bluuebunny/crossref_metadata_2025 huggingface dataset:
The Functions of Films for Children as Learning Media in Children's Education
Authors: Pratiwi Dyani Prades , Saniro Roma Kyo Kae , Hawa Andina Meutia
Published: June 2023

Children's interest in learning should be continuously enhanced. Selecting suitable learning media is very important to support the increased interest in learning. A film can be one of the learning media that offers advantages for achieving a quality children's education process. This study aims to discuss the functions of films for children in children's education. The method used is descriptive qualitative with literary studies techniques. The study results show that there are three functions of films for children as learning media, namely film as a media for language learning, film as a media for character building, and film as a media for introducing multiculturalism. Film can stimulate children's imagination so that children can think actively and creatively. However, the functions of films are inseparable from the role of parents and teachers in selecting films and methods or techniques for presenting films so that children remain active learners.
Komunikasi Pengelola Destinasi Wisata Puncak Pato dengan Pemerintah dalam Upaya Meningkatkan Kunjungan Wisatawan
Authors: Nurdiansyah Firgi , Chatra Emeraldy , Sarmiati Sarmiati
Published: June 2023

The increase in tourists which is the main driver of the tourism sector requires the cooperation of all stakeholders consisting of the government and direct cooperation from both the business world and from the private sector. The increase in tourist visits is certainly inseparable from communication activities between actor’s manager of the Puncak Pato tourist area and the government. This communication is important to achieve maximum results in increasing tourist visits to Puncak Pato. The research method used is a phenomenological approach with a constructivism paradigm. The theory used is the Interpretative Phenomenological Analysis theory from Jonathan Smith. Based on the results of the research, it shows that the important concept of communication between managers of the Puncak Pato tourist destination is openness in conveying correct information to the government, an attitude of supporting the government in communication activities and carrying out communication activities with the government in the form of meetings.
Komunikasi Dinas Perpustakaan dan Dinas Pariwisata dalam Menyelamatkan Naskah Kuno Surau Latiah Kota Solok
Authors: Pebriona Sevri , Chatra Emeraldy , Arif Ernita
Published: June 2023

This study discusses the communication carried out by the Library Service and the Tourism Office which were carried out at the same time, with the same goal, namely saving the ancient manuscripts of surau Latiah in Solok City, and not knowing each other that there was a multiplicity of activities. The purpose of the article is to find out the communication experiences and the most meaningful concepts from the communication experiences of the two agencies. The research method is a qualitative Husserl phenomenological approach with a constructivism paradigm. Data obtained from observations, in-depth interviews and documentation. The results of the study show that the communication experience carried out by the two agencies is different. The most meaningful concept from the communication experience of the two agencies is effective communication in the form of persuasive communication that is influenced by other people who are considered important and carried out by means of verbal and non-verbal communication so that there is a change in the attitude of the owner of the manuscript so that he wants to submit the ancient manuscript of Surau Latiah.
Pengaruh Work-Life Balance terhadap Profesionalisme melalui Mediasi Kepuasan Kerja pada Aparatur Sipil Negara (ASN) di Lingkungan Pemerintah Kabupaten Tapanuli Selatan
Authors: Harahap Sri Wahyuni , Turnip Kaiman , Lubis Rahmi
Published: June 2023

The aim of this research is to analyze the mediating role of job satisfaction in the relationship between work-life balance and the professionalism of ASNs. These two factors are critical to study because an imbalance between work and life may result in unprofessional behavior, and job dissatisfaction may also lead to unprofessionalism at work. The study utilized quantitative research methods, employing Structural Equation Model (SEM) data analysis techniques using AMOS version 22 software. Stratified random sampling was used to select 300 ASNs as respondents, and data were collected using professionalism, work-life balance, and job satisfaction scales. The results indicated that job satisfaction significantly mediated the relationship between work-life balance and professionalism. This study highlights the importance of job satisfaction as a mediator in maintaining the professionalism of ASNs and suggests the need for policies to improve work-life balance in order to enhance professionalism in the workplace. Relevant keywords include job satisfaction, work-life balance, professionalism, ASNs, and Structural Equation Model.
Citra Perempuan Kolonial dalam Kehidupan Beragama di Sumatera Timur, 1870-1942
Authors: Suriani Suriani , Afrina Tiara Desthy , Febriani Wilda
Published: June 2023

The opening of tobacco plantations in East Coast Sumatra in 1870 became a major factor in the creation of ethnic, cultural, and religious diversity in there. All the Malays there were Muslim, then the Europeans came with their Christianity, which was followed by most of the Batak people, the Indians brought Hinduism and Sikhism, and the Chinese brought Buddhism. East Coast Sumatra is a pluralistic region, but there has never been a conflict between ethnicities or religions. Very interesting. However, the reality of the religious life of the people at that time had never been revealed in detail. Furthermore, during the 1930 census it was recorded that there were 4.293 Europeans in Medan and 2.001 of them were women, but their presence in the religious sphere has not been exposed. Therefore, this study aims to narrate the image of colonial women in religion in East Coast Sumatra. The images of colonial women in this study are all forms of mental, spiritual, and daily behaviour expressed by women in religion, including the outward appearance that appears in women and their religious activities in East Coast Sumatra in the period 1870-1942. This study uses the historical method, and the primary data are the Dutch Colonial Government Report (verslag),Volkstelling 1930, maps, newspapers, bulletins and magazines, photographs depicting the religious life of the people of East Sumatra in the period 1870-1942.
Chemical protection of potatoes from fungal diseases, taking into account the stability of the variety
Authors: Barkov V. A. , Belov D. A. , Zeyruk V. N. , Belov G. L. , Derevyagina M. K. , Vasilyeva S. V. , Bukharova A. R.
Published: June 2023

In the conditions of the Moscow region in 2019-2022 the effectiveness of funicides of new chemical classes in the potato protection system against rhizoctoniosis, late blight and alternariosis was studied, taking into account the different resistance of varieties (Gulliver, Grant, Sante) to diseases. Potato tubers were treated with the preparation Idikum, SC before planting, its biological effectiveness in reducing the incidence of rhizoctoniosis in the full germination phase was 76.7-95.7 %. It was found that the effectiveness of the preparation depended on the degree of disease development, the stability of the variety and the phase of crop development. In addition, when etching the planting material with Idikum, SC, there was no population of rhizoctosis sclerotia and the spread of dry rot on tubers of the new yield significantly reduced (1.6-5.0 times) compared to the control. The proposed scheme of potato protection in conditions of epiphytotic development of late blight and early blight based on combined chemicals Metaxil, SP, Inside, SC with contact fungicides Raek, CE, Talent, SC, Tirada, SC showed high efficiency in reducing harmfulness of the diseases, which allowed to extend the growing season of plants, to ensure a higher yield of potatoes, its marketability and quality. The use of preparations provided an increase in yield by 36.3-47.5 %, depending on the prevailing weather conditions of the growing season and on the variety in relation to the control (without treatment). It has been established that the biological effectiveness of the protection scheme in reducing the degree of late blight and early blight increased from susceptible to relatively stable varieties and, accordingly, this trend continued with an increase in yield. Higher increases were obtained on unstable varieties Gulliver and Sante (10.6-13.5 t /ha, or 45.7-56.0 %), lower – on the relatively stable variety Grand (7.8 t/ha, or 36.0 %). The contribution of the application of the protection scheme to the overall variation of gross and marketable potato yields was 76.5-81.0 %, gene-type - 7.9-12.5 %, the interaction of these factors – 3.7-4.7 %.
The influence of different doses and ratios of mineral fertilizers on the yield of winter rye in the Urals
Authors: Shishkov D. G. , Olekhov V. R. , Vasbieva M. T.
Published: June 2023

Winter rye is an important crop of the Non-Chernozem belt of Russia, the productivity of which depends on the use of fertilizers. The paper presents data on the agronomic and economic efficiency of cultivating Falenskaya 4 winter rye under conditions of long-term use of mineral fertilizers. The studies were carried out in 2019-2021 in Perm Region on sod-podzolic heavy loamy soil in a long-term stationary experiment based on a reduced factorial design (6x6x6) with a wide range of doses and NPK ratios. The highest yield in 2019 was obtained in N30P120K120 variant (3.07 t/ha), the highest payback of mineral fertilizers by grain was noted in N90 and N30P30K30 variants (6.00 and 5.69 kg of grain). The highest yield and payback of grain in the conditions of 2021 and for two years of research in average was obtained in the variant N90: in 2021, 3.01 t/ha and 13.96 kg of grain, for 2 years average – 2.95 t/ha and 9.82 kg of grain. The efficiency of nitrogen fertilizers has been proved by a regression equation for two years average, phosphoric and potash fertilizers did not have a significant effect. The rise in the yield increase occurred up to a nitrogen dose of 90 kg/ha and amounted to 0.42 t/ha at N90. The highest payback by grain was noted among nitrogen treatments – by N30 (7.3 kg of grain), with each increase in doses by 30 kg/ha, this indicator decreased linearly by 1.3 kg. The highest profitability over the years of research was obtained in the variant without fertilizers– 60 %, over two years in average. The profitability of using N90 was higher compared with the control only in 2021 – 50 % versus 43 %. All the studied doses of nitrogen used separately provided positive profitability, but the most cost-effective was the use of N30 and N60 – profitability was 52 and 45 %, respectively.
Assessment of the biological value of forages according to the control tests of milk and its use in the organization of feeding of dairy cattle
Authors: Baranova N. S. , Kirikova T. N. , Davydova A. S. , Kazakov D. S.
Published: June 2023

The article presents the results of the assessment of the biological usefulness of feed according to the control tests of milk. Scientific research was carried out in LLC "Minskoye" of the Kostroma district of the Kostroma region on a population of 369 cows of the Kostroma and Black-and-White breeds according to the seasons of the year. The authors found that in terms of the level of digestible protein in lactating cows, there is an imbalance in almost all seasons of the year, so most animals are prone to diseases associated with metabolic disorders. The level of rumen acidity in animals of the Koroma breed was more stable (pH = 6.2-6.4) in all seasons of the year, which indicates a lower likelihood of developing acidosis, in contrast to Black-and-White breed cows. Based on the indicators of milk control tests, insufficient supply of raw protein to cows of the Kostroma and Black-and-White breeds during the milking period was established. The highest daily milk yields (more than 30 kg of milk) were obtained from cows in the first and second periods of lactation in all seasons of the year. In animals with a level of availability of digestible protein of 10.3-10.9 g/MJ, there is a normal ratio of fat: protein (1.26:1), with a profitability level of 66.11%, while animals with an insufficient level availability of digestible protein of 10.2 g/MJ and less, had the level of profitability of milk production 73.93 and 86.44%, respectively. When the level of availability of digestible protein is more than 11.0 g/MJ in animals, the likelihood of acidosis increases. Evaluation of the biological value of feeds according to control tests of milk during the period of control milkings will allow monitoring the energy and protein nutrition of animals.
Amatör Futbolcularda Zihinsel Antrenmanın Zihinsel Dayanıklılığa Etkisinin İncelenmesi
Authors: PARLAK Necmettin
Published: June 2023

Bu araştırmada amatör futbolcularda zihinsel antrenmanın zihinsel dayanıklılığa etkisinin incelenmesi amaçlanmıştır. Bu araştırmanın evrenini Aydın ilinde futbol oynayan amatör sporcular, örneklemini ise kolay ulaşılabilir örneklem yöntemine göre belirlenmiş, Aydın’ın merkez ilçesinde faaliyet gösteren amatör spor kulüplerde oynayan 127 erkek, 41 kadın, toplam 168 amatör futbolcu oluşturmaktadır. Bu araştırmanın amaçları doğrultusunda çalışmamızda zihinsel antrenman envanteri, zihinsel dayanıklılık envanteri ve araştırmacılar tarafından oluşturulan kişisel bilgi formu kullanılmıştır. Verilerin analizinde doğrusal regresyon analizi, frekans, yüzde ve güvenirlik katsayısı hesaplamaları, anova analizi ve t testleri yapılmıştır. Analiz sonucu Zihinsel Temel Beceriler ile güven arasında orta seviyede olumlu yönlü anlamlı ilişki olduğu, Zihinsel Performans Becerileri Beceriler ile güven arasında orta düzeyde olumlu yönlü anlamlı ilişki olduğu , Kişilerarası Beceriler ile güven arasında orta düzeyde olumlu yönlü anlamlı ilişki olduğu, Kendinle Konuşma ile güven arasında düşük düzeyde olumlu yönlü anlamlı ilişki olduğu ,, Zihinsel Canlandırma ile güven arasında orta düzeyde olumlu yönlü anlamlı ilişki olduğu görülmektedir. Zihinsel Temel Beceriler ile kontrol arasında çok düşük düzeyde olumsuz yönlü anlamlı ilişki olduğu, Zihinsel Performans Becerileri ile kontrol arasında orta düzeyde olumsuz yönlü anlamlı ilişki olduğu, Kişilerarası Beceriler ile kontrol arasında çok düşük düzeylerde olumsuz yönlü anlamlı ilişki olduğu görülmektedir. Sporda zihinsel antrenman boyutları ile sporda zihinsel dayanıklılık boyutları arasında istatistiksel olarak anlamlı ilişki olmadığı gözlenmektedir. Sonuç olarak katılımcıların zihinsel antrenman süreçlerinin zihinsel dayanıklılık üzerinde anlamlı etkisi olduğu ve zihinsel antrenman arttıkça zihinsel dayanıklılığında arttığı gözlemlenmektedir.
Idiosyncratic Drug-Induced Liver Injury: From Pathogenesis to Risk Reduction
Authors: Mazerkina I. A.
Published: June 2023

Idiosyncratic drug-induced liver injury (iDILI) is a rare and poorly predictable adverse drug reaction that may lead to death or liver transplantation in severe cases.

The aim of the study was to review contemporary concepts of the immune-mediated pathogenesis of iDILI and possible ways to predict and prevent the risk of developing this condition.

The liver is characterised by high immune tolerance due to a complex of mechanisms involving various cells (antigen-presenting cells, T-cells), cytokines, and other molecules, which prevents severe immune responses to xenobiotics entering the body. Previous research has shown that iDILI results from a combination of multiple synergistic unfavourable factors that impair liver immune tolerance at different levels. These factors include the hepatotoxicity-associated chemical properties of medicines and the individual characteristics of the patient, including the genetically determined structure and function of the adaptive immune system components. Since iDILI has a multilevel and multifactor pathogenesis, it is difficult to determine a risk biomarker for a particular medicine. According to the literature review, the risk of hepatotoxicity of a drug candidate and/or a metabolite can be reduced at the preclinical level by assessing the ability to cause mitochondrial damage, form non-covalent bonds, produce reactive oxygen species, and release damage-associated molecular patterns (DAMPs). The association of iDILI with gene polymorphisms in patients receiving certain medicines has a high negative predictive value and can be used in clinical practice to rule out iDILI or identify hepatotoxic medicinal products in polypharmacy. The identification of the allele combinations associated with an increased risk of iDILI seems promising for enhancing the predictive value of genetic studies and may be used in personalised medicine.
Zeugung auf Probe? – Selektion vor der Schwangerschaft?
Authors: Eibach Ulrich
Published: June 2023

Various moral considerations with respect to PGD, i. e. normative ones as well as those about the predictable and possible consequences, clearly converge to provide a persuasive argument against any form of legalising PGD. In particular, what counts against PGD are the affirmation of clearly negative judgments about the quality of life and the selection of embryos according to those judgments; the questioning of the human dignity and human rights of early human embryos; and the resultant qualification of the prohibition to kill. This puts us on a slippery slope and undermines more and more the protection of life for the weakest members of our society. Thus there cannot be a right to a »healthy child« by way of PG D. From a Christian-moral perspective, the government and parliament would be well advised not to leave the regulation of the use of PGD to the professional medical organisations but to outlaw PGD in the planned Reproductive Medicine Act.
Unterschiede im Krankheitsverständnis und transkulturelle Pflege
Authors: Kuhn Barbara
Published: June 2023

Disease, its origins, and its influence on human beings are seen differently in different cultures. Different terms are used to describe disease, and there are examples of very mythological or religious pictures and metaphors to understand it. Patients from foreign cultures use them to describe their disease to themselves and to their caregivers. Transcultural care challenges nurses to detect commonality as well as differences; under no circumstances must they impose their beliefs on patients from other cultures. Instead, carers need to see their patients’ peculiarities as an expression of their individual needs. As a background M. Leininger’s theory of transcultural care is described and criticized. Finally, there are some practical considerations for concrete nursing situations.
» Rationierung im Gesundheitswesen«
Authors: Schultheiss Carlo
Published: June 2023

Several authors have recently argued for a broader debate about rationing of health care. Because the term »rationing of health care« is used in different ways and because not all definitions presented in literature seem to be equally acceptable a primary task for the debate is to formulate an adequate concept of rationing. Making use of the method of conceptual explication this paper proposes a definition that tries to make the idea of rationing as a »limited allocation« of goods more precise. Having defined »health care rationing« by refering both to philosophical as well as economic considerations some alternative definitions are discussed.
Der Mensch als Person – zwischen Technik und Ethik
Authors: Müller Gerhard Ludwig
Published: June 2023

Modem biotechnology has multiplied beyond imagination the range of human possibilities, even with respect to human beings themselves. Yet no human technology is able to provide the answers to its own moral and religious challenges. Beyond the dimension of means there ist the dimension of ends – of discovering the answers to the basic questions about human existence. For the sake of all human beings biotechnology must engage in a dialogue with philosophical and theological anthropology.
The Role of Oxidative Stress in the Induction and Development of Psoriasis
Authors: Blagov Alexander , Sukhorukov Vasily , Guo Shuzhen , Zhang Dongwei , Eremin Ilya , Orekhov Alexander
Published: June 2023

Psoriasis cannot be completely cured and is often difficult to diagnose, which is why the search for new effective therapies and diagnostics is a highly relevant area of research. To identify new therapeutic compounds, the first step is to study the role of various factors underlying the development of psoriasis. One such factor is oxidative stress. In this review, we will consider the role of oxidative stress at different stages of psoriasis development, as well as biomarkers of oxidative stress that can potentially be used in the diagnosis of psoriasis and antioxidants, which are likely to be applied in the treatment of this disease.
Melatonin Receptor 1B and Corticosteroid Receptor Polymorphisms in Infertile Women with Implantation Failure and Miscarriages
Authors: Robeva Ralitsa , Marinova Elena , Andonova Silvia , Nikolaev Georgi , Savov Alexey , Tanev Dobromir , Nikolov Gueorgui , Konakchieva Rossitza
Published: June 2023

Background: The development of assisted reproductive techniques has significantly improved fertility chances in many women, but recurrent implantation failure (RIF) and miscarriages (RM) might preclude successful pregnancy. Alterations in the intrinsic secretory patterns of melatonin and cortisol influence reproduction in humans, and imperfection of receptor — dependent signaling may additionally compromise the hormonal effects. Therefore, the present study aims to investigate the influence of certain melatonin and cortisol receptor polymorphisms in infertile women. Methods: A total of 111 female infertile patients suffering from implantation failure and/or miscarriages were genotyped for MTNR1B rs1562444, MTNR1Brs10830962, GCCR rs41423247, and GCCR ER22/23EK variants. Additionally, 106 female volunteers were genotyped for the same polymorphisms. Results: The allele and genotype distribution of the investigated polymorphisms did not differ between infertile women and the control group. Significantly more women with history of RIF have MTNR1B rs1562444 G-allele-containing genotypes in comparison to AA carriers (19.3% vs. 3.6%, p = 0.004). The minor allele of the ER22/23EK variant was more frequent in infertile patients with three or more unsuccessful implantation attempts than in other women (12.5% vs. 2.4%, p = 0.025). Conclusions: Melatonin receptor 1B polymorphisms might affect embryo implantation and early pregnancy loss, while their influence on late pregnancy complications needs further evaluation. The possible association between the cortisol receptor ER22/23EK variant and recurrent implantation failure might help to differentiate women who could benefit from corticosteroid treatment.
The Impact of Heparin Therapy in Deceased Donors on Early Graft Survival for Kidney and Liver Recipients: A Clinical Trial Study
Authors: Latifi Marzieh , Pourhosein Elahe , Rahban Habib , Khajavi Mohammadreza , Dehghani Sanaz
Published: June 2023

Background: Significant hemodynamic, hormonal, and metabolic impairment of a brain-dead organ donor is often associated with the deterioration of graft viability. This study aimed to compare the effect of heparin therapy as a therapeutic dose after brain death confirmation on early graft survival in kidney and liver recipients. Method and Materials: The deceased donors were sorted into two groups based on their D-dimer level. After confirming brain death, one group was given a heparin injection (case group), while the other group did not receive any heparin (control group). A total of 71 brain death donors and matched kidney and liver transplants were included in the case group. A total of 43 brain death donors and matched kidney and liver transplants were included in the control group. A total of 5000 units of heparin were administered every 6 hours to the deceased donor case group. Results: The mean age of the case and control groups were 36.27 ± 16.13 and 36.15 ± 18.45, respectively. An independent t test showed that there were no differences between the number of procured organs in both groups (p = 0.29). There was no significant difference between the graft survival rate and the doses of heparin injection to the liver recipients (p = 0.06). However, a significant difference was revealed between the graft survival rate and the dose of heparin injection (p = 0.004) in kidney recipients. Conclusions: The data suggest that administering low therapeutic doses of heparin to donors before organ donation may potentially prevent thrombosis and provide a protective benefit. We showed that heparin therapy had no significant effect on the number of donated organs and graft survival.
Pathomorphological diagnosis of primary cutaneous CD4-positive small/medium T-cell lymphoproliferative disorder: a 28-case series
Authors:   National Research Center for Hematology, Moscow, Sherstnev A.A. , Kovrigina A.M. ,   National Research Center for Hematology, Moscow, Gorenkova L.G. ,   National Research Center for Hematology, Moscow
Published: June 2023

Introduction. Primary cutaneous CD4+ lymphoproliferative disorder of small and medium cells (PC CD4+ T-LPD small/medium cell) is a new entity identified in the WHO classification published in 2017. The aim of the research was to characterize morphological and immunohistochemical features of PC CD4+ T-LPD small/medium cell. Materials and methods. The study examined 28 skin biopsies from 13 males and 15 females with PC CD4+ T-LPD small/medium cell using histological and immunohistochemical methods. Results. We detected growth pattern to be of nodular, focal–diffuse, and diffuse types. Each case was characterized by significant T-cell lymphoid infiltration with an immunophenotype of follicular T-helper cells (Tfh-immunophenotype), the number of B-cells varying. Conclusion. PC CD4+ T-LPD from small and medium cells is a rare disease that requires further study to determine the criteria for diagnosis and treatment. Keywords: primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder, T follicular helper cells, immunophenotype
Osseointegration properties of titanium implants with different pore diameters: experimental study
Authors:   Privolzhsky Research Medical University, Nizhny Novgorod, Orlinskaya N.Yu. , Gerasimov S.A. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Aleynik D.Ya. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Zakharova D.V. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Kulakova K.V. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Charykova I.N. ,   Privolzhsky Research Medical University, Nizhny Novgorod, Morozova E.A. ,   Privolzhsky Research Medical University, Nizhny Novgorod
Published: June 2023

Introduction. Additive technologies make it possible to create implants to replace bone defects. Determining the optimal parameters of a porous structure remains an urgent issue. The experimental research aimed to study the biocompatibility of implants made of titanium alloy with different pore diameters. Materials and methods. The study was carried out in two stages. The first stage included an in vitro study carried out on test cultures of diploid human fibroblasts to assess the cytotoxicity of the titanium alloy, from which samples were made for the second stage in vivo. The in vivo study was performed on three groups of rabbits (n=18), which received samples of the developed implants. The average age of subjects was 7±1 months, the weight being 4.675±258 g. All samples were 4 mm in diameter and 6 mm high. In group 1, the pore size was 100 μm; in group 2 – 200 μm; and in group 3 – 400 μm; the porosity was 55%, 62%, and 70%, respectively. The animals were sacrificed on day 90 after placement of the samples. Histological, morphological, and electron microscopic studies were performed to assess the osseointegrative properties of the implants. Results. In the in vitro study, we detected no toxic effects of the material on the test culture. In the in vivo study, the histological analysis did not reveal inflammation in peri-implant tissues in any of the groups. The morphological study showed a newly formed tissue in the area of the formed defect which consisted of young bone trabeculae with osteoblasts located on their surface. In group 3, we found the greatest prevalence of mature bone trabeculae. The samples with a 400-μm pore diameter revealed the largest area of filling the implant with newly formed bone tissue. Conclusion. Samples with a pore diameter of 400 μm have the highest osteointegrative properties. Keywords: osteointegration, biocompatibility, titanium implants, additive technologies, 3D-printing
ФОРМУВАННЯ ЦИФРОВОЇ КОМПЕТЕНТНОСТІ СТУДЕНТІВ ФІЛОЛОГІЧНИХ СПЕЦІАЛЬНОСТЕЙ: ІНТЕРАКТИВНІ ФОРМИ ОРГАНІЗАЦІЇ І МЕТОДИ НАВЧАННЯ
Authors: Арістова Наталія
Published: June 2023

Посилення ролі цифрової грамотності й цифрової компетентності для працездатного населення зумовлено швидкою цифровізацію всіх сфер життя сучасного суспільства загалом і змушеним переходом на змішану та/або віддалену форму навчання. Зважаючи на актуальність проблеми формування цифрової компетентності студентів філологічних спеціальностей мета дослідження полягає в теоретичному обґрунтуванні доцільності застосування інтерактивних форм організації і методів навчання в їхній підготовці в закладах вищої освіти. У статті також здійснено науковий аналіз змісту й сутності понять «цифрова компетентність» та «цифрова компетентність педагогічного й науково-педагогічного працівника», а також уточнено сутність поняття «цифрова компетентність студентів філологічних спеціальностей». Задля досягнення мети авторкою було використано комплекс теоретичних методів дослідження (аналіз, систематизація й узагальнення результатів науково-педагогічних досвіду українських і зарубіжних учених). Авторкою проаналізовано досвід українських і зарубіжних дослідників щодо застосування ефективних форм організації і методів навчання, які сприяють ефективному формуванню цифрової компетентності студентів філологічних спеціальностей. Основу цифрової компетентності студентів філологічних спеціальностей становлять знання базових правил цифрової безпеки, інформаційної етики та гігієни; уміння і навички безпечного спілкування з усіма учасниками освітнього процесу в цифровому середовищі закладу освіти; уміння і навички використовувати інформаційні технології (у тому числі – цифрові), що гарантуватиме ефективність пошуку, аналізу та синтезу необхідної інформації з різних джерел, які представлені в цифровому форматі; уміння і навички розробляти навчальний (освітній) контент у цифровому форматі. Визначено інтерактивні форми організації та методи навчання, які сприяють ефективному формуванню цифрової компетентності, а саме: лекції, практичні та семінарські заняття, організовані у формі дискусії або диспуту, метод «перевернутий клас», метод проєктів, метод дискусії, метод презентації та метод дидактичної гри.
A Comprehensive Review of Multiple Criteria Decision-Making (MCDM) Methods: Advancements, Applications, and Future Directions
Authors:   Biju Patnaik University of Technology (BPUT), Rourkela, Odisha, India, Sahoo Sushil Kumar , Goswami Shankha Shubhra ,   Biju Patnaik University of Technology (BPUT), Rourkela, Odisha, India
Published: June 2023

This research paper presents a comprehensive review of Multiple Criteria Decision-Making (MCDM) methods, encompassing their advancements, applications, and future directions. The study begins with an introduction emphasizing the significance of MCDM in complex decision-making scenarios. Through a systematic literature review, recent developments in MCDM techniques are examined, including multi-objective methods, fuzzy-based approaches, data-driven models, and hybrid methodologies. The strengths and limitations of each method are critically analyzed. Furthermore, the paper investigates the diverse applications of MCDM in domains such as business, engineering, environment, healthcare, and public policy, highlighting the practical implications through real-world case studies. The study then identifies emerging trends and challenges in MCDM research, discussing the integration of MCDM with emerging technologies, enhancing robustness and adaptability, addressing uncertainty, and identifying unexplored domains for potential application. This comprehensive review serves as a valuable resource for decision-makers and researchers, providing insights into the advancements, applications, and future directions of MCDM methods.
Metode dan cara penyelesaian hadis kontradiksi
Authors: ajid Nur
Published: June 2023

Dalam artikel ini menjelaskan bagi mana penyelesaian sebuah hadis yang bertolak belaka dengan dalil lain atau yang sering kita sebut ialah Hadis Mukhtalif Hadis mukhtalif ialah hadis yang kontradiktif, secara bahasa hadis mukhtalif ialah, Mukhtalif yang berarti bertentangan atau kontradiktif dan kemudian hadis yang sering kali kita artikan dengan segala sesuatu yang berasal dari Nabi Saw. baik berupa ucapan, pekerjaan, sifat dan ketetapan itu di namakan hadis, berarti mukhtalif hadis ialah hadis-hadis Nabi yang kontradiktif atau yang saling bertentangan dengan dalil lain seperti hadis berkontradiktif dengan hadis, hadiskontradiktif dengan dalil Al- Quran dan alin sebagainya. Dalam pembahasan kali ini penulis akan membahas tentang Metode dan cara penyelesaian hadis-hadis yang kontra diktif. Dalam hadis yang kontradiktif pastilah ada beberapa teori atau metode untuk menemukan titik temu atau menyeleesaikan hadis tersebut. Adapun metode-metide yang penulis gunakan dalam pembahasan kali ini ialah Metode Al-Jam'u Wa Al-Taufiq dan Naskh wa Al-Mansukh.
CHST6 is differentially expressed in central nervous system metastasis.
Authors: Mamoor Shahan
Published: June 2023

Metastasis to the brain occurs in a significant fraction of patients with solid tumors including breast cancer and metastatic melanoma (1-3). We mined published RNA-sequencing and microarray data (4, 5), comparing primary and brain metastatic tumor transcriptomes for the discovery of genes associated with metastasis to the CNS. We found that carbohydrate sulfotransferase 6, encoded by CHST6, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. Study of microarray data (5) revealed conserved differential expression of CHST6 in CNS metastasis in patients with metastatic melanoma. CHST6 mRNA was present at increased quantities in metastasis to the brain in humans with breast cancer. Expression of CHST6 in primary tumors of the breast was correlated with patient overall survival. Modulation of CHST6 expression may be relevant to the biology by which tumor cells metastasize to the brain in humans with solid tumors with propensity for the CNS including breast cancer and metastatic melanoma.
Corpora for investigations in Phonetics, Phonology and Psycholinguistics: Brazilian Portuguese, American English and British English corpora with phonetic and psycholinguistic variables
Authors: Post da Silveira Amanda
Published: June 2023

Fundamentally empirical and lexical studies are becoming more and more frequent in recent years, so researchers are often forced to do the work of collecting and making various corpora for specific purposes, which, in most cases, are not made public to serve other studies. In addition, it is necessary to have corpora that have comparable variables and that control a sufficient number of psycholinguistic and phonetic variables. In this work, I present three corpora that serve the purposes of several research objects, which present psycholinguistic and phonetic variables (eg lexical frequency, phonetic transcription, number of syllables), also presenting thousands of types and millions of lexical tokens, for Brazilian Portuguese, American English and British English.
VOTE_12_10_2022_Supplementary material_REV15.5.23
Authors: Reho Matteo
Published: June 2023

Supplementary material
PERAN [PENDIDIKAN AGAMA KRISTEN (PAK) DALAM LINGKUNGAN MASYARAKAT
Authors: Keo Aksamina
Published: June 2023

Pendidikan Agama Kristen (PAK) adalah pelayanan gereja yang sangat penting untuk mendidik dan melatih anggota gereja atau orang kristen yang berpartisipasi dalam proses mengenal akan Tuhan. Gereja ada dalam masyarakat yang majemuk
Exploring the Recontextualisation Process in Developing the Plant Biotechnology Course: A Bernsteinian Analysis
Authors: Mwale Mafunase , Shumba Overson
Published: June 2023

The purpose of this study was to explore the recontextualisation of knowledge in the development process of the plant biotechnology course with an aim of understanding how knowledge is to be framed and classified in the course. The plant biotechnology course was developed for the students enrolled in the department of biological sciences. The course was also included in the curriculum for the students training to be teachers of biology in secondary schools in Zambia. The aim of any training is to prepare the students for their future profession. Therefore, a need to understand how the plant biotechnology course was developed in relation to meeting the objectives of a teacher training curriculum. Studies have indicated that, to effectively prepare the students to teach biology in secondary schools, the students need to experience a pedagogic practice characterized with both weak and strong framing and a weak classification between the discourses. The research question which guided the study was: How is knowledge recontexualised in the development process of the BT 440 course? Interviews were used to collect the data. Bernstein’s classification, framing, recognition and realization rules were used to analyze and interpret the findings. An inductive approach was used to analyse the transcript. Atlas ti 8 was used to analyse the transcript. The findings of the analysis indicated that the analysis of the interview data has revealed that the control relations (framing) between the agents in terms of hierarchical rules, knowledge selection, sequencing, pacing and the evaluation criteria were all strongly framed (F+). In terms of the relations between discourses, the classification was weak (C-) in the inter-disciplinary, intra-disciplinary and in the inter-discursive relations, indicating a weak recognition and realisation of the text.
Pandangan Agama Kristen Terhadap Seks Di Luar Nikah
Authors: Hau'oni Shindi
Published: June 2023

Kata seks tidak asing lagi dalam kehidupan. Seks adalah baik, jika dilakukan setelah menikah. Tetapi banyak orang terjerumus ke dalam perilaku seks sebelum menikah, dengan latar belakang faktor yang berbeda dan tidak memperdulikan nilai dan norma dalam masyarakat, serta pandangan agama terhadap perilaku mereka.
TXNIP is a differentially expressed gene in brain metastatic human breast cancer.
Authors: Mamoor Shahan
Published: June 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that thioredoxin interacting protein, encoded by TXNIP, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. TXNIP mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of TXNIP in primary tumors was correlated with patient overall, distant metastasis-free and recurrence-free survival. Modulation of TXNIP expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Tantangan Tantangan Etika Pemerintahan
Authors: mukmin
Published: June 2023

Pada pelaksanaan penyelengaraan pemerintahan, ada banyak hal yang belum jalan sesuai dengan yang diinginkan. Banyaknya penyelewengan yang terjadi dalam penyelenggaraan pemerintah, disebabkan oleh melemahnya etika pemerintahan sehingga diperlukan strategi penguatan etika pemerintahan. Dengan memberikan fokus yang besar terhadap penggunaan etika dan moral dalam bertindak, maka sistem tata kelola pemerintahan yang baik atau dapat tercapai. Penelitian ini menggunakan metode studi kepustakaan. Berdasarkan penelitian yang dilakukan dapat ditarik kesimpulan bahwa dalam rangka penguatan etika pemerintahan dibuat beberapa aturan sebagai strategis dalam upaya percepatan perwujudannya etika pemerintahan.
Hadis mukhtalif
Authors: hudin Solah
Published: June 2023

Perbedaan dalam hadits mukhtalif sering kali menjadi masalah dalam pemahaman hadits, terutama bagi umat Muslim yang ingin mempelajari ajaran Islam secara lebih mendalam. Oleh karena itu, artikel ini bertujuan untuk membahas hadits mukhtalif. Dalam penelitian ini, penulis menggunakan metode kajian teoretis dengan menganalisis hadits dari segi sanad, matan, dan konteks sejarah.
Metrologi penyelesaian hadis mukhtalif
Authors: hudin Solah
Published: June 2023

Sebagai sumber utama dalam mempelajari ajaran Islam, hadits seringkali menjadi subjek diskusi dan kajian. Namun, dalam pemahaman hadits, sering kali ditemukan perbedaan antara hadits mukhtalif yang menyebabkan kebingungan. Oleh karena itu,penelitian ini bertujuan untuk membahas tiga pasang hadits mukhtalif.
Establishing an Early Indicator for Data Sharing and Reuse
Authors: Piekniewska Agata , Haak Laurel L. , Henderson Darla , McNeill Katherine , bandrowski anita , Seger Yvette
Published: June 2023

Funders, publishers, scholarly societies, universities, and other stakeholders need to be able to track the impact of programs and policies designed to advance data sharing and reuse. With the launch of the NIH data management and sharing policy in 2023, establishing a pre-policy baseline of sharing and reuse activity is critical for the biological and biomedical community. Toward this goal, we tested the utility of mentions of research resources, databases, and repositories (RDRs) as a proxy measurement of data sharing and reuse. We captured and processed text from methods sections of open access biological and biomedical research articles published in 2020 and 2021 and made available in PubMed Central. We used natural language processing to identify text strings to measure RDR mentions. In this article, we demonstrate our methodology, provide normalized baseline data sharing and reuse activity in this community, and highlight actions authors and publishers can take to encourage data sharing and reuse practices.
Korean Wave TV Dramas and Turkish Remakes of K-Dramas: The Politics of Intercultural Communication and Cultural Meanings of Modernization
Authors: Sarı Engin
Published: June 2023

Television, through drama and series, is the most powerful and pervasive storyteller and culture producer of our time. The culture-producing function of television and the culture constructed by TV are most clearly visible in national adaptations of globally produced programs and formats. For more than a century, Korea and Turkey have been trying to modernize and integrate into contemporary civilization while preserving their own culture. In recent years, Korea has succeeded in producing its popular culture within the national culture industry and spreading it around the world, and this popularity has been called the Korean Wave. In Turkey, there is a high interest in K-Dramas, one of the cultural products of the Korean Wave. The reason for this interest is that the modernization efforts and cultural characteristics of the two countries are similar. The basis of this similarity is the social desire to preserve its culture while modernizing. The subjects of K-dramas are mainly family and romantic relationships, and identity problems of the youth. These are cultural manifestations of the process of social modernization and are addressed in television dramas. In this article, Dr. Romantic, the most popular K-Drama of recent years both at national and global level, and its Turkish remake Town Doctor (Kasaba Doktoru) are analyzed from the perspective of cross-cultural comparison. This analysis is done around the strategies of cultural adaptation. The analysis with these strategies shows how these nations interpret their idiosyncrasies, interculturality and modernization As a result of the analysis, it is argued that Korean drama portrays scientific, professional, ethical and personal conflicts without taking a clear stand in favor of any of them, while Turkish remake emphasizes romance and melodrama and advocates a conservative modernizationist policy of interculturality.
Experiment ended
Authors: end exp
Published: June 2023

Experiment ended --
Uncover rigorous application range of phenomena measure method to avoid adding extra unverifiable things into reality for explaining measured discrepancy
Authors: guo wei
Published: June 2023

Today, the scientific community comprehensively accepts adding many extra unverifiable things into reality, e.g. extra mass: dark matter, extra energy: dark energy, extra position: superposition, extra dimensions, or even extra parallel reality. Considering reality is not understood completely, adding something into reality's unknown part is indeed a shortcut for explaining some measured discrepancy, but such behaviors are likely to distort the instinct of reality. We report any inherent measured discrepancy involving an indirect measure method that relies on an artificially-defined equivalence, e.g. inertia mass indirectly measures mass by equating mass with force/acceleration. Time measure relies on an equivalence between time and some phenomena, e.g. swing of pendulum, fall of sands or electron jumping between two states. Since Galileo, mathematical equal sign is introduced so naturally between different physical properties. We argue any such equivalence only holds true within a limited phenomena range. Although some method's application range has been summarized, e.g. inertia mass only applies to 'macro, low-speed, inertia-system', we state such scattered descriptions collected from experience are not rigorous. We propose a general frame that can identify a more rigorous application range. Hence, any inherent measured discrepancy results from the measured phenomena exceeding the method's rigorous application range, e.g. remote objects actually exceed the Doppler effect's application range. By ignoring this, large-scale red shift inevitably misleads us to the dark energy's existing necessity. Similarly, dark matter only logically exists to expand the rigorous application range of dynamical mass.
Survey on Ecological Ethics Status of Vietnamese Students of Economic and Business Administration Sector in the Current Period
Authors: Le Thi Hong Thuan  , Linh Nguyen Thuy , Thuy Nguyen Thi Bich , Thien Nguyen Chi , Mai Ngo Thanh , Hoan Nguyen Thi
Published: June 2023

The ecological ethics of students today is not a new issue but has always been of concern, especially during the explosive development of information technology. This study provides information on the ecological ethics situation, the contents, methods, and forms of surveying the ecological ethics status of Vietnamese students in economics and business administration. Through the study, the ecological ethics status of Vietnamese students majoring in economics and business administration has been shown on the following issues: (1) Perception, (2) Consciousness, (3) Standards, and (4) Eco-ethical behavior, thereby proposing some solutions to improve ecological ethics for Vietnamese students in the field of economics and business administration in the current context.