bluuebunny/crossref_metadata_2025 huggingface dataset:
Gemcitabine-Resistance Reversion of Cucurmosin in Human Pancreatic Cancer Cells
Authors: Wang Congfei , Fu Mingjuan , Huang Heguang , Xie Jieming
Published: July 2021

Objective To investigate the effects of cucurmosin (CUS) on proliferation and drugs resistance in gemcitabine (GEM) human pancreatic cancer cell PANC-1RG7. Methods The ultrastructural changes of PANC-1RG7 cells after CUS intervention were observed by transmission electron microscope. Flow Cytometer (FCM) was used to detect the effect of CUS on the growth cycle of PANC-1RG7 cells. We used colony formation experiment, Sulforhodamine B assays and subcutaneous implantation tumor model to observe the proliferation inhibition and reversal drug-resistance reversion of CUS on PANC-1RG7 in vitro and in vivo. Western blot was used to observe the expressions of RRM1, RRM2, PI3K, Akt, mTOR and other proteins related to apoptosis after CUS intervention. Results After CUS intervention, PANC-1RG7 cells were obviously apoptotic with large number of vacuoles and apoptotic bodies. Compared with parental cell PANC-1, GEM-resistant cell PANC-1 was more sensitive to CUS. The combination of GEM and CUS at different concentrations showed synergistic effect. At the concentration of CUS with the inhibition rate of 10%, the reversal multiples and the reversal efficiency were 1.78±0.65 and 50.13±16.87%, respectively. Subcutaneous implantation tumor model confirmed the proliferation inhibitory effect of CUS in vitro. Western blot confirmed that CUS down-regulated the expressions of RRM1, RRM2, PI3K, Akt and mTOR. Conclusion CUS can significantly inhibit PANC-1RG7 cell proliferation in vivo and in vitro, and can reverse cell GEM-resistance.
Factors associated with hospitalization outcomes for cases of anemia in pregnancy at a regional level in Burkina Faso
Authors: ILBOUDO Bernard , Savadogo Léon Gueswendé Blaise , Traoré Isidore , Meda Clément Zemlé , Hien Alain , Kinda Maurice , Hien Hervé , Dramaix-Wilmet Michèle , Donnen Philippe
Published: July 2021

Background
The complications related to anemia in pregnancy are common in referral hospitals of Burkina Faso. This study aimed to analyze the hospital discharge results of cases of anemia for the mother-pregnancy entity at a regional level in Burkina Faso.
Methods
An hospital-based historical cohort study was conducted on anemia cases identified from hospital records of pregnant women admitted between 2009 and 2011 in the maternity wards of public referral hospitals of the “Cascades” region in Burkina Faso. The hospitalization result was favorable if it was satisfactory for both the mother and the pregnancy, and unfavorable in the other cases. The factors associated with unfavorable hospital discharge were identified through multivariable logistic regression.
Results
A total of 1815 cases of biological anemia in pregnancy were included in the study. The result of hospitalization for the mother-pregnancy entity was unfavorable in 42.6% of cases. The factors associated with unfavorable hospital discharge were rural residence (OR = 1.32; 95% CI: 1.00-1.74), evacuation cases (OR = 1.96; 95% CI: 1.48–2.60), 1st or 2nd trimester of pregnancy (OR = 2.74; 95% CI: 2.03–3.68), severe anemia (OR = 2.46; 95% CI: 1.75–3.46), moderate anemia (OR = 1.39; 95% CI: 1.05–1.85) and poor quality of anemia prevention (OR = 2.81; 95% CI: 1.62–4.88). The unfavorable hospital discharge was less frequent in women in couple (OR = 0.46; 95% CI: 0.26–0.84), in nulliparous and primiparous (OR = 0.69; 95% CI: 0.54–0.88). Age, income level and reason for admission were not associated with the unfavorable hospital discharge.
Conclusion
There was a high frequency of unfavorable hospital discharge of anemia cases for the mother-pregnancy entity in Burkina Faso. Multiple maternal factors were associated with these issues.
WITHDRAWN: Carbon Monoxide Releasing Molecule-2 Protects Intestinal Mucosal Barrier Function of Rat Undergoing Cardiopulmonary Resuscitation via Attenuation of TNF-α/NF-κB Signaling
Authors: Niu Qingsheng , Liu Fang , Zhang Jun , Yang Xiaojun , Wang Xiaohong
Published: July 2021

The unique features of post–cardiac arrest pathophysiology are often superimposed on the disease or injury, causing the cardiac arrest, as well as underlying comorbidities. Exogenous carbon monoxide (CO) was reported to reduce ischemia-reperfusion injury (IRI). This study aimed to assess the effects of CO releasing molecule-2 (CORM-2) on intestinal mucosal barrier function after cardiopulmonary resuscitation (CPR) in rats. For this purpose, we established a rat model of asphyxiation-induced cardiac arrest and resuscitation to study intestinal IRI, and measured the serum level of intestinal fatty-acid binding protein (I-FABP). The expression levels of claudin-3, occludin, ZO-1, tumor necrosis factor-alpha (TNF-α), interleukin-10 (IL-10), and nuclear factor kappa B (NF-κB) p65 were detected by Western blotting. CORM-2 up-regulated the expression levels of tight junction proteins (claudin-3, occludin, and ZO-1) in intestinal mucosa, leading to the reduction of the permeability of intestinal mucosa and reduced the release of proinflammatory cytokines. Besides, the CORM-2 exhibited anti-inflammatory effects by regulating the TNF-α/NF-κB pathway. In conclusion, CORM-2 treatment is clinically significant, preventing intestinal mucosal damage as a result of IRI during CPR.
Emulation of Ternary and Quaternary Logic Quantum Computers By 2-Dimensional Analog Signal Processing
Authors: Mathivanan Anbuselvi , Prabhu Prithviraj , Venkataraman Rishab , Palani Saravanan
Published: July 2021

In this paper, a novel method for the emulation of qutrit and ququart based quantum computers is proposed. The Hilbert space and Bloch sphere representations of qutrits are initially discussed, preceding the emulation of a single qutrit using a classical system. The signal representing the state of the quantum system is defined as the sum of quadrature and in-phase 2-dimensional space-varying signals, which represent the basis states of the quantum system. Focus is mainly conferred on the frequency-domain representation of the signal, due to an innate bijective mapping found between the dimensions in the Hilbert space and the frequencies of the signal. An m -qutrit addressing scheme is then proposed which is used in the application of quantum ternary gates and measurement operations. The proposed theory is then used to simulate a ternary version of the Deutsch-Jozsa algorithm on MATLAB. This paper also includes a section on the extension of the theory to the case of ququarts. It concludes with a brief introduction to a potential system for emulation, and lists algorithms that can be implemented on the proposed system.
A Material Removal Model for Nonconstant-contact Flexible Grinding
Authors: Ye Huan , Chen Zhitong , Xie Zhuoqun , Li Shangbin , Su Shuai
Published: July 2021

Contact calculation is of great importance in predicting the material removal (MR) of flexible grinding process (FGP). The contact is mostly considered approximately constant in the existing MR models, while the situations that contact varies a lot after FGP are ignored. Therefore, a novel model is proposed in this paper to take those situations into consideration. Firstly, the nonconstant-contact situation is introduced. Then an equivalent method is developed to convert the nonconstant-contact grinding process into the accumulation of several quasi-constant-contact grinding processes. Based on the equivalent method, a MR model is established, and the procedure to obtain the model parameters by the finite element analysis (FEA) is introduced. In the end, the equivalent method and the MR model are tested by a series experiments of different process parameters. Results show that the proposed MR model can predict the material removal effectively for the nonconstant-contact situations.
Recursive Feature Elimination with Ridge Regression (L2) Machine Learning Hybrid Feature Selection Algorithm for Diabetic Prediction using Random Forest Classifer.
Authors: venkatachalam K , Prabhu P , Balaji B saravana , Abouhawwash Mohamed , Rajadevi R
Published: July 2021

In day today life, diabetes illness is increasing in count due to the body not able to metabolize the glucose level. The prediction of the right diabetes patients is an important research area that many researchers are proposing the techniques to predict this disease through data mining and machine learning methods. In prediction, feature selection is one of the key concept in preprocessing so that the features that are relevant to the disease will be used for prediction. This will improve the prediction accuracy. Selecting right features among the whole feature set is a complicated process and many researchers are concentrating on it to produce the predictive model with high accuracy. In this proposed work, the wrapper based feature selection method called Recursive Feature Elimination (RFE) is combined with Ridge regression (L2) to form a hybrid L2 regulated feature selection algorithm to overcome the overfilling problem of the data set. Over fitting is the major problem in feature selection which means that the new data are not fit to the model since the training data is small. Ridge regression is mainly used to overcome the overfitting problem. Once the features are selected using the proposed feature selection method, random forest classifier is used to classify the data based on the selected features. The proposed work is experimented in PIDD data set and the evaluated results are compared with the existing algorithms to prove the accuracy effect of the proposed algorithm. From the results obtained by proposed algorithm, the accuracy of predicting the diabetes disease is high compared to other existing algorithms.
Indirect response of the temperature, humidity, and rainfall on the spread of the COVID-19 over the Indian monsoon region
Authors: Mehta Sanjay Kumar , A Aravindhavel , Reddy T. V. Ramesh , Ali Saleem , Mehta Shyam Bihari , Philip Sachin , Purushotham Pooja , Betsy K. B.
Published: July 2021

This paper examines the role of the meteorological variable on the spread of the ongoing pandemic coronavirus disease 2019 (COVID-19) across India. COVID-19 has created an unprecedented situation for public health and brought the world to a standstill. The COVID-19 has caused more than 1,523,242 deaths out of 66,183,029 confirmed cases and around the world till the first week of December 2020. We have examined the surface temperature, relative humidity, and rainfall over five cities namely Delhi, Mumbai, Kolkata, Bengaluru, and Chennai severely affected by COVID-19. It is found that the prevailing southwest (SW) monsoon during the pandemic has acted as a natural sanitizer in limiting the spread of the virus. The day-to-day variation of the meteorological parameters and COVID-19 cases clearly demonstrate both surface temperature and relative humidity play a vital role in the indirect transport of the virus. Our analysis reveals that the majority of the COVID-19 cases fall within the surface temperature ranging from 24oC to 30oC and relative humidity ranging from 50–80%. At a given temperature, COVID-19 cases show a large dependency on the relative humidity which attributes those coastal environments were more prone to infections. Wavelet transforms coherence analysis of the daily COVID-19 cases with temperature and relative humidity reveal a significant coherence within 8 days.
Formación con perspectiva de género, una tarea pendiente
Authors:   Universidad Católica Luis Amigó, Cardona Zuleta Elvigia
Published: July 2021

En este libro se presenta una propuesta teórica y metodológica que aporta elementos pedagógicos y didácticos para la formación de estudiantes del pregrado de Derecho, desde un Enfoque de Equidad de Género para las Mujeres (EEGM). La investigación de la cual se deriva devela los estereotipos asociados al tema de las obligaciones alimentarias presentes en estudiantes y profesores, y resalta la importancia de prácticas interculturales, interseccionales y diferenciadas en la atención a los y las usuarias de demandas por alimentos que se tramitan en el Consultorio Jurídico Guillermo Peña Alzate de la Facultad de Derecho y Ciencias Políticas de la Universidad de Antioquia, sede Medellín, con la finalidad de que el estudiante, en su etapa de prácticas académicas, pueda utilizar diferentes instrumentos teóricos, convencionales, jurisprudenciales y normativos, enmarcados en los estudios culturales del derecho.
Green and Efficient Modification of Grape Seed Oil to Synthesize Renewable Monomers
Authors: Gaglieri Caroline , Alarcon Rafael , de Moura Aniele , Magri Raquel , da Silva-Filho Luiz , Bannach Gilbert
Published: July 2021

Grape seed is a waste product from the wine and juice industries. However, vegetable oil can be extracted from it, which is a renewable chemical with a huge potential application after chemical modifications, such as epoxidation and maleinization processes. This paper therefore deals with the use of grape seed oil, to produce its epoxidized and maleinized derivatives. Both derivatives were synthesized in order to improve the conversion (99.4%), yield (98.9%) and selectivity (99.5%) values, as well as to decrease the reaction time (3 h) using cleaner energy sources and heterogeneous catalysts, which can be used 4× without regeneration and obtaining similar conversion and yield values, and at least 5× keeping high selectivity. Based on the characterization results, both grape seed oil derivatives may be applied in different fields, including polymer chemistry as a monomer, coating, and paint. In addition, they can be an option to industries that use petrochemical derivatives as precursors.
Rural EFL Teachers’ Emotions and Agency in Online Language Teaching: I Will Survive
Authors: Sari Dini Rosita
Published: July 2021

This article explores rural English as a Foreign Language (EFL) teachers’ emotions and agency in online language teaching. Based on Hargreaves’s emotional geography framework, teachers’ emotions and teacher agency are both captured through teachers’ narration about their feelings, salient challenges that they encountered, and their coping strategies. Research data were collected using semi-structured interviews with two English teachers working in rural upper secondary schools in Nunukan, Indonesia. The collected data were analyzed with an inductive approach. The findings portray how rural EFL teachers experience various emotions which are mainly caused by physical and sociocultural distance, how agency helps these teachers with abilities to reflect on their feelings and to take crucial actions, and to what extend the need for immediate professional development programs to develop online teaching skills is.
Study on drought events in China based on time-varying nested Archimedean-copula function
Authors: Zhao Ziyang , Wang Hongrui , Shi Qiuyang , Wang Cheng
Published: July 2021

Drought forecasting, which can enable contingency actions to be implemented in advance of a drought, plays a significant role in reducing the risks and impacts of drought. In this study, a simulation framework of the occurrence probability of drought events based on a nested copula function and Gibbs sampling is proposed to effectively compensate for the high-dimensional problems and lack of initial data in traditional methods. Precipitation data of 718 meteorological stations from 1961 to 2018 in China was analyzed. The results showed that the occurrence location of drought events was mainly concentrated from 35° to 42° north latitude and 105° to 120° east longitude, with the occurrence time mainly concentrated from September to November. The Archimedean-copula function, constructed based on latitude, longitude, and occurrence time, could precisely determine the spatiotemporal joint probability distribution of drought events (RMSE: 0.01). The optimal time-varying nested Archimedean-copula functions were obtained from February to May (spring), June to September (summer) and October to January (autumn and winter). Compared with the nested Archimedean-copula function, the accuracy of Gibbs sampling and simulation based on the time-varying nested Archimedean-copula function was increased by 84.05% latitude and 69.76% longitude. The results provide an effective means for scientific drought forecasting, and water resource management departments can take preventive measures at an early stage.
Sharp Front analysis of moisture buffering
Authors: Hall Christopher , Lo Gloria J. , Hamilton Andrea
Published: July 2021

Moisture buffering describes the use of materials with high water-vapour sorption capacity to provide humidity control

in interior spaces. Established models of the moisture dynamics of buffering are derived from conventional Fickian vapour-diffusion

equations. We describe an alternative analysis using a Sharp-Front formulation. This yields a similar expression for the 

moisture effusivity, several consistent scalings and a new definition of the moisture penetration depth. Features of the model are compared with 

some published experimental data. A new sorption buffer index is a measurable experimental property that describes the water-vapour 

buffer strength of the material.
Experiences of an Online Treatment for Adolescents With Nonsuicidal Self-injury and Their Caregivers: Qualitative Study
Authors: Simonsson Olivia , Engberg Hedvig , Bjureberg Johan , Ljótsson Brjánn , Stensils Julia , Sahlin Hanna , Hellner Clara
Published: July 2021

Background

Nonsuicidal self-injury (NSSI) is common in adolescence and is associated with several adverse outcomes. Despite this, few established treatment options exist. Online treatment seems promising for several conditions; however, knowledge on NSSI is scarce. It is important to explore how online treatment for NSSI is experienced to improve such interventions and learn more about factors that are important in the treatment of adolescents with NSSI.

Objective

This study aims to explore the experiences of a novel online treatment for adolescents with NSSI and their caregivers.

Methods

A qualitative study using thematic analysis was conducted through semistructured interviews with 9 adolescents and 11 caregivers at treatment termination or at the 6-month follow-up of the online emotion regulation individual therapy for adolescents.

Results

A total of 3 overarching themes were identified. The theme support can come in different shapes showed how support could be attained through both interaction with the therapist as well as through the format itself (such as through the fictional characters in the material and the mobile app). Caregivers found it helpful to have their own online course, and adolescents accepted their involvement. The theme self-responsibility can be empowering as well as distressing showed that self-responsibility was highly appreciated (such as deciding when and how to engage in treatment) but also challenging; it caused occasional distress for some. The theme acquiring new skills and treatment effects showed the advantages and challenges of learning several different emotion regulation skills and that decreased emotion regulation difficulties were important treatment outcomes for adolescents. In addition, several different skills seemed to facilitate emotion regulation, and having access to such skills could hinder NSSI.

Conclusions

Online emotion regulation individual therapy for adolescents seems to offer an accepted way to deliver family interventions for this target group; facilitate skills training with several means of support, including support from both the mobile app and the therapist; contribute to decreasing emotion regulation difficulties and teaching skills that could hinder NSSI; and cause (in some individuals) distress because of the self-responsibility that is inherent to online formats, which needs to be addressed.
Infodemics on Youtube: Reliability of Content and Echo Chambers on COVID-19 (Preprint)
Authors: Di Marco Niccolò , Cinelli Matteo , Quattrociocchi Walter
Published: July 2021

UNSTRUCTURED

Social media radically changed how information is consumed and reported and elicited a disintermediated access to an unprecedented amount of content. The world health organization (WHO) coined the term infodemics to identify the information overabundance during an epidemic. Indeed, the spread of inaccurate and misleading information may alter behaviours and complicate crisis management and health responses. This paper addresses information diffusion during the COVID-19 pandemic period with a massive data analysis on YouTube. First, we analyze more than 2M users’ engagement in 13000 videos released by 68 different YouTube channels, with different political bias and fact-checking indexes. We then investigate the relationship between each user’s political preference and her/his consumption of questionable/reliable information. Our results, quantified using information theory measures, provide evidence for the existence of echo chambers across two dimensions represented by the political bias and by the trustworthiness of information channels. Finally, we observe that the echo chamber structure cannot be reproduced after properly randomizing the users’ interaction patterns.
IoT Based Smart Umbrella
Authors: K Karthik
Published: July 2021

Automatic sensor-based umbrella can be used during rainy, summer, snowfall and dense foggy seasons. It can be helpful not only to save the life of the cloth, street vegetables, fruits but in some situations also to save the human life. The idea is to design an umbrella that can be open and shut automatically with the help of NodeMCU programming. In present research work has come over with a smart rain sensing system that can detect the rain and opens up the umbrella’s link support. A raindrop sensing system is adding in this smart system, which gives a reading proportional to the amount of rain pouring on it. The smart system consists of a rack and pinion system, the rack is fixed to an umbrella such that when a sensor senses the exceeding value of rain drops, it gives a signal to the pinion attached to a motor. Then the motor starts rotating and the umbrella opens.
Multi Keyword Search on Encrypted Data with Ranking
Authors: Wahul Revati M
Published: July 2021

To maintain the anonymity of users, cloud storage owners often outsource encrypted documents. As a consequence, it is important to establish efficient and precise cypher text search techniques. One issue would be that the connection between documents is typically obscured during the encryption process, resulting in a significant deterioration of search accuracy efficiency. Additionally, the volume of data stored in data centers has exploded. This will make it significantly more difficult to create cipher text search schemes capable of providing efficient and reliable online information retrieval on large quantities of encrypted data. The paper proposes a hierarchical clustering approach in order to accommodate additional search semantics and to satisfy the demand for fast cipher text search in a big data environment. The proposed hierarchical approach clusters documents according to their minimum importance levels and then sub-clusters them until the maximum cluster size is reached. This approach can achieve linear computational complexity throughout the search process, spite of the fact that its size of the record set grows exponentially. The minimum hash sub-tree structure is used in this paper to check the validity of search results. The results demonstrate that as the number of documents in the dataset increases, the proposed method's search time increases linearly, while the conventional method's search time increases exponentially. Additionally, the suggested method outperforms the standard method in terms of rank privacy and document relevance.
Screening of Antibacterial Efficacy of Aloe Barbadensis Miller (Aloe Vera) Using Leaf Extract against Different Bacterial Strains
Authors: Singh Pravanchana
Published: July 2021

The current research was aimed to evaluate in vitro antibacterial activity of crude extract prepared from leaves of Aloe vera plant. The extract of Aloe vera was prepared in Methanol. Two extracts were prepared, one from whole leaf powder and the other from fresh Aloe vera gel. To determine the antibacterial efficacy of the given plant, Kirby-bauer disk diffusion method was performed. The standard antibiotic used was Gentamicin. Gentamicin showed significant antimicrobial efficacy against E.coli and Bacillus subtilis forming a zone of inhibition of 34mm in both. This research provides information about antibacterial susceptibility of aloe vera leaves (leaf powder and fresh gel) against two different bacteria: E.coli which is a gram-negative bacteria and Bacillus subtilis which is a gram-negative bacteria. The antibacterial susceptibility test showed that the extract of leaf and the gel of Aloe vera inhibited the growth of both microorganisms during test. Growth of E,coli strain were inhibited more as compared to Bacillus subtilis because gram negative bacteria do not have lipopolysaccharide layer in their cell wall. Also the fresh gel Extract was more effective as compared to Aloe vera leaf powder.
Seismic Analysis of RCC and Steel Building on Sloping Ground
Authors: Kadu Amruta
Published: July 2021

It is necessary to design and analyse a structure to perform well under seismic loads and also endow with well strength, stability and ductility for seismic design. The seismic performance of high rise steel frame and RCC frame structure is analysed by equivalent static method. The advancement in building, Information, modelling has integrated design, detailing, and fabrication of steel which will result in high performance under earthquake loading. In present work various models were analysed with the help of Staad pro. And the results so obtained were plotted and compared.
Smart Band for Monitoring Vitals for Elderly People in Quarantine
Authors: Karthiyayini J.
Published: July 2021

Corona virus disease 2019 (COVID-19) has emerged as a pandemic with serious clinical manifestations including death. A pandemic at the large-scale like COVID-19 places extraordinary demands on the world’s health systems, dramatically devastates vulnerable populations, and critically threatens the global communities in an unprecedented way. While tremendous efforts at the frontline are placed on detecting the virus, providing treatments and developing vaccines, it is also critically important to examine the technologies and systems for tackling disease emergence, arresting its spread and especially the strategy for diseases prevention. The objective of this article is to review enabling technologies and systems with various application scenarios for handling the COVID-19 crisis. The article will focus specifically on 1) wearable devices suitable for monitoring the populations at risk and those in quarantine, both for evaluating the health status of caregivers and management personnel, and for facilitating triage processes for admission to hospitals; 2) unobtrusive sensing systems for detecting the disease and for monitoring patients with relatively mild symptoms whose clinical situation could suddenly worsen in improvised hospitals; and 3) telehealth technologies for the remote monitoring and diagnosis of COVID-19 and related diseases. Finally, further challenges and opportunities for future directions of development are highlighted.
Design and Analysis of Vehicle Mine Blast Using AUTODYN
Authors: Prasad V. Vara
Published: July 2021

Anti-vehicular (AV) mines are capable of disabling a heavy vehicle, or completely destroying a lighter vehicle. The most common form of AV mine is the blast mine, which uses a large amount of explosive to directly damage the target. In a conventional military setting, landmines are used as a defensive force-multiplier and to restrict the movements of the opposing force. They are relatively cheap to purchase and easy to acquire, hence landmines are also potent weapons in the insurgents’ armamentarium. The stand-off nature of its design has allowed insurgents to cause significant injuries to security forces in current conflicts with little personal risk. As a result, AV mines and improvised explosive devices (IEDs) have become the most common cause of death and injury to Coalition and local security forces operation. A number of different strategies are required to mitigate the blast effects of an explosion. Primary blast effects can be reduced by increasing the standoff distance between the seat of the explosion and the crew compartment. Enhancement of armour on the base of the vehicle, as well as improvements in personal protection can prevent penetration of fragments. Mitigating tertiary effects can be achieved by altering the vehicle geometry and structure, increasing vehicle mass, as well as developing new strategies to reduce the transfer of the impulse through the vehicle to the occupants. Protection from thermal injury can be provided by incorporating fire resistant materials into the vehicle and in personal clothing. The challenge for the vehicle designer is the incorporation of these protective measures within an operationally effective platform.
Blockchain based Digital Storage System
Authors: Bhardwaj Axat
Published: July 2021

The ideа is tо соnstruсt а рlаtfоrm whiсh аllоw the рeорle tо stоre their legаl identifiсаtiоns withоut the feаr оf identifiсаtiоn theft. The рeорle using this рlаtfоrm will hаve соmрlete соntrоl оn the infоrmаtiоn they wаnt tо shаre оr nоt. Identity theft is the deliberаte use оf sоmeоne else's identity, usuаlly аs а methоd tо gаin а finаnсiаl аdvаntаge оr оbtаin сredit аnd оther benefits in the оther рersоn's nаme, аnd рerhарs tо the оther рersоn's disаdvаntаge оr lоss. The рersоn whоse identity hаs been аssumed mаy suffer аdverse соnsequenсes, esрeсiаlly if they аre held resроnsible fоr the рerрetrаtоr's асtiоns. Identity theft оссurs when sоmeоne uses аnоther's рersоnаlly identifying infоrmаtiоn, like their nаme, identifying number, оr сredit саrd number, withоut their рermissiоn, tо соmmit frаud оr оther сrimes. Identity thefts hаve inсreаsed exроnentiаlly in this erа оf digitаlizаtiоn. Using this рlаtfоrm, nоt оnly the рeорle will hаve best in сlаss рrоteсtiоn but аlsо full аuthоrity оn whаt infоrmаtiоn shоuld be shаred аnd оn whiсh рlаtfоrm.
On Preconditions for Ibn Khaldun’s Philosophy of History
Authors: Nasyrov I. R.
Published: July 2021

This article is devoted to the study of the preconditions for Ibn Khaldun’s philosophy of history. It is argued that his theory of history was both a result of his own intellectual development and previous theories. The author states that Ibn Khaldun was inﬂuenced by ancient thought, political culture of Western Asia and Islamic intellectual tradition. The ﬁrst was Ancient Greek philosophy and medicine that he inherited from the great physicians and philosophers like Aristotle, Hippocrates and Galen. The second was cultural and political legacy of Sassanid Persia. The third prerequisite for formation of Ibn Khaldun’s theory of history was the adoption of the achievements of his predecessors, Islamic scientists, theologians and philosophers who had contributed to the rational critique of history.
THE FORMULATION OF PEEL-OFF MASK FROM THE ETHANOL EXTRACT OF BILIMBI LEAVES (Averrhoa blimbi L.) AS ANTI-ACNE TREATMENT
Authors: Zarwinda Irma , Fauziah Fauziah , Jumirna Jumirna , Adriani Azmalina
Published: July 2021

This research aims to formulate and assess the efficacy of the peel-off mask as an anti-acne of ethanol extract from bilimbi leaves (Averrhoa bilimbi L.).  The method used was an experiment, evaluating the extract through the inhibition test of Staphylococcus epidermis bacteria with the paper disk diffusion method. The peel-off mask formulation added the extract with a concentration of 7% (F1), 9% (F2), 11% (F3), and without using extract (F0). The Peel-off mask preparation testing includes the detection of scents, colours, irritation checks, and the determination of peel-off anti-acne mask efficacy. This study was carried out at Akafarma of Banda Aceh and the Chemistry laboratory of FKIP Unsyiah. The findings of the inhibition zone for Staphylococcus epidermis bacteria at extract concentrations of 100%, 75%, 50% and 25% were 15 mm, 12 mm, 11 mm and 10 mm, respectively. The four peel-off mask formulas were gel, homogeneous, brown, with the distinctive scent of bilimbi leaves, and did not irritate the volunteers’ skin. The average decline in acne before and after using the mask for any formula (F0, FI, FII, and FIII) was 19.64%, 22.63%, 28.75% and 50%, respectively. The peel-off mask of ethanol extract of bilimbi leaves (Averrhoa bilimbi L.) is effective as an anti-acne treatment.
Assessing Risk and Knowledge of Women on Breast Cancer and Providing Lifestyle Advice for the Management of Breast Cancer Risk
Authors: Ishrar Shaik Mohammad Ghouse  , Neeluri Prasanth  , GaddiGeetha Reddy  , Madamanchi Ganga Manasa
Published: July 2021

Breast cancer is the most common cancer and is the main cause of cancer mortality among women in the world. Overall, 1 in 28 women is likely to develop breast cancer during her lifetime. Although the mortality rate is decreasing, the incidence is persistently increasing due to urbanization and lifestyle changes. So, there is a need to assess the personal breast cancer risk and increase the knowledge of women on early detection. The present study aims to assess the risk and knowledge of women on breast cancer. The main objective of the study is to identify the women at high risk, to create awareness among women about early screening and detection and to educate lifestyle management to decrease breast cancer risk. A descriptive cross-sectional study was performed during the period of June 2019 to November 2019 in the women attended for mammographic examination. A total of 270 women responded to the study. The results showed that five-year risk is found to be high for 31.1% of women and low for 68.8% of women with a mean of 1.4 and the standard deviation is 1.24. About 14.81% of women were found to have strong lifetime risk and 30.37% of women had average lifetime risk and 54.81% women had usual lifetime risk. The mean lifetime risk of the women is 16.09 and the standard deviation is 10.2.  The majority of the participants have low knowledge on breast cancer; BSE, and mammography i.e., 80% of them were lack of knowledge. The mean knowledge score is 6.34 and the standard deviation is 5.45. The women who had high five-year and strong lifetime risk are eligible for breast cancer prevention and management approaches. The women with moderate lifetime risk were advised with regular screening and Breast Self-Examination practices.
Kecukupan Gizi, Pengetahuan, dan Anemia Ibu Hamil
Authors: Ghiffari Eugidia Mayang , Harna Harna , Angkasa Dudung , Wahyuni Yulia , Purwara Lintang
Published: July 2021

Selama masa kehamilan, terjadi pertumbuhan dan perkembangan janin menuju masa kelahiran. Salah satu masalah gizi yang sering terjadi selama kehamilan adalah anemia. Menurut data Riskesdas tahun 2013 prevalensi anemia kehamilan sebesar 37,1% dan mengalami peningkatan pada 2018 menjadi 48,9%. Penelitian ini bertujuan untuk menganalisa hubungan tingkat kecukupan gizi (protein, zat besi, asam folat, vitamin B12, dan vitamin C) dan tingkat pengetahuan tentang anemia dengan kejadian anemia pada ibu hamil. Penelitian ini menggunakan desain penelitian cross sectional dengan melibatkan 50 ibu hamil trimester II dan III di Puskesmas Kecamatan Kebon Jeruk sebagai responden dengan pengambilan sample melalui teknik purposive sampling. Uji statistik yang digunakan adalah uji chi square dengan menggunakan alternatif fisher’s exact test. Hasil penelitian ini menunjukan bahwa sebanyak 4% ibu hamil  mengalami anemia . Sebagian besar memiliki tingkat asupan zat besi, asam folat, dan vitamin C yang kurang, serta tingkat pengetahuan tentang anemia pada ibu hamil yang cukup. Hasil analisis bivariat menunjukan tidak terdapat hubungan yang signifikan antara tingkat kecukupan gizi (protein, zat besi, asam folat, vitamin B12, dan vitamin C) dengan kejadian anemia (pvalue>0,05) dan tidak terdapat hubungan yang signifikan antara tingkat pengetahuan tentang anemia dengan kejadian anemia (p=1,000)  . Sehingga dapat disimpulkan bahwa tidak terdapat hubungan antara tingkat kecukupan gizi dan tingkat pengetahuan anemia dengan kejadian anemia pada ibu hamil. Saran dalam penelitian ini adalah ibu hamil sebaiknya memperhatikan kecukupan zat gizi yang baik selama kehamilan (protein, zat besi, asam folat, vitamin B12, dan vitamin C), serta menambah pengetahuan mengenai anemia untuk mencegah kejadian anemia.
Pengaruh Ekstrak Buah Jamblang Terhadap Kadar Antosianin, Aktivitas Antioksidan Dan Sifat Organoleptik Es Krim Ubi Ungu
Authors: Anggara Ramzy Arif Satriyo Bima , Fauziyah A’immatul , Ilmi Ibnu Malkan Bakhrul
Published: July 2021

International Diabetes Federation (IDF) menyatakan bahwa pada tahun 2013, Diabetes Mellitus (DM) tipe 2 menyerang 382 juta orang. Buah jamblang memiliki kandungan fenolik yang tinggi untuk memperbaiki kondisi DM Tipe 2. Penelitian ini bertujuan untuk menganalisis pengaruh ekstrak buah jamblang terhadap penerimaan sensori, kandungan antosianin, dan aktivitas antioksidan es krim ubi jalar ungu. Rancangan penelitian ini adalah eksperimen dengan rancangan acak lengkap dengan dua ulangan pada setiap formula. Terdapat 3 level buah jamblang pada es krim ubi jalar ungu yaitu Formula 1 sebanyak 30%, Formula 2 sebanyak 40%, Formula 3 sebanyak 50%. Uji organoleptik menunjukkan bahwa esktrak buah jamblang pada es krim ubi jalar ungu meningkatkan penerimaan warna secara signifikan (p<0,005). Ekstrak buah jamblang pada es krim ubi jalar ungu meningkatkan aktivitas antosianin dan antioksidan secara signifikan (p<0,05). Formula terbaik adalah F3 dengan kandungan energi, kadar air, karbohidrat, protein, lemak, abu 52 kkal; 87%; 9,6%, 1,83%; 0,72%; 0,39%.
Pengaruh Penambahan Bit Merah Terhadap Total Fenol, Aktivitas Antioksidan, dan Organoleptik Puding Rumput Laut
Authors: Luga Ezra , Fauziyah A’immatul , Ilmi Ibnu Malkan Bakhrul
Published: July 2021

Diabetes melitus (DM) merupakan salah satu penyakit metabolik yang dapat memicu terbentuknya senyawa radikal bebas dalam tubuh. Bit merah merupakan salah satu bahan pangan yang mengandung total fenol yang dapat menimbulkan aktivitas antioksidan yang berguna untuk meredam senyawa radikal bebas. Tujuan penelitian ini untuk menganalisis pengaruh penambahan sari bit merah terhadap total fenol, aktivitas antioksidan, dan sifat organoleptik pada puding rumput laut serta menentukan formula terpilih, dan mengetahui kandungan zat gizi pada formula terpilih. Penelitian ini merupakan eksperimental dengan desai penelitian Rancangan Acak Lengkap (RAL) satu faktor dengan dua kali pengulangan. Faktor tersebut adalah formula puding rumput laut yang dibedakan menjadi 3 dengan masing-masing tingkat persentase penambahan sari bit merah sebesar F1 (55%), F2 (60%), dan F3 (65%). Analisis uji organoleptik menggunakan uji Kruskal Wallis dan dilanjutkan dengan uji Mann Whitney. Analisis pada aktivitas antioksidan dan total fenol menggunakan Anova dan jika terdapat perbedaan dilanjutkan uji Duncan. Hasil analisis menunjukkan bahwa tingkat penambahan sari bit merah berpengaruh nyata (p=0,000) terhadap tingkat kesukaan panelis pada parameter rasa, serta berpengaruh nyata pada total fenol (p<0,05) namun tidak berpengaruh nyata pada aktivitas antioksidan (p>0,05). Formula terpilih adalah puding rumput laut F3 dengan penambahan sari bit merah (65%) yang memiliki kadar air sebesar (91,05%), kadar abu (1,17%), kadar karbohidrat (5,91%), kadar protein (1,25%), kadar lemak (0,73%), aktivitas antioksidan ( 19023,32 ppm), dan kadar total fenol (42,3 ± 0,7071 mg GAE/100 gram).
Pengaruh Penambahan Bekatul Terhadap Kadar Serat, Aktivitas Antioksidan dan Sifat Organoleptik Minuman Kedelai
Authors: Shafitri Nurlitta , Fauziyah A'imatul , Puspareni Luh Desi , Nasrulloh Nanang
Published: July 2021

Hiperkolesterol merupakan kondisi kadar kolesterol dalam darah melebihi batas normal (>240 mg/dl). Salah satu alternatif pencegahan hiperkolesterol adalah dengan meningkatkan asupan serat dan antioksidan. Bekatul merupakan jenis pangan tinggi serat dan kaya antioksidan. Kedelai merupakan jenis pangan tinggi isoflavon yang mampu menurunkan hiperkolesterol. Penelitian ini bertujuan untuk menganalisis pengaruh penambahan bekatul terhadap kadar serat, aktivitas antioksidan dan sifat organoleptik minuman kedelai serta menentukan formula terpilih dan menganalisis kandungan gizi formula terpilih. Desain penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) satu faktor berupa empat perlakuan dengan penambahan bekatul sebesar F0 (0%), F1 (6%), F2 (8%) dan F3 (10%). Analisis uji organoleptik menggunakan uji Kruskal Wallis dan dilanjutkan dengan uji Mann Whitney jika terdapat perbedaan. Analisis serat pangan dan aktivitas antioksidan menggunakan uji ANOVA dan dilanjutkan dengan uji Duncan jika terdapat perbedaan signifikan. Hasil analisis uji organoleptik menunjukkan bahwa penambahan bekatul berpengaruh nyata (p<0,05) terhadap tingkat kesukaan panelis pada parameter warna, aroma, tekstur dan rasa minuman kedelai. Hasil analisis serat pangan dan aktivitas antioksidan menunjukkan bahwa penambahan bekatul berpengaruh nyata (p<0,05) terhadap kadar serat pangan dan aktivitas antioksidan minuman kedelai. Formula terpilih pada penelitian ini adalah F3 dengan penambahan bekatul 10% karena memiliki kandungan gizi yang lebih unggul dibanding formula lain, yaitu kadar serat pangan 10,23 gram, aktivitas antioksidan 3094.18 ppm, kadar protein 1,80%, kadar lemak 1,64%, kadar karbohidrat 6,49%, kadar abu 0,73% dan kadar air 89,34%.
Utilización de Leucaena leucocephala en el levante de ovinos africanos en el Piedemonte Llanero, Colombia
Authors: Leguizamón L.A. , Pérez C.A. , Roa Vega María Ligia
Published: July 2021

El objetivo de este proyecto fue evaluar la L. lecucephala como suplemento en ovinos de levante en pastoreo. Se utilizaron 12 machos tipo africano (sudaneses), peso promedio de 14.45 Kg, con una dieta base de B. decumbens, los ovinos se distribuyeron completamente al azar tres repeticiones y cuatro tratamientos: T1: (testigo) braquiaria, T2: braquiaria más el 1% del peso vivo del animal, en materia seca de leucaena (MSL), T3: braquiaria, 1.5% de MSL y T4: braquiaria más el 2.0% de MSL. Los ovinos se mantuvieron en franjas divididas con cerca eléctrica y diariamente se rotaban. Los pesajes se tomaron cada 7 días durante los dos meses. Para las pruebas de digestibilidad, se utilizaron cuatro ovinos machos, peso promedio de 15 kilos y se estabularon en jaulas metabólicas, se les suministraron los mismos tratamientos para evaluar la digestibilidad in vivo. Al pasto braquiaria y a la leucaena se les realizaron análisis proximal (materia seca proteína, grasa, fibra cruda, cenizas) y determinación de fibra detergente neutro (FDN) y fibra detergente ácido (FDA). A las excretas recolectadas también se realizaron los mismos análisis de los forrajes, se calcularon los coeficientes de digestibilidad (COD) y los nutrientes digestibles totales (NDT). El contenido de proteína de la leucaena es de 19.3%, mientras que la del pasto es de 8.5%, es 2.29 veces más la de la leguminosa comparada con la del pasto. Las digestibilidades de MS y proteína fueron superiores (P>0.05) en los tratamientos T3 y T4, con relación a los otros dos. Las ganancias de peso total y diaria fueron superiores (P>0.05) para T3 seguido de T4 y T2 que son mayores (P>0.05) a T1. Los consumos de MS fueron más elevados (P>0.05) en T1 y T4 con relación a T3 y T2. La mejor conversión alimenticia (P>0.05) sobre el consumo de MS fue para T3 seguido de T2, T4 y T1. Indudablemente, utilizar la leucaena para la alimentación de rumiantes como suplemento de una gramínea es ventajoso porque su contenido nutricional le permite ofrecer una dieta balanceada al animal sin detrimento de sus índices productivos, sobre todo en zonas donde los forrajes son de baja calidad.
Efecto de la “tierra de diatomeas”, como antiparasitario en una ganadería lechera en el Piedemonte Llanero
Authors: Lozada Monroy Hernando , Gutiérrez A. , Soto P.
Published: July 2021

Las enfermedades parasitarias han sido una de las mayores preocupaciones en el subsector pecuario de Colombia, razón por la cual las entidades como: ICA, CORPOICA, CEISA y CEGA entre otras, han realizado y publicado diferentes investigaciones sobre los daños causados a nivel sanitario y económico. Por otra parte, la producción animal en el Departamento del Meta está dominada por la ganadería vacuna, “casi un 90% del valor de la producción pecuaria corresponde a esta ganadería (Cámara de Comercio 2008), aunque en el Piedemonte la tendencia es hacia el doble propósito; del Departamento del Meta salen diariamente con destino a la industria láctea del centro del país, aproximadamente 50 mil litros de leche cruda, (Arias, 2009). En la constante búsqueda de nuevas alternativas que permitan obtener productos de calidad sin la presencia de residuos de fármacos y/o sustancias químicas en los productos de origen animal, se ejecutó la presente investigación, utilizando vacas destinadas a la producción láctea a las cuales se suministró un producto natural conocido como “Tierra de diatomeas” al cual se le atribuyen beneficios en el control de parásitos internos y externos en animales.La evaluación del producto se llevó a cabo en la finca “El rancho de San José”, la cual se encuentra aproximadamente a dos (2) horas de la capital del Departamento del Meta, en la vereda Alta cal, zona rural del municipio de El Castillo. Se escogieron de forma aleatoria treinta (30) vacas lecheras del cruce Pardo Suizo x Jersey, y algunas Holstein, para conformar tres (3) grupos experimentales, cada uno con diez (10) animales. Con intervalos de cuarenta y cinco (45) días, se tomaron datos en cuatro (4) oportunidades, sobre el grado de infestación por parásitos externos, así como muestras para coprología y hematología. Complementariamente se tomaron muestras grupales para determinar la calidad fisicoquímica de la leche, con el propósito de registrar las posibles variaciones en sus características, a lo largo del tiempo.