bluuebunny/crossref_metadata_2025 huggingface dataset:
Rehabilitation for patients with rheumatic diseases: Patient experiences of a structured goal planning and tailored follow-up programme
Authors: Dager Turid Nygaard , Kjeken Ingvild , Berdal Gunnhild , Sand-Svartrud Anne-Lene , Bø Ingvild , Dingsør Anne , Eppeland Siv Grødal , Hagfors Jon , Hamnes Bente , Nielsen Merete , Slungaard Bente , Wigers Sigrid Hørven , Hauge Mona-Iren
Published: November 2017

Objective:

To explore the significance of the content of rehabilitation in terms of achieving a personal outcome, and to understand the significance of tailored follow-up interventions for individual efforts to prolong health behaviour change after rehabilitation.

Design:

Semi-structured interviews with patients who had received an extended rehabilitation programme. All interviews were transcribed verbatim. A thematic analysis was applied.

Subjects:

A purposeful sample of 18 patients with rheumatic diseases who had attended specialized multidisciplinary rehabilitation with an extended programme consisting of a self-help booklet, structured goal-setting talks and tailored follow-up calls based on motivational interviewing.

Results:

Four overarching and interrelated themes were identified. Experienced Person-centred interventions represented a basis for the patients’ motivation and personal outcomes. Confident self-management describes a new confident approach to exercise and illness management after rehabilitation with person-centred interventions. For many, this included reaching a different mindset, a change of illness perception. Continuity of the personal outcomes describes the importance of follow-up telephone calls to maintain the focus on goals and continued efforts. Building on established relationships and practising person-centred communication were essential.

Conclusion:

Tailoring of communication and rehabilitation interventions may be a premise for enhancing health behaviour, including a beneficial illness perception. Structured goal setting and follow-up telephone calls using motivational interviewing enhance motivation and may contribute to prolonged goal attainment.
Pancreatic function following post‐endoscopic retrograde cholangiopancreatography pancreatitis: A controlled cohort study with long‐term follow‐up
Authors: Leerhøy Bonna , Shabanzadeh Daniel M , Nordholm-Carstensen Andreas , Novovic Srdan , Hansen Mark B , Jørgensen Lars N
Published: November 2017

Background

Acute pancreatitis is one of the most common causes of gastrointestinal‐related hospitalization and the incidence is increasing. Endo‐ and exocrine pancreatic function can be compromised after acute pancreatitis.

Objective

The purpose of this study was to explore the long‐term consequences of post‐endoscopic retrograde cholangiopancreatography pancreatitis (PEP) on pancreatic function.

Methods

A follow‐up study was carried out with prospective assessment of endo‐ and exocrine pancreatic function among cases with previous PEP and matched controls from a Danish cohort consisting of 772 patients undergoing first‐time ERCP. Pancreatic function was evaluated by faecal‐elastase‐1 test, blood levels of haemoglobin A1c, C‐peptide, vitamin B12, vitamin D and indirectly by changes in body weight.

Results

Twenty‐nine cases and 49 controls participated in the study. Mean follow‐up time (standard deviation) was 58 (21) months. Twelve (41%), eight (28%) and nine (31%) patients had mild, moderate and severe PEP, respectively. There was no difference between cases and controls with regard to pancreatic function parameters and PEP severity was not associated with pancreatic function. Factors associated with pancreatic function impairment included body mass index, alcohol consumption, age and smoking.

Conclusion

This study suggests that long‐term pancreatic function following PEP is similar to the pancreatic function of other patients with comparable gallstone‐related morbidity.
Terrorism before and after 9/11 – a more dangerous world?
Authors: Smith Meagan , Zeigler Sean M.
Published: November 2017

Was 9/11 the opening salvo in a new age of terrorism? Some argue that this act ushered in a more chaotic world. Others contend an increased focus on terrorism in the past 15 years is the result of conflating terrorist activity with insurgency. We shed light on these claims by analyzing data on domestic and transnational terrorist incidence from 1989 to 2014. The evidence suggests that the years since 9/11 have been different from those preceding them. Once the prevalence of conflicts is accounted for, the post-9/11 era is a significantly less terror prone period than the years before it. A country not suffering civil conflict was upwards of 60 percent more likely to experience terrorism prior to or during the year 2001 than since. However, the opposite trend holds for those countries with a higher proportion of Muslims. Prior to 2001, countries with higher Muslim populations experienced less domestic terrorism. Since 9/11, these countries have experienced significantly more terrorism – both domestic and international – than they had previously.
Digital health evaluation workshop for interprofessional healthcare students
Authors: Aungst Timothy Dy , Lahoz Monina R , Evans Paula J
Published: November 2017

The use of online resources by patients for their daily health needs has escalated with the proliferation of mobile devices and mobile apps. While healthcare professionals can help their patients access quality online resources and tools, they may not have received the education and training to do this effectively. To meet this educational need, a daylong workshop was developed at a health sciences university that aimed to increase awareness of students in various health disciplines of mobile health-related apps and federally sponsored websites that provide patient-friendly medical information.
Brachytherapy in the adjuvant management of keloid scars: literature review
Authors: Goutos Ioannis , Ogawa Rei
Published: November 2017

[Formula: see text]

Introduction:

Radiation therapy is a well-recognised modality for the adjuvant treatment of keloid scars. It can be conventionally delivered as external beam using a large apparatus at a distance from the lesion or as brachytherapy with specialised equipment to enable the delivery of treatment in the immediate vicinity of the keloidal tissue.

Methods:

An English literature review was performed with keywords ‘brachytherapy’ and ‘keloid’ using the databases PubMed, Embase and Web of Science from their individual dates of inception until June 2017. Studies pertinent to the field are presented in a chronological manner to depict the evolution of different brachytherapy strategies over the last decades. We also discuss considerations relating to the risk of secondary carcinogenesis, which are relevant to shared decision-making in the clinical setting.

Discussion:

Low dose rate interstitial brachytherapy was first introduced in the English literature in 1976 and currently appears to have been superseded by more modern approaches, including high dose rate interstitial brachytherapy. This modality compares favourably to more traditional modes of radiotherapy in terms of recurrence as well as rates of symptomatic relief from keloidal symptoms. Superficial brachytherapy was introduced more recently in the relevant literature and appears to be associated with favourable therapeutic outcomes compared to external beam radiation therapy.

Conclusion:

Brachytherapy is a valid modality of radiotherapy for the adjuvant treatment of keloid scars, with high dose rate interstitial and surface regimens gaining in popularity over recent years. Further research needs to focus on randomised controlled trials to further establish the role of different radiotherapy modalities in keloid scar management.
Investigation of efficacy of treatment in spinal cord injury: Erythropoietin versus methylprednisolone
Authors: Ozkunt Okan , Sariyilmaz Kerim , Gemalmaz Halil Can , Gürgen Seren Gülsen , Yener Ulaş , Dikici Fatih
Published: November 2017

Background:

Investigation of the expression of platelet-derived growth factor (PDGF)-β and glial fibrillary acidic protein (GFAP) in rats with spinal cord injury as a marker of neurologic recovery between groups treated with erythropoietin (EPO) and methylprednisolone (MP).

Methods:

Thirty adult female rats were randomly divided into three even groups. A laminectomy was applied to thoracic ninth vertebra and contusion injury was induced by extradural application of an aneurysm clip. Group 1 rats received one-time intrathecal administration of normal saline, group 2 rats received MP, and group 3 rats received EPO. Motor neurological function was evaluated by the Basso, Beattie, and Bresnahan (BBB) locomotor rating scale. Thirty days after the surgery, T8–10 segments of the spinal cords were extracted and the immunohistochemical assay revealed the number of PDGF-β- and GFAP-positive cells.

Results:

Evaluation of the last control animal showed that BBB score in the EPO group showed an increase from 1 to 12 ( p < 0.05). The immunohistochemical assay revealed that the number of PDGF-β- and GFAP-positive cells was significantly higher in EPO group ( p = 0.000) when compared to MP and control groups. After studying the effect of PDGF-β expression on the locomotor function, we determined that PDGF-β expression and locomotor function after a spinal injury has a strong relationship ( p < 0.05).

Conclusion:

EPO seems to better increase the expression of PDGF-β, thus produce better results in locomotor functions when compared to MP.
Workplace Spirituality and Organizational Performance in Indian Context: Mediating Effect of Organizational Commitment, Work Motivation and Employee Engagement
Authors: Garg Naval
Published: November 2017

Prior research on workplace spirituality has mostly looked at the antecedents and consequences of the construct. The purpose of the present research is to investigate the mediating effect of employee commitment, employee engagement and work motivation in the relationship between workplace spirituality and organizational performance in Indian context. Using standardized self-report measures and structural equation modelling (SEM), present research finds that two facets of organizational commitment (namely, affective and normative), employee engagement and work motivation partially mediate the relationship. Implications of these findings for academic theory as well as HR managers are discussed.
Functional Outcomes After the Surgical Management of Isolated Anterolateral Leg Chronic Exertional Compartment Syndrome
Authors: Gatenby Grace , Haysom Samuel , Twaddle Bruce , Walsh Stewart
Published: November 2017

Background:

Failure rates of up to 20% have been reported after fasciotomy for chronic exertional compartment syndrome (CECS). There is some evidence that postoperative failure and complication rates are higher in the posterior compartments of the lower leg than the anterolateral compartments. Isolated compartment surgery may put patients at risk of requiring revision surgery because of the risk of developing posterior compartment disease.

Hypothesis:

Isolated anterolateral fasciotomy for CECS, in the absence of posterior compartment symptoms, produces satisfactory functional outcomes.

Study Design:

Case series; Level of evidence, 4.

Methods:

Between 2006 and 2012, patients who had positive intracompartment pressure-testing findings and who underwent isolated anterolateral fasciotomy release for CECS were given a self-administered questionnaire. The minimum follow-up was 3 years. The questionnaire addressed time to return to sport and ongoing symptoms. A visual analog scale was used to assess pain during exercise before and after surgery (score: 0, no pain; 10, worst pain imaginable); overall satisfaction with the procedure was assessed as well. Of 31 eligible patients, 20 patients (36 legs operated on) were assessed.

Results:

Postoperatively, 90% of participants returned to the same or higher level of sport. The mean pain score during exercise before surgery was 8.17, whereas it was 1.74 after surgery. The overall mean patient satisfaction score was 8.64. Only 1 leg (2.8%) went on to develop posterior compartment syndrome.

Conclusion:

Isolated anterolateral fasciotomy for CECS produced excellent functional outcomes. Our rate of recurrence was low compared with those found in the literature, and 90% of participants returned to their same or higher level of sport postoperatively.
Excluded from school: Autistic students’ experiences of school exclusion and subsequent re-integration into school
Authors: Brede Janina , Remington Anna , Kenny Lorcan , Warren Katy , Pellicano Elizabeth
Published: November 2017

Background and aims

All children have the right to receive an education and to be included in school. Yet young people on the autism spectrum, who are already vulnerable to poor health and social outcomes, are at increased risk of school exclusion. The current study sought to understand the key factors surrounding the school exclusion experiences of a group of autistic students with particularly complex needs, and their subsequent re-integration into education.

Method

We interviewed nine intellectually able students (eight male, one female; M age = 13.3 years), all with a diagnosis of autism and the majority with a history of demand avoidant behaviour. We also interviewed their parents and teaching staff about the students’ past and current school experiences. All students were currently being educated within an ‘Inclusive Learning Hub’, specially designed to re-integrate excluded, autistic students back into school, which was situated within a larger autism special school.

Results

Young people and their parents gave overwhelmingly negative accounts of the students’ previous school experiences. Children’s perceived unmet needs, as well as inappropriate approaches by previous school staff in dealing with children’s difficulties, were felt to cause decline in children’s mental health and behaviour and, ultimately, led to their exclusion from school. Four key factors for successful reintegration into school were identified, including (i) making substantial adjustments to the physical environment, (ii) promoting strong staff–student relationships, (iii) understanding students’ specific needs, and (iv) targeted efforts towards improving students’ wellbeing.

Conclusion

The culmination – and escalation – of challenges students experienced in the students’ previous placements could suggest that the educational journey to exclusion from school is an inevitable consequence for at least some autistic children, including those with particularly complex behaviour, as sampled here. Yet, our study encouragingly showed that this was not necessarily the case. All the young people we spoke to reported being happy, safe and secure in their current placement, and re-engaged with school life. Outstanding issues remain, however, with regard to children’s reportedly slow academic progress and difficulties generalising the positive behaviour shown in school across home and community contexts.

Implications

More remains to be done to ensure that autistic children and young people’s progress at school is also mirrored in other settings. Future research also needs to develop more preventative approaches to avoid exclusion from school, including efforts towards improving education professionals’ knowledge and awareness of autism, and effective ways of responding to these students’ needs.
Use of the Avegant Glyph Head-Mounted Virtual Retinal Projection Display to Perform Vitreoretinal Surgery
Authors: Korot Edward , Thanos Aristomenis , Todorich Bozho , Rao Prethy , Stem Maxwell S. , Williams George A.
Published: November 2017

Objective:

To evaluate the use of a novel retinal projection display in vitreoretinal surgery.

Methods:

The Avegant Glyph virtual retinal display, which uses a light-emitting diode and micromirror array to project directly onto the retinas of the user, was evaluated. This unit was modified for better operating room characteristics. It was evaluated by 6 surgeons performing mock vitreoretinal surgeries.

Results:

The majority reported high 3-dimensional (3-D) depth rendition, little hindrance to communication, and high confidence to perform procedures. Due to a small ocular size, surgeons conveyed that the Glyph provides a novel enhanced view for performing procedures benefiting from simultaneous intra- and extraocular visualization such as scleral depression. Safety analysis by performing fundus autofluorescence after 2 hours of Glyph operation did not reveal any gross qualitative change.

Conclusion:

Use of the Avegant Glyph to perform vitreoretinal surgery may provide ergonomic advantages, while its visualization and high 3-D stereoscopic depth rendition instill high surgeon confidence to safely perform procedures. We are performing further studies with objective data to validate the potential of this technology.
Pulmonary function deficits in newborn screened infants with cystic fibrosis managed with standard UK care are mild and transient
Authors: Davies Gwyneth , Stocks Janet , Thia Lena P. , Hoo Ah-Fong , Bush Andrew , Aurora Paul , Brennan Lucy , Lee Simon , Lum Sooky , Cottam Philippa , Miles Joanne , Chudleigh Jane , Kirkby Jane , Balfour-Lynn Ian M. , Carr Siobhán B. , Wallis Colin , Wyatt Hilary , Wade Angie
Published: November 2017

With the advent of novel designer molecules for cystic fibrosis (CF) treatment, there is huge need for early-life clinical trial outcomes, such as infant lung function (ILF). We investigated the degree and tracking of ILF abnormality during the first 2 years of life in CF newborn screened infants.

Forced expiratory volume in 0.5 s (FEV0.5), lung clearance index (LCI) and plethysmographic functional residual capacity were measured at ∼3 months, 1 year and 2 years in 62 infants with CF and 34 controls.

By 2 years there was no significant difference in FEV0.5z-score between CF and controls, whereas mean LCI z-score was 0.81 (95% CI 0.45–1.17) higher in CF. However, there was no significant association between LCI z-score at 2 years with either 3-month or 1-year results. Despite minimal average group changes in any ILF outcome during the second year of life, marked within-subject changes occurred. No child had abnormal LCI or FEV0.5on all test occasions, precluding the ability to identify “high-risk” infants in early life.

In conclusion, changes in lung function are mild and transient during the first 2 years of life in newborn screened infants with CF when managed according to a standardised UK treatment protocol. Their potential role in tracking disease to later childhood will be ascertained by ongoing follow-up.
Accurate laser scanner to camera calibration with application to range sensor evaluation
Authors: Fuersattel Peter , Plank Claus , Maier Andreas , Riess Christian
Published: November 2017

Multi-modal sensory data plays an important role in many computer vision and robotics tasks. One popular multi-modal pair is cameras and laser scanners. To overlay and jointly use the data from both modalities, it is necessary to calibrate the sensors, i.e., to obtain the spatial relation between the sensors.

Computing such a calibration is challenging as both sensors provide quite different data: cameras yield color or brightness information, laser scanners yield 3-D points. However, several laser scanners additionally provide reflectances, which turn out to make calibration to a camera well feasible. To this end, we first estimate a rough alignment of the coordinate systems of both modalities. Then, we use the laser scanner reflectances to compute a virtual image of the scene. Stereo calibration on the virtual image and the camera image are then used to compute a refined, high-accuracy calibration.

It is encouraging that the accuracies in our experiments are comparable to camera-camera stereo setups and outperform another of other target-based calibration approach. This shows that the proposed algorithm reliably integrates the point cloud with the intensity image. As an example application, we use the calibration results to obtain ground-truth distance images for range cameras. Furthermore, we utilize this data to investigate the accuracy of the Microsoft Kinect V2 time-of-flight and the Intel RealSense R200 structured light camera.
Response to inhaled loxapine in patients with schizophrenia or bipolar I disorder: PANSS-EC responder analyses
Authors: Zeller Scott , Zun Leslie , Cassella James V. , Spyker Daniel A. , Yeung Paul P.
Published: November 2017

Background

Efficacy of inhaled loxapine 5 or 10 mg in treating agitation was shown using the Positive and Negative Syndrome Scale – Excited Component (PANSS-EC) in two Phase III randomised, double-blind, placebo-controlled trials in 344 agitated patients with schizophrenia and 314 patients with bipolar I disorder (Clinicaltrials.gov: NCT00628589, NCT00721955).

Aims

To examine the five individual items comprising the PANSS-EC and the percentage of patients achieving a clinical response (reduction of ≥40%) in PANSS-EC (Response-40) for these two studies.

Method

Response-40 was examined at the primary end-point (2 h) and over time.

Results

Response-40 and each PANSS-EC item score were statistically significant v. placebo at 2 h and at each assessment time point for both doses.

Conclusions

Inhaled loxapine produced rapid improvement in agitated patients with schizophrenia or bipolar I disorder, achieving Response-40 at the first assessment (10 min post dose). These results highlight the effectiveness of loxapine across all components of agitation as measured by the PANSS-EC.
Cell Network-Based Formulas for Fast Determination of Flexural Stiffness Reduction of U-Shaped Core Shear Walls
Authors: Yang Yicheng , Yemmaleni Sai , Song Ikkyun , Cho In Ho
Published: November 2017

Reinforced concrete (RC) core shear wall is one of the most widely used earthquake-resisting systems. Degradation of a core wall's flexural stiffness is vital for understanding the natural frequency shift of the damaged building. But it is hard to capture, often necessitating complex finite element analyses (FEAs). This study seeks to provide an efficient tool to quickly determine the remaining flexural stiffness of U-shaped core walls. Importantly, the tool is designed to require only the easy-to-collect observational damage information. Of primary novelty is a network of microscopic unit cells, each consisting of nonlinear concrete and steel springs along with a compression-only gap. Validations with three U-shaped walls tested under complex and multidirectional loading paths show that the proposed formulas appear promising in quickly determining the trend of degrading flexural stiffness compared with a high-precision multiscale FEA program. All the formulas written in Matlab codes are made publicly available. Using the portable formulas running on a laptop, practicing engineers and researchers will be able to swiftly diagnose core U-shaped walls after quick on-site or laboratory observations.
Baseline Correction of Digital Accelerograms from Field Testing of a Seismically Isolated Building
Authors: Athanasiou Anastasia , Oliveto Giuseppe , Ponzo Felice
Published: November 2017

A three-story reinforced-concrete building in Augusta, Sicily, isolated at the base and designed according to the provisions of the latest Italian seismic regulations, was subjected to a series of push and sudden release tests in March 2013. During the tests, the displacements at the isolation level were measured along with the accelerations at each floor. The obtained records were then treated for the removal of low-frequency noise using a simple baseline-fitting scheme. The developed signal-processing scheme consists of defining the duration of the main event, removing the background noise, and using polynomial curves for the adjustment of the distorted baseline. The method does not require significant computational effort and accounts for initial and end conditions provided that these are known. Implementation of the method provides the adjusted response in terms of absolute and relative floor accelerations, velocities, and displacements, as well as interstory drifts.
Behavior of Confined Masonry Walls with Openings under In-Plane and Out-of-Plane Loads
Authors: Singhal Vaibhav , Rai Durgesh C.
Published: November 2017

Six half-scaled wall panels were tested to investigate the effect of openings on their load-carrying capacity; these walls were subjected to a sequence of slow cyclic in-plane drifts and shake table–generated out-of-plane ground motions. Two specimens were masonry-infilled frames with and without openings. The other four specimens were confined-masonry (CM) walls, with one solid wall and three walls with openings bounded by reinforced-concrete (RC) confining elements on all sides. The infill walls demonstrated higher risk of out-of-plane collapse, whereas the CM walls maintained structural integrity and out-of-plane stability. The test results clearly indicate the necessity of confinement all around the openings for good seismic performance. The confining scheme with no continuous horizontal bands was ineffective in confining wall piers at large drifts, and piers remain vulnerable to out-of-plane collapse due to severe damage. However, the wall with continuous horizontal bands at the lintel and sill levels was not only able to compensate for deficiencies in strength due to the presence of openings, but also achieved a better overall behavior due to more distributed damage and greater ductility.
A novel form of RNA double helix based on G·U and C·A+ wobble base pairing
Authors: Garg Ankur , Heinemann Udo
Published: November 2017

Wobble base pairs are critical in various physiological functions and have been linked to local structural perturbations in double-helical structures of nucleic acids. We report a 1.38-Å resolution crystal structure of an antiparallel octadecamer RNA double helix in overall A conformation, which includes a unique, central stretch of six consecutive wobble base pairs (W helix) with two G·U and four rare C·A+ wobble pairs. Four adenines within the W helix are N1-protonated and wobble-base-paired with the opposing cytosine through two regular hydrogen bonds. Combined with the two G·U pairs, the C·A+ base pairs facilitate formation of a half turn of W-helical RNA flanked by six regular Watson–Crick base pairs in standard A conformation on either side. RNA melting experiments monitored by differential scanning calorimetry, UV and circular dichroism spectroscopy demonstrate that the RNA octadecamer undergoes a pH-induced structural transition which is consistent with the presence of a duplex with C·A+ base pairs at acidic pH. Our crystal structure provides a first glimpse of an RNA double helix based entirely on wobble base pairs with possible applications in RNA or DNA nanotechnology and pH biosensors.
The First Approximation Algorithm for the Maximin Latin Hypercube Design Problem
Authors: Le Guiban Kaourintin , Rimmel Arpad , Weisser Marc-Antoine , Tomasik Joanna
Published: November 2017

In metamodeling, the choice of sampling points is crucial for the quality of the model. In this context, the maximin Latin hypercube designs (LHD), with their space-filling and noncollapsing properties, are particularly efficient. To this day, there is no polynomial time algorithm that produces optimal maximin LHDs, i.e., in which the minimum distance between two points (the separation distance) is maximal. We are interested in LHDs with a separation distance as large as possible. The algorithm we propose, IES, gives an approximate solution to the LHD problem regardless of its dimension and size with a theoretical performance guarantee. We introduce two upper bounds for the separation distance to find its approximation ratio. Its performance is compared with the best metaheuristic algorithm known for this problem, an appropriate simulated annealing scheme. Our algorithm defeats the metaheuristic algorithm for large instances of the problem while having a very short running time.
Patient safety at the crossroads
Authors: Tingle John
Published: November 2017

John Tingle, Associate Professor (Teaching and Scholarship), Nottingham Trent University, discusses some important clinical negligence and patient safety themes arising from a number of recent reports
#YoureNotAlone
Authors: Penny Alison
Published: November 2017

Children's Grief Awareness Week takes place in November. Alison Penny looks at how schools can reach out to the significant minority of pupils living with grief
Positive behaviour strategies
Authors: Burnage Steve
Published: November 2017

In a new regular series, Steve Burnage talks us through CPD ideas that can be adapted for your school. He will offer a template for a 45-minute workshop, with free handouts and slides available on our website. This instalment looks at CPD offering positive behaviour strategies to make life easier in the classroom
Making data meaningful in inspections
Authors: Rollett Stephen
Published: November 2017

Ofsted's recent inspection update urges schools to focus on ‘meaningful data’ and warns about the misuse of data. Specialist Stephen Rollett advises
Fact-Checking no Ecossistema Jornalístico Digital: Práticas, Possibilidades e Legitimação
Authors: Diniz Amanda Tavares de Melo
Published: November 2017

O artigo investiga como as plataformas de fact-checking se estão a legitimar como instituições de credibilidade no jornalismo contemporâneo. O objetivo é entender quais as suas contribuições e desafios no ecossistema digital, em que emergem novos atores, tecnologias e demandas informativas. Como referencial teórico, utilizamos os trabalhos de Graves e Cherubini (2013) e Stencel (2017) sobre a evolução do fact-checking e analisamos os princípios norteadores do fact-checking arrolados pela Rede Internacional de Checadores (2016). Nossos objetos de estudo são os projetos brasileiros Aos Fatos, Lupa e Truco no Congresso. Avaliamos seus modos de organização, suas metodologias e os sistemas de classificação de suas checagens, relacionando-os às teorizações de Charaudeau (2013) sobre produção de provas e valor de verdade. Constatamos que a checagem de factos assume crescente importância na cobertura político-administrativa mundial, ao munir os cidadãos de informações relevantes e confiáveis.
[Recensão a] Nico Carpentier, Media e Participação
Authors: Montargil Filipe
Published: November 2017

https://doi.org/10.14195/2183-6019_5_8
Hiponatremia pada Anak Pasca Tindakan Operasi : Etiologi dan Faktor-faktor yang Berhubungan
Authors: Arifin Angelina , Pudjiadi Antonius H. , Handryastuti Setyo , Amir Idham , Ifran Evita B. , Karyanti Mulya R.
Published: November 2017

Latar belakang. Kejadian hiponatremia pada anak pasca-operasi berkisar antara 20-40%. Hiponatremia yang tidak terdeteksi dapat meningkatkan mortalitas dan menyebabkan luaran neurologis yang buruk. Beberapa mekanisme yang berperan adalah sindrom hormon antidiuretik tidak tepat (SHATT) dan sick cell syndrome (SCS). Tujuan. Mengetahui insidens hiponatremia pada anak pasca-operasi, kemungkinan penyebab yang melatarbelakangi, serta faktor yang berhubungan.Metode. Penelitian potong lintang analitik dilakukan di ruang perawatan intensif terhadap anak berusia 1 bulan sampai 18 tahun yang menjalani tindakan operasi mayor dan masuk ruang perawatan intensif pediatrik RSCM selama bulan Mei sampai Desember 2016.Hasil. Terdapat 65 subyek menjalani operasi mayor, 87,69% dilakukan secara elektif, jenis operasi terbanyak adalah hepato-gastrointestinal (38,46%) dan muskuloskeletal (20,00%). Kadar natrium plasma pasca-operasi turun, kejadian hiponatremia 43,07% dan 26,16% pada 12 dan 24 jam pasca-operasi. Nilai osmolalitas plasma yang normal atau meningkat dan osmolalitas urin >100 mOsm/kg. Sebanyak 70% subyek hiponatremia memiliki natrium urin >30 mEq/L. Faktor yang berhubungan dengan hiponatremia 12 jam pasca-operasi adalah status kegawatdaruratan operasi (p=0,007) dan perdarahan intraoperatif (p=0,024), sedangkan pada 24 jam pasca-operasi hanya status kegawatdaruratan operasi (p=0,001).Kesimpulan. Terdapat 43,07% dan 26,16% subyek yang mengalami hiponatremia pada 12 dan 24 jam pasca-operasi mayor. Sindrom hormon antidiuretik tidak tepat tidak terbukti menjadi penyebab utama terjadinya hiponatremia, dan hiponatremia translokasional pada SCS mungkin berperan. Hiponatremia pasca-operasi berhubungan dengan status kegawatdaruratan operasi dan jumlah perdarahan intraoperatif.
A critical review of production factors that influ-ence egg quality traits
Authors: John-Jaja Sylvia , Abdullah Abdur-Rahman , Nwokolo Samuel
Published: November 2017

The global poultry industry has experienced significant changes in the methods used to harvest and process the fresh egg over the past century. Applications of animal genetics and breeding have significantly increased in line speed for poultry operation. In this study aims at reviewing production factors that influence egg quality traits across the globe. The production factors so far utilized were classified into three main categories and presented based on their influencing capacity. For this purpose, two types of search criteria to find publications relevant to the scope of this review were employed. The first type was an automatic search performed on the following publishers' databases: ScienceDirect, Google's scholar, researcher gates, academia. The second type was a manual search on conferences, recent theses and dissertation that have not been published in journals from numerous Babcock University. Generally, 23 publications were reported for the breed; 17 for housing, and 19 for age of the breed after excluding studies that do not focus explicitly on breed, housing and age of the bird as production factors that influenced egg quality traits out of 183 potential relevant articles identified from January 2001 to December 2016. Thus, this review would provide animal genetics and breeding researchers in terms of identifying the most potent breed, adequate housing system and precise age for optimum production of birds with high quality.
The effect of different training programs on throwing accuracy of elite female handball players
Authors: Eler Nebahat , Eler Serdar
Published: November 2017

The aim of this study is to examine the acute effect of different training programs applied to elite female handball players on throwing accuracy. 14 elite female players were participated in the study. The mean age of the participating players was 28.64 ± 9.88 (years), the mean height length was 176.50 ± 4.86 (cm), the mean body weight was 68.07 ± 2.12 (kg) and the mean sport age was 14.36 ± 4.89 (years). On different days, a technical training program, maximal strength training program, strength endurance training program and speed power training program have been implemented to the participating players in the research.  Before and after training, the players throwing the ball from their area to the specific points of goal and the percentage of accuracy was determined. As a result; there was a significant difference between before and after maximal strength training  the mean values of throwing accuracy (p<0,05) but there was no significant difference before and after other training programs (p> 0,05). This result indicates that acute maximal strength training has a negative effect on throwing accuracy.
A comparison of postoperative morphometric and hemodynamic changes between saphenous vein and left internal mammary artery grafts
Authors: Fan Tingting , Feng Yundi , Feng Feng , Yin Zhongjie , Luo Dayou , Lu Yuan , Xu Yingjin , Tan Wenchang , Huo Yunlong
Published: November 2017

There is higher long‐term failure of the saphenous vein graft (SVG) compared with the left internal mammary artery (LIMA) graft, which is affected by the hemodynamic environment. A comprehensive analysis of postoperative structure‐function changes is important to study the atherogenesis in the SVG. A comparison of morphometric and hemodynamic parameters was carried out between LIMA grafts and SVGs and between different time points postoperatively. Various parameters were obtained from the image reconstruction and flow simulation in patients, who underwent CT exams for ~1 year, 5 and 10 years after revascularization. Morphometric data showed a decrease in lumen size in the entire SVG and anastomosis of different patients in a sequence of ~1 year, 5 and 10 years postoperatively despite negligible changes of LIMA size. Computational results indicated the fourfold increased surface area ratio (SAR) of low time‐averaged wall shear stress (TAWSS) in the SVG and anastomosis at postoperative 10 years than that at postoperative ~1 year. The SAR of high TAWSS gradient (TAWSSG) at the distal anastomosis between SVG and coronary arteries was significantly higher (14 ± 9% vs. 6 ± 8%) than that in the LIMA group at postoperative ~1 year. There were strong correlations between morphometric and hemodynamic parameters in the SVG and distal anastomosis at various time points postoperatively, which showed deterioration relevant to persistent diffuse diseases at postoperative ~10 years.
MiR‐335 overexpression impairs insulin secretion through defective priming of insulin vesicles
Authors: Salunkhe Vishal A. , Ofori Jones K. , Gandasi Nikhil R. , Salö Sofia A. , Hansson Sofia , Andersson Markus E. , Wendt Anna , Barg Sebastian , Esguerra Jonathan L. S. , Eliasson Lena
Published: November 2017

MicroRNAs contribute to the maintenance of optimal cellular functions by fine‐tuning protein expression levels. In the pancreatic β‐cells, imbalances in the exocytotic machinery components lead to impaired insulin secretion and type 2 diabetes (T2D). We hypothesize that dysregulated miRNA expression exacerbates β‐cell dysfunction, and have earlier shown that islets from the diabetic GK‐rat model have increased expression of miRNAs, including miR‐335‐5p (miR‐335). Here, we aim to determine the specific role of miR‐335 during development of T2D, and the influence of this miRNA on glucose‐stimulated insulin secretion and Ca2+‐dependent exocytosis. We found that the expression of miR‐335 negatively correlated with secretion index in human islets of individuals with prediabetes. Overexpression of miR‐335 in human EndoC‐βH1 and in rat INS‐1 832/13 cells (OE335) resulted in decreased glucose‐stimulated insulin secretion, and OE335 cells showed concomitant reduction in three exocytotic proteins: SNAP25, Syntaxin‐binding protein 1 (STXBP1), and synaptotagmin 11 (SYT11). Single‐cell capacitance measurements, complemented with TIRF microscopy of the granule marker NPY‐mEGFP demonstrated a significant reduction in exocytosis in OE335 cells. The reduction was not associated with defective docking or decreased Ca2+ current. More likely, it is a direct consequence of impaired priming of already docked granules. Earlier reports have proposed reduced granular priming as the cause of reduced first‐phase insulin secretion during prediabetes. Here, we show a specific role of miR‐335 in regulating insulin secretion during this transition period. Moreover, we can conclude that miR‐335 has the capacity to modulate insulin secretion and Ca2+‐dependent exocytosis through effects on granular priming.
Performance Motivation of Elite Athletes, Recreational Athletes and Non-Athletes
Authors: Šmela Pavel , Pačesová Petra , Kraček Stanislav , Hájovský Dan
Published: November 2017

The aim of the paper is to widen knowledge about motivation of elite, recreational athletes and non-athletes. Participants from the elite athletes group (n = 35, 16.7 ± .70 years old) were football players of the Slovak national team. Recreational athletes (n = 31, 16.8 ± .80 years old) and non-athletes (n = 29, 15.7 ± .60 years old) are visiting Grammar School in Zvolen. D-M-V standardized questionnaire was used to determine performance motivation. The Kolmogorov-Smirnov's test disconfirmed the null hypothesis on the normality of data. We used the non-parametric Kruskal-Wallis and Mann-Whitney U tests to determine the statistical significance of the differences. The results showed that there were significant (p .0.01) differences with large effect size (η2≥ .14) in all the three (the performance motives scale, the anxiety inhibiting performance scale and the anxiety supporting performance scale) dimensions among the research groups. The motivation of elite athletes is significantly higher (p = .048; r = .25) compared to the recreational athletes. Also, compared to the non-athletes, the level of performance motivation is significantly higher (p = .002; r = .51) in the elite athletes. Based on the results of the study we can formulate the statement that the level of performance motivation is contingent on the level of sport activity.
Teaching Games for Understanding: A Comprehensive Approach to Promote Student’s Motivation in Physical Education
Authors: Hortigüela Alcalá David , Hernando Garijo Alejandra
Published: November 2017

It seems important to consider students’ attitudes towards physical education (PE), and the way they learn sports. The present study examines students’ perceptions of motivation and achievement in PE after experiencing three consecutive sport units. Two hundred and thirty seven students from the 1st, 2nd, 3rd, and 4th grade in a high school in Burgos (Spain) and two teachers agreed to participate. They were divided into two groups in order to compare two instructional approaches. The experimental group (A), 128 students, experienced Teaching Games for Understanding (TGfU), while the control group (B), 109 students, experienced a technical-traditional approach. Each group was taught by a different teacher. The study followed a mixed-method research design with quantitative (questionnaire) and qualitative (interview) data. Results revealed that group A showed greater motivation and achievement in PE than group B. Significant differences were found in achievement. Participants with better academic results in group A were more positive in sport participation. Meanwhile, students who practiced more extracurricular sports in group B were more actively involved in sport. Teachers disagreed greatly on the way sport should be taught in PE.
The Cognitive and Motivation Intervention Program in Youth Female Volleyball Players
Authors: Claver Fernando , Jiménez Ruth , Gil-Arias Alexander , Moreno Alberto , Moreno M. Perla
Published: November 2017

This study, grounded in Self-Determination Theory (Deci and Ryan, 1985, 2002) was aimed to determine the influence of a cognitive-motivational intervention program, to improve the basic psychological need satisfaction of autonomy and competence, autonomous motivation, procedural knowledge, perceived performance and sport commitment, in youth volleyball players. Participants included 34 Under-19 female volleyball players. A quasi-experimental design was carried out with an experimental group (n = 16; M = 17.45; SD = .45) and a control group (n = 18; M = 16.64; SD = .70). The experimental group followed a multidimensional intervention program comprised of 24 sessions held over three months (two training sessions per week). It was based on two strategies: giving athletes the possibility of choice in specific training tasks (proposing training situations with several action alternatives) and questioning (cognitively involving players through tactical questions). A repeated-measures MANOVA 2 (group: experimental and control) x 2 (time: pre-test and post-test) was used to analyse the effect of Group x Time interaction. The results of the inter-group analysis showed significant differences in the post-test measurement between the experimental group and the control group (in favour of the experimental group) in the variables: basic psychological need satisfaction of autonomy and competence, autonomous motivation, procedural knowledge, perceived performance and sport commitment. Given the relevance of the cognitive-motivational processes, not only for performance but also for sport commitment, this intervention has important implications for sport coaching.
Motivational Antecedents of Well-Being and Health Related Behaviors in Adolescents
Authors: Balaguer Isabel , Duda Joan L , Castillo Isabel
Published: November 2017

Grounded in the Achievement Goal Theory framework of motivation and optimal functioning, there were two objectives of this study: (a) to test a model hypothesizing links between personal theories of school achievement, indices of the quality of academic engagement, wellbeing, and health-related behaviors, and (b) to explore whether the hypothesized model was invariant across gender groups. A multisection questionnaire pack tapping the targeted variables was administered to 967 teenagers (475 boys and 492 girls) aged between 11 to 16 years old. Structural equation modeling analysis revealed that Task theory of achievement predicted positively satisfaction in school and negatively boredom in school. An Ego theory of achievement was linked to higher levels of boredom in school. Satisfaction in school corresponded to higher life satisfaction, while boredom was negatively related. Higher life satisfaction was associated with lower tobacco, alcohol and marijuana consumption, more healthy food intake and greater levels of physical activity. The results revealed partial invariance of the model by gender. The quality of adolescents’ involvement in the classroom holds important implications for adolescent’s well-being and their health related behaviors. Interventions on the creation of a task-involving motivational climate in the school are proposed to promote healthy lifestyles among young people.
Coherent multicore methodology and tooling
Authors: Reinkemeier Philipp , Ittershagen Philipp , Dieudonne Laurent , Diebold Philipp
Published: November 2017

In the mobility domains functions are often realized by software running on Electronic Control Units (ECU)s, which are
interconnected in a network of ECU. Nowadays there is a trend to move to ECUs with multicore processors which imposes
a major challenge: An increasing degree of parallelism. This additional parallelism when migrating existing software that
has been developed for singlecore systems, to a multicore system, has to be used in an efficient way. Furthermore, an
increase in parallelism can cause concurrent executions of software functions, which are not possible when being executed
on a singlecore ECU. This makes reasoning about the software behaviour much more difficult and also poses problems during
certification activities, when sufficient independence between functions needs to be ensured. Therefore tool support is
absolutely necessary to address the challenges. In this article we describe methods and tools that have been developed
and/or extended during the ARAMiS project to address particular challenges arising during the development of multicore
systems. In general these challenges result from the increase in parallelism available in multicore architectures.
Multicore system architecture aspects and deployment
Authors: Kuntz Stefan , Dieudonne Laurent
Published: November 2017

The crucial foundation in developing embedded safety-critical real-time systems based on multicore based platforms is the
capability to combined different methodologies and approaches with a sound formal description of the system
architecture. With such a system of methodologies and system architectures it is possible to develop a system satisfying
all requirements and even being able to optimize the overall system towards domain specific goals. This article discusses
activities in ARAMiS, which have been performed on system architecture level, including improvements of modeling existing
architectures and design techniques concerning reliability, independence, segregation and determinism for deployment
strategies.