bluuebunny/crossref_metadata_2025 huggingface dataset:
SMI-32 — a novel axonal injury marker for investigation of ischemic brain pathology
Authors: Tsyba Daria L. , Kirik Olga V. , Korzhevskii Dmitrii E.
Published: April 2021

The relevance of this work is determined by the high prevalence and social significance of cerebrovascular diseases and the need to develop effective methods for verifying neuronal damage due to cerebral ischemia in experimental models.
The aim of this study was to assess the possibility of immunohistochemical revealing of neurofilaments to detect axonal injury in cerebral ischemia models.
Materials and methods. A model of transient focal cerebral ischemia by the left middle cerebral artery occlusion was reproduced in male Wistar, SHR and WKY rats. Axonal injury was assessed by immunohistochemical reactions for neurofilament proteins using SMI-32 and 2F11 antibodies.
Results. In cerebral ischemia, damage to nerve fibers occurs, manifested by thickening of axons, their varicose expansion and segmental accumulation of neurofilament proteins. These changes are more noticeable with an immunohistochemical reaction to the SMI-32 marker of neurofilament heavy chain.
Conclusions. The use of antibodies to the non-phosphorylated neurofilament heavy chain makes it easy to identify degenerating nerve fibers and can be recommended as an alternative method for detecting axonal injury.
The role of hypoxia in the integrity of the genetic apparatus and the formation of memory in drosophila in the paradigm of conditioned reflex suppression of courtship
Authors: Medvedeva Anna V. , Tokmacheva Elena V. , Nikitina Ekaterina A. , Vasilieva Svetlana Alexandrovna , Zalomaeva Ekaterina S. , Savvateeva-Popova Elena V.
Published: April 2021

M.E. Lobashev and V.В. Savvateev in 1959 obtained unique data on the expansion of the adaptive capabilities of the organism when training the properties of higher nervous activity by the formation of conditioned food reflexes to stimuli that exhaust the nervous system. Apparently, the formation of a conditioned connection help to overcoming stressful effects, adaptation to restrictive conditions, and changes in the functioning of the nervous system. To test this assumption, the influence of stressful influences hypoxia on learning and memory of Drosophila in the paradigm of conditioned reflex suppression of courtship was studied. The results were obtained on the enhancement of the ability to learn under hypoxic exposure. These experimental conditions did not affect memory formation. The effect of hypoxia on chromosomes through the formation of double-stranded breaks was revealed. The data are discussed in light of the relationship between neuroplasticity processes and mechanisms of adaptation to stressors.
Evaluation of plasma levels of meropenem in septic patients during extracorporeal blood purification
Authors: Marukhov Artem V. , Murzina Elena V. , Zakharov Mikhail V. , Sofronov Genrikh A. , Buryakova Lyudmila V. , Ivanov Maxim B. , Zhurkovich Inna K. , Ostrovidova Ekaterina V.
Published: April 2021

The relevance. Meropenem is a broad-spectrum carbapenem antibiotic widely used to treat patients with sepsis / septic shock. Critically ill patients are usually supported with one of the forms extracorporeal blood purification. However, data on the effect of various extracorporeal support techniques on the pharmacokinetics and pharmacodynamics of meropenem are insufficient or contradictory.
Aim: To evaluate the effectiveness of meropenem dosage regimens in the treatment of septic patients during extracorporeal blood purification.
Materials and methods. Plasma concentrations of meropenem were monitored in three critically ill patients with sepsis or septic shock. Patients were treated using various extracorporeal support techniques. Meropenem was used as empirical antibacterial mono- or complex therapy (1 g every 8 or 12 hours). Meropenem concentrations in plasma were determined by validated assay methods on Acquity ultraefficient liquid chromatography (UPLC) H-Class system.
Results. It is shown that the meropenem plasma concentration in critically ill patients changes significantly. It was found that the standard meropenem dosing regimens in patients with sepsis / septic shock during continuous hemodiafiltration do not ensure the achievement of the PK/PD target of 100% TMIC for sensitive strains (MIC2 mg/L) and for intermediate resistance pathogens (2MIC8 mg/L). Continuous hemofiltration and selective adsorption of lipopolysaccharide have a less pronounced effect on the clearance of meropenem.
Conclusion. To increase the effectiveness of antibacterial therapy, it is necessary to conduct research aimed at developing protocols for dosing antibacterial drugs for the treatment of sepsis during extracorporeal blood purification.
The peculiarities of pulmonary macro- and microhemodynamics changes after treatment with agonists and blockers of cholinoceptors
Authors: Evlakhov Vadim I. , Poyassov Ilya Z. , Berezina Tatiana P.
Published: April 2021

Background. The pulmonary arterial and venous vessels are innervated by parasympathetic cholinergic nerves. However, the studies, performed on the isolated rings of pulmonary vessels, can not give answer to the question about the role of cholinergic mechanisms in the changes of pulmonary circulation in full measure.
Aim. The comparative analysis of the changes of the pulmonary macro- and microhemodynamics after acetylcholine, atropine, pentamine and nitroglycerine treatment.
Materials and methods. The study was carried out on the anesthetized rabbits in the condition of intact circulation with the measurement of the pulmonary artery pressure and flow, venae cavae flows, cardiac output, and also on isolated perfused lungs in situ with stabilized pulmonary flow with measurement of the perfused pulmonary artery pressure, capillary hydrostatic pressure, capillary filtration coefficient and calculation of the pulmonary vascular resistance, pre- and postcapillary resistances.
Results. In the conditions of intact circulation after acetylcholine, pentamine and nitroglycerine treatment the pulmonary artery pressure and flow decreased, the pulmonary vascular resistance did not change as a result of decreasing of pulmonary artery flow and left atrial pressure due to diminution of venous return and venae cavaе flows. On perfused isolated lungs acetylcholine caused the increasing of pulmonary artery pressure, capillary hydrostatic pressure, pulmonary vascular resistance, pre- and postcapillary resistance and capillary filtration coefficient. After M-blocker atropine treatment the indicated above parameters of pulmonary microcirculation increased, on the contrary, after N-blocker pentamine treatment they decreased. Nitroglycerine infusion caused less decreasing of the parameters of pulmonary microcirculation in comparison with effects of pentamine, but capillary filtration coefficient decreased to a greater extent. These data indicate that nitroglycerine decreases endothelial permeability of pulmonary microvessels.
Conclusion. After activation or blockade of cholinergic mechanisms in the condition of intact circulation the calculated parameter of pulmonary vascular resistance is depended from the ratio of the pulmonary artery pressure and flow and left atrial pressure, which are determined by the venous return. The different character of the changes of pulmonary microcirculatory parameters after M-blocker atropine and N-blocker pentamine treatment is evidence of reciprocal relations of M- and N-cholinoceptors in the nervous regulation of the pulmonary microcirculatory bed.
Pathophysiological and age-specific mechanisms of morpho-functional changes in spermatozoa in infertility
Authors: Dotsenko Anna A. , Polevshchikov Alexander V.
Published: April 2021

The aim of the review is to analyze the causes and pathophysiological mechanisms of sperm alteration accompanying the development of male infertility, the sequence of the development of their dysfunctions in individuals of different ages. Male infertility is a worldwide problem; up to 20% of married couples are childless. In the Russian Federation, the problem is even more acute, which complicates the unfavorable demographic situation. Based on the generalization of the results of various screening studies, from 30 to 50% of men in the Russian Federation have impaired fertility. The review examines the main classifications and pathophysiological mechanisms of the development of male infertility. An extended assessment of changes in the morphology and functional properties of spermatozoa, relevant for the practice of in vitro fertilization, was carried out. The mechanisms of damage to spermatozoa and the sequence of development of degenerative changes in the cell are considered in detail. The mechanisms of sperm dysfunction development in men of different ages are compared. The conclusion is made about the need for further studies of the molecular mechanisms of fertility, deciphering the entire set of interactions between molecules and cells involved in the implementation of the reproduction function.
Yellow Pumpkin (Cucurbita maxima D.) Extract As Anti-Hypercolesterolemia
Authors: Sunnah Istianatus , Kustiyaningsih Erna , Oktianti Dian
Published: April 2021

Hyperlipidemia is a risk factor for various diseases, which is still a big problem in Indonesia. Yellow pumpkin (Cucurbita maxima D.) is a plant containing flavonoids and terpenoids, which can be used as an anti-hypercholesterolemic agent. This study aims to analyze the activity and dosage of yellow pumpkin extract, which can be used as an anti-hypercholesterolemic agent to reduce total cholesterol levels comparable to simvastatin by 1.8mg/kg BW/day. This research is pure experimental research with a pre and post-test group design approach. The number of samples was 25 male Wistar rats induced by high-fat feed, quail egg yolk: pork oil (2:1) by 5 ml/200 gramBW/day for 7 days. The extract dosage range was 200, 400, 600 mg/kg BW/ day  for 7 days. Data were analyzed using One Way ANOVA. The results showed that the administration of yellow pumpkin extract could reduce rats' total blood cholesterol levels with a dose of 600 mg/kg BW/day, comparable to simvastatin 1.8 mg/kg BW/day. The secondary metabolites of the extract were flavonoids and terpenoids. Extract of yellow pumpkin (Cucurbita maxima D.) could reduce total blood cholesterol levels of rats. The dose of 600 mg/kg BW/day could reduce blood cholesterol levels in rats comparable to simvastatin 1.8 mg/kg BW / day.
Comparison of three different techniques for internal jugular vein cannulation under real time ultrasound guidance
Authors: Mahajan Reena , Malhotra Suchitra
Published: April 2021

Background: Ultrasound (USG) guided Internal jugular venous (IJV) cannulation is preferred than traditional approach due to increase in success rate, reduction in time taken and attempts of successful cannulation and less complications. The purpose of our study was to observe and compare three different real time 2-dimensional US-guided approaches and to determine which approach improves rate of successful cannulation, decreases complications along with shorter average time taken for the procedure. Primary outcomes of the study were venous access time, catheterization time and success rate. Secondary outcomes were number of patients requiring second attempt and complications observed.

Methods: 120 adult patients were randomly divided into three groups according to real time US guided cannulation done with SAX-OP approach, LAX-IP approach and OAX-IP approach. Parameters like venous access time, catheterization time, number of patients requiring second attempt and complications were noted.

Results: Venous access time was shortest in LAX group 21.84±3.67 seconds which was just significant statistically. Catheterization time was shortest in LAX group 241±123 seconds. Cannulation success rate was highest in LAX group 98% and was statistically significant. Patients requiring second attempt was least in LAX group 2.5%. Posterior IJV wall puncture was observed in 10% patients in SAX group and none in LAX and OAX group which was statistically significant.

Conclusions: LAX-IP showed better performance in terms of higher cannulation success, lesser average venous access time and catheterization time and lesser complications. On toggling USG probe, both IJV and carotid artery can be differentiated and carotid puncture could be avoided. Hence LAX approach is safer and effective approach.
A study of serum C peptide levels in newly detected diabetic patients in tertiary care hospital
Authors: Teli Balakrishna , S. Prabhu , Biradar Sneha
Published: April 2021

Background: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. The deficiency of C-peptide in type 1 DM or its excess in type 2 DM leads to the development of disorders which includes the cardiovascular, nervous, excretory and other systems. The present study is done to assess the serum C-peptide levels in newly detected diabetic patients and its significance in classification of diabetes and deciding about management.Methods: This cross sectional study was conducted within the hospitals attached to Bangalore medical college and research institute. 65 newly detected diabetes patients who gave consent for study and satisfy the inclusion criteria were included in the study. Data was collected using semi structured questionnaire, clinical examination and relevant investigations. Statistical analysis was performed using SPSS software. A p value of <0.05 was considered significant.Results: C-peptide levels showed that 34 (52.3%) subjects had C-peptide levels >2 followed by 10 (15.4%) subjects having 0.1 to 0.6, 9 (13.8%) subjects having 1 to 2, 6 (9.2%) subjects each having 0.6 to 1 and <0.1.Conclusions: Serum C-peptide levels are useful as an index of endogenous insulin production. Low C-peptide levels need insulin treatment due to poor insulin reserve. Majority of the subjects, who had low serum C-peptide levels also had low BMI suggesting a positive correlation between C-peptide levels and BMI.
Test dosing as an alternative treatment approach in urinary tract infection patient with Cefoperazone allergy
Authors: Komara I. Made Adi Narendranatha , Suryana Ketut
Published: April 2021

Drug hypersensitivity reaction (DHR) is classified as adverse reaction which is based on immunologic mediated reaction. Antibiotics are the most frequently prescribed drugs given to patients to treat bacterial infections, but also cause adverse drug reactions due to hypersensitivity in patients. We present here a case of cefoperazone drug allergy in a 75 years old patient with urinary tract infection requiring the test dosing approach.
Pattern of skin diseases among patients attending Hawassa university comprehensive specialized hospital, Hawassa, Ethiopia
Authors: Assefa Girum T. , Koster Adane C. , Nurhussein Nura K.
Published: April 2021

Background: Spectrum of skin diseases varies from region to region due to several factors such as genetics, socioeconomic and environmental. This study aimed to determine the pattern of various skin disorders appearing in the dermatology department of a tertiary care hospital.

Methods: All patients attending the dermatology clinic of the Hawassa university comprehensive specialized hospital, from January 2017 to December 2018 were included in this retrospective analysis. The medical records of the patients were obtained from registry books. 

Results: A total of 7727 patients attended the dermatology clinic of HUCSH. Out of these samples, 18.1% of patients repeatedly came to the hospital for a follow up visit related to their diseases, while 81.9% were enrolled as new cases.

There were more males (51.9%) than females. More than three quarter of the cases were aged above 16 years while less than a quarter were children below 16 years. Eczema was diagnose in 2734 (35.4%), being the most common cause for attendance, followed by infectious disease (23.3%) and disease of the skin appendages (12.1%).

Conclusions: Eczema was the most common skin disease seen in our study, followed by infectious disease   and disease of the skin appendages. Concerted effort need to be made to control these conditions and training of the primary health care providers and education of General Practitioners in Dermatology must emphasize these common conditions, with the aim of improving primary health care and alleviating the burden of hospital care.
Disaster of housing care amenities versus COVID-19 in urbanized countries: medication of social science
Authors: Ali Anwar , Ahmed Munir , Bostani Ahmed , Ain Qurat U. , Saeed Ayesha
Published: April 2021

In the background of the COVID-19 epidemic, a big portion of developed nations have suffered an exceptionally high human death toll residing in nursing care homes. In order to further explain this process, public epidemiology contributes significantly, due to the biological influence of the pathogen on as a core feature of wellbeing, disadvantaged high-risk communities and to the position of treatment. The catastrophe of deaths associated with COVID-19 in care centers is largely attributed towards its iatrogenic distribution and exacerbated by societal factors. Present segregation and containment measures have struggled to illustrate their efficacy in mitigating these trends, along with the extended alienation of tenants from their companions, and are thus excessive. Reforms that value for both protection interests of all citizens and fundamental rights must be substituted. Now about the dubious feasibility, these initiatives carry substantial costs of chances, because as standard of health and life conditions of isolated inhabitants are adversely impacted. The COVID-19 issue, viewed in specific from the prism of pharmacy as a public study and social epidemiology, creates ability to correctly appreciate and radically strengthen system parameters.
Land Suitability and Economic Performance in the Pasuruan Region for Coffee Development
Authors: Nugraha Achmad T. , Prayitno Gunawan , Khoiriyah Lailatul A.
Published: April 2021

The identification of superior commodities is one of the initial stages of the development of the agro-policy area. This study aims to identify the leading agricultural commodities, land suitability, and the Pasuruan Regency's economic performance. Determination of superior commodities using Location Quotient (LQ) analysis, shift-share analysis, land suitability analysis, potency and problem analysis, and final analysis of district government policy. We found that coffee is the most widely produced plantation commodity in Pasuruan Regency. The shift-share analysis shows that coffee and tobacco grow faster than any other commodity. The land suitability analysis shows that coconut, coffee, cane, and tobacco could be planted in all Pasurua Regency areas. The Government should support coffee's economic performance in the provision of seed, training, organization of coffee events, and sale of coffee processing technology. However, several areas need to be addressed, including cooperative enterprises, agricultural terminals, and business certainty. Besides, cooperation with other industries is also needed to develop international markets.
Analysis of the effectiveness of instructional recommendations for forming practical skills and abilities in adolescents
Authors:   Yuri Gagarin State Technical University of Saratov, Gainutdinova Irina R.
Published: April 2021

Lessons for forming practical skills and abilities are significant in the educational process. A laboratory lesson, as the main type of lessons for forming practical skills and abilities, is linked to a number of difficulties in organizing effective work of adolescent schoolchildren. The purpose of the study is to experimentally check the effectiveness of the developed instructional recommendations for forming practical skills and abilities in adolescents, taking into account age and gender role characteristics. The hypothesis of the study is: the developed instructional recommendations increase the effectiveness of development of practical skills and abilities in adolescent schoolchildren. The study substantiates the necessity of using the knowledge of age and gender-role characteristics of schoolchildren by a teacher in organizing and conducting laboratory lessons. The study also highlights the methodological research principles, i.e. individually differentiated and holistic approach to teaching schoolchildren. The study is carried out on a sample of 8th grade students (N = 52, aged from 13 to 14 years; experimental group (n = 25), control group (n = 27)) of the educational institution “Gymnasium No. 1” in Saratov. We carried out inter-group analysis of average grade points of schoolchildren for laboratory works in physics, chemistry and biology during the 2018-2019 academic year using the Mann – Whitney U test. It showed that the developed instructional recommendations contribute to an increase in the effectiveness of the formation of practical skills and abilities in adolescents, while not significantly affecting the average grade points. The applied aspect of the problem under study can be implemented in the development of a complex of pedagogical strategies that ensure the effectiveness of the formation of practical skills and abilities in adolescent schoolchildren during laboratory lessons.
La Convención Internacional sobre los derechos de las personas con discapacidad y las teorías de la justicia: La participación política de las personas con discapacidad
Authors: Heredia Ríos Elkin Andrés , Hurtado Maya Alexandra , Echeverri Herrera Jenny Alexandra
Published: April 2021

Partiendo de los principios sociales de la Convención Internacional de Naciones Unidas sobre los derechos de las personas con discapacidad (2006), se estudia el modelo social de la discapacidad que la inspiró, con el propósito de evaluar los modelos de justicia que pueden llegar a ajustarse a esta transformación en la comprensión de la discapacidad. Paso seguido se analizan las teorías de la justicia más relevantes que se han diseñado en las últimas décadas a partir del criterio de la manera en que abordan el problema de la justicia para las personas con discapacidad. Finalmente, se propone un balance de las teorías expuestas y se toma una posición relacionada con la demanda de participación política que se expresa en la Convención y en el informe sobre su implementación en Colombia en el año 2016.
Deliberative Democracy, Social Rights and the Modulation of Judicial Review
Authors: Valentini Chiara
Published: April 2021

Roberto Gargarella has infused into constitutional theory a deliberative approach to constitutional review and rights adjudication. By this, he has enriched our understanding of deliberative democracy as a political system in which the judiciary can play a central role, especially through the institution of constitutional review. Furthermore, he has provided us with crucial insights into the deliberative potential of this institution, shedding light on the different ways in which it may serve to secure the essential conditions of democratic deliberation. The article centers on this twofold, crucial contribution of Gargarella – to constitutional theory and to deliberative democratic theory – with a focus on the relationship between social rights and constitutional review. First, it presents the main controversial issues raised by this relationship, concerning both social rights justiciability and adjudication. Second it highlights the resources provided by Gargarella to understand and address both orders of issues, based on his account of deliberative democracy and constitutional review. Third, the article addresses the resulting view of the action of courts on social rights. In particular, it inquires into the idea of a “third way” for judicial action, requiring to modulate judicial review so as to mediate between judicial inertia and activism.
Castigo y comunidad: algunas reflexiones en torno al debate Gargarella-Duff
Authors: Fernandez Fiks Tomás
Published: April 2021

El artículo analiza algunos puntos del diálogo entablado en los últimos años entre Roberto Gargarella y Antony Duff. Gargarella ha criticado a Duff por defender una mirada que incorpora elementos de dos concepciones políticas rivales, el liberalismo y el comunitarismo, dando lugar a una teoría que es internamente inconsistente. El problema de dicha crítica es que Gargarella incurre en el mismo tipo de contradicción que atribuye a Duff. Luego de identificar la tensión que está presente en la obra de Gargarella se propone una forma posible de resolverla.
Prenatal stress impairs recognition memory and leads to neurodevelopmental deficits in hippocampus of adolescent rats with early acute pentylenetetrazole-kindling
Authors: ÇELİK Kübra , BİLİM Petek , GARİP Gurur , DURMAZ Burak , Y. SÖZMEN Eser , BAKA Meral
Published: April 2021

Objectives: This study aimed to investigate the effects of prenatal stress (PS) on hippocampus of early acute pentylenetetrazole (PTZ)-kindled offspring in adolescence. Recognition memory, morphological changes and synaptophysin levels in hippocampus were evaluated.
Methods: Restraint stress was induced to a group of pregnant dams and non-stressed (NA) group remained undisturbed. Next, male and female offspring were divided as 1. PS-PTZ, 2. PS -control, 3. NA-PTZ and 4. NA-control (n = 12 in each group). The object recognition test was performed following PTZ injection (45 mg/kg) on postnatal day 10 (P10). Brains were collected on postnatal day 35 (P35) to determine neuronal density and synaptophysin expression by immuno/-histological studies. Further, oxidative stress products in hippocampus were analyzed with different biochemical assays.
Results: PS impaired recognition memory in PTZ group significantly (p = 0.03); however, the impairment of PS was reversible in control group compared to PTZ (p = 0.04). Furthermore, PS caused neuronal loss in CA1 (p = 0.01) and decreased synaptophysin expression in the CA3 area of hippocampus in PTZ group (p = 0.03). PS also increased the oxidative stress markers in PTZ group significantly (p < 0.05).
Conclusions: These results suggest that PS causes neurodevelopmental deficits in adolescent hippocampus and recognition memory after early-life seizures prominently. However, the damage of only PS in adolescence can be reversible. Therefore, the effects of PS in the adult hippocampus and other regions of brain need to be further studied.
The ‘Other’ Here and the ‘Other’ There:
Authors: Currie Mark T. S.
Published: April 2021

Through examining key family narratives and selected personal experiences in this article, I reflect on how I began to rethink and (re)frame the representation of my racialized and (trans)national identities as a hyphenated, South African-Canadian citizen. The article summarizes my experiences of visiting Cape Town, South Africa (for the first time), when I engaged in a semester-long, secondary school teaching internship, conducting in-class action research while teaching Grades 9 and 10 History and English. I was sure that I was not just going to teach—I was going to discover myself. To borrow Derrida’s term, the “edges” of my identity continue to become blurred in relation to the shifting social and economic contexts.
Posthumanism: A Desire for a New Humanity
Authors: Sidebottom Kay , Lee Carol , Fairchild Nikki
Published: April 2021

Call for Submissions for the Summer, 2022 issue of Cultural and Pedagogical Enquiry for the Special Issue: Posthumanism: A Desire for a New Humanity with Guest Editors Kay Sidebottom, Carol Lee, and Nikki Fairchild.
Raport z badania 2016. Specjalne Strefy Ekonomiczne w Polsce w oczach przedsiębiorców i pracowników samorządu
Authors: Pastusiak Radosław , Jasiniak Magdalena , Keller Jakub , Krzeczewski Bartłomiej
Published: April 2021

Niniejszy raport prezentuje wyniki projektu realizowanego w ramach projektu badawczego nr UMO-2013/09/B/HS4/, pt. Efektywność Specjalnych Stref Ekonomicznych, przez zespół Katedry Finansów Korporacji, Wydział Ekonomiczno-Socjologiczny Uniwersytetu Łódzkiego, pod kierownictwem dr hab. Radosława Pastusiaka, prof. nadzw. UŁ. w składzie: dr Magdalena Jasiniak, mgr Jakub Keller, mgr Bartłomiej Krzeczewski. Zasadniczym celem badania było określenie efektywności funkcjonowania Specjalnych Stref Ekonomicznych w Polsce (SSE). SSE poprzez działalność przedsiębiorstw, które ulokowały w nich swoje inwestycje oddziałują na otoczenie społeczne i gospodarcze. Projekt miał za zadanie oszacować ten wpływ na gospodarkę regionalną oraz krajową. W ramach projektu została zbadana rola społeczna i gospodarcza przedsiębiorstw zlokalizowanych na terenie SSE w Polsce.
Kadınların Kişilik Özellikleri ile Psikolojik Sağlamlık Düzeyleri Arasındaki İlişkinin İncelenmesi
Authors: YAZICI ÇELEBİ Gülin
Published: April 2021

Üzerinde uzlaşılmış bir tanımı olmamasına rağmen kişilik yüzyıllardır incelenen bir konudur. Farklı boyutlarda ele alınmakla beraber daha çok kişilik belirli özelliklerin gösterilip gösterilmemesi ile sınıflandırılmaya çalışılmaktadır. Hangi kişilik özelliğinin hangi davranışlara ya da yaşam becerilerine yatkınlık oluşturduğu da ayrıca incelenmeye açık bir konudur. Bu araştırmanın amacı da bireylerin kişilik özellikleri ile psikolojik sağlamlık düzeyleri arasındaki ilişkinin incelenmesidir. İlişkisel tarama modeli kullanılan araştırmanın çalışma grubunu 18 yaş üstü 312 kadın oluşturmaktadır. Araştırmaya katılım gönüllülük esasına göre sağlanmış ve basit örnekleme yöntemi ile 2019 yılında toplanmıştır. Veri toplama araçları için gereken izinler alınmıştır. Veri toplama aracı olarak Türkçe uyarlama çalışmaları Bal ve Şahin (2011) tarafından yapılan Cervantes Kişilik Ölçeği ile Doğan (2015) tarafından Türkçeye uyarlanan Kısa Psikolojik Sağlamlık Ölçeği kullanılmıştır. Ayrıca araştırmacı tarafından hazırlanan kişisel bilgi formu ile çalışma grubuna ilişkin demografik bilgiler toplanmıştır. Elde edilen veriler SPSS 25 programında analiz edilmiştir. Yapılan normallik analizlerinden sonra uygulanacak tekniklere karar verilmiş, değişkenler arasındaki ilişkilerin analizinde Pearson korelasyon tekniği, ikili değişkenlerin karşılaştırılmasında t-testi, üç ve daha fazla kategorili değişkenlerde ise tek yönlü varyans analizi kullanılmıştır. Farkın kaynağını belirlemek için Bonferroni testinden yararlanılmıştır. Yapılan analizler sonucunda psikolojik sağlamlık ile kişilik özellikleri alt boyutları arasında anlamlı ilişkiler olduğu, yaş, medeni durum, eğitim düzeyi, bir işte çalışıp çalışmama durumu açısından da anlamlı farklılıklar olduğu belirlenmiştir. Elde edilen veriler alanyazın ışığında tartışılmıştır.
Necib Mahfuz’un Kahire Üçlemesi’nde Türk İmgeleri
Authors: BRITTEN Fatoş Işıl
Published: April 2021

Nobel ödülünü kazanan ilk Arap yazar olarak bilinen Necib Mahfuz’un Beyne’l-Kasrayn, Kasru’ş-Şevk ve es-Sükkeriye (Saray Gezisi, Şevk Sarayı ve Şeker Sokağı) romanlarından oluşan Kahire Üçlemesinde (1957 ve 1958) Mısırlı tüccar bir ailenin üç kuşağı üzerinden 1917-1944 yılları arası Mısır yaşamı gerçekçilik akımı çerçevesinde anlatılır. Bu yaşamın ayrıntılarında aile yaşantısı, kadın erkek ilişkileri, Mısır’daki siyasi olaylar ile yirminci yüzyılın ilk yarısında ivme kazanan modernleşme süreci vardır. Tüm bu zengin katmanların arasında roman, anlatıcı ve diyaloglar vasıtasıyla o dönemki Mısır halkının zihnindeki Türk imgelerinin sorunsal doğasını yansıtması sebebiyle de dikkat çeker. Çoğunlukla karşılaştırmalı edebiyatın bir alt kolu olarak kabul edilen ya da onunla iç içe geçmiş çalışmalar yapan imgebilim ise kültürlerin diğer kültürler hakkındaki inanış, önyargı ve düşünce kalıplarının dair farkındalık kazandırmayı amaçlayan bir disiplindir. Bu inanış ve önyargılara göre şekillenen imgeler sabit olmayıp siyasi koşullara ve devletlerin birbirleriyle olan ilişkilerine göre zaman içinde değişim göstermektedir. On yedinci yüzyılda Avrupalı gezginlerin doğu seyahatleri ile ortaya çıkan imge çalışmaları Türk imgeleriyle ilgili olarak da zengin bir malzeme sunar. Bu çalışma geçmişten günümüze dünyadaki Türk imgelerini kısaca gözden geçirdikten sonra Kahire Üçlemesi’ni karşılaştırmalı edebiyatın yakın okuma yöntemi ile inceleyecek olup Mısır özelinde on dokuzuncu ve yirminci yüzyılın ilk yarısındaki Türk imgelerini ortaya çıkarmayı hedeflemektedir.
Mengembangkan Moderasi Beragama Mahasantri Melalui Ta’lim Ma’hadi di Pesantren Mahasiswa
Authors: Maskuri Maskuri , Ma'arif A. Samsul , Fanan M. Athoiful
Published: April 2021

The article describes and analyzes ta’lim ma’hadi in al-Hikam Malang Student Islamic Boarding School and the values implemented to develop the moderate character of the mahasantri religion. This study used a qualitative approach with a case study design. The data in this study were taken through interviews, observation, and document techniques. This study indicates that the al-Hikam Malang student boarding school uses three strategies in religious moderation, namely, nurturing patterns, teaching patterns, and religious patterns. The three strategies are integral in the curriculum that is implemented there. Through the applied curriculum, kyai and asatidz as qudwah hasanah internalize the values of justice, balance, harmony, moderation. As well as being a moderate Muslim, the mahasantri al-Hikam graduate is expected to become a successful entrepreneur.
Resiliensi Pesantren Terhadap Ekstrimisme Kekerasan Berbasiskan Agama dan Implikasinya terhadap Masyarakat Pesisir Lamongan
Authors: Muthohirin Nafik , Suherman Suherman
Published: April 2021

Pesantren has a strategy of resilience from the infiltration of the ideology of religious violent extremism. This resilience comes from the kiai's charisma and institutional commitment to the integrity of the country which has implications for the practice of Islamic education in Islamic boarding schools. This article discusses the form of the resilience of the Pesantren Karangasem Muhammadiyah Lamongan from the ideology of religious violent extremism. Pesantren Karangasem is located in Paciran, which borders Brondong, Lamongan, where religious life in the two coastal villages of Lamongan faces serious challenges because it is becoming pockets of movement for Islamic extremist groups. This article poses two thesis questions: First, what is the form of the resilience of the Pesantren Karangasem from the ideology of religious violent extremism; Second, how this form of resilience can have implications for preventing the entry of radical Islamic actors into the religious life of the coastal community of Lamongan. This study concludes that Pesantren Karangasem is an Islamic educational institution that contributes to spreading moderate Islamic views through several forms of resilience that originate from the kiai's charisma and the Islamic intellectual tradition of the pesantren. This study also emphasizes that even though the infiltration of massive religious-based violent extremism movements has occurred, the practice of Islamic cosmopolitan which is the character of religious life in the coastal community of Lamongan is always maintained.
El movimiento estudiantil en la Universidad Pedagógica y Tecnológica de Colombia 1971
Authors: Bernal Villate Sandra Liliana , Patiño Diego Eduardo Naranjo
Published: April 2021

El Objetivo: de este trabajo se centra, en el análisis del movimiento estudiantil de la Universidad Pedagógica y Tecnológica de Colombia, en el año 1971.

Originalidad/aporte: se centraliza, en la movilización y planteamientos de reforma estudiantil por conseguir el cogobierno universitario, que realizaron los grupos políticos de izquierda, en esta institución.

Método: se inscribió en la historia política

Estrategia/recolección de información: se enfocaron en la recuperación de la memoria de sus protagonistas, contrastada con la revisión de las Actas de los consejos académico y superior y las publicaciones de la prensa nacional sobre el tema de las movilizaciones estudiantiles.

Conclusiones: se puede concluir que, en esta universidad, las divisiones internas de los colectivos estudiantiles, junto con las políticas represivas de expulsión y la no vinculación del sector social y sindical a movimiento, incidieron en el hecho de no lograr una negociación local que permitiera alcanzar el sueño del cogobierno universitario, que sólo se lograría en Colombia, hasta el año 1991, con el cambio de la Constitución política del país.
Quantification of Calcium Titanate (CaTiO3 ) by the Rietvield Method in Different Molar Proportions
Authors: Gralik Guilherme
Published: April 2021

O objetivo do presente estudo é produzir titanato de cálcio (CT) com estrutura perovskita (ABO3 ) a partir de rutilo comercial (TiO2 ) e carbonato de cálcio comercial (CaCO3 ). As matérias-primas foram caracterizadas por difração de raios X (DRX). Diferentes composições foram formuladas, as amostras foram comprimidas a 150 MPa e sinterizadas em forno resistivo a temperaturas de 1300 °C por 3h. As amostras foram analisadas por DRX após o processo de sinterização e as fases foram quantificadas de acordo com o método de Rietveld. As imagens foram representadas por meio de microscopia eletrônica de varredura (MEV), a fim de mostrar as características das microestruturas formadas. A densidade dos pellets sinterizados foi medida usando o método de Arquimedes. De acordo com os resultados, a formação do CT depende da razão molar entre os cátions cálcio e titânio nas composições analisadas.
Condensação da Água Atmosférica com Peltier
Authors: Igor T. B. Medeiros  , Matheus S. Oliveira  , Victor E. N. A. Pericoli
Published: April 2021

O trabalho consiste na análise de simulações para obtenção de água do ar atmosférico com uso de módulos peltier e dissipadores, testando a eficiência da temperatura na extensão das aletas e na condensação da água, ambos com influência de ventilação forçada e umidade. Os resultados mostram que sem o uso da ventilação é possível atingir a temperatura do ponto de orvalho até a extremidade das aletas em situações de baixa umidade, com alta umidade tal temperatura atingiu a extremidade tendo ou não o uso da ventilação forçada, porém a fração de água condensada foi prejudicada conforme o aumento da ventilação.
Otimização Paramétrica Veicular Via Algoritmos Genéticos
Authors: Vinícius P. Lemes  , Gino B. Colherinhas
Published: April 2021

Este trabalho apresenta uma aplicação de algoritmos genéticos em um veículo automotivo, para buscar parâmetros ótimos de rotação de motor utilizados nas mudanças de marcha com o objetivo de otimizar a economia de combustível e performance em aceleração de 0 a 100 km/h. Foram considerados os testes de economia de combustível padronizados FTP e HWFET. A otimização buscou três perfis de direção ótimos: uma otimização global, uma otimização específica que desconsidera o teste HWFET e uma que desconsidera o teste FTP. Os resultados foram comparados a um perfil típico de condução com mudanças de marcha a 3000 rpm e reduções de marcha a 1000 rpm. A solução da otimização global obteve 11,55% de melhoria na economia de combustível FTP, mas houve redução de 14,30% na economia de combustível HWFET. As soluções encontradas pelo AG nas otimizações específicas alcançaram melhorias de 13,71% naeconomia de combustível no teste FTP e 1,53% na economia de combustível no teste HWFET. Em todas as otimizações foram obtidas melhorias no tempo de 0 a 100 km/h de até 3,79%. Os resultados demonstraram que o algoritmo genético conseguiu obter bons resultados nas otimizações específicas.
Problems of distance education in the context of philosophy of personal education
Authors:   Siberian Federal University, Ditkovskaya I.E.
Published: April 2021

Analyzed is experience of distance education in the context of the coronavirus pandemic. In the context of education quality problems, attention is drawn to the inability of most students to organize their independent work and low motivation for independent mastering of the specialty. Meanwhile, under conditions of rapid development of technologies, rapidly changing economic conditions, flexible and timely planning in the context of overcoming the production crisis, specialists, who possess modern technologies in a narrow field, programming languages and the skills of working on specific equipment, are required. But, at the same time, employers are interested in well-educated and big-minded professionals, for example, crisis managers. Graduates should have broad knowledge that allows them to quickly adapt to new requirements, independently choose and master new professions in the future, receiving necessary education, navigate growing flows of information, strive for self-education and self-development, which should be based on the motivation of independent learning. The article focuses on the role of humanitarian knowledge, mastery of which is the basis for self-education and self-development. The definition of the concept of “philosophy of personal education” as a system of thinking in which the principles of philosophy of education are projected onto a personal assessment of one’s own physical, intellectual, spiritual, moral and ethical potential as a foundation for self-education and self-development is given. On the basis of philosophy of personal education, abilities, intellectual and creative potential of the individual are realized and a clear motivation for the need to master a particular specialty and self-improvement in this area is determined.
Methodological support for spiritual and moral education at various age stages of development
Authors:   Moscow City Pedagogical University, Ivanov А.V.
Published: April 2021

Researched are problems of spiritual and moral education of children and adolescents at various age stages, identifying the content and methods of their spiritual and moral development. The following age periods are considered: preschool age, primary school age, adolescence and adolescence, taking into account the leading activity (according to L.S. Vygotsky and D.B. Elkonin), the level of intellectual and moral development (L. Kohlberg, J. Piaget), self-awareness. The age characteristics of children and adolescents also determine the specific ways of educational work from preschool story-role-playing games to discussions, trainings, conferences, group work in older adolescence and youth. The article presents the content and methods of spiritual and moral education and self-education, areas of activity identified in the course of empirical research. The purpose of spiritual and moral education is aimed at developing spiritual qualities that ensure the development of the spiritual consciousness of children, adolescents and youth in accordance with the tasks of the new education, which characterizes the expansion of consciousness by realizing its relationship with the Cosmos, with the deep processes of the evolutionary development of mankind, overcoming the narrow framework of personal egoistic consciousness. The materials of the article are of practical value for researchers of educational problems, students and also school teachers.
Improving the system of additional professional education for teachers-choreographers
Authors:   Tyumen State Institute of Culture, Sheregova V.A. , Postelnyak A.I. , Medvedeva S.V. , Medvedev A.S.
Published: April 2021

Examined is specifics of professional activities of teachers choreographers under modern conditions. The increasing requirements for the competence of specialists are noted in connection with the increasingly complex conditions of their professional activities. The need to improve the system of training and advanced training is being actualized, taking into account the specifics of the problems they have to face. The results of a survey of coaches and judges of the regional sports Federation of dance sports of the Tyumen region are presented. Various aspects that characterize the problem field of the modern system of ballroom dancing have been studied. The assessment of the content characteristics of refresher courses that the respondents periodically take. The gaps in the system of professional development of teachers-choreographers that need to be eliminated are shown. A concept is proposed that can form the basis of additional education programs for ballroom dance teachers. The concept is based on a differentiated approach and includes four main stages. The result of professional development of specialists should be the implementation of the following main functions of the system of additional education: restorative, compensatory, innovative, corrective, the function of forming creative activity.
Content security and Content regulation
Authors:   MIREA – Russian Technological University, Shalin A.P.
Published: April 2021

Discussed is the growing influence of the Internet and social networks on modern society and the formation of a young person’s personality. Due to the development of digital and telecommunication technologies, the number of treats and crimes in this field has been increasing. Thus, the problem of content security and violent content faced by the state and society has never been as acute as in recent years. The article discusses the existing content management systems and their features and briefly describes the activity of the Federal service for supervision of oommunication and information technology Roskomnadzor, as well as its successes and shortcomings. It also describes steps taken by the state in the field of content management and provides examples of existing regulations in the Russian Federation. The article discusses the role of social welfare organizations in the creation of safe cyberspace. It lists public organizations that existed in Russia and were involved in content management and security activities. With the abundance of violent content, some of results obtained by these organizations and solutions they use can be reused to develop a secure virtual environment today.
Globalização e teoria social contemporânea
Authors: Arnaut Danilo
Published: April 2021

O propósito deste artigo é discutir alguns dos desafios metodológicos enfrentados no desenvolvimento de minhas pesquisas sobre a problemática da globalização nas ciências sociais. O que segue, contudo, não corresponde a um conjunto de teorias, teses ou diagnósticos a respeito da globalidade emergente. De certo modo, aliás, a globalização, em si, nem mesmo constitui o objeto principal desta reflexão: a intenção é investigar as trilhas de pensamento e sensibilidade percorridas pelos estudiosos da globalização – em especial, Octavio Ianni e Ulrich Beck, que foram os escolhidos na composição do recorte investigativo. Esta reflexão será dividida em quatro partes. Primeiro, trato da própria construção do objeto da pesquisa. Em seguida, cabe abordar também a construção da própria pesquisa. Com base nisso, procuro compartilhar algumas das dificuldades procedimentais no trato dos escritos trabalhados, buscando apresentar alguns caminhos metodológicos para o seu enfrentamento e também para a compreensão do seu status teórico-epistemológico. Por fim, reflito sobre a prática interpretativa de explicações sociológicas como as abordadas aqui.
A construção da realidade na perspectiva relacional de Pierre Bourdieu
Authors: Silva Danilo Manoel Farias da
Published: April 2021

Falar do que vem a ser a “construção da realidade” é um tema transdisciplinar e interdisciplinar envolvendo distintas abordagens cientificas. Esse problema estápresente desde a filosofia (vontade e representação), passando pela linguística (linguagemestruturando a realidade/construção da realidade social), a psicanálise (princípios darealidade psíquica), sociologia (construção social da realidade), antropologia (significaçãoda norma cultural/formas de representação) e até a física teórica (visão da matéria na relação com o objeto/ posição do observador no espaço). No entanto, por mais queesse debate no nosso campo das ciências sociais seja conhecido a partir da sociologia doconhecimento (Berger e Luckmann), este trabalho se propõe a uma abordagem diferentea partir da perspectiva relacional de Pierre Bourdieu. Este ensaio tem como objetivouma sistematização metodológica da discussão acerca da construção da realidade nopensamento de Bourdieu, além de discutir acerca do caráter social e cientifico que envolve a compreensão do que vem a ser a “realidade” e as possibilidades de sua representação, percepção e decodificação.