bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of High-Voltage Electrodes for Neutron Scattering Sample Environment Devices
Authors: Sun Guoliang , Guo Tingting , Yuan Bao , Yang Xiaojing , Wang Guang
Published: March 2024

The sample environment is essential to neutron scattering experiments as it induces the sample under study into a phase or state of particular interest. Various sample environments have been developed, yet the high-voltage electric field has rarely been documented. In this study, Bruce electrodes with various sectional geometries and chamber sizes were examined by using simulation modeling based on ANSYS Maxwell. A large uniform field region where samples would sit could be achieved in the planar region for all specifications, but the size of the region and the field strength varied with the gap distance between electrodes. The edging effect was inherently observed even for bare electrodes, about 1.7% higher in the sinusoidal region than the planar region, and was significantly deteriorated when a chamber was applied. This effect, however, presented an exponential decrease as the minimum distance between the electrode edge and the chamber shell increased. A compromise between the spatial confinement and the achievable field (strength and uniform region) could be reached according to the unique applicability of neutron instruments. This research provides a theoretical basis for the subsequent design and manufacturing of high-voltage sample environment devices.
Associations between Multiple Health Indicators and Carotid Artery Intima-Media Thickness in A Healthy and Active Elderly Population
Authors: Pfister Robin , Kaur Rajneesh , Maesom Gary , Hager Ronald L.
Published: March 2024

The purpose of this study was to examine correlations between health indicators (age, BMI, blood pressure (BP), functional strength (FS), handgrip strength, and predicted VO2 max) and carotid intima-media thickness (cIMT) in an active 50 years+ population. Study participants’ mean cIMT was also compared to the cIMT mean of the general population. Health screenings were conducted on 1818 participants at the Huntsman World Senior Games from 2016 to 2019. Pearson’s correlations, Spearman’s correlations, and ANOVA were performed using SPSS. Weak but significant correlations were evident between cIMT and age (r = 0.283, p < 0.001), systolic BP (r = 0.253, p = 0.001), diastolic BP (r = 0.074, p = 0.016), weight (r = 0.170, p < 0.001), height (r = 0.153, p < 0.001), handgrip L (r = 0.132, p < 0.001), handgrip R (r = 0.074, p < 0.029), and BMI (r = 0.07, p = 0.029); non-significant correlations were evident with predicted VO2 max (r = −0.035, p = 0.382), and FS (r = −0.025, p = 0.597). When controlling for age, systolic BP, and sex, only handgrip L (r = 0.225, p = 0.014) was significantly correlated with cIMT. Mean cIMT for this cohort was lower across all sexes and age-matched groups (cIMT = 0.6967 mm (±0.129)). Physical activity is linked to reduced cIMT. Most health-related indicators in this study were significantly but weakly correlated with cIMT. Additional research is needed before common indicators can be used as a surrogate for cIMT and CVD risk. Results from this study can provide clinicians with additional information to reduce CVD risk through modifiable risk factors. Classic CVD risk factors such as systolic BP and BMI should be considered in patients regardless of lifestyle.
Micro- and Macro-Scale Topology Optimization of Multi-Material Functionally Graded Lattice Structures
Authors: Santos Jerónimo , Sohouli Abdolrasoul , Suleman Afzal
Published: March 2024

Lattice structures are becoming an increasingly attractive design approach for the most diverse engineering applications. This increase in popularity is mainly due to their high specific strength and stiffness, considerable heat dissipation, and relatively light weight, among many other advantages. Additive manufacturing techniques have made it possible to achieve greater flexibility and resolution, enabling more complex and better-performing lattice structures. Unrestricted material unit cell designs are often associated with high computational power and connectivity problems, and highly restricted lattice unit cell designs may not reach the optimal desired properties despite their lower computational cost. This work focuses on increasing the flexibility of a restricted unit cell design while achieving a lower computational cost. It is based on a two-scale concurrent optimization of the lattice structure, which involves simultaneously optimizing the topology at both the macro- and micro-scales to achieve an optimal topology. To ensure a continuous optimization approach, surrogate models are used to define material and geometrical properties. The elasticity tensors for a lattice unit cell are obtained using an energy-based homogenization method combined with voxelization. A multi-variable parameterization of the material unit cell is defined to allow for the synthesis of functionally graded lattice structures.
Catholicism, Psychedelics, and Mysticism: Correlations and Displacements
Authors: Slatter Mark
Published: March 2024

This article charts some of the conversations around psychedelics, mysticism, Catholicism, and the Catholic mystics. I provide a context for the current “psychedelic renaissance” and bring the focus to psychedelics and Catholicism. The literature’s frequent comparisons of psychedelic mystical trips with Catholic mysticism raises questions about the legitimacy of religious ways of knowing, the status of the discipline of theology in Western academic cultures, and how Catholicism is often depicted in the psychedelic literature. The first part closes with a survey of the challenges of defining mysticism and some of the patterns perennial to the Catholic mystical experience. I look at the problem of methodological displacement, that is, how a researcher comes to conclusions with material that is formally outside of their discipline’s boundaries. This is a challenge for scholars of every stripe when they countenance subject matter that is beyond their expertise—and the lure to still read that material through their known methodology and worldview—but the problem of displacement is conspicuously compounded when the sciences countenance theological and religious themes. I provide concrete examples of displacement with psychedelic and Catholic mysticism, how it can be corrected, and how this would benefit dialogue. In the Conclusions, I outline persistent concerns and theological objections about some of the claims of psychedelic mysticism but hold onto the hope for further dialogue. My sustained attention is to the comparisons that are frequently made between the psychedelic and Catholic mystical experiences and whether these correlations are critically warranted.
Effects of Abelmoschus esculentus Extracts and Fractions on Embryos and Adult Individuals of Biomphalaria glabrata (Say, 1818) and on Schistosoma mansoni Cercariae
Authors: Leite João Claudio Vitoria Atico , Rangel Leonardo da Silva , Gomes Keyla Nunes Farias , de Albuquerque Ricardo Diego Duarte Galhardo , dos Santos José Augusto Albuquerque , Faria Robson Xavier
Published: March 2024

Schistosomiasis is a neglected tropical disease caused by parasitic worms of the genus Schistosoma. In Brazil, there are reports of infection by the Schistosoma mansoni species, which has the Biomphalaria glabrata snail as one of its intermediate hosts. The present work aimed to test the effects of different Abelmoschus esculentus seed extracts and fractions on adults and embryos of B. glabrata and S. mansoni cercariae. A total of four crude extracts and thirteen fractions with different organic solvents were used for the bioassays. The extracts were analyzed using high-performance liquid chromatography coupled to mass spectrometry. Molluscicidal activity was assessed in 24-well plates, after which the LC50 and LC90 were calculated. Assays with B. glabrata embryos and S. mansoni cercariae were also performed. These findings indicate the presence of flavanoids in the hexane, ethyl acetate, and ethanol crude extracts. For the molluscicidal activity assays, eight fractions had an LC90 value less than that recommended by the WHO. The methanol fraction of the dichloromethane extract (FrMeOH EDM) had the most promising results, with an LC90 of 37.15 mg/L and 100% mortality in embryos of B. glabrata and cercariae. FrMeOH, EDM, and other fractions are possible candidates for new drugs for the combat of schistosomiasis.
Dependence of Ships Turning at Port Turning Basins on Clearance under the Ship’s Keel
Authors: Paulauskas Vytautas , Paulauskas Donatas
Published: March 2024

Turning ships in port turning basins is an important and responsible operation, mainly involving the ship itself and the port tugboats. Such operations involve many maneuvers that consume a lot of energy (fuel) and emit a lot of emissions. Turning basins in harbors and quay approaches are, in most cases, relatively shallow. This paper examines the turning of ships in port turning basins using harbor tugboats, the effect of shallow depth on ship turning, energy (fuel) consumption and the generation of emissions during such maneuvers of harbor tugboats. This paper presents the developed theoretical models, and the experimental results on theoretical models that were verified on real ships and using calibrated simulators. Discussions and conclusions were prepared on the basis of the research results. The use of the developed methodology makes it possible to increase shipping safety, optimize maneuvers and reduce energy (fuel) consumption when turning ships in the port and, at the same time, reduce the amount of fuel consumed by port tugboats and reduce the number of emissions of tugboats during such operations.
The Impact of Carbon Emissions Trading on the Total Factor Productivity of China’s Electric Power Enterprises—An Empirical Analysis Based on the Differences-in-Differences Model
Authors: Chen Gezi , Hu Zhenhua , Xiang Shijin , Xu Ailan
Published: March 2024

Based on the panel data of China’s listed electric power enterprises, this paper adopts the differences-in-differences model to empirically analyze the pilot policy of carbon emissions trading’s impact on the total factor productivity of power enterprises in 2013. The study finds that the carbon trading pilot policy has a significant positive effect on the total factor productivity of power companies, and the two possible impact mechanisms are external cost compensation and additional income, and internal low-carbon technology innovation and resource allocation optimization. The conclusions above have been further confirmed by the parallel trend test and robustness test. The heterogeneity analysis demonstrates that there are differences in the regression results between state-owned enterprises and nonstate-owned enterprises. The possible reason is that state-owned enterprises are more likely to be affected by the carbon emissions trading system, and their asset-heavy model puts greater pressure on carbon emission reduction. Therefore, their demand for low-carbon technology innovation is more urgent; areas with stricter carbon emission verification are more sensitive to the implementation of carbon trading, and a reasonable increase in carbon verification can make the carbon trading market more effective. Based on the research results, this paper proposes to speed up the improvement of the national carbon trading market system, enhance the diversity and richness of the main market, improve the liquidity of the carbon trading market, broaden financing channels for electric power enterprises, and improve the carbon market supervision mechanism.
Dissemination of the Flavivirus Subgenomic Replicon Genome and Viral Proteins by Extracellular Vesicles
Authors: Ishikawa Tomohiro , Narita Kentaro , Matsuyama Kinichi , Masuda Michiaki
Published: March 2024

Extracellular vesicles (EVs) such as exosomes have been shown to play physiological roles in cell-to-cell communication by delivering various proteins and nucleic acids. In addition, several studies revealed that the EVs derived from the cells that are infected with certain viruses could transfer the full-length viral genomes, resulting in EVs-mediated virus propagation. However, the possibility cannot be excluded that the prepared EVs were contaminated with infectious viral particles. In this study, the cells that harbor subgenomic replicon derived from the Japanese encephalitis virus and dengue virus without producing any replication-competent viruses were employed as the EV donor. It was demonstrated that the EVs in the culture supernatants of those cells were able to transfer the replicon genome to other cells of various types. It was also shown that the EVs were incorporated by the recipient cells primarily through macropinocytosis after interaction with CD33 and Tim-1/Tim-4 on HeLa and K562 cells, respectively. Since the methods used in this study are free from contamination with infectious viral particles, it is unequivocally indicated that the flavivirus genome can be transferred by EVs from cell to cell, suggesting that this pathway, in addition to the classical receptor-mediated infection, may play some roles in the viral propagation and pathogenesis.
Advances in High-Performance Nanofiltration Membranes Facilitated by Two-Dimensional Materials
Authors: Xing Sichu , Du Songhang , Huang Yingyue , Qi Xingqi , Sui Minghao
Published: March 2024

Nanofiltration membranes (NF) have been widely used in the field of water treatment because of their advantages of high separation precision, easy operation, and no phase change. Conventional NF membranes, ensnared by the “trade-off” effect, grapple with the challenge of achieving breakthroughs in both separation efficacy and stability. Recent advancements in research have unveiled the potential of nanoscale porous two-dimensional (2D) materials, characterized by their atomic thinness and superlative mechanical strength. These materials, crafted into nanofiltration membranes as thin as a single atom, boast minimal transport resistance and maximal permeation flux, thereby facilitating the highly discerning transport of water, and are heralded as the quintessential materials for fabricating ultra-thin membranes. This comprehensive review delves into the latest advancements in the research on 2D material NF membranes. A range of performance aspects related to 2D-material-modified NF membranes, including water flux, permeability, pollutant retention rates, and anti-pollution performance, were evaluated, and this review covers the impact of and major approaches to optimizing membrane performance in recent years, providing valuable insights into potential future developments in NF membranes.
ANALISIS PENGARUH RASIO LIKUIDITAS DAN PROFITABILITAS TERHADAP PENGHINDARAN PAJAK
Authors: Fatikha Naeli , Furqon Imahda Khori
Published: March 2024

Wajib pajak yang melakukan upaya untuk menghindari pembayaran pajak dengan memanfaatkan celah hukum dalam peraturan perpajakan merupakan akibat dari perbedaan kebutuhan antara wajib pajak dengan pemerintah. Tujuan penelitian ini yaitu untuk mengetahui bagaimana rasio likuiditas dan profitabilitas mempengaruhi penghindaran pajak yang terdapat pada laporan keuangan tahunan yang dihasilkan oleh perusahaan Industri barang dan konsumsi subsektor farmasi di Bursa Efek Indonesia periode 2020–2023. Metode penelitian kuantitatif digunakan dalam penelitian ini dengan metode convenience sampling yang digunakan untuk menentukan sampel. Analisis regresi linier berganda merupakan metode analisis data yang digunakan dalam penelitian ini dengan bantuan program aplikasi SPSS versi 29. Temuan penelitian menunjukkan bahwa penghindaran pajak tidak dipengaruhi oleh rasio likuiditas. Namun, rasio profitabilitas mempengaruhi penghindaran pajak.
Análise multivariada aplicada para descrição do panorama educacional brasileiro
Authors: Soares Fernando Gualberto Silva , Silva Jackelya Araujo da
Published: March 2024

A proposta da Base Nacional Comum Curricular (BNCC) é estabelecer um conjunto de aprendizagens fundamentais que devem ser desenvolvidas por todos os estudantes, independentemente da região do país ou da rede de ensino em que estejam matriculados. Isso visa assegurar uma educação de qualidade, equitativa e que atenda às necessidades da sociedade contemporânea. É fundamental que as unidades de ensino do país, capitaneadas pelos seus gestores, tenham acesso a dados que possam ajudar a monitorar a aplicação da BNCC. Como são geradas muitas informações educacionais, uma análise univariada pode não ser o suficiente para descrever o panorama educacional e verificar a completude da execução das propostas apresentadas na BNCC. Dessa forma, o presente estudo tem por objetivo apresentar uma análise multivariada de grandes conjuntos de dados educacionais. No estudo a metodologia de agrupamento K−means possibilitou descrever que a taxa de evasão apresentou a menor variação para o ano de 2018. Ao mesmo tempo que o estado de Pernambuco apresentou maior taxa de média de horas aula para a rede pública de ensino. Evidenciou-se também que os ensinos da rede pública e privada possuem aspectos diferenciados. Exemplarmente, o ensino público no Estado do Ceará para o ano de 2022 apresentou similaridade ao ensino privado do Estado de São Paulo. A metodologia auxiliou na identificação das variáveis que contribuíram para que os grupos dos estados do Rio Grande do Norte, Pará e Bahia apresentassem alta dissimilaridade em relação aos demais estados da unidade federativa do Brasil.
Life path and scientific heritage of Professor Oleksii Kostyantinovych Bielousov (to the 175th anniversary of his birth and 115th anniversary of his death)
Authors: Sukhonosov R.O. , Semenenko O.V. , Shevtsov O.O. , Lopushnyak L.Y.
Published: March 2024

The article deals with the life of the outstanding scientist-anatomist, Doctor of Medicine, teacher, public figure and artist, Professor Oleksii Kostyantynovych Bielousov. He was born in 1848 into a family of noblemen in the family estate of Yuriyivka, Izyum district. In 1864, he entered the Law Faculty of Kharkiv University. Later, however, under the influence of the works of European and domestic physiologists, he turned to the study of natural sciences, began attending lectures on anatomy, and then finally moved to the medical faculty, which he successfully graduated from in 1875. At the end of 1875, Bielousov O.K. received a medical degree, in 1877 he became an assistant professor at the Department of Anatomy of Kharkiv Imperial University, and in 1899 he was appointed professor of the same department. From 1897 to 1908, Bielousov O.K. headed the Department of Anatomy and gave a course of lectures on normal anatomy at the School of Medicine of Kharkiv Imperial University. In his dissertation "Materials for the Anatomy of Human Vascular Nerves" (1889), Bielousov O.K. studied the peculiarities of the nerves' location in the walls of arteries and veins and described the data on vascular nerves for the first time. Both in lectures and in private conversations with students, Bielousov O.K. vividly and imaginatively characterized the multifaceted importance of anatomy for the development of the theory and practice of medicine, as well as physical culture, painting, and sculpture. Professors Vorobiov V.P. and Iosyfov G.M. became the most talented students of Professor Bielousov O.K. Professor Bielousov O.K. did a lot to expand the educational museum of the Department of Anatomy, which, thanks to his efforts, was enriched with many exclusive preparations, drawings and tables.

Keywords: Bielousov K.O., anatomy, history of medicine, biography.
HUBUNGAN VAKSINASI COVID-19 DENGAN TINGKAT KECEMASAN PADA LANSIA PASCA VAKSINASI DI PANTISOSIAL BUDI AGUNG KOTA KUPANG
Authors: Jahang Yohanes Christofel , Sasputra I Nyoman , Woda Rahel Rara
Published: March 2024

Prevalensi dan angka kematian selama pandemic corona virus disease 2019 (COVID-19) secara global maupun nasional semakin meningkat setiapharinya sehingga dilakukan berbagai intervensi untuk memutus penyebaran COVID-19 yang salah satunya adalah vaksinasi. Indonesia sendiri membagi bebera pake lompok penerima vaksinasi yang dilihat berdasarkan risiko tinggi terinfeksi COVID-19 salah satunya adalah kelompok lanjut usia (lansia). Berdasarkan hasil survey penerimaan vaksin bahwa terdapat 7,6% masyarakat menolak vaksin karena cemas dengan keamanan dan efektifitas dari vaksin ditambah lagi dengan adanya mutasi dari corona virus. Penelitian ini bertujuan untuk mengetahui apakah ada hubungan vaksinasi COVID-19 dengan tingkat kecemasan pada lansia pasca vaksinasi di Panti Sosial Budi Agung Kota Kupang. Penelitian ini menggunakan desain penelitian observasional analitik dengan rancangan cross sectional. Pengambilan sampel menggunakan teknik purposive sampling dan didapatkan 53 subjek penelitian. Dari hasil uji menggunakan uji chi-square, tidak terdapat hubungan antara vaksinasi COVID-19 dengan tingkat kecemasan lansia pasca vaksinasi dengan nilai p=0,071. Kesimpulan penelitian ini tidak terdapat hubungan antara vaksinasi COVID-19 dengantingkatkecemasanlansiapascavaksinasi di PantiSosial Budi Agung Kota Kupang.
HUBUNGAN TINGKAT STRES DENGAN KEJADIAN SINDROM DISPEPSIA PADA MAHASISWA PENDIDIKAN PROFESI DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS NUSA CENDANA KUPANG
Authors: Natu Deny Leonardo , Artawan I Made , Trisno Idawati
Published: March 2024

Dispepsia merupakan kumpulan gejala atau sindrom yang terdiri dari nyeri atau rasa tidak nyaman di bagian epigastrium, mual, muntah, kembung, cepat kenyang, rasa perut penuh, sendawa, regurgitasi, serta rasa panas yang menjalar di bagian dada. Salah satu faktor pencetus yang berhubungan dengan prevalensi kejadian dispepsia tersebut adalah faktor psikologis yaitu seperti stres, dimana saat stres terjadi maka tubuh akan merespon dengan disekresinya hormone kortisol. Tujuan penelitian untuk mengetahui hubungan antara tingkat stres dengan kejadian sindrom dispepsia pada mahasiswa Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Nusa Cendana Kupang. Metode  penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Teknik pengambilan sampel adalah stratified random sampling. Data diperoleh dari pengisian kuesioner DASS 42 dan PADYQ oleh 54 reponden mahasiswa Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Nusa Cendana Kupang yang memenuhi kriteria. Hasil analisis bivariat dilakukan dengan menggunakan uji statistik spearman’s rank correlation.Hasil penelitian dari data 54 responden menunjukan 34 responden (63,0%) mengalami stres dan 20 responden (37,0%) lainnya tidak mengalami stres (normal) dan untuk sindrom dispepsia data menunjukan 37 responden (68,5%) mengalami sindrom dispepsia dan 17 responden (31,5%) lainnya tidak mengalami sindrom dispepsia (normal). hasil uji statistik bivariat diperoleh hasil bahwa nilai p=0,03 yang menunjukan terdapat hubungan antara stres dan sindrom dispepsia pada mahasiswa Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Nusa Cendana Kupang. Kesimpulan penelitian terdapat hubungan yang signifikan antara tingkat stres dengan kejadian sindrom dispepsia pada mahasiswa Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Nusa Cendana Kupang yang menunjukan bahwa semakin tinggi mahasiswa mengalami stres maka semakin rentan mahasiswa mengalami sindrom dispepsia.
THE RELATIONSHIP OF DOCTORS AND PATIENTS IN A EDUCATIONAL HOSPITAL
Authors: Nurismail Eko Novanto , Corputty Dian Yelisa , Dewanti Intan Putri , Lada Christina Olly , Buntoro Ika Febianti Olly
Published: March 2024

The doctor-patient relationship, in this case communication, empathy and ways of serving patients, can be explored from an early age and continue to be developed and upheld by a doctor for successful therapy and in an effort to improve public health in the future within the teaching hospital environment. The purpose of this review article is to determine the importance of the doctor-patient relationship in a teaching hospital environment. This review uses 40 journals as sources in order to improve doctor-patient relationships in teaching hospitals. From this review it can be concluded that the main goal that young doctors are expected to achieve apart from medical science is soft skills in the form of how to create optimal therapeutic relationships with patients which can be practiced continuously during the professional education period at the Teaching Hospital.
HUBUNGAN TINGKAT DEPRESI DENGAN KUALITAS HIDUP PERAWAT RSUD PROF. DR. W Z JOHANNES DI ERA PANDEMI COVID-19
Authors: Matulessy Giovanni Kathlix immanuel , Buntoro Ika Febianti , Etty Dedy Maria Agnes
Published: March 2024

Latar Belakang : The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) telah meyebabkan wabah Coronavirus Disease (COVID19) yang mempegaruhi berbagai bidang di dunia, salah satunya bidang kesehatan. Perawat merupakan salah satu kelompok tenaga kesehatan yang memiliki proporsi jumlah terbesar dengan tingkat intesitas kerja yang tinggi di rumah sakit. Tingkat intensitas kerja yang tinggi, kesulitan menjalin hubungan dengan anggota keluarga, kesulitan dalam merawat pasien kritis, risiko terkena infeksi, dan faktor lainnya dapat menyebabkan ganguan psikologis seperti depresi bagi para perawat. Depresi pada perawat akan berdampak pada perubahan emosional, kognitif, motivasi, perasaan cemas, gelisah, perasaan terpuruk yang dapat menurunkan efektifitas kerja dan dapat mempegaruhi kualitas hidup perawat itu sendiri. Kualitas Hidup yang buruk memiliki  peranan penting untuk kesejahteraan dalam menjalani kehidupan dan akan berpegaruh pada masalah kesehatan sesorang yang mungkin timbul di kemudian hari.

Tujuan: Mengetahui hubungan antara tingkat depresi dengan tingkat kualitas hidup perawat pada era pandemi COVID-19 di RSUD Prof. Dr. W. Z. Johannes Kupang.

Metode : Penelitian ini merupakan penelitian analitikal observasional dengan rancangan cross sectional yang dilakukan pada perawat ruangan NICU,ICU dan komodo di RSUD Prof. Dr. W. Z. Johannes Kupang,dengan cara pengisian kuesioner Beck Depression Inventory II (BDI-II). dan kuisioner The World Health Organisasion Quaity Of Life (WHOQOL) –BREF. Teknik pengambilan sampel menggunakan Total sampling dengan jumlah responden 44 orang yang memenuhi kriteria inklusi dan eksklusi. Penelitian dianalisis secara univariat, bivariat menggunakan uji chi-square.

Hasil: Dari 44 responden, didapatkan hasil 29 responden (65,9%) tidak memiliki  depresi, 12 responden (27,27%) memiliki tingkat depresi ringan dan 3 responden (6,8%) memiliki tingkat depresi sedang. Dari 44 responden juga didapatkan 30 responden (68,18%) memiliki kualitas hidup buruk dan 14 responden (31,18%) memiliki kualitas hidup baik. Hasil uji analisis bivariat pada penelitiaan ini diperoleh hasil p=0,035 (p<0,05).

Kesimpulan : Terdapat  hubungan  yang  signifikan  antara  tingkat depresi dengan tingkat kualitas hidup perawat pada era pandemi COVID-19 di RSUD Prof. Dr. W. Z. Johannes Kupang.
TINJAUAN GEOGRAFIS DAMPAK PENGEMBANGAN EKOWISATA TERHADAP LINGKUNGAN HUTAN LINDUNG OELUAN DI DESA BIJELI KABUPATEN TIMOR TENGAH UTARA
Authors: Sanam Maria V. I. , Samin Mikael , Pamungkas Bella Theo Tomi
Published: March 2024

One of the tourism in Bijeli Village is the Oeluan Forest tourist area. The objectives of this study to: (1) describe the physical condition of the ecotourism development of the Oeluan Forest in the research area, (2) describe the impact of ecotourism development on the environment of the Oeluan Protected Forest in the research area, ; (3) describe the government's way of dealing with the degradation of the Oeluan Forest. The type of this research is descriptive qualitative with 20 informants, selected by purposive sampling. Sources of data in the form of primary data and secondary data. Data collection methods: interviews, observations, documentation studies. Qualitative descriptive data analysis. The results of the study are as follows: (1) the development of tourism in the Oeluan Forest Area in Bijeli Village continues to increase the tourism facilities and infrastructure such as villa accommodation and other supporting facilities and infrastructure. However, with this development there are several buildings that are not considered. (2) tourism development has an impact on the environment both on the community environment and the environment of the Oeluan Forest. The impact are lack of availability of clean water and damage to vegetation due to illegal logging and neglected development which can damage the Oeluan Forest and also scattered garbage. (3) the government needs to overcome forest degradation by reforestation and prohibiting people from carrying out forest degradation and cooperate  with the Bijeli community to carry out mutual cooperation.
Google Translate, ChatGPT or Google Bard AI: A Study toward Non-English Department College Students’ Preference and Translation Comparison
Authors: Hidayati Niswatin Nurul , Nihayah Dewi Hidayatun
Published: March 2024

The landscape of translation tools has evolved significantly, with an increasing reliance on artificial intelligence (AI) systems for various tasks. This study investigated the changing preferences among college students, especially those majoring outside of English departments, regarding the translation of abstracts from international journal articles. Besides, the authors also compared the translation results of Google Translate, ChatGPT and Google Bard AI. This research used qualitative research. The research results showed that the students prefer using AI such as ChatGPT or Google Bard AI. Moreover, whether the users used Google Translate, ChatGPT or Google Bard AI, the translation results showed that they were included in SL emphasis category.
Aplikasi Pencarian Tempat Pariwisata Berbasis Website (Studi Kasus: Provinsi Bengkulu)
Authors: Sapriadi Andri
Published: March 2024

Perkembangan teknologi informasi dan komunikasi ini bukan hanya memudahkan para wisatawan untuk dapat mengetahui tempat wisata yang ada saja tetapi juga dalam perencanaan pada saat liburan, seperti dalam pemesanan tiket perjalanan, penginapan dan tempat pemilihan wisata, bertransaksi dan lainnya. Dengan teknologi informasi dan komunikasi hal-hal tersebut akan sangat mudah dan cepat, wisatawan hanya dengan mengakses menggunakan gadget segera akan mendapatkan informasi yang dibutuhkan. penelitian ini akan berfokus pada bagaimana mengembangkan aplikasi sistem informasi pariwisata tekhusus pada objek penelitian dengan studi kasus pariwisata yang berada pada provinsi bengkulu. Pengembangan prototipe aplikasi sistem informasi pariwisata ini berdasarkan SDLC yang diusulkan dengan menggunakan metode-metode yang sudah jalankan, maka dapat disimpulkan bahwa aplikasi ini dapat digunakan dan dapat berjalan sesuai dengan yang diinginkan. Serta berdasarkan hasil blackbox testing didapatkan bahwa tidak adanya bug error yang ditemukan dari setiap fungsi yang ada pada aplikasi ini.
ANALYSIS OF CHATBOOT APPLICATIONS IN SERVICES OUTPUT TREATMENT WITH THE TAM MODEL APPROACH
Authors: Saputera Surya Ade , Afrika Sari Yuyun
Published: March 2024

Dalam pelayanan berobat jalan, terdapat keterbatasan sumber daya seperti tenaga medis, waktu tunggu, dan ruang fisik yang terbatas. Menggunakan aplikasi chatbot dapat membantu mengatasi keterbatasan dengan memberikan akses yang lebih cepat dan efisien bagi pasien untuk mendapatkan informasi dan konsultasi medis. Tujuan dari penelitian ini yakni untuk menganalisis persepsi pengguna terhadap penggunaan aplikasi chatbot dalam pelayanan berobat jalan menggunakan TAM Model. Metode penelitian dalam penelitian ini adalah metode survey, Populasi dalam penelitian ini adalah pasien yang melakukan rawat jalan. Metode analisis yang digunakan yaitu analisis regresi linier berganda, Uji –T dan Uji-F. Hasil penelitian Variabel Perceived Usefulness tidak berpengaruh terhadap Attitude Towards Using pengguna dalam penggunaan aplikasi chatboot dalam pelayanan berobat jalan dengan tingkat signifikansi 0,324 > α (0,05). Perceived Ease of Use berpengaruh terhadap Attitude Towards Using pengguna dalam penggunaan aplikasi chatboot dalam pelayanan berobat jalan dengan tingkat signifikansi 0,001 < α (0,05). Perceived Usefulness dan  Perceived Ease of Use secara bersama-sama berpengaruh terhadap Attitude Towards Using pengguna dalam penggunaan aplikasi chatboot dalam pelayanan berobat jalan.

Kata Kunci : Perceived Usefulness, Perceived Ease of Use, Attitude Towards Using, Chatbot, TAM Model
Pengembangan Protipe Aplikasi Sistem Informasi Berbasis Website Pada Salon Sabila
Authors: Putra Febriyanto
Published: March 2024

Penggunaan website sudah menjadi suatu perhatian oleh banyak kalangan, mulai dari pengusaha, akademisi, pemasaran, praktisi media masa, perusahaan, hingga instansi pemerintahan. Dari website ini banyak kalangan menggunakannya sebagai media promosi, alat, penjualan, hingga memberikan materi informasi yang berkaitan dengan gambaran detail suatu instansi atau Lembaga. Dengan adanya Teknologi Informasi Salon Sabila juga berkeinginan untuk menggunakan teknologi yang berkembang saat ini yaitu dengan memberikan pelayanan pada bidang jasa pemesanan dan pembayaran serta promosi pada Salon Sabila dapat dilakukan secara online. Pada penelitian ini berfokus pada prototipe aplikasi website yang dikembangkan untuk membantu menjalankan operasional salon sabila, dimana pada salon tersebut mempunyai sub usaha yang banyak seperti Penyewaan Alat-Alat Tata Rias Pengantin dan Video Shooting bergerak dibidang penyewaan alat-alat tata rias pengantin sekaligus wedding organizer dan video shooting. Untuk mendapatkan hasil dan analisis apakah prototipe ini dapat berjalan dengan baik, sesuai dengan alur penelitian yang telah dijelaskan pada bagian metode penelitian maka prototipe ini akan diuji menggunakan testing aplikasi, menggunakan blackbox testing. Berdasarkan hasil pengujian diatas dengan menguji beberapa input dan request system yang sedang dijalankan dapat berjalan sesuai dengan yang diharapkan, dan tidak menampilkan hasil error atau bug pada sistem prototipe tersebut. Maka dapat disimpulkan bahwa prototipe berhasil untuk dijalankan sesuai dengan harapan objek penelitian
Augmented Reality in Education: A Meta-Analysis Of (Quasi-) Experimental Studies to Investigate the Impact
Authors: Hunaepi Hunaepi , Sudiatmika A.A Istri Agung Rai , Fadly Wirawan
Published: March 2024

The objective of this study is to thoroughly examine the influence of AR on educational achievements by amalgamating findings from (quasi) experimental investigations. This study constitutes a meta-analysis approach, which involves analyzing previous research statistically. Specifically, it focuses on 15 articles meeting the determined criteria for data inclusion in this meta-analysis, encompassing: 1) Research Methodology: Restricted to studies carried out via experimental or quasi-experimental designs, 2) Pertinence to Research Variables: Emphasizing research directly investigating AR's impact on educational achievements, 3) Indexing: Inclusion of publications indexed by reputable databases like SINTA, DOAJ, Copernicus International, or Scopus. Statistical Measurements: Encompassing studies providing relevant statistical metrics ('r' and 't') concerning the relationship between the variables studied. The outcomes demonstrate that the evidence indicates a beneficial effect of AR in augmenting educational outcomes. This deduction is drawn from a considerable average estimated Effect Size (1.231) alongside an exceedingly low p-value (< 0.001), denoting a highly significant statistical association between AR and heightened educational achievements. Although the collective findings strongly support AR's advantageous impact on various educational aspects, further research is imperative to address acknowledged limitations and optimize the potential of AR technology in enhancing educational achievements, motivation, and engagement across diverse educational settings and student cohorts.
"Eventful": Revolutionizing Event Management through Technology Integration and User-Centered Design
Authors: Bello Adekunbi H.
Published: March 2024

The paper presents the development and analysis of "Eventful," an innovative event management system designed to streamline the planning process and enhance the connection between event organizers (customers) and service providers (vendors). By integrating technology advancements from the late 20th century to the present, including the internet, social media, cloud computing, and artificial intelligence, "Eventful" offers a comprehensive solution to the challenges of event management. The platform allows for direct communication, efficient vendor selection, and centralized planning, aiming to improve the overall efficiency and experience of organizing events. The research methodology includes qualitative interviews and surveys to identify user requirements and inform system design, ensuring that "Eventful" addresses the specific needs of its users effectively.
Effectiveness Of E-Backnshou Exercise To The Improvement Of Neck, Shoulder And Back Pain In Computer Vision Syndrome Patient
Authors: Julianti Hari Peni , Nugroho Trilaksana , Kesoema Tanti Ajoe , Susilaningsih Neni , Rahmi Fifin Luthfia , Pritadesya Maharani Prizka
Published: March 2024

BACKGROUND : Extra-ocular complaints of Computer Vision Syndrome (CVS) are neck, shoulder, back pain.  The 20-20-20 rule and E-BACKNSHOU exercise are expected to improve accommodative mechanisms, ocular surface of the eye and extra ocular symptoms of CVS.
AIMS :  Proving the effectiveness of E-BACKNSHOU exercise for the improvement of neck, shoulder and back pain in CVS patient.
METHOD : The research design was Pre-Post Test with Control Design. Subjects were 30 medical students of Faculty of Medicine, Diponegoro University, Semarang, Indonesia who experienced CVS and neck, shoulder and back pain. The treatment group got the 20-20-20 rule and E-BACKNSHOU exercise and the control group got the 20-20-20 rule for 1 month. Pain was measured by Visual Analogue Scale (VAS). Statistical test was conducted using paired t-test, unpaired t-test and chi square. Value of significance p<0.05.
RESULT :  There were significant differences in VAS score of neck, shoulder, upper back pain (p=0.00), and low back pain (p=0.022) before and after the intervention in the treatment group and VAS score of neck (p=0,002), shoulder (p=0.020), upper back (p=0.011), and low back pain (p=0.019) in the control group. Delta VAS score of the treatment group was greater than the control group and there was a significant difference in delta VAS score of shoulder pain (p=0,030), but there were no significant differences in delta VAS score of neck (p=0,934), upper back (p=0,356), and low back pain (p=0,150).
CONCLUSION : The effectiveness of 20-20-20 rule and E-BACKNSHOU exercise is better than the 20-20-20 rule alone on treating neck, shoulder and back pain in CVS patient.
Differences of Dyspareunia in Primipara with 2nd Degree Perineal Laceration Sutured with Rapide Polyglactin 910 and Chromic Catgut Threads
Authors: Wibowo Satrio Arief , Trisetiyono Yuli , Kristanto Herman , Wiyati Putri Sekar , Tjahjanto Hary , Erwinanto Erwinanto
Published: March 2024

BACKGROUND: Dyspareunia is persistent or recurrent pain during sexual intercourse. Perineal laceration, spontaneous or episiotomy, is one of the most common causes. Perineal lacerations that occur must be treated through suturing. Chromic catgut is a natural thread that is often used in medical practice, but this thread have a higher inflammatory response compared to Rapide Polyglactin 910.
AIMS: To analyze the difference in the incidence of dyspareunia in primipara with 2nd degree perineal lacerations sutured with Rapide Polyglactin 910 and Chromic catgut threads
METHOD: True experimental research with randomized controlled trial-single blinded method. The research was conducted at dr. Kariadi Semarang, RA Kartini Hospital and dr. Soeselo from August 2022 to February 2023. The research subjects were primipara with 2nd degree perineal lacerations which were divided into 2 groups, namely 45 subjects in the Chromic catgut group and 45 subjects in the Rapide Polyglactin 910 group. Evaluation of dyspareunia after 3 months was carried out using the Female Sexual Function Index (FSFI)
RESULT:  Subjects sutured using Chromic catgut had a 2.7 times greater risk of experiencing dyspareunia when compared to using Rapide Polyglactin 910 (OR=2.7; 95% CI=1.1-6.6). A significant confounding factor was found, namely the act of episiotomy (p=0.047; OR=9.56; 95% CI=1.86 - 48.97). After controlling for these variables, the subjects who were sewn using Chromic had a significant risk (p=0.002, OR=5.39; 95% CI=1.76-16.50)
CONCLUSION: Subjects with Chromic catgut have a higher risk of experiencing dyspareunia than using Rapide Polyglactin 910 threads after 3 months of suturing.
Characteristics and Risk Factor of Multidrug-Resistant-Organism Infection in the Pediatric Intensive Care Unit of Dr. Kariadi Hospital Semarang
Authors: Arkhaesi Nahwa , Supriatna Moh , Istanti Yusrina , Sari Desvita , Azzahra Safira Rizqi
Published: March 2024

BACKGROUND: The Pediatric Intensive Care Unit (PICU) that treats critical patients with various invasive procedures is a potential place for Multidrug Resistant Organism (MDRO) infections. This spesific unit, especially in tertiary care facilities may have higher prevalence of MDRO than non-PICU settings, causes serious disease and mortality. AIMS: To describe the characteristics and risk factor of MDRO infection in the PICU of dr. Kariadi Hospital Semarang, METHOD: Retrospective study in patients aged 1 month - 18 years with growth of germs on culture results during 2021-2022. Demographic data, use of central venous catheters and ventilator, length of stay, duration of antibiotic usage, and history of major surgery were investigated from medical records. The amount of risk expressed by the Odds Ratio (OR).RESULT: From 544 culture examinations, 199 (36.5%) germs grew, consisting of 79 MDRO isolates (39.7%) and 120 non-MDRO isolates (60.3%). Gram-negative bacteria were found in 140 samples (70.4%) with Klebsiella pneumoniae as the most common germ (15.1%) and respiratory tract infection (56.3%) being the most common infection diagnosis. As many as 24 of 30 (80%) isolates that grew Klebsiella pneumoniae were MDRO. Mechanical ventilator use (OR 2.15; 95% CI 1.07 – 4.3; p=0.043) and length of stay in the PICU (OR 2.44; 95% CI 1.21 – 4.96; p=0.018) are risk factors for MDRO infection.CONCLUSION: Klebsiella pneumoniae is the most common germ found from culture isolates and respiratory tract infection is the most common diagnosis. The use of mechanical ventilators and length of stay in the PICU are risk factors for MDRO infection.
PENAMBATAN SENYAWA ANTIVIRUS PADA RESEPTOR NON STRUCTURAL PROTEIN SEBAGAI AGEN TERAPETIK COVID-19
Authors: Amin Saeful , Rosmiyati Risna , Aprilia Ade Yeni , Adlina Salsabila , Prasetiyo Andri
Published: March 2024

COVID-19 is a disease that attacks the human respiratory system, until now there is no medicine specifically recommended to treat COVID-19, but infected people should still get appropriate treatment to overcome the symptoms of COVID-19. Nsp10 plays an important role in viral transcription. The study aimed to look at the binding value of affinity, hydrogen bonds, and amino acid residues between antiviral compounds and Nsp 10 receptors. The methods used in this study are the molecular docking method using AutodockTools 1.5.6 program, and visualization of docking results using Discovery Studio Visualizer. Antiviral compounds used favipavir, remdesivir, chloroquine, oseltamivir, hydroxychloroquine, ribavirin, umifenovir, lopinavir and ritonavir. The receptors used in this study were 7L6T receptors. The analysis of docking results showed that umifenovir compounds have the lowest binding affinity compared to other antiviral compounds against 7L6T receptors of -6.43 kcal/mol, predictable to have more stable interactions. So that the umifenovir compound can be used as a candidate for COVID-19 treatment.
ANEURISMAS CEREBRAIS: EMERGÊNCIA VASCULAR E ESTRATÉGIAS TERAPÊUTICAS
Authors: Conceição Humberto Novais da , Diogo Marina Pezzetti Sanchez , Maciel Lucas Santana e Silva , Ferreira Maria Eduarda Soubhia , Prehl Vinicius Barros , Chaves Nelson Silvestre Garcia , Resende Cristiane Daniela Gomes , Almeida Victor dos Santos Nogueira De , Melo Paula Paiva Castanheira , Junior Carlos Augusto Nunes , Castro Pedro Henrique Oliveira de , Dário Giovana , Barros Daniel Higor da Silva , Conceição Amado Dione Martins da , Guerra Luiz Guilherme Silveira
Published: March 2024

Introdução: Aneurismas cerebrais são dilatações anormais das artérias e, possuem risco de ruptura e hemorragia potencialmente fatal. Destaca-se a importância do diagnóstico precoce e tratamento eficaz para evitar complicações graves. Objetivos: O objetivo é compreender os aneurismas cerebrais, identificar fatores de risco, sintomas e complicações associadas, além de discutir as estratégias de diagnóstico e tratamento. Metodologia: Foi realizada uma revisão bibliográfica utilizando artigos disponíveis no PubMed. Os critérios de inclusão e exclusão foram definidos para selecionar estudos relevantes publicados entre 2020 e 2024. Resultados e Discussão: Os aneurismas intracranianos são classificados quanto à sua morfologia e podem ser identificados em várias artérias cerebrais. A hemorragia subaracnóidea resultante da ruptura de aneurismas causa sintomas graves e requer atenção médica imediata. A TC sem contraste é fundamental para o diagnóstico inicial, seguida por intervenções cirúrgicas como craniotomia e clipagem do aneurisma. O ressangramento e o vasoespasmo são complicações graves que exigem medidas terapêuticas urgentes para evitar danos neurológicos. Conclusão: O artigo destaca a complexidade e o potencial fatal dos aneurismas cerebrais, enfatizando a importância da rápida intervenção médica e da prevenção de complicações para otimizar os resultados clínicos.
TESTES E TRATAMENTOS DA TENOSSINOVITE DE QUERVAIN NA CLÍNICA ORTOPÉDICA DA REABILITAÇÃO FÍSICA: REVISÃO BIBLIOGRÁFICA SISTEMÁTICA
Authors: Lima Lucimar Candida de , Brandão Bruno Raphael Tadeu Moraes , Bezerra Cláudio Henrique Simão , Anderson Lucas Sena Santos , Neto Leonardo Kucko , Biallowons Salomon Schuster , Emerick Fernanda Teixeira , Rosa Octávio Lima Couto , Silva Eliana Marques Gomes da , Biallowons Lauren Lee Schuster , Aurélio Salete Martens , Cunha Ítalo Íris Boiba Rodrigues da
Published: March 2024

A Tenossinovite de Quervain (TQ), descrita inicialmente em 1895 pelo médico suíço Fitz de Quervain, é uma condição musculoesquelética dolorosa e crônica caracterizada pelo espessamento das bainhas tendinosas no primeiro compartimento dorsal da mão. O processo fisiopatológico se inicia com o comprometimento do primeiro compartimento dorsal do punho, onde estão localizados os tendões do ALP e do ECP. Desse modo, a problemática desse artigo é norteada com a seguinte situação problema: "qual é a eficácia dos tratamentos utilizados para Tenossinovite de Quervain (TQ) na capacidade funcional de pacientes acometidos por essa situação clínica ortopédica?". Objetivou-se, portanto, com esse artigo, analisar na literatura os impactos da Tenossinovite de Quervain na capacidade funcional dos pacientes afetados. Como resultados dessa revisão, foram encontrados 46 estudos, eliminaram-se os artigos duplicados, um total de 25. Após a leitura criteriosa dos títulos e resumos, foram selecionados 13 artigos, os quais estavam disponíveis na íntegra nas bases de dados, atenderam todos os critérios de inclusão e mostraram-se relevantes para o presente estudo. A revisão realizada destaca uma lacuna significativa na base de evidências científicas para os métodos conservadores no tratamento da TQ. A falta de estudos abrangentes e de alta qualidade deixa dúvidas sobre a eficácia desses métodos em comparação com as Injeções de Corticosteroides (ICs) e a Cirurgia.