bluuebunny/crossref_metadata_2025 huggingface dataset:
ASPECTOS DEMOGRÁFICOS E SOCIAIS DE UMA IRMANDADE DE PARDOS: OS FREGUESES DA IGREJA DE SÃO GONÇALO GARCIA
Authors: Lessa Andrea , A. Chá Chá João Gustavo , B. Tavares Reinaldo , Campos Guadalupe do N.
Published: February 2024

Igrejas e irmandades dedicadas a santos pardos instaladas no Rio de Janeiro vem recebendo pouca atenção por parte dos pesquisadores tanto no que se refere ao perfil demográfico dos irmãos quanto a uma melhor compreensão do seu papel religioso e social nos períodos colonial e imperial. Esta era a situação observada para os fregueses da igreja de São Gonçalo Garcia, agravada pela ausência do seu estatuto Compromissal. A análise dos 556 registros de óbito da freguesia do Santíssimo Sacramento, no entanto, possibilitou o conhecimento de vários aspectos sobre a sua identidade, sendo um ponto relevante o fato de formarem um coletivo bastante diversificado, revelando um compromisso pouco rígido quanto às regras de ingresso na irmandade. Verificou-se, ainda, a estreita relação entre os assuntos da fé e da sociabilidade com a ordenação e ocupação de um espaço então desabitado, desvalorizado e insalubre.
Relations between Keynes's theory and F. D. Roosevelt's economic policy in the environment of the Great Economic Depression of 1929 - 1933
Authors: Rogowska Beata
Published: February 2024

Purpose of the study: The aim of the article is to show possible relations between economic theory and economic policy using the example of the interactions between the Great Economic Crisis, Keynes' theory, and Roosevelt's economic policy.

Methodology: The methods used include literature studies and critical analysis of the literature, which are important for the development of a given scientific discipline. The subject of research determines the need to use the historical method. In addition, induction and deduction were used, as well as analysis and synthesis.

Main Findings: Roosevelt's New Deal program is not a perfect reflection of Keynes's theory. In economic policy, such a model approach seems impossible. Both solutions occur parallel to each other. There are points of great similarity, but there are also visible differences. Adopting the thesis about Roosevelt's independence points to the weakness of orthodox economic theory in the face of economic challenges.

Applications of the study: importance in the teaching of economic sciences. The teaching of economic sciences plays a key role in shaping the direction and level of economic knowledge in society. Currently, in addition to economic orthodoxy, a heterodox approach plays an important role in this respect. Therefore, it constitutes the basis for independent analysis in this area. The way of presenting issues within the so-called theoretical subjects, such as the history of economic thought,. For a critical analysis of economic phenomena, it seems important to enrich economic theory with pragmatic aspects. The article aims to interest economics students in the relationship between economic theory and economic practice.

Novelty/Originality of the study: In the context of economic, financial and pandemic crises, considerations regarding the role and importance of economic theory and the scientific discipline itself are important. This is an attempt to answer the question to what extent the achievements of scientists in the field of economics allow us to effectively "get out of the crisis" and to what extent these are ad hoc actions. This is particularly important in the context of changing economic methodology and the relationship between heterodoxy and orthodoxy and the economy in times of uncertainty.
The COVID-19 Tweets Classification Based on Recurrent Neural Network
Authors: Laksito Arif Dwi , Wiranda Nuruddin , Karimah Shofiyati Nur , Hayaty Mardhiya
Published: February 2024

Due to its extensive use in both public and commercial contexts, sentiment analysis on Twitter has recently received much attention, particularly concerning tweets about COVID-19. Information about COVID-19 has been widely spread over social media, resulting in various views, opinions, and emotions about this pandemic, significantly impacting people's health. It is exceedingly challenging for the authorities to find these rumors on these public platforms manually. This paper proposes a framework for text classification using the RNN model and its updates, such as LSTM, BiLSTM, and GRU. This study aims to determine the best recurrent network model for handling cases of Twitter data classification. We utilized Twitter data relevant to COVID-19 and the lockdown with four classification classes (sad, joy, fear, and anger). In addition, this study aims to prove whether GloVe pre-trained word embedding can increase the accuracy of model predictions. The training and testing datasets were split into 80% and 20%, respectively. Therefore, in this experiment an early stopping technique was used with a limit of 15 epochs and a minimum delta of 0.01, meaning that training will be stopped if there is no improvement of 0.1% accuracy after 15 epochs. We used the f1-score average to measure the accuracy of the classification task results. The test results show that the BiLSTM model with GloVe word embedding yields the best f1-score compared to other models. Moreover, in all model testing, the f1-score value of the 'fear' class displays the highest accuracy compared to other classes.
Relación entre el sentido de la vida, la ansiedad, la depresión y el estrés en adultos
Authors: Fonte Carla , Sá Daniela , Pimentão Cristina
Published: February 2024

El significado de la vida ha sido un constructo que ha recibido la atención de investigadores en ciencias psicológicas, quienes han buscado profundizar en el conocimiento de su importancia para la salud mental. En este contexto, se desarrolló un estudio con el objetivo de contribuir al conocimiento científico de este dominio. En concreto, se intentó analizar la relación entre el sentido de la vida y la ansiedad, la depresión y el estrés. Participaron 471 adultos, con edades comprendidas entre los 18 y los 86 años. La recolección de datos se realizó mediante un Cuestionario Sociodemográfico, el Cuestionario de Sentido de Vida y la Escala de Ansiedad, Depresión y Estrés. Los resultados indicaron que los individuos con alta presencia de significado tenían niveles más bajos de depresión, ansiedad y estrés, y que los individuos con un alto nivel de búsqueda de significado tenían niveles más altos de ansiedad, depresión y estrés.
Narrativas de la memoria: el conflicto armado en las producciones audiovisuales colombianas
Authors: Rueda Barrios Olga Beatriz , Acevedo Tarazona Alvaro , Peña López Laura Fernanda
Published: February 2024

El presente artículo ofrece un análisis de las producciones audiovisuales en Colombia para narrar la memoria del conflicto armado. Para ello, se recurre a un enfoque metodológico mixto, con la técnica del análisis de contenido aplicada a diecisiete unidades de análisis, a través de categorías como trama, explicación argumental, tropos, ideologías, hechos victimizantes, actores del conflicto y tipos de violencia. Los resultados permiten establecer que la tragedia prevalece en el discurso narrativo del cine para relatar la violencia vivida, que se convierte en una apuesta simbólica como una forma de reconstrucción de la memoria que podría transitar hacia una memoria poética como escenario de reparación.
Propiedades psicométricas de los cuestionarios de frecuencia y autoeficacia de la regulación emocional en México
Authors: López Tello Alejandro , Goldin Philippe , Moreno Coutiño Ana Beatriz
Published: February 2024

Objetivo. Investigar las propiedades psicométricas de los cuestionarios de Regulación Emocional Frecuencia (ERQ-FR) y Autoeficacia (ERQ-SE) en una muestra mexicana. Método. Se realizó un estudio exploratorio no experimental, ex post facto, en el que participaron 471 adultos. Resultados. El análisis de consistencia interna de ambas escalas mostró una confiabilidad adecuada (ERQ-FR α =.71; y ERQ-SE α =.87). El análisis factorial exploratorio mostró dos factores que explicaban el 56,0 % de la varianza en el ERQ-FR y el 62,4 % de la varianza en el ERQ-SE. El análisis factorial confirmatorio mostró índices de ajuste aceptables y confirmó una estructura de dos factores para cada escala; el factor uno se denominó reevaluación cognitiva y el factor dos, supresión expresiva. Conclusión. Ambos cuestionarios son instrumentos para evaluar la frecuencia de uso y la habilidad percibida para implementar la reevaluación cognitiva y la supresión expresiva como estrategias de regulación de la emoción en población mexicana.
Aproximación general a la gestión por procesos en los servicios de salud en Latinoamérica: una revisión bibliográfica
Authors: Solarte Portilla Ana Lucia , Andrade Sanchez Katalina , Arteaga Diaz Yurany Marilyn , Herrera López Harvey Mauricio
Published: February 2024

El mejoramiento de los servicios de salud o sanitarios ha sido configurado, históricamente, desde diversas estrategias; en este sentido, el enfoque por procesos ha representado una metodología relevante utilizada por las Instituciones Prestadoras de Salud (IPS) para las actividades administrativas y asistenciales. Sin embargo, a la fecha, falta mayor claridad frente a su utilización e impacto en Latinoamérica. El objetivo del artículo es identificar el estado actual de la producción bibliográfica relacionada con la gestión por procesos en los servicios de salud en Latinoamérica, a partir de la revisión de artículos publicados en tres bases de datos (SciELO, PubMed Central y Scopus). Esta revisión bibliográfica se realizó utilizando la metodología PRISMA-P, en la que se definieron criterios de inclusión y exclusión para la recolección, sistematización, selección y análisis de los estudios. Finalmente, se revisaron en profundidad 29 artículos. Los resultados resaltan la caracterización de la gestión por procesos, su implementación en hospitales y la evaluación de los mismos. Los estudios son escasos y el aporte al cuerpo teórico es limitado. En esta región, la gestión por procesos ha avanzado especialmente en lo metodológico y normativo, no obstante, se sugiere avanzar en la implementación de softwares, el empoderamiento del talento humano y en metodologías cuantitativas.
Preliminary Notes on the Extended Heart Sutra in Chinese
Authors: Attwood Jayarava
Published: February 2024

This article offers an introductory overview of the attribution and dating of the versions of the extended Heart Sutra preserved in the Chinese Tripiṭaka and some preliminary assessment of the reliability of these sources. It includes some observations about the interesting features of each version and a stemma showing how they relate to the wider world of Heart Sutra versions. Finally, a conjecture is made about the language in which the extension was made. The Heart Sutra appears to have been extended twice in the early eighth century, leaving us with two different versions of the extended text. It appears that the first extended text, like the standard Heart Sutra, may have been composed in Chinese, while the second extended text appears to have been composed in Sanskrit.
Unveiling the Tapestry of Chinese Wine Consumers: A Quantitative Investigation of Influencing Factors and Consumer Segmentation
Authors: Stöckl Albert
Published: February 2024

Purpose: This study investigates the key influencing factors of wine purchasing behaviour of the Chinese wine consumer market and explores the relevant parameters influencing cluster building among Chinese wine buyers. Design: The data for this study was obtained through a survey distributed to wine company followers from the Changyu Pioneer Wine Co. Inc., on WeChat resulting in the collection and analysis of 1,535 useable valid responses. Findings: Six clusters are identifiable; they differ significantly with various individual characteristics and wine purchasing behaviour. The choice between foreign and domestic wine is a significant factor in understanding wine preferences. The importance of wine attributes (colour, taste, and distribution channels) varied among different groups, indicating that these factors operate differently across populations. Variables pertaining to having experience abroad distinguished and separated younger cohorts. Participants from metropolitan areas, female participants, and younger age groups provided valuable insights into the preferences of the younger generation. Practical implications: Our findings emphasize the importance of considering factors beyond initial wine brand and individual characteristics when studying wine consumer behaviour. Elements such as taste preferences, distribution channels, cultural influences, and personal experiences play a substantial role in shaping wine preferences. Understanding the impact of these factors enables the development of strategies and offerings that better align with the diverse needs and preferences of Chinese wine consumers.
Laporan Kasus: Studi Morfopatologi Demam Babi Afrika pada Babi di Bogor, Jawa Barat
Authors: Wiranti Rahayu Woro , Rahmiati Dwi Utari , Wuriyantara Aldo Yanuar , Poetri Okti Nadia , Handharyani Ekowati
Published: February 2024

Demam Babi Afrika atau African swine fever (ASF) adalah penyakit menular yang dapat terjadi pada ternak babi dan babi liar.Penyakit tersebut disebabkan oleh virus ASF.Gejala klinis sangat bervariasi dari kasus yang terjadi perakut, akut, subakut dan kronis tergantung pada virulensi virus.Kejadian ASF dapat menyebabkan angka kematian tinggi pada babi, penurunan kondisi sosial, dan ekonomi termasuk kontaminasi lingkungan. Berdasar beberapa pertimbangan masalah tersebut, maka akan sangat bermakna bila dilakukan studi morfopatologi dan klarifikasi terhadap kejadian ASF pada babi (Sus scrofa domesticus). Kajian saat ini dilaksanakan dengan melakukan prosedur nekropsi terhadap dua ekor babi umur empat bulan, yaitu dengan melakukan pemeriksaan kondisi tubuh dan organ-organ interna.Sampel organ diambil untuk pemeriksaan histopatologi yang selanjutnya diwarnai dengan hematoksilin-eosin (HE). Pemeriksaan lanjut dilakukan dengan metode polymerase chain reaction (PCR) menggunakan primer universal (p72 dan p54). Hasil pemeriksaan makroskopik menunjukkan bahwa beberapa bagian kulit mengalami erythema, terjadi splenitis hemoragi, enteritis hemoragi disertai dengan lymphadenopathy pada limfonodus mesenterika dan terjadi hemoragi pada meningen dan pembuluh darah di otak. Hasil pemeriksaan histopatologi menunjukkan lesi pada organ limforetikuler seperti limpa dan limfonodus mesenterika, yaitu radang limfositik disertai hemoragi. Pemeriksaan pada otak menunjukkan lesi radang limfositik disertai hemoragi pada selaput meningen. Hasil pemeriksaan molekuler dengan metode PCR memberikan konfirmasi bahwa penyakit disebabkan oleh virus ASF. Berdasarkan hasil pemeriksaan komprehensif secara makroskopik, mikroskopik dan evaluasi PCR dapat disimpulkan bahwa kedua ekor babi tersebut menderita infeksi ASF tipe akut.
Análise bibliométrica da temática objetivos de desenvolvimento sustentável (ODS) no campo das ciências sociais aplicadas
Authors: Lima Anderson Antônio , Ribeiro Thiago de Luca Santana
Published: February 2024

Apesar da relevância da temática e dos impactos dos objetivos de desenvolvimento sustentável em todas as nações, a literatura não apresenta elementos que possibilitem identificar como o fluxo de pesquisa evoluiu ao longo do tempo, entender a evolução das pesquisas sobre a temática podem gerar novos insights e fornecer novas maneiras de implantar objetivos de desenvolvimento sustentável, neste sentido este estudo trata-se de uma análise bibliométrica que visa identificar como o domínio de conhecimento sobre objetivos de desenvolvimento sustentável surgiu e evoluiu no campo de ciências sociais. Trata-se de um estudo revisional, elaborado por meio de uma análise bibliométrica, esta técnica permite o mapeamento do surgimento e evolução de um campo científico, inclusive possibilita identificar os autores mais citados/influentes, instituições dos autores, redes de cooperação entre autores, recorrência de palavras chaves e estudos fronteiriços sobre um determinado tema (Zupic & Cater, 2015). A análise bibliométrica realizada possibilitou identificar por meio do mapa de cocitação a estrutura intelectual que norteia a evolução dos estudos sobre objetivos de desenvolvimento sustentáveis no campo de ciências sociais aplicadas. Esta técnica possibilitou a identificação de sete clusters, o cluster mais importante investigou a interpelação entre os 17 objetivos de desenvolvimento sustentáveis ODS. O mapa de pareamento bibliográfico realizado identificou sete clusters de estudos sobre responsabilidade social corporativa no campo de ciências sociais aplicadas.
 
Palavras-Chave: Análise Bibliométrica, Objetivos de Desenvolvimento Sustentável; Ciências Sociais Aplicadas
ENTELEKTÜEL KATMA DEĞER BİLEŞENLERİ KÂRLILIĞI ETKİLER Mİ? BANKACILIK SEKTÖRÜ ÜZERİNDE BİR ARAŞTIRMA
Authors: KUTBAY Aysegul
Published: February 2024

Bu araştırmada, Borsa İstanbul mali sektörde faaliyet gösteren bankaların entelektüel sermaye bileşenleri ile firma performansları arasındaki ilişkilerin ortaya konulması amaçlanmıştır. Araştırma kapsamında, 2008-2021 tarihleri arasında pay senetleri borsaya kote olmuş ve araştırmanın yapıldığı 2022 yılı itibariyle verilerine eksiksiz bir şekilde ulaşılan bankaların verileri analiz edilmiştir. Entelektüel sermeye bileşenleri, Ståhle, Ståhle ve Aho’nun çalışmasında kullanılan yöntem kullanılarak hesaplama yapılmıştır. Veri seti panel veri olarak hazırlanmış ve STATA 13 paket programıyla analiz edilmiştir. Araştırma kapsamında altı model geliştirilmiş ve test edilmiştir. Değişkenlerin arasındaki etkileşim araştırılırken, korelasyon ve regresyon analizleri uygulanmıştır. Analiz sonucunda; entelektüel sermaye bileşenlerinden biri olan yapısal sermaye ile aktif kârlılığı arasına bir ilişkisine rastlanmaz iken özkaynak kârlılığı ile negatif ve anlamlı bir ilişkisi olduğu tespit edilmiştir. Entelektüel sermaye bileşenlerinden fiziksel sermayesinin aktif kârlılık ve özkaynak kârlılığını en fazla etkilediği araştırmanın bir diğer önemli bulgudur. Entelektüel sermayenin diğer bileşeni insan sermayesi de aktif kârlılık ve özkaynak kârlılığını anlamlı ve pozitif yönde etkilemektedir.
The emerging Sr2FeMoO6-based electrocatalysts for solid oxide electrochemical cell: synthesis, modulation and applications
Authors: Liao Yuanfeng , Xi Xiuan , Chen Hao , Liu Jianwen , Fu Xian-Zhu , Luo Jing-Li
Published: February 2024

Solid oxide cells (SOCs) are regarded as a promising energy technology due to their large current density, diverse range of fuels, and high energy conversion efficiency. The double perovskite Sr2FeMoO6 (SFM) has attracted considerable attention for SOCs due to its tunable structure with superior performance of high conductivity, excellent thermal stability, and remarkable carbon deposition resistance in a reducing atmosphere. However, the electrocatalytic activity of SFM is considerably lower than that of commercial Ni-based SOC electrodes. A timely summary of the synthesis, modulation, and application of SFM perovskites is of great significance for its further development for SOCs. In this review, the methods employed in the preparation of SFM electrocatalysts are introduced first. Then, the advancements in the application of different SFM-based electrocatalysts in the field of SOCs are reviewed, and the research progress in the in situ exsolution of SFM-based electrocatalysts through ion regulation is assessed. Finally, the future issues associated with SFM-based electrocatalysts are addressed in the realm of electrocatalysis, to advance their application.
Orthopaedic Manifestations of Scurvy in an Otherwise Healthy Child from a Low Opportunity Index Neighborhood
Authors: Falkenberg Alexandra L. , Karkenny Alexa J. , Sharkey Melinda S.
Published: February 2024

Case:

A 23-month-old otherwise healthy female child from a low opportunity index neighborhood presented with 1 month of lower extremity pain and refusal to bear weight. Radiographic evaluation of bilateral knees revealed lucent metaphyseal bands and a nondisplaced distal femoral metaphyseal corner fracture. A workup identified vitamin C deficiency (scurvy), and the child's symptoms and radiographic abnormalities resolved with vitamin C supplementation.

Conclusions:

Scurvy should be considered in children with unexplained musculoskeletal symptoms who may lack access to nutrient-dense foods.
Computationally efficient modeling of lightweight expeditionary airfield surfacing systems at large length scales
Authors: Kinser Ryan , Barkey Mark , Rushing Timothy , Cisko Abby , Garcia Lyan , Allison Paul , Jordon J.
Published: February 2024

Expeditionary airfield matting systems are lightweight, portable surfaces that enable the rapid deployment of infrastructure to support aircraft operations. Individual matting components are assembled via interlocking joints to construct arrays that serve as temporary aircraft operating surfaces. The paper outlines the homogenization of the AM2 portable airfield matting system and its interlocking mechanisms to permit computationally efficient analyses toward understanding mechanisms that influence the global behavior of these arrays and underlying subgrade during aircraft maneuvers. An equivalent orthotropic two-dimensional continuum was developed from finite element analysis of a detailed three-dimensional model and its flexural behavior was validated against experimental data and solid finite element models. Interlocking joints were characterized using node-to-node connector elements based on subscale finite element studies. Both components were implemented into a full-scale model representative of a typical test section, and responses to static high tire pressure aircraft loads were analyzed over a soil foundation representing a California bearing ratio of 6%, yielding promising agreement with experimental data. Results of this study reveal an inherent coupling between load transfer, mat deflection, and near-surface subgrade stress with dependence on tire location, mat core shear flexibility, and joint stiffness.
Hércules Musarum: poética e patronagem no encerramento dos Fastos de Ovídio
Authors: Serignolli Lya
Published: February 2024

No encerramento dos Fastos (6.797-812), Ovídio descreve um encontro com Hércules e as Musas, deusas da poesia, às quais pede ajuda para encerrar sua obra sobre o calendário romano. A cena epifânica se passa no templo de Hércules das Musas (aedes Herculis Musarum), onde o poeta dialoga com uma das Musas, Clio, que se refere ao local como o monumento de Filipo (monimenta Philippi). No Período Augustano, Lúcio Márcio Filipo, parente próximo de Augusto, foi responsável pela restauração desse templo, dedicado por Marco Fúlvio Nobílior em 179 a.C.. A Musa dedica louvores a Filipo e sua família, empregando uma linguagem elaborada e alusiva, que gera ambiguidades e leva a questionamentos quanto à natureza desse encômio político. Como veremos, Hércules e as Musas raramente figuram juntos e essa associação incomum pode ser observada em conexão com questões de poética e patronagem em Roma. Este artigo investiga os papéis de Hércules e das Musas na articulação do programa poético dos Fastos, bem como na perpetuação da memória por meio da poesia, considerando-se as relações de patronagem poética entre Ovídio e o centro do poder em Roma.
WITHDRAWN: Causal relationship between immune cells and idiopathic pulmonary fibrosis based on Mendelian randomization analysis
Authors: Gong peng , Lu yimin , Li man , Li xiaobo , Carla Cristina Janjacomo
Published: February 2024

The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference.
Longitudinal trajectories of immunometabolic marker in various mental disorders and their relationship with brain structures
Authors: Cheng Wei , Yujia Wang , You Jia , Li Yuzhu , Kang Jujiao , Yu Jin-Tai , Feng Jianfeng , Wang Linbo
Published: February 2024

Background:
Studies have identified immunometabolic biomarkers for various mental disorders, but their temporal evolution and relationship with brain structure remain unclear. This study aimed to assess the long-term trajectories of immunometabolic biomarkers across 10 years leading up to and following diagnosis and explore their association with brain structure.
Methods:
We conducted a nested case-control study using prospective community-based cohort data from UK Biobank, which included both psychiatric assessments and immunometabolic markers. Cases were defined as individuals with a diagnosis of mental disorders at baseline and during follow-up. Nearly 5 controls without any mental disorders were matched for each case. Multivariable linear regression was used to assess the divergence evolution between cases and controls for each psychiatric assessment and immunometabolic biomarker.
Results:
In comparison to controls, 6, 15, 10, and 47 immunometabolic markers exhibited significant changes over time in bipolar disorder, anxiety, schizophrenia, and depression, respectively. These biomarkers could be grouped into distinct clusters with complex, non-linear trajectories. Some clusters displayed monotonic changes, while others reversed near the time of diagnosis. The identified immunometabolic markers were associated with brain structure in the general population, including orbitofrontal, precuneus, and amygdala regions.
Conclusions:
These findings provide novel insights into the temporal dynamics of immunometabolic biomarkers in various mental disorders within 10 years before and after clinical diagnosis, as well as their correlation with brain structure. Monitoring and managing these biomarkers could potentially carry significant implications for the early detection and prevention of mental disorders in older adults.
Double Difficulties, Defense in depth A succinct authenticated key agreement protocol
Authors: Hsieh WenBin
Published: February 2024

In 2016, NIST announced an open competition with the goal of finding and standardizing a suitable quantum-resistant cryptographic algorithm, with the standard to be drafted in 2023. These algorithms aim to implement post-quantum secure key encapsulation mechanism (KEM) and digital signatures. However, the proposed algorithm does not consider authentication and is vulnerable to attacks such as man-in-the-middle. In this paper, we propose an authenticated key exchange algorithm to solve the above problems and improve its usability. The proposed algorithm combines learning with errors (LWE) and elliptic curve discrete logarithm problem to provide the required security goals. As forward security is a desirable property in a key exchange protocol, an ephemeral key pair is designed that a long-term secret compromise does not affect the security of past session keys. Moreover, the exchange steps required by the algorithm are very streamlined and can be completed with only two handshakes. We also use the random oracle model to prove the correctness and the security of proposed scheme. The performance analysis demonstrates the effectiveness of the proposed scheme. We believe that the novel approach introduced in this algorithm opens several doors for innovative applications of digital signatures in KEMs.
Frequency-hopping along with Resolution-turning for Fast and Enhanced Reconstruction in Ultrasound Tomography
Authors: Quang-Huy Tran , Sharma Bhisham , Theu Luong Thi , Tran Duc-Tan , Chowdhury Subrata , Karthik Chandran , Gurusamy Saravanakumar
Published: February 2024

The distorted Born iterative (DBI) method is considered to obtain images with high-contrast and resolution. Besides satisfying the Born approximation condition, the frequency-hopping (FH) technique is necessary to gradually update the sound contrast from the first iteration and progress to the actual sound contrast of the imaged object in subsequent iterations. Inspired by the fact that the higher the frequency, the higher the resolution. Because low-frequency allows for low-resolution object imaging, hence for high-resolution imaging requirements, using low-frequency to possess a high-resolution image from the first iteration will be less efficient. For an effective reconstruction, the object's resolution at low frequencies should be small. And similarly, with high frequencies, the object resolution should be larger. Therefore, in this paper, the FH, and the resolution-turning (RT) technique are proposed to obtain object images with high-contrast and -resolution. The convergence speed in the initial iterations is rapidly achieved by utilizing low frequency in the frequency-turning technique and low image resolution in the resolution-turning technique. It is crucial to ensure accurate object reconstruction for subsequent iterations. The desired spatial resolution is attained by employing high frequency and large image resolution. The resolution-turning distorted Born iterative (RT-DBI) and frequency-hopping distorted Born iterative (FH-DBI) solutions are thoroughly investigated to exploit their best performance. This makes sense because if it is not good to choose the number of iterations for the frequency f1 in FH-DBI and for the resolution of N1×N1 in RT-DBI, then these solutions give even worse quality than traditional DBI. After that, the RT-FH-DBI integration was investigated in two sub-solutions. We found that the lower frequency f1 used both before and after the RT would get the best performance. Consequently, compared to the traditional DBI approaches, the normalized error and total runtime for the reconstruction process were dramatically decreased, at 83.6% and 18.6%, respectively. Besides fast and quality imaging, the proposed solution RT-FH-DBI is promised to produce high-contrast and high-resolution object images, aiming at object reconstruction at the biological tissue. The development of 3D imaging and experimental verification will be studied further.
Blend denim fabric performance: Key features of dyed weft silk yarn with different weave structures
Authors: Youssef Yehya , Mousa Abdalla , Kafafy Hany , Hamouda Tamer , El-Ola Samiha Abo
Published: February 2024

This research aimed to weave the warp indigo-dyed cotton yarn with un-dyed or dyed silk yarn and analyze the impact of different weft yarn structures on the properties of denim fabrics. The dyed silk yarn was performed by selection of different anionic indigo and non-indigo blue dyestuffs. The dyeing shades of the anionic indigo carmine dye on silk exhibited high build-up at the acidic pH range 2-2.5 with poor washing fastness and even so the cationic aftertreatment of the dyed silk samples showed un-matched color with indigo dyed cotton yarns. The dyeing properties of two commercial non-indigo reactive and acid dyes on silk add other advantages. To ascertain the dyeing shades of the non-indigo dyes on silk, two sets of blended denim fabrics were investigated. The first set included a weft-wise silk yarn dyed with reactive dye RB 5, and the second set included silk yarns dyed with acid dye AB 193. Weaving of the blended fabrics were carried out in Twill 3/1, 3/2 Z and Satin 53 patterns and exhibited significant color effects of the dyed silk yarns to those of the un-dyed control samples. The dyeing shades of the non-indigo RB 5 and AB 193 dyed weft-wise silk yarns found to be matched in color performance with the conventionally indigo dyed cotton yarns. Ultraviolet resistance of the blend denim fabrics was evaluated, showing significant improve in UPF of the weft-wise dyed silk. The study claimed the dyed silk yarns a good candidate for newly developed blend denim fabrics.
Terphenyllin induces CASP3-dependent apoptosis in A375 cells through upregulation of P53
Authors: Wang Qin , Wu Wei , Wu Yuan , Dai Ting , Ke Na , Shi Yan
Published: February 2024

Melanoma, the deadliest form of skin cancer, can develop in any area where melanocytes are present. Currently, platinum-based chemotherapeutic drugs such as cisplatin are commonly used for anti-tumor treatment. However, these drugs often result in significant cytotoxicity, highlighting the need for more effective and less toxic alternatives. Terphenyllin (TER) is a natural compound derived from the coral fungus Aspergillus candidus. Our results demonstrated that TER notably induces apoptosis while exhibiting lower cytotoxicity than does cisplatin at equivalent doses. We observed an upregulation of P53 expression in A375 cells following TER treatment, accompanied by the cleavage of CASP3, GSDME, and PARP1. Upregulated P53 led to increased expression of FAS/BAX and elevated expression of BAX, which prompted the release of cytochrome c from mitochondria to the cytoplasm, ultimately triggering CASP3 cleavage. By knocking out CASP3, TER-induced GSDME cleavage was alleviated and TER-induced A375 cells were shift from apoptosis to necrosis. Additionally, our investigation of the role of GSDME in TER-induced cell death revealed that knockout of GSDME significantly enhanced TER-induced apoptosis and reduced LDH release during induction. Our study demonstrated that TER promotes apoptosis in A375 cells through the P53-BAX-CASP3 pathway. Furthermore, the upregulation of P53 blocks the cell cycle in S-phase by inhibiting CyclinA2 expression. This dual effect eradicates melanoma cells by promoting apoptosis and inhibiting proliferation simultaneously. In summary, our research provides insights into the molecular mechanisms underlying the action of TER on melanoma cells. These findings may have important implications for the development of novel antimelanoma therapeutics.
A high security coding and anti-counterfeiting method based on the nonlinear magnetization response of superparamagnetic nanomaterials
Authors: shi BAI , lin Yuxi , Wang Xiaoju , Zhang Xiaodan , Yoshida Takashi , Yue Xiaohan
Published: February 2024

Traditional coding methods based on graphics and digital or magnetic labels have gradually decreased their anti-counterfeiting because of market popularity. This paper presents a new anti-counterfeiting coding method. This method uses a high-performance coding material, which, along with small changes to the material itself and the particle size of the magnetic nanomaterials, results in a large difference in the nonlinear magnetization response. This method, which adopts 12-site coding and establishes a screening model by measuring the voltage amplitude of 12-site variables, can code different kinds of products, establishing long-term stable coding and decoding means. Through the anti-counterfeiting experiment of wine, the experiment results show that the authenticity of the coded products can be verified using the self-developed automatic coding and decoding detection system. The new coding technology can verify the anti-counterfeiting of 9,000 products, with a single detection accuracy of 97% and a detection time of less than one minute. Moreover, this coding method completely depends on the production batch of the superparamagnetic nanomaterials, which is difficult to imitate, and it provides a new coding anti-counterfeiting technology for related industries with a wide range of potential applications.
An Advanced Fast Method for The Evaluation Of Multiple Immunolabelling Using Gold Nanoparticles Based On Low-Energy STEM.
Authors: Kitzberger František , Yang Shun-Min , Týč Jiří , Bílý Tomáš , Nebesářová Jana
Published: February 2024

We present a powerful method for the simultaneous detection of Au nanoparticles located on both sides of ultrathin sections. The method employs a high-resolution scanning electron microscope (HRSEM) operating in scanning transmission electron microscopy (STEM) mode in combination with the detection of backscattered electrons (BSE). The images are recorded simultaneously during STEM and BSE imaging at the precisely selected accelerating voltage. Under proper imaging conditions, the positions of Au nanoparticles on the top or bottom sides can be clearly differentiated, hence showing this method to be suitable for multiple immunolabelling using Au nanoparticles (NPs) as markers. The difference between the upper and lower Au NPs is so large that it is possible to apply common software tools (such as ImageJ) to enable their automatic differentiation. The effects of the section thickness, detector settings and accelerating voltage on the resulting image are shown. Our experimental results correspond to the results modeled in silico by Monte Carlo simulations.
Convergent evolution on oceanic islands: comparative genomics reveals species-specific processes in birds
Authors: Recuerda María , Montoya Julio César Hernández , Blanco Guillermo , Milá Borja
Published: February 2024

Understanding the factors driving phenotypic and genomic differentiation of insular populations is of major interest to gain insight into the speciation process. Comparing patterns across different insular taxa subjected to similar selective pressures upon colonizing oceanic islands provides the opportunity to study parallel evolution and identify shared patterns in their genomic landscapes of differentiation. We selected four species of passerine birds (common chaffinch Fringilla coelebs/canariensis, red-billed chough Pyrrhocorax pyrrhocorax, house finch Haemorhous mexicanus and dark-eyed/island junco Junco hyemalis/insularis) that have both mainland and insular populations. For each species, we sequenced whole genomes from mainland and insular individuals to infer their demographic history, characterize their genomic differentiation, and identify the factors shaping them. We estimated the relative (Fst) and absolute (dxy) differentiation, nucleotide diversity (π), Tajima’s D, gene density and recombination rate. We also searched for selective sweeps and chromosomal inversions along the genome. Changes in body size between island and mainland were consistent with the island rule. All species shared a marked reduction in effective population size (Ne) upon island colonization. We found highly differentiated genomic regions in all four species, suggesting the role of selection in island-mainland differentiation, yet the lack of congruence in the location of these regions indicates that each species adapted to insular environments differently. Our results suggest that the genomic mechanisms involved, which include selective sweeps, chromosomal inversions, and historical factors like recurrent selection, differ in each species despite the highly conserved structure of avian genomes and the similar selective factors involved.
Optimizing ETo Prediction in the Mahanadi Basin: A Comprehensive Evaluation of Machine Learning Models with Emphasis on ANFIS Performance
Authors: Raj Deepak Kumar , Gopikrishnan T
Published: February 2024

This study extensively analyzed three models, M5P, ANFIS, and GEP, to predict Actual Evapotranspiration (ETo) in the Mahanadi Basin region on six major stations Raipur, Korba, Jharsuguda, Bilaspur, Bhubaneswar, and Balangir. Evaluation metrics, including R2, RMSE, NSE, and MAE, were applied to a testing dataset, revealing ANFIS's consistent superiority with high R2 (0.930746 to 0.990526) and NSE (0.926792 to 0.990458) values, alongside the lowest RMSE (0.101152 to 0.332819) and MAE (0.000386 to 0.034319). Weighted scores affirmed ANFIS's dominance across multiple stations, except for specific instances where GEP excelled in Bhubaneswar and M5P in Balangir. The study highlighted ANFIS's proficiency in predicting ETo values at specific locations, demonstrated through effective variation capture in scatter plots. The discussion underscored the importance of model selection, emphasizing the versatility of machine learning models and the effectiveness of combining AI techniques for accurate ETo prediction. ANFIS consistently outperformed M5P and GEP, solidifying its status as a reliable ETo prediction tool. While acknowledging M5P and GEP's potential in specific contexts, the study stressed the need to tailor models to unique location characteristics. Reference to related studies supported the effectiveness of hybridized AI approaches in improving ETo modeling. The study advocated ongoing research to refine models, incorporate additional factors, and enhance predictive accuracy. The findings contribute valuable insights for water resource management, irrigation planning, and agricultural decision-making across diverse locations.
Case report: An acute case of oscillopsia
Authors: Fontanelli Lorenzo , Prete Eleonora Del , Migaleddu Gianmichele , Giannini Nicola , Bellini Gabriele , Becattini Lucrezia , Bianchi Francesca , Cosottini Mirco , Siciliano Gabriele
Published: February 2024

Ocular flutter has been associated with a variety of neurologic and systemic diseases but a clear localization of the involved brain structures is missing. This unique case of acute ocular flutter due to a focal ischemia in the right posterior portion of the medulla oblongata, extending also towards the ipsilateral inferior cerebellar peduncle and the olivary body, sheds lights on the anatomical structures involved in the context of the systems related to horizontal gaze fixation.
Oncolytic reovirus enhances the effect of CEA immunotherapy when combined with PD1-PDL1 inhibitor by reducing the immunosuppressive tumor microenvironment in a colorectal cancer model
Authors: Yari Atefeh , Hosseini Seyed Younes , Asiyabi Sanaz , Hajiahmadi Nazila , Farahmand Mohammad , Bamdad Taravat
Published: February 2024

Immunotherapy is a type of tumor treatment that increases anti-tumor immunity to inhibit tumor growth. By enhancing the immune response through the lysis of tumor cells with an oncolytic virus and inhibiting the immune system's inhibitory reactions, the effectiveness of immunotherapy can be improved. In this study on a mouse model of colorectal cancer, the efficacy of oncolytic reovirus in a combined treatment with an adenovector expressing carcinoembryonic antigen (CEA) and PD-1/PD-L1 inhibitor was evaluated. The tumorized mice with CEA-expressing CT26 cells were immunized with a constructed adenovector expressing CEA along with PD-1/PD-L1 inhibitor. Then three doses of reovirus were injected into the tumor. On day of 26th, all mice were sacrificed, and tumor size, histopathological findings, and immune response to tumor antigens were compared among treatment groups. The results showed that immunization with CEA, combined with treatment with reovirus and PD-1/PD-L1 inhibitor, resulted in the lowest tumor growth among the treated groups. Additionally, the combined treatment group exhibited the highest level of cytotoxic immunity. This treatment also led to a decrease in Foxp3 in the tumor microenvironment and TNF-α secretion compared to other groups. Furthermore, through the production of IFN-γ and increased cytotoxic effect, it was demonstrated that the cellular immune system works more efficiently. Histopathological evaluations revealed the lowest number of mitosis and the highest amount of tumor-infiltrating lymphocytes (TILs) in this group. In conclusion, although the combination of tumor vaccines with oncolytic viruses improves treatment efficacy, inhibiting the PD-1/PD-L1 interaction can further enhance immunovirotherapy efficacy by reducing immunosuppressive effects boosted by the virus activity, and stimulating the immune system. This approach, in combination with other treatment methods, shows promise in controlling tumor growth.
The effects of some pesticides used in potato fields on the pre-adult stages of Chelonus oculator F. (Hymenoptera: Braconidae)
Authors: SAÇTI Zühal , ÖZKAN Cem
Published: February 2024

One of the most important pests of potatoes is the Potato Tuber Moth Phthorimaea operculella (Zeller) (Lepidoptera: Gelechiidae) worldwide and one of its new parasitoids is Chelonus oculator (F.) (Hymenoptera: Braconidae). All over the world, chemical control is commonly used in the control of P. operculella. However, the side effects of chemicals on nature and beneficial organisms have become very important nowadays. For this reason, the side effects of selected pesticides, against Potato Tuber Moth, on Chelonus oculator eggs and larvae were tested under laboratory conditions. Three insecticides (Spinetoram, Gamma cyhalothrin, Chlorantraniliprole), one fungicide (Phosphorus Acid), and a biological insecticide (Bacillus thuringiensis var. kurstaki) were applied to parasitized first and third-stage larvae and parasitized eggs. Application dose, half dose, and 1/20 dose of these products were used. All preparations used in the experiments had a highly toxic effect in the pre-adult period. Therefore, the sex ratio could not be determined due to the low number of emerged parasitoids. All doses of applied pesticides caused an increase in the development time of parasitoids developing from parasitized eggs and first larvae when compared to the control. It can be concluded that the development time of parasitoids decreased in 3rd instar larvae. We also evaluated the longevity of parasitoids and it was found that the adult life emerging from parasitized first and third instar potato moth larvae decreased. We also observed that the survival of adult parasitoids emerging from parasitized eggs was unstable. In this study, it was determined that pesticides applied to the parasitized host at different stages affected the adult weight of the parasitoid C. oculator. When the sex ratio of the parasitoid was examined, it was not possible to reach a definite conclusion due to the lack of sufficient individual emergence. The side effect results obtained can be evaluated in integrated control programs for the Potato tuber moth and its parasitoid Chelonus oculator.
Implementation of comprehensive information security model by using JWT & CryptoJS
Authors: Balkhande Yash , Bhamburkar Gayatri , Waghmare Shreyash , Nehare Vedant , Gadicha Vijay
Published: February 2024

Information security refers to the processes and tools specifically designed and deployed to protect sensitive business information from modification, disruption, destruction, and inspection furthermore. An enhanced model of information security can be made by combining various technologies such as JWT (pronoun JSON Web Token) for authentication and authorization, CryptoJS for encrypting, decrypting, and hashing of useful information, and NodeMailer for OTP transmission. Presenting a three-tiered security model to strengthen user authentication, initiated by the conventional username and password combination, establishing a foundational barrier in the first tier. Subsequently, the second tier uses Google CAPTCHA, enhancing security by mitigating automated threats. In the final tier, a one-time password (OTP) is dispatched to the user's registered mobile number or email, adding an extra layer of authentication. This structured methodology reflects our commitment to refining security protocols and preserving sensitive user information within a measured and comprehensive framework. To increase the security we will be using CryptoJS to encrypt and decrypt the message, and we will store our data in encrypted form at the database.