bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring Internal and External Interactions for Semi‐Structured Multivariate Attributes in Job‐Resume Matching
Authors: Shao Taihua , Song Chengyu , Zheng Jianming , Cai Fei , Chen Honghui
Published: April 2023

Job‐resume matching (JRM) is the core of online recruitment services for predicting the matching degree between a job post and a resume. Most of the existing methods for JRM achieve a promising performance by simplifying this task as a matching between the free‐text attributes in the job post and the resume. However, they neglect the contributions of the semistructured multivariate attributes such as education and salary, which will result in an unsuccessful prediction. To address this issue, we propose a novel approach to comprehensively explore the Internal and EXternal InTeractions for semistructured multivariate attributes in JRM, i.e., InEXIT. In detail, we first encode the key and the value of each attribute as well as its source into the same semantic space. Next, to explore the complex relationships among the multivariate attributes, we propose to hierarchically model the internal interactions among the multivariate attributes inside the job post and the resume, as well as the external interactions between the job post and the resume. In particular, a stepwise fusion mechanism is designed to respectively integrate the key embeddings and the source embeddings into the value embeddings so as to clearly indicate the key and the source of the value. Finally, we employ an aggregation matching layer to predict the matching degree. We quantify the improvements of InEXIT against the competitive baselines on a real‐world dataset, showing a general improvement of 4.28%, 4.10%, and 3.56% over the state‐of‐the‐art baseline in terms of AUC, accuracy, and F1 score, respectively.
Metformin-Induced Generalized Bullous Fixed-Drug Eruption with a Positive Dechallenge-Rechallenge Test: A Case Report and Literature Review
Authors: Abtahi-Naeini Bahareh , Momen Tooba , Amiri Rezvan , Rajabi Parvin , Rastegarnasab Fereshte
Published: April 2023

Metformin is a commonly used medication in diabetic patients. It can cause different complications including cutaneous adverse reactions. Metformin-induced fixed-drug eruption (FDE) has been reported in limited cases. Due to the popularity of metformin, clinicians need to be aware of uncommon drug reactions for proper diagnosis and treatment. Herein, we report a 43-year-old man with generalized bullous lesions with a positive dechallenge-rechallenge test diagnosed as metformin-induced generalized bullous fixed-drug eruption. Metformin dosage was stopped and lesions were treated with topical clobetasol propionate and oral prednisolone and cyclosporine-A. After a 6-month follow-up, he was well without any relapsing episodes.
circRNA_17725 Promotes Macrophage Polarization towards M2 by Targeting FAM46C to Alleviate Arthritis
Authors: Yang Chunjuan , Ni Biao , Li Chaoran , Sun Wenchang , Wang Zhangxue , Wang Hui , Hou Xinyue , Yan Shushan , Wang Xiaodong , Xu Donghua
Published: April 2023

Accumulating studies have implicated that circular RNAs (circRNAs) play vital roles in the pathogenesis of rheumatoid arthritis (RA). Dysregulation of macrophage polarization leads to immune homeostatic imbalance in RA. However, the altering effects and mechanisms of circRNAs on macrophages polarization and immune homeostatic balance remain largely unclear. We aimed to investigate the potential role of circRNA_17725 in RA. The high-throughput sequence was performed to identify the dysregulated circRNAs in RA. We confirmed the data by CCK-8, EdU, and Annexin V/PI staining to elucidate the proliferation and apoptosis. The expressions of M1/M2-associated markers were confirmed using real-time PCR and flow cytometry analysis. Luciferase reporter assay and RNA Binding Protein Immunoprecipitation (RIP) were used to demonstrate the underlying mechanism of circRNA_17725. The altering effect of circRNA_17725 on macrophages in vivo was evaluated using collagen-induced arthritis (CIA) mouse model. circRNA_17725 was demonstrated to be downregulated in peripheral blood mononuclear cells and CD14+ monocytes from RA cases in contrast to healthy controls. The negative association between circRNA_17725 and the disease activity indexes (CRP, ESR, and DAS28) was observed, suggesting a vital role of circRNA_17725 in RA disease activity. Besides, after a coexpression analysis based on high-input sequencing and the bioinformatics analysis in MiRanda and TargetScan databases, a circRNA_17725-miR-4668-5p-FAM46C competing endogenous RNA (ceRNA) network was hypothesized. A series of cytology experiments in vitro have implicated that circRNA_17725 could inhibit the proliferation but enhance the apoptosis of macrophages. Decreased expression of TNF-α, IL-1β, and MMP-9 were observed in the supernatant of circRNA_17725-overexpressed Raw264.7 macrophages, implicating the inhibitory effect of circRNA_17725 on macrophage inflammatory mediators. Furthermore, circRNA_17725 could promote macrophage polarization towards M2 by targeting miR-4668-5p/FAM46C as a miRNA sponge. Additionally, circRNA_17725-overexpressed macrophages alleviated arthritis and protected against joint injuries and bone destruction by inducing macrophage polarization towards M2 in collagen-induced arthritis (CIA) mice. This study has suggested that circRNA_17725 regulated macrophage proliferation, apoptosis, inflammation, and polarization by sponging miR-4668-5p and upregulating FAM46C in RA.
Application of Microcontroller-Based Multipath Servos in Industrial Robot Control Systems
Authors: Hu Ruiming
Published: April 2023

In recent years, nanotechnology has continued to develop, especially the use of nanomaterials in various fields. Microcontroller is the most typical embedded system at this stage. With the development of science and technology, microcontroller has been widely used in people’s production life. A simple and practical multiservo controller can be built by using microcontroller and LED control chip PCA9685, which can realize at least 16 channels of servo control. In this paper, the control program of multichannel actuator is designed in detail, and the speed regulation of multichannel actuator is studied, which is applied to the industrial robot system driven by actuator. Nanomaterials, as new materials with various unique properties, have great application prospects, and this paper investigates the extension of nanomaterials in the field of robotic systems.
Supplementary Figure 1 from Nitric Oxide Boosts Chemoimmunotherapy via Inhibition of Acid Sphingomyelinase in a Mouse Model of Melanoma
Authors: Perrotta Cristiana , Bizzozero Laura , Falcone Sestina , Rovere-Querini Patrizia , Prinetti Alessandro , Schuchman Edward H. , Sonnino Sandro , Manfredi Angelo A. , Clementi Emilio
Published: April 2023

Supplementary Figure 1 from Nitric Oxide Boosts Chemoimmunotherapy via Inhibition of Acid Sphingomyelinase in a Mouse Model of Melanoma
Supplementary Tables 1-2 from Chimeric NKG2D Receptor–Bearing T Cells as Immunotherapy for Ovarian Cancer
Authors: Barber Amorette , Zhang Tong , DeMars Leslie R. , Conejo-Garcia Jose , Roby Katherine F. , Sentman Charles L.
Published: April 2023

Supplementary Tables 1-2 from Chimeric NKG2D Receptor–Bearing T Cells as Immunotherapy for Ovarian Cancer
Supplementary Figure 2 from A Placenta-Specific Gene Ectopically Activated in Many Human Cancers Is Essentially Involved in Malignant Cell Processes
Authors: Koslowski Michael , Sahin Ugur , Mitnacht-Kraus Rita , Seitz Gerhard , Huber Christoph , Türeci Özlem
Published: April 2023

Supplementary Figure 2 from A Placenta-Specific Gene Ectopically Activated in Many Human Cancers Is Essentially Involved in Malignant Cell Processes
Supplementary Figure Legends 1-2 from Prostate Stem Cell Antigen Vaccination Induces a Long-term Protective Immune Response against Prostate Cancer in the Absence of Autoimmunity
Authors: de la Luz Garcia-Hernandez Maria , Gray Andrew , Hubby Bolyn , Klinger Otto J. , Kast W. Martin
Published: April 2023

Supplementary Figure Legends 1-2 from Prostate Stem Cell Antigen Vaccination Induces a Long-term Protective Immune Response against Prostate Cancer in the Absence of Autoimmunity
Supplementary Figure 2 from Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition In vivo
Authors: Fournier Pierrick G.J. , Daubiné Florence , Lundy Mark W. , Rogers Michael J. , Ebetino Frank H. , Clézardin Philippe
Published: April 2023

Supplementary Figure 2 from Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition In vivo
Supplementary Figure 1 from Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition In vivo
Authors: Fournier Pierrick G.J. , Daubiné Florence , Lundy Mark W. , Rogers Michael J. , Ebetino Frank H. , Clézardin Philippe
Published: April 2023

Supplementary Figure 1 from Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition In vivo
Supplementary Table 1 from Levels of SCS7/FA2H-Mediated Fatty Acid 2-Hydroxylation Determine the Sensitivity of Cells to Antitumor PM02734
Authors: Herrero Ana B. , Astudillo Alma M. , Balboa María A. , Cuevas Carmen , Balsinde Jesús , Moreno Sergio
Published: April 2023

Supplementary Table 1 from Levels of SCS7/FA2H-Mediated Fatty Acid 2-Hydroxylation Determine the Sensitivity of Cells to Antitumor PM02734
Supplementary Figure 1 from Leptin Receptor–Related Immune Response in Colorectal Tumors: The Role of Colonocytes and Interleukin-8
Authors: Abolhassani Mohammad , Aloulou Nijez , Chaumette Marie Thérèse , Aparicio Thomas , Martin-Garcia Nadine , Mansour Hicham , Le Gouvello Sabine , Delchier Jean Charles , Sobhani Iradj
Published: April 2023

Supplementary Figure 1 from Leptin Receptor–Related Immune Response in Colorectal Tumors: The Role of Colonocytes and Interleukin-8
Supplementary Figure 2 from Conditional Loss of Uterine Pten Unfailingly and Rapidly Induces Endometrial Cancer in Mice
Authors: Daikoku Takiko , Hirota Yasushi , Tranguch Susanne , Joshi Ayesha R. , DeMayo Francesco J. , Lydon John P. , Ellenson Lora H. , Dey Sudhansu K.
Published: April 2023

Supplementary Figure 2 from Conditional Loss of Uterine Pten Unfailingly and Rapidly Induces Endometrial Cancer in Mice
Supplementary Figure 2 from Regulation of the Adenomatous Polyposis Coli Gene by the miR-135 Family in Colorectal Cancer
Authors: Nagel Remco , le Sage Carlos , Diosdado Begoña , van der Waal Maike , Oude Vrielink Joachim A.F. , Bolijn Anne , Meijer Gerrit A. , Agami Reuven
Published: April 2023

Supplementary Figure 2 from Regulation of the Adenomatous Polyposis Coli Gene by the miR-135 Family in Colorectal Cancer
Supplementary Tables 1-2, Figure 1 from Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression
Authors: Blázquez Cristina , Salazar María , Carracedo Arkaitz , Lorente Mar , Egia Ainara , González-Feria Luis , Haro Amador , Velasco Guillermo , Guzmán Manuel
Published: April 2023

Supplementary Tables 1-2, Figure 1 from Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression
Supplementary Figures 1-5 from Ionizing Radiation Induces Prostate Cancer Neuroendocrine Differentiation through Interplay of CREB and ATF2: Implications for Disease Progression
Authors: Deng Xuehong , Liu Han , Huang Jiaoti , Cheng Liang , Keller Evan T. , Parsons Sarah J. , Hu Chang-Deng
Published: April 2023

Supplementary Figures 1-5 from Ionizing Radiation Induces Prostate Cancer Neuroendocrine Differentiation through Interplay of CREB and ATF2: Implications for Disease Progression
Supplementary Figure 2 from Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells
Authors: Garbe James C. , Bhattacharya Sanchita , Merchant Batul , Bassett Ekaterina , Swisshelm Karen , Feiler Heidi S. , Wyrobek Andrew J. , Stampfer Martha R.
Published: April 2023

Supplementary Figure 2 from Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells
Supplementary Figure 3 from Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation
Authors: Mohammad Helai P. , Cai Yi , McGarvey Kelly M. , Easwaran Hariharan , Van Neste Leander , Ohm Joyce E. , O'Hagan Heather M. , Baylin Stephen B.
Published: April 2023

Supplementary Figure 3 from Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation
Supplementary Legends 1-4 from From Chronic Feed-Induced Intestinal Inflammation to Adenocarcinoma with Metastases in Salmonid Fish
Authors: Dale Ole B. , Tørud Brit , Kvellestad Agnar , Koppang Hanna S. , Koppang Erling O.
Published: April 2023

Supplementary Legends 1-4 from From Chronic Feed-Induced Intestinal Inflammation to Adenocarcinoma with Metastases in Salmonid Fish
Supplementary Figures 1-2 from Contribution of Granulocyte Colony-Stimulating Factor to the Acute Mobilization of Endothelial Precursor Cells by Vascular Disrupting Agents
Authors: Shaked Yuval , Tang Terence , Woloszynek Jill , Daenen Laura G. , Man Shan , Xu Ping , Cai Shi-Rong , Arbeit Jeffrey M. , Voest Emile E. , Chaplin David J. , Smythe Jon , Harris Adrian , Nathan Paul , Judson Ian , Rustin Gordon , Bertolini Francesco , Link Daniel C. , Kerbel Robert S.
Published: April 2023

Supplementary Figures 1-2 from Contribution of Granulocyte Colony-Stimulating Factor to the Acute Mobilization of Endothelial Precursor Cells by Vascular Disrupting Agents
Supplementary Figures 1-6 from The Development of a Selective Cyclin-Dependent Kinase Inhibitor That Shows Antitumor Activity
Authors: Ali Simak , Heathcote Dean A. , Kroll Sebastian H.B. , Jogalekar Ashutosh S. , Scheiper Bodo , Patel Hetal , Brackow Jan , Siwicka Alekasandra , Fuchter Matthew J. , Periyasamy Manikandan , Tolhurst Robert S. , Kanneganti Seshu K. , Snyder James P. , Liotta Dennis C. , Aboagye Eric O. , Barrett Anthony G.M. , Coombes R. Charles
Published: April 2023

Supplementary Figures 1-6 from The Development of a Selective Cyclin-Dependent Kinase Inhibitor That Shows Antitumor Activity
Supplementary Figure 1 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Authors: Li Angela Y.J. , Boo Lee Ming , Wang Shih-Ya , Lin H. Helen , Wang Clay C.C. , Yen Yun , Chen Benjamin P.C. , Chen David J. , Ann David K.
Published: April 2023

Supplementary Figure 1 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Supplementary Figure 9 from Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors
Authors: Jagani Zainab , Song Keli , Kutok Jeffery L. , Dewar M. Rajan , Melet Armelle , Santos Tanya , Grassian Alexandra , Ghaffari Saghi , Wu Catherine , Ren Ruibao , Rodin Heather Yeckes , Miller Kenneth , Khosravi-Far Roya
Published: April 2023

Supplementary Figure 9 from Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors
Supplementary Figure Legend from Differential Response of Glioma Cells to FOXO1-Directed Therapy
Authors: Lau Cara J. , Koty Zaf , Nalbantoglu Josephine
Published: April 2023

Supplementary Figure Legend from Differential Response of Glioma Cells to FOXO1-Directed Therapy
Supplementary Figure 2 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Authors: Wu Xianglin , Mondal Gourish , Wang Xianshu , Wu Jianmin , Yang Lin , Pankratz Vernon S. , Rowley Matthew , Couch Fergus J.
Published: April 2023

Supplementary Figure 2 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Supplementary Figure Legends 1-4 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Authors: Gilmartin Aidan G. , Bleam Maureen R. , Richter Mark C. , Erskine Symon G. , Kruger Ryan G. , Madden Lenore , Hassler Daniel F. , Smith Gary K. , Gontarek Richard R. , Courtney Mary P. , Sutton David , Diamond Melody A. , Jackson Jeffrey R. , Laquerre Sylvie G.
Published: April 2023

Supplementary Figure Legends 1-4 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Supplementary Figure 1 from Increased Manganese Superoxide Dismutase Expression or Treatment with Manganese Porphyrin Potentiates Dexamethasone-Induced Apoptosis in Lymphoma Cells
Authors: Jaramillo Melba C. , Frye Jennifer B. , Crapo James D. , Briehl Margaret M. , Tome Margaret E.
Published: April 2023

Supplementary Figure 1 from Increased Manganese Superoxide Dismutase Expression or Treatment with Manganese Porphyrin Potentiates Dexamethasone-Induced Apoptosis in Lymphoma Cells
Supplementary Figure Legends 1-2 from ROC1/RBX1 E3 Ubiquitin Ligase Silencing Suppresses Tumor Cell Growth via Sequential Induction of G2-M Arrest, Apoptosis, and Senescence
Authors: Jia Lijun , Soengas Maria S. , Sun Yi
Published: April 2023

Supplementary Figure Legends 1-2 from ROC1/RBX1 E3 Ubiquitin Ligase Silencing Suppresses Tumor Cell Growth via Sequential Induction of G2-M Arrest, Apoptosis, and Senescence
Supplementary Figure and Table Legends 1-2 from NORE1A Tumor Suppressor Candidate Modulates p21CIP1 via p53
Authors: Calvisi Diego F. , Donninger Howard , Vos Michele D. , Birrer Michael J. , Gordon Laura , Leaner Virna , Clark Geoffrey J.
Published: April 2023

Supplementary Figure and Table Legends 1-2 from NORE1A Tumor Suppressor Candidate Modulates p21CIP1 via p53
Supplementary Figure 1 from Identification of Nuclear Export Inhibitors with Potent Anticancer Activity In vivo
Authors: Mutka Sarah C. , Yang Wen Qing , Dong Steven D. , Ward Shannon L. , Craig Darren A. , Timmermans Pieter B.M.W.M. , Murli Sumati
Published: April 2023

Supplementary Figure 1 from Identification of Nuclear Export Inhibitors with Potent Anticancer Activity In vivo
Supplemental Table 5 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Authors: Hennessy Bryan T. , Gonzalez-Angulo Ana-Maria , Stemke-Hale Katherine , Gilcrease Michael Z. , Krishnamurthy Savitri , Lee Ju-Seog , Fridlyand Jane , Sahin Aysegul , Agarwal Roshan , Joy Corwin , Liu Wenbin , Stivers David , Baggerly Keith , Carey Mark , Lluch Ana , Monteagudo Carlos , He Xiaping , Weigman Victor , Fan Cheng , Palazzo Juan , Hortobagyi Gabriel N. , Nolden Laura K. , Wang Nicholas J. , Valero Vicente , Gray Joe W. , Perou Charles M. , Mills Gordon B.
Published: April 2023

Supplemental Table 5
Supplementary Table 1, Figures 1-8 from Smad2 and Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions Transmit Malignant TGF-β Signal in Later Stages of Human Colorectal Cancer
Authors: Matsuzaki Koichi , Kitano Chiaki , Murata Miki , Sekimoto Go , Yoshida Katsunori , Uemura Yoshiko , Seki Toshihito , Taketani Shigeru , Fujisawa Jun-ichi , Okazaki Kazuichi
Published: April 2023

Supplementary Table 1, Figures 1-8 from Smad2 and Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions Transmit Malignant TGF-β Signal in Later Stages of Human Colorectal Cancer
Supplemental Figure 7 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Authors: Hennessy Bryan T. , Gonzalez-Angulo Ana-Maria , Stemke-Hale Katherine , Gilcrease Michael Z. , Krishnamurthy Savitri , Lee Ju-Seog , Fridlyand Jane , Sahin Aysegul , Agarwal Roshan , Joy Corwin , Liu Wenbin , Stivers David , Baggerly Keith , Carey Mark , Lluch Ana , Monteagudo Carlos , He Xiaping , Weigman Victor , Fan Cheng , Palazzo Juan , Hortobagyi Gabriel N. , Nolden Laura K. , Wang Nicholas J. , Valero Vicente , Gray Joe W. , Perou Charles M. , Mills Gordon B.
Published: April 2023

Supplemental Figure 7 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplemental Figure 6A from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Authors: Hennessy Bryan T. , Gonzalez-Angulo Ana-Maria , Stemke-Hale Katherine , Gilcrease Michael Z. , Krishnamurthy Savitri , Lee Ju-Seog , Fridlyand Jane , Sahin Aysegul , Agarwal Roshan , Joy Corwin , Liu Wenbin , Stivers David , Baggerly Keith , Carey Mark , Lluch Ana , Monteagudo Carlos , He Xiaping , Weigman Victor , Fan Cheng , Palazzo Juan , Hortobagyi Gabriel N. , Nolden Laura K. , Wang Nicholas J. , Valero Vicente , Gray Joe W. , Perou Charles M. , Mills Gordon B.
Published: April 2023

Supplemental Figure 6A
Supplemental Figure 5 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Authors: Hennessy Bryan T. , Gonzalez-Angulo Ana-Maria , Stemke-Hale Katherine , Gilcrease Michael Z. , Krishnamurthy Savitri , Lee Ju-Seog , Fridlyand Jane , Sahin Aysegul , Agarwal Roshan , Joy Corwin , Liu Wenbin , Stivers David , Baggerly Keith , Carey Mark , Lluch Ana , Monteagudo Carlos , He Xiaping , Weigman Victor , Fan Cheng , Palazzo Juan , Hortobagyi Gabriel N. , Nolden Laura K. , Wang Nicholas J. , Valero Vicente , Gray Joe W. , Perou Charles M. , Mills Gordon B.
Published: April 2023

Supplemental Figure 5 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Figure 5 from Direct Targeting of the Mucin 1 Oncoprotein Blocks Survival and Tumorigenicity of Human Breast Carcinoma Cells
Authors: Raina Deepak , Ahmad Rehan , Joshi Maya Datt , Yin Li , Wu Zekui , Kawano Takeshi , Vasir Baldev , Avigan David , Kharbanda Surender , Kufe Donald
Published: April 2023

Supplementary Figure 5 from Direct Targeting of the Mucin 1 Oncoprotein Blocks Survival and Tumorigenicity of Human Breast Carcinoma Cells
Supplementary Figure 1 from A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer
Authors: Min Chengyin , Yu Ziyang , Kirsch Kathrin H. , Zhao Yingshe , Vora Siddharth R. , Trackman Philip C. , Spicer Douglas B. , Rosenberg Lynn , Palmer Julie R. , Sonenshein Gail E.
Published: April 2023

Supplementary Figure 1 from A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer
Supplementary Table 5 from High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
Authors: Manié Elodie , Vincent-Salomon Anne , Lehmann-Che Jacqueline , Pierron Gaelle , Turpin Elisabeth , Warcoin Mathilde , Gruel Nadège , Lebigot Ingrid , Sastre-Garau Xavier , Lidereau Rosette , Remenieras Audrey , Feunteun Jean , Delattre Olivier , de Thé Hugues , Stoppa-Lyonnet Dominique , Stern Marc-Henri
Published: April 2023

Supplementary Table 5 from High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
Supplementary Figure 2 from High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
Authors: Manié Elodie , Vincent-Salomon Anne , Lehmann-Che Jacqueline , Pierron Gaelle , Turpin Elisabeth , Warcoin Mathilde , Gruel Nadège , Lebigot Ingrid , Sastre-Garau Xavier , Lidereau Rosette , Remenieras Audrey , Feunteun Jean , Delattre Olivier , de Thé Hugues , Stoppa-Lyonnet Dominique , Stern Marc-Henri
Published: April 2023

Supplementary Figure 2 from High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
Supplementary Table 6 from Identification of Copy Number Abnormalities and Inactivating Mutations in Two Negative Regulators of Nuclear Factor-κB Signaling Pathways in Waldenström's Macroglobulinemia
Authors: Braggio Esteban , Keats Jonathan J. , Leleu Xavier , Van Wier Scott , Jimenez-Zepeda Victor H. , Valdez Riccardo , Schop Roelandt F.J. , Price-Troska Tammy , Henderson Kimberly , Sacco Antonio , Azab Feda , Greipp Philip , Gertz Morie , Hayman Suzanne , Rajkumar S. Vincent , Carpten John , Chesi Marta , Barrett Michael , Stewart A. Keith , Dogan Ahmet , Bergsagel P. Leif , Ghobrial Irene M. , Fonseca Rafael
Published: April 2023

Supplementary Table 6 from Identification of Copy Number Abnormalities and Inactivating Mutations in Two Negative Regulators of Nuclear Factor-κB Signaling Pathways in Waldenström's Macroglobulinemia
Supplementary Table 4 from Identification of Copy Number Abnormalities and Inactivating Mutations in Two Negative Regulators of Nuclear Factor-κB Signaling Pathways in Waldenström's Macroglobulinemia
Authors: Braggio Esteban , Keats Jonathan J. , Leleu Xavier , Van Wier Scott , Jimenez-Zepeda Victor H. , Valdez Riccardo , Schop Roelandt F.J. , Price-Troska Tammy , Henderson Kimberly , Sacco Antonio , Azab Feda , Greipp Philip , Gertz Morie , Hayman Suzanne , Rajkumar S. Vincent , Carpten John , Chesi Marta , Barrett Michael , Stewart A. Keith , Dogan Ahmet , Bergsagel P. Leif , Ghobrial Irene M. , Fonseca Rafael
Published: April 2023

Supplementary Table 4 from Identification of Copy Number Abnormalities and Inactivating Mutations in Two Negative Regulators of Nuclear Factor-κB Signaling Pathways in Waldenström's Macroglobulinemia
Supplementary Figures 1-3, Tables 1-4 from The Receptor Interacting Protein 1 Inhibits p53 Induction through NF-κB Activation and Confers a Worse Prognosis in Glioblastoma
Authors: Park Seongmi , Hatanpaa Kimmo J. , Xie Yang , Mickey Bruce E. , Madden Christopher J. , Raisanen Jack M. , Ramnarain Deepti B. , Xiao Guanghua , Saha Debabrata , Boothman David A. , Zhao Dawen , Bachoo Robert M. , Pieper Russell O. , Habib Amyn A.
Published: April 2023

Supplementary Figures 1-3, Tables 1-4 from The Receptor Interacting Protein 1 Inhibits p53 Induction through NF-κB Activation and Confers a Worse Prognosis in Glioblastoma
Supplementary Table 2 from CD38/CD31, the CCL3 and CCL4 Chemokines, and CD49d/Vascular Cell Adhesion Molecule-1 Are Interchained by Sequential Events Sustaining Chronic Lymphocytic Leukemia Cell Survival
Authors: Zucchetto Antonella , Benedetti Dania , Tripodo Claudio , Bomben Riccardo , Dal Bo Michele , Marconi Daniela , Bossi Fleur , Lorenzon Debora , Degan Massimo , Rossi Francesca Maria , Rossi Davide , Bulian Pietro , Franco Vito , Del Poeta Giovanni , Deaglio Silvia , Gaidano Gianluca , Tedesco Francesco , Malavasi Fabio , Gattei Valter
Published: April 2023

Supplementary Table 2 from CD38/CD31, the CCL3 and CCL4 Chemokines, and CD49d/Vascular Cell Adhesion Molecule-1 Are Interchained by Sequential Events Sustaining Chronic Lymphocytic Leukemia Cell Survival
Supplementary Figure 1 from Glucocorticoid-Induced Tumor Necrosis Factor Receptor–Related Protein Ligand Subverts Immunosurveillance of Acute Myeloid Leukemia in Humans
Authors: Baessler Tina , Krusch Matthias , Schmiedel Benjamin Joachim , Kloss Mercedes , Baltz Katrin Miriam , Wacker Alexander , Schmetzer Helga Maria , Salih Helmut Rainer
Published: April 2023

Supplementary Figure 1 from Glucocorticoid-Induced Tumor Necrosis Factor Receptor–Related Protein Ligand Subverts Immunosurveillance of Acute Myeloid Leukemia in Humans
Supplementary Figures 1-3 from Suppression of Human Solid Tumor Growth in Mice by Intratumor and Systemic Inoculation of Histidine-Rich and pH-Dependent Host Defense–like Lytic Peptides
Authors: Makovitzki Arik , Fink Avner , Shai Yechiel
Published: April 2023

Supplementary Figures 1-3 from Suppression of Human Solid Tumor Growth in Mice by Intratumor and Systemic Inoculation of Histidine-Rich and pH-Dependent Host Defense–like Lytic Peptides
Supplementary Table 2b from Evidence for Cancer Stem Cells in Human Endometrial Carcinoma
Authors: Hubbard Sonya A. , Friel Anne M. , Kumar Beena , Zhang Ling , Rueda Bo R. , Gargett Caroline E.
Published: April 2023

Supplementary Table 2b from Evidence for Cancer Stem Cells in Human Endometrial Carcinoma
Supplementary Table 7 from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Authors: Dey Julien H. , Bianchi Fabrizio , Voshol Johannes , Bonenfant Debora , Oakeley Edward J. , Hynes Nancy E.
Published: April 2023

Supplementary Table 7 from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Supplementary Table 2 from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Authors: Dey Julien H. , Bianchi Fabrizio , Voshol Johannes , Bonenfant Debora , Oakeley Edward J. , Hynes Nancy E.
Published: April 2023

Supplementary Table 2 from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Supplementary Figure 5 from Design of Agonistic Altered Peptides for the Robust Induction of CTL Directed towards H-2Db in Complex with the Melanoma-Associated Epitope gp100
Authors: van Stipdonk Marianne J.B. , Badia-Martinez Daniel , Sluijter Marjolein , Offringa Rienk , van Hall Thorbald , Achour Adnane
Published: April 2023

Supplementary Figure 5 from Design of Agonistic Altered Peptides for the Robust Induction of CTL Directed towards H-2Db in Complex with the Melanoma-Associated Epitope gp100
Supplementary Methods, Figure Legends 1-8 from Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation
Authors: Hide Takuichiro , Takezaki Tatsuya , Nakatani Yuka , Nakamura Hideo , Kuratsu Jun-ichi , Kondo Toru
Published: April 2023

Supplementary Methods, Figure Legends 1-8 from Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation
Supplementary Figure 6 from Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation
Authors: Hide Takuichiro , Takezaki Tatsuya , Nakatani Yuka , Nakamura Hideo , Kuratsu Jun-ichi , Kondo Toru
Published: April 2023

Supplementary Figure 6 from Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation
Supplementary Table 1 from A Proteomic Approach for the Identification of Vascular Markers of Liver Metastasis
Authors: Borgia Beatrice , Roesli Christoph , Fugmann Tim , Schliemann Christoph , Cesca Marta , Neri Dario , Giavazzi Raffaella
Published: April 2023

Supplementary Table 1 from A Proteomic Approach for the Identification of Vascular Markers of Liver Metastasis
Supplementary Figures 1-9 from Increased Expression of α6 Integrin in Endothelial Cells Unveils a Proangiogenic Role for Basement Membrane
Authors: Primo Luca , Seano Giorgio , Roca Cristina , Maione Federica , Gagliardi Paolo Armando , Sessa Roberto , Martinelli Marianna , Giraudo Enrico , di Blasio Laura , Bussolino Federico
Published: April 2023

Supplementary Figures 1-9 from Increased Expression of α6 Integrin in Endothelial Cells Unveils a Proangiogenic Role for Basement Membrane
Supplementary Figure 1 from Immature Immunosuppressive CD14+HLA-DR−/low Cells in Melanoma Patients Are Stat3hi and Overexpress CD80, CD83, and DC-Sign
Authors: Poschke Isabel , Mougiakakos Dimitrios , Hansson Johan , Masucci Giuseppe V. , Kiessling Rolf
Published: April 2023

Supplementary Figure 1 from Immature Immunosuppressive CD14+HLA-DR−/low Cells in Melanoma Patients Are Stat3hi and Overexpress CD80, CD83, and DC-Sign
Supplementary Table 1 from Gene Expression: Protein Interaction Systems Network Modeling Identifies Transformation-Associated Molecules and Pathways in Ovarian Cancer
Authors: Bapat Sharmila A. , Krishnan Anagha , Ghanate Avinash D. , Kusumbe Anjali P. , Kalra Rajkumar S.
Published: April 2023

Supplementary Table 1 from Gene Expression: Protein Interaction Systems Network Modeling Identifies Transformation-Associated Molecules and Pathways in Ovarian Cancer
Dataset 2 from Gene Expression: Protein Interaction Systems Network Modeling Identifies Transformation-Associated Molecules and Pathways in Ovarian Cancer
Authors: Bapat Sharmila A. , Krishnan Anagha , Ghanate Avinash D. , Kusumbe Anjali P. , Kalra Rajkumar S.
Published: April 2023

Dataset 2 from Gene Expression: Protein Interaction Systems Network Modeling Identifies Transformation-Associated Molecules and Pathways in Ovarian Cancer
Supplementary Figure 5 from NPM-ALK Oncogenic Tyrosine Kinase Controls T-Cell Identity by Transcriptional Regulation and Epigenetic Silencing in Lymphoma Cells
Authors: Ambrogio Chiara , Martinengo Cinzia , Voena Claudia , Tondat Fabrizio , Riera Ludovica , di Celle Paola Francia , Inghirami Giorgio , Chiarle Roberto
Published: April 2023

Supplementary Figure 5 from NPM-ALK Oncogenic Tyrosine Kinase Controls T-Cell Identity by Transcriptional Regulation and Epigenetic Silencing in Lymphoma Cells
Supplementary Figure 4 from NPM-ALK Oncogenic Tyrosine Kinase Controls T-Cell Identity by Transcriptional Regulation and Epigenetic Silencing in Lymphoma Cells
Authors: Ambrogio Chiara , Martinengo Cinzia , Voena Claudia , Tondat Fabrizio , Riera Ludovica , di Celle Paola Francia , Inghirami Giorgio , Chiarle Roberto
Published: April 2023

Supplementary Figure 4 from NPM-ALK Oncogenic Tyrosine Kinase Controls T-Cell Identity by Transcriptional Regulation and Epigenetic Silencing in Lymphoma Cells
Supplementary Table 2 from Genome-Wide Mapping of Estrogen Receptor-β–Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1
Authors: Zhao Chunyan , Gao Hui , Liu Yawen , Papoutsi Zoi , Jaffrey Sadaf , Gustafsson Jan-Åke , Dahlman-Wright Karin
Published: April 2023

Supplementary Table 2 from Genome-Wide Mapping of Estrogen Receptor-β–Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1
Supplementary Figure 4 from Genome-Wide Mapping of Estrogen Receptor-β–Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1
Authors: Zhao Chunyan , Gao Hui , Liu Yawen , Papoutsi Zoi , Jaffrey Sadaf , Gustafsson Jan-Åke , Dahlman-Wright Karin
Published: April 2023

Supplementary Figure 4 from Genome-Wide Mapping of Estrogen Receptor-β–Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1
Supplementary Table 4 from Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling
Authors: Sullivan James P. , Spinola Monica , Dodge Michael , Raso Maria G. , Behrens Carmen , Gao Boning , Schuster Katja , Shao Chunli , Larsen Jill E. , Sullivan Laura A. , Honorio Sofia , Xie Yang , Scaglioni Pier P. , DiMaio J. Michael , Gazdar Adi F. , Shay Jerry W. , Wistuba Ignacio I. , Minna John D.
Published: April 2023

Supplementary Table 4 from Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling
Supplementary Table 1 from Active Immunotherapy Induces Antibody Responses That Target Tumor Angiogenesis
Authors: Schoenfeld Jonathan , Jinushi Masahisa , Nakazaki Yukoh , Wiener Daniel , Park Joosang , Soiffer Robert , Neuberg Donna , Mihm Martin , Hodi F. Stephen , Dranoff Glenn
Published: April 2023

Supplementary Table 1 from Active Immunotherapy Induces Antibody Responses That Target Tumor Angiogenesis
Supplementary Figure 1 from HEF1 Is a Crucial Mediator of the Proliferative Effects of Prostaglandin E2 on Colon Cancer Cells
Authors: Xia Dianren , Holla Vijaykumar R. , Wang Dingzhi , Menter David G. , DuBois Raymond N.
Published: April 2023

Supplementary Figure 1 from HEF1 Is a Crucial Mediator of the Proliferative Effects of Prostaglandin E2 on Colon Cancer Cells
Supplementary Tables 1-4 from In silico Modeling and In vivo Efficacy of Cancer-Preventive Vaccinations
Authors: Palladini Arianna , Nicoletti Giordano , Pappalardo Francesco , Murgo Annalisa , Grosso Valentina , Stivani Valeria , Ianzano Marianna L. , Antognoli Agnese , Croci Stefania , Landuzzi Lorena , De Giovanni Carla , Nanni Patrizia , Motta Santo , Lollini Pier-Luigi
Published: April 2023

Supplementary Tables 1-4 from In silico Modeling and In vivo Efficacy of Cancer-Preventive Vaccinations
Supplementary Figures 1-6 from The Phosphoinositide 3-Kinase Regulatory Subunit p85α Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling
Authors: Taniguchi Cullen M. , Winnay Jonathon , Kondo Tatsuya , Bronson Roderick T. , Guimaraes Alexander R. , Alemán José O. , Luo Ji , Stephanopoulos Gregory , Weissleder Ralph , Cantley Lewis C. , Kahn C. Ronald
Published: April 2023

Supplementary Figures 1-6 from The Phosphoinositide 3-Kinase Regulatory Subunit p85α Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling
Supplementary Figure Legend from Loss of Function of the Tumor Suppressor DKC1 Perturbs p27 Translation Control and Contributes to Pituitary Tumorigenesis
Authors: Bellodi Cristian , Krasnykh Olya , Haynes Nikesha , Theodoropoulou Marily , Peng Guang , Montanaro Lorenzo , Ruggero Davide
Published: April 2023

Supplementary Figure Legend from Loss of Function of the Tumor Suppressor DKC1 Perturbs p27 Translation Control and Contributes to Pituitary Tumorigenesis
Supplementary Figure 8 from AXL Is an Essential Factor and Therapeutic Target for Metastatic Ovarian Cancer
Authors: Rankin Erinn B. , Fuh Katherine C. , Taylor Tiffany E. , Krieg Adam J. , Musser Margaret , Yuan Jenny , Wei Kevin , Kuo Calvin J. , Longacre Teri A. , Giaccia Amato J.
Published: April 2023

Supplementary Figure 8 from AXL Is an Essential Factor and Therapeutic Target for Metastatic Ovarian Cancer
Supplementary Figure 6 from Prostate Cancer Radiosensitization through Poly(ADP-Ribose) Polymerase-1 Hyperactivation
Authors: Dong Ying , Bey Erik A. , Li Long-Shan , Kabbani Wareef , Yan Jingsheng , Xie Xian-Jin , Hsieh Jer-Tsong , Gao Jinming , Boothman David A.
Published: April 2023

Supplementary Figure 6 from Prostate Cancer Radiosensitization through Poly(ADP-Ribose) Polymerase-1 Hyperactivation
Supplementary Data 2 from Zoledronic Acid Potentiates mTOR Inhibition and Abolishes the Resistance of Osteosarcoma Cells to RAD001 (Everolimus): Pivotal Role of the Prenylation Process
Authors: Moriceau Gatien , Ory Benjamin , Mitrofan Laura , Riganti Chiara , Blanchard Frédéric , Brion Régis , Charrier Céline , Battaglia Séverine , Pilet Paul , Denis Marc G. , Shultz Leonard D. , Mönkkönen Jukka , Rédini Françoise , Heymann Dominique
Published: April 2023

Supplementary Data 2 from Zoledronic Acid Potentiates mTOR Inhibition and Abolishes the Resistance of Osteosarcoma Cells to RAD001 (Everolimus): Pivotal Role of the Prenylation Process
Supplementary Tables 1-4, Figures 1-2 from Identification of Susceptibility Loci in a Mouse Model of KRASG12D-Driven Pancreatic Cancer
Authors: Jorgenson Tonia C. , Williams Bret R. , Wendland Allyson , Bilger Andrea , Sandgren Eric P. , Drinkwater Norman R.
Published: April 2023

Supplementary Tables 1-4, Figures 1-2 from Identification of Susceptibility Loci in a Mouse Model of KRASG12D-Driven Pancreatic Cancer
Supplementary Figure 1 from Variable Inhibition of Thrombospondin 1 against Liver and Lung Metastases through Differential Activation of Metalloproteinase ADAMTS1
Authors: Lee Yoon-Jin , Koch Moritz , Karl Daniel , Torres-Collado Antoni X. , Fernando Namali T. , Rothrock Courtney , Kuruppu Darshini , Ryeom Sandra , Iruela-Arispe M. Luisa , Yoon Sam S.
Published: April 2023

Supplementary Figure 1 from Variable Inhibition of Thrombospondin 1 against Liver and Lung Metastases through Differential Activation of Metalloproteinase ADAMTS1
Supplementary Tables 1-7 from Decreased Mitochondrial Mutagenesis during Transformation of Human Breast Stem Cells into Tumorigenic Cells
Authors: Ahn Eun Hyun , Lee Seung Hyuk , Kim Joon Yup , Chang Chia-Cheng , Loeb Lawrence A.
Published: April 2023

Seven supplementary tables. Table S1. Data yield and Duplex Sequencing statistics. Table S2. Mutation contexts significantly differ between normal stem cells and transformed cells. Table S3. Homoplasmic variants in the whole mtDNA identified using Duplex Sequencing. Table S4. Rare variants in the whole mtDNA of HBEC identified using Duplex Sequencing. Table S5. Mutations that are clonally expanded or negatively selected toward tumorigenesis. Table S6. Distribution of nonsynonymous mutations of rare variants in the whole mtDNA and within mtDNA coding regions. Table S7. The number of non-synonymous mutations of rare variants in mitochondrial protein-coding regions.
Supplementary Figure 2 from Decreased Mitochondrial Mutagenesis during Transformation of Human Breast Stem Cells into Tumorigenic Cells
Authors: Ahn Eun Hyun , Lee Seung Hyuk , Kim Joon Yup , Chang Chia-Cheng , Loeb Lawrence A.
Published: April 2023

Mutation signature correlation graph
Fig, S2 from RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis
Authors: Zeng Fanxin , Chen Xiao , Cui Weiyi , Wen Wei , Lu Fujian , Sun Xueting , Ma Dongwei , Yuan Ye , Li Zezhong , Hou Ning , Zhao Hong , Bi Xinyu , Zhao Jianjun , Zhou Jianguo , Zhang Yan , Xiao Rui-Ping , Cai Jianqiang , Zhang Xiuqin
Published: April 2023

Figure S2. Nuclear localization of NF-kB is Increased in CRC (A) Representative photomicrographs of immunostaining for NF-ÎºB and phosphorylated NF-ÎºB (P65 and p-P65) in normal and CRC tissues. Scale bar = 50Î¼m.
Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
Authors: Jenkins Samir V. , Robeson Michael S. , Griffin Robert J. , Quick Charles M. , Siegel Eric R. , Cannon Martin J. , Vang Kieng B. , Dings Ruud P.M.
Published: April 2023

Supplemental data regarding cecum morphology, body weights, adhesion molecule expression in spleen and thymus, spleen size, tumor and stroma cell viability, and IFN-g and VEGF serum levels after induction of dysbiosis.
Supplementary Figure 3 from Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma
Authors: Fultang Livingstone , Gamble Laura D. , Gneo Luciana , Berry Andrea M. , Egan Sharon A. , De Bie Fenna , Yogev Orli , Eden Georgina L. , Booth Sarah , Brownhill Samantha , Vardon Ashley , McConville Carmel M. , Cheng Paul N. , Norris Murray D. , Etchevers Heather C. , Murray Jayne , Ziegler David S. , Chesler Louis , Schmidt Ronny , Burchill Susan A. , Haber Michelle , De Santo Carmela , Mussai Francis
Published: April 2023

Supplementary Figure 3 Neuroblastoma conditioning upregulates IL-1ï�¢ï€ and TNF-ï�¡ï€ expression in macrophages
Supplemental Figures from Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells
Authors: Erber Johanna , Steiner Joachim D. , Isensee Jörg , Lobbes Leonard A. , Toschka André , Beleggia Filippo , Schmitt Anna , Kaiser Rainer W. J. , Siedek Florian , Persigehl Thorsten , Hucho Tim , Reinhardt Hans C.
Published: April 2023

Figure S1 shows single agent dose-response curves of 18 compounds employed in the screen. Figure S2 shows synergy scores of 23 compound combinations. Figure S3 shows the apoptotic effects of single agent inhibitors and their combinations on a panel of 24 cell lines. Figure S4 shows synergy scores for 6x6 concentration combinations of combined CHK1/GLUT1 or ATR/GLUT1 inhibition as well as tumor volume fold changes of A549- and HCC44-derived xenografts treated with the CHK1-inhibitor, GLUT1-inhibitor or the combination of both. Figure S5 shows synergy scores for 6x6 concentration combinations of combined CHK1/HER2 inhibition as well as tumor volume fold changes of A549- and HCC44-derived xenografts treated with the CHK1-inhibitor, HER2-inhibitor or the combination of both. Figure S6 shows that sensitive cell lines are enriched for MTORC1 signalling and sensitivity of murine KrasG12D/wt;Trp53-/--driven NSCLC and soft tissue sarcoma sarcoma. Figure S7 shows sanger sequencing results confirming driver lesions of the core cell line panel. Figure S8 shows that siRNA-mediated knockdown is efficient and validates target specifity. Figure S9 shows that drug synergy is preserved for chemically distinct inhibitors of CHK1 and ATR and on-target activity of PF477736 and VE822. Figure S10 shows that combined inhibitions of the ATR/CHK1 axis and GLUT1 synergistically induces S-phase-specific genotoxic stress and apoptosis in A549 cells and single toxicity of CHK1/ATR inhibition in A498 cells Figure S11 shows that combined inhibition of ATR/CHK1 and GLUT1 synergistically induces phosphorylation of H2AX in sensitive cells. Figure S12 shows original plots of High-content screening microscopy. Figure S13 shows that treatment regimens have no significant effects on body weights of KrasLSL.G12D/wt;Trp53fl/fl mice.
Table S4 from Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish
Authors: Henderson Fiona , Johnston Hannah R. , Badrock Andrew P. , Jones Emrys A. , Forster Duncan , Nagaraju Raghavendar T. , Evangelou Christos , Kamarashev Jivko , Green Michael , Fairclough Michael , Ramirez Irene Barinaga-Rementeria , He Shuning , Snaar-Jagalska B. Ewa , Hollywood Katherine , Dunn Warwick B. , Spaink Herman P. , Smith Michael P. , Lorigan Paul , Claude Emmanuelle , Williams Kaye J. , McMahon Adam W. , Hurlstone Adam
Published: April 2023

Characteristics of established melanoma cell lines utilised in this study.
Supplementary Figure S1 from Transcriptomics Associates Molecular Features with 18F-Fluorocholine PET/CT Imaging Phenotype and Its Potential Relationship to Survival in Hepatocellular Carcinoma
Authors: Kwee Sandi A. , Tiirikainen Maarit , Sato Miles M. , Acoba Jared D. , Wei Runmin , Jia Wei , Le Marchand Loic , Wong Linda L.
Published: April 2023

SUV Ratios (was previously Figure S4, but renumbered to match call out order)
Figure S6 from Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Authors: So Jae Young , Skrypek Nicolas , Yang Howard H. , Merchant Anand S. , Nelson George W. , Chen Wei-Dong , Ishii Hiroki , Chen Jennifer M. , Hu Gangqing , Achyut Bhagelu R. , Yoon Esther C. , Han Liying , Huang Chuanshu , Cam Margaret C. , Zhao Keji , Lee Maxwell P. , Yang Li
Published: April 2023

DNMT1 and DNMT3A expression in human data sets
Supplementary Table S1 from Prostaglandin E1 Inhibits GLI2 Amplification–Associated Activation of the Hedgehog Pathway and Drug Refractory Tumor Growth
Authors: Wu Fujia , Zhang Chenze , Zhao Chen , Wu Hao , Teng Zhaoqian , Jiang Tao , Wang Yu
Published: April 2023

Gene-specific primers used in this paper.
Supplementary Data from p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis
Authors: Wang Fang , Qi Xiao-Mei , Wertz Ryan , Mortensen Matthew , Hagen Catherine , Evans John , Sheinin Yuri , James Michael , Liu Pengyuan , Tsai Susan , Thomas James , Mackinnon Alexander , Dwinell Michael , Myers Charles R. , Bartrons Bach Ramon , Fu Liwu , Chen Guan
Published: April 2023

Suppl Materials and Methods 7 Suppl figures
Figure S4 from p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis
Authors: Wang Fang , Qi Xiao-Mei , Wertz Ryan , Mortensen Matthew , Hagen Catherine , Evans John , Sheinin Yuri , James Michael , Liu Pengyuan , Tsai Susan , Thomas James , Mackinnon Alexander , Dwinell Michael , Myers Charles R. , Bartrons Bach Ramon , Fu Liwu , Chen Guan
Published: April 2023

Figure S4. PFKFB3 and GLUT2 silencing only inhibits ECAR in KPC, but not in KPC/p38ÃƒÅ½Ã,Â³ KO cells, whereas PFKFB3/S467D expression increases glycolysis and/or growth independent of p38ÃƒÅ½Ã,Â³ and the PFKFB3/S467A mutant only suppresses PFK activity and ECAR in KPC cells.