bluuebunny/crossref_metadata_2025 huggingface dataset:
KAJIAN KONSEP EKOLOGIS PADA GEDUNG PERPUSTAKAAN PUSAT UGM
Authors: Adi Alifiano Rezka
Published: June 2020

Title: The Study of Ecological Concept in the Central Library of Gadjah Mada University

Ecological architecture becomes one of the concept as well as solutions in the building design which minimizes environmental damages and maintains the quality of human life. The central library of Gadjah Mada University in Yogyakarta is used as the research object to rate its ecological level. This study uses a quantitative method to rate its ecological level based on the ecological design principles of Sim Van der Ryn such as ecological accounting, design with nature, and making nature visible. The assessment parameters are based on some references such as the greenship of GBCI, the principles of tropical architecture, and the principle of building accessibility. The results showed that generally, the library has applied ecological concept well through some strategies such as extensive greening, energy efficiency, adequate natural lighting, slim building masses, shading elements, and some facilities for the difable. Some measurements are done to find out the ecological performance of the building such as energy efficiency by 39.17%; daylighting 300 lux at 60.67% of indoor area, visualization of solar radiation reception, and OTTV value by 19,85 watt/m2. However, there are some necessary evaluations such as leakage on the ceiling or the application of greenroof that can be further optimized.
Oleamide in Ipomoea and Dillenia Species and Inflammatory Activity Investigated through Ion Channel Inhibition
Authors: Ameamsri Unchaleeporn , Chaveerach Arunrat , Sudmoon Runglawan , Tanee Tawatchai , Peigneur Steve , Tytgat Jan
Published: June 2020

Background:

Oleamide is an essential substance for human health. So, the plants with high
oleamide content are great sources for health care products.

Objective:

This study is conducted to investigate the quality of oleamide in plants and test the bioactivity
in the selected two studied species.

Methods:

The three Ipomoea and five Dillenia species including Ipomoea alba, Ipomoea aquatica and
Ipomoea pes-caprae, and Dillenia indica, Dillenia obovata, Dillenia ovata, Dillenia parviflora and
Dillenia pentagyna were investigated for the quantity of oleamide by high-performance liquid chromatography.
The biological activity test was conducted on the powder formulation of the chosen plants,
Dillenia ovata and Dillenia parviflora at a ratio of 30:70, for anti-inflammatory activity ex vivo on a
panel of molecular targets through ion channel inhibition including voltage-gated sodium channel,
voltage-gated potassium channel, and the cardiac ion as human ether-a-go-go related gene.

Results:

The results showed that the leaf extracts of I. aquatica and D. ovata gave the highest and subsequent
oleamide quantity i.e. 7.52 and 5.17 mg/g, respectively. Out of the Dillenia formulation which
contained various compounds, oleamide showed the highest percentages of inhibition at 8.0-20.0%,
and 6.2-14.2% in voltage-gated sodium channel, and voltage-gated potassium channel which had
slightly lower values than the oleamide standard, and no effect as 0.0% value inhibition in the cardiac
ion channel.

Conclusion:

The Dillenia formulation exhibits anti-inflammatory activity without affecting the heart.
Accordingly, the three studied Ipomoea and three studied Dillenia species may be used for the same
activity as a single component or formulation with effective solvent for disease treatments.
Nanoparticle Based Gene Therapy Approach: A Pioneering Rebellion in the Management of Psychiatric Disorders
Authors: Rehman Saleha , Nabi Bushra , Pottoo Faheem Hyder , Baboota Sanjula , Ali Javed
Published: June 2020

:

The neuropsychiatric illnesses have been enigmatic, with no effective treatment to date.
The complexity and heterogeneity of psychiatric disorders are daunting for the development of novel
treatment modalities. The conventional treatment approaches are less effective and are associated with
several side effects, thus creating the need for the development of more innovative strategies. Since
psychiatric disorders are known to exhibit genetic linkage, gene therapy has created an interest among
the researchers worldwide. The delivery of nucleic acids is a complex process requiring the transport
of genetic material across various intracellular and extracellular barriers to reach the target cells
eliciting the transfection process. Therefore, the identification or development of the delivery system
for nucleic acid delivery still remains the challenge. Viral vectors are quite effective but are associated
with toxicity and side effects. With the rapid advancement in the field of nanotechnology, nanosized
materials were identified to be the perfect candidate for nonviral vectors in gene delivery. The biggest
advantage of nanoparticles is that their surface can be engineered in many possible ways to deliver the
drugs directly to the target site. Although gene therapy has already been established as an innovative
treatment modality for several neurological diseases, its use in psychiatry still warrants more
investigations for its translation into clinical use. The present manuscript discusses the prospects of
gene therapy in psychiatric disorders, their benefits, and pitfalls. The review embarks upon the
importance of nanoparticle-based gene therapy for effective management of psychiatric disorders.
Can the Lewis Basicity of an Isolated Solvent Molecule be Used for Characterizing Solvent Effects?
Authors: Gal Jean-François , Maria Pierre-Charles
Published: June 2020

Background:

The ubiquitous Lewis acid/base interactions are important in solution processes.
Analytical chemistry may benefit from a better understanding of the role of Lewis basicity at
the molecular level or acting through a bulk solvent effect.

Objective:

To delineate (i) the basicity at a molecular level, hereafter referred to as solute basicity,
and (ii) the solvent basicity, which is a bulk-liquid property.

Methods:

The literature that relates Lewis basicity scales and solvent effects is analyzed. A special
focus is placed on two extensive scales, the Donor Number, DN, and the BF3 Affinity scale, BF3A,
which were obtained by calorimetric measurements on molecules as solutes diluted in a quasi-inert
solvent, and therefore define a molecular Lewis basicity. We discuss the validity of these solute
scales when regarded as solvent scales, in particular when the basicity of strongly associated liquids
is concerned.

Results:

We demonstrate the drawbacks of confusing the Lewis basicity of a solvent molecule, isolated
as a solute, and that of the bulk liquid solvent itself.

Conclusion:

Consequently, we recommend a reasoned use of the concept of Lewis basicity taking
clearly into account the specificity of the process for which a Lewis basicity effect may be invoked.
In particular, the action of the Lewis base, either as an isolated entity or as a bulk liquid, must be distinguished.
Nanoparticles and Significance of Photocatalytic Nanoparticles in Wastewater Treatment: A Review
Authors: Sagir Muhammad , Tahir Muhammad B. , Akram Jehangir , Tahir Muhammad S. , Waheed Usama
Published: June 2020

Background:

In the present situation where there is a water shortage globally, nanoparticles
can play a vital role in treating wastewater to make it usable for several processes. Industrial
wastewater contains numerous heavy metals and associated wastes that enter our food chain by one
means or other. This article provides a review of applications of nanoparticles in wastewater treatment
and highlights the significance of photocatalytic nanoparticles in general.

Methods:

Online journals and books related to wastewater treatment using nanoparticles are reviewed
to compile their essentials findings. General mechanisms, applications, limitations, and comparison
of photocatalytic nanoparticles are reviewed as well.

Results:

A study of photocatalytic nanoparticles shows that TiO2 and ZnO nanoparticles have excellent
photocatalytic capabilities as compared to other nanoparticles due to their bandgap properties;
however, the usage of these nanoparticles is limited since there is higher recombination rate of electrons
and holes in photocatalysis. Further, individual limitations also exist as TiO2 is inoperable in
the visible light region. So, their heterostructures with other nanoparticles have been developed to
overcome their limitations. Other nanoparticles, like noble metals, and those like CuO, CeO2, SnO2
have potential in carrying out photocatalytic degradation of contaminants of wastewaters.

Conclusion:

Several contaminants can be eliminated from wastewater bodies using photocatalytic
nanoparticles. The efficiency of photocatalytic nanoparticles can be enhanced by coupling them with
suitable species. Research in this area can prevent the water shortage of upcoming years.
Modified Plasma Cytokine Profile in Occupational Dermatitis
Authors: Rascu Alexandra M. , Otelea Marina R. , Mambet Cristina , Handra Claudia , Neagu Ana I. , Rascu Agripina , Giurcaneanu Calin , Diaconu Carmen C.
Published: June 2020

Background:

Despite significant progress in the diagnosis of contact dermatitis, the identification
by specific tests or biomarkers remains an unsolved issue, particularly when needed for the
confirmation of the occupational origin of the disease.

Objective:

To characterize the plasma proteome profile in occupational dermatitis in workers of paint
industry.

Methods:

The study has a case-control design, comparing exposed workers with and without occupational
contact dermatitis, matched for age, gender, occupational history, and comorbidities. An immunological
assay (Human XL Cytokine Array Kit – ARY022B, R&D Systems) was used to measure the
plasma levels of 105 cytokines and chemokines in a pooled sample of the cases and a pooled sample of
the controls.

Results:

A 1.5-fold increase was noticed for interleukin 3, interleukin 10, and leptin in cases, as compared
to controls. Fibroblast growth factor-7 and growth/differentiation factor-15 showed a 1.4-fold
increase, while interleukin 19, interleukin 31, and macrophage inflammatory protein 3 a had only a 1.3-
fold increase. The leukemia inhibitory factor was the only plasma cytokine that showed a 1.3-fold decrease.
All other cytokines had a variation of less than 1.2-fold between cases and controls.

Conclusion:

The recognition of the molecular signatures is very important for an accurate and indisputable
diagnosis of occupational contact dermatitis. In workers from the paint industry, plasma levels
of interleukins 3, 10, 13 and 19, fibroblast growth factor-7, and growth/differentiation factor-15, together
with leukemia inducible factor, may differentiate subjects with contact dermatitis from those
without skin lesions.
Thermo-mechanical Characterization of Insulating Bio-plasters Containing Recycled Volcanic Pyroclasts
Authors: Contrafatto Loredana , Gazzo Salvatore , Purrazzo Antonio , Gagliano Antonio
Published: June 2020

Aim:

The research proposes the reuse of volcanic wastes in the production of lightened and insulating bio-plasters.

Introduction:

The goal is the production of a novel sustainable construction material that reduces the environmental impact.

Methods:

Four mixtures were designed. The recycled Volcanic Ash was used in combination with two bio-compatible binders; basically Natural Hydraulic Lime (NHL) or calcium hydroxide blended with a commercial Portland cement (CH-CEM). To improve thermal properties, CH-CEM mixtures were treated with an Air Entraining Agent (AEA) in two different percentages and a breathable resin (R). The main physical, mechanical and thermal properties were experimentally determined.

Results:

The results of such analysis indicate that the mixture NHL, realized using hydraulic lime as a binder, do not satisfy the threshold of the water absorption coefficient, exceeding the limit established by UNI EN 998-1 standard.

Conclusion:

On the contrary, one of the mixtures CH-CEM, containing both AEA and R, is suitable for use as lightweight plastering mortar and also satisfies the requirements for insulating mortars.
Simultaneous Determination of Telmisartan and Pitavastatin Calcium in Intestinal Perfusate by HPLC: Application to Intestinal Absorption Interaction Study
Authors: Wang Junying , Liu Juan , Song Xiangrong , Fu Chunmei
Published: June 2020

Background:

Hypertension and hypercholesterolemia are two main physiological
risk factors of cardiovascular disease, and commonly occur in combination. Multicompound
combination therapy is rational for the treatment of concurrent hypertension and
hypercholesterolemia, while telmisartan and pitavastatin calcium can be used as a potential
drug combination.

Objective:

The aim of this paper is to study the intestinal absorption and absorption interaction
of telmisartan and pitavastatin calcium.

Methods:

An HPLC method was developed and validated to determine telmisartan and
pitavastatin calcium in intestinal perfusate simultaneously. The in situ single-pass
perfusion in rats was utilized to investigate the effects of concentrations, intestinal segment
(duodenum, jejunum, ileum and colon) and co-administrated drugs on absorption.

Results:

The effective permeability coefficient and the absorption rate constant of telmisartan
were higher in the duodenum as compared to other intestinal segments. However, the
intestinal absorption of pitavastatin calcium was not segmental dependent. The effective
permeability coefficient and absorption rate constant have no significant difference among
three concentrations of telmisartan, pitavastatin calcium individually and their combination.

Conclusion:

The results showed that telmisartan and pitavastatin calcium were transported
passively, and telmisartan and pitavastatin calcium could be absorbed well in all intestinal
segments. The intestinal absorption parameters revealed the absence of any intestinal absorption
interaction when co-administered.

Lay Summary:

Co-administration of telmisartan and pitavastatin calcium can provide a
potential therapeutic strategy for the treatment of concurrent hypertension and hypercholesterolemia.
We are investigating the intestinal interaction of these two drugs in rats using
the developed HPLC method and in situ single-pass perfusion technology. We will calculate
some parameters after administrating two types of drugs either separately or together,
which help reflect changes regarding intestinal absorption and penetration. Compared with
telmisartan and pitavastatin calcium administrated separately, if parameters significantly
change after co-administration, it proves the existence of the intestinal interactions. Moreover,
the results might contribute to clinic drug monitoring.
Plant Stimulant to Nanotoxicity: Recent Advancements and Opportunities
Authors: Verma Nidhi , Sharma Shilpa , Vishwakarma Gajendra Singh , Pandya Alok
Published: June 2020

Nanotechnology has come a long way showing major contributions in the field of agriculture
and food production. The use of nanoparticles (NPs) is increasing day by day as they possess
better solubility, enhanced magnetic and optical properties, and better surface to charge ratio.
The affirmative effects due to the use of NPs have been explained, including enhanced germination,
increased root and shoot length, and the overall increase in plant biomass along with improvement
in physiological parameters like photosynthetic activity. Recently, the toxicological effects of NPs
in agriculture have become a matter of concern. The current review focuses on the generation of reactive
oxygen species (ROS), oxidative damage and defense mechanism in response to phytotoxicity
caused by the use of NPs. The other aspects in this review include the effect of NPs on macromolecule
concentration, plant hormones and crop quality. The review also discusses the future prospects
of NPs on plant phytotoxicity and growth. Furthermore, it also discusses the possible
measures which can be taken for plant protection and growth while using NPs in agriculture.
Withdrawal Notice: The Relationship between Opium Use and Coronavirus Infection: A Brief Research Report from Iran
Authors: Khoshab Hadi , Rajabalipour Mohammadreza
Published: June 2020

The article has been withdrawn at the request of the author of the journal Coronaviruses:

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.
Posterior tracking of multiple target elements
Authors: Moiseev A. A.
Published: June 2020

The posterior method of selecting and tracking the elements (objects) of a group radar target is considered. It allows for estimating the number of elements in a group target and carrying out their preliminary selection. It also helps in evaluating the tracking characteristics of the selected elements. A feature of the method is the preliminary accumulation of a data array to be processed further out of real-time. An histograms analysis is constructed to achieve that based on the processing results of the specified array. The corresponding algorithm provides for variations construction in the spread of the initial moments of the pulses relative to the average value in the packet, as well as modes in the packet and strobe. The decisive function in this case is defined as the product of these variations, and the decisive rule is to find the value of the spacing of the pulse numbers at which the minimum value of the decisive function is achieved. This value is interpreted as the number of elements in the group. The possibility of splitting a group into separate elements using the proposed approach is demonstrated. Mathematical modeling of the tracking procedure allowed comparing two possible methods. The first one is the “strongest neighbor” method, which provides for the choice of the continuation of the pulse with the maximum amplitude in the strobe. The second one is the “nearest neighbor” method, which provides the choice of the continuation of the pulse with the median moment of registration in the strobe. A comparative analysis of these two approaches demonstrated the preference of the “nearest neighbor” method as the one to provide less distortion of the time dependences of the amplitude and frequency. Evaluation of tracking parameters carried out according to the constructed histograms made it also possible to assess the probability of detecting an object during tracking.
Application of digital image processing for autofocusing system construction
Authors: Makarenko A. A. , Vinokurov L. A.
Published: June 2020

The article states the method of autofocusing of the optoelectronic image, based on digital image processing. Some systems of autofocusing which can be used in optoelectronic equipment of unmanned aerial vehicles are considered. The method developed by authors and the program algorithm implementing it are similar to the rules of functioning of an element of the human visual system which executes an estimation of a spectrum of spatial frequencies for the realization of focusing of the image of objects which are of interest or danger and are on different distance from the observer. The best focusing is defined on the greatest width of a spectrum of spatial frequencies of the object. Such estimation allows focusing the necessary object on the observable image even in the absence of binocular vision. The method is based on the numerical analysis of a two-dimensional amplitude spectrum of the image. Results of operation of the stated method which confirm its efficiency are presented.
Methods and tools for radio frequency locators parameters verification
Authors: Ibragimova Ya. G. , Tereshenkova O. A. , Kim A. A. , Luginya V. S.
Published: June 2020

Radio frequency locators, or radars, are one of the most common and effective devices of remote sensing of the atmosphere which are used to detect and recognize distant objects, measure their dynamic parameters, or research the properties of the atmosphere. The methods and tools for verifying their operational parameters are of great interest, since the specificity of the radar in most cases makes it difficult to verify them due to the impossibility of creating a reference atmospheric path. To date, there is no single methodology for assessing the control of the basic operational parameters of radars. The methods and technical tools used are often difficult to implement, have a narrow range of applications and require confirmation of their own characteristics. The article presents the classification and analysis results of existing methods and technical tools of radio frequency locators operational parameters verification. Based on the analysis, recommendations for choosing an approach to conducting verification measures depending on the type of radar are given.
Research of results in problem of choice in the process of alteration of experts’ values
Authors: Pryadko S. A. , Kuksova O. S. , Ivanov A. E.
Published: June 2020

The current article highlights one of the problems of the well-known analytic hierarchy process, which is the necessity to estimate values of ultimate evaluations (absolute priorities) in the process of alteration of preliminary evaluations (relative priorities). As this method is widely used in many areas, where problems of choice with criteria appear and cannot be described in figures, the problem is relevant. The method is described briefly. The approach is put down, which allows taking the alteration of evaluations into account. The approach is based on logical sorting out of varieties of allowed alterations with adding calculations in the table. Permutation of the elements, as well as decomposition of number into sum of numbers, are used during enumeration. It is easy to implement both procedures using Python. The table can be imported into a database for further research by creating the SQL queries. Research results can help in the event of a dispute and to forecast future evaluations.
Urban health and happiness in hutongs and highrises
Authors: Sass Hans-Martin
Published: June 2020

Urban bodies are complex integrated adjustable systems (CIAS), in flexible interaction with their natural, cultural, economic and political biotopes. Small entangled communities such as hutongs, existing in China for over 1000 years, and modern high-rise apartment buildings to a different extent represent more or less healthy and stable communities, based on interpersonal and interfamilial interaction, trust and solidarity, shared interest and involvement in sports, arts, gardening, social and other activities. Urban and other communities are interconnected by common history, narratives and visions, religions and internet cyberspaces. Religions and new internet communities extend beyond the local communities of hutongs, apartment buildings, cities and businesses; they may support or threaten local urban community and coherence.
Evaluation of a Text Messaging Intervention to Support Self-Management of Diabetes During Pregnancy Among Low-Income, Minority Women: Qualitative Study
Authors: Yee Lynn , Taylor Shaneah , Young Maria , Williams Makayla , Niznik Charlotte , Simon Melissa
Published: June 2020

Background

Given the growing burden of diabetes in underserved communities and the complexity of diabetes self-management during pregnancy, the development of interventions to support low-income pregnant women with diabetes is urgently needed.

Objective

This study aims to develop and pilot test a theory-driven curriculum of SMS text messaging for diabetes support and education during pregnancy.

Methods

This was a prospective pilot investigation of a novel SMS text messaging intervention offered to pregnant women with pregestational or gestational diabetes mellitus and publicly funded prenatal care. Prior work yielded a conceptual model of diabetes self-management barriers and support factors in this population, which was used to guide curriculum development along with health behavior theories. Participants received three supportive or educational one-way text messages per week during pregnancy. In-depth semistructured interviews were performed at study exit to solicit feedback on the program. Narrative data were analyzed using the constant comparative technique to identify themes and subthemes.

Results

Participants (N=31 enrolled and n=26 completed both interviews) consistently reported that SMS text messaging provided enhanced motivation for diabetes self-care, reduced diabetes-related social isolation, increased perceived diabetes-associated knowledge, enhanced comfort with the health care team, and reduced logistical burdens of diabetes during pregnancy. Participants requested enhanced interactive and customizable features in future intervention iterations.

Conclusions

Pregnant women with diabetes who were enrolled in this pilot study of an SMS text messaging curriculum for diabetes support described enhanced motivation, knowledge, and comfort with diabetes self-care activities as a result of the health education intervention. The next steps include enriching the interactive features of the intervention and investigating the effect of the intervention on perinatal outcomes.
The Impact of a Smartphone App on the Quality of Pediatric Colonoscopy Preparations: Randomized Controlled Trial
Authors: Brief James , Chawla Anupama , Lerner Diana , Vitola Bernadette , Woroniecki Robert , Morganstern Jeffrey
Published: June 2020

Background

Smartphone apps have been successfully used to help adults prepare for colonoscopies. However, no study to date has investigated the effect of a smartphone app on pediatric colonoscopy preparation.

Objective

The aim of this study is to determine if an app (SB Colonoscopy Prep) designed to educate and guide patients through their colonoscopy preparation will yield benefits over paper-based instructions and information.

Methods

In total, 46 patients aged 5-18 years received either app-based or written material with instructions on how to take their prep medications as well as information about the colonoscopy procedure. Prep quality, the number of calls to the gastroenterology service, and patient arrival time were recorded. After the procedure, a questionnaire was given to each patient through which they graded their knowledge of the procedure both before and after receiving the app or written material.

Results

App users had higher mean Boston scores versus control subjects receiving written instructions (7.2 vs 5.9, P=.02), indicating better colonoscopy preps. In total, 75% (15/20) of app users and 41% (9/22) of written instruction users had preps categorized as “excellent” on the Boston scale. We found no significant differences in knowledge about the procedure (app users: 10/20 [50%], written instruction users 8/22 [36%]; P=.37), phone calls to the gastroenterology clinic (n=6 vs n=2; P=.27), or arrival times at the endoscopy suite (44 min vs 46 min before the scheduled procedure time; P=.56).

Conclusions

Smartphone app use was associated with an increased number of colonoscopy preps classified as “excellent” on the Boston scale. There was no significant difference between app users and the control group regarding the number of calls to the gastroenterology clinic, patient arrival time, or patient knowledge about the procedure.

Trial Registration

ClinicalTrials.gov NCT04590105; https://clinicaltrials.gov/ct2/show/NCT04590105
The Effect of Objectively Collected Medication Adherence Information on Bipolar I and Major Depressive Disorder Treatment Decisions: A Randomized Case Vignette Study of Psychiatric Clinicians (Preprint)
Authors: Ruetsch Charles , Liberman Joshua , Clerie Jennifer , Davis Tigwa , Sajatovic Martha , Velligan Dawn I. , Forma Felicia M.
Published: June 2020

BACKGROUND

Adherence to antipsychotic medications is critical for treatment and relapse prevention in serious mental illness. Accurate assessment of medication adherence can be difficult, and clinicians frequently overestimate patient adherence. Newly available digital medicine technologies can objectively assess patient medication adherence and share the data with clinicians.

OBJECTIVE

To estimate the influence of objectively collected antipsychotic medication adherence information on clinician treatment decisions among patients with bipolar (BD) and major depressive (MDD) disorders.

METHODS

This study was a cross-sectional two-group random assignment survey of psychiatric clinicians who prescribe antipsychotic medication in the treatment of BD and/or MDD. Clinicians (N=180) were recruited using national association lists. Respondents were presented with five simulated patient case summaries (vignettes) each presenting descriptions of symptoms, level of functioning, and self-reported medication adherence. Clinicians were presented with either BD or MDD vignettes and were randomly assigned to vignettes that presented subjective (self-report) or objective adherence information. For each vignette, respondents were asked to recommend adjustments in medication.

RESULTS

A total of 180 clinicians participated. Those who were asked to make decision on care of BD (N=90) were more likely to modify antipsychotic treatment as opposed to mood stabilizers. Clinicians who were asked to make care decision of MDD patients (N=90) were more likely to modify antidepressant treatment as opposed to antipsychotic prescriptions. Among vignettes indicating non-adherence, reports derived from objective adherence data increased recommendations to adopt long-acting injectable antipsychotics though the rate of LAI choice overall was greater for BD vs. MDD.

CONCLUSIONS

Objective adherence data helps clinicians distinguish between medication non-adherence and medication non-response, thus allowing them to make more informed treatment decisions. These data suggest that the presence of objective adherence data will influence clinicians’ prescribing patterns as illustrated by their recommendations to modify antipsychotic medication prescriptions for patients with BD and to a lesser degree those with MDD.
An experimental study of a forced ventilation pile
Authors: Okorokov Nikita S. , Korkishko Alexandr N. , Korzhikova Anastаsiya P.
Published: June 2020

Introduction. Thermal stabilization of foundation soils is a most widely spread method of engineering protection of structures in the cryolithic zone. Presently, as a rule, any construction is feasible if the footing temperature remains negative in the regions that have permafrost soils. In the article, the co-authors have analyzed a conceptually new method of thermal stabilization of soil, that is, the application of forced ventilation piles. The goal of the laboratory experiments is to simulate the frozen soil behaviour in case of its exposure to a ventilated and cooled pile. The co-authors have solved the problem of soil temperature reduction to ensure the soil transition from the thawed state into the frozen or plastic frozen state. Besides, the co-authors have substantiated the efficiency of this thermal stabilization method. The subject of this research is a ventilated pile, driven into sandy soil and ventilated by the cool air generated by the refrigerating unit.

Materials and methods. A laboratory study of a scaled model.

Results. According to the data provided by the temperature sensors, a forced ventilation pile kept the soil frozen in the radius of 10 cm as of the end of the second winter, which means 2 meters, given the scale factor of the experiment. This methodology can also be applied as a method of thermal stabilization and refrigeration of soils. In the course of the experiment, thawed soil froze. In summer, the seasonal active soil layer thawed, and negative temperatures remained unchanged and generated a frost table registered by the temperature fields, used in the summer period.

Conclusions. Soil remains frozen in summer; the bearing capacity of the pile remains unchanged.

Acknowledgements: The co-authors would like to express thanks to the Central research and development laboratory of permafrost research of the Federal State Budgetary Educational Institution of Higher Education Tyumen Industrial University, and to anonymous reviewers.
A research into the distribution of silicium dioxide nanoparticles in the mixing water
Authors: Nemuschenko Dmitry A. , Larichkin Vladimir V. , Onipchenko Anastasiya P. , Subbotin Vasilij S.
Published: June 2020

Introduction. The co-authors studied suspensions of silicium dioxide nanoparticles in the water. The application of suspensions helps to most effectively add nanoparticles to slip ceramic mixtures and mixtures that contain concrete. A review of publications has proven that Russian and foreign researchers are willing to learn more about nanoparticles used to modify various materials. Particles having different chemical properties are applied depending on the types of problems to be solved. The method of ultrasonic dispersion of fillers in the matrix material is widely used; surfactants stabilize suspensions and mortars. Silicon dioxide, being one of the cheapest ultra-dispersed powders, has been proven as an active filler designated for building materials.

Materials and methods. A method of ultrasonic dispersion was used to uniformly distribute nanoparticles in the water. A surfactant was added to the suspension to reduce the reaggregation of particles and to rise the stability of suspensions in the course of time. The turbidimetric method was employed to control the nanoparticle distribution efficiency in the suspension, and a spectrophotometer was used to identify the dimensions of solid particles by measuring the optical density.

Results. The co-authors have proven the efficiency of the ultrasonic method in distributing nano-sized particles over the water. The suspensions, developed by the co-authors, were used to mold samples of ceramics; a scanning electron microscope and a nozzle, designated for the identification of chemical compositions, were used to identify dimensions of nanoparticle conglomerates in the matrix. The co-authors identified the concentration of OP-10 surfactant that was optimal for the destruction of conglomerates in the suspension; the impact of the ultrasonic treatment duration was assessed in respect of the suspension.

Conclusions. The research findings can be contributed to ceramic production technologies for versatile nanoparticles to be employed to modify materials.
On estimating the amount of fuel and energy consumable in the process of mechanized work performance within the framework of low-rise construction
Authors: Korol’ Elena A. , Zhuravleva Аnastasia A.
Published: June 2020

Introduction. Low-rise housing construction is an area that has extensive potential in Russia. One of the top-priority objectives, pursued by public politicians in the Russian Federation, is to improve the energy efficiency of versatile branches of the national economy. Given the fact that the building construction, representing a comparatively short stage in the building’s life cycle, is energy consuming, energy saving in the process of construction turns particularly relevant. Prevailing manual labour and low-capacity construction machinery substantially reduce power consumption at the stage of low-rise housing construction. Widely spread low-rise construction technologies and consequent discrepancies in structural and technological solutions determine the mode of operation, numbers and the engineering performance of construction machines. Hence, energy resources, to be consumed in the process of mechanized work performance on a construction site, is projected, and these projections may differ. As for the rational expenditure of resources, consumption of fuel and energy can be expediently planned at the stage of construction project scheduling.

Materials and methods. The co-authors have analyzed scientific publications focused on the subject of research, applied organizational and construction process patterns developed in the form of work performance schedules needed to regulate fuel consumption in the process of mechanized work performance, whenever low-rise construction technologies are used.

Results. The co-authors offer a set of instruments, designated for the calculation of fuel consumption in the process of mechanized work performance, whenever low-rise construction technologies are used.

Conclusions. At the project planning stage, the fuel consumption rate analysis, applicable to construction machines and mechanisms, enables to (1) project the amount of fuel consumed in the course of specific construction works performed within the framework of the whole process of construction, (2) to identify technologies and mechanized units which are most rational in terms of power consumption.
Transformation features in rural settlement system of belarus
Authors: Gorbenkova Elena V.
Published: June 2020

Introduction. The sustainability of the rural settlement is a key land use planning objective in the present-day socio-economic environment. This issue is particularly relevant Belarus as the most urbanized country of the European region. The retrospective analysis is the most effective tool for studying the transformational processes underway in the settlement system. The mission of this article is to study the transformation of the rural settlement pattern in Belarus.

Materials and methods. The research methodology encompasses general scientific methods (a system approach, a retrospective analysis) and special transdisciplinary methods (cartographic modeling backed by GIS tools). Population census data, open-access cartographic sources and land-use planning documents were studied, as well.

Results. Three periods were identified in the history of rural settlement in Belarus: pre-revolutionary (1897–1917), Soviet (1917–1991) and contemporary ones (1991–present). Within these periods, transformational processes were particularly active. A retrospective analysis of the structure and spatial organization of rural settlement processes was performed for each period. Special features of the Belarus rural settlement structure were highlighted. They include polarization, growing population shares and sizes of major rural populated areas, the “drain” of large and medium-sized populated areas, and the degradation of small ones.

Conclusions. The retrospective analysis enabled the author to identify the most significant historical periods in the history of rural settlement. Any settlement transformation was mainly driven by social and political factors. By summarizing the findings, the author identified two patterns of transformation applicable to rural settlement patterns: development and degradation. Three types of spatial reorganization of rural populated areas were formulated: relocation to the city, relocation to rural populated areas, or settlement system centres, and relocation to ordinary rural populated areas. Further research undertakings will focus on conceptualizing the spatial organization model of the rural settlement system.
Formulation and Evaluation of Pulsatile Drug Delivery System of Zafirlukast
Authors: Madhavi Ala Vijaya , Brahma Reddy D Rama , Venugopal M , Srihari N , Chenniah P , Koteswarao P
Published: June 2020

In the current scenario of pharmaceutical research much attention has been focused on patients health in terms of therapeutic efficacy and economical standards (price factor).The formulation design consist of core tablets designed by direct compression method. Core tablets were coated with an naturally occurring swelling agent (carbopol & Karaya gum). Evaluation studies were performed for prepared pulsatile tablets hardness. In in vitro release profile of 6 hours study in first 5 hours it shows minimum drug release and at the end of six hours rapid and transient release was observed. Stability studies proved that coating of tablets seems to decrease the effect of temperature and moisture on degradation of Zafirlukast. The pulsatile release has been achieved from tablet over a 7-8 hour period.
Espacializando os lugares educativos
Authors: Neves Leonardo Longen , Campos Rosânia
Published: June 2020

Esse artigo aborda uma reflexão acerca das apropriações que as crianças fazem das instituições da educação infantil. Tendo por referencial teórico Michel de Certeau, abordamos as marcas das práticas infantis como elementos que evidenciam os movimentos de resistência sobre o ordenamento dos lugares no cotidiano das crianças. Partindo de um estudo de caso envolvendo três instituições dos três maiores municípios de Santa Catarina, as questões aqui apresentadas constituem um recorte de alguns elementos dessa pesquisa coletados por meio de registro fotográfico e analisadas a partir dos conceitos de espaço e lugar de Certeau.
Anti-oppressive social work practice in child welfare
Authors: Cowie Andrea
Published: June 2020

This article explores the journey of reconciliation, both personal and professional, required for the social work profession to shed its history of colonialism in the context of its relationship with Canada’s Indigenous People, particularly in the realm of child welfare. This process involves becoming accountable for past harms such as the residential school system, the mass removal of children during the ‘60’s scoop’, as well as the contemporary over-representation of Indigenous children in Canada’s child welfare system. Further, this process demands that non-Indigenous social workers locate their privilege in order to become effective allies and partners along this path of reconciliation.
The Sixties Scoop
Authors: Alston-O’Connor Emily
Published: June 2020

This paper examines issues concerning First Nations peoples and the child welfare system, and their implications for social work today. It explores the Sixties Scoop to illustrate the devastating impact such policies and practices had on Aboriginal children, families and communities. Cultural genocide is part of this legacy. To deliver more culturally appropriate services, awareness about and acknowledgement of these mistakes can assist social workers to incorporate a social justice perspective into their practice with Aboriginal clients. As well, implications for social work education regarding professional training, curriculum content and course delivery by Aboriginal faculty members are highlighted.
Oh Canada. Our Canada. One of Four Against
Authors: Graveline Fyre Jean
Published: June 2020

Oh Canada. Our Canada. One of Four Against.

DRUMFLUTESONG
A Genealogy of Poverty
Authors: O'Connell Anne
Published: June 2020

Genealogical investigations that attend to colonial rule reveal the intimate alliance between social welfare policy, racial slavery and modern power. In this paper, I intervene in the historiography of social welfare policy to disrupt a long line of academic study that severs studies on the poor from the history of racial slavery. This separation is enormously productive and conceals the ways in which knowledge systems and social policies are organized by and through racial ideologies, early liberalism and its use of population science. To illustrate this point, I show how concerns with knowing and targeting the bodies of poor and enslaved women helped formulate the new economy, white bourgeois power and the extension of empire.
Repositioning Social Work in Mental Health
Authors: Morley Christine , Macfarlane Selma
Published: June 2020

This paper emerges in response to the recent initiative by the Australian Association of Social Workers (AASW) to mandate the inclusion of specific, clinically based mental health curriculum into qualifying social work programs across Australia. Whilst the authors affirm the importance of an emphasis of mental health in social work education, we further suggest that the professional repositioning of social work in mental health must be informed by critical/postmodern theoretical approaches. If social work is to engender and maintain its unique and vital role in problematising simplistic, depoliticised and individualising constructions of mental health and illness, we need to promote more contextualised and holistic understandings of people’s experiences. The paper concludes by offering an example of critical mental health curriculum.
The Practical Realities of Ecosocial Work
Authors: Molyneux Rebecca
Published: June 2020

The following article examines contemporary literary opinion on the link between social and environmental justice. It argues that social work’s historical adherence to the notion of person-in-environment that is, person-in-social environment, has meant that environmental justice has not been widely realised in practice. Literature is drawn on to highlight the link between social and environmental justice and the relevance of environmental justice to social work practice. The author calls for additional debate on the merit of social work practice that realises the link between social and environmental justice and moreover, further research into how this link can be realised in practice.
Building Bridges and Crossing Boundaries
Authors: Coates John , Besthorn Fred H.
Published: June 2020

Where are the boundaries between things located? When we meet another person or when we meet the tree in the forest or the sand by the shore each is changed by the other. We all know that at one level of reality we are different and yet we also know that the apparent rigidity between me and other dissolves in a constant and mutual exchange of cells, conversations and consciousness. In nature, the bridge between two points of apparent difference is a dynamic, interactive field of reciprocal engagement. Indeed, in nature, complex, reciprocal relationships are the sine qua non of ecosystems. Everything touches and is touched by everything else. It is in meeting, touching, listening and communicating with another that we discover most completely what we are and are able to express most eloquently who we are.

The helping professions are increasingly seeking ways to bridge the epistemological gap between the atomistic and the ecological and cross those professional boundaries that have for too long kept helpers of every stripe separated and isolated from one another. Ironically, it is a new rediscovery of an ancient wisdom that is creating a catalyst for hope and change. Recently, those hopes to discover new linkages and a new era of collaborative professional partnerships to address pressing social and environmental problems took a small step forward. Professional helpers from a variety of disciplines including social work, psychology, nursing, education and environmental studies gathered in Calgary, Canada in May, 2009 for a first of its kind multi-disciplinary conference entitled: Building Bridges, Crossing Boundaries: Interdisciplinary Dialogues on Person, Planet and Professional Helping. The conference was suffused with both urgency and anticipation as professional helpers worked to better understand each other and those many ways they might cooperate across professional borders to build bridges to a more balanced and interdisciplinary view of the helping enterprise. This brief introduction provides a short sketch of the historical realities which created the ideological boundaries that the conference sought to bridge and how that has begun to change. It also provides a brief overview of each contributor’s work.