bluuebunny/crossref_metadata_2025 huggingface dataset:
TRANSARTERIAL CHEMOEMBOLIZATION(TACE) EFFICACY IN PATIENTS WITH HEPATOCELLULAR CARCINOMA(HCC): CAN SIGNIFICANT PROGNOSTIC FACTORS BE REVEALED?
Authors: Breder Valeriy , Dolgushin Boris , Kukushkin Anatoliy , Trofimov Igor , Kosyrev Vladislav , Kostyakova Lyudmila , Virshke Eduard , Laktionov Konstantin , Dzhanyan Irina , Pitkevich M.
Published: November 2020

Material and methods. A total of 125 patients(pts) with HCC (stage BCLC-B) underwent TACE from 2009 to 2016. If pts had been found inoperable, radiological intervention was used as monotherapy or in combination with systemic therapy at different stages of the disease.
Results. Median overall survival (OS) for pts subjected to at least one TACE session was 20.5 months (95 per cent confidence interval 16.4-24.59). Such factors as ECOG status (р=0,012, RR= 1,65), protein synthesis (albumin >37 г/л; р=0,005, RR = 0,47) and detoxication (total bilirubin ≤ 14 мкмоль/л; р=0,037, RR = 1,64) hepatic functions, functional hepatic ability according to Child-Pugh classification (А vs. B; p=0,016, RR = 2,5) ALBI categories (A1 vs. A2 vs. A3; р=0,007, RR = 1,66) as well as HCC invasion: tumour size (р=0,001, RR=2,1), level AFP ≥ 5 IU/ml (р=0,003, RR 2,25), bilobar involvement (р=0,024; RR=1,64) independently influence OS. Pronounced TACE effect (р<0,001, RR 1,93) and Time before Progression duration were found to influence significantly the fatality rate. Multifactorial analysis for OS confirmed increased mortality (RR=1,92) if total bilirubin was ≥14 umol/L (р=0,018); Impaired hepatic functions according to ALBI (р=0,007) and Child-Pugh classification (р=0,002) are associated with significant OS reduction (RR 1.73 и 3,41respectively). HCC invasion (BCLC; р=0,03) AFP level ≥5 IU/ml (р=0,008, RR=2,26) and the biggest tumour node size >10 см (р=0,01, RR 1,95) independently increase mortality rate. Effective TACE (р<0,001) is associated with significant OS increase and mortality decrease.
Conclusion. TACE is most effective if HCC pts have satisfactory condition and preserved liver function (Child Pugh A or ALBIA1) and limited intrahepatic invasion (BCLCA/B), with tumour size being... cm and normal AFP level. Under conditions of intrahepatic progression subsequent local therapy was found to be significantly associated with OS increase.
PET/CT WITH 68GA-PSMA-11 IN DETECTION OF PRIMARY TUMOR AND RECURRENCE OF PROSTATE CANCER
Authors: Ryzhkova Darya , Poyda M.
Published: November 2020

Purpose: To study the diagnostic value of PET-CT with 68Ga-PSMA-11 in the diagnosis of a primary prostate cancer, preoperative staging, and the detection of recurrence of prostate cancer (PCa).
Methods: 28 patients aged 64.7 ± 8.74 years were included. 10 patients primary prostate cancer, and 18 patients with biochemical recurrence of the disease after radical treatment were examined. All patients underwent PET-CT with 68Ga-PSMA-11 according the whole body protocol. Interpretation of images was performed visually and quantitatively by calculation of SUL max.
Results: High focal or diffuse 68Ga-PSMA-11 uptake was found in prostate parenchyma in patients with primary prostate cancer. Additionally metastases in regional lymph nodes were diagnosed in 4 patients and bone metastases were found in one patient. The correlation between 68Ga-PSMA-11 uptake level and Gleason index in the primary tumor (R Spearmen = 0.25, p = 0.57) was not observed. PET-positive results were obtained in 14 patients and PET-negative results in 4 patients with biochemical recurrence of PCa. The relationship between the frequency of PET-positive results and Gleason index was not revealed (R Spearmen = 0.2, p = 0.39). We found a weak but significant correlation between the frequency of PET-positive results and the prostate tumor stage according to the T category (R Spearmen = 0.49, p = 0.049). In patients with low values of PSA (less than 1.0 ng/ml) in 4 out of 9 cases, PET-negative results were obtained. In patients with PSA level more than 1.0 ng/ml PET-positive results were obtained in all cases.
Conclusions: PET/CT with 68Ga-PSMA-11 allows to diagnose the primary prostate cancer, to establish the stage of the disease in categories N and M, and also to determine the localization and dissemination of the tumor in patients with biochemical recurrence of prostate cancer. The relationship between 68Ga-PSMA-11 uptake in primary tumor and Gleason index was not found. The probability of obtaining PET-positive results in cases of biochemical recurrence is affected by a PSA level above 1 ng/ml and a high stage of the disease according to the T category (T3-T4).
DYNAMICS OF CONCENTRATIONS OF NO-SYSTEM COMPONENTS DURING B16/F10 MELANOMA GROWTH IN FEMALE MICE WITH CHRONIC NEUROGENIC PAIN
Authors: Kit Oleg , Frantsiyants Yelena , Kotieva Inga , Surikova Yekaterina , Kaplieva Irina , Bandovkina Valeriya , Trepitaki Lidiya , Pogorelova Yuliya , Sidorenko Yuriy
Published: November 2020

Since chronic neurogenic pain has been reported to affect biological characteristics of B16/F10 melanoma, the purpose of the study was to analyze concentrations of components of the NO-system in mice during the growth of transplantable B16/F10 melanoma combined with chronic neurogenic pain.
Methods. The study included 64 female mice. Melanoma was transplanted under the skin of the back to animals of the main group 2 weeks after the bilateral sciatic nerve ligation. Levels of NOS-3, NOS-2, endothelin-1, L-arginine, citrulline, total nitrite and ADMA were determined by ELISA in the intact skin and in tumor tissues.
Results. The study showed that the dynamics of the studied parameters differed in tumor growth alone and in combination with chronic pain. Stably increased levels of NO-synthases in the tumor and stably increased ADMA levels with their decrease by week 3 of the growth were registered in the tumor growth with pain.
Conclusions. Chronic pain probably contributes to the development of immunological tolerance to tumor antigens in the skin. Conditions are formed that facilitate the survival of tumor cells and contribute to the further development of melanoma. The dynamics of the NO-system activity can stimulate neoangiogenesis and enhance tumor invasion. Changes in the ADMA inhibitor levels in the tumor growth combined with chronic pain may indicate the control of NO levels through the metabolic regulation of NO-synthase activity, thus providing increased melanoma invasiveness.
COMBINED DIAGNOSTICS OF LUNG CANCER USING EXHALED BREATH ANALSYSIS AND SPUTUM CYTOLOGY
Authors: Arseniev A. , Nefedova A. , Ganeeva A. , Nefedov A. , Novikov S. , Barchuk Anton , Kanaev S. , Jahatspanian I. , Gubal A. , Kononov A. , Tarkov S. , Aristidov N.
Published: November 2020

In this article we summarize our own experience of lung cancer diagnostics using exhaled breath analysis with a non-selective method using metal oxide chemoresistor gas sensors with cross-sensitivity combined with the sputum cytology. Volatile organic compounds of exhaled breath change the conductivity of the sensor, the resulting pulse is displayed as a peak on the graph, the area of which is used as test results. The combination of two diagnostic techniques in 204 participants demonstrated the possibility of non-invasively detecting the disease at an early stage. The sensitivity, specificity and accuracy of the breath analysis was 91.2%, 100% and 93.4%, respectively. The combination of the breath test and the sputum cytology compared to the breath test alone showed statistically significant (p = 0.03) increase in sensitivity to 96.8% (95% CI: 80.9% -99%) with acceptable decrease in specificity to 93.4% (95% CI: 88% -96%). The convenience of analysis and realtime measurements show some promise for the early detection.
Practical Experience of Using Riamilovir in Treatment of Patients with Moderate COVID-19
Authors: Sabitov A. U. , Belousov V. V. , Edin A. S. , Oleinichenko E. V. , Gladunova E. P. , Tikhonova E. P. , Kuzmina T. Yu. , Kalinina Yu. S. , Sorokin P. V.
Published: November 2020

The article evaluates the results of Riamilovir use in treatment of patients with a moderate form of the disease caused by a new strain of the SARS-CoV-2 virus. It was found that the average time required to complete resolution of symptoms during treatment with the drug was 6-7 days. The first negative result of PCR analysis for the SARS-CoV-2 virus was registered on the 10-11th day of therapy; two consecutive negative PCR results for the SARS-CoV-2 virus were registered in the majority of patients by day 14–19 of treatment in 63±4.28%. The body temperature of the majority of patients (75%) returned to normal by the 4th day of treatment. CT scan showed improvement in the lungs of patients: a repeated CT scan performed on average on day 19 from the start of therapy showed no lung damage or no progression in 10±3.0% of patients following therapy. The CT scan of the lungs performed in 1-2 months after the treatment showed that the number of patients with no lung damage increased to 27±4.44%. As a result of treatment, a decrease in the C-reactive protein index was observed in patients. The tolerability level of the drug was assessed as good: no adverse events or significant deviations in laboratory parameters were detected.
The Development of a Turbidimetric Method for the Quantitative Determination of Antibiotics of the Aminoglycoside Group in Medications
Authors: Semenova E. N. , Kuleshova S. I. , Sakanyan E. I.
Published: November 2020

A method for the quantitative determination of streptomycin sulfate in medicines by the turbidimetric method has been developedand validated. Based on the results of the experiments, it was found that the metrological characteristics of such validation parameters of the method as linearity, precision, and correctness do not exceed the validation criteria. Linearity was noted in the range of streptomycin concentrations from 3.75 to 8.43 μg/ml. The results of validation tests of the method for the quantitative determination of streptomycin indicate the prospects and feasibility of introducing the turbidimetric method into the domestic system for standardization and quality assessment of aminoglycoside antibiotics.
«La intensificació retòrica del elements morbosos en les faules mitològiques de Joan Roís de Corella: de la imitatio a la innovació estètica»
Authors: Alemany Ferrer Rafael
Published: November 2020

Resumen: Les faules mitològiques, amb les quals Roís de Corella inicia la seua carrera literària, són exercicis escolars destinats a l’ensinistrament en l’escriptura en prosa. Cadascun d’aquests textos reescriu, amb trets originals, un tema ja tractat anteriorment per autors prestigiosos. Una de les innovacions que hi aporta Roís de Corella és l’amplificació retòrica de les seqüències més morboses d’aquestes faules, dins d’una proposta estètica caracteritzada per l’exacerbació sentimental i l’efectisme. Així es dedueix de l’acarament d’algunes de les seqüències més tràgiques d’una selecció d’aquests relats (el Plant dolorós de la reina Hècuba, la lletra de Medea, la lamentació de Mirra i les històries de Pasífae i de Tereu, Procne i Filomela) amb els models literaris corresponents.Paraules clau: Roís de Corella, faules mitològiques, elements morbosos, intensificació retòrica, models literaris.«Rhetoric intensification of morbid elements in the mythological tales by Joan Roís de Corella: from the imitatio to the aesthetic innovation»Abstract: The mythological tales, with whom Roís de Corella began his literary career, are school exercises for training in prose writing. Each of these texts is dedicated to rewrites, with original features, a subject previously dealt by prestigious authors. One of the innovations that Roís de Corella offers is a rhetorical amplification of the more ghoulish sequences of these fables, in an aesthetic proposal characterized by sentimental exacerbation and sensationalism. This is deduced from the comparison between some of the most tragic sequences of a selection of these short stories (the Plant dolorós de la reina Hècuba, Medea letter, lamentation of Mirra and the stories of Pasífae and Tereu and of Procne and Filomela) with their corresponding literary models.Keywords: Roís de Corella, mythological tales, ghoulish elements, intensifying rhetoric, literary models.
«Cabayong tabla: estudi i traducció d'un romanç filipí del regne de València (II)»
Authors: Donoso Isaac
Published: November 2020

Resumen: Introducció a la conformació del romacer de tradició hispànica a les illes Filipines i la presència del Regne de València com espai literari en una literatura asiàtica. Al treball acompanya la descripció i traducció directa des del bicolà al valencià d’un dels principals romanços filipins que tracten del Regne de Valencia: Cabayong Tabla. Buhay ni Principe don Juan Asin ni Princesa Dña. Maria Sa Cahadean nin Valencia asin Asturias –«Cavall de Taula»–, text per primera vegada traduït a qualsevol llengua. Així mateix, analitzem les fonts i descrivim la història argumental i la presència de València al Romancer filipí con a treball comparatista que puga donar llum a la formalització del classicisme en les Lletres Filipines des de la literatura medieval de tradició hispànica.Palabras clave: Romancer hispànic, awit i corrido, Filipines, Regne de València, literatura hispànica, bicolà.Abstract: The paper introduces the development of the Philippine metrical romances from the Hispanic tradition and the presence of the Kingdom of Valencia as Asian literary topic. It is supplied with the first translation ever done from the original Bicolano into Catalan of one of the most relevant romances dealing with the Valencian topic: Cabayong Tabla. Buhay ni Principe don Juan Asin ni Princesa Dña. Maria Sa Cahadean nin Valencia asin Asturias –«Wooden Horse». We analyse the sources and the plot of the romance in order to compare and enlight the genesis of Philippine Classical Literature with the Medieval Hispanic Romancero.Keywords: Hispanic Romancero, Philippine Metrical Romances, awit and corridor, Philippines, Kingdom of Valencia, Bicolano.
El microtexto de la "Poética del desamor" en las Rimas de Boccaccio
Authors: Blanco Valdés Carmen Fátima
Published: November 2020

Resumen: Sobre la base de la posibilidad de acercarnos al estudio de las Rimas de Giovanni Boccaccio a través del establecimiento de determinados núcleos temáticos que permiten un estudio de esta obra desde los enfoques macrotextuales y microtextuales, el artículo se propone el estudio de los procedimientos empleados por este escritor para la narración de lo que hemos denominado como microtexto de la «poética del desamor» entendido como efecto contrario al producido por la plenitudo amoris. Se analiza, de este modo, la categoría emocional de la Tristitia y las series poéticas comprendidas en los campos semánticos centrados en el dolor, el llanto y el deseo hiperbólico de muerte, con la intención de describir tales procesos y la interpretación particular que el poeta hace de los mismos.Palabras clave: Boccaccio, Rimas, Desamor, Análisis textual.Abstract: Giovanni Boccaccio’s Rhymes can be analyzed by establishing certain thematic nuclei that allow a study of this work from both the macrotextual and the micro-textual approaches. Based on this assumption, this article will examine the procedures used by this writer for the narration of what we have defined as a micro-text of the «poetics of disaffection», to be considered as an effect opposed to that produced by the plenitudo amoris. Thus, the emotional category of the Tristitia and the poetic series included in the semantic fields of pain, weeping and the hyperbolic desire of death are analyzed, with the aim of describing such processes and the poet’s interpretation of the same.Keywords: Boccaccio, Rhymes, Disaffection, Textual analysis.
«Sobre los occidentales morfosintácticos y léxicos en las Profecías de Merlín en los Baladros castellanos»
Authors: Casais Alejandro
Published: November 2020

Resumen: El artículo tiene como objetivo completar una línea de trabajo dedicada al rastreo y el análisis de los occidentalismos (esto es, rasgos dialectales occidentales) de una traducción castellana de las Prophetiae Merlini de Godofredo de Monmouth interpolada en los Merlines de la Post-Vulgata ibérica (Baladro 1498 y Demanda 1535). Puesto que la primera parte de esta investigación estuvo consagrada a los occidentalismos fonéticos, nos enfocaremos ahora en los morfosintácticos y léxicos; comentaremos un ejemplo del primer grupo y diez del segundo. Volveremos a prestar atención tanto a los occidentalismos evidentes, esto es, los que aún se manifiestan abiertamente en los testimonios, como a los conjeturales, los que pueden entreverse tras sus errores. Estamos convencidos de que esta clase de estudio puede efectuar aportes de interés para una mejor comprensión de la historia textual de los Merlines castellanos.Palabras clave: Godofredo de Monmouth, Prophetiae Merlini, Traducción castellana, Baladro del sabio Merlín, Occidentalismos morfosintácticos y léxicos.Abstract: The article aims to complete a research dedicated to trace and analyse the occidentalismos (i.e., Western Dialectal Forms) of a Castilian translation of the Prophetiae Merlini by Geoffrey of Monmouth interpolated in the Merlines of the Iberian Post-Vulgate cycle (Baladro 1498 and Demanda 1535). Since the first part of this investigation was devoted to the phonetic occidentalismos, we will now focus on the morphosyntactic and lexical ones; we will discuss one example of the first group and ten from the second one. We will again pay attention both to the evident occidentalismos, those that are still openly present in the witnesses, as well as to the conjectural ones, those that can be glimpsed through their errors. We are convinced that this kind of study can make contributions of interest to a better understanding of the textual history of the Castilian Merlines.Keywords: Geoffrey of Monmouth, Prophetiae Merlini, Castilian Transla- tion, Baladro del sabio Merlín, Morphosyntactic and Lexical Occidentalismos (i.e., Western Dialectal Forms).
«La Historia de Inglaterra de Rodrigo de Cuero: fuentes y elaboración»
Authors: Contreras Martín Antonio , Soriano Robles Lourdes
Published: November 2020

Resumen: La Crónica de Inglaterra de Rodrigo de Cuero es una traducción de la Cronycle of Englonde with the Fruyte of Tymes realizada a instancias de Catalina de Aragón, reina de Inglaterra, en 1509. Mandada completar por ésta hasta su llegada a Inglaterra, el traductor tuvo que echar mano de las fuentes más diversas. El trabajo analiza, en primer lugar, qué fuentes empleó Rodrigo de Cuero para la elaboración de su obra; en segundo lugar, se ocupa de cómo organizó el material y confeccionó las dos versiones conservadas (manuscritos Escorial y Salamanca); y, en tercer y último lugar, se centra en el tratamiento de los reyes ingleses anteriores a Enrique VIII y Catalina de Aragón (Enrique VI, Eduardo IV, Eduardo V, Ricardo III y Enrique VII).Palabras clave: Historia de Inglaterra, Rodrigo de Cuero, Cronycle of Englonde, Catalina de Aragón, 1509, Traducciones, Historiografía.Abstract: Rodrigo de Cuero’s Historia de Inglaterra is a translation into Castilian of the Cronycle of Englonde with the Fruyte of Tymes made at the request of Catherine of Aragon, Queen of England, in 1509. Asked with the responsibility of completing the chronicle until her arrival at England, the translator had to draw on the most diverse sources. The paper analyses, firstly, what sources Rodrigo de Cuero used for the elaboration of his work; secondly, it deals with how he organized the material and made the two preserved versions (Escorial and Salamanca manuscripts); and, thirdly and last, it focuses on the treatment of the English kings before Henry VIII and Catherine of Aragon (Henry VI, Edward IV, Edward V, Richard III and Henry VII).Keywords: Historia de Inglaterra, Rodrigo de Cuero, Cronycle of Englonde, Catherine of Aragon, 1509, Translations, Historiography.
De grant mal amaladis e la pastorella nascosta in Aucassin et Nicolette: una proposta di datazione della chantefable
Authors: Spetia Lucilla
Published: November 2020

L’anonima chantefable Aucassin et Nicolette, fondata sulla parodia, ha una controversa datazione. Tuttavia la presenza di l’autrier – marca lessicale identificativa del genere pastorella –, e una serie di allusioni erotiche autorizzano a rileggere con maggiore attenzione il cap. XI, e inparticolare il v. 21 che riproduce il v. 12 del prologo, a conferma della centralità della scena rappresentata, in connessione sia con la lirica del gattorosso di Guglielmo IX, sia con la pastorella maggiore di Marcabruno ad essa connessa. Non solo, ma l’analisi lessicale di un altro vocabolo dello stesso capitolo consente di cogliere un ulteriore gioco intertestuale con le Jeu de la Feuillée di Adam de la Halle, che fornisce il 1276 come terminus post quem per la datazione della chantefable e di porre la sua composizione nell’ambiente borghese di Arras, di cui condivide le istanze sociali e culturali declinate attraverso il ricorso alla parodia.
Changed reactivity of secondary hydroxy groups in C8-modified adenosine – lessons learned from silylation
Authors: Frommer Jennifer , Müller Sabine
Published: November 2020

Synthesis of site-specifically modified oligonucleotides has become a major tool for RNA structure and function studies. Reporter groups or specific functional entities are required to be attached at a pre-defined site of the oligomer. An attractive strategy is the incorporation of suitably functionalized building blocks that allow post-synthetic conjugation of the desired moiety. A C8-alkynyl-modified adenosine derivative was synthesized, reviving an old synthetic pathway for iodination of purine nucleobases. Silylation of the C8-alkynyl-modified adenosine revealed unexpected selectivity of the two secondary sugar hydroxy groups, with the 3'-O-isomer being preferentially formed. Optimization of the protection scheme lead to a new and economic route to the desired C8-alkynylated building block and its incorporation in RNA.
Statistical analysis of the social and economic development of Ukrainian regions
Authors: POSHYVALOVA Olena , PROSHKINA Polina
Published: November 2020

The issue of the country's socio-economic development and analysis of its dynamics arises within the context of the transition to a market economy. The aim of the research is to consider the state of socio-economic development of the regions of Ukraine on the basis of the generalized multicriteria indicator, cluster analysis, as well as the multidimensional nonlinear regression model. To trace the presence of differentiation in the socio-economic development of the regions of Ukraine is especially important. The analysis implemented in the Thesis covers the widest range of indicators of the socio-economic condition of the regions of the country. An integral indicator of the socio-economic condition of the subjects of Ukraine has been offered as the main characteristic. The state statistical data have been used to construct a generalizing indicator. Ranking, as well as clustering of the country regions according to the selected indicators, makes it possible to more accurately determine which of them are the most developed. A multidimensional nonlinear model for forecasting the level of income of the Ukrainian population has been constructed on the basis of correlation and regression analysis. Conducting a comparative assessment of the socio-economic development of Ukrainian regions using integral indicator methods and cluster analysis, made it possible to identify a group of regions of Ukraine with a similar combination of feature values, as well as to determine the place and role of each of them in the national economy. This is of great importance for the development of the most crucial target programs for the economy, investment directions, and state support of lagging regions. The correlation regression model constructed has made it possible to identify the factors of the greatest impact on the change of population income levels, to determine the absolute and relative influence of the factors on the output indicators, and also to provide a reliable estimate of the future level of the output indicator, taking into account various conditions of the country's socio-economic development.
COPING MECHANISM DURING COVID- 19
Authors: Shukla Awa
Published: November 2020

In last almost more than 70 days of lockdown we all are observing entire / complete change in the Lifestyle of people from its roots. We all need to understand that; there is different impact in all the different classes of the society.The higher class society is staying at home with all fulfilled necessities and facilities at home. They have different ways to keep themselves engaged throughout the day as they do not face any kind of financial crisis.The other category is the middle class; which is the largest group of Indian society. This is the main group which is suffering from the other effects of corona; in my opinion.Whereas the third category is economically lower society which residence in the slams where we find over crowd, small houses, no facilities, unhygienic area, and life in a small corner of this earth.In this way, Covid- 19 has affected society differently - social, physically and mentally. The social impact is found very different.Corona has raised many questions individually, socially as well as nationally.It is very sad to see the way Media highlights the news of corona.Now with the changing time we all have accepted the New normal work pattern. We are back to work with safety practices, social distancing and more of virtual work which is entirely a different way of working.India is emerging as one of the youth empowered and innovation initiator Nation.
COMPARISON STUDY OF ONLINE EDUCATION PLATFORM
Authors: Patel Atul , Parekh Yogesh
Published: November 2020

With a boom in increased usage of internet, online learning has also witnessed a
tremendous growth in this era. Although the teaching pedagogy will vary from
platform to platform, the students and society at large have benefitted from vast
content in various formats, and they have experienced best learning through elearning. Various forms of electronic media support this e-teaching and learning
process. In this process, educational content is delivered over the web in the form of
text, video, audio format and fulfills the need of an instructor or trainer. This paper
analyses the teaching pedagogy, content and various other aspects of e-learning
platforms like SWAYAM, eDX and CourseEra.
O Antigo Paço Episcopal de Elvas: as Artes Decorativas e o seu percurso no contexto da I República
Authors: Cruz Grancho Nuno
Published: November 2020

A criação do novo bispado de Elvas no século XVI, exigia a construção de um Paço Episcopal que servisse de residência a todos os bispos que futuramente governassem a diocese. A sua construção, ampliação, e os muitos enriquecimentos empreendidos por alguns desses eclesiásticos, idealizados e concretizados de acordo com o gosto vigente, permitiu atribuir às suas casas uma atmosfera compatível com o estatuto inerente ao desempenho do seu cargo. A extinção da diocese em 1881 e a sua execução no ano seguinte, ditariam novas funcionalidades a este edifício, encontrando-se na Lei da Separação o momento histórico em que uma significativa parte da sua componente artística – pintura, mobiliário, ourivesaria, faiança, paramentaria, azulejaria, livraria, etc – se dispersa por inúmeras instituições culturais.
Notas para uma biografia de Luís Augusto de Parada e Silva Leitão (1811-1858)
Authors: Ferreira Queiroz José Francisco
Published: November 2020

Neste trabalho, apresentamos uma primeira tentativa de esboço biográfico de Luís Augusto Parada e Silva Leitão (1811-1858). Litógrafo, desenhador, engenheiro condutor de obras e professor de Desenho, Luís Augusto Parada e Silva Leitão viveu em Lisboa, em Coimbra e no Porto, constituindo um exemplo interessante de mobilidade e de versatilidade, com uma actividade que combinava a arte e a indústria.
Rethinking Frames in Contemporary Azulejo
Authors: Leitão Inês
Published: November 2020

This essay’s primary objective is to rethink the use of frames in contemporary azulejo by presenting how artists have been approaching this subject, whether to rescind of frames or to use them. In order to achieve this goal we present six case studies, three of which focus on no framing as way to blend azulejo coverings in its urban environment, whereas the others demonstrate how the artists use frames in order to contemporarily reinterpret azulejo traditions.
Early façade azulejo frames by Fábrica Roseira of Lisbon
Authors: Mimoso João Manuel
Published: November 2020

The paper reviews the importance and distinguishing character of façade azulejo frames as used in the region of Lisbon and presents and discusses the early frame patterns designed and produced by Fabrica Roseira in the mid-19th century.
Não desapareceu e está em sítio digno: a extinção das ordens religiosas e a redescoberta da tábua quinhentista atribuída a Gregório Lopes, outrora no Convento de Santo António da Piedade de Évora
Authors: Duarte Sónia
Published: November 2020

O trabalho de levantamento, estudo e disseminação nacional de centenas de imagens de música na pintura retabular quatrocentista e quinhentista portuguesa, e de outras com ligações a Portugal, não apenas nas obras vivas e memoriadas mas também naquelas de que pouco ou nada se achava escrito, permitiu-me reunir um corpus de mais de oito dezenas de pinturas, entre elas, uma Natividade atribuída ao pintor régio Gregório Lopes, cujo paradeiro redescobri em novembro de 2010.
O retrato do Infante D. Fernando nas Janelas Verde (M.N.A.A.)
Authors: Vaz Pacheco Maria Emília
Published: November 2020

«[...] uos certifico que nom perdemos a boa esperança de aiuda e acorrimento de Nosso Senhor Deus e da Virgem Maria, sua madre, Nossa Senhora e (...) em uos, ssenhor irmão, que sei que me tendes tamanho amor, que maior ser nom pode, e espero que, por me liurardes, fazeis e fareis como por uos mesmo». – Excerto da Carta do Infante Santo ao Regente D. Pedro, datada da Masmorra de Fez a 12 de Junho de 1441.

Palavras comoventes, rondando o desespero de quem, a dois anos da sua morte, não vislumbrava o modo como haveria de ser libertado, porventura porque consciente do real significado do seu cativeiro.
A propósito de três itens de Inventário
Authors: Machado Ana Paula
Published: November 2020

Em junho de 1834, chegava ao Museu Portuense uma das mais controversas incorporações na Fazenda Nacional, de entre as que os decretos liberais determinaram. Provenientes do Mosteiro de Santa Cruz de Coimbra, recolhiam ao Museu uma escrivaninha italiana, uma série de placas de esmalte pintado e a célebre espada de D. Afonso Henriques. Em parte devido à aura mítica desta última, ao longo dos cem anos seguintes, nestas três peças parecem ter confluído todos os argumentos da polémica integração dos bens das ordens religiosas e do pensamento e acção dos liberalistas sobre o Património. Este estudo propõe-se seguir mais de perto os destinos dessas três peças e compreender em que medida esses destinos extravasam ou configuram um paradigma dos de tantas outras, como elas, chegadas aos museus no “torvelinho das violentas paixões” da época.
O marquês de Sousa Holstein e a formação da Galeria Nacional de Pintura da Academia de Belas-Artes de Lisboa
Authors: Xavier Hugo
Published: November 2020

Neste texto definimos e sintetizamos algumas ideias centrais da Galeria Nacional de Pintura da Academia de Belas-Artes de Lisboa, da formação do seu acervo a partir de 1834, com a extinção das ordens religiosas, até à abertura do Museu Nacional de Belas Artes e Arqueologia, em 1884. Em análise estão 50 anos de esforços empreendidos por vários agentes, com destaque para o marquês de Sousa Holstein, vice-inspetor da Academia, em prol da organização, conservação, exposição, estudo, promoção e divulgação do seu acervo, assim como do seu enriquecimento por meio de transferências, aquisições ou doações que estão na origem do mais relevante museu público de arte nacional.
O restauro das pinturas conventuais guarda da Biblioteca Nacional (1835-1913). Contributos para a história da conservação e restauro
Authors: Moura Soares Clara , Massano Rodrigues Rute
Published: November 2020

A Real Biblioteca Pública da Corte, depois Biblioteca Nacional de Lisboa, desempenhou importantes funções na inédita estrutura de gestão do património, montada pelo Estado Liberal, destinada a «arrecadar, classificar, inventariar e conservar» milhares de peças, sobretudo de pintura, provenientes dos conventos extintos em 1834.

As preocupações com a conservação e restauro das obras que foram ficando à sua guarda, manifestaram-se em diversos momentos, reflexo das sensibilidades dos sucessivos diretores da instituição. As intervenções de restauro, realizadas por diversos protagonistas, entre 1835 e 1913, espelham a evolução de princípios na matéria, mas sobretudo o valor histórico de que foi beneficiando aquele acervo pictórico, em detrimento da sua valorização artística.
The Post-Internet Condition
Authors: Teixeira Pinto Ana , Franke Anselm
Published: November 2020

Throughout the modern period, the multivalence of the concept of media has extended beyond the technological field, to include aesthetic and spiritual registers. This paper will attempt to address the transition to digital media, widely known as the digital turn, in terms of what we will refer to as the post-internet “mode of representation,” and the “truth-effects” it engenders.
Resgate das Obras Mortas de Pintura “Animalista” de Bernardino da Costa Lemos (175?-act.1814)
Authors: Costa Ana Maria , Serrão Vítor , Mendonça de Carvalho Luís
Published: November 2020

Existiam lacunas de informação sobre o presumível desaparecimento de 11 quadros “animalistas” de Bernardino da Costa Lemos no trágico incêndio ocorrido em 1978 na Faculdade de Ciências da Universidade de Lisboa. Excluindo o artigo de Júlio Jesus (1928) com descrições écfrasicas-histórico-artísticas de cada uma das telas, cinquenta anos antes delas desaparecerem, Lemos subsiste na generalidade da historiografia como um modesto pintor que floresceu em final de setecentos, discípulo de Joaquim Manuel da Rocha. A localização de documentos e registos imagéticos totalmente desconhecidos da obra “animalista” de Lemos impôs uma abordagem interdisci­plinar de História da Arte (micro e cripto-história da arte, iconologia), Literatura (ekphrasis) e Biologia (ecologia e taxonomia). Assim, neste artigo visitamos visualmente as referidas obras mortas, revemos a biografia do “muito hábil” pintor, confirmamos o malogrado destino do conjunto e discutimos sobre a tipologia de programa artístico produzido para o Gabinete de História Natural do mecenas Frei José Mayne.
O retrato pouco consentido de Francisco Pérez Bayer, por Manuel José Pinheiro, na pinacoteca de D. Frei Manuel do Cenáculo
Authors: Da Cruz Leal Lécio
Published: November 2020

Da passagem de Francisco Pérez Bayer por Portugal, em 1782, resultou o seu retrato, aliás, uma «simples lembrança» sua, hoje integrada nas reservas do Museu de Évora e proveniente da pinacoteca de D. frei Manuel do Cenáculo. A colecção de pintura do bispo vinha sendo reforçada com a encomenda de retratos de figuras edificantes da sociedade. Integrava-se num vasto projecto educativo de natureza iluminista, configurado numa biblioteca-museu, servindo os retratos de monumento celebrativo e estimulante do homem exemplar, civilizado ou moral e das suas multifacetadas inteligências. A figura de Pérez Bayer enquadrava-se perfeitamente na galeria do então bispo de Beja e por isso agilizou-se a encomenda e incorporação do seu retrato, tendo sido apenas agora redescoberto no acervo do Museu de Évora, isto depois de mais de um século mal identificado, tratando-se da primeira obra conhecida do pintor Manuel José Pinheiro.
Giuseppe Trono, Pintor de retratos na corte Portuguesa (1785-1810)
Authors: Raggi Giuseppina , Degortes Michela
Published: November 2020

A vasta obra do artista italiano Giuseppe Trono (Turim, 1739 – Lisboa, 1810), como retratista da corte portuguesa em finais de século XVIII, reveste-se de grande importância na construção e divulgação da imagem da família real, numa dinâmica de produção que abrange o âmbito de gravuras e miniaturas. Trono realizou também retratos da elite dos aristocratas e fidalgos lusitanos, onde foi adquirindo fama como pintor e miniaturista. O painel da capela do palácio da Bemposta, um extraordinário conjunto de retratos da família real e do povo lisboeta, representa, através duma complexa iconografia, as políticas do governo de D. Maria I à luz da sua identificação com o culto do Sagrado Coração de Jesus configurando-se como um caso único no contexto artístico português.
The Latin American liberator Simón Bolívar at the Museum of Art in Bogotá, Colombia: ten images by five artists
Authors: Arreaza Scrocchi Rafael
Published: November 2020

This review compiles and analyzes a set of ten images related to the Latin-American Liberator, Simón Bolívar,that were never published as a single study. These ten portraits re-imagined by five different artists: José María Espinoza (1796-1883); Henry Riballier (1802-1889); W. Holl - M. N. Bate (1807-1871); Sergio Trujillo Magnenat (1911-1999); and Carlos García Arango (1930-2002), remain archived at the Museum of Art of the Bank of the Republic of Colombia in Bogotá. This study describes and explains the distinct motifs that are depicted in all of these reinterpretations of the image of Simón Bolívar.
Os Arquitectos e a direcção das campanhas decorativas com azulejos
Authors: Mangucci Celso
Published: November 2020

Apesar de pouco conhecida e estudada, a participação dos arquitectos é fundamental para a definição do papel específico que a azulejaria desempenha em cada campanha decorativa. Nesse âmbito, a actividade do arquitecto é, em larga medida, o de supervisor geral da obra, podendo ser o responsável pelo desenho de pormenor do programa decorativo, pela compatibilização entre as diversas artes e o discurso arqui­tectónico, pela indicação de matérias ou técnicas construtivas especificas para o azulejo, ou ainda, pela supervisão do desenvolvimento das diversas fases da obra e pelos pagamentos aos mestres envolvidos. Por concentrar em si o poder efectivo das decisões é também o interlocutor privilegiado dos encomendadores, podendo ainda delegar em pintores e mestres ladrilhadores a formalização de desenhos de pormenor.
A Arte do Azulejo em Portugal nos séculos XVII-XVIII: à (Re)descoberta dos seus Mestres
Authors: Portela Miguel
Published: November 2020

Pretendemos, com este estudo, dar a conhecer elementos da maior relevância para o percurso da vida e obra de alguns mestres ligados à arte da azulejaria em Portugal, em particular, dos ladrilhadores António de Abreu, Domingos da Cruz, Manuel da Mata, Pedro de Almeida, Matias Batista Lisboa, Dionísio de Araújo, e dos oleiros Manuel dos Santos e Miguel de Azevedo.

Procuraremos, ainda, elencar documentos que nos permitem traçar o seu percurso familiar, assim como alguns acontecimentos do seu caminho profissional e artístico, entre o final do século XVII e as primeiras décadas do século XVIII.

Por fim, propomo-nos, através de um conjunto de novos dados, alargar o conhecimento sobre estes mestres ladrilhadores, oleiros e pintores de louça no contexto do Ciclo dos Mestres, firmando e dando consistência e rigor aos elementos elencados que nos permitiram (re)descobrir a arte da azulejaria em Portugal nesse período.
O problema da autoria e da repartição de tarefas na Produção Azulejar do Período Romântico
Authors: Queiroz Francisco
Published: November 2020

A produção azulejar do período Romântico em Portugal tem merecido um crescente interesse nos últimos anos, mas o problema da autoria e da repartição de tarefas tem sido praticamente ignorado na produção científica existente sobre esse período. Neste texto é apresentado o estado da arte sobre a questão.
‘Vivendo de sua fazenda e da sua arte de pintor´: relações entre as imagens de música e a vila de Borba, a partir da obra pictórica de José de Sousa de Carvalho (1741-1795)
Authors: Duarte Sónia
Published: November 2020

Pintor, escultor e proprietário, integrado numa elite borbense, José de Sousa de Carvalho (1741 — 1795) é o autor de várias pinturas que se espalham por espaços públicos e privados, incluindo as raríssimas representações musicais e de dança que se guardam nos Paços do Concelho de Borba. Pai de Bernardo Germano de Carvalho (1777 — 1853), também pintor e proprietário, e avô paterno de José Ignácio de Carvalho (1819 — 1887), coris­ta na Igreja Matriz de Borba e capelão na Colegiada da Misericórdia de Borba, Sousa de Carvalho documenta, em oito telas que pinta de visu — para decorar, com grande probabilidade, a sua residência familiar, o Palacete dos Sousa Carvalho e Melo –, momentos de recreio da escol borbense inerentes ao gosto coevo, aos hábitos domésticos de sociabilidade crescente, e à grandeza e poder de uma família telúrica endinheirada. Em contexto, deixaremos breves achegas para a vida musical borbense entre finais do século XVII e o início do século XIX, incluindo notas inéditas relativas ao, até agora, desconhecido Pedro Gonçalves Mexia.
The 1951 Diplomatic gift: the role of a Germain eighteenth century Hanukkah Lamp in Israeli-American relations
Authors: Kochavi Shir
Published: November 2020

A diplomatic gift in the form of a Hanukkah Lamp, given to President Harry Truman by the Prime Minister of Isra­el, David Ben-Gurion in 1951 was selected for this occasion by museum personnel from the Bezalel Museum in Jerusalem and the Jewish Museum in New York. Based on primary sources found in archives in Israel and in the United States, this case study investigates the process of objects exchange between two museums, orchestrated on the basis of an existing collegial relationship, and illustrates how the Hanukkah Lamp becomes more than itself and signifies both the history of the Jewish people and the mutual obligations between the two nations. Drawing on the theories of Marcel Mauss, Arjun Appadurai, and Igor Kopytoff on the notion of the gift, the article highlights the layers of meanings attributed to a gifted object.
Identidades Frente al Espejo: Azulejos en Portugal y Valencia
Authors: Jaume Coll Conesa
Published: November 2020

La Península Ibérica posee en Portugal y Valencia dos áreas en las que la azulejería ha jugado un papel relevante a través de la historia. Ambos territorios la flanquean al Este y al Oeste, por lo que parecen proyectarse en una imagen especular aunque cada uno de ellos posee una personalidad distintiva y singular, a veces convergente y a veces divergente, que permiten su comparación para encontrar sintonías, diferencias o especificidades propias de cada uno de estos focos de irradiación universal del azulejo.
“Excellentes Reproducções de Trabalhos Antigos em Marfim”. Os Fuctile Ivories do Museu Nacional de Arte Antiga
Authors: Das Neves Afonso André
Published: November 2020

As reproduções de objetos artísticos em gesso, galvanoplastia ou fotografia assumiram-se como instrumentos fundamentais no quadro da museologia da segunda metade do século XIX, mais especificamente no contexto das práticas colecionísticas, expositivas e pedagógicas dos museus de artes ornamentais, industriais ou decorativas. A Academia Real de Belas-Artes de Lisboa (ARBAL) formará coleções desta natureza, seja para fins de ensino académico ou fins museológicos. No presente texto debruçar-nos-emos em torno de uma coleção inédita de trinta e duas peças em gesso que reproduzem placas de marfi m esculpido – os designados fictile ivories –, atualmente no acervo do Museu Nacional de Arte Antiga (MNAA), e que resultam de uma importante oferta do South Kensington Museum de Londres, em 1866, à Academia Real de Belas-Artes de Lisboa. Analisaremos o fenómeno da importância internacional das reproduções, a oferta realizada pelo museu londrino, a especificidade dos fictile ivories neste âmbito e, considerando as limitações de uma investigação ainda em curso, apresentaremos alguns dados de caraterização desta coleção.
The Image of Art between Ideology and Modernity. Elblag Biennales of Spatial Forms in 1960’s Poland
Authors: Błotnicka-Mazur Elżbieta
Published: November 2020

In 1965 Gerard Kwiatkowski and Marian Bogusz organized the first of the Spatial Forms Biennales in Elbląg – a city based in the so-called “Recovered Territories”. Selected artists, supported by ZAMECH mechanical plant and with the permission of the communist authorities, created several dozen huge metal sculptures known as “Spatial Forms”. This was the biggest experiment combining art and industry in Poland or even in Europe. The aim of the article is to juxtapose the role of this phenomenon, namely how the creators of the Biennales found a balance between artistic freedom and political limitations, these limitations were forced upon the artists in a way that might prompt one to recall, Foucault’s manner of “discipline” (Foucault, 1973). The author of the article also touches upon the question of the contemporary view of the Elbląg Biennale from the perspective of the avant-garde myth of social and collective participation in artistic creation.
Dois Retratos de Abel Manta
Authors: Rodarte Veloso Carlos
Published: November 2020

Duas telas inéditas de Abel Manta (1888-1982), pintor modernista português, representando o Engº Celestino Rodarte de Almeida e sua fi lha, Maria Julieta Rodarte de Almeida Veloso.
Current Screening Strategy Poses Risk of Spreading of Hepatitis C Virus Infection
Authors: Ullah Sajjad , Ahmad Sohail , Ali Qaisar , Jamal Arshad , Yousaf Muhammad Zubair , Waqar Ahmed Bilal
Published: November 2020

Background: Hepatitis C virus is one of the significant causes of morbidity and mortality in the World. Surprisingly, despite national screening campaigns, new cases of HCV are still on the rise.
Methods and Results: A total of 5914 healthy blood donors was included in this study after informed consent. Anti-HCV ELISA was used to check presence of antigen in participant’s plasma.using Monlisa HCV Antigen-Antibody Ultra kit. Final confirmation was done by using real time PCR considered as a gold standard.
Results: 0.5% of anti-HCV ELISA negative samples showed presence of antigen in plasma, when checked through core Ag detection method.
Conclusion: Our result suggested that HCV core antigen detection and/or combo testing are far safer screening methods for the detection of HCV and the use of these methods can avoid/reduce further spread of this deadly disease.
Establishing Earth’s Minimoon Population through Characterization of Asteroid 2020 CD3
Authors: Fedorets Grigori , Micheli Marco , Jedicke Robert , Naidu Shantanu P. , Farnocchia Davide , Granvik Mikael , Moskovitz Nicholas , Schwamb Megan E. , Weryk Robert , Wierzchoś Kacper , Christensen Eric , Pruyne Theodore , Bottke William F. , Ye Quanzhi , Wainscoat Richard , Devogèle Maxime , Buchanan Laura E. , Djupvik Anlaug Amanda , Faes Daniel M. , Föhring Dora , Roediger Joel , Seccull Tom , Smith Adam B.
Published: November 2020

We report on our detailed characterization of Earth’s second known temporary natural satellite, or minimoon, asteroid 2020 CD3. An artificial origin can be ruled out based on its area-to-mass ratio and broadband photometry, which suggest that it is a silicate asteroid belonging to the S or V complex in asteroid taxonomy. The discovery of 2020 CD3 allows for the first time a comparison between known minimoons and theoretical models of their expected physical and dynamical properties. The estimated diameter of

m and geocentric capture approximately a decade after the first known minimoon, 2006 RH120, are in agreement with theoretical predictions. The capture duration of 2020 CD3 of at least 2.7 yr is unexpectedly long compared to the simulation average, but it is in agreement with simulated minimoons that have close lunar encounters, providing additional support for the orbital models. 2020 CD3's atypical rotation period, significantly longer than theoretical predictions, suggests that our understanding of meter-scale asteroids needs revision. More discoveries and a detailed characterization of the population can be expected with the forthcoming Vera C. Rubin Observatory Legacy Survey of Space and Time.