bluuebunny/crossref_metadata_2025 huggingface dataset:
Storia recente. La costruzione di un campo di studio in Argentina
Authors: Alonso Fabiana
Published: February 2024

All'indomani della caduta delle dittature militari nel Cono Sud dell'America Latina e nel quadro della transizione alla democrazia, la preoccupazione per i diritti umani e le memorie della repressione hanno fatto emergere diversi conflitti sul significato da attribuire al passato recente. Concentrandosi sul caso argentino, l'articolo affronta i principali temi delle politiche della memoria e del dibattito intellettuale sugli anni Settanta. Il testo affronta gli esordi, lo sviluppo e l'articolazione interna di un campo di studio denominato "storia recente".
Il centenario pop. Quando un anniversario diventa (anche) prodotto commerciale
Authors: Tonelli Anna
Published: February 2024

Il centenario del Pci ha generato la pubblicazione di numerosi volumi di storiografia, ma ancora di più ha coinvolto la produzione giornalistica con inserti monografici, la copiosa memorialistica e strumenti multimediali. Nella maggioranza dei casi la chiave di lettura è all'insegna della nostalgia e del "come eravamo" oppure una ricostruzione del passato con gli occhi del presente, soprattutto per sottolineare l'eterna divisione della sinistra.
Exploring Canadian Legal Policies and its Impact on the Status Acquisition Process of Stateless Individuals in Canada
Authors: Lee Seo Young
Published: February 2024

Over ten million of the world's population live without nationality. Canada reproduces stateless individuals by failing to protect stateless individuals from Canada and the individuals who arrived in Canada without nationality from the country of origin due to the limitations of the laws. Canada introduced status acquisition pathways that grant legal status by considering unusual hardship and exceptional cases, but these incorporate limitations of the Canadian legal practices. The required identification documents, long processing time, expensive application fees and legal procedures based on discretionary power make it impossible to protect stateless individuals. The three legal instruments, the Citizenship Act subsections 5(4), 5(5) and the Immigration and Refugee Protection Act subsection 25(1), may reproduce statelessness. Therefore, it is necessary to understand the legal aspects and move beyond the legal aspects when implementing and exercising policies as they directly affect the daily lives of stateless individuals.
Older Immigrants’ Mental Health: A Narrative Review
Authors: Jama Muna
Published: February 2024

This narrative review explores the mental health of older immigrants in Canada through an intersectional lens which was informed by Arksey and O’Malley’s methodological framework for conducting a scoping review. Research shows that because of the immigration process, older immigrants experience mental health issues such as depression, anxiety and posttraumatic stress disorder. As Canada’s older immigrant population grows, it is critical that the mental health of older immigrants is investigated. This narrative review addresses the following research question: what is known from the existing literature about the mental health of older immigrants in Canada? The following 4 themes emerged from the 15 articles included in this narrative review: social isolation and loneliness, family and social support, the social determinants of mental health and barriers to accessing mental health services. This narrative review’s results include policy recommendations aimed at improving the mental health of older immigrants and areas for future research.
Political Capital, the COVID-19 Pandemic, and Pathways to Permanent Residency for Low-Skilled Migrant Workers: A Bourdieusian Perspective
Authors: Cuthbertson Hayley
Published: February 2024

The COVID-19 pandemic has had a swift and dramatic impact on every aspect of Canadian life. This paper explores how the socio-economic effects of the COVID-19 pandemic have altered the positionality of low-skilled migrant workers in the Canadian immigration regime and labour market. Using Pierre Bourdieu’s sociological framework and concept of political capital, this paper seeks to explain how low-skilled migrant workers temporarily benefited from the distinction they received as essential workers during the pandemic in the form of new, albeit temporary, pathways to permanent residency. The designation of “essential” provided to low-skilled migrants and the distinction that accompanied it allowed them to experience an increased accumulation of political capital and redistribution of influential power. This paper will examine the Temporary Residency to Permanent Residency Pathway and Guardian Angel Program as examples of the fluctuations in Immigrant, Refugees and Citizenship in Canada’s practices during the pandemic and as temporary public policy responses to the increase in political capital accumulated by low-skilled migrant workers.
What’s Skill Got to do With it? Labour Market and Immigration Experiences of Skilled Temporary Foreign Workers
Authors: Berman Rachel
Published: February 2024

This paper presents the findings from a qualitative constructivist grounded theory study that incorporates the perspectives of skilled migrant workers and employers who hire them, from across Canada. The study explores workplace relationships and experiences, as well as how both migrant workers and employers navigate the immigration system. While there has been significant critique of policies and programs that limit migrant worker mobility, these studies tend to focus on lower-skilled workers, leaving higher skilled workers who do not have permanent immigration status out of the discussion. These are workers who may be working on closed or open work permits, often for several years before qualifying for permanent residence. The experiences that temporary workers transitioning to permanent residence go through are broken down into four processes: Finding a “good” job, navigating bureaucracy, negotiating power in the workplace, and becoming a permanent resident.
LGBTQ+ Claimants and the Refugee Determination Process in Canada
Authors: Ameh Lawrencia
Published: February 2024

Horrific human rights violations have forced many Lesbian, Gay, Bisexual, Transgender, Queer/Questioning (LGBTQ+) people to seek refuge in countries like Canada with stronger human rights laws and protection. Canada, in particular, has an international reputation for being a ‘welcoming’ nation and a ‘safe’ haven for refugee claimants. However, this paper reveals that LGBTQ+ persons seeking asylum in Canada based on their sexual orientation and gender identity/expression (SOGIE), experience distinct challenges in navigating the determination process, especially in relation to their mental health and safety. One of the most harmful aspects of the refugee determination process for LGBTQ+ refugee claimants is the need to ‘prove’ one’s sexual orientation and gender identity / expression. This paper thus provides recommendations for re-evaluating testimony and evidence based on fear of persecution, not on ‘proving’ the sexual orientation or gender identity / expression of claimants.
Why Choose Canada?: A Critical Internet Discourse Analysis on Canadian and Korean Perspectives of ‘Value’ in Canadian Higher Education
Authors: Tobin Kimberley
Published: February 2024

This Major Research Paper examines why Korean international students are choosing to study abroad in Canada, through a critical internet discourse analysis of educational marketing material via the internet space. By critically evaluating online educational marketing material from websites, blogs, online forums and other internet mediums, this paper examines how Korean international students are seeking specific cosmopolitan elements within higher education that challenge traditionally upheld western narratives. This paper further explores how these specific elements are being propagated within the internet space, suggesting a shift within the global imaginary regarding the ‘value’ of higher education and studying abroad.
The Professional Integration of International Medical Graduates: Implications of Restricted Certificates During the COVID-19 Pandemic
Authors: Taki Saeid
Published: February 2024

The Covid-19 emergency conditions and the call to practice for international medical graduates (IMG) has put a spotlight on their certification challenges. This study aimed at examining the root cause of the bottleneck in the certification process by analyzing the pertinent policies including the restricted certificate issued during the pandemic. The representation of the issue in the media discourse during the early months in 2020 was also studied. To this end, the Foucauldian approach to policy and discourse analysis was adopted. The results revealed that with the governance system at work any measure such as the restricted certificate would be only short-lived. The voices echoed in the discourse around the challenges also lent support to the policy analysis results, reiterating the malfunctioning of the certification system. However, the exceptional conditions created during the pandemic can be regarded as a turning point when we try to rebuild post-COVID opportunities for internationally-educated healthcare professionals.
Development and Validation of an Instrument to Assess Activism towards Environmental and Social Sustainability in Career Counseling
Authors: Ginevra Maria Cristina , Di Maggio Ilaria , Santilli Sara , Nota Laura
Published: February 2024

Considering the recent attention to challenges regarding sustainability even within career issues, this study is aimed at providing the development and initial validation of the instrument “Thoughts, Feelings, and Actions about Whatever Does not go as It Should” (TFA) which may be used in career counseling and research activities to assess activism towards environmental and social sustainability in career guidance. With this aim, two different studies were carried out. In the first study, after having developed items and having examined content validity, the factorial structure and the reliability of the instrument was tested. The second study tested the discriminant validity with measures of career adaptability, propensity to sustainability in taking decisions about one’s future, and life satisfaction. Results showed good psychometric support for the TFA instrument for the Italian population. Moreover, the results obtained showed as the total score and the sub-factors score of TFA are related but distinct from the constructs considered, suggesting that workers with higher levels of these dimensions are characterized by greater career adaptability, propensity to sustainability in taking decisions about own future, and life satisfaction.
Community of Inquiry: Designing Quality Online Instruction for Special Educator Preparation
Authors: Jackson Haidee , Yang Sohyun
Published: February 2024

Online education programs are on the rise and institutions of higher learning are utilizing Learning Management Systems (LMS) to facilitate online learning. The Community of Inquiry (CoI; Garrison et al., 1999) framework identifies three categories of cognitive presence, social presence, and teaching presence to guide the development of online instruction and has been adopted by numerous institutions of higher learning. This article identifies instructional strategies conducive to the design of online presence using the CoI framework to ensure quality learning experiences in online special educator preparation programs. We address some of the features of LMS system tools present in Canvas that are utilized by instructors when designing and implementing online instruction to include: communications, modules and assignments, collaboration, and grading.
Mineralni sastav plodova borovnica
Authors: Duralija Boris , Konjević Nikolina
Published: February 2024

Početkom 21. stoljeća borovnice zbog svojih nutritivnih svojstava plodova postaju popularne među potrošačima, a što povećava njihovu potražnju. Kultivirane borovnice stoga zauzimaju sve veći značaj kako u svjetskoj tako i u hrvatskoj proizvodnji voća. Mineralni sastav plodova je važna komponenta koja utječe na kvalitetu plodova i njihovu nutritivnu vrijednost. U ovom radu napravljen je prikaz mineralnog sastava plodova borovnice, kao i nutritivne vrijednosti. Na temelju proučene literature utvrđeno je kako su u plodovima borovnice najzastupljeniji makroelementi dušik i kalij dok su kod mikroelemenata to mangan i željezo. Obrađeni su i najvažniji čimbenici koji imaju utjecaj na mineralni sastav borovnica, kao što su: sorta, klima, tlo, agrotehnički i pomotehnički zahvati. Odabirom i upravljanjem navedenih čimbenika moguće je povećati kvalitetu ploda, ali i utjecati na mineralni sastav plodova borovnica.
Efecto de la especificidad de la carga en el día previo a la competición en ciclistas Masters de Montaña. Un estudio piloto
Authors: Rodríguez Redondo David , Barrera Domínguez Francisco , Romero Lorencio Juan Manuel , Sánchez Nosea Isabel , Ortiz Domínguez Rodolfo , Vázquez Lorente Héctor , Molina Lopez Jorge
Published: February 2024

Objetivo: El presente estudio pretendió evaluar el efecto la especificidad del estímulo de activación en el día previo a la competición sobre el rendimiento deportivo en ciclistas Máster de MTB.

Métodos: El presente estudio se trata de un diseño prospectivo, longitudinal y cuasi experimental llevado a cabo con 6 participantes varones (edad, 44.0±6.63 años; peso, 70.7±8.32 kg; VO2 máx., 60.8±9.92 ml/kg/min) que realizaron 3 diferentes tipos de activaciones (0, situación control; 1, una situación específica encima de la bici; 2, situación inespecífica fuera de la bici realizada mediante el ejercicio de fuerza con cargas individualizadas en base al perfil fuerza-velocidad). El rendimiento de los ciclistas fue evaluado mediante un test de 5 minutos all-out a máxima intensidad.

Resultados: Los principales resultados mostraron diferencias significativas para la cadencia media en la situación 0 vs 2 (p=0.018, d=1.740) y frecuencia cardíaca media en 0 vs 1 (p=0.002, d=3.347). Además, la eficiencia (potencia/pulso) resultó ser estadísticamente significativa entre situaciones 0 vs 1 (p=0.05) y con tendencia a la significación en 1 vs 2 (p=0.082). Específicamente, se observó un mayor incremento de la FC y producción de potencia en los primeros 120s del test en situación control frente a las situaciones intervenidas (p<0.05).

Conclusiones: Las tres situaciones de activación propuestas obtuvieron un rendimiento general similar en todos los parámetros medidos, aunque la propuesta de activación especifica parece ser beneficiosa para la mejora del rendimiento en competición en ciclistas máster de MTB. Se requieren más investigaciones al respecto.
METODE PENDIDIKAN BELA NEGARA BADAN KESATUAN BANGSA DAN POLITIK KOTA BANDUNG DALAM MEMBANGUN GENERASI MUDA YANG TANGGUH
Authors: Setiawan Mursyid , Ramdhani Hilal
Published: February 2024

Metode pendidikan bela negara yang dilakukan oleh Badan Kesatuan Bangsa dan Politik (Bakesbangpol) Kota Bandung sangat penting dalam memperbaiki dengan generasi muda yang menunjukkan adanya penurunan sikap nasionalisme, serta merubahnya menjadi generasi muda yang tangguh. Tujuan penelitian ini adalah untuk menganalisis metode pendidikan bela negara yang dilakukan oleh Bakesbangpol Kota Bandung dalam mewujudkan generasi muda yang tangguh dan menghadapi berbagai ancaman yang dihadapi oleh generasi muda akibat adanya globalisasi. Teori yang digunakan yaitu teori metode pendidikan, pertahanan keamanan negara dan konsepsi bela negara. Analisis ini menggunakan metodologi kualitatif dengan pendekatan studi kasus, dengan strategi pengumpulan data melalui wawancara, observasi, dan dokumentasi. Penemuan telah menunjukkan pendidikan bela negara dari Bakesbangpol Kota Bandung diselenggarakan dengan menggunakan model pentahelix. Keunggulan dari metode pendidikan bela negara yang dilaksanakan oleh Bakesbangpol Kota Bandung yaitu mengembangkan generasi muda yang tangguh dengan memiliki dimensi geografis, psikologis, security, dan dedikasi, sedangkan kelemahannya yaitu belum adanya metode tindak lanjut dan media bagi generasi muda dalam menjalin komunikasi
PERAN NYATA PUSAT HIDRO-OSEANOGRAFI TNI ANGKATAN LAUT DALAM PENANGGULANGAN BENCANA
Authors: Kristiyono Kristiyono , Maarif Syamsul , Madjid M Adnan
Published: February 2024

Pusat Hidro-Oseanografi TNI Angkatan Laut (Pushidrosal) bertugas untuk melaksanakan pembinaan hidro-oseanografi dalam rangka mendukung kepentingan TNI maupun kepentingan sipil, serta menyiapkan data dan informasi wilayah pertahanan di laut dalam rangka mendukung tugas pokok TNI Angkatan Laut. Undang-Undang No. 34 tahun 2004 tentang TNI menyebutkan bahwa tugas pokok operasi militer selain perang diantaranya adalah membantu menanggulangi akibat bencana alam, pengungsian, dan pemberian bantuan kemanusiaan, membantu pencarian dan pertolongan dalam kecelakaan (search and rescue). Dengan demikian, Pushidrosal juga mengemban fungsi untuk penanggulangan bencana, baik bencana alam, bencana non alam, dan membantu pencarian dan pertolongan dalam kecelakaan (search and rescue). Pushidrosal memiliki kemampuan dalam bidang hidrografi dan oseanografi yang dapat dimanfaatkan untuk membantu penanggulangan bencana, namun belum banyak diketahui dan dimanfaatkan oleh instansi terkait dalam membantu penanggulangan bencana di Indonesia. Penelitian ini untuk menganalisis peran Pushidrosal dalam penanggulangan bencana di Indonesia. Penelitian ini menggunakan metode kualitatif deskriptif, yaitu menggambarkan bagaimana Pushidrosal dalam penanggulangan bencana. Hasil penelitian menunjukkan bahwa Pushidrosal telah berperan nyata dan aktif dalam melaksanakan penanggulangan bencana yaitu dengan melaksanakan survei investigasi untuk keselamatam navigasi kecelakaan transportasi di laut dan survei investigasi untuk bencana alam seperti gempa bumi dan tsunami. Pushidrosal juga sudah melaksanakan survei untuk mengetahui penyebab tsunami seperti yang telah dilaksanakan di Palu dan Banten. Peta laut yang diproduksi oleh Pushidrosal selain digunakan untuk keselamatan navigasi kapal dari bencana kecelakaan transportasi juga sebagai upaya mitigasi bencana kegagalan teknologi yang ditimbulkan oleh pipa bawah laut. Pushdirosal juga aktif dalam melaksanakan pencarian dan penyelamatan seperti kejadian jatuhya pesawat Air Asia QZ8501 diperairan Pangkalan Bun Kalimantan Tengah tahun 2014, pesawat Lion Air JT-610 diperairan Karawang Jawa Barat tahun 2018, tenggelamnya KM Sinar Bangun di Danau Toba Sumatera Utara tahun 2018, serta yang terakhir pesawat Sriwijaya Air SJ-182 di teluk Jakarta tahun 2021.
PEMELIHARAAN SATUAN TEMBAK PELURU KENDALI STARSTREAK GUNA MENDUKUNG KESIAPAN OPERASI PERTAHANAN UDARA
Authors: Kristianto Dian , Priyanto Priyanto , Prakoso Lukman Yudho
Published: February 2024

The world has experienced a very rapid development of air power technology such as aircraft, missiles, drones, bringing the consequences of the emergence of an air attack threat from one country to another. Indonesia as one of the countries is likely to experience the threat of air attacks from other countries that can endanger national security and territorial sovereignty so that Indonesia needs a strong and resilient air defence. In addition to aircraft as the main element of air defence, there is a ground-to-air missile weapon system, one of which is the Starstreak missile currently owned by the Army Air Defence Artillery unit which is incorporated in the Starstreak missile firing unit in each unit. The weapon system can be operationalised if it is in good condition and ready for operation, so a good maintenance activity is needed and in accordance with procedures. The purpose of the study was to analyse the maintenance of the Starstreak missile firing unit in the Arhanud 8/MBC Battalion to support the implementation of air defence operations that are the responsibility of the unit. The type of research used is descriptive qualitative with a phenomenological approach, using the IITCA theory (Integrative, Interactive, Transparency, Controlling, Accountability). Data were obtained from informants who were determined and then analysed with qualitative analysis techniques. The results showed that the implementation of maintenance of the Starstreak missile firing unit was not in accordance with the provisions or procedures so that there was still damage that occurred proving that maintenance had not been carried out optimally
STRATEGI KOMPI ZENI NUBIKA ANGKATAN DARAT MENGHADAPI PANDEMI COVID-19
Authors: Rizki Nur , Gumilar Nugraha , Edhie Iroth Sonny
Published: February 2024

Ancaman pandemi dan wabah penyakit berbahaya dan mematikan sangat mungkin terjadi di Indonesia. Penyebaran Covid-19 yang tidak terkendali dan melebihi kapasitas epidemi, menjadikan status penyebaran Covid-19 sebagai wabah pandemi. Perusahaan Pusziad CBRNE merupakan lembaga pelaksana tingkat pusat di bidang CBRNE. Ancaman biologis semakin meningkat dan menyebar, seperti dalam penanganan pandemi Covid-19, Perusahaan Pusziad CBRNE mempunyai keterbatasan. Kemampuan Perusahaan Pusziad CBRNE belum mencukupi dari aspek organisasi, sumber daya personel dan peralatan. Penelitian ini menganalisis bagaimana strategi Perusahaan Pusziad CBRNE dalam menghadapi pandemi Covid-19 dengan penelitian kualitatif dan pengumpulan data melalui observasi, wawancara dan dokumentasi. Terjadinya pandemi Covid-19 yang melanda dunia, termasuk di Indonesia dengan angka kematian yang cukup tinggi, merupakan bukti nyata adanya ancaman biologis. Ancaman hayati di Indonesia semakin nyata dengan berkembangnya biosains dan fasilitas pendukungnya di Indonesia serta terbukanya tindakan bioterorisme. Dengan meningkatnya ancaman biologis seperti pandemi Covid-19, peran Perusahaan Pusziad CBRNE menjadi sangat penting. Menghadapi keterbatasan Kompi Pusziad CBRNE maka strategi yang perlu disarankan adalah mengkaji ulang organisasi Kompi Pusziad CBRNE untuk ditingkatkan menjadi Detasemen atau Batalyon, mengusulkan dukungan anggaran yang optimal, memperlengkapi peralatan khusus CBRNE dan meningkatkan kapasitas sumber daya manusia Pusziad. Personel Perusahaan CBRNE. Oleh karena itu, di tengah meningkatnya persepsi terhadap ancaman biologis di Indonesia, Perusahaan Pusziad CBRNE perlu melakukan pembenahan organisasi, kemampuan personel dan peralatan, agar Perusahaan Pusziad CBRNE mempunyai kemampuan yang handal yang didukung oleh organisasi yang proporsional dengan personel yang profesional dan peralatan yang canggih
PENGAMANAN BIG DATA PADA OPERASI INFORMASI DALAM RANGKA MENINGKATKAN PERTUMBUHAN EKONOMI DIGITAL
Authors: Hidayat Andy Nur , Bastari Bastari , Kustiawan Bambang
Published: February 2024

This paper describes the analysis of security vulnerabilities in the national defense system, especially in the cyber sector, related to the revision of PP 82 of 2012 concerning the Implementation of Electronic Systems and Transactions (PSTE) to PP 71 of 2019. The polemic arising from the revision is the change in the rules for placing data centers or big data infrastructure that originally had to be placed in the territory of the Republic of Indonesia has become a recommendation only. Thus, there are new opportunities for state actors or not state actors to use them as intentions and additional possible ways of acting to attack Indonesian defense. The analysis is carried out by means of a literature study and interviews with relevant stakeholders to obtain the latest data and factual information. From this study, it was found that the security gap due to the change in PP 82 of 2001 to PP 71 of 2019 must be anticipated properly, state sovereignty over the data of its citizens is reduced so that cooperation is needed to anticipate these changes between all stakeholders in Indonesia. Furthermore, the rules for placing data centers can be reviewed so that data problems in cyber warfare can be anticipated properly by the TNI
SATUAN PEMELIHARAAN 220th AIRLIFT WING DAN MODERNISASI ANGKATAN BERSENJATA FILIPINA
Authors: Salazar Limuel G , Bastari Bastari , Suseto Buddy
Published: February 2024

In the ever-changing global security landscape, the Philippines is dedicated to modernizing its Armed Forces (AFP). The 220th Airlift Wing, a crucial component of the Philippine Air Force, plays a vital role in air mobility operations. However, the Wing faces challenges in maintaining optimal operational readiness, particularly in intermediate level maintenance capabilities. This research aims to develop strategies to strengthen intermediate level maintenance within the Wing, enhancing operational readiness to support the AFP effectively. A comprehensive approach based on the DOTMPLF framework is proposed to address the issues. The study's findings will provide valuable insights to improve aircraft maintenance, bolster operational readiness, and support the Philippines' defense and socio-economic endeavors. Furthermore, the study uses a qualitative method with descriptive analysis as its methodology. Collecting data will be through field research, enabling direct information gathering from the source. Additionally, formal interviews and desk research utilizing internet resources will be conducted and employed. In conclusion, the further development of the intermediate level maintenance is needed to improve operational readiness of the 220th Airlift Wing. This will result in benefits not only for the PAF but to the whole Filipino nation as well.
THE ROLE OF AMS IN ENHANCING REGIONAL DEFENSE AND SECURITY FOR ASEAN AS "EPICENTRUM OF GROWTH"
Authors: Sutanto Rudy , Priyanto Priyanto
Published: February 2024

Artikel ini menggali peran penting Negara-negara Anggota ASEAN (AMS) dalam meningkatkan pertahanan dan keamanan regional, yang pada akhirnya menempatkan ASEAN sebagai “Episentrum Pertumbuhan.” Tujuan utama penelitian ini adalah untuk mengeksplorasi dan memahami peran AMS dalam meningkatkan pertahanan dan keamanan regional di kawasan ASEAN. Metodologi penelitian menggunakan pendekatan kualitatif, yang menggabungkan data primer dari wawancara dan survei dengan pemangku kepentingan utama dan data sekunder dari tinjauan literatur. Analisis tematik dan konten digunakan untuk mendapatkan wawasan tentang peran AMS dalam meningkatkan pertahanan dan keamanan regional. Artikel ini mengeksplorasi peran penting AMS dalam menjaga keamanan dan stabilitas regional, menekankan pembangunan kepercayaan, konektivitas, diplomasi, dan kolaborasi dengan organisasi regional. Laporan ini menggali mekanisme penyelesaian sengketa di ASEAN dan komitmen kawasan terhadap diplomasi preventif. Lebih jauh lagi, artikel ini membahas tantangan-tantangan yang ditimbulkan oleh kejahatan terorganisir transnasional, dan upaya kolaboratif AMS untuk melawan ancaman-ancaman tersebut. Terakhir, artikel ini membahas keamanan lingkungan, menekankan komitmen ASEAN terhadap pembangunan berkelanjutan, energi terbarukan, dan konservasi laut. Kesimpulannya, keterlibatan proaktif AMS dalam dinamika pertahanan dan keamanan memperkuat peran ASEAN sebagai “Episentrum Pertumbuhan.” Komitmen mereka terhadap stabilitas regional, penyelesaian perselisihan, melawan ancaman transnasional, dan kelestarian lingkungan menempatkan ASEAN sebagai mercusuar perdamaian, kemakmuran, dan ketahanan di kawasan Asia-Pasifik
Sitting Volleyball Learning Model: A Study On Disabled Student Aged 10– 12 Years In Indonesıan Context
Authors: YONO Topo , HUMAİD Hidayat , SAMSUDİN Samsudin
Published: February 2024

This study aims to produce a volleyball learning model for disabled students aged 10-12 years by developing a model that is easily adapted to the physical form. This research is a type of development research used the Borg and Gall model. The subjects of this study are disabled students aged 10 – 12 of 7 specific or exclusive elementary schools grades 4, 5, and 6. Developing or validating model products in the field for physically disabled students is the product of this study. Evaluation by experts using two physical education experts and one learning expert, furthermore we conducted small-scale trials involving questionnaires, consultations, and evaluations. The development results show that the sitting volleyball game learning model is suitable for use and the t test results show that Sig 0,001 < 0.05. These results show that the volleyball model training method is effective in improving the physical fitness of disabled students when compared to conventional training. The conclusion obtained in this research is that the sitting volleyball for disabled students aged 10-12 years is a model that is easily adapted to the physical movement form of students with special needs.
Immunomodulatory Pathogen Recognition Receptor Ligands for Bone Regeneration
Authors:   , Khokhani Paree Kishor
Published: February 2024

Autologous bone grafting stands as the prevailing solution for addressing critical defects, despite its associated drawbacks such as prolonged operation times and safety concerns. In contrast, while convenient, commercially available off-the-shelf bone substitutes often fall short of achieving the efficacy of autografts. Recognizing this gap, this thesis explores a novel approach: replacing killed bacteria with synthetic bacterial cell wall components, known as pathogen recognition receptor (PRR) ligands, to enhance the performance of bone substitutes.

To elucidate the potential of PRR ligands, comprehensive in vitro studies were undertaken. These studies investigated the effects of PRR ligands on human-derived mesenchymal stromal cells and monocytes, shedding light on their ability to modulate the immune response and potentially stimulate osteogenesis. Notably, nucleic acid-based PRR ligands, including CpG ODN C and Poly(I:C), emerged as promising candidates for their capacity to promote osteogenesis through immunomodulation.

Transitioning from in vitro to in vivo experimentation, an investigation was conducted using ovariectomized rats with closed femur fractures. Local injection of PRR ligands at the fracture site was expected to facilitate early inflammation resolution and accelerate fracture healing. However, contrary to expectations, the results of this study failed to demonstrate significant effects on either early inflammation or fracture healing outcomes. Despite this setback, further research efforts were directed towards mimicking the response of killed bacteria through the combination of PRR ligands. Although these attempts yielded promising results, they only partially replicated the beneficial effects observed with killed S. aureus.

In conclusion, the exploration of proinflammatory agents as enhancers of bone formation represents a high-risk, high-reward endeavor. While the potential benefits are substantial, the risks that come with caution and thorough evaluation are also important. Moreover, the complexities of the immune system's response to bone injuries underscore the importance of advancing in vitro and in vivo models to screen and validate osteo-immunomodulatory strategies effectively.

Future research endeavors should prioritize the development of sophisticated experimental models capable of faithfully replicating the intricate interplay between immune responses and bone regeneration. By harnessing the potential of PRR ligands and other innovative approaches, the field stands poised to revolutionize the treatment landscape for bone defects and fractures, offering renewed hope for patients grappling with these challenging conditions.
Improving the evidence base for diagnosis and management of cutaneous leishmaniasis
Authors:   , van Henten Saskia Caroline
Published: February 2024

Cutaneous leishmaniasis (CL) is an infectious skin disease causing chronic lesions which can lead to significant psychosocial harm. In Ethiopia, most patients are diagnosed with microscopy on a painful skin sample, which also misses a substantial number of cases. No uniform treatment practices exist, making it hard to recommend certain regimens. We showed that less-invasive methods to collect a skin sample are just as good, but less painful than the routinely used tools when using PCR. We tried the only available rapid test for CL in Ethiopia, but unfortunately, it detected only around 30% of all cases. We documented routine treatment practices for CL in Ethiopia, and showed that many patients need multiple months of treatment and outcomes are poor. Additionally, drug shortages were common and there were insufficient beds to treat all patients. Miltefosine, a drug in tablet form which could be given outside of the hospital was tried for the first time in Ethiopia. Skin lesions rapidly improved, but the effects of treatment were not sustained, with only around 50% of patients cured after six months. We also tried to treat patients with miltefosine and cryotherapy in a highly endemic village in Ethiopia. There also, only around half the patients were cured. These results indicate that there are no clear cut solutions that can be implemented to improve diagnosis and treatment for CL in Ethiopia. Due to diagnostic uncertainty , poor treatment outcomes and a non-fatal disease, it is vital that doctors carefully weigh the harms and benefits before initiating treatment.
PUTUSAN HAKIM PENGADILAN AGAMA SURABAYA TENTANG WASIAT WAJIBAH BAGI SUAMI NON MUSLIM PERSPEKTIF HUKUM ISLAM
Authors: Wijaya Oming Ratna
Published: February 2024

This research highlights the requirements for valid heirs, where both must be Muslim, but in practice, there are cases where non-Muslims can receive or give inheritance through a Wajibah Will, as happened at the Surabaya Religious Court in case number 0124/pdt.P /2022/PA.Surabaya. The aim of this research is to examine the legality of this decision in law and to look at the provisions that support this decision and the basis of Islamic law that underlies this decision. Field research methods with a qualitative approach were used in this research. Data was obtained from secondary and primary data sources, with data collection techniques in the form of observation, interviews and documentation obtained from information and facts regarding the determination of mandatory wills for non-Muslim husbands at the Surabaya Religious Court. Interviews were conducted with the chairman of the Panel of Judges who determined the case. All data were analyzed inductively. The results of the research show the view of Islamic law from the perspective of the Maliki and Hanafi schools which prohibits Wajibah Wills for non-Muslim husbands. However, the views of the Shafi'i and Ahmad ibn Hanbal schools of thought allow it on condition that it meets the established criteria. Regarding the decision of the Panel of Judges in case number 0124/pdt.P/2022/PA.Surabaya, it is based on the Principle of Equality in the Eyes of the Law, which allows this determination to be made by the panel of judges at the Surabaya Religious Court.
ANALISIS ETIKA BISNIS BERDASARKAN PEMIKIRAN AL-IMAM GHAZALI: STUDI KASUS PADA PERUSAHAAN MINIRAL WATER DAN MBS BAKERY
Authors: Majduddin Mohammad
Published: February 2024

This research aims to investigate the implementation of business ethics in Mineral Water Companies by referring to the principles that emerged in the thoughts of Al-Imam Ghazali. The case study method is used to gain an in-depth understanding of the business practices, policies and values adopted by the company. The research subjects involved mineral water companies and MBS Bakery, selected based on their good reputation in business practices and commitment to ethical values. Data was collected through interviews, observation and document analysis. Data analysis was carried out qualitatively with a thematic and comparative approach. The research results show that the Mineral Water Company consistently applies the principles of business ethics, including honesty, justice and social responsibility. The implications of this research show that the application of business ethics can be a strategic force to improve company performance, increase consumer trust, and strengthen the company's image regarding environmental sustainability. Recommendations include improved employee training programs, marketing strategies more focused on ethical values, and increased environmental sustainability efforts. Thus, this research not only provides in-depth insight into the business practices of Mineral Water Company but also confirms the importance of business ethics in achieving long-term sustainable success.
A review of advanced hydrogels for cartilage tissue engineering
Authors: Ansari Mojtaba , Darvishi Ahmad , Sabzevari Alireza
Published: February 2024

With the increase in weight and age of the population, the consumption of tobacco, inappropriate foods, and the reduction of sports activities in recent years, bone and joint diseases such as osteoarthritis (OA) have become more common in the world. From the past until now, various treatment strategies (e.g., microfracture treatment, Autologous Chondrocyte Implantation (ACI), and Mosaicplasty) have been investigated and studied for the prevention and treatment of this disease. However, these methods face problems such as being invasive, not fully repairing the tissue, and damaging the surrounding tissues. Tissue engineering, including cartilage tissue engineering, is one of the minimally invasive, innovative, and effective methods for the treatment and regeneration of damaged cartilage, which has attracted the attention of scientists in the fields of medicine and biomaterials engineering in the past several years. Hydrogels of different types with diverse properties have become desirable candidates for engineering and treating cartilage tissue. They can cover most of the shortcomings of other treatment methods and cause the least secondary damage to the patient. Besides using hydrogels as an ideal strategy, new drug delivery and treatment methods, such as targeted drug delivery and treatment through mechanical signaling, have been studied as interesting strategies. In this study, we review and discuss various types of hydrogels, biomaterials used for hydrogel manufacturing, cartilage-targeting drug delivery, and mechanosignaling as modern strategies for cartilage treatment.
Decreasing acid value of fatty acid ethyl ester products using complex enzymes
Authors: Li Yuting , Guo Jingjing , Sun Shangde
Published: February 2024

Recently, enzymatic method has been used to prepare biodiesel using various oils. But the high acid value of the biodiesel product using enzyme as a catalyst has been one issue. In this work, an attempt to reduce the acid value of fatty acid ethyl ester (FAEE) product to satisfy the specified requirement (AV ≤ 0.5 mgKOH/g), a complex enzyme-catalyzed method was used for the ethanolysis of Semen Abutili seed oil (SASO) (AV = 5.5 ± 0.3 mgKOH/g). The effects of various variables (constituents of complex enzyme, type and addition of water removal agent, time, temperature, enzyme addition load, substrate ratio) on the enzymatic reaction were investigated. The optimal reaction conditions were: 1% addition of liquid lipase Eversa® Transform 2.0% and 0.8% of enzyme dry powder CALB, reaction temperature 35°C, alcohol-oil ratio 9:1 (mol/mol), 0.8 g/g of 4A-MS and reaction time 24 h. Under the optimal reaction conditions, the FAEE yield was 90.8% ± 1.5% and its acid value was decreased from 12.0 ± 0.2 mgKOH/g to 0.39 ± 0.10 mgKOH/g. In further evaluating the feasibility of preparing FAEE from SASO, the FAEE products obtained under the optimal reaction conditions were purified and evaluated with reference to the ASTM D6751 standard for the main physicochemical indexes. The results obtained were in accordance with the requirements except for the oxidative stability.
The role of Tetraspanins in digestive system tumor development: update and emerging evidence
Authors: Shao Shijie , Bu Zhen , Xiang Jinghua , Liu Jiachen , Tan Rui , Sun Han , Hu Yuanwen , Wang Yimin
Published: February 2024

Digestive system malignancies, including cancers of the esophagus, pancreas, stomach, liver, and colorectum, are the leading causes of cancer-related deaths worldwide due to their high morbidity and poor prognosis. The lack of effective early diagnosis methods is a significant factor contributing to the poor prognosis for these malignancies. Tetraspanins (Tspans) are a superfamily of 4-transmembrane proteins (TM4SF), classified as low-molecular-weight glycoproteins, with 33 Tspan family members identified in humans to date. They interact with other membrane proteins or TM4SF members to form a functional platform on the cytoplasmic membrane called Tspan-enriched microdomain and serve multiple functions including cell adhesion, migration, propagation and signal transduction. In this review, we summarize the various roles of Tspans in the progression of digestive system tumors and the underlying molecular mechanisms in recent years. Generally, the expression of CD9, CD151, Tspan1, Tspan5, Tspan8, Tspan12, Tspan15, and Tspan31 are upregulated, facilitating the migration and invasion of digestive system cancer cells. Conversely, Tspan7, CD82, CD63, Tspan7, and Tspan9 are downregulated, suppressing digestive system tumor cell metastasis. Furthermore, the connection between Tspans and the metastasis of malignant bone tumors is reviewed. We also summarize the potential role of Tspans as novel immunotherapy targets and as an approach to overcome drug resistance. Finally, we discuss the potential clinical value and therapeutic targets of Tspans in the treatments of digestive system malignancies and provide some guidance for future research.
The whole is larger than the sum of its parts: additive effects of SMS nudge bundles
Authors: Barbosa Sergio , Bermúdez Juan Pablo
Published: February 2024

Public access to housing is a challenge for a large number of societies and follows a great number of limitations. Here, we test several SMS-interventions aiming at motivating people to get information on affordable loans for housing options actually available to them. We randomly assigned 6,247 people to receive an SMS inviting them to get information about government backed housing loans for which they were already eligible. SMSs followed one of 14 possible nudges including “simple” nudges (e.g., messages personalized with the recipient's name or mentioning a social norm) and “bundled” nudges (combining personalization with another simple nudge). We observed SMS response rates (i.e., responding to sign up for receiving more information) according to which nudge was assigned. No other independent variable was considered. While most nudges were more effective than a control SMS, we observed significant variation across nudges on their ability to elicit responses from users. Combinations of multiple nudges were more successful in behavior elicitation than simple nudges. We discuss the possible implications of “single” or “bundled” SMS on response rates and as an effective tool of behavior change.
Convergent approach to persistent atrial fibrillation ablation: long-term single-centre safety and efficacy
Authors: Carpenter Alexander , Pannell Laura M. K. , Rizvi Syed I. A. , Maciver Kirsty , Rajakaruna Cha , Ciulli Franco , Duncan Edward R. , Thomas Glyn , Barman Palash , Bond Richard , Nisbet Ashley M.
Published: February 2024

Background

Efforts to maintain sinus rhythm in patients with persistent atrial fibrillation (PsAF) remain challenging, with suboptimal long-term outcomes.

Methods

All patients undergoing convergent PsAF ablation at our centre were retrospectively analysed. The Atricure Epi-Sense® system was used to perform surgical radiofrequency ablation of the LA posterior wall followed by endocardial ablation.

Results

A total of 24 patients underwent convergent PsAF ablation, and 21 (84%) of them were male with a median age of 63. Twelve (50%) patients were obese. In total, 71% of patients had a severely dilated left atrium, and the majority (63%) had preserved left ventricular function. All were longstanding persistent. Eighteen (75%) patients had an AF duration of >2 years. There were no endocardial procedure complications. At 36 months, all patients were alive with no new stroke/transient ischaemic attack (TIA). Freedom from documented AF at 3, 6, 12, 18, 24, and 36 months was 83%, 78%, 74%, 74%, 74%, and 61%, respectively. There were no major surgical complications, with five minor complications recorded comprising minor wound infection, pericarditic pain, and hernia.

Conclusions

Our data suggest that convergent AF ablation is effective with excellent immediate and long-term safety outcomes in a real-world cohort of patients with a significant duration of AF and evidence of established atrial remodelling. Convergent AF ablation appears to offer a safe and effective option for those who are unlikely to benefit from existing therapeutic strategies for maintaining sinus rhythm, and further evaluation of this exciting technique is warranted. Our cohort is unique within the published literature both in terms of length of follow-up and very low rate of adverse events.
Sarcopenia, sarcopenic obesity, and arterial stiffness among older adults
Authors: Fantin Francesco , Giani Anna , Manzato Gisella , Zampieri Annachiara , Comellato Gabriele , Urbani Silvia , Zoico Elena , Mazzali Gloria , Zamboni Mauro
Published: February 2024

Background

Aging is associated with a higher prevalence of sarcopenia, sarcopenic obesity (SO), and increased arterial stiffening, with possible detrimental effects on morbidity and mortality. The aim of this study was to assess the relationships between sarcopenia, SO, and different indexes of arterial stiffness in older adults.

Methods

A total of 77 hospitalized patients (mean age 78.68 ± 9.65 years) were evaluated, obtaining anthropometric variables, biochemical samples, handgrip test, and body composition assessment. Arterial stiffness was evaluated by measuring both carotid-femoral pulse wave velocity (cfPWV), a proxy for central stiffness, and cardio-ankle vascular index (CAVI), as well as considering peripheral arteries. The population was sorted into four subgroups: obese, sarcopenic, SO, and controls.

Results

The highest CAVI (11.31 ± 2.58) was found in sarcopenic patients. SO had the highest value of cfPWV (15.18 ± 8.44 m/s), even after adjustment for significant covariates. In multiple regressions, SO diagnosis resulted as a significant predictor of cfPWV (p = 0.03, R2 = 0.20), and sarcopenia diagnosis resulted as a predictor of CAVI (p = 0.042, R2 = 0.12).

Conclusions

In conclusion, a positive correlation is found between sarcopenia, SO, and arterial stiffness among older subjects. In particular, greater central arterial stiffness is associated with SO, outlining a remarkable effect on the cardiovascular risk profile.