bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of supplemental oxygen on systemic and cerebral hemodynamics in experimental hypovolemia: Protocol for a randomized, double blinded crossover study
Authors: Lindvåg Lie Sole , Hisdal Jonny , Rehn Marius , Høiseth Lars Øivind
Published: June 2022

Supplemental oxygen is widely administered in trauma patients, often leading to hyperoxia. However, the clinical evidence for providing supplemental oxygen in all trauma patients is scarce, and hyperoxia has been found to increase mortality in some patient populations. Hypovolemia is a common finding in trauma patients, which affects many hemodynamic parameters, but little is known about how supplemental oxygen affects systemic and cerebral hemodynamics during hypovolemia. We therefore plan to conduct an experimental, randomized, double blinded crossover study to investigate the effect of 100% oxygen compared to room air delivered by a face mask with reservoir on systemic and cerebral hemodynamics during simulated hypovolemia in the lower body negative pressure model in 15 healthy volunteers. We will measure cardiac output, stroke volume, blood pressure, middle cerebral artery velocity and tolerance to hypovolemia continuously in all subjects at two visits to investigate whether oxygen affects the cardiovascular response to simulated hypovolemia. The effect of oxygen on the outcome variables will be analyzed with mixed linear regression.

Trial registration: The study is registered in the European Union Drug Regulating Authorities Clinical Trials Database (EudraCT, registration number 2021-003238-35).
Chlorophyll decomposition is accelerated in banana leaves after the long-term magnesium deficiency according to transcriptome analysis
Authors: Kan Baolin , Yang Yong , Du Pengmeng , Li Xinping , Lai Wenjie , Hu Haiyan
Published: June 2022

Magnesium (Mg) is an essential macronutrient for plant growth and development. Physiological and transcriptome analyses were conducted to elucidate the adaptive mechanisms to long-term Mg deficiency (MD) in banana seedlings at the 6-leaf stage. Banana seedlings were irrigated with a Mg-free nutrient solution for 42 days, and a mock control was treated with an optimum Mg supply. Leaf edge chlorosis was observed on the 9th leaf, which gradually turned yellow from the edge to the interior region. Accordingly, the total chlorophyll content was reduced by 47.1%, 47.4%, and 53.8% in the interior, center and edge regions, respectively, and the net photosynthetic rate was significantly decreased in the 9th leaf. Transcriptome analysis revealed that MD induced 9,314, 7,425 and 5,716 differentially expressed genes (DEGs) in the interior, center and edge regions, respectively. Of these, the chlorophyll metabolism pathway was preferentially enriched according to Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. The expression levels of the five candidate genes in leaves were consistent with what is expected during chlorophyll metabolism. Our results suggest that changes in the expression of genes related to chlorophyll synthesis and decomposition result in the yellowing of banana seedling leaves, and these results are helpful for understanding the banana response mechanism to long-term MD.
Menstrual cycle changes and mental health states of women hospitalized due to COVID-19
Authors: Muharam R. , Agiananda Feranindhya , Budiman Yuri Fitri , Harahap Juliana Sari , Prabowo Kevin Ardito , Azyati Mazaya , Putri Yuannita Ika , Pratama Gita , Sumapraja Kanadi
Published: June 2022

Purpose

Many studies have evaluated the impact of the COVID-19 pandemic on women’s mental health and menstrual changes. However, most of these studies only included nonhospitalized COVID-19 patients, while information on hospitalized women is very limited. Thus, this study aimed to examine the mental health status and menstrual changes in hospitalized female COVID-19 patients.

Methods

A survey was administered to female COVID-19 patients in the isolation ward of a national referral hospital in Indonesia between January and August 2021, and the women were followed up 3 months after discharge. The survey evaluated menstrual patterns and mental health using the Self Reporting Questionnaire-29 (SRQ-29).

Results

The study enrolled 158 female patients. There was an increase in patients who had a cycle length of > 32 or < 24 days, and significant increases in menstrual irregularity and heavy menstrual bleeding were noted. Overall, 37.3% of the patients reported a change in menstrual pattern after infection with COVID-19. Based on SRQ-29 scores, 32.3% of the women had neurotic symptoms, 12.7% had psychotic symptoms, and 38.0% had symptoms of posttraumatic stress disorder. Patients with symptoms of mental health disorders were twice as likely to report a menstrual change (OR 2.17, 95% CI 1.12–4.22; p = 0.021).

Conclusion

Menstrual changes and increased symptoms of mental health disorders occur in hospitalized female COVID-19 patients. The length of isolation was the key factor affecting overall menstrual changes and mental health in hospitalized female COVID-19 patients.
HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells
Authors: Fittje Pia , Hœlzemer Angelique , Garcia-Beltran Wilfredo F. , Vollmers Sarah , Niehrs Annika , Hagemann Kerri , Martrus Glòria , Körner Christian , Kirchhoff Frank , Sauter Daniel , Altfeld Marcus
Published: June 2022

Antiviral NK cell activity is regulated through the interaction of activating and inhibitory NK cell receptors with their ligands on infected cells. HLA class I molecules serve as ligands for most killer cell immunoglobulin-like receptors (KIRs), but no HLA class I ligands for the inhibitory NK cell receptor KIR2DL5 have been identified to date. Using a NK cell receptor/ligand screening approach, we observed no strong binding of KIR2DL5 to HLA class I or class II molecules, but confirmed that KIR2DL5 binds to the poliovirus receptor (PVR, CD155). Functional studies using primary human NK cells revealed a significantly decreased degranulation of KIR2DL5+NK cells in response to CD155-expressing target cells. We subsequently investigated the role of KIR2DL5/CD155 interactions in HIV-1 infection, and showed that multiple HIV-1 strains significantly decreased CD155 expression levels on HIV-1-infected primary human CD4+T cells via a Nef-dependent mechanism. Co-culture of NK cells with HIV-1-infected CD4+T cells revealed enhanced anti-viral activity of KIR2DL5+NK cells against wild-type versus Nef-deficient viruses, indicating that HIV-1-mediated downregulation of CD155 renders infected cells more susceptible to recognition by KIR2DL5+NK cells. These data show that CD155 suppresses the antiviral activity of KIR2DL5+NK cells and is downmodulated by HIV-1 Nef protein as potential trade-off counteracting activating NK cell ligands, demonstrating the ability of NK cells to counteract immune escape mechanisms employed by HIV-1.
Study of Oligohydramnios and Perinatal Outcome in Term Pregnancy
Authors: Naseema Beevi  , Sona Venugopal  , Smitha Sreenivas  , Shaheem
Published: June 2022

BACKGROUND

Oligohydramnios is associated with an increased risk of adverse pregnancy outcomes. The perinatal mortality rate in oligohydramnios is high. Oligohydramnios is also associated with fetal heart conduction abnormalities, meconium staining of the amniotic fluid, umbilical cord compression, lower Apgar scores, poor tolerance of labour and fetal acidosis. We wanted to assess the perinatal outcome in term pregnancies complicated with oligohydramnios in this study.

METHODS

A prospective cohort study was conducted among 200 cases of pregnant women with singleton term pregnancy with intact membranes and AFI < 5cm admitted from January 2019 to June 2020 in the Department of Obstetrics and Gynaecology, Government Medical College, Kozhikode. Antenatal patients with oligohydramnios confirmed by USG were induced within 24 hrs based on the Bishops score. History and examination findings were recorded in a predesigned proforma. Mode of delivery and APGAR scores were also noted. Neonatal complications and the need for ICU admission were studied up until their NICU admission or hospital stay.

Statistical Analysis: Statistical tests of association using SPSS (version 20.0) were employed at the level of significance of 5 %.

RESULTS

The majority of patients in this study were primigravida (60.5 %) and belonged to the age group 20-29 yrs (73.5 %). There was a higher rate of induction (67.5 %) in oligohydramnios patients. Around 26 % had meconium-stained amniotic fluid. The rate of caesarean section was found to be 22.5 % and that of instrumental delivery was 3.5 %. Oligohydramnios was associated with a higher rate of NICU admission (27.5 %). The most common complications noted were jaundice (9.8 %), birth asphyxia (4.9 %), meconium aspiration syndrome (3.4 %) and respiratory distress syndrome (1 %). Only 1 case of neonatal mortality was seen in this study.

CONCLUSIONS

Oligohydramnios adversely affects the maternal and perinatal outcome. It is associated with higher rates of induction, caesarean section, meconium-stained amniotic fluid, low APGAR scores, fetal distress and perinatal morbidity and mortality. However, the outcome can be improved by good antepartum and intrapartum monitoring and neonatal care.
A Study of Pregnancy in a Non-Communicating Rudimentary Horn of the Uterus
Authors: Dhruva Somashekhar Patil  , Manisha Manish Laddad  , Somashekhar Veerangouda Patil
Published: June 2022

BACKGROUND

Pregnancy in a non-communicating horn of the uterus is a very rare entity. Incidentally, we had 11 cases in the last 6 years presenting in various ways. In literature, cases presented on pregnancy in a non-communicating horn are not many. Hence we are analysing our cases. The objectives of our study were to diagnose and manage such cases at the earliest and sharing our experience to help for its early diagnosis and further management.

METHODS

Records of women diagnosed with ectopic pregnancy in the rudimentary horn, during the last 6 years, were reviewed for their diagnostic difficulties and the associated morbidity.

RESULTS

Cases diagnosed before laparotomy were 3, and cases diagnosed after laparotomy were 8. Amongst 8 cases, 2 were intact and the other 6 had already ruptured. Laparotomy with excision of rudimentary horn and salpingectomy was done in all cases.

CONCLUSIONS

Suspicion is the main tool for diagnosis. Its suspicion and clinical finding along with imaging technology are very important for its early diagnosis and management.
Assessment of Knowledge of Emergency Management of Ocular Trauma in a Tertiary Care Hospital
Authors: Angela Edith  , Nitin Batra  , Rohan Kapoor
Published: June 2022

BACKGROUND

Ocular trauma is a major cause of preventable monocular blindness and visual impairment worldwide. Thorough knowledge of comprehensive management of all types of ocular trauma is of utmost importance in the visual prognosis of such patients. Nurses are an integral part of emergency care. The objectives of this study were to assess the knowledge of emergency management of ocular trauma among the nursing staff and final year B.Sc. nursing students at a tertiary care hospital in northern India and suggest methods to enhance the knowledge if required.

METHODS

This prospective questionnaire-based study was conducted in the Department of Ophthalmology, at a tertiary care hospital in northern India to assess the nursing staff and final year B.Sc. nursing students about their knowledge of emergency management of ocular trauma. A total of 82 participants were randomly selected from the nursing staff as well as the B.Sc. final year nursing students and were asked to answer a questionnaire, based on their knowledge of the emergency management of ocular trauma. Data recorded was analysed using SPSS version 26.

RESULTS

The maximum score was 30 for answering the questions in the questionnaire. The mean score was found to be 23 among the nursing staff and a mean score of 21 among nursing students. A better overall score was noted among subjects who had experience working in Ophthalmology and Emergency Care.

CONCLUSIONS

It was found that there was a significant relationship between knowledge about emergency management of ocular trauma and variables like gender and work experience in the Department of Ophthalmology and Emergency Care. However, there was no significant association between knowledge of management of ocular trauma and the total number of working years. Knowledge regarding concepts about chemical injury was found to be low in all groups. Training and updating of knowledge on all aspects of ocular trauma must be done with an emphasis on emergency management during their posting in the Department of Ophthalmology and Emergency Care.
Evaluation of Urban Vegetation Phenology Using 250 m MODIS Vegetation Indices
Authors: Zhang Hongxin , Wang Xiaoyue , Peng Dailiang
Published: June 2022

The dynamics of urban vegetation phenology play an important role in influencing human activities. Previous studies have shown high-resolution remote sensing as a tool for urban vegetation mapping, but the low temporal resolution of these data limits their use for phenological modeling.
Therefore, it is of great significance to evaluate Moderate Resolution Imaging Spectroradiometer (MODIS) imagery for urban vegetation phenology monitoring. Here, we extracted the start and end of growing season (SOS and EOS) in urban ecosystems based on both the Normalized Difference Vegetation
Index (NDVI) and the Enhanced Vegetation Index (EVI) from the 250 m MODIS vegetarion indices product (MOD13Q1). Then the accuracies of the satellite-derived SOS and EOS were evaluated through comparing phenological observations at 18 ground sites. Results showed that SOS was most consistent
with the prime of leaf unfolding date and EOS was most consistent with the beginning of leaf coloring date. Overall, EVI was found to have stronger predictive strength than NDVI in detecting urban vegetation phenology in terms of both higher correlation coef- ficients and lower root-mean-square
errors. In addition, the dynamic threshold method was more accurate in deriving SOS, while the double logistic method had relatively higher accuracy in deriving EOS .
Colección de referencia de maderas para el estudio del registro antracológico del litoral Atlántico Patagonia Sur de la República Argentina (Provincias de Santa Cruz y Tierra del Fuego)
Authors: Franch Bach Anna , Ciampagna M. Laura , Mansur M. Estela , Zubimendi Miguel A. , Capparelli Aylen
Published: June 2022

In the archaeological sites of hunter-gatherer societies in Patagonia, carbonized woody plant macro-remains are the most frequent and ubiquitous of the archaeobotanical record. For this reason, it is essential to create a reference collection that allows a correct identification and interpretation of anthracological remains and to infer collection and management practices. The objective of this work is to present the reference collection of woods potentially used by hunter-gatherer societies of the southern coast of Patagonia and the island of Tierra del Fuego. In addition, to create dichotomous keys and to apply the results obtained to the identification of archaeological charcoals from two archaeological sites of the late Holocene of the southern Atlantic coast of Patagonia and Tierra del Fuego (Palo Alto and CSP2017). The importance of this work is due to the few anatomical descriptions for many of the species of the Atlantic coast of Patagonia, especially for taxa that do not have commercial use.
Perbandingan Tingkat Pengetahuan dan Sikap serta Praktik Pencegahan Skabies Pada Santri Pesantren di Banda Aceh dan Aceh Besar
Authors: Rahmatyawati Cut , Asniar Asniar , Atika Syarifa
Published: June 2022

Introduction: Inadequate knowledge, attitude, and personal hygiene behavior contribute to the prevalence of scabies among students living together at the dorm of Islamic Boarding School (IBS). Moreover, the differences in the schools located in urban and rural areas may also increase these vulnerabilities. This study aimed to compare the level of knowledge and attitudes with the practices of scabies prevention among students of Islamic Boarding School in Banda Aceh and Aceh Besar.Methods: This research used a comparative study design with a cross-sectional approach, involving 86 students in Banda Aceh and Aceh Besar selected by stratified random sampling method. Data was collected using a questionnaire measuring knowledge, attitude, and perceived practice of scabies prevention, which was developed from Bloom's theory, and previously tested its psychometric properties. Data were analyzed using Independent Sample T-Test and Mann Whitney-U Test.Results: Based on the results of the study, it was found that the students of Aceh Besar had a greater experience of scabies (27.9%) than the students of Banda Aceh (18.6%). In the practice of personal hygiene, it is known that more than 85% of students have the habit of exchanging towels which is a factor in the occurrence of scabies. The results indicated a significant difference in students' attitudes in preventing scabies (p-value 0.025). However, there were no significant differences in the level of knowledge (p-value 0.067), personal hygiene habits (p-value 0.055), and the frequency of personal hygiene activities of students (p-value 0.490 α=0.05) in preventing scabies.Conclusion: There is a significant difference in attitudes towards scabies prevention among students in Banda Aceh and Aceh Besar. It is necessary to perform alternate interventions for students in both locations to increase positive attitudes in preventing scabies.
Gambaran Tingkat Spiritualitas Anggota Paduan Suara Mahasiswa
Authors: Bestari Dhiva Putri , Ulliya Sarah , Sulisno Madya , Dwidiyanti Meidiana , Nurmalia Devi
Published: June 2022

Introduction: Singing particularly in a choir, has effects on long-life health, better nutrition, and a better perception of quality of life and health and has a role in the recovery and healing process. The spirituality of the choir is closely related to the connections among the members, teammates, coaches, and with God. The purpose of this study was to describe the spiritual level of members of the choir.Methods: This study was a descriptive quantitative type and designed using the “Daily Spiritual Experience Scale” (DSES) questionnaire to determine the level of spirituality which is then analyzed univariately. Thera ware 50 respondents joint in thia research.  The research was conducted online through the “g-form” and analysed using univariate analysis. Results: A total of 50 respondents participated and 9 respondents (18%) had moderate spirituality levels and 41 respondents (82%) had high spirituality levels.Conclusion: The results of this study can be concluded that most of the Choir have high spirituality levels
Hubungan Dukungan Keluarga dan Efikasi Diri dengan Motivasi Lansia Hipertensi Dalam Mengontrol Tekanan Darah
Authors: Br.Siahaan Resty Hoky , Utomo Wasisto , Herlina Herlina
Published: June 2022

Introduction: Family support and self-efficacy are ways to increase the motivation of the elderly to control their blood pressure regularly. This study aims to determine the relationship between family support and self-efficacy with the motivation of elderly hypertension in controlling blood pressure.Methods: The variables in this study were the relationship between family support and the motivation of the elderly with hypertension in controlling blood pressure and the relationship between self-efficacy and the motivation of the elderly in controlling blood pressure. This study used a descriptive correlation design with a cross sectional approach. The research sample was 65 elderly who were taken using the snowball sampling method. The analysis used bivariate analysis using chi-square test.Results: There were 36 respondents (55.4%) who received high family support to control blood pressure. Based on self-efficacy, 34 respondents (52.3%) had high self-efficacy in controlling blood pressure. Based on motivation, there are 40 respondents (61.5%) who have high motivation in controlling blood pressure. The results of statistical tests showed that there was a significant relationship between family support and the motivation of the elderly with hypertension in controlling blood pressure with p value (0.001) < alpha (0.05), while the self-efficacy variable with the motivation of the elderly in controlling blood pressure obtained p value (0.000) < alpha (0.05).Conclusion: Family support and self-efficacy have a significant relationship to the motivation of the elderly in controlling blood pressure.
Hubungan Peran Suami dan Social Culture dalam Pemberian ASI di Pekanbaru, Riau
Authors: Siregar Yossi Yolanda , Lestari Widia , Hasanah Oswati
Published: June 2022

Introduction: The low breastfeeding rate for infants is known to be influenced by the role of the husband and the social culture applied to a family. The purpose of this study was to determine the relationship between the role of husbands and social culture with breastfeeding in the Rejosari Health Center Work Area, Pekanbaru City.Methods: The research design is correlational with the research variables of husband's role, social culture, and breastfeeding. The sample in this study was 75 respondents with the criteria that the mother lived with the baby and husband, the mother was willing to be a respondent, the mother was physically and mentally healthy, and the mother was able to read and write using purposive sampling data collection techniques. The analysis in this study is a bivariate analysis using the Chi-square test.Results: As many as 56% of husbands have a low role in supporting breastfeeding and 44% of husbands have a high role in supporting exclusive breastfeeding. Based on social culture, there are 52.8% of mothers who behave positively but give non-exclusive breastfeeding. The results of statistical tests showed a significant relationship between the husband's role and breastfeeding with the results of p value (0.000) < (0.05), while the social culture variable with exclusive breastfeeding showed no significant relationship where the p value (0.183) > (0.05).Conclusion: The high role of husbands in supporting mothers can affect mothers in giving exclusive breastfeeding, while social culture does not have a significant relationship with exclusive breastfeeding.
Hubungan Perilaku CERDIK terhadap Pengontrolan Tekanan Darah pada Lansia Hipertensi di Masa Pandemi COVID-19
Authors: Seprina Seprina , Herlina Herlina , Bayhakki Bayhakki
Published: June 2022

Introduction: Most cases who suffer from hypertension are the elderly for that behavior is needed to control blood pressure, one of which is CERDIK behavior. CERDIK behavior consists of several lifestyles to improve and control health. So this study aims to find out how the relationship between CERDIK behavior on blood pressure control in the elderly during the COVID-19 pandemic.Methods: This study used a descriptive design with a cross sectional method. The sample in this study was 65 elderly people who were taken using purposive sampling and snowball sampling techniques. Data collection tools in this study were manual tensioner, stethoscope, and CERDIK Behavior questionnaire containing 19 questions that had been tested for validity (0.378-0.693) and reliability test (0.899). Inclusion criteria were respondents who were 60 years old, suffered from hypertension and were able to do physical activity. This research was conducted in Puskesmas Simpang Tiga, Pekanbaru City.Results: The results of this study indicate that majority elderly hypertensive people have cerdik behaviors good as many as 37 people (56.9%) and controlled arterial pressure of 35 people (53.8%). There is a significant relationship between cerdik behavior on blood pressure control with p values (0,005).Conclusion: As a result, it can be concluded that there is a significant relationship between cerdik behavior with control blood pressure in hypertension elderly during the Covid-19 period.
Peran Profesionalitas Perawat yang Bekerja secara Sukarela di RSUD Kefamenanu: Deskriptif Kualitatif
Authors: Usfinit Paskalis Malafu , Margawati Ani , Dwiantoro Luky
Published: June 2022

Introduction: The role of nurses who work voluntarily in hospitals has contributed to hospital services. In this study, it is still limited to obtain research results that discuss the phenomenon of nurses who work voluntarily.Objective: This study was to describe the professional role of nurses who work voluntarily at the Kefamenanu General Hospital.Methods: This research was a qualitative method with a qualitative descriptive approach. The sampling technique was a purpose sampling technique. The instrument in this study used an interview guide. The samples in this study was the stake holder who has the authority in TTU district. This research was conducted at the Kefamenanu Hospital. The data was collected by in-depth interviews with semi-structured interviews and analysed by using content analysis.Results: Nurses who work voluntarily and salaries are paid below the regional minimum wage standard have a very important role in the Kefamenanu Hospital. The role is to have multiple skills, contribute to the improvement of services in hospitals and have a positive impact on services in hospitals.Conclusion: The nurses always have a high commitment when they are working in kefamenanu hospital. They work professionally and do not care attentionally with the salary they will receive.
UNDERSTANDING THE MODERATOR ROLE OF COVID-19 PANDEMIC ANXIETY ON THE RELATIONSHIP BETWEEN INTERNET ADDICTION AND ONLINE SHOPPING ADDICTION
Authors: LEBLEBİCİOĞLU Burak , AYSUNA TÜRKYILMAZ Ceyda
Published: June 2022

Internet addiction is one of the most important drivers of online shopping addiction. During Covid-19

pandemic people had to spend more time in their homes and had to use internet more than before to

do their tasks. One of the tasks that should be performed on internet is shopping. On the other hand,

it’s obvious that Covid-19 pandemic has negative outcomes in terms of economy and psychology. One of

the negative outcomes of pandemic is anxiety. In this study, the moderator role of Covid-19 anxiety on

the relationship between internet addiction and online shopping addiction is examined. Although several

studies are conducted during pandemic about the effects of pandemic this topic is not investigated. In this

regard, this study is unique and suppose to add value to the related literature. The results of the analysis

show that online shopping addiction consisted of three factors. Among those factors, the moderator role

of Covid-19 anxiety was supported only for the negative effect factor. In other words, Covid-19 anxiety has

moderating effect on the relationship between internet addiction and negative effect dimension of online

shopping addiction. Finally, some suggestions were provided for the online shopping firms depending on

the findings of the study.
Early loss of glutathione ‐s‐ transferase (GST) activity during diverse forms of acute renal tubular injury
Authors: Zager Richard A. , Johnson Ali C. M.
Published: June 2022

Glutathione‐S‐transferases (GSTs) are a diverse group of phase II detoxification enzymes which primarily evoke tissue protection via glutathione conjugation to xenobiotics and reactive oxygen species. Given their cytoprotective properties, potential changes in GST expression during AKI has pathophysiologic relevance. Hence, we evaluated total GST activity, and the mRNA responses of nine cytosolic GST isotypes (GST alpha1, kappa1, mu1/5, omega1, pi1 sigma1, theta1, zeta1 mRNAs), in five diverse mouse models of AKI (glycerol, ischemia/reperfusion; maleate, cisplatin, endotoxemia). Excepting endotoxemia, each AKI model significantly reduced GST activity (~35%) during both the AKI “initiation” (0‐4 h) and “maintenance” phases (18 or 72 h). During the AKI maintenance phase, increases in multiple GST mRNAs were observed. However, no improvement in GST activity resulted. Increased urinary GST excretion followed AKI induction. However, this could not explain the reduced renal GST activity given that it also fell in response to ex vivo renal ischemia (i.e., absent urinary excretion). GST alpha, a dominant proximal tubule GST isotype, manifested 5–10‐fold protein increases following AKI, arguing against GST proteolysis as the reason for the GST activity declines. Free fatty acids (FFAs) and lysophospholipids, which markedly accumulate during AKI, are known to bind to, and suppress, GST activity. Supporting this concept, arachidonic acid addition to renal cortical protein extracts caused rapid GST activity reductions. Based on these results, we conclude that diverse forms of AKI significantly reduce GST activity. This occurs despite increased GST transcription/translation and independent of urinary GST excretion. Injury‐induced generation of endogenous GST inhibitors, such as FFAs, appears to be a dominant cause.
Conformal metrics with prescribed scalar and mean curvature
Authors: Cruz-Blázquez Sergio , Malchiodi Andrea , Ruiz David
Published: June 2022

We consider the case with boundary of the classical Kazdan–Warner problem in dimension
greater or equal than three, i.e. the prescription of scalar and boundary mean curvatures via conformal deformations
of the metric. We deal in particular with negative scalar curvature and
boundary mean curvature of arbitrary sign, which to our knowledge has not been treated
in the literature. We employ a variational approach to prove new existence results,
especially in three dimensions. One of the principal issues for this problem is to obtain compactness
properties, due to the fact that bubbling may occur with profiles of
hyperbolic balls or horospheres, and hence one may lose either pointwise estimates on the
conformal factor or the total conformal volume. We can sometimes prevent them using
integral estimates, Pohozaev identities and domain-variations of different types.
On the oppositions that underlie the distinctions displayed by Russian causal clauses
Authors: Pekelis Olga
Published: June 2022

This article studies Russian causal clauses employing formal contrasts that causal clauses manifest crosslinguistically. I explore two approaches that have been proposed to account for such contrasts: the coordination-subordination approach and the approach assuming that causal clauses represent different classes of adverbial clauses that differ in their degree of syntactic integration with the host clause. It is argued that the Russian data cannot be consistently accounted for unless a combination of the two approaches is applied. The analysis also reveals that the degrees of syntactic integration encoded by Russian causal clauses are different from those claimed for German causal clauses by previous research. Thus, while the degree of syntactic integration proves to be a valid parameter to compare systems of causal clauses crosslinguistically, its specific realizations may vary. Furthermore, the juxtaposition of the two approaches poses the question as to what the difference is between syntactically non-integrated adverbial clauses and coordinated clauses. I tentatively suggest that they too differ in terms of the degree of integration, but this difference belongs to the level of information packaging in discourse and not to the level of syntax.
Unicity of meromorphic functions concerning differences and small functions
Authors: He Zhiying , Xiao Jianbin , Fang Mingliang
Published: June 2022

In this paper, we study the unicity of meromorphic functions concerning differences and small functions and mainly prove two results: 1. Let

f

f

be a transcendental entire function of finite order with a Borel exceptional entire small function

a

(

z

)

a\left(z)

, and let

η

\eta

be a constant such that

Δ

η

2

f
≢
0

{\Delta }_{\eta }^{2}\hspace{0.25em}f\not\equiv 0

. If

Δ

η

2

f

{\Delta }_{\eta }^{2}\hspace{0.25em}f

and

Δ

η

f

{\Delta }_{\eta }\hspace{0.25em}f

share

Δ

η

a

{\Delta }_{\eta }a

CM, then

a

(

z

)

a\left(z)

is a constant

a

a

and

f

(

z

)

=
a
+
B

e

A
z

f\left(z)=a+B{e}^{Az}

, where

A
,
B

A,B

are two nonzero constants; 2. Let

f

f

be a transcendental meromorphic function with

ρ

2

(

f

)

<
1

{\rho }_{2}(f)\lt 1

, let

a

1

{a}_{1}

,

a

2

{a}_{2}

be two distinct small functions of

f

f

, let

L

(

z
,
f

)

L\left(z,f)

be a linear difference polynomial, and let

a

1

≢
L

(

z
,

a

2

)

{a}_{1}\not\equiv L\left(z,{a}_{2})

. If

δ

(

a

2

,
f

)

>
0

\delta \left({a}_{2},f)\gt 0

, and

f

f

and

L

(

z
,
f

)

L\left(z,f)

share

a

1

{a}_{1}

and

∞

\infty

CM, then

L

(

z
,
f

)

−

a

1

f
−

a

1

=
c
,

\frac{L\left(z,f)-{a}_{1}}{f-{a}_{1}}=c,

for some constant

c
≠
0

c\ne 0

. The results improve some results following C. X. Chen and R. R. Zhang [Uniqueness theorems related difference operators of entire functions, Chinese Ann. Math. Ser. A 42 (2021), no. 1, 11–22] and R. R. Zhang, C. X. Chen, and Z. B. Huang [Uniqueness on linear difference polynomials of meromorphic functions, AIMS Math. 6 (2021), no. 4, 3874–3888].
Existence results for neutral evolution equations with nonlocal conditions and delay via fractional operator
Authors: Zhang Xuping , Sun Pan
Published: June 2022

In this paper, we study the existence of solutions for the neutral evolution equations with nonlocal conditions and delay in

α

\alpha

-norm, which are more general than in many previous publications. We assume that the linear part generates an analytic semigroup and transforms them into suitable integral equations. By using the Kuratowski measure of noncompactness and fixed-point theory, some existence theorems are established without the assumption of compactness on the associated semigroup. Particularly, our results cover the cases where the nonlinear term

F

F

takes values in different spaces such as

X

α

{X}_{\alpha }

. An example of neutral partial differential system is also given to illustrate the feasibility of our abstract results.
Effects of heat treatment on some magnetic properties of amorphous alloys containing (Fe–Ni)1−x
M
x
(M = Si, B)
Authors: Rafiyev Nurlan
Published: June 2022

Herein, the effect of various treatment modes on the magnetic properties of amorphous alloys Fe49Ni29Si9B13 and Fe59Ni19Si9B13 obtained by melt spinning was considered. Samples from both alloys were heat-treated separately in the magnetic field and without the field. An increase in soft magnetic properties was detected during the transition to the crystalline phase (Hc = 0.63Oe, Bm = 1.55T, Br = 2.16T). It was determined that the soft magnetic properties of materials disappear with the formation of crystalline phases. The obtained materials were applied by replacing the electrical steel in the core of the LC1E2501 contactor produced by Schneider. During the operation, the result was 7% higher than the plant resource.
The distribution, type, popularity, size and availability of river-run gravel and crushed stone for use in land drainage systems and their suitability for mineral soils in Ireland
Authors: Byrne I. , Healy M. G. , Fenton O. , Tuohy P.
Published: June 2022

The performance of land drainage systems installed in mineral soils in Ireland is highly variable, and is dependent on, amongst other factors, the quality and suitability of the aggregate used. In Ireland, aggregate for land drainage systems is usually river-run gravel and crushed stone. This study classified the distribution, type, popularity, size and availability of aggregates for land drainage systems throughout Ireland and quantified their suitability for use in mineral soils. Eighty-six quarries were surveyed. Limestone and river-run gravel (80% of lithologies) are widespread throughout the country. The quarry aggregate sizes (“Q sizes”), reported by the quarries as either a single size, that is, “50 mm”, or a graded size, that is, 20–40 mm, were variable, changed across lithology and region and were, in most cases, larger than what is currently recommended. A particle size distribution analysis of 74 samples from 62 quarries showed that individual Q sizes increased in variability with increasing aggregate size. In some regions, the aggregate sold does not meet current national regulations, which specify an aggregate size ranging from 10 to 40 mm. The suitability of these aggregates for drainage in five soils of different textures was compared using three established design criteria. It was found that the aggregate in use is too large for heavy soil textures and is therefore unsuitable as drainage envelope material. Guidance for contractors, farmers and quarry owners will be required, and investment may be needed by quarries to produce aggregate that satisfies design criteria. An aggregate size, based on one or a combination of established aggregate design criteria, where an analysis of the soil texture is conducted and an appropriate aggregate is chosen based off its 15% passing size, is required.
Features of erythrocyte electrophoretic mobility in programmed hemodialysis patients
Authors: Boldyreva Ekaterina S. , Kudryavtsev Egor V.
Published: June 2022

Objective: to analyze the electrophoretic properties of erythrocytes in patients receiving programmed hemodialysis treatment.
Materials and Methods. The study included 100 patients with an established diagnosis of stage 5D chronic kidney disease, receiving programmed hemodialysis treatment. The control group included 17 healthy blood donors. The following indicators of erythrocyte electrophoretic activity were evaluated: oscillation amplitude, percentage of motile cells, ellipticity, and aggregation index.
Results. Compared with the control group, we revealed significant changes in the amplitude of oscillations and the percentage of motile cells (p<0.001). No significant gender-dependent differences were observed (p>0.05). Statistically significant differences between young and senile age groups (p=0.048) were observed in the average oscillation amplitude, whereas ellipticity differed significantly in middle-aged vs. senile patients (p=0.040) and elderly vs. senile subjects (p=0.035). As for the effect of hemodialysis treatment duration, a reduction in the oscillation amplitude was observed when comparing maximum with minimum duration: less than 1 year (p=0.029) and 1 year (p=0.035). Aggregation index values were the highest in the groups with the minimum (p=0.044) and maximum (p=0.035) dialysis duration.
Conclusion. In hemodialysis patients, the oscillation amplitude of erythrocytes was significantly reduced, with assumed tendency for further decrease associated with duration of hemodialysis treatment.
ANALISIS KEPERLUAN KOMPETENSI PENGURUS DALAM MENGURUS SISTEM GAJI BERDASARKAN PRESTASI
Authors: ABD RAZAK MOHD RIDWAN , Enah binti Ali
Published: June 2022

Abstract - Management of wages system is an important role in organizational management. It has been a topic of discussion and debate among scholars in the context of organizational management as well as academic. This study is intended to identify and understand in a deeper basis on the essential dimensions of the competencies that must be possessed by a manager to manage performance-based wages. In depth reviews were made through an analysis of 88 latest literature studies published between 2013 and 2020 in relation to performance-based wages management. Findings from this study showed that there are three essential dimensions of competencies that need to be possessed by the manager to manage the performance-based wages system efficiently and effectively which is communication, participation, and performance appraisal. In this regard, it is a priority to the organization to choose and/or equip the manager who is responsible for managing performance-based wages system with these three dimensions of competency to realize the goals of employees and organizations.
 
Abstrak - Pengurusan sistem gaji merupakan fungsi penting dalam pengurusan organisasi. Ia telah menjadi topik perbincangan dan perdebatan dalam kalangan sarjana sama ada dalam konteks pengurusan organisasi dan juga akademik. Kajian ini adalah bertujuan untuk mengenal pasti dan memahami dengan lebih mendalam tentang dimensi-dimensi penting dalam kompetensi yang perlu dimiliki oleh seseorang pengurus untuk mengurus sistem gaji berdasarkan prestasi. Penelitian yang mendalam telah dilakukan melalui analisis terhadap 88 kajian-kajian literatur terkini yang diterbitkan antara tahun 2013 hingga 2020 berkaitan dengan pengurusan gaji berdasarkan prestasi. Penemuan daripada kajian ini menunjukkan bahawa terdapat tiga dimensi penting kompetensi yang perlu dimiliki oleh pengurus untuk mengurus sistem gaji berdasarkan prestasi dengan cekap dan berkesan iaitu komunikasi, penglibatan, dan penilaian prestasi. Sehubungan itu, adalah menjadi keutamaan kepada organisasi untuk memilih dan/atau melengkapkan pengurus yang bertanggungjawab mengurus sistem gaji berdasarkan prestasi dengan ketiga-tiga dimensi kompetensi ini bagi merealisasikan matlamat pekerja dan organisasi.
INTEGRASI PEMBELAJARAN SAINS DAN LATIHAN BIOFEEDBACK DALAM MENINGKATKAN PRESTASI MATA PELAJARAN SAINS MURID SEKOLAH RENDAH
Authors: Yaakob Hasmiza , Abdul Wahab Muhammad Nubli
Published: June 2022

Abstract - Individuals have been shown to improve their performance through biofeedback training approaches. To that end, the goal of this research is to see how successful merging science learning and biofeedback training is in improving primary school students' science performance. This quantitative study used a quasi-experimental method, with students receiving biofeedback training while learning science and completing a pre- and post-test. Following the Pre- and Post-test activities, the HRV scores of students with different levels of science achievement revealed that the Post-test HRV scores increased. As per the conclusions of the study, combining HRV biofeedback training with science learning can help students succeed in their studies.
 
Abstrak - Teknik latihan Biofeedback diketahui mampu membantu individu untuk meningkatkan prestasi. Untuk itu, kajian ini bertujuan melihat keberkesanan intergrasi pembelajaran Sains dan latihan Biofeedback bagi melihat keberkesanannya terhadap prestasi mata pelajaran Sains murid sekolah rendah. Kajian kuantitatif ini dilakukan secara kuasi eksperimen melibatkan ujian Pra dan ujian Pasca dimana murid diberikan latihan Biofeedback semasa mereka menjalani pembelajaran sains. Dapatan dari skor HRV murid pelbagai tahap pencapaian selepas ujian Pra dan ujian Pasca menunjukkan terdapat peningkatan dalam skor HRV bagi ujian Pasca. Berdasarkan dapatan kajian, penggabungan teknik latihan HRV Biofeedback dengan integrasi pembelajaran Sains berupaya membantu murid meningkatkan pencapaian mereka. Dapatan kajian merumuskan teknik latihan HRV Biofeedback sesuai digunakan dalam membantu murid sekolah rendah luar bandar meningkatkan pencapaian dalam mata pelajaran Sains dan juga mata pelajaran lain yang memerlukan penjajaran teknik pembelajaran yang lebih berkesan.
PEMIKIRAN INTELEKTUAL SYEIKH ABD AL-SAMAD AL-FALIMBANI
Authors: Mohamed Mohamad Zainuddin , Ahmad Irfan Ikmal Hisham
Published: June 2022

Abstract –  Sheikh Abdul Al-Samad Al-Falimbani is a Sufi scholar from Palembang who is famous for his many writings, seminars, and public debates on the theme of Sufism. This article seeks to reveal some of the backgrounds of Sheikh Abdul al-Samad who is referred to as the "Worldly Known Scholar" in terms of genealogy, name, place of birth, educational background, work, teachers and students. His death was also highlighted. The research method is qualitative in nature from the library research type. It applies the method of documentation from library materials such as doctoral theses, scholars as well as articles, papers, journals, books and classic books related to Sheikh Abd al-Samad al-Falimbani.
 
Abstrak - Syeikh Abdul Al-Samad Al-Falimbani adalah ulama Sufi yang berasal dari Palembang yang terkenal dalam banyak penulisan, seminar, dan perbahasan umum bagi tema Sufisme. Tulisan ini berusaha mengungkap beberapa latar belakang Syeikh Abdul al-Samad yang disebut sebagai “Ulama Yang Dikenali Seluruh Dunia” dalam aspek salasilah, nama, tempat kelahiran, latar belakang pendidikan, hasil karya, guru dan anak murid beliau.  Kematian beliau turut diketengahkan. Kaedah kajian adalah bersifat kualitatif dari jenis kajian perpustakaan. Ia menerapkan kaedah dokumentasi dari bahan-bahan perpustakaan seperti tesis kedoktoran, sarjana dan juga artikel, kertas kerja, jurnal, buku dan kitab-kitab klasik berkait dengan Syeikh Abd al-Samad al-Falimbani.
REPRESENTATION OF MENTAL PROCESSES AND THE USE OF ARTEFACTS IN STRUCTURING SPANISH LANGUAGE SENTENCES
Authors: Shahril Ismail  , Robe'ah Yusuf  , Pooveneswaran Nadarajan  , Jamal Rizal Razali
Published: June 2022

According to Sociocultural Theory (Vygotsky, 1978), the mental function can be enhanced through the process of mediation of language or cultural artefacts. This theory was based on the field of study that focuses on the concept of ‘collaboration’ with experts, peers or those who are more knowledgeable in the Proximal Development Zone (ZPD) to improve students' abilities. Most studies that involve the concept of ZPD are more focused on collaboration/effectiveness of interaction with experts or peers. The effectiveness of these collaborations is also often measured by pre-post test research designs. However, the mental activity within the ZPD that displays the use of artefacts during the writing process to result in the final text resulting from this collaboration is rarely demonstrated. Even in scenarios where students are learning a foreign language in Malaysia (especially Spanish), most of the time they were able to perform written assignments at their convenience and without the help of an expert or teacher. How students solve lexical and syntactic problems while structuring Spanish sentences without the presence of an expert during the sentence structuring process is a matter that is rarely studied. This study focuses on mental processes that display the use of artefacts that occur in ZPD during the Spanish writing process. Using the TAP (Think Aloud Protocol) method, the findings not only was able to display the ways to use the artefacts but also able to show representations of the mental process of lexical and syntactic acquiring activities. This study displays several forms of the use of language artefacts and social artefacts to solve lexical and syntactic problems encountered while structuring Spanish sentences. These findings also provide pedagogical implications in the teaching of foreign languages ​​such as Spanish.
Pemodelan Runtun Waktu Harga Saham Bulanan BBRI.JK dengan Metode MODWT-ARIMA
Authors: 'Aina Maula Qorri , Hendikawati Putriaji , Walid Walid
Published: June 2022

MODWT-ARIMA is a time series modeling that combines the MODWT process and the ARIMA process. The MODWT process is used as pre-processing data while the ARIMA process as a time series modeling for data from MODWT decomposition. This study aims to show that time series modeling with a combined MODWT-ARIMA process provides more accurate forecast result compared to the ARIMA model. The modeled data is  monthly time period data of BBRIâ€™s stock price started from January 2018 to July 2018. Accuracy measurement of the forecasting result is based on the RMSE value. The result is the MODWT-ARIMA model has a RMSE value  which is smaller than the ARIMA model with RMSE  Forecasting value using MODWT-ARIMA method for the period January 2018 to July 2018 are, 3687,560, 3571,892,  3287,686, 3072,610, 2832,533, 3147,472, 2964,491. The result of diagnostic checking from ARIMA model for D2, D3, and S3, shows that the residual model is not white noise while of the ARIMA model for the time series of monthly stock prices show thet the residual model is white noise. Theoritically, a model that has no white noiseâ€™s residual is considered to be less able to describe the properties of the observed data and further residual modeing should be done. However, this research is sufficient for the ARIMA model and it turns out that it has been able to show that the MODWT-ARIMA model is more effective than the ARIMA model.