bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship between nutritional status, anxiety, and depression in hospitalized diabetic patients in Turkey
Authors: Bakir Buse , Çalapkorur Sema
Published: March 2023

Objective

Anxiety and depression often coexist in patients with chronic diseases. We evaluated the nutritional status of diabetic patients and its relationship to anxiety and depression.

Methods

Demographic, clinical information (disease duration, treatment, hospitalization), and anthropometric measurements (weight, height, waist, and hip circumference) were recorded. The Hospital Anxiety and Depression Scale (HADS) was used to assess anxiety and depression.Twenty-four hour food diaries were obtained to determine daily energy and nutrient intake.

Results

Among the 222 patients in this study, rates of anxiety, depression, and anxious depression were 23.8%, 21.6%, and 12.2%, respectively. Those who skipped medication/insulin doses and did not exercise regularly had significantly higher anxiety and depression scores. Anxiety and depression scores were positively correlated with disease duration, waist circumference, waist/hip ratio, and waist/height ratio. Being married, engaging in regular exercise, and increased vitamin B6 were inversely related to anxiety and depression. According to food records, patients with anxiety and depression consumed a higher proportion of energy from dietary carbohydrates. Anxiety and depression scores were negatively related to dietary energy, protein, fat, vitamins (retinol, group B, C, and D), and mineral (K, Mg, P, Fe, Zn, Cu) intake.

Conclusions

Maintaining healthy body weight, complying with medication/insulin treatment, and engaging in regular exercise may help in the prevention of anxiety and depression in hospitalized diabetic patients in Turkey. Alternatively, anxiety and depression may adversely affect body weight, compliance with treatment, and regular exercise. Prospective studies are needed to determine the direction of causation.
Savarna Citations of Desire: Queer Impossibilities of Inter-Caste Love
Authors: Kang Akhil
Published: March 2023

Deliberations and discussions on inter-caste relationships in South Asia so far have been fixed within the confines of heterosexuality. Not only are heterosexual inter-caste relationships the default imagination of an inter-caste love, but also notions of heteronormativity dominate discussions of inter-caste love, relationship and, importantly, inter-caste marriages. In asking ‘queer’ questions about caste, this article analyses what an inter-caste dynamic means for social movements which rally around notions of love and desire or choose to reject them. This article recentres desire and intimacy into caste to imagine queer (im)possibilities of dalit love. In doing so, the article asks: where is the dalit lover? Building upon conversations and interviews with five dalit-queer scholars, intellectuals and activists, as well as provocations offered by them, this article complicates ‘inter-caste love’ itself as a site of power and politics, of social categorisation as well as of critical theorisation.
Practical, Applied, and Research-Based Teaching Strategies for Physicians
Authors: Williams Stephanie M. , Ziegler John F.
Published: March 2023

Aspiring physicians face a large amount of information that must be learned and retrieved in real time. The skills that helped medical students reach residency may not be the enough to succeed as a physician. For example, like many students, cramming the night before an exam probably helped achieve a satisfactory score. Unfortunately, cramming does not require that the information be retained and applied overtime. The content acquired in medical school is cumulative, that is, the information learned remains relevant months and even years later. Not only does content need to remembered, the knowledge must be constantly updated as new research makes some information more relevant and other information less important. Finally, the stakes as a physician are high. Forgetting a critical piece of information will not result in a lower test score, it can seriously harm patients. This article is a practical approach to teaching medical doctors, based on a literature review, including practical, scientific, and applied research and strategies ways in which teaching can be done that result in depth of learning in the resident.
The impact of Chinese foreign direct investment on host country economic growth
Authors: Ross Andrew G , Fleming Neil
Published: March 2023

Employing an institutional – FDI – economic growth lens the purpose of this paper is to identify and explain the impacts of Chinese FDI (CFDI) on host countries’ economic growth. While extensive research has been undertaken regarding determinants of CFDI, little is known about the actual outcomes of CFDI in recipient countries. Based on a sample of 22 countries over the period 2003–2018, our results identify that while general flows of FDI exhibited positive impacts on host countries’ economic growth, CFDI had a negative effect on host country economic growth. From the host country perspective, given the emphasis that is placed on FDI as an instrument of growth and development, our findings raise questions about what host countries are actually gaining from CFDI and the potential implications of whether pursuing the ‘Beijing Consensus’ as opposed to the ‘Washington Consensus’ is really in the long-term interests of countries.
The Aesthetic Emotion Lexicon: A Literature Review of Emotion Words Used by Researchers to Describe Aesthetic Experiences
Authors: Schubert Emery
Published: March 2023

The emotions that can be considered members of the set of Aesthetic Emotions (AEs) is controversial. The present study investigated the terms used by researchers in peer reviewed studies to exemplify AEs. 100 publications from 2000–2019 exemplifying AE terms were located to produced 111 AEs which were proposed as the basis of an AE lexicon. Awe, (being) moved and wonder were reliable members and without contradiction. One fifth were negatively valenced (e.g., anger, disgust), suggesting that the presence of negative AEs is generally accepted but not reliably. One quarter of the entries were also non-AEs and an additional 20 were exclusively so, producing a total of 131 terms. The lexicon is a concrete, dynamic set of examples against which to investigate extant definitions of AEs and to further develop theory. The robust presence of three terms suggests that calls to abandon the concept of AE may be premature.
Sympathetic ophthalmia in an 85-year-old female and a 90-year-old male after a non-complicated cataract surgery: a case report
Authors: Muto Tetsuaya , Machida Shigeki , Imaizumi Shinichiro
Published: March 2023

Here, two cases involving the oldest reported patients with sympathetic ophthalmia (SO) after non-complicated cataract surgery, are reported. The first case was an 85-year-old female with bilateral decreased vision and headache. The best-corrected visual acuity (BCVA) was 0.8 in the right eye and 1.0 in the left eye at the initial visit. Pseudophakia and choroidal detachments were observed in both eyes, and retinal pigment epithelium undulation was observed by optical coherence tomography. The second case was a 90-year-old male with bilateral optic disc oedema. The BCVA was 0.09 in the right eye and 0.3 in the left eye with pseudophakic eyes. Optic disc oedema and choroidal thickening were observed in both eyes. Both patients were diagnosed with SO, and corticosteroid pulse treatments were started. The BCVA of the first case improved to 0.9 in the right eye and 1.2 in the left eye, while that of the second case reached 0.3 in the right eye and 0.6 in the left eye. No recurrence was observed in either case at 12 months after the initial visit. Both elderly patients with SO were successfully treated.
‘The Citadel of Scholarship’: Rediscovering Critical IR in Millennium 1:1
Authors: Conway Philip R.
Published: March 2023

‘Critical’ international relations (IR) is usually understood to have originated in the early 1980s. However, a close reading of Vithal Rajan’s ‘An Epitaph for Detached Scholarship’, published in the inaugural issue of Millennium in 1971, tells another story. Rajan’s article was not a work of critical theory per se, but it was in tune with demands, at this time, for establishing a ‘critical university’. Promising to open up university education to all, dispensing with traditional curricula and authoritarian modes of teaching, the critical university, like Rajan’s article, has long since been forgotten. Nevertheless, this moment set the scene for the professionalised establishment of ‘critical’ academia in the decades to come. Rediscovering Rajan’s ‘Epitaph’ thus offers to reconnect critical IR with an earlier, and perhaps more generative, moment of inception. Indeed, even today, Rajan’s creative, provocative, playful text stands out as a rewardingly undisciplined contribution to the discipline.
Predicting Pedestrian Behavior by Sleep Quality and Emotional Self-Regulation
Authors: Dabirinejad Shahab , Minasian Erik , Kashani Ali Tavakoli , Rundmo Torbjorn , Afshar Ali
Published: March 2023

The behavior of pedestrians may make them more vulnerable to accidents. However, emotional self-regulation is a capability that helps individuals mitigate generally negative emotions that could affect their behavior, perception, and attention unfavorably. Therefore, emotional self-regulation is expected to play an important role in the safety of transportation network users. However, no previous studies have investigated its association with pedestrian behavior. Sleep quality is another factor affecting transportation network users’ behavior and safety. In spite of this, studies investigating the relationships between sleep quality and pedestrian safety are limited to a very narrow range of pedestrian behavior. Interestingly, sleep quality is also associated with emotional self-regulation, and the literature is relatively ambiguous, supporting both a causal (mediation) and a bidirectional relationship. In this study, a four-part questionnaire was used to collect data on 740 pedestrians’ demographics, emotional self-regulation, sleep quality, and behavior. Confirmatory factor analysis was run to determine the structure of the instrument, and structural equation models were constructed to investigate the associations between variables. The results indicated an increase in risky and aggressive behaviors, and a decrease in positive behaviors because of difficulties with emotional self-regulation and poorer sleep quality. In this study, emotional self-regulation was rejected as a mediator between sleep quality and pedestrian behavior, whereas its bidirectional relationship with sleep quality was substantiated. The findings of this study shed light on some relationships that may lead to a reduction in the likelihood of people with a diminished ability to regulate their emotions, or sleep problems being involved in traffic accidents.
Speed Control and Driver Psychophysiology Performance in Highway Uphill Sections
Authors: Wu Yanxia , Qiao Jing , Shekonya Kanda Paul , Qiao Jian’gang
Published: March 2023

Many accidents occurred in highway uphill sections. Changes in the vehicle speed may cause accidents. The driver’s psychological state is closely related to the control of speed. In this paper, 16 participants were selected for a field driving experiment, where the speed change data of a single vehicle traveling in highway uphill sections and the corresponding participants’ physiological performance data during the experiment were all collected. Then the instantaneous speed, eye movement parameters, and heart rate (HR) of each participant were analyzed with statistical methods. The results reveal that deceleration (or stop acceleration) events before the uphill crest occur in more than 80% of the uphill sections when there is no other interference. This phenomenon occurs because the participant’s sight distance is restricted in these segments. The location of the slow-down segment was closely dependent on the slope gradient and the driving speed. In the slow-down segments, the participants have the longest fixation time and the lowest saccade and blink time compared with those in front of and behind the slow-down segments. Moreover, the driver’s HR increase is the highest. These results can serve as guidance for highway designers who develop safety measures for uphill sections.
Coupling Train-Track Models with the Discrete Element Method for a More Realistic Simulation of Ballasted Track Dynamic Behavior
Authors: Liu Zhongyi , Feng Bin , Tutumluer Erol
Published: March 2023

Train-track interaction models are widely used to simulate the dynamic responses of train and track components. In a conventional train-track analytical model, the ballast layer is often simplified as mass blocks, interacting with other components through a spring and dashpot system. Such an idealization ignores the particle-level information, that is interaction of different sized and shaped aggregates and related degradation characteristics linked to fouling behavior of the ballast layer. On the other hand, realistic ballast models based on the discrete element method (DEM) can capture the particle-level information but require predefined external loading patterns as inputs to mimic the train passages. To overcome such drawbacks of train-track and DEM models, this paper proposes to couple the two calibrated models together to build a more realistic ballasted track model for predicting dynamic responses of the train and track. The coupled model was first validated with detailed field data collected from Amtrak’s Northeast Corridor. The validated model was then used to study the effects of crosstie spacing realizing that a smaller crosstie spacing than regular often results in a higher construction cost. Increasing crosstie spacing, however, was found to result in larger track displacements, crosstie accelerations and reaction forces, particle accelerations, and local average normal contact forces. Therefore, vibration patterns with a smaller crosstie spacing were more stable. Such observations suggest that crosstie spacing plays an essential role in controlling track dynamic responses, and an optimum crosstie spacing could be determined by using the newly introduced coupled model.
Evaluation of Flood-Vulnerable Pavement Network in Support of Resilience in Pavement System Management
Authors: Hong Feng , Wu Hui , Li Jenny , Paul Elizabeth
Published: March 2023

Transportation systems play a pivotal role in the nation’s economic and societal development. Transportation assets, such as pavements and bridges, are inevitably subject to the effects of climate and environment. These stressors mainly include flood, precipitation, heat, wildfire, and wind. Specifically, more extreme weather events, such as hurricanes and snowstorms, have occurred in recent years. This requires stakeholders to better prepare transportation infrastructure resilience in planning, design, construction, and management. Its importance is manifested through nationwide policy and state-level practice. For example, in Bipartisan Infrastructure Law, the FHWA directs all state DOTs to incorporate resilience in their transportation asset management plans. A critical element in resilience is to evaluate the effect of climatic or environmental stressors on facilities’ performance. This study examines the impact of flood on the TxDOT-managed pavement network. It proposes a method to evaluate the flood-vulnerable pavement network in the context of resilience. First, the GIS tool is used to overlap a 100-year frequency flood with the road network to identify weak pavement sections subject to flood risk. Second, a simulation is run to determine sections affected by flood over a 10-year analysis horizon. Then, different deterioration models are used to predict the network-level pavement performance, to reflect (1) normal deterioration without flood, (2) optimistic accelerated deterioration under flooding, and (3) pessimistic accelerated deterioration under flooding. It is found that the network-level pavement will experience varying levels of performance reduction, owing to a 100-year flood impact. The quantified performance change can serve to enhance infrastructure resilience preparation for more reliable pavement system management.
Exosomes Derived From Kartogenin-Preconditioned Mesenchymal Stem Cells Promote Cartilage Formation and Collagen Maturation for Enthesis Regeneration in a Rat Model of Chronic Rotator Cuff Tear
Authors: Cai Jiangyu , Xu Junjie , Ye Zipeng , Wang Liren , Zheng Ting , Zhang Tianlun , Li Yufeng , Jiang Jia , Zhao Jinzhong
Published: March 2023

Background:

Poor tendon-to-bone healing in chronic rotator cuff tears (RCTs) is related to unsatisfactory outcomes. Exosomes derived from mesenchymal stem cells reportedly enhance rotator cuff healing. However, the difficulty in producing exosomes with a stronger effect on enthesis regeneration must be resolved.

Purpose:

To study the effect of exosomes derived from kartogenin (KGN)-preconditioned human bone marrow mesenchymal stem cells (KGN-Exos) on tendon-to-bone healing in a rat model of chronic RCT.

Study Design:

Controlled laboratory study.

Methods:

Exosome-loaded sodium alginate hydrogel (SAH) was prepared. Moreover, exosomes were labeled with 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindotricarbocyanine iodide (DiR) or 1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate (Dil) for in vivo tracking. Bilateral rotator cuff repair (RCR) was conducted in an established chronic RCT rat model. A total of 66 rats were randomized to control, untreated exosome (un-Exos), and KGN-Exos groups to receive local injections of pure SAH, un-Exos, or KGN-Exos SAH at the repaired site. The presence of DiR/Dil-labeled exosomes was assessed at 1 day and 1 week, and tendon-to-bone healing was evaluated histologically, immunohistochemically, and biomechanically at 4 and 8 weeks.

Results:

Both un-Exos and KGN-Exos exhibited sustained release from SAH for up to 96 hours. In vivo study revealed that un-Exos and KGN-Exos were localized to the repaired site at 1 week. Moreover, the KGN-Exos group showed a higher histological score and increased glycosaminoglycan and collagen II expression at 4 and 8 weeks. In addition, more mature and better-organized collagen fibers with higher ratios of collagen I to collagen III were observed at 8 weeks in the tendon-to-bone interface compared with those in the control and un-Exos groups. Biomechanically, the KGN-Exos group had the highest failure load (28.12 ± 2.40 N) and stiffness (28.57 ± 2.49 N/mm) among the 3 groups at 8 weeks.

Conclusion:

Local injection of SAH with sustained KGN-Exos release could effectively promote cartilage formation as well as collagen maturation and organization for enthesis regeneration, contributing to enhanced biomechanical properties after RCR.

Clinical Relevance:

KGN-Exos injection may be used as a cell-free therapeutic option to accelerate tendon-to-bone healing in chronic RCT.
Repairing Avascular Meniscal Lesions by Recruiting Endogenous Targeted Cells Through Bispecific Synovial-Meniscal Aptamers
Authors: Chen Zhong , Deng Xing-Hao , Jiang Chuan , Wang Jing-Song , Li Wei-Ping , Zhu Ke-Long , Li Yu-Heng , Song Bin , Zhang Zheng-Zheng
Published: March 2023

Background:

Tissue engineering is a promising treatment option for meniscal lesions in the avascular area, but a favorable cell source and its utilization in tissue-engineered menisci remain uncertain. Therefore, a more controllable and convenient method for cell recruitment is required.

Hypothesis:

Circular bispecific synovial-meniscal (S-M) aptamers with a gelatin methacryloyl (GelMA) hydrogel can recruit endogenous synovial and meniscal cells to the site of the defect, thereby promoting in situ meniscal regeneration and chondroprotection.

Study Design:

Controlled laboratory study.

Methods:

Synovial and meniscal aptamers were filtered through systematic evolution of ligands by exponential enrichment (SELEX) and cross-linked to synthesize the S-M aptamer. A GelMA-aptamer system was constructed. An in vitro analysis of the bi-recruitment of synovial and meniscal cells was performed, and the migration and proliferation of the GelMA-aptamer hydrogel were also tested. For the in vivo assay, rabbits (n = 90) with meniscal defects in the avascular zone were divided into 3 groups: repair with the GelMA-aptamer hydrogel (GelMA-aptamer group), repair with the GelMA hydrogel (GelMA group), and no repair (blank group). Regeneration of the repaired meniscus and degeneration of the cartilage were assessed by gross and histological evaluations at 4, 8, and 12 weeks postoperatively. The mechanical properties of repaired menisci were also evaluated.

Results:

In vitro synovial and meniscal cells were recruited simultaneously by the S-M aptamer with high affiliation and specificity. The GelMA-aptamer hydrogel promoted the migration of targeted cells. Compared with the other groups, the GelMA-aptamer group showed enhanced fibrocartilaginous regeneration, lower cartilage degeneration, and better mechanical strength at 12 weeks after meniscal repair.

Conclusion/Clinical Relevance:

Bispecific S-M aptamers could be used for avascular meniscal repair by recruiting endogenous synovial and meniscal cells and promoting fibrocartilaginous regeneration.
A Modified Lemaire Lateral Extra-articular Tenodesis in High-Risk Adolescents Undergoing Anterior Cruciate Ligament Reconstruction With Quadriceps Tendon Autograft: 2-Year Clinical Outcomes
Authors: Green Daniel W. , Hidalgo Perea Sofia , Brusalis Christopher M. , Chipman Danielle E. , Asaro Lori A. , Cordasco Frank A.
Published: March 2023

Background:

The incidence of anterior cruciate ligament (ACL) reconstruction (ACLR) in children and adolescents has increased significantly, and many such patients are at increased risk for ACL retear. Lateral extra-articular tenodesis (LET) may be performed in conjunction with ACLR to reduce the risk of ACL retear.

Purpose:

To evaluate the 2-year clinical outcomes of ACLR with soft tissue quadriceps tendon (QUAD) autograft performed with a concomitant LET using a modified Lemaire technique in skeletally immature patients.

Study Design:

Case series; Level of evidence, 4.

Methods:

A consecutive series of adolescent patients who underwent QUAD autograft ACLR and LET with a minimum of 2 years of follow-up data were analyzed retrospectively. ACLR techniques, including all-epiphyseal and complete transphyseal, were indicated based on skeletal age. Outcome measures included return to sports, concomitant or subsequent surgical procedures, and multiple patient-reported outcome measures, including Single Assessment Numeric Evaluation (SANE), Pediatric International Knee Documentation Committee (Pedi-IKDC), and Hospital for Special Surgery Pediatric Functional Activity Brief Scale (HSS Pedi-FABS) scores.

Results:

The final cohort included 49 consecutive adolescent patients aged 11 to 16 years (mean, 14.2 ± 1 years) with a minimum follow-up of 2 years. One patient was lost to follow-up. Of the patients included in the study (N = 48; 27 male, 21 female), 98% participated in high-risk competitive sports. Two (4%) patients were undergoing revision ACLR. Thirty-eight (79%) patients underwent complete transphyseal, and 10 (21%) patients underwent all-epiphyseal ACLR. Sixteen (33%) patients had subsequent surgical procedures, including 5 contralateral ACLR, 4 meniscal surgery, 4 QUAD autograft scar revision, 4 irrigation and debridement (2 patients, 2 each), and 3 hardware removal (2 for hemi-epiphysiodesis and 1 tibial socket button removal) procedures. The rate of graft rupture was 0%. At a mean follow-up of 3.4 ± 1.2 years (range, 2-7 range), the mean SANE score was 93, the mean Pedi-IKDC score was 89, and the mean HSS Pedi-FABS score was 23. The return-to-sports rate was 100%.

Conclusion:

An LET performed concomitantly with an ACLR is safe and should be considered as a concomitant procedure for adolescent patients with nonmodifiable risk factors who are at high risk of retear.
Developing a Single-Item General Self-Efficacy Scale: An Initial Study
Authors: Di Weiwei , Nie Youyan , Chua Bee Leng , Chye Stefanie , Teo Timothy
Published: March 2023

General self-efficacy represents the global sense of personal capability across various situations and tasks. The aim of the present study was to develop and validate a single-item general self-efficacy scale which balances practical demands and psychometric concerns. The psychometric properties of the proposed Single-Item General Self-Efficacy Scale (GSE-SI) were examined among 231 Singaporean adults. Results based on three statistical methods demonstrated good reliability (.594 .607 and .726, respectively, M = .642), as compared with the reliability scores from other single-item scales. It also showed satisfactory criterion-related validity evidence (i.e., correlation with a multiple-item general self-efficacy scale, r = .795). Validity evidence based on relationships with other constructs was supported by the correlations between the scores of general self-efficacy and the scores of six relevant constructs (i.e., positive correlations with life satisfaction and positive emotions, negative correlations with negative emotions, task and perceived stress, and illness symptoms). More importantly, the GSE-SI and multiple-item scale scores showed consistent correlation patterns with their relevant constructs. Both GSE-SI and multiple-item scale scores significantly discriminated between the three clusters in a similar pattern. The present results show that the GSE-SI is a reliable and valid measure of general self-efficacy and can be recommended in future research to complement the constraints of multiple-item scales.
Introduction: Risk and Uncertainty in the Early Modern World
Authors: Wade Lewis , Dreijer Gijs , Hope Mallory
Published: March 2023

This article introduces the various articles in this forum. It first sets the scene by showing why the maritime sector forms an excellent case study to investigate risk and uncertainty in the premodern world. Second, it problematises from a historical perspective both Frank Knight's and Douglass North's approaches to risk and uncertainty, arguing that notwithstanding the lack of data, premodern commerce could properly assess both risk and uncertainty. Third, it introduces the various articles in the forum.
Why Do Students Participate in Campus Sexual Assault Climate Surveys?
Authors: McMahon Sarah , Connor Rachel A. , Cusano Julia , Brachmann Allison
Published: March 2023

The purpose of the current study is to explore students’ reasons for participating in a campus sexual assault climate survey to determine if patterns exist based on various identities and experiences. More specifically, we were interested in the most frequently reported reasons for participating, and whether they differed by key demographic variables. As part of a campus climate survey administration at two campuses, 4,020 students responded to survey questions asking why they participated in the survey (Sample 1, n = 2,937 and Sample 2, n = 1,083). To examine which demographic variables predicted reasons for taking the survey while controlling for other potential correlates, we conducted logistic regression analyses. The reasons provided by students as to why they completed the campus climate survey differed by identity characteristics, suggesting that researchers must consider the demographic makeup of their institutions when designing sampling and recruitment plans and tailoring them to their student populations. For example, while gender emerged as salient for differing reasons for participation (e.g., women more likely to participate because of the issue’s importance and wanting their opinions heard more), intersectional analysis by race and gender indicates that White men (and Asian men, in Sample 1) most consistently indicated different reasons for participation, with significantly greater odds than their White and Asian women counterparts to participate for the cash incentives. This information could help improve the recruitment of representative samples for campus sexual assault surveys and therefore provide more accurate data that can be used to deliver effective intervention and prevention efforts.
“I Put In My Two Weeks Notice!” Employee Behavior and Wellness Prior to Exit
Authors: Moon Young-Kook , O’Brien Kimberly E.
Published: March 2023

Previous research has identified four distinct “proximal withdrawal states” among employees. That is, employees can generally be distinguished by their desire to stay or leave (e.g., “stayers” or “leavers”) and their control over this desire (e.g., “enthusiastic” versus “reluctant” staying or leaving). However, little is known about how these withdrawal states impact voluntary behavior and employee wellness. Thus, we examined these relationships in US ( n = 516) and South Korea ( n = 414). Latent profile analysis indicated that there are two profiles of stayers (i.e., embedded stayers and detached stayers) and two of seekers (i.e., dissatisfied seekers and script-driven seekers) in both samples. US and Korean profiles were consistent, except seekers differed by country based on planning, job seeking, and socio-emotional reasons. We also found that profiles differentially predicted work behaviors and wellness outcomes, such that embedded stayers showed most adaptive behavioral patterns, whereas script-driven seekers reported the least wellness.
Medical Management of Dental Abnormalities Related to Congenital Hypothyroidism in a Cat
Authors: Bates Jaclyn
Published: March 2023

A 5-month-old intact male domestic shorthair cat presenting for routine vaccinations was diagnosed with congenital hypothyroidism. His primary presenting symptom was incomplete dentition with delayed dental eruption. Congenital hypothyroidism was confirmed by baseline thyroxine (T4), free T4, and thyroid-stimulating hormone testing. The cat was treated with oral thyroid hormone supplementation and 16 weeks after initiation of therapy the cat was clinically normal with age-appropriate dentition. No surgical intervention was necessary to achieve normal dental eruption.
Analyzing the pressure and thermal efficiency of chemically synthesized nanofluids for computer cooling methods
Authors: Mariadhas Anish , R Rishi Kumar , SV Puneeth Reddy , P Bency , J Jayaprabakar , Joy Nivin , SK Sahaya Susmi , V Jayaprakash
Published: March 2023

To maintain ideal working conditions by removing heat, a particular technique must be applied. This research examines how nanofluids affect computer cooling microchannel heating devices. The experiment's working fluids are 25% Therminol-55 and 75% sprinkling water. The mixture contains silicon carbide (SiC), titanium oxide (TiO2), and zinc oxide (ZnO) nanoparticles. It includes 0.25% to 1.5% nanoparticles and flows at 0.025 to 0.080 kg/s at 25°C to 40°C. Central processing unit temperature, heat transfer rate, pressure losses, and pumping power have been examined. SiC-THERMINOL/SPRINKLING WATER at 1.5% concentration and 0.080 kg/s had a 9% lower temperature and 31% larger heat transfer coefficient than the base fluid. SiC-TL/SW has the highest pressure decrease and pumping force power compared to TiO2-TL/SW. Because nanofluid beats basic fluid in computer cooling, a little increase in pumping force power and pressure reduction may be tolerated.
Intelligent detection of fine cracks on sleepers based on improved YOLOv5 model of cascade fusion
Authors: Ling Liepeng , Xue Feng , Zhang Jianbo , Huan Yi , Chen Fengwei
Published: March 2023

The detection of cracks in sleepers is important in ensuring safe operation of trains and the crack width is a key index in this process. The traditional YOLOv5 model can not achieve satisfactory detection results in the face of large changes in the scale of the target and interference of background information in the detection process. In this paper, a method to detect and measure the fine crack of sleeper based on improved YOLOv5 model of cascade fusion and edge fitting algorithm is proposed to solve these problems. An adaptive multi-scale feature fusion technique is proposed to achieve multi-scale feature fusion efficiently and solve the problem of large changes in the scale of the target. An improved method of feature recombination of attention mechanism is used to solve the interference problem of background information. On this basis, a method based on cascade fusion is proposed to fuse the above improvements and reconstruct the structure of the YOLOv5 model. Moreover, a fitting algorithm of the crack edge is proposed to realize the precise measurement of the maximum width of the fine crack on sleepers. Finally, the process of crack detection and width measurement of sleeper is developed and the performance of the method proposed in this paper is verified by experiments through self-made data sets. The experimental results show that the precision of crack detection is increased from 84.08% to 96.86%, and the recall is increased from 78.13% to 96.46%. The increases are 12.78% and 18.33% respectively. At the same time, the average detection time is reduced from 15.23 ms to 10.04 ms. The measurement accuracy of the maximum crack width is 0.05 mm.
Wheel wear prediction for high speed railway vehicles during acceleration
Authors: Sang Hutang , Zeng Jing , Qi Yayun , Huang Caihong , Mu Jian
Published: March 2023

Wheel wear prediction for high-speed railway vehicles during the acceleration process is of great importance for the improvement of operating characteristics and the development of friction management strategy near the railway station, especially in complex climatic environments. This work analyzes and predicts the wheel wear evolution of high-speed motor cars during acceleration. Firstly, detailed dynamic models of the high-speed motor car are developed, in which a comprehensive gear transmission system is also adopted to capture the accurate dynamic responses of the motor car. Secondly, the length of the simulated track interval with different friction coefficients is set according to the Gaussian distribution function to consider the influence of the friction coefficient. Moreover, a Proportional-Integral(PI) creep controller is also introduced to meet the challenge due to varying wheel-rail contact conditions, and a wheel wear prediction model based on the aforementioned submodels is established to obtain the wheel wear evolution. Finally, simulation results of dynamic responses from the vehicle dynamic model and wheel wear prediction procedure are compared with the measured field data. The results show that the time-varying meshing stiffness from the gear transmission system will aggravate the interaction between wheel and rail and deteriorate the wheel wear. When the high-speed motor car passes through a poor adhesion zone in the acceleration, it is easier to trigger the creep controller at the low-speed period while it will not occur at the high-speed period.
Aerostructural performance improvement in an unmanned long endurance aircraft using adaptive wing concept
Authors: Sampath Ashok K , Padmanabhan Madhusudan A , Kattimani Subhaschandra
Published: March 2023

This paper presents an analytical research study to improve the aerostructural performance of an unmanned medium altitude long endurance aircraft using the adaptive wing concept. Aerodynamic drag and wing root loads are minimized by optimal scheduling of multiple trailing edge flaps located on the wing. A trim optimization process is developed specifically for this purpose. The aeroelastic model is based on finite element formulation for the structure and doublet lattice method for the aerodynamics. A nonlinear numerical lifting line method is used, in combination with airfoil wind tunnel data, to estimate the induced and total drags. Results are presented for the current aircraft configuration and a more flexible proposed configuration, thereby providing an uncommon perspective on the effect of flexibility on the adaptive wing. For example, the benefits of optimal flap deployment turn out to be greater for the flexible aircraft than for the rigid one. It is hoped that this work and its insights will also aid the multidisciplinary design optimization of future aircraft.
The influence of blade trailing edge modification on the pressure pulsation inside a two-stage centrifugal pump
Authors: Cui Baoling , An Yinchu , Han Xiaotian , Li Wenqing
Published: March 2023

Adjusting the clearance between the rotor and the stator in the centrifugal pump is an effective measure to reduce the pressure pulsation. In this paper, we investigated the influence of blade trailing edge modification on the internal unsteady flow and the performance of a two-stage centrifugal pump with the V-type trailing edge (VTE) and elliptic trailing edge (ETE). The pressure pulsation on the spherical casing and the performance were analyzed based on the experimental results for the pump with the modified blade trailing edges of the cutting depths 1 mm, 2 mm and 2.5 mm. Also the unsteady flow in the pump was numerically simulated, and the velocity and the axial vorticity intensity were analyzed to evaluate the influence of the flow on the pressure pulsation and the performance of the pump. The results show that cutting the blade trailing edge will reduce the head and efficiency of the two-stage pump, and different outlet shapes under the same cutting depth have little effect on the performance. The modified impeller makes the high velocity areas at the blade outlet away from the spherical casing wall and reduces the pressure pulsation amplitude at the main frequency. At the design flow rate, the heads decrease by 7.3%, 9.8% and 11.3%, the efficiencies decrease by 2.8%, 3.5% and 4.0%, and the pressure pulsation amplitudes at the main frequency are reduced by 29%, 10.1% and 28.7% for the ETE1, ETE2, ETE2.5 blade compared with that of original impeller. Also, the heads decrease by 6.3%, 8.0% and 9.1%, the efficiencies decrease by 3.5%, 3.9% and 4.1%, and the pressure pulsation amplitudes at the main frequency are reduced by 3.2%, 11.7% and 38.1% for VTE1, VTE2, VTE2.5 blade. When the cutting depth is large, the trailing edge of the blade has a large vortex intensity. This may cause the energy loss and lead to the decrease of the efficiency and head. Considering the performance and unsteady pressure pulsation of the two-stage pump, the impeller with VTE1 blade has certain reference significance for engineering application.
Predictors of severe hemolytic anemia and its impact on major outcomes in systemic lupus erythematosus: Data from a multiethnic Latin American cohort
Authors: González Luis Alonso , Alarcón Graciela S. , Harvey Guillermina B , Quintana Rosana , Pons-Estel Guillermo J , Ugarte-Gil Manuel F , Vásquez Gloria , Catoggio Luis J , García Mercedes A. , Borba Eduardo F , Da Silva Nilzio A , Tavares Brenol João C , Toledano Marlene Guibert , Massardo Loreto , Neira Oscar , Pascual-Ramos Virginia , Amigo Mary-Carmen , Barile-Fabris Leonor A , De La Torre Ignacio García , Alfaro-Lozano José , Segami María I , Chacón-Díaz Rosa , Esteva-Spinetti María H , Iglesias-Gamarra Antonio , Pons-Estel Bernardo A
Published: March 2023

Objective

To determine the predictors of the occurrence of severe autoimmune hemolytic anemia (AIHA) and its impact on damage accrual and mortality in SLE patients.

Methods

Factors associated with time to severe AIHA (hemoglobin level ≤7 g/dL) occurring from the onset of SLE symptoms were examined by Cox proportional hazards regressions. The association of severe AIHA with mortality was examined by logistic regression analyses while its impact on damage was by negative binomial regression.

Results

Of 1,349 patients, 49 (3.6%) developed severe AIHA over a mean (SD) follow-up time of 5.4 (3.8) years. The median time from the first clinical manifestation to severe AIHA was 111 days (IQR 43–450). By multivariable analysis, male sex (HR 2.26, 95% CI 1.02–4.75, p = 0.044), and higher disease activity at diagnosis (HR 1.04, 95% CI 1.01–1.08, p = 0.025) were associated with a shorter time to severe AIHA occurrence. Of the SLEDAI descriptors, only hematologic (leukopenia and/or thrombocytopenia) showed a certain trend toward significance in the multivariable analysis (HR 2.36, 95% CI 0.91–6.13, p = 0.0772). Severe AIHA contributed neither to damage nor to mortality.

Conclusions

Severe AIHA occurs during the early course of SLE. Male sex and higher disease activity at diagnosis emerged as independent predictors of a shorter time to severe AIHA occurrence. Although not statistically significant, hematological abnormalities at SLE diagnosis could predict the occurrence of severe AIHA in a shorter time. Damage and mortality did not seem to be impacted by the occurrence of severe AIHA.
Validation of a monoclonal unconjugated estriol antibody for use in prenatal maternal serum screening
Authors: Lambert-Messerlian Geralyn M , Bestwick Jonathan P , Wald Nicholas J
Published: March 2023

Objectives

Unconjugated estriol (uE3) is used as a marker for fetal aneuploidy in maternal serum screening tests. The goal of this study was to examine the validity of a new immunoassay for uE3 that uses a monoclonal antibody (m-uE3) rather than the more commonly used polyclonal antibody (p-uE3).

Setting

Assays were performed in the Special Chemistry laboratory at Women and Infants Hospital of Rhode Island.

Methods

Residual fresh ( n = 100) and frozen ( n = 533) second trimester serum samples from routine clinical care were tested using p-uE3 and/or m-uE3 assays. Assay results were compared between methods using Bland–Altman plots. A median equation was developed for m-uE3 results. Down syndrome risks were compared between the two assays in a case–control sample set (21 cases each matched with five controls for the completed week of gestation, duration of freezer storage and race).

Results

Log-transformed serum uE3 levels were highly correlated between the assays ( r = 0.93, p < 0.001), with the m-uE3 assay levels yielding, on average, 23% higher (standard deviation of differences in log uE3 concentrations = 0.07) results. Assay and gestation-based median equations were calculated and used to convert m-uE3 concentrations to multiples of the median (MoM). The m-uE3 MoM values fit a log Gaussian distribution well with a log standard deviation of 0.11. Down syndrome risk results were not significantly different between assays.

Conclusions

The m-uE3 assay, with results expressed in MoMs, is suitable for screening and as a monoclonal-based assay offers the advantage of a predictable and indefinite supply of antibody to perform the assay.
The faceless court? The role of individual CJEU members
Authors: Gragl Paul
Published: March 2023

The CJEU is perceived to be a rather faceless court due to the principle of collegiality that is supposed to suppress individuality in its inner workings. This paper argues that this is not necessarily true in all cases and discusses instances wherein individual faces of the CJEU's members become discernible, in particular in their roles as President and Vice-President, respectively, the judge-rapporteur, Advocates General, single judges at the General Court, during public oral hearings, as litigants themselves, and of course in their academic publications. It also shows that judicial visibility can, in itself, certainly be construed to support the legitimacy of a court, but that it can, at the same time, also undermine its functioning, especially when judges are, as appointees, dependent on the will of their home Member State and others in the Council. Overall, it will be demonstrated that there are various situations in which individual CJEU members may emerge from an otherwise anonymous bench and play important judicial roles as individuals, thus rebutting the long-standing presumption that the CJEU is a faceless court.
Indigenous peoples and accounting: A systematic literature review
Authors: Vidwans Mohini , De Silva Tracy-Anne
Published: March 2023

The purpose of this systematic literature review on ‘indigenous peoples and accounting’ is to identify major themes and derive insights to guide future research and policy agendas. We also investigate whether accounting has been used by the indigenous peoples for emancipation. Seventy-one peer-reviewed journal articles are categorised into three clusters (imperialism, accounting profession and need for emancipation) and analysed. This review positions accounting not as a mere neutral, benign, technical practice but as a racist and ethnocentric tool through the context in which it has been practised. Accounting was an integral part of imperial rule, inheriting colonial structures and separating and reducing indigenous peoples from their own cultures and structures. Indigenous accountants remain severely under-represented; indigenous autonomy, voice and participation are vital for transforming the ethnocentric systems that have led to the devaluation of indigenous peoples. For effecting change we identify a need to focus on forward-looking solutions and how indigenous cultural values can contribute to a more enabling accounting.
A Cognitive Behavioral Family Therapy Approach: The Impact of Divorce on a Hispanic Adolescent with an Eating Disorder
Authors: Gomez Eunice , Tadros Eman
Published: March 2023

Each year, millions of marriages end up in divorce which can cause teenagers to experience multiple physiological and psychological issues. Cognitive Behavioral Family Therapy (CBFT) has become increasingly popular among family therapists in recent decades, who utilize it either as a stand-alone technique within a system perspective or integrated into other approaches with couples and family therapy. There is a gap in the literature regarding the utilization of CBFT to a divorced family of Hispanic/Latinx descent with an adolescent who developed an eating disorder. The overall aim of this article is to provide insight for marriage and family therapists (MFTs), other mental health professionals, professors/teachers, researchers, and virtually everyone. The researchers hope to provide the ability to conceptualize eating disorders in a way that promotes empathy, compassion, and awareness. Barriers unique to Hispanic/Latinx families, clinical implications, and future directions will be discussed.
Examining the Impact of COVID-19 on Education and Service Access for Diverse Families of Young Children With and Without Developmental Delays
Authors: Martin Ann Marie , McIntyre Laura Lee , Neece Cameron
Published: March 2023

The rapid transition to virtual learning due to the COVID-19 pandemic created unprecedented challenges that significantly impacted caregivers of young children, particularly those with developmental delays and children from non-English speaking households (Valicenti-McDermott et al., 2022). The current study aims to describe caregivers’ concerns regarding the COVID-19 pandemic in general and specific educational concerns following school closures, and to determine whether their concerns varied as a function of whether the child had a developmental delay or the parent's ethnicity. Results revealed that caregivers of children with DD endorsed a greater number of general and education-specific COVID-19 concerns compared to caregivers of TD children, and non-Latinx caregivers of children with DD reported more general COVID-19 concerns compared to Latinx caregivers of children with DD. With respect to education-specific concerns, caregivers of children with DD reported a greater impact from the loss and/or delay of services and reported feeling significantly less capable of conducting educational activities in the home compared to caregivers of TD children. However, almost all caregivers in the study endorsed some level of stress from remote instruction. These findings suggest there is a specific need for attention to caregiver mental health and an examination of long-term educational outcomes resulting from extended school closures during the COVID-19 pandemic.