bluuebunny/crossref_metadata_2025 huggingface dataset:
El pan del futuro: cambio climático, agricultura y alimentación en América Latina
Authors: Maletta Héctor
Published: May 2023

¿Habrá más hambre en el futuro, a raíz de los cambios esperados en el clima? En este artículo se reseñan las previsiones sobre cambio climático en el mundo y en América Latina, preparadas por el Panel Intergubernamental de Cambio Climático (IPCC) de la ONU, y sus probables consecuencias sobre la agricultura y la seguridad alimentaria de América Latina, estimadas por dos métodos: modelos ricardianos y modelos de evaluación integrada. También se discute brevemente algunas cuestionesconexas, como la subida en el nivel del mar, la deglaciación andina, y la dinámica del fenómeno del Niño, el posible efecto del cambio climático sobre el campesinado andino y otros pequeños productores de subsistencia, así como problemas conceptuales y metodológicos relacionados con estos análisis. También se exploran factores no climatológicos que están en juego, como tendencias demográficas, cambios agrarios y crecimiento del ingreso, entre otros. Contra lo que podría suponerse, las perspectivas no son catastróficas ni mucho menos.
Más allá de la cholificación: movilidad social ascendente entre los aimaras de Unicachi en Lima
Authors: La Cruz Bonilla Juan
Published: May 2023

Este artículo propone reflexionar sobre la noción de «cholificación» —bajo la cual se ha venido entendiendo el cambio cultural del migrante andino en la ciudad— a través de un caso distintivo de movilidad social ascendente ocurrido en Lima: el de los migrantes aimaras del distrito puneño de Unicachi. La experiencia de los unicachinos refleja un caso particular de movilidad social ascendente, donde la asimilación de la modernidad y el éxito económico no han llevado a una ruptura con la cultura de origen. Todo lo contrario: la nueva generación de jóvenes nacidos en Lima y provenientes de hogares hoy solventes refleja haber reinventado su identidad en la capital, participando activamente en la reproducción de la tradición paterna e incluso propiciándola. Más aún, un acercamiento a estas familias refleja que, a pesar de su éxito económico, persiste en su praxis e imaginarios una brecha social extraeconómica que las lleva a diferenciarse de la clase alta y media alta de Lima. Se aprecian así los límites del proceso de cholificación en tanto integración social: el éxito económico del migrante andino no lo haría sentirse igual a los sectores acomodados limeños.
Abriendo las cajas negras del análisis foucaultiano: una invitación a la Teoría del Actor-Red
Authors: Pereyra Omar
Published: May 2023

En este artículo deseo hacer una introducción a la Teoría del Actor-Red (Action-Network-Theory o ANT). Como un proyecto de sociología del conocimiento y de la ciencia que se expande a otras esferas de lo social, la ANT tiene en la perspectiva foucaultiana un contrincante natural. Por ello, presentaré un contraste entre ambas perspectivas. Esta comparación se centra en las diferencias entre sus fundamentosontológicos (cuerpos y sujetos versus actantes y actores), sus distintas formas de aproximarse a estos (genealogía vs. traslado/traducción), y finalmente sus consecuentes metáforas o imágenes utilizadas para describir el mundo (instituciones o sistemas vs. redes o ensamblajes). Argumentaré que, aunque la perspectiva foucaultiana es inicialmente más ambiciosa que la ANT, al final acaba traicionándose a sí misma por tener, en la práctica, una fijación en el poder sobre el sujeto, y en consecuencia, por tener una visión más rígida de los sistemas que lleva a oscurecer los desvíos, negociaciones o accidentes que ocurren en el proceso de producción. Ilustraré mi argumento haciendo referencia a distintos trabajos que se guían por la perspectiva foucaultiana. También se señalarán algunas críticas a la ANT.
¡Buena puntería!... pero ¿ese era el blanco? : Entrevista con Danilo Martuccelli
Authors: Villa Julio
Published: May 2023

No contiene resumen.
Populismo: el ruido y la ira
Authors: Gutiérrez Vera Daniel
Published: May 2023

El presente artículo refiere a las propuestas de Ernesto Laclau que revisan la consideración tradicional acerca del populismo. En marzo de 2012, Laclau estuvo de visita en Ecuador y ofreció una conferencia magistral en FLACSO. El artículo a continuación responde en parte a lo dicho por Laclau. Se esbozan críticas a algunos de sus planteamientos.
Entre madres-adolescentes y adolescentes-madres: un análisis de su trayectoria de vida y los factores que influyen en su configuración
Authors: Mastro Naccarato Irene Del
Published: May 2023

Analizar las consecuencias de la maternidad adolescente en los ámbitos educativo, laboral y familiar, así como los factores que influyen en la reconfiguración de la trayectoria de vida de la madre adoles- cente tras el embarazo, son los principales objetivos de esta investigación realizada entre los años 2012 y 2013. A partir de trece entrevistas en profundidad a madres adolescentes con hijos entre 2 y 5 años de edad y provenientes de distintos estatus socioeconómicos de Lima, encontramos dos trayectorias tipo: la trayectoria madre adolescente y adolescente-madre. Los hallazgos de este estudio sugieren la importancia del estatus socioeconómico, los roles de género, las concepciones en torno a la adolescencia y al ejercicio de la maternidad, así como las vivencias, características y aspiraciones propias de cada mujer como factores que intervienen en la configuración de la trayectoria de vida de las madres adolescentes.
Entre la incertidumbre y el individualismo. Ética científica de la adversidad y nanotecnología en el Perú
Authors: Zárate Vásquez Julio Sebastián
Published: May 2023

Hacer ciencia en el Perú es enfrentarse a la adversidad. En una coyuntura que se caracteriza por suprecariedad institucional y en la que, al mismo tiempo, se ha comenzado a demandar inversión en ciencia, tecnología e innovación, cabe preguntarse por los modos en que los actores superan día a día estas dificultades. En ese sentido, la propuesta consiste en acercarse a estos actores del conocimiento a partir del estudio de un caso particular: el de los expertos en nanotecnología. La hipótesis propuesta es que, para superar dichas adversidades, los expertos han desarrollado ciertos mecanismos individuales y colectivos que tienen como base una ética científica particular que se expresa a través del interés individual por generar y acceder a más conocimientos. A partir de ello, se intentará caracterizar el panorama institucional de la ciencia y la tecnología en relación con la investigación científica.
Un avance transformador: la ampliación del aeropuerto internacional Jorge Chávez y el reasentamiento del asentamiento humano «El Ayllu», Callao
Authors: De la Puente Burlando Lorena
Published: May 2023

En el mundo, los Estados transforman el uso de su territorio a través de proyectos de infraestructura con la promesa de generar mayor desarrollo para el país. Sin embargo, tal proceso acarrea costos sociales locales, pues las poblaciones —usualmente marginales— que habitan los territorios de interés para el Estado se ven obligadas a abandonarlos al no poder reproducir sus actividades tradicionales. Si bien los Estados poseen grandes capacidades para promover los mencionados proyectos, aún carecen de mecanismos institucionales suficientes como para evitar impactos locales. Si bien los conflictos sociales son respuestas frecuentes a esta incapacidad, en un nivel general el avance del Estado es exitoso. La presente investigación busca responder a cómo se construye el vínculo entre los funcionarios públicos y la población en riesgo, para legitimar la transformación del territorio e invisibilizar los costos sociales del proceso. Argumentamos que el uso del discurso del desarrollo es un instrumento disponible para ganar legitimidad. El caso elegido es el reasentamiento del asentamiento humano «El Ayllu», a causade la ampliación del aeropuerto internacional Jorge Chávez en el Callao, Perú.
Camisea, compensaciones y diversificación de actividades de subsistencia en la comunidad nativa de Cashiriari (Cusco-Perú)
Authors: Del Castillo Tafur Cynthia
Published: May 2023

El proyecto de gas de Camisea-PGC, uno de los proyectos de hidrocarburos más grandes de Latinoamérica, se explora en el sureste de la Amazonía peruana, en territorio donde habita población indígena machiguenga. La comunidad nativa machiguenga de Cashiriari, lugar donde se basa mi estudio, atraviesa significativos procesos de cambio social, entre otras razones, como consecuencia de la entrada de dinero por las compensaciones recibidas del Consorcio Camisea y por la contratación de mano de obra local nativa para trabajar en las operaciones del proyecto. El dinero ha adquirido un papel protagónico en las transacciones e interacciones de los machiguengas. La diversificación de actividades de subsistencia que generen ingresos monetarios es ahora un rasgo de los hogares machiguengas en Cashiriari, particularmente entre las mujeres, lo que incrementa su carga laboral en el hogar. Hay una percepción generalizada en la comunidad del desarrollo material que viven, pero también del debilitamiento de sus recursos naturales y tradiciones culturales.
Delgada línea: entre el clientelismo y la confianza institucional. Estudio en dos distritos de Lima Metropolitana
Authors: Cohaila Ramos Edwin
Published: May 2023

El presente artículo trata de observar la existencia de ciertas similitudes entre las relaciones de confianza que puedan establecerse entre los individuos y su institución política local, con formas habituales de relacionarse que lindan con el clientelismo político. Se observarán ciertas semejanzas que apuntan a cuestionar si el clientelismo puede tener cabida como una forma de establecer relaciones, crear vínculos y acercar la institución política al individuo. Se observará la construcción de relaciones y vínculos en dos distritos de un mismo estrato zonal en Lima Metropolitana, a través de herramientas cualitativas y cuantitativas. Se notará que la forma habitual de relacionarse aprendida sigue presente y moviliza las formas de actuar a los individuos; por tanto los vínculos con características clientelaresson plausibles de generar relaciones de confianza.
Microstructures in Shocked Quartz: Linking Nuclear Airbursts and Meteorite Impacts
Authors: Hermes Robert E. , Wenk Hans-Rudolf , Kennett James P. , Bunch Ted E. , Moore Christopher R. , LeCompte Malcolm A. , Kletetschka Gunther , Adedeji A. Victor , Langworthy Kurt , Razink Joshua J. , Brogden Valerie , Van Devener Brian , Perez Jesus Paulo , Polson Randy , Nowell Matt , West Allen
Published: May 2023

Many studies of hypervelocity impact craters have described the characteristics of quartz grains shock-metamorphosed at high pressures of >10 GPa, but in contrast, few studies have investigated shock metamorphism at lower shock pressures. In this study, we test the hypothesis that low-pressure shock metamorphism occurs in near-surface nuclear airbursts and that this process shares important characteristics with impact-cratering events. To investigate low-grade shock microstructures, we compared quartz grains from Meteor Crater, a 1.2-km-wide impact crater, to those from near-surface nuclear airbursts at the Alamogordo Bombing Range, New Mexico in 1945 and Kazakhstan in 1949/1953. This investigation utilized a comprehensive analytical suite of high-resolution techniques, including transmission electron microscopy (TEM) and electron backscatter diffraction (EBSD). Meteor Crater and the nuclear test sites all exhibit metamorphosed quartz grains with closely-spaced, sub-micron-wide fractures that appear to have formed at low shock pressures. Importantly, these micro-fractures are closely associated with Dauphiné twins and are filled with amorphous silica (glass), widely considered to be a classic indicator of shock metamorphism. Thus, this study confirms that glass-filled shock fractures in quartz form during near-surface nuclear airbursts, as well as crater-forming impact events, and by extension, it suggests they also may form in near-surface cosmic airbursts.
Efficient D---A Type Dye-Sensitizer Based on the Benzothiadiazole Moiety: A Computational Study
Authors: Fatma Mustafa M. , Mahmoud Abdel-Latif K. , Abdel-Khalek Ahmed A. , Kühn Oliver
Published: May 2023

The design of highly efficient sensitizers is one of the most significant areas in dye-sensitized solar cell (DSSC) research. We have studied a series of benzothiadiazole-based D-π-π-A organic dyes, putting emphasis on the influence of the donor moiety on the DSSC’s efficiency. Using linear response time-dependent density functional theory (TDDFT) with the CAM-B3LYP functional different donor groups were characterized in terms of electronic absorption spectra and key photovoltaic parameters. As a reference a dye has been considered which has a benzothiadiazole fragment linked via thiophene rings to a diphenylamine donor and a cyanoacrylic acid acceptor. The different systems are first studied in terms of individual performance parameters, which are eventually aggregated into the power conversion efficiency. Here only the amino-substituted species shows a modest increase, whereas the dimethylamino case even shows a decrease.
Consumer Acceptance of Fungus-Resistant Grape Varieties – An Exploratory Study Using Sensory Evaluation Test Among Consumers in Germany
Authors: Kiefer Christoph , Szolnoki Gergely
Published: May 2023

This study investigated the factors that influence consumer acceptance of fungus-resistant grape varieties (FRGV) in Germany. The qualitative research methodology involved conducting semi-structured interviews including sensory evaluation test with focus groups consisting of 48 consumers, and the data were evaluated using content analysis. The findings revealed that the attractiveness of a grape variety is determined by four distinct attributes. Furthermore, FRGV can be made more attractive to consumers by using denominations based on established grape varieties or by using and associating them with their sensory patterns. The sensory acceptance of FRGV varies significantly across consumer segments and vinification methods. Providing relevant information about the benefits of resistant grape varieties has a positive impact on consumer acceptance, and the level of interest and relevance varies by the target group. The study suggests that it is possible to enhance consumer acceptance by offering attractive grape varieties, targeting group-specific sensory profiles and engaging in storytelling campaigns that educate consumers about the advantages of resistant grapes.
Transition From Screw Type to Edge Type Misfit Dislocations at InGaN/GaN Heterointerfaces
Authors: Li Quantong , Minj Albert , Ling Yunzhi , Wang Changan , He Siliang , Ge Xiaoming , He Chenguang , Guo Chan , Wang Jiantai , Bao Yuan , Liu Zhuming , Ruterana Pierre
Published: May 2023

We have investigated the interfacial dislocations in InxGa1–xN/GaN (0 ≤ x ≤ 0.20) heterostructures using diffraction contrast analysis in a transmission electron microscopy. The analysis indicate that the structural properties of the interface dislocations depend on the indium composition. For lower indium composition up to x = 0.09, we observed that the screw-type dislocations and dislocation half loops occurred at the interface even though the former do not contributes toward elastic relaxation of the misfit strain in the InGaN layer. With the increase of indium composition (0.13 ≤ x ≤ 0.17), in addition to the network of screw-type dislocations, edge-type misfit dislocations were found generated with their density gradually increasing. For higher indium composition (0.18 ≤ x ≤ 0.20), all the interfacial dislocations are transformed into a network of straight misfit dislocations along the <10-10> directions leading to partially relaxation of the InGaN epilayer. The presence of dislocation half loops may be explained by slip on the basal plane, the formation of misfit dislocations are attributed to punch-out mechanism.
Oncological Outcomes after Laparoscopic and Open Liver Resection in patients with Colorectal Liver Metastases: A Single Centre Propensity Score Matched Study
Authors: Diaz-Garcia Alberto , Gordon-Weeks Alex , Young Robert , Gilbert Timothy , Rehman Adeeb , Malik Hassan , Fenwick Stephen , Jones Robert P , Diaz-Nieto Rafael
Published: May 2023

Abstract
Introduction
Minimally invasive approaches to oncological liver resection is common in many hepatobiliary centres. This study aims to compare the key oncological and survival outcomes of patients with colorectal liver metastases (CRLM) undergoing laparoscopic or open resections using propensity score matching (PSM).
Methods
A single-centre retrospective study was performed using a prospective database of patients undergoing liver resection for CRLM between January 2016 and December 2019. Different co-variates were selected for matching using PSM. Pre-matching and post-matching analyses were compared. Surgical and survival outcomes were analysed.
Results
In total, 303 patients who met the inclusion criteria were identified: 214 underwent open liver resection (OLR) and 91 laparoscopic liver resection (LLR). LLR had a significantly reduced length of intensive treatment unit (ITU) and overall in-patient stay but longer pringle and operative times. In the unmatched cohort, the median overall and disease-free survival time was significantly longer in patients undergoing laparoscopic compared with open surgery. A PSM model demonstrated significantly reduced blood loss and length of hospital stay, with a significantly greater Pringle and operative time in the LLR group. Differences seen in overall and disease-free survival were lost with propensity score matching, possibly due to lack of bi-lobar disease within the minimally invasive group.
Conclusion
In selected patients with CRLM, LLR presents similar survival and oncological outcomes with the advantages of the short-term results associated with the laparoscopic approach.
Marine Sulfated Glycans Inhibit the Interaction of Glycosaminoglycans with SARS-CoV-2 Omicron XBB Variant S-Protein
Authors: He Peng , Song Yuefan , Jin Weihua , Li Yunran , Xia Ke , Kim Seon Beom , Farrag Marwa , Dwivedi Rohini , Bates John T. , Pomin Vitor H. , Linhardt Robert J. , Dordick Jonathan S. , Zhang Fuming
Published: May 2023

Keywords: Marine sulfated glycans; SARS-CoV-2; Omicron XBB.1.5, Spike protein; Heparin
Silting Process and Loss of Posidonia oceanica Meadows in the Tyrrhenian Calabria Waters (Southern Italy)
Authors: Ietto Fabio , Pellicone Gaetano , Cantasano Nicola
Published: May 2023

In the Mediterranean Sea, there are two critical issues affecting marine benthic biocenosis: the sedimentation process and the increasing trend in marine biodiversity loss. These processes are very marked along the western side of Calabria coastline where siltation is one of the main reasons for the regression of Posidonia beds in the regional coastal waters. This research aims to investigate the relationships between the geomorphological features of the debris source areas, represented by fluvial basins, and the distribution of Posidonia meadows. So, a geomorphological study of the Tyrrhenian fluvial basins with area greater than 200 km2 and its correlation with the mapping of the meadows in the Calabria Tyrrhenian waters was carried out. Furthermore, in order to assess the increased level of burial in a Posidonia oceanica meadow and its health state over time, a program of Posidonia monitoring was undertaken between 2000 and 2010, in a test area located in the Marine Regional Park of Isca (Calabria, Southern Italy). The results of this survey highlighted that, at the beginning of the study period, for a silting rate of 4 - 5 cm/year, the meadow suffered a reduction of its photosynthetic ratio with a rate of mortality of 50%. In the following years, the siltation rate reach 12 cm/year in 2010 and the meadow began to disappear. Therefore, the marine pollution by sedimentation represents a serious factor for the regression of Posidonia oceanica meadows, enhancing the risk of a gradual loss in marine biodiversity.
A Systematic Review and Bayesian Meta-Analysis of Medical Devices Used in Chronic Pain Management
Authors: Shetty Ashish , Delanerolle Gayathri , Deng Chunli , Cavalini Heitor , Yang Xiaojie , Thillainathan Anish , Bouchareb Yassine , Boyd Amy , Phiri Peter , Shi Jian
Published: May 2023

Chronic non-cancer pain is a highly debilitating condition affecting approximately 20% of the global population. Chronic pain may lead to significant physical disability, emotional distress, social isolation and financial burden. Whilst. pharmacological therapies remain the cornerstone of pain management in non-cancerous chronic pain, factors including the current opioid epidemic have led to non-pharmacological techniques becoming a more attractive proposition. We explored the prevalence of medical device use and their treatment efficacy in non-cancer pain management. A systematic methodology was developed, peer reviewed and published in PROSPERO (CRD42021235384). Key words of medical device, pain management devices, chronic pain, lower back pain, back pain, leg pain and chronic pelvic pain using Science direct, PubMed, Web of Science, PROSPERO, MEDLINE, EMBASE, PorQuest and ClinicalTrials.gov. All clinical trials, epidemiology and mixed methods studies that reported the use of medical devices for non-cancer chronic pain management published between the 1st of January 1990 and the 30th of April 2022 were included. 13 studies were included in systematic review, of these 6 were used in the meta-analysis with 173 participants. Our meta-analysis for pain reduction in each study showed that transcutaneous electrical nerve stimulation combined with instrument-assisted soft tissue mobilization treatment and pulsed electromagnetic therapy produced significant treatment on chronic lower back pain patients. Pooled evidence revealed the use of medical device related interventions resulted in 0.7 degree of pain reduction under a 0-10 scale. Significant improvement in disability scores, with a 7.44 degree reduction in disability level compared to a placebo using a 50 score range was also seen. The application of medical devices in patients with chronic pain has gained popularity due to increasingly cost effective techniques, minimally invasiveness and greater awareness of risks associated with pharmacological management. Our analysis has shown that the optimal use of medical devices in a sustainable manner requires further extensive research, needing larger cohort studies with greater gender parity, in a more diverse range of geographical locations.
Severity Predictions for Intercity Bus Crashes on Highway using a Random Parameter Ordered Probit Model
Authors: Kim Kanghyun , Hong Jungyeol
Published: May 2023

As intercity buses are a mode that moves large scaled occupancy between regions, it accounts for the mode share-means for mid to long-distance movement in South Korea. However, the study on intercity bus safety needs to be more extensive, and safety policies are carried out based on traditional probability models without considering the data characteristics of bus accidents. Therefore, in this study, the Random Parameter Ordered Logit model was applied to derive fixed parameter factors that have the same effect on the severity of intercity bus accidents and random parameters that consider the heterogeneity of unique attributes by accident. It also analyzed the marginal effect of intercity bus accident severity. As a result of the study discovered that the influencing factors that reflect heterogeneity with Random Parameters were driver’s condition: drowsiness, vehicle size: medium, crash type: vehicle-pedestrian accident, road condition: wet pavement, and log form of AADT. The random parameter ordered logit model was traditionally found to be more suitable than the ordinal logit model, which only reflects fixed factors and more reliable predictions considering the heterogeneity of accident characteristics for each observation.
A Review of a Candidates for a Validation Data Set for High-Assay Low-Enrichment Uranium Fuels
Authors: DeHart Mark D. , Bess John D. , Ilas Germina
Published: May 2023

Many advanced reactor concept designs rely on high-assay low-enriched uranium (HALEU) fuel, enriched up to approximately 19.75% 235U by weight. Efforts are underway by the US government to increase HALEU production in the United States to meet anticipated needs. However, very little data exists for validation of computational models that include HALEU, beyond a few fresh fuel benchmark specifications in the International Reactor Physics Experiment Evaluation Project. Nevertheless, there is other data with potential value available for developing into quality benchmarks for use in data and software validation efforts. This paper reviews the available evaluated HALEU fuel benchmarks and some of the potentially relevant benchmarks for fresh highly enriched uranium. It then introduces experimental data for HALEU fuel irradiated at Idaho National Laboratory, from relatively recent irradiation programs at the Advanced Test Reactor. Such data should be evaluated and, if valuable, collected into detailed benchmark specifications to meet the needs of HALEU-based reactor designers.
First Description of a Mixed Brugada Pattern in Inferior Leads
Authors: Bermejo Valdés Alejandro Jesús , Iglesias Gutiérrez Sara , Teja Ruiz Basilio
Published: May 2023

Brugada Syndrome is a cardiac channelopathy closely related to lethal arrhythmias and sudden death in people without underlying structural pathology. The diagnosis is usually assumed with electrocardiographic patterns strictly limited to the right precordial leads, V1 or V2; but this is not so at all. In our article, we describe the clinical case of a patient with a novel and different electrocardiographic presentation: the typical diagnostic pattern was presented in a lower lead of the electrocardiogram, and next to it, another pattern was presented in a contiguous lead. In addition, we propose the possible association of a structural pathology (non-compaction cardiomyopathy) with Brugada Syndrome, since both share a possible common genetic origin in the SCN5A gene.
Synthesis and Investigation of Novel Optical Active SiO2 Glasses with Entrapped YAG:Ce Synthesized by Sol-Gel Method
Authors: Skruodiene Monika , Kemere Meldra , Inkrataite Greta , Leimane Madara , Ramanauskas Rimantas , Skaudzius Ramunas , Sarakovskis Anatolijs
Published: May 2023

We present a crack-free optically active SiO2 glass-composite material containing YAG:Ce synthesized by a modified sol-gel technique. A glass-composite material consisting of yttrium aluminum garnet doped with Ce3+ (YAG:Ce) entrapped into a SiO2 xerogel. This composite material has been prepared by sol–gel technique with modified gelation and drying process to obtain crack-free optically active SiO2 glass. The concentration of the YAG:Ce was from 0.5 to 2.0 wt%. All synthesized samples were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM) techniques. The luminescence properties of the obtained materials were studied.
Design and Operation of a Gripper for a Berthing Task
Authors: Titov Alexander , Russo Matteo , Ceccarelli Marco
Published: May 2023

The idea of an extension of life for CubeSats is proposed to reduce space debris in a low-earth orbit. In this work, a gripper is designed for geometry-based grasping in berthing tasks. The grasping operation is outlined for square- and rectangle-profiled CubeSats. Equilibrium conditions are used to choose fingertips shape and parameters for grasping the CubeSat body. A design scheme is proposed to provide the required accuracy. A design concept is developed into a lab prototype by using low-cost 3D printing technique, and a mock-up grasping task that is representative of the berthing operation is evaluated with the lab prototype. Center-mass hanging setup for the prototype and grasped body is used to evaluate the impact of grasping, partially replicating the conditions in space by reducing the effect of gravity on the system.
Targeting M2-TAM via STAT3/NF-kB/AKT Signaling Pathway With Oxaliplatin, Retinoic Acid, and Libidibia ferrea -Loaded Extracellular Vesicles From Macrophages 1 Down-Regulates Murine Colon Cancer Metastasis
Authors: De Carvalho Thaís Gomes , Lara Pablo , Jorquera-Cordero Carla , Schomann Timo , Aragão Cícero Flávio Soares , Oliveira Artur de Santana , Garcia Vinicius Barreto , Souza Shirley Vitória de Paiva , Marques Isabelle de Lima , Lira Soares Luiz Alberto , Guedes Paulo Marcos Da Matta , De Araújo-Júnior Raimundo Fernandes
Published: May 2023

Despite the numerous advances in target therapy for the treatment of colorectal cancer, aggressive colorectal cancer remains an incurable disease whose negative modulation of the immune system in the tumor microenvironment is still critical for improving the patient's prognosis. Extracellular vesicles (EVs) have received attention for their use as cell-membrane-camouflaged nanoparticles and drug delivery systems in nanomedicine derived by nearly all cell types for intercellular communication and regulation in the tumor microenvironment (TME). In this study, M1 Macrophage EVs (M1EVs) were used as nanocarriers of oxaliplatin (M1EV1) associated with retinoic acid (M1EV2) and Libidibia ferrea (M1EV3), or combined together with retinoic acid and Libidibia ferrea (M1EV4) to evaluate their antiproliferative and immunomodulatory potential on CT-26 and MC-38 colorectal cancer cell lines, as well as their capacity to prevent metastases in mouse models of colorectal cancer such as allographic and peritoneal. Tumors were evaluated by qRT-PCR and immunohistochemistry. The cell death profile and epithelial-mesenchymal transition process (EMT) were analyzed in vitro in colorectal cancer cell lines. Polarization of murine macrophages (RAW264.7 cells) was also carried out. M1EV2 and M1EV3 used alone or especially combined (M1EV4) downregulated the tumor progression by TME immunomodulation, leading to a decrease in primary tumor size and metastases in peritoneum, liver and lungs. STAT3, NF-kB and AKT were the major genes downregulated by systems of M1EVs. Tumor-associated macrophages (TAM) switched M2 phenotype (CD163) towards M1 (CD68) reducing levels of IL-10, TGF-β and CCL22. Furthermore, malignant cells showed overexpression of FADD, APAF-1, caspase-3, and E-cadherin, and decreased expression of MDR-1, survivin, vimentin, CXCR4, and PD-L1 after treatment with systems of M1EVs. The results obtained in this study provided evidence that EVs from M1 antitumor macrophages can transport drugs and increase their immunomodulatory and antitumor activity by stimulating activation or blockage of pathways involved in cell proliferation, migration, cell survival, and drug resistance processes.
Synthesis and Characterization of an Environmentally Friendly Phenol-Formaldehyde Resin Modified With Waste Plant Protein
Authors: Li Hanyin , Wang Sen , Zhang Xiang , Wu Hao , Wang Yujie , Zhou Na , Zhao Zhijie , Wang Chao , Zhang Xiaofan , Wang Xian , Li Cheng
Published: May 2023

To develop a lower-cost, excellent performance, and environmentally friendly phe-nol-formaldehyde (PF) resin, soybean meal was used to modify PF resin, and soybean meal-phenol-formaldehyde (SMPF) resins were prepared. Their physicochemical properties and curing performance were investigated, showing that SMPF resins have higher curing tempera-tures than PF resin. The Fourier transform infrared spectroscopy (FTIR) results indicated that the cross-linking reaction occurred between the amino groups of soybean protein and the hy-droxymethyl phenol. Moreover, with the addition of soybean meal, the viscosity of SMPF in-creased while the gel time decreased. It is worth mentioning that SMPF-2 resin has favorable viscosity, short gel time, low curing temperature (135.78 °C), and high water resistance and bonding strength (1.01 MPa). Finally, all the plywoods bonded with SMPF resins have good water resistance and bonding strength, which could meet the Standard (GB/T 17657-2013, type I) for plywood. The optimized SMPF resins showed the potential application to replace part of PF resin in the wood industry.
Анализ динамики эпидемического процесса COVID-19 в мире за неделю с 20.05.2023 г. по 26.05.2023 г.
Authors: Зимирова Анастасия , Поспелов Михаил , Иванова Александра , Дмитриева Людмила , Чумачкова Елена , Карнаухов Игорь , Щербакова Светлана , Кутырев Владимир
Published: May 2023

В обзоре представлен анализ эпидемиологической ситуации в странах мира по COVID-19 за неделю с 20.05.2023 г. по 26.05.2023 г.
PENINGKATAN MUTU PEMBELAJARAN GERAK DASAR TARI KELAS VII MELALUI VIDEO ANIMASI 2D MENGGUNAKAN METODE ADDIE
Authors: Iriyanto Dede , Suarna Nana , Raditya Danar Dana Raditya Danar Dana
Published: May 2023

ABSTRAK

Kurikulum Merdeka menempatkan Seni Tari sebagai mata pelajaran yang diberikan pada jenjang menengah pertama (SMP) kelas VII di SMPN 1 Gunung Jati. Kualitas pembelajaran seni tari dipengaruhi oleh komponen-komponen pendidikan dalam meningkatkan mutu pembelajaran, salah satunya adalah dengan memanfaatkan media pembelajaran. Subjek pada penelitian ini dilakukan pada siswa kelas VII di SMPN 1 Gunung Jati yang menempuh mata pelajaran Seni Tari. Permasalahan selama ini diantaranya adalah; (1) Media pembelajaran gerak dasar tari sulit menampilkan gerak dan suara dalam halaman media cetak, (2) Kurangnya pendidik mata pelajaran seni tari dari lulusan jurusan pendidikan seni tari, (3) Masih dominan pendidik menggunakan metode ceramah dan tanya jawab tanpa variasi lain dalam proses pembelajaran gerak dasar tari. Tujuan penelitian ini adalah; (1) Untuk menampilkan media pembelajaran gerak dasar tari dengan gerak dan suara, (2) Untuk meningkatkan pendidik mata pelajaran seni tari dari lulusan jurusan pendidikan seni tari, (3) Untuk meningkatkan dominan pendidik pembelajaran seni tari gerak dasar tari. Metode penelitian ini menggunakan metode ADDIE yang memiliki 5 tahapan, yaitu: Analysis, Design, Development, Implementation dan Evaluation. ADDIE merupakan metode penelitian yang cocok digunakan untuk mengembangkan media pembelajaran karena berorientasi produk sehingga sesuai digunakan untuk mengembangkan video animasi dua dimensi sebagai media pembelajaran. Hasil uji normalitas (Shapiro-Wilk) menunjukan nilai signifikan 0.082, hal ini menunjukkan bahwa hasil uji normalitas nilai signifikannya lebih dari 0.05. Maka dari itu H0 diterima, sehingga implementasi media pembelajaran animasi dua dimensi berdampak terhadap peningkatan mutu pembelajaran.

Kata Kunci: Media Pembelajaran, Video Animasi 2D, Gerak Dasar Tari, Metode ADDIE
Adult Patient Satisfaction with Nursing Care Services and Associated Factors Among Admitted Patients at Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia, 2022: A Cross-Sectional Study
Authors: Bogale Bantalem Amanu , Ahmed Sindew Mahmud , Gebrekidan Aynie Birhane , Bogale Getachew Amanu
Published: May 2023

Background
Providing holistic nursing care and ensuring patient satisfaction have become essential health performance indicators all across the world. Notwithstanding several efforts to improve patient satisfaction with nursing care, the approach in developing countries, including Ethiopia, is still insufficient. This study was aimed to assess the level of adult patients’ satisfaction and to identify factors affecting satisfaction.
Materials and Methods
This cross-sectional study included 407 participants, who were selected using a simple random sampling technique. The sample was distributed using proportional allocation for each selected adult inpatient department. Participants were interviewed using a modified structured Amharic version of the ‘Newcastle satisfaction with nursing scale’. Data analysis was made by SPSS version 26. Bivariate and multivariable logistic regression analysis was used.
Results
The overall level of patient satisfaction with nursing care services was 54.3%. Respondents who had no formal education (P = 0.010), being male (P = 0.041), free service consumers (P < 0.001), health insurance users (P < 0.001), was significantly associated with satisfaction with nursing care. In addition, patients who had previous admission history (P = 0.001), Governmental workers (P < 0.001), and patients admitted in the medical ward (P = 0.010) were associated with patient dissatisfaction with the nursing care services.
Conclusions and recommendations:
This study revealed that adult patient satisfaction with nursing care services was rated low. Previous admission history, higher education level, paying cash for services, and private and governmental workers were significant predisposing factors to dissatisfaction with nursing care. On the other hand, patients with no formal education, free service consumers and being male were significant predictors of satisfaction with nursing care services. Therefore, it is recommended that the hospital administration better emphasize the needs and expectations of the patient.
Immature mandarin orange extract increases the amount of Hyaluronic acid in human skin fibroblast and keratinocytes
Authors: Furukawa Tomoko , Yokono Chisako , Nomura Yoshihiro
Published: May 2023

Immature mandarin orange is thinned in order to maturation of orange. To use immature mandarin orange as a cosmetic functional material, we investigated the seasonal fluctuation changes in hesperidin and narirutin levels and antioxidant capacity of immature mandarin oranges, and the effects on human skin cells. The contents of hesperidin from Aoshima, Otsu, and Shonan gold, is higher at about a month after flowering. Shonan gold has higher content of narirutin to compere that of Aoshima and Otsu. We found the addition of immature mandarin orange extracts to the human skin fibroblasts and keratinocytes, gene expression level of hyaluronic acid synthase and the hyaluronic acid contents in the medium are higher than that of the control. It was suggested that hesperidin in immature mandarin orange enhances the ability of skin cells to produce hyaluronic acid. Our findings indicate that the immature mandarin orange is a characteristic material on cosmetics and functional foods.
Ketorolac removal through photoelectrocatalysis using TiO2 nanotubes in water system
Authors: Rodríguez Sebastián Oyarzabal , Aceves Luis Erick Coy , Daniel Jesus Eduardo , Sánchez-Salas Jose Luis , Martínez-Huitle Carlos Alberto , Ramírez-Rodrigues Milena Maria , Lopez Monica Cerro
Published: May 2023

Ketorolac, a highly persistent NSAID of environmental concern, was significantly removed from water (80% removal) through photoelectrocatalysis where titanium dioxide nanotubes prepared by Ti foil electrochemical anodization at 30 V were used as photoanodes. 15 mgL-1 ketorolac solutions in a 0.05 M Na2SO4 aqueous medium were subjected to irradiation from a 365 nm light with an intensity of 1 mWcm-2 and under an applied potential of 1.3 V (vs. Hg/Hg2SO4/sat.K2SO4)) at pH 6.0. When each process (photo and electrocatalysis) was carried out separately, less than 20% drug removal was achieved as monitored through UV-vis spectrophotometry. Through scavenging experiments, direct oxidation on the photogenerated holes and oxidation by hydroxyl radicals formation were found to play a key role on ketorolac´s degradation. Chemical oxygen demand (COD) analyses also showed a significant COD decreased (68%) since the initial COD value was 31.3 mg O2/L and the final COD value was 10.1 mg O2/L. A 48% mineralization was also achieved, as shown by total organic carbon (TOC) analyses. These results showed that electrodes based on titania nanotubes are a promising alternative material for simultaneous photocatalytic and electrocatalytic processes in water remediation.
Insights from a cross-sectional binational study comparing obesity among Colombians in their home country and in the U.S.
Authors: Devia Carlos , Flórez Karen R. , Costa Sergio A. , Huang Terry T-K
Published: May 2023

Background: Latinos in the United States (U.S.) represent a heterogeneous minority population disproportionally impacted by obesity. Colombians in the U.S. are routinely combined with other South Americans in most obesity studies. Moreover, most studies among Latino immigrants in the U.S. solely focus on factors in the destination context, which largely ignores the prevalence of obesity and contextual factors in their country of origin, and warrant transnational investigations.
Methods: Using 2013-17 data from the New York City Community Health Survey (NYC CHS, U.S.) and the National Survey of the Nutritional Situation (ENSIN, Colombia), Colombians that immigrated to the U.S. and are living in NYC (n=503) were compared to nonimmigrant Colombians living in their home country (n=98,829). Prevalence ratios (PR) for obesity (BMI ≥30 kg/m2) by place of residence were estimated using multivariable logistic regression adjusting for socio-demographic characteristics and daily consumption of sugar-sweetened beverages.
Results: The prevalence of obesity was 49% greater for immigrant Colombians living in NYC when compared to nonimmigrant Colombians living in in their home country (PR=1.49; 95% CI 1.08, 2.07). Colombian immigrant men in NYC were 72% more likely to have obesity compared to nonimmigrant men living in their home country (PR=1.72; 95% CI 1.03, 2.87). No significant differences were found in the adjusted models among women.
Conclusions: Colombian immigrants in NYC exhibit a higher prevalence of obesity compared to their nonimmigrant counterparts back home and sex strengthens this relationship. More obesity research is needed to understand the immigration experience of Colombians in the U.S. and the underlying mechanisms for sex difference. Public health action focused on women in Colombia and both Colombian men and women immigrants in the U.S. is warranted to avert the long-term consequences of obesity.
Evaluating temporal trends of sand drift potential in Southeast arid areas of Iran, Sistan region
Authors: Rahdari Mohammad Reza , Caballero-Calvo Andrés , Kharazmi Rasoul , Rodrigo-Comino Jesús
Published: May 2023

The Sistan region located in Southeastern Iran is one of the most sensitive areas related to sandstorms and wind erosion in the world. It is well-known that one of the most influential factors in sandstorm interpretation is sand drift potential (SDP), which is directly related to wind speed. However, accurate monitoring of this phenomenon are scarce considering different temporal scales. Therefore, the main aim of this research is to analyze the trend of SDP on monthly and annual scales. Our results showed that monthly variations of SDP obtained the highest and lowest values in July (609 VU) and January (47 VU), respectively. Quicksand moved to the southeast, as well as the directional index fluctuated from 0.88 to 0.94. The annually SDP was equal to 2700 VU, which represents a relatively high value compared to other arid regions of the world. The results of trend analysis applying the Mann–Kendall test showed that there is a positive (1987–2001) and negative (2002–2016) trend, but the positive trend is not significant. Furthermore, the results of Sen’s slope test demonstrated that the negative trend could be obtained with a higher slope during July, September, and Au-gust; as well a positive trend could be obtained with a higher slope during November, December, and June. We concluded that land managers and stakeholders that are in charge to control quicksand using biological and physical methods should pay attention to these trends in arid environment to apply nature-based solutions or control strategies focusing on these temporal sequences.
Multilevel mixed effect analysis of adequate postnatal care in Ethiopia: Evidence from EMDHS, 2019
Authors: Ashemo Mubarek Yesse , Shiferaw Desalegn , Biru Bayise , Feyisa Bikila Regassa
Published: May 2023

Background
The postpartum period is critical for both the mother's and newborn child's health and survival. Rising morbidity and mortality are usually the consequence of absence of adequate, suitable, or timely care during that time period. There is lack of information on the adequacy of postnatal care in Ethiopia and this study was aimed to investigate adequacy of postnatal care and its determinants in the study area.
Methods
In this study we used a cross-sectional dataset from the Ethiopia Mini Demographic and Health Surveys conducted in 2019. A multistage stratified clustered design applied and survey weights were used to take into account the complicated sample design. A multilevel mixed effects logistic regression was fitted on 3772 women who were nested within 305 clusters. The fixed effect models were fitted and expressed as adjusted odds ratios with 95% confidence intervals, while intra-class correlation coefficients, median odds ratio, and proportional change in variance explained measures of variation. As model fitness criteria, the deviance information criterion and the Akaike information criterion were used.
Results
This study found that only 563(16.14%, 95% CI: 16.05–16.24) women had adequate post natal care. Age of between 25–35 years old (AOR = 1.55, 95%CI = 1.04–2.31), secondary level of education (AOR = 2.23, 95%CI = 1.43–3.45), Having parity of between two and four had (AOR = 0.62, 95%CI = 0.42 0.93), having ANC follow up four and above (AOR = 1.74, 95%CI = 1.31–2.33), being residents of Oromia region (AOR = 0.10, 95CI = 0.02–0.43) were strong predictors of adequate postnatal care. ()
Conclusion
The study found that prevalence of adequate PNC in Ethiopia was significantly low. To increase postnatal care adequacy, it was recommended to reinforce existing policies and strategies such as increasing number of antenatal care follow up, and scheduling mothers based on the national postnatal care follow-up protocol.
Substrate type and discovery govern decomposition along a savanna rainfall gradient
Authors: Bunney Katherine , Robertson Mark , Eggleton Paul , Archibald Sally , Parr Catherine
Published: May 2023

Decomposition is the process by which dead plant biomass is recycled and made available again for uptake by other plants. It is largely mediated by microbes and soil invertebrates. Global decomposition studies have demonstrated that decomposition is primarily temperature-driven with rainfall playing a secondary role, although to date, all global decomposition studies have used a single substrate to measure decomposition meaning differences with substrate type may be missed. Here we explored the decomposition of wood, dung and grass along a rainfall gradient (380–650 mm/year) at three savanna sites in South Africa. As the three sites experience a similar temperature range, we effectively controlled for temperature allowing us to explore the effect of rainfall in isolation. We used decomposition bags - with and without termite access - and measured mass loss after set time intervals. We predicted that the absolute decomposition of all three substrates would increase along the rainfall gradient. This assumption held for dung and grass, but we found the reverse for wood. Our study highlights the importance of considering multiple substrates as decomposition patterns and dominant agents can vary. Unexpectedly low wood decomposition at our wettest site suggests that the amount of dead wood available, and therefore probability of discovery by termites, may be an important factor explaining findings from decomposition studies. Resource availability and termite discovery is a neglected subject within decomposition studies and warrants further investigation.