bluuebunny/crossref_metadata_2025 huggingface dataset:
Сложые эфиры 3-монохлорпропан-1,2-диола (МХПД) и 3-гидрокси-1,2-оксипропанола (глицидола) в жировых продуктах
Authors: А.Н. Лисицын , В.Н. Григорьева , Н.В. Кузнецова
Published: November 2024

Статья представляет собой аналитический обзор литературных источников, посвященных образованию глицидола и 3-МХРПД эфиров в жиросодержащих продуктах. Начиная с 1978 г. этому вопросу посвящено значительное количество работ, и связано как с исследованием факторов, ответственных за образование хлорпропанолов, так и их превращениям в пищевых продуктах, подверженным тепловым обработкам. В статье рассмотрены результаты экспериментальных исследований, установлены основные факторы, способствующие их образованию, прекурсоры и теоретические предложения о химических процессах их образования и данные об их физиологически неблагоприятных свойствах.

The article is an analytical review of literature devoted to the formation of glycidol and 3-MCPD ethers in fat-containing products. Since 1978, a significant amount of work has been devoted to this issue, and is associated both with a study of the factors responsible for the formation of chloropropanols and their transformations in food products that are subject to heat treatments. The article considers the results of experimental studies, establishes the main factors contributing to their formation, precursors and theoretical proposals on the chemical processes of their formation and data on their physiologically unfavorable properties.
Molecular diffusion enhanced performance evaluation of metal-organic frameworks for CO2 capture
Authors: Neumann Barros Ferreira Rodrigo , Joshi Yogesh V. , Lopes Oliveira Felipe , Sundaram Anantha , Mhadeshwar Ashish B. , Kalyanaraman Jayashree , Luan Binquan , Steiner Mathias
Published: November 2024

Molecular diffusion is a fundamental property that limits the performance of solid sorbents in carbon dioxide capture and separation applications. Unique to each sorbent, gas diffusion is determined by the physical and chemical interactions that occur between the gas molecules and a sorbent’s surface atoms. At the process level where carbon dioxide capture performance is validated, however, simulations are typically carried out using generalized parameters that omit the structure-specific, molecular kinetics occurring in each sorbent. Here, we report process-scale simulations of carbon dioxide capture performance in metal-organic frameworks (MOF) informed by molecular adsorption predictions that represent the unique structural properties of each MOF. By evaluating a total of 10,143 MOFs for post-combustion carbon dioxide capture, we demonstrate that the inclusion of the material-specific, molecular diffusion dynamics significantly alters their simulated, process-level performance. Specifically, the inclusion of molecular diffusion relegates up to 20% of the MOF candidates of the initial rank-order while the top 27 MOFs exhibit productivity and energy consumption metrics that surpass those of all known materials used in today’s industrial applications. The method could be applied to evaluate a broader class of solid sorbents, including covalent organic frameworks and zeolites. For validation and reuse, we provide access to data and simulation code.
Cheminformatic Analysis of Core-Atom Transformations in Pharmaceutically Relevant Heteroaromatics
Authors: Bartholomew G. Logan , Karas Lucas J. , Eason Reilly M. , Yeung Charles S. , Sigman Matthew S. , Sarpong Richmond
Published: November 2024

Heteroaromatics are the basis for many pharmaceuticals. The ability to modify these structures through selective core-atom transformations, or "skeletal edits", can dramatically expand the landscape for drug discovery and development. However, despite the importance of core-atom modifications, the quantitative impact of such transformations on accessible chemical space remains undefined. Here, we report a cheminformatic platform to analyze which skeletal edits would most increase access to novel chemical space. This study underscores the significance of emerging single and multiple core-atom transformations in heteroaromatics in enhancing chemical diversity, for example, at a late-stage of a drug discovery campaign. Our findings provide a quantitative framework for prioritizing core-atom modifications in heteroaromatic structural motifs, calling for the development of new methods to achieve these types of transformations.
A point-of-need framework for illicit drug identification with high-resolution mass spectrometry
Authors: Forbes Thomas P , Robinson Elizabeth L , Sisco Edward , Koss Abigail
Published: November 2024

The continually evolving drug landscape, with novel synthetic drugs and unique compositions, necessitates the need to advance technologies, data analysis methods, and data accessibility for compound detection and identification. Providing public health, first responder, and law enforcement communities with critical information in near real-time will aid emergency response and public awareness, and direct overdose prevention and interdiction efforts. A major component of this framework is the progression of accurate drug screening and preliminary identifications from a more rigid laboratory-based arrangement to an agile point-of-need paradigm. We investigated drug detection and identification of a field deployable high-resolution time-of-flight mass spectrometer, employing both acetone-assisted vacuum ultraviolet (VUV) photoionization and dielectric barrier discharge ionization (DBDI) schemes. This preliminary fit-for-purpose exploration was conducted under laboratory conditions, building toward deployment in a mobile laboratory setting. The chromatography-free measurements enabled rapid analysis of neat drug solutions and multi-component mixtures. Characterization and optimization of system parameters demonstrated sensitive performance, with limits of detection in the tens to hundreds of picograms for a range of drug classes from multiple-component mixtures. The system’s high mass resolution was calibrated with a polyethylene glycol calibrant, enabling accurate matching with spectral library entries. Integrating compound identification with the NIST DART-MS Forensics Database and NIST/NIJ DART-MS Data Interpretation Tool provided a solid foundation for transition to the point-of-need. The overarching framework seeks to support technology advancement and adoption, as well as the development of novel data analysis tools, processes, and management for public access and utilization.
Large-scale characterization of chemical bonding and topology in the Materials Project database
Authors: Zoubritzky Lionel , Coudert François-Xavier
Published: November 2024

Topology is key to the determination of many physical and chemical properties of materials, such as electrical and optical properties, magnetic properties, thermal and mechanical behaviour, etc. However, despite the growing number of databases of crystalline materials available, there has been very little systematic effort to date to analyze their topology. In this work, we have leveraged recent algorithmic advances in the analysis of chemical bonding and topology determination in order to perform high-throughput analysis of topology of materials on a large scale databases of existing and hypothetical materials, the Materials Project data set of more than 150,000 structures. Beyond the statistical analysis of the most frequent topologies and coordination environments, the publication of this topological data will allow researchers to search for materials by topology and chemical environment, paving the way to enhanced performance in materials screening for applications. We demonstrated two examples of the usefulness of topological considerations in such computational screening.
Impact of Applied Potential on the Facet Ratio and Size of Ir and Cu Catalysts
Authors: Jayamaha Peshala , Wang Lichang
Published: November 2024

The surface energy of a catalyst material is important for understanding the fundamental behavior of nanoparticles and bulk crystals, particularly in terms of activity, selectivity, durability, and stability. Computational studies of electrocatalysts provide valuable insight into the stability of electrode surfaces under realistic environments, including solid/liquid interfaces. In this work, we model the electrode/solid surface using the density functional theory (DFT), and electrolyte/liquid using the implicit solvation model. Importantly, we examined the surface energies of low-index facets of Ir and Cu crystals in an aqueous electrolyte as a function of applied electrode potential. The results show that each surface facet of the neutral surface belongs to an initial potential which is called the potential of zero charge (PZC). Both Ir and Cu (111) facets have higher PZC values relative to other studied facets. Ir and Cu (111) facets exhibit the most stable surfaces with low surface energy profiles within the range of applied potential, while (110) facets show the lowest stability for electrocatalyst applications. This study shows that the surface energies are highly sensitive to the applied potential and leads to the change in particle size and facet ratio under the applied potentials.
Acidity drives selectivity: tuning reaction pathways under hydrodeoxygenation conditions
Authors: B. Strapasson Guilherme , de Biasi Bafero Gabriel , S. Leite Davi , B. L. Santos Dyovani , Albuquerque Ângela , D. Barcelos Ingrid , M. Rossi Liane , B. Rodella Cristiane , Zanchet Daniela
Published: November 2024

The design and tuning of active sites (e.g., metallic, acid, and redox sites) are crucial for developing active, selective, and stable catalysts. Metal-support interactions (MSI) and the creation of interfacial sites can tailor the catalytic performance of metal/oxide catalysts for various reactions, directly impacting C-O, C-C, and C-H bond activation and H2 spillover. By modulating the acidity of the support (i.e., Brønsted-rich or Lewis-rich), we elucidate the role of acid sites over the acetone hydrodeoxygenation reaction pathways. Brønsted-rich catalysts favor the formation of selective C-O bond cleavage products, whereas Lewis-rich catalysts favor C-C coupling + C-O bond cleavage cascade products. We demonstrate that tailoring active sites from the support and constructing active metal-oxide interfacial sites can tune the catalytic performance toward targeted reaction pathways with enhanced stability. Our findings provide insights into C-O, C-C, and C-H bond activation, cleavage, and coupling that can be expanded to multiple catalytic reactions, contributing to the development of new functional materials with enhanced performance.
Microelectrode Arrays for Electrochemical Cycling of Individual Battery Particles
Authors: Suk Wonjoon , Min Jinhong , Liu Tongchao , Li Yiyang
Published: November 2024

The electrochemical characterization of battery materials is usually performed on porous electrodes containing conductive additives, binders, and ensembles of redox-active particles at densities as high as 10^15 / cm^3. These complex structures often obscure individual battery particles' intrinsic properties, hindering insights into the fundamentals of battery electrochemistry. To address this challenge, we developed microelectrode arrays to enable the charge and discharge of individual battery particles in liquid electrolytes. In this Methods and Protocols paper, we describe the fabrication of the microelectrode array chips, the assembly of particles onto microelectrodes, and the different types of electrochemical techniques that can be used, including galvanostatic cycling, cyclic voltammetry, potentiostatic intermittent titration, and electrochemical impedance spectroscopy. We use micron-sized lithium cobalt oxide as a model system to showcase the reliability and versatility of single-particle electrochemical experiments enabled by our microelectrode array. We aim to provide a detailed description to promote future uses of microelectrode arrays in fundamental research of batteries and other electrochemical systems.
Stacked all-graphite microfluidic microbial fuel cells
Authors: Liu LInlin , Bansept Marc-Antoine , Cao Changhong , Boudreau Denis , Greener Jesse
Published: November 2024

In this work, three high-surface-area graphite plates were structured by micromilling and incorporated directly microfluidic microbial fuel cells. All MFCs were run individually to verify their high-power outputs and substrate conversion efficiencies. Then the MFCs grew electroactive biofilms with an average 35 µm thickness. They were connected in different stacked configurations to increase raw outputs. In a parallel configuration, the internal resistance was as low as 480 Ω, resulting in outputs in power (595 µW) and current (1.4 mA), which are impressive by microfluidic standards. Adjusting the flow conditions enabled the parallel stack to reach over 70% acetate utilization. A series stack was used to successfully power an environmental multisensor (temperature, humidity) and a wristwatch. We discuss staked systems that could reproduce the results of an 850 L pilot MFC system.
Identification of phosphatases that dephosphorylate the co-chaperone BAG3
Authors: Kokot Thomas , Zimmermann Johannes P , Chand Yamini , Krier Fabrice , Reimann Lena , Scheinost Laura , Höfflin Nico , Esch Alessandra , Höhfeld Jörg , Warscheid Bettina , Köhn Maja
Published: November 2024

The co-chaperone BAG3 plays critical roles in maintaining cellular proteostasis. It associates with 14-3-3 proteins during the trafficking of aggregation-prone proteins and facilitates their degradation through chaperone-assisted selective autophagy in cooperation with small heat shock proteins. Although reversible phosphorylation regulates BAG3 function, the involved phosphatases remain unknown. Here, we used affinity purification mass spectrometry to identify phosphatases that target BAG3. Of the hits, we evaluated the involvement of protein phosphatase-1 (PP1) using chemical inhibitors and activators in in vitro and cellular approaches. Our results demonstrate that PP1 can dephosphorylate BAG3-pS136 in cells and counteract 14-3-3γ association with BAG3 at this motif. Furthermore, protein phosphatase-5 (PP5) co-enriched with proteostasis-related proteins, and it has the capacity to dephosphorylate a BAG3 phosphorylation-site cluster regulating the interaction of BAG3 with small heat shock proteins and BAG3-mediated protein degradation. Our findings provide new insights into the regulation of BAG3 by phosphatases. This paves the way for future research focused on the precise control of BAG3 function through its regulatory proteins, potentially holding therapeutic promise for diseases characterized by disrupted proteostasis.
Enhancing e-government in digital transformation: integrating archive management and digital solutions in Pekanbaru, Indonesia
Authors: Rahman Khairul , Adni Dita Fisdian , Nasution M Ari Tri Putra
Published: November 2024

Efficient and modern archive management is very important in this digital era, especially at the local government level. In this context, this study explores the urgency of archive management using the Integrated Dynamic Archival Information System (SRIKANDI) approach in the Pekanbaru City Government. The research method used is qualitative, with data sources from interviews, documentation, and observation and analysis using the NVivo 12 Plus software. The study's results identified challenges to SRIKANDI implementation, including inadequate technological infrastructure, the need for skilled human resources in information technology, attention to data security, changes in organizational culture, and ongoing technical support. Based on these findings, policy recommendations have been made, including investments in technology infrastructure, human resource training and development, strict data protection, and changes in organizational culture. This research has positive implications for archive management, increasing efficiency and accountability in Pekanbaru. This research provides insights for other city governments wishing to undertake similar digital transformations in electronic-based archives management
Bridging the digital divide: analyzing public participation in Indonesia's e-government through the e-participation index
Authors: Nurhidayat Nurhidayat , Nurmandi Achmad , Congge Umar
Published: November 2024

This study explores the level of public participation in e-government in Indonesia, focusing on the Electronic Participation Index (EPI). This research uses qualitative methods and qualitative content analysis. The main data was obtained from the UN E-Government Knowledgebase, especially the E-Participation Index for 2016 to 2022 and Indonesia's E-Participation Index ranking data from 2004 to 2022. The results of this study show that the improvement of e-government infrastructure and services has not been fully successful in increasing public participation. The challenges faced include inadequate regulations, lack of data integration, gaps in ICT infrastructure, and inequality in internet access, especially in rural areas. The culture of bureaucracy, corruption, collusion, and nepotism also hinder public trust in the e-government system. Some government initiatives, such as the Peduli Lindungi application, have shown positive results but have not been fully optimal. To overcome these challenges, it is necessary to improve regulations, integrate data, reduce the digital divide, and increase government transparency and accountability. What is new about this study lies in its comprehensive analysis of the E-Participation Index in the Indonesian context, which provides a unique perspective on the correlation between e-government infrastructure and public participation levels. In addition, the study offers actionable insights and recommendations for policymakers to improve e-government services by addressing specific regional and cultural barriers.
International organisations on national politics: Council of Europe effects on political party in Turkiye
Authors: Kahraman Selçuk , Kutlu Önder
Published: November 2024

This paper intends to examine influence of the Council of Europe (CoE) in two major political parties of Turkiye through their election manifests during the first quarter of the 21st century. The ruling AK Parti and main opposition party, CHP, election manifests are reviewed via MAXQDA data analysis panel. As one of the founding member states of the Council Turkiye has got close ties with the organisation and this has impositions on the national politics. This being the case, the problem of how this area is put on the agenda and evaluated in terms of Turkish political life becomes important. The effects of the CoE on Turkish political parties are classified under eight headings. These headings are examined with the help of graphics as 8 subcategories: “law”, “fundamental rights and freedoms”, “foreign policy”, “public administration”, “fight against corruption”, “democracy”, “labour and social security” and “family and social policies”. Among these, “law” and “fundamental rights and freedoms” categories stand out as the most emphasized issues in the context of the CoE for both parties. Finally reveals that CHP and AK Parti priorities or emphases diverge on certain issues related to CoE. Thus, family and social policies for the CHP, and foreign policy and the fight against corruption for the AK Parti have defined the more prominent categories. Having examined the effects of the Council the paper draws a clear line of relations as far as the eight categories are concerned.
FACTORS INFLUENCING THE DETERMINATION OF AUDITORS' FEES IN ALGERIA (FROM THE PERSPECTIVE OF PROFESSIONALS) - AN EMPIRICAL STUDY USING DEMATEL ANALYSIS
Authors: Belkacem Boufatah , Abdallah Bensafiddine
Published: November 2024

Objective: This study aims to identify the factors influencing the determination of auditors' fees in Algeria from the perspective of the practitioners, by understanding the relative importance of these factors.
 
Theoretical Framework: The theoretical aspect addressed the most important factors influencing the determination of auditors' fees in Algeria, which are: the duration of the audit process, the size of the audited institution, the reputation and fame of the audit office, the quality of the audit office, and the risks of the audit process.
 
Method: In order to determine the interrelationship between the influencing factors that contribute to the determination of auditors' fees in Algeria, the "DEMATEL" method was used, which relies on the opinions of experts (audit experts). Mathematical techniques represented in matrices were employed to identify the most influential factor among the following: the duration of the audit process, the size of the audited institution, the reputation and fame of the audit office, the quality of the audit office, and the risks of the audit process.
 
Results and Discussion: Through the cause-and-effect relationship, the study concluded that the "reputation and fame of the auditing office" is the most important perspective for evaluation with the highest impact value (5.942), while the "audit process risk factor" is the least important perspective with an estimated value of (4.392), in order to reach the appropriate input for determining the fees of auditors in Algeria.
 
Research Implications: The study results highlight the importance of the factors influencing the determination of auditors' fees in Algeria. As it is necessary to understand the degree of influence of each criterion in determining these fees, and consequently to identify the necessary solutions to reach a unified model for fees in Algeria based on the influencing factors, instead of subjecting the fees of auditors in Algeria to the method of specifications.
 
Originality/Value: This study contributes to the literature on the factors influencing the determination of auditors' fees in Algeria by providing empirical evidence from Career experts in Algeria and analyzing it using mathematical methods to identify the most significant influencing factors, enabling policymakers to formulate the necessary policies.
INNOVATIVE TRIAD: RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF LEVOSALBUTAMOL SULPHATE, AMBROXOL HYDROCHLORIDE AND GUAIPHENESIN IN ORAL LIQUID DOSAGE FORM
Authors: M. Selvakanimozhi , M. Archana
Published: November 2024

Levosalbutamol Sulphate, Ambroxol Hydrochloride, and Guaiphenesin together provide a comprehensive approach to the treatment of different respiratory disorders, symptom relief, and improved respiratory health. RP-HPLC has become a highly effective method with great resolution, sensitivity, and repeatability for analyzing complex mixtures. This paper describes the development and estimation of the RP-HPLC approach for the concurrent quantification of guaiphenesin, ambroxol hydrochloride, and levosalbutamol sulphate in bulk and medicinal dose form. The chromatographic separation was performed with HPLC agilent 1100 series with DAD detector, EZ Chromelite software was used for the chromatogram identification. The stationary phase used was C-18 inertsil column of dimension 250 × 4.6 mm with particle sizes of 5µ. The mobile phase used was buffer, acetonitrile and methanol in the ratio of (65:10:25). The developed method produced chromatogram with perfect sharp peaks, and with good resolution and minimal tailing. The retention time of Levosalbutamol sulphate, guaiphenesin and ambroxol hydrochloride was found to be 2.853, 8.273 and 12.273 respectively. The method was linear with the correlation coefficient value of 0.9999. The system suitability parameters were found to be within the acceptable criteria. In summary, we have developed a robust analytical approach that can reliably and accurately quantify these active components through rigorous method development and validation procedures. The findings of the technique validation, carried out in compliance with ICH principles, have shown that the approach is suitable for routine quality control analysis and that the results fall within acceptable bounds.
BARRIERS AND BENEFITS OF TECHNOLOGY INTEGRATION IN EDUCATION: PERSPECTIVES FROM HIGHER SECONDARY STUDENTS
Authors: Gnana Jothi J  , D. Ponrani
Published: November 2024

This study explores the barriers and benefits of technology integration in education from the perspectives of higher secondary students in Kanyakumari District. It highlights how technology has transformed learning environments, enabling access to a vast array of resources and interactive learning tools. The research identifies key benefits, such as enhanced engagement, personalized learning experiences, and improved digital literacy, which are essential in the modern educational landscape. However, it also uncovers significant barriers, including inadequate infrastructure, lack of teacher training, and resistance to change among both educators and students. These obstacles hinder the effective implementation of technology in classrooms. By utilizing qualitative methods, including surveys and interviews, this study aims to provide insights that can inform policy recommendations and strategies for enhancing technology integration in local educational institutions, ultimately fostering a more conducive learning environment for students in Kanyakumari District. Both primary data and secondary data has been collected. Simple random sampling method was used to gather 200 respondents has been used from Kanyakumari District in order to obtain the relevant data.
AN EMPIRICAL STUDY OF AI MECHANISM AS MARKETING TOOL FOR FMCG PRODUCTS
Authors: M G Lakshmipathaiah
Published: November 2024

This study explores the impact of AI mechanisms as marketing tools for FMCG products in India, focusing on consumer engagement, personalization, and sales growth. Using a descriptive research methodology, data was collected from 200 managers and executive-level employees in Mysuru City through structured questionnaires. The findings revealed that AI significantly enhances consumer engagement, personalization, and customer satisfaction, improving marketing efficiency. However, its effects on brand loyalty and market penetration were less significant. Based on these results, it is suggested that FMCG companies strategically integrate AI to optimize marketing strategies, continuously innovate, and adapt to maintain a competitive edge and meet evolving consumer expectations.
Functional status of the cardiovascular system in elderly patients with sarcopenia
Authors: Samoilova Iu. , Matveeva M. , Podchinenova D. , Yakimova Ya. , Shuliko L. , Avkhimenko V. , Kudlay D. , Samoylov E. , Khoroshunova E. , Ragimov A.
Published: November 2024

Sarcopenia is a pathological condition found in elderly patients that impairs their quality of life and increases the risks of disability. Objective. To assess the functional state of the cardiovascular system in elderly patients with sarcopenia. Materials and methods. The main group included patients with sarcopenia diagnosed according to the criteria of EWGSOP-2 (European Working Group on Sarcopenia in Older People 2) supplemented by the screening questionnaire SARC-F (Strength, Assistance with walking, Rising from a chair, Climbing stairs and Falls). The state of the cardiovascular system was assessed based on the results of ECG, echocardiography and duplex examination of vessels at rest. Results. The features of the functional state of the cardiovascular system in sarcopenia were determined, which manifested themselves in the form of impaired repolarization processes and arrhythmic dysfunction, lower parameters of cerebral perfusion, and the presence of an early sign of latent heart failure. Conclusions. The treatment of cardiovascular diseases in the elderly population requires special attention due to the polymorbidity of patients and sarcopenia should be taken into account, among other things, as a factor affecting the state of the cardiovascular system.
Clinical case of the development of lipoid pneumonia due to diesel fuel poisoning
Authors: Smirnov A. , Mikhailov A. , Velibekov R. , Shevchenko A. , Bugorskii I.
Published: November 2024

Treatment of severe pneumonia, including lipoid pneumonia (with the addition of a bacterial infection), is an urgent health problem and requires adherence to an algorithm of clinical and diagnostic measures to ensure adequate treatment tactics. Late admission to the intensive care unit for severe community-acquired pneumonia has been associated with high mortality rates. A clinical case is presented of a patient who received diesel fuel poisoning as a result of violation of safety requirements when working with technical fluids. Indicators of blood gas composition during the development of respiratory failure are presented, as well as options for the development of complications in the form of parapneumonic pleurisy, severe bilateral polysegmental pneumonia with areas of tissue destruction and the formation of pneumofibrosis. Complex antibacterial, detoxification, mucolytic, analgesic, gastroprotective oxygen therapy and insulin therapy were carried out. Timely comprehensive treatment allowed us to achieve a favorable outcome.
El pulque: una perspectiva desde los agronegocios
Authors: Fernandez-Galicia Yessica Viridiana , Sagarnaga-Villegas Leticia Myriam , Salas-González José Maria , Portillo-Vázquez Marcos
Published: November 2024

El pulque es una bebida alcohólica fermentada originaria de México, proviene de la fermentación del aguamiel extraído del Agave salmiana y de otras especies, su explotación se concentra en la región centro de México. En los últimos años, su consumo se ha incrementado debido a una mayor valorización de la identidad nacional y por su carácter natural libre de conservadores. El aumento en el consumo ha incentivado a los agricultores a invertir en la plantación de esta variedad de agave. Sin embargo, existe literatura científica limitada sobre la rentabilidad de esta actividad productiva. Está investigación contribuye a identificar la rentabilidad del cultivo a través de estimar costos de producción e ingresos de una Unidad Representativa de Producción ubicada en Coatepec, Ixtapaluca, México. La información se colectó a través de paneles de productores en el año 2021, los datos se procesaron conforme a la metodología de la Asociación de economistas agrícolas de Estados Unidos, adaptada para México. La producción de pulque en las condiciones y región descritas es un agronegocio rentable, principalmente por el nivel de integración de la cadena de producción, bajos costos de transacción y venta en canales cortos de comercialización, se recomienda ampliar los estudios económicos en otras zonas pulqueras y evaluar competitividad.
Projeto Experimental Agência Virtus: Laboratório SER
Authors:   , Silveira Larissa Ferreira Pedrozo
Published: November 2024

No decorrer do Projeto Experimental – PEX, que se trata da criação de uma agência
de publicidade, composta por alunos e orientada por uma professora, com o objetivo de criar
uma vivência do mercado de trabalho, os alunos que compõem a Agência atende um cliente
real, com demandas reais e com isso cria-se um projeto de pesquisa acadêmica. A agência
criada recebeu o nome “Virtus”, do latim virtude, a Agência é composta por cinco acadêmicos
ocupando as funções de: criação – Larissa Pedroso, marketing e mídias digitais – Márcio
Ferreira, atendimento – Priscila Fernandes, redação – Renan Junior e planejamento – Sarah
dos Santos. No decorrer do texto a agência discorre sobre o cliente, seus produtos e serviços,
bem como colocação no mercado e concorrência, realiza-se pesquisas e análises que compõe
os dados e propostas aqui apresentados.
Foram aplicadas as matrizes SWOT, para levantar as forças e fraquezas, ameaça e
oportunidades do cliente, o Laboratório SER. Também foi aplicada a matriz os 4P's do
marketing tradicional ou mix de marketing, para identificar os aspectos de Preço, Praça,
Produto e Promoção, por último foi feita a análise da concorrência usando as 5 forças de
Porter.
O Laboratório SER surgiu quando tornou-se evidente a difícil realidade de adaptação
à Lei Nº 10.639/03 vivida pelas escolas brasileiras do ensino regular. A complexidade no
desenvolvimento de propostas para a melhoria do conteúdo educacional Afro-Brasileiro,
assim como, na aquisição de materiais de apoio ao ensino, motivaram a criação do
Laboratório Ser, que por sua vez, proporciona a experiência informativa sobre a cultura e
história Afro-Brasileira através de produtos e serviços exclusivos, com o intuito de promover
a diversidade, representatividade e instrumentos para a efetivação da Lei criada em 09 de
janeiro de 2013.
Análisis automático de cartas de postulación laboral en dos fases del proceso de escritura: Exploración de las potencialidades de Trunajod.
Authors:   , DAZA BOTERO CLAUDIA ELENA
Published: November 2024

En esta investigación, se busca explorar la capacidad de Trunajod para evaluar la calidad de la escritura de cartas de postulación laboral, a la luz de los índices léxicos, semánticos y sintácticos de la herramienta. Además, se pretende determinar si existe un impacto o comportamiento diferente en la calibración metacognitiva en virtud de las distintas fases de la escritura por persona y los resultados de las comparaciones entre cada grupo de análisis. El impacto potencial de esta investigación en el campo del procesamiento del lenguaje natural y la lingüística computacional es sustancial ya que refleja, a través del uso de la herramienta, una integración real de los procesos intrínsecos de la escritura propios de un escritor con mayor competencia que los agentes de Recursos humanos podrán aprovechar en los procesos de selección.
En el estudio, los participantes (51, la mayoría entre los 21 y 30 años) debían escribir una carta de postulación laboral en dos fases (primero borrador, luego versión final) a través de un formulario de Google cuyos resultados se analizaron con una rúbrica manual de 8 índices validada por dos evaluadores, junto con el software Trunajod y sus 72 índices de evaluación.
Con las muestras que se obtuvieron, se aplicaron análisis estadísticos que permitieron comparar las variables de Trunajod con las revisiones manuales para determinar la idoneidad de la herramienta como instrumento de calificación objetivo para este tipo de textos específicos; además, las observaciones nos permitieron detectar si se dieron diferencias significativas en las que se hubiera reflejado el trabajo metacognitivo de regulación implementado.
Los resultados demostraron que Trunajod es una herramienta de evaluación que, de forma objetiva, analiza las habilidades presentes en la escritura de cartas de postulación laboral a través de índices que discriminan características relevantes de la producción escrita para los desempeños de un mismo grupo.
Con respecto a la calibración metacognitiva, los resultados dan cuenta de un buen ejercicio de monitoreo de los procesos de escritura de cada sujeto para los análisis entre los mismos tipos de grupos textuales: borradores con desempeño alto vs. borradores con desempeño bajo y textos finales con desempeño alto vs. textos finales con desempeño bajo.
Las perspectivas de las fotógrafas en el estallido social de octubre del 2019 en Concepción de Chile.
Authors:   , FUENTES ASTUDILLO VICTORIA ANDREA
Published: November 2024

La presente investigación tiene por objetivo interpretar las perspectivas de las fotógrafas en la producción profesional de hechos históricos, en específico, el estallido social del 2019 en Concepción, desde el enfoque feminista. El propósito es estudiar la visión de las fotógrafas que producen archivo, identificando y analizando los diferentes componentes que ellas presentan acerca del hecho en cuestión, estableciendo relaciones entre ellas y otras fuentes de información.
La fotografía con enfoques feministas ha introducido la voz y la mirada de las mujeres, antes invisibilizadas por el patriarcado, y busca desconectarlas del rol tradicional que se les ha impuesto a lo largo de la historia, en este sentido, tiene relación con los derechos humanos, con la autodeterminación de cuerpos y territorios.
La metodología utilizada es de tipo no probabilística y el muestreo es por propósito, centrada en mujeres fotógrafas profesionales, cuyas publicaciones estén centradas en el estallido social y se identifiquen con el feminismo. Este último punto será trabajado por medio de entrevistas y el material visual será analizado bajo sus propios criterios considerados a su vez como hallazgos de la investigación. Por esta razón, la estrategia de recolección de datos es crear una narración en conjunto con las participantes.
A través de esta investigación se pretende identificar la producción de cuatro fotógrafas feministas y analizar su expresión crítica en torno a los temas claves presentes en las manifestaciones y el cómo interpelan al espectador respecto del estallido social de octubre del 2019, desde la mirada feminista.
Análisis de la interacción entre la operación de parques solares y eólicos y los sistemas de distribución de plantas mineras.
Authors:   , Gálvez Cabrera Yuyuniz Aline
Published: November 2024

La integración de energías renovables, particularmente solar y eólica, se ha convertido en un factor crucial en la generación eléctrica en Chile, con una notable concentración de parques en el Desierto de Atacama. Estos parques comparten líneas de transmisión y subestaciones con grandes complejos mineros, cuyos sistemas eléctricos enfrentan desafíos significativos debido a la alta presencia de cargas no lineales, y su sensibilidad a perturbaciones en el voltaje. En esta tesis se investiga cómo la operación de parques eólicos y solares de alta potencia conectados cerca de complejos mineros afecta la estabilidad y la calidad del suministro eléctrico de los sistemas de distribución. Este trabajo se enfoca en la regulación del voltaje, la frecuencia y la operación dinámica durante cortocircuitos. Se utiliza la herramienta de simulación PowerFactory de DIgSILENT para modelar una planta minera y su conexión al sistema eléctrico nacional, incluyendo la interconexión con parques eólicos y solares. El modelo considera diferentes tecnologías de turbinas eólicas de conversión directa y de doble alimentación, y se somete a pruebas bajo un escenario de alta demanda durante un día laboral. Las simulaciones evalúan cinco contingencias específicas, como cortocircuitos trifásicos y desconexiones de carga. El principal aporte de este trabajo es evaluar el comportamiento de los parques eólicos y fotovoltaicos durante cortocircuito, y su efecto en la calidad del suministro eléctrico de los sistemas de distribución mineros que se conectan en a las mismas subestaciones y/o líneas de transmisión. Los resultados muestran que los modelos de parques WECC y PowerFactory analizados son capaces de mantener la estabilidad del sistema eléctrico ante diferentes contingencias, lo que confirma la viabilidad de esta integración para garantizar un suministro eléctrico confiable y estable en entornos críticos como los sistemas industriales mineros. Por otro lado, la generación renovable puede causar inestabilidad en el sistema eléctrico en caso de desconexiones inesperadas cuando su aporte es significativo, afectando la calidad del suministro eléctrico y los procesos mineros. Esta investigación destaca la necesidad de desarrollar regulaciones internacionales específicas para manejar estos desafíos y asegurar una integración efectiva de energías renovables en sistemas mineros.
Modeling of Archean Earth-like aquaplanets atmospheres: the effect of obliquity on habitability and observables of exoplanets.
Authors:   , González-Vidal Benji S. E.
Published: November 2024

La búsqueda y observación de exoplanetas habitables similares a la Tierra, así como la interpretación de estas observaciones, se han convertido en temas centrales de la astronomía actual. Nuestro objetivo es investigar la interacción entre la oblicuidad planetaria, la termodinámica atmosférica y los procesos hidrológicos, y su impacto en la habitabilidad y las propiedades espectroscópicas de los acuaplanetas con una composición atmosférica similar a la de la Tierra Arcaica. Utilizando un modelo de circulación general (GCM) y modelos de transferencia radiativa (RT) para simulaciones atmosféricas y de espectros de emisión, modelamos diez acuaplanetas con atmósfera similar a la de la Tierra Arcaica con oblicuidades variables. La habitabilidad se analiza a través de la temperatura de la superficie del mar (TS) y la temperatura del bulbo húmedo (TW). Se analiza el espectro de emisión para determinar los cambios debidos al efecto de la oblicuidad. Nuestros resultados confirman que la oblicuidad influye significativamente en su termodinámica atmosférica, la habitabilidad de la superficie y los espectros de emisión observables para el caso sin nubes. En particular, los rasgos de absorción de vapor de agua de 2.7 y 6.0 µm en escenarios sin nubes se correlacionaron con TW para oblicuidades mayores o iguales a 52.5o. Nuestros hallazgos proporcionan información sobre las posibles características climáticas y espectrales de las atmósferas de tipo Arcaico relacionadas con la oblicuidad, ofreciendo una base para interpretar las observaciones de exoplanetas. Estos resultados podrían servir de base para futuras misiones telescópicas y contribuir al desarrollo de métodos para estimar la oblicuidad y la habitabilidad de exoplanetas a partir de datos espectroscópicos.
Efectos de la edad y del nivel de educación formal en la comprensión lectora de personas mayores.
Authors:   , GUTIÉRREZ ZENTENO GLORIA ANGÉLICA
Published: November 2024

Este estudio busca contribuir al conocimiento sobre el comportamiento cognitivo y lingüístico en adultos mayores, específicamente en relación con la comprensión lectora. Se pretende profundizar en este tema desde una perspectiva psicolingüística. El problema de investigación se centra en dos preguntas fundamentales: ¿El nivel de educación formal alcanzado influye en el desempeño en comprensión lectora en la vejez? ¿Es posible distinguir grupos de tercera y cuarta edad en base a su desempeño en comprensión lectora?. El estudio se llevó a cabo a través de la aplicación de una prueba de comprensión lectora a adultos mayores de tercera y cuarta edad. Se analizaron variables como el nivel de escolaridad, la edad y el desempeño en la prueba. Los resultados mostraron que el nivel de escolaridad influye positivamente en el desempeño en comprensión lectora en adultos mayores. Además, se encontraron diferencias en el desempeño entre los grupos de tercera y cuarta edad, aunque estas diferencias no se explicaron completamente por variables como la edad y la escolaridad.
En conclusión, este estudio demostró que el nivel de educación formal alcanzado tiene un impacto en la comprensión lectora en adultos mayores. También se encontraron diferencias en el desempeño entre los grupos de tercera y cuarta edad. Sin embargo, existen limitaciones en la muestra y en el instrumento utilizado, lo que sugiere la necesidad de futuras investigaciones en este campo.
Aesthetic crown lengthening in gingival enlargement patients with orthodontic treatment: A case report
Authors: Shalahuddin Maulidi  , Aqila Alfakhry  , Antonius Lucky Arnando  , Agung Krismariono
Published: November 2024

Introduction: The orthodontic treatment process that is carried out can cause changes in the soft tissue and hard tissue of the tooth support and the most common is the enlargement of the gingiva. One of the managements in the case of gingival enlargement is crown lengthening, which is carried out by taking gingival tissue with or without bone reduction to further expose the tooth structure so that a better ratio of dental crown and gingiva is obtained. The purpose of this article is to describe the crown lengthening procedure with bone reduction to correct excessive gingival display in patients with orthodontic treatment on the anterior teeth of the upper jaw Case Report: A 19-year-old female patient came to the Periodontology Specialist Poly on a referral from the Dental Orthodontic Specialist of RSGM Universitas Airlangga with complaints that the upper front teeth looked shorter. The patient does not have problems with the periodontal tissue and has no history of systemic diseases such as diabetes, high blood pressure, and no history of allergy to medications. Case management: After the analysis is carried out on the periodontal tissue, the therapy option is in the form of crown lengthening with bone reduction for the treatment of the case. Conclusion: Determining etiological factors and proper examination is very important to determine a crown lengthening action plan as the elimination of gingival enlargement so that it can improve aesthetic appearance.
Potassium, sodium, and proximate analysis of steamed sponge cake from durian seed flour (Durio Zibethinus)
Authors: Irwan Said  , Purnama Ningsih  , Ni Made Ayu Astuti  , Elissandra Bange  , Hardianti Hardianti
Published: November 2024

Steamed sponge is a conventional cake that enjoys widespread popularity and is highly cherished by the general population. The cake is commonly made using wheat flour. Given the present increase in demand for wheat flour, an alternative option for making steamed cakes is to utilize durian seed flour instead of additional wheat flour. Durian seed flour, which has excellent nutritional value for health, is made from processed durian seeds. This study aims to find out how much potassium and sodium are present in steamed sponge cake based on durian seed flour and to ascertain the quantities of fat, protein, and carbohydrate. Atomic absorption spectrophotometry was used to determine the levels of potassium and sodium in steamed sponge cake. The sodium levels were analyzed at a specific wavelength of 766.5 nm, whilst the potassium levels were analyzed at a distinct wavelength of 589 nm. The proximate analysis involves determining the protein content using the micro-Kjeldahl method, the fat content using the soxhletation method, and the carbohydrate content using the UV-VIS spectrophotometry method at a wavelength of 460 nm. The study found that steamed sponge cake contains approximately 44% carbohydrates, 28% protein, and 23% fat in terms of its nutritional composition. Furthermore, the potassium concentration measured 284 mg per 100 grams, whereas the sodium value was 62 mg per 100 grams.
Navigating laboratory investigations for an accurate assessment of community-acquired pneumonia: Case report
Authors: Yamini Sivakoti  , Aleena Roy
Published: November 2024

According to recent findings, demographic characteristics, seasonal fluctuations, and geographic regions are factors for the community-acquired pneumonia. Community acquired pneumonia is a non-hospital acquired lung parenchymal infection caused by gram-negative bacteria “Pseudomonas aeruginosa” which is transmitted through inhaling infected droplets. Here, we are reporting a case of geriatric patient with chief complaints of cough in the past 20 days, shortness of breath, tachycardia, tachypnoea, fever, and chest pain from 10 days. physician was suggested go for further investigations and lab reports like complete blood picture count, ESR test, sputum culture test and radiographic findings like Chest X-ray, chest computed tomography. Standard treatment includes antibiotics like Levofloxacin, Azithromycin and antihypertensive like Telmisartan, and mucolytics like Ambroxol syrup and other medications like N-Acetyl Cysteine, levocetirizine. If early diagnosis and early treatment were initiated, then the progression of diseases would have been stopped and then the Patient was discharged with stable condition, but she must come for the follow-up sessions like OP sessions. If the patient follows the life-style modifications and precautions like practice good hygiene, take enough rest, consume healthy diet, the quality of life will be improved.