bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Endurance Training on Fibronectin Gene Expression of the Sciatic Nerve in Diabetic Rats
Authors: Jalilian Hamed Nahid , Gharakhanlou Reza , Peeri Maghsoud
Published: July 2020

- Diabetic neuropathy can cause disorders in axon transmission, changes in the extracellular matrix, and peripheral nerve damages. However, its mechanism, along with the beneficial effects of exercise on these disorders is not entirely clear. The aim of the current study was to assess changes in fibronectin mRNA gene expression level of the sciatic nerve in rats with streptozotocin-induced diabetes after endurance training. Eighteen male Wistar rats (10 weeks old with 250±20 gr weight) were randomly assigned to three groups, including healthy, induced diabetes and induced diabetes plus endurance training. Induction of diabetes was conducted using an intraperitoneal injection of a single dose of streptozotocin (STZ). Neuropathy was confirmed using the behavioral tests. Rats in induced diabetes plus training group had 8 weeks of moderate and increasing intensity endurance training on the treadmill. The Fibronectin mRNA gene expression level of the sciatic nerve was assessed using Real-time-PCR. Changes in fibronectin protein and myelin thickness were measured by immunohistochemistry and luxol fast blue staining. The mean and standard deviation was used to report descriptive data. Data were entered into SPSS 22. Fibronectin mRNA gene expression level (1.90) of sciatic nerve fibronectin protein and myelin thickness reduced significantly due to diabetes (P<0.05). Eight weeks of endurance training increased fibronectin gene expression of sciatic nerve fibronectin protein and prevented further destruction of myelin, which was statistically significant. The results showed that diabetes leads to changes in the extracellular matrix and the reduction of the sciatic nerve myelin thickness. Endurance training as a non-drug strategy is effective in preventing these damages.
Clinico-Laboratory Profile of Dengue Patients at Sir T. Hospital, Bhavnagar, India
Authors: Patel Nilesh D. , Desai Kairavi J. , Sarvaiya Jatin , Malek Saqlain
Published: July 2020

Dengue fever is caused by any one of four types of dengue viruses (DEN1-DEN4), spread mainly by Aedes aegypti. India had the largest number of dengue cases, with about 33 million apparent and another 100 million asymptomatic infections occurring annually. The patients typically present with the sudden onset of fever, frontal headache, retroorbital pain. The laboratory diagnosis can be made by IgM ELISA or by NS1 antigen-detection ELISA during the acute phase. This research was conducted from January 2018 to December 2018 at Sir T. hospital and Government Medical College in Bhavnagar, Gujarat. The patients having complaints of fever, headache, myalgia, arthralgia or rash, were clinically examined, and laboratory investigated for dengue with NS1 and/or IgM dengue antibody. A total of 536 patients was screened, of which 112 patients were diagnosed as dengue fever at 21% dengue positivity rate, based on detection of NS1 (46/304, 15%), and antidengue IgM (66/232, 28%) in their sera. The majority of the patients were males (77/112, 69%). The majority of patients were in 11–30 years’ age group (66/316, 21%). Fever (100%) was the chief presenting complaint, followed by headache (83, 93%), and myalgia (79, 89%). The highest number (28) of dengue patients was observed in the month of October 2018. According to this study results, the physicians in the dengue-endemic area should be aware of dengue in acute febrile illnesses and use the appropriate laboratory tests such as NS1 antigen and IgM antibodies for early dengue diagnosis. This can help clinicians to prevent morbidity and mortality associated with dengue.
Poland Syndrome With Renal Stone: A Case Report
Authors: Kafi Naimeh , Bakhshaei Sina , Mousavi Maryam , Shafiepour Mohsen
Published: July 2020

Poland syndrome is a rare congenital anomaly with various presentations. The most consistent findings of this syndrome are hypoplasia or aplasia of the sternocostal part of the pectoralis major muscle and upper limb malformations. Here, we are reporting a case of Poland syndrome with renal stone, a new finding that has not been reported in previous literature.
Serum Cystatin C as a Potential Marker for Glomerular Filtration Rate in Patients with Cholangiocarcinoma
Authors: Ciin Mang Ngaih , Proungvitaya Tanakorn , Proungvitaya Tanakorn , Limpaiboon Temduang , Roytrakul Sittiruk , Cha’on Ubon , Tummanatsakun Doungdean , Proungvitaya Siriporn
Published: July 2020

Background: Cholangiocarcinoma (CCA) is the second most common primary hepatobiliary cancer. These patients have meager prognosis and short-term survival. Precise assessment of glomerular filtration rate is a fundamental aspect of clinical care in cancer patients. Cystatin C has been proposed to be superior to creatinine, a well-known marker of renal function. This study aimed to evaluate cystatin C as a marker of GFR calculation in CCA patients.
Materials and Methods: One hundred thirty serum samples from CCA patients and 32 from controls were included in this study. Serum cystatin C was measured using immunoturbidity assay. Estimated glomerular filtration rate was calculated by three equations established by chronic kidney disease epidemiology collaboration (based on creatinine and/or cystatin C).
Results: Serum cystatin C in CCA patients was higher than that of controls (p=0.0002). Cystatin C was positively correlated with BUN in CCA group (p=0.019). eGFR based on cystatin C and based on both cystatin C and creatinine in CCA was low with significantly different from those of control (p<0.001). Although there was no difference in eGFR using three equations in control, creatinine based eGFR was high with significantly different from eGFR based on cystatin C and on both creatinine and cystatin C in CCA (P=0.000). Proportion in each eGFR stage by three equations showed a high sensitivity with significantly different in CCA (p<0.05).
Conclusion: There was a high sensitivity of cys C with significant difference between creatinine and/or cystatin C based eGFR in CCA patients. It should be taken into consideration of mild changes in eGFR by cystatin C which is important in managing drug dosage for CCA patients.
Relationship between the Expression of the Thymidylate Synthase and the Prognosis of Gastric Cancer Patients Treated with Combinational Chemotherapy Regimen Including Fluorouracil, Docetaxel and Cisplatin
Authors: Aznab Mozaffar , Ahmadi Seyed Majid , Khazaei Sedigheh , Khazaei Sedigheh , Ahmadi Seyed Mojtaba , Khazaei Mansour , Hamdi Hamid
Published: July 2020

Background: Thymidylate synthase is one of the target enzymes of 5-fluorouracil. However, the clinical and prognostic significance of TS expression in gastric cancer has remained controversial. In this study, the expression of thymidylate synthase was evaluated in gastric cancer patients treated with combinational chemotherapy; moreover, the association between TS expression and clinicopathologic characteristics and overall survival of the patients were also assessed.
Materials and Methods: In this descriptive study, 89 pathological samples were gathered from patients at Kermanshah hospitals during 2008-2017. The survival status of patients was recorded and their overall survival was evaluated individually.
Results: The average survival period for low and high thymidylate synthase groups was 54 and 50 months, respectively, meaning higher survival time in the lower thymidylate group. But this difference was not statistically significant (log Rank=0.88). In addition, sex, stage, recurrence, and survival had no significant difference between the low and high expression of thymidylate synthase groups (p=0.89).
Conclusion: The results clearly indicated that the level of thymidylate synthase is not a significant modulator of 5- fluorouracil in gastric cancer patients. Nevertheless, evaluation of the level of the enzymes and markers as well as their effects are highly recommended for accurate selection of chemotherapeutical strategies.
Body Mass Index, Age, Weight, and Psychosocial Status Effect on Bone Mineral Density in Postmenopausal Women on Hemodialysis
Authors: Hosseininejad Seyyed-Mohsen , Aghaei Mehrdad , Mohebi Hossein , Roshandel Gholamreza , Tabatabaei Sahab-Sadat , Amirkhanlou Saeid
Published: July 2020

Background: Decreased bone mass, often measured using bone mineral density (BMD) is frequently seen in patients with end-stage renal disease (ESRD) undergoing hemodialysis. It may cause serious bone health problems such as fractures. Several risk factors of low bone mass in the patients on hemodialysis have been proposed including age and body mass index (BMI). Our current study explored the relationship between BMI, age, sociodemographic status, and BMD among postmenopausal women on hemodialysis.
Methods: This study enrolled postmenopausal women on hemodialysis whose bone densitometry was checked and assessed with the age, BMI, and social status. Statistical analysis was performed in SPSS software.
Results: Sixty participants with a mean ± standard deviation (SD) of age of 57.00 ± 10.63 years were enrolled. After adjustment of sex and age, normal-weight women had 2 times the prevalence of low bone density compared to the obese women [prevalence ratio (PR) = 2, 95% confidence interval (CI): 1.4–2.8]. For osteoporosis, the PR was also twice higher for the women with normal BMI (PR = 2, 95% CI: 1.3-2.8) and 1.6 times higher for the overweight group than the women in the obese group (PR = 1.6, 95% CI: 1.3-2.4).
Conclusion: Among the women on hemodialysis, obese women have lower prevalence of osteoporosis than normal-weight cases.
Asymmetric Bilateral Hip Fracture-Dislocation: A Case Report and Literature Review
Authors: Mortazavi Seyed Mohammad Javad , Mazzochy Hamed , Ghasemi Mohammad Ali , Yaseen Khan Furqan Mohammed
Published: July 2020

Background: Asymmetric bilateral hip dislocation is a rare condition, especially when it is accompanied by a bilateral femoral head fracture.
Case Report: A 28-year-old man who sustained a motor vehicle accident, was presented to the our center (Imam Khomeini Hospital Complex) with asymmetric bilateral hip fracture-dislocation. In the initial step, closed reduction was performed, followed by bilateral open reduction and fixation of the femoral head fragment by screws. The results were satisfactory after 5 years of follow-up.
Conclusion: Although rare, paradoxical femoral head fracture should be considered in patients with hip dislocation. We recommend our therapeutic approach in a similar situation.
An Overview of Immunogenetic in Celiac Disease
Authors: Aflatoonian Majid
Published: July 2020

Introduction: Celiac disease is an autoimmune disease caused by persistent intolerance to gluten, which is causedin people who are genetically predisposed.The disease presents with atrophy of the small intestinal mucosa and gastrointestinal and extra-gastrointestinal manifestations.Environmental factors like gluten and genetic factors such as HLA and non-HLA genes are involved in causing the disease.Mucosal atrophy results from an adaptive and innate immune response to gluten. T-helper, interleukin 15 and tumor necrosisfactor-alpha have a central role in this process. Recognize the risk of genetic factors and inflammatorymechanisms will help diagnose and treat the disease.
Relation between Concentration of Pollutants and Some Climatic Parameters on Cardiovascular and Respiratory Disease Mortality in Shiraz
Authors: Omidvar Kamal , Shahaeian Sepideh , Amiri Esfandegheh Mahbobeh
Published: July 2020

Introduction: Industrialization and the growing of urbanization have increased the amount of contamination and have a devastating impact on the population health; the aim of this study was the relationship between pollutants and some climatic parameters on mortality of heart and respiratory diseases in Shiraz
Methods: The study was an analytical one. Firstly, daily data on climate elements (temperature, humidity, pressure, wind) from Shiraz Meteorological Office (2004-2014), daily information on air pollutants (CO, PM, NO2, SO2, O3) from Shiraz General Environment Department and cardiovascular and respiratory mortality rates from Shiraz University of Medical Sciences was collected, respectively. Data were analyzed using software SPSS ver. 22; statistical methods and correlation coefficients of monthly, seasonal and monthly averages and mortality rates were investigated.
Results: Results of this study indicated that there was a significant correlation between the parameters of the climate (humidity, pressure, temperature and wind) and deaths from cardio - vascular and respiratory diseases at the level of 0.99 and 0.95 (**=P<0/01, *=P<0/05). There was a statistical difference between the mortality rates in different seasons in Shiraz and the mortality rates caused by the cardio vascular and respiratory diseases were relatively more sensitive to climate parameters.
Conclusion: In general, during the statistical period, no polluted day was observed in polluted O3, NO2 in Shiraz City, relationships between other pollutants and mortality rates were significant. This correlation is shown by a 1-5 day delay for pollutants of CO, PM10and 6-10 days for pollutants of SO2.
Effect of Metformin on Some Cognitive Functions in Old Rats
Authors: Pak-Hashemi Mohammad , Hassanipour Mahsa , Kaeidi Ayat , Saeed-Askari Pooya , Fatemi Iman , Rahmani Mohammad Reza , Hakimi Elham , Hassanshahi Jalal , Ehsani Vahid , Taghipour Zahra , Khademi Marzieh , Allahtavakoli Mohammad
Published: July 2020

Introduction: Aging is a complex process and is considered as a risk factor for many diseases such as hypertension, Alzheimer, cancer, depression and anxiety. Recently, it has been shown that metformin, an anti-diabetic drug, has important neurological effects such as preventing memory loss, stroke, anxiety, inflammation and seizures. Therefore, the aim of this study was investigating the effects of metformin on some cognitive factors in elderly male rats.
Methods: 24 rats (22 months) were randomly divided into 3 groups (n=8). The first group was the control group that received water orally, the second group received metformin 1 mg/kg orally and the third group received metformin 10 mg/kg orally. After treatment for 40 days (once daily), behavioral tests, including Y-maze, elevated plus maze and depression test were performed on animals. Results were analyzed using GraphPad Prism version 6 and One-way ANOVA followed by Tukey-post hoc test.
Results: The results of this study showed that metformin at a dose of 10 mg/kg significantly reduced anxiety (P<0.001) and depression (P<0.001) in older animals. Metformin at a dose of 1 mg/kg failed to improve aging-related disorders in this model.
Conclusion: Metformin at a dose of 10 mg/kg can reduce the quality of life by reducing anxiety and depression.
Comparison of work environment air quality and application of geostatistic technique in the spatial distribution of PM2.5 and PM10 in a number of industrial workshops
Authors: Shojaee Barjoee S , Azimzadeh HR
Published: July 2020

Introduction: Air quality in industrial workshops is affected by various harmful chemical agents. Purpose of this study was to compare work environment air quality in a number of industrial workshops based on the mass concentration and number of suspended particles in air and application of Kriging geostatistical method in industries.
Materials and Methods: This observational study was carried out in four workshops including cuprous waste separation works, rolling and cutting, casting and copper smelting, manufacturing aluminum products and double-glazed glass production. Using particle mass counter sampler of Tes 5200 model, mass concentration and number concentration of suspended particles in row of different diameters were measured. The spatial distribution map of PM2.5 and PM10 in each of workshops was prepared using Kriging geostatistic method in GIS environment Version 10.5.
Results: The highest mass concentration (8.42 mg/m3) and number concentration (445058 Particle/lit in differential mode and 885446 Particle/lit in cumulative mode) were measured in the manufacturing aluminum products workshop. The highest mass concentration and number concentration of suspended particles were obtained for row diameters of 10 µm and 0.5 µm, respectively. Interpretation of Kriging maps showed that various areas of the industries such as radiation furnace, scrap press, aluminum smelter, sieve, diamond machine, glass furnace and ingot molds had the highest frequency of PM2.5 and PM10.
Conclusion: Engineering control actions such as installation of ventilation systems in halls and design and installation of a local hood in the entrance sections of the aluminum smelting furnace and sieve in manufacture of aluminum products workshop and copper ingot molds in casting and smelting workshop is essential for improved air quality.
Determining optimal risk assessment model in construction projects (Case study: steel plant construction project
Authors: Salajegheh S , Akhavan A , Hajihosseini A
Published: July 2020

Introduction: Identifying occupational hazards and managing occupational safety and health risks has been the most important mission and responsibility of the health and safety management system in organizations and adopting coded plans to achieve this is the key to continuously improving this system and promoting it. The aim of the present study was to determine the optimal risk assessment methodology in development projects.
Materials and Methods: This was a descriptive-analytic research In this research, using previous research studies and collecting expert opinions, the most important criteria for selecting a specific risk assessment methodology, and then using one of the three most-used techniques is an important activity in the steel making industry and risk assessment. Then, the decision matrix is based on the strengths and weaknesses of the models. The prioritization of these three methods is done using the hierarchical analysis decision method.
Results: In this paper, five key factors, the degree of application in identifying hazards, usability in different stages of risk assessment, reliability, ease of use, and training needs and costs, are identified as the most important criteria for choosing a risk assessment technique and the FMEA method was considered as the best  Risk Assessment Method.
Conclusion: FMEA methodhas been introduced with regard to its capabilities as an optimal risk assessment method for contruction projects.
Investigating the effective annual dose of radiation angiography department of Afshar Hospital in Yazd and providing radiation protection strategies to better manage the dose received by staff
Authors: Asgari A , Parach AA , Mirmohammadi SJ , Mehrparvar AH , Daneshian E , Nekoofar Z
Published: July 2020

Introduction: Due to the increasing use of angiography procedures and the higher risk of deterministic and stochastic effects for radiation workers of these sections than other radiological procedures, radiation safety is very important among angiography staff. Therefore, this study aimed to obtain the effective dose of angiography staff, compare them with the standard dose limit, and finally outline the strategies for occupational dose reduction in angiography.
Methods: In this study, the report of film dosimetry of angiography staff was studied and the effective periodic and annual doses of 34 radiographs were reported from the year 2015 to 2018. The relationship between effective dose and body mass index, work experience, gender and age of staff was also evaluated.
Results: The results showed that the average effective dose of the physicians, nurses and radiographers in 2 months period were 0.2 mSv and their average annual effective dose were 1.6, 1.2 and 1.2, respectively. In addition, there were no significant relationship between effective dose and work experience, age, sex and BMI of the radiation workers.
Conclusion: The effective dose of radiation in this study is less than the annual dose.. Low effective doses do not make their radiation protection less important because this reduction can be due to radiation protection by personnel in this ward. Therefore, as far as possible, radiation protection measures should be taken to reduce the radiation exposure of catheterization lab staff. In these radiologists thyroid protection, eyes, gonads, and the organs that are usually outside the lead apron is of great importance.
Cognitive relationship between vehicle color and the type of accidents leading to death and injury in driver
Authors: Moradi Bontoot S , Halvani GH , Abarghouei N , Jambarsang S , Fallah H , Anoosheh V , Samsami B
Published: July 2020

Introduction: Annually, many people die or suffer from irreparable injuries in road accidents worldwide. One of the causes of accidents is drivers, cognitive factors and the vehicle color is one of the factors that affect the cognitive performance of the drivers. Therefore, this study aimed to investigate the relationship between vehicle color and type of accidents leading to death and injury.
Materials and Methods: This descriptive cross-sectional study was performed on 300 randomly selected cases of accidents in Kerman. Information including the manner of accident, name and color of vehicle, location, cause, time, area of protection, weekday, season and type of accident were collected from traffic police and traffic department statistics and analyzed by using SPSS software.
Results: The results of the study showed that most of the accidents occurred during daylight hours. Motorcycle, black and white vehicles had the highest and yellow and beige vehicles had the least frequency. There was no significant difference between vehicle color (dark and light) and other variables with the type of accidents leading to the driver's death and injury.
Conclusion: According to the results of this study, no significant relationship was observed between vehicle color (dark and light) and the type of accidents leading to death and injury on. One of the reasons seems to be the difference between the methods of statistical analysis. Further studies are needed to investigate the relationship between the type of accidents and vehicle color.
Survey the level of well-being and Psychometric characteristics of hospital nurses’ well-being at work scale
Authors: Soltani Shal R , Saadatbin Javaheri F , Zebardast A
Published: July 2020

Introduction: Mental health problems is common among nurses, because they have to deal with to workplace stresses such as work-rest cycle problems, overload responsibility, financial problems, lack of vacation time, pressures of work, patient communication frameworks  and painful experiences of patients. These factors can decrease their wellbeing, but there is not brief and practical scale to assess psychological resiliency among nurses. Therefore, the aim of the present study was to evaluate the psychometric properties of the hospital nurses’ well-being at work scale.
Materials and Methods: This cross-sectional study was conducted on 194 nurses. The hospital nurses’ well-being at work was administered. The hospital nurses’ well-being at work is composed of 67 items and psychometric properties were examined through the Face validity, Content Validity, Concurrent validity, Construct validity. The data were analyzes by SPSS software.
Results: Face and content validity were approved by five psychologists. The KMO index and Bartlett's Cruity Index indicated that correlation matrix was suitable for performing exploratory factor analysis. Factor analysis with Principal Component Analysis extracted one factor with 67.06% total variance. Internal consistency was confirmed by a Cronbach’s alpha of 0.957. According to the findings of the present study, 2.1% of nurses experienced very low well-being, 6.7% experienced low, 66.6% experienced moderate and 22.7% experienced high one.
Conclusion: This study showed that the hospital nurses’ well-being at workplace had appropriate psychometric properties and is a valid and reliable screening index to measure well-being of nurses. This index could facilitate the assessing Well-Being in brief and practical way among nurses.
Newton’s Third Law is not a Dogma but a Computational Hypothesis
Authors: Arinchev S.V.
Published: July 2020

Experimental modal analysis is an important stage in the development of a flying vehicle structure. In the experiment, the eigenfrequency of the structure is identified by a corresponding resonance peak of its amplitude-frequency response characteristic. Different sensors in the vibration machine provide different amplitude-frequency response characteristics. The resonance peaks obtained through different sensors for one and the same eigenfrequency of the structure are located with a frequency shift of approximately 1 Hz. This frequency-shift effect is an obstacle for the experimental modal analysis of structures with closely located oscillation modes. This paper explains the frequency-shift effect using the particle approach. A particle is a point mass, and a structure is a system of particles connected by springs, with each particle associated with its own structural model. Each particle has a “right” for its own resonance and “lives” in its own parallel reality. Each particle is associated with an acceleration sensor. The number of simultaneously considered models is equal to the number of sensors. The obtained modal-analysis results are related only to the corresponding particle. Newton’s third law of the particle interaction is not used in full when assessing the particles’ interaction. The action and reaction forces are still applied to different particles along the same line in the opposite directions, but these forces are different. Modal-analysis simulation is limited to the 2-DOF and the 3-DOF oscillation models.
Intestinal fatty acid binding protein as a marker of damage intestinal barrier in children with burn injury
Authors: Костина Ольга Владимировна , Галова Елена Анатольевна , Ашкинази Владимир Израильевич , Стрелкова Ирина Геннадьевна
Published: July 2020

Introduction. Intestinal fatty acid binding protein (I-FABP) can serve as one of biomarkers of the damage to the intestinal mucosa in burned children occupying a special place among the complications and causes of their death. Materials and methods. There were examined 24 children with burns from 20% to 80% of the body surface. Blood serum I-FABP and lactate levels were determined during both the acute period of burn disease and septicotoxemia. Results. In the acute period wide variations in I-FABP values (from 22.67 to 385.18 pg/ml) were demonstrated. During the septicotoxemia I-FABP level increased by an average of 1.4 times, reflecting intestinal cell damage. Children with a burn area >40% had a higher I-FABP level during all follow-up periods compared to children with a burn ≤ 40%. In the acute period there was a positive correlation between the lactate and I-FABP levels. During the septicotoxemia, despite the increase of lactatemia and I-FABP level, this relationship was absent. The maximum increase in I-FABP level was observed in patients with complications of burn disease on the part of the intestine (duodenitis, bulbitis, stress ulcers) and with the development of sepsis. Conclusion. It seems promising to further study this biomarker in order to timely diagnose increased intestinal permeability in children with thermal trauma and develop proper treatment tactics to prevent possible complications, such as intestinal erosive and ulcerative bleeding, the development of bacterial translocation, sepsis and multi-organ failure syndrome.
Current issues of diagnosis and treatment of neonatal omphalocele
Authors: Щукина Анна Александровна , Мокрушина Ольга Геннадьевна , Гурская Александра Сергеевна , Дьяконова Елена Юрьевна
Published: July 2020

The review of topical issues of diagnostics and treatment of malformation of the anterior abdominal wall - omphalocele in newborns is presented. Currently, there are no specific, recognized criteria acceptable for the maintaining and further managing pregnancy, delivery and treatment of children with omphalocele. Prenatally, the possibility of predicting the tactics of surgical treatment and postoperative management of a newborn with omphalocele is not taken into account. In the choice of tactics of treatment of this category of patients there is a need to consider many factors, namely: the data for the antenatal diagnosis of the defect, duration of respiratory support at the stage of preparation for surgery, age at the time of surgical treatment, the size of the hernia SAC, and the size of the liver in the hernia SAC. These criteria are necessary to determine the possibility of radical surgery for the anterior abdominal wall or stage-by-stage treatment with the creation of a temporary abdominal cavity, with preliminary gradual immersion of the evented organs into the abdominal cavity under the control of the child’s hemodynamic and respiratory parameters, with the dynamic control of the occurrence and progression of pulmonary hypertension under the ultrasound control. To date, a unified approach has not been developed in the surgical treatment and postoperative care of newborns with omphalocele. The use of a variety of methods of surgical correction and their modifications reveals extensive potential for the treatment of different form of exomphalos, but leads to the fact that some of these techniques find their applications in a single universally accepted treatment of this condition. The lack of unified standards of prevention and organization of treatment approaches for newborns with various forms of omphalocele makes this problem very relevant. When preparing a literary review, such databases as PubMed, MedLine, CyberLeninka, and RSCI were used.
N.I. Pirogov – surgeon, scientist, and teacher: a look from the 21st century
(on the 210th anniversary of the great Russian doctor). Part 3
Authors: Иванюшкин Александр Яковлевич , Фисенко Андрей Петрович , Смирнов Иван Евгеньевич
Published: July 2020

The final part of the scientific review of the life and creative activity of N.I. Pirogov presents information about his pioneering work in the field of “anesthesia on the battlefields and in hospitals”. Using the mask invented by himself, he performed many operations under ether anesthesia directly at the scene of hostilities and showed the advantages of analgesia, especially in significant in the conditions of a «traumatic epidemic», as N. I. Pirogov called the war. A brilliant surgeon opposed ascetic experience to the large-scale tragedy of the war. N. I. Pirogov’s works on military field surgery have become the heritage of mankind, the scientific basis of military medical education all over the world and are such a contribution to the history of medicine that should be evaluated on the scale of the development of civilization as a whole. In 1856, there was began a new stage of Pirogov’s creative activity, aimed at solving issues of public life, education and upbringing. He paid special attention to the issues of improving University education, designed both to provide a high level of scientific training of specialists and contribute to increasing the scientific and spiritual potential of the country. The distinguished surgeon ended his career on November 23, 1881. The memory of him and his brilliant work for the benefit of our country is carefully preserved.
Analysis of the state of the cardiorespiratory system of rural schoolchildren in the conditions of the health center
Authors: Белкина Елена Игоревна , Кузнецова Татьяна Анатольевна
Published: July 2020

The purpose of the work is the analysis of the possibilities of diagnostic equipment of the field health center for assessing the state of the cardiorespiratory system in rural schoolchildren. Materials and methods. There were examined 319 children aged 6-17 years, there was performed analysis of the possibilities of spirography, pulse oximetry, electrocardiography, measurement of blood pressure and carbon monoxide levels in expired air using a smokerlyzer. Results. In the conditions of a field health center for rural schoolchildren there are acceptable methods for measuring blood pressure levels, pulse oximetry, and determining the facts of smoking by interviewing children. The use of electrocardiography, USB spirograph and Smokerlyzer is insufficient, because it does not allow identifying life-threatening arrhythmias, adequate assessing respiratory function with necessary accuracy, and the motivation of students to smoking cessation.
Klebsiella pneumoniae: microbiological characterization, antimicrobial resistance, and virulence
Authors: Shamina Olga V. , Samoylova Ekaterina A. , Novikova Irina E. , Lazareva Anna V.
Published: July 2020

Klebsiella pneumoniae (KP) represents one of the main causative agents of opportunistic infections. KP associated infectious diseases can be local, for example, pneumonia, and generalized, including severe, often life-threatening conditions (meningitis, sepsis). Besides the chromosomal genome with a variety of different genetic loci, KP contains an additional plasmid genome which endues it with important biological properties. That’s why KP strains can be opportunistic, hypervirulent, and resistant to antimicrobials. In this literature review, literature data on the molecular resistant mechanisms, virulence factors and infectious diseases caused by KP is discussed.
Short-term media effects include the alterations of sensitivity towards the real violence from the past
Authors: Tukaiev Sergii , Havrylets Yurii , Rizun Volodymyr , Grimm JuÌˆrgen , Enzminger Andreas , Zyma Igor , Makarchuk Mykola
Published: July 2020

The purpose of this study was to identify the impact of TV news on the perception and processing of emotional footage of a historical documentary. We noted that the emotional frames taken from TV news stories are relatively weak emotional stimuli compared to the emotional frames of historical documentary. The subjects exposed to the pre-stimulus evaluated the Holocaust pictures as more unpleasant and more activating than those not exposed it. The event-related potentials (ERP) recorded during the presentation of the negative (historical) images had various amplitudes of oscillations due to the preliminary affective impact of TV news footage. The amplitude of the frontal ERP component that related to the decision-making (P300) was bigger in the group without preliminary exposure to the emotional TV news frames due to the reduced sensitivity to the content of images. In this case, the historical images attracted less attention and demanded less emotional effort for emotional evaluation of visual information, analysis, retrieval of information from memory and semantic processes, namely searching for the meaning of the pictures (occipital P300 and the late positive potential). Short-term media effects include alterations of sensitivity towards the emotional content of visual information.

 

Keywords: Emotion; violence; Holocaust TV news;
USO DO BIODIGESTOR NA SUINOCULTURA: UMA ALTERNATIVA À SUSTENTABILIDADE AMBIENTAL NA REGIÃO DO MACIÇO DE BATURITÉ, CEARÁ
Authors: Alcócer Juan Carlos Alvarado , Pinto Olienaide Ribeiro de Oliveira , Oliveira Jangirgledia De , Silva Maria Elanny Damasceno , Lima Ari Clecius Alvez de
Published: July 2020

A suinocultura é significativa do ponto de vista social e econômica. Sua exploração é apontada pelos órgãos ambientais como uma atividade causadora de degradação ambiental gerando grande quantidade de resíduos. No Maciço de Baturité uma parte de sua população rural sobrevive da exploração da suinocultura e os dejetos gerados frequentemente são desperdiçados. Nota-se escassez de trabalhos que apresentem a solução total ou parcial do problema ambiental gerado pela suinocultura em propriedades rurais no Maciço. O objetivo desse trabalho é mostrar que o uso do biodigestor na suinocultura é uma alternativa sustentável para a região do Maciço, podendo contribuir para o controle das emissões de gases de efeito estufa, redução dos impactos ambientais e produção de energia renovável e adubo orgânico. Realizou-se um levantamento dos biodigestores em propriedades rurais de suínos dos municípios do Maciço. Foram entrevistados agricultores para saber a destinação dada aos produtos da digestão anaeróbia (biogás e biofertilizante) e observaram-se os impactos ambientais gerados por resíduos animais, além de, realizar análise dos gases do biogás. Portanto, a produção do biogás e do biofertilizante pelo sistema de biodigestão agrega valor à propriedade rural, tanto pelo fato da geração de energia renovável quanto à reciclagem de nutrientes e saneamento ambiental.
Pemikiran Zakiah Daradjat Antara Kesehatan Mental dan Pendidikan Karakter
Authors: Indah Sri
Published: July 2020

This library research aimed to find the point of integration between mental health and character education. The dynamics of Islamic study is presecuted to develop the paradigm unity of Islamic study, exact sciences and humanities. This research try to contribute pedagogic by intergrating mental health science with Tafseer. Hopefully the intergration of mental health science gives the steady in conception in understanding of human dynamics. Integration with Tafseer meant to find originality in Islam. So this research is able to find the concept of comprehensive, holistic, in depth and applicable in the world of education. This is a qualitative research that used informaton from Al-Qur’an, Al-Hadis, books of mental health experts and character education experts. The documentation method was used to collect the data of research. This research try to reveal and to ta’shil the understanding of mental, mental health and tazkiyah nafs then aplicate this understanding into character education. The result of the research indicates that tazkiyah nafs is the point of integration between mental health and character education for building healthy and characteristic individual
Kepemimpinan dalam Perspektif Islam
Authors: Olifiansyah Muhammad , Hidayat Wahyu , Dianying Bimansyah Putra , Dzulfiqar Muhammad
Published: July 2020

A leader is someone who has a great responsibility in the organization for social life, being a leader must have a good relationship in cultural life so that it can be used as an example by its members. In Islam itself it is conveyed to the Ummah to become a leader in accordance with the existing Shari'a in the teachings of Islam, which subsequently leads to Islamic Leadership. Islamic leadership is a balance of leadership with the concept of the world and the hereafter, the task of leadership is not only a task that is held only for members, but also in the presence of Allah SWT. Allah has sent an Apostle who can be an example for Muslims to carry out Islamic Leadership as the Prophet Muhammad. Islamic leadership prioritizes the values ​​put forward by Islam and also everything that is done because it expects God's blessing. Islamic leadership is more than part of the goals taken while in organizational leadership in general, support the strengthening of the establishment of Islamic order in the organization. Islamic leadership supports absolute leadership or leadership that is authorized, this leadership has a distinct characteristic of leadership in general.
PENGARUH MODEL PEMBELAJARAN PROJECT BASED LEARNING TERHADAP KREATIFITAS BERPIKIR DAN LITERASI SAINS SISWA SMAN 1 GERUNG TAHUN 2018/2019
Authors: Raehanah Raehanah , Khatimah Husnul , Suhirman Suhirman
Published: July 2020

Penelitian ini bertujuan untk mengetahui pengaruh model pembelajaran project based learning terhadap kreatifitas berpikir dan literasi sains siswa SMAN 1 Gerung Tahun 2018/2019 pada materi koloid. Penelitian ini merupakan penelitian quasi-eksperimen,dengan  desain pretest-postest group kontrol. Pengambilan sampel menggunakan teknik sampling jenuh dengan jumlah sampel 67 orang. Data kreatifitas berpikir diambil dengan tes pilihan ganda beralasan, dan data literasi sains diambil dengan tes pilihan ganda biasa. Uji hipotesis menggunakan MANOVA. Berdasarkan hasil analisis, kesimpulan sebagai berikut; 1) Ada pengaruh yang signifikan model pembelajaran project based learning terhadap literasi sains secara multivariat (sig=0,022<0,05); 2) Ada pengaruh yang signifikan model pembelajaran project based learning terhadap kreativitas berpikir dan literasi sains (sig=0,033<0,05); 3) Ada pengaruh yang signifikan model pembelajaran project based learning terhadap literasi sains (sig=0,047<0,05).
PENGARUH VARIASI KONSENTRASI JAGUNG TERHADAP KUALITAS NATA DE CORN
Authors: Sulistiyana Sulistiyana , Jayadi Edi M. , Hasanah Uswatun
Published: July 2020

Nata adalah produk kaya serat yang dibuat dari berbagai media dengan persyaratan cukup sumber karbon, nitrogen, pH dan suhu. Jagung kaya akan vitamin A, B, dan E, Thiamin, Niacin, Pantothenic Acid, dan folat. Vitamin dan Niacin mendorong pertumbuhan sel. Panthothenic Acid penting untuk lipid, protein, dan metabolisme karbohidrat dalam tubuh. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi jagung terhadap kualitas nata de corn yaitu; rendemen, ketebalan, dan kadar air. Penelitian ini menggunakan penelitian eksperimen dengan pendekatan kuantitatif. fermentasi dilakukan pada suhu lingkungan selama 13 hariengan variasi konsentrasi 0%, 10%, 20% dan 30%. Penelitian menggunakan pengulangan sebanyak 6 kali. Pada penelitian ini konsentrasi jagung berpengaruh nyata terhadap ketebalan dan kadar air tetapi tidak berpengaruh nyata pada rendemen nata de corn. Konsentrasi optimum pada analisis kualitas nata de corn ini adalah 20% dengan nilai rendemen 86,37%, ketebalan 0,573 cm dan kadar air 84,466%.

KATA KUNCI: Nata De Corn, Acetobacter xylinum, Jagung, Fermentasi
Measurement of the Radius of Metallic Plates Based on a Novel Finite Region Eigenfunction Expansion (FREE) Method
Authors: Huang Ruochen , Lu Mingyang , Zhang Zhijie , Zhao Qian , Xie Yuedong , Tao Yang , Meng Tian , Peyton Anthony , Theodoulidis Theodoros , Yin Wuliang
Published: July 2020

Eddy current based approaches have been investigated for a wide range of inspection applications. Dodd-Deeds model and the truncated region eigenfunction expansion (TREE) method are widely applied in various occasions, mostly for the cases that the sample is relatively larger than the radius of the sensor coil. The TREE method converts the integral expressions to the summation of many terms in the truncated region. In a recent work, the impedance of the co-axial air-cored sensor due to a plate of finite radius was calculated by the modified Dodd-Deeds analytical approach proposed by authors. In this paper, combining the modified analytical solution and the TREE method, a new finite region eigenfunction expansion (FREE) method is proposed. This method involves modifying its initial summation point from the first zero of the Bessel function to a value related to the radius of the plate, therefore makes it suitable for plate with finite dimensions. Experiments and simulations have been carried out and compared for the verification of the proposed method. Further, the planar size measurements of the metallic circular plate can be achieved by utilising the measured peak frequency feature.
Channel Waveguides in Lithium Niobate and Lithium Tantalate
Authors: Lu Yi , Johnston Benjamin , Dekker Peter , Withford Michael , Dawes Judith M.
Published: July 2020

Low-loss photonic waveguides in lithium niobate offer versatile functionality as nonlinear frequency converters, switches, and modulators for integrated optics. Combining the flexibility of laser processing with liquid phase epitaxy we have fabricated and characterized lithium niobate channel waveguides on lithium niobate and lithium tantalate. We used liquid phase epitaxy with K2O flux on laser-machined lithium niobate and lithium tantalate substrates. The laser-driven rapid-prototyping technique can be programmed to give machined features of various sizes, and liquid phase epitaxy produces high quality single-crystal, lithium niobate channels. The surface roughness of the lithium niobate channels on a lithium tantalate substrate was measured to be 90 nm. The lithium niobate channel waveguides exhibit propagation losses of 0.26 ± 0.04 dB/mm at a wavelength of 633 nm. Second harmonic generation at 980 nm was demonstrated using the channel waveguides, indicating that these waveguides retain their nonlinear optical properties.
Novel Hollow Fiber Membranes of PCL and PCL/Graphene as Scaffolds with Potential to Develop in vitro Blood-brain Barrier Models
Authors: Mantecón-Oria Marián , Diban Nazely , Berciano Maria T. , Rivero Maria J. , David Oana , Lafarga Miguel , Tapia Olga , Urtiaga Ane
Published: July 2020

There is a huge interest in developing novel hollow fiber (HF) membranes able to modulate neural differentiation to produce in vitro blood-brain barrier (BBB) models for biomedical and pharmaceutical research, due to the low cell-inductive properties of the polymer HFs used in current BBB models. In this work, poly(ε-caprolactone) (PCL) and composite PCL/graphene (PCL/G) HF membranes were prepared by phase inversion and were characterized in terms of mechanical, electrical, morphological, chemical, and mass transport properties. The presence of graphene in PCL/G membranes enlarged the pore size and the water flux and presented significantly higher electrical conductivity than PCL HFs. Biocompatibility assay showed that PCL/G HFs significantly increased C6 cells adhesion and differentiation towards astrocytes, may be attributed to their higher electrical conductivity in comparison to PCL HFs. On the other hand, PCL/G membranes produced a cytotoxic effect on the endothelial cell line HUVEC presumably related with a higher production of intracellular reactive oxygen species induced by the nanomaterial in this particular cell line. These results prove the potential of PCL HF membranes to grow endothelial cells and PCL/G HF membranes to differentiate astrocytes, the two characteristic cell types that could develop in vitro BBB models in future 3D co-culture systems.
Demanding of Lassa Fever: Reducing its Risk as an Infectious Disease
Authors: Aborode Abdullahi Tunde , Adesewa Victor Adegbile , Ayomide Oni Ebenezer , Olarenwaju Samuel Ogunsola
Published: July 2020

In recent years, Lassa fever has been announced as an infectious disease in the world, a few imported cases have been accounted for in various pieces of the world and there are developing worries of the possibilities of Lassa fever Virus as an organic weapon. Regardless of its assaulting impact, no substantial arrangement has been created to reduce the hazard of the ailment, about a large portion of 10 years after identifying it. A Review based on the documents from the literature search on PubMed, Scopus, Goggle Scholar and Science direct. Out of these, the final 16 articles that met the criteria were selected. Relevant information on epidemiology, the burden of management and control were obtained. Timely and effective containment of the Lassa fever disease in Lassa village four decades ago could have minimized the devastating effect and threats posed by this illness in the West African sub-region and indeed the entire globe. That was a hard lesson calling for much more proactive measures towards the eradication of the illness at primary, secondary, and tertiary levels of health care. Hence, the paper is aimed at appraising the threats associated with Lassa fever disease; its demands on curtailing the menace of the epidemic, and recommendations on important focal points.
Self Seed Production by Farmers Protect Their Rights and Enhance Their Sovereignty
Authors: Kushwaha Ujjawal
Published: July 2020

Farmer’s right and their sovereignty is an important issue related with intellectual property rights and agrobiodiversity management. To boost farmer’s right, a conceptual hypothesis is proposed where they choose either a new high yielding variety or the existing one and apply conventional breeding approaches to select the seed for next years in their own fields. Although farmers produce seeds traditionally from several years, they have not been guided with scientific discipline to produce sufficient amount of quality seeds. This new concept suggests trained farmers can use breeding approaches to produce quality seed for their own use.