bluuebunny/crossref_metadata_2025 huggingface dataset:
The roles of sodium-potassium-chloride cotransporter isoform-1 in acute lung injury
Authors: Hsieh Po-Chun , Wu Yao-Kuang , Kuo Chan-Yen , Lee Yen-Hsien , Yang Mei-Chen , Lan Chou-Chin
Published: April 2022

Acute lung injury (ALI) is often characterized by severe lung inflammation and pulmonary edema with poor gas exchange and hypoxemia. Alveolar inflammation and water flooding are, in fact, notable features of ALI pathogenesis. The sodium-potassium-chloride co-transporter isoform 1 (NKCC1), localized at the basolateral surface of the lung epithelium, drives water transport via back transport of Na+ and Cl− to the alveolar air space. NKCC1, therefore, is crucial in regulating alveolar fluid. Increased expression of NKCC1 results in increased alveolar fluid secretion and impaired alveolar fluid clearance. During ALI, the with no lysine kinase (WNK), oxidative stress responsive kinase 1 (OSR1), and STE20/SPS1-related proline/alanine-rich kinase (SPAK) pathways are activated, which upregulates NKCC1 expression. Proinflammatory cytokines also enhance the expression of NKCC1 via c-Jun N-terminal kinase-and p38-dependent pathways. NKCC1 activation also increases the expression of proinflammatory cytokines via cell rupture and activation of macrophages. Increased proinflammatory cytokines, in turn, recruit inflammatory cells to the site of injury and cause further lung damage. Animals with high expression of NKCC1 show more severe lung injury with presentations of more severe pulmonary edema and microvascular permeability, higher expression of proinflammatory cytokines, and greater neutrophilic infiltration. In contrast, animals with low expression of NKCC1 or those treated with NKCC1 inhibitors show less severe lung injury with milder levels of presentations of ALI. These reports collectively highlight a novel role of NKCC1 in ALI pathogenesis. Manipulation of NKCC1 expression levels could, therefore, represent novel modalities for effective ALI treatment.
Dynamics of hospitalizations and in-hospital deaths from COVID-19 in northeast Brazil: a retrospective analysis based on the circulation of SARS-CoV-2 variants and vaccination coverage
Authors: Martins-Filho Paulo Ricardo , de Souza Araújo Adriano Antunes , Quintans-Júnior Lucindo José , Soares Bárbara dos Santos , Barboza Waneska de Souza , Cavalcante Taise Ferreira , Santos Victor Santana
Published: April 2022

This study investigated the dynamics of hospitalizations and in-hospital deaths from coronavirus disease 2019 (COVID-19) throughout the pandemic in northeast Brazil, the Brazilian region with the worst socioeconomic indicators. In total, 141,445 cases, 8,213 hospital admissions, and 1,644 in-hospital deaths from COVID-19 were registered from March 14, 2020 to February 5, 2022. The overall rates of hospitalization and in-hospital deaths were 5.8% and 20.0%, respectively. The hospitalization and death rates significantly decreased over time, which may have been related to progress in vaccination. During the spread of the Gamma variant (January to June 2021), most hospitalized individuals were young adults, and approximately 40% of deaths occurred in this age group. During the predominance of Delta (July to December 2021), over 75% of deaths occurred among the elderly and unvaccinated or partially vaccinated individuals. This rate decreased to 42.3% during the transmission of the Omicron variant (January to February 2022), during which 34.6% of deaths were recorded among fully vaccinated individuals (2 doses) and 23.1% among those who received full vaccination and a booster. The Omicron-driven third wave was associated with a rise in the proportion of deaths among vaccinated individuals, especially among those who had not received a booster dose.
The Asenze Cohort Study in KwaZulu-Natal, South Africa: protocol and cohort profile
Authors: Desmond Chris , Norwitz Gabriella A. , Kvalsvig Jane D. , Gruver Rachel S. , Kauchali Shuaib , Watt Kathryn G. , Myeza Nonhlanhla P. , Munsami Adele , Davidson Leslie L.
Published: April 2022

The Asenze cohort is set in South Africa, a middle-income country impacted by one of the highest global rates of people living with HIV/AIDS and high levels of socioeconomic inequality. This longitudinal population-based cohort of children and their primary caregivers assesses household and caregiver functioning, child health, social well-being, and neuro-development from childhood through adolescence. Almost 1,600 children born at the peak of the human immunodeficiency virus epidemic (2003-2005) were followed (with their primary caregivers) in 3 waves, between 2008 and 2021, at average ages of 5, 7, and 16. Wave 3 is currently underway, having assessed over 1,100 of the original wave 1 children. Wave 4 begins in 2022. The study, with a dyadic structure, uses a broad range of measures, validated in South Africa or recommended for global use, that address physical, social and neuro-development in childhood and adolescence, and the social, health, and psychological status of children’s primary caregivers. The Asenze study deepens our understanding of childhood physical, cognitive, and social abilities and/or disabilities, including risk-taking behaviors, and biological, environmental, and social determinants of health. We anticipate the findings will contribute to the development of community-informed interventions to promote well-being in this South African population and elsewhere.
Co-circulation of Chikungunya Virus during the 2015–2017 Zika Virus Outbreak in Pernambuco, Brazil: An Analysis of the Microcephaly Epidemic Research Group Pregnancy Cohort
Authors: Lobkowicz Ludmila , Miranda-Filho Demócrito de Barros , Montarroyos Ulisses Ramos , Martelli Celina Maria Turchi , de Araújo Thalia Velho Barreto , De Souza Wayner Vieira , Bezerra Luciana Caroline Albuquerque , Dhalia Rafael , Marques Ernesto T. A. , Sanchez Clemente Nuria , Webster Jayne , Vaughan Aisling , Webb Emily L. , Brickley Elizabeth B. , Ximenes Ricardo Arraes de Alencar , _ _
Published: April 2022

Co-circulation of arthropod-borne viruses, particularly those with shared mosquito vectors like Zika (ZIKV) and Chikungunya (CHIKV), is increasingly reported. An accurate differential diagnosis between ZIKV and CHIKV is of high clinical importance, especially in the context of pregnancy, but remains challenging due to limitations in the availability of specialized laboratory testing facilities. Using data collected from the prospective pregnancy cohort study of the Microcephaly Epidemic Research Group, which followed up pregnant persons with rash during the peak and decline of the 2015–2017 ZIKV epidemic in Recife, Pernambuco, Brazil, this study aims to describe the geographic and temporal distribution of ZIKV and CHIKV infections and to investigate the extent to which ZIKV and CHIKV infections may be clinically differentiable. Between December 2015 and June 2017, we observed evidence of co-circulation with laboratory confirmation of 213 ZIKV mono-infections, 55 CHIKV mono-infections, and 58 sequential ZIKV/CHIKV infections (i.e., cases with evidence of acute ZIKV infection with concomitant serological evidence of recent CHIKV infection). In logistic regressions with adjustment for maternal age, ZIKV mono-infected cases had lower odds than CHIKV mono-infected cases of presenting with arthralgia (aOR, 99% CI: 0.33, 0.15–0.74), arthritis (0.35, 0.14–0.85), fatigue (0.40, 0.17–0.96), and headache (0.44, 0.19–1.00). However, sequential ZIKV/CHIKV infections complicated discrimination, as they did not significantly differ in clinical presentation from CHIKV mono-infections. These findings suggest clinical symptoms alone may be insufficient for differentiating between ZIKV and CHIKV infections during pregnancy and therefore laboratory diagnostics continue to be a valuable tool for tailoring care in the event of arboviral co-circulation.
Financial Incentives, Not Behavioral Nudges, Led to Optimized HIV Testing among Pregnant Women in a High-Burden Urban Population in Ecuador
Authors: Reina Ortiz Miguel , Grunauer Michelle , Gutierrez Erika , Izurieta Ricardo , Macis Mario , Phan Phillip , Rosas Carlos , Teran Enrique
Published: April 2022

Behavioral economic principles are increasingly being used in the fight against HIV, including improving voluntary testing in sub-Saharan Africa and South America. However, behavioral nudges have not been widely tested as a strategy to optimize HIV testing in pregnant women. Here, we assessed whether behavioral nudges or financial incentives were effective in optimizing HIV testing among pregnant women in a high-HIV burden setting. A randomized clinical trial was conducted between May 21 and Oct 5, 2018, to allocate pregnant women in Ecuador into three study arms: information only, soft commitment (i.e., a behavioral nudge), and financial incentives. All participants received an informational flyer, including the address of a testing location. Participants in the soft-commitment arm signed and kept a form on which they committed to get tested for HIV. Those in the financial incentive arm received a $10 incentive when tested for HIV. A stepwise logistic regression analysis estimated the effect of the study arms on HIV testing rate. Participants in the financial-incentive arm had higher odds of getting an HIV test (adjusted odds ratio 17.06, P < 0.001) as compared with information-only participants. Soft-commitment had the opposite effect (adjusted odds ratio 0.14, P = 0.014). Financial incentives might be useful in improving HIV testing among pregnant women, especially among those who might be at higher risk but who have not completed an HIV test.
Detection of Japanese Encephalitis Virus RNA in Host-Questing Ticks in Japan, 2019–2020
Authors: Kobayashi Daisuke , Kuwata Ryusei , Kimura Toshiya , Faizah Astri Nur , Azerigyik Faustus Akankperiwen , Higa Yukiko , Hayashi Toshihiko , Sawabe Kyoko , Isawa Haruhiko
Published: April 2022

Japanese encephalitis virus (JEV), a mosquito-borne virus, causes severe clinical symptoms in humans in the Asian-Pacific region, where it circulates in a primary transmission cycle among Culex tritaeniorhynchus mosquitoes, domestic swine (Sus scrofa domesticus), and wading birds. We report here an anomalous result that mosquito-borne JEV was detected in unfed host-questing ticks collected from the field in Japan. JEV genomic RNA was detected in four pools of Haemaphysalis flava nymphs collected in November and December 2019, and March 2020, when Cx. tritaeniorhynchus adults were not presumed to be active. Moreover, JEV antigenomic RNA was detected in some JEV-positive tick samples, suggesting virus replication in ticks. However, taken together with no infectious virus isolated, the possibility that the antigenomic RNA was derived from the undigested bloodmeal source in ticks cannot be ruled out. Thus, the role of the ticks as a natural reservoir for JEV remains to be confirmed.
Analysis of Brucellosis Cases Between 2010 and 2020 in Guangdong Province, China
Authors: Wang Xiaoxiao , Zhao Yunhu , Liu Suling , Gu Bing
Published: April 2022

Brucellosis is a zoonotic disease with more than half a million people diagnosed worldwide. In China, 99% of cases were historically reported in the northern part of the country, and few were diagnosed in Guangdong province. Recently, Guangzhou has become as an emerging focus for brucellosis, with personal awareness of brucellosis and inexperience of clinicians hindering timely clinical diagnosis. To improve clinical management of this disease, we retrospectively analyzed 60 brucellosis cases from 2010 to 2020 in Guangdong Provincial People’s Hospital. There were no manifestation differences between southern and northern patients. However, 68.3% of patients lacked awareness of risk factors for Brucella infection. Therefore, to prevent its spread and avoid delays in diagnosis, implemented infected-animal control programs and enhanced education on brucellosis are necessary.
Case Report: Pulmonary Tuberculosis Accompanied by Pure Red Cell Aplasia and Autoimmune Hemolytic Anemia
Authors: Shimizu Hayato , Yamamoto Hiroshi , Hiramoto Nobuhiro , Nishioka Hiroaki
Published: April 2022

Tuberculosis is one of the most common infections worldwide. It has been associated with some hematologic disorders; however, pure red cell aplasia or autoimmune hemolytic anemia is rarely reported. We describe the case of a 68-year-old woman with pulmonary tuberculosis accompanied by pure red cell aplasia and autoimmune hemolytic anemia. These hematologic disorders were improved by treatment of pulmonary tuberculosis. This case suggests that physicians should consider the possibility of tuberculosis as a cause of pure red cell aplasia.
An Effective Barrier to Prevent Crop Contamination by Slug Vectors of Angiostrongylus cantonensis
Authors: Pang Lorrin , Coppolo Christy , Hauptman Sara
Published: April 2022

The accidental ingestion of slugs, intermediate hosts to the Angiostrongylus cantonensis parasite, is the most common cause of rat lungworm disease (RLWD) found in humans in Hawaii. This disease has high morbidity and can be complicated to diagnose and treat. With these considerations, efforts in prevention of the initial infection are of high priority. Management of the slug and snail population in food crops is a primary focus to reduce contamination of produce with the rat lungworm (RLW) parasite. The purpose of this study was to prevent RLW crop contamination by preventing the intermediate slug hosts from infesting produce. Our studies showed that an electrified metal tape was a very effective barrier first in the laboratory and then in a garden/farm setting. The intervention is simple to install and maintain and with monitoring for occasional barrier breaches should be able to significantly reduce slug invasion. An integrated pest management program will benefit from the addition of this barrier method to prevent slug carriers of RLWD from infesting produce.
Rosetting Responses of Plasmodium-infected Erythrocytes to Antimalarials
Authors: Lee Wenn-Chyau , Russell Bruce , Lau Yee-Ling , Nosten Francois , Rénia Laurent
Published: April 2022

In malaria, rosetting is a phenomenon involving the cytoadherence of uninfected erythrocytes to infected erythrocytes (IRBC) harboring the late erythrocytic stage of Plasmodium spp. Recently, artesunate-stimulated rosetting has been demonstrated to confer a survival advantage to P. falciparum late-stage IRBC. This study investigated the rosetting response of P. falciparum and P. vivax clinical isolates to ex vivo antimalarial treatments. Brief exposure of IRBC to chloroquine, mefloquine, amodiaquine, quinine, and lumefantrine increased the rosetting rates of P. falciparum and P. vivax. Furthermore, the ex vivo combination of artesunate with mefloquine and piperaquine also resulted in increased the rosetting rates. Drug-mediated rosette-stimulation has important implications for the therapeutic failure of rapidly cleared drugs such as artesunate. However, further work is needed to establish the ramifications of increased rosetting rates by drugs with longer half-lifves, such as chloroquine, mefloquine, and piperaquine.
Origin and Functions of Chinese Seasonal Festivals Qingmingjie and Chongyangjie
Authors: Hein Evelina
Published: April 2022

The article analyses the connection between Chinese folk calendar and the fundamental to the whole religious and social tradition of China ancestor worship. With the aim to clarify the role of folk calendar in the formation of the traditional culture, the author makes use of the  theory of the Chinese philosopher Li Zehou about the development stages of the mankind evolution and civilization as stages of a process of sedimentation. The article presents two examples with the seasonal festivals Qingming and Chongyang, both dedicated to the ancestor worship. Origin, development and functions of this festivals are traced in the context of the ancestor worship and the culture of the filial piety (xiao), based on the latter. The author uses the Dual Filial Piety Model, developed by Bedford and Yeh and creates a consequent model for describing the functions of the festivals Qingming and Chongyang as a binary complex of corresponding rituals. Thеse rituals are analysed as fulfilling basic psychological and social needs of the members of the Han ethnic community in connection to the specific background of the culture of filial piety (xiao).
1D and 2D NMR spectra of coffee from 27 countries
Authors: Osorio Javier , Arana Victoria A. , Medina Jessica M. , Alarcon Rodrigo , Moreno Edgar , Wist Julien
Published: April 2022

Between 2012 and 2014, 715 green coffee samples were gathered by Almacafé S.A. (Bogotá, Colombia) from 27 countries. These were analysed at the nuclear magnetic resonance (NMR) laboratory at Universidad del Valle (Cali, Colombia). Over 1000 methanolic coffee extracts were prepared and 4563 spectra were acquired in a fully automatic manner using a 400 ﻿MHz NMR spectrometer (Bruker Biospin, Germany). The dataset spans the variance that could be expected for an industrial application of origin monitoring, including samples from different harvest times, collected over several years, and processed by at least two distinct operators. The resulting 1D and 2D spectra can be used to develop and evaluate feature extraction methods, multivariate algorithms, and automation monitoring techniques. They can also be used as datasets for teaching, or as a reference for new studies of similar samples and approaches.
Взаимосвязь величины макросейсмической интенсивности с показателями инструментальных записей Гоубанского землетрясения 2000 г. и Тбилисских землетрясений 2002 г.
Authors: Заалишвили В.Б. , Мельков Д.А. , Фидарова М.И.
Published: April 2022

Сейсмическое воздействие традиционно оценивают на основе данных инженерного макросейсмического обследования последствий сильных и разрушительных землетрясений. Являясь объективной характеристикой выделенной сейсмической энергии величина макросейсмической интесивности должна иметь связь с инструментальными параметрами сейсмических колебаний. Для оценки воздействий в ближней зоне землетрясений требуются инструментальные записи. И, хотя в мире в силу развития сетей сильных движений накоплено много записей, на Кавказе имеются только отдельные записи сильных движений, тем более подкрепленные результатами детального макросейсмичекого обследования. В этой связи записи землетрясений, полученных в 2000, 2002 гг. на территории г.Тбилиси являются уникальными. Целью работы является установление энергетических показателей сейсмического воздействия на основе инструментальных записей землетрясений различной интенсивности и энергоемкости различных видов конструкций проявляющихся в итоговом макросейсмическом проявлении. Методы работы. Параметры записей рассчитывались по общепринятым методикам, предложенным различными авторами: интенсивность Ариаса, кумулятивная абсолютная скорость, интенсивность Анга, интенсивность Хаузнера, мера Fajfar, мера полной энергии, площадь реального спектра, а также средневзвешенные частота, период колебаний и продолжительность. Сопоставление результатов выполнялось методами регрессионного анализа. Результаты работы. В результате установлено наилучшее соответствие реального проявления землетрясений параметрам, описывающим энергетические характеристики сигнала. При этом рассмотрены различные частотные диапазоны. Все используемые оценки инструментальной интенсивности основаны на горизонтальной компоненте, однако в ближней зоне, как показал анализ записей Тбилисских землетрясений, велико проявление вертикальной составляющей. Вероятно, разрабатываемая мера инструментальной интенсивности дожна содержать комбинацию обоих компонент.
Design of an Automated Over-bed Hospital Meal Cart for Public Hospitals
Authors: Ayodeji Sesan P
Published: April 2022

Hospital meal carts are used to deliver meals, drugs and some other materials to patients in the hospital environment. These carts which are moved manually by operators, the health workers, mostly do not comply with ergonomics guidelines and physical requirements of the equipment users in terms of anthropometry data of the region thus increasing the risk of musculoskeletal disorder among the meal cart users. Based on the preliminary study, most operators expressed the feeling of fatigue and postural discomfort in the shoulders, arms, back and thighs as a result of moving the hospital meal cart around the hospital environment. Also, patients who are limited in terms of sitting and standing needs this for their comfort and assistant. In order to ease this discomfort, an automated over-bed hospital table was designed using the adult working class anthropometry data of Nigeria. The cart has an adjustment feature of forth and back movement as well as height adjustment mechanism to suite the use of the patient. The responses obtained from ergonomic evaluation of the re-designed hospital meal carts were analyzed using SPSS to obtain the non-parametric Chi-Square test as well as the median and interquartile range. The test however showed significant difference when p < 0.050, hence the redesign is justified. The table can be operated by the patient with little or no assistance hence will reduce fatigue and risk of musculoskeletal disorder among the meal cart users. Keywords— Anthropometric data, Discomfort, Ergonomics, Hospital and Meal cart.
Komposit Porous Material Berbahan Polylactic Acid (PLA)
Authors: Aji Saputro Tegar , Syahbuddin Syahbuddin
Published: April 2022

3D Printing ialah evolusi dari teknologi cetak, yaitu sanggup menciptakan ataupun memproduksi serta merancang struktur yang mutahir dalam satu kesatuan. 3D Printing merupakan salah satu proses fabrikasi Fused Deposition Modelling (FDM) yaitu teknologi Additive Manufacturing (AM) yang sistem kerjanya, pembentukan benda dengan akumulasi bahan lapis demi lapis. Dari latar belakang masalah diatas, identifikasi permasalahan yang hendak dijadikan bahan riset merupakan dilakukannya pengujian filament 3D printer dengan material Polylactic Acid (PLA), khususnya dengan variasi kecepatan cetak poros material. Penelitian ini memiliki tujuan untuk mengetahui hasil uji yang dilakukan pada filament jenis Polylactic Acid (PLA) dengan mengetahui kekuatan dan pengaruh yang akan diuji dengan membuat spesimen uji terhadap kekuatan uji tarik, struktur makro serta uji takik (impact)
Kajian Kapasitas Sambungan Plat Buhul Struktur Portal Pylon Jembatan Gantung Menggunakan Software Idea Statica
Authors: Sirait Surung , Tarigan Johannes , Perwira Mulia Ahmad
Published: April 2022

Bagian terlemah dari suatu sistem struktur baja terletak pada bagian sambungannya. Sambungan dapat berupa pelat buhul maupun pelat penyambung. Oleh sebab itu sambungan harus dirancang lebih kuat dan daktail dari komponen struktur yang merangka pada sambungan tersebut, seperti ditetapkan dan dijelaskan pada berbagai standar atau peraturan.  Jembatan JUDESA  merupakan solusi teknologi terkait jembatan untuk membuka aksesibilitas masyarakat desa melalui penyediaan infrastruktur jembatan sederhana yang mudah dibangun, efektif, dan efisien. Tujuan dari penelitian ini adalah mengetahui kapasitas dan klassifikasi sambungan struktur pylon jembatan gantung JUDESA pada Jembatan Pisang Binaya khususnya sambungan antar segmen kolom pylon berdasarkan kekuatan dan kekakuan sambungan akibat gaya-gaya dalam yang terjadi setelah penambahan kombinasi beban gempa sesuai dengan peraturan/code gempa yang terbaru SNI 1726-2019. Penelitian ini dilakukan dengan  kajian secara numerik menggunakan analisis elemen hingga (finite element) dengan memodelkan jembatan secara utuh (jembatan gantung) dengan menggunakan software SAP 2000 Versi 14.2.2 dengan beban layan operasional dan juga beban gempa. Proses analisa pada sambungan dilakukan dengan bantuan software IDEA StatiCa. Berdasarkan hasil analisis yang telah dilakukan maka dapat disimpulkan bahwa profil, plat penyambung dan juga  baut pada jembatan JUDESA  masih jauh dari kemampuan maksimum dari semua komponen penyambung (baut, pelat, dan profil). Hasil finite element menunjukkan bahwa tegangan yang terjadi sebesar 37,7 mPa, ini menunjukkan bahwa tegangan yang terjadi hanya sekitar 15 % dari kemampuan bahan penyambung baik pelat penyambung maupun profil yang disambung. Gaya tarik yang terjadi pada baut maksimum sebesar 0,2 kN, dan geser maksimum yang terjadi pada baut sebesar 1,1 kN ini menunjukkan bahwa gaya tarik dan geser  yang terjadi pada baut hanya sekitar 0,1 % dari kemampuan bahan baut.
Dampak Alih Fungsi Lahan Terhadap Keberlanjutan Suplai Air Bersih dalam Menjaga Ekosistem Darat
Authors: Putri Anisah Amelia , Borami Ju Ade , Tng Angel , Zikra Elvira , Carolina Weley Nadia , Fitri Winda
Published: April 2022

Perkembangan zaman yang begitu pesat menyebabkan pemerintah harus melakukan alih fungsi lahan hutan untuk menunjang pembangunan hingga pertumbuhan penduduk. Penggunaan lahan oleh setiap kegiatan pembangunan akan mengubah tatanan lingkungan hutan menjadi tatanan lingkungan baru yang mengakibatkan perubahan pada kelestarian lingkungan seperti penurunan kualitas air bersih yang nantinya akan berbahaya bagi kehidupan habitat tertentu dalam ekosistem yang terkena dampak. Penelitian ini bertujuan untuk mengetahui dampak dari alih fungsi lahan dan juga peran dari SDGs ke-6 dan ke-15 terhadap keberlanjutan suplai air bersih.  Metode yang digunakan dalam penelitian ini adalah penelitian hukum normatif dengan teknik pengumpulan data yang dilakukan melalui studi kepustakaan. Hasil penelitian ini menunjukkan bahwa alih fungsi lahan memberikan dampak bagi mahkluk hidup, dampak tersebut dapat memengaruhi penurunan kualitas lahan yaitu berupa kegiatan yang dilakukan oleh manusia seperti dilakukannya cara tebang bakar (slash and burn). Kegiatan tersebut dapat mempercepat proses pencucian dan penipisan lapisan tanah sehingga berkurangnya kadar organik tanah yang akan berakibat pada buruknya sifat fisik dan kimia tanah
Analisis Du Pont System dalam Mengukur Kinerja Keuangan Perusahaan Sub Sektor Cosmetic and Household
Authors: Cahya Sagala Indah , Rahman Fauziah
Published: April 2022

Kinerja perusahaan tergantung dari operasional perusahaan dan kinerja perusahaan dapat dilihat melalui laporan keuangan. Laporan keuangan dapat dijadikan alat ukur untuk menganalisis kinerja perusahaan tersebut baik atau tidak. Penelitian ini bertujuan untuk mengetahui kinerja keuangan perusahaan sub sektor cosmetic and household di Indonesia yang terdaftar di Bursa Efek Indonesia Tahun 2015 – 2019 dengan pendekatan Du Pont System secara Time Series Approach (TSA) dan Cross Sectional Approach (CSA). Analisis ini bersifat lebih menyeluruh dan dapat mengetahui seberapa kuat hubugan penggunaan hutang, perputaran aktiva, marjin laba serta ROI terhadap ROE. Penelitian ini merupakan penelitian deskriptif kuantitatif. Hasil penelitian ini menunjukkan analisis Return On Investment (ROI) dan Return On Equity (ROE) dengan Time Series Approach (TSA) pada Tahun 2015 sampai dengan 2019 mengalami penurunan dan fluktuatif. Analisis Du Pont System secara Cross Sectional Approach (CSA) pada industri perusahaan sub sektor cosmetic and household di Indonesia sebesar 3.428%. Hal ini menunjukkan bahwa secara keseluruhan dikatakan perusahaan sub sektor cosmetic and household berkinerja BAIK.
Prioritas Penanganan Jalan Nasional Menggunakan Metode AHP dan ANP: Ruas Jalan Batas Kota Rantau Prapat- Aek Nabara
Authors: Simanjorang Alboin , Perwira Mulia Ahmad , Anas Ridwan
Published: April 2022

Prioritas penanganan jalan didasarkan pada pertimbangan yang kompleks dengan mengakomodasi aspek yang bersifat teknis dan nonteknis. Pendekatan yang dapat mengakomodasi aspek yang bersifat multikriteria adalah Analytic Hierarchy Process (AHP) dan Analytic Network Process (ANP). AHP merupakan pendekatan yang bersifat preferrence dengan model yang berbentuk hirarki, sedangkan ANP merupakan pendekatan yang bersifat influence dengan model yang berbentuk jaringan. Tujuan dari penelitian ini adalah menentukan prioritas penanganan ruas jalan Batas Kota Rantau Prapat – Aek Nabara – Sp. Kota Pinang – Bts. Propinsi Riau dengan menggunakan metode AHP dan ANP menggunakan 4 (empat) kriteria. Data hasil analisis menunjukkan  bahwa dari 4 (empat) kriteria yang diambil dalam penelitian ini dengan mengunakan metode AHP yakni faktor kondisi jalan (0,523)  merupakan kriteria yang paling dominan, diikuti faktor biaya (0,261), faktor lalu lintas (0,141) dan kebijakan (0,075).  Selanjutnya untuk memperoleh bobot akhir yang lebih objektif dilakukan analisis dengan metode ANP karena memungkinkan dilakukan feedback terhadap elemen dan klasternya sendiri yakni faktor kondisi jalan (0,4138) merupakan kriteria yang paling dominan, diikuti faktor biaya (0,2566), faktor lalu lintas (0,1846) dan kebijakan (0,1450). Berdasarkan hasil analisis dalam penentuan urutan prioritas dengan metode AHP, maka dapat diurutkan prioritas penanganan jalan nasional yaitu Ruas Batas Kota Rantau Prapat – Aek Nabara menjadi prioritas pertama kemudian diikuti Ruas Sp. Kota Pinang – Bts. Provinsi Riau dan Ruas Aek Nabara – Sp. Kota Pinang. Selanjutnya untuk mendapatkan hasil yang lebih stabil dan lebih akurat dalam penentuan urutan prioritas digunakan metode ANP dan didapatkan hasil yaitu Ruas Batas Kota Rantau Prapat-Aek Nabara menjadi prioritas pertama kemudian diikuti Ruas Sp. Kota Pinang-Bts. Provinsi Riau dan Ruas Aek Nabara-Sp. Kota Pinang. Perolehan urutan prioritas penanganan jalan dengan metode AHP pada penelitian ini sama hasilnya dengan menggunakan metode ANP.
Hukum Usaha Kecil Menengah dan Dasar Perjanjian Hukum
Authors: Arbani Muhammad
Published: April 2022

Penulisan artikel ini membahas masalah hukum bagi UMKM dan menengah (selanjutnya disebut UMKM) dan dasar perjanjian hukum. Hal ini dilatari pentingnya memahami aspek hukum UMKM dan dasar perjanjian berkaitan dengan perlindungan hukum bagi pelaku UMKM itu sendiri.  Makin pesatnya pertumbuhan UMKM dalam beberapa tahun belakangan ikut meningkatkan potensi konflik hukum di lingkup pelaku UMKM khususnya berkaitan dengan kontrak bisnis atau perjanjian-perjanjian hukum yang lahir dari kegiatan usahanya. Sementara, bagian dari kegiatan bisnis adalah terciptanya Produk komersial, pada akhirnya perlu melindungi kekayaan intelektual dari persaingan tidak sehat. Kekayaan intelektual menjadi pertanyaan penelitian yang semakin menarik karena menentukan percepatan pembangunan nasional di era globalisasi
Effect of Bonds Maturity Date, Interest Rates, Inflation, Exchange Rates and Foreign Exchange Reserves on Yield To Maturity of Government Bonds 2014-2020
Authors: Varirahartia Ditha , Santoso Marsoem Bambang
Published: April 2022

This study aims to analyze the effect of maturity date, interest rate, exchange rate, inflation and foreign exchange reserves on the yield to maturity of Indonesian government bonds for the period 2014-2020. The analysis is using panel data analysis. The results showed that the maturity level of bonds (X1), interest rates (X2), had a positive and statistically significant effect on yield to maturity. The inflation (X3) and has a negative and significant effect, while the exchange rate (X4) has no significant effect but has a positive relationship.  Foreign exchange reserves (X5) have a negative and significant effect. The exchange rate does not have a significant effect. This is not in accordance with the previous theory, because the sample limitation in this study only uses bonds with Rupiah currency
Analisa Kecelakaan Kerja Pada Di PT Cipta Unggul Karya Abadi dengan Metode Job Safety Analysis (JSA) dengan Pendekatan Failure Mode And Effect Analysis (FMEA)
Authors: Wijaya Indra
Published: April 2022

PT Cipta Unggulkarya Abadi  adalah PT yang bergerak dibidang pembuatan stapingpart mobil, Dalam proses produksi nya yang banyak menggunakan mesin dan alat-alat berat seperti mesin bubut, mesin milling,las, dan mesin gerinda terdapat potensi dan bahaya yang dapat menimbulkan kecelakaan pada operator/karyawan. Penelitian ini dilakukan dengan pengukuran kegagalan pada setiap aktivitas yang ada di PT cipta unggul karya abadi, pengukuran dilakukan pada setiap mesin yang ada di area bengkel tersebut.  Pengolahan data dilakukan dengan menghitung tingkat kegagalan, efek kegagalan, tingkat kejadian, lalu menentukan tingkat deteksi dan menghitung nilai RPN untuk menentukan prioritas mana yang harus diambil dengan menggunakan metode Job Safety Analysis dengan pendekatan Failure Mode And Effect Analysis. Hasil penelitian Terdapat  kecelakaan kerja yang di PT Cipta unggul karya abadi, Tangan tersayat ulir bubut, Tersayat material tajam, Tersandung besi, Mata terkena ampas proses pembubutan, Kejatuhan material besi, Mata terkena gram gerinda, Tersayat mata gerinda, Tersayat material yang tajam, Tangan terkena serpihan gram gerinda yang panas, Tersandung kabel gerinda, Tangan tersayat mata pahat/ end mill, Tangan terkena serbuk panas dari proses milling, Terbentur body mesin, Tersayat sudut tajam benda kerja, Tertimpa benda kerja. Usulan perbaikan yang dapat diberikan adalah menambahkan beberapa alat pelindung diri yang sesuai dengan pekerjaan dan lingkungan bengekel, operator harus menggunakan kacamata pengaman, pelindung wajah, penutup telinga masker, sarung tangan pengaman, sepatu pengaman
Efektivitas Model Think Talk Write Dalam Pembelajaran Menulis Teks Eksplanasi Siswa Kelas XI UPT SMA Negeri 16 Bone
Authors: Safar Muh
Published: April 2022

Penelitian ini bertujuan untuk mendeskripsikan efektivitas model Think Talk Write dalam pembelajaran menulis teks eksplanasi siswa kela XI SMA Negeri 16 Bone. Jenis penelitian yang digunakan adalah eksprimen dengan teknik pengumpulan data yaitu tes dan non tes (pengamatan). Populasi dalam penelitian ini adalah kelas XI yaitu kelas XI IPS 1 sebanyak 30 dan kelas XI IPS 2 sebanyak 30.  Untuk mengetahui efektivitas model Think Talk Write maka dipilih dua kelas yaitu kelas eksprimen dan kelas kontrol. kelas eksprimen mendapat pelakuan model Think Talk Write sedangkan kelas control  tidak menggunakan model. Hasil penelitian ini menggunakan uji t.  Data yang disajikan diperoleh angka sebesar t-hitung  12,351 sedangkan t-tabel  dengan dk 58 sebesar 2,002 sehingga t-hitung >  t-tabel yaitu 12,351  > 2,002. Berdasarkan perhitungan maka dapat dikatakan Ha diterima. Analisis akhir kemampuan menulis teks eksplanasi dengan mode Think Talk write pada siswa kelas XI SMA Negeri 16 Bone terdapat adanya perbedaan nilai rata-rata antara kelas eksprimen dan kelas control. Dengan demikian dapat disimpulkan bahwa model Think Talk Write efektif digunakan dalam pembelajaran menulis teks eksplanasi pada siswa kelas XI SMA Negeri 16 Bone.
Practice and Theory: Ten Lessons that I Have Learned about Being a Vice Principal
Authors: Irvine Jeff
Published: April 2022

The vice principal has the potential to significantly influence everyone in the school building. The expertise required to effectively carry out the duties of the role include interpersonal skills, leadership skills, reflective practice, and knowledge of the current research in the field of education. The position of vice principal requires a skillful blend o f practice and theory to successfully maximize the role’s impact on students and staff. Foremost among the necessary skills is interpersonal relationships, as the majority of the vice principal’s activities involve interactions with students, staff, parents, support staff, and members of the community. While often viewed as a preparatory stage prior to becoming a principal, the vice principal position has a significant impact on the lives of many people. It is therefore important that the vice principal build a repertoire of skills and knowledge in order to maximize the positive impact that the vice principal exerts. To that end, this paper describes 10 lessons the author learned as a vice principal in Ontario, Canada, and the theory underpinning those lessons that also had to be learned in order to make the role as effective as possible. This blending of theory and practice is imperative for the vice principal’s role to be as effective as possible for students and educational institutions. This paper provides a practitioner’s viewpoint of how theory supports practice. While functioning in the role, the author had the opportunity to impact the lives of a large number of students and staff. In addition, the author learned a great deal about current research and how it applies to the role of vice principal. By typifying the role of lifelong learner, a vice principal can maximize their impact while also serving as a role model for aspiring school administrators.
Diagnóstico da Restauração: Um método para desenvolver estratégias de restauração de paisagens e florestas por meio da avaliação rápida de fatores-chave de sucesso
Authors: Hanson Craig , Buckingham Kathleen , DeWitt Sean , Laestadius Lars
Published: April 2022

O Diagnóstico da Restauração foi desenvolvido pelo World Resources Institute (WRI) e pela União Nacional para a Conservação da Natureza (IUCN) como uma ferramenta complementar à Metodologia de Avaliação de Oportunidades de Restauração (ROAM), com o objetivo de apoiar atores locais e tomadores de decisão a determinar o status das condições favoráveis para o estabelecimento de políticas, práticas e medidas para uma restauração de paisagens e florestas bem-sucedida.
Pelatihan Pembuatan Lilin Aromaterapi Berbahan Baku Kopi Pada Ibu PKK di Dusun Krajan, Patrang
Authors: Pratita Dian Galuh , Selviyanti Erna , Sabran Sabran
Published: April 2022

In addition, the culture of using coffee as a drink has existed since ancient times and is carried out both at the household and community level. The benefits of coffee are increasingly being noticed during this pandemic, along with the many diversification of coffee products, this service is carried out by making aromatherapy candles with waste coffee raw materials in the form of ground coffee as the main ingredient. Imperfectly broken coffee which does not pass the market is generally marketed at a low selling price at the household level. Therefore this service is carried out for PKK women as an effort to improve coffee processing skills into other products. The service will be held in August 2021 using direct practice methods and offline presentation of material with representatives from PKK Dusun Krajan, Patrang District. Based on the results obtained that there is a change in both the knowledge and skills of the participants. Prior to participating in the training, the participants did not know the benefits of coffee and other preparations besides coffee drinks, but after participating in the training, the participants became more aware of the benefits and variety of preparations made from coffee, especially aromatherapy candles made from coffee. In addition, on the skill side, it also increased, where before the training the participants did not have the skills to process aromatherapy candles, after the training the participants became confident to make aromatherapy candles independently.
Determination of Cr (III) and Cr (VI) In Water by Selective Separation and Preconcentration on Hybrid Resin
Authors:   High Instituteof Science and Medical Technology-Abo-Saliem, Issa Nureddin Ben
Published: April 2022

Abstract Simple and rapid method has been developed for separation, preconcentration and determination of Cr(III) and Cr(VI) species in water by using selective hybrid R-Cu-(OH)2 resin (HCR). The effect of pH value on the adsorbed of Cr(VI) was investigated, Cr(VI) species can be retained on the HCR and eluted by 1.0 M of NaOH solution completely while Cr(III) can not adsorbed on HCR. Chromium species before and after separation process were measured with 1-5-diphenylcarbazide by using spectrophotometer. The results showed that the capacity of HCR on adsorbed of Cr(VI) was 3.43 mg g-1. The concentration of Cr(V) determined by different between total Cr and Cr(III). The recovery of the determination of Cr(III) and Cr(VI) were ( 93.0 % to 101% ) and (93.6 % to 105 % ) respectively , while the RSD were ( 0.99% -6.18% ) and ( 1.63%-7.3% ) for Cr(III) and Cr(VI) respectively.
The Effect of Robotics Program on Students Attitude Towards Science
Authors: Muniandy Thiwagar , Sharif Sabariah , Mariappan Muralindran
Published: April 2022

The purpose of this research is to study the effect of robotics program on students attitude towards science. A total of 374 year 6 students (12years old) involving 10 primary schools from Malacca and Selangor have participated in this study. The researcher used Test of Science Related Attitudes (TOSRA) questionnaire developed by Fraser (1981) to measure students attitude towards science. In this study the researcher used a non-survey quantitative approach method with a quasi- experimental design involving treatment and control group. The changes in students attitude towards science was measured in three different times involving pre-test, post-test 1 and post-test 2. The researcher has performed two inferential statistical test, Repeated Measures Analysis of Variance (ANOVA) and One-way Analysis of Covariance (ANCOVA) at significant level of
Pengaruh Berita Kecelakaan Pesawat Sriwijaya Airsj 182 di Media Internet terhadap Citra Jasa Maskapai Sriwijaya Air:
Authors: Novita Novita
Published: April 2022

This study aims to identify and measure the impact of the effect of the news a plane crash sriwijaya water SJ 182 in the internet media on the image of the Sriwijaya Air airline, especially for airline customers, including the cadets at the Yogyakarta Aerospace Technology College. This study uses a quantitative approach method. Data collection techniques are carried out by distributing questionnaires and documentation. In proving and analyzing this, validity and reliability tests are used, simple linear regression test and T test. The results of the test show that: 1) There is a significant effect of the variable influence of the Sriwijaya Air 182 plane crash news on the internet on the service image variable. Sriwijaya Air. 2) News of the Sriwijaya Air SJ 182 plane crash on the internet has little effect on the image of Sriwijaya Air's services, which is 31.6%.

 

Keywords : Sriwijaya Air, News, Image

 

Penelitian ini bertujuan untuk mengetahui dan mengukur seberapa besar dampak pengaruh berita kecelakaan pesawat sriwijaya air SJ 182 di media internet terhadap citra jasa maskapai sriwijaya air khususnya bagi pelanggan perusahaan penerbangan termasuk para Taruna di Sekolah Tinggi Teknologi Kedirgantaraan Yogyakarta. Penelitian ini menggunakan metode pendekatan kuantitatif. Teknik pengumpulan data dilakukan dengan pembagian kuesioner dan dokumentasi. Dalam membuktikan dan menganalisis hal tersebut, maka digunakan uji validitas dan reliabilitas, uji regresi linear sederhana serta uji T. Hasil dari pengujian menunjukkan bahwa : 1) Terdapat pengaruh yang signifikan dari variabel pengaruh berita kecelakaan pesawat Sriwijaya Air 182 di media internet terhadap variabel citra jasa maskapai Sriwijaya Air. 2) Berita kecelakaan pesawat Sriwijaya Air SJ 182 di media internet berpengaruh kecil terhadap citra jasa Maskapai Sriwijaya Air yaitu sebesar 31,6 % .

 

Kata Kunci : Sriwijaya Air, Berita, Citra
LINGVOGENDERAL BASIS OF «MAN» IMAGE IN THE PAREMIOLOGICAL WORLD
Authors:   Candidate of Philological Sciences, Associate Professor, Khoja Akhmet Yassawi International Kazakh-Turkish University, ISSAYEVA Zh.I.
Published: April 2022

In this article, the binary pair «Woman: Man», which constitutes the gender characteristic of the macro system «Man», an integral part of the triad «Man-Society-Nature», in the paremiological image of the world is divided into two separate, independent concepts – «Woman» and «Man». In Kazakh paremiology linguistic characteristics of the concepts «woman» and «man» is provided by the integrity of multilevel micro-frame items of social, socio-ritual, socio-psychological content, reflecting the relationship of social status roles «boy – girl», «father» – «mother», «girl» – «guy», «bride» – «groom», «woman» – «man» and others. As a result of inter-branch communication between the image of a man with «masculine traits» formed in ethnic consciousness and the image of a woman with «feminine traits» is the image of a «Man» in the language which has been passed through the «sieve» of national culture. It is determined that gender is the result of a culture that reflects the idea of feminine tenderness and masculine courage, embedded in the traditions, customs, folklore and language of the people. It is assumed that in the collective consciousness of the ethnogenetic community there are gender stereotypes in any case, i.e. simplified or expanded concepts about the characteristics and peculiarities of women and men. Gender linguistics is a new scientific direction in linguistics, which arose in connection with the study of differences in the use of words by men and women in Kazakh linguistics. In the linguistic picture of the world, it is proved that the «female» and «male» signs of the binary pair «woman-man» are marked as a qualitative indicator of the conceptual apparatus of the «Man» macrosystem.
EFFECTIVENESS OF BLENDED LEARNING IN HOTS FOR SCIENCE IN ELEMENTARY SCHOOL
Authors:   Muria Kudus University, IDAWAT T. , MURTONO  ,   Muria Kudus University, UTAMININGSIH S. ,   Muria Kudus University, SULEIMEN S.B. ,   Abai Kazakh National Pedagogical University
Published: April 2022

The purpose of this study was to determine the effectiveness of blended learning on HOTS (Higher Order Thinking Skills) for fifth-grade students in science learning. This study uses experimental research methods. The subjects in this study were fifth-grade students at Public Primary School Number 2 Rejosari and Public Primary School Ngegot with 56 students as the experimental class and Class V at Public Primary School Number 1 and 3 Rejosari in Mijen Demak District with 46 students as the control class. The effectiveness of this blended learning model can be seen from the results of the N-Gain score test where the experimental class has an average increase in student learning outcomes of 0.43 in the medium category and the control class in the low category with an average of 0.15. While the results of the Wilcoxon test are known as Asymp.Sig. (2-tailed) is worth 0.000. So, it can be concluded that there is a difference between the pre-test and post-test learning outcomes of the experimental and control classes. These differences were analyzed by the Mann-Whitney Test. Based on the Mann-Whitney test, it is known that the value of Asymp.Sig. (2-tailed) of 0.000 is smaller than < 0.05 probability value. So, it can be concluded that there is a HOTS difference between the experimental and control classes, where the average of the experimental group is more than the average of the control group. It can be concluded that the application of blended learning has a significant impact on student HOTS in science lessons for grade V elementary.