bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating facilitators and barriers to the routine provision of HIV PrEP in community pharmacies in London
Authors: Alter Marsha , Lakhani Shivali , Alaa Aos , Karki Manisha , Riboli-Sasco Eva , El-Osta Austen
Published: February 2025

Background

The United Kingdom’s (UK) integration of Pre-exposure Prophylaxis (PrEP) into community pharmacies presents an alternative avenue for supporting Human Immunodeficiency Virus (HIV) prevention. Despite its effectiveness, PrEP's accessibility remains hindered by various barriers within community settings. The aim of this study was to explore the perspectives of pharmacy team members regarding the barriers and facilitators to the routine provision of PrEP in community pharmacies in the UK, as well as any recommendations for mitigating these challenges.

Methods

Exploratory mixed-method cross-sectional study utilising an online survey and semi-structured interviews with community pharmacists and non-pharmacist team members across the North Thames area of London, England.

A convenience sample of 110 pharmacy team members participated in the study, including both pharmacists and non-pharmacists. Two pharmacy technicians and eight pharmacists took part in semi-structured interviews.

Data collection involved a cross-sectional online survey and semi-structured interviews. The survey collected data such as demographic characteristics, knowledge, and attitudes towards PrEP provision, while interviews explored in-depth perceptions, experiences and recommendations.

Results

A significant proportion of respondents expressed a lack of confidence and knowledge regarding PrEP, with training identified as a critical need for facilitating PrEP provision. Additionally, the study highlighted the potential of community pharmacies to increase accessibility of PrEP due to their geographical reach and the trust placed in pharmacists.

Conclusion

The study demonstrates an interest from community pharmacies in London in providing a commissioned PrEP supply service. However, this would need to be in conjunction with training programmes and public health campaigns to equip community pharmacies for effective PrEP provision. Enhancing pharmacists' competencies and raising public awareness could significantly support the current HIV prevention strategies in the UK.
Subnational tailoring of malaria interventions to prioritize the malaria response in Guinea
Authors: Diallo Ousmane Oumou , Diallo Abdourahamane , Toh Kok Ben , Diakité Nouman , Dioubaté Mohamed , Runge Manuela , Symons Tasmin , Diallo Elhadj Marouf , Gerardin Jaline , Galatas Beatriz , Camara Alioune
Published: February 2025

Background

In the context of high malaria burden yet limited resources, Guinea’s national malaria programme adopted an innovative subnational tailoring (SNT) approach, including engagement of stakeholders, data review, and data analytics, to update their malaria operational plan for 2024–2026 and identify the most appropriate interventions for each district considering the resources available.

Methods

Guinea’s malaria programme triggered the SNT exercise with a list of decisions that could be informed with local data. The programme established an SNT team, which determined intervention targeting criteria; identified, assembled, and reviewed relevant data sources; stratified malaria risk and its determinants to inform geographical targeting for each intervention; and used mathematical modelling to predict the impact of different intervention mix scenarios. The SNT analysis was performed at the district level, excluding the urban area of Conakry.

Results

Malaria incidence, malaria prevalence, and all-cause under-5 mortality were used for the epidemiological stratification of Guinea. Additional indicators relevant for decision-making including seasonality patterns, insecticide resistance, historical malaria interventions and vaccine coverage were also stratified. Stratified layers were used to inform the targeting criteria for each intervention to identify districts to prioritize for indoor residual spray, dual-action insecticide-treated nets, seasonal malaria chemoprevention (SMC), including number of cycles for each eligible district, malaria vaccine, and perennial malaria chemoprevention. Results of the SNT analysis were used to mobilize funding from the Global Fund for scale-up of dual-action nets and expansion of SMC.

Conclusions

SNT allowed Guinea’s national malaria programme to adapt their intervention strategy at the health district level, an unprecedented approach in the country. The use of local data to inform eligibility and prioritization allowed the programme to identify the optimal mix of interventions for each district and to successfully mobilize resources to support their plans.
Whole genome uniparental isodisomy detected using single nucleotide polymorphism (SNP) microarray in molar pregnancy: a case report
Authors: Okonkwo Onyinye O. , Ortega Veronica , Kane Sheila , Aldrete Galina , Ramirez Paulina , Valente Philip T. , Velagaleti Gopalrao V.N.
Published: February 2025

Background

Gestational trophoblastic neoplasms consist of complete and partial hydatidiform moles, both of which are considered aberrant conceptuses. Both conditions, complete hydatidiform mole (CHM) and partial hydatidiform mole (PHM), differ in histological characteristics, genetic origin and content and clinical features. CHM have a diploid karyotype, mostly 46,XX but lack maternal genetic contribution with all chromosomes of paternal origin. High-resolution SNP microarray testing is an efficient method used to determine the parental contribution of the genomic material in molar pregnancies and confirm the diagnosis.

Case presentation

We present a case of CHM in a 43-year-old, G3P2Ab1 who presented to the emergency department with 2 episodes of heavy bleeding. Chromosome analysis showed a normal 46,XX karyotype but with a homozygous pericentric inversion on chromosome 9. High-resolution SNP microarray studies detected whole genome uniparental isodisomy.

Conclusion

We present a case of CHM with homozygous pericentric inversion on chromosome 9 and whole genome uniparental isodisomy. This case illustrates the efficacy of high-resolution SNP microarray in confirming the diagnosis of CHM.
Roles of mediodorsal thalamus in observational fear-related neural activity in mouse anterior cingulate cortex
Authors: Ramesh Kritika , Nair Indrajith R. , Yamamoto Naoki , Ogawa Sachie K. , Terranova Joseph I. , Kitamura Takashi
Published: February 2025

Observational fear (OF) is the ability to vicariously experience and learn from another’s fearful situation, enabling adaptive responses crucial for survival. It has been shown that the anterior cingulate cortex (ACC) and basolateral amygdala (BLA) are crucial for OF. A subset of neurons in the ACC is activated when observing aversive events in the demonstrator, which elicits OF. However, the neural circuit mechanisms underlying the expression of OF-related activity in the ACC remain unexplored. Previous studies have shown that the mediodorsal thalamus (MD) is crucial for OF, and MD neurons project to the ACC. Therefore, we hypothesize that the projection from MD to ACC may facilitate the OF-related activity in the ACC. By utilizing in vivo calcium imaging combined with the optogenetic terminal inhibition of MD-ACC pathway, we found that a subset of ACC neurons was activated when observing demonstrator’s fearful situation in male mice. Furthermore, the optogenetic inhibition of the MD-ACC projection during the demonstrator’s aversive moments significantly suppressed the OF-related activity in the ACC. Our data suggests that the MD-ACC projection plays a role in OF-related activity in ACC neurons.
Knowledge and management of Münchausen’s Syndrome by proxy: a survey conducted through the compilation of a questionnaire by pediatricians belonging to the Italian Society of Pediatrics
Authors: Nardello Rosaria , Cordova Giada , Spina Corinne La , Piro Ettore , Serra Gregorio , Corsello Giovanni , Argo Antonina
Published: February 2025

Background

Munchausen syndrome by proxy represent forms of abuse with long-term psychiatric outcomes. Since the prevalence of Munchausen Syndrome by proxy is uncertain and underestimated, this study aimed to investigate and analyze the phenomenon through the compilation of an anonymous questionnaire that explores the knowledge of the phenomenon and above all its management.

Methods

the study was conducted by sending an anonymous questionnaire to pediatricians who are part of the Italian Society of Pediatrics. The questionnaire consists of 18 multiple choice questions and was completed by 511 professionals.

Results

The main results highlighted that the majority of doctors knows Münchausen Syndrome by proxy. However, when there is a strong suspicion of the syndrome, they mostly seek discussion with the parent or with another specialist instead of referring to the competent authorities.

Conclusions

starting from the consideration that timely diagnosis is fundamental for the protection of the child, we emphasize the urgency of enhancing the recognition and management of Munchausen Syndrome by Proxy. Early diagnosis, appropriate reporting, and collaboration with child protection authorities are essential in safeguarding the well-being of vulnerable individuals.
Effect of Self-reported Physical Activity on Glycaemia and Blood Pressure in Healthy Participants from Bissau: A Cross-sectional Study
Authors: Sanca Lilica , Có Cipriano , Namara Nelson , Lopes Aladje , Emanuel Albino , Oliveiros Bárbara , Byberg Stine , Bjerregaard-Andersen Morten , Carvalho Eugénia , Massart Alain , Teixeira Ana
Published: February 2025

Background

Recent data show a dramatic increase in non-communicable diseases in developing countries, including cardiovascular disease, obesity and diabetes. Most of these diseases may be preventable and to some extent treatable by alterations in physical activity. We investigated the correlations of physical activity levels, according to energy expenditure [measured in metabolic equivalent minutes per week (METs x min/week)] with fasting glycaemia levels, blood pressure, body compositions and anthropometric variables in participants from Bissau, Guinea-Bissau.

Method

The International Physical Activity Questionnaire was used to assess levels of physical activity, by calculating METs x min/week. These were subsequently divided into low, moderate or high physical activity categories in a healthy group of participants. Fasting glucose, arterial blood pressure, body mass index and body fat were also assessed. Data was analyzed using the SPSS statistical software.

Results

429 participants were included from sports and health facilities around the country. Of these, 187 were highly active (> 3000 MET × min/ week or at least 1500 METs × min/week) and had a mean age of 26.8 ± 7.5 years. 76% (327/429) were male and 24% were female (102/429). The mean energy expenditure was 4866.7 ± 1241.2 METs × min/week and the mean fasting glucose was 94.0 ± 14.1 mg/dl. 4.1% (18/429) of the participants had diabetes and 12.8% (55/429) had hypertension. A significant negative correlation was found between blood glucose and total physical activity (rs = − 0.117, p = 0.015). Sedentary participants had the highest proportion (5.1%) of diabetes and higher rates of hypertension (15.8%). These participants had the highest obesity (10.1%) and overweight prevalence (23.7%). In addition, they also presented the highest percentage (5.1%) of body fat, with 55% of them showing high or very high visceral fat% content. In the sedentary group, a significant positive correlation, was found, indicating a low moderate association, between systolic blood pressure and weekly sitting time, rs(175) = 0.205, p = 0.006.

Conclusion

While high levels of physical activity had a significant impact on glycaemia control, physical activity had no significant impact on blood pressure. However, weekly sitting time may increase blood pressure.
Translation and Validation of the Portuguese Version of the Rating-of-Fatigue Scale
Authors: Barreira João , Brito João , Nakamura Fábio Yuzo , Figueiredo Pedro
Published: February 2025

Background

The Rating-of-Fatigue (ROF) scale is a validated tool to measure changes in perceived fatigue in sports and everyday contexts; thus, this study aimed to translate and validate the Portuguese version of the ROF scale. For this, the study was composed of three phases. Phase 1 involved a comprehensive translation of the ROF scale into Portuguese, followed by a back-translation and a consolidation process to obtain the final version of the ROF scale in Portuguese. In phase 2, the face validity of the scale was assessed. Seventy-three native Portuguese speakers responded to a series of Likert scale items designed to evaluate the purpose of the scale and assess whether it accurately measured the intended construct. In the final phase, the convergent and divergent validity of the scale was assessed during an incremental cycling test to exhaustion, followed by 10 min of passive recovery and a subsequent repetition of the initial 5 min of the test. The study was conducted between October 2023 and June 2024 in Portugal.

Results

The results from phase 1 indicated a high level of comparability and interpretability between the original and back-translated versions, with only minor adjustments made to finalize the Portuguese version of the ROF scale. In phase 2, a high level of face validity was observed. The median score for the item “measures fatigue” was (median [IQR]) was 3.0 [3.0, 4.0] out of 4. After participants were provided with the scale instructions, the face validity score improved significantly (4.0 [3.0, 4.0]; p = 0.001). In phase 3, during the incremental test, very large correlations were observed between ROF, and key physiological and performance indicators, including rating of perceived exertion (RPE), heart rate, oxygen consumption, and power output. Discriminant validity between ROF and RPE was found during the recovery.

Conclusions

The present study indicates that the Portuguese version of the ROF maintains the properties of the original version and can be used effectively in the Portuguese language.
International student mobility, Covid-19, and the labour market: a scoping review
Authors: Mihut Georgiana , Cullinan John , Flannery Darragh , Palcic Donal , Souto-Otero Manuel , Wiers-Jenssen Jannecke , Anabo Icy Fresno , Kasza Georgina , Perez-Encinas Adriana , Bin Qushem Umar
Published: February 2025

The Covid-19 pandemic resulted in significant disruptions to both international student mobility and labour markets. Against this background, this scoping review documents findings from 35 studies, published between January 2020 and February 2024, that focused on international student mobility, Covid-19, labour market outcomes, and related regulations. The review shows that the Covid-19 pandemic negatively impacted (1) the labour market outcomes of international students before studying abroad, through changes in visa regulations, (2) skill acquisition during their mobility, (3) the duration of their studies, and (4) the availability of jobs during and after their mobility period. These negative impacts occurred at a time when international students’ needs for work were heightened. This ‘double whammy’ was more pronounced among international students from lower socio-economic backgrounds, increasing pre-existing inequalities. It was also affected by students’ residency status and policy changes. These findings underline the critical role that temporality plays in shaping the returns to international student mobility. However, the existing literature on the topic is relatively sparse and has primarily relied upon qualitative approaches and rapid research. Future studies are needed to better understand the impact of Covid-19 on the labour market outcomes of international students.
Glycemic, Cardiorenal, and Weight Implications on Noninsulin Pharmacotherapy for the Management of Type 2 Diabetes
Authors: Fetzner Jillian , Rafi Ebne
Published: February 2025

Context

The incidence of diabetes is growing at an alarming rate globally. Most of these projected individuals will develop type 2 diabetes (T2DM), raising their risk of cardiovascular disease and chronic kidney disease. This mini-review examines current noninsulin and noninjectable pharmacotherapy focused in T2DM, highlighting the effect on glycemic control and importance of cardiovascular and renal outcomes.

Evidence acquisition

We included population level data and searched the PubMed database for recent systematic reviews, meta-analyses, and original research articles.

Evidence synthesis

There is a pharmacologic menu of noninsulin-based medications for the treatment of diabetes. Through varying mechanisms, all agents ultimately lead to glycemic improvement to varying degrees. Only a select number of agents are shown to improve important clinical cardiovascular and renal outcomes. Of note, sodium-glucose cotransporter-2 inhibitors have improved cardiovascular mortality and time to dialysis in people with diabetes. Likewise, incretin-based therapies have improved important cardiovascular and renal composite outcomes in those with diabetes and cardiovascular disease. As a result, agents with proven cardiovascular and renal benefits should be prioritized based on patient risk.

Conclusion

Despite the availability of new medications and technology, published clinical guidelines, and treatment algorithms, most people with diabetes remain above glycemic targets. We encourage clinicians to follow the guidelines and use appropriate medications to lower cardiovascular risk, delay progression of chronic kidney disease, reach glycemic targets, and manage weight.
A Poetics of Postmourning
Authors: Ramazani Jahan
Published: February 2025

Whereas the historical trauma of the Middle Passage and enslavement has been a prominent subject of Caribbeanist scholarship, there is surprisingly little sustained consideration of how poems and other imaginative works mourn this violent past, even though melancholic grief is a crucial component of the literary response. Building on the concepts of “postmemory” and “rememory,” this essay proposes the concepts of postmourning for the representation of transgenerational grief and remourning for its embodied enactment in creative work. Elegies exemplify the poetic response to both the historical losses of transatlantic slavery and to intimate, recent losses shadowed by this primordial, collective grief. Poets such as Dennis Scott and Lorna Goodison Caribbeanize elegy by drawing on rituals, songs, spiritual discourses, music, and other collective or “folk” vehicles of ancestral memory and shared ur-grief, combining them with the idiosyncrasy and aesthetic self-reflexivity of lyric, ars poetica, and writerly technique.
Régine Jean-Charles’s Black Feminist Ethical Reading of Twenty-First-Century Haitian Women’s Fiction
Authors: Dougé-Prosper Mamyrah A.
Published: February 2025

Looking for Other Worlds: Black Feminism and Haitian Fiction (2022) by Régine Jean-Charles engages scholarship across multiple disciplines and fields—Haitian studies, Caribbean studies, Black feminist studies, media studies, ecofeminism, anthropology, geography, and history—and employs diverse methods that include archival research, social media and artwork analysis, and literary critique. This review essay posits that Jean-Charles uses Black feminism rather than Haitian feminism, arguing for a Black feminist project that is transnational and global and that allows for both/and. Jean-Charles’s analyses of the works of Évelyne Trouillot, Yanick Lahens, and Kettly Mars focus on the ways these writers creatively deal with issues of gender, race, color, class, sexuality, Vodou, and nature. Yet despite her recognition of the impact of political crises on their novels’ characters, Jean-Charles emphasizes the ordinariness of the characters’ lives. She identifies joy, care, and the erotic as central to the other worlds the writers invite readers to imagine.
Netflix
Authors: Agina Añulika
Published: February 2025

The euphoria with which Netflix was greeted among Nigerian filmmakers when it extended its business interest to Nollywood soon gave way to suspicion and controversy by scholars and lawyers. While funding and distribution, two major problems faced by the industry, are improved by Netflix’s investment and global reach, local exhibition companies have their business models disrupted by the streamer. Additionally, local and transnational audiences get quicker access to box office hits due to Netflix’s licensing and acquisitions. This chapter takes up these controversies, using the lens of digital disruption to examine the nature and extent of Netflix’s impact on Nollywood. It uses interviews and social media posts of filmmakers over two years to assess the significance of the conflicting voices, arguing within a media industries framework that digital disruption introduces gains and losses for different actors, while generating new forms of storytelling and censorship typical of international capital.
South Africa's Female Only Filmmakers Project
Authors: Dovey Lindiwe
Published: February 2025

From 2000 to 2007, of the fifty-five South African films made, only six were directed by women, and only nine were written by women. In response, the South African National Film and Video Foundation initiated a project known as the Female Only Filmmakers project. This chapter focuses on the first iteration of the project, from 2013 to 2016, which was led by the film producer Bongiwe Selane, and it analyzes three of the films that were made as part of the project (and which are all examples of women moving from acting backgrounds into a rare opportunity to reveal their writing and directing talent): Panic Button (2014), The Groom’s Price (2017), and Mmino wa Modimo (2017). The chapter draws on interviews conducted with the filmmakers and is complemented by a documentary film the chapter’s author has made on the same topic titled From One Woman to Another: The Screen Worlds of Bongiwe Selane (2023).
Female Film Entrepreneurs in Ghana
Authors: Steedman Robin , Resario Rashida
Published: February 2025

Digital production and spectatorship have fundamentally disrupted the way Ghanaian filmmakers make movies and run their businesses. Digital distribution mechanisms have devastated parts of the industry principally because consumers no longer buy DVDs due to the accessibility of films on digital platforms such as YouTube, while at the same time distribution on online platforms has opened up new business models. This chapter examines women’s experiences of the digital transition through a comparison of two contemporary Ghanaian female filmmakers: Shirley Frimpong-Manso and Evelyn Asampana. Whether by developing a bespoke distribution platform or trying to build a business on YouTube, Frimpong-Manso and Asampana were ambitiously trying to seize digital opportunities, something that required a constellation of resources and competencies, so they could build the kinds of careers they wanted and produce the kinds of movies that resonated with their audiences.
Sex-Based Differences in Representation of Top Youth Athletes
Authors: James Jessica J. , Hunter Sandra K. , Bueckers Elizabeth P. , Joyner Michael J. , Senefeld Jonathon W.
Published: February 2025

Although emerging research demonstrates that male athletes outperform female athletes before puberty, the impact of these sex-related advantages on ordinal ranking of top performances remains unclear.

Objectives

Among overall top performances of youth track and swimming athletes, we aimed to determine: 1) the proportional number of male compared to female athletes represented and 2) at what age females are no longer represented.

Methods

Finishing times and sex of the top 10 and top 100 performances of youth runners and swimmers between 5-18 years were abstracted from online US-based databases for four running (100 m-800 m) and six freestyle swimming events (50 m-1500 m).

Results

Males represented a greater proportion of the top 10 performances starting at 7 years in running (P = 0.023) and 12 years in swimming (P = 0.023) (averaged across events). Males represented a greater proportion of the top 100 performances starting at 6 years in running (P < 0.001) and 7 years in swimming (P < 0.001) (averaged across events). Females were no longer represented within the top 10 performances starting at ~12 years in running and ~ 13 years in swimming and no longer represented within the top 100 starting at ~14 years in running and ~ 15 years in swimming.

Conclusions

In elite youth athletes, there was a greater proportion (representation) of males within the top 100 running and swimming performances beginning between ages 6 and 7, with females no longer represented between ages 14 and 15. Our findings suggest males are more likely to be represented “on the podium” in open sporting events (not categorized by sex) than females starting at age 6.
Design and additive manufacturing of a lightweight aerospace electric actuator
Authors: Lizarribar Carrillo Borja , Prieto Borja , Martínez-Iturralde Miguel , García Goikoetxea Javier , Montes Sergio , San José Ekain
Published: February 2025

Background The ambitious electrification targets set for the aeronautical sector are leading to a thorough research into improving the performance of different electromechanical components. In this regard, Additive Manufacturing is gaining strength due to the positive physical properties of the processed parts and the freedom in manufacturable geometries. Methods Thus, this article presents the design of an electric actuator for an aerospace active sidestick in which Additive Manufacturing is used with the aim of minimising the mass and power consumption of the device. The electromagnetic design of the actuator is detailed, considering 8 different permanent magnet machine topologies, and a mechanical design applying Topology Optimisation to reduce the overall mass of the component is carried out. Results Three prototypes involving the rotor, the stator and the casing are manufactured via Laser Powder Bed Fusion in stainless steel and Permendur (Fe49Co49V2) and the corresponding actuators are experimentally tested, showing a great agreement between tests and simulations and excellent repeatability in the electromagnetic behaviour of the prototypes. Conclusions The research results highlight the great potential of Additive Manufacturing to manufacture functional electrical machine components.
Wstęp
Authors: Bajda Justyna , Taranek-Wolańska Olga , Ucherek Dorota
Published: February 2025

Wstęp do numeru „Od deski do deski. Retoryka oprawy”.
Pół wieku okładek „Pamiętnika z powstania warszawskiego” Mirona Białoszewskiego
Authors: Poprawa Adam
Published: February 2025

W artykule omówiono okładki zaprojektowane do Pamiętnika z powstania warszawskiego wydawanego w latach 1970–2021. Autorzy tych projektów graficznych wybierali różne rozwiązania, od obrazów abstrakcyjnych do przedstawień mimetycznych, nawiązujących niejednokrotnie do konwencjonalnych tradycji. Zdarzały się propozycje zaskakujące, o dużych wartościach artystycznych.
Karakterne okładki. O projektach Przemka Dębowskiego
Authors: Ucherek Dorota
Published: February 2025

W artykule zanalizowano projekty okładek przygotowanych przez Przemka Dębowskiego dla wydawnictwa Karakter, a także zrekonstruowano proces ich kreacji graficznej oraz opisano sposoby przemawiania za ich pomocą do odbiorcy. Istotnym punktem odniesienia są wypowiedzi grafika, w tym zwłaszcza specyfika definiowania przezeń okładek oraz koncepcja czterech strategii komunikacyjnych, na których opiera on ich tworzenie. W ofercie oficyny znajdują się literatura piękna, literatura faktu, eseje oraz tytuły dotyczące designu, architektury i sztuki, materiał badawczy stanowią więc prace reprezentatywne dla poszczególnych gatunków. Jak pokazuje przeprowadzona analiza, Dębowski każde okładkowe zadanie traktuje indywidualnie, a poszukując rozwiązań najlepszych dla danego tytułu, swobodnie przechodzi od wzorców niemiecko-szwajcarskich do amerykańskich, czyli od surowości i minimalizmu do dynamiczności i żywiołowości. Nie stroni również od zabiegów budzących kontrowersje estetyczne, zawsze wprowadzanych rozmyślnie.
A cidade e reconfigurações dos vínculos sociais em tempos metamórficos
Authors: Oliveira Adriana Lima de , Castro Gisela Grangeiro da Silva
Published: February 2025

Este artigo aborda o espaço urbano contemporâneo sob dois aspectos: o primeiro é previsível e trata das questões da comunicação tecnológica inserida em uma economia imaterial financeira globalizada. O segundo é imprevisível e está relacionado à emergência de um contexto de crises – sanitária, ambiental, econômica e política. Nosso objetivo é contribuir para desvelar as camadas de sentido presentes nos fluxos comunicacionais que incorporam uma nova percepção do espaço urbano no cenário metamórfico, transfigurando as formas de ocupar o mundo e construir relações. Neste sentido, o tempo se impõe como elemento-chave na conquista de um modo de vida que leva em consideração a relação com o entorno e a comunidade. Importante destacar que o fato de estarmos conectados em rede não garante que estejamos nos comunicando, nem estreitando nossos vínculos sociais.
Iza e a “Fé nas maluca”:
Authors: De Souza Nayara Luiza , Pena Câmara Marco Túlio
Published: February 2025

Ao analisar o amor-próprio a partir de um compromisso que parte da ação de um fazer e um refazer-se consigo mesme/mesma/mesmo, bell hooks (2021) tensiona os imaginários que banalizam a construção identitária proposta por essa modalidade do amor. Destacando o poder da autodefinição como um Collins (2019) possibilitador para  o desenvolvimento do amor-próprio, sugerimos observar a representação do enfrentamento a normas patriarcais da branquitude realizado pela cantora brasileira mulher negra cisgênero Iza na produção do álbum AFRODHIT, lançado em 2023. Tomando como obra de análise o videoclipe/ curta-metragem “Fé nas maluca”,  propõe-se observar como a produção parte da desconstrução do mito da Vênus para exaltação da liberdade de mulheres que não se acorrentam pela catexia (hooks, 2021).
Palavras-chave: amor-próprio; mulheres negras; videoclipe
DESENVOLVIMENTO DE COMPETÊNCIAS NO ÂMBITO DO CURSO DE ADMINISTRAÇÃO:
Authors: Souza Lana Pereira Bárbara , Del Nero Flavio , Rodrigues Henrique Geraldo
Published: February 2025

Neste estudo, objetivou-se analisar em que medida estudantes e egressos de um curso de graduação em Administração desenvolveram as competências previstas no projeto pedagógico do curso e nas Diretrizes Curriculares Nacionais, e identificar as atividades de aprendizagem consideradas importantes à aquisição dessas competências. Trata-se de uma pesquisa de levantamento do tipo survey, com amostra não probabilística de 103 graduandos e egressos do curso de Administração de uma universidade pública. Os dados foram analisados pela estatística descritiva simples. Os resultados mostram que a maior parte dos participantes considera ter desenvolvido, em alguma medida, as competências previstas no curso. Também, se evidencia a relevância das atividades de aprendizagem vivenciadas no processo de desenvolvimento das competências. As contribuições geradas por este estudo são práticas, na medida em que a identificação da visão, de estudantes e de egressos, sobre em que medida as competências previstas para o curso foram desenvolvidas, possibilita, aos gestores acadêmicos, o exame das lacunas de competências, ou seja, as áreas de competências em que os estudantes percebem não haver um bom nível de aquisição de saberes. Tendo em vista que a aquisição de competências se dá pela vivência de atividades de aprendizagem, os gestores acadêmicos também têm a possibilidade de examinar quais atividades se evidenciam mais ou menos relevantes ao desenvolvimento de competências, pelos estudantes. Tais informações se mostram úteis tanto ao processo de revisão do projeto pedagógico de curso quanto à orientação à atuação de docentes, na condução de atividades de aprendizagem.
INTERAÇÃO DIALÓGICA EM ATIVIDADES DE EXTENSÃO:
Authors: Paulesky Juliani Douglas , Lucia de Pinho Grasiela
Published: February 2025

A extensão faz parte dos pilares da educação brasileira, juntamente com o ensino e a pesquisa. Ela é responsável por promover a troca de saberes entre as instituições de ensino e a comunidade, socializando o conhecimento produzido nas instituições e integrando-o aos saberes da comunidade e à realidade concreta, com o objetivo de transformar essa realidade. A interação dialógica alinha-se a essa perspectiva, defendendo que a comunidade tenha um papel central nas atividades extensionistas, participando e construindo todas as etapas, desde o planejamento e reconhecimento de demandas, até a execução e avaliação das ações. Há poucos estudos que abordam essa temática, principalmente na análise de como essas ações vêm sendo incorporadas na prática. Sendo assim, o objetivo deste estudo é analisar como ocorre a interação dialógica nas etapas que envolvem os projetos de extensão, tendo como local de estudo o Instituto Federal de Santa Catarina (IFSC). Trata-se de uma pesquisa aplicada, com abordagem qualitativa, de natureza exploratória e descritiva. A coleta de dados ocorreu por meio de documentos oficiais a respeito da extensão no IFSC, com a análise de 52 projetos aprovados junto à Pró-Reitoria de Extensão e Relações Externas (PROEX) nos editais n° 12/2022 e n° 16/2023. Esses dados foram analisados à luz do referencial teórico coletado para a fundamentação do estudo. Os resultados evidenciam a importância maior participação da comunidade durante as etapas que permeiam as ações extensionistas e indicam a necessidade de avanços nos debates da interação dialógica, promovendo maior impacto social no território.
ASPECTOS TRANSFORMADORES DA PAISAGEM NATURAL DO TABULEIRO DO EMBAUBAL - RIO XINGU (PA)
Authors: De Oliveira Livania Norberta , Trindade Roberto Ribeiro
Published: February 2025

O objetivo deste estudo foi observar as transformações exógenas e antrópicas da paisagem natural, ocorridas no Tabuleiro do Embaubal, reserva de desenvolvimento sustentável-RDS, localizada no baixo curso do rio Xingu entre 1993 a 2022. Utilizou-se de pesquisas bibliográficas e documental, além de trabalho de campo e analise temporal da paisagem através do geoprocessamento, pelo software Qgis 3.22.4. Foi feito o mapeamento da área, para identificar as vulnerabilidades e propor possíveis reparações, a médio e longo prazo, através de medidas mitigatórias dos impactos gerados. Evidenciou-se significativa alteração da paisagem, com aumento de solo exposto, bem como, o rebaixamento e espraiamento das barras arenosas provocado pela erosão, o avanço da pastagem para a criação de búfalos. Além de acentuado grau de desmatamento nas ilhas do Tabuleiro do Embaubal, modificação do nível e comportamento do corpo hídrico no geosistema. Verificou-se um conflito de interesse entre moradores e órgão gestor. Para tanto, faz-se necessário uma política de entendimento entre as partes, para buscar ações de conscientização e preservação da área de forma sustentável.
TOPOAPATIA, TOPOFILIA E TOPOFOBIA
Authors: Souza Júnior Carlos Roberto Bernardes de , Costa de Sousa Alexsandro
Published: February 2025

Lugares são espacialidades permeadas por emoções, vínculos e múltiplas formas de afeto que transcendem uma dimensão puramente extensiva do espaço. Em razão disso, faz-se possível estruturar geografias emocionais que interpretam as variadas relações corpo-sensoriais inerentes à lugaridade de ser-no-mundo. Nesse sentido, o ensaio almeja identificar como as emoções e os vínculos de lugar expressos na topofilia, na topofobia e na topoapatia se correlacionam a um espectro de afetos ambivalentes. Para tanto, parte-se da problematização teórico-metodológica fundamentada na Geografia Humanista e Cultural, especialmente no subcampo da Geografia das Emoções, articulada aos estudos das fenomenologias dos lugares e das emoções. Considera-se que as distintas manifestações dos vínculos de lugar pautados na afeição topofílica, no medo topofóbico e na supressão topoapática demonstram o dinamismo e as multiplicidades afetivas intrínsecas à experiência geográfica. As aberturas emocionais implicam em tramas de porosidades e polissemias do fazer-lugar, de forma a expressar teias de significados e sentidos que englobam dimensões intersubjetivas e intercorporificadas das lugaridades.
A EDUCAÇÃO PELO DINHEIRO
Authors: Sousa Neto Manoel Fernandes de
Published: February 2025

Editorial do Volume 21, Número 1.
Nociones de sociología de la desviación social para trabajo social
Authors: García-Aguña Sonia
Published: February 2025

El análisis del fenómeno de la desviación social y la delincuencia, desde diversas disciplinas y perspectivas teóricas, siempre ha estado en el núcleo del pensamiento social y teórico. En el presente artículo se profundizará en la cuestión mediante el estudio de la bibliografía sociológica al respecto. Para ello, se exponen los conceptos primordiales para ahondar más tarde en los prin-cipales análisis y sus autores/as más desta-cados/as, enmarcados dentro de los grandes para-digmas sociológicos; de la acción social, estructura-funcionalista, y del conflicto. Todo ello con el fin de presentar un marco teórico suficiente que permita comprender la cuestión y aportar perspectivas de relevancia capital para el Trabajo Social.
Why are girls becoming mothers? Exploring pregnancy determinants among high-risk women in Peru
Authors: Ticona Diana Manuela , Torreblanca-Rodriguez Sebastian M , Condori-Mamani Claudia E , Aquino-Salluca Alejandra , Aquino-Canchari Christian Renzo
Published: February 2025

Background/Aims

Adolescent pregnancy is a significant public health challenge that has biological, psychological and social implications. This study aimed to identify associations between adolescent pregnancy and socioeconomic, gender inequality and reproductive health indicators in Peru.

Methods

This retrospective ecological study explored the pregnancy rate among adolescents aged 10–14 years using data from the Peruvian online registry system of birth certificates (2017–2021). Indicator data were taken from various sources. Maps and simple linear regression models were used to analyse the association between indicators and the adolescent pregnancy rate.

Results

From 2017 to 2021, the pregnancy rate among adolescents was 0.28 per 100 live births, with jungle regions showing the highest rates. Completing secondary education (P<0.001) and contraceptive use (P=0.011) were associated with a decrease in pregnancy rate.

Conclusions

There was a significant association between early adolescent pregnancy and socioeconomic and reproductive health indicators.

Implications for practice

It is essential to improve access to secondary education and encourage contraceptive use in Peru, as both are linked to early adolescent pregnancy. Public health efforts should prioritise improving socioeconomic conditions and ensuring fair access to reproductive health services, especially in the most vulnerable areas.
Immune-mediated haemolytic anaemia: when blood is thinner than water
Authors: Kilpatrick Scott , Sorrell Stephanie
Published: February 2025

Immune-mediated haemolytic anaemia is a significant cause of morbidity and mortality in dogs and, although less common, can also occur in cats. Immune-mediated haemolytic anaemia can be classified as spontaneous (non-associative) when no underlying cause is identified, or disease-associated (associative) when triggered by infections, neoplasia, drugs, vaccines or inflammatory conditions. Diagnosis relies on identifying regenerative anaemia, spherocytosis and positive saline agglutination or Coomb's tests. Treatment involves immunosuppressive therapy, with corticosteroids as the first-line agent and additional immunosuppressants if there is a poor response. Blood transfusions may be required in severe cases, and thromboprophylaxis is recommended because of the risk of thromboembolism. The prognosis varies, with survival rates between 50% and 88% in dogs and approximately 77% in cats, though relapses are common. This article reviews the diagnosis, classification, treatment and prognosis of immune-mediated haemolytic anaemia in cats and dogs, incorporating recent research and consensus recommendations.
Small animal review
Authors: Gough Alex
Published: February 2025

Dog agility is an international sport that tests canine fitness and the abilities of the dog's handler to guide them through a preset obstacle course. However, as with all athletic activities, there is the potential for injury during training and competition. Three recent papers consider agility dog performance and factors that can contribute to injury.
Health professionals' practice experiences of infant mental health
Authors: Phillips Sophie , Davenport Caroline
Published: February 2025

Infant mental health (IMH) is a recognised but complex concept that can be threatened by difficulties in parent–infant attachment and trauma. The impact of poor infant mental health is long lasting; yet there is little existing literature regarding health professionals' experiences of infant mental health in practice. A literature review has examined the evidence base around infant mental health and professional practice experiences. Searches for primary qualitative research were achieved through relevant databases using appropriate search terminology related to the research question. Research shows there are various barriers to incorporating infant mental concepts into practice. These relate to time constraints and self-confidence. Furthermore, given the emotionally demanding nature of IMH, it increases the risk of compassion fatigue and burnout among health professionals. A deeper understanding of health professionals' experiences of IMH in practice can be used to implement recommendations to practice and research, to ensure infant mental health is incorporated into practice and staff members' emotional needs are supported. This ensures practice is trauma-informed and supports the prevention of further unnecessary suffering and widening of inequalities, which ultimately leads to improved quality of care.
Understanding parents' expectations of infant sleep: Part 1
Authors: Docherty Gillian , McMillan Laura
Published: February 2025

This article examines the importance of parental expectations of infant sleep. Adult and babies' sleep patterns are very different, but night-time waking and sleep disruption are inevitable for new parents. Parental expectations are influenced by historical and cultural factors, as well as advice from family members, health professionals and online sources. When expectations do not align with reality, parents may feel there is something wrong with their baby or doubt their parenting abilities. Consequently, unrealistic expectations can have a negative impact on parental mental health, infant care and parent–infant relationships. Despite limited evidence of their efficacy, parents may feel driven to attempt sleep training programmes due to misunderstanding of normal infant sleep patterns. Health visitors can help parents to understand and cope with infant sleep, and their role will be explored in the second part of this article.
The Impact of State COVID-19 Responses on People With Intellectual and Developmental Disabilities
Authors: Lineberry Sarah , Bogenschutz Matthew , Dinora Parthenia
Published: February 2025

Evidence suggests that the public health response to the COVID-19 pandemic exacerbated existing inequities, including for people with intellectual and developmental disabilities (IDD). People with IDD may have been at a higher risk for poor outcomes from COVID-19 than people without disabilities, but they were rarely prioritized in the public health response. Using multilevel modeling, we explored the impact of individual-level differences in combination with state-level policies on the likelihood of contracting COVID-19. Findings suggest that the ways people with IDD interact with their community, including where they live, impacted their risk during the COVID-19 pandemic, supporting calls to more actively consider people with IDD in future public health emergencies.
Evaluating the safety profile of the CoronaVac in adult and older adult populations: A phase IV prospective observational study in Brazil
Authors: Infante Vanessa , Cintra Monica Akissue de Camargo Teixeira , Fernandes Eder Gatti , Loch Ana Paula , Ragiotto Lucas , Braga Patrícia Emília , Salomão Maria da Graça , Lucchesi Maria Beatriz Bastos , de Oliveira Mayra Martho Moura , Gattás Vera Lúcia , da Silva Anderson Soares , Boas Paulo José Fortes Villas , Lopes Marta Heloisa , Moreira José , Boulos Fernanda Castro ,   CFV-01-IB study group
Published: February 2025

This Phase IV prospective observational study aimed to evaluate the frequency of solicited and unsolicited adverse reactions within seven days following the administration of each dose of CoronaVac (14-day interval) by age group (18–59 years and ≥60 years). Participants (n = 538; 487 adults and 51 older adults) were enrolled from three public health centers in São Paulo, Brazil from May 2021 to January 2022. The study involved a two-dose vaccination regimen administered 14 days apart. Solicited and unsolicited adverse reactions (ARs) were assessed within seven days after each dose, and medically attended adverse events following immunization (AEFI) were monitored for 42 days. Safety data were collected through participant diary cards, telephone follow-ups, and on-site visits. Among adults, the most frequently reported local AR after the first and second doses was pain (256 [52.6%] and 129 [29.5%], respectively), while the most common systemic AR was headache (158 [34.5%] and 51 [11.6%], respectively). Most local and systemic solicited ARs were of Grade 1 or 2 severity, with ARs being more prevalent in adults following the first dose. One serious adverse event related to the vaccine was reported in adults, with no fatalities. Nine adult participants experienced adverse events of special interest, including five cases of COVID-19. These findings support the overall safety profile of CoronaVac in adults and older adult individuals, with adverse events being generally mild and self-limited.
Multiomics in silico analysis identifies TM4SF4 as a cell surface target in hepatocellular carcinoma
Authors: Wong Kah Keng , Ab. Hamid Suzina Sheikh
Published: February 2025

The clinical application of cellular immunotherapy in hepatocellular carcinoma (HCC) is impeded by the lack of a cell surface target frequently expressed in HCC cells and with minimal presence in normal tissues to reduce on-target, off-tumor toxicity. To address this, an in silico multomics analysis was conducted to identify an optimal therapeutic target in HCC. A longlist of genes (n = 12,948) expressed in HCCs according to The Human Protein Atlas database were examined. Eight genes were shortlisted to identify one with the highest expression in HCCs, without being shed into circulation, and with restrictive expression profile in other normal human tissues. A total of eight genes were shortlisted and subsequently ranked according to the combination of their transcript and protein expression levels in HCC cases (n = 791) derived from four independent datasets. TM4SF4 was the top-ranked target with the highest expression in HCCs. TM4SF4 showed more favorable expression profile with significantly lower expression in normal human tissues but more highly expressed in HCC compared with seven other common HCC therapeutic targets. Furthermore, scRNA-seq and immunohistochemistry datasets showed that TM4SF4 was absent in immune cell populations but highly expressed in the bile duct canaliculi of hepatocytes, regions inaccessible to immune cells. In scRNA-seq dataset of HCCs, TM4SF4 expression was positively associated with mitochondrial components and oxidative phosphorylation Gene Ontologies in HCC cells (n = 15,787 cells), suggesting its potential roles in mitochondrial-mediated oncogenic effects in HCC. Taken together, TM4SF4 is proposed as a promising cell surface target in HCC due to its high expression in HCC cells with restricted expression profile in non-cancerous tissues, and association with HCC oncogenic pathways.