bluuebunny/crossref_metadata_2025 huggingface dataset:
Unveiling the mechanism of Buddleja officinalis against esophageal squamous cell carcinoma through network pharmacology and molecular docking approaches
Authors: Chang Cheng , Zhen Yang Zhen , Sen Song Yin , Gao Na , Zhe Zhang Hao , Lin Zhang Xiao , Li Fan Tian
Published: March 2024

In this research, we aim to explore the underlying mechanism of Buddleja officinalis (BO) in inhibiting esophageal squamous cell carcinoma (ESCC) by means of network pharmacology and molecular docking approaches. First, BO component targets were determined from the Traditional Chinese Medicine Systematic Pharmacology and HERB databases (known as BenCaoZuJian in Chinese transliteration), and ESCC disease targets were identified from GeneCards and DisGeNET databases. Second, the Venny 2.1 online tool was utilized to visualize the intersection targets, and shared potential targets between BO and ESCC were identified using the STRING database. Third, the component-target-pathway networks were constructed using Cytoscape software. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes were utilized for further analyzing the mechanism of BO in inhibiting ESCC. Finally, molecular docking technique was employed to delineate the docking profiles of BO and determine the optimal active component, which is threonine protein kinase (AKT1). We screened six active components and 227 targets from BO, of which 24 were shared targets of ESCC and BO. The network pharmacology analysis indicated core targets with high degrees, namely, serum albumin, insulin-like growth factor 1 receptor, AKT1, estrogen receptor, and basic fibroblast growth factor receptor 1, which are the most likely binding sites for the active components in BO. The related signaling pathways underpinning the inhibition of ESCC by BO encompass MAPK signaling pathway, adhesion junction pathway, and gastric cancer pathway. Moreover, linarin was recognized as the most suitable component for AKT1. Our results revealed that BO exhibits multicomponent, multi-target, and multi-pathway characteristics, which offer a scientific foundation for elucidating its therapeutic mechanism in ESCC and present novel insights for future investigations.
Prognostic criteria for the outcome of the first psychotic episode
Authors: Kosovskyi Volodymyr
Published: March 2024

Based on the examination of 177 patients with a first psychotic episode (F20 — 53 individuals; F23 — 96 people and F25 — 28 people) and dividing them according to the criterion of response to therapy into two comparison groups (a group with symptomatic remission and a group with “residual” symptoms), a frequency analysis of their clinical and psychopathological, pathopsychological and neuropsychological characteristics and diagnostic markers of positive and negative prognosis of the outcome of the first psychotic episode were determined. It has been established that a positive prognosis of the outcome is determined, first of all, by clinical and anamnestic and pathopsychological features, while a negative prognosis is indicated by clinical and anamnestic and clinical and psychopathological features.
Key words: primary psychotic episode, prognosis, outcome, diagnostic markers
Inovação Sustentável em Empresas Ferroviárias
Authors: Sugahara Cibele Roberta , Fantini Bruna Nunes , Ferreira Denise Helena Lombardo , De Benedicto Samuel Carvalho
Published: March 2024

A competitividade das empresas pode ser favorecida por meio de práticas voltadas à inovação, sobretudo quando associadas à sustentabilidade. No setor ferroviário, a inovação ocorre a partir de melhorias operacionais, redução de custos e ampliação dos serviços prestados. Nesse sentido, o objetivo deste estudo é apontar a importância da inovação no contexto das empresas ferroviárias. O método utilizado é de abordagem qualitativa, com delineamento descritivo e explicativo. Para a coleta de dados foram realizadas entrevistas com três profissionais que atuam em uma empresa do setor ferroviário do estado de São Paulo. Na empresa estudada há um direcionamento de ações pautadas para a sustentabilidade com vistas a melhorar o desempenho das atividades operacionais. Ressalta-se a importância de investimentos em projetos que privilegiem o uso de materiais alternativos e respeitem a capacidade de suporte do planeta, como por exemplo a adoção de um combustível renovável. O estudo realizado demonstrou o potencial da geração de inovação aplicada à malha ferroviária brasileira, no entanto, é necessário orientar a inovação no processo das operações da empresa para mitigar os impactos ambientais.
Editorial volume 6, número 2
Authors: Sperancini José Henrique B. S. Sperancini , Vilha Anapatrícia Morales , Suen Alberto Sanyuan
Published: March 2024

Editorial
Roadmap aplicado à servitização
Authors: Costa Luccas , Narcizo Ramon Baptista , Cardoso Rodolfo , Tammela Iara
Published: March 2024

Desde 1980 o setor de serviços está despontando na liderança do mercado econômico. Essa tendência vem impactando a forma como as organizações são gerenciadas, uma vez que estas passaram a buscar integrar seus produtos e serviços (servitização) em busca de um pacote de valor para o cliente. Entretanto, o processo de integração de produtos e serviços pode-se demonstrar desafiador gerando custos e afetando a rentabilidade das organizações. Portanto um meio de auxiliar este processo está na utilização do roadmapping. Esta abordagem auxilia no gerenciamento e planejamento, sendo capaz de identificar e mapear estratégias para minimizar os impactos desta integração. Neste contexto, foi realizada uma revisão sistemática da literatura (RSL) para identificar documentos que correlacionem a aplicação do roadmapping suportando à servitização. Para complementar a pesquisa foi utilizada a ferramenta de software, VOSviewer, para análise e apresentação dos dados. Ao final, foi apresentado uma síntese dos resultados com os documentos selecionados.
Contribuições Teóricas e Reflexões Sobre a Abordagem Entrepreneuring para o Empreendedorismo
Authors: Julkovski Dulcimar José , Padilha Luccas Santin , Machado Hilca Pelizza Vier , Spuldaro Juliano Danilo
Published: March 2024

A abordagem entrepreneuring mostra-se em crescimento nos estudos em empreendedorismo. Este trabalho buscou compreender a evolução das discussões sobre a abordagem entrepreneuring no campo de estudo do empreendedorismo, retratando as subcategorias com as constituições. O trabalho evidencia por meio de uma revisão sistemática da literatura a evolução das percepções e seus reflexos no campo de estudo. A metodologia utilizada foi a revisão sistemática de literatura. Este trabalho contribui para a reflexão sobre a abordagem entrepreneuring e suas contribuições para o campo de estudo teórico e prático do empreendedorismo. O entrepreneuring, apresenta-se como um fenômeno complexo, não-linear e com aspectos econômicos, sociais, institucionais e culturais por meio das ações de um indivíduo ou grupo de indivíduos. A limitação deste trabalho e a string de busca que se combinada com outras bases, pode gerar novos resultados. Sugere-se que os resultados forneçam uma base para futuros estudos empíricos, como uma maneira de expandir o conhecimento das subcategorias e da forma como estão sendo praticadas nos contextos organizacionais.
Mudanças Climáticas e Veículos Elétricos
Authors: Sugahara Cibele , Campos Giovanni Moreira Rocha , Ferreira Denise Helena Lombardo , Silva Luiz Henrique Vieira da
Published: March 2024

O Antropoceno é uma época iniciada na segunda metade do século XX, marcada por eventos como o aquecimento global, a poluição, a destruição de campos e florestas, a acidificação dos oceanos e a perda da biodiversidade, que têm acarretado severos problemas socioeconômicos aos seres humanos e entraves para a vida no planeta. As medidas para mitigar os efeitos do aquecimento global são necessárias para a garantia das condições de vida e proteção contra os danos gerados na biosfera. As respostas encontradas para essas questões indicam a premente necessidade de ações orientadas para o atendimento dos Objetivos de Desenvolvimento Sustentável. Este artigo tem por objetivo apontar a importância dos veículos elétricos para uma economia de baixo carbono. Para tanto, fez-se uso de uma pesquisa qualitativa, exploratória e de caráter bibliográfico. No Brasil, devido à grande pressão exercida sobre os ecossistemas naturais, percebe-se a necessidade de políticas de incentivo à produção e comercialização de veículos elétricos, pautadas na redução das emissões de gases de efeito estufa dos veículos tradicionais como uma das formas de atender às metas do Acordo de Paris e dos Objetivos do Desenvolvimento Sustentável.
Inovações de Recursos Restritos como Resposta à Pandemia de COVID-19
Authors: Barbosa Gregorio Joana Maria , Mendes Borini Felipe
Published: March 2024

O presente estudo documenta e analisa casos de inovação de recursos restritos como resposta à pandemia de COVID-19, a fim de aprofundar o entendimento da trajetória de desenvolvimento dos projetos de inovação no dito contexto. Através de uma abordagem qualitativa de caráter exploratório alinhada à estudos de caso coletados, o estudo traz entrevistas em detalhes de inovações construídas durante a pandemia, sendo a dificuldade de difusão dos produtos para o mercado a principal problemática constatada. Como resultado, foi explicitado o processo prático de criação e desenvolvimento de uma inovação frugal, trazendo insumos capazes de orientar as partes interessadas com base em casos que mostram exemplos reais e recentes de tal modelo. Além disso, torna-se clara a crucialidade da participação ativa das universidades públicas brasileiras no processo de apoio à pesquisa e desenvolvimento.
Compreendendo os Fatores Motivacionais dos Colaboradores de uma Empresa de Construção Civil na Cidade de Santa Maria/RS
Authors: Castro Natiele Severino de , Santos Letícia Gomes dos , Souza Veridiane Bárbara de , Rosa Ana Claudia da
Published: March 2024

O presente trabalho traz como tema principal os fatores motivacionais de colaboradores em uma empresa situada na cidade de Santa Maria/RS, do setor da construção civil. Observando tais fatos, o objetivo deste estudo é investigar os fatores que levam a motivar os funcionários desta empresa em questão. O procedimento metodológico foi uma pesquisa aplicada, expondo os objetivos e abordando o problema de forma quantitativa. A coleta de dados ocorreu por meio de questionários estruturados com perguntas fechadas e foram respondidos por colaboradores disponíveis na cidade no dia da aplicação. Os resultados da presente pesquisa são apresentados em forma de tabelas que apontam a percepção dos colaboradores quanto aos fatores que os leva para motivação. A partir dos dados levantados, pode ser observado que os colaboradores se sentem motivados na organização, pois em uma escala likert de 05 pontos, a média geral foi de no mínimo média 4, o que se pode considerar um ótimo resultado, tanto pelo lado do empregado quanto pelo do empregador.
Trend Analysis of the Social Media in India: A Statistical Study
Authors: - Sintu Nitharwal , - Deepa Mordia
Published: March 2024

As a medium for social networking and content exchange, social media has become more significant and widely accepted in recent years. The specifics of social media usage have been taken into account. The general public is using the Internet much more frequently these days. Using social media sites like Facebook, WhatsApp, Linked In, Instagram, and many other social media platforms negatively impacts their productivity in the long run and has a substantial influence on both social and personal connections. In this article an estimate of the trend of social media platforms till 2030.
Establishing the Results of Homoeopathic Prescription through a Case Report of Vitiligo
Authors: - Sakshi Mewara , - S. N. Sharma , - Hari Shankar Tiwari , - Vikrant Rana
Published: March 2024

A common hypo- pigmentation disorder with acquired autoimmune origins, vitiligo can have major psychological effects. According to the distribution of skin depigmentation, vitiligo has been classified into segmental and non-segmental kinds. Case Summary: A 16-year-old male patient complained of a white patch on his scalp, eye, back, and throat that had been there for 2-2.5 years. The diagnosis of miasm and the totality of symptoms led to the prescription of the homoeopathic drug Syphilinum.
Efficiency Unleashed: Harnessing AI for Agile Project Management
Authors: - Anish Tadimarri , - Musarath Jahan Karamthulla , - Sanjeev Prakash , - Manish Tomar
Published: March 2024

This research paper explores the application of predictive analytics for real-time monitoring and feedback in project management. Through case studies of leading organizations such as Amazon, Uber, and NASA, the paper examines how predictive analytics enables organizations to optimize operations, improve efficiency, and achieve business objectives. The paper discusses the implementation of predictive analytics in various industries, including e-commerce, transportation, and space exploration, highlighting the benefits of real-time monitoring and feedback for enhancing decision-making, reducing costs, and improving customer satisfaction. By leveraging predictive analytics, organizations can anticipate trends, identify issues early, and make data-driven decisions to drive continuous improvement and innovation in project management practices.
Human Rights and Code of Ethics: Perspectives of Nurses and Patients
Authors: - Subin Jimmy
Published: March 2024

Human rights and ethics are essential to healthcare, particularly for those working in the nursing profession. The rights and well-being of patients are greatly affected by the activities of nurses, who are at the forefront of patient care. This article examines the relationship between the nursing code of ethics and human rights from the viewpoints of patients and nurses. Through an examination of the legal and ethical frameworks that direct nursing practice, together with the experiences and expectations of patients, this article aims to clarify the complex dynamics that exist between healthcare team members and their patients.
Antecedents of Export Performance of Food and Beverages MSMEs in India
Authors: - Anusuya Biswas
Published: March 2024

The Food and Beverages (F&B) sector has evolved as a sunrise sector of India. It is gearing-up its business at a rapid rate after the pandemic shocks. India is one of the largest foods producing nation in the world but due to its perishable nature the surplus food articles are converted to processed food and beverages products and exported to other countries. Even though the sector has good prospects to grow and attract foreign investment but most of the enterprises are micro, small, and medium. However, MSMEs are performing better in food and beverages exports. The present study has empirically investigated the export antecedents of India’s F&B MSMEs by using Random Effects Tobit Model in a firm level dataset. The study also analyzed the region-wise F&B export performance. The findings reveal that F&B industry is highly labour-intensive which requires more capital investment in physical assets like plant and machinery, cold storage facilities, warehousing, packing and packaging centers and so on. To stimulate the export performance, the F&B firms require to enhance the labour productivity by investing on the employees’ welfare and training activities as well as create awareness among them about the rules and regulations of WTO and FAO like food standard and safety regulations and packing and packaging standards etc. The region-wise analysis indicates that in F&B exports the Northern and Eastern regions have performed better whereas the North-Eastern region is more oriented towards the domestic market rather than the export market.
राज्य-राष्ट्र पर दीन दयाल उपाध्याय के विचार
Authors: - Praveen Chaudhry
Published: March 2024

इस लेख में, हम एक मजबूत भारत के गठन की स्पष्ट समझ हासिल करने के लिए पंडित दीनदयाल जी द्वारा प्रतिपादित राष्ट्र और राष्ट्रवाद की अवधारणा पर गहराई से विचार करेंगे। हम एक मजबूत भारत के निर्माण में उनकी महत्वपूर्ण भूमिका का पता लगाते हैं और भारतीय राष्ट्र, संस्कृति और राष्ट्रवाद के महत्व पर प्रकाश डालते हैं। इसके अलावा, हम भारतीय राष्ट्रवाद की तुलना पश्चिमी देशों से करते हैं, एक व्यापक विश्लेषण प्रदान करते हैं जो हम सभी को अपने राष्ट्र, संस्कृति और राष्ट्रवाद के महत्व की सराहना करने और समझने की अनुमति देता है। हमारे देश के प्रसिद्ध विचारक, दार्शनिक और राजनीतिक सामाजिक कार्यकर्ता पंडित दीनदयाल उपाध्याय जी के व्यक्तित्व ने न केवल युवाओं के लिए प्रेरणा का काम किया बल्कि उन्हें एक नई दिशा भी प्रदान की। दीनदयाल जी राष्ट्रवाद को संस्कृति के चश्मे से समझने के महत्व में दृढ़ विश्वास रखते थे। उन्होंने केवल इसके राजनीतिक या आर्थिक पहलुओं पर ध्यान केंद्रित करने के बजाय सांस्कृतिक दृष्टिकोण से भारत की आत्मा को समझने की वकालत की। उनके अनुसार किसी भी राष्ट्र की असली पहचान उसकी सांस्कृतिक जड़ों में जाकर ही जानी जा सकती है और इस संबंध में भारत सबसे आगे है।
Exploring the Impact of Buddhist Tourism and Pilgrimage on Cultural Exchange and Understanding: An Empirical Analysis
Authors: - Shushant Kumar Kushwaha
Published: March 2024

Buddhist tourism and pilgrimage are integral aspects of cultural and spiritual exploration, serving as bridges that connect individuals, communities, and nations. This empirical study employs a mixed-method approach, integrating surveys, interviews, and observational data, to investigate the profound impact of these journeys on promoting Buddhist understanding and facilitating cultural exchange.
Through the analysis of participant experiences across diverse destinations, our study unveils the transformative nature of Buddhist tourism and pilgrimage. Participants reported significant personal growth and spiritual enrichment, indicating that these journeys serve as catalysts for deepening individual spirituality. Furthermore, our findings highlight the pivotal role of these experiences in fostering cross-cultural dialogue and promoting mutual respect among diverse communities. Participants described meaningful interactions with individuals from unfamiliar cultural backgrounds, leading to a greater appreciation and understanding of cultural diversity.
Moreover, Buddhist tourism and pilgrimage emerge as platforms for fostering global harmony and enlightenment. By facilitating encounters between people of various beliefs and backgrounds, these journeys contribute to the promotion of peace and understanding on a broader scale. Participants reported a heightened sense of interconnectedness with humanity and a renewed commitment to promoting compassion and tolerance in their communities.
The implications of our findings extend beyond individual experiences to encompass broader societal benefits. Effective tourism management practices can leverage the transformative potential of Buddhist tourism and pilgrimage to promote sustainable development and cultural preservation in destination regions. Furthermore, our study underscores the importance of fostering interfaith dialogue and cooperation as essential components of global peace-building efforts.
Buddhist tourism and pilgrimage play vital roles in promoting cultural exchange, fostering understanding, and contributing to global harmony. By recognizing and harnessing the transformative power of these journeys, stakeholders can cultivate a more interconnected and compassionate world, grounded in mutual respect and appreciation for cultural diversity.
A Comparative Study Between the Contemporary Indian School Structure (Npe 1986) and the Structure Envisaged by NEP 2020
Authors: - Pujaita Nag
Published: March 2024

This paper mainly aims to depict an all round analysis and understanding on NEP2020, particularly on its School Structure. A brief qualitative analysis on the historical developments particularly NPE 1986, a comparative perspective between these two important policies of the Indian Education System. This brand new policy on Education has led to enormous interest of researchers in the field of Education and its policies.
Exploring the Impacts of India's National Education Policy on New Bharat Development
Authors: - Akanksha Singh
Published: March 2024

This article focuses on role of national education policy (NEP 2020) in Indian education system to provide strength. Education can only contribute to make our country developed nation by 2047. Authors have proposed a detailed outline in terms of framework that suggest step by step approach to achieve different path in parallel and simultaneous to speedup the growth of country in terms of different aspect of development which can make Bharat a developed nation. In the last , authors have also suggested different challenges which may occur to implement proposed framework.
Sentinel-2 Perspective: Land Use and Land Cover Dynamics in East and West Karbi Anglong
Authors: - Surjo Bey , - Abantika Pradhan
Published: March 2024

This study delves into the dynamics of land use and land cover (LULC) in East and West Karbi Anglong using Sentinel-2 satellite imagery. In response to escalating environmental changes, remote sensing technologies, particularly Sentinel-2, offer crucial insights for sustainable land management. Through an analysis of LULC patterns, the study aims to inform evidence-based decisions for environmental conservation and resource management in the region. The present study highlights the utility of remote sensing in LULC assessments and acknowledges the necessity for customized approaches in regions with distinctive features such as Karbi Anglong. Methodologically, temporally stratified Sentinel-2 datasets were utilized, with meticulous pre-processing and accuracy assessments ensuring reliability. Results indicate notable shifts in LULC classes, including urban expansion and vegetation decline. Despite limitations, such as potential inaccuracies in data processing, the study emphasizes the importance of monitoring environmental changes and advocating for sustainable land management strategies.
YUMMZ Sugar Free Ice Cream
Authors: - Shreya Jain , - S Nivetha , - Sanjaya V , - Md Shoaib Akhtar , - Padwalkar Anisha Sadanand
Published: March 2024

YUMMZ, epitomizes innovation and health-consciousness in the ice cream industry, striving to redefine indulgence with guilt-free frozen treats. At its core, YUMMZ is driven by a mission to revolutionize ice cream consumption, intertwining traditional Indian flavors with modern dietary considerations, thus
offering consumers a harmonious blend of taste and nutrition. Committed to this mission, YUMMZ sets forth ambitious goals, encompassing the development of diet ice cream options that are not only low in calories, sugar, and saturated fat but also imbued with the rich tapestry of Indian herbs and spices, aiming
to provide a novel experience that prioritizes health without compromising on indulgence. Moreover, customer satisfaction stands as a cornerstone of YUMMZ's ethos, with a focus on offering a diverse range of flavors, shapes, and toppings that cater to the varied preferences and dietary needs of consumers,
ensuring that each frozen delight is a personalized and delightful experience. This dedication to the customer extends beyond mere product offerings, as YUMMZ actively engages with its consumer base through both business-to-business and business-to-consumer channels, fostering connections and
gathering feedback to continuously refine its products and services, thereby cementing its position as a customer-centric brand. As YUMMZ looks towards the future, expansion looms large on its horizon, with plans to diversify its product offerings and distribution channels both nationally and internationally,
capitalizing on emerging trends in health-conscious eating and global flavor preferences, thus solidifying its status as a trailblazer in the ice cream landscape.
Entomofauna edáfica associada ao cultivo de algodão transgênico no cone sul de Rondônia
Authors: Machado Cardoso Lucas Henrique , Fonseca do Nascimento Aline , Martinho Silveira Herica , Oliveira Eduardo , Budach Silva Franco Leidiane
Published: March 2024

Â O estado de Rondônia estava incluído nas zonas de exclusão para o plantio do algodão geneticamente modificado. Essas áreas foram instituídas em 2005, pela Comissão Técnica Nacional de Biossegurança (CTNBio), com o objetivo de preservar a variabilidade de algodoeiros não cultivados (nativos e naturalizados) de eventuais efeitos adversos decorrentes do fluxo gênico com algodoeiros geneticamente modificados. No entanto, os insetos endêmicos da região, pragas e inimigos naturais, associados ao algodoeiro geneticamente modificado, não foram levantados. Tais informações são fundamentais para a atualização de programas de manejo integrado de pragas. Desse modo, o objetivo do presente estudo foi avaliar a entomofauna associada Ã  cultura do algodoeiro geneticamente modificado na região do Cone Sul de Rondônia, tendo como enfoque as áreas plantadas na cidade de Vilhena, auxiliando na elaboração do manejo integrado de pragas na região. Foi possível observar que a maioria dos insetos encontrados nas amostras constituem-se de inimigos naturais de pragas agrícolas ou mesmo recicladores de matéria orgânica. Tesourinhas (Labiduridae), moscas (Muscidae), abelhas (Apidae), besouros (Carabidae), moscas de carne (Sarcophagidae) e formigas (Formicidae) foram os insetos mais representativos encontrados. Observou-se que a maioria dos insetos encontrados são benéficos para o solo e para cultura, sendo importante buscar meios de controles de pragas que sejam seletivos, com o intuito de preservar essa entomofauna encontrada.
Analisis Formalin Dalam Ikan Tongkol Pindang Sebelum Perebusan dan Setelah Perebusan Dalam Berbagai Waktu
Authors: Kristianingsih Yuli , Sugiantari Nining , Rahayu Cahyawati , Nurdiani Catu Umirestu , Ardiansyah Renaldi , Masdianto Masdianto , Sediarso Sediarso
Published: March 2024

Ikan tongkol pindang merupakan olahan hasil laut yang memiliki kandungan protein tinggi sehingga ikan tongkol pindang mudah membusuk. Formalin digunakan sebagai pengawet untuk memperpanjang masa penyimpanan ikan tongkol pindang. Penggunaan formalin dapat menyebabkan bahaya bagi kesehatan manusia. Formalin dilarang digunakan sebagai pengawet pangan berdasarkan Peraturan Menteri Kesehatan Indonesia Nomor 33 tahun 2012.Tujuan penelitian ini untuk mengindentifikasi dan mengetahui kadar formalin serta melihat perbedaan penurunan kadar formalin sebelum dan sesudah perebusan pada ikan tongkol pindang dengan waktu 5, 10 dan 15 menit. Identifikasi formalin pada ikan tongkol pindang menggunakan pereaksi KMnO4. Penetapan kadar dilakukan dengan menggunakan metode spektrofotometri. Hasil uji kualitatif didapat 6 (100%) sampel ikan tongkol pindang positif mengandung formalin. Rata-rata penurunan kadar formalin setelah perebusan ikan tongkol pindang dengan lama waktu 5 menit 93,02 %, 10 menit 95,63 % dan 15 menit 97,44 %. Hasil uji One way Anova didapatkan p value 0,000 0,05 terjadi penurunan kadar formalin yang signifikan pada ikan tongkol pindang dengan perbedaan lama perebusan. Simpulan semakin lama perebusan maka penurunan kadar formalin ikan tongkol pindang semakin tinggi.Kata kunci : Ikan Tongkol Pindang, Formalin, Spektrofotometri,
Gambaran Hasil Pemeriksaan Anti–HIV dan HBsAg Metode Immunochromatography Tes Pada Ibu Hamil Di RSAB Harapan Kita Jakarta
Authors: Widhyasih Retno Martini , Nengsih Maharani Kurnia , Zuraida Zuraida
Published: March 2024

Isu kesehatan ibu dan anak tetap menjadi fokus perhatian berbagai pihak di tingkat global, regional dan Indonesia. Dalam upaya menurunkan kematian ibu serta melahirkan generasi yang sehat dan berkualitas yang merupakan tujuan pelayanan kesehatan ibu sebagaimana diamanatkan dalam UU Kesehatan, maka pelayanan antenatal yang berkualitas merupakan bagian yang sangat penting dan akan memberikan kontribusi yang sangat besar dalam mencapai tujuan tersebut, Salah satu penyakit yang harus dideteksi selama kehamilan adalah infeksi HIV dan Hepatitis B pada ibu hamil. Lebih dari 90% bayi terinfeksi HIV tertular dari ibu HIV selama kehamilan, saat persalinan dan menyusui. Tujuan penelitian adalah mengetahui gambaran hasil pemeriksaan Anti-HIV dan HBsAg pada ibu hamil di RSAB Harapan Kita. Metode penelitian ini adalah deskriptif menggunakan data sekunder berdasarkan Rekam Medis RSAB Harapan Kita periode Januari – Juni 2022 dengan responden sebanyak 495 pasien ibu hamil yang melakukan pemeriksaan Anti-HIV dan HBsAg. Simpulan hasil penelitian ini menunjukkan gambaran hasil pemeriksaan Anti-HIV pada ibu hamil dengan hasil Reaktif sebanyak 1 orang (0,2 %) dan HBsAg Reaktif sebanyak 8 orang (1,6 %). Ibu hamil hendaknya agar lebih meningkatkan kewaspadaan dan menghindari faktor-faktor risiko yang bisa menyebabkan penularan penyakit HIV dan Hepatitis B untuk mencegah terjadinya penularan secara kongenital kepada janinnya.Kata kunci : HIV, Hepatitis B, Ibu hamil
Gambaran Nilai Elektrolit Darah Pada Orang Dengan Gangguan Jiwa Di Rumah Sakit Khusus Daerah X
Authors: Nurdiani Catu Umirestu , Ramadhan Putri Aulia , Kristianingsih Yuli , Rahayu Cahyawati , Sugiantari Nining
Published: March 2024

Elektrolit darah adalah gabungan dari zat kimia yang terurai menjadi ion yang bermuatan positif atau negatif, seperti natrium, kalium, dan klorida. Ketidakseimbangan elektrolit dapat menyebabkan manifestasi gangguan jiwa. Hal ini terjadi karena keseimbangan elektrolit dikaitkan dengan gangguan afektif pada orang dengan gangguan jiwa. Contoh gangguan elektrolit darah yaitu hipernatremia, hipokalemia, dan hiperkloremia. Penelitian ini bertujuan untuk mengetahui gambaran nilai elektrolit darah pada orang dengan gangguan jiwa, mengetahui persentase abnormalitas berdasarkan jenis kelamin dan kelompok umur. Penelitian ini menggunakan metode deskriptif analisis data sekunder dengan menghitung rata-rata dan persentase nilai elektrolit darah abnormal yang disajikan dalam bentuk tabel disertai narasi. Data yang digunakan sebanyak 182 orang dengan gangguan jiwa. Pengambilan data dilakukan di laboratorium RSKD X bulan April 2023. Didapatkan hasil pemeriksaan elektrolit darah: rerata natrium 139,18 mmol/L, rerata kalium 3,57 mmol/L, dan rerata klorida 103,9 mmol/L. Hasil abnormal natrium yaitu 8 pasien perempuan (10%) dan 4 pasien berumur 59 tahun (lansia) (21%), kalium yaitu 47 pasien perempuan (57%) dan 63 pasien berumur 19-44 tahun (dewasa) (51%), dan klorida yaitu 37 pasien perempuan (45%) dan 16 pasien berumur 45-59 tahun (pra lansia) (48%). Penelitian ini dapat digunakan sebagai referensi tambahan bagi institusi mengenai judul yang sama dan disarankan memperluas cakupan penelitian. Didapatkan persentase nilai abnormalitas pemeriksaan natrium pada orang dengan gangguan jiwa di RSKD X yaitu 13 pasien (7%), pemeriksaan kalium yaitu 91 pasien (50%), dan pada pemeriksaan klorida yaitu 74 pasien (41%).Kata kunci : Elektrolit, Darah, Orang dengan Gangguan Jiwa
Implementasi Sistem Informasi Pendaftaran Rehabilitasi di Satuan Reserse Narkoba Polrestabes Palembang Berbasis Web
Authors: Hermawan Aldi , Andri Andri , Yadi Ilman Zuhri , Irawan Dedi
Published: March 2024

Dalam era teknologi, pengembangan sistem informasi menjadi penting. Di Satres Narkoba Polrestabes Palembang, proses pendaftaran rehabilitasi masih manual dan rentan kesalahan. Untuk mengatasi masalah ini, solusi berbasis web menjadi alternatif yang memungkinkan pendaftaran online yang efisien. Dalam konteks ini, metode Rapid Application Development (RAD) dapat mempercepat pengembangan sistem. Metode ini memfasilitasi interaksi pengguna yang aktif dan fleksibel, sehingga mempercepat implementasi sistem. Selain itu, penerapan metode First-In-First-Out (FIFO) dalam mengatur jadwal dokter juga vital. Metode FIFO memastikan prioritas pelayanan berdasarkan waktu pendaftaran, meningkatkan keadilan dan efisiensi. Penelitian ini bertujuan merancang dan mengimplementasikan Sistem Informasi Pendaftaran Rehabilitasi berbasis web di Sat Resnarkoba, mengadopsi metode RAD dan penerapan FIFO. Penelitian ini berhasil mengimplementasikan metode RAD dalam pengembangan Sistem Informasi Pendaftaran Rehabilitasi berbasis web di Sat Resnarkoba Polrestabes Palembang. Pendekatan ini memungkinkan iterasi yang cepat dan efektif dalam pengembangan, memfasilitasi komunikasi yang baik antara pemangku kepentingan, serta memungkinkan penyesuaian yang lebih baik terhadap kebutuhan yang berkembang. Hasil penelitian menunjukkan bahwa sistem informasi yang diimplementasikan memberikan manfaat yang signifikan dalam mengelola proses rehabilitasi. Antarmuka pengguna yang intuitif dan responsif pada halaman-halaman menu, serta adopsi metode FIFO dalam penjadwalan terapi menjadi nilai tambah. Halaman Tampilan Menu Jawaban Pasien juga memungkinkan dokter dan admin untuk berinteraksi secara efektif dengan pasien, meningkatkan komunikasi dan respons yang tepat terhadap kebutuhan pasien.
Analisis Kesuksesan Sistem Dapodik dengan Model Delone dan McLean pada SMA Kabupaten Ogan Komering Ilir
Authors: Natasya Talia , Farozi Mohamad
Published: March 2024

Pemanfaatan teknologi informasi dan komunikasi (TIK) dalam pengelolaan informasi di Sekolah Menengah Atas (SMA) memiliki peran vital dalam meningkatkan efisiensi dan akurasi. Kabupaten Ogan Komering Ilir (OKI) di Sumatera Selatan menghadapi berbagai tantangan dalam penerapan TIK. Keberhasilan sistem informasi data pokok pendidikan (Dapodik) di tingkat SMA di Kabupaten OKI dievaluasi menggunakan model DeLone dan McLean. Model DeLone and McLean menggunakan enam pengukuran kesuksesan Sistem Informasi yaitu kualitas sistem (System Quality), kualitas informasi (Information Quality), kualitas layanan (Service Quality), penggunaan (Use), kepuasan pemakai (User Satisfaction), dan manfaat bersih (Net Benefit). Penelitian ini bertujuan untuk menganalisis tingkat kesuksesan penerapan sistem informasi data pokok pendidikan (Dapodik) di SMA Kabupaten OKI. Hasil dari penelitian ini diharapkan akan memberikan wawasan yang berharga bagi penyempurnaan sistem informasi pendidikan dan pengembangan lebih lanjut di masa mendatang. Hasil penelitian menunjukkan bahwa kualitas sistem (System Quality) dan kualitas layanan (Service Quality) memiliki dampak yang signifikan terhadap penggunaan sistem (Use) dan kepuasan pengguna (User Satisfaction). Temuan ini menggarisbawahi pentingnya menyediakan sistem yang handal, responsif, dan mudah digunakan, serta layanan yang memuaskan agar pengguna merasa terdorong untuk aktif menggunakan sistem dan merasa puas dengan pengalaman penggunaan. Meskipun kualitas informasi (Information Quality) dan manfaat bersih (Net Benefit) tidak memiliki pengaruh langsung yang signifikan terhadap variabel lain dalam model, kedua aspek ini tidak boleh diabaikan. Kualitas informasi yang baik dan manfaat bersih yang diperoleh masih memiliki dampak penting dalam mendukung pengambilan keputusan dan efisiensi proses pendidikan.
Perancangan Tim Siap Tanggap Insiden Siber-CSIRT: Studi Kualitatif Berdasarkan Business Impact Analysis di Bank XYZ
Authors: Putra Hendra Yada , Herdiansyah M. Izman , Sutabri Tata
Published: March 2024

Dalam operasional perbankan salah satu risiko yang berpotensi meningkat seiring dengan pemanfaatan TI pada skala yang lebih besar adalah risiko yang ditimbulkan oleh ancaman dan insiden siber karena pemanfaatan TI sudah sebagian besar melalui media siber. Pada Bank XYZ semua insiden keamanan siber dikelola oleh Divisi Teknologi Informasi dan belum ada batasan secara spesifik menangani insiden siber khusus skala besar. Insiden siber khusus skala besar terkait dengan pembentukan Tim kerja dengan fungsi yang tidak hanya melakukan pemulihan insiden secara teknis saja, melainkan juga secara berkolaboratif dari sisi non teknis. Mengingat reputasi bank dipertaruhkan saat pemulihan insiden keamanan berlangsung. Selain itu perlu adanya pengaturan secara spesifik mengenai alur kerja, lingkup layanan dan limit dampak yang akan menjadi trigger kapan tim ini akan mulai bekerja. Diperlukan penelitan dengan tujuan untuk mengembangkan pengelolaan insiden keamanan siber yang lebih efektif dan efisien dalam bentuk perencanaan Tim Siap Tanggap Insiden Siber (TTIS), atau lebih dikenal dengan Computer Security Incident response Team (CSIRT) yang mengacu pada tingkat kritikalitas pada analisis Business Impact Analysis (BIA). Penelitian mengacu pada standard ISO/TS 22317:2021 sebagai panduan analisis BIA dan ISO/IEC 27035:2023 dalam penyusunan kerja Tim TTIS. Hasil BIA memberikan gambaran yang jelas mengenai tingkat kritikalitas proses bisnis yang dimiliki Bank. Penentuan tingkat kritikalitas sangat membantu dalam penyusunan tim TTIS/CSIRT yang efektif dan efisien dalam upaya penangan insiden keamanan informasi skala besar.
Research of the Process of Electrochemical Deposition of Chromium in the Presence of a Composite Compound Based on Detonation Diamond-Containing Carbon
Authors: Dolmatov Valerii
Published: March 2024

The purpose of the study is to develop a method for obtaining high-quality electrochemical chromium coating using a new type of diamond-containing additive that has significant advantages over traditionally used detonation nanodiamonds (DNA) in the form of aqueous suspensions. Detonation diamond-containing carbon (DDC) obtained by detonation of charges from tetryl was used as an additive. DDC contains 63,0 wt. % DNA and 4.4 wt. % non-combustible impurities. We used standard chromium electrolyte: CrO3 - 250 g/l, H2SO4 – 2,5 g/l, DNA – from 0,2 to 5 g/l, traditional methodologies and algorithm of experimentation. The scope of the study is limited to the creation and application of a specific, easy to handle and prepare formulation with DDC. DDC can be added to the standard chromium electrolyte directly or in the form of freshly prepared aqueous suspension, it is environmentally safe.
The originality of the work lies in the application of a cheap diamond-containing product obtained directly after the explosion of an individual explosive (tetryl) and providing stability of DDC suspensions. An increase in microhardness of wear-resistant chrome coating by 1,5 times (up to 11 GPa) and hard chrome coating by 1,7 times (up to 13,3 GPa) was achieved. The wear resistance of the obtained coatings increased by 1,9 times. Concentration (per pure detonation nanodiamond (DNA)) from 0,63 to 3,15 g/l in the electrolyte (very low).
Beyond Grid Girls and Checkered Flags: Exploring Sexual Objectification at Motorsport Events
Authors: Smyth Louise , Morgan Nigel , Vernes Whitney
Published: March 2024

Motorsport has long been a very male-oriented sport, its events synonymous with conventionally attractive, provocatively dressed “grid girls.” This research note examines the issue of sexual objectification in the male-dominated motorsport industry, shedding light on its
prevalence and impact through findings from an online survey. While previous studies have focused on objectification in service industries, such as airlines, sports and events environments remain underexplored. The study highlights the mental health implications of employees’ objectification,
emphasizing the harmful effects of stereotyping individuals, reducing them to objects of desire, and perpetuating gender inequality. Our exploratory study advocates for promoting inclusivity, respect, and empowerment within the industry to combat sexism and objectification, calling for increased
awareness and understanding in the broader events sector and specifically in motorsports.
Lifelong Educational and Decolonization Programs for the Batwa Indigenous People of Southwestern Uganda
Authors: Sekiwu Denis , Adyanga Francis Akena , Genza Gyaviira Musoke , Rugambwa Nina Olivia , Muwagga Anthony Mugagga
Published: March 2024

This article is based on a study conducted among the Batwa Indigenous people in southwestern Uganda between 2021 and 2022. The study aimed to explore culturally relevant lifelong education and decolonization programs for the Batwa people. Using indigenous research methodology, 60 participants comprising of elders, parents, children and teachers were recruited from the Batwa community for the study. We used Egalitarian liberalism and justice in education (ELJE) theory as analytical framework. Key findings demonstrate that participants were conscious of the challenges faced by their community and collectively brainstormed practical redress measures. These measures include but are not limited to setting up an entrepreneurship education program, vocational and skilling programs, and promotion of Rutwa language. Besides, some specific Batwa life skills identified by participants are briefly described as imperative for integration in the schooling system to achieve the decolonization mission
PENGARUH LEARNING AGILITY TERHADAP KINERJA KARYAWAN PADA OTORITAS JASA KEUANGAN REGIONAL 6 SULAWESI MALUKU DAN PAPUA
Authors: Salsabila Adinda Tasya , Megawaty Megawaty
Published: March 2024

This study aims to analyze and determine the effect of people agility, results agility, mental agility, and change agility on employee performance at the Regional Financial Services Authority offices 6th Sulawesi, Maluku and Papua. The research method used in this study is multiple linear regression with a sample of 40 respondents who are organic employees at the OJK Regional 6th Sulampua office. Data was collected by distributing questionnaires containing statements about learning agility. The results of the study partially show that people agility, results agility, mental agility, and change agility each have a positive and significant effect on employee performance. The results of the study simultaneously show that people agility, agility results, mental agility, and change agility have a positive and significant effect on employee performance.
ANALISIS MOTIVASI DALAM PENINGKATAN KINERJA KARYAWAN PADA PERUMDA BANK GRESIK
Authors: Rahmawati Ramadiva , Cahyadi Nur
Published: March 2024

Salah satu fenomena yang tampak pada Perumda Bank Gresik adalah permasalahan mengenai kinerja karyawan. Berdasarkan data kinerja dalam bentuk KPI dari beberapa karyawan, teridentifikasi karyawan belum mampu memaksimalkan kinerjanya pada aspek tertentu, padahal Perumda Bank Gresik tengah menghadapi persaingan bisnis yang ketat. Hal ini terjadi diduga karena terdapat karyawan yang mengalami stress, tekanan berlebihan, serta faktor lain yang termasuk ke dalam aspek penghambat motivasi kerja. Penelitian ini bertujuan untuk menganalisis hubungan motivasi kerja terhadap kinerja karyawan yang ditinjau dengan beberapa faktor dari masing-masing variabel. Metode yang digunakan dalam penelitian ini adalah jenis penelitian deskriptif statistik. Pengumpulan data dilakukan dengan cara observasi dan interview secara terbatas. Adapun penelitian dilakukan di Perumda Bank Gresik selama periode Agustus – Oktober 2023. Berdasarkan hasil analisis, didapat motivasi kerja yang dimiliki oleh para karyawan diorientasikan pada kebutuhan secara terbatas terutama gaji atau penghasilan sehingga para karyawan tidak memprioritaskan penilaian kerja sehingga berdampak pada kinerja karyawan.
Pengaruh Jumlah Kasus Covid-19 terhadap Harga Saham dan Profitabilitas pada Perusahaan Indeks LQ45
Authors: Sucayono Sucayono
Published: March 2024

The Covid-19 outbreak in Indonesia has had many negative impacts on the national economy. Many sectors have been affected by the emergence of this virus, including the Indonesian capital market. This research aims to find out the impact of the number of Covid-19 cases on share prices and profitability of companies listed in the LQ 45 Index in the 2020-2022 period. This research applies a quantitative approach using secondary data obtained from the official website of the Indonesian Stock Exchange and the internet. Regression analysis was carried out on the 33 companies. The result of this research shows that the number of Covid-19 cases does not have a significant influence on share prices and profitability of companies of the LQ 45 Index.
Attentional biases to signals of negative information: Reliable measurement across three anxiety domains
Authors: Basanovic Julian
Published: March 2024

Cognitive models propose that individuals with elevated vulnerability to experiencing negative emotion are characterised by biased attentional responding to negative information. Typically, methods of examining these biases have measured attention to pictures of emotional scenes, emotional faces, or rewarding or feared objects. Though these approaches have repeatedly yielded evidence of anxiety-linked biases, their measurement reliability is suggested to be poor. Recent research has shown that attentional responding to cues signalling negative information can be measured with greater reliability. However, whether such biases are associated with emotion vulnerability remains to be demonstrated. The present study conducted three experiments that recruited participants who varied in trait and state anxiety (N = 134), social anxiety (N = 122), or spider fear (N = 131) to complete an assessment of selective attention to cues signalling emotionally congruent negative information. Analyses demonstrated that anxiety and fear were associated with biased attentional responding to cues signalling negative information, and that such biases could be measured with acceptable reliability (rsplit-half = .69–.81). Implications for research on the relation between emotion and attention are discussed.
Penerapan Multimedia Pembelajaran Berbasis Masalah dalam Meningkatkan Hasil Belajar dan Keterampilan Berpikir Tingkat Tinggi
Authors: Meike Paat  , Armstrong F. Sompotan  , Aneke Pesik  , Yohanes Bery Mokalu  , Imriani Moroki
Published: March 2024

Tujuan penelitian yaitu mengoptimalkan hasil belajar serta keterampilan berpikir tingkat tinggi siswa dalam pembelajaran dengan penerapan multimedia pembelajaran menggunakan model pembelajaran berbasis masalah pada Siswa SMP Negeri 7 Bitung. Penelitian tindakan kelas diimplementasikan lewat dua siklus, pada tiap siklus terdapat tiga sesi. Subjek penelitian ini yaitu 20 siswa kelas 9, dengan tahapan penelitian terdiri dari perencanaan, pelaksanaan, observasi, serta refleksi. Pengumpulan data melalui tes dengan menggunakan soal high order thinking skills, observasi, serta dokumentasi, dan dianalisis menggunakan rumus, rata-rata, dan persentase. Analisis yang dilakukan terdapat peningkatan hasil belajar, serta ketrampilan berpikit tingkat tinggi. Peningkatan itu terlihat dari nilai ketuntasan siswa dan ketuntasan klasikal yang meningkat pada setiap siklus, dari rata-rata nilai siklus I sejumlah 52, pada siklus II sejumlah 69, dan pada siklus III menjadi 82. Jumlah Siswa yang memenuhi nilai kriteria ketercapaian tujuan pembelajaran yaitu 8 Siswa (siklus I), 13 Siswa (siklus II), menjadi 18 (Siklus III). Pertambahan persentase ketuntasan klasikal siswa dari siklus I sejumlah 40%, siklus II 65%, menjadi 90% pada siklus III, kesimpulan dari penelitian ini yaitu terjadi peningkatan hasil belajar serta keterampilan berpikir tingkat tinggi Siswa.