bluuebunny/crossref_metadata_2025 huggingface dataset:
Perbandingan Kadar Laktat Antara Propofol-Fentanil dengan Isofluran-Fentanil Pada Operasi Kraniotomi Cedera Otak Sedang;
Authors: Rasyid Harsakti , Tanra Husni , Gaus Syafruddin , P Ilhamjaya
Published: May 2020

Latar Belakang : Cedera otak menimbulkan gangguan beberapa sistem tubuh dan sering menyebabkan iskemia. Laktat terbentuk dari metabolisme anaerob glukosa otak akibat kurangnya oksigen.Tujuan : Membandingkan kadar laktat antara propofol-fentanil dengan isofluran-fentanil pada operasi kraniotomi cedera kepala sedang.Metode : Dilakukan penelitian eksperimental secara acak tersamar tunggal terhadap 42 pasien yang menjalani prosedur kraniotomi cedera kepala sedang. Subyek penelitian dibagi dalam dua kelompok, kelompok pertama mendapat pemeliharaan anestesi propofol 6 mg/kgBB/jam dan fentanil 1 mcg/kgBB/jam (n=21), sementara kelompok kedua mendapat pemeliharaan isofluran 1 vol% dan fentanil 1 mcg/kgBB/jam (n=21). Dilakukan pemeriksaan kadar laktat vena pra bedah, setelah intubasi, setelah kraniotomi, dan setelah ekstubasi. Data diuji berdasarkan Shapiro Wilk, bila distribusi data normal diuji dengan independent T test dan bila distribusi tidak normal dilakukan transformasi data dengan fungsi log. Tingkat kepercayaan 95% dengan kemaknaan p<0,05.Hasil : Hasil penelitian menunjukkan kadar laktat pada pemeliharaan anestesi propofol 6 mg/kgBB/jam dan fentanil 1 mcg/kgBB/jam lebih rendah setelah intubasi, setelah kraniotomi, dan setelah ekstubasi dan secara statistik bermakna (p<0,05) dsbanding pemeliharaan isofluran 1 vol% dan fentanil 1 mcg/kgBB/jam.Kesimpulan : Kadar laktat pada operasi kraniotomi cedera otak sedang dengan pemeliharaan anestesi propofol-fentanil lebih rendah dibanding kadar laktat  dengan pemeliharaan anestesi isofluran-fentanil. Propofol dan fentanil dapat dijadikan pemeliharaan anestesi bedah saraf traumatik.
Angka Kejadian dan Faktor-Faktor yang Mempengaruhi Infeksi Paska Pemasangan Kateter Vena Sentral di Rumah Sakit Dr. Soetomo
Authors: Widiastuti Eka Seprianti , Wahjuprajitno Bambang
Published: May 2020

Latar Belakang : Setiap tahun lebih dari 150 juta kateter intravena digunakan , dimana 5 juta dari mereka dipasang pada vena sentral . Sayangnya , lebih dari 500.000 infeksi yang terkait dengan pemasangan alat secara intravaskular melalui aliran darah terjadi di AS setiap tahun , 7-20 % disebabkan oleh central venous catheter - related blodstream infection ( CR - BSI ) . CR - BSI terkait dengan perpanjangan lama tinggal di rumah sakit , meningkatkan biaya dan kematian. Beberapa faktor yang mempengaruhi terjadinya CR - BSI seperti tempat penyuntikan, prosedur pemasangan yang steril maksimal, dressing transparan, perawatan tanpa teknik aseptik, penggunaan nutrisi parenteral dan inotropikik katekolamin, kondisi pasien , dan banyak lagi. Belum ada data tentang kejadian CR - BSI dan faktor-faktor yang mempengaruhinya di Rumah Sakit Umum Dr Soetomo, .Tujuan : Menghitung angka kejadian CR - BSI dan menganalisis faktor-faktor yang mempengaruhinya di Dr Soetomo Surabaya .Metode : Prosedur penelitian dimulai sejak CVC dipasang pada pasien, data dasar dicatat seperti identitas, kondisi awal, komorbiditas , dan teknik pemasangan. Pasien diikuti untuk mengevaluasi teknik perawatan CVC, pemakaian antibiotik sistemik, penggunaan nutrisi parenteral dan inotropikik katekolamin, serta dugaan CR - BSI. Kultur darah dilakukan bila dicurigai infeksi timbul ( baik secara klinis dan menggunakan Skor IPS), dan kemudian diagnosis CR - BSI dibuat . Semua data dicatat sampai CVC telah dilepas dan pasien keluar dari rumah sakit .Hasil : Ada 15 kasus CR - BSI pada 139 pasien, total durasi pemakaian CVC adalah 1.751 hari, sehingga tingkat CR - BSI 8.57 kasus per 1000 hari penggunaan CVC. Tingkat tertinggi adalah di bangsal neurologi, 35,71 kasus per 1000 hari penggunaan CVC. Lama tinggal di rumah sakit ( p = 0,032 ), durasi penggunaan CVC ( p = 0,002 ), penggunaan nutrisi parenteral ( p = 0,000 ), penggunaan inotropikik katekolamin ( p = 0,041 ), skor APACHE II ( p = 0,000 ), infeksi sebelum pemakaian CVC ( p = 0,039 ) dan infeksi di tempat lain ( p = 0,033 ) merupakan faktor signifikan yang mempengaruhi kejadian CR - BSI . Namun, jika faktor-faktor ini diperiksa bersama-sama, durasi penggunaan CVC ( p = 0,030 ), penggunaan nutrisi parenteral ( p = 0,005 ), dan skor APACHE II ( p = 0,006 ) memberikan pengaruh yang dominan terhadap CR - BSI .Kesimpulan : Angka kejadian CR - BSI di Dr Soetomo Rumah Sakit Umum tinggi, sedangkan durasi CVC digunakan, penggunaan nutrisi parenteral , dan skor APACHE II sebagai faktor paling dominan yang mempengaruhi kejadian infeksi tersebut .
Novel mutations in the CYBB gene causing X-linked chronic granulomatous disease: a case report of 2 patients
Authors: Sud Shama , Grunebaum Eyal , Upton Julia , Kim Vy H.D.
Published: May 2020

Introduction: Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency caused by mutations in the NADPH complex characterized by recurrent infections, inflammation and autoimmunity. While autosomal recessive forms exist, X-linked CGD makes up the majority of cases, which is caused by mutations in the CYBB gene. Patients are at high risk for infections with catalase positive bacteria and fungi. The prognosis has improved significantly with improvements in disease detection and management, including prophylactic antibiotic and antifungal therapy. Hematopoietic stem cell transplantation (HSCT) is a curative option for patients with a suitable donor.

Aim: To report the clinical presentation, immune features and genetic mutations in 2 patients with novel mutations in the CYBB gene causing X-linked CGD who underwent HSCT.

Results: Case 1: Patient 1 is a 14-year-old patient who initially presented with disseminated aspergillosis at the age of 3. He was noted to have an abnormal neutrophil oxidative burst index (NOBI) and genetic testing revealed a mutation in the CYBB gene (c.883_87dupGTGGT) consistent with CGD. He successfully underwent HSCT at age 4. At age 10 he developed a primary intracranial rhabdomyosarcoma in the posterior cranial fossa. Case 2: Patient 2 is a 4-year-old male who was worked up for CGD after developing a perianal abscess at 1 month of age followed by Moraxella bacteremia at 2 months of age. He had 2 abnormal NOBIs and genetic testing identified a novel mutation in the CYBB gene that was thought to explain his phenotype (c.941delA). He underwent an HSCT (10/10 HLA matched unrelated donor). Both patients have had normalization of their NOBI post-transplant and remain free of significant infections.

Discussion: We report the clinical presentation, immune features and genetic mutations in 2 patients with novel mutations in the CYBB gene causing X-linked CGD. Identifying pathogenic mutations causing CGD is important for a better understanding of genotype–phenotype associations and disease course in this patient population.

Statement of novelty: We describe 2 pediatric patients diagnosed with X-linked chronic granulomatous disease due to novel mutations in the CYBB gene.
Somatic outcomes of young people with chronic diseases participating in transition programs: a systematic review
Authors: Becker Johanna , Ravens Esther , Pape Lars , Ernst Gundula
Published: May 2020

Introduction

There is growing evidence that the health of young people with chronic health conditions deteriorates during the transfer from child-centred to adult-oriented health care. Risks include not only the deterioration of health status in general but also the occurrence of secondary diseases and adverse events. Transition programs have been implemented. However, there is a lack of evidence about whether they reduce these risks and which interventions should be principally included. Evidence-based guidelines for the transition of young people should be introduced. In this study we therefore aim to summarise actual evidence on somatic outcomes during the transition period.

Methods

A systematic literature review was conducted. Two independent reviewers searched in electronic databases (Cochrane, Embase, PubMed, Web of Science) for intervention studies that aimed to improve transition. Last update of search was October 31st 2018. Grey literature was also searched. Studies were included if they examined participants aged 11 years or older suffering from a chronic health condition and evaluated interventions aimed to improve somatic outcomes after transition. Controlled trials or studies with a measurement before and after intervention were considered. The certainty of evidence was assessed using the GRADE approach. Additionally, each study was graded using a modified grading scale based on GRADE.

Results

28 studies met the inclusion criteria. Patients suffered from different chronic conditions such as type 1 diabetes, solid organ transplantation, inflammatory bowel disease or cystic fibrosis. Interventions had different components such as transition checklists, workshops, web-based interventions, transition plans, joint visits or transition coordinators. Outcomes included mortality and morbidity. They varied according to chronic condition. Thirteen studies showed beneficial effects in the intervention group or in post-intervention measurements. The certainty of evidence was very low.

Conclusion

A considerable number of studies evaluating transition interventions was identified. Transition interventions had some beneficial effects. Workshops, joint visits and longer or multidisciplinary appointments may be particularly effective components. Transition guidelines could be based on these results. However, due to the limitations of the included studies it is difficult to draw firm conclusions. More research is needed to further evaluate the effectiveness of transition interventions. It should address the deficits identified from prior studies, such as poor study design, short follow-up time or small sample sizes.
Fasted Versus Nonfasted Aerobic Exercise on Body Composition: Considerations for Physique Athletes
Authors: Escalante Guillermo , Barakat Christopher
Published: May 2020

Physique athletes often incorporate aerobic exercise as part of their exercise program to increase caloric expenditure for the purposes of improving their body composition. One method used by some physique competitors is to perform aerobic exercise in the fasted state under the assumption that low glycogen levels after an overnight fast allow for greater mobilization of stored fat to be used for fuel because carbohydrates are not readily available to produce energy. The purpose of this article is to examine the existing literature on the effect of fasted versus fed cardio on improving body composition for physique athletes.
The Forgotten 1979 MoMA Sound Art Exhibition
Authors: Dunaway Judy
Published: May 2020

Over the past 40 years “sound art” has been hailed as a new artistic category in numerous writings, yet one of its first significant exhibitions is mentioned only in passing, if at all. The first instance of the hybrid term sound art used as the title of an exhibition at a major museum was Sound Art at the Museum of Modern Art in New York (MoMA), shown from 25 June to 5 August 1979. Although this was not marketed as a feminist exhibition, curator Barbara London selected three women to exemplify the new form. Maggi Payne created multi-speaker works that utilized space in a sculptural fashion; Connie Beckley combined language and sounding sculptural objects, showing sound in both a conceptual and physical manifestation; and Julia Heyward’s work used aspects of feminist performance art including music, narrative, and the voice in order to buck abstract aesthetics of the time. This paper uses archival research, interviews, and analysis of work presented to reconstruct the exhibition and describe the obstacles both the artists and the curator encountered. The paper further provides context in the lives of the artists and the curator as well as the surrounding artistic scene, and ultimately exposes the discriminatory reasons this important exhibition has been marginalized in the current discourse.
Silent Listening
Authors: Wierzbicki James
Published: May 2020

This essay explores how one “listens to”—that is to say, how one takes in, makes sense of, and reacts to—“sounds” that are not really sounds at all but that are simply evocations of sounds served up by the authors of fiction. Although the essay’s conclusions apply to literary sounds in general, the examples on which the essay bases its observations and arguments are drawn—because their affective range is so very, very wide—from the vintage literature of so-called horror fiction. After a discussion of why some instances of scary literary sounds are more potent than others, emphasis is placed on sounds featured in the work of H. P. Lovecraft and Edgar Allan Poe, writers celebrated for their “aurality” yet whose structural use of sonic imagery—in dynamic patterns in the case of Lovecraft, as markers of plot points in the case of Poe—has hitherto been neglected. Throughout the essay parallels are of course drawn between literary sounds and actual sounds encountered both in the real world and in the fictional worlds of film, television, and radio drama. Readers of the essay are invited to decide for themselves, but it is suggested here that “silent listening”—because it demands creative involvement on the part of its participants—results in a richer aesthetic experience.
Karakterizacija mikroplastike u sedimentu plaže Prapratno
Authors: Erceg Matko , Tutman Pero , Bojanić Varezić Dubravka , Bobanović Anđela
Published: May 2020

Mikroplastika predstavlja ozbiljan problem u morskom i priobalnom okolišu. Analiziran je uzorak mikroplastike iz sedimenta plaže Prapratno na poluotoku Pelješcu, Hrvatska. Uzorkovanje i laboratorijsko odvajanje provedeni su prema DeFishGear protokolu. Svaki ispitak svrstan je u određenu kategoriju te je svakom određena masa, boja, prozirnost, maksimalna dimenzija i površina. Identifikacija je provedena infracrvenom spektroskopijom (FTIR) – HATR tehnikom. Otpad s plaže Prapratno sastoji se uglavnom od polietilena te, u manjem udjelu, od polistirena i polipropilena.
Characteristics of adrenocortical carcinoma in South Korea: a registry-based nationwide survey
Authors: Lim Jung Soo , Lee Seung-Eun , Kim Jung Hee , Kim Jae Hyeon , _ _
Published: May 2020

Purpose

To evaluate the clinical characteristics and prognostic factors in patients with adrenocortical carcinoma (ACC) in South Korea.

Methods

A nationwide, registry-based survey was conducted to identify pathologically proven ACC at 25 tertiary care centers in South Korea between 2000 and 2014. Cox proportional hazard model and log-rank test were adopted for survival analysis.

Results

Two hundred four patients with ACC were identified, with a median follow-up duration of 20 months (IQR 5–52 months). The median age at diagnosis was 51.5 years (IQR 40–65.8 years), and ACC was prevalent in women (n = 110, 53.9%). Abdominal pain was the most common clinical symptom (n = 70, 40.2%), and ENSAT stage 2 was most common (n = 62, 30.4%) at the time of diagnosis. One hundred sixty-nine patients underwent operation, while 17 were treated with other modalities. The remission rate was 48%, and median recurrence-free survival time was 46 months. Estimated 5-year recurrence-free rate was 44.7%. There were more women, large tumor, atypical mitosis, venous invasion, and higher mitotic count in cancer recurrence group. Estimated 5-year overall survival and disease-specific survival rates were 64.5 and 70.6%, respectively. Higher ENSAT stage and advanced pathologic characteristics were risk factors for all-cause mortality of ACC. Large tumor size and cortisol-secreting tumor were additional risk factors for ACC-specific death.

Conclusions

We report the first epidemiologic study regarding ACC in an Asian population. ENSAT stage 4; lymph node involvement; non-operative group; and invasion of vein, sinusoid, or capsule were associated with an increased risk for all-cause mortality.
Adropin inhibited tilapia hepatic glucose output and triglyceride accumulation via AMPK activation
Authors: Zhang Chaoyi , Zhang Qianli , Huang Zhihong , Jiang Quan
Published: May 2020

Adropin plays a role in the maintenance of energy homeostasis, insulin resistance prevention, and impaired glucose tolerance. However, the molecular mechanisms by which adropin affects hepatic glucose and lipid metabolism in vitro are not entirely understood. This study intended to examine the roles and underlying mechanisms of adropin in glucose and lipid metabolism in Nile tilapia. In primary cultured tilapia hepatocytes, adropin significantly attenuated oleic acid (OA)-induced glucose output and reduced the activities and mRNA expression of cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase), which are involved in gluconeogenesis. In contrast, adropin facilitated glucose uptake activity via glucose transporter 1 (Glut1) upregulation in OA-treated hepatocytes. One-week of adropin treatment reduced the hepatic total lipid accumulation in OA-fed tilapia without changes in body weight. Subsequent studies revealed that adropin suppressed OA-induced intracellular triglyceride accumulation and decreased the expression of genes and proteins involved in lipid metabolisms such as sterol regulatory element-binding protein-1c (SREBP-1c), acetyl-CoA carboxylase α (ACCα) and CD36, but upregulated peroxisome proliferator-activated receptor α (PPARα) levels. In parallel studies, however, adropin had no detectable effects on fatty acid-binding protein 4 (Fabp4) and carnitine palmitoyltransferase 1α (Cpt1α) mRNA expression. Furthermore, adropin treatment dose-dependently increased the phosphorylation level of AMP-activated protein kinase (AMPK). Suppression of AMPK by compound C or AMPKα1 siRNA blocked adropin-induced decreases in the mature form of SREBP-1c expression, glucose output, and intracellular triglyceride content in OA-treated hepatocytes. These findings suggest that teleost adropin could suppress hepatic gluconeogenesis and triglyceride accumulation via a mechanism dependent on AMPK signalling.
Intramuscular Myxoma of the Thigh: A Case Report
Authors: Zaizi Abderrahim , Benomar Hicham , Badaoui Reda , Fekhaoui Mohammed Reda , Grimi Talal , Mahfoud Mustapha , Berrada Mohamed S
Published: May 2020

Introduction: Myxomas are rare benign tumors of soft tissue, represent 1% of adult cancers, they are most often located in the intramuscular compartment, particularly in the thigh. They are most often observed in elderly patients between the fifth and seventh decade, particularly females.Case report: We present the case of a 60-year-old man with a painless and several years progressive mass of the medial aspect of the left thigh. Magnetic Resonance Imaging (MRI) has shown a tissue mass with a cystic lesion. In addition, histopathological diagnosis of the specimen was in favor of an intramuscular myxoma without signs of malignancy. Short and long-term follow-up of two years did not detect any recurrence.Conclusion: The slowly growing character is not an argument of benignity, in contrast to other situations. Therefore, the myxoid component may be present in other soft tissue malignant tumors, specially liposarcoma. This difficulty sometimes imposing more specimen verification or a second opinion. Although myxomas are rare, it is important to keep them in mind when a myxoid component is present and distinguish them from sarcomas.
Dios como verdad subjetiva y paradoja en el pensamiento religioso de Soren Kierkegaard
Authors: Bravo Peña Fernando
Published: May 2020

El texto analiza la concepción de Dios considerando dos elementos: Dios como verdad subjetiva y paradoja. Básicamente, Dios como verdad subjetiva significa que la creencia religiosa es un fenómeno personal e interior. La paradoja del Dios cristiano se encarna en la figura de Cristo: ¿cómo puede Dios manifestarse como un ser humano? Por lo tanto, en el cristianismo hay dos caminos: creer en Dios o no creer en Dios. Esta disyuntiva tiene un fundamento en una premisa de Kierkegaard: la creencia en Dios no puede ser racionalizada ni demostrada.

Palabras clave: Dios, verdad subjetiva, paradoja, cristianismo
Cartografía de lo sagrado. Una exploración en la espiritualidad malécu
Authors: Madrigal Víctor
Published: May 2020

La espiritualidad del pueblo malecu conforma una particular visión del mundo, según la cual, sus divinidades Tócu maráma habitan los ríos del territorio ancestral. A la conformación física del territorio le subyace una cartografía sagrada con imbricaciones simbólicas profundas en la manera de comprenderse a sí mismos y de cómo fundamentan el dinamismo de las relaciones sociales, y, en última instancia, cómo se vinculan con la naturaleza y de forma particular con la tierra, lugar de retorno al morir. El subsuelo es espacio de reunión con sus parientes y con todas aquellas personas quienes en vida siguieron las normativas divinas. Palabras clave: Lo sagrado, espiritualidad, pueblos indígenas, territorio
Economic efficiency of Bulgarian dairy synthetic population and Assaf sheep breeds
Authors: Stankov K.
Published: May 2020

Abstract. The economic efficiency of ewes from the Bulgarian dairy synthetic population (BDSP) and Assaf sheep breeds, reared in three production systems, e.g. grazing on pasture, stall-pasture rearing and stall rearing was studied. The results from the study showed that BDSP ewes in the stall-pasture rearing system had a relatively low milk yield for a specialised dairy sheep breed – 80L for the lactation period. In this system, without the subsidy, the profit and cost efficiency were negative, while with subsidy, minimum positive results were achieved. For BDSP ewes reared in a stall-pasture rearing system with stall feeding during the grazing period and grazing on improved pastures, the obtained milk yield was by 33% higher. The subsidy resulted in satisfactory profit and cost efficiency, while without the subsidy, the farm ended in loss. BDSP and Assaf ewes reared in stalls, demonstrated substantially higher milk yield and productivity. They realised a profit and good cost efficiency. The milk yield of BSDP sheep reared in stalls was 200L per lactation, and fertility – 140%. The Assaf breed in which a high level of selection and regulated reproduction cycle was achieved, had 250L milk per lactation and 140% fertility. The profit with subsidy was 128.85 BGN (1Lev=0.975€) and without the subsidy: 48.85 BGN, with relatively high cost efficiency. An introduction of traits for higher milk yield, polyestrus and fertility from Assaf into BSDP sheep is necessary.
Еffect of insect infestation on the economic value of smoked fish sold in selected markets in Nigeria
Authors: Ayeloja A.A. , George F.O.A. , Jimoh W.A. , Adebisi G.L.
Published: May 2020

Abstract. In the present study a multistage sampling technique using semi-structured questionnaire was used to obtain information on socio- economic characteristics of the respondents and on economic loss of smoked fish resulting from insect pest infestation. Smoked fishes were bought from 10 markets in Oyo state, South West of Nigeria and checked in the laboratory for the insect pests. Data were analyzed using descriptive statistics and Chi-square. Results indicated that insects at their larvae stage cause more economic loss to smoked fish than adult insects while Necrobia rufipes and Dermestes spp. are the insects found to infest the smoked fishes in this study. The insect infestation of the smoked fish leads to huge economic loss. Of all respondent groups the women dominate smoked fish business.
A húgyhólyag-recidíva jellemzői felső üregrendszeri daganatos betegekben radikális ureteronephrectomia után
Authors: Kovács Petra Terézia , Juhász Dániel , Módos Orsolya , Kocsmár Ildikó , Terebessy András , Lotz Gábor , Szarvas Tibor , Nyirády Péter , Riesz Péter
Published: May 2020

Absztrakt:

Bevezetés: Urothelium béleli a vesemedencét, a
húgyvezetéket, a húgyhólyagot és a húgycső proximalis harmadát, így ezen
területek bármelyikén kialakulhat átmeneti sejtes carcinoma. A felső
üregrendszeri daganatok ritka elváltozások, jelentőségüket azonban az adja, hogy
a húgyhólyagban gyakori a recidíva, mely kockázatának felmérésére a mai napig
nem alakult ki egységesen elfogadott rizikóbecslés.
Célkitűzés: A felső üregrendszeri
daganatos betegek adatainak általános jellemzése, illetve a
húgyhólyag-recidívára vonatkozó rizikóbecslés.
Módszer: A 2005. január 1. és 2016. december
31. közötti időszakban a Semmelweis Egyetem Urológiai Klinikáján radikális
ureteronephrectomiával kezelt betegek adatainak tanulmányozása, statisztikai
elemzése. Eredmények: Átmeneti sejtes felső
üregrendszeri daganat 135 betegnél igazolódott. A betegeket a műtéttől számítva
átlagosan 32 hónapig (SD: 30,25) követték, ezalatt 31 betegnél (23%) találtak
húgyhólyag-recidívát, átlagosan 19,6 hónap (SD: 29,7) után. Minél idősebb korban
fedezték fel a betegnél a primer daganatot, annál hamarabb észleltek kiújulást a
húgyhólyagban (p = 0,007). A diagnóziskor ismert magas vérnyomás esetén is
szignifikánsan korábban tért vissza az elváltozás (p = 0,035).
Következtetés: A vizsgálat eredményei
alapján az idősebb és multimorbid betegek esetében a daganat hamarabb recidivált
a húgyhólyagban, ezért az ő figyelmüket különösen érdemes felhívni a rendszeres,
cystoscopiát is magában foglaló ellenőrző vizsgálat fontosságára már a kezelés
megkezdésekor. Orv Hetil. 2020; 161(21): 881–888.
A coarctatio aortae kezelése újszülöttkortól a felnőttkorig
Authors: Hartyánszky István , Varga Sándor , Hartyánszky István , Bogáts Gábor
Published: May 2020

Absztrakt:

A veleszületett szívhibák sebészi kezelése a technika fejlődésével folyamatosan
változik. Az egyik legegyszerűbb, legközismertebb fejlődési rendellenesség a
coarctatio aortae. A szerzők az elmúlt évtizedek során alkalmazott műtéti
megoldásokat (’end-to-end’ anasztomózis, foltplasztikák, interpositumok), a
műtéti lehetőségeket mutatják be, hazai és nemzetközi tapasztalatok alapján
ismertetik a különböző megoldások eredményeit, előnyeit, hátrányait. Nagy
sebészi kihívást jelent az újszülöttkori súlyos aorta-hypoplasiával járó
eseteknek, a későbbiekben a kialakuló restenosisoknak és az esetleges
szövődményeknek (aneurysmák, dissectiók) a megoldása. A coarctatio aortae
megoldásai még napjainkban is nehézségeket, sebészi kihívást jelentenek, hiszen
ezeknek mások a megoldásai csecsemőkben és nagyobb gyermekekben, illetve
felnőttkorban. Itt már sokszor kell alkalmazni a katéterintervenciós
megoldásokat is, melyek helyes időzítése még napjainkban is nagy kihívást
jelent. Orv Hetil. 2020; 161(21): 861–866.
Drepanolejeunea pinnatiloba Schiffn. (Lejeuneaceae): a rare species in Brazil rediscovered after 17 years
Authors: Carvalho dos Reis Luciana , Oliveira Hermeson Cassiano de , Pôrto Kátia Cavalcanti
Published: May 2020

Drepanolejeunea pinnatiloba Schiffn. (Lejeuneaceae) has only been collected once in Brazil, from a single population in the Atlantic Forest in southern Bahia state. Seventeen years later, we report the second record of D. pinnatiloba. This new record is from the Una Biological Reserve, also in southern Bahia. We discuss the geographic distribution and evaluate conservation status of this species for Brazil and the Neotropical region.
1622 o la canonización de la Reforma Católica
Authors: Labarga Fermín
Published: May 2020

La canonización de 1622, en que se inscribió en el catálogo de los santos a los beatos Isidro Labrador, Ignacio de Loyola, Francisco Javier, Teresa de Jesús y Felipe Neri, fue memorable por diversas razones. Su gestación no fue sencilla. Paulo v había decidido canonizar al beato Isidro labrador, lo que asumió también su sucesor, Gregorio xv. Las fuertes presiones a las que fue sometido tanto por los monarcas católicos como por las órdenes a las que pertenecían los nuevos santos, especialmente los jesuitas, determinaron a corto plazo su canonización conjunta, agregándose primero la beata Teresa, luego Ignacio de Loyola y Francisco Javier y, finalmente, con el fin de evitar una ceremonia exclusivamente española, a instancias de la propia Congregación, el beato Felipe Neri. Sin negar el componente político de la canonización, en el presente artículo se ofrecen otras líneas de interpretación convergentes con el fin de demostrar que la de 1622 fue no sólo la canonización de los protagonistas de la Reforma Católica sino, simbólicamente, de la propia Reforma de la Iglesia en si misma.
Stress and quality of sleep in undergraduate nursing students
Authors: Silva Kézia Katiane Medeiros da , Martino Milva Maria Figueiredo de , Bezerra Clarissa Maria Bandeira , Souza Ângela Monic Lima de , Silva Danila Maria da , Nunes Jacqueline Targino
Published: May 2020

ABSTRACT Objective: to analyze the level of stress and sleep quality in nursing students according to terms of the nursing program. Method: descriptive and cross-sectional research developed in a higher education institution in Northeastern Brazil on 167 students. We used data collection, sociodemographic information, and a scale for assessing stress and sleep quality in nursing students. Results: we identified a statistically significant difference between domains of the stress scale and the terms of the undergraduate program, and between the quality of sleep and such terms such as as in the fourth and sixth semesters. Conclusion: different stress scores show that the semester which concerns students the most is the fifth. Quality of sleep was deemed good for the first, third, fifth, seventh, and eighth semesters; and poor for the fourth and sixth terms.
Expert assessment of the “Neonatal Pain Assessment Program” online course
Authors: Silva Fernanda Felipe Ferreira da , Costa Taine , Peres Heloisa Helena Ciqueto , Duarte Elysângela Dittz , Castral Thaíla Correa , Bueno Mariana
Published: May 2020

ABSTRACT Objectives: to assess layout quality, visual identity and content of the “Neonatal Pain Assessment Program” (Programa de Avaliação da Dor Neonatal) online course. Methods: a descriptive exploratory study. The course was assessed by 24 experts in pain, neonatology and education. A form containing 20 questions on technical, interface and educational aspects was used. For each item, the score ranged from 0 to 1. Mean scores above 0.7 were considered indicative of high quality of the items. Descriptive statistics were used for data analysis. Results: navigation, clarity, ease of localization, content relevance, contextualization, content correction, multiple windows, ease of use, ease of return, ergonomics, esthetics, special brands, audiovisual resources, information and portability were assessed. All aspects obtained a mean ≥ 0.70 and no changes were required. Conclusions: the Neonatal Pain Assessment Program is considered as quality educational technology and promising strategy for health education.
Sheltered adolescents’ background of exposure to violence and distressful experiences
Authors: Ramos Kézia Áurea de Almeida , Rafael Ricardo de Mattos Russo , Penna Lucia Helena Garcia , Depret Davi Gomes , Ribeiro Liana Viana , Carinhanha Joana Iabrudi
Published: May 2020

ABSTRACT Objectives: to analyze the exposure to violence and distressful experiences lived by adolescents in institutional shelters in the city of Rio de Janeiro (previous to their admittance). Methods: a cross-sectional study carried out in public institutional shelter units, with a sample of 72 adolescents aged between 12 and 18 years. Data on sociodemographic aspects, family relationships and distressful experiences were obtained by means of the Parcours Amoureux des Jeunes instrument, validated for use in Brazil. Statistical analysis included estimates of prevalence and 95% confidence intervals. Results: high magnitudes of distressful experiences and overlapping abuses lived by adolescents were observed, especially violent events (72.2%), social exclusion (59.1%), and sexual harassment (48.6%). Conclusions: the study shows that adolescents under institutional sheltering come from a background of severe and frequent distressful experiences. These took place in multiple environments: family (prior to their institutional reception), community, and group.
Perception of professionals about patient safety in psychosocial care
Authors: Souza Adrielle Cristina Silva , Bezerra Ana Lúcia Queiroz , Caixeta Camila Cardoso , Pinho Eurides Santos , Paranaguá Thatianny Tanferri de Brito , Teixeira Cristiane Chagas
Published: May 2020

ABSTRACT Objective: To understand the professionals’ perception of risks and factors related to patient safety incidents in psychosocial care. Methods: Descriptive-exploratory study, with a qualitative approach, carried out with 31 professionals in type III Psychosocial Health Care Centers, between October 2016 and April 2017. Data collection was mediated by the Experiential Learning Cycle. Content analysis was performed. Results: The professionals revealed risks and factors related to safety incidents in their daily practices, associated with the institution’s physical and organizational structure, with the configuration of the clinical process, with clinical administration and organizational management. Final considerations: Continuous efforts are needed on the part of senior managers and professionals to improve the work process and organizational structure in psychosocial care, contributing to the development of the patient’s autonomy and social rehabilitation, avoiding institutionalization and, especially, ensuring the safety of this type of care.
Militancy of nurses in the institutionality field: printed media versions
Authors: Laitano Aline Di Carla , Silva Gilberto Tadeu Reis da , Almeida Deybson Borba de , Padilha Maria Itayra , Peres Maria Angélica de Almeida , Santos Victor Porfírio Ferreira Almeida
Published: May 2020

ABSTRACT Objectives: to analyze nurses’ professional militancy in the institutionality field, presented by the printed media from Bahia State in the 1970s and 1980s. Methods: a historical and qualitative research under Social History’s perspective, whose data source was the newspaper A Tarde. The temporal cut-off encompasses milestones such as professional body restructuring and creation. Results: the Associação Brasileira de Enfermagem democratization movement was reported in a superficial way, highlighting the struggle for power spaces. With respect to Conselhos Federal e Regional de Enfermagem daBahia, the newspaper notified creation and function of bodies, however, there was no visibility to the newspaper’s performance. Concerning the union, there was political fragility of nurses against the creation and union participation in the fight for labor rights. Final Considerations: organization of political action occurred from isolated groups mobilization of professionals who were already traveling in political spaces, not the large mass of professionals.
Authentic leadership among nursing professionals: knowledge and profile
Authors: Mondini Cleide Carolina da Silva Demoro , Cunha Isabel Cristina Kowal Olm , Trettene Armando dos Santos , Fontes Cassiana Mendes Bertoncello , Bachega Maria Irene , Cintra Flávia Maria Ravagnani
Published: May 2020

ABSTRACT Objectives: to identify the knowledge of nursing professionals about leadership models and evaluate the authentic leadership profile among them. Methods: analytical study, conducted between August and December 2015, involving 84 nursing professionals working in a public and tertiary hospital. We used two instruments: Sociodemographic Questionnaire with questions about leadership and the Authentic Leadership Questionnaire. Results: both nurses and nursing technicians were unaware of authentic leadership. Both pointed to communication, planning, and organization as competencies of the leader (n = 58, 95%). Regarding the authentic leadership profile, we observed that the score was “high” among nurses and “low” among technicians. Holding a leadership position and professionally upgrading has positively influenced the highest-profile of authentic leadership. Conclusions: nurses demonstrated to know behavioral leadership, while nursing technicians showed knowledge about situational leadership. Nurses had a high score of authentic leadership behaviors, while nursing technicians had a low score, but we found no significant difference between them. Holding a leadership position and professionally upgrading has positively influenced the highest profile of authentic leadership.
Construction and validation of an educational video for human papillomavirus vaccination
Authors: Interaminense Iris Nayara da Conceição Souza , Oliveira Sheyla Costa de , Linhares Francisca Márcia Pereira , Guedes Tatiane Gomes , Ramos Vânia Pinheiro , Pontes Cleide Maria
Published: May 2020

ABSTRACT Objectives: to validate an educational video aimed at the adhesion of human papillomavirus vaccination. Methods: a methodological study, where the knowledge about the theme and the technology to be constructed in six focal groups was identified; a theoretical framework was set up and the existing videos were uploaded. After that, pre-production, production and post-production were followed. In validation of content, 22 specialists participated, and in appearance, ten adolescents, ten mothers, ten teachers and ten audiovisual professionals. Absolute frequency, Binomial Test, and Content Validity Index were used. Results: agreement was satisfactory in most items. Regarding relevance, 20 items had indices above 0.80 among judges. Assessment was positive among girls and mothers. Only three items had indices less than 0.80 among teachers and video professionals. Conclusions: the educational video was validated, conferring credibility to contribute to educational actions and improve vaccination indexes.
Validation of the definitions of nursing diagnoses for individuals with Aids
Authors: Souza Neto Vinicius Lino de , Costa Rayanne Teresa da Silva , Santos Wenysson Noleto dos , Fernandes Sâmara Fontes , Lima Dhyanine Morais de , Silva Richardson Augusto Rosendo da
Published: May 2020

ABSTRACT Objectives: to develop and validate conceptual and operational definitions of nursing diagnoses of the International Classification for Nursing Practice for people living with Aids. Methods: methodological study with 100 individuals with Aids, in a hospital school. In addition, 19 nurses selected from the Lattes platform acted as experts in the validation process. The research was conducted, using three moments: identification and validation of the nursing diagnoses; construction of the conceptual and operational definitions of the diagnoses, and content validation, using the content validity index. Results: a total of 35 diagnoses were identified and 18 had their conceptual and operational definitions validated, with validity index of ≥ 0.8. Conclusions: the construction of the conceptual and operational definitions enables nurses to analyze the clinical inferences and endorse the nursing diagnosis, contributing to its predictive capacity.
LAW AND MORAL JUSTIFICATION
Authors: Faggion Andrea
Published: May 2020

ABSTRACT Many prominent legal philosophers believe that law makes some type of moral claim in virtue of its nature. Although the law is not an intelligent agent, the attribution of a claim to law does not need to be as mysterious as some theorists believe. It means that law-making and law- applying acts are intelligible only in the light of a certain presupposition, even if a lawmaker or a law-applier subjectively disbelieves the content of that presupposition. In this paper, I aim to clarify what type of moral claim would be suitable for law if law were to make a claim to be morally justified. I then argue that legal practice is perfectly intelligible without moral presuppositions - that is, that the law does not necessarily make moral claims.
ARE NECESSARY IDENTITIES EVER DISBELIEVED?
Authors: Maunu Ari
Published: May 2020

ABSTRACT The purpose of this paper is to bring out, by means of a simple thought experiment involving demonstratives, a discrepancy between what is expressed and what is believed (which contradicts the Theory of Direct Reference), and to consider some consequences of this - most notably, whether we might hold, for example, that the ancients never believed that Hesperus is not Phosphorus.
SEIN UND ZEIT: LA LIBERTAD DEL DASEIN PARA SER-LIBRE COMO MISMIDAD. ANÁLISIS FENOMENOLÓGICO DE LA LIBERTAD Y LA MISMIDAD EN EL § 44
Authors: Periñán Juan José Garrido
Published: May 2020

RESUMEN Este artículo de investigación intenta tematizar la mismidad del Dasein dentro de los límites intrínsecos del § 44 de Ser y Tiempo, en conexión plena con el existenciario verdad de la existencia, a fin de entender esta mismidad como un fenómeno eminente y ontológico de libertad. Tal derivación, en dirección a la libertad, mostrará que la conexión Dasein-Verdad solo puede ser realizada mediante un desarrollo de la mismidad del Dasein, entendida como un fenómeno relacionado con el “poner/quedar en libertad” y el “ser-libre”. Este será, en último término, el objetivo de este artículo de investigación
ONTOLOGIA E CIÊNCIA NA CRÍTICA DE NIETZSCHE À METAFÍSICA EM HUMANO, DEMASIADO HUMANO
Authors: Mattioli William
Published: May 2020

RESUMO Neste artigo, discuto o que considero serem os pressupostos ontológicos da crítica de Nietzsche à metafísica no primeiro livro de Humano, demasiado humano e a natureza da relação estabelecida por ele entre filosofia e ciência. Busco definir sua posição como um realismo científico moderado, que considera que as ciências caminham progressivamente em direção a uma concepção puramente dinâmica do real.
The trauma and acute care surgeon in the COVID-19 pandemic era
Authors: RIBEIRO JUNIOR MARCELO AUGUSTO FONTENELLE , DE-CAMPOS TERCIO , LIMA DANIEL SOUZA , MARTTOS-JR ANTONIO C , PEREIRA BRUNO M
Published: May 2020

ABSTRACT The World Health Organization recognized in March 2020 the existence of a pandemic for the new coronavirus that appeared in China, in late 2019, and whose disease was named COVID-19. In this context, the SBAIT (Brazilian Society of Integrated Care for Traumatized Patients) conducted a survey with 219 trauma and emergency surgeons regarding the availability of personal protective equipment (PPE) and the role of the surgeon in this pandemic by means of an electronic survey. It was observed that surgeons have been acting under inadequate conditions, with a lack of basic supplies as well as more specific equipment such as N95 masks and facial shields for the care of potential victims who may be contaminated. The latter increases the risk of contamination of professionals, resulting in potential losses in the working teams. Immediate measures must be taken to guarantee access to safety equipment throughout the country, since all trauma victims and/or patients with emergency surgical conditions must be treated as potential carriers of COVID-19.
Hiatal hernia repair: prevention of mesh erosion and migration into the esophagogastric junction
Authors: BRAGHETTO Italo , KORN Owen , ROJAS Jorge , VALLADARES Hector , FIGUEROA Manuel
Published: May 2020

ABSTRACT Background: Erosion and migration into the esophagogastric lumen after laparoscopic hiatal hernia repair with mesh placement has been published. Aim: To present surgical maneuvers that seek to diminish the risk of this complication. Method: We suggest mobilizing the hernia sac from the mediastinum and taking it down to the abdominal position with its blood supply intact in order to rotate it behind and around the abdominal esophagus. The purpose is to cover the on-lay mesh placed in “U” fashion to reinforce the crus suture. Results: We have performed laparoscopic hiatal hernia repair in 173 patients (total group). Early postoperative complications were observed in 35 patients (27.1%) and one patient died (0.7%) due to a massive lung thromboembolism. One hundred twenty-nine patients were followed-up for a mean of 41+28months. Mesh placement was performed in 79 of these patients. The remnant sac was rotated behind the esophagus in order to cover the mesh surface. In this group, late complications were observed in five patients (2.9%). We have not observed mesh erosion or migration to the esophagogastric lumen. Conclusion: The proposed technique should be useful for preventing erosion and migration into the esophagus.
Música, redes e tecnologia na periferia: impactos tecnológicos na produção de rap na zona sul de São Paulo
Authors: Michel Rodrigo Cavalcante , Machado Ana Flávia , Sátyro Natália Guimarães Duarte
Published: May 2020

Resumo O paradigma tecnológico das TICS trouxe mudanças signiﬁ cativas na economia da música, reduzindo custos e ampliando possibilidades de acesso à produção. O objetivo do presente artigo é veriﬁcar se os atuais impactos tecnológicos na produção de música também são percebidos em zonas periféricas urbanas, a partir do estudo de caso da produção de música rap no Grajaú. Assim, considera-se a hipótese: os impactos tecnológicos possibilitaram redução nos custos de produção e ampliação do acesso à produção musical. Ademais, novas formas organizacionais de produção emergem baseadas em redes. Os resultados encontrados resumem-se em: a) os impactos das TICs na produção musical veriﬁcam-se no estudo de caso especíﬁ co, sugerindo que as inovações atingem também a periferia; b) a produção de música local ocorre em organizações baseadas em redes, incorporando relações monetárias e comunitárias. Nota-se que a produção de música rap no Grajaú apresenta aspectos comunitários e colaborativos associados a econômicos e monetários.
O impacto de choques no setor cultural brasileiro: uma análise de emprego e renda à luz dos cortes orçamentários
Authors: Silva Marcus Vinícius Amaral e , Brito Danyella Juliana Martins de
Published: May 2020

Resumo As recentes mudanças nas políticas públicas voltadas à cultura brasileira, como a perda do status de ministério e as alterações na Lei de Incentivo à Cultura, vêm suscitando uma série de questionamentos quanto a importância do setor para a economia. Neste contexto, este artigo analisa como uma redução no consumo de bens e serviços do setor cultural impacta na produção, no rendimento e no emprego do próprio setor e das demais atividades econômicas. Para tal, emprega-se como metodologia o modelo de insumo-produto, para dados de 2015. Os resultados demonstram que os efeitos do choque proposto são percebidos em diversos setores da economia, em especial para aqueles fornecedores diretos de insumos para o setor cultural. Adicionalmente, há uma importante redução nos postos de trabalho e no rendimento das famílias, não contida apenas no setor cultural, mas propagada para toda a economia.
Risk factors related to seropositivity for Leptospira spp. in horses in the Serra Catarinense region
Authors: Farias Deise Keli , Dick Gabriela , Bunn Silvério , Thaler Neto André , Rech Carolina , Menin Álvaro , Saito Mere Erika
Published: May 2020

ABSTRACT: Leptospirosis is a zoonotic infectious disease caused by the bacterium Leptospira spp. The consequences of infection in horses are unclear, and the serogroups involved vary depending on the region. This study aimed to evaluate the seropositivity of unvaccinated horses in the Serra Catarinense region and the possible risk factors associated with the infection. We used 207 horses from 26 properties, with no clinical history of infection and unvaccinated for leptospirosis. We submitted serum samples to the microscopic agglutination serum (SAM) to obtain the main reference serogroups. We considered animals with titre ≥100 as infected. The results of the serology revealed seropositivity in 45.4% (94/207) of the animals studied. The most frequent antibodies reportedwere those against the serogroups Australis 16.9% (35/207), Ichterhaemorrhagiae 14.4% (30/207), and Grippotyphosa 5.31% (11/207). Among the primary risk factors associated with the infection we reported extensive rearing system (OR = 1.27; P<0.05) and the presence of other animal species such as cattle (OR = 3.85; P<0.01) and capybaras (OR = 2.07; P=0.06). The findings presented in this study showed that leptospirosis is endemic in horses in the Serra Catarinense region, and revealed the need for emergency surveillance and control measures specific to this important zoonosis.