bluuebunny/crossref_metadata_2025 huggingface dataset:
For debate: advanced bleeding control potentially saves lives in armed forces and should be considered
Authors: Borger van der Burg Boudewijn L S , Keijzers P , van Dongen T T C F , van Waes O J F , Hoencamp R
Published: June 2019

Introduction

Advanced bleeding control options for truncal and junctional haemorrhage including resuscitative endovascular balloon occlusion of the aorta (REBOA) have been used in managing catastrophic bleeding. The primary aim is to report on potential indications for advanced bleeding control in combat casualties during the Dutch deployment in Uruzgan, Afghanistan, between August 2006 and August 2010. The secondary aim is to report on training methods for advanced bleeding control in (para)medical personnel.

Methods

The trauma registry from the Dutch role 2 enhanced medical treatment facility at Tarin Kowt, Uruzgan, Afghanistan, was used to analyse patients who sustained a battle injury with major haemorrhage. Furthermore, a comprehensive search was performed on training (para)medical personnel in advanced bleeding control.

Results

There were 212 possible indications for advanced bleeding control with mortality of 28.8% (61/212). These possible indications consisted of 1.9% (4/212) junctional lower extremity injuries with a 75% (3/4) mortality rate, 59% (125/212) visceral vascular injuries with a mortality rate of 12.5% (26/125). The junctional and visceral injuries (n=129) were all potential indications for advanced bleeding control options, such as REBOA. Further 39.2% (83/212) casualties with central thoracic or neck injuries had a mortality rate of 38.6% (32/83). Based on an Abbreviated Injury Scale chest or abdomen score ≥461 indications for advanced bleeding control were identified. A 24-hour average of 8.8 packets of red blood cells, 4.2 packets of plasma and 1.9 packets of platelets was used to prevent exsanguination. The total out-of-hospital survival rate was 64% (39/61).

Conclusion

Retrospective analysis revealed 212 potential indications for advanced bleeding control with a mortality of 28.8% (61/212). Advanced bleeding control, such as REBOA, might have improved survival in approximately 61 of 212 casualties. Advanced bleeding control could be used as an adjunct to improve outcomes in major truncal or junctional haemorrhage in prehospital, remote settings and implementation should be considered. Vascular access training and REBOA placement for (para)medical military personnel should be explored in future research.
Deforming discontinuous groups for Heisenberg motion groups
Authors: Baklouti Ali , Bejar Souhail , Dhahri Khaireddine
Published: June 2019

We study in this paper the local rigidity proprieties of deformation parameters of the natural action of a discontinuous group [Formula: see text] acting on a homogeneous space [Formula: see text], where [Formula: see text] stands for a closed subgroup of the Heisenberg motion group [Formula: see text]. That is, the parameter space admits a locally rigid (equivalently a strongly locally rigid) point if and only if [Formula: see text] is finite. Moreover, Calabi–Markus’s phenomenon and the question of existence of compact Clifford–Klein forms are also studied.
Transport properties of an organic material under a temperature gradient
Authors: Tang Lijuan , Zhang Xinting , Yan Baoying , Liu Lei , Wang Changhu , Fu Qi , Yang Fujiang
Published: June 2019

Thermoelectric properties of organic materials have attracted much attention for the potential application in clean energy sources. In this work, we use the master equation method to calculate transport properties of the organic material when there is a temperature gradient in the material. The themoelectric property is analyzed with our model under different temperatures and different disorder strengths. It will be helpful to understand the thermoelectric property of organic materials and make good use of the heat energy.
A Condition-Based Maintenance Policy (CBM) of Repairable Multi-Component Deteriorating Systems Based on Quality Information
Authors: Ren Naifei , Wang Yu , Gan Shuyuan
Published: June 2019

The maintenance decision analysis of equipment has always been one of the hot spots of concern for researchers. A maintenance policy for parallel production systems is investigated in this study, with the parallel components having equal cost parameters. The rejection rate indicates the degradation degree of the machine, and the rejection rate is assumed to be obtained by detection. The maintenance strategy proposed in this paper involves two threshold values. By optimizing with genetic algorithm, the threshold values [Formula: see text] and [Formula: see text] corresponding to the minimum expected total cost can be found. Finally, the result of sensitivity analysis is shown that the cost parameter has a great influence on the threshold values.
Organic Functionalization of Mesoporous Silica Spheres as a Nanovehicle for DOX pH-Triggered Delivery
Authors: Wang Shuai , Song Fang Xiang , Zhang Li , Zhang Xue , Li Yan
Published: June 2019

Mesoporous silica (MS) spheres of different sizes with pH-responsive characteristics were synthesized based on Stöber’s theory. Organic functionalization with aminopropyl and carboxyl groups resulted in different materials, namely, MS@NH2@COOH. MS@NH2@COOH were observed to have a large number of carboxyl groups and multiamine chains, and were grafted into pore channels and pore outlets through systematic characterization analyses. All modified samples demonstrated the controlling of the delivery rate of DOX from the siliceous matrix. We also compared the drug release behavior of the DOX-loaded materials at high pH (7.4) and low pH (5.5) and studied the cytotoxicity on A549 cells. The experimental results indicated that the drug delivery system can better control drug release and have potential applications in the drug delivery field.
In situ Synthesis of p–n LaFeO3/ZnIn2S4 Heterojunctions for Enhanced Photocatalytic Activity
Authors: Gao Wen , Zhang Chengjia , Cui Sainan , Liang Qian , Xu Song , Li Zhongyu
Published: June 2019

In this study, LaFeO3/ZnIn2S4 composites were synthesized via in situ synthesis. The composition, structure and optical absorption properties of LaFeO3/ZnIn2S4 were characterized by X-ray diffraction (XRD), ultraviolet-visible diffuse reflectance spectroscopy, fluorescence spectroscopy (PL), Fourier Transform infrared spectroscopy (FT-IR) and field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The photocatalytic activity of the LaFeO3/ZnIn2S4 photocatalyst was determined based on the degradation of methyl orange (MO). LaFeO3/ZnIn2S4 composites showed much better photocatalytic performance compared with pure LaFeO3 and ZnIn2S4. The enhanced photocatalytic performance was attributed to intimately contacted interfaces and charge transfer channels which can effectively transfer and separate the photogenerated charge carriers.
Observing Exoplanets in the Near-Infrared from a High Altitude Balloon Platform
Authors: Nagler Peter C. , Edwards Billy , Kilpatrick Brian , Lewis Nikole K. , Maxted Pierre , Netterfield C. Barth , Parmentier Vivien , Pascale Enzo , Sarkar Subhajit , Tucker Gregory S. , Waldmann Ingo
Published: June 2019

Although there exists a large sample of known exoplanets, little data exists that can be used to study their global atmospheric properties. This deficiency can be addressed by performing phase-resolved spectroscopy — continuous spectroscopic observations of a planet’s entire orbit about its host star — of transiting exoplanets. Planets with characteristics suitable for atmospheric characterization have orbits of several days, thus phase curve observations are highly resource intensive, especially for shared use facilities. In this work, we show that an infrared spectrograph operating from a high altitude balloon platform can perform phase-resolved spectroscopy of hot Jupiter-type exoplanets with performance comparable to a space-based telescope. Using the EXoplanet Climate Infrared TElescope (EXCITE) experiment as an example, we quantify the impact of the most important systematic effects that we expect to encounter from a balloon platform. We show an instrument like EXCITE will have the stability and sensitivity to significantly advance our understanding of exoplanet atmospheres. Such an instrument will both complement and serve as a critical bridge between current and future space-based near-infrared spectroscopic instruments.
Shellability is NP-complete
Authors: Goaoc Xavier , Paták Pavel , Patáková Zuzana , Tancer Martin , Wagner Uli
Published: June 2019

We prove that for every
d
≥ 2, deciding if a pure,
d
-dimensional, simplicial complex is shellable is NP-hard, hence NP-complete. This resolves a question raised, e.g., by Danaraj and Klee in 1978. Our reduction also yields that for every
d
≥ 2 and
k
≥ 0, deciding if a pure,
d
-dimensional, simplicial complex is
k
-decomposable is NP-hard. For
d
≥ 3, both problems remain NP-hard when restricted to contractible pure
d
-dimensional complexes. Another simple corollary of our result is that it is NP-hard to decide whether a given poset is CL-shellable.
Macrophages and T cells in atherosclerosis: a translational perspective
Authors: Bartlett Benjamin , Ludewick Herbert P. , Misra Ashish , Lee Silvia , Dwivedi Girish
Published: June 2019

Atherosclerosis is now considered a chronic maladaptive inflammatory disease. The hallmark feature in both human and murine disease is atherosclerotic plaques. Macrophages and various T-cell lineages play a crucial role in atherosclerotic plaque establishment and disease progression. Humans and mice share many of the same processes that occur within atherogenesis. The various similarities enable considerable insight into disease mechanisms and those which contribute to cardiovascular complications. The apolipoprotein E-null and low-density lipoprotein receptor-null mice have served as the foundation for further immunological pathway manipulation to identify pro- and antiatherogenic pathways in attempt to reveal more novel therapeutic targets. In this review, we provide a translational perspective and discuss the roles of macrophages and various T-cell lineages in contrasting proatherosclerotic and atheroprotective settings.
Mechanisms Underlying the Prevention and Treatment of Cholelithiasis Using Traditional Chinese Medicine
Authors: Chen Qiliang , Zhang Yuanyuan , Li Shunan , Chen Shujiao , Lin Xuejuan , Li Candong , Asakawa Tetsuya
Published: June 2019

Cholelithiasis is a major public health concern that necessitates highly effective, feasible, and recurrence-preventing therapies. Currently available surgical treatments and medications cannot effectively avoid the recurrence of cholelithiasis. Hence, several Chinese herbal compounds (CHCs) are considered for the treatment of cholelithiasis, considering that they can effectively discharge gallstones and prevent the recurrence of such condition. In the present narrative review, we aim to summarize the underlying mechanisms of currently used CHCs in the treatment of cholelithiasis and to describe the current situation of traditional Chinese medicine (TCM) use for cholelithiasis. Several commonly used CHCs were used to illustrate these issues. We found that the mechanisms underlying the CHC treatments rely on the amelioration of the biliary dynamics factors, maintenance and protection of the liver function, reduction of the cholesterol and bilirubin levels, and regulation of the inflammatory reactions. CHCs as treatments based on TCM can ameliorate the overall bodily function, thereby preventing the recurrence of cholelithiasis. Appropriate application of CHCs would be beneficial for patients and clinicians, although the safety and efficacy of CHCs need further verification.
1D Confocal Broad Area Semiconductor Lasers (Confocal BALs) for Fundamental Transverse Mode Selection (TMS#0)
Authors: Fouckhardt Henning , Kleinschmidt Ann-Kathrin , Strassner Johannes , Doering Christoph
Published: June 2019

Previously in this journal we have reported on fundamental transverse mode selection (TMS#0) of broad area semiconductor lasers (BALs) with integrated twice-retracted 4f set-up and film-waveguide lens as the Fourier-transform element. Now we choose and report on a simpler approach for BAL-TMS#0, i.e., the use of a stable confocal longitudinal BAL resonator of length L with a transverse constriction. The absolute value of the radius R of curvature of both mirror-facets convex in one dimension (1D) is R = L = 2f with focal length f. The round trip length 2L = 4f again makes up for a Fourier-optical 4f set-up and the constriction resulting in a resonator-internal beam waist stands for a Fourier-optical low-pass spatial frequency filter. Good TMS#0 is achieved, as long as the constriction is tight enough, but filamentation is not completely suppressed.
Kinetics, Isotherm, Thermodynamics, and Recyclability of Exfoliated Graphene-Decorated MnFe2O4 Nanocomposite Towards Congo Red Dye
Authors: Pham Van Thinh , Nguyen Hong-Tham T. , Tran Thuan Van , Nguyen Duyen Thi Cam , Le Hanh T. N. , Nguyen Thuong Thi , Vo Dai-Viet N. , Le Thi Hong Nhan , Nguyen Duy Chinh
Published: June 2019

Herein, we described the use of exfoliated graphene- (EG-) decorated magnetic MnFe2O4 nanocomposite (EG@MnFe2O4) for the removal and adsorption of Congo red (CR) dye from wastewater. Firstly, the precursors (EG, MnFe2O4) and EG@MnFe2O4 were fabricated, characterized using several physical analytical techniques such as X-ray powder diffraction (XRD), scanning electron microscope (SEM), transmission electron microscopy (TEM), and N2adsorption/desorption isotherm measurement. For the adsorption experiments, the effect of contact time (0–240 min), concentration (10–60 mg/L), solution pH (2–10), adsorbent dosage (0.03–0.07 g), and temperature (283–313 K) was rigorously studied. To elucidate the adsorption mechanism and behaviour of CR over EG@MnFe2O4 and MnFe2O4 adsorbents, the kinetic models (pseudo-first-order, pseudo-second-order, Elovich, and Bangham) and isotherm models (Langmuir, Freundlich, Temkin, and Dubinin–Radushkevich) have been adopted. The kinetic results indicated that models adhered to the pseudo-second-order equation, exhibiting the chemisorption mechanism in heterogeneous phrase. Meanwhile, the isotherm results revealed the adsorption of CR over EG@MnFe2O4 obeyed the monolayer behaviour (Langmuir model) rather than multilayer behaviour (Freundlich equation) over MnFe2O4. The thermodynamic study also suggested that such adsorption was an endothermic and spontaneous process. With high maximum adsorption capacity (71.79 mg/g) and good recyclability (at least 4 times), EG@MnFe2O4 can be a potential alternative for the adsorptive removal of CR dye from water.
Effects of Controlled Atmosphere on the Storage Quality and Aroma Compounds of Lemon Fruits Using the Designed Automatic Control Apparatus
Authors: Ma Yuan , Li Shaohua , Yin Xiaocui , Xing Yage , Lin Hongbin , Xu Qinglian , Bi Xiufang , Chen Cunkun
Published: June 2019

‘Eureka’ lemon fruits were stored under four controlled atmosphere- (CA-) combinations at 8°C for 20 days to investigate the effects on weight loss (WL), total soluble solids (TSS), titratable acidity (TA), vitamin C (VC), total phenolic content (TPC), sodium carbonate-soluble pectin (SSP), malondialdehyde (MDA), and volatile compounds. Results showed that the contents of TSS, TA, VC, and SSP in the stored fruits reduced during the storage period, while the WL and MDA increased. Fruit stored under CA2-combination (6 % O2+8 % CO2) showed the lower contents of WL and MDA and the higher content of TSS, TA, TPC, and VC than that of other treated fruits. The main volatile compounds present in the lemons were terpenoids, aldehydes, alcohols, and esters. In addition, both the terpenoid and aldehyde content are substantially higher in lemons exposed to CA2 conditions. In contrast, the alcohols and esters displayed elevated levels in the regular air (RA) stored fruit. In conclusion, CA with the suitable conditions proves to be better than RA as a storage regimen to keep the quality of lemons. These results indicated that the application of 6% O2+8% CO2 CA conditions could maintain the quality of ‘Eureka’ lemon fruit during the storage time of 20 days and should be the optimal storage environment for postharvest Eureka lemons.
Melanotic Schwannoma of the Vagina: A Report of a Very Rare Tumor and Review of the Literature
Authors: Effah Kofi , Seidl Stefan , Gorges Edith , Akakpo Patrick Kafui
Published: June 2019

Melanotic schwannoma (MS) is a rare nerve sheath tumor with fewer than 200 cases reported. MS has uncertain malignant potential and comprises 1% of all nerve sheath tumors with a predilection for the spinal nerve roots. An even rarer location for this tumor is the vagina. Up to 55% of MSs that contain psammoma bodies are associated with the Carney complex, an autosomal dominant syndrome. Criteria for malignancy in MS are still not well established and long term follow-up of patients is recommended. A 26-year-old woman presented with a bleeding vaginal tumor which was diagnosed as MS following excision. The clinical, histopathological, and immunohistochemical features of this tumor are discussed.
Thermal Effects Associated with RF Exposures in Diagnostic MRI: Overview of Existing and Emerging Concepts of Protection
Authors: van den Brink Johan S.
Published: June 2019

Apart from magnetic attraction risks, the primary biophysical concern associated with MRI is radiofrequency heating of the human body and associated discomfort, health deterioration, or potential burns. This paper reviews experimental data and numerical modeling of systemic (core and brain) temperature and local thermal effects associated with diagnostic MRI exposures at 1.5T (64 MHz) and 3.0T (128 MHz). Allowable temperatures and duration of systemic exposure are established based on knowledge of (short-term) human thermobiology. Longer term effects related to DNA damage or altered cellular pathways are not covered in this review. Updated limits are proposed for core temperature increase (≤1.3°C) and for Specific Absorption (<4 kJ/kg). The potential use of thermal dose (CEM43) for local thermal protection is described, and previously proposed exposure limit values are evaluated against available data from current MRI practice. Gaps in knowledge are identified, and recommendations for additional research are provided.
Disruption of Long Noncoding RNAs Targets Cancer Hallmark Pathways in Lung Tumorigenesis
Authors: Davalos Veronica , Esteller Manel
Published: June 2019

Advances in high-throughput genomic and epigenomic technologies have revealed the tremendous complexity of the transcriptional landscape. Beyond protein-coding RNAs (derived from only ∼1.5% of the genome), noncoding RNAs (ncRNA) are emerging as versatile key regulators of gene information involved in multiple major biological processes. Accordingly, deregulation of ncRNA expression has been associated with multiple diseases, including cancer. In this issue of Cancer Research, Shahabi and colleagues characterize LINC00261 as a tumor suppressor long ncRNA epigenetically silenced in lung cancer. They provide crucial mechanistic insights to explain its role in lung tumorigenesis, demonstrating that deregulation of the LINC00261/FOXA2 locus disrupts DNA damage repair signaling, cell-cycle control, and cell proliferation.

See related article by Shahabi et al., p. 3050
Prediction of cutting and feed forces for conventional milling process using adaptive neuro fuzzy inference system (ANFIS)
Authors: Nayak Kanhu Charan , Tripathy Rajesh Kumar , Panda Sudha Rani , Sahoo Shiba Narayan
Published: June 2019

Due to the extensive use of highly automated machine tools in the industry, the manufacturing requires reliable models for the prediction of output performance of machining processes. The prediction of cutting forces plays an important role in the manufacturing industry. The focus of this paper is to develop a reliable method to predict cutting forces (force in X-direction and force in Z-direction) for milling process during conventional machining of mild steel. This paper implements an adoptive Neuro-fuzzy interface system (ANFIS) to actualize an efficient model for prediction of cutting forces during conventional milling. A set of three input machining parameters like speed, feed and depth of cut, which has a major impact on the cutting forces was chosen as input to represent the machining condition. Our result confirms that ANFIS model with Gaussian member function is a better predictive tool for prediction of milling forces with minimum average test error.
Prediction of Daily Network Traffic based on Radial Basis Function Neural Network
Authors: Haviluddin Haviluddin , Tahyudin Imam
Published: June 2019

This paper presents an approach for predicting daily network traffic using artificial neural networks (ANN), namely radial basis function neural network (RBFNN) method. The data is gained from 21 – 24 June 2013 (192 samples series data) in ICT Unit Universitas Mulawarman, East Kalimantan, Indonesia. The results of measurement are using statistical analysis, e.g. sum of square error (SSE), mean of square error (MSE), mean of percentage error (MPE), mean of absolute percentage error (MAPE), and mean of absolute deviation (MAD). The results show that values are the same, with different goals that have been set are 0.001, 0.002, and 0.003, and spread 200. The smallest MSE value indicates a good method for accuracy. Therefore, the RBFNN model illustrates the proposed best model to predict daily network traffic.
Offline Signature Verification and Forgery Detection Based on Computer Vision and Fuzzy Logic
Authors: Prakash Gautam S. , Sharma Shanu
Published: June 2019

Automated signature verification and forgery detection has many applications in the field of Bank-cheque processing,document  authentication, ATM access etc. Handwritten signatures have proved to be important in authenticating a person's identity, who is signing the document. In this paper a Fuzzy Logic and Artificial Neural Network Based Off-line Signature Verification and Forgery Detection System is presented. As there are unique and important variations in the feature elements of each signature, so in order to match a particular signature with the database, the structural parameters of the signatures along with the local variations in the signature characteristics are used. These characteristics have been used to train the artificial neural network. The system uses the features extracted from the signatures such as centroid, height – width ratio, total area, Ist and IInd order derivatives, quadrant areas etc. After the verification of the signature the angle features are used in fuzzy logic based system for forgery detection.
A Fuzzy Controller for Compensation of Voltage Sag/Swell Problems Using Reduced Rating Dynamic Voltage Restorer
Authors: Damaraju Rajesh , Lalitha S.V.N.L.
Published: June 2019

Non linear loads are highly effected by variations in voltages. Dynamic voltage restorer is one of the most popular compensating devices due to its low cost and better performance. Usage of Park’s transformation technique effectively reduces the rating of Dynamic voltage restorer. Application of fuzzy logic controller for getting the better result is proposed in this paper. The results are verified in Matlab/Simulink environment.
Fuzzy Logic Controller for Cascaded H-Bridge Multilevel Inverter
Authors: Sivakumar N. , Sumathi A.
Published: June 2019

This paper proposes fuzzy logic controller based seven-level hybrid inverter for photovoltaic systems with sinusoidal pulse width-modulation (SPWM) techniques. Multi-Level Inverter technology have been developed in the area of high-power medium-voltage energy scheme, because of their advantages such as devices of high dv/dt rating, higher switching frequency, unlimited power processing, shape of output waveform and desired level of output voltage, current and frequency adjustment.This topology can be used there by enabling the scheme to reduce the Total Harmonic Distortion (THD) for high voltage applications. The Maximum Power Point Tracking algorithm is also used for extracting maximum power from the PV array connected to each DC link voltage level. The Maximum Power Point Tracking algorithm is solved by Perturb and Observer method.It has high performance with low Total Harmonic Distortion and reduced by this control strategy. The proposed system has verified and THD is obtained by using MATLAB/simulink.The result is compared with the hardware prototype working model.
Conventional DC Voltage Operating System for High Speeed Traction Power Supplies Using LLC-HPQC Control
Authors: Babu Ch. Lenin , Reddy P. Harinath , Sekhar T. Reddi
Published: June 2019

In this paper a hybrid power quality compensator (HPQC) is proposed for compensation in cophase traction power supply and minimum dc operation voltage is achievable for high-speed traction power supply. The parameter design procedure for minimum dc operation voltage in HPQC as well as minimum voltage rating with load PF is discussed. The detailed discussions of proposed circuit configurations of HPQC are provided in section II, together with comparison with conventional RPC. In comparison with conventional railway power compensator proposed HPQC can achieve reduced dc link voltage level. It is also verified through simulations results that the LLC-HPQC would operate at the minimum voltage with the proposed parameter design. HPQC is able to provide system unbalances, reactive power, and harmonic compensation in cophase traction power with reduced operation voltage. The cophase traction power supply with proposed HPQC is suitable for high-speed traction applications.
Multi-agent System for Documents Retrieval and Evaluation Using Fuzzy Inference Systems
Authors: Ivanova Galina , Andreev Ark , Shouman Marwa A.
Published: June 2019

Recently the World Wide Web are packed with huge quantities of information. From this view the user finds it difficult to get the relevant informations due to the increased of their quantities. This paper uses multi-agent system uses intelligent agent in order to retrieval documents from the World Wide Web. The user by this system can easily get the relevant documents which to need them.Multi-agent System is combined with fuzzy inference system for ranking documents. The documents ranking score by cosine similarity using fuzzy inference system development and implemented much simpler than the traditional method which require mathematical equations.
Shrinkage of Real Power Loss by Enriched Brain Storm Optimization Algorithm
Authors: Kanagasabai Lenin
Published: June 2019

This paper proposes Enriched Brain Storm Optimization (EBSO) algorithm is used for soving reactive power problem. Human being are the most intellectual creature in this world. Unsurprisingly, optimization algorithm stimulated by human being inspired problem solving procedure should be advanced than the optimization algorithms enthused by collective deeds of ants, bee, etc. In this paper, we commence a new Enriched brain storm optimization algorithm, which was enthused by the human brainstorming course of action. In the projected Enriched Brain Storm Optimization (EBSO) algorithm, the vibrant clustering strategy is used to perk up the k-means clustering process. The most important view of the vibrant clustering strategy is that; regularly execute the k-means clustering after a definite number of generations, so that the swapping of information wrap all ideas in the clusters to accomplish suitable searching capability. This new approach leads to wonderful results with little computational efforts. In order to evaluate the efficiency of the proposed Enriched Brain Storm Optimization (EBSO) algorithm, has been tested standard IEEE 118 & practical 191 bus test systems and compared to other standard reported algorithms. Simulation results show that Enriched Brain Storm Optimization (EBSO) algorithm is superior to other algorithms in reducing the real power loss.
Distance Weighted K-Means Algorithm for Center Selection in Training Radial Basis Function Networks
Authors: Aik Lim Eng , Hong Tan Wei , Junoh Ahmad Kadri
Published: June 2019

The accuracies rates of the neural networks mainly depend on the selection of the correct data centers. The K-means algorithm is a widely used clustering algorithm in various disciplines for centers selection. However, the method is known for its sensitivity to initial centers selection. It suffers not only from a high dependency on the algorithm's initial centers selection but, also from data points. The performance of K-means has been enhanced from different perspectives, including centroid initialization problem over the years. Unfortunately, the solution does not provide a good trade-off between quality and efficiency of the centers produces by the algorithm. To solve this problem, a new method to find the initial centers and improve the sensitivity to the initial centers of K-means algorithm is proposed. This paper presented a training algorithm for the radial basis function network (RBFN) using improved K-means (KM) algorithm, which is the modified version of KM algorithm based on distance-weighted adjustment for each centers, known as distance-weighted K-means (DWKM) algorithm. The proposed training algorithm, which uses DWKM algorithm select centers for training RBFN obtained better accuracy in predictions and reduced network architecture compared to the standard RBFN. The proposed training algorithm was implemented in MATLAB environment; hence, the new network was undergoing a hybrid learning process. The network called DWKM-RBFN was tested against the standard RBFN in predictions. The experimental models were tested on four literatures nonlinear function and four real-world application problems, particularly in Air pollutant problem, Biochemical Oxygen Demand (BOD) problem, Phytoplankton problem, and forex pair EURUSD. The results are compared to proposed method for root mean square error (RMSE) in radial basis function network (RBFN). The proposed method yielded a promising result with an average improvement percentage more than 50 percent in RMSE.
On the Oxypoda species of Turkey and adjacent regions. II. Three new species, additional records, and a checklist (Coleoptera: Staphylinidae, Aleocharinae)
Authors: ASSING VOLKER
Published: June 2019

Three species of Oxypoda Mannerheim from Turkey are described and illustrated: O. (Podoxya) pontica sp. n. (Rize), O. (Bessopora) aydinica sp. n. (Aydın), and O. (Mycetodrepa) obscuricollis sp. n. (Mersin). A new combination and a new synonymy are established: Oxypoda (Thliboptera) scheerpeltziana (Fagel, 1968), comb. n. (ex Aleochara) = Oxypoda micantoides Assing, 2006, syn. n. Additional records of previously described species are reported from Turkey (22 species), Lebanon (1 species), and Israel (1 species), among them the first Turkish records of O. brevicornis (Stephens), O. lesbia Assing, and O. recondita Kraatz, as well as the first record of O. ignorata Zerche from Lebanon. The distributions of 10 species are mapped. A checklist of all Oxypoda species reported from Turkey is compiled.
On the Aploderus species of Turkey (Coleoptera: Staphylinidae, Oxytelinae)
Authors: ASSING VOLKER
Published: June 2019

Two microphthalmous species of Aploderus Stephens from Turkey are described, illustrated, and distinguished from their closest relative, A. schweigeri (Smetana): A. magniceps sp. n. and A. capitulatus sp. n. Their distributions are mapped. The first record of A. endogaeus Assing since its original description is reported; the previously unknown male sexual characters of this species are illustrated. A key to the Western Palaearctic species of the genus is provided.
The Mesoamerican Mesorhaga (Diptera: Dolichopodidae), with a taxonomic conspectus of the New World fauna
Authors: BICKEL DANIEL J.
Published: June 2019

The Mesoamerican Mesorhaga Schiner are revised, illustrated and keyed, and include twelve species, ten of them newly described: Mesorhaga lacrymans Parent (Costa Rica and Panama), M. cocori n. sp., M. hule n. sp., M. sarukhani n. sp., M. baadsvicki n. sp., M. villanuevi n. sp. (all Costa Rica), M. isthmia n. sp. (Costa Rica, Panama, Nicaragua, El Salvador, and Mexico), M. adunca (Van Duzee) (Guatemala), M. mexicana n. sp., M. falciunguis n. sp., M. minatitlan n. sp., and M. nayaritensis n. sp. (all Mexico). A checklist of the New World Mesorhaga fauna is provided along with notes on selected species. M funebris Parent from the tropical Andes is redescribed and the male postabodomen of M. caudata Van Duzee from Georgia, U.S.A. is illustrated.
A new European species of Delia Robineau-Desvoidy (Diptera: Anthomyiidae) near the wheat bulb fly, D. coarctata (Fallén)
Authors: MICHELSEN VERNER
Published: June 2019

A new species of Delia Robineau-Desvoidy is described from Europe (Denmark, Sweden, Finland and Czech Republic) by the name of D. coarctoides. It is very similar to and has been confused with the wheat bulb fly, D. coarctata (Fallén), a well known anthomyiid pest species of cereals and grasses in Europe. A brief overview of the D. coarctata species group and a key to males and females are given.
Two new genera in the Nymphidiina (Lepidoptera: Riodinidae: Nymphidiini)
Authors: HALL JASON P. W.
Published: June 2019

Two new riodinid genera in the subtribe Nymphidiina (tribe Nymphidiini) are described from the lowlands of the Amazon basin. Livendula Hall, n. gen., is described with huebneri Butler as its type species, and the following eleven species are transferred to Livendula (n. combs.) from Adelotypa Warren: amasis Hewitson, aminias Hewitson, aristus Stoll, balista Hewitson, epixanthe Stichel, huebneri Butler, jasonhalli Brévignon & Gallard, leucocyana Geyer, leucophaea Hübner, pauxilla Stichel, and violacea Butler. Minotauros Hall, n. gen., is described with lampros Bates as its type species, and the following two species are transferred to Minotauros (n. combs.) from Adelotypa: lampros Bates, and charessa Stichel.
The karyotype of Blarinomys breviceps (Mammalia: Rodentia: Cricetidae) with comments on its morphology and some ecological notes
Authors: GEISE LENA , BERGALLO HELENA G. , ESBÉRARD CARLOS E. L. , ROCHA CARLOS F. D. , VAN SLUYS MONIQUE
Published: June 2019

The geographic distribution of Blarinomys breviceps (Winge) includes few localities in forested areas in the Atlantic Rainforest from Bahia state in Brazil up to Misiones province in Argentina. Here we add 14 new records for the species in the region of southeastern Brazil. These findings provided information on morphology, natural history and the first karyological data for the species. During two short surveys, one in Santuário da Serra da Concórdia, Valença municipality and another in Fazenda Marimbondo, Mauá municipality, Rio de Janeiro State, Brazil, six specimens were collected in pit fall traps. The specimen trapped in Serra da Concórdia was a sub adult male (age class 3 according to the upper molar row wear). In Fazenda Marimbondo, four adult males and one adult female were captured. Serra da Concórdia is a secondary vegetation in a semideciduous forest type, being a small fragment of 220 ha. The second locality, Fazenda Marimbondo is a high montane forest in an evergreen forest type. Karyotype of the specimen collected in the first locality presented a diploid number of 28 chromosomes and an autosomal number of 50. The specimen collected in Serra da Concórdia was kept alive for seven days. During this period it was fed with live arthropods, what confirms their insectivorous feeding habit, consistent with the molar teeth morphology.
A new species of marsupial frog of the genus Gastrotheca Fitzinger (Anura: Amphignatodontidae) from the State of Bahia, Northeastern Brazil
Authors: JUNCÁ FLORA ACUÑA , NUNES IVAN
Published: June 2019

A new species of Gastrotheca is described from Serra da Jibóia, Municipality of Santa Terezinha, State of Bahia, Northeastern Brazil. Gastrotheca flamma sp. nov. is characterized by the following combination of traits: SVL 55.3 mm; skin on dorsum weakly granulate; skin adherent on head; snout truncate in dorsal view and nearly vertical in profile; tympanum rounded; presence of two small supraocular tubercles (anterior tubercle bigger than posterior one); webbing poorly developed between fingers II-III and III-IV; calcars present; distinct color pattern. Comments on species habitat are provided.
The Campsicnemus lobatus and zigzag groups in the Society Islands, French Polynesia (Diptera: Dolichopodidae)
Authors: EVENHUIS NEAL L.
Published: June 2019

The genus Campsicnemus is recorded for the first time from the Society Islands in French Polynesia. Two endemic species groups are recognized: the lobatus group (5 new species) and the zigzag group (5 new species) and keys given to species within them. The following 10 new species are described and illustrated: Campsicnemus borabora Evenhuis, n. sp. (Bora Bora); C. lobatus Evenhuis, n. sp. (Moorea); C. mylloseta Evenhuis, n. sp. (Huahine); C. ogradyi Evenhuis, n. sp. (Tahiti); C. ostlinx Evenhuis, n. sp. (Raiatea); C. paralobatus Evenhuis, n. sp. (Tahiti); C. rheocrenus Evenhuis, n. sp. (Tahiti); C. tahaanus Evenhuis, n. sp. (Tahaa); C. tunoa Evenhuis, n. sp. (Moorea); and C. zigzag Evenhuis, n. sp. (Tahiti).
Synopsis of Prosierola (Hymenoptera: Bethylidae)
Authors: AZEVEDO CELSO O.
Published: June 2019

The identity of many species of Prosierola is currently unknown, mostly because the available taxonomic information is not sufficiently accurate to allow for precise identifications. To solve this problem, nine valid species were investigated. Neotropical species of Bethylinae were also examined in order to find possible misclassified species of Prosierola. In this paper six nomenclatural changes are made, and six valid species recognized. The lectotype of Parasierola flavicoxis Kieffer is designated. The following new species-group synonyms are established: Prosierola lata (Cameron) syn. nov. for Prosierola nasalis (Westwood); Prosierola insularis Evans syn. nov. for Prosierola cubana Evans, and Prosierola bicarinata (Brues) syn. nov. for Prosierola flavicoxis (Kieffer), and Prosierola variegata Evans syn. nov. for Prosierola obliqua Evans. The following new combination is established: Prosierola flavicoxis (Kieffer) from Goniozus.
The species of the genus Athousius Reitter, 1905 of China, and re-establishment of the genus Thacana Fleutiaux, 1936 (Insecta: Coleoptera, Elateridae)
Authors: SCHIMMEL RAINER , TARNAWSKI DARIUSZ
Published: June 2019

The species of the genus Athousius Reitter, 1905 from China are revised, described, illustrated, a key to species is given, and some systematic characters are discussed. The genus Thacana Fleutiaux, 1936 is re-established as a bona gen. and is excluded from the Chinese fauna in this paper. The following species are introduced as new to science: Athousius gansuensis sp. n., A. jiuzhaigonensis sp. n., A. muyupingensis sp. n., and A. shaanxiensis sp. n.
Contribution to the knowledge of Seychellois Scirtidae (Coleoptera: Scirtoidea)
Authors: RUTA RAFAŁ
Published: June 2019

Scirtes confinis sp. nov., S. flavohumeralis sp. nov., and S. mahensis sp. nov. are described from the Seychelles Archipelago. Cyphon circumductus Champion, 1924 is synonymized with C. insularius Champion, 1924. Cyphon insularius Champion, 1924, C. biperforatus Champion, 1924, C. mahensis Champion, 1924, and Scirtes seychellensis Champion, 1924 are redescribed and illustrated; lectotypes and paralectotypes of C. insularius and S. seychellensis are designated.
Description of a new species of Andaeschna (Odonata: Aeshnidae) from the Western Colombian Andes
Authors: BOTA-SIERRA CORNELIO ANDRÉS , SANDOVAL-H JULIANA , PALACINO-RODRÍGUEZ FREDY
Published: June 2019

Andaeschna is a small and poorly known genus of dragonflies that inhabits the Andes, from Venezuela to northwestern Argentina. Here we describe Andaeschna occidentalis sp. nov., first species of the genus recorded in the Western Andes, specifically from the Tatamá National Park in Colombia. Males of this species can be differentiated from the other four species in the genus by the unique shape of the distal segment of the vesica spermalis. Likewise, females can be distinguished by their smaller and broader cerci (slightly shorter than S9) and its subquadrate point. The discovery of this beautiful species expands the range of the genus, previously known only in the Eastern Andes.
Redescription of the paedomorphic goby Schindleria nigropunctata Fricke
& El-Regal 2017 (Teleostei: Gobiidae) from the Red Sea
Authors: AHNELT HARALD
Published: June 2019

Schindler’s fishes (Schindleria) are extremely paedomorphic and only a few morphological characters are suitable for species delimitation of these tiny fishes. Three of these key morphological characters, the (i) origin of the dorsal fin relative to the anal fin, (ii) number of vertebrae and (iii) coloration, need reinterpretation in a recently described species, Schindleria nigropunctata. To avoid nomenclatorial problems S. nigropunctata is redescribed from the type material. This species is characterized by 16–17 dorsal fin rays, 16 pectoral fin rays, origin of the anal fin ventral to the 8th dorsal fin ray, 37–38 myomeres, a uniform greyish-white colored body (preserved) and a trunk without obvious pigmentation (no black pigment spots). The eyes are dark grey with a silvery cornea. Dorsally on the cornea are blackish melanophores arranged in a sickle-shaped pattern.
[ARTICLE WITHDRAWN] AbCD133 Modified αCT1 Loaded Target Magnetic Mesoporous Silica Nano-Drugcarriers Can Sensitizes Glioma Cancer Stem Cells to TMZ and Have Therapeutic Potential on TMZ Resistant Glioblastoma
Authors: Xingyi Jin , Guonan Chi , Xin Zhao , Naijie Liu
Published: June 2019

THIS ARTICLE WAS WITHDRAWN BY THE AUTHORS IN JUNE 2020.
Stitching of depth and color images from multiple RGB-D sensors for extended field of view
Authors: Ding Changquan , Liu Hang , Li Hengyu
Published: June 2019

Existing commodity RGB-D sensors have a limited field of view compared with a nearly 360° horizontal field of view of Lidar. This article presents a method to extend the field of view by stitching depth and color images from multiple RGB-D sensors to form a depth and a color panorama. Firstly, a set of 3-D matched key points are constructed based on 2-D matched key points and corresponding depth values to estimate transformation matrices between multiple RGB-D sensors. Then, depth and color images are projected to the 3-D space using estimated transformation matrices to construct textured 3-D points. Finally, projecting textured 3-D points to a compositing surface can create the depth panorama and the color panorama. Experiments validated the accuracy and efficiency of the proposed method.
What encourages care workers to continue working in intellectual disability services in England? Interview findings
Authors: Stevens Martin , Moriarty Jo , Manthorpe Jill , Harris Jess , Hussein Shereen , Cornes Michelle
Published: June 2019

The article reports research aimed at identifying factors relating to retention in English intellectual disability services, drawing on a study of the social care workforce. The research involved two rounds of interviews with social care managers and staff between 2009 and 2014. The study uses social exchange theory, particularly the idea of ‘reciprocity’ and the mechanism of ‘hope’, as a conceptual framework to aid interpretation of the themes relating to retention identified in the interview analysis: ‘pay’, ‘support’, ‘morale’, and ‘training’ (related to reciprocity) and ‘improving quality of life’ and ‘supporting personal development’ (related to hope). Both groups of themes are identified as being particularly appropriate to intellectual disability services. The study concludes that reciprocity and hope seem to interact in factors related to staff retention, although the study suggests that reciprocity rather than hope is directly connected with retention.
Reducing Hospitalizations: Institution of Outpatient Infusional EPOCH-Based Chemotherapy at a Safety Net Hospital
Authors: Keshvani Neil , Hon Mary , Gupta Arjun , Brown Timothy J. , Roy Lonnie , Marley Eileen , Lindsey Sandy , Johnson David H. , Sadeghi Navid , Li Hsiao C.
Published: June 2019

PURPOSE:

EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin) -based chemotherapy is traditionally administered inpatient because of its complex 96-hour protocol and number of involved medications. These routine admissions are costly, disruptive, and isolating to patients. Here, we describe our experience transitioning from inpatient to outpatient ambulatory EPOCH-based chemotherapy in a safety-net hospital, associated cost savings, and patient perceptions.

METHODS AND MATERIALS:

Guidelines for chemotherapy administration and educational materials were developed by a multidisciplinary team of physicians, nurses, and pharmacists. Data were collected via chart review and costs via the finance department. Patient satisfaction with chemotherapy at home compared with hospitalization was measured on a Likert-type scale via direct-to-patient survey.

RESULTS:

From January 30, 2017, through January 30, 2018, 87 cycles of EPOCH-based chemotherapy were administered to 23 patients. Sixty-one ambulatory cycles (70%) were administered to 18 patients. Of 26 cycles administered in the hospital, 18 (69%) were the first cycle of treatment. Rates of inappropriate prophylactic antimicrobial prescription and laboratory testing were lower in the outpatient setting. Eight of nine patients surveyed preferred home chemotherapy to inpatient chemotherapy. Per-cycle drug costs were 57.6% lower in outpatients as a result of differences in the acquisition cost in the outpatient setting. In total, the transition to ambulatory EPOCH-based chemotherapy yielded 1-year savings of $502,030 and an estimated 336 days of avoided hospital confinement.

CONCLUSION:

Multiday ambulatory EPOCH-based regimens were successfully and safely administered in our safety-net hospital. Outpatient therapy was associated with significant savings through avoided hospitalizations and reductions in drug acquisition cost and improved patient satisfaction.
USP8 Deubiquitinates the Leptin Receptor and Is Necessary for Leptin-Mediated Synapse Formation
Authors: Bland Tyler , Sahin Gulcan Semra , Zhu Mingyan , Dillon Crystal , Impey Soren , Appleyard Suzanne M , Wayman Gary A
Published: June 2019

Leptin has neurotrophic actions in the hippocampus to increase synapse formation and stimulate neuronal plasticity. Leptin also enhances cognition and has antidepressive and anxiolytic-like effects, two hippocampal-dependent behaviors. In contrast, mice lacking leptin or the long form of the leptin receptor (LepRb) have lower cortical volume and decreased memory and exhibit depressive-like behaviors. A number of the signaling pathways regulated by LepRb are known, but how membrane LepRb levels are regulated in the central nervous system is not well understood. Here, we show that the lysosomal inhibitor chloroquine increases LepRb expression in hippocampal cultures, suggesting that LepRb is degraded in the lysosome. Furthermore, we show that leptin increases surface expression of its own receptor by decreasing the level of ubiquitinated LepRbs. This decrease is mediated by the deubiquitinase ubiquitin-specific protease 8 (USP8), which we show is in complex with LepRb. Acute leptin stimulation increases USP8 activity. Moreover, leptin stimulates USP8 gene expression through cAMP response element–binding protein (CREB)–dependent transcription, an effect blocked by expression of a dominant-negative CREB or with short hairpin RNA knockdown of CREB. Increased expression of USP8 causes increased surface localization of LepRb, which in turn enhances leptin-mediated activation of the MAPK kinase/extracellular signal–regulated kinase pathway and CREB activation. Lastly, increased USP8 expression increases glutamatergic synapse formation in hippocampal cultures, an effect dependent on expression of LepRbs. Leptin-stimulated synapse formation also requires USP8. In conclusion, we show that USP8 deubiquitinates LepRb, thus inhibiting lysosomal degradation and enhancing surface localization of LepRb, which are essential for leptin-stimulated synaptogenesis in the hippocampus.