bluuebunny/crossref_metadata_2025 huggingface dataset:
Moda fantástica
Authors: Orta Matías
Published: October 2019

Nadie duda de la importancia del vestuario en el cine; innumerables prendascontribuyen a conformar la identidad de personajes, ya sean héroes o villanos, inspiradosen personas reales o productos de la mente de los guionistas. En algunos casos, hasta sonmás recordados que los otros elementos del film. El vestuario en un film hace referenciaa su status social, a su psicología y a sus deseos. En el cine fantástico, el desafío de losvestuaristas es aún mayor. La imaginación de los realizadores es puesta a prueba más queen otra clase de producciones, ya que el trabajo consiste en plasmar accesorios inventadosdesde cero, a veces vestidos por personajes no humanos, durante diferentes períodos históricos o en galaxias muy lejanas. Este trabajo estará centrado en el vestuario de películasde fantasía, ciencia-ficción y terror. El foco estará puesto especialmente en los exponentesmás representativos de cada subgénero, desde los clásicos hasta los más recientes, pero quefuncionan como los mejores modelos de tendencias que luego inspiraron a otras películas.De esta manera, podremos ver vestuarios más sobrecargados, otros más simples, perotodos inolvidables y muy influyentes en otros films y en la cultura popular
La seducción del cuerpo vestido en La fuente de las mujeres
Authors: Acar Lucía
Published: October 2019

Estamos acostumbrados a pensar en la seducción del cuerpo femenino desdela desnudez. La poca o ninguna ropa es una recurrencia en la construcción de la imagende la mujer seductora. Las tiras del vestido crean una relación frenética entre la piel y latela representando los deseos, intenciones y sentimientos, contribuyendo a la concepcionplástica de una película. Los cuerpos femeninos en La fuente de las mujeres, una películade cineasta rumano Radu Mihaileanu, son vestidos y no quieren dejarse seducir por ladesnudez, sino en virtud de una huelga de sexo, lo que provoca una revolución en unpequeño pueblo de comunidad machista y ultra conservadora.
Prólogo Universidad de Palermo
Authors: Doria Patricia M.
Published: October 2019

Esta publicación se propone ofrecer al lector puntos de reflexión sobre la temática del cuerpo y su construcción a través del Arte y el Diseño, es decir que permita observarlo más allá de su función como soporte corporal, (músculos, huesos, estructura), o como representación del imaginario social y cultural.El punto de partida de esta compilación de autores aborda el cuerpo desde diferentes puntos de vista. Se propone dar respuestas a por qué y de qué forma la representación del cuerpo ha constituido un elemento clave, para la decodificación y creación de los signos de la revalorización corporal, desde la sensibilidad, la acción y la temporalidad. Los autores traducen desde múltiples miradas la grandeza del cuerpo y expresan su creatividad en un entramado de nuevas presencias corporales.
El arte de diseñar nuestro cuerpo
Authors: Puppo Cecilia
Published: October 2019

El abordaje sobre el cuerpo desde una mirada psicoanalítica nos remonta a la constitución del sujeto humano planteando la compleja trama de relación entre los cuerpos biológico, psíquico y cultural. El ficticio yo, da entidad y estructura y descentra con sus imágenes especulares engañosas. En el inicio mismo de la formación del sujeto hay drama, sumado a las exigencias que dicta la cultura; el sujeto vive alienado, preso en su propio cuerpo. El discurso moderno produce e incita a la fragmentación, marginación y destrucción de las diferencias. En este artículo se cuestiona dicho discurso y se propone como salida el concepto de bella subjetividad.
Partir y volver. Cuba, tierra natal de Wifredo Lam y Ana Mendieta
Authors: Bonnet Eric
Published: October 2019

Tomando como punto de partida la palabra Heimat se analizan los procesos deida-vuelta. A partir de la vivencia de este acontecimiento se analizan los derroteros de loscreadores Wifredo Lam y Ana Mendieta.
La experiencia migratoria como posibilidad de creación
Authors: Erbetta Alejandro
Published: October 2019

En este ensayo se interrroga sobre cómo la actividad estética, en especial, lafotográfica rinde cuenta de las migraciones y de los procesos de mundialización humanaa tavés de los distintos modos que cada autor elige para entablar su discurso visual.
Fronteras blandas. Posibilidades de representación del horror
Authors: Labraga Denise
Published: October 2019

De cara a la diversidad de imágenes producidas a partir de la posdictadura argentina, la propuesta es tomar aquellos trabajos en los que el deseo del fotógrafo reblandece las fronteras de la representación, persiguiendo la construcción de fotografías “imposibles”
La imagen síntoma: construcciones estéticas del yo
Authors: Niedermaier Alejandra
Published: October 2019

En este escrito se intenta dar cuenta de la intensa imbricación entre la biografía de cuatro fotógrafas que atravesaron momentos histórico-culturales similares y las características estéticas que manifiestan en su obra. La etapa de formación de cada una está marcada por las diferentes vanguardias y todas han vivenciado los avatares del fenómeno emigración / inmigración. Luego y a lo largo de sus trayectorias –en diferentes países deIberoamérica– sus prácticas artísticas resultaron introductorias en los países elegidos denuevos modos de fotografiar.
Las transformaciones diagramáticas: imágenes y fronteras efímeras
Authors: Viana Joaquim
Published: October 2019

Se releva cómo la presión migratoria contemporánea provoca cambios radicales en la gestión de los flujos transfronterizos. La fotografía explora las rutas recorridas porlos inmigrantes clandestinos en sus diferentes estados de excepción.
Jorge Prelorán: las voces que aún podemos escuchar
Authors: Acosta Lucía
Published: October 2019

En la poética del cineasta argentino Jorge Prelorán las motivaciones éticas y estéticas están estrechamente vinculadas. El presente artículo ubica su filmografía en el contexto del documental etnográfico, para destacar sus rupturas y continuidades respecto a otros realizadores nacionales e internacionales. A su vez, la circulación de la obra del director permite descubrir el potencial semántico que le confiere vigencia en la actualidad.

Por último, la dimensión ética y comprometida del trabajo fílmico de Prelorán se pone de manifiesto al señalar puntos de contacto entre sus etno biografías y los conceptos de: sujeto político, subjetivación, identificación y desidentificación de Jacques Rancière.
ORAL CAVITY MICROBIOCENOSIS ASSESSMENT ON THE BASIS OF BACTERIAL ENDOTOXIN AND PLASMALOGENS IN A SALIVA BY METHOD GAS-LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY
Authors: Samoylova M. V. , Kosyreva T. F. , Anurova A. E. , Abramovich R. A. , Mironov A. Yu. , Zhilenkova O. G. , Zatevalov A. M. , Voropayeva E. A.
Published: October 2019

The concentration of plasmalogen bacterial and endotoxin levels in the saliva of patients with different severity of periodontal disease, injury prosthetic bed and with various degrees of the oral cavity microbiocenosis violations was studied. Determination of the presence of the pathological process was carried out clinically, according to the condition of periodontal tissues. The degree of microbiological disorders was assessed by the quantitative ratio of the types of microorganisms isolated from the smear taken from the gingival groove. It was found that the concentration of plasmalogen for normal microbiocenosis is not less than 0.7 µg/g. For the intermediate type of microbiocenosis, the concentration of 1.82 µg/g was determined; for dysbiosis - 5.64 µg/g, and for the expressed violation of the microbial composition accompanied by inflammatory processes - 6.54 µg/g. An increase in the concentration of bacterial endotoxin (be) more than 6.25 nanomole/g indicates the pronounced inflammatory process, regardless of the determined intensity of contamination of opportunistic gram-negative microflora.
DISTINCTIONS OF THE RESULTS OF AUTOMATED ANALYSIS AND MICROSCOPIC BLOOD INVESTIGATION (EXAMPLES OF CLINICAL CASES)
Authors: Diakonov D. A. , Rosin V. A. , Fedorovskaya N. S.
Published: October 2019

There are cases of discrepancies between the results of a microscopic examination of blood cells by morphological physicians with data obtained using an automatic analyzer in patients with a hematologic profile. It is shown that in some cases the analyzer does not determine changes in the morphology of erythrocytes, allows errors in calculating the leukoformula, differentiation of cells according to the degree of maturity, and evaluation of the number of platelets. The complementary importance of methods of light microscopy and automated blood analysis in patients with suspected pathology of the blood system is underlined.
Theoretical and methodological bases of children’s creative activity development
Authors: Dmitrieva Aleksandra
Published: October 2019

We present main approaches of foreign and domestic scientists to a problem of children’s creative activity development in contemporary conditions. We analyze several definitions of “creative activity”. We substantiate the relevance of creative activity development support of younger generation based on the analysis of regulating documents in education and culture, as well as theoretical sources on a research problem. We define prerequisites and functions of creative ac-tivity. We give the definition example of “creative activity” in terms of the psychological condi-tions defining personal development of child as an indicator of successful assignment of cultural and leisure experience. Creative activity appears in inclusion of children in the creative, originative activities aimed at implementation of potential of the personality, its self-development. Creative activity extends to productive processes necessary for the quickest way out of problematic situa-tions that arise in the management environment, education and politics sectors, cultural field, in the implementation of innovation activities, as well as in the case of new forms of creative interaction practical implementation. This phenomenon is due to the enormous potential of creative activity in such social relations as “person – person”, “person – society”, “person – nature”, “person – sign systems”, “person – technology”, “person – artistic image”.
A.S. Shishkov on Peter the Great
Authors: Dzhabbarov Ruslan
Published: October 2019

Over the last years, studying of conservative ideology became an essential part of historical researches. In this regard, the objective of research is the analysis of Peter the Great’s character made by A.S. Shishkov. To achieve this objective, we investigate the focus and reasons of changes in evolution of linguistic views regarding the reformer. We primarily use the problematic-chronological method; historical facts are studied based on principles of historicism and objectivi-ty. Peter I is presented as a positive character mainly in legends and tales of yore, which indicates Shishkov’s superficial knowledge of the reformer’s reign history. The admiral shows more favor to Peter I in public media. We assert that he admired Peter’s I moral qualities. A.S. Shishkov used Peter’s I name in political argumentation in flattering expressions. Admiring the tsar’s reformation methods and his administrative reforms, A.S. Shishkov often viewed him as a historical role mod-el. In addition to this, we prove that A.S. Shishkov criticized the Europeanization performed by Peter I encouraging to fight against it using Peter’s I methods. It is shown that A.S. Shishkov indi-cated the depletion of linguistic sphere. He argued against Peter’s I projects on the issue of serf-dom law. Philologist accused Peter I of customs and traditions violation, propagation of foreign-born enlightenment, and moral capitulation under the western influence. We identify that, accord-ing to A.S. Shishkov, Peter I adopted foreign customs in prejudice of Russian identity. The con-clusion is drawn that A.S. Shishkov saw both positive and negative sides in the personality and re-forms of Peter I.
Patrimonial archives of the Tambov landowners’ estates: the documentary heritage nationalization
Authors: Zhitin Ruslan
Published: October 2019

We consider the potential of the Russian landowners’ estates patrimonial records management as a historical source for the features characteristic of the landlord economy development after the serfdom abolition. We study the fate of patrimonial archives of Russia in the comparative aspect with the history of other countries, mechanisms of values nationalization from the largest Tambov estates, its consequences for documentary collections. An important element of the work was the consideration of historiographical aspects of the work with the private estates document circulation. Consideration of the positions of A.M. Anfimov, L.P. Kovalenko, L.P. Minarik re-garding authentic qualities of patrimonial records management allows to identify the advantages and disadvantages of using patrimonial documents in historical research. Specific characteristics of landlords’ records management are considered on the material of a separate Fund of the Novo-Pokrovsky estate in the Tambov Governorate (State archive of the Tambov Region). The Fund combines 1309 units, reflecting the history of the estate from the time of its purchase in 1895 until the liquidation of the estate in 1918. A variety of records management documentation shows the development and complexity of administrative control of a certain manor. The structure of the archive includes orders, circulars and instructions of the Main office to the manager, administrative orders of the chief manager to the heads of individual districts, cases of purchase by count A.V. Orlov-Davydov of other estates in the Tambov Governorate, books of summary budgets of savings, annual reports, abstracts of incoming papers, summary production statistics on individual holdings, credit data. These materials are reliable sources for studying the economic consequences of modernization of large landlords’ economy.
“Are you defective or immoral?”. Problems of selection and socialization of “morally defective” children in the 20s of the 20th century in Soviet Russia: regional aspects
Authors: Shcherbinin Pavel , Shikunova Inna
Published: October 2019

We consider the regional features of the social protection system of “morally handicapped” children in Tambov province in the first decade of Soviet government (1918–1928). We representatively and comprehensively investigate various poorly studied aspects of the declared scientific problem on the basis of attraction and processing of a wide complex of primary archival sources and other materials. We reveal typical regional features of the social education system formation in relation to homeless children and children with criminal tendencies in the formation period of the new socialist state at the provincial and county levels, different from the capital’s projects and instructions. We also show spontaneity and haste in the search for different forms and methods of organization of care for such socially neglected children. We clarify the main educational practices and organizational measures for the opportunities and needs of provincial institutions of the social education. We identify the main ways and methods of work with juvenile offenders during the period under review. Conclusions are drawn about the results and features of support for such “special” children and adolescents at the level of the province and county, which allowed to reconstruct the system of social protection of post-revolutionary Russia. Special atten-tion was paid to the social protection of women’s councils female workers’ children and other re-gional public organizations. Attention is paid to the importance of taking into account regional specifics and specific historical, socio-political, socio-cultural and ethno-confessional features of the social education system. We clarify the factors that had the strongest impact on the personnel, financing of children’s social institutions, as well as trends in their development in the Soviet era. We reveal the catastrophic impact of the new economic policy on the regional system of social education and the work of orphanages, where homeless children gathered, who lacked other opportunities for socialization and survival.
Content of teaching students of linguistic university grammar on the basis of Internet projects
Authors: Yuzbasheva Elina
Published: October 2019

Content of teaching foreign languages undergoes inevitable changes in connection with introduction of information and communication technologies. Education as an integral part of life of society has to match the criteria providing high-quality teaching process, at the same time the project method allows to execute the social order of society in more practice oriented approach to teaching. The place of grammar studying in the course of teaching foreign languages was not al-ways unambiguous: there were cases when it was under or overestimated in educational process. However, it is worth mentioning that without well formed grammatical skills of foreign language communication any of the most modern information and communication technologies are not capable to yield qualitative result. We consider a problem of adequate use of Internet projects for university students’ grammatical skills formation as well as an issue of the corresponding content of teaching grammar. Teaching foreign language to students of both linguistic university and other higher educational institutes is directed to formation of all components of foreign language com-municative competence. Project activity, as well as based on it educational Internet projects allow to bring this process of teaching to higher qualitative level. We carry out and develop: a) the analysis of the scientific works devoted to the concept “grammar” and its role in the history; b) the analysis of the researches devoted to selection of subject contents for grammatical skills formation of the students’ speech; c) the author’s subject contents of teaching grammar students of linguistic universities on the basis of implementation of foreign language Internet projects.
Training macrocycle development for the student handball team
Authors: Nguyen Huu Trung , Gillard Marina
Published: October 2019

The relevance of the study is due to the need to effectively develop the preparation of student sports teams in team sports. Team sports require a special approach to year-round training development, since within the framework of a single training process, it is necessary to solve prob-lems of individual, group and team sports improvement. The different level of initial preparedness of student-athletes dictates the need to create a monitoring system of preparedness level and the current state of each student who combine handball with intense educational activities. Due to the high level of academic workload, high physical and mental stress in the session period, students have little time left for training activities. At the same time, even in the absence of significant dif-ferences with the competitive activities of professional sports teams, the training of student-athletes has similar common features in the structure and content of the training process. There-fore, the purpose of our study is to identify the optimal training structure and content of student handball team. We analyze the development features of a macrocycle for preparing a student handball team for competitions. We pay attention to the main content and structure of each of the year-round macrocycle periods. General and partial volume indicators and intensity dynamics of training loads are presented and substantiated. We suggest a scheme for the use of means of restoring and improving the athletic performance of student handball players. We provide an option for the most effective training loads distribution in the year-round training cycle of the student male handball team.
Law-making in modern Russia: the problem of leveling anti-cultural manifestations (in the context of the sustainable development strategy of national state
and legal life)
Authors: Samorodov Vladimir Yuryevich
Published: October 2019

We present the study of the general scientific phenomenon of anticulture as a slice of social life and its reflection in the context of legal matter. The study of anticultural manifestations in the subject plane of modern Russian law-making, which are negative legal trends that affect the national legal life of society. We consider anticultural manifestations in law-making as the antithesis of the law-making culture, while attention is drawn to the dichotomy of the concepts of law-making culture and anticulture. Anticultural beginning in lawmaking is characterized as a negative trend of modern law-making. We outline the actual problem of these negative phenomena minimization (leveling), which in general can affect the quality and effectiveness of law-making. We carry out the analysis of law-making culture categories interrelation and anticulture by means of disclosure of essential characteristics of these concepts. The aim is to identify anticultural manifestations in law-making and develop measures to combat them. We apply methods of analysis, comparison, synthesis, modeling, and system research; also we present and characterize a number of anti-cultural manifestations in modern Russian law-making. In conclusion, we note that anticultural manifestations in law-making create prerequisites for the strengthening of negative phenomena in the national legal life that can affect its sustainable development, and therefore it is necessary to purposefully solve the problem of improving the culture of modern Russian law-making.
Legal support: universal level systematization experience
Authors: Ivanov Sergey Aleksandrovich
Published: October 2019

We present the results of a legal study which devote to the identification of provisions regulating legal assistance in the international law norms. Based on the variability associated with some political and legal trends, we identify and characterize three groups of international treaties on legal assistance, to which the Russian Federation is a party (multidimensional, sectoral and special-military). It is emphasized that, in addition to the designated classification, it is necessary to point to international agreements on legal assistance, divided depending on the subject of their conclusion: between sovereign states; between sovereign states law enforcement agencies; between other authorities of sovereign states. We reveal the international treaties specialization tendency on legal assistance in relation to situationally relevant international relations, which form the basis of the subject of regulation. The conclusion is made about a certain typicity of international acts on legal assistance, based on their construction of the content and compositional aspect. We come to the conclusion that the category “assistance” is very popular at the international level, which confirms the relevance of the stated research topic. Moreover, at the international level, the key subject of regulation is legal assistance and its subspecies differentiation is carried out in the future.
Legal nature, content and social services standard significance
Authors: Zelepukin Roman Valerevich
Published: October 2019

We raise the topic of the social services current system, the place and importance of nonprofit organizations in it. It is noted that the tendency of social services nonprofit sector transfer to the population with the subsequent reimbursement of expenses from the budget. We analyze various barriers of nonprofit organizations participation in the social services provision in the context of which it is proposed to provide an advance mechanism for reimbursement of nonprofit organizations for the social services provision. The importance of the social services standard is emphasized, its content is revealed and an attempt is made to reveal the legal nature of the standard of social services. We note the content of the standard established by the federal legislation; also we draw attention to the fact that the procedure approval for the social services provision by social service providers is attributed to the powers of public authorities of the subjects of the Russian Federation. We present the analysis of the social services provision standard in the Tambov Region by forms of social services approved by the order of Social Protection and Family Policy Department of the Tambov Region dated April 1, 2016 no. 463-ф. The points requiring adjustment from the point of view of legal technique are revealed, and also other offers on modification of the specified regulatory legal act are specified. As a result, we conclude that the social services standard, firstly, expresses the amount of social assistance guaranteed by the state, secondly, it is an exhaustive set of requirements for the service itself, allowing to plan activities and resources, and, thirdly, it is a set of requirements for quality control of social services and protection of the rights and legitimate interests of their recipients.
State coercion and its implementation in administrative proceedings
Authors: Akimova Tatyana Ivanovna
Published: October 2019

We investigate the state coercion legal nature, the implementation problems of the latter in administrative proceedings. We illustrate the positions of legal scholars regarding the views on the actual basis of the use of state coercion measures. It is emphasized that the recognition of an offense as the only factual basis for the application of state coercion measures will be valid only in the case of the application of legal liability measures, while prevention and protection measures assume the presence of other legal facts. We analyze the issues of state coercion in the light of their normative consolidation in the Code of administrative procedure of the Russian Federation. Also we investigate characteristic features of coercion in administrative proceedings. We point out on the coercion specificity in the sphere of administrative proceedings as a form of law enforcement activity, the implementation of which is entrusted to the judiciary. The problem of more precise systematization of state coercion measures in administrative proceedings is raised. We consider the actual basis issues for the coercive measures use from different positions. The necessity of studying the measures of legal coercion is determined. In addition, it is indicated that the implementation of administrative procedural coercion measures in administrative proceedings is aimed primarily at restoring the violated procedural order and is restorative in nature.
Prospects for the development of professional representation in Russian arbitration proceedings
Authors: Glukhova Oksana Yuryevna , Nazarov Valentin Vasilyevich
Published: October 2019

We investigate the development problem of professional representation in the arbitration proceedings of the Russian Federation. We believe that the professional representatives participation in the arbitration process has a very positive impact on the efficiency and quality of proceedings which is carrying out by the arbitration courts. It is stated that the need for professional representatives is primarily due to the special (economic) nature of disputes considered by arbitration courts, the participation in which persons who do not have the appropriate education and knowledge, on the one hand, as a rule, does not contribute to the effective protection of their rights, on the other – delays the consideration of cases. Thus, the Arbitration procedure code of the Russian Federation will be amended in autumn 2019, concerning the requirement of compulsory higher legal education for representatives of the parties in civil and arbitration cases. The amendments provide that in addition to lawyers, they can only be persons with a higher legal education or a degree in law. The exception is cases subject to consideration by magistrates or district courts. It is concluded that the presence of higher legal education in the near future becomes a mandatory requirement for representatives in disputes considered by the arbitration courts of the Russian Federation.
Retos del etiquetado frontal de alimentos para lograr la reducción del consumo de sodio (sal)
Authors: Vargas-Meza Jorge , Pedroza-Tobías Andrea , Campos-Nonato Ismael , Nilson Eduardo , Jauregui Alejandra , Barquera Simón
Published: October 2019

[No disponible]
Development and validation of a prediction model for six-month societal costs in older community care-recipients in multiple countries; the IBenC study
Authors: Lier Lisanne van , Bosmans Judith E , Roest Henriette G van der , Heymans Martyn W , Garms-Homolová Vjenka , Declercq Anja , Jónsson Pálmi V , Hout Hein P.J. van
Published: October 2019

Objectives To develop and validate a prediction model of societal costs during a period of six-month in older community care-recipients across multiple European countries. Methods Data from the IBenC study were used. Participants were older community care-recipients from five European countries. The outcome measure was mean six-months total societal costs of resource utilisation (healthcare and informal care). Potential predictors were assessed at baseline and included sociodemographic characteristics, functional limitations, clinical conditions, and diseases/disorders. The model was developed by performing Linear Mixed Models with a random intercept for the effect of country and validated by an internal-external validation procedure. Calibration curves and expected-to-observed (E/O) ratios were calculated. Results Living alone, caregiver distress, ADL and iADL impairment, required level of care support, health instability, presence of pain, behavioural problems, urinary incontinence, and multimorbidity significantly predicted societal costs during six months. The model explained 32% of the variation within societal costs and showed good calibration in Iceland, Finland and Germany. Minor model adaptations improved model performance in The Netherland and Italy. Conclusion The results can provide a valuable orientation for policymakers to better understand cost development among older community care-recipients. Of the predictors that were identified, caregiver distress, ADL and IADL impairment, health instability, presence of pain, behavioural problems, and urinary incontinence may be modifiable to some extent and could be targeted by interventions with the aim to reduce costs. The other, non-modifiable predictors, including living alone, required level of care support, and multimorbidity may be used by policy makers for optimal resource allocation.
Comparing intraoperative transesophageal and postoperative transthoracic echocardiography findings in mitral valve surgery: what changes?
Authors: Alves Patrícia Marques , Branco Carlos , Marinho Ana Vera , Ramalho Ana Rita Rita , Maldonado Maria João João , Coutinho Gonçalo , Prieto David , Gonçalves Lino , Antunes Pedro
Published: October 2019

OBJECTIVES Intraoperative transesophageal echocardiography (iTEE) has an important role in diagnosing the results of mitral valve (MV) replacement and repair. However, intraoperative Doppler features may be dissimilar from those measured at the postoperative follow-up period due to hemodynamic variations. There are no studies regarding MV surgery and comparisons between iTTE and postoperative transthoracic echocardiography (post-TTE). We aimed to evaluate the Doppler flow profiles observed in iTEE after MV replacement and repair and compare them with those observed in post-TTE.METHODS We conducted an observational study of 76 patients who underwent MV surgery (replacement or repair) over a 10-month period. iTEE was performed with Doppler evaluation (mean pressure gradient [MPG] and functional area). Patients were re-evaluated with TTE 72 hours after surgery (post-TTE). iTEE and post-TTE Doppler values were then compared and correlated.RESULTS The patients’ mean age was 59 ± 18 years and 55% were women. The prevalence of severe mitral regurgitation and severe mitral stenosis was 77.6% and 22.4%, respectively. MV repair was performed in 71% of cases. iTEE Doppler parameters correlated with post-TTE parameters, with minimal differences, specially in the MV repair group. The postoperative MPG was +0.4 ± 1 mmHg higher in the MV repair group and +1.0 ± 1.8 mmHg in the MV replacement group. There was global improvement in terms of systolic pulmonary artery pressure, although left ventricular ejection fractions were slightly reduced during the postoperative evaluation.CONCLUSIONS Our study demonstrates the usefulness of iTEE and its importance in establishing possible reference values for postoperative follow-ups.
Identification for prognostic value of differentially expressed genes in immune microenvironment of clear cell renal cell carcinoma
Authors: Zhang Xingming , Yin Xiaoxue , Liu Zhenhua , Sun Guangxi , Zhu Xudong , Zhang Haoran , Zhu Sha , Zhao Jinge , Chen Junru , Chen Ni , Shen Pengfei , Wang Jia , Zeng Hao
Published: October 2019

Background: Genes related to Anchorimmune microenvironment of clear cell renal cell carcinoma (ccRCC) remains unclear. We aimed to identify related to immune microenvironment and to screen the most significant genes to predict outcomes of ccRCC. Methods: Gene expression and clinicopathological data from TCGA data portal were obtained (KIRC). Immune and stromal scores were calculated based on ESTIMATE algorithm. DEGs between low and high groups of immune scores were identified. Subsequent functional enrichment analysis and protein-protein interaction of DEGs were conducted by DAVID database. Results: Patients were divided into low and high groups by medians according to immune (median: 1038.45) and stromal scores (median: 667.945), respectively. Immune scores were significantly correlated with clinicopathological parameters and overall survival (OS). Based on immune scores, 1433 genes were up-regulated, and among them, 890 DEGs were significantly associated with OS. Based on top 10 DEGs, cases with number of up-regulated genes ≥5 were associated poor OS (P = 0.002). In addition, the mean differences of percentages of CD8 T cells (11.32%), CD4 memory resting T cells (-4.52%) and mast resting cells (-3.55%) between low and high immune scores were the most significant. Conclusions: A list of immune microenvironment-related genes in ccRCC was initially identified, and high immune score was an independent poor prognostic factor of OS. Furthermore, the combination of these genes might use to predict the efficacy of immunotherapy. Further analyses of these genes were warrant to explore their potential association with the prognosis of ccRCC.
Determining Factors Affecting The Medical Interns’ Choice Of Specialties Among Governmental Universities In Riyadh
Authors: Swaidan Ahmad Tariq Al , Luhidan Lama Abdullah Al , Albarrak Khaled Abdullah , Mubrick Rehab Abdullah Al , Suwaidan Hessah Ibrahim Al , Alshammari Rawan Abdulaziz , Barakeh Rima MHD Belal , Al-Ghusoon Moath Khalid , Alruwaily Bander Munir , alshammari sulaiman A
Published: October 2019

The nature of experience during the medical study at university may play an essential role in choosing the specialty. Objectives: to determine the effect of goveremtnal universities in general and on medical interns' career choice , taking into consideration the gender difference. Furthermore, to find out when governmental universities educate their students about the different specialties. Method: It was a cross-sectional study approved in July in 2018 that included 234 Saudi medical intern students from four different medical collages in governmental universities in Riyadh. These were King Saud University (KSU), Princess Norah University (PNU), Imam University (IU), and King Saud bin Abdulaziz for Health and Science (KSAU-HS) with consideration of gender differences and availability. All participants who are selected randomly completed an online-questioner. Result: Around two thirds (66%) of the participants ensure that their governmental universities had a positive influence in choosing the specialties dividing equally between both genders. According to the participants’ perceptions, all the items of the medical education system did not affect in choosing the specialty except three of them that have a positive effect which are elective experience (43.59%), clinical year (40.6%) and the personality of instructor (38.46%). Furthermore, one-third (33%) of the participants ensure that they are educated about the specialties in the third year. The most common positive factor is elective experience by 19.36%, while the most common negative factors are improper block duration and the personality of the instructor by 14.52%. Conclusion : Most governmental universities have a positive effect on their students' career choice, and they educate pre-graduate students about specialties.
A Novel FOXL2 Missense Mutation, c.1068G>C, In Chinese Families with Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Type II
Authors: Wang Shaoyun , He Fanglin , Jia Ruobing , Ge Shengfang , Song Xin , Jia Renbing
Published: October 2019

Background Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is a hereditary disease caused by a mutation in the forkhead box L2 ( FOXL2 ) gene. Female patients suffering from premature ovarian failure (POF) were classified as type I, and others were classified as type II. We aimed to clarify a novel FOXL2 indel mutation in Chinese families and to predict the POF risk in the affected patient.Methods Three generations of one Chinese family with BPES were enrolled in this study. Blood samples from patients of this family were collected and then analysed by whole-exome sequencing. Confocal microscopy was performed to observe the subcellular location. Transactivation studies were performed with real-time PCR.Results This novel mutation (c.1068G>C) is located in the downstream of DNA-binding forkhead(FHD) domain, and the mutant protein could also exhibit transactivation capacity of StAR , a key regulator of POF. Conclusively, we discovered a novel FOXL2 mutation and predicted that female patient in this family should be classified as type II BPES.Conclusions Our study revealed a novel missense mutation (c.1068G>C) and expanded the spectrum of FOXL2 gene mutations. Although we were not able to determine the classification from clinical manifestation, we discovered the patient developed type II BPES through subcellular distribution and transactivation analysis.
The Epidemiology Of Primary Head And Neck Cancer In Black Lion Specialized Hospital Oncology Center, Ethiopia: A Hospital Based Retrospective Study
Authors: Tefera Amare Teshome , Bekele Biruk Girma , Dejene Demerew , Workicho Abdulhalik , Tigeneh Wondemagegnhu
Published: October 2019

Background Unfortunately, despite an increase in medical knowledge, the treatment need of head and neck cancers (HNCs) have not been improved in Ethiopia. In addition, there is no published evidence in the epidemiology of head and neck cancer patients in the country. The present study aimed to describe the prevalence and pattern of HNCs among patients seen at Black Lion Hospital oncology center.
Preoperative lymphocyte to monocyte ratio and prognostic nutritional index were correlated with clinical outcomes in patients with operable colon cancer
Authors: li zhigui , Ni Tiangen , Zhou Yong , Wu Xiaoting
Published: October 2019

Background: Systemic inflammation plays an important part in tumorigenesis and progression. The predictive values of the preoperative lymphocyte to monocyte ratio (LMR) and prognostic nutritional index (PNI) in colon cancer remained unclear. Methods: A total of 308 patients with colon cancer undergoing radical resection were enrolled and analyzed. The receiver operating curves were applied to identify the thresholds for these biomarkers. Kaplan-Meier method and multivariate analysis were used to identify independent prognostic factors. Results: The univariate analysis showed that elevated LMR and PNI were significantly correlated with better overall survival and progression-free survival. The multivariate analysis showed that LMR and PNI were the independent prognostic factors for overall survival. Conclusions: Preoperative LMR and PNI could serve as useful prognostic factor in patients with colon cancer undergoing radical resection.
Factors associated with older adults' ADL in urban area of Hangzhou, China — a cross-sectional study
Authors: Rong Chao , Wang Xiao-Lan , Ye Xiao , Sun Yan-Chun , Jiang Shu-Han , Shen Shu-Han , Cao Wei-Ming , Xu Cai-Ming
Published: October 2019

Background : To explore socioeconomic associated factors of activities of daily living (ADL) among the elderly in an urban setting, and to provide evidence for designing appropriate long-term care system. Methods : Participants were selected using the method of combining stratified sampling with judgment sampling. 500 older adults were effectively surveyed. Rank sum test was used to compare the ADL of the elderly with different socio-demographic characteristics. The multiple generalized linear model and ordinal logistic regression model were conducted to analyze factors correlated with ADL. Results : Rank sum test showed that the ADL total scores of the elderly with different gender, age, marital status and living situation were statistically different ( P <0.05). The generalized linear model showed that age, self-rated health status and living situation were significantly associated with ADL total scores ( P <0.05). The ordinal logistic regression showed that gender, age, self-rated health status, the number of chronic diseases and living situation were significantly associated with ADL level ( P <0.05). Conclusion : Future interventions to improve elderly care service for urban elderly in eastern China should focus on instrumental functions, rather than on basic ADL. Further strengthen medical service functions in nursing homes. Community health service center should provide high quality health services for the elderly living in communities and homes. Build more nursing homes in China. The elderly who are not in marriage should be the focus population of long-term care.
Identification of differentially expressed microRNAs under imidacloprid exposure in Sitobion avenae Fabricius
Authors: Zhang Baizhong , Su Xu , Xie Lanfen , Dong Wen-Yang , Kong Fan-Bin , Liu Junjie , Lu Liuyang , Li Ya-She , Zhang Shouping , Shi Ming-Wang , Chen Xi-Ling , Gao Xi-Wu
Published: October 2019

Background

MicroRNAs (miRNAs), which are short single-stranded non-coding RNAs, regulate the expression of target genes, especially those involved in the regulation or metabolism of endogenous or xenobiotic compounds.Results

De novo assemblies of the transcriptome of Sitobion avenae Fabricius under control conditions and under imidacloprid treatment were obtained using Illumina short-read sequencing technology. Fifty-seven miRNAs, of which 36 were known and 21 were novel, were identified. Quantitative analysis of miRNA levels showed that five miRNAs were significantly up-regulated, and 11 miRNAs were significantly down-regulated in the nymphs of S. avenae treated with imidacloprid in comparison with those of the control. Analysis of the candidate target genes in S. avenae that could be regulated by these miRNAs were also carried out. The functions of the miRNAs, which could potentially regulate target genes that participate in metabolism, regulatory or detoxification pathways in S. avenae , were clarified based on Gene Ontology and KEGG pathway analysis. The effects of the miRNAs api-miR-1000, api-miR-316, and api-miR-iab-4 on susceptibility of S. avenae to imidacloprid was determined. Modulation of the abundances of api-miR-1000, api-miR-316, and api-miR-iab-4 by the addition of the correspondign inhibitors to the artificial diet significantly changed the susceptibility of S. avenae to imidacloprid, which further demonstrated the effect of these miRNAs on the regulation or metabolism of insecticides.Conclusion

The results of this study suggested that miRNAs differentially expressed in response to imidacloprid could play a critical regulatory role in the resistance of S. avenae to imidacloprid.
PRÁTICAS DE GOVERNANÇA CORPORATIVA NO SETOR SAÚDE
Authors: Silva Larissa Karoline Souza , Silva Antonio Rafael Holanda da , De Luca Marcia Martins Mendes , Vasconcelos Alessandra Carvalho de
Published: October 2019

Atrelada ao aperfeiçoamento dos sistemas de gestão, para agregação de valor à riqueza dos acionistas, a governança corporativa propicia um modelo decisório equilibrado, na medida em que ajuda a reduzir excessos praticados por gestores. Assim, analisam-se aqui as práticas de governança corporativa divulgadas pelas empresas do setor saúde listadas na B3 e na Nyse, bem como sua relação com o desempenho. Para tanto, reúnem-se dados de 32 companhias, referentes ao período de 2013 a 2017, coletados nos Formulários de Referência, no Annual Reporting,nosformulários 20-F e 10K, na base de dados Economática®e no Center of Research in Security Prices(CRSP). Os resultados apontam que as empresas estrangeiras listadas na Nyse apresentam melhores índices de governança corporativa se comparadas com aquelas listadas na B3, além de que foi constatado que entre os dois grupos há diferenças entre médias estatisticamente significantes para o índice de governança, considerando-se as práticas do conselho de administração. Os resultados não apresentaram significância para se inferir qualquer correlação entre o índice de governança corporativa e as medidas de desempenho empregadas.
INOVAÇÕES EM SERVIÇOS DE DOAÇÃO E TRANSPLANTE DE ÓRGÃOS: REVISÃO SISTEMÁTICA DA LITERATURA
Authors: Siqueira Marina Martins
Published: October 2019

Os processos de doação/transplante de órgãos são altamente complexos e possuem significativo potencial para melhorias advindas de inovações. Este artigo visa sintetizar a literatura sobre inovação em serviços de doação/transplante, analisando os tipos e enfoque das inovações e descrevendo lacunas e oportunidades de pesquisa. Foi realizada busca sistemática em bases de dados de gestão e saúde, aplicando descritores que integram os temas de inovação e de doação/transplante. De 115 artigos inicialmente retornados, 31 foram analisados. Os resultados indicam concentração de estudos nos Estados Unidos e que endereçam o transplante de rins e fígados a partir de doadores falecidos.  Em sua maioria, são estudos empíricos, predominantemente ensaios clínicos. De modo geral, as inovações são mensuradas a partir de seus efeitos em um grupo de indivíduos e se distribuem nas diversas etapas do processo de doação/transplante. Fica evidente que as inovações no campo são analisadas majoritariamente sob enfoque clínico, através da descrição da inovação e de seus resultados médicos para pacientes. A escassez de debates sobre a gestão do processo de inovação abre espaço para pesquisas futuras.
A Strategic Solution to Turkey’s Intermediate Goods Problem: Ceyhan Energy Specialized Industrial Zone
Authors: EKİNCİ Fırat , BİLGİLİ Mehmet
Published: October 2019

There is an on-going demand for energy from hydrocarbon compounds and intermediate goods in meeting the need for both production and intermediate products. The European Union and Turkey’s need for energy and intermediate goods are provided by petroleum and natural gas imported from geographically nearest energy regions through pipelines. In this study, a strategic solution to demand for energy in Turkey is proposed. Furthermore, information about the energy status, the chemical sector and intermediate goods imports of Turkey is provided. Considerations are proposed on the capabilities of petrochemical plants to be established in Ceyhan Energy Specialized Industrial Zone (CESIZ) as an outlet of petroleum from Azerbaijan and Iraq and a potential logistic energy base in the Eastern Mediterranean region. Ceyhan Energy Specialized Industrial Zone, as the first energy zone in Turkey and the nearby region, is introduced and the investors are briefed on the petrochemical facilities planned to be established in the zone. The importance of intermediate chemical products produced by petrochemical plants to be established in Ceyhan Energy Specialized Industrial Zone in reducing the country’s foreign trade deficit is revealed. Due to lack of studies conducted on CESIZ in the literature, this study would contribute to potential investors and academicians.