bluuebunny/crossref_metadata_2025 huggingface dataset:
Faktor yang Memengaruhi Tumbuh Kejar Anak Pascaoperasi Koreksi Defek Septum Ventrikel
Authors: Novianingrum Marcella Trixie Kartika , Priyatno Agus , Pratiwi Rina
Published: May 2023

Latar belakang. Penyakit jantung bawaan (PJB) merupakan penyebab utama gagal tumbuh. Gangguan hemodinamik akibat defek septum ventrikel (DSV) memberikan gejala yang menggambarkan derajat kelainan jantung. Operasi koreksi memperbaiki gangguan hemodinamik dan pertumbuhan. Penelitian sebelumnya melaporkan bahwa perbaikan pertumbuhan setelah operasi DSV bersifat multifaktorial. Tujuan. Untuk mengetahui faktor yang memengaruhi tumbuh kejar anak pascaoperasi koreksi DSV.Metode. Penelitian kohort retrospektif pada 59 anak paska 6 bulan operasi koreksi DSV. Data mengenai jenis kelamin, ukuran defek, derajat hipertensi pulmonal, usia saat operasi, dan derajat gagal jantung dicatat. Data dianalisis menggunakan SPSS versi 26.Hasil. Total sebanyak 59 data anak pascaoperasi koreksi DSV telah diperoleh dan 40 anak (67,8%) mencapai tumbuh kejar. Analisis bivariat menunjukkan bahwa ukuran defek, usia saat operasi, dan status gizi sebelum operasi memengaruhi tumbuh kejar paska operasi. Hasil tersebut dilanjutkan dengan analisis multivariat. Usia saat operasi merupakan faktor yang paling memengaruhi tumbuh kejar pascaoperasi DSV (p=0,038; RR 0,175; IK95%: 0,63-0,87). Nilai probabilitas anak usia 1-5 tahun untuk mencapai tumbuh kejar sebesar 0,204 (RR 1,09). Kesimpulan. Ukuran defek, status gizi sebelum operasi, dan usia saat operasi memengaruhi tumbuh kejar pascaoperasi DSV. Usia saat operasi merupakan faktor yang paling memengaruhi tumbuh kejar pascaoperasi koreksi DSV.
Kitabisa.com Sebagai Sebuah Sistem Sosio-Religio-Teknis Perspektif Maqashid al-Syari’ah
Authors: Ahsan Wildan Nadiyal , Maulana Diky Faqih
Published: May 2023

Perkembangan teknologi sekarang membuat semua kegiatan menjadi lebih mudah dilakukan dan lebih cepat dilakukan. Tak terkecuali kegiatan yang bersifat religius juga terkena dampak dari perkembangan teknologi, contohnya adalah bersedekah. Seiring dengan perkembangan zaman, khususnya penggunaan media online sebagai wadah untuk berdonasi menimbulkan suatu permasalahan dalam ranah religius. Muncul kalangan masyarakat yang menanyakan tentang keabsahan sistem donasi online dalam ranah agama khususnya agama Islam. Apakah sistem donasi tersebut sesuai dengan tujuan dan prinsip beragama. Tujuan dari penelitian ini adalah untuk menemukan dan menjelaskan tentang sistem donasi pada website Kitabisa.com apakah platform tersebut sesuai dengan tujuan dan prinsip beragama. Metode penelitian yang dipakai dalam penelitian ini adalah Kualitatif Deskriptif. Hasil dari penelitian ini mengungkapkan bahwa Kitabisa.com dalam kegiatannya sudah sesuai dengan kaidah maqashid al-syariah dan juga memenuhi akad fiqh muamalah yang menjadikan sistem ini aman dan sesuai dengan syariat islam, tidak bertentangan dengan hukum syara’. Dan Sebagai sebuah aplikasi, Kitabisa.com sudah dapat dikatakan user-friendly dan sudah mengakomodasi faktor teknis-manusia-dan religi.
Urgensi Pemahaman Bahasa Arab dalam Mempelajari Agama Islam di Indonesia
Authors: Agustini Agustini
Published: May 2023

Arabic is a foreign language in Indonesia, most of those who study Arabic in Indonesia are predominantly Muslim. Arabic is one of the languages of communication and also the language of religion. Some people in Indonesia study Arabic only as a science of language while Arabic is associated with the language of religion because the population in Indonesia is predominantly Muslim, therefore most Muslims in Indonesia learn Arabic to make it easier to understand the contents of the holy book Al-Qur'an 'an and to explore the religious side. The type of research used is descriptive qualitative which will clearly narrate the data obtained in the field. This study aims to determine the importance of understanding the Arabic language for Muslim communities in Indonesia. Learning Arabic requires carefulness and seriousness since the tools of knowledge acquired in Arabic will not be easily understood in a short learning time. The holy book of Islam is the Koran written in Arabic. Therefore, one who wants to understand Islam well is highly recommended to study Arabic seriously as the most impossible thing he can do. That is because by learning Arabic, he will be able to understand every meaning of Islamic teachings contained in the holy book Al-Qur'an which has been written in Arabic. Al-Qur'an and hadith are the main sources of implementing Islamic teachings, Thus, if a Muslim understands Arabic well enough then understanding both Qur'an and hadith will definitely be easier and can also prevent him from misunderstanding or misinterpreting the content. Therefore, in Islamic Education, Arabic language education is very important to be taught. Arabic is not only the language of Muslims but the language that Allah has chosen as the language of the Qur'an. The urgency of learning Arabic is very important in Islamic education in order to be able to understand the teachings contained in Islamic education.
Establishment and Verification of a Nomogram for Predicting the Probability of New-Onset Atrial Fibrillation After Dual-Chamber Pacemaker Implantation
Authors: Yang Ying , Lu Jiangting , Xiong Cui , Shen Zhida , Shen Chao , Tong Jinshan , Jiang Jiangfen , Fu Guosheng , Xu Fen
Published: May 2023

Background

This study aims to establish and validate a nomogram as a predictive model in patients with new-onset atrial fibrillation (AF) after dual-chamber cardiac implantable electronic device (pacemaker) implantation.

Methods

A total of 1120 Chinese patients with new-onset AF after pacemaker implantation were included in this retrospective study. Patients had AF of at least 180/minute lasting 5 minutes or longer, detected by atrial lead and recorded at least 3 months after implantation. Patients with previous atrial tachyarrhythmias before device implantation were excluded. A total of 276 patients were ultimately enrolled, with 51 patients in the AF group and 225 patients in the non-AF group. Least absolute shrinkage and selection operator (LASSO) method was used to determine the best predictors. Through multivariate logistic regression analysis, a nomogram was drawn as a predictive model. Concordance index, calibration plot, and decision curve analyses were applied to evaluate model discrimination, calibration, and clinical applicability. Internal verification was performed using a bootstrap method.

Results

The LASSO method regression analysis found that variables including peripheral arterial disease, atrial pacing-ventricular pacing of at least 50%, atrial sense–ventricular sense of at least 50%, increased left atrium diameter, and age were important predictors of developing AF. In multivariate logistic regression, peripheral arterial disease, atrial pacing-ventricular pacing of at least 50%, and age were found to be independent predictors of new-onset AF.

Conclusion

This nomogram may help physicians identify patients at high risk of new-onset AF after pacemaker implantation at an early stage in a Chinese population.
Authority over power in English learner accountability policies: Maintaining a national role within a context of local control
Authors: Flores Nelson , Saldivar Garcia Erica , Edgerton Adam
Published: May 2023

Pushback against the perceived federal overreach into educational reform has led to renewed calls for a return to local control of schools. In contrast to this general trend, there has continued to be a strong national role for English learner (EL) accountability policies related to EL identification, monitoring and reclassification processes. In this article, we seek to bring attention to the historical development and contemporary instantiation of these EL accountability policies. The general accountability system has typically focused on coercive strategies connected to rewards and sanctions. In contrast, the EL accountability system has typically focused on harnessing the expertise of research to provide increasingly specific guidelines for how to meet federal mandates related to supporting students officially classified as ELs. This approach may help explain how national actors have been able to maintain an active role in shaping these policies without being perceived as a threat to local control. We conclude with implications for national educational actors interested in using authority to shape other areas of educational policy as well as possible limitations of this approach.
Propuesta teórico-metodológica para decolonizar la enseñanza de la historia
Authors: Sher Benjamin Rafael , Sáez-Rosenkranz Isidora
Published: May 2023

La historia como disciplina escolar es una de las materias más sensibles en la construcción de los relatos hegemónicos (nacionales y occidentales). Su enseñanza está atravesada por un legado histórico institucional que se ha configurado en distintos niveles una enseñanza colonial moderna, homogeneizando las narrativas y, en definitiva, transmitiendo el sesgo eurocéntrico. Ante este diagnóstico, en el presente texto realizamos una propuesta teórico-metodológica para decolonizar la enseñanza de la historia. Para ello, en primer lugar, abordamos el papel de la enseñanza de la historia en la formación de la ciudadanía e indagamos en las posibilidades que ofrece la mirada decolonial para la ciudadanía actual. A continuación, exploramos teóricamente las posibilidades de una historia decolonial y enfatizamos en los aportes que esta perspectiva ofrece. Finalmente, articulamos una serie de propuestas metodológicas concretas para incluir el enfoque decolonial en la enseñanza de la historia.
Experiences of Prejudice, Stereotype, and Discrimination Exposure of Secondary School Students
Authors: Guleryuz Onur , Kilcan Bahadir
Published: May 2023

Although being exposed to prejudice, stereotype and discrimination reduces the self-esteem and quality of life of individuals, the effect of it on secondary school students is not fully understood. This study aimed to reveal the meaning, structure and essence of secondary school students' experiences of being exposed to prejudice, stereotype and discrimination. The present study was conducted with phenomenology, one of the qualitative research designs. Maximum variety and criterion sampling from one of the purposive sampling strategies were used to determine the participants. In this study, research participants consisted of 12 students studying in 7th and 8th grades in two public schools in Ankara, Turkiye. Research data were collected by semi-structured interview method. Within the scope of this study, 24 in-depth interviews were conducted with each participant twice. In data analysis, phenomenological analysis, bracketing, listing key phrases, developing sets of meanings, textural description, structural description, and extracting essences, were used. The findings showed that the students exposed to prejudice, stereotyping and discrimination suffered from self-esteem and self-confidence, their academic motivation decreased, they developed sympathy for the in-group and antipathy to the out-group and they were in search of equality and justice.
Investigation of Prospective Mathematics Teachers’ Proof Completion Processes Supported By Key Ideas
Authors: Yesilyurt Cetin Aysun , Dikici Ramazan
Published: May 2023

The aim of this research was to examine prospective mathematics teachers’ completion processes of mathematical proofs supported by key ideas in the field of abstract algebra. Prospective teachers were asked to complete the parts of a proof left incomplete using those key ideas. It was decided together with three academics who are experts in the field of algebra which theorems to use and which proof sections to leave missing in the proof completion form. The proof completion form consisted of 5 proofs and was applied to 5 participants. The participants' processes of completing the proofs were evaluated in semi-structured interviews supported by the think-aloud method. Interviews were recorded by video and transcribed, and descriptive analysis was performed. The findings obtained were analyzed with think-aloud protocols. According to the results, key ideas can be said to play an active role in the proof process and the teaching of proof. In addition, developing activities consisting of proofs supported by key ideas can contribute to prospective teachers’ abilities to prove without memorization and internalize proof processes.
Detection of Blastocystis Hominis by Method of Cultivation in The Feces of Orphanage Children in Pekanbaru, Riau Province, Indonesia
Authors: Maryanti Esy , Lesmana Suri Dwi , Firja Wira , Devlin Muhammad , Mislindawati Mislindawati , Siagian Forman Erwin
Published: May 2023

Background: Blastocystis hominis is an intestinal protozoan that can infect humans and animals. The distribution coverage is very wide and is transmitted through the fecal-oral route. The incidence of blastocystosis due to Blastocystis hominis is higher in developing countries because it is associated with poor hygiene practice, inadequate sanitation, close contact with pets domesticated animals and or contaminated food. Blastocystis hominis infection can cause clinical manifestations, from asymptomatic to chronic diarrhea, depending on the Blastocystis subtype and the patient's immune system. brief background of the topic and significance of the study.Objective: The aim of this study was to detect and determine the incidence of Blastocystis hominis infection in the feces of children at the Pekanbaru Orphanage using the culture method.Methods: The sample is the feces of children from nine orphanages in Pekanbaru. Detection of Blastocystis by the modified Jone's Medium culture method but using sheep's serumResults: A total of 95 children's stool samples were examined from 9 orphanages in Pekanbaru, it was found that 63 children (66.3%) were positive for Blastocystis hominis using the culture method, positive Blastocystis hominis was found more in boys (58.7%%) than girls, and based on age group, 6-12 years were found to be the age group with the most infection (84.1%). Generally, the source of drinking water in orphanages is refilled drinking water and all orphanages have cats as pets, and a few have chickens, birds, and goats as petsConclusion: High incidence of Blastocystis hominis can be detected in the feces of Pekanbaru orphanage children using the culture method.
Effects of Fermented Tempeh Using Rhizopus oligosporus and Lactobacillus rhamnosus GG on Body Weight, Lee Index, High Sensitivity C Reactive Protein and Lipid Profile of Obese Rats
Authors: Zahra Fatih Az , Fulyani Faizah , Maharani Nani , Anjani Gemala , Noer Etika Ratna
Published: May 2023

Background: Tempeh is a fermented soybean containing isoflavones that shows good benefits again obesity. Co-fermentation of tempeh using  Lactobacillus rhamnosus GG could increase the bioavailability of isoflavones.Objective: This study aimed to determine the effect of co-fermented tempeh using Lactobacillus rhamnosus GG (tLGG) on body weight (B.W.), Lee Index, high sensitivity C Reactive Protein (hs-CRP), and lipid profile of obese rats. Total flavonoid and genistein were also measured.Methods: Male Sprague Dawley rats (n=36, 200-to-215-gram, age eight weeks) were orally administered high fat and high sucrose diet (HFHS diet) for two weeks to induce obesity. After obesity was confirmed by checking Lee Index, rats were divided into six group and administered orally standard diet (normal control), HFHS diet (negative control), HFHS diet and 120 mg/kg B.W./day-orlistat (positive control), HFHS diet and 60 mg/kg B.W./day standard tempeh  with Rhizopus oligosporus (tS), HFHS diet and 60 mg/kg B.W./day tLGG, HFHS diet and 120 mg/kg B.W./day tLGG for four weeks. Body weight, Lee Index, hs-CRP, and lipid profile were analyzed. Total flavonoid and genistein were analyzed.Results: 120 mg/kg B.W./day tLGG group exhibited significantly lower body weight gains, Lee Index, hs-CRP, triglyceride, total cholesterol, LDL, and higher HDL compared to negative control and tS group (p<0,001), however, positive control group exhibited lower body weight gains compared to tLGG group (p<0,001). Nevertheless, tLGG group exhibited lower Lee Index compared to positive control group.   tLGG showed higher flavonoid and genistein level than tS.Conclusion: Administration of 120 mg/kg B.W./day tLGG showed significantly lower Lee Index compared to all groups given HFHS diet, however, positive control group showed lower body weight gains compared to tLGG group. tLGG also improved hs-CRP and lipid profile two times better than negative control group. tLGG increased total flavonoids and genistein level.
Searching for Consistency in Attendance Data Recording, Reporting, and Utilization in the USA
Authors: Graczyk Patricia A. , Gentle-Genitty Carolyn , Humm Patnode Amber , Moulton Sara E.
Published: May 2023

According to the United States Department of Education (USDOE), 16% or over eight million kindergarten through twelfth grade students in the US missed 10% or more school days during the 2017−2018 school year. This is approximately 18 of 180 days required. We know this because schools are mandated to report their attendance data to their respective states and to the USDOE. There are concerns around accuracy and consistency because each state is allowed to compile data in their own way and report only select metrics to the USDOE to comply with federal guidelines. The consistency on federal metrics, nonetheless, allows for similar analyses at the federal and state levels and comparisons across states. To best understand what is reported, we report on data compiled by the National Center for Education Statistics (NCES) housed in the Institute of Education Sciences, the science branch of the USDOE, and describe how attendance data are collected, reported, and used at the national level. We share similar findings for two representative US states − Connecticut and Indiana − to highlight similarities and differences between them, and their “best practices.” Key results from these multiple levels of analyses are then discussed, with the goal of informing research, practice, and policy related to school attendance, so that students of all ages and from all backgrounds are provided the opportunity to obtain optimal benefits from schooling throughout their school careers.
Examining the role of writing proficiency in students’ feedback literacy development
Authors: Zhou Yu , Yu Shulin , Liu Bihao , Jiang Lianjiang
Published: May 2023

While student feedback literacy has received increasing attention in second language education, little is known about the role of writing proficiency in the development of student feedback literacy. This qualitative study examined the characteristics of high and low English writing proficiency (i.e., HP, LP) students’ feedback literacy in second language (L2) writing and identified the factors that shape these students’ feedback literacy. This study involved five LP and five HP students with data collected from semi-structured interviews, students’ drafts, teacher’s written corrective feedback and peer feedback. The results found that both the LP and HP students were cognitively prepared in terms of appreciating feedback value with distinct self-orientation in feedback process and emotionally ready in regulating their affect for gains from handling feedback. Yet, the LP students were found less prepared to benefit from their current feedback practice due to their passive perspective of learner roles. By contrast, HP students displayed their preparedness featured by proactive learner roles in feedback process, well-developed judgement criteria and broader revisions. The internal consistency across dimensions of feedback literacy was also identified for HP students but not for LP students. Factors contributing to the disparity include students’ perception of their writing proficiency, course engagement and their self-regulation ability. Pedagogical implications on enhancing feedback literacy for students with varied writing proficiency levels are provided.
Effective deep learning classification for kidney stone using axial computed tomography (CT) images
Authors: Sabuncu Özlem , Bilgehan Bülent , Kneebone Enver , Mirzaei Omid
Published: May 2023

Introduction

Stone formation in the kidneys is a common disease, and the high rate of recurrence and morbidity of the disease worries all patients with kidney stones. There are many imaging options for diagnosing and managing kidney stone disease, and CT imaging is the preferred method.

Objectives

Radiologists need to manually analyse large numbers of CT slices to diagnose kidney stones, and this process is laborious and time-consuming. This study used deep automated learning (DL) algorithms to analyse kidney stones. The primary purpose of this study is to classify kidney stones accurately from CT scans using deep learning algorithms.

Methods

The Inception-V3 model was selected as a reference in this study. Pre-trained with other CNN architectures were applied to a recorded dataset of abdominal CT scans of patients with kidney stones labelled by a radiologist. The minibatch size has been modified to 7, and the initial learning rate was 0.0085.

Results

The performance of the eight models has been analysed with 8209 CT images recorded at the hospital for the first time. The training and test phases were processed with limited authentic recorded CT images. The outcome result of the test shows that the Inception-V3 model has a test accuracy of 98.52 % using CT images in detecting kidney stones.

Conclusions

The observation is that the Inception-V3 model is successful in detecting kidney stones of small size. The performance of the Inception-V3 Model is at a high level and can be used for clinical applications. The research helps the radiologist identify kidney stones with less computational cost and disregards the need for many experts for such applications.
Concise review on the combined use of immunocapture, mass spectrometry and liquid chromatography for clinical applications
Authors: Massonnet Philippe , Grifnée Elodie , Farré-Segura Jordi , Demeuse Justine , Huyghebaert Loreen , Dubrowski Thomas , Dufour Patrice , Schoumacher Matthieu , Peeters Stéphanie , Le Goff Caroline , Cavalier Etienne
Published: May 2023

Immunocapture is now a well-established method for sample preparation prior to quantitation of peptides and proteins in complex matrices. This short review will give an overview of some clinical applications of immunocapture methods, as well as protocols with and without enzymatic digestion in a clinical context. The advantages and limitations of both approaches are discussed in detail. Challenges related to the choice of mass spectrometer are also discussed. Top-down, middle-down, and bottom-up approaches are discussed. Even though immunocapture has its limitations, its main advantage is that it provides an additional dimension of separation and/or isolation when working with peptides and proteins. Overall, this short review demonstrates the potential of such techniques in the field of proteomics-based clinical medicine and paves the way for better personalized medicine.
Investigation of hybrid fractionalq-integro-difference equations supplemented with nonlocalq-integral boundary conditions
Authors: Alsaedi Ahmed , Ahmad Bashir , Al-Hutami Hana , Alharbi Boshra
Published: May 2023

In this article, we introduce and study a new class of hybrid fractionalqq-integro-difference equations involving Riemann-Liouvilleqq-derivatives, supplemented with nonlocal boundary conditions containing Riemann-Liouvilleqq-integrals of different orders. The existence of a unique solution to the given problem is shown by applying Banach’s fixed point theorem. We also present the existing criteria for solutions to the problem at hand by applying Krasnoselskii’s fixed point theorem and Leray-Schauder’s nonlinear alternative. Illustrative examples are given to demonstrate the application of the obtained results. Some new results follow as special cases of this work.
Explicit Sato–Tate type distribution for a family of
K
⁢
3
K3
surfaces
Authors: Saad Hasan
Published: May 2023

In the 1960s, Birch proved that the traces of Frobenius for elliptic curves taken at random over a large finite field is modeled by the semicircular distribution (i.e. the usual Sato–Tate for non-CM elliptic curves). In analogy with Birch’s result, a recent paper by Ono, the author, and Saikia proved that the limiting distribution of the normalized Frobenius traces

A
λ

⁢

(
p
)

{A_{\lambda}(p)}

of a certain family of

K
⁢
3

{K3}

surfaces

X
λ

{X_{\lambda}}

with generic Picard rank 19 is the

O
⁢

(
3
)

{O(3)}

distribution. This distribution, which we denote by

1

4
⁢
π

⁢
f
⁢

(
t
)

{\frac{1}{4\pi}f(t)}

, is quite different from the semicircular distribution. It is supported on

[

-
3

,
3
]

{[-3,3]}

and has vertical asymptotes at

t
=

±
1

{t=\pm 1}

. Here we make this result explicit. We prove that if

p
≥
5

{p\geq 5}

is prime and

-
3

≤
a
<
b
≤
3

{-3\leq a<b\leq 3}

, then

|

#
⁢

{

λ
∈

𝔽
p

:

A
λ

⁢

(
p
)

∈

[
a
,
b
]

}

p

-

1

4
⁢
π

⁢

∫
a
b

f
⁢

(
t
)

⁢

𝑑
t

|

≤

98.28

p

1
/
4

.

\biggl{\lvert}\frac{\#\{\lambda\in\mathbb{F}_{p}:A_{\lambda}(p)\in[a,b]\}}{p}-%
\frac{1}{4\pi}\int_{a}^{b}f(t)\,dt\biggr{\rvert}\leq\frac{98.28}{p^{1/4}}.

As a consequence, we are able to determine when a finite field

𝔽
p

{\mathbb{F}_{p}}

is large enough for the discrete histograms to reach any given height near

t
=

±
1

{t=\pm 1}

. To obtain these results, we make use of the theory of Rankin–Cohen brackets in the theory of harmonic Maass forms.
The inverse scattering problem for an inhomogeneous two-layered cavity
Authors: Ye Jianguo , Yan Guozheng
Published: May 2023

In this paper, we consider the inverse scattering problem of identifying a two-layered cavity by
internal acoustic measurements under the condition that the interior interface has a mixed transmission boundary condition. We focus on the mathematical analysis of recovering the shape of the interior interface by using the linear sampling method, including reconstructing the surface conductivity by the same measurements.
Approximate Lipschitz stability for phaseless inverse scattering with background information
Authors: Sivkin Vladimir N.
Published: May 2023

We prove approximate Lipschitz stability for monochromatic phaseless inverse scattering with background information in dimension

d
≥
2

{d\geq 2}

. Moreover, these stability estimates are given in terms of non-overdetermined and incomplete data. Related results for reconstruction from phaseless Fourier transforms are also given. Prototypes of these estimates for the phased case were given in
[R. G. Novikov,
Approximate Lipschitz stability for non-overdetermined inverse scattering at fixed energy,
J. Inverse Ill-Posed Probl. 21 2013, 6, 813–823].
Comparative analysis of 128 × 40 Gbps DQPSK based DWDM long-haul system using various dispersion compensation techniques
Authors: Ghera Jaswinder Singh , Sharma Vikrant
Published: May 2023

In this research article, we have made the comparative performance analysis towards the ultra-transmission capacity of 5.12 Tbps for DWDM long-haul system using spectrally efficient multilevel DQPSK modulation format under the influence of Kerr’s nonlinearities with DCF based distributed, pre-, post and two types of symmetrical compensation techniques. The performance evaluation criteria of the proposed system for 50 GHz frequency spacing between the adjacent channels at 0 dBm launched power and various transmission distances with the increment of 2400 km are kept as BER, Q-factor and eye-diagrams. We have used Gaussian filters (GFs) at both ends before multiplexing and after de-multiplexing for ensuring channel severance to elude the cross-talk and inter-symbol interference. It is observed that the distributed compensation technique outperformed rest of the techniques and supported maximum coverage distance towards 19,200 km for Q-factor of 6.96 and corresponding BER of 1.72E-12 in comparison to sym-1 for 14,400 km at Q-factor of 6.95 with BER of 1.77E-12 and sym-2 for 9600 km at Q-factor of 7.13 with BER of 4.83E-13 whereas both pre- and post-compensation techniques supported 7200 km at Q-factor of 7.21 with BER of 2.71E-13 and Q-factor of 7.18 for BER of 3.53E-13, respectively.
Adiponectin–leptin ratio as a marker of cardio-metabolic risk in Indian children and youth with type 1 diabetes
Authors: Shah Nikhil , Khadilkar Anuradha , Oza Chirantap , Bhor Shital , Ladkat Dipali , Gondhalekar Ketan , More Chidvilas , Khadilkar Vaman
Published: May 2023

Objectives

Adiponectin/leptin ratio (ALR) is a promising novel marker of cardio-metabolic risk in patients with metabolic syndrome. Our aim was to study the association of adiponectin-leptin ratio with markers of obesity and adiposity and also to assess its usefulness as a marker of increased cardiometabolic risk (CMR) in Indian children and youth with type 1 diabetes mellitus.

Methods

This observational study included 79 children and youth with type 1 diabetes (T1DM) (10–21 years) having disease duration>6 months. Demographic data and laboratory findings were obtained from patients’ records. Patients with ALR<1 were categorised as having increased CMR and those with ALR>1 were categorised as having no CMR.

Results

ALR showed a significant negative correlation with body mass index (BMI), waist and hip circumference and body fat percentage (p<0.05). Body fat percentage was the single most important predictor of ALR. Children and youth with increased CMR had higher weight, BMI, waist and hip circumferences and body fat percentage as compared to those with no CMR (p<0.05). In T1DM children with dyslipidemia, ALR was significantly lower as compared to those without dyslipidemia (p<0.05).

Conclusions

ALR may be a useful marker for adiposity and increased cardiometabolic risk in Indian children and youth with type 1 diabetes mellitus.
Digitális nudge-ok hatása a szolgáltatott szoftver felhasználókra
Authors: Gyulai Zsófia
Published: May 2023

A TANULMÁNY CÉLJA
A kutatás célja feltárni, hogy az online felhasználók miként és mennyire észlelik a digitális nudge-okat, valamint, hogy milyen hatással vannak a felhasználói döntéseikre. A kutatás további célja a digitális nudge-okat alkalmazó vállalat és a felhasználók kapcsolatának tanulmányozása.
ALKALMAZOTT MÓDSZERTAN
A digitális nudge-ok konverziós képessége és kilépési arányra gyakorolt hatása egy integrált webanalitikai szolgáltatott szoftver példáján keresztül, a webanalitikai adatok másodlagos elemzésével került vizsgálatra. A nudge-ok észlelése és hatása miatt szolgáltatott szoftver felhasználókkal készített csoportos interjú készült különböző szolgáltatott szoftverek felhasználóival. Az interjúkkal a kutatás mélyebb betekintést ad arról, mennyire vannak tudatában a felhasználók az egyes nudge-ok alkalmazásának, valamint mennyire zavaró az egyes nudge-típusok alkalmazása számukra.
LEGFONTOSABB EREDMÉNYEK
Az eredmények azt mutatják, hogy a szolgáltatott szoftver felhasználókra pozitív hatással vannak a nem manipulatív ösztönzések, azonban a különböző digitális nudge-ok érzékelésének vizsgálata nagy eltéréseket mutatott. A kutatás alapján a veszteségelkerülési torzításon alapuló nudge-ok eredményezik a legnagyobb konveziót, azonban a legtöbb negatív reakciót is ez a kategória váltotta ki. Az eredmények szerint a digitális nudge-ok alkalmazása szignifikánsan növeli a konverziót a kilépési arány csökkentése nélkül.
GYAKORLATI JAVASLATOK
Bár számos tudományterületen születtek már kutatások a nudge-okról, a digitális nudge kutatások még gyerekcipőben járnak. A témán és a módszertanon túl a szolgáltatott szoftverek vizsgálata is újdonság erővel bír, mivel egy rohamosan fejlődő szektor, amely előszeretettel alkalmazza a digitális nudge-okat.
A tanulmány javaslatot tesz a digitális nudge-ok optimális használatára. A kutatás egy, a gyakorlatban is könnyedén használható módszertant alkalmaz, a webanalitikai adatok elemzését, így a gyakorlati szakemberek számára útmutatóként szolgálhat az általuk alkalmazott nudge-ok vizsgálatához.
Slow és turizmus - a kisvárosfejlesztési alternatíva!?
Authors: Piskóti István , Marien Anita , Papp Adrienn , Nagy Katalin
Published: May 2023

A TANULMÁNY CÉLJA
A kisvárosok fejlődési lehetőségei, versenyképessége, lakóhelyi vonzereje megerősödőben van, s ezáltal sajátos szerep adódik számukra a település-rendszerben (Cox-Longlands 2016.). E szerep ígéretes, sikeres formálását segítheti a slow alapú városfejlesztési filozófia és gyakorlat. (Osbaldiston 2013, Birkner és tsai 2017) A slow mozgalom leginkább a hagyományok jelentőségét, a minőséget, a környezetbarát mezőgazdasági termelést, illetve a helyi termékeket hangsúlyozza. Az alapelveikhez tartoznak továbbá az egészséges életmód, a helyi közösségek aktivitása, különösen a rájuk vonatkozó döntések meghozatalában. Célunk a slow filozófia, s az abba integráltan beépülő slow turizmus bemutatása és alkalmazása a települések jövőépítésében.
ALKALMAZOTT MÓDSZERTAN
A kisváros-marketing kutatási program keretében 2020 őszén primer kutatást végeztünk a magyar 5000 és 20000 fő lakost számláló kisvárosok körében. Kisvárosok vezetői kérdeztük, hogy miként definiálják, hogyan élik meg a kisvárosi létet, hogyan ítélik meg adottságaikat, szerepüket a településrendszerben, milyen problémákkal küzdenek. A téma aktualitását és fontosságát mutatja a magasnak tekinthető válaszadási arány.
LEGFONTOSABB EREDMÉNYEK
A kisvárosok körében készült primer vizsgálati eredményeink szerint a turizmus kiemelten jelenik meg a településfejlesztési tervekben. A kisvárosok slow turizmusa igazi értékeket teremthet (Desalvo-Calzatti 2017), egyrészt a sokféle motivációjú, sok célcsoportot kielégítő, jelentős turistaforgalmú, korábban túlturizmussal küzdő nagyvárosi desztinációk gyógyító alternatívája, másrészt a turistaforgalomból eddig kimaradó, annak perifériáin megjelenő területek számára fenntartható, turizmusépítő perspektívát jelent (Pécsek 2008).
GYAKORLATI JAVASLATOKAT
Számos példa mutatja, hogy a slow filozófia a helyi identitásra, elégedettségre épülő, a helyi erőforrásokat fenntartható módon mozgató településfejlesztési alternatíva. Tanulmányunkban három olyan kezdeményezést mutatunk be, ahol a slow filozófia sikeresen alkalmazásra került a településfejlesztésben.
Köszönetnyilvánítás: "A tanulmány az EFOP-3.4.3-16-2016-00015 számú „Főnix ME” - Megújuló Egyetem Felsőoktatási intézményi fejlesztések a felsőfokú oktatás minőségének és hozzáférhetőségének együttes javítása érdekében című projekt Oktatási Innováció (2. részprojekt) projektelem keretén belül, annak támogatásával készült."
Postactivation Potentiation for Muay Thai Kicking Performance
Authors: Brown Lee , Doyle Gary , Bruce-Low Stewart , Domingos Silvino , Anthony Karl , Rowan Fionn , Galbraith Andy
Published: May 2023

Brown, L, Doyle, G, Bruce-Low, S, Domingos, S, Anthony, K, Rowan, F, and Galbraith, A. Postactivation potentiation for Muay Thai kicking performance. J Strength Cond Res 37(10): 2032–2037, 2023—The purpose of this study was to investigate the effects of postactivation potentiation (PAP) on Muay Thai kicking performance based on 3 different rest intervals. Aiming to quantify and indicate timing protocols for conditioning coaches when training athletes using PAP. 17 male (25.3 ± 3.6 years old; 179.3 ± 2.3 cm; 78.0 ± 5.2 kg), experienced Muay Thai fighters completed a standardized warm-up, including a 10-minute cycle on the Wattbike at 60 watts and 30 body mass squats for a dynamic stretch. Subjects then completed a baseline test by striking a PowerKube using the roundhouse and Teep kick techniques. PAP exercise consisted of 4 squat repetitions to maximum effort, followed by a rest period of 2, 5, or 8 minutes. Subjects then struck the PowerKube again using the roundhouse and Teep kick techniques. Rest periods were presented in a randomized order on separate days, with 72 hours between conditions. The level of significance was set at α = 0.05. Significant increases in both roundhouse (χ2(3) = 38.51, p < 0.05) and Teep kick (χ2(3) = 26.33, p < 0.05) striking power were observed when compared with baseline. For the roundhouse kick, significant differences and large effect sizes were present between all conditions except baseline and 2-minute rest. For the Teep kick, significant differences and large effect sizes were present between baseline and 5-minute rest and baseline and 8-minute rest. This indicates that PAP with 5- or 8-minute rest increased roundhouse and Teep kick power. This research reports that a PAP stimulus from a 4RM squat exercise, followed by a 5- or 8-minute rest period, enhances kick power in trained Muay Thai fighters. This technique provides a readily available, time-efficient method to enhance performance that can be built into the warm-up procedure of athletes before training or competition.
Multilevel Factors Influencing Interruptions in PrEP Use Among Young Women in Siaya County, Kenya
Authors: Perry Brian , Molokwu Nneka , Agot Kawango , Ngoje Duncan Ochieng , Strack Robert , Corneli Amy
Published: May 2023

Young women in sub-Saharan Africa continue to be disproportionately at risk for HIV. Oral pre-exposure prophylaxis (PrEP) can reduce women's HIV risk when taken daily throughout their “seasons of risk”. We used photovoice to describe community views on factors influencing interruptions in PrEP use among young cisgender women in Siaya County, Kenya. Through group discussions, young women taking PrEP and their social network members (female peers, male peers/partners, family, and community members) shared photographs and identified broad social-ecological causes of PrEP interruptions, including: (1) widespread misinformation about PrEP, (2) social pressures from religious communities, (3) health care staff recommendations to interrupt PrEP use, (4) partner rejection of PrEP, (5) changes in women's risk awareness, and (6) a personal desire to occasionally pause daily use. Collectively, participants identified strategies to address these challenges. These findings can inform future programs targeting the broader social-ecological influences on young women's persistent use of PrEP.
Remembering the “Dade Massacre”
Authors: Murphree Daniel S.
Published: May 2023

Just over a hundred years ago, the state of Florida created Dade Memorial Park to commemorate 108 US soldiers killed by Seminole Indians in 1835, an engagement at the time labeled “Dade’s Massacre.” Whereas the event itself briefly gained much attention throughout the United States and triggered the Second Seminole War (1835–42), the site’s creation and interpretations tell us much about the factors that shaped historical memorialization in public spaces in Florida and the Deep South. Specifically, this article examines the role of settler colonialism theory and Native American perspectives in the setting’s evolution into today’s Dade Battlefield Historic State Park.
lncRNA DIRC3 regulates invasiveness and insulin-like growth factor signaling in thyroid cancer cells
Authors: Wysocki Piotr T , Czubak Karol , Marusiak Anna A , Kolanowska Monika , Nowis Dominika
Published: May 2023

Differentiated thyroid cancers (DTCs) are malignancies that demonstrate strong but largely uncharacterized heritability. Germline variants that influence the risk of DTCs localize in disrupted in renal carcinoma 3 (DIRC3), a poorly described long non-coding RNA gene. Here, we investigated the function of DIRC3 in DTCs. Using patient-matched thyroid tissue pairs and The Cancer Genome Atlas data, we established that DIRC3 is downregulated in DTCs, whereas high expression of DIRC3 in tumors may reduce the risk of cancer recurrence. DIRC3 transcripts were enriched in cell nuclei, where they upregulated insulin-like growth factor binding protein 5 (IGFBP5), a gene that modulates the cellular response to insulin-like growth factor 1 (IGF1). Silencing DIRC3 in thyroid cancer cell lines (MDA-T32 and MDA-T120) had a dichotomous phenotypic influence: augmented cell migration and invasiveness, reduced apoptosis, but abrogated the MTT reduction rate. Transcriptomic profiling and gene rescue experiments indicated the functional redundancy in the activities of DIRC3 and IGFBP5. Moreover, the reduced level of DIRC3 enhanced the susceptibility of thyroid cancer cells to IGF1 stimulation and promoted Akt signaling via downregulation of the IGFBP5 protein. In conclusion, DIRC3 expression alters the phenotype of thyroid cancer cells and regulates the activity of the IGFBP5/IGF1/Akt axis. Our findings suggest that an interplay between DIRC3 and IGF signaling may play a role in promoting thyroid carcinogenesis.
Suberin as a bio-based flame-retardant?
Authors: Trovagunta Ramakrishna , Hubbe Martin A.
Published: May 2023

Fire hazard is a constant risk in everyday life with the use of combustibles such as polymeric materials, wood, and fabrics, to name a few. Halogenated compounds have been widely used as efficient flame-retardants, often being applied as coatings or impregnations. With growing environmental concerns and regional bans on the use of halogenated flame-retardant compounds, bio-based alternatives are garnering significant research interest. Naturally occurring materials such as eggshells, DNA, and certain proteins have developed a self-defense mechanism against fire over millions of years of evolution. Cork, a naturally occurring biological tissue in outer bark, is of interest as it is often used as a heat shield and moisture repellent, specifically in spacecraft. A deeper look into the chemical structure of cork indicates the presence of suberin, a bio-polyester group that makes up as much as 40% of its chemical composition. These bio-polyester groups play a key role as a protective barrier between the plant and the surrounding external environment. Thus, the role of suberin in plants could be mimicked for the design of biobased flame-retardant materials.
Cardiac Cancers: Classification, Diagnostics and Treatment
Authors: Simonavičius Paulius
Published: May 2023

Although rare, cardiac tumors are a type of surgical pathology that can present itself during clinical practice. Like the majority of neoplasms, these tumors are classified into two groups: primary and secondary or benign and malignant. However, the classification does not determine treatment, but the diagnostic pathway is the same and this pathology does not revolve only around the cardiologist an/or cardiac surgeon for optimal patient outcomes. That is why it is important for doctors of multiple specialties to work on cardiac tumor diagnostics and treatment all together. Aim of this study – to analyze the information about cardiac tumor classification, diagnostics, and treatment. Results of the study. The results clearly show that cardiac tumors are a rare type of pathology and their classification depends on type of tissue the neoplasm originated from. It can either be from one of heart layers (primary tumor) or a metastasis (secondary tumor). It is also important to classify these tumors into benign and malignant because treatment differs drastically. Diagnostic tests that are essential for cardiac tumors are instrumental (heart ultrasound, MRA, CTA) and blood tests (troponins, D-dimers). Treatment varies depending on tumor type however surgery is usually the only option. Treatment of malignant tumors is more complex, involving chemotherapy and/or radiotherapy and outcomes of these neoplasms are generally worse compared to treatment of benign heart tumors.
Pancreatic Mucinous Cystic Neoplasm with Associated Invasive Carcinoma: A Case Report and Literature Review
Authors: Marcinkeviciute Kristina , Jurkeviciute Digne , Stulpinas Rokas , Stratilatovas Eugenijus , Dulskas Audrius
Published: May 2023

Background. Pancreatic mucinous cystic neoplasm (PMCN) with associated invasive carcinoma is a rare entity. According to the World Health Organisation (WHO) 2010, PMCN with associated invasive carcinoma is referred to the malignant lesions of the pancreatic epithelial tumour. Case report. A 52-year-old female patient presented with pain in the umbilical and epigastric regions for 5 months and noticed a solid visible tumour on the left side of the abdomen 3 months ago when she lied down. The level of the CA125 was 47.64 U/ml (normal value <35 U/ml). Abdominal and pelvic magnetic resonance imaging (MRI) showed a cystic multiseptal mass in the left iliac region, defined as a left ovary tumour, while Computed tomography scan revealed a cystic tumour of the pancreatic tail. The patient underwent a resection of the pancreatic tail with a 20 cm cystic solid tumour, splenectomy and left hemicolectomy. Histopathology report confirmed mucinous cystic neoplasm of the pancreatic tail with associated invasive carcinoma (combined badly differentiated (G3) ductal (40%) and undifferentiated (G4) anaplastic (60%) carcinoma) pT1bN0. Postoperative course complicated with wound infection. The patient was discharged on postoperative day 10. The patient is still alive 2 years on follow-up. Conclusions. PMCN with associated invasive carcinomas are rare lesions of pancreas with relatively benign course. This malignant pancreatic tumour displays morphologies as pleomorphic epithelial cells and relatively mononuclear spindle cells, and not always tends to have underlying ovarian type stroma. The comprehensive histopathological examination of the tumour is necessary in order to cure most MCN patients with minimally invasive types.
Development and Proposal of an Institutional Safety Program in the Operation of Laser Systems
Authors: Resende Vagner , Cunha Alex , Junior Arandi Ginane Bezerra , Malthez Anna Luiza Metidieri Cruz
Published: May 2023

Laser radiation can cause undesirable biological effects on living beings; although it is not ionizing, this type of radiation can cause burns to the skin and cornea, even cataracts, depending on the wavelength and intensity of the laser radiation. Due to the wide growth of laser applications in several areas, such as research and development, services, and industry, the occupational risks concerning this non-ionizing radiation have increased considerably worldwide. Several countries have normative documents and regulatory bodies or agencies that approach occupational safety and quality regarding laser application, equipment, and machines. In Brazil, there is a lacking of laser safety documents published by a national regulatory council. Therefore, large technological centers and educational institutions, such as SENAI Institute for Innovation in Laser Manufacturing and Processing Systems (ISI-Joinville) and the Federal Technological University of Paraná (UTFPR), do not have an institutional safety program for laser operations, and to adapt to the most modern international recommendations they look for international documents and models from other institutions. The main objective of this work was to develop and propose an institutional program following Brazilian regulatory documents from the Ministry of Labor and Social Security and the most modern international standard about laser safety from the American National Standards Institute (ANSI-Z 136-1: 2014). The developed safety program was applied to ISI-Joinville, but a model was adapted to be implemented at any research center and university.