bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Equine Ocular Surface Squamous Neoplasia on Interactions between Ocular Transcriptome and Microbiome
Authors: Chow Lyndah , Flaherty Edward , Pezzanite Lynn , Williams Maggie , Dow Steven , Wotman Kathryn
Published: April 2024

Ocular surface squamous neoplasia (OSSN) represents the most common conjunctival tumor in horses and frequently results in vision loss and surgical removal of the affected globe. Multiple etiologic factors have been identified as contributing to OSSN progression, including solar radiation exposure, genetic mutations, and a lack of periocular pigmentation. Response to conventional treatments has been highly variable, though our recent work indicates that these tumors are highly responsive to local immunotherapy. In the present study, we extended our investigation of OSSN in horses to better understand how the ocular transcriptome responds to the presence of the tumor and how the ocular surface microbiome may also be altered by the presence of cancer. Therefore, we collected swabs from the ventral conjunctival fornix from 22 eyes in this study (11 with cytologically or histologically confirmed OSSN and 11 healthy eyes from the same horses) and performed RNA sequencing and 16S microbial sequencing using the same samples. Microbial 16s DNA sequencing and bulk RNA sequencing were both conducted using an Illumina-based platform. In eyes with OSSN, we observed significantly upregulated expression of genes and pathways associated with inflammation, particularly interferon. Microbial diversity was significantly reduced in conjunctival swabs from horses with OSSN. We also performed interactome analysis and found that three bacterial taxa (Actinobacillus, Helcococcus and Parvimona) had significant correlations with more than 100 upregulated genes in samples from animals with OSSN. These findings highlight the inflammatory nature of OSSN in horses and provide important new insights into how the host ocular surface interacts with certain microbial populations. These findings suggest new strategies for the management of OSSN in horses, which may entail immunotherapy in combination with ocular surface probiotics or prebiotics to help normalize ocular cell and microbe interactions.
A New Model Including AMH Cut-off Levels to Predict Post-treatment Ovarian Function in Early Breast Cancer: A Prospective Cohort Study
Authors: Omranipour Ramesh , Ahmadi-Harchegani Fatemeh , Saberi Azin , Moini Ashraf , Shiri Mostafa , Jalaeefar Amirmohsen , Arian Arvin , Seifollahi Akram , Madani Mahshad , Eslami Bita , Alipour Sadaf
Published: April 2024

Background: Breast cancer (BC) treatment decreases fertility capacity, but unnecessary fertility preservation procedures in women who would not be infertile after treatment would be a waste of time and resources and could cause the unwarranted exposure of cancer cells to exogenous sex hormones. It has been largely shown that post-treatment ovarian reserve is directly associated with pre-treatment anti-mullerian hormone levels (AMH0). A threshold for AMH0, or a model including AMH0 and patient characteristics that could distinguish the patients who will be infertile after treatments, still needs to be defined. Accordingly, this study was performed to specifically target this high-priority concern. Methods: Women≤45 years old with newly diagnosed non-metastatic BC were entered in this multicenter prospective cohort study. AMH0 and two-year post-treatment AMH (AMH2) were measured, and hormonal patient features were recorded as well. Receiver operating characteristic (ROC) curve analysis, decision tree (DT), and random forest analyses were performed to find a cut-off point for AMH0 and define a model involving related features for the prediction of AMH2. Results: The data from 84 patients were analyzed. ROC curve analysis revealed that AMH0>3 ng/mL (Area under the curve=0.69, 95% CI: 0.54‒0.84) was the best indicator for predicting AMH2≥0.7 (sensitivity=79%, specificity=60%). The best model detected by DT and random forest for predicting an AMH2>0.7 with a probability of 93% consisted of a combination of AMH0>3.3, menarche age<14, and age<31. Conclusion: This combination model can be used to withhold fertility preservation procedures in BC patients. Performing larger studies is suggested to further test this model.
Hepatoprotective Effects of Opuntia dillenii Haw Fruit in a Mice Model of Lung Cancer
Authors: Shirazinia Reza , Sadeghi Hashjin Goudarz , Muhammadnejad Ahad
Published: April 2024

Introduction: Lung cancer is an important burden, causing a massive rate of deaths every year. Using a specialized treatment regimen can improve treatment outcomes and reduce treatment-related adverse events. This study aimed to evaluate the protective effects of the Opuntia dillenii fruit hydroalcoholic extract (ODHAE) in a mouse model of lung cancer. Methods: Eight groups of lung cancer-induced BALB/c mice (each containing twelve animals) were included in this study. They were the control group, groups receiving the ODHAE extract at doses of 50, 100, and 200 mg/kg by oral gavage, the cisplatin group receiving cisplatin intraperitoneal injection, and groups receiving cisplatin and different doses of ODHAE (50, 100, and 200 mg/kg). Weight and tumor changes were evaluated in the short and long phases of the study, including 30 and 90 days, respectively. Liver transaminase and survival time were evaluated in different groups. Malondialdehyde (MDA) was evaluated in different groups as an indicator of lipid peroxidation. Statistical tests were performed using GraphPad Prism 8. Graphs were designed using GraphPad Prism 8 as well. Results: The observed weight changes were not statistically significant across all groups, except for group 8. However, in groups that did not receive cisplatin treatment, there was a significant increase in tumor volume. Conversely, tumor volume change did not reach statistical significance in all groups receiving cisplatin. The administration of ODHAE, along with cisplatin, demonstrated a dose-dependent increase in the survival time among the relevant groups. Furthermore, oral administration of ODHAE exhibited a significant reduction in transaminase levels, serving as a reliable biomarker for assessing the hepatoprotective effect of the ODHAE extract. Additionally, ODHAE displayed a dose-dependent reduction in MDA levels, indicating its potential as a therapeutic agent for mitigating oxidative stress. Conclusion: The administration of ODHAE was not effective in reducing tumor growth but significantly increased survival time and healed the liver injury induced by cisplatin.
A Review on the Role of Rodents in the Transmission of Emerging Zoonotic Bacterial Diseases
Authors: Ame Mohammedkemal Mustefa , Woyessa Mathewos Belina , Mohammed Kedir , Khan Wali , Mohamed Ziyada Farah Asma
Published: April 2024

Emerging infectious diseases (EIDs) are those that are either newly discovered in a community or those that are already there but are rapidly spreading geographically or becoming more frequent. Bacteria are considered to be the source of 54% of newly EIDs, and 175 pathogenic species are connected to diseases that are suspected of emerging. Emergent infectious diseases are those that have either not yet been identified and are impacting a population, or those that are currently present but are rapidly expanding to new regions or generating a high number of new cases within an existing population. Emerging diseases also include infectious diseases that once affected a region, declined, or were under control but are returning more frequently. Moreover, EIDs are infections that were formerly limited to a particular area, declined, or were under control but are now manifesting more frequently.
Investigating the Situation Of Infection With Respiratory System Parasitic Worms in Ethiopian Sheep
Authors: Geleto Firaol Tariku , Abdeta Tesfaye Rebuma , Regassa Motuma , Ul  Hassan Habib
Published: April 2024

Introduction: This study was conducted from October 2019 to April 2020 to determine the prevalence of lungworm infection and to assess some of the determinant risk factors associated with sheep lungworm infections in Ambo, Central Ethiopia. Methods: Fecal samples were collected from randomly selected 349 sheep, kept under extensive management systems, to examine first-stage larvae (L1) using the Baermann technique. Additionally, samples were collected from 44 sheep slaughtered in different restaurants and hotels to explore the presence of adult lungworm parasites. Results: The overall prevalence recorded from fecal and postmortem examinations was 23.2% and 31.8%, respectively. A higher prevalence was observed in females (26.2%) than in males (17.7%). Age-wise, a higher prevalence (29.1%) was observed in animals greater than six months to 2 years old, while the lowest (13.5%) was observed in animals less than or equal to 6 months. The prevalence of lungworm infection during postmortem examination of slaughtered sheep was higher (31.8%) than the result obtained at coprology (23.2%). Conclusion: This study showed that lungworm infection was a common problem among sheep in the study area. Due to its impact on production, emphasis should be given to controlling and preventing lungworm infection in the study area, such as through repeated deworming and grazing management.
Cuba - 30 Years of Innovation and Socialist Goals
Authors: Cong Tran Anh , Hiep Tran Xuan , Hung Nguyen Anh
Published: April 2024

This article studies Cuba's 30 years of innovation and socialist goals. After the Introduction and before the Conclusion, the primary content of the article is divided into three parts. The first part looks at the general situation of Cuba's reform process over the past 30 years (1993-2023). The second part identifies, analyzes and demonstrates typical factors that directly impact the pace of development and expansion of cooperation in Cuba. The third part reviews and evaluates Cuba's prospects, orientation and development potential.
IDENTIFIKASI PLANKTON DAN BENTOS DI SUNGAI TAMANROYA KECAMATAN BONTOMANAI KABUPATEN KEPULAUAN SELAYAR
Authors: Rusmidin Rusmidin , Samsi Andi Nur
Published: April 2024

Plankton dan bentos sangat penting peranannya karena dapat dijadikan sebagai bioindikator. Kelompok ini dapat menjadi indikator kesehatan lingkungan. Pengambilan sampel dilakukan di muara sungai Tamanroya di Desa Parak, Kabupaten Kepulauan Selayar pada bulan Juli 2020. Sampel plankton diambil dengan cara menyaring air dengan menggunakan plankton net. Sampel bentos diambil secara random dengan menggunakan plot ukuran 1x1 m2 pada lokasi penelitian. Analisis yang dilakukan yaitu indeks keanekaragaman, indeks keseragaman, dan indeks dominansi. Indeks keanekaragaman menunjukkan nilai stabil (H’= 2,608), indeks keseragaman menunjukkan nilai mendekati 1 (E = 0,843), dan indeks dominansi mendekati 0 (C = 0,127) pada kelompok fitoplankton. Indeks keanekaragaman menunjukkan nilai sedang (H’= 1,480), indeks keseragaman menunjukkan nilai mendekati 1 (0,920), dan indeks dominansi mendekati 0 (C = 0,253) pada kelompok zooplankton. Indeks keanekaragaman menunjukkan nilai rendah (H’= 0,283), indeks keseragaman menunjukkan nilai mendekati 1 (C = 0,905), dan indeks dominansi mendekati 0 (E = 0,283)pada kelompok bentos. Kondisi muara sungai Tamanroya tergolong belum tercemar berdasarkan indeks keanekaragaman plankton. Jika berdasarkan nilai indeks keanekaragaman bentos, maka tergolong tercemar berat.
EFEKTIVITAS KOMBINASI PUPUK ORGANIK CAIR (POC) KULIT BAWANG MERAH (Allium cepa L.), KOTORAN KAMBING, LIMBAH IKAN, DAN AIR LERI TERHADAP PERTUMBUHAN MENTIMUN (Cucumis sativus)
Authors: Rezeki Desi Tri , Jayati Ria Dwi , Harmoko Harmoko , Lestari Fitria
Published: April 2024

Penelitian ini bertujuan untuk mengetahui efektivitas pemberian kombinasi pupuk organik cair kulit bawang merah, kotoran kambing, limbah ikan dan Air cucian beras terhadap pertumbuhan dan produktivitas mentimun. jenis penelitian ini merupakan penelitian eksperimen menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan lima kali ulangan, data dianalisis menggunakan uji ANOVA dengan uji lanjutan Beda Nyata Jujur (BNJ). Dari hasil penelitian menunjukkan bahwa terdapat pengaruh yang tidak siknifikan pada pemberian kombinasi pupuk organik cair, kulit bawang merah, kotoran kambing, limbah ikan dan air cucian beras terhadap pertumbuhan mentimun
STUDI MORFOLOGI DAN FENETIK IKAN SIDAT (Anguilla sp.) DI KABUPATEN MALINAU, PROVINSI KALIMANTAN UTARA
Authors: Halimah Putri , Nursia Nursia
Published: April 2024

Penelitian ini bertujuan untuk mengetahui morfologi dan fenetik ikan sidat (Anguilla sp.) di wilayah Kabupaten Malinau sebagai potensi lokal. Lokasi penelitian di Sungai Kabupaten Malinau dengan tiga satasiun yaitu Sungai Malinau Kota, Sungai Malinau Seberang dan Sungai Taras. Metode pengumpulan data menggunakan metode penangkapan secara langsung. Identifikasi dilakukan di Kabupaten Malinau. Parameter yang diukur yaitu Morfologi dan Fenetik ikan sidat (Anguilla sp.). Adapun parameter penunjang berupa faktor lingkungan yang meliputi pH, suhu, Total Dissolve Solid (TDS) dan Dissolved oxigen (DO). Hasil dari penelitian, penulis menyimpulkan ikan sidat yang ditemukan di Kabupaten Malinau yaitu Anguilla celebenensis sebanyak 12 individu dengan karakteristik morfologi yaitu berbentuk ular berwarna gelap dengan corak kuning kecoklatan, permukaan kulit berlendir, sirip ekor meruncing, mulut berbentuk terminal, struktur gigi carniform, sirip dubur, sirip dada dan sirip punggung menyatu. Dendogram temuan sidat di Malinau yang terbentuk memiliki 1 klad dengan nilai similaritas 80%.
PENERAPAN MODEL PEMBELAJARAN GROUP INVESTIGATION BERBANTUAN DIGITAL MIND MAP (GI-DMM) TERHADAP HASIL BELAJAR SISWA RANAH AFEKTIF KELAS XI MIA SMAN 3 SOLOK
Authors: Aguspa Afifah , Maizeli Annika , Nerita Siska
Published: April 2024

Dalam proses pembelajaran belum terlaksananya pendekatan saintifik secara optimal, yang mengakibatkan kurangnya aktifitas siswa dan kurangnya pemahaman siswa terhadap materi dalam proses pembelajaran. Sehingga hasil belajar siswa masih tergolong di bawah KKM. Penelitian ini bertujuan untuk mengetahui hasil belajar siswa kelas XI MIA pada ranah afektif dengan menerapkan model pembelajaran Group Investigation berbantuan Digital Mind Map (GI-DMM) di SMAN 3 Solok. Jenis penelitian ini adalah penelitian eksperimen dengan rancangan penelitian Randomized Control Group Posttest Only Design. Populasi dalam penelitian ini semua siswa kelas XI MIA SMAN 3 Solok pada Semester Genap yang terdaftar pada Tahun Pelajaran 2022/2023 yang terdiri atas 5 kelas. Teknik pengambilan sampel menggunakan teknik purposive sampling sehingga terpilih kelas eksperimen XI MIA 5 dan kelas kontrol XI MIA 4. Hasil penelitian menunjukkan bahwa kelas eksperimen mendapatkan nilai rata-rata 86,28 sedangkan kelas kontrol mendapatkan nilai rata-rata 79,68. Hasil uji hipotesis menggunakan uji t dimana thitung 2,16 ttabel 1,67 maka H1 = diterima, artinya terdapat pengaruh terhadap ranah afektif. Berdasarkan hasil penelitian dapat disimpulkan bahwa model pembelajaran Group Investigation berbantuan Digital Mind Map (GI-DMM) berpengaruh terhadap hasil belajar siswa pada ranah afektif kelas XI MIA SMAN 3 Solok.
PERBANDINGAN EFEKTIVITAS LARUTAN KUMUR KAYU MANIS DAN MADU DENGAN OBAT KUMUR KOMERSIAL DALAM MENGHAMBAT PERTUMBUHAN Streptococcus mutans
Authors: Govanni Patricia , Budiarso Tri Yahya , Ariestanti Catarina Aprilia
Published: April 2024

Streptococcus mutans merupakan salah satu bakteri penyebab terbentuknya plak gigi. Pencegahan terbentuknya plak gigi dapat dilakukan dengan cara berkumur menggunakan obat kumur (povidone iodine, chlorexidine, propolis). Chlorexidine memiliki efek samping jika digunakan dalam jangka panjang dan povidone iodine memiliki rasa serta bau yang kurang enak. Obat kumur komersial tersebut dapat digantikan dengan larutan kumur yang berbahan alami. Kayu manis dan madu merupakan bahan alami yang memiliki sifat antibakteri dan dapat menghambat pertumbuhan S.mutans. Penelitian ini dilakukan untuk melihat perbandingan efektivitas larutan kumur kayu manis dan madu dengan produk komersial melalui uji zona hambat dan uji waktu kontak. Metode yang digunakan yaitu uji antibakteri dengan metode hole diffusion dan uji waktu kontak dengan metode total plate count (TPC) dengan variasi waktu 0, 15, 30, 45 dan 60 detik. Perbandingan komposisi larutan kumur yang digunakan yaitu 90% kayu manis dan 10% madu. Hasil uji antibakteri menunjukkan sampel memiliki diameter zona hambat (2.03 cm) yang mendekati diameter zona hambat chlorhexidine (2.43 cm). Hasil uji waktu kontak menunjukkan jumlah koloni S.mutans yang berkontak dengan larutan kumur mengalami penurunan yang efektif pada detik ke-30. Kesimpulan penelitian ini yaitu larutan kumur kayu manis dan madu memiliki efektivitas lebih kecil dari obat komersial, kecuali propolis.
La enseñanza de las artes visuales
Authors: Belardinelli Patricia Liliana , Catibiela Alejandra
Published: April 2024

El libro aborda contenidos vinculados con la enseñanza de las artes visuales y está destinado a la formación de futuros profesores que cursan las carreras de Artes Plásticas e Historia de las Artes Visuales. Centrado en la problematización de las prácticas docentes en la obligatoriedad y en la formación específica destaca la importancia del referido espacio curricular como campo de conocimiento susceptible de ser enseñado y aprendido e imprescindible para interpretar el mundo.
Lazer, Saúde e Trabalho no Contexto das Sociedades Atuais
Authors: Silva Cinthia Lopes da , Silva William Aparecido da , Rodrigues Junior Marco Aurélio
Published: April 2024

É fundamental compreendermos os problemas de saúde que cometem significativa parcela da população brasileira como Síndrome de Burnout, depressão e ansiedade. Esses problemas são decorrentes do modelo de sociedade em que se vive, do tipo de relação que se tem com o trabalho e em virtude da diminuição da realização de atividades do contexto do lazer. Assim, o presente estudo tem como objetivo analisar a produção acadêmica acerca do tema lazer, saúde e trabalho no contexto das sociedades atuais, no período de 2011 a 2022. Como procedimento metodológico foi realizada pesquisa bibliográfica de naturezas qualitativa e quantitativas. A base de dados selecionada para a busca foi o Google Acadêmico. Foram selecionados 10 artigos no intervalo de publicação de 2011 a 2022. Como resultados, as atuais características do trabalho, bem como a forma com que a sociedade tem lidado com essa atividade humana tem levado ao adoecimento da população trabalhadora, sendo que as atividades do contexto do lazer podem fazer a diferença na vida das pessoas. A pesquisa com os dados quantitativos mostrou que os principais pontos foram: 2018, 2020 e 2022 foram os anos de maior produção bibliográfica; a região sul e sudeste são majoritárias na produção do tema nos últimos 12 anos; as palavras-chave com mais repetições nos artigos foram lazer, saúde e atividades de lazer; foi predominante o número de pesquisas qualitativas e bibliográficas.
Risk Factors Analysis of Vascular Invasion in Hepatocellular Carcinoma
Authors: Faiz Belqees Yawar , Shah Sajida , Shah Inamullah , Malik Zainab , Arif Adnan
Published: April 2024

Objective: HCC carries a high recurrence rate after resection and transplant. This depends on the extent of vascular invasion. Preoperative detection of vascular invasion affects the management of patient and determines the prognosis. Vascular invasion may have to be looked for in tumors that  show certain risk factors. This study analyzes those risk factors.

Methodology: This retrospective observational study was carried out by retrieving data between 2017 to 2020. Tumors with more than 90% necrosis or those treated by chemoembolization were not included in this study. A total of 78 patients were included in the study. Multi-slice CT and 3 Tesla MRI were used as imaging tools. Vascular invasion was cross-tabulated against risk factors including size, location, morphology and encapsulation of tumor.

Results: Minimum age of patients was 22 and maximum 77 years with a mean age of 56.76 ± 10.857. Mean size of tumors was 7.29 ± 4.761 cms. Forty one patients (53%) showed vascular invasion in one or more branches of portal vein. Large tumors (p=0.002), multifocal tumors (p=0.040), unencapsulated tumors (p=0.001), infiltrative tumors (p=0.000) and those with raised serum AFP levels (p=0.016) were more likely to invade multiple vessels.

Conclusion: Larger size and multifocality of HCC are associated with more vascular invasion.

Keywords: Hepatocellular carcinoma; Vascular invasion; Imaging.
Pengaruh Celebrity Endorser Fadil Jaidi terhadap Kesadaran Merek Traffic Bun
Authors: Nugraha Muhamad Dhio , Dirgantara Pradipta
Published: April 2024

This study was conducted to determine how much influence Celebrity endorser Fadil Jaidi has on Traffic Bun Brand Awareness. The population used in this study is Fadil Jaidi's Instagram followers, and uses quantitative methods with 400 respondents who participated in filling out questionnaires through online media selected through probability sampling. The analysis techniques used are simple linear analysis and descriptive analysis. The results of this study first show that the relationship between celebrity endorsers and brand awareness has a positive effect. Second, Fadil Jaidi, as a celebrity endorser, has a 45.8% effect on brand awareness of Traffic Bun products. Meanwhile, 54.2% of the other influence is influenced by other factors that were not examined by the researcher.
Analisis Sentimen Film Dirty Vote Menggunakan BERT (Bidirectional Encoder Representations from Transformers)
Authors: Sjoraida Diah Fatma , Guna Bucky Wibawa Karya , Yudhakusuma Dudi
Published: April 2024

Penelitian ini bertujuan untuk melakukan analisis sentimen terhadap ulasan film "Dirty Vote" dari berbagai sumber, seperti media sosial, situs web ulasan film, dan forum online, dengan menggunakan model BERT yang telah di-fine-tuning. Pendekatan ini melibatkan pengumpulan data ulasan, pre-processing data, fine-tuning model BERT, dan evaluasi kinerja model. Hasil penelitian menunjukkan bahwa model BERT mencapai tingkat kinerja yang tinggi dengan akurasi, presisi, recall, dan F1-score yang melebihi ambang batas 0.8 pada dataset validasi. Analisis sentimen dari berbagai sumber mengungkapkan variasi dalam opini publik terhadap film "Dirty Vote", dengan perbedaan yang signifikan dalam sentimen yang diekspresikan melalui media sosial seperti Twitter dan Facebook dibandingkan dengan ulasan dari situs web khusus atau forum online. Selain itu, diskusi temuan analisis sentimen mengungkapkan preferensi masyarakat terhadap aspek-aspek tertentu dari film, seperti efek visual dan musik. Temuan analisis sentimen mengungkapkan bahwa efek visual dan musik mendapat penilaian tertinggi dari masyarakat, sementara pemeran dan sutradara mendapat penilaian yang lebih rendah. Informasi ini dapat digunakan oleh para pembuat film untuk memperbaiki aspek-aspek yang kurang memuaskan dalam produksi film selanjutnya.
Pengaruh Customer Relationship Management dan Kepuasan Pelanggan Terhadap Loyalitas di Cafe Pelangi
Authors: Salamena Allgreat Meidelia Clarista , Emanuel Andi Wahju Rahardjo
Published: April 2024

Penelitian ini bertujuan untuk menganalisis pengaruh penerapan Customer Relationship Management (CRM) dan kepuasan pelanggan terhadap loyalitas pelanggan di Cafe Pelangi. Dari 50 responden yang mengisi kuesioner, hasil analisis statistik menunjukkan bahwa penerapan CRM dan kepuasan pelanggan berpengaruh positif dan signifikan terhadap loyalitas pelanggan. Semua indikator variabel CRM, kepuasan pelanggan, dan loyalitas pelanggan valid dan memiliki tingkat reliabilitas tinggi. Data juga memenuhi asumsi normalitas, memungkinkan penggunaan model regresi linier berganda. Hasil regresi menunjukkan bahwa kepuasan pelanggan memiliki dampak yang signifikan pada loyalitas pelanggan, dengan koefisien determinasi sebesar 20.7%. Ini menekankan pentingnya meningkatkan kepuasan pelanggan melalui penerapan CRM untuk mencapai tingkat loyalitas yang lebih tinggi di Cafe Pelangi. Temuan ini dapat menjadi dasar strategis bagi pengelola cafe dan pemangku kepentingan lainnya untuk mengembangkan langkah-langkah yang efektif dalam mempertahankan dan memperluas pangsa pasar mereka
ARAH PEMBELAJARAN BAHASA ARAB PADA PONDOK PESANTREN DDI MANGKOSO BARRU DAN RAHMATUL ASRI MAROANGIN ENREKANG
Authors: Abdullah Abdurrahman Wahid
Published: April 2024

Traditional Islamic boarding schools are considered to teach Arabic as a tool to study classical Islamic texts (turats) for understanding their religion deeply. Whereas modern Islamic boarding schools perceive Arabic as a medium for communication, tasked with the reception and conveyance of ideas, knowledge, and information. This research took the form of field research, focusing on two research locations divided into two categories: traditional and modern. Data collection involved interviews, observations, and document analysis. Triangulation was applied in the data analysis stage. The research findings indicate that both typologies of Islamic boarding schools innovate and adapt without forsaking their distinctive characteristics, even though this might reduce the gap between them. In traditional Islamic boarding school DDI Mangkoso, the direction of Arabic language education emphasizes mastering grammar and morphology while also adopting language-oriented education. However, these schools face limitations that prevent them from achieving maximal results. On the other hand, the direction of Arabic language education in modern Islamic boarding school Rahmatul Asri focuses on mastering Arabic as a communication tool, following behaviorist theories, despite integrating nahwu-sharaf into its internal curriculum.
Modelos de evaluación del nivel de desarrollo de los destinos. Recomendaciones para el destino Cuba
Authors: Contino Rodríguez Diana , Hernández Flores Yoan , Martín Fernández Ramón
Published: April 2024

El estudio del nivel de desarrollo de los destinos, ayuda a entender la evolución de los espacios turísticos, sirviendo de base para que los gestores diseñen estrategias que permitan elevar su competitividad. Los antecedentes presentes en la web indican que en Cuba no se gestiona el sector bajo un enfoque o modelo aplicable a la realidad actual y se carece de una herramienta que permita, como parte de la planeación estratégica, evaluar el nivel alcanzado por los destinos específicos. Por ello la presente investigación tuvo como objetivo proponer las pautas para un modelo que permita la evaluación del nivel de desarrollo de los destinos turísticos cubanos. La metodología aplicada constó de dos fases que conjugan varias herramientas donde predominan las entrevistas a expertos y la revisión bibliográfica. Los principales resultados permitieron identificar que los modelos más reconocidos a nivel internacional poseen diferentes fortalezas y debilidades, su efectividad dependerá de la adaptación a las características del destino donde se aplique. La última fase de la investigación permitió proponer el Modelo Trifásico de Desarrollo más ajustado a la realidad actual del destino, aunque para su implementación deben realizarse otras investigaciones donde se realicen adecuaciones a la propuesta actual.
Análisis de la estructura de financiamiento de las Pymes del Ecuador
Authors: Gutiérrez Ponce Herenia , Espinoza Rosero Gloria Belén , Alcívar Gómez Belén Adriana Alcívar Gómez
Published: April 2024

El estudio tuvo como objetivo analizar la estructura de endeudamiento de las pequeñas y medianas empresas (Pymes) del Ecuador que forman parte del mercado bursátil para determinar si se ajusta a los supuestos de la Teoría del Orden Jerárquico, la cual defiende una jerarquía de preferencias financieras. Para procesar los datos se aplicó un modelo de regresión múltiple, que permitió explicar la variable dependiente, el endeudamiento, a través del impacto de diversas variables institucionales. Los resultados mostraron que las variables independientes edad, tangibilidad y rentabilidad se relacionan negativamente con el endeudamiento, es decir, existe una influencia de los supuestos de la Teoría del Orden Jerárquico, mientras que la variable liquidez no es estadísticamente significativa para el modelo.
Enfermedad de Chagas: Un problema de salud silente en el cantón Olmedo, provincia Manabí, Ecuador
Authors: Alejandro Polanco Carlos Regino , Rivadeneira Lucas María Alejandra , Galarza López Judith
Published: April 2024

La Enfermedad de Chagas (EC) es endémica en el Ecuador, con una notable prevalencia en la provincia de Manabí. Específicamente, el cantón Olmedo destaca como uno de los más afectados por esta enfermedad. El objetivo del presente estudio es caracterizar clínica y epidemiológicamente los casos de EC, diagnosticados desde enero 2019 a diciembre 2022 en el Cantón Olmedo, Manabí, Ecuador. Se realizó un estudio observacional, descriptivo, de registro de 14 casos confirmados por infección de Trypanosoma cruzi. Las variables estudiadas fueron, el número de casos presentados por año, sexo, grupos de edades, diagnóstico de laboratorio, tipo de vigilancia. Se identificaron un total 14 casos reactivo; mayormente representada por el sexo masculino; con predominio de personas mayores de 65 años. La vigilancia activa contribuyó al mayor número de notificaciones. El total de casos correspondieron a Chagas crónicos. Las comunidades San Roque y el barrio Divino Niño, presentaron el mayor número de notificaciones de casos confirmados. En conclusión, se plantea que la Enfermedad de Chagas representa un problema de salud silente en el Cantón Olmedo. La vigilancia activa a través de búsqueda de casos, así como los test de anticuerpos son claves en el diagnóstico.
IIST BCI Dataset-3 for 100 Malayalam Words
Authors: S Parvathy S , Sunil Nancy , Tayade Shubham , Likhitha Chittaloori , Sumitra S , Manoj B S
Published: April 2024

This paper introduces a dataset capturing brain signals generated by the recognition of 100 Malayalam words, accompanied by their English translations. The dataset encompasses recordings acquired from both vocal and sub-vocal modalities for the Malayalam vocabulary. For the English equivalents, solely vocal signals were collected. This dataset is created to help Malayalam speaking patients with neuro-degenerative diseases. This dataset not only contributes to the advancement of braincomputer interface technology but also holds promise in fostering effective communication solutions for individuals with restricted verbal abilities.
Recent Topic of Phase Angle (PhA) by Bioelectrical Impedance Analyses (BIA) Measurement for Anti-Aging Medicine
Authors: Bando Hiroshi
Published: April 2024

Anti-aging medicine has been more emphasized in developed countries. For detecting sarcopenia and frailty, bioelectrical impedance analyses (BIA) have recently attracted attention. From BIA by InBody, useful data of water balance, muscle index, and cellular health can be obtained as extracellular water/total body water (ECW/TBW), skeletal muscle mass index (SMI), and phase angle (PhA). PhA shows a close relationship with exercise habits and physical activity. The cut-off values of PhA are approximately 4.05° to 5.05°, which are related to sarcopenia. Average PhA values in males/females showed 7.7°/6.9° in university athletes and 4.1°/3.6° in aged people of 81 years old.
A STUDY ON THE IMPACT OF CRIPPLING CHINESE ECONOMY ON MULTINATIONAL CORPORATIONS: INDIA’S FDI APPROACH
Authors: Ms. S. Sruthi  , Dr. S. S. Ramya
Published: April 2024

This project explores the multifaceted impact of a crippling Chinese economy on Multinational Corporations (MNCs) and examines their strategic responses. As disruptions in China ripple through supply chains, reshaping market dynamics, and introducing regulatory ambiguities, MNCs must skillfully navigate these challenges to uphold resilience and pursue sustained growth. Concurrently, India also emerges as a potential alternative for MNCs seeking stability and growth opportunities beyond China. This research paper delves into understanding the factors of Chinas economic growth over years, the cause for the downfall, and strategic measures that India can adopt to harness the potential inflow of FDI amidst the evolving global economic landscape, such as policy reforms, infrastructure development, and sector-specific incentives. The analysis section examines the major factors that determine the economy such as GDP growth rate, Population, FDI, Youth unemployment rate, GDP Per capita income and forecast of Indias momentum in FY25 based on secondary data. The conclusion emphasizes the central theme of harnessing Indias vast growth potential while confronting the key challenges that impede its expansion. By implementing strategic policies and precise reforms, India can sustain its robust growth trajectory, surpassing the $5 trillion threshold.
KEYWORDS: Economic Landscape, Crippling Chinese economy, Indias measures, Multinational Corporations (MNCs), FDI, Sustained growth, Strategic policies, Challenges.
CONECTANDO PROFESSORES À BRINCADEIRA
Authors: Lopes Aluizio de Freitas , Arantes Sheila da Silva Ferreira , Carvalho Paulo Vitor Rodrigues de
Published: April 2024

O ato de brincar é fundamental na construção da identidade humana, moldando atributos como imaginação e sentimentos. Contudo, observa-se uma crescente desvalorização deste elemento no contexto escolar, especialmente nos anos iniciais do ensino fundamental. As exigências acadêmicas e a estruturação do tempo escolar, fortemente regida pelo relógio, limitam o espaço para atividades lúdicas espontâneas, distanciando as crianças das brincadeiras. Diante deste cenário, o presente estudo objetivou o desenvolvimento de um programa de formação continuada enriquecido com jogos e suportado pelas Tecnologias Digitais da Informação e Comunicação (TDIC). Integraram esta pesquisa-ação participativa 69 professores de Educação Física e Pedagogia, atuantes do primeiro ao quinto ano do ensino fundamental na cidade do Rio de Janeiro. Eles foram integrados em um programa de formação de dez horas, fundamentado em uma Sequência Didática (SD) que incorpora o uso das TDIC. Ao final do programa, aplicou-se um questionário baseado na escala Likert, cujas respostas foram coletadas anonimamente para análise. Os resultados mostraram que, embora a maioria dos participantes admitam a utilização de recursos digitais em suas aulas, a apropriação destes mesmos recursos para promover atividades lúdicas com os docentes ainda é encarada com ineditismo. Ainda segundo as respostas dos participantes, a formação oferecida foi capaz de fazê-los repensar suas estratégias de ensino. Por fim, é possível destacar o potencial motivador das TDIC e seu sucesso em proporcionar novas experiências lúdicas.
Comprehensive evaluation of efficiency to identify deficiencies in muscle activity in different modes in team sports
Authors: Tyshchenko Valeria , Tyshchenko Denys , Andronov Vitalii , Ivanenko Stanislav , Adamchuk Vadym , Hlukhov Ivan , Drobot Katerina
Published: April 2024

Aim: To concern the scientific substantiation of a complex ergometer tests of aerobic and anaerobic character and quantitative criteria for assessing the condition of female handball players` respiratory and power supply systems in the maximum.
Materials and Methods: Descriptive analysis, correlation analysis, factor analysis. In order to solve those tasks within the framework there were measured the indicators of two hundred young female handball players at the pre-basic training stage.
Results: The outcomes of the research allow us to recommend the program for handball players` potential capabilities assessment that will help to characterize the state of power supply systems of the body under aerobic and anaerobic conditions. At the same time, the results of the testing can be used to identify strengths and weaknesses in the structure of handball players` special readiness indicators and to individualize the process of players’ preparation at the subsequent stages.
Conclusions: As a result of experimental data, the quantitative criteria and the scale for the assessment of handball players’ working capacity in ergometer maximum tests of aerobic-anaerobic character have been developed. On the basis of these tests, it is possible to analyze objectively the individual characteristics of children before making a final decision.
Analysis of cases of premature rupture of membranes and preterm births to identify effective management measures to prevent them
Authors: Skrypchenko Nataliia Y. , Lozova Liliia A.
Published: April 2024

Aim: Based on retrospective analysis recognize the key factors of development of premature childbirth and elaborate highly specific criteria for individual prognosis to improve perinatal outcomes.
Materials and Methods: A retrospective analysis of the birth histories of 250 women and their newborns with spontaneous preterm births at 22-36 weeks was conducted using archival data from the department for pregnant women with obstetric pathology of the State Institution “Institute of Pediatrics, Obstetrics and Gynecology named by academician OM Lukianova of the National Academy of Medical Sciences of Ukraine”
Results: Important risk factors for premature rupture of membranes (PROM) in preterm pregnancy include the presence of sexually transmitted diseases (χ2=31.188, p=0.001), bacterial vaginosis (χ2=30.913, p=0.0001), a history of abortion and/or preterm birth (χ2=16.62, p=0.0002), SARS during pregnancy (χ2=16.444, p=0.0002), chronic adnexitis in anamnesis (χ2=11.522, p=0.0031), inflammatory cervical disease (χ2=11.437, p=0.0032), anaemia (χ2=10.815, p=0.0044), isthmic-cervical insufficiency (ІСІ) (χ2=10.345, p=0.0057), chronic pyelonephritis with exacerbation (χ2=9.16, p=0.01), smoking during pregnancy (χ2=10.815, p=0.0044).
Conclusions: The results of a retrospective analysis of 250 cases of preterm birth at 22 to 36 weeks allowed us to identify ways to effectively use existing diagnostic measures to determine readiness for pregnancy and the possibility of prolonging pregnancy to the viability of the newborn. Ways to improve the prevention of preterm birth and the design of further research were identified.
Structure and features of psychopathological symptoms in forced migrants and internally displaced persons
Authors: Venger Olena , Mysula Yuriy , Oliynyk Oleksandr , Striepetova Olena , Kulivets Oleksii
Published: April 2024

Aim: To study the structure and characteristics of psychopathological symptoms in FM who left Ukraine as a result of the full-scale armed aggression of the Russian Federation against Ukraine, and internally displaced persons, in a comparative aspect.
Materials and Methods: Examination was performed in compliance with the principles of biomedical ethics, based on informed consent. Research was provided on the basis of the Ternopil Regional Clinical Psychoneurological Hospital. Inclusion criteria were women who were forced to leave the territory of Ukraine as a result of hostilities after February 24, 2022, and who left for temporary residence in the territory of the Republic of Poland (Poland) (FM), and women who were temporarily relocated within Ukraine in connection with connection with hostilities (IDP). Exclusion criteria from the study were presence of language disorders, pronounced cognitive disorders, severe somatic condition. The examination was organized by the method of a semi-structured clinical interview according to the developed by us protocol and was conducted remotely. During the examination, depressive, anxiety-phobic, asthenic and dyssomnic disorders, addictive behavior and symptoms of PTSDwere identified and verified. Statistical and mathematical processing a was carried out using Fisher’s exact test.
Results: The data we obtained indicate a significant spread of psychopathological symptoms in FM and IDP.
Conclusions: FM and IDP are characterized by a high incidence of psychopathological symptoms. The most frequent were: depressed mood (FM – 67.2%, IDP – 58.5%), feelings of anxiety and fear (FM –52.5%, IDP – 43.6%), obsessive thoughts (FM – 58.9 %, IDP – 49.5%).
Comorbid pathology of the mammary glands and endometriosis: risk factors and prognosis
Authors: Boychuk Alla V. , Miklashevska Olena A. , Khlibovska Oksana I. , Yakymchuk Yuliia B. , Nikitina Iryna M. , Herevych Nadiia V.
Published: April 2024

Aim: based on a retrospective analysis, the relationship between external genital endometriosis and comorbid breast pathology was established and risk factors were identified, their comparison and the formation of a prognostic risk criterion were determined.
Materials and Methods: to address the objectives of the study, a retrospective analysis of 470 cases of patients treated for external genital endometriosis after surgical treatment and comorbid breast pathology was conducted. The control group included 30 healthy non-pregnant women. Statistical processing was performed on a personal computer using the statistical software package Statistica 10.
Results: As a result of the analysis, the age of the patients ranged from 23 to 40 years. The average age of patients in the study group was (32.2}1.18) years, and in the control group (31.1}1.35) (p>0.05). The groups were homogeneous in terms of age (p>0.05), marital status (p>0.05) and level of education (p>0.05). Close relatives in 208 (44.25}2.18) % (OR=8.86; 95 % CI: (0.68-10.53); p<0.002) cases suffered from benign (hormone-dependent) tumours and tumour-like diseases of the uterus and appendages in isolation or in various combinations (fibroids, adenomyosis, endometrial hyperplasia). It was also found that 102 (21.70}1.67) % of patients had endometriosis, which may indicate a genetic predisposition to this disease. In the closest relatives of EM patients: in 118 (25.10}2.01) % of the examined parents, breast problems were noted, in 66 (14.04}1.12) % – diabetes mellitus, and in 98 (20.85}1.22) % thyroid diseases were detected, which in total amounted to (60.00}2.23) % (OR=9.12; 95 % CI: (0.58-11.54); p<0.002). Early menarche almost tripled the risk of EM (OR=2.72; 95% CI: (1.02-5.11); p<0.002), and menstrual irregularities doubled it (OR=2.04; 95% CI: (1.09-3.14); p<0.05), higher education, urban residents – 2.2 times higher (OR= 2.27; 95 % CI: (1.11-3.63); p<0.05), diseases of the gastrointestinal tract and hepatobiliary complex – 5.2 times higher (OR=5.27; 95 % CI: (1.89-12.03); p<0.05), frequently recurrent inflammatory diseases of the appendages – 3 times higher (OR=3.14; 95 % CI: (0.91-5.14); p<0.05), dysmetabolic manifestations (thyroid dysfunction) – 5 times higher (OR=5.11; 95 % CI: (1.61-9.503); p<0.002).
Conclusions: Thus, in endometriosis and dyshormonal diseases of the mammary glands, menstrual and generative function disorders, along with clinical symptoms of pelvic pain, dysmenorrhoea, autonomic nervous system disorders and sexual dysfunction, are significant components of this problem, initiating comorbidity processes in target organs in the setting of hormonal maladaptation. Therefore, these comorbidities become a trigger for the activation of systemic hormonal imbalance and become an urgent interdisciplinary problem that requires further study.
Possibilities of predicting adverse cardiovascular events based on the analysis of clinical and instrumental research methods, as well as sST2 in patients after myocardial infarction
Authors: Volynskyi Denys A. , Vakaliuk Ihor P. , Tymochko Nataliia B. , Zvonar Pavlo P.
Published: April 2024

Aim: To determine the possibility of predicting adverse cardiovascular events based on the analysis of clinical and instrumental research methods, as well as sST2 in patients after myocardial infarction.
Materials and Methods: The study included 64 patients who suffered an acute myocardial infarction and underwent PCI with balloon angioplasty and stenting of the infarct-related vessel in the acute period. The predictors of adverse cardiovascular events were assessed events during 1 year of observation. Indicators of echocardiography and coronary angiography were assessed and concentrations sST2.
Results: A worse prognosis was associated with intermediate ejection fraction (EF) (odds ratio (OR)=3.981, p<0.05), left aneurysm ventricle (LV) (OR=29.5, p<0.05), high concentrations of sST2 (OR=1.017, p<0.05) and scores on the Syntax scale (OR=1.001, p<0.05).
Conclusions: In patients who underwent percutaneous coronary intervention for myocardial infarction, adverse outcome during the next 2 years is associated with coronary and echocardiographic parameters, as well as biochemical indicators of myocardial stress and fibrosis. HF patients with intermediate EF, LV aneurysm, high sST2 concentrations, and high Syntax scores have the worst prognosis.
Atypical course of incarcerated post-traumatic diaphragmatic hernia
Authors: Kryzhanovskyi Olexandr , Dolzhkovyi Serhii , Sheiko Volodymyr , Zhamardiy Valery
Published: April 2024

The article focuses on the instrumental imaging methods which greatly enhance the possibilities when arriving at correct and quick diagnosis of acute surgical pathology. Analysis of clinical and anamnestic data of the disease course and the results of instrumental research methods made it possible to arrive at clear clinical diagnosis, determine the indications for surgical treatment in this specific clinical case. The use of modern visualization methods while examining the patients prevents errors in diagnosis and helps to determine the optimal treatment tactics.
Komicy i komiksy. Drugie życie gwiazd kina międzywojennego
Authors: Świdziński Wojciech
Published: April 2024

W komiksach publikowanych w polskiej prasie dwudziestolecia międzywojennego wyraźny nurt stanowiły humorystyczne historyjki o filmowych komikach. W artykule są omawiane „filmy rysunkowe” (jak wówczas nazywano prasowe komiksy) poświęcone Charliemu Chaplinowi, Patowi i Patachonowi, oraz komiksowe wcielenia gwiazd kina i kabaretu – Kazimierza „Lopka” Krukowskiego i Adolfa „Dodka” Dymszy. Większość tych utworów podkreśla sowizdrzalskie rysy ekranowych komików, co zwłaszcza w przypadku Chaplina stanowiło powrót do jego filmowych początków. W niektórych z komiksów można dopatrzyć się też reminiscencji konkretnych filmów, jak również – zwłaszcza w przypadku Dodka – próby adaptacji specyficznego języka postaci. Trudno określić, na ile owo drugie życie gwiazd ekranu na łamach prasy komponowało się z odbiorem ich filmów. Z pewnością jednak potęgowało popularność, minimalizując bariery między idolami kina a publicznością, która w wyobraźni przenosiła ich przygody w swojskie realia.
O intermedialnych relacjach między filmem i grami wideo
Authors: Zawojski Piotr
Published: April 2024

Książka Joanny Pigulak Gra w film. Z zagadnień relacji między filmem i grami wideo (2022) to interdyscyplinarne studium dotyczące relacji zachodzących pomiędzy filmem i grami wideo. Autorka skupia się przede wszystkim na analizie filmowych środków wyrazu wykorzystywanych w grach, a także opisuje i interpretuje ich funkcjonowanie w medium interaktywnym, jakim są gry wideo. Korzysta przy tym z zaplecza teoretycznego oraz metod analitycznych wypracowanych na gruncie zarówno filmoznawstwa, jak i groznawstwa, co wpisuje się w model medioznawstwa zorientowanego kulturoznawczo. Na uwagę zasługują analizy i interpretacje filmów i gier powstałych po 2003 r., czyli po upowszechnieniu się konsol siódmej i ósmej generacji. Refleksjom tym towarzyszy namysł teoretyczny, odwołujący się do kluczowych kategorii wiedzy o mediach audiowizualnych, takich jak remediacja, konwergencja, inter- i transmedialność, immersja, a także prezentacja zagadnień szczegółowych: point of view, mise-en-scène, kadrowanie czy narracje transmedialne.
O trzech tendencjach kina pamięci narodowej
Authors: Durys Elżbieta
Published: April 2024

Autorka podejmuje namysł nad współczesnymi polskimi filmami historycznymi (kino pamięci narodowej) i umieszcza je w perspektywie badań nad pamięcią. Wykorzystując kategorię nostalgii w ujęciu Svetlany Boym (2001), wraz z jej rozróżnieniem na nostalgię restauratywną i nostalgię refleksyjną, oraz posiłkując się odwołaniami do formuł gatunkowych (trybu melodramatycznego oraz kina kryminalnego), wyodrębnia trzy tendencje w przedstawianiu przeszłości w kinie pamięci narodowej. Dla ich oznaczenia proponuje określenia: tendencja heroizacyjna, tendencja spiskowego porządkowania świata oraz tendencja przeszłości w barwach ORWO. Odwołując się do przykładów, wskazuje stosowane w omówionych tendencjach mechanizmy oraz zestawy praktyk dyskursywno-pamięciowych.