bluuebunny/crossref_metadata_2025 huggingface dataset:
Valiant, vital and virtuous - A time-snap review
Authors: Itkonen Matti
Published: October 2021

A time-snap review – moments captured pictorially – means the creation of multi-layered observation. The enquiring gaze then extends beyond the present moment: to its existential roots. However, it is not a question of presenting an historical list, a collection of topics of various types and periods. Of course, understanding the present also requires knowledge of the people and events of the past. In this way it also becomes possible to study the recurring nature of existence. Can war-related travel also count as cultural travel? Is it possible to talk about war tourism? Presumably, in many countries the answer to this will be positive. It relates to the history of ideas and also to national sentiment. This kind of cultural education may be indoctrinating in character, with the goal of insinuating into people's minds the concept of the incomparable excellence of their own nationality. The spirit of the 2010s contains shades of indoctrination. Fortunately, alongside this struggle to impress, education for democracy is also present. Photographs and poetry are powerful media, helping us to create a nostalgia for being. Then, too, a longing for the past is awakened. It is here that a philosophy of yearning or wistfulness is needed, providing an exploratory tool for analyzing the nature of the individual and the community. Modernity needs philosophical poet-travellers. They are adept at loving the wisdom of travel.
Design and Development of GSR Biofeedback Device
Authors: Hashemi Maryam
Published: October 2021

It has been a long time that human is interested in learning how to control involuntary actions such as heartbeat, blood pressure, breathing, etc., so a lot of research has been done on this issue so far. One of the methods using in this field is biofeedback, in which someone can roughly control an involuntary action or having better control over some voluntary actions such as muscle contraction through some visual or audio feedback from those actions. This study is to design and development of one biofeedback instrument, which is GSR (Galvanic Skin Response), and examine some signals that have been taken by this device.
Pendampingan dan Pembuatan Konten Video untuk Mendukung Pemasaran melalui Media Sosial Bagi UMKM Fashion
Authors: Wibisono Yohanes Priadi , Primasari Clara Hetty , Setiawan Danniel
Published: October 2021

Trend Fashion belakangan ini menjadi industry yang paling menguntungkan dan menjadi popular di Indonesia. Berdasarkan data dari CNBC Indonesia (2019), perkembangan industry fashion mampu berkontribusi sekitar 18,01% atau Rp. 116 Triliun. Meningkatnya jumlah pemain dalam industri fashion mengakibatkan semakin tinggi pula tingkat pesaingan pada industri tersebut. Persaingan dalam pemasaran produk fashion melalui media social dan marketplace menjadi salah satu tantangan tersendiri bagi para pelaku industri fashion. Hal ini berdampak pada UMKM khususnya di bidang fashion. Mereka  membutuhkan metode pemasaran baru yang sebelumnya berupa foto, menjadi konten video. Dalam pemasaran yang dilakukan, tidak semua UMKM khususnya di bidang fashion menguasai metode pemasaran menggunakan konten video. Berdasarkan Situasi dan kondisi, maka disusunlah konsep Pengabdian Masyarakat ini untuk memberi pelatihan dan pembuatan konten video marketing.
SOSIALISASI PENCEGAHAN PENYEBARAN COVID-19 DAN PENGEMBANGAN KETAHANAN PANGAN DI KELURAHAN SABARU PALANGKA RAYA
Authors: Firlianty Firlianty
Published: October 2021

Pencegahan penularan covid-19 sangat penting saat ini untuk diterapkan dalam masyarakat, karena bahaya yang diakibat virus ini sangat mengancam jiwa dan penularan yang sangat cepat. Peningkatan kesadaran masyarakat untuk pencegahan penularan covid-19 ini menjadi salah satu kegiatan pengabdian masyarakat yang dilaksanakan di kelurahan sabaru.  Ketahanan pangan merupakan terjemahan dari food security mencakup banyak aspek dan luas sehingga setiap orang mencoba menterjemahkan sesuai dengan tujuan dan ketersediaan data. Fungsi ketahanan pangan sebagai prasyarat untuk terjaminnya akses pangan determinan utama dari inovasi ilmu pengetahuan, teknologi dan tenaga kerja produktif serta fungsi ketahanan pangan sebagai salah satu cerminan lingkungan perekonomian yang stabil dan kondusif bagi pembangunan. Setiap negara senantiasa berusaha membangun sistem ketahanan pangan yang mantap. Oleh sebab itu sangat rasional dan wajar kalau Indonesia menjadikan program pemantapan ketahanan pangan nasional sebagai prioritas utama pembangunannya.  Pandemi Covid 19 yang melanda seluruh negeri menyebabkan masyarakat sangat membutuhkan bahan pangan, karena hal tersebut maka pemerintah dengan gencar nya memberikan arahan sosialisasi mengenai ketahanan pangan dengan memanfaatkan lahan pekarangan untuk menanam sayuran sebagai upaya dalam rangka pemenuhan gizi masyarakat yang tujuannya untuk meningkatkan imunitas tubuh agar tidak mudah terserang virus covid 19.
STRATEGI REORIENTASI KURIKULUM PENDIDIKAN MATEMATIKA DI ERA REVOLUSI INDUSTRI 4.0
Authors: M.Pd Dona Fitriawan,
Published: October 2021

Kegiatan PKM adalah dari kondisi dan potensi industri di Provinsi Kalimantan Barat (BPS, 2018). Industri tersebut antara lain adalah smelter, agrobisnis, pengolahan karet, pengolahan ikan dan tangkapan air lain, pengolahan kelapa sawit, pengolahan kayu, pariwisata, dan manufaktur. Dari segi fisik, penempatan industri-indistri tersebut telah sesuai dengan tata ruang dan wilayah, yakni pengelolaan kepada layak dan kelestarian lingkungan sosial dan alam.  Dengan adanya industri sebagaimana dimaksud, rerata pertumbuhan ekonomi di Kalimantan Barat adalah 4,95%. Angka pertumbuhan ekonomi tersebut adalah relevan dengan kebutuhan matematika industri, terutama matematika sekolah samapai tingkat SMA/sederajat. Relevansi PKM ini terhadap kondisi dan potensi pembanguanan industri di Kalimantan Barat adalah bahwa: (1) pertumbuhan industri meningkat rerata sebesar 0,5% per tahun, dilihat dari pertumbuhan jenis dan skala industri dan (2) peningkatan jumlah tenaga kerja di bidang industri meningkat rerata 2% per tahun dari seluruh angkatan kerja dari lulusan satuan pendidikan SMP, SMA, dan sederajat serta lulusan perguruan tinggi. Terdapat tiga (3) prioritas utama yakni: (1) pertumbuhan berarti, dengan mengembangkan ekonomi berbasis pengetahuan dan inovasi; (2) pertumbuhan berkelanjutan, dengan mempromosikan sumber-sumber yang efisien, lebih hijau (ramah lingkungan), dan ekonomi kompetitif; dan (3) pertumbuhan inklusif, dengan membina kegiatan dan perkerjaan perekomian skala tinggi yang memberikan sumbangan besar pada pertumbuhan ekonomi, sosial dan keterpaduan wilayah.
PENERAPAN TEKNOLOGI LAMPU CELUP BAWAH AIR (LACUBA) UNTUK NELAYAN BAGAN TANCAP GUNA MENINGKATKAN KAPASITAS IKAN TANGKAPAN
Authors: Imansyah Fitri
Published: October 2021

ABSTRAK: Bagan merupakan salah satu jenis alat tangkap yang menggunakan lampu sebagai alat bantu pengumpul ikan. Cahaya lampu diharapkan dapat merangsang ikan untuk datang dan berkumpul disekitar sumber cahaya sampai pada suatu catchable area tertentu, lalu penangkapan dilakukan dengan alat jaring maupun pancing. Penggunaan lampu untuk penangkapan ikan saat ini berkembang pesat, hampir semua alat tangkap menggunakan lampu sebagai alat bantu pengumpul  ikan.  Aplikasi  teknologi  ini  bertujuan  untuk  meningkatkan  hasil  tangkapan  ikan nelayan bagan tancap di Kecamatan Sungai Kunyit melalui penerapan teknologi lampu celup bawah air (lacuba) berbasis lampu LED. Lampu celup bawah air diterapkan pada bagan tancap dengan intensitas dan  warna  tertentu  untuk  mencari  intensitas  cahaya  dan  warna  yang  memberikan  hasil tangkapan yang terbaik. Pemakaian lampu celup bawah air pada alat penangkapan ikan, dapat diketahui bahwa sumber kekuatan sumber cahaya dan intensitas cahaya mempunyai pengaruh besar dalam usaha memikat ikan. Demikian juga dengan letak lampu di atas permukaan air (surface lamp) dan di dalam air (underwater lamp) serta jarak sumber cahaya dengan permukaan air. Pada intensitas cahaya yang sama tetapi pada jarak yang berbeda akan memberikan hasil tangkapan yang berbeda akan memberikan hasil tangkapan yang berbeda pula hasil tangkapan yang diberikan. Dalam memanfaatkan teknologi tepat guna berupa lampu celup bawah air diharapkan dapat mewujudkan modernisasi usaha perikanan yang diikuti alokasi sarana dan prasarana yang diperlukan agar nelayan mampu mengembangkan usahanya sebagai usaha yang tangguh dan memiliki daya saing yang kuat, serta meningkatkan produktivitas dan modernisasi usaha sehingga dicapai perbaikan sistem pengembangan usaha perikanan serta pengolahan dan pemanfaatan sumber daya alam yang ada di lokasi usaha perikanan agar ketersediaan ikan selalu terpenuhi.
Teaching Reform of Obstetrics and Gynecology Nursing Course in Higher Vocational Colleges Based on OBE Education Concept from the Perspective of Big Data
Authors:   School of nursing and health, Guangdong Lingnan Institute of Technology,Guangzhou, Guangdong Province, 510663,China, Huang Shanshan , Chen Huifang ,   School of pharmacy, Guangdong Lingnan Institute of Technology, Guangzhou, Guangdong Province, 510663, China, Cao Hua ,   School of nursing and health, Guangdong Lingnan Institute of Technology,Guangzhou, Guangdong Province, 510663,China, Yan Lulu ,   School of nursing and health, Guangdong Lingnan Institute of Technology,Guangzhou, Guangdong Province, 510663,China
Published: October 2021

The application of big data puts forward new requirements for the talent training mode and curriculum reform of big data in higher vocational colleges. Through statistical data, the classroom quality can be measured, evaluated and traced. Under the framework of “Internet plus big data”, taking the cultivation of innovative ability as the core, realizing the multidimensional integration of technology and science, general knowledge and specialty, teaching and research, and teachers and students has become a new concept and Practice for improving the quality of big data talents training in higher vocational colleges. Obstetrics and gynecology nursing is one of the core courses of nursing specialty in higher vocational colleges, which is of great significance to the cultivation of professional talents. The purpose of nursing specialty in higher vocational colleges is to cultivate skilled and technical applied talents to meet the needs of medical and health posts, which requires the combination of theoretical knowledge and practical skills, so as to cultivate students’ clinical thinking and ability. There are some problems in the course design of Obstetrics and gynecology nursing in higher vocational colleges, such as the derailment of theoretical teaching and practical teaching, teaching materials lagging behind the update of clinical skills, students’ low learning initiative, single teaching mode and so on. Based on the OBE teaching concept from the perspective of big data, this paper carries out curriculum design, curriculum implementation and Curriculum Evaluation Guided by students’ learning achievements, and through the reverse design of achievements, highlights the student-centered, quantifies teaching output, and cultivates students’ learning ability and creativity. By reasonably mobilizing students’ learning initiative, students can achieve “self-education, self-management, self-service, and common improvement”, so as to improve the teaching quality of this course, improve students’ clinical skills, promote the self-development of teachers and students, and realize the “winwin” of education.
Molecular Evidence of Anticancer Activity of Camel Milk Combined with Camel Urine
Authors:   College of Medicine, QU Health, Qatar University, Doha, Qatar, I Gupta , S Shanmuganathan ,   Department of Genetics, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman, H Al-Abri ,   Department of Genetics, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman, A Ouhtit ,   Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar
Published: October 2021

Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar
COVID-19: Epidemiology and Preventive Measures in Jiangsu Province, China
Authors:   Tongji University School of Medicine, Shanghai, China, Y Chen , J Liu ,   Center for Data Science, Peking University, Beijing, China, C Yang ,   Tongji University School of Medicine, Shanghai, China, A Zhang ,   Department of Medical Statistics, School of Medicine, Tongji University, Shanghai, China, Z Ai ,   Department of Medical Statistics, School of Medicine, Tongji University, Shanghai, China
Published: October 2021

Objective: To analyze the epidemiological features of coronavirus disease 2019 (COVID-19) in Jiangsu Province after starting level 1 response to major public health emergencies and assess the effectiveness of epidemic prevention and control measures took by the government. Methods: Individual information on all novel coronavirus pneumonia confirmed cases from January 10, 2020 to March 18th in Jiangsu was collected from the official website of Health Commission of Jiangsu province and its cities, Hubei Health Commission and the Chinese Health Commission. The trends in demographic and epidemiological characteristics of confirmed cases were estimated and the real time reproduction number (Rt) were calculated. Results: 631 COVID-19 cases were diagnosed in Jiangsu Province, covering 13 districts in Jiangsu. The confirmed cases consisted of imported cases (30.27%) and local transmitted cases (69.73%). 64.15% (238/371) local transmitted cases had reported a history of exposure to COVID-19 cases or patients with acute respiratory infection. Close contact with COVID-19 infectors in families, parties or some public places is the main transmission route for local transmission cases. The epidemic peak occurred from January 30 to February 4, then began to decline. The ratio of male to female cases was 1.22 to 1, and most patients were in the group of 30-70 years old, 49 patients (7.8%) with mild symptom and 572 patients (90.6%) with common type accounted for the majority. As of March 18, the cities with higher cumulative confirmed cases were Nanjing (93 cases, 15%), Suzhou (87 cases, 14%) and Xuzhou (79 cases, 12%). The Rt reached a peak of 4.05 (95%CI 2.27-6.34) on January 20, then began to decline. Rt was below the epidemic threshold (Rt<1) after January 31 and maintained a continuing downward trend. Conclusion: The epidemic preventive and control measures have contributed to interrupt local transmission of COVID-19 in Jiangsu Province, and the epidemic in Jiangsu Province was well under control in less than a month.
Drugs Shown to Inhibit SARS-CoV-2 in COVID-19 Disease: Comparative Basic and Clinical Pharmacology of Molnupiravir and Ivermectin
Authors:   Department of Medicine, Division of Hypertension and Clinical Pharmacology, Baylor College of Medicine, USA, AAL Ajayi
Published: October 2021

The pharmacology of anti-SARS-CoV-2 drugs, Molnupiravir (M) and repurposed Ivermectin (IV) were compared. The IC50 for the inhibition of viral replication were 0.3μM for M and 2.8μM for IV. Both drugs have good oral absorption, with M achieving peak plasma concentrations by 2 hours and IV by 5 hours. The plasma half life were 7 hours for M and 81-91 hours for IV. M inhibits viral replication inducing viral mutagenesis in RdRp, causing viral error catastrophe and viral extinction. IV affects viral cell entry, nuclear transport and inhibits replication via RdRp. IV has additional effect to suppress cytokine production through STAT-3 inhibition. M is a more potent antiviral drug and IV has a longer residence in the body. Their effects on RdRp and cytokine inhibition are potentially complimentary for anti-COVID-19 activity. Both IV and M should be compared in randomized controlled clinical trials, and the possibility of their combination for anti-SARS-CoV-2 antiviral actions, explored further.
A Glimpse From Behind the Mask: Thoughts from the Old Clinician
Authors:   210 Price Street, Walterboro, SC 29488-3229, USA, DW Strauss
Published: October 2021

This is an article/essay with focus on the question of the conflict between professional mystique and transparency in the clinician-patient relationship. Implied is the assumption that the professional “mask” influences treatment outcome and can distort or enhance the genuine nature of the relationship between those being served and those who serve them. The simple purpose of the question asked in the article is to stimulate discussion as to the relative utility of the professional mystique and professional transparency as to the degree that each influences treatment outcome and clinician satisfaction.
Impact of Reperfusion Therapy on the Levels of Endothelial Nitric Oxide Synthase in Patients with Acute Myocardial Infarction and Type 2 Diabetes Mellitus
Authors:   Kharkiv National Medical University. 4, Nauky Ave., Kharkiv 61022, Ukraine, Zaikina Т. S. , Minukhina D. V. , Rynchak P. I. , Tytova G. Yu. , Zolotaikina V. I.
Published: October 2021

The purpose of the study was to investigate the effect of reperfusion therapy on the levels of endothelial nitric oxide synthase in patients with acute myocardial infarction and concomitant type 2 diabetes mellitus. Materials and methods. The study involved patients with acute myocardial infarction, who were divided into groups depending on the presence of type 2 diabetes mellitus and the therapy performed for them: group 1 – 58 patients with acute myocardial infarction and diabetes mellitus who underwent percutaneous coronary intervention; group 2 – 15 patients with acute myocardial infarction and diabetes mellitus who underwent exclusively conservative treatment; group 3 – 40 patients with acute myocardial infarction without diabetes who underwent percutaneous coronary intervention; group 4 – 17 patients with acute myocardial infarction without diabetes, who underwent exclusively conservative treatment. Results and discussion. According to the obtained results, in patients with concomitant type 2 diabetes mellitus, significantly lower levels of endothelial nitric oxide synthase were revealed, compared with patients without disturbances in carbohydrate metabolism, which indicates deeper impairments of endothelial function against the background of hyperglycemia and insulin resistance. Analysis of the effect of reperfusion therapy showed a statistically significant increase in the level of endothelial nitric oxide synthase both in the group of patients with concomitant disorders of carbohydrate metabolism and without them, which indicates an improvement in the processes of endothelium-dependent dilation, regardless of the presence or absence of type 2 diabetes mellitus. The obtained results testify to the positive effect of percutaneous coronary intervention at the level of eNOS, which, in our opinion, will help to improve the vasodilating properties of vascular endothelium and prevent a complicated course of acute myocardial infarction. Conclusion. The patients with acute myocardial infarction and concomitant type 2 diabetes mellitus have significantly lower levels of endothelial nitric oxide synthase levels than patients without type 2 diabetes mellitus that indicates deep violations of endothelial function against background of metabolic changes associated with insulin resistance and hyperglycemia. Reperfusion therapy accelerates its restoration regardless of the presence or absence of type 2 diabetes mellitus
Insulin-Like Growth Factor-1 and Left Ventricle Remodeling in Patients with Hypertension with Abdominal Obesity
Authors:   LT Malaya National Institute of Therapy National Academy of Medical Sciences of Ukraine. 2-a, Lyubov Malaya Pr., Kharkiv 61039, Ukraine, Koval S. M. , Reznik L. A. , Starchenko T. G. , Penkova M. Yu.
Published: October 2021

The purpose of the work is to study the role of insulin-like growth factor-1 in the mechanisms of left ventricular remodeling in patients with arterial hypertension with abdominal obesity and arterial hypertension with normal body weight. Materials and methods. The study included 42 patients with arterial hypertension and abdominal obesity and 22 patients with arterial hypertension and normal body weight. All patients underwent general clinical laboratory and instrumental examination. The structural parameters of the heart were determined using echocardiographic studies. To assess the geometric rearrangement of the left ventricle, the relative thickness of its walls was calculated. Determination of the level of insulin-like growth factor-1 in serum was performed using enzyme-linked immunosorbent assay. Results and discussion. According to echocardiographic studies, left ventricular hypertrophy was diagnosed in 30 patients (71.4%) with arterial hypertension and obesity and in 9 (40.9%) patients with normal body weight (p <0.05). The advantage of hypertrophic types in the structural reconstruction of the heart and the formation of unfavorable types of geometry of the left ventricle in the presence of abdominal obesity in the subjects was found. It was found that in arterial hypertension with abdominal obesity, high levels of insulin-like growth factor-1 were found with normal geometry of the left ventricle, and with concentric hypertrophy and eccentric hypertrophy, a gradual probable decrease in this growth factor was observed and adhered to its comparison with the norm. The attention is drawn not only to the gradual decrease in insulin-like growth factor-1 from normal geometry to concentric and eccentric geometry, but also to the probable differences between this growth factor in concentric geometry and eccentric geometry, indicating the role of insulin-like growth factor-1 deficiency in cardiac remodeling. In normal weight hypertension, probable differences in this growth factor are obtained only between normal and eccentric left ventricular geometry. Сonclusion. Thus, the data obtained may indicate differences in the course of arterial hypertension, aggravated by abdominal obesity, in comparison with patients with hypertension with normal body weight. It is the association of arterial hypertension with abdominal obesity that causes a decrease in the synthesis of insulin-like growth factor-1, as a result of which there is an accelerated development of the pathological geometry of the left ventricle with the subsequent manifestation of heart failure. These results allow us to expand our understanding of the mechanisms of the formation of cardiac damage in patients with arterial hypertension and especially when it is combined with obesity
Functional State of Liver in Patients with Progressing Chronic Myeloid Leukemia
Authors:   National Scientific Center of Radiation Medicine of the National Academy of Medical Sciences of Ukraine. 119/121, Peremohy Ave., Kyiv 03115, Ukraine, Maikut-Zabrodskaya I. M.
Published: October 2021

Chronic myeloid leukemia is found in approximately 20% of newly diagnosed cases of leukemia in adults. In Europe and North America, chronic myeloid leukemia ranks third among leukemias (after acute leukemias and chronic lymphoblastic leukemia). The problem of diagnosis, treatment, rehabilitation and adaptation of patients with chronic myeloid leukemia is relevant, as there is a gradual increase in the incidence of this disease both in the world and in our country. Some progress has been achieved in the treatment of patients with oncohematological diseases, in particular chronic myeloid leukemia. Chronic myeloid leukemia is a clonal myeloproliferative disease in which as a result of specific translocation of chromosomal sites between 9 and 22 chromosomes, a khimeric BCR-ABL gene with tyrosine kinase activity is formed. The purpose of the study was to investigate the main biochemical parameters that characterize protein and pigment metabolism, the activity of key enzymes in patients with chronic myeloblastic leukemia at different stages of the disease for further prospects of optimizing diagnosis, predicting the course of the disease in clinical practice. Materials and methods. The functional state of liver in 77 patients at different stages of chronic myeloid leukemia was studied. All patients admitted to the hospital were examined with the use of clinical, laboratory, instrumental and special research methods, and were consulted by specialists of related specialties, if necessary. The main biochemical parameters that characterize protein and pigment metabolism, the activity of key enzymes in patients with chronic myeloid leukemia of peripheral venous blood was determined by the method of V. Menshikov (1987). Results and discussion. The content of biochemical parameters that characterize protein and pigment metabolism, the activity of key enzymes in patients with chronic myeloid leukemia has been studied. It was found that biochemical parameters that characterize protein and pigment metabolism, the activity of key enzymes in patients with chronic myeloid leukemia is associated with an increase in the studied indicator (p<0,05). The article discusses the possible causes and pathogenetic mechanisms of the identified changes. As the disease progressed the changes of protein, pigment and enzyme kinds of metabolism were revealed. The article discusses possible pathophysiological mechanisms of the identified changes. Conclusion. In patients with chronic myeloid leukemia, there is an imbalance in protein, pigment metabolism, and the activity of some liver enzymes. With the progression of chronic myeloid leukemia, the functional state of the liver deteriorates
Instrumental Impedance Measurement as a Component of an Objective Structured Clinical Examination to Determine Body Composition in Patients with Non-Communicable Diseases
Authors:   Poltava State Medical University. 23, Shevchenko St., Poltava 36000, Ukraine, Potiazhenko М. М. , Mintser О. P. ,   Shupyk National Healthcare University of Ukraine. 9, Dorogozhytskaya Str., Kyiv 04112, Ukraine, Nevoit G. V. ,   Poltava State Medical University. 23, Shevchenko St., Poltava 36000, Ukraine
Published: October 2021

The purpose of the study is to assess the clinical feasibility and indicators of instrumental impedance measurement in patients who are at various stages of the cardiovascular continuum, in order to increase the effectiveness of measures for the prevention and treatment of non-communicable diseases in Ukraine by improving the diagnosis and prevention of non-communicable diseases through the introduction of modern science-intensive technologies into medical practice. Materials and methods. An open, non-randomized controlled study was performed with the assessment of examination on a BF 500 body composition monitor (model HBF-500-E, Omron Healthcare, Japan) in 186 functionally healthy individuals (control; in 75 respondents of professional athletes (group K1), in 111 respondents – intern doctors (group K2)) and in 253 patients with non-communicable diseases (main group). The patients were divided into four subgroups (Pg1, Pg2, Pg3, Pg4) depending on the stage of the cardiovascular continuum. Results and discussion. Non-compliance with the norm of body composition was found in 83% of respondents in group K2 and in 100% of patients. 83% of people were deficient in muscle, 23% had preobesity, 6% were obese, and 5% had visceral obesity. Overweight by body mass index was in 30% of Pg1 patients, in 31% of Pg2 patients, in 30% of Pg3 patients, in 37% of Pg4 patients and obesity was in 32% of Pg1 patients, in 31% of Pg2 patients, in 25% of Pg3 patients, in 35% of Pg4 patients. Overweight in the percentage of fat was diagnosed in 17% of Pg1 patients, in 31% of Pg2 patients, in 21% of Pg3 patients, in 37% of Pg4 patients; obesity was in 37% of Pg1 patients, in 48% of Pg2 patients, in 56% of Pg3 patients, in 51% of Pg4 patients. Visceral obesity was diagnosed in 35% of Pg1 patients, in 56% of Pg2 patients, in 60% of Pg3 patients, in 77% of Pg4 patients. Deficiency of muscle percentage was found in 85% of Pg1 patients, in 91% of Pg2 patients, in 89% of Pg3 patients, and in 88% of Pg4 patients. Conclusion. Instrumental impedance measurement shows clinical significance and should become a mandatory method of Objective Structured Clinical Examination. The body composition of patients with non-communicable diseases is characterized by an increase in energy expenditure of the main metabolism, general and visceral obesity, muscle deficiency. The degree and number of cases of violation of body composition increases with the progression of the cardiovascular continuum
Criteria and Indicators of Dental Care Quality: State of Development and Usage
Authors:   Shupyk National Healthcare University of Ukraine. 9, Dorogozhytskaya Str., Kyiv 04112, Ukraine, Krut A. G.
Published: October 2021

Healthcare quality criteria and indicators allow the head of the health care facility to clearly orientate in the degree of achievement of targets and improvement of results for patients. Studies of approaches to the formation of criteria and indicators of quality in the conditions of real domestic clinical practice, in particular, dental, are isolated. At the same time, in Ukraine there are no clinical protocols of dental care based on evidence-based technologies, which contain clinical quality indicators. The purpose of the study was to conduct a research on approaches to the development and usage of criteria and indicators for the quality of dental care in dental health facilities. Materials and methods. Such materials were used in the study as work plans for 2010-2019, administrative documents (orders), maps of expert assessments, "Guidelines for quality", internal audit protocols (a total of 149 units) of the three regional health care institutions of the dental profile. Methods, which were used, are system and process approach, content analysis, comparative analysis, graphical method. Results and discussion. In each institution, criteria and quality indicators are developed and monitored at the level of the doctor, line managers, the head of the institution and the medical council. Line managers conduct expert quality assessment, generalized "models of end results" which are formed at the level of the head of the institution. Detailed sets of criteria for the quality of the dental care process, ancillary processes and quality management systems are formed. Quantitative evaluation of the corresponding results on a scale and individual percentages is carried out. In general, the set of quality criteria and indicators is excessive in number, which does not meet the quality criteria defined by the standards for quality management systems, it contains mainly indicators of traditional industry reporting. At the same time, the world's evidence-based technologies of dental practice contain clinical indicators that reflect the use of interventions that have a proven impact on the quality of dental care expected by the patient, and which ensure efficient use of resources. Conclusion. The introduction of evidence-based technologies in dental practice is appropriate to improve approaches to the development of quality criteria and indicators, monitoring of clinical processes and compliance audits should be used, expert assessment should be carried out in case of defects
Optimization of Local Anesthesia during Radical Maxillary Sinusotomy in Dental Patients
Authors:   Lviv Danylo Halytskyi National Medical University. 69, Pekarskaya St., Lviv 79010, Ukraine, Mokryk O. Ya. , Putʹko Z. P. ,   Lviv Regional Clinical Hospital. 7, Chernihivska St., Lviv 79000, Ukraine, Hychka A. M. ,   Lviv Danylo Halytskyi National Medical University. 69, Pekarskaya St., Lviv 79010, Ukraine,   Lviv Regional Clinical Hospital. 7, Chernihivska St., Lviv 79000, Ukraine, Zaharkiv A. M. ,   Lviv Regional Clinical Hospital. 7, Chernihivska St., Lviv 79000, Ukraine
Published: October 2021

The purpose of the study was to give a clinical evaluation of the effectiveness of endonasal blockade of the nasopalatine nerve in different ways during radical maxillary sinusotomy in dental patients. Materials and methods. Clinical observations were performed in 50 patients diagnosed with chronic odontogenic maxillary sinusitis. Radical maxillary sinusotomy was performed under local potentiated anesthesia. All patients underwent anesthesia on the maxilla according to classical methods. Patients, depending on the methods of endonasal blockade of the nasopalatine nerve, were divided into two clinical groups: the main (24 people) and the comparison group (26 people). Patients of the main group underwent endonasal blockade of the nasopalatine nerve at the site of its branch from the pterygopalatine ganglion. In patients of the comparison group, the blockade of this nerve was performed before its entry into the incisal canal. The effectiveness of anesthesia was evaluated for clinical and autonomic manifestations of pain stress. Results and discussion. During the removal of polyps and pathological granulations from the mucous membrane of the maxillary sinus in patients of the main group there was no pain, no emotional-motor and autonomic manifestations of pain stress, which confirmed the effectiveness of the endonasal method of anesthesia of the nasopalatine nerve. In patients of the comparison group during similar surgical manipulations the full effect of local anesthesia was achieved in 50.0% of cases (χ2 – 8.065, р = 0.005). These were patients who had hypopneumatized or moderately pneumatized types of maxillary sinuses. The rest of the patients during the operation had emotional – motor and autonomic manifestations of pain stress during the removal of pathologically altered mucous membrane located on the medial wall of the maxillary sinus. Conclusion. Complete anesthesia of the mucous membrane, maxillary sinus, regardless of the degree of its pneumatization is achieved during the usage of endonasal blockade of the nasopalatine nerve at the site of its branch from the pterygopalatine ganglion during radical maxillary sinusotomy in dental patients. Anesthesia of the nasopalatine nerve in the lower nasal passage, before its entry into the incisal canal, allows painless surgery only in patients with hypopneumatized maxillary sinuses and in most patients with moderate pneumatization
Comparative Assessment of the Possibility to Detect Early Signs of Joint Changes of the Temporomandibular Joint Using Cone-Beam Computed Tomography and Ultrasound Examination
Authors:   Belarusian State Medical University. 83, Dzerzhinski Ave., Minsk 220116, Republic of Belarus, Pohodenko-Chudakova I. O. , Krat M. I. ,   Association of oral and maxillofacial surgeons of the Republic of Belarus. 83, Dzerzhinski Ave., Minsk 220116, Republic of Belarus
Published: October 2021

The purpose of the study was to carry out a comparative analysis of the possibility of detecting early signs of articular changes in the temporomandibular joint with cone-beam computed tomography and ultrasound. Materials and methods. 20 patients with complaints of temporomandibular joint (16 women and 4 men) were examined who stated that the first symptoms associated with the joint appeared from 6 months to 1 year. Examination of patients with temporomandibular joint pathology included consultation of the patient by a dentist with the involvement of radiation research methods. During the examination by dentist, the odontogenic nature of the temporomandibular joint disorders was excluded or confirmed. Cone-beam computed tomography and ultrasound of the temporomandibular joint were performed in all patients according to standard methods. The comparative analysis was carried out on the basis of clinical examples with the conclusions of a specialist doctor in the field of radiation diagnostics and radiation therapy. Results and discussion. Pathology of the temporomandibular joint due to morphological and functional changes occurs in 40-75% of adult and occupies the third place in the list of the main nosological forms of dental diseases. At the same time, it is known that the use of radiation methods for diagnostics of surgical pathology in maxillofacial area of odontogenic and non-odontogenic etiology in the Republic of Belarus is provided by clinical protocols. A comparative analysis of the conclusion of patients who underwent cone-beam computed tomography and ultrasound of the temporomandibular joints allows us to conclude that ultrasound examination allows us to state early changes occurring in the temporomandibular joint. Therefore, the possibility of early diagnosis contributes to the appointment of an adequate and rational complex of therapeutic and rehabilitation measures which is important for stopping the progress of pathological changes. Also with the help of ultrasound, it is possible to establish signs of the development of various forms of osteoarthritis which are not detected on the cone-beam computed tomography at the initial stages of development. In addition, ultrasound allows to visualize changes occurring in soft tissues such as the articular disc which is not available for cone-beam computed tomography. Conclusion. The obtained results allow us to recommend ultrasound examination of the temporomandibular joint as a screening method and a method of the first level of examination in order to detect pathological changes from both bone and soft tissue structures of the joint as early as possible
Relationships between the Ukrainian Public's Awareness of Psychotropic Drugs, Stigmatizing People Taking Psychotropic Drugs and Stopping Psychotropic Drug Medication without Consulting with a Doctor
Authors:   University of Medicine in Prague. 1094, Duškova, 5-Smíchov, Praha 15000, Czech Republic, Khrypunova Tetiana
Published: October 2021

The purpose of the study was to outline possible relationships between public awareness of psychotropic drugs, stigmatization of people suffering from mental disorders and discontinuation of drugs without consultation with a doctor in Ukraine. Materials and methods. This study is based on the analysis of data obtained through an electronic questionnaire filled out by the Ukrainian public. Until April 2021 the questionnaire was freely available to everyone who wanted to take part in the survey. The questionnaire was distributed via an Internet link. Based on the obtained data, the respondents were divided into different categories depending on their education, profession (a medical worker was analyzed separately). Also, the respondents who had personal experience of using psychotropic drugs were interviewed especially deeply and in more details, depending on which group of drugs they used (antidepressants / antipsychotics / anxiolytics). The separate place in the study was given to identifying the general awareness of the Ukrainian public about correct and erroneous judgments about psychotropic drugs. Results and discussion. Based on the obtained data, main factors which are influencing people awareness of psychotropic drugs were identified, as well as the approximate percentage of citizens with erroneous judgments about psychotropic drugs. Thanks to the results of the questionnaire, the main possible reasons for the withdrawal of treatment with psychotropic drugs by patients without consultation with the attending physician were suggested (identified). Conclusion. It can be concluded from the obtained data that a person's awareness in the field of psychotropic drugs is most influenced by their own experience of their use. For this reason, the author would be interested to know how psychiatric patients are informed by their physicians. The author is aware that the amount of data obtained is not completely sufficient to create a significant picture of the general situation, but she hopes that the obtained data will still allow to get some idea of the situation as a whole. In conclusion, not only the obtained results in this study were outlined, but also possible further actions to obtain a more accurate picture of the situation were mentioned, and the topic of the next study was indicated in order to solve the identified problem
Information and Communication Competences of the Teacher in the Modern Medical Educational Medium
Authors:   Kharkiv National Medical University. 4, Nauki Ave., Kharkiv 61022, Ukraine, Zaytseva O. V. , Bondarenko M. A. , Rukin O. S.
Published: October 2021

The purpose of the work was to study the effectiveness of resources and services of the information and educational environment of the university, in particular, the information and educational portal Moodle in distance learning of students. Materials and methods. Two main aspects of the solution of the problem of informatization of education – computerization of educational institutions and acquisition of information and communication competences by scientific and pedagogical staff of universities – were considered. Results and discussion. The article outlines the challenges and possible directions of work in the second aspect, namely the need for academic educators to understand the State’s e-learning policy, how to plan their learning process using information and communication technology, the ability to use innovative pedagogical distance learning technologies and the ability to create new, in-house e-learning resources. The need for continuous professional development of professors in the application of innovative educational technologies was emphasized. Consideration was given to the experience gained in the implementation of the problem of improving the qualifications of scientific and pedagogical staff in the use of information and communication technologies and in the creation of an information and educational environment at the Kharkiv National Medical University through the establishment of the Distance Learning Centre of the Scientific and Training Institute for the Quality of Education of Kharkiv National Medical University. The possibilities of the Moodle information educational portal in the organization of distance learning are considered. One of the types of advanced training – the course on the basics of developing electronic learning courses was analyzed. The definition of an electronic learning course, its structure, main characteristics, an algorithm for creating, approbation and accreditation based on the experience of organizing distance learning at Kharkiv National Medical University are considered. Conclusion. The expediency of introducing distance learning courses into the educational process is argued and the experience of creating and testing a distance learning course in the discipline "Modern problems of biophysics" for students of the dental faculty of Kharkiv National Medical University is discussed
Effects of Breath-Holding Tests on PetCO2 and Arterial Blood Oxygenation in Men
Authors:   Cherkasy National University Named after Bohdan Hmelnitskiy. 81, Shevchenko Boulevard, Cherkasy 18031, Ukraine, Pytel A. A. , Kovalenko S. O.
Published: October 2021

To evaluate the state of external respiration system, breath-holding tests are usually used. However, there are few studies of the peculiarities of the gas exchange in breath-holding with previous hyperventilation. The purpose of the study was to analyze the dynamics of changes in the PetCO2 level and arterial blood oxygenation during breath-holding tests with and without previous hyperventilation in healthy young men. Materials and methods. The СО2 level was recorded in the side stream on the Datex Normocap capnograph (Datex, Finland). This value was recorded for 5 minutes at rest, 5 minutes after half-breath hold, for 5 minutes of regulated breathing with a frequency of 30 cycles per minute, 5 minutes after half-breath hold. The capnogram, atmospheric pressure level and humidity were used to assess the level of СО2 at the end of exhalation (PetCO2), respiratory rate, the ratio of inspiratory duration to expiratory duration (Rie). Statistical processing of the results was performed by parametric methods. According to the method of sigmoid deviation, three groups of individuals were distinguished by the PetCO2 level: I – PetCO2 < 32.7 mmHg, II – PetCO2 – 32.7-36.2 mmHg, III – PetCO2 > 36.2 mmHg. Results and discussion. Breath-holding during the test after hyperventilation was significantly greater than in the first attempt (62.99±3.31 s and 33.78±2.24 s, p <0.001). Visual qualitative and quantitative analysis of capnograms and graphs of arterial blood oxygenation revealed significant inter-individual features of the reactions of these indicators to tests. Therefore, changes in PetCO2 were compared depending on its initial level. After the breath-holding test, the PetCO2 levels on average during the 5-minute recovery reliably decreased in groups II and III compared with I. During the test with hyperventilation, a natural significant increase in its level of reactivity was registered, most pronounced in group III (-13.48 mmHg, p <0.001). After the second breath-holding, there was a decrease in PetCO2 compared to the level after the first breath-holding in all groups. However, the level of HbO2 in the tests differed only in group II. Thus, after a breath-holding test, individuals with relatively low PetCO2 did not have its decrease in contrast to those with relatively medium and high levels. The use of hyperventilation potentiates these reactions before breath-holding, and aligns their level after a long recovery period in different groups. Conclusion. The study shows that breath-holding tests without and after hyperventilation significantly affect the level of CO2 stress and arterial blood oxygenation; the breath-holding test after hyperventilation potentiates the decrease in PetCO2 and HbO2 in arterial blood by increasing breath-holding time. There are significant individual features in the reactivity of such physiological parameters