bluuebunny/crossref_metadata_2025 huggingface dataset:
Impairment Model of Financial Instruments
Authors: Prada Segura Jasleidy Astrid
Published: April 2023

Through an applied exercise, this research article sought to document the impairment model of financial instruments proposed by the International Financial Reporting Standard (IFRS 9). For this purpose, an investigation was used based on the documentary data source, with a qualitative approach and descriptive-explanatory scope. Among the main findings, it is found that the application of the new impairment requirements of IFRS 9 presupposes an increase in the provisions for credit losses of the organizations, in which the need to use methodologies to estimate the probability is evident of non-compliance as a safeguard measure for organizations.
Academic factors associated with the formative research process in the educational institutions of the official sector of Sincelejo, Sucre
Authors: Álvarez Contreras Diana Esther , Díaz Pérez Consuelo María , Herazo Morales Reinaldo
Published: April 2023

The study's objective was to describe the academic factors associated with developing the formative research process in public educational institutions in the municipality of Sincelejo. For this purpose, a quantitative and descriptive methodology was used, applying surveys to the students and teachers of the sample of 14 educational institutions; Additionally, a documentary analysis was carried out based on the variable of academic factors. Among the most relevant results, it was determined that the academic factor, which prevails in formative research from the student's perspective, is linked to the pedagogical practice implemented by teachers. It is concluded that the traditional model based on the transmission of knowledge and its accumulation predominates in educational institutions. At the same time, some oriented towards formative research and learning by doing have been implemented.
Peran Inovasi dalam Meningkatkan Kinerja Industri Pariwisata Berkelanjutan di Indonesia
Authors: Achmad Fandi
Published: April 2023

Inovasi memiliki peran yang sangat penting dalam meningkatkan kualitas produk dan layanan yang ditawarkan oleh industri pariwisata yang sangat kompetitif. Penelitian ini bertujuan untuk menjelaskan peran inovasi dalam industri pariwisata untuk mencapai kinerja yang optimal. Metode penelitian yang digunakan dalam penelitian ini adalah penelitian deskriptif yang dilakukan dengan cara melakukan studi literatur mengenai peran inovasi dalam industri pariwisata. Data yang diperoleh dianalisis dengan menggunakan teknik analisis deskriptif. Hasil penelitian menunjukkan bahwa inovasi memiliki peran yang sangat penting dalam meningkatkan kualitas produk dan layanan di industri pariwisata. Inovasi membantu industri pariwisata untuk mencapai kinerja yang optimal dengan menciptakan produk dan layanan yang menarik bagi pelanggan, meningkatkan efisiensi operasional, dan meningkatkan pangsa pasar. Dengan adanya inovasi, industri pariwisata dapat mencapai industri yang berkelanjutan karena akan berdampak terhadap ekonomi, sosial dan lingkungan. Namun, penelitian ini juga menunjukkan bahwa masih banyak perusahaan di industri pariwisata yang belum memahami sepenuhnya pentingnya inovasi dan kurang mendorong pengembangan inovasi.
Prosedur Proses Sertifikasi P-IRT (Pangan-Industri Rumah Tangga) pada UMKM Pasca-Pandemi Covid 19
Authors: Kurniaji Kalfajrin
Published: April 2023

Ketahanan pangan nasional merupakan hal yang sangat penting dan menjadi perhatian seluruh stakeholder terutama dalam kondisi ancaman resesi pasca Pandemi Covid 19. Stakeholder penting dalam perwujudan ketahanan pangan adalah pelaku UMKM sebagai penyedia produk pangan yang tersebar di seluruh Indonesia. Peredaran produk pangan diatur pemerintah dengan menetapkan persyaratan pemenuhan izin P-IRT. Izin P-IRT merupakan sertifikasi yang ditetapkan pemerintah melalui UU No. 18 tahun 2012 dengan dipertegas oleh Per-BPOM No. 10 tahun 2021, yang mengatur keamanan produk pangan dari bahan baku, proses pengolahan, hingga produk akhir, Oleh karena itu proses pembuatan P-IRT dinilai penting dengan penjelasan prosedur lengkapnya. Pendekatan penelitian menggunakan deskriptif kualitatif. dengan metode observasi, wawancara dan studi pustaka. Hasil penelitian menunjukkan bahwa prosedur pembuatan izin P-IRT mengalami perubahan yang diakibatkan oleh kondisi pandemi Covid 19 serta adanya UU tentang Cipta kerja No. 11 tahun 2020. Fenomena perubahan SOP (Standar Operasional Prosedur) tersebut melibatkan proses yang berbasis teknologi informasi sehingga menghasilkan outcomes berupa pelayanan yang lebih cepat dan terhindar dari praktek percaloan.
Gambaran Cyber-Aggression Remaja Pengguna Fake Account Di Media Sosial
Authors: Farisandy Ellyana Dwi , Gunawan Sherliana , Anastasia Melany Kaihatu Veronica
Published: April 2023

Remaja merupakan pengguna paling aktif di media sosial. Selain itu, sebagian besar remaja memiliki setidaknya satu akun palsu (fake account) di media sosial. Adanya akun palsu dapat membuat remaja bisa melakukan apapun tanpa khawatir akan konskuensinya, salah satunya adalah dengan melakukan cyber-agression. Selain itu, remaja masih sulit untuk mengendalikan emosi dikarenakan otak bagian frontal cortex belum berkembang secara sempurna. Penelitian ini bertujuan melihat gambaran cyber-agression remaja pengguna fake account di media sosial. Responden penelitian ini merupakan remaja berusia 13-18 tahun, pengguna fake account di media sosial, dan menghabiskan waktu di media sosial minimal satu jam per hari. Alat ukur yang digunakan adalah Cyber-Aggression Typology Questionnaire (CATQ) yang menghasilkan empat tipe cyber-aggression. Hasil penelitian menunjukkan bahwa mayoritas remaja memiliki tipe impulsive-aversive aggression. Hal ini berarti bahwa remaja melakukan cyber-aggression secara spontan dengan tujuan ingin mengurangi perasaan negatif yang dirasakan.
Pengaruh Dukungan Sosial, Strategi Coping, Resiliensi, dan Harga Diri Terhadap Kesejahteraan Psikologis Siswa SMA di Kota Sukabumi
Authors: Mahendika Devin , Sijabat Saut Gracer
Published: April 2023

Penelitian ini bertujuan untuk menguji pengaruh dukungan sosial, strategi coping, resiliensi, dan harga diri terhadap kesejahteraan psikologis siswa SMA di Kota Sukabumi. Sebanyak 400 siswa SMA berpartisipasi dalam penelitian ini, dan data dikumpulkan menggunakan kuesioner laporan diri. Hasil penelitian menunjukkan bahwa keempat faktor berkorelasi positif dengan kesejahteraan psikologis, dengan dukungan sosial, strategi coping, dan ketahanan memiliki dampak yang lebih kuat daripada harga diri. Interaksi antara dukungan sosial dan resiliensi ditemukan memiliki pengaruh yang signifikan terhadap kesejahteraan psikologis. Temuan ini menunjukkan bahwa mempromosikan dukungan sosial dan keterampilan membangun ketahanan mungkin merupakan strategi yang efektif untuk meningkatkan kesejahteraan psikologis siswa sekolah menengah. Pendekatan komprehensif yang memperhitungkan banyak faktor diperlukan untuk mengatasi kesejahteraan psikologis siswa sekolah menengah.
Influence of Innovation, Creativity, and Risk-Taking on Entrepreneurial Growth and SMEs Performance in Sukabumi City
Authors: Dahlan  , Priyana Yana , Syam Rahmawati
Published: April 2023

This study explores the influence of innovation, creativity, and risk-taking on entrepreneurial growth and SMEs performance in Sukabumi City, Indonesia. A survey was conducted with 150 SMEs in the region to collect data on their innovation, creativity, risk-taking behavior, and performance indicators. The results suggest that innovation and creativity significantly impact SME growth and performance, while risk-taking has a weaker impact. These findings have important implications for policymakers and SMEs owners or managers in Sukabumi City and other regions with similar economic contexts, highlighting the need to promote and support innovative and creative practices among SMEs.
Climate Change, Agricultural Production, Food Security, and Livelihoods of Rural Communities in Rural Districts: A Qualitative Approach
Authors: Rusmayandi Gusti , Indriyani  , Hertini Etty Sri , Harahap Muhammad Ade Kurnia , Nugroho Rahmat Joko
Published: April 2023

Climate change significantly impacts agricultural production, food security, and livelihoods of rural communities in Sukabumi District. This study examines the relationship between climate change, agricultural production, food security, and the livelihoods of rural communities in the Sukabumi District. The study used a qualitative approach, including household surveys, interviews with key informants, and focus group discussions, to gather in 20 villages. Studies have found that climate change has led to a decline in crop yields, which has led to food insecurity and decreased incomes and livelihood opportunities for rural communities. Studies have also found that rural communities have used various adaptation strategies to cope with the impacts of climate change. However, these strategies are not enough to fully address the challenges faced by rural communities. The study's findings highlight the need for effective adaptation strategies to help rural communities cope with the impacts of climate change. In addition, the study findings point to the need for more investment in climate change research and monitoring, especially at the local level, to better understand the impact of climate change on rural communities and to provide foundational information for evidence-based policymaking and decision-making. Studies have limitations, including limited sample size and reliance on self-reported data. Future research could use a longitudinal design and incorporate more objective measures of agricultural productivity and food security to understand better climate change's impact on rural communities in Sukabumi District.
Effects of Age, Sex, Personality Traits, and Social Support on Successful Aging: A Longitudinal Study of Older Adults in Sukabumi City
Authors: Tiwery Weldemina Yudit , Heriani Istiana , Rusvitawati Devi
Published: April 2023

This longitudinal study investigated the effect of age, sex, nursing care characteristics, and social support on successful aging outcomes among elderly adults in KotaSukabumi, Indonesia. 260 participants completed baseline assessments and a 12-month follow-up on physical health, psychological well-being, and social engagement. Results showed that social support was positively associated with all three successful aging outcomes at follow-up, while nursing care characteristics were positively related to social engagement at follow-up. Age was negatively associated with physical health and social engagement at follow-up, and gender was not significantly related to successful aging outcomes. These findings emphasize the importance of social support and nursing care in promoting successful aging and suggest that interventions to improve these factors could effectively improve the health and well-being of elderly adults.
Comparison of area under the curves for vancomycin from one- and two-compartment models using sparse data
Authors:   , Maung Nyein
Published: April 2023

Vancomycin pharmacokinetics has been described by 1- and 2-compartment models. One-compartment models built from routine monitoring data, which were mainly trough samples, are commonly used to predict area under the curves (AUC), the useful indicator for vancomycin efficacy. The question stands whether AUCs from 1-compartment models with sparse data can sufficiently represent the true AUC. This study aimed to compare AUCs from 1- and 2-compartment models using sparse data. A previously published model was used to simulate full individual profiles for 100 patients. From these data, the reference AUC (AUCref) was calculated and two depleted datasets (trough-only and peak-trough) were also created. Both 1- and 2-compartment models were built from the depleted datasets using NONMEM®. AUC was calculated from concentration-time profiles of each model by linear trapezoidal method. Deviation of each AUC from the AUCref was examined from statistical and clinical perspectives. A two-compartment model from peak-trough data provided similar AUCs with the AUCref, but not that from trough-only data. The mean difference of AUCref and AUCs from the 2-compartment model with trough only data was up to 25.16% (p < 0.05) which were considered clinically significant. One-compartment models from both datasets could adequately estimate the AUCs with no significant differences (p > 0.05) from the AUCref. The mean differences were up to 4.38% and 6.23% for peak-trough and trough only data, respectively. Therefore, 1-compartment models from sparse data may be trustable to predict vancomycin AUC in clinical practice.
Population pharmacokinetics of intravenous colistin in pediatrics (poppicop study)
Authors:   , Wacharachaisurapol Noppadol
Published: April 2023

Background: Colistin use in pediatrics is surging in line with the increase of multidrug-resistant Gram-negative bacteria (MDR-GNB). However, the appropriate dose is uncertain owing to the lack of pharmacokinetics data. In this study, we aimed to characterize the pharmacokinetic parameters of colistin in pediatric patients, identify the factors influencing the pharmacokinetic parameters, and propose optimal dosage regimens.
Methods: A prospective, multicenter, population pharmacokinetic (PPK) study was conducted. Serial blood samples were obtained from patients after receiving the standard colistin recommended dose of 5 mg of colistin base activity (CBA)/kg/day. Plasma colistin concentrations were measured. Data were pooled from this study and the previous study to create a data set for PPK analysis. A PPK model was performed with the PhoenixTM 64 version 8.3. The final model was evaluated by goodness-of-fit plots, bootstrap analysis, and prediction corrected-visual predictive check. Simulation using the final PPK model was done to propose optimal colistin dosage regimens.
Results: From March 2018 to February 2021, 59 patients (187 plasma samples) were enrolled. Data were pooled with 20 patients (147 plasma samples) from the previous study. A total of 334 plasma colistin concentrations from 79 pediatric patients with a median age (IQR) of 2.6 years (0.8-6.8) were adequately described by a one-compartment model with first-order elimination along with serum creatinine (SCr) as a significant covariate on colistin clearance (CL). Colistin CL was 0.069 L/h*kg, the volume of distribution (V) was 0.658 L/kg. Model-based simulation demonstrated that with the recommended dose of 5 mg of CBA/kg/day, the probability target attainment (PTA) was 18.2-30.1% and 40.2-63.0% in the patients with a SCr level of 0.1-0.3 mg/dL and 0.31-0.75 mg/dL, respectively when the target plasma colistin average steady-state concentration (Css,avg) was 2 mg/L. For a lower target Css,avg of 1 mg/L, PTA was 61.1–75.0% and 82.6–93.6% in the patients with a SCr level of 0.1-0.3 mg/dL and 0.31-0.75 mg/dL, respectively.
Conclusions: SCr is a significant covariate on colistin clearance in pediatric patients. Patients with a lower SCr level require a higher dose of colistin, especially higher than the current recommendation, owing to the increase of colistin elimination.
Multi-evidence learning for medical diagnosis
Authors:   , Yampaka Tongjai
Published: April 2023

In recent years, a great many approaches for learning from multiple sources by considering the diversity of different views have been proposed. The most interesting field is medical diagnosis. For example, breast cancer screening normally employs two views of mammography (Cranio-Caudal and Medio-Lateral-Oblique) or two modes of ultrasound (B-mode and Doppler mode) breast images. This study proposes a multi-evidence learning model that combines the multiple evidences of breast images to improve diagnosis. Two views mammography and two modes of ultrasound were used. Our proposed model consists of four stages. First, feature extraction using Convolutional Neuron Networks was operated to extract the image features on each view separately. Second, feature selection by exploring the mutual information between the feature and the class label was used to select the informative features. Third, canonical correlation analysis was explored to merge two feature sets into one final layer. Finally, the classification of malignant or benign was performed using a support vector machine. The experiment results indicated that the proposed method increases the classification performance. In addition, not only high accuracy but also the maximal correlation has been achieved with combined views.
รูปแบบการเรียนรู้แบบเชื่อมโยงเพื่อเสริมสร้างความเป็นพลเมืองวิวัฒน์ในการพัฒนาท้องถิ่นสําหรับนักศึกษามหาวิทยาลัยราชภัฏ
Authors:   , รังษีสุทธาภรณ์ เกวลี
Published: April 2023

การจัดการศึกษาระดับอุดมศึกษาท่ามกลางโลกดิจิทัล  โดยเฉพาะนักศึกษาของมหาวิทยาลัยราชภัฏที่มีพื้นที่ครอบคลุมทั่วทั้งประเทศ ในการปลูกฝังและเสริมสร้างให้เป็นพลเมืองที่มีความรับผิดชอบต่อสังคม รู้เท่าทันโลกของดิจิทัลหรือ พลเมืองวิวัฒน์ การวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาสภาพปัจจุบัน และปัญหาการพัฒนาพลเมืองวิวัฒน์ของนักศึกษาในสถาบันอุดมศึกษา ประเมินคุณลักษณะความเป็นพลเมืองวิวัฒน์ของนักศึกษามหาวิทยาลัยราชภัฏ และพัฒนารูปแบบการเรียนรู้แบบเชื่อมโยงเพื่อเสริมสร้างความเป็นพลเมืองวิวัฒน์ในการพัฒนาท้องถิ่นสำหรับนักศึกษามหาวิทยาลัยราชภัฏ กลุ่มตัวอย่างที่ใช้ในการวิจัยมี 6 กลุ่มคือ 1) ผู้ทรงคุณวุฒิจำนวน 10 คน 2)อาจารย์สำหรับการสัมภาษณ์เกี่ยวกับกระบวนการจัดการเรียนรู้เพื่อพัฒนาพลเมืองวิวัฒน์จำนวน 9 คน 3) อาจารย์มหาวิทยาลัยราชภัฏ จำนวน 380 คน 4) นักศึกษามหาวิทยาลัยราชภัฏจำนวน 760 คน 5) นักศึกษากลุ่มทดลอง 40 คน และ 6) ผู้เชี่ยวชาญจำนวน 12 คน เครื่องมือที่ใช้ในการวิจัยประกอบด้วย แบบสัมภาษณ์ แบบสอบถาม แบบประเมิน และแบบบันทึก การวิเคราะห์ข้อมูลใช้การวิเคราะห์เนื้อหา และสถิติเชิงบรรยาย ผลการวิจัยพบว่า

1. คุณลักษณะพลเมืองวิวัฒน์เพื่อการพัฒนาท้องถิ่น ประกอบด้วย 3 มิติคือ มิติความรู้ ประกอบด้วยมิติย่อย การรู้สารสนเทศ การรู้เทคโนโลยีสารสนเทศและการสื่อสาร และการรู้สังคม มิติทักษะ ประกอบด้วยมิติย่อย การเข้าถึงสารสนเทศด้วยเทคโนโลยีดิจิทัล การประเมินสารสนเทศ และการสร้างสรรค์บูรณาการ และมิติทัศนคติ ประกอบด้วยมิติย่อย จิตสำนึกด้านสังคม การเคารพสังคม และความรับผิดชอบต่อสังคม

2. กระบวนการเรียนการสอนที่ส่งเสริมความรับผิดชอบต่อสังคม และการมีส่วนร่วมในชุมชนให้กับนักศึกษาคือ การเรียนรู้ผ่านกิจกรรม และนักศึกษามหาวิทยาลัยราชภัฏควรมีคุณลักษณะการรู้สังคม มากที่สุด

3. คุณลักษณะความเป็นพลเมืองวิวัฒน์ของนักศึกษามหาวิทยาลัยราชภัฏอยู่ในระดับมาก ทุกมิติ

4. รูปแบบการเรียนรู้แบบเชื่อมโยงเพื่อเสริมสร้างความเป็นพลเมืองวิวัฒน์ในการพัฒนาท้องถิ่นสำหรับนักศึกษามหาวิทยาลัยราชภัฏประกอบด้วย สาระการเรียนรู้เรื่องการรู้ดิจิทัล 6 เรื่อง ผ่านกระบวนการเรียนรู้แบบเชื่อมโยง 7 กลยุทธ์ควบคู่ไปกับวิธีการเรียนรู้ 7 วิธี ใช้เวลาการเรียน 12 สัปดาห์ 36 ชั่วโมง วัดผลการเรียนรู้จากการสะท้อนคิด การบันทึกกิจกรรมการเรียนรู้ และการสังเกต

5. ประสิทธิผลของรูปแบบการเรียนรู้แบบเชื่อมโยงเพื่อเสริมสร้างความเป็นพลเมืองวิวัฒน์ในการพัฒนาท้องถิ่นสำหรับนักศึกษามหาวิทยาลัยราชภัฏ พบว่าค่าเฉลี่ยคุณลักษณะความเป็นพลเมืองวิวัฒน์ของนักศึกษามหาวิทยาลัยราชภัฏหลังทดลองเพิ่มขึ้นอยู่ในระดับมากที่สุดทุกมิติ (ค่าเฉลี่ย 4.65) และสูงกว่าก่อนทดลอง (ค่าเฉลี่ย 4.20) อย่างมีนัยสำคัญทางสถิติที่ระดับ .05 (p=.000)

จากการนำรูปแบบการเรียนรู้แบบเชื่อมโยงไปประยุกต์ใช้นั้นสามารถเพิ่มสมรรถนะด้านทักษะได้มากที่สุด สรุปได้ว่ารูปแบบการเรียนรู้แบบเชื่อมโยงเพื่อเสริมสร้างความเป็นพลเมืองวิวัฒน์ในการพัฒนาท้องถิ่นสำหรับนักศึกษามหาวิทยาลัยราชภัฏ เป็นการเรียนรู้เชิงรุกโดยเรียนรู้จากประสบการณ์ สิ่งสำคัญคือเรียนรู้ร่วมกันระหว่างผู้เรียน ผู้สอน และชุมชน
Anti-proliferative metabolites from the root of calophyllum inophyllum L.
Authors:   , Haerani Syahadatain
Published: April 2023

This study aimed to isolate secondary metabolites from the root of C. inophyllum L. and to evaluate their anti-proliferative activities against hepatocellular carcinoma and colorectal cancer cells. Chromatographic fractionation of the n-hexane and ethyl acetate crude extracts led to the isolation of two new (1 and 2) and twelve known xanthones (3-14). In addition, metabolites 4, 6 and 8 were isolated from the genus Calophyllum for the first time. All metabolites were evaluated for their anti-proliferative activity against Hep-G2 and HCT-116 cell lines. Metabolites 5 and 14 showed the most active metabolites against both cancer cells, as well as they displayed strong activities toward HCT-116 with the same IC50 value of 3.04 µM. Moreover, both of them exhibited potent activities against Hep-G2 with IC50 values of 6.07 and 5.94 µM, respectively. Further, metabolite 14 was subjected to western blot analysis to study its mechanism of action against Hep-G2 cells. The result demonstrated that 14 induced apoptosis in a concentration-dependent manner by the down-regulation of the expression of both Bcl-2 and Bcl-XL proteins.
Simple headspace device for determination of volatile compounds in food and drug samples
Authors:   , Meesuwan Kamonwan
Published: April 2023

This work presented a simple alternative method for simultaneous extraction and determination of volatile compounds in complex matrix samples by combining headspace technique with paper based colorimetric method. The paper loaded with colorimetric reagent that was attached to the liner of the vial cap making a simple headspace device for direct detection of the semi-volatile and volatile compounds in headspace extraction mode. A sample was placed in a vial sealed with the paper-based headspace device. The method was tested for determination of volatile compound using ethanol as a model and semi-volatile compound using iodine as a model in complex matrix samples. Ethanol volatilized and reacted with chromic acid reagent, which was generated by mixing sodium or potassium dichromate with sulfuric acid, on the paper. The orange color of solution containing dichromate (VI) change to green solution containing chromium (III) ions. Iodine was volatilized by using oxidizing agent and react with starch reagent on the paper. The colorless of starch solution change to dark blue color of iodine-starch solution. The image of the paper was taken by the scanner for determination of iodine and by digital camera for determination of alcohol. The images were processing by ImageJ software in RGB mode and the blue intensity was taken for quantification. For determination of alcohol, the sample was heated at 40 o C for 5 min. The method was applied for determination of alcohol content in drug (i.e., stomachic mixtures and Salol et menthol mixture), and beverage sample (i.e., beer). The linear calibration ranged from 0-7 % (v/v) of ethanol with R2 > 0.97 was obtained. The recovery of 94-120% and the relative standard deviation of less than 3% were achieved. For determination of iodine, the treatment of spiked egg sample with 0.4 g/mL TCA was heated at 50 o C for 15 min. The linear calibration ranged from 0-100 ppm of iodine with R2 > 0.98 was obtained. The recovery of 93% and the  relative standard deviation of less than 2% were achieved.
NGHIÊN CỨU SỰ HÀI LÒNG CỦA GIẢNG VIÊN TẠI MỘT TRƯỜNG ĐẠI HỌC Ở HÀ NỘI
Authors: Nguyễn Thị Vân Anh
Published: April 2023

Mục tiêu chính của nghiên cứu nhằm đánh giá sự hài lòng của giảng viên tại một trường Đại học ở Hà Nội và tìm ra một số phương pháp phù hợp để cải thiện mức độ hài lòng của giảng viên. Để đạt được mục tiêu này, dữ liệu thu thập thông qua bảng khảo sát điều tra dành cho giảng viên cơ hữu đang công tác tại trường. Dữ liệu được thu thập và phân tích theo phương pháp phân tích thống kê mô tả, phân tích phương sai một yếu tố ANOVA. Kết quả nghiên cứu cho thấy giảng viên khá hài lòng với cơ sở giáo dục về công việc, khả năng thăng tiến cũng như mối quan hệ với đồng nghiệp. Tuy nhiên, cơ sở giáo dục vẫn có thể nghiên cứu và áp dụng những khuyến nghị được nêu ra trong nghiên cứu này để nâng cao chất lượng của môi trường làm việc cho giảng viên.
Phonologically Based Reading Intervention for Undergraduate English Learners At-Risk of Reading Difficulties: A Pilot Study
Authors: Cook Michelle , Hughes Elizabeth
Published: April 2023

Researchers have reported that English language learners (ELLs) may be at risk of reading difficulties in thepostsecondary setting. Although some students may only require explicit content-related vocabulary instruction andsupport with comprehension strategies in order to enhance comprehension, others may benefit from targeted shortterm intervention in foundational reading skills. In this study, we examined whether a phonologically based readingintervention for undergraduate ELLs at-risk of reading difficulties would result in significant between-group differencesfor the proximal variables of decoding and sight word recognition and the distal variable of reading comprehension.This pilot quasi-experimental group design study involved 9 participants (treatment = 6/control = 3) from variousL1 backgrounds, including Chinese, Spanish, and Arabic. Effect sizes were calculated for the proximal variables usingmeasures of word attack and letter-word identification, and the distal variable based on a measure of passagecomprehension. Although a small and small-medium effect were calculated for the measures of word attack and letterword identification, respectively, no effect was found for the measure of passage comprehension. Implications relatedto intervention dosage and additional intervention components are discussed.
Value of Volunteer Leadership for University Students Formerly Enrolled in Prescribed Reading: An Anti-Deficit Model
Authors: Nelson Timothy
Published: April 2023

Local volunteer opportunities hold the potential for university students to develop as leaders and engaged membersof the academic community, but students taking prescribed (sometimes termed developmental education) coursesmay be overlooked as candidates for these kinds of opportunities. Taking an anti-deficit stance, university faculty maypromote student success by recruiting students from prescribed courses to participate in carefully-designed volunteerprograms. In this qualitative case study, I explored the perceptions of growth in the areas of academic engagementand leadership and the motivation to participate in future community volunteer service in student volunteers who hadpreviously been enrolled in prescribed reading courses. Three such university student volunteers reflected on theirexperience as leaders in a short-term academic outreach program for high school students. In open-ended surveyand interview responses, the university volunteers described their development of specific skills as well as changesin self-perception. Their responses indicated that they perceived the volunteer experience as effectual in all theinvestigated areas. Notably, they reported that serving as role models for youth encouraged specific academic habits.The study includes descriptions of the academic outreach program with supporting theory for its design because thecontext of the volunteer service cannot be separated from the findings. This study is a unique contribution to studentsuccess literature—there is no previous model linking students from prescribed courses with community volunteeropportunities.
Focus on Miniatures
Authors: Fraser Theresa
Published: April 2023

This is a reflection on the use of the miniature figure of the bridge. Written by Associate Editor, Theresa Fraser, of Canada, it provides thoughts on client use with comments from sand therapists across the globe.
Editor's Commentary
Authors: Homeyer Linda
Published: April 2023

This is the Editor's Commentary on Adlerian Sandtray Therapy as linked to the featured article by Terry Kottman.
Cidadania, participação e diálogo: o protagonismo juvenil como fundamento da formação crítica e da autonomia na educação
Authors: Cavalcanti Ana Claudia Dantas
Published: April 2023

O protagonismo juvenil entendido como base de uma formação crítica é parte de um contexto que inclui educação e cidadania. Nosso objetivo analisou a dimensão do protagonismo juvenil, tendo como base o diálogo em três percepções: da formação crítica do sujeito, da autonomia e da ação participativa. A educação na perspectiva da formação dialógica requer um modelo estado participativo com legislação e currículo que ofereça suporte ao desenvolvimento da aprendizagem nesta configuração. A concepção teórica da ação comunicativa baseia-se em Habermas (2012). A pesquisa apresentou método qualitativo, com processo técnico de análise de dados de revisão bibliográfica e busca em bases de dados on line, utilizando descritores, nos sites da Associação Nacional de Política e Administração da Educação - ANPAE, Associação Nacional de Pós-Graduação e Pesquisa em Educação - ANPED, Biblioteca Eletrônica Científica OnLine - Scielo e a Biblioteca Digital Brasileira de Teses e Dissertações – BDTD, no período de 2015 a 2020. Conclui-se que o protagonismo juvenil é entendido na razão inversa da formação crítica e autônoma. O modelo do estado gerencial efetivado no Brasil, não concretiza políticas que venham a contribuir para o desenvolvimento da formação juvenil gerando um princípio pedagógico de uma educação libertadora na perspectiva da cidadania, do diálogo e da ação participativa.
A sombra que Jack construiu
Authors: Veras Thor João de Sousa
Published: April 2023

Trata-se de uma “reconstrução com reserva genealógica” das bases historiográficas e ideológicas do liberalismo politico e dos desdobramentos teóricos da teoria da justiça de John Rawls, tendo como fio de condutor as contribuições da filósofa Katrina Forrester e de interlocutores acerca das fases de surgimento, consolidação e expansão da paisagem intelectual, para, em seguida, avaliar os potenciais e limites da sequência de acontecimentos que tornaram possível a tradição do liberalismo igualitário se estabelecer como paradigma incontornável, e não menos controverso, na história da filosofia moral e do pensamento político do século XX.
AWARENESS AND CONSCIOUSNESS ABOUT THE WORKING OF THE INTERNATIONAL CRIMINAL COURT
Authors: Das Prasoon
Published: April 2023

The International Criminal Court (ICC) plans to advance not only justice, but harmony too. It has been broadly censured for doing neither, yet it has to battle with some extreme auxiliary and political troubles: it has restricted assets, it faces institutional limitations, it is controlled by states, and it is reprimanded for a supposed selectivity in the manner it apportions equity. Notwithstanding, the ICC could contribute fundamentally to the advancement of worldwide equity and harmony, and majorly affect the anticipation of wrongdoing, since its indictments speak to an unmistakable danger to profoundly positioned people who submit genuine violations. This article focuses on the structure of the ICC. It contends that, the commitment of the ICC to international justice and harmony depends on its institutional force and the help it gets from states, all alone unprejudiced work, and in transit it is seen by expected hoodlums and casualties in the world.
GEOPOLITICAL SECURITY OF CONTEMPORARY RUSSIA: ESSENCE, STRUCTURE, FUNDAMENTALS OF MONITORING
Authors:   Geopolitical analysis center in Academy of geopolitical problems, Komleva Natalia A.
Published: April 2023

The article examines the essence of the geopolitical security phenomenon, studies the specifics of the geopolitical security of modern Russia. The main threats and vulnerabilities affecting the current state of Russia’s geopolitical security are highlighted. The author determines necessity, content and structure of the process of monitoring the geopolitical security of our country. As a part of monitoring the process of threats and vulnerabilities development, it is proposed to use such sociological technologies as content analysis and event analysis. The purpose of the study is to reveal the specifics of the phenomenon of geopolitical security of the Russian Federation and some ways to ensure it. The author employs systematic, comparative and phenomenological research methods. The author suggests definition of the “geopolitical security” concept as such a state of security of the geopolitical space of society from threats and vulnerabilities that it can ensure the unhindered survival and development of this very society. It is argued that geopolitical security is a systemic phenomenon, and its implementation is also a systemic phenomenon, for which constant monitoring of its current state is important. The author’s definition of the concept of “monitoring the state of geopolitical security” is given as a study of the process of formation, changes in time and ways of eliminating and/or preventing threats and vulnerabilities for the existence and development of this society.
A KINETIC STUDY OF THERMOCHEMICALLY BORIDED AISI 316L STAINLESS STEEL
Authors: BAŞMAN Gökhan , ARIKAN Mustafa Merih , ARISOY Cevat , ŞEŞEN Kelami
Published: April 2023

Biomaterials are used in different parts of human body as replacement implants in medical applications. An implant material should have high biocompatibility, corrosion and wear resistance, and suitable mechanical properties in terms of safety and long-service period. There are only a few biocompatible implant materials: AISI316L stainless steel is one of the materials used in this type of applications. They have relatively poor wear resistance. Boriding being a thermochemical diffusion treatment is one of the processes to improve their wear resistance. Borides are formed by introducing boron atoms by diffusion onto a substrate surface and they are non-oxide ceramics and could be very brittle. The growth kinetics of boride layer is analyzed by measuring depth of layers as a function of boriding time within a temperature range. In this study, the effects of Ekabor-2 bath on formation mechanism and properties of boride layer in thermochemical diffusion boriding of AISI316L stainless steel were investigated. Different temperatures and durations were applied in boriding operations and hardness, optical microscopy, XRD, EPMA and SEM studies were performed to detect the properties of boride layers. It was found that thickness of boride layer increased with increasing temperature and time; the basic phase in the boride layer formed was Fe2B and FeB phase also formed. It was also found that surface hardness values of borided materials increased depending on temperature and time of boriding process; surface hardness values of borided materials are approximately 10 times higher than surface hardness values of non-borided AISI316L stainless steel and formation activation energy of boride layer is 149.3 kjmol-1.
OPTIMAL DESIGN OF ORGANIC RANKINE CYCLE POWER PLANTS FOR EFFICIENT UTILIZATION of BIOMASS ENERGY IN NIGERIA
Authors: OYEKALE Joseph , JOHN Akpaduado
Published: April 2023

This study investigated the optimal design choice among four organic Rankine cycle (ORC) configurations for efficient utilization of solid biomass energy in Nigeria. Although vast opportunities exist for large-scale biomass power plants in the country, there has been little or no practical implementation yet, due to the limitation of technical know-how regarding thermodynamic conversion technologies. To bridge this gap, a thermodynamic optimization technique was applied in this study to the ORC. Specifically, the subcritical ORC (SUBORC), the regenerative subcritical ORC (SUBORC-REGEN), the supercritical ORC (SUPERORC), and the regenerative supercritical ORC (SUPERORC-REGEN) configurations were compared using established zero-dimensional optimization models implemented in MATLAB. Results showed that the SUPERORC-REGEN would be the most preferred choice amongst the options compared. Specifically, a palm kernel expeller (PKE) biomass fuel considered could yield about 1.98 MW of power at a thermal efficiency of about 28%. Additionally, it was obtained that the supercritical ORC would always outperform the subcritical types technically, with or without a regenerator. For the regenerative configurations, results showed that the supercritical ORC would generate 113 kW and 429 kW more net power than the subcritical ORC, respectively for n-pentane and n-butane working fluids. Similarly, the study reiterated that adopting a regenerative configuration would improve ORC performance. For instance, the SUPERORC-REGEN yielded 63% and 73% more power than the SUPERORC, respectively for n-pentane and n-butane working fluids. The practical economic implications of the different ORC configurations should be examined in future studies, alongside the investigation of exergy-based optimization potentials on component basis.
DESIGN AND ANALYSIS OF MULTI-BAND COMPACT MICROSTRIP ANTENNA IN GSM1900/WLAN/WiMAX/DSRC/X-BAND FREQUENCY BANDS FOR VEHICLE APPLICATIONS
Authors: YALDUZ Hüsnü , ÇİZMECİ Hüseyin
Published: April 2023

This study focuses the design and analysis of a compact, multi-band microstrip patch antenna for wireless communications operations. The design antenna exhibits distinct quad resonance frequency bands I from 1.879 GHz to 1.986 GHz, II from 3.1 GHz to 3.87 GHz, and III from 4.97 GHz to 6.515 GHz, IV from 7.26 GHz to 8.6 GHz, which covers GSM 1.900 GHz, WLAN (5.2/5.8 GHz), DSRC 5.9 GHz and WiMAX (3.5/5.5 GHz) bands. In addition, it can also support the X-band from 7.26 to 8.6 GHz. The antenna is designed on an inexpensive substrate of FR4 with dimensions of 36(L) × 25(W) mm2 and consists of two branches of curved strips for a quad-band response. The antenna is designed and analyzed using electromagnetic 3D computer simulation software. The designed antenna can provide advantages in GSM/WLAN/WiMAX/DSRC/X-band satellite applications for vehicle communication with four resonant frequency bands, nearly omnidirectional radiation characteristics, and acceptable gain.
POLYDATIN, A HERBAL BIOFLAVONOID, IS PROTECTIVE AGAINST CEREBRAL ISCHEMIA-REPERFUSION INJURY: MOLECULAR, BIOCHEMICAL AND HISTOLOGICAL DATA
Authors: ÇELİKÖZLÜ Saadet , ALTIKAT Said , ÖZYİĞİT Filiz , KÖKTÜRK Sibel , ÇELİKÖZLÜ Halit
Published: April 2023

This study aims to research the protective effects Polydatin have against cerebral ischemia/reperfusion damage. Polydatin is a natural polyphenic phytoalexin and which has strong antioxidant properties.
In the present study, 5 groups were prepared as control, sham, ischemia/reperfusion (IR), Polydatin 30 (Pol 30), and Polydatin 60 (Pol 60). The four-vessel occlusion model was used to induce ischemia. Polydatin was injected intraperitoneally 30 minutes before ischemia. Hematoxylin Eosin staining were applied for histopathological study, SOD, CAT, and MDA levels determined, and TNF-α mRNA expression levels were measured by the RT-qPCR technique in brain tissue. According to the results, a serious loss of neurons in the CA 1 region of the hippocampus was observed in the IR group. Neuronal damage in the hippocampus decreased and the number of neurons increased significantly in the Pol 60 group compared to the IR group. CAT and SOD levels were reduced, and the MDA level rose in the IR group. In Pol 60 and Pol 30 groups, an increase was observed in the CAT and SOD levels, a decrease was observed in the MDA and total protein levels compared to the IR group. The amount of TNF-α mRNA expression in the brain tissues of the IR group was significantly higher compared to the control group. In the Pol 60 group, mRNA expression level decreased significantly compared to the IR group. In conclusion, the increase in MDA, decrease in SOD and CAT values, increase in TNF-α gene mRNA expression, and histological damage in the brain because of cerebral ischemia/reperfusion in rats were restored to normal levels with 30 and 60 mg/kg polydatin administration as protective before ischemia. Especially at 60 mg/kg polydatin supplementation with antioxidant properties has a neuroprotective effect against oxidative stress damage caused by cerebral ischemia/reperfusion.
Identification of Pacejka model parameters of a light commercial vehicle tire for dynamic research
Authors: Toropov Eugeny , Vashurin Andrey , Tumasov Anton , Butin Danila , Stepanov Evgeniy
Published: April 2023

This article is devoted to the research of the interaction of the wheel of a GAZ light commercial vehicle with a hard supporting surface. The relevance of this problem is due to the need to adequately reproduce the force reactions acting on the tire in the contact patch, when modelling the vehicle dynamics. High similarity of the real process and its modelling are guaranteed if there is a significant empirical data set for a particular tire model, which can be ensured only by the results of field tests. Specialists from Nizhniy Novgorod State Technical University have developed a schematic diagram of a road measuring unit, a test methodology and built testing unit as well as conducted full-scale tests. The experiment was conducted in the auto racing track at an ambient air temperature of 20 °C on a dry road asphalt surface with a high friction coefficient (0.4 - 0.8). The resulting array of experimental data was processed and presented in numerical trigonometric polynomials form (PAC 2002). The table comparing theoretical and experimental values presented in the results of this article confirms the high level of convergence. The maximum discrepancy in absolute value does not exceed 5%.
Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading
Authors: Porter Hayley , Li Yang , Neguembor Maria Victoria , Beltran Manuel , Varsally Wazeer , Martin Laura , Cornejo Manuel Tavares , Pezić Dubravka , Bhamra Amandeep , Surinova Silvia , Jenner Richard G , Cosma Maria Pia , Hadjur Suzana
Published: April 2023

Most studies of cohesin function consider the Stromalin Antigen (STAG/SA) proteins as core complex members given their ubiquitous interaction with the cohesin ring. Here, we provide functional data to support the notion that the SA subunit is not a mere passenger in this structure, but instead plays a key role in the localization of cohesin to diverse biological processes and promotes loading of the complex at these sites. We show that in cells acutely depleted for RAD21, SA proteins remain bound to chromatin, cluster in 3D and interact with CTCF, as well as with a wide range of RNA binding proteins involved in multiple RNA processing mechanisms. Accordingly, SA proteins interact with RNA, and R-loops, even in the absence of cohesin. Our results place SA1 on chromatin upstream of the cohesin ring and reveal a role for SA1 in cohesin loading which is independent of NIPBL, the canonical cohesin loader. We propose that SA1 takes advantage of structural R-loop platforms to link cohesin loading and chromatin structure with diverse functions. Since SA proteins are pan-cancer targets, and R-loops play an increasingly prevalent role in cancer biology, our results have important implications for the mechanistic understanding of SA proteins in cancer and disease.
Spatiotemporal tissue maturation of thalamocortical pathways in the human fetal brain
Authors: Wilson Siân , Pietsch Maximilian , Cordero-Grande Lucilio , Christiaens Daan , Uus Alena , Karolis Vyacheslav R , Kyriakopoulou Vanessa , Colford Kathleen , Price Anthony N , Hutter Jana , Rutherford Mary A , Hughes Emer J , Counsell Serena J , Tournier Jacques-Donald , Hajnal Joseph V , Edwards A David , O’Muircheartaigh Jonathan , Arichi Tomoki
Published: April 2023

The development of connectivity between the thalamus and maturing cortex is a fundamental process in the second half of human gestation, establishing the neural circuits that are the basis for several important brain functions. In this study, we acquired high-resolution in utero diffusion magnetic resonance imaging (MRI) from 140 fetuses as part of the Developing Human Connectome Project, to examine the emergence of thalamocortical white matter over the second to third trimester. We delineate developing thalamocortical pathways and parcellate the fetal thalamus according to its cortical connectivity using diffusion tractography. We then quantify microstructural tissue components along the tracts in fetal compartments that are critical substrates for white matter maturation, such as the subplate and intermediate zone. We identify patterns of change in the diffusion metrics that reflect critical neurobiological transitions occurring in the second to third trimester, such as the disassembly of radial glial scaffolding and the lamination of the cortical plate. These maturational trajectories of MR signal in transient fetal compartments provide a normative reference to complement histological knowledge, facilitating future studies to establish how developmental disruptions in these regions contribute to pathophysiology.
A frameshift in Yersinia pestis rcsD alters canonical Rcs signalling to preserve flea-mammal plague transmission cycles
Authors: Guo Xiao-Peng , Yan Hai-Qin , Yang Wenhui , Yin Zhe , Vadyvaloo Viveka , Zhou Dongsheng , Sun Yi-Cheng
Published: April 2023

Multiple genetic changes in the enteric pathogen Yersinia pseudotuberculosis have driven the emergence of Yesinia pestis, the arthropod-borne, etiological agent of plague. These include developing the capacity for biofilm-dependent blockage of the flea foregut to enable transmission by flea bite. Previously, we showed that pseudogenization of rcsA, encoding a component of the Rcs signalling pathway, is an important evolutionary step facilitating Y. pestis flea-borne transmission. Additionally, rcsD, another important gene in the Rcs system, harbours a frameshift mutation. Here, we demonstrated that this rcsD mutation resulted in production of a small protein composing the C-terminal RcsD histidine-phosphotransferase domain (designated RcsD-Hpt) and full-length RcsD. Genetic analysis revealed that the rcsD frameshift mutation followed the emergence of rcsA pseudogenization. It further altered the canonical Rcs phosphorylation signal cascade, fine-tuning biofilm production to be conducive with retention of the pgm locus in modern lineages of Y. pestis. Taken together, our findings suggest that a frameshift mutation in rcsD is an important evolutionary step that fine-tuned biofilm production to ensure perpetuation of flea-mammal plague transmission cycles.
Siberi eestlaste lapse sünniga seotud kombestik ja sünnituslood
Authors:   Estonian Folklore Archives, Estonian Literary Museum, Estonia, Korb Anu
Published: April 2023

To study the childbirth customs and stories of Siberian Estonians, I used conversations and interviews conducted in various Siberian Estonian communities during the fieldwork of the Estonian Folklore Archives between 1991 and 2013, as well as the memories of Estonians who had been born in the Estonian settlements in Siberia and repatriated during or after the Second World War. As information related to childbirth customs is very much a private matter, the collection of such material during fieldwork in Siberia was somewhat limited due to short time and the guest status of the collectors. Women born in the 1910s–1930s who had experience of giving birth at home were more likely to share information. Siberian Estonians, who were born and raised in village communities with a rich heritage, share both personal and community experiences in their childbirth stories. Although the triumph of state medicine, with its small hospitals, had reached Siberian villages after the end of the Second World War, the initially trained medical professionals were met with mistrust and alienation. Village midwives were still respected, and villages adhered to many of the old beliefs about childbirth, as childbirth was controlled by the village community. Over time, giving birth under the supervision of hospital-trained medical staff became the norm. So, the need for village midwives has disappeared, and some of the traditions and customs associated with childbirth have been forgotten. At the same time, traditions related to the pre-pregnancy period and some childbirth stories helping to raise community awareness have remained very much alive.