bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Employer Branding on College Students' Willingness to Apply: Exploring Social Media as a Moderator
Authors: Rai Ni Gusti Made , Ninglasari Sri Yayu , Wijaya Troy Theofilus
Published: November 2024

This study aims to investigate the influence of employer branding on the willingness to apply for a job at a startup company, using social media as a moderating variable. The respondents of this research are 409 third-year students from the top 10 universities in Indonesia. This study employs a quantitative method with a purposive sampling approach. It utilizes surveys and data analysis through PLS-SEM. The findings of this study indicate that five indicators of employer branding, namely interest value, social value, economic value, development value, and application value, have a significant impact on job application intention. Furthermore, the study also reveals that social media does not directly influence these aspects of employer branding, except application value. This research is expected to provide insights and a foundation regarding the impact of employer branding and the use of social media on job application intention for relevant companies.
Keywords: employer branding, social media, willingness to apply, start-up
Value Chain Analysis in the Film Industry: A Literature Review
Authors: Boediman Andi Surja , Pujawan Nyoman , Baihaqi Imam
Published: November 2024

The film industry has undergone significant transformation due to technological advancements and shifts in consumer behavior. The original value chain concept was introduced by Porter (1985), and has been widely adapted to represent activities within the film industry, including production, distribution, and exhibition. This study employs a literature review to uncover the evolution of the value chain and use it as a theoretical framework for the film industry, which includes understanding the value chain dynamics, assessing competitiveness, adapting to digitization, and employing the concept of value networks. The methodology involves a structured search strategy across diverse sources, supplemented by snowballing, aiming to extract insights into integrating the value chain model with the industry. The findings demonstrate that the value chain concept signifies interconnections among different stages of the film industry, enhancing value creation and competitive advantage, with effects on digitization and digital distribution. By recognizing the activities within the value chain, the film industry can strategically optimize its processes, adapt to evolving trends, and make informed decisions that increase competitiveness. By connecting theoretical foundations with practical implications, the findings of the study contribute to an enriched understanding of film industry dynamics, value creation, and competitive strategies, offering valuable insights to practitioners, researchers, and stakeholders.
Keywords: value chain, film industry, competitiveness, vertical integration, digital distribution
Detecting Geothermal Operational Asset Anomalies Using the Locality-Sensitive Hashing (LSH) Algorithm
Authors: Hamza Muhammad Vito , Simamora Fransisco T.P. , Meliala Efrata Pratenta , Ajie R. Fuad Satrio , Azizah Hanifah Nur , Mustofa Fajar Khamim , Suparyanto Adi
Published: November 2024

Geothermal power plants are crucial for sustainable energy generation, necessitating the reliable maintenance of their operating assets. This research proposes an approach for asset maintenance through anomaly detection using the Locality- Sensitive Hashing (LSH) algorithm. The accuracy and coverage of traditional anomaly detection approaches in geothermal power plants may be constrained by sensor monitoring systems. The LSH algorithm is used to improve detection skills and get a full understanding of the state of important assets. The proposed method utilizes historical sensor data collected during geothermal power plant operations. This data is transformed into hash codes using LSH, effectively capturing similarities between various operational states and asset conditions. By comparing the hash codes of the current operational state with a library of precomputed hash codes representing typical operating conditions, the LSH algorithm can identify deviations indicating potential irregularities. This facilitates early detection of anomalies, even in large-scale databases, enabling prompt maintenance interventions. The application of anomaly detection using the LSH algorithm provides benefits such as improved asset maintenance planning, reduced downtime, and increased operational safety. By leveraging data-driven analysis and the effectiveness of LSH, geothermal operators can detect faults early, enabling prompt interventions and optimizing reliability and efficiency. By leveraging historical sensor data and the efficient similarity approximation capabilities of LSH, the proposed approach enables early diagnosis of problems, improving maintenance planning and optimizing geothermal operations.
Keywords: geothermal assets, locality-sensitive hashing, asset condition, fault detection, reliability
Augmented Reality as an Assistive Tool for Learning How to Use Medical Devices
Authors: Harseno Ahmad Rieskha , Kuswanto Djoko , Samboro MY Alief , Maharany Gunanda Tiara , Arlianti Irna , Firmansyah Ahmad Nur , Fitri Rahmania Almira , Wicaksono Aris Kurnia , Haryanto Laurensius Windy Octanio
Published: November 2024

In education, especially in medicine and medical technology, augmented reality (AR) is a promising innovation that can support and enrich the learning process. This technology offers the ability to present complex information on medical devices more interactively, enhance understanding, and provide a practical experience as an alternative to using real devices. AR can be integrated into the process of learning how to use medical devices. In particular, AR can improve information retention, facilitate understanding of technical concepts, and reduce errors when students use medical devices in simulations. It also allows students to practice in a safe environment before dealing with real situations. Despite its great potential, the application of AR in the learning process of medical devices also has several challenges. The need for infrastructure and compatibility is one barrier from a technological perspective. Meanwhile, from a pedagogical perspective, training for teachers to utilize AR effectively is essential. However, despite these challenges, with the right approach, AR has the potential to increase user engagement, deepen understandings of concepts, and enrich the learning experience. Also, with the development of technology and increasing affordability, we posit that these barriers will lessen over time.
Keywords: AR, augmented reality, learning process, medical devices
The Integration of the Modern Kebaya with Gothic Aesthetics in a Womenswear Collection as an Embodiment of Women's Empowerment
Authors: Antoinette Monalisa , ‎ Angelina , Saffira Mega
Published: November 2024

This study examines the visual aspects of the discovery and modernization of Indonesian Kebaya. The Kebaya’s integration with the Gothic style is considered an example of its modernization. The combination of these two aspects, in addition to its innovative nature, serves as a means of preserving the cultural significance of Kebaya both domestically and globally. The Gothic style is a popular fashion trend among the younger generation. The Kebaya and Gothic styles share historical connections as they both served as emblems of women’s resistance and independence in previous eras. In terms of visual aesthetics, there are notable similarities between the Kebaya and Gothic styles, particularly in their use of lace fabric and form-fitting silhouettes. In addition to this, the examination of the Kebaya and Gothic style, frequently associated with women, suggests that the incorporation of Gothic elements into the modernization of the Kebaya can serve as a symbol of women’s emancipation. The present study employs a qualitative research methodologies, including a comprehensive literature review, trend analysis, and design and material explorations. The exercise produced a collection of ten distinct designs, each of which is manifested in four different product realisations. The collection encompasses a range of garments, including Kebaya shirts, pants, skirts, bralettes, and corsets. These pieces predominantly include black hues and exhibit fitting body forms. Additionally, they are decorated with metallic hardware accents and embellishments, which are applied to lace and denim fabrics. The purpose of this collection is to ensure the preservation of the Kebaya as an integral part of Indonesian culture while also allowing it to coexist with contemporary pop culture. This approach aims to maintain the relevance of the Kebaya in an ever-evolving and modern society.
Keywords: Kebaya, gothic, modernization, culture, preservation, fashion
Analyzing the Relationship Between Sense of Place and Behavioral Culture
Authors: Sampurno Endry Salsabila , Astuti Susy Budi
Published: November 2024

Sense of place is a theory that originated in the field of humanistic geography and has expanded into various academic disciplines, such as environmental psychology and architecture. The definition of sense of place is the process of the relationship between humans and a place, resulting from a complete perception of environmental conditions, including both the physical and social settings that provide an experience of that place. Sense of place has three primary parameters: physical setting, meaning, and activities. However, these three parameters are no longer relevant to the current situation because the factors contributing to the sense of place are not solely based on these three parameters. After reviewing the literature and data, researchers have found that in some places, one of these parameters may not be considered, even though some of the community still perceives that region/area as having a strong sense of place. This is driven by the evolving behavioral culture of the community. Even a person’s background and birth year can affect their sense of place. Gen Z and millennials, with their fast, efficient, and instant behavioral culture, may have different perceptions of the sense of place in a location compared to Gen X and baby boomers, who tend to prefer more traditional elements. After the analysis of various literature reviews, researchers presented the results in the form of a bubble diagram illustrating the relationship between the sense of place and behavioral culture.
Keywords: relationship, sense of place, behavioral culture, literature review
Retrospective Analysis of Pregnant Cases in Terms of Drug-Drug interactions and Teratogenic risks
Authors: Karakoç Metin Deniz
Published: November 2024

Objective: While teratogenic risks in pregnant women are frequently discussed, polypharmacy and drug-drug interactions (DDI) are topics with little known information. The aim of this study is to determine the polypharmacy status, DDI, and teratogenic risk profile during pregnancy.

Method: A retrospective cohort study was conducted covering the year 2023 on pregnant women who were referred for pharmacology consultation due to a history of drug use. Investigation of DDI was performed through the Micromedex and Medscape online query modules.

Results: It was found that 113 pregnant women used a total of 71 different active ingredient drugs from 24 diverse pharmacological groups. The average number of drugs used per individual was 2.97. Analgesics, antibiotics, and gastric acid inhibitors were the most used medications, respectively. 11.6% of the women had a comorbidity, and cardiovascular diseases were the most common. It was determined that 28.3% of women had a serious or moderate DDI. The rate of drugs in categories D and X, which are particularly risky in terms of teratogenicity, was found to be 40.8%.

Conclusion: In addition to teratogenic effects, polypharmacy and DDI are also significant risk factors in pregnant women. There is still a crucial need for evidence on the medications prescribed in pregnancy, how it specifically affects women with comorbidities, and related benefits and harms.
The Impact of Advertising on the Popularity of Music Works
Authors: Dehghaninasrabad Hamed
Published: November 2024

Not only is advertising a powerful tool for businesses and marketing, it also shapes consumers’ behavior in the music industry as well.
This article deals with the influence of traditional and digital advertising methods on the popularity of musical productions.
This research seeks to navigate the relationship between the intensity of advertising and the popularity of the music work through the examination of several case studies and data from different genres of music. It highlights the roles of several media channels and platforms including streaming services and social media in making songs go viral as well as the economic impacts on the musicians and record companies.
The study provides insight into the problem of excessive commercialization in a digital sphere as a consequence of modern overexposure of the music industry.
This article concludes with recommendations for maximizing the effects of advertising on musical productions’ popularity while maintaining artistic integrity.
Phenolic Compound Analysis and Antioxidant Properties of O. Alborosea
Authors: Erim Kader , Savcı Ahmet
Published: November 2024

The Onosma genus has been used as a treatment among the public for a long time. In this study, the content analysis and some biological activities of the plant O. Alborosea Fisch. & C.A.Mey. ssp. (O. alborosea) used in traditional medicine in our country were investigated. For this purpose, methanol and water extracts of the plant were taken and the total phenolic substance amount of each extract was determined by HPLC device. FRAP, CUPRAC reduction methods and DPPH, ABTS radical scavenging methods were used to determine antioxidant activities. According to the results of our study, it was determined that water and methanol extracts showed lower activity compared to standard antioxidants. It can be said that the reason for this is related to the ratio of the phenolic amount they contain. Since no antioxidant studies were found when the literature search related to the current plant species was conducted, it is thought that our study will guide other studies to be carried out with this plant species and is important in terms of protecting our plants, which are our genetic treasure, and transferring them to future generations.
Lipany 1434
Authors: Strzyż Piotr
Published: November 2024

Bitwa pod Lipanami jest uznawana za jedną z najważniejszych bitew w historii Czech – obok Suchych Krut (Dürnkrut) w 1278 r. oraz Białej Góry w 1620 r. Dnia 30 maja 1434 r. na polach w okolicy niewielkich wsi Lipany i Hřibý rozegrał się krwawy bój, który przesądził o upadku rewolucji husyckiej. Wojska koalicji antyhusyckiej w ciągu kilku godzin doszczętnie rozbiły – dotychczas uznawane za niepokonane – wojska husyckich radykałów, przypieczętowując ich koniec.
Dla historyków wojskowości szczególnie zajmujące jest wyjaśnienie, w jaki sposób oddziałom koalicyjnym udało się przeprowadzić skomplikowany i jednocześnie skuteczny plan. Rekonstrukcja przebiegu bitwy nie jest jednak zadaniem łatwym. Zachowane przekazy źródłowe, podobnie jak w przypadku wielu (albo i większości) bitew doby średniowiecza, mimo pozornej szczegółowości nie zawsze są w pełni wiarygodne i spójne ze sobą. Wciąż sporo kwestii pozostaje zagadką.
Bitwa pod Lipanami wyróżniła się na tle innych działań militarnych tego czasu zastosowaną taktyką. Husyci zwykle walczyli z armiami uszykowanymi na klasyczny, rycerski sposób walki – tabor husycki pełnił funkcję fortecy. Jednak pod Lipanami, gdy obie strony zastosowały tabor z ustawionych w rzędy wozów bojowych, zaszła potrzeba modyfikacji utartych schematów. Manewr pozorowanego odwrotu okazał się kluczem do odniesienia sukcesu przez stronę koalicyjną. Zmiana ta wprowadziła do dość już skostniałego kanonu pewne istotne novum. W ten sposób już w trzy dekady później, w czasach Jerzego z Poděbradu, wojska Królestwa Czech mogły z powodzeniem stawać w szranki z oddziałami króla-wojownika – Macieja Korwina. Można zatem zaryzykować stwierdzenie, że taktyka zastosowana pod Lipanami oznacza nowy model w wojskowości czeskiej u schyłku średniowiecza.
Assessing the Influence of Crop Diversification of Intercrops with Cotton on Growth and Yield Characteristics of Cotton
Authors: Kalyani D. Lakshmi , Krishna M. Siva Rama , Vardhan K. Mohan Vishnu , Venkataramanamma K. , Reddy B.V. Ravi Prakash , Venkateswarlu N.C. , Lavanya Y.
Published: November 2024

Background: Intercropping cotton with pulses and millets, forming a multi-tier system, has the potential to shift the cost-intensive cotton production system towards a more profitable and sustainable approach. The study aimed to explore suitable intercrop combinations for multitier cultivation in cotton under rainfed conditions. Methods: The experiment involved seven multi.tier Bt cotton intercropping systems and two sole Bt cotton treatments with different spacing tried in a randomized block design with three replications during the kharif seasons of 2020-21, 2021-22 and 2022-23. Result: The study showed significant effects of various multi-tier cropping systems on cotton’s growth attributes, yield traits and yield. Seed cotton equivalent yield varied between 864 to 1401 kg/ha in different intercropping systems. In comparison, sole Bt cotton yielded 1103 kg/ha and the farmer’s practice resulted in 827 kg/ha.
Adaptive Neural Control Design for Strict-Feedback Time-Delay Nonlinear Systems Based on Fast Finite-Time Stabilization: A Case Study of Synchronous Generator Systems
Authors: Wang Honghong ,   Editorial Office, Chen Bing , Lin Chong , Xu Gang
Published: November 2024

This study aims to investigate the finite-time control problem for a class of strict-feedback time-delay nonlinear systems with unknown functions. The control design is based on a fast finite-time practical stability criterion. Unknown nonlinear functions can be estimated using the universal approximation performance of neural networks. Finite-time control design is performed using adaptive backstepping technology. By performing closed-loop stability analyses and choosing appropriate Lyapunov–Krasovskii functionals, all signals in a closed-loop system can be bounded within a finite time. Subsequently, the proposed control method can be applied for the excitation control of synchronous generators. The effectiveness of the proposed method is verified using a numerical model of a single-machine power system.
Can Large Language Models Assess Serendipity in Recommender Systems?
Authors: Tokutake Yu ,   Editorial Office, Okamoto Kazushi
Published: November 2024

Serendipity-oriented recommender systems aim to counteract the overspecialization of user preferences. However, evaluating a user’s serendipitous response to a recommended item can be challenging owing to its emotional nature. In this study, we address this issue by leveraging the rich knowledge of large language models (LLMs) that can perform various tasks. First, it explores the alignment between the serendipitous evaluations made by LLMs and those made by humans. In this study, a binary classification task was assigned to the LLMs to predict whether a user would find the recommended item serendipitously. The predictive performances of three LLMs were measured on a benchmark dataset in which humans assigned the ground truth to serendipitous items. The experimental findings revealed that LLM-based assessment methods do not have a very high agreement rate with human assessments. However, they performed as well as or better than the baseline methods. Further validation results indicate that the number of user rating histories provided to LLM prompts should be carefully chosen to avoid both insufficient and excessive inputs and that interpreting the output of LLMs showing high classification performance is difficult.
A Hybrid Optimization Approach for 3D Multi-Camera Human Pose Estimation
Authors: Eguchi Masatoshi ,   Editorial Office, Obo Takenori , Kubota Naoyuki
Published: November 2024

This paper introduces a method for estimating 3D human joint angles using a hybrid optimization approach that integrates particle swarm optimization (PSO) with the steepest descent method for enhanced accuracy in both global and local searches. While advancements in motion capture technologies have made it easier to obtain 2D human joint position data, the accurate estimation of 3D joint angles remains crucial for detailed behavior analysis. Our proposed method first applies PSO to optimize the initial estimation of 3D joint angles from 2D joint positions. We further refine the estimation using the steepest descent method, improving the local search process. The convergence and accuracy of the algorithm are influenced by the grouping strategy in PSO, which is discussed in detail. Experimental results validate the effectiveness of our approach in enhancing the accuracy of 3D human pose estimation.
Defining the Cost of Arthroscopic Rotator Cuff Repair
Authors: Fedorka Catherine J. , Beck da Silva Etges Ana Paula , Best Matthew J. , Liu Harry H. , Zhang Xiaoran , Sanders Brett , Abboud Joseph A. , Fares Mohamad Y. , Kirsch Jacob M. , Simon Jason E. , Woodmass Jarret , Jones Porter , Haas Derek A. , Armstrong April D. , Srikumaran Uma , Wagner Eric R. , Gottschalk Michael B. , Khan Adam Z. , Costouros John G. , Warner Jon J.P. , O’Donnell Evan A. ,   the Avant-Garde Health and Codman Shoulder Society Value-Based Care Group
Published: November 2024

Background:

Rotator cuff repair (RCR) is a frequently performed outpatient orthopaedic surgery, with substantial financial implications for health-care systems. Time-driven activity-based costing (TDABC) is a method for nuanced cost analysis and is a valuable tool for strategic health-care decision-making. The aim of this study was to apply the TDABC methodology to RCR procedures to identify specific avenues to optimize cost-efficiency within the health-care system in 2 critical areas: (1) the reduction of variability in the episode duration, and (2) the standardization of suture anchor acquisition costs.

Methods:

Using a multicenter, retrospective design, this study incorporates data from all patients who underwent an RCR surgical procedure at 1 of 4 academic tertiary health systems across the United States. Data were extracted from Avant-Garde Health’s Care Measurement platform and were analyzed utilizing TDABC methodology. Cost analysis was performed using 2 primary metrics: the opportunity costs arising from a possible reduction in episode duration variability, and the potential monetary savings achievable through the standardization of suture anchor costs.

Results:

In this study, 921 RCR cases performed at 4 institutions had a mean episode duration cost of $4,094 ± $1,850. There was a significant threefold cost variability between the 10th percentile ($2,282) and the 90th percentile ($6,833) (p < 0.01). The mean episode duration was registered at 7.1 hours. The largest variability in the episode duration was time spent in the post-acute care unit and the ward after the surgical procedure. By reducing the episode duration variability, it was estimated that up to 640 care-hours could be saved annually at a single hospital. Likewise, standardizing suture anchor acquisition costs could generate direct savings totaling $217,440 across the hospitals.

Conclusions:

This multicenter study offers valuable insights into RCR cost as a function of care pathways and suture anchor cost. It outlines avenues for achieving cost-savings and operational efficiency. These findings can serve as a foundational basis for developing health-economics models.

Level of Evidence:

Economic and Decision Analysis Level III. See Instructions for Authors for a complete description of levels of evidence.
Collagenase Clostridium histolyticum Versus Needle Fasciotomy for Primary Metacarpophalangeal Dupuytren Contracture
Authors: Hauksson Ingi Thor , Havdal Morten Beier , Benth Jūratė Šaltytė , Hoelsbrekken Sigurd E. , Randsborg Per-Henrik
Published: November 2024

Background:

Collagenase Clostridium histolyticum (CCH) and percutaneous needle fasciotomy (PNF) are 2 treatment options for Dupuytren disease. The purpose of this study was to compare these 2 methods in terms of clinical and patient-reported outcomes.

Methods:

Eighty patients (median age, 72 years; 83% male) with a single-digit primary metacarpophalangeal (MCP) joint contracture of ≥30° were randomized to either CCH or PNF and followed for 5 years. The primary outcome was the difference in flexion-contracture reduction at the MCP joint from baseline to 2 years, with additional analysis examining the effect of the primary endpoint variable up to 5 years. Secondary outcomes included complications, grip strength, scores on the visual analogue scale (VAS) for pain, the shortened version of the Disabilities of the Arm, Shoulder and Hand, the brief Michigan Hand Questionnaire, Unité Rhumatologique des Affections de la Main, and a VAS for treatment satisfaction as well as recurrence and retreatments.

Results:

The mean MCP joint contracture was 48° at baseline and 2° at 5 years in the CCH group, and 50° at baseline and 7° at 5 years in the PNF group. The reduction in MCP contracture at 2 years was larger in the CCH group than in the PNF group, with a mean difference between the groups of 12° (95% confidence interval [CI], 1.5° to 22.3°; p = 0.026). At 5 years, this mean difference was reduced to 6° (−1.5° to 12.8°; p = 0.1). There was no difference between the groups in any patient-reported outcome scores or grip strength beyond 4 weeks, with the exception of the brief Michigan Hand Questionnaire at 5 years. Ten (25%) of the patients in the PNF group compared with no patient in the CCH group had recurrence (contracture of ≥30°) at the MCP joint at 2 years. At 5 years, 17 (42.5%) of 40 patients in the PNF group had been retreated compared with 4 (10%) of 40 in the CCH group (p < 0.001). The CCH group experienced more transient complications (stiffness and hematoma) during the first week and were more satisfied (VAS satisfaction) from 1 year to the 5-year follow-up.

Conclusions:

The main finding of this study is that CCH and PNF were equally effective in reducing MCP flexion contracture, but the correction of contracture lasted longer in the CCH group.

Level of Evidence:

Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Characterization charcoal and activated carbon from starry triggerfish (Abalistes stellaris) bone activated using zinc chloride to reduce Cr6+
Authors: Handayani Lia , Nurhayati Nurhayati , Syahputra Faisal , Thaib Azwar , Astuti Yayuk , Darmawan Adi , Mardhiah Ainal
Published: November 2024

Starry triggerfish bone is the leftovers of fish products, and the utilization as carbon active is still minimal. Fish bones are organic waste containing carbon; therefore, they could be utilized as adsorbents (charcoal and activated carbon). This study aims to determine the characteristics of charcoal and activated carbon produced from starry triggerfish bone. The study about making charcoal and carbon active from starry triggerfish bone waste has been conducted using combined physics and chemical activation. physics activation is conducted at temperatures of 500°C, 600°C, 700°C, 800°C (CFB-500; CFB-600, CFB-700 and CFB-800), then the chemical activation using ZnCl2 15% (AC-500, AC-600, AC-700 and AC-800). Finding charcoal and carbon active characteristics such as surface area, analysis composition chemistry and morphology using BET-Ads, X-ray diffraction (XRF), and scanning electron microscopy (SEM). Based on chemical composition, CFB-600 has a better proportion of impurities than other CFBs and ACs. The activated CFB-500 with an activator (AC-500) experienced a significant increase of surface. It was better compared to others that reached 73.07 m2/g, while in the other treatments, the increase of surface area from CFB to AC ≤40 m2/g. Thus, it can be concluded the increase in temperature is not directly proportional to the increase in surface area. The temperature of 500oC is the optimal temperature obtained in this study and has a significant increase in surface area and absorption efficiency of Cr6+ of 87.47%.
Designing of fruit waste-derived activated carbon through CO2-consuming and microwave- assisted preparation to enhance and understand its adsorption performance towards metal, metalloid and polymer species
Authors: Kukowska Sylwia , Nowicki Piotr , Szewczuk-Karpisz Katarzyna
Published: November 2024

The main aim of the study was to develop fruit waste-derived activated carbon of high adsorption performance towards metals, metalloids, and polymers by the use of CO2-consuming, microwave-assisted method. The authors investigate textural, surface chemistry, and elemental parameters of precursors (chokeberry seeds, black currant seeds, orange peels), biochars (BCs) and activated carbons (ACs) obtained from them. Furthermore, the adsorption mechanisms of metalloids (arsenic, selenium), metals (copper, cadmium) and macromolecular compounds (bacterial exopolysaccharide, ionic polyacrylamides) were studied in one- and two-component systems. ACs prepared via direct and indirect activation as well as through conventional and microwave heating were compared. Microwave heating favoured surface development and, consequently, enhance ability to bind ions or macromolecules. Direct biomass activation led to higher microporosity compared to indirect, two-stage one, whilst CO2-consuming activation increased aromaticity and hydrophobicity of the solids. In the selected systems, polymers favoured metal/metalloid adsorption limiting their bioavailability.
Real-World Outcomes and Predictors of Failure of Gonioscopy- Assisted Transluminal Trabeculotomy in a Large Glaucoma Cohort: A Multicenter Study
Authors: I Eduardo Akio Pereira , Franco Claudia Gomide Vilela de Sousa , Pereira Ana Claudia Alves , Teno Bruno , Neto Francisco Lucena , de Faria Bruno Mendes , Vieira Julia Maggi , Vianello Marcos Pereira , Kanadani Fabio Nishimura , Magacho Leopoldo
Published: November 2024

This retrospective, comparative, multicenter study aimed to evaluate the real-world outcomes and predictors of failure of Gonioscopy-assisted transluminal trabeculotomy (GATT) at 12 months in glaucoma patients. Predictors of failure of absolute success in bilateral cases (422 eyes of 308 patients) included pre-operative intraocular pressure (IOP; IRR = 1.02; p = 0.01), and pre-operative mean deviation (MD; IRR = 0.98; p = 0.007). The significant predictors of failure of relative success included binocularity (IRR = 4.05; p = 0.001) and pre-operative IOP (IRR = 1.04; p = 0.022). Only one eye per patient (308 eyes) was included in the second analysis. IOP reduced from 21.84 ± 7.96 mmHg to 11.97 ± 2.89 mmHg at 12 months; the number of hypotensive eye drop medications decreased from 3.07 ± 1.04 to 1.06 ± 1.08 (p <0.001 for both). The pre-operative IOP was a predictive factor for failure of absolute (IRR = 1.02; p = 0.026) and relative successes (IRR = 1.05; p = 0.014). The number of hypotensive medications only affected absolute success (IRR = 1.25; p = 0.004). The Kaplan–Meier graph revealed relative and absolute success in 88.9% and 43.9% of cases, respectively. No serious complications were observed in the study.
Primary adenocarcinoma of the lesser omentum: A Case Report
Authors: Xu Xing , Zhang Xue , Zhang Xiaoyang , Tuo Hongfang
Published: November 2024

Background:
Adenocarcinoma of the lesser omentum is a rare malignant tumor that develops between the hilar region of the liver, the lesser curvature of the stomach, and the upper area of the duodenum. Because of its rarity, unusual origin, and possibly diverse symptoms, this malignancy presents substantial diagnostic and therapeutic problems. Because signs of lesser omentum adenocarcinoma are infrequent and sometimes identified late in the disease's course, early identification and treatment are crucial for improving patient outcomes.
Case Summary:
We describe a 64-year-old woman with a physical examination who discovered a lesser omentum tumor with no early clinical symptoms. We used three-dimensional reconstruction to understand the complex anatomical relationships and extent of this rare malignant tumor, allowing us to accurately observe its size, location, and relationship with surrounding structures and develop a detailed surgical plan for the patient, which was successfully performed. We have followed up for 1 year so far and revealed no evidence of recurrence.
Conclusion:
Adenocarcinoma of the lesser omentum is extremely rare in clinics, and preoperative 3D reconstruction can visualize the lesion's blood supply. This allows the operator to design a reasonable surgical method before surgery, reducing operation time and maximizing patient benefit.
Elucidating the role of gut microbiota metabolites in Diabetes by employing network pharmacology
Authors: Yao Weiguo , Huo Jinlin , Ji Jing , liu Kun , Tao Pengyu
Published: November 2024

Background
Extensive research has underscored the criticality of preserving diversity and equilibrium within the gut microbiota for optimal human health. However, the precise mechanisms by which the metabolites and targets of the gut microbiota exert their effects remain largely unexplored. This study utilizes a network pharmacology methodology to elucidate the intricate interplay between the microbiota, metabolites, and targets in the context of DM, thereby facilitating a more comprehensive comprehension of this multifaceted disease.
Methods
In this study, we initially extracted metabolite information of gut microbiota metabolites from the gutMGene database. Subsequently, we employed the SEA and STP database to discern targets that are intricately associated with these metabolites. Furthermore, we leveraged prominent databases such as Genecard, DisGeNET, and OMIM to identify targets related to diabetes. Protein-Protein interaction (PPI) network was established to screen core targets. Additionally, we conducted comprehensive GO and KEGG enrichment analyses utilizing the DAVID database. Moreover, a network illustrating the relationship among microbiota-substrate-metabolite-target was established.
Results
We identified a total of 48 overlapping targets between gut microbiota metabolites and diabetes. Subsequently, we selected IL6, AKT1, and PPARG as core targets for the treatment of diabetes. Through the construction of the MSMT comprehensive network, we discovered that these three core targets exert therapeutic effects on diabetes through interactions with 8 metabolites, 3 substrates, and 5 gut microbiota. Additionally, GO analysis revealed that gut microbiota metabolites primarily regulate oxidative stress, inflammation and cell proliferation. KEGG analysis results indicated that IL-17, PI3K/AKT, HIF-1, and VEGF are the main signaling pathways involved.
Conclusion
Gut microbiota metabolites primarily exert their therapeutic effects on diabetes through the IL6, AKT1, and PPARG targets. The mechanisms of gut microbiota metabolites regulating DM might involve signaling pathways such as IL-17 pathways, HIF-1 pathways and VEGF pathways.
Geotechnical Characteristics of Lime and Groundnut Shell Ash (GSA) Stabilised Soils for Road Building in Southwestern, Nigeria
Authors: Faluyi Sunday Olubunmi , Amu Olugbenga Oludolapo , Olofintuyi Ilesanmi Olanrewaju
Published: November 2024

The current and future condition of each layer of road depends primarily on the soil beneath its foundation. The condition of the roads in south-west Nigeria is deplorable; Most of these are impassable owing to pavement failure, necessitating analysis of the fitness of the underlying soil layers when stabilized with a peanut shell ash (GSA) mixture. Eighteen selected drill pit soil samples (one from each Senatorial district in south-western Nigeria) were utilized in this investigation while strength tests(California Bearing Ratio CBR, Unconfined Compressive Strength (UCS), Compaction and Triaxial) were also done to 6% lime and attempts to 100% GSA mixed soil samples in the laboratory using standard procedures. Chemical analysis was also carriedout on the local additives. The results of the study revealed that the GSA additive possessed a high SiO2 content, in addition all strength related attributes such as (CBR, maximum dry density (MDD), UCS, shear strength (τ), cohesion (c) and angle of internal friction (𝜙) increased with increasing GSA levels increase except optimum moisture content (OMC) which decreases. Virtually all unuseful soil samples were found useful for as paving course materials after stabilization. The mix of 6% optimum lime and 6% GSA grade is highly suggested for soil amendment, peculiarly for road building in southwest Nigeria.
A Rare Case of Intrathoracic Gauzoma
Authors: Adachi Taishi , Kayawake Hidenao , Hamakawa Hiroshi , Takahashi Yutaka
Published: November 2024

Background
Gauzoma is a foreign body reactive granuloma which is an extremely rare complication of thoracic surgery. We describe a case of a Gauzoma in which the gauzes were removed by video-assisted thoracoscopic surgery as a less invasive procedure, discovered incidentally after 35 years of follow-up.
Case presentation:
A 51-year-old man was referred to our department for hyperhidrosis treatment, and imaging studies and biopsy confirmed the diagnosis of Gauzoma. As the Gauzoma gradually grew for a few years, surgical intervention was judged necessary, and the removal of the gauzes was performed in this case. A two-stage operation in two days was required to complete the surgery. The completion of gauze removal was confirmed in the second surgery using a postoperative computed tomography (CT) scan. The patient is currently doing well 17 months after surgery, and the size of granuloma unchanged.
Conclusion
We performed the removal of the gauzes as the treatment for Gauzoma. Although removing the gauze may have prevented its growth so far, careful follow-up is still needed.
Influence of rock bolt reinforcement on shear behaviour of a nonpersistent joint plane
Authors: Xue Hongyun , Yang Xuxu , Kulatilake Pinnaduwa HSW , Qu Guanglin
Published: November 2024

The impact of rock bolts on the mechanical behavior of nonpersistent joints, including the intricate interactions between the joints, rock bridges, and rock bolts, has received limited investigation despite their effectiveness in reinforcing rock mass discontinuities. In order to tackle this issue, a variety of normal stresses were applied during direct shear tests conducted on artificial rock-like specimens with nonpersistent joints, both bolted and unbolted. The findings indicated that the local shear deformation-shear displacement curves, whether with or without rock bolts, can be categorized into five distinct stages. Application of the rock bolts on the nonpersistent joint plane resulted in making the following two important statements: (a) The rock bolts delay the shear stress transmission along the joint plane from the joint parts to the rock bridge area; (b) The rock bolts limit the dilatancy occurring in both the joint parts and at the rock bridge area. Furthermore, the shear displacement of the bolted nonpersistent joint specimen at the peak shear strength was found to be greater than that of the unbolted nonpersistent joint specimen indicating protection of the rock bridge by the rock bolts. Whether bolted or unbolted, the stiffness values seem to be the same for the nonpersistent joint plane for a selected normal stress; this observation is significantly different from that observed for the persistent joint plane.
Dentoskeletal Effects of Aesthetic and Conventional Twin Block Appliances in the Treatment of Skeletal Class II Malocclusion: A Randomized Controlled Trial
Authors: Alsilq Mohamed Najati , Youssef Mohamed
Published: November 2024

This clinical trial evaluate the skeletal and dentoalveolar changes resulting from a modified twin block (aesthetic twin block) (ATB) in comparison with conventional twin block (CTB). Two-arm parallel group randomized clinical trial was performed at Department of Orthodontics, University of Damascus, Syria. Fifty-two patients (33 females and 19 males) aged 12.23±0.77 years with skeletal class II division 1 malocclusion caused by mandibular retrognathism. The participants were randomly assigned to a study group according to a simple randomization method using a numbered and sealed envelope. The experimental group were treated with aesthetic twin block, and control group were treated with conventional twin block. Sixteen angular variables and eleven linear variables (measured in millimeters) were evaluated before the treatment (T0) and at the end of the active phase of the treatment (T1) on lateral cephalometric radiographs to study the skeletal and dentoalveolar changes. There was a statistically significant change in ANB angle between the ATB group (-2.70±0.84) and the CTB group (-1.92±0.81°) (P = 0·002), and SNB angle the ATB group (2.72±1.54°) and the CTB group (1.72±1.41°)(P = 0·02). The Jarabak ratio decreased significantly in the CTB group by (-0.65±1.37%) (P = 0.02) and increased significantly in the ATB group by (0.84±1.44%) (P =0.007), with significant differences between the two groups (P = 0.000). The change in upper incisor angulation was (0.36±5.91°) for the ATB group and (-3.5±4.18°) for the CTB group, which was statistically significant (P = 0·01). The change in lower incisor angulation was (1.34±2.08°) for the ATB group and 3.88±2.47° for the CTB group, which was statistically significant (P = 0·000). ATB had greater skeletal effectswith more control of vertical growth, and greater control of lower and upper incisor angulation.
Trial Registration: (NCT05418413) (14/06/2022).
Clinical features and Prognostic Factors of Patients with Primitive Neuroectodermal Tumors
Authors: Qu Xiang , Yang Jie , Wu Ming , Yang Xiaoliang , Tian Bozhen , Qiao Yu
Published: November 2024

Background
Primitive neuroectodermal tumors (PNET) are associated with poor prognosis, and their treatment remains a challenge. However, research on PNET patients is relatively limited. Therefore, we aim to investigate the prognosis of this specific cohort and identify independent prognostic factors.
Methods
This study screened a cohort of PNET patients from the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute from 2000 to 2020. Prognostic analyses were performed using the Kaplan-Meier method and Cox proportional hazards regression model.
Results
A total of 941 eligible PNET patients were included, with the most common site of occurrence being the brain (57.07%). The 5-year overall survival (OS) and cancer-specific survival (CSS) rates for the entire study population were 51.1% and 54.2%, respectively, while the 10-year OS and CSS were 44.7% and 48.7%, respectively. In the univariate analysis, age, marital status, tumor stage, surgery, and chemotherapy had significant impacts on patient survival outcomes. In the multivariate analysis, age and the presence of metastasis at initial staging were identified as independent poor prognostic factors for both OS and CSS, while surgery and chemotherapy were independent prognostic factors for OS, with surgery also being an independent prognostic factor for CSS.
Conclusion
Surgery combined with chemotherapy showed survival benefits for PNET patients and is recommended. Radiotherapy did not improve patient survival, which requires further investigation in future studies.
Strains of a Virtuoso: Pacemaker Infection and Ventricular Tachycardia in a Violinist
Authors: Chen Yuanguo , Zhang Haibo , Qiao Qi , Ma Lian
Published: November 2024

Purpose
Pacemaker-related infections are serious complications of cardiac implantable electronic devices (CIEDs)1–5. This case report aims to describe the occurrence of pacemaker pocket infection and recurrent ventricular tachycardia (VT) in a Chinese amateur violinist with sick sinus syndrome (SSS), and to explore the possible connection between occupational habits and the infection, as well as VT.
Methods
A 76-year-old male violinist with a Biotronik Evia DR dual-chamber pacemaker presented with syncope and signs of a pacemaker pocket infection three years after implantation. Despite initial antibiotic treatment, the infection persisted with slightly elevated C-reactive protein (CRP) and negative cultures. The VT originated from the right ventricular outflow tract (RVOT), as confirmed by echocardiography and ECG findings. The infection was treated with debridement and extraction of the pacemaker and leads.
Results
Debridement and extraction of the pacemaker and leads successfully resolved both the VT and the infection. The VT was likely linked to the infected lead, while the pacemaker infection was attributed to the patient’s violin playing, which caused mechanical stress and skin damage at the pacemaker site. Postoperative recovery was uneventful, with no recurrence of infection or arrhythmias at follow-up.
Conclusion
This case highlights the importance of considering a patient’s occupational habits when selecting pacemaker pocket sites to prevent infections and complications. In this case, the patient's violin playing likely contributed to mechanical stress at the pacemaker site, leading to infection. Early identification and appropriate management, including device removal, are crucial to prevent further complications.
The Assessment of Sub-Saharan Africa's GHG emission from cropland in comparison to some developing nations, its environmental economic impacts, and mitigation measures
Authors: Igwe Emmanuel
Published: November 2024

Croplands are one of the world's leading single major contributors to global greenhouse gas (GHG) emissions with more than 20% share of the emitted GHG, at the same time depending on the climate to produce its yields, this situation is significantly felt in Sub-Saharan Africa (SSA) due to the unavailability of mitigating technologies. Satellite image of sentinel-7 was deployed to capture real-time virtual images of land use land cover (LULC) showing a proportion (58%) of massive agricultural land in the region still lies uncultivated due to its losses to climate catastrophe that endangers and rendered between 0–40% usefulness for food production valueless. This study deploys various measuring metrics to examine the intensity of climate variability using panel data, as well as real-time data from remote sensing (RS) to verify and make a comparison of CO2eqKg emitting capacity from leading croplands major countries in SSA. Estimate stochastic frontier analysis (SFA) was used to compute and assemble from 1988 to 2022. The result revealed within the six closely monitored countries their emitting rate with South Africa led as the highest emitter of CO2 equivalent in kg in these years, with its peak annually recorded in 1990 at an estimated value of 64kg CO2eqKg followed by 2017 with a value of about 58 kg CO2eqKg while Ethiopia came second with its second-highest emitting rate in 2007 with a value of 24kg CO2eqKg followed by Nigeria with mean contributory value of 21Kg CO2eqKg. It unveiled an estimated total cropland of 10881657.5 square hectares in North central Tier 2 (Nigeria, Niger) and North central Tier 3 (Sudan, Ethiopia) as the hotspot of the GHG emission index. The study further presented 2013–2022 as the most diminution years in the region with a forecasted 21% ecological resources (aquatic species) decline in the coming year with a burden of more disastrous ecological resources in most likely affected nations such as Nigeria, South Africa, Kenya, Mali, and Burundi, Zambia as they are mapped as the most vulnerable to these unforeseen longtime environmental consequences. The study suggests adopting locally developed innovative technologies compatible with current climate resilience strategies, to be implemented through a comprehensive approach.