bluuebunny/crossref_metadata_2025 huggingface dataset:
E-CropReco: A Dew-Edge-based Multi-parametricCrop Recommendation Framework for Internet ofAgricultural Things
Authors: Bera Somnatha , Dey Tanushree , Mukherjee Anwesha , Buyya Rajkumar
Published: September 2022

Crop productivity prediction and recommendation is a significant research area of smart agriculture. This paper proposes an Internet of Things (IoT) framework based on dew computing, edge computing, and federated learning, where soil parameter, weather, and climate data are analysed to predict the crop productivity of a land, and then recommend suitable crop for the land. The dew layer pre-processes and accumulates the received sensor data, and forwards to the edge server. The edge server analyses the sensor data and the climate data, and then forwards the result along with the model characteristics to the cloud for further analysis. The proposed framework is simulated in iFogSim. The theoretical analysis shows that the proposed framework has reduced the delay by 60-70% approximately and power consumption by 70-80% approximately than the conventional IoT-cloud framework. We also observe that the proposed framework has reduced the delay by 12-35% approximately and power consumption by 30-50% approximately than the edge-cloud framework. We compare four machine learning algorithms based on their performance in data analysis in terms of precision, recall, accuracy, and F-Score. We observe that each classifier obtains more than 95% prediction accuracy. An Android application is also proposed for crop recommendation.
Identification of network-based differential gene expression signatures and their transcriptional factors to develop progressive blood biomarkers for Alzheimer’s disease
Authors: Jayaswamy Pavan K , Gollapalli Pavan , Alexander Lobo Manuel , M Vijaykrishnaraj , Patil Prakash , Shetty Praveenkumar
Published: September 2022

Background: Alzheimer's disease (AD) can go years without being undiagnosed due to a lack of biomarker identification with a growing incidence rate in the geriatric population. Identifying genes and their transcriptional factors and kinases that regulate the phosphorylation and pathogenesis of AD is a state-of-art approach to identifying novel diagnostic biomarkers.
Methodology: Microarray dataset GSE140829 was retrieved from the GEO database to identify differentially expressed genes (DEGs) between AD and control samples. Furthermore, a protein interaction network was built using the String database, and DEGs were examined using Cytoscape based on high betweenness centrality (BC) and degree values. Additionally, the hub genes were identified via Cytohubba, and eight modules were then identified using molecular complex detection (MCODE).
Results:
Using a Venn diagram, we mined 1674 common DEGs from AD and control samples. The primary interaction data from the STRING consists of 1198 nodes and 1992 edges, which serve an extenuated network. Further, a core network was extracted from an extended network that consists of 676 nodes connected via 1955 edges and were analyzed based on high BC and Degree values. Based on the network topological analysis and network clustering, the hub genes were identified and further validated by coparing them with the backbone network. Compelling results from both the core network and backbone network HSP90AA1identified as a major blood biomarker, followed by HSPA5, CREBBP, UBC, GRB2, MAPK3, and TRAF6 are selected as the major biomarkers.
Conclusion:
This study shows the potential for predicting AD risk factors and identifies promising blood biomarkers for early AD diagnosis. Additionally, developing inhibitors for the identified transcriptional factors and kinases might improve future therapeutic applications.
Transcriptome Analysis of the Mouse Medial Prefrontal Cortex in Chronic Constriction Injury Model: Implications of neuropathic pain-induced cognitive impairment
Authors: Zheng Qi-Min , Zhou Zi-Rui , Hou Xin-Yu , Lv Ning , Zhang Yu-Qiu , Cao Hong
Published: September 2022

Chronic pain patients often complain their decreased cognitive function. However, the comorbidity mechanism between neuropathic pain and cognitive dysfunction still remains largely unknown. Here, we examined changes in the transciptomic profiles in the medial prefrontal cortex (mPFC) of mice with chronic pain and cognitive impairment using RNA sequencing (RNA-seq) technology. A mouse model of peripheral neuropathic pain was induced via chronic constriction injury (CCI) of the sciatic nerve. CCI mice developed sustained mechanical allodynia and thermal hyperalgesia, as well as cognitive impairment four weeks after surgery. Comparing with the naïve group, RNA-seq identified a total 309 and 222 differentially expressed genes (DEGs) in ipsilateral and contralateral mPFC of CCI model mice, respectively. GO analysis indicated that the functions of these gene families are mainly enriched in immune and inflammation-related processes such as interferon-gamma production, cytokine secretion etc. KEGG analysis further showed the enriched neuroactive ligand-receptor interaction signaling pathway and Parkinson disease pathway that have been reported to be importantly involved in chronic neuralgia and cognitive dysfunction. Our study may provide insights into understanding the possible mechanisms underlying pain-related cognitive disorders.
Psychometric analysis of the Treatment Self-Regulation Questionnaire-Persian (TSRQ-P) version: autonomous regulation appraisal among the Iranian type 2 diabetes patients
Authors: Matin Habibeh , Sarbakhsh Parvin , Shaghaghi Abdolreza
Published: September 2022

Background: Autonomous self-regulation is a proxy for adapting long-term healthy behaviors with major impact on prevention of chronic illnesses. The psychometric properties of the Treatment Self-Regulation Questionnaire- Persian version (TSRQ-P) was assessed in this study for use in examination of autonomous regulation among the Iranian type 2 diabetes patients.
Methods: The preliminary draft of the TSRQ-P was prepared based on a standard translation/back translation procedure and 15 allied health specialists assessed its face and content validities. The internal consistency measure of the Cronbach’s alpha and Intraclass Correlation Coefficient (ICC) were estimated to verify the TSRQ-P’s content validity and reliability. The exploratory (EFA) and confirmatory factor (CFA) analyses were performed to check the scale’s structural components.
Results: The calculated Cronbach’s alpha= 0.893 and ICC= 0.982 deemed the scale as content valid and acceptable in terms of measurement invariance. The EFA and CFA outputs yielded two distinct factor structure for the TSRQ-P (RMSEA=0.078, NFI=0.849, RFI=0.806, IFI=0.913, TLI=0.886, CFI= 0.911).
Conclusion: The TSRQ-P indicated robust psychometric features for application among Persian-speaking type 2 diabetes patients. Due to cross-borders cultural diversity of the subgroups of Persian speaking populations, further psychometric scrutiny is recommended to prevent bias and sociolinguistic inconsistencies.
Comparison of treatment outcomes of 360° intraoperative laser retinopexy and focal laser retinopexy with pars plans vitrectomy in patients with primary rhegmatogenous retinal detachment
Authors: Zheng Ying , Schindler Philip , Druchkiv Vasyl , Schulz Jan , Spitzer Martin , Christos Skevas
Published: September 2022

Background
This study was to compare the outcomes of 360° intra-operative laser retinopexy (ILR) and focal laser retinopexy in treating patients with pars plans vitrectomy (PPV) for primary rhegmatogenous retinal detachment (RRD). To identify other potential risk factors for retinal re-detachment after primary PPV.
Methods
This was a retrospective cohort study. Three hundred and forty-four consecutive cases of primary rhegmatogenous retinal detachment treated with PPV were included between July 2013 and July 2018. Clinical characteristics and surgical outcomes were compared between focal laser retinopexy and additional 360° intra-operative laser retinopexy groups. Both univariate and multiple variable analysis were used to identify potential risk factors for retinal re-detachment.
Results
Median follow-up was 6.2 months. 17/203 eyes (8.4%) in the 360° ILR group had retinal re-detachment after primary PPV, which was significantly lower compared to the focal laser retinopexy group (19/141 eyes, 13.5%) (p < 0.05). In multivariate Cox regression, the risk factors for retinal re-detachment were without additional 360° ILR, diabetes and macula off before the primary surgery (relatively OR = 0.456, 95%-CI [0.245–0.848], p < 0.05; OR = 2.301, 95% CI [1.130–4.687], p < 0.05; OR = 2.243, 95% CI [1.212–4.149], p < 0.05).
Conclusions
Additional 360° ILR group had a significantly lower rate of retinal re-detachment when compared with focal laser retinopexy group. Our study also elucidated that diabetes and macular off before the primary surgery might also be the potential risk factors for higher rate of retinal re-detachment outcome.
Trial registration:
This was a retrospective cohort study.
Dynamic behaviours of monodisperse double emulsion formation in a tri-axial capillary device
Authors: Dai Yuchen , Cha Haotian , Nguyen Nhat-Khuong , Ouyang Lingxi , Galogahi Fariba , Yadav Ajeet Singh , An Hongjie , Zhang Jun , Ooi Chin Hong , Nguyen Nam-Trung
Published: September 2022

We investigated experimentally, analytically and numerically the formation process of double emulsion formations under dripping regime in a tri-axial co-flow capillary device. The results show that mismatches of core and shell droplets under a given flow condition can be captured both experimentally and numerically. We propose a semi-analytical model using the match ratio between the pinch-off length of the shell droplet and the product of the core growth rate and its pinch-off time. The mismatch issue can be avoided if the match ratio is lower than unity. We considered a model with the wall effect to predict the size of the matched double emulsion. The model shows slight deviations with experimental data if the Reynolds number of continuous phase is lower than 0.06, but asymptotically approaches to good agreement if the Reynolds number increases from 0.06 to 0.14. The numerical simulation generally agrees with the experiments under various flow conditions.
The spatio-temporal landscape of the transcriptome and metabolome of cotton fiber cells during their initiation and late development
Authors: Sun Xuwu , Qin Aizhi , Wang Xingxing , Ge Xiaoyang , Liu Zhixin , Guo Chenxi , Yu Xiaole , Zhang Xianliang , Lu Yao , Yang Jincheng , He Jiuming , Zhou Yaping , Hu Mengke , Liu Hao , Zhao Zihao , Hu Guanjing , Li Wei , Zang Xinshan , Dai Shuai , Sun Susu , Tong-Villalobos Lenin , Herrera-Estrella Luis , Tran Lam-Son Phan , Ma Xiongfeng
Published: September 2022

Cotton fibers develop from epidermal cells in the outer integument of ovules. The regulatory process underlying fiber cell development has been extensively studied, little is known about the spatio-temporal profiles of transcriptomes and metabolomes during its development. Here we characterized the dynamics of transcriptome and metabolome during the early developmental stages of cotton fiber cells using a combination of spatial transcriptomic, single-cell transcriptomic, and spatial metabolomic analyses. We identified the key genetic regulators and metabolites that initiate and determine the fate of fiber cells. Both knockdown and gain-of-function analyses of one new identified marker gene BEE3/Gh_A09G062900revealed its important role in the initiation of cotton fiber. We also designed a website for the public visualization of spatial gene expression in cotton that provides important reference datasets of spatio-temporal gene expression and can be used to further decipher the genetic and metabolic regulation of cotton fiber development (http://CottonOvule.cricaas.com.cn/).
Binge Eating Disorder: an Online Multidisciplinary Approach in Its Treatment
Authors: Valdez-Aguilar Mariana , Vázquez-Arévalo Rosalia , López-Aguilar Xóchitl , Martínez Ana Olivia Ruíz , Rosinska Magda , Mancilla-Díaz Juan Manuel
Published: September 2022

Background: Binge eating disorder (BED) is the most frequent loss of eating behavior among the population and the one that has received the least study in its treatment. Many studies on interventions and BED treatments have been carried out in the United States and Europe, few have been reported in Latin American populations. People with this disorder not only have physical consequences but also social and psychological ones, so a multidisciplinary treatment is a good alternative to treat this condition.
Objective: To evaluate the effectiveness of a multidisciplinary online treatment (psychological, nutritional, and physical activity) in patients with Binge Eating Disorder (BED).
Method: 15 Fifteen people diagnosed with BED (2 men and 13 women) with a mean age of 34.93 years (SD=11.91) and a mean initial BMI of 42 participated in this study. The participants were divided into two groups according to the severity of the disorder. The treatment was carried out over 28 sessions, each being two hours per week consisting of 1 hour of group therapy and 1 hour of individual therapy. There were four evaluations: pre, post and two follow-ups.
Results: Five patients did not complete the treatment (30%). The comparisons were made through the non-parametric Friedman test, finding a statistically significant decrease in binge eating symptoms (x2=15.57; p=.001), anxiety symptoms (x2=15.96; p=.001) and depression (x2=15.03; p=.002). There was an improvement in clarity (x2=11.60; p=.010) and emotional regulation (x2=7.75; p=.050), only in women. The patients reduced their body weight, andd improved their eating and exercise habits by introducing fruits and vegetables and including 20-30 minutes of physical activity into their daily routine. Regarding the Objective Clinical Change Index (OCC) From the objective clinical change, a positive change was observed in all the variables addressed.
Conclusions: The data presented allowed us to conclude that the online multidisciplinary intervention was effective in the treatment of BED.
Trial registration:Retrospectively registered
Comparison of safety and efficacy between Janus kinase inhibitors and abatacept for rheumatoid arthritis-associated interstitial lung disease
Authors: Tsujii Atsuko , Isoda Kentaro , Yoshimura Maiko , Nakabayashi Akihiko , Kim Dong-seop , Tamada Tatsuya , Yamamoto Kurumi , Ohshima Shiro
Published: September 2022

Background: Interstitial lung disease (ILD) related to Rheumatoid Arthritis (RA) is among the leading causes of death and an essential prognostic factor. There is only limited evidence for the safety of anti-rheumatic drugs for patients with RA-ILD. The aim of this study is to investigate the safety and efficacy of Janus kinase inhibitors (JAKis) by comparing it with abatacept (ABT) in patients with RA-ILD.Methods: This single center, retrospective nested case–control study enrolled patients with RA-ILD treated with JAKi or ABT. To determine the safety of the two drugs for existing ILD, we compared their drug persistency and incidence rates of pulmonary complications. For their efficacy as RA treatment, disease activity scores and prednisolone (PSL)-sparing effect were compared. We performed propensity score matching to match the groups’ patient characteristics.Results: We studied 71 patients with RA-ILD (ABT, n = 45; JAKi, n = 26). At baseline, the JAKi group had longer disease duration, longer duration of past bDMARD or JAKi use and higher usual interstitial pneumonia rate. After propensity score matching, no significant differences in patient characteristics were found between the two groups. No significant difference in the drug persistency rate for the first 2 years (ABT, 61.9%; JAKi, 42.8%;P =0.256) were observed between the two matched groups. The incidence rate of pulmonary complications did not differ significantly between the two groups (P =0.683). Regarding the efficacy for RA, a significant decrease in disease activity scores after the 1-year treatment was observed in both groups, and PSL dose was successfully tapered, although no significant differences were observed between the two drugs.Conclusions: JAKi is as safe and effective as ABT for patients with RA-ILD. JAKi can be a good treatment option for such patients.
Double-slot Ultra-compact Polarization Beam Splitter Based on Asymmetric Hybrid Plasmonic Structure
Authors: Wang Fang , Liu Hua , Ma TAO , Ma Shou Dao , Liu Yu Fang
Published: September 2022

To improve the extinction ratio of a polarization beam splitter, we propose a dual-slot ultra-compact polarization splitter (PBS) consisting of a hybrid plasma horizontal slot waveguide (HSW) and silicon nitride hybrid vertical slot waveguide (VSW). At the same time, the coating material is silicon dioxide, which can not only prevent the oxidation of the mixed plasma but also facilitate the integration with other devices. The mode characteristics of the HSW and VSW are simulated by using the finite element method (FEM). At suitable HSW and VSW widths, the TE polarization modes in HSW and VSW are phase-matched, while the TM polarization modes are phase mismatched. Therefore, the TE mode in HSW waveguide is strongly coupled with VSW waveguide by adopting a dual-slot, while the TM mode directly passes through the HSW waveguide. The results show that PBS achieves an extinction ratio (ER) of 35.1 dB and insertion loss (IL) of 0.34 dB for TE mode at 1.55 µm, For TM mode, PBS reached 40.9 dB for ER and 2.65 dB for IL. The proposed PBS is designed with 100 nm bandwidth, high ER, and low IL, which can be suitable for photonic integrated circuits (PICs).
Transaction Prices of German Closed-End Real Estate Funds in the Secondary Market and Their Influencing Factors
Authors: Aryoubi Abdullah , Bossauer Eduard
Published: September 2022

This study is the first to assess and contribute to a better understanding of the factors affecting the prices of closed-end real estate funds (CEREFs) in Germany’s secondary market. The dataset is based on 16,718 observations of realized transaction prices from 412 different German CEREFs; the factors comprise macroeconomic, fund, property, and liquidity variables. We regress macroeconomic factors on benchmark variables, such as listed real estate assets and the stock market, to observe whether German CEREFs react differently from the overall economic state from a portfolio diversification perspective. The benchmark variables are homogeneously driven by stock market excess return, DAX volatility index (VDAX) growth, and, to a certain extent, the bond rate, while CEREFs are mainly affected by the unemployment rate and economic activity. Fund and property age have a significant impact on CEREFs. Additionally, they have optimal levels at which their respective impacts start to reverse. Initial fund leverage and rising liquidity in the secondary market also have a significant impact. However, the observed effects vary across the types of real estate held by CEREFs, and investors must consider this in their pricing policies. Finally, this study presents a comprehensive overview of the German secondary market environment for CEREFs and examines their development.
Positron emission tomography imaging of the sodium iodide symporter senses real-time energy stress in vivo
Authors: Dzien Piotr , Mackintosh Agata , Malviya Gaurav , Johnson Emma , Soloviev Dmitry , Brown Gavin , Uribe Alejandro Huerta , Nixon Colin , Lyons Scott K. , Maddocks Oliver , Blyth Karen , Lewis David Y.
Published: September 2022

Background: Tissue environment is critical in determining tumour metabolic vulnerability. However, in vivo drug testing is slow and waiting for tumour growth delay may not be the most appropriate endpoint for metabolic treatments. An in vivo method for measuring energy stress would rapidly determine tumour targeting in a physiologically relevant environment. The sodium-iodide symporter (NIS) is an imaging reporter gene whose protein product co-transports sodium and iodide, and positron emission tomography (PET) radiolabelled anions into the cell. Here, we show that PET imaging of NIS-mediated radiotracer uptake can rapidly visualise tumour energy stress within minutes following in vivo treatment.
Methods: We modified HEK293T human embryonic kidney cells and A549 lung cancer cells to express transgenic. We treated cells and implanted tumours with drugs that caused metabolic stress to determine the effects in NIS activity and energy charge. We used [18F]tetrafluoroborate positron emission tomography (PET) imaging to non-invasively image NIS activity in vivo.
Results: NIS activity was ablated by treating HEK293T cells in vitro, with the Na+/K+ ATPase inhibitor digoxin, confirming that radiotracer uptake was dependent on the sodium-potassium concentration gradient. NIS-mediated radiotracer uptake was significantly reduced (-58.2%) following disruptions to ATP re-synthesis by combined glycolysis and oxidative phosphorylation inhibition in HEK293T cells and by oxidative phosphorylation inhibition (16.6%) in A549 cells in vitro. PET signal was significantly decreased (-56.5%) within 90 minutes from the onset of treatment with IACS-010759, an oxidative phosphorylation inhibitor, in subcutaneous transgenic A549 tumours in vivo, showing that NIS could rapidly and sensitively detect energy stress non-invasively, before more widespread changes to phosphorylated AMP-activated protein kinase, phosphorylated pyruvate dehydrogenase and GLUT1 were detectable.
Conclusions: NIS acts as a rapid metabolic sensor for drugs that lead to ATP depletion. PET imaging of NIS could facilitate in vivo testing of treatments targeting energetic pathways, determine drug potency and expedite metabolic drug development.
Spatially-explicit water quality responses to freshwater discharge in a tropical estuary, Hilo Bay, Hawai‘i
Authors: Lucas Sydney N. , Fouad Geoffrey , Adolf Jason E.
Published: September 2022

Hilo Bay, Hawai’i is an estuary of great importance to its neighboring coastal community, but is threatened by impaired water quality indicated by excessive turbidity and chlorophyll a associated with river discharges of sediments and nutrients. The Wailuku River in the western half of the bay is the primary source of freshwater discharge, hypothesized here to form a surface-water dominant half of the bay with different water quality traits than the groundwater dominant, eastern half of the bay where the spring-fed Wailoa River discharges. The water quality of both halves of the bay over different flow conditions of the Wailuku River is examined in this study using spatially explicit water quality sampling which collects hundreds of samples in either half of the bay at about every 40 meters. The dense sample shows significant differences between the two halves of the bay, with greater salinity dilution and turbidity in the surface-water dominant area. Both salinity and turbidity have a predictable relation to discharge, with salinity decreasing and turbidity increasing in higher flow conditions. Chlorophyll a, however, has a more complex relation to discharge, as chlorophyll a concentrations are greatest in high-flow conditions, but this may be confounded by the different seasons of the water quality samples. Furthermore, significantly greater chlorophyll a concentrations in the groundwater dominant half of the bay in low-flow conditions shows that discharge may be spuriously correlated to chlorophyll a, and further studies of the effects of surface-water discharge on chlorophyll a concentrations are warranted.
Kearifan Lokal dalam Mitigasi Bencana Gunung Api di Padukuhan Pangukrejo Pasca Erupsi 2010
Authors: Puspita Dewi  , Winarna
Published: September 2022

Title: Local Wisdom in Volcanic Disaster Mitigation in Pangukrejo Village Post 2010 Eruption
 
Merapi, as one of the active volcanoes in Indonesia, become a threat to the surrounding settlements. Especially large eruption that happened in the 2010  which created crater openings that increased the potential for eruptions leading to Pangukrejo Village, as one of it's area. On the other hand, Pangukrejo Village included in the Disaster-Prone Area III (KRB III) but refused to be relocated. After the 2010 eruption, people realized that they need not only local wisdom but also mitigation efforts by government. Until now, both local wisdom and disaster mitigation have worked together to increasing the preparedness of the people in this village to face future eruptions of Merapi. This study aims to identify local wisdom that still being carried out and worked together with disaster mitigation in Pangukrejo Village, which reviewed from the physical aspects, such as zone planning, early warning systems, and building design. The research use descriptive qualitative method with data analysis using content analysis technique and choosing respondents using purposive sampling technique. Based on the results of the research, it was finally found that there are the same meanings and interrelated key patterns that make local wisdom still being carried out and worked together with disaster mitigation.
THE USE OF NINTEDANIB IN THE TREATMENT OF POST-COVID-19 FIBROSIS
Authors: Saroukh F. , Mourouth H. , Ribahi H. , Eladib G.
Published: September 2022

Pulmonary fibrosis is becoming a recognized complication of coronavirus disease 2019 (COVID-19). We report 2 cases of 2 patients aged 40 and 61 with pulmonary fibrosis due to COVID-19. The clinical examination showed that the 2 patients were dyspneic with a weak oxygen saturation and that there was bilateral crackles of the two pulmonary fields. High-resolution computed tomography showed bilateral multifocal ground glass opacities, subpleural fibrotic bands (between 25-50% and 75% parenchymal involvement). We prescribed them an anti-fibrosant, nintedanib, and there was a significant clinical and radiological improvement after 15 days of treatment. Nintedanib may have a new therapeutic role in the prevention of fibrosis associated with COVID-19.
EPISTEMOLOGY IN MIGRANT COMMUNITY FOR BETTER HEALTH OUTCOMES IN PRIMARY HEALTH CARE OF NORTH INDIA - A CASE STUDY
Authors: Gupta Atul , Ashish Jindal Har
Published: September 2022

The migrant community often lacks health care access due to poor health knowledge. Epistemology deals with the nature and scope of knowledge. Epistemology links the migrant community to health system with adequate knowledge to accept the health seeking behavior in lifestyle. Objective: To assess thesalutogenic health promotion model in primary health care for the migrant population. Methods: A qualitative analysis in the migrant community was conducted in a family with an antenatal case as the index case. The epistemological salutogenic health model of General Resistance Resources (GRR) and Sense of Coherence (SOC) was applied. A health promotion model was devised in accordance to the GRR and SOC. A health system intervention was also planned to improve health indicators. Results: The family had a better approach towards heath and preparedness towards the institutional delivery of the child. The children were immunized with appropriate documentation. The success story of the family turned the migrant community to act as a social support group for positive health. There were improvements in the health indicators of the urban slum improved. Conclusion: Usingepistemology aspects and salutogenic health promotion model bridged the gaps in the health system with the migrant community. The migrant community are often ignorant towards their health but with appropriate health promotion models their health needs can be addressed.
PANDEMIC AND CORPORATES TRATEGY: TOOLS & DIAGNOSIS
Authors:   Professor of Higher Education, Faculty of Economic, Legal and Social Sciences, Oujda, Morocco., Ouchen Imane , Bekkaoui Sophia ,   Professor of Higher Education, Faculty of Economic, Legal and Social Sciences, Oujda, Morocco.
Published: September 2022

The COVID-19 pandemic has taken a heavy toll on business dynamism. Although business entry has rebounded from the drop seen during the initial confinements in early 2020, this recovery varies widely across countries, with potential long-term implications for employment and output growth. Inflows have fallen less in sectors characterized by high information and communication technology (ICT) intensity and a relatively high propensity to telework, while they have fallen more sharply in those that rely more on physical contact with customers.The experience of two consecutive years with the exceptional event of the health crisis has led companies and institutions to face the Covid-19 challenge quickly by implementing new procedures and managerial practices. To fuel the debate on the problem of the crisis and its lasting repercussions on the management of organizations, we ask the question What could be the lasting repercussions of the crisis on the management? What will be the new strategies of companies?
LORSQUE LE VACCIN COVID-19 ATTAQUE LE COEUR : A PROPOS DUN CAS ET REVUE DE LA LITTERATURE
Authors:   Departement De Cardiologie Et Maladies Vasculaires, Centre Hospitalo-Universitaire Mohamed VI, Marrakech, Maroc., Atidi M. , Zahid FZ. ,   Departement De Cardiologie Et Maladies Vasculaires, Centre Hospitalo-Universitaire Mohamed VI, Marrakech, Maroc., Eljamili M. ,   Departement De Cardiologie Et Maladies Vasculaires, Centre Hospitalo-Universitaire Mohamed VI, Marrakech, Maroc., Elhattaoui M. ,   Departement De Cardiologie Et Maladies Vasculaires, Centre Hospitalo-Universitaire Mohamed VI, Marrakech, Maroc.
Published: September 2022

Des le debut de la pandemie de COVID-19, le cÅ“ur etait identifie comme une cible de choix du coronavirus.Actuellement, la polemique a propos des vaccins anti-covid decoule de la constatation des cas de myocardite/pericardite, apres ladministration de vaccin a ARNm. Nous rapportons le cas dun jeune patient, qui sest presente aux urgences pour des douleurs thoraciques retro sternalesevoluant 6 jours apres avoir reÃ§u, sa 2eme dose de vaccin contre laCOVID-19. Apres avoir elimine les autres etiologies, le diagnostic dune myocardite post vaccinale etait retenu. Les avantages des vaccins contre la COVID-19 continuent de lemporter sur les risques de cette infection virale, en depit des effets secondaires signales.
COMPARATIVE VARIATION OF RESULTS IN MANAGEMENT OF EXTRAARTICULAR DISTAL TIBIAL FRACTURES BY INTRAMEDULLARY NAILING VS MINIMAL INVASIVE PLATE OSTEOSYNTHESIS
Authors:   Assistant Professor, Department of Orthopaedics, Governement Medical College, Orai, Jalaun., Banoria Gaurav
Published: September 2022

Background: Distal metadiaphysealtibial fractures are commonly seen lower limb fractures. Intramedullary nail fixation (IMN) and Minimal invasive plate Osteosynthesis (MIPO) are the two mainstay treatments for tibial fractures, but agreement on the best internal fxation for distal tibial fractures is still controversial. This meta-analysis was designed to compare the success of IMN and MIPO fxations in the treatment of distal metadiaphysealtibial fractures, in terms of complications and functional recovery Aims: To evaluate the results of management of distal tibial fractures by Intramedullary nail and minimal invasive plate osteosynthesis Methods: The present study will be conducted on patients attending Emergency and outpatient department of Orthopaedics, GovernmentMedical College, OrailJalaun, UttarPradseh for the period of January 2019 to July 2021. A minimum of 30 cases will be taken in the study those who are fracture distal tibia. Result: In my thesis, we take total 60 patient which divided into two group of 30-30 patients. Group One for In Minimal invasive plate Osteosynthesis (MIPO) and Group Two for Intramedullary nail. Only signifcant difference seen in my study in length of incision in nailing length of incision is less as compare to plating group Conclusion:The study of management of distal tibia fracture by MIPO and IMN. I found that no significant difference in final result. In MIPO group only 2 patient have superficial infection and IMN group only 1 patient has superficial infection that means the rate of infection more in plating as compare to nailing.
DOWEL PIN - SNAP FIT TECHNIQUE: A NOVEL SPLIT CAST TECHNIQUE
Authors:   Department of Prosthodontics, Yenepoya Dental College, Yenepoya University, Mangalore, India., Shetty R. , Thenukutty F. ,   Department of Prosthodontics, Yenepoya Dental College, Yenepoya University, Mangalore, India., Dilip N. ,   Department of Prosthodontics, Yenepoya Dental College, Yenepoya University, Mangalore, India., Harini K. ,   Department of Prosthodontics, Yenepoya Dental College, Yenepoya University, Mangalore, India., Shetty S. ,   Department of Prosthodontics, Yenepoya Dental College, Yenepoya University, Mangalore, India., Rauf R. ,   Department of Prosthodontics, Yenepoya Dental College, Yenepoya University, Mangalore, India.
Published: September 2022

Complete denture construction comes with a lot challenges both during the clinical and laboratory steps. Lab remounting is one of those steps it is done to mount the master cast back in position after acrylisation of the complete denture to undergo selective grinding. But the conventional methods used for this technique have not been good enough to hold the master cast in place in a stable manner. The novel technique introduced in this article uses dowel pins for remounting, and it provides a more stable, reliable and snug fit technique without making the technique any more complicated.
THE IMPACT OF EDUCATIONAL TECHNOLOGY ON THE STRESS LEVEL OF PARENTS OF AUTISTIC CHILDREN
Authors: Eller Todd
Published: September 2022

A recent survey by the American Psychological Association (2020) shows that parents have a stress level of 6.7 out of 10 compared to that of 5.5 for single adults. Also, anxiety among parents of autistic children is nearly twice that of parents of mainstream children (Padden & James, 2017). There have been many suggested antidotes to stress including therapy and medication. However, there has been some preliminary evidence that creative projects can reduce stress-related symptoms (Lewis, 2016). The following study was an attempt to determine if an educational app that has been shown to increase independence with autistic children would reduce stress among parents as compared to group therapy and a control group. The setting was the homes of autistic children with an average of 9.1 years of age. Thirty children (22 males, 8 females) had previously participated in a study involving the iCAN educational appor used a traditional worksheet educational platform. Parents were given a stress survey before and after this study with 46 parents participating (28 female, 18 male) with an average age of 34.2 years. The children and the parents were then randomly assigned to either a traditional worksheet instructional group or an app educational group. Both groups of parents and children received a single one week instruction by certified instructors via the web and parents were guided by behaviorists on how to train their children using the materials.
QUALITY FRAMEWORKS WORLD OVERAND ISSUES FOR INDIA
Authors:   Associate Professor Government College of Education, Mumbai, MH, IN., Urmila Paralikar
Published: September 2022

Delivering Quality Education is the fundamental duty of teaching fraternity. Quality assessment is the key to ensuring progress in educational systems that are composed of components like Teachers, Students, Curriculum, Transactional processes, assessments This paper examines the various Quality frameworks forthese components of Education existing the world over and compares them with those existing in India. This is a descriptive study done with the objective of studying the various quality frameworks in place in different countries motivating the educationists and thinkers in India to develop even more fortified Quality Frameworks extensively and intensively for the areas not yet addressed such as Content development standards, Teacher Induction Standards, Teacher Professional Standards, Continuous Teacher Development Standards etc.
Ética profesional en la formación del estudiante de psicología de educación a distancia
Authors: Alvites-Huamaní Cleofé Genoveva
Published: September 2022

La ética profesional en la formación del estudiante de psicología es inherente a su futura praxis como psicólogo, y por ende las instituciones de educación superior están obligadas a impartirla como un curso obligatorio o de no ser posible, como talleres o diplomados, para que los estudiantes integren sus conocimientos con la ética y deontología profesional. Es por lo que en la disertación que se presenta de manera descriptiva en este artículo, además de la revisión de la literatura, se presenta de forma detallada la implementación del taller de ética y deontología profesional en psicología de la modalidad de educación a distancia de la Universidad Alas Peruanas de la Dirección de Educación a Distancia, en el periodo del 2010 al 2012 en la Coordinación de la Escuela Profesional de Psicología Humana.
Cezâyir-i Bahr-i Sefîd Vilayeti 3.Bölge’de Madenler ve (Yurtdışına Akan Sermaye )
Authors: BAYKARA TAŞKAYA Arzu
Published: September 2022

Abstract :Eyalet of the Archipelago, one of the most important provinces of the Ottoman Empire, had sanjaks consisting of the islands of Lemnos, Mytilene, Rhodes and Chios. The minerals that we will describe, although their boundaries have changed over time, are discussed in the area covering this geography. After being operated by the state during the classical period, Ottoman minerals became the focus of attention of domestic and foreign investors from the second half of the 19th century. Many of the minerals in the province we have discussed have not yet been fully determined. We see that foreigners generally aspire to minerals on the islands opened for operation. Although the state did not find it appropriate to give the operation of the mines to foreigners; determined the conditions in the specifications and regulations and granted the mining concessions. The salterns in the sanjaks were also determined. Although the operating conditions and tax rates of the mines were determined by the state, some of the mines were not operated and the state canceled the privilege of the mines in cases where taxes were not paid. In the article, all kinds of documents reflected in the archive regarding the locations, usage areas, operating privileges, taxation, export areas of the minerals in the Eyalet of the Archipelago are explained in the traces of the documents found in the Ottoman Archives of the Presidency State Archives. In the article, the material wealth of the Ottoman Empire flowing abroad with the privileges given to foreigners in the context of mines, which was one of the basic wheels of the economy, from the sanjaks to the villages and the connected islands is also mentioned. Keywords: Eyalet of the Archipelago, Lemnos - Mytilene - Rhodes and Chios Sanjaks , Mines, Contracts, Foreign Concessions.
Pengembangan Game Quartet Card Pada Materi Klasifikasi Makhluk Hidup Kelas VII SMP/MTs
Authors: Kurniawan Rivo Alfarizi , Hasanah Rafiatul
Published: September 2022

Materi IPA yang dianggap sulit yakni klasifikasi makhluk hidup, hasil angket menunjukkan sebesar 58,3% siswa kesulitan belajar klasifikasi makhluk hidup dikarena media yang digunakan tidak sesuai dengan gaya belajar. Penelitian bertujuan (1) mengembangkan game quarted card, (2) mendeskripsikan validitas dan respons siswa terhadap game quarted card. Jenis penelitian yaitu penelitian dan pengembangan model ADDIE Sugiyono. Hasil pengembangan media berupa game quarted card, hasil validasi ahli materi diperoleh sebesar 95%, validasi ahli media diperoleh 94% validasi pengguna diperoleh sebesar 96,5% kriteria sangat valid. Hasil uji coba skala kecil diperoleh 93% dan hasil uji coba skala besar diperoleh 92% sebesar kriteria sangat menarik artinya dari segi keterbacaan dan kemenarikan game quarted card sangat baik.
Desafios da aldeia indígena Maracanã/RJ e a resposta do “Constitucionalismo Democrático Latino Americano”
Authors: Balmant Emerique Lilian Márcia , Khattar Semirames , De Oliveira Wagner Vinicius
Published: September 2022

Este artigo movimenta algumas questões referentes à participação política indígena de acordo com as bases teóricas do “constitucionalismo democrático latino americano”. O objetivo central consiste em compreender parcela dos desafios da experiência constitucional brasileira tendo em vista as disputas pelo território da aldeia indígena Maracanã localizada na cidade do Rio de Janeiro/RJ. Busca-se identificar como essas tensões sociais e jurídicas se materializam e as dificuldades impostas pelas utilizações autoritárias dos elementos de origem popular. Para tanto, utiliza-se a revisão de literatura e a análise documental para identificar as respostas que o marco teórico e as práticas institucional e social brasileiras oferecem. Chega-se à conclusão de que as práticas analisadas dificultam a compreensão e o tratamento adequado da questão territorial indígena.
Gestión y organización universitaria para enfrentar la pandemia de COVID-19. Aportes desde la universidad pública en Colombia
Authors: Bedoya-Dorado Cristian , Murillo-Vargas Guillermo , González-Campo Carlos Hernán
Published: September 2022

El presente artículo analiza la gestión universitaria desarrollada en una institución pública en la etapa inicial de la pandemia y durante esta en Colombia en 2020. El método de estudio de caso fue utilizado para iden­tificar las estrategias implementadas por la institución para afrontar la crisis a partir de la planeación, la gestión académica, la gestión administrativa, la gestión del bienestar, la gestión de la investigación, y la extensión. Los resultados permiten evidenciar una configuración de la gestión universitaria que se orientó principalmente a garantizar los procesos de enseñanza y pre­sencialidad asistida por tecnología, a apoyar económica y psicológicamente a los estudiantes mediante estrategias de articulación con otras entidades, y a soportar la crisis nacional mediante la investigación y el conocimiento de los académicos.
Diagnostic Evaluation of Chronic Thromboembolic Pulmonary Hypertension
Authors: Vaidya Anjali , Forfia Paul R.
Published: September 2022

Chronic thromboembolic pulmonary hypertension (CTEPH) is a distinct form of pulmonary hypertension, uniquely characterized by pulmonary artery narrowing and occlusion from clot material. With advances in medical education and therapeutic options, awareness of CTEPH has grown significantly in recent years. The diagnostic evaluation remains complex, warranting an integrated assessment of history, physical exam, echocardiogram, chest imaging including computerized tomography with angiography, ventilation–perfusion scanning, right heart catheterization, catheter-based pulmonary angiography, and assessment for medical and mechanical CTEPH risk factors. The diagnostic evaluation of CTEPH is reviewed here.
Contribuição à morfologia polínica de plantas medicinais apícolas (Euphorbiaceae Juss. & Lamiaceae Martinov)
Authors: Enderlei Dec  , Denise Monique Dubet da Silva Mouga
Published: September 2022

Em função da variabilidade dos tipos polínicos, sua descrição morfológica constitui suporte para diversas finalidades e estudos. Estão descritas neste trabalho 13 espécies polínicas de interesse apícola, sendo seis da família Euphorbiaceae (Euphorbia milii des Moul., E. pulcherrima Willd. ex Klotzsch, Jatropha curcas L., J. gossypiifolia L., J. multifida L. e Ricinus communis L.) e sete de Lamiaceae (Solenostemon scutellarioides (L.) Codd., Mentha x villosa Huds., Ocimum basilicum L., O. gratissimum L., Plectranthus grandis (L. H. Cramer) R. Willemse, P. neochilus Schlechter e Tetradenia riparia (Hochst.) Codd.). Os grãos foram preparados por acetólise, fotografados e caracterizados quanto a tamanho, forma, aberturas e ornamentação externa. A família Euphorbiaceae mostrou-se euripalinológica com grãos isopolares, de simetria radial, próximos da forma esferoidal, 3-colporados ou atremados (gênero Jatropha), com endoaberturas lalongadas em Euphorbia milii, E. pulcherrima e Ricinus communis, além de exina variando entre fina e espessa, bem como ornamentação reticulada, exceto para Ricinus (psilado). Em Lamiaceae, os grãos apresentaram-se isopolares, com simetria radial, formas que variavam de oblato a prolato, 6-colpados, com exina pouco variável, ornamentação sempre reticulada, sem endoaberturas, caracterizando uma família estenopalinológica.
O gênero Peperomia Ruiz & Pav. (Piperaceae) na Serra da Tiririca, Rio de Janeiro, Brasil
Authors: George Azevedo de Queiroz  , Elsie Franklin Guimarães  , Ana Angélica Monteiro de Barros
Published: September 2022

O gênero Peperomia Ruiz & Pav. possui cerca de 1.700 espécies e apresenta hábito terrestre, epífito ou rupícola, com folhas alternas, opostas ou verticiladas. O estudo foi realizado na Serra da Tiririca (22º48’-23º00’S; 42º57’-43º02’W), um remanescente de mata atlântica (floresta ombrófila densa submontana) de 2.260hectares, localizado na divisa dos municípios de Niterói e Maricá (RJ), com o objetivo de levantar as espécies do gênero presentes na área. Fizeram-se coletas de plantas férteis no período de 2011 a 2014 e analisaram-se as exsicatas dos herbários GUA, HB, R, RB, RBR, RFA, RFFP, RUSU e FCAB. Na área foram encontradas sete espécies: Peperomia arifolia Miq., P. corcovadensis Gardner, P. incana (Haw.) A. Dietr., P. urocarpa Fisch. & Mey., P. psilostachya C. DC., P. rubricaulis (Nees) A. Dietr. e P. tetraphylla (G. Forst.) var. tetraphylla. Destaca-se como endêmica da floresta atlântica Peperomia incana, comum em afloramentos rochosos no interior da mata. São apresentadas chave de identificação e descrição de cada espécie, assim como ilustrações e dados sobre sua fenologia e distribuição.
Produção e qualidade de mudas de Psidium cattleianum var. cattleianum Sabine (Myrtaceae) em diferentes substratos
Authors: Alan Richar Freitas Marques  , Viviane da Silva Oliveira  , Alexandra Augusti Boligon  , Silvane Vestena
Published: September 2022

Analisou-se o uso de lodo de esgoto como substrato na produção de mudas de Psidium cattleianum var. cattleianum Sabine. Os tratamentos foram: T1 (50% substrato comercial Plantmax® + 50% cama de equino, tido como composto orgânico), T2 (20% lodo de esgoto + 80% composto orgânico), T3 (40% + 60%) e T4 (60% + 40%). Os tratamentos foram arranjados em delineamento inteiramente casualizado, com cinco repetições por tratamento com 50 sementes cada. Os dados foram submetidos à análise de variância e as médias discriminadas pelo teste de Tukey a 5% de probabilidade. A cada três dias, durante 90 dias, realizou-se a contagem de plântulas que emergiram, para posterior cálculo de índice de velocidade de emergência. Decorridos 180 dias após a semeadura, foi calculada a porcentagem de emergência, foram verificadas as características biométricas e foi calculado o índice de qualidade de Dickson. A utilização do substrato comercial associado a cama de equino proporcionou as menores médias para todas as características avaliadas. Os tratamentos com lodo de esgoto associado ao composto orgânico apresentaram os melhores resultados para as características morfológicas avaliadas, sendo o tratamento 3 aquele com os melhores resultados.
Avaliação qualitativa da arborização com Mangifera indica nas ruas de Belém – PA
Authors: Dâmaris Araújo da Silva  , Daniela Biondi Batista  , Antônio Carlos Batista
Published: September 2022

O objetivo deste trabalho foi caracterizar a arborização das ruas com mangueira no Distrito Administrativo de Belém, localizado na cidade de Belém, PA. A pesquisa foi desenvolvida com levantamento quantitativo de mangueiras plantadas nas ruas urbanizadas. Para tanto, as variáveis avaliadas foram: caracterização do espaço físico, condições de copa e raiz e danos físicos. As distâncias das estruturas urbanas das mangueiras foram consideradas adequadas, porém houve incompatibilidade entre a projeção da rede aérea com o porte das mangueiras. Considerou-se regular a condição de copa em estado geral (68,5%), enquanto 57,56% das mangueiras apresentaram raízes semissuperficiais. Verificou-se que 22,03% dos entrevistados tiveram participação na manutenção das mangueiras. Constatou-se ainda que 70% dos entrevistados perceberam pelo menos dois danos nas árvores. Notou-se a necessidade de implementar podas regulares para melhorar o ambiente urbano e, consequentemente, a qualidade de vida da população.