bluuebunny/crossref_metadata_2025 huggingface dataset:
The First Look in Autism Spectrum Disorder (ASD) Geographical Distribution in National Reference Hospital, South Sumatera Region, Indonesia
Authors: Maritska Ziske , Prananjaya Bintang Arroyantri , Parisa Nita
Published: April 2020

Background. Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized with disorders in cognitive, behaviour, and social interaction. It is estimated to affect 1:160 children worlwide. Despite its increasing trend, the exact cause of it is yet to be known.

Objective. This study wished to identify the geographical distribution of ASD cases in Dr. Mohammad Hoesin Hospital as one of the national reference hospitals in Indonesia for South Sumatera region.

Methods. Medical records of the patients who are diagnosed with ASD during 2014-2018 was observed in order to identify the patientsâ€™ residential area.

Results. There were 107 patients who were clinically diagnosed of having ASD during 2014-2018 in Dr Mohammad Hoesin Hospital, Palembang.  Based on its residential area, ASD cases were mostly found in Palembang as the capital city of South Sumatera Province.

Conclusion. ASD is found in small and big cities across the South Sumatera province, implying its common occurrence.  The varied prevalence could be signifying the role of different related risk factors identified in the area.
Review on Stereo Vision Based Depth Estimation
Authors: Degadwala Sheshang , Vyas Dhairya , Mahajan Arpana
Published: April 2020

Stereo vision is a challenging problem and it is a wide research topic in computer vision. It has got a lot of attraction because it is a cost efficient way in place of using costly sensors. Stereo vision has found a great importance in many fields and applications in today’s world. Some of the applications include robotics, 3-D scanning, 3-D reconstruction, driver assistance systems, forensics, 3-D tracking etc. The fundamental test of sound system vision is to create exact difference map. Sound system vision calculations for the most part perform four stages: first, coordinating cost calculation; second, cost collection; third, dissimilarity calculation or enhancement; and fourth, divergence refinement. Sound system coordinating issues are likewise examined. An enormous number of calculations have been produced for sound system vision. But characterization of their performance has achieved less attraction. This paper gives a brief overview of the existing stereo vision algorithms. After evaluating the papers we can say that focus has been on cost aggregation and multi-step refinement process. Segment-based methods have also attracted attention due to their good performance. Also, using improved filter for cost aggregation in stereo matching achieves better results.
Study of Wear Rate On Graphene and S-Glass Reinforced Al-6061 Metal Matrix Composites
Authors: R. Verma , Kumar P. Vijaya , K. A. Meghashree , P. Puneeth
Published: April 2020

This research work investigated the effect of the graphene and S-glass fiber on the wear rate of the Al6061 / S-Glass & Graphene particulate MMCs. Metal Matrix Composites (MMC’s) consist of either pure metal or an alloy as the matrix material, while the reinforcement generally a ceramic material. Aluminium composites are considered as one of the advanced engineering materials which have attracted more and more benefits. Now a days these materials are widely used in space shuttle, commercial airlines, electronic substrates, bicycles, automobiles, etc., Among the MMC’s aluminium composites are predominant in use due to their low weight and high strength. The key features of MMC’s are specific strength and stiffness, excellent wear resistance, high electrical and thermal conductivity. Hence, it is proposed to form a new class of composite. The Al 6061(Aluminium alloy 6061) reinforced with graphene and S-glass fiber to form MMCs were investigated. The stir casting technique of liquid metallurgy was used for the fabrication of the composite material. The composite was produced for different percentages of graphene and S-Glass fiber(varying Graphene with constant S-Glass fiber and varying S-Glass fiber with constant Graphene percentage). The specimens were prepared as per ASTM standard size by turning and facing operations to conduct corrosion tests and they were tested using pin on disk apparatus with varying load and speed in different comobinations. Through the results, it is concluded that wear rate increased with the increase in speed and load for every combination of the composite. However with Graphene being the main reinforcement with addition of Graphene wear rate has reduced marginally.
KEMAMPUAN BAHASA ARAB DALAM PANDANGAN PERILAKU KEAGAMAAN DAN KEMAMPUAN MENULIS ARAB (KHAT)
Authors: Mustofa Dedi
Published: April 2020

Writing is one of the very penting.melalui language skills to write someonewill be able to more easily convey the message in writing and can undersandand remember the message from a script or text. However, writing the Arabiclanguage itself is inseparable from the ability to maser handwriting. Without anundersanding of khat good, allows a person to experience an error in writing theArabic alphabet even in undersanding the message of an Arabic text. The purposeof this sudy was to determine how much inﬂuence the ability of the Masery ofArabic handwriting and religious behavior of a person.
DESAIN PENGEMBANGAN KURIKULUM PEMBELAJARAN BAHASA ARAB DI MALAYSIA
Authors: Khoiriyah Hidayatul
Published: April 2020

The purpose of this sudy is to describe the education sysem and fnd out the Arabiclearning curriculum in Malaysia in terms of objectives, methods, and evaluation.This research is a research in the form of library research that is qualitative innature and takes the object of curriculum research documents in Arabic learningin Malaysia. The data used as a source of writing are archives from the Minisryof Education of Malaysia which are accessed via the internet, and several articlesrelating to the sudy. The results of the sudy indicate that the Arabic languagelearning curriculum in Malaysia aims to have four language skills, but has not yetreached the sage of interacting and communicating, both verbally and in writing.The method used in Malaysia is the inquiry method, cooperative, etc. As for inMalaysia, the evaluation was carried out in summative and formative assessments.
Kedudukan Badan Pemeriksaan Keuangan dalam Sistem Ketatanegaraan Republik Indonesia
Authors: Primananda Alfath Tahegga
Published: April 2020

Supreme Audit Agency is derived from the Raad van Rekenkamer in the days of theDutch East Indies . The results of the audit or examination conducted an auditing firm to bedeposited to the Parliament and the Council for further action . Supervisory powers to theAudit Board is not surprising that no mention coincide with supervisory functions in theHouse . If it is interpreted as the Audit Board is also included as an auxiliary to the functionsof the House of Representatives in the field of oversight of government performance. so this iswill analysis about Position the Board of Audit in the constitutional system of the Republic ofIndonesia.Keywords: authority, state organs, and constitution.
IMPULSE Moment-by-Moment Test: An Implicit Measure of Affective Responses to Audiovisual Televised or Digital Advertisements
Authors: Calvert Gemma Anne , Trufil Geraldine , Pathak Abhishek , Fulcher Eamon Philip
Published: April 2020

IMPULSE is a novel method for detecting affective responses to dynamic audiovisual content. It is an implicit reaction time test that is carried out while an audiovisual clip (e.g., a television commercial) plays in the background and measures feelings that are congruent or incongruent with the content of the clip. The results of three experiments illustrate the following four advantages of IMPULSE over self-reported and biometric methods: (1) being less susceptible to typical confounds associated with explicit measures, (2) being easier to measure deep-seated and often nonconscious emotions, (3) being better able to detect a broad range of emotions and feelings, and (4) being more efficient to implement as an online method.
In Vitro Diagnostic Assays for COVID-19: Recent Advances and Emerging Trends
Authors: Vashist Sandeep Kumar
Published: April 2020

There have been tremendous advances in in vitro diagnostic (IVD) assays for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The main IVD assays used for COVID-19 employ real-time reverse transcriptase polymerase chain reaction (RT-PCR) that takes a few hours. But the assay duration has been shortened to 45 min by Cepheid. Of interest is the point-of-care (POC) molecular assay by Abbott that decreased the assay duration to just 5 min. Most molecular tests have been approved by the United States Food and Drug Administration (FDA) under emergency use authorization (EUA) and are Conformité Européenne (CE) marked. A wide range of serology immunoassays (IAs) have also been developed that complement the molecular assays for the diagnosis of COVID-19. The most prominent IAs are automated chemiluminescent IA (CLIA), manual ELISA, and rapid lateral flow IA (LFIA), which detect the immunoglobulin M (IgM) and immunoglobulin G (IgG) produced in persons in response to SARS-CoV-2 infection. The ongoing research efforts and advances in complementary technologies will pave the way to new POC IVD assays in the coming months. However, the performance of IVD assays needs to be critically evaluated before they are employed for the clinical diagnosis of COVID-19.
Lupus Eritematoso Sistêmico Infanto-Juvenil: Comprometimento Neurológico
Authors: Schmutzler Kátia Maria Ribeiro Silva
Published: April 2020

.
Knowledge, Attitude and Practices Regarding Extreme Environments and Cold Adaptation at Extreme Altitudes on the Himalayan Ranges
Authors: Khan Inam Danish
Published: April 2020

Introduction: Extreme-altitudes (5500 m/18045 ft and higher) pose environmental, psychophysiological, infrastructural, logistic, and ergonomic challenges that question explorer’s adaptability and mission-efficiency due to isolation, monotony, intimidating environment and terse health conditions. The assessment of an explorer’s comprehensive adaptability in extreme-altitudes is of paramount importance in ensuring mission-preparedness. Knowledge, attitude, and practices (KAP) of explorers staying on extreme-altitudes was assessed through personal interview technique. Methods: 125 healthy, acclimatized, mountain-trained explorers staying above 4570 m/15000 ft in winter-season for at least 30 days on extreme-altitudes were assessed by a single cross-sectional study through personal interviews on KAP related to extreme-altitude and cold-adaptation. Results: Mean duration of stay on extreme-altitude was 55.7 days. All explorers knew about difficulties and health-problems at extremealtitude. All explorers felt that mountain-training and acclimatization were beneficial. 92% felt that mission tenure of 90 days on the extreme-altitude was adequate. 92.8% felt they were adequately trained for the extreme-altitude; however, only 52% felt confident about health-training. 66.4% did preventive rewarming of extremities. 66.4% regularly smoked/chewed tobacco. 57.6% had sleep problems and 64% had altered appetite. 26.4% felt difficulties related to living conditions, infrastructure, and logistics. Conclusion: Explorers at extreme-altitude exhibited adequate knowledge and performed activities with progressive attitude and healthy practices. Explorers endured altered psychophysiology at extreme-altitude and regarded the utility of training and acclimatization programs. Knowledge-practice gap existed towards tobacco consumption. There was a felt need for the improvement of living conditions, infrastructure, logistics, and health-related training.
Assessment of Risk of Type 2 Diabetes Among Adults of Banepa Municipality, Nepal: Community Based Cross-Sectional Study
Authors: Thapa Sailendra , Kayastha Pratigya , Mishra Durga Khadka
Published: April 2020

Introduction: The prevalence of type 2 diabetes has been escalating worldwide, including low- and middle-income countries such as Nepal. Early detection of individuals at risk is of the utmost importance to prevent the escalating condition. This study used a simple, cost-effective screening tool known as the Indian Diabetes Risk Score (IDRS) in order to assess the proportion of risk groups and factors associated with it among the residents of Banepa municipality, a semi-urban area of central Nepal. Methods: A community-based cross-sectional study was conducted among 245 adults of Banepa municipality. Face to face interviews were conducted to collect the information through a pretested, semi-structured questionnaire. IDRS was used to identify the risk group for developing type 2 diabetes. Data were entered in Microsoft Excel 2010 and exported to SPSS v.11.5 for further analysis. Results: The proportion of people with high risk, moderate risk and low risk was 31%, 51.4% and 17.6%, respectively for developing type 2 diabetes. The analysis showed age (P < 0.01), education (P = 0.05), marital status (P = 0.01), body mass index (BMI) (P < 0.01), waist circumference (P < 0.01), physical activities (P < 0.01) and family history of diabetes (P < 0.04) were significantly associated with risk of type 2 diabetes. Conclusion: Nearly one-third of the study participants were in high-risk group and half of them were at moderate risk. This increasing trend of risk requires an urgent application of preventive measures through lifestyle modification.
Da leitura de uma picture à imagem de uma teoria: metaimagens da Rede Minas
Authors: Rocha Simone Maria , Resende Olívia Érika Alves
Published: April 2020

O objetivo deste artigo é o de captar, através da picture disponível na seção “Cultura” do site da Rede Minas de Televisão, qual é a possível imagem da audiência desta TV pública. Nossa preocupação inscreve-se no movimento contemporâneo de interrogação sobre a imagem que redundou na construção do campo interdisciplinar de estudos de cultura visual, segundo o qual é preciso que se adote um gesto pós-linguístico de dar imagem à teoria e se dedique às formas de ver e mostrar inscritas em nosso cotidiano. Metodologicamente, a análise do composto imagem/texto nos conduziu a uma metaimagem de dupla dimensão. Na primeira, a picture nos revela as estruturas conceituais e políticas que sustentam o fazer televisivo empreendido pela Emissora e, na segunda, ao mostrar o reflexo vazio de um espelho, a picture nos devolve o questionamento sobre a audiência da Rede Minas.
A Use Case of the Application of Advanced Gaming and
Immersion Technologies for Professional Training: The GAMEPHARM
Training Environment for Physiotherapists
Authors: Pappa Dimitra , Papadopoulos Homer
Published: April 2020

Immersive technologies are gaining momentum in professional
training. Advanced AR/VR and gaming technologies allow for authentic
learning experiences that are close to real‑life conditions,
problems, and applications, something that can revolutionise fields
like medical training, which traditionally relied on textbook‑based
theoretical education and clinical placements. The present paper
discusses the application of advanced gaming and immersion
technologies for the continuous training of physiotherapists.
Presently, this professional group remains largely underserved by
online training services. The paper argues that the inherent
complexity of physical therapy training could be served effectively
by immersive learning innovations and professionals could benefit
greatly. The paper applies the Design Science Research Methodology
(DSRM) to design a suitable training solution for the promotion of
authentic, comprehensive learning. Our analysis targets and
consolidates the findings from three distinct pillars: (a) the
requirements of the application area in question; (b) the current
state‑of‑the‑art and emerging directions in game‑based professional
education and training; and (c) existing applications of game‑based
learning in the field of healthcare. Subsequently, the paper
consolidates the findings to produce the system requirements and
presents the design of a prototype training environment for
physiotherapists that builds on advanced gaming technologies. Within
the proposed system design, augmented reality modules are embedded
alongside the game simulation and virtual world environment to
provide participants with an authentic simulated game scenario in
which to immerse themselves.
Co‑Creativity through Play and Game Design Thinking
Authors: Arnab Sylvester , Clarke Samantha , Morini Luca
Published: April 2020

This article discusses the application of game design
thinking as a learning process for scaffolding co‑creativity in
Higher Education based on the GameChangers initiative
(gamify.org.uk) part‑funded by the Higher Education Funding Council
of England (HEFCE). Taking into account the relationship between
play, technology and learning, the game design thinking approach
fully embraces and accommodates for the creation and development of
games of any typology (board games, card games, digital games, etc.)
and playful solutions (gamified products) as freely chosen by the
learners, aligning with the importance of autonomy, relatedness and
purpose in motivating learners to be deeply engaged in the process.
Through this process, learners are expected to gain valuable
knowledge in creative and collaborative problem solving and
experience game design and development process towards addressing
real challenges and opportunities in their communities. The focus of
the process is on the creative process rather than the end
products/solutions produced by the learners. The paper will
specifically discuss the methodology and findings from an
experimental module developed based on the approach involving four
cohorts of Level two undergraduate students (n=122, 2017‑2019). The
students came from the different schools and faculties at Coventry
University, UK. Based on the qualitative feedback and reflections
collected through the Module Evaluation Questionnaire (MEQ) and the
final reflection pieces, the co‑creative process inspired by play
and games demonstrates that through the process, students discover
the importance of elements such as empathy, purpose, meaning, art,
creativity and teamwork in their learning regardless of the specific
disciplines they are pursuing.
الاجتهاد في تقديم الراجح عند الشيخين: دراسة تحليلية في أحاديث الصحيحين
Authors: الحريري عمار أحمد
Published: April 2020

الإمام البخاري والإمام مسلم من أوائل من أفرد الحديث الصحيح بالتصنيف، وانشغل العلماء في دراسة اجتهادهما وفِقْه التعامل مع كتابيهما، ومن ذلك مسألة تقديم الراجح عند الشيخين، فالأصل في عملهما الاتفاق على تقديم الراجح والأصحِّ عند التعارض، ومع ذلك اختلف الشيخان في تقديم الراجح، فبعض ما رجّحه البخاري في صحيحه؛ خالفه مسلم فيه وتبنّى المرجوح عند البخاري، واعتمد كل منهما على عدة مرجّحات وقرائن استأنس بها الشرّاح لبيان اجتهاد الشيخين.

يدرس هذا البحث سبب اختلاف الشيخين في تقديم الراجح، وعدم تمكُّنِهما أو تمكُّنِ أحدهما من الترجيح، فرويا الحديثين المتناقضين دون الإشارة إلى أيهما الراجح أو المرجوح. ولكن مما أشكل أكثر ما فعله الشيخان أو أحدهما في بعض الأحاديث، حيث قُدَّم الراجح ورُوِي المرجوح. وأثمرت الدراسة عدة نتائج مهمة، تدل على منهج الشيخين الاجتهادي في تقديم الحديث الراجح، وعلى نسبية المرجحات وتعارضها، فرويا بعضها للتعليل أو لنكت حديثية.
ESTIMATION OF THERMODYNAMIC ISOTHERMS FOR MN ADSORPTION IN SOME CALCAREOUS SOILS AT SULAIMANI GOVERNORATE.
Authors: & et al. Abdullah
Published: April 2020

This study was conducted to determine the description of Mn adsorption phenomena through adsorption isotherms in some calcareous soils at Sulaimani governorate. Soil samples were taken at 0-30 cm depth from five different agricultural locations. Duplicate 1 gm of soil samples were equilibrated at 298 and 318°K with 50 ml of 0.01M CaCl2 containing (0, 2.5, 5, 10, 20, and 40) mg Mn L-1 as (MnSO4. H2O). The concentration of Mn determined in solution by using ICP-OES. The amount of Mn adsorbed by each soil samples was calculated. The thermodynamic parameters ΔH°, ΔG°, ΔS° were determined using adsorption data and concentration of Mn in equilibrium solution at two different temperatures. The results indicated that the Freundlich equation is the best model to describe Mn adsorption in studied soils due to the result the higher (R2), with lower (RMSE) and (AIC). The results of (ΔH°) indicated that the Mn adsorption processes in the Sharazor, Qaradagh and Mawat soils were exothermic reactions. While, the Mn adsorption processes in both Bazian and Surdash locations were endothermic reactions. The (ΔS°) values of these soils were as follows: Surdash > Bazian> Sharazor > Qaradagh > Mawat. The results of (ΔG°) indicated that the reaction in all studied soil locations at temperature 298 °K is spontaneous, also the reaction stay spontaneous with increase temperature to 318°K only in both Bazian and Surdash locations.
PREPARATION OF JUNIPERUS EXTRACT AND DETECTION OF ITS ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY
Authors: &et al. Maeh
Published: April 2020

This study was aimed to produce silver nanoparticles by fruits extract of Juniperus phoenicea and comparison between the ethanolic extract and nano extract through the antioxidant, antibacterial, anti-parasite and cytotoxicity against prostate cancer. The synthesis of silver nanoparticles was shown by many characterizing techniques: UV, FTIR, XRD and SEM. Nano extract exhibited a higher antibacterial, antioxidant, antiparasite compared to ethanolic extract and higher cytotoxicity activity. The nano extract exhibited higher antibacterial activity compared with antibiotics. Finally, we study the toxicity of J. phoenicea by Inhibition of RBC hemolysis by H2O2, the results exhibited the highest inhibition activity of J. phoenicea against H2O2. The nanoextract of J. phoenicea can be used effectively in the production of potential antioxidant, antiparasite antimicrobial and anticancer.
PENGEMBANGAN GURU PROFESIONAL MENGHADAPI GENERASI ALPHA
Authors: Setyo Widodo Ganjar , Sita Rofiqoh Kharisma
Published: April 2020

Sebagaimana peserta didik, pengembangan guru juga perlu dilakukan apalagi seorang guru sebagai pendidik profesional bertugas untuk mendidik, mengajar, membimbing, mengarahkan, melatih, menilai, dan mengevaluasi peserta didik. Seorang Guru professional di era milenial atau Generasi Alpha, tidak cukup hanya mengusai kompetensi guru yang empat, yakni kompetensi pedagogik kepribadian professional dan sosial. Perkembangan teknologi informasi yang begitu pesat mengharuskan seorang guru menjadi bagian dari kemajuan teknologi tersebut. Metode penelitian yang digunakan adalah deskriptif analisis. Penelitian deskriptif analitis mengambil masalah atau memusatkan perhatian kepada masalah-masalah sebagaimana adanya saat penelitian dilaksanakan, hasil penelitian yang kemudian diolah dan dianalisis untuk diambil kesimpulannya. Hasil dan temuan memperlihatkan bahwa guru sebagai generasi Alpha kita harus memberikan teknik-teknik pendekatan yang sesuai dengan zaman sekarang. Guru dituntut untuk bisa mengikuti perkembangan teknologi sehingga dalam proses pembelajaran di kelas dapat di terima dan diikuti oleh peserta didik sekaligus dapat memanfaatkan potensi yang sudah dimiliki peserta didik. Guru harus banyak belajar bagaimana mengajar, yaitu tentang bagaimana lebih banyak mendesain sejumlah aktivitas atau model pembelajaran yang cocok untuk generasi Alpha.
Physical Exercise as Medicine for Self-Injurious Behavior
Authors: Ali Asif , Azam Muhammad , Mattiullah Jawairiyah
Published: April 2020

Self-injurious behavior is one of the leading causes of death worldwide. Anxiety, substance abuse, posttraumatic stress disorder, trauma, depression, and personality disorders are commonly reported in patients with self-injurious behavior. The primary purpose of this article is to present a summary of research examining the effectiveness of exercise to reduce self-injurious behavior and to recommend directions for further research. Major research databases including PubMed, Scopus, Science Direct, Taylor & Francis, Google Scholar, PsycINFO, MEDLINE, and ERIC were searched for published work. Only five studies were found relevant to the topic of our interest: one retrospective case study, two cross-sectional studies, and two interventional/experimental studies. The results of interventional studies found beneficial effects of aerobic exercise for reduction in self-injurious behavior. In addition, cross-sectional studies found effectiveness of moderate to vigorous exercise for self-injury. The findings also showed that exercise appeared to reduce negative psychological conditions and improve overall psychological states in people with self-injurious behavior.

[
Psychiatr Ann
. 2020;50(4):167–177.]
Liquefaction Susceptibility of Silty Sands and Low Plastic Clay Soils
Authors: Akhila M.  , Rangaswamy K.  , Sankar N.
Published: April 2020

The present study evaluates the liquefaction susceptibility of non-plastic silty sands and low plastic clay soils at different cyclic stress levels under undrained triaxial loading conditions. Six different types of soil combinations were prepared after blending the silt and clay fractions into the fine sand. Silty sands contain up to 40% non-plastic fines and low plastic clays comprise 10-20% clay fraction. The cylindrical soil specimens were constituted at the medium relative density and isotropically consolidated at 100 kPa pressure. The consolidated specimens were subjected to cyclic stress amplitudes of 0.127, 0.152 and 0.178 using sinusoidal wave loading at a frequency of 1 Hz. Results were presented in terms of pore pressure build-up and axial strain propagation with load cycles, and liquefaction resistance curves. It was found that the non-plastic silty sands and soil mixtures with plasticity indices up to 15 are more susceptible to liquefaction than the fine sands. The criterion on liquefaction susceptibility of low plastic soil mixtures shows that the soil mixtures with plasticity indices up to 15 containing 20% plastic fines exhibit a sand-like behavior and show higher liquefaction susceptibility than fine sands. It is worthy to note that the low plastic soil mixtures with PI ≥ 10 are more resistant to liquefaction than the silty sands (those contain up to 40% non-plastic fines).
Pushover Analysis of Base Isolated RC Frame Buildings With Masonry Infills
Authors: Nanda Radhikesh Prasad , Majumder Subhrasmita
Published: April 2020

In the present article, the performance of base-isolated infilled frames is studied analytically. The seismic performances of four RC buildings, namely RC bare frame without isolator, RC bare frame with isolator, RC infilled frame without isolator, and RC infilled frame with isolator are analysed. The results show a decrease in base shear value and increase in time period due to base isolated buildings, while these parameters are reversely affected due to infills. The decrease in story drift for the base isolated buildings is in phase while considering infill. Also, it can be inferred that plastic hinge formation is greatly affected by the introduction of masonry infill. Hence, relying on base isolation without considering infills may underestimate the seismic performance.
Effectiveness of a novel oral combination of D-Mannose, pomegranate extract, prebiotics and probiotics in the treatment of acute cystitis in women
Authors: Pugliese Dario , Acampora Anna , Porreca Angelo , Schips Luigi , Cindolo Luca
Published: April 2020

Objective: Urinary tract infections (UTIs) are defined as the symptomatic presence of pathogens in the urinary tract that are typically diagnosed by microscopy and culture of urine samples. Over the long-term antibiotic courses, alternative prophylactic methods as probiotics, cranberry juices and D-mannose have been introduced for recurrence prevention. The present study aimed to determine whether a new combination of D-Mannose, Pomegranate extract, Prebiotics and Probiotics is effective in modifying symptoms reported by women with acute uncomplicated acute cystitis. Material and methods: This is a pilot study, performed between September 2018 and November 2018 at the Department of Urology of Villa Stuart Private Hospital. A dose of a new combination of agents was administered twice daily for 5 days and then once a day for 10 days. Together with the compound, forced hydration (> 2 liters/day) has been strongly suggested. Antibiotics were permitted only in case of clinical worsening. Changes in patients’ symptoms, the therapeutic effects and changes in quality of life (QoL) were evaluated clinically and through a validated questionnaire, the Acute Cystitis Symptom Score (ACSS) at the first visit (T0), 15 (T1) and 30 (T2) days later. Results: Thirty-three patients were enrolled in the study (mean age 38,1 ± 11.2 years) and all completed the treatment protocol. At T1 visit, all symptoms or the majority of symptoms went off in 10 women (30.3%) and at T2 in 30 women (90.9%); some symptoms still remained in 16 women (48.5%) at T1 and in 3 women (9.1%) at T2; the persistence of all symptoms or the worsening of the condition was observed in 7 patients (21.2%) at T1 and in none at T2. The mean score reported at all the ACSS sub-scales significantly decreased between baseline and T1 and T2. Typical symptoms decreased from 11.5 (10.5-12.6) to 4.9 (4.0-5.9) and to 2.7 (2.1-3.3) (p-values < 0.0001); differential symptoms decreased from 3.1 (2.6-3.6) to 0.6 (0.3-0.9) and to 0.3 (0.1-0.5) (p-values 0.009 to < 0.0001); QoL mean score also decrease from 7.2 (6.7- 7.7) to 4.0 (3.3-4.6) and to 1.7 (1.2-2.1) (p-values < 0.0001). Six patients required antibiotics and no adverse events were recorded. Conclusions: Our study suggests that the action of the compounds, administered in this new combination, could help in an effective management of symptoms of acute cystitis in women, without antibiotics, in a wide majority of the cases. Lack of microbiological assessment is a clear limitation of the study. Moreover, lack of a control group is another important limitation. Finally, hyperhydration could have been a confounding factor in interpretation of results.
Sentidos do (e no) Ensino de Física no Ensino Médio: articulações com a teoria histórico-cultural
Authors: Pereira Marta Maximo
Published: April 2020

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A lógica interna das lutas corporais: implicações iniciais para o ensino-aprendizagem-treinamento do brazilian jiu-jítsu
Authors: Schmidt Vagner Augusto de Oliveira , Ribas João Francisco Magno
Published: April 2020

Visto somente como um meio de proteção e autodefesa, o Brazilian Jiu-jítsu passou a integrar diferentes materiais pedagógicos referentes a Educação Física. Entretanto, seu processo de ensino-aprendizagem-treinamento tem pouca fundamentação teórica. Nessa perspectiva, a presente pesquisa tem como objetivo refletir a respeito da Lógica Interna de interação do Brazilian Jiu-jítsu, sob as lentes da Praxiologia Motriz, a fim de apresentar suas contribuições para o processo de ensino-aprendizagem-treinamento. Para isso, foi realizada uma pesquisa bibliográfica, de cunho exploratório, com o intuito compreender a lógica sociomotriz de oposição e as comunicações práxicas pertinentes a essa prática corporal, possibilitando ao professor novas possibilidades para o ensino desta.
Avaliação do autoconceito físico em pessoas com deficiência: uma revisão sistemática
Authors: Vaz Junior Arnaldo , Mouad Mariana , Grubertt Guilherme Alves , Serassuelo Junior Helio
Published: April 2020

O presente estudo tem como objetivo revisar sistematicamente o estado da arte do autoconceito físico (ACF) de pessoas com deficiência (PCD) adultas e identificar instrumentos para análise deste constructo. Como procedimentos metodológicos, adotou-se as recomendações do PRISMA FlowDiagram e classificação de artigos conforme critérios de qualidade adaptados do instrumento STROBE. Foram realizadas buscas em diferentes bases de dados, compreendendo todo o período de existência das bases até 2019, chegando à análise final do estudo 11 artigos. Os resultado obtidos através da literatura demonstraram que o grupo deficiência intelectual apresentou α= 0,67-0,82 e o grupo deficiência física α= 0,64-0,85. Ademais, a prática de exercícios físicos apresenta correlação direta com o ACF e, identificou-se seis instrumentos de avaliação do ACF em PCD, sendo dois validados. Conclui-se que a prática de exercícios físicos tem relação direta com o ACF e há escassez de instrumentos validados que avaliem o ACF de PCD.
Living Philosophy: Self-revelation and Damaris Masham’s Philosophical Autobiography
Authors: Webb Simone
Published: April 2020

The seventeenth-century philosopher Damaris Masham (1658/59–1708) had an intimate and emotional relationship with her friend and companion John Locke (1632–1704), and corresponded with him over many years. Her extensive surviving letters to Locke have been largely overlooked by scholarship on her philosophy. Setting Masham’s letters in the context of philosophical and historical scholarship on autobiography, as well as Berel Lang’s work on philosophical genre, I argue that her letters to Locke should be read as a form of philosophical autobiography. By doing so, unrecognized aspects of Masham’s philosophical position on selfhood and sociability are made visible. Furthermore, I show how the personal and the philosophical are inextricable in the letters and argue that lived emotional experience is of philosophical value. This point is of particular import in the project of retrieval of women philosophers throughout history, but should also be taken into account in the context of a modern philosophical milieu that often privileges “arguing that” as the only legitimate mode of philosophical practice.
The Role of Universities of Georgia in Providing Continuing Education Courses of Local Self-Government Public Servants
Authors: Kordzadze Maka
Published: April 2020

The present-day rate of development of the society and technologies in any sphere requires from the employee constant raising of qualification and gaining new knowledge and skills – continuous professional development. Life-long learning, continuing education is equally important compared with initial degree education. This leads to the necessity of ensurng continuing education in especially significant areas for the country in which the country’s  leading universities have to be actively involved. Provision of continuing education for local self- government public servants in recent years in the context of the self - government reform gained special actuality in Georgia. The aim of the article is to underline the significant role of universities of Georgia in developing and providing continuing education courses to public servants of local self-government and identifying those measures which will promote active involvement of universities in this process.
RUSSIAN’S PROVING GROUND IN SYRIA
Authors: Nawrotek Jarosław
Published: April 2020

Mission of the Russian Federation Armed Forces in Syria is their biggest foreign military operation of current times. It became a form of evaluation of combat efficiency for different forces and troops. Moreover, the Russian Army could check the newest types of used munitions in combat conditions. Leading a combat operation far beyond the borders of own territory can be used for evaluation of the overall system safeguarding the combat operations theatre, and especially the logistics. What is more, the combat experience acquired by a few dozen thousand soldiers is also a priceless value for the army.
Oral Presentations at the 10th Canadian Conference on Dementia (CCD) Québec City, October 3, 2019
Authors: Services Conference
Published: April 2020

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Oscar Abril Ascaso
Authors: Albadalejo Carlos , Porta Laura
Published: April 2020

Pere Soldevila, gerente de la galería de arte Metropolitana Barcelona y Oscar Abril Ascaso, co-comisario de exposiciones de Sonar y programador del Centro de Arte Santa Mónica de Barcelona nos explican su particular visión del arte digital y de su situación actual en España.
Effect of Various Sources of Zinc and Iron on Dry Matter Yield, Nutrient Content and Nutrient Uptake of Finger Millet (Eleusine coracana l.)
Authors: Kumar E. Ajay , Surekha K. , Rekha K. Bhanu , Sharma S. Harish Kumar
Published: April 2020

A field experiment was conducted during Kharif 2018 at College Farm, College of Agriculture, PJTSAU to evaluate the effect of various sources of zinc and iron on dry matter yield, nutrient content and nutrient uptake of finger millet. This experiment was conducted with randomized block design with 14 treatments and replicated thrice.The results revealed that application of different Zinc and iron sources at different rates significantly influenced the dry matter yield, nutrient content and nutrient uptake of finger millet. The highest dry matter production was reported with T10 - application of  RDF (60:40:30 kg N,P2O5 and K2O kg ha-1)+ foliar application of FeSO4 @ 0.5% twice at 30 and 60 DAS at all the stages followed by T14- (RDF+ foliar application of Fe-humate @ 0.25% twice at 30 and 60 DAS). Nutrient content decreased and Nutrient uptake (Nitrogen, phosphorous, potassium, iron and zinc) by the crop steadily increased with advancement in age of the crop upto harvest. The treatment receiving (T10) RDF+ foliar spray of FeSO4 @ 0.5% twice at 30 and 60 DAS recorded the highest nutrient content and (N, P, K & Fe) uptake by crop at 30DAS, 60 DAS and at harvest followed by (T14) RDF+ foliar application of Fe-humate @ 0.25% twice at 30 and 60 DAS. While, the Zinc content and uptake by crop at 30 DAS, 60 DAS and at harvest was highest with the treatment receiving (T8) -RDF + Zn-Humate foliar spray @ 0.25% twice at 30 and 60 days after sowing and was followed by treatment T7-RDF + Zn-Humate soil application @ 42 Kg ha-1.
Dry Season Composition and Abundance of the Anopheles, Culex and Aedes Genera in Makrudi Benue State
Authors: Omale Ameh Godwill , Obisike Victor Ugochukwu , Amuta Elizabeth U.
Published: April 2020

Mosquitoes are very important vectors of malaria, yellow fever, dengue and other diseases. Their unmitigated availability is key to the spread of parasites spread by their bites. This research was designed to find out the abundance of mosquitoes of the Anopheles, Culex and Aedes Genera in Makurdi Local Government of Benue state. Larva was collected from different water bodies in three (3) different locations that cover Makurdi representatively with the aid of a scoop spoon. Collected larva was stored in transparent plastic plates and transported to the insectarium, filtered into cleaner water by decantation, fed with baker’s yeast and grown into adult Mosquitoes in premade 16x16x16 inches cages. Adults were fed with sugar solution in cotton balls. Dead mosquitoes were stored in vials containing 70% ethanol.  Using the Photographic Guide to common mosquitoes of Florida, Mosquitoes were identified by microscopy. 537 Mosquitoes were identified of different Genera. Aedesgenera recorded the highest abundance of 34.64%, while Anophelesgenera has the least abundance with 31.10%. Culexgenera recorded an abundance of 34.26% in makurdi. NorthBank with 40.78%, recorded the highest number of mosquitoes of the three Genera under consideration. Logo II/Kanshio follows with 32.22% and Karmen, 27.00%, showed the least abundance. Based on this research, Mosquitoes showed relatively high abundance in Makurdi in the dry and windy harmattan season. This could be one reason malaria persists even in the dry seasons in makurdi.
Psychosomatic Phenomenon According to the Stages of Development
Authors: Ponciano Daniela , Klinger Ellen F. , Chiacchio Fernanda B. , Prado Daniely S. , Barros Davi A. , Araujo Warly N. , Arruda Maria Aparecida R. , Gurgel Gianfrancesco
Published: April 2020

The psychosomatic term, report to the item of psychological origin of certain organic diseases, affective repercussions of the state of physical disease on the individual and studies of mind-body relationships with emphasis on the explanation of somatic pathology. The term can also be understood, as an ideology about health, falling ill and about health practices, is a field of research on these facts and, at the same time, practice. Thus, the objective of this work is to discuss, from a literature review, the psychosomatic manifestations that occur in the development phases in the context of the psychology area. The study is methodologically based on the literature review. For this work, the bibliographic search of articles indexed to the VHL Portal (Virtual Library in Saude) and in the Web of Science was carried out. The disease is often an escape from a conflict situation or appears due to the need for attention and affection, need to be cared for. The psychosomatic approach decreases treatment time, avoids unnecessary complementary tests and abbreviates the patient's suffering.
Prevalence of Side Effects, Drug Interaction among Patients Taking Statin in Turaif, Saudi Arabia
Authors: Raja Maria Abdul Ghafoor , Alrawili Gharam Hamdan , Al-Otaibi Nawaf , Amjad Muhammad Wahab
Published: April 2020

Background: Statins perceived to have favorable safety profile. Although many people on statin therapy do well but no drug is without potential for side effects. Awareness about risks as well as benefits of drugs is needed particularly drugs which are used on wide scale like statins because even uncommon side effects can have significant health impact. 

Objectives of the Study: To determine side effects occurrence among Saudi patients taking statins and to evaluate drug-drug interactions in Saudi patients taking statins.

Methodology: Self administered cross sectional study conducted during a period of four months from October 2018 to January 2019 in Turaif general hospital, Saudi Arabia on random sample of 500 Saudi patients out of which 330 participants were included in the study which were taking different types of statins medication using self-administered questionnaire in Arabic language specially designed for the research purpose after obtaining verbal consent and the data analyzed by SPSS program.

Results: A total of 330 patients; 128 (39%) females and 202 (61%) males—participated in the study. The majority 165 (50%) were in the age-group of 50 – 59 years. Simvastatin was the most commonly used statin among study participants 136 (41%) followed by rosuvastatin 114 (35%). Among the participants, there were some patients who take drugs which have drug interactions with statins; there were 64 (19%) take Amlodipine with simvastatin, 13 (4%) and 6 (2%) take esomeprazole and ompeprazole respectively with statins. Only 9 (3%) reported that they were advised by pharmacist to avoid grape fruit. Majority of participants 309 (94%) reported neck pain, difficulty in walking, frequently fatigue after starting on statin. Also majority of participants 320 (97%) suffer from muscle pain after starting statins medications.

Conclusion: The percentage of statin related side effects in this study population is high especially myopathy. Also some patients in this study taking medications that have drug interaction with statins, Counseling to patient regarding statin therapy appear to be insufficient. So, this study indicate that there's a need for more efforts from the physicians and pharmacist to avoid prescribing or dispensing medication that have drug-drug interaction with statins and provide counseling to patients regarding their statin therapy.
Direct Observation of Bandgap Oscillations Induced by Optical Phonons in Hybrid Lead Iodide Perovskites
Authors: Guo Peijun , Xia Yi , Gong Jue , Cao Duyen H. , Li Xiaotong , Li Xun , Zhang Qi , Stoumpos Constantinos C. , Kirschner Matthew S. , Wen Haidan , Prakapenka Vitali B. , Ketterson John B. , Martinson Alex B. F. , Xu Tao , Kanatzidis Mercouri G. , Chan Maria K. Y. , Schaller Richard D.
Published: April 2020

Hybrid organic–inorganic perovskites such as methylammonium lead iodide have emerged as promising semiconductors for energy‐relevant applications. The interactions between charge carriers and lattice vibrations, giving rise to polarons, have been invoked to explain some of their extraordinary optoelectronic properties. Here, time‐resolved optical spectroscopy is performed, with off‐resonant pumping and electronic probing, to examine several representative lead iodide perovskites. The temporal oscillations of electronic bandgaps induced by coherent lattice vibrations are reported, which is attributed to antiphase octahedral rotations that dominate in the examined 3D and 2D hybrid perovskites. The off‐resonant pumping scheme permits a simplified observation of changes in the bandgap owing to the Ag vibrational mode, which is qualitatively different from vibrational modes of other symmetries and without increased complexity of photogenerated electronic charges. The work demonstrates a strong correlation between the lead–iodide octahedral framework and electronic transitions, and provides further insights into the manipulation of coherent optical phonons and related properties in hybrid perovskites on ultrafast timescales.
Diastereodivergent Synthesis of Bridged Tetrahydroisoquinoline Derivatives Catalyzed by Modularly Designed Organocatalysts
Authors: Jakkampudi Satish , Konda Swapna , Arman Hadi , Zhao John C.‐G.
Published: April 2020

The diastereodivergent synthesis of bridged 1,2,3,4‐tetrahydroisoquinoline derivatives has been achieved by using appropriate modularly designed organocatalysts (MDOs) that are self‐assembled in situ from amino acids and cinchona alkaloid derivatives. The domino Mannich/aza‐Michael/aldol reaction between (E)‐2‐[2‐(3‐aryl‐3‐oxoprop‐1‐en‐1‐yl)phenyl]acetaldehydes and ethyl or benzyl (E)‐2‐[(4‐methoxyphenyl)imino]acetates catalyzed by MDOs gives two different diastereomers of the desired bridged tetrahydroisoquinolines in good yields and excellent diastereoselectivities (up to 99:1 dr) and enantioselectivities (up to >99% ee). The diastereodivergence was achieved in the aldol reaction step.

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Therapeutic Effects of Anti–Bone Morphogenetic Protein and Activin Membrane‐Bound Inhibitor Treatment in Psoriasis and Arthritis
Authors: Alvarez Pilar , Augustín Juan Jesús , Tamayo Esther , Iglesias Marcos , Acinas Olga , Mendiguren María Angeles , Vázquez José Andrés , Genre Fernanda , San Segundo David , Merino Jesús , Merino Ramón
Published: April 2020

Objective

The transforming growth factor β (TGFβ) inhibitor BAMBI (bone morphogenetic protein and activin membrane‐bound inhibitor) has been shown to control differentiation of CD4+ T lymphocytes into either tolerogenic Treg cells or pathogenic Th17 cells, through the regulation of TGFβ and interleukin‐2 (IL‐2) signaling strength. The present study was undertaken to explore the potential beneficial effects of this strategy of pharmacologic inhibition using novel anti‐BAMBI monoclonal antibodies (mAb) in different experimental murine models of chronic skin and joint inflammatory/autoimmune disease.

Methods

Development of Saccharomyces cerevisiae mannan–induced psoriatic arthritis (MIP) (n = 18–30 mice per group), imiquimod‐induced skin psoriasis (n = 20–30 mice per group), or type II collagen–induced arthritis (CIA) (n = 13–16 mice per group) was analyzed in a total of 2–5 different experiments with either wild‐type (WT) or BAMBI‐deficient B10.RIII mice that were left untreated or treated with mAb B101.37 (mouse IgG1 anti‐BAMBI), a mouse IgG1 anti‐TNP isotype control, anti‐CD25, or anti‐TGFβ mAb.

Results

Treatment of normal mice with IgG1 anti‐BAMBI mAb clone B101.37 led to expansion of Treg cells in vivo, and had both preventive and therapeutic effects in mice with MIP (each P < 0.05 versus controls). The conferred protection against disease progression was found to be mediated by Treg cells, which controlled the activation and expansion of pathogenic IL‐17–producing cells, and was dependent on the level of TGFβ activity. Furthermore, treatment with B101.37 mAb blocked both the development of skin psoriasis induced by imiquimod and the development of CIA in mice (each P < 0.05 versus controls). Finally, pharmacologic inhibition of BAMBI with the IgM anti‐BAMBI mAb B143.14 also potentiated the suppressive activity of Treg cells in vitro (P < 0.001 versus controls).

Conclusion

These results in murine models identify BAMBI as a promising new therapeutic target for chronic inflammatory diseases and other pathologic conditions modulated by Treg cells.