bluuebunny/crossref_metadata_2025 huggingface dataset:
RECEITAS E DESPESAS GOVERNAMENTAIS PARAENSE: UMA ANÁLISE DE CAUSALIDADE, EFEITOS DE CURTO E LONGO PRAZO
Authors: Simões Jorge Eduardo Macedo , Dos Santos Edglan Albuquerque
Published: July 2022

O presente estudo analisa o desempenho das contas públicas do estado do Pará, mais precisamente a relação entre arrecadação e gastos públicos, buscando fornecer evidências empíricas da relação causal entre receitas e despesas governamentais, ou seja, se os aumentos da arrecadação são oriundos de elevação de despesas, ou essa causalidade é reversa. Além disso, através das técnicas de cointegração, tal como descrito por Johansen (1988) e modelo de correção de erros, conforme (Johansen e Juselius, 1990), para o período entre janeiro de 2003 e agosto de 2019, são estimados os efeitos de curto e longo prazo. Os resultados evidenciam, que o estado do Pará se enquadra na hipótese levantada por Friedman (1987), tax-and-spend (arrecadar e gastar). Isso significa que a medida mais adequada para enxugar a expansão dos gastos governamentais seria os cortes permanentes de impostos.
“... É BEM ULTRAPASSADO ISSO AQUI NA VERDADE”: JOVENS SECUNDARISTAS E SUAS CONCEPÇÕES DE GÊNERO
Authors: CASTRO Roney Polato de , COURA Ana Carolina Mercês
Published: July 2022

The article discusses the conceptions of high school students from a public school in the interior of Minas Gerais about gender relations. The discussion is based on data from a master’s degree research in education, whose objective was to build spaces for narrative production with these young people, focusing on their conceptions and ways of living and thinking about gender, sexuality and youth in a context of intense dispute discourse produced by the school program “escola sem partido”. Aspects such as work and domestic environment, notions of instinct and male and female attitudes, motherhood and fatherhood constitute the narratives making it possible to invest in a post-structuralist inspired analysis of discourses and language as producers of subjects and knowledge, which permeates the deconstruction of binary gender perspectives. The experiences of young people are therefore constituted based on the ways in which gender conceptions are negotiated in the daily lives of young people.
PESQUISAS SOBRE GÊNEROS E SEXUALIDADES NA EDUCAÇÃO: TENTATIVAS DE VER, REVER E ‘TRANSVER’ O MUNDO
Authors: XAVIER FILHA Constantina
Published: July 2022

This article aims to describe research carried out within the Group of Studies and Research in Sexualities, Education, and Gender (Gepsex) at the Faculty of Education of the Federal University of Mato Grosso do Sul (UFMS). The researches are theoretically-methodologically based on gender studies, sexuality studies, feminist studies, cultural studies, and Foucault's assumptions, from a post-critical and poststructuralist perspective. We sought to think the research based on fragments of poetry by Manoel de Barros to discuss issues such as the deconstruction of unique truths; resistance in daily life and in doing research; the transience of scientific knowledge; questioning the meanings of language as the production of realities and subjectivities and thinking about the micro at the expense of metanarratives.Keywords: Research. Genre. Sexuality. Education.
PESQUISAS EM GÊNERO, SEXUALIDADE E EDUCAÇÃO NA PERSPECTIVA PÓS-ESTRUTURALISTA
Authors: Sarmento-Pantoja (UFPA) Augusto
Published: July 2022

The field of studies of gender and sexuality articulated with education has been constituting and, today is already consolidated as a field of knowledge. This means that this field has mobilized study and research groups linked to CNPq with a focus on these interests, lines of research in Postgraduate programs, National Associations focused on discussions of Gender and Sexuality, Working Groups in the main academic associations, Seminars National and International, in short, a set of actions that allow us to affirm the studies of Gender, Sexuality, and Education as a field that produces and disseminates knowledge. This field has a strong influence from the post-structuralist perspective, which invests in the problematization of important and central issues for society, such as, for example, the production of gender and sexual differences and inequalities in their crossings with race/ethnicity, generation, and class. Bringing it to Education, this approach focuses on the school space and a sense of education beyond schools as contexts in which gender and sexuality relations produce subjects as the effects of discursive practices, knowledge, power relations, and actions between subjects. In this sense, the proposal of a dossier like this is so that we can welcome, know and disseminate research that has taken the poststructuralist perspective in dialogue with other studies, such as Gay and Lesbian Studies, Foucaultian Studies, Cultural Studies, Feminist Studies, Queer Studies as provocations to think about the constitution of subjects and their belonging in their intersectionalities of gender, sexuality, race/ethnicity, generation, religion, class, among others. Research that works with this sense of constitution of subjects as educational processes that involve not only schools but other educational spaces as well, in which relationships are marked by discourses, practices, and knowledge that produce identities and belonging, as well as allowing us to place under suspicion our ways of thinking, acting, being and being in the world. Our proposal is also to problematize how these researches based on the post-structuralist perspective, in dialogue with other studies, have mobilized our ways of looking at and understanding the field of gender, sexuality, and education studies.KEYWORDS: Gender. Sexuality. Education. Post-Structuralism.
Desinformación y fact-checking en Ecuador. Análisis del rol informativo de la cuenta de Instagram de @ecuadorverifica
Authors: Hoyos-Simbaña Diego Paúl , Lara-Aguiar Jhonatan Andrés , Mila-Maldonado Juan Arturo
Published: July 2022

El presente artículo tiene como objetivo identificar cuáles son las principales características de la agenda mediática digital de la cuenta de Instagram de @ecuadorverifica, partiendo de criterios teóricos del fact-checking, con el objeto de caracterizar de qué manera se configura su agenda de cara a las elecciones presidenciales 2021 en Ecuador. Para ello, se lleva a cabo un estudio longitudinal de 6 meses, en el cual se han establecido como escenarios el antes, durante y después de las elecciones presidenciales del Ecuador. La metodología será de carácter cuantitativo, empleando el análisis de contenido para sistematizar cada una de las publicaciones emitidas por la página, y de esta forma someterlas a un manual de códigos previamente elaborado en miras de codificar cada uno de los mensajes, personajes y temáticas vinculadas al rol del Fact-checking y comprender su papel en materia de validación de la información dudosa que circula por las redes sociales.
Capabilities of long-term ECG monitoring in patients with myocardial infarction: the longer, the better?
Authors: Oleynikov V. E. , Averyanova E. V. , Oreshkina A. A. , Barmenkova Yu. A. , Kulyutsin A. V.
Published: July 2022

Background. In modern cardiology, 24-hour electrocardiogram (ECG) monitoring has a high diagnostic value, but this method has a number of disadvantages in detecting episodes of unstable life-threatening arrhythmias. An increase in ECG monitoring duration allows expanding the possibilities of diagnosing life-threatening arrhythmias.

Objective. To study the possibilities of long-term ECG monitoring (48–120 hours) in the detection of life-threatening arrhythmic events and parameters of myocardial electrical instability in patients with ST-segment elevation myocardial infarction (STEMI).

Design and methods. The study included 71 STEMI patients. All patients from the 4th day of STEMI underwent multi-day ECG monitoring in 3 leads using a telemetric ECG recording complex with an average recording duration of 90.4 ± 30.2 hours. The analysis of episodes of myocardial ischemia, rhythm and conduction disturbances, turbulence and heart rate variability, late ventricular potentials and dispersion of the QT interval within 5 days was carried out.

Results. Long-term monitoring allowed detecting high-grade ventricular extrasystoles. Analysis of episodes of myocardial ischemia in the postinfarction period revealed significant differences in the data of 120h-ECG monitoring in comparison with 24h-ECG. Multiday ECG monitoring made it possible to detect dysfunction of the autonomic regulation of cardiac activity in patients 2 times more often.

Conclusion. A comprehensive assessment of the possibilities of multi-day ECG monitoring is a promising direction in predicting severe arrhythmias in patients in the postinfarction period.
Spectrum of non-pathogenic variants in the titin gene and genes outside and intra-carcomeric cytoskeleton (TTN, MYBPC3, FLNC, RBM20) in patients with various variants of cardiomyopathy
Authors: Vakhrushev Yu. A. , Muravyov A. S. , Kozyreva A. A. , Zhuk S. V. , Rotar` O. P. , Kostareva A. A.
Published: July 2022

Background. Sarcomere protein genes such as MYBPC3, FLNC, TTN, RBM20 are associated with cardiomyopathies (CMP). A large number of rare genetic variants complicates the interpretation genetic studies and assessing the pathogenicity. Moreover, there is a lack of an information about rare variants frequency in a healthy Russian population. Polymorphisms in these genes often act as modifiers, aggravating the clinical course of CMP caused by mutations in other genes.

Objective. To compare the frequency of rare (less than 0.1 %) missense and truncating variants in the TTN, FLNC, MYBPC3, RBM20 genes in the patients with CMP and in the general population.

Design and methods. The CMP group included 251 patients. The control group included 192 men (from the ESSE-RF study). A molecular genetic examination was performed using high-processive sequencing technology, followed by verification by Sanger sequencing.

Results. The frequency of truncating variants in the genes TTN, FLNC, MYBPC3, RBM20 in the group with CMP was 7.17 %, and missense variants — 56.6 %: 11.5 % were pathogenic/likely pathogenic, 39.5 % — variants of uncertain significance, 49 % — probably benign/benign. The frequency of truncating variants in the TTN, FLNC, MYBPC3, RBM20 genes in the control group was 0.52 %, and the frequency of missense variants was 15.1 %: 38 % were variants of uncertain significance, 62 % — probably benign/benign.

Conclusion. Frequency of missense and truncating variants with a frequency of less than 0.1 % in the TTN, FLNC, MYBPC3, RBM20 genes was increased in the group of patients with CMP.
Certain aspects of radiomics and radiogenomics in glioblastoma: what the images hide?
Authors: Maslov N. E. , Trufanov G. E. , Efimtsev A. Yu.
Published: July 2022

Radiogenomics is a novel and promising field connecting a variety of imaging possibilities with various genomic events. Advances in genomics provided by the Cancer Genome Atlas and Human Genome projects made it possible to integrate this information with imaging phenotypes of malignant brain tumors for a more detailed understanding of their biology. Radiomics, in turn, lies at the intersection of radiology, computer science and mathematical statistics. Unlike radiogenomics, it does not focus on the specific relationship between the radiophenotype and tumor genotype, but rather identifies the analysis methodology. With its help, quantitative features are extracted from medical images, establishing patient’s genotype-phenotype correlation. This contributes to the risk stratification and patient management. The article discusses some topical aspects of radiomics and radiogenomics of glioblastomas and their application in neurooncology.

Previously, several groups of researchers showed the relationship between visualization features of glioblastomas and the prognosis of the course of the disease.

One of the modern problems of radiomics is the search for imaging features that can serve as key prognostic markers for risk stratification of patients with glioblastomas using machine learning tools.

Thus, the prospects for the development of radiomics and radiogenomics methods include predicting patient survival, differential diagnosis of glioblastomas, determining the degree of malignancy, identifying mutations and amplifications, detecting tumor progression, pseudoprogression, etc.
MODELAMIENTO DE UN SISTEMA FOTOVOLTAICO CONECTADO A LA RED CONSIDERANDO LA VARIACIÓN DE IRRADIANCIA SOLAR EN HOMER PRO
Authors: Figueroa Guerra Danner Anderson , Culqui Tipan Javier Fernando , Núñez Verdezoto Marlon Daniel , Cruz Panchi Omar Danilo
Published: July 2022

En la presente investigación surgió la necesidad de utilizar herramientas didácticas que permitieran conocer la mejor optimización de un sistema fotovoltaico para el abastecimiento de las cargas de una bananera. En correspondencia a lo anterior, este estudio presenta un modelo y simulación de un sistema conectado a la red, considerando la variación de la irradiancia solar. En primera instancia, se utilizó el instrumento piranómetro en la zona a estudiar. Luego se consideró las cargas de la bananera, para luego hacer uso de la herramienta HOMER Pro para hallar la mejor viabilidad del sistema fotovoltaico con sus algoritmos de optimización.  Para su validación se utilizó otros algoritmos de modelos matemáticos realizados en Matlab/Simulink, estableciendo la potencia del sistema, el costo nivelado de energía ($/kWh), como también el voltaje (V), corriente (A) y potencia (W) tanto del panel solar como la energía que sale a la carga, además, se determinó el punto de máxima transferencia de potencia (MPPT) del sistema. Por último, se evaluó el payback del modelamiento para conocer el tiempo de retorno de la inversión del sistema.
Screening Phytochemical and Study Insilico of Family Zingiberaceae as Anti-inflammatory
Authors: Kristianto Sonny , Isrianto Pramita Laksitarahmi , Marmi Marmi , Chamidah Dina , Khan Atta Ullah
Published: July 2022

Traditional medicine employs many ingredients that have been used for generations for treatment and are based on society's norms. These ingredients are referred to as jamu. The research aim was to determine the types and uses of medicinal plants, the active compound content, and the potential of traditional herbal medicine as a fever-lowering bio-computation. The traditional herbal formula was determined using a direct interview method combined with a purposive sampling technique in this study. We used the software for phytochemical screening and molecular docking. COX-2 was used to analyse proteins, and six ligands were used: Quercetin, Curcuminoid, Zingerone, Heyneanone, Zerumbone, and Sabinene. This study discovered 22 different types of medicinal plants in Bangselok village, East Java, Indonesia. The Zingiberaceae family is frequently used as an ingredient in herbal medicine. Ginger, Lempuyang, Bangle, Temu Mangga, Temu Putih, and Temu Giring contain flavonoid compounds. The docking results showed that Quercetin, Zingerone, Heyneanone, Zerumbone, and Sabinene ligands were attached to domain A by the control of natural COX-2 ligands, namely NAG and EDO, predicting that they could be used as an anti-inflammatory and the combination of active compounds recommended as herbal medicine.
Specific activity and features of vertical migration of strontium-90 in the peat bog of the Murmansk region
Authors: Lukoshkova A. , Yakovlev E. , Orlov A.
Published: July 2022

The peatlands of the Arctic territories are repositories of radioactive contaminations. The physicochemical properties, specific activity and features of vertical migration of 90Sr in the peat profile of the Murmansk region have been studied. A correlation matrix was compiled according to the studied indicators. The factor that determines the localization of 90Sr in peat has been established. The sources of isotope for the region were determined.

The reaction of the peat medium is acidic (4.2 ≤ pHwater ≤ 4.9; 3.6 ≤ pHsalt ≤ 4.1). The ash content of peat is medium and high (5.2 % ≤ Ash ≤ 28 %). The share of organic matter in the peat profile is more than 70 %. The upper part of the profile is saline (soluble salts>0.3%). The share of carbonates in the peat profile is insignificant (0.42–0.83 %).

90Sr activity (0.55–7.7 Bq/kg) was recorded in each peat sample. The activity of the technogenic radionuclide is below the established permissible norm and within the range typical for all Russian soils. The 90Sr isotope is localized in the upper layers of the profile and at a depth of more than 16 cm. The localization of 90Sr in peat layers is due to the content of water-soluble salts (r = 0.85). The main sources of the isotope for the Murmansk region are past global fallout from nuclear tests, the Chernobyl accident and current local fallout from nuclear fuel facilities.
Concepção de Justiça em Aristóteles
Authors: Denicol Karina A. , Bittencourt Paulo J. S.
Published: July 2022

A pesquisa centrou-se no conceito de justiça para Aristóteles, tendo por objetivo perquirir as bases históricas e filosóficas desse pensamento e contextualização com instituições existentes em Atenas e na Grécia na sua época, bem como o arcabouço político que permitiu o surgimento de suas teorias. Além disso, partindo da justiça como algo antropológico e não mais vinculado à religião, teve como intenção investigar as diversas noções de justiça para o filósofo, como justiça política, qual seja, aquela derivada da relação entre homens, estabelecida pelas leis. Ademais, centra-se na justiça distributiva, teleológica e justiça corretiva. Os resultados encontrados, por meio de pesquisa bibliográfica, de enquadramento histórico-contextual e de análise semânticoconceitual de textos filosóficos, demonstram que a evolução da noção aristotélica de justiça forjou tanto uma fundamentação revolucionária para a época em questão quanto uma tradição clássica de pensamento que esclarece as vinculações contemporâneas entre o Direito e a Ética.
Algunas Reflexiones Acerca de la “Mediación” en el Sector Financiero y Bancario. Especial Referencia a la Ley 7/2017 y el Anteproyecto de Ley de Medidas de Eficiencia Procesal del Servicio Público de Justicia de 2020
Authors: Cardona Noemí Jiménez
Published: July 2022

El presente artículo centra su principal hipótesis de estudio en la denominada “mediación en el sector financiero y bancario”, como manifestación sectorial y especializada de la mediación de consumo. Para alcanzar este fin el método utilizado se ha centrado en el análisis doctrinal y jurisprudencial sobre la materia, con especial referencia al tratamiento de los procedimientos extrajudiciales de resolución de conflictos en la Ley 7/2017 y el Anteproyecto de Ley de Medidas de Eficiencia Procesal del Servicio Público de Justicia (2020), así como a su particular aplicación en el ámbito de los créditos hipotecarios. Entre los resultados alcanzados, puede anticiparse que la utilización de la mediación en este ámbito puede ser útil para la protección de los consumidores si bien existen aspectos de la regulación actual como de la propuesta por el anteproyecto que deben ser objeto de una necesaria concreción jurisprudencial.
Los Derechos Fundamentales de la Víctima en el Proceso Penal
Authors: Rojas Gerardo Bernales , Mendes Lucivania Dias
Published: July 2022

La evolución del Derecho Penal y el Derecho Procesal Penal han ido en la línea de asegurar la aplicación de la pena justa al acusado y que ello sea el resultado de un proceso que cumpla con todas las garantías que aseguren un debido proceso. En esta órbita, los derechos del acusado se han desarrollado de manera exponencial, contemplando los sistemas normativos una amplia gama de derechos que el acusado, tanto en la investigación penal como en el juicio, en la sentencia y en la ejecución de la misma, puede ejercer. Es por ello que el presente trabajo quiere poner de relieve la marginación que se ha hecho, en esta evolución de los derechos, de quien estimamos es el principal sujeto en la comisión de un delito; la víctima. Tanto en Brasil como en Chile, marcos de referencia del presente trabajo, apenas hay reconocimiento meramente formal de derechos para las víctimas, careciendo de garantías y mecanismos que aseguren un efectivo acceso a la justicia. Como consecuencia de lo anterior, las víctimas no tienen asegurada una tutela judicial efectiva de sus escasos derechos, lo cual constituye una doble victimización de las mismas, lo que va no solo en contra de las tendencias del derecho comparado, sino que también contra la jurisprudencia de la Corte Interamericana de Derechos Humanos.
Analysis of Two Dimensional Sensitivity as Decision Support Alternative Waste Management in TPST Bantargebang
Authors: Sukwika Tatan , Sukamdani Nugroho Budisatrio , Maharani Maya Dewi Dyah
Published: July 2022

The importance of waste management at the TPST Bantargebang Bekasi is very high. Some sensitive issues such as pollution, social issues, and the requirement of wider area are several issues needed to be considered further. Therefore, this study tries to highlight the best alternative in waste management at the TPST Bantargebang with a two-dimensional approach using AHP (Analytical Hierarchy Process) analysis. Through a two-dimensional approach, it is hoped that adequate priority options can be found regarding alternative integrated waste management at the TPST Bantargebang Bekasi. Collecting data through expert interviews assisted by questionnaires, supported by other sources of data and information from various relevant agencies. The results of the two-dimensional sensitivity graph from the iteration of the three-goal criteria pair, namely waste management innovation, expansion of the TPST area, and strengthening regulations show that alternative decisions in integrated waste management at the TPST Bantargebang several times have raised alternatives to increase Human Resources (HR) to support activities. In conclusion, the most important alternative decision is to increase human resources. The policy implication of this study is that it is necessary to add more educated staff at the Bantargebang TPST so that the target of serving the needs of the community in terms of waste management can be carried out effectively, therefore, increasing human resources both in terms of competence and number is a priority to support the development of integrated waste management at the TPST Bantargebang.
University Students’ Attitudes towards using the Nearpod Application in Distance Learning
Authors: Musa Mofeed Ahmed Abu , Momani Jehad Ali Al
Published: July 2022

Creating a stimulating learning environment is a challenge in distance learning settings. This study aimed to investigate university students' attitudes towards using Nearpod in distance learning. For purposes of the study, the researchers developed a questionnaire of 20 items for which the validity and reliability were verified. The study sample consisted of 190 students. The students were taught different courses remotely in the second semester of the academic year 2020-2021 via Nearpod and Zoom. The results showed that the students had positive attitudes towards using Nearpod. In addition, the results showed that teacher support was the most important variable (x ̅=3.69), while student interaction and participation via Nearpod was predicated by students. Using appropriate applications to increase teacher support and student interaction is the most important variable in distance learning settings. The results also showed that there were no statistically significant differences (α = 0.05) attributed to the gender and academic stage variables.
Development and Testing of Modified Alumina Catalysts for Hydrotreating Petroleum Gasoline Fraction
Authors: Tuktin Balga , Omarova Aizhan A. , Sassykova Larissa R. , Saidilda Galymzhan T. , Subramanian Sendilvelan , Tulepov Marat I. , Abilmagzhanov Arlan Z.
Published: July 2022

The oil produced in the oil fields of the Republic of Kazakhstan contains a high percentage of sulfur. Synthesis and improvement of the properties of catalytic systems for the production of fuels with high octane number and low sulfur content is currently an urgent task for Kazakhstan. In this study, catalytic systems with a new composition based on zeolites with the addition of rare-earth metals (E) and phosphorus (P) have been prepared and tested in the process of the catalytic hydrotreating of straight-run gasoline and gasoline of catalytic cracking. In case of NiO-MoO3-E-P-HZSM-HY-Al2O3 catalyst, the octane rating of the gasoline after hydro-processing was increased to 88-90, which is much higher than for other catalysts. The octane number of straight-run gasoline up to 400°C is a maximum of 90 (Research Method) and 83.7 (Motor Method). At the same time, the sulfur content in the resulting gasoline decreases from 0.0088% to 0.0011%. In the case of catalytic cracking gasoline, the sulfur content is reduced from 0.0134% to 0.0012%. The smallest residual sulfur content in the final product, 0.0005% is revealed in case of catalyst CoO-WO3-E-P-HZSM-HY-Al2O3, and it is 2-4 times lower than for catalysts CoO-MoO3-E-P-HZSM-HY-Al2O3 and NiO-MoO3-E-P-HZSM-HY-Al2O3. These amounts of sulfur residue in raw materials is lower than that required by the Euro-5 Standard. The surface of the prepared catalysts was 211.0-274.0 m2/g, diameter of pores d ≈ 1.5-2.5 nm and d ≈ 7.0 nm. The total pore volume of the catalysts was not higher than 0.28-0.41 ml/g. The catalysts developed in this study can be used for hydrotreating raw materials and producing high-octane gasoline with a low sulfur content, corresponding in its characteristics to the Euro-5 Standard.
Telling the Wave Function: An Electrical Analogy
Authors: Chiatti Leonardo
Published: July 2022

The double nature, wave and corpuscular, of the material particles is usually considered incomprehensible as it cannot be represented visually. It is proposed to the student, in the introductory courses, as a fact justified by quantum interference experiments of which, however, no further analysis is possible. In this note we propose a description of the wave function in terms of a simple electrical analogy, which reproduces at least some of its essential properties. The aim we propose is to provide a cognitive representation of an analogical type: starting from a classical context (electrical circuits) and introducing in an appropriate way the notions of "wave" and "particle", we show how typically quantum properties such as delocalization and entanglement emerge in a natural, understandable and intuitive way.
Diskursus Akad Pembiayaan Bank Syariah dalam Perspektif Hukum di Indonesia
Authors: Hana Kharis Fadlullah , Dimam Islahud
Published: July 2022

This research focuses on the process of forming Islamic bank financing contracts in general. Which distinguishes between two sorts of deeds: genuine deed and private deed. In addition, the search for information on how the OJK product standards are used in financing contracts, as well as the requirements of the Indonesian law that governs the drafting of the deed, which contains sections of the whole deed. In addition, the researchers made modifications based on the data acquired and provided and detailed how to make and prepare a good and accurate act that was suitable based on Indonesian legal requirements. A explanation of how the form of correctness and duty of a notary in making the contract was also included by the researcher. The inclusion of components that constitute the foundation of sharia principles taken from the Qur'an and Hadith at the commencement of the deed would weaken the legitimacy of the deed and will receive sanctions, specifically the deed will be degraded into a deed under hand, according to this research. Then there are the findings of many infractions that may face similar consequences in the future.
Human Error Analysis to Minimize Work Accidents Using the HEART and SHERPA Methods at PT. Wonojati Wijoyo
Authors: Noventya Cahyani Salma , Safirin M. Tutuk , Donoriyanto Dwi Sukma , Rahmawati Nur
Published: July 2022

PT Wonojati Wijoyo is a company that produces furniture for export. In carrying out the production process, work accidents often occur. One of the causes is the factor of human negligence. Work accidents that have occurred include torn wounds due to being hit by a machine, legs hit by wood to make them swollen, fingers hit by machines to open wounds, fingers caught in blocks to open wounds. This study aims to determine the value of Human Error Probability (HEP) and recommend improvement strategies for activities that have the potential to cause human errors to minimize work accidents. The method used in the analysis of human error is the HEART method and the SHERPA method. The results showed that there are critical activities that have the potential for human error to occur, namely in 14 subtasks of 9 processes. The highest probability of human error is in the subtask of cutting wood plates using a circle machine with a HEP value of 0.88827 including the high category. While the lowest probability of human error is in the subtask of setting a copy machine with reference wood with a HEP value of 0.00372 including the medium category. One of the recommendations for improvement strategies to minimize work accidents is that the company needs to conduct training on K3 on a scheduled basis with an explanation of the risks that occur if you do not use Personal Protective Equipment (PPE).
Government Policy Analysis to Develop the Krian-Manyar-Gresik Toll in order to Reduce Traffic Jam using A Dynamic System Approach
Authors: Sukma Dwi , Nugraha Isna , Rahmawati Nur , Syamsiah Yuliatin Ali , Alfani Ahmad Mujaddid
Published: July 2022

Infrastructure development in an area, including the construction of toll roads, is aimed at developing a region and increasing the economy of the region. The construction of the toll road which is connected from Krian-Manyar-Gresik is carried out to facilitate traffic connecting the two cities. Traffic jams often occur at the link between the two cities. Congestion that occurs is usually caused by an increase in the volume of vehicles. Therefore, the construction of a toll road connecting the two cities is the best alternative. This research aimed to know  government policies effectiveness in the construction of this toll road. The method used in this research is to use a dynamic system approach. From the results of the traffic simulation model design, it is found that the construction of toll roads is considered very influential and can be a way out of congestion problems. This is due to a decrease in the degree of saturation of congestion and although there is an increase from year to year, it is only slightly and not too significant. So the researchers suggest to continue the planned toll road construction project.
How the Covid-19 pandemic has drawn attention to the issue of active mobility and co-benefits in Latin American cities
Authors: Peden Margaret , Puvanachandra Prasanthi , Keller María-Eugenia , Rodrigues Eugenia-Maria , Quistberg Alexander , Jagnoor Jagnoor
Published: July 2022

The Covid-19 pandemic has brought to the fore many issues that will impact public health for years to come –one such impact is on the nexus between transportation and health. Promoting safe, active transport is an activity that has many physical and mental health benefits. During lockdowns, many cities in Latin America imposed infrastructural and legislative changes in order to abide with public health and social mea­sures to reduce virus spread. These ranged from additional bike lanes to reduced speed limits or incentives to purchase bicycles. These cities showed reduced motorized transport, improved air quality and increased active transport, all of which have multiple health and equity benefits. As countries “build back better”, promoting active transport offers the most value for investment and improves health and well-being while continuing to offer social distancing. Quantified case studies are needed to have a more comprehensive under­standing of the impact of active transport in various contexts.
Going digital: opportunities and barriers in the use of technology for health research
Authors: Blumenberg Cauane , Peiris David , Loret de Mola Christian , Sinnadurai Manohan , Tian Maoyi , M Beleigoli Alline , Lazo-Porras Maria , Diez-Canseco Francisco , Paredes Miguel , Labán-Seminario L Max , Zafra-Tanaka Jessica Hanae , Praveen Devarsetty , Miranda J Jaime
Published: July 2022

Digital health refers to the use of novel information com­munication technologies in healthcare. The use of these technologies could positively impact public health and health outcomes of populations by generating timely data, and facili­tating the process of data collection, analysis, and knowledge translation. Using selected case studies, we aim to describe the opportunities and barriers in the use of technology applied to health-related research. We focus on three areas: strategies to generate new data using novel data collection methods, strategies to use and analyze existing data, and using digital health for health-related interventions. Exemplars from seven countries are provided to illustrate activity across these areas. Although the use of health-related technologies is increasing, challenges remain to support their adoption and scale-up –especially for under-served populations. Research using digital health approaches should take a user-centered design, actively working with the population of interest to maximize their uptake and effectiveness.
Efficient Water Softening in Heavy Oil Steamflood Operations
Authors: Prakash Prakhar , Concienne Reid , Demayo Trevor , Towne Kirsten
Published: July 2022

Pigging of once through steam generators (OTSGs) has indicated various types of scales, the most predominant of these being silicates of hardness causing ions. It was noted that scaling propensity can potentially go up with higher steam quality (SQ) as the reject stream gets concentrated with ions. However, models suggested that there are benefits of higher SQ in enhancing fuel savings (8%) and electricity savings (2%) when SQ was increased by 20%. The challenges of higher SQ were noted in terms of increased scaling tendency and therefore the need for improved softening. In Field D, the service cycle, the backwash cycle, and the brining cycle were optimized leading to a gain in throughput and reduction in salt consumption. Service cycle improvement gained 30 to 130% in throughput between two regenerations, backwash cycle improvement by fluidizing the bed to nearly 35% helped gain 10% in throughput, and reduction of brining cycle from 75 to 48 minutes helped reduce salt consumption by 56% without impacting the throughput. In Field B, a 6-month pilot revealed that shallow shell resins where ion exchange is more efficient due to inert core (better intraparticle diffusion control) can enhance the throughput by 30 to 80% and simultaneously reduce the number of regenerations by 15 to 30%. Resin fouling is still a major challenge to contend with as oil can foul the resin and throughput can decline by 0.5 to 3 folds. In a plant operation, where there are multiple softener and brine vessels, there is a need to optimize them as a system. Reliability, availability, and maintainability (RAM) models are used in Field C to (a) address equipment configuration optimization with impact on capital capacity expansion project scope, (b) understand how net soft water delivery capacity was affected by increases in inlet hardness, and (c) assess through a comparison scenario if the large cost of addressing the valve issue in an upstream nutshell filter was worth the lost production opportunity related to unplanned downtime.
A Blockchain-assisted Lightweight Anonymous Authentication Scheme for Medical Services in Internet of Medical Things
Authors: Wu Shu , Zhang Aiqing , Chen Jindou , Peng Guangyu , Gao Ya
Published: July 2022

Internet of Medical Things (IoMT) enable physicians to provide precise care over the Internet for registered patients anywhere, bringing convenience to people’s everyday life. Considering the importance of patient’s privacy in IoMT, data security between patients and medical servers should be protected. Therefore, the authentication of identity and the agreement of a shared secret key are particularly important. In this work, we propose a lightweight anonymous authentication scheme between patients and medical servers in IoMT. We combine blockchain technology with biometric technology in order to form a shared session secret key. It can protect the privacy of patients through mutual authentication between patients and servers. Afterwards, the formal analysis of BAN logic shows that our scheme is secure. Non-formal analysis shows that our scheme achieves designed security objectives. Finally, we implement the cryptography primitives to verify our scheme. Comprehensive comparative experiments show that our proposed scheme achieves a better performance in both computation and communication efficiency.
Optimal Performance Evaluation of Localization of Sensor Nodes in Wireless Sensor Networks
Authors: Gupta Akanksha , Singh Umang
Published: July 2022

Wireless Sensor Networks are a collection of numerous nodes which contain tiny devices having low power and work with minimal cost. In such a network, the functioning of these nodes plays a very important role to sense data and also forward the sensed data to the target observer. For segregation of nodes in effective locations, there is a need to localize these nodes by combining location information with the sensed data for tracking and monitoring of malicious nodes, goods tracking etc. The approaches towards localization may be classified as range-free or rangebased, both having their own pros and cons. This paper presents a discussion on different localization approaches, followed by simulation results of localization using lognormal shadowing model for distance estimation and trilateration for location computation. The results depict the individual impacts of node density and area of sensed region on the localization error. The approach used is cost effective, since it uses loss in received power for distance computation and hence there is no cost overhead for additional hardware.
TTC22 promotes m6A-mediated WTAP expression and colon cancer metastasis in an RPL4 binding-dependent pattern
Authors: Deng Dajun , You Abin , Tian Wei , Yuan Hongfan , Gu Liankun , Zhou Jing
Published: July 2022

WTAP, an essential component of the RNA N-6-methyladenosine (m6A) modification complex, guides METLL3-METLL14 heteroduplexes to target RNAs in the nuclear speckles of mammalian cells. Here, we show that TTC22 is widely coexpressed with WTAP and FTO in many human tissues by mining Genotype-Tissue Expression (GTEx) datasets. Our results indicate that the direct interaction of TTC22 with 60S ribosomal protein L4 (RPL4) promotes the binding of WTAP mRNA to RPL4, enhances the stability and translation efficiency of WTAP mRNA, and consequently increases the level of WTAP protein. Also, WTAP mRNA itself is an m6A target and YTHDF1 is characterized as an essential m6A binding protein in WTAP mRNA. TTC22 triggers a positive feedback loop between WTAP expression and WTAP mRNA m6A modification, leading to an increased m6A level in total RNA. The knockdown of RPL4, WTAP, or YTHDF1 expression diminishes the TTC22-induced increase in the m6A level of total RNA. Thus, TTC22 caused dramatic expression changes in genes related to metabolic pathways, ribosomal biogenesis, the RNA spliceosome, and microorganism infections. Importantly, TTC22 upregulates the expression of SNAI1 by increasing m6A level and thus promotes lung metastases of colon cancer cells in mice. In conclusion, our study showed that TTC22 upregulates WTAP and SNAI1 expression, which contributes to TTC22-induced colon cancer metastasis.
If postoperative radiotherapy seemed to have survival benefit in rectal cancer with pT1-3N1M0 of patients undergoing primary surgery in the TME era
Authors: Chen Jinhu , Ye Qing , Huang Feng
Published: July 2022

Purpose At present, for some patients with stage III rectal cancer without neoadjuvant therapy before operation, NCCN guidelines still recommend routine postoperative adjuvant radiotherapy and chemotherapy. This study aimed to evaluate the value of postoperative radiotherapy in patients with low-risk disease (pT1-3N1M0) who did not receive preoperative neoadjuvant therapy in the TME era.Methods Patients with pT1-3N1M0 rectal cancer, who undergone radical surgery for initial treatment and adjuvant chemotherapy , were recruited retrospectively from the SEER database(2004‐2016) . A propensity score model was utilized to balance baseline covariates. Results Of the 2012 included patients, 1384 patients received adjuvant chemo-radiotherapy (radio group) and the remaining 718 patients did not, only for chemotherapy alone (no-radio group). There was no significant difference in cancer-specific survival between patients who received adjuvant radiotherapy or not (Log Rank test X ²= 2.372, P=0.124) in the overall sample. In the propensity score-matched cohort, adjuvant radiotherapy also did not improve cancer-specific survival. The subgroup analysis showed that the number of positive lymph nodes equal to 3 and the tumor size larger than 50mm subgroup combined with postoperative adjuvant chemotherapy could improve tumor specific survival rate, while other cases could not benefit from postoperative radiotherapy.Conclusion For all pT1-3N1M0 patients, who without neoadjuvant therapy before operation, radiotherapy in addition to postoperative adjuvant chemotherapy does not significantly improve survival. The number of nodes positive as 3 and tumor size > 50mm may be the screening indicators for postoperative adjuvant radiotherapy.
The effects of genistein supplemented before or after irradiation on DNA injury in human lymphocytes in vitro
Authors: Dobrzyńska Małgorzata M. , Gajowik Aneta
Published: July 2022

Purpose. The study aimed at the investigation if application of genistein (GEN) at different time prior or past irradiation may avert or reduce the induced by irradiation injury of DNA in human lymphocytes. Materials and Methods. The isolated lymphocytes were exposed to X-irradiation (0.5; 1 Gy). GEN (1 µM/ml; 10 µM/ml) was appended to attempts at various times prior or past irradiation (1 h prior, immediately prior, immediately past, 1 h past). We joined each X-rays dose with each GEN dose. After 1h of incubation DNA damages were examined using Comet assay. Results. Combination of 1 µM/ml of GEN given 1 h before irradiation with low or high dose markedly decreased induced by irradiation DNA injury. Higher dose of GEN applied immediately before or after irradiation markedly extended the frequency of DNA injury generated by irradiation. The result of application 1 µM/ml GEN 1 h after irradiation was not significantly different compared to control. The effect of 1 Gy + 10 µM/ml GEN was not significantly lower compared to each agent alone.Conclusions. Only a very low concentration of GEN was applied before irradiation, it may be considered as a potential radiomitigator/radioprotector. High doses of GEN work as a radiosentitizer and may potent the effects of radiotherapy.
The Spectrum of Imaging Manifestations of Gorham–Stout Disease
Authors: Lee Yuna , Lee Seunghyun , Hur Saebeom , Jeong Yun Soo , Suh Dong In , Moon Jangsup , Kim Man Jin , Choi Young Hun , Cheon Jung-Eun
Published: July 2022

Background
To describe the radiological features of Gorham–Stout disease (GSD) as evaluated using plain radiography and dynamic contrast-enhanced magnetic resonance lymphangiography (DCMRL) imaging techniques.
Methods
Clinical and conventional imaging data were retrospectively reviewed for 15 patients with GSD between January 2001 and December 2020. After December 2018, DCMRL examinations were performed for lymphatic vessel evaluation in patients with GSD and reviewed in four patients.
Results
The median age at diagnosis was 9 years (range: 2 months–53 years). The clinical manifestations were dyspnea in seven patients (46.7%), sepsis in 12 (80.0%), orthopedic problems in seven (46.7%), and bloody chylothorax in seven (46.7%). The common sites of osseous involvement were the spine (73.3%) and pelvic bone (60.0%). Among the non-osseous involvements, peri-osseous infiltrative soft-tissue abnormalities adjacent to the area of bone involvement were the most common (86.7%), followed by splenic cysts (26.7%) and interstitial thickening (26.7%). DCMRL demonstrated weak central conducting lymphatic flow in two patients with abnormal giant tortuous thoracic ducts and no flow in one patient. All patients who underwent DCMRL in this study presented with altered anatomical lymphatics and functional flow with collateralization.
Conclusion
DCMRL imaging and plain radiography are very useful for determining the extent of GSD and are essential for diagnosis. DCMRL is an essential imaging tool for the visualization of abnormal lymphatics in patients with GSD, which helps in further treatment. Therefore, in patients with GSD, it is necessary to obtain not only plain radiographs but also MR and DCMRL images.
Terahertz Wave Excitation by Nonlinear Coupling of Intense Laser Field with Magnetized Plasma
Authors: Hassan Munther B. , Abd-Ali Ibtisam Jaafer , Mahdi Wissam H. , Alkhayatt Adel H.Omran
Published: July 2022

In this article, the plasma wave density is playing vast role firstly to generate a coherent THz wave then enhancing its stability and increasing its intensity. Due to the relativistic increase of electron mass, the relativistic self-focusing of a right circular polarized laser beam (RCP) inside magnetized plasma will occur which leads to raising the laser power to enough limits for exciting the terahertz wave. By fulfilling the energy-momentum conservation conditions, a terahertz wave frequency at the difference between the laser pump wave frequency and plasma wave frequency is obtained. More stabilization and higher power (reaching tens of gigawatts) of terahertz field amplitude have been observed whenever the plasma frequency is increased. Better results are recorded at high THz frequency (5 THz) compared with low THz frequency (0.5 THz).
Digital Learning Designs in Occupational Therapy Education: A Scoping Review
Authors: Hwang Na-Kyoung , Shim Sun-Hwa , Cheon Hye-Won
Published: July 2022

Background: Digital learning is a rapidly advancing method for teaching and learning in professional health education. Although various digital learning designs have been tried in OT education, studies on digital learning designs are still limited. Methods: We conducted a scoping study to aims to identify the digital learning designs used in occupational therapy (OT) education and review the effectiveness, learner perceptions, clinical skills integrated, and technology-based learning strategies used to facilitate learning. Four databases were searched using subheadings and terms relating to digital learning, occupational therapy and education. The included studies were mapped according to the types of digital learning design, subject, key clinical skills, and outcomes. Results: Twenty-two studies were included in this review, most of which were qualitative, observational, or mixed studies of the two designs. The digital learning designs identified in OT education were flipped, blended, hybrid, and distance learning, including e-learning and massive open online courses (MOOC). Among the components of clinical skills, clinical reasoning and procedural knowledge were the most integrated into digital learning, and covered various OT subjects. Digital learning designs were reported to be equivalent to or more effective than the traditional face-to-face (F2F) class in learning outcomes of knowledge and skill acquisition, enhancing learning participation, reflection, and collaboration between learners. Various technologies have been used to promote synchronous or asynchronous active learning, providing learning strategies such as thinking, reflection, discussion, peer learning-group activity, and gamifying online learning. Conclusions: In OT digital learning, appropriate learning subjects, the arrangement of clinical skill components that can be well integrated into digital learning, and the selection of appropriate technologies for effective learning are important. The results should be confirmed within an experimental study design.