bluuebunny/crossref_metadata_2025 huggingface dataset:
An affective (dis)ordering of difference: a practice approach to diversity, equity, inclusion, and access in veterinary medicine
Authors:   , Branton Scott E., II
Published: February 2023

Recent organizational theorizing contends that ontological assumptions around diversity, equity, and inclusion (DEI) must be reconsidered. I argue that an underlying assumption of separation within the prevailing approaches to DEI theorizing and practice contributes to the ongoing persistence of inequity within the workplace and organizations. Relationality not only demonstrates how separation is produced and reproduced in research and practice, but how scholars can rethink ontological assumptions surrounding diversity and inclusion. Utilizing participant observation, interview techniques, and document analysis at a college of veterinary medicine and affiliated teaching hospital, this study combines practice theory, communication constitutes organizing (CCO), and affect theory. Four themes emerged from the analysis: affective economy of veterinary identity, atmosphere of whiteness, disordered attunement, and neutrality of practices.
Does the Campus Pride Index reflect lived experiences? A qualitative and minority stress approach to studying LGBTQ students in student life and housing and residence life
Authors:   , Joseph Thomas A.
Published: February 2023

[EMBARGOED UNTIL 8/1/2023] The Campus Pride Index (CPI) evaluates institutions' inclusivity relative to LGBTQ students, faculty, and staff in eight categories. This study targets two of them, Student Life (SL) and Housing and Residence Life (HRL), and considers the experiences of LGBTQ students. The research infused minority stress theory throughout the interview protocol to determine how each area affects an LGBTQ student's mental and physical health. The major findings of this study were that though a sense of belonging did exist, it was due to the relationships built amongst fellow LGBTQ students and not the institution itself. Furthermore, students felt CPI scores were misleading and that minority stress impacted student mental health in various ways. This research is relevant to college-seeking students, current enrollees, senior administrators, and Campus Pride. Implications of this study are far-reaching in that research data disputes published inclusivity scores in the CPI and demonstrate significant areas where this institution is failing its LGBTQ students.
Geochronologic and thermochronologic constraints on the mesozoic to cenozoic deformation history of
southeastern california
Authors:   , Ludwig Katherine G.
Published: February 2023

[EMBARGOED UNTIL 8/1/2023] Southeastern California hosts a complex zone of deformation defined by structures related to the San Andreas fault, such as the sinistral Garlock fault and the largely dextral eastern California shear zone, as well as extensional structures of the Basin and Range province. This study aims to better understand how these tectonic regimes interact in the area around Death Valley. Apatite and zircon (U-Th)/He data from two transects in the Kingston and Mesquite ranges are first used to explore the Cretaceous to Pliocene exhumation history of the footwall of the oldest detachment system associated with the southern Death Valley area, the Kingston Range--Halloran Hills detachment. Apatite (U-Th)/He data were also collected from the Kingston Peak pluton, which has played an integral role in the development of the detachment. A nearby structure, the Southern Death Valley fault, is also investigated. This fault zone extends south through Death Valley and intersects with the Garlock fault, but its extent past this intersection and the displacement accommodated by this structure has been debated. Previous studies suggest that the fault extends south of the Garlock fault and continues to accommodate displacement there. A previous study proposed that Miocene strata in the Avawatz Mountains, located at the intersection of the Garlock and southern Death Valley faults, may be sourced from the Halloran Hills, which are now 20 km to the south, suggesting that the southern Death Valley fault extends that distance and has accommodated at least an equivalent amount of displacement. To test this hypothesis, this study uses detrital zircon U-Pb dating of two formations proposed to have shared provenance to establish depositional ages and sediment sources of the units. The results show that these formations are not related and cannot be used as evidence for a continuation of the southern Death Valley fault. Finally, new zircon (U-Th)/He data and existing thermochronology data constrain the exhumation history of the Avawatz Mountains, which uplift at the intersection of the Garlock and Southern Death Valley fault zones. These data record exhumation related to Mesozoic thrusting and subsequent extensional collapse or erosional exhumation, as well as Miocene uplift. Thermal models support a Middle Miocene initiation date of the Garlock fault zone as well as a Late Miocene initiation date of Southern Death Valley fault zone.
Emergency Treatment of Soft Tissue and Dentoalveolar Fractures using Risdon Wiring in Children due to Motorcycle Accident : Case Report
Authors: Sjamsudin Endang , Yazid Y Harmas , Tasman Abel , Priyanto Winarno
Published: February 2023

Introduction: Dentoalveolar fractures are often found in children due to physical trauma, falls, and motorized accidents. In pediatric patients, there are variations in age, jaw development, and dentition which are the primary considerations in choosing a dentoalveolar fracture treatment method. This case report aims to describe and discuss the emergency management of soft tissue injuries and mandibular dentoalveolar fractures with Risdon wiring in pediatric patients due to motorized accidents.
Case report: A 9-year-old female patient complained of bleeding from the mouth due to a traffic accident. Clinical and radiographic examination showed dentoalveolar segment fractures in tooth region 32-42, stab wounds, and lacerations on the inferior lip, vestibule, and gingiva in tooth region 32-42. The patient underwent wound cleaning, wound suturing, and treatment of dentoalveolar fractures with fixation using Risdon wiring in the mandibular region 36-46.
Conclusion: Conservative treatment of dentoalveolar fractures in pediatric patients with minimal intervention can give good results. Risdon wiring as a fixation method can be used in the emergency treatment of dentoalveolar fractures in pediatric patients with mixed dentition.
Keywords: Soft tissue trauma, dentoalveolar fracture, Risdon wiring, emergency
The Effect of Snake Venom (Naja Naja Oxiana) on Proliferation Rate of cancer Cells
Authors:   Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran Medical sciences, Islamic Azad university,Tehran, Iran., Zafari Jaber , Javani Jouni Fatemeh ,   Department of Biomedical Engineering, Faculty of Health, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Shams Elaheh ,   Behbahan Faculty of Medical Sciences and Health Services, Behbahan, Iran., Rastegari Ali Asghar ,   Department of Molecular and Cell Biochemistry, Faculty of Biology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.
Published: February 2023

Aims Because cancer is the leading cause of death worldwide, finding a better way to treat it seems essential. Doxorubicin is one of the most common drugs in the treatment of cancer, which has many negative and toxic effects. Therefore, efforts to produce effective anticancer drugs through screening natural compounds, such as animal toxins continue. This study aimed to evaluate the effect of Naja naja oxiana snake venom in comparison with doxorubicin on the proliferation rate and concentration of malondialdehyde in the human cervical cancer cell line (HeLa) and fibroblast cells (HFF). Methods & Materials HeLa and normal fibroblast cancer cell lines were exposed to different concentrations of snake venom and doxorubicin for 24 and 48 hours. The amplification rate was determined using trypan blue staining and malondialdehyde (MDA) concentration was measured to evaluate the effects of oxidative stress. Data were analyzed using SPSS software, version 19. Findings The results showed that with increasing concentration and treatment time with snake venom and doxorubicin, the cell proliferation rate decreases, and MDA content increases. The highest decrease in proliferation rate and increase in MDA concentration were observed in the HeLa cancer cell line treated with 500 µg/mL of snake venom for 48 hours. Conclusion In comparison with doxorubicin, snake venom has a significant inhibitory effect on the HeLa cancer cell line with minimal effect on normal fibroblast cells.
The Effectiveness of Self-healing Training on Psychological Well-being in Women With Hypertension
Authors:   Department of Psychology, Payame Noor University, Tehran, Iran., Latifi Zohreh , Mardani Zahra ,   Department of Psychology, Payame Noor University, Tehran, Iran., Ghareghani Reyhaneh ,   Department of counseling, Payame Noor University, Tehran, Iran.
Published: February 2023

Aims: Hypertension is one of the most common health problems with chronic consequences. The present study aimed to investigate the effect of self-healing training on psychological well-being in women with hypertension. Methods & Materials: The research method was quasi-experimental with a pre-test, post-test, and two-month follow-up design and control and an experimental group. Thirty women with hypertension referred to the health centers were selected according to convenience sampling and randomly divided into experimental and control groups (n=15 per group). The research instruments included Ryff’s scale of psychological well-being (1989). Repeated measures were utilized to analyze the data. Findings: The results indicated that the mean total scores of the pre-test, post-test, and follow-up of psychological well-being scale in the experimental group were equal to 213.20, 219.98, and 220.08 respectively, and it was equal to 195.26, 197.33, and 200.06 in the control group. Also, self-healing training significantly increased psychological well-being in participants in the post-test and follow-up stages (P<0.05). Conclusion: The self-healing training increased psychological well-being in women with hypertension to strengthen the role of the individuals by reducing physiological stress, treating destructive cellular memories, lifestyle modification, and relaxation techniques. Therefore, this method can be used as a new approach with relatively lasting effects to increase the self-care skills of patients with hypertension in health-related centers.
Evaluation of Muscle Fatigue and Determination of Risk Factors of Musculoskeletal Disorders Among Saffron Harvesters in Gonabad in 2017
Authors:   Department of Occupational Health, Student Research Committee, Faculty of Health, Shiraz University of Medical Sciences, Shiraz, Iran., Emkani Mojtaba , Jafari Mostafa ,   Department of Occupational Health Engineering, Social Determinants of Health Research Center, Faculty of Health, Gonabad University of Medical Sciences, Gonabad, Iran., Mafakheri Lale Zahra ,   Department of Occupational Health, Student Research Committee, Faculty of Health, Gonabad University of Medical Sciences, Gonabad, Iran., Tabrizi Akram ,   Department of Occupational Health Engineering, Social Determinants of Health Research Center, Faculty of Health, Gonabad University of Medical Sciences, Gonabad, Iran.
Published: February 2023

Aims Musculoskeletal disorders (MSDs) are common in farmers due to the high workload in agriculture. Because several factors, such as physical, personal, and psychological factors in saffron harvesters can influence persons’ physical conditions and expose them to the risk of MSDs, the present study aimed to investigate muscle fatigue and determine the prevalence of MSDs and related factors among Gonabad saffron harvesters. Methods & Materials This cross-sectional study was performed on 84 saffron harvesters in Gonabad city, Iran. Data collection tools included a standard Nordic questionnaire to assess the prevalence of MSDs and the muscle fatigue assessment (MFA) method to assess body muscle fatigue. Finally, the data were analyzed using SPSS software, version 20. Findings The prevalence of MSDs in saffron harvesters in the shoulder, wrist, ankle, upper back, lower back, elbow, neck, thigh, and knee was 91.7, 90.5, 92.9, 8.48, 50, 88.1, 15.5, 50, and 47.6%, respectively. The results of the MFA evaluation also showed that the risk of muscle fatigue in the neck, right wrist, and right arm is very high in 98.8%, 49.4%, and 36.5% of employees, respectively. There was a significant relationship between MSDs in the past 12 months and age, sex, medical history, and working hours, and between muscle fatigue and age, smoking, and exercise (P<0.05). Conclusion The highest prevalence of symptoms of MSDs was in the shoulder, wrist, and ankle areas. Due to the significant prevalence of MSDs among saffron harvesters, it is necessary to consider ergonomic interventions, soft movements at regular intervals, and raising awareness in the form of educational programs.
Factors Related to the Acceptance and Rejection of COVID-19 Vaccination
Authors:   Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran., Pourshahri Erfan , Khajavian Nasim ,   Social Determinate of Health Center, Gonabad University of Medical Sciences, Gonabad, Iran., Bazeli Javad ,   Department of Emergency Medicine, School of Nursing and Midwifery, Gonabad University of Medical Sciences, Gonabad, Iran., Sadeghmoghadam Leila ,   Department of Nursing, Social Development and Health Promotion Research Center, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran.
Published: February 2023

Aims Despite various government measures, control of COVID-19 requires immediate action, including vaccine production. Given the role of vaccine acceptance factors in future planning, this study aimed to unfold the determinants of COVID-19 vaccine acceptance in Gonabad. Methods & Materials This descriptive-analytical study was performed on 292 people in Gonabad city, Iran, in 2021. The random multi-stage sampling method was used to select two groups of samples: Vaccinated and unvaccinated. The data collection tool consisted of a demographic checklist and a researcher-made questionnaire on the reasons for accepting or rejecting the COVID-19 vaccination. Data were collected by telephone and analyzed by SPSS software, version 23 using mean, standard deviation, and the Chi-square test at a significance level of less than 0.05. Findings Most of the research participants were women (51%). The Mean±SD age of the vaccinated and non-vaccinated groups was 57.55±12.24 and 55.38±41.1 years, respectively. Two factors of living with people at risk (88.5%) and respect for the rights of others (80.9%) were the most important reasons for accepting and worrying about the side effects of the vaccine (63%). Worrying about the content and lack of knowledge about the effectiveness of the vaccine (45.3%) were mentioned as the most important reasons for not accepting the COVID-19 vaccination. Conclusion Considering the importance of two factors, including the concern about the side effects of the COVID-19 vaccine and concern about the content and ineffectiveness of COVID-19 vaccine in rejecting COVID-19 vaccine, increasing public awareness and knowledge about the effectiveness of vaccines in the country seems necessary to plan and invest on a large scale in the country through reliable sources as well as efforts to reduce the fear of the consequences of vaccination.
Emergência da semiótica no pensamento de Félix Guattari
Authors: Santos Rogério da Costa
Published: February 2023

Este breve artigo observa os primeiros movimentos de Félix Guattari, desde seu texto “O Anti-Édipo” (1972), em parceria com Gilles Deleuze, em direção à semiótica de Charles Sanders Peirce. Com a aparição das primeiras referências ao filósofo americano, no livro “O inconsciente maquínico”, de 1979, já é possível perceber que a semiótica, tal como Peirce a elaborou, exerceria um papel essencial no pensamento do filósofo francês a partir do final dos anos de 1970.
ЗМІНИ ДО КРИМІНАЛЬНОГО КОДЕКСУ В УМОВАХ ВОЄННОГО СТАНУ: ДИСКУСІЙНІ ПИТАННЯ
Authors: Коваль А. А. , Самойленко М. С.
Published: February 2023

Статтю присвячено аналізу змін до Кримінального кодексу України (далі – КК), внесених під час воєнного стану. Акцентовано увагу на важливості впровадження в державі кримінально-правової політики, спрямованої на протидію злочинним проявам у суспільстві в умовах воєнного стану. Аргументовано неефективність деяких положень КК в сучасних умовах. Обґрунтовано потребу і причини змін до кримінального законодавства, які передбачають жорсткіші покарання порівняно з мирним часом. Доведена їх надзвичайна актуальність, дієвість та значимість в умовах воєнного стану. У статті звертається увага на такий недолік кримінально-правової політики як неврахування вчинення шахрайства в умовах воєнного або надзвичайного стану. Наводяться достатні підстави вважати, що в таких умовах значно підвищується ризик вчинення цього кримінального правопорушення. Тому висловлюється думка стосовно доцільності включення до переліку діянь, відповідальність за які має посилюватися у разі їхнього вчинення в умовах воєнного або надзвичайного стану, посягань, передбачених статтею 190 КК. Розглянуто дискусійне питання щодо ідентичності формулювань «використання умов воєнного або надзвичайного стану» як обтяжуючої обставини та вчинення відповідних діянь «в умовах воєнного стану» та зроблено спробу розмежувати ці два поняття. Роз’яснено, що зміни щодо відсутності кримінальної відповідальності за застосування вогнепальної зброї проти осіб, які здійснюють збройну агресію проти України, якщо така зброя застосована відповідно до вимог Закону, фактично уточнюють окремі положення розділу VIII ККУ «Обставини, що виключають кримінальну протиправність діяння». Наголошено на необхідності уточнення змісту статей 435-1 («Образа честі і гідності військовослужбовця, погроза військовослужбовцю») та 436-2 («Виправдовування, визнання правомірною, заперечення збройної агресії Російської Федерації проти України, глорифікація її учасників») КК через обмежене їх застосування у випадку втягування до воєнних дій на боці РФ і інших країн, і при цьому військовослужбовець України здійснюватиме заходи із забезпечення національної безпеки і оборони, відсічі і стримування збройної агресії інших держав. Пропонується застосувати більш узагальнююче поняття «держава-агресор».
Welfare contrattuale e sanità integrativa: Una prospettiva di relazioni industriali
Authors: Dalla Sega Michele
Published: February 2023

Il presente studio ha l'obiettivo di indagare le principali tendenze di sviluppo delle politiche di assistenza sanitaria integrativa nell'ambito della contrattazione collettiva. L'analisi viene compiuta su una selezione di 58 Contratti Collettivi Nazionali, focalizzando l'attenzione sulle specifiche previsioni sulla materia, al fine di verificare, da un lato, se vi siano dei "modelli" contrattual-collettivi di sviluppo dei Fondi sanitari, dall'altro lato, quali siano le principali misure garantite dagli stessi enti. Le prime evidenze emerse dai casi analizzati mostrano, in primo luogo, un processo di graduale accentramento delle risorse verso i grandi Fondi settoriali e intersettoriali promossi a livello nazionale. Sul piano delle prestazioni, invece, si nota come i Fondi operino principalmente nell'ambito di aree sanitarie già presidiate dal Servizio Sanitario Nazionale, piuttosto che con un fine realmente integrativo delle prestazioni pubbliche.
In tempore belli: etica e clinica nel campo della disumanità
Authors: Didkovska Inna , Kedrova Natasha , Mishchenko Max , Mione Maria , Pino Luca , Nora Pappalardo Giulia
Published: February 2023

L'articolo raccoglie lo sguardo di quattro autori che raccontano il loro essere terapeuti e "uomini" in un contesto difficile come l'attuale guerra russo-ucraina. I curatori dell'articolo hanno stimolato questa riflessione attraverso alcune domande pro-fondamente radicate nell'epistemologia gestaltica a partire dalla cura del ground che non è mai solo individuale, ma sempre co-creato e condiviso e all'attenzione al campo fenomenologico e sociale. Gli autori intervistati, due psicoterapeuti russi, di cui uno attualmente ospite in Italia, una ucraina e una italiana, hanno risposto partendo dalla loro esperienza diretta, raccontando perce-zioni e vissuti rispetto a come stanno attraversando la complessità che un evento del genere porta con sé. Clinica ed etica si intrecciano così nel rispetto del dolore e delle posizioni di ognuno. Le risposte dei terapeuti ci lasciano aperti alla speranza e ci ricordano che avere cura del dolore dell'altro è un atto che ha una ricaduta non solo sul singolo paziente, ma sull'umanità intera. Mantenere un atteggiamento umile e di prossimità nei confronti del dolore è la scelta etica capace di arginare le derive narcisistiche o individualistiche che si possono attivare in un campo complesso carico di angoscia e morte.
Radici e germogli: la psicoterapia della Gestalt e il trauma transgenerazionale
Authors: La Pietra Federica
Published: February 2023

Nel susseguirsi di eventi mondiali come la pandemia e la guerra, diviene fondamentale la necessità di affrontare, trattare ed elaborare le ferite delle esperienze traumatiche, in modo che non condizionino in senso definitivo la percezione del futuro. Viviamo in un'epoca storica di diffusa e intensa traumatizzazione e gli effetti di queste sofferenze rischiano di avere conse-guenze sulle future generazioni che, come abbiamo visto, non è scontato sappiano o possano imparare dalle esperienze passate. Alla luce di ciò, la psicoterapia è la chiave per un cambia-mento individuale e sociale e, come psicoterapeuti, siamo chiamati ad agire responsabilmente non solo nei confronti dei pazienti, ma verso l'intera comunità, occupandoci della diffusione del trauma nella società e della propagazione della violenza da una generazione all'altra.
Recensioni
Authors: Tosi Silvia , Bloom Dan , Melnick Joseph
Published: February 2023

- Dreitzel P. (2018). The Art of Living and the Joy of Life. Development and Maturity in a Changing World. Siracusa: Istituto di Gestalt HCCItaly Publ. Co. (www.gestaltitaly.com). ISBN: 978-88-989-1207-0, pp. 339, € 39,00

- Kato J., Klaren G., Levi N. (Eds.) (2019). Supporting Human Dignity in a Collapsing Field: Gestalt Approach in the Social and Political Contexts. Siracusa: Istituto di Gestalt HCC Italy Publ. Co. (www.gestaltitaly.com). ISBN: 978-88-989-1223-0, pp. 243, € 40,00
Eating disorders and adolescence. From diagnosis to treatment
Authors: Signorelli Annalisa
Published: February 2023

Eating Disorders (EDs) are potentially serious disabling, pervasive, and life-threatening mental disorders that can greatly impair physical health and significantly alter an individual's psychosocial functioning. They are some of the most prevalent disorders during adolescence and often take a chronic and disabling course, although they can occur across the whole lifespan. Prevalence appears to be higher in Western populations and in the female sex. They play a key role in the origin and maintenance of symptomatology, predominantly: distorted beliefs, distorted perceptions, dysfunctional attitudes toward weight, body shape, and nutrition, which take hold beginning in childhood or adolescence, but also genetic bases, socio-cultural and environmental factors. Given the complexity of the etiology of such psychopathologies and maintenance factors, treatment must contemplate a multidimensional and multidisciplinary approach. To date, the deep understanding of the pathophysiology and psychobiology of EDs remains to be further investigated.
Mitologías feministas y de la disidencia sexual: deformar sentidos y despolitizar por medio del humor
Authors: Bárcenas Barajas Karina
Published: February 2023

En este artículo se examina la manera cómo los memes disciplinarios —antifeministas y en contra de la disidencia sexual— que circulan en perfiles contra la “ideología de género” en México, constituyen prácticas de dominación simbólica que perpetúan modos de opresión. Siguiendo la perspectiva semiológica de Roland Barthes, los memes disciplinarios son analizados como mitologías, lo cual permite focalizar en tres de sus funciones ideológicas: deformar el sentido, naturalizar y despolitizar. La estrategia metodológica parte de la centralidad analítica de volver al archivo etnográfico.
A természeti erőforrások védelméről szóló sarkalatos törvények elfogadásának sorrendje és hatása a már kialakult földforgalmi joggyakorlatra
Authors: Olajos István
Published: February 2023

A cikk összefoglalja a természeti erőforrások jogszabályi védelme kialakításának folyamatát. A szerző arra törekszik, hogy bemutassa, hogyan hat vissza a családi gazdaságokról szóló törvény elfogadásával létrejövő 3 új gazdasági társaságtípus a földforgalmi törvény szövegére, és hogy hat a földforgalom már kialakult és elő szerződéseire. A tanulmány külön elemzi a sarkalatos földforgalmi törvénybe és a végrehajtásáról szóló jogszabályba beiktatott változásokat, a változtatások és a jogszabály értelmezésének egységét, valamint azt, hogy a változások milyen jövőbeli hatással bírnak a földhasználat szerkezetére.
Цифровий інструментарій кадрової складової системи економічної безпеки підприємства
Authors: Ніжегородцев В. О. , Петренко Л. М.
Published: February 2023

Кадрова безпека є однією зі складових економічної безпеки підприємства разом з іншими, такими як: фінансова, силова, інформаційна, технологічна, правова, екологічна. Об’єктом кадрової безпеки підприємства варто вважати негативні внутрішні ризики підприємства та загрози, пов’язані з діяльністю персоналу, а також зовнішні фактори, що знижують рівень кадрової безпеки. Сьогодні доцільно приділити увагу питанню управління безпекою персоналу як комплексу організаційних та технічних заходів, що знижують загрози безпеці персоналу на підприємствах. Серед існуючих засобів забезпечення безпеки підприємства можна виокремити інформаційні засоби. Корисними для поліпшення засад кадрової складової системи економічної безпеки підприємства, на нашу думку, можуть стати програмні інструменти з підтримки прийняття рішень. Серед програмного забезпечення підтримки прийняття рішень досить популярними є засоби аналізу рішень (Decision Analysis) та методи і програмне забезпечення «видобування даних» (Data Mining) – способу аналізу інформації у базі даних з метою відшукання аномалій і трендів без з’ясування значеннєвого змісту записів. На сьогодні вже доступні деякі основні державні електронні сервіси через мережу «Інтернет» за допомогою пошуку даних з різноманітних реєстрів, де можна отримати уніфіковані дані кадрової складової системи економічної безпеки підприємства. Запропоновані складові цифрового інструментарію щодо побудови ефективної системи економічної безпеки підприємства дозволять досягти найбільш високого рівня економічної безпеки.
Актуалізація і динаміка розвитку деглобалізаційних процесів та їх впливу на формування економічної політики
Authors: Онишко С. , Бєлін В.
Published: February 2023

Стаття присвячення дослідженню актуальної тенденції посилення деглобалізаційних процесів та зміни інтересів держави у сфері економічної політики. Потрясіння в торгово-економічному секторі внаслідок пандемії COVID-19 суттєво вплинули на експортно-імпортні відносини між окремими країнами. Аналізуючи динаміку зростання обмежувальних торгових заходів між країнами, з’ясовано, що наслідки світового карантину поступово призводять до зростання ролі деглобалізації, а саме регіональної інтеграції та глокації. Визначено вплив воєнних дій в Україні на розвиток деглобалізаційних процесів. Зроблено висновок про важливість аналізу й відображення об’єктивного впливу деглобалізаційних процесів з позицій взаємозв’язку з формуванням економічної політики.
Lo que queda por decir... Compendio de artículos
Authors:   Universidad del Azuay, Ugalde-Vásquez Andrés
Published: February 2023

LO QUE QUEDA POR DECIR... compendio de artículos de Andrés Ugalde Vásquez, se presenta dividido en cinco partes de acuerdo al autor y a la temática de los escritos. Política, Cultura y cotidianidad, Episodios históricos, Biografías y un apartado más específico sobre Cuenca, conforman esta selección que en realidad es un testimonio escrito de lo que piensa , en lo que cree y de los combates intelectuales del autor. Una buena forma de aproximarse a esta selección de artículos de Andrés Ugalde Vásquez es hacerlo desde la triple perspectiva de la literatura, la política y lacátedra. Tres actividades profundamente humanas y solidarias, pues se las practica pensando más en los demás que en uno mismo. 326 páginas ISBN: 978 - 9942 - 847 - 28 - 7 e-ISBN: 978 - 9942 - 847 - 29 - 4
Математична модель опису фону автомобільних транспортних засобів, що функціонують у контрольованій зоні біля стратегічного об’єкта
Authors: Azarenko Olena , Honcharenko Yulia , Divizinyuk Mykhailo , Mirnenko Volodymyr , Lukashenko Victoria
Published: February 2023

Мета роботи: розробка математичної моделі опису фону автомобільних транспортних засобів, що функціонують у контрольованій зоні біля стратегічного об’єкта.

Метод дослідження: дослідження здійснювалися з використанням методів систем масового обслуговування та функціональ-ного аналізу, системного аналізу та математичного моделювання, теорії систем та теорії автоматизованого управління.

Результати дослідження: математична модель опису фону автомобільних транспортних засобів, що функціонують у контрольованій зоні біля стратегічного об’єкта.

Теоретична цінність дослідження: уточнено визначення ситуаційного фону автомобільних транспортних засобів та класифікацію порушень використання автомобільних транспортних засобів; розроблено математичну модель, яка описує ситуаційний фон автомобільних транспортних засобів.

Тип статті: функціонально-синтезуючий, що описує нову модель динамічного процесу.
Regional integrated assessment of climate change impact on cotton production in a semi-arid environment
Authors: Ahmad S , Ahmad I , Ahmad B , Ahmad A , Wajid A , Khaliq T , Abbas G , Wilkerson CJ , Hoogenboom G
Published: February 2023

Climate change has a negative impact on the productivity of agricultural crops at local, regional and global levels. Foodstuff security and sustainable livelihood of cotton farmers in the core cotton growing region in Punjab, Pakistan is under threat because of decreased yield due to climate change. The quantification of the integrated impact assessment of climate change for developing adaptation approaches for cotton is vital for improving productivity at a regional level and improving food security at a national level. Two crop models were evaluated with on-farm survey data of 165 farms employing stratified random sampling techniques. Representative agricultural pathways (RAPs) were developed for characterizing future cotton production. Global climate models (GCMs) depicted a rise of 3.6 and 4.3°C for maximum and minimum temperature, respectively, along with a decreased in rainfall of 600 mm under Representative Concentration Pathway (RCP) 8.5. The expected temperature rise for the hot-dry climate would cause a reduction in productivity of 35.3 and 39.2% by mid-century for RCP4.5 and RCP8.5, respectively, according to the Decision Support System for Agrotechnology Transfer (DSSAT) model, while the Agricultural Production System Simulator (APSIM) showed a reduction of 51.1 and 59.6%, respectively. Increases under the current adaptation of a 15% increase in each of nitrogen and planting density ranged from 1.1 to 6.3% for DSSAT and 2.6 to 8.2% for APSIM. Climate-adapted cotton productivity was projected to rise from 18.7 to 35.9% for DSSAT and from 13.8 to 42% for APSIM for all GCMs. Results showed that current and future cotton systems are adversely impacted by climate change; however, climate-change-adapted management approaches could offset possible reductions in productivity. Sustained cotton productivity in the core cotton zone requires capacity building amongst farmers, enabling them to improve their crop management in the face of seasonal climate variability and future climate change.
DEVELOPMENT OF AN AUTOMATED INFORMATION SYSTEM FOR CALCULATING THE MOVEMENT OF A HIGH-SPEED SMALL-SIZED BODY
Authors:   St. Petersburg University of the Ministry of Internal Affairs of Russia, St. Petersburg, Russian Federation, SHALAGINOVA OLGA , STAKHNO ROMAN , GONCHAR ARTEM
Published: February 2023

The article presents a variant of the development of an automated information system for mathematical modeling of the movement of a high-speed small-sized body based on differential equations and approximation of the trajectory of a high-speed small-sized body by numerical methods, as well as a comparative analysis of various options for numerical solutions. The automated information system allows calculating the flight trajectory coordinates of a high-speed small-sized body based on a differential equation, as well as determining the flight trajectory coordinates by the Euler method, using the Newton interpolation polynomial and the Lagrange interpolation polynomial. In the article, a search for a suitable variant of numerical solutions is carried out, as well as calculations of the movement of a high-speed small-sized body under conditions of limited time for decision-making. The substantiation of the use of an automated information system to automate the calculation and analysis of the movement of a high-speed small-sized body is carried out. While designing an automated information system for calculating and analyzing the flight of a high-speed small-sized body, it is proposed to apply four modules for calculating the flight trajectory of a high-speed small-sized body by numerical methods and a module for comparative analysis and making the results of the optimal variant. The proposed automated information system should provide users with uninterrupted operation, a convenient interface, the required system response time to a request, and the creation of necessary reports. The reports should reflect all types of calculations, as well as a comparative analysis with the choice of the optimal option for calculating the flight path of a high-speed small-sized body. An automated information system is needed to improve the quality of calculations and analysis of movement in the development of new and modernization of existing small arms.
MATH METHODS AND MODELS OF PRODUCTS KNOWLEDGE MANAGEMENT
Authors:   Financial University under the Government of the Russian Federation, Moscow, Russian Federation, TRISHIN ALEXEY
Published: February 2023

The purpose of this research work is to review the existing literature on methods and solutions to the problem of efficient storage and processing of semi-structured semantic information, including in the field of product knowledge management. At the beginning of the article, the rationale for the relevance of the study is given, then it discusses possible ways to build an ontology of semantic networks, various types of knowledge representation, a stack of possible technologies on which such networks can potentially be implemented. An explanation of the semantics, ways to search for information in such systems, including an overview of the semantic data query languages used, as well as ready-made implementations of knowledge bases, is given. The result of the research work was the creation of an extensive database of analyzed sources, which raises the problem of processing semi-structured heterogeneous data, as well as searching for information on them. In addition, as a result of the study, the most effective solution to the above problem was derived - the construction of an ontology of knowledge, the representation of knowledge within the ontology, semantic networks and their architecture, and implementation. Finally, the author managed to prove a high degree of relevance of further qualitative and in-depth scientific research on the problem considered in the research work.
USING A CERAMIC INSERT WITH A BANDAGE IN THE AIR TUYERE OF A BLAST FURNACE
Authors:   National University of Science and Technology “MISIS”, Moscow, Russian Federation, GOLOSHAPOV KIRILL , KOBELEV OLEG ,   Central Research Institute for Mechanical Engineering Technology, Moscow, Russian Federation, TITLYANOV ALEKSANDR , GERASIMOVA ALLA
Published: February 2023

The supply of natural gas to the tuyere for the hot blast of the blast furnace, carried out in order to save coke, leads to an increase in heat losses through the walls of the tuyere channel and a decrease in its service life. To reduce heat losses and increase the service life of the tuyere, thermal insulation inserts are used in the channel for blowing - they reduce heat losses through the channel walls, but are prone to destruction under the influence of thermal stresses. The paper considers an increase in the durability and thermal insulation ability of a ceramic insert into a channel for supplying hot blast due to the installation of a ceramic bandage in the form of a ring in it. In the Ansys environment, the processes occurring in the blast channel of a blast furnace truck with a ceramic insert with a bandage installed in this channel were simulated. It is established that a greater completeness of the gorenje reaction and an increase in the temperature of the hot blast is achieved by using a ceramic bandage. The minimum values of stresses and deformations are achieved in the design variant in which the bandage closes the cavity between the insert and the flange. At the same time, the values of temperatures, stresses and deformations in the bandage are less than in the insert itself.
SOFTWARE AND HARDWARE COMPLEX FOR INVESTIGATION OF TECHNICAL CHANNELS OF INFORMATION LEAKAGE BASED ON HIGH-FREQUENCY IRRADIATION METHOD
Authors:   National Research University of Electronic Technology, Moscow, Russian Federation, PORKHUN ANATOLY , DUSHKIN ALEXANDER ,   MIREA - Russian Technological University, Zelenograd, Russian Federation, MESHCHERYAKOV ROMAN ,   Institute of Control Problems named after V.A. Trapeznikov RAS, Moscow, Russian Federation, SAVCHENKO YURY ,   Institute of Microdevices and Control Systems named after L.N. Presnukhina of the National Research University of Electronic Technology, Moscow, Russian Federation, SHCHERBAKOV VITALY
Published: February 2023

The option of creating an information leakage channel using high-frequency radiation (for example, auxiliary technical means or semi-active stowage devices installed indoors) is one of the active methods for obtaining acoustic speech information. This paper provides a rationale for the requirements for technical characteristics and the scheme for constructing a device for detecting high-frequency radiation signals. It serves to develop a software and hardware complex for the study of technical channels of information leakage, based on the method of high-frequency irradiation. The ultimate goal is to create a prototype of a means for detecting and suppressing receiving devices of high-frequency irradiation equipment based on software-defined devices. The paper describes an approach to the creation of the hardware and software parts of the complex, presents the results of studies on the detection of signals in a wide frequency range.
Punctuated equilibrium and the dynamics of political participation: the case of letter writing
Authors: Casey Daniel
Published: February 2023

While research has shown that policy outputs are punctuated, there is a paucity of research about the punctuation of public opinion and political participation. Policymakers rely on political participation to understand public opinion, so it is important to understand the patterns and flows of political participation, to help understanding democratic responsiveness, and how policy outputs behave. I advance punctuated equilibrium theory by applying it to individuals' decision to participate. I argue that bounded rationality and disproportionate information processing, will result in a punctuated equilibrium pattern. Using innovative new datasets on the volume and topic of letters to the Australian Prime Minister and American President, I find consistent evidence of punctuations, using weekly, fortnightly, and annual data, across both Australia and the USA. These results extend punctuated equilibrium further up the policy process chain than has previously been done, supporting its claim to be a full theory of government information processing.
Ionic-liquid-based approaches to improve biopharmaceuticals downstream processing and formulation
Authors: Almeida Catarina , Pedro Augusto Q. , Tavares Ana P. M. , Neves Márcia C. , Freire Mara G.
Published: February 2023

The emergence of biopharmaceuticals, including proteins, nucleic acids, peptides, and vaccines, revolutionized the medical field, contributing to significant advances in the prophylaxis and treatment of chronic and life-threatening diseases. However, biopharmaceuticals manufacturing involves a set of complex upstream and downstream processes, which considerably impact their cost. In particular, despite the efforts made in the last decades to improve the existing technologies, downstream processing still accounts for more than 80% of the total biopharmaceutical production cost. On the other hand, the formulation of biological products must ensure they maintain their therapeutic performance and long-term stability, while preserving their physical and chemical structure. Ionic-liquid (IL)-based approaches arose as a promise alternative, showing the potential to be used in downstream processing to provide increased purity and recovery yield, as well as excipients for the development of stable biopharmaceutical formulations. This manuscript reviews the most important progress achieved in both fields. The work developed is critically discussed and complemented with a SWOT analysis.
Portable paper-based electrochemiluminescence test incorporating lateral-flow immunosensors for detection of interferon-γ levels
Authors: Yuan Shichao , Xie Guihua , Yang Xiang , Chen Yu , Zhang Hongbin
Published: February 2023

Tuberculosis (TB) poses a serious threat to human health and social development. Accurate diagnosis of mycobacterium tuberculosis infection plays a critical role in the prevention and treatment of tuberculosis. Interferon-γ (INF-γ) release assay (IGRA) is currently the only quantitative tuberculosis infection diagnosis method. An accurate, fast, and easily handled INF-γ detection method is the key to obtaining accurate results. Herein, we report a novel paper-based electrochemiluminescence (ECL) method based on lateral flow immunosensors that combines the easy handling characteristics of immunochromatography and the high sensitivity of electrochemiluminescence to detect IFN-γ. To our knowledge this is the first INF-γ detection method that combines immunochromatography with electrochemiluminescence. The paper-based ECL-LFI test consists of a sample pad, conjugation pad (with binding antibody IFN-γ-Ab1 conjugated with ruthenium tripyridine), detection pad (with capture antibody IFN-γ-Ab2 immobilized on nanospheres), absorbent pad, and electrode for signal activation. The ECL signal is obtained by cyclic voltammetry scanning at a speed of 0.1 V/s in the detection area of the paper-based ECL-LFI test. In our experiments, the paper-based ECL-LFI test exhibited a minimum detection limit of 2.57 pg/mL within 12 min, and a broad detection range of 2.57–5,000 pg/mL, with repeatability of 8.10% and stability of 4.97%. With the advantage of high accuracy and sensitivity, easy handling, and low user training requirements, this ECL-LFI test might be used as point-of-care testing (POCT) in the IGRA for tuberculosis diagnosis.
Towards early detection of neurodegenerative diseases: A gut feeling
Authors: Makdissi Stephanie , Parsons Brendon D. , Di Cara Francesca
Published: February 2023

The gastrointestinal tract communicates with the nervous system through a bidirectional network of signaling pathways called the gut-brain axis, which consists of multiple connections, including the enteric nervous system, the vagus nerve, the immune system, endocrine signals, the microbiota, and its metabolites. Alteration of communications in the gut-brain axis is emerging as an overlooked cause of neuroinflammation. Neuroinflammation is a common feature of the pathogenic mechanisms involved in various neurodegenerative diseases (NDs) that are incurable and debilitating conditions resulting in progressive degeneration and death of neurons, such as in Alzheimer and Parkinson diseases. NDs are a leading cause of global death and disability, and the incidences are expected to increase in the following decades if prevention strategies and successful treatment remain elusive. To date, the etiology of NDs is unclear due to the complexity of the mechanisms of diseases involving genetic and environmental factors, including diet and microbiota. Emerging evidence suggests that changes in diet, alteration of the microbiota, and deregulation of metabolism in the intestinal epithelium influence the inflammatory status of the neurons linked to disease insurgence and progression. This review will describe the leading players of the so-called diet-microbiota-gut-brain (DMGB) axis in the context of NDs. We will report recent findings from studies in model organisms such as rodents and fruit flies that support the role of diets, commensals, and intestinal epithelial functions as an overlooked primary regulator of brain health. We will finish discussing the pivotal role of metabolisms of cellular organelles such as mitochondria and peroxisomes in maintaining the DMGB axis and how alteration of the latter can be used as early disease makers and novel therapeutic targets.
miR-514a promotes neuronal development in human iPSC-derived neurons
Authors: Akaba Yuichi , Takahashi Satoru , Suzuki Keiichiro , Kosaki Kenjiro , Tsujimura Keita
Published: February 2023

Proper development and function of the central nervous system require precise regulation of gene expression. MicroRNAs (miRNAs), a group of small non-coding RNAs that can negatively regulate gene expression at the post-transcriptional level, are critical regulators of neuronal development, and dysregulation of microRNAs has been implicated in various neurological disorders. Changes in microRNA expression and repertoire are related to the emergence of social and behavioral variations in closely related primates, including humans, during evolution. MicroRNA-514a (miR-514a) is an X-linked miRNA that is conserved in species with higher social and cognitive functions, and frequent tandem duplications of miR-514a have been found in primate genomes. Here, we demonstrate that miR-514a plays a crucial role in neuronal development in neurons derived from human induced pluripotent stem cells (iPSCs). Overexpression of miR-514a increased dendritic length, soma size, and activity levels of mammalian target of rapamycin (mTOR) signaling in induced pluripotent stem cell-derived neurons, whereas blocking of endogenous miR-514a inhibited neuronal development. Furthermore, we performed a functional analysis of the miR-514a variation found during primate evolution, to investigate the impact of miR-514a sequence variation and associated changes in expression on brain development during evolution. We found that mutation in miR-514a significantly reduced the expression of the mature form and abolished the effects observed when native miR-514a was expressed. Our findings provide new insights into the functional role of miR-514a in the regulation of neuronal development and evolution of primate brain development.