bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Different Rearing Systems on Lueyang Black-Bone Chickens: Meat Quality, Amino Acid Composition, and Breast Muscle Transcriptome
Authors: Zhang Shuya , Zhang Jiqiao , Cao Chang , Cai Yingjie , Li Yuxiao , Song Yiping , Bao Xiuyu , Zhang Jianqin
Published: October 2022

The quality of poultry products depends on genotype, rearing system, and environment. The aim of this study was to investigate the effects of different rearing systems on meat quality, amino acid composition, and breast muscle transcriptome from Lueyang black-bone chickens. Lueyang black-bone chickens (n = 900) were randomly divided into three groups (cage, flat-net, and free-range groups), with three replicates per group (100 chickens per replicate). At 16 weeks, a total of 36 healthy chickens (six males and six females per group) were collected, and their breast muscles were sampled to detect meat quality parameters, amino acid composition, and fatty acid contents. Furthermore, breast muscles from six random hens in each group were used for RNA-seq analysis. The results revealed that the values of pH, shear force, inosine monophosphate (IMP), palmitic acid, and linoleic acid in the free-range group were significantly higher than those in the caged group (p < 0.05). Fat content in the free-range group was significantly lower than in the caged and flat-net groups (p < 0.05). Glutamate (Glu) levels, the amino acid crucial for the umami taste, was significantly higher in the free-range group than in the caged group (p < 0.05). Meanwhile, there was no significant difference between the free-range and flat-net groups (p > 0.05). The breast muscle transcriptome results showed that there were 291, 131, and 387 differently expressed genes (DEGs) among the three comparison groups (caged vs. free-range, flat-net vs. caged, and flat-net vs. free-range, respectively) that were mainly related to muscle development and amino acid metabolism pathways. To validate the accuracy of the transcriptome data, eight genes (GOS2, ASNS, NMRK2, GADL1, SMTNL2, SLC7A5, AMPD1, and GLUL) which relate to fat deposition, skeletal muscle function, and flavor formation were selected for Real-time Quantitative PCR (RT-qPCR) verification. In conclusion, these results suggested that rearing systems significantly influenced the meat quality and gene expression of Lueyang black-bone chickens. All the data proved that free-range and flat-net systems may provide better flavor to consumers by affecting the deposition of flavor substances and the expression of related genes. These findings will provide a valuable theoretical basis for the rearing system selection in the poultry industry.
Insecticidal Activity against Myzus persicae of Terpinyl Acetate and Bornyl Acetate in Thuja occidentalis Essential Oil
Authors: Song Hyun-Jin , Yong Seong-Hyeon , Kim Hak-Gon , Kim Do-Hyun , Park Kwan-Been , Shin Keum-Chul , Choi Myung-Suk
Published: October 2022

Essential oils have insecticidal activity against several insects and are composed of numerous compounds. This study investigated the insecticidal effects of the Thuja occidentalis L. (Cupressaceae) essential oil, terpinyl acetate, and bornyl acetate against the peach aphid [Myzus persicae (Sulzer)]. The insecticidal effect of essential oils on three Cupressaceae plants was highest in T. occidentalis. The Thuja occidentalis essential oil was extracted by steam distillation, and the optimum conditions were found. The GC-MS profiling of essential oil components extracted from T. occidentalis leaves identified 16 volatile compounds. The main components were α-thujone (16.58%), β-myrcene (14.62%), bornyl acetate (9.31%), and terpinyl acetate (8.52%). As a result of the metabolite profiling of three Cupressaceae plants, terpinyl acetate and bornyl acetate were present in large amounts in all of the essential oils, and they had an acetate structure, so it was estimated that they had insecticidal activity. The insecticidal activity of these two compounds was stronger than the other individual monoterpene compounds. The addition of surfactants to the terpinyl acetate and bornyl acetate showed strong insecticidal activity. Terpinyl acetate and bornyl acetate can be used as environmentally friendly insecticidal-active compounds.
Effects of Molybdenum Fertilizer Combined with Bacillus subtilis Strain on the Growth of Chinese Cabbage and the Content of Nitrate in Soil
Authors: Ma Yao , Zhang Siwen , Hu Jiawei , Chen Shiyong , Wang Juanjuan
Published: October 2022

With increasing nitrogen application in soil, the problem of nitrate accumulation in soil and vegetable bodies has become increasingly serious. In this study, Bacillus subtilis (B. subtilis) Strain11 was isolated and studied for its effects in combination with Molybdenum (Mo) on the growth of Chinese cabbage and soil nitrate content. The results showed that the strain effectively increased the growth, height, and moisture content of Chinese cabbage by 27% and 2.5%, respectively, compared to the control. Mo application alone reduced soil nitrate accumulation and increased root length, height, chlorophyll content, and moisture content of Chinese cabbage, with an optimal rate of 0.8–1.2 mg/kg soil. The application of Mo fertilizer in combination with the Bacillus strain was the most effective in increasing plant height and root length of Chinese cabbage, which were 1.49 times and 1.68 times that of the control, respectively. The proportion of dry matter, the average fresh weight, and the dry weight under this treatment were 9.01%, 5.83 g/plant, and 0.53 g/plant, respectively, higher than the rest. At harvest, the highest ammonium-nitrogen content in this treatment group was 8.56 mg/kg, and the soil nitrate reduction reached 40.68%. In conclusion, Mo fertilizer at a rate of 0.8 mg Mo/kg soil, in combination with B. subtilis Strain11, was recommended for the remediation of nitrate-contaminated soils.
Monitoring and Quantifying the Fluvio-Geomorphological Changes in a Torrent Channel Using Images from Unmanned Aerial Vehicles
Authors: Gkiatas Georgios T. , Koutalakis Paschalis D. , Kasapidis Iordanis K. , Iakovoglou Valasia , Zaimes George N.
Published: October 2022

The study attempts to monitor geomorphological changes (e.g., erosion/deposition) with innovative tools at a typical Mediterranean torrent. The torrent’s geomorphological conditions are studied for an entire affected stream reach. The investigation utilizes two different environments/point views: (a) traditional terrestrial and (b) innovative aerial. The traditional methods include erosion pins at streambanks and field cross-section measurements of the stream channel. For the innovative methods, utilizing an unmanned aerial vehicle, in order to monitor the geomorphologic changes in the entire reach during different days over the last 3 years (2020–2022), there was a total of six flights. The results from innovative methods showcase the episodic nature of stream channel changes since erosion and deposition were captured during the different monitoring periods. Even during one flight in one cross-section, the stream bed and two banks in many cases experienced different changes. The significant erosion and deposition recorded showcase the disequilibrium in the torrent. In addition, the impact of the anthropogenic structure (Irish bridge) is evident, since upstream, more substantial deposition was recorded compared to downstream. The similarity of the results between the innovative method and the traditional methods indicates the method’s effectiveness and the potential usefulness in using UAV images for stream bank and bed monitoring. One of the biggest advantages is the ability to monitor the entire reach at substantially lower costs and time compared to the traditional methods. Still, more testing needs to be conducted in different stream and river environments to better refine the method in order to be adopted by land and water managers to be used for stream and river monitoring.
Simulation of Vegetation Carbon Sink of Arbor Forest and Carbon Mitigation of Forestry Bioenergy in China
Authors: Ma Xiaozhe , Wu Leying , Zhu Yongbin , Wu Jing , Qin Yaochen
Published: October 2022

Mitigating carbon emissions through forest carbon sinks is one of the nature-based solutions to global warming. Forest ecosystems play a role as a carbon sink and an important source of bioenergy. China’s forest ecosystems have significantly contributed to mitigating carbon emissions. However, there are relatively limited quantitative studies on the carbon mitigation effects of forestry bioenergy in China, so this paper simulated the carbon sequestration of Chinese arbor forest vegetation from 2018 to 2060 based on the CO2FIX model and accounted for the carbon emission reduction brought about by substituting forestry bioenergy for fossil energy, which is important for the formulation of policies to tackle climate change in the Chinese forestry sector. The simulation results showed that the carbon storage of all arbor forest vegetation in China increased year by year from 2018 to 2060, and, overall, it behaved as a carbon sink, with the annual carbon sink fluctuating in the region of 250 MtC/a. For commercial forests that already existed in 2018, the emission reduction effected by substituting forestry bioenergy for fossil energy was significant. The average annual carbon reduction in terms of bioenergy by using traditional and improved stoves reached 36.1 and 69.3 MtC/a, respectively. Overall, for China’s existing arbor forests, especially commercial forests, forestry bioenergy should be utilized more efficiently to further exploit its emission reduction potential. For future newly planted forests in China, new afforestation should focus on ecological public welfare forests, which are more beneficial as carbon sinks.
Effects of Wearing FFP2 Masks on SARS-CoV-2 Infection Rates in Classrooms
Authors: Jarnig Gerald , Kerbl Reinhold , van Poppel Mireille N. M.
Published: October 2022

In this retrospective cohort study involving 614 secondary school students, the likelihood of becoming infected with SARS-CoV-2 in schools with different focus (sports focus vs. general branch; the only difference in the sports focus school was that PE was allowed at all times without restrictions) and different prevailing restrictions were compared. A significantly higher likelihood of infection with SARS-CoV-2 was found in sports classes during the period with a strict FFP-2 mask requirement compared to general branch classes (for Delta from November 2021 to December 2021, and for Omicron from January 2022 to February 2022). The higher likelihood of infection was observed both during the Delta and the Omicron wave. After the relaxation of the mitigation measures, however, students in general branch classes showed a clear “catch-up” of infections, leading to a higher incidence of infections during this phase. By the end of the observation period (30 April 2022), only a small difference in cumulative SARS-CoV-2 infection rates (p = 0.037, φ = 0.09) was detected between classes with a sports focus and those without a sports focus. The results suggest that SARS-CoV-2 transmission can be reduced in school classes by mandatory FFP-2 mask use. In many cases, however, infection appears to be postponed rather than avoided.
The Role of Social and Cultural Values in Pandemic Control in a Chinese Community: An Ethnographic Study on the Construction and Stigmatization of “Others” in Severe Acute Respiratory Syndrome (SARS) and COVID-19 in Hong Kong
Authors: Siu Judy Yuen-man
Published: October 2022

Background: Studies have widely reported that social and cultural values serve as constraints in controlling the spread of an epidemic. However, I argue that a social and cultural value system is a double-edged sword and can motivate people’s preventive health behaviors. Few studies have examined the positive role of social and cultural values in promoting epidemic control. Methods: Using the severe acute respiratory syndrome outbreak in 2003 and the COVID-19 pandemic that began in 2020 in Hong Kong as examples, the present study performed participant observation in Hong Kong from January to June 2003 and from January 2020 to May 2022; in-depth individual semi-structured interviews were conducted with 70 participants between February 2021 and March 2022. Results: Social and cultural values serve as informal social control mechanisms in manipulating people’s adoption of preventive health behaviors that can assist in epidemic control. Specifically, the construction and stigmatization of the “others” groups and the traditional cultural values based on the capitalist ideology were noted to facilitate control measures against the two outbreaks in Hong Kong. Conclusion: These two outbreaks reinforced the embedded social and cultural values of the capitalist ideology of Hong Kong, which increased the vulnerability of disadvantaged social groups to stigmatization.
Clusters of Pregnant Women with Severe Acute Respiratory Syndrome Due to COVID-19: An Unsupervised Learning Approach
Authors: Carneiro Isadora Celine Rodrigues , Feronato Sofia Galvão , Silveira Guilherme Ferreira , Chiavegatto Filho Alexandre Dias Porto , Santos Hellen Geremias dos
Published: October 2022

COVID-19 has been widely explored in relation to its symptoms, outcomes, and risk profiles for the severe form of the disease. Our aim was to identify clusters of pregnant and postpartum women with severe acute respiratory syndrome (SARS) due to COVID-19 by analyzing data available in the Influenza Epidemiological Surveillance Information System of Brazil (SIVEP-Gripe) between March 2020 and August 2021. The study’s population comprised 16,409 women aged between 10 and 49 years old. Multiple correspondence analyses were performed to summarize information from 28 variables related to symptoms, comorbidities, and hospital characteristics into a set of continuous principal components (PCs). The population was segmented into three clusters based on an agglomerative hierarchical cluster analysis applied to the first 10 PCs. Cluster 1 had a higher frequency of younger women without comorbidities and with flu-like symptoms; cluster 2 was represented by women who reported mainly ageusia and anosmia; cluster 3 grouped older women with the highest frequencies of comorbidities and poor outcomes. The defined clusters revealed different levels of disease severity, which can contribute to the initial risk assessment of the patient, assisting the referral of these women to health services with an appropriate level of complexity.
Preliminary Assessment of a Flexible Multi-Sensor Wearable System Based on Fiber Bragg Gratings for Respiratory Monitoring of Hemiplegic Patients
Authors: Zaltieri Martina , Massaroni Carlo , Di Tocco Joshua , Bravi Marco , Morrone Michelangelo , Sterzi Silvia , Caponero Michele Arturo , Schena Emiliano , Lo Presti Daniela
Published: October 2022

Respiratory diseases are common in post-stroke hemiplegic patients and represent a major social problem as they worsen the quality of life and reduce the life span. As a consequence, being able to monitor respiratory parameters such as the respiratory rate (RR) and assess the presence of respiratory asynchronies could be of paramount importance to define hemiplegics’ health status. Moreover, RR is a useful parameter to investigate the level of fatigue and distress that these patients undergo during rehabilitation processes. Although motion capture systems and flowmeters are the leading instruments for respiratory pattern evaluation, smart wearable systems are gaining ever more acceptance since they allow continuous monitoring by detecting chest wall breathing displacements, ensuring reduced costs and no need for dedicated spaces. Among other sensing technologies, fiber Bragg grating (FBG) sensors have emerged thanks to their high sensitivity to strain, lightness, and multiplexing capability. In this work, a wearable system composed of four flexible dumbbell-shaped sensing modules is proposed for respiratory monitoring in hemiplegic patients. The system is light and easy to wear and can be adapted to any anthropometry thanks to the modular anchoring system. Its feasibility assessment in RR evaluation was performed on seven hemiplegic volunteers in eupnea and tachypnea breathing conditions. In addition, an explorative investigation was conducted to assess the system’s ability to detect asynchronies between torso compartments. The good results suggest that this device could be a useful instrument to support clinicians and operators in hemiplegic patients’ management.
Not All That Glitters Is Gold: Attractive Partners Provide Joys and Sorrows
Authors: Cardelli Anna , Matera Camilla , Policardo Giulia Rosa , Di Gesto Cristian , Nerini Amanda
Published: October 2022

Through a 2 × 2 experimental vignette design, we tested if partner perceived attractiveness in interaction with appearance-related comments from one’s partner might affect women and men’s body dissatisfaction, body shame, acceptance of cosmetic surgery, and perceived relationship quality. Participants were 154 women and 157 men living in Italy (mean age = 30.97; all of them were in a couple relationship), who read a vignette describing the purchase of a swimsuit, through which partner attractiveness (poor versus high) and partner commentary (negative versus positive) were manipulated. Some ANCOVAs were performed on women and men separately. For men, partner commentary affected body dissatisfaction with low body fat. Moreover, the main effect of partner attractiveness was found in their consideration of undergoing cosmetic procedures. Among women, a significant partner attractiveness X partner commentary interaction effect emerged on acceptance of cosmetic surgery for social reasons. As regards relationship quality, for women, there was a main effect of partner attractiveness on relational communication, while a marginally significant interaction effect between partner attractiveness and partner commentary emerged for men’s self-disclosure. Our findings suggest that partner attractiveness is generally beneficial, but when combined with negative feedback concerning the appearance, it might lose its advantages. These findings should be considered for planning interventions aimed at both preventing body dissatisfaction and acceptance of cosmetic surgical procedures for not medical reasons and promoting relationship satisfaction among women and men.
A Parsimonious Taxonomy of The Newly Retired: Spousal and Disability Combinations Shape Part or Complete Retirement
Authors: Rodwell John , Hendry Thomas , Johnson Dianne
Published: October 2022

The inadequate classification of retiree sub-groups ultimately results in misaligned policy. To generate sets of sub-groups that may be appropriately targeted for policy and interventions, variables are used that reflect the social structure of retirees, particularly the options of partial and complete retirement, marital status, gender, as well as the retirement status of the spouse, where relevant, and disability. Three sets of longitudinal Australian data were combined, each reflecting a four-year period (2003–2007, 2007–2011, 2011–2015) during which the individuals aged 45 to 69 retired (n = 1179). A multiway frequency analysis was performed to develop an inductive, combinatorial model of retirement from work. The resulting parsimonious taxonomy of sub-groups of the newly retired reflected main effects and interactions of key social-structural variables. Notably, a key driver of the pattern of results was that couples tend to coordinate their retirement behavior in both the decision to retire and form of retirement. Non-partnered retirees were more likely to be women. Disability was also a driver of retirement for non-partnered retirees, regardless of gender. Identifying sub-groups based on combinations of retiree characteristics can better inform policy design, appropriate health promotion interventions and potential specific triggers for enacting those policies. Overall, marital status, spousal retirement behavior and disability may each present a more useful basis for a taxonomy of retirement than more individually oriented age- and wealth-based systems.
Promotion of Parenting and Mental Health Needs among Chinese Women Living in Japan: A Qualitative Study
Authors: Luo Yunjie , Sato Yoko , Zhai Tianyue , Kagamiyama Hiromi , Ebina Yasuhiko
Published: October 2022

Chinese women raising children in Japan tend to experience high parenting stress and poor mental well-being. However, their specific parenting and mental health promotion needs remain unknown. This study aimed to explore the parenting and mental health promotion needs of Chinese women living in Japan and provide recommendations to guide interventions. Semi-structured in-depth interviews were conducted. Participants included 15 women aged 28–39 years who were pregnant or rearing a child younger than six years old. Thematic analysis was performed for data analysis. More than half of the participants experienced mental health problems, such as depressive symptoms and child-rearing stress. Four themes relating to their needs were identified: concrete support, information provision, caring and understanding, and social network building. Information provision and social network building should be emphasized as practical social support mechanisms to improve these women’s mental health. Furthermore, a mental health promotion intervention should be developed to address this vulnerable population’s needs. Healthcare providers and public health workers should help improve the social support systems of Chinese women in Japan to prevent mental health problems. Potential transcultural education can, arguably, help healthcare providers better understand transcultural care.
Simulation-Based Education in Trauma Management: A Scoping Review
Authors: Larraga-García Blanca , Quintana-Díaz Manuel , Gutiérrez Álvaro
Published: October 2022

Trauma injuries are an important healthcare problem and one of the main leading causes of death worldwide. The purpose of this review was to analyze current practices in teaching trauma management using simulations, with the aim of summarizing them, identifying gaps and providing a critical overview on what has already been achieved. A search on the Web of Science website for simulation-based trauma training articles published from 2010 onwards was performed, obtaining 1617 publications. These publications were screened to 35 articles, which were deeply analyzed, gathering the following information: the authors, the publication type, the year of the publication, the total number of citations, the population of the training, the simulation method used, the skills trained, the evaluation type used for the simulation method presented in the paper, if skills improved after the training and the context in which the simulation took place. Of the 35 articles included in this review, only a few of them had students as the target audience. The more used simulation method was a high-fidelity mannequin, in which the participants trained in more technical than non-technical skills. Almost none of the studies introduced an automated evaluation process and most of the evaluation methods consisted of checklists or questionnaires. Finally, trauma training focused more on treating trauma patients in a hospital environment than in a pre-hospital one. Overall, improvements in the evaluation method, as well as in the development of trauma training on undergraduate education, are important areas for further development.
Do Age-Friendly Community Policy Efforts Matter in China? An Analysis Based on Five-Year Developmental Plan for Population Aging
Authors: Chu Yongqiang , Zhang Huan
Published: October 2022

(1) Background: The study will examine whether local governments’ policy efforts on age-friendly communities (AFC) promote older adults’ social participation in China. The extensive scope of AFC makes measuring policy efforts very challenging. The study attempts to introduce the developmental planning and goal-setting theory in public policy literature to answer this question. (2) Methods: We look at the Eleventh Five-Year Developmental Plan for Population Aging in subnational governments and CHARLS (the China Health and Retirement Longitudinal Study) baseline dataset from 2011, with data on policy strength and social participation of older adults. By using multilevel linear models, we regress social participation at the individual level on the policy strength of age-friendly communities at the provincial level. (3) Results: The results show that policy strength on AFC does vary substantially among provinces within China. And the interaction between policy strength of physical environment of local governments and community infrastructures is positively associated with social participation of rural older adults in China. (4) Conclusions: We conclude that policy efforts of local governments on the physical environment of age-friendly communities have effectively promoted the social participation of rural older adults in China. Policy makers could integrate physical infrastructures into their rural revitalization strategy to improve the wellbeing of Chinese older adults.
Psychometric Properties of the Italian Version of the 25-Item Hikikomori Questionnaire
Authors: Amendola Simone , Presaghi Fabio , Teo Alan R. , Cerutti Rita
Published: October 2022

A serious form of social withdrawal, initially described within Japan as hikikomori, has received increasing attention from the international scientific community during the last decade. The 25-item Hikikomori Questionnaire (HQ-25) was initially developed and validated in Japan. To date, data on its psychometric properties in other populations where cases of hikikomori have been described are still scarce. Thus, the aims of this study were to (1) translate, adapt, and validate the Italian version of the HQ-25 analyzing its psychometric properties; and (2) verify the association between hikikomori and personality functioning, social support, and problematic Internet use. A sample of 372 Italian adults aged 18 to 50 years completed the HQ-25 and measures of psychoticism, personality dysfunction, social support, and problematic Internet use were employed to test the convergent validity of the HQ-25. The data showed a satisfactory fit for a three-factor model, significantly better than a one-factor model. The three factors (socialization, isolation, and emotional support, as in the original study on the HQ-25) correlated positively with psychoticism, personality dysfunction, and problematic Internet use, and correlated negatively with social support. A lifetime history of hikikomori was present in 1.1% of the sample (n = 4). This is the first study to use the Italian validated version of the HQ-25 with an adult population. The findings from this study provide evidence of the satisfactory psychometric properties of the Italian version of the HQ-25 and support further investigation of the HQ-25 as an instrument to help screen for and investigate the presence of hikikomori.
Forecasting Weekly Dengue Cases by Integrating Google Earth Engine-Based Risk Predictor Generation and Google Colab-Based Deep Learning Modeling in Fortaleza and the Federal District, Brazil
Authors: Li Zhichao
Published: October 2022

Efficient and accurate dengue risk prediction is an important basis for dengue prevention and control, which faces challenges, such as downloading and processing multi-source data to generate risk predictors and consuming significant time and computational resources to train and validate models locally. In this context, this study proposed a framework for dengue risk prediction by integrating big geospatial data cloud computing based on Google Earth Engine (GEE) platform and artificial intelligence modeling on the Google Colab platform. It enables defining the epidemiological calendar, delineating the predominant area of dengue transmission in cities, generating the data of risk predictors, and defining multi-date ahead prediction scenarios. We implemented the experiments based on weekly dengue cases during 2013–2020 in the Federal District and Fortaleza, Brazil to evaluate the performance of the proposed framework. Four predictors were considered, including total rainfall (Rsum), mean temperature (Tmean), mean relative humidity (RHmean), and mean normalized difference vegetation index (NDVImean). Three models (i.e., random forest (RF), long-short term memory (LSTM), and LSTM with attention mechanism (LSTM-ATT)), and two modeling scenarios (i.e., modeling with or without dengue cases) were set to implement 1- to 4-week ahead predictions. A total of 24 models were built, and the results showed in general that LSTM and LSTM-ATT models outperformed RF models; modeling could benefit from using historical dengue cases as one of the predictors, and it makes the predicted curve fluctuation more stable compared with that only using climate and environmental factors; attention mechanism could further improve the performance of LSTM models. This study provides implications for future dengue risk prediction in terms of the effectiveness of GEE-based big geospatial data processing for risk predictor generation and Google Colab-based risk modeling and presents the benefits of using historical dengue data as one of the input features and the attention mechanism for LSTM modeling.
Positive Psychology Approaches to Interventions for Cancer Dyads: A Scoping Review
Authors: Otto Amy K. , Ketcher Dana , Reblin Maija , Terrill Alexandra L.
Published: October 2022

Objective: Positive psychology approaches (PPAs) to interventions focus on developing positive cognitions, emotions, and behavior. Benefits of these interventions may be compounded when delivered to interdependent dyads. However, dyadic interventions involving PPAs are relatively new in the cancer context. This scoping review aimed to provide an overview of the available research evidence for use of dyadic PPA-based interventions in cancer and identify gaps in this literature. Methods: Following PRISMA guidelines, we conducted a scoping review of intervention studies that included PPAs delivered to both members of an adult dyad including a cancer patient and support person (e.g., family caregiver, intimate partner). Results: Forty-eight studies, including 39 primary analyses and 28 unique interventions, were included. Most often (53.8%), the support person in the dyad was broadly defined as a “caregiver”; the most frequent specifically-defined role was spouse (41.0%). PPAs (e.g., meaning making) were often paired with other intervention components (e.g., education). Outcomes were mostly individual well-being or dyadic coping/adjustment. Conclusions: Wide variability exists in PPA type/function and their targeted outcomes. More work is needed to refine the definition/terminology and understand specific mechanisms of positive psychology approaches.
Measurement of China’s Green Total Factor Productivity Introducing Human Capital Composition
Authors: Cheng Can , Yu Xiuwen , Hu Heng , Su Zitian , Zhang Shangfeng
Published: October 2022

In the face of resource and environmental problems caused by extensive economic development, China has put forward a green development strategy. Scientific measurement and analysis of green total factor productivity (GTFP) is of great significance for achieving high-quality economic development. By introducing the human capital composition, including education, health, scientific research, and training, this paper study adopts the Slack Based Measure-Global Malmquist-Luenberger (SBM-GML) index to re-measure the GTFP and its decomposition of 30 provinces, municipalities, and autonomous regions in China from 2000 to 2019. The results show that: (1) China’s GTFP has a fluctuating growth trend, with an average annual growth rate of 2.31%. (2) In terms of its decomposition, technical progress is the main force driving GTFP growth, with a contribution rate of 1.59%; the improvement of technical efficiency is a secondary driving force, with a contribution rate of 0.71%. (3) The measurement results of GTFP, considering the human capital composition, are generally higher than those without consideration, and the GTFP growth under the two modes shows a trend of “high in the east and low in the west”. The conclusions have enlightening significance for improving GTFP and the growth potential of the economy in China.
Mental Health and Substance Use of Farmers in Canada during COVID-19
Authors: Thompson Rochelle , Hagen Briana N. M. , Lumley Margaret N. , Winder Charlotte B. , Gohar Basem , Jones-Bitton Andria
Published: October 2022

Farmers in Canada faced higher levels of mental distress than the general public prior to the Coronavirus Disease 2019 (COVID-19) pandemic and are generally less likely than the public to seek help. However, the mental health impacts of COVID-19 on farmers in Canada remain unexplored. Our objective was to investigate mental health outcomes among farmers in Canada by gender and within the context of COVID-19. We conducted a national, online, cross-sectional survey of farmers in Canada (February–May 2021). The survey included validated scales of anxiety, depression, perceived stress, burnout (emotional exhaustion, cynicism, professional efficacy), alcohol use, resilience, and questions regarding participants’ perceived changes in these outcomes during the pandemic. Data were also collected on the impact of COVID-19 specific social and economic factors on mental health, help-seeking, and sense of community belonging through the pandemic. Descriptive statistics were summarized, and Chi-square analyses and t-tests were conducted to compare survey results between genders and to data collected in our similar 2016 survey and normative population data. A total of 1167 farmers participated in the survey. Participants scored more severely across scales than scale norms and the general Canadian population during COVID-19. Scale means were consistent between the 2016 and 2021 samples. Most participants with moderate to severe scores for any outcome reported worsening symptoms since the pandemic began. Women fared significantly worse than men across measures. Over twice as many women reported seeking mental health or substance use support during the pandemic than men. Participants rated the mental health impacts of all social and economic factors related to COVID-19 examined significantly (p < 0.05) differently than the Canadian public. The pandemic has negatively impacted the mental health of farmers in Canada and in ways that differ from the general population. National level and gender-specific mental health supports are needed to help improve the mental health of farmers in Canada.
Quality-of-Life Assessment of Women Undergoing In Vitro Fertilization in Kazakhstan
Authors: Suleimenova Meruyert , Lokshin Vyacheslav , Glushkova Natalya , Karibayeva Sholpan , Terzic Milan
Published: October 2022

Infertility is a problem that affects millions of couples worldwide and has a significant impact on their quality of life. The recently introduced “Fertility Quality of Life Questionnaire (FertiQoL)” quickly became a gold standard for evaluation of the quality of life of patients suffering from infertility. The aim of this study was to determine the quality of life of Kazakhstani women coping with infertility problems by FertiQoL and assess the validity of the questionnaire. This cross-sectional study involved women of reproductive age undergoing an in vitro fertilization (IVF) cycle at a large IVF center in Kazakhstan in the period from 1 September 2020 to 31 September 2021. A total of 453 women out of 500 agreed to participate in the study, and the response rate was 90.6%. The overall Core FertiQoL was 56.95 ± 14.05, and the Treatment FertiQoL was 66.18 ± 11.13 points. Respondents with secondary infertility had statistically significantly higher Emotional (p < 0.001), Mind–body (p = 0.03), Social (p < 0.001), Environment (p = 0.02), and Treatment (p < 0.001) domains of FertiQoL than women with primary infertility. Respondents with a low income had the lowest levels of Total FertiQoL (56.72 ± 11.65). The longer duration of infertility of women undergoing IVF treatment presented the worse scale of Treatment and Total FertiQoL. Cronbach’s alpha revealed good internal reliability for all FertiQoL subscales on the Kazakhstan women’s questionnaire and averaged 0.8, which is an indicator of a high degree of reliability. The Total FertiQoL of Kazakhstan women undergoing IVF treatment was 59.6 ± 11.5, which is considerably lower than European countries. We identified statistically significant differences across medical and demographic groups. As this questionnaire had validity in Kazakhstan survey it possibly be used for both medical counseling and future investigation in our country.
Cone Beam Computed Tomography in the Assessment of the Effectiveness of Physical Therapy with the Use of the Electromagnetic Field Combined with Light Radiation Emitted by LEDs in the Treatment of Inflammation of the Paranasal Sinuses—A Case Study
Authors: Kijak Konrad , Cieślar Grzegorz , Kowacka Małgorzata , Skomro Piotr , Gronwald Helena , Garstka Adam , Lietz-Kijak Danuta
Published: October 2022

Modern high-resolution volumetric tomography, commonly known as cone beam computed tomography (CBCT), is one of the most innovative imaging techniques which can provide views of anatomical structures not attainable by conventional techniques. Magnetic field LED therapy is a physical therapy method, combining the effects of the Extremely Low Frequency-Electromagnetic Field (ELF-EMF) and high-power light radiation emitted by Light Emitting Diodes (LEDs). The method has been widely applied in the treatment and rehabilitation of complications of many medical conditions, including in dentistry. The aim of this study was to use CBCT to assess the effectiveness of the simultaneous use of electromagnetic field and LED light in the physical therapy of paranasal sinusitis. Treatments employing the electromagnetic field combined with LED light were administered to a 39-year-old female outpatient of the physiotherapy ward for rehabilitation therapy of paranasal sinusitis. Normal sinus pneumatization was restored almost completely. Reduction in the swelling of the sinus mucosa was so significant that even the pneumatization of the ethmoid bulla was restored. Physical therapy with the simultaneous use of ELF-EMF and LED light was found to be effective in the rehabilitation of the patient with paranasal sinusitis. Positive effects of the treatment were confirmed by CBCT findings.
Desires and Attitudes towards Telepharmacy Medicine Delivery
Authors: Wattana Konkanok , Yongpraderm Siranee , Sottiyotin Tida , Adulyarat Najmee , Suntonchainugul Cheewarat , Chinakarapong Natcha , Suwanchatre Thanutcha
Published: October 2022

The COVID-19 pandemic has limited healthcare services for patients with non-communicable diseases (NCDs). Hospital pharmacy departments in Thailand apply a new normal pharmacy service known as “telepharmacy” to serve remote pharmacy practice and deliver medication to patients. Current knowledge clearly shows the benefit of each medicine delivery method, but the study of patient’s desires and attitudes towards all drug delivery methods is still limited. To fill the gap, this study aims to investigate desires and attitudes about drug delivery methods among Thai patients living with NCDs who need regular and continuous care. The sample was included by accidentally randomized technique at NCD clinics of the southern Thailand tertiary care hospital. Data were collected between January and March 2021 by a questionnaire that contained three sections: the currently received medicine delivery method, the desires and attitudes about the medicine delivery system, and patients’ demographic information. The majority of patients were women aged 60 years who earned less than 10,000 THB (263.85 USD), were enrolled in the Civil Servant Medical Benefit Scheme (CSMBS), lived 0–15 km from the hospital, living with hypertension, had 1–4 prescribed medications, visited the doctor every 3 months, and received the conventional drug delivery method. The result showed that only the subdistrict health promotion hospital (SHPH) medicine delivery method was at a high level of desire, while the rest including conventional, drug store, postal pharmacy, and drive-thru medicine delivery methods were at medium. Attitudes toward the quality of medicine delivery methods consisted of five dimensions: confidence, timeliness, reliability, empathy, and facilities. Thai NCD patients had positive attitudes toward SHPH and drug store medicine delivery methods that could be seen from the high level of attitude score across all dimensions, while postal pharmacy and drive-thru delivery methods received medium-level attitude scores across all five dimensions.
Methylation in the CHH Context Allows to Predict Recombination in Rice
Authors: Peñuela Mauricio , Gallo-Franco Jenny Johana , Finke Jorge , Rocha Camilo , Gkanogiannis Anestis , Ghneim-Herrera Thaura , Lorieux Mathias
Published: October 2022

DNA methylation is the most studied epigenetic trait. It is considered a key factor in regulating plant development and physiology, and has been associated with the regulation of several genomic features, including transposon silencing, regulation of gene expression, and recombination rates. Nonetheless, understanding the relation between DNA methylation and recombination rates remains a challenge. This work explores the association between recombination rates and DNA methylation for two commercial rice varieties. The results show negative correlations between recombination rates and methylated cytosine counts for all contexts tested at the same time, and for CG and CHG contexts independently. In contrast, a positive correlation between recombination rates and methylated cytosine count is reported in CHH contexts. Similar behavior is observed when considering only methylated cytosines within genes, transposons, and retrotransposons. Moreover, it is shown that the centromere region strongly affects the relationship between recombination rates and methylation. Finally, machine learning regression models are applied to predict recombination using the count of methylated cytosines in the CHH context as the entrance feature. These findings shed light on the understanding of the recombination landscape of rice and represent a reference framework for future studies in rice breeding, genetics, and epigenetics.
Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits
Authors: Smiljanic Sandra , Messaraa Cyril , Lafon-Kolb Virginie , Hrapovic Nina , Amini Nahid , Osterlund Christina , Visdal-Johnsen Lene
Published: October 2022

The Scandinavian region is home to a unique biome with endemic plant species. The aim of this study was to explore this natural diversity and identify plant extracts providing positive skin barrier effects. Six plant extracts were identified as starting material. Following biochemical screening, two candidates outperformed the rest: Betula alba (BA) and Empetrum nigrum (EN). Quantitative PCR analysis showed that BA and EN upregulated barrier genes, when used individually and in combination. Betula alba increased AQP3 and OCLN protein expression, something niacinamide was incapable of. Additionally, the skin barrier was strengthened, evidenced by inhibition of KLK5 and hyaluronidase and showed strong antioxidant and anti-inflammatory activity through DPPH and COX2 inhibition, respectively. A first split-face clinical study was conducted using the combination of extracts versus placebo. There was a significantly better skin restructuring effect and corneocyte cohesion on the side treated with combined extracts. A second split-face clinical study assessed the combined extracts versus 3% niacinamide. Significant variations in skin hydration and TEWL were observed in favor of the extract treated side. In conclusion, we identified a natural alternative to niacinamide for improving skin barrier health, in Scandinavian plant extracts, which yield strong performance, but at a lower concentration.
The Role of the Notch Signaling Pathway in Recovery of Cardiac Function after Myocardial Infarction
Authors: Kachanova Olga , Lobov Arseniy , Malashicheva Anna
Published: October 2022

Myocardial infarction (MI) is a pathological process, evidencing as massive death of cardiomyocytes associated with hypoxic and oxidative stress. The formation of areas of fibrosis ultimately leads to heart failure. There are some mechanisms that contribute to the functional repair of the heart. In most mammals, including humans, the Notch signaling pathway has cardioprotective effects. It is involved in the formation of the heart in embryogenesis and in the restoration of cardiac function after MI due to: (1) reducing oxidative stress; (2) prevention of apoptosis; (3) regulation of inflammation; (4) containment of fibrosis and hypertrophy of cardiomyocytes; (5) tissue revascularization; and (6) regulation of proliferation and differentiation of cardiomyocytes. In addition, the Notch signaling pathway interacts with other signaling cascades involved in the pathogenesis of MI and subsequent cardiac repair. In this review, we consider the Notch signaling pathway as a potential target for therapeutic approaches aimed at improving cardiac recovery after MI.
Update on Innate Immunity in Acute Kidney Injury—Lessons Taken from COVID-19
Authors: Musiał Kinga
Published: October 2022

The serious clinical course of SARS-CoV-2 infection is usually accompanied by acute kidney injury (AKI), worsening prognosis and increasing mortality. AKI in COVID-19 is above all a consequence of systemic dysregulations leading to inflammation, thrombosis, vascular endothelial damage and necrosis. All these processes rely on the interactions between innate immunity elements, including circulating blood cells, resident renal cells, their cytokine products, complement systems, coagulation cascades and contact systems. Numerous simultaneous pathways of innate immunity should secure an effective host defense. Since they all form a network of cross-linked auto-amplification loops, uncontrolled activation is possible. When the actions of selected pathways amplify, cascade activation evades control and the propagation of inflammation and necrosis worsens, accompanied by complement overactivity and immunothrombosis. The systemic activation of innate immunity reaches the kidney, where the damage affecting single tubular cells spreads through tissue collateral damage and triggers AKI. This review is an attempt to synthetize the connections between innate immunity components engaged in COVID-19-related AKI and to summarize the knowledge on the pathophysiological background of processes responsible for renal damage.