bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the Suffosion Risk for the Final in-Situ Slopes of the North Peşteana Open-Pit
Authors: Apostu Izabela-Maria , Lazăr Maria , Faur Florin
Published: April 2021

With the occasion of complex and detailed studies, conducted especially from the geotechnical point of view (between 2016 and 2019), on the North Pesteana mining perimeter (more precisely on the lignite open-pit with the same name) numerous areas affected by suffosion were highlighted, mainly located on the lower steps (steps III and IV). Starting from these observations, the present paper analysis the risk of suffosion phenomenon to occur in the case of the final slopes of North Pesteana open-pit. In general, as observed, these areas have small and medium sizes, and do not affect significantly the stability of the steps, being immediately remedied with the advancement of the work front. Also, it was observed that, with the advancement of the excavation fronts, the groundwater currents constantly entrain the fine particles from the aquifer formations, and therefore new such suffosion areas occur. Taking into account the fact that the exploitation of lignite in this perimeter is ending soon, it was considered as necessary to assess the risk of suffosion at the final slopes (long term slopes) in order to be able to identify appropriate measures to prevent future potential catastrophic events.
2018 Chinese guidelines for the diagnosis and treatment of rheumatoid arthritis
Authors: Tian Xinping , Wang Qian , Li Mengtao , Zhao Yan , Zhang Zhiyi , Huang Cibo , Liu Yi , Xu Huji , Chen Yaolong , Wu Lijun , Su Yin , Xiao Weiguo , Zhang Miaojia , Zhao Dongbao , Sun Linyun , Zuo Xiaoxia , Lei Junqiang , Li Xiaofeng , Zeng Xiaofeng
Published: April 2021

A multidisciplinary guideline development group was established to formulate this evidence-based diagnosis and treatment guidelines for rheumatoid arthritis (RA) in China. The grading of recommendations, assessment, development, and evaluation (GRADE) system was used to rate the quality of the evidence and the strength of recommendations, which were derived from research articles and guided by the analysis of the benefits and harms as well as patients’ values and preferences. A total of 10 recommendations for the diagnosis and treatment of RA were developed. This new guideline covered the classification criteria, disease activity assessment and monitoring, and the role of disease modifying antirheumatic drugs (DMARDs), biologics, small molecule synthetic targeting drugs, and glucocorticoids in the treat-to-target approach of RA. This guideline is intended to serve as a tool for clinicians and patients to implement decision-making strategies and improve the practices of RA management in China.
Actual Problems of Appealing Decisions, Actions (Inaction) of Customs Authorities of the Russian Federation and Their Officials
Authors: Kolesnikov I.V. , Chepurnaya I.V.
Published: April 2021

Рассматривается институт обжалования решений, действий (бездействия) таможенных органов и их должностных лиц. Проводится анализ предусмотренных действующим законодательством порядков обжалования: судебного и административного. Выделены проблемы, связанные с применением разных порядков обжалования решений, действий (бездействия) таможенных органов и их должностных лиц. Подчеркнута необходимость совершенствования нормативно-правовой базы, выработки единообразных подходов к порядку рассмотрения жалоб таможенными органами.
Problems of Training Customs Officials in the Direction of the CCFRM and Ways to Solve Them
Authors: Borisenko A.V.
Published: April 2021

Рассматриваются вопросы подготовки должностных лиц таможенных органов по направлению ТКДРМ на примере деятельности Учебного центра таможенного контроля делящихся и радиоактивных материалов Владивостокского филиала Российской таможенной академии. Анализируются основные проблемы и предлагаются пути их решения. Th e article deals with the issues of training customs offi cials in the direction of CCFRM on the example of the Training Center for Customs Control of Fissile and Radioactive Materials of the Vladivostok branch of the Russian Customs Academy. Th e main problems are analyzed and ways of their solution are suggested.
Historical and Legal Aspects of Some Issues of Customs Law Taught in Universities
Authors: Vityuk V.V.
Published: April 2021

Анализируются и комментируются историкоправовые аспекты некоторых вопросов таможенного права (его отдельных правовых институтов), преподаваемого в вузах в рамках различных учебных дисциплин по специальности «Таможенное дело». Отмечается значимость знания истории вопроса при формировании (проектировании) его современного состояния для использования в различных областях деятельности, в том числе образовательной. Th e article analyzes and comments on the historical and legal aspects of some issues of customs law (its separate legal institutions), taught in universities within the framework of various academic disciplines in the specialty “Customs”. Th e importance of knowledge of the background in the formation (design) of its current state for use in various fi elds of activity, including education, is noted.
On the Main Results of the Work of the Vladivostok Branch of the Russian Customs Academy in 2020
Authors: Dyakov V.I.
Published: April 2021

Отражены итоги и проблемы, с которыми Владивостокский филиал Российской таможенной академии столкнулся в 2020 г. при реализации программ высшего образования, дополнительного профессионального образования (ДПО), в других видах деятельности. Показано, что в непростых условиях вузу удалось успешно справиться со поставленными задачами. Th e article refl ects the results and problems that the Vladivostok branch of the Russian Customs Academy faced in 2020 when implementing programs of higher education, further vocational education (FVE), and in other types of activities. It is shown that in diffi cult conditions the university managed to successfully cope with set tasks.
Review of Research on the Impact of the COVID-19 Pandemic on the Development of Global and Russian E-commerce
Authors: Goncharuk I.V.
Published: April 2021

Th e article demonstrates the changes that have occurred in the dynamics and structure of international online commerce, describes how the customs preferences have changed under the infl uence of the pandemic. An adjustment of the estimates of the prospects for the development of global and Russian e-commerce is given.
Comparative Analysis of Indirect Taxation in the EAEU Countries
Authors: Filatova V.V.
Published: April 2021

Проведен анализ особенностей применения таможенных налогов в странах ЕАЭС, а также количества и размера ставок и предоставляемых льгот, установленных законодательствами стран ЕАЭС при взимании акциза и НДС. Выявлена разница в ставках косвенных налогов, создающая неравные конкурентные условия для ввоза товаров на территорию ЕАЭС.
Food as Power
Authors: Choi Kiana
Published: April 2021

This paper is a critical analysis through a close reading of Eden Robinson’s short story, “Traplines” that addresses the topic of Indigenous identity, particularly the identity of Indigenous youth in the wake of the parents’ generation residential school experience.  Robinson’s story focusses on the life of a teenaged Indigenous boy called Will, who is exposed to family violence and substance abuse, going to school in town. I argue that the text emphasizes the colonizing nature of non-Indigenous interference in the lives of families like Will's as proof of continuing colonization. Will's English teacher and other white characters use their white privilege in and outside of places of consumption as representations of power in the text. The result of this imbalance of power is the development of a confusing fragmentation of identity in the Indigenous youth. In its discussion of Will’s confusion, the text raises questions about the nature of education.
3 Minute Thesis: “One slide, no props, 3 minutes”
Authors: Jamieson Brandon , Krauss Elisha , Preobrazenski Nick
Published: April 2021

Student participants present their research and its wider impact in 3 minutes or less to a panel of non-specialist judges:
3. Hybridization between Thick-billed and Common Murres
Authors: Colston-Napali Lila
Published: April 2021

Thick-billed and common murres are migratory seabirds that breed in colonies in the North Pacific and North Atlantic oceans. Despite these sister species diverging 6.5 million years ago, they have been found to hybridize. In this study, hybridization between thick-billed and common murres was investigated in 15 Atlantic colonies of murres. Some colonies were single species colonies, and at other colonies both species breeds. DNA from wing samples collected from the annual murre hunt in Newfoundland and Labrador was also analyzed. Restriction-site associated DNA sequencing was performed on the samples, identifying single nucleotide polymorphisms throughout the genome. The program STACKS was used to identify and genotype loci. Software such as STRUCTURE was used to investigate admixture between the two populations. 32 of 166 common murres and 26 of 188 thick-billed murres were identified as hybrids. This totaled to 16% of the samples, a higher proportion of hybrid murres than found in previous studies of Pacific colonies. Interestingly, a significantly larger proportion of hunted than non-hunted birds were identified as hybrids. Furthermore, hybrid individuals were found at both shared colonies, and those where only one species breeds. As top predators that are threatened by human-mediated activities such as hunting and oil pollution, and that may be vulnerable to climate change, research into the hybridization of murres has numerous conservation implications. Currently, there is uncertainty of the impact hybridization will have on the murre populations, and research into the rate and trends of hybridization is of importance.
4. Amber-guitity: A coming of Age Tail
Authors: Handyside Ellen
Published: April 2021

Vertebrate inclusions in amber deposits are rare in the fossil record, known for only a few localities and time slices. Yet their 3D preservation of both hard and soft tissues offer paleontologists a detailed glimpse into the biology of extinct life that is not possible through other preservation methods. Here we will discuss a new study on a previously unreported fossil lizard specimen preserved in amber that has been housed in the collections of the Queen’s Miller Natural History museum for decades. Our goal is to establish the provenance of the sample as well the identity of the entombed lizard. Using Fourier Transform Infrared Spectroscopy (FTIR) we not only confirmed the specimen’s authenticity but have gained insight into how its spectra compares to samples from known localities to aid in confirming its source. We are employing stable isotopic analysis to further refine our knowledge of this specimen’s original location as well as the depositional environment. Finally, in conjunction with colleagues at McGill University we have CT scanned the sample and created high-resolution 3D images of the lizard, allowing us to analyze its evolutionary biology and possibly discover a new species.
13. FGF2 Gene is required for Antidepressant Treatment Effects
Authors: MacGregor Jessica
Published: April 2021

gene in humans have been shown to predict non-responsiveness to antidepressant drugs; suggesting that FGF2 is required for antidepressants to work. In this study, we hypothesized that antidepressants will not work in rodents that lack the FGF2 gene. Hence, we tested antidepressant treatment in transgenic mice that had the FGF2 gene knocked out. Chronic unpredictable stress (CUS) has been used for several decades to produce a reliable depressive and anxious phenotype in mice. This study followed a CUS paradigm and used fluoxetine (Prozac) as antidepressant treatment. Mice received daily fluoxetine administration beginning on week three of CUS and continued until the end of week five to provide an antidepressant effect and reverse the effects of stress. To test for levels of anxiety and depression, a battery of behavioral tests was conducted which began from the least stressful (i.e. sucrose preference test, open field maze, elevated plus maze) to the most stressful test (forced swim test) to prevent testing carry-over effects. AnyMaze software was used to measure behavior in the open field and elevated plus mazes by recording the amount of time each mouse spent in certain parts of the maze. Future studies will examine brain changes associated with FGF2 gene deletion – particularly in astrocyte cells – which might be necessary for successful antidepressant action. Hopefully, this will elucidate novel therapeutic targets for antidepressant and anti-anxiety medication.
THE RECONSTRUCTION OF THE CRIMINAL JUSTICE SYSTEM FOR ADDRESSING CORRUPTION CRIME IN THE FRAMEWORK OF SUPPORTING NATIONAL DEVELOPMENT
Authors: Maroni Maroni , Ariani Nenny Dwi , Putri Dheka Ermelia
Published: April 2021

The urgency for criminal justice system reconstruction of the corruption is given the legal gap in eradicating corruption law if it is only carried out by the Regional Corruption Court, which is domiciled in the Capital Province. Because the Corruption Court’s working area is so broad, it is because many corruption cases to be tried, it will also require large fees and a large number of judges, and ideally, it will take a long time in the process of examining. Meanwhile, on the other hand, there is an obligation for the corruption case settlement by the Corruption Court to be carried out quickly, simply and at low cost. This paper’s problems are: (a) Why is it important to reconstruct the Corruption Criminal Justice System? (b) What is the ideal construction of the Corruption Criminal Justice System to support national development in Indonesia? The research method is qualitative with juridical normative and sociological approaches, especially in collecting primary data to reconstruct the corruption criminal justice system.
This research shows that the ideal construction of the corruption court system is to support National Development, namely the relative competence of the Regional Corruption Court, which is not limited by the administrative area of a province. The Republic of Indonesia’s administrative area consists of various Provinces and Regencies/Cities. In these conditions, ideally, the relative competence of a Corruption Court can also examine corruption cases in districts/cities close to the Corruption Court, even though they are located in a different province from the domicile of a Corruption Court.
The Banana Leaf Approach: An Appreciation of Utilitarian Handcrafted Artifacts in the American Context
Authors: Ángel-Bravo Rafael
Published: April 2021

There is a whole wide diversity regarding how people adapt to the natural environment conditions and how they value or relate to their everyday objects and products; outside aesthetics or functionality, users appreciate utilitarian artifacts according to assorted perspectives and factors, including traditional, emotional, and cultural approaches. This paper is envisioned to propose a reflection regarding the value and significance of utilitarian handcrafted objects as a fundamental element of popular culture, associated with tradition, heritage, and folkloric preservation. Based on direct experience, photographic record, and assorted theoretical approaches, it was viable to generate a conceptual review and reflection considering the consumers’ appreciation of traditional handcrafted artifacts, understanding these implements’ value and significance beyond their form and function, as the cultural significance of handcrafted utilitarian, decorative and traditional products, as a crucial component of tangible and intangible heritages and identities in the American context.
The effect of ketamine on preventing postpartum depression
Authors: Alipoor Mina ,   Department of Anesthesiology, School of Paramedical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran, Loripoor Marzeyeh ,   Department of Reproductive Health and Midwifery, School of Nursing and Midwifery; Geriatric Care Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran,   * Corresponding Author: Marzeyeh Loripoor, PhD, Assistant Professor, Department of Reproductive Health and Midwifery, School of Nursing and Midwifery, Geriatric Care Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Fax: 009803434258497. Phone: 009809133937334. E-mail: marzeyehloripoor@yahoo.com., Kazemi Majid ,   Department of Medical Surgical Nursing, Faculty of Nursing and Midwifery, Non-Communicable Disease Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran., Farahbakhsh Farshid ,   Department of Anesthesiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran, Sarkoohi Ali ,   Department of Anesthesiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Published: April 2021

Postpartum depression is a common disabling psychosocial disorder that could have adverse effects on the life of the mother, infant, and family. The present study was conducted to evaluate the effect of ketamine on preventing postpartum depression in women undergoing caesarian sections considering the relatively known positive effect of ketamine on major depression. The present double-blind, randomized clinical trial was conducted on 134 women undergoing scheduled caesarian sections. Participants were randomly allocated into two groups of control and intervention. To induce anesthesia, 1–2 mg/kg of body weight of Nesdonal and 0.5 mg/kg of body weight of ketamine were used in the intervention group, while only 3–5 mg/kg of body weight Nesdonal was administered in the control group. Data were gathered using the Edinburgh Postnatal Depression Scale (EPDS) in three stages: before the caesarian section and two and four weeks after the caesarian section. Data were analyzed using variance analysis with repeated measures and the Chi-square test. Results of the present study showed that the mean (± standard deviation) of the depression score in the intervention and control groups were 13.78±3.87 and 13.79±4.78(p = 0.98) before the caesarian section, 11.82±3.41 and 14.34±4.29 (p < 0.001) two weeks after and 10.84±3.48 and 13.09±3.79 (p = 0.001) four weeks after the caesarian section, respectively. Using ketamine in the induction of general anesthesia could be effective in preventing postpartum depression. However, further studies are required to strengthen these findings.
Indicators of antioxidant protection of blood in necrotizing ulcerative gingivitis in experimental animals
Authors: Kilmukhametova Yuliia Hafizivna ,   Department of Therapeutic Dentistry, Higher State Educational Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine,   Department of Therapeutic Dentistry, Higher State Educational Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine,   Department of Therapeutic Dentistry, Higher State Educational Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine,   Department of Therapeutic Dentistry, Higher State Educational Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine,   Department of Therapeutic Dentistry, Higher State Educational Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine, Batig Viktor Markiyanovich , Ostafiichuk Marianna Alexandrovna , Tokar Olha Mykhaylivna , Glushchenko Tatiana Anatoliyivna ,   * Corresponding Author: Tatiana Anatoliyivna Glushchenko, Assistant Professor, Department of Therapeutic Stomatology, Bukovinian State Medical University, Ukraine. E-mail: gta89@ukr.net, Batih Iryna Viktorivna ,   Department of Pediatric Dentistry, Higher State Educational Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine, Sheremet Michael Ivanovich ,   Surgery Department No.1, Higher State Educational Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine
Published: April 2021

This article highlights the results of a study of blood parameters in animals with simulated necrotizing ulcerative gingivitis and compares them, under the same conditions, with animals that received local treatment with a developed complex of antioxidant drugs. Following the work tasks, the nature of changes in the state of the antioxidant - prooxidant system and their influence on quantitative and functional indicators of markers of inflammatory intensity was analyzed and investigated during the pathological process in the background and without treatment with a developed complex. This work shows the changes of malonic dialdehyde concentration as an indicator of lipid peroxidation intensity in experimental animals, the level of catalase activity in the blood of animals, and antioxidant-prooxidant balance in the dynamics of necrotizing ulcerative gingivitis.
Peran key opinion leader dalam pemasaran film bertema kekerasan seksual
Authors: Nurulita Fadliyya Syifa , Primadini Intan
Published: April 2021

Violence against women does not only occur in the private sphere, but also in the public sphere, for example in the workplace and educational institutions. Bombshell, a based on true story movie raises the issue of violence against women in the workplace. Promoting movies on violence against women theme in a country that still adheres to a patriarchal system is not easy. However, in Indonesia, it turned out that this movie not only attracted a large audience, but also received positive reviews from various parties. That success can be achieved due to the Marketing Public Relations strategy carried out by Cinema XXI as its distributor. This study aims to find out the Marketing Public Relations strategy of Cinema XXI in promoting Bombshell. This study is a qualitative research and data is obtained through in-depth interviews. Based on the result of this study, it is known that in order to get positive coverage, Bombshell’s marketing campaign also aimed to shape perceptions as well as to educate the audience regarding the issue of violence against women in the workplace. Furthermore, there was a significant role of Key Opinion Leaders in creating awareness about the raised issues as well as inviting audiences to watch the movie. Keywords: Bombshell  ; Key Opinion Leader; Marketing Public Relations; Violence against Women.
Atopic dermatitis – Recent advances in the management
Authors: Ramamoorthy Ramkumar
Published: April 2021

Atopic dermatitis (AD) is a chronic skin disorder resulting from complex interactions between skin barrier defects and a dysregulated immune system, marked by activation of multiple T cell subsets at different stages of the disease. Until recently, the management of AD rested mainly on the judicious use of emollients, topical steroids, and topical calcineurin inhibitors in the majority of patients and systemic immunosuppressants were advocated in severely diseased. However, in the last few years, new therapeutic strategies were designed and developed to target the various steps in the chain of molecular events that lead to the AD phenotype. This review article will focus on the recent advances in the management of AD.
High resolution ultrasound, nerve conduction study, and other non-invasive investigations in leprosy
Authors: Indu Krishnan M. U. , Sobhanakumari Kunjumani , Jose Predesh , Amitha NP , Irimpan Keerthi Joy
Published: April 2021

Leprosy is a chronic infectious condition caused by Mycobacterium leprae and is endemic in many regions of the world. The diagnosis of this condition is usually clinical except in some situations where investigations are necessary to confirm the diagnosis of leprosy or classify its clinical form. Histopathology is the usual modality for conformation of diagnosis. This review focuses mainly on high resolution ultrasound, nerve conduction study, and other non-invasive investigations in leprosy.
Pathogenesis of atopic dermatitis: Current concepts
Authors: Seneviratne Jayamini
Published: April 2021

Atopic dermatitis is the most common, yet more troublesome, inflammatory skin disease affecting mankind and its prevalence is increasing globally. In established disease, inflammation and pruritus dominate the clinical picture. Thanks to a group pioneering of dermatological scientists, we are now beginning to understand how inflammation is initiated by a primary defect in the epidermal skin barrier.
Mieszkalnictwo w Polsce w latach 2010–2018
Authors: Malesa Karolina
Published: April 2021

Artykuł porusza tematykę stanu mieszkalnictwa w Polsce w latach 2010–2018. Celem artykułu jest omówienie warunków mieszkaniowych w Polsce. Temat opisano głównie na podstawie analizy danych GUS dotyczących rynku lokali mieszkalnych w latach 2010–2018. Struktura artykułu jest następująca: po krótkim wprowadzeniu, w pierwszej części tekstu, w sposób syntetyczny, przedstawiono wielkość zasobów mieszkaniowych w Polsce. W drugiej części artykułu przeanalizowano podstawowe warunki mieszkaniowe na wojewódzkich rynkach lokali mieszkalnych w Polsce (przeciętna powierzchnia użytkowa mieszkania, przeciętna powierzchnia mieszkania przypadająca na 1 osobę, przeciętna liczba izb w mieszkaniu, przeciętna liczba osób przypadająca na 1 mieszkanie i na 1 izbę). W części trzeciej omówiono obrót na rynku lokali mieszkalnych. Czwarta część poświęcona jest roli kredytu hipotecznego w finansowaniu zakupu nieruchomości. Syntetyczna konstatacja wieńczy niniejszy tekst.

Słowa kluczowe: nieruchomość, mieszkanie, rynek nieruchomości, nieruchomości mieszkalne, ceny nieruchomości, lokale mieszkalne, warunki mieszkaniowe
PERANAN PEMERINTAH DESA DALAM PEMBANGUNAN INFRASTRUKTUR
Authors: Hariyanto Yoga
Published: April 2021

This study refers to construction in the village of Kalimas, Sungai Kakap sub-district, Kubu Raya district. The village of Kalimas covers a territory of 4565 acres with village detail (711 ha), estates (2185 ha), Talview (239), land agriculture (1370 ha) with such an area of territory, the masses of communities mostly harnessed themselves. In this study, writers use types of descriptive research with a qualitative approach. Data collection techniques with observation, interviews, and documentaries based on research conducted, it was concluded that the village government of Kalimas has managed to build infrastructures such as the construction of road, bridge, the productions of fire facilities, the post and ambulance. It will remain permanently eroded the covid-19 pandemic in Indonesia, building infrastructure in the village of Kalimas is banned because rural funds are being diverted to help stranded communities.
DAMPAK PEMBELAJARAN ONLINE PADA MATA PELAJARAN SOSIOLOGI DI MASA PANDEMI COVID-19 DI SMA 4 PANDEGLANG
Authors: Sari Siti Nita , Haryono Haryono
Published: April 2021

The Covid-19 pandemic has changed all activities around the world including the world of education due to the widespread impact of the covid-19 learning process activities in schools have been temporarily suspended and diverted to online or online learning, however, many parents have pros and cons related to online learning. Sociology learning in the midst of Covid-19 has experienced changes where there should be direct social interaction in problem-solving (face-to-face) between teachers and students turning online due to social distancing restrictions where this learning is difficult to practice for students. The purpose of this study was to determine the impact of online learning on sociology subjects at SMAN 4 Pandeglang. This research method uses qualitative methods, namely the form of interviews and observations. Based on the results of the interviews conducted, it can be seen that online learning still experiences problems such as some students do not have cellphones, unstable internet networks in remote areas, and learning media that are less supportive. In addition, students also sometimes struggle to do the assignments given by the teacher because the assignments given are too many, but students do not understand the learning material
Aktivitas Hepatoprotektor Dari Ekstrak Etanol Kerang Ale-Ale (Meretrix sp.)
Authors: Sujatmiko Bambang , Warsidah Warsidah , Prayitno Dwi Imam
Published: April 2021

Hati merupakan organ terbesar di dalam tubuh dan merupakan pusat metabolisme dan detoksifikasi senyawa kimia. Sebagai organ pusat, ternyata hati sangat rentan terhadap datangnya berbagai penyakit seperti hepatitis ataupun penyakit lainya. Penyakit hepatitis dapat terjadi karena sistem imunitas tubuh menurun sehingga virus hepatitis dengan leluasa dapat menginfeksi hati atau terbentukanya radikal bebas di dalam hati sehingga menyebabkan peradangan pada hati akibat pengaruh dari pola hidup yang tidak sehat. Konsentrasi dari radikal bebas yang tidak seimbang dengan antioksidan di dalam tubuh dapat menimbulkan stress oksidatif pada tubuh yang dapat menyebabkan kerusakan sel sehingga dapat menimbulkan penyakit degeneratif misalnya penyakit liver. Kerusakan yang disebabkan oleh radikal bebas di dalam tubuh dapat diatasi dengan antioksidan. Berdasarkan hasil penelitian yang telah dilakukan sebelumnya, diketahui bahwa ekstrak kerang ale-ale memiliki aktivitas antioksidan. Tujuan dari penelitian ini adalah untuk untuk mengetahui komponen kimia dari ekstrak kerang ale-ale (Meretrix sp.) dengan melakukan uji fitokimia dan aktivitas hepatoprotektor dari ekstrak kerang ale-ale terhadap kadar SGPT dan SGOT dari kelinci yang diinduksi dengan CCl4. Dari penelitian ini diketahui bahwa hasil pengujian fitokimia menunjukan bahwa senyawa alkaloid terkadung pada ekstrak kerang ale ale. Aktivitas hepatoprotektor dari ekstrak kerang ale-ale (Meretrix sp.) memiliki kemampuan dalam menurunkan kadar SGPT dan SGOT dari serum darah kelinci yang telah diinduksi dengan CCl4.
Struktur Komunitas Mikroalga Epifit Pada Padina dan Caulerpa di Perairan Pulau Kabung Kalimantan Barat
Authors: Hidayat Maulana , Warsidah Warsidah , Safitri Ikha
Published: April 2021

Penelitian ini bertujuan untuk mengetahui struktur komunitas mikroalga epifit pada Padina dan Caulerpa, kualitas lingkungan perairan dan korelasi kepadatan mikroalga epifit dengan parameter lingkungan perairan di Pulau Kabung Kalimantan Barat. Penelitian ini telah dilaksanakan pada bulan Oktober 2019 dengan menggunakan metode survei dan penentuan stasiun pengambilan sampel secara purposive sampling yang terdiri dari tiga stasiun berdasarkan rona lingkungan. Stasiun I terdapat dermaga kapal, stasiun II terdapat aktivitas penduduk dan stasiun III tanpa aktivitas penduduk. Struktur komunitas mikroalga epifit pada Padina dan Caulerpa di perairan Pulau Kabung terdiri dari 5 divisi, 7 kelas, 45 ordo, 62 famili dan 76 genus. Kepadatan tertinggi mikroalga epifit di Perairan Pulau Kabung terdapat di stasiun III dengan nilai (4873 ind/5g) pada Padina dan kepadatan terendah yaitu stasiun I (2653 ind/5g) pada Caulerpa. Genus yang paling mendominasi adalah Amphora, Nitzchia, Pinnularia, Synedra, Chlamydomonas dan Botrydiopsis. Kisaran indeks keanekaragaman (H') berkisar antara (3,58-3,71), indeks keseragaman (E)(0,84-0,89), indeks dominansi (C) (0,03-0,04) dan indeks similaritas Sorensen (89,70-94,28%). Parameter lingkungan perairan Pulau Kabung yang berkolerasi sempurna terhadap kepadatan mikroalga epifit adalah suhu, DO, salinitas, konduktivitas, arus dan nitrat dengan nilai 1 sampai -1, sedangkan kedalaman, fosfat dan pH cenderung tidak menunjukkan korelasi yang signifikan.
Keanekaragaman Jenis Kepiting Bakau (Scylla Sp.) Di Kuala Kota Singkawang Kalimantan Barat
Authors: Kusuma Kwirinus Rio , Safitri Ikha , Warsidah Warsidah
Published: April 2021

Hutan mangrove merupakan ekosistem pesisir yang memiliki peran penting sebagai habitat, tempat mencari makan, pemijahan, dan pembesaran berbagai jenis organisme akuatik, seperti ikan, moluska, dan crustacea, termasuk kepiting. Kepiting bakau (Scylla sp.) ditemukan melimpah di ekosistem mangrove sebagai spesies kunci. Kelimpahan kepiting bakau dipengaruhi oleh kondisi ekosistem mangrove dan kondisi lingkungan. Tujuan penelitian ini untuk mengetahui kelimpahan dan distribusi kepiting bakau serta parameter fisika-kimia lingkungan yang mempengaruhi kehidupannya. Pemilihan lokasi pengambilan sampel menggunakan metode purposive sampling berdasarkan rona lingkungan yang berbeda. Pengambilan sampel dilakukan di 3 stasiun dengan petak contoh berukuran 10x10 m dan jarak antar plot 50 m. Hasil penelitian menunjukkan bahwa kepiting bakau yang ditemukan di ekosistem mangrove Kuala Kota Singkawang Kalimantan Barat terdiri dari 2 spesies, yaitu Scylla serrata dan S. olivacea dengan kelimpahan 0,09 ind/m2 dan 0,02 ind/m2. Kepiting bakau memiliki indeks keanekaragaman rendah (0,47), keseragaman tinggi (0,68), dan dominansi sedang (0,70). Faktor fisika- kimia perairan di Kawasan mangrove Kuala Kota Singkawang masuk dalam rentang optimal yang dapat mempengaruhi keberadaan dan kelimpahan kepiting bakau.
Comparative evaluation of Skeletal, Dental, and Soft Tissue Changes in Class II Division 1 Malocclusion Cases Treated with Twin Block and innovative Clear Block Appliance - A Prospective Interventional Study
Authors: Ankita Agrawal  , Narendra Sharma  , Ranjit Kamble  , Sunita Shrivastav  , Shriya Prakash Murarka  , Akanksha Kumar
Published: April 2021

The present study was undertaken to evaluate and compare the skeletal, dental, and soft tissue changes in skeletal Class II division 1 cases treated with Twin Block and Clear Block appliances using a cephalogram. A total of 40 patients of age between 12-14 years were randomly divided into two equal groups. Group 1: treated with Twin Block appliance and Group 2: treated with Clear Block appliance. The pre-treatment lateral cephalogram was taken and skeletal, dental, and soft tissue parameters were evaluated and the appliance was delivered. After 8 months, another lateral cephalogram of all the cases was taken and analyzed. The pre and post-treatment values were compared between the two groups. The pre-treatment cases were almost comparable in skeletal, dental, and soft tissue features in both groups. There was a significant change in mandibular growth by SNB angle. The retrusion and extrusion of maxillary incisors as well as a proclination and extrusion of mandibular incisors were seen in group 1 while no change was observed in group 2. Treatment with Clear Block appliances has shown significant and favorable Skeletal, Dental and Soft tissue changes which are similar to already proven by the Twin Block appliance. Clear Block provides an esthetic and less bulky option for growth modification with similar results as compared to conventional Twin Block with the additional benefit of preventing lower incisor proclination.
Acute toxicity of jalawure (Tacca leontopetaloides (L.) Kuntze) and gadung tikus (Tacca palmata Blume) using zebrafish (Danio rerio) embryos as a model
Authors: Agus W  , Suganda A G  , Fidrianny I
Published: April 2021

Tacca is a genus of several species reported to have potential as a new therapeutic agent with toxic properties for several cells. Jalawure and gadung tikus are two species from the Tacca genus that can be found in Indonesia. The aim of this study was to determine the level of acute toxicity of jalawure and gadung tikus by using zebrafish (Danio rerio) embryos as a model. The sample was extracted by maceration using ethanol 96%. The acute toxicity test was carried out by using fish embryo acute toxicity (FET) test protocol No. 236, Organisation for Economic Co-Operation and Development (OECD), 96 hr of static exposure using the negative control group (medium embryo), the test solution group (extract) and the positive control group (3,4-dichloroaniline 4 µg/ml). The result of acute toxicity of extract against zebrafish embryos demonstrated that LC50 of jalawure leaf extract 26.06 ± 0.31 µg/ml, jalawure stem extract 251.52 ± 6.15 µg/ml,  jalawure corm extract 463.24 ± 9.68 µg/ml, gadung tikus leaf extract 15.04 ± 0.15 µg/ml, gadung tikus stem extract 263.73 ± 6.58 µg/ml, and gadung tikus corm extract 17.71 ± 0.12 µg/ml. Embryo coagulation was the endpoint that was most commonly found in almost all extracts. Gadung tikus leaves extract, gadung tikus corm extract and jalawure leaves extract expressed moderate toxicity level.
Quality of life at work of the prison agent in Ceará
Authors: Ramos Francisca  Misselângela Costa , Morais Huana Carolina Cândido , Campos Regina Kelly Guimarães Gomes , Mendes Igor Cordeiro
Published: April 2021

Objetivo: avaliar a Qualidade de Vida no Trabalho dos agentes penitenciários cearenses. Metodologia: estudo transversal e descritivo, com análise quantitativa. A coleta ocorreu nos meses de agosto e setembro de 2018, utilizando-se um questionário eletrônico com dados sociodemográficos e o instrumento Quality of Working Life Questionnaire (QWQL-Bref). A amostragem ocorreu por bola de neve e os dados foram analisados por estatística descritiva. A pesquisa foi aprovada pelo Comitê de Ética em Pesquisa do Centro Universitário Católica de Quixadá, sob parecer 2.719.401. Resultados: participaram 57 agentes penitenciários, predominando homens, com faixa etária de 31 a 43 anos de idade, casados, com ensino superior completo, que atuam na profissão de um a cinco anos, com jornada trabalhista de 40 a 48 horas semanais. A qualidade de vida no trabalho foi classificada como neutra, sendo o domínio pessoal o único com média satisfatória e o domínio profissional com menor média neutra obtida. Conclusão: a qualidade de vida no trabalho foi considerada neutra, mas os fatores de alerta para a diminuição da qualidade de vida no trabalho não podem ser subestimados. Destaca-se a importância de se promover ações para melhorar as condições de trabalho e suas implicações na saúde física e mental destes indivíduos.
Математические начала классической кардиологии
Authors: Шелестин В. А.
Published: April 2021

В монографии построен физико-математический КОНЦЕНТР-Л. Это совокупность уравнений, объединенных (как мозаика) и описывающих работу сердечно-сосудистой системы кровообращения от капилляров легких до капилляров большого круга. В работе сердце представлено как единый законченный самостоятельный функционал (в одном цикле сердце производит единую законченную физико-математическую фазу). Поэтому здесь ничего нельзя ни убавить – ни прибавить, ни пропустить – ни ошибиться, потому что тогда КОНЦЕНТР-Л не замкнется. Все положения работы выведены из классических законов физики и математики, а также показан строгий, неинвазивный способ вычисления (около 100) гемодинамических параметров сердца. Рекомендовано всем, кто хочет познать тонкие функции сердца, отказаться от первобытного «Дышите – не дышите» и начать писать «КЛАССИЧЕСКУЮ ТЕОРИЮ КАРДИОЛОГИИ».
Соціальне забезпечення незахищених верств населення: навч.-метод. посіб.
Authors: Костіна В. В.
Published: April 2021

Навчально-методичний посібник “Соціальне забезпечення незахищених верств населення» містить п’ять розділів: у першому – надано інформацію про особливості вивчення навчальної дисципліни; у другому – перелік літератури для роботи за тематичними розділами лекцій; у третьому – матеріали для підготовки до семінарських занять; у четвертому – методичні рекомендації до виконання ІНДЗ; у п’ятому – рекомендації з виконання самостійної роботи та критерії її оцінювання. У додатках – інформація для організації роботи з використанням кейс-методу. Посібник може використовуватись для підготовки здобувачів вищої освіти спеціальності «Соціальна робота», слухачів післядипломної освіти, перепідготовки та підвищення кваліфікації соціальних працівників у системі педагогічної освіти.
The Description of Lipid Profile on Injectable DMPA Contraception Acceptors in Public Health Center Banjarsengon, Jember District
Authors: Handayani Ririn , Fitrianingtyas Rizki
Published: April 2021

Injectable DMPA contraception can cause changes in lipoprotein metabolism. Changes in fat metabolism occur because of the hormonal influence of progesterone, causing disruption of the balance of lipid profiles in the body. The change in serum lipid profile (trgliseride, total cholesterol, HDL and LDL) in long-term use of DMPA is a risk factor for atherosclerosis and cardiovascular disease. The purpose of this study was to look at the description of the lipid profile at 3 months injection acceptors. The design of the study was descriptive. The population in this study was 76, the number of samples that met the inclusion and exclusion criteria in this study was 30. Examination of the lipid profile was carried out with an enzymatic colorimetric (cholesterol oxidase method / CHOD PAP). The results of lipid profile examination showed that 13.33% had high cholesterol levels, 3.33% had high triglyceride levels, 13.33% had high HDL levels, 20% had high LDL levels and 3.33% have very high LDL levels. The conclusion of this study was long term use of DMPA injection contraception could cause changes in the lipid profile, so it is recommended for acceptors who want to use contraception in the long term to use MKJP as an option so as not to affect the fat profile in the body.
Temporal and regional incidence of carbapenemase-producing Enterobacterales, Switzerland, 2013 to 2018
Authors: Ramette Alban , Gasser Michael , Nordmann Patrice , Zbinden Reinhard , Schrenzel Jacques , Perisa Damir , Kronenberg Andreas
Published: April 2021

Introduction

In contrast to countries where carbapenemase-producing Enterobacterales (CPE) are endemic, only sporadic cases were reported in Switzerland until 2013. An aggravation of the epidemiological situation in neighbouring European countries indicated the need for a surveillance study in Switzerland.

Aim

We aimed to describe CPE distributions in Switzerland and identify epidemiological factors associated with changes in incidence.

Methods

Data on all human CPE isolates from 2013 to 2018 were collected by the Swiss Centre for Antibiotic Resistance (ANRESIS) and analysed for temporal and regional trends by Generalised Poisson regression. Isolates associated with infection or colonisation were included in a primary analysis; a secondary analysis included invasive isolates only. Statistical detection of regional clusters was performed with WHONET/SaTScan.

Results

We analysed 731 CPE isolates, of which 325 (44.5%) were associated with screenings and 173 (23.7%) with infections. Yearly detection of CPE isolates increased considerably during the study period from 65 to 212. The most frequently isolated species were Klebsiella pneumoniae (54%) and Escherichia coli (28%). The most frequent genotypes were OXA-48 (43%), KPC (21%) and NDM (14%). In contrast to the French-speaking parts of Switzerland (West, Geneva) where OXA-48 were the predominant genotypes (around 60%), KPC was the most frequently detected genotype in the Italian-speaking region (63%). WHONET/SaTScan outbreak detection analysis identified seven clusters in five regions of Switzerland.

Conclusions

In a first continuous surveillance of CPE in Switzerland, we found that the epidemiological situation aggravated nationwide and that regional patterns of CPE genotypes mirrored the situation in neighbouring European countries.
Impact of January 2021 curfew measures on SARS-CoV-2 B.1.1.7 circulation in France
Authors: Di Domenico Laura , Sabbatini Chiara E , Pullano Giulia , Lévy-Bruhl Daniel , Colizza Vittoria
Published: April 2021

Following the spread of the SARS-CoV-2 B.1.1.7 variant, social distancing was strengthened in France in January 2021. Using a two-strain mathematical model calibrated on genomic surveillance, we estimated that curfew measures allowed hospitalisations to plateau by decreasing transmission of the historical strains while B.1.1.7 continued to grow. School holidays appear to have further slowed down progression in February. Without progressively strengthened social distancing, a rapid surge of hospitalisations is expected, despite the foreseen increase in vaccination rhythm.
The Importance of Depression, Anxiety and Stress on Sports Performance at Football Junior (14-16 Years)
Authors: Rozsnyai Radu Adrian , Grosu Vlad Teodor , Rusu Alina Cristina
Published: April 2021

The objective of the research: is to ascertain and show the importance of the psychological influence on the juniors in the football game. The materials and methods used in theexperiment were: motor tests: "30m straight line sprint", "Arrowhead Agility Drill" made with ball and without ball, with which we determine the motor level of the subjects and thepsychological questionnaire DASS (Depression, Anxiety and Stress), with which we evaluate the negative emotional states in the sphere of depression, anxiety and stress; The motor tests recordings were made using the "Microgate Witty System" equipment. Conclusions: The motor results obtained from the tests are influenced by the psychological level of the athletes. Depression, stress, anxiety, having an important role in reaching the potential of the athletes, their level influencing the sports performance, fact demonstrated in our study.
The Use of an Online Tennis Learning Platform for Sedentary Adults
Authors: Șerban Radu Tiberiu , Hanțiu Iacob
Published: April 2021

The purpose of this research was to analyse the impact of a web platform as a result of its use to support a leisure-time physical activity program based on the organized practice oftennis. The hypothesis of this research is based on the assumption that the use of a web platform for a recreational physical activity program, in particular a tennis one, will havebeneficial effects on the effectiveness of learning the game technique. The research was carried out on a sample of 47 volunteer subjects, all of them working in a sedentaryenvironment. The subjects of the study were divided into 3 groups, the intervention program consisted of 90-minute tennis training sessions, twice a week, for 4 months. Thestatistical analysis of the data was accomplished by using the IBM SPSS Statistics 20 program. At the end of the study, could be observed in total technical score, staticforehand, dynamic forehand, static backhand, dynamic backhand and serve score.
Relationship Between Maximum Strength and Vertical Jump Performance in Junior Speed Skaters
Authors: Ștef Raluca Doina , Grosu Emilia Florina
Published: April 2021

The aim of this study was to determine the relationships between back squat maximal strength, maximal isometric force, jump squat and countermovement jump and whether power training improves parameters mentioned above in well-trained speed skaters. Sixteen athletes devided in two groups, performed two maximal squat strength test and two vertical jump test before and after the intervention program. Absolute strength showed a strong correlation with squat jump height (r = 0.762, p < 0.001) and countermovement jump height (r = 0.760, p < 0.001) but also between maximal isometric force and squat jump (r = 0.418, p = 0.036). Percentage change within the experiment group were significantly different from pre to post intervention for each parameter tested in the order described, respectively: 14%; 16.8%; 14.9%; 9.1%. These results suggest that jump squat training can improve several athletic performances developing high levels of lower body strength to enhance jump performance.
Aprender haciendo, colaborativamente
Authors: Trejos Zelaya Ignacio
Published: April 2021

Desde el año 2000, Cenfotec ofrece disciplinas de informática con una secuencia progresiva de proyectos de integración, en los que los estudiantes aprenden a trabajar en equipos con roles y procesos definidos. El desarrollo de competencias socioemocionales está integrado en el proceso de formación.

Viajemos algunas décadas al pasado. La industria costarricense del software comenzó a tomar forma a mediados de la década de los ochenta. Diez años antes, iniciaron su formación universitaria en informática en Costa Rica. En noviembre de 1985, se eliminaron muchos impuestos a las computadoras, de modo que el 133% del impuesto al valor agregado se redujo al 10% de impuesto a las ventas.

El diseño educativo original de Cenfotec fue diseñado como una combinación de los siguientes factores: relevancia, oportunidad, integración, desarrollo humano, proceso, calidad y demanda. Las habilidades de diseño, la creatividad y la coherencia son esenciales en el trabajo de los ingenieros.