bluuebunny/crossref_metadata_2025 huggingface dataset:
Technology Use for Home-Based Stroke Rehabilitation in Switzerland From the Perspectives of Persons Living With Stroke, Informal Caregivers, and Therapists: Qualitative Interview and Focus Group Study (Preprint)
Authors: Sauerzopf Lena , Luft Andreas , Maeusli Valeria , Klamroth-Marganska Verena , Sy Michael , Spiess Martina Rebekka
Published: July 2024

BACKGROUND

Stroke is a leading cause for long-term disability, requiring both inpatient and outpatient rehabilitation and self-training in the home environment. Technology-based tools are gradually gaining acceptance as additional and suitable options for extending the rehabilitation process. While the experiences of persons living with stroke, therapists, and informal caregivers with respect to technology use have already been investigated in other countries, this topic is underexplored in the Swiss context.

OBJECTIVE

We aimed to explore the experiences and needs of persons living with stroke, informal caregivers, and therapists in using technology-based tools in a home environment for stroke rehabilitation in Switzerland.

METHODS

This study followed a qualitative descriptive methodology, including semistructured interviews and focus group discussions. We applied a deductive template analysis alongside the accessibility, adaptability, accountability, and engagement framework to analyze the qualitative data sets for technology-assisted solutions for poststroke rehabilitation.

RESULTS

We collected the experiences and needs of persons living with stroke (7/23, 30%), informal caregivers (4/23, 17%), and therapists (occupational and physical therapists; 12/23, 52%). The 4 categories we used to organize the analysis and results were accessibility to quality rehabilitation, adaptability to patient differences, accountability or compliance with rehabilitation, and engagement with rehabilitation. Persons living with stroke stated that they use various tools within their rehabilitation process depending on their specific needs. They felt that there is a plethora of tools available but sometimes felt overwhelmed with the selection process. Informal caregivers indicated that they generally felt underserved and insufficiently informed throughout the rehabilitation process. They reported that they use technology-based tools to support their relatives affected by stroke in becoming more independent. Therapists appreciate the numerous possible applications of technology-based tools in rehabilitation. At the same time, however, they express dissatisfaction with the lack of clarity in Switzerland regarding cost coverage, recommendations, and training opportunities.

CONCLUSIONS

Persons living with stroke, informal caregivers, and therapists in Switzerland reported varied and unique experiences and needs with the use of technology-based tools in outpatient stroke rehabilitation. Written recommendations, the assumption of financial costs, and the provision of information and education could foster increased confidence in the use of technology-based tools for patients and therapists.
"Development and Implementation of a Personal Virtual Assistant for Patient Engagement and Communication in Post-Surgical Cancer Care: A Feasibility Study" (Preprint)
Authors: Bargas-Ochoa Miguel , Zulbaran-Rojas Alejandro , Finco M.G , Costales Anthony B. , Flores-Camargo Areli , Bara Rasha O. , Pacheco Manuel , Phan Tina , Khichi Aleena , Najafi Bijan
Published: July 2024

BACKGROUND

Cancer care complexity heightens communication challenges between healthcare providers and patients, impacting their treatment adherence. This is especially evident upon hospital discharge in patients undergoing surgical procedures. Digital health tools offer potential solutions to address communication challenges seen in current discharge protocols.

OBJECTIVE

We aim to evaluate the usability and acceptability of an interactive health platform among discharged patients who underwent oncology-related procedures

METHODS

A four-week observational study was conducted. Following hospital discharge, a tablet equipped with an integrated Personal Virtual Assistant (PVA) system was provided to patients who underwent oncology-related procedures. The PVA encompasses automated features that provide personalized care plans, developed through collaboration among clinicians, researchers, and engineers from various disciplines. These plans include guidance on daily specific assignments that were divided into 4 categories: medication intake, exercise, symptom surveys, and post-procedural specific tasks. The primary aim assessed the feasibility of the PVA by quantification of dropout rate <10%, and adherence to each care plan category throughout the study duration. The secondary aim assessed acceptability of the PVA via a Technology Acceptance Model (TAM) questionnaire that examined ease of use, usefulness, attitude towards use, and privacy concerns.

RESULTS

Seventeen patients were enrolled. However, 1/17 (5.8%) patients dropped out from the study after 3 days due to health deterioration, leaving 16/17 (94.2%) completing the study (54.5±12.7 years old, 52% Caucasian, 82% gynecological disease, 18% hepatobiliary disease). At the study endpoint, adherence to care plan categories were: 78% for medications, 81% for exercises, 61% for surveys, and 58% for tasks. There was an 80% patient endorsement (strongly agree + agree/very easy + easy) across all TAM categories.

CONCLUSIONS

The PVA is a feasible and acceptable tool for discharged patients undergoing oncology-related procedures, showing reproducibility for a future clinical study assessing effectiveness.
United Nations Roundtable on Telemedicine: Lessons Learned and Differing Perspectives (Preprint)
Authors: Azzolini Claudio , Boscher Claude , Capone Jr Antonio , Donati Simone , Falco Andrea , Oggionni Francesco , Loewenstein Anat , Paolucci Umberto
Published: July 2024

UNSTRUCTURED

Invited panelists from different countries, who are actively involved in digital medicine, discussed the current state and future prospects of telemedicine at a roundtable during an international conference. The discussion covered various aspects of telemedicine, including the available technologies, the critical need for comprehensive databases, and insights on completed projects and their long-term viability. Our expertise in technology, telemedicine projects, and sustainability can be valuable, with the understanding that the ideas expressed can be applied to other fields and situations. The overall aim is to leverage experience to support the successful implementation of new telemedicine projects across different healthcare sectors.
Randomized e-Hypnotherapy for Chronic Pelvic Pain Study (REST): Comparing e-Hypnotherapy to Relaxation and Waitlist to Improve Pain, Cost Effectiveness and Biopsychosocial Outcomes (Preprint)
Authors: Evans Subhadra , Naude Colette , Coitinho Biurra Yao , Bowring Jessica , Knowles Simon R. , Brooks Tiffany , Skvarc David , Esterman Adrian , Fuller-Tyszkiewicz Matthew , Klas Anna , van Niekerk Leesa , McCaffery Nikki , Stanley Katherine , Druitt Marilla , Andrews Jane , Vancaillie Thierry , Cheah Suiyin , Ciccia Donna , Blake Lily , Bassili Anna , Mikocka-Walus Antonina
Published: July 2024

BACKGROUND

Background: Chronic pelvic pain (CPP), defined as persistent pain in the structures of the pelvis, is a condition that significantly impacts the health-related quality of life (HRQoL) of up to one-third of people worldwide, with substantial associated costs to both the individual and healthcare system/s.

OBJECTIVE

The present trial aims to establish the efficacy of e-hypnotherapy over relaxation and waitlist controls on pain, HRQoL, and biopsychosocial outcomes, and to evaluate cost-effectiveness.

METHODS

Methods: A parallel-group, investigator-blinded, randomized control trial will be conducted. Eligible participants will be randomly allocated to either a 7-week online personalized e-hypnotherapy program (n = 44), a 7-week online personalized relaxation control (n = 44), or waitlist control (n = 44). The primary outcome will be self-reported pain level and secondary outcomes will include psychological distress, QoL, pain catastrophizing, self-efficacy, central sensitization, somatic symptoms, fatigue, and sleep. Cost-effectiveness will also be examined. Longitudinal qualitative interviews will be conducted with participants in the e-hypnotherapy (n = 20) and relaxation (n = 20) groups, to understand barriers/facilitators for ongoing use.

RESULTS

Data analyses will include mixed-effects regression models, cost-utility analysis from a health system and societal perspective, and thematic analysis. The e-hypnotherapy program will also be reviewed by a group of eligible healthcare providers who will consider potential barriers/facilitators for ‘real world’ implementation.

CONCLUSIONS

n/a

CLINICALTRIAL

This protocol has received ethics approval in Australia from Deakin University Research Ethics Committee (DUREC Ref.2024-080). The trial was prospectively registered in the Australian New Zealand Clinical Trials Registry on 13th April 2023 (ID: ACTRN12623000368639).
Feasibility ,User Acceptance and Outcomes of Utilizing a Cancer Prehabilitation App for Exercise: A Pilot Study (Preprint)
Authors: Zhang Fuquan , Bang Deepali , Visperas Christine Alejandro , Mon Hnin Tun , Tay San San
Published: July 2024

BACKGROUND

The efficacy of cancer prehabilitation programs is supported by international reviews and meta-analyses. Technology has been deployed in cancer prehabilitation to address challenges such as access or limited resources. This study evaluated the feasibility, user acceptance, safety, and program outcomes of a newly developed mobile application for cancer prehabilitation. The app integrates with Singapore's existing healthcare mobile app, Health Buddy, and provides instructional videos for prescribed exercises.

OBJECTIVE

The objectives of this study were to investigate the feasibility, user experience, safety, and outcomes of a mobile app for cancer prehabilitation within a hospital-associated home-based multimodal cancer prehabilitation program.

METHODS

This was a retrospective analysis involving patients enrolled in the Cancer Prehabilitation program from September 1st, 2022, to March 30th, 2023. Patients enrolled in the prehabilitation program (n=66) were categorized into two groups: those prescribed the app (n=43) and those who were not (n=23). There was further subgroup analysis of those who were prescribed: app-users (n=25) versus those who were not (n=18). Demographics, Fried Frailty Phenotype, prehabilitation duration, app use, compliance to the program and functional outcome measures (6MWT, STS, TUGT, HADS) were collected. Baseline characteristics and pre-operative outcomes were compared between the groups. User satisfaction was assessed through surveys among app users (n=25).

RESULTS

Among 66 patients, 43 (65%) were prescribed the app of which 25 (58.1%) were users. No significant differences in pre-operative functional improvements were observed between app users and non-users, or between those prescribed and not prescribed the app. However, high compliance rates (80%) were observed among app users. Patient satisfaction with the app was high (>90%), with positive feedback on ease of use and technical reliability . Baseline measures revealed significantly lower functional scores and higher mean frailty scores in the non-prescribed group.

CONCLUSIONS

This preliminary study demonstrates the acceptability, feasibility and safety of Singapore's first smartphone app for exercise prescription in cancer prehabilitation. Lower baseline functional outcome measures and a higher mean frailty score in the unprescribed group has implications in the selection process and patient participation. Further studies should include strategies to enhance patients’ readiness for technology, sustainability as well as effectiveness in older patients.
Approaching a National Film History through Data. Network Analysis in German Film History
Authors: Hagener Malte , Blaschke Theresa
Published: July 2024

The present paper is an attempt at importing network analysis as a method and applying it to a field that has hitherto been examined in different ways: the study of national cinema. The approach was motivated by the perceived conundrum in the existing studies of German cinema that filmhistorical and political history usually do not match. The aim is to open up another perspective on the problem of periodization by looking at the data of film production, more specifically of collaboration. By using a comprehensive data set which is made availavable by the Filmportal, the central internet platform on German film, the approach in this paper is to look at the key creatives involved in the production of a film in the period from 1919 to 1939 and to conceptualize collaboration and connectivity in a (national) film culture through the use of network research methods.
Business in the 2020s—Between Theory and Practice
Authors: Avny Amos
Published: July 2024

The article discusses how Business, in general, should proceed between economic theory and the daily practice of the 21st century’s chaotic conditions. It has, first, to realize that this is the situation, secondly, both, economists and business men and women, should prepare and get themselves ready to act within this convoluted reality. The author follows G, Shaw’s idea on “unreasonable men that bring progress” divides normal societies into similar two population groups; the majority–the Squares and the minority-the Stars. Further, the Author checks several economic undertakings and tries to understand what is the proper mix or mission for them. Further, the Author claims, while resting on the historical neglected Emotional Intelligence’ teaching, that the form and the nature of future activities should change. They should be more people-oriented, more opened-minds and more creative, resourceful and flexible. The Author inquires ten major economic indicators and find out that both the traditional Capitalism and Socialism movements lost their relevancy at present. Thus, time comes to launch new sets of rules and regulations for, assisting people and organizations in their struggle to survive, prosper and flourish. In sum, the Author foresees that in the future, in parallel to the technological advancement, or together with it, public or private organizations and individuals, would be required to act and be more sensitive and more attuned to the individuals, communities and the universe’s demands.
Seismic Analysis of Re-Entrant Corner Plan Irregular Buildings with Roof Openings Using STAAD Pro: A Case Study for Zone III Earthquake Intensity
Authors: Mayda Sanjay
Published: July 2024

Abstract: This research investigates the possibility of including roof openings in the re-entrant corner plan irregular buildings at different positions for the response to seismic loads. Five different models with different types and levels of diaphragm discontinuity were analyzed using the STAAD Pro software. Variables such as node displacement, storey shear X and Z directions, stress, and maximum bending moment were investigated to measure the efficiency of the structure. The findings reveal that models featuring heightened diaphragm discontinuity tend to exhibit amplified node displacements, storey shear, and stress levels. Particularly, Model M3, showcasing a 17% diaphragm discontinuity, consistently demonstrates superior performance by showcasing reduced displacements and stress values compared to its counterparts. However, it's imperative to note that the ultimate selection ofthe model should be contingent upon specific project requisites and design considerations. In essence, the study underscores the importance of considering the impact of roof openings and diaphragm discontinuity on the structural behavior of re-entrant corner plan irregular buildings under seismic loads. While Model M3 emerges as a promising candidate for its favorable performance metrics, the holistic evaluation should encompass project-specific factors to ensure an optimal structural solution. This research underscores the significance of comprehensively evaluating structural performance in irregular buildings with roof openings. While Model M3 exhibits notable advantages, including reduced displacements and stress levels, the complexity of real-world projects necessitates a nuanced approach, considering factors beyond purely numerical analysis, such as architectural constraints and functional requirements.
Evaluation of the Long-Term Strength of Concrete in Building Structures
Authors: Putlyaev V. I. , Berlinova M. N.
Published: July 2024

An approach to estimating the long-term strength of concrete in building structures in the calculation of reinforced concrete structures of buildings and structures of various types is proposed. The process of increasing the initial modulus of concrete deformations in time as a consequence of a certain physicochemical reaction of strength gain is considered. The function of the age of concrete is presented, taking into account the change in the modes of temperature effects during the period of hardening. It is shown that the entropy criterion of strength is more flexible compared to the criterion of the energy barrier of destruction. The application of the entropy strength criterion allows us to take into account the effect of temperature on the long-term strength of concrete.
Resistance of Reinforced Concrete Frames to Progressive Collapse at Catenary Action of Beams
Authors: Kolchunov V. I. , Savin S. Yu.
Published: July 2024

The specific properties of deformation and failure of a reinforced concrete frame are investigated under sequential realization of arch and catenary action of beams after removal of the middle row column. Numerical modeling with the use of solid- and beam-type finite element models is performed for the purposes of the study. It was found that at the failure of the column of the second row the beam of the frame above the point of column removal transform to catenary structure, as evidenced by the relative deflection 1/29.8 (179 mm). The compressed concrete at the outer face of the corner column then collapsed, followed by the complete collapse of the frame. It is shown that the results of calculation performed with the use of the frame model based on solid finite elements were visually close to the results of numerical modeling with the use of bar finite element models before the onset of catenary action of the beams. For more correct modeling of reinforced concrete frame structures when catenary action of beams is realized in them. It is advisable to use specific modeling methods, such as accounting for additional rotations of sections at crack formation.
The Influence Of Atmosphere On Tropical Cyclone Freddy In The Lesser Sunda Islands
Authors: Fadhli Aslama Afghani
Published: July 2024

Indonesia frequently experiences atmospheric phenomena form Tropical Cyclone annually due to its geographical location situated in tropical regions. The occurrence of Tropical Cyclones in Indonesia typically lasts from 3 hours to 18 days during February to April. One of the Tropical Cyclones that occurred in Indonesia in 2023 was Tropical Cyclone Freddy. This research aims to elucidate the characteristics of Tropical Cyclone Freddy, atmospheric conditions, and its influence on rainfall in the Lesser Sunda Islands. The data utilized include Himawari-9 satellite imagery in the IR (13) band, NWP, ERA-5 meteorological parameters, and GSMaP with time intervals every 6 hours from 5-7 February 2023. Tropical Cyclone Freddy, formed south of East Nusa Tenggara on February 5, 2023, and continued to develop into a mature form on February 6, 2023, at 12:00 UTC, progressing westward. The factors contributing to the formation of this tropical cyclone include elevated Sea Surface Temperature (SST), the presence of the Intertropical Convergence Zone (ITCZ), and the active phase 4 of the Madden Julian Oscillation (MJO). The closest distance between the location of Tropical Cyclone Freddy's occurrence and the mainland occurred on February 6, 2023, at 18:00, at 187 km off Sumba Island. On the other hand, the impacts of the tropical cyclone on meteorological parameters include the occurrence of updrafts in the Lesser Sunda Islands region and an increase in moisture transport to the north and south. Additionally, Tropical Cyclone Freddy exerts a remote effect on rainfall events in the Lesser Sunda Islands.
Threshold Analysis Of Public Cemeteries For Mapping The Suitability Of New Public Cemeteries In The Future Using Remote Sensing And Geographic Information Systems In Tasikmalaya City
Authors: Valgunadi Ade Novit , Nandi  , Annisa Joviani Astari
Published: July 2024

The increasing population is causing changes in land use which are feared to be uncontrolled and forgetting one of the public facilities, namely cemeteries. The city of Tasikmalaya is an area that focuses on trade and services, is densely populated, and has a relatively small area so the provision of cemeteries land must be considered. This research aims to analyze the spatial distribution of cemeteries, capacity, thresholds, and suitability areas for cemeteries in Tasikmalaya City using Remote sensing methods and geographic information systems. The parameters used in in this study are; land use, slope, soil type, distance from rivers, distance from settlements, and distance from roads. The results of this research show that 1) Mapping the spatial distribution of cemeteries show that there are 101 cemeteries with an area of ±74 hectares with 3 TPUs, namely TPU Cieunteung, TPU Cinehel, and TPU Aisha Rashida. 2) Capacity and threshold if without an overlapping system, the public cemetery in Tasikmalaya City cannot accommodate the next 50 years, both with standard grave sizes and grave sizes from field surveys, whereas if once overlapping, the public cemetery in Tasikmalaya City cannot accommodate up to 50 years in the future if you use the size of the grave from a field survey and can accommodate up to 50 years in the future if you use the standard grave size. 3) The suitability of public cemeteries grounds show that Tasikmalaya City has suitable, quite suitable and unsuitable areas, each of which has an area of 2231 Ha, 14192 Ha and 1999 Ha. Suitable areas for cemeteries are concentrated in the northern part of Tasikmalaya City.
Exploring Hijama (Cupping Therapy) for Sciatica Relief: An Integrative Review of Unani Practices
Authors: Siddiqui Saif Ali , Shoaib Mohammad , Sultana Asia
Published: July 2024

Background: Since ancient times, Unani physicians have controlled certain illnesses by altering the metabolic process using a variety of therapeutic approaches. Some treatment tenets have been promoted by Ibne-sina (Avicenna). Regimenal therapy is a fundamental approach to treatment that aims to eradicate sick matter, control excessive production, control its spread, and resolve it by specialised approaches, ultimately restoring humoral equilibrium. Hijama (Cupping) is one such operation. The Arabic word "Hijamat" (from the phrase “Hajm”) means "volume", but it is also used to refer to sucking. Additionally, it might indicate "to minimise", "to return to basic size", or "to reduce the volume". One of the most prevalent symptoms of Irq-al-nasa (Sciatica) is lower limb neuralgic pain. This illness has the potential to become persistent and chronic, with significant socioeconomic consequences. Its overall incidence is estimated to be between 13% and 40%. Objective: Mainstream therapists primarily treat Sciatica with medication, surgery, or occasionally both. There should be an efficient substitute for evidence-based medicine because of its negative impacts, high cost, and disease-centric approach to treatment. Extensive research has been conducted to investigate the potential benefits of this traditional treatment plan for the management of Sciatica.
Keywords: Cupping, Irq-al-nasa, Sciatica, Hijama, Unani medicine
A Comparison Between Ethanolic and Aqueous Extracts of Amorphophallus paeoniifolius Tuber in Amelioration of Experimentally Induced Anxiety in Swiss Albino Mice
Authors: Sen Malini , Ghosh Niladri
Published: July 2024

Objective: Anxiety is an unpleasant emotional state. When it becomes excessive, it needs medical intervention. The intent of this study was to assess and to compare the potential of aqueous and ethanolic extracts obtained from the tuber of Amorphophallus paeoniifolius    to alleviate anxiety in Swiss albino mice.
Method: A. paeoniifolius    tuber was procured, shed dried and ground to powder. Then it was extracted using water and ethanol by cold maceration and soxhlation technique respectively. The extracts were underwent phytochemical screening. The aqueous and ethanolic extract was subsequently examined for its anxiety-reducing effects at various doses (100mg/kg, 150mg/kg and 250mg/kg) employing different animal anxiety models such as the open field test, elevated plus maze test, light and dark box test.
Result: The extracts were found to contain alkaloid, flavonoid, reducing sugar, carbohydrate, tannin, steroid and triterpenoids when they underwent phytochemical screening. Both the extract shows potent anxiolytic activity in all three animal models of anxiety when compared to control in Swiss albino mice. However, ethanolic extract shows more significant anxiolytic activity than aqueous extract. 250mg/kg ethanolic extract showed highest anxiety amelioration when compared to all other doses.
Conclusion: Amorphophallus paeoniifolius    aqueous and ethanolic extract is effective in ameliorating anxiety in Swiss albino mice.
Keywords: Amorphophallus paeoniifolius; Anxiolytic activity; Animal behavioural tests; Medicinal plants
Investigation of Mechanical Properties of Oak Sawdust Filled Polyester Composites
Authors: KARTAL İlyas , TUNÇ Mehmet
Published: July 2024

Environmentalist studies in the composites industry mostly focus on the use of polymers and reinforcement materials (fibre or filler) from sustainable sources. The production of sustainable and recyclable products due to reasons such as the rapid decrease in natural resources in the world and environmental concerns is an issue that today's industry emphasizes. In recent years, many studies have been conducted on the use of natural materials obtained from agro-food industry wastes or by-products in the production of composites due to low environmental impact, recyclability and ease of processing. In this study, it is aimed to produce an environmentally friendly composite by using oak sawdust as filler material and polyester as matrix material. Composite materials were obtained by adding sawdust to polyester in different proportions in an open mould. First of all, sawdust was brought to certain dimensions using sieves. It was added to the polyester with the open casting method starting at 5% (5, 10, 15, 20) until it reached saturation. Mechanical properties of the samples such as tensile, impact and hardness were investigated. Thus, the ideal oak sawdust filler ratio added to polyester was determined. In addition, fracture surface image analysis of composite samples was also carried out.
A systematic mapping and global perspective of herding behavior of institutional investors: A bibliometric analysis
Authors: Ebrahimi Milad , Mohiuddin Muhammad , Hosseini Elahe , Ed-Dafali Slimane , Parvin Syeda Sonia
Published: July 2024

The paper systematically identifies and discusses the factors influencing institutional investors’ herd behavior. It conducts a systematic review of the literature and bibliometric analysis of 82 papers from 1990 to 2023 using VOSviewer and CiteSpace software. The study categorizes the influential countries, institutions, journals, and articles, and outlines three main research streams: Investment strategies, financial theories, and sentiment and experience. It highlights critical factors of herding behavior in two dimensions: intra-organizational (job and management components) and extra-organizational (information and environmental components). The study serves as a valuable reference for managers and researchers, providing insights to help institutional investors understand and prevent detrimental herd behaviors in the market.
CONSTRUCTING MINDFULNESS-BASED WRITING INSTRUCTION IN GLOCALIZED LANGUAGE EDUCATION: A STUDY ON STUDENTS’ WRITING ABILITY
Authors: Marwintaria Saputri Vike Aprilianin
Published: July 2024

Writing as an academic task is considered the hardest part of English instruction and learning. Communicative skills in writing can be taught by using one strategy that is mindful learning. The purpose of this study was to provide insights into the effectiveness of mindfulness-based writing instruction in enhancing students' writing ability within the framework of glocalized language education. The study was carried out from January to April 2024 at the Jinarakkhita Buddhist College of Lampung. The population of the research was the second-semester Buddhist Communication Science Department students in the academic year 2023-2024. In this study, the researcher attempts to incorporate mindfulness into the writing process. The researcher used a rubric score to analyse and measure the students’ writing ability before and after treatment. The data were collected by administering essay writing to assess students’ writing ability. The result showed that an increase in the in the pre-test and post-test average score from 48.5 to 62. There is a significant difference in writing competency between the students who are taught by using a mindfulness-based writing instruction and the students who were taught by using conventional writing strategy. The finding showed descriptively that the students who were taught by using mindfulness-based writing instruction achieved better writing comprehension. In conclusion, the second semester students’ writing abilities have improved as a result of the use of mindfulness-based writing instruction as they are more expressive and creative in conducting the idea. Besides that, mindfulness-based writing instruction emphasizing self-awareness and presence during the writing process. It can improve productivity, mental well-being, collaboration and learning for students.
GLOCALIZATION OF LEARNING AND CREATION SOURCES FOR FICTION WRITING TEACHING MATERIALS: EXPLORING CREATIVITY IN A LOCAL CONTEXT
Authors: Lestari Sri , Sumadi Sumadi
Published: July 2024

This research aims to explore the concept of glocalization in the context of fiction writing instruction in higher education and its impact on the creation of teaching materials relevant to the local context. The primary focus of this study is to understand how the glocalization approach can enrich students' fiction writing learning experiences and support the creation of teaching materials that align with the needs and unique cultural aspects of the local context. The research methodology employed is a qualitative approach with data collection techniques including interviews, classroom observations, and document analysis. Participants in this study include faculty members and students involved in the instruction and creation of fiction writing teaching materials in several creative writing programs at universities. The findings indicate that the glocalization approach in fiction writing instruction encourages the use of local readings, the application of local language, and exploration of themes relevant to the local culture. Moreover, this approach also enhances student engagement in the learning process and strengthens their cultural identity as writers. In the context of creating fiction writing teaching materials, glocalization provides rich inspiration and material for educators to develop engaging materials that cater to the needs and uniqueness of the local culture. This research contributes to understanding the importance of integrating local elements in fiction writing instruction approaches in higher education and highlights the significant role of glocalization in creating relevant and meaningful teaching materials.
Pengaruh Fasilitas, Aksesibilitas, dan Daya Tarik Terhadap Keputusan Berkunjung ke Objek Wisata Telaga Ngebel Ponorogo
Authors: Cahyanti Hana Regita , Walyoto Sri
Published: July 2024

This research was conducted to determine the significant influence of the variables of facilities, accessibility and attractiveness on the decision to visit. Therefore, this research uses a quantitative approach. Using a purposive sampling technique with a sample of 157 respondents in Ponorogo Regency who had visited the Ngebel Lake tourist attraction twice. The types of data used are primary data and secondary data. The distribution of the questionnaire was carried out online via social media platforms such as WhatsApp which received 114 respondents and offline it was distributed by printing the questionnaire that had been made and then distributing it to 43 respondents. This research used multiple linear analysis, assisted by the IBM SPSS Statistics data analysis tool 23 to process data that has been taken by researchers. The results of this research suggest that the variables of facilities, accessibility and attractiveness have a significant and simultaneous influence on the decision to visit. So all the variables that have been studied show that they have an influence and are significant on the decision to visit the Telaga Ngebel Ponorogo tourist attraction.
Regulation of AMPK and GAPDH by transglutaminase 2 plays a pivotal role in microvascular leakage in diabetic retinas
Authors: Jeon Hye-Yoon , Lee Ah-Jun , Moon Chan-Hee , Ha Kwon-Soo
Published: July 2024

ABSTRACT

Diabetic retinopathy is the most common microvascular complication caused by chronic hyperglycemia and is a leading cause of blindness; however, the underlying molecular mechanism has not been clearly elucidated. Thus, we investigated whether regulation of AMP-activated protein kinase (AMPK) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) by transglutaminase 2 (TGase2) is important for hyperglycemia-induced microvascular leakage in the diabetic retina. In HRECs and diabetic mouse retinas, we found that TGase2, activated by sequential elevation of intracellular Ca2+ and reactive oxygen species (ROS) levels, played an essential role in hyperglycemia-induced vascular leakage. ROS generation and TGsae2 activation were involved in hyperglycemia-induced AMPK dephosphorylation, which resulted in VE-cadherin disassembly and increased fluorescein isothiocyanate-dextran extravasation. Furthermore, high glucose-induced TGase2 activation suppressed GAPDH activity, determined by an on-chip activity assay, through inhibition of AMPK, which induced VE-cadherin disassembly and endothelial permeability in HRECs. Overall, our findings suggest that inhibition of AMPK and GAPDH by TGase2 plays a pivotal role in hyperglycemia-induced microvascular leakage in the retinas of diabetic mice.

Highlights

• ROS-mediated activation of TGase2 inhibited AMPK in the diabetic retina.

• AMPK inhibition resulted in VE-cadherin disassembly and microvascular leakage.

• TGase2 suppressed GAPDH activity and induced endothelial permeability through AMPK inhibition.

• Inhibition of AMPK and GAPDH by TGase2 is important for microvascular leakage in the diabetic retina.
Ventanas del gobierno abierto: Análisis de la política pública y salud de las mujeres mexiquenses en sus retornos de EUA
Authors: Sánchez-Ramos Miguel Ángel , Chávez Herrera Marisol
Published: July 2024

Este estudio examinó la función asumida por el gobierno abierto en las trayectorias migratorias y de salud, así como los factores que inciden en la implementación de políticas públicas dirigidas a mujeres migrantes internacionales que viajan de América a Estados Unidos y luego regresan a sus países de origen. Durante el proceso de regreso, se investigó la participación de los actores sociales en los programas de salud y su vinculación con el gobierno abierto. Además, se analizaron los marcos legales a nivel nacional, estatal y municipal que respaldan los derechos de las migrantes con el fin de examinar la política pública. Para comprender mejor sus experiencias, se utilizó un enfoque cualitativo que incluyó análisis de narrativas a través de entrevistas semiestructuradas, desde una perspectiva constructivista. Los resultados revelan la diversidad de estrategias adoptadas por las mujeres migrantes para abordar los problemas de salud, como recurrir a servicios privados debido a barreras de acceso y a la brecha digital, por lo que se propone ampliar las oportunidades del gobierno abierto. Estos hallazgos sirven de sustento para continuar evaluando las dificultades que enfrenta el gobierno abierto y promueven la formulación de una agenda inclusiva que garantice, a través de la gestión de políticas públicas, el acceso gratuito a los servicios de salud para las mujeres que regresan.
Fantasmas de vitrine
Authors: Roque Maura Voltarelli
Published: July 2024

Este artigo propõe outro modo de olhar a poesia de Drummond por meio da análise do poema “A loja feminina”. A partir de uma metodologia da montagem de tempos, gêneros e linguagens artísticas diversas, buscamos abrir, de maneira fantasmal e erótica (sem esquecer a ambiguidade do erotismo visto por Georges Bataille), um poema que, em um jogo cênico de espelhos, artifícios e ornamentos, explora a fascinação da palavra feita imagem, da imagem feita palavra. No desenlace da cena dramática, leitor e poeta se dissolvem no “enigma de formas permutantes”, a restar como mais um, entre tantos, nomes da Ninfa, essa singular personagem teórica de Aby Warburg, reproposta na contemporaneidade por Georges Didi-Huberman, presença espectral a invadir os versos. Eis que nos, movimentos tardios dessa obra poética movediça, descobrimos uma vida mais intensa – a vida das imagens, pensada por Baudelaire, Walter Benjamin, Giorgio Agamben e Emanuele Coccia.
Imaginação poética e complexo de cultura
Authors: Munhoz Erica Martinelli
Published: July 2024

Este trabalho tem por objetivo compreender como a imagem poética, a imaginação material e o complexo de cultura, conceitos bachelardianos fundamentais, podem ser produtivos na leitura da poesia de Fiama Hasse Pais Brandão, particularmente de seus poemas que reconfiguram e atualizam a relação entre a tradição poética e a temática do canto do cisne. Fundamental na revolução da poesia portuguesa a partir da Poesia 61, para a qual a imagem é um tema importante, a obra de Brandão “revolucionou o imaginismo primitivo” (Cruz, 2008). O potencial transformador da imagem poética em diálogo com topos literários por vezes desgastados (Bachelard, 2016) espelha-se na forma como a poeta portuguesa cria imagens poéticas originais que renovam sua relação com a tradição. Pretende-se contribuir, assim, para a atualização das leituras de uma poeta fundamental, bem como para o reconhecimento da atualidade do pensamento bachelardiano na crítica literária hoje.
Poe na Psicanálise
Authors: Silva Jorge Francisco da , Carvalho Glória Maria Monteiro de , Melo Maria de Fátima Vilar de
Published: July 2024

Este artigo explora ligações entre Literatura, Linguística e Psicanálise, a partir do seminário de Lacan (1995/1998) sobre o conto “A carta roubada”, de Edgar Allan Poe. Lacan recorre não apenas ao trabalho de Freud sobre a repetição como também à noção da ordem simbólica desenvolvida por Saussure e Jakobson. Lacan analisa a relação entre o automatismo de repetição, a insistência da cadeia significante, a ordem simbólica e as formações do inconsciente. Além de considerações sobre a arte da composição e da predominância das cadeias significantes na obra de Poe, também são discutidas a relação entre a noção lacaniana de inconsciente estruturado como uma linguagem e a determinação do sujeito pelo significante. Entendemos que a trama urdida por Poe funciona como uma analogia da autonomia das cadeias significantes sobre a significação, à medida que permite acompanhar a evolução da história mesmo sem informações acerca do conteúdo da carta.
Representações dos navios de escravizados
Authors: Oliveira Leonardo Davino de , Jeucken Carla
Published: July 2024

Este trabalho tem por objetivo investigar as diferentes perspectivas assumidas pelo eu-poético e pelo eu-cancional em uma sequência de poemas e canções afins, consideradas as distintas contextualizações nas quais despontaram. Pelas indagações – quem fala? e quem canta? – direcionadas a cada uma das criações selecionadas, discorremos sobre os deslocamentos do enunciador, ocasionados pelos (re)arranjos estéticos (transpoético, temático e vocoperformático) em cada uma das obras. Para fundamentação teórica e análise dos poemas escritos, respaldamo-nos, especialmente, nos trabalhos de Campos (1986), Kotte (2000) e Meyer (2002) e, para as discussões sobre as vocoperfomances, valemo-nos de embasamentos encontrados, sobretudo, em Tatit (1996), Molina (2016) e Zumthor (1997). Concluídas as análises e comparações de três poemas – “Das Sklavenschiff” (Heine), “Le Negrier” (Nerval) e “O navio negreiro” (Alves) – e duas vocoperformances de excertos dos poemas – (Veloso, 1997) e (Reichel, 2003) –, observamos os efeitos que tais deslocamentos do texto escrito para o cantado engendram.
Saudades do mundo
Authors: Sterzi Eduardo
Published: July 2024

Descrição:Entrevista com o professor Eduardo Sterzi, mestre em Teoria da Literatura pela Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS, 2000) e doutor em Teoria e História Literária pela Universidade Estadual de Campinas (UNICAMP, 2006). Realizou pesquisas de pós-doutorado na Universidade de São Paulo (USP) e na Università degli Studi di Roma "La Sapienza". Desde 2012, é professor de Teoria Literária no Instituto de Estudos da Linguagem da UNICAMP e, entre 2016 e 2020, foi coordenador do Programa de Pós-Graduação em Teoria e História Literária da mesma universidade. Tem experiência na área de Letras, com ênfase em Teoria da Literatura, assim como em relações entre literatura e as outras artes, especialmente fotografia, desenho e pintura, além de relações entre filologia e história da arte. É autor do livro de poemas Aleijão (7Letras, 2009), além de diversos livros de crítica literária, dentre os quais destacamos, Saudades do mundo: notícias da Antropofagia. (Todavia, 2022).
Edição: Ana Paula Rodrigues da Silva (USP), Thiago Fonseca (TV-PUC)Música: PIPA estúdio
Revista FronteiraZ 32 – julho/2024
A Brief Review on Immunology of Dental Caries and Caries Vaccine
Authors: Ghosal Rhitam , Gayen Swagata , Mahmud Sk. Abdul , Das Sanjeet Kumar , Pal Mousumi
Published: July 2024

Dental caries is an irreversible microbial disease of the calcified tissues of the teeth, characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth, which often leads to cavitation. Untreated dental caries in deciduous teeth was the tenth most widespread and the fourth most expensive chronic illness to treat condition among children worldwide, with prevalence peaking at the age of six. Individuals with active caries have an elevated serum antibody level for mutans streptococci. Findings also suggest that an increased antigenic load (bacteria from lesions) will give rise to elevated salivary antibody. Subjects with selective IgA deficiency without salivary antibody show markedly elevated levels of dental caries when compared to normal controls. IgA deficient subjects with IgM compensatory antibodies have significantly less caries than simply IgA deficient subjects. The immune system in secretions have been used to interfere with caries by stimulating salivary antibodies to appropriate antigens. The gingival crevicular fluid contributes IgG, which can also interfere with caries.
This review article emphasizes the comprehensive and contemporary idea about immunological aspect of dental caries along with overview on dental caries and immunity and recent advancements in the field of caries vaccine.
PELATIHAN OPERASIONAL MICRO-XRF DI LABORATORIUM TEKNIK KEBUMIAN FAKULTAS SAINS DAN TEKNOLOGI UNIVERSITASI JAMBI
Authors: Utama Hari Wiki , Aulia Mega
Published: July 2024

Di era globalisasi saat ini kebutuhan akan hasil penelitian yang detail, cepat, dan akuisisi di bidang ilmu dan teknologi pada era globalisasi saat ini sangat dibutuhkan, terutama dalam riset sumber daya alam. Penentuan adanya potensi dan indikasi dari keberadaan logam dasar seperti emas, logam tanah jarang dan logam jejak yang merupakan mineral kritis merupakan salah satu target temuan saat ini yang membutuhkan metode analisis yang akurat. Dengan metode analisis micro-XRF (μ-XRF) yang dapat mengidentifikasi unsur dari material ataupun mineral yang terkandung pada suatu objek dapat terdeteksi dengan baik, meliputi penyebaran dan persentase kehadirannya dengan teknik analisis yang menggunakan Sinar-X untuk mengetahui komposisi kimia suatu sampel. Sehingga dengan metode ini dapat menjadi solusi yang tepat digunakan untuk mengindentifikasi suatu material. Dengan demikian seiring meningkatnya riset di bidang material dengan kebutuhan analisis unsur-unsur yang sulit teridentifikasi yang dulunya menjadi krusial, namun saat ini sudah terjawab dengan menggunakan metode analisis micro-XRF. Pelaksanaan kegiatan pelatihan operasional ini dilakukan dengan beberapa tahapan, meliputi tahapan materikulasi, preparasi dan jenis sampel, tahapan selanjutnya operasional penggunaan alat, dan tahapan terakhir adalah evaluasi dari kegiatan yang dilakukan. Kegiatan ini dilaksanakan di Laboratorium Teknik Kebumian, Fakultas Sains dan Teknologi, Universitas Jambi dengan peserta berasal dari teknisi dan analisis (laboran) di semua laboratorium yang berada di Fakultas Sains dan Teknologi, Universitas Jambi. Dalam melaksanakan pelatihan ini, Laboratorium Kebumian didukung oleh narasumber utama dari PT. Dynatech Internasional untuk memberikan pelatihan operasional dari micro-XRF. Alat yang digunakan dalam pelatihan ini adalah micro-XRF dari Bruker dan Dynatech, satu set komputer yang telah dilengkapi dengan perangkat lunak micro-XRF di dalamnya. Peralatan yang digunakan sebelumnya sudah dilakukan instalasi, artinya peralatan yang digunakan untuk pelatihan ini siap untuk dioperasikan. Alat ini sudah terhubung dengan satu set perangkat komputer untuk melihat objek yang akan diamati melalui monitor komputer yang tersedia. Bahan yang digunakan dalam pelatihan ini berupa sampel batuan yang telah diratakan di bagian atasnya, serbuk batuan, chip komputer, lem perekat sampel, parafin, kertas karbon, mortar dan stampler, dan wadah sampel.
Development of interactive multimedia based on articulate storyline to improve students' creative thinking skills on support solution materials
Authors: Ananda Wulan Rizqi , Iriani Rilia , Hamid Abdul
Published: July 2024

This research aims to create a product in the form of interactive multimedia based on an articulate storyline using buffer solution material that is feasible, practical, and effective for improving students' creative thinking skills. The research method used in this development is Research and Development (R&D) with a development model, namely 4D: define, design, develop, and disseminate. Interactive multimedia based on an articulate storyline was tested on 34 class XI MIPA 1 MAN 2 Banjarmasin City students. The research results indicate that interactive multimedia based on an articulate storyline has been developed: (1) Worthy in terms of the appropriateness of content, language, visual appearance, audiovisual, and application; (2) Very practical in individual trials and small group trials; (3) Very practical from the students' responses and very good from the teacher's teaching activities; (4) Effective based on the N-gain value of students' creative thinking skills is in the medium category. Interactive multimedia based on an articulate storyline in buffer solution material to improve students' creative thinking skills is declared feasible, practical, and effective.