bluuebunny/crossref_metadata_2025 huggingface dataset:
Pre-Weaned Calf Rearing on Northern Irish Dairy Farms: Part 1. A Description of Calf Management and Housing Design
Authors: Brown Aaron J , Scoley Gillian , O’Connell Niamh , Robertson Jamie , Browne Amanda , Morrison Steven
Published: June 2021

The first few months of life are of great importance to the longevity and lifetime performance of dairy cows. The nutrition, environment and healthcare management of heifer calves must be sufficient to minimise exposure to stress and disease and enable them to perform to their genetic potential. Lack of reporting of farm management practices in Northern Ireland (NI) makes it difficult to understand where issues impacting health, welfare and performance may occur in the rearing process. The objective of this study was to investigate housing design and management practices of calves on 66 dairy farms across NI over a 3-month period and also identify areas that may cause high risk of poor health and performance in dairy calves. An initial survey was used to detail housing and management practices, with two subsequent visits to each farm used to collect animal and housing-based measurements linked to hygiene management, animal health and performance. Large variations in key elements such as weaning criteria and method, calf grouping method used, nutritional feed plane, and routine hygiene management were identified. The specification of housing, in particular ventilation and stocking density, was highlighted as a potential limiting factor for calf health and performance. Lack of measurement of nutritional inputs, hygiene management practices and calf performance was observed. This poses a risk to farmers’ ability to ensure the effectiveness of key management strategies and recognise poor calf performance and health.
Causes of Abortions in South American Camelids in Switzerland—Cases and Questionnaire
Authors: Rüfli Isabelle , Gurtner Corinne , Basso Walter U. , Vidondo Beatriz , Hirsbrunner Gaby , Zanolari Patrik
Published: June 2021

Over the last decade, South American camelids (SAC) have gained increasing popularity in Switzerland. They are used for several purposes such as fiber and meat production, as companion or guard animals and for trekking activities. The purpose of this study was to investigate the frequency and reasons for pregnancy loss and perinatal death in SAC herds. Within the scope of this study, early embryonic losses could not be identified, as pregnancy examinations by ultrasonography are not performed routinely. Aborted and stillborn fetuses were collected, necropsied and analyzed for infectious abortifacients. A nationwide survey among breeders was carried out. During a 1.5-year period, only eight cases of aborted or stillborn alpaca and llama (out of a population of 6550 animals) were reported by the breeders, and their causes were subsequently analyzed. In half of the cases, Coxiella burnetii was identified in the fetoplacental material. Abortions and stillbirths were reported to be rare in Swiss herds. As a conclusion, recording of embryonic losses through ultrasound training of veterinarians should be impaired and breeders motivated to have abortions and perinatal mortality examined. Special focus should be laid on C. burnetii due to its zoonotic risk.
Molecular and Cellular Responses of DNA Methylation and Thioredoxin System to Heat Stress in Meat-Type Chickens
Authors: Habashy Walid S. , Milfort Marie C. , Rekaya Romdhane , Aggrey Samuel E.
Published: June 2021

Heat stress (HS) causes molecular dysfunction that adversely affects chicken performance and increases mortality. The responses of chickens to HS are extremely complex. Thus, the aim of this study was to evaluate the influence of acute and chronic exposure to HS on the expression of thioredoxin–peroxiredoxin system genes and DNA methylation in chickens. Chickens at 14 d of age were divided into two groups and reared under either constant normal temperature (25 °C) or high temperature (35 °C) in individual cages for 12 days. Five birds per group at one and 12 days post-HS were euthanized and livers were sampled for gene expression. The liver and Pectoralis major muscle were sampled for cellular analysis. mRNA expression of thioredoxin and peroxiredoxins (Prdx) 1, 3, and 4 in the liver were down-regulated at 12 days post-HS compared to controls. The liver activity of thioredoxin reductase (TXNRD) and levels of peroxiredoxin1 (Prdx1) at 12 days post-HS were significantly decreased. The results reveal that there was a significant decrease in DNA methylation at 12 days post HS in liver tissues. In conclusion, pathway of thioredoxin system under HS may provide clues to nutritional strategies to mitigate the effect of HS in meat-type chicken.
Effects of Dietary Saccharomyces cerevisiae YFI-SC2 on the Growth Performance, Intestinal Morphology, Immune Parameters, Intestinal Microbiota, and Disease Resistance of Crayfish (Procambarus clarkia)
Authors: Xu Yan , Li Yiqun , Xue Mingyang , Yang Tao , Luo Xiaowen , Fan Yuding , Meng Yan , Liu Wenzhi , Lin Ge , Li Bo , Zeng Lingbing , Zhou Yong
Published: June 2021

The present study aimed to evaluate the effect of the dietary supplementation of Saccharomyces cerevisiae YFI-SC2 on the growth performance, intestinal morphology, immune parameters, intestinal microbiota, and disease resistance of crayfish (Procambarus clarkia). Crayfish were randomly assigned to six different boxes and two different groups in triplicate. The control group received a basal diet and the treatment group received a diet containing S. cerevisiae at 107 CFU/g. After feeding for 28 days, crayfish of the treatment group exhibited a significantly better weight gain ratio (WGR) and a specific growth rate (SGR) (p < 0.05) than crayfish of the control group. Compared to the treatment group, the control group intestines showed an oedema connective tissue layer and a weak muscle layer. For immune-related genes, Crustin2 expression was similar between the groups, whereas Lysozyme and prophenoloxidase from treatment group expression levels were upregulated significantly (p < 0.05) after 14 and 28 days of feeding. Prophenoloxidase showed the highest expression, with 10.5- and 8.2-fold higher expression than in the control group at 14 and 28 days, respectively. The intestinal microbiota community structure was markedly different between the two groups. After 14 and 28 days of feeding, the relative abundance of Cetobacterium and Lactobacillus increased, whereas Citrobacter and Bacteroides decreased in the treatment group compared with that of the control group. The challenge test showed that crayfish of the treatment group had a significantly enhanced resistance against Citrobacter freundii (p < 0.05). Our results suggest that a S. cerevisiae-containing diet positively influenced the health status, immune parameters, intestinal microbiota composition, and disease resistance of crayfish.
Comparison of the Effect of High-Intensity Laser Therapy (HILT) on Skin Surface Temperature and Vein Diameter in Pigmented and Non-Pigmented Skin in Healthy Racehorses
Authors: Zielińska Paulina , Soroko Maria , Howell Kevin , Godlewska Maria , Hildebrand Weronika , Dudek Krzysztof
Published: June 2021

The aim of the study was to assess differences in the influence of high-intensity laser therapy (HILT) on the skin surface temperature and vein diameter of the lateral fetlock joint region in a group of racehorses with pigmented and non-pigmented skin in the treatment area. Twenty Thoroughbreds were divided into two equal groups: pigmented and non-pigmented skin groups. Each horse received the same HILT treatment. Just before and immediately after HILT, thermographic examination was performed to measure the skin surface temperature and ultrasonographic examination assessed the lateral digital palmar vein diameter. After HILT, the pigmented skin surface temperature increased, while the non-pigmented skin surface temperature decreased, and the difference between both groups was significant (p < 0.001). The vein diameter increased after HILT in horses with pigmented and non-pigmented skin, but the difference between both groups was not significant (p = 0.14). In conclusion, melanin content in the epidermis plays an important role in light energy absorption and photothermal effects. The vein diameter changes after HILT application indicated that the increase in vessel diameter may partly depend on photothermal mechanisms occurring in irradiated tissue. Further research is necessary to describe the physiological and clinical effects of HILT performed on pigmented and non-pigmented skin.
Effects of Hydrolysable Tannin with or without Condensed Tannin on Alfalfa Silage Fermentation Characteristics and In Vitro Ruminal Methane Production, Fermentation Patterns, and Microbiota
Authors: Chen Lei , Bao Xueyan , Guo Gang , Huo Wenjie , Xu Qingfang , Wang Cong , Li Qinghong , Liu Qiang
Published: June 2021

This study was conducted to evaluate the potential of hydrolysable tannin (chestnut tannin, CHT) without or with condensed tannin (quebracho tannin, QT) for modulating alfalfa silage fermentation characteristics and in vitro ruminal methane (CH4) production, fermentation profile, and microbiota. Alfalfa (235 g/kg fresh weight) was ensiled with no tannins (control), 2% CHT (CHT2), 5% CHT (CHT5), the combination of CHT and QT at 1% each (CHQ2), and CHT and QT at 2.5% each (CHQ5) of forage dry matter (DM). The CHQ2 treatment was more effective in reducing DM losses, pH, and ammonia–nitrogen to total nitrogen ratios of alfalfa silage than CHT2 and CHT5 treatments. All tannin treatments decreased ruminal CH4 production, and the magnitude of the decrease was greater for the combinations than the individual ones. Total volatile fatty acid (VFA) concentrations and DM degradation decreased by tannin treatments, but microbial protein (MCP) synthesis increased. The total VFA concentrations and DM degradation were lower with CHQ2 treatment than with CHT5 and CHQ5 treatments, but the MCP concentrations were comparable among these treatments. Tannin inclusion decreased the abundance of the anaerobic fungi Ruminococcus albus and Ruminococcus flavefaciens, but enhanced Fibrobacter succinogenes. The combination of CHT and QT alleviated the inhibition of CHT supply alone in Butyrivibrio fibrisolvens, Ruminobacer amylophilus, and Prevotella ruminicola as well as protease. The results revealed that a combination of HT from CHT and CT from QT at a low level can reduce proteolysis and CH4 production of alfalfa silage without impairing ruminal fermentation and microbiota.
Neurophysiological Mechanisms of Cow–Calf Bonding in Buffalo and Other Farm Animals
Authors: Orihuela Agustín , Mota-Rojas Daniel , Strappini Ana , Serrapica Francesco , Braghieri Ada , Mora-Medina Patricia , Napolitano Fabio
Published: June 2021

In buffaloes and other mammalian farm species, the mother provides food and protection to the young, but she is also the main source of behavioral and social learning for the offspring. It is important that mother and young establish a bond based on a learning mechanism defined as “imprinting” early after parturition during the sensitive period, on which the welfare and survival of the offspring will depend. This review aims to summarize and discuss current knowledge regarding the imprinting process, the neurobiological pathways that are triggered during this sensitive period, and the development of the cow–calf bond. Touch, hearing, vision, and smell seem to be the predominant senses involved during imprinting in buffaloes and other mammalian farm species. In buffalo, bonding is very particular due to the expression of specific behaviors, such as allo-suckling and communal rearing. In general, imprinting and the subsequent bond may be affected by the lack of experience of the mothers or dystocic parturitions, which occur most frequently with male calves and in primiparous dams. The main problems in the development of this process include lack of seeking a protected and isolated place to give birth; moving from the birth-site after parturition; insufficient postpartum care; aversion or aggressiveness towards the newborn, or abandonment of the newborn. The process can develop differently according to the species. However, the correct development of the cow–calf relationship represents, regardless of the species, a key factor for their fitness.
Changing Veterinary Attitudes towards Delivering Biosecurity Advice to Beef Farmers
Authors: Howarth Barnaby Edmund , van Winden Steven
Published: June 2021

Biosecurity advice is an important way veterinarians can help farmers to reduce disease burdens on their farms. Many different factors are at play when delivering this advice, one being veterinary competence and their communication skills. This study looked at the private veterinary practitioners’ perceptions of their own competence to deliver biosecurity advice as part of a longitudinal biosecurity project. Their responses were collected in the form of a telephone questionnaire. The results showed significant increases in private veterinary practitioners’ responses to comfort (p = 0.022), capability (p = 0.002), and consistency (p = 0.006) as well as an increase of uptake of advice (p = 0.015) as the project progressed. The mean time spent delivering biosecurity advice increased and dropped subsequently, suggesting an initially more thorough and later on a more efficient process. The overall perceptions of the veterinarians of the study were also assessed. The results suggest development of the participating veterinarians following the conscious-competence learning model showing a need to improve the knowledge and training of future generations of private veterinary practitioners in the area of biosecurity with, in particular, an increased focus on the importance of the veterinarian–farmer relationship.
The Effect of Humic Mineral Substances from Oxyhumolite on the Coagulation Properties and Mineral Content of the Milk of Holstein-Friesian Cows
Authors: Teter Anna , Kędzierska-Matysek Monika , Barłowska Joanna , Król Jolanta , Brodziak Aneta , Florek Mariusz
Published: June 2021

The study was conducted to determine the effect of humic mineral substances from oxyhumolite added to the diet of Holstein-Friesian cows on the coagulation properties, proximate chemical composition, and mineral profile of milk. The experiment was conducted on 64 cows divided into two groups of 32 each, control (CON) and experimental (H). The group H cows received the humic mineral substances as feed additive, containing 65% humic acids, for 60 days (100 g cow/day). Milk samples were collected twice, after 30 and 60 days. After 30 days no significant changes were observed in the chemical composition, somatic cell count (SCC), mineral content (except potassium), or curd texture parameters. However, the coagulation properties improved. The milk from group H after both 30 and 60 days coagulated significantly (15%) faster on average (p < 0.05), and the curd was about 36% and 28% firmer after 30 and 60 days, respectively (p < 0.05). After 60 days there was an increase in the content of fat (by 0.27 p.p.; p = 0.041), protein (by 0.14 p.p.; p = 0.012), and casein (by 0.12 p.p.; p = 0.029). SCC decreased by 20% (p = 0.023). The curds were significantly harder and less fracturable compared to the control. Calcium and iron content increased as well. The results indicate that humic mineral substances from oxyhumolite in the diet of cows can improve the suitability of milk for cheese production.
Impact of Cardiovascular Failure in Intensive Care Unit-Acquired Pneumonia: A Single-Center, Prospective Study
Authors: Martin-Loeches Ignacio , Ceccato Adrian , Carbonara Marco , li Bassi Gianluigi , di Natale Pierluigi , Nogas Stefano , Ranzani Otavio , Speziale Carla , Senussi Tarek , Idone Francesco , Motos Anna , Ferrer Miquel , Torres Antoni
Published: June 2021

Background: Cardiovascular failure (CVF) may complicate intensive care unit-acquired pneumonia (ICUAP) and radically alters the empirical treatment of this condition. The aim of this study was to determine the impact of CVF on outcome in patients with ICUAP. Methods: A prospective, single-center, observational study was conducted in six medical and surgical ICUs at a University Hospital. CVS was defined as a score of 3 or more on the cardiovascular component of the Sequential Organ Failure Assessment (SOFA) score. At the onset of ICUAP, CVF was reported as absent, transient (if lasting ≤ 3 days) or persistent (>3 days). The primary outcome was 90-day mortality modelled through a Cox regression analysis. Secondary outcomes were 28-day mortality, hospital mortality, ICU length of stay (LOS) and hospital LOS. Results: 358 patients were enrolled: 203 (57%) without CVF, 82 (23%) with transient CVF, and 73 (20%) with persistent CVF. Patients with transient and persistent CVF were more severely ill and presented higher inflammatory response than those without CVF. Despite having similar severity and aetiology, the persistent CVF group more frequently received inadequate initial antibiotic treatment and presented more treatment failures than the transient CVF group. In the persistent CVF group, at day 3, a bacterial superinfection was more frequently detected. The 90-day mortality was significantly higher in the persistent CVF group (62%). The 28-day mortality rates for patients without CVF, with transient and with persistent CVF were 19, 35 and 41% respectively and ICU mortality was 60, 38 and 19% respectively. In the multivariate analysis chronic pulmonary conditions, lack of Pa02/FiO2 improvement at day 3, pulmonary superinfection at day 3 and persistent CVF were independently associated with 90-day mortality in ICUAP patients. Conclusions: Persistent CVF has a significant impact on the outcome of patients with ICUAP. Patients at risk from persistent CVF should be promptly recognized to optimize treatment and outcomes.
Correction: Genovese et al. In Vitro Antibacterial, Anti-Adhesive and Anti-Biofilm Activities of Krameria lappacea (Dombey) Burdet & B.B. Simpson Root Extract against Methicillin-Resistant Staphylococcus aureus Strains. Antibiotics 2021, 10, 428
Authors: Genovese Carlo , D’Angeli Floriana , Bellia Francesco , Distefano Alfio , Spampinato Mariarita , Attanasio Francesco , Nicolosi Daria , Di Salvatore Valentina , Tempera Gianna , Lo Furno Debora , Mannino Giuliana , Milardo Fabio , Li Volti Giovanni
Published: June 2021

The authors would like to make the following corrections to the published paper [...]
Withaferin a Triggers Apoptosis and DNA Damage in Bladder Cancer J82 Cells through Oxidative Stress
Authors: Chien Tsu-Ming , Wu Kuang-Han , Chuang Ya-Ting , Yeh Yun-Chiao , Wang Hui-Ru , Yeh Bi-Wen , Yen Chia-Hung , Yu Tzu-Jung , Wu Wen-Jeng , Chang Hsueh-Wei
Published: June 2021

Withaferin A (WFA), the Indian ginseng bioactive compound, exhibits an antiproliferation effect on several kinds of cancer, but it was rarely reported in bladder cancer cells. This study aims to assess the anticancer effect and mechanism of WFA in bladder cancer cells. WFA shows antiproliferation to bladder cancer J82 cells based on the finding of the MTS assay. WFA disturbs cell cycle progression associated with subG1 accumulation in J82 cells. Furthermore, WFA triggers apoptosis as determined by flow cytometry assays using annexin V/7-aminoactinomycin D and pancaspase detection. Western blotting also supports WFA-induced apoptosis by increasing cleavage of caspases 3, 8, and 9 and poly ADP-ribose polymerase. Mechanistically, WFA triggers oxidative stress-association changes, such as the generation of reactive oxygen species and mitochondrial superoxide and diminishment of the mitochondrial membrane potential, in J82 cells. In response to oxidative stresses, mRNA for antioxidant signaling, such as nuclear factor erythroid 2-like 2 (NFE2L2), catalase (CAT), superoxide dismutase 1 (SOD1), thioredoxin (TXN), glutathione-disulfide reductase (GSR), quinone dehydrogenase 1 (NQO1), and heme oxygenase 1 (HMOX1), are overexpressed in J82 cells. In addition, WFA causes DNA strand breaks and oxidative DNA damages. Moreover, the ROS scavenger N-acetylcysteine reverts all tested WFA-modulating effects. In conclusion, WFA possesses anti-bladder cancer effects by inducing antiproliferation, apoptosis, and DNA damage in an oxidative stress-dependent manner.
An Acoustic Way to Support Japanese Children’s Effective English Learning in School Classrooms
Authors: Evans Naoko , Kaneko Miki , Seleznov Ivan , Shigematsu Taiki , Kiyono Ken
Published: June 2021

In this paper, the importance of implementing good acoustic conditions in classrooms using sound amplification systems is investigated to support more effective English education for elementary school children. To date, the failure of educating English as a second language at Japanese schools has been demonstrated by poor English conversation ability of those who completed a compulsory six-year English language course at Japanese junior-high and high schools (age 12–18). To amend the situation, teaching English became compulsory at grade three (age 8–9) and above at most Japanese elementary schools in the 2020 academic year. We conducted acoustic measurements of two types of sound amplification systems, a pair of PC loudspeakers and another with a loudspeaker array, in a typical classroom at an elementary school in Japan. We also analysed English listening test results of 216 Japanese native children (age 11–12) who were learning English in their usual classes in Japan, to compare the effects of those two systems. Results of logistic regression analysis adjusted by the discrimination difficulty of word pairs demonstrated the statistically significant association between correct answer rate of the English tests and classroom acoustic factors. Although, on average, upgrading the sound amplification system had positive effects on the correct answer rate, it also had a negative impact when the word pairs had English phoneme contrasts that do not appear in Japanese phoneme structure. Combined with the acoustic measurements’ results, it was also revealed that heterogeneous sound fields that depend on seat positions could be compensated using sound amplification systems with loudspeaker arrays. Our findings suggest that improvement of both acoustic quality and teaching methods is required for children to acquire English communication skills effectively in their classroom.
Non-Proportionality Indices and Error Constraint in Modal Analysis of Viscously Damped Linear Structures
Authors: Conde Jorge , Bernabeu Alejandro
Published: June 2021

Use of modal procedures in systems with non-proportional damping (such as structures with added viscous damping systems) results in response errors, shown in this study to depend on dissimilar and often conflicting conditions for different variables and stories; thus, it is not possible to propose simple rules based on structural or damping properties to limit the error in a global way. However, four existing indices (originally proposed to measure damping non-proportionality) present a positive correlation with the extreme errors in modal procedures for all variables and stories. Thus, limiting the index value is a sufficient condition to keep the error in all variables within a given threshold. For practical application, limit values for these indices are tabulated as a function of error and can be used as an acceptance criterion for the validity of modal procedures.
Radon over Kimberlite Pipes: Estimation of the Emanation Properties of Rocks (Lomonosov Diamond Deposit, NW Russia)
Authors: Yakovlev Evgeny , Puchkov Andrey
Published: June 2021

In this paper, using the example of the Lomonosov diamond deposit, experimental studies of rocks were carried out to assess the main radiation and physical factors affecting the formation of the radon field over the kimberlite pipes of the Arkhangelsk diamondiferous province. For various types of rocks, represented by vent kimberlites, tuffaceous-sedimentary rocks of the crater and enclosing and overlying sediments, the following were studied: porosity, density, activity of radium-226, activity of radon in a free state, level of radon production, and emanation coefficient. The research results showed that the greatest amount of radon in a free state is produced by rocks of the near-pipe space, represented by the enclosing Vendian V2 deposits and characterized by high values of the emanation coefficient, radium activity, radon production level and porosity. This fact is associated with the structural and geological features of the near-pipe space, which was exposed to the impact of kimberlite magma on the host rocks. The lowest values of these parameters are characteristic of the kimberlites of the vent facies, which limits the formation of free radon in the body of the pipe. The results of the experimental studies create prospects for the development of emanation methods for searching for kimberlite pipes in the conditions of the Arkhangelsk diamondiferous province.
Enhanced Methane Production from Anaerobic Co-Digestion of Wheat Straw Rice Straw and Sugarcane Bagasse: A Kinetic Analysis
Authors: Meraj Saadia , Liaquat Rabia , Raza Naqvi Salman , Sheikh Zeshan , Zainab Atoofa , Khoja Asif Hussain , Juchelkova Dagmar , Atabani Abdulaziz
Published: June 2021

Future energy and environmental issues are the major driving force towards increased global utilization of biomass, especially in developing countries like Pakistan. Lignocellulosic residues are abundant in Pakistan. The present study investigated the best-mixed proportion of mechanically pretreated lignocellulosic residues i.e., wheat straw and rice straw (WSRS), bagasse and wheat straw (BAWS), bagasse, and rice straw (BARS), bagasse, wheat straw, and rice straw (BAWSRS) through anaerobic co-digestion. Anaerobic batch mode bioreactors comprising of lignocellulosic proportions and control bioreactors were run in parallel at mesophilic temperature (35 °C) for the substrate to inoculum (S/I) ratio of 1.5 and 2.5. Maximum and stable biomethane production was observed at the substrate to inoculum (S/I) ratio of 1.5, and the highest biomethane yield 339.0089123 NmLCH4/gVS was achieved by co-digestion of wheat straw and rice straw (WSRS) and lowest 15.74 NmLCH4/gVS from bagasse and rice straw (BARS) at 2.5 substrates to inoculum ratio. Furthermore, anaerobic reactor performance was determined by using bio-kinetic parameters i.e., production rate (Rm), lag phase (λ), and coefficient of determination (R2). The bio-kinetic parameters were evaluated by using kinetic models; first-order kinetics, Logistic function model, Modified Gompertz Model, and Transference function model. Among all kinetic models, the Logistic function model provided the best fit with experimental data followed by Modified Gompertz Model. The study suggests that a decrease in methane production was due to lower hydrolysis rate and higher lignin content of the co-digested substrates, and mechanical pretreatment leads to the breakage of complex lignocellulosic structure. The organic matter degradation evidence will be utilized by the biogas digesters developed in rural areas of Pakistan, where these agricultural residues are ample waste and need a technological solution to manage and produce renewable energy.
Introduction of the ARDS—Anti-Ransomware Defense System Model—Based on the Systematic Review of Worldwide Ransomware Attacks
Authors: Szücs Veronika , Arányi Gábor , Dávid Ákos
Published: June 2021

We live in a world of digital information communication and digital data storage. Following the development of technology, demands from the user side also pose serious challenges for developers, both in the field of hardware and software development. However, the increasing penetration of the Internet, IoT and digital solutions that have become available in almost every segment of life, carries risks as well as benefits. In this study, the authors present the phenomenon of ransomware attacks that appear on a daily basis, which endangers the operation and security of the digital sphere of both small and large enterprises and individuals. An overview of ransomware attacks, the tendency and characteristics of the attacks, which have caused serious financial loss and other damages to the victims, are presented. This manuscript also provides a brief overview of protection against ransomware attacks and the software and hardware options that enhance general user security and their effectiveness as standalone applications. The authors present the results of the study, which aimed to explore how the available software and hardware devices can implement digital user security. Based on the results of the research, the authors propose a complex system that can be used to increase the efficiency of network protection and OS protection tools already available to improve network security, and to detect ransomware attacks early. As a result, the model of the proposed protection system is presented, and it can be stated that the complex system should be able to detect ransomware attacks from either the Internet or the internal network at an early stage, mitigate malicious processes and maintain data in recoverable state.
Correction: Refaat et al. Multi-Stage Dynamic Transmission Network Expansion Planning Using LSHADE-SPACMA. Appl. Sci. 2021, 11, 2155
Authors: Refaat Mohamed M. , Aleem Shady H. E. Abdel , Atia Yousry , Ali Ziad M. , Sayed Mahmoud M.
Published: June 2021

The authors wish to make the following corrections to this paper [...]
Balance Measurement Using Microsoft Kinect v2: Towards Remote Evaluation of Patient with the Functional Reach Test
Authors: Ayed Ines , Jaume-i-Capó Antoni , Martínez-Bueso Pau , Mir Arnau , Moyà-Alcover Gabriel
Published: June 2021

To prevent falls, it is important to measure periodically the balance ability of an individual using reliable clinical tests. As Red Green Blue Depth (RGBD) devices have been increasingly used for balance rehabilitation at home, they may also be used to assess objectively the balance ability and determine the effectiveness of a therapy. For this, we developed a system based on the Microsoft Kinect v2 for measuring the Functional Reach Test (FRT); one of the most used balance clinical tools to predict falls. Two experiments were conducted to compare the FRT measures computed by our system using the Microsoft Kinect v2 with those obtained by the standard method, i.e., manually. In terms of validity, we found a very strong correlation between the two methods (r = 0.97 and r = 0.99 (p < 0.05), for experiments 1 and 2, respectively). However, we needed to correct the measurements using a linear model to fit the data obtained by the Kinect system. Consequently, a linear regression model has been applied and examining the regression assumptions showed that the model works well for the data. Applying the paired t-test to the data after correction indicated that there is no statistically significant difference between the measurements obtained by both methods. As for the reliability of the test, we obtained good to excellent within repeatability of the FRT measurements tracked by Kinect (ICC = 0.86 and ICC = 0.99, for experiments 1 and 2, respectively). These results suggested that the Microsoft Kinect v2 device is reliable and adequate to calculate the standard FRT.
Recognition of LHD Position and Maneuvers in Underground Mining Excavations—Identification and Parametrization of Turns
Authors: Witulska Justyna , Stefaniak Paweł , Jachnik Bartosz , Skoczylas Artur , Śliwiński Paweł , Dudzik Marek
Published: June 2021

The Inertial Measurement Unit (IMU) is widely used in the monitoring of mining assets. A good example is the Polish underground copper ore mines of KGHM, where research work with the use of the IMU has been carried out for several years. The potential of inertial sensors was ensured by the development of advanced analytics using machine learning methods to support the maintenance management of an extensive machine park and machine manufacturer in adapting various construction elements to mining conditions. The key algorithms developed in the field of inertial data concern: identification of cycles and components of the haulage process operations, identification of dynamic overloads, technical diagnostics of rotating elements, assessment of road conditions (bumps, slopes, damages), assessment of the technical condition of the pavement, assessment of the operator’s driving style, and finally the machine location in the mining excavation. One of the key operational contexts, necessary in the development of analytics for underground mining vehicles, is the identification of the turning moment of the machine at the intersection together with the determination of the driving direction and the turn angle. In the case of a mine with a room-and-pillar system, where the excavation system has the Manhattan structure, it is possible to use many simplifications to correctly estimate the machine motion path. The identification of the spatial context and the turning maneuver is of key importance both in the development of the machine location system, but also in multi-dimensional analyzes, including the analysis of dynamic overloads or the assessment of the operator’s driving style and work safety. The article presents a comparison of several mathematical models used for the machine turn detection problem, which were trained and tested on the real-life industrial data recorded using IMU during a single working shift of the self-propelled machine.
Nano-Porous Silica-Aerogel-Incorporated Composite Materials for Thermal-Energy-Efficient Pitched Roof in the Tropical Region
Authors: Ismail Fouad Ismail , Farhan Syed Ahmad , Shafiq Nasir , Husna Nadzhratul , Sharif Muhammad Taufiq , Affan Syed Uthman , Veerasenan Arul Kamal
Published: June 2021

Silica aerogel possesses an ultra-low thermal conductivity by virtue of its nano-structure. Owing to the fragility of monolithic aerogel, the development and production of aerogel-based insulation materials involve the incorporation of granular aerogel with other materials to form composite materials. In the present study, the application of silica-aerogel-incorporated composite cement paste as render on the roof-top surface is coupled with the installation of a novel silica-aerogel-incorporated composite insulation board below the roof tiles. Control and silica-aerogel-incorporated samples of the composite cement paste and insulation were prepared. Thermal conductivity and strength tests were performed on the samples. A simulation study was performed on a Building Information Model subjected to a tropical climate to project the resultant impact of the cement render coupled with the insulation board on the thermal-energy-efficiency of the roof. For optimization of thermal and strength performances, silica aerogel contents of 4 wt.% and 3 wt.% were selected for the cement render and insulation board, respectively. The projected annual cooling load and energy savings revealed that the application of a 20-mm cement render, coupled with the installation of a 100-mm thick insulation board, is recommended as the optimum roof configuration.
Auto-Regressive Integrated Moving-Average Machine Learning for Damage Identification of Steel Frames
Authors: Gao Yuqing , Mosalam Khalid M. , Chen Yueshi , Wang Wei , Chen Yiyi
Published: June 2021

Auto-regressive (AR) time series (TS) models are useful for structural damage detection in vibration-based structural health monitoring (SHM). However, certain limitations, e.g., non-stationarity and subjective feature selection, have reduced its wide-spread use. With increasing trends in machine learning (ML) technologies, automated structural damage recognition is becoming popular and attracting many researchers. In this paper, we combined TS modeling and ML classification to automatically extract damage features and overcome the limitation of non-stationarity. We propose a two-stage framework, namely auto-regressive integrated moving-average machine learning (ARIMA-ML) with modules for pre-processing, model parameter determination, feature extraction, and classification. Based on shaking table tests of a space steel frame, floor acceleration data were collected and labeled according to experimental observations and records. Subsequently, we designed three damage classification tasks for: (1) global damage detection, (2) local damage detection, and (3) local damage pattern recognition. The results from these three tasks indicated the robustness and accuracy of the proposed framework where 97%, 98%, and 80% average segment accuracy were achieved, respectively. The confusion matrix results showed the unbiased model performance even under an imbalanced-class distribution. In summary, the presented study revealed the high potential of the proposed ARIMA-ML framework in vibration-based SHM.
Metal Bioaccumulation by Carp and Catfish Cultured in Lake Chapala, and Weekly Intake Assessment
Authors: Alvarado Claudia , Cortez-Valladolid Diego M. , Herrera-López Enrique J. , Godínez Ximena , Ramírez José Martín
Published: June 2021

Aquaculture offers great potential for fish production in Lake Chapala, but reports of heavy metal contamination in fish have identified a main concern for this activity. In the present study, cultures of the species Cyprinus carpio and Ictalurus punctatus were grown in a net cage in Lake Chapala. The patterns of heavy metal accumulation (Cu, Zn, Cd, Hg, Pb, As) in muscle and liver were monitored in order to evaluate the level of metal incorporation in the fish. Estimates of weekly metal intake (EWI) were made based on the results of the concentrations in edible parts of fish of commercial size. The patterns of metal bioaccumulation between tissues and species showed that liver had a higher concentrating capacity for Zn, Cu, Cd, and Pb. In contrast, similar concentrations of Hg and As were found in the liver and muscle tissue. According to the EWI estimates, the heavy metals in these cultured fish do not represent a risk for human consumption.
Comparison of Countermovement and Preferred-Style Jump Biomechanics in Male Basketball Players
Authors: Kipp Kristof , Krzyszkowski John , Smith Todd , Geiser Christopher , Kim Hoon
Published: June 2021

The purpose of this study was to investigate and compare the biomechanics of countermovement (CMJ) and preferred-style (PrefJ) jumps. Eight male basketball players (age: 19 ± 1 year; height: 1.84 ± 0.14 m; mass: 92.8 ± 11.4 kg) participated in a cross-sectional study for which they performed max effort CMJ and PrefJ while motion capture and force plate data were recorded. The CMJ were performed according to common procedures. For the PrefJ, the eight players chose to use a short approach run and a step-in jump, with a clear lead and trail leg foot contact pattern. Vertical ground reaction forces (GRF), center-of-mass (COM) parameters, as well as hip, knee, and ankle flexion angles, extension velocities, net joint moments, powers, and work were all calculated and used for analysis. Bi-lateral data from the CMJ were averaged, whereas lead and trail leg data from the PrefJ were kept separated. The PrefJ was characterized by greater jump height and GRF and shorter contact times. Joint-level differences indicated that the PrefJ was characterized by larger joint kinetics. Importantly, very few biomechanical variables of the CMJ and PrefJ were correlated, which suggests that each jump type is characterized by unique movement strategies. Since PrefJ may better represent athlete- and sport-specific movement pattern, these findings could have implications for assessing and monitoring neuromuscular performance of basketball players.
A Finite Element Study on Compressive Resistance Degradation of Square and Circular Steel Braces under Axial Cyclic Loading
Authors: Hussain Hubdar , Gao Xiangyu , Shi Anqi
Published: June 2021

In this study, detailed finite element analysis was conducted to examine the seismic performance of square and circular hollow steel braces under axial cyclic loading. Finite element models of braces were constructed using ABAQUS finite element analysis (FEA) software and validated with experimental results from previous papers to expand the specimen’s matrix. The influences of cross-section shape, slenderness ratio, and width/diameter-to-thickness ratio on hysteretic behavior and compressive-tensile strength degradation were studied. Simulation results of parametric studies show that both square and circular hollow braces have a better cyclic performance with smaller slenderness and width/diameter-to-thickness ratios, and their compressive-tensile resistances ratio significantly decreases from cycle to cycle after the occurrence of the global buckling of braces.
Co-Package Technology Platform for Low-Power and Low-Cost Data Centers
Authors: Papatryfonos Konstantinos , Selviah David R. , Maman Avi , Hasharoni Kobi , Brimont Antoine , Zanzi Andrea , Kraft Jochen , Sidorov Victor , Seifried Marc , Baumgartner Yannick , Horst Folkert , Offrein Bert Jan , Lawniczuk Katarzyna , Broeke Ronald G. , Terzenidis Nikos , Mourgias-Alexandris George , Tang Mingchu , Seeds Alwyn J. , Liu Huiyun , Sanchis Pablo , Moralis-Pegios Miltiadis , Manolis Thanasis , Pleros Nikos , Vyrsokinos Konstantinos , Sirbu Bogdan , Eichhammer Yann , Oppermann Hermann , Tekin Tolga
Published: June 2021

We report recent advances in photonic–electronic integration developed in the European research project L3MATRIX. The aim of the project was to demonstrate the basic building blocks of a co-packaged optical system. Two-dimensional silicon photonics arrays with 64 modulators were fabricated. Novel modulation schemes based on slow light modulation were developed to assist in achieving an efficient performance of the module. Integration of DFB laser sources within each cell in the matrix was demonstrated as well using wafer bonding between the InP and SOI wafers. Improved semiconductor quantum dot MBE growth, characterization and gain stack designs were developed. Packaging of these 2D photonic arrays in a chiplet configuration was demonstrated using a vertical integration approach in which the optical interconnect matrix was flip-chip assembled on top of a CMOS mimic chip with 2D vertical fiber coupling. The optical chiplet was further assembled on a substrate to facilitate integration with the multi-chip module of the co-packaged system with a switch surrounded by several such optical chiplets. We summarize the features of the L3MATRIX co-package technology platform and its holistic toolbox of technologies to address the next generation of computing challenges.
Anticipating Future Behavior of an Industrial Press Using LSTM Networks
Authors: Mateus Balduíno César , Mendes Mateus , Farinha José Torres , Cardoso António Marques
Published: June 2021

Predictive maintenance is very important in industrial plants to support decisions aiming to maximize maintenance investments and equipment’s availability. This paper presents predictive models based on long short-term memory neural networks, applied to a dataset of sensor readings. The aim is to forecast future equipment statuses based on data from an industrial paper press. The datasets contain data from a three-year period. Data are pre-processed and the neural networks are optimized to minimize prediction errors. The results show that it is possible to predict future behavior up to one month in advance with reasonable confidence. Based on these results, it is possible to anticipate and optimize maintenance decisions, as well as continue research to improve the reliability of the model.
Does Pressurized Carbon Dioxide Lavage Improve Bone Cleaning in Cemented Arthroplasty?
Authors: Knappe Kevin , Stadler Christian , Innmann Moritz , Schonhoff Mareike , Gotterbarm Tobias , Renkawitz Tobias , Jaeger Sebastian
Published: June 2021

Cemented implant fixation in total joint arthroplasty has been proven to be safe and reliable with good long-term results. However, aseptic loosening is one of the main reasons for revision, potentially caused by poor cementation with low penetration depth in the cancellous bone. Aim of this prospective laboratory study was, to compare impact pressure and cleaning effects of pulsatile saline lavage to novel carbon dioxide lavage in a standardized carbon foam setup, to determine whether or not additional use of carbon dioxide lavage has any impact on cleaning volume or cleaning depth in cancellous bone. Carbon specimens simulating human cancellous bone were filled with industrial grease and then underwent a standardized cleaning procedure. Specimens underwent computed tomography pre- and post-cleaning. Regarding the impact pressure, isolated carbon dioxide lavage showed significant lower pressure compared to pulsatile saline lavage. Even though the combination of carbon dioxide lavage and pulsatile saline lavage had a positive cleaning effect compared to the isolated use of pulsatile saline lavage or carbon dioxide lavage, this was not significant in terms of cleaning volume or cleaning depth.
Dynamic Characteristics of the Bouc–Wen Nonlinear Isolation System
Authors: Zhang Zhiying , Tian Xin , Ge Xin
Published: June 2021

The Bouc–Wen nonlinear hysteretic model has many control parameters, which has been widely used in the field of seismic isolation. The isolation layer is the most important part of the isolation system, which can be effectively simulated by the Bouc–Wen model, and the isolation system can reflect different dynamic characteristics under different control parameters. Therefore, this paper mainly studies and analyzes the nonlinear dynamic characteristics of the isolation system under different influence factors based on the incremental harmonic balance method, which can provide the basis for the dynamic design of the isolation system.
Numerical Investigation of the Effect of Air Leaking into the Working Fluid on the Performance of a Steam Ejector
Authors: Li He , Wang Xiaodong , Ning Jiuxin , Zhang Pengfei , Huang Hailong
Published: June 2021

This paper investigated the effect of air leaking into the working fluid on the performance of a steam ejector. A simulation of the mixing of air into the primary and secondary fluids was performed using CFD. The effects of air with a 0, 0.1, 0.3 and 0.5 mass fraction on the entrainment ratio and internal flow structure of the steam ejector were studied, and the coefficient distortion rates for the entrainment ratios under these air mass fractions were calculated. The results demonstrated that the air modified the physical parameters of the working fluid, which is the main reason for changes in the entrainment ratio and internal flow structure. The calculation of the coefficient distortion rate of the entrainment ratio illustrated that the air in the primary fluid has a more significant impact on the change in the entrainment ratio than that in the secondary fluid under the same air mass fraction. Therefore, the air mass fraction in the working fluid must be minimized to acquire a precise entrainment ratio. Furthermore, this paper provided a method of inspecting air leakage in the experimental steam ejector refrigeration system.
Opportunities for Machine Learning in District Heating
Authors: Mbiydzenyuy Gideon , Nowaczyk Sławomir , Knutsson Håkan , Vanhoudt Dirk , Brage Jens , Calikus Ece
Published: June 2021

The district heating (DH) industry is facing an important transformation towards more efficient networks that utilise significantly lower water temperatures to distribute the heat. This change requires taking advantage of new technologies, and Machine Learning (ML) is a popular direction. In the last decade, we have witnessed an extreme growth in the number of published research papers that focus on applying ML techniques to the DH domain. However, based on our experience in the field, and an extensive review of the state-of-the-art, we perceive a mismatch between the most popular research directions, such as forecasting, and the challenges faced by the DH industry. In this work, we present our findings, explain and demonstrate the key gaps between the two communities and suggest a road-map ahead towards increasing the impact of ML research in the DH industry.