bluuebunny/crossref_metadata_2025 huggingface dataset:
DYNAMICS OF THE ETIOLOGICAL STRUCTURE OF SALMONELLOSIS IN BULGARIA AND SENSITIVITY TO ANTI‐BACTERIAL AGENTS FOR THE PERIOD 2016 – 2019
Authors: Pavlova Maria , Kamenov Galin , Alexandrova Ekaterina , Velev Valeri , Kantardjiev Todor
Published: December 2022

Background. In recent years, some features of salmonellosis have been noted: an increase in morbidity all around the world, which is accompanied by an increase in the number of isolated serotypes from humans, animals and food; an increase in sporadic diseases and multi-countries Salmonella outbreaks.
Material and methods. For the period 2016 - 2019 in the National Reference Laboratory for Enteric Infections, Pathogenic Cocci and Diphtheria 2 696 Salmonella isolates from all over the country have been confirmed. All of the strains were epidemiologically and microbiologically examined, and  tested for antimicrobial resistance.
Results. Salmonellosis is caused by several dominant for Bulgaria serotypes - is for S.Enteritidis and S.Typhimurium take the leading place, followed by Salmonella 1,2,5,12: i: -, Infantis, Paratyphi B Java, Kottbus, Corvallis, Derby, Dublin.
Conclusions. Given the widespread transfer of Salmonella through the exchange of food and animals, and international tourism, the microbial landscape of salmonellosis is becoming more diverse, though the leadership of S. Enteritidis and S. Typhimurium has been maintained in the recent years, both worldwide and Bulgaria.
Mortality rate and prognostic factors for poor outcome in HIV-infected Bulgarian patients with Pneumocystis pneumonia over a 3-year period
Authors: Yancheva Nina , Strashimirov Dimitar , Nikolova Maria , Alexiev Ivailo , Ivanova Aleksandra , Tsvetkova Nina
Published: December 2022

Background: In spite of the use of combination antiretroviral therapy and specific prophylaxis, Pneumocystis pneumonia remains one of the most common AIDS-defining disease with high mortality rate.
The aim of this study is to analyze the cases of pneumocystis pneumonia over a three-year period by means of assessing the mortality rate and the prognostic factors for the outcome of the disease.  
Material and methods: Epidemiological, clinical, laboratory and demographic data were analyzed for 13 HIV-infected patients with proved pneumocystis pneumonia, hospitalized at the AIDS Department over the period January 2017–December 2019. For data processing we used different methods of descriptive statistics.
Results: All presented patients have extremely severe immune deficiency and other opportunistic infections or AIDS-related diseases. The diagnosis of pneumocystis pneumonia was confirmed with PCR in 76.9% of the patients and with Giemsa staining for cysts and trophozoites in 23,1% of the patients. Most of our patients are male (84,6%) and the leading mechanism of HIV infection is unprotected homosexual contact. The mean age of the patients presented is 37.4 ± 10.27. Our results showed high PJP mortality (46.3 %), despite the applied etiological therapy.
Conclusions: Pneumocystis jirovecii pneumonia (PJP) continues to be a life-threatening infection in HIV-infected patients with severe immune suppression. PJP mortality continues to be high, and there is a statistically significant dependence on age, male sex, low CD 4 T+ cell count, high viral load of HIV, low blood albumin, and the number and severity of comorbidities.
PREVALENCE OF MEASLES IGG ANTIBODIES AMONG HEALTHCARE WORKERS IN BULGARIA
Authors: Krumova Stefka , Andonova Ivona , Stoitsova Savina , Stefanova Radostina , Vladimirova Nadejda , Parmakova Kremena , Kurchatova Anna
Published: December 2022

Background: Healthcare workers are at greater risk of acquiring measles than the general population. Transmission occurs from infected patients to staff and from infected staff to patients and colleagues. In inpatient and outpatient settings, susceptible patients suffering from other conditions, especially the elderly and severely ill patients in intensive care units are at a high risk of severe disease or death if infected with measles. The most effective preventive measure against measles is vaccination with two doses of a measles-containing vaccine.
Aim: To perform a serological assessment of the presence of measles IgG antibodies among healthcare workers.
Materials and Methods: The present study involves serological testing performed on samples from persons working in hospitals and Regional Health Inspectorates in the country. Screening started in connection with a reported measles outbreak in Bulgaria in 2019, and continued into early 2020. An indirect ELISA assay for the detection of specific measles IgG antibodies in serum samples was used.
Results: The tested 152 healthcare workers were from 5 regions of the country, i.e. Sofia-capital (n=87), Burgas (n=6), Blagoevgrad (n=5), Dobrich (n=8) and Pazardzhik (n=46). Anti-measles IgG antibodies were detected in 85.5% of the participants (130/152). Negative results, indicating a possible lack of protective immunity against measles, were obtained primarily in samples from persons younger than 40 years of age.
Conclusion: Screening to identify healthcare workers who lack presumptive evidence of protective immunity against measles should be reinforced, especially among younger healthcare workers, in order to minimize the risk of measles both among healthcare workers and among patients.
The Strict and Broad Views of Intention Again
Authors: Lee Patrick ,   The National Catholic Bioethics Center
Published: December 2022

I reply to Steven Jensen’s article, “Phoenix Rising from the Ashes: Recent Attempts to Revive New Natural Law Action Theory,” which appeared in this journal in 2020. His arguments helpfully clarify where the disagreements between the strict and broad views of intention lie but, I argue, fail to refute the arguments and explanations he criticizes. I argue he misinterprets the strict view’s reference to necessity in its criterion for what is intended. I also argue against what he labels as the “identity thesis,” and against his attempt to show that the strict view (or New Natural Law theory of action) leads to the absurdity that most acts of adultery are not actually adultery.
The Contralife Argument Revisted
Authors: Masek Lawrence ,   The National Catholic Bioethics Center
Published: December 2022

In a recent issue of this journal, Steven Dezort criticizes two versions of the contralife argument, including my version and a version defended by some prominent new natural law theorists. In this essay, I argue that people should accept the contralife argument even if they disagree with other principles of new natural law theory. To defend this thesis, I correct some misstatements about the contralife argument and identify basic disagreements about defining actions and respecting human life.
Students’ Ways of Understanding Academic Writing
Authors: Sulaiman Suciyati
Published: December 2022

Universities have placed academic writing skills as valuable skills for university students; some universities have compulsory modules for undergraduates, and some have dedicated writing centers for students to seek assistance in composing academic writing. Without a doubt, writing in English, particularly for those whose first language is not English, is considered a complex and challenging skill to master. In addition, academic writing is even more complex, as an essential element of academic writing is the inclusion of claims and opinions. Therefore, the struggle observed is that students cannot voice their opinions in a formal writing context, which perhaps resulted in the structure of the written piece not being coherent and cohesive as per the standard of academic writing. In order to achieve its aim, this study will use a phenomenographic research approach to investigate the undergraduate’s conceptions of academic writing. A phenomenography approach is used in this study because students’ experience composing academic writing would be the focus, and the research object would look at the variation in ways of experiencing such phenomena. The study relates to learners from various faculties at the University with a common ground of their English language proficiency that is used to gain entry to the University.
INTENSITAS SANTRI MENGIKUTI PENGAJIAN KITAB SULAMUTTAUFIQ BAB SHALAT HUBUNGANNYA DENGAN PELAKSANAAN SHALAT BERJAMAAH
Authors: Basit Abdul , Muhyani Muhyani , Yono Yono
Published: December 2022

Tujuan Penelitian ini adalah: (a) Untuk mengetahui pemahman santri terhadap Kitab Sulamun Taufiq Bab Shalat. (b) Untuk Mengetahui akan kesadaran akan utamanya shalat berjamaâ€™ah. (c) Untuk mengetahui Hubungan pemahaman Kitab Sulamun Taufiq Bab Shalat dengan kesadaran santri shalat berjamaah. Hasil penelitian ini: (a) Intensitas santri mengikuti pengajian Kitab Sulamuttaufiq Bab Shalat adalah cukup. Hal ini dapat dibuktikan dengan dengan hasil yang diperoleh adalah mencapai nilai rata-rata sebesar 3,19 yang termasuk pada kategori cukup karena nilai tersebut berada pada interval 2,5 â€“ 3,5. (b) Pelaksanaan shalat berjamaah santri adalah tinggi. Hal ini dapat dibuktikan melalui data kuantitatif hasil dari angket yang di sebarkan kepada 40 responden. Hasil yang diperoleh adalah mencapai nilai rata-rata sebesar 3,57 yang termasuk pada kategori tinggi karena nilai tersebut berada pada interval 3,5 â€“ 4,5. (c) Hubungan antara intensitas santri mengikuti pengajian Kitab Sulamuttaufiq Bab Shalat dengan pelaksanaan shalat berjamaah, terdapat hubungan yang signifikan, hal ini terbukti dari hasil perhitungan koefisien korelasi antara kedua variabel tersebut mencapai nilai sebesar 0.63 yang berarti termasuk ke dalam kategori sedang, karena nilai tersebut berada pada interval 0.41 â€“ 0,70. Dan dari uji coba hipotesis t hitung = 4,97 dan t tabel Â­= 1,69, dan karena t hitung > t tabel maka hipotesis alternatif diterima. Oleh karena itu pengaruh variabel X terhadap variabel Y sebesar 12% dan 88% lagi dipengaruhi oleh faktor lain.
MODEL BISNIS CANVAS PADA TEMAN BUNGA
Authors: Prayudi Dicki
Published: December 2022

Berbagai jenis usaha mikro dikembangkan oleh penggiat usaha barang dan jasa dewasa ini. Seiring dengan jumlah permintaan dan tersedianya kemudahan penjualan melalui flatform digital seperti market place, mendorong usahawan menjadi kreatif membuat jenis usaha baru yang lebih dicari produknya, salah satunya adalah Teman Bunga yang fokus menjual bunga kering impor yang berkualitas. Perilaku konsumen masih memandang harga tinggi dan pengiriman yang lama apabila memesan langsung di luar negeri menjadikan alasan Teman Bunga membuat store di Sukabumi. Penelitian ini bertujuan untuk membuat formula strategi bisnis yang dapat digunakan untuk perusahaan dengan menggunakan Bisnis Model Kanvas. Metode penelitian menggunakan analisa deskriptif kualitatif. Hasil penelitian mendapatkan sebuah strategi bisnis model kanvas dengan strong part terdapat di Customer Segment terkait dengan arah penjualan outlet dengan skema B2C dan B2B, sementara low part berada di Key Partner terutama yang berhubungan dengan kebijakan pemerintah terkait nilai kurs dan regulasi ekspor impor. Pengembangan selanjutnya diharapkan dapat meminimalisir aspek-aspek yang beresiko tinggi terhadap kelangsungan bisnis. Model bisnis kanvas di Teman Bunga manambahkan indikasi aspek kebijakan kurs, bea cukai serta aturan ekspedisi karena mengambil bahan utama dari luar negeri.
PENGEMBANGAN INSTRUMEN HASIL BELAJAR MATEMATIKA SISWA (TES PILIHAN GANDA)
Authors: Syahlani Achmad , Setyorini Desy
Published: December 2022

Tujuan dari penelitian ini adalah melakukan pengembangan instrumen tes untuk mengukur hasil belajar matematika siswa dalam materi pembelajaran himpunan. Penelitian dilakukan di SMP Negeri 267 Jakarta. Populasi penelitian adalah seluruh siswa kelas VII dengan sampel adalah salah satu kelas VII yang dipilih dengan teknik Cluster Random Sampling, yang terdiri dari 30 siswa. Penelitian ini menggunakan metode penelitian pengembangan atau Research and Development (R & D). Butir-butir soal instrumen disusun dengan menggunakan soal pilihan ganda dengan 4 alternatif pilihan jawaban. Data yang terjaring dari hasil uji coba instrumen pada sampel, diolah dan dianalisis dengan menggunakan program ITEMAN (Item and Test Analysis), yang terdiri dari uji validitas butir instrumen dan uji reliabilitas instrumen. Dari pengolahan dan analisis data hasil uji coba instrumen diperoleh hasil: (1) Instrumen final terdiri dari 19 butir soal yang valid dari 25 butir soal yang diujicobakan; (2) Butir-butir soal yang valid tetap mewakili kelima kompetensi dasar yang disusun sebelum uji coba; (3) Koefisien reliabilitas instrumen final sebesar 0,737.
RANCANG BANGUN SISTEM INFORMASI AKUNTANSI ARUS KAS PADA PERUSAHAAN DAGANG DAN JASA
Authors: Ferliyanti Herlina , Yudithia Dewi Firsty
Published: December 2022

Sistem informasi akuntansi arus kas meliputi transaksi arus masuk dan arus keluar kas yang terjadi didalam kegiatan operasional perusahaan. Arus kas masuk berasal dari pendapatan yang diterima perusahaan, aktivitas pembiayaan maupun aktivitas investasi. Sedangkan arus kas keluar dikeluarkan untuk membiayai operasional perusahaan maupun kewajiban baik jangka pendek maupun jangka panjang perusahaan. Sistem informasi arus kas merupakan sistem informasi yang digunakan untuk mempermudah aktivitas perusahaan dalam menghasilkan laporan arus kas yang dibutuhkan manajemen secara efektif dan efisien. Karena sistem informasi akuntansi arus kas digunakan sebagai penunjang bagi manajemen untuk memudahkan dalam pengambilan keputusan
EVALUASI KUALITAS PERANGKAT LUNAK PADA APLIKASI PCPMOBILE
Authors: Harun Muhammad
Published: December 2022

Adanya akan aplikasi untuk dapat mempermudah pekerjaan disaat WFH PT.PCP selama pandemi Covid-19 sangat diperlukan dukungan IT dengan di buatnya Aplikasi pcpmobile untuk mengakomodir pekerjaan harian dilakukan secara virtual untuk dapat menekan laju penyebaran virus. Analisa metode PIECES perlu dilakukan seiring dengan pengguna aplikasi yang terus melonjak dengan menguraikan ke dalam 6 fokus yaitu Performance, Information and Data, Economy, Control and Security, Eficiency dan Service serta melakukan pengukuran kualitas perangkat lunak berdasarkan Model ISO/IEC 25010:2011 yang merupakan bagian dari Systems and software Quality Requirements and Evaluation (SQuaRE) dengan mengkategorikan kualitas produk menjadi karakteristik yang terdiri dari Functional Suitability, Performance efficiency, Compatibility, Usability, Reliability, Security, Maintainability, Portability.
ANALISIS SISTEM PENGELOLAAN SAMPAH PERKOTAAN DI PERUMAHAN PRESAK TIMUR KOTA MATARAM
Authors: Wahyudin Wahyudin
Published: December 2022

Pengelolaan sampah dewasa ini menjadi perhatian khusus bagi seluruh stakeholders, karena masih adanya permasalahan yang ditimbulkan oleh sampah. Pada umumnya konsep pengelolaan sampah sudah bagus, namun implementasinya yang masih kurang baik mengakibatkan kinerja pengelolaan sampah tidak optimal. Hal demikian terjadi juga di lingkungan perumahan Presak Timur Kelurahan Pagesangan Timur Kota Mataram, dimana pengelolaan sampahnya tidak optimal. Tujuan penelitian ini adalah 1) untuk mengetahui timbulan dan komposisi sampah, 2) untuk mengetahui sistem pengelolaan sampah di lingkungan Presak Timur. Penelitian ini menggunakan pendekatan rasionalistik (deduktif). Proses penelitian dimulai dengan mengidentifikasi permasalahan pengelolaan sampah di lingkungan Perumahan Presak Timur Kota Mataram dengan cara observasi dan wawancara. Hasil penelitian ini menunjukkan bahwa aspek teknik operasional pengelolaan sampah di lingkungan perumahan Presak Timur masih dibawah standar pengelolaan sampah yang baik. Hasil analisis menunjukkan bahwa pengelolaan sampah masih perlu peningkatan pada setiap tahapan pengelolaan sampah, dan yang harus diutamakan untuk digalakkan adalah kegiatan pemanfaatan dan pengolahan sampah, yang mana hal ini belum dilakukan di perumahan Presak Timur
ANALISIS STUDI KELAYAKAN BISNIS PENGEMBANGAN PRODUK OLAHAN PANGAN BEKU SIOMAY PADA UMKM INDOMITRA CIPTA PANGAN
Authors: Isroni Isroni , Rudianto Rudianto
Published: December 2022

This study aims to analyze the feasibility of frozen food business for new products. The method used in this research is descriptive method. The object of the research is CV Indomitra Cipta Pangan. The results of the research and discussion, the feasibility of business development recommends that it is feasible to run. Non-financial analysis is seen from market and marketing aspects, legal and business legal aspects, operational activities aspects, management and business organization aspects, socio-economic aspects and environmental aspects. From the six aspects, the researcher concludes that non-financially business development is feasible. While the financial analysis shows the data, the initial cash flow payback period is 1 year 2 months 7 days. the NPV value at the 6% discount factor is Rp. 884,600,301, which means it has a positive value. this means that it is feasible to run because the NPV value is positive / NPV> 0. The IRR figure shows 35.8%. With the invested capital of Rp 220,365,000, when compared to the 6% interest rate for the average per year bank interest, the investment is acceptable because the IRR value is above interest or the cost of capital is 6%. The PI value is 5.01. declared eligible to be accepted and/or executed because PI > 1.0. Break Event Points will be earned in the second year with BEP unit 7126 and BEP IDR 213,777,750.
KOMUNIKASI POLITIK POLITISI PARTAI ( Studi Kasus Presentasi Diri Politisi DPP Partai Golkar Pada Pemilu 2019)
Authors: Abdullah Samri , Yuliasari Ika
Published: December 2022

This study aims to communicate political party politics. Self-presentation study of Golkar Party Politicians in the 2019 Election. The type of research used is qualitative. The method used in the case study. This research was conducted at the office of the Central Executive Board of the Golkar Party, West Jakarta. The results of this study were summarized into five points, as follows; First, elections are a political constellation filled with nuances of the image of politicians as well as political strategic steps at the executive level. As a political party that has been well consolidated, the Golkar Party is expected to have a capable capacity when it comes to having the image of the figures it has. So we need a leader who has a new breakthrough with a style and approach in leading that must be better than his predecessor.
Froude Number Effects on Two-Dimensional Hydrofoils
Authors: Hough G. R. , Moran J. P.
Published: December 2022

The performance of a two-dimensional hydrofoil of arbitrary camber, moving at arbitrary Froude number at a constant depth below a free surface, is considered. The treatment is based upon the use of singularity distributions and thin foil theory. By assuming an appropriate series form for the vortex distribution representing the hydrofoil, it is shown that the problem can be reduced to the solution of a set of linear algebraic equations. These are solved by a collocation procedure. Numerical results for the performance characteristics are then given for several hydrofoil configurations, submergence depths, and Froude numbers. These indicate that operation at Froude numbers greater than about ten is practically equivalent to operation at infinite Froude number. However, at lower values of the Froude number and for all the configurations considered, Froude number effects are important, even at submergence depths of several chord lengths.
Manual de publicação da Editora Udesc: instruções e procedimentos
Authors:   Universidade do Estado de Santa Catarina, Kroeff Marcia Silveira
Published: December 2022

O manual tem a finalidade de orientar os autores que pretendem publicar suas obras originais pela Editora UDESC. Foi criado a partir da revisão do Guia de publicação Editora UDESC, de 2104. Foram incorporados conceitos e atualizações com base nas normas da Associação Brasileira de Normas Técnicas, principalmente aquelas destinadas aos livros e folhetos, assim como nas normas de apresentação tabular da Fundação Instituto Brasileiro de Geografia e Estatística (IBGE). A primeira edição do “Manual de publicação da Editora UDESC: instruções e procedimentos”, foi elaborada em 2019. Em 2022, por decisão do Conselho Editorial da UDESC, o manual foi revisto, gerando então a 2ª edição.
Neoliberalism in the North American University
Authors: M. Pelly R. Duncan , Boje David
Published: December 2022

This paper uses observations from empirical articles and personal experiences of the authors to explore issues associated with the rise of neoliberalism and academic capitalism in the contemporary public university. It frames these issues as stemming from conflicting ontologies between academicians who adhere to the differentiated individual ontology and university administrators who favor the undifferentiated individual ontology. To overcome the disconnect, a differentiated relational ontology that adheres to principles of Mary Parker Follett and Alfred North Whitehead is proposed. The driving force behind this ontology can be highlighted through a communicated crisis, and a specific application of Follett’s differentiated relational ontology is Ensemble Learning Theory (ELT). A potential limitation of this study is generalizability, because the focus is centered on North American public universities and anecdotes are used to characterize a broader educational problem. This evolution is pertinent to academicians and administrators because the ontological impasse experienced in North American public universities threatens their existence as institutions, and has a broader and potentially negative impact on the quality of educational focus and output.
FUZZY-LOGIC-BASED ERGONOMIC ASSESSMENT IN AN AUTOMOTIVE INDUSTRY
Authors: Kamala Vijayakumar , Robert T Paul
Published: December 2022

The objective of this study was to develop and evaluate a tool for measuring an organisation’s ergonomic level. The study was carried out to fill a research gap in which no attempt had been made to design an index for evaluating a company’s ergonomics. An ergonomic index measuring model with 15 criteria using a fuzzy logic technique was developed during this study. The fuzzy ergonomic index (FEI), which represents the ergonomic level of the company, and the fuzzy performance importance index, which assists in resolving ergonomics barriers, were then calculated. The findings show that the model is capable of analysing ergonomics adequately and has practical application. Application of the methodology presented in this paper will reveal the measures necessary to improve an organisation’s ergonomic level. Keywords Fuzzy Ergonomic Index; Manufacturing; Fuzzy Logic; Ergonomic Assessment;
BASE MODELS FOR SIMULATING THE SOUTH AFRICAN FORESTRY SUPPLY CHAIN
Authors: Laubscher Jennimi , Bekker James , Ackerman Simon
Published: December 2022

The South African forestry supply chain is a complex system that involves both the production of trees (site preparation, re-establishment, tending, and maintenance operations) and the production and distribution of wood products from plantation stands to the pulp- and sawmills. This paper reports on a study that investigated the suitability of discrete-event simulation for modelling forestry supply chains. As part of a larger research project, two discrete-event simulation models with bi-objective optimisation of the South African pulpwood and saw-timber supply chains respectively were developed. The simulation models were developed for each supply chain by first mapping out the supply chain processes through subject-matter expert and stakeholder consultation. Thereafter simulation concept models were developed, and the required input data were identified, acquired, and verified. The simulation models were verified and validated to be realistic representations of the supply chains that they imitate. The study concluded that the simulation models demonstrated the ability to perform scenario analysis and bi-objective optimisation. It was also demonstrated that the two disciplines of industrial engineering and forestry science can successfully collaborate. Keywords supply chain; simulation; forestry; bi-objective optimisation
The Application of CSR and CSV Concepts in Company Marketing Activities
Authors:   Department of Marketing, Faculty of Management, University of Lodz, Poland, Grzegorczyk Wojciech
Published: December 2022

Purpose: The purpose of this publication is to attempt to determine the applicability of the basic assumptions of the CSR (Corporate Social Responsibility) and CSV (Creating Shared Value) concepts in the process of building marketing strategies, their types and the use of marketing-mix tools. Design/methodology/approach: In achieving the objective, a method of critical analysis of national and international literature relating to these issues (CSR and CSV concepts) was used. Findings: The concepts of CSR and CSV can be applied to the marketing strategies of companies. This applies in particular to the organization of marketing in the enterprise, its mission, the selection of markets, the establishment of the buyer segment and the marketing-mix tools. There should be an extension of the marketing cell within the enterprise, which is responsible for creating the marketing strategy and incorporating shared value into the marketing-mix policy. The selection of buyer segments from the point of view of social needs will make it possible to create the company’s offer in the form of shared economic-social value and to include companies from local markets in its creation and distribution channels. Changes to product policy are also needed, which should include the creation of shared-value products. Research limitations/implications: Difficulties in understanding the distinctiveness of the concepts of CSR and CSV by companies. Further research should focus on these problems and the actions taken by companies as a result of these concepts. Practical implications: These include proposals to broaden the scope of marketing research conducted by companies and to focus their product innovation policies on products that create shared value. Originality/value: The text presents issues rarely discussed in the marketing literature on the need for companies to take into account in their marketing strategies changes in the environment, related legislation, the needs of local communities, high levels of buyer education and increasing consumer requirements towards product suppliers.
Sinopsis de "Conocimiento expropiado"
Authors: Broncano Fernando
Published: December 2022

Summary of Conocimiento expropiado
Resumen: El libro Conocimiento expropiado trata varios de los temas nucleares de la epistemología política. Parte de la hipótesis de que en la interacción entre posiciones epistémicas y posiciones sociales se producen daños epistémicos que producen daños sociales. El marco teórico del libro es la epistemología de virtudes extendida a los aspectos sociales. Desde estos dos puntos de vista examino temas como la injusticia epistémica, las ignorancias estructurales, la opresión epistémica y las relaciones entre epistemología y orden social democrático.
Abstract: The book Conocimiento expropiado deals with several of core issues of political epistemology. It starts from the hypothesis that in the interaction between epistemic positions and social positions epistemic certain harms are produced that amount to social harms. The theoretical framework of the book is virtue epistemology extended to social aspects. From these two points of view, I examine issues such as epistemic injustice, structural ignorances, epistemic oppression and, finally, the relations between epistemology and democratic social order.
Palabras clave: Epistemología política, injusticia epistémica, epistemología y democracia.
Keywords: Political epistemology, epistemic injustice, epistemology and democracy.
Reivindicaciones del crédito epistémico en el contexto social
Authors: Navarro Jesús
Published: December 2022

Claims of epistemic credit in social context
Resumen: En este ensayo explico la propuesta fundamental de Conocimiento expropiado (Broncano 2020) en el marco agencial y fiabilista que asume el autor. A continuación, me centro en su análisis de las situaciones de injusticia testimonial, contraponiendo los caminos seguidos por Miranda Fricker (enfocado en el prejuicio del intercambio testimonial) y Broncano (enfocado en el desajuste estructural). Tras señalar las deficiencias de cada modelo, apunto una propuesta alternativa: la injusticia testimonial se produce cuando la atribución de credibilidad es efecto de un juicio identitario, ya sea este ajustado o no, con respecto al colectivo al que pertenece la testigo.
Abstract: In this essay, I explain the main claim of Conocimiento expropiado (Broncano 2020) against the background of the agential and reliabilist framework that its author assumes. I then focus on his analysis of situations of testimonial injustice, opposing Miranda Fricker’s approach (focused on prejudice in testimonial exchanges) and Broncano’s one (focused on structural imbalances). By pointing out the shortcommings of both models, I skech an alternative proposal: testimonial injustice is produced when the credibility assessment results from an identity judgment, whether it is effectively appropriate regarding the collective or not.
Palabras clave: Epistemología política, fiabilismo agencial, injusticia testimonial, credibilidad.
Keywords: Political Epistemology, agent reliabilism, testimonial injustice, credibility.
Activismo epistémico y la epistemología del empoderamiento
Authors: Medina José
Published: December 2022

Epistemic Activism and the Epistemology of Empowerment
Resumen: Este artículo argumenta que la teoría de la agencia epistémica compartida de Fernando Broncano llama a un análisis de cómo compartir la agencia epistémica resistente para entender cómo luchar contra los daños epistémicos agenciales en comunidades de resistencia y a través de lo que el autor denomina activismo epistémico. El autor sostiene que la epistemología de la dependencia de Broncano necesita ser suplementada con una epistemología del activismo y del empoderamiento que muestre cómo los daños agenciales epistémicos pueden ser reparados, cómo los obstáculos estructurales e institucionales que constriñen la agencia epistémica de grupos oprimidos pueden ser desmantelados, y cómo la falta de agencia epistémica de grupos marginados puede subsanarse con el empoderamiento epistémico de estos grupos.
Abstract: This article argues that Fernando Broncano’s theory of shared epistemic agency calls for an analysis of how to share resistant epistemic agency in order to understand how to fight against agential epistemic harms in communities of resistance and through what the author terms epistemic activism. The author maintains that Broncano’s epistemology of dependence needs to be supplemented with an epistemology of activism and empowerment that shows how agential epistemic harms can be repaired, how structural and institutional obstacles that constrain the epistemic agency of oppressed groups can be dismantled, and how the epistemic agency of marginalized groups can be restored through the epistemic self-empowerment of those groups.
Palabras clave: Activismo epistémico, agencia epistémica, epistemología de la dependencia, empoderamiento epistémico.
Keywords: Epistemic activism, epistemic empowerment, epistemic agency, epistemology of dependence.
Ciego, sordo y mudo: el sistema sanitario ante la objeción de conciencia al aborto
Authors: Triviño Rosana
Published: December 2022

Blind, deaf, and mute: the healthcare system regarding conscientious objection to abortion
Resumen: A la luz de la obra de Fernando Broncano, Conocimiento expropiado (2020), este trabajo plantea la objeción de conciencia generalizada al aborto como un fenómeno que origina situaciones de injusticia epistémica. El acceso a la información, el disvalor del testimonio de las mujeres y el silencio cómplice, individual e institucional, perpetuador de la ignorancia sistémica son realidades que afectan a un número indeterminado de mujeres que requiere la interrupción de su embarazo. Para hacer frente al daño generado, se plantea cómo las redes y movimientos pro-elección distribuyen información y recursos sobre el aborto fuera del ámbito clínico y se organizan como fuerzas de resistencia epistémica, capaces de crear y compartir conocimiento en un ejercicio de democracia radical, en el sentido expresado por Broncano.
Abstract: In accordance with Fernando Broncano’s work, Conocimiento expropiado (2020), this paper considers the widespread conscientious objection to abortion as a phenomenon that creates situations of epistemic injustice. Access to information, devaluation of women’s testimony, as well as individual and institutional complicit silence that perpetuates systemic ignorance, are realities that affect an indeterminate number of women who require the termination of their pregnancies. In order to address the damage generated, we consider how pro-choice networks and movements distribute information and resources on abortion outside the clinical sphere. They also organise themselves as forces of epistemic resistance, capable of creating and sharing knowledge in an exercise of radical democracy, in the sense expressed by Broncano.
Palabras clave: Objeción de conciencia, aborto, injusticia epistémica, ignorancia institucional, resistencia epistémica.
Keywords: Conscientious objection, abortion, epistemic injustice, institutional ignorance, epistemic resistance.
Testimoniar sometida a la injusticia hermenéutica. Daño sexual y discernimiento
Authors: Martínez-Sáez Carmen
Published: December 2022

Testifying subjected to hermeneutical injustice. Sexual harm and discernment
Resumen: Junto a la concepción del testimonio como institución social sometida a condiciones y normas, hay en Conocimiento expropiado (Broncano 2020) una segunda forma de concebir la práctica epistémica del testimonio que entra en conflicto con la primera y que parece pasar inadvertida. Esta segunda concepción se manifiesta en el modo en que Broncano delimita el acto de testimoniar y la dependencia epistémica. El objetivo de esta contribución es mostrar el conflicto existente entre ambos modos de concebir el testimonio a partir de la tensión interna que presentan: mientras que la concepción del testimonio como institución social nos permite reconocer algunas formas fundamentales de testimonio (a saber, el testimonio de las víctimas de injusticia hermenéutica), las definiciones del acto de testimoniar y de la dependencia epistémica parecen excluirlas. Lejos de invalidar el análisis de Broncano, la tensión interna, aunque problemática para los casos en los que quien testimonia está sometida a la injusticia hermenéutica es, en primer lugar, necesaria para comprender los casos de injusticia discursiva o injusticia testimonial —y, por lo tanto, no defiendo su rechazo?; y, en segundo lugar, pone de relieve la importancia vital de concebir el testimonio como una institución social.
Abstract: Alongside the conception of testimony as a social institution subject to conditions and norms, there arises in Conocimiento expropiado (Broncano 2020) a second way of conceiving the epistemic practice of testimony that conflicts with the first and seems to go unnoticed. This second conception is manifest in the way Broncano delimits the act of testimony and the epistemic dependence. The aim of this contribution is to show the conflict between these two ways of conceiving testimony through the internal tension they present: while the conception of testimony as a social institution allows us to recognize some fundamental forms of testimony (namely, the testimony of victims of hermeneutic injustice), the definitions of the act of testifying and epistemic dependence seem to exclude them. Far from invalidating Broncano’s analysis, the internal tension, although problematic for cases in which the testimonial agent is subject to hermeneutic injustice is, firstly, necessary to understand cases of discursive injustice or testimonial injustice—and, therefore, I do not advocate its rejection?; and, secondly, it highlights the relevance of conceiving testimony as a social institution.
Palabras clave: Testimonio, injusticia hermenéutica, cooperación epistémica, daño sexual.
Keywords: Testimony, hermeneutic injustice, epistemic cooperation, sexual harm.
Music: For a Sustainable Community and the Promotion of Well-being
Authors: Finestrone Francesca
Published: December 2022

This contribution aims to offer food for thought on the ancestral role of music for mankind, considering its potential, transversal to different areas of interest, including psycho-pedagogical, clinical and didactic, as a heterogeneous expression of cultures, communities and characters. In spite of the fact that music education is compulsory in secondary schools, not in all contexts the activities are structured and carried out taking into account the positive implications on pupils’ psycho-physical well-being, rehabilitative potential and increased motivation to learn. Just as the possibilities for dynamics and time in music are manifold, so too is the horizon of options that looms over the sky of educational action, intersecting also with the world of technology, which puts innovative tools such as serious games at the service of education.
Ankle Charcot Mimics: Tubercular Rheumatism to Complex Regional Pain Syndrome
Authors: Rastogi Ashu , Saini Uttam , Jude Edward
Published: December 2022

Charcot Foot is often misdiagnosed because of its varied presentation that mimics other common disorders including tubercular rheumatism, complex regional pain syndrome or gout. We present a case of ankle swelling and discuss the differential diagnosis, radiological findings, and management. We also discuss the approach to diagnosis and provide differences in clinical presentations, magnetic resonance imaging,and bone scan findings for various differentials considered for Charcot foot.
The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)
Authors: Rale Michael J , Romer Brianna , Mahon Brian P , Travis Sophie M , Petry Sabine
Published: December 2022

To establish the microtubule cytoskeleton, the cell must tightly regulate when and where microtubules are nucleated. This regulation involves controlling the initial nucleation template, the γ-tubulin ring complex (γTuRC). Although γTuRC is present throughout the cytoplasm, its activity is restricted to specific sites including the centrosome and Golgi. The well-conserved γ-tubulin nucleation activator (γTuNA) domain has been reported to increase the number of microtubules (MTs) generated by γTuRCs. However, previously we and others observed that γTuNA had a minimal effect on the activity of antibody-purified Xenopus γTuRCs in vitro (Thawani et al., eLife, 2020; Liu et al., 2020). Here, we instead report, based on improved versions of γTuRC, γTuNA, and our TIRF assay, the first real-time observation that γTuNA directly increases γTuRC activity in vitro, which is thus a bona fide γTuRC activator. We further validate this effect in Xenopus egg extract. Via mutation analysis, we find that γTuNA is an obligate dimer. Moreover, efficient dimerization as well as γTuNA’s L70, F75, and L77 residues are required for binding to and activation of γTuRC. Finally, we find that γTuNA’s activating effect opposes inhibitory regulation by stathmin. In sum, our improved assays prove that direct γTuNA binding strongly activates γTuRCs, explaining previously observed effects of γTuNA expression in cells and illuminating how γTuRC-mediated microtubule nucleation is regulated.
The injured sciatic nerve atlas (iSNAT), insights into the cellular and molecular basis of neural tissue degeneration and regeneration
Authors: Zhao Xiao-Feng , Huffman Lucas D , Hafner Hannah , Athaiya Mitre , Finneran Matthew C , Kalinski Ashley L , Kohen Rafi , Flynn Corey , Passino Ryan , Johnson Craig N , Kohrman David , Kawaguchi Riki , Yang Lynda JS , Twiss Jeffery L , Geschwind Daniel H , Corfas Gabriel , Giger Roman J
Published: December 2022

Upon trauma, the adult murine peripheral nervous system (PNS) displays a remarkable degree of spontaneous anatomical and functional regeneration. To explore extrinsic mechanisms of neural repair, we carried out single-cell analysis of naïve mouse sciatic nerve, peripheral blood mononuclear cells, and crushed sciatic nerves at 1 day, 3 days, and 7 days following injury. During the first week, monocytes and macrophages (Mo/Mac) rapidly accumulate in the injured nerve and undergo extensive metabolic reprogramming. Proinflammatory Mo/Mac with a high glycolytic flux dominate the early injury response and rapidly give way to inflammation resolving Mac, programmed toward oxidative phosphorylation. Nerve crush injury causes partial leakiness of the blood–nerve barrier, proliferation of endoneurial and perineurial stromal cells, and entry of opsonizing serum proteins. Micro-dissection of the nerve injury site and distal nerve, followed by single-cell RNA-sequencing, identified distinct immune compartments, triggered by mechanical nerve wounding and Wallerian degeneration, respectively. This finding was independently confirmed with Sarm1-/- mice, in which Wallerian degeneration is greatly delayed. Experiments with chimeric mice showed that wildtype immune cells readily enter the injury site in Sarm1-/- mice, but are sparse in the distal nerve, except for Mo. We used CellChat to explore intercellular communications in the naïve and injured PNS and report on hundreds of ligand–receptor interactions. Our longitudinal analysis represents a new resource for neural tissue regeneration, reveals location- specific immune microenvironments, and reports on large intercellular communication networks. To facilitate mining of scRNAseq datasets, we generated the injured sciatic nerve atlas (iSNAT): https://cdb-rshiny.med.umich.edu/Giger_iSNAT/.
El tejido de la nación: el orden social, la moda y los accesorios en dos novelas de Alberto Blest-Gana
Authors:   Harlaxton College (Inglaterra), Vilches Patricia
Published: December 2022

El ensayo se enfoca en la moda y los accesorios (joyas, muebles, etc.) en dos novelas de Alberto Blest Gana (1830-1920): Martín Rivas (1862) y El ideal de un calavera (1863). Estos son componentes que actúan como objeto de deseo, así como forjadores y guardianes del orden social del Chile decimonónico. Una prenda a la moda, entonces, conecta a alguien con el mundo exterior, lo que indica la aprobación o el rechazo de la sociedad. Desde esta perspectiva, la ropa y los accesorios que usan los personajes de Blest Gana ‘narran’ y articulan luchas, acuerdos, negociaciones, y eventos históricos, a medida que la nación comienza a definirse como tal
El Estrecho de Magallanes y “la región antártica famosa”: aperturas, cierres y desplazamientos en La Antártica y otros mitos de Miguel Serrano
Authors:   Universidad de Magallanes (Chile), Formoso Bavich Christian
Published: December 2022

Las irrupciones inaugurales de Magallanes en la literatura como lugar de paso, y luego de colonización fallida, se articulan sobre la base de una serie de aperturas, cierres, desplazamientos y bloqueos que, aso-ciados a fuerzas naturales descomunales, un mundo indígena giganteo y un culto que termina entregando el control exclusivo del lugar al demonio, terminan produciendo una serie de representaciones funcionales al proyecto político del imperio español del momento, justificando su fracaso en el territorio. Sostengo que La Antártica y otros mitos (1948) de Miguel Serrano, vuelve sobre dichas representaciones del imaginario austral, esta vez desplazadas hacia el Continente Blanco, para hallar en un Magallanes —relegado nueva-mente a lugar de paso ahora en el proyecto nacional—, el nexo entre Chile y la Antártica: mitos y leyendas del pueblo selk’nam, territorio y nazismo, articularán la causa de la nacionalización de los hielos como un deber patriótico, que será refundación, elevación y proyección no solo del ser chileno, sino de Occidente.
Poéticas descolonizadoras: una lectura de Canto general de Pablo Neruda y “Boletín y elegíade las mitas” de César Dávila Andrade
Authors:   Pontificia Universidad Católica de Chile (Chile), Bobadilla Palacios Rodrigo
Published: December 2022

Este artículo propone una lectura de algunas secciones del Canto general (1950) de Pablo Neruda y del poema largo “Boletín y elegía de las mitas” (1959) del poeta ecuatoriano César Dávila Andrade, planteando una reconsideración crítica de ambos textos como la puesta en práctica de dos “poéticas descolonizadoras”. Leídas en el contexto del florecimiento de discursos críticos en torno al paradigma colonial, ambas obras serían emblemáticas del intento por reescribir la historia del capítulo colonial americano, proponiendo una versión a contrapelo que formula una suerte de épica de los vencidos y construye poéticamente un locus alternativo de enunciación que se presta para la recuperación ontológica del sujeto indígena en la escritura. Se revisan algunas ideas de la teoría contemporánea que ha establecido perspectivas críticas al paradigma colonial-moderno (Walter Mignolo y Eduardo Subirats) para demostrar que estas obras de Neruda y Dávila Andrade ya adelantaban en la década de los 50 una interpretación de la “herida colonial” como suceso fundacional del proyecto capitalista-moderno.
Cantos alados en flores de fuego: amores norománticos en Raúl Gardy, Violeta Parra y Víctor Jara
Authors:   Pontificia Universidad Católica de Chile (Chile), Carreño Bolívar Rubí
Published: December 2022

Este artículo explora las relaciones entre pájaros y flores como metáforas, alegorías o ideologemas del erotismo y del amor no-romántico en canciones y poemas de Raúl Gardy (1917-1884), Violeta Parra (1917-1967) y Víctor Jara (1932- 1973). La lectura en conjunto de los tres compositores permite estudiar un tránsito desde propuestas del folclor campesino a una modernidad musical que también incluye los roles de género y los modos de concebir los anchos caminos del amor chileno. Finalmente, se intenta establecer una relación entre naturaleza, género y escritura a partir de las representaciones del amor a través de pájaros y flores.