bluuebunny/crossref_metadata_2025 huggingface dataset:
Changes in motor behavior, neuropathology, and gut microbiota of a Batten disease mouse model following administration of acidified drinking water
Authors: Johnson Tyler B. , Langin Logan M. , Zhao Jing , Weimer Jill M. , Pearce David A. , Kovács Attila D.
Published: October 2019

CLN3 mutations cause the fatal neurodegenerative disorder, CLN3 Batten disease. The Cln3−/− mouse model displays characteristic features of the human disease including motor deficits. When mice received acidified drinking water (pH 2.5–2.9) instead of normal tap water (pH 8.4) for several generations, the motor skills of Cln3−/− mice normalized to control levels, indicating a disease-modifying effect of acidified water. Here we investigated if acidified water administered from postnatal day 21 has therapeutic benefits in Cln3−/− mice. Indeed, acidified water temporarily attenuated the motor deficits, had beneficial effects on behavioral parameters and prevented microglial activation in the brain of Cln3−/− mice. Interestingly, in control mice, acidified drinking water caused brain region-specific glial activation and significant changes in motor performance. Since the gut microbiota can influence neurological functions, we examined it in our disease model and found that the gut microbiota of Cln3−/− mice was markedly different from control mice, and acidified water differentially changed the gut microbiota composition in these mice. These results indicate that acidified water may provide therapeutic benefit to CLN3 Batten disease patients, and that the pH of drinking water is a major environmental factor that strongly influences the results of murine behavioral and pathological studies.
NMR-based metabolic profiling and comparison of Japanese persimmon cultivars
Authors: Ryu Shoraku , Muramatsu Tomonari , Furihata Kazuo , Wei Feifei , Koda Masanori , Miyakawa Takuya , Tanokura Masaru
Published: October 2019

Persimmons are a traditional, autumnal, and healthy fruit commonly consumed in Japan and East Asia based on the saying, “a persimmon a day keeps the doctor away.” The differences in metabolites among five major Japanese persimmon cultivars were investigated using a nuclear magnetic resonance (NMR)-based metabolomics approach. By using a broadband water suppression enhanced through T1 effects (WET) method for the sensitive detection of minor metabolites, better discrimination among cultivars and more informative details regarding their metabolic differences have been achieved compared to those achieved in conventional 1H NMR sequences. Among the nonastringent cultivars analyzed, the Taishu cultivar has the highest abundance of amino acids. The Matsumotowase-Fuyu cultivar contains ethyl-β-glycosides as characteristic components, which may relate to fruit softening. Citric acid concentration is higher in Maekawa Jiro than in other nonastringent cultivars. Among the two astringent cultivars analyzed, ethanol was significantly higher in Hiratanenashi than in Yotsumizo, which indicates different reactivity during deastringency treatments. The present study proposes an efficient and relatively quantitative metabolomics approach based on broadband WET NMR spectra.
Using artificial intelligence to read chest radiographs for tuberculosis detection: A multi-site evaluation of the diagnostic accuracy of three deep learning systems
Authors: Qin Zhi Zhen , Sander Melissa S. , Rai Bishwa , Titahong Collins N. , Sudrungrot Santat , Laah Sylvain N. , Adhikari Lal Mani , Carter E. Jane , Puri Lekha , Codlin Andrew J. , Creswell Jacob
Published: October 2019

Deep learning (DL) neural networks have only recently been employed to interpret chest radiography (CXR) to screen and triage people for pulmonary tuberculosis (TB). No published studies have compared multiple DL systems and populations. We conducted a retrospective evaluation of three DL systems (CAD4TB, Lunit INSIGHT, and qXR) for detecting TB-associated abnormalities in chest radiographs from outpatients in Nepal and Cameroon. All 1196 individuals received a Xpert MTB/RIF assay and a CXR read by two groups of radiologists and the DL systems. Xpert was used as the reference standard. The area under the curve of the three systems was similar: Lunit (0.94, 95% CI: 0.93–0.96), qXR (0.94, 95% CI: 0.92–0.97) and CAD4TB (0.92, 95% CI: 0.90–0.95). When matching the sensitivity of the radiologists, the specificities of the DL systems were significantly higher except for one. Using DL systems to read CXRs could reduce the number of Xpert MTB/RIF tests needed by 66% while maintaining sensitivity at 95% or better. Using a universal cutoff score resulted different performance in each site, highlighting the need to select scores based on the population screened. These DL systems should be considered by TB programs where human resources are constrained, and automated technology is available.
Topological pumping in Aharonov–Bohm rings
Authors: Haug Tobias , Dumke Rainer , Kwek Leong-Chuan , Amico Luigi
Published: October 2019

Topological Thouless pumping and Aharonov–Bohm effect are both fundamental effects enabled by the topological properties of the system. Here, we study both effects together: topological pumping of interacting particles through Aharonov–Bohm rings. This system can prepare highly entangled many-particle states, transport them via topological pumping and interfere with them, revealing a fractional flux quantum. The type of the generated state is revealed by non-trivial Aharonov–Bohm interference patterns that could be used for quantum sensing. The reflections induced by the interference result from transitions between topological bands. Specific bands allow transport with a band gap scaling as the square-root of the particle number. Our system paves a new way for a combined system of state preparation and topological protected transport.
PEDOT-based Thermoelectrics
Authors: Fan Zeng , Ouyang Jianyong
Published: October 2019

The poly(3,4-ethylenedioxythiophene) (PEDOT) family are regarded as the most popular thermoelectric (TE) polymers due to their advantages including easy doping level tunability, good air stability and high TE properties. Over the past few years, the TE properties of the PEDOT-based TE materials have been continuously improved. The highest room-temperature power factor (PF) and figure-of-merit (ZT) of the PEDOT films have reached over 700 µW m−1 K−2 and ∼0.75, respectively. This chapter introduces the state-of-the-art progress made in PEDOT-based TEs, including their chemical structure, microstructure, charge transport feature, doping level and structure–property relationship. These PEDOT-based TE polymers and composites hold great potential for applications in many fields, such as energy conversion and self-powered wearable electronics.
Flexible Organic-based Thermoelectric Devices
Authors: Zhang Kun , Zheng Yuanyuan , Chen Xinyi , Han Xue , Du Minzhi , Hu Xinzhi , Wang Liming , Wang Jilong , Lu Chunhong
Published: October 2019

It is intriguing to develop flexible thermoelectric generators for powering wearable electronics with low power consumptions, typically in the Internet of Things. Compared to inorganic counterparts, organic thermoelectric generators possess their own superior properties such as intrinsic flexibility and good solution processability etc. In this chapter, we discuss the fabrication, device performance and potential applications of flexible organic thin-film and textile-based thermoelectric generators.
Mechanistic insights on the non-innocent role of electron donors: reversible photocapture of CO2 by RuII-polypyridyl complexes
Authors: Queyriaux Nicolas , Swords Wesley B. , Agarwala Hemlata , Johnson Ben A. , Ott Sascha , Hammarström Leif
Published: October 2019

The ability of [RuII(tButpy)(dmbpy)(MeCN)]2+ (1-MeCN) to capture CO2, with the assistance of triethanolamine (TEOA), has been assessed under photocatalytically-relevant conditions.
Formation of uniform porous yolk–shell MnCo2O4 microrugby balls with enhanced electrochemical performance for lithium storage and the oxygen evolution reaction
Authors: Li Jia , Zhang Yongxing , Li Li , Wang Yanming , Zhang Lei , Zhang Baojie , Wang Fei , Li Bing , Yu Xin-Yao
Published: October 2019

Mixed transition metal oxides with favorable electrochemical properties are promising electrode materials in energy storage and conversion systems.
In search of tris(trimethylsilylcyclopentadienyl) thorium
Authors: Wedal Justin C. , Bekoe Samuel , Ziller Joseph W. , Furche Filipp , Evans William J.
Published: October 2019

Solution synthesis, characterization, and reactivity of a new Th(iii) complex Cp′3Th (Cp′ = C5H4SiMe3).
Insights into interface engineering in steam reforming reactions for hydrogen production
Authors: Chen Sai , Pei Chunlei , Gong Jinlong
Published: October 2019

This review provides deep insights into interface engineering and its central role in steam reforming reactions for H2 production.
Araucaria angustifolia(Bertol.) Kuntze extract as a source of phenolic compounds in TPS/PBAT active films
Authors: Silva Tamires Barlati Vieira da , Moreira Thaysa Fernandes Moya , de Oliveira Anielle , Bilck Ana Paula , Gonçalves Odinei Hess , Ferreira Isabel C. F. R. , Barros Lillian , Barreiro Maria-Filomena , Yamashita Fabio , Shirai Marianne Ayumi , Leimann Fernanda Vitória
Published: October 2019

There is growing interest in the development of biodegradable packaging materials containing natural antioxidant extracts.
Study of gastrointestinal tract viability and motilityviamodulation of serotonin in a zebrafish model by probiotics
Authors: Lu Youyou , Zhang Zhe , Liang Xi , Chen Yujie , Zhang Junxue , Yi Huaxi , Liu Tongjie , Yang Liuqing , Shi Hanping , Zhang Lanwei
Published: October 2019

Investigated gastrointestinal tract viability and effect of potential probiotics on intestinal motility and the synthesis of serotonin in a zebrafish model.
Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours
Authors: McDaid William J. , Greene Michelle K. , Johnston Michael C. , Pollheimer Ellen , Smyth Peter , McLaughlin Kirsty , Van Schaeybroeck Sandra , Straubinger Robert M. , Longley Daniel B. , Scott Christopher J.
Published: October 2019

The use of CTX as a targeting agent for camptothecin-loaded polymeric nanoparticles directed against KRAS mutant CTX-resistant cancer cells was investigated. CTX increased CPT internalisation into cancer cells resulting in elevated cancer cell death.
Scalable nanohybrids of graphitic carbon nitride and layered NiCo hydroxide for high supercapacitive performance
Authors: Patil Bebi , Park Changyong , Ahn Heejoon
Published: October 2019

A two dimensional CNLDH 0.1 nanohybrid supercapacitor electrode prepared by simple hydrothermal hybridization of g-C3N4 and NiCO LDH shows the maximum specific capacity of 183.43 mA h g−1 with remarkable electrochemical performance.
Study on methane hydrate formation in gas–water systems with a new compound promoter
Authors: Lv Xiaofang , Lu Dayong , Liu Yang , Zhou Shidong , Zuo Jiangwei , Jin Hao , Shi Bohui , Li Entian
Published: October 2019

The effects of a new promoter on the growth kinetics of methane hydrates were investigated using a visualized constant-pressure autoclave.
A greener approach towards the development of graphene–Ag loaded ZnO nanocomposites for acetone sensing applications
Authors: Nadargi Digambar Y. , Dateer Ramesh B. , Tamboli Mohaseen S. , Mulla Imtiaz S. , Suryavanshi Sharad S.
Published: October 2019

We report a facile, green synthesis of graphene/Ag/ZnO nanocomposites and their use as acetone sensors via a medicinal plant extraction assisted precipitation process.
Luminescent properties of a new cyan long afterglow phosphor CaSnO3:Lu3+
Authors: Zheng ChangRan , Liu QuanSheng
Published: October 2019

A new cyan long-lasting phosphor CaSnO3:Lu3+ was successfully synthesized at 1200 °C. The long-lasting phosphorescence (LLP) properties of the cyan phosphor were first discussed and the afterglow mechanism was expounded.
NaYF4:Yb,Tm@TiO2 core@shell structures for optimal photocatalytic degradation of ciprofloxacin in the aquatic environment
Authors: Ma Yongmei , Li Siyue
Published: October 2019

The study indicated the optimum operation conditions to effectively remove ciprofloxacin from aquatic environment by NaYF4:Yb,Tm@TiO2 structures.
Direct functionalization of white phosphorus with anionic dicarbenes and mesoionic carbenes: facile access to 1,2,3-triphosphol-2-ides
Authors: Rottschäfer Dennis , Blomeyer Sebastian , Neumann Beate , Stammler Hans-Georg , Ghadwal Rajendra S.
Published: October 2019

A series of unique C2P3-ring compounds [(ADCAr)P3] (4) are readily accessible in an almost quantitative yield by the direct functionalization of white phosphorus (P4) with appropriate anionic dicarbenes [Li(ADCAr)].
Anaerobic digestion of synthetic food waste-cardboard mixtures in a semi-continuous two-stage system
Authors: Asato Caitlin M. , Gonzalez-Estrella Jorge , Skillings Donald S. , Castaño Andrea Vargas , Stone James J. , Gilcrease Patrick C.
Published: October 2019

A two-stage anaerobic digestion system consisting of a continuously-stirred tank reactor and upflow anaerobic sludge blanket (CSTR-UASB) in series was evaluated for semi-continuous digestion of food waste and corrugated cardboard mixtures.
Perforated vesicles composed of amphiphilic diblock copolymer: new artificial biomembrane model of nuclear envelope
Authors: Yoshida Eri
Published: October 2019

Perforated vesicles as a new artificial model of perforated biomembrane for the nuclear envelope were prepared by photopolymerization-induced self-assembly.
A tannic acid-modified fluoride pre-treated Mg–Zn–Y–Nd alloy with antioxidant and platelet-repellent functionalities for vascular stent application
Authors: Wang Pei , Liu Jing , Luo Xujiang , Xiong Pan , Gao Shuang , Yan Jianglong , Li Yangyang , Cheng Yan , Xi Tingfei
Published: October 2019

This work explores a multifunctional surface coating with antioxidant and platelet-repellent and quick re-endothelialization properties for MgZnYNd alloy stent application.
Reusable gold nanorod/liquid crystalline elastomer (GNR/LCE) composite films with UV-triggered dynamic crosslinks capable of micropatterning and NIR actuation
Authors: Wu Zhongying , Liu Liang , Cheng Pin , Fang Jianglin , Xu Tianchi , Chen Dongzhong
Published: October 2019

A facilely prepared GNR/LCE composite film with UV-triggered reversible dynamic crosslinking capable of near infrared (NIR)-driven macroscopic deformations, precise micro-patterned localization and re-shapeability.
Thermally conductive, super flexible and flame-retardant BN-OH/PVA composite film reinforced by lignin nanoparticles
Authors: Wang Xiu , Ji Song-Lin , Wang Xin-Qi , Bian Hui-Yang , Lin Ling-Rui , Dai Hong-Qi , Xiao Huining
Published: October 2019

LNPs were utilized as functional fillers to enhance the thermal conductivity, flame-retardancy, and flexibility of BN-OH/PVA composite film.
How can a new Government signal its intent for science?
Authors: Tooze James
Published: October 2019

Against a backdrop of political uncertainty, the Campaign for Science and Engineering (CaSE) have been consistently building the argument for the Government's commitment to an increase in research and development funding—something all parties have targets towards. James Tooze from CaSE shares some thoughts on how the new Government can signal their support for science and research.
Evidence for an Association Between Hearing Impairment and Disrupted Sleep: Scoping Review
Authors: Clarke Nathan A. , Hoare Derek J. , Killan Edward C.
Published: October 2019

Purpose

Hearing impairment (HI) is the most common sensory impairment and may negatively impact sleep through reduced auditory input. Factors associated with HI such as anxiety regarding communication in daily life may also adversely impact an individual's sleep. Here, research on the relationship between HI and sleep disruption was catalogued using scoping review methodology.

Method

A systematic strategy was employed to search various electronic databases. This review is reported according to the Preferred Reporting Items for Systematic Review and Meta-Analyses Scoping Review Extension.

Results

Sixteen records met inclusion criteria. Studies have investigated sleep in HI as a primary aim in noise-exposed workers or large surveys in older participants. Experimental and quasi-experimental studies report alterations to sleep architecture of potential neuroplastic origins. Studies reporting sleep as a secondary aim generally report poorer sleep in HI participants.

Conclusions

This scoping review has catalogued evidence that altered or negatively impacted sleep may be associated with HI. Potential confounding factors, mechanisms, and considerations for future research are discussed.

Supplemental Material

https://doi.org/10.23641/asha.9968369
A 3D short-characteristics method for continuum and line scattering problems in the winds of hot stars
Authors: Hennicker L. , Puls J. , Kee N. D. , Sundqvist J. O.
Published: October 2019

Context. Knowledge about hot, massive stars is usually inferred from quantitative spectroscopy. To analyse non-spherical phenomena, the existing 1D codes must be extended to higher dimensions, and corresponding tools need to be developed.

Aims. We present a 3D radiative transfer code that is capable of calculating continuum and line scattering problems in the winds of hot stars. By considering spherically symmetric test models, we discuss potential error sources, and indicate advantages and disadvantages by comparing different solution methods. Further, we analyse the ultra-violet (UV) resonance line formation in the winds of rapidly rotating O stars.

Methods. We consider both a (simplified) continuum model including scattering and thermal sources, and a UV resonance line transition approximated by a two-level-atom. We applied the short-characteristics (SC) method, using linear or monotonic Bézier interpolations, for which monotonicity is of prime importance, to solve the equation of radiative transfer on a non-uniform Cartesian grid. To calculate scattering dominated problems, our solution method is supplemented by an accelerated Λ-iteration scheme using newly developed non-local operators.

Results. For the spherical test models, the mean relative error of the source function is on the 5 − 20% level, depending on the applied interpolation technique and the complexity of the considered model. All calculated line profiles are in excellent agreement with corresponding 1D solutions. Close to the stellar surface, the SC methods generally perform better than a 3D finite-volume-method; however, they display specific problems in searchlight-beam tests at larger distances from the star. The predicted line profiles from fast rotating stars show a distinct behaviour as a function of rotational speed and inclination. This behaviour is tightly coupled to the wind structure and the description of gravity darkening and stellar surface distortion.

Conclusions. Our SC methods are ready to be used for quantitative analyses of UV resonance line profiles. When calculating optically thick continua, both SC methods give reliable results, in contrast to the alternative finite-volume method.
Active coated nano rod antennas for enhanced and directive scattering phenomena
Authors: Arslanagić Samel , Jacobsen Rasmus E.
Published: October 2019

The scattering properties of a range of symmetric and asymmetric active coated nano rod antennas are investigated numerically. The active nano rods are composed of a silica dioxide nano-core coated with a silver nano-shell, and with a canonical gain model implemented into their nano-core regions. The asymmetric nano rods are obtained through suitable perforations of their nano-shell and/or nano-core regions. In all cases, active nano rods are found to exhibit super-resonant phenomena with significantly enhanced scattered fields for an incident plane wave having the magnetic field parallel to the rod axis. While the dipole-mode response in the symmetric cases is only weakly directive, the asymmetric cases stimulate an abundant emission of higher order modes furnishing rather enhanced and directive near-fields. As the length of the symmetric nano rods decreases, more gain is needed to achieve a super-resonant response, which also was found to be blue-shifted. For asymmetric cases, the gain was lowered, and the response got blue-shifted as the asymmetry increased. The proposed active nano rod antennas provide a new class of antennas with desirable wavelength tunability and polarization-dependent scattering properties; this makes them interesting candidates for many nano-photonic applications. Moreover, the proposed geometries bridge the important gap between the two often considered canonical geometries, namely, spherical and infinitely long cylindrical particles. The detailed knowledge of gain values and resonant wavelengths provided in here is crucial for a successful combination of such particles with realistic gain materials.
CMD-3 Overview
Authors: Logashenko Ivan B. , Ignatov F.V. , Akhmetshin R.R. , Amirkhanov A.N. , Anisenkov A.V. , Aulchenko V.M. , Banzarov V.S. , Bashtovoy N.S. , Berkaev D.E. , Bondar A.E. , Bragin A.V. , Eidelman S.I. , Epifanov D.A. , Epshteyn L.B. , Erofeev A.L. , Fedotovich G.V. , Gayazov S.E. , Grebenuk A.A. , Gribanov S.S. , Grigoriev D.N. , Ivanov V.L. , Karpov S.V. , Kazanin V.F. , Kirpotin A.N. , Korobov A.A. , Koop I.A. , Kozyrev A.N. , Kozyrev E.A. , Krokovny P.P. , Kuzmenko A.E. , Kuzmin A.S. , Lukin P.A. , Mikhailov K.Yu. , Okhapkin V.S. , Otboev A.V. , Pestov Yu.N. , Popov A.S. , Razuvaev G.P. , Ruban A.A. , Ryskulov N.M. , Ryzhenenkov A.E. , Senchenko A.I. , Shebalin V.E. , Shemyakin D.N. , Shwartz B.A. , Shwartz D.B. , Sibidanov A.L. , Shatunov P.Yu. , Shatunov Yu.M. , Solodov E.P. , Talyshev A.A. , Vorobiov A.I. , Yudin Yu.V. , Zemlyansky I.M.
Published: October 2019

The CMD-3 detector is installed at the VEPP-2000 e+e− collider at BINP (Novosibirsk, Russia). It is a general-purpose detector, equipped with a tracking system, two crystal (CSI and BGO) calorimeters, liquid Xe calorimeter, TOF and muon systems. The main goal of experiments at CMD-3 is a study of exclusive modes of e+e−→ hadrons at energies $ \sqrt s \le $ GeV. In particular, these results provide an important input for calculation of the hadronic contribution to the muon anomalous magnetic moment.

The first round of data taking was performed in 2011–2013, when about 60 1/pb were taken in the center-of-mass (c.m.) energy range from 0.32 to 2.0 GeV. Here we present a survey of results of data analysis.

Between 2013 and 2016 the collider and the detector were upgraded. The data taking resumed by the end of 2016. In the first run after the upgrade about 50 1/pb were collected at the energy range between 1.28 and 2.007 GeV. We discuss the upgrade and the first preliminary results from the new data.
Measurement of the e+e−→ π0γ cross section at SND
Authors: Kardapoltsev L. V. , Druzhinin V. P. , Kovrizhin D. P.
Published: October 2019

Recent SND results on the study of the process e+e−→ π0γ are presented. The study is based on data collected with the SND detector on the VEPP-2M and VEPP-2000 e+e− colliders with an integrated luminosity of 25 and 46 pb−1, respectively. The VEPP-2M data used in this analysis are recorded in the center-of-mass energy range 0.60-1.38 GeV, while the VEPP-2000 data in the range 1.05-2.00 GeV.
Preliminary results on CMD-3 measurement of e+e−→ π+π− cross section
Authors: Ignatov Fedor , Logashenko I.B. , Akhmetshin R.R. , Amirkhanov A.N. , Anisenkov A.V. , Aulchenko V.M. , Banzarov V.S. , Bashtovoy N.S. , Berkaev D.E. , Bondar A.E. , Bragin A.V. , Eidelman S.I. , Epifanov D.A. , Epshteyn L.B. , Erofeev A.L. , Fedotovich G.V. , Gayazov S.E. , Grebenuk A.A. , Gribanov S.S. , Grigoriev D.N. , Ivanov V.L. , Karpov S.V. , Kasaev A.S. , Kazanin V.F. , Korobov A.A. , Koop I.A. , Kozyrev A.N. , Kozyrev E.A. , Krokovny P.P. , Kuzmenko A.E. , Kuzmin A.S. , Lukin P.A. , Lysenko A.P. , Mikhailov K.Yu. , Okhapkin V.S. , Perevedentsev E.A. , Pestov Yu.N. , Popov A.S. , Razuvaev G.P. , Rogovsky Yu.A. , Ruban A.A. , Ryskulov N.M. , Ryzhenenkov A.E. , Shebalin V.E. , Shemyakin D.N. , Shwartz B.A. , Shwartz D.B. , Sibidanov A.L. , Shatunov Yu.M. , Solodov E.P. , Talyshev A.A. , Vorobiov A.I. , Yudin Yu.V.
Published: October 2019

The CMD-3 detector has been successfully collecting data at the electron-positron collider VEPP-2000 since December 2010. The first scan below 1 GeV for a π+π− measurement was performed in 2013. The collected data sample corresponds to about 18 pb−1 of integrated luminosity in this energy range. Analysis of the e+e−→ π+π− cross section is in progress. Status of this measurement are presented.
Initiation à la conception d’antennes Yagi-Uda pour des lycéens
Authors: Avrillon S.
Published: October 2019

Dans le cadre des actions de sensibilisation vers l’enseignement secondaire du projet ANR FINMINA [2], une initiation à la conception d’antennes est proposée aux lycées de l’Académie de Rennes. Dans ce cadre, depuis 2016, plusieurs groupes d’élèves sont venus dans les salles de travaux pratiques de la plateforme électronique de l’Université de Rennes 1 pendant deux demi-journées afin de dimensionner, simuler, réaliser et mesurer une antenne Yagi pour des applications WiFi.
Micro OLED rapide sur électrodes coplanaires pour un fonctionnement en régime d'excitation impulsionnelle nanoseconde
Authors: Chime A. C. , Solard J. , Chakaroun M. , Nkwawo H. , Fischer A. P. A.
Published: October 2019

Dans ce travail, nous nous intéressons à la conception, à la réalisation de micro-OLEDs ultra rapides et à leur caractérisation en régime d’excitation électrique impulsionnelle nanoseconde. Les réponses ultra-rapides de ces μ-OLED sont obtenues par des électrodes spécifiques empruntées aux techniques micro-ondes. Cette combinaison de l’électronique organique et des techniques micro-ondes permet d’atteindre des valeurs record en termes de durée d'impulsion d’excitation ultra courte (5 ns) et de densité de courant ultra-intense (4,7 kA/cm2). Ces résultats ouvrent des perspectives vers la réalisation de la première diode laser organique.
Les cartes d’extension PCBmod : conception et applications pédagogiques VHDL et micro-assemblage
Authors: Guédon-Gracia A. , Debéda H. , Tomas J.
Published: October 2019

Nous avons développé et fabriqué des cartes d’extension compatibles avec les connecteurs Pmod des cartes de développement FPGA de la société Digilent. Ces cartes sont appelées PCBmod et sont au nombre de quatre actuellement. Elles intègrent respectivement des convertisseurs, des capteurs de température et de pression ainsi qu’un circuit date-calendrier ; tous ces composants possèdent un protocole de communication SPI. Ces PCBmod sont utilisés au niveau Master en tant qu’exemple d’application lors du stage micro-assemblage, et en tant que périphériques divers et variés lors de TP et projet VHDL.
Carte électronique générique à base de compensateurs avance-retard pour les travaux pratiques d’automatique continue
Authors: Omran H. , Madec M. , Bayle B. , Schuh V.
Published: October 2019

Dans le cadre des travaux pratiques d’automatique en première année à Télécom Physique Strasbourg, nous avons conçu une carte électronique unique permettant la réalisation d’une large gamme de correcteurs pour l’asservissement continu sur des systèmes divers : moteur, système de chauffage, lévitation magnétique. La carte est constituée de trois circuits d’entrée permettant l’implémentation d’un filtre du premier ordre, de quatre modules correcteurs constitués chacun d’un compensateur à avance-retard de phase, d’un additionneur et d’un soustracteur, ainsi que de trois sorties. Cette maquette permet aux étudiants de réaliser facilement différents asservissements en interconnectant les blocs entre eux et en ajustant les valeurs de composants passifs (résistances et condensateurs) de sorte à obtenir les fonctions de transfert calculées en préparation. L’utilisation de la maquette est illustrée dans cet article sur l’un des exercices de TP : l’asservissement en position d’une bille magnétique.
Coupleurs microondes en guide rectangulaire en bande Ku par impression 3D plastique
Authors: Laplanche E. , Tantot O. , Delhote N. , Périgaud A. , Verdeyme S. , Barelaud B. , Gramond René-Philipe
Published: October 2019

Dans ce papier est présentée la conception de coupleurs directifs microondes basés sur des guides d’ondes volumiques facilement imprimables en plastique par technologie FDM ou Polyjet©. La conception d’un coupleur en guides d’ondes croisés est abordée à la manière d’un projet sub-divisible en plusieurs phases, de la bibliographie à la mesure du dispositif une fois celui-ci imprimé. L’ensemble de ces phases étant relativement interdépendantes, il est possible de se concentrer uniquement sur l’une d’elles dans le cadre d’une séance de travaux pratiques, ou d’en sélectionner plusieurs dans le cadre d’un projet par exemple.

Dans une seconde partie, deux topologies de coupleurs hybrides se prêtant également bien à ce type de projets sont présentées, à savoir des coupleurs Short-Slot et Ladder-Type.
De la conception à la fabrication de circuits intégrés en technologie CMOS
Authors: Tap H. , Tan R.P. , Bernal O. , Calmon P-F. , Rouabhi C. , Capello C. , Bourdeu d'Aguerre P. , Gessinn F. , Respaud M.
Published: October 2019

L’objectif de ce projet pédagogique est de proposer à des étudiants de niveau Master ou Ingénieur en Electronique un module complet leur permettant de se familiariser avec la conception et la fabrication de circuits intégrés analogiques répondant spécifiquement à un cahier des charges. L’autonomie et la prise d’initiatives sont favorisées par le mode d’Apprentissage Par Projet (APP). Le projet, d’une durée totale de 9 journées permettra à une équipe constituée de 2 binômes d’étudiants de réaliser un circuit CMOS personnalisé selon un cahier des charges, à partir de la modélisation de la filière technologique NMOS et PMOS accessibles à la centrale technologique de l’Atelier Interuniversitaire de Micro-nano Electronique (AIME) de Toulouse. Ce projet vise à placer les étudiants dans un contexte proche d’une situation en milieu professionnel, où ils doivent concevoir, réaliser et tester une solution répondant à un cahier des charges. A l’issue des tests expérimentaux, les étudiants présenteront leurs résultats au travers d’un rapport écrit et d’une présentation orale. Ils devront analyser les écarts aux cahiers des charges et les écarts entre calculs théoriques/simulation et mesures ; puis proposer les voies et alternatives qui permettraient d’améliorer leurs solutions.
Actions de vulgarisation du guichet national de formation continue du GIP-CNFM
Authors: Pradarelli B. , Nouet P. , Benoit P. , Bonnaud O.
Published: October 2019

Cet article présente les actions de dissémination et de vulgarisation mises en oeuvre pour promouvoir l’offre de formation continue en Microélectronique et en Nanotechnologies du réseau GIP-CNFM. Il rappelle la structuration et organisation du guichet d’entrée national et dresse le bilan 2014-2018 des formations continues réalisées dans le cadre du projet ANR IDEFI-FINMINA. Il conclut en adressant l’actualité et les nouvelles actions identifiées pour accroître la visibilité du GIP-CNFM dans le milieu de la formation professionnelle continue.
An Effective Approach for Land Use Management in the Palestinian territories
Authors: Hani Azzedine
Published: October 2019

The current understanding of the causes of land-use change is dominated by simplifications, which in turn, underline many environment-development policies that led to unsustainable situation in Gaza City. Therefore, this research aims at establishing an integrated land-use management framework for Gaza city based on cause-effect relationship within sustainability context. It also aims at establishing a prediction model for the relationship between the most influential socio-economic, environmental and institutional indicators that had shaped the current land-use status of the city for the period 1967-2003. The methodology presented in this research work, offers opportunities to simulate the future demand of the different land-uses based upon actual land-use conditions and other determinant factors. The determinant variables of land-use changes have been identified and prioritized using statistical analysis and Artificial Neural Network (ANN). The results were compared with other statistical techniques and expert opinions. ANN prediction model helped in drawing scenarios for future development. Combinations of socio-economic, environmental and institutional variables in addition to the actual land use for the last four years are used as a basis of land-use change explanations and modeling. These pathways indicate that land-use policies and projections for the future must not only capture the population indicators as the only drivers for land-use change but also account for the specific human resource development indicators and urban-environmental conditions. This recognition requires moving beyond some of the simplifications that persist in much of the current understanding of the causes of land-use change and its driving forces. The analysis of the local expert’s opinions provide evidence support the conclusion that the simple answers found in population growth, poverty and infrastructure rarely provide an adequate explanations of land-use changes. Rather, social responses follow from changing economic conditions, mediated by institutional factors are the real causes for land-use changes in Gaza.
Uses of Augmented reality for urban utilities management
Authors: KADDIOUI Ahmed , Shahrour Isam , El Oirrak Ahmed
Published: October 2019

Augmented reality (AR) is based on supplementing the view of the physical world with a computer-generated content such as text, images videos, sound, 3D objects etc. The proliferation of smart mobile devices and their high computational capabilities combined with the possibility of GIS 3D visualization and interaction have enabled new kinds of mobile applications. AR is considered as an efficient technology for the underground utilities management. Damages to underground utility lines are considered as one of the major urban problems because incidents caused by unsafe digging practices can compromise community safety and disconnect people from vital services. A prospective study was conducted to identify examples and characteristics of each type of augmented reality. This paper summarizes researches about the types of AR and discuss how this technology could help in underground utilities repairing and maintenance. We present a new mobile location based augmented reality system using smart device sensors and the Real Time Kinematic (RTK) satellite navigation technology of ORPHEON network for the location accuracy. This system enables GIS data visualization to help field workers in outdoor maintenance of underground infrastructures.
An integrated approach for jointed rock slope stability analysis using stochastic discrete fractures: A case study in mountains area
Authors: Chen Weizhong , Wang Luyu , Tan Xuyan , Lei Jiang
Published: October 2019

Stochastic discrete fractures are ubiquitous in practicing engineering and contribute much to the stability for geological mediums. In contrast to the traditional treatments based on continuum mechanics, we propose an integrated approach using discrete fractures based on an improved hybrid finite element method (FEM). A typical jointed rock slop is selected as a case study and then was simulated in the light of geological conditions for the study site. The basic equations of fracture domains are derived to generate stochastic discrete fractures which render a fundamental to the model. To implement this procedure through computer program, discrete fractures generating algorithm was developed. In the aspect of discretization, we presented a meshing scheme and proposed an algorithm to create fracture elements. To evaluate rock slope stability in a quantitative way, safety factor is calculated by strength reduction method. Numerical simulations were carried out showing the mechanical behaviors of jointed rock slope under different boundary conditions.
Seismic analysis on cross joint of utility tunnel
Authors: Wang Chang-xiang , Wang Meijing , Liang Jianwen
Published: October 2019

The finite element software ABAQUS is used to establish the seismic time-history analysis model of the utility tunnel joints. The viscoelastic boundary is employed to input the seismic wave through the equivalent nodal force. Considering the nonlinearity of the soil and concrete materials, the internal force of the cross-shaped utility tunnel is calculated, and the influence effect and influence range of the cross joints of the utility tunnel are also studied. Studies have shown that the internal forces near the cross joints increase significantly. The research has certain reference value for the seismic design of the cross joints in utility tunnel.
Synthesis of numerical methods for the design of segmental tunnel lining
Authors: Trad Rim , Mroueh Hussein , Bian Hanbing , Cormery Fabrice
Published: October 2019

This paper presents a numerical study that aims to compare the behavior of the segmental tunnel lining using the direct, indirect and experimental methods. This model is based on a practical case applied in university of Tongji: a project of water conveyance tunnel. A reduction in the bending moment and increasing of the displacement in the tunnel lining is showed in numerical results, when taking into account the effect of the joints. It has been shown that the number of joints in the tunnel-lining structure highly affects the results in terms internal forces and displacements. Furthermore, the internal forces obtained by the continuous method are high compared to the other methods when the effects on segmental joints on tunnel lining behaviour are usually considered. Additionally, the bending moment of the direct method with behaviour of rotation spring linear and experimental method is comparable.
Analyse médico-légale dans les arts premiers et intégrité scientifique
Authors: Jacqueline Sophie , Charlier Philippe
Published: October 2019

La communauté scientifique, dans son ensemble, se préoccupe de plus en plus des questions de déontologie et d’intégrité de la recherche. Au cours de notre travail de thèse portant sur les intérêts et les limites de l’étude des œuvres d’art premier, nous avons été amenés à réfléchir sur la place de l’intégrité scientifique dans nos recherches. Nous avons observé que celle-ci ainsi que ses manquements pouvaient impliquer différents acteurs : la communauté scientifique, mais également les communautés autochtones desquelles provenaient les œuvres que nous étudions, et la communauté du marché de l’art. Nous avons donc voulu comprendre comment un manquement à l’intégrité de la recherche pouvait être préjudiciable pour la science, mais également en affecter les différents acteurs. Pour cela, nous nous sommes intéressés à la circulation des œuvres d’art premier, et plus particulièrement à leur restitution, cette dernière faisant intervenir les différents acteurs que nous avons évoqués. Nous présentons ici une courte analyse de nos observations et quelques visées prospectives.
Intelligence clinique et intelligence artificielle
Authors: Matuchansky Claude
Published: October 2019

L’intelligence artificielle (IA) actuelle en médecine peut se prévaloir de grandes performances, particulièrement en analyse d’images à visées diagnostique et pronostique, mais, en pratique clinique quotidienne, les résultats de l’IA fondés sur des données probantes restent peu nombreux. Dans cet article, sont analysés les caractéristiques de l’intelligence clinique en pratique médicale, puis les succès et promesses de l’IA, de même que les limites, réserves et critiques apportées à l’introduction de l’IA en clinique de première ligne. Est soulignée l’importance de certains aspects éthiques et de régulation, notamment une « garantie humaine » à l’IA, telle que celle suggérée par le Comité consultatif national d’éthique pour les sciences de la vie et de la santé (CCNE). L’intelligence clinique pourrait être cette garantie humaine de l’IA en médecine, leur complémentarité pouvant conduire à une qualité de décisions largement supérieure à celle fournie séparément par chacune d’elles.
Decentralized decomposition algorithms for peer-to-peer linear optimization
Authors: Aydin M. Asli , Taşkin Z. Caner
Published: October 2019

We propose Decentralized Benders Decomposition and Decentralized Dantzig–Wolfe Decomposition algorithms for large-scale block angular linear programming problems. Our methods allow multiple peer decision makers to cooperate with the aim of solving the problem without the need of a central coordination mechanism. Instead we achieve cooperation by partial information sharing across a strongly connected communication network. Our main goal is to design decentralized solution approaches for decision makers who are unwilling to disclose their local data, but want to solve the global problem collaboratively for mutual benefit. We prove that our proposed methods reach global optimality in a finite number of iterations. We confirm our theoretical results with computational experiments.
Dermoid sinus in the perirectal fossa of a Siamese cat with involvement of the vaginal wall
Authors: Habenbacher Bettina , Adrian Anna M. , Nelissen Pieter
Published: October 2019

A 2.5-year-old spayed female Siamese cat was presented with a recurrent exudative wound in the right perirectal fossa. Clinical examination at presentation revealed a 1 cm long open wound with purulent discharge in the right perirectal fossa but was otherwise unremarkable. A computed tomography contrast-enhanced study showed a tracking sinus which could be traced from the right dorsolateral perianal region right up to the level of the vagina. Surgical exploration was performed from the perirectal region. The intermuscular sinus tract, which formed a cystic structure and connected to the vaginal wall, was en bloc excised. Histopathological examination confirmed the diagnosis of a dermoid sinus in the perirectal fossa with vaginal infiltration. To the authors’ knowledge, this is the first case report in the veterinary literature of the successful surgical management of a dermoid sinus in the perianal region connected to the vaginal wall in a cat.
Pferderücken statt Klassenzimmer – Hippotherapie und heilpädagogisches Voltigieren
Authors: Raß Lisa
Published: October 2019

Was passiert, wenn eine Schülergruppe mit körperlichem und sozial-emotionalem Förderbedarf einen Reiterhof besucht? Die Kinder lernen, und zwar eine ganze Menge – nicht nur auf dem Pferd, sondern auch bei den kleinen Arbeiten und Erlebnissen drumherum. Während diejenigen mit dem größten Förderbedarf zur physiotherapeutischen Einzelbetreuung gehen, nehmen die anderen am heilpädagogischen Voltigieren teil. Der Spaß an der Sache wirkt auf vielen Ebenen wie ein Lernverstärker.
Ja? Nein? Vielleicht später … – Unangenehme Entscheidungen treffen
Authors: Freitag-Herse Barbara
Published: October 2019

Ein Konfliktgespräch steht an. Und nun? Erst mal einen Tee zu trinken und die Pflanzen zu gießen, ist keine gute Idee. Als Führungskraft begegnen Sie Ihrer Angst vor unliebsamen Entscheidungen am besten mit Mut und Entschlossenheit – das gelingt mit nur sechs Schritten.
Patienten mit Tic-Störungen: weit bekannt, doch unterversorgt
Authors: Schnell Jaana M. L. , Weidinger Elif , Musil Richard
Published: October 2019

Das Bewusstsein der Öffentlichkeit für Tic-Störungen und insbesondere für das Tourette-Syndrom ist durch zahlreiche Medienbeiträge in den letzten Jahren gestiegen. Immer wieder wird in TV- oder Printmedien jedoch lediglich von schweren Fällen des Tourette-Syndroms berichtet, die nicht dem durchschnittlichen Krankheitsverlauf entsprechen. Eine umfangreiche Aufklärung über Symptome, Verlauf, Ursachen und Behandlungsmöglichkeiten ist daher wünschenswert 1.
Genauigkeitsevaluierung der Volumennavigation von Sonografie und Computertomografie anhand eines Phantoms
Authors: Moritz Anne-Kristin , Winter Karsten , Köhler Claudia , Alef Michaele , Kiefer Ingmar
Published: October 2019

Gegenstand und Ziel Gewebeveränderungen lassen sich bei Überlagerungen durch Gas im Magen-Darm-Trakt oder die Rippenbegrenzung sonografisch nicht darstellen, sind dagegen in der CT gut darstellbar. Die Verknüpfung von Sonografie und CT kann eine verbesserte Aussagekraft im Vergleich zur alleinigen Sonografie schaffen und als Volumennavigation im registrierten Datensatz als Hilfsmittel eingesetzt werden. Zur Diagnosesicherung eines verdächtigen Herdes ist eine Gewebeprobe nötig, die unter sonografischer Kontrolle entnommen werden kann. Auch hier lässt sich die ortskorrekte Fusion CT/Sonografie nutzen, um durch Ausschaltung von Überlagerungen im sonografischen Bild – eine Limitation der Sonografie – Herde besser darzustellen. Ob die Fusion CT/Sonografie exakt ist und welches Registrierungsprotokoll die höchste Genauigkeit aufweist, wurde in der vorliegenden Studie untersucht.

Material und Methoden Von 16 hergestellten Modellen (10 Modelle mit Erbsen [Low-Contrast-Modell], 6 Modelle mit Holzkugeln [High-Contrast-Modell] als Rundstrukturen) wurden CT-Datensätze erstellt, anhand von 3 Protokollen der Volumennavigation fusioniert und sonografisch untersucht. Die Abweichung der Probekörper wurde gemessen.

Ergebnisse Es erfolgten 1026 Messungen der Modelle mit Erbsen und 648 Messungen der Modelle mit Holzkugeln. Bei 9,9 % (102/1026) bzw. 9,9 % (64/648) der Modelle konnte eine 100 %ige Registrierungsgenauigkeit bestimmt werden. Bei 85,4 % (876/1026) bzw. 94,1 % (610/648) lag die Abweichung der Strukturen < 5 mm und bei 98,1 % (1006/1026) bzw. 99,4 % (644/648) < 10 mm. Das Registrierungsprotokoll, bei dem alle gesetzten Referenzpunkte für die Erstellung der ortskorrekten Fusion zwischen Ultraschall- und CT-Datensatz genutzt wurden, zeigte die genauesten Fusionsergebnisse.

Schlussfolgerung Die Registrierungsprotokolle der volumennavigierten Sonografie weisen eine für Biopsien ausreichend hohe Genauigkeit bei der Fusion identischer Lokalisationen auf und stellen die Grundlage für eine verbesserte volumennavigierte Biopsie dar.
Prävalenz kongenitaler sensorineuraler Taubheit bei reinrassigen Katzen
Authors: Betz Daniela Simon
Published: October 2019

Mari L, Freeman J, Van Dijk J et al. Prevalence of congenital sensorineural deafness in a population of client-owned purebred kittens in the United Kingdom. J Vet Intern Med 2019; 33: 1707–1713.

Kongenitale sensorineurale Taubheit (KST) ist eine bekannte Entität bei weißen, blauäugigen Katzen, die auf dem autosomal dominanten W-Gen beruht. Der Mehrzahl der Publikationen zu KST bei Katzen liegen Untersuchungen in Forschungskolonien zugrunde. Das Ziel der vorliegenden Studie war daher, die Prävalenz uni- und bilateraler KST durch eine Evaluation mittels Ableitung akustisch evozierter Potenziale (AAEP) bei einer Population reinrassiger Katzenwelpen in Privatbesitz zu ermitteln.