bluuebunny/crossref_metadata_2025 huggingface dataset:
MELAYU PATTANI THAILAND: MUSLIM MINORITY RELIGION EXPRESSION IN THE MIDDLE OF NON MUSLIM MAJORITY
Authors: Arismunandar Arismunandar , Afriantoni Afriantoni , Asmuni Asmuni
Published: November 2019

Pattani Province in southern Thailand is the only province with the majority of the Muslim population. Besides Pattani the majority of Thai residents (67 million people) are Buddhists. Only 10% of Thai people are Muslims, including Pattani's Muslim Malay minority. Some data suggest that the Thai government made policies that often discredited and did not accommodate the interests of Malay Muslims. This became one of the reasons for the emergence of opposition to Thai government and ethnicity. For example, must use the Thai language (thaification Program) reinforced by the prohibition of the use of Malay language and nationalization of Thai society culture through language and customs. The cultural policies relating to the use of Thai language and customs are intended to promote Thai nationalism, while they erode the identity (religion and culture) of Pattani Malay. The Malay minority resistance was led by the scholar Tuan Guru Haji Sulong Al-Fathani. He also acted as negotiator with the Thai government in order to fight for Malay Muslim aspirations. His negotiations resulted in a policy of the enactment of Malay language education as a curriculum material at Pattani National School.
Uji Kadar Sari Larut Air Dan Kadar Sari Larut Etanol Daun Kumpai Mahung (Eupathorium inulifolium H.B.&K)
Authors: Febrianti Dwi Rizki , Mahrita Mahrita , Ariani Novia , Putra Aditya Maulana Perdana , Noorcahyati Noorcahyati
Published: December 2019

ABSTRAK Penentuan kadar sari larut air dan etanol adalah metode kuantitatif untuk jumlah kandungan senyawa dalam simplisia yang mampu tertarik oleh pelarut. Kedua cara yang hampir sama tersebut didasarkan ada kelarutan senyawa yang terkandung dalam simplisia. Secara turun temurun masyarakat dayak meratus dan dayak amandit menggunakan kumpai mahung (eupathorium inulifolium h.b.&k) sebagai obat diare dan malaria. Masih jarang penelitian menggunakan tanaman ini, sehingga peneliti bertujuan untuk mengetahui kadar sari larut air simplisia serbuk dan ekstrak daun kumpai mahung dengan metode yang telah ditetapkan oleh farmakope herbal. Hasil penelitian kadar sari larut air dan kadar sari larut etanol tanaman kumpai mahung pada serbuk memiliki nilai 19,54% dan 16,13%. Pada ekstrak memiliki nilai 19,53% dan 14,55%. Tumbuhan yang satu family yaitu asteraceae menyebutkan bahwa kadar sari larut air tidak kurang dari 5%, yang berarti hasil memenuhi persyaratan materia medika indonesia.Kata kunci: Sari Larut Air, Sari Larut Etanol, Kumpai Mahung, AsteraceaeABSTRACT Determination of water-soluble and ethanol extract contents is a quantitative method for the amount of compound content in a simplicia that can be attracted by the solvent. Both methods are almost the same based on the solubility of the compounds contained in simplicia. For generations, the Meratus and Amandit Dayak communities use kumpai mahung (Eupathorium inulifolium H.B. & K) as a medicine for diarrhea and malaria. Research is still rare to use this plant, so researchers aim to determine the content of water-soluble extract of simplicia powder and mahung kumpai leaf extract by the method established by herbal pharmacopoeia. The results of the research showed that the concentration of water-soluble extracts and ethanol soluble extracts of this plants on the powder had values of 19.54% and 16.13%. The extracts have values of 19.53% and 14.55%. One family plant, Asteraceae, states that the water-soluble extract content is not less than 5%, which means the results meet the requirements of Indonesian medical material.Keywords:  Water Soluble Extract, Ethanol Soluble Extract
Comparison of equivalent seismic load and response spectrum methods according to TSC 2018 and TSC 2007
Authors: Erkan İbrahim Hakkı , Doğan Talha Polat
Published: December 2019

In this study, two different analysis methods were compared; the first is a linear static analysis method and the second is a linear dynamic analysis method. First one is the Equivalent Seismic Load Method, which is a linear static method where seismic loads can be obtained by applying a simple calculation. The second method, the Response Spectrum method, is a linear dynamic analysis method which obtains the seismic loads using more complex statistical calculations. For this analysis study, 18 structural models with 3 different building heights were analyzed according to the conditions of Equivalent Seismic Load Method and Response Spectrum Method specified in both TSC 2007 and TSC 2018 and base shear forces obtained as a result of these analyzes were compared. As a result of analysis; compared to the results obtained from TSC 2007, due to the effective stiffness coefficients specified in TSC 2018, it was observed that the base shear forces obtained for both methods were lower and the modal period values were longer in the analyzes applied according to TSC 2018. This means that the structural systems created with the designs according to TSC 2018 are more ductile than the structural systems created with the designs made according to TSC 2007. Base shear forces obtained by 2 different analysis methods applied according to regulations stated in both TSC 2018 and TSC 2007; it was observed that the base shear forces obtained by the Equivalent Seismic Load Method were higher than the results of the Response Spectrum Method.
Modification of the effective area method on two-way loaded shallow foundations
Authors: Aytekin Mustafa
Published: December 2019

In rectangular/square based and two-way loaded (two-way eccentric) shallow foundations, four zones in which the resultant load might act are defined in the effective area method. Three out of the four zones that are employed in the determination of the effective areas overlap around kern. Only one zone that has a triangular-shaped effective area (called as case 1 in the literature) out of the four zones has no overlap with the others. The resultant load will always be out of the kern for case 1, and also it might be out of the kern for the remaining three cases. Design of foundations is not acceptable in general if the resultant load acts out of the kern. In the present study, the four cases are reconsidered. The zones on which the resultant load can be acting for the four cases are modified because these zones are overlapped partly. The modification has been made to have clear borders between the zones. On top of that, zone 4 is divided into two. A new zone corresponding to the area of kern is defined as zone 5. The design will be accepted if the resultant load acts within zone 5 (the kern). Also, the graphs in use to determine the dimensions of the effective areas are eliminated since it is not precise. Formulas are derived to determine the dimensions of the effective areas instead of using the graphs. Two new criteria are discovered and proposed to check whether the resultant load acts outside, inside or on the borderline of zone 5 (the kern).
Aritmômetros e seus usos no Brasil nos séculos XIX e XX
Authors: Silva Circe Mary Silva da
Published: December 2019

O presente texto discute sobre a circulação de ideias e artefatos pedagógicos entre diferentes países num processo de transferência cultural. Esta análise histórica utiliza a pesquisa documental com vistas à discutir sobre um material didático destinado ao ensino da aritmética - denominado contador- descrito no livro Arithmetica Elementar de Georg August Büchler, em 1919. Concluímos que este autor valeu-se de um livro didático para dialogar e justificar a importância de tal ferramenta no ensino do sistema decimal. Além disso, a formação de Büchler em escola normal germânica oportunizou conhecimentos de diversos materiais didáticos e permitiu uma apropriação deste conforme divulgado no livro didático Arithmetica Elementar.
World’s Leading National, Public, Monastery and Royal Library Directors: Leadership, Management, Future of Libraries by Patrick Lo, Allen Cho, and Dickson Chiu
Authors: Dozier Vanjury "V."
Published: December 2019

Lo, P., Cho, A., & Chiu, D. (2017). World’s leading national, public, monastery and royal library directors: Leadership, management, future of libraries. Berlin/Boston: De Gruyter. $114.99 (hardback), ISBN: 978-3-11-053083-4
Pembuatan Demplot Budidaya Tanaman Jagung Dalam Menambah Masa Tanam Di Lahan Kering Dengan Memanfaatkan Pupuk Organik
Authors: Widijanto Hery , Suntoro Suntoro
Published: November 2019

Program IbM ini bekerjasama dengan dua mitra, yaitu: (1) UKM Peternakan Puyuh “Agribird ”, dan (2) Kelompok Tani “Mekar Tani”. Mitra (1) dan Mitra (2) berlokasi di dukuh Gunung Wijil, Desa Ngringo, Kec. Jaten, Kab. Karanganyar, Jawa Tengah dengan jarak tempuh sekitar ± 3,5 km. Permasalahan utama yang dihadapi oleh mitra usaha „Agribird‟ adalah produksi limbah ternak puyuh yang sangat tinggi, yaitu sekitar 300 kg limbah per hari. Produksi limbahnya sangat tinggi per hari, maka kemampuan produksi limbah jauh melibihi dari kemampuan untuk memanfaatkannya. Bila limbah ini dibuang langsung ke badan sungai terdekat, maka akan mencemari air sungai, sedangkan bila limbah akan diubah menjadi pupuk organik, maka diperlukan teknologi pembuatan pupuk organik. Permasalahan Mitra 2 (Mekar Tani) : lahan yang tiap tahunnya ditanami padi selama 2 kali musim tanam. Musim tanam yang ke-3 diberokan (tidak ditanami), termasuk sawah-sawah petani yang ada di sekitarnya.Solusi yang ditawarkan untuk mengatasi permasalahan utama yang dihadapi mitra (1) adalah teknologi pembuatan pupuk organik yang dapat digunakan sebagai pupuk organik yang sangat bermutu yang dapat digunakan sebagai pupuk organik bagi usaha budidaya tanaman jagung pada mitra (2) yang dapat menambah masa tanam.Kegiatan ini merupakan penerapan Biofilmed Fertilizer yang telah diujikan pada penelitian Pengembangan Biofilmed Biofertilizer Beragens Hayati dari Konsorsia Rhizobiota Bawang Merah (RG Strategis Nasional 2015-2016) serta Teknologi Pengelolaan Limbah untuk Pakan dan Pupuk pada Sistem Pertanian Terpadu Berbasis Perikanan, Peternakan Puyuh dan Sayur Organik (RISTEK - Insinas 2014-2015).
Determinants of Capital Structure: Internal Factors (Accounting) versus External Factors (Market)
Authors: Rinofah Risal , Mumpuni Diah Lestari
Published: December 2019

This study aims to examine the role of internal and external factors on the capital structure and specifically will test which factors are dominantly affecting the company's capital structure. The results of this test can be subject to additional discussion on the capital structure both in the classroom and academic space in general because so far, the discussion of factors affecting capital structure is still focused on internal factors of the company alone, especially in Indonesia. This goal will be achieved by observing manufacturing company panel data for 10 years (2006 - 2015). Data will be tested using multiple regression analysis techniques, both with the Common Effect (OLS), Fixed Effect or Random Effect Models. The three models are used to accommodate variations in the characteristics of the sample of companies studied which generally will affect the relationship between variables. The test results show that the best estimation model is Fixed Effect with the finding that the Capital Structure is determined by internal (Accounting) and external (Market) factors, which are negatively affected by Liquidity (Current Ratio), Company Age (Age), and Stock Market Value (Mispricing). This result also shows that companies in Indonesia adhere to the Market timing Hypothesis and Pecking Order Theory in determining the capital structure theory.
Improving Service of Quality using Quality Function Deployment
Authors: Ekasari Ratna , Aziza Nurul , Prasnowo M Adhi , Hidayat Khoirul
Published: December 2019

AdiTeknik is one of the garages in Sidoarjo, East Java, Indonesia, engaged in repairing services industry tools. This garage recently has problems in attracting customers. Prior studies suggest that one of the things that affect the number of customers is customer satisfaction. After listening to complaints from several consumers, consumers said that they are less satisfied with the quality of the garage. This phenomenon become the trigger for us to investigate the customer satisfaction especially on the AdiTeknik garage. One method that can be used to help companies to improve the quality according to customer point of view is Quality Function Deployment (QFD). We find that there are twelve attributes of the desires and needs of consumers to improve the quality of garage service of AdiTeknik. Those are the quality of repair, cleanliness and neatness of the garage, complete facilities for customer, employee performance, repair results in accordance with demand, timeliness of completion, the ability to analyze problems, clarity fees and the completion time, warranty repair results, employee friendliness, ease of contacting a workshop, and a willingness to give feedback.
Special Issue on NIED Frontier Research on Science and Technology for Disaster Risk Reduction and Resilience 2019
Authors: Hayashi Haruo , Fukuyama Eiichi
Published: December 2019

The National Research Institute for Earth Science and Disaster Resilience (NIED) is working on three tasks: predicting disasters, preventing damage, and realizing speedy reconstruction and recovery efforts in the event of natural disasters such as earthquakes, tsunamis, volcanic eruptions, landslides, torrential rains, blizzards, and ice storms.

In the last three years of the NIED’s fourth mid/long term plan period, which began in 2016, natural disasters have occurred every year, including earthquake disasters such as the 2016 Kumamoto earthquake (M7.3) and the 2018 Iburi, Hokkaido, earthquake (M7.1). Disasters of the rainfall include the heavy rainfall in the northern Kyushu (Fukuoka and Oita) in July 2017, the heavy rain event in southwestern Japan in July 2018, the rainfall in northern Kyushu (Saga) in August 2019, and the heavy rainfall in Kanto and Tohoku in October 2019. There were also other disasters: an avalanche accident on Nasudake in 2017 and a phreatic eruption of Kusatsu-Shiranesan in 2018.

Due to the above-mentioned very frequent occurrence of such natural disasters on the Japanese islands, our institute has conducted several research projects to mitigate the damage from such disasters and to accelerate the recovery from them. As the third NIED special issue in the Journal of Disaster Research, several related research results were presented such as those on seismic disasters (Wakai et al., Nakazawa et al., and Ohsumi et al.), those on climatic disasters (Nakamura, and Ishizawa and Danjo), and those of their integrated researches for disaster risk reduction (Cui et al. and Nakajima et al.).

Although the achievements detailed in these papers are the results of individual research, the NIED hopes that these results as a whole will be fully utilized to promote science and technology for disaster risk reduction and resilience. The NIED hopes that this special issue awakens the readers’ interest in new research and, of course, creates an opportunity for further collaborative works with us.
Rainfall Indices at Estimated Occurrence Times of Sediment Disasters Triggered by the July 2018 Heavy Rainfall
Authors: Ishizawa Tomohiro ,   National Research Institute for Earth Science and Disaster Resilience (NIED) 3-1 Tennodai, Tsukuba, Ibaraki 305-0006, Japan, Danjo Toru
Published: December 2019

The July 2018 heavy rain, which was actually a series of intermittent downpours instead of a short-term continuous heavy rainfall, triggered a large number of sediment disasters. This study was conducted to evaluate sediment disaster triggers. In the study, an interview-based survey was conducted on the occurrence times of the sediment disasters caused by the heavy rain and a rainfall analysis was completed using analyzed rainfall data from the Japan Meteorological Agency. These were followed by an analysis of estimated occurrence times of the sediment disasters and the temporal changes in rainfall indices determined through the rainfall analysis. An analysis of disasters at 36 sites examined for the purposes of this study showed that many occurred when the soil water index (SWI) during the study period (June 28, 2018, to the estimated occurrence time of a sediment disaster) was maximized. The analysis also indicated that slope failures tended to occur when hourly rainfall was relatively low and the SWI was high and debris flows occurred when the SWI was high and hourly rainfall was relatively high. Examination of the data, considering the alert level of the SWI, showed that in cases where the SWI continued to increase after exceeding the alert level, 75% of the sediment disasters analyzed occurred within approximately 19 h.
Livelihood Re-Establishment of Emigrants from Kiribati in Fiji
Authors: Maekawa Miko , Singh Priyatma , Charan Dhrishna , Yoshioka Nagisa , Uakeia Takuia ,   The Ocean Policy Research Institute, Sasakawa Peace Foundation 1-15-16 Toranomon, Minato, Tokyo 105-8524, Japan,   School of Science & Technology, Department of Science, The University of Fiji, Lautoka, Fiji,   The University of the South Pacific, Kiribati Campus, Tarawa, Republic of Kiribati
Published: December 2019

People from Kiribati, especially after obtaining college degrees, tend to have a desire to migrate abroad to obtain further education and good jobs and, to some extent, due to the impacts of climate change. Nineteen percent of I-Kiribati migrants in Fiji who responded to our survey indicated climate change as a factor for their migration, but their primary reasons were to seek better education and employment. When seeking employment, their lack of English-language skills and professional qualifications posed challenges. However, those who had prepared well in advance tend to find jobs relatively smoothly after migration. When settling in a new area, people tended to rely on family connections, community groups, and other social supports as sources of network and safety net.
Influence of Religion, Culture and Education on Perception of Climate Change, and its Implications
Authors: Nakayama Mikiyasu , Taafaki Irene , Uakeia Takuia , Seru Jennifer , McKay Yolanda , Lajar Hermon ,   Graduate School of Frontier Sciences, The University of Tokyo 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8563, Japan,   Marshall Islands Campus, The University of the South Pacific, Majuro, Republic of the Marshall Islands,   Kiribati Campus, The University of the South Pacific, Tarawa, Republic of Kiribati,   College of the Marshall Islands, Majuro, Republic of the Marshall Islands
Published: December 2019

This study aims to quantitatively find the influence of religion, culture and education on the perception of climate change, and its implications. A survey was carried out, with students of a college and a university in the Republic of the Marshall Islands (RMI), and a university in Kiribati answering a questionnaire. It emerged that education has more influence than religion or culture on people’s perceptions of climate change and its implications, both in the RMI and Kiribati. It is interesting because the two countries are not homogeneous in terms of history, culture and religion. Another surprising finding was that seemingly contradictory ideas (e.g., no flooding in the future as stated in the Bible, compared with the perceived sea level rise) exist in the minds of the majority of the respondents, both in RMI and Kiribati. Having conflicting ideas in one’s mind may delay one taking action to cope with climate change and its implications.
Carnivalesque humour in Ça, c’est Filarmo, Nic
Authors: Novaković Nikola
Published: December 2019

The article analyses the humour in Hermann Huppen and Morphée’s series of comic books about a boy called Nick, with primary focus on the third issue, Ça, c’est Filarmo, Nic [That’s Filarmo, Nick]. Drawing on Bakhtin’s theory of the carnivalesque, the article identifies a variety of humorous devices, including wordplay, puns, quotations, unusual transformations, and mésalliances. Special attention is paid to the visual level of the comic book. Humour is located in visual metamorphoses, invisible “phantom” panels, and the incongruity between words and images. The article also addresses the comic book’s intertextual ties with Little Nemo in Slumberland, a series of comic strips from the early 20th century, and compares the way authority is represented and challenged in the two texts. The impossible spaces that Nick traverses within the chronotope of the road are examined as places that invert the usual hierarchies and relations, allowing Nick to experience a level of agency usually reserved for adults. The end of Nick’s travels across the dreamscape is examined as both a departure and continuation of the pattern from Little Nemo, and as a logical conclusion of a temporary carnivalesque subversion of traditional structures that dominate the adult world.
«Que en estos nuestros reinos llamábamos…»: a la búsqueda de una naturalización coeva de títulos y fórmulas de tratamiento en la traducción de la dramaturgia estuarda
Authors: Calvo García de Leonardo Juan José
Published: November 2019

Resumen. La traducción de textos no-contemporáneos, ‘diacrónicos’, se puede plantear desde la lealtad romántica al original hasta la absoluta domesticación. Centrándonos en la onomástica de los títulos heredados y adquiridos y en las fórmulas de tratamiento, proponemos una naturalización histórica y cultural, de modo que la reacción del público ante la puesta en escena de la traducción sea lo más equivalente posible a la del público de la cultura de partida, hoy en día.La parte teórica arranca con la presentación y explicación de lo que entendemos como tres modos básicos de traslación, junto con la argumentación de nuestra propuesta metodológica. A continuación, se expone una taxonomía de títulos heredados o adquiridos y de las fórmulas de tratamiento posibles en los textos originales y su tratamiento traductológico, según nuestras premisas.La parte práctica se inicia con una breve comparación de las versiones que cuatro traducciones canónicas, al alemán, el francés, el italiano y el español, dieron a dos títulos heredados o adquiridos en dos comedias, dos obras históricas y una ‘problem comedy’ shakesperianas. Pero nuestro corpus propiamente hablando consta de seis títulos heredados o adquiridos (Lord, Lady, Sir, Gentleman, Mr., Mrs.), veinte fórmulas de tratamiento de respeto, entre pares, incluyendo seis insultantes o degradantes (Your Grace, Lady, Your Ladyship, Your Worship, Worshipful, Right Worshipful, Right honourable, Sir, Fellow, Goodman/Goodwife, Master, Mistress, Madam, Miss, Rascal, Rogue, Sirrah, Wench, Hussy, Slut) y cuatro fórmulas paródicas o burlescas (Your Mastership, Your Solicitorship, His Wise Head, Reverend Ladies), extraídos de tres comedias ‘estuardas’ (Carlos I y Carlos II) del siglo XVII: A new way to pay old debts (1633) de Philip Massinger, The country wife (1675) de William Wycherley y Love for love (1695) de William Congreve.Palabras clave: onomástica, equivalencia histórica y cultural, traducción, naturalización, comedia del inglés moderno temprano
The Gumbel- Pareto Distribution: Theory and Applications
Authors: Et al. Saad
Published: December 2019

In this paper, for the first time we introduce a new four-parameter model called the Gumbel- Pareto distribution by using the T-X method. We obtain some of its mathematical properties. Some structural properties of the new distribution are studied. The method of maximum likelihood is used for estimating the model parameters. Numerical illustration and an application to a real data set are given to show the flexibility and potentiality of the new model.
Beneficial effects of melatonin in juvenile rats with heart failure
Authors: Wu Yao , Si Feifei , Luo Li , Jing Fengchuan , Jiang Kunfeng , Feng Siqi , Su Ya , Yi Qijian
Published: December 2019

Background: Adult rodent studies showed that melatonin is very effective in treatment of ameliorating cardiovascular disease. Melatonin is also able to reduce cardiac hypertrophy and heart failure (HF) in juvenile rodents. Here, we study the effect of melatonin on the cardiac function of juvenile rats with HF. Methods: Juvenile rats with HF were induced by abdominal aortic constriction (AAC). Sham-operated rats were established in parallel. Five weeks after the surgery, rats with ventricular dysfunction were randomly divided into two groups: the treatment group was injected with melatonin (10 mg/kg/d, intraperitoneal injection), and the HF group was injected with placebo. Simultaneously, placebo was administered to the sham group. Results: After administration for 4 weeks, the treated rats did not exhibit a decline in cardiac function as assessed by echocardiography analysis. Moreover, the increase in expression of ANP, BNP, caspase-1, IL-1β, bax, CaMKII, PLN, and RyR2 was markedly blunted by melatonin, while the decrease in expression of bcl-2 was improved in the melatonin treated rats. Conclusions: Our findings support a protective role of melatonin in cardiomyocytes, at least in part via reducing cardiac pyroptosis, apoptosis and remaining calcium homeostasis.
Exosome-shuttled miRNAs contribute to the modulation of the neuroinflammatory microglia phenotype by mesenchymal stem cells. Implication for amyotrophic lateral sclerosis
Authors: Giunti Debora , Marini Chiara , Parodi Benedetta , Usai Cesare , Milanese Marco , Bonanno Giambattista , Rosbo Nicole Kerlero de , Uccelli Antonio
Published: November 2019

Background Mesenchymal stromal/stem cells (MSCs) are characterized by neuroprotective, immunomodulatory, and neuroregenerative properties, which support their therapeutic potential for neurodegenerative diseases driven by microglia-associated inflammation, such as amyotrophic lateral sclerosis (ALS). One mode of action through which MSCs exert their immunomodulatory effects is the release of extracellular vesicles, including exosomes, that carry proteins, mRNAs, and microRNAs (miRNAs), which, once transferred, modify the function of target cells. We have investigated the role of miRNAs present in exosomes derived from IFN-γ-primed mouse MSCs in the modulation of microglia activation, and analysed their effect on target genes and signaling pathways. Methods We compared miRNA expression in IFN-γ-primed vs unprimed mouse MSCs by microarray and measured the levels of relevant miRNAs in their respective exosomes through RT-PCR. To assess the effect of dysregulated MSC-derived miRNAs, we transfected lipopolysaccharide-activated N9 microglial line cells and primary microglia from late-symptomatic SOD1G93A ALS mice with their specific mimics and analysed the mRNA expression of pro/anti-inflammatory genes in the cells. We used mirWalk and Panther and KEGG Pathway databases to predict target genes of specific miRNAs and possible pathways they regulate. Data were compared using Student’s t-test. Results We identified nine miRNAs that were significantly dysregulated in IFN-γ-primed MSCs, but present at different levels in their derived exosomes. Transfection with three of the four miRNAs significantly upregulated in IFN-γ-primed MSC-derived exosomes, namely miR-467f, miR-466q and miR-466m-5p, could modulate the pro-inflammatory phenotype of N9 microglia by downregulating Tnf and/or Il1b expression, and/or upregulating Cx3cr1 expression. We obtained similar results in primary microglia from SOD1G93A mice transfected with miR-467f and miR-466q. Further analysis of the mode of action of miR-467f and miR-466q indicated that they dampen the pro-inflammatory phenotype of microglia by modulating the p38 MAPK signaling pathway via inhibition of the expression of their target genes, Map3k8 and Mk2. Conclusion These results suggest that exosome-mediated transfer of functional miRNAs could be one mode of action through which MSCs exert their therapeutic effect in ALS by downregulating neuroinflammatory microglia, and identify miR-467f and miR-466q as immunomodulatory miRNAs involved in this process.
The development and process evaluation of the ACTION study: A person-centred communication intervention targeting nurse assistants in home care for older persons
Authors: Gustafsson Tanja , Sundler Annelie J , Lindberg Elisabeth , Karlsson Pernilla , Söderholm Hanna Maurin
Published: December 2019

Background A rapidly ageing population challenges the health care system in general and home care services in particular. Communication is a cornerstone of person-centred care. However, little research has been conducted on how to improve communication between health care professionals and older persons in home care contexts, despite research showing the importance of such interactions. The increasing demands on how to best and efficiently improve competence in health professionals is the reason why the ACTION intervention was conducted. This paper aims to describe the development and process evaluation of an educational intervention for nurse assistants (NAs) in home care and highlights the potential of self-directed web-based learning as well as the pitfalls of conducting complex interventions in home care. Methods A web-based educational intervention focusing on person-centred communication was developed that targeted NAs in home care for older persons. Twenty-seven NAs from two units in Sweden were recruited, and 23 NAs were offered the educational intervention. Data were collected from multiple sources before, during and after the intervention and were analysed using quantitative and qualitative methods. Data were extracted from the web platform and analysed to determine the NAs´ engagement in the intervention. Additionally, interviews, evaluation forms and field notes were used to evaluate the feasibility of the intervention. Results The main findings suggest that web-based education seems to be an appropriate strategy in the home care context. The majority of the NAs (91%) participated in full or in part in the intervention. During the implementation process, some adaptions were required to fit the local circumstances regarding technical support, scheduling, and the design of the lectures. The NAs perceived the format to be easy to use and flexible and appreciated the stepwise modules. The content was perceived as valuable. Conclusions Our findings show that the benefits of the web-based educational intervention included the short and focused lectures as well as its accessibility. Challenges with the implementation process included gaining access to the NAs and motivating and involving the NAs. This study emphasizes the environmental support needed to successfully conduct complex interventions, including physical, organizational and cultural aspects.
Oncolytic reovirus shows potentially anticancer effect against CT26 cell lines
Authors: babaei Abouzar , Soleimanjahi Hoorieh , Arefian Ehsan
Published: December 2019

Background: Reovirus type 3 Dearing (T3D) is a segmented double-stranded RNA that selectively replicates and triggers anticancer responses in the KRAS mutant cancer cells. Here, we examine the anticancer activity of ReoT3D against murine colon carcinoma cell line (CT26) with deferent in vitro experiments. Results: Our results showed that ReoT3D significantly induced oncolysis in the CT26 cells by induction of apoptosis, and cell cycle arrest in the G0/G1 and G2/M checkpoints and reduction of cell migration and colony forming ability. Conclusion: Present study confirmed that ReoT3D has strong anticancer impacts on CT26 cells which can be considered as a new approach against KRAS mutant cancer cell lines in laboratory investigation.
One Part Water, Two Parts Starch: Performing oobleck as political resistance
Authors: Widera Josh
Published: December 2019

Oobleck is two things: a non-Newtonian fluid, a mixture of cornstarch and water showing properties of both a liquid and a solid; and an invention by Dr. Seuss, an odd green weather occurrence who’s fluid, adhesive, and elastic attributes manage to threaten the entire state apparatus of the “Kingdom of Didd.” Re-viewing the children’s book Bartholomew and the Oobleck, and in light of its starch-and-water namesake, I argue that we can learn an insurrective strategy of political resistance from its performativity.
A Putative (Private) Life of Hannah Arendt: Bio-portraiture as performance in the work of Miriam Shenitzer
Authors: Zank Michael
Published: December 2019

The paper uses tropes culled from several of Hannah Arendt's works, as well as Rebecca Schneider's performance-theoretical considerations on "reenactment", to analyze the work of artist Miriam Shenitzer, specifically a show of drawings, captions, and objects called "A Putative Life of Hannah Arendt." The essay probes this "putative life" as construed from the artist's own memory fragments (including the memories of others that have become the artist's own), as well as from faux-artifacts that constitute a "collection" (à la Benjamin) without claim to representing an actual past. With access to history denied and a heritage claimed "without testament," the artist opens a space "between past and future," a moment of contemplation on the borders between private and public lives.
Teleworking: Decreasing Mobility or Increasing Tolerance of Commuting Distances?
Authors: Ravalet Emmanuel , Rérat Patrick
Published: December 2019

Teleworking is widely considered to be a way of solving mobility issues by decreasing the number of commuting trips. However, little is known about teleworking and, more specifically, its links with spatial mobilities and the potential rebound effects. Statistical analysis of data from
the Swiss Mobility and Transport Microcensus shows some limits to the ability of teleworking to regulate mobility in Switzerland. Firstly, commuting to a conventional workplace is replaced by (albeit shorter) journeys for other purposes. Secondly, and more importantly, teleworkers live further
away from the workplace than their colleagues (24.6 km vs. 16.1 km). Our analysis shows that, although teleworking may reduce the number of commuting trips, it is likely to increase the distance travelled over a working week. Being able to work at home for part of the week may consequently
decrease the propensity for residential relocation and increase tolerance for long distance commuting.
Determinación de la concentración letal media (cl50) producida por el sulfato de cobre pentahidratado en diez especies de peces dulceacuícolas bioindicadores utilizados en el Perú
Authors: Scotto Carlos , Rondón Raúl , Arriola César
Published: December 2019

El sulfato de cobre pentahidratado (CuSO4.5H2O) es utilizado en la acuicultura como un potente alguicida y/o molusquicida; pero el uso excesivo e indiscriminado puede conllevar a tener grandes daños en los cultivos de especies acuáticas silvestres no objetivo. La presente investigación determinó un rango de dosis letal media del sulfato de cobre entre 0.16 y 1.6 mg/L para diez especies de peces continentales: Neón Tetra (Paracheirodon Innesi), Dorado (Carassius auratus), Guppy (Poecilia reticulata), Bagre ventosa (Otocinclus macrospilus), Barbo (Barbus tetrazona), Molly (Poecilia sphenops), Monjita (Gymnocorymbus ternetzi), Espada (Xiphophorus helleri), Platy (Xiphophorus maculatus) y Corydora (Corydora aeneus). Para ello se realizó un ensayo preliminar de diez concentraciones seriadas por 24 horas con dos repeticiones. Seguidas de un ensayo final con cinco concentraciones seriadas a las 24, 48, 72, 96 y 120 horas de exposición. Posteriormente, se realizó el análisis con el programa Probit y se determinó que las CL50 fueron respectivamente de: 0,8mg/L,24h;1,2mg/L,96h; 0,4mg/L,96h; 1,2mg/L,48h; 0,8mg/L,48h; 0,16mg/L,24h; 0,8mg/L,24h; 0,1652mg/L,24h; 1,6mg/L,24h y 0,6mg/L,96h.
CARÁNGANO AND WOMEN: STORY OF AN INSTRUMENT THREATENED WITH EXTINCTION
Authors: Trujillo Andrea
Published: December 2019

This article describes the results of an ethnomusicological study on the carángano, a ground bow instrument played only by women in the small villages of the Colombia Caribbean region. Before the introduction of electricity, the inhabitants contemplated the full moon as the women played, danced and laughed to the sound of this instrument. This instrument is now almost extinct. In this article, the social function, organological structure and repertoire of this instrument are analysed. The relationship between the carángano and other ground bows such as the tingo-talango or the dumbu-kalinga and sekituleghe on the American and African continents is discussed. These musical practices require urgent attention since they harbour musical and identification values belonging to the Colombian Caribbean region while sharing cultural aspects which connect Africans and African descendants across vast distances.
Examining the quantity and quality of online sustainability disclosure within the Jordanian industrial sector: a test of GRI guidelines
Authors: Bani-Khalid Tareq
Published: November 2019

Reporting on corporate sustainability practices as being in congruence with social expectations is the core idea of legitimacy theory. Therefore, nowadays many organizations are making efforts to inform their stakeholders about the social, environmental and economic changes in their performance. Consistent with the argument above, this paper aims to examine the quantity and quality of corporate online sustainability information of the industrial sector in Jordan based on the Global Reporting Initiative guidelines. In line with content analysis method, this paper analyzes the quantitative sustainability indicators disclosed during last 7 years (2012–2018) by all the industrial sub-sectors listed on the website of Amman Stock Exchange. The results revealed that although all Jordanian industrial sub-sectors practice of the quantitative sustainability disclosure is in a modest degree in the period of 2012–2018, the emphasis on environmental and economic indicators was less than on social indicators in the corporate online reports. Results on qualitative analysis indicated that, considering all sustainability indicators, only the disclosure on indirect economic impacts, procurement practices, product responsibility, and economic performance have been reported at satisfactory levels of quality but with no compliance of GRI guidelines. According to the obtained results, policy makers in the Jordanian industrial sector should be very important players in order to open the channels of dialogue with corporate managers on the importance of their role in taking more responsibility for their non-financial operations. Consequently, this should ensure more transparent accountability through more quantitative and qualitative sustainability disclosure in the corporate reports.
Students’ Errors in Using the Simple Present Tense at Polytechnic ATI Padang
Authors: Indriani Silvia
Published: November 2019

The research aimed at analyzing the errors in using simple present tense at Logistics Management of Agro-Industry of Polytechnic ATI Padang. A qualitative method with descriptive approach was applied. The samples were 15% of 153 total students or 23 students. Data were collected through the writing test; namely, descriptive essay. The results show that many students commit errors in using the simple present tense. The errors are classified into four types: omission, addition, misinformation, and misordering. There are 107 errors with the highest number that is omission (61 errors or 57%). Misinformation is in second place with 29 errors (27,1%). The error of addition gains 11,2 % with 12 errors. The lowest error is misordering, which gains 4,7% with only five errors. In conclusion, the most dominant error made by the students is omission with 57% and misordering is the lowest one with 4,7%. Therefore, the lecturers are expected to improve the teaching strategies in teaching simple present tense to reduce the numbers of students’ errors.
Ischemic stroke and antithrombotic therapy: key aspects
Authors: Maksimova M. Yu. , Fonyakin A. V. , Geraskina L. A.
Published: December 2019

The paper considers the key areas of antithrombotic therapy for ischemic stroke (IS). Antiplatelet therapy is shown to be a multistage and multidisciplinary strategy of treatment for patients with IS, which begins with the appearance of the first symptoms of the disease and continues throughout life. Each stage, including fibrinolytic therapy, early use of antithrombotic and anticoagulant drugs, and personalized antithrombotic prevention of recurrent cerebral disorders, is important in itself and serves a common goal. As a result, all efforts should be aimed at reducing mortality rates in the acute phase of stroke and the functional dependence of a patient and at preventing venous thromboses, recurrent stroke, and all cardiovascular events to increase life expectancy and to improve quality of life. Fibrinolytic therapy increases the patient’s chances of a full neurologic recovery and improves the quality of later life. Antithrombotic drugs reduce the risk of cardiovascular death, early recurrences of stroke, and recurrent noncardioembolic stroke. Parenteral anticoagulants in acute stroke decrease the risk of venous thrombosis/thromboembolism, oral anticoagulants reduce that of recurrent cardioembolic stroke.
A contemporary view of the possibilities of preventing dementia
Authors: Bogolepova A. N.
Published: December 2019

The prevalence of dementia increases progressively, which actualizes the issue of prevention. Primary prevention of dementia involves preventing the transformation of mild cognitive impairment (MCI) into dementia, secondary prevention involves the early detection and early treatment of dementia, and tertiary prevention involves slowing down the progression of dementia. Current studies pay much attention to the correction of modifiable risk factors due to lifestyle, as primary prevention. Physical activity is a very important component of a healthy lifestyle, which is aimed at preventing the development of cognitive decline. The mechanisms of the positive effect of physical activity on cognitive functions are associated with decreased risk of cardiovascular disease, increased cerebral perfusion and cerebral blood flow, changes in neurogenesis and neuronal plasticity. Nutrition strategies focus on dieting, among which the Mediterranean diet has produced hopeful results. Sleep normalization is also considered a very important aspect of the prevention of cognitive impairment, because sleep disturbances provoke the development of cardiovascular pathology and affect the amyloid metabolism. However, along with combating risk factors, more and more attention is now being paid to the possibilities of drug treatments to prevent dementia. The experimental studies confirmed the neuroprotective effect of Akatinol (memantine). The clinical studies proved the efficacy of Akatinol in the treatment of Alzheimer’s disease and vascular dementia and showed the disease-modifying effect.
Analisis Permasalahan Guru dan Siswa Menggunakan Pembelajaran Berbasis Masalah dengan Media LCD (Liquid Crystal Display) Terhadap Hasil Belajar IPA Biologi
Authors: Faridah Faridah , Maasawet Elsje Theodora , Boleng Didimus Tanah
Published: December 2019

The function of education is to prepare students through a process that takes place before students are ready to work in real life. The strategy for implementing education is carried out in the form of guidance, teaching and training activities. In line with that  national education must be able to guarantee equal opportunities for education, improvement in quality, and efficiency of education management. Improving the quality of education is directed at improving the quality of Indonesian people as a whole through cognitive, affective aspects, and psychomotor aspects. The purpose of the study was to determine the problems of teachers and students in the problem-based learning model with the use of Liquid Crystal Display Media on the results of Biology Science. The design of this study uses quasi experimental. Based on observations and interviews with Biology Science teachers that students tend to remain silent in class, pay less attention to teachers, play with their peers so that the average cognitive learning value results are 63.50%. Based on the results of interviews with students, information was obtained that the teacher had been giving a woman a monotonous method, namely lecture and lack of interaction with students so that some students felt they did not understand the material.
Karakterisasi Morfologi Anggrek (Orchidaceae) di Hutan Kecamatan Ngaliyan Semarang
Authors: Shidiqy Hasby Ash , Wahidah Baiq Farhatul , Hayati Nur
Published: December 2019

Orchid is one ofthe flowering plants with a very high level of diversity, including the diversity of morphological characters it has. This study aims to determine the diversity of orchids (orchidaceae) seen morphologically in the Ngalian sub-district forest in Semarang city. The method used in this study is cruise method and characterization techniques. Analysis of research data was carried out descriptively and displayed in the form of tables and photos. Orchids in the teak forest cover 940 ha, spread in 4 villages, namely Wonosari village, Gondoriyo village, Podorejo village and Wates village. The results showed that there were 3 types of orchid plants (orchidaceae). The types of orchids include Rhynchostylis retusa (L.) Bi., Rhynchostylis gigantea (Lindl.) Rindl. and Dendrobium crumenatum (L.) Sw. The diversity of morphological characters in each species of orchid such as diversity in leaf color, leafshape, leaftip shape, stem color, root type etc.
Análisis factorial para la validación de las variables en un modelo de alianzas estratégicas en microempresas mexicanas
Authors: Mora Castellanos Consuelo , Cano Olivos Patricia , Martínez Flores José Luis , Sánchez Partida Diana
Published: December 2019

Introducción: El objetivo de esta investigación es validar las variables que son consideradas en un Modelo Conceptual de Alianzas Estratégicas para Microempresas Comercializadoras. Para tal efecto, se utiliza el análisis factorial exploratorio.Método: Para el estudio se recolectaron datos a través de una encuesta, la cual se aplicó a 204 microempresas comercializadoras, ubicadas en Hermosillo, Sonora. Los datos fueron analizados mediante el programa de software SPSS versión 23.0Resultados: Los resultados muestran que el instrumento utilizado para la recolección de datos es aceptable, pues se tiene un valor de alfa de Cronbach de 0.855. Por otro lado, con el análisis factorial se hizo evidente que las variables a considerar en el Modelo Conceptual de Alianzas Estratégicas para Microempresas Comercializadoras son las correctas, y se agruparon por factores.Discusión o Conclusión: Las microempresas pueden formar parte de una red de alianzas vinculadas a empresas más grandes. Por la simplicidad del Modelo Conceptual de Alianzas Estratégicas para Microempresas Comercializadoras, los empresarios pueden utilizar este modelo como guía para generar ventajas competitivas.