bluuebunny/crossref_metadata_2025 huggingface dataset:
La masonería en la independencia de América
Authors: Soto Arango Diana Elvira , Puig Samper Miguel Ángel , Mora García José Pascual
Published: November 2023

Este libro presenta La masonería y su relación con la Independencia de los países americanos en diferentes facetas y controversias. A la fecha, no se ha llegado a un acuerdo sobre el papel real de la masonería en el proceso de emancipación americana, tanto a nivel continental como regional o nacional. Las razones son múltiples, desde las diferentes ópticas del historiador, la repetición de algunos tópicos establecidos históricamente sin validación documental y la confusión entre sociedades secretas de carácter político con la verdadera masonería. Es de esta manera que el libro da cuenta del debate entre las sociedades que promulgaron la independencia y los líderes de la revolución americana que fueron masones de manera individual o que se valieron de la masonería en algunos momentos de su vida, para lograr el objetivo de la independencia en esta región de la América Colonial.
Tango: danza de pies ligeros
Authors: Soledad Martha , Ricardo Esaú
Published: November 2023

Este libro se aventura a juntar los cuerpos, el baile y la música sobre el horizonte de experimentar, con el tango, la construcción de lazo social. Una pedagogía del movimiento en el que, sobre un mismo espacio dos cuerpos aprenden a caminar juntos. Sin palabras, sin códigos formales, en la sutilidad de una intención que se vuelve acto asimétrico en el movimiento en relación con los cuerpos, haciendo causa común en el ritmo y el tiempo, por el que se llega de frase en frase que coincide con la pieza musical y en la dirección del círculo que se cierra sobre la pista por el que una montonera baila como improvisara los pasos, como si improvisara el tiempo. Y es una improvisación
El astrolabio
Authors: Rodríguez Nana
Published: November 2023

El libro contiene una selección personal de piezas literarias reunidas en cuatro libros de cuentos, minificciones y minicuentos es un ejercicio no sólo para quien las escribe sino para los lectores y lectoras posibles. De esta manera, se puede observar cómo la escritura cambia, evoluciona y también conserva algunos riesgos personales.
Enseñanza del español para extranjeros a través de la cultura popular
Authors: Ramírez Avendaño Alberto , Rodríguez Pérez José Bernardino , Waked Hernández Myriam , Cárdenas Fonseca Pedro Leonidas
Published: November 2023

La obra selecciona, agrupa y adopta textos que pertenecen a la cultura popular colombiana, tales como mitos, leyendas y agüeros, los cuales ayudan al fortalecimiento del Español como Lengua Extranjera (ELE).
Lúdicas de enseñanza en producción y operaciones
Authors: Amaya González Luis Felipe , Carreño Dueña Diego Andrés , Ruiz Orjuela Erika Tatiana , Castillo González Jessica
Published: November 2023

El libro pretende ser el precursor de competencias para la toma decisiones en los futuros profesionales de Administración Industrial e Ingeniería Industrial, a partir del desarrollo de lúdicas de enseñanza de aprendizaje activo que representan situaciones de la vida real, permitiendo además la experiencia práctica de trabajo en equipo y convirtiéndose en un canal del hacer a lo teórico abordando temas propios del área de Producción de Operaciones
Matemáticas financieras
Authors: López Sánchez Lina , López Sánchez Mary Luz , Gómez Sanabria Eduardo
Published: November 2023

Este libro busca orientar al lector en las diferentes temáticas que cubren las matemáticas financieras y su aplicación a las NIIF, especialmente a los preparadores de información financiera de las pequeñas y medianas empresas (pymes), que conforman el Grupo 2, según lo establecido en la Ley 1314 de 2009 y el Decreto 3022 de 2013.  Es un valioso insumo para la toma de decisiones empresariales y un apoyo en los procesos de enseñanza y aprendizaje en el área contable y financiera. En el desarrollo del texto se incluye, además de los conceptos básicos e indicadores, la presentación de casos prácticos, los cuales involucran el uso de la matemática financiera articulada con los criterios de medición exigidos en las normas internacionales de información financiera, tanto para el reconocimiento inicial, como para el reconocimiento posterior.  Para hacer más comprensible el uso de esta guía, se incluye como herramienta de cálculo la aplicación Excel de Microsoft.
Conversación y convivencia
Authors: Agudelo Cely Nubia Cecilia , Estupiñan Quiñones Norman
Published: November 2023

Da cuenta de la participación de diversos actores con el propósito de indagar sobre comprensiones en relación con reservorios de conversación y convivencia en la escuela , particularmente en programas de formación complementaria de educadores en Escuelas Normales Superiores
Factores de éxito en la competitividad de destinos turísticos en Boyacá
Authors: Rodríguez Moreno Diana Cristina , Fonseca Sánchez Patricia
Published: November 2023

El sector turístico se ha convertido en fuente de desarrollo social y económico en comunidades de todo el planeta. Para el departamento de Boyacá, el turismo es un eje estratégico de desarrollo; este libro presenta Factores Críticos de Éxito para el Turismo en el departamento de Boyacá, determinados a través de revisión sistemática de literatura y priorizados mediante la consulta a expertos en turismo. Los factores de éxito priorizados para el turismo en Boyacá son el recurso humano, infraestructura vial, marketing de destino, políticas públicas, planificación del destino y sostenibilidad
Vive la joie en français
Authors: Pardo Segura Martha , Daza Hurtado Óscar Alejandro , Muñoz Talero Mary Luz
Published: November 2023

Ce matériel imprimé offre aux enseignants et aux écoles rurales Colombiens la possibilité de rendre  l´apprentissage du français à la postée des enfants. Ces élèves auront l´occasion de retenir plus aisément les nouveaux sons, les similitudes et les différences lexicales et grammaticales, la signifcation des mots et des expressions en français, en exploitant chaque activité pédagogique conçue et illustrée à la lumière du contexte propre. Le livre du professeur écrit en espagnol accompagne l'enseignement.
El año viejo
Authors: Salcedo Crescencio , Leonardo Omer
Published: November 2023

El libro está dirigido a músicos estudiantes y profesionales que deseen, en su práctica de conjuntos instrumentales, abordar repertorio colombiano en formato de ensamble de saxofones; además de servir como herramienta didáctica para docentes en la clase colectiva.
Marketing Dalam Manajemen Pendidikan Islam: Strategi Peningkatan Minat Masyarakat Terhadap Madrasah diMA Darussalam Kepahiang
Authors: Yanto Ari , Wanto Deri , Murniyanto Murniyanto
Published: November 2023

Persaingan ketat di era global mengharuskan sebuah lembaga pendidikan seaktif mungkin dalam memasarkan lembaganya untuk menarik minat peserta didik dan memperoleh kepercayaan masyarakat. Penelitian ini bertujuan untuk menelaah tentang Marketing dalam Manajemen Pendidikan Islam terkait Strategi Peningkatan Minat Masyarakat Terhadap Madrasah di MA Darussalam Kepahiang. Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif. Metode pengumpulan data menggunakan metode observasi, wawancara dan dokumentasi. Kemudian data diolah dengan tahapan analisis, reduksi, penyajian dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa Strategi Peningkatan Minat Masyarakat Terhadap Madrasah di MA Darussalam Kepahiang adalah dengan berupaya mengedepankan kolaborasi dan pendekatan masyarakat, pengembangan dan peningkatan mutu, tren dan program unggulan, pemasaran melalui media digital, biaya yang proporsional, dan menerapkan total quality management yang baik.
Program Induksi dan Supervisi Untuk Meningkatkan Kompentensi Guru Kota Salatiga
Authors: Laksono Kabul , Nisa Fakhrun , Rofi’ah Nur , Hariyadi Rahmat
Published: November 2023

Penelitian ini bertujuan untuk mendapatkan gambaran mendalam tentang program induksi dan supervisi yang diharapkan oleh guru di SMK Kota Salatiga. Penelitian ini menggunakan pendekatan survei dan instrumen yang digunakan adalah angket kuesioner. Penelitian dilakukan di beberapa SMK Kota Salatiga baik negeri maupun swasta. Hasil penelitian adalah bahwa sebagian besar guru mengharapkan adanya program induksi dan supervisi bagi guru pemula karena program tersebut belum terlaksana secara merata dan berkelanjutan pada beebrapa instansi pendidikan. Program induksi dan supervisi yang dilakukan meliputi perencanaan, pelaksanaan, dan evaluasi.
Strategi Manajemen Kurikulum dan Metode Pembelajaran Dalam Meningkatkan Prestasi Belajar Siswa di MTs Nashirul As’adiyah Pepara Tanah Grogot
Authors: Adiyono Adiyono , Agnia Ana Satia , Maulidah Tuhfah
Published: November 2023

Penelitian ini bertujuan untuk mengetahui strategi kurikulum dan metode pembelajaran di MTs Nashirul As’Adiyah pepara dalam meningkatkan prestasi belajar peserta didik. Penelitian ini menggunakan pendekatan kualitatif dengan pengumpulan data yang di peroleh melalui observasi, wawancara serta sumber lain berupa file/data. Sejauh ini proses strategi manajemen kurikulum sudah dilaksanakan sedemikian rupa dengan menerapkan perencanaan, pengorganisasian, pelaksanaan serta evaluasi di dalamnya. Dengan mengimplementasikan beberapa metode pembelajaran berupa ceramah, tanya jawab dan diskusi dengan menggunakan media sebagai penunjang terciptanya proses pembelajaran yang baik berupa lcd, alat peraga dan media visual dalam upaya peningkatan prestasi dalam diri peserta didik.
Analisis Kesesuaian Penyelenggaraan Perpustakaan Sekolah Berdasarkan Standar Perpustakaan (Studi Kasus MIS Bojongmalang Pangandaran)
Authors: Nukhbatillah Isyfi Agni , Hasanah Uswatun , Suhertin Tatin , Milah Ai Robihatil , Setia Mukti Ajeng Tanjiah
Published: November 2023

The library is one of the supporting components in an academic institution that plays an important role in providing books as a reference for learning. The function of the library itself is to provide services to users and increase reading enjoyment, as well as broaden the horizons and knowledge of students. The location of the MI Bojongmalang library is currently not strategic because it is in a hidden place, namely behind the school, near forests, gardens and now it is still in the renovation stage which has been neglected for a long time. the location is not strategic and seems haunted. The purpose of this research is to find out the ideal location of the school library building. This research is a qualitative research using observation, interviews and literature studies. The results of this study are that MIS Bojongmalang still requires continuous improvement and innovation efforts in the administration of libraries, especially in determining the location of library buildings and procuring shortages of other infrastructure facilities.
Past, current and future of legal regulation of drugs compounding in the Russian Federation
Authors: Mamedov D. D. , Yurochkin D. S. , Golant Z. M. , Fisenko V. S. , Alekhin A. V. , Narkevich I. A.
Published: November 2023

Today the activities of compounding pharmacies in terms of the drug compounding and in-pharmacy packaging of approval drugs is considered as a priority social task of the Russian Federation, due to the need to solve problems that are aimed at ensuring the strategic independence of the state from external and internal challenges, as well as threats, widespread introduction of personalized pharmacotherapy methods, opportunities in the field of optimizing the costs of the healthcare system.

The aim of the study was to conduct a historical analysis and comprehensive review of the current state of legal and regulatory framework of the Russian pharmaceutical market in the field of compounding drugs, as well as to develop proposals for improving the regulatory field.

Materials and methods. The following methodological tools – empirical, theoretical, quantitative ones – have been used in the work. In particular, an analysis of a wide range of relevant sources of information was carried out and information was obtained from legal and regulatory framework for the activities of compounding pharmacies in the Russian Federation, which was implemented using a bibliometric method of analysis.

Results. The main elements of the Russian legislation in the field of drug circulation with the aim of a comprehensive understanding of the classification and determination of the role of extemporaneous drugs in the Russian healthcare system, are presented in the article. A historical and technical analysis of the regulatory practice development is consistently presented. The key issues of organizing the pharmaceutical business in the field of compounding and dispensing of drugs on the territory of the Russian Federation have been considered, and current problems that need to be solved when improving the regulatory field, are presented.

Conclusion. The review conducted makes it possible to clarify further actions to improve federal legislation and delegated legislation in the field of circulation of compounded drugs by pharmacy organizations. The work presents recommendations that will contribute to the development of compounding pharmacies in the constituent entities of the Russian Federation.
Overview of drugs approved by the FDA in 2022
Authors: Kurkin D. V. , Morkovin E. I. , Bakulin D. A. , Gorbunova Yu. V. , Kolosov Yu. A. , Dzhavakhyan M. A. , Makarenko I. E. , Drai R. V. , Zaborovsky A. V. , Shatalova O. V. , Strygin A. V. , Petrov V. I. , Pleten A. P. , Prokopov A. A. , Tatarenko-Kozmina T. Yu.
Published: November 2023

The aim of the work is to conduct a review of medications approved by the FDA in 2022.

Materials and methods. In searching for the materials to write this review article, bibliographic databases including PubMed, Google Scholar and e-library.ru were utilized. The search was conducted for the publications spanning the period from 2008 to 2023. Herewith, the following keywords and word combinations were used: new drug approval, NDA, drug authorization, approval package, breakthrough medicine.

Results. The discovery and development of medications are among the most crucial scientific processes in healthcare. Developing a new drug is a highly intricate, expensive, and time-consuming process. Nowadays, the problem of costs reduction and the process of expedited discovering of new medications are particularly pertinent. To optimize the search for active compounds, virtual and high-throughput screenings, machine learning, artificial intelligence, cryo-electron microscopy, and drug repurposing are employed. Simultaneously, the search for original molecules to serve as the basis for innovative drugs continues. This article presents a review of medications approved by the FDA in 2022 for the treatment of various pathologies.

Conclusion. A drug development is a complex and resource-intensive process, with only a small fraction of candidates advancing to clinical trials. A drug design evolves in tandem with societal needs, and this review highlights some of the medications approved by the FDA in 2022. Technological advancements are expected to expedite drug development, potentially reducing the time to the market. Biotechnology, including cell therapy, holds significant prospects, and achievements in genetic mapping and chip technologies will enhance the accessibility of personalized pharmacology.
Russian development for drug independence in endocrinology: comparative analysis of bioequivalence, safety and tolerability of the first domestic liraglutide
Authors: Ametov A. S. , Shokhin I. E. , Rogozhina E. A. , Bodrova T. G. , Nevretdinova M. E. , Bely P. A. , Zaslavskaya K. Ya. , Kurkin D. V. , Koryanova K. N. , Mishchenko E. S. , Noskov S. M.
Published: November 2023

Liraglutide is one of the analogues of the incretin hormone human glucagon-like peptide-1 (GLP-1) and is currently a priority treatment for diseases such as type 2 diabetes mellitus (mono- and combination therapy), obesity and overweight in the presence of at least one concomitant disease.

The aim of the work was to assess the bioequivalence and comparability of the safety and tolerability profile of the drug Enligria® (liraglutide 6 mg/ml, Promomed RUS LLC, Russia) and the drug Saxenda® (liraglutide 6 mg/ml, Novo Nordisk AS, Denmark) after a single dose in healthy volunteers.

Materials and methods. This study was an open-label, randomized, crossover comparative study to evaluate pharmacokinetic parameters, safety, tolerability and immunogenicity. The study comprised 26 healthy volunteers, 26 of whom were included in the bioequivalence assessment population. The study consisted of 2 periods, in each of which the volunteers received either the test drug (liraglutide at a single dose of 0.6 mg) or the reference drug (liraglutide at a single dose of 0.6 mg) once. The washout period between each dose was 7 days. Blood plasma samples were taken to determine the concentration of liraglutide in the range from 0 to 72 hours in each study period. Liraglutide concentrations were determined using a previously validated enzyme-linked immunosorbent assay (ELISA) method. A quantitative determination of antibodies to liraglutide in the blood serum samples was carried out using a microplate photometer and ready-made ELISA kits pre-validated by the manufacturer. The conclusion about the equivalence of the compared drugs was made based on the ratio of the parameters Cmax, AUC0→t and AUC0→t of the studied drug in relation to the reference one.

Results. The pharmacokinetic parameters of the drugs were comparable to each other. The resulting 90% confidence intervals for the ratio of the values of Cmax, AUC0-t and AUC0-∞ of the Russian test and reference drug were 87.18–110.46, 84.40–104.11 and 86.69–103.22% respectively, which satisfied the criteria for assessing bioequivalence. The tolerability of the drugs in the volunteers was notified as good. The incidence of adverse events was comparable for the test and reference drugs. No serious adverse events were reported throughout the study. According to the results of the immunogenicity analysis, no antibodies to russian produced liraglutide were detected in the blood serum of the volunteers, which indicated the lack of the drug immunogenicity.

Conclusion. During the study, the pharmacokinetic equivalence of the test and reference drugs was confirmed. The Russian drug Enligria® (liraglutide 6 mg/ml, Promomed RUS LLC, Russia) in comparison with a foreign drug Saxenda® (liraglutide 6 mg/ml, Novo Nordisk AS, Denmark).
Adat Law and Legal Pluralism in Indonesia: Toward A New Perspective?
Authors: Hamida Nilna Aliyan
Published: November 2023

Adat law is part of Indonesia's legal system with unwritten characteristics. To some extent, it embeds with religious values. As a country with pluralist societies, adat law plays an important role in Indonesia that increasingly adds the critical discourse of legal pluralism since it originates from indigenous values based on habits to execute from the older generation. This study aimed to analyze the contextual development of adat law in Indonesia through a historical perspective and its applicability to its emerging positivization in the form of state law. It emphasized the recent development of transforming adat law into state regulation through by-laws with the following prospects and challenges. This study used socio-legal method research, a cross-disciplinary approach in nature through the form of analysis to the normative and contextual issues of adat law. This paper concluded that constituting the state regulation contains the boundaries to implement adat law as the right of adat community, adat court, and the adoption of the adat values. The positivization has developed by adopting adat law to by-laws at the regional level of governments. By-law is assumed to have law enforcement that binds the community because it comes from the habits of the community. Therefore, it indicates a new paradigm in recognizing and protecting adat law, not through by-laws, in which both adat and state laws are different and could not be a unity law.
KEYWORDS: Adat Law, State Law, Legal Pluralism, Indonesian Law.
Rights to Access of Public Facilities in Health Services for People with Disabilities
Authors: Dahlan Muhammad , Listiningrum Prischa , Wicaksana Dio Priagung
Published: November 2023

In Indonesia, the rights of people with disabilities (PwD) have not been fully fulfilled despite vigorous attempts to accommodate human rights for decades. Indeed, the Government has a commitment to fulfill the PwD rights in PwD Law 4/1997 and ratified the Convention on the Rights of Persons with Disabilities. In practice, the Government could not fully fulfill the PwD rights by providing facilities in the health sector. In this context, the Regency of Tulungagung has not set any regulations governing the fulfillment of the PwD rights. This study aimed to assess the PwD rights to access public facilities in health sectors in the Regency of Tulungagung, following factors that impeded the fulfillment of these rights. In doing so, the empirical method and socio-legal analysis probed a gap between law in book and context, elucidated in three main findings. First, the PwD rights in the Regency of Tulungagung to public facilities in health service sectors have not been fully fulfilled since public facilities are not PwD-friendly. Second, most health cares in this region have no staff capable of communicating and handling PwD. Third, the absence of the regulations governing the PwD rights becomes another factor leading to discrimination, coupled with the paucity of knowledge of how to interact with the PwD properly. Human resources and economic issues served as problems in this case. Most PwD in Tulungagung Regency lived in poor economic conditions due to a lack of available jobs that could be accessed. Therefore, the local government should take a more specific measure to fulfill public health access for PwD by allocating more budget, training the health care personnel, and enacting local regulations.
KEYWORDS: Human Rights, People with Disabilities, Public Facilities, Health Services.
Pendekatan Haptic Visuality pada Konstruksi Visual Film Burung Dara
Authors: Wasono Guntur Tri , Zamroni Muhammad , Aji Fajar
Published: November 2023

Eros love is one of love that is identic with the sensation of arousal and sexual desire in the pattern of teenage romance. The content of love that is attached to the emotions of actors and sensation of desire makes the author take on the major cinematographer in film Burung Dara. Burung Dara tells the story of a couple teenage who having relationship beyond the bounds of the norm.  The author uses a haptic visuality approach combined with emotional rhythm editing techniques to amplify emotions and give a touch-like sensation to the visuals of teenage love through a 27-minute film with a drama genre.
The Concept Promtoional Mix Max Pictures in Promotional Strategy Film Dilan 1991
Authors: Saputra Joshua Eka , Hartanto Denny Antyo , Astuti Soekma Yeni
Published: November 2023

Film distribution is an activity in the form of promotion with the aim to bring the film together with the audience. This is the basis of this research with the object of the film Dilan 1991. The problem of the research is how the concept of reference mix by Max Pictures in conducting the promotion strategy of the film Dilan 1991. The purpose of this research is to find out the concept of mixing reference by Max Pictures in conducting the film Dilan 1991 promotion strategy. This study uses qualitative research methods and theoretical approaches to marketing and promotion strategies. Data collection techniques used in this study were interviews with film Dilan 1991 producers and the film Dilan 1991 promotion team, observation of reporting on film Dilan 1991 in the mass media, and literature studies on marketing and promotion strategies. The results of this study are expected to be able to reveal how the concept of the promotional mix reference by Max Pictures in carrying out the promotion strategy of the film Dilan 1991. This research resulted in 2 discussions including a marketing strategy and a promotional mix reference in the film Dilan 1991.
Peran Mise En Scene dalam Mendukung Penciptaan Humor pada Film Milly & Mamet (Ini Bukan Cinta & Rangga)
Authors: Abdillah Sintia , Hartanto Denny Antyo , Kartika Bambang Aris
Published: November 2023

Film adalah bentuk karya seni berupa audio visual yang bertujuan untuk menghibur. Film bergenre komedi menjadi salah satu genre yang popular dikalangan masyarakat. Artikel ini membahas  mise en scene dalam mendukung penciptaan humor pada film Milly & Mamet (Ini Bukan Cinta & Rangga). Film Milly & Mamet (Ini Bukan Cinta & Rangga) merupakan salah satu film bergenre komedi popular yang disutradarai oleh Ernest Prakasa. Film ini mengangkat cerita kehidupan Milly & Mamet yang penuh drama komedi dari segi cerita maupun karakternya. Film Milly & Mamet (Ini Bukan Cinta & Rangga) memliki selera humor yang berkualitas ditunjukkan melalui karakter pemain, dialog dan adegan-adegan yang menggelitik penonton. Penelitian ini merupakan jenis penelitian kualitatif dengan menggunakan metode deskriptif. Hasil penelitian yaitu humor tercipta mengggunakan teknik-teknik penciptaan humor yang kemudian disampaikan secara verbal maupun visual. Aspek-aspek mise sen scene seperti setting, wardrobe, make up, dan pemain serta pergerakannya mampu menampilkan humor melalui visual sehingga membuktikan bahwa mise en scene memiliki peran dalam menciptakan humor pada film Milly & Mamet (Ini Bukan Cinta & Rangga).
Ahmatnijar: URGENSI PEMBAHARUAN DALAM IJTIHAD FIQH: TELAAH HISTORIS DAN MODEL IJTIHAD KONTEMPORER A
Authors: Nijar Ahmat
Published: November 2023

Abstract: The Prophet Muhammad SAW has already started the ijtihadpertice which is inspiring and do the regeneration to friend of the prophet.  Ijtihad as an Islamic law developmend mover machine goes with full of dynamics and always needs touch of renewal.
Ijtihad fiqh renewal deals  with a great struggle to rebuild arrange, recover the directions, mind set, or religious practice which involve real directing all obilities (bazl al-wus’i) to get practical syar’i through istinbath in facing contemporary dynamic challenge. This renewal must a futuristic ijtihad fiqh proces, not turn to a past  process through qiraat al-mukarrah and it is expected can decorate the reportoine of old civilizations. Istinbath  method which was applied was by combining nash text, sarwah fiqhiyah, , and ICT sistematically to bear an actual, futuristic, inspiring, and humanist fiqh fardli or  fiqh taqdiry
Supramolecular host-guest nanosystems for overcoming cancer drug resistance
Authors: Wu Sha , Yan Miaomiao , Liang Minghao , Yang Wenzhi , Chen Jingyu , Zhou Jiong
Published: November 2023

Cancer drug resistance has become one of the main challenges for the failure of chemotherapy, greatly limiting the selection and use of anticancer drugs and dashing the hopes of cancer patients. The emergence of supramolecular host-guest nanosystems has brought the field of supramolecular chemistry into the nanoworld, providing a potential solution to this challenge. Compared with conventional chemotherapeutic platforms, supramolecular host-guest nanosystems can reverse cancer drug resistance by increasing drug uptake, reducing drug efflux, activating drugs, and inhibiting DNA repair. Herein, we summarize the research progress of supramolecular host-guest nanosystems for overcoming cancer drug resistance and discuss the future research direction in this field. It is hoped that this review will provide more positive references for overcoming cancer drug resistance and promoting the development of supramolecular host-guest nanosystems.
Isoprenylated Flavonoids and 2-Arylbenzofurans from the Root Bark of Morus alba L. and Their Cytotoxic Activity of against HGC27 Cancer Cells
Authors: Pu Hang Yi , Cao Dong Yi , Zhou Xue , Li Fu , Wang Lun , Wang Ming Kui
Published: November 2023

Three new compounds (1, 11 and 12), together with 32 known ones, were isolated from the root bark of Morus alba L. using various chromatographic methods. The structures of the undescribed compounds were elucidated based on 1D, 2D NMR and HRESIMS data analysis, while the known ones were identified by comparison of their spectroscopic data with those reported in the literature. All the isolates were evaluated for their cytotoxic activities against human gastric cancer HGC27 cells by CCK-8 assay. Among them, compounds 5, 8, 10 and 30 exhibited cytotoxic activities on HGC27 cells with IC50 values of 10.24 ± 0.89 μM, 28.94 ± 0.72 μM, 6.08 ± 0.34 μM and 33.76 ± 2.64 μM, respectively. Furthermore, compound 10 was confirmed to reduce proliferation ability, increase apoptosis rate and inhibit cell migration pathway by annexin V/PI double staining experiment, transwell experiment and western blot analysis.
Probabilistic Assessment of Long-Span CFST Arch Bridges Based on Symmetrical Reliability Theory
Authors: Xie Zhujian , Dong Fenghui
Published: November 2023

The BP neural network and PSO algorithm are applied into analyzing the reliability of long-span Concrete Filled Steel Tubular (CFST) arch bridges. Firstly, using BP neural network to fit the structural performance function. And then the PSO method was used to calculate the reliability index. A long-span Concrete Filled Steel Tubular arch bridges reliability indices were calculated whether considering the geometric nonlinearity or not. The calculation and analysis results showed that the BP neural network and PSO algorithm compensated the deficiency of the traditional reliability analysis methods, improved the calculation accuracy, provided a new thought and means for the research on the reliability of long-span bridge structure, and well applied to the reliability analysis of long-span Concrete Filled Steel Tubular arch bridges. Additionally, the reliability analysis of long-span Concrete Filled Steel Tubular arch bridges on service limit state must consider the geometric nonlinearity effect, or the results will tend to be unsafe.
Rethinking Energy Conservation and Generation for Sustainable Solutions-An Innovative Energy Circuitry Approach
Authors: Kimuya Alex Mwololo
Published: November 2023

This paper presents an innovative energy circuit that challenges traditional notions of energy conservation, introducing a paradigm shift in classical settings. The quest to generate more energy in such settings has profound implications including, offering solutions to the global energy crisis, reducing environmental impact, and fostering scientific exploration. While addressing existing approaches that are hampered by misconceptions rooted in philosophical and scientific limitations, the paper contests the idea that something can be created from nothing, defying fundamental philosophical principles, and questions the reliance on perpetual motion machines as perfect models for impossibility. The paper introduces a unique circuit, originating from an anomalous electrical short circuit, that subverts traditional energy conservation laws. This energy circuit demonstrates merits that extend beyond traditional scientific boundaries, with applications ranging from enhancing electric vehicles with self-recharging capabilities to supporting microgrid development, efficiently incorporating renewable energy, and addressing the global energy crisis. Scientifically, the paper introduces a novel perspective, prompting a philosophical discourse on the dynamic nature of scientific inquiry. The provided energy circuit offers solutions to the global energy crisis by reducing dependence on finite resources, positioning it as a transformative technology for sustainable energy solutions. The energy circuit design aims to offer solutions to the global energy crisis by reducing dependence on finite resources, positioning it as a transformative technology for sustainable energy solutions. The paper concludes by demonstrating the circuit’s potential to transform energy systems and contribute to a more sustainable and resilient future.
Rethinking Energy Conservation and Generation for Sustainable Solutions-An Innovative Energy Circuitry Approach
Authors: Kimuya Alex Mwololo
Published: November 2023

This paper presents an innovative energy circuit that challenges traditional notions of energy conservation, introducing a paradigm shift in classical settings. The quest to generate more energy in such settings has profound implications including, offering solutions to the global energy crisis, reducing environmental impact, and fostering scientific exploration. While addressing existing approaches that are hampered by misconceptions rooted in philosophical and scientific limitations, the paper contests the idea that something can be created from nothing, defying fundamental philosophical principles, and questions the reliance on perpetual motion machines as perfect models for impossibility. The paper introduces a unique circuit, originating from an anomalous electrical short circuit, that subverts traditional energy conservation laws. This energy circuit demonstrates merits that extend beyond traditional scientific boundaries, with applications ranging from enhancing electric vehicles with self-recharging capabilities to supporting microgrid development, efficiently incorporating renewable energy, and addressing the global energy crisis. Scientifically, the paper introduces a novel perspective, prompting a philosophical discourse on the dynamic nature of scientific inquiry. The energy circuit design aims to offer solutions to the global energy crisis by reducing dependence on finite resources, positioning it as a transformative technology for sustainable energy solutions. The paper concludes by demonstrating the circuit’s potential to transform energy systems and contribute to a more sustainable and resilient future.
A Study on the Recovery of Valuable Metals from Solar Cells Using Acid Leaching and Substitution Reactions
Authors: Hyun Jong Kim , Urtnasan Erdenebold , Wang Jei-Pil
Published: November 2023

This study was conducted to recover valuable metals (silicon and silver) using acid leaching and substitution reactions with copper powder from the pulverized solar cell separated from the PV ribbon. Leaching experiments were conducted according to nitric acid concentration by molar solution as 1M, 2M, and 3M using an ultrasonic cleaner at a reaction temperature of 60 °C for the leaching times of 30 to 120 minutes. Si phases were detected at all leaching reaction times, it was confirmed that the aluminium was removed effectively if the nitric acid leaching time was more than 30 minutes, and silicon with a purity above 99% could be recovered. The silver was precipitated by adding copper, which has greater reducibility than Cu, Al, Si, Pb, and Sn. When the addition of copper powder was 0.75 and 1.0 g, precipitate was produced 0.23 and 0.55 g, respectively. The optimal condition for the recovery of silver by the addition of copper powder was 1 g, where is recovery rate reached 93.3%.
Diagnosis of Multiple Open-Circuit Faults in Three phase Induction Machine Drive Systems Based on Bidirectional Long Short-Term Memory Algorithm
Authors: Gmati Badii , Ben Rhouma Amine , Meddeb Houda , Khojet El Khil Sejir
Published: November 2023

Availability and continuous operation under critical conditions are very important in electric machine drive systems. However, such systems, are suffering from several type of failures that affect the electric machine or the associated voltage source inverter. Therefore, fault diagnosis and fault tolerance are highly required. This paper presents a new robust deep learning-based approach to diagnosis multiple open-circuit fault in three phase two level voltage source inverter for induction motor drive applications. The proposed approach uses fault diagnosis variables obtained from sigmoid transformation of the motor stator currents. The open-circuit fault diagnosis variables are then introduced to a Bidirectional Long Short-Term Memory algorithm to detect the faulty switch(es). Several simulation and experimental results are presented to show the proposed fault diagnosis algorithm effectiveness and robustness.
State data security backed by Artificial Intelligence and Zero Knowledge Proofs in the context of sanctions and economic pressure
Authors:   GOTBIT CONSULTING LLC, USA, Jalili Abdul Qawi , Dziatkovskii Anton ,   Platinum VC & Incubator Australia
Published: November 2023

This research paper aims to elucidate the intricate relationship between artificial intelligence (AI), state data security, and the volatile circumstances induced by sanctions and economic pressure. By undertaking a comprehensive literature review, the study not only offers a historical context of state data security mechanisms but also delves deeply into the advancements provided by AI-driven solutions. The work serves as a crucial reference for policymakers, cybersecurity experts, and academic researchers, laying a foundation for the nuanced understanding of AI’s capabilities and limitations within the realms of state data security and economic stressors. Employing an analytical framework, the paper systematically distills knowledge from a wide array of sources, including academic articles, technical reports, policy briefs, and international standards. This multidimensional analysis allows for a holistic understanding of the state-of-the-art AI technologies, their applicability in fortifying state data security, and the ethical labyrinth that states must navigate. Paper underscores a multitude of challenges and ethical considerations that are often overshadowed by the technological prowess of AI. These encompass issues such as data privacy infringement, potential for mass surveillance, and ethical quandaries around bias and discrimination. The paper also throws light on the pivotal factors of accountability and transparency, essential for maintaining public trust in AI-augmented state security mechanisms. The study raises awareness about AI-driven cyber threats, focusing on the paradox of employing AI to enhance security while also becoming susceptible to advanced AI-driven cyberattacks. Paper addresses the long-term sustainability and resilience of AI-enabled security measures, particularly in the context of evolving cyber threats and the inherent instability brought about by economic pressures and sanctions. The resilience of AI algorithms and systems under these specific conditions is scrutinized, offering a forward-looking perspective on the adaptability and robustness of AI technologies in safeguarding state data.
Hip Morphology on Post-Reduction MRI Predicts Residual Dysplasia 10 Years After Open or Closed Reduction
Authors: Schmaranzer Florian , Justo Pedro , Kallini Jennifer R. , Ferrer Mariana G. , Miller Patricia , Bixby Sarah D. , Novais Eduardo N.
Published: November 2023

Background:

There is limited evidence supporting the value of morphological parameters on post-reduction magnetic resonance imaging (MRI) to predict long-term residual acetabular dysplasia (RAD) after closed or open reduction for the treatment of developmental dysplasia of the hip (DDH).

Methods:

We performed a retrospective study of 42 patients (47 hips) undergoing open or closed reduction with a minimum 10 years of follow-up; 39 (83%) of the hips were in female patients, and the median age at reduction was 6.3 months (interquartile range [IQR], 3.3 to 8.9 months). RAD was defined as additional surgery with an acetabular index >2 standard deviations above the age- and sex-specific population-based mean value or Severin classification grade of >2 at last follow-up. Acetabular version and depth-width ratio, coronal and axial femoroacetabular distance, cartilaginous and osseous acetabular indices, transverse ligament thickness, and the thickness of the medial and lateral (limbus) acetabular cartilage were measured on post-reduction MRI.

Results:

At the time of final follow-up, 24 (51%) of the hips had no RAD; 23 (49%) reached a failure end point at a median of 11.4 years (IQR, 7.6 to 15.4 years). Most post-reduction MRI measurements, with the exception of the cartilaginous acetabular index, revealed a significant distinction between the group with RAD and the group with no RAD when mean values were compared. The coronal femoroacetabular distance (area under the receiver operating characteristic curve [AUC], 0.95; 95% confidence interval [CI], 0.90 to 1.00), with a 5-mm cutoff, and limbus thickness (AUC, 0.91; 95% CI, 0.83 to 0.99), with a 4-mm cutoff, had the highest discriminatory ability. A 5-mm cutoff for the coronal femoroacetabular distance produced 96% sensitivity (95% CI, 78% to 100%), 83% specificity (95% CI, 63% to 95%), 85% positive predictive value (95% CI, 65% to 96%), and 95% negative predictive value (95% CI, 76% to 100%). A 4-mm cutoff for limbus thickness had 96% sensitivity (95% CI, 78% to 100%), 63% specificity (95% CI, 41% to 81%), 71% positive predictive value (95% CI, 52% to 86%), and 94% negative predictive value (95% CI, 70% to 100%).

Conclusions:

Coronal femoroacetabular distance, a quantitative metric assessing a reduction’s concentricity, and limbus thickness, a quantitative metric assessing the acetabulum’s cartilaginous component, help to predict hips that will have RAD in the long term after closed or open reduction.

Level of Evidence:

Diagnostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
La nota del códice de Roda sobre el obispo Osio y el monje Ozim
Authors: GONZÁLEZ MUÑOZ Fernando
Published: November 2023

El propósito de este estudio es comentar desde diferentes puntos de vista la nota sobre el obispo Osio y el monje Ozim (Tultusceptrum de libro domini Metobii) contenida en el códice de Roda (Madrid, Real Academia de la Historia 78, f. 185v). Se señala especialmente su relación con otros textos hispanos de polémica contra el islam, el origen y sentido de la tradición que vincula al profeta Muḥammad con el obispo Osio y la pervivencia de esta leyenda en la posteridad. Se concluye que el texto debe entenderse ante todo como un apólogo que previene a los cristianos sobre los efectos del rito de conversión al islam.
Perifrasi verbali con εἰμί più participio nelle varianti del Pentateuco dei LXX
Authors: PIERRI Rosario
Published: November 2023

Nell’articolo sono raccolte e discusse le varianti con εἰμί più participio individuate nei testimoni della tradizione testuale del Pentateuco dei LXX; sono considerate anche le varianti con γίνομαι ma solo quelle concerneti il predicato nominale. La finalità è di osservare se vi siano tracce dell’affermazione della perifrasi nelle varianti, eventuali concentrazioni di frequenza insieme a sfumature d’uso, con particolare attenzione alla datazione dei testimoni dove appaiono. Un paragrafo è riservato anche alle varianti di costruzioni con predicato nominale (copula + aggettivo) rispetto a un verbo finito.
La divina substancia como māsūra y muftaraqa. Un intento de reinterpretación de la terminología trinitaria de acuerdo con la enseñanza de al-Risāla fī l-thālūth al-muqaddas de Abū Rā’iṭa
Authors: SADOWSKI Michal
Published: November 2023

Este artículo trata de la terminología trinitaria de Abū Rā’iṭa contenida en su al-Risāla fi l-thālūth al-muqaddas. Concretamente, se centra en una expresión que simboliza la unidad de la sustancia divina y la multiplicidad de hipóstasis, es decir “māsūra y muftaraqa”. Ofrecemos un intento de reinterpretación del significado de estos términos clave de acuerdo con la comprensión de la doctrina trinitaria de Abū Rā’iṭa.
Der Personenname „Mozaraber“ im Toledo des 12./13. Jahrhunderts. Prosopographische Bemerkungen zu den Trägern eines rätselhaften Namens
Authors: SAßENSCHEIDT Christian
Published: November 2023

En este artículo utilizamos un método prosopográfico para explorar el entorno socioeconómico de las personas que eligieron el término ‘mozárabe’ como nombre personal en el Toledo altomedieval. Consciente de las particularidades de la variedad árabe andalusí, este análisis incluye asimismo grafías de fonación similar que se desvían de la forma estándar musta‘rib. En tres casos el material fuentístico permite la reconstrucción de una parte considerable de los antecedentes familiares y económicos.
The Martyrdom of Arianos and the Four Protectores in an Unpublished Christian Palestinian Aramaic Palimpsest, St Catherine Monastery (Sinai, Arabic NF 66)
Authors: MÜLLER-KESSLER Christa
Published: November 2023

Entre los Nuevos Hallazgos en un almacén del Monasterio de Santa Catalina en 1975 vieron la luz una serie de palimpsestos arameos cristianos palestinenses. Algunos de ellos recogen historias de mártires rara vez atestiguadas, y en un caso los testimonios del texto griego están perdidos. Dos fragmentos contienen el martirio de Ariano y los Cuatro Protectores.
El diablo negro: el adjetivo μέλας en la Septuaginta, Nuevo Testamento, Epístola de Bernabé y el Pastor de Hermas
Authors: BROTÓNS MERINO María José
Published: November 2023

En la Literatura cristiana primitiva, particularmente en la Epístola de Bernabé (4:10 y 20:1), el Diablo es denominado ὁ Μέλας, apelativo traducido como “el Negro”. Una reflexión permite buscar el origen del vínculo entre negro y diablo en la literatura anterior: primeramente en la literatura griega, donde encontramos un uso ambiguo de μέλας, y en segundo lugar en la Biblia, ya que la Epístola de Bernabé está escrita en un contexto cristiano. Sin embargo, en la connotación negativa de μέλας en la Septuaginta no está clara, y es en el Nuevo Testamento donde el estudio debe extenderse a σκότος (“oscuridad”), para encontrar una relación directa con el diablo.
Homère chez Eustathe de Thessalonique : la traduction des Proèmes sur l’Iliade et l’Odyssée
Authors: KOLOVOU Georgia E.
Published: November 2023

In the present contribution, we present the translation of the Proems on Odyssey and Iliad of the Byzantize scholar of the 12th century Eustathius of Thessalonica. Firstly, we integrate these texts into the ensemble of the philological works of the erudite Byzantine and we show how the commentary on the Odyssey can be read in relation to the commentary on the Iliad. In the second part, we translate in French his Proems where Eusthathius explains himself the particular method of his compilative, autonomous and highly personal commentary on Homer.
Sacred & Pseudepigrapha Writings Symposium ‎‎(SPWI)‎ Textual Culture in Jewish and Christian ‎Intellectual Circles ‎‎
Authors: Luis Cobreros Goretti
Published: November 2023

Congreso internacional celebrado en  la Facultad de Filosofía y Letras de la Universidad de Córdoba el ‎3 de diciembre de 2018
Arabic Gospel Lectionaries at Sinai
Authors: Turnbull Robert
Published: November 2023

Recent studies grouping Arabic Gospel manuscripts into families by Valentin (2003) and Kashouh (2012) have excluded lectionaries. This restriction in scope is understandable but it means that the use of these translations in Arabic Christian worship remains to be explored. A full study of all the surviving Arabic Gospel lectionaries is clearly desirable. This study seeks to provide a small step in that direction by grouping the Arabic Gospel lectionaries currently held at St. Catherine’s monastery at Sinai into their own families according to their types and textual affinities. Twelve distinct families are distinguished and in many instances their sources from families of continuous-text Arabic Gospel manuscripts are identified.
Misión y educación: influencia occidental y cristiana en la China de los últimos años de la dinastía Qing y durante la República China (1912-1949)
Authors: Magdalena Mironesko Alexandra
Published: November 2023

Siendo China un país milenario no ha permanecido ajena a la influencia de otras naciones. Especialmente se destaca la importancia de los modelos educativos extranjeros en China, particularmente en un periodo de cambios y modernización. Sin embargo, poca es la información que hay del impacto de un grupo concreto de occidentales en la educación china, y es el de los cristianos y su labor en el país. Como misioneros, empezarían con una labor puramente evangelizadora, pero con los siglos adoptarían un acercamiento más diplomático y pragmático, mediante la fundación de escuelas y promoviendo la educación en China. De este modo, durante el periodo de la dinastía Qing, la última antes de pasar a la República, los misioneros cristianos asentaron unas bases de relevante importancia para la posterior modernización de la educación china.