bluuebunny/crossref_metadata_2025 huggingface dataset:
Extending RiC-O to Model Historical Architectural Archives: The ITDT Ontology
Authors: Mikhaylova Daria , Metilli Daniele
Published: July 2023

Historical architectural archives enjoy attention from diverse audiences, acting as a primary source of information for architects, historians, public authorities, and common citizens alike. In Italy, the interest in architectural archives has grown slowly but steadily for the last 20 years. However, architectural archives do not generally follow the trend common for museums and galleries in publishing digitized materials and providing standard metadata for individual records. The information that is available online usually includes only an archival finding aid, instead of metadata about the individual records, or fully digital versions of the records. While cataloguing standards for archival descriptions of architectural records have existed at least since the 1980s, the rise of Linked Open Data as a framework for publishing cultural heritage data has allowed archivists to enhance these archival descriptions with richer contextual information and links to external knowledge bases. In this paper we present the ITDT ontology, an extension of the Records in Contexts Ontology that facilitates the representation of architectural records and of the context related to architectural projects, its process, and participating entities. We discuss the application of the ontology to the project files of Italian architect and engineer Dino Tamburini (1924–2011), and the creation of a digital archive offering multiple perspectives over the records.
Improving the Efficiency of Quantum Circuits for Information Set Decoding
Authors: Perriello Simone , Barenghi Alessandro , Pelosi Gerardo
Published: July 2023

Code-based cryptosystems are a promising option for Post-Quantum Cryptography, as neither classical nor quantum algorithms provide polynomial time solvers for their underlying hard problem. Indeed, to provide sound alternatives to lattice-based cryptosystems, U.S. National Institute of Standards and Technology (NIST) advanced all round 3 code-based cryptosystems to round 4 of its Post-Quantum standardization initiative. We present a complete implementation of a quantum circuit based on the Information Set Decoding (ISD) strategy, the best known one against code-based cryptosystems, providing quantitative measures for the security margin achieved with respect to the quantum-accelerated key recovery on AES, targeting both the current state-of-the-art approach and the NIST estimates. Our work improves the state-of-the-art, reducing the circuit depth by 2
19
to 2
30
for all the parameters of the NIST selected cryptosystems, mainly due to an improved quantum Gauss–Jordan elimination circuit with respect to previous proposals. We show how our Prange’s-based quantum ISD circuit reduces the security margin with respect to its classical counterpart. Finally, we address the concern brought forward in the latest NIST report on the parameters choice for the McEliece cryptosystem, showing that its parameter choice yields a computational effort slightly below the required target level.
Quality and Efficiency Control of Electrodeposition and Electrodissolution of Ni on a Ternary Composite Electrode Followed by Digital Video Electrochemistry
Authors: Agrisuelas Jerónimo , García-Jareño José J. , Piedras Manuel , Vicente Francisco
Published: July 2023

The quality of metal electrodeposits on different surfaces depends on the configuration and composition of the electrochemical bath, but also on the control of experimental variables that can affect the electrode processes taking place. In this work, we have studied the electrodeposit of nickel on a polypropylene|graphite|copper (PP|G|Cu) ternary composite electrode. Together with the resistive behavior of the electrode, the nickel electrodeposition presents extra difficulties as a low reduction potential and numerous and possible chemical reactions with the medium to form passive layers or aqueous complexes. The use of digital video electrochemistry (DVEC) has allowed detecting some issues during the electrodeposition and electrodissolution processes such as the non-uniform growth of Ni due to the electrode configuration, secondary and oscillatory electrochemical reactions caused by the subproducts in the auxiliary electrode or the effect of the formation of hydrogen bubbles. The estimation of electrodeposition efficiency from DVEC and a possible electrodissolution mechanism are discussed.
Mucus Hypersecretion in Chronic Obstructive Pulmonary Disease and Its Treatment
Authors: Shah Binay Kumar , Singh Bivek , Wang Yukun , Xie Shuanshuan , Wang Changhui
Published: July 2023

Most patients diagnosed with chronic obstructive pulmonary disease (COPD) present with hallmark features of airway mucus hypersecretion, including cough and expectoration. Airway mucus function as a native immune system of the lung that severs to trap particulate matter and pathogens and allows them to clear from the lung via cough and ciliary transport. Chronic mucus hypersecretion (CMH) is the main factor contributing to the increased risk of morbidity and mortality in specific subsets of COPD patients. It is, therefore, primarily important to develop medications that suppress mucus hypersecretions in these patients. Although there have been some advances in COPD treatment, more work remains to be done to better understand the mechanism underlying airway mucus hypersecretion and seek more effective treatments. This review article discusses the structure and significance of mucus in the lungs focusing on gel-forming mucins and the impacts of CMH in the lungs. Furthermore, we summarize the article with pharmacological and nonpharmacological treatments as well as novel and interventional procedures to control CMH in COPD patients.
Physiochemical Characterization of Ethiopian Mined Kaolin Clay through Beneficiation Process
Authors: Ayalew Adane Adugna
Published: July 2023

Kaolin mineral is a commercially solid powder with a comparatively low level of purity and is regularly used for a variety of applications, including filler, paints, ceramics, adsorbents, and paper. In Ethiopia, the kaolin clay mineral is significant for financial growth as the raw material used in the industry sector. However, slight consideration was given to the chemical, physical, mineralogical, and morphological properties of kaolin. In this study, the property of kaolin is investigated by using advanced instruments such as X-ray diffraction (XRD), X-ray fluorescence analysis (XRF), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and differential thermogravimetric analysis (DTA). Based on the XRF test, the main component of kaolin clay contains SiO2 (58.73%), Al2O3 (24.35%), K2O (5.36%), and other impurities, including Fe2O3 (2.06%) and TiO2 (0.13%). The FTIR spectra displayed the functional groups Si-O, Al-OH, Al-O, and Si-O-Al. The XRD diffractogram identified kaolin clay as the main mineral phase in the existence of quartz, halloysite, and chlorite.
Integrated Multi-omics Analysis of Early Lung Adenocarcinoma Links Tumor Biological Features with Predicted Indolence or Aggressiveness
Authors: Senosain Maria-Fernanda , Zou Yong , Patel Khushbu , Zhao Shilin , Coullomb Alexis , Rowe Dianna J. , Lehman Jonathan M. , Irish Jonathan M. , Maldonado Fabien , Kammer Michael N. , Pancaldi Vera , Lopez Carlos F.
Published: July 2023

Lung adenocarcinoma (LUAD) is a heterogeneous group of tumors associated with different survival rates, even when detected at an early stage. Here, we aim to investigate the biological determinants of early LUAD indolence or aggressiveness using radiomics as a surrogate of behavior. We present a set of 92 patients with LUAD with data collected across different methodologies. Patients were risk-stratified using the CT-based Score Indicative of Lung cancer Aggression (SILA) tool (0 = least aggressive, 1 = most aggressive). We grouped the patients as indolent (x ≤ 0.4, n = 14), intermediate (0.4 > x ≤ 0.6, n = 27), and aggressive (0.6 > x ≤ 1, n = 52). Using Cytometry by time of flight (CyTOF), we identified subpopulations with high HLA-DR expression that were associated with indolent behavior. In the RNA sequencing (RNA-seq) dataset, pathways related to immune response were associated with indolent behavior, while pathways associated with cell cycle and proliferation were associated with aggressive behavior. We extracted quantitative radiomics features from the CT scans of the patients. Integrating these datasets, we identified four feature signatures and four patient clusters that were associated with survival. Using single-cell RNA-seq, we found that indolent tumors had significantly more T cells and less B cells than aggressive tumors, and that the latter had a higher abundance of regulatory T cells and Th cells. In conclusion, we were able to uncover a correspondence between radiomics and tumor biology, which could improve the discrimination between indolent and aggressive LUAD tumors, enhance our knowledge in the biology of these tumors, and offer novel and personalized avenues for intervention.

Significance:

This study provides a comprehensive profiling of LUAD indolence and aggressiveness at the biological bulk and single-cell levels, as well as at the clinical and radiomics levels. This hypothesis generating study uncovers several potential future research avenues. It also highlights the importance and power of data integration to improve our systemic understanding of LUAD and to help reduce the gap between basic science research and clinical practice.
Proteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor–positive Breast Cancers for Targeted Treatment
Authors: Kim Beom-Jun , Zheng Ze-Yi , Lei Jonathan T. , Holt Matthew V. , Chen Anran , Peng Jianheng , Fandino Diana , Singh Purba , Kennedy Hilda , Dou Yongchao , Chica-Parrado María del Rosario , Bikorimana Emmanuel , Ye Dan , Wang Yunguan , Hanker Ariella B. , Mohamed Nada , Hilsenbeck Susan G. , Lim Bora , Asirvatham Jaya Ruth , Sreekumar Arun , Zhang Bing , Miles George , Anurag Meenakshi , Ellis Matthew J. , Chang Eric C.
Published: July 2023

NF1 is a key tumor suppressor that represses both RAS and estrogen receptor-α (ER) signaling in breast cancer. Blocking both pathways by fulvestrant (F), a selective ER degrader, together with binimetinib (B), a MEK inhibitor, promotes tumor regression in NF1-depleted ER+ models. We aimed to establish approaches to determine how NF1 protein levels impact B+F treatment response to improve our ability to identify B+F sensitive tumors. We examined a panel of ER+ patient-derived xenograft (PDX) models by DNA and mRNA sequencing and found that more than half of these models carried an NF1 shallow deletion and generally have low mRNA levels. Consistent with RAS and ER activation, RET and MEK levels in NF1-depleted tumors were elevated when profiled by mass spectrometry (MS) after kinase inhibitor bead pulldown. MS showed that NF1 can also directly and selectively bind to palbociclib-conjugated beads, aiding quantification. An IHC assay was also established to measure NF1, but the MS-based approach was more quantitative. Combined IHC and MS analysis defined a threshold of NF1 protein loss in ER+ breast PDX, below which tumors regressed upon treatment with B+F. These results suggest that we now have a MS-verified NF1 IHC assay that can be used for patient selection as a complement to somatic genomic analysis.

Significance:

A major challenge for targeting the consequence of tumor suppressor disruption is the accurate assessment of protein functional inactivation. NF1 can repress both RAS and ER signaling, and a ComboMATCH trial is underway to treat the patients with binimetinib and fulvestrant. Herein we report a MS-verified NF1 IHC assay that can determine a threshold for NF1 loss to predict treatment response. These approaches may be used to identify and expand the eligible patient population.
Análise comportamental de atiradores em escola e bullying
Authors: Khozam Karina Timóteo , Miziara Carmen Silvia Molleis Galego , Miziara Ivan Dieb
Published: July 2023

Atiradores em massa nas escolas, ou school shooters, são autores de um fenômeno raro, mas com grande impacto midiático. Sem explicações simplistas nem perfil único que possa prever suas ações, a motivação do agressor é incerta e suas vítimas, aleatórias, na maioria. Por meio de revisão narrativa de literatura, foram abordados diferentesaspectos referentes ao comportamento dos atiradores e a relação intrínseca com o bullying. Os resultados mostraram um padrão evolutivo de entendimento. Os primeiros estudos mostraram uma relação entre o comportamento agressivo do atirador em escolas e as vivências sofridas de solidão, desamparo e incompreensão, quase que vitimizando os autores. Estudos mais recentes não excluem o bullying, mas abrem as possibilidades para outros fatores aditivos que merecem ser analisados pelos responsáveis parentais e escolares.
The Design Problem Revisited
Authors: Lutfi Dina
Published: July 2023

The terms “problem and solution” are omnipresent the world over in various design disciplines and designers often position themselves as problem solvers. Through a rigorous exploration of different perspectives on the problem-solution model and its impact, this article revisits how designers define, perceive, and consequently practice design. It closely explores how frequently propagated terminology and perceptions can impact designers and their work—educationally and professionally. The article also presents alternative approaches to thinking about and practicing design.
Mediating Interpersonal Synchronization in Children through a Full-Body Mixed Reality System: Analysis of the Pre-Interactive Mandala Experience
Authors: Gali Olga , Ercan Sena Beste , Atherton Gray , Cross Liam , Sayis Batuhan , Heaton Pamela , Pares Narcis
Published: July 2023

Interpersonal entrainment (IPE), motor synchronization to a common rhythm, can be used to strengthen the ability to communicate and coordinate actions between citizens. Different studies show how children's and adults’ behaviors changed positively by increasing their cooperation, helpfulness, and affiliation levels after performing activities in synchrony. However, those activities are often affected by the mediation of a researcher. This problem can be addressed by using new technologies such as mixed reality (MR) full-body systems. The aim of this study was to develop a playful MR pre-interactive (noninteractive visual/auditory cues) experience, the Mandala, to promote IPE. Sixty-six children were presented, in groups of four, with one of the conditions: async movements and ambient music (control) or sync movements accompanied by rhythmic (experimental 1) or ambient music (experimental 2). We analyzed the children's ability to follow the visual elements well (temporal pattern and precision), the good use of the interactive object, and their level of synchrony. The results show how the children followed the visual pattern well and accurately, used the interactive object as proposed, and achieved high levels of synchrony. We provided initial insights on how full-body MR systems can be used to promote IPE without an external facilitator.
Analyse linguistique d’un corpus épistolaire en moyen arabe
Authors: Guerrero Jairo
Published: July 2023

Dans cet article nous présentons l’analyse linguistique d’un corpus de lettres luso- marocaines partiellement numérisées et conservées aux archives centrales portugaises. Ces documents datent tous de la première moitié du Xe/XVIe siècle et sont écrits en moyen arabe, un registre de langue écrite qui se caractérise par l’utilisation combinée de la langue classique et d’éléments dialectaux. L’objectif final de cette étude est de proposer quelques pistes pour retracer l’histoire des parlers arabes marocains modernes.
Taxonomic review of the Miltochrista hollowai and M. curvifascia species-groups with descriptions of two new species from India (Erebidae: Arctiinae: Lithosiini)
Authors: SINGH SANTOSH , KIRTI JAGBIR SINGH , JOSHI RAHUL , SINGH NAVNEET
Published: July 2023

The Miltochrista hollowai (Kirti & Gill, 2009) and M. curvifascia (Hampson, 1891) species-groups are reviewed, and two new species belonging to the M. hollowai species-group i.e., Miltochrista madathumala sp. nov. and M. kumarkaustubhi sp. nov. are described from South India. The female of M. paraarcuata is illustrated and diagnosed for the first time. Illustrations of adults and genitalia as well as diagnoses are provided for all the species considered.
A new deep-water species of Discias Rathbun, 1902 (Decapoda: Caridea: Disciadidae) from the Gulf of Aqaba, northern Red Sea
Authors: ANKER ARTHUR
Published: July 2023

A new species of the caridean shrimp genus Discias Rathbun, 1902 is described from the Gulf of Aqaba in the northern Red Sea off the coast of Saudi Arabia. Discias forsskali sp. nov. is unique within the genus Discias, combining the following morphological features: (1) rostrum elongate, triangular, pointed distally, non-lanceolate, with serrations on the lateral margins extending onto the orbital margin; (2) posterodorsal margins of all pleonites smooth, unarmed; (3) mandible with well-developed, biarticulated palp; (4) dactylus of third to fifth pereiopods with row of spinules on ventral margin, dactylus of fifth pereiopod smooth dorsally; (5) uropodal exopod with straight, non-serrated lateral margin; and (6) posterior margin of telson with nine (four pairs + one) spiniform setae. The holotype and single known specimen of the new species, an ovigerous female, was collected by ROV at a depth of 387.4 m.
Symbolic Rewards as Migration Diplomacy: Crisis and Containment in EU–Turkey Migration Cooperation
Authors: Fine Shoshana
Published: July 2023

This article aims to understand why the Turkish state actors participated in the 2016 European Union (EU)–Turkey agreement in the name of managing the so-called migration crisis. At first glance, this move may seem contrary to its interests in a context where Turkey’s accession to the EU was no longer a probable political project. In explaining Turkish state actors’ enthusiasm for the 2016 agreement which led to the containment of migrants and refugees in Turkey, the literature often highlights the question of material gains, both economic and strategic. In this article, I argue that the symbolic dimension is critical for understanding why Turkish actors participated in migration containment away from EU borders. I offer the notion of symbolic rewards to make sense of this process. These rewards brought Turkey into a “good” migration governance in-group. This article argues that there was incremental consolidation of Turkey’s active role in European migration governance well before the crisis. My findings are based on ethnographic data comprising interviews as well as participant observation at the head office of an international migration organization.
Red Palms’ Syndrome and Red Fingers’ Syndrome: A Mini Review
Authors: Bilancini Salvino , Lucchi Massimo , Tucci Sandro , Pomella Federica , Vittori Giulia , Mollo Pierluigi Edgard , Trevisan Giusto
Published: July 2023

Red palms syndrome consists of an intense redness on the palms of the hands and, occasionally, the soles of the feet. This infrequent condition may be primary or secondary. The primary forms are either familial or sporadic. They are always benign and do not require treatment. The secondary forms may have a poor prognosis related to the underlying disease, for which early identification and treatment are imperative. Red fingers syndrome is also rare. It manifests as a persistent redness on the fingers or toes pulp. It is typically secondary either to infectious diseases like human immunodeficiency virus, hepatitis C virus and chronic hepatitis B or to Myeloproliferative Disorders, such as Thrombocythemia and Polycythemia vera. Manifestations spontaneously regress over months or years without trophic alterations. Treatment is limited to that of the underlying condition. Aspirin has been shown effective in Myeloproliferative Disorders.
Epic Battles in Two-Sided Markets
Authors: Alderman Brianna L. , Blair Roger D.
Published: July 2023

Epic Games, the developer of the enormously popular Fortnite, sued Apple for allegedly violating §1 and §2 of the Sherman Act. The central issue was Apple’s requirement that iPhone-compatible apps be purchased in its App Store. Because Apple collects a 30 percent ad valorem tax on each transaction, Epic Games offered an alternative payment option to iPhone owners through the Fortnite app so that consumers could avoid Apple’s 30% fee. When Apple expelled Epic Games from its App Store, Epic sued. In this article, we examine the flawed analysis of the District Court, which can be traced to a fundamental misunderstanding of economic principles.
Introduction to a Special Issue on Labor in the Middle East and North Africa: Precarity, Inequality, and Migration
Authors: Bishara Dina
Published: July 2023

Despite its political and strategic importance, the Middle East and North Africa (MENA) region has been largely absent from cross-regional comparative treatments of industrial and labor relations. This special issue builds on a rich, multidisciplinary, and methodologically diverse body of research on labor and employment in the MENA, bringing together a collection of cutting-edge work in this field. The goal is to bring the study of the MENA into conversation with international and comparative scholarship on industrial and labor relations and to encourage more systematic inclusion of the MENA in comparative work. Drawing on research on Egypt, Jordan, Morocco, Tunisia, Israel, and the Gulf states, contributors to this special issue advance comparative scholarship on migration, labor market outcomes, worker agency, and the relationship between unions and precarious workers. This introductory essay situates these contributions in the context of three bodies of research in the study of labor in the MENA: resistance and contentious activism, labor market challenges, and migration.
Fatigue strength of self-piercing riveted joints of carbon fiber reinforced composite and Al5052 alloy plates
Authors: Lee Ju-Ho , Oh Man-Jin , Kim HoKyung
Published: July 2023

Self-piercing riveting (SPR) is an alternative to the conventional spot-welding method when joining sheets of dissimilar materials. In this study, the static and fatigue strengths of the SPR joints of carbon fiber composite laminate and an Al5052 aluminum alloy plate under various loading conditions were evaluated. Fatigue test results show that the load amplitudes, corresponding to the fatigue endurance limit, based on a lifetime of one million cycles, were 680  N, 323  N, and 305  N for loading angles of 0°, 45° and 90°, respectively, with corresponding fatigue ratios of the joints of 33%, 23% and 24%. The fatigue strengths at the loading angles of 45°, and 90° in terms of the equivalent stress intensity factor were found to be much higher than those at a loading angle of 0°. This is partially due to the difference in the fatigue failure modes. Regarding the fatigue strength designs of SPR joints consisting of composite laminate and aluminum alloy plates under various loads, it can be suggested that the tensile-shear strengths dominate the SPR fatigue strengths of the joints because they are highly vulnerable to tensile-shear loading.
End of Life in Boys and Young Men With Duchenne Muscular Dystrophy – The Perspective of Dying Men and Their Families: A Systematic Review and Thematic Synthesis of Qualitative Evidence
Authors: Chrastina Jan , Haroková Martina
Published: July 2023

Understanding the perceptions and experiences related to the end of life (EoL) of boys and men with Duchenne muscular dystrophy from their own and/or family perspective is limited based on the available qualitative empirical studies. This systematic review was done with a thematic synthesis of qualitative evidence according to the PRISMA Statement Guidelines and the SPIDER search tool. The review included empirical, qualitative, and relevant full-text studies published in 2000–2023 in the EBSCO Discovery Service, ISI Web of Science, Scopus, PubMed, and ProQuest databases. From o total of eight included qualitative studies, four main key themes were identified: “Being a parent/caregiver” – psychosocial aspects, needs, and experiences; “Communication about EoL with healthcare and other professionals” – positive experiences and personal shortcomings; “Discussions about…” – the issue of EoL, dying and death; and “End of life” – end-of-life care, planning and the need for palliative care.
Effects of a Mentoring Program for Black, Indigenous, and People of Color and First-Generation Public Health Students
Authors: Grilo Stephanie , Bryant Monét , Garbers Samantha , Wiggin Maggie , Samari Goleen
Published: July 2023

Objectives:

Among graduate public health students, Black, Indigenous, and other people of color (BIPOC; including Latinx, Asian, Middle Eastern and North African, Native Hawaiian and Pacific Islander, and multiracial) experience educational and personal challenges that require institutional support and reform. The objective of this study was to evaluate the effects of an antiracist mentorship program on the sense of belonging and overall experience among BIPOC and first-generation students at Columbia University Mailman School of Public Health in New York City.

Methods:

We used 2 data sources to retrospectively evaluate experiences of BIPOC and first-generation graduate students: the 2021 Mentoring of Students and Igniting Community (MOSAIC) Student Survey (n = 39), which collected data on experiences of students who participated in the MOSAIC program, and the 2016-2020 Graduate Exit Surveys (n = 1222), which collected data on graduating students’ experiences, satisfaction, and perspectives on diversity, equity, and inclusion. A difference-in-difference analysis compared overall experience, public health career preparedness, quality of life, and department satisfaction among all students before (2016-2018) and after (2019-2020) implementation of the MOSAIC program.

Results:

Satisfaction among graduate students attributable to the MOSAIC program introduced in 2019 increased by about 25%. Compared with students who had not been exposed to MOSAIC, students exposed to MOSAIC had a 25% positive difference ( P = .003) in overall graduate school experience, a 28% difference ( P < .001) in quality of life, and a 10% difference ( P = .001) in satisfaction with their departments.

Conclusion:

Mentorship for BIPOC and first-generation public health graduate students offers an effective strategy to improve student experiences and satisfaction with graduate departments and, ultimately, may help students meet educational and professional goals.
Angry Worship and Preaching: Embodying Context and Text in Liturgy – Part 2
Authors: Wepener Cas
Published: July 2023

In the second part of this article exploring angry liturgy and preaching, a preliminary theory of liturgical and homiletical praxis for angry liturgy and preaching is developed. The theoretical exploration of anger from Part 1 is developed by means of explicating the themes of angry listening, angry hermeneutics, practices, and strategies for angry preaching, and angry liturgy as a liturgical and homiletical praxis theory.
Ultrasonographic Findings and Prognosis of Metastases to the Thyroid Gland
Authors: Xie Wenting , Wang Yaoqin , Du Zhongshi , Chen Yijie , Wu Yu , Zhu Dongdong , Tang Lina
Published: July 2023

Metastases to the thyroid gland (MTT) are uncommon in clinical practice. The ultrasound (US) features are easily confused with primary thyroid malignancy, Hashimoto’s thyroiditis, and other thyroid diseases. Therefore, this study aimed to assess the role of US and analysis of prognosis of MTT. A total of 45 patients with MTT in the database between July 2009 and February 2022 at the Fujian Cancer Hospital were reviewed. US examinations were performed only on 20 patients, who were finally included in our study. Among the 20 patients, nine were male, and eleven were female. According to US characteristics, metastases to the thyroid gland were divided into nodular and diffuse types (17 and 3 cases, respectively). Three lesions (17.6%) had circumscribed margins, and 14 (82.4%) were uncircumscribed. Three lesions (17.6%) were regular in shape, and 14 (82.4%) were irregular. Nine metastases (52.9%) were a taller-than-wide shape, and eight (47.1%) were not a taller-than-wide shape. Ten lesions (58.8%) had rich vascularity, and seven (41.2%) had absence/not rich vascularity. The mean overall survival (OS) from the time of MTT diagnosis was 22 months (95% confidence interval: 5.95–38.05). The 1-, 3-, and 5-year OS after metastasis was 68.1%, 25.5%, and 17%, respectively. The prognosis of MTT was poor, which is closely related to the characteristics of the primary tumor and metastatic disease. The US findings and US-guided core needle biopsy may be useful in diagnosing MTT in patients with a history of the malignant tumors.
Biological properties of extracts from the mixture of honey and berries of Pistacia lentiscus
Authors: Ayad Rabha , Amessis-Ouchemoukh Nadia , Otmani Amar , Guenaoui Nawel , Sadou Dyhia , Madani Khodir , Ouchemoukh Salim
Published: July 2023

Background: Honey is a product of the hive elaborated by the bees of the species Apis mellifera. As well as Pistacia lentiscus, is a species widely used in traditional medicine that is part of a large family of Anacardiaceae. Aims: To determine the biological properties including the antioxidant activity of the mixture of the extract of P. lentiscus berries associated with honey at different concentrations (0.5%, 2%, 4%, 8% and 12%). Methods: Physicochemical parameters and phenolic compound amounts. The antioxidant activities (reducing power, FRAP, CUPRAC, TAC, DPPH, ABTS, and ferrozine) were also tested. Results: According to the physico-chemical parameters, the honey and the mixture analyzed are in conformity with the international standards. The results of the antioxidant assay gave a significant content of total phenolic compounds for the H/DP mixtures, the sample of honey alone analyzed exerts a weak antioxidant activity compared to the two mixtures made. Conclusion: The honey and Pistacia compound constitute an important source of antioxidants which intensifies very significantly the antioxidant activity of the blend.
High-risk human papillomavirus infection among Nigerian women: A systematic review and meta-analysis
Authors: Ezechi Oliver , Akinsolu Folahanmi , Salako Abideen , Abodunrin Olunike , Adewole Ifeoluwa , Olagunju Mobolaji , Okunbor Hilary , Sanni-Adeniyi Rukayat , Zamba Emmanuella , Njuguna Diana Wangeshi , Eleje George
Published: July 2023

Objective

We conducted a systematic review and meta-analysis to determine the prevalence of high-risk human papillomavirus (hrHPV) infection and its associated risk factors among Nigerian women.

Methods

Databases including PubMed, Web of Science, Scopus, and CINAHL were searched for studies published between 01 January 2001 and 31 December 2022, that had reported hrHPV infection and associated risk factors among women in Nigeria from ages of 25 to 65 years.

Results

Of the 136 records initially retrieved, 18 were eligible for analysis. The prevalence of hrHPV genotypes was 25%, and for hrHPV 16 and 18, were 9% and 10%, respectively. The prevalence of hrHPV among HIV+ve women was 71%. The most common risk factors for hrHPV were age at coitarche and multiple sex partners.

Conclusion

hrHPV prevalence is high in women in Nigeria and common among those HIV+ve. Rapid screening for hrHPV genotypes is recommended, and multivalent HPV vaccines should be considered for women.
Follicular dysplasia and hair loss in white-tailed deer (Odocoileus virginianus)
Authors: Deering Kathleen M. , Clarke Lorelei L. , Lennix Shawn V. , Layne Elizabeth , Long Lindsey , Businga Nancy
Published: July 2023

There have been unpublished reports of a follicular dysplastic syndrome in adult white-tailed deer ( Odocoileus virginianus; WTD), known colloquially as “toothpaste hair disease.” The current report aims to describe the gross and histologic lesions in skin samples from 2 adult WTDs that presented to the Wisconsin Department of Natural Resources and the Wisconsin Veterinary Diagnostic Laboratory with reports of hair loss in 2018. Both cases were grossly alopecic with sparing of the distal extremities and variably the head and neck. Histologic features included hair follicles and adnexa present in relatively normal numbers, dilated and misshapen follicles, and dysplastic hair bulbs. Hair follicles were empty, contained fragmented and irregular hair shafts, or contained concretions of keratin. Hair bulbs were rarely infiltrated by small lymphocytes, suggestive of alopecia areata as a cause of the gross appearance. This condition does not appear to be directly responsible for WTD mortality but presumably would predispose affected animals to greater environmental exposure. Evaluation of additional affected individuals is warranted to further evaluate for features of alopecia areata.
Double fusion, a depth perception mechanism in Panum's limiting case
Authors: Li Huayun , Wang Xin , Li Jing , Lin Wenmin
Published: July 2023

The origin of depth in Panum's limiting case is unclear at present, so we investigated the depth perception mechanism using a triangle type of Panum's stimulus with a slant effect and clear criterion. Experiment 1 explored whether participants can correctly perceive fixation and nonfixation features using the fixation point and quick representation of stimuli, then examined whether participants’ depth judgments supported double fusion or single fusion. The results of Experiment 1 showed that participants could correctly perceive the depth of fixation and nonfixation features. That is, it supported double fusion. In Experiment 2, we examined whether the depth perceived by observers comes from depth contrast. The results of Experiment 2 showed that the depth of the two features perceived after binocular fusion did not originate from the depth contrast. The findings suggest that the depth perception mechanism of Panum's limiting case is more likely to be double fusion.
Platformization as subsumption? A case study of taxi platforms in Oslo, Norway
Authors: Nordli Oppegaard Sigurd M
Published: July 2023

Based on a case study of taxi platforms in Oslo, Norway comprised of interviews with drivers and an ethnographic fieldwork working a driver, this article explores the platformization of the Norwegian taxi industry and the drivers’ working conditions through Marx’s concept of subsumption. In Norway, taxi platforms emerged in an already formally subsumed industry. The platforms have developed a new market segment, and also introduced an additional element in the subsumption of labor, whereby the platforms exert control over the market relations (by determining number of rides, earnings, and potential exclusions) through digital technology. While the platforms’ ‘algorithmic management’ is often described as a technology that might reorganize the world of work, the analysis finds that this form of control does not radically transform the drivers’ labor processes and cannot be seen as an example of what Marx termed real subsumption. However, the platformization of the industry, wherein the platforms appropriate the social and technological conditions of production, might result in a reorganization and transformation corresponding to a real subsumption in the future. The article concludes that exploring platform work through Marx’s notion of subsumption highlights, on one hand, the relation between platforms and workers as characterized by subordination and domination and, on the other, that a detailed and critical assessment of the actual consequences of platform-based control is necessary to capture the contextual dynamics of platformization.
Promoting Cleaner Production in Ports: Analysis of Joint Governance by Central and Local Governments
Authors: Yuan Kebiao , Wang Xuefeng
Published: July 2023

Pollution emissions caused by maritime port activities have attracted increasing attention. To promote cleaner production in port enterprises, based on evolutionary game theory, this paper establishes a tripartite evolutionary game model involving central government, local governments, and port enterprises by analyzing the conflicts of interest among the main stakeholders. Examining the evolutionary game model, we found six combinations of evolutionary stabilization strategies in the system that promote cleaner production in port enterprises. Moreover, we conducted a sensitivity analysis on the relevant parameters of the system and identified the key parameters affecting the stability and equilibrium of the system. The results, from the perspective of interests, show that the cost of cleaner production, fines imposed and subsidies provided by local governments, and incremental benefits are the most significant parameters. In addition, simulation results support the idea that strengthening the risk appetite of port enterprises and local governments and the environmental preferences of local governments is conducive to prompting port enterprises to choose cleaner production more quickly. Finally, we also provide some management insights for policy makers based on the results of sensitivity analysis of relevant parameters affecting the evolution path of the tripartite game. This paper presents an analysis of practices and policies that may be applied to reduce pollution emissions and promote cleaner production in major port activities worldwide. Because China operates several of the world’s largest container ports, the paper mainly explores the Chinese system itself but also provides important insights that could inform improvements elsewhere.
Identification of Common Paths for Rideshare Routing by Mining Vehicle Trajectories
Authors: Sun Danyang , Leurent Fabien
Published: July 2023

Trajectory data generated from various location sensors are increasingly available nowadays, providing comprehensive information on detailed itineraries that can be used in traffic and mobility analyses. This paper presents a study on the identification of underlying traffic stream clusters by exploring vehicle trajectory data. It aims to break down the spatial distribution of mobility flows and recognize the common paths according to which tentative rideshare routes could be set up. A step-by-step methodological framework, which includes map matching, measuring path similarity at the geometry level, trajectory clustering according to overlapping segments, locating trunk routes on the network, and classifying new trajectories on the identified routes, is proposed. An experiment has been conducted using trajectories collected in the real world. The results showed that different traffic streams with regard to direction and travel distance can be identified clearly. Overall, this study offers a comprehensive means of leveraging trajectory data to analyze itinerary patterns and make comparisons between trajectories. Compared with previous efforts, the proposed method is effective in distinguishing between traffic streams even with regard to bidirectional flows along the same route. In addition, it has the capacity to identify the common routes of underlying traffic streams instead of simply picking out single hot links or origin–destination pairs. This study is an example of data-driven research that uses digital trajectories to detect common path issues and offers detailed guidance on its application in this respect.
Post-Acute and Long-Term Care Leaders’ Perspectives on Leading During COVID-19
Authors: Lane Sandi J. , Liu Darren , Rados Robert
Published: July 2023

Post-acute and long-term care (PALTC) delivery is complex, and the COVID-19 pandemic created additional complexities. This qualitative study investigates how PALTC administrators responded to the pandemic, factors that impacted their leadership role and decision-making. Participants from North Carolina ( N = 15) and Pennsylvania ( N = 6) were interviewed using an interview guide containing open-ended questions. The results revealed three themes: (1) critical knowledge and competencies; (2) resources, supports and essential actions taken; and (3) psychosocial impact. The findings suggest communication and relationship building were the most useful competencies. Lack of staff was a primary stress point during and after the pandemic.
Oral vitamin D supplementation on the prevention of peritoneal dialysis-related peritonitis: A pilot randomised controlled trial
Authors: Zhang Yu-Hui , Xu Xiao , Pi Hai-Chen , Yang Zhi-Kai , Johnson David W , Dong Jie
Published: July 2023

Objective:

Peritoneal dialysis (PD)-related peritonitis is independently associated with low serum 25-hydroxy vitamin D [25(OH)D] levels. Our objective is to examine the feasibility of conducting a large, randomised controlled trial to determine the effects of vitamin D supplementation on the risk of PD-related peritonitis.

Design:

Pilot, prospective, open-label randomised controlled trial.

Setting:

Peking University First Hospital, China.

Participants:

Patients receiving PD who had recovered from a recent episode of peritonitis between 30 September 2017 and 28 May 2020.

Interventions:

Oral natural vitamin D supplementation (2000 IU per day) versus no vitamin D supplementation for 12 months.

Primary and secondary outcome measures:

Primary outcomes were feasibility (recruitment success, retention, adherence, safety) and fidelity (change in serum 25(OH)D level during follow-up) for a large, randomised controlled trial in the future to determine the effects of vitamin D on PD-related peritonitis. Secondary outcomes were time to peritonitis occurrence and outcome of subsequent peritonitis.

Results:

Overall, 60 among 151 patients were recruited (recruitment rate was 39.7%, 95% CI 31.9–47.5%, recruitment rate among eligible patients was 61.9%, 95% CI 52.2–71.5%). Retention and adherence rates were 100.0% (95% CI 100.0–100.0%) and 81.5% (95% CI 66.8–96.1%), respectively. During follow-up, serum 25(OH)D levels increased in the vitamin D (VD) group (from 19.25 ± 10.11 nmol/L to 60.27 ± 23.29 nmol/L after 6 months, p < 0.001, n = 31), and remained higher ( p < 0.001) than those in the control group ( n = 29). No differences were observed between the two groups with respect to time to subsequent peritonitis (hazard ratio 0.85, 95% CI 0.33–2.17) or any of the peritonitis outcomes. Adverse events were uncommon.

Conclusions:

A randomised controlled trial of the effect of vitamin D supplementation on peritonitis occurrence in patients receiving PD is feasible, safe and results in adequate serum 25(OH)D levels.
The role of higher education in sustainable creative careers: Exploring UK theatre graduates and theatre careers
Authors: de Bernard Manfredi , Comunian Roberta , Jewell Sarah , Salvador Elisa , O’Brien Dave
Published: July 2023

This paper reflects on the systematic interconnections between creative workers and higher education institutions (HEIs). Despite the latter representing key intermediaries in creative industries’ development and creative workers’ career trajectories, the relationship between the two has rarely been framed in a relational and systemic framework. To do so, we chose the UK theatre sector as the case study and adopted a mixed methodology: UK Higher Education Statistical Agency quantitative data, which informed us on the employment state of workers 6 months after graduation, were combined with 21 semi-structured interviews with actors and actresses to understand the complexity of their relationship with HEIs. HEIs emerge as the initial door to paid jobs and professional networks for graduates and as employers for those in the later stages of their careers: the lack of formal ways to access jobs and the precarious working conditions for performers make hence HEIs a crucial force in shaping workers’ careers. Furthermore, HE remains throughout the career of theatre workers an important part of their portfolio, providing reliable income and more stable working patterns when needed. The paper concludes with the findings’ policy implications and the future role of HEIs in creative and cultural ecosystems.
Robust real-time upper limb motion transfer from human to humanoid for manipulation skill teaching
Authors: Han Ke , Li Shiqi , Li Zhuo , Zhou Yumei , Fu Chunjiang , Xiong Youjun
Published: July 2023

This paper presents a framework for real-time high-fidelity upper limb motion transfer from a human to a humanoid robot, intending to provide robust support for robots to learn manipulation skills. Robot imitation of human motion is modeled as a simultaneous wrist and elbow tracking problem, where the coordination between multiple imitation objectives and physical constraints receives special attention. First, for the vision-based motion capture system, an efficient preprocessing method is introduced to map the raw human skeletal points analogously or reflectively to the robot’s workspace. Then, the generation of velocity-level imitation motion commands is formalized as a constrained hierarchical quadratic programing (HQP) problem, in which multiple objectives for achieving imitation are organized into a hierarchy. The wrist tracking task is set as the highest priority, followed by the adjustment of the elbow and the minimization of the joint velocity. Physical limits of the robot joints, as well as strict kinematic constraints regarding self-motion, are considered as constraints for the optimization problem. Finally, a hierarchical recurrent neural network (RNN) is designed to solve this HQP problem through its unique neural dynamics. The performance of this network is theoretically guaranteed with high computational efficiency. Quantitative results show that the proposed motion imitation control scheme offers excellent integrated tracking accuracy of [Formula: see text] m and is robust to different arm length ratios. Using this method, the humanoid robot can imitate the upper body motions of a human as accurately as possible under physical constraints, without significant delays.
Real-time vehicular fuel consumption estimation using machine learning and on-board diagnostics data
Authors: Abediasl Hamidreza , Ansari Amir , Hosseini Vahid , Koch Charles Robert , Shahbakhti Mahdi
Published: July 2023

Instantaneous fuel consumption estimation of fleet vehicles provides essential tools for fleet operation optimization and intelligent fleet management. This study aims to develop practical and accurate models to estimate instantaneous fuel consumption based on on-board diagnostics (OBD) data. Fuel consumption data is measured by a high-precision fuel flow meter. Two machine learning algorithms of Random Forest (RF) and Artificial Neural Networks (ANN) are trained with real-world urban and highway driving data of four fleet vehicles with different types and powertrain systems. In addition, the cold-start period of the vehicle operation is included to cover the fuel consumption penalty in the warm-up period. The validation results show that the RF method is more accurate than the ANN method, and both of the machine learning models have a better accuracy compared to the existing fuel consumption calculation methods based on the engine control unit (ECU) parameters.