bluuebunny/crossref_metadata_2025 huggingface dataset:
Implication of ornithine acetyltransferase activity on l‐ornithine production in Corynebacterium glutamicum
Authors: Hao Ning , Mu Jingrui , Hu Nan , Xu Sheng , Shen Peng , Yan Ming , Li Yan , Xu Lin
Published: January 2015

l‐Ornithine is an intermediate of the l‐arginine biosynthetic pathway in Corynebacterium glutamicum. The effect of ornithine acetyltransferase (OATase; ArgJ) on l‐ornithine production was investigated, and C. glutamicum 1006 was engineered to overproduce l‐ornithine as a major product by inactivating regulatory repressor argR gene and overexpressing argJ gene. A genome sequence analysis indicated that the argF gene encoding ornithine carbamoyltransferase in C. glutamicum 1006 was mutated, resulting in the accumulation of a certain amount of l‐ornithine (20.5 g/L). The assays using a crude extract of C. glutamicum 1006 indicated that the l‐ornithine concentration for 50% inhibition of OAT was 5 mM. To enhance l‐ornithine production, the argJ gene from C. glutamicum ATCC 13032 was overexpressed. In flask cultures, the resulting strain, C. glutamicum 1006∆argR‐argJ, produced 31.6 g/L l‐ornithine, which is 54.15% more than that produced by C. glutamicum 1006. The OAT activity of C. glutamicum 1006∆argR‐argJ was significantly greater than that of C. glutamicum 1006, and this study achieved the highest conversion ratio of sugar to acid (0.396 g/g) compared with those of previous reports. ArgJ strongly influences the production of l‐ornithine in C. glutamicum.
Effects of even and odd number fatty acids cofeeding on PHA production and composition in Pseudomonas putida Bet001 isolated from palm oil mill effluent
Authors: Mohd Razaif‐Mazinah Mohd Rafais , Mohamad Annuar Mohamad Suffian , Sharifuddin Yusrizam
Published: January 2015

The biosynthesis of medium‐chain‐length poly‐3‐hydroxyalkanoates by Pseudomonas putida Bet001 cultivated on mixed carbon sources was investigated. The mixed carbon sources consisted of heptanoic acid (HA) and oleic acid (OA). A relatively low PHA content at 1.2% (w/w) and 11.4% (w/w) was obtained when HA or OA was used as the sole carbon source. When these fatty acids were supplied as a mixture, PHA content increased threefold. Interestingly, the mixture‐derived PHA composed of both odd and even monomer units, namely. 3‐hydroxyheptanoate, 3‐hydroxyoctanoate, 3‐hydroxydecanoate, and 3‐hydroxydodecanoate and no unsaturated monomer was detected. It is hypothesized that the even‐numbered monomers were derived primarily from OA, whereas the odd‐numbered monomer was derived from HA. This also points out to an efficient and yet distinct fatty acids metabolism that fed the PHA biosynthesis machinery of this particular microorganism. PHA obtained was elastomeric because melting temperature (Tm) and crystallinity were absent. It showed good thermal stability with degradation temperature (Td) ranging from 275.96 to 283.05 °C.
Study on the mechanism of the interaction between acteoside and pepsin using spectroscopic techniques
Authors: Fang Yifeng , Xu Hong , Shen Liangliang , Huang Fengwen , Yibulayin Shadaiti , Huang Songyang , Tian Shengli , Hu Zhangli , He Zhendan , Li Fangrong , Li Yinong , Zhou Kai
Published: January 2015

The interaction of acteoside with pepsin has been investigated using fluorescence spectra, UV/vis absorption spectra, three‐dimensional (3D) fluorescence spectra and synchronous fluorescence spectra, along with a molecular docking method. The fluorescence experiments indicate that acteoside can quench the intrinsic fluorescence of pepsin through combined quenching at a low concentration of acteoside, and static quenching at high concentrations. Thermodynamic analysis suggests that hydrogen bonds and van der Waal's forces are the main forces between pepsin and acteoside. According to the theory of Förster's non‐radiation energy transfer, the binding distance between pepsin and acteoside was calculated to be 2.018 nm, which implies that energy transfer occurs between acteoside and pepsin. In addition, experimental results from UV/vis absorption spectra, 3D fluorescence spectra and synchronous fluorescence spectra imply that pepsin undergoes a conformation change when it interacts with acteoside. Copyright © 2015 John Wiley & Sons, Ltd.
Meta-analysis of complication rates for single-loop versus dual-loop (Roux-en-Y) with isolated pancreaticojejunostomy reconstruction after pancreaticoduodenectomy
Authors: Klaiber U , Probst P , Knebel P , Contin P , Diener M K , Büchler M W , Hackert T
Published: January 2015

Background

Postoperative pancreatic fistula is one of the most important and potentially severe complications after partial pancreaticoduodenectomy. In this context, the reduction of postoperative pancreatic fistula by means of a dual-loop (Roux-en-Y) reconstruction with isolation of the pancreaticojejunostomy from biliary drainage has been evaluated in several studies. This systematic review and meta-analysis summarizes evidence of effectiveness and safety of the isolation of the pancreaticojejunostomy compared with conventional single-loop reconstruction.

Methods

Randomized clinical trials (RCTs) and controlled clinical trials (CCTs) comparing outcomes of dual-loop reconstruction with isolated pancreaticojejunostomy and single-loop reconstruction were searched according to PRISMA guidelines. Random-effects meta-analyses were performed and the results presented as weighted risk ratios or mean differences with their corresponding 95 per cent c.i.

Results

Of 83 trials screened for eligibility, three RCTs and four CCTs including a total of 802 patients were finally included. Quantitative synthesis showed no significant statistical difference between the two procedures regarding postoperative pancreatic fistula, delayed gastric emptying, haemorrhage, intra-abdominal fluid collection or abscess, bile leakage, wound infection, pneumonia, overall morbidity, mortality, reinterventions, reoperations, perioperative blood loss and length of hospital stay. Duration of surgery was significantly longer in patients undergoing dual-loop reconstruction.

Conclusion

Dual-loop (Roux-en-Y) reconstruction with isolated pancreaticojejunostomy after partial pancreaticoduodenectomy is not superior to single-loop reconstruction regarding pancreatic fistula rate or other relevant outcomes. Additional superiority trials are therefore not warranted, although a high-quality trial may be justified to prove equivalence or non-inferiority.
Education mitigates age‐related decline in N‐Acetylaspartate levels
Authors: Erickson Kirk I. , Leckie Regina L. , Weinstein Andrea M. , Radchenkova Polina , Sutton Bradley P. , Prakash Ruchika Shaurya , Voss Michelle W. , Chaddock‐Heyman Laura , McAuley Edward , Kramer Arthur F.
Published: January 2015

Background

Greater educational attainment is associated with better neurocognitive health in older adults and is thought to reflect a measure of cognitive reserve. In vivo neuroimaging tools have begun to identify the brain systems and networks potentially responsible for reserve.

Methods

We examined the relationship between education, a commonly used proxy for cognitive reserve, and N‐acetylaspartate (NAA) in neurologically healthy older adults (N = 135; mean age = 66 years). Using single voxel MR spectroscopy, we predicted that higher levels of education would moderate an age‐related decline in NAA in the frontal cortex.

Results

After controlling for the variance associated with cardiorespiratory fitness, sex, annual income, and creatine levels, there were no significant main effects of education (B = 0.016, P = 0.787) or age (B = −0.058, P = 0.204) on NAA levels. However, consistent with our predictions, there was a significant education X age interaction such that more years of education offset an age‐related decline in NAA (B = 0.025, P = 0.031). When examining working memory via the backwards digit span task, longer span length was associated with greater education (P < 0.01) and showed a trend with greater NAA concentrations (P < 0.06); however, there was no age X education interaction on digit span performance nor a significant moderated mediation effect between age, education, and NAA on digit span performance.

Conclusions

Taken together, these results suggest that higher levels of education may attenuate an age‐related reduction in neuronal viability in the frontal cortex.
Enhancement and Induction of HIV‐1 Infection through an Assembled Peptide Derived from the CD4 Binding Site of gp120
Authors: Groß Andrea , Rödel Katja , Kneidl Barbara , Donhauser Norbert , Mössl Marek , Lump Edina , Münch Jan , Schmidt Barbara , Eichler Jutta
Published: January 2015

Contact between the human immunodeficiency virus (HIV‐1) and its target cell is initiated by the interaction of viral gp120 with cellular CD4. An assembled peptide (CD4bs‐M) that presents the CD4 binding site of gp120 was previously shown to inhibit the gp120–CD4 interaction. Here, we demonstrate that CD4bs‐M selectively enhances infection of cells with HIV‐1, whereas infection with herpes simplex virus remains largely unaffected. The effects of CD4bs‐M variants containing D‐amino acids, or prolines at selected positions, point to the importance of side chain orientation and spatial orientation of this fragment. Furthermore, CD4bs‐M was shown to assemble into amyloid‐like fibrils that capture HIV‐1 particles, which likely contributes to the infection‐enhancing effect. Beyond infection enhancement, CD4bs‐M enabled HIV‐1 infection of CD4‐negative cells, suggesting that binding of the peptide to gp120 facilitates interaction of gp120 with coreceptors, which might in turn enhance HIV‐1 entry.
How bifurcation angle impacts the fate of side branch after main vessel stenting: A retrospective analysis of 1,200 consecutive bifurcation lesions in a single center
Authors: Zhang Dong , Xu Bo , Yin Dong , Li Yiping , He Yuan , You Shijie , Qiao Shubin , Wu Yongjian , Yan Hongbing , Yang Yuejin , Gao Runlin , Dou Kefei
Published: January 2015

Objectives

We aimed to investigate the effect of bifurcation angle (BA) on side branch (SB) occlusion after main vessel (MV) stenting. Background: BA is thought to impact the risk of SB occlusion in coronary bifurcation patients undergoing percutaneous coronary intervention (PCI).

Methods

A total of 1,171 consecutive patients with 1,200 bifurcation lesions undergoing one stent or provisional two stent techniques were studied. The lesions were divided into low angle and high angle groups using the median BA (52°). Multivariate logistic regression analysis was performed to identify independent predictors of SB occlusion.

Results

SB occlusion occurred in 88 (7.33%) of 1,200 bifurcation lesions treated with the one stent technique or MV stenting first strategy. The rate of SB occlusion was significantly higher in the high angle group (63/600, 10.5%) than the low angle group (25/600, 4.2%) (P < 0.001). The rate of SB occlusion increased significantly across quartiles of BA as follows: from 3.63% in the first quartile of BA, to 4.71% in quartile II, to 8.14% in quartile III to 12.97% in quartile IV (P < 0.001). Multivariable analysis showed that high angle was an independent predictor of SB occlusion (odds ratio: 1.026, 95% confidence intervals: 1.014–1.037, P < 0.001). Plaque distribution at the same side of SB, MV Thrombolysis in Myocardial Infarction flow grade before stenting, pre‐procedural diameter stenosis of bifurcation core, diameter ratio between MV/SB and diameter stenosis of SB before MV stenting were also independent predictors of SB occlusion.

Conclusions

High BA was an independent predictor of SB occlusion after MV stenting. The occlusion risk of SB with a high BA should not be ignored. © 2015 Wiley Periodicals, Inc.
PLATINUM China: A prospective, randomized investigation of the platinum chromium everolimus‐eluting stent in de novo coronary artery lesions
Authors: Gao Runlin , Han Yaling , Yang Yuejin , Zhang Jian , Hou Yuqing , Wang Haichang , Li Hui , Fang Quan , Yu Bo , Xu Bo , Allocco Dominic J. , Dawkins Keith D.
Published: January 2015

Objectives

The PLATINUM China clinical trial evaluated the safety and effectiveness of the thin‐strut, everolimus‐eluting, platinum‐chromium PROMUS™ Element™ stent (PtCr‐EES) (Boston Scientific, Marlborough, MA) for the treatment of patients in China.

Background

Clinical outcomes from the PtCr‐EES have not been evaluated in patients from China, nor has it been directly compared with the second‐generation stainless steel paclitaxel‐eluting TAXUS Liberté stent (PES) in a randomized head‐to‐head trial.

Methods In this prospective, multicenter, single‐blind, superiority trial, patients with a single de novo atherosclerotic coronary artery lesion were randomized 1:3 to receive either the PES or PtCr‐EES. The primary endpoint was in‐stent late loss at 9 months.

Results

Among 127 PES and 373 PtCr‐EES patients (71.2% male; mean age 57.3 years), the primary endpoint of 9‐month in‐stent late loss was 0.40 ± 0.45mm for PES versus 0.11 ± 0.36 mm for PtCr‐EES (P < 0.001). In‐stent % diameter stenosis was 22.20±16.00% for PES versus 11.06±13.86% for PtCr‐EES (P<0.001) at 9 months. The 1‐year rate of death/MI was 1.6% (2/127) for PES versus 0% (0/371) for PtCr‐EES (P=0.06) and target vessel revascularization was 4.7% (6/127) for PES versus 2.7% (10/371) for PtCr‐EES (P=0.26). No stent thromboses occurred at12 months in either group.

Conclusions

In the largest prospective angiographic evaluation conducted to date with this stent, the PROMUS Element PtCr‐EES was superior to the TAXUS Liberté PES for the primary endpoint of late loss at 9 months, with low rates of clinical events at 1 year. Clinical follow‐up will continue to 2 years. © 2015 Wiley Periodicals, Inc.
Probing The Structure Evolution of Iron‐Based Fischer–Tropsch to Produce Olefins by Operando Raman Spectroscopy
Authors: Fu Donglong , Dai Weiwei , Xu Xinchao , Mao Wei , Su Junjie , Zhang Zhengpai , Shi Bianfang , Smith Julian , Li Ping , Xu Jing , Han Yi‐Fan
Published: January 2015

By using operando Raman spectroscopy (ORS), we investigated the panoramic structure evolution of an iron oxide (α‐Fe2O3) catalyst, which is used for the production of olefins via Fischer–Tropsch (FTO). During activation in different atmospheres and reaction at 260 °C and 3.0 MPa, α‐Fe2O3 was only partially transformed into γ‐Fe2O3 by H2 pretreatment; meanwhile, a transformation of α‐Fe2O3→γ‐Fe2O3→Fe3O4→Fe5C2 was observed in both CO and syngas (H2/CO). Combining with other techniques such as XRD, TEM, XPS and TPSR, we reveal that assembles of various iron oxides (γ‐Fe2O3, Fe3O4, Fe carbide, and their combinations) are responsible for FTO. Especially, the preliminary relationship of catalyst structure and performance relating to the production of olefins directly from syngas was established. Such a study is critical for further understanding of the FTO reaction and other catalytic reactions.
Electrodeposition of Crystalline Gallium‐Doped Germanium and SixGe1−x from an Ionic Liquid at Room Temperature
Authors: Lahiri Abhishek , Olschewski Mark , Carstens Timo , El Abedin Sherif Zein , Endres Frank
Published: January 2015

In this paper, we show the electrodeposition of both gallium‐doped crystalline germanium and SixGe1−x directly on copper at room temperature from an ionic liquid. Germanium and SixGe1−x were electrodeposited on a thin layer of electrodeposited gallium on copper, thereby leading to the formation of crystalline gallium‐doped germanium and SixGe1−x. From the microstructure, it appears that Ge and SixGe1−x dissolve in Ga to form an amalgam, which then recrystallises to form a crystalline structure. X‐ray diffraction confirmed the formation of crystalline phases. The indirect band gap of the gallium‐doped germanium measured by using scanning tunnelling spectroscopy is (0.9±0.1) eV.
Palladium‐Catalyzed Direct C2‐Arylation of an N‐Heterocyclic Carbene: An Atom‐Economic Route to Mesoionic Carbene Ligands
Authors: Ghadwal Rajendra S. , Reichmann Sven O. , Herbst‐Irmer Regine
Published: January 2015

Blocking the C2 position of an imidazole‐derived classical N‐heterocyclic carbene (NHC) with an aryl group is an essential strategy to establish a route to mesoionic carbenes (MICs), which coordinate to the metal via the C4 (or C5) carbon atom. An efficient catalytic route to MIC precursors by direct arylation of an NHC is reported. Treatment of 1,3‐bis(2,6‐diisopropylphenyl)imidazol‐2‐ylidene (IPr) with an aryl iodide (RC6H4I) in the presence of 0.5 mol % of [Pd2(dba)3] (dba=dibenzylideneacetone) precatalyst affords the C2‐arylated imidazolium salts {IPr(C6H4R)}I (R=H, 4‐Me, 2‐Me, 4‐OMe, 4‐COOMe) in excellent (up to 92 %) yields. Treatment of {IPr(C6H5)}I with CuI and KN(SiMe3)2 exclusively affords the MIC–copper complex [(IPrPh)CuI].
Promotion of Double‐Duplex Invasion of Peptide Nucleic Acids through Conjugation with Nuclear Localization Signal Peptide
Authors: Aiba Yuichiro , Honda Yuta , Komiyama Makoto
Published: January 2015

Pseudo‐complementary peptide nucleic acid (pcPNA), as one of the most widely used synthetic DNA analogues, invades double‐stranded DNA according to Watson–Crick rules to form invasion complexes. This unique mode of DNA recognition induces structural changes at the invasion site and can be used for a range of applications. In this paper, pcPNA is conjugated with a nuclear localization signal (NLS) peptide, and its invading activity is notably promoted both thermodynamically and kinetically. Thus, the double‐duplex invasion complex is formed promptly at low pcPNA concentrations under high salt conditions, where the invasion otherwise never occurs. Furthermore, NLS‐modified pcPNA is successfully employed for site‐selective DNA scission, and the targeted DNA is selectively cleaved under conditions that are not conducive for DNA cutters using unmodified pcPNAs. This strategy of pcPNA modification is expected to be advantageous and promising for a range of in vitro and in vivo applications.
Is PdII‐Promoted σ‐Bond Metathesis Mechanism Operative for the PdPEPPSI Complex‐Catalyzed Amination of Chlorobenzene with Aniline? Experiment and Theory
Authors: Wang Feiqun , Zhu Lei , Zhou Yunfei , Bao Xiaoguang , Schaefer Henry F.
Published: January 2015

Reduction of the PdPEPPSI precatalyst to a Pd0 species is generally thought to be essential to drive Buchwald–Hartwig amination reactions through the well‐ documented Pd0/PdII catalytic cycle and little attention has been paid to other possible mechanisms. Considered here is the PdPEPPSI‐catalyzed aryl amination of chlorobenzene with aniline. A neat reaction system was used in new experiments, from which the potentially reductive roles of the solvent and labile ligand of the PEPPSI complex in leading to Pd0 species are ruled out. Computational results demonstrate that anilido‐containing PdII intermediates involving σ‐bond metathesis in pathways leading to the diphenylamine product have relatively low barriers. Such pathways are more favorable energetically than the corresponding reductive elimination reactions resulting in Pd0 species and other putative routes, such as the PdII/PdIV mechanism, single electron transfer mechanism, and halide atom transfer mechanism. In some special cases, if reactants/additives are inadequate to reduce a PdII precatalyst, a PdII‐involved σ‐bond metathesis mechanism might be feasible to drive the Buchwald–Hartwig amination reactions.
ChemInform Abstract: Single Crystal and Magnetic Structures of Maricite‐Type AgMnVO4.
Authors: Ben Yahia Hamdi , Shikano Masahiro , Gaudin Etienne , Avdeev Maxim , Ling Chris D.
Published: January 2015

Polycrystalline AgMnVO4 is prepared by solid state reaction of stoichiometric amounts of Ag2O, MnO, and V2O5 according to the literature.
ChemInform Abstract: Synthesis and Electrochemical Performances of Maricite‐NaMPO4 (M: Ni, Co, Mn) Electrodes for Hybrid Supercapacitors.
Authors: Senthilkumar Baskar , Sankar Kalimuthu Vijaya , Vasylechko Leonid , Lee Yun‐Sung , Selvan Ramakrishnan Kalai
Published: January 2015

The title compounds are prepared by solution combustion synthesis from aqueous solutions of stoichiometric amounts of M(NO3)2 (M: Ni, Co, Mn), NaNO3, NH4H2PO4, and glycine (200—300 °C, 10 min), followed by calcination of the foamy product (400—700 °C, 3 h).
ChemInform Abstract: pH and Ligand Dependent Assembly of Well—Dawson Arsenomolybdate Capped Architectures.
Authors: Zhang He , Yu Kai , Wang Chunmei , Su Zhanhua , Wang Chunxiao , Sun Di , Cai Honghong , Chen Zhaoyi , Zhou Baibin
Published: January 2015

Compounds (IV)—(VIII) are hydrothermally synthesized via altering pH values and organic ligand of the reaction system.
ChemInform Abstract: The U5+ Compound Ba9Ag10U4S24: Synthesis, Structure, and Electronic Properties.
Authors: Mesbah Adel , Stojko Wojciech , Lebegue Sebastien , Malliakas Christos D. , Frazer Laszlo , Ibers James A.
Published: January 2015

Black crystals of the new title compound are prepared by solid state reaction of a stoichiometric mixture of BaS, Ag, U, and S (evacuated silica tube, 1273 K, 8 d, 3 K/h cooling rate).
ChemInform Abstract: Asymmetric One‐Pot Synthesis of 1,3‐Oxazolidines and 1,3‐Oxazinanes via Hemiaminal Intermediates.
Authors: Nimmagadda Sri Krishna , Zhang Zuhui , Antilla Jon C.
Published: January 2015

The reaction proceeds via the formation of hemiaminal intermediates obtained by the enantioselective addition of alcohols to imines catalyzed by a chiral magnesium phosphate catalyst, followed by intramolecular cyclization under mildly basic conditions.
ChemInform Abstract: Efficient and Regioselective Synthesis of Bicyclic Pyrrolidones or Bicyclic Pyridones by Cyclocondensation of Heterocyclic Ketene Aminals with Nitro‐phenylpropiolate.
Authors: Fan Juan , Yang Qin‐Yi , He Guo‐Jin , Xie Xiao‐Guang , Zhu Hong‐You , Jin Yi , Lin Jun
Published: January 2015

The first examples of regioselective cyclocondensation of hetereocyclic ketene aminals with nitrophenylpropiolates are described.
ChemInform Abstract: Synthesis of Trifluoromethyl‐Substituted 3‐Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery.
Authors: Artamonov Olexiy S. , Slobodyanyuk Evgeniy Y. , Volochnyuk Dmitriy M. , Komarov Igor V. , Tolmachev Andrey A. , Mykhailiuk Pavel K.
Published: January 2015

Title compounds are prepared by CuCl‐mediated trifluoromethylcyclopropanation of cyclic enamides (I), (VI), and (IX) with CF3‐CHN2.
ChemInform Abstract: Synthesis of Substituted Biaryls Through Gold‐Catalyzed Petasis—Ferrier Rearrangement of Propargyl Ethers.
Authors: Pati Kamalkishore , Alabugin Igor V.
Published: January 2015

A new approach for the preparation of biaryl derivatives is developed by using the gold‐catalyzed cycloisomerization of propargylbenzyl methyl ethers under mild reaction conditions.
ChemInform Abstract: Highly Efficient Homogeneous and Heterogenized Ruthenium Catalysts for Transfer Hydrogenation of Carbonyl Compounds.
Authors: Ganesamoorthy S. , Jerome P. , Shanmugasundaram K. , Karvembu R.
Published: January 2015

Both ruthenium catalysts show high catalytic activity towards transfer hydrogenation of carbonyl compounds using isopropanol as hydrogen donor as well as solvent.
ChemInform Abstract: Ruthenium‐Catalyzed N‐Alkylation of Amines with Alcohols under Mild Conditions Using the Borrowing Hydrogen Methodology.
Authors: Enyong Arrey B. , Moasser Bahram
Published: January 2015

The successful application of an aminoamide ligand for the ruthenium‐catalyzed alkylation of amines under mild conditions is demonstrated.
ChemInform Abstract: A Mn(III)/TEMPO‐co‐Mediated Tandem Azidation—1,2‐Carbon Migration Reaction of Allylic Silyl Ethers.
Authors: Chen Zhi‐Min , Zhang Zhen , Tu Yong‐Qiang , Xu Ming‐Hui , Zhang Fu‐Min , Li Chen‐Chen , Wang Shao‐Hua
Published: January 2015

The title reaction enables the difunctionalization of unactivated alkenes such as (I) and (III) through simultaneous construction of an alkyl azide and an all‐carbon quaternary centre.
ChemInform Abstract: Catalytic and Highly Enantioselective Friedel—Crafts Type Reactions of Heteroaromatic Compounds with Trifluoropyruvate and Glyoxylate by a Dicationic Palladium Complex.
Authors: Aikawa Kohsuke , Asai Yuya , Hioki Yuta , Mikami Koichi
Published: January 2015

This asymmetric Friedel‐Crafts type reaction yields substituted furan, thiophene, and pyrrole derivatives with high enantioselectivity.
ChemInform Abstract: Palladium‐Catalyzed Cross‐Coupling Reaction of Diazo Compounds and Vinyl Boronic Acids: An Approach to 1,3‐Diene Compounds.
Authors: Xia Yamu , Xia Ying , Liu Zhen , Zhang Yan , Wang Jianbo
Published: January 2015

A novel approach to 1,3‐dienes having one double bond in a carbocyclic or oxacyclic ring by Pd‐catalyzed coupling of α‐diazoketones and lactones with vinyl boronic acids is presented.
ChemInform Abstract: Enantioselective Heterogeneous Synergistic Catalysis for Asymmetric Cascade Transformations.
Authors: Deiana Luca , Ghisu Lorenza , Afewerki Samson , Verho Oscar , Johnston Eric V. , Hedin Niklas , Bacsik Zoltan , Cordova Armando
Published: January 2015

A silica‐supported chiral amine and diaminopalladium complex is synthesized.
ChemInform Abstract: Atom‐Economical Access to Highly Substituted Indenes and Furan‐2‐ones via Tandem Reaction of Diazo Compounds and Propargyl Alcohols.
Authors: Muthusamy Sengodagounder , Sivaguru Manickasamy
Published: January 2015

A facile and efficient protocol for the tandem reaction of α‐diazoamides or α‐diazoesters with propargyl alcohols to produce highly substituted furanone and indene derivatives is presented.
ChemInform Abstract: Branch‐Selective Allylic C—H Carboxylation of Terminal Alkenes by Pd/sox Catalyst.
Authors: Kondo Hiroki , Yu Feng , Yamaguchi Junichiro , Liu Guosheng , Itami Kenichiro
Published: January 2015

An allylic C—H carboxylation in presence of palladium diacetate catalyst with sulfoxide‐oxazoline ligand and benzoquinone as oxidant furnishes the corresponding branched allylic esters with high regioselectivity.
ChemInform Abstract: Oxidative Trifluoromethylthiolation of Terminal Alkynes with AgSCF3: A Convenient Approach to Alkynyl Trifluoromethyl Sulfides.
Authors: Zhu Sheng‐Qing , Xu Xiu‐Hua , Qing Feng‐Ling
Published: January 2015

The reaction proceeds via N‐(trifluoromethylsulfenyl)succinimide as reactive intermediate.
ChemInform Abstract: Gold‐Catalyzed Intermolecular Synthesis of Alkylidenecyclopropanes Through Catalytic Allene Activation.
Authors: Sabbatani Juliette , Huang Xueliang , Veiros Luis F. , Maulide Nuno
Published: January 2015

A gold‐catalyzed methylenecyclopropanation of amino‐substituted allenes using diphenylsulfonium ylides derived from activated methylene compounds as an interesting safe alternative to diazo compounds is presented.
ChemInform Abstract: Copper(I)‐Promoted Alkylation of Alkenylbenzyldimethylsilanes.
Authors: Takeda Takeshi , Matsumura Ryo , Wasa Hideki , Tsubouchi Akira
Published: January 2015

The alkylation reagents can be alkyl, allyl, and benzyl halides.
ChemInform Abstract: Efficient Copper‐Catalyzed Trifluoromethylation of Aromatic and Heteroaromatic Iodides: The Beneficial Anchoring Effect of Borates.
Authors: Gonda Zsombor , Kovacs Szabolcs , Weber Csaba , Gati Tamas , Meszaros Attila , Kotschy Andras , Novak Zoltan
Published: January 2015

The novel method for the copper‐catalyzed trifluoromethylation of aromatic and heteroaromatic iodides uses silane (II) in the presence of trimethyl borate.
ChemInform Abstract: Electrochemical Synthesis of Copper Nanoparticles on Nafion—Graphene Nanoribbons and Its Application for the Synthesis of Diaryl Ethers.
Authors: Singh Abhilash S. , Shendage Suresh S. , Nagarkar Jayashree M.
Published: January 2015

The title catalyst is successfully employed for the Ullmann type coupling of phenols with aromatic halides to produce diaryl ethers in generally good yields.
ChemInform Abstract: Gold‐Catalyzed 1,3‐Transposition of Ynones.
Authors: Kazem Shiroodi Roohollah , Soltani Mohammad , Gevorgyan Vladimir
Published: January 2015

The analog of (Ie) bearing a phenyl instead of a 2‐tolyl group is shown to be less reactive providing a mixture of the regioisomeric starting material and product.
ChemInform Abstract: Efficient Cyanation of Aryl Halide with K4[Fe(CN)6]·3H2O Catalyzed by a P—O Bidentate Chelate Palladium Complex under Air.
Authors: Fu Leiqing , Li Xiaogang , Zhu Qiming , Chen Sanbao , Kang Yanping , Guo Mengping
Published: January 2015

Aryl chlorides react more slowly and furnish a little lower product yield.
ChemInform Abstract: Copper‐Catalyzed Synthesis of Aryl and Alkyl Trifluoromethyl Sulfides Using CF3SiMe3 and Na2S2O3 as —SCF3 Source.
Authors: Zhong Wei , Liu Xiaoming
Published: January 2015

The copper‐catalyzed trifluoromethylation of aryl halides, tosylates, mesylates as well as alkyl iodides proceeds via S‐aryl or S‐alkyl sulfothioate intermediates to give the corresponding trifluoromethyl sulfides.
ChemInform Abstract: An Efficient and New Protocol for Phosphine‐Free Suzuki Coupling Reaction Using Palladium‐Encapsulated and Air‐Stable MIDA Boronates in an Aqueous Medium.
Authors: Mendes da Silva Joaquim Fernando , Yepes Perez Andres Felipe , Pinto de Almeida Natalia
Published: January 2015

The novel method using palladium microencapsulated in a polyurea matrix as the catalyst allows the Suzuki—Miyaura coupling of aryl halides with arylboronic acid esters (I) and (IV) in aqueous ethanol.
ChemInform Abstract: K‐Bis(2‐ethylhexyl) Phosphate (BEHPK): A Novel Additive for C—H Arylation.
Authors: Seki Masahiko
Published: January 2015

A wide range of functionalized biaryls are obtained by facile, efficient, and economical Ru‐mediated direct C—H arylation using readily available K‐bis(2‐ethylhexyl) phosphate (BEHPK) as additive.
ChemInform Abstract: Oxidative Cleavage of 1,3‐Disubstituted Benzo[c]furans with Activated Manganese Dioxide: A Facile Preparation of 1,2‐Di(het)aroylbenzenes.
Authors: Sivasakthikumaran Ramakrishnan , Nandakumar Meganathan , Mohanakrishnan Arasambattu
Published: January 2015

The cleavage of 2,5‐diaryl substituted furanes is unsuccessful.
ChemInform Abstract: Palladium Nanoparticles Supported on Triazine Functionalized Mesoporous Covalent Organic Polymers as Efficient Catalysts for Mizoroki—Heck Cross Coupling Reaction.
Authors: Puthiaraj Pillaiyar , Pitchumani Kasi
Published: January 2015

A novel class of mesoporous covalent organic polymers is synthesized by nucleophilic substitution of cyanuric chloride with 2,2′‐dihydroxybiphenyl.
ChemInform Abstract: Lewis‐Base‐Catalyzed Annulations of Nitroallylic Acetates as C3 Synthons with Electron‐Deficient Alkenes.
Authors: Chen Rongshun , Fan Xia , Gong Junyu , He Zhengjie
Published: January 2015

The title reaction gives multi‐substituted cyclopentenes and spirocyclopenteneoxindoles through a cascade [3+2] cycloaddition/allylic alkylation.
ChemInform Abstract: Rhodium(III)‐Catalyzed Directed peri‐C—H Alkenylation of Anthracene Derivatives.
Authors: Karthikeyan Jaganathan , Yoshikai Naohiko
Published: January 2015

The selective monoalkylation of anthracene‐9‐carboxamides with electron‐deficient olefins is reported.
ChemInform Abstract: A Highly Diastereoselective Five‐Component Synthesis of 1‐(Alkylimino)‐5,5‐dicyano‐3a‐aryloctahydro‐3‐oxacyclobuta [cd]pentalene‐1a,2,5a,5b(2H,3aH)‐tetracarboxylates.
Authors: Adib Mehdi , Sheikhi Ehsan , Haghshenas Pouyan , Rajai‐Daryasarei Saideh , Bijanzadeh Hamid Reza , Zhu Long‐Guan
Published: January 2015

The novel 1:1:1:2 addition reaction of phenacyl bromide, malononitrile, isocyanide, and acetylenedicarboxylate provides the polycyclic product (V) as the only one of 16 possible diastereomers.
ChemInform Abstract: Guanidinium Ylide Mediated Aziridination from Arylaldehydes: Scope and Limitations in the Formation of Unactivated 3‐Arylaziridine‐2‐carboxylates.
Authors: Oda Yukiko , Hada Kihito , Miyata Marie , Takahata Chisato , Hayashi Yukiko , Takahashi Masato , Yajima Naoki , Fujinami Makiko , Ishikawa Tsutomu
Published: January 2015

The diastereo‐ and enantioselective formation of 3‐arylaziridine‐2‐carboxylates from aryl aldehydes and guanidinium ylides is investigated.
ChemInform Abstract: Stereodivergent Organocatalytic Intramolecular Michael Addition/Lactonization for the Asymmetric Synthesis of Substituted Dihydrobenzofurans and Tetrahydrofurans.
Authors: Belmessieri Dorine , de la Houpliere Alix , Calder Ewen D. D. , Taylor James E. , Smith Andrew D.
Published: January 2015

Enone acids are used as suitable substrates for the preparation of the furan skeleton.
ChemInform Abstract: An Unexpected Addition of Acetic Acid to ortho‐Electron‐Deficient Alkynyl‐Substituted Aryl Aldehydes Catalyzed by Palladium(II) Acetate.
Authors: Zhang Jianbo , Han Xiuling
Published: January 2015

The title addition leads to a convenient synthesis of dihydroisobenzofurans.
ChemInform Abstract: A Simple Route to Polysubstituted Indoles Exploiting Azide Induced Furan Ring Opening.
Authors: Abaev Vladimir T. , Plieva Anastasiya T. , Chalikidi Petrakis N. , Uchuskin Maxim G. , Trushkov Igor V. , Butin Alexander V.
Published: January 2015

An efficient indole synthesis based on thermolysis of 2‐(2‐azidobenzyl)furans (III) and (VI) with attack of the formed nitrene moiety onto the ipso position of furan ring is developed.
ChemInform Abstract: Tandem One‐Pot Palladium‐Catalyzed Coupling of Hydrazones, Haloindoles, and Amines: Synthesis of Amino‐N‐vinylindoles and Their Effect on Human Colon Carcinoma Cells.
Authors: Roche Maxime , Bignon Jerome , Brion Jean‐Daniel , Hamze Abdallah , Alami Mouad
Published: January 2015

Two Csp2—N bonds are formed through two mechanistically distinct reactions in a one‐pot fashion.
ChemInform Abstract: Multimetallic Iridium‐Tin (Ir—Sn3) Catalyst in N‐Acyliminium ion Chemistry: Synthesis of 3‐Substituted Isoindolinones via Intra‐ and Intermolecular Amidoalkylation Reaction.
Authors: Maity Arnab Kumar , Roy Sujit
Published: January 2015

Compounds (VII) do not undergo the expected arylation ‐ an unusual cascade pathway is preferred instead.
ChemInform Abstract: Diastereoselective Synthesis of Fused Lactone‐Pyrrolidinones; Application to a Formal Synthesis of (‐)‐Salinosporamide A.
Authors: Logan Angus W. J. , Sprague Simon J. , Foster Robert W. , Marx Leo B. , Garzya Vincenzo , Hallside Michal S. , Thompson Amber L. , Burton Jonathan W.
Published: January 2015

A mild methodology is developed for the synthesis of a range of fused bicyclic lactone‐pyrrolidinones.
ChemInform Abstract: New Bi‐functional Zinc Catalysts Based on Robust and Easy‐to‐Handle N‐Chelating Ligands for the Synthesis of Cyclic Carbonates from Epoxides and CO2 under Mild Conditions.
Authors: Luo Rongchang , Zhou Xiantai , Zhang Wuying , Liang Zhongxiu , Jiang Jun , Ji Hongbing
Published: January 2015

Several 2,2′‐bipyridine Zn(II) complexes functionalized by imidazolium based ionic liquids are prepared and used as catalysts for the cycloaddition reaction of CO2 and various epoxides (I) to provide cyclic carbonates (III).
ChemInform Abstract: Direct Asymmetric Mannich‐Type Reaction of α‐Isocyanoacetates with Ketimines Using Cinchona Alkaloid/Copper(II) Catalysts.
Authors: Hayashi Masashi , Iwanaga Masaru , Shiomi Noriyuki , Nakane Daisuke , Masuda Hideki , Nakamura Shuichi
Published: January 2015

A syn‐selective enantioselective reaction of aromatic ketimines (I) with α‐isocyanoacetate (II) is developed to permit the asymmetric formation of imidazolines.
ChemInform Abstract: Synthesis of Imidazoles and Pyrimidines Using Palladium‐Catalyzed Decarboxylative Intramolecular Condensation of 1,2,4‐Oxadiazol‐5(4H)‐ones.
Authors: Shimbayashi Takuya , Okamoto Kazuhiro , Ohe Kouichi
Published: January 2015

The reaction can be scaled up.
ChemInform Abstract: Visible‐Light‐Promoted Synthesis of Benzimidazoles.
Authors: Park Sehyun , Jung Jaehun , Cho Eun Jin
Published: January 2015

A simple photo‐promoted reaction of o‐phenylenediamine with aliphatic and aromatic aldehydes is presented to give efficiently 2‐substituted benzimidazoles using air as the oxidant.
ChemInform Abstract: DMAP‐Promoted Cascade C—S/C—N Bonds Formation Approach to 1,3‐Thiazolidin‐4‐ones via Annulation of β‐Ketothioamides with α‐Halocarboxylic Acids at Room Temperature.
Authors: Verma Girijesh Kumar , Shukla Gaurav , Nagaraju Anugula , Srivastava Abhijeet , Singh Maya Shankar
Published: January 2015

A fast, straightforward, and efficient one‐pot two‐step cyclocondensation for the formation of densely functionalized thiazolidin‐4‐ones (III) (16 examples) is developed.
ChemInform Abstract: Chemoselective Copper‐Catalyzed Acylation of Benzothiazoles with Aryl Methyl Ketones.
Authors: Feng Qiang , Song Qiuling
Published: January 2015

Reactions performed under O2 atmosphere always gave lower yield than under N2 atmosphere.
ChemInform Abstract: Copper/N,N,N′,N′‐Tetramethylethylenediamine‐Catalyzed Synthesis of N‐Substituted Benzoheterocycles via C—S Cross‐Coupling at Ambient Temperature in Water.
Authors: Zhao Na , Liu Liang , Wang Fei , Li Jia , Zhang Wu
Published: January 2015

Ortho‐chloro‐ and bromo‐phenols as well as p‐nitroanilines did not react.
ChemInform Abstract: A C—H Functionalization Protocol for the Direct Synthesis of Benzobisthiazole Derivatives.
Authors: Bon Jennifer L. , Feng Daijun , Marder Seth R. , Blakey Simon B.
Published: January 2015

Moreover, this method is successfully applied in the syntheses of cruciform (VII) and thiazolothiazole (VIII).
ChemInform Abstract: A Mild and Efficient Method for Large Scale Synthesis of 3‐Aminocoumarins and Its Further Application for the Preparation of 4‐Bromo‐3‐aminocoumarins.
Authors: Das Deb K. , Sarkar Satavisha , Khan Musawwer , Belal Md. , Khan Abu T.
Published: January 2015

3‐Acetamidocoumarins are converted into 3‐aminocoumarins upon treatment with sulfuric acid.
ChemInform Abstract: Diastereoselective Approach to cis‐4‐Methyl/Thiol‐Pipecolic Esters Based on RCM Reaction and Conjugate Michael Addition.
Authors: Zarate Araceli , Orea Laura , Juarez Jorge R. , Castro Alejandro , Mendoza Angel , Gnecco Dino , Teran Joel L.
Published: January 2015

An efficient method for the diastereoselective synthesis of cis‐4‐methyl‐ as well as cis‐4‐mercaptopipecolic acid esters [cf.
ChemInform Abstract: Synthesis of Multisubstituted 2‐Aminopyrroles/Pyridines via Chemoselective Michael Addition/Intramolecular Cyclization Reaction.
Authors: Qi Xueyu , Xiang Haoyue , He Qian , Yang Chunhao
Published: January 2015

Substituted 3‐halo‐4H‐chromen‐4‐ones react with C,N‐bisnucleophiles under very mild conditions.
ChemInform Abstract: A Tandem Synthesis of N‐(4‐Hydroxyquinolin‐2‐yl)sulfonamides from Sulfonoketenimides and Isatoic Anhydride.
Authors: Yavari Issa , Nematpour Manijeh , Askarian‐Amiri Mohammad
Published: January 2015

The one‐pot synthesis of the title species involves thermal decomposition of isatoic acid anhydride and subsequent reaction of the resulting intermediate with sulfonoketenimides generated in situ from alkynes and sulfonyl azides.
ChemInform Abstract: Facile One‐Pot Synthesis of Tetrahydroisoquinolines from Amino Acids via Hypochlorite‐Mediated Decarboxylation and Pictet—Spengler Condensation.
Authors: Maresh Justin J. , Crowe Sean O. , Ralko Arthur A. , Aparece Mark D. , Murphy Casey M. , Krzeszowiec Mark , Mullowney Michael W.
Published: January 2015

Oxidative decarboxylation of α‐amino acids provides the corresponding aldehydes which are converted into tetrahydroquinolines by addition of dopamine via Pictet—Spengler reaction.
ChemInform Abstract: Unique Regioselectivity in the C(sp3)—H α‐Alkylation of Amines: The Benzoxazole Moiety as a Removable Directing Group.
Authors: Lahm Guenther , Opatz Till
Published: January 2015

The benzoxazol‐2‐yl substituent is easily introduced by oxidative coupling or nucleophilic substitution and can be removed by hydroxide or by hydride reduction.
ChemInform Abstract: Polyvinylpolypyrrolidone‐Supported Boron Trifluoride: A Mild and Efficient Catalyst for the Synthesis of 1,8‐Dioxooctahydroxanthenes and 1,8‐Dioxodecahydroacridines
Authors: Mokhtary Masoud , Mirfarjood Langroudi Seyed Abdollah
Published: January 2015

via simple multicomponent reactions
ChemInform Abstract: Synthesis of Polyfluoroalkyl Aza‐Polycyclic Aromatic Hydrocarbons Enabled by Addition of Perfluoroalkyl Radicals onto Vinyl Azides.
Authors: Wang Yi‐Feng , Lonca Geoffroy Herve , Le Runigo Maiwenn , Chiba Shunsuke
Published: January 2015

Oxidative radical perfluoromethylation of biarylvinyl azides generates iminyl radicals, which subsequently cyclize to produce various aza‐polycyclic aromatic compounds.
ChemInform Abstract: Acid‐Induced Rearrangement of Cycloadducts from N‐Aryl Itaconimides and 1,3‐Diphenylisobenzofuran.
Authors: Stepakov Alexander V. , Boitsov Vitaly M. , Larina Anna G. , Molchanov Alexander P.
Published: January 2015

Diels—Alder adducts generated from imides (I) and benzofuran (II) undergo MesOH mediated rearrangement to form benzoisoquinolinediones.
ChemInform Abstract: Synthesis and Fluorescence Properties of Benzoxazole‐1,4‐dihydropyridine Dyads Achieved by a Multicomponent Reaction.
Authors: Affeldt Ricardo Ferreira , de Amorim Borges Antonio Cesar , Russowsky Dennis , Rodembusch Fabiano Severo
Published: January 2015

Three novel fluorescent compounds (VII), (IX), and (X) are obtained by multicomponent one‐pot Hantzsch reaction of fluorescent aldehyde (V), 1,3‐dicarbonyl compound, and ammonium acetate.
ChemInform Abstract: Facile Synthesis of Imidazo[1,2‐a]pyridines via a One‐Pot Three‐Component Reaction under Solvent‐Free Mechanochemical Ball‐Milling Conditions.
Authors: Maleki Ali , Javanshir Shahrzad , Naimabadi Maryam
Published: January 2015

The advantages of this new method are high yields, mild conditions, short reaction times, high atom‐economy, and easy work‐up.
ChemInform Abstract: Synthesis of Oxadiazolo‐, Pyrimido‐, Imidazolo‐, and Benzimidazolo‐Containing Derivatives of 1,4‐Benzodiazepin‐5‐(4′‐methylpiperazinyl)‐carboxamide Through Phenylamino Spacer.
Authors: Kaur Navjeet , Kishore Dharma
Published: January 2015

All the synthesized compounds show antibacterial and antifungal activities.
ChemInform Abstract: Efficient Synthesis of Eight‐Membered Nitrogen Heterocycles from O‐Propargylic Oximes by Rhodium‐Catalyzed Cascade Reactions.
Authors: Nakamura Itaru , Sato Yoshinori , Takeda Keisuke , Terada Masahiro
Published: January 2015

A series of azocine‐1‐oxides (II) is prepared by a Rh‐catalyzed 2,3‐rearrangement/heterocyclization reaction sequence of corresponding O‐propargylic oximes (I).
ChemInform Abstract: Catalytic Borylation of SCF3‐Functionalized Arenes by Rhodium(I) Boryl Complexes: Regioselective C—H Activation at the ortho‐Position.
Authors: Kallaene Sabrina I. , Braun Thomas
Published: January 2015

Borylation of arenes (I) in the presence of a rhodium catalyst (RHB) proceeds under mild conditions with a unique regioselectivity for the position ortho to the SCF3 group to give monoborylated products (III).
ChemInform Abstract: Copper‐Promoted Oxidative‐Fluorination of Arylphosphine under Mild Conditions.
Authors: Liu Na , Mao Liu‐Liang , Yang Bin , Yang Shang‐Dong
Published: January 2015

In the title reaction, DDQ serves as the oxidizing reagent as well as the hydrogen acceptor.
ChemInform Abstract: Hyalachelins A—C, Unusual Siderophores Isolated from the Terrestrial Myxobacterium Hyalangium minutum.
Authors: Nadmid Suvd , Plaza Alberto , Lauro Gianluigi , Garcia Ronald , Bifulco Giuseppe , Mueller Rolf
Published: January 2015

isolation, structure determination and iron chelating activities
ChemInform Abstract: Regiospecific Synthesis of 2‐Halo‐3‐(2′‐glucalyl)benzo[b]thiophenes.
Authors: Kinfe Henok H. , Makolo Felix L. , Adokoh Christian K.
Published: January 2015

Aryl‐S‐glucosides react with chloroform or bromoform via a carbene insertion and a sigmatropic rearrangement to give novel 2‐halo‐3‐glucalyl substituted benzo[b]thiophenes.
ChemInform Abstract: Catalytic Asymmetric Assembly of C3‐Monosubstituted Chiral Carbazolones and Concise Formal Synthesis of (‐)‐Aspidofractinine: Application of Enantioselective Pd‐Catalyzed Decarboxylative Protonation of Carbazolones.
Authors: Zhao Ruirui , Sun Zhongwen , Mo Mingjie , Peng Fangzhi , Shao Zhihui
Published: January 2015

The first catalytic enantioselective formal synthesis of (‐)‐aspidofractinine (II) is achieved via key intermediate (I), which is synthesized in only ten steps from commercially available starting materials.
ChemInform Abstract: Asymmetric Synthesis and Biological Evaluation of 1,3‐ and 1,4‐Disubstituted Benzo‐Type Lipoxin A4 Analogues.
Authors: Haberlin Gavin G. , McCarthy Ciara , Doran Robert , Loscher Christine E. , Guiry Patrick J.
Published: January 2015

The effect of the eight lipoxin A4 analogues (I) and (II) on cytokines is evaluated with (Ic) and (IId) showing a significant reduction in the production of specific pro‐inflammatory cytokines.
ChemInform Abstract: Hopeachinols E—K, Novel Oligostilbenoids from the Stem Bark of Hopea chinensis.
Authors: Cheng Yi‐Qing , Jiang Rong , Huang Wei , Wei Wei , Chen Chao‐Jun , Tan Ren‐Xiang , Ge Hui‐Ming
Published: January 2015

isolation, structure elucidation, and cytotoxicity of five new stilbenolignans, hopeachinols E—I (I)—(III), and two new stilbenoids, hopeachinols J (IVa) and K (IVb)
ChemInform Abstract: Domino Recombinant γ‐Isomerization and Reverse Wacker Oxidation of γ‐Vinyl‐γ‐butyrolactone: Synthesis of (+)‐trans‐, (‐)‐ and (+)‐Disparlures.
Authors: Bethi Venkati , Kattanguru Pullaiah , Fernandes Rodney A.
Published: January 2015

Title compounds (+)‐trans‐disparlure (I), (+)‐disparlure (II), and the (‐)‐enantiomer of the latter are synthesized from a γ‐vinyl‐γ‐butyrolactone derivative precursor.
ChemInform Abstract: Novel Synthesis of Right Segment of Solanoeclepin A.
Authors: Chuang Hsiang‐Yu , Isobe Minoru
Published: January 2015

The highly strained tricyclo[5.2.1.01,6]decene core (I) of solanoeclepin A is synthesized through two key carbon‐carbon bond forming processes.
ChemInform Abstract: Enantioselective Synthesis of (R)‐Sumanirole Using Organocatalytic Asymmetric Aziridination of an α,β‐Unsaturated Aldehyde.
Authors: Nemoto Tetsuhiro , Hayashi Minami , Xu Dashuang , Hamajima Akinari , Hamada Yasumasa
Published: January 2015

Target compound (IV) is synthesized in 35.8% overall yield and 97% e.e.
ChemInform Abstract: Nanoparticle Conversion Chemistry: Kirkendall Effect, Galvanic Exchange, and Anion Exchange
Authors: Anderson Bryan D. , Tracy Joseph B.
Published: January 2015

Review: 250 refs.
ChemInform Abstract: Polyoxometalate‐ionic Liquids (POM‐ILs)‐the Ultimate Soft Polyoxometalates? A Critical Perspective
Authors: Herrmann Sven , Seliverstov Andrey , Streb Carsten
Published: January 2015

Review: 60 refs.
ChemInform Abstract: Phosphine Complexes of Lone Pair Bearing Lewis Acceptors
Authors: Chitnis Saurabh S. , Burford Neil
Published: January 2015

Review: 82 refs.
ChemInform Abstract: Synthesis, Characterization and Dynamic Behavior of Some Iridium Carbonyl Cluster Complexes Derived from Ir4(CO)12 with N‐, P‐ and C‐Donor Ligands: A Survey
Authors: Tassan Augusto , Mozzon Mirto , Facchin Giacomo , Dolmella Alessandro , Detti Serena
Published: January 2015

Review: 64 refs.
ChemInform Abstract: Recent Mechanistic Developments and Next Generation Catalysts for the Sonogashira Coupling Reaction
Authors: Karak Milandip , Barbosa Luiz C. A. , Hargaden Grainne C.
Published: January 2015

Review: 164 refs.
ChemInform Abstract: What Do We Know about Multicomponent Reactions? Mechanisms and Trends for the Biginelli, Hantzsch, Mannich, Passerini and Ugi MCRs
Authors: Alvim Haline G. O. , da Silva Junior Eufranio N. , Neto Brenno A. D.
Published: January 2015

Review: 50 refs.
ChemInform Abstract: Nano‐Rings with a Handle — Synthesis of Substituted Cycloparaphenylenes
Authors: Tran‐Van Anne‐Florence , Wegner Hermann A.
Published: January 2015

Review: 62 refs.
ChemInform Abstract: Green Chemistry Principles in Organic Compound Synthesis and Analysis
Authors: Verma Ruchi , Kumar Lalit , Kurba Vijay Bhaskar
Published: January 2015

Review: 13 refs.
ChemInform Abstract: Application of Microwave Irradiation in the Synthesis of Fused Six‐Membered Heterocycles with N‐Heteroatom
Authors: Kaur Navjeet
Published: January 2015

Review: 91 refs.
ChemInform Abstract: Stimuli‐responsive Cooperative Catalysts Based on Dynamic Conformational Changes Toward Spatiotemporal Control of Chemical Reactions
Authors: Imahori Tatsushi , Kurihara Seiji
Published: January 2015

Review: [33 refs.
ChemInform Abstract: Novel Synthesis of β‐Lactams and Their Biological Evaluation
Authors: Banik Bimal K.
Published: January 2015

Review: [61 refs.