bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental Cross-Species Transmission of Rat Hepatitis E Virus to Rhesus and Cynomolgus Monkeys
Authors: Yang Fengmei , Li Yanyan , Li Yongjie , Jin Weihua , Duan Suqin , Xu Hongjie , Zhao Yuan , He Zhanlong , Ami Yasushi , Suzaki Yuriko , Doan Yen Hai , Takeda Naokazu , Zhang Wenjing , Muramatsu Masamichi , Li Tian-Cheng
Published: January 2022

Rat hepatitis E virus (rat HEV) was first identified in wild rats and was classified as the species Orthohepevirus C in the genera Orthohepevirus, which is genetically different from the genotypes HEV-1 to HEV-8, which are classified as the species Orthohepevirus A. Although recent reports suggest that rat HEV transmits to humans and causes hepatitis, the infectivity of rat HEV to non-human primates such as cynomolgus and rhesus monkeys remains controversial. To investigate whether rat HEV infects non-human primates, we inoculated one cynomolgus monkey and five rhesus monkeys with a V-105 strain of rat HEV via an intravenous injection. Although no significant elevation of alanine aminotransferase (ALT) was observed, rat HEV RNA was detected in fecal specimens, and seroconversion was observed in all six monkeys. The partial nucleotide sequences of the rat HEV recovered from the rat HEV-infected monkeys were identical to those of the V-105 strain, indicating that the infection was caused by the rat HEV. The rat HEV recovered from the cynomolgus and rhesus monkeys successfully infected both nude and Sprague-Dawley rats. The entire rat HEV genome recovered from nude rats was identical to that of the V-105 strain, suggesting that the rat HEV replicates in monkeys and infectious viruses were released into the fecal specimens. These results demonstrated that cynomolgus and rhesus monkeys are susceptible to rat HEV, and they indicate the possibility of a zoonotic infection of rat HEV. Cynomolgus and rhesus monkeys might be useful as animal models for vaccine development.
Acknowledgment to Reviewers of Vaccines in 2021
Authors:   Vaccines Editorial Office
Published: January 2022

Rigorous peer-reviews are the basis of high-quality academic publishing [...]
Behavioural Determinants of COVID-19-Vaccine Acceptance in Rural Areas of Six Lower- and Middle-Income Countries
Authors: Davis Thomas P. , Yimam Adugna Kebede , Kalam Md Abul , Tolossa Asrat Dibaba , Kanwagi Robert , Bauler Sarah , Kulathungam Loria , Larson Heidi
Published: January 2022

Delayed acceptance or refusal of COVID-19 vaccines may increase and prolong the threat to global public health and the economy. Identifying behavioural determinants is considered a critical step in explaining and addressing the barriers of vaccine refusal. This study aimed to identify the behavioural determinants of COVID-19-vaccine acceptance and provide recommendations to design actionable interventions to increase uptake of the COVID-19 vaccine in six lower- and middle-income countries. Taking into consideration the health belief model and the theory of reasoned action, a barrier analysis approach was employed to examine twelve potential behavioural determinants of vaccine acceptance in Bangladesh, India, Myanmar, Kenya, the Democratic Republic of the Congo (DRC), and Tanzania. In all six countries, at least 45 interviews with those who intended to get the vaccine (“Acceptors”) and another 45 or more interviews with those who did not (“Non-acceptors”) were conducted, totalling 542 interviews. Data analysis was performed to find statistically significant (p < 0.05) differences between Acceptors and Non-acceptors of COVID-19 vaccines and to identify which beliefs were most highly associated with acceptance and non-acceptance of vaccination based on the estimated relative risk. The analysis showed that perceived social norms, perceived positive and negative consequences, perceived risk, perceived severity, trust, perceived safety, and expected access to COVID-19 vaccines had the highest associations with COVID-19-vaccine acceptance in Bangladesh, Kenya, Tanzania, and the DRC. Additional behavioural determinants found to be significant in Myanmar and India were perceived self-efficacy, trust in COVID-19 information provided by leaders, perceived divine will, and perceived action efficacy of the COVID-19 vaccines. Many of the determinants were found to be significant, and their level of significance varied from country to country. National and local plans should include messages and activities that address the behavioural determinants found in this study to significantly increase the uptake of COVID-19 vaccines across these countries.
Coccidiosis: Recent Progress in Host Immunity and Alternatives to Antibiotic Strategies
Authors: Lee Youngsub , Lu Mingmin , Lillehoj Hyun S.
Published: January 2022

Coccidiosis is an avian intestinal disease caused by several distinct species of Eimeria parasites that damage the host’s intestinal system, resulting in poor nutrition absorption, reduced growth, and often death. Increasing evidence from recent studies indicates that immune-based strategies such as the use of recombinant vaccines and various dietary immunomodulating feed additives can improve host defense against intracellular parasitism and reduce intestinal damage due to inflammatory responses induced by parasites. Therefore, a comprehensive understanding of the complex interactions between the host immune system, gut microbiota, enteroendocrine system, and parasites that contribute to the outcome of coccidiosis is necessary to develop logical strategies to control coccidiosis in the post-antibiotic era. Most important for vaccine development is the need to understand the protective role of the local intestinal immune response and the identification of various effector molecules which mediate anti-coccidial activity against intracellular parasites. This review summarizes the current understanding of the host immune response to coccidiosis in poultry and discusses various non-antibiotic strategies which are being developed for coccidiosis control. A better understanding of the basic immunobiology of pertinent host–parasite interactions in avian coccidiosis will facilitate the development of effective anti-Eimeria strategies to mitigate the negative effects of coccidiosis.
Novel Treatment Approaches to Combat Trichomoniasis, a Neglected and Sexually Transmitted Infection Caused by Trichomonas vaginalis: Translational Perspectives
Authors: Rigo Graziela Vargas , Frank Luiza Abrahão , Galego Giulia Bongiorni , Santos André Luis Souza dos , Tasca Tiana
Published: January 2022

The multistep translational science behind new drugs comprehends the entire process through laboratory, clinical, and community observations turned into health interventions. The development of new drug options from discovering targets and leading compounds in basic research for implementing therapeutic guidelines contributes to the emergence of health policies essential for infection control. This review updates the translational research in the scenario of the most common non-viral sexually transmitted infection (STI), trichomoniasis. Paradoxically to its high occurrence, it is considered neglected since notification is not mandatory. It turns into a stable disease with health complications, and receives little emphasis from public health programs to control STI. Although related to curable STIs, the current drugs, metronidazole and tinidazole, present therapeutic failures. The need for new options to treat trichomoniasis is established by basic research studies and patents revealing novel synthetic compounds and natural products presenting anti-Trichomonas vaginalis activities, mainly based on in vitro findings. Clinical trials are still focused on new routes of administration for conventional drugs. In addition, nanotechnology approaches are in their infancy, shedding light on potential possibilities for creating more effective, targeted, and safe delivery systems. Overall, the novel proposed approaches need, in addition to pharmaceutical development and efficacy assessments, to ensure that the quality requirements for their use as medicines are met. It is essential to overcome these issues to cross the “Death Valley” of drug discovery and to advance in the translational science criteria in the trichomoniasis drug development field.
Multimodal Treatment of a Canine Lingual Melanoma Using a Combination of Immunotherapy and a Tyrosine Kinase Inhibitors
Authors: Berry Alexander , Hayes Alison , Schiavo Luca , Dobson Jane
Published: January 2022

A 9-year-old female neutered Miniature Schnauzer was diagnosed with a lingual malignant melanoma on the basis of incisional biopsy and histopathology. The patient was initially given a guarded prognosis of a few months’ survival as surgical treatment options were declined by the owner. In order to control the disease a combination treatment of immunotherapy and tyrosine kinase inhibitors was initiated. The mass showed a marked and sustained reduction in size, whilst preserving quality of life for the patient, with a survival at the time of writing of 15 months since diagnosis. This experience suggests that combination therapy for oral malignant melanoma using immunotherapy and tyrosine kinase inhibitors may be successful in some patients and warrants further investigation.
Local Community Composition Drives Avian Borrelia burgdorferi Infection and Tick Infestation
Authors: Lilly Marie , Amaya-Mejia Wilmer , Pavan Lucas , Peng Ceili , Crews Arielle , Tran Nghia , Sehgal Ravinder , Swei Andrea
Published: January 2022

Globally, zoonotic vector-borne diseases are on the rise and understanding their complex transmission cycles is pertinent to mitigating disease risk. In North America, Lyme disease is the most commonly reported vector-borne disease and is caused by transmission of Borrelia burgdorferi sensu lato (s.l.) from Ixodes spp. ticks to a diverse group of vertebrate hosts. Small mammal reservoir hosts are primarily responsible for maintenance of B. burgdorferi s.l. across the United States. Nevertheless, birds can also be parasitized by ticks and are capable of infection with B. burgdorferi s.l. but their role in B. burgdorferi s.l. transmission dynamics is understudied. Birds could be important in both the maintenance and spread of B. burgdorferi s.l. and ticks because of their high mobility and shared habitat with important mammalian reservoir hosts. This study aims to better understand the role of avian hosts in tick-borne zoonotic disease transmission cycles in the western United States. We surveyed birds, mammals, and ticks at nine sites in northern California for B. burgdorferi s.l. infection and collected data on other metrics of host community composition such as abundance and diversity of birds, small mammals, lizards, predators, and ticks. We found 22.8% of birds infected with B. burgdorferi s.l. and that the likelihood of avian B. burgdorferi s.l. infection was significantly associated with local host community composition and pathogen prevalence in California. Additionally, we found an average tick burden of 0.22 ticks per bird across all species. Predator and lizard abundances were significant predictors of avian tick infestation. These results indicate that birds are relevant hosts in the local B. burgdorferi s.l. transmission cycle in the western United States and quantifying their role in the spread and maintenance of Lyme disease requires further research.
The Tariff Structure in the Tagus-Segura Water Transfer
Authors: García-López Marcos , Montano Borja , Melgarejo Joaquín
Published: January 2022

The Tagus-Segura water transfer has generated significant value in the region that receives its water resources. Despite this value, some agents seek the cancellation of this important infrastructure, arguing economic, environmental, social, and political problems. With the aim of providing information on the efficiency of the Tagus-Segura aqueduct as a water resource management measure, especially in terms of the importance of water and the tariffs paid by the users of the aqueduct, this paper presents valuable information to analyse how to improve the functioning of the infrastructure. Thus, the southeast of Spain obtains a high return on the water received from the water transfer while covering all the financial costs derived from it. However, in 2017 a modification was introduced in the tariff that forced water users to cover the construction and fixed costs of the infrastructure as if the total amount of water agreed upon had been received, when in reality a lower amount had been received. This problem was not solved by the proposed tariffs for 2021, and it is therefore essential for the efficient operation of water transfer to modify these tariffs so that they are fair and reduce existing problems, thus avoiding the cancellation of an infrastructure that has not yet been amortised and which provides many benefits to the receiving region.
Differential Molecular Responses of Zebrafish Larvae to Fluoxetine and Norfluoxetine
Authors: Rodrigues Pedro , Cunha Virgínia , Ferreira Marta , Reis-Henriques Maria Armanda , Oliva-Teles Luís , Guimarães Laura , Carvalho António Paulo
Published: January 2022

The occurrence of psychopharmaceuticals in aquatic ecosystems is a growing problem. Fluoxetine (FL) and its metabolite norfluoxetine (NF) are selective serotonin reuptake inhibitors. Although they may be potentially harmful to non-target species, available knowledge on the effects of NF is sparse, relative to FL. This study aimed at contributing to the body of knowledge about the modes-of-action (MoA) of these compounds and their underlying mechanisms eliciting hazardous effects during the early development of the teleost model zebrafish (Danio rerio). One hour post-fertilisation (hpf), embryos were exposed up to 80 hpf to these compounds at levels found in surface waters and higher (FL, 0.0015 and 0.05 µM; NF, 0.00006 and 0.0014 µM). Developmental anomalies were observed at 8, 32 and 80 hpf. Larvae were collected at 80 hpf to assess the expression of 34 genes related to FL and NF MoA and metabolism, using qPCR (quantitative reverse transcription PCR). Results showed that both compounds elicited an increased frequency of embryos exhibiting abnormal pigmentation, relative to controls. Gene expression alterations were more pronounced in FL- than in NF-exposed larvae. Cluster Analysis revealed two groups of genes discriminating between the drugs. for their marked opposing responses. Globally, downregulation of gene expression was typical of FL, whilst upregulation or no alteration was found for NF. These clusters identified were linked to the adrenergic pathway and to the retinoid and peroxisome proliferator-activated nuclear receptors. Overall, our data contradict the prevailing notion that NF is more toxic than FL and unveiled the expression levels of genes drd2b, 5-ht2c and abcc2 as possible markers of exposure to FL.
Comparative Analysis of Developed Rainfall Intensity–Duration–Frequency Curves for Erbil with Other Iraqi Urban Areas
Authors: Kareem Dalshad Ahmed , M Amen Aumed Rahman , Mustafa Andam , Yüce Mehmet Ishak , Szydłowski Michał
Published: January 2022

Rainfall Intensity–Duration–Frequency (IDF) relationships are widely used in water infrastructure design and construction. IDF curves represent the relationship between rainfall intensity, duration, and frequency, and are obtained by analyzing observed data. These relationships are critical for the safe design of flood protection structures, storm sewers, culverts, bridges, etc. In this study, the IDF curves and empirical IDF formulas for the city of Erbil were developed for the first time by employing the annual maximum rainfall data for a period of 39 years (1980–2018), which is the only available recorded data. Statistical techniques such as Gumbel and Log-Pearson Type III (LPT III) were utilized to determine the IDF curves and empirical equations from daily rainfall data for several standard durations and return periods. The correlation between the rainfall intensities obtained from IDF curves and the empirical formula presented a reliable match, with a coefficient of determination of (R2 = 1). The results were compared to previously developed IDF curves and empirical formulas in Iraqi cities to show their reliability. Moreover, the results can be an initial step for authorities to establish required guidelines in the studied area, and in the design process of the storm water infrastructure of urban basins in the future.
Modeling Large Wood Transport in Semi-Congested Regime with Multiple Entry Points
Authors: Persi Elisabetta , Meninno Sabrina , Petaccia Gabriella , Sibilla Stefano , Armanini Aronne
Published: January 2022

Wood transport during flood events can increase inundation risk and should be included in numerical models to estimate the associated residual risk. This paper presents the application of a fully Eulerian model that considers floating wood as a passive superficial pollutant through the adaptation of the advection–diffusion equation. A set of experiments is performed in a sinusoidal flume with a contraction to model semi-congested wood transport. The variation of the log release position replicates the possible variability of large wood entrainment during real events. The experiments are used to validate the numerical model, providing a comparison of the wood mass transport. Different release modes are also tested. The model predicts the position of the released logs and the overall transported mass, independently of the release position and modes, with an accuracy that varies along the flume length and across the flume axis. The analysis of the experimental and numerical transport velocity shows that modulation of the transport velocity is needed to ensure adequate model performances for semi-congested conditions.
Spatiotemporal Heterogeneity of Agricultural Land Eco-Efficiency: A Case Study of 128 Cities in the Yangtze River Basin
Authors: Hu Yihang , Liu Xuan , Zhang Zhengyu , Wang Shengpeng , Zhou Haoyu
Published: January 2022

Analysis of spatiotemporal heterogeneity and evolutionary characteristics of agricultural land eco-efficiency is of great significance for achieving a rational use of natural resources and coordinated development of the agricultural economy as well as the ecological environment. In this study, we construct the “ecological space–agricultural production–carbon emission” framework, incorporate carbon emission intensity as an undesired output into the evaluation index system of agricultural land eco-efficiency, calculate the eco-efficiency of agricultural land in 128 cities in the Yangtze River basin from 2009 to 2018 by adopting the super-efficiency SBM model, and discuss the spatial and temporal changes using methodology such as hotspot analysis and kernel density estimation by ArcGIS. The results show the following. The overall trend of agricultural land eco-efficiency in the Yangtze River basin is increasing year by year and still has potential for improvement. However, there are significant discrepancies among cities, with the eco-efficiency of the downstream being much higher than that of the midstream and upstream regions, and demonstrating the pattern of “big dispersion–small agglomeration”. Some cities are still facing pressure to improve the eco-efficiency of agricultural land. Correspondingly, this paper puts forward optimization recommendations: Firstly, the downstream cities should give full play to their geographical advantages, actively introduce advanced production technologies, and reasonably allocate agricultural resources. Secondly, the upstream and midstream regions should formulate reasonable regional strategies in accordance with their natural resource endowments to improve the ecological benefits of agricultural land and narrow the regional disparities. This paper gives targeted policy recommendations at the levels of paying attention to education of farmers, providing incentives for ecological planting, strengthening agricultural infrastructure construction, reasonably controlling the use of agricultural materials, and increasing investment in agricultural pollutant emission management.
Flow Measurements Derived from Camera Footage Using an Open-Source Ecosystem
Authors: Meier Robert , Tscheikner-Gratl Franz , Steffelbauer David B. , Makropoulos Christos
Published: January 2022

Sensors used for wastewater flow measurements need to be robust and are, consequently, expensive pieces of hardware that must be maintained regularly to function correctly in the hazardous environment of sewers. Remote sensing can remedy these issues, as the lack of direct contact between sensor and sewage reduces the hardware demands and need for maintenance. This paper utilizes off-the-shelf cameras and machine learning algorithms to estimate the discharge in open sewer channels. We use convolutional neural networks to extract the water level and surface velocity from camera images directly, without the need for artificial markers in the sewage stream. Under optimal conditions, our method estimates the water level with an accuracy of ±2.48% and the surface velocity with an accuracy of ±2.08% in a laboratory setting—a performance comparable to other state-of-the-art solutions (e.g., in situ measurements).
Improving Transboundary Drought and Scarcity Management in the Iberian Peninsula through the Definition of Common Indicators: The Case of the Minho-Lima River Basin District
Authors: Maia Rodrigo , Costa Miguel , Mendes Juliana
Published: January 2022

Drought is one of the most damaging natural hazards in the Iberian Peninsula, causing varied socioeconomic and environmental impacts. To prevent these impacts, there must be close cooperation between Portugal and Spain, as the two countries share five river basins. However, regarding drought planning and management the two countries are clearly in different stages. Portugal approved a national drought plan in 2017, while Spain has already had drought plans in place for all River Basin Districts since 2007 and approved an updated version of these plans in 2018. The Spanish drought plans currently in place foresee two sets of indicators: prolonged drought and scarcity indicators. This paper presents the definition of similar indicators for the Portuguese part of the shared Minho and Lima river basins, according to European guidelines and in common with Spain, with the aim of developing a joint international drought management plan for these basins. For the period from October 1980 to September 2017, the comparison of the indicators obtained for the Portuguese parts of the basins with the corresponding Spanish ones shows a similarity in the occurrence of drought and scarcity in both parts of the basins, although with a higher prevalence of scarcity situations in the Lima Spanish part. This work was developed in close collaboration with the River Basin District competent authorities of both countries, aiming to be a prototype for the definition of new and comparable drought and operational scarcity indicators. Therefore, this work is a starting point for the creation of common tools for integrated drought management of transboundary basins in the IP.
Minimizing Errors in the Prediction of Water Levels Using Kriging Technique in Residuals of the Groundwater Model
Authors: Asadi Alireza , Adhikari Kushal
Published: January 2022

Groundwater monitoring and water level predictions have been a challenging issue due to the complexity of groundwater movement. Simplified numerical simulation models have been used to represent the groundwater system; these models however only provide the conservative approximation of the system and may not always capture the local variations. Several other efforts such as coupling groundwater models with hydrological models and using geostatistical methods are being practiced to accurately predict the groundwater levels. In this study, we present a novel application of a geostatistical tool on residuals of the groundwater model. The kriging method was applied on the residuals of the numerical model (MODFLOW) generated by the TWDB (Texas Water Development Board) for the Edwards–Trinity (Plateau) aquifer. The study was done for the years 1995 through 2000 where 90% of the observation data was used for model simulation followed by cross-validation with the remaining 10% of the observations. The kriging method reduced the average absolute error of approximately 31 m (for MODFLOW simulation) to less than 5 m. Furthermore, the residuals’ average standard error was reduced from 9.7 to 4.7. This implies that the mean value of residuals over the entire period can be a good estimation for each year separately. The use of the kriging technique thus can provide improved monitoring of groundwater levels resulting in more accurate potentiometric surface maps.
Long-Lasting Boiling-Wells: Geochemical Windows into the Tectonic Activity of the Maodong Fault (China)
Authors: Liu Lin , Jiang Yuehua , Zhou Xun , Li Yun , Zhou Quanping , Su Jingwen , Jia Junyuan , Yang Guoqiang , Jin Yang
Published: January 2022

The Maodong Fault (China) was mainly active during the Late Pleistocene. However, in the past century, numerous destructive earthquakes have occurred along the fault zone, indicating its continuing activity. Therefore, refined monitoring of the tectonic activity along the fault is required. Boiling-Wells located in the Maodong Fault Zone were selected for this purpose. The parameters, including the rare earth elements (REE) and gas components, such as CO2, Rn, and Total Volatile Organic Compounds (TVOC), in the wells were analyzed. By combining field observations with the analytical data, we constrained the relationships between the anomalies of the hydrochemical composition and the gas composition in the Boiling-Wells and the Maodong Fault: (1) CO2 and TVOC in the Boiling-Wells originated from Cenozoic magmatism and associated intrusive rocks. High concentrations of Rn are closely linked to tectonic activities of the Maodong Fault. CO2, TVOC, and Rn are all transported to the Boiling-Wells along the Maodong Fault, with CO2 acting as a carrier gas for Rn. (2) REE in the Boiling-Wells was mainly sourced from CO2 fluids that originated from deep-seated Cenozoic magmas and intrusive rocks. The concentrations of the REE and their distribution patterns were controlled by the input of CO2 fluids and by epigenetic processes. (3) The abnormally high contents of Ca2+, HCO3−, Pb2+, and Al3+ in the Boiling-Wells are attributed to the migration of externally-derived (deep) CO2 fluids through the Maodong Fault. (4) The anomalies of the gaseous (Rn, CO2, and TVOC) and hydrochemical components (Ca2+, HCO3−, Pb2+, Al3+, ∑REE, and REE patterns) in the Boiling-Wells are closely related to the tectonic activity of the Maodong Fault. Therefore, the long-lasting Boiling-Wells provide an excellent geochemical window into the evolution of the Maodong Fault. Our study documents that the contents and variations of specific hydrochemical and gaseous components of Boiling-Wells are well-suited geochemical tracers to identify and characterize the tectonic activity of the Maodong Fault. This method is also applicable for the monitoring of tectonic activities of major faults zones with comparable preconditions worldwide.
Willingness to Pay for the Maintenance of Green Infrastructure in Six Chinese Pilot Sponge Cities
Authors: Qiao Xiu-Juan , Randrup Thomas B.
Published: January 2022

Due to the increasingly devastating impact of pluvial flooding on human beings’ lives and properties in cities, the use of green infrastructure to manage stormwater onsite is becoming more popular worldwide. The maintenance of green infrastructure to ensure its function has become one of the most pressing tasks facing policy makers. However, there is limited research regarding the willingness to pay the stormwater fee as a form of maintenance funding. This study utilized contingent valuation data obtained from a survey of 1101 respondents living in six pilot sponge cities in China to estimate the willingness to pay for the green infrastructure maintenance. The findings indicated that two-thirds of all respondents were willing to pay, 17% would like to pay around 6–10 RMB/month (0.95–1.59 US dollars/month), and 17.8% would like to pay more than 20 RMB/month (3.2 US dollars/month). The educational level and age of the respondents were significant determinants of the probability of willingness to pay and the amount they would like to pay. Knowledge of the concept of sponge cities was another significant influencing factor for the willingness to pay, but it did not influence the amount of payment. The findings could help policy makers make better strategies regarding the maintenance of green infrastructure and its costs.
ANALYSIS OF COAL EXPORT DEVELOPMENT IN ACEH PROVINCE THROUGH RCA AND MCI APPROACH
Authors: Khairina Khalish , Syahputra Angga
Published: January 2022

This study aims to analyze  the development of coal’s export in Aceh Province by using Revealed Comparative Advantage (RCA) and Market Concentration Index (MCI). This study is descriptive quantitave research by using time series data for 6 years (2015 -2020), used data is value export of Aceh. RCA is used to analyze the competitive of coal, whereas, MCI is used  to analyze the ployment of coal’s export. RCA Index, since 2015 – 2019, is under 1 that means coal in Aceh has low competitiveness. RCA index in 2020, shows at 1,06 which means coal in Aceh has high competitiveness. MCI Index for Aceh’s coal always shows close to 1, which mean that coal’s export only concentrated to one country and coal’s export in Aceh is unscattered.
FINANCIAL PERFORMANCE ANALYSIS OF CONSUMER GOODS INDUSTRY COMPANIES LISTED ON THE JAKARTA ISLAMIC INDEX (JII) BEFORE AND DURING COVID-19
Authors: Hayati Husna , Rofizar Heny , Savitri Asmah , Syahputra Angga
Published: January 2022

Corona Virus Disease (Covid-19) that hit Indonesia has had a negative impact on many sectors. The
biggest impact is on the decline in economic capacity felt by various business sectors. The economic
downturn will also affect the company's financial performance. More specifically, the impact on the
company's financial performance is on the company's profitability ratios. This study aims to examine the impact of the Covid-19 pandemic on the financial performance of companies listed on the Jakarta Islamic Index (JII). The research population is 30 companies registered with JII. The sampling technique used is purposive sampling by setting criteria and selecting four companies that meet the criteria set by the author. The overall sample used is the Consumer Goods Industry sector which has remained in JII for 3 consecutive years. Data analysis in this study used the Wilcoxon Signed Rank Test. The results showed that there was a significant difference in Return on Assets before the Covid- 19 pandemic compared to during Covid-19. On the other hand, there is no significant difference in Return on Investment before Covid-19 compared to during Covid-19.
THE EFFECT OF POST TSUNAMI HOTEL TAX RECEIVING AND PARKING TAX ON ORIGINAL LOCAL REVENUE (PAD) PANDEGLANG REGENCY PERIOD 2015-2019
Authors: Pratiwi Refi , Wahyudi Tri
Published: January 2022

The Pandeglang Regency Local Tax Service (BP2D), which is in accordance with its authority as the coordinator of hotel tax collection and parking tax, is one of the Local Revenues. One indicator that reflects the independence and success of a region is the receipt of Original Local Revenue (PAD). The purpose of this study was to determine the effect of hotel tax receipts on Original Local Revenue (PAD), to assess the impact of parking tax receipts on Original Local Revenue (PAD), and to determine the effect of hotel tax receipts and parking taxes simultaneously on Original Local Revenue (PAD). ) at Pandeglang Regency 2015-2019. This research was designed using a quantitative research approach. The data collection technique used was secondary data. The research was conducted at The Pandeglang Regency Local Tax Service Agency (BP2D). The sample of this research is the 2015-2019 Pandeglang Regency budget report. The results of this study are hypothesis 1 there is no effect of hotel tax receipts on Original Local Revenue (PAD), hypothesis 2 there is no effect of parking tax receipts on Original Local Revenue (PAD), and hypothesis 3 does not influence hotel tax receipts and parking taxes simultaneously on Original Local Revenue (PAD) at Pandeglang Regency 2015-2019.
ANALYSIS OF INNOVATION STRATEGIES TO INCREASE THE COMPETITIVE ADVANTAGES OF ULOS PRODUCTS IN PEMATANGSIANTAR CITY
Authors: Halim Fitria , Sherly Sherly , Grace Ernest , Lie Darwin , Sudirman Acai
Published: January 2022

One of the production sectors that has become the flagship product of Pematangsiantar City is ulos cloth. Ulos cloth is a typical woven fabric of the Batak community developed for generations in North Sumatra, one of which is the city of Pematangsiantar. This study aims to explore various information related to the number of ulos craftsmen in Pematangsiantar city to facilitate the government in grouping these ulos craftsmen and as a first step to formulate an innovation strategy for the development of creative ulos fabric production to be able to develop superior products armed with knowledge. knowledge, creativity, innovation and being able to create jobs for the community. This type of research is qualitative with a one-shot model, namely an approach model by conducting one-time data collection on an object of research. The research subjects taken in this study were ulos craftsmen spread across eight sub-districts of Pematangsiantar City. The analysis was carried out in eight sub-districts in Pematangsiantar City. Data collection techniques using observation, interviews and questionnaires, field notes and documentation.The results of the study concluded that the innovation strategy applied by the ulos fabric craftsmen was not optimal, this was due to the limited capacity and opportunity to innovate, the ulos craftsmen experienced problems in making product innovations related to technological limitations caused by limited investment capital to buy new machines or equipment. to improve production processes and limited human resources who can operate new machines or make innovations that take advantage of technological developments.
IMPACT OF MEMBER'S DEPOSITS AND MEMBER'S LOANS ON THE REST OF BUSINESS PROFITS ON COOPERATIVE PARTNER MANDIRI, LIRIK DISTRICTS, INDRAGIRI HULU
Authors: Suharmiyati Suharmiyati , Iskandar Yenny
Published: January 2022

The purpose of this study was to gain an understanding of the savings and loan cooperatives as a whole. Apparently savings and loan cooperatives are an important part of the Indonesian economy and can be beneficial for the lives of members. So, this study aims to determine the implementation of savings and loan cooperative procedures from all parties, problems and benefits. Therefore, the main research method is interview. This study shows that the use of savings and loan cooperatives can provide solutions for speed, accuracy and accuracy in carrying out saving and loan data processing in order to get optimal results. So this cooperative was established for member savings, member loans and there will be a distribution of SHU for all members.The Mitra Mandiri Cooperative, Lirik Districts, which is located in the Lirik sub-district, was established in 2012, but since 2012 it has developed until now. The loan process is based on a joint responsibility system and most loans are used for education and additional business capital. Cooperative Mitra Mandiri Lirik Districts strives to empower its members and employees more strongly with regular education and training. Furthermore, there is recreation every year to encourage member approaches and emphasize a family atmosphere.One of the important parts of the Cooperative Mitra Mandiri Lirik Districts is Savings and Loans which has been rolled out until now running smoothly.
THE INFLUENCE OF PRICE AND PRODUCT QUALITY ON PURCHASE DECISIONS FOR DAIRY PRODUCTS KRUCIL KRUCIL ARGOPURO PROBOLINGGO
Authors: Tyas Yayuk Indah Wahyuning , Yatiningrum Agung
Published: January 2022

This research was conducted at the Krucil KUD Milk House with the research objectives to be achieved: (1) to determine simultaneously the significant effect of price and product quality on purchasing decisions at Krucil Argopuro Probolinggo KUD Milk House. (2) to find out partially the significant effect of price and product quality on purchasing decisions at the Krucil Argopro Probolinggo KUD Milk House. (3) to find out between the price and product quality variables that have a dominant influence on purchasing decisions at the Krucil Argopuro Probolinggo KUD Milk House. The population in this study were all consumers during the last 1 year as many as 7,241 people with samples taken using the Slovin formula as many as 100 people. By using a sampling technique that is random sampling. The type of research used in this research is quantitative research. The variables used include price, product quality, and purchasing decisions. The data analysis method from the research results is the quantitative description method using SPSS in the form of validity and reliability tests, classical assumption tests, multiple regression analysis, coefficient of determination, hypothesis testing. The results of the study are shown by multiple regression equations proving that price and product quality have a significant effect on purchasing decisions. And the results of partial hypothesis testing prove that price and product quality have a significant effect on purchasing decisions. The results of the dominant hypothesis test show that the X2 variable has a higher tcount value than the other independent variables.
COVID – 19 AT UNIVERSITY: SEEING THE INFLUENCE TRANSACTIONAL LEADERSHIP AND LEADERSHIP TRANSFORMATIONAL ON LECTURER PERFORMANCE THROUGH JOB SATISFACTION
Authors: Almaududi Said , Albetris Albetris
Published: January 2022

Job satisfaction and lecturer performance are increasing because of the role of transactional and transformational leadership. The purpose of this study is to examine and analyze the influence of these two leadership styles at Batanghari University with the main focus of study on Human Resource Management. This study uses a survey design in the form of verification research. The sampling design used in this study was stratified random. From all lecturers at Batanghari University, 100 respondents were taken as samples from the Faculty of Economics. Data obtained from questionnaires were collected and analyzed using PLS
INFLATION AND INTEREST RATE WITH EXCHANGE AS INTERVENING VARIABLES : ON STOCK RETURN
Authors: Novriyani Novriyani
Published: January 2022

This research aims to find out Interest Rates and Inflation With Exchange Rates As Intervening Variables: Stock Returns. This type of research uses secondary data. The population of manufacturing companies listed on the Indonesia Stock Exchange (IDX) in 2014-2020. Sampling techniques used purposive sampling. The research population is a company registered with PT. IDX and sample of 8 companies. The data analysis method used is Path Analysis with SPSS. The results explained that inflation has a positive and insignificant effect on stock returns. Interest rates have a positive and insignificant effect on stock returns. Inflation has a positive and significant effect on the exchange rate. Interest rates have a positive and significant effect on the exchange rate. Inflation and return of stocks through exchange rates have a positive and significant effect on the exchange rate. Interest rates and stock returns through exchange rates have a negative and significant effect on the exchange rate. exchange rates have a positive and significant effect on stock returns.

Keywords : Inflation, Interest Rate, Stock Return and Exchange Rate
THE POTENTIAL AND EFFECTIVENESS OF REGIONAL RETRIBUTIONS INDRAGIRI HULU DISTRICT
Authors: Heriasman Heriasman , Suwaji Suwaji , Warnadi Warnadi
Published: January 2022

This study aims to determine the potential and effectiveness of regional revenue receipts from regional levies in Indragiri Hulu Regency. This study uses a descriptive approach designed to obtain answers to the research objectives. This research data comes from the collection of documents, interviews and data on regional retribution receipts for 2014 – 2020 from the Transportation Agency of Indragiri Hulu Regency. Data analysis is explained by using Potential Analysis, Contribution, Growth Rate and Potential Matrix, and effectiveness ratio. The results of the study show that the potential for regional levies, on average, has the potential to be developed, but in terms of management and implementation effectiveness, it is still not optimal. Based on quantitative data analysis, parking fees are categorized as potential with positive growth, motor vehicle testing fees have good growth opportunities and have the potential to be developed, while terminal fees and route permit fees are underdeveloped categories. Based on the effectiveness ratio analysis, parking fees are categorized as very effective, motor vehicle testing fees are included in the fairly effective criteria, terminal fees are quite effective, and route permit fees are categorized as quite effective.
INFLUENCE COMPANY SIZE, CAPITAL STRUCTURE, DIVIDEND POLICY ON FINANCIAL PERFORMANCE WITH BIODIESEL PRODUCTION AS MODERATING VARIABLES IN PALM OIL PROCESSING COMPANIES ON THE INDONESIA STOCK EXCHANGE (IDX)
Authors: Winarsih Winarsih , Efni Yulia , Rokhmawati Andewi
Published: January 2022

This study aims to determine and analyze firm size, capital structure, dividend policy on the company's financial performance. To analyze biodiesel production strengthen the relationship between firm size, capital structure, dividend policy and company financial performance. The population in this study is the use of company data included in the palm oil processing sector companies that went public on the Indonesia Stock Exchange (IDX) in the period 2014 to 2019. The sample in this study was 12 companies that met the sampling characteristics that have been determined. The analytical technique used in this research is PLS Structural Equation Modeling (SEM) which is operated through the WarpPLS.5.0 program. The results of the study show that the size of the company and capital structure on financial performance. Dividend policy has no effect on financial performance. Company size, capital structure have a significant effect on financial performance with Biodiesel Production as a Moderating Variable. The results of financial research on dividend policy have no effect on company performance with biodiesel production as a moderating variable
ANALYSIS OF FINANCIAL PERFORMANCE AT THE KP-RI KOPEKA SAVING AND LOAN COOPERATION (KSP) KOPEKA INDRAGIRI HULU REGENCY
Authors: Yaspita Hasanah , Gustika Gita Sari
Published: January 2022

In essence, the financial performance of a cooperative can be measured and viewed through financial statements by analyzing financial statements. The financial report is a financial list that is directly related to the financial position and financial operations, both of which provide information regarding the financial condition of the cooperative. In the measurement of financial position, the elements that are directly related are assets, liabilities and equity. One of the analytical techniques is ratio analysis which can provide clues that describe the condition of KSP KP-RI Koppeda, Indragiri Hulu Regency, especially in the financial sector.This study aims to test and analyze financial performance using financial ratio analysis methods: (1) Liquidity Ratio which is calculated based on Current Ratio and Quick Ratio, (2) Solvency ratio calculated based on Debt to Equity Ratio and Debt to Total Assets Ratio, (3) Profitability Ratio calculated based on the Net Rate of Return On Investment and Return On Equity. The object used in this study is financial performance in the form of a Balance Sheet and Profit and Loss Statement of KSP KP-RI Kopeka, Indragiri Hulu Regency for the period 2016 to 2020. The data used is secondary data. The data analysis method used was quantitative descriptive analysis technique, which is an analysis that describes by calculating the ratios in the financial statements using certain formulas.The results showed that the financial performance of the Savings and Loans Cooperative (KSP) KP-RI Kopeka, Indragiri Hulu Regency was in poor condition, both from the ratio of liquidity, solvency and profitability. This situation is illustrated by the condition of current assets that have not been able to meet current liabilities. And their own capital and total assets have not been able to meet the total debt. And Cooperatives have not been able to generate the remaining operating results from their own capital and total assets used.
Coleções zoológicas didáticas: uma ferramenta para a conservação da biodiversidade costeira
Authors: João Marcio Camargo Araujo , Sá Helton Souza de , Souza Graziela Alexandre , Gadig Otto Bismarck Fazzano , Pinheiro Marcelo Antônio Amaro , Talamoni Ana Carolina Biscalquini
Published: February 2022

As Coleções Zoológicas Didáticas (CZD), quando contextualizadas, podem potencializar o ensino de zoologia e auxiliar os processos relativos à preservação e conservação das espécies. Este estudo relata uma experiência de Projeto de Ensino que, visando contribuir para ações de Educação Ambiental e o ensino e aprendizagem de zoologia, criou e implementou uma CZD em Escola Técnica do Município de São Vicente (SP). O material reuniu 30 espécies representativas da biodiversidade costeira do Litoral Centro de São Paulo, com potencial interdicisplinaridade a ser trabalhada nas aulas de ciências e biologia. Para implementar a CZD, foi oferecido um curso aos docentes da escola, além de material de apoio ao uso dessa coleção.
Evaluation of the relationship between preeclampsia and positive rectovaginal culture of group B Streptococcus and Helicobacter pylori positive serology
Authors: Saghafian Larijani Samaneh , Biglari Abhari Maryam , Mirfakhraee Hosna , Niksolat Maryam , Aminpanah Danesh
Published: January 2022

Introduction: Identifying the incidence of pathogen colonizations in pregnant women with preeclampsia can be effective in providing proper treatment and reducing complications. Objectives: We evaluated the frequency and association between positive rectovaginal culture of group B Streptococcus (GBS) and positive Helicobacter pylori serology with preeclampsia in two groups of pregnant women (with and without preeclampsia). Patients and Methods: The present case-control study included pregnant women with preeclampsia and healthy pregnant controls during 2019-2020. Blood and rectovaginal samples were obtained and the data were statistically analyzed using SPSS software. Results: Fifty-four people were included in the study. The mean gestational age was 36 ± 3.4 months in the preeclampsia group and 37 ± 2.9 months in the control group. There was no significant relationship between preeclampsia and H. pylori-positive serology (P=0.84). Additionally, the association between positive H. pylori serology and the severity of preeclampsia was not significant (P=0.15). However, there was a significant relationship between positive H. pylori tests with early- and late-onset preeclampsia (P=0.04). However, there was no statistically significant relationship between the positive rectovaginal culture of GBS and preeclampsia, the severity of preeclampsia, the onset time, or the weight of newborns. Conclusion: There was a significant relationship between H. pylori infection and late-onset preeclampsia in preeclamptic mothers. H. pylori screening and eradication therapy before pregnancy can prevent preeclampsia and its serious consequences in both the mother and the fetus.