bluuebunny/crossref_metadata_2025 huggingface dataset:
Length of stay in a behavior change program in Primary Health Care: “VAMOS” Program
Authors: Konrad Lisandra Maria , Tomicki Camila , Ribeiro Cezar Grontowski , Bezerra Juciléia Barbosa , Maciel Elaine Cristina , Rech Cassiano Ricardo , Pitanga Francisco José Gondim , Benedetti Tânia Rosane Bertoldo
Published: December 2019

The present study aims to analyze the length of stay of adults and elderly individuals in the “Vida Ativa Melhorando a Saúde” (VAMOS - Active Life Improving Health) program implemented in Primary Health Care (PHC) in Brazil. A total of 106 users (87.7% females) aged 55.42 years (± 12.22) were followed during 12 weeks in four Community Health Centers. Length of stay was analyzed according to socio-demographic variables (sex, age, marital status, level of education, current occupation, family income) and the indicators of VAMOS program effectiveness (physical activity level and food intake). Descriptive statistics, chi-square test, survival analysis applied by the Kaplan-Meier method and multivariate COX regression model were used. A significance level of 5% was adopted in all analyses. The rate of length of stay was 51.9% (n = 55). Marital status was associated with a longer length of stay (p < 0.05). Furthermore, having a partner (OR = 2.11; 95%CI: 1.16 - 3.81) was associated with a longer length of stay in the program. In conclusion, more than half of the adults and elderly individuals remained in the VAMOS Program and length of stay was greater among those with a partner.
Critical Condition: People Don’t Dislike a Corporate Experiment More Than They Dislike Its Worst Condition
Authors: Mislavsky Robert , Dietvorst Berkeley , Simonsohn Uri
Published: December 2019

Recent public backlash to corporate experimentation was likely caused by the policies the experiments contained rather than a more general “experiment aversion.”
Impurities and Homogeneous Crystal Nucleation in Aqueous Solutions - An Overview
Authors: Mahadevan C. K.
Published: December 2019

Nucleation process is the most important stage in the formation of a crystal and has attracted the attention of researchers due to its importance in many technological and biological contexts. As the presence of impurities affects the nucleation process significantly, several studies have been made in the past to understand it. In this article is presented an overview of various studies made to understand the effect of soluble impurities on the crystal nucleation parameters of certain important materials in aqueous solution focusing the results reported by the research group of the present author.
Synthesis, Characterization and Methyl Orange Degradation Activity of Ti-Al Oxides Nanomaterial
Authors: Abebe Buzuayehu , Murthy H C Ananda
Published: December 2019

The present work reports the synthesis of Ti-Al Oxides (TAOs) nanomaterial by an organic solvent-free impregnation method. The as-prepared products were studied by XRD, SEM-EDAX, UV-Vis, and FT-IR analytical techniques. XRD patterns revealed the fact that both TiO2 (TO)and TAOs exhibited almost similar peaks with the exception to minor peak difference in width and height which could be attributed to the alteration in the size of particles. At the calcination temperature of 500 oC, the absence of peaks for Al2O3 (AO) in the TAOs XRD pattern indicates the amorphous nature of AO. However, the appearance of Ti, Al, and O on EDAX and redshift on UV-Vis spectra confirm the successful impregnation of AO on TO. The pollutant degradation ability of TAOs photocatalyst was tested on methyl orange (MO) dye. Compared to pure TO, TAO composite has greater degradation efficiency. However, as the percentage of AO increases the degradation efficiency decreases. The conducted Langmuir model test was found to fit well for the photocatalytic reaction process following first-order reaction kinetics. Comparing the values for kinetics constant with earlier work, this work showed good MO degradation efficiency with reaction rate constant (k) values of 0.023.
Hydro-Oceanographic and Water Quality Assesments As a Basis for the Development of Offshore Aquaculture in the Weh Island, Aceh Province, Indonesia
Authors: Ondara Koko , Altanto Try , Rahmawan Guntur Adhi , Dhiauddin Ruzana , Wisha Ulung Jantama , Ridwan Nia Naelul Hasanah
Published: December 2019

The waters of Weh Island, Aceh Province has potency become the area for offshore aquaculture. Offshore Floating Net Cages can be an appropriate technology in increasing the biomass cultivation in Weh Island waters. However, no feasibility study has been done.  Therefore, this study aims to examine the suitability of offshore aquaculture locations in the East and South regions of Weh Island Based on Hydro-oceanography parameters. The parameters examined were water quality parameters such as temperature, brightness, pH, salinity and dissolved oxygen. In addition, we also examined the aspects of physical oceanography such as tides, currents and bathymetry. The results show that the water depth ranged from 0-57 m. The tidal type in the Weh Island waters is mixed tide prevailing semidiurnal with the tidal range of 1.9 m. The average of current speed ranged from 19.03-37.67 cm/s with the directions predominantly toward northwest and southeast.  It is concluded that the water quality data show that the eastern and southern parts of Weh Island are categorized as the feasible locations for offshore aquaculture.  Keywords: Sabang, Hydro-oceanography, Fisheries, Offshoreaquaculture, Floating net cages
Sub-activity Time-Cost Trade-off Model of Building Structural Beam on the Projects in the North Aceh Region
Authors: Fachrurrazi Fachrurrazi , Abdullah Abdullah , Away Yuwaldi , Aulia Teuku Budi
Published: December 2019

Problems for both delayed and accelerated activities in scheduling are common in most projects. This problem can implicate on the additional construction cost with different trends as a specific model. A model can provide valuable information to project acceleration judgement. This research aims to develop the TCTO sub-activity model of formwork, rebar work, and concrete work of the building structural beam on the projects in the North Aceh region. We have collected 33 data sourced from the project cost plan report and respondents judgment in the reviewed area. Descriptive statistics and the regression analysis are used to generate the TCTO model. The results show that the activity duration of the structural beam as broken down into sub-activities of formwork, rebar work and concrete work can be compressed until reaching 40%, 50%, and 40% of its normal duration, respectively. The additional cost of the compressed duration for each sub-activity shows the direct incremental cost per days of 3.67%, 3.63%, and 4.27% of its normal cost. Meanwhile, the possible crash cost of each the sub-activities are 122%, 118.15%, 125.61%, respectively. The models practically represent a linear model in the same daily pattern acceleration.
The Significance Risk for Factors of Labour, Material, and Equipment on Construction Project Quality
Authors: Husin Saiful , Mubarak Mubarak , Fachrurrazi Fachrurrazi
Published: December 2019

The construction involves a series of activities that possibly face problems or risks. The risk probability is an uncertain condition that results in a negative impact on the project objectives. Threats can come from the resources factor in a construction project, such as labour, materials, and equipment. The handling of risks in construction work needs to be further reviewed. It is to find risk factors and risk variables contributing to high risk to achieve the quality objectives of construction implementation. The purpose of this study was to analyze the most significant risk towards the quality of construction associated with the condition of the Province of Aceh during 2000-2015. The situation is classified in three periods, namely political conflict (2000-2004 as Period I), rehabilitation and reconstruction (2005-2009 as Period II), and post-rehabilitation and reconstruction (2010-2015 as Period III). Dataset is collected using questionnaires to 15 large qualified contractor companies to capture construction quality information. The risk significance identified based on Risk Importance Index (RII) for frequency and severity of factors and variables. There are 7 variables for labour resources, 10 variables for material resources, and 17 variables for equipment resources. The quality of construction mostly affected by the labour resources factors in Period I and Period III. The risk comes from the variable discipline of workers who are not good (A3). For Period II, the lack of labour capacity (A2) variable become as the most significant risk.
Discrimination of hazardous bacteria with combination laser-induced breakdown spectroscopy and statistical methods
Authors: Zhao Yu , Wang Qianqian , Cui Xutai , Teng Geer , Wei Kai , Liu Haida
Published: December 2019

Real-time biohazard detectors must be developed to facilitate the rapid implementation of appropriate protective measures against foodborne pathogens. Laser-induced breakdown spectroscopy (LIBS) is a promising technique for the real-time detection of hazardous bacteria (HB) in the field. However, distinguishing among various HBs that exhibit similar C, N, O, H, or trace metal atomic emissions complicates HB detection by LIBS. This paper proposes the use of LIBS and chemometric tools to discriminate Staphylococcus aureus, Bacillus cereus, and Escherichia coli on slide substrates. Principal component analysis (PCA) and the genetic algorithm (GA) were used to select features and reduce the size of spectral data. Several models based on the artificial neural network (ANN) and the support vector machine (SVM) were built using the feature lines as input data. The proposed PCA-GA-ANN and PCA-GA-SVM discrimination approaches exhibited correct classification rates of 97.5% and 100%, respectively.
Geometric calibration method based on a two-dimensional turntable for a directional polarimetric camera
Authors: Huang Chan , Meng Binghuan , Chang Yuyang , Chen Feinan , Zhang Miaomiao , Han Lin , Xiang Guangfeng , Tu Bihai , Hong Jin
Published: December 2019

The directional polarimetric camera (DPC) is a polarization sensor with ultra-wide-angle and low-distortion imaging characteristics. Geometric calibration is usually the first essential step before remote sensing satellites are launched. In this paper, a geometric calibration method based on a two-dimensional turntable and a rotation matrix with high precision, simple operation, and wide application range is proposed for the directional polarimetric camera. Instead of precisely adjusting the position of the sensor on the turntable, the method effectively eliminates the errors caused by the mechanical axis of the turntable and the optical axis of the sensor not being adjusted to the same direction through the rotation transformation of the coordinate system. The geometric calibration experiments of the directional polarimetric camera were carried out with the method of Chen et al. [Optik 121, 486 (2010)10.1016/j.ijleo.2008.08.004OTIKAJ0030-4026] and the proposed method. The experimental results showed the calibration residual of the proposed method was less than 0.1 pixel while Chen’s method was 0.3 pixel. The mean reprojection error and root mean square error of the proposed method were reduced to 0.06352 pixel and 0.06961 pixel, respectively. The geometric calibration parameters obtained by the proposed method were used for geometric correction of the in-orbit images of the DPC, and the results also prove the effectiveness and superiority of the proposed method.
The Verriest Lecture: Adventures in blue and yellow
Authors: Webster Michael A.
Published: December 2019

Conventional models of color vision assume that blue and yellow (along with red and green) are the fundamental building blocks of color appearance, yet how these hues are represented in the brain and whether and why they might be special are questions that remain shrouded in mystery. Many studies have explored the visual encoding of color categories, from the statistics of the environment to neural processing to perceptual experience. Blue and yellow are tied to salient features of the natural color world, and these features have likely shaped several important aspects of color vision. However, it remains less certain that these dimensions are encoded as primary or “unique” in the visual representation of color. There are also striking differences between blue and yellow percepts that may reflect high-level inferences about the world, specifically about the colors of light and surfaces. Moreover, while the stimuli labeled as blue or yellow or other basic categories show a remarkable degree of constancy within the observer, they all vary independently of one another across observers. This pattern of variation again suggests that blue and yellow and red and green are not a primary or unitary dimension of color appearance, and instead suggests a representation in which different hues reflect qualitatively different categories rather than quantitative differences within an underlying low-dimensional “color space.”
Segmented Bayesian optimization of meta-gratings for sub-wavelength light focusing
Authors: Zhang Dasen , Qin Feifei , Zhang Qiang , Liu Zhenzhen , Wei Guochao , Xiao Jun Jun
Published: December 2019

Using inverse design tools to engineer functional photonic nanostructures has been a subject of great interest over the past several years. We report combining a segmented Bayesian optimization algorithm with the rigorous coupled wave analysis to design meta-gratings for sub-wavelength light focusing. Specifically, the meta-gratings comprise one-dimensional periodic arrays of supercells, each of which consists of dozens of dielectric bars. By optimizing geometry of the structure, we demonstrate two kinds of meta-gratings operating at single and double wavelengths, respectively. Both of them can focus the incoming light into periodic sub-wavelength spots with high energy density. The full width at half-maximum (FWHM) of the focusing spots for the single wavelength (

λ
=
633

n
m

) case can be as small as

0.36
λ

, while FWHMs of the focusing spots at double wavelengths (

λ
=
533

n
m

and 633 nm) are about

0.4
λ

. This proposed approach provides an affordable method to tackle the problem of complex photonic structure design.
Statistically driven model for efficient analysis of few-photon transport in waveguide quantum electrodynamics
Authors: Cui Ruiqi , Tan Dian , Shen Yuecheng
Published: December 2019

Understanding transport properties in quantum nanophotonics plays a central role in designing few-photon devices, yet it suffers from a longstanding extensive computational burden. In this work, we propose a statistically driven model with a tremendously eased computational burden, which is based on the deep understanding of the few-photon spontaneous emission process. By utilizing phenomenological, statistically driven inter-photon offset parameters, the proposed model expedites the transport calculation with a three-order-of-magnitude enhancement of speed in contrast to conventional numerical approaches. We showcase the two-photon transport computation benchmarked by the rigorous analytical approach. Our work provides an efficient tool for designing few-photon nano-devices, and it significantly deepens the understanding of correlated quantum many-body physics.
Single frontal projection autostereoscopic three-dimensional display using a liquid crystal lens array
Authors: Wang Zi , Xu Miao , Lv Guoqiang , Feng Qibin , Wang Anting , Ming Hai
Published: December 2019

Frontal projection autostereoscopic three-dimensional (3D) display is a kind of excellent 3D display technique with large display size and efficient space utilization, especially suitable for the future glasses-free 3D cinema. In this paper, we propose a frontal projection autostereoscopic 3D display using a liquid crystal lens array (LCLA) and a quarter-wave retarding film. The LCLA acts as two roles, refraction and transparency, for different polarized light. The forward projected polarized light can pass through the LCLA as a transparency, and then pass through the quarter-wave retarding film. After reflecting from a polarization-preserving screen, the returned light will pass through the quarter-wave retarding film again and turn to an orthogonal polarization. This polarized light will be refracted by the LCLA and reconstruct the 3D image. The demonstrated LCLA has the merits of no driving voltage, simple fabrication, and cost-effective. Optical experiment verifies the proposed method, which is promising for its potential application in the future glasses-free 3D cinema.
Self-assembly plasmonic metamaterials based on templated annealing for advanced biosensing
Authors: Li Lixia , Liang Yuzhang , Zong Xueyang , Liu Yufang
Published: December 2019

In this paper, we introduce a novel method for the fabrication of self-assembly plasmonic metamaterials by exploiting fluid instabilities of optical thin films. Due to interplay between template reflow and spinodal dewetting, two metal nanoparticles of different sizes are generated on the top mesas of free-standing porous anodic aluminum oxide (AAO) template, which results in the apprearance of double resonant peaks in the extinction spectrum. These two resonant peaks possess refractive index resolution 3.27 × 10−4 and 2.53 × 10−4 RIU, respectively. This optical intensity modulation based plasmonic nanoplatform shows a dramatically surface sensing performance with outstanding detection capacity of biomolecules, because of the very small decay length of electric field at dual-modes. The detection ability for concanavalin A (Con A) demonstrats that the limit of detection of dual-modes reaches as small as 68 and 79 nM, respectively.
Speckle reducing OCT using optical chopper
Authors: Li Rui , Yin He , Hong Jiaying , Wang Chengming , He Bin , Chen Zhengyu , Li Qin , Xue Ping , Zhang Xiao
Published: December 2019

Optical coherence tomography (OCT) has been an important and powerful tool for biological research and clinical applications. However, speckle noise significantly degrades the image quality of OCT and has a negative impact on the clinical diagnosis accuracy. In this paper, we propose a novel speckle noise suppression technique which changes the spatial distribution of sample beam using a special optical chopper. Then a series of OCT images with uncorrelated speckle patterns could be captured and compounded to improve the image quality without degradation of resolution. Typical signal-to-noise ratio improvement of ∼6.4 dB is experimentally achieved in tissue phantom imaging with average number n = 100. Furthermore, compared with conventional OCT, the proposed technique is demonstrated to view finer and clearer biological structures in human skin in vivo, such as sweat glands and blood vessels. The advantages of low cost, simple structure and compact integration will benefit the future design of handheld or endoscopic probe for biomedical imaging in research and clinical applications.
Ultra-narrowband polarization insensitive transmission filter using a coupled dielectric-metal metasurface
Authors: Nagarajan A. , van Erve K. , Gerini G.
Published: December 2019

A coupled dielectric-metal metasurface (CDMM) filter consisting of amorphous silicon (a-Si) rings and subwavelength holes in Au layer separated by a SiO2 layer is presented. The design parameters of the CDMM filter is numerically optimized to have a polarization independent peak transmittance of 0.55 at 1540 nm with a Full Width at Half Maximum (FWHM) of 10 nm. The filter also has a 100 nm quiet zone with ∼10−2 transmittance. A radiating two-oscillator model reveals the fundamental resonances in the filter which interfere to produce the electromagnetically induced transparency (EIT) like effect. Multipole expansion of the currents in the structure validates the fundamental resonances predicted by the two-oscillator model. The presented CDMM filter is robust to artifacts in device fabrication and has performances comparable to a conventional Fabry-Pérot filter. However, it is easier to be integrated in image sensors as the transmittance peak can be tuned by only changing the periodicity resulting in a planar structure with a fixed height.
Fast and direct measurement of the linear birefringence profile in standard single-mode optical fibers
Authors: Costa Luis , Magalhães Regina , Palmieri Luca , Martins Hugo , Martin-Lopez Sonia , Fernández-Ruiz María R. , Gonzalez-Herraez Miguel
Published: December 2019

Phase birefringence in optical fibers typically fluctuates over their length due to geometrical imperfections induced from the drawing process or during installation. Currently commercially available fibers exhibit remarkably low birefringence, prompting a high standard for characterization methods. In this work, we detail a method that uses chirped-pulse phase-sensitive optical time-domain reflectometry to directly measure position-resolved linear birefringence of single-mode optical fibers. The technique is suitable for fiber characterization over lengths of tens of kilometers, relying on a fast measurement (

∼

1

s

) with single-ended access to the fiber. The proposed method is experimentally validated with three different commercial single-mode optical fibers.
High acoustic numerical aperture photoacoustic microscopy with improved sensitivity
Authors: Li Mingsheng , Chen Jiangbo , Wang Lidai
Published: December 2019

Limited by the numerical aperture of ultrasonic detection, optical resolution photoacoustic microscopy (OR-PAM) has not achieved optimal sensitivity. To address this problem, we have developed a high acoustic numerical aperture (

∼

0.74

) OR-PAM (HNA-OR-PAM). Via engineering the acoustic lens, we implement the highest acoustic numerical aperture that a spherical concave lens can achieve. The sensitivity of HNA-OR-PAM is improved to around 160%—the state-of-the-art OR-PAM. Without averaging, the new system can image oxygen saturation in vivo with only 10-nJ pulse energy. The improved sensitivity allows us to image weaker absorbers, penetrate deeper, and reduce nonlinear effects induced by high pulse energy. Moreover, the photoacoustic view angle is augmented to 51.8 deg and makes tilted features more visible. We validate the improved view angle in both a phantom study and brain imaging.
Universal self-similar asymptotic behavior of optical bump spreading in random medium atop incoherent background
Authors: Li Xiaofei , Ponomarenko Sergey A. , Xu Zhiheng , Wang Fei , Cai Yangjian , Liang Chunhao
Published: December 2019

We demonstrate theoretically that the average spatial intensity profile of any partially coherent optical beam, composed of a finite-power bright intensity bump atop a fluctuating background, evolves into a universal self-similar Gaussian shape upon long-term propagation in a statistically homogeneous, isotropic linear random medium. The result depends neither on the degree of the background spatial coherence nor on the strength of the medium turbulence. To our knowledge, this is the first demonstration of universal self-similar asymptotics in linear random media.
Orthogonally polarized frequency combs in a mode-locked VECSEL
Authors: Vladimirov Andrei G. , Panajotov Krassimir , Tlidi Mustapha
Published: December 2019

We introduce a spin–flip model for a vertical-external-cavity surface-emitting laser (VECSEL) with a saturable absorber. We demonstrate the possibility, due to the spin–flip dynamics, to generate two orthogonally linearly polarized frequency combs in the mode-locked regime. The two combs are shifted in wavelength due to the birefringence in the VECSEL gain and/or saturable absorption mirror. We show that the polarization degree of freedom may also lead to several pulses being generated per roundtrip in the two orthogonal linear polarizations and to more complicated dynamics with both linear polarizations excited.
Dynamics of optical polarizability of liquid water exposed to intense laser light
Authors: Kononenko Vitali V. , Gololobov Viktor M. , Konov Vitaly I.
Published: December 2019

Variations in the optical properties of pure water induced by a femtosecond laser (wavelength 800 nm, intensity

∼

10

12

W

/

c
m

2

) were studied by a pump–probe interferometric technique. Laser photoionization was shown to increase both the refractive index and absorbance of the water. While the absorption dynamics were found to be in a good agreement with previous studies, the temporal behavior of the refractive index exhibited novel features. It was found that the always-positive refractive index contains distinct peaks at the beginning and end of the laser pulses. This behavior was attributed to the Kerr effect in water molecules and in wet/hydrated electrons produced by photoionization, respectively.
Spatially controlled fabrication of single NV centers in IIa HPHT diamond
Authors: Trofimov Sergei D. , Tarelkin Sergey A. , Bolshedvorskii Stepan V. , Bormashov Vitaly S. , Troshchiev Sergey Yu. , Golovanov Anton V. , Luparev Nikolai V. , Prikhodko Dmitrii D. , Boldyrev Kirill N. , Terentiev Sergey A. , Akimov Alexey V. , Kargin Nikolay I. , Kukin Nikolay S. , Gusev Alexander S. , Shemukhin Andrey A. , Balakshin Yuri V. , Buga Sergei G. , Blank Vladimir D.
Published: December 2019

Single NV centers in HPHT IIa diamond are fabricated by helium implantation through lithographic masks. The concentrations of created NV centers in different growth sectors of HPHT are compared quantitatively. It is shown that the purest {001} growth sector (GS) of HPHT diamond allows to create groups of single NV centers in predetermined locations. The {001} GS HPHT diamond is thus considered a good material for applications that involve single NV centers.
Treatment of experimentally induced diabetic wound infected with methicillin-resistant Staphylococcus aureus using Aloe vera, Apium graveolens, and Sauropus androgynus extracts in rats
Authors: Prakoso Yos Adi , Kurniasih Kurniasih , Wijayanti Agustina Dwi , Kristianingrum Yuli Purwandari
Published: December 2019

Background and Aim: One of the complications of diabetes mellitus is diabetic ulcer. Diabetic ulcer is commonly infected by infectious agents, especially methicillin-resistant Staphylococcus aureus (MRSA). This study aimed to evaluate the potential effects of alcoholic extracts of Aloe vera, Apium graveolens, and Sauropus androgynus on promoting wound healing in a diabetic wound infected with MRSA.

Materials and Methods: A total of 60 male Sprague-Dawley rats (6 months old, weighing 250-300 g) were injected with 65 mg/kg body weight of streptozotocin to induce diabetes. On day 7, the backs of the rats were shaved, and two circular wounds (4 mm in diameter) were created on their back, which were infected with MRSA. The rats were divided into six groups: Group I = control, Group II = treated with cream base without extract, Group III = treated with 2% A. vera cream, Group IV = treated with 2% A. graveolens cream, Group V = treated with 2% S. androgynus cream, and Group VI = treated with 2% A. vera + 2% A. graveolens + 2% S. androgynus cream. The wounds were treated twice a day for 14 days. The data were collected on days 7 and 14.

Results: The results showed that all three herbal extracts and their combination decreased wound area and percentage of the wound, increased tensile strength of skin, collagen deposition, vascular endothelial growth factor expression, and skin thickness, and depressed the C-reactive protein profile and cyclooxygenase-2 expression.

Conclusion: A. vera, A. graveolens, and S. androgynus creams can be used as herbal therapies against diabetic wounds infected with MRSA, both as a single and combination treatment.
Comparative modeling and mutual docking of structurally uncharacterized heat shock protein 70 and heat shock factor-1 proteins in water buffalo
Authors: Singh Ravinder , Gurao Ankita , Rajesh C. , Mishra S. K. , Rani Saroj , Behl Ankita , Kumar Vikash , Kataria R. S.
Published: December 2019

Aim: In this study, a wide range of in silico investigation of Bubalus bubalis (BB) heat shock protein 70 (HSP70) and heat shock factor-1 (HSF1) has been performed, ranging from sequence evaluation among species to homology modeling along with their docking studies to decipher the interacting residues of both molecules. Materials and Methods: Protein sequences of BB HSP70 and HSF1 were retrieved from NCBI database in FASTA format. Primary and secondary structure prediction were computed using Expasy ProtParam server and Phyre2 server, respectively. TMHMM server was used to identify the transmembrane regions in HSP70. Multiple sequence alignment and comparative analysis of the protein was carried out using MAFFT and visualization was created using ESPript 3.0. Phylogenetic analysis was accomplished by COBALT. Interactions of HSP70 with other proteins were studied using STRING database. Modeller 9.18, RaptorX, Swiss-Modeller, Phyre2, and I-TASSER were utilized to design the three-dimensional structure of these proteins followed by refinement; energy minimization was accomplished using ModRefiner and SPDBV program. Stereochemical quality along with the accuracy of the predicted models and their visualization was observed by PROCHECK program of PDBsum and UCSF Chimera, respectively. ClusPro 2.0 server was accessed for the docking of the receptor protein with the ligand. Results: The lower value of Grand Average of Hydropathy indicates the more hydrophilic nature of HSP70 protein. Value of the instability index (II) classified the protein as stable. No transmembrane region was reported for HSP70 by TMHMM server. Phylogenetic analysis based on multiple sequence alignments (MSAs) by COBALT indicated more evolutionarily closeness of Bos indicus (BI) with Bos taurus as compared to BI and BB. STRING database clearly indicates the HSF1 as one of the interacting molecules among 10 interacting partners with HSP 70. The best hit of 3D model of HSP70 protein and HSF1 was retrieved from I-TASSER and Phyre2, respectively. Interacting residues and type of bonding between both the molecules which were docked by ClusPro 2.0 were decoded by PIC server. Hydrophobic interactions, protein-protein main-chain-side-chain hydrogen bonds, and protein-protein side-chain-side-chain hydrogen bonds were delineated in this study. Conclusion: This is the first-ever study on in silico interaction of HSP70 and HSF1 proteins in BB. Several bioinformatics web tools were utilized to study secondary structure along with comparative modeling, physicochemical properties, and protein-protein interaction. The various interacting amino acid residues of both proteins have been indicated in this study.
Escenas de lectura y escritura en las clases de Historia. Una mirada sobre las aulas del nivel secundario en la ciudad de Tandil
Authors: Gregorini Vanesa Mariángeles , Cuesta Virginia
Published: December 2019

Desde el campo de la Didáctica de la Historia, este artículo busca explorar las variables que se entretejen en las prácticas de lectura y escritura en el cotidiano de las aulas de Historia en el nivel medio. Algunos de los interrogantes que guían el trabajo son los siguientes: ¿Cuáles son las prácticas de lectura y escritura que los docentes de Historia propician con la intención de que los alumnos aprendan? ¿Qué sentidos, criterios y percepciones anidan detrás de tales prácticas? Esta investigación articula los aportes de la historia de la lectura y de los estudios socioculturales, que han colocado al accionar de los sujetos como motor de cambio de las culturas escolares, y de la etnografía como enfoque privilegiado que permite acceder a las prácticas cotidianas. Constatamos, de este modo, la existencia de prácticas frecuentes que los docentes de Historia despliegan cotidianamente y cuya esencia es el desarrollo de explicaciones dialogadas. En general, son motorizadas por la realización de interrogantes que buscan estimular la lectura y escritura por parte de los alumnos. Proponer líneas de análisis sobre los sentidos y significaciones que sustentan tales prácticas es uno de los propósitos de esta presentación.
Perceived Freedom in Leisure Scale-25: Testing the construct validity for university students
Authors: Yerlisu Lapa Tennur , Tercan Kaas Evren
Published: December 2019

Leisure behaviour is an important study area of the literature recently. In apprehending leisure behaviour, perceived freedom in leisure is a significant dimension. The aim of the study is to test validity of “Perceived Freedom in Leisure Scale (PFLS)” by confirmatory factor analysis (CFA). Study group of this descriptive research consists of 228 university students. Reliability was calculated by internal consistency coefficient Cronbach’s Alpha. As a result of the CFA, modification indexes were examined and items with high error covariance’s were matched (e9-e10, e13-e14, e16-e20). After the modification the results were as follows: χ2/df(χ2/df=1.56) and other fit indexes: AGFI=0.85, GFI=0.87, NFI=0.95, TLI=0.98, CFI=0.98 and RMSEA=0.050. Cronbach’s alpha reliability coefficient was found as 0.93. Consequently after the findings, PFLS could be declared to be used in leisure research as a valid and reliable measurement tool with its 25 items and one factor structure. ​Extended English summary is in the end of Full Text PDF (TURKISH) file.   Özet Serbest zaman davranışının anlaşılmasında serbest zamanda algılanan özgürlük konusu önemli bir boyut olarak görülmektedir. Bu çalışmanın amacı, “Serbest Zamanda Algılanan Özgürlük Ölçeği (SZAÖÖ)”nin geçerliğinin doğrulayıcı faktör analizi (DFA) ile sınanmasıdır. Araştırmanın çalışma grubu 228 üniversite öğrencisinden oluşturmaktadır. Ölçeğin güvenirliğini belirlemek için ise Cronbach alfa iç tutarlık katsayısı hesaplanmıştır. DFA sonucu, modifikasyon endekslerine bakılarak yüksek hata kovaryanslarına sahip maddeler birbirleri ile eşleştirilmiştir (e9-e10, e13-e14, e16-e20). Yapılan modifikasyon endekslerine göre χ2/df (χ2/df=1.56) ve diğer uyum indeks değerleri: AGFI=0.85, GFI=0.87, NFI=0.95, TLI=0.98, CFI=0.98 ve RMSEA=0.050 olarak tespit edilmiştir. Ölçeğin güvenirlik kat sayısı 0.93 olarak saptanmıştır. Araştırma sonucu, 25 madde ve tek faktörden oluşan SZAÖÖ’nin geçerli ve güvenilir bir ölçüm aracı olduğu söylenebilir.
Effects of Mindfulness with Gayatri Mantra on Decreasing Anxiety in the Elderly
Authors: Ketut Candrawati Sang Ayu , Dwidiyanti Meidiana , Widyastuti Rita Hadi
Published: December 2019

Background: Anxiety is one of the psychological problems which can develop in the elderly. If left untreated, it can decrease the productivity and quality of life. Mindfulness with Gayatri mantra is such a complementary therapy which is effective to reduce anxiety in the elderly.  Objective: The purpose of this study was to determine the effects of mindfulness with Gayatri mantra on decreasing anxiety in the elderly Hindus in Bali, Indonesia. Methods: This study employed a one group pre and posttest quasi-experimental design and involved 34 elderly people recruited using a purposive sampling technique. Anxiety was measured using the Geriatric Anxiety Scale (GAS). A t-test statistical analysis was used to analyze the data.   Results: Results showed that there were significant effects of mindfulness with Gayatri mantra on decreasing the anxiety in the elderly Hindus in Bali with a p-value of 0.000 (α-value = 0.05). Conclusion: Mindfulness with Gayatri mantra could decrease anxiety in the elderly Hindus. This therapy can be used as an alternative to prevent the recurrence of anxiety in the elderly.
Determination of relative dissociation energy from electro-optics as a new single-proposed parameter of vegetable oil quality
Authors: Firdausi Ketut Sofjan , Afiefah Izzah , Sugito Heri , Septianti Ririn Widya , Richardina Very , Soesanto Qidir Maulana Binu , Azam Much
Published: December 2019

In this report, we study the electro-optics effect on cooking oil to obtain the relative dissociation energy as a new single proposed parameter of oil quality. The sample was canola oil which had been heated in 0.5 hours, 2 hours and 4 hours. The light source used in the experiment was a green pointer laser with a wave length of 532 nm. The sample was applied to a potential difference from 0 to 9 kV to obtain the electro-optics effect in form of the change of the polarization angle Dq as function of potential difference DV. The relative dissociation energy was obtained from the fitting data of the relative Lenard-Jones potential energy curves represented by change of polarization per unit change of potential difference, Dq/DV. The result shows that the relative dissociation energy is reduced as the oil quality decreased after heated. The relative dissociation energy provides simple physical understanding about electro-optics effect on cooking oils. The study of electro-optics polarization that represents relative Lenard-Jones potential energy is a new but somewhat intuitive, which can be further improved and emphasized for grouping, mapping, and determining various cooking oil quality and halal food due to the lard contamination.
HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53‐dependent mitochondrial apoptosis
Authors: Castelli Marilena , Piobbico Danilo , Chiacchiaretta Martina , Brunacci Cinzia , Pieroni Stefania , Bartoli Daniela , Gargaro Marco , Fallarino Francesca , Puccetti Paolo , Soddu Silvia , Della‐Fazia Maria Agnese , Servillo Giuseppe
Published: December 2019

Apoptotic signalling by p53 occurs at both transcriptional and non‐transcriptional levels, as p53 may act as a direct apoptogenic stimulus via activation of the intrinsic mitochondrial pathway. HOPS is a highly conserved, ubiquitously expressed shuttling protein with an ubiquitin‐like domain. We generated Hops−/− mice and observed that they are viable with no apparent phenotypic defects. However, when treated with chemotherapeutic agents, Hops−/− mice display a significant reduction in apoptosis, suggesting an impaired ability to respond to genotoxic stressors. We show that HOPS acts as a regulator of cytoplasmic p53 levels and function. By binding p53, HOPS inhibits p53 proteasomal degradation and favours p53 recruitment to mitochondria and apoptosis induction. By interfering with importin α, HOPS further increases p53 cytoplasmic levels. Thus, HOPS promotes the p53‐dependent mitochondrial apoptosis pathway by preserving cytoplasmic p53 from both degradation and nuclear uptake.
SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability
Authors: Rossi Francesco , Helbling‐Leclerc Anne , Kawasumi Ryotaro , Jegadesan Nanda Kumar , Xu Xinlin , Devulder Pierre , Abe Takuya , Takata Minoru , Xu Dongyi , Rosselli Filippo , Branzei Dana
Published: December 2019

SMC5/6 function in genome integrity remains elusive. Here, we show that SMC5 dysfunction in avian DT40 B cells causes mitotic delay and hypersensitivity toward DNA intra‐ and inter‐strand crosslinkers (ICLs), with smc5 mutants being epistatic to FANCC and FANCM mutations affecting the Fanconi anemia (FA) pathway. Mutations in the checkpoint clamp loader RAD17 and the DNA helicase DDX11, acting in an FA‐like pathway, do not aggravate the damage sensitivity caused by SMC5 dysfunction in DT40 cells. SMC5/6 knockdown in HeLa cells causes MMC sensitivity, increases nuclear bridges, micronuclei, and mitotic catastrophes in a manner similar and non‐additive to FANCD2 knockdown. In both DT40 and HeLa systems, SMC5/6 deficiency does not affect FANCD2 ubiquitylation and, unlike FANCD2 depletion, RAD51 focus formation. SMC5/6 components further physically interact with FANCD2‐I in human cells. Altogether, our data suggest that SMC5/6 functions jointly with the FA pathway to support genome integrity and DNA repair and may be implicated in FA or FA‐related human disorders.
CrRLK1L receptor‐like kinases HERK1 and ANJEA are female determinants of pollen tube reception
Authors: Galindo‐Trigo Sergio , Blanco‐Touriñán Noel , DeFalco Thomas A , Wells Eloise S , Gray Julie E , Zipfel Cyril , Smith Lisa M
Published: December 2019

Communication between the gametophytes is vital for angiosperm fertilisation. Multiple CrRLK1L‐type receptor kinases prevent premature pollen tube burst, while another CrRLK1L protein, FERONIA (FER), is required for pollen tube reception in the female gametophyte. We report here the identification of two additional CrRLK1L homologues, HERCULES RECEPTOR KINASE 1 (HERK1) and ANJEA (ANJ), which act redundantly to promote pollen tube growth arrest at the synergid cells. HERK1 and ANJ localise to the filiform apparatus of the synergid cells in unfertilised ovules, and in herk1 anj mutants, a majority of ovules remain unfertilised due to pollen tube overgrowth, together indicating that HERK1 and ANJ act as female determinants for fertilisation. As in fer mutants, the synergid cell‐specific, endomembrane protein NORTIA (NTA) is not relocalised after pollen tube reception; however, unlike fer mutants, reactive oxygen species levels are unaffected in herk1 anj double mutants. Both ANJ and HERK1 associate with FER and its proposed co‐receptor LORELEI (LRE) in planta. Together, our data indicate that HERK1 and ANJ act with FER to mediate female–male gametophyte interactions during plant fertilisation.
Розробка типової стратегії розвитку сільськогосподарського підприємства (за методом Хосин Канрі).
Authors: BORYSHKEVYCH IRYNA
Published: December 2019

Сучасні умови глобалізації бізнесу, значна обмеженість ресурсів, посилення конкуренції та прискорення технологічних нововведень вимагають від сільськогосподарських підприємств здатності швидко пристосуватися до мінливих умов зовнішнього середовища. Запорукою їх успішного продуктивного розвитку є забезпечення максимально ефективного використання наявного ресурсного потенціалу. У науці та практиці існує велика кількість різноманітних методичних інструментів, які сприяють покращенню функціонування суб’єктів господарської діяльності. Одним із таких інструментів, що забезпечує досягнення результативного розвитку, формуючи стійкі конкурентні переваги, є стратегія. Йдеться про складну модель, яка охоплює усі процеси на підприємстві. Використання керівниками сільськогосподарських підприємств прогресивних методів розробки стратегії є запорукою успіху її ефективної реалізації та нарощення підприємством конкурентних переваг в ринковому середовищі. У статті проаналізовано існуючі методи стратегічного планування, в основі яких лежить різна методика побудови стратегій. Проведено характеристику наступних методів: ресурсний метод, цільовий метод, метод екстраполяції, інтерполятивний метод, пробно-статистичний метод, критеріальний метод, нормативний метод, балансовий метод, матричний метод і побудова стратегічного плану. На основі опрацьованих джерел досліджено метод Хосин Канрі, що базується на застосуванні циклу Демінга та являє собою концепцію циклічного управління. Розроблено типову стратегію розвитку сільськогосподарського підприємства у вигляді Х-матриці. Дана стратегія розрахована на 3 роки і включає стратегічні і тактичні цілі, процеси і результати, між якими встановлені відповідні кореляційні зв’язки. Серед стратегічних цілей, що є типовими для сільськогосподарських підприємств виокремлено наступні: підвищення ефективності бізнесу, підвищення ефективності збутової діяльності, впровадження інноваційних технологій у виробництво та оптимізація бізнес-процесів. Відповідно керівництво сільськогосподарських підприємств можуть формувати більшу кількість перспективних цілей, виходячи із потреб суб’єктів господарювання. Отримані результати формують підґрунтя для подальших досліджень механізму формування та впровадження стратегії розвитку сільськогосподарських підприємств.
ORGANIZATIONAL AND ECONOMIC MECHANISMS OF TRANSPORT SYSTEM DEVELOPMENT BASED ON LOGISTICS
Authors: IRTYSHCHEVA INNA , ISHCHENKO OLENA , BARABANOVA JULIA
Published: December 2019

It is determined that the existence of a developed transport and logistics infrastructure is one of the defining dominants of the effective functioning of the transport and logistics system at the regional, national and international level, provides effective supply, marketing, production and social communications between the subjects of economic activity.

It is proved that the main directions of state policy implementation in the field of transport and logistics are: directions of innovative development of transport and logistics technologies on energy-saving and environmentally safe principles; construction of efficient economic systems in accordance with the principles of logistics and marketing; development of strategic planning; improvement of regulatory policy.

Institutional, organizational and economic mechanisms for ensuring the effective development of national transport and logistics systems have been researched and systematized, among which the following have been identified as priorities: the development of public-private partnerships and decentralization reform, which will solve the problems of financing infrastructure development, the formation of multi-branch integration structures (transport-logistics clusters, transport hubs and logistics-outsourcing platforms), which will improve the quality of transport and logistics services, intensification of the integration processes of the transport and logistics system in the international transport of the network, which will increase the competitiveness of the national economy, increase in productivity of transit potential and attraction of foreign investments in the development of the industry.
INFORMATION-ANALYTICAL PROVISION OF FINANCIAL SECURITY OF INDUSTRIAL ENTERPRISES: DETERMINANTS, EVALUATION OF INDICATORS AND MECHANISMS OF STRENGTH
Authors: VIVCHAR OKSANA , KRZYWKOWSKA JUSTYNA , MYKHAILYSHYN LILIIA , KOHUT-FERENS OKSANA
Published: December 2019

Conceptual aspects of industrial enterprises financial security are considered, features of industrial enterprises financial security information and analytical support functioning are determined. On the basis of which a structural and logical scheme of information and analytical support of an industrial enterprise financial security in modern transformational conditions is proposed.

The analysis of the current state of major external and internal threats identification is carried out. Based on the results of the analysis, it was found that the most risky components of an industrial enterprise financial security are investment and credit, since these components carry the greatest number of risks.

Also, a comprehensive analytical assessment of the information and analytical support formation of the country’s Western region business structures financial security was made. The calculations make it possible to identify the main problematic aspects of the functioning of enterprises and threats to their financial security and to develop measures to strengthen it. The economic efficiency of the information and analytical support system introduction of industrial enterprises financial security with consideration of strategic and tactical vectors of development, and also depends on completeness, reliability, timeliness of the information component. The algorithm of forming information and analytical support of industrial enterprises financial security assessment with consideration of software is investigated. On the basis of which a multi-vector mechanism of information and analytical support of industrial enterprises financial security in modern conditions of turbulence of economic processes is proposed. This will make the decision-makers informed, both strategic and tactical, operational.