bluuebunny/crossref_metadata_2025 huggingface dataset:
SYRINGOMYELIA IN NEUROMYELITIS OPTICA SEROPOSITIVE FOR AQUAPORIN-4 ANTIBODY: A CASE REPORT
Authors: Nina Grace Q. Bastinen , MD Maria
Published: November 2021

Neuromyelitis Optica (previously called Devics disease) is an autoimmune-induced demyelinating disorder of the central nervous system that primarily affects the optic nerves and spinal cord. This manuscript presents a case of a 28-yearold female patient who clinically presented with acute lower extremity weakness and numbness associated with unilateral impairment of vision. Later in the course of the disease, magnetic resonance imaging of the cervico-thoracic spine showed multi-level abnormal non-enhancing and enhancing lesions from levels C3 to T8 levels which were identified to be combined transverse myelitis and cord syrinx. An anti-aquaporin-4 receptor antibody was obtained and yielded to be seropositive. Given the patients clinical manifestations, combined with imaging and laboratory examinations, led to a diagnosis of Neuromyelitis Optica (NMO). The patient was managed with high-dose steroids. The significant discovery of anti-aquaporin-4 antibodies served as a key factor in the NMO immunopathogenesis. It is currently regarded as a specific biomarker of the diagnostic process, making it distinguishable from multiple sclerosis. This case highlights the mechanism of formation of a fluid-filled syrinx-like cavity in the cord in the setting of Neuromyelitis Optica.
SCREENING POLICIES FOR OVARIAN CANCER IN NIGERIAN HOSPITALS: A REVIEW
Authors: Odosa Agbonifo Worship
Published: November 2021

Ovarian Cancer is a problem battled worldwide and is typically diagnosed at an advanced stage due to the lack of effective screening strategies. An effective screening method should detect the disease at an earlier stage at diagnosis such that treatment would result in better outcome and not the inevitable mortality. Diagnosis of Ovarian cancer at an early stage (stage 1) could be a benefit of good screening strategies because it is associated with a high 5- year survival rate (95%) as it appears that globally, there is no early detection for this yet. In this article, we review the epidemiology, risk factors as well as the current state of screening tests for ovarian cancer in Nigeria.
SELF-EFFICACY AND ATTITUDE AS PREDICTORS OF MATHEMATICS PERFORMANCE OF SENIOR HIGH SCHOOL STUDENTS
Authors:   GEPS, Romblon State University, Odiongan, Romblon, 5505 Philippines., A. Fetalver Jr. Ph.D. Mario , M. Merano Edfelmar ,   GEPS, Romblon State University, Odiongan, Romblon, 5505 Philippines.
Published: November 2021

This study determined the relationship of self-efficacy, attitude, and performance in mathematics of senior high school students. Specifically, the study (a) described the level of mathematics self-efficacy of studentrespondents in terms of mastery experience, vicarious experience-peers, vicarious experience-adults, social persuasions, and physiological state, (b) characterized the attitude of the student-respondents towards mathematics in terms of anxiety, confidence, enjoyment, and benefits/value, (c) described the mathematics performance of the respondents, (d) determined the significant relationship between self-efficacy, attitude, and mathematics performance of the respondents, and (e) determined the predictors of students mathematics performance. Simple random sampling was used in identifying the 229 samples from three (3) public secondary schools offering senior high school in the Tablas Island. The researchers used the validated Self-Efficacy and Attitude towards Mathematics questionnaire. It was found out that the student-respondents have moderate mathematics self-efficacy in mastery experience, vicarious experience-peers, vicarious experience-adults, social persuasions, and physiological state. It was also found out that there was a high level of attitude towards mathematics in terms of benefits/value and moderate level of attitude towards mathematics in terms of anxiety, confidence, and enjoyment. Majority of the student-respondents did not meet the expectations in terms of mathematics performance, but a significant percentage of the group was average in the acceptable range of rating as significant relationship exists between self-efficacy, attitude and mathematics performance. The study revealed that the mathematics performance was predicted by variables such as vicarious experience-adults, benefits/value, anxiety, and vicarious experience-peers.
PREVALENCE OF ACUTE DIARRHEAL DISEASES AND ASSOCIATED RISK FACTORS AMONG UNDER FIVE CHILDREN IN AN URBAN SLUM OF MUMBAI
Authors:   Taluka Health Officer, Public Health Department, Wardha, M.S., Bele Swapnil , Suryawanshi S.R. ,   Professor and Head of Department, Community Medicine, T.N.Medical College, Mumbai., Palve Shailesh ,   Assistant Professor, Community Medicine, Govt Medical College, Aurangabad.
Published: November 2021

Introduction: Diarrhoea is one of the single most common causes of death among children under age five worldwide. Diarrheal disorders in childhood account for a large proportion (18%) of childhood deaths, with an estimated 1.5 million deaths per year globally, making it the second most common cause of child deaths worldwide1.So the study was undertaken in order to study the prevalence and associated risk factors causing diarrhoea in urban slum of Metropolitan city. Methods- A cross sectional study was done from January 2012 to December 2012 in Cheetah Camp area. Toal 478 under five children were selected and the parent/guardian of the child was interviewed using pre-designed, semi-structured and pre-tested questionnaires. Results and Conclusion-The prevalence of diarrhoea in children under 5 years during past 2 weeks was 17.8%. Diarrheal episodes in the past 2 weeks was significantly associated with education of mother, socioeconomic status of family, type of family, source of water supply, housefly nuisance in home, child hand-washing before meals, mother hand-washing before meals and immunization status.
ROLE OF IVERMECTIN IN THE TREATMENT OF COVID 19
Authors:   Pharm D intern Vignan Pharmacy College, Pin Code 522213, Vadlamudi, Guntur., Sandhya Rani Dindi , Indu Radha Chinta ,   Pharm D intern Vignan Pharmacy College, Pin Code 522213, Vadlamudi, Guntur., Supriya Vajrala ,   Pharm D intern Vignan Pharmacy College, Pin Code 522213, Vadlamudi, Guntur., Sai Sivani Anumolu ,   Pharm D intern Vignan Pharmacy College, Pin Code 522213, Vadlamudi, Guntur., S. Gottipati Satheesh ,   Department of Pharmacy Practice Vignan Pharmacy College, Pin Code 522213, Vadlamudi, Guntur., Srinivasbabu P. ,   Department of Pharmacy Practice Vignan Pharmacy College, Pin Code 522213, Vadlamudi, Guntur.
Published: November 2021

In vitro, ivermectin, an anti-parasitic drug licenced by the US Food and Drug Administration, was found to limit the replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).The three groups had similar clinical symptoms of fever, cough, and sore throat. When compared to the placebo group, virological clearance was faster in the 5-day ivermectin treatment arm (9.7 days vs 12.7 days p = 0.02), but not in the ivermectin Plus doxycycline arm (11.5 days p = 0.27). In the research, there were no serious adverse medication reactions. Adult patients with mild COVID-19 were treated with a 5-day course of ivermectin, which was proven to be both safe and efficacious. To corroborate these early findings, larger trials will be required.
A CRYSTAL CHEMISTRY OF HYDROXYAPATITE : A REVIEW
Authors:   Faculty of Science, Dr. Rammanohar Lohia Avadh University, Ayodhya-224001, (UP), India., Prakash Mishra Shiv
Published: November 2021

In chemistry of inorganic crystals, the octacalcium phosphate (OCP) is an apatite based crystals and having a hydrated layers which used in producing of needle or plate-shaped hydroxyapatite (HAP) nanocrystals. Although, the crystals is prepared by a dissolution precipitation reaction. These reaction led to a hexagonal HAP nanocrystals formation under hydrothermal condition from OCP at 180 for 3 hours with pH of solution adjusted to 5.5 and incorporating dicarboxylate e.g. succinate (OOC.(CH2)2.COO)2- ions having Ca/P molar ratio is expected to be 1.56Â±0.02, where the morphology of OCP are retained. During incorporating of succinate ions in OCP crystals, the hydrogen phosphate (HPO42-) ions in the hydrated layers of OCP are being substituted by succinate ions. Since the crystal system of HAP is hexagonal and its crystalline size in the longitudinal direction of various (a,b,c) axes depending on the thickness of the laminated plate-shaped HAP crystals. Here, their size as perpendicular to the (100) plane which is calculated by introducing of Scherrers equation, D100 = KÎ»/(Î² cos ). The organically modified OCP which generated to HAP have unique nanostructure with micrometer thickness are characterized by using of SEM, FTIR and X-ray diffraction analysis.
CUTANEOUS MICROABSCESSES BY MYCOBACTERIUM CHELONAE : CASE REPORTS FROM A TERTIARY CARE CENTRE, TRIPURA
Authors:   Associate Professor, Dept of Microbiology, AGMC & GBP Hospital, Tripura, India., Bhattacharya Sibabrata , Banik Ashmita ,   Post Graduate Trainee, Dept of Microbiology, AGMC & GBP Hospital, Tripura, India., Majumdar Tapan ,   Professor & HOD, Dept of Microbiology, AGMC & GBP Hospital, Tripura, India., Das Banti ,   Microbiologist, Dept of Microbiology, AGMC & GBP Hospital, Tripura, India.
Published: November 2021

Nontuberculous mycobacterial (NTM) infections are on the rise. They often cause skin diseases that are misdiagnosed.Two cases of Mycobacterium chelonae infection in immunocompetent patients were presented. First case showed infection of cutaneous and subcutaneous tissue without any preceeding history of skin injury by any intervention like trauma or injection, which was a rare manifestation. The second case showed M chelonae infection as a port site infection in a non healing ulcer. The history and clinical presentation of both the cases were documented. Treatment was also reported with subsequent output during further follow ups. Here both the cases showed resistance to commonly used amtimicrobial agents which increased the suspicion of nontuberculous mycobacterial infection among clinicians and microbiologist and made the diagnosis easier.
General Education Teachers’ Perceptions of the Real Engagement in Active Problem Solving (REAPS) Model
Authors:   University of British Columbia, Wu I-Chen , Pease Randy ,   The University of Arizona, Maker June ,   The University of Arizona
Published: November 2021

The purpose of this study was to explore general education teachers’ perceptions of their experiences while implementing the Real Engagement in Active Problem Solving (REAPS) model. REAPS is an evidence-based teaching model for challenging and engaging gifted students in a variety of settings. Twenty-three teachers answered 7 semi-structured questions. Using a general inductive approach, three coders with extensive experience in education analyzed the data by conducting independent parallel coding. The core theme, Student-Teacher Involvement in the Process of Discovery, was identified as the teachers' perceptions of the REAPS model. The responses were in three main categories: (a) Creating Meaningful Learning-Teaching Experiences, (b) Bridging the Knowing-Doing Gap, and (c) Increasing Learning Effectiveness. Each category included three to four identified subcategories to describe a specific phenomenon from teachers’ responses. Discussion included the core theme and its relationships with the categories and sub-categories. Ways to implement REAPS in classrooms and as a school-wide approach are discussed.
Abstract Knowledge, Embodied Experience: Towards a Literary Fieldwork in the Humanities
Authors:   Doctoral Student, Department of Humanities & Social Sciences, Indian Institute of Technology Roorkee, Roorkee, India., Rakshit Nobonita
Published: November 2021

The paper attempts to read the representation and (re)creation of Sundarbans into the narrative structure of the three works of Amitav Ghosh- The Hungry Tide (2004), Gun Island (2019), and Jungle Nama: A Story of the Sundarban (2021) through the idea of ‘literary fieldwork’ that the paper develops by putting these literary narratives in conversation with the fieldwork narratives. Drawing from Puri and Castillo’s (2016) concept of “humanities fieldwork” and Ghosh’s (2016) idea of sensuous recognition and identifying the literary texts as primary data for fieldwork, the paper brings home a new reading practice which here qualifies not only the role of Ghosh, the literary ethnographer but also the natives of Sundarbans who narrate their own testimonies of the place and their politics of survival. Their embodied experiences of Sundarbans are embedded with the author’s literary experiments in the texts to advance the place of fieldwork in literary studies and redefine the ideas of fieldwork in the humanities in general. In other words, the paper dwells upon the author’s creative response in portraying the difference between the abstract knowledge of the Sundarbans and the embodied experience of the place that offers literary fieldwork within which it accommodates the points of view of the author, the natives, and the readers and thus, changes the conventional practices of perceiving fieldwork in humanities.
Indigenous “People” in the context of the Right to Self Determination: A Critical Appraisal
Authors:   Asst. Professor, School of Law, KIIT University, KIIT University, Bhubaneshwar, Orisha., Dutta Mitul , Sinha Navin ,   School of Business and Law, Navrachna University, Navrachna University, Vadodara, Gujarat.
Published: November 2021

Under the international human rights regime, the right to self-determination is a right guaranteed to the groups of “people”. This right is one of the most controversial issues of international law as it comes into conflict with the principle of sovereignty and territorial integrity of the states. There are various uncertainties associated with this right regarding the scope of the right and mode of implementation etc. The present article seeks to make an in-depth analysis of the claimants of the right and the uncertainties associated with the meaning of the term “people” in the context of the right to self-determination. The article encompasses, among other things, the right of indigenous people under various international instruments and how they interrelate to the right of self-determination.
Bimala in Ghare-Baire: Tagore’s New Woman Relocating the “World in Her Home”
Authors:   Professor-English, University of Engineering and Management, New-Town, Kolkata. West Bengal, Banerjee Ayanita
Published: November 2021

The character of Bimala in Tagore’s Ghare- Baire or The Home and the World as a symbol of struggle for the liberation of Bengali woman as well as Bengal remains at the centre of scholarly discussion since the publication (1916), translation (1919) and the film adaptation (1984) of the novel. Bimala, the main protagonist of the novel is presented as a native Indian woman who gets western education and lives a modern lifestyle due to her marriage. She has conflicting attitudes, feelings and thoughts which recur randomly in the narrative. The paper focusses on the character of Bimala and interrogates the location of her agency with respect to the rising Swadeshi movement and the political excesses on one hand and her relationship with Nikhil and Sandip on the other. On a further note, reflecting on the political and epic underpinnings of Bimala (caught between the gradual and the radical approach to Swadeshi), the paper intends to stretch beyond her “situation” (the apex of the triangular relationship) and explore her self-realization at the end of the novel. Bimala, the woman set between the option of choices between the ‘motherland’ and the ‘two-men’ gradually transgress from the shackles of her naïve identity to become the beset New Woman. To explore Tagore’s rewritten epic of a woman (epitomized in real life as the New Woman), we need to discuss how the writer helped shaping the image of the New Woman through his conscious evoking of Bimala in the role of Sita, Nikhil in the role of Rama and Sandip in the role of Ravana. In response to the popular inscriptions of Bharatmata, Tagore allegorises the iconographic representation of Bimala resembling the “divine feminine strength (Shakti)for creation and (Kali) for the cause of destruction.” (Pandit 1995,217-19).
Relocating Colonial Women in Resistance: An Interpretation of Rabindranath Tagore’s Nastanirh and Chaturanga
Authors:   Junior Research Fellow (UGC), Manipal Institute of Communication, Manipal Academy of Higher Education, Manipal, India, Krishnapriya T. K. , Rani Padma ,   Director & Professor, Manipal Institute of Communication, Manipal Academy of Higher Education, Manipal, India;, Fraser Bashabi ,   Professor Emerita of English and Creative Writing, Director, Scottish Centre of Tagore Studies (ScoTs), School of Arts & Creative Industries, Edinburgh Napier University, Edinburgh
Published: November 2021

The Colonial Bengal of the nineteenth and twentieth centuries was a place of contradictions. For instance, despite certain evident advancements in the resolution of the women’s question, some of the emancipatory attempts of the period marked a rather dubious account of women’s liberation as patriarchal underpinnings hegemonized the efforts. Amid this complex backdrop, the colonial women’s position is further jeopardized by the western feminist scholarship that contrives colonial third world women as perennial victims and beneficiaries of emancipatory actions from the West. The paper attempts to relocate the colonial women and their resistance by negotiating the fissures in their construction. This study, informed by bell hooks’ (1990) postulations on margin and resistance, simultaneously seeks to form a bridge between the experiences of marginalized women beyond borders. Rabindranath Tagore’s Nastanirh (1901) and Chaturanga (1916) are chosen for close textual reading to examine the experiences of colonial women. The author’s women protagonists often embody the social dilemma of the period. Tagore’s Damini and Charu exist in the margin of resistance whilst Nanibala occupies the margin of deprivation. Significantly, Charu and Damini traverse the precarious “profound edges” of the margin to imagine a “new world” free of subjugation. Thus, the resistance offered by these women subverts the predominant conceptions of victimhood of colonial women, and it enables them to be posited as active agents.
Gay Subculture and the Cities in India: A Critical Reading of Select Works of R Raj Rao
Authors:   PhD Scholar, Humanities and Social Sciences Department, IIT Kharagpur, West Bengal, India,, Das Sriya
Published: November 2021

In delineating the painful experiences of LGBTQ individuals after the introduction of Section 377 of the Indian Penal Code R Raj Rao’s works look into the struggle of these people to survive the onslaught of normative sexual discourses. Given the fact that Queer sexuality has been continuously questioned, suspected and tormented prior to its legitimate recognition in 2018, Rao draws attention to the nuances of gay urban life in India. The paper critically analyses the representation of gay subculture in the cities of India as reflected in select works of Rao. It demystifies how gay people share the urban space, manage to make room for their pleasure in the cities, and pose a threat to the dominant understanding of sexuality. The ultimate objective of this paper is to understand the role of the city in the (un)making of a subcultural identity. Textual analysis, with reference to certain theoretical frameworks, would be used as a qualitative research method.
Molecular Docking Approach of Viscosin as Antibacterial for Methicillin-resistant Staphylococcus Aureus Via Î²-Lactamase Inhibitor Mechanism
Authors: Syaban Mokhamad Fahmi Rizki , Erwan Nabila Erina , Raihan Syamsuddin Muhammad Rafif , Zahra Fatimah Az , Sabila Faradilah Lukmana
Published: November 2021

Background: Î²-lactamase is an enzyme that plays a role in the occurrence of antibiotic resistance against Methicillin-resistant Staphylococcus aureus (MRSA) bacteria. Viscosin is a lipopeptide biosurfactant produced by the Pseudomonas group bacteria. A study states that Viscosin has strong antibacterial properties.Aims: This study aims to determine the interactions that occur with Viscosin and Î²-lactamase enzymes.Methods: Researchers used the in-silico method to determine the molecular interactions that occurred computationally. The protein used was Î²-lactamase protein obtained from the Protein Data Bank and Viscosin ligand obtained from the PubChem web server, and we used native ligands as control. Pharma expert web server and Pyrx, Pymol, and Discovery Studio software were used in this research.Results: The results showed that Viscosin has high activity as an antibiotic and is predicted to be a membrane integrity antagonist. The binding affinity interaction that occurs between Viscosin-Î²-lactamase is -7.3 kcal/mol. The affinity is lower than the control.Conclusion: Viscosin was predicted to have strong antibacterial properties, but the binding interaction was lower than the control. However, exploration of Viscosin compounds and further research to determine the antibacterial effect of Viscosin against MRSA and other bacteria is needed to against antibiotic resistance.
The Diagnosis Algorithm of Chronic Hypokalemia in Bartter Syndrome and Gitelman Syndrome: A Case Report
Authors:   General Hospital of Muhammadiyah Malang, Indonesia, Fajri Ro'di , Isbandiyah Isbandiyah ,   General Hospital of Muhammadiyah Malang, Indonesia, Pambudi Gusti ,   General Hospital of Muhammadiyah Malang, Indonesia
Published: November 2021

Introduction: Hypokalemia is common disorder characterized by low plasma potassium levels (<3.5 mEq / L). Hypokalemia can be caused by genetic disorders. Bartter syndrome and Gitelman syndrome are rare genetic disorders that cause damage to the tubular kidneys. The cause of hypokalemia must be determined by analyzing the diagnosis algorithm of hypokalemia. Case Illustration: A 27-year-old woman was brought to the emergency room with complaints of weakness in both legs since 1 day ago. Obtained a history of chronic hypokalemia since 5 years ago. No history of thyroid disease, and never taking diuretic drugs. The patient is calm. Vital signs: BP: 110/60, regular pulse 88x/minute, temperature: 36.7°C, respiratory rate 14x/minute, oxygen saturation 99% in room air. ECG showed Normal sinus rhythm with normal T wave. Laboratory findings showed severe hypokalemia with plasma potassium 1.7 mEq/L, increased urine potassium (71.1 mmol/24 hours), increased urine sodium 306 mmol/24 hours, and increased urine chloride (342 mmol/24 hours), plasma magnesium levels were normal (1.91 mg/dL). KCl infusion was given to correct electrolyte imbalance condition. Discussion: : Several examinations must be performed to confirm the cause of hypokalemia condition. The diagnosis of this patient was suspected to lead to Bartter syndrome and Gitelman syndrome, because there was an increase in urinary potassium excretion, normotensive conditions, no suspicion of metabolic acidosis, and no symptoms of nausea and vomiting and no history of diuretic drugs usage. Keywords: Hypokalemia, Bartter syndrome, Gitelman syndrome
Industrial experience in the implementation of clinker-free binders of alkaline activation
Authors: Salamanova M. Sh. , Ismailova Z. Kh.
Published: November 2021

Objective. Issues related to the search for new, less energy- and material- intensive binders have long been on the agenda of many world environmental forums, since the carbonate technology of Portland cement entails pollution of the surrounding atmosphere and habitat, and the price of this product is unjustifiably growing. In our opinion, alkaline cements could contribute to the construction industry. Within the framework of this work, research results have been obtained that confirm the effectiveness of the development of a clinker-free technology for producing alkaline-mixed binders and composites based on them using aluminosilicate additives, both natural and technogenic origin.

Method. The methods of electron microscopy and differential thermal analysis make it possible to study the nature of the components and the processes of formation of the structure of the cement stone. Waste from the cement industry has the appropriate granulometric and chemical composition, the aluminosilicate mineralogy of the studied powders confirms their compliance with the ready-made raw mix of Portland cement clinker, which is the key to the possibility of their effective use.

Result. The carried out differential thermal analyzes confirmed the presence of the following phases in the composition of cement stone on binding bonds "cement dust - alkaline activator" of zeolite, calcite, mica type muscovite, montrillonite, magnesium oxide, calcium sulfoaluminates, ettringite structure, calcium hydrochloraluminate, calcium hydrosilicate, calcium hydrosilicate calcium.

Conclusion. The obtained regularities of the processes of formation of the structure of the cement binder "waste of the cement industry - Na2SiO3", will transform these developments to create strong and durable artificial building composites competing with concretes on Portland cement.
Design of thermoelectric devices for extracting foreign objects from the human body by freezing
Authors: Evdulov O. V. , Nasrulaev A. M. , Kazumov R. Sh.
Published: November 2021

Objectives.The  purpose  of  the  article  is  to  consider  the  designs  of thermoelectric  devices  (TEC)  for  extracting  foreign  objects  (IO)  from  the  human  body  by freezing with various options for removing heat from the hot junctions of the thermoelectric module (TEM).

Method. Modifications of thermoelectric devices are described for extracting the IO from the human body by freezing it to a special probe. Their technical design differs in the way of heat removal from the TEM hot junctions, for which air heat removal, melting working substances and preliminary cooling of the radiator are used. The basic relationships for calculating the technical means intended for the removal of heat from the hot junctions of the TEM are presented.

Result. The graphs of the dependence of the temperature change of the TEM hot junctions in time are obtained for different values of its heat output when using an air heat removal system and the time of complete penetration of various working substances used in the device.

Conclusion. The data obtained show that for the operating conditions of the TEC, the temperature of the hot junctions of the TEM with an air heat sink does not go beyond the permissible limits. With a module power of 8 W, 12 W and 16 W, the temperature of the hot junctions of thermoelements stabilizes rather quickly and takes the value of 308 K, 313 K and 318 K. maintaining their stable temperature is most preferred is nickel nitrate, less - elaidic acid and paraffin. Calculations of the design of a device with a pre-cooled radiator system also show the efficiency of heat removal from the hot junctions of the TEM for the duration of the entire procedure for removing the IO from the human body.
Uniwersytet Kardynała Stefana Wyszyńskiego – nowoczesna uczelnia z tradycją
Authors: Bednarczyk Rafał
Published: November 2021

Uniwersytet Kardynała Stefana Wyszyńskiego w Warszawie jest jednym z młodszych uniwersytetów w Polsce. Jest to uczelnia państwowa, jednak posiada wyraźną tożsamość katolicką. Wynika to z faktu, że uniwersytet ten został powołany na bazie Akademii Teologii Katolickiej, będącej spadkobierczynią warszawskiej teologii akademickiej, związanej z powstałym w 1816 r. Uniwersytetem Warszawskim. Jego historia stanowi potwierdzenie, że we współczesnym, pluralistycznym społeczeństwie są potrzeb- ne uczelnie łączące styl nowoczesnego uprawiania nauki z głębokimi wartościami humanistycznymi oraz wiarą w Boga. Jest to prężna wspólnota akademicka realizująca wartości, którymi żył jej patron kard. Stefan Wyszyński służąc Bogu, Kościołowi, Ojczyźnie i człowiekowi.
Wybrane aspekty atrakcyjności gospodarczej i rozwoju przedsiębiorczości w miastach powiatowych subregionu siedleckiego w latach 2010–2019
Authors: Kucharska Agata , Piwowarczyk Dariusz
Published: November 2021

W artykule przeanalizowano wybrane elementy atrakcyjności gospodarczej miast powiatowych sub- regionu siedleckiego, rozumianego jako podregion statystyczny NUTS 3 siedlecki, położonego we wschodniej części województwa mazowieckiego. W ramach analizy scharakteryzowano najważniejsze uwarunkowania rozwoju gospodarczego tych miast, z uwzględnieniem powiązań komunikacyjnych i wyznaczonych terenów inwestycyjnych, a także najważniejsze aspekty działalności gospodarczej w przedmiotowych miastach, w tym największe przedsiębiorstwa oraz główne specjalizacje gospodar- cze. Przeanalizowane zostały wybrane procesy rozwojowe w zakresie przedsiębiorczości w latach 2010– 2019, a także wysokość funduszy unijnych pozyskanych przez beneficjentów z tych miast na projekty na rzecz poprawy konkurencyjności przedsiębiorstw.
Circulating Plasma Biomarkers in Biopsy-Confirmed Kidney Disease
Authors: Schmidt Insa M. , Sarvode Mothi Suraj , Wilson Parker C. , Palsson Ragnar , Srivastava Anand , Onul Ingrid F. , Kibbelaar Zoe A. , Zhuo Min , Amodu Afolarin , Stillman Isaac E. , Rennke Helmut G. , Humphreys Benjamin D. , Waikar Sushrut S.
Published: November 2021

Background and objectives

Biomarkers for noninvasive assessment of histopathology and prognosis are needed in patients with kidney disease.

Design, setting, participants, & measurements

Using a proteomics assay, we measured a multimarker panel of 225 circulating plasma proteins in a prospective cohort study of 549 individuals with biopsy-confirmed kidney diseases and semiquantitative assessment of histopathology. We tested the associations of each biomarker with histopathologic lesions and the risks of kidney disease progression (defined as ≥40% decline in eGFR or initiation of KRT) and death.

Results

After multivariable adjustment and correction for multiple testing, 46 different proteins were associated with histopathologic lesions. The top-performing markers positively associated with acute tubular injury and interstitial fibrosis/tubular atrophy were kidney injury molecule-1 (KIM-1) and V-set and Ig domain-containing protein 2 (VSIG2), respectively. Thirty proteins were significantly associated with kidney disease progression, and 35 were significantly associated with death. The top-performing markers for kidney disease progression were placental growth factor (hazard ratio per doubling, 5.4; 95% confidence interval, 3.4 to 8.7) and BMP and activin membrane-bound inhibitor (hazard ratio, 3.0; 95% confidence interval, 2.1 to 4.2); the top-performing markers for death were TNF-related apoptosis-inducing ligand receptor-2 (hazard ratio, 2.9; 95% confidence interval, 2.0 to 4.0) and CUB domain-containing protein-1 (hazard ratio, 2.4; 95% confidence interval, 1.8 to 3.3).

Conclusion

We identified several plasma protein biomarkers associated with kidney disease histopathology and adverse clinical outcomes in individuals with a diverse set of kidney diseases.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2021_12_28_CJN09380721.mp3
Building Inner Motivation among FL Learners in the Age of Education Globalization with the Help of New Technologies
Authors: Walczak Dominika , Polok Krzysztof
Published: November 2021

The main aim of this article is to present essential information concerning the correlation between building students’ inner motivation and using modern technologies for teaching and learning purposes. Mixed research was conducted including questionnaires, tests, lesson observation sheets, and focus group interviews. The respondents were divided into three age categories. However, all the students agree that lessons using modern technologies significantly affect the level of their internal motivation to work independently. The role of teachers is significant, as they should constantly deepen their knowledge in this field and teach their students how to use new technologies effectively.
Elective Affinities in the Anthropocene: Christianity and the Natural Environment Reconsidered
Authors: Burns Thomas J , Boyd Tom W , Hekmatpour Peyman
Published: November 2021

To reach a deeper understanding of the complex relationship between religion and the natural environment, it is important to move beyond essentializing any religious tradition as having a pro-environmental or anti-environmental ethic. Rather, prior work has shown that the canonical, scholarly, and popular literatures and discourse of a number of religious traditions can and have been socially and rhetorically constructed as supporting an array of positions, from preservation to profligacy, and much in between those two ideal types. In this paper, we develop Max Weber’s theory of “elective affinities” and adapt it to the Anthropocene, to make the case that in a fragmented society, people and communities of convenience tend to choose the tropes and framing from the dominant culture to justify self-interested action. That often can take the form of religious discourse. In the sense of finding a wide array of practical interpretations relative to the environment, the theory is largely supported, although we do find important nuances. It is instructive to look at how the language and legitimacy of one institution (e.g. religion) has been used to justify and legitimate that of others (e.g. the polity). While these processes of institutional co-optation can be effective in the short run, they may have corrosive longer-term effects. Key rhetorical, and in fact political, battles in the Third Millennium, will likely be organized around how to adapt pre-industrial religion to late industrial and perhaps post-industrial times, and it remains to see how central the natural environment will be in what communities hold sacred.
Los beneficios posicionales como Incentivo a la Corrupción Judicial
Authors: Seleme Hugo
Published: November 2021

Los diferentes mecanismos empleados para combatir la corrupción y garantizar la independencia de los jueces pueden producir efectos contradictorios. El trabajo muestra los efectos contradictorios que tiene la utilización de dos mecanismos usualmente empleados para combatir la corrupción: la concesión de altos beneficios posicionales a quienes ocupan cargos judiciales (básicamente los beneficios asociados con la remuneración y el salario), por un lado, y la selección de funcionarios dotados con ciertos rasgos de carácter que los vuelvan inmunes a la tentación de la corrupción, por el otro. Los mecanismos que hemos diseñado para garantizar la selección de individuos con estos rasgos de carácter ven amenazada su eficacia por la concesión de altos beneficios posicionales.
SRGM Dependent Learning based Testing Effort for Refinement
Authors: Firdose S. Rumana
Published: November 2021

Abstract: During the development of software code there is a pressing necessity to remove the faults or bugs and improve software reliability. To get the accurate result, in every phase of software development cycle assessments needs to be happen, so that in each phase early bugs detection takes place that leads to maintain accuracy at each level. The academic institutions and industries are enhancing the development techniques in software engineering and their by performing regular testing for finding faults in programmers of software during the development. New programs are composed by altered the original code by comprised more of a bias near statements that arise in pessimistic execution paths. Fault localization information technique is used in proposed method to indicate the position of fault. In experimental as well as regression based equations represent the soft computing techniques results is better compare to the other techniques. Evaluation of soft-computing techniques represented that accuracy of the ANN model is superior to the other models. Data bases for performing the training and testing stages were collected, these soft computing techniques had low computational errors than the empirical equations. Finally says that soft computing models are better compare to the regression models. Hence, finding faults and correcting a serious software problem would be better instead of recalling thousands of products, especially in automotive sector. SRGM success mainly reliable by gathering the accurate failure information. The functions of the software reliability growth model were predicted in terms of such information gathered only. SRGM techniques in the literature and it gives a reasonable capability of value for actual software failure data. Therefore, this model, in future, can be applied to operate a wide range of software and its applications. Keywords: SRGM, FDP, FCP
Elecciones argentinas 2019: Estudio de los nexos protagónicos en los spots del Frente de Todos
Authors: Cicowiez Mariano
Published: November 2021

En el artículo se examinan spots publicitarios divulgados en medios tradicionales de prensa, pertenecientes a la campaña de la coalición Frente de Todos para las elecciones argentinas de 2019. El análisis se focalizó en los seis términos del modelo mítico actancial de Algirdas J. Greimas, con el objetivo de reconocer un estilo de composición que involucra a los protagonistas, políticos y civiles, de los avisos partidarios. La metodología consistió en la elaboración de un corpus de unidades de observación que incluye al conjunto de spots difundidos en televisión abierta, sobre el que se efectuó un examen de las posiciones actanciales en razón de los enunciados verbales y de su diseño de composición visual. Esta perspectiva ha permitido reconocer, en mayor medida, dos posiciones adjudicadas a los ciudadanos que integran los spots, sujetas a la proximidad que intermedia entre los candidatos y los electores en el marco de una campaña de elección presidencial.
Reseña bibliográfica
Authors: Carmona Rodríguez Manuel
Published: November 2021

Ultrasaturados. El malestar en la cultura de las pantallas,de Juan Carlos Pérez Jiménez. Madrid: Plaza & Valdés, 2021. 228 págs.
Sabiedrības drošība
Authors:   Latvijas Universtāte, Kjakste Aleksandra , Struberga Sigita
Published: November 2021

Sabiedrības drošība apskata apdraudējumus sabiedrības vai tās daļu tradicionālajiem dzīvesveidiem, paražām, reliģiskajām praksēm, etniskajām un nacionālajām īpatnībām. Sabiedrības drošības dimensija pēdējā desmitgadē ir bijusi gan politiskajā, gan akadēmiskajā dienaskārtībā, tomēr līdz šim nav ticis veikts pētījums, kas ļautu integrēt indivīdu identificētos draudus to identitātei kopējā Latvijas iedzīvotāju draudu uztveres skatījumā un vērtēt iespējamās cēloņsakarības, kuras pastāv starp uztvertajiem draudiem un atbilstošām rīcībpolitikām kā atbildēm uz tiem. Šajā grāmatas nodaļā identificēti tie sabiedrības draudu veidi, kurus Latvijas iedzīvotāji uzskata par nozīmīgiem, kā arī apskatīts, vai un kā vietējās pašvaldības reaģē uz iedzīvotāju bažām par apdraudējumiem sabiedrības drošības dimensijā. Analīzes rezultātā secināts, ka Latvijas iedzīvotāji identificē draudus to unikālajai patībai un atzīst tos kā būtisku izaicinājumu savai drošībai. Visbiežāk tos satrauc imigrācija kā potenciālais apdraudējums viņu subjektīvā vērtējumā. Kopumā Latvijas sabiedrība tiek raksturota kā slēgta, uz tradicionālām vērtībām orientēta. Savukārt reģionos iedzīvotāji izjūt plaisu starp reģionu un galvaspilsētu un uzsver, ka pastāv atsevišķa, nošķirta dzīve un dienaskārtība un līdz ar to divas atšķirīgas kopienas. Rezultātā kā nozīmīgākos iekšējos apdraudējuma avotus sabiedrības drošības sektorā Latvijas iedzīvotāji nosaukuši citus iedzīvotājus vai to grupas, kā arī valsts pārvaldes iestādes. Savukārt pašvaldības bauda lielāku uzticēšanos. Kā ārējais apdraudējuma avots galvenokārt minēta Krievijas Federācija. Pašvaldību darbības analīze liecina, ka kopumā pašvaldības reti un ierobežotā apjomā saredz savu lomu drošības stiprināšanā sabiedrības drošības sektorā. No iegūtajiem rezultātiem secināms, ka sabiedrības pārstāvju, kā arī pašvaldību darbinieku iesaiste plašākās diskusijās par drošību, pilsonisko audzināšanu un iekļaušanu ir būtisks faktors sabiedrības drošības stiprināšanā ar noteikumu, ka šāda veida aktivitātes būtu domātas visu sabiedrības grupu iekļaušanai, nevis kādas grupas izslēgšanai, identitātes apdraudēšanai vai tās nozīmīguma noliegšanai.
Coffee Fun: Gamified Tool Based on the SUM Agile Development Methodology For Video Games
Authors: Jaramillo Reinel Manuel Esteban , Mera Tróchez Andrés Felipe , Márceles Villalba Katerine , Chanchí Gabriel Elías
Published: November 2021

In recent years, serious games have been applied in different contexts of application, highlighting their contribution in the educational context. This original type article presents the design, construction and evaluation of the Coffee Fun video game. Coffee Fun is a video serious game aimed at children aged 8 to 12 years old; the game has as a theme the growing of coffee beans in a simulation environment in which each player helps the growth of this plant by a few tools provided at each level of the game; in the game, different scenarios related to coffee growing environments are presented for each of its stages in a series of levels that the player must overcome to complete the game through a process of learning and entertainment.
The Great Imposter: A case Report of IgG4 RD -Hypertrophic Pachymeningitis with Skull Lytic lesion and Pulmonary Nodules
Authors: Wadiwala Muhammad , Ali Liaquat , Khan Adnan , alhatou Mohammed
Published: November 2021

Immunoglobulin G4-related disease is an inflammatory condition with
unique clinical, serological, and pathological features. Here, we report
a diagnostic challenging clinical case. Histopathology was used to
diagnose his Ig4RD. This unique inature reinforces the fact that it is
crucial to consider the diagnosis of IgG4-RD in those presenting with
pachymeningiti
Formal Female Entrepreneurship and the Shadow Economy
Authors: DiRienzo Cassandra E. , Das Jayoti
Published: November 2021

Although female entrepreneurship yields products, markets, and business models that might not exist otherwise and are relevant to economic growth and development as well as issues related to gender equality, the factors that drive female entrepreneurship is largely understudied. The primary objective of this study is to examine the relationship between the size of a country’s informal sector and the prevalence of female entrepreneurship in the formal economy. This relationship is empirically tested using a regression analysis that employs a cross-country data set of 70 countries. The analysis results indicate a significant inverse relationship between the size of the informal sector and the prevalence of formal sector female entrepreneurship. It is argued that a larger informal economy implies a greater number of women working in the informal sector due to discriminatory barriers to the formal economy. Both formal sector entrepreneurship and work in the informal economy can lessen the barrier to entry women face related to work-life balance by allowing greater flexibility in work hours; however, employment in the informal sector is a relatively poor substitute to formal sector employment as informal sector work does not include benefits, nor is it taxed or included in official statistics. Policy recommendations for encouraging formal female entrepreneurship are made. Promoting female entrepreneurship in the formal sector not only helps to close gender, inequality gaps, but also serves to improve tax systems, lessen distortions in national accounts and official indicators, and improve the provision of public goods.
The Effect of Black Tax on Employee Engagement: The Mediating Role of Idiocentrism-Allocentrism-A Case of Pharmaceutical Industry in Zimbabwe
Authors: E. Vakira, , D. Nikisi, , N. Ndlovu, , V. Shumba, , M. Ncube, C. , D. Mpofu, B.
Published: November 2021

Employees in the Pharmaceutical industry are coming late to work and knocking off early. These actions unveiled by the employees are likely to incur economic costs on the employer, occasioned by low employee productivity. Owners of production have expressed concern over the general low staff morale in the pharmaceutical sector. While most studies have concentrated on internal job-related factors as drivers of employee engagement, this study seeks to assess employee engagement as being influenced by black tax, an external factor. The main aim of the research was to establish the influence of black tax on employee engagement, being mediated by idiocentrism-allocentrism, particularly focussing on the pharmaceutical manufacturing and retailing industry in Bulawayo, Zimbabwe. The study employed the philosophical approach of pragmatism to guide the whole research. The researcher adopted a multi-stage sampling technique supported by the census technique to pick participants from the population. Closed and open-ended questionnaires were used to collect data from qualified pharmacists who are working in both the manufacturing and retailing industry in Bulawayo. Statistical Package for Social Sciences v23 (Process v3.5 by Andrew F. Hayes) was used to test the hypothesized relationship among variables. Qualitative data were analyzed using thematic analysis. The results suggest that black tax directly influence employee engagement in the presence of a mediator (idiocentrism-allocentrism). Furthermore, the results indicate that the indirect coefficient was partially significant, which means that idiocentrism-allocentrism has a partial influence on employee engagement. The researchers recommend that management should ensure that employees are motivated all the time. They should implement an open-door policy so that employees can share their issues that affect their engagement level at work.
Demographic Traits and Behavior of Hetaerina cruentata (Odonata: Calopterygidae) in Ecosystems of the Andean Region of Colombia
Authors: García-Monsalve María Vianney , Altamiranda-Saavedra Mariano , Rodríguez Fredy Palacino , Cordero-Rivera Adolfo
Published: November 2021

Demography and territorial behavior of Hetaerina cruentata was studied along three lowland streams located at Norte de Santander department in the Colombian Andean region. Adult damselflies (N: 278) were individually marked, and using their recapture histories we estimated survival, longevity, sex ratio, age groups and population size at each location. We found no evidence for survival differences between ages and sexes. However, the proportion of resighted individuals was lower for females, and the sex ratio was male-biased in all populations. Although we recorded few reproductive events, a high number of male-male agonistic interactions were registered around midday. During reproductive behavior, we observed brief wing displays as signals between males and females, and the formation of the tandem position, followed by the intra-male sperm translocation and copulation (mean duration 11.3 min). After copulation, the pair in tandem looked for suitable sites to oviposit, and then the male broke tandem and perched on the vegetation while the female laid eggs partially or completely underwater. The recapture probability was time-dependent, which suggests that the alternation of rainy and sunny days during the study may be generating differences in the demography of the three H. cruentata populations.