bluuebunny/crossref_metadata_2025 huggingface dataset:
A Deep Fake Detection System Using Diffusion Model Based on Graph Based Image Segmentation
Authors: Al-Din Basim Najim , Jaber Karimpour , Mahan Farnaz
Published: November 2023

With the development of technology and the increase in the need to use the internet and the transmission of personal data and save it on the cloud and personal computers and with the increase in security risks represented by penetrations and cyber threats, and among these threats are those represented by the use of deep learning techniques to produce deep fake images that are mostly used to violate cyber security through threats such as the ransom threat or publishing fake news and other cyber risks, so there was an urgent need to establish systems to detect deep forgery in images or videos, in this paper a system was proposed to detect deep forgery based on the principle of using the diffusion model based on the graph based on image segmentation where the system transforms the image to graph and then segment it into three areas which are fake, real and background. And do purification of the adversarial content in these areas using diffusion technology, and then identify the fake areas in the image and use GCN in order to distinguish between real and fake images. In order to evaluate the proposed method, it was compared with the other methods on different data sets (CELEB-DF (V2) data set, Face Forensics++ data set, and wild deep fake). The result shows that the proposed system achieved better results than the approaches in the literature.
A New Method for Human Activity Recognition of Photoplethysmography Signals Using Wavelet Scattering Transform
Authors: Wang Ziyu , Liu Feifei , Xia Shengxiang , Shi Shuhua , Wang Lin , Xu Zheng , Ai Sen , Huang Zhengyong
Published: November 2023

Exercise is an indispensable part of people’s lives and is closely related to their health. Human Activity Recognition (HAR), which involves detects and analyzes human body activity, has become the focus of current research. Photoplethysmography (PPG) has advantages such as convenience for detection and low cost, and is widely used in wearable devices becoming an ideal choice for HAR. In this study, we used wavelet scattering transform (WST) to extract features from PPG and then performed activity recognition on it. We achieved excellent classification accuracy of 92.54% and 97.76% respectively in the experiments of three-class and four-class exercise detection. The results showed this method based on wavelet scattering transform and PPG can accurately detect exercise types and provide effective support for HAR.
Identifikasi Kebutuhan Bahasa Inggris Bagi Mahasiswa Teknik Sipil Politeknik Negeri Semarang
Authors: Sulaiman Sri Wahyuningsih , Suroso Suroso , Wahyumi Puji , Mahmudi Wildana Latif , Yusetyowati Yusetyowati
Published: November 2023

The goal of Semarang State Polytechnic is to produce skilled and professional graduates as middle expert technicians who have integrity, high self discipline, high responsibility and good proficiency of English skill for communication. In order to achieve the goal, it needs a good quality of curriculum which matches with industrial needs. To obtain empirical data to validate the English Language needs and skills, this research was done, and designed as a survey to achieve two aims: a).To identify the English language  skills are needed by civil engineering graduates to perform in the work environment. b).To identify the topics of ESP which are most required by the civil engineering graduates in their work environment. It was found that the English language skills which are most required by graduates in the work environment is speaking skill followed by the listening, reading and writing respectively, the speaking skill is to communicate with customers and consultants. The reading skill is to read contract document, tender calculation, specification of project work, instruction and writing skill is to write tender project document and proposal while listening is for communication and understanding presentation of a project work. Considering that the speaking is most needed in graduates work environment, it is suggested to give more time for speaking practice in English lesson, and give more material for writing project document. Hence, many essential topics which are not covered in the syllabus must be given time.

Keywords: The goal, a good quality of curriculum, English language skills, graduates work environment.
Kajian Eksperimental Live Bed Scour Di Hilir Bed Sill Pada Sedimen Dasar Tidak Seragam
Authors: Junaidi Junaidi , Mahmudi Wildana Latif , Suroso Suroso , Sugiharto Sugiharto
Published: November 2023

Proses gerusan terjadi pada kondisi clear water scour setelah tercapainya fase kesetimbangan (equilibrium) dimana dimensi lubang gerusan yang terjadi di hilir bangunan sangat bergantung pada waktu. Ada tiga tahap pembentukan lubang gerusan lokal, yaitu tahap awal yang cepat, tahap pembentukan, dan tahap akhir berupa perlambatan hingga mencapai kesetimbangan (equilibrium). Bentuk lubang gerusan sangat bergantung pada jarak antar bed sill. Ada dua bentuk lubang gerusan, yaitu bentuk quasi-parabolic dan spoon. Bentuk quasi-parabolic terjadi pada jarak yang pendek antar bed sill, sementara bentuk spoon terjadi pada jarak bed sill yang besar. Lapis armoring memiliki nilai diameter median (d50) yang makin besar dengan makin besarnya jarak interval antar bed sill. Fenomena gerusan di hilir bangunan hidraulik di alam terjadi pada kondisi banjir dimana juga terangkut material / butiran-butiran sedimen dari hulu. Penelitian ini dilakukan untuk mengamati perilaku gerusan di hilir bed sill pada kondisi adanya sedimen terangkut dari hulu bangunan (live bed scour) dengan material dasar saluran dari sedimen tidak seragam. Penelitian dilakukan di Laboratorium Hidraulika Jurusan Teknik Sipil Politeknik Negeri Semarang dengan menggunakan saluran terbuka / flume yang dilengkapi dengan sirkuit hidraulik, pintu, dan alat-alat ukur lainnya. Gerusan lokal di hilir bed sill pada kondisi live bed scour diteliti dengan melakukan serangkaian percobaan dimana material sedimen dasar tidak seragam digunakan dengan gradasi yang sama dengan sedimen yang disuplai dari hulu. Hasil penelitian menunjukkan bahwa kedalaman gerusan maksimum ys terbentuk secara cepat dan mencapai nilai mendekati kesetimbangan dalam waktu pendek (2 jam). Fase erosif jangka pendek secara jelas terbedakan dari fase jangka panjang berdasarkan profil pembentukan lubang gerusan terhadap waktu. Pada awal pengujian juga tampak bahwa kedalaman gerusan berkurang dengan meningkatnya debit aliran. Pengurangan kedalaman gerusan maksimum (ys) pada kondisi live bed scour dibanding pada kondisi clear water scour dapat diukur dari loncat morfologis a1. Nilai-nilai non dimensi rasio a1/Δ.D50 menegaskan bahwa persamaan yang digunakan dapat dipilih untuk a1/Δ.D50 hingga 9.0.

Kata kunci: Gerusan, bed sill, live bed scour, equilibrium, flume.
Keris Frameic Mbah Kerta
Authors: Ariyani Nurul Devi , Hendratno Eddy , Zuraedha Irmas , Hamida Nurul
Published: November 2023

Banyaknya limbah kertas khususnya limbah kertas fotocopy yang belum dimanfaatkan agar mempunyai nilai ekonomis tinggi merupakan peluang untuk membuka usaha baru khususnya dibidang souvenir yaitu frame. Keris Frameic Mbah Kerta (Kreasi Frame Unik Limbah Kertas Mengingat Momen Tanpa Batas) merupakan suatu inovasi dari mengolah limbah kertas yang biasanya hanya terbuang sia-sia yang diolah menjadi frame (pigura) unik untuk memenuhi keinginan pelanggan untuk menyimpan momen berharga. Tujuan dari program ini di antaranya adalah: 1) Memanfaatkan limbah kertas agar mempunyai nilai jual tinggi. 2) Menciptakan produk kerajinan tangan dari limbah kertas menjadi frame isian kreasi unik. 3) Mewadahi keinginan mahasiswa yang mempunyai jiwa wirausaha dan kreasi seni untuk membuka peluang usaha baru. Metode pembuatan frame yang digunakan meliputi 1) Pembuatan frame, dan 2) Pembuatan kreasi isian frame. Penjualan produk ini telah dilakukan selama bulan Juni hingga Agustus 2018, produk yang telah terjual sebanyak 55 unit, diperoleh omzet Rp 4.780.000, dengan keuntungan Rp 1.663.800, serta BEP Rp 3.320.000. Metode penjualan dan promosi dilakukan baik secara online yaitu melalui sosial media maupun secara offline yaitu direct selling dan konsinyasi. Berdasarkan hasil tersebut, maka usaha ini sangat menguntungkan dan dapat bermanfaat bagi lingkungan sekitar.
Rancang Bangun Mesin Sortir Ikan Berdasarkan Berat Dengan Mekanisme Pergerakan Konveyor
Authors: Pujono Pujono , Prasetia Indra Mega , Santoso Aldi Fadhlurohman
Published: November 2023

Sumber daya alam di darat maupun di laut merupakan sumber daya alam yang sangat berharga dan merupakan salah satu penunjang perekonomian di Indonesia. Salah satu sumber daya laut adalah bidang perikanan khususnya yang ada diwilayah Kabupaten Cilacap. Salah satu yang menentukan dalam pemasaran ikan yaitu keseragaman berat ikan, padahal para nelayan di wilayah kabupaten cilacap masih melakukan sortir berat ikan menggunakan cara manual. Kondisi seperti ini memberikan ide untuk merancang dan membuat sebuah alat atau mesin untuk membantu dalam hal penyortiran berat ikan supaya lebih cepat dibandingkan menggunakan metode manual, dan juga mudah dioperasikan oleh para nelayan. Proses perancangan yang dilakukan adalah dengan menggunakan pendekatan metode VDI 2222 yaitu melakukan tahap perencanaan, perancangan, pembuatan konsep dan penyelesaian/pembuatan produk. Proses produksi mesin sortir ikan berdasarkan berat ini dilakukan dengan beberapa proses yaitu pemotongan, CNC milling, bubut, las, perakitan dan finishing. Proses produksi tersebut bertujuan untuk mengetahui waktu proses produksi serta untuk dilakukan uji fungsi dan hasil pada mesin tesebut. Proses produksi mesin ini membutuhkan waktu proses CNC milling selama 11,06 jam; proses bubut selama 0,87 jam dan proses finishing selama 1,92 jam. Uji hasil menunjukkan bahwa kecepatan sortir ikan adalah 15 ikan/menit, dengan tingkat error penimbangan loadcell pada mesin sortir ikan dibandingkan dengan sortir timbangan manual adalah 0,68% dan tingkat kepresisian hasil timbang adalah 99,32%, maka secara umum dapat dikatakan bahwa mesin sortir ikan berdasarkan berat ikan berfungsi dengan baik
PENERAPAN IPTEKS LAS LITRIK DENGAN PENYAMBUNGAN LOGAM UNTUK KEBUTUHAN RUMAH TANGGA BAGI REMAJA PUTUS SEKOLAH DAN PEKERJA BANGUNAN
Authors: Ukiman Ukiman , Pawiro Dadiyono Amat , Nurhadi Imam , Suwarto Suwarto , Suroso Suroso , Yusetyowati Yusetyowati
Published: November 2023

Penduduk umr 18 tahun sampai dengan 24 tahun di kecamatan Rembang, Kabupaten Rembang kebanyakan  mata pencahariannya masih dalam ketidak pastian., misalnya  bekerja berpindah pindah di mana yang dapat menghasilkan. Mereka tidak mempunya profesi keahlian tertentu. Dengan kondisi tersebut, maka dapat diasumsikan  bahwa masih adnya pengangguran terutama pada remaja putus sekolah.. Banyak bermunculan usaha –usaha pengelasan ,tetapi yang menjadi permasalahan adalah pekerja las listrik  yang digunakan masih didatangkan dari luar Rembang. Sehingga hal ini kurang efektif dan tidak efisien untuk pengusaha, karena pengusaha  harus menyediakan tempat tinggal untuk pekerja. Dengan harapan pengusaha-pengusaha las listrik tidak kesulitan mecari pekerja , dan kelangkaan tenaga las listrik dapat teratasi dan dapat menekan biaya pengeluaran, serta dapat menyejahterakan masyarakat kalangan bawah yang ada didaerah Rembang dan sekitarnya maka tim pengabdiaan masyarakat Politeknik Negeri Semarang mengadakan kegiatan ini. Metode yang digunakan adalah pelatihan  yang meliputi  tentang teknik dasar las listrik serta pemotongan menjadi benda jadi sepeti teralis,pintu, daun jendela, rangka atap dan lain sebagainya.
FAKTOR-FAKTOR YANG MEMPENGARUHI MOTIVASI MAHASISWA DALAM PERKULIAHAN BERDASAR KINERJA DOSEN
Authors: Muslimah Muslimah , Trismanto Trismanto , Wiwoho Gurendi
Published: November 2023

Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi motivasi mahasiswa dalam mengikuti perkuliahan berdasarkan kinerja dosen dalam pembelajaran.Dalam penelitian ini pendekatan deskriptif kualitatif digunakan untuk menganalisis data.Populasi penelitiannya adalah mahasiswa FBB(Fakultas Bahasa dan Budaya) Universitas 17 Agustus 1945 Semarang yang diambil sampelnya secara purposive sample technique.Teknik pengumpulan data menggunakan angket dan wawancara. Hasil penelitian menunjukkan bahwa motivasi mahasisa FBB Universitas 17 Agustus 1945 Semarang cukup tinggi, begitu juga kinerja dosen dalam pembelajaran cukup tinggi. Adapun yang mempengaruhi motivasi mahasiswa dalam perkulihan antara lain cara dosen dalam menyampaikan materi perkuliahan sangat menarik, kedatangan dosen yang tepat waktu, pemberian feedback oleh dosen terhadap setiap tugas yang diberikan.
PENGEMBANGAN PRODUK OLAHAN BUAH MANGROVE JENIS API-API (AVICENNIA SPP) DI KELOMPOK PETANI MANGROVE LESTARI KELURAHAN MANGUNHARJO KECAMATAN TUGU, SEMARANG
Authors: Suhartono Edy , Santosa Stefanus , Yusetyowati Yusetyowati , Wibowo Hadi
Published: November 2023

Permanfaatan buah mangrove oleh Kelompok Petani Mangrove Lestari adalah mengolah bahan baku menjadi produk olahan. Metode yang digunakan dalam memecahkan masalah Kelompok Petani Mangrove Lestari yaitu dengan sosialisasi proses pengolahan tepung buah mangrove yang sesuai standar, menyediakan alat penggiling tepung untuk mendapatkan tepung yang berkualitas baik, dan demostrasi pengolahan tepung buah mangrove menjadi kue bolu dan sirup. Berdasarkan hasil sosialisasi pengabdian masyarakat di Kelurahan Mangunharjo Kecamatan Tugu,Semarang berhasil karena melihat antusiasme masyarakat Kelurahan tersebut yang mendapatkan ilmu terkait pengolahan tepung buah mangrove yang dapat meningkatkan pendapatan ekonomi msyarakat.
PENGARUH PEDAGANG KAKI LIMA DAN PARKIR TERHADAP KINERJA JALAN DI KOTA SEMARANG
Authors: Surya Buana Lalu Yahya , Abdilah Rifqi Aulia , Rabinah Aiun Hayatu , Risman Risman , Warsiti Warsiti
Published: November 2023

Aktifitas PKL dan kendaraan yang melakukan parkir pada badan jalan menimbulkan kemacetan lalu lintas dan berkurangnya tingkat pelayanan jalan. Tujuan dalam penelitian ini adalah mengidentifikasi dan menganalisis pengaruh keberadaan PKL dan parkir terhadap kinerja jalan. Metode penelitian yang digunakan adalah metode penelitian survey yang dilengkapi dengan observasi. Penelitian ini menggunakan data kuantitatif yang dianalisis dengan kualitatif deskriptif. Berdasarkan hasil penelitian, disimpulkan bahwa pada ruas jalan arteri, PKL dan parkir memiliki pengaruh yang signifikansebesar 0,026 terhadap DS dan 0,028 terhadap kecepatan, dengan kenaikan DS sebesar 14%, dan penurunan kecepatan sebesar 26%, hal tersebut juga terjadi karena pada lokasi penelitian terdapat U-Turn, lokasi tersebut merupakan jalan arteri 2 arah yang dipisah oleh median, serta perbedaan fungsi guna lahan. Sedangkan pada ruas jalan kolektor, keberadaan PKL dan parkir mempengaruhi DS sebesar 0,049 dengan kenaikan DS sebesar 7%. Sedangkan terhadap kecepatan pengaruhnya tidak signifikan sebesar 0,064, tapi terjadi penurunan kecepatan sebesar 7%. Pada ruas jalan lokal, keberadaan PKL dan parkir tidak berpengaruh signifikan baik terhadap DS maupun kecepatan, namun terjadi peningkatan DS sebesar 80%, dan penurunan kecepatan sebesar 10%,selain PKL dan parkir, hal tersebut juga disebabkan oleh volume lalu lintas yang secara langsung mempengaruhi hambatan dan kinerja jalan
СЕК’ЮРЕТИЗАЦІЯ АКТИВІВ ЯК ЕЛЕМЕНТ ЕФЕКТИВНОСТІ УПРАВЛІННЯ ПОРТФЕЛЕМ СТРАХОВОЇ КОМПАНІЇ
Authors: Халатур Світлана , Ільченко Олександр
Published: November 2023

У статті розкриваються принципи сек’юретизації , а також проблема нестачі фінансових ресурсів на сучасному фінансовому ринку в контексті управління портфелем страхової компанії. Виділено переваги сек’юретизації та функціональні особливості інвестиційних учасників і суб’єктів фінансового ринку, які задіяні в процесі сек’юретизації. Узагальнено підходи до визначення класифікаційних ознак за окремими видами активів при їх сек’юретизації. Авторами визначено напрямки вдосконалення механізму процесу залучення грошових коштів і фінансових ресурсів для фінансування страховиків. Також запропоновано способи залучення капіталу з метою інвестування активів страхових компаній у високодохідні інструменти. Проаналізовано диференціацію грошових потоків при підвищенні ефективності інвестування окремих фінансових інструментів страхової організації.
THE RELATIONSHIP BETWEEN SAFETY CLIMATE WITH OCCUPATIONAL SAFETY AND HEALTH (OSH) IN EMPLOYEES OF THE MINE DEPARTMENT AND RAW MATERIAL MANAGEMENT OF PT. XYZ
Authors: Wahyuni Indah , Amir Arni , Rahayuningsih Tri , Armalita Rani , Pratama Weno
Published: November 2023

This study aims to see the relationship between safety climate and occupational safety and health (OSH) for employees of the Mining and Raw Materials Management Department of PT. XYZ. The research method used in this study is a quantitative method with Spearman's Rho analysis technique. Participants in this study consisted of 100 employees of the Mining and Raw Materials Management Department of PT. XYZ was obtained using the accidental sampling technique. Data collection was carried out using the 24-item Nordic Occupational Safety Climate Questionnaire (NOSACQ-24) and the Workplace Health and Safety Instrument German (WHASI-G). The reliability on the NOSACQ-24 measuring instrument is .905 and on the WHASI-G measuring instrument is .911. The results of this study indicate that there is a significant positive relationship between safety climate and occupational safety and health (OSH). This can be seen from the significance obtained by .000 (p<.05) and the correlation coefficient value of .699.
Analisis Penurunan Angka Air Tidak Berekening (Non Revenue Water) Unit Kecamatan Kalianget Kabupaten Sumenep
Authors: Rezky Widianto Dwi , Hadi Wahyono
Published: November 2023

Konsumsi air bersih di Kabupaten Sumenep dilaksanakan oleh Perumdam Sumekar Kabupaten Sumenep yang merupakan Badan Usaha Milik Daerah. Berdasarkan laporan Audit BPKP Tahun 2021, angka Air Tidak Berekening mencapai 33,32%. Penelitian ini bertujuan untuk menghitung besaran kehilangan air dan strategi yang digunakan dalam rangka menurunkan angka kehilangan air menggunakan perhitungan Neraca Air dan ILI (Infrastructure Leakge Index). Perhitungan Neraca Air bertujuan mengidentifikasi kehilangan air yang terjadi dalam sistem pendistribusian. ILI (Infrastructure Leakge Index) bertujuan untuk mempertimbangkan pengelolalaan jaringan dengan menggunakan skala. Hasil penelitian menggunakan metode Neraca Air, Perumda Air Minum Sumekar Kabupaten Sumenep mengalami kebocoran sebesar 31,3 % setara dengan 284.979 m3/tahun. Dengan kerugian financial sebesar Rp. 986.962.752 -/tahun. Sedangkan dengan metode ILI, Perumda Air Minum Sumekar Kabupaten Sumenep masuk pada golongan B dengan nilai kebocoran 100-200 liter/sambungan/hari, sehingga Perumdam Sumekar Kabupaten Sumenep tidak memanfaatkan hasil produksi air secara efisien dan perlu dilakukan upaya penanganan penurunan angka kehilangan air
Triangle Manajemen Callus: Zinc Cream, Hydrocoloid dan Polyurethane Foam Pada Pasien Diabetic Neuropathy
Authors: Bahri Khairul , Hidayat Rizki
Published: November 2023

ABSTRAK Diabetes neuropati adalah kondisi yang disebabkan oleh diabetes yang merusak berbagai bagian sistem saraf. Ini terjadi karena kadar gula dalam darah tinggi yang dapat merusak saraf secara bertahap. Hilang sensasi pada kaki karena neuropati diabetik dapat menyebabkan kapalan akibat tekanan atau gesekan pada kaki. Callus terbentuk di area tubuh yang mengalami gesekan atau tekanan yang berlebihan pada telapak kaki, tumit, atau jari-jari. Gesekan dan tekanan berulang pada kaki adalah beberapa penyebab callus. Salah satu metode pengobatan dan pencegahan callus adalah offloading, yang mengurangi tekanan pada kaki dan mencegah terbentuknya kepalan. Tujuan dari studi kasus ini melihat efektivitas penggunaan zinc cream, hidrokoloid dan polyurethane foam dalam manajemen callus pada pasien dengan diabetic neuropathy. WINNER score sebagai evaluasi penyembuhan luka. Kesimpulan didapatkan dengan hasil Penggunaan zinc cream sebagai balutan primer, hydrocolloid sebagai pelindung sekitar luka dan polyurethane foam sebagai balutan sekunder dan off-loading efektif dalam manajemen callus pada diabetes neuropati. Kata Kunci: Diabetic Neuropati, Callus, Wound Care  ABSTRACT Diabetic neuropathy is a condition caused by diabetes that damages different parts of the nervous system. This occurs due to high blood sugar levels that gradually damage the nerves. Loss of sensation in the feet due to diabetic neuropathy can lead to the formation of calluses due to pressure or friction on the feet. Calluses form in areas of the body that experience excessive friction or pressure, such as the soles of the feet, heels, or fingers. Friction and repeated pressure on the foot are some of the causes of calluses. Off-loading is one of the methods used to treat and prevent calluses, which reduces pressure on the legs and prevents calluses from forming. The purpose of this case study was to evaluate the effectiveness of using zinc cream, hydrocolloids, and polyurethane foam in managing calluses in patients with diabetic neuropathy. The WINNER score was used to evaluate wound healing. The results showed that the use of zinc cream as a primary dressing, hydrocolloid as a protector around the wound, polyurethane foam as a secondary dressing, and off-loading was effective in managing calluses in diabetic neuropathy. Keyword: Diabetic Neuropathy, Callus, Wound Care
Efektivitas Media Vidio dan Flipchart Terhadap Tingkat Pengetahuan Siswa Tentang Kesehatan Reproduksi Remaja di Smp Tahta Syajar
Authors: Raihana Ananda Alvi , Futriani Elfira Sri
Published: November 2023

ABSTRACT The 2015 Global School Health Survey (GSHS) report shows that 3.3% of adolescents aged 15-19 years suffer from AIDS; only 9.9% of women and 10.6% of men aged 15-19 have in-depth knowledge about HIV/AIDS; and 0.7% of women and 4.5% of men had premarital sex. So this raises problems identified in adolescent risk behavior and reproductive health problems. This research was conducted to determine the effectiveness of video media and flipcharts on the level of students' knowledge about adolescent reproductive health at Tahta Syajar Middle School. This research was a quasy experimental study using a pre-post test control group design, namely the research was carried out by making the first observation (pre test) before the intervention was carried out, then a second observation (post test) was carried out after the intervention was carried out. The number of respondents in this study were 36 respondents. There is a difference between the level of knowledge of students and other students, namely by increasing knowledge about reproductive health by providing education through video media and flipcharts. Keywords: Adolescent Reproductive Health, Flipchart, Video ABSTRAK Laporan Global School Health Survey (GSHS) tahun 2015 menunjukkan 3,3% dari remaja usia 15-19 tahun menderita AIDS; hanya 9,9% perempuan dan 10,6% lakilaki berusia 15-19 tahun yang memiliki pengetahuan mendalam tentang HIV/AIDS; dan sebesar 0,7% perempuan dan 4,5% laki-laki telah melakukan hubungan seks pranikah. Sehingga hal ini menimbulkan masalah yang teridentifikasi pada perilaku berisiko remaja dan masalah kesehatan reproduksi. Penelitian ini dilakukan untuk mengetahui Efektivitas media video dan flipchart terhadap tingkat pengetahuan siswa tentang Kesehatan reproduksi remaja di SMP Tahta Syajar. penelitian ini adalah quasy eksperimental dengan menggunakan rancangan control group pre-post test yaitu penelitian dilaksanakan dengan melakukan observasi pertama (pre test) sebelum dilakukan intervensi selanjutnya dilakukan observasi kedua (post test) pada saat setelah dilakukan intervensi. Jumlah responden dalam penelitian ini 36 responden. Ada perbedaan antara tingkat pengetahuan siswa dengan siswa yang lain yaitu dengan meningkatkan pengetahuan tentang Kesehatan reproduksi dengan memberi edukasi melalui media video dan flipchart. Kata Kunci: Kesehatan Reproduksi Remaja, Flipchart, Video
Analysis of The Benefits of Financial Technology and Financial Socialization Towards Financial Behavior in Students in Surabaya Post Pandemic with Financial Literacy as The Intervening Variable
Authors: Radianto Wirawan Dwi , Suryanto Angelina
Published: November 2023

The purpose of this study is to investigate financial behavior among university students in Surabaya and analyze the relationship between perceived usefulness of financial technology, financial socialization, and financial literacy as an intervening variable. Conclusive causality research is used for this research with primary data collected from questionnaires. The sampling techniques used a combination of proportional stratified random sampling and purposive sampling towards 466 university students from 6 universities in Surabaya. Data analyzed using Partial Least Squares - Structural Equation Model (PLS-SEM) techniques. The result shows that financial literacy and financial socialization positively impacts financial behavior while perceived usefulness of financial technology variables does not affect financial behavior. Mediation results showsthat financial literacy is able to mediate perceived usefulness of financial technology and financial socialization towards financial behavior of university students in Surabaya. Through this research is expected to be the reference for various parties, especially for curriculum makers to consider optimization technical teaching strategies and assessment indicators in basic financial outreach.
Lung cancer diagnosis and mortality beyond 15 years since quit in individuals with a 20+ pack‐year history: A systematic review
Authors: Kondo Karli K. , Rahman Basmah , Ayers Chelsea K. , Relevo Rose , Griffin Jessica C. , Halpern Michael T.
Published: November 2023

Current US lung cancer screening recommendations limit eligibility to adults with a pack‐year (PY) history of ≥20 years and the first 15 years since quit (YSQ). The authors conducted a systematic review to better understand lung cancer incidence, risk and mortality among otherwise eligible individuals in this population beyond 15 YSQ. The PubMed and Scopus databases were searched through February 14, 2023, and relevant articles were searched by hand. Included studies examined the relationship between adults with both a ≥20‐PY history and ≥15 YSQ and lung cancer diagnosis, mortality, and screening ineligibility. One investigator abstracted data and a second confirmed. Two investigators independently assessed study quality and certainty of evidence (COE) and resolved discordance through consensus. From 2636 titles, 22 studies in 26 articles were included. Three studies provided low COE of elevated lung cancer incidence beyond 15 YSQ, as compared with people who never smoked, and six studies provided moderate COE that the risk of a lung cancer diagnosis after 15 YSQ declines gradually, but with no clinically significant difference just before and after 15 YSQ. Studies examining lung cancer‐related disparities suggest that outcomes after 15 YSQ were similar between African American/Black and White participants; increasing YSQ would expand eligibility for African American/Black individuals, but for a significantly larger proportion of White individuals. The authors observed that the risk of lung cancer not only persists beyond 15 YSQ but that, compared with individuals who never smoked, the risk may remain significantly elevated for 2 or 3 decades. Future research of nationally representative samples with consistent reporting across studies is needed, as are better data from which to examine the effects on health disparities across different populations.
Pengembangan Lembar Kerja Peserta Didik (LKPD) Berbasis Nilai-Nilai Karakter Dasa Darma Pramuka pada Pembelajaran PPKn Kelas V SDN 72 Bengkulu Tengah
Authors: Hendriwati Hendriwati , Djuwita Puspa , Hambali Daimun
Published: November 2023

Abstract This research is motivated by a decrease in the character values of students and the absence of a LKPD that contains the character values of Dasa Darma Pramuka at SDN 72 Bengkulu Tengah. This affects the achievement of learning objectives, namely forming students with character. This study aims to determine the validity and practicality of LKPD based on the values of Dasa Darma Pramuka. This research is a development research using the 4- D model which consists of four stages, namely define, design, develop and disseminate. This research was only conducted until the develop stage, namely the validity test and practicality test. The instrument used was a validity test questionnaire and a practicality test questionnaire. The validity test was carried out by 6 validators, namely 2 material experts, 2 linguists and 2 graphic experts. The practicality test was carried out on 19 students of SDN 72 Bengkulu Tengah. Data from the validity and practicality test results were analyzed by using percentage techniques and processed descriptively. The results of the LKPD validity test based on the values of Dasa Darma by the validator in terms of aspects of the front page, table of contents, study instructions, material feasibility, language presentation, and graphic feasibility, material eligibility was obtained 0.81 with proper criteria, language eligibility results 0, 75 with very feasible criteria and a graphical feasibility result of 0.81. The practicality test results of the LKPD based on the values of the Dasa Darma Pramuka, obtained a value of 80.69 by the teacher and 80.95 by students with practical criteria. Based on the results of the study it can be concluded that the use of LKPD values of Dasa Darma Pramuka SDN 72 Bengkulu Tengah in grade V is very feasible and very practical.Keywords        : Dasa Darma, Character, student worksheet
Myofibrillar Creatine Kinase Activity Inferred from a 3D Model
Authors: Mejsnar JA , Sopko B , Gregor M
Published: November 2023

Myofibrillar creatine kinase (CK) that buffers ATP during fluctuating muscle energy metabolism has been selected for studies of conformational changes underlying the cellular control of enzyme activity. The force field was computed for three energetic states, namely for the substrate-free CK molecule, for the molecule conjugated with the MgATP complex, and for the molecule conjugated with the pair of reactants MgATP-creatine. Without its substrates, the enzyme molecule assumes an inactive "open" form. Upon binding of the MgATP complex, the CK molecule takes up a reactive "closed" conformation. Subsequent binding of creatine yields a nonreactive "intermediary" conformation. Acid-base catalysis is considered to be the basic principle for the reversible transfer of the phosphoryl group between the substrates. The results indicate that the substrate-induced energy minimizing conformational changes do not represent a sufficient condition for CK activity and that some other essential component of physiological control at the cellular level is involved in the transition from the intermediary to the closed structure of the molecule.
Methodologies of the Validation of Software Architectures
Authors: El Murabet Amina , Abtoy Anouar
Published: November 2023

Software architecture validation is the process of assessing whether a software architecture meets its intended requirements and goals. It is an important step in the software development process, as it can help to identify and address potential problems early on before they become more costly and difficult to fix. There are a variety of different methodologies that can be used to validate software architecture. Some of the most common methodologies include Architectural evaluation methods, Architecture tests and reviews, and Model-based validation. This paper will provide an overview of the different methodologies that can be used to validate software architecture. Apart from that, it also analyzes and summarizes the strengths and weaknesses of each method so that it can guide determining the most appropriate methodology for a particular case.
Poems
Authors: Czech Natalie
Published: November 2023

Natalie Czech's work has explored interfaces between conceptual photography, poetry and everyday objects. In ‘poems’, presented in this issue of CounterText and extracted from a forthcoming work, she presents a lexicon of common computer icons that visually refer to familiar objects while indicating different functionality within computing. The work plays also with semantic slippage and with permutational potential within the captioning provided.
Pengaruh Efek Kontaminasi Isolator KeramikTerhadap Rugi DayaSaluran Udara Tegangan Tinggi
Authors: Ruwah Joto  , Dhesah Kharisma Dhimas , Tresna Umar Syamsuri  , Aly Imron
Published: November 2023

In meeting consumers' needs for electric power continuously, the reliability of electric power distribution is something that needs to be considered. One of the reliability parameters is the network's ability to distribute power from generators continuously, with the allowable voltage and frequency quality. For this reason, the presence of an insulator in the power distribution system is very important considering its function is to separate live conductors from their supports. If the isolation properties do not function, a voltage failure will occur so that power distribution will stop, resulting in low system reliability. From the data from the calculation results of 150 kV high voltage overhead line power losses due to flashovers on insulators installed in each fouling area, it is clear that increasing the contaminant value will make it easier for flashovers to occur which cause very large power losses and conversely, insulators that are clean make it difficult. the occurrence of flashover so as to reduce power losses on the transmission line. The appropriate insulator to use is the fog type, because the diameter is wider, increasing the propagation distance so that the insulator's ability to withstand greater voltage
The Dynamics of Evangelism in a Multicultural Context: Challenges and Opportunities for Contextualization
Authors: Soegianto Soegianto , Abigail Lolong Prinsipessia Putri
Published: November 2023

Evangelism in a multicultural context has become a primary concern in the mission of the modern church. In an effort to comprehend the dynamics involved in evangelism within multicultural environments, this research aims to identify the primary challenges faced by evangelists while also detailing the emerging opportunities in the endeavor to contextualize the message of the Gospel. Through an in-depth literature review in qualitative research, this study reveals the complexity of the multicultural context within the scope of evangelism. The main challenges encompass differences in religious beliefs, language disparities, and cultural tensions, all of which necessitate a prudent and adaptable approach. However, within these challenges, significant opportunities also arise. These opportunities include the formation of intercultural bridges, an improved understanding of religious pluralism, and the potential for collaboration among people of different faiths. The research findings emphasize the importance of contextualizing the Gospel message to establish an effective and meaningful approach within a multicultural context. This study provides valuable insights for churches and evangelists operating in multicultural environments, stimulating discussions about the role of contextualization in disseminating the message of the Gospel in an increasingly diverse society.
INO80 function is required for mouse mammary gland development, but mutation alone may be insufficient for breast cancer
Authors: Thang Nguyen Xuan , Han Dong Wook , Park Chanhyeok , Lee Hyeonji , La Hyeonwoo , Yoo Seonho , Lee Heeji , Uhm Sang Jun , Song Hyuk , Do Jeong Tae , Park Kyoung Sik , Choi Youngsok , Hong Kwonho
Published: November 2023

The aberrant function of ATP-dependent chromatin remodeler INO80 has been implicated in multiple types of cancers by altering chromatin architecture and gene expression; however, the underlying mechanism of the functional involvement of INO80 mutation in cancer etiology, especially in breast cancer, remains unclear. In the present study, we have performed a weighted gene co-expression network analysis (WCGNA) to investigate links between INO80 expression and breast cancer sub-classification and progression. Our analysis revealed that INO80 repression is associated with differential responsiveness of estrogen receptors (ERs) depending upon breast cancer subtype, ER networks, and increased risk of breast carcinogenesis. To determine whether INO80 loss induces breast tumors, a conditional INO80-knockout (INO80 cKO) mouse model was generated using the Cre-loxP system. Phenotypic characterization revealed that INO80 cKO led to reduced branching and length of the mammary ducts at all stages. However, the INO80 cKO mouse model had unaltered lumen morphology and failed to spontaneously induce tumorigenesis in mammary gland tissue. Therefore, our study suggests that the aberrant function of INO80 is potentially associated with breast cancer by modulating gene expression. INO80 mutation alone is insufficient for breast tumorigenesis.
Postoperative acute kidney injury after on-pump cardiac surgery in patients with connective tissue disease
Authors: Zhang Xue , Miao Qi , Yu Chunhua , Zhang Yuelun , Wu Di , Tian Yajie , Li Hanchen , Wang Chunrong
Published: November 2023

Objective

Patients with connective tissue disease have a poor prognosis after receiving cardiac surgery. This study described the clinical scenarios and investigated factors correlated with acute kidney injury (AKI) after on-pump cardiac surgery in patients with systemic lupus erythematosus (SLE) or vasculitis.

Methods

Patients with SLE or vasculitis who underwent on-pump cardiac surgery from March 2002 to March 2022 were enrolled, while patients with preoperative renal dysfunction were excluded. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Uni- and multivariable analyses were performed to identify potential factors associated with postoperative AKI.

Results

Among 123 patients enrolled, 39 (31.7%) developed AKI within seven days after receiving on-pump cardiac surgery. Four patients died in the hospital, resulting in an overall in-hospital mortality of 3.3%, and all deaths occurred in the AKI group. Patients in the AKI group also had longer ICU stays (median difference 3.0 day, 95% CI: 1.0–4.0, P < 0.001) and extubation time (median difference 1.0 days, 95% CI: 0–2.0, P < 0.001) than those in the non-AKI group. Multivariable logistic regression revealed that BMI over 24 kg/m2 (OR: 3.00, 95% CI: 1.24–7.28) and comorbid SLE (OR: 4.73, 95% CI: 1.73–12.93) were independently correlated with postoperative AKI.

Conclusion

Factors potentially correlated with AKI following on-pump cardiac surgery in patients with connective tissue disease were explored. Clinicians should pay more attention to preoperative evaluation and intraoperative management in patients with risk factors.
T-helper cells flexibility: the possibility of reprogramming T cells fate
Authors: Khantakova Julia N. , Sennikov Sergey V.
Published: November 2023

Various disciplines cooperate to find novel approaches to cure impaired body functions by repairing, replacing, or regenerating cells, tissues, or organs. The possibility that a stable differentiated cell can reprogram itself opens the door to new therapeutic strategies against a multitude of diseases caused by the loss or dysfunction of essential, irreparable, and specific cells. One approach to cell therapy is to induce reprogramming of adult cells into other functionally active cells. Understanding the factors that cause or contribute to T cell plasticity is not only of clinical importance but also expands the knowledge of the factors that induce cells to differentiate and improves the understanding of normal developmental biology. The present review focuses on the advances in the conversion of peripheral CD4+ T cells, the conditions of their reprogramming, and the methods proposed to control such cell differentiation.
Unveiling the novel immune and molecular signatures of ovarian cancer: insights and innovations from single-cell sequencing
Authors: Li Zhongkang , Gu Haihan , Xu Xiaotong , Tian Yanpeng , Huang Xianghua , Du Yanfang
Published: November 2023

Ovarian cancer is a highly heterogeneous and lethal malignancy with limited treatment options. Over the past decade, single-cell sequencing has emerged as an advanced biological technology capable of decoding the landscape of ovarian cancer at the single-cell resolution. It operates at the level of genes, transcriptomes, proteins, epigenomes, and metabolisms, providing detailed information that is distinct from bulk sequencing methods, which only offer average data for specific lesions. Single-cell sequencing technology provides detailed insights into the immune and molecular mechanisms underlying tumor occurrence, development, drug resistance, and immune escape. These insights can guide the development of innovative diagnostic markers, therapeutic strategies, and prognostic indicators. Overall, this review provides a comprehensive summary of the diverse applications of single-cell sequencing in ovarian cancer. It encompasses the identification and characterization of novel cell subpopulations, the elucidation of tumor heterogeneity, the investigation of the tumor microenvironment, the analysis of mechanisms underlying metastasis, and the integration of innovative approaches such as organoid models and multi-omics analysis.
Trophic ecophysiology of the native green shore crab, Carcinus maenas, and the invasive Asian shore crab, Hemigrapsus sanguineus, in the rocky intertidal of Helgoland (North Sea)
Authors: Saborowski Reinhard , Bartolin Patrick , Koch Marie , Jungblut Simon
Published: November 2023

The brachyuran crabs Carcinus maenas and Hemigrapsus sanguineus belong to the most ´successful´ invaders along the oceans coasts. In 2009, H. sanguineus appeared at the rocky intertidal of the island of Helgoland in the North Sea, where it encounters the native Green shore crab, C. maenas. H. sanguineus established a self-sustaining population, approaching in numbers and biomass that of C. maenas. Both species are considered to be opportunistic omnivores with variable food preferences and, thus, are potential competitors for food. To evaluate the intrinsic properties of either species to utilize food, we analyzed their stomach content, the morphology of the gastric mills, which shred the ingested food, the activities of digestive enzymes during a seasonal cycle, and the stable isotope ratios. A huge share of the stomach contents was macerated and, thus, could not be identified. The shares of animal food and algae food were almost equal in C. maenas but algae food dominated over animal food in H. sanguineus. The gastric mill of C. maenas shows blunt medial tooth and rounded lateral teeth, which indicates efficient grinding of a carnivorous diet. In contrast, the gastric mill of H. sanguineus shows sharp ridges, which facilitate cutting of algal food. The activities of the proteolytic enzymes trypsin and leucine-aminopeptidase were almost equal in both species with slightly higher activities in C. maenas in summer. The activities of the carbohydrases laminarinase and amylase dominated in H. sanguineus during all seasons. Stable isotope ratios indicate a higher degree of carnivory in C. maenas. The morphological and biochemical features indicate that C. maenas is better suited to utilize animal food and H. sanguineus algal food. Upon scarcity of animal food or severe competition with C. maenas, H. sanguineus may be able to increase the amount of algal food and to utilize it efficiently.
Candidate composite biomarker to inform drug treatments for diabetic kidney disease
Authors: Jones Roger D. , Abebe Seyum , Distefano Veronica , Mayer Gert , Poli Irene , Silvestri Claudio , Slanzi Debora
Published: November 2023

Introduction

Current guidelines recommend renin angiotensin system inhibitors (RASi) as key components of treatment of diabetic kidney disease (DKD). Additional options include sodium-glucose cotransporter-2 inhibitors (SGLT2i), glucagon-like peptide 1 receptor agonists (GLP1a), and mineralocorticoid receptor antagonists (MCRa). The identification of the optimum drug combination for an individual is difficult because of the inter-, and longitudinal intra-individual heterogeneity of response to therapy.

Results

Using data from a large observational study (PROVALID), we identified a set of parameters that can be combined into a meaningful composite biomarker that appears to be able to identify which of the various treatment options is clinically beneficial for an individual. It uses machine-earning techniques to estimate under what conditions a treatment of RASi plus an additional treatment is different from the treatment with RASi alone. The measure of difference is the annual percent change (ΔeGFR) in the estimated glomerular filtration rate (ΔeGFR). The 1eGFR is estimated for both the RASi-alone treatment and the add-on treatment.

Discussion

Higher estimated increase of eGFR for add-on patients compared with RASi-alone patients indicates that prognosis may be improved with the add-on treatment. The personalized biomarker value thus identifies which patients may benefit from the additional treatment.
Complete genome sequencing and comparative genomic analysis of three donkey Streptococcus equi subsp. equi isolates
Authors: Zhang Yuwei , Lv FenFen , Su Yan , Zhang Huan , Zhang Baojiang
Published: November 2023

Introduction

Streptococcus equi subspecies equi (S. equi) is the causative agent of strangles, which is one of the most common and highly contagious respiratory infectious illnesses in horses. Streptococcus equi (S. equi) is a horse-specific pathogen that originated from the closely related zoonotic pathogen Streptococcus equi subspecies zooepidemicus (S. zooepidemicus). Despite decades of research, the movement of genetic material across host-restricted diseases remains a mystery.

Methods

Three S. equi donkey isolates (HTP133, HTP232, and HT1112) were recently isolated from a strangles epidemic on donkey farms in China’s Xinjiang Province. In this study, we performed a comprehensive comparative analysis of these isolates using whole genome sequencing and compared them to the published genomic sequences of equine strain S. equi 4047 to uncover evidence of genetic events that shaped the evolution of these donkey S. equi isolates’ genomes.

Results

Whole genome sequencing indicated that both strains were closely related, with comparable gene compositions and a high rate of shared core genomes (1788-2004). Our comparative genomic study indicated that the genome structure is substantially conserved across three donkey strains; however, there are several rearrangements and inversions when compared to the horse isolate S. equi 4047. The virulence factors conveyed by genomic islands and prophages, in particular, played a key role in shaping the pathogenic capacity and genetic diversity of these S. equi strains. Furthermore, we discovered that the HT133 isolate had a strong colonization ability and increased motility; the HT1112 isolates had a significantly higher ability for antimicrobial resistance and biofilm formation, and the HT232 isolate gained pathogenic specialization by acquiring a bacteriophage encoding hyaluronate lyase.

Discussion

In summary, our findings show that genetic exchange across S. equi strains influences the development of the donkey S. equi genome, offering important genetic insights for future epidemiological studies of S. equi infection.