bluuebunny/crossref_metadata_2025 huggingface dataset:
Nanotechnology can Provide Therapeutic Agent by Targeting Molecular Structures of SARS-CoV-2 (COVID-19): A Mini-Review
Authors: Ditta Sarwar Allah , Yaqub Atif , Tanvir Fouzia
Published: March 2021

COVID-19 outbreak has hit the world worst at the start of 2020, as of December 11,
2020, more than 1.5 million people have died and more than 68.8 million people have been infected
globally. SARS-CoV-2 induces mild to severe progressive respiratory pneumonia, leading to failure
of different body organs and ultimately death. Hitherto, there are no specific and potential therapeutic
agents available against the virus. The spike protein is a type I surface glycoprotein facilitating
entry of the virus into the host cell via hACE2 receptors. The two subunits of the spike protein have a
polybasic link as cleavage site (PRAR) in SARS-CoV-2, with an additional attachment of O-linked
glycans. SARS-CoV and SARS-CoV-2 have 76.5% similarity in amino acid sequences. The pathogenesis
and viral entry of SARS-CoV-2 are different from SARS-CoV, therefore, it is a dire need of
time to develop a target-based treatment. Alternative strategies and multidisciplinary research approaches
are crucial for developing new antiviral and improved therapies against COVID-19.
Nanotechnology has opened new horizons for evaluating the biological properties and efficacy of
different materials having a biological origin, such as Nigella sativa. It contains various active
components such as thymoquinone, thymol, thymohydroquinone, and dithymoquinone with different
biological potentials. Metallic nanomaterials have been reported to exhibit antiviral activities
against various strains. Understanding molecular interactions and modifying the surface properties
of nanomaterials with optimum activity may result in the development of novel antiviral therapies.
Uses and Applications of Docosahexaenoic Acid (DHA) in Pediatric Gastroenterology: Current Evidence and New Perspective
Authors: Jiménez David González , García Carlos Bousoño , Martín Juan Jose Diaz
Published: March 2021

:

In this paper, we will review the dietary allowances of these fatty acids in the paediatric
population, and also the indications in different pathologies within the field of pediatric gastroenterology.
Finally, we will try to explain the reasons that may justify the difficulty in translating
good results in experimental studies to the usual clinical practice. This “good results” may be too
little to be detected or there may be other causes but misinterpreted as effects of DHA.
Edema-mass Ratio Based On Magnetic Resonance Imaging As A Preoperative Diagnostic Factor For Posterior Fossa Metastasis
Authors: Kaya Ismail , Cingoz Ilker Deniz , Gursoy Merve , Atar Murat , Guvenc Gonul , Uzunoglu Inan , Sahin Meryem Cansu , Yuceer Nurullah
Published: March 2021

Background:

Peritumoral edema of primary brain tumors is an important cause of morbidity and mortality. The number of studies currently available on the prognostic role of peritumoral brain edema in the posterior fossa is extremely limited.

Objective:

Based on the known importance of magnetic resonance imaging in diagnosing supratentorial metastases, this study aimed to investigate the effects of peritumoral edema on survival of patients with posterior fossa metastases and the preoperative diagnostic value of MRI.

Methods:

Edema and mass volumes of 49 patients with posterior fossa metastasis, who underwent surgery during 2012–2016, were measured using magnetic resonance imaging. The edema/mass indices were retrospectively calculated and interpreted by evaluating the demographic, clinical, and survival data.

Results:

The study consisted of 32 (65.3%) male and 17 (34.7%) female participants, with the mean age ± standard deviation of 47.25±29.25 (17–81) years. Among the 49 patients with posterior fossa metastases, 34 (69.4%) had carcinoma, while 15 (30.6%) had non-carcinoma metastases. The edema/mass indices of patients with carcinoma and non-carcinoma metastases were found to be 14.55±9.64 and 1.34±1.08, respectively, and the difference was statistically significant (p<0.001). The mean survival of patients with carcinoma and non-carcinoma metastases was found to be 642±11.52 days and 726±9.32 days, respectively; however, this difference was not statistically significant (p=0.787).

Conclusion:

The edema/mass ratio was found to be a significant diagnostic factor for the prediction
of posterior fossa metastases. Further detailed studies are warranted to investigate the effect of
edema/mass ratio on survival rate.
Diagnosis Model of Paraquat Poisoning Based on Machine Learning
Authors: Wang Xianchuan , Wang Hongzhe , Yu Shuaishuai , Wang Xianqin
Published: March 2021

Background :

The objective of this research was to screen metabolites with specificity differences in the lung
tissue of paraquat-poisoned rats by metabolomics technology and chi-square test method, to provide a theoretical
basis for the study of the mechanisms of paraquat poisoning, and to use machine learning technology to construct
a paraquat poisoning diagnosis model. This provided an intelligent decision-making method for the diagnosis
of paraquat poisoning.

Methods:

18 paraquat-poisoned rats (36 mg/kg) and 16 positive control rats were selected. Lung tissue
from each rat from both groups was extracted and analyzed by GC-MS. The chi-square test for
feature evaluation was used to screen the difference in specific metabolites in the lung tissue between
the paraquat-poisoned rats and the control group, and the SVM classification machine learning
algorithm was used to construct an intelligent diagnosis model.

Results:

In the end, a total of 14 significant metabolic differences were identified between the two
groups (P < 0.05). The sensitivity, specificity, and accuracy of the constructed SVM paraquat poisoning
diagnostic model reached 95%, 95% and 96.67%, respectively.

Conclusion:

Based on metabolomics technology, the chi-square test for feature evaluation was
used to successfully screen the changes of specific metabolites produced in the lungs after paraquat-
poisoning, and the diagnosis model based on SVM was constructed to provide an intelligent decision
for the diagnosis of paraquat poisoning.
A Magnetic Sensor Based on Poly(γ-Glutamic Acid)-Functionalized Iron
Oxide Nanoparticles for Cr3+ Detection
Authors: Yu Zhibo , Jia Liang , Zhu Jianzhi , Shen Mingwu , Li Jingchao , Jiu Jinting , Li Maoquan , Shi Xiangyang
Published: March 2021

Background:

The highly sensitive and selective detection of Cr3+ is critical.

Objective:

We report the development of poly(γ-glutamic acid) (γ-PGA)-functionalized iron oxide nanoparticles (γ-PGA-Fe3O4 NPs) as a magnetic nanosensor for magnetic resonance (MR) detection of trivalent chromium (Cr3+) in aqueous solution.

Methods:

The γ-PGA-Fe3O4 NPs with a mean particle size of 7.3 nm, good colloidal stability and ultrahigh r2 relaxivity (326.8 mM−1s−1) were synthesized via a facile mild reduction approach in the presence of γ-PGA, and used for MR detection of Cr3+.

Results:

Upon exposure to Cr3+, the γ-PGA-Fe3O4 NPs aggregated into nanoclusters as verified by dynamic light scattering due to the coordination of Cr3+ with γ-PGA side chain carboxyl groups, resulting in the decrease in their transverse relaxation time. This MR signal change enables detection of Cr3+ in a concentration range of 0.4-1 nM. We also show that the γ-PGA-Fe3O4 NPs have an excellent selectivity toward Cr3+ and a high recovery percentage of 83.8% or above.

Conclusion:

This study thus demonstrates that the developed γ-PGA-Fe3O4 NPs may be used as a nanoprobe for MR sensing of Cr3+ in water environment.
Phytochemical Investigation of the Antisalmonellal Effect of Cyperus sphacelatus Rottb. (Cyperaceae)
Authors: Mfonku Napoleon A. , Kamsu Gabriel T. , Kodjio Norbert , Ren Jie , Mbah James A. , Gatsing Donatien , Zhan Jixun
Published: March 2021

Background:

Typhoid fever is a major health burden in Sub-Saharan Africa. Conventional
anti-typhoid drugs are becoming more and more unavailable to most patients in Africa due to
the increased costs and emerging drug resistance. Therefore, there is a need for the discovery of new
antimicrobial agents to combat typhoid fever.

Objective:

This work aimed to investigate the bioactive components in Cyperus sphacelatus Rottb.
(Cyperaceae) and test the antisalmonellal activity of the isolated compounds.

Methods:

Compound purification was done through column chromatography. Structure elucidation
was accomplished based on the 1D and 2D NMR, IR and mass spectra. The biological assay was
done using five bacterial strains, including Salmonella enterica subsp. enterica sérovars Typhi
ATCC 6539 (STS), S. enterica subsp. enterica sérovars Typhi (ST), S. enteritidis (STE), S. enterica
subsp. enterica sérovars Typhimurim (STM), and a resistant isolate of S. enterica subsp. enterica
sérovars Typhi (ST566).

Results:

Three natural products were isolated from the methylene chloride extract of the rhizomes
of C. sphacelatus, including a new furanoquinone, scabequinon-6(14)-ene (1) and two known compounds,
cyperotundone (2) and vanillin (3). Compound 1 showed moderate antisalmonellal activity,
with a minimal inhibitory concentration (MIC) of 32 μg/mL against STM and STS. The best inhibitory
result was obtained with compound 2 on STM with a MIC of 8 μg/mL. Compound 2 also gave
the best minimum bactericidal concentration (MBC) of 32 μg/mL on the STM strain.

Conclusion:

The discovery of the three antisalmonellal compounds from C. sphacelatus supports
the addition of this plant to typhoid fever preparations.
PEMINJAMAN KEBIJAKAN (POLICY BORROWING) UNTUK PERENCANAAN PENDIDIKAN
Authors: Sholikhah Ebni
Published: March 2021

Peminjaman kebijakan merupakan bagian dari studi komparasi pendidikan. Meminjam kebijakan dari negara lain menjadi hal biasa di era globalisasi untuk merencanakan pendidikan di suatu negara. Hanya saja, tidak semua ekspektasi atas keberhasilan kebijakan yang diadopsi dari negara lain mampu di capai negara peminjam. Kebijakan baru yang disusun mungkin malah mengandung dan mengundang masalah baru. Artikel ini menggambarkan tentang peminjaman kebijakan dalam perencanaan pendidikan. Beberapa hal yang tercakup antara lain sejarah peminjaman kebijakan, peminjaman kebijakan dalam konteks perencanaan pendidikan, dan faktor-faktor yang mempengaruhi keberhasilan peminjaman kebijakan. Kata Kunci: Peminjaman Kebijakan (Policy Borrowing), Pendidikan Komparatif, Perencanaan Pendidikan
Dimensi proses citizenship pendidikan: Studi kasus di Sanggar Alam (SALAM), Nitiprayan, Yogyakarta
Authors: Raharjo Amrih Setyo , Ferianto Fiki
Published: March 2021

Penelitian ini mengeksplorasi dimensi-dimensi kunci dalam membangun citizenship pendidikan. Hal ini penting untuk melengkapi theoritical framework citizenship pendidikan yang belum tersusun secara spesifik. Penelitian menggunakan metode kualitatif dengan pendekatan studi kasus. Pengumpulan data menggunakan snowballing sampling melalui wawancara, observasi, dan studi dokumen guna menangkap natural setting di Sanggar alam (Salam), Nitiprayan, Yogyakarta. Salam dipilih sebagai objek penelitian karena mengaplikasikan konsep pendidikan yang berbeda dengan versi pemerintah. Metode interpretasi dari Creswell (2007) digunakan untuk menganalisis data. Sementara, metode dari Yin (2003) diaplikasikan untuk menguji kebasahan data. Hasil penelitian menunjukan bahwa ada tiga dimensi untuk membangun citizenship pendidikan, yaitu: 1) Active citizens sebagai prasyarat. Partisipasi akan terwujud saat warga negara melakukan shifting dari beneficiaries menuju active citizens. 2) Kontekstualitas sebagai karakteristik citizenship pendidikan. Belajar akan berkesan saat melibatkan lingkungan dalam prosesnya. Hal ini sejalan dengan konsep Tri Sentra versi Ki Hadjar Dewantara dan pembelajaran eksperimental versi Paulo Freire. 3) Co-production sebagai cara mengeksekusi citizenship pendidikan. Ini merupakan pendekatan untuk menciptakan layanan publik dengan mengakomodasi berbagai pihak. Co-production percaya bahwa kerjasama berbagai pihak akan mempermudah penciptaan layanan publik yang representative. Tiga hal ini adalah rangkaian dimensi untuk membangun citizenship pendidikan.Keyword: citizenship pendidikan, partisipasi, active citizens, kontekstualitas, co-production
Duboka mozgovna stimulacija – prijeoperacijska priprema i procjena pacijenata s Parkinsonovom bolešću
Authors: Kampić Kristina , Vuletić Vladimira , Chudy Darko
Published: March 2021

Parkinsonova bolest druga je najučestalija neurodegenerativna bolest. Najčešći simptomi pacijenata koji boluju od Parkinsonove bolesti su tremor u mirovanju, rigidnost, bradikinezija i poremećaj hoda. Liječenje Parkinsonove bolesti složeno je. Razlog tome je kompleksnost bolesti te dugogodišnja progresija. Liječenje može biti medikamentozno ili invazivnim metodama liječenja poput duboke mozgovne stimulacije. Kod medikamentoznog liječenja koristimo tri kategorije lijekova. Prva kategorija lijekova povećava razinu dopamina u mozgu, druga kategorija lijekova, kao što su antikolinergički lijekovi, smanjuje simptome Parkinsonove bolesti i treća kategorija djeluje na nemotoričke simptome Parkinsonove bolesti. Ako medikamentozno liječenje nije dostatno, danas se najviše primjenjuje duboka mozgovna stimulacija. Duboka mozgovna stimulacija je neurokirurška intervencija kojom se ugrađuje elektroda u područje subtalamičke jezgre, ventralne intermedijalne jezgre ili u područje globus pallidus, jer se motoričke komplikacije Parkinsonove bolesti ne mogu adekvatno kupirati lijekovima. Prije same neurokirurške intervencije važna je prijeoperacijska priprema i procjena pacijenata koji su potencijalni kandidati za ovakav zahvat. U prijeoperacijskoj pripremi i procjeni pacijenata treba sudjelovati multidisciplinarni tim stručnjaka koji uključuje psihologe, psihijatre, neurokirurge, a posebnu ulogu imaju kliničari, neurolozi, koji svoje pacijente najbolje poznaju te mogu procijeniti daljnju kvalitetu života pacijenta nakon ugradnje DBS-a.
Sindrom pekućih usta - što je novo u terapijskom pristupu?
Authors: Mrak Bernarda , Glažar Irena , Zuber Vanessa , Pezelj-Ribarić Sonja , Muhvić Urek Miranda
Published: March 2021

Sindrom pekućih usta predstavlja kompleksan poremećaj kroničnog bola multifaktorijalnoga podrijetla. Sindrom predstavlja izazov u dijagnostici tijekom kliničkog rada. Najveća zastupljenost uočena je u ženskoj populaciji. Prosječna pojavnost kod žena u odnosu na muškarce iznosi 7 : 1. Razvoj sindroma povezuje se s lokalnim, sustavnim, psihološkim i neurološkim poremećajima. Uz pečenje oralne sluznice koje obuhvaća najčešće prednje dvije trećine jezika, pacijenti se javljaju i sa simptomima promjene okusa i suhoće usta. Današnji terapijski pristup obuhvaća medikamentoznu terapiju, kao i bihevioralne i alternativne metode. Svrha ovog rada je prikazati sindrom pekućih usta s osvrtom na terapijski pristup predstavljen u recentnoj literaturi.
Point-of-Care Quantification of Serum Alpha-Fetoprotein for Screening Birth Defects in Resource-Limited Settings: Proof-of-Concept Study
Authors: Srinivasan Balaji , Finkelstein Julia L , Erickson David , Mehta Saurabh
Published: March 2021

Background

Maternal serum alpha-fetoprotein (MSAFP) concentration typically increases during pregnancy and is routinely measured during the second trimester as a part of screening for fetal neural tube defects and Down syndrome. However, most pregnancy screening tests are not available in the settings they are needed the most. A mobile device–enabled technology based on MSAFP for screening birth defects could enable the rapid screening and triage of high-risk pregnancies, especially where maternal serum screening and fetal ultrasound scan facilities are not easily accessible. Shifting the approach from clinic- and laboratory-dependent care to a mobile platform based on our point-of-care approach will enable translation to resource-limited settings and the global health care market.

Objective

The objective of this study is to develop and perform proof-of-concept testing of a lateral flow immunoassay on a mobile platform for rapid, point-of-care quantification of serum alpha-fetoprotein (AFP) levels, from a drop of human serum, within a few minutes.

Methods

The development of the immunoassay involved the selection of commercially available antibodies and optimization of their concentrations by an iterative method to achieve the required detection limits. We compared the performance of our method with that of commercially obtained human serum samples, with known AFP concentrations quantified by the Abbott ARCHITECT chemiluminescent magnetic microparticle immunoassay (CMIA).

Results

We tested commercially obtained serum samples (N=20) with concentrations ranging from 2.2 to 446 ng/mL to compare the results of our point-of-care assay with results from the Abbott ARCHITECT CMIA. A correlation of 0.98 (P<.001) was observed on preliminary testing and comparison with the CMIA. The detection range of our point-of-care assay covers the range of maternal serum AFP levels observed during pregnancy.

Conclusions

The preliminary test results from the AFP test on the mobile platform performed in this study represent a proof of concept that will pave the way for our future work focused on developing a mobile device–enabled quad-screen point-of-care testing with the potential to enable the screening of high-risk pregnancies in various settings. The AFP test on the mobile platform can be applied to enable screening for high-risk pregnancies, within a few minutes, at the point of care even in remote areas where maternal serum tests and fetal ultrasound scans are not easily accessible; assessment of whether clinical follow-up and diagnostic testing may be needed after a positive initial screening evaluation; and development of surveillance tools for birth defects.
The Hittite Notion of Border. A practical view
Authors: Kryszeń Adam
Published: March 2021

The Hittite cuneiform texts (16th-12th cent. BCE) contain a number of detailed descriptions of borders of various countries and territories. Such fragments, mainly found in the international treaties as well as the annals of the kings, clearly reflect the particular formal interest on the part of the Hittite rulers in specific delimitation of political territories.

Although the Hittite listings of the topographical points, which make up a frontier can extend over many lines of texts, one never finds any use of cardinal directions which would indicate the position of these points. Instead, the Hittite scribes applied a peculiar internal reference system that combines the position of the speaker and another point of reference in order to locate a specific part of the border.

The talk will briefly review the corpus of the Hittite border descriptions and discuss how such fragments were conceptualized. It will also tackle the question, whether they reflect a ‘bird’s eye’, cartographic view of the land, or rather a ground-level, hodological perspective.
Utilização de bombas de rotação variável como instrumento de melhoria de eficiência energética
Authors:   Universidade Estadual Vale do Acaraú, Sobral, Brasil, Costa José Nilton de Abreu , Holanda de Castro Marco Aurélio , Costa Luís Henrique Magalhães , Barbosa João Marcelo Costa
Published: March 2021

A operação de sistemas de abastecimento de água necessita frequentemente do funcionamento de bombas hidráulicas, que permitem a condução da água até o consumidor final. Bombear fluidos com máximo rendimento é um requisito fundamental em diversas áreas que utilizam bombas hidráulicas, pois diminuem os gastos com energia elétrica. Diante disso, motivou-se a realização deste trabalho, que objetiva fornecer condições de operacionalidade a sistemas de abastecimento de forma racional, com ênfase na otimização do custo energético, pela criação de um modelo computacional que atua de maneira acoplada ao simulador hidráulico EPANET. A ferramenta desenvolvida fundamenta-se na técnica meta-heurística Particle Swarm Optimization (PSO), tendo como variável de decisão a velocidade de rotação das bombas. Este método tem como objetivo a busca de estratégias operacionais com custo energético reduzido, recorrendo à avaliação do desempenho hidráulico de tais estratégias através do EPANET. Os resultados obtidos evidenciam a eficácia do PSO, tanto pelo encontro de melhores estratégias operacionais como pela redução do tempo computacional necessário para tal realização. Finalmente, realça-se que o desenvolvimento dessa metodologia contribui para o uso de modelos de otimização na operação de sistemas de abastecimento de água em tempo real. The operation of water supply systems often requires the operation of hydraulic pumps, which allow the conveyance of water to the final consumer. Pumping fluids at the best efficiency is a fundamental requirement in many areas using hydraulic pumps, as they reduce energy costs. Therefore, the objective of this work is to provide operational conditions to supply systems in a rational way, with emphasis on the optimization of energy cost, by the creation of a computational model that works in a way coupled with the EPANET hydraulic simulator. The tool developed is based on the meta-heuristic technique Particle Swarm Optimization (PSO), having as a decision variable the rotational speed of the pumps. This method carries out the search for operational strategies with reduced energy cost, while the evaluation of the hydraulic performance of such strategies is carried out in EPANET. Obtained results show the effectiveness of the PSO, both by the encounter of better operational strategies and by the reduction of the necessary computational time. Finally, the development of this methodology contributes to the use of optimization models in the operation of water supply systems in real time.
COMPARATIVE ANALYSIS OF CHINA AND RUSSIA'S LOGISTICS PERFORMANCE UNDER THE BACKGROUND OF «ONE BELT ONE ROAD»
Authors:   XIAOXUE ZHANG Heihe University, ZHANG XIAOXUE
Published: March 2021

With the advancement of the One Belt One Road policy, Sino-Russian trade continues to improve. The level of logistics performance of the two countries directly affects the degree of trade convenience. By analyzing the logistics performance index, we can compare effective suggestions to improve the convenience of cross-border logistics.
Deteksi Motif Batik Menggunakan Ekstraksi Tekstur dan Jaringan Syaraf Tiruan
Authors: Amanullah Raynaldi Fatih , Pujianto Ade , Pratama Bayu Trisna , Kusrini Kusrini
Published: March 2021

Penelitian ini mengajukan sebuah metode klasifikasi batik menggunakan ekstraksi fitur tekstur serta klasifikasi menggunakan jaringan syaraf tiruan (artificial neural network). Metode ekstraksi fitur tekstur yang digunakan adalah DWT, GLCM dan Local Binary Pattern (LBP). Ekstraksi fitur dengan GLCM dan DWT menghasilkan 24 fitur yang terdiri dari 5 fitur GLCM dan koefisien energi dalam 4 sub-band channel hasil dekomposisi. Sementara ekstraksi fitur dengan LBP dilakukan dengan membangun histogram dari matriks hasil LBP. Fitur-fitur tersebut kemudian menjadi masukan bagi jaringan syaraf tiruan untuk kemudian diklasifikasi dalam 5 jenis batik: buketan, ceplok, kawung, parang dan truntum. Dataset yang digunakan adalah 50 gambar batik (10 untuk setiap motif) yang diambil secara acak di internet. Pengujian dilakukan dengan membandingkan dua kelompok fitur: DWT-GLCM dan DWT-GLCM-LBP untuk mengetahui metode ekstraksi fitur yang lebih baik dalam deteksi motif batik. Metode pengujian yang digunakan adalah K-Fold Cross Validation dengan hasil berupa confusion matriks untuk kemudian dihitung nilai akurasi dan F-Measure-nya. Hasil pengujian menunjukkan bahwa penggunaan ekstraksi fitur tekstur DWT-GLCM-LBP mampu mencapai akurasi 74% dengan jenis dekomposisi Daubechies 4 level 3.
Inspection of the Composite Materials
Authors: Jasim Yaser A. , Thabet Senan , Thabit Thabit H.
Published: March 2021

A non-destructive test method is the main method to examine most of the materials, composite materials in particular. There are too many Non-Destructive Test (NDT) methods to inspect the materials such as, Visual Inspection, Liquid Penetrate Inspection, Eddy-Current Inspection, Phased Array Inspection, Magnetic Particle Inspection and Ultrasonic Inspection.

This paper aims to creat a unified methodology for engineers depending on reaserch onion to study the inspection of the composite materials.

The researchers concluded that NDT method is the most suitable method for testing any materials and the composite materials. They also recommended to choose the most suitable NDT method as every materials and composite materials have its own properties as well as the inspection methods had its own capabilities and limitations.
Jpeg/Exif Message Digest Compilation With SHA512 Hash Function
Authors: Fitriyanto Rachmad
Published: March 2021

Security information method for jpeg / exif documents generally aims to prevent security attack by protecting documents with password and watermark. Both methods cannot used to determine the condition of data integrity at the detection stage of the information security cycle. Message Digest is the essence of a file that used to represent data integrity. This study aims to compile a message digest to detect changes that occur in jpeg / exif documents in information security. The research phase consists of five stages. The first stage, identification of the jpeg / exif document structure conducted using Boyer-Moore string matching algorithm to find jpeg/exif segments location. The Second stage is segment content acquisition, conducted based on segment location and length obtained. The Third step, computing message digest for each segment using SHA512 hash function. Fourth stage, jpeg / exif document modification experiments to identified affected segments. The Fifth stage is selecting and combining the hash value of the segment into message digest. Obtained result show message digest for jpeg / exif documents composed of two parts, the hash value of the SOI segment and the APP1 segment. The SOI segment value used to detect modifications for jpeg to png conversion and image editing. The APP1 hash value used to detect metadata editing. The SOF0 hash values use to detect modification for image recoloring, cropping and resizing.
Perancangan Perizinan Santri Menggunakan Bahasa Pemograman PHP/MySQL Di SMP Nurul Ikhlas
Authors: Fadila Riri Ratna , Aprison Wedra , Musril Hari Antoni
Published: March 2021

Perizinan siswa adalah proses siswa mendapatkan izin dari petugas piket untuk tidak mengikuti pembelajaran dikarenakan suatu hal yang mendesak. Perizinan ini membutuhkan suatu pencatatan yang digunakan sebagai arsip. Perizinan ini membutuhkan suatu pencatatan yang digunakan sebagai arsip. Petugas piket sering mendapatkan kendala ketika memberikan izin siswa, yaitu dalam rekap data, dan data izin yang valid. Penelitian ini dilatar belakangi dengan pengurusan perizinan yang masih manual atau belum terkomputerisasi yaitu dengan cara mengisi blangko yang telah disediakan pada masing-masing pihak yang berwenang memberikan izin sesuai dengan alur perizinan  yang telah ditetapkan dan permasalahan yang timbul adalah banyaknya berkas yang hilang dan data perizinan santri tidak valid. Dan untuk mengatasi itu maka di rancanglah seuah program khusus untuk perizinan santri yang ingin meninggalkan lokasi asrama. Program ini dibuat dengan menggunakan PHP murni. Program ini dibuat dengan menggunakan PHP murni. Metode yang digunakan dalam penelitian ini adalah metode penelitian Reseacrh and Development (R&D. Produk yang dihasilkan dalam penelitian ini bisa digunakan oleh staf asrama (wali kamar), staf sekolah (kesiswaan), staf disiplin kegiatan (disgiat/pusat pemberian izin) , serta staf kesehatan (poliklinik). Disgiat (admin) dan wali kamar, wakil kesiswaan. Poliklinik (user. Produk yang dihasilkan dalam penelitian ini bisa digunakan oleh staf asrama (wali kamar), staf sekolah (kesiswaan), staf disiplin kegiatan (disgiat/pusat pemberian izin) , serta staf kesehatan (poliklinik). Disgiat (admin) dan wali kamar, wakil kesiswaan. Poliklinik (user). Sedangkan uji  validitas dari 3 orang expert diperoleh nilai 0,83  yang dinyatakan valid, sedangkan untuk uji praktikalitas dari 3 orang praktisi diperoleh nilai 87 yang dinyatakan Sangat praktis. dan untuk uji efektifitas dari 15 wali kamar diperoleh nilai  0,90 yang dinyatakan sangat efektif.
USABILITY TESTING PADA EVALUASI WEB EGRADUATION UNIVERSITAS AMIKOM YOGYAKARTA
Authors: Anggita Sharazita Dyah
Published: March 2021

Kemajuan teknologi tak pernah lepas dengan teknologi informasi. Pada sebuah perguruan tinggi , teknologi informasi memiliki peran yang cukup besar dalam proses bisnisnya. Perencenaan dan implementasi sistem yang baik pada sebuah teknologi informasi sangat dibutuhkan untuk dapat menyeimbangkan investasi yang telah dikeluarkan. Universitas AMIKOM Yogyakarta merupakan salah satu perguruan tinggi swasta berbasis Information and Communication Technologies (ICT). Dalam mencapai tujuan visi dan misi Universitas, AMIKOM selalu berusaha untuk memenuhi kebutuhan stakeholder salah satunya dengan selalu mengupdate teknologi untuk meningkatkan kinerja. Bagian dari Universitas AMIKOM Yogyakarta yaitu Direktorat Bussiness Placement Center (BPC) dan Alumni sebagai pusat karir yang menjembatani kebutuhan informasi dunia kerja yang diperlukan oleh alumni salah satunya dengan media website Egraduation. Menurut Nielsen dan Loranger (2016) agar sebuah situs mampu bertahan hidup dan tidak ditinggal oleh penggunanya, perlu memperhatikan aspek Usability . Saat ini belum pernah dilakukan evaluasi pada website Egraduation, untuk itu perlu dilakukan evaluasi Usability pada situs Egraduation untuk dapat mengukur tingkat ketergunaan dan permasalahan yang dihadapi pengguna situs sebagai bahan evaluasi. Penelitian akan dilakukan dengan 5 faktor Usability Nielsen. Selain itu hasil penelitian ini juga akan mengukur pengaruh faktor usabilitas terhadap variabel yang terdapat pada penelitian.
ANALISIS GAP TEKNOLOGI INFORMASI MENGGUNAKAN ENTERPRISE ARCHITECTURE BERBASIS TOGAF PADA POLITEKNIK NEGERI PONTIANAK
Authors: Widayanti Tri
Published: March 2021

Pengolahan data mahasiswa antara bagian BAAK dengan tiap-tiap Prodi di Politeknik Negeri Pontianak (POLNEP) selama ini belum memaksimalkan teknologi informasi yang dimiliki. Oleh karena itu, agar proses  pengolahan data mahasiswa lebih baik lagi maka diperlukan Enterprise Architecture untuk pengelolaan teknologi informasi yang baik. Tujuan dari penelitian ini adalah untuk merancang rencana teknologi informasi dengan Enterprise Arcitechture menggunakan The Open Group Architecture Framework (TOGAF) di BAAK Politeknik Negeri Pontianak (POLNEP), untuk meningkatkan pengolahan data dan menyelaraskan antara bisnis dan fungsi teknologi. Metode pengumpulan data yang digunakan dalam penelitian ini adalah studi literature, survei dan wawancara. Model  TOGAF digunakan untuk menganalisis gap atau kesenjangan antara arsitektur target dan arsitektur saat ini. Untuk menyelaraskan fungsi bisnis dan teknologi informasi, Politeknik Negeri Pontianak memerlukan proses bisnis, sistem informasi dan arsitektur teknologi. Hasil penelitian berupa perencanaan teknologi informasi dengan Enterprise Architecture menggunakan TOGAF untuk meningkatkan proses pengolahan data yang terintegrasi antara BAAK dengan tiap-tiap Prodi sehingga lebih efektif dan efisien.
IMPLEMENTASI FRAMEWORK CODEIGNITER DALAM PENGEMBANGAN MARKETPLACE FOTOGRAPHER DI BALI
Authors: Permana Putu Adi Guna , Putra I Gd Windu Sara Adi , Triandini Evi
Published: March 2021

Bali adalah pulau dengan beraneka ragam seni dan budaya agama. Hal ini yang mengundang banyak wisatawan lokal maupun manca negara ingin berkunjung dan berlibur ke Bali. Pengunjung Bali banyak yang mengabadikan kegiatan – kegiatannya, sehingga para fotografer banyak mendapatkan pesanan. Saat ini banyak fotographer yang masih menggunakan media promosi offline atau menggunakan online di berbagai media sehingga masyarakat yang ingin menggunakan jasanya bingung mencari informasi yang benar. Berdasarkan permasalahan tersebut, maka dalam penelitian ini akan mengembangkan marketplace fotographer di Bali dengan menggunakan framework codeigniter. Penggunaan framework ini bermanfaat untuk mempermudah dan meningkatkan efisiensi dalam implementasi rancangan sistem. Hasil pengujian sistem menunjukkan bahwa semua fungsi yang tersedia dalam sistem telah berjalan sesuai dengan rancangannya.
Sentimen Analisis Terkait “Lockdown” pada Sosial Media Twitter
Authors: Alizah Muhammad Dwison , Nugroho Arifin , Radiyah Ummu , Gata Windu
Published: March 2021

Covid-19 telah ditetapkan sebagia Pandemi oleh World Health Organization (WHO). Salah satu antisipasi yang bisa dilakukan adalah dengan melakukan lockdown. Pada penelitian ini, akan disampaikan mengenai pembuatan pemodelan prediksi terkait analisa sentimen terkait “Lockdown” pada media sosial Twitter. Metode yang digunakan adalah dengan melakukan labeling menggunakan Vader dan selanjutnya tweet dilakukan ekstraksi menggunakan TF-IDF, dan dibuatkan pemodelan untuk prediksi sentimen menggunakan Naïve Bayes dan Support Vector Machine. Hasilnya yang didapat dari kedua algoritma tersebut ialah lebih dari 80%. 
Pengembangan Sistem Penilaian Berbasis Penalti Untuk Guru Di SMP Tahfizhul Qur’an Syech Ahmad Chatib
Authors: Islami Hafizah , Derta Sarwo
Published: March 2021

Komputer kini sudah menjadi bagian terpenting dalam setiap pekerjaan manusia. Terutama dalam proses pengumpulan data dan pengolahan informasi yang nantinya akan memberikan informasi konkrit, efektif dan efisien untuk penggunanya. Salah satu bagiannya berkaitan dengan sistem penilaian terhadap guru dalam satuan pendidikan. Penilaian terhadap guru yang wajib dilaksankan pada tiap semesternya, tentu membutuhkan sistem penilaian yang efektif dan efisien, agar dapat terwujud hasil penilaian yang efektif. Maka melalui sistem yang efektif ini dapat dilihat kelebihan dan kekurangan kinerja guru tersebut dalam mengajar dan juga dapat memberikan kemudahan dalam pelaksanaan evaluasinya. Penelitian ini bertujuan untuk mengembangkan dan menghasilkan aplikasi penilaian guru yang tervalidasi dan mendeskripsikan kevalidan, kepraktisan serta keefektifannya. Metode yang digunakan adalah Research and Development versi ADDIE dengan model pengembangan sistem Waterfall. Uji produk yang digunakan yaitu Uji Validitas, Uji Praktikalitas dan Uji Efektifitas dengan hasil : uji validitas oleh validator diperoleh nilai 0,82 dengan kriteria sangat valid, uji praktikalitas oleh praktikalitor diperoleh nilai 94 dengan kriteria sangat praktis dan uji efektivitas oleh efektivator diperoleh nilai 0,95 dengan kriteria sangat tinggi.
Analisis Quality Of Service (QoS) Pada Laboratorium Komputer MAN 3 Karawang
Authors: Lesmana Rudi Wildantoro , Hannie Hannie , Sulistiyowati Nina
Published: March 2021

MAN 3 Karawang saat ini telah menggunakan jaringan internet dan telah menerapkan sistem UNBK. Menurut Kepala Laboratorium Komputer (LabKomp), Bapak Suryadi menyebut bahwa sistem UNBK mulai diterapkan di MAN 3 Karawang yaitu pada tahun 2017 untuk tingkat SLTP dan SLTA. Namun pada tahun 2019 bertepatan dengan pelaksanaan try out Ujian Nasional (UN) tingkat SLTP, di sekolah tersebut pernah mengalami gangguan jaringan internet yang berdampak pada pemberhentiannya kegiatan tersebut untuk tahun 2019. Try out tersebut hanya terlaksana 1 hari dari waktu yang seharusnya yaitu 3 hari, yang berarti hanya terlaksana untuk satu mata pelajaran. Setelah dilakukan wawacara kepada 10 pengguna internet pada MAN 3 Karawang diketahui bahwa pada jaringan internet MAN 3 Karawang sering terjadi gangguan konektivitas dan jaringan internet lambat. Untuk mengatasi hal tersebut dilakukan penelitian yaitu menganalisis kinerja lalu lintas jaringan internet pada MAN 3 Karawang menggunakan teknik QoS (Quality Of Service) dengan parameter yang dijadikan acuan untuk QoS yaitu bandwith, delay, jitter,  throughput, dan packet loss. Metode penelitian yang digunakan pada penelitian ini yaitu metode Action Research. Berdasarkan hasil pada penelitian ini diketahui bahwa kualitas jaringan internet pada MAN 3 Karawang kurang layak untuk melaksanakan UNBK.
Identification et classification des terres cultivables et des sites potentiels pour l’aménagement de retenues collinaires dans l’est du bassin méditerranéen: le cas du Haut-Jbeil (Liban)
Authors:   doctorant en Géographie-Aménagement,Université Jean Moulin Lyon 3, France, Caiserman Arnaud , Faour Ghaleb ,   Directeur du Centre National de Télédétection de Beyrouth (CNRS-L), Mansourieh, Liban, Dumas Dominique ,   Directeur du Centre de Recherche en Géographie-Aménagement à l’Université Jean Moulin Lyon 3, France, Bennafla Karine ,   Directrice du Centre d'études et de documentation économique, juridique et sociale, Le Caire, Egypte, Chemaly Georges ,   Ingénieur agronome, Plan Vert, Jounieh, Liban, Kouroz Salim ,   Ingénieur cartographe, Plan Vert, Jounieh, Liban
Published: March 2021

In the Mount-Lebanon, the agricultural territory of Aaqoura is significant despite high elevations reaching 2100 m. In the 1960’s, apple orchards were subsidized by a state-owned service of planning: the Green Plan, but the increasing urbanization in Lebanon requires nowadays a solid knowledge of the remaining and not yet developed lands for agricultural extension. The challenge of this study is dual: environmental and socio-economic. Two models of potential site identification and location of new cultivable lands and new hill lakes have been developed in this study. These models are based on pedologic, topographic, geologic criteria and simultaneously integrate socio-economic surveys with farmers in order to assess the convenience of such new infrastructures and to strengthen its relevance in this region. The results of these models lead to two maps that locate sites with high potential for the implementation of new infrastructure, but its analysis must be completed through survey’s results. After field verifications of these maps, 14% of the area is still available for new agricultural lands and only 4% for hill lakes on account of steep slopes, permeability of soil, and farmers stressed out economic challenges, such as the lack of profitable markets, which undermines the local agricultural growth. However, farmers are interested in new hill lakes for the purpose of satisfying orchard high water needs. This integrated approach of rural development, appeared as an interesting tool for planning office such as the Green Plan as much as for farmers since they are the first users of these infrastructures.
in two plots of apple of golden Dorset varietyin the region of Draa Ben Khedda and golden Delicious in the Sidi Naamane region (Algeria)
Authors:   Laboratoire de production, sauvegarde des espèces menacées et des récoltes. Influence des variations climatiques. Département de biologie. Faculté des sciences biologiques et des sciences agronomiques. Université Mouloud Mammeri de Tizi-Ouzou 15000. Algérie, Guermah Dyhia , Medjdoub-Bensaad Ferroudja ,   Laboratoire de production, sauvegarde des espèces menacées et des récoltes. Influence des variations climatiques. Département de biologie. Faculté des sciences biologiques et des sciences agronomiques. Université Mouloud Mammeri de Tizi-Ouzou 15000. Algérie
Published: March 2021

Codling moth Cydia pomonella L. is a bio-aggressor that causes considerable damage in apple orchards. In Algeria, in the region of Ain-Touta, the damage caused by this pest reached 82.7% in 1998. Chemical control is most often used to repress this micro-Lepidoptere.The knowledge of the life cycle of the species and its spatio-temporal relationship with its host plant is essential in order to consider an appropriate fight against this pest. Our study focused on the bio-ecology of codling mothin two apple orchards, planted with the varieties of Dorset golden and Golden delicious, in regions of Draa Ben Khedda and Sidi Naâmanein Tizi-Ouzou wilaya (Algeria).The eggs enumeration of this micro-Lepidoptera confirms the existence of two generations in Draa Ben Khedda and three generations in Sidi Naamane.The rate of infestation caused by larvae on the fruits on trees reached a percentage of 4.6% in the Dorset golden plot, and 5.3% on the fruits fallen on the ground. In the Golden Delicious plot, the attacks on fruits present on the trees reached a percentage equal to 17.2%, whereas these attacks reached a level of 20.0% on the fruits fallen on the ground.
Effects of monolayers made from different emulsions on surface water evaporation in a typical Algerian oasis
Authors:   University KASDI MERBAH Ouargla, Laboratory ofWater and Environment Engineering in Saharan Milieu (GEEMS), Saggaï Sofiane , Boutoutaou Djamel ,   University KASDI MERBAH Ouargla, Laboratory of Exploitation and Valorization of Natural Resources in Arid Zones(EVRNZA), El kheir Bachi Oum ,   University of Kasdi Merbah Ouargla. Laboratory of Saharan Bio-resources:   Preservation and Valorization(BRS)
Published: March 2021

The extremely high rate of evaporation from surface water bodies in arid and semi-arid regions greatly reduces optimal utilization of water reservoirs. Therefore, techniques to reduce evaporation are greatly needed. During the last decades, a large number of dams (68 dams)were constructed and distributed over the entire country. Hence, preserving and protecting the stored waterby reducing evaporation is strategic future task of the Algerian state. Experiment was conducted in Touggourt during summer with four Colorado evaporation pans and weather station. Two fatty alcohols emulsion were selected and applied to reduce the evaporation in different pans. The first pan (OP) was filled with water without adding emulsion,while in the second pan (P2, Hexa)Hexadecanol emulsion was added at the concentration of 0.15g/m2. For the third pan (P3, Hexa/Octa)amixture of Hexadecanol/Octadecanol emulsion was added at the same concentration (0.075g Hexa:0.075g Octa)and for the fourth pan (P4, Octa) Octadecanol emulsion was added with a concentration of 0.15g/m2. The different formulations and concentrations were repeated on the respective water surface every three daysin order to form a monolayer.
Healthcare Marketing: An Empirical Study among Lebanese Hospitals
Authors:   School of Business, Lebanese International University, Aoun Malak , Alaaraj Hassan ,   School of Business, Lebanese International University
Published: March 2021

Although most of studies have identified different dynamic factors that influence hospitals business development, there is always an increasing interest to find the best practices that ensure effective and sustainable marketing strategies in healthcare. The purpose of this study was to make an approach between patients and hospital managers to develop an effective marketing strategy for hospitals in Lebanon. A quantitative methodology was applied to statistically test both patients and managers’ attitudesthrough conducting two different simple surveys among patients and managers from fourdifferent hospitals in Lebanon. Self-administered questionnaires were designed in terms of marketing mix and hospitalization experience, and distributed randomly among participants to assess the implemented marketing strategies.Majority of patients were satisfied from the healthcare service provided and 93.3% of patients showed high level of loyalty to these hospitals. In terms of experiencing the marketing mix, majorityof patients were able to identify the most significant 7ps in hospitals especially in terms of price and people. Similarly, the results obtained from managers’ surveyshowed consistency of the marketing strategies applied by these hospitals with the patients’ attitudesbut with some conservation regarding the pricing strategies in the Lebanese healthcare system.The importance of healthcare marketing falls mainly in the framework of strengthening public relations with patients and maintaining a proper pricing strategy that is backed by the government and mediated by the guarantors. Future studies can be extended empirically in terms of geographical distribution of hospitals and the methodology applied.
Numerical computation of thermoelectric effiency of graphite sheet optimal dimension
Authors:   Laboratory of Applied Physics (LPA), Group of Mechanical, Thermal & Renewable Energies (GMTER),Lebanese University, Faculty of Sciences II, Dgheim J. , Chahine A. ,   Laboratory of Applied Physics (LPA), Group of Mechanical, Thermal & Renewable Energies (GMTER),Lebanese University, Faculty of Sciences II, Ghazeleh M. ,   Laboratory of Applied Physics (LPA), Group of Mechanical, Thermal & Renewable Energies (GMTER),Lebanese University, Faculty of Sciences II, Abdallah M. ,   Laboratory of Applied Physics (LPA), Group of Mechanical, Thermal & Renewable Energies (GMTER),Lebanese University, Faculty of Sciences II
Published: March 2021

Thermoelectric Graphite sheet has been studied numerically due to their ability to convert directly heat to electricity. Electro-thermal heat transfer equations coupling to initial and boundary conditions, are solved using finite difference and finite element schemes. The obtained results of both numerical techniques show good qualitative and quantitative agreements. In addition, the results of our numerical models present good conformity with the experimental result of Luo et al.. The voltage difference, the temperature variation, the Seebeck coefficient, the figure of merit and the maximum efficiency of graphite sheet are determined numerically. The ZT of the graphite sheet is calculated to be 1.27 at a temperature of 850 K for a graphite sheet surface of 0.26×0.25 cm2.
Analysis of Potential Drug-drug Interactions in Liver Cirrhosis Patients
Authors: Muti Annisa Farida , Anindya Chanica
Published: March 2021

Background: Patients with liver cirrhosis are at a high risk of drug interactions due to the use of multi-drug combination regimens. Objectives: This study analyzed potential drug-drug interactions in the liver cirrhosis patients at Gatot Soebroto Army Hospital, Jakarta in 2016. Material and Methods: This study employed an observational-cross sectional design with retrospective data collection of liver cirrhosis patients' medical records. The data of potential drug-drug interactions were identified using Drug Interaction Facts 2012 including the mechanism type, the severity and the onset of drug interactions. Results: As many as 88% of the liver cirrhosis patients experienced potential drug-drug interactions with a total of 35 cases. The highest proportions of the cases were found in the pharmacokinetic mechanism by approximately 25 cases (71.43%), minor severity comprising 29 cases (82.86%) and rapid onset by 19 cases (54.29%). The highest potential drug-drug interactions were furosemide-propranolol combination in 16 cases (45.72%). Conclusions: The high incidence of potential drug interactions in patients with liver cirrhosis requires high vigilance and close monitoring of all health professionals in achieving optimal therapeutic outcomes for the patients.