bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS PRIORITAS PENGELOLAAN KAWASAN KONSERVASI PERAIRAN PULAU AY-RHUN, PROVINSI MALUKU
Authors: Juliyanto Ervien , Zairion  , Krisanti Majariana , Susanto Handoko Adi
Published: January 2020

Prioritas perencanaan sangat penting ditentukan untuk menjadi acuan pengelola dalam meningkatkan efektivitas pengelolaan kawasan konservasi perairan. Penelitian ini bertujuan untuk menganalisis prioritas perencanaan pengelolaan kawasan konservasi perairan daerah (KKPD) Pulau Ay-Rhun menggunakan metode Jejaring Analitik (Analytic Network Process, ANP). Permasalahan dan solusi dalam penentuan prioritas pengelolaan ini dikelompokkan menjadi empat, yakni: cluster ekologi, ekonomi, sosial, dan kelembagaan dengan masing-masing sub-cluster berdasarkan hasil diskusi kelompok terfokus (Focus Group Discussion, FGD). Hasil analisis menunjukan bahwa masalah utama kawasan konservasi perairan Pulau Ay-Rhun adalah cluster ekologi. Sementara hasil analisis sub-cluster menunjukan bahwa permasalahan prioritas pengelolaan adalah: (1) cluster kelembagaan berupa kurangnya kapasitas dan kuantitas SDM dengan nilai 0,6711; (2) cluster sosial berupa kurangnya pemahaman terkait konservasi dengan nilai 0,6340; (3) cluster  ekonomi berupa ketidakstabilan harga jual hasil perikanan dengan nilai 0,5684; (4) cluster ekologi berupa penambangan pasir dan karang untuk material bangunan dengan nilai 0,4614. Mengingat sub-cluster suatu cluster dapat mempengaruhi elemen lain dalam cluster yang sama dan dapat pula mempengaruhi elemen pada cluster yang berbeda, maka rekomendasi prioritas strategi pengelolaan dalam meningkatkan efektifitas kawasan konservasi perairan Ay-Rhun adalah: (1) cluster ekonomi berupa optimalisasi pemanfaatan sesuai daya dukung dengan nilai 0,6137; (2) cluster ekologi berupa pembentukan zonasi dengan nilai 0,5484; (3) cluster kelembagaan berupa penyusunan kebijakan pengelolaan dengan nilai 0,5308; dan (4) cluster sosial berupa sosialisasi mengenai konservasi dengan nilai 0,4680.
MAXIMUM THERMAL TOLERANCE OF TROPICAL MARINE GASTROPODS, Haliotis squamata (Reeve 1846)
Authors: Suci An Nisa Nurul , Zamani Neviaty Putri , Bengen Dietriech Geoffrey
Published: January 2020

Data about maximum thermal tolerance in marine organisms are needed to prevent the extinction of species due to global warming. The aim of this study is determining the maximum lethal temperature of Haliotis squamata. In this study, H. squamata were placed in individual containers and exposed to 5 different levels of temperature (27°C, 28.5°C, 30°C, 31.5°C, and 33°C, n = 20). The temperature was raised 0.5°C per 12 hours starting from ambient conditions until target temperatures were reached. The mortality was monitored since animals moved to the individual containers. The results showed that the maximum thermal limit of H. squamata is 31.5°C and 33°C is the lethal temperature, the temperature level with the lowest survival rate (0.15). The IPCC predict that sea surface temperature will raise up to 4°C and monthly average sea surface temperature in Indonesia is around 26 – 31°C. That means in the next century average sea surface temperature could be more than the maximum thermal limit of H. squamata. Thus, early conservation is needed to protect H. squamata.
ASPEK BIOLOGI DAN PEMANFAATAN IKAN TENGGIRI PAPUA (Scomberomorus multiradiatus Munro, 1964) DENGAN ALAT TANGKAP JARING INSANG DI PERAIRAN MERAUKE DAN SEKITARNYA
Authors: Putri Pane Andina Ramadhani , Wagiyo Karsono , Suman Ali
Published: January 2020

Ikan tenggiri Papua (Scomberomorus multiradiatus) adalah ikan endemik Papua yang tertangkap hanya di sekitar perairan Merauke. Pemanfaatan ikan ini oleh masyarakat lokal dengan tingkat produksi mengalami peningkatan dari tahun ke tahun. Dalam pengelolaan populasi ikan tenggiri Papua diperlukan kajian ilmiah tentang aspek biologi dan pemanfaatannya dengan menggunakan jaring insang hanyut. Penelitian dilakukan selama 2 (dua) tahun yaitu Maret - Desember 2017 dan April -Desember 2018 dengan metode survei yang dibantu oleh enumerator secara bulanan. Data komposisi hasil tangkapan jaring insang hanyut dominan ikan demersal karena dioperasikan di perairan dangkal yang menyapu hingga ke dasar. Ikan tenggiri Papua hanya sekitar 6-10% dari total tangkapan dengan struktur ukuran dominan pada 40 cmFL (fork length) dan pola pertumbuhan allometrik positif. Nisbah kelamin ikan tidak seimbang dengan dominan jantan dibandingkan betina. Ukuran ikan yang pertama kali tertangkap semakin kecil ukurannya yaitu 32.08 (2017) menjadi 30.50 (2018) yang dapat menjadi indikasi bahwa ukuran ikan semakin kecil. Laju pertumbuhan (K) sekitar 0.64 yang menunjukkan laju pertumbuhan tergolong lambat dengan laju kematian akibat penangkapan (F) lebih tinggi dibandingkan kematian alamiah (M). Pemanfaatan ikan ini sudah mencapai E=0,70 atau 140% sehingga harus dilakukan pengurangan 40% dari upaya saat ini dan dengan mengembangkan kearifan lokal agar ikan endemik terjaga populasinya.
A EDUCAÇÃO DO CAMPO NO MST COMO FERRAMENTA DE CONSTRUÇÃO DA HEGEMONIA
Authors: Bicalho Ramofly , Leite Isabella De Mello
Published: January 2020

O presente artigo é fruto das pesquisas realizadas no Mestrado em Educação na Universidade Federal Rural do Rio de Janeiro (UFRRJ). Tem como objetivo central realizar um breve apanhado histórico das políticas públicas de educação do campo. Compreender sua notoriedade ao longo dos anos, em consonância com os conceitos Gramsciano. Importa ainda, conhecer como o Movimento dos Trabalhadores Rurais Sem Terra (MST) movimentou-se para conquistar tais políticas públicas, a partir dos anos 1990. Utilizamos, predominantemente, a pesquisa bibliográfica e documental. Concluímos que a educação do campo, como práxis libertadora, é utilizada no processo de compreensão das lutas e demandas educacionais defendida pelo MST. Ela dialoga com os gestos, desejos, valores e a luta pela terra, além de contribuir na construção de uma outra hegemonia que oriente sua base militante.
NOTÍCIAS SOBRE AS ESCOLAS DO CAMPO EM GOIÁS
Authors: Alves Amone Inacia
Published: January 2020

Esse artigo fruto de uma pesquisa de cunho bibliográfico, pretende apresentar como a imprensa goiana tem noticiado sobre o funcionamento das escolas do campo em Goiás, nos anos 2010. Há uma disputa hegemônica sobre como deve funcionar essas escolas, sendo que a imprensa assume um partido e é objetivo desse texto compreender essa origem. Compreendemos que apesar da escola ser um dos instrumentos utilizados pelo campesinato para a transmissão de seus valores e tradições, ela tem sido maculada por um projeto de poder, de dominação econômica e de derrota dessa classe frente aos desmandos do capital. Ela tem sido pensada não a partir das suas especificidades, mas a partir de um projeto de cidade. A imprensa no geral, quando apresenta notícias sobre as escolas, apoia-se nas seguintes categorias de análise: violência, precarização de contratos de professores, transporte escolar. Então é objeto desse texto mapear essas notícias, mostrando o retrato das escolas goianas, a partir da imprensa no Estado.
VEIAS ABERTAS PARA A PRIVATIZAÇÃO NA EDUCAÇÃO BRASILEIRA
Authors: Macedo Jussara Marques de , Motta Vânia Cardoso da
Published: January 2020

Este artigo resulta de pesquisas que buscam compreender os recentes encaminhamentos de políticas públicas de educação brasileiras, face ao processo da inserção do ethos empresarial na gestão das redes públicas de educação básica, no contexto da reforma da administração pública. Por meio de análise de documentos e de dispositivos legais, o artigo indica a configuração da correlação de forças políticas nos governos do Partido dos Trabalhadores. Aponta a ocorrência do que classifica como “união pessoal” entre governo, organizações da sociedade civil empresarial/acadêmicas e integrantes de movimentos sociais combativos, no período de 2007 a 2015, sob argumento de estar referendado pelos conceitos de Estado Ampliado e de Estado Educador de Gramsci. A análise indica a supremacia da lógica privatista empresarial como principal referência do conjunto das políticas públicas de educação básica implementadas neste período. É neste sentido que o artigo conclui que foram “abertas as veias” para a privatização da educação no país.
CURSO PRÉ-VESTIBULAR "UNIVERSIDADE PARA TODOS"
Authors: Sousa Erivan Coqueiro , Nunes Cláudio Pinto
Published: January 2020

O presente artigo aborda o curso pré-vestibular Universidade Para Todos (UPT), um projeto do governo do estado da Bahia, perante um movimento de educação popular que prepara estudantes de baixa renda para o acesso ao nível superior. Explana-se, ainda, sobre um curso Pré-Vestibular Social que iniciou, em 2002, no Campus XII, da Universidade Estadual da Bahia (UNEB), em Guanambi, Bahia, que serviu de referência para as discussões do Estado para criar o UPT. Trata-se de uma análise qualitativa baseada em fontes bibliográficas primárias e secundárias (leis e atas), entrevistas abertas realizadas com dois professores fundadores do Curso Pré-Vestibular Social de Guanambi. Os resultados demonstram que o projeto UPT é uma ação de caráter popular que contribui para o acesso ao nível superior, foi criado devido a diversas reivindicações sociais e teve como referência experiências predecessoras que alcançaram êxito.
LA EDUCACIÓN POPULAR EN PROCESO DE CONSTRUCCIÓN DEL ESTADO COMUNAL EN VENEZUELA
Authors: Ruíz Samuel H. Carvajal , Socorro Paulina E. Villasmil
Published: January 2020

O objetivo desta contribuição é refletir criticamente sobre os aspectos teóricos e práticos da educação popular no contexto da construção do poder popular na Venezuela. Enquanto algumas considerações teóricas e conceituais sobre essa proposta educacional são apontadas, as contribuições dos pedagogos venezuelanos para esse movimento também são recuperadas. Finalmente, registram-se algumas experiências no desenvolvimento de sua práxis no trânsito complexo do modelo rentista-petrolífero em vigor no país, para uma sociedade democrática, participativa e dirigente como fundamentos espirituais da sociedade comunal emergente.
EDUCAÇÃO POPULAR E EDUCAÇÃO DO CAMPO NA AMAZÔNIA
Authors: Hage Salomão A. M. , Corrêa Sérgio Roberto Moraes
Published: January 2020

O artigo reflete sobre a Educação Popular e a Educação do Campo, focando a Amazônia e as lutas dos movimentos sociais no atual cenário de retrocesso democrático no Brasil. Buscamos compreender o que as lutas dos movimentos sociais da Amazônia têm a contribuir para alagar a reflexão teórica e a ação política da Educação Popular e da Educação do Campo no Brasil e na Amazônia? Realizamos estudo bibliográfico e documental e pesquisa de campo junto ao Movimento da Educação do Campo na Amazônia Paraense. Os resultados evidenciam que o governo Bolsonaro tem colocado a Amazônia brasileira na rota mais intensa do capitalismo dependente e neoextrativista, reproduzindo o par histórico modernização-colonização; todavia, os movimentos sociais de povos tradicionais e camponeses resistem em defesa de outros marcos civilizatórios. No caso em estudo, emergem ações de combate ao fechamento de escolas no campo e tensões com relação às formas de oferta do Ensino Médio nos territórios rurais.
DESENVOLVIMENTO E HEGEMONIA PARA UMA EDUCAÇÃO PÚBLICA E POPULAR NO CAPITALISMO PERIFÉRICO
Authors: Almeida Everton Werneck de
Published: January 2020

Reflexão sobre os limites e potencialidades da construção de uma educação pública e popular tendo em conta nossa inserção dependente no âmbito dos sistemas político e econômico mundiais. Que tipo de desenvolvimento e inserção na divisão internacional do trabalho favoreceria ou constrangeria a construção de uma educação que, além de pública, fosse também popular? Reflete-se sobre o conceito de hegemonia, crucial para compreender que o desenvolvimento e concomitante inserção de um país no sistema político e econômico mundial é também opção política, escolha necessariamente alicerçada sobre relações de conflito ou aliança entre distintas classes ou grupos sociais. Conclui-se que a construção da educação pública e popular em nosso país, além de determinado tipo de desenvolvimento, requer, concomitantemente, a construção de uma hegemonia, para dar àquele desenvolvimento sustentação política e social.
Analisis Penambahan Carboxymethyl Cellulose terhadap Edible Film Pati Umbi Garut sebagai Pengemas Buah Strawberry
Authors: Putri Rr. Dewi Artanti , Sulistyowati Desi , Ardhiani Tias
Published: January 2020

Edible film dari pati merupakan strategi penyusunan kemasan makanan bersifat biodegradable. Film dari  pati memiliki kekurangan sebagai kemasan makanan karena realtif mudah robek, sehingga perlu penambahan plasticizer gliserol agar lebih elastis. Sedangkan untuk meningkatkan kuat tarik dan perbaikan struktur permukaan digunakan turunan selulosa yaitu CMC (Carboxy Methyl Cellulose). Umbi garut berpotensial sebagai bahan baku edible film dengan kandungan pati 86,1%. Dalam penelitian ini dilakukan sintesis edible film dengan penambahan konsentrasi CMC bervariasi (0%, 5%, 10%, 15%, 20% b/b). Selanjutnya dilakukan karakterisasi pengaruh konsentrasi CMC pada ketebalan, ketahanan, kelarutan dalam air, kuat tarik, perpanjangan, dan elastisitas. Edible film dengan penambahan 20% CMC menunjukkan karakteristik ketebalan (0,144 mm), ketahanan terhadap air (93,75%), dan kelarutan dalam air (34%) terbaik. Edible Film dengan penambahan CMC 10% menunjukkan karakteristik kuat tarik (3,5597 Mpa) dan elastisitas (25,85 Mpa) terbaik. Nilai perpanjangan terbaik (18,3%) dengan penambahan CMC 15%. Edible film yang telah diaplikasikan pada buah strawberry dapat memperpanjang umur simpan buah hingga 4 hari.
Don Mosse. Cirujano real y poeta del Cancionero de Baena
Authors: Gutwirth Eleazar
Published: January 2020

El poema de Don Mosse ibn Zarzal –en contraste con otros– ofrece una fecha precisa: el nacimiento del infante Juan –después Rey Juan II de Castilla-Leon– [6/3/1405]. También raro es el fenómeno de un poema oficial, cortesano, judío despues de 1391. La atención de Juan Alfonso de Baena y de la reina Isabel al cortesano, científico, poeta Don Mosse y su obra puede inspirar contribuciones en dos campos. El primero sería el interés por poetas individuales en la obra colectiva Cancionero de Baena (CB). El segundo concierne a la cultura y literatura romance de las comunidades Hispano-Judías –especialmente su mileu cortesano y científico– de la baja edad media. Se arguye que el poema refleja la biografía, período y contexto familiar del poeta. Su compromiso con las ciencias y la poesía no se ocullta en el texto. Como en otros casos de la época, no hay contradicción. En su caso la distancia se entiende mejor prestando atención a la dinastía Ibn Zarzal, su entorno y su preocupación por la retórica, particularmente la epideíctica.
Mercaderes y judíos nazaríes. Una mirada al mundo de los negocios a finales de la Edad Media.
Authors: Fábregas Garcia Adela
Published: January 2020

Se aborda la caracterización de las funciones comerciales que desarrollan los judíos nazaríes en sus contactos con comunidades mercantiles extranjeras activas en el reino. Esta primera aproximación a la cuestión se centra en el análisis de los datos contenidos en el libro de contabilidad de uno de esos mercaderes, el genovés Agostino Spinola, que actuaría preferentemente en la costa granadina, con centro en la localidad de Almuñécar, hasta 1442. Allí establecería contactos con representantes de la comunidad judía residente en la localidad.
HUBUNGAN ANTARA DUKUNGAN SOSIAL KELUARGA DENGAN PSYCHOLOGICAL WELL-BEING PADA PEKERJA SEKS KOMERSIAL DI PANTI REHABILITASI
Authors: Hailitik Welhelmina Maria yuniaputry , Setianingrum Maggareta Erna
Published: January 2020

Abstract

The research aims to knowing the relationship between social support and psychological well-being in commercial sex worker. This research is designed by using sampling saturated technique with 55 participants. Variable of family social support using Cutrona's theory (1987) which consists of 24 items and psychological well-being variable using Ryff's theory (1989) which consists of 42 items. The research method in data collection using the scale method, that is the scale of family social support and the ryff’s psychological well-being scale. Data analysis using the product moment correlation analysis techniques and obtained a comparison coefficient of 0.290 with a sig value. = 0,000 (p <0.001). Based on the research results shows a positive relationship between family social support and psychological well-being on commercial workers in rehabilitation home.

 

Keywords: Family Social Support, Psychological well-being, Commercial Sex Worker.
Effect of incubation with lipopolysaccharide and interferon-γ on reactive astrogliosis
Authors: Hua Xiaoli , Wang Yi , Yang Chunbo , Chai Ruifeng , Li Xiang , Tayier Gulifeire , Pan Pengfei , Yu Xiangyou
Published: January 2020

Sepsis associated encephalopathy is a common complication of sepsis, but its pathogenesis of sepsis-associated encephalopathy remains unclear. Astrocytes are the most abundant brain glial cells, and reactive astrogliosis, a pathological response to central nervous system diseases, has a clear disease and disease-stage specificity. Functional changes of astrocytes are of great significance for the detection and prognosis of sepsis-associated encephalopathy. The pathogenesis of sepsis-associated encephalopathy was explored at the cellular level by examining astrogliosis in an in vitro model of sepsis-associated encephalopathy. Astrocytes of Wistar neonatal rats were incubated with different concentrations of lipopolysaccharide combined with interferon-γ. Cell viability was assessed by levels of tumor necrosis factor-α, interleukin-6, nitric oxide, reactive oxygen species, glial fibrillary acidic protein, changes of astrocyte morphology, and prevalence of apoptosis and necrosis. Compared with the control group, the cell viability of treated groups was decreased. The levels of tumor necrosis factor-α, interleukin-6, nitric oxide, reactive oxygen species, and glial fibrillary acidic protein were increased, hypertrophy of astrocytes was observed, and apoptosis was increased. The pathogenic outcomes of astrogliosis in sepsis-associated encephalopathy is discussed and a new tool provided to explore the pathogenesis of sepsis-associated encephalopathy at the cellular level.
Contrasting effects of acute and long-term corticosterone treatment on amyloid-β, beta-secretase 1 expression, and nuclear factor kappa B nuclear translocation
Authors: Hou Yangyang , Luo Shaolei , Zhang Yaping , Jia Yue , Li Haoran , Xiao Chunjie , Bao Hongkun , Du Jing
Published: January 2020

Regulation of neuroinflammation is critical to control the detrimental impact of chronic stress in the central nervous system. Neuroinflammation occurs in response to chronic stress, leading to enhanced neuronal damage in the brain. We investigated the regulatory effects of stress hormone corticosterone on neuroinflammation regulator, as well as amyloid-β and Beta-secretase 1related signaling. We demonstrate that corticosterone can both positively and negatively regulate amyloid-β expression, which may be related to the ratio of neuroinflammation regulator and Beta-secretase 1 signaling in rat primary cortical neurons. Thirty minutes of treatment with 1μM corticosterone significantly decreased the nuclear translocation of neuroinflammation mediator neuroinflammation regulator (Western Blot: P < 0.05, Immunofluorescence: P < 0.001) and production of Beta-secretase 1 enzyme (P < 0.01), which was accompanied by a reduction in amyloid-β1-42 levels (P < 0.01). In contrast, 1 µM corticosterone treatment over 3 days increased nuclear neuroinflammation regulator localization (P < 0.001), followed by the upregulation of Beta-secretase 1 (P < 0.01) and amyloid-β1-42 (P < 0.05) expression. This work is the first to demonstrate that the duration of corticosterone exposure can promote or inhibit amyloid-β production, and to link this effect with Beta-secretase 1 / neuroinflammation regulator signaling, together with providing valuable insight into the mechanisms of neuroinflammation and neuroprotection.
Diphenyleneiodonium chloride synergizes with diazoxide to enhance protection against amyloid β induced neurotoxicity
Authors: Fu Qingxi , Gao Naiyong , Che Fengyuan , Xu Guangyin , Han Hongxing , Su Quanping , Ma Guozhao
Published: January 2020

We examined synergistic effects of inhibiting reactive oxygen species generated from the mitochondria and from nicotinamide adenine dinucleotide phosphate oxidase on neurotoxicity. Primary hippocampal neurons were exposed to amyloid β, and the cells were treated with diazoxide or/and diphenyleneiodonium chloride. We found that the cell viability was decreased significantly after exposure to amyloid β for 72 h with higer reactive oxygen species and malondialdehyde levels, higher caspase-3 and cleaved caspase-3 levels and lower B-cell lymphoma 2 (Bcl-2) level. Both diazoxide and diphenyleneiodonium increased cell viability by inhibiting the increase in reactive oxygen species and caspase-3 activity as well as the decrease in Bcl-2 induced by amyloid β. The combination of diazoxide and diphenyleneiodonium exhibited better protective effects compared to a single treatment. In conclusion, the activation of a mitochondrial potassium channel in combination with the inhibitor of nicotinamide adenine dinucleotide phosphate oxidase exhibit synergistic protective effects against amyloid β neurotoxicity.
Migraine-linked characteristics of transcranial magnetic stimulation-induced phosphenes
Authors: Ekkert Aleksandra , Noreikaitė Karolina , Valiulis Vladas , Ryliškienė Kristina
Published: January 2020

Transcranial magnetic stimulation is used to explore visual cortex hyperexcitability in migraine. We hypothesized that the phosphene threshold in subjects suffering from migraines with and without aura would be lower than in controls, and this phenomenon could be linked to higher pain and disability levels. We also implied that subjects with lower phosphene threshold could see more phosphenes of different colors and shapes. Our primary objective was to compare the phosphene threshold between migraine without aura, migraine with aura, and control groups and investigate which factors contribute to different phosphene parameters in migraineurs. Secondary objectives were to compare color, shape, and number of phosphenes between groups and assess pain and disability level correlation with the phosphene characteristics. Phosphene threshold in migraine without aura, migraine with aura, and control groups were 68±9.5% vs. 75±12%, vs. 80±11%, respectively. Other phosphene parameters (number, color and shape) did not differ between groups. Average pain level during the attack did not correlate with phosphene threshold significantly, though the non-significant trend for negative correlation of migraine disability assessment scale score and a phosphene threshold has been found the higher was migraine disability assessment scale value, the lower was phosphene threshold (β = ‒0.255; P = 0.139). Other variables: gender, age, migraine subtype, migraine duration and use of hormone contraceptives - were not related to the phosphene threshold value. Our study provides additional data on visual cortex hyperexcitability in migraineurs, regarding transcranial magnetic stimulation with a figure-of-eight coil. Visual cortex excitability might be linked to higher disability.
Application of injectable hydrogels for cardiac stem cell therapy and tissue engineering
Authors: Narayan Alagarsamy Keshav , Yan Weiang , Srivastava Abhay , Desiderio Vincenzo , Dhingra Sanjiv
Published: January 2020

Cardiovascular diseases are responsible for approximately one-third of deaths around the world. Among cardiovascular diseases, the largest single cause of death is ischemic heart disease. Ischemic heart disease typically manifests as progressive constriction of the coronary arteries, which obstructs blood flow to the heart and can ultimately lead to myocardial infarction. This adversely affects the structure and function of the heart. Conventional treatments lack the ability to treat the myocardium lost during an acute myocardial infarction. Stem cell therapy offers an excellent solution for myocardial regeneration. Stem cell sources such as adult stem cells, embryonic and induced pluripotent stem cells have been the focal point of research in cardiac tissue engineering. However, cell survival and engraftment post-transplantation are major limitations that must be addressed prior to widespread use of this technology. Recently, biomaterials have been introduced as 3D vehicles to facilitate stem cell transplantation into infarct sites. This has shown significant promise with improved cell survival after transplantation. In this review, we discuss the various injectable hydrogels that have been tried in cardiac tissue engineering. Exploring and optimizing these cell-material interactions will guide cardiac tissue engineering towards developing stem cell based functional 3D constructs for cardiac regeneration.
Factors IX, XI, and XII: Potential Therapeutic Targets for Anticoagulant Therapy in Atherothrombosis
Authors: Rai Vikrant , Balters Marcus W. , Agrawal Devendra K.
Published: January 2020

Atherosclerosis is a leading cause of cardiovascular and neurological ischemic events. Plaque rupture leads to the exposure of highly thrombogenic material with blood and results in the activation of the coagulation cascade, thrombus formation, and embolic events. Although antiplatelets and anticoagulants are used to prevent thromboembolic episodes, bleeding episodes remain the major adverse effect. Decreased ischemic events have been reported while comparing oral rivaroxaban and apixaban with aspirin to improve the therapeutic outcome in several clinical trials, including Anti-Xa Therapy to Lower Cardiovascular Events in Addition to Standard Therapy in Subjects with Acute Coronary Syndrome-Thrombolysis in Myocardial Infarction 51, Apixaban for Prevention of Acute Ischemic and Safety Events, and GEMINI-ACS-1 phase II clinical trials. However, there were bleeding episodes. Thus, there is an unmet need for better therapeutic strategies. Therefore, the current focus is to target Factors IX, XI, and XII to develop safer and efficient strategies. In this article, we critically reviewed and discussed the limitations of current therapies and the potential of targeting Factors IX, XI, and XII for anticoagulant therapy in atherothrombosis.
Alterations in Doppler-derived renal venous stasis index during decompensation of right heart failure and fluid overload in a patient with pulmonary hypertension
Authors: Husain-Syed Faeq , Birk Horst-Walter , Tello Khodr , Richter Manuel J. , Ronco Claudio , McCullough Peter A. , Schörmann Tanja , Ferrari Fiorenza , Yücel Gökhan , Yazdani Babak , Walmrath Hans-Dieter , Seeger Werner , Gall Henning , Ghofrani H. Ardeschir
Published: January 2020

Renal congestion is becoming recognized as a potential contributor to cardiorenal syndromes. Adequate control of congestion with simultaneous preservation of renal function has been proposed as a central goal of the management of heart failure. We report our care of a 48-year-old woman suffering from right heart failure and massive fluid overload due to severe pulmonary hypertension secondary to a combination of left-heart disease and status after recurrent pulmonary embolisms. Alterations in Doppler-derived intrarenal venous flow patterns and a novel renal venous stasis index were used to evaluate improvement in renal venous congestion during decompensation. Due to refractory congestion despite optimal medical treatment and continuous veno-venous hemodialysis, a peritoneal dialysis catheter was placed to relieve the massive ascites. The paracentesis of ascites led to a significant loss of weight, normalization of hydration status with subsequent termination of continuous veno-venous hemodialysis, and a significant improvement in clinical and echocardiographic parameters. Renal Doppler ultrasonography showed continuous improvement in intrarenal venous flow patterns and the renal venous stasis index indicative of effective decongestion up to a normal intrarenal venous flow pattern and renal venous stasis index. Furthermore, residual renal function increased during follow-up. This case demonstrates the feasibility of renal Doppler ultrasonography as a simple, non-invasive, and integrative measure of renal congestion. The renal venous stasis index and intrarenal venous flow patterns may be useful to evaluate the treatment response and to guide therapy in patients with right heart failure.
Evaluation of acute chest pain: Evolving paradigm of coronary risk scores and imaging
Authors: Alderwish Edris , Schultz Emily , Kassam Zain , Poon Michael , Coplan Neil
Published: January 2020

There is a broad differential diagnosis for patients presenting with acute chest pain. History, physical examination, electrocardiogram, and serial troponin assays are pivotal in assessing patients with suspected acute coronary syndrome. However, if the initial workup is equivocal, physicians are faced with a challenge to find the optimal strategy for further triage. Risk stratification scores have been validated for patients with known acute coronary syndrome, such as the TIMI and GRACE scores, but there may be limitations in undifferentiated chest pain patients. Advancements in imaging modalities such as coronary computed tomography angiography and the addition CT derived fractional flow reserve, have demonstrated utility in evaluating patients presenting with acute chest pain. With this article, we aim to provide a comprehensive review of the non-invasive modalities that are available to evaluate acute chest pain patients suspected of cardiac etiology in the emergency room. We also added a focus on new imaging modalities that have shown to have prognostic implications in stable ischemic heart disease.
Theological-Psychological Interpretation (Refl ection) of the Phenomenon of Refl ection
Authors: Sedankina T. E.
Published: January 2020

In contemporary theological teachings there is no rational definition of the term and description of the methodology of religious reflection, due to the ambiguity of different empirical descriptions of this phenomenon in different religions and within one religion. In this study, the emphasis is placed not on the statement of reflection, as it is empirically described in various religious traditions, but on the analysis of one’s inner experiences, analysis and synthesis of one’s self-reflection. Analysis, synthesis and comparison of the Hegelian concept of the reflection of the spirit and the teachings of Ibn Arabi on immersion in the depths of himself through intuitive contemplation.

In the course of religious reflection, consisting of self-knowledge, self-observation and introspection, the evidence base of a person’s faith is assembled “in harmonious mosaic”, and in the process of finding out one’s own path to faith, the reflecting one begins to see the source and the tools that influence the course of faith. As a result of theological understanding of the phenomenon of reflection, it was revealed that if ordinary psychological reflection is knowing oneself through the eyes of another, moreover knowing “oneself externally”, then religious reflection is knowing “oneself internally” through the eyes of “oneself externally”. This process requires a deep inner work, based on religious-psychological and at the same time rational methodology. The synthesis of these two methodologies is proposed by the author of the article on the basis of correlation of the doctrine of self-knowledge of Sheikh Ibn Arabi and the reflection of the spirit of G. V. F. Hegel.

The author declares that there is no conflict of interest.
Institutions of the Muslim Community of the Simbirsk – Ulyanovsk Volga Region During the 1920–1930s
Authors: Kobzev A. V.
Published: January 2020

The article discusses de-institutionalization of the Muslim community of the Simbirsk - Ulyanovsk Volga region in 1920-1930s. This process took place as a result of the antireligious policies of the Soviet state. A retrospective assessment of the pace and extent of deinstitutionalization is addressed in the article. Territorial and administrative changes, changes in the number of mosques, religious schools and representatives of the Muslim clergy from 1917 until the end of 1930s is analyzed. The article is written on the basis of office documents from the State Archive of the Ulyanovsk Region and the State Archive of Recent History of the Ulyanovsk Region. The author concludes that the de-institutionalization of the Muslim community in the Simbirsk – Ulyanovsk Volga region was asynchronous. Muslim schools ceased their activities in the beginning of 1930s. More than half of mosques in the region were closed by the early 1940s. Muslim clergy was subjected to various forms of socio-legal discrimination, and in the post-war period only a few were able to resume professional religious activities.

The author declares that there is no conflict of interest.
ANALYSIS OF EFFICIENCY AND BREAK EVEN POINT OF SAWMILL WOOD INDUSTRY : CASE STUDY AT UD. TIMBER JAYA MAKMUR SUKARAJA, SELUMA, BENGKULU
Authors: Julirin Muhammad , Hasanuddin Hasanuddin , Koto Hidayat
Published: January 2020

Sengon wood sawmill UD. Timber Jaya Makmur in Sukaraja produces Super Grade sengon beam. Its side products are All Grade sengon beam, irregular sengon narrow board and sawdust. Sengon wood, in addition to be a wooden beam, commonly is also used as materials for lighters, pencils, buildings or furniture, plywood, particle boards and paper. In Bengkulu province, there were 127 small and medium scale sawmill industries in 2016; two of them were in Seluma district. This research aimed to evaluate the economical efficiency and determine its break even point (BEP) of UD. Timber Jaya Makmur Sukaraja, Seluma, Bengkulu. The data collected were the daily wooden beam and its side products produced during 2016-2017. Analysis was conducted to  calcule RC ratio, BEP-units and BEP-sales. Results of the research showed that UD. Timber Jaya Makmur Sukaraja, Seluma, Bengkulu was efficient (RC ratio = 1.08), its products exceeded the BEP at May 2017, December 2016, April 2017 and September 2017; but its lower that BEP at February, October, June, January and March 2017. Overall UD. Timber Jaya Makmur gets its BEP-unit of 412.4731 m3  or its BEP-sale of  Rp. 474,344,061.Industri gergajian (sawmill) kayu sengon UD. Timber Jaya Makmur Seluma memproduksi balken Super Grade serta hasil sampingnya yakni balken All Grade, sebetan kayu dan serbuk gergaji. Pohon kayu sengon, selain untuk balken, juga biasa dimanfaatkan sebagai bahan korek api, pensil, bangunan atau mebeler, kayu lapis, papan partikel dan kertas. Di propinsi Bengkulu, industri pengergajian kayu sebanyak 127 perusahaan atau industri skala kecil dan menengah pada tahun 2016. Khusus, kabupaten Seluma hanya ada dua industri pengergajian kayu. Penelitian ini dilakukan pada oktober 2017 bertujuan untuk menentukan nilai efisiensi dan titik impas atau break even point (BEP) pada UD. Timber Jaya Makmur Seluma. Data yang dikumpulkan dihitung dengan R-C ratio, BEP-unit dalam m3 dan BEP-penjualan dalam rupiah.Setelah dianalisis efisiensi usaha atau industrinya, didapat nilai R-C ratio yaitu 1,08 dan dihitung BEP-unit (m3) maupun BEP-penjualan (Rp), didapat beberapa bulan yang melewati nilai titik impas (BEP)  yakni Mei 2017, Desember 2016, April 2017 dan September 2017. Sebaliknya, Februari, Oktober, Juni, Januari dan Maret 2017 tidak melewati nilai BEP. Secara keseluruhan UD. Timber Jaya Makmur mendapat nilai titik impas (BEP) yaitu BEP-unit sebesar 412,4731 m3 dan BEP-penjualan sebesar Rp. 474.344.061.
Alternative Organic Liquid Fertilizer from Meatball Water Decoction with Banana Humps Activator
Authors: Cahyani S. D. , Amalia N. R. , Achmad A. H. , Hilmi M. , Triasih D.
Published: January 2020

This study aimed to determine the effect of the use of EM4 and Local Microorganism (LM) activators from banana hump (Kepok banana, Raja banana, and Ambon banana) on the manufacture of organic liquid fertilizer derived from waste meatball water stew. The research method used in this study was Completely Randomized Design (CRD) consisting of 4 treatments and three replications, namely: P1 EM4, P2 (Local Microorganism from Kepok banana hump ), P2 (Local Microorganism from Ambon banana hump), P3 (Local Microorganism from Raja banana hump). In this study testing the levels of Nitrogen, Phosphorus, Potassium, Carbon, and pH levels in organic liquid fertilizer from boiled meatball water. The data obtained from this study were analyzed using Complete Randomized Design and Duncan's advanced test. The results of the addition of EM4 activator and banana hump MOL on the manufacture of organic liquid fertilizer from meatball decoction water showed no significant effect (P> 0.05) on N, K, and pH levels on fertilizers. The results showed a significant effect (P <0.05) on the P content of fertilizer. The highest C content was found in P2, while the highest C / N ratio was found in P0.
PENGEMBANGAN STRATEGI MULTIPLE INTELLIGENCES PADA PEMBELAJARAN BERNEGOSIASI SISWA KELAS XI SMK MUHAMMADIYAH 1 PASURUAN
Authors: Rosidah Ilmiyatur
Published: January 2020

Tujuan penelitian ini adalah mengembangkan strategipembelajaran, pada pembelajaran bernegosiasi siswa kelas XI SMKMuhammadiyah 1 Pasuruan, yang diharapkan dapat meningkatkankemampuan siswa dalam bernegosiasi. Pengembangan strategi inimenggunakan pengembangan yang diadaptasi dari model pengembanganDick &Carey (1990). Strategi ini dikembangkan dari analisis kebutuhanpeserta, guru, dan karakteristik peserta didik dengan teknik angket,observasi, tes, dan dokumentasi. Setelah melakukan analisis kebutuhanlangkah selanjutnya adalah merumuskan tujuan, analisis pembelajaran,kemudian mengembangkan rancangan strategi pembelajaran. Langkahselanjutnya adalah melakukan uji validitas ahli dan melkukan revisi,kemudian uji coba pada kelas. Strategi yang dikembangkan padapenelitian ini adalah strategi multiple intelligences. Hasil penggumpulandata menunjukkan sebagai berikut. Analisis kebutuhan siswamenunjukkan: dibutuhkan strategi pembelajaran baru yang lebihmemotivasi dan mengaktifkan peserta didik, materi negosiasi perlumendapat penjelasan lebih rinci agar peserta didik mendapat pemahamankonsep lebih baik dan benar, sehingga peserta didik mampu bernegosiasidengan baik. Peserta didik secara umum mengalami kesulitan belajarbernegosiasi, apalagi dengan peserta didik dengan gaya belajaraudiovisual. Karena peserta didik dengan tipe ini sangat sulit untukberinteraksi/ berbicara depan umum, kekurangan peserta didik dalambelajar bernegosiasi adalah trik atau cara mudah untuk benegosiasi.Produk yang dihasilkan pada penelitian ini berupa model pembelajarandengan strategi multiple intelligencesyang dikembangkan pada rencanapelaksanaan pembelajaran danhandout.
RNA helicase DDX52 is produced in significantly higher quantities in the tumors of males with DIPG.
Authors: Mamoor Shahan
Published: January 2020

Diffuse intrinsic pontine glioma (DIPG) is a pediatric cancer with the worst prognosis of any cancer known to man. 99% of patients will expire within 5 years (1). The poor outcomes in this disease demand a basic understanding of the transcriptional behavior of DIPG tumors, how they differ from the tissue of origin and how they differ between patients. We compared the transcriptomes of tumors from men and women diagnosed with the disease using a published dataset (2) to more thoroughly understand sex-specific transcriptional differences in cancer and found that RNA helicase DDX52 (3) was among the genes most differentially expressed based on the sex of the patient. DDX52 is not located on a sex chromosome. Multiple DDX genes have been found to be dysregulated in a variety of cancers (4-16); this is the first report of dysregulation of a DDX gene in males with diffuse intrinsic pontine glioma.
PENGGUNAAN SMART PHONE SEBAGAI MEDIA KOMUNIKASI DALAM MEMBERIKAN INFORMASI KEPADA BAWAHAN
Authors: Mawaddah Armi
Published: January 2020

Teknologi adalah keseluruhan sarana untuk menyediakan barang-barang yang diperlukan bagi kelangsungan dan kenyamanan hidup manusia. Sebuah perusahaan dibutuhkan suatu pola komunikasi yang dapat menjaga hubungan antara pihak eksternal maupun internal dari perusahaan tersebut, baik perusahaan yang bersifat formal maupun informal. Smartphone sangat sering digunakan sebagai media komunikasi dalam memberikan informasi seperti surat edaran, perubahan system aturan yang ada di rumah sakit melalui aplikasi whatsapp. Tujuan dari kajian ini adalah untuk mengetahui pengaruh dan manfaat smartphone sebagai media komunikasi kepada bawahan yaitu ketua tim dan perawat pelaksana. Metode yang digunakan dalam kajian ini diambil dari berbagai jurnal penelitian yang telah di akui. Penulis mengambil kurang lebih 14 jurnal. Hasil fungsi komunikasi dalam organisasi melalui group chat whatsapp oriflamme yaitu Hasil penelitian ini menunjukkan bahwa fungsi komunikasi dalam organisasi melalui group chat WhatsApp Oriflame terdiri dari 4 fungsi komunikasi, yaitu: fungsi informatif, fungsi regulatif, fungsi persuasif dan fungsi integrative. bahwa komunikasi organisasi yang dilakukan oleh pegawai sangat dibantu oleh aplikasi WhatsApp. Aplikasi WhatsApp memiliki peran penting dalam mendukung fungsi komunikasi organisasi yang meliputi fungsi produksi dan pengaturan, fungsi pembaharuan, fungsi pemeliharaan, fungsi tugas, fungsi perintah, dan fungsi relasional. Rekomendasi diharapkan pengguna smartphone lebih tahu dan dapat memanfaatkan smart phone lebih baik.
Confounds in “failed” replications
Authors: Bressan Paola
Published: January 2020

Reproducibility is essential to science, yet a distressingly large number of research findings do not seem to replicate. Here I discuss one underappreciated reason for this state of affairs. I make my case by noting that, due to artifacts, several of the replication failures of the vastly advertised "Open Science Collaboration’s Reproducibility Project: Psychology" turned out to be invalid. Although these artifacts would have been obvious on perusal of the data, such perusal was deemed undesirable because of its post hoc nature and was left out. However, while data do not lie, unforeseen confounds can render them unable to speak to the question of interest. I look further into one unusual case in which a major artifact could be removed statistically—the nonreplication of the effect of fertility on partnered women’s preference for single over attached men. I show that the “failed replication” datasets contain a gross bias in stimulus allocation which is absent in the original dataset; controlling for it replicates the original study’s main finding. I conclude that, before being used to make a scientific point, all data should undergo a minimal quality control—a provision, it appears, not always required of those collected for purpose of replication. Because unexpected confounds and biases can be laid bare only after the fact, we must get over our understandable reluctance to engage in anything post hoc. The reproach attached to p-hacking cannot exempt us from the obligation to (openly) take a good look at our data.
PROSEDUR PENGAWASAN PEMBIAYAAN MURABAHAH PADA PT. BANK BRISYARIAH KANTOR CABANG PEMBANTU (KCP) BOGOR PAJAJARAN
Authors: Puspitasari Ratih
Published: January 2020

Bank Syari’ah merupakan badan usaha yang tugasnya menghimpun dana dari nasabah dan menyalurkan kembali kepada nasabah dalam bentuk pembiayaan maupun jasa perbankan. Prosedur pembiayaan adalah gambaran sifat atau metode untuk melaksanakan kegiatan pembiayaan. Seseorang yang berhubungan dengan pembiayaan harus menempuh prosedur pembiayaan yang sehat. Berbicara mengenai pembiayaan tidak terlepas dari fungsi dan aktifitas Bank Syari’ah karena meskipun terdapat bermacam produk yang ditawarkan Bank Syari’ah, pembiayaan masih merupakan prioritas kegiatan operasional. Dalam pemberian pembiayaan terdapat beberapa unsur risiko. Penyelewengan mudah timbul sejak pembiayaan itu disalurkan oleh bank kepada nasabah sampai dengan pembiayaan itu dibayar lunas oleh nasabah. Oleh karena itu pengawasan pembiayaan harus diberikan sampai dengan pembiayaan dibayar lunas oleh nasabah. Untuk itu, penulis memilih tentang prosedur pengawasan pembiayaan murabahah sebagai tugas akhir untuk menjawab rumusan masalah “ Apa saja produk pembiayaan murabahah pada PT. Bank BRISyariah Kantor Cabang Pembantu (KCP) Bogor Pajajaran, bagaimana prosedur pengawasan pembiayaan murabahah pada PT. Bank BRISyariah Kantor Cabang Pembantu (KCP) Bogor Pajajaran, bagaimana pembiayaan bermasalah dan penyelesaian pembiayaan bermasalah pada PT. Bank BRISyariah Kantor Cabang Pembantu (KCP) Bogor Pajajaran”.
supervisi pendidikan 1
Authors: deswita Linda
Published: January 2020

manage and regulate. Scientific articles should be prepared using systematic methods and steps to make it easy to conduct and carry out research. This article researchers used the literature study method by collecting literature (material materials) taken from book sources, journals, and other sources related to the science of Educational Administration. The method of literature relating to topics of interest can help make it easier to formulate research problems.
OPTIMALISASI PEMBANGUNAN ZONA INTEGRITAS MENUJU WILAYAH BEBAS KORUPSI (WBK) DAN WILAYAH BIROKRASI BERSIH MELAYANI (WBBM) PADA LEMBAGA PELAYANAN PERTANAHAN
Authors: Nugroho Romi
Published: January 2020

Pembangunan Zona Integritas dalam mewujudkan organisasi yang memiliki komitmen besar untuk memberikan pelayanan pertanahan secara bersih perlu dicanangkan sejak dini. Kementerian Agraria dan Tata Ruang/Badan Pertanahan Nasional yang mempunyai kewenangan pada pelayanan pertanahan telah mencanangkan pembangunan Zona Integritas Menuju Wilayah Bebas Korupsi (WBK) dan Wilayah Birokrasi Bersih Melayani (WBBM) dengan akan mengusulkan unit kerja yang memiliki kriteria sesuai Peraturan Menteri Pendayagunaan Aparatur Negara dan Reformasi Birokrasi Nomor 52 Tahun 2015. Kajian yang menggunakan pendekatan deskriptif-kualitatif dengan menjabarkan tindak lanjut dari pencanangan pembangunan Zona Integritas memberikan penjelasan bahwa potensi diusulkannya unit kerja (Kantor Pertanahan) berada pada kantor dengan kualitas pelayanan baik dan memiliki komitmen menghadirkan pelayanan prima berdasarkan hasil penilaian tim, meskipun dalam kenyataan jumlahnya tidak banyak. Adapun sebelum benar-benar dinilai oleh tim, dapat didahului dengan uji coba pengisian Lembar Kerja Evaluasi (LKE) guna mengukur kelebihan dan kekurangan, sehingga dapat segera dievaluasi.
KONSEP DAN PRINSIP PENILAIAN PKN SD/MI
Authors: Inin Fitria
Published: January 2020

Penilaian adalah pemeriksaan secara terus-menerus untuk mendapatkan informasi yang meliputi siswa, guru, program pendidikan dan proses belajar mengajar untuk mengetahui tingkat perubahan siswa dan ketepatan keputusan tentang gambaran siswa dan efektivitas program. Pengukuran adalah suatu proses yang menghasilkan gambaran berupa angka-angka hasil pengamatan mengenai beberapa ciri tentang suatu objek, orang atau peristiwa. Sedangkan Penilaian pada hakikatnya merupakan suatu proses membuat keputusan tentang nilai suatu objek. Secara prinsip, penilaian dalam PKn tidak berbeda dengan penilaian lainnya, hanya yang berbeda penekanannya , yaitu pada aspek afektif.Kaitannya denga proses pembelajaran, penilaian yang dilakukan gurubertujuan
Difference score reliabilities within the RIAS-2 and WISC-V
Authors: Farmer Ryan L. , Kim Samuel Y.
Published: January 2020

Many prominent intelligence tests (e.g., WISC-V & RIAS-2) offer methods for computing subtest- and composite-level difference scores. This current study uses data provided in the technical manual of the Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) and Reynolds Intellectual Abilities Scale, Second Edition (RIAS-2) to calculate reliability coefficients for difference scores. Subtest-level difference score reliabilities range from 0.59 to 0.99 for the RIAS-2 and from 0.53 to 0.87 for the WISC-V. Composite-level difference score reliabilities generally range from 0.23 to 0.95 for the RIAS-2 and from 0.36 to 0.87 for the WISC-V. Emphasis is placed on comparisons recommended by test publishers and a discussion of minimum requirements for interpretation of differences scores is provided.