bluuebunny/crossref_metadata_2025 huggingface dataset:
Mentoring of Mekarsaluyu Women Farmers Group as MSMEs Producers of One Village One Product in Utilizing Digital Marketing as a Promotional Media
Authors: Wardhana Adhitya Ikhsani , Silaningsih Endang , Suryani Danu , Yuningsih Erni , Maulana Lucky Hikmat
Published: February 2025

BARAYU MSMEs is an OVOP producer of MSMEs in Margaluyu Village that needs help increasing its income due to the marketing methods used. For this reason, business actors need changes in the promotion model to maintain their business. Technological developments have made social media widely used, opening up opportunities for business actors as a medium for product promotion. This service aims to provide knowledge and promote products, assist in creating trademarks, MSMEs logos, websites, and skills for MSMEs in designing product promotions on social media and increasing product sales. Assistance uses the Participatory Action Research (PAR) method: observation, interviews, discussions, assistance, and Output. The results obtained after carrying out this service are increased knowledge and Understanding of BARAYU MSMEs owners regarding the existence and potential of social media in promoting products, the creation of the brand name "BARAYU," the creation of a logo and website as well as MSMEs social media accounts, increased skills of MSMEs owners in using social media as a promotional medium, and increasing the number of product sales.
Analysis of Smoked Fish Processed Businesses on the Welfare of Coastal Communities in Lahewa District, North Nias District
Authors: Gulo Ahmad Jumadin , Lubis Irsad
Published: February 2025

Management of marine resources is still traditional, and community knowledge that can only be passed down from generation to generation has caused the people in Siheneasi Village to go into a cycle of poverty. The many daily needs exacerbate this condition, including children's education costs, health, and others. Living conditions still need to be fully controlled by society itself. In other words, life is still not sufficient. Sufficient in terms of children's education, health, and even daily costs. The mediocre income relies on results from the sea, which are sometimes uncertain, and unpredictable weather conditions that prevent coastal communities in Siheneasi Village from going to sea because they fear the high risks. This research aims to find out whether potential, capital, consumption, distribution, labor, technology, income, and education have a significant effect on increasing the welfare of coastal communities in Lahewa District and to find out relevant factors that have a significant influence on increasing the welfare of coastal communities in Lahewa District. What was studied was whether potential, capital, consumption, distribution, labor, technology, income, and education significantly influenced the welfare of coastal communities in Lahewa District and relevant factors significantly influenced the welfare of coastal communities in Lahewa District. A total sample of 207 respondents was collected by distributing questionnaires and processing data using Confirmatory Factor Analysis (CFA) and Multiple Linear Regression. The results of the Confirmatory Factor Analysis (CFA) test in the KMO and Bartlett's test tables show that income, education, and potential factors are significant for community welfare in Siheneasi Village, Lahewa District. In contrast, capital, distribution, labor, and technology factors negatively or insignificantly affect the community's welfare in Siheneasi Village, Lahewa District. Moreover, multiple linear regression testing results show partial hypothesis test results for consumption, income, education, and significant potential for community welfare in Siheneasi Village, Lahewa District.
The Impact of Poverty, Education Spending, and Village Funds on the Human Capital Index in the Nias Islands
Authors: Berutu Saiful Ragatna , Lubis Irsad
Published: February 2025

The Human Development Index can be used as an indicator of successful development in a country or region. In 2023, the lowest Human Development Index in North Sumatra Province was in the Nias Islands, namely West Nias Regency (63.70), South Nias Regency (64.13), Nias Regency (64.56), and North Nias Regency (64.64). Only Gunungsitoli City ranks in the lowest 10 out of 33 regencies/cities with an index of 70.68. This study aims to determine whether Poverty, Education Expenditure, and Village Funds have an impact on the Human Development Index in the Nias Islands. The results showed that partially Poverty has a negative and significant impact, Education Expenditure has a positive but insignificant impact, and Village Funds have a positive and significant impact on the Human Development Index in the Nias Islands. Poverty, education expenditure, and village funds simultaneously have a significant impact on the Human Development Index. Poverty, education expenditure, and village funds can explain the Human Development Index by 93.766%. The remaining 6.234% is accompanied by other variables that are not included in the object of this study. Therefore, the Government should create programs for poverty alleviation and optimize Education Expenditure and Village Funds to increase the Human Development Index in the Nias Islands.
Execution of Fiduciary Guarantees Post 2019 MK (Constitutional Court) Ruling
Authors: Zikry Bagas Bi , Harahap Mhd. Yadi , Saragih Nabila Fadiyah Shafa , Harahap Kholid , Desky Saddam Pardamean , Wahyudi Wahyudi
Published: February 2025

Fiduciary guarantee is a language that is often used in Indonesian and also in Law No. 42 of 1999. Collateral is an asset owned by a borrower to be used as collateral or deposit for the loan he receives which is handed over to the lender. The transfer of an ownership right to an object with a sense of mutual trust on mutually agreed terms, namely to an object whose ownership rights are transferred remains under the control of the original owner of the object. Historically, fiduciary institutions have been established since Roman times. As history progressed, Roman law also developed until the emergence of pawning and mortgage institutions. This causes the role of fiduciary institutions as debt collateral to begin to diminish and their existence has also disappeared. This happened after the classical era under the leadership of Justianus.
Efforts to Increase New Students Through Socialization of Economics Majors and Job Opportunities for High School Students
Authors: Parasan Pradipta Mandasari , Kolinug Ferly Christian , Supriyanto Supriyanto
Published: February 2025

In an era full of competition like today requires us to have more skills, especially in the field of science and technology, because it is our provision in entering the world of work and can compete, one of the education that is expected to be taken is higher education at the university level. In North Sulawesi, one of the popular universities is Manado State University where there are 7 faculties including the Faculty of Economics and Business with a major in Economics, increasing the number of new students in the Department of Economics is one of the focuses in the development of higher education institutions. One of the efforts made is through socialization activities targeting high school students. This activity aims to provide a comprehensive understanding of the Department of Economics, including the curriculum, study program excellence, and career opportunities that can be accessed by graduates. Participants who participated in this activity were students of Class VII of SMA Negeri 1 Airmadidi. This socialization was successfully carried out as seen from the enthusiasm of students in conducting discussions and questions and answers, and many students were finally interested in continuing their education to universities, especially to the Department of Economics.
Exploring the Relationship between Humane Education and Active Citizenship in Early Childhood Education
Authors: Pitsou Charikleia , Dionysopoulou Eirini
Published: February 2025

This paper examines the intersection of humane education and active citizenship, emphasizing how nurturing empathy, critical thinking, and ethical decision-making through education fosters active citizenship. Humane education, which incorporates themes of environmental stewardship, social justice, animal welfare, and global interdependence, serves as a transformative tool for cultivating active, informed, and ethical citizens from an early age. The education of individuals from their earliest years with universal and democratic values, the principles of human rights, and a clear orientation toward respect for all living beings can contribute, on the one hand, to shaping active future citizens who prioritize the right to life and, on the other hand, to the humanization of the individual and the effort to establish lasting peace worldwide. Only within an educational environment characterized by a spirit of solidarity, mutual understanding, and respect—not only for all people but also for all living organisms—can peaceful coexistence truly be achieved, replacing the prevailing paradigm of human dominance over nature and over humanity itself. This article combines theoretical frameworks, empirical evidence, and pedagogical practices with early childhood education to illustrate the potential of humane education in advancing active citizenship.
ASSESSING THE STANDARD OF CARE OF DOCTORS IN EMERGENCY DEPARTMENTS
Authors: Yaakob Haniwarda
Published: February 2025

Working in emergency departments appears to be challenging as the doctors stationed here encounter obstacles that may not be faced by other doctors. This includes the need to attend to a high number of patients, the lack of manpower and resources, as well as the pressing situation of being in an emergency. This condition may be more apparent in public hospitals that are usually overcrowded with patients with various illnesses that require urgent treatment. Occasionally, claims of medical negligence have been filed against doctors and hospitals by patients seeking medical treatment in emergency departments. An issue, therefore, arises on the standard of care required of doctors as has been imposed by the law on working in emergency departments. The question is whether the calamitous situation that doctors in emergency departments encounter is acknowledged by the law as a possible defence against the allegation of negligence in Malaysia. From the cases analysed, it is concluded that doctors in emergency departments are expected to exercise the skill of any other reasonable competent doctor in similar circumstances. As such, doctors and hospitals should strive to provide the best medical treatments according to the situations of each case in order to avoid liability in negligence. It is hoped that the findings of this research would assist doctors working in emergency departments in discharging their daily duties according to the standards imposed by law. To fulfil its objective, this research employs legal and doctrinal methods in which the analysis and arguments have been based on the written literature, which has been mainly case laws from Malaysia and the United Kingdom, as well as textbooks and journals.
DATA PROTECTION CHALLENGES IN SMART CITIES: AN EXAMINATION OF THE MALAYSIAN LEGAL FRAMEWORK
Authors: Nourooz Pour Hesam
Published: February 2025

Smart cities are the future of urban development as they incorporate state of the art technology to enhance the living standards of the citizens. However, these advances have real challenges in terms of data protection, more so in countries like Malaysia, where the legal aspects are still developing. This paper will critically analyze Malaysia's legal framework for data protection in the context of the Malaysian Smart City Framework and its data collection and processing practices. In this paper, the three fundamental principles of data protection, namely necessity, consent and safeguards will be examined. Using a comparative law approach, this research compares Malaysian laws with international standards, in particular the General Data Protection Regulation of the EU. This comparison shows some serious gaps and hurdles in Malaysia's approach, particularly with regard to protection from automated decision-making and surveillance technology. This research will also show that Malaysia must improve its legislation to ensure privacy will not be invaded when the smart city technologies are have already become so widespread. The findings advocate the need for Malaysian laws and policies to be positively realigned with technology to create a privacy-aware model and fit for purpose for the shifting requirements of smart urban arenas.
An Analysis of the Use of Symbolism in Al Chemist by Paulo Coelho
Authors: Marium Bushra  , Saira Parveen  , Zeba Quamer  , Sania Rizwan
Published: February 2025

This research aims to read the novel closely and analyze Paulo Coelho's Alchemist and its symbols. Using Peirce's semiotic analysis approach, the research will assign the symbols widely accepted meanings and evaluate how these "accepted" meanings affect the same novel. The purpose of this research is to describe the personal legend concept of journeys that are both physical and psychological at the same time. In this novel, symbolism guides the protagonist’s inner journeys, which form a significant part of the novel. While these novels are said to appear inspirational for depressed souls with a profound philosophical and spiritual dilemma, the study of symbols found in these novels gives implications for future research.
Correlation between Axial Length and Progression of Diabetic Retinopathy: Axial Length and Diabetic Retinopathy Progression
Authors: Eldressi Rana , Elshokri Yasmena
Published: February 2025

Diabetes mellites (DM) can cause various eye issues, like a higher chance of getting cataracts. But the most common and serious problem is diabetic retinopathy. Some researches indicate that with every additional millimeter in axial length, there is a 19% reduction in the prevalence of DR. On the other hand, another study conducted to investigate the relationship between axial length and retinal involvement in patients with diabetes show different result that patients with retinopathy had shorter axial lengths than did patients without retinopathy. This study aims to investigate the potential correlation between ocular axial length and the progression of diabetic retinopathy in individuals with diabetes.  A prospective cross-sectional randomized study designed to evaluate the relationship between axial length and the diabetic retinopathy (DR) for 105 eyes diagnosed with Diabetes Mellitus and having Diabetic Retinopathy in any stage, all case was attending and seeking routine eye examinations at Benghazi Eye Teaching Hospital. They underwent a complete ophthalmic evaluation, by slit lamp bio-microscopy, and a detailed fundus examination. Axial length measurement for all eyes using an A-scan Ultrasonography 12 Megahertz (MHz) focused probe (Ellex Eye Cubed i3 Ultrasound).  In our investigation concerning patients diagnosed with diabetes, When analyzing the relationship between the duration of diabetes in years and the progression of diabetic retinopathy (DR), it was observed that as the duration of diabetes increases, the severity of DR also tends to increase. And we observed a heightened prevalence of diabetic retinopathy (DR) among those with shorter ocular axial lengths. significant at a 0.01 level, underscores an inverse association between ocular axial length and DR prevalence.
Impact of financial statements information on market share price of listed insurance firms in Nigeria
Authors: Salman Ramat , Abogun Segun , Lambo Isaac Adebukola , Yunus Abdulrasheed Bolaji , Sanni Peter Ade
Published: February 2025

In emerging economies, there is an issue of relevant information for investors’ decision.  Therefore, this study is carried out to determine the value relevance of financial statements information on Market Share Price of Nigerian listed insurance firms as at 31st December, 2022. Positivism methodology was adopted and as such, ex-post facto design was employed. Consequently, secondary data was used for this research work, obtained from the published annual reports and accounts of the selected insurance firms. The Panel data regression was used to analyze the data. The study found that both dividend per share and solvency margin ratio have positive and significant impact on market price per share (p-value > 5% level of significance). On the other hand, book value per share and earnings per share were found to have insignificant impact on market price per share (p-value > 5% level of significance). The study concludes that dividend per share and solvency margin ratio influenced market price per share of the selected companies in Nigeria and thus recommends that listed insurance companies should do more towards generating adequate profit that will enable payment of dividend to investors and to pay insurers their probable claims whenever the need arises.
Sustainable HR Practices: Examining the Connection Between Organizational Resilience and Green HRM in the Hospitality Sector
Authors: Adhika I Nyoman Resa
Published: February 2025

Organizations must adopt sustainable human resource practices (SHRP) to meet the difficulties of global sustainability. According to data published by the Official Statistics News, the number of foreign visitors to the province of Bali fluctuated. From July 2023 to November 2023, it dropped from 545,272 to 397,552, then increased to 502,830 until April 2024. All stakeholders in Bali Province, especially the hotel industry, must be able to pay attention to changes in the quantity of tourists visiting. This study investigates the effects of organizational resilience and Green Human Resource Management (GHRM) on SHRP in the hotel sector. 120 personnel from five-star hotels participated in the survey, which was carried out in Bali. The research problem was addressed with the aid of SEM PLS. The findings demonstrated that organizational resilience and GHRM significantly and favorably affect SHRP. According to the findings, the association is somewhat mediated by organizational resilience. This implies that the implementation of sustainable HR policies will be improved with the help of a strong GHRM policy and increased organizational resilience. The study’s practical implications include the need for hotels and other hospitality-related enterprises in Bali to implement more extensive GHRM policies, including environmentally-based performance evaluation, sustainability-focused training, and green hiring.
Menyingkap Representasi Perempuan Dan Simbol Agama Dalam Poster Film Horor Indonesia: Melampaui Stereotip
Authors: Pratiwi Sekar , Fauziyyah Ifa Bilqiis , Wahyudi Luqman
Published: February 2025

The Indonesian religious-themed horror film industry, as exemplified by Kiblat, Siksa Neraka, and Sijjin, leverages religious symbols to evoke fear and tension, presenting a stark contrast between sacredness and horror. However, this approach has sparked public controversy, with many perceiving it as a desecration of religious sanctity, leading to protests and boycotts that underscore the tension between artistic expression and religious values in Indonesian society. Furthermore, the portrayal of women in these films' posters often reinforces patriarchal stereotypes by depicting them as victims or objects of violence, perpetuating narratives of female subordination and hindering progress toward gender equality. Through Stuart Hall's Representation Theory, this study analyzes the visual and ideological construction of religious symbols and female figures in Indonesian horror film posters, exploring their denotative and connotative meanings to understand the genre's role in shaping social discourse on religion and gender within Indonesia's cultural context.
Negoisasi Penyajian Karya Seni Mural Di Yogyakarta (Komunitas Jogja Mural Forum)
Authors: Yanuar Ikhsan Pamuji  , Kusuma Alfiandi Eka , Bagja Bachrul Restu
Published: February 2025

Seni ruang publik merupakan bentuk ekspresi artistik yang hadir di tengah masyarakat, merespons dan melebur dengan kondisi sosial yang berkembang. Di Indonesia, khususnya Yogyakarta, seni mural menjadi salah satu bentuk seni ruang publik yang berkembang pesat. Perkembangan seni mural di Yogyakarta tidak dapat dipisahkan dari peran penting yang dimainkan oleh Jogja Mural Forum (JMF), sebuah inisiatif yang bertujuan untuk memperkenalkan dan mengembangkan seni mural melalui pendekatan partisipatoris. JMF mengajak masyarakat Yogyakarta untuk berperan langsung dalam proses penciptaan mural, baik sebagai seniman maupun sebagai bagian dari audiens yang turut merasakan dampak sosial dan kultural yang ditimbulkan. Keterlibatan aktif masyarakat dalam seni mural ini tidak hanya memperkaya apresiasi terhadap karya seni, tetapi juga membentuk ruang interaksi sosial yang baru, di mana seni berfungsi sebagai media komunikasi antara individu dan komunitas. Dengan demikian, seni mural di Yogyakarta, melalui proyek JMF, tidak hanya menjadi sarana ekspresi artistik, tetapi juga mencerminkan dinamika sosial dan budaya masyarakat setempat.
Depuración de aguas servidas. Estudio de caso en San Isidro de Patulú.
Authors: Frías Torres Alex Xavier , Muyulema Muyulema Danny Germán , Núñez Aldás Galo Wilfrido , Chusin Vega Edgar Patricio
Published: February 2025

El presente estudio tiene como objetivo el diseño de una Planta de Tratamiento de Aguas Residuales (PTAR) para las comunidades Santa Rosa y San Francisco de la parroquia San Isidro de Patulú, con el fin de reducir la carga contaminante de las aguas residuales y garantizar su cumplimiento con los límites máximos permisibles establecidos por la normativa vigente. Se realizó una caracterización del agua residual en la que se identificaron parámetros físico-químicos clave, destacándose la Demanda Química de Oxígeno (DQO), la Demanda Bioquímica de Oxígeno (DBO5) y el Nitrógeno Total como principales contaminantes que exceden los límites normativos. Con base en estos resultados, se diseñó una línea de tratamiento eficiente que permite una reducción significativa de los contaminantes presentes en el agua residual. La evaluación de la eficiencia del tratamiento implementado demostró que los valores de DQO, DBO5 y Nitrógeno Total fueron reducidos a niveles dentro de los límites permisibles, permitiendo que el agua tratada pueda ser descargada al río Guano. Se diseñó una Planta de Tratamiento de Aguas Residuales (PTAR) que incluye procesos de cribado, seguidos de dos tanques de sedimentación, un filtro anaeróbico de flujo ascendente (FAFA) y un lecho de secado para la gestión de los lodos, garantizando que la descarga final cumpla con los requisitos ambientales establecidos. Este estudio proporciona una base técnica y científica para la implementación de una PTAR funcional y eficiente en la zona de estudio, contribuyendo a la mitigación del impacto ambiental generado por las aguas residuales y promoviendo el uso sostenible de los recursos hídricos.
Patterns and predictors of intimate partner violence among married women living in urban informal settlements of Bangladesh: Cross-sectional survey
Authors: Shiblee Shafayatul Islam , Rashid Md. Harunor
Published: February 2025

Background: Despite legal and policy proscriptions, intimate partner violence remains a pervasive issue worldwide, with particularly severe implications for marginalised and vulnerable women. In Bangladesh, women living in urban slums may face increased risks, but evidence remains limited. This study aimed to address this knowledge gap.
Methods: Cross-sectional survey was done among ever-married women resident (aged 18 years or older) in slums-dwelling in Dhaka North, Dhaka South and Gazipur. Data was collected using face-to-face interview on four types of intimate partner violence: physical, sexual, emotional and economic. Univariate and multivariate logistic regression analyses were done to explore the association between the violence outcome variables and sociodemographic characteristics.
Results: Six hundred seven women participated in the survey. The overall level of any form of life-time violence was 82%. Physical violence was most reported (66%), followed by economic (47%), sexual (44%), and emotional (38%). Uneducated women, and those whose husbands were uneducated, faced particularly high risks of violence. Gazipur stood out as an area with higher intimate partner violence than other slum areas. Working women also experienced more life-time violence than non-working women.
Conclusion: Urban slum women face high levels of violence in Dhaka and Gazipur. Policy level interventions, workplace-based actions and community-level measures should be taken to curb this epidemic. Specific steps should be taken to increase awareness related to intimate partner violence, and improve attitudes towards gender roles among women residing in urban slums.
Pasture ryegrass (Lolium perenne L.) is a universal crop for forage production in the European part of Russia
Authors: Kostenko Sergey , Kostenko Natalia , Vasil'eva Ol'ga , USOL'CEVA Elena
Published: February 2025

Grassland ryegrass is often the main forage crop in many countries of Europe and North America, and it has also found its second homeland in New Zealand, and some countries of South America. In Russia, historically, this crop was grown in the Northwestern regions, which are characterized by sufficient moisture and mild winters. Already in the XIX century, this culture was already known in the Baltic provinces and in St. Petersburg. However, in the territory of modern Russia, this culture began to spread widely only from the 70s of the last century, when the first varieties of Veya, Morshanskiy1, Pskovskiy mestnyy appeared [1].
Microbiome structure in healthy and pregnant women and importance of vaginal dysbiosis in spontaneous abortion
Authors: Eslami Majid , Naderian Ramtin , Ahmadpour Ariyan , Shushtari Ali , Maleki Sahar , Mohammadian Parham , Amiri Arvin , Janbazi Maryam , Memarian Mohammad , Yousefi Bahman
Published: February 2025

The vaginal microbiome of healthy women is dominated by Lactobacillus spp. A variety of illnesses, such as vaginosis, sexually transmitted infections (STIs), failed implantation, premature birth (PTB), and preterm pre-labor membrane rupture, are brought on by an unbalanced microbiota. Pregnancy is associated with a decrease in the metabolic capacity of the vaginal resident microbiome, which is consistent with a change to a less complex Lactobacillus-dominated microbiome. Age, race, sexual intercourse, smoking, IUD, contraception, lifestyle, and diet all affect the makeup of the vaginal microbiome. Moreover, physiological events including menarche, the menstrual cycle, pregnancy, menopause, and other hormonal changes have an impact on the vaginal microbiome. The vaginal microbiome is significantly disrupted by the menstrual cycle, with significant changes toward a more varied microbiota occurring around menstruation. Several major factors maintain or disrupt the vaginal microbiome including ethnic group, menstruation cycle, and pregnancy which are discussed in this section. In the index pregnancy, the vaginal microbiota of women who had already given birth, or had just experienced an induced or spontaneous abortion, was qualitatively and quantitatively different from that of women who were having their first child. Early pregnancy vaginal microbiome depletion is a risk factor for early pregnancy miscarriage. Although, early pregnancy miscarriage is not always caused by a high bacterial diversity and quantity of lactobacilli. Lactobacillus protects against pathogens through the production of antibacterial compounds such as lactic acid and bacteriocins.
Best practices in public risk communication during enteric illness outbreak investigations: a scoping review
Authors: Mucević Hana , McWhirter Jennifer E. , Macleod Jillian , Shereefdeen Hisba , MacKay Melissa , Cheng Leslie , Phypers Melissa , Grant Lauren E.
Published: February 2025

Introduction

Public risk communication is intended to inform and protect the health of individuals during enteric illness outbreaks. However, there is limited practical research that assesses the effectiveness of communication during outbreaks. The aim of this study was to identify best practices in public risk communication during enteric illness outbreak investigations.

Methods

A scoping review of five bibliographic databases and gray literature was conducted to identify studies that described public communication during foodborne, waterborne, or enteric zoonotic outbreaks. Eligibility criteria were applied to citations and then full text by two independent reviewers. Data from included studies was extracted and synthesized into categories. Evidence adequacy and agreement were assessed and used to assign an overall level of confidence for each best practice.

Results

In total, 25 studies were included with most studies occurring in North America and Western Europe. Seven principles, nine practices, and eight platforms were identified. Of these, six principles, four practices, and two platforms received a high confidence rating in their overall effectiveness.

Discussion

Effective risk communication during enteric illness outbreak investigations requires public health authorities to identify, characterize, tailor information to, and meaningfully engage with their target audiences, build relationships and collaborate with media outlets, and maintain and increase credibility to deliver trustworthy risk communication messages.
Ideology, resistance, and sociopolitical dynamics in Indonesia: media narratives and resistance discourses on the chairman of the corruption eradication commission’s corruption case
Authors: Qathrunnada Zalfa , Nugroho Catur , Yusanto Freddy , Wulandari Astri , Wulan Roro Retno
Published: February 2025

Indonesia’s Corruption Eradication Commission (KPK) is an anti-graft organization established in 2003 that plays a vital role in preventing and eradicating corrupt practices in Indonesia. Ironically, KPK Chairman 2019–2023, Firli Bahuri, was named a corruption suspect on November 22, 2023. The incident of naming the KPK Chairman as a suspect by the police caused conflict between KPK and the Police Department and attracted the media’s attention. This article aims to discover how DetikCom, Kompas.com, and Tempo.co, produce texts and discourses of resistance by the KPK Chairman against being named a suspect. Researchers also tried to uncover the ideology and interests of the media in the production of corruption discourse in Indonesia based on the external context of media and politics in Indonesia. The author used the text analysis method with Norman Fairclough’s Critical Discourse Analysis to analyze 18 media texts. The researcher found that the resistance discourse packaged by Detikcom online media tends to support the law enforcement narrative by providing more space for the Police Department to convey evidence and processes carried out. Kompas.com emphasizes that Firli has the right to file a pretrial and that the legal process must be respected, giving the impression that the media respects Firli’s legal rights. Tempo.co emphasized the case’s legal aspects and processes, including Firli Bahuri’s pretrial submission. At the sociocultural level, there is a relationship between corruption cases in Indonesia, government policies, and public responses to the conflict discourse over the KPK chairman.
The Aragonese rural school in intercultural contexts: a basic of social justice and territorial equity in resilient Spain
Authors: Domingo Cebrián Virginia , Nolasco Hernández Alberto , Lorenzo Lacruz Juan , Gracia Sánchez Laura
Published: February 2025

The main characteristics of rural schools include their intercultural context and diversity, making them an inclusive reference. This diversity fosters positive relationships between the school and its environment, enhancing the teaching-learning process. This article presents partial results from a project by the Ministry of Science and Innovation of Spain titled “Rural schools: a basic service for social justice and territorial equity in sparsely populated Spain” (PID2020-115880RB-100). Using stratified random sampling with proportional allocation, 101 rural schools in Aragon participated, represented by 61 teachers who provided data through the “Rural school and territorial dimension” questionnaire. The questionnaire gathered information on various educational projects implemented in collaboration with other institutions to promote territorial development and address the challenges and needs of rural areas. The results showed that 90.1% of the projects focus on developing collective identity and a sense of belonging, providing services to the community, fixing and/or rooting the population, and responding to shared needs. These findings highlight the role of rural schools in cultural integration, inclusion, and specific support to ensure that all students and their families feel valued and an integral part of the community.
The impact of ESG performance on the financial performance of companies: evidence from China's Shanghai and Shenzhen A-share listed companies
Authors: Zhang Li-Sen
Published: February 2025

Introduction

Corporate ESG (Environmental, Social, and Governance) performance has become a key factor in achieving sustainable and healthy development, as well as enhancing financial performance. This study examines the impact of corporate ESG performance on financial performance in the Chinese market, providing empirical evidence for its influence and implications.

Methods

Using panel data from Chinese A-share listed companies on the Shanghai and Shenzhen stock exchanges from 2009 to 2022, this study employs econometric models to analyze the relationship between ESG performance and financial performance. Endogeneity and robustness tests are conducted to ensure result reliability. Additionally, moderating effects and heterogeneity analyses are performed to explore influencing factors.

Results

The findings indicate that corporate ESG performance significantly enhances financial performance. This conclusion holds after accounting for endogeneity and robustness tests. Further analysis reveals that financing constraints positively moderate the ESG-financial performance relationship, whereas corporate innovation focus has a negative moderating effect. Heterogeneity analysis shows that the positive impact of ESG performance is more pronounced in enterprises located in eastern regions, state-owned enterprises, and high-pollution industries.

Discussion

This study provides empirical evidence from China, demonstrating the critical role of ESG in corporate financial performance. The results offer valuable insights for policymakers, investors, and corporate managers aiming to promote sustainable development and optimize investment strategies.
AlphaBoot: accelerated container cold start using SmartNICs
Authors: Galvankar Shaunak , Choi Sean
Published: February 2025

Scalability and flexibility of modern cloud application can be mainly attributed to virtual machines (VMs) and containers, where virtual machines are isolated operating systems that run on a hypervisor while containers are lightweight isolated processes that share the Host OS kernel. To achieve the scalability and flexibility required for modern cloud applications, each bare-metal server in the data center often houses multiple virtual machines, each of which runs multiple containers and multiple containerized applications that often share the same set of libraries and code, often referred to as images. However, while container frameworks are optimized for sharing images within a single VM, sharing images across multiple VMs, even if the VMs are within the same bare-metal server, is nearly non-existent due to the nature of VM isolation, leading to repetitive downloads, causing redundant added network traffic and latency. This work aims to resolve this problem by utilizing SmartNICs, which are specialized network hardware that provide hardware acceleration and offload capabilities for networking tasks, to optimize image retrieval and sharing between containers across multiple VMs on the same server. The method proposed in this work shows promise in cutting down container cold start time by up to 92%, reducing network traffic by 99.9%. Furthermore, the result is even more promising as the performance benefit is directly proportional to the number of VMs in a server that concurrently seek the same image, which guarantees increased efficiency as bare metal machine specifications improve.
Epigenetic factors and inflammaging: FOXO3A as a potential biomarker of sarcopenia and upregulation of DNMT3A and SIRT3 in older adults
Authors: Bogucka Diana , Wajda Anna , Stypińska Barbara , Radkowski Marcin Jerzy , Targowski Tomasz , Modzelewska Ewa , Kmiołek Tomasz , Ejma-Multański Adam , Filipowicz Gabriela , Kaliberda Yana , Dudek Ewa , Paradowska-Gorycka Agnieszka
Published: February 2025

Background

Epigenetic factors influence inflammaging and geriatric disorders such as sarcopenia and frailty. It is necessary to develop a biomarker/panel of biomarkers for fast and easy diagnostics. Currently, hard-to-access equipment is required to diagnose sarcopenia. The development of a biomarker/panel of biomarkers will prevent many older adults from being excluded from the diagnostic process.

Methods

In this study, we analyzed selected gene expression profiles, namely, SIRT1, SIRT3, SIRT6, DNMT3A, FOXO1, FOXO3A, and ELAVL1, in whole blood. The study included 168 subjects divided into five groups: patients hospitalized at the Geriatrics Clinic and Polyclinic with sarcopenia, frailty syndrome, or without those disorders (geriatric control), and non-hospitalized healthy controls (HC) aged 25 to 30 years and over 50 years.

Results

We revealed a lower mRNA level of FOXO3A (p<0.001) in sarcopenic patients compared to the geriatric controls. Furthermore, we detected upregulation of DNMT3A (p=0.003) and SIRT3 (p=0.015) in HC over 50 years old compared to HC aged 25 to 30 years. Interestingly, we observed 2 cluster formations during the gene expression correlation analysis (SIRT1, SIRT3, DNMT3A, and FOXO1, ELAVL1). We also noted correlations of clinical parameters with mRNA levels in the sarcopenic patients group, such as vitamin D level with SIRT1 (r=0.64, p=0.010), creatine kinase with SIRT3 (r=–0.58, p=0.032) and DNMT3A (r=–0.59, p=0.026), creatinine with DNMT3A (r=0.57, p=0.026), erythrocyte sedimentation rate (ESR) with FOXO3A (r=0.69, p=0.004), and lactate dehydrogenase (LDH) with FOXO3A (r=–0.86, p=0.007). In the frailty syndrome group, we noted a correlation of appendicular skeletal muscle mass (ASMM) with ELAVL1 (r=0.59, p=0.026) mRNA level. In the geriatric controls, we observed a correlation of serum iron with FOXO3A mRNA level (r=–0.79, p=0.036).

Conclusions

Our study revealed FOXO3A as a potential biomarker of sarcopenia. Furthermore, we observed a high expression of epigenetic factors (DNMT3A and SIRT3) in older adults.
Use of a universal targeting CAR T cell to simultaneously kill cancer cells and cancer-associated fibroblasts
Authors: Huang Bo , Zheng Suilan , Sudarshan Kasireddy , Mukkamala Ramesh , Srinivasarao Madduri , Sardesai Tushar , Yang Xiaofei , Chu Haiyan , Low Philip S.
Published: February 2025

CAR T cells therapies have demonstrated success in treating hematologic malignancies, but have proven less effective in eradicating solid tumors. While suppressive immune cells may contribute to reduced CAR T cell efficacies in malignant masses, cancer-associated fibroblasts (CAFs) are also believed to facilitate tumor survival by secreting growth factors, immunosuppressive cytokines, and extracellular matrix components that inhibit drug and immune cell filtration and facilitate metastasis. In an effort to eliminate both CAFs and cancer cells simultaneously, we have employed a universal CAR T cell that can attack both cell types when supplemented with appropriate bispecific adapters. We show here that tumor regression is indeed enhanced when CAR T cells are directed to concurrently kill both cancer cells and CAFs. We further demonstrate that simultaneous targeting of both cell types enhances CAR T cell proliferation, activation, tumor infiltration, and tumor distribution relative to targeting only a single cell type. Because all of these benefits are achieved in both cold and hot tumors without significant toxicity, we conclude that use of a universal CAR T cell in combination with multiple bispecific adapters can provide a safe, potent, cost-effective, and scalable alternative to the treatment of solid tumors with conventional CAR T cells.
Comprehensive analysis of immunogenic cell death-related genes in liver ischemia-reperfusion injury
Authors: Lu Kai , Li Hanqi , Sun Liankang , Dong Xuyuan , Fan Yangwei , Dong Danfeng , Wu Yinying , Shi Yu
Published: February 2025

Background

Liver ischemia-reperfusion injury (LIRI) is a critical condition after liver transplantation. Understanding the role of immunogenic cell death (ICD) may provide insights into its diagnosis and potential therapeutic targets.

Methods

Differentially expressed genes (DEGs) between LIRI and normal samples were identified, and pathway enrichment analyses were performed, followed by immune infiltration assessment through the CIBERSORT method. The consensus clustering analysis was conducted to separate LIRI clusters and single-sample Gene Set Enrichment Analysis (ssGSEA) was used to analyze the distinct immune states between clusters. Weighted Gene Co-Expression Network Analysis (WGCNA) was employed to identify hub genes associated with ICD. To establish diagnostic models, four machine learning techniques, including Random Forest (RF), XGBoost (XGB), Support Vector Machine (SVM), and Generalized Linear Models (GLM), were applied to filter gene sets. The receiver operating characteristic (ROC) curves were utilized to assess the performance of the models.

Results

Pathway enrichment results revealed significant involvement of cytokines and chemokines among DEGs of LIRI. Immune infiltration analysis indicated higher levels of specific immune functions in Cluster 2 compared to Cluster 1. WGCNA identified significant modules linked to LIRI with strong correlations between module membership and gene significance. The RF and SVM machine learning algorithms were finally chosen to construct the models. Both demonstrated high predictive accuracy for diagnosing LIRI not only in training cohort GSE151648 but also in validation cohorts GSE23649 and GSE15480.

Conclusions

The study highlights the pivotal roles of ICD-related genes in LIRI, providing diagnosis models with potential clinical applications for early detection and intervention strategies against LIRI.
Transmission error monitoring method of hydraulic excavating machinery based on M/T algorithm
Authors: Chen Fang
Published: February 2025

Introduction

Accurate speed measurement is crucial for improving the efficiency and reliability of the transmission system in hydraulic excavators. However, traditional M and T methods have their own limitations in speed measurement, especially in terms of measurement accuracy over a wide speed range.

Methods

A M/T velocity measurement algorithm combining the advantages of M and T methods was proposed to address this issue, and dynamic errors were obtained. The kinetic energy theorem can also be used.

Results

The experimental results show that under the normal load of unit tooth width F, the change rate of transmission error is less than 5% and less than 2% nM > 100N/mm.

Discussion

The monitoring method of hydraulic excavating mechanical transmission error has the advantages of high accuracy and strong adaptability, which can provide a new highway bureau for mechanical transmission error monitoring.
Identification of CMY-190, a novel chromosomally encoded AmpC β-lactamase, and plasmid-encoded KPC-2 in a clinical isolate of Citrobacter youngae
Authors: Liu Zeshi , Shen Siquan , Zhang Xue , Lei Jing , Tang Chengkang , Wu Shi , Lei Ke , Yin Jian , Zhang Yanping , Guo Yan , Geng Yan , Hu Fupin
Published: February 2025

This study investigates the antibiotic resistance phenotype and genotype of Citrobacter youngae strain YS01, isolated from a peritoneal effusion sample, focusing on both chromosomal and plasmid-mediated resistance mechanisms to inform clinical antibiotic therapy. Our results reveal the presence of the chromosomally encoded β-lactamase CMY-190 and the plasmid-encoded carbapenemase KPC-2, which confer resistance to cephalosporins and carbapenems, respectively. CMY-190 exhibits substrate and inhibition profiles similar to AmpC β-lactamases and shares 88.05% amino acid identity with the plasmid-encoded enzyme CFE-2 from Citrobacter freundii pJA99. DNA sequence analysis identified the ampR gene upstream of both blaCMY-190 and blaKPC-2. In addition, genes identified surrounding the ampR–ampC regions in C. youngae, including ORF1, the fumarate operon (frdABCD), blc, and lolB, a DNA fragment not present in other Citrobacter species. The ampR–ampC genes were cloned into the PHSG398 vector and expressed in Escherichia coli DH5α, with the transformed strain showing partial resistance to cephalosporins. The blaKPC-2 was carried by Tn1721, previously identified mainly in Asian strains of Klebsiella pneumoniae. The expression of KPC-2 was confirmed by the conjugation of the donor bacterium C. youngae with E. coli J53 and by the transformation of the plasmid containing blaKPC-2 into E. coli DH5α, with all the transformed strains demonstrating resistance to carbapenems and elevated carbapenem MICs. To the best of our knowledge, this is the first report of a novel chromosomally encoded AmpC β-lactamase gene, blaCMY-190, and the emergence of blaKPC-2 in C. youngae.
Rhizosphere microbiome metagenomics in PGPR-mediated alleviation of combined stress from polypropylene microplastics and Cd in hybrid Pennisetum
Authors: Zhao Si-Yu , Meng Yue-Liang , Yang Zi-Han , Li B. Larry , Li Yu-Ying , Han Hui , Liu Ling , Duan Peng-Fei , Chen Zhao-Jin
Published: February 2025

The simultaneous presence of microplastics (MPs) and heavy metals in soil may result in heightened toxicity, causing more significant adverse effects on plant growth. Plant growth-promoting rhizobacteria (PGPR) have demonstrated significant capacities in alleviating the toxic stress caused by the combined pollution of heavy metals and other contaminants. However, research on the impacts and processes of PGPR in alleviating stress induced by the combined pollution from MPs and heavy metals is still insufficient. This study involved a pot experiment to evaluate the ability of PGPR to mitigate stress induced by the combined pollution from polypropylene microplastic (PP MPs) particles of different sizes (6.5 μm and 830 μm) and the heavy metal cadmium (Cd) in the bioenergy plant hybrid Pennisetum. Moreover, metagenomic analysis was used to examine the effects of PGPR on the rhizospheric microbial community and function. The cocontamination of PP and Cd affected the growth of the hybrid Pennisetum differently depending on the size of the MPs particles, with the aboveground and underground lengths of the 6.5 μm PP + Cd experimental group being smaller than those of the 830 μm PP + Cd group. The PGPRs (Bacillus sp. Y-35, Bacillus sp. Y-62, Bacillus sp. Y-S, and Enterobacter sp. Y-V) successfully alleviated the stress caused by the combined pollution of PP and Cd, resulting in increases of 8.24 and 42.21% in the plant height and dry weight, respectively. The metagenomic studies indicated that the cocontamination of PP and Cd, along with PGPR inoculation, altered the composition of the rhizospheric bacterial community, leading to changes in microbial diversity indices and the composition of dominant groups such as Pseudomonadota, Actinomycetota, and Acidobacteriota. The functional analysis revealed that the main functional groups involved glucose metabolism, energy metabolism, signal transduction, and nucleotide metabolism. The MPs particle size and different PGPR significantly affected functions such as the pentose phosphate pathway, benzoate degradation, and amide biosynthesis. This study provides essential data and scientific evidence on the ecotoxicological effects of simultaneous contamination by MPs and heavy metals, as well as insights into potential bioremediation methods.