bluuebunny/crossref_metadata_2025 huggingface dataset:
Spirocerca lupi infection in the dog: aberrant migration
Authors: Harrus S , Harmelin A , Markovics A , Bark H
Published: September 2014

The nematode Spirocerca lupi (S. lupi), a parasite of dogs and other carnivores, affects mainly the esophagus and the aorta leading to gastrointestinal, respiratory, and circulatory signs. Aberrant migration of the worm to unusual anatomical structures, especially the thoracic cavity, resulting in atypical clinical signs is being reported more frequently. Aberrant migration of S. lupi is reviewed, and two such cases (i.e., migration to the heart, causing an aortico-pulmonary "window-like" opening, and to a subcutaneous abscess in the caudal thoracic region) are presented.
Canine mucosal leishmaniasis
Authors: Font A , Roura X , Fondevila D , Closa JM , Mascort J , Ferrer L
Published: September 2014

Four dogs infected with Leishmania had proliferative lesions on the mucosae of the penis, tongue, oral cavity, prepuce, or nose. These mucosal, nodular lesions produced by parasites of the genus Leishmania have not been described previously in the dog. Leishmaniasis should be considered in the differential diagnosis of tumor-like lesions of mucous membranes.
Aggressive, undifferentiated sarcoma with widespread metastasis in a six-month-old Neopolitan mastiff
Authors: Sanders NA , Kerlin RL , Dambach DM
Published: September 2014

A six-month-old Neopolitan mastiff presented for a rapidly growing cervical mass. Undifferentiated sarcoma was diagnosed at post mortem based on histopathology and immunohistochemistry. Metastases to mediastinum, pleura, lungs, liver, kidneys, omentum, mesentery, and multiple lymph nodes were present. Soft-tissue sarcomas are reported infrequently in children and young dogs. The cell of origin often is difficult to determine due to poor differentiation and rapid growth of these neoplasms.
Feline leprosy: spontaneous remission in a cat
Authors: Roccabianca P , Caniatti M , Scanziani E , Penati V
Published: September 2014

A two-year-old, male domestic shorthair with a solitary lesion of the right forelimb was presented for fine-needle aspiration biopsy of a suspected cutaneous, neoplastic process. Neutrophils, lymphocytes, and acid-fast bacilli packed in the cytoplasm of foamy macrophages and giant cells were seen on cytological examination. Bacteriological culture of the material from the skin lesion was negative for Mycobacterium spp. Intraperitoneal injection of homogenized material from the lesion resulted in generalized mycobacteriosis in one mouse after 10 months. Based on these results, a diagnosis of feline leprosy was made. No medical or surgical therapy was performed. Nonetheless, the lesion showed progressive and complete spontaneous remission within 3.5 months from the time of diagnosis; after 14 months, the cat still is free of disease.
Ophthalmic manifestations and complications of dental disease in dogs and cats
Authors: Ramsey DT , Marretta SM , Hamor RE , PAJr Gerding , Knight B , Johnson JM , LH2nd Bagley
Published: September 2014

Ophthalmic manifestations of dental disease may occur in dogs and cats because of the proximity between posterior maxillary teeth and the orbit. Ophthalmic disorders may be diagnosed promptly, but the initiating dental disease may be overlooked. Inappropriate diagnosis and treatment of dental disease may result in loss of teeth, irreversible vision-threatening ophthalmic disease, or, ultimately, loss of the globe. When ophthalmic examination results are suggestive of a primary dental disorder, thorough examination of the maxillary teeth is imperative to diagnose appropriately the underlying dental disease. Therapy should include treatment of the dental disease and secondary ophthalmic disorders.
Evaluation of fibular head transposition, lateral fabellar suture, and conservative treatment of cranial cruciate ligament rupture in large dogs: a retrospective study
Authors: Chauvet AE , Johnson AL , Pijanowski GJ , Homco L , Smith RD
Published: September 2014

Sixty-one large dogs (weighing 22.7 kg or more) with cranial cruciate ligament ruptures (CCLRs) were treated with either fibular head transpositions (FHTs; n = 22 stifles), lateral fabellar sutures (LFSs; n = 39 stifles), or conservatively (CT; n = 11 stifles) with rest and aspirin. Based on owner evaluation, dogs treated with FHTs or CT did not perform as well as dogs treated with LFSs (p less than 0.05). There was no difference in owner evaluation scores for the dogs treated with FHTs or CT. Thirty dogs were reevaluated by investigators. No differences between treatment groups regarding age, sex, or time until diagnosis were noted. No differences in scores for lameness, stifle instability, or forceplate analysis among the treatment groups were observed. Degenerative joint disease progressed or remained severe regardless of treatment, based upon radiographic evidence.
Gastric dilatation-volvulus in the dog with histological evidence of preexisting inflammatory bowel disease: a retrospective study of 23 cases
Authors: Braun L , Lester S , Kuzma AB , Hosie SC
Published: September 2014

The gastric dilatation-volvulus (GDV) syndrome in the dog is considered to be multifactorial. The medical records of 42 dogs treated for GDV between 1990 and 1994 were reviewed in an effort to evaluate the correlation between GDV and preexisting gastrointestinal disease. Twenty-three cases fit the inclusion criteria of an intestinal biopsy taken at the time of corrective surgery and a complete medical history. The microscopic jejunal changes expected from the acute vascular compromise in these animals were diffuse edema, dilatation of lymphatics with possible lymphangiectasia, mucosal degeneration, diapedesis of neutrophils, and rare hemorrhage. These changes were discounted. Of the 23 biopsies, 14 (61%) were consistent with the presence of an underlying inflammatory disease, and of these 14, 12 (86%) were accompanied by case histories of prior gastrointestinal disturbances. This study raises the possibility of an association between GDV and inflammatory bowel disease.
Deep mycotic infections in cats
Authors: Davies C , Troy GC
Published: September 2014

A review of deep mycotic infections assessed incidence, signalment, clinical presentation, and outcome in 571 feline cases. Pertinent findings included a predisposition in young, male cats for Sporothrix schenckii and Blastomyces dermatitidis. There was an increased incidence of feline leukemia virus infection in cases with histoplasmosis and of feline panleukopenia virus infection in cases with either aspergillosis or mucoralosis. Few other predisposing conditions were identified. Cryptococcosis, coccidioidomycosis, and sporotrichosis had better prognoses for recovery. Blastomycosis, histoplasmosis, and aspergillosis commonly were disseminated infections and were associated with guarded-to-poor prognoses.
The use of a synthetic prostaglandin E1 analog as a gastric protectant against aspirin-induced hemorrhage in the dog
Authors: Bowersox TS , Lipowitz AJ , Hardy RM , Johnston GR , Hayden DW , Schwartz S , King VL
Published: September 2014

Misoprostol prevented gastric hemorrhage in dogs, each of which received aspirin (35 mg/kg body weight, orally q 8 hrs for 10 days). All dogs receiving aspirin alone had gastroscopic and histopathological lesions. No lesions were noted in four of five dogs given aspirin plus misoprostol (15 micrograms/kg body weight, q 8 hrs for five days; then 7.5 micrograms/kg body weight, q 8 hrs for five days). Four of 10 dogs receiving 15 micrograms/kg body weight of misoprostol developed diarrhea. The misoprostol dose was reduced to 7.5 micrograms/kg body weight, and the diarrhea subsided.
Comparison of thyrotropin-releasing hormone (TRH) to thyrotropin (TSH) stimulation for evaluating thyroid function in dogs
Authors: Frank LA
Published: September 2014

Five normal dogs and 22 dogs with dermatological signs suggestive of hypothyroidism were evaluated using thyrotropin-releasing hormone (TRH) and thyrotropin (TSH) stimulation. Thyroxine (T4) concentration after TRH stimulation was significantly lower than that obtained by TSH stimulation. It was not possible to identify hypothyroid dogs with the TRH-stimulation test, because some euthyroid dogs had either decreases in T4 or only slight increases in T4 concentrations after TRH stimulation. In addition, dogs with pyoderma had decreased responses in serum T4 after TRH stimulation, which became normal following treatment with antibiotics. Six of the 22 dogs were diagnosed as hypothyroid based on TSH results and responses to thyroid hormone replacement. It was concluded that TRH stimulation is not a useful means of diagnosing hypothyroidism in dogs.
Diagnosis, treatment, and temporary remission of disseminated paecilomycosis in a vizsla
Authors: March PA , Knowles K , Dillavou CL , Jakowski R , Freden G
Published: September 2014

A case of disseminated paecilomycosis in a three-year-old vizsla is described. Clinical signs of lethargy, weight loss, lymphadenopathy, diarrhea, and vestibulocochlear deficits were exhibited. Dense colonization of bone marrow by the fungus was found early in the disease course. Serial culture of bone-marrow aspirates and in vitro sensitivity testing helped monitor disease progression and guide antifungal therapy. Clinical and laboratory parameters demonstrated marked improvement for a period of 12 weeks. Multisystemic disease with central nervous system involvement was found at necropsy.
Semirigid external fixation for repair of fractures in young animals
Authors: Shamir MH , Shahar R , Johnston DE
Published: September 2014

An alternative method for external coaptation of fractures in young animals utilizes tongue depressors incorporated in a bandage consisting of a thick layer of cotton padding, gauze bandaging, and adhesive tape. This method was used in 13 cases with fractures of the tibia or the radius and ulna, some of which were open. Five cases (four dogs and a cat) had displaced fractures, and eight cases had either nondisplaced or only mildly displaced fractures. Size of the animal was not considered a limiting factor. Bandages were examined periodically. All fractures healed uneventfully, and the splints were removed 21-to-44 days after application. This method of external coaptation proved to be easy to apply and modify during the healing process and was applicable to a wide variety of fractures with good results.
Lateral exploration of fistulas developing after total ear canal ablations: 10 cases (1989-1993)
Authors: Holt D , Brockman DJ , Sylvestre AM , Sadanaga KK
Published: September 2014

A lateral approach was used successfully in seven of 10 dogs to resolve fistulas which developed after total ear canal ablations and bulla osteotomies. The approach facilitated identification and removal of horizontal ear canal remnants in four of the 10 cases. Facial nerve function was worsened temporarily by lateral exploration in two cases. Seven cases had no fistula recurrence during follow-up, which ranged from 12 to 72 months. Three cases each had fistula recurrence one-to-two months after fistula exploration.
Immunoglobulin A and immunoglobulin G biclonal gammopathy in a dog with multiple myeloma
Authors: Peterson EN , Meininger AC
Published: September 2014

A nine-year-old golden retriever was referred for evaluation of chronic anorexia, vomiting, and diarrhea. Low body weight, mucous membrane pallor, and palpably enlarged liver and spleen were detected by physical examination. Anemia, hyperglobulinemia, and concurrent trichuriasis and coccidiosis were identified upon initial diagnostic evaluation. Punctate vertebral lysis was apparent radiographically. Atypical plasma cell proliferation was found in the bone marrow, liver, and spleen. An immunoglobulin A and immunoglobulin G biclonal gammopathy was demonstrated by serum protein electrophoresis and immunoelectrophoresis. The dog was diagnosed with multiple myeloma and euthanized per owner request. Multiple myeloma should be considered in the differential diagnosis for biclonal gammopathy in the dog.
Nutritional support for rabbits using the percutaneously placed gastrostomy tube: a preliminary study
Authors: Smith DA , Olson PO , Mathews KA
Published: September 2014

A feeding-tube gastrostomy technique used in dogs and cats has been adapted to the rabbit. A detailed description of the percutaneous, incisionless placement of a gastrostomy tube using a gastroscope is presented. Management of the feeding tube and the formulation of a liquid diet for rabbits also are described. The percutaneous endoscopical gastrostomy (PEG) tube was used successfully to administer enteral nutritional support to the rabbit.
Clinical evaluation of tube esophagostomy in small animals
Authors: Devitt CM , HB3rd Seim
Published: September 2014

An alternative technique for placement of tube esophagostomy in small animals is described. Tube esophagostomy was placed in 13 dogs and nine cats. The mean duration of tube placement was 23 days (range, one to 48 days). No significant complications related to the tube were noted. In each case, tube esophagostomy was tolerated and time to healing of the esophagostomy site following tube removal was less than two weeks. Tube esophagostomy is suitable for use in a nutritionally compromised small animal with a functional esophagus and gastrointestinal tract.
Duplex Doppler estimation of resistive index in arcuate arteries of sedated, normal female dogs: implications for use in the diagnosis of renal failure
Authors: Rivers BJ , Walter PA , Letourneau JG , Finlay DE , Ritenour ER , King VL , O'Brien TD , Polzin DJ
Published: September 2014

The resistive index (RI), an ultrasonographic method of evaluating intrarenal resistance to blood flow, may be used to aid in diagnosis of renal failure. Values for arcuate artery RI, expressed as mean +/- two standard deviations, were obtained in clinically normal female dogs sedated with atropine, acepromazine maleate, diazepam, and ketamine hydrochloride. No statistically significant differences were noted between the values for the right kidney (0.33 to 0.57) versus the left kidney (0.32 to 0.56); however, the values were statistically significantly lower than values reported for nonsedated, normal dogs.
Experimental evaluation of central venous pressure monitoring in the dog
Authors: Oakley RE , Olivier B , Eyster GE , Hauptman JG
Published: September 2014

The measurement of central venous pressure (CVP) will provide objective information about intravascular blood volume. Limitations exist with direct and indirect methods of measuring CVP; however, the purpose of this study was to determine if such factors as catheter size, patient position, or measurements taken with either a water manometer or a strain-gauge transducer would affect the accuracy of CVP measurements. The study population consisted of six adult, mixed-breed dogs. Catheter sizes evaluated were 16- and 19-gauge. Patient positions evaluated were right and left lateral recumbencies. Right atrial pressures (RAPs) were used as the reference standards for CVP measurements. Measurements of RAP and CVP were obtained with a water manometer and a strain-gauge transducer. No significant differences were observed in measured CVPs for the effects of catheter size and right versus left lateral recumbency. A 2.7-mmHg difference in water manometry was demonstrated when compared to strain-gauge transducer measurements. Also, strain-gauge transducer measurements had less precision compared to water manometer measurements.
The sartorius muscle flap in the cat: an anatomic study and two case reports
Authors: Sylvestre AM , Weinstein MJ , Popovitch CA , Brockman DJ
Published: September 2014

The sartorius muscle in the cat is a broad, sheet-like muscle which covers the craniomedial aspect of the thigh. The major portion of the blood supply arises from the proximal pole of the muscle. A single sartorius muscle can be positioned over the abdomen in a transverse manner along the pubis, to cover the entire (i.e., left and right sides) caudal 30% of the abdomen. It also can be extended in a cranial-to-caudal fashion where it covers approximately 80% of the length and 75% of the width of the ipsilateral abdomen. The sartorius muscle flap is easy to harvest and provides good coverage for defects of the caudal abdominal wall. This muscle flap was used successfully in two feline patients.
Subarachnoid cyst in a cat
Authors: Shamir MH , Shahar R , Aizenberg I
Published: September 2014

A five-year-old domestic longhair was presented with hind-limb ataxia and some degree of incontinence of two weeks' duration. An enlarged spinal canal from the twelfth thoracic (T12) vertebra to the third lumbar (L3) vertebra was identified on survey radiographs. An intradural-extramedullary cavity at the twelfth (T12) and thirteenth (T13) thoracic vertebrae, filled with contrast material, was demonstrated on myelography. A left-sided hemilaminectomy was performed over this region, and a subarachnoid cavitation or cyst was found to be the cause of the severe spinal-cord compression. The cyst was drained. The cat showed improvement in the neurological signs during the first three weeks postoperatively. Six months later, no neurological deficits were identified on follow-up examination.
Hepatocellular necrosis associated with the subcutaneous injection of an intranasal Bordetella bronchiseptica-canine parainfluenza vaccine
Authors: Toshach K , Jackson MW , Dubielzig RR
Published: September 2014

A three-year-old wire fox terrier inadvertently was given an intranasal Bordetella bronchiseptica and canine parainfluenza vaccine subcutaneously. The dog subsequently developed both a local inflammatory reaction at the injection site and acute, nonseptic hepatocellular degeneration and necrosis. The patient was treated successfully with intravenous fluids and amikacin. Two months after the injection, the serum bile acid concentrations and hepatic histopathology indicated the presence of continued hepatocellular disease.
Onychectomy as a therapy for symmetric claw and claw fold disease in the dog
Authors: Boord MJ , Griffin CE , Rosenkrantz WS
Published: September 2014

Chronic onychodystrophies are a group of diseases that are frustrating and potentially expensive to manage. Despite appropriate diagnostics, an underlying etiology may not be identified. Long-term therapy may result in resolution or remission; however, relapses are common. In many cases, the disease persists in the face of appropriate therapy. Seven dogs with chronic onychodystrophies were treated with onychectomies. Treatment resolved the clinical signs for a follow-up period of four months to six years.
Primary cutaneous coccidioidomycosis and subsequent drug eruption to itraconazole in a dog
Authors: Plotnick AN , Boshoven EW , Rosychuk RA
Published: September 2014

Three weeks after traveling to Arizona, a 13-month-old, female Labrador retriever developed draining tracts in the right hind limb. Primary cutaneous coccidioidomycosis was diagnosed. Initial treatment with itraconazole resulted in exacerbation of clinical signs. Histopathology was suggestive of a cutaneous drug eruption. Discontinuation of the itraconazole caused resolution of the drug eruption. Successful treatment of the fungal infection was achieved using ketoconazole.
Acalculous cholecystitis in four canine cases: ultrasonographic findings and use of ultrasonographic-guided, percutaneous cholecystocentesis in diagnosis
Authors: Rivers BJ , Walter PA , Johnston GR , Merkel LK , Hardy RM
Published: September 2014

Canine cholecystitis is diagnosed infrequently. Clinical signs, physical examination findings, and clinicopathological abnormalities are nonspecific. Few reports exist of associated ultrasonographic findings which also are nonspecific for the disorder. Ultrasonographic-guided, percutaneous cholecystocentesis has been suggested for diagnostic confirmation. The present report further documents ultrasonographic findings associated with canine acalculous cholecystitis and demonstrates the utility of ultrasonographic-guided, percutaneous cholecystocentesis in confirmation of the diagnosis in a prospectively acquired clinical case series.
Massive gastric hemorrhage induced by buffered aspirin in a greyhound
Authors: Shaw N , Burrows CF , King RR
Published: September 2014

A 13-year-old, neutered male greyhound was presented with severe hematemesis and hematochezia following only three doses of buffered aspirin that were within therapeutic recommendations. Transfusion of seven units of whole blood was required to stabilize the patient. Diagnostic evaluation failed to reveal an underlying disease state that could have predisposed the dog to massive gastric hemorrhage. This is the first report of buffered aspirin causing clinically significant disease during routine administration.
Evaluation of weight loss protocols for dogs
Authors: Laflamme DP , Kuhlman G , Lawler DF
Published: September 2014

Several canine weight loss protocols were evaluated to determine their relative safety and efficacy. Dogs were fed 100%, 75%, 60%, or 50% of maintenance energy requirements (MERs) using the dogs' target body weights. No indications of adverse health effects were observed with any weight loss protocol. Triiodothyronine (T3) levels and apparent MERs decreased in dogs restricted to 50% to 60% of their MERs. The rate of weight loss was correlated linearly with degree of calorie restriction, although there was considerable individual variation. Percent overweight by the end of the test was not different between protocol groups for dogs fed 50%, 60%, or 75% of MERs. Therefore, any of the protocols tested in this study may be used in the management of overweight dogs; however, individual responses will be expected to vary, and severe calorie restriction may predispose dogs to weight rebound.
Bronchial rupture and fatal tension pneumothorax following routine venipuncture in a kitten
Authors: Godfrey DR
Published: September 2014

A five-month-old Siamese kitten suffered a bronchial tear and subsequently a fatal tension pneumothorax during routine venipuncture. No other injuries and no underlying diseases were identified upon gross postmortem and histopathological examinations. The pathogenesis of the bronchial tear was undetermined. Bronchial ruptures are unreported in animals; they are well recognized as rare injuries in humans with chest trauma. The pathogenesis of the bronchial rupture most likely was due to occlusion of the upper airways (directly or due to laryngospasm), along with pressure on the chest, or due to stretching and twisting of the tracheobronchial tree.
Resolution of superficial necrolytic dermatitis following excision of a glucagon-secreting pancreatic neoplasm in a dog
Authors: Torres SM , Caywood DD , O'Brien TD , O'Leary TP , McKeever PJ
Published: September 2014

An 11-year-old, neutered male standard poodle was diagnosed with superficial necrolytic dermatitis and a glucagon-secreting pancreatic islet neoplasm based on clinical, biochemical, histopathological, immunohistochemical, and hormonal findings. Hyperglucagonemia, hyperinsulinemia, and hypoaminoacidemia were observed on preoperative laboratory analysis. Abnormal laboratory values returned to normal, and complete resolution of skin lesions occurred after tumor excision. The dog has remained clinically normal for six months following surgery.
Metastatic carcinoma presenting as hind-limb lameness: diagnosis by synovial fluid cytology
Authors: Meinkoth JH , Rochat MC , Cowell RL
Published: September 2014

A dog presented for evaluation of left hind-limb lameness and pain associated with manipulation of the tail. Synovial metastasis of a carcinoma was diagnosed by joint fluid examination. A primary bronchiolar-alveolar carcinoma with widespread (including synovial and skeletal) metastases was diagnosed on postmortem examination. Metastasis to synovial surfaces is uncommon, but when it occurs, the metastasis-induced arthritis may be the initial presenting complaint for which medical attention is sought. Although rarely reported, cytological examination of synovial fluid may be diagnostic. This paper presents an interesting clinical case and reviews the literature concerning metastatic disease of the synovium.
Digital pad transposition for replacement of the metacarpal or metatarsal pad in dogs
Authors: Olsen D , Straw RC , Withrow SJ , Basher AW
Published: September 2014

A technique for digital pad transposition is described and illustrated. This technique has application for use in cases of metacarpal or metatarsal pad neoplasia or severe trauma. The transposed digital pad will provide a weight-bearing surface of heavy, keratinized epidermis in cases where the normal metacarpal or metatarsal footpad has been removed. The use of the technique in four clinical cases of footpad neoplasia also is reported.
Stellate rhytidectomy: superior entropion repair in a dog with excessive facial skin
Authors: Stuhr CM , Stanz K , Murphy CJ , McAnulty J
Published: September 2014

A four-year-old Chinese shar pei was presented for entropion repair that had not been corrected adequately with two prior Hotz-Celsus procedures. The primary cause for the failure was the weight of the excessive, superior facial folds often found in this breed. A new technique is presented to measure and remove these folds in a stellate pattern by following natural stress lines, thus effecting surgical repair of the superior lid entropion.
German shepherd dog pyoderma: a prospective study of 12 dogs
Authors: EJJr Rosser
Published: September 2014

Twelve German shepherd dogs, each diagnosed as having a recurrent or refractory deep pyoderma (i.e., German shepherd dog pyoderma [GSP]), were evaluated for several parameters over a six-year period. Results indicated that GSP could be associated with flea allergy dermatitis, atopic dermatitis, food allergy, cell-mediated immunodeficiency, or hypothyroidism, or could be an idiopathic disease. The combination of diseases present for a given dog varied from case to case. Adequate control of the pyoderma was achieved only after each identified underlying disease was treated specifically, along with aggressive concurrent medical therapy using systemic antibiotics and medicated baths.
Survival and prognostic factors in 189 dogs with dilated cardiomyopathy
Authors: Tidholm A , Svensson H , Sylven C
Published: September 2014

A survival analysis was performed using the case records of 189 dogs, including 38 breeds, with congestive heart failure caused by dilated cardiomyopathy (DCM). Overall prognosis was poor, with survival rates of 17.5% at one year and 7.5% at two years. Prognosis in the individual case of DCM proved to be difficult to predict at the time of initial examination. Only three of 27 tested independent predictors of survival were identified. The most significant predictive variables were age at onset of clinical signs, followed by dyspnea and ascites (as noted on the physical examination).
Nephrotic syndrome resulting in thromboembolic disease and disseminated intravascular coagulation in a dog
Authors: Ritt MG , Rogers KS , Thomas JS
Published: September 2014

Thromboembolic disease and progression to disseminated intravascular coagulation (DIC) are potential life-threatening complications for dogs with nephrotic syndrome. Platelet count, prothrombin time (PT), activated partial thromboplastin time (APTT), plasma concentration of fibrinogen degradation products (FDPs), antithrombin III (ATIII), protein C, and plasminogen were used to identify hemostatic abnormalities in a dog with nephrotic syndrome. Pulmonary thromboembolic disease was diagnosed by thoracic radiography, arterial blood gas analysis, and pulmonary scintigraphy. Prompt recognition and treatment of hemostatic complications is necessary in dogs with nephrotic syndrome.
Esophagostomy tubes for feeding and decompression: clinical experience in 29 small animal patients
Authors: DTJr Crowe , Devey JJ
Published: September 2014

Esophagostomy tubes were placed surgically in 13 dogs and 16 cats. The placement technique used was rapid and only required curved forceps, a scalpel blade, and suture material. Flexible tubes (5- to 30-French) were used for feeding liquids or blenderized diets for up to 557 days. Additionally, esophageal and gastric decompression were accomplished using these tubes. Following tube removal, all ostomy wounds healed by second intention without evidence of esophageal stricture or esophagocutaneous fistula. Complications included kinking, placement in an inappropriate location, obstruction, inflammation or infection of the ostomy site, and reflux of feedings.
Idiopathic, asymptomatic thrombocytopenia in Cavalier King Charles spaniels: 11 cases (1983-1993)
Authors: Smedile LE , Houston DM , Taylor SM , Post K , Searcy GP
Published: September 2014

The medical records of 11 Cavalier King Charles spaniels with idiopathic, asymptomatic thrombocytopenia and large-to-giant platelets were identified from a 10-year retrospective search using the Veterinary Medical Data Base at Purdue University. Eight of the dogs had been treated with various immunosuppressive drugs. Six of the treated dogs remained thrombocytopenic, one was not reevaluated, and one developed a normal platelet count. The underlying etiology of idiopathic, asymptomatic thrombocytopenia in Cavalier King Charles spaniels has not been identified, but this condition could represent a congenital macrothrombocytopenic disorder.
Thrombocytopenia in dogs with anticoagulant rodenticide-induced hemorrhage: eight cases (1990-1995)
Authors: Lewis DC , Bruyette DS , Kellerman DL , Smith SA
Published: September 2014

Thrombocytopenia was documented in eight of 11 dogs with anticoagulant rodenticide-induced hemorrhage. Thrombocytopenia was transient and generally mild-to-moderate, but it became marked (i.e., less than 30,000 platelets/microl) in two cases. Petechial hemorrhages were not noted in any case. There was no relationship between hematocrit and platelet count. Platelet count changes in response to treatment with fresh-frozen plasma and isotonic electrolyte solutions were variable. Anticoagulant rodenticide toxicity should be included as a differential diagnosis for dogs with hemorrhage accompanied by mild-to-moderate thrombocytopenia.
Thoracolumbar intervertebral disk disease in large, nonchondrodystrophic dogs: a retrospective study
Authors: Cudia SP , Duval JM
Published: September 2014

Medical records of 62 large, nonchondrodystrophic dogs diagnosed with thoracolumbar intervertebral disk disease between March 1986 and February 1996 were reviewed. Fifty-seven (92%), primarily mixed-breed dogs (mean age, 6.6 years) had Hansen type I disease. Fifty-eight percent had acute onset. The interspace between the first (L1) and second (L2) lumbar vertebrae was affected most commonly. The outcomes of the 48 dogs available for follow-up after undergoing laminectomies were evaluated. Surgical success rate and mean time to walking for nonambulatory dogs with deep pain perception was 90% and seven weeks, respectively. Thirty-nine percent had residual deficits. Following surgery, 12% had recurrence of disk protrusion/extrusion at a different site.
Successful treatment of uterine torsion and fetal retention in a postparturient Great Pyrenees bitch with septic peritonitis and prothrombotic complications
Authors: Ritt MG , Fossum TW
Published: September 2014

The treatment and favorable outcome of a bitch with uterine torsion and two retained fetuses are described. The condition was corrected surgically by ovariohysterectomy. Complications (i.e., septic shock, peritonitis, and hemostatic abnormalities) were managed with aggressive medical therapy. Torsion of the gravid uterus in dogs is a life-threatening condition which can have a successful outcome if medical complications encountered in the pre- and postoperative periods are treated quickly and effectively.
The use of enalapril in the treatment of feline hypertrophic cardiomyopathy
Authors: Rush JE , Freeman LM , Brown DJ , FWJr Smith
Published: September 2014

The clinical response to enalapril in 19 cats with hypertrophic cardiomyopathy (HCM) was evaluated retrospectively. Eleven cats were in congestive heart failure (CHF) at the time enalapril was prescribed, while only one cat was in CHF when the cats were reexamined three-to-six months later. Significant changes in cardiac dimensions were identified echocardiographically. No adverse effects on blood pressure, serum creatinine, or potassium were noted. Although the preliminary data suggests that enalapril is well tolerated and may contribute to some improvements in cats with HCM, controlled, prospective studies are needed to prove the efficacy of enalapril in this disease.
Diagnosis of shoulder instability in dogs and cats: a retrospective study
Authors: Bardet JF
Published: September 2014

The glenohumeral joint is a remarkable articulation providing the greatest range of motion of any joint in the body. Glenohumeral stability results from several mechanisms, including those that do not require expenditure of energy by muscle ("passive mechanisms") and those that do ("active mechanisms"). Glenohumeral instability has been recognized in 47 shoulders of 45 dogs and one cat. Cases are presented because of chronic foreleg lameness. Shoulder joint pain is obviated by the orthopedic examination. Only 57% of the involved shoulders presented with degenerative joint disease. Signs of instability are recognized under anesthesia using a craniocaudal or mediolateral drawer sign or both. This report describes the radiographic and arthroscopic findings of shoulder instability. Arthroscopy of the shoulder joint allows identification of all intra-articular pathologies. Shoulder instability, not fully recognized in the past, appears to be the most common cause of shoulder lameness in the dog.
Physaloptera infection in 18 dogs with intermittent vomiting
Authors: Theisen SK , LeGrange SN , Johnson SE , Sherding RG , Willard MD
Published: September 2014

Physaloptera infections were diagnosed endoscopically in 18 dogs. Each case had vomiting as the primary clinical sign, and four cases had regurgitation as a concurrent sign. Fecal flotations, using magnesium sulfate solution, were performed in 12 of the 18 cases and were negative for Physaloptera eggs. In 12 of the 18 cases, only one worm was seen during endoscopic examination. Fifteen of 18 cases were treated with pyrantel pamoate, and 10 of 12 cases with follow-up had resolution of their vomiting.
The fluctuation of tear production in the dog
Authors: Berger SL , King VL
Published: September 2014

The fluctuation and variation in canine tear production were established by evaluating the results of daily Schirmer tear test I (STT I) and weekly STT I and Schirmer tear test II (STT II) conducted on healthy dogs. The objectives of the study were to determine the fluctuation in STT values in dogs and its significance on both a daily and weekly basis; to determine the magnitude of the measured differences; and to identify any factors that might influence the fluctuation in STT values or variations of normal values between different dogs. The results of the study indicate that fluctuations in the STT values occur on both a daily and weekly basis. The fluctuations were only biologically significant on a week-to-week basis. There are significant differences between STT I and STT II values in dogs. The results also indicate that weight has a significant effect on STT values, with higher values measured in dogs of increasing body weight.
The use of propofol as an induction agent for halothane and isoflurane anesthesia in dogs
Authors: Bufalari A , Miller SM , Giannoni C , Short CE
Published: September 2014

Cardiovascular, pulmonary, and quantitative electroencephalographic parameters were assessed in 12 anesthetized dogs to determine the compatibility of the injectable anesthetic propofol with halothane and isoflurane. No cases of apnea were observed during induction of anesthesia. An adequate level of anesthesia was established in each protocol as judged by both the lack of response to mechanical noxious stimuli (i.e., tail clamping) and evidence of reduction in total amplitude of brain wave activity. The initial propofol-mediated decrease in arterial blood pressure continued during either halothane (52.4%) or isoflurane (38%) anesthesia without a simultaneous increase in heart rate. The results of this study suggest that propofol, in combination with inhalant agents, can be used effectively and safely for canine anesthesia in veterinary practice.
Skeletal metastasis in feline mammary carcinoma: case report and literature review
Authors: Waters DJ , Honeckman A , Cooley DM , DeNicola D
Published: September 2014

Despite the highly malignant nature of feline mammary carcinoma, few cases of skeletal metastasis have been reported. In this paper, a case of feline mammary carcinoma with skeletal metastasis to a distal limb is presented. The pertinent literature on feline mammary carcinoma and bone metastases is reviewed. Although the metastases of carcinomas in dogs and humans usually exhibit a proximal skeletal distribution, cats are more likely to develop distal extremity lesions. Clinicians need to have an index of suspicion that skeletal metastases may be responsible for lameness in elderly cats. Further investigation of the comparative aspects of bone metastases in cats and other species may elucidate the factors that regulate the development of skeletal metastases.
A case of canine central nervous system cryptococcosis: management with fluconazole
Authors: Tiches D , Vite CH , Dayrell-Hart B , Steinberg SA , Gross S , Lexa F
Published: September 2014

A three-year-old, female Labrador retriever was presented for acute generalized seizures. Disseminated cryptococcosis with central nervous system (CNS) involvement was diagnosed by serum and cerebrospinal fluid (CSF) fungal titers, histopathological examination, and magnetic resonance imaging (MRI). Fluconazole therapy resulted in prolonged, substantial clinical improvement for a period of one year. This report documents the diagnosis of a case of cryptococcal meningoencephalitis and its management with the new antifungal agent, fluconazole.
Prevalence of prostatic cysts in adult, large-breed dogs
Authors: Black GM , Ling GV , Nyland TG , Baker T
Published: September 2014

The prevalence of prostatic cysts was evaluated in 85 adult, male dogs weighing more than 16 kg which were admitted for problems unrelated to the prostate gland. Urine culture and prostatic evaluation by ultrasonography were performed in all dogs. Prostatic cysts were identified in 12 (14%) of the 85 dogs. Cultures of prostatic cysts were positive in five (42%) of the 12 dogs. Nonclinical, aerobic bacteriuria was documented in 9% of the study population. Urine cultures correlated with prostatic cyst cultures in four of the five dogs that had positive prostatic cyst cultures. Results of this study indicate that the prevalence of prostatic cysts in adult, intact male dogs is approximately 14% and that approximately 42% are infected with bacteria.
Early diagnosis of familial nephropathy in English cocker spaniels
Authors: Lees GE , Helman RG , Homco LD , Millichamp NJ , Hunter JF , Frey MS
Published: September 2014

Two litters of English cocker spaniels (ECSs) produced by familial nephropathy (FN) carriers were evaluated to characterize the early features of this disease. Three puppies developed FN. Proteinuria, which began when these puppies were five-to-eight months old, was the first abnormality detected. Proteinuria persisted while each puppy's growth rate slowed, and renal function gradually deteriorated. The interval from onset of proteinuria to development of azotemia was two-to-nine months. Characteristic glomerular capillary basement membrane (GCBM) lesions were seen with transmission electron microscopy (TEM) of renal biopsy specimens obtained during this interval. Ultrastructural GCBM lesions progressed substantially during the interval from biopsy to necropsy. However, routine light microscopic findings did not allow definitive diagnosis of FN in either biopsy or necropsy specimens. Detection of FN can be accomplished by screening at-risk ECSs for proteinuria. Renal biopsies are required to confirm the diagnosis in dogs for which proteinuria cannot be explained otherwise. Percutaneous needle biopsy specimens sufficient for TEM must be used to examine the GCBM to make a definitive diagnosis.
Complications associated with the implantation of polypropylene mesh in dogs and cats: a retrospective study of 21 cases (1984-1996)
Authors: Bowman KL , Birchard SJ , Bright RM
Published: September 2014

Complications associated with implantation of polypropylene mesh in dogs and cats were evaluated retrospectively. Immediate postoperative complications were common (in 10 of 20 cases) but predominantly involved seroma formation which resolved with treatment. The only long-term (i.e., six months or more) complication identified was mass recurrence at the site of tumor resection (in seven of 14 cases). Recurrence was affected by resection size. The average number of ribs resected in cases of thoracic wall neoplasia (with and without mass recurrence) was 1.8 and 3.5, respectively. In this study, implantation of polypropylene mesh facilitated the reconstruction of large tissue defects and was not associated with any serious complications.
Spinal epidural empyema in two dogs
Authors: Dewey CW , Kortz GD , Bailey CS
Published: September 2014

Extensive, diffuse, epidural spinal cord compression was visualized myelographically in two dogs presented for rapid development of nonambulatory tetraparesis and paraplegia, respectively. Purulent fluid containing bacterial organisms was aspirated percutaneously under fluoroscopic guidance from the epidural space of each dog. One dog responded poorly to aggressive medical therapy, which included installation of an epidural lavage and drainage system. Both dogs were euthanized due to the severe nature of their disorder and the poor prognosis. Spinal epidural empyema (i.e., abscess) is a rare condition in humans and has not been reported previously in the veterinary literature. Spinal epidural empyema should be considered as a differential diagnosis in dogs presenting with painful myelopathies, especially when accompanied by fever.
The effects of stains and investigators on assessment of morphology of canine spermatozoa
Authors: Root Kustritz MV , Olson PN , Johnston SD , Root TK
Published: September 2014

Percentage and types of morphological abnormalities found in canine spermatozoa were evaluated by three investigators using three stains (Giemsa-Wright stain [Diff-Quik], eosin Y/nigrosin [Hancock], and eosin B/nigrosin [Society for Theriogenology morphology stain] with conventional light microscopy, compared to phase contrast microscopy on unstained samples. The percentage of spermatozoa with abnormal heads, midpieces, and tails varied by technique and by investigator. Average percentages of morphologically normal spermatozoa were significantly higher in samples stained with Diff-Quik and samples examined by phase contrast microscopy than in samples stained with Hancock or Society for Theriogenology morphology stains. No effect of investigator on the percentage of morphologically normal spermatozoa was assessed. Results suggest that staining or preparation technique may alter the morphology of canine spermatozoa artifactually.
Extradural spinal angiolipoma associated with bone lysis in a dog
Authors: Reif U , Lowrie CT , Fitzgerald SD
Published: September 2014

An extradural spinal tumor was diagnosed in a 12-year-old Labrador retriever that was presented with a one-week history of paraparesis. Myelography indicated a deviation of the spinal cord to the right side at the level of the second lumbar (L2) vertebra. The difference in length measuring the left and right sides of the L2 vertebra suggested a fracture of the vertebral body. Severe bone remodeling and an extradural mass were seen on computed tomography (CT). Clinical, radiographical, and histological findings are described and considered homologous to extradural angiolipomas described in the human literature.
Comparison of anesthetic and cardiorespiratory effects of diazepam-butorphanol-ketamine, acepromazine-butorphanol-ketamine, and xylazine-butorphanol-ketamine in ferrets
Authors: Ko JC , Smith TA , Kuo WC , Nicklin CF
Published: September 2014

Ten ferrets were used in a crossover study to determine the sedative effects of intramuscularly administered diazepam (3 mg/kg body weight)-butorphanol (0.2 mg/kg body weight)-ketamine (15 mg/kg body weight); acepromazine (0.1 mg/kg body weight)-butorphanol (0.2 mg/kg body weight)-ketamine (15 mg/kg body weight); and xylazine (2 mg/kg body weight)-butorphanol (0.2 mg/kg body weight)-ketamine (15 mg/kg body weight). All of the ferrets became laterally recumbent following the administration of each drug combination. The xylazine-butorphanol-ketamine combination induced significantly longer (p less than 0.05) durations of tail-clamp analgesia (mean+/-standard deviation [SD], 81.0+/-19.1 min versus 20.5+/-25.4 min and 30.0+/-26.9 min), dorsal recumbency (mean+/-SD, 94.6+/-13.6 min versus 75. 6+/-34.7 min and 55.2+24.8 min), and muscle relaxation suitable for endotracheal intubation (mean+/-SD, 67.1+/-23.0 min versus 7.0+/-22.1 min and 9.5+/-15.4 min) than the diazepam-butorphanol-ketamine and acepromazine-butorphanol-ketamine combinations, respectively. The recovery time from dorsal recumbency to standing was not significantly different among the three treatment groups. The heart rate was significantly lower in the xylazine-butorphanol-ketamine group; however, systolic blood pressure was not significantly different among the treatment groups. Ventilatory function was more depressed in the diazepam-butorphanol-ketamine and xylazine-butorphanol-ketamine groups than in the acepromazine-butorphanol-ketamine group. A period (approximately 45 minutes) of hypoxia was observed in the xylazine-butorphanol-ketamine-treated ferret. Of the three combinations evaluated in ferrets, xylazine-butorphanol-ketamine was concluded to be the most effective anesthetic combination. However, hypoxemia and ventricular arrhythmias were observed in the xylazine-butorphanol-ketamine-treated ferrets, so the effectiveness of the xylazine-butorphanol-ketamine combination should be weighed against its cardiorespiratory side effects.
The effect of intralesional bleomycin on canine acanthomatous epulis
Authors: Yoshida K , Watarai Y , Sakai Y , Yanai T , Masegi T , Iwasaki T
Published: September 2014

Four dogs with recurrent acanthomatous epulis (AE) were injected with bleomycin (5 mg) intralesionally once a week. In three cases, tumors were clinically indistinguishable within three-to-eight weeks. In the fourth case, the tumor disappeared after 10 weekly injections. Through the administration period of bleomycin, no adverse reactions were recognized in any case. Electron microscopic examination together with a decrease in the percentage of mitotic cells implied that bleomycin might inhibit deoxyribonucleic acid (DNA) synthesis of tumor cells.
Cutaneous horn and squamous cell carcinoma in situ (Bowen's disease) in a cat
Authors: Rees CA , Goldschmidt MH
Published: September 2014

Cutaneous horn and squamous cell carcinoma (SCC) in situ (i.e., Bowen's disease) were documented concurrently in a cat. The cat had multiple, crusted lesions and a cutaneous horn on the right dorsal lumbar area. All the crusted cutaneous lesions were diagnosed as SCC in situ. Other findings included the presence of a thymoma and hepatoma. This cat was tested, and results were negative for feline leukemia and feline immunodeficiency viruses. At necropsy (eight months after the initial diagnosis was made) the hepatoma had ruptured, resulting in exsanguination and death.