bluuebunny/crossref_metadata_2025 huggingface dataset:
Combinations of vitamin A and D induced are synergistic in breast cancer cells and alter gene expression in the endoplasmic reticulum stress, unfolded protein and estrogen signaling canonical pathways
Authors: Kanabar Pinal N. , Los Nina S. , Lawal Temitope O. , Patel Shitalben M. , Raut Nisikant A. , Maienschein-Cline Mark , Arbieva Zarema , Mahady Gail
Published: March 2023

Introduction: Numerous studies over the past 30 years have shown that bioactive compounds present in functional foods, including vitamins, minerals and phytochemicals reduce cancer risk. For example, vitamins A and D derivatives found in fruits, vegetables, and dairy products, reduce the growth of breast, bladder, head, neck, lung, prostate, and skin cancers. However, the effects of these combined vitamins have not been previously reported for breast cancer.Aims: To investigate the activities of vitamin A (all-trans-retinoic acid; ATRA), as well as vitamins D2 and D3 in combination in the breast epithelial cancer cell lines T47D:A18, MCF-7, and SK-BR-3 and perform whole genome analysis in MCF-7 cells using RNA-seq.Methods: Breast cancer cells were cultured in appropriate media and treated with ATRA, D2 or D3 alone in concentrations from 1-10 μg/ml, or in combination at 1, 5, and 10 μg/ml. The CellTiter-Glo® 2.0 assay, Caspase-Glo®3/7, Caspase®8, and ApoTox-Glo™ Triplex assays measured cell viability and apoptosis. The effect of treatment on autophagy in MCF-7 cells was measured with a CYTO-ID® Autophagy Detection Kit 2.0. The whole transcriptome analysis was assessed using mRNA-seq and qPCR.Results: Separately, ATRA, D2, and D3 all reduced the viability of all breast cancer cell lines tested, with median inhibitory concentrations (IC50) between 2.1 to 31.7 μg/ml. However, when breast cancer cells were treated with combinations of ATRA+D2+D3, the IC50 was reduced indicating synergism. In MCF-7 cells, 5-flurouracil (5-FLU) had an IC50 of 1.37 µg/ml, while the vitamin A and D combination had an IC50 of 1.5 µg/ml, indicating the combination was ~90% as effective as 5-FLU. Treatment of MCF-7 cells with ATRA+D2+D3 enhanced caspase 3/7 activity, as well as the expression of Bax, BAD, PTEN and p53 (apoptosis canonical pathway), as well as induced autophagy. Whole genome analysis of treated MCF-7 cells showed a significant upregulation in gene expression in the autophagy, endoplasmic reticulum stress and the unfolded protein response apoptosis canonical pathways. Furthermore, MCF-7 cells treated with ATRA+D2+D3 demonstrated significant downregulation of gene expression in estrogen-mediated S phase entry and estrogen signaling canonical pathways suggesting antiestrogenic effects. Conclusions: Vitamins A and D combinations had synergistic effects in breast cancer cells and induced both apoptosis and autophagy. Transcriptional profiling showed significant alterations in gene expression patterns and upregulation of multiple cancer signaling pathways supporting the hypothesis that combining vitamins A and D is a more effective treatment than either vitamin alone. Keywords: all-trans-retinoic acid (ATRA), Vitamin D2, Vitamin D3, breast cancer cells, apoptosis, estrogen receptors
Human Capital Development and Employee Job Satisfaction in Public Tertiary Institutions of Kogi State, Nigeria
Authors: Nafiu Akeem Tunde , Orga Sember Jennifer , Aduku Danlami Joseph
Published: March 2023

This study aimed at Human Capital Development and the job satisfaction of staff in public tertiary institutions in Kogi State. The sample size (126) was selected using multi-stage sampling technique. Descriptive statistics, Simple & Stepwise Multiple Regression and Pearson correlation matrix were employed for data analysis. Finding showed that perceived safety culture in the institution and access to medical facilities have strong influence on job satisfaction of staff in the Public Tertiary Institutions in Kogi State. The study concluded that investment in human capital development is a panacea for issues relative to job satisfaction; and that Public Tertiary Institutions in Kogi State must give attention to social safety and health care. This study recommended that the management of Public Tertiary Institutions should increase investment in human capital development so as to facilitate improved career advancement, and sustain its safety culture and improve on access to medical facilities; as these are crucial for increased job satisfaction of staff in the Public Tertiary Institutions in Kogi State.
Digital Transformation through the Prism of Digital Identity
Authors: Malik Tariq
Published: March 2023

Breakthroughs in digital technologies have notably enhanced the capability of administrative systems across the globe and allowed precision and effectiveness in governance mechanisms like never before. This study builds around three critical aspects of governance: lack of state capacity, trust deficit between citizen and state (empowerment), and poor service delivery. It elaborates how the use of biometrics and smart technologies enhances public service delivery and revitalises trust of citizen on the state. It is a qualitative research based on observations, case studies and real world examples of linking national citizens registry to various disparate repositories and using it innovatively to reform governance. Its manifestations are manifolds: from empowering persons to avail public health services and financial inclusion to creating value for private sector through market creating innovations; NADRA has fortified digital governance framework in Pakistan by the virtue of legal identity. The success story of NADRA provides guidelines to the developing countries how organisations can be turned around by employing technologically innovative and culturally targeted approach towards public policy and digital governance initiatives.

Keywords: Digital Transformation, e-Governance, Technology, Legal Identity
Avanços na nutrição de bovinos leiteiros – uma revisão sobre os macrominerais
Authors:   Universidade Federal de Santa Maria, Moraes Matheus Lehnhart de , Costa Franciely Alves ,   Universidade Federal de Jataí
Published: March 2023

Mineral nutrition for dairy cattle has advanced considerably in recent decades. The requirements, as well as the entire metabolism of each mineral element, have been demystified by science, attributing accuracy in the predictions of liquid requirements. These advances also allow us to understand the factors that influence absorption, metabolism and their impact on the animal's organism. Among the mineral elements, the macroelements represent the highest cost in the formulation of supplements and/or mineral cores, and often the excessive supplementation of these can cause serious damage to the cows, in addition to contamination of the environment. In this context, this review summarizes the main advances in mineral macroelements nutrition for dairy cattle, as well as their requirements, main sources, functions, absorption, excess and interactions with other mineral elements.
Debt-Based Economy: A Reappraisal of Prosperity and Crisis
Authors: Furqani Hafas , Fuad Zaki , Idul Adha Syamsul , Awalurramadhana Awalurramadhana
Published: March 2023

Debt and economic activity seem to be inseparable. Debt in a society is considered as something normal in economic activities to meet various needs. The government of a country also needs external debt to overcome the problem of budget deficit in addition to providing a greater stimulus to domestic economic growth. Debt has eventually become a lifestyle and is considered as a profitable business. Therefore, credit facilities have been innovated from a simple form aimed at assisting those in need into a sophisticated financial product aimed at commercialization and profit through financial engineering. In Islamic perspective, debt is allowed within certain Shari’ah and ethical parameters. It is acknowledged that debt have both advantages and disadvantages in the economy. Debt is viewed as both a driver of prosperity and a source of economic crisis. Therefore, this paper recommends that taking debts should be in line with the ability to repay, good management and use of debt for the right purpose. In addition, debt should be made transparent to the public in order to create senses of responsibility, instituting regulating framework of supervision, and embedding it in macroeconomic policies to stimulate growth and enhance welfare.
Design and simulation of a new self–adaptive MR damper for washing machines featuring shear–mode and radial permanent magnets
Authors:   Faculty of Civil Engineering, HCMC University of Technology and Education, Ho Chi Minh City, Vietnam, Bui Quoc–Duy ,   Faculty of Mechanical Engineering, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam, Nguyen Quoc Hung ,   Faculty of Engineering, Vietnamese–German University, Thu Dau Mot City, Binh Duong Province, Vietnam
Published: March 2023

This research investigates a new magneto–rheological (MR) damper for washing machines which can effectively replace conventional passive dampers in the field of vibration control. Against traditional MR dampers and self–powered ones, the new damper is extremely cost–effective for commercialization coming from its compact structure and self–adaptive ability to external mechanical vibration for reasonable damping without any equipment or control. By adding a layer of MR fluid (MRF) between the damper shaft and housing, the damping coefficient can be adjusted according to applied magnetic field intensity. Radial ring permanent magnets are installed on the housing and the middle shaft part is made of non–magnetic material for the inactive state of the damper. Under great vibration of washing machines, the magnetic shaft parts move into the region of MRF and magnets, which generates closed magnetic circuits. Subjected to applied magnetic fields, the MRF undergoes a transition from free flowing to semi solid, thereby experiences increases in its rheological characteristics such as yield stress and viscosity. The relative movement between the shearing shaft and the MRF in the gap is then resisted and additional damping force is produced. The higher the oscillatory amplitude is the more magnetic shaft parts contact the MRF, which results in stronger induced magnetic fields and a larger damping force to suppress the oscillation. This displacement–based damping characteristic is especially proper for vibration suppression of washing machines. In order to enhance oscillation isolation efficiency and at the same time meet criteria of assembly space, size and cost, optimization is performed for essential geometrical dimensions of the proposed damper. Then, the advantages in performance characteristics of the proposed damper are figured out from the optimization results with discussions.
Optimal location and impacts of 1 MWP solar pv plants on distribution network protection
Authors:   Faculty of Electrical and Electronics Engineering, Ho Chi Minh City University of Technology, VNU-HCM, Vietnam, Dang Khanh Tuan , Tran Huy Hoan ,   Faculty of Electrical and Electronics Engineering, Ho Chi Minh City University of Technology, VNU-HCM, Vietnam, Truong Hoang Bao Huy ,   Institute of Engineering and Technology, Thu Dau Mot University, Vietnam
Published: March 2023

Nowadays, the penetration of the distributed energy resources into the power distribution network is increasing, especially the 1 MWp solar PV plants since they have been enjoying the Feed-in tariff scheme. In order to reduce the losses of the distribution power network efficiently, this paper uses the Symbiotic Organism Search (SOS) algorithm to determine the optimal location for these solar power sources. However, when these distributed power sources are connected to the distribution network, they can cause to lose the selective coordination between reclosers and fuses - the main protection devices of the distribution network. The prominent feature of this report is to be based on the availability of reclosers, fuses, and with consideration of the Khc coefficient (which is affected by the time and number of reclose attempts). Hence, a simple but efficient solution is proposed to ensure selective recloser – fuse coordination. The mentioned SOS algorithm and the solution are to be applied to the 473TH 22 kV distribution network in Tay Ninh province. The simulation results using Matlab and Etap indicate that the SOS algorithm along with the proposed solution are beneficial to planning and locating distributed power sources, and simultaneously help to overcome the non-selective recloser – fuse coordination.
Design of low cost-remote eye tracker using Pupil Center-Corneal Reflection technique
Authors:   Department of Biomedical Engineering, the Faculty of Applied Science, Ho Chi Minh City University of Technology, VNU-HCM, Vietnam, Do Phu Tuong , Huynh Linh Quang ,   Department of Biomedical Engineering, the Faculty of Applied Science, Ho Chi Minh City University of Technology, VNU-HCM, Vietnam, Le Dang Cao ,   Department of Biomedical Engineering, the Faculty of Applied Science, Ho Chi Minh City University of Technology, VNU-HCM, Vietnam, Tran Tin Trung ,   Department of Biomedical Engineering, the Faculty of Applied Science, Ho Chi Minh City University of Technology, VNU-HCM, Vietnam
Published: March 2023

The eye tracker is used in many fields such as education, marketing, psychology, medicine, among others. However, commercial devices are costly, spanning from a few hundred to several thousand dollars. Therefore, an inexpensive-monocular-remote (IMR) eye tracker is developed for education and research, which implements the Pupil-Center-Corneal-Reflection technique. The IMR device consists of a low-cost camera with a near-IR pass filter that captures subject’s eye images, a moderate-cost computer that processes these images, as well as two near-IR light sources that create glints and illuminate the eye. The pupil detection algorithm is developed by combining the advantages of two recent algorithms, named BORE and PDIF, and gaze points are estimated from pupil-glints vectors via a fourth-order polynomial. An experimental evaluation is conducted concurrently on the research eye tracker IMR at the operating frequency of 30 Hz and the commercial-high-end-head-free device VT3 Mini at 60 Hz, in a challenge condition: subjects sit down near a window, and some of them wear glasses. Also, their heads are placed on a fixed chin rest, and the data is acquired when both devices successfully estimate gaze points. The experimental results in 11 sample data, obtained from 7 subjects, show that the overall ratio of the number of filtered/raw samples and raw/idea samples are 88.92% and 98.63% in order. Whereas the overall precision of the IMR eye tracker is nearly equal to that of the VT3 Mini device (0.57 degrees and 0.54 degrees, respectively), the overall accuracy of the proposed eye tracker is better than that of the commercial device (1.04 degrees and 1.34 degrees, respectively). Regarding eye safety, the radiant power and the burn-hazard-weighted radiance of the proposed device are much smaller than their limitations, according to IEC 62471. With these results, the IMR eye tracker is appropriate for education and needs to be improved in terms of data validation to satisfy the research purpose.
Controllers design for the semi-automation shrimps tempura frying production line
Authors:   Faculty of Mechanical Engineering, Ho Chi Minh City University of Technology, VNUHCM, Vietnam, Vo Trung Chanh , Vu Thanh Cong Tran ,   Bach Khoa Research Center for Manufacturing Engineering, Ho Chi Minh City University of Technology, VNUHCM, Vietnam, Vuong Quan Tuan ,   Faculty of Mechanical Engineering, Ho Chi Minh City University of Technology, VNUHCM, Vietnam, Phan Minh Quang , Nguyen Dat Tan ,   Faculty of Mechanical Engineering, Ho Chi Minh City University of Technology, VNUHCM, Vietnam, Le Long Quang ,   Faculty of Mechanical Engineering, Ho Chi Minh City University of Technology, VNUHCM, Vietnam, Vo Tuong Quan ,   aculty of Mechanical Engineering, Ho Chi Minh City University of Technology, VNUHCM, Vietnam
Published: March 2023

Nowadays, the applications of automatic control systems have been developing very fast in many diversify of the industry fields. One of the most significant industry that is needed to care and focus to develop this automation technology in order to reduce the huge number of workers and increase the productivity is the seafood industries. Normally, the seafood industry has a lot of workers to carry out everything manually. There still remain many research topics relating to this field to help this industry to develop in the trend of 4.0 ages. The semi–automation shrimps Tempura frying production line is a system to make Tempura shrimps with high productivity. The workers simply put the shrimps into the serial of chain frying molds and the system will automatically do the whole production process to produce the completed Tempura shrimps. The whole process to produce Tempura shrimps includes the following steps: (1) Shaping shrimp and cover with powder solution by automatic powder solution spraying system; (2) Complete frying to make the shrimps to be cooked; (3) Oil draining system to remove the remain oil inside the shrimp and the powder cover. Then the finished products will be put into the frozen system to preserve. The whole production line will be separated into 3 main modules: Module 1: The shaping module (first time frying) and powder solution spraying module; Module 2: The deep fry module (second time frying); Module 3: The oil draining module. This paper introduces about the control system for each module and the controller of the whole system to make a complete semi-automation shrimp tempura frying production line. Some controller technology as On/Off, PID control algorithms are proposed to apply for the whole production line as: speed control of the stainless-steel chain conveyors, temperature control of the cooked tanks, quantitative control of the powder solution amount to be sprayed on the shrimps, the oil draining conveyor speed, the heat and air flow control of the oil draining module.
An analysis of turning stability dynamics of TERA 240 truck by the four - Wheeled planar vehicle dynamic model
Authors:   Ho Chi Minh City University of Technology (HCMUT)– VNU-HCM, Vietnam, Tran Hoang Y , Tran Huu Nhan ,   Ho Chi Minh City University of Technology (HCMUT)– VNU-HCM, Vietnam, Tran Quang Lam ,   Ho Chi Minh City University of Technology (HCMUT)– VNU-HCM, Vietnam, Pham Ngoc Dai ,   Ho Chi Minh City University of Technology (HCMUT)– VNU-HCM, Vietnam
Published: March 2023

The turning dynamic features to ensure stable and safe conditions of the TERA 240 truck are investigated using the four-wheeled planar dynamic model, in which the force components from 4 wheels are taken into account to build a computational model with the time-varying steering angle is used. The necessary input parameters of the TERA 240 vehicle for the vehicle planar dynamic model are determined on the basis of the available actual vehicle, with all 3 loading cases are noload, half-load and full-load. The kinematic and dynamic parameters describing the vehicle's planar turning motion are determined, resulting in the basement for evaluating the vehicle's motion stability. The calculation process is performed in the velocity domain to ensure the ultimate stability condition that the vehicle does not slide or overturn when turning. The obtained results are analyzed to evaluate the vehicle's turning stability performance, based on the variable relationship of the parameters in the investigated cases: turning radius is constant, velocity is constant, and steering angle is constant. The vehicle's turning stability is specifically defined: the vehicle is understeer with no-load case, the vehicle is oversteer with half-load and full-load cases.
Applying 3D geological model for oil initially in place estimation Dong Duong oilfield, Block 02/97, Cuu Long basin
Authors:   Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam, Nguyễn Tuấn ,   Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City,Vietnam, Trần Văn Xuân ,   Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam; Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City,Vietnam, Nguyễn Xuân Khá ,   Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam; Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City,Vietnam, Trương Quốc Thanh ,   Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam; Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City,Vietnam, Trần Đức Lân ,   Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam; Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City,Vietnam
Published: March 2023

Despite the crisis, oil and gas is still an irreplaceable energy resource. However, it is a non-renewable resource, so in addition to expanding the search, the rational exploitation of the existing fields is a challenge for the oilfield exploration and production. Combining methods including collecting, processing and analyzing existing documents and data; the results of the article have determined the workflow of building a parametric model suitable for the research object and applying geostatistics simutaneously to interpolate geological features as well as assess reliability and reduce risks. In this study, a three-dimensional (3D) geological model is established according to updated datas, including geological, seismic, well log, well testing, and using as the data base for oil initially in place estimation. Specially, effectively supported establishing economic and technical plans for field development. The model results have clarified the reservoir parameters in Miocene formation, predicting potential reservoirs; expression the characteristics of reservoir distribution in 3D space. The 3D geological model of Dong Duong oilfield with a cycle is established on the basis application of geostatistical methods, stochastic simulation and is applied to describe the homogeneity of the reservoir as well as build up parameter models. The process of checking the accuracy of the model is conducted by comparing the data from the model and the input data: seismic, geological, reserve apprisal report,... illustrates that there is no difference any deviation beyond the allowable limit.
Assessment of groundwater resources management capacity in Tra Vinh Provine by sustainable indicators
Authors:   Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam, Đào Hồng Hải ,   Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam, Nguyễn Việt Kỳ ,   Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam; Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam
Published: March 2023

Tra Vinh province is one of the coastal provinces in the Mekong Delta, which is greatly influenced by the tidal regime of the sea and main rivers such as the Tien and Hau rivers. In addition, surface water resources are increasingly contaminated with salt and polluted due to natural conditions and human economic activities. In addition, groundwater resources have played a major role in providing fresh water for daily life and the people's economic activities. However, with complex hydrogeological characteristics (distribution of pale surface between aquifers) that has made the design of exploitation well systems not synchronized, the awareness of the use of water resources of the country has not been achieved. The population is not high, leading to an unreasonable arrangement of exploitation wells between aquifers and between areas, causing the water level in the province to decrease, salinization in exploitation wells. increasingly widespread. All these factors can be seen that this resource is being managed and used unsustainably, so the research team wants to synthesize data on exploitation, monitoring, use, and policies. policies, planning, management organization, and the level of knowledge of people in the area to comprehensively assess the sustainability of groundwater resources. Research results show that there is a difference in the number of assessment scores in Tra Vinh province that reflect the level of socio-economic development of each area. Based on the selected set of criteria, the research team has assessed that the level of management of groundwater resources in Tra Vinh province is "highly sustainable" through 5 evaluation criteria of the sustainability index: (1) “Pressure on groundwater resources” average score of 41.9/60; (2) "Knowledge management" assessment scores in the whole province, the score in this criterion is quite high, the average score is 41.4/50; (3) “Policies & Laws” index average score is 28.4/30; (4) “Stakeholder involvement” Average score is 26/40; (5) “Organization & Capacity” average score is 30/40. The results of this study will help managers have an overview of the picture of groundwater in the province, thereby taking zoning measures, more reasonable exploitation planning, and people. It will also raise awareness of the use of water resources in scarce areas.
Main directions in the study of infants’ growth at Moscow school of anthropology: а review based on the articles published in «Moscow University Anthropology Bulletin (MUAB)» for the last 15 years
Authors:   Lomonosov Moscow State University, Anuchin Research Institute and Museum of Anthropology, Mokhovaya st., 11, Moscow, 125009, Russia, Permiakova Ekaterina Yurievna
Published: March 2023

Introduction. The present study is of a complex nature and is devoted to the assessment of the main directions of the development of auxology in Russian anthropology. To a large extent, this work is a continuation of the review of the activities of the laboratory of auxology of the Anuchin Research Institute and the Museum of Anthropology of Moscow State University [Godina, 2010]. At the same time, the main directions of work are considered and described in more detail not only directly by the auxology laboratory, but also by other working groups of the same Institute, the Department of Anthropology of the Faculty of Biology of Lomonosov Moscow State University, as well as other academic institutions. Materials and methods. Specifically, in this part of the work, articles devoted to the comprehensive assessment of the processes of growth and development of children from birth to 3 years old, which were published in the «Moscow University Anthropology Bulletin» from 2009 to 2022, were used as a source of information. Results and discussion. The studies conducted in this area affect a large number of aspects of physical development in infancy and early childhood – for example, factors influencing these processes (evolutionary, climatic, geographical, ethnic and genetic factors, constitutional features of mothers, circumstances of intrauterine growth) are analyzed on representative samples. Special attention should be paid to the work on the evaluation in comparative and secular aspects of growth processes and indicators of sexual dimorphism of children under 3 years of age in the countries of the former USSR. Conclusion. Despite the difficulties in working with a rather specific contingent, the fact that these works, together with the results obtained, lead us to conclude that this stage of ontogenesis is represented to a large extent in the works of domestic anthropologists, which allows us to use these data both in the field of interdisciplinary and interdepartmental research.
To the problem of morphofunctional status of schoolchildren of Nizhny Novgorod region in connection with ecological factors
Authors:   Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, Minin and Pozharsky sq., 10/1, Nizhny Novgorod, 603005, Russia, Kalyuzhny Evgeny A. , Gorbacheva Anna K. ,   Lomonosov Moscow State University, Anuchin Research Institute and Museum of Anthropology, Mokhovaya st., 11, Moscow, 125009, Russia, Fedotova Tatiana K. ,   Lomonosov Moscow State University, Anuchin Research Institute and Museum of Anthropology, Mokhovaya st., 11, Moscow, 125009, Russia
Published: March 2023

Introduction. Morphofunctional (MF) status of school children of Nizhny Novgorod region is analysed in connection with the degree of urbanization and the level of anthropogenic pressure in contrastive ecological clusters with satisfactory (1), comparatively tense (2), tense (3) and critical ecological situation. Material and methods. Over 5 thousand of school children aged 7–17 years, examined in 2010–12, are under discussion. The program includes height, weight, BMI, chest girth, lung vital capacity (VC), systolic and diastolic blood pressure, somatotype according to Shtefko-Ostrovskiy method. Each cluster is characterized by absolute and standardized values of MF indices; significance of differences between means of parameters with continuous variability for separate ecological groups is estimated by using of analysis of variance and Scheffe-tests. Frequency of somatotypes (%) is calculated for each ecological group, Pearson's chi-square criterion is used. Comparative estimation of total somatic dimensions of rural and urban (literary data) children is held. Results. The accelerating influence of modern level of anthropogenic stress (clusters 2 and 3) on indices of transversal body development (weight, BMI, chest girth) and VC of prepubertal (9 years) children irrespective of sex is shown. Decelerating influence of critical stress level (cluster 4) on indices of transversal body development of pubertal children aged 13 years is revealed. No significant differences in frequency of somatotypes in contrastive ecological clusters are fixed. Some gracilization of urban prepubertal boys compared to rural boys is shown. Some macrosomization (height and weight) of urban girls aged 7–13 years combined with modest decrease of chest girth as compared to rural girls is fixed. Up to 16–17 years all described differences are obviously smoothed. Conclusion. The effect of anthropoecological correlations depends on the level of anthropogenic stress, sex and age of examined population and the system of MF indices. Height in our case is less sensitive to the increase of the level of anthropogenic stress. Ecosensitivity of girls is presumably less than boys.
Prevalence and characteristics of radiographic hand osteoarthritis in rural Turkmens
Authors:   Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, 84105, P.O.B. 653, Israel, Kalichman Leonid , Batsevich Valery ,   Lomonosov Moscow State University, Anuchin Institute and Museum of Anthropology, Mokhovaya st., 11, Moscow, 125009, Russia, Kobyliansky Eugene ,   Department of Anatomy and Anthropology; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, P.O.B. 39040, Israel
Published: March 2023

Introduction. The knowledge about the prevalence of hand osteoarthritis (OA) in different populations, the pattern of joint involvement, and the association with age, sex, and weight might be helpful in the understanding of the etiology and in developing the prevention strategy of hand OA. It can be important from a public health perspective. The study aimed to evaluate the prevalence and pattern of radiographic hand OA in the Turkmen community-based sample and its association with age, sex, and body mass index. Materials and methods. The study population was comprised of Turkmens (277 males and 427 females, aged 19–90 years). Radiographic hand OA was evaluated for 14 joints of each hand according to the Kellgren and Lawrence grading scheme. Statistical analyses included prevalence estimation, linear regression, and χ2 tests. Results. 13.8% of individuals before age 36 had at least one joint with OA, and the prevalence reached 100% after age 65. After adjustment for age, we found that females with severe obesity have a higher risk of development of radiographic hand OA than those with normal weight (OR(95%CI): 3.88 (1.20-12.60)). Conclusion. In the present study, after adjusting for age, we found that in men there was no association between the prevalence of hand OA and BMI. However, women with severe obesity are almost four times more likely to develop hand OA than women of normal weight.
Nonlinear relationship between motor skills and BMI in the group of school-age boys of 7–12 years
Authors:   Lomonosov Moscow State University, Anuchin Research Institute and Museum of Anthropology, Mokhovaya st., 11, Moscow, 125009, Russia, Parfenteva Olga Ivanovna , Sonkin Valentin Dmitrievich ,   Institute of Developmental Physiology Russian Academy of Education, Pogodynskaya st, 8/2, Moscow, 119121, Russia
Published: March 2023

Introduction. Childhood and adolescent obesity are associated with impairment of motor skills. However, studies assessing effect of underweight on motor skills as well as the relationship between body mass index (BMI) and motor skills are limited. The purpose of the study was to evaluate relationship between motor skills and BMI in the group of school-aged boys (7–12 years). Material and methods. The data were collected from 7–12-year-old boys (1–5th grade) in the 38 Russia's federal constituent entities of eight federal districts. Height and weight were measured, BMI was calculated. Physical education teachers conducted the testing: endurance 6-minute run test (meters), 3x10 m shuttle run test (seconds), long standing jump (centimeters), forward bend test (centimeters), and 30-m sprint run test (seconds). The dataset contained 54 381 observations. The linear, quadratic and general additive models were built to check relationships between the motor skills and BMI. Results. It was identified that high values of BMI are associated with impaired results of endurance and speed-strength abilities. Male children with a low and normal BMI values did not differ in motor skills. Despite a low level of explained variation of proportion of motor skills, a significant relationship between of motor development and BMI are noted. In the group of 7-year-old male children, the relationship was not identified. Whereas in the group of 8–12-year-old children it has a curvilinear relationship. Conclusion. The relationship between motor skills and BMI is curvilinear (quadratic) in the group of 8–12-year-old boys. Hereafter, the modeling of non-linear relationship between motor development and BMI with other predictors might help identifying the optimum zone of body composition where the adaptation potential will be the highest. It is also allowed to compare this zone in the groups of different ages and sexes.
Diet according to multidisciplinary studies: steppes and forest steppes of the Volga region and Southern Ural in the Bronze Age
Authors:   Lomonosov Moscow State University, Anuchin Research Institute and Museum of Anthropology, Mokhovaya st., 11, Moscow, 125009, Russia, Karapetian Marina K.
Published: March 2023

Introduction. As a part of paleopathological studies of people inhabiting the Volga-Ural and Southern Ural steppes and forest-steppes in the Bronze Age, it became necessary to study and generalize the available extensive data on diet of this population provided by specialists from various related fields. Indeed, the state of “health” is largely related to what and how a person eats and under what pathogenic burden he lives. Materials and methods. The paper summarizes main results of archaeological, zooarchaeological, paleobotanical, geochemical, isotope and paleopathological studies. Results. It has been almost reliably established that animal husbandry was the economic basis of the studied population with elements of hunting and gathering and the absence of crop cultivation. Zooarchaeological studies show that cattle played dominant role and were used both for meat and milk, with some territorial and temporal variations in which of these components was more important. Hunting and fishing played, apparently, a secondary role. It is obvious that the use of plant foods did take place. Researchers agree that the studied population consumed wild plants growing in the steppes and forest-steppes, such as Chenopodium, Amaranthus and a number of others. Conclusion. Studies of associated disciplines are in many ways interrelated and mutually interpretable, which allows us to create a general picture. At the same time, a number of unresolved issues remain that require further, more detailed analytical developments, including those involving paleopathological data.
Forensic facial reconstruction of a man from the Shamakhigrave field of the early medieval period
Authors:   Biological Sciences Dep., Khazar University, Ibrahimov Anar Sh. ,   Baku, Meskheti str., 41, Baku, AZ1096, Azerbaijan, Yevseyev Roman V. ,   «Other worlds studio», Nagornaya st., 36, Moscow, 117186, Russia, Aliev Akper A. ,   Azerbaijan DNA Project, FTDNALab., 1445 N Loop W Fwy, Ste 820, Houston, TX 77008, USA
Published: March 2023

Introduction. Until now, no work has been carried out to reconstruct the external appearance of the ancient population of Transcaucasia. In order to fill this gap, this study of the skull of a man from an early medieval catacomb burial in the Shamakhi region of Azerbaijan was undertaken. Craniometric and odontometric measurements determined the sex, racial type, age at death, revealed pathologies of the dentition and various traumatic injuries. The purpose of the work was to obtain primary information about the appearance of people who lived in the first centuries of our era on the territory of Azerbaijan and thereby attract scientific attention to this problem. Materials and methods. The skull, found in 1949 by the expedition of R.M. Kasimova with the participation of G.F. Debets, underwent an anthropological study according to classical programs to determine age, gender and race. Lifetime appearance restoration in the form of a graphic portrait in isometric projection was carried out according to the method of M.M. Gerasimov and E.V. Veselovskaya using Adobe Photoshop CC 2020 graphics editor. Results. A table of individual measurements of the skull is presented, lifetime dimensions of the head are calculated, and a verbal description of the appearance is given. In racial terms, the subject can be attributed to the Caspian subtype of the Indo-Mediterranean race, the most characteristic modern representatives of which are Azerbaijanis, which also illustrates the reconstructed graphic appearance. Discussion. The metric data of the skull were compared with similar characteristics of the closest male samples, which included a total of over 1300 skulls from the Caucasus, Central Asia, and Southwestern Europe. Based on the results of applying the corresponding discriminant analysis equations, it was found that the studied skull in the racial format belongs to the Caspian anthropological type. Conclusion. As a result of the reconstruction of the appearance of the skull of a man from the early medieval burial ground in the Shamakhi region of Azerbaijan, paleoanthropological material unique for the Transcaucasian region was obtained for the first time. Previous archaeogenetic studies confirmed its belonging to the local population of Transcaucasia.
Efektivitas Intrument D-Cacth sebagai Alat Ukur Dokumentasi Keperawatan: Scoping Review
Authors: Susanto Deni , Muliantika Muliantika , Kurniawan Kurniawan
Published: March 2023

Dokumentasi keperawatan merupakan salah satu aspek penting yang menunjang proses keperawatan, maka perlu adanya audit dokumentasi yang tepat dalam mengukur kualitas dokumen tersebut. D-Cacth merupakan salah satu inovasi dalam bentuk instrumen yang diharapkan mampu mengaudit dokumen keperawatan. Tujuan dari review ini adalah untuk mengetahui keakuratan dari instrumen D-Cacth dalam mengukur kualitas dokumentasi keperawatan. Metode yang digunakan adalah scoping review yang terdiri dari 5 tahap yaitu: mengidentifikasi pertanyaan penelitian, mengidentifikasi sumber yang relevan yaitu mencari artikel dibeberapa database seperti ProQuest, ScienceDirect dan Google Scholar dengan menggunakan framework PICO, melakukan seleksi literatur yang digambarkan melalui diagram PRISMA, melakukan pemetaan dan mengumpulkan literatur serta menyusun dan melaporkan hasil. Hasil Penelusuran artikel diperoleh 3 artikel yang relevan dan sesuai dengan topik yang dibahas. Hasil tinjauan literature menunjukkan bahwa instrument D-Cacth telah terbukti mampu secara akurat dalam mengukur kualitas dan kuantitas dokumentasi keperawatan.
Intervensi untuk Meningkatkan Kesejahteraan Spiritual pada Pasien Dewasa dengan Kanker: A Scoping Review
Authors: Widianti Efri , Hikmat Rohman , Pasya Shofura Kamil , Hanifah Salma , Hidayati Nur Oktavia
Published: March 2023

Kanker mengancam makna hidup pasien yang terkadang mengarah pada munculnya rasa disintegrasi. Disintegrasi muncul akibat permasalahan distress spiritual sehingga menunjukkan perlunya pemenuhan kebutuhan spiritual. Mengatasi kebutuhan spiritual pasien kanker penting dalam mempercepat pemulihan dan mencapai kesejahteraan spiritual. Tujuan untuk mengeksplorasi intervensi yang dapat dilakukan dalam meningkatkan kesejahteraan spiritual pada pasien kanker. Studi ini menggunakan desain scoping review. Pencarian artikel dari 2 database PubMed dan EBSCOHost serta 1 search engine yaitu Google Scholar dengan waktu publikasi pada 5 tahun terakhir (2018 – 2022) berdasarkan kata kunci “Intervention” AND “Spiritual Well-being” AND “Patient Cancer”. Hasilnya sebanyak 9 artikel diperoleh dan dianalisis dengan analisis tematik. Berdasarkan hasil tinjauan literatur pada 9 artikel, ditemukan 6 intervensi spiritual yaitu spiritual therapy, spiritual group therapy, mindfulness, spiritual counseling, meditation, dan islami-based caring. Intervensi-intervensi tersebut terbukti dapat meningkatkan kesejahteraan spiritual pada pasien kanker.
Manajemen Pengelolaan Linen di Instalasi Laundry Rumah Sakit di Indonesia
Authors: Ningsih Sari , Sriatmi Ayun , Suhartono
Published: March 2023

Linen merupakan istilah yang mengacu pada semua tekstil yang ada di rumah sakit, seperti linen ruang rawat dan ruang bedah operasi. Peran manajemen linen di rumah sakit sangat penting. Dalam penelitian ini peneliti bermaksud untuk melakukan suatu kajian yang intensif pada beberapa penelitian terdahulu guna mengetahui bagaimana manajemen linen di instalasi laundry rumah sakit yang ada di Indonesia serta kendala apa saja yang menyebabkan tata kelola linen belum maksimal yang akan ditinjau dari berbagai aspek. Penulisan dalam penelitian ini menggunakan pendekatan metode literature review, berdasarkan kriteria inklusi, artikel yang memenuhi kriteria ada sebanyak 17 artikel yang terdiri dari: PubMed 6 artikel,  Scopus 1 artikel, Spinger Link 2 artikel, JSTOR  4 artikel dan Undip E-jurnal 2 artikel, yang diterbitkan pada tahun 2015 sampai dengan tahun 2022. Penanganan linen di berbagai rumah sakit di Indonesia umumnya masih kurang optimal dan tidak sesuai dengan standar yang ditetapkan. Dilihat dari aspek masukan sarana prasarana yang masih kurang memadai, dari segi SDM kualitas dan kuantitas masih kurang, penerapan SOP yang belum terlaksana dengan baik masih ada petugas yang tidak menggunakan APD saat melakukan kegiatan pengelolaan linen. Dari aspek proses terlihat perbedaan dari setiap rumah sakit di Indonesia mulai dari tahapan perencanaan, pelaksanaan yang meliputi; pemisahan, pengangkutan, pencucian dan penyimpanan hingga pada penditribusian sampai pada pengendalian. Kurang optimalnya aspek masukan dan proses menyebabkan pemberian pelayanan terkait linen kurang maksimal, hal ini dapat mempengaruhi mutu pelayanan yang diberikan oleh pihak rumah sakit serta berdampak pada kepuasan pasien.
Analisis Hubungan Kepadatan Penduduk dengan Kejadian Demam Berdarah Dengue (DBD) di Provinsi Jawa Barat
Authors: Ayuningtyas Alifiah
Published: March 2023

Demam Berdarah Dengue (DBD) merupakan salah satu permasalahan kesehatan yang perlu mendapat perhatian lebih di Indonesia, bahkan dunia. Provinsi Jawa Barat merupakan provinsi dengan jumlah kasus DBD tertinggi di Indonesia pada Tahun 2021. Provinsi ini memiliki kepadatan penduduk yang tergolong tinggi, yang mana merupakan salah satu faktor risiko dari kejadian DBD. Penelitian ini bertujuan untuk menganalisis hubungan antara kepadatan penduduk dengan kejadian Demam Berdarah Dengue (DBD) di Provinsi Jawa Barat Tahun 2021. Penelitian ini termasuk penelitian observasional analitik dengan desain cross-sectional yang menggunakan data sekunder. Uji yang dilakukan adalah uji korelasi spearman untuk mengetahui hubungan di antara kedua variabel. Dari hasil uji Shapiro-Wilk, diketahui bahwa data penelitian tidak berdistribusi normal (p value=0,000). Sedangkan hasil uji korelasi spearman, menunjukkan bahwa p value sebesar 0,020 (p value < 0,05) dan koefisien relasi sebesar 0,446. Hal ini dapat disimpulkan bahwa terdapat hubungan antara kepadatan penduduk dengan kejadian DBD di Provinsi Jawa Barat. Hubungan tersebut memiliki arah positif dengan kekuatan hubungan yang cukup kuat.
Peningkatan Motivasi Kerja Tenaga Kesehatan dengan Administrasi Rumah Sakit: Meta-Analisis
Authors: Zamani Ahmad , Rokhmatun Puji Nur , Maesaroh Siti , Widiyanto Aris , Atmojo Joko Tri
Published: March 2023

Penelitian systematic review dan meta-analysis ini bertujuan untuk memperkirakan hubungan antara administrasi rumah sakit terhadap peningkatan motivasi kerja pada tenaga kesehatan. Sebanyak 10 artikel dipilih untuk dilakukan meta-analisis. Penelitian ini menggunakan akronim PICO. Population: tenaga kesehatan; Intervention: administrasi rumah sakit yang baik; Comparison: administrasi rumah sakit yang buruk; Outcome: motivasi kerja. Data diperoleh dari database diantaranya yaitu PubMed, Springer Link, Science direct, dan Google Scholar. Data dianalisis menggunakan RevMan 5.3. Terdapat 10 artikel menggunakan desain penelitian cross-sectional dengan total sampel 3,282 subjek dari Indonesia, Turki, Ghana, Uganda, Myanmar, dan Ethiopia yang telah dilakukan tinjauan sistematis dan meta-analisis. Hasil penelitian menunjukkan bahwa tenaga kesehatan yang bekerja di rumah sakit dengan administrasi yang baik akan meningkatkan motivasi kerja sebesar 2.50 kali dibandingkan dengan tenaga kesehatan yang bekerja di rumah sakit dengan administrasi yang buruk (aOR= 2.50; CI 95%= 2.01 hingga 3.11; p< 0.001).
Efektivitas Peanut Ball terhadap Penurunan Nyeri Persalinan
Authors: Darma Ika Yulia , Indriani Silfina , Handayani Riri Yulia , Zaimy Silvi , Idaman Meldafia
Published: March 2023

Nyeri persalinan yang tidak diatasi dengan baik akan menyebabkan kecemasan dan stress pada ibu bersalin, sehingga dapat mengakibatkan patus lama dan komplikasi persalinan lainnya. Salah satu teknik relaksasi dan tindakan nonfarmakologis dalam penanganan nyeri saat persalinan dengan menggunakan peanut ball. Tujuan penelitian untuk mengetahui efektivitas peanut ball terhadap penurunan nyeri persalinan pada kala I. Jenis penelitian quasy experiment dengan one group pretest and posttest design, dilakukan pada bulan November 2022 sampai Januari 2023 di Bidan Praktik Mandiri Kota Padang. Sampel berjumlah 15 orang ibu bersalin kala I yang memenuhi kriteri inklusi penelitian yang diperoleh dengan teknik purposive sampling. Data di peroleh menggunakan lembar observasi dan SOP VAS. Data dianalisa menggunakan uji dependent sampel t  test.  Rerata nyeri persalinan sebelum diberikan peanut ball 5,47±0,639. Rerata nyeri persalinan setelah diberikan peanut ball 4,67 ± 1,099. Rerata penurunan nyeri persalinan 1,40 ± 0, 986.  Berdasarkan uji paired t test diperoleh signifikansi sebesar 0,000 ( p value < 0,05). Terdapat efektivitas Peanut ball  terhadap penurunan nyeri persalinan di Bidan Praktik Mandiri Kota Padang.