bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental measurements of CO2 adsorption on Indonesian low-rank coals under various conditions
Authors: Tambaria Theodora Noely , Sugai Yuichi , Anggara Ferian
Published: September 2022

In this study, the CO2 adsorption capacity was measured on Indonesian low-rank coals in the raw and dry conditions in powder and block states using different coal sample preparation to estimate CO2 sequestration and storage potential. Coal sample specimens were taken from three different areas in the South Sumatra Basin, Indonesia. The adsorption experiments were performed using the volumetric method at a temperature of 318.15 K and pressure up to 3 MPa. The CO2 excess adsorption capacity of powder coal is always higher than block coal. Moreover, decreasing moisture content by the drying process increases CO2 adsorption capacity on coal. Based on fitted CO2 adsorption experimental data with the Langmuir and Freundlich isotherm model, the adsorption occurs on monolayer and multilayer at various conditions. Langmuir volume capacity and pressure show drying and crushing process increased adsorption capacity. However, the drying process affects more the capability of coal to adsorb CO2 than the powdered sample, especially in low-rank coal. It was also observed adsorption capacity is directly proportional to huminite content in the coal. Due to lower moisture and higher huminite contents, the dried WB coal powder had the highest CO2 adsorption capacity over the other coal samples in similar sample conditions. Altogether, this study may provide a better understanding in CO2 adsorption on low-rank coal with different coal sample preparation resulting in different CO2 adsorption capacity.
Alternative proofs of some classical metric fixed point theorems by using approximate fixed point sequences
Authors: Berinde Vasile , P̆acurar M̆ad̆alina
Published: September 2022

The notion of approximate fixed point sequence, emphasized in Chidume (Geometric properties of Banach spaces and nonlinear iterations. Lecture Notes in Mathematics, 1965. Springer-Verlag London, Ltd., London, 2009), is a very useful tool in proving convergence theorems for fixed point iterative schemes in the class of nonexpansive-type mappings. In the present paper, our aim is to present simple and unified alternative proofs of some classical fixed point theorems emerging from Banach contraction principle, by using a technique based on the concepts of approximate fixed point sequence and graphic contraction.
A Second-Order Closed-Form $$J_2$$ Model for the Draper Semi-Analytical Satellite Theory
Authors: San-Juan Juan F. , López Rosario , Cefola Paul J.
Published: September 2022

A second-order closed-form semi-analytical solution of the main problem of the artificial satellite theory ($$J_2$$

J
2

contribution) consistent with the Draper Semi-analytic Satellite Theory (DSST) is presented. This paper aims to improve the computational speed of the numerical-based approach, which is only available in the GTDS-DSST version. The short-period terms are removed by means of an extension of the Lie-Deprit method using Delaunay variables. The averaged equations of motion are given explicitly and transformed to the non-singular equinoctial elements. Finally, the second-order terms in the equations of motion are included in the C/C++ version of the DSST orbit propagator.
Assessing Consumer Attitude Towards Marine Non-Indigenous Fish Species: A Case Study From Greece (Eastern Mediterranean Sea)
Authors: Minasidis Vasileios , Doumpas Nikolaos , Giovos Ioannis , Kleitou Periklis , Kaminas Alexandros , Moutopoulos Dimitrios K.
Published: September 2022

Non-indigenous fish species (NIFS) are spreading in the Mediterranean Sea, altering species assemblages and reshaping the marine ecosystems. Market-based approach has been promoted as a measure to limit the spread and damages by the NIFS and provide economic revenues to fishers. Understanding drivers of NIFS consumption and documenting consumers’ habits are pivotal in guiding a market strategy. Α custom-made online questionnaire was developed and distributed to Greek consumers through Social Media networks. The majority of consumers: (a) supported that NIFS are causing adverse effects to the marine environment (54%), (b) would consume NIFS products if they encountered them on a restaurant menu (62%), (c) would buy and consume NIFS provided they protect the marine environment and indigenous species (76%), and (d) hanker for the implementation of a quality control certificate on NIFS products (79%). Multivariate models revealed that the most important criteria for the consumers except for taste were the freshness of the products, whether the fish is poisonous, and the hygienic conditions of the fish market and its staff. The results reflected the positive attitude of the Greek consumers towards the consumption of NIFS and highlighted the importance of further promoting a market that could improve fisheries sustainability and challenge non-indigenous species (NIS) proliferation.
Trends in Termination of Pregnancy for Foetal Urological Abnormalities in England and Wales: a Cross-Sectional Study
Authors: Jeffery Megan , Tai-MacArthur Sarah , Shangaris Panicos , Duggan Martin , Spencer Julia , Sankaran Srividhya
Published: September 2022

The detection of developmental abnormalities in the foetus is considered an essential component of antenatal screening. Among the most frequently identified sonographically, and possibly one of the easiest recognised, are those affecting the urinary tract, with an incidence of 1–4 in 1000 pregnancies. As such, foetal urological abnormalities represent up to 30% of all prenatally diagnosed congenital anomalies. We analysed information recorded on the Health and Social Act 4 (HSA4) forms submitted to the Department of Health and Social Care (DHSC) for 2015 to 2019. There were 915 cases of termination of pregnancy for foetal urological anomaly between 2015 and 2019 in England and Wales, representing 0.09% of total abortions. There has been a steady increase in cases, from 186 in 2015 to 222 in 2018, followed by a more recent decline in 2019 to 172. All 915 cases were justified under Ground E of The Abortion Act 1967. Most terminations of pregnancy for foetal urological anomaly were carried out at 20 weeks gestation. Isolated urinary tract single diagnoses were the commonest, with megacystis being the most prevalent, followed by bilateral renal agenesis and bilateral cystic kidneys. Nearly a third of cases (32.2%) were performed in women aged 30–34 years, and almost 4/5 of women (78.7%) were of White ethnicity. Foetal urological abnormality is a complex issue affecting a significant minority of pregnant women. When severe abnormalities are detected by prenatal diagnosis, most women choose to terminate the pregnancy.
Asia Partnership Conference of Pharmaceutical Associations (APAC) Report on Regulatory Agility Implemented During the COVID-19 Pandemic: Inspiring Partnerships and Recommendations for the Way Forward
Authors: Chong Sannie Siaw Foong , Kanno Masaaki , Chee Alice Seat Mee , Long Siew Mei , Ong Stephanie Hui Min , Harnpramukkul Usanee , Binos Richard Simon R.
Published: September 2022

Purpose

Asia Partnership Conference of Pharmaceutical Associations (APAC) promote regulatory agility of four important best practices i.e. reliance, digital platform, accepting electronic document and process integration. Dialogues and strong partnership witnessed reforms and efficiencies amidst the pandemic. In tracking the progress of regulatory agility, APAC identifies areas for improvement and recommends prioritizing these areas for change.

Methods

As one voice, 13 main industry associations under the umbrella of APAC sent joint letters to our National Regulatory Authorities (NRAs) with a call to maintain regulatory agility and consider new ways of working. Consequently, APAC surveyed its member associations to measure regulatory agilities implemented by the NRAs during 2020 and 2021 in view of the pandemic.

Results

This paper reports progress in implementing regulatory agility, e.g. the number of economies that can accept electronic Certificate of Pharmaceutical Products (eCPP) has reached 100% for the economies that require CPP and more than 90% can waive onsite inspection in the presence of Good Manufacturing Practice (GMP) certificate and/or inspection report. The paper also features the progress made in Malaysia, the Philippines, and the ASEAN (Association of South East Asian Nations) regional reliance initiative to reduce inefficiencies and duplications.

Conclusions

We have demonstrated the power of working together to enable regulatory agilities and efficiencies. APAC will continue to track the progress of all economies including India within the areas for improvement prioritized and discussed in this paper. APAC is also committed to working with key stakeholders including our NRAs in Asia to sustain and enable a new era of innovation ushered in by COVID-19 to benefit patients.
DrSim: Similarity Learning for Transcriptional Phenotypic Drug Discovery
Authors: Wei Zhiting , Zhu Sheng , Chen Xiaohan , Zhu Chenyu , Duan Bin , Liu Qi
Published: September 2022

Transcriptional phenotypic drug discovery has achieved great success, and various compound perturbation-based data resources, such as connectivity map (CMap) and library of integrated network-based cellular signatures (LINCS), have been presented. Computational strategies fully mining these resources for phenotypic drug discovery have been proposed. Among them, the fundamental issue is to define the proper similarity between transcriptional profiles. Traditionally, such similarity has been defined in an unsupervised way. However, due to the high dimensionality and the existence of high noise in high-throughput data, similarity defined in the traditional way lacks robustness and has limited performance. To this end, we present DrSim, which is a learning-based framework that automatically infers similarity rather than defining it. We evaluated DrSim on publicly available in vitro and in vivo datasets in drug annotation and repositioning. The results indicated that DrSim outperforms the existing methods. In conclusion, by learning transcriptional similarity, DrSim facilitates the broad utility of high-throughput transcriptional perturbation data for phenotypic drug discovery. The source code and manual of DrSim are available at https://github.com/bm2-lab/DrSim/.
Diabetic foot limb threatening infections: Case series and management review
Authors: Hatem Mohamed Abdulhameed , Kamal Dhafer M. , Yusuf Khalifa Abdulrahman
Published: September 2022

Abstract

Introduction and importance

Limb-threatening infections are among the most serious diabetic foot complications that can rapidly escalate into tissue necrosis. In addition, treatment delays can lead to infection progression within hours, putting the patient at high risk for amputation. Therefore, early disease identification, proper assessment, and aggressive intervention are vital for managing this complication.

Case presentation

The study presents three cases with limb-threatening infections: a 55-year-old diabetic male with chronic renal disease, a 68-year-old diabetic male with hypertension and ischemic heart disease, and a 60-year-old diabetic male.

Clinical discussion

A combination of surgical intervention and antibiotic therapy is vital for limb and patient survival. The surgical treatment consists of drainage of pus and removal of necrotic and infected tissue, with the integration of appropriate systemic metabolic management and a multidisciplinary team approach. Once the infection is controlled, early vascular intervention is performed, followed by debridement of necrotic soft tissues, with or without revision of the amputation stump. Surgery aims to control the infection, preserve patient health, and maintain a functional limb. Thus, the surgeon must understand foot anatomy and compartments and be familiar with wound healing in diabetic patients.

Conclusion

Diabetic foot complications are preventable through a multidisciplinary management team approach. This management approach is effective in improving limb salvage rates. Since the prevalence of diabetic and diabetic foot infection worldwide is increasing, evidence-based guidelines, multidisciplinary teams, and institution-specific clinical processes should be implemented to guide the optimal care of this problem.

Highlights
A Stata Companion for The Fundamentals of Social Research
Authors: Kellstedt Paul M. , Whitten Guy D. , Tuch Steven A.
Published: September 2022

A Stata Companion for The Fundamentals of Social Research offers students the opportunity to delve into the world of Stata using real data sets and statistical analysis techniques directly from Paul M. Kellstedt, Guy D. Whitten, and Steven A. Tuch's new textbook. Workbook sections parallel chapters in the main text, giving students a chance to apply the lessons and techniques learned in each chapter in a statistical software setting. Detailed chapters teach students to reproduce results presented in the textbook, allowing them to become comfortable performing statistical analyses for evaluating causal claims through repeated practice. Step-by-step instructions for using Stata are provided, along with command lines and screenshots to demonstrate proper use of the software. Instructions for producing the figures and tables in the main text are integrated throughout the workbook. End-of-chapter exercises encourage students to formulate and evaluate their own hypotheses.
Modelling and analysis of an endothermic reacting counter-current flow
Authors: Luckins Ellen K. , Oliver James M. , Please Colin P. , Sloman Benjamin M. , Van Gorder Robert A.
Published: September 2022

We study the endothermic reaction and flow of a granular solid reactant, where energy for the reaction is provided by a counter-current flow of hot gases through the porous reactant bed. Research into reacting flows typically focusses on exothermic combustion processes. However, endothermic processes are common in the metallurgy industry, including the production of cement, silicon and rutile titanium dioxide. Several common features are observed in experimental and numerical studies of these processes, including critical temperatures of the reactant at which the chemical reaction begins, and regions of the reactor with uniform reactant temperature. Motivated specifically by the processes in a silicon furnace, we analyse a model of endothermic, reacting counter-current flow using the method of matched asymptotic expansions. Assuming the Péclet number in the solid is large, we explore the full range of values for the dimensionless inter-phase heat-transfer rate, finding six distinguished limits. In all limits, we find a diffusive boundary layer in which there is a fast chemical reaction rate due to the high temperatures, analogous to exothermic flame fronts. Outside this region, the counter-current flow is crucial to the chemical processes. For intermediate values of the heat-transfer rate, we find the same qualitative properties as those observed across the metallurgy industry, and we quantify the dependence of these properties on the flow rate and heat-transfer rate. In the limit of large heat-transfer coefficient, we derive the single-temperature limit, in which the solution structure is dependent on the direction of net heat flux through the domain.
Bridging-droplet transfer from solid to porous surfaces
Authors: Murphy Kevin R. , Boreyko Jonathan B.
Published: September 2022

When the top of a sessile droplet is contacted by an opposing solid surface, the droplet can transfer depending on the wettabilities and relative velocity of the surfaces. What if the surface receiving the liquid was porous? High-speed imaging was used to capture the transfer of a droplet from a solid substrate to an opposing porous surface. The parameters that were varied include the wettability of the donor substrate, the pore size of the receiving surface and the droplet's volume and working fluid. Generally, the transfer process is split into two sequential regimes, wetting and wicking, with wicking being three orders of magnitude longer than wetting on average. The wetting regime is split into two sub-regimes, the donor-independent and donor-dependent regimes. The donor-independent regime follows the dynamics of droplet coalescence, starting in a mass-limited viscous regime followed by a capillary–inertial regime. The donor-dependent regime is driven by a global change in Laplace pressure across the liquid bridge, with the viscous wedge of the receding contact line being the rate-limiting factor. The wicking regime is governed by Darcy's law, completing the transfer process of the droplet.
Intermittent air invasion in pervaporating compliant microchannels
Authors: Keiser Ludovic , Marmottant Philippe , Dollet Benjamin
Published: September 2022

We explore air invasion in a dead-end compliant water-filled microchannel containing a constriction. The phenomenon is driven by the pervaporation of the liquid present in the channel through the surrounding medium. The penetration is intermittent, jerky and characterised by a stop-and-go dynamics as the bubble escapes the constriction. We demonstrate that this sequence of arrest and jump of the bubble is due to an elasto-capillary coupling between the air–liquid interface and the elastic medium. When the interface enters the constriction, its curvature increases strongly, leading to a depressurisation within the liquid-filled channel that drives a compression of the channel. As the interface is forced to leave the constriction at a given threshold pressure, due to the ongoing loss of liquid content by pervaporation, the pressure is suddenly released, which gives rise to a rapid propagation of the air bubble away from the constriction, and a restoration of the rest shape of the channel. Combining macroscopic observations and confocal imaging, we present a comprehensive experimental study of this phenomenon. In particular, the effect of the channel geometry on the time of arrest in the constriction and the jump length is investigated. Our novel microfluidic design succeeds in mimicking the role of inter-vessel pits in plants, which transiently stop the propagation of air embolisms during long and severe droughts. It is expected to serve as a building block for further biomimetic studies in more complex leaf-like architectures, in order to recover this universal phenomenon of intermittent propagation reported in real leaves.
The role of vibrations for reducing the resistance in the relative movement of parallel plates
Authors: Floryan J.M. , Haq N.N.
Published: September 2022

The effect of surface vibrations on the propulsion augmentation and resistance in the relative movement of parallel plates has been studied. The analysis was focused on monochromatic waves and laminar flows. The effectiveness of the vibrations was gauged by determining the external force required to maintain the movement of one of the plates at a prescribed velocity. It is shown that waves propagating upstream always increase the resistance but the flow response to waves propagating downstream is more intricate and is a function of the flow Reynolds number. In general, waves must be sufficiently fast to reduce the flow resistance. This leads to a natural division between slow and fast waves; a characterization that is helpful for flows at a sufficiently small Reynolds number Re. An increase in Re brings into play the complication of possible resonances with the natural flow frequencies. Resonances are not possible with waves faster than the plate velocity and these supercritical waves generally decrease the flow resistance. More complex flow responses can occur with slower (subcritical) waves which tend to increase the flow resistance. A complete elimination of the resistance is possible if the waves are of sufficiently short wavelength and travel quickly. This suggests that our mechanism has great potential in the development of propulsion augmentation systems. None of the waves produced net energy savings.
Motion of a sphere in a viscous density stratified fluid
Authors: Varanasi Arun Kumar , Subramanian Ganesh
Published: September 2022

We examine the translation of a sphere in a stratified ambient in the limit of small Reynolds numbers (

$Re \ll 1$

) and viscous Richardson numbers (

$Ri_v \ll 1$

); here,

$Re = {\rho Ua}/{\mu }$

and

$Ri_v = {\gamma a^3 g}/{\mu U}$

, with

$a$

being the sphere radius,

$U$

the translation speed,

$\rho$

and

$\mu$

the density and viscosity of the stratified ambient,

$g$

the acceleration due to gravity, and

$\gamma$

the density gradient characterizing the ambient stratification. In contrast to most earlier efforts, our study considers the convection-dominant limit corresponding to

$Pe = {Ua}/{D} \gg 1$

,

$D$

being the diffusivity of the stratifying agent. We characterize in detail the velocity and density fields around the particle in what we term the Stokes stratification regime, defined by

$Re \ll Ri_v^{{1}/{3}} \ll 1$

, and corresponding to the dominance of buoyancy over inertial forces. Buoyancy forces associated with the perturbed stratification fundamentally alter the viscously dominated fluid motion at large distances of order the stratification screening length that scales as

$a\,Ri_v^{-{1}/{3}}$

. The motion at these distances transforms from the familiar fore–aft symmetric Stokesian form to a fore–aft asymmetric pattern of recirculating cells with primarily horizontal motion within, except in the vicinity of the rear stagnation streamline. At larger distances, the motion is vanishingly small except within (a) an axisymmetric horizontal wake whose vertical extent grows as

$O(r_t^{{2}/{5}})$

,

$r_t$

being the distance in the plane perpendicular to translation, and (b) a buoyant reverse jet behind the particle that narrows as the inverse square root of distance downstream. As a result, for

$Pe = \infty$

, the motion close to the rear stagnation streamline starts off pointing in the direction of translation, in the inner region, and decaying as the inverse of the downstream distance; the motion reverses beyond distance

$1.15a\,Ri_v^{-{1}/{3}}$

, with the eventual reverse flow in the far-field buoyant jet again decaying as the inverse of the distance downstream. For large but finite

$Pe$

, the narrowing jet is smeared out beyond a distance of

$O(a\,Ri_v^{-{1}/{2}}\, Pe^{{1}/{2}})$

, leading to an exponential decay of the aforementioned reverse flow.
Artistic Censorship and Freedoms in French Public Law
Authors: Bioy Xavier
Published: September 2022

“I know that everyone is opposed to the idea of censorship of literary works. As for me, I believe that censorship can be justified, if it is exercised with probity and does not serve to cover up personal, racial or political persecution.” Thus pleaded Borges, with his taste, very paradoxical here, for provocation. The legitimization of a censorship which is “necessary” for society? This is perhaps also reflected by contemporary French law.
Mapping Antarctic and Arctic Women: An exploration of polar women’s experiences and contributions through place names
Authors: Devine Carol
Published: September 2022

In this commentary, I investigate the Poles differently, and in situ, rather than only as stereotypically barren uninhabited expansive places on a globe or maps. The human stories are behind the relatively white space on which few place names are marked. But the more visible ones are made and told through a male-dominated, colonial narrator and mapmaker, until more recently. Cartography, like history, has overwhelmingly documented men’s worlds, stories, dominations and accomplishments, creating a virtual whiteout of women’s and notably Indigenous women’s stories also in polar regions. In this commentary, I report on a journey into (re)mapmaking I did of women’s stories told through female place names and toponymies of women especially in the Antarctic, through a crowd-sourced project, Mapping Antarctic Women. I explore not only mapping female place names and women’s stories in the Arctic, exploring gendered, colonial and western culture mapping but also newer digital Indigenous place name mapping and also mapping of human-exacerbated changes in the ice that makes the Antarctic map.
There is no “inference within a model”
Authors: Facchin Marco
Published: September 2022

I argue that there is no viable development of the instrumentalist inference within a model research program. I further argue that both Friston and Pearl blankets are not the right sort of tool to settle debates on philosophical internalism and externalism. For these reasons, the inference within a model program is far less promising than the target article suggests.
Redressing the emperor in causal clothing
Authors: Btesh Victor J. , Bramley Neil R. , Lagnado David A.
Published: September 2022

Over-flexibility in the definition of Friston blankets obscures a key distinction between observational and interventional inference. The latter requires cognizers form not just a causal representation of the world but also of their own boundary and relationship with it, in order to diagnose the consequences of their actions. We suggest this locates the blanket in the eye of the beholder.
Return of the math: Markov blankets, dynamical systems theory, and the bounds of mind
Authors: Colling Lincoln John
Published: September 2022

Bruineberg and colleagues highlight work using Markov blankets to demarcate the bounds of the mind. This echoes earlier attempts to demarcate the bounds of the mind from a dynamical systems perspective. Advocates of mechanistic explanation have challenged the dynamical approach to independently motivate the application of the formalism, a challenge that Markov blanket theorists must also meet.
The seductive allure of cargo cult computationalism
Authors: Allen Micah
Published: September 2022

Bruineberg and colleagues report a striking confusion, in which the formal Bayesian notion of a “Markov blanket” has been frequently misunderstood and misapplied to phenomena of mind and life. I argue that misappropriation of formal concepts is pervasive in the “predictive processing” literature, and echo Richard Feynman in suggesting how we might resist the allure of cargo cult computationalism.
Free-energy pragmatics: Markov blankets don't prescribe objective ontology, and that's okay
Authors: Hipólito Inês , van Es Thomas
Published: September 2022

We target the ontological and epistemological ramifications of the proposed distinction between Friston and Pearl blankets. We emphasize the need for empirical testing next to computational modeling. A peculiar aspect of the free energy principle (FEP) is its purported support of radically opposed ontologies of the mind. In our view, the objective ontological aspiration itself should be rejected for a pragmatic instrumentalist view.
Markov blankets and Bayesian territories
Authors: Beck Jeff
Published: September 2022

Bruineberg et al. argue that one ought not confuse the map (model) for the territory (reality) and delineate a distinction between innocuous Pearl blankets and metaphysically laden Friston blankets. I argue that all we have are models, all knowledge is conditional, and that if there is a Pearl/Friston distinction, it is a matter of the domain of application: latents or observations. This suggests that, if anything, Friston blankets may inherit philosophical significance previously assigned to observations.
Relocation and Dislocation: Civilian, Refugee, and Military Movement as Factors in the Disintegration of Postwar China, 1945–49
Authors: Mitter Rana
Published: September 2022

This article argues that massive human displacement was one of the defining factors in China's immediate postwar period (1945–49). It shows that at least three distinctive groups were dispersed during the wartime years and needed to be resettled after the war ended in August 1945: civilian refugees, administrators who had been relocated to the temporary capital at Chongqing, and troops transferred in anticipation of an upcoming civil war between the Nationalists and the Communists. The article argues that China's new sovereign status in 1945 was paradoxically a source of weakness when it came to resettlement and reconstruction, as China sought international funds to undertake its own reconstruction, but could not demit responsibility to an external actor to organise matters as the United States did for western Europe. A growing sense of anomie and unsettlement prevented resettlement and China remained a zone in which international and domestic conflict came together. Both sets of factors shaped the dislocation that destroyed the possibilities of a stable resettlement in China after the great displacement of wartime.
Food insecurity is associated with self-reported oral health in school-age Ecuadorian children and is mediated by dietary and non-dietary factors
Authors: Weigel M Margaret , Armijos Rodrigo X
Published: September 2022

Objective:

The main objective was to investigate the association of household food insecurity (HFI) with child oral health. A secondary objective was to explore potential dietary and non-dietary mediators of the HFI–child oral health relationship.

Design:

Cross-sectional data from the nationally representative Ecuadorian National Health and Nutrition Survey (2018) were analysed. The data included self-reported child oral health, HFI (Food Insecurity Experience Scale), diet (FFQ) and oral care behaviours (toothbrushing frequency, toothpaste use). The association of HFI with the reported number of oral health problems was examined with stereotype logistic regression. Parallel mediation analysis was used to explore potential dietary (highly fermentable carbohydrate foods, plain water) and non-dietary (toothbrushing) mediators of the HFI–oral health relationship. Bias-corrected standard errors and 95 % CI were obtained using non-parametric bootstrapping (10 000 repetitions). Effect size was measured by percent mediation (PM).

Setting:

Ecuador.

Participants:

5–17-year-old children (n23 261).

Results:

HFI affected 23 % of child households. 38·5 % of children have at least one oral health problem. HFI was associated with a greater number of oral health problems: 1–2 problems (adjusted odds ratio (AOR) = 1·37; 95 % CI (1·15, 1·58);P= 0·0001), 3–4 problems (AOR = 2·21; 95 % CI (1·98, 2·44);P= 0·0001), 5–6 problems (AOR = 2·57; 95 % CI (2·27, 2·88);P= 0·0001). The HFI–oral health relationship was partially mediated by highly fermentable carbohydrate foods (PM= 4·3 %), plain water (PM= 1·8 %) and toothbrushing frequency (PM= 3·3 %).

Conclusions:

HFI was associated with poorer child oral health. The HFI–oral health relationship was partially mediated by dietary and non-dietary factors. Longitudinal studies are needed to replicate our findings and investigate the role of other potential mediators.
Effect of tumour involvement on activity determination of resin Yttrium-90 in selective internal radiation therapy of metastatic liver cancer
Authors: Li Jun , Yu Yan , Anne Rani
Published: September 2022

Introduction:

The study was aimed to evaluate the effect of tumour involvement on resin Yttrium-90 (Y90) activity determination for metastatic liver cancer treatment.

Methods:

One hundred and two cases of resin Y90 microsphere treatment were retrospectively studied. Body surface area (BSA) method was used in the calculation of resin Y90 activity. The total activity (TA) was calculated as a summation of activities obtained from BSA-based calculation and tumour involvement (TI). TI and TA of each case were evaluated. The contributions of TI to TA were calculated with the ratio of TI/TA.

Results:

The average contribution of TI to TA was 4·1%. The contributions were < 5·8% in 75% of the cases, < 2·2% in 50% of the cases and < 1·0% in 25% of the cases.

Conclusions:

Overall the effect of tumour involvement on the activity determination was small. The activity calculation could be simplified by neglecting TI in 25% of the cases where the activity contribution from TI was less than 1%. Contouring tumour and liver structures for TI calculation could be avoided in these cases, and the efficiency of the workflow for resin Y90 procedures could be improved.
Conceptualizing good global statehood: progressive foreign policy after the populist moment
Authors: Gilmore Jonathan
Published: September 2022

This article explores the theoretical challenges for normatively progressive foreign policy following the rise of populist nationalism during the 2010s, using analytical concepts from the English School. It argues that populist nationalism exposes a problem of internal dissensus on the future trajectories of solidarist international society, within the Western states that have traditionally been its principal supporters. The ‘populist moment’ reveals problems of disconnection between domestic publics, the practices, and institutions of contemporary international society, and state actions that are premised in part on ethical regard for non-citizens. The article contends that, as an interface point between rooted communities and global ethical concerns, progressive foreign policy approaches have an important role to play in ameliorating these disconnections. However, these approaches must look beyond a simple ‘re-booting’ of liberal internationalism, focussing instead on building a path towards solidarist international society that is rooted in everyday-lived experiences, communities, and identities within the state. Building upon theorizations of good international citizenship, the article advances an alternative framework of good global statehood, which draws upon a coproduction methodology as a means of creating progressive foreign policies that are better attuned to pluralism and diversity across, but also within state borders.
On the Improvement of Mass Load Inversion With GNSS Horizontal Deformation: A Synthetic Study in Central China
Authors: Wang Song‐Yun , Li Jin , Chen Jianli , Hu Xiao‐Gong
Published: September 2022

We carry out synthetic experiments of mass load inversion using Global Navigation Satellite System (GNSS) vertical and horizontal displacements in Central China. Using two synthetic mass load models from a checkerboard mass distribution and a more realistic distribution derived from the Gravity Recovery and Climate Experiment (GRACE) observations, the inverted mass changes are determined based on the load theory and then compared with the known mass‐change inputs. We find that the combination of horizontal displacements with the commonly used vertical displacements significantly improves the inversion results when the number of sites is larger than one third of the number of total grids with relatively uniform distribution over the region. Synthetic tests demonstrate that data from the Crustal Movement Observation Network of China, including the total number of GNSS sites, spatial distribution, and precision, are sufficient to infer the annual amplitudes of mass changes in the region with comparable spatial resolution as that of GRACE observations. For the current precision level of the GNSS surface displacements (3.0 mm in the vertical and 1.0 mm in the horizontal components), including horizontal displacements leads to ∼10% improvement in mass inversion, compared to using vertical displacements only. With a higher precision level of 0.50 and 0.17 mm (for vertical and horizontal components, respectively), an improvement of ∼20% can be achieved.
Comparing Model Representations of Physiological Limits on Transpiration at a Semi‐Arid Ponderosa Pine Site
Authors: Hawkins Linnia R. , Bassouni Maoya , Anderegg William R. L. , Venturas Martin D. , Good Stephen P. , Kwon Hyojung J. , Hanson Chad V. , Fiorella Richard P. , Bowen Gabriel J. , Still Christopher J.
Published: September 2022

Mechanistic representations of biogeochemical processes in ecosystem models are rapidly advancing, requiring advancements in model evaluation approaches. Here we quantify multiple aspects of model functional performance to evaluate improved process representations in ecosystem models. We compare semi‐empirical stomatal models with hydraulic constraints against more mechanistic representations of stomatal and hydraulic functioning at a semi‐arid pine site using a suite of metrics and analytical tools. We find that models generally perform similarly under unstressed conditions, but performance diverges under atmospheric and soil drought. The more empirical models better capture synergistic information flows between soil water potential and vapor pressure deficit to transpiration, while the more mechanistic models are overly deterministic. Although models can be parameterized to yield similar functional performance, alternate parameterizations could not overcome structural model constraints that underestimate the unique information contained in soil water potential about transpiration. Additionally, both multilayer canopy and big‐leaf models were unable to capture the magnitude of canopy temperature divergence from air temperature, and we demonstrate that errors in leaf temperature can propagate to considerable error in simulated transpiration. This study demonstrates the value of merging underutilized observational data streams with emerging analytical tools to characterize ecosystem function and discriminate among model process representations.
Study of the Average Ion Mass of the Dayside Magnetospheric Plasma
Authors: Del Corpo Alfredo , Vellante Massimo , Zhelavskaya Irina S. , Shprits Yuri Y. , Heilig Balázs , Reda Jan , Pietropaolo Ermanno , Lichtenberger János
Published: September 2022

The investigation of heavy ions dynamics and properties in the Earth's magnetosphere is still an important field of research as they play an important role in several space weather aspects. We present a statistical survey of the average ion mass in the dayside magnetosphere made comparing plasma mass density with electron number density measurements and focusing on both spatial and geomagnetic activity dependence. Field line resonance frequency observations across the European quasi‐Meridional Magnetometer Array, are used to infer the equatorial plasma mass density in the range of magnetic L‐shells 1.6–6.2. The electron number density is derived from local electric field measurements made on Van Allen Probes using the Neural‐network‐based Upper‐hybrid Resonance Determination algorithm. The analysis is conducted separately for the plasmasphere and the plasmatrough during favorable periods for which both the plasma parameters are observed simultaneously. We found that throughout the plasmasphere the average ion mass is ≃1 amu for a wide range of geomagnetic activity conditions, suggesting that the plasma mainly consist of hydrogen ions, without regard to the level of geomagnetic activity. Conversely, the plasmatrough is characterized by a variable composition, highlighting a heavy ion mass loading that increases with increasing levels of geomagnetic disturbance. During the most disturbed conditions, the average radial structure shows a broad maximum around 3–4 Earth radii, probably correlated with the accumulation of oxygen ions near the plasmapause. Those ions are mostly observed in the post‐dawn and pre‐dusk longitudinal sectors.
A New Madrid Seismic Zone Fault System Model From Relative Event Locations and Application of Optimal Anisotropic Dynamic Clustering
Authors: Zhang Yixin , Fadugba Oluwaseun , Powell Christine , Horton Stephen , Langston Charles A.
Published: September 2022

A refined model of fault structure in the active New Madrid Seismic Zone (NMSZ) is presented based on relocated hypocenters and application of a statistical clustering method to determine fault planes. Over 200 earthquakes are recorded in the NMSZ every year, but the three‐dimensional (3‐D) fault structure is difficult to determine because the zone is covered by thick, Mississippi Embayment sediment. The distribution of earthquakes in the NMSZ indicates four major arms of seismicity, suggesting the presence of a northeast‐southwest trending strike‐slip fault system with a major northwest trending, contractional stepover fault. Relocation of 4,131 earthquakes using HypoDD resulted in major improvement in the depiction of fault structure in the NMSZ including three‐dimensional structural variations along the along the Reelfoot fault (RF) and a well‐defined intersection of the Axial and RFs. Optimal Anisotropic Dynamic Clustering analysis of the relocated hypocenters produced a fault model consisting of 12, well resolved planes. The RF is continuous along strike from the northern end to the Ridgely fault, located south of the intersection with the Axial fault (AF). The crosscutting Ridgely fault may serve as a barrier to rupture propagation along the entire fault. The strike‐slip arms of seismicity are well resolved and correspond to near vertical planes. Three planes are resolved in the southern part of the AF and are associated with the Osceola igneous complex.
A Directional Decomposition Method to Estimate the Reflection and Transmission of Nonlinear Internal Waves Over a Slope
Authors: Gong Yankun , Xie Jieshuo , Xu Jiexin , Chen Zhiwu , He Yinghui , Cai Shuqun
Published: September 2022

Multi‐directional propagating nonlinear internal waves (NLIWs) create complex spatial patterns, often making it difficult to quantitatively estimate the reflection and dissipation processes of NLIW energy over a slope. To identify the onshore‐ and offshore‐going wave signals in a regional model, we apply a directional Fourier filter (DFF) method to clarify wave dynamics over varying slopes. First, a series of two‐dimensional analytical solutions of either solitons or NLIW packets are utilized. Next, two‐dimensional numerical experiments indicate that the rate of reflection (dissipation) of energy for the shoaling NLIWs is much lower (higher) than that for the shoaling internal tides over a slope, regardless of varying slope criticality and height. Finally, we apply the DFF method in a three‐dimensional non‐hydrostatic regional model (MITgcm) to directionally decompose the onshore‐ and offshore‐going internal waves (IWs) on the Australian North West Shelf. The model results show that mode‐1 incoming internal tides gradually steepen into NLIWs during the shoaling processes over the slope, and then the reflecting IWs are propagate offshore in the main form of linear IW beams. In addition, the reflectivity of IWs around the Imperieuse Reef is 60% and the offshore‐reflecting IWs quickly dissipate accompanied by an e‐folding length scale of ∼22 km.
The Changing Amazon Hydrological Cycle—Inferences From Over 200 Years of Tree‐Ring Oxygen Isotope Data
Authors: Baker Jessica C. A. , Cintra Bruno B. L. , Gloor Manuel , Boom Arnoud , Neill David , Clerici Santiago , Leng Melanie J. , Helle Gerhard , Brienen Roel J. W.
Published: September 2022

Changes to the Amazon hydrological cycle have important consequences for world's largest tropical forest, and the biodiversity it contains. However, a scarcity of long‐term climate data in the region makes it hard to contextualize recent observed changes in Amazon hydrology. Here, we explore to what extent tree‐ring oxygen isotope (δ18OTR) chronologies can inform us about hydrological changes in the Amazon over the past two centuries. Two δ18OTR records from northern Bolivia and the Ecuadorian Andes are presented. The Ecuador record spans 1799–2012 (n = 16 trees) and the Bolivia record spans 1860–2014 (n = 32 trees), making them the longest δ18OTR records from the Amazon, and among the most highly‐replicated δ18OTR records from the tropics to date. The two chronologies correlate well at interannual and decadal timescales, despite coming from sites more than 1,500 km apart. Both δ18OTR records are strongly related to interannual variation in Amazon River discharge measured at Óbidos, and accumulated upwind precipitation, suggesting a common climatic driver. In both records a strong increase in δ18OTR was observed up until approximately 1950, consistent with positive trends in the few other existing δ18O proxy records from across the Amazon. Considering all possible drivers of this long‐term increase, a reduction in rainout fraction over the basin driven by rising sea surface temperatures in the North Atlantic is suggested as the most likely cause. The upward trend in δ18OTR reverses over the past 1–2 decades, consistent with the observed strengthening of the Amazon hydrological cycle since approximately 1990.
Class-specific diffractive cameras based on deep learning-designed surfaces
Authors: Zhou Xuxi , Wang Shuming
Published: September 2022

Recently, a new diffractive camera design based on transmissive surfaces structured using deep learning is proposed. It performs class-specific imaging of target objects and all-optical deletion of other classes of objects, which will promote the development of privacy-preserving digital cameras and mission-specific data.
Optical clearing of the mouse skull
Authors: Xu Chris
Published: September 2022

High spatial resolution imaging of the mouse brain through the intact skull is challenging because of the skull-induced aberration and scattering. The research group of Dan Zhu from Huazhong University of Science and Technology has developed a skull-clearing technique that provides a long-term (~ weeks), stable, transparent window for high resolution optical imaging over a large field of view.
An ultrasensitive and stretchable strain sensor based on a microcrack structure for motion monitoring
Authors: Sun Hao , Fang Xudong , Fang Ziyan , Zhao Libo , Tian Bian , Verma Prateek , Maeda Ryutaro , Jiang Zhuangde
Published: September 2022

Flexible strain sensors are promising candidates for intelligent wearable devices. Among previous studies, although crack-based sensors have attracted a lot of attention due to their ultrahigh sensitivity, large strain usually causes fractures in the conductive paths. Because of the unstable crack structure, the tradeoff between sensitivity and workable strain range is still a challenge. As carbon nanotubes (CNTs) and silver nanowires (AgNWs) can form a strong interface with the thermoplastic substrate and strengthen the conductive network by capillary force during water evaporation, CNTs and AgNWs were deposited on electrospun TPU fiber mats via vacuum-assisted filtration in this work. The prestretching treatment constructed a microcrack structure that endowed the sensor with the combined characteristics of a wide working range (0~171% strain), ultrahigh sensitivity (a gauge factor of 691 within 0~102% strain, ~2 × 104 within 102~135% strain, and >11 × 104 within 135~171% strain), a fast response time (~65 ms), small hysteresis, and superior durability (>2000 cycles). Subsequently, the sensing mechanism of the sensor was studied. Distributed microcrack propagation based on the “island-bridge” structure was explained in detail, and its influence on the strain-sensing behavior of the sensor was analyzed. Finally, the sensor was assembled to monitor various vibration signals and human motions, demonstrating its potential applications in the fields of electronic skin and human health monitoring.
Short-acting β2-agonist prescription patterns for asthma management in the SABINA III primary care cohort
Authors: Price David , Hancock Kerry , Doan Joseph , Taher Sri Wahyu , Muhwa Chakaya J. , Farouk Hisham , Beekman Maarten J. H. I.
Published: September 2022

Short-acting β2-agonist (SABA) prescriptions and associated outcomes were assessed in 1440 patients with asthma from the SABA use IN Asthma (SABINA) III study treated in primary care. Data on asthma medications were collected, and multivariable regression models analysed the association of SABA prescriptions with clinical outcomes. Patients (mean age, 47.9 years) were mostly female (68.6%); 58.3% had uncontrolled/partly controlled asthma and 38.8% experienced ≥1 severe exacerbation (reported in 39% of patients with mild asthma). Overall, 44.9% of patients were prescribed ≥3 SABA canisters (over-prescription) and 21.5% purchased SABA over-the-counter. Higher SABA prescriptions (vs 1−2 canisters) were associated with significantly decreased odds of having at least partly controlled asthma (6–9 and 10–12 canisters) and an increased incidence rate of severe exacerbations (10–12 and ≥13 canisters). Findings revealed a high disease burden, even in patients with ‘mild’ asthma, emphasising the need for local primary care guidelines based on international recommendations.