bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the Protein Quality, In Vitro Intestinal Iron Absorption and Human Faecal Microbiota Impacts of Plant-Based Mince
Authors: Belobrajdic Damien P. , Osborne Simone , Conlon Michael , Brook Henri , Addepalli Rama , Muhlhausler Beverly S.
Published: July 2024

The nutritional quality of plant-based meat analogues compared to traditional meat products has been questioned in recent commentary, particularly in relation to protein quality and micronutrient bioavailability. However, the attributes of specific products within this category are unclear. We therefore undertook a comprehensive assessment of the compositional and functional attributes of v2food® (Sydney, Australia) plant-based mince, including an assessment of the effects of reformulation, including the addition of amino acids, ascorbic acid, and different forms of elemental iron. The protein digestibility and protein quality of v2food® plant-based mince were comparable to beef mince in the standardized INFOGEST system, and favourable effects on microbiota composition and short-chain fatty acid (SCFA) production were demonstrated in an in vitro digestion system. The use of ferrous sulphate as an iron source improved in vitro intestinal iron absorption by ~50% in comparison to other forms of iron (p < 0.05), although levels were ~3-fold lower than beef mince, even in the presence of ascorbic acid. In conclusion, the current study identified some favourable nutritional attributes of plant-based v2food® mince, specifically microbiota and SCFA changes, as well as other areas where further reformulation could be considered to further enhance the bioavailability of key nutrients. Further studies to assess the effect of plant-based meat analogues on health measures in vivo will be important to improve knowledge in this area.
Hesperetin Alleviated Experimental Colitis via Regulating Ferroptosis and Gut Microbiota
Authors: Wang Jinzhi , Yao Yuanyuan , Yao Ting , Shi Qingmiao , Zeng Yifan , Li Lanjuan
Published: July 2024

Hesperetin (HT) is a type of citrus flavonoid with various pharmacological activities, including anti-tumor, anti-inflammation, antioxidant, and neuroprotective properties. However, the role and mechanism of HT in ulcerative colitis (UC) have been rarely studied. Our study aimed to uncover the beneficial effects of HT and its detailed mechanism in UC. Experimental colitis was induced by 2.5% dextran sodium sulfate (DSS) for seven days. HT ameliorated DSS-induced colitis in mice, showing marked improvement in weight loss, colon length, colonic pathological severity, and the levels of TNFα and IL6 in serum. A combination of informatics, network pharmacology, and molecular docking identified eight key targets and multi-pathways influenced by HT in UC. As a highlight, the experimental validation demonstrated that PTGS2, a marker of ferroptosis, along with other indicators of ferroptosis (such as ACSL4, Gpx4, and lipid peroxidation), were regulated by HT in vivo and in vitro. Additionally, the supplement of HT increased the diversity of gut microbiota, decreased the relative abundance of Proteobacteria and Gammaproteobacteria, and restored beneficial bacteria (Lachnospiraceae_NK4A136_group and Prevotellaceae_UCG-001). In conclusion, HT is an effective nutritional supplement against experimental colitis by suppressing ferroptosis and modulating gut microbiota.
Galangin: A Promising Flavonoid for the Treatment of Rheumatoid Arthritis—Mechanisms, Evidence, and Therapeutic Potential
Authors: Khawaja Ghada , El-Orfali Youmna , Shoujaa Aya , Abou Najem Sonia
Published: July 2024

Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by progressive joint inflammation and damage. Oxidative stress plays a critical role in the onset and progression of RA, significantly contributing to the disease’s symptoms. The complex nature of RA and the role of oxidative stress make it particularly challenging to treat effectively. This article presents a comprehensive review of RA’s development, progression, and the emergence of novel treatments, introducing Galangin (GAL), a natural flavonoid compound sourced from various plants, as a promising candidate. The bioactive properties of GAL, including its anti-inflammatory, antioxidant, and immunomodulatory effects, are discussed in detail. The review elucidates GAL’s mechanisms of action, focusing on its interactions with key targets such as inflammatory cytokines (e.g., TNF-α, IL-6), enzymes (e.g., SOD, MMPs), and signaling pathways (e.g., NF-κB, MAPK), which impact inflammatory responses, immune cell activation, and joint damage. The review also addresses the lack of comprehensive understanding of potential treatment options for RA, particularly in relation to the role of GAL as a therapeutic candidate. It highlights the need for further research and clinical studies to ascertain the effectiveness of GAL in RA treatment and to elucidate its mechanisms of action. Overall, this review provides valuable insights into the potential of GAL as a therapeutic option for RA, shedding light on its multifaceted pharmacological properties and mechanisms of action, while suggesting avenues for future research and clinical applications.
Uncovering the Therapeutic Potential of Lithium Chloride in Type 2 Diabetic Cardiomyopathy: Targeting Tau Hyperphosphorylation and TGF-β Signaling via GSK-3β Inhibition
Authors: Abou Assi Layal , Alkhansa Sahar , Njeim Rachel , Ismail Jaafar , Madi Mikel , Ghadieh Hilda E. , Al Moussawi Sarah , Azar Tanya S. , Ayoub Maurice , Azar William S. , Hamade Sarah , Nawfal Rashad , Haddad Nina-Rossa , Harb Frederic , Faour Wissam , Khalil Mahmoud I. , Eid Assaad A.
Published: July 2024

Diabetic cardiomyopathy (DCM) is a major complication of type 2 diabetes mellitus (T2DM) that leads to significant morbidity and mortality. The alteration in the signaling mechanism in diabetes leading to cardiomyopathy remains unclear. The purpose of this study is to investigate the role of tauopathy in myocardial dysfunction observed in T2DM. In that regard, diabetic Sprague Dawley rats were treated with intraperitoneal injections of lithium chloride (LiCl), inhibiting tau phosphorylation. Cardiac function was evaluated, and molecular markers of myocardial fibrosis and the TGF-β signaling were analyzed. T2DM rats exhibited a decline in ejection fraction and fractional shortening that revealed cardiac function abnormalities and increased myocardial fibrosis. These changes were associated with tau hyperphosphorylation. Treating diabetic rats with LiCl attenuated cardiac fibrosis and improved myocardial function. Inhibition of GSK-3β leads to the suppression of tau phosphorylation, which is associated with a decrease in TGF-β expression and regulation of the pro-inflammatory markers, suggesting that tau hyperphosphorylation is parallelly associated with fibrosis and inflammation in the diabetic heart. Our findings provide evidence of a possible role of tau hyperphosphorylation in the pathogenesis of DCM through the activation of TGF-β and by inducing inflammation. Targeting the inhibition of tau phosphorylation may offer novel therapeutic approaches to reduce DCM burden in T2DM patients.
Novel Genetic Variants Explaining Severe Adverse Drug Events after Clinical Implementation of DPYD Genotype-Guided Therapy with Fluoropyrimidines: An Observational Study
Authors: Díaz-Villamarín Xando , Martínez-Pérez María , Nieto-Sánchez María Teresa , Ruiz-Tueros Gabriela , Fernández-Varón Emilio , Torres-García Alicia , González Astorga Beatriz , Blancas Isabel , Iáñez Antonio J. , Cabeza-Barrera José , Morón Rocío
Published: July 2024

Fluoropyrimidines (FPs) are commonly prescribed in many cancer streams. The EMA and FDA-approved drug labels for FPs recommend genotyping the DPYD*2A (rs3918290), *13 (rs55886062), *HapB3 (rs56038477), alleles, and DPYD rs67376798 before treatment starts. We implemented the DPYD genotyping in our daily clinical routine, but we still found patients showing severe adverse drug events (ADEs) to FPs. We studied among these patients the DPYD rs1801265, rs17376848, rs1801159, rs1801160, rs1801158, and rs2297595 as explanatory candidates of the interindividual differences for FP-related toxicities, examining the association with the response to FPs . We also studied the impact of DPYD testing for FP dose tailoring in our clinical practice and characterized the DPYD gene in our population. We found a total acceptance among physicians of therapeutic recommendations translated from the DPYD test, and this dose tailoring does not affect the treatment efficacy. We also found that the DPYD*4 (defined by rs1801158) allele is associated with a higher risk of ADEs (severity grade ≥ 3) in both the univariate (O.R. = 5.66; 95% C.I. = 1.35–23.67; p = 0.014) and multivariate analyses (O.R. = 5.73; 95% C.I. = 1.41–28.77; p = 0.019) among FP-treated patients based on the DPYD genotype. This makes it a candidate variant for implementation in clinical practice.
A Fault Direction Criterion Based on Post-Fault Positive-Sequence Information for Inverter Interfaced Distributed Generators Multi-Point Grid-Connected System
Authors: Yang Fan , Chen Hechong , Han Gang , Xu Huiran , Lei Yang , Hu Wei , Fan Shuxian
Published: July 2024

In response to the poor reliability in identifying fault direction in distribution networks with Inverter Interfaced Distributed Generators (IIDGs), considering the control strategy of low-voltage ride-through, a fault direction criterion based on post-fault positive-sequence steady-state components is proposed. Firstly, the output steady-state characteristics of IIDGs considering the low-voltage ride-through capability are analyzed during grid failure, and the applicability of existing directional elements in a distribution network with IIDGs connected dispersively is demonstrated. Subsequently, for the typical structure of an active distribution grid operating under flexible modes, the positive-sequence voltage and current are examined in various fault scenarios, and a reliable direction criterion is suggested based on the difference in post-fault positive-sequence impedance angles on different sides of the lines that are suitable whether on the grid side or the IIDG side. Lastly, the reliability of the proposed direction criterion is verified by simulation and the results indicate that the fault direction can be correctly determined, whereas phase-to-phase and three-phase short circuit faults occur in different scenarios, independent of the penetration and grid-connected positions of IIDGs, fault location, and transition resistance. It is suitable for fault direction discrimination of an IIDGs multi-point grid-connected system under a flexible operation mode.
Tree Canopy Volume Extraction Fusing ALS and TLS Based on Improved PointNeXt
Authors: Sun Hao , Ye Qiaolin , Chen Qiao , Fu Liyong , Xu Zhongqi , Hu Chunhua
Published: July 2024

Canopy volume is a crucial biological parameter for assessing tree growth, accurately estimating forest Above-Ground Biomass (AGB), and evaluating ecosystem stability. Airborne Laser Scanning (ALS) and Terrestrial Laser Scanning (TLS) are advanced precision mapping technologies that capture highly accurate point clouds for forest digitization studies. Despite advances in calculating canopy volume, challenges remain in accurately extracting the canopy and removing gaps. This study proposes a canopy volume extraction method based on an improved PointNeXt model, fusing ALS and TLS point cloud data. In this work, improved PointNeXt is first utilized to extract the canopy, enhancing extraction accuracy and mitigating under-segmentation and over-segmentation issues. To effectively calculate canopy volume, the canopy is divided into multiple levels, each projected into the xOy plane. Then, an improved Mean Shift algorithm, combined with KdTree, is employed to remove gaps and obtain parts of the real canopy. Subsequently, a convex hull algorithm is utilized to calculate the area of each part, and the sum of the areas of all parts multiplied by their heights yields the canopy volume. The proposed method’s performance is tested on a dataset comprising poplar, willow, and cherry trees. As a result, the improved PointNeXt model achieves a mean intersection over union (mIoU) of 98.19% on the test set, outperforming the original PointNeXt by 1%. Regarding canopy volume, the algorithm’s Root Mean Square Error (RMSE) is 0.18 m3, and a high correlation is observed between predicted canopy volumes, with an R-Square (R2) value of 0.92. Therefore, the proposed method effectively and efficiently acquires canopy volume, providing a stable and accurate technical reference for forest biomass statistics.
Infrared Image Super-Resolution Network Utilizing the Enhanced Transformer and U-Net
Authors: Huang Feng , Li Yunxiang , Ye Xiaojing , Wu Jing
Published: July 2024

Infrared images hold significant value in applications such as remote sensing and fire safety. However, infrared detectors often face the problem of high hardware costs, which limits their widespread use. Advancements in deep learning have spurred innovative approaches to image super-resolution (SR), but comparatively few efforts have been dedicated to the exploration of infrared images. To address this, we design the Residual Swin Transformer and Average Pooling Block (RSTAB) and propose the SwinAIR, which can effectively extract and fuse the diverse frequency features in infrared images and achieve superior SR reconstruction performance. By further integrating SwinAIR with U-Net, we propose the SwinAIR-GAN for real infrared image SR reconstruction. SwinAIR-GAN extends the degradation space to better simulate the degradation process of real infrared images. Additionally, it incorporates spectral normalization, dropout, and artifact discrimination loss to reduce the potential image artifacts. Qualitative and quantitative evaluations on various datasets confirm the effectiveness of our proposed method in reconstructing realistic textures and details of infrared images.
The Identification of Manure Spreading on Bare Soil through the Development of Multispectral Indices from Sentinel-2 Data: The Emilia-Romagna Region (Italy) Case Study
Authors: Dubbini Marco , Belluzzo Maria , Zanni Bertelli Villiam , Pirola Alessandro , Tornato Antonella , Alessandrini Cinzia
Published: July 2024

Satellite remote sensing is currently an established, effective, and constantly used tool and methodology for monitoring agriculture and fertilisation. At the same time, in recent years, the need for the detection of livestock manure and digestate spreading on the soil is emerging, and the development of spectral indices and classification processes based on satellite multispectral data acquisitions is growing. However, the application of such indicators is still underutilised and, given the polluting impact of livestock manure and digestate on soil, groundwater, and air, an in-depth study is needed to improve the monitoring of this practice. Additionally, this paper aims at exposing a new spectral index capable of detecting the land affected by livestock manure and digestate spreading. This indicator was created by studying the spectral response of bare soil and livestock manure and digestate, using Copernicus Sentinel-2 MSI satellite acquisitions and ancillary datasets (e.g., soil moisture, precipitation, regional thematic maps). In particular, time series of multispectral satellite acquisitions and ancillary data were analysed, covering a survey period of 13 months between February 2022 and February 2023. As no previous indications on fertilisation practices are available, the proposed approach consists of investigating a broad-spectrum area, without investigations of specific test sites. A large area of approximately 236,344 hectares covering three provinces of the Emilia-Romagna Region (Italy) was therefore examined. A series of ground truth points were also collected for assessing accuracy by filling in the confusion matrix. Based on the definition of the spectral index, a value of the latter greater than three provides the most conservative threshold for detecting livestock manure and digestate spreading with an accuracy of 62.53%. Such results are robust to variations in the spectral response of the soil. On the basis of these very encouraging results, it is considered plausible that the proposed index could improve the techniques for detecting the spreading of livestock manure and digestate on bare ground, classifying the areas themselves with a notable saving of energy compared to the current investigation methodologies directly on the ground.
Energy Harvesting Technologies and Applications for the Internet of Things and Wireless Sensor Networks
Authors: Naifar Slim , Kanoun Olfa , Trigona Carlo
Published: July 2024

The field of Internet of Things (IoT) technologies is advancing rapidly, driven by the critical need for autonomous and sustainable wireless sensor networks [...]
Pollen-Modified Flat Silk Cocoon Pressure Sensors for Wearable Applications
Authors: Wang Shengnan , Wang Yujia , Wang Yi , Liu Jiaqi , Liu Fan , Dai Fangyin , Li Jiashen , Li Zhi
Published: July 2024

Microstructures have been proved as crucial factors for the sensing performance of flexible pressure sensors. In this study, polypyrrole (PPy)/sunflower pollen (SFP) (P/SFP) was prepared via the in situ growth of PPy on the surface of degreased SFP with a sea urchin-like microstructure; then, these P/SFP microspheres were sprayed onto a flat silk cocoon (FSC) to prepare a sensing layer P/SFP-FSC. PPy-FSC (P-FSC) was prepared as an electrode layer through the in situ polymerization of PPy on the FSC surface. The sensing layer P/SFP-FSC was placed between two P-FSC electrode layers to assemble a P/SFP-FSC pressure sensor together with a fork finger electrode. With 6 mg/cm2 of optimized sprayed P/SFP microspheres, the prepared flexible pressure sensor has a sensitivity of up to 0.128 KPa−1 in the range of 0–13.18 KPa and up to 0.13 KPa−1 in the range of 13.18–30.65 KPa, a fast response/recovery time (90 ms/80 ms), and a minimum detection limit as low as 40 Pa. This fabricated flexible P/SFP-FSC sensor can monitor human motion and can also be used for the encrypted transmission of important information via Morse code. In conclusion, the developed flexible P/SFP-FSC pressure sensor based on microstructure modification in this study shows good application prospects in the field of human–computer interaction and wearable electronic devices.
Closing the Loop: Can Anaerobic Digestates from Food Waste Be Universal Source of Nutrients for Plant Growth?
Authors: Cichy Piotr , Tomczak-Wandzel Renata , Szatkowska Beata , Kalka Joanna , Yadav Ravi Shankar
Published: July 2024

Reducing waste production and improving waste treatment are key objectives in the EU’s Circular Economy Action Plan. Anaerobic digestion of food waste is a promising method, but safely disposing of its by-products, which contain valuable nutrients like nitrogen, phosphorus, and organic matter, remains a challenge. These nutrients suggest potential use in agriculture to enhance sustainability, yet their effects on plant growth need thorough understanding. This study investigated the impact of liquid digestates from anaerobic digestion of food waste, combined with fish sludge (from recirculated aquaculture systems), on plant growth (Lepidium sativum and Triticum aestivum) through direct soil tests. The content of biogenic elements in the digestates did not differ and was 0.32% for N, <0.05% for P, and 0.15% for K. Two tests were conducted, both using artificial soil prepared to OECD 207 standards: the Phytotoxkit™ test (ISO 18763:2016) and a pot experiment (OECD 208). Results showed that digestates initially delayed germination and hindered early plant growth, an effect that diminished over time. This may be due to the high organic matter content of digestates, similar to standard fertilizers like manure or compost. Pre-incubating digestates in soil before application, similar to common agricultural practices with soil amendments, is suggested as a potential solution.
Research on the Impact of Digital-Real Integration on Logistics Industrial Transformation and Upgrading under Green Economy
Authors: Liu Zhiqiang , Zhao Yaping , Guo Caiyun , Xin Ziwei
Published: July 2024

Digital-real integration and green economy have become an important driving force to propel logistics industrial transformation upgrading and sustainable development. This paper analyzed the impact of digital-real integration on the transformation and upgrading of the logistics industry and the role of green economy from the perspectives of endogenous growth theory, green development theory, and industrial organization theory. Utilizing the panel data spanning 2013 to 2022 from 11 cities in Hebei Province, China, this study established the measurement indicator systems of logistics industrial transformation and upgrading, digital-real integration, and green economy, and measured the integrated developmental level employing an entropy weight–TOPSIS–grey correlation model. Further, the benchmark regression model, moderation effect model, and threshold effect model were applied to delve into the influence mechanism of logistics industrial transformation and upgrading influenced by digital-real integration under the green economy. The research results showed that: Digital-real integration contributed favorably to the transformation and upgrading of the logistics industry. The green economy exerted a beneficial moderating influence on the process, where digital-real integration affected the transformation upgrading of the logistics industry, and the moderating effect of the innovation elements was significantly the strongest. Digital-real integration exhibited a single threshold effect, and the moderating impact of the green economy also had a single threshold condition, and once both thresholds were surpassed, digital-real integration significantly promoted the logistics industrial reformation and upgrading. Drawing from the aforementioned conclusions, this study advanced development recommendations in terms of strengthening regional cooperation, intensifying digital-real integration, exerting the effect of the green economy, and establishing dynamic monitoring and evaluation mechanisms.
Ideals in Bipolar Quantum Linear Algebra
Authors: Laipaporn Kittipong , Khachorncharoenkul Prathomjit
Published: July 2024

Since bipolar quantum linear algebra (BQLA), under two operations–-addition and multiplication—demonstrates the properties of semirings, and since ideals play an important role in abstract algebra, our results are compelling for the ideals of a semiring. In this article, we investigate the characteristics of ideals, principal ideals, prime ideals, maximal ideals, and the smallest ideal containing any nonempty subset. By applying elementary real analysis, particularly the infimum, our main result is stated as follows: for any closed set I in BQLA, I is a nontrivial proper ideal if and only if there exists c∈(0,1] such that I=(−x,y)∈R2|cx≤y≤xcandx,y≥0. This shows that its shape has to be symmetric with the graph y=−x.
Experimental Study on Impedance Spectrum-Based Detection of Water Holdup in Two-Phase Flow under Complex Salinity Conditions
Authors: Cheng Linfeng , Ke Shizhen , Shi Hongwei , Zhang Yuhang , Luo Hu , Hu Hao
Published: July 2024

In industrial production and water resource management involving fluid flows, two-phase flow measurement in complex environments has always been a research hotspot. In this study, a broadband detection device (40–110 MHz) suitable for two-phase flow in pipes was designed in a laboratory environment, the impedance response of two-phase flow was investigated under different salinity conditions and flow patterns, and a new impedance dispersion model suitable for two-phase flow in pipes was built. The experimental results show that the new model can better describe the rules of impedance dispersion in two-phase flow and is universally applicable, and that the equivalent solution resistance and interfacial polarization frequency have a stable functional relationship with water holdup. Based on the static experimental results, water holdup evaluation models for four flow patterns were established, and the dynamic detection results were predicted. The prediction results show that the new method proposed herein is not affected by changes in salinity and flow pattern when the flow pattern is known, and that its accuracy can meet the production requirements. This study expands the application range of traditional single-frequency conductivity detection techniques and provides a new idea for the development and improvement of systems for online detection of water holdup in two-phase flow.
Influence of Temperature on the Toxic Effects of Carbamazepine on the Copepod Tigriopus fulvus: A Transgenerational Full Life Cycle Study
Authors: Parlapiano Isabella , Prato Ermelinda , Denti Giuseppe , Biandolino Francesca
Published: July 2024

Coastal areas are increasingly exposed to global warming and emerging contaminants from anthropogenic activities; however, the interactive effects of these stress factors in shaping the offspring’s vulnerability to them are poorly understood. The present study aimed to assess the influence of temperature on the toxicity of the pharmaceutical carbamazepine (CBZ) in the parental (F0) and in the first (F1) generation of Tigriopus fulvus, through a full life cycle study, measuring several biological parameters. At control temperature (20 °C), exposure to CBZ significantly inhibited larval development, especially in the F1 generation. In contrast, under warmer conditions (27 °C), even after exposure to CBZ, the development was stimulated, proving that temperature was the main factor influencing it. As regards the other investigated life traits (body length, sex ratio, and fecundity), both temperature and generation modulated toxic effects of CBZ, which is evidenced by the onset of higher alterations in F1 co-exposed copepods. Our findings suggest that temperature and contaminants could increase the long-term vulnerability to stressors of T. fulvus, potentially affecting the population structure over multiple generations of exposure.
Hubungan Tingkat Pengetahuan dengan Sikap Ibu Hamil tentang Pandemi COVID-19 di Wilayah Kerja UPT. Kesmas Ubud I
Authors: Mas Swandewi Luh Made , Hartati Ni Nyoman , Suratiah Sur , Runiari Nengah , Ruspawan Dewa Made
Published: July 2024

Knowledge is thoughts, understandings, ideas, concepts to make decisions and solve problems. Good knowledge will form a favorable attitude. This study aims to determine the relationship between the level of knowledge and attitudes of pregnant women about the COVID-19 pandemic in the UPT. Kesmas Ubud I,Gianyar. This research is correlational with cross sectional approach using non-probability sampling with purposive sampling technique. The population in this study were all pregnant women who used WhatsApp totaling 65 pregnant women with a sample size of 47 samples. Data in the form of primary data, namely the identity of pregnant women, knowledge of COVID-19 and attitudes of pregnant women towards COVID-19 by filling out an online questionnaire. The results showed that 44 pregnant women (93.6%) had a good level of knowledge and 42 pregnant women (89.4%) had favorable attitudes. Bivariate analysis with Spearman rank test obtained p (0.001) alpha (0.05), there is a relationship between the level of knowledge and the attitude of pregnant women about the COVID-19 pandemic in the UPT. Kesmas Ubud I, Gianyar. Researchers hope that health workers provide education to pregnant women with a sufficient level of knowledge about COVID-19.
Hubungan Dukungan Suami dengan Kepatuhan Ibu dalam Penggunaan Kontrasepsi Suntik pada Masa Pandemi COVID-19
Authors: Prema Devi I Gusti Ayu Istri , Astuti Ika Widi , Sanjiwani Ida Arimurti , Pramitaresthi I Gusti Ayu
Published: July 2024

The Covid-19 pandemic has caused various problems, one of them is the population sector. The problem of increasing the number of pregnancies, increasing contraceptive dropout rates, and the risk of Baby Booms in Indonesia has made the government recommend that reproductive age couples comply with the use of contraception during the Covid-19 pandemic. The implementation of the Covid-19 prevention protocol has made it difficult for contraceptive acceptors to get services. One form of contraception that requires repeat visits to health workers is injectable contraceptives. Compliance with the use of injectable contraception is realized through the accuracy of the acceptor in re-injecting according to the schedule. Husband's support is one of the factors that can affect adherence to the use of injectable contraceptives. This study aims to determine the relationship between husband's support and adherence to injecting contraceptive use. This research is a correlative analytic study using a cross sectional approach. Research respondents as many as 50 people obtained through non-probability sampling with purposive sampling technique. The instruments used were husband's support questionnaire and re-injection visit card. Data analysis using Chi-square test. The results showed that there was a significant relationship between husband's support and adherence to injecting contraceptive use (p = 0.000; OR = 29.3; 95% CI 6.2 - 138.781). Acceptors who received support from their husbands had 29,3 times more risk of being obedient in using injectable contraception than acceptors who did not receive support from their husbands. This research expects the need for husband involvement in every reproductive health planning of each family member.
Edukasi Media Audiovisual Meningkatkan Kesiapsiagaan Siswa dalam Menghadapi Bencana Gempa Bumi
Authors: Agus Narayana I Gede , Sukarja I Made , Sukawana I Wayan , Juniari Ni Made
Published: July 2024

As many as 75 percent of schools in Indonesia are located in disaster risk areas that threaten the safety of school children. The high number of victims in school children is influenced by the lack of child preparedness in dealing with disasters. The purpose of this study was to determine the effect of audiovisual media education on the preparedness of elementary school students in dealing with earthquake disasters. The type of research is Pre-Experimental Design with a one-group pre-post design. A sample of 30 students in grades IV and V was taken using a simple random technique. Preparedness data was measured using a questionnaire set by LIPI/ UNESCO/ ISDR in 2006. The results showed that the preparedness of elementary school children before the intervention was given, only 36.7% of students had preparedness with the category of being ready and very prepared in dealing with disasters. After being given education with audiovisual media, most of the students (100%) have preparedness and are very ready to face an earth disaster. The results of the Wilcoxon test got a p-value = 0.00 (alpha = 0.05), so it was concluded that the provision of audiovisual media education significantly increased student preparedness in dealing with earthquake disasters in SD Negeri 1 Lagi Gianyar students. Based on the results of this study, it is recommended for school principals to provide audiovisual media education using existing videos as an effort to increase student preparedness in dealing with earthquake natural disasters in elementary school students.
Gambaran Upaya Pencegahan Anemia pada Ibu Hamil
Authors: Erryca Putu , Suratiah Suratiah , Surinati Dewa Ayu Ketut
Published: July 2024

Anemia in pregnant women can increase the risk of premature birth, maternal and child mortality, and infectious diseases. Efforts to prevent anemia in pregnant women launched by the government are adherence to taking blood-added tablets, conducting Hb checks, conducting antenatal care checks and increasing knowledge of pregnant women about anemia. The purpose of this study was to determine the description of anemia prevention efforts in pregnant women in the Work Area of Sukawati Community Health Center I in 2022. This research was quantitative research with descriptive research design and cross sectional approach. The number of samples as many as 41 pregnant women were selected using a non-probability sampling technique with purposive sampling and the data collection instrument used was a questionnaire. The results showed that efforts to prevent anemia in pregnant women by complying with taking iron tablets found that most of them were in the sufficient category as many as 20 people (48.8%), by conducting a Hb examination most of them were in the sufficient category as many as 25 people (61.0%), by conducting antenatal care examination, most of them were in the good category as many as 31 people (75.6%) and by increasing the knowledge of pregnant women about anemia was mostly in the poor category, namely 23 people (56.1%). Therefore, the conclusion to encourage the dissemination of information about anemia and prevention of anemia in pregnancy to pregnant women through classes for pregnant women or counseling during pregnancy check-ups.
Hubungan Sedentary Lifestyle dengan Kejadian Obesitas pada Remaja Selama Masa Pandemi Covid-19
Authors: Wardani Putu Awik Sirna , Suyasa I Gede Putu Darma , Wulandari Idah Ayu
Published: July 2024

During the pandemic, teenagers are required to stay at home and limit their physical activity. Low levels of physical activity and the tendency to stay silent without doing physical activities, which is called a sedentary lifestyle.This study aims to determine the correlation between sedentary lifestyle and obesity among adolescents during Covid 19 pandemic. This study employed correlative analytic design with cross-sectional approach. The population of this study were 1467 students at SMA Negeri 4 Denpasar. There were 285 respondents recruited as sample of this study which were selected through proportional stratified random sampling. The data were collected by using questionnaire and analysed by using Spearman Rho test. From 285 respondents there were 39.6% of the respondents were male and 60.4% of respondents were female. 45.3% of the respondents were 16 years old. The finding showed that 9.8% of respondents experienced obesity and 3.5% of respondents experienced moderate obesity. In addition, the majority of respondents (37.5%) had a tendency to adopt a sedentary lifestyle, 43.5% of respondents had moderate physical activity and 18.9% of respondents had high activity. There was a correlation between correlation between sedentary lifestyle and obesity among adolescents during Covid 19 pandemic (p-value =0.05 r = -0.057). The students are expected to do physical activity at home during Covid 19 pandemic. Schools are advised to provide sports field for students and facilitate canteen staffs to attend training or seminars on nutrition, so that students could do optimal sports activities and their nutritional status is balance.
Hubungan Tingkat Stres dengan Gejala Gastritis Mahasiswa Tingkat IV
Authors: Saraswati Putu Adinda , Suyasa I Gede Putu Darma , Wulandari Idah Ayu
Published: July 2024

Stress can affect a person's diet and rest time. This results in hormonal changes in the body and an increase in stomach acid which can gastritis symptoms. Fourth-year Bachelor of Nursing students in ITEKES Bali have a fairly large study load such as participating in laboratory practices, BTCLS training and completing thesis so they are easy to experience stress. This study aims to analyze the relationship between stress levels and gastritis symptoms Fourth-year Bachelor of Nursing students in ITEKES Bali. This study employed a correlative analytic research design with a cross-sectional approach. The population of this study was the fourth-year Bachelor of Nursing students in ITEKES Bali. Total sampling was employed in this study, in which 189 respondents were involved in this study. Data were collected by using the Kessler Psychological Distress Scale (K10) and gastritis symptom questionnaire and analyzed with Pearson Correlation. The study was conducted on 21 February 2022. Among the 189 respondents, the majority were women (85.2%) and aged 21 years old (56.6%). The results showed that 32 respondents (16.9%) did not experience any stress, 47 respondents (24.9%) experienced mild stress, 67 respondents (35.4%) experienced moderate stress, and 43 respondents (22, 8%) experienced severe stress. 113 respondents (59.8%) experienced gastritis symptoms and 76 respondents (40.2%) did not experience gastritis symptoms. There is significant correlation between stress levels and gastritis symptoms of fourth-year Bachelor of Nursing students in ITEKES Bali (r=0.455, n=189, p= 0.001).
Hubungan Penggunaan Gadget dengan Risiko Masalah Perkembangan Psikososial pada Anak Prasekolah
Authors: Veniawati Kadek Linda , Labir I Ketut , Sulisnadewi N.L.K.
Published: July 2024

The use of technology in the current era of globalization is getting faster, one of the most widely used technologies is gadgets which are one of the media for communicating with the aim of facilitating human communication activities. However, along with the development of the era, the use of gadgets has become one of the basic human needs so that there are many negative impacts caused by using gadgets because they cannot use gadgets properly. One of the negative impacts caused by the use of gadgets is the risk of psychosocial development problems. The purpose of this study was to determine the relationship of the history of gadget use with the risk of psychosocial development problems in preschool children in Jagaraga Village. This research method is correlational which is quantitative. The subject approach model used is cross sectional. The sampling technique used in sampling is non-probability sampling with purposive sampling, namely 97 respondents. Collecting data using a questionnaire technique. Pearson's statistical test obtained a p on the intensity of gadget use with the risk of psychosocial development problems, which is 0.001, then Ho is rejected and Ha is accepted, meaning there is a significant or correlated relationship. this states that there is a relationship between a history of gadget use and the risk of psychosocial development problems in preschool children in Jagaraga Village, Buleleng Regency.
Hubungan Tingkat pendidikan dan Pendapatan Keluarga dengan Kesiapsiagaan Ibu Hamil dan Keluarga Menghadapi Erupsi Gunung Agung
Authors: Efendi Dian Octaviana Rasta , Runiari Nengah , Ruspawan I Dewa Made
Published: July 2024

The lack of preparedness of pregnant women and their families in dealing with disasters is one of the causes of delays in making decisions when facing disasters, especially the eruption of Mount Agung. Factors that affect preparedness include education levels and family income. This study aims to determine the association between education level and family income with the preparedness of pregnant women and families to face the eruption of Mount Agung in the working area of the Selat Public Health Center. The research method in this study was quantitative with a correlational analytical design using a cross-sectional approach. The sampling technique used purposive sampling of as many as 64 people. Collecting data using primary data with a questionnaire sheet. The results showed that most of the pregnant women with a junior high school education level, namely 21 people (32.8%), the family income of pregnant women was almost balanced with an income of IDR 2,500,000, i.e. as many as 35 families (54.7%), and Most of the preparedness of pregnant women to face the eruption of Mount Agung was in the moderate category, namely 24 people (37.5%). The results of the Spearman test show that the level of education (p value = 0.000) (α = 0.05) and family income (p value = 0.058) ( = 0.05), it can be concluded that there is a significant association between the level of education and the preparedness of pregnant women facing the eruption of Mount Agung, but there is no significant association between family income and the preparedness of pregnant women facing the eruption of Mount Agung in the Working Area of the Selat Public Health Center.
Pengaruh Akupresur pada Titik SP 8 dan SP 10 terhadap Intensitas Nyeri Remaja yang Mengalami Dismenore
Authors: Linda Gayatri Ni Luh Putu , Ruspawan Dewa Made , Hartati Ni Nyoman
Published: July 2024

Dysmenorrhea is a gynecological complaint due to an imbalance of the hormone progesterone in the blood, causing pain. Adolescent girls who experience menarche have some disturbances of cramps, pain and discomfort associated with menstruation which is called dysmenorrhea and most adolescents experience varying levels of cramps, pain due to an imbalance of the hormone progesterone in the blood resulting in pain. One of the factors that cause dysmenorrhea is stress which can interfere with the work of the endocrine system, so that it can cause irregular menstruation and cause pain during menstruation. This study aims to determine the effect of acupressure at points SP 8 and SP 10 on the pain intensity of -adolescents who experience dysmenorrhea at the Department of Nursing, Poltekkes, Ministry of Health, Denpasar in 2022. This type of research was pre-experimental with a pre-post-test design in one group (one group pre-test). -post test design) using purposive sampling technique. The total population in the study was 43 people. The number of samples is 39 people. Data was collected using the NRS measurement sheet. The results showed that there was a significant decrease in the dysmenorrhea pain scale after being given acupressure at the SP 8 and SP 10 points with p-value = 0.000 (0.05), this means that Ha is accepted so that there is an influence of SP 8 and SP 10 acupressure points on the pain intensity of adolescents with dysmenorrhea.
Hubungan Penggunaan Gadget Saat Pandemi Covid-19 dengan Ketajaman Penglihatan Siswa
Authors: Suntari Ni Luh Putu Yunianti , Saraswati Gusti Ayu Putri Diah , Ida Erni Sipahutar
Published: July 2024

The Covid-19 pandemic in which all countries limit activities that require gathering togothet. So that more communication and meetings are caried out in cyberspace. Many fields are forced to carry out activities online. One of those affected is learning in schools which can no longer be carried out in school building. Online learning directs student to learn through gadgets, such as smartphones, tablets, computer or laptops. The use of gadgets during the Covid-19 pandemic increased dramatically among junior high school students. The use of the gadgets, with duration, frequency, position, and lighting intensity certainly has an impact on visual acuity in children. This study aims to determine the relationship between the use of gadgets and visual acuity during the Covid-19 pandemic in students. The type of research is non-experimental with correlation design and cross sectional design. The sample in this study amounted to 180 people using a probability sampling technique, namely simple random sampling. Data collection uses a questionnaires about the duration of using the gadget via Google Form in WhatsApp and offline data collection. Visual acuity was measured using the Snellen Chart. The results showed that the most age of respondents was 14 years (74.4%), the most gender was male (63,3%), the use of gadgets was classified as always (41,7%), and visual acuity was classified as normal (85,6%). Hypothesis testing using Spearman rank with α = 0.05. There is relationship between the use of gadgets and visual acuity in VIII grade class student with value of p=0,003. The value of r=0,525 shows a strong correlation between gadgets use and the visual acuity of students. Respondents are expected to know the impact of using the wrong gadget, so as not to damage vision health, their eyesight.
Penerapan Buerger Allen Exercise terhadap Nilai Capillary Refill Time (CRT) pada Klien Diabetes Melitus Tipe 2
Authors: Saputri Silvia , Minarningtyas Asih , Puspitasari Indah
Published: July 2024

Peripheral artery disease is more common in people with diabetes. This chronic complication leads to disruption of peripheral blood vessel flow, thus raising the problem of the ineffectiveness of peripherial tissue perfusion Epidemiological evidence suggests a link between diabetes mellitus and an increased prevalence of perifer arterial disease. Capillary refill time (CRT) is performed quickly on the base area of the nail to monitor dehydration and the amount of blood flow to the tissue.  Objectives The study of this case study to obtain an overview of the Buerger Allen Exercise Movement on Capillary Refill Time (CRT) values in patients with type 2 diabetes. Research design used with a case study approach (single case) by expressing the results of observations and documentation on the value of Capilarry Refill Time after the client performed the Buerger Allen Exercise. Subject in this case study there are 5 patients with diabetes mellitus type 2 who do not have foot injuries and are willing to do buerger movement allen exercise in the work area of UPTD Puskesmas Bekasi Jaya. After the client performed the Buerger Allen exercise for 6 days in a row for 18 minutes each day, the result of the change occurred before and after the Buerker Allen exercise, the capillary refill time was shortened in the type 2 diabetes client. For patients with type 2 diabetes mellitus can perform buerger allen exercise independently and effectively against the effectiveness of peripheral tissue perfusion showing changes in capillary refill time values. (CRT).
Gambaran Kejadian Ikutan Pasca Imunisasi (KIPI) Covid-19 pada Individu dengan Komorbid Diabetes Mellitus
Authors: Astuti Zulmah , Hidayat Faried Rahman , Ericsya Awang Dharma
Published: July 2024

Patients with diabetes mellitus have a fairly high risk of worsening their condition when experiencing Covid-19. This is because individuals are more susceptible to exposure to streptococcal infections, which cause pneumonia, which is a serious complication of respiratory tract problems when exposed to Covid-19. To reduce the impact of these complications, a strategy is needed to increase the immunity of individuals with comorbid diabetes mellitus through the Covid-19 vaccination. The implementation of this vaccination can give a different response to each individual recipient and depends on many factors, including the presence of a previous disease such as diabetes mellitus. The purpose of this study was to get an overview of Covid-19 post-immunization follow-up events (AEFI) in individuals with comorbid diabetes mellitus. This research method is cross-sectional with a purposive sampling technique. The study was conducted on 299 adult respondents who had comorbid diabetes mellitus and received the Covid-19 vaccination. The results of the study obtained data showed that as many as 65 (11,2%) respondents reported not having AEFI symptoms; local symptoms experienced by respondents were swelling (n. 3; 0,5%) and redness at the injection site (n. 1; 0,2%); systemic symptoms experienced by respondents were cramps or muscle pain (n. 104; 17,9%); dizziness (n. 100; 17,2%); fever (n. 99; 17,1%); and drowsiness (n. 93; 16,0%). The degree of AEFI in respondents who had mild symptoms was 93 (16,04%), and moderate symptoms were 422 (72,76%). None of the respondents experienced severe symptoms. Based on these results, it was concluded that the most frequent symptoms were moderate symptoms and systemic symptoms. Even though no severe symptoms are experienced, individual preparation is needed before getting the vaccine to reduce the symptoms of AEFI.