bluuebunny/crossref_metadata_2025 huggingface dataset:
City Logistics as an Imperative Smart City Mechanism: Scrutiny of Clustered EU27 Capitals
Authors: Škultéty Filip , Beňová Dominika , Gnap Jozef
Published: March 2021

In large urban agglomerations, various logistical problems arise due to high population density and deficient transport infrastructure. City logistics involves the efficient distribution of freight transport in urban areas and approaches to mitigate environmental impacts and traffic congestion. This paper aims to use a two-step cluster analytic approach to segmentation of EU27 capital cities based on their city logistics performance. To obtain primary outcomes, the log-likelihood measure in SPSS Statistics was used. The results can be used to identify the development and implementation of logistics measures in capitals across the EU. In addition to clustering, the statistical analysis evaluates the position of investigated cities concerning traffic congestions, and from an environmental point of view, the carbon dioxide produced from transport. The scrutiny delivers practical outlooks on how clustering can be undertaken and proves how the clusters can be used to plan city logistics and supply chain management. Finally, the paper deals with smart city indices from the perspective of sustainable mobility and examines its correlation with city logistics.
Strategies of Two-Level Green Technology Investments for Coal Supply Chain under Different Dominant Modes
Authors: Da Bowen , Liu Chuanzhe , Liu Nana , Fan Sidun
Published: March 2021

We consider a coal supply chain with a coal enterprise and a manufacturer, where the coal enterprise invests in clean coal technology, and the manufacturer invests in carbon reduction technology. The government offers subsidies for the investments of clean coal technology and carbon reduction technology. We examine optimal clean coal technology inputs in a coal enterprise and carbon reduction quantity in a manufacturer under the modes of coal-enterprise-led and manufacturer-led, respectively, using a Stackelberg game theory model. We obtain some interesting results. First, carbon reduction by the manufacturer is restrained when clean coal technology cost and carbon reduction cost are increased, regardless of the dominant modes, and clean coal technology input decreases when clean coal technology cost increases; however, a high carbon reduction cost has no effect on clean coal technology input when the manufacturer leads. Second, the clean coal technology subsidy for coal enterprises promotes clean coal technology inputs and carbon reductions, and the carbon reduction subsidy encourages carbon reduction without supporting clean coal technology input. Last, carbon reduction performance is better achieved under the manufacturer-led model than the coal-enterprise-led model. However, it should be noticed that the capital resource only relies on government subsidy in this article. In the future, this study could be used for green supply chain investment, and could be helpful for sustainability development.
Blue Economy and Coastal Tourism: A Comprehensive Visualization Bibliometric Analysis
Authors: Kabil Moaaz , Priatmoko Setiawan , Magda Róbert , Dávid Lóránt Dénes
Published: March 2021

This paper aims to analyze the scientific production of the blue economy and coastal tourism research fields to identify research topics and publication patterns. Accordingly, bibliometric analysis was selected as a quantitative meta-analysis literature review method. Scopus was the main database for extracting the scientific production in blue economy and coastal tourism. Various bibliometrics analysis techniques were used to analyze 476 and 49 publications in blue economy and coastal tourism, respectively. The main results are summarized as follows: (i) the number of publications in the blue economy scientific sector has increased significantly, and (ii) contrarily, a relatively small body of blue economy literature is concerned with the coastal tourism sector despite its significant role in the blue economy.
Connectedness to Nature and Pro-Environmental Behaviour from Early Adolescence to Adulthood: A Comparison of Urban and Rural Canada
Authors: Anderson Daniel J. , Krettenauer Tobias
Published: March 2021

Previous research has demonstrated that emotional connectedness to nature is among the strongest predictors of pro-environmental behaviour. This study investigated the influence of age, gender and living context on emotional connectedness to nature and pro-environmental behaviour in a Canadian sample. Study participants completed an environmental survey, which assessed demographic data as well as levels of emotional connectedness to nature and pro-environmental behaviour. The study contained 1251 participants equally divided across gender, sampled from four different age groups in rural versus urban living contexts throughout Canada. Study results revealed that emotional connectedness to nature was the strongest predictor of pro-environmental behaviour in comparison to the other factors. It was found that adults displayed significantly higher levels of emotional connectedness to nature and pro-environmental behaviour in comparison to adolescents, and that females displayed higher levels of both emotional connectedness to nature and pro-environmental behaviour in comparison to males. Moreover, urban and rural participants significantly differed in their levels of pro-environmental behaviour, but not in their levels of emotional connectedness to nature.
Short-Term Solar Power Forecasting: A Combined Long Short-Term Memory and Gaussian Process Regression Method
Authors: Wang Ying , Feng Bo , Hua Qing-Song , Sun Li
Published: March 2021

Solar power is considered a promising power generation candidate in dealing with climate change. Because of the strong randomness, volatility, and intermittence, its safe integration into the smart grid requires accurate short-term forecasting with the required accuracy. The use of solar power should meet requirements proscribed by environmental law and safety standards applied for consumer protection. First, time-series-based solar power forecasting (SPF) model is developed with the time element and predicted weather information from the local meteorological station. Considering the data correlation, long short-term memory (LSTM) algorithm is utilized for short-term SPF. However, the point prediction provided by LSTM fails in revealing the underlying uncertainty range of the solar power output, which is generally needed in some stochastic optimization frameworks. A novel hybrid strategy combining LSTM and Gaussian process regression (GPR), namely LSTM-GPR, is proposed to obtain a highly accurate point prediction with a reliable interval estimation. The hybrid model is evaluated in comparison with other algorithms in terms of two aspects: Point prediction accuracy and interval forecasting reliability. Numerical investigations confirm the superiority of LSTM algorithm over the conventional neural networks. Furthermore, the performance of the proposed hybrid model is demonstrated to be slightly better than the individual LSTM model and significantly superior to the individual GPR model in both point prediction and interval forecasting, indicating a promising prospect for future SPF applications.
Assessing the Prospects of Transboundary Multihazard Dynamics: The Case of Bhotekoshi–Sunkoshi Watershed in Sino–Nepal Border Region
Authors: Lamichhane Suraj , Aryal Komal Raj , Talchabhadel Rocky , Thapa Bhesh Raj , Adhikari Rabindra , Khanal Anoj , Pandey Vishnu Prasad , Gautam Dipendra
Published: March 2021

The impacts of multihazards have become more pronounced over the past few decades globally. Multiple hazards and their cascading impacts claim enormous losses of lives, livelihoods, and built environment. This paradigm prompts integrated and multidisciplinary perspectives to identify, characterize, and assess the occurrence of multihazards and subsequently design countermeasures considering impending multihazard scenarios at the local level. To this end, we considered one of the most egregious transboundary watersheds, which is regarded as a multihazard hotspot of Nepal, to analyze the underlying causes and cascade scenarios of multihazards, and their associated impacts. In this paper, geophysical, hydrometeorological, and socioeconomic perspectives are formulated to characterize the watershed from the dimension of susceptibility to multihazard occurrence. To characterize the complex dynamics of transboundary multihazard occurrence, insights have been presented from both the Nepali and the Chinese sides. Individual case studies and the interrelation matrix between various natural hazards are also presented so as to depict multihazard consequences in the transboundary region. The sum of the observations highlights that the watershed is highly vulnerable to a single as well as multiple natural hazards that often switch to disasters.
When Is Choice Empowering? Examining Gender Differences in Varietal Adoption through Case Studies from Sub-Saharan Africa
Authors: Polar Vivian , Ashby Jaqueline A. , Thiele Graham , Tufan Hale
Published: March 2021

This paper examines the question of what makes choice empowering and critiques prevalent approaches to empowerment focused narrowly on agency as the ability of individuals to make their own free choices and act independently. The implications of a narrow focus on agency are illustrated with the examples of technology choice in agriculture, specifically choices involved in the adoption of improved plant varieties. This example elucidates the limits of individual agency and permits an analysis of how choices may be structured to be either empowering or disempowering, with examples from specific plant breeding cases. In view of the importance given to equitable choice of technology for closing the gender gap in agricultural productivity and sustainability, the paper explores what practical steps can be taken towards a balanced approach to empowerment. An approach to designing a new plant variety by constructing choice differently is illustrated, using information on gender relations. The paper derives lessons from the plant breeding cases to inform other kinds of interventions, so that work on how choices are defined is given as much importance for empowerment as creating the option to choose. Agents who exercise power over rules and resources can either reproduce the status quo or innovate; thus, a balanced approach to empowerment requires careful analysis of the elements of choice.
New Image Recognition Technique for Intuitive Understanding in Class of the Dynamic Response of High-Rise Buildings
Authors: Porras Soriano Rocío , Mobaraki Behnam , Lozano-Galant José Antonio , Sanchez-Cambronero Santos , Prieto Muñoz Federico , Gutierrez Juan José
Published: March 2021

In the last years, more and more studies have highlighted the advantages of complementing traditional master classes with additional activities that improve students’ learning experience. This combination of teaching techniques is specially advised in the field of structural engineering, where intuition of the structural response it is of vital importance to understand the studied concepts. This paper deals with the introduction of a new (and more encouraging) educational tool to introduce students intuitively to the dynamic response of structures excited with an educational shaking table. Most of the educational structural health monitoring systems use sensors to determine the dynamic response of the structure. The proposed tool is based on a radically different approach, as it is based on low-cost image-recognition techniques. In fact, it only requires the use of an amateur camera, a black background, and a computer. In this study, the effects of both the camera location and the image quality are also evaluated. Finally, to validate the applicability of the proposed methodology, the dynamic response of small-scale buildings with different typologies is analyzed. In addition, a series of surveys were conducted in order to evaluate the activity based on student´s satisfaction and the actual acquisition and strengthening of knowledge.
Using Social Media as a Medium for CSR Communication, to Induce Consumer–Brand Relationship in the Banking Sector of a Developing Economy
Authors: Gupta Shuchi , Nawaz Nishad , Tripathi Abhishek , Muneer Saqib , Ahmad Naveed
Published: March 2021

Social media has emerged as a flexible and interactive communication medium in the present digital era. Contemporary businesses use social media to achieve different communication objectives. However, using social media as a communication medium for corporate social responsibility (CSR) communication with stakeholders like, consumers is not well-explored in the existing literature. Furthermore, prior studies have also failed to consider the blend of CSR communication and social media to achieve consumer-related outcomes, for example, their loyalty and purchase likelihood. To this end, the objective of this study is to examine the relationship of the CSR communication of a bank through social media with consumer loyalty and purchase intention. The current study also proposes brand admiration as a potential mediator between this relationship. The data were collected from the banking consumers through a self-administered questionnaire in a developing economy. The data were analyzed through the structural equation modeling (SEM) technique using AMOS software. The results of the current survey confirmed that CSR communication of a bank on social media has direct and indirect, via brand admiration, relations with consumer loyalty, and purchase intentions. The outcomes of this survey will be helpful for the policymakers to understand the importance of CSR communication on social media to enhance the loyalty, and purchase intention of banking consumers.
Evaluation and Monitoring of Urban Public Greenspace Planning Using Landscape Metrics in Kunming
Authors: Liu Min , Li Xiaoma , Song Ding , Zhai Hui
Published: March 2021

Urban greenspace planning plays a crucial role in improving the quality of human settlements and the living standard of citizens. Urban public greenspace (UPGS) is an important part of urban greenspaces. Existing literature rarely includes a scientific evaluation of greenspace plans (including of UPGS) and plan implementation effects. To bridge this gap, this study evaluated and monitored the UPGS plan enacted in 2010 in Kunming, China. Object-based image classification and visual interpretation of satellite images and Google Earth imagery were used to quantify the different periods of UPGS implementation. Six indicators and monitoring at four classic sites were applied to explore the change at two scales (overall scale and district scale) for monitoring the UPGS plan execution. The results showed that UPGS structure greatly improved after plan implementation. However, UPGS provision per capita has not reached the level of greenspace planning and the connectivity was poor. Significant implementation inequalities existed in each district and implementation has lagged behind schedule. This study contributes to a better understanding of greenspace planning and urban planning in general, which can help improve future planning and planning decisions.
Claims Solutions Using a Blockchain System in International Logistics
Authors: Batarlienė Nijolė , Meleniakas Maksimas
Published: March 2021

A claim can be understood as a negative result of the performance of a contract, as it is necessary to fulfill the obligation and/or indemnify (freight damage claim, for example). Today’s claims management faces a variety of problems, such as inefficient claims postings, possible data forgery, and a very lengthy claims resolution process. All these problems can be solved by using a synthesis of innovative tools, e.g., a blockchain system, game theory, and statistical methods. Theoretical possibilities and practical examples regarding solving claims management problems were identified by analyzing various scientific sources. However, it remained unclear whether these methods could interact with each other, complicate the existing claims settlement process or not, or whether a synthesis of such measures would be viable. Therefore, a qualitative study was conducted and answers to the above questions were found. The research revealed that 75% of international Lithuanian logistics companies can apply the synthesis of these methods in claims management and solutions. Using the concordance coefficient formula, the value of W was calculated. This coefficient indicated that the opinions of the experts who participated in the study were somewhat similar. The value of the actual χ2 distribution was also calculated. The result obtained shows that the experts’ opinions were somewhat harmonized and that their compatibility was not accidental. The use of blockchain system synthesis in combination with game theory and statistical methods could help international logistics companies to reduce their costs, speed up the management process, and increase data security and reliability while ensuring structured one-stop claims management.
Design and Implementation of a Virtual Laboratory for Physics Subjects in Moroccan Universities
Authors: El Kharki Khadija , Berrada Khalid , Burgos Daniel
Published: March 2021

Laboratory experimentation has a vital role in science education. With the potential offered by information and communication technologies for the educational domain, virtual laboratories have emerged as a valuable alternative to face-to-face, hands-on laboratories. Moreover, the possibility of virtual laboratories opens new perspectives for higher education sustainability. They are a perfect approach for training learners to understand scientific principles in many fields of science by offering them the possibility to illustrate the scientific phenomena through automated and virtual practical activities that employ computer simulation. In this work, we present the use of computer simulation combined with the JavaScript programming language for the development of a low-cost virtual laboratory integrated into an interactive learning environment based on the Moodle platform. The methodology was based on the instructional design model ADDIE (Analysis, Design, Development, Implementation, and Evaluation), which structures the development planning of online teaching resources in different stages (analysis, design, development, implementation, and evaluation). The virtual laboratory was developed by Moroccan universities, with the help of European partners, and it was implemented in the 12 science faculties in Morocco. It presents a great choice for supporting laboratory activities for learners in the first year of their bachelor’s degree program. This virtual laboratory includes 12 virtual practical activities mapped to the physics curriculum, and they can be operated via the Internet on computers. The proposed virtual learning environment was evaluated by teachers and learners from the science faculties. The obtained results, together with similar findings from other studies, indicate the positive impact of the use of a virtual laboratory on learning outcomes, and support the adoption of the proposed learning environment in laboratory educational procedures as an alternative to physical laboratories.
Authenticity, Perceived Value and Loyalty in Marine Tourism Destinations: The Case of Zhoushan, Zhejiang Province, China
Authors: Su Yongjun , Xu Junjie , Sotiriadis Marios , Shen Shiwei
Published: March 2021

A very good understanding and knowledge about the tourists’ perceptions are of critical importance for the management and marketing of tourism destinations and sites of all types. The aim of this study was to investigate the perceived authenticity and its relationship with perceived value and loyalty of tourists in the context of marine tourism. First, the study proposed a research model based on the conceptual foundations of authenticity, perceived value and loyalty. The suggested model was then tested by means of a quantitative survey conducted in Zhoushan, one of the most popular Chinese marine tourism destinations. The study’s findings revealed that the object-based authenticity and interpersonal authenticity significantly affected perceived value and loyalty of tourists, and the perceived value partly mediated the relationship between authenticity and loyalty. The article is completed by discussing the theoretical and managerial implications.
Evaluating the Authenticity of Naxi Music in Three Stages from the Perspective of Naxi Musicians: An Application of Lacan’s Mirror Stage Theory
Authors: Li Dawei , Zhou Shangyi
Published: March 2021

How do people evaluate the transformation of a local music scene under tourism? Using Jacques Lacan’s mirror stage theory, Manuel Castells’ identity theory and Erik Cohen’s authentication theory, we build a framework to judge the authenticity of Naxi music in Lijiang, China, based on interviews, literature analysis and performance analysis. The conclusions are as follows. First, there are significant differences in authenticity among the three stages of Naxi music, as defined by Lacan’s theory. Second, we modify Erik Cohen’s authentication concept from the perspective of Lacan and read the spirit of persistence and innovation as “hot” authentication in the postmirror stage. Naxi musicians have clear project identity, as defined by Manuel Castells. Project identity means that they do not follow the mirror image of tourists blindly and pay attention to music and their own development. This research contributes to the sustainable development of intangible cultural heritage in tourism.
Source Identification of Cd and Pb in Typical Farmland Topsoil in the Southwest of China: A Case Study
Authors: Zhang Junji , Shi Zeming , Ni Shijun , Wang Xinyu , Liao Chao , Wei Fei
Published: March 2021

Cd and Pb in farmland topsoil are controlled by many factors. To identify the source of potential toxic metals in the farmland topsoil around Mianyuan River, the chemical analysis and multivariate statistical analysis are performed in this study. The results indicate the following: (1) The concentration of Cd and Pb in soil exceed the background value of Chinese soil elements. (2) Cd is significantly enriched in the whole region and Pb is locally enriched, both of them are more or less influenced by human activities. (3) The contents of Cd and Pb increase significantly following the flow direction of river. (4) Pb isotope analysis indicates that the main source of Pb in the soil include the air dust, coal and phosphate plant, and the contribution of them decreases successively. (5) Linear correlation analysis and principal component analysis show that the main sources of Cd in the soil are mining phosphate rock, air dust, phosphate plant and coal mining.
An Analysis of the Recurrence Coefficients for Symmetric Sobolev-Type Orthogonal Polynomials
Authors: Garza Lino G. , Garza Luis E. , Huertas Edmundo J.
Published: March 2021

In this contribution we obtain some algebraic properties associated with the sequence of polynomials orthogonal with respect to the Sobolev-type inner product:p,qs=∫Rp(x)q(x)dμ(x)+M0p(0)q(0)+M1p′(0)q′(0), where p,q are polynomials, M0, M1 are non-negative real numbers and μ is a symmetric positive measure. These include a five-term recurrence relation, a three-term recurrence relation with rational coefficients, and an explicit expression for its norms. Moreover, we use these results to deduce asymptotic properties for the recurrence coefficients and a nonlinear difference equation that they satisfy, in the particular case when dμ(x)=e−x4dx.
In Vacuo Dispersion-Like Spectral Lags in Gamma-Ray Bursts
Authors: Amelino-Camelia Giovanni , D’Amico Giacomo , Fiore Fabrizio , Puccetti Simonetta , Ronco Michele
Published: March 2021

Some recent studies exposed preliminary but rather intriguing statistical evidence of in vacuo dispersion-like spectral lags for gamma-ray bursts (GRBs), a linear correlation between time of observation and energy of GRB particles, which is expected in some models of quantum geometry. Those results focused on testing in vacuo dispersion for the most energetic GRB particles, and in particular only included photons with energy at emission greater than 40 GeV. We here extend the window of the statistical analysis down to 5 GeV and find results that are consistent with what had been previously noticed at higher energies.
Symmetries for Nonconservative Field Theories on Time Scale
Authors: Postavaru Octavian , Toma Antonela
Published: March 2021

Symmetries and their associated conserved quantities are of great importance in the study of dynamic systems. In this paper, we describe nonconservative field theories on time scales—a model that brings together, in a single theory, discrete and continuous cases. After defining Hamilton’s principle for nonconservative field theories on time scales, we obtain the associated Lagrange equations. Next, based on the Hamilton’s action invariance for nonconservative field theories on time scales under the action of some infinitesimal transformations, we establish symmetric and quasi-symmetric Noether transformations, as well as generalized quasi-symmetric Noether transformations. Once the Noether symmetry selection criteria are defined, the conserved quantities for the nonconservative field theories on time scales are identified. We conclude with two examples to illustrate the applicability of the theory.
Profile of Small RNAs, vDNA Forms and Viral Integrations in Late Chikungunya Virus Infection of Aedes albopictus Mosquitoes
Authors: Marconcini Michele , Pischedda Elisa , Houé Vincent , Palatini Umberto , Lozada-Chávez Nabor , Sogliani Davide , Failloux Anna-Bella , Bonizzoni Mariangela
Published: March 2021

The Asian tiger mosquito Aedes albopictus is contributing to the (re)-emergence of Chikungunya virus (CHIKV). To gain insights into the molecular underpinning of viral persistence, which renders a mosquito a life-long vector, we coupled small RNA and whole genome sequencing approaches on carcasses and ovaries of mosquitoes sampled 14 days post CHIKV infection and investigated the profile of small RNAs and the presence of vDNA fragments. Since Aedes genomes harbor nonretroviral Endogenous Viral Elements (nrEVEs) which confers tolerance to cognate viral infections in ovaries, we also tested whether nrEVEs are formed after CHIKV infection. We show that while small interfering (si)RNAs are evenly distributed along the full viral genome, PIWI-interacting (pi)RNAs mostly arise from a ~1000 bp window, from which a unique vDNA fragment is identified. CHIKV infection does not result in the formation of new nrEVEs, but piRNAs derived from existing nrEVEs correlate with differential expression of an endogenous transcript. These results demonstrate that all three RNAi pathways contribute to the homeostasis during the late stage of CHIKV infection, but in different ways, ranging from directly targeting the viral sequence to regulating the expression of mosquito transcripts and expand the role of nrEVEs beyond immunity against cognate viruses.
Focus on HPV Infection and the Molecular Mechanisms of Oral Carcinogenesis
Authors: Santacroce Luigi , Di Cosola Michele , Bottalico Lucrezia , Topi Skender , Charitos Ioannis Alexandros , Ballini Andrea , Inchingolo Francesco , Cazzolla Angela Pia , Dipalma Gianna
Published: March 2021

This study is focused on the epidemiological characteristics and biomolecular mechanisms that lead to the development of precancerous and cancerous conditions of oral lesions related to Human Papilloma Virus (HPV) infections. Current evidence from the literature demonstrates the role of HPV in potentially malignant oral disorders. Therefore, the underlying biomolecular processes can give arise, or contribute to, benign lesions as well as to oral carcinogenesis.
Effect of Inactivation Methods on SARS-CoV-2 Virion Protein and Structure
Authors: Loveday Emma K. , Hain Kyle S. , Kochetkova Irina , Hedges Jodi F. , Robison Amanda , Snyder Deann T. , Brumfield Susan K. , Young Mark J. , Jutila Mark A. , Chang Connie B. , Taylor Matthew P.
Published: March 2021

The risk posed by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) dictates that live-virus research is conducted in a biosafety level 3 (BSL3) facility. Working with SARS-CoV-2 at lower biosafety levels can expedite research yet requires the virus to be fully inactivated. In this study, we validated and compared two protocols for inactivating SARS-CoV-2: heat treatment and ultraviolet irradiation. The two methods were optimized to render the virus completely incapable of infection while limiting the destructive effects of inactivation. We observed that 15 min of incubation at 65 °C completely inactivates high titer viral stocks. Complete inactivation was also achieved with minimal amounts of UV power (70,000 µJ/cm2), which is 100-fold less power than comparable studies. Once validated, the two methods were then compared for viral RNA quantification, virion purification, and antibody detection assays. We observed that UV irradiation resulted in a 2-log reduction of detectable genomes compared to heat inactivation. Protein yield following virion enrichment was equivalent for all inactivation conditions, but the quality of resulting viral proteins and virions were differentially impacted depending on inactivation method and time. Here, we outline the strengths and weaknesses of each method so that investigators might choose the one which best meets their research goals.
All-Atom MD Simulations of the HBV Capsid Complexed with AT130 Reveal Secondary and Tertiary Structural Changes and Mechanisms of Allostery
Authors: Pérez-Segura Carolina , Goh Boon Chong , Hadden-Perilla Jodi A.
Published: March 2021

The hepatitis B virus (HBV) capsid is an attractive drug target, relevant to combating viral hepatitis as a major public health concern. Among small molecules known to interfere with capsid assembly, the phenylpropenamides, including AT130, represent an important antiviral paradigm based on disrupting the timing of genome packaging. Here, all-atom molecular dynamics simulations of an intact AT130-bound HBV capsid reveal that the compound increases spike flexibility and improves recovery of helical secondary structure in the spike tips. Regions of the capsid-incorporated dimer that undergo correlated motion correspond to established sub-domains that pivot around the central chassis. AT130 alters patterns of correlated motion and other essential dynamics. A new conformational state of the dimer is identified, which can lead to dramatic opening of the intradimer interface and disruption of communication within the spike tip. A novel salt bridge is also discovered, which can mediate contact between the spike tip and fulcrum even in closed conformations, revealing a mechanism of direct communication across these sub-domains. Altogether, results describe a dynamical connection between the intra- and interdimer interfaces and enable mapping of allostery traversing the entire core protein dimer.
Epitope Mapping of the Diphtheria Toxin and Development of an ELISA-Specific Diagnostic Assay
Authors: De-Simone Salvatore Giovanni , Gomes Larissa Rodrigues , Napoleão-Pêgo Paloma , Lechuga Guilherme Curty , de Pina Jorge Soares , da Silva Flavio Rocha
Published: March 2021

Background: The diphtheria toxoid antigen is a major component in pediatric and booster combination vaccines and is known to raise a protective humoral immune response upon vaccination. Although antibodies are considered critical for diphtheria protection, little is known about the antigenic determinants that maintain humoral immunity. Methods: One-hundred and twelve 15 mer peptides covering the entire sequence of diphtheria toxin (DTx) protein were prepared by SPOT synthesis. The immunoreactivity of membrane-bound peptides with sera from mice immunized with a triple DTP vaccine allowed mapping of continuous B-cell epitopes, topological studies, multiantigen peptide (MAP) synthesis, and Enzyme-Linked Immunosorbent Assay (ELISA) development. Results: Twenty epitopes were identified, with two being in the signal peptide, five in the catalytic domain (CD), seven in the HBFT domain, and five in the receptor-binding domain (RBD). Two 17 mer (CB/Tx-2/12 and CB/DTx-4–13) derived biepitope peptides linked by a Gly-Gly spacer were chemically synthesized. The peptides were used as antigens to coat ELISA plates and assayed with human (huVS) and mice vaccinated sera (miVS) for in vitro diagnosis of diphtheria. The assay proved to be highly sensitive (99.96%) and specific (100%) for huVS and miVS and, when compared with a commercial ELISA test, demonstrated a high performance. Conclusions: Our work displayed the complete picture of the linear B cell IgG response epitope of the DTx responsible for the protective effect and demonstrated sufficient specificity and eligibility for phase IIB studies of some epitopes to develop new and fast diagnostic assays.
Detsko-youthful movement «Warmia» in the system of Patriotic education of children and youth
Authors: Lukina Antonida , Bulankov Valentin
Published: March 2021

The article analyzes the activity of the children's and youth movement "Yunarmiya" as a space for Patriotic education of teenagers and youth. It is shown that the conditions prevailing in the organization correspond to the age conditions and needs of adolescents and ensure the effectiveness of Patriotic education.
National projects, socio-economic policy and public equilibrium
Authors: Ustinovich Elena , Kulikov Michael
Published: March 2021

The article presents a brief analysis of modern economic policy in Russia. Attention is paid to the role of the Central Bank of the Russian Federation in public welfare and its role in the effectiveness of the social policy of Russia as a democratic state. Critical opinions of famous political scientists and economists on the role of the Central Bank of the Russian Federation in these processes are presented.
Party competition in the Republic of South Ossetia, on the eve of the VI convocation parliamentary elections
Authors: Lekov Ruslan
Published: March 2021

The dynamics of political processes and electoral competition in South Ossetia is explained by the high politicization of society. Without exaggeration, the majority of the population of the Republic was involved in the formation of party and political construction. The article analyzes the resource potential of key political parties, which gives us an understanding of how competitive the election campaign was in the elections to the VI convocation of the Parliament.
TRANSFORMATION OF EDUCATION AS A SYSTEM OF PREPARING A PERSON FOR LIFE UNDER THE INFLUENCE OF SOCIO-CULTURAL DYNAMICS OF THE XXI CENTURY
Authors: Kit Mykhailo
Published: March 2021

Radical changes in the world order, new trends in the economy, culture, political and legal relations require a revision of the paradigmatic foundations of education in the XXI century. Solving this problem is a very important task, because the education system provides the formation of civic, professional, moral and other qualities that contribute to the formation of the individual as a member of a particular social community.
The close relationship between values and the process of forming value orientations with educational practices is one of the most important basic constants of the interdependence of education and spiritual values. Trying to identify and explain the main trends of socio-cultural change in the XXI century, scientists use several basic theoretical models, which in turn allows us to see possible directions for updating the educational system.
Number of new socio-cultural phenomena in the XXI century need their further scientific understanding and clarification of their impact on educational processes.
DEVELOPMENTAL POTENTIAL OF ARTISTIC SYNTHESIS IN THE ART EDUCATION OF A FUTURE TEACHER
Authors: Malytska Olena
Published: March 2021

The synthesis of the arts is not the latest concept, but at the beginning of the XXI century it acquired a unique, compared to other eras, role in the artistic culture of modern society. Modern artistic practices are characterized by new synthetic properties, and therefore approaches to the mastery of modern teachers of modern art forms should take into account the relevant features of perception of works of art and synesthetic features of the process of artistic creation. Updating the technologies of art education and its methodological basis in the context of artistic synthesis is a factor in effectively solving the problems of artistic training of future teachers.
EDUCATION IN THE REALITIES OF THE MEDIA SPACE: A PHILOSOPHICAL UNDERSTANDING OF PROSPECTS
Authors: Podoliakina Olga
Published: March 2021

The article analyzes the extent to which social reality can be considered as constructed. The main causes and consequences of the media's influence on the construction of social reality are analyzed. The main risks and benefits of the influence of the media on education are identified and the main directions of constructive interaction between the media and education are indicated.
METHODOLOGY OF SOCIAL TEACHING OF THE ECUMENICAL PATRIARCHATE
Authors: Gulyamov Bogdan
Published: March 2021

Orthodox social doctrine as a discipline is formed without the elements of scholastic thinking that are characteristic of Catholicism. This is due to the fact that social doctrine in Orthodoxy is thought of as an expression of tradition, not the teaching of the church. Also, the methodology of the social doctrine of the Ecumenical Patriarchate was significantly influenced by the fact that the initial principle for all reflections was the value of the dignity of the individual. The absolutization of this value has made it possible to create a Christian humanism that opposes the ideological extremes of modern cultural wars, including the abuse of the idea of human rights. The ROC uses methodological anti-scholasticism in the construction of social doctrine to legitimize the ideas of Orthodox fundamentalism. Against this background, the social doctrine of the Ecumenical Patriarchate is becoming a worldview alternative, critical to the development of Ukrainian theology and education.
ИСТОРИЈСКИ ИНСТИТУТ 1947–2017. ГОДИНЕ
THE INSTITUTE OF HISTORY 1947-2017.
Authors: Поповић Радомир , Столић Ана
Published: March 2021

UDC 93/94 ISNN 0350–0802

DOI: 10.34298/IC1766013P

UDC: 94(497.11)„1917“(093.3)

pp. 13-25

language: serbian
КРИЗА ПАРЛАМЕНТАРНОГ СИСТЕМА У КРАЉЕВИНИ СРБИЈИ ОД 1892. ДО 1894. ГОДИНЕ
THE CRISIS OF THE PARLIAMENTARY SYSTEM IN THE KINGDOM OF SERBIA FROM 1892 TO 1894
Authors: Пешић Мирослав , Младеновић Божица
Published: March 2021

Апстракт:
У раду је приказана криза парламентарног система у Краљевини Србији од 1892. до 1894. године. Тешка политичка криза настала после образовања мањинске либералне владе Јована Авакумовића1 августа 1892. године озбиљно је угрозила парламентарни режим владавине. Оштре унутрашње политичке борбе праћене низом државних удара јасно потврђују тежњу ка личној власти младог монарха, који се тешко могао помирити са политичком доминацијом Радикалне странке. Краљ Александар Обреновић био је у сталној борби против тежњи Радикалне странке да уз помоћ Народне скупштине права владара што је могуће више ограничи.2

Кључне речи:
парламентаризам, Радикална странка, Намесништво, Никола Пашић, краљ Александар Обреновић.
“OUT OF THE EAST CHRIST CAME”: SERBIA IN THE EYES OF AMERICAN WOMEN IN THE GREAT WARж
„ХРИСТОС ЈЕ ДОШАО СА ИСТОКА“: СРБИЈА У ОЧИМА АМЕРИКАНКИ У ВЕЛИКОМ РАТУ
Authors: Вучетић Биљана
Published: March 2021

Abstract:

This paper is based on research into American magazine accounts of Serbia, as well as on reports on Serbia made by eyewitnesses, American journalists, and humanitarians who visited Serbia. Many of them made a large contribution to the formation of a positive image of Serbia and above all, of the Serbian people. A special emphasis is placed on the discourse and activism of three American women, who were personally and professionally linked to Serbia in the years of the Great War. Demetra Vaka Brown in 1917 considered political commentary a central part of her work, and her commentaries on politics during WWI were especially in demand. Amelia Peabody Tileston was a humanitarian, whose letters are abundant in data on Serbia, its people and soldiers, and the atmosphere at the Salonica Front. Another American who witnessed the ravages of war in the Balkans after WWI was Rose Wilder Lane who was sent to the Balkans by the Red Cross to investigate conditions there.

Keywords:

First World War, Serbia, America, women, Amanda Peabody Tileston, Demetra Vaka, humanitarian work.
HUBUNGAN KOMUNIKASI VERBAL DAN NON VERBAL PERAWAT DENGAN TINGKAT KEPUASAN PASIEN RAWAT INAP DI RUMAH SAKIT JUANDA KUNINGAN
Authors: Puspanegara Aditiya , Apriyanti Suci
Published: March 2021

Berdasarkan hasil wawancara dengan pasien di Rumah Sakit JuandaKuningan masih ada pasien merasa tidak puas dalam pelayanannya. Komunikasiverbal dan non verbal yang dilatih secara terus menerus melalui kemampuanbelajar mandiri, penyegaran dan pelatihan.Tujuan dari penelitian ini adalah untuk mengetahui hubungan komunikasiverbal dan non verbal perawat dengan tingkat kepuasan pasien rawat inap diRumah Sakit Juanda Kuningan Tahun 2020.Jenis penelitian ini adalah penelitian analitik dengan rancangan crosssectional. Populasi dalam penelitian ini adalah pasien rawat inap ruang RPU 3 diRumah Sakit Juanda Kuningan bulan Januari sampai Maret 2020 rata-rata perbulan sebanyak 65 pasien. Teknik pengambilan sampel yang digunakan adalahTotal Sampling sehingga diperoleh 72 pasien. Instrumen dalam penelitian adalahkuesioner. Teknik analisis data yang digunakan adalah analisis univariat dananalisis bivariat.Tidak ada hubungan komunikasi verbal dan non verbal perawat dengantingkat kepuasan pasien rawat inap di Rumah Sakit Juanda Kuningan Tahun 2020.Berdasarkan hasil penelitian ini, disarankan Rumah Sakit hendaknya dalamrancangan dan membuat kebijakan pelayanan keperawatan dalam memenuhikebutuhan pasien agar terciptanya kepuasaan pasien.
MODEL PREDIKSI KEPADATAN LALAT DI PASAR KABUPATEN KUNINGAN JAWA BARAT INDONESIA
Authors: Rahim Fitri Kurnia , Rohmatunisa Rika , Amalia Icca Stella
Published: March 2021

Sanitasi Pasar merupakan hal yang perlu diperhatikan karena pasar merupakan tempat berkumpulnya banyak orang. Kondisi sanitasi yang kurang baik seperti sampah yang berserakan dan tidak dikelola dengan baik dapat menimbulkan perkembangan vektor lalat. Vektor lalat dapat menyebabkan masalah kesehatan seperti kolera, tifus, diare dan penyakit gangguan pencernaan bagi masyarakat. Tujuan penelitian ini adalah menganalisis korelasi timbulan sampah dengan kepadatan lalat serta model prediksi kepadatan lalat di Pasar Kabupaten Kuningan. Penelitian ini merupakan penelitian observasional analitik dengan rancangan cross sectional. Penelitian dilakukan di pasar se-Kabupaten Kuningan pada bulan Juni-Agustus tahun 2020. Populasi penelitian ini adalah seluruh pasar yang ada di Kabupaten Kuningan, jumlah sampel pada penelitian ini adalah 31 pasar yang diambil berdasarkan total sampling. Variabel dependen pada penelitian ini adalah kepadatan lalat, variabel independen adalah timbulan sampah. Instrumen penelitian yang digunakan adalah adalah lembar observasi, bak sampah ukuran 20 x 20 x 100 cm, timbangan gantung digital dan fly grill berwarna kuning ukuran 100 x 100 cm. Pengumpulan data dilakukan dengan cara observasi ke setiap TPS pasar. Analisis bivariat dilakukan dengan uji Korelasi Person dan Multivariat Regresi Linieer. Hasil penelitian menunjukan rata-rata kepadatan lalat di Pasar Kabupaten Kuningan adalah 22,35 ekor/block grill  dan rata-rata jumlah timbulan sampah Pasar di Kabupaten Kuningan adalah 1,1879 kg/pedagang/hari. Terdapat korelasi (r) yang signifikan antara timbulan sampah dan kepadatan lalat dengan nilai r 0,703. Model prediksi kepadatan lalat yaitu dengan rumus persamaan (Y) = 1,006 + 17,971 (X), atau Kepadatan lalat = 1,006 + 17,971 (timbulan sampah). Adanya korelasi positif antara jumlah timbulan sampah dengan tingkat kepadatan lalat. Model prediksi menunjukan jika adanya penambahan 1 % timbulan sampah, maka kepadatan lalat akan meningkat sebesar 17,971. Dengan demikian, pihak pengelola pasar perlu melakukan upaya penyehatan lingkungan pasar khususnya di area tempat pembuangan sampah sementara serta melakukan pengendalian terhadap kepadatan lalat.
Inkoatibo/arazle alternantzia euskaraz eratortzen
Authors: Berro Urrizelki Ane , Oihartzabal Beñat , Fernández Fernández Beatriz
Published: March 2021

Lan honetan, euskarazko aditzen inkoatibo/arazle alternantzia arakatu dugu. Proposatzen dugun analisian, inkoatibo/arazle alternantzia Boza alternantzia da: Bozak espezifikatzaile bat islatzen duenean, aldaera arazlea sortzen da; bestalde, Bozak argumenturik ez duenean espezifikatzaile gunean, aldaera inkoatiboa dugu. Wood-i (2016) jarraituz, alternantzian aurkitzen diren hutsuneak erroen interfaze-jarraibideei egotzi dizkiegu, eta batzuek dituzten esanahi idiosinkrasikoak erro-alosemiaren bidez azaldu ditugu. Azkenik, ergatibo subjektuaren rola eta arazle esanahia sintaxi konfiguraziotik eratortzen direla proposatu dugu, eta ez buru sintaktiko jakin baten islapenetik.
Kriteria-Kriteria Pemancangan yang Mempengaruhi Pengambilan Keputusan pada Pemilihan Jenis Driven Pile dan Metode Pemancangan
Authors: Sari Oryza Lhara , Putri Andina Prima , Khala Christianto Credidi Septino
Published: March 2021

Pengambilan keputusan membuat praktisi berhadapan dengan berbagai kondisi yang mempengaruhi pemilihan jenis tiang dan metode pemancangan. Penelitian ini bertujuan untuk mengkaji kriteria-kriteria pemancangan yang mempengaruhi pemilihan jenis driven pile dan metode pemancangan yang optimal. Konseptual model disajikan sebagai model teoritis dari literature review yang dilakukan. Survei pendahuluan dilaksanakan dengan mengidentifikasi kriteria dengan wawancara kepada empat expert yang berpengalaman melakukan pekerjaan pemancangan pondasi. Kriteria yang telah diidentifikasi oleh expert digunakan untuk survei kuesioner. Survei kuesioner dilakukan kepada 45 responden praktisi yang pernah melakukan pekerjaan pemancangan pondasi di Balikpapan. Analisis yang digunakan untuk mengetahui kriteria yang berpengaruh adalah analisis deskriptif, uji nonparametrik (Kruskal-Wallis), uji validitas dan reliabilitas. Hasil mendapatkan tiga variabel utama yang meliputi kriteria pemancangan, jenis driven pile dan metode pemancangan. Enam kriteria pemancangan penentu yang didapatkan yaitu karakteristik tanah, kondisi lapangan, karakteristik bangunan, biaya, waktu dan pengalaman sebelumnya.
Design of a wide-angle compound eye acoustic lens system suitable for multi-user underwater acoustic communication
Authors: Sato Yuji , Ebihara Tadashi , Mizutani Koichi , Wakatsuki Naoto
Published: March 2021

Mobile underwater acoustic (UWA) communication is expected to enable advanced, efficient, and reliable underwater exploration. However, crosstalk among terminals occurs when multiple vehicles emit signals at the same time. In this paper, we propose a UWA lens that has the potential to achieve space-division multiple access by avoiding crosstalk between signals that come from a different angle. Specifically, we used wave theory to design a wide-angle compound eye lens and a hydrophone array geometrically. The two-dimensional finite-difference time-domain method was used to calculate wave propagation. Multi-user communication using a single-carrier scheme (two sources emit the signal simultaneously) was simulated with the designed lens system. The communication method with the lens system showed superior performance to that without the lens system. Additionally, the performance was improved by inserting partitions between lens segments.