bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating the effect of medical honey and stapler on skin graft fixation in burn wounds: A Randomized clinical Trial
Authors:   Department of Pharmacology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Ahangar Nematollah , Pourebrahimi Amirhossein ,   Medical Student, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Bagheri Toolaroud Parissa ,   Health Information Management Research Center, Kashan University of Medical Sciences, Kashan, Iran., Jarrahi Alale ,   Medical Student, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Ghaffari Mohammad Ebrahim ,   Dental Sciences Research Center, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran., Esmailzadeh Mojdeh ,   Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran., Feizkhah Alireza ,   Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran., Mobayen Mohammadreza ,   Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Published: November 2023

Background One of the applications of honey is in wound healing. A stapler normally connects the skin graft to the underlying bed. Due to its high cost and lack of production in Iran, and causing physical damage to the tissue, an alternative method is needed. Objective This study aims to compare the effects of using medical honey and staplers for skin graft fixation in patients with burn wounds in the north of Iran. Methods In this clinical trial, 80 patients with deep second-degree and third-degree burns less than 40% of total body surface area were included and were randomly divided into two groups of honey (n=40) and stapler (n=40). Demographic information and the percentage of burns were extracted from patients’ medical files. The graft rejection, number of hospitalization days, grafted skin displacement, graft contracture, pain severity, existence of edema or hematoma, itching severity, and infection after grafting were investigated and recorded. Results Of 80 patients, 34 were male (42.5%) and 46 were female (57.5%). The mean age of the patients was 39.29±15.42 years. A significant difference was observed in the mean number of hospitalization days after grafting (P<0.001), incidence of infection, hematoma, edema, and severity of pain and itching (P<0.001), which were lower in the honey group. The graft contracture rate was lower in the stapler group (P<0.001). Graft rejection was not observed in any groups. Conclusion The use of medical honey for skin graft fixation reduces the duration of hospitalization and adverse effects such as pain, itching, edema, hematoma, and infection compared to staplers. This method is as efficient as the routine treatment.
Sustainability Life Cycle Assessment of Household Food Waste Management in Urban Areas
Authors:   Department of Public Health, Faculty of Health Sciences, Universitas Esa Unggul, Jakarta, Indonesia., Kusumaningtiar Devi Angeliana , Vionalita Gisely ,   Department of Public Health, Faculty of Health Sciences, Universitas Esa Unggul, Jakarta, Indonesia., Swamilaksita Prita Dhyani ,   Department of Nutrition Science, Faculty of Health Sciences, Universitas Esa Unggul, Jakarta, Indonesia.
Published: November 2023

Background: Food waste is a severe problem, and Indonesia is the world’s second-largest producer of food waste. A limited waste management system will decrease environmental quality, such as air, water, and soil pollution. So far, the waste management system is limited to reducing waste generation. The life cycle assessment is a method to analyze environmental aspects or environmental impacts at all stages in a resource’s life cycle, from the initial process of raw materials to disposal. This study aims to analyze the environmental impact and provide waste management policies to obtain sustainable household waste management and environmental sustainability. Methods: The study design used in this research is cross-sectional by conducting direct observations and interviews at the Waste Bank. Interviews were conducted to identify more in-depth findings about waste management problems and the characteristics of respondents and waste characteristics. Observations were made to calculate waste generation that refers to Indonesian national standard methods of sample collection and measurement of urban waste generation and composition (SNI 19-3694-1994.) The sampling technique was carried out by the total sampling method, resulting in 100 households. Results: The research results with organic waste processing with the black soldier fly method. This method impacts global warming, acidification, eutrophication, and ozone depletion. Of the four elements that produce the most negligible impact is the impact of global warming of 0.281 kg CO2 eq compared to the other effects. Conclusion: BSF processing can reduce environmental impacts, especially global warming. Meanwhile, education affects people’s behavior in generating food waste; therefore, there are policy recommendations for Waste Bank stakeholders in processing food waste.
ANALISIS KEMAMPUAN LITERASI MATEMATIS SISWA MATERI MATRIKS MENGGUNAKAN MIND MAPPING DI SMA NEGERI 2 TRENGGALEK
Authors: Fuad Alinatul , Ummu Sholihah
Published: November 2023

Latar belakang penelitian dalam skripsi ini adalah rendahnya kemampuan literasi matematis siswa berdasarkan hasil survei yang dilakukan oleh PISA, karena rendahnya minat baca siswa dan kemampuan guru dalam metode pembelajaran matematika. Literasi matematis adalah kemampuan individu untuk merumuskan, menerapkan, memecahkan, dan menafsirkan matematika dalam berbagai konteks dengan menggunakan konsep, prinsip, prosedur, dan fakta untuk mendeskripsikan hingga memprediksi suatu fenomena. Dalam hal ini peneliti menjelaskan bagaimana kemampuan literasi matematis siswa pada materi matriks menggunakan Mind Mapping. Berdasarkan latar belakang diatas, fokus dalam penelitian ini adalah untuk mengetahui kemampuan literasi matematis siswa di kelas XI MIPA 3 SMA Negeri 2 Trenggalek pada materi matriks menggunakan Mind Mapping. Adapun yang menjadi tujuan penelitian ini adalah untuk menganalisis kemampuan literasi matematis siswa di kelas XI MIPA 3 SMA Negeri 2 Trenggalek pada materi matriks menggunakan Mind Mapping.Penelitian ini menggunakan pendekatan kualitatif dan menggunakan jenis penelitian studi kasus. Metode pengumpulan data menggunakan observasi, tes dan wawancara. Teknik analisis data menggunakan reduksi data, penyajian data dan penarikan kesimpulan. Sedangkan pengecekan keabsahan temuan menggunakan ketekunan pengamatan, triangulasi (teknik) dan menggunakan bahan referensi. Hasil penelitian menunjukkan bahwa kemampuan literasi matematis siswa kelas XI MIPA 3 di SMA Negeri 2 Trenggalek pada materi matriks menggunakan Mind Mapping secara garis besar tergolong sedang, dimana berada pada level 3. Dari 35 siswa kelas XI MIPA 3, terdapat tiga siswa berada pada level di bawah 1, dua siswa berada pada level 5, tiga siswa berada pada level 6 dan lainnya berada pada level 3
KAJIAN SEBARAN SALINITAS DENGAN MODEL HEC-RAS DI DAERAH IRIGASI TAMBAK SEI TERAS KALIMANTAN TENGAH
Authors: Hermawanto Hanny Adityanta
Published: November 2023

This study aims to evaluate the distribution of salinity with a mathematical model to enhance advanced aquaculture cultivation. The Sei Teras Fishpond Irrigation Area is one of the aquaculture development areas of the food security program (Food Estate) influenced by tides. Currently, the technology used is simple, and the availability of seeds and feeds depends on nature. The water quality parameters with a specific threshold are needed as an advanced aquaculture requirement to achieve the production level. Vannamei shrimp, as a development commodity, requires a salinity concentration of 15-25 ppt for optimal growth. This study will evaluate the potential of salinity from alternative schemes of introducing gates and normalization against existing conditions using the HEC-RAS program. This program can resolve water quality models with a hydrodynamic simulation procedure through a series of mathematical equations. The simulation results show that the availability of salinity in the two tidal cycles of the spring tide and neap tide could fulfill around 86.7% for 15 days. The normalization has no significant impact on the availability of salinity against existing conditions. The gate influences the longitudinal distribution pattern of salinity. The salinity value above 19 ppt could reach the upstream of the canal up to ± 7 km, while the existing condition could only reach ± 4 km. Therefore, the expected potential of salinity could be achieved.Keywords: salinity, model simulation, distribution, an alternative scheme
NEW METHOD OF KINETIC MODELING OF ETHYLENE OXIDATION REACTION TO ETHYL ALCOHOL AND ACETALDEHYDE BY HYDROGEN PEROXIDE ON THE PER-FTPhPFe3+OH/Al2O3
Authors:   Acad. M.Nagiev Institute of Catalysis and Inorganic Chemistry Ministry of Science and Education of the Azerbaijan Republic, Mammadova U.V. , Gasanova L.M. ,   Acad. M.Nagiev Institute of Catalysis and Inorganic Chemistry Ministry of Science and Education of the Azerbaijan Republic, Nagiev T.M. ,   Acad. M.Nagiev Institute of Catalysis and Inorganic Chemistry Ministry of Science and Education of the Azerbaijan Republic
Published: November 2023

The process of biomimetic monooxidation of ethylene into ethyl alcohol and acetaldehyde by hydrogen peroxide on the per-FTPhPFe3+OH/Al2O3 bioimitator, which showed high activity and unique resistance to the action of high-active intermediate reaction products was investigated. As a result of studying the kinetic regularities of the selective biomimetic oxidation of ethylene by hydrogen peroxide, a coherent-synchronized nature of the reaction was observed, consisting of two reactions: 1) primary (catalase) and 2) secondary (monooxygenase and peroxidase) reactions. A new approach to the kinetic modeling based on the determinant equation and coherence correlation of catalase-monooxygenase and catalase-peroxidase reactions coherently synchronized with each other was developed. The kinetic model of the process was developed on the basis of the determinant equation, which allows assessing the coherent nature of synchronously flowing reactions both qualitatively and quantitatively. Effective rate constants of catalase, monooxygenase and peroxidase reactions were determined based on this model as well as their effective activation energies were calculated.
АКТУАЛЬНІ АСПЕКТИ ДІЯЛЬНОСТІ ЗАКЛАДІВ, ЩО НАДАЮТЬ ПОСЛУГИ ДОШКІЛЬНОЇ ОСВІТИ, В УМОВАХ ВОЄННОГО СТАНУ В УКРАЇНІ
Authors:   SSI ", Tkachenko Valentyna ,   Institute of Educational Analytics", Dron Tetiana ,   SSI "Institute of Educational Analytics"
Published: November 2023

The article contains the results of the research of the organization of educational activities in preschool education institutions under the martial law in Ukraine during the 2022-2023 academic year. The study was conducted by the State Scientific Institution "Institute of Educational Analytics" in accordance with the Operational Plan of the Ministry of Education and Science of Ukraine for 2023 to study the features of the organization of educational activities in preschool education institutions. The article aims to analyze the survey results from three groups of respondents, including heads of institutions (units) of preschool education, educators, and parents of pupils. A quantitative concept was used for the study, in which a representative sample was drawn, research tools were developed, and statistics on the implementation of educational activities were collected. To conduct the study, the authors used the online survey method using the Google Forms service as the most optimal, and the results were processed and visualized using graphs and diagrams. Among the most relevant aspects of the preschool institutions' activities, the following have been highlighted: the establishment of a safe environment, adaptation of the educational process based on the safety situation in the region, and the needs of participants in the educational process and preschool education institutions (units) to ensure quality performance. Particular attention was focused on providing a safe environment in preschool educational institutions (units), including the provision and preparation of shelters, due to the urgent need to maintain the quality of the educational process during the hostilities. The level of provision of preschool education institutions (units) with teaching staff and technical personnel, as well as the employment of persons from the category of internally displaced persons, was recorded. These research findings are an essential component of a comprehensive set of measures aimed at enhancing the quality of preschool education and will serve as the basis for informed management decisions.
ОСОБЛИВОСТІ ЗАБЕЗПЕЧЕННЯ ПРОЗОРОСТІ ТА ЕФЕКТИВНОСТІ БЮДЖЕТНОГО ФІНАНСУВАННЯ ОСВІТИ В УМОВАХ ВОЄННОГО СТАНУ
Authors:   SSI ", Tereshchenko Hanna ,   Institute of Educational Analytics", Kryshchenko Kyrylo ,   PHEI "Bukovinian University"
Published: November 2023

The article addresses current issues related to ensuring transparency and efficiency of budget financing in the education sector under martial law. The authors analyze approaches to ensuring monitoring and transparency in the use of budget funds, which is particularly important during times when Ukraine is facing challenging circumstances, and the issue of rational allocation of available financial resources becomes critical. The article provides an overview of the amount of budgetary funding for education in Ukraine, which has been reduced since the beginning of russia's large-scale war against Ukraine. It is substantiated that one of the ways to address above-mentioned issues is to ensure transparency and effectiveness in budget financing of education by implementing additional financial control measures, primarily by the Ministry of Education and Science of Ukraine. Furthermore, the authors propose the development of relevant performance indicators for educational institutions with a corresponding correlation to the allocated budget financing. At present, the Ministry of Education and Science of Ukraine's control over the designated and efficient use of targeted subventions at the local level has a number of shortcomings: insufficient methodological quality of data in relevant reports, lack of internal automatic data integrity controls, violation of reporting deadlines by respondents, outdated approach of sending out Excel templates for forms and collecting them on the e-mails of authorized specialists, etc. Insufficient use of modern tools for reporting, and consequently, ineffective control over the allocation and use of targeted funding from the state budget by budget managers, limits the effectiveness of managerial decision-making, creates a constant systemic risk of deteriorating education development at the local level. It is necessary to introduce financial reporting for each educational institution, which will allow for an appropriate analysis of the effectiveness of budget spending. In turn, the process of collecting, processing and disseminating such financial statements of educational institutions requires appropriate automation. Automation of the process will enable the quick and efficient processing of reports and the identification of risk areas. In particular, it is advisable to create an information and analytical system for collecting and analyzing financial reports of educational institutions to provide conditions for making management decisions based on reliable and evidence-based data.
ІНТЕГРАЦІЯ ТИМЧАСОВО ПЕРЕМІЩЕНИХ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ ТА ВНУТРІШНЬО ПЕРЕМІЩЕНИХ ОСІБ У КОНКУРЕНТНЕ СЕРЕДОВИЩЕ РИНКУ ОСВІТНІХ ПОСЛУГ У ПЕРІОД НОВИХ ЗАГРОЗ СОЦІАЛЬНІЙ БЕЗПЕЦІ
Authors:   National University of Water and Environmental Engineering, Mazur Nataliia
Published: November 2023

Higher education in Ukraine has found itself in new realities, and the national market of educational services has obtained completely new features of the competitive environment, which combine the results of integration processes and socio-political factors derived from the martial law. As a result of military actions, temporarily relocated higher education institutions (HEIs) emerged as a special category in the market of educational services. The aim of the paper is to study the problems and needs of temporarily relocated HEIs and internally displaced persons, as participants of the educational process, under their integration into the competitive environment of the educational services market. The author determined that for HEIs a study (degree) programme is the main product presented on the market. The primary indicator of the competitiveness of study programmes is the demand declared by entrants to the first (bachelor's) level of higher education. Trends in the formation of a competitive environment in the market of educational services were analysed based on the results of the admission campaign. It was defined that the tendency for Kyiv and Lviv universities to hold the leading positions in most study programmes was preserved. The article presents a comparative analysis of the dynamics of the main competitiveness indicators for study programmes, being most popular among entrants, in HEIs identified as leaders in terms of the number of applications and in temporarily relocated HEIs. The relocated HEIs are facing a particularly acute problem with filling the licensed number of students. Based on the admission results of 2022, a part of relocated universities enrolled only as many students as to fill the positions funded by the state. Temporarily relocated HEIs and internally displaced research and pedagogical staff need additional social protection tools and special support and assistance in resuming full-fledged activities from host communities, local self-government bodies, the government and international organizations.
Pendampingan Penatalaksanaan Penderita Diabetes Melitus di Paguyuban Diabetes dan Hidup Sehat Kelurahan Darmo Wonokromo Surabaya
Authors: Lestarina Ni Nyoman Wahyu , Kurniawaty Yuni , Dwianto Ignatius Heri , Silalahi Veronica , Djajanti Cicilia Wahju , Nesa Kadek Sistadewi , Diva Natalia Cika
Published: November 2023

ABSTRAK Penyakit DM merupakan penyakit yang dapat menyebabkan banyak komplikasi dan dapat menyebabkan kematian. Paguyuban Diabetes dan Hidup Sehat (PDHS) menjadi salah satu perkumpulan yang terdiri dari orang-orang yang menderita diabetes atau penyakit kronis lain. Permasalahan yang didapatkan pada mitra adalah adanya resiko penderita diabetes mellitus mengalami komplikasi, ketidakpatuhan penderita untuk melakukan pola hidup sehat, dan keputusasaan dalam menjalani kehidupan penyakit dialami. Pendampingan ini dilakukan pada 30 orang dengan diabetes mellitus yang tergabung dalam PDHS yang bertujuan meningkatkan kesehatan, kepatuhan, dan kualitas hidup penderita diabetes. Kegiatan ini dilakukan dengan sosialisasi kegiatan kepada mitra, penerapan insole sepatu, pelatihan strategi koping dan penatalaksanaan diabetes mellitus dengan menggunakan modul patuh DM dan  pendampingan setelah adanya pelatihan. Para penderita DM mengikuti kegiatan dan pelatihan dengan antusias dan baik. Manfaat yang diperoleh yaitu terdapat penurunan kadar gula darah acak penderita DM, peningkatan pengetahuan dan kepatuhan penderita dalam tatalaksana DM serta peningkatan pengetahuan serta ketrampilan dalam strategi koping yang adaptif. Pendampingan penatalaksanaan diabetes melitus diberikan untuk meningkatkan kualitas hidup sehat penderita dan koping yang adaptif. Kata Kunci: Diabetes Melitus, Insole Sepatu, Strategi Koping  ABSTRACT DM is a disease that can cause many complications and even death. The Diabetes and Healthy Living Association (PDHS) is an association consisting of people who suffer from diabetes or other chronic diseases. The problems found in partners are the risk of diabetes mellitus sufferers experiencing complications, the sufferer's non-compliance with adopting a healthy lifestyle, and hopelessness in living the life of the disease experienced. This assistance was carried out for 30 people with diabetes mellitus who are members of PDHS to improve the health, compliance, and quality of life of diabetes sufferers. This activity was carried out by socializing the activity to partners, applying shoe insoles, training on coping strategies, managing diabetes mellitus using the DM compliance module, and mentoring after the training. DM sufferers participated in activities and training enthusiastically and well. The benefits obtained are that there is a decrease in random blood sugar levels in DM sufferers, increased knowledge and compliance of sufferers in DM management, and increased knowledge and skills in adaptive coping strategies. Assistance in managing diabetes mellitus is provided to improve the patient's healthy quality of life and adaptive coping.  Keywords: Diabetes Mellitus, Shoe Insoles, Coping Strategies
منهج القرآن الكريم والسنة النبوية في إدارة الأزمة الاجتماعية (أزمة الإفك) نموذجاً
Authors: El-Moghrabi Reem Ahmad Abdelmajeed , Abd Kadir Kauthar Binti , Mohamed Ahmad Kamel
Published: November 2023

This article attempts to highlight the approach of the Holy Qur’an &Sunnah in managing crises by presenting some models and ways to solve them. This includes the social crisis that the Prophet Muhammad (peace be upon him) was exposed to, which is the crisis of defamation. This was a difficult ordeal, and it was a plot planned by the enemies of Islam and propagated by the hypocrites in order to distort the image of the Prophet. However, the Qur’an revealed the innocence of the honorable and chaste Mother of the Believers, and condemned the people of hypocrisy. The study aims to consolidate the management of social crises, to illustrate the approach of the Holy Qur’an, and to present new material that highlights the greatness of the Qur’an and its ability to address all human crises. This will be done by consulting ancient and modern interpretations of the Qur’an, as well as modern social crisis management science books and and the prophetic approach by referring to the books of hadith. The study included the results drawn from this crisis, such as the fact that falsification, in its concept in the current era and in the dictionaries of the ancient Arabic language, leads to the occurrence of crises and destroys society. The study also concluded that rumours have harmful consequences. The crisis of defamation also has reasons that led to its eruption, goals, and stages it went through. The truth emerged and falsehood was destroyed with the revelation of the Noble Qur’an to the innocence of Aisha, may God be pleased with her. The researcher recommended the necessity of directing Quranic & Sunnah studies to all issues affecting the individual and society. They also emphasized the need for crisis management and the study of many of the problems of the current era and the search for solutions to these crises through the Holy Qur’an. The researcher proposed that these studies be conducted as objective scientific Qur’anic studies and through the prophetic Sunnah and studying it as an objective prophetic study.
Editorial: Transformative Impact of Artificial Intelligence on Higher Education
Authors: Sirkeci Ibrahim , Lo Lan
Published: November 2023

Welcome to this second issue of Transnational Education Review (TER) in 2023. In this editorial, we also would like to reflect on an emerging phenomenon: Artificial Intelligence (AI) and its impact on higher education. We would like to invite colleagues to submit their research, commentaries, debates and viewpoints in coming issues to share views and shape the agenda regarding AI and the future of learning and teaching in higher education. In this second issue of Transnational Education Review (TER) in 2023, we have a set of interesting articles from around the world. In the opening article, Görsev Sönmez and Serkan Gürkan examine the perceptions of pre-service teachers regarding the refugee students in the education faculty of a private university in Istanbul, Turkey. Second paper by Emel Kiliç explores the socio-cultural integration of Turkish-speaking migrants in Belgium. As Emel explains migration can be a challenging but rewarding experience, in Belgium, integration courses are available to provide essential support for migrants so that they adapt to their new environment. In Betül Dilara Şeker and Ibrahim Sirkeci’s insightful article, they argue that language proficiency was the most critical variable in education and adaptation to the host culture, and their findings indicate the importance of schools in the acculturation and adaptation of the Syrian refugee students. We hope you will find these contributions useful. Finally, once again, we extend an open invitation to all researchers, practitioners and scholars to join us in this debate with their research, views, comments and reviews.
Crisis carcelaria en el Ecuador desde una perspectiva criminológica: causas, consecuencias y propuestas de intervención
Authors: Morocho Bermeo Erika Filomena , Inga Yanza Julio César
Published: November 2023

Objetivos: El presente artículo tiene como finalidad demostrar la existencia de la crisis carcelaria en el Ecuador, abordada desde el enfoque criminológico para de esta forma comprender las causas, analizar las consecuencias que ha generado y proponer estrategias de intervención efectivas, con el propósito de colaborar en la mejora del sistema de reclusión y la reducción de la violencia y reincidencia delictiva. Metodología: La revisión bibliográfica y documental realizada revela que las causas de la emergencia penitenciaria son múltiples y complejas. Resultados: Entre las principales se encuentran la sobrepoblación penitenciaria, el uso indiscriminado de la prisión preventiva, las precarias condiciones de vida en prisión, la carencia de recursos y personal capacitado, la corrupción, y la violencia tanto entre internos como hacia el personal penitenciario. Conclusiones: Las consecuencias de la crisis carcelaria son evidentes y preocupantes, afecta a la sociedad en su conjunto, al generar inseguridad y desconfianza en la justicia penal. Para abordar esta problemática, se proponen diversas intervenciones basadas en la criminología. Área de estudio general: Derecho. Área de estudio específica: Derecho Procesal.
Kinh nghiệm xây dựng hệ thống cơ sở dữ liệu trích dẫn tạp chí khoa học quốc gia của Thái Lan, Malaixia và bài học cho Việt Nam
Authors: Lê Quốc Hội , Phan Hải , Đặng Trần Thường
Published: November 2023

Bài viết này nghiên cứu hệ thống cơ sở dữ liệu trích dẫn tạp chí khoa học của 2 quốc gia khu vực Đông Nam Á là Thái Lan và Malaixia trên các phương diện từ lịch sử hình thành, cấu trúc hệ thống, mô hình tổ chức đến hoạt xét duyệt tạp chí. Trên cơ sở kinh nghiệm của Thái Lan và Malaixia, bài viết đề xuất một số bài học kinh nghiệm hữu ích đối với Việt Nam trong việc xây dựng hệ thống cơ sở dữ liệu trích dẫn tạp chí khoa học quốc gia (VCI). Cụ thể, VCI cần: một đội ngũ tâm huyết, tận tụy và có chuyên môn; được hỗ trợ nguồn tài chính bền vững; sự độc lập và minh bạch trong hoạt động; nền tảng công nghệ thông tin và kỹ thuật chuẩn hóa, hiện đại; kết nối, hợp tác với các trường đại học, viện nghiên cứu và các sở sở dữ liệu quốc tế.
Pengaruh Model Problem Based Learning (PBL) terhadap Kemampuan Membangun Sikap Mandiri dan Hasil Belajar Siswa Pada Mata Pelajaran PKn Kelas IV SD Negeri 75 Kota Bengkulu
Authors: HARMELIA DENTY , Puspa Djuwita
Published: November 2023

// This study aims to determine the effect of the Problem Based Learning model on the ability to build independent attitudes and student learning outcomes in the fourth grade Pkn Subject SD Negeri 75 Kota Bengkulu. This type of research is the Mix Method. The research samples obtained were students of grade IV A and IV D SD Negeri 75 Bengkulu City, amounting to 38 and 37 students. The research instruments used were questionnaire sheets, interview sheets and test sheets. The research data on the independent attitude showed that the result of t count was 1.746 with a significant level of 5%, namely 0.020 <0.05, meaning that there was an influence of the PBL model on the independent attitude of students in class IV SD Negeri 75 Bengkulu City. In the results of the pretest value in the experimental class and control class, namely t count of 1.528 with a significant level of 5%, namely 0.058> 0.05, it means that there is no influence of the PBL model on the independent attitude of students in class IV SD Negeri 75 Bengkulu City. Whereas the results of the posstest score in the experimental class and control class obtained t count of 3.345 with a significant level of 5%, namely 0.001 <0.05, meaning that there is an effect of the PBL model on the independent attitude of students in class IV SD Negeri 75 Bengkulu City so it can be concluded that PBL model on the ability of independent attitudes and learning outcomes of fourth grade students of SD Negeri 75 Kota Bengkulu.
CROISSANT SUBTITUSI TEPUNG KEDELAI TINGGI ENERGI DAN PROTEIN SEBAGAI ALTERNATIF SNACK UNTUK REMAJA AKHIR : ANALISIS DAYA TERIMA, KANDUNGAN ENERGI DAN PROTEIN
Authors:   Siliwangi University Indonesia, Hartanti Mutia Maryami , Susilowati Prima Endang ,   Siliwangi University Indonesia, Kosnayani Ai Sri ,   Siliwangi University Indonesia
Published: November 2023

Peningkatan pertumbuhan fisik, perkembangan serta tingkat aktivitas tinggi yang dialami oleh remaja mengakibatkan kelompok tersebut menjadi kelompok rentan gizi. Pemenuhan kebutuhan gizi remaja menjadi sangat penting karena akan mempengaruhi pada proses tubuh dan berkembang. Salah satu upaya untuk menambah pemenuhan gizi remaja adalah pemberian makanan padat gizi melalui makanan selingan. Makanan selingan kaya gizi dapat diperoleh dari pengembangan resep makanan berupa modifikasi bahan. Tepung kedelai berpotensi untuk mensubstitusi tepung terigu sebagai bahan pembuatan croissant, karena kandungan gizinya yang lebih baik. Penelitian ini bertujuan untuk mengetahui perbedaan daya terima serta kandungan energi dan protein pada croissant subtitusi tepung kedelai sebagai makanan selingan remaja akhir. Rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap dengan empat perlakuan. Daya terima dilakukan dengan uji organoleptik oleh 5 panelis terlatih dan 15 panelis tidak terlatih. Uji organoleptik meliputi penilaian warna, aroma, tekstur, dan rasa. Analisis statistik daya terima dilakukan menggunakan uji Kruskall wallis. Penentuan formula terpilih dilakukan berdasarkan nilai rata-rata tertinggi pada uji daya terima. Pengujian kandungan energi dan protein formula terpilih dilakukan di SIG Laboratory Bogor. Hasil daya terima croissant pada warna, aroma, tekstur, dan rasa menunjukan tidak ada perbedaan nyata (p>0.05) antara perlakuan. Formula F1 merupakan formula terpilih yang memiliki daya terima tertinggi. Kandungan energi 100 g F1 adalah 490,9 kkal dan protein sebanyak 9,375%. Satu sajian croissant F1 seberat 60 g mengandung energi 294,6 kkal; dan protein 5,6 g. Takaran saji yang dapat memenuhi kebutuhan makanan selingan bagi remaja akhir berdasarkan AKG usia 16-18 tahun adalah satu setengah saji.
PEMANFAATAN TEPUNG TALAS BENENG (Xanthosoma undipes K. koch) PADA PEMBUATAN STIK KEJU SUMBER SERAT
Authors:   Universitas Muhammadiyah Prof. Dr. HAMKA, Fitriyansyah Alif Rahmat , Sofyaningsih Mira ,   Universitas Muhammadiyah Prof. Dr. HAMKA
Published: November 2023

Tepung talas beneng merupakan salah satu produk olahan tepung yang sudah banyak diproduksi di wilayah Banten dan dapat dimanfaatkan dalam pembuatan makanan seperti stik keju. Tujuan penelitian ini adalah memanfaatkan bahan pangan lokal dari tepung talas beneng dalam pembuatan stik keju sebagai alternatif jajanan sumber serat. Parameter yang diamati adalah kapang pada tepung talas beneng, kadar proksimat, dan serat pangan pada stik keju terbaik. Rancangan yang digunakan dalam penelitian ini adalah eksperimen dengan metode rancangan acak lengkap. Terdapat 4 faktor perlakuan yaitu F0 (100% tepung terigu) sebagai kontrol, F1 (50%), F2 (65%), dan F3 (80%). Uji penerimaan konsumen dilakukan terhadap 30 orang panelis tidak terlatih untuk menilai kesukaan terhadap stik keju terhadap indikator warna, aroma, tekstur, rasa, keseluruhan, rasa di mulut, dan sisa rasa. Hasil penelitian menunjukkan bahwa stik keju terbaik terdapat pada F1 (50%). kemudian dilakukan uji normalitas dan uji lanjutan Kruskal-Wallis dengan tingkat signifikansi α=0,05, menunjukkan bahwa terdapat perbedaan yang signifikan pada indikator warna, aroma, dan tekstur stik keju, sedangkan pada indikator stik keju rasa, keseluruhan, rasa di mulut, dan sisa rasa tidak menunjukkan adanya perbedaan yang nyata. Hasil uji proksimat dan serat pangan untuk produk terbaik per 100 g yaitu energi total 440.53 kkal, kadar abu 3.57 g, kadar air 7.06 g, karbohidrat 59.145 g, lemak total 16.61 g, protein 13.615 g, dan serat pangan 9.12 g tergolong dalam kategori kaya serat.
Differential Laws of Left Ventricular Isovolumic Pressure Fall
Authors: Langer SFJ
Published: November 2023

An attempt has been made to test for a reliable method of characterizing the isovolumic left ventricular pressure fall in isolated ejecting hearts by one or two time constants, tau. Alternative nonlinear regression models (three- and four-parametric exponential, logistic, and power function), based upon the common differential law dp(t)/dt = - [p(t)-Ptau]/ tau(t) are compared in isolated ejecting rat, guinea pig, and ferret hearts. Intraventricular pressure fall data are taken from an isovolumic standard interval and from a subinterval of the latter, determined data-dependently by a statistical procedure. Extending the three-parametric exponential fitting function to four-parametric models reduces regression errors by about 20-30 %. No remarkable advantage of a particular four-parametric model over the other was revealed. Enhanced relaxation, induced by isoprenaline, is more sensitively indicated by the asymptotic logistic time constant than by the usual exponential. If early and late parts of the isovolumic pressure fall are discarded by selecting a subinterval of the isovolumic phase, ? remains fairly constant in that central pressure fall region. Physiological considerations point to the logistic model as an advantageous method to cover lusitropic changes by an early and a late tau. Alternatively, identifying a central isovolumic relaxation interval facilitates the calculation of a single ("central") tau; there is no statistical justification in this case to extend the three-parametric exponential further to reduce regression errors.
Model of Visually Evoked Cortical Potentials
Authors: Kremláček J , Kuba M , Holčík J
Published: November 2023

The pattern-reversal (P-VEPs) and the motion-onset (M-VEPs) of visual evoked potentials were modeled by means of three damped oscillators (O1, O2, O3) of identical construction. The O1, assumed to simulate the response of primary visual area (V1), was driven by the firing density of the lateral geniculate nuclei. O1 contributed mainly to the N75 and P100 peaks of the P-VEPs. The O2, driven by the O1 output, mimics the activity of V2, V3a, and MT. It contributed to the negative peak N145 of the P-VEPs or to the N160 in the M-VEPs. The O3 was suggested to model late slow processes probably of an attentive origin. The model parameters were set by optimization to follow the P-VEPs and M-VEPs obtained as a grand average of four young volunteers (PZ - A2 lead). The evoked potentials were described with normalized root mean square error lower than 13 %.
The Effect of an Acute Fat Load on Endothelial Function after Different Dietary Regimens in Young Healthy Volunteers
Authors: Šejda T , Kovář J , Piťha J , Cífková R , Švandová E , Poledne R
Published: November 2023

Attention has recently been focused on endothelial function after a single high-fat meal, i.e. on the anticipated direct atherogenic effect of triglyceride-rich lipoproteins. Our study was designed to investigate the effect of a low-fat diet given for four weeks followed by a high-fat diet for another four weeks. At the end of each dietary period, a non-invasive ultrasound investigation of endothelial function of the brachial artery was performed along with laboratory tests. Endothelial function was measured immediately before the dietary load and after three and six hours in 11 healthy volunteers. The results were expressed as percentage of the changes in artery diameter at rest and during hyperemia; the data were processed using computer technology. When compared to the low-fat regimen, the total cholesterol content rose after the high-fat diet from 4.28 mmol/l to 5.15 mmol/l (p<0.05) in the whole group of volunteers. There was no difference between both dietary regimens in baseline triglycerides. The brachial artery dilatation under basal conditions was 5.26±2.88 mm after the high-fat diet compared with the value of 3.13±3.01 mm (p<0.05) after the low-fat diet. When measured individually endothelial function in the whole group of volunteers in the course of the day, the degree of arterial dilatation after one month on low-fat diet was 3.13±3.0 %, 3.88±2.5 % and 5.23±3.3 % at single measurement. When comparing arterial dilatation at two closest measurements, a non-significant trend, p>0.05 was seen in either case. The following values were obtained after one month on the high-fat diet: 5.26±2.9 %, 4.47±1.7 %, and 6.2±3.6 %; again showing a non-significant trend of p>0.05. In this study, a single high-fat meal at the different dietary regimen did not significantly influence the vasoreactivity of the brachial artery in young volunteers.
Mismatch of Local Blood Flow and Oxidative Metabolism in Stunned Myocardium
Authors: Schwanke U , Heusch G , Schipke JD
Published: November 2023

Myocardial blood flow is spatially heterogeneous, reflecting non-uniform oxygen supply. Also, myocardial oxida-tive metabolism is spatially heterogeneous. The effects of acute ischemia and reperfusion on the rela-tionship between local myocardial blood flow (LMF) and oxi-dative metabolism are still unknown. LMF was measured in isolated, blood-perfused rabbit hearts using colored microspheres and oxidation water labeled with 18O2 (H218O). Three protocols were performed: 18O2-perfusion during normoxia (N; n=7), during early reperfusion (ER; 10 min, n=6), and late reperfusion (LR; 40 min, n=6) following 20 min no-flow ischemia. LMF and local H218O residues were determined within defined myocardial samples (105 ± 15 mg). For interindividual comparison, values were normalized to the mean of the individual experiment and expressed as percentages. LMF ranged from 18 to 193 % (N), 12 to 250 % (ER), and 11 to 180 % (LR). The H218O tissue residue ranged from 63 to 132 % (N), 73 to 142 % (ER) and 32 to 148 % (LR). The correlation between LMF and local oxidative metabolism during N (r=0.77; n=56) was lost in the postischemic heart during ER and LR. LMF during N and ER were only weakly correlated (r=0.24; n=48), whereas LMF during N and LR correlated well (r=0.87; n=48). It is concluded that the heterogeneous LMF pattern at baseline is maintained in the stunned myocardium whereas that of local oxidative metabolism is not. Apart from the established mechanisms underlying myocardial stunning, a mismatch between local flow and oxidative metabolism might also con-tribute.
The Impact of Leadership, Character, and Sanctity of the Congregational Pastor on the Spiritual Growth of the Church Members
Authors: Purnomo Setya Hari , Lontoh Frederich Oscar L , Octavianus Jonathan
Published: November 2023

This study presents the influence of leadership, character, and sanctity of the congregational pastor on the spiritual growth of church members, specifically those attending the Alfa Omega Ketintang Baru Church in Surabaya. The aim of this research is to analyze the relationship between leadership, character, and sanctity of the congregational pastor and the spiritual growth of church members, particularly those attending the Alfa Omega Ketintang Baru Church in Surabaya. The study employs a survey method to collect data on the influence of leadership, character, and sanctity of the congregational pastor on the spiritual growth of church members. The research sample consists of 150 church members of GPdI Alfa Omega Ketintang Baru in Surabaya. Data is gathered through questionnaires and analyzed using linear regression analysis. The results of the analysis indicate a positive correlation between leadership, character, and sanctity of the congregational pastor and the spiritual growth of church members. The research finds that improvements in leadership, character, and sanctity of the congregational pastor are associated with an increase in the spiritual growth of GPdI Alfa Omega Ketintang Baru church members in Surabaya. The results are as follows: When looking at the population, a t-value of 4.321 for leadership, 3.378 for character, and 5.721 for sanctity is obtained, which is significant at a < 0.05 level. This implies that the variables of leadership, character, and sanctity of the congregational pastor significantly influence the spiritual growth of GPdI Alfa Omega Ketintang Baru church members in Surabaya. Future studies could expand the scope of this research by involving more variables that affect the spiritual growth of church members. Additionally, it is essential to conduct evaluations of church programs, collaborate with mission agencies, and implement effective management systems to enhance the spiritual quality of Christians, the analysis also yielded an R-squared value (Coefficient of Determination) of 0.790 or 79.0%. This means that the contribution of the variables Leadership, Character, and Sanctity of the Congregation's Leader in shaping the Spiritual Growth of the GPdI Alfa Omega Congregation in Ketintang Baru, Surabaya, is 79.0%, while the remaining 21% is influenced by other factors outside the research model.
Adaptivity as a key feature of mobile maps in the digital era
Authors: Reichenbacher Tumasch , Bartling Mona
Published: November 2023

Mobile maps are an important tool for mastering modern digital life. In this paper, we outline our perspective on the challenges and opportunities associated with designing adaptive mobile maps that are useful, usable, and accessible to a wide range of users in different contexts. If we claim for adaptive mobile maps to be successful, we need to expand our understanding of map use context, including the physical and digital spaces, user behavior, and individual differences. We identify key challenges, such as the scarcity of knowledge about mobile map use behavior, the need for effective adaptation methods and strategies, user acceptance of adaptive maps, and issues related to control, privacy, trust, and transparency. We finally suggest research opportunities, such as studying mobile map usage, employing AI-based adaptation methods, leveraging the power of visual communication through maps, and ensuring user acceptance through user control and privacy.
Exploring the potential mechanisms of Tongmai Jiangtang capsules in treating diabetic nephropathy through multi-dimensional data
Authors: Liu Yi , Cui Xin , Zhang Xuming , Xie Zhuoting , Wang Weili , Xi Junyu , Xie Yanming
Published: November 2023

Background

Diabetic nephropathy (DN) is a prevalent and debilitating disease that represents the leading cause of chronic kidney disease which imposes public health challenges Tongmai Jiangtang capsule (TMJT) is commonly used for the treatment of DN, albeit its underlying mechanisms of action are still elusive.

Methods

This study retrieved databases to identify the components and collect the targets of TMJT and DN. Target networks were constructed to screen the core components and targets. Samples from the GEO database were utilized to perform analyses of targets and immune cells and obtain significantly differentially expressed core genes (SDECGs). We also selected a machine learning model to screen the feature genes and construct a nomogram. Furthermore, molecular docking, another GEO dataset, and Mendelian randomization (MR) were utilized for preliminary validation. We subsequently clustered the samples based on SDECG expression and consensus clustering and performed analyses between the clusters. Finally, we scored the SDECG score and analyzed the differences between clusters.

Results

This study identified 13 SDECGs between DN and normal groups which positively regulated immune cells. We also identified five feature genes (CD40LG, EP300, IL1B, GAPDH, and EGF) which were used to construct a nomogram. MR analysis indicated a causal link between elevated IL1B levels and an increased risk of DN. Clustering analysis divided DN samples into four groups, among which, C1 and CI were mainly highly expressed and most immune cells were up-regulated. C2 and CII were the opposite. Finally, we found significant differences in SDECG scores between C1 and C2, CI and CII, respectively.

Conclusion

TMJT may alleviate DN via core components (e.g. Denudatin B, hancinol, hirudinoidine A) targeting SDECGs (e.g. SRC, EGF, GAPDH), with the involvement of feature genes and modulation of immune and inflammation-related pathways. These findings have potential implications for clinical practice and future investigations.
Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control
Authors: Stenlid Rasmus , Cerenius Sara Y. , Wen Quan , Aydin Banu Küçükemre , Manell Hannes , Chowdhury Azazul , Kristinsson Hjalti , Ciba Iris , Gjessing Erik S. , Mörwald Katharina , Gomahr Julian , Heu Verena , Weghuber Daniel , Forslund Anders , Bergsten Peter
Published: November 2023

Background

GLP-1 receptor agonists (GLP-1RA) are increasingly used to treat adolescent obesity. However, the effect on endogenous GLP-1 secretory patterns following treatment in adolescents is unknown. The GLP-1RA exenatide was shown to significantly lower BMI and 2-hour glucose in adolescents with obesity, in the placebo-controlled, randomized controlled trial Combat-JUDO. The aim of this study was to evaluate effects of weekly injections of 2 mg exenatide extended release on secretory patterns of endogenous hormones during OGTT.

Subjects and Measurements

This study was a pre-planned sub-study of the Combat-JUDO trial, set at the Pediatric clinic at Uppsala University Hospital, Sweden and Paracelsus Medical University, Austria. 44 adolescents with obesity were included and randomized 1:1 to treatment:placebo. 19 patients in the treatment group and 18 in the placebo group completed the trial. Before and after treatment, GLP-1, glucose, insulin, glucagon and glicentin levels were measured during OGTT; DPP-4 and proinsulin were measured at fasting. A per-protocol approach was used in the analyses.

Results

Exenatide treatment did not affect GLP-1 levels during OGTT. Treatment significantly lowered DPP-4, proinsulin and the proinsulin-to-insulin ratio at fasting, increased glicentin levels but did not affect insulin, C-peptide or glucagon levels during OGTT.

Conclusion

Weekly s.c. injections with 2 mg of exenatide maintains endogenous total GLP-1 levels and lowers circulating DPP-4 levels. This adds an argument in favor of using exenatide in the treatment of pediatric obesity.

Clinical trial registration

clinicaltrials.gov, identifier NCT02794402