bluuebunny/crossref_metadata_2025 huggingface dataset:
Reliability of hemoglobin A2 value as measured by the Premier Resolution system for screening of β-thalassemia carriers
Authors: Satthakarn Surada , Panyasai Kesorn , Phasit Amphai , Panyasai Sitthichai
Published: October 2023

Objectives

Accurate quantification of hemoglobin (Hb) A2 is vital for diagnosing β-thalassemia carriers. This study aimed to assess the precision and diagnostic utility of HbA2 measurements using the new high-performance liquid chromatography (HPLC) method, Premier Resolution, in comparison to capillary electrophoresis (CE).

Methods

We analyzed 418 samples, previously identified as A2A by CE, using Premier Resolution-HPLC. We compared the results, established correlations, and determined an optimal HbA2 cutoff value for β-thalassemia screening. Additionally, we prospectively evaluated the chosen cutoff value in 632 samples. Mutations in the β- and α-globin genes were identified using polymerase chain reaction (PCR) techniques and DNA sequencing.

Results

HbA2 levels were consistently higher with Premier Resolution, yet there was a significant correlation with CE in all samples (bias, −0.33; r, 0.991), β-thalassemia (bias, −0.27; r, 0.927), and non-β-thalassemia carriers (bias, −0.36; r, 0.928). An HbA2 cutoff value of ≥4.0 % for β-thalassemia screening achieved 100 % sensitivity and 99.6 % specificity. Further validation yielded sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 97.3 , 99.8, 97.3, 99.8, and 99.7 %, respectively. We also identified a rare β-Hb variant, Hb La Desirade [HBB:c.389C>T], associated with β-thalassemia and co-inherited with a single α-globin gene.

Conclusions

The Premier Resolution HPLC is a reliable and accurate method for routine β-thalassemia carrier screening, aligning with existing CE methods.
Turning the tables on online exam cheating via language mediation tasks
Authors: Chovancová Barbora , Bilová Štěpánka , Hradilová Alena
Published: October 2023

This article addresses the issue of foreign language testing in the online mode and proposes a strategy to reduce the possibility of academic misconduct, specifically cheating, by designing tasks that assess the language skill of mediation in Legal English exams. Such tasks require test-takers to generate original answers, which can significantly reduce the risk of copying and pasting. Additionally, mastering the skill of mediation is a valuable asset for future lawyers. The authors introduce two original distinct intra-language mediation tasks that they developed for assessing English for Legal Purposes. One is aimed at first-year students with limited Legal English experience, while the other is intended for more advanced and experienced students. The article analyses student responses and evaluates their performance. The authors follow the action research approach, which involves a circle of observing, reflecting and acting, and raise questions concerning the originality of answers, production of a measurable sample of the target language, objectivity of assessment, and whether the practice in class impacts the success rate. The article also discusses challenges encountered during the process and how they were addressed. It can be concluded that mediation tasks are practical for online testing but could be used equally well for traditional classroom assessment.
Virtual planning for corrections of hemifacial microsomia
Authors: Sugar Adrian , Evans Peter , Bartlett Scott , Key Steven
Published: October 2023

Objectives

This article describes the many anomalies within and outside the head and neck of hemifacial microsomia (HFM).

Methods

The OMENS+ classification system is described with particular reference to the mandibular features classified by Pruzansky and modified by Kaban. The application of virtual surgical planning (VSP) to HFM, largely in children, is described and taken through to aspects indicated in maturity.

Results

VSP is demonstrated with clinical cases examples in HFM patients for (1) grafts and flaps replacing missing parts of the zygomatic bone, temporo-mandibular joint and mandible, (2) distraction osteogenesis for lengthening of the mandibular ramus, advancement of the mandibular body, widening of the face and simultaneous mid-face and mandibular rotation, (3) implants and correction of microtia for bone anchored ear prostheses, (4) correction of microtia by autogenous ear construction, and (5) end stage rotational bimaxillary osteotomies.

Conclusions

3D virtual and physical planning is a valuable adjunct to the treatment of this complex condition.
Genetic analysis, ultrasound phenotype, and pregnancy outcomes of fetuses with Xp22.33 or Yp11.32 microdeletions
Authors: Cai Meiying , Chen Xuemei , Li Ying , Lin Na , Huang Hailong , Xu Liangpu
Published: October 2023

Objectives

The phenotypes of Xp22.33 or Yp11.32 microdeletions comprising the short-stature homeobox (SHOX) gene have been extensively described in adults and children. Herein, the prenatal ultrasound phenotype and pregnancy outcomes of fetuses with Xp22.33/Yp11.32 microdeletions were analyzed to improve our understanding, diagnosis, and monitoring of this genetic condition in the fetal stage.

Methods

A total of 9,100 pregnant women referred to tertiary units for prenatal diagnosis were evaluated by chromosomal microarray analysis(CMA).

Results

Seven (0.08 %) fetuses had Xp22.33/Yp11.32 microdeletions, ranging from 243 kb to 1.1 Mb, that comprised SHOX. The ultrasonic phenotypes differed among these fetuses, with three fetuses presenting abnormal bone development, one had labial-palatal deformity and strawberry head, two had an abnormal ultrasonic soft marker, and one had no abnormalities. After genetic counseling, only one couple underwent pedigree assessment, which confirmed the paternal origin of the microdeletion. This infant presented delayed speech development, whereas other three infants showed a typical postnatal development. In three cases, the parents chose to terminate the pregnancy.

Conclusions

The ultrasonic phenotype of fetuses with Xp22.33/Yp11.32 microdeletions resulting in SHOX heterozygosity loss is variable. Prenatal CMA can quickly and effectively diagnose Xp22.33/Yp11.32 microdeletions and SHOX loss, which may help prenatal counseling.
Preparation and properties of a novel decorative base paper for formaldehyde-free adhesive impregnation
Authors: Liang Min , Gong Jingya , Xu Jianfeng , Liu Ru , Long Ling
Published: October 2023

Formaldehyde-free adhesives are gaining attention due to their compatibility with green production methods. Decorative base paper (DBP) is known for its physical strength and printability and has a high ability for absorbing aldehyde-free adhesives for impregnation. In this paper, DBP was prepared with TiO2 and SiO2 combined with polyvinyl alcohol (PVA), where the amount of TiO2 was reduced in the pulp process. The prepared DBP was impregnated by aldehyde-free adhesive and hot-pressed on wood-based panels. The results showed that upon SiO2 coating, the surface smoothness of base paper increased by 132.3 %, whereas the tensile strength increased by 33.6 %. Furthermore, the colour density of cyan, magenta, yellow and black colours increased by 75.4 %, 99.2 %, 51.9 % and 90.5 %, respectively. The surface properties like surface bonding strength and wear resistance of the covered wood-based panels were found to satisfy the standard requirements, which indicates the products can be used for furniture products.
Older Adults Catch Up to Younger Adults on Cognitive Tasks After Extended Training
Authors: Das Priyam , Steyvers Mark
Published: October 2023

Cognitive decline often accompanies natural aging, which results in younger adults outperforming older adults, on average, on cognitive tasks requiring skills such as attention, memory, or reasoning. This performance gap between age groups persists even after people train on these tasks, but it remains unclear whether the gap persists when individuals, rather than groups, are compared at different training levels. In this paper, we analyzed 9,923 users between 18-90 years old (63% over 60) who performed a variety of cognitive tasks on an online cognitive training platform. We quantified an older adult’s potential to catch up to, or perform as well as, a younger adult. We found that the probability of catching up to someone decades younger increases with differential amounts of training on a variety of cognitive tasks. These findings suggest that age-related performance deficits can be overcome with additional training.
Parochialism and Its Meanings in the Latin American Social Sciences: Experiments with Web of Science and SciELO
Authors: Carvalho Lucas , Brasil Antonio
Published: October 2023

In this article, we discuss parochialism in the social sciences (anthropology, political science, and sociology) via scientific indexing data. We take parochialism to mean the discussion of problems and themes related to the researchers’ national societies. To this end, we selected from the Web of Science and SciELO databases documents that have at least one author with institutional affiliation in the United States, Brazil, Argentina, Chile, or Mexico, from 2002 to 2021, totaling 175,821 documents. Based on scientometric techniques, text mining, and network analysis, we propose a multilevel approach to the topic of parochialism in the social sciences. The results point to close degrees of parochialism in all the selected national cases, varying in meaning according to the level of analysis (coauthorship, bigrams, and bibliographic references).
Tratamiento de defectos acetabulares tipo IIIA-B de Paprosky y discontinuidad pélvica con implantes 3D a medida: resultados a mediano plazo
Authors: Vega Carlos Alberto , Moruno Favio , Garavano Esteban , Sued Matías , Palomino Prado Ellery
Published: October 2023

Introducción: La revisión acetabular es una cirugía particularmente desafiante cuando hay pérdida de stock óseo y defectos acetabulares extensos. Los implantes 3D pueden suplir estos defectos y adaptarse a cada circunstancia. El objetivo de este estudio fue evaluar los resultados clínicos y radiográficos en pacientes con defectos acetabulares severos tratados con implantes impresos en 3D y determinar la constricción adecuada del cotilo para cada paciente.
Materiales y Métodos: Se realizó un estudio retrospectivo de 10 pacientes con defectos acetabulares severos clasificados como tipo IIIA-B de Paprosky y discontinuidad pélvica que se sometieron a una cirugía con prótesis acetabular a medida impresa en 3D, a cargo del mismo equipo quirúrgico, entre 2016 y 2022.
Resultados: El seguimiento medio fue de 40.5 meses. El puntaje de cadera de Harris mejoró significativamente de un promedio de 24,2 a 63,5 en el último control. No se observaron signos de aflojamiento ni migración del cotilo 3D en cuanto a la inclinación y anteversión en ningún caso, en el último control.
Conclusión: Los implantes acetabulares a medida representan una solución válida para tratar defectos óseos acetabulares severos y la discontinuidad pélvica.
“E aquele adeus não pude dar”: vivências de familiares enlutados pós-COVID-19
Authors: Damasceno Silva Walkerlane Adelaide , Agra Glenda , Neto Olavo Maurício De Souza , Pimentel Edlene Régis , Gouveia Bernadete de Lourdes André , Gaudêncio Edmundo De Oliveira
Published: October 2023

O luto é um processo complexo e é uma experiência singular, influenciada por fatores como concepções e crenças a respeito da natureza do morrer ou de uma morte pela relação que existia com a pessoa falecida, pelas circunstâncias nas quais ocorreu o falecimento, e por características próprias do enlutado. O objetivo geral deste estudo é investigar a vivência de familiares enlutados pela COVID-19. Trata-se de uma pesquisa exploratória, com abordagem qualitativa, que foi realizada com familiares enlutados da COVID-19 em um município da Paraíba. Participaram do estudo 20 familiares enlutados da COVID-19. Para analisar os dados foi adotada a técnica de Análise de Conteúdo de Bardin. A partir dos discursos dos familiares enlutados da COVID-19, foi possível construir três categorias temáticas, a saber: Categoria Temática 1 - Processo de comunicação durante a internação e pós-óbito; Categoria Temática 2 – Último adeus e Categoria Temática 3 - Rede de apoio psicossocial. Conclui-se que, o processo de comunicação aconteceu tanto de forma positiva, quanto negativa; que a ausência de um ritual de despedida embaraça e prolonga o processo de luto e que não houve apoio psicossicial por parte dos profissionais de saúde.
Milli Mücadele’deki Türk Zaferini İngilizler Nasıl İzah Ettiler?
Authors: SATAN Ali , DEDEOĞLU Bahtiyar
Published: October 2023

1.Dünya Savaşı’nda Osmanlı Devleti İtilaf Devletlerine karşı Almanya’nın yanında savaşa girmiş ve 30 Ekim 1918 tarihinde Mondros Mütarekesi ile mağlubiyeti kesinleşmiştir. İtilaf Devletleri, Paris Barış Konferansı’nda Yunanlıların İzmir’i işgal etmesine onay vermiş ve bu 15 Mayıs 1919 tarihinde bu işgal kanlı bir şekilde yapılmıştır. İtilaf Devletleri’nin Yunanlıları piyon olarak kullanması süreç içerisinde aralarında bir sorun haline gelmiştir. İngiltere, Fransa ve İtalya tarafından yalnız bırakılmıştır. İngiltere, Anadolu’da Yunanlıların tek destekleyicisi olarak kalmıştır. Yunanlıların askeri zayıflığı ve siyasi-ekonomik sıkıntıları, İngiltere’nin askeri ve ekonomik desteğinin sınırlı kalması, Ankara Hükümeti’nin askeri başarısını diplomasi ile taçlandırması Milli Mücadele’nin başarısını sağlamıştır. Bu çalışmada, dönemin İngiliz siyasi ve askeri aktörlerin Türk Zaferini nasıl açıkladıkları, hangi faktörleri öne çıkardığı kendi ifadeleriyle ortaya konacaktır. Ayrıca bu süreçte yaşanan fikir ayrılıklarına da dikkat çekilecektir.
Tevfik Rüştü (Aras) Bey’in Atina Telgraflarında Muhtelit Mübadele Komisyonu ve Faaliyetleri (1923-1924)
Authors: SARINAY Yusuf , KARACAKAYA Recep
Published: October 2023

On dokuzuncu yüzyılın sonlarında başlayan ve Osmanlı Devleti’nin son zamanlarında hızlanan kitlesel göçler, Birinci Dünya Savaşı sonunda kurulan yeni Türk devletinin de en önemli meselelerinden biri haline gelmiştir. 30 Ocak 1923 tarihinde Lozan’da “Türk-Yunan Nüfus Mübadelesi” sözleşmesi imzalanmıştır. Türkiye’de yaşayan Ortodoks Rum azınlık ile Yunanistan’da yaşayan Müslüman Türk azınlığın değişimi kararlaştırılmıştır. Bu sözleşmenin hükümlerini uygulaması için de Muhtelit Mübadele Komisyonu kurulmuştur.

Muhtelit Mübadele Komisyonu, karşılıklı göçü denetlemiş, kolaylaştırmış ve taşınır - taşınmaz malların tasfiyesi ile ilgilenmiştir. Mübadillerin bırakacakları mallara değer biçerek, bırakılan mala karşılık, borç tutarının yazılı olduğu belgeyi mübadile vermek gibi görevleri yerine getirmişlerdir. Türkiye ve Yunanistan’ın resmi temsilcileri olan komisyon üyeleri, bütün muhaceret işleri ile alâkadar olmuşlar, çalışmalarını daha etkin ve yerinden sürdürmek için Tali Komisyonlar kurmuşlardır.

Türk ve Yunan Nüfus Mübadelesine ilişkin oluşturulan Muhtelit Mübadele Komisyonu’nda Türkiye’yi Tevfik Rüştü (Aras) başkanlığında bir heyet temsil etmiştir. Komisyonun Atina’daki faaliyetleri sırasında, Tevfik Rüştü Bey sürekli olarak Ankara’ya komisyon toplantıları hakkında bilgi vermiş, tartışma konusu olan hususlarda Ankara’dan talimat beklemiştir. Tevfik Rüştü Bey, Yunanistan’daki Müslüman Türklerin, Türkiye’ye nakilleri esnasında, uğradıkları haksızlıkların giderilmesi ve mal ve mülklerinin mübadele sözleşmesine aykırı olarak ellerinden zorla alınması sürecinde, onların haklarını korumuş, bu konularda gerek komisyonun tarafsız üyeleriyle, gerek Yunan üyeleriyle ve gerekse Yunanistan Hükümeti yetkilileriyle büyük bir mücadele vermiştir. Konuyla ilgili olarak sürekli Ankara’ya, - çoğunlukla Başvekalete, bazen de Hariciye Vekaletine ve Mübadele, İmar ve İskan Vekaletine- ayrıntılı telgraflar göndermiştir.

Bu makalede, Muhtelit Mübadele Komisyonunun Türk Heyeti’nin reisi Tevfik Rüştü Bey’in, Atina’dan Ankara’ya gönderdiği telgraflar incelenmiş, mübadelenin gerçekleştiği dönemin bir kısmı değerlendirilmiştir.
VECTORS OF CULTURAL DEVELOPMENT OF SVERDLOVSK, 1940S – 1980S
Authors:   Institute of History and Archaeology,Ural Branch of Russian Academy of Sciences, Bugrov K. D. , Emeljanov E. P. ,   Ural Federal University
Published: October 2023

The paper examines the process of forming a cultural center of national level in Sverdlovsk, that is, a stable community of cultural actors working in one city and producing art which is measurably famous across throughout the country. The authors state that such cultural center arose in Sverdlovsk in the 1930s–1960s based on the acquired status of a “peripheral capital”, with Pavel P. Bazhov became the first Sverdlovsk literary figure possessing national popularity. Although local art and literary workers enjoyed certain popularity in the 1940s–1950s, it remained within a strict hierarchy of culture and was aimed at producing a “quasi-ethnic” Ural specificity. However, due to the socio-economic change of the 1960s, which led to the rapid growth of intelligentsia and bureaucracy (mainly in the fields of science, technology, planning, and projecting) in the city, Sverdlovsk cultural actors started to pursue innovative strategies, based on fashion, humanism, environmentalism, and historicism, to satisfy the growing non-market demand. Thus, in a planned economy, for the emergence of a national cultural center, not only stably funded cultural institutions were required, but also the presence of scientific and technical non-market demand, which would allow one to go beyond the strict hierarchy of cultural centers in a centralized Soviet system.
THE VIEWS OF RUSSIAN NATIONALISTS OF THE PERM PROVINCE DURING THE ELECTIONS TO THE IV STATE DUMA (BASED ON THE MATERIALS OF THE NEWSPAPER «PERMSKY VESTNIK»)
Authors:   National Research University “Higher School of Economics”, Glushkov A. V.
Published: October 2023

The All-Russian National Union, which combined both conservative and liberal features, remains one of the least studied parties that had a broad representation in the State Duma of the Russian Empire. In 1912, when the elections to the State Duma of the 4th convocation were held, the peak of activity of nationalists took place, which manifested itself in the opening of a number of their representative offices in provincial cities. Perm was no exception; however, practically nothing is known about the activities of the Perm National Society, founded in 1912. The only source that sheds light on the ideological attitudes of the Russian nationalists of the Perm province is the Permsky Vestnik newspaper, an election propaganda publication which existed from June to November 1912. The study of the newspaper publications of the Vestnik helps to determine the political affiliation of the Perm National Society and explains their clear success in the elections to the 4th State Duma, to which Perm nationalists immediately delegated 6 deputies out of 9. The members of the Perm National Society included prominent Perm public figures, officials, engineers, representatives of the church, such as V.A. Loschilov, Z.M. Blagonravov, A.A. Voskresensky, A.V. Zverev, I.N. Temnikov, A.N. Kuznetsov, and P.A. Ryabinin. An appeal to the Permskiy vestnik allows one to get an idea both about the views of a part of the Perm conservative camp, and about the methods of electoral struggle used during the period.
PRACTICES OF THE REVOLUTIONARY DUAL-PARTY SYSTEM: COALITION OF BOLSHEVIKS AND LEFT SRS IN THE AUTHORITIES OF MOSCOW AND MOSCOW REGION
Authors:   National Research University “Higher School of Economics”, Kontsevoy I. A.
Published: October 2023

The article examines the problem of interaction between the representatives of the Bolsheviks and the Left Socialist Revolutionaries in the institutions of Soviet power in Moscow and the Moscow region in the first half of 1918. The author introduces new archival documents into scientific circulation, which serve as an important source for studying the conflicts between the Bolsheviks and the Left SRs in Moscow government institutions. Using specific examples of ideological and administrative clashes, the author studies the practices of interaction between the Bolsheviks and the Left SRs within the framework of a dual-party coalition. The author proves that the interaction of representatives of the two parties in the Moscow authorities included both conflicts between the Bolshevik and the Left socialist revolutionary commissars, and joint state work, which consisted of organizing the management of the territory of Moscow and the Moscow region. Archival documents show that among the Bolsheviks there was no single point of view on the need for the existence of separate Moscow authorities. Representatives of the left communists, as well as the Left socialist revolutionaries, advocated the preservation of independent state institutions in the Moscow region, which created the possibility of an alliance between them and the Left Socialist Revolutionaries. However, the active actions of Vladimir Lenin prevented a split among the Moscow Bolsheviks. The emergence of a dual-party system in Soviet state institutions was a unique phenomenon in modern history of Russia, since representatives of the neo-populist socialist party could influence managerial decision-making. This situation led to the “power sharing” between the Bolsheviks and the Left SRs, which became a characteristic feature of the “long” revolution of 1917.
Crime Series of Modern Russia: a Criminological Analysis
Authors: Kleymenov Mikhail , Kleymenov Ivan
Published: October 2023

The authors provide a criminological view on series about criminals and those who should counteract them, which are broadcast in primetime and continue to be popular for a long time after their premiers. From the culturological standpoint, crime series in new Russia demonstrate an evident degradation, manifested in the glorification of those whom Fyodr M. Dostoyevsky called «murderers and prostitutes». The unceremonious crossing of the «red line» of moral prohibitions is highly meaningful - it represents the ideology of nihilism, permissiveness, and dehumanization of a person. A typical feature of Russian crime series is copying the West, and propaganda of Western club culture that is unimaginable without drugs. It is persistently impressed upon the viewers that drug-dealing business is protected by corrupt law enforcement officers. Crime series are often either explicitly or implicitly aimed at creating a negative image of law enforcement agencies: police officers do not only «protect» the business, but commit intentional crimes; prosecutors, as a rule, have close links with criminals, and customs officers - with smugglers. The negative picture presented by the series is aggravated by numerous legal blunders. Endless distortions of Russian legislation together with a typical readiness of servants of the law to violate it give some people the idea that vigilante justice and righteous revenge are admissible. The relative number of people sympathizing with the idea of vigilante justice is high and rather stable. It is an obvious symptom of the pathology of social organism indicating that the processes of the de-organization of legitimate power are under way. Some scholars assess such processes positively in their research, as manifestations of legal pluralism and community justice. It is an attempt to legalize the archaic forms of resolving conflicts in society. Modern experience of the break-up of states shows that when the state ceases to be the regulator of certain spheres of public life, its place is eventually taken by criminals. It is only possible to counteract this by strengthening the state power on the constitutional basis.
ALTERNATIVE ACCOMMODATION OF AN UNLAWFUL OCCUPIER’S CHOOSING: SOME REFLECTIONS ON Grobler v Phillips [2022] ZACC 32
Authors: Lerato Rudolph Ngwenyama
Published: October 2023

An abundance of case law dealing with eviction has emerged. Clear rules for evictions exist in the eviction context and a solid body of law is being developed in this regard. For many years, little attention was given to the issue of unlawful occupiers refusing to be evicted based on preferences or wishes to remain in the same house or land under the Prevention of Illegal Eviction From and Unlawful Occupation of Land Act 19 of 1998 (PIE). However, in recent years disputes around the choice of alternative accommodation in terms of the Extension of Security of Tenure Act 62 of 1997 (ESTA) have increased significantly.
Masson-Fontana Staining v1
Authors: not provided Nuriapenuelas
Published: October 2023

Masson-Fontana Staining for melanin detection
Home made direct RNA detection v1
Authors: Lee Hower , Grillo Marco , Nilsson Mats
Published: October 2023

Highly multiplexed spatial profiling of mRNAs has recently gained traction as a tool to explore cellular diversity, allowing to visualize the cell composition of tissues directly in-situ. We propose a sensitive, open-source, flexible and customisable method for the generation of in-situ expression maps of hundreds of genes. The method exploits direct ligation of padlock probes on their target mRNAs, coupled with rolling circle amplification and hybridization-based in situ combinatorial barcoding, to achieve high detection efficiency, high throughput and large multiplexing (up to few hundred genes).
Soil extract for cocultures host-parasites media v1
Authors: Culture Collection Roscoff , Bigeard Estelle , Guillou Laure
Published: October 2023

How to prepare soil extract
Troubleshooting guide for DDNS v1
Authors: Akello Joyce
Published: October 2023

This document provides general guidance for troubleshooting problems encountered in the DDNS method. It outlines the factors that might influence the outcome of the DDNS PCR assay run, the common problems encountered, possible causes of the problems, and provides recommendations on corrective action and preventative action. This document is primarily developed for DDNS performed on stool samples, but included are other factors to consider for other sample types.
Investigation of Secondary School Students' Area Measurement Knowledge and Skills
Authors: ÇAVUŞ ERDEM Zeynep
Published: October 2023

In this study, it is aimed to examine the area measurement knowledge and skills of secondary school students. In the study, in which the descriptive method was used, the data were collected in written form with 8 open-ended questions from 92 seventh grade students. Students' answers to open-ended questions were analyzed with a scoring scale. The research shows that the majority of students who correctly estimate the size of the area measurement units are in the majority, but they have difficulty in transforming the standard area measurement units. Students who can calculate the area as the number of unit squares covering a region are in the majority. It was observed that the students who were successful in measuring the area of the rectangle had low success in measuring the area of the parallelogram, triangle and trapezoid, and it was observed that the students tended to multiply the two sides of the polygon while measuring the area. In addition, it was determined that some students confused the area with the environment.
The Impact of Khan Academy Learning Platform on Mathematics Achievement in Primary School Fourth Grade Students
Authors: ULUM Hakan
Published: October 2023

This study aims to examine the effect of the Khan Academy learning platform on students' achievement in mathematics lessons. In the study, the difference between the achievement levels of the experimental and control groups was tested using a pre-test post-test control group design. The study group consists of primary school fourth grade students attending the support and training course. The study was conducted with a total of 60 students. The students in the experimental group were provided with mathematics course contents via the Khan Academy learning platform, and teaching was carried out using these contents. The students in the control group were taught mathematics with the Education Information Network (EBA). Firstly, a pre-test was applied to both groups, and the achievement levels of the students were recorded. Then, the Khan Academy learning platform was introduced to the students in the experimental group, and this platform was used in mathematics lessons. The students in the control group were introduced to EBA, and this platform was used in mathematics lessons. After a certain period of time, the post-test was applied to both groups, and the achievement levels of the students were measured again. The difference between the achievement levels of the experimental and control groups was statistically analyzed using the data obtained. As a result of this analysis, it was concluded that the Khan Academy learning platform had a greater effect on students' achievement in mathematics.
In the Light of Current Problems in Education: TÜBİTAK Science Child Magazine and Building a Sustainable Future
Authors: ŞAHİN Güliz , CENGİZ Tuğçenur
Published: October 2023

The aim of this study is to determine to what extent the texts in Bilim Çocuk (Science Child) magazine, which aim to contribute to the development of 21st-century skills, recognized as one of the current issues in education, and address the globally shared agenda of sustainable development goals, support the goals of sustainable development and contribute to the scientific development of children that they can utilize in their educational process. In this study, in which qualitative research design was utilized, the data were obtained through document analysis, and the data obtained were tabulated and interpreted with percentages and frequencies. In the selection of the magazines to be included in the study, 72 issues published in 2016-2021, determined by criterion sampling method, which is one of the purposeful sampling methods, were analyzed. According to the findings of the study, it was determined that 92.59% of the texts in Bilim Çocuk magazine belonged to the informative text type and 7.40% to the narrative text type, and that the texts in the magazine were related to "12. Responsible Production and Consumption" among the seventeen global goals the most (n=31) and the least (n=1) to "8. Decent Work and Economic Growth". It is recommended to include diversity in the types of texts in the journal and to include other goals that are not yet included in the context of raising awareness about sustainable development goals and encouraging individuals and institutions to take action.
Examining the Role and Perceived Importance of Video Experiments on Pre-service Teachers’ Understanding of Faraday’s Law in Online Learning Environment
Authors: KOCAKÜLAH Aysel
Published: October 2023

In this study, it was aimed to reveal the effect of teaching designed using real experiment videos on the development of university students' ideas about Faraday's law of induction and to determine the experiments that students considered most effective in their understanding of the induction phenomenon. The study was conducted online during the pandemic period with a sample of 52 first-year pre-service science teachers. The predict-observe-explain (POE) strategy was used in the teaching process and semi-structured interviews were conducted with nine students before and after the teaching. The interview data showed that the students had many scientifically unacceptable ideas about Faraday's law before the instruction, while these ideas were transformed into scientific truths after the designed instruction. In addition, it was tried to determine the experiment or experiments that students found most effective in understanding the subject after the instruction. Finally, it was concluded that teaching based on the POE strategy supported by real experiment videos used in online teaching was successful in remedying students’ unacceptable notions about electromagnetic induction and various suggestions were made in this regard.
Import Substitution of Information Systems based on the С# Language and Network
Authors:   V. A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, 117997, Russian Federation, Kurako E. A. , Asratian R. E. ,   V. A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, 117997, Russian Federation, Orlov V. L. ,   V. A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, 117997, Russian Federation
Published: October 2023

The purpose of the article is to study methods of migration to other environments of information systems previously created in Microsoft Windows in the C# language. These environments either belong to the open class, or were developed directly in Russia. One of the main migration tools is the separation of systems into components. In this case, the transformation tasks of each component are solved separately. Methods of transformation of information systems functioning in an environment based on operating systems, database management tools, web tools, frameworks and libraries are considered. The main directions of preparation of the executive environment, the components of which are included in the register of Russian software, or provide open source codes, are highlighted. Operating systems that meet the given criteria are selected. Basically, these systems are founded on Linux kernel. Methods for configuring the Apache 2 web server and creating a virtual host are defined. A brief assessment of database migration methods was carried out. The issues of correcting the C# source code when changing the operating environment and methods of converting the source text when changing the ways of working with the graphical user interface are considered. The main problems during the transition to the new system and ways to solve them are shown. Taking into account the mandatory code correction required during the migration process and the development of a new graphical user interface, the transition from Windows to Linux is possible at real time-consuming costs. Using existing methods of migrating databases, web services and client applications allows you to complete the migration of information systems based on the C# language into environments that meet the criteria for import substitution.
A Study of Existing Approaches to Transaction Analysis in the Bitcoin Network
Authors:   National Research Nuclear University MEphl, Moscow, 115409, Russian Federation, Basinya E. A. , Karapetyants N. ,   National Research Nuclear University MEphl, Moscow, 115409, Russian Federation, Karapetyants M. ,   National Research Nuclear University MEphl, Moscow, 115409, Russian Federation
Published: October 2023

Today, the Bitcoin network faces a number of challenges, such as flawed user identification and fraudulent transaction methods that are used by criminals to conduct illegal activities. As a result, there is a growing need to improve existing tools for tracking transactions, as well as to develop new methods for identifying money in the Bitcoin network. The paper presents a study and systematization of the subject area problems, and also considers possible approaches to neutralize it. The purpose of this work is to analyze the existing methods of transaction verification of the Bitcoin network. Within the framework of the work, a system architecture is proposed, which includes a comprehensive approach to the process of transaction analysis. Each of the stages of this process is described: information gathering, aggregation, processing and analysis. An extended set of empirical rules (heuristics) for transaction analysis, which are used in existing clustering methods, is considered. The results of this work will provide an opportunity to improve the existing Bitcoin transaction verification methods and develop a new one with the possibility of increasing the efficiency of the process of identification of illegally obtained funds and their sources.
Left ventricular noncompaction with ventricular aneurysm in a 6-year-old patient
Authors: Dautov Tairkhan B. , Kaliyev Bauyrzhan B. , Yerekesh Bibissara T.
Published: October 2023

Ventricular noncompaction is a rare type of cardiomyopathy often associated with a ventricular aneurysm. We present a clinical case of a 6-year-old female who arrived at our clinic complaining of physical exertion. Echocardiography revealed prominent trabeculations in the left ventricular wall and a lateral-basal part bulging out, indicating noncompaction of the left ventricular myocardium with an aneurysm. With a noncompacted-to-compacted myocardium ratio of 2.6, magnetic resonance imaging revealed the presence of noncompacted myocardium. It also revealed impaired left ventricular systolic function and a left ventricular aneurysm with myocardial scarring. Coronary angiography ruled out coronary artery disease. Therefore, myocardial scarring was caused by noncompacted myocardium microcirculatory disorder.
Settlement location and school size as determinants of subjective well-being and behavioral attitudes among adolescents
Authors: Chemerskoy Grigory S. , Tyulyupo Svetlana V. , Dashieva Bairma A.
Published: October 2023

BACKGROUND: Empirical data on the effect of infrastructural and geographical factors on the subjective well-being of residents of small urban and rural communities are scarce. AIM: To identify indicators of subjective well-being among adolescents, as well as their behavioral attitudes and subjective assessments of the school environment. MATERIAL AND METHODS: We analyzed data collected from 1164 respondents residing in 25 rural and urban settlements across Siberia and the European part of Northern Russia between 2016 and 2018. The Cronbachs alpha values for the dependent variables ranged from 0.654 to 0.811. The variables used to differentiate the comparison groups included the school size, the distance of the settlement from the regional centers infrastructure, and its geographic location in relation to the Arctic zone. RESULTS: Various characteristics of the school environment demonstrated the effect of differentiating variables. These characteristics included the friendliness within the school environment, the attitudes of teachers, the preparedness for self-defense, and the attitudes towards the use of psychoactive substances and illegal behavior. The attitudes towards the use of psychoactive substances and the readiness for self-defense were particularly sensitive to differentiating variables. CONCLUSION: The results of this study can be used to develop solutions that effectively manage the risks associated with the social and personal development of adolescents residing in small urban and rural settlements within sparsely populated regions of the Russian Federation.
The options of ultrasound biomicroscopy in the diagnosis of post-traumatic pathology of the anterior segment of the eyeball
Authors: Sobolev Nikolay P. , Uzunyan Dzhulietta  G. , Shkandina Yuliana V. , Teplovodskaya Viktoriia V. , Sudakova Ekaterina P.
Published: October 2023

BACKGROUND: In the literature, there are scarce publications on the use of ultrasound biomicroscopy in patients with post-traumatic changes in the anterior segment of the eyeball.
AIM: The aim of this study is to study the anatomical and topographic features of post-traumatic conditions of the anterior segment of the eyeball, to determine the criteria for the progression of the disease, to evaluate the possibilities of using the data obtained to determine the tactics of surgical treatment and of individual approach to the choice of implantable optical and diaphragmatic implants.
MATERIALS AND METHODS: The study is based on the analysis of the results of ultrasound biomicroscopy of 360 patients with the sequelae of traumatic injuries of the anterior segment of the eyeball. The patients were divided into groups depending on the nature and degree of damage to the iris. The IA group combined clinical cases where the iris defect was less than 30%; the IB group more than 30%.
RESULTS: Using ultrasound biomicroscopy, not only the zones of interest were visualized, but the anatomical relationship between the morphological structures of the anterior eye segment and the ciliary body was determined in vivo, their acoustic density was evaluated, and the necessary linear parameters of the eye were measured in the case of ordering and subsequent implantation of intraocular products.
CONCLUSIONS: Ultrasound biomicroscopy should be considered as an integral part of the diagnostic examination of patients at the stage of preparation for opto-reconstructive procedure.
Phacoemulsification with IOL implantation at a critical level of corneal endothelial cells
Authors: Loskutov Igor A. , Fedorova Anastasia I.
Published: October 2023

BACKGROUND: Cataract phacoemulsification is one of the most frequently performed surgical procedures, and a decrease in the corneal endothelial cell density (ECD) is the main postoperative complication leading to visual impairment. The average cell loss after phacoemulsification is 4.0112.94% within a year, and within 2 months 5.29.1%. The use of viscoelastics helps to reduce this loss, but it is impossible to completely prevent it.
AIM: Сomparison of ECD in the pre- and postoperative period of phacoemulsification using viscoelastic of different percentages at a critical level of corneal endothelial cells.
MATERIALS AND METHODS: The study included 60 eyes with emmetropic refraction: in the first group: 30 eyes with initial cataract and low ECD level (1694/1218 cells/mm2), an apyrogenic moderately cohesive viscoelastic 1.6% sodium hyaluronate solution (Kogevisk, Solopharm) was used, in the second group: 30 eyes with mature cataract and ECD level (1646/1183 cells/mm2) an apyrogenic, highly purified viscoelastic was used, consisting of medium-molecular fractions of chondroitin sodium sulfate 4% and sodium hyaluronate 3% (Adhevisk, Solopharm). Before surgery and a month after surgery, patients were tested for uncorrected visual acuity in the distance, ECD measurements, and intraocular pressure measurement.
RESULTS: In phacoemulsification with IOL implantation, the use of viscoelastics of different percentages shows that the condition of the cornea remained stable a month after surgery. Postoperative ECD loss in all clinical cases, regardless of the stage of cataract, was less than 3%.
CONCLUSIONS: Viscoelastics allow to solve the tasks set: in the case of cohesive maintaining the depth of the anterior chamber and the width of the pupil, adhesive protecting the corneal endothelium, good visualization. Rational consistent use of adhesive and cohesive components facilitates basic manipulations during phacoemulsification and IOL implantation. To do this, it is necessary to correctly use and select viscoelastic for a particular operation based on the number of endothelial cells.
Idiopathic omentum hemorrhage as a cause of hemoperitoneum
Authors: Ryazanov Vladimir V. , Sadykova Gulnaz K. , Zheleznyak Igor S. , Ipatov Victor V. , Khodkevich Ilya S. , Postanogov Roman A. , Romanov Gennadiy G. , Latysheva Anastasiya Ya.
Published: October 2023

Hemorrhage into the large omentum is a general term for a pathological condition in which an omental artery and/or vein ruptures with bleeding into the abdominal cavity and/or forming an omental hematoma. There is a high probability of its diagnosis only during surgery. This is an extremely rare condition, which is described only in clinical case reports. There are primary and secondary omental hemorrhage. Secondary hemorrhage occurs due to various reasons, primary (idiopathic) in the absence of morphological changes that could lead to bleeding to the large omentum. The article is devoted to a rare case of idiopathic omentum bleeding complicated by hemoperitoneum, diagnosed intraoperatively. The article presents the results of a literary review of the last twenty years on English-language and Russian-language publications on omental hemorrhage, presented in the databases of PubMed and the Russian scientific electronic library (eLIBRARY.RU). According to the results of the analysis of the literature data, ultrasound can be used as a first-line imaging method to assess the presence of hemoperitoneum. But CT angiography is the method of choice in assessing acute intra-abdominal bleeding and determining the cause of bleeding due to its speed, availability and ability to diagnose alternative causes of abdominal pain, and it is also recommended to be performed in cases where ultrasound data do not allow to unambiguously establish the presence of bleeding or localize its source. Also, taking into account the age characteristics and gender of patients, the presence of bleeding into the omentum may be due to conditions such as cystic lymphangioma and interrupted ectopic pregnancy. Other causes may be vascular pathologies, tumors and anticoagulant therapy. When detecting signs of bleeding into the large omentum, in addition to determining the fact of hemoperitoneum and its volume, the most important tasks are to establish the causes of hemorrhage and differential diagnosis between idiopathic and secondary bleeding.
Procedural aspects of admission to medical activity of persons who have received medical (pharmaceutical) education in the territories of the new subjects of the Russian Federation before September 30, 2022 and Ukraine
Authors: Kolenova Valeria V. , Shepeleva Julia L.
Published: October 2023

RELEVANCE: Study of peculiarities of authorization measures formed by the regulator to ensure the safety of medical services rendered to the population acquires particular relevance in view of the current geopolitical situation and the need for employment in the Russian Federation of citizens educated in foreign countries, including Luhansk and Donetsk Peoples Republics, Kherson and Zaporozhye regions, as well as Ukraine. The issue of admission of these medical (pharmaceutical) workers to carry out professional activities in the territories of the new subjects is also of interest.
OBJECTIVE OF THE STUDY: Based on the analysis of the normative-legal base of regulation of admission to medical (pharmaceutical) activities of specialists who received their professional education in the territory of foreign countries and republics of the former Union of Soviet Socialist Republics, to identify ways of implementing state guarantees of quality medical care and social guarantees to the population of the new regions of the Russian Federation, in terms of admission of these medical specialists to professional activities.
MATERIAL AND METHODS: By method of expert evaluations the analysis of normative base of the Russian Federation regulating legal relations of subjects at reception of admission to medical (pharmaceutical) activity in case of reception of professional education in foreign states and republics of the former USSR was carried out.
RESULTS: The normative-legal base of admission of the specialists, who got medical (pharmaceutical) education outside the territory of Russia, to professional activity, which was in force since 1995, provided in the part concerning the measures on rendering qualitative and safe medical aid to the population. Under the conditions that led to the accession of new subjects on September 30, 2022, the federal executive bodies involved in the admission of specialists with medical (pharmaceutical) education, obtained on the territory of new subjects of the country before their accession or in Ukraine, have adapted the existing order in the following ways: the allocation of these specialists in a group, for which a temporary order was developed, as well as optimization of time intervals for the implementation of a number of activities in obtaining admission to the new subjects of the country. These changes fully correspond to the state policy on support of new regions of the country and persons who arrived in Russia from the territory of Ukraine to improve the level of education and qualification of the personnel of the health care system.