Kumari Manisha
Published: May 2023

Abstract: This study attempts to investigate how financial inclusion affects women's empowerment in India. The report offers a thorough analysis of India's current financial inclusion situation. It evaluates the success of the numerous measures made by the Indian government and the private sector to encourage financial inclusion and women's empowerment. The study also offers potential ways to address the barriers that women may face in gaining access to financial services. The report concludes with policy proposals for improving financial inclusion and advancing women's empowerment in India that are addressed to decision-makers, financial institutions, and other stakeholders. Overall, the study comes to the conclusion that financial inclusion might be extremely important for advancing women's empowerment and gender equality in India.
Elementos para una poética de la cárcel en el documental chileno contemporáneo
Authors: Corro Penjean Pablo
Published: May 2023

El artículo, que identifica y analiza estéticamente documentales chilenos recientes sobre cárceles, advierte el reemplazo descriptivo del mecanismo judicial, del procedimiento punitivo y la norma social alterna como tópicos convencionales de la prisión, mediante la revelación de facetas originales de la subjetividad encarcelada expresada por el protagonismo exacerbado de las palabras y los cuerpos de los presos. Para desconectar lo político de estos documentales del tópico de la dictadura el artículo somete su corpus de la prisión a la exégesis de diversas teorías filosóficas sobre la disciplina y la visibilidad como sentido espacial de lo contemporáneo.
Decentralised Deconfliction of Aerial Robots in High Intensity Traffic Structures
Authors: Crann Verdon , Amiri Peyman , Knox Samuel , Crowther William
Published: May 2023

Projections for future air mobility envisage intensely utilised airspace
that does not simply scale up from existing systems with centralised air
traffic control. This paper considers the implementation and test of a
software and hardware framework for decentralised control of aerial
vehicles within intensely used airspace. Up to 10 rotary wing vehicles
of maximum all up mass of 1 kg are flown in an outdoor volume
with length scale of 100 m with GPS and WiFi connectivity. Flight
control is implemented using a Pixhawk 4 flight controller running the
PX4 firmware with guidance algorithms run on a separate onboard
companion computer. Deconfliction is implemented using a simple elastic
repulsion model with a guidance update rate of 10 Hz. Traffic
structures are constructed from a path of directed waypoints and
associated cross sectional geometry. Junctions are implemented when two
paths converge into one or when one path diverges into two. Agents
engage with structures through execution of flow, merge and swirl
velocity rules. Calibration experiments showed that the worst case
latency in agents sharing position information was of the order of 0
.5 s made up from delays due to finite guidance update
rate, WiFi processing and centralised message processing. A choice of
vehicle cruise speed of 2 m/s and conflict radius of 2 .5
m provided an acceptable compromise between experiment time
efficiency (speed) and spatial efficiency (resolution) within the test
volume. Results from recirculating junction experiments show that peak
deconfliction activity occurs at the junction node, however biased
distribution of agents within a corridor means the peak intensity is
pushed ahead of the node. Use of meshed helical junction structures
significantly reduces the intensity of conflict at the expense of
reduced junction time efficiency.
Long-term efficacy and safety of dust mite subcutaneous immunotherapy in monosensitized and polysensitized children with allergic rhinitis
Authors: Xie Zhihai , Yuan Xuan , Xie Shaobing , Zhang Hua , Zhang Junyi , Fan Ruohao , Jiang Weihong
Published: May 2023

Objective: The long-term efficacy of single-allergen-specific
immunotherapy in polysensitized allergic rhinitis (AR) subjects remains
uncertain. This study aimed to evaluate the long-term efficacy and
safety of dust mite subcutaneous immunotherapy (SLIT) in monosensitized
and polysensitized children with AR. Methods: This prospective
study recruited 130 children with AR, divided into a monosensitization
group and a polysensitization group. Patients received standardized dust
mite SLIT for 3 years and were followed up for 5 years. Total nasal
symptom score (TNSS), symptom and medication score (SMS), visual
analogue scale (VAS) and rhinoconjunctivitis quality of life
questionnaire (RQLQ) were assessed and compared between the two groups
at T0 (before treatment), T1 (1 year of SLIT), T2 (2 years of SLIT), T3
(end of SLIT) and T5 (2 years after the end of SCIT). Safety was
assessed through adverse events (AEs). Results: 51
monosensitized and 50 polysensitized children completed this study. At
the end of SCIT, 47 monosensitized and 46 polysensitized children were
effectively treated, respectively, with no significant difference (P
> 0.05). TNSS, SMS, VAS and RQLQ were significantly lower
in T1, T2, T3 and T5 in the two groups compared with T0 (P <
0.05). The differences in TNSS, SMS, VAS and RQLQ between the two groups
were not statistically significant at T1, T2, T3 and T4 (P
> 0.05), while the differences were significant at T5 (P
< 0.05). No serious AEs were reported. Conclusion:
Standardized dust mite SCIT has similarly beneficial long-term efficacy
and safety in monosensitized and polysensitized children.
Monosensitization children appear to receive more durable benefits.
Blood+ proteomics reveals hemorrhagic shock mechanisms in a severe hemorrhagic shock rat model
Authors: Hao Shasha , Zheng Shifan , Li Wanjing , Xie Xintong , Li Shen , Zhang Honghui , Wang Hong , Zhou Wentao , Liu Jiaxin , Yang Chengmin
Published: May 2023

ABATRACT: Hemorrhagic shock is one of the most important complications
of war trauma and an important cause of early death from trauma, so
timely diagnosis and treatment are of overwhelming importance. A rat
model of 65% severe hemorrhagic shock was established to analyze the
different proteins in the plasma between normal rats and predict the
mechanism preliminarily by Blood+ proteomics. The results showed that a
total of 190 regulated proteins were detected in plasma in rats with
severe hemorrhagic shock compared to normal rats. Bioinformatics and
enrichment analysis of regulated proteins showed that they were widely
distributed in 45 signaling pathways. Of these, 25 of the 190 proteins
were enriched in the PI3K-Akt signaling pathway, indicating a strong
link between this pathway and severe ischemia. Other enrichment pathways
in this study include primary immunodeficiency (PID), toll-like receptor
signaling pathway, ECM-receptor interaction, all of which are closely
related to autoimmune disorders, inflammatory responses, and
anti-inflammatory responses. In conclusion, this study revealed an
overview of the framework of protein changes in the plasma of rats with
severe hemorrhagic shock, and preliminarily analyzed the mechanism of
initial response to severe ischemia.
Healthy aging and cognitive impairment alter EEG functional connectivity in distinct frequency bands
Authors: Kumar Wupadrasta , Ray Supratim
Published: May 2023

Functional connectivity (FC) indicates the interdependencies between
brain signals recorded from spatially distinct locations in different
frequency bands, which is modulated by cognitive tasks and is known to
change with aging and cognitive disorders. Recently, the power of
narrow-band gamma oscillations induced by visual gratings has been shown
to reduce with both healthy aging and in subjects with mild cognitive
impairment (MCI). However, the impact of aging/MCI on stimulus-induced
gamma FC has not been well studied. We recorded electroencephalogram
(EEG) from a large cohort (N=229) of elderly subjects (>49
years) while they viewed large cartesian gratings to induce gamma
oscillations and studied changes in alpha and gamma FC with healthy
aging (N=218) and MCI (N=11). Surprisingly, we found that aging and
disease changed power and FC in different ways. With healthy aging,
alpha power did not change but FC decreased significantly. MCI reduced
gamma but not alpha FC significantly compared with age and gender
matched controls, even when power was matched between the two groups.
Overall, our results show distinct effects of aging and disease on EEG
power and FC, suggesting different mechanisms and the potential to use
EEG stimulus-induced FC along with power for early diagnosis of
Alzheimer’s Disease.
Global asymptotical stability for a fishery model with seasonal harvesting
Authors: Chen Ying , Huang Lihong , wang jiafu
Published: May 2023

A new fishery model is proposed by using the strategy of seasonal
harvesting. Sufficient and necessary conditions are established to
ensure the existence of a unique equilibrium or a periodic solution by
the approach of Poincaré maps. It is shown that the equilibrium or the
periodic solution is globally asymptotically stable. Numerical examples
are provided to demonstrate the model dynamics and some biological
implications are given as well.
Automated benchmarking of combined protein structure and ligand conformation prediction
Authors: Robin Xavier , Leemann Michèle , Sagasta Ander , Eberhardt Jerome , Schwede Torsten , Durairaj Janani
Published: May 2023

The prediction of protein-ligand complexes (PLC), using both
experimental and predicted structures, is an active and important area
of research, underscored by the inclusion of the Protein-Ligand
Interaction category in the latest round of the Critical Assessment of
Protein Structure Prediction experiment CASP15. The prediction task in
CASP15 consisted of predicting both the 3-dimensional structure of the
receptor protein as well as the position and conformation of the ligand.
This paper addresses the challenges and proposed solutions for devising
automated benchmarking techniques for PLC prediction. The reliability of
experimentally solved PLC as ground truth reference structures is
assessed using various validation criteria. Similarity of PLC to
previously released complexes are employed to judge the novelty and
difficulty of a PLC as a prediction target. We show that the commonly
used PDBBind time-split test-set is inappropriate for comprehensive PLC
evaluation. Finally, we introduce a fully automated pipeline that
predicts PLC and evaluates the accuracy of the protein structure, ligand
pose, and protein-ligand interactions.
Trends in Time in Range–Related Publications and Clinical Trials: A Bibliometric Review
Authors: M. Patel Pranav , M. Abaniel Richard , Dogra Natasha , B. Lo Charles , A. Frazzitta Marie , S. Virdi Naunihal
Published: May 2023

  

Objective. The goal of this article was to describe trends in publications (including conference abstracts) and clinical trials that report on glycemic time in range (TIR).

Data sources. Reviewed databases included but were not limited to MEDLINE and Embase. Clinical trial registries were also sourced. 

Study selection. All studies reporting TIR published between 2010 and 2021 were included. Clinical trials reporting TIR that started in or after 2010 were also included. Non-English publications, abstracts, and clinical trials were excluded. Book chapters, nonhuman studies, and studies not reporting TIR were excluded.

Data extraction. Manuscript/abstract category, publication year, study region, interventional versus observational role of continuous glucose monitoring (CGM), and clinical trial start and completion dates were captured. Glycemic outcomes reported in publications or trials, including TIR as a primary outcome, A1C, time below range (TBR), and time above range (TAR), were also captured. 

Results. A total of 373 clinical trials, 531 publications, and 620 abstracts were included in the review. The number of trials, publications, and abstracts reporting TIR significantly increased, particularly between 2018 and 2021, during which time the number of clinical trials, publications, and conference abstracts reporting TIR increased by sixfold, 12-fold, and 4.5-fold, respectively. About 35–44% of studies reported TIR as a primary outcome. Approximately 54% of clinical trials, 47% of publications, and 47% of conference abstracts reported the role of CGM to be observational. TBR was reported more often than TAR.

Conclusion. The marked increase in the number of trials, publications, and abstracts reporting TIR highlights the increasing significance and acceptance of TIR as an outcome measure in diabetes management. 
Frequency and Correlates of Depression in Hemodialysis Patients versus Apparently Healthy Population in Egypt
Authors: Farouk Megahed Abir
Published: May 2023

Background: Depression is the most common mental health condition in the general population. Additionally, depression is common in hemodialysis patients and is associated with a lower quality of life. The social causes of depression have been ignored for a long time. We aimed to assess the severity and correlates of depression in HD patients and compare them to a group of apparently healthy individuals in Egypt. Methods and Subjects: The study was conducted in four dialysis units in Egypt where 234 patients and 242 healthy individuals were recruited. The depression scoring, demographic data, and associated comorbidities were recorded. Depression was measured using the Center for Epidemiologic Studies Depression Scale (CES-D), NIMH. The higher scores indicated the presence of more symptomatology. Results: The total studied groups were 234(136 males, 98 females) patients on dialysis with a mean age of 55.6±13.6 years (range 21–79 years), and 242(157 males, 85 females) healthy individuals with a mean age of 33.6±13.3 years (range 18–70 years). Females both in dialysis patients as well as in the controls had statistically significantly higher depression scores indicating more depressive symptoms, than their male counterparts. Depression scores were significantly negatively correlated with the ages of control individuals, while they had non-significant positive correlations with ages and BMIs in cases. More depressive symptoms were associated with better socioeconomic status and higher education in the control group, although depressive symptoms increased with lower socioeconomic status and lower level of education in HD patients. In HD patients, the severity of depressive symptoms was significantly related to the presence of diabetes mellitus and ischemic heart disease. On the other hand, the more depressive symptoms in HD patients without associated comorbidities were not statistically significantly different from that in the apparently healthy group. Conclusion: The severity of depressive symptoms was different demographically between hemodialysis patients and the apparently healthy individuals, and was more pronounced in patients with more advanced age, lower socioeconomic status, and lower education, necessitating more consideration of social and psychological care for these patients.
MERDEKA BELAJAR DALAM PANDANGAN KI HADJAR DEWANTARA DAN RELEVANSINYA BAGI PENGEMBANAGAN PENDIDIKAN KARAKTER
Authors: Ainia Dela Khoirul
Published: May 2023

Merdeka belajar atau kebebasan berpikir merupakan gagasan yang dicetuskan oleh Menteri Pendidikan dan Kebudayaan Republik Indonesia. Tujuan dari merdeka belajar yaitu menciptakan pendidikan yang menyenangkan bagi siswa dan guru, karena selama ini sistem pendidikan di indonesia masih memiliki permasalahan yang kompleks. Selama ini pendidikan lebih menekankan pada aspek pengetahuan daripada aspek keterampilan. Dengan dicetuskannya gagasan merdeka belajar siswa dan guru dibebaskan dalam mengembangkan bakat dan ketrampilan dalam dirinya. Merdeka belajar menekankan juga pada aspek pengembangan karakter yang sesuai dengan nilai-nilai bangsa indonesia. Ki Hadjar Dewantara memandang pendidikan sebagai pendorong bagi perkembangan siswa yaitu pendidikan mengajarkan untuk mencapai perubahan dan kebermanfaatan bagi lingkungan sekitar. Merdeka belajar yang digagas oleh Menteri Pendidikan dan Kebudayaan sejalan dengan pemikiran Ki Hadjar Dewantara, karena pendidikan menghilangkan belenggu kesenjangan dan membentuk karakter calon pemimpin bangsa. Merdeka belajar merupakan salah satu bentuk implementasi nilai-nilai pembentuk karakter bangsa dimulai yang dari pembenahan sistem pendidikan dan metode belajar. Diharapkan merdeka belajar dapat memberikan perubahan ke arah yang lebih baik serta memberikan manfaat pada lingkungan.