bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementasi Proyek Penguatan Profil Pelajar Pancasila (P5) Tema Gaya Hidup Berkelanjutan di SMAN 3 Padang Panjang
Authors: Amanda Zahwa Restu , Fernandes Reno
Published: July 2024

Penelitian ini menarik karena menganalisis implementasi proyek penguatan profil pelajar pancasila tema gaya hidup berkelanjutan di SMAN 3 Padang Panjang untuk membentuk karakter dan keterampilan siswa. Meski demikian ketika dilakukan observasi partisipan di SMAN 3 Padang Panjang menunjukan bahwa secara prosedural SMAN 3 Padang Panjang sudah melaksanakan projek P5 ini dengan maksimal, namun secara subtansial terdapat kendala. Penelitian ini bertujuan untuk menganalisis implementasi projek penguatan profil pelajar pancasila tema gaya hidup berkelanjutan di SMAN 3 Padang Panjang. Penelitian ini menggunakan pendekatan kualitatif dengan studi kasus. Data penelitian dianalisis menggunakan teori struktural fungsional dari Tallcot Parson dengan teknik pengumpulan data yang dilakukan melalui observasi, wawancara dan studi dokumen yang dilakukan bulan agustus 2023. Pemilihan informan menggunakan teknik purposive sampling, artinya informan yang dipilih memiliki informasi data yang dapat menunjang hasil penelitian yang berjumlah 10 orang, diantaranya 1 wakil kurikulum, 1 guru koordinator, 3 guru fasilitator dan 5 siswa SMAN 3 Padang Panjang. Peneliti melakukan triangulasi sumber dan teknik sebagai keabsahan data. Teknik analisis data yang dirujuk melalui pemikiran Miles dan Huberman, yaitu redusi data, penyajian data, dan kesimpulan. Hasil penelitian mengungkapkan bahwa secara prosedural SMAN 3 Padang Panjang telah dilaksanakan maksimal, namun secara subtansial terdapat kendala pada beberapa aspek, karena merupakan tahun pertama SMAN 3 Padang Panjang melaksanakan projek ini
Strategi Livelihood Peternak Sapi Perah Pada Masa Wabah Penyakit Mulut dan Kuku (PMK) di Desa Jetak Kecamatan Getasan Kabupaten Semarang
Authors: Serphina Selvi , Susanti Antik Tri , Hadiwijoyo Suryo Sakti
Published: July 2024

Penelitian ini bertujuan untuk mengidentifikasikan kondisi penghidupan serta mengkaji strategi penghidupan peternak sapi perah pada masa wabah penyakit mulut dan kuku (PMK) di Desa jetak Kecamatan Getasan Kabupaten Semarang. Penelitian ini dilakukan dengan metode kualitatif menggunakan paradigma kontruktivitis dengan teknik analisis data Miles dan Huberman (1984). Penelitian ini menggunakan teori Habitus Pierre Bourdieu dengan dasar analisis strategi livelihood tentang asset penghidupan DFID yang terdiri atas lima modal yaitu modal alam (natural capital), modal manusia (human capital), modal fisik (physical capital), modal sosial (social capital), dan modal finansial (financial capital). Teknik pemilihan informan pada penelitian ini menggunakan teknik purposive sampling dengan kriteria informan adalah masyarakat peternak sapi perah di Desa Jetak yang sapinya terkena wabah penyakit mulut dan kuku (PMK). Teknik pengumpulan data dalam penelitian ini dengan melakukan wawancara terhadap peternak sapi di Dusun Jetak, Legok, Kemiri, Setugur dan Kendal. Observasi dilakukan dengan mengamati aktivitas peternak sapi perah pada masa wabah penyakit mulut dan kuku (PMK) dan dokumentasi dengan cara mendokumentasikan sapi yang terkena wabah. Hasil dari penelitian ini menunjukkan ada perbedaan strategi bertahan antara peternak sapi kelas atas dan kelas menengah kebawah. Masyarakat peternak sapi perah kelas atas (yang memiliki 5 sampai 10 sapi), memikirkan strategi untuk meminimalisir resiko dari PMK dengan cara menjual sebagian hewan ternaknya, sedangkan bagi masyarakat kelas menengah kebawah (mempunyai maksimal 4 sapi) hanya pasrah. Mereka mengandalkan human capital dan social capital dalam strategi penghidupan dengan cara mencari pekerjaan sampingan seperti bercocok tanam cabai, jahe, dan tanaman keras, dibantu oleh anak sendiri dan dicukup-cukupkan untuk kebutuhan sehari-hari dari bantuan pemerintah.
Identitas Budaya Transmigran Jawa di Desa Rimbo Mulyo Kecamatan Rimbo Bujang Kabupaten Tebo
Authors: Marlina Yayuk , Syafrini Delmira
Published: July 2024

Penelitian ini menjelaskan tentang identitas budaya transmigran Jawa di Desa Rimbo Mulyo. Penelitian ini menarik untuk diteliti karena transmigran Jawa di Desa Rimbo Mulyo memiliki identitas budaya yang khas dan membedakan transmigran Jawa di daerah lainnya,  karena adanya percampuran antara budaya Jawa dengan budaya masyarakat setempat yang ber etnis Melayu Jambi. Penelitian ini menggunakan analisis teori identitas budaya oleh Stuart Hall dan Hommi K.Bhabba. Pendekatan penelitian menggunakan pendekatan kualitatif dengan tipe studi kasus. Pengumpulan informan menggunakan teknik Purposive Sampling dengan jumlah 16 orang, dengan kriteria masyarakat transmigran Jawa, keturunan masyarakat transmigran Jawa, masyarakat pendatang dan Kepala Desa Rimbo Mulyo. Pengumpulan data menggunakan teknik wawancara dimana peneliti dan informan melakukan tanya jawab secara tatap muka untuk menggali informasi, teknik observasi yaitu peneliti melakukan pengamatan atau catatan secara sistematik dan studi dokumen yaitu catatan peistiwa yang berbentuk foto dan dokumen mengenai informasi penelitian. Untuk mendapatkan keabsahan data, peneliti menggunakan teknik triangulasi data. Analisis data dilakukan dengan menggunakan model analisis Miles dan Huberman. Hasil penelitian menunjukkan bahwa masyarakat transmigran Jawa yang berada di Desa Rimbo Mulyo memiliki identitas budaya yang khas yang membedakannya dengan masyarakat Jawa di daerah lainnya: Pertama, Bahasa masyarakat transmigran Jawa. Kedua, Kesenian masyarakat transmigran Jawa. Ketiga, Tradisi Budaya masyarakat transmigran Jawa. Keempat, Sistem mata pencaharian hidup masyarakat transmigran Jawa. Kekhasan identitas budaya ini terjadi akibat proses adaptasi dengan budaya masyarakat setempat karena adanya proses interaksi yang cukup lama oleh masyarakat transmigran Jawa di Desa Rimbo Mulyo.
Perubahan Sosial Pada Komunitas Nelayan Pasca Pengembangan Danau Sipin Menjadi Destinasi Wisata di Kota Jambi
Authors: Nurbaiti Nurbaiti , Syafrini Delmira , Permata Bunga Dinda
Published: July 2024

Penelitian ini bertujuan untuk menganalisis bentuk perubahan sosial yang terjadi pada komunitas nelayan pasca pengembangan Danau Sipin menjadi destinasi wisata di Kota Jambi. Fenomena ini penting untuk dikaji sebab Danau Sipin yang semula dimanfaatkan oleh nelayan untuk memenuhi kebutuhan ekonomi mereka, pada tahun 2017 pemerintah setempat telah mengalihfungsikan danau tersebut menjadi destinasi wisata dengan menerapkan beberapa kebijakan sehingga menyebabkan jumlah nelayan dari tahun 2016-2021 mengalami penurunan sebanyak 57% akibat menurunnya pendapatan nelayan. Adapun Teori yang digunakan untuk menganalisis temuan hasil adalah teori struktural fungsional skema AGIL dari Talcott Parsons. Pendekatan penelitian yang diterapkan menggunakan pendekatan kualitatif tipe studi kasus. Penelitian berlangsung di Danau Sipin, Kecamatan Danau Sipin, Kota Jambi pada November 2023-Januari 2024. Pengumpulan data dilakukan melalui kegiatan observasi, wawancara mendalam dan studi dokumentasi. Teknik pemilihan informan penelitian melalui purposive sampling dengan informan sebanyak 26 orang terdiri dari nelayan, pedagang, pengunjung, tukang parkir, IRT, anak, dan tokoh masyarakat. Analisis data yang digunakan untuk menganalisis hasil temuan penelitian ini menggunakan model interaktif dari Miles dan Huberman. Hasil penelitian meliputi terjadinya: a) perubahan pada pola mata pencaharian sebagai bentuk perubahan yang dikehendaki dan direncanakan; b) perubahan peran ibu rumah tangga dalam keluarga sebagai bentuk perubahan kecil; c) perubahan sistem stratifikasi sosial pada nelayan; d) munculnya lembaga Pokmaswas perikanan dan Pokdarwis; e) perubahan kebiasaan nelayan; f) terjadinya perubahan pada desain dan arsitektur rumah sebagai bentuk perubahan yang tidak dikehendaki dan tidak direncanakan; g) munculnya inovasi dan ide kreatif pada bidang usaha dan tata ruang, dan; h) terjadinya perubahan pola interaksi sosial pada nelayan.
PENGARUH WORK FAMILY CONFLICT TERHADAP PARENTING STRESS IBU YANG BEKERJA
Authors: Rizal Gumi Langerya , Fikry Zulian
Published: July 2024

Zaman sekarang kebanyakan wanita tidak lagi hanya menjadi ibu rumah tangga tetapi juga ikut bekerja. Tuntutan perekonomian dan tingginya kompetitif di dunia kerja, mengharuskan ibu bekerja untuk memiliki komitmen besar dalam bekerja, namun dilain pihak banyaknya permasalahan anak dan remaja yang terjadi saat ini juga menuntut orangtua untuk mendedikasikan banyak waktu untuk keluarga terutama memberikan pengasuhan positif bagi anak. Menyeimbangkan tuntutan mengasuh anak dan tuntutan pekerjaan merupakan tantangan besar bagi ibu bekerja pada zaman ini. Adanya konflik peran ganda ini (Work Family Conflict) diduga dapat menimbulkan tekanan psikologi dalam mengasuh anak (parenting stress). Penelitian ini bertujuan untuk menguji pengaruh work family conflict terhadap parenting stress pada ibu yang bekerja. Penelitian dilakukan kepada 209 ibu bekerja di kota padang. Metode penelitian yang digunakan adalah metode kuantitatif terhadap data yang dikumpulkan menggunakan skala konflik kerja-keluarga (work-family conflict scale) dan Parenting stress scale. Hasil uji hipotesis dengan menggunakan analisis regresi sederhana menunjukkan bahwa terdapat pengaruh yang signifikan work family conflict terhadap parenting stress pada ibu yang bekerja.
ANALISIS CLASSROOM CLIMATE PADA UJI COBA PEMBELAJARAN TATAP MUKA (PTM) SAAT PANDEMI COVID-19
Authors: Aulia Raiza
Published: July 2024

This pandemic has changed all aspects of life, including the education system. The education system in Indonesia immediately turned online because it could not be done face-to-face. Gradually, the government began to study to restart new normal and conduct face-to-face trials for students, especially high school students in Surabaya. The data collection technique used interviews with students as participants and teachers as a significant other. The author takes the context of classroom climate because face-to-face learning trials are still being reviewed by the local city government to regulate the course of learning in accordance with health protocols. There are three dimensions in the classroom climate, namely relationships, personal growth and development and system changes and improvements. The results of the student interviews showed that they were uncomfortable with face-to-face learning because they felt awkward, uncomfortable in entering the classroom and needed to adapt directly to the teacher, while according to the teacher, the students were very enthusiastic about the face-to-face learning trial.
Štrukturalizmus a jeho vplyv na vybrané oblasti slovenskej lingvistiky
Authors: Chomová Alexandra
Published: July 2024

Contemporary Slovak linguistics has built upon the research tradition arising from the field’s earlier stages of development. Modern linguistic trends active since the 1920s have also influenced Slovak linguistics significantly. Based on the examination of scholarly articles from that period, this paper aims to assemble a selection of information related to the establishment of a new linguistic trend – structuralism – in Slovak linguistics in the context of Czechoslovakia. The cultivation of theoretical discussions in the post-war period – connected with the organization of linguistic research in Slovakia – is observed on the basis of contemporary Slovak and Czech linguistic texts on selected linguistic topics written from the 1930s to the 1970s. Apart from that, publications evaluating the presence of structuralism in Slovak linguistics are also examined (e.g. Anton Popovič, Ľubomír Ďurovič, Ján Kačala, Rudolf Krajčovič and František Štraus). The paper focuses on the beginnings of structuralism in Slovak linguistics, devoting attention to the Bratislava Linguistic Circle (1945) and its activities. Views of neogrammarianism and structuralism are observed, for in Slovak linguistics such views influenced the way the Czechoslovak question was perceived, while also informing research into phonology, dialectology, morphology and syntax, as well as lexis and language culture. The paper also traces the impact of particular views on educational practice.
RENAL TUBULAR ACIDOSIS DUE TO SJOGREN'S SYNDROME PRESENTING AS HYPOKALEMIC QUADRIPARESIS: A CASE REPORT
Authors: Khurshid Fatima ,   Shifa International Hospital ltd. Islamabad, Pakistan
Published: July 2024

Sjögren's syndrome is characterized by dry mouth and eyes symptoms caused by lymphocyte infiltration of the exocrine glands as it is an autoimmune condition. Nonetheless, this condition can lead to symptoms and various illnesses. Renal tubular acidosis (RTA) occurs when the kidney tubules are unable to regulate acid-base balance. This study tracked a 40-year-old female who initially showed symptoms of hypokalemic stroke and normal anion gap acidosis and was later determined to have Sjögren's syndrome. The patient complains of weakness in the legs, vomiting, abdominal pain and dry cough. Like other Sjögren's symptoms, dry eyes and mouth have been present for years. Electrolyte abnormalities and lymphocytic infiltration in the lymph nodes can be confirmed by physical examination and laboratory tests. Positive antibodies, Schirmer test, and histology results indicate the diagnosis. Treatments include potassium replenishment, artificial tears, and the use of coconut oil. Early diagnosis and treatment can help prevent the condition from worsening and improve patient outcomes. It also emphasizes the importance of completing a comprehensive evaluation that includes organ system and specific markers of disease.
The Time-Space Regimes of Human Mobility in the North Atlantic Island Spaces (Iceland, Azores, Madeira, the Canary Islands, and Cape Verde)
Authors: Jerez-Darias Luis Manuel , Domínguez-Mujica Josefina
Published: July 2024

Throughout history the North Atlantic archipelagos have projected themselves outwards thanks to travel and the innate capacity of their inhabitants to relate to other peoples. This research aims to reveal their nodal character on the stage of global mobility, using a detailed statistical analysis of their migration trends since the 1960s. To this end, it is necessary to recognise the rhythms of the migration transition and its parallelism with the socio-economic development of the island spaces themselves. In addition, common features can be identified in their recent migration patterns in which a great diversification of origins and destinations predominates, as well as a multiplicity of motivations. With this aim, migration in these archipelagos is interpreted from a temporal and spatial perspective, redefining the historical concept of “Atlanticity,” and allowing to identify the strategic position they play in the geography of human mobility in times of global capitalism.
Small Islands and Islets: Laboratories or Key Sensors for Environmental Policies in the Mediterranean Basin?
Authors: Crouteix Orianne
Published: July 2024

By building the PIM Initiative, the European and International Delegation of France’s Conservatoire du Littoral et des Rivages Lacustres (Coastal Protection Agency) aims to use small islands as laboratories to unite actors and build ambitious environmental policies in the western Mediterranean basin. This study examines the position of these small islands as a relevant model for conservation policies and actions. It is based on data collected during a two-year immersion in the PIM Initiative and uses several methodological and analytical tools. While working on the small islands of the Mediterranean basin, the PIM Initiative uses three main techniques: building a collective, gathering environmental data, and spreading a representation of these territories to wider publics. These techniques are analyzed using the framework of the circulatory system of scientific facts (Latour, 1999). This analysis highlights three preconceptions: (i) small islands group a limited number of actors, (ii) islands attract and facilitate consensus, and (iii) actions implemented on small islands can be replicated on larger islands and the mainland. The article concludes by discussing how the PIM Initiative is poised between considering small islands as laboratories which should become models for environmental policies, or as key sensors, specific territories which highlighted some broader features.
Identification of microglia and macrophages using antibodies to various sequences of the Iba-1 protein
Authors: Razenkova VA , Kirik OV , Pavlova VS , Korzhevskii DE
Published: July 2024

The Iba-1 protein is traditionally considered a highly selective marker of microglia because of the specific expression of the gene in this particular population of the CNS cells. Alternative splicing creates several isoforms of the Iba-1 protein, which may cause discrepancies in the results of immunohistochomic reactions depending on which epitopes of the immunogen the antibodies selected for the study were developed. In this connection, and with the aim at identifying reliable variants of antibodies to Iba-1 available to researchers in the Russian Federation, we organized with study, seeking to evaluate the results of detecting microglia and macrophages using antibodies to different protein sequences produced by different manufacturers. As material, we used samples of the brain and testis of sexually mature (3–5 months) male Wistar rats (n = 8). Polyclonal and monoclonal (clone JM36-62) antibodies to Iba-1 were used as primary reagents. We found that monoclonal antibodies of the JM36-62 clone enable more selective antigen detection with a better signal/background ratio; they can be used as replacements for reagents that are currently not available commercially. Polyclonal antibodies enabled not only immunospecific imaging of microglia and macrophages, but also the identification of cells of the epithelial-spermatogenic layer of the testis. It is assumed that epithelial-spermatogenic layer contains the Iba-1 isoform devoid of an epitope that corresponds to the sequence of the immunogenic antibody clone JM36-62 fragment of the native protein. Functionally, various isoforms of Iba-1 should be investigated further.
Efficient Resource Allocation in Virtual Power Plant for Real-Time Energy Market Framework
Authors: Amissah Jeremiah ,   Department of Electrical Power Engineering Egypt-Japan Univeristy of Science     and Technology, New Borg, El-Arab City. Egypt, Abdel-Rahim Omar , Mansour Diaa-Eldin A. , Asano Tanemasa , Abdelkader Sobhy Abdelkader ,   Electrical Engineering Department, Mansoura University. Egypt,   Department of Information Electronics, Kyushu University, Fukouka, Japan
Published: July 2024

The increasing evolution of the global energy landscape has made the adoption of distributed energy resources (DERs) and the emergence of virtual power plants (VPPs) crucial for the development of sustainable and efficient energy systems. This paper delves into the critical aspect of efficient DER coordination within VPPs, especially tailored to real-time market framework. The enhanced pelican optimization algorithm (enhanced POA), which is used in this paper, enhances the VPP's capacity to adjust to rapidly shifting energy demands and market dynamics. This effort attempts to build a complete framework that ensures economic feasibility while maximising efficiency by utilising the combined potential of diverse DERs, including storage systems and renewable energy sources. The paper compares the proposed resource allocation technique with other evolutionary algorithms and evaluate its performance in several case studies using thorough simulation and analysis. With a 8% decrease in energy expenses when compared to other algorithms, the results offer insightful information about optimizing VPP operations and provide a route toward a more adaptable, sustainable, and robust energy management system.
Balcony solar photovoltaic plug-and-play systems
Authors: Seme S. ,   Faculty of Energy Technology, University of Maribor. Slovenia, Strojansek L. , . Simonic E. , Sredensek K. ,   Faculty of Electrical Engineering and Computer Science, University of Maribor.     Slovenia
Published: July 2024

The paper presents balcony solar photovoltaic plug-and-play systems with a capacity of up to 600 W. Balcony solar photovoltaic plug-and-play systems up to 600 W are categorized under plug-in renewable energy production devices. The feasibility of investing in a balcony solar photovoltaic plug-and-play system was analyzed using 15-minute data on electricity consumption for various household consumers. Data on the power density of solar radiation obtained from the online archive of automatic weather stations of the Slovenian Environment Agency were used to calculate the anticipated electricity production of the balcony solar photovoltaic plug-and-play systems. Based on these data, the annual electricity production for various household consumers using a balcony solar photovoltaic plug-and-play system was calculated. The payback period of the investment was calculated considering the current prices of balcony solar photovoltaic plug-and-play systems in the Slovenian market. It also showed how the payback period of the investment is affected by changes in electricity prices for high and low tariffs and by changes in the electricity consumption of the household consumer. Key words. the photovoltaic system, distributed generation, plug-and-play solar, household consumers, electricity market
A proposal of anomaly detection method based on natural data augmentation in the Eigenspace
Authors: Murakami Naoki ,   Chukyo University, Hiramatsu Naoto , Hiroki Kobayashi , Akizuki Shuichi , Hashimoto Manabu ,   Chukyo University,   Chukyo University,   Chukyo University,   Chukyo University
Published: July 2024

This paper proposes a natural data augmentation method and an anomaly removal artificial neural network for accurate anomaly detection. Anomaly detection is important because the provision of high-quality products is vital in the manufacturing industry. However, it is difficult to obtain a sufficient number of anomaly samples for the detection, which represents a significant challenge when it comes to achieving accurate anomaly detection by machine learning. General data augmentation methods generate new anomaly images by combining normal images and anomaly images. As an alternative, this paper describes a method that generates new anomaly images by using the Eigenspace. More natural anomaly images are generated than with general data augmentation methods. This paper also proposes an anomaly removal neural network that utilizes this natural data augmentation. The results of an anomaly detection experiment showed that the AUC of 94.7% was achieved for the capsule dataset when using anomaly images generated by the proposed data augmentation for training the anomaly removal neural network. This is 1.3% higher than the state-of-the-art data augmentation method that has been utilized for training the neural network. In the case of the pill dataset, AUC of 99.4% was achieved by proposed method. This is 3.0% higher than the state-of-the-art data augmentation method that has been utilized for training the neural network. The results of a series of experiments demonstrated that anomaly images generated by the proposed data augmentation are effective for training the neural network.
Hacia la implementación de la perspectiva de la diversidad sexo genérica en el ejercicio del Trabajo Social con personas transgénero
Authors: Cortadi Boyra María
Published: July 2024

Este artículo aborda necesidades y buenas prácticas en la intervención psicosocial con personas trans, una realidad sobre la que cada vez existen más estudios, aunque no es un campo altamente explorado. Para ello, explora las problemáticas y necesidades de este colectivo altamente estigmatizado, así como la intervención psicosocial con el mismo, mediante entrevistas en profundidad con profesionales que tienen experiencia tratando con él en diferentes ámbitos (prostitución, sinhogarismo, atención al colectivo LGTBI+…). Los resultados obtenidos muestran la necesidad de la aplicación de la perspectiva de diversidad de género y sexual en las intervenciones psicosociales que se realizan con estas personas, la perspectiva de les profesionales sobre las necesidades de la intervención psicosocial actual, como la necesidad de más formación, y aspectos esenciales y propuestas de mejora en la intervención, como planes de prevención de problemas de salud mental.
Research of Hybrid Aluminium Castings with the Use of Porous Cores
Authors: Brůna M. , Medňanský M. , Oslanec P.
Published: July 2024

The paper focuses on the research of hybrid aluminium castings produced by overcasting technology. This is an advanced technology for ensuring the lightness of castings by using the principle of overcasting a core with a porous cellular structure produced by foaming. Process parameters in the foaming phase of the material have a great influence on the resulting porous structure. The article focuses on controlling the influence of pressure during the foaming process on the resulting porosity and evaluating by X-ray tomograph and measuring the relative density. Variants using an initial pressure of 0.3 MPa appear to be the most satisfactory. The challenge of this technology is to ensure adequate bonding of the metals at the interface between the porous core and the solidified metal without penetrating the coating layer. For this reason, the surface treatment of foamed cores with various etchants has been proposed to disrupt the oxide layer on their surface. Macrographs of the uncoated sample and samples etched with 0.5% HF and 10% H3PO4 demonstrated the need for core surface treatment to prevent liquid metal penetration. EDX analysis confirmed the presence of AlPO4 at the core/casting interface in the treated sample.
Oral health problems and their management in patients with Down Syndrome—a narrative review
Authors: Torlińska-Walkowiak Natalia , Huang Yu-Wei , Wyzga Sylvia , Opydo-Szymaczek Justyna
Published: July 2024

Patients with Down Syndrome (DS) commonly exhibit various anomalies in the masticatory organ and oral cavity. This paper aims to consolidate information regarding oral health challenges faced by individuals with DS, along with strategies employed for their management and care. Our review, conducted via PubMed and Scopus, spanned the period from January 1977 to December 2023. It included original research articles and comprehensive reviews focusing on both pediatric and adult populations. The paper analyzes 71 articles, categorizing them into six sections: oro-facial problems, tooth conditions, dental and skeletal age, dental caries, periodontal diseases, swallowing, masticatory muscles, salivation, behavior management, physical therapy, and early intervention. Understanding oral health issues in individuals with DS is crucial for providing tailored dental care and treatment planning. Regular dental assessments, early intervention strategies such as physiotherapy and behavioral management, and a collaborative approach involving oral health professionals, caregivers, and the individuals themselves are critical to preventing oral health issues and improving overall health and well-being in people with DS.
A strategy for covalent anchoring of self-assembling β3 oligoamide nanorods to gold surfaces
Authors: Hussein Khadeeja A. , Kulkarni Ketav , Barlow Anders , Perlmutter Patrick , Mechler Adam
Published: July 2024

Oligopeptides stand out for their remarkable structural variability, ease of synthesis, and amenability to functionalization, making them exceedingly appealing for crafting functional nanostructured materials. The low metabolic stability of natural peptides can be overcome by replacing α-amino acids with β3- amino acids, to yield artificial peptides best described as substituted β3-oligoamides. Controlling the morphology of such structures by varying the amino acid residues and altering the oligoamide termini makes it possible to adapt the core design to a range of hierarchical structures and function. Conductivity is a desired property in such nanomaterials; preferably conductive materials should be chemically anchored to a highly conductive metal, such as gold surface to connect to macroscopic electronics. It is preferable to use thiol functionality, however β3 cysteine is not synthetically achieveable. In this study β3 [SLIA] oligoamide has been synthesized and functionalized at the N terminus with a thiol moiety. After successful synthesis and purification, the thiolated oligoamide was physically characterized to confirm binding to gold, self-assembly and hetero assembly on these anchor points. It was demonstrated with a quartz crystal microbalance (QCM) that self-assembling monolayers can be formed on a gold surface and the formation of a S-Au bond was confirmed with X-ray photoelectron spectroscopy. Growth of Ac-β3[WKLWEL] fibres on these anchor points was confirmed by using atomic force microscopy and QCM. Hence, a viable metal anchor has been established that lays the foundations for the future development of molecular electronics based on β3 oligoamides.
Effects of valproic acid on transcript levels in neurotrophin signaling pathway in mice hippocampus according to the implementation period
Authors: Gök Duygu Kurt , Erdoğan Füsun Ferda , Göl Mehmet Fatih , Taheri Serpil , Önal Müge Gülcihan , Şükranlı Zeynep Yılmaz , Güvenilir Ecma , Yora Samed
Published: July 2024

Background/Aim

Valproic acid (VPA), is an antiepileptic drug and it has been known for a long time that exposure to VPA in the fetal period causes many behavioral, cognitive, and structural disorders. In this study, we aimed to evaluate the effects of the implementation period of VPA during pregnancy on both behavioral tests and the expression of 45 key genes belonging to the neurotrophin signaling pathway.

Methods

The study was designed to form four different groups of five female mice in each group. The experimental and control groups were divided into mature (n = 5) and immature (n = 5) subgroups, respectively. VPA (500 mg/kg dose) was subcutaneously administered to the experimental groups. All mice were first tested for behavioral changes, and then the hippo-campal tissues were used for RNA isolation. The expression levels of 45 transcripts associated with the neurotrophin signaling pathway were determined by real-time RT-PCR in the hippocampus.

Results

No differences were found between the groups in any of the behavioral tests. When gene expression was examined, there was a difference between the groups in the transcript levels of Ngf(neurotrophic growth factor), Ntrk2 (neurotrophic receptor tyrosine kinase 2), Shc1 (SHC adaptor protein 1), Chka (choline kinase alpha), and Mapk1 (mitogen-activated protein kinase 1) genes.

Conclusions

This study demonstrated the effects of VPA on transcript levels at different maturation stages. We believe that it is important to explain the structural and cognitive teratogenic side effects caused by VPA in human fetuses using genes whose expression changes.
Promoting International Scientific Cooperation: the Role of Scientific Societies
Authors: Vráblová M. , Bonetti G. , Henehan G. , Brown R. E. , Sykora P. , Marks R. S. , Miertus S. , Lorusso L. , Tartaglia G.M. , Cerkez Ergoren M. , Sait Dundar M. , Dundar M. , Michelini S. , Miertus J. , Connelly S.T. , Martin D. , Bacu A. , Herbst K.L. , Bertelli M.
Published: July 2024

Scientific collaboration yields many advantages, especially in fields that require interdisciplinary approaches, as it fosters the sharing of knowledge and resources and is essential for the implementation of complex projects. The concept of scientific internationalism emerged around the 1900s, emphasizing that science surpasses national boundaries and promotes global peace and collaboration. International scientific cooperation is halted by geopolitical tensions and conflicts, such as World War II and the Cold War. Nevertheless, many examples show that scientific collaboration can surpass conflicts and bring scientific and society development, such as in the cases of the Tick-borne Encephalitis vaccine, the Apollo-Soyuz test project and more recently the international endeavour for COVID-19 vaccine development. In this contest, UN and WHO have an imporant role to promote peace and scientific cooperation, examplified by the 16th Sustainable Development Goal, to “Promote just, peaceful and inclusive societies”.

This review aims to assess the available literature regarding international scientific collaboration and the role of scientific societies in promoting scientific cooperation.

Scientific societies have proved to be pivotal in bridging cultures and promoting international cooperation. Apart from the historical example of the International Institute for Applied Systems Analysis, which showed an important cooperation between Western and Eastern countries during the Cold War, the scientific society European Biotechnology thematic network Association (EBTNA) has international scientific cooperation as one of its critical goals.

Scientific societies such as EBTNA will be pivotal in promoting international scientific cooperation and fostering international activities and scientific research.
The future of European universities on the path to sustainable development
Authors: Korzeb Zbigniew , Alonso-Fariñas Bernabé , Irimia-Diéguez Ana Isabel , Naharro Felix Jimenez , Kobylińska Urszula , Pietro Filippo di , Sanchez Maria Jose Palacin , Rollnik-Sadowska Ewa , Szpilko Danuta , Szydło Joanna , Gallegos Antonio de la Torre
Published: July 2024

The article addresses the issue of the future of European universities on the path to sustainable development. The main aim of the article is to describe foreseeable future directions of the sustainable development of universities and ways to achieve Sustainable Development Goals. In effect, the authors identify weaknesses, assess threats and recommend coordinated solutions and alternatives for the sustainable development of universities. This research will contribute to future work by explaining what the future of universities will look like on their sustainability journey. The results of the Delphi study conducted with the participation of 201 experts from 47 countries allowed for the identification of factors shaping the future of universities on the path to sustainable development.
Towards a taxonomy of design options for augmented reality-based remote service business models
Authors: Ohlig Stefan , Breitkreuz David , Aliyu Aliyu , Mishra Rakesh , Stegelmeyer Dirk
Published: July 2024

The aim of this paper is to develop design options for Augmented Reality (AR)-based remote service business models to support the implementation of AR technology for remote services currently taking place in the manufacturing industry. The design options were developed using a qualitative content analysis based on the results of a systematic literature review and on focus group discussions with 19 service-responsible industry experts from 12 German manufacturing companies. The application of a conceptual approach to taxonomy development resulted in a novel morphological framework with a total of 18 dimensions, each with two to six distinct characteristics representing the targeted design options of AR-based remote service business models. Since previous research on AR for remote services has largely neglected the business model perspective, this work makes a significant contribution to this scarcely explored research field by providing a systematic basis for describing and classifying such business models in terms of their design. The results provide industrial practice with the most important aspects to consider when designing AR-based remote service business models.
Comparative effect of biopesticides against the fall armyworm Spodoptera frugiperda (J.E. Smith)
Authors: Atta A.A.M. , Al-Ayat A.A. , Gad H.A. , Abdelgaleil S.A.M.
Published: July 2024

The current study evaluated the effect of microbial-derived insecticides (abamectin and spinosad), two microbials (Beauveria bassiana (Balsamo) Vuillemin, Bacillus thuringiensis Berliner), and three chitin synthesis inhibitors (CSIs) (chlorfluazuron, hexaflumuron and lufenuron) against Spodoptera frugiperda larvae. Spinosad and abamectin caused pronounced mortality against second larval instar of S. frugiperda using the leaf dipping method. Spinosad induced higher toxicity (LC50 = 4.01 mg/L) than abamectin (LC50 = 8.33 mg/L) one day after treatment. The treatments with B. bassiana and B. thuringiensis caused higher mortality of S. frugiperda larvae 7 days after treatment with LC50 values of 3.0 × 105 spores/ml and 8.2 × 106 cells/ml, respectively. In the case of the CSIs, hexaflumuron showed higher toxicity than chlorfluazuron and lufenuron with LC50 values of 0.01, 0.009 and 0.005 mg/L 3, 7 and 10 days after treatment, respectively.
Antibacterial potential of extracts and metabolites isolated from the endophytic fungus Chaetomium cochliodes against phytopathogenic bacteria
Authors: Saad M.M.G. , Abdelgaleil S.A.M.
Published: July 2024

Five fungal endophytes, Alternaria sp., Aspergillus sp., Chaetomium sp., Rhizopus sp. and Curvularia sp., were isolated from an Egyptian herbaceous plant, Tribulus terrestris, and tested for their antibacterial activity against three phytopathogenic bacteria (Pectobacterium carotovorum subsp. carotovorum, Ralstonia solanacearum, Pseudomonas syringae pv. syringae). Chaetomium sp. showed the highest antibacterial activity. This strain was identified morphologically and molecularly as Chaetomium cochliodes MS03 (MW898133) based on the ITS1-5.8S rRNA-ITS2 genomic region. Chaetomium cochliodes caused 15 and 8 mm inhibition zones of P. carotovorum subsp. carotovorum and R. solanacearum, respectively. Chaetomium cochliodes isolate was fermented and extracted with ethyl acetate. The crude extract of C. cochliodes showed strong antibacterial activity against P. carotovorum subsp. carotovorum (inhibition zone = 27 mm). Bioassay guided isolation of the crude extract using silica gel column chromatography was conducted to isolate bioactive secondary metabolites. Minimum inhibitory concentrations (MICs) were 500, 32 and 4 mg/L for C. cochliodes extract, fraction 14 and fraction 15, respectively, against P. carotovorum subsp. carotovorum. Bioactive fractions were analyzed by GC/MS. The bioactive pure compound was identified as 9,12-octadecadienoic acid (Z,Z) and the chemical structure was confirmed by H1 NMR and C13 NMR spectral analysis. The isolated compound showed a promising antibacterial activity against P. carotovorum subsp. carotovorum with MIC value of 32 mg/L.
First record of Hyphopichia burtonii isolated from the storage pest Sitophilus zeamais and its bioactivity against mycotoxigenic fungi
Authors: Seco M.N.P. , Beltran A.K.M. , Balendres M.A.O.
Published: July 2024

Corn weevil (Sitophilus zeamais) is one of the most destructive pests of corn seeds during storage. The weevil may be a vector of mycotoxigenic fungi or yeast contaminating seed lots. In this study, an unknown yeast species was isolated from corn weevils found in stored corn seeds. We hypothesized that this yeast had an antifungal activity thereby inhibiting growth of mycotoxigenic fungi in corn seeds. The yeast species was identified as Hyphopichia burtonii, using combined morphological and molecular assays, and its potential inhibitory activity was assessed in vitro (spread plate and dual culture) against three known mycotoxigenic fungi, Fusarium verticillioides, Aspergillus niger and A. fl avus. Screening of the antagonistic activity of the yeast isolate showed 50 – 69% colony growth inhibition of three fungi when the yeast was spread plated on PDA but only slight inhibition (5.8 – 13.7% growth inhibition) in the dual culture assay. The sporulation of the fungi was also affected at 57 – 96% and 29 – 40% in spread plating and dual culture assay, respectively. In addition, volatile and non-volatile fractions also showed a reduction in mycelial growth. Variable responses were observed among the mycotoxigenic fungi. Further research would be interesting on the potential utilization of the antagonistic yeast to reduce fungal growth and sporulation, and possible mitigation of mycotoxin contamination in corn grains. To our knowledge, this is the first record of H. burtonii isolated from an insect, specifically S. zeamais.
Population monitoring and status evaluation of the new invasive pest, Drosophila suzukii (Matsumura) (Diptera: Drosophilidae), in various crop systems of Georgia (Sakartvelo)
Authors: Japoshvili G. , Murvanidze M. , Inasaridze N. , Meskhi N. , Lipartia Z. , Namicheishvili L.
Published: July 2024

The spotted wing drosophila, Drosophila suzukii (Matsumura, 1931), population fluctuations and distribution were monitored in four susceptible crops (blueberry, strawberry, cherry, wine grapes) and five major agricultural regions of Georgia (Guria, Samegrelo, Imereti, Kartli and Kakheti) during the years 2021 and 2022 with the aim to study the population size and evaluate the pest status. Population monitoring was conducted in four locations of each studied region on a weekly basis from May to November using PHEROCON® SWD traps with PHEROCON® SWD PEEL-PAK™ Broad Spectrum Lures. The investigation indicated significant growth of population from 2021 to 2022 in most of the studied locations. Population increase was detected in all crop orchards except cherries. Τhe absence of alternative host plants at crop proximity was of critical importance to save the crop from pest invasion. The crop plant species did not have a significant impact on D. suzukii. Pest population was significantly larger in summer and autumn compared to spring, possibly influenced by the ripening of alternative crops such as blackberry and elderberry. The sex ratio between male and female individuals was almost 1:1 and remained consistent through the two-year study period and across regions. We consider that D. suzukii entered the country from the southwestern part and extended its distribution range towards the east. No strategies for D. suzukii control have been elaborated in Georgia so far. Sprays of effective pesticides based on pest monitoring as well as sanitation measures involving removal of alternative host plants and any crop residues from the field are necessary to avoid pest outbreak.
Implementation of Classical Motion Cueing Algorithms for Serial Manipulator Based Motion Simulator: Larrmos Case Study
Authors: Stupans A. , Maksimkins P. , Senfelds A. , Ribickis L.
Published: July 2024

The study focuses on the development and evaluation of a motion control system for the Large Range Robotic Motion Simulator (LaRRMoS), which is based on a serial manipulator with 6 degrees-of-freedom. Two motion cueing algorithms (MCAs) – Classical Washout Filter (CWF) and Classical Washout Filter with Cylindrical coordinates (CYL) – are implemented and tested for simulation fidelity and LaRRMoS workspace utilization. CWF and CYL motion cueing performance gets assessed in two use cases: car simulation and luge sports simulation. The car case is a typical driving simulator application. The luge sports case is chosen for its high dynamics to assess the limits of the robot and motion cueing. Though this study uses a pre-recorded set of motion data and runs simulations in non-interactive mode, it aims for real-time interactive simulation for LaRRMoS in the future, so only MCAs capable of real-time operation are inspected. Conducted tests show that the CYL algorithm provides superior performance in highly dynamic motion replication, particularly in lateral accelerations.
Characterisation of Hybrid Photodetector Signals for Satellite Laser Ranging Application
Authors: Salmins K. , Kaulins J.
Published: July 2024

The hybrid photodetector (HPD) is a photomultiplier tube combined with the semiconductor device within the vacuum. The photoelectrons emitted from the photocathode directly hit the semiconductor enabling efficient electron multiplication with low noise and symmetric output pulse. These properties make a hybrid photodetector a good solution for photon-counting applications. At the Satellite Laser Ranging Station of the Institute of Astronomy at the University of Latvia, the hybrid photodetector characteristics were evaluated for SLR applications, including multiphoton mode and time-walk compensation.
Comparative Analysis of Thermal Characteristics: Virgin Polyacrylonitrile (PAN) Versus Electrospun Pan Nanofibre Mats
Authors: Sanchaniya J. V.
Published: July 2024

The utility of polymers in the fabrication of nanofibres via electrospinning is well established. Paramount to their application is understanding of their thermal properties, as these dictate not only their processability but also their mechanical robustness, stability under elevated temperatures, and suitability for intended applications. The electrospinning process, which involves heating polymers and subjecting them to high voltage, inherently modifies their thermal characteristics. This study attempts to elucidate these alterations, particularly by focusing on polyacrylonitrile (PAN) nanofibres. Employing techniques such as thermogravimetric analysis (TGA) and Differential Scanning Calorimetry (DSC), the study compares the thermal properties of electrospun PAN nanofibre mats with those of their virgin counterparts. The PAN nanofibres were synthesised by electrospinning the PAN polymer solution and collecting the resultant mat on a flat plate collector. For a comparative analysis, virgin PAN, from which nanofibres were derived, underwent identical thermal testing. The findings reveal a reduction in the glass transition temperature of PAN nanofibres by approximately 3–5 % compared to virgin PAN. In addition, a significant reduction in heat capacity of about 42 % was observed in the nanofibres. Additionally, the TGA results indicated solvent evaporation at approximately 110 °C. Therefore, this investigation sheds light on the nuanced alterations in the thermal characteristics of PAN nanofibre mats as a result of the electrospinning process, providing vital insights for their application in various thermal management scenarios.
Digital Psychosocial Follow-up for Childhood Critical Illness Survivors: A Qualitative Interview Study on Health Professionals’ Perspectives
Authors: Hagen Marte Hoff , Hartvigsen Gunnar , Jaccheri Letizia , Papavlasopoulou Sofia
Published: July 2024

Background

Digital solutions have been reported to provide positive psychological and social outcomes to childhood critical illness survivors, a group with an increased risk for long-term adverse psychosocial effects.

Objective

To explore health professionals’ perspectives on the potential of digital psychosocial follow-up for childhood critical illness survivors.

Methods

Using a qualitative approach, expert interviews with six health professionals working at a Norwegian hospital were conducted. Transcribed interviews were analyzed using Braun and Clarke’s six-phase thematic analysis framework. Concurrent data collection and analysis using inductive coding was also employed, and a model of codes was constructed.

Results

The interview yielded thirteen unique codes regarding the health professionals’ perspectives on the potential for digital psychosocial follow-up for childhood critical illness survivors, organized in a model comprising the two main themes: Affecting Factors and Digital Usage. Demographic factors (the child’s medical condition, age, gender, and residence) and environmental factors (the child’s family and health professionals) tended to affect the current psychosocial follow-up. Hospital limitations concerning a lack of digital solutions, worse relationship building with video communication, and children’s already high screen time reflected the current state of digital usage. However, ongoing digitalization, existing successful digital solutions, children’s good digital skills, and an ongoing process of creating an artifact are also seen as opportunities for digital usage in future psychosocial follow-up for childhood critical illness survivors.

Conclusions

Researchers can build further on these findings to investigate the potential of digital psychosocial follow-up for childhood critical illness survivors, and clinicians can use it as a starting point for improving psychosocial follow-up.