bluuebunny/crossref_metadata_2025 huggingface dataset:
Enkripsi Data Lokasi Menggunakan Algoritma Rivest Shamir Adleman dan Advanced Encryption Standard pada Location Based Services
Authors: Azzahra Yasmina , Hadiana Asep Id , Kasyidi Fatan
Published: February 2025

Location Based Services atau layanan berbasis lokasi (LBS) telah menjadi bagian penting bagi kehidupan sehari-hari. Keamanan data lokasi pada LBS menjadi perhatian utama karena data tersebut dapat digunakan untuk melacak keberadaan pengguna dan mengungkapkan informasi pribadi. Oleh karena itu, penggunaan algoritma kriptografi sangat penting untuk melindungi data lokasi pada LBS. Dalam penelitian ini, algoritma RSA dan AES digunakan untuk mengenkripsi data lokasi pada LBS. AES digunakan untuk mengenkripsi data lokasi, sedangkan RSA digunakan untuk mengenkripsi secret key AES. Namun, penggunaan RSA dan AES memiliki keuntungan dan kelemahan masing-masing yang perlu dipertimbangkan dalam memilih algoritma yang tepat untuk digunakan pada sistem LBS. Penelitian ini menunjukkan bahwa proses enkripsi dan dekripsi data lokasi menggunakan kombinasi 2 algoritma dapat dilakukan pada database sistem LBS. Hasil pengujian avalanche effect pada AES mendapatkan hasil yang baik dengan rata-rata nilai mencapai 50,78 %, sedangkan pengujian entropy mendapatkan hasil yang kurang baik dimana nilai entropy yang dihasilkan jauh dari nilai entropy yang berkualitas. Pengujian performa sistem juga dilakukan untuk melihat dan membandingkan waktu antara sistem dengan enkripsi dan tanpa enkripsi. Sistem yang diterapkan algoritma kriptografi mengalami peningkatan waktu dengan rata-rata mencapai 1,46 detik.
Tren Penelitian Metode Konsensus, Serangan, serta Pencegahannya pada Cryptocurrency Mining
Authors: Satrinia Dwina , Fajriyah Siti Zahrotul , Yutia Syifa Nurgaida
Published: February 2025

Studi ini membahas metode konsensus di cryptomining, serangan umum, dan pencegahannya. Blockchain awal menggunakan Proof of Work (PoW), yang tidak efisien energi dan rentan keamanan. Proof of Stake (PoS) dikembangkan untuk meningkatkan desentralisasi dan efisiensi energi. Protokol seperti Proof-of-Search (PoS) dan Proof-of-Publicly Verifiable Randomness (PoPVR) menawarkan alternatif PoW, mengatasi penipuan dan serangan denial-of-service. Penelitian ini juga mengevaluasi perilaku penambangan strategis dan metode deteksi serta pencegahan serangan. Model konsensus hibrida, seperti Hybrid PoW-PoS, menggabungkan kekuatan PoW dan PoS untuk melawan serangan mayoritas. Temuan menekankan perlunya keamanan yang kuat dan pemantauan berkelanjutan untuk mencegah aktivitas jahat dan memastikan keadilan serta keberlanjutan penambangan kripto. Makalah ini mengumpulkan analisis dari berbagai jurnal untuk meningkatkan keamanan dan efisiensi penambangan kripto.
Rancang Bangun Antena Mikrostrip Fraktal Dengan Rekonfigurasi Frekuensi Di Bawah 10 GHz
Authors: Veronica Veronica , Alaydrus Mudrik
Published: February 2025

Antena sangat penting untuk komunikasi. Dengan kemajuan teknologi dan kebutuhan manusia yang tidak terbatas, antena harus memiliki kemampuan yang lebih baik untuk berfungsi dalam berbagai kondisi propagasi. Contohnya, antena yang dipasang pada beberapa perangkat saat ini tidak dapat beradaptasi dengan berbagai kondisi lingkungan, terutama dalam hal komunikasi nirkabel. Untuk mengatasi masalah ini, dibangun sistem antena rekonfigurasi yang dapat bekerja pada berbagai frekuensi dan pola radiasi sesuai dengan layanan komunikasi yang dibutuhkan. Sistem antena rekonfigurasi memiliki kemampuan untuk menyesuaikan diri dengan perubahan lingkungan propagasi dengan mengubah frekuensi, polarisasi, dan pola radiasi kerjanya untuk memenuhi kebutuhan layanan yang akan digunakan. Dalam sistemnya, antena rekonfigurasi menggunakan switch untuk mengubah pola kerja yang diinginkan. Pada penelitian ini didapatkan hasil antena dengan 5 (lima) kondisi ON dan OFF nya masing-masing serta 3 (tiga) buah diagram radiasi gain yang berbentuk Unidirectional dan Omnidirectional. Dari hasil pengukuran diperoleh nilai S11 sebesar -10,1 dB sampai -28,1 dB dengan rentang frekuensi 1,37 GHz sampai 7,65 GHz, sedangkan yang diperoleh dari hasil simulasi nilai S11 sebesar -19,3 dB sampai -42 dB dengan rentang frekuensi 5,04 GHz sampai 8,96 GHz.
IMPLEMENTASI VLAN ROUTER ON A STICK MENGGUNAKAN GNS3 V2.2.23 UNTUK MENINGKATKAN PERFORMANSI JARINGAN KOMPUTER
Authors: Alkhoir Purnama , Nurhayati Ade , Fachrurrozi Nurwan Reza
Published: February 2025

Untuk mebuat jaringan yang handal, dikembangkan lah berbagai teknik khusus, seperti teknik subnetting dan penggunaan hardware yang lebih baik (antara lain switch dan router) maka muncullah konsep VLAN (Virtual Local Area Network). Agar antar VLAN dapat berkomunikasi dibutuhkan suatu jembatan yang berada pada lapisan OSI layer 3 yaitu router. Dengan menggunakan konfigurasi router “Router on a stick”, yang mana sebuah interface physical me-routing traffic antara beberapa VLAN pada satu network. Router interface dikonfigurasikan untuk beroperasi sebagai link trunk dan terhubung dengan sebuah port switch dalam mode trunk. Router menunjukkan inter-VLAN routing dengan menerima traffic VLAN yang telah di tag pada interface trunk dari switch dan secara internal merutekan antar VLAN menggunakan sub-interface.. Implementasi VLAN Router on a Stick dapat meningkatkan performansi jaringan computer dalam perkembangan jaringan computer kedepannya.
SISTEM DETEKSI DAN PEMANTAUAN PENCEMARAN UDARA BERBASIS IOT
Authors: Megantoro Andre , Saidah Sofia , Sevierda Raniprima
Published: February 2025

Berdasarkan Kementerian Lingkungan Hidup dan Kehutanan (2021), emisi kendaraan bermotor berkontribusi 70% terhadap polusi Nitrogen Oksida (NOx), Karbon Monoksida (CO), Sulfur Dioksida (SO2) dan Particulate Matter (PM) di daerah perkotaan. Penelitian ini bertujuan untuk mengukur kualitas udara dan pemantauan karbon monoksida dan gas amonia berupa alat deteksi dan pemantauan polusi udara berbasis IoT. Penelitian ini menggunakan metode penelitian System Engineering yaitu studi pustaka, analisis kebutuhan, desain sistem, pengembangan perangkat keras, pengembangan perangkat lunak, integrasi komponen, uji coba dan evaluasi, analisis data dan kesimpulan. Perangkat ini terdiri dari serangkaian sensor yaitu MQ-135, sensor MQ-7, Arduino Uno, ESP8266 sebagai alat yang terhubung ke internet dan perangkat lunak telegram. Data yang diperoleh dari sensor ditransmisikan ke Arduino Uno, kemudian ke ESP8266 secara nirkabel. Data pengukuran ditampilkan di kolom bot obrolan perangkat lunak telegram. Hasil penelitian menunjukkan bahwa sistem deteksi dan pemantauan udara berbasis iot menghasilkan deteksi beberapa parameter kadar gas CO dan NH3 pada beberapa objek, yaitu asap kendaraan, asap rokok elektrik, asap tembakau, dan parfum. Data kualitas udara yang diperoleh dari sensor dapat ditampilkan secara real-time melalui telegram dan disimpan dalam database. Sistem akan menampilkan peringatan "Tolong Gunakan Masker" yang muncul di aplikasi bot telegram ketika gas yang terindentifikasi melebihi ambang batas.
Keywords: Gas, Kualitas udara, Sensor MQ-135, Sensor MQ-7.
ANALISIS DAN DETEKSI SERANGAN SQL INJECTION PADA JARINGAN KEAMANAN PAYMENT GATEWAY
Authors: Erlangga Adhitya Bagus Putra , Yovita Leanna Vidya , Raniprima Sevierda
Published: February 2025

Keamanan sistem pembayaran elektronik melalui payment gateway sangat penting untuk menjaga integritas dan kepercayaan dalam transaksi finansial online. Dalam era digital, website top-up games menjadi komponen penting dalam industri game, namun sering menjadi target serangan, terutama melalui teknik SQL Injection. Penelitian ini bertujuan untuk menganalisis dan mendeteksi potensi kerentanan terhadap serangan SQL Injection pada sistem pembayaran elektronik.Metodologi penelitian melibatkan pengujian penetrasi menggunakan payload SQL Injection dengan pernyataan Data Manipulation Language (DML) dan Data Definition Language (DDL). Tujuannya adalah untuk memahami respons aplikasi terhadap serangan yang mencoba memanipulasi data di dalam database dan mengevaluasi apakah aplikasi memiliki lapisan keamanan yang memadai untuk melindungi struktur database. Hasil pengujian menunjukkan bahwa sistem memiliki mekanisme keamanan yang cukup efektif dalam mendeteksi dan mencegah serangan SQL Injection. Meskipun beberapa serangan berhasil, yang mengindikasikan adanya celah keamanan, sebagian besar serangan gagal berkat mekanisme keamanan yang ada. Hasil ini memberikan wawasan mendalam tentang kerentanan keamanan dan langkah-langkah mitigasi yang diperlukan untuk memperkuat keamanan sistem.
Keywords: Data, Database, Injeksi SQL, Keamanan Siber.
CYBER SECURITY IN THE INDIAN LEGAL SYSTEM: CHALLENGES AND A STUDY OF JUDICIAL INTERPRETATION
Authors: Annu Khan, Komal Audichya
Published: February 2025

The study explores important laws like the Information Technology Act of 2000 and Information Technology (Amendment) Act, 2008 as well as industry-specific rules and directives from organisations like the Indian Computer Emergency Response Team (CERT-In) and the Reserve Bank of India (RBI). Recent changes, such as the implementation of the Digital Personal Data Protection Act 2023, and its effects on cybersecurity, are given particular attention.
Adaptive Expertise and Meta-Competencies: A Cross-Industry Review of Critical Thinking, Emotional Intelligence, and Lifelong Learning
Authors: Takona James P
Published: February 2025

In the current workplace, it is crucial to possess a blend of traditional skills and adaptable knowledge founded on key meta-competencies like critical thinking, emotional intelligence, and lifelong learning. This research examines the importance of these meta-competencies in improving professionals' skills to manage the challenges of the modern workplace. The study emphasizes the importance of these skills in promoting innovation, adaptability, and resilience across different sectors by leveraging established theories and current research. It investigates the crucial role of incorporating these skills into educational and professional settings to equip individuals for the difficulties posed by a swiftly evolving global economy. By developing these vital skills, companies can prepare their employees to succeed in a fluctuating and unpredictable environment.
Reasons for decline and measures to promote Nili Ravi buffalo in its breeding tract
Authors: Gururaj M. , Ahuja Krishan , Tuteja F..C. , Saxena N.
Published: February 2025

The Food and Agricultural Organization (2000) termed buffalo as an important asset that is undervalued. Currently, there are 208 million buffaloes spread across 77 countries; the majority of the buffaloes are found in India (56.67%), followed by Pakistan (19.28%) and China (13.46%). India is endowed with a rich biodiversity of buffalo germplasm in the form of 20 recognized breeds and several distinct local types. Buffalo husbandry plays a crucial role in rural livelihood, food security, and the agricultural economy in India. Despite significant contribution to milk production, a decline in buffalo population was observed in dairy progressive states like Haryana and Punjab from 2012 to 2019, with a 28% and 22% decline, respectively. The breed-wise data revealed the highest decline in the Nili Ravi buffalo of 65%. The breeding area for Nili-Ravi buffaloes is located in the districts of Amritsar, Firozpur, Tarn Taran, and Gurdaspur in the state of Punjab, India. This decline in the buffalo population is alarming and calls researchers to find reasons for the decline in the Nili Ravi buffalo population and its breeding area, despite the breed performance being at par with any other milk-producing buffalo. In this regard, a study about the reason and extent of the buffalo population decline in the Punjab was carried out. For the study, 180 dairy farmers from Hoshiarpur (31.99%), Taran Tarn (30.76%), and Firozpur (29.62%) districts were selected purposively, where the highest decline in buffalo population was reported. Milk production performance, family pride and docile nature were the main reasons for most (~70%) of the selected farmers to keep Nili Ravi buffalo. However, frequent reproductive problems, less resale value, and off-breed characteristics (white patches) were the primary reasons that forced dairy farmers to shift from Nili Ravi to Murrah buffalo. Although both the Murrah and Nili Ravi breeds have similar productive and reproductive parameters, the Murrah buffalo breed is gaining popularity due to its higher resale value and a lack of associated cultural constraints. Thus, it is suggested to incentivize the Nili Ravi buffalo owners by introducing milk recording programs, improving the supply of superior germplasm for this vital breed, and addressing reproductive problems through awareness campaigns and training programs in convergence with research institutes and state animal husbandry departments, to propagate and conserve the Nili Ravi buffalo breed in the state.
Floristics and physical structure of five Amazon plots in Ecuador and Peru
Authors: Myster Randall
Published: February 2025

The Amazon contains some of the most important forested ecosystems on earth and so we need to know the nature and degree of their similarities and differences. Therefore I compared the floristics and physical structure of five common Amazonian forest-types (terra firme, palm and white sand [all unflooded], várzea and igapó [both flooded]) with data from separate one ha plots in the Ecuadorean and Peruvian Amazon. I found (1) the most abundant families were Arecaceae, Fabaceae, and Clusiaceae and those families along with Euphorbiaceae were the only families found in all five plots, (2) the highest stem density, the greatest number of large stems and the most closed canopy were in várzea and terra firme, (3) palm had the most median stems and the smallest average stem size, and (4) igapó had the smallest basal area and above-ground biomass. Ordination on the five plots then suggested that Arecaceae and Clusiaceae best defined the floristic data, and total stems and smallest stem size class best defined the physical structure data. Cluster analysis after ordination (1) based on floristics, showed that terra firme, várzea and igapó formed a cluster and both palm and white sand were in separate clusters by themselves, and (2) based on physical structure, showed that terra firme and palm formed a cluster, white sand and igapó formed a cluster and várzea was in a cluster by itself. While results suggest that soil characteristics are important in determining the floristic composition of Amazon forests and flooding characteristics are important in determining their physical structure, they can only set-up hypotheses to test by future sampling of these forest-types elsewhere in the Amazon
Abundancia espacio-temporal de renacuajos de Gastrotheca riobambae (Anura: Hemiphractidae), y comentarios sobre los cambios en el hábitat, Andes norte, Ecuador
Authors: Ramírez-Jaramillo Salomón
Published: February 2025

La rana marsupial Gastrotheca riobambae es una especie endémica que posee poca información sobre su población larval dentro de paisajes bajo presión antrópica. Se plantea cuantificar la abundancia poblacional de G. riobambae en dos sitios de muestreo ubicados en un valle interandino de Quito, y evidenciar los cambios ocurridos en el paisaje. Entre 2005 y 2013 en dos sitios de la Parroquia de Amaguaña, durante la época lluviosa se registraron en dos tipos de charcas temporales los renacuajos que se puedan obtener durante 50 minutos entre las 10:00 y las 13:00h. Los registros fueron analizados empleando la media aritmética y la desviación estándar. Para evidenciar cambios en el paisaje y el avance de la urbe, colocamos imágenes satelitales de los años 2008, 2014 y 2022. Las charcas de Santa Isabel presentan más fango, mientras que en El Ejido no. Se aplicaron técnicas de muestreo adaptadas para cada tipo de charca. Registramos 918 renacuajos, de los cuales 254 fueron para Santa Isabel y 664 para El Ejido. La mayor abundancia se registró en El Ejido, donde la charca no presenta fango. Las imágenes históricas evidencian el cambio en el paisaje y un notable avance de la urbe.
Pengembangan Media Panda (Papan Perbandingan) Berbasis Artificial Intelligence Materi Perbandingan Bilangan Kelas II SDN Cepoko Kota Semarang
Authors: Ningtias Liana Anggi Dwi , Witanto Yuli
Published: February 2025

Penelitian ini bertujuan untuk mengembangkan media pembelajaran berbasis kecerdasan buatan, mendeskripsikan hasil uji kelayakannya oleh validator ahli, dan menguji keefektifan produk media. Penelitian ini menggunakan jenis penelitian pengembangan atau Research and Development R&D) dengan model pengembangan ADDIE melalui lima tahapan berikut, Analysis (analisis), Design (perancangan), Development (pengembangan), Implementasion (implementasi), dan Evaluation (evaluasi) khususnya pada topik perbandingan bilangan untuk siswa kelas II. Analisis kebutuhan yang telah dilakukan, peneliti menemukan bahwa siswa kelas II di SDN Cepoko, Kota Semarang, mengalami kesulitan dalam memahami dan membedakan tanda perbandingan bilangan. Hal ini mengakibatkan mereka mengalami kendala dalam menentukan tanda perbandingan dengan tepat. Penelitian ini mengembangkan media pembelajaran yang berbasis Artificial Intelligence pada materi perbandingan bilangan untuk kelas II. Subjek penelitian dalam penelitian ini adalah peserta didik dan guru kelas II SDN Cepoko Kota Semarang. Teknik analisis data yang digunakan dalam penelitian ini meliputi uji normalitas, uji T-test, dan uji N-gain. Hasil penelitian menunjukan bahwa produk media yang dikembangkan layak dan efektif untuk digunakan sebagai media pembelajaran. Hal tersebut dibuktikan dengan diperolehnya presentase kelayakan sebesar 90% dari validator ahli materi dan 95,5% dari validator ahli media dengan kategori sangat layak. Media Panda (Papan Perbandingan) berbasis Artificial Intelligence juga mendapatkan tanggapan yang sangat positif dari guru dan peserta didik sebagai pengguna media, selain itu media Panda (Papan Perbandingan) berbasis Artificial Intelligence juga menunjukan adanya peningkatan hasil pretest dan postest yang diperoleh peserta didik.
Efektivitas Model Problem Based Learning Bermetode Eksperimen dengan Media PAREPIA untuk Meningkatkan Pemahaman Konsep IPAS Materi Sistem Pernapasan Manusia
Authors: Lathifa Fadhilah Wirda , Fakhriyah Fina , Khamdun Khamdun
Published: February 2025

Pemahaman terhadap suatu konsep sangat penting dalam membentuk pemikiran siswa. Namun, hal berbeda terjadi di kelas V SD Negeri 1 Gemiring Kidul, dimana rata-rata pemahaman konsep IPAS peserta didik tergolong rendah. Rendahnya pemahaman konsep IPAS tersebut didasarkan pada hasil tes studi pendahuluan dengan perolehan rata-rata sebesar 58,66. Selain permasalah tersebut, diperoleh permasalahan lain yaitu pelaksanaan pengajaran yang kurang variatif sehingga menyebabkan peserta didik bersikap pasif selama kegiatan belajar. Inovasi dalam pengajaran perlu diterapkan sebagai upaya meningkatkan pemahaman konsep IPAS peserta didik. Salah satu cara inovasi pengajaran yaitu pelaksanaan pengajaran menggunakan model Problem Based Learning (PBL) bermetode eksperimen dengan bantuan media PAREPIA (Papan Respirasi Manusia). Penelitian ini bertujuan untuk (1) menganalisis perbedaan rata-rata pretest dan posttest peserta didik, dan (2) menganalisis peningkatan pemahaman konsep IPAS peserta didik. Siswa kelas V di SD Negeri 1 Gemiring Kidul terdiri dari 23 siswa yang dipilih sebagai sampel penelitian ini. Penelitian kuantiatif pada penelitian ini menggunakan pre-eksperimental one group pretest-posttest design. Data yang digunakan peneliti diperoleh dari hasil observasi, wawancara, tes, dan dokumentasi dengan pengujian uji normalitas, Paired Sample T-Test, dan N-Gain. Hasil penelitian diperoleh rata-rata pretest sebesar 47,13 meningkat menjadi 87,78 pada rata-rata posttest dan hasil Sig. (2-tailed) 0,000 kurang dari 0,05. Peneliti juga memperoleh hasil uji N-Gain Score 0,7668 (tinggi) dan N-Gain Percent 76,68% (efektif). Diperoleh kesimpulan bahwa (1) rata-rata pretest dan posttest pemahaman konsep IPAS materi sistem pernapasan manusia memiliki perbedaan, dan (2)  pemahaman konsep IPAS peserta didik meningkat.
Lagorio’s Wall in the Crimea: pages of scientific activity of the geologist Oleksandr Lagorio
Authors:   National Museum of Natural History, NAS of Ukraine (Kyiv, Ukraine), Mikhalenok Dmytro
Published: February 2025

The paper presents selected pages from the biography and scientific activity of the world-famous geologist Oleksandr Lagorio (1852–1944). The formation of the Lagorio’s scientific views in the universities of Dörpt (now Tartu, Estonia) and Warsaw (now Poland) are shown. In the latter, a wide profiled scientific school of the scientist was formed, including synthetic geology (experimental mineralogy and petrography)—the most well-known representative of which was the Polish scientist Józef Morozewicz, crystallography (Georg Wulff), and applied and theoretical geology (Dmitro M. Sobolev). First published is the letter to V. I. Vernadsky (dated to 30 December 1893) with a request to provide care for his students. The information presented provides further details to the biography of all those mentioned in the letter. Lagorio studied the processes of magma differentiation—Lagrio’s rule is now well-known in petrography. His research laid foundation for the physicochemical direction in petrography. In the Crimea, in various years between 1877 and 1897, the scientist studied the outcrops of igneous rocks considering their active influence on the formation of the relief. His theoretical views on the relations between igneous rocks and tectonics remain relevant until these days. All outcrops of igneous rocks were attributed to one magmatic centre, and the scientist estimated their age as Upper Jurassic–Lower Cretaceous. In the Crimea, the scientist first discovered granites, schists, the rock taurit, the mineral natrolite, etc. Details of the scientist’s excursion to Kara-Dag (published in French), which took place in September 1897, with participants of the VII International Geological Congress are presented: it was the first presentation of geological objects as an open-air museum to the scientific community. During the excursion, the scientist drew particular attention to a picturesque, large and majestic dyke. In the scientific literature and toponymy of the early 20th century, the dyke was called Lagorio’s Wall as a tribute to the outstanding geologist, native and researcher of the Crimea, whose scientific ideas continue to fascinate researchers. Details of an excursion to the Crimean Mountains also led by Oleksandr Lagorio are briefly described. The two excursions laid the foundation of international scientific tourism to the Crimea. The scientist’s views on the age of igneous rocks were confirmed by other domestic researchers and have been further developed in geological science.
Pengaruh Gaya Hidup, Varian Produk Dan Layanan Terhadap Keputusan Pembeli Di Lucha Coffe Medan Johor
Authors: Batubara Mutia Syahreza , Syafina Wan Dian , Hidayat Toni , Siregar Horia
Published: February 2025

The purpose of this study was to analyze lifestyle, product variants and services affect buyer decisions at Lucha Coffee Medan Johor. This type of research is quantitative. The population in this study were 390 people who made purchases at Lucha Coffe Medan Johor which were taken from data in April 2024. In this study, the sample was taken using the Slovin formula, and using random sampling techniques. So, the total number of respondents in this study was rounded up to 80 consumers who made purchases at Lucha Coffee Medan Johor. The research instrument used a questionnaire with a Likert Scale data measurement scale. The data analysis technique uses validity, reliability and classical assumption tests. The data analysis method uses multiple linear regression with the help of the SPSS program. The results of this study indicate that partially lifestyle has a positive and significant effect on purchasing decisions at Lucha Coffee Medan Johor. Product variants have a positive and significant effect on purchasing decisions at Lucha Coffe Medan Johor. Service has a positive and significant effect on purchasing decisions at Lucha Coffee Medan Johor. In addition, lifestyle, product variants and service simultaneously (simultaneously) affect the purchasing decision variable at Lucha Coffe Medan Johor with a value of Fcount (58.744) > Ftabel (2.72), and a significance value of 0.000 <0.05.
Faktor-Faktor yang Mempengaruhi Sikap Pengguna terhadap Teknologi Cashless pada Generasi Z Di Indonesia
Authors: Sanapang Gracela Marisa , Kohar Felicia , Nurtani Leony Putri , Santoso Robin Christoffel
Published: February 2025

This study aims to explore the factors that influence user attitudes towardscashless technology in Indonesia. The increasing adoption of cashless payment systemsis essential to understand the elements that shape positive user attitudes. This studyuses a quantitative approach, analyzing the influence of Perceived Usefulness,Perceived Ease of Use, Trust in Technology, and Perceived Risk on cashless userattitudes. The respondents in this study were 385 from generation Z. Data werecollected by providing a series of structured questions through a survey involvingrespondents who use cashless technology, and multiple linear regression analysis totest the proposed hypothesis. The results of the study indicate that perceived benefitsand ease of use have a significant positive impact on user attitudes, while the level oftrust and risk perception also have an effect, but with different complexities. Thesefindings provide insights for technology developers and stakeholders to design moreeffective strategies in increasing the adoption of cashless technology in society. Thisresearch is expected to contribute to the development of a more inclusive and efficientpayment ecosystem.
Pengaruh Motivasi, Budaya Organisasi, Produktivitas Dalam Peningkatan Kinerja Pegawai Di UPTD PJU
Authors: Esse Andi
Published: February 2025

This research aims to determine the impact of Work Motivation, Organizational Culture, and Work Productivity on the performance of employees at UPTD PJU in Parepare City. This is a quantitative study with the subjects being the employees at the UPTD PJU office in Parepare City. The sampling in this study uses the census sampling technique, where all members of the population are used as samples, involving a total of 96 employees as research samples. Data collection was conducted using a questionnaire, which was then analyzed using path analysis. The results of this study indicate that in the first path or sub-structural model, Work Motivation, Organizational Culture, and Productivity have a significant effect on Performance both simultaneously and partially. The results of the second path or sub-structural model also show that Work Motivation, Organizational Culture, and Productivity have a significant effect on Work Performance both simultaneously and partially.
Pengaruh Kebutuhan Sosial dan Budaya Kerja Terhadap Kepuasan Kerja
Authors: Isra Muh , Herniah Herniah , Normiyati Normiyati
Published: February 2025

This research is a quantitative descriptive study that aims to analyze the effect of social needs, work culture on job satisfaction at PT Aneka Jasa Sorowako in Makassar. This study uses primary data obtained by distributing questionnaires to 36 respondents. To analyze the data, the authors used multiple linear regression analysis tools. Based on the results of calculations using the SPSS program, it was found that the t value was 4.281 for the social needs variable. Meanwhile, the work culture variable found a t value of 5.545 with a significance value of 0.001 for each variable. This shows that social needs and work culture have a positive and significant effect on employee job satisfaction.
Impact of reviews in e-commerce platforms on customer behavior: A case study of the Arab market
Authors: Helmy Yehia Mostafa Kamal , Abdou Shereen Aly Hussien Aly
Published: February 2025

The study investigates the impact of electronic reviews (e-reviews) on consumer purchasing behavior in Arab markets, considering the moderating role of customer characteristics. It is based on a sample of 490 participants from seven countries, including Bahrain, Egypt, Jordan, Kuwait, Qatar, Saudi Arabia, and the UAE, with equal weighting for each market in the second quarter of 2024. The study uses a comprehensive questionnaire based on a 5-point Likert scale and analyzes data using descriptive and inferential statistics, including ANOVA and hierarchical regression. The study found a significant positive correlation between e-reviews and online purchasing behavior. The results highlight the importance of demographic characteristics in moderating the relationship between e-reviews and consumer behavior. The findings suggest that younger consumers, females, and those with higher educational levels tend to place greater importance on e-reviews when making purchasing decisions. The study provides implications for marketers and researchers in future studies.
The relationship between financial intermediation development and poverty levels: An empirical analysis
Authors: Vladimirovich Turyan Karen
Published: February 2025

Financial intermediaries are an important part of the financial infrastructure of the country's economy, which is aimed primarily at satisfying the needs of the population. Poverty, in a broad sense, is a condition incompatible with the satisfaction of all needs. Thus, financial intermediation, by its nature, carries a toolkit that prevents the spread of poverty. A poor person is not a consumer of financial services, which encourages intermediaries to improve the welfare of citizens to increase the demand for services. The dependence of the poverty level on the development of financial intermediation is of high importance for addressing the challenges faced by developing economies. The purpose of this research is to study the directions of the relationship between the development of mediation and the level of poverty based on an empirical analysis of data on the development of the economies of post-Soviet countries. The author substantiated the need to combine private and public efforts in solving the problems of developing financial intermediation and reducing poverty. It is necessary to maintain a balance of individual and public interests when developing a policy for the development of financial intermediaries.
Development of an intelligent platform for predicting curriculum management in higher education under the AUN-QA framework
Authors: Tumthong Suwut , Samakthai Nichanun , Tasatanattakool Pinyaphat
Published: February 2025

This research aims to study and define the user requirements and operational capabilities required to develop an intelligent platform for forecasting and managing higher education courses under the AUN-QA framework using documentary research, platform design, and technology suitability assessment. The samples studied include personnel, instructors, course administrators, and IT specialists selected by the purposive method. Data were analyzed using statistics and standard deviation calculations. The results show that the developed platform should have five main components: user data control with AWS IAM and React, access security, SmartEduQA system for data storage and analysis, data presentation with Microsoft Power BI, and a serverless storage system. The platform is designed to meet the needs of administrators in forecasting the labor market and managing courses, instructors in analyzing data according to AUN-QA standards, and staff in managing data quickly and supporting interactive display. This platform can help make higher education course management efficient and aligned with AUN-QA standards.
Corrosion Mitigation with Chemical Injection in Welded Carbon Steel Pipe for Offshore Water Treatment Plant
Authors: Mgbemere Henry Ekene , Agunsoye Johnson Olumuyiwa , Ojemeni Kenechi Ijeoma , Izuegbu Obianuju Vivian
Published: February 2025

In Floating, Production, Storage, and Offloading (FPSO) vessels, the steel pipes used for water treatment plants are susceptible to corrosion from dissolved oxygen and bacteria in seawater. Chemicals such as oxygen scavengers and biocides are used to combat this. However, using oxygen scavengers can lead to bacterial growth, which can cause a reduction in pipe diameter, increased water pressure, and potential leaks, particularly in the welded sections. Biocides are used to address bacterial growth. In this study, steel coupons were welded with a low-hydrogen electrode, and water from the Lagos lagoon was used to replicate seawater composition. The study employed two different media, agitated and non-agitated, to investigate the effect of water flow dynamics on corrosion rate. Chemical injections did not effectively mitigate corrosion in the tested conditions but sometimes increased it. The results revealed that general corrosion was observed in the samples when no chemical was injected into the system, with an average 0 mm/yr corrosion rate. The agitation of the media led to increased corrosion rates. For biocide injection, the rate increased from 1 mm/y to 2 mm/yr, while in oxygen scavenger solution, the rate increased from an average of 4 mm/yr to 8 mm/yr. Analysis of the cultured seawater parameters showed variations in salinity, total dissolved solids, oxidation-reduction potential, pH, temperature, specific gravity, and conductivity across different media.  The pH of the solution generally increased with time, while the addition of an oxygen scavenger reduced the pH value from approx. 6.5 to 6.2. Agitation of the media and chemical injection increased the conductivity of the solution. Biocide introduction lowered the redox potential, while oxygen scavenger made the redox potential unstable. X-ray diffraction analysis of the steel surface exposed to the seawater indicated the presence of various compounds, suggesting ongoing corrosion processes and the existence of organic and inorganic contaminants. This research has the potential to significantly impact offshore water treatment, providing valuable insights into the challenges and potential solutions for corrosion mitigation in this critical area.
Vaccine therapies for cancer: challenges and strategies
Authors: Gong Rui
Published: February 2025

Vaccine refers to the biological products that can make the body immune to specific diseases after inoculation and refers to biological products made with various pathogenic microorganisms for preventive vaccination. Vaccine is an effective means of disease prevention, especially for the control of epidemic diseases and infectious diseases play a vital role. Vaccines are mainly used to attenuate and inactivate pathogenic microorganisms, which can reduce their harm while retaining the ability of pathogens to stimulate organisms to produce immune responses. By injecting the vaccine, the organism can produce a specific immune response to the pathogenic microorganism, and the corresponding immune response can be quickly generated when it is exposed to the pathogenic microorganism again. Vaccination is a simple, safe and effective way to train a person's immune system to produce antibodies that can protect people from harmful diseases before they are even exposed to them. Vaccination uses the body's natural defense mechanisms to build resistance to specific infections and boost a person's immune system. In addition to preventing disease, vaccines are increasingly being used to treat cancer. Cancer vaccines, as part of cancer immunotherapy, can recognize specific proteins on cancer cells, stimulate the immune system, kill existing cancer cells and prevent cancer from continuing to develop. This review summarizes the types, clinical applications and development of cancer vaccines, and discusses the advantages and disadvantages of cancer vaccines as well as the opportunities and challenges for their future development.
The Potential of Therapeutic Vaccines and Antibodies against Parkinson's Disease
Authors: Gu Mengyu
Published: February 2025

Parkinson's disease is the second largest neurodegenerative disease after Alzheimer's disease. There are about 6.3 million Parkinson's patients worldwide. With the worldwide trend of population aging, increasingly elderly people will face the risk of suffering from Parkinson's disease. However, the existing drugs can only alleviate the symptoms to some extent and are often accompanied by drug resistance and serious side effects, so more effective treatment methods are needed. In recent years, scientists have realized the immense potential of immunotherapy for neurodegenerative diseases. More studies about vaccines and monoclonal antibodies for Parkinson's disease have been reported, and the results are worthy of discussion and consideration. This paper summarizes two preclinical studies on prophylactic vaccines and three clinical trials on monoclonal antibodies against Parkinson's disease, with a discussion about their advantages and disadvantages. Additionally, this paper summarizes the two main challenges of the application of immunotherapy in Parkinson's disease, which are how to reduce the adverse effects and how to ensure the macromolecules penetrate the blood-brain barrier.
CRISPR/Cas9 Application in CAR-T Cell Based Tumor Therapies
Authors: Liu Zhirui
Published: February 2025

The CRISPR/Cas9 system is an essential tool for treating cancer. In this paper, CRISPR/Cas9 homogenic orientation repair (HDR), NHEJ (NHEJ) and the DNA repair mechanism are discussed in this paper. Furthermore, CRISPR/Cas9 has been applied to CAR-T cells genetically modified, focusing on improvements in expression, survival, and the manner in which CAR-T cells operate, as well as their success against cancer cells. This article, we review CAR-T therapeutic approaches and their challenges in both solid and hematological malignancies. Utilizing CRISPR/Cas9 can address this issue by optimizing CAR structure, enhancing cell survival and enhancing CAR-T targeting ability. Problems related to cytotoxicity, targeting specificity, and safety remain. In this article, we suggest the optimization of CRISPR/Cas9 transmission, selection of appropriate target genes, and implementation of security surveillance and assessment. To conclude, CRISPR/Cas9 therapy may enhance efficacy and offer promising prospects for CAR-T carcinoma. But more research and experience is needed to make sure that it is safe and effective.
Current Progress of CAR-T Cell Therapy in Lung Cancer
Authors: Lou Jingzhao
Published: February 2025

Lung cancer is one of the most common malignancies in the world. For lung cancer treatment, traditional surgery, radiotherapy, chemotherapy, monoclonal antibody therapy and other therapeutic methods can have a certain therapeutic effect, but the prognosis of these treatment methods is generally poor. The recurrence rate of patients treated with surgery is high, and chemoradiotherapy may cause damage to normal cells and tissues with serious side effects. Drug resistance is also a very serious side effect when using monoclonal antibody drugs. So, a better treatment is needed. CAR-T has been investigated in the past as a potential treatment for lung cancer. CAR-T for lung cancer is now undergoing clinical testing. Finding viable therapeutic targets is essential for CAR-T therapy for lung cancer, and there are numerous antigenic targets for this type of treatment. The advancement of CAR-T therapy, its relevant targets for lung cancer treatment, and the shortcomings of traditional methods will be discussed in this review.
CRIPSRi: a promising RNA-guided CRISPR-dCas Technology for Alzheimer’s Disease and Glioma Therapy
Authors: Lu Yuhan
Published: February 2025

The escalating prevalence and mortality rates of neurological disorders, such as Alzheimer's disease (AD) and glioma, pose significant healthcare challenges. The exploration of novel therapeutic modalities is in urgent need. Among these, CRISPR interference (CRISPRi) leveraging RNA-guided deactivated Cas proteins for the regulation of gene expression stands out for its potential in neuroepigenetic interventions. This paradigm shift from the canonical CRISPR-Cas9 system, which operates via the introduction of double-strand breaks, to CRISPRi's non-cleaving approach mitigates the risk of off-target mutagenesis, thereby presenting a more refined strategy for modulating gene activity within the intricate milieu of the central nervous system (CNS). This review highlights the shift from CRISPR-Cas9 to CRISPR-dCas technologies, focusing on the application of CRISPR interference in addressing the pathogenesis of AD and glioma. The pathological frameworks is further unpacked by revealing the pivotal roles of genes such as APP, MGMT, and TERT. Through allele-specific epigenome editing, CRISPRi has demonstrated considerable efficacy in the preclinical modulation of gene expression via targeted DNA methylation, consequently degrading the pathological manifestations. Notably, evidence suggests CRISPRi's capacity to effectuate significant downregulation of hotspot genes like APP and MGMT expression and to modulate TERT activity. Despite promising results, challenges such as off-target effects, delivery barriers, particularly across the blood-brain barrier (BBB), and potential immunogenic responses limit clinical translation. Advances in sgRNA design, novel delivery systems, and epigenetic editing tools are discussed as strategies to overcome these hurdles. Thus, CRISPRi can be positioned as one of the most promising instruments in genomic medicine, with the potential to reshape the therapeutic strategies of AD and glioma.
Selection and Application of Targeted Therapy in Breast Cancer
Authors: Shen Lilian
Published: February 2025

Breast cancer remains a major global health problem, with high mortality and morbidity rates among women worldwide. Breast cancer has diverse molecular and genetic characteristics and therefore requires personalized treatment strategies to improve patient prognosis. Targeted therapies have become the cornerstone of breast cancer treatment, targeting molecular signaling pathways and receptors involved in tumor growth and progression. The present state of targeted treatment for breast cancer, encompassing the disease's triple-negative (TNBC), human epidermal growth factor receptor 2-positive (HER2+), and hormone receptor-positive (HR+) subtypes, is thoroughly reviewed in this article. We'll go over the reasoning for choosing targeted treatments (such tyrosine kinase inhibitors, PARP inhibitors, and monoclonal antibodies) in light of tumor-specific indicators and genetic changes. In addition, the clinical use of these therapies is analyzed, focusing on their integration with treatment regimens, impact on survival, and management of treatment-related side effects. The review also emphasizes the growing importance of biomarkers to guide therapy decisions, the importance of targeted therapeutic resistance mechanisms, and the potential for novel drugs and combination therapies.
Exploring the Molecular Mechanisms of the ERK/MAPK Pathway in Melanoma Development
Authors: Chen Danyang
Published: February 2025

Although melanoma is a less prevalent form of skin cancer, its malignancy is rather high. Specifically, malignant granulocytic melanoma has emerged as one of the most common causes of mortality from skin cancer. Melanoma patients have a good prognosis as long as the cancer is identified and treated early in the disease. However, as the cancer spreads, it becomes more aggressive and metastasizes, making treatment more challenging. In recent years, scientists have conducted in-depth studies on the molecular mechanisms of cancer development and progression, and have discovered many signaling pathways associated with cancer progression. Among them, the ERK/MAPK pathway has been confirmed to be one of the key signaling pathways in a variety of cancers. This paper reviews the mechanism of the ERK/MAPK pathway in tumor progression and focuses on its function in melanoma. This article highlights the significance of therapeutic approaches that target this route in the treatment of melanoma by offering insights into it. These insights may offer crucial hints for the creation of therapeutic methods that target this pathway. These treatment approaches might involve the creation of drugs that specifically target important pathway molecules as well as the use of technologies like gene editing to control the pathway's activity.
The Application and Effectiveness of CRISPR-Cas9 in Alzheimer's Disease and Parkinson's Disease
Authors: Wang Yubu
Published: February 2025

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are both types of neurodegenerative diseases (ND) that lead to severe failure in the nervous system. Usually, AD and PD are caused by genetic or environmental factors, and patients of AD or PD suffer from life inconveniences. AD and PD are both the major causes of irreversible dementia and can be classified into familiar and sporadic. A greater proportion of patients get sporadic AD and PD, and there hasn’t been an effective treatment for the diseases. Widely discussed in the 21st century, it is believed that CRISPR-Cas9 gene therapy may be a possible potential treatment for AD and PD because CRISPR-Cas9 is a such strong genetic modification tool. This passage summarizes papers from the past 5 years to demonstrate the mechanisms of AD and PD, and how these mechanisms related to the applications of CRISPR-Cas9 gene therapy. Also, the benefits and drawbacks of the therapy are discussed in detail.
Research Progress on the Mechanisms of Autophagy in Hepatocellular Carcinoma
Authors: Zhu Chizheng
Published: February 2025

Autophagy, a cellular breakdown process, has two distinct roles in the progression of cancer: nutrition still furthers this; it is either a hindrance or propelling to tumor growth. Autophagy is the process of recycling cellular waste and is tightly controlled at the molecular level in hepatocellular carcinoma hepatocellular carcinoma (HCC). Through the process of consideration, the mechanisms (mTOR and AMPK pathways) along with the Beclin-1/Vps34 complex are distilled. The other main thing we touch on is how the cell sees the absence of a normal covert that leads to cancer cells. Due to the recent scientific and research milestones, autophagy has been proven to have its own genes and pathways, which form its characteristic in HCC. Thus, these discoveries have addressed areas leading to the identification of novel therapeutic targets therapeutically. Moreover, in this article, the clinical ramifications of autophagy in HCC are discussed. The implications of autophagy as a predictive factor, along with identified fetters and broadening frontiers in the employment of autophagy as a potential drug for the treatment of cancer, are involved. The purpose of the research is to pinpoint the complexity of autophagy in cancer treatment scope, as well as reveal unaddressed topics and focus the effort on the improvement of cancer treatments. This is accomplished by describing the current autophagy information related to HCC and the progress achieved in autophagy research regarding HCC. This review provided an overview of what was accomplished in the autophagy research process.