bluuebunny/crossref_metadata_2025 huggingface dataset:
Estudo da produção científica sobre o enfoque CTS em revistas brasileiras especializadas
Authors: Moreno Rodríguez Andrei Steveen , Del Pino José Claudio
Published: July 2019

O estudo teve como objetivos principais: mapear, classificar e analisar descritivamente produções científicas acerca do enfoque Ciência, Tecnologia e Sociedade – CTS, publicadas entre 2011 e 2015 em revistas brasileiras. Foram selecionadas 4 revistas especializadas nas áreas de Ensino e Educação, classificadas com Qualis A1 e A2. Por meio da leitura de títulos e resumos dos 803 artigos publicados nesse período, foram escolhidas 30 publicações para serem analisadas. As principais informações bibliométricas desses textos foram sistematizadas em formato de tabela e os documentos completos dispostos em uma unidade hermenêutica do software ATLAS.ti para posterior análise. A partir de critérios bibliométricos e da leitura completa dos textos foi possível identificar: 1) interesse dos pesquisadores por trabalhar no campo da Educação em Ciências e pela formação de professores; 2) interesse pela abordagem de questões sociocientíficas; 3) tendência à realização de intervenções didáticas e estudos de caso; 4) interesse por conhecer percepções da comunidade acadêmica acerca de ciência e de tecnologia, assim como pelas dificuldades para a implementação de atividades CTS. Concluiu-se que nos últimos anos tem sido consolidado um conjunto de referências brasileiras que discutem o tema, gerando, consequentemente, uma forma particular de pensar o enfoque CTS. No entanto, percebeu-se a necessidade de aproximar essa produção com estudos realizados nos países vizinhos para, dessa forma, contribuir para a construção de uma perspectiva latino-americana de progresso educativo, social e tecnocientífico.
“Oi, Quem está olhando minhas estatísticas?” – Uma discussão do desempenho de estudantes da Educação Básica sobre média aritmética
Authors: Luna Luan Costa de , Carvalho José Ivanildo Felisberto de
Published: July 2019

Neste artigo analisamos e discutimos o desempenho de estudantes do Ensino Fundamental e Médio de uma escola privada da Região Metropolitana de Recife-PE sobre o conceito de média aritmética. Para tanto, foi elaborado um teste diagnóstico com cinco questões, as quais traziam diferentes significados desse conceito em situações com e sem representação gráfica. Os resultados mostram que o nível de escolaridade foi um fator determinante no desempenho deste grupo de estudantes, entretanto abaixo do esperado. No que tange aos diferentes significados do campo conceitual da média aritmética, observamos que os estudantes apresentam dificuldades na compreensão dos referidos significados.  Constatamos que a representação gráfica influenciou dificultando no desempenho dos estudantes. Quanto às estratégias de resolução, identificamos que os estudantes concebem equivocadamente a média aritmética como sendo: soma de um conjunto de valores; um número que é dividido por dois; o termo central de um conjunto de valores disposto em ordem crescente (mediana); e/ou um número terminado em zero. Além disso, percebemos que apresentaram dificuldades com o cálculo da divisão. Por meio deste estudo esperamos subsidiar o trabalho do professor para abordar em suas aulas de matemática o conceito de média aritmética considerando os diferentes significados que sustentam este conceito.
Problemas identificados em gráficos estatísticos publicados nos meios de comunicação
Authors: Santos Rodrigo Medeiros dos , Branches Messias Viana
Published: July 2019

O objetivo desta pesquisa é abordar e analisar alguns exemplos de erros contidos em gráficos estatísticos publicados nos meios de comunicação, buscando a construção de subsídios para a interpretação e análise crítica dessas ferramentas no contexto das práticas de letramento estatístico. A pesquisa tem como principal aporte teórico as ideias sobre letramento estatístico de Iddo Gal.  Metodologicamente, a pesquisa é caracterizada como descritiva e bibliográfica. Os principais resultados apontam diversas impropriedades na construção dos gráficos, tais como a ausência do eixo das ordenas, barras dos gráficos com larguras e comprimentos desproporcionais, incompatibilidade dos rótulos dos dados com as medidas apresentadas nos gráficos, entre outros. Os resultados nos levam a ressaltar a necessidade de uma sociedade estatisticamente letrada, bem como nos chama a atenção para a necessidade de uma formação estatística mais adequada para os profissionais da imprensa.
NOTAS SOBRE A FORMAÇÃO DOCENTE O SABER HISTÓRICO ESCOLAR NOS CURSOS DE FORMAÇÃO DE PROFESSORES DE HIST
Authors: Coelho Mauro Cezar , Coelho Wilma De Nazaré Baía
Published: July 2019

O artigo aborda a formação docente, tendo em vista o espaço destinado ao saber escolar nos cursos de formação de professores de História. Para tanto, analisa os saberes que concorrem para a docência, cujo objetivo é demarcar as três competências que o professor deve compreender: o saber de referência, o saber sobre os processos de ensino-aprendizagem e o saber sobre os sujeitos com os quais interage. Nesse sentido, os autores consideram a legislação que reformula a perspectiva nos currículos da Educação Básica e os processos de formação de professores de História, de modo a perceber o lugar ocupado pelas discussões acerca das questões que interessam à Escola, seus agentes e o saber ali operado. Concluem que o saber docente não apenas cumpre função periférica nos processos de formação, como assumem um sentido meramente instrumental, o que denota uma fragilidade na formação docente em história na dimensão pedagógica.
DA EDUCAÇÃO RURAL A EDUCAÇÃO DO CAMPO: UMA REFLEXÃO NECESSÁRIA
Authors: Scalabrin Rosemeri
Published: July 2019

Este artigo discute sobre a educação do campo, no sentido de localizá-la historicamente e identificar as concepções que marcaram cada época, bem como as práticas pedagógicas desenvolvidas no Campus Rural de Marabá no período de 2010-2016. Para isso, realizou-se a pesquisa bibliográfica e documental, composta pelo estudo do Projeto político pedagógico e relatórios tanto da formação continuada quanto da avaliação institucional e docente. O resultado da pesquisa aponta, de um lado, avanços construídos coletivamente no âmbito da educação interdisciplinar e integrada e, de outro, lacunas vivenciadas no decorrer deste percurso, bem como aponta elementos necessários ao resgate da materialidade de origem da proposta pedagógica institucional que se sofreram mudanças fruto do processo de institucionalização da educação do campo.
Potencial de captação de água de chuva em unidades familiares rurais do município de Breves-PA
Authors: Freires Evelyn Lopes , Mendes Herbert Maracaípe , Mendes Ronaldo Lopes Rodrigues , Ramos Francisca Correa Dias
Published: July 2019

A zona rural da Amazônia possui uma particularidade muito grande, principalmente nas comunidades ribeirinhas: geralmente são caracterizadas pela carência de saneamento básico. No cenário paraense, cerca de 60% dos municípios apresentam sistema de abastecimento ineficiente, decorrente de dificuldades na oferta de água nos mananciais, em quantidade e/ou qualidade (ANA, 2010). O presente estudo visa avaliar o potencial de aproveitamento doméstico da água da chuva em unidades familiares de áreas rurais do município de Breves. A metodologia utilizada se pautou inicialmente um uma pesquisa exploratória, a partir do material bibliográfico e documental. Assim, a escala espacial da pesquisa abrangeu as unidades familiares rurais existentes no município de Breves, pertencente à mesorregião do Marajó, no Pará, do qual buscou-se calcular o potencial de aproveitamento da água pluvial, considerando os seguintes dados de precipitação mensal; área de captação total; e população rural (Ghisi et al., 2006). Além disso, o volume de precipitação a ser coletado variou entre 84,9m³/mês a 1580,90 m³/mês, revelando como grande potencial em comunidades rurais, o aproveitamento doméstico a partir da captação da água pluvial, como forma de sanar a carência do acesso ao recurso hídrico para consumo humano.
PEMBENTUKAN PERATURAN DAERAH PERSPEKTIF GENDER (ANALISIS TERHADAP PEMBENTUKAN PERATURAN DAERAH PERSPEKTIF GENDER DI PROVINSI NUSA TENGGARA BARAT KURUN WAKTU 2013-2016)
Authors: Sidiq Gazali
Published: July 2019

The main problem for seeking the substance of legislation includes technical operational policies that are sensitive and responsive to various problems in society, including the issue of gender inequality practical and strategic steps to create and realize legislation whose content is sensitive and responsive to gender so that everything the problems and aspirations of the community can be accommodated in a form of regulation that is also gender responsive. Integrating gender perspective into legislation to realize prosperity.  The aim is envisioned by the wider community. The legislation can be in the form of a law along with its implementing regulations and regional regulations along with the implementing regulations.

 Keywords : Hakam, Pengadilan Agama, Mahkamah Syar’iyyah.
PERLINDUNGAN TERHADAP PENCARI SUAKA DAN PENGUNGSI MENURUT HUKUM ISLAM DAN HUKUM INTERNASIONAL (STUDI FILOSOFIS DAN ONTOLOGIS KEILMUAN)
Authors: Syahrin Muhammad Alvi
Published: July 2019

The problem of refugees and the displacement of people in the country is the most difficult problem facing the world community today. Many discussions were held at the United Nations which continued to seek more effective ways to protect and assist these very vulnerable groups. Some people call for increased cooperation and coordination between aid agencies, others point to gaps in international regulations and call for further standards in this field. However, everyone agrees that this problem is a global and global problem. Therefore every approach and solution must be carried out comprehensively and explain all aspects of the problem from the causes of mass exodus to the elaboration of the necessary responses to overcome the range of problems of refugees from emergencies to repatriation. This study will discuss how the basic rules of protection for asylum seekers and refugees according to Islamic law and international law.
On random equilibrium points
Authors: Obukhovskii Valeri , Getmanova Ekaterina , Karpov Michael
Published: July 2019

We present a random version of a theorem on equilibrium points for two parametrized multivalued maps satisfying a joint Caristi type condition.
On exact triangle inequalities in (q1, q2)-quasimetric spaces
Authors: Zhukovskaya Zukhra , Zhukovskiy Sergey , Sengupta Richik
Published: July 2019

For arbitrary (q1, q2) -quasimetric space, it is proved that there exists a function
f, such that f -triangle inequality is more exact than any (q1, q2) -triangle inequality. It is
shown that this function f is the least one in the set of all concave continuous functions g
for which g -triangle inequality hold.
Projective congruent symmetric matrices enumeration
Authors: Starikova Olga. A
Published: July 2019

Projective spaces over local ring R = 2R with principal maximal ideal J; 1+J ⊆ R*2 have been investigated. Quadratic forms and corresponding symmetric matrices A and B are projectively congruent if kA = UBU T for a matrix U ∈ GL(n;R) and for some k ∈ R * : In the case of k = 1 quadratic forms (corresponding symmetric matrices) are called congruent. The problem of enumerating congruent and projective congruent quadratic forms is based on the identification of the (unique) normal form of the corresponding symmetric matrices and is related to the theory of quadratic form schemes. Over the local ring R on conditions R * =R *2 ={1;-1; p;-p} and D(1; 1)=D(1; p)={1; p}; D(1;-1)=D(1;-p)={1;-1; p;-p} (unique) normal form of congruent symmetric matrices over ring R is detected. Quantities of congruent and projective congruent symmetric matrix classes is found when maximal ideal is nilpotent.
Marital Satisfaction amongst Nigerian Immigrants in North America (NINA): Pilot Study
Authors: Ade-Oshifogun Jochebed B. , Aina Joan , Olaore Augusta
Published: July 2019

Background: It has been observed that some Nigerian Families that immigrated to North America (NINA) seem to have very stressful marital relationships that lead to separation or divorce. The goal of this study was to determine the level of marital satisfaction among NINAMethod: A simple, standardized survey tool was utilized to measure the index of marital satisfaction (IMS). The score varied from 0-100 with a lower score (<30 points) indicating marital satisfaction. A demographic questionnaire was also administered to the subjects. Descriptive data analysis and level of marital satisfaction were computed in SPSS (version 25).Results: Forty-five of the fifty questionnaires were returned completed. Fifty-one percent of respondents were female. The majority (44%) were between the ages of 41-50 years. 81% were married and living with spouses. Average year of marriage was 13.5 years. The majority (85%) of respondents were married in Nigeria with only one spouse immigrating first (35%). The primary reason for immigration was employment for most subjects (48%). Seventy-two percent of the respondents scored < 30 on the IMS scale, indicating marital satisfaction. The scores were not significant when compared within the demographic variable groups. Most participants (71.4%) reported significant marital satisfaction (Z=-3.209, p=0.001. r = 0.47).Conclusion: Initial pilot study did not support the observation in the Nigeria community regarding stressful marital relationships among NINA. The IMS tool may not be sensitive to the Nigerian marriage culture and possible factors affecting marital satisfaction with cultural influence. The authors plan to conduct a more extensive study with a qualitative approach to elicit the Nigerian culturally sensitive factors.
Financial Performace and Systemic Risk Effect On Stock Return (Case Study on Oil and Gas Companies Listed In IDX Year 2011-2016)
Authors: Hertina Dede , Hidayat Mohamad Bayu Herdiawan
Published: July 2019

This study aimed to determine whether the return on assets, debt to equity ratio, and systematic risk effected on stock returns on oil and gas companies listed on the Stock Exchange period 2011-2016. The research method used was descriptive method verifikatif with research sample as much as 5 oil and gas company. The technique of selecting the sample used purposive sampling, while the method of analysis used was analaisis regresi panel data at significance level 5%, by using Eviews9. Partial result shows that Return On Asset was not influential to stock return and DER have negative and significant effect to stock return, while Beta had positive and significant effect to stock return and simultaneously Return On Asset, DER, and beta have positive effect to stock return.
Zakat Produktif Sebagai Modal Kerja Usaha Mikro
Authors: Bahri Efri Syamsul , Oktaviani Reni
Published: July 2019

Zakat is a duty ordered directly by Allah in the Qur'an. Zakat is well managed and able to empower mustahik as well as be a solution in alleviating poverty. The focus of this research is how to describe productive zakat as a micro business work capital and what are the benefits of productive zakat as working capital for mustahik? The purpose of this research is to dig deeper the model of productive utilization of zakat as working capital of micro business. The method used in this study is a qualitative method with a descriptive approach that describes a condition or fact finding with appropriate interpretation. The results of this study indicate that zakat institutions that apply the productive zakat model as a micro business work capital to be hope in improving social status mustahik be muzaki. Zakat as working capital is beneficial for empowering micro business, improving micro business business, growing spirit, improving ability and skill and entrepreneurship. Viewed from the socio-economic aspects of zakat can encourage the growth of the weak economy by increasing their purchasing power to increase employment and micro business income. Viewed from the moral-spiritual aspect of zakat is a means to increase obedience and servitude to God. Thus the productive zakat model as working capital becomes an effective way to alleviate poverty.
Analisis Determinan Makro Ekonomi Pada Beberapa Negara Asia dalam Memepengaruhi TKI Tahun 2011-2015
Authors: Purba Matius Inganta , Yuhan Risni Julaeni
Published: July 2019

Asia is the country with the largest number of TKI placement. However, from 2012 there was a decrease in the number of overseas placement for Indonesians even in the four year interval there was a decrease up to 52.66 percent including in Asian countries. One of the causes of the decline of labor migrants is due to the revamping of the placement of informal TKI in some countries, especially in the middle east region so that the number of migrant workers is very small. In fact, the remittance of migrant workers is one of the largest foreign exchange contributors in Indonesia. In 2011, the value of remittance reached 60 trillion or the second highest contributor of foreign exchange. Of course with the existence of such remittances can support the Indonesian economy. The purpose of this study is to see what variables that influence in the process of placement of overseas workers especially in some countries in Asia continent based on economic condition of destination country. Analytical techniques used are panel data analysis with inflation variable, per capita income, unemployment rate, and exchange rate of destination country. The results of this study indicate that the variables of inflation, income per capita, and unemployment rate in influencing the number of placement of labor migrants in the destination country.
Analisis Strategi Pengembangan Zakat, Infaq, Shadaqoh dan Wakaf di Indonesia
Authors: Lubis Rusdi Hamka , Latifah Fitri Nur
Published: July 2019

This study to describe the picture of ziswaf potential and Ziswaf's realization in Indonesia explained the difference between potential and realization. Beginning with a quantitative descriptive approach method by collecting secondary data from various sources. A very large gap between the value of potential and the amount of realization. During the last five years until 2016.  The realization of zakat receipts was only less than 1%. The development of Ziswaf funds in Indonesia must have strategic objectives that must be reduced in the policies of all stakeholders. Thus, muzakki and mustahik are important components in the development and succession of empowerment. The selection of the right strategy can be done using the SWOT analysis method to produce a condition map of the research group and the right strategy to support the strategic objectives. The results of the analysis show that Ziswaf's condition in Indonesia has experienced and significant development. The results of the analysis also show that there are 6 (six) strategies that can be used to achieve Ziswaf's strategic objectives, namely: (1) digitizing of Ziswaf, (2) Islamic Inclusive Finance Council, (3) Database Development, (4) Regulation Implementation, (5) Zakat Automation, (6) Tax incentives for muzakki.
A professional development program with an assessed ePortfolio: A practical solution for engaging undergraduates with their career development in large student cohorts
Authors: Choate Julia , Demaria Maria , Etheve Michelle , Cran Sandy , Carroll David
Published: July 2019

Undergraduate biomedical science degree-programs are considered to be non-vocational, with a diverse range of career outcomes. At our university, student and academic feedback indicated that biomedical science students were anxious and uncertain about their career options. In response to this careers anxiety, an in-curriculum, course-wide and assessed professional development program (PDP) was developed and delivered into the biomedical science degree-program by an integrated team of careers educators and biomedical academics. This program aimed to engage a large cohort of biomedical students (>1000) with their career development, improving their careers awareness and reducing their anxiety about careers options. The impacts of the program on students’ career and employability skills development, as well as their self-reported levels of psychological distress, were evaluated with on-line anonymous student surveys. Student engagement with the program was linked with program assessment submission rates and student interactions with the University Careers Service. Completion of the program increased students’ careers knowledge and confidence, enhanced their awareness of career options and employability skills and increased their engagement with the University Careers Service. It did not alter students’ self-reported levels of depression, anxiety and stress, but students who rated themselves poorly on careers awareness and confidence statements were more likely to have severe depression, anxiety and stress. This program provides a practical approach for students’ career and employability skills development in large cohorts, but could be expanded to include an intervention to reduce student anxiety.
As ficções de fã e o Ensino de Línguas por Tarefas
Authors: Garcia William Danilo
Published: July 2019

Este artigo objetiva discutir os benefícios de se usar a literatura em aulas de inglês e fornecer um plano de aula com foco na produção escrita como forma de evidenciar essa discussão. Assim, as ficções de fã e o Ensino de Línguas por Tarefas foram utilizados como elementos chave no desenvolvimento dessa aula. Sobre a metodologia, este artigo descreve o Ensino de Línguas por Tarefas, o universo literário das ficções de fã e, finalmente, esse plano de aula cujo objetivo é a produção escrita de uma ficção de fã. Referente à abordagem metodológica que embasa essa aula, destacam-se Prabhu (1987), Skehan (1996), Willis, (1996), Nunan (2004) e Ellis (2006), a respeito do Ensino de Línguas por Tarefas; Jenkins (2012) e Neves (2014), que discorrem sobre as ficções de fã, e Dalvi (2012) sobre os usos e benefícios da literatura em uma aula de línguas. Em relação aos resultados, uma atividade respaldada pelos padrões do Ensino de Línguas por Tarefa foi estabelecida de acordo com os seguintes estágios: alunos foram expostos à literatura dos fãs durante a Pré-Tarefa e, então, dada a oportunidade de redigirem suas próprias ficções de fã, que constituiu a fase da Tarefa. Por fim, por meio dessa atividade, foi possível evidenciar que os alunos puderam usar a língua de forma mais autêntica e significativa.
A função de marcador aspectual de sintagmas adverbiais nas construções participiais absolutas licenciadas em textos de autores portugueses dos séculos XV, XVI e XVII
Authors: Gibrail Alba Verona
Published: July 2019

As construções participiais absolutas formadas em textos de autores portugueses nascidos nos séculos XV, XVI e XVII apresentam sintagmas adverbiais definidos na literatura como advérbios de VP em posição mais alta na estrutura dessas orações. A interpretação de tópico do argumento verbal é o fator empírico que define a adjunção desses advérbios a categorias funcionais projetadas acima de VP, funcionando nessas construções como um marcador aspectual.
Interfaces no processo de mediação em teletandem português e espanhol: o papel dos mediadores
Authors: Carvalho Kelly Cristiane Henschel Pobbe de , Ramos Karin Adriane Henschel Pobbe
Published: July 2019

A prática de teletandem em contexto de línguas próximas, como o português e o espanhol, traz algumas especificidades que são inerentes ao processo, tais como, a possibilidade de intercomunicação entre os interagentes. Nesse caso, é necessário observar mais atentamente o papel do mediador na supervisão e acompanhamento de tais interações, de maneira a considerar a relevância dos aspectos linguísticos e culturais. Essa observação pode ser feita por meio de monitoramento constante dos estudantes pelo mediador, como um modo de estimular a conscientização linguística e intercultural. Neste trabalho, temos como objetivo descrever as ações decorrentes desse processo de mediação compreendido de forma mais ampla – que inclui desde os primeiros contatos com as instituições estrangeiras à organização, acompanhamento, supervisão e avaliação –, bem como discutir alguns pressupostos teóricos que podem servir de subsídio ao aprimoramento dessa prática, a partir da perspectiva metodológica da teoria fundamentada (CHARMAZ, 2009). Apresentamos algumas estratégias para esse processo, a partir de nossa experiência na mediação em interações de teletandem português e espanhol, em uma parceria entre uma universidade brasileira e uma universidade mexicana. Nossas análises demonstram que os princípios de autonomia e de reciprocidade (TELLES; VASSALO, 2006) da aprendizagem em tandem estão diretamente relacionados com o processo de mediação e contribuem para a constituição de um contexto profícuo de ensino e aprendizagem de línguas.
Diário escrito para a posteridade: os diários de Getúlio Vargas
Authors: Fernandes Nathalia Reis
Published: July 2019

Ainda que tenha inicialmente mantido seu material em segredo, o autor de um diário pode deixar marcas sutis de seu intuito, que permitem descortinar um desejo velado de exposição. Isso pode se manifestar na atenção ao suporte material em que escreve, no traçado dos caracteres ou outros elementos de fundo codicológico que compõem o material. Nesse sentido, com base em tese de doutorado que abordou, entre outras questões, a caracterização do gênero discursivo “diário”, e com inspiração no documentário Imagens do Estado Novo 1937-45, de Eduardo Escorel (2016), procuraremos analisar se tais características estariam presentes no diário de Getúlio Vargas, escrito entre 1930 e 1942, material em que se pode notar uma variação nos elementos codicológicos ao longo do tempo. Compararemos essas escolhas do autor com os padrões de outros diários, a fim de sustentar nossas conclusões.
Letramento crítico e ensino de espanhol como língua estrangeira: questões teórico-metodológicas no contexto dos Institutos Federais (IFs)
Authors: Benedini Larissa Cristina Arruda de Oliveira
Published: July 2019

O letramento crítico tem sido apontado nos documentos que orientam a educação brasileira de nível médio como uma perspectiva de ensino de língua estrangeira. A formação do leitor crítico também tem sido um critério de seleção das obras aprovadas pelo Programa Nacional do Livro Didático (PNLD). Nesse contexto, são nossos objetivos problematizar o conceito de letramento e leitor crítico que emerge dos documentos e dos livros didáticos, assim como a concepção de leitor crítico e letramento crítico dos professores de espanhol dos IFs. Para isso, aplicamos um questionário com vistas a obter dados sobre a concepção de leitor crítico e letramento críticos dos docentes, a fim de analisar se eles se apropriam das concepções expostas nos documentos e nos livros didáticos em suas práticas de ensino. Os resultados alcançados com as análises apontam a necessidade de maior esclarecimento quanto ao conceito de letramento crítico entre os docentes.
A polêmica sobre a imigração no Brasil: questões de memória discursiva
Authors: Aquino Patrícia Aparecida de , Bitencourt Daiane Rodrigues de Oliveira
Published: July 2019

O objetivo deste artigo é analisar aspectos da polêmica sobre a imigração em diferentes momentos da história brasileira. Para tanto, o artigo fundamenta-se na perspectiva teórica da Análise do Discurso, mais especificamente, nas noções de memória discursiva (COURTINE, 1999), estereótipos (AMOSSY; PIERROT, 2001) e Semântica Global (MAINGUENEAU, 2005 [1984]). O corpus é constituído de enunciados que discutem a imigração em duas épocas diferentes: o século XIX e o século XXI. Os resultados mostram um percurso de memória em que posições são apagadas e retomadas a depender de interesses econômicos e políticos ao longo da história. Estas análises indicam que os enunciadores, ao mesmo tempo que defendem uma posição em relação a alguns grupos de imigrantes como ameaças para o Brasil, constroem uma imagem de si como cordiais, defendendo que não são preconceituosos e racistas.
Integrative analysis of microRNA and mRNA expression in response to salt stress by UMI
Authors: Zhan Jing jing , Diao Yang yang , Zhao Yan yan , Li Chao , Han Xiao , Huang Long yu , sajjad muhammad , Wang Peng , Liu Li sen , Yan Qing di , Wei Xi , Ding Yan peng , Chu Yu , Ge xiao yang
Published: July 2019

Background

Small RNAs play an important role in regulating plant responses to abiotic stress through modulation of the processing, stability, and translation of larger RNAs. Plants employ complex mechanisms of gene regulation to respond to salinity stress.

Results

In this study, we constructed 12 small RNA libraries, 12 mRNA libraries, and a degradome library to systematically investigate the miRNAs response to salt stress. A total of 312 cotton miRNAs were identiﬁed and of these, 80 were known ghr-miRNAs. 144 genes showed significant differential expression under salt stress combined with the targeting relationship between the sRNA data and mRNA data. We found 56 miRNA-mRNA pairs which were positively correlated, and 91 pairs which were negatively correlated. Using degradome sequencing, 72 target genes were identified associated with 25 miRNA families. Gene ontology and KEGG analysis indicated some targets were involved in vital biological pathways of salinity stress tolerance: 14 were involved in responses to abiotic stress, two were associated with an environmental adaptation pathway, and a total of 16 NAC and MYB family transcription factors were related to salinity stress.

Conclusions

The present study identified a large number of cotton miRNAs and identified relationships between miRNA and mRNA, with function annotation revealing their possible biological roles in response to salt stress. Our findings will further functional studies of cotton miRNAs and the salt tolerance mechanism.
Efficacy of urination in alleviating urethral pain associated with flexible cystoscopy - a single-center randomized trial
Authors: Xie Yingwei , Wang Wei , Yan Wei , Liu Dan , Liu Yuexin
Published: July 2019

Objective: This study aimed to assess whether urethral pain can be alleviated by urination in male patients undergoing flexible cystoscopy.
Patient and Methods: Ninety-six male outpatients undergoing flexible cystoscopy were randomly divided into two groups. Patients in the test group urinated during flexible cystoscopy, whilst patients in the control group received no instructions to do so. All patients received 10mL of 2% lidocaine gel prior to assessment. Using 0 (no-pain) to 10 (unbearable severe pain) pain scores (VAS), we assessed patient discomfort prior to anesthesia gel perfusion (baseline), during gel perfusion, during cystoscope insertion through the urethra, and 15minutes post-examination analysis. The entire protocol was completed by a single doctor in our Department of Urology.
Results: The groups showed no statistical differences regarding age or examination time. During cystoscope insertion, the test group recorded significantly lower pain scores 2 (IQR 1-3) - compared to the control group 3 (IQR 2-3) , (P = 0.001). No significant differences between other evaluation points were observed between groups.
Conclusion: Urethral pain can be significantly alleviated by urination in male patients undergoing flexible cystoscopy through the urethra.
SUGAMMADEX ALWAYS FAST? PROBABLY YES, BUT IN LIVER TRANSPLANTATION
Authors: DEANA CRISTIAN , Barbariol Federico , D’Incà’ Stefano , Pompei Livia , Rocca Giorgio Della
Published: July 2019

Background: Rapid neuromuscular block reversal at the end of major abdominal surgery is recommended to avoid postoperative residual. To date, no study has evaluated sugammadex use and performance after rocuronium administration in patients undergoing liver transplantation. This is a randomized controlled trial with the primary objective of assessing the recovery time of neuromuscular transmission with sugammadex versus neostigmine after rocuronium administration in patients undergoing LTx. Methods The TOF-Watch SX® with calibration and linked to a portable computer with TOF-Watch SX Monitor Software® was used to monitor and record intraoperative neuromuscular block, maintained with a continuous infusion of rocuronium. Anaesthetic management was standardized as per our institution's internal protocol. At the end of surgery, neuromuscular moderate block reversal was obtained after administration of 2 mg/kg of sugammadex or 50 mcg/kg of neostigmine (plus 10 mcg/kg of atropine). Results: Data from 41 patients undergoing liver transplantation were analysed. In this population, neuromuscular block recovery time was faster after administration of sugammadex than neostigmine, with a mean value±SD of 9.4±4.6 min vs. 34.6±24.9 min respectively (p<0.0001).Conclusion: neuromuscular block reversal after rocuronium continuous infusion was significantly faster with sugammadex than neostigmine and feasible in patients undergoing liver transplantation. It is important to note that sugammadex recovery time in this population was found to be considerably longer than in other surgical settings, an interesting finding that needs further studies to be fully explained and it should be taken into consideration in clinical practice.Trial registration: ClinicalTrials.gov NCT02697929.Keywords: rocuronium, neostigmine, reversal, recovery time, liver transplantation.
Addition of haloperidol to ondansetron and dexamethasone to prevent postoperative nausea and vomiting in female smoking patients following laparoscopic surgery: A prospective, randomized, double-blind study
Authors: Zhuang Xin-qi , Yang Ji , Zhao Sen , Lu Yue-chun , Xie Ke-liang , Yu Yong-hao
Published: July 2019

Background

Postoperative nausea and vomiting (PONV) is an unpleasant experience that impacts on patient comfort and satisfaction and may lead to other complications. Some risk factors such as female gender and non-smoking status were used to predict the risk of PONV. Regarding its prevention, the combination of two different types of prophylaxis has been demonstrated to exert an additive effect. The present study aimed to evaluate the efficacy of a triple combination of haloperidol, ondansetron and dexamethasone for the prevention of PONV following laparoscopic gynecological surgery in female smoking patients.

Methods

A total of 210 eligible consecutive female patients ranked as American Society of Anesthesiology physical status I-II and aged 18-60 years who were undergoing selective laparoscopic gynecological surgery were included in the current study and allocated into three groups: Patients in group O received 4 mg ondansetron, group OD received 4 mg ondansetron and 8 mg dexamethasone, group ODH received 4 mg ondansetron, 8 mg dexamethasone and 2 mg haloperidol intravenously prior to anesthesia induction. The incidence of PONV, the need for rescue antiemetics, pain score, patient-controlled analgesia (PCA) consumption, rescue analgesics and adverse events were recorded 48 h after operation.

Results

The final analysis consisted of 193 patients who completed the study. Results indicated that the incidence of PONV was significantly decreased in groups OD (20.00%) and ODH (15.63%) compared with in group O (42.19%; P = 0.005). Furthermore, the need for rescue antiemetics was significantly lower in groups OD (13.85%) and ODH (12.50%) than in group O (32.81%; P = 0.005). There was no significant difference in the incidence of PONV or the need for rescue antiemetics between groups OD and ODH (P = 0.516 and 0.821 respectively). No statistically significant differences were detected in pain score, PCA consumption, rescue analgesics or adverse events among the groups (all P > 0.05).

Conclusion

The addition of haloperidol to a combination of ondansetron and dexamethasone did not decrease PONV frequency below that obtained with the two-drug combination. As for female smokers, prophylaxis comprising ondansetron and dexamethasone, with or without haloperidol, could effectively reduce PONV following laparoscopic surgery.
Comparison Efficacy of Bacterial and Fungal Probiotics on Acute Pediatric Diarrhea A Randomized Clinical Trial
Authors: Sharif Alireza , Ardakani Abbas Taghavi , Kashani Hamed Haddad , Rabiee Fatemeh , Sharif Mohammad Reza
Published: July 2019

Background

Diarrheal disease is one of the leading causes of mortality and morbidity in developing countries. Probiotics, recognized as living microorganisms, are known to balance human intestinal flora. Many studies have shown that probiotics can be used as an alternative treatment to acute diarrhea. This study was designed to evaluate the effects of fungal and bacterial probiotics on acute pediatric diarrhea.

Methods

This clinical trial was conducted on 90 children aged 2 to 5 years, who were referred to the Kashan Children's Hospital, Iran, in 2015 for complaints of acute watery diarrhea and were treated on an outpatient basis. These children were randomly divided into three groups of 30. The first group received a standard daily treatment with ORS plus bacterial probiotics as a Kidilact® sachet containing 7 strains of Lactobacillus strains; the second group received ORS and fungal probiotics containing Saccharomyces boulardii as Ardeypharm Yomogi® capsule, 250 mg once a day and the third group used placebo along with standard oral rehydration therapy. The duration of treatment with probiotics or placebo was 5 days.

Results

The current study showed no significant differences in age, gender, frequency and duration of diarrhea between the three groups before admission. The mean duration of diarrhea from onset of treatment to recovery was 2.80 days in the first group (bacterial probiotics), 3.17 days in the second group (fungal probiotics), and 4.43 days in the third group (placebo). A significant difference was observed in the duration of diarrhea after treatment between the three groups (P ≤ 0.05), so that the best effect was found in reducing the duration of diarrhea in the bacterial probiotic group, and the lowest effect was associated with the placebo group.

Conclusion

The use of probiotics in acute diarrhea in children could be effective in shortening the duration of diarrhea; however, the results of this study indicate that bacterial probiotics may seems to be superior to fungi but statistically does not have significant differences.
Trans-rectal natural orifice specimen extraction (NOSE) during laparoscopic anterior resection: Chinese experience with a novel method
Authors: Zhou Zhu-Qing , Wang Kai-Jing , Du Tao , Gao Wei , Zhu Zhe , Jiang Qixin , Ji Fang , Li Dan , Zhang Yuanyuan , Fu Chuan-Gang
Published: July 2019

Background: To introduce a novel method for double stapling technique in colorectal anastomosis during laparoscopic anterior resection of upper rectal or sigmoid colon cancer with trans-rectal natural orifice specimen extraction (NOSE). Methods: From June 2015 and May 2016, patients with upper-rectal or sigmoid colon cancer who received treatment in Shanghai East Hospital were enrolled. Preoperative and postoperative clinical variables were analyzed and compared between groups. Postoperative pain was analyzed utilizing a visual analog scale (VAS). Postoperative overall survival was analyzed using a K-M curve. Results: A total of 99 colorectal cancer cases were randomly divided into NOSE with novel method group (NOSE, n=48) and conventional laparoscopic group (non-NOSE, n=51). No statistically significant differences in preoperative demographics of the patients as sex, age, body mass index were found among the groups. The NOSE group had the longer operation time, but less blood loss than the non-NOSE group. The NOSE group had no abdominal incision and the lower postoperative VAS score. The time for intestinal function recovery and the length of hospital stay (LOS) was statistically significantly different, with the non-NOSE group having the longer time. The incidence of postoperative complications was lower in NOSE group (5/48, 10.4%) than in the non-NOSE group (8/51, 15.7%), the difference was statistically significant. The K-M survival curve showed no statistically significant difference in the disease free survival rate between the NOSE group and non-NOSE group. Conclusion: NOSE with novel method is safe and feasible to use in patients having colorectal cancer. Compared with traditional laparoscopic surgery, the postoperative complication rates of NOSE surgery were lower with an improved short-term clinical recovery.
Busulfan systemic exposure and its relationship with efficacy and safety in hematopoietic stem cell transplantation in children: A Meta-Analysis
Authors: Feng Xinying , Zhao Libo , Wu Yunjiao , Zhang Jingru , Li Jiapeng , Yang Chang qing , Zhu Guanghua , FAN Duanfang
Published: July 2019

Background

Busulfan (Bu) is a key component of several conditioning regimens used before hematopoietic stem cell transplantation (HSCT). However,the optimum systemic exposure (expressed as the area under the concentration-time curve [AUC]) of Bu for clinical outcome in children is controversial.

Methods

Research on pertinent literature was carried out at PubMed, EMBASE, ClinicalTrials.gov and the Cochrane Library. Observational studies were included, which compared clinical outcomes above and below the area under the concentration-time curve (AUC) cut-off value, which we set as 800, 900, 1000, 1125, 1350, and 1500 µM × min. The primary efficacy outcome was notable in the rate of graft failure. In the safety outcomes, incidents of veno-occlusive disease (VOD) were recorded, as well as other adverse events.

Results

Thirteen studies involving 548 pediatric patients (aged 0.3-18 years) were included. Pooled results showed that, compared with the mean Bu AUC (i.e., the average value of AUC measured multiple times for each patient) of > 900 µM × min, the mean AUC value of <900 µM × min significantly increased the incidence of graft failure (RR=3.049, 95% CI: 1.285-7.234). The incidence of VOD was significantly decreased with the mean AUC <1350 µM × min (RR=0.370, 95% CI: 0.205-0.666) and <1500 µM × min(RR=0.409, 95% CI: 0182-0.920).

Conclusions

In children, Bu the mean AUC of 900 µM × min should be considered the lowest threshold associated with its effective prevention of graft failure, while the mean AUC of >1350 µM × min is associated with increased VOD, particularly for the patients not undergoing VOD prophylaxis therapy.
Organizational issues of glaucoma diagnosis in Kazakhstan
Authors: Aldasheva Neilya , Tashtitova Lyailya , Kulmaganbetov Mukhit
Published: July 2019

Purpose

Analysis of the organizational issues of the diagnosis of glaucoma in Kazakhstan and State programs for health care system: “Salamatty Kazakhstan” and “Densaulyk”.

Methods

The state of screening for glaucoma was included increased intraocular pressure (IOP) measurement and pachymetry, which was used for the corneal thickness examination. Although the IOP can be increased or be in the normal ranges, thin central cornea thickness generally was ignored by ophthalmologists. In this regard, the indications for examination for glaucoma with systemic hypotension during screening were expanded, and pachymetry was one of the essential diagnostic tool in the clinical guideline for the diagnosis and treatment of glaucoma as a mandatory research method.

Results

Sufficiency and effectiveness of the screening program was confirmed by the trend in the number of identified patients with glaucoma depending on age. Correlation between suspected glaucoma and age groups was exposed.

The number of registered glaucoma patients was 43,337 patients in 2010. In contrast, after the screening program the figures raised to 68,195 people in 2016. Moreover, there was the increase of newly identified glaucoma cases by 49%: from 70.8 per 100 thousand populations in 2010 to 124 per 100 thousand populations in 2016.

Conclusions

State programs for health care system development in Republic of Kazakhstan "Salamatty Kazakhstan" (2011-2015) and "Densaulyk" (2016 – 2019) were the initial steps for the prevention of the irreversible blindness and disability due to glaucoma. Screening programs allow to timely and adequate diagnosis of the disease over 40 years of age.
Risk factors for periprosthetic joint infection after total knee arthroplasty in Spanish population
Authors: Melchor Francisco , Pescador David , Mendoza Jose , Diaz Agustin , Soler Agustin , Blanco Juan
Published: July 2019

Background: Periprosthetic joint infection (PJI) is the most serious and feared complication in total knee arthroplasty (TKA) and can have catastrophic consequences. The number of total knee arthroplasties has increased and will continue to increase so that the number of infections will also be greater in the future. The aim of this study is to identify the most relevant risk factors associated with infection after a total knee prosthesis in a Spanish population.
Methods: This is a case-control study of patients who underwent total knee arthroplasty at the University Hospital of Salamanca during the period January 1 2010 until January 1, 2015. TKA PJI was detected in 66 patients. As controls, a similar number of patients from the same period who did not develop a periprosthetic infection were included. Demographic and clinical variables were collected. A descriptive and inferential analysis was performed.
Results: Diabetes, ASA grade, obesity and the use or not of antibiotic loaded cement were statistically significant related to the appearance of the infection. For the variables of surgical time and ischemia time, this relationship disappeared when the logistic regression was made.
Conclusions: Our study provides evidence that diabetes, cement type, ASA and BMI were independently associated with increased risk of PJI for TKA patients in a Spanish population. We think that modifiable risk factors were specifically relevant and for that reason we can reduce the infection rate.
Differentiation of mediastinal metastatic lymph nodes in NSCLC based on radiomic features of different phase CT imaging
Authors: Sha Xue , Gong Guan Zhong , Qiu Qing Tao , Duan Jing Hao , Li Deng Wang , Yin Yong
Published: July 2019

Background To develop radiomic models based on different phases of computed tomography (CT) imaging and investigate the efficacy of models to diagnose mediastinal metastatic lymph nodes in non-small cell lung cancer (NSCLC).Methods We selected 231 mediastinal lymph nodes confirmed by pathology results as the subjects, which were divided into training (n=163) and validation cohorts (n=68). The regions of interest (ROIs) were delineated on CT scans of the plain phase, arterial phase and venous phase, respectively. Radiomic features were extracted from the CT images of each phase. Least absolute shrinkage and selection operator (LASSO) was used to select features, and multivariate logistic regression analysis was used to build models. We constructed six models (orders of 1-6) based on radiomic features of the single- and dual-phase CT images. The performance of the radiomic model was evaluated by the area under the receiver operating characteristic curve (AUC), sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV).Results A total of 846 features were extracted from each ROI, and 10, 9, 5, 2, 2, and 9 features were chosen to develop models 1-6. All of the models showed superior differentiation, with AUCs greater than 0.8. The plain CT radiomic model, model 1, yielded the highest AUC, specificity, accuracy and PPV, which were 0.926 VS 0.925, 0.860 VS 0.769, 0.871 VS 0.882 and 0.906 VS 0.870 in the training and validation sets, respectively. When the plain and venous phase CT radiomic features were combined with the arterial phase CT images, the sensitivity increased from 0.879, 0.919 to 0.949, 0979 and the NPV increased from 0.821, 0.789 to 0.878, 0.900 in the training group, respectively.Conclusion CT radiomic models based on different phases all showed high accuracy and precision in the diagnosis of LNM in NSCLC patients. When combined with arterial phase CT, the sensitivity and NPV of the model can be further improved.