bluuebunny/crossref_metadata_2025 huggingface dataset:
Fixing Pitx3 gene Mutation with CRISPR-Cas9 Intervention in Zygotic Aphakia-Prone Mice – A Research Protocol
Authors: Sheikh Hussam , Alibhai Hassan , Thilliaimbalam Gowsith
Published: October 2021

Introduction: Despite the drawbacks of gene-editing, CRISPR-Cas9 remains a versatile tool for editing mutated genes. The mutated Pitx3 gene may cause aphakia in mice and Parkinsonism in humans. Pitx3 gene codes for the Pitx3 transcription factor involved in many tasks including the differentiation of dopaminergic neurons in the substantia nigra, tyrosine hydroxylase expression, dopamine transporter and lens development. We aim to edit mutated Pitx3 genes using CRISPR-Cas9 in embryonic-dopaminergic progenitor-neurons of mice and compare to wildtypes (WT) that do not undergo CRISPR-Cas9 intervention.
Methods: We will use 5 female mice, 2 homozygous for mice aphakia/Pitx3 mutation (Ak) and 3 standard pseudo-pregnant females. 2-male homozygous (+/+ Ak) mice with Ak will mate with the aphakic females (+/+ Ak). Dopamine levels in both (aphakic/non-aphakic) mice will be determined. We will extract embryonic stem cells (ESC) from aphakic female’s uterus and treat with CRISPR-Cas9 and homology-directed repair (HDR). Both treated and untreated ESC will be divided between 3 pseudo-pregnant females. Post-parturition, intervention success will be assessed using presence of optical lens, dopamine levels and restriction sequence expression in treated/untreated progeny.
Results: We expect to observe that untreated ESC zygotes (no CRISPR-Cas9 and HDR treatment) will not express normal Pitx3. This will result in low dopamine levels (inappropriate dopamine levels for their age group) and an aphakic mice progeny. Likewise, treated ESC zygotes will express normal Pitx3, hence have normal dopamine levels and non-aphakic phenotype.
Discussion: Progeny of both groups (treated/non-treated) will be examined for aphakia, dopamine levels and restriction sequence. Dopamine levels of treated mice will be compared to dopamine levels of WT mice. Should none of the treated progeny develop lenses or have normal dopamine levels, these mice will be sacrificed to target the restriction sequence in the inserted gene — helping to evaluate why the inserted gene is unexpressed.
Conclusion: This research examines CRISPR-Cas9 and HDR use on embryos with mutated genes that impair lens development and dopaminergic-neuron differentiation in humans and mice. It has potential of qualifying for clinical trials as the technique may be used to fix heritable disease-inducing genes that decrease longevity and quality of life in humans.
Primary Antiphospholipid Syndrome: A Hidden Predisposing Factor for Retinal Vein Occlusion and Choroidal Neovascular Membrane Formation Among Young Population
Authors: Abdulla Aldanasoury Romysaa , Almoosa Abdulla , Ayachi Seemantini , Al-Khalifa Saad
Published: October 2021

Background & Objectives: Antiphospholipid syndrome can lead to variable systemic and ophthalmic manifestations. The study aims to establish the relationship between retinal vein occlusion (RVO) or choroidal neovascular membrane (CNVM) with Antiphospholipid Syndrome (APS). Methods: A multicentric prospective cross-sectional study was carried out in three major eye centers in Bahrain that included The Eye Infirmary, Bahrain Royal Hospital, and King Hamad University Hospital. All young patients aging from 35 to 50 years, presenting with either RVO or CNVM and not known to have any underlying systemic disease were included in the study. Antiphospholipid confirmatory tests and coagulation profiles were done for all patients. Results: Total number of fourteen eyes of ten patients were enrolled in the study. Six patients had RVO, three out of them had central retinal vein occlusion (CRVO) and three had branch retinal vein occlusion (BRVO). Four patients had bilateral CNVM (total of 8 eyes). All patients recorded high activated partial thromboplastin time (aPTT) readings, six out of ten patients were labeled as primary APS, four of them had positive anti-cardiolipin antibodies and the other two patients were positive for plasma lupus anticoagulant. Conclusion: APS should be considered as an etiological factor in all cases of retinal vein occlusion and choroidal neovascular membrane affecting young otherwise healthy individuals. In this study, 60% of patients who fit the inclusion criteria were labeled as primary APS patients. Timely investigations and treatment in these cases can prevent major catastrophic thrombotic events which may involve any system or organ in the body. Keywords: Antiphospholipid syndrome, Blood coagulation tests, Eye, Lupus coagulation inhibitor, Retinal vein occlusion
Rhabdomyolysis After Implementing Whole-Body Electromyostimulation: A Case Study
Authors: Waleed Alaraifi Najla , Mohammed Mustafa Basem
Published: October 2021

Whole-body electromyostimulation is a new approach used to achieve weight loss and build muscles by activating different muscles groups through voluntary contractions generated by electrical impulses. This alternative approach is operated by a certified personal trainer, regulating the intensity of the electrical impulses to aid the muscular system to contract. Unaccustomed use of this technique leads to muscle destruction and a rise in creatine kinase level. A 25-year-old female began this therapy and experienced right flank tenderness associated with elevated serum creatine kinase (CK) levels. An impression of Rhabdomyolysis in the Emergency Department was given, followed by intravenous (IV) fluid administration. The patient consequently improved and was discharged with instructions. The study was projected to spread awareness regarding Whole-body electromyostimulation, which is tremendously promoted in Bahrain. This therapy may aid in client monitoring and improve the prognosis. Keywords: Adult; Electric stimulation therapy; Muscle; Musculoskeletal physiological phenomena; Rhabdomyolysis; Weight loss
Case Report of an Undisturbed Ectopic Pregnancy with Very High Human Chorionic Gonadotrophin (Î²-hCG)
Authors: Raza Gulmeen , Abdelwahab Ghorabah Maha
Published: October 2021

This is a case report of a patient with an undisturbed ectopic pregnancy and very high levels of human chorionic gonadotrophin (β-HCG). The patient presented to the emergency room at 9+1 weeks of gestation with mild abdominal pain and vaginal bleeding. She had an obstetric history of two previous cesarean section deliveries. On presentation, her human chorionic gonadotropin (β-HCG) was measured to be 26,530 mIU/ml, and after 18 hours, the β-HCG level was 25,660 mIU/ml. An ultrasound scan revealed no evidence of intrauterine pregnancy, a left ovarian cyst measuring 2.86 cm x 2.17 cm, and the presence of a mixed mass near the ovary measuring 3.92 cm x3.62 cm. The patient was diagnosed with a left tubal ectopic pregnancy and was taken for an immediate laparoscopy. Intraoperatively, the left tubal ectopic pregnancy was undisturbed and measured about 4-5 cm involving more than half of the fallopian tube. The mixed mass, along with the left fallopian tube, was removed as a whole. Keywords: Abdominal pain, Cesarean Section, Ectopic-pregnancy, Laparoscopy, Tubal pregnancy, Ultrasonography
Alport Syndrome: The Eye as a Window to the Human Body
Authors: Tareq Nusef Aysha , Almoosa Abdulla , Wagih Aly Wael
Published: October 2021

Alport syndrome (AS) is a rare genetic disease affecting type four collagen production, causing renal, auditory, and ophthalmic manifestations. This case report is about a 32-year-old male who was a known case of renal insufficiency and secondary hypertension and was referred to the ophthalmology department due to blurred vision. Based on the patient‘s history and ophthalmological findings, AS was diagnosed. Ophthalmic examination showed anterior lenticonus associated with sensorineural hearing loss (SNHL) and impaired renal function. This clinical case report sheds light on the role of ophthalmology in diagnosing AS. Keywords: Collagen, Crystalline lens, Hereditary nephritis, Ophthalmology, Renal insufficiency, Sensorineural hearing loss
ЦИФРОВИЗАЦИЯ СТРАХОВОГО РЫНКА РОССИИ: СОСТОЯНИЕ, ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ
Authors: Шобей Лариса Геннадьевна , Семченко Мария Петровна
Published: October 2021

В данной статье рассматривается развитие электронного страхования в России в целом и в разрезе отраслей на современном этапе. В ходе подготовки статьи был использован метод статистического анализа экономических показателей страхового рынка, исследования сайтов страховых компаний. Изучены основные направления цифровизации (интернетизация, индивидуализация и диджитализация), подразумевающие внедрение информационных технологий не только в работу с клиентами, но и во внутренние процессы деятельности страховщиков. В результате анализа процесса цифровизации российского страхового рынка были сделаны выводы о росте применения цифровых технологий российскими страховыми компаниями. Несмотря на то что цифровизация страховой отрасли в России пока находится на ранних стадиях, компании, внедряющие цифровые приложения и сервисы в свою деятельность, несомненно, будут иметь преимущества перед конкурентами, поскольку будут предлагать наиболее подходящий формат взаимодействия для удовлетворения постоянно меняющихся потребностей клиентов.
THE JOURNEY OF THE WRITER S. V. SAKHARNOV AND THE ARTIST N.A. USTINOV TO THE FAR EAST (ABOUT THE EXHIBITION “THE MULTICOLORED SEA OF NIKOLAI USTINOV”)
Authors:   The State Darwin Museum, TREGUB Nadezhda
Published: October 2021

The article discusses the animalistic exhibition “The Multicolored Sea of Nikolai Ustinov” in the Darwin Museum. The exhibition shows the interaction of the writer S.V. Sakharnov and the artist N.A. Ustinov in their joint journey to the Far East.
ASSESSMENT OF KNOWLEDGE, ATTITUDES AND PRACTICES OF CONSUMERS REGARDING FOOD SAFETY IN BAHRI LOCALITY, KHARTOUM STATE, SUDAN
Authors: Abdalkhalig. A Layla , M. H Mohammed Babiker , Ola I.E. , Abdalla Mohammed Abdelsalam
Published: October 2021

Food borne illnesses are prevalent in all parts of the world. Contaminated food Contributes to 1.5 billion cases of diarrhea in children each year, resulting in more than three million premature deaths (WHO).

     This study was conducted in August 2016 in Bahri locality, Khartoum state, to evaluate the knowledge, attitudes and practices of the consumers regard food safety.

     A total of questionnaire guided face to face interview with 120 respondents were carried out. Major food safety knowledge concepts include clean and hygiene, general sanitation, safe storage of food, proper cooking of food, use of thermometer in cooking. In general, the respondents had good knowledge about some food safety related issues and not enough knowledge about other issues.

      The results of the questionnaire showed that most of the respondents know the importance of washing hands before handling food 63% and wash the instruments and cleaning of the counter just after the preparation of the meal 83%. The results of the questionnaire revealed that 50% of the respondents know the importance of covering hands with a bandage and gloves when preparing food with cuts on their hands. Also, its reveal that 80% of the respondents didn`t know the proper way of thawing, and 84.2% of the respondents didn`t know food thermometer which use to ensuring proper cooking.

       This study recommend for Consumers should know and apply the five keys to safer food and implementing more training programs to the consumers to improve knowledge, attitudes and practices towards food safety.
A CONDIÇÃO DE VULNERABILIDADE SOCIAL DA MULHER NO BRASIL FRENTE À PANDEMIA DO COVID-19
Authors: MESQUITA IRLANDA BRANDÃO , Rodrigues Rachel de Mesquita
Published: October 2021

Os efeitos da pandemia do COVID-19 deram visibilidade às desigualdades de gênero que marcam historicamente a sociedade brasileira. A crise econômica tem evidenciado tanto a centralidade das ocupações
Como verificar a veracidade da Igreja nas CEBs?
Authors: Cipolini Pedro Carlos
Published: October 2021

A problemática a respeito da verdadeira Igreja é antiga: desde o Concílio de Nicéia (325), depois Constantinopla (381), a proposição do símbolo, confirmada em Éfeso (431) e Calcedônia (451), vem sendo ininterruptamente usada e confessada pela Igreja: “Cremos na Igreja una, santa, católica e apostólica”. A partir deste núcleo que remonta aos primeiros séculos da Igreja, podemos notar como também é antigo o interesse da Igreja em elaborar certos critérios que sirvam para demonstrar sua veracidade. Por mais transcendente que seja o sentido último da Igreja, ele deve oferecer critérios, algo visível e histórico, que permita demonstrar onde se encontra a verdade da Igreja, o que a torna verdadeira. Assim, a Igreja desenvolveu, através dos tempos, critérios de verificação de sua verdade, tanto pela própria necessidade de se auto-identificar (entre as outras igrejas), como pela necessidade de fazer-se crível...
Os católicos diante das eleições (1958-1986)
Authors: Silva Severino Vicente da
Published: October 2021

A Igreja se pensa e se compreende de formas diversas e a sua atuação no mundo é decorrente dessa forma de pensar e definir-se. Uma das maneiras de a Igreja se pensar é o modelo hierárquico e verticalista. Este modelo faz um corte radical entre o sagrado e o profano. A hierarquia se reserva o domínio do sagrado, o controle sobre os elementos simbólicos e, a partir daí, desenvolve um discurso e uma ação em que o profano é colocado em plano secundário, subalterno e dependente dos que formam a hierarquia, o clero...
As CEBs e os dilemas do processo de democratização
Authors: Oliveira Manfredo Araújo de
Published: October 2021

Em 1986, no encontro de Trindade, dois acontecimentos marcavam a atmosfera com um certo grau de otimismo: a euforia do “Plano Cruzado” e as eleições para o “Congresso constituinte”. Três anos depois, no VII Intereclesial de Caxias, as CEBs do Brasil tiveram a oportunidade de trocar experiências e reflexões a respeito da ação dos cristãos na sociedade dentro de um panorama político novo, que agora manifesta, com mais clareza, seu verdadeiro rosto...
Um encontro de ecumenismo, solidariedade e esperança: 7° Intereclesial das CEBs
Authors: Ribeiro Cláudio de Oliveira
Published: October 2021

Foram muitas as emoções... Muitos os momentos em que o coração bateu mais forte e a pele se tornou mais quente.... Muita coisa despertou a atenção...

Afinal éramos quase dois mil participantes, além dos 800 das equipes de serviço, não contando as mais de mil famílias que hospedaram com carinho os delegados do 7° Intereclesial das CEBs na Baixada Fluminense, RJ. Cada um com sua experiência, sua vivência, seu modo de agir e de pensar...
Transição republicana: Desafio e chance para a Igreja (I)
Authors: Piva Elói D.
Published: October 2021

Como o título já alude, individuamos o período de tempo cronologicamente situado entre a proclamação da República, aos 15 de novembro de 1889, e a promulgação da nova constituição, aos 24 de fevereiro de 1891. É neste lapso de tempo que a sociedade civil ensaia uma redefinição de seu modo de ser, que se re-situa na conjuntura histórica do tempo e que programa seu futuro. Por isso, qualificamos este período de “momento”, aludindo, em sua transitoriedade, às definições que possibilita. É, pois, neste lapso de tempo que nos circunscrevemos; é a novidade deste “momento” que buscamos...
Kehollinen toiminta opetuskeskustelun tukena valmistavassa opetuksessa
Authors: Helkiö Noora
Published: October 2021

This article examines bodily action as an interactional resource in instruction preparing for basic education. Using conversation analysis as method, the study seeks to answer two research questions: How does bodily action support and enable participation in the classroom interaction, and how do the teacher and the students use it in IRE/IRF-sequences? The first focus is on how the teacher uses bodily action when asking questions from the students. Secondly, the study focuses on how the teacher verbalizes students’ bodily action into verbal utterances. The writer argues that bodily action can enable participation in the classroom interaction as well as language teaching and language learning. For the teacher it serves as a pedagogical tool and for the student as a means of participation when learning a new language.
Venäjänkielinen alakoululainen suomen rakenteiden oppijana: omistuslauseen ja kieltolauseen kehittyminen oppimisen alkuvaiheessa
Authors: Yli-Piipari Marjo
Published: October 2021

This article examines, how two Russian-speaking children (ages 9 and 11) learn Finnish morpho-syntactic structures in interaction in a transitional classroom at primary school. It also discusses whether the influence of the mother tongue is observable in the learning process. The study focuses on the development of prototypical possessive structure and standard negation. The data consist of 15 lessons, video-recorded during one school year. The episodes, including the structures used by the children, are analysed by drawing on the principles of conversation analysis. The analyses show that for both children the possessive structure appears to be more complex to learn than the standard negation. However, the children’s acquisition of these structures follows different paths. At the end of the semester, the younger child’s possessive has not become established in Finnish, whereas the older child has begun to use it in accordance with the target language norms. The negation, however, follows the target language norms, in both children’s speech.
Opettajien käsitykset monikielisyydestä: heijastumia koulun kielipolitiikasta
Authors: Suuriniemi Salla-Maaria , Ahlholm Maria , Salonen Visajaani
Published: October 2021

This article examines teachers’ views (N = 2,864) on school multilingualism. The results have been analyzed using statistical methods and the conceptual frameworks of Spolsky’s language policy and Ruíz’s language orientations. The respondents were divided into three groups: positive (18%), deliberating (34%) and cautious (48%). The teachers’ language orientations were analyzed using three sum variables: teacher’s use of multiple languages, student’s use of multiple languages, and schools’ language attitudes. Classroom teachers were more positive about multilingualism than subject teachers and there were more teachers with cautious attitudes in schools where the number of foreign-language pupils was less than 5%. Additionally, the attitudes to multilingualism were more permissive in Swedish-speaking than in Finnish-speaking schools. Overall, the analysis of teachers’ views suggested that language policies vary. Finally, the individual respondents’ views did not fully correspond to any of Ruíz’s formulated language orientations.
Kohdekielisyyden normin oikeutus ja toteutus venäjänkielisessä CLIL-alkuopetuksessa
Authors: Kaunisto Maarit
Published: October 2021

This article examines the pedagogical-didactic legitimacy of an institutional language practice called the target language norm, and its implementation in Russian-language content-and-language-integrated (CLIL) classroom in primary education with 6–8-year-old students. Here, the language norm refers to an arrangement in which the teacher uses only the target language and restricts the students' use of their native tongue. The data consist of video recorded classroom interaction and ethnographic notes by the teacher-researcher, both collected during a two-year period. The microethnographic analysis shows that the students gradually adopt the norm as a part of their everyday school routine as they are socialized into classroom practices. The study argues that in certain contexts it is justified to introduce a language norm that supports the systematic and goal-oriented nature of language learning.
PENERAPAN ALAT BANTU LIFTER BRIDGE UNTUK MENGURANGI WAKTU DAN JARAK TEMPUH DALAM PEMINDAHAN BARANG SETENGAH JADI DI PT. TMMIN
Authors: Rahmawati Yulvani Anggi
Published: October 2021

PT TMMIN's logistics department is responsible for the smooth supply of component parts to the production line. In the delivery of parts, there is a problem, namely traffic disturbances in the PAD supply with the supply ip module. Both supplies cannot be in the same area due to insufficient area space. This situation causes the operator's workload to be a waste of steps and time. To overcome this problem, it is proposed to replace the part delivery tool that is currently used with a push dolly with a karakuri lifter bridge. Tool changes are carried out with 3M+1E aspects, namely method, material, man and environment. Change of equipment can affect factors such as no traffic disruptions with other supplies, reduction of SPS area, reduction of SPS distance to pp module and increasing company productivity efficiency.
ANTENA MIKROSTRIP RECTANGULAR DENGAN SLOT RECTANGULAR 2,45 DAN 5,85 GHZ MENGGUNAKAN TEKSTIL FLEECE UNTUK TELEMEDIS
Authors: Rachmaputri Fadilla Melania
Published: October 2021

Telemedicine is one of the technologies used for long-distance health services with wireless communication in the human body. This research is designing an antenna for telemedicine, namely a wearable antenna. The selection of textile materials used is a good choice for telemedicine because it has a relatively small size, can be bent, and comfortable to be used. This final project is designing a rectangular microstrip antenna with a dual-band rectangular slot in the ISM range of 2.45 and 5.85 GHz with a feed-line. The measurement results on the condition on the body for the frequency of 2.45 GHz are the gain value of 5.45 dB, VSWR of 1.4550, and the bandwidth of 180 MHz. For 5.85 GHz the gain value is 5.11 dB, VSWR is 1.5082, and the bandwidth is 260 MHz. The resulting radiation pattern is unidirectional.
PERANCANGAN DAN REALISASI ANTENA BOWTIE ANTIPODAL 1,6 GHZ UNTUK GROUND PENETRATING RADAR (GPR)
Authors: Anzani Dewi Septia , Wijanto Heroe , Arseno Dharu
Published: October 2021

Ground Penetrating Radar (GPR) merupakan teknologi yang memanfaatkan gelombang radio untuk mendeteksi lokasi, kedalaman, dan bentuk objek yang terkubur di bawah permukaan bumi. Salah satu komponen penting pada sistem GPR yaitu antena, yang terdiri atas antena transmitter dan receiver. GPR bekerja pada berbagai band frekuensi, salah satunya pada frekuensi 1,6 GHz. Untuk dapat mendeteksi objek, antena yang dibutuhkan harus memiliki spesifikasi bandwidth yang lebar, pola pancar unidirectional, dan ringing level yang rendah. Perancangan menggunakan antena jenis bowtie antipodal dengan penambahan metode edge cutting dan matching impedance sebagai antena pemancar yang bekerja pada frekuensi 1,6 GHz. Perancangan disimulasikan menggunakan software dan difabrikasi dengan menggunakan bahan substrat FR-4 Eproxy. Hasil rancangan menunjukkan bahwa antena yang telah difabrikasi dan diuji dapat memenuhi spesifikasi yang diinginkan yaitu bandwidth sebesar 540 MHz pada rentang 1,32 GHz – 1,86 GHz, returnloss -16,38 dB,  VSWR 1,35, gain 2,025 dBi dan pola radiasi bidirectional.
IMPLEMENTASI KEBIJAKAN PROTOKOL KESEHATAN SERTA DAMPAKNYA TERHADAP EKONOMI MIKRO DI KABUPATEN NGAJUK
Authors: Muzaqi Ajie Hanif , Layfani Muhammad Zainal
Published: October 2021

AbstrakKebijakan publik adalah cara dari pemerintah yang disepakati bersama untuk memenuhi tanggung jawab, seperti melindungi hak-hak dari masyarakat serta meningkatkan kesejahteraan warga Negara. Dunia pada sekarang ini sedang dilanda oleh wabah corona virus disease 2019 atau sering disebut Covid-19. Membuat berbagai sektor menjadi berantakan, tak terkecuali sektor ekonomi. Pemerintah Provinsi Jawa Timur kemudian membuat kebijakan Peraturan Gubernur Nomor 53 Tahun 2020 Tentang Penerapan Protokol Kesehatan dan Pengendalian Covid-19 untuk meminimalisisr peyebaran virus corona. Dimana peraturan tersebut wajib dipatuhi oleh seluruh masyarakat Jawa Timur. Adapun jenis penelitian ini adalah kualitatif  yaitu metode yang berusaha menafsirkan dan memahami makna suatu peristiwa interaksi tingkah laku manusia dalam situasi tertentu menurut perspektif peneliti sendiri. Hasil penelitian menyebutkan bahwa kebijakan publik yang dikeluarkan Pemerintah Provinsi Jawa Timur melalui Peraturan Gubernur Nomor 53 Tahun 2020 banyak merugikan pelaku UMKM, karena penghasilan mereka menjadi berkurang akibat dari pembatasan jam operasional dan pembatasan pengunjung atau tidak diperbolehkan adanya kerumunan. Kata Kunci: Kebijakan Publik; Covid-19; Peraturan Gubernur. Abstract  Public policy is a mutually agreed way of government to fulfill responsibilities, such as protecting the rights of the community and improving the welfare of citizens. The world is currently being hit by an outbreak of the corona virus disease 2019 or often called Covid-19. Making various sectors into a mess, including the economic sector. The East Java Provincial Government then made a policy on Governor Regulation Number 53 of 2020 concerning the Implementation of the Health Protocol and Covid-19 Control to minimize the spread of the corona virus. Where these regulations must be obeyed by all the people of East Java. The type of this research is qualitative, namely a method that seeks to interpret and understand the meaning of an event of human behavior interaction in certain situations according to the researcher's own perspective. The results of the study stated that the public policies issued by the East Java Provincial Government through Governor Regulation Number 53 of 2020 caused a lot of harm to MSME actors, because their income was reduced due to restrictions on operating hours and visitor restrictions or no crowds were allowed. Keywords: Public policy; Covid-19; Governor Regulation.
PELAYANAN PUBLIK DI BADAN PENANGGULANGAN BENCANA DAERAH KOTA KEDIRI: STRATEGI POSKO SIAGA PENANGANAN PENYEBARAN COVID-19
Authors: Prissando Fendy Artha
Published: October 2021

AbstrakPelayanan publik merupakan salah satu perwujudan dari fungsi pada aparatur negara sebagai abdi masyarakat. Pelayanan publik yang professional itu artinya pelayanan publik yang bercirikan oleh adanya akuntabilitas dan responsibilitas dari pemberi layanan. Pelayanan publik pada dasarnya merupakan sebuah upaya individu, kelompok atau birokrasi untuk memberikan bantuan serta kemudahan kepada masyarakat untuk mencapai suatu tujuan tertentu. Tugas terpenting dari pelayanan publik ini adalah memberikan pelayanan terbaik kepada masyarakat. Pelayanan publik memiliki suatu tujuan untuk memenuhi kebutuhan masyarakat. Penelitian ini ditujukan untuk mengetahui bagaimana Pelayanan Publik di Badan Penanggulangan Bencana Daerah (BPBD) Kota Kediri serta mengetahui strategi posko siaga penanganan penyebaran Covid-19. Metode penelitian yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif dan teknik pengumpulan data melalui observasi, wawancara secara mendalam kepada informan, dan dokumentasi. Hasil penelitian menujukkan bahwa kualitas pelayanan publik di Kantor Badan Penanggulangan Bencana Daerah (BPBD) Kota Kediri sudah baik dan sudah memberikan pelayanan publik dengan tepat kepada masyarakat yang membutuhkan bantuan dengan posko siaga.Kata Kunci: Kualitas; Pelayanan Publik; Prinsip Pelayanan. AbstractPublic service is one manifestation of the function of the state apparatus as a public servant. Professional public service means public service characterized by accountability and responsibility from service providers. Public service is basically an individual, group or bureaucratic effort to provide assistance and convenience to the community to achieve a certain goal. The most important task of this public service is to provide the best service to the community. Public services have a purpose to meet the needs of the community. This study was aimed to find out how the Public Service in the Regional Disaster Management Agency (BPBD) of Kediri City and to find out the strategy of the standby post for handling the spread of Covid-19. The research method used in this study is a qualitative descriptive method and data collection techniques through observation, in-depth interviews with informants, and documentation. The results of the study show that the quality of public services at the Office of the Regional Disaster Management Agency (BPBD) of Kediri City is good and has provided appropriate public services to people who need assistance with standby posts.Keywords: Quality; Public service; Service Principles.
Godina i nešto primjene Zakona o parničnom postupku
Authors: Tironi Ivan , Bodul Dejan
Published: October 2021

Zakon o izmjenama i dopunama Zakona o parničnom postupku stupio je na snagu 1. rujna 2019. Ratio ovoga ambicioznog poduhvata potreba je izmjene niza instituta, odnosno neophodnost uvažavanja prijedloga sudske prakse koja su rezultat dugogodišnjih iskustava. Radi ostvarivanja ovih ciljeva, Novelom su u području funkcionalnoga postupovnog prava preoblikovani mnogi procesni instituti te je postavljen znatan broj novih pravila. Mišljenje je autora kako je (i sada) procesna regulativa normativno zadovoljavajuća u pogledu pravne usustavljenosti, pravne tehnike i dosljednosti u normiranju. Tomu su svakako i pridonijeli i sudovi kroz sudsku praksu i svoja postupanja te intenzivno i stalno razrađivanje zakonskih rješenja. Ipak, uvažavajući činjenicu kako je problematika građanskog postupka i u zemljama s dugom pravnom tradicijom dinamično područje u kojem se neprestano traže nova rješenja koja će pratiti trend promjena, pitanje svrsishodnosti i potrebe implementacije izmjena i dopuna predmetne legislative, u kontekstu osuvremenjivanja de lege lata rješenja, iznimno je aktualno. Stoga je cilj rada analizirati razdoblje koje je prošlo od uvođenja izmjena postupovnoga prava. Želja je autora utvrditi je li se usavršio i poboljšao nacionalni režim građanskoga postupka, dakle proceduralni mehanizam za olakšavanje učinkovitijeg rada na predmetima te je li potrebno promišljati i o daljnjim izmjenama. Složenost predmeta istraživanja i postavljeni zadatci uvjetovali su izbor metoda pa je u istraživanju ponajprije primijenjen normativnopravni i iskustveni/praktični metodološki pristup. Autori smatraju bitnim istaknuti kako s obzirom na to da opseg rada ne dopušta detaljnu raščlambu ove problematike, prinuđeni su ograničiti se isključivo, na
neke aspekte zadnje novele.
Müstakil Mekkî-Medenî Eserleri ve Müellifleri Üzerine Bir Literatür İncelemesi
Authors: FİDAN Ayşenur
Published: October 2021

Bir ilim olarak Mekkî-Medenî; Esbâb-ı nüzûl, Nâsih-Mensûh, Ahkâmu’l-Kur’ân, Fedâilu’l-Kur’ân ve Hasâisu’l-Kur’ân gibi Kur’ân ilimlerinin pek çok dalıyla yakından irtibatlıdır. Mekkî-Medenî’nin ortaya çıkıp şekillenmesinde de diğer ilimlerle irtibatlı bu arka plan oldukça etkili olmuştur. Özellikle Ahkâm ve Nâsih-Mensûh’un, Mekkî-Medenî’ye büyük oranda zemin teşkil ettiği görülmektedir. Çünkü tarihi süreçte Mekkî-Medenî, âyetlerin önceliği-sonralığı dolayısıyla nâsih mi mensûh mu olduğunu belirleyen bir kriter işlevi görmüştür. Tam da bu sebeple konu; Ahkâmu’l-Kur’ânlarda, Fıkıh Usûlü, Nâsih-Mensûh ve Ulûmu’l-Kur’ân eserlerinde çokça yer bulmuş fakat konunun müstakil olarak ele alındığı eserlerin sayısı az olmuştur. Ansiklopedik Ulûmu’l-Kur’ân eserlerinin aktarımına göre Mekkî b. Ebî Tâlib (ö. 437/1045) ve İzzüddin ed-Dîrînî (ö. 694/1295) konuyla ilgili müstakil eser ortaya koyan iki isimdir. Fakat olabildi-ğince geniş çaplı taramaya gayret gösterdiğimiz biyografik kaynaklarda bu isimlerin konuyla ilgili eser ortaya koyduğu bilgisi yer almamaktadır. Diğer yandan her iki müellifin de telifâtının çokluğuyla ve Ulûmu’l-Kur’ân’daki uzmanlıklarıyla şöhret bulan kişiler olduğu aktarılmaktadır. Nitekim biyografik kaynaklar da müelliflerin, sayıları çok olan bu eserlerinin tümünü zikrettikleri iddiasında değildir. Bu durum da Ulûmu’l-Kur’ân kaynaklarının Mekkî-Medenî başlığında bu iki isimden yapılan nakillerin kaynak eserini bulma çabasını doğurmuştur. Bu çalışma, ansiklopedik Kur’ân ilimleri kaynaklarının zikrettiği iki isim dışında başka isim ve eserlerin var olup olmadığını, varsa bunların bilinirliğinin ne oranda olduğunu araştırmayı hedeflemiştir. Bu minvalde hem zikri geçen iki isme hem de biyografik kaynaklarda konuyla ilgili eser ortaya koyduğu bilgisine ulaştığımız diğer isimlere yer verilmiş, özellikle bu iki isim üzerinden kaynakların verdiği bilgiler teyid edilmeye çalışılmış ve konuyla ilgili müstakil çalışmaların az oluşu üzerine değerlendirmelerde bulunulmuştur.
İdrîs-i Bitlisî’nin Envârü’t-Tenzîl Hâşiyesindeki Tahkik Tavrı
Authors: BÜYÜK Enes
Published: October 2021

Tefsir tarihinde 7. asırdan sonra yoğun bir şekilde görülen şerh-hâşiyeler, tefsir edebiyatının önemli bir halkasını oluşturmuştur. Üzerine hâşiyelerin yazıldığı en önemli iki tefsir metni Zemahşerî’nin el-Keşşâf’ı ve onu merkeze alan Beyzâvî’nin Envârü’t-tenzîl’idir. Hâşiyeler musanniflerin ifadelerini veya bu ifadeler bağlamında çeşitli meseleleri ele alarak âyetlerin tefsir sürecine önemli katkılar sunmuştur. Bu itibarla Envârü’t-tenzîl hâşiyeleri içerisinde hem aklî ve naklî ilimlerde mahir hem de önemli bir tarihçi ve siyasetçi olan İdrîs-i Bitlîsî’nin hâşiyesi dikkat çekici bir niteliğe sahiptir. Bu makalenin inceleme konusunu oluşturan hâşiyede, Bitlîsî’nin temelde nasıl bir tavır sergilediği önemlidir. Zira hâşiyelerde şârihler asıl metni sadece şerh edici, mevcut görüşleri ihtisar edici, nakledici veya tahkik edici bir tavır sergileyebilmektedirler. Mezkûr tavırların herbiri belli bir maksada dayalı veya faydaya dönük olmakla birlikte özellikle tahkik tavrının sergilendiği hâşiyeler asıl metinlerdeki ve bunlar üzerine yazılan hâşiyelerdeki tespitleri, görüş ve iddiaları bazen mukayese ve muhakeme bazen de tahlil, tenkit, tahkim, tercih, tasdik veya tafsil gibi açılardan inceleyerek mevcut birikime ve neticede âyetlerin tefsirine katkı sağlayıcı bir niteliğe sahip olmuştur. Bu sebeple makalede Bitlîsî’nin hâşiyede nasıl bir tavır sergilediği deskriptif yöntem ve mukayeseli metin okuma yöntemiyle tespit edilmiş, hangi özelliğe sahip hâşiyelerden olduğu ortaya konulmaya çalışılmıştır. Bunun öncesinde de hâşiyenin müellife aidiyeti, teknik özellikleri ve kaynakları hakkında bilgi verilmiştir.
Bahaya kekurangan mium air putih bagi kesehatan
Authors: Q.A Zulfa Firda
Published: October 2021

Saat tubuh kurang minum air putih atau cairan lain, seseorang bisa mengalami dehidrasi. Dehidrasi dapat membuat volume plasma darah yang mengandung protein menurun. Dampaknya, tekanan darah orang yang kurang minum air putih juga bisa ikut turun. Mual dan muntah.
Review Jurnal dengan Keterkaitan Ekologi Pangan dan Gizi
Authors: Febrianti Andi Ulfa
Published: October 2021

Hubungan sosial budaya dengan kejadian stunting pada balita usia 24-59 bulan di desa Bone-bone kecamatan Baraka kabupaten Enrekang tahun 2020
Augmenting Human Cognition with a Digital Submarine Periscope Human-Machine Interface
Authors: Michailovs Stephanie , Irons Jessica , Howard Zachary L , Pond Stephen , Schmitt Megan , Stoker Matthew , Visser Troy A. W. , Bell Jason , Pinniger Gavin , Fitzgerald Madison , Huf Samuel , Carter Owen , Loft Shayne
Published: October 2021

Advances in opto-electronics enables replacement of traditional periscopes which display only a portion of the horizon, with digital periscopes, which can potentially display a full 360° panoramic digital representation of the horizon. One advantage of an increased field of view (FOV) might be to reduce memory requirements and improve integration of visual information over time, thereby improving detection of vessels (contacts) at sea. Another potential advantage of moving to digital periscopes is that imagery can be paired with digital aids that can replace or simplify tasks traditionally performed manually, such as contact identification. This study compared a low-FOV visual concept to a high-FOV concept (Experiment 1), and then traditional analysis tools with digitized analysis tools (Experiment 2). The high-FOV concept and digitized tools provided a range of perceived workload, perceived usability, and performance benefits to the human operator, and we conclude that digitally augmenting the periscope can potentially support submariner tasks. THIS VERSION (18 Jul 23) AND ALL PREVIOUS VERSIONS HAVE NOT BEEN PEER REVIEWED. PLEASE DO NOT CITE WITHOUT THE AUTHOR'S PERMISSION.
Kesehatan Masyarakat
Authors: Faizin Rahman
Published: October 2021

Merokok adalah suatu aktifitas yang tidak asing lagi dalam kehidupan sehari-hari. Kegiatan ini sudah menjadi kebiasaan bagi sebagian kaum pria bahkan tak jarang beberapa wanita pun juga ada yang mengkonsumsinya. Rokok sudah menjadi konsumsi wajib yang tidak dapat ditinggalkan. Konsumsi rokok didominasi dari kalangan remaja,orang tua bahkan sudah mulai dikonsumsi oleh anak sd dan smp yang masih dikategorikan dibawah umur. Semua kalangan bias mengkonsumsi rokok entah kalangan ekonomi atas, menengah terlebih kalangan bawah,tak hanya itu kaum intelek,pendidik serta tokoh-tokoh agama pun tak mau kalah.Mengkonsumsi rokok menghasilkan asap yang sangat berbahaya bagi kesehatan. Si perokok sendiri adalah sebagai Perokok Aktif. Sementara orang yang berada disekitarnya yang ikut menghirup asapnya adalah sebagai Perokok Pasif. Perokok pasif lebih cenderung berbahaya bila disbanding dengan perokok aktif karena perokok pasif menghisap 75%bahan berbaya ditambah lagi separuh dari asap yang dihembuskan. Sebatang rokok mengandung 4000 bahan kimi beracun yang sangat berbahaya dan tidak kurang 69 diantaranya bersifat karsinogenik ( zat yang dapat menyebabkan pertumbuhan sel kanker). Sehingga udara yang tercemar asap rokok sangat membahayakan kesehatan. Seperti yang sering kita lihat peringatan pada bungkus rokok bahwasanya benar adanya bahwa kandungan dari bahan kimia pada asap rokok dapat menyebabkan berbagai penyakit seperti serangan jantung, gangguan pembuluh darah,stroke, kanker paru-paru, kanker mulut,juga dapat menurunkan kesuburan, pertumbuhan janin baik dari segi fisik maupun IQ (Intelegen Quotient) yang melambatkan gangguan imunitas bayi bahkan mampu mengakibatkan peningkatan kematian/keguguran pada janin.
Kesehatan masyarakat
Authors: ALDIANTO MUHAMMAD AFFAN
Published: October 2021

1. Latar Belakang Masa remaja merupakan masa dimana seorang individu mengalami peralihan dari satu tahap ke tahap berikutnya dan mengalami perubahan baik emosi,tubuh,mint pola perilaku, dan juga penuh dengan masalah masalah. Oleh karenanya, remaja sangat rentan sekali mengalami psikososial, yakni masalah psikis atau kejiwaan yang timbul akibat terjadinya perubahan sosial. Sebenarnya seorang pelajar belum boleh merokok di kalangan sekolah, masyarakat atau kalangan yang lainya. Karena hal ini dapat berdampak buruk bagi kesehatannya. Biasanya ini dilakukan oleh para remaja karena kondisi emosi mereka yang tidak stabil membuat mereka melakukan segala hal. Hal ini di sebababkan kurangnya penyuluhan tentang bahay merokok di kalangan sekolahatau masyarakat.Merokok merupakan salah satu masalah yang sulit di pecahkan. Apalagi sudah menjadi masalah nasional, dan bahkan internasional. Hal ininmenjadi sulit, karena berkaitan dengan banyak faktor yang saling memicu, sehingga seolah-olah sudah menjadi lingkaran setan. Di tinjau dari segi kesehatan, merokok harus di hentikan karena menyebabkan kanker di penyumbatan pembuluh darah yang mengakibatkan kematia, oleh karena itu merokok harus di hentikan sebagai usaha pencegahan sedini mungkin. Terlebih diketahui bahwa sebagian besar adalah remaja sehingga perluadanya pencegahan dini yang dimulai dari pihak sekolah dan orang tua. Para perokok merasakan nikmatnya merokok begitu nyata, sampai dirasa memberikan rasa menyenangkan dan menyegarkan sehingga setiap harinya harus menyisihkan uang untuk merokok. Kelompok lain, khususnya remaja pria, mereka menganggap merokok adalah merupakan ciri kejantanan yang membanggakan, sehingga mereka yang tidak merokok malah justru diejek. Padahal mereka sadar bahwa merokok dapat membahayakan kesehatan bahkan menimbulkan banyak penyakit serius. Banyak terdapat kandungankandungan yang berbahaya di dalam rokok sehingga menimbulkan dampak buruk bagi Kesehatan
Penghimbauan Protokol Kesehatan Saat Pandemi
Authors: Angelina Indah Aprilia
Published: October 2021

Artikel ini bertujuan untuk menjawab bagaimana upaya pemerintah dalam mewujudkan pemenuhan vaksinasi Covid-19 sebagai hak atas kesehatan bagi masyarakat adat di masa pandemi. Pemberian vaksinasi Covid-19 kepada setiap warga negara kini telah menjadi upaya dalam menyelesaikan pandemi Covid-19. Salah satu kelompok yang rentan pada pandemi Covid-19 ini adalah masyarakat adat yang sebelumnya telah rentan karena keterbatasan akses kesehatan. Artikel ini merupakan penelitian hukum normatif dengan menggunakan pendekatan perundang-undangan. Hasilnya adalah pemerintah telah memasukan masyarakat adat ke dalam prioritas vaksinasi dalam Peraturan Menteri Kesehatan Nomor 84 Tahun 2020.
Pengaruh peran orang tua terhadap motivasi belajar pada pembelajaran berbasis online siswa SD Negeri Pannara Kota Makassar
Authors: rianti
Published: October 2021

Catatan terkait dengan peran orang tua terhadap motivasi belajar pada pembelajaran berbasis online siswa SD negeri Pannara kota makassar
Hak dan kewajiban Remaja Dalam Kesehatan Psikologi
Authors: ayu Salva
Published: October 2021

Dunia remaja adalah dunia yang penuh warna dan unik. Dari sekian untaian pertumbuhan dan perkembangan remaja, masa yang paling sering menjadi perhatian tentu saja adalah ketika masa pubertas itu datang. Jenjang pertumbuhan secara jasmani tersebut dapat dipakai sebagai ciri pertumbuhan remaja di tingkat awal yang selanjutnya akan dilanjutkan dengan masa ketika remaja mengalami fase penyesuaian diri antar-pribadi dan lingkungan sosial yang lebih luas. Sejak itulah muncul berbagai kelompok remaja yang disebut dalam berbagai istilah. Di dalam artikel ini, terdapat uraian seputar perkembangan psikologi remaja, peranan orang tua terhadap psikologi anak, dan pengaruh lingkungan terhadap perkembangan psikologi anak, serta kewajiban remaja dalam kesehatan psikologinya. Kesimpulannya anak dan remaja adalah generasi penerus, mereka menjadi bakal atau calon yang penting. yang akan menggantikan tugas-tugas para seniornya, yakni meneruskan membangun bangsa dan negara. Tanpa mereka maka negara bukan apa-apa, maka setidaknya kita bisa memahami psikologi, sikap dan kemauan-kemauan mereka sehingga akan tercipta hubungan yang harmonis yang bisa menjadikan remaja menjadi generasi yang aktif dan produktif.
When open data closes the door: A critical examination of the past, present and the potential future for open data guidelines in journals
Authors: Prosser Annayah Miranda Beatrice , Hamshaw Richard , Meyer Johanna , Bagnall Ralph , Blackwood Leda , Huysamen Monique , Jordan Abbie , Vasileiou Konstantina , Walter Zoe
Published: October 2021

Opening data promises to improve research rigour and democratise knowledge production. But it also poses practical, theoretical, and ethical risks for qualitative researchers in particular. Discussion about open data in qualitative social psychology predates the replication crisis. However, the nuances of this ongoing discussion have not been translated into current journal guidelines on open data. In this paper, we summarise ongoing debates about open data from qualitative perspectives, and through a content analysis of 261 journals, we establish the state of current journal policies for open data in the domain of social psychology. We critically discuss how current common expectations for open data may not be adequate for establishing qualitative rigour, can introduce ethical challenges, and may place those who wish to use qualitative approaches at a disadvantage in peer review and publication processes. We advise that future open data guidelines should aim to reflect the nuance of arguments surrounding data sharing in qualitative research, and move away from a universal ‘one-size-fits-all’ approach to data sharing. Overall, this paper summarises the past, present of open data guidelines in social psychological journals, and offers some recommendations on how to move towards a more inclusive future for open data in qualitative methods.
Perceiving the weird and the wonderful. The mysterious metaphysics of phenomenology, art and science.
Authors: Rose David
Published: October 2021

What is it that appears to us: an objective reality or a subjective illusion? A brief history of the continental philosophical approach to this question is given, followed by an introduction to the recent continental movement toward Realism, which accepts there must be mind-independent entities of some kind. Yet if such an objective reality exists this raises the problem of how we can possibly conceptualise what exists and happens there, since by definition it is beyond our concepts — or at least beyond our current ones. Hence it seems mysterious, weird and wonderful. I illustrate how the arts and sciences have independently approached this question, and suggest some commonalities in their conclusions. Finally, I discuss the importance of individual differences in how we perceive and think.
Parts and Wholes in Scene Processing
Authors: Kaiser Daniel , Cichy Radoslaw M.
Published: October 2021

During natural vision, our brains are constantly exposed to complex, but regularly structured environments. Real-world scenes are defined by typical part-whole relationships, where the meaning of the whole scene emerges from configurations of localized information present in individual parts of the scene. Such typical part-whole relationships suggest that information from individual scene parts is not processed independently, but that there are mutual influences between the parts and the whole during scene analysis. Here, we review recent research that used a straightforward, but effective approach to study such mutual influences: by dissecting scenes into multiple arbitrary pieces, these studies provide new insights into how the processing of whole scenes is shaped by their consistent parts and, conversely, how the processing of individual parts is determined by their role within the whole scene. We highlight three facets of this research: First, we discuss studies demonstrating that the spatial configuration of multiple scene parts has a profound impact on the neural processing of the whole scene. Second, we review work showing that cortical responses to individual scene parts are shaped by the context in which these parts typically appear within the environment. Third, we discuss studies demonstrating that missing scene parts are interpolated from the surrounding scene context. Bridging these findings, we argue that efficient scene processing relies on an active use of the scene’s part-whole structure, where the visual brain matches scene inputs with internal models of what the world should look like.
Visual Art Therapy dalam Bimbingan dan Konseling
Authors: Rahmat Febri
Published: October 2021

Absrak: Visual art in counseling merupakan salah satu Teknik konseling seni yang difokuskan pada visualisasi atau simbolisasi untuk mengungkapkan permasalahan konseli melalui berbagai cara seperti mewarnai, menggambar, dan mematung. Teknik ini digunakan untuk membantu konseli dalam mengungkapkan hal – hal yang terkadang sulit terungkap secara verbal, pengalaman – pengalaman atau harapan yang terepresi di alaam bawah sadar, dan symbol – symbol subyektif yang ia miliki.Dengan menggunakan Teknik visual art ini konseli mampu mengungkapkan perasaan yang sulit untuk di ungkapkan melalui kata – kata bisa diganti dengan menggambarkan apa yang ada atau apa yang sedang dia pikirkan ketika diminta untuk membuat sebuah gambar yang sedang menggambarkan perasaannya saat ini dengan begitu konselor pun tau perasaan menggangu yang sedang dirasakan oleh konseli.
The metaphysics of perception: enactivism, phenomenology and information.
Authors: Rose David
Published: October 2021

Enactivism is a major research programme in the philosophy of perception. Yet its metaphysical status is unclear, since it is claimed to avoid both idealism and realism yet still has aspects of both within it. One attempt to solve this conundrum is based on the fusion of enactivism with phenomenology and the mathematical concept of symmetry breaking (Moss Brender, 2013). I suggest this is not entirely successful and propose it needs the addition of a multi-level, non-reductive metaphysics (for example, Informational Structural Realism). The processes we commonly call ‘perception’ are causal transfers of information at certain levels in the hierarchy of meaningful structures that comprise physical reality. Phenomenologists could use the word ‘perception’ metaphorically across all levels, although realists need not do so.