bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental study on corner filling of B1800HS boron steel tubes in hot gas forming-quenching integrated process
Authors: Ruan Xianggang , Hu Xinyu , Xu Yi , Zhao Lidong , Cheng Chao , Han Fei , He Zhubin
Published: February 2023

The adequate filling and quenching of small corner features are major challenges in the hot gas forming-quenching integrated process to manufacture complex-shaped boron steel tubular parts. As the filling and quenching of small corners occurs at the later stages of pressurized bulging, the temperature of the non-contact zone on the tube may rapidly reduce below the required forming temperature. Considering the tube forming process involves closed and invisible features, a single-sided die quenching experiment for B1800HS boron steel sheets was designed to simulate the in-die quenching process of steel tubes. Moreover, the cooling rate and hardness distribution of the die-contact and non-contact zones were analyzed. Specific bulging experiments for variable diameter tubular parts with axial corner were performed. The effects of bulging temperature and pressurizing rate on corner filling, microstructure, and mechanical properties were studied. The results confirmed that for a given thickness of B1800HS sheet, regions of rapid cooling rate and martensite transformation occurred under a smaller diameter of the non-contact circular zone. For the sheet with a thickness of 1.4 mm, when the diameter of the non-contact circular zone was reduced to lower than 20 mm, the complete martensitic transformation of the entire sheet could be realized. For the boron steel tubes, the filling of the axial corner was significantly improved with the increase of the initial bulging temperature and the gas pressurizing rate. At the initial bulging temperature of 900 °C, when the pressurizing rate increased from 1 MPa/s to 3 MPa/s, the obtainable minimum corner radius decreased from 24 mm to 16 mm. The width of the non-contact zone was less than the diameter (15 mm) that can achieve complete martensitic transformation in the single-sided die quenching experiment; therefore, a sufficiently high cooling rate can be obtained. However, when the pressurizing rate increased from 3 MPa/s to 5 MPa/s, the obtainable minimum corner radius only decreased from 16 mm to 12 mm. The limited filling of the corner was the result of a significant temperature drop during hot gas forming. Decreasing the cooling rates of the tube or increasing the pressurizing rates during the hot forming stage can extend the range of reasonable process parameters in the hot gas forming-quenching integrated process of the boron steel tubes.
New congruences for broken k- diamond partitions
Authors: Yu Jing-Jun
Published: February 2023

Broken k-diamond partitions were introduced by Andrews and Paule. Let Δk(n) denote the number of broken k-diamond partitions of n. In 2015, By using the throey of Ramanujan’s theta function, Ahmed and Baruah established some congruences modulo 2 for Δ7(n). In this note, we continue to study the congruence properties of Δ7(n). By using the theory of modular forms, we generalize the congruences proved by Ahmed and Baruah. In addition, we also find two congruences modulo 2 for Δ23(n).
Terahertz Radiation Generation by Laser Interaction with a Periodic Array of GaAs Structure
Authors: . Sandeep , Malik Hitendra K
Published: February 2023

In the current study, a method for generating terahertz (THz) radiation using a GaAs structure array and transient current from a laser is proposed. The current generated across the length of these structures is responsible for the generation of THz radiation, where the entire system acts as phase-array dipole antennae. The maximum emitted THz power is achieved in the directions, where the conditions −bd/𝑐 𝑠𝑖𝑛𝜃𝑐𝑜𝑠𝜙=𝑝1𝜋 and −bd/𝑐 𝑠𝑖𝑛𝜃=𝑝2𝜋 are met; b and d are the widths and the length of a single GaAs structure and p1 and p2 are the integers. Where M1 and M2 are the numbers of GaAs structures along the longitudinal and transverse directions of the laser propagation, respectively, the overall antenna gain is observed to be M12 M22in these directions. The antennae approach used for the proposed GaAs periodic array enables us to obtain the THz profile in the frequency domain and realize the role of arrays and size of GaAs structure, making the emitted radiation suitable for its THz Time Domain Spectroscopic applications.
N-Formylation of Amines with CO 2 by Inorganic Ligand Support Ni Catalyst
Authors: Zhao Chengchun , Tao Chaofu , Xie Ya , Yu Han
Published: February 2023

N-formylation of amines with CO2 is a valuable approach to utilizing CO2 as a C1 source in organic synthesis. Herein we presented a highly efficient N-formylation of amines with CO2 and KBH4 catalyzed by (NH4)4[NiMo6O18(OH)6], which is composed of central Ni(II) core supported by MoVIO6 inorganic ligands, and provided corresponding formamides with good selectivity and yields for various primary and secondary amines under mild conditions. Moreover, primary diamines could also be efficiently formylated to afford diformamides. The catalyst could be recycled for six times without significant decrease in catalytic activity and used in gram-scale synthesis. Finally, the reaction mechanism was presented based on the related literature reports and control experiments.
pH-Responsive bio-erodible glipizide loaded PLA@GT-Dextran core-shell microspheres for antidiabetic drug delivery
Authors: Kumar Sumit , Bansal Smriti , Singh Ankita , Poddar Deepak , Sarkar Anjana
Published: February 2023

Hypoglycaemia and fast acting nature of glipizide makes it an effective antidiabetic drug but due to lack of sustainability of glipizide its usage is limited. Here, a pH responsive glipizide loaded PLA (poly (lactic acid)) microspheres were fabricated by emulsion solvent evaporation technique, which were coated with cationic derivative of dextran that exhibited significant pH sensitivity and mucoadhesive property due to presence of positively charged functional group that can readily interact with hydroxyl group present in the mucus lining via polar interaction. The fabricated core-shell microsphere possesses interconnected pores and constriction sites which control the release behavior of loaded glipizide and improve its efficiency. pH-responsive release behavior was evaluated by in-vitro drug release study at three distinct pH of 1.5, 7.4, and 9.2. The physiochemical characterization results confirmed that the glipizide was loaded within PLA microspheres and cationic dextran were present at its surface. The obtained core-shell microspheres possess an average particle size of 17.17 ± 1.33 µm with high drug encapsulation efficiency of 57.47 ± 2.7%. Due to presence of cationic dextran at microsphere`s surface, they possess high hydrophilicity as well as polar interaction with the mucus lining of stomach and also prevent premature release of drug in gastric media as indicated by contact angle measurement and confirmed by in-vitro release study at pH 1.5. A controlled glipizide release of 44.49 ± 11.01% was obtained at pH 9.2 within 48 hours.
A narrative inquiry into the cultivation of professional identity of medical students – through an online knowledge-sharing community
Authors: Li Shanshan
Published: February 2023

Cultivating medical talents with professional identity is the ultimate goal of medical education, yet there is a lack of long-term empiric data on the process of cultivation. This longitudinal narrative inquiry study collecting data from chat records, meetings and interviews involved a dynamic online knowledge-sharing community. Through focusing on the evolving characteristics of the online knowledge-sharing community and the changes in medical students’ dentities, this study utilized Clandinin and Huber’s framework to explore how students’ knowledge resonated with the group and developed in the online knowledge-sharing community, and during the process, how professional identity was cultivated in those pre-career years when professional growth opportunities were lacking. Fine-grained analysis showed that in a virtual community that overcame some barriers and formed multi-layered teacher-student relationships, medical students struggled to balance their self-identities and the professional identity by playing a proactive role and changing perspectives to share explicit and tacit knowledge, with blended interaction, facilitating strategies and the mentor’s role as influencing factors. The analysis also identified that the online knowledge-sharing community formed around originating events, with memories reconstuction and multi-layered interactions as the positive features of the way students engaged in online conversations to facilitate their professional identity. Online teacher-student knowledge-sharing communities provide an innovative approach to assisting professional identity formation. The study complements the literature about doctors’ online communities, knowledge sharing and the professional identity of medical students, and has important implications for medical education.
In-Situ Solar Tower Power Plant Optimization by
Differentiable Ray Tracing
Authors: Pargmann Max , Ebert Jan , Quinto Daniel Maldonado , Pitz-Paal Robert , Kesselheim Stefan
Published: February 2023

Solar tower power plants play a key role to facilitate the ongoing energy transition as they deliver
climate neutral electricity and direct heat for chemical processes. These plants generate temperatures
over 1000 °C by reflecting sunlight with thousands of mirrors (heliostats) to a receiver. The temper-
ature achievable in practice is limited due to the system’s susceptibility to small surface defects and
misalignments of individual mirrors, hindering the plant’s full efficiency. We present an inverse render-
ing technique that predicts the incident power distribution of each heliostat, including the inaccuracies,
based solely on focal spot images that are already acquired in most solar power plants. The method
allows reconstructing flawed mirror shapes within sub-mm precision. Applied at the solar tower plant in
Juelich, our approach outperforms all alternatives in accuracy and reliability. Our data-driven method
is a key ingredient to building digital twins of solar power plants. It can be integrated into the existing
infrastructure and plant control at low cost, leading to increased efficiency of existing and decreased
expenses for future power plants, the key factors of success in the competitive market. For other
fields, our approach can be a blueprint, as we present the option for the very first large-scale indus-
trial deployment of differentiable ray tracing. Merging data-intensive Machine Learning with physical
modeling creates flexible, data-efficient and trustworthy solutions applicable in science and industry.
THYROID DISORDERS IN NORTH INDIA AND THEIR REPORTING BY BETHESDA SYSTEM Â€“ 1 YEAR RETROSPECTIVE STUDY
Authors:   Senior Resident Department of Pathology GMC Jammu., Rani Rekha , Gupta Ishani ,   Senior Resident Department of Pathology GMC Jammu., Gupta Jyotsna ,   Professor Postgraduate Department of Pathology GMC Jammu., Kumar Anil ,   Senior Resident Department of Surgery GMC Jammu.
Published: February 2023

Background: Thyroid nodules are very common clinical problem and thyroid cancer is becoming more prevalent. Fine needle aspiration cytology (FNAC) has become a well established modality in the diagnosis, staging and follow up of thyroid nodules. FNAC results are routinely classified using the Bethesda system for reporting thyroid cytopathology. The Bethesda system for reporting thyroid cytopathology is a significant step to standardize the thyroid FNA reporting. It has high reproducibility, predictive value and improved clinical significance. Aims And Objectives: To determine the spectrum of thyroid disorders in north India and to determine the accuracy and reliability of FNAC in our center. Material And Method: A retrospective study of FNAC thyroid nodules was carried out on 133 patients referred to our Department from July 2021 to August 2020. Slides were retrieved from the cytopathology section of the Department of Pathology, GMCH, reviewed and then classified as per the Bethesda system for reporting thyroid cytopathology. Patients of all ages and gender were included in the study. Results: Total 133 FNAC procedures were performed during the study period. 86 cases were females and 47 were males with male to female ratio of 1:1.83. The nodules of 9 patients were classified as Bethesda category-I, 74 patients as Bethesda category-II, 11 patients as Bethesda category-III, 8 patients as Bethesda category-IV, 9 patients as Bethesda category-V and 22 patients as Bethesda category VI. Out of 133 patients, only 36 patients underwent for surgery among these 36 cases, 4 were classified as Bethesda category-IV , 9 as Bethesda category-V and 22 as Bethesda category-VI on cytology which were further confirmed as cases of thyroid malignancy on histopathology reports. Conclusion: Our study substantiates greater reproducibility among Pathologists using TBSRTC to arrive at a precise diagnosis with an added advantage of predicting the risk of malignancy which enables the clinician to plan for surgery, extent of surgery or follow-up of the patients by repeating the FNA of thyroid nodules at specific intervals.
BASAL CELL CARCINOMA OF HEAD AND NECK REGION: AN ANALYSIS OF 120 CASES
Authors:   Senior Resident Department Of Surgery Gmc Jammu., Kumar Anil , Ahmed Chowdhary Shahnawaz ,   Senior Resident Department Of Surgery Gmc Jammu., Hafeez Wani Adil ,   Professor Plastic Surgery Skims Srinagar., Rasheed Zargar Haroon ,   Additional Professor Plastic Surgery Skims Srinagar.
Published: February 2023

Background: Skin cancer is the most common malignancy and makes upto about one third of all cancers diagnosed. The common skin cancers include nonmelanoma skin cancers and melanoma. The majority of skin cancers of the head and neck are nonmelanoma skin cancers[1]. Out of which BCC is the most common. Basal cell carcinoma accounts for approximately 75% of all cases of nonmelanoma skin cancers. Older age and male sex are associated with higher risk of developing basal cell carcinoma. Basal cell cancer occurs mostly on face , head, scalp, neck and hands. Aims And Objectives: To analyze the presentations of basal cell carcinoma, different areas involved and treatment modalities. Material And Method: Retrospective study from January 2008 to May 2013. Prospective study from June 2013 to June 2015. A total of 120 cases were examined. All retrospective record was retrieved from pathology and plastic surgery department and along with new cases were analysed. Results: A total of 120 cases of BCC were examined out of which 76( 64%) were male and44 (36%) were female. Giving male to female ratio of 1.7:1. Cheek (29%) is the most common site involved. Mean age at presentation was 58.7 years and median age was 60 years with a range of 60 years from 25-85 years. Nodular lesion was seen in 46.07 % cases followed by pigmented 18% and superficial lesion in 15% cases. Conclusion: Basal cell carcinoma is the most common skin cancer of the head and neck region affecting mainly elderly males. Increased incidence is most likely due to the increased ultraviolet radiations, increased outdoor activities, changes in clothing style and ozone depletion. Surgery is the main stay of treatment. Adjuvant treatment is given mostly to stage 3 and stage 4 disease patients and in some patients with positive resection margins.
THE EFFECT OF COMPETENCY, COMMITMENT ANDCOMPENSATION ON TEACHER PERFORMANCE
Authors:   Postgraduate Program-Satya Negara University Indonesia., Sri Rahayu Yani , Siregar Edi ,   Postgraduate Program-Satya Negara University Indonesia., Ilyas Meifida ,   Postgraduate Program-Satya Negara University Indonesia.
Published: February 2023

The purpose of this study was to determine the effect of competence, commitment and the compensation system simultaneously and partially on the performance of teachers at YayasanPendidikanMutiaraBaru, Bekasi City. This study involved 76 respondents who had been determined using census sampling. The analysis technique used in this study is multiple linear regressions. The results of the study show that competency, commitment and compensation simultaneously and partially have a significant impact on teacher performance. The coefficient with an adjusted R square of 0.570 explains that 57.0% of teacher performance is influenced by competence, commitment and the compensation system and 43.0% is influenced by other variabels not investigated in this study.
SOCIAL WORK SANCTIONS: THE IDEA OF REFORMING THE CRIMINAL LAW FOR ERADICATION OF CORRUPTION IN INDONESIA
Authors:   Faculty of Law. Lampung University, Bandar Lampung. Indonesia., Mubaroq Husni , Rosidah Nikmah ,   Faculty of Law. Lampung University, Bandar Lampung. Indonesia., Rifai Eddy ,   Faculty of Law. Lampung University, Bandar Lampung. Indonesia.
Published: February 2023

This article examines social work sanctions as the primary punishment for perpetrators of corruption. Various policies on eradicating corruption in Indonesia have yet to create a deterrent effect or prevent acts of corruption. Corruption in Indonesia is systemic and endemic, so it is detrimental to state finances and violates peoples social and economic rights. This study uses a normative juridical method with a conceptual approach and a statutory approach. The conceptual process is carried out through a literature study, while the statutory procedure is carried out by analyzing the rules related to eradicating corruption in Indonesia. Applying such severe sanctions does not guarantee a deterrent effect for corruptors. Instead, corrupt convicts receive preferential treatment when serving prison sentences in prison. Social work sanctions are constructed as the primary punishment for corruption perpetrators, which are imposed cumulatively and are applied together with other main penalties such as imprisonment and fines. Concretely, social work sanctions as the primary punishment are that the convict is given a social work project according to his expertise. In carrying out social work, the convict must use unique attributes. The convict will voluntarily carry out social work sanctions by the time determined based on a court decision. If the convict is negligent in carrying out the social work sanctions, he will be given an extension of time, but if the target has not been reached, the convict must replace it with a fine by the number of state losses. The implementation of social work sanctions is supervised by investigators, prosecutors, supervisory judges, and correctional institutions.
Estimating Efficiency of Business Ecosystem Functioning in Digital Economy
Authors: Kalenov O. E.
Published: February 2023

The ecosystem business-model is a rather new phenomenon, thus unified methodology of estimating its efficiency has not been formed yet. The majority of researchers focus on the fact that there is a bank in the ecosystem foundation. The article proposes to study ecosystems without binding to any concrete type of activity, for instance, banking, telecommunication, etc. The author highlights a number of aspects that should be necessarily taken into account in resolving this problem. To estimate the efficiency of ecosystem business methodology is put forward based on integral indicator, which includes the following groups of criteria in key lines: operation-synergetic, finance-investment, digital and regulatory. In each of the 4 groups the author identifies factors for estimation and underlines that they can be corrected depending on specific functioning of concrete business-ecosystem. The provided methodology can be used by management of organizations dealing with business-ecosystem building, investors, heads of ministries and departments supervising these directions in order to analyze and take steps aimed at raising the efficiency of the work.
Inhibiting Effect of Cationic Procyanidin Nanoparticles on Drug-Resistant Oral Squamous Cell Carcinoma Cell Lines
Authors: Yuan Xuewei , Li Kunshan , Lv Feifei , Li Na , Zhang Liru , Zhao Shuangling , Duan Yanhao , Qiu Yongle
Published: February 2023

Background:

Multidrug resistance (MDR) is one of the primary causes of tumor chemotherapy
failure. Therefore, it is essential to uncover new drug treatment protocols. In the current study, employing
chitosan (CS) and sodium tripolyphosphate (TPP) as carriers and cross-linking agents, the proanthocyanidins
(PHL)/poly (lactic-co-glycolic acid) (PLGA) were encapsulated by emulsion solvent evaporation,
through which the cationic CS-PLGA-PHL nanosystem was obtained. The effectiveness of CS-PLGAPHL
on the invasion and migration of human oral squamous cell carcinoma cells was discussed, as were
their potential mechanisms.

Materials and Methods:

A CS-PLGA-PHL nanosystem was constructed by emulsion-solvent evaporation.
The size distribution, dispersion, and morphology were characterised by the laser particle size analyser
and transmission electron microscope. Human oral squamous cell carcinoma drug-resistant cell lines
SCC131/R and SCC-15/DDP were cultured in vitro. The two cell types were induced at different concentrations
by CS-PLGA-PHL, after which a CCK⁃8 experiment was performed to determine the effect of
CS-PLGA-PHL on the proliferation of the two cell lines. The 50% inhibitory concentration (IC50) of CSPLGA-
PHL was calculated at different time points. The transwell chamber experiment was performed to
identify the effects of CS-PLGA-PHL on the migration and invasion of OSCC cells. The expression levels
of MMP-2 and MMP-9 were detected by Western blot and q-PCR.

Results:

CS-PLGA-PHL is well dispersed. The PDI appeared to be lowest when the mass ratio of chitosan
to PLGA equaled 1:15. CS-PLGA-PHL exhibited a marked effect in inhibiting the proliferation of SCC-
131/R and SCC-15/DDP as well as the invasion and migration. CS-PLGA-PHL was able to downregulate
the expression of MMP-2 and MMP-9 genes and proteins significantly in drug-resistant cell lines.

Conclusion:

CS-PLGA-PHL for oral squamous cell carcinoma has been successfully prepared to exert
significant inhibition on the proliferation, invasion, and migration of OSCC cells. The mechanism involved
was possibly related to the down-regulation of MMP-2 and MMP-9 expression by CS-PLGA-PHL.
Is Magnetic Resonance Imaging (MRI) Still a Gold Standard to Detect
Breast Cancer: A Meta-analysis
Authors: Su Xiaochen , Wang Shaokai
Published: February 2023

Purpose:

Breast cancer is fatal if it is not diagnosed and treated promptly; consequently,
early and precise diagnosis is essential. In comparison to mammography and sonography, the sensitivity
of MRI to cellular changes and its ability to differentiate benign from malignant tumors make it the
preferred imaging technique. Consequently, the present meta-analysis assessed the effectiveness of
different imaging modalities for breast cancer detection and evaluated the diagnostic accuracy of MRI.

Methods:

Pertinent articles were searched in PubMed, MEDLINE, and Central databases using the
appropriate keywords as per the PRISMA guidelines. Retrospective and prospective studies were included
according to the predefined PICOS criteria. A meta-analysis was performed using RevMan and
MedCalc software, and statistical parameters, such as odds ratio, sensitivity, specificity, likelihood
ratios, and accuracy, were calculated. Publication bias was evaluated using Egger’s and Begg’s tests,
and diagnostic performance was assessed using Youden’s and Bland-Altman's plots.

Results:

Fourteen clinical trials with 4666 breast cancer patients with perineural spread were included.
The included studies used MRI for the detection of breast cancer lesions according to the BI-RADS®
(Breast Imaging Reporting and Data System) guidelines and stated that it has high sensitivity and diagnostic
accuracy. Similarly, the present meta-analysis found a high sensitivity of 86.12 % and a high
diagnostic accuracy of 91.2%. Other than this, we obtained a specificity of 65%, a positive likelihood
ratio of 2.7, and a negative likelihood ratio of 0.22. The pooled odds ratio (OR) was reported to be 1.87
(95% CI 1.42-2.46), and the pooled risk ratio value was 1.19 (95% CI 1.11-1.28).

Conclusion:

Present meta-analysis strongly recommends MRI as an effective imaging method for the
detection of breast cancer.
YBX1, Targeted By Microrna-382-5p, Promotes Laryngeal Squamous Cell
Carcinoma Progression via Modulating RAS/MAPK Signaling
Authors: Zeng Wen , Pan Yiyun , Chen Hailong , Lei Xianhua , Zhang Xiangmin
Published: February 2023

Background:

Laryngeal squamous cell carcinoma (LSCC) is the most common cancer
of head and neck cancer. Y-box binding protein-1 (YBX1) has tumor-promoting effects in some
types of cancers. However, its role in LSCC remains unknown. This study set out to identify the
role of YBX1 in LSCC.

Methods:

Bioinformatics analysis of the Gene Expression Omnibus (GEO) database and our cohort
data were used to explore the association of YBX1 expression with clinicopathological factors
in LSCC. Then, cells with stably or transiently transfected with plasmid or siRNA were constructed
to assess the effect of loss and gain of YBX1 on the biological phenotypes of LSCC cells
in vitro. In addition, subcutaneous xenograft and orthotopic liver tumor mouse models were constructed
for validation. The interrogated miRNA databases and subsequent luciferase reporter assays
were used to confirm the miR-382-5p target of YBX1. At last, KEGG enrichment annotation
from TGCA data was used for downstream analyses of miR-382-5p/YBX1 and verified by PCR
and Western immunoblotting.

Results:

The results showed that significant upregulation of YBX1 in LSCC tumors was correlated
with advanced TNM stage and poor prognosis. Knockdown of YBX1 markedly impaired the
proliferative, invasive, and migratory activity of Tu212 cells. We confirmed that miR-382-5p targets
YBX1 to mediate LSCC progression both in vitro and in vivo. We further confirmed that
miR-382-5p/YBX1 modulated the Ras/MAPK signaling axis to regulate the progression of LSCC.

Conclusion:

Together, our results indicated that YBX1 is an important promoter of LSCC progression.
And miR-382-5p/YBX1/RAS/MAPK signaling pathway can be perceived as a promising
target in the treatment of LSCC.
Exploring the CXCR4/CXCR7/CXCL12 Axis in Primary Desmoid Tumors
Authors: Baccalini Edoardo Andrea , Renne Salvatore Lorenzo , Colombo Piergiuseppe , Pasqualini Fabio , Quagliuolo Vittorio Lorenzo , Cananzi Ferdinando Carlo Maria , Grizzi Fabio , Borroni Elena Monica
Published: February 2023

Background:

Desmoid tumors have an extremely variable natural history. The uncertainty behind desmoid
behavior reflects the complexity, which subtends its development and non-linear advancement. Apart from Wnt-
βcatenin mutation, estrogen receptors, and COX-2 overexpression, little is known about the ability of desmoids to grow
and recur while being unable to metastasize. Several tumors have been shown to express the CXCR4/CXCR7/CXCL12
axis, whose functions are essential for tumoral development.

Aims:

This study aimed to investigate the expression of the CXCR4/CXCR7/CXCL12 axis in primary desmoid tumors
and discuss the potential role of this key-signaling as an antiangiogenic therapeutic strategy.

Method:

In this study, 3 μm-thick consecutive sections from each formalin-fixed and paraffin-embedded tissue block
were treated with mouse monoclonal antibodies developed against CD34, CXCR4, CXCR7, and CXCL12.

Results:

Two distinct vessel populations: CXCR4+ and CXCR4- vessels, have been found. Similarly, chemokine receptor
CXCR7 expression in the entire desmoid tumor series positively stained a portion of tumor-associated vessels,
identifying two distinct subpopulations of vessels: CXCR7+ and CXCR7- vessels. All 8 neoplastic tissue samples expressed
CXCL12. Immunohistochemical positivity was identified in both stromal and endothelial vascular cells. Compared
to CXCR4 and CXCR7, the vast majority of tumor-associated vessels were found to express this chemokine.

Conclusion:

It is the first time, as per our knowledge, that CXCR4/CXCR7/CXCL12 axis expression has been identified
in a desmoid type-fibromatosis series. CXCL12 expression by neoplastic cells, together with CXCR4 and CXCR7
expression by a subgroup of tumor-associated vessels, was detected in all desmoid tumor tissue samples examined.
Since chemokines are known contributors to neovascularization, CXCR4/CXCR7/CXCL12 axis may play a role in
angiogenesis in this soft-tissue tumor histotype, thereby supporting its growth.
WITHDRAWN: Research on an Online Energy Acquisition Method of Transmission Line Based on Impedance Matching
Authors: Wenjun Bao , Min Ge , Zhikun Yuan , Xu He
Published: February 2023

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.
Learning media development based on 3D (3D) animation videos in courses mechanics technique
Authors: Rasiwan Rasiwan , Sasongko Hartanto Wahyu , Arif Robby Mauludy , Setiawan Randy , Rabihati Etty , Supardi Iwan
Published: February 2023

This study aims to: (1) produce 3-dimensional (3-D) animated video-based learning media in the Engineering Mechanics course. (2) Knowing the feasibility level of 3-dimensional (3-D) animated video-based learning media in the Engineering Mechanics course. This research employed to research and development methods to develop learning media based on 3-dimensional (3-D) animation videos. The learning media development procedure is carried out through (1) the preliminary study stage, which consists of a literature review and a field study; and (2) the development stage, which is carried out by making a draft of a model design that is divided into three parts, including: compiling materials, making scripts, preparing 3-dimensional (3-D) animation videos, and editing animation videos. Furthermore, validation of assessments by material experts, media experts, and learning experts, as well as limited trials to assess the feasibility of the learning media created; (3) The evaluation stage is the final stage of the development process related to the final model of 3-dimensional (3-D) animated video-based learning media in the Engineering Mechanics course.
Carta al editor
Authors: Gordillo Alarcón Alicia Salomé
Published: February 2023

Dentro de las funciones académicas resulta indispensable el trabajo de investigación realizada por parte de todos los actores de este escenario, sin embargo, una investigación sin [...]
MEDICATION ADMINISTRATION DISTRACTION OBSERVATION SHEET CHECKLIST: CULTURAL ADAPTATION AND VALIDATION INTO SPANISH
Authors: Gaitan Gómez Olga Lucia , Bueno-Robles Luz Stella , Pape Theresa
Published: February 2023

Introduction. Distractions are sensory inputs that exceed the individual's attention threshold, which is why they have been associated with procedural failures and clinical errors in care practice. Objective. To adapt and validate the “Observation Sheet for Distractions in the Administration of Medication” to the Colombian context. Materials and methods. The study followed a quantitative, cross-sectional, and methodological approach that included the cultural adaptation and validation of both the appearance and the content of an instrument measuring two attributes of the concept of distractions—namely, origin and frequency—with the input of five experts on the topic. Inter-observer reliability was determined through the kappa coefficient, and internal consistency with Cronbach's alpha coefficient in the statistical package SPSS v22. Results. Once adapted and validated to Colombian Spanish, the checklist kept all of the original items of the instrument, with a content validity ratio and index of 1, an inter-observer reliability between 0.82 and 1.00 (substantial agreement), and a Cronbach's alpha of 0.54 (acceptable). Conclusions. Few studies admit to using the instrument as the author proposes; some draw inspiration from it to create their own instruments, while others use it but do not report its validation. Only three studies, including this one, report psychometric analyses performed on the instrument with minor changes after its execution. The instrument can be applied to clinical nursing practice in Colombia; in the future, it is recommended to include new attributes of the concept.
Design of Hexacopter Tethered Drone
Authors: Karthik S. , Basha N Nawaz , Ajith V.
Published: February 2023

Abstract: This paper proposed the development of an tethered Drone to be used for application. Drones become essential for various application. The main drawback of the drones is that the time of flight is very less (around 20 minutes).The proposed system aims to provide continuous power supply to the drone by using power supply from ground. The twisting and tangling of wires is another problem, so we have provided a slip ring mechanism to avoid twisting of cable. In this system author used IMU 6DOF (3-axis accelerometer& 3-axis gyroscope) which ensure it smooth movement, graceful motion and trajectory tracing. GPS system and barometric sensor makes it more efficient in autonomous mode. UAVs have limited operational autonomy, determined by their on-board available power. An autonomous power tethered UAV-UGV team couples those two classes through a power linkage. This serves to increase the UAV’s autonomy in terms of flight time, while concurrently the aerial platform’s utility as an eye-in-the-sky can provide the UGV with increased knowledge of its surroundings. Finally, this physical constraint can grant additional benefits at aerial vehicle control level, especially under the potential presence of strong wind gusts. The developed autonomous operation strategy is examined within a simulated scenario with limited prior map knowledge, which includes a number of unmapped challenges.
Design and Fabrication of Automatic Side Stand for Two Wheelers
Authors: Nagasankar Dr. P. , Kumar S. Aadhish , Sriram B. , Kumar S. Varun
Published: February 2023

Abstract: Existing bikes have a system of beeping sounds when the side stand is in the vertical position. But this project's purpose is to make side-stand automatic and aesthetically pleasing to look at. So, it is designed as an automatic side stand for motorcycles. The project we develop the motorcycle side stand, slide automatically. For this purpose, automation uses the motorcycle ignition system to complete the electronic circuit such that when a person starts the ignition system using the ignition key, the side stand will immediately be in a horizontal position. The whole system works on an electronic circuit in the motorbike with the help of electronic components such as servomotor and Adriano. We used the microcontroller is an Adriano circuit and the motor is a servomotor for automation purposes using the Adriano programming. Whenever you turn on the key, the signal of position angle goes to the Adriano board. From the Arduino, a signal in the form of voltage comes to the servomotor. Finally, the side stand rotates at an angle which is programmed in software for the servomotor.
FORMAÇÃO DOCENTE E DESENVOLVIMENTO PROFISSIONAL: UMA ANÁLISE A PARTIR DO QUE OS PROFESSORES PENSAM ACERCA DO SEU PERCURSO FORMATIVO EM TRABALHO
Authors: Barbosa Luciane Maria Molina , Santos Juçara Maria Lemes Giffoni Avila , Santos Roberta Karen dos , Guedes Denyse Moreira , Adami Fabíola Andrea Chofard
Published: February 2023

The Teaching work implies the union of knowledge, interactions and experiences achieved in different phases of teachers' lives. This article aims to know the factors that contributed to the professional development of three teachers of basic education, in the periods of teaching in early childhood education, in the initial years of elementary education and in special education, at a time when teaching is established as the main element of professional commitment. For this purpose, the semi-structured interview was used as a data collection instrument, making it possible to know what they think about the skills that are positive for the improvement of the career, with reflexes also for the students' learning. We conclude that the professional development is supported in the belonging of these teachers to the different spaces of formation, no matter how long they have been teaching. In the interviews it was evident that the continuous training contributes to the modification of the professionalism of the teacher and develops domains necessary for its qualification, also acting in the possible solutions to the real problems found in the school and especially in the teaching.
Osteonecrosis of the Femoral Head
Authors: Sohatee Mark Andrew , Malviya Ajay
Published: February 2023

Avascular necrosis when occurring as osteonecrosis of the femoral head poses a challenge for hip surgeons due to the risk of collapse of the articular cartilage. The pathological process and its various stages have been classified using a number of systems to aid with diagnostic decision making and employing a variety of methods of operative intervention for appropriate indications. When there is such a plethora of manage-ment options, it highlights that there is no one “excellent” option for management of the condition. Having undertaken a scoping review, the authors conclude that surgical decision-making, based on the options available, should be tailored to patient factors (aetiology, age, collapse, etc.) and surgical skills set (microvascular surgery, pedicle grafting versus non-vascularised versus synthetic grafting). There are different hip preservation techniques in the literature with different success rates, however, from the current data available, it can be observed that vascularised techniques result in a lesser rate of conversion to arthroplasty but require greater time and technical abilities in microsurgery than non-vascularised techniques.
Psychological Well-Being: An Empirical Study of Indian Industry on Work-Life Integration During Covid 19
Authors: Pujitha J. , Shamshuddin Dr. Shaik , Deepa Mohan Dr. N.
Published: February 2023

Minimizing the effects of COVID-19 is one of the world's highest priorities, and India is taking essential measures to curb the outbreak. Many businesses promoted social distancing through the announcement of compulsory work-from-home. In this backdrop, Remote Work has become a significant model mainly to retain talent and attrition. The present study analyses whether work-life integration and work-life satisfaction are related to psychological well-being. Research hypotheses are formulated based on the investigation of the literature review. This data was collected in India during July and October 2020 while the Covid pandemic was coming down to normal. The survey was aimed at people who work in Indian-based companies. Workers received an electronic version of the questionnaire, and organizations received e-mail requests. The decision was made to use the comfort sampling method. During the pandemic, a sample of 400 employees from the Information Technology industry in the cities of Hyderabad and Bangalore, India. Work-Life integration leading to Psychological Well-being were analyzed considering the role of work-life satisfaction as a mediator. This research focuses on job and life satisfaction, showing the mechanisms that help workers in remote working conditions stay mentally healthy during a pandemic. This mediation study revealed that Work-life satisfaction has an optimistic and robust relationship with psychological health, with this relationship being influenced by work satisfaction and life satisfaction among the Indian IT companies surveyed. These studies' findings suggest that a successful workfrom- home community is built on a foundation of work-life integration based on contentment. The research findings are that positive work-life integration contributes to employees' positive levels of psychological well-being. We found that the higher the job and life satisfaction, the better the psychological well-being. Since the current study is a cross-sectional analysis, there are some restrictions on how long the investigation can last. Longitudinal research should be conducted to improve the results of the studies.
TRANSIÇÃO AGROECOLÓGICA NO TERRITÓRIO DO BOLSÃO, TRÊS LAGOAS - MATO GROSSO DO SUL, BRASIL
Authors: Almeida Rosemeire Aparecida de , Dubos-Raoul Marine
Published: February 2023

Os impactos socioambientais no campo, que estão na raiz da crise agroalimentar em escala planetária, foram gerados no Brasil a partir do modelo de desenvolvimento rural conhecido como Revolução Verde. A partir de 1960, este paradigma agrícola buscou modernizar o latifúndio via mudança técnica sem alterar a estrutura fundiária. Tornou-se crescente as consequências contraproducentes deste arquétipo de agricultura, tais como: concentração fundiária, erosão do solo, desertificação, poluição por agrotóxicos e perda de biodiversidade. Como contraponto, emerge mundialmente o tema “campesinato e agroecologia” como alternativa ao modelo convencional de agricultura, e se inicia no Brasil a construção deste novo paradigma produtivo. Apesar da hegemonia no Território Rural do Bolsão da propriedade capitalista da terra voltada à pecuária e à silvicultura, tem-se, contraditoriamente, a presença da pequena propriedade familiar camponesa voltada ao autoconsumo e a produção/comercialização de excedentes. A criação do Núcleo de Agroecologia do Bolsão-UFMS (NEA-BOLSÃO) é fruto desta realidade e representa a articulação que se iniciou, em 2013, entre o Laboratório de Geografia Agrária, da UFMS/Campus de Três Lagoas, o Instituto de Sociología e Estudios Campesinos (ISEC), Universidade de Córdoba-Espanha, e um grupo de famílias em transição agroecológica do assentamento de reforma agrária 20 de Março, em Três Lagoas. Este artigo visa resgatar esta experiência ainda em curso de transição agroecológica no PA 20 de Março, promovida pelo NEA-Bolsão, analisando as seguintes ações implantadas nas unidades de referência agroecológica: canais curtos de comercialização, feiras de resgate das espécies crioulas, cursos e oficinas sobre caldas e biofertilizantes e o estímulo ao associativismo.
Information is a key: Systematic literature review and empirical results on role configurations of chief information officers and chief digital officers
Authors: Ulrich Patrick , Lehmann Sonja
Published: February 2023

In the context of the digitization of companies, the executive positions of chief information officer (CIO) and chief digital officer (CDO) are becoming more important. Based on a systematic literature analysis and an empirical survey among German companies, this article shows that there are clear overlaps and role conflicts between CIOs (Hunter, 2010) and CDOs (Kunisch et al., 2020) in company practice. However, the CDO in particular has some areas of responsibility, such as communicating the need for digitization in companies, which are not attributed to the CIO. These might therefore be seen as new tasks. In contrast, topics such as information technology (IT) costs and efficiency as well as strategy orientation, but also cybersecurity and IT governance are more likely to be seen as the responsibility of the CIO. Judging by the results of the literature analysis and the empirical study, it might be feasible to maintain both positions in the future.
Conduction System Pacing: How far are we from the “electrical” bypass?
Authors: Sdogkos Evangelos , Iliodromitis Konstantinos , Xanthopoulos Andrew , Triposkiadis Filippos , Skoularigis John , Bogossian Harilaos , Vogiatzis Ioannis
Published: February 2023

Conduction system pacing is an alternative practice to conventional
right ventricular apical pacing. It is a method that maintains
physiologic ventricular activation, based on a correct
pathophysiological basis, in which the pacing lead bypasses the lesion
of the electrical fibers, and the electrical impulse transmits through
the intact adjacent conduction system. For this reason, it might
reasonably characterized by the term “electrical bypass” compared to
the coronary artery bypass in revascularization therapy. In this review
reference is made to the sequence of events that conventional right
ventricular pacing may cause adverse outcomes. Furthermore, there is a
reference to alternative strategies and pacing sites. Interest focuses
on the modalities for which there is data from the literature, namely
for the Right Ventricular (RV) septal pacing, the His Bunde pacing
(HBP), and the Left Bundle Branch pacing (LBBP). A more extensive
reference is about the HBP, for which there are the most updating data.
We analyze the considerations that limit HBP wide application in three
axes, and we also present the data for the implantation and follow-up of
these patients. Then, the indications with their most important studies
to date are described in detail, not only in their undoubtedly positive
findings but also in their weak aspects, because of which, this pacing
mode has not yet received a strong recommendation for implementation.
Finally, there is a report on LBBP, focusing mainly on its points of
differentiation from HBP.