bluuebunny/crossref_metadata_2025 huggingface dataset:
Augmented reality (AR) technology on the android operating system in human respiratory system: From organ to cell
Authors: Rini Daniar Setyo , Azrai Eka Putri , Suryanda Ade , Inayah Shabrina Syifa , Khansa Anindya Annisa , Kurnianto Mathias Bagas
Published: April 2022

Understanding the object of learning material that is abstract is currently still an obstacle faced by students. The use of technology in learning is expected to reduce the obstacles faced by these students. Augmented reality (AR) is a technology that is currently being widely applied in the learning process because it is considered capable of helping students understand abstract learning materials with 3D object features. This study aims to design and develop AR, especially in the anatomical structure of organs in the human respiratory system, which is then integrated into biological practice in the laboratory. The AR application has been designed, created, validated, and published under AR Synapse (Augmented Reality Respiratory System). The AR application developed is based on the android system and has gone through validation tests by experts. Five expert validators who work as lecturers and high school teachers. Expert validation results with an average score of 3.6 from a maximum score of 4.0, which states that the AR Sinaps application is 91.2%, has functioned well, supports learning, provides objects relevant to teaching materials, and is considered to increase students' learning motivation. Furthermore, it has good prospects for continuous development. Students' satisfaction survey and user evaluation also gave a good response with an average rating percentage of 85.1%.
The Impact of COVID-19 on Year 13 A level Mathematics Students: findings of a small-scale survey
Authors: Price Charlotte Louise , Owen Alun , Lawson Duncan
Published: April 2022

In England, students who were awarded A levels in the summer of 2021 experienced disruption in their education during Years 12 and 13 (i.e., throughout the whole of their A level studies) due to the COVID-19 pandemic. National examinations were cancelled in 2021 (as in 2020) and students were given Teacher-Assessed Grades (TAGs). In determining these grades, teachers were instructed to judge students’ achievements in relation to the material that had been covered during Years 12 and 13 rather than against the complete A level syllabus. This small-scale study investigated potential impacts of the unusual experience of Year 13 A level mathematics students on factors including topics covered, confidence in mathematics, post-A level intentions and readiness for higher education, with a view to considering challenges around the transition to higher education. Data were gathered using student and teacher questionnaires. In total, 174 students and 27 teachers from 19 schools/colleges across the country (including one college in Wales) completed the questionnaires. This paper gives a high-level overview of the main messages emerging from the questionnaire responses. It is intended to undertake a more in-depth analysis of the data at a later date and report the findings from the more detailed analysis in subsequent papers.
Relación entre la inteligencia emocional y el apoyo social con el bienestar subjetivo: Un estudio transcultural España-Ecuador
Authors: Hidalgo-Fuentes Sergio , Martínez-Álvarez Isabel , Tijeras-Iborra Amparo , Sospedra-Baeza Mª Josefa
Published: April 2022

Marco teórico: la inteligencia emocional es una de las variables psicológicas más estudiadas en la actualidad, así como el apoyo social, que puede actuar como protector de la salud y el bienestar psicológico. El objetivo principal del trabajo es el estudio del impacto que la inteligencia emocional y el apoyo social percibido tienen en la felicidad subjetiva y la satisfacción vital en universitarios de dos culturas y contextos diferentes: España y Ecuador.

Método: 760 estudiantes universitarios, incluyendo 379 españoles (83.1% mujeres) y 381 ecuatorianos (76.6% mujeres), completaron las escalas Trait Meta Mood Scale, Multidimensional Scale of Perceived Social Support, Satisfaction With Life Scale y Subjective Happiness Scale. 

Resultados: a pesar de encontrar diferencias entre las muestras en cada variable, los análisis correlacionales muestran la existencia de relaciones estadísticamente significativas y positivas en ambas muestras entre las dimensiones de claridad emocional y reparación de las emociones, pertenecientes a la inteligencia emocional, tanto con la satisfacción vital como con la felicidad subjetiva, y en dimensiones del apoyo social percibido, siendo la familia un predictor tanto de la satisfacción con la vida como de la felicidad subjetiva.

Conclusiones: la presente investigación contribuye a una mayor comprensión de la influencia de la inteligencia emocional y el apoyo social sobre el bienestar subjetivo en dos culturas diferentes.
Construcción y validación de la Escala de Dependencia Emocional (EDE)
Authors: Jiménez-Cruz Blanca Elizabeth , Amare Pelayo Gabriela , Ledesma Ortega Karla Fernanda , Riveros Rosas Angélica
Published: April 2022

Se diseñó y validó un instrumento para evaluar dependencia emocional (DE) en población mexicana joven, tomando como referencia el CDE y el IDE. Participaron 559 estudiantes universitarios (50.1% mujeres y 49.9% hombres), con edades entre 17 y 26 años. Análisis factoriales exploratorios y confirmatorios revelaron la existencia de siete factores, con valores de confiabilidad interna adecuados para la escala completa (α = .92) y para sus subescalas (α entre .71 y .88). La escala mostró validez concurrente con una escala de violencia en el noviazgo (correlaciones entre r = .304 y r = .602) y con una escala de percepción de apoyo social (correlaciones entre r = -.179 y r = -.397). Se concluye que la EDE es una escala válida y confiable para evaluar la dependencia emocional hacia la pareja, por lo que supone ser un recurso útil para la medición de este fenómeno en población juvenil.
Psicología de la Salud: ¿para cuándo en la cartera de servicios?
Authors: Van-der Hofstadt Román Carlos J.
Published: April 2022

La pandemia del COVID-19 ha servido, entre otras cosas, para poner encima de la mesa las vergonzantes cifras alrededor de la atención a salud mental de la población. Así, durante un tiempo se ha conseguido estar de forma casi permanente en los medios de comunicación y desde muchas áreas, plantear la necesidad de abordar ésta problemática y tratar de resolverla, aunque sea de forma parcial. El lema “No hay salud sin salud mental”, ha estado presente de forma continuada en el tiempo en los diferentes medios de comunicación y redes sociales, y desde diferentes organizaciones se ha estado hablando de la necesidad de la incorporación de Psicólogos a Atención Primaria para facilitar el acceso de la población y la de incrementar el número de plazas en las convocatorias de Psicólogos Internos Residente dentro de la convocatoria de Formación Sanitaria Especializada del Ministerio de Sanidad.
Violencia de pareja en adolescentes y adultos maltratados en la infancia: Papel mediador del TEPT
Authors: Fernández-Marrero Aliety , Costa López María del Mar
Published: April 2022

Tanto el maltrato infantil como la violencia de pareja representan un grave problema de salud pública que afecta cada año a millones de personas en todo el mundo. En este artículo hacemos una revisión de la literatura, señalando las asociaciones directas e indirectas entre estas dos variables. La teoría y la investigación se han centrado en explicar los posibles enlaces teóricos entre el maltrato infantil y la perpetración de violencia de pareja y se ha sugerido que puede operar, de modo indirecto, a través de los síntomas de TEPT. El presente artículo se centra en el papel mediador del TEPT entre el maltrato infantil y la violencia de pareja, lo cual tiene implicaciones importantes para guiar futuras investigaciones sobre estos temas y diseñar programas de prevención y tratamiento.
Adaptación al asma bronquial en pediatría: ansiedad y bienestar psicológico
Authors: Ribera-Asensi Olga , Valero-Moreno Selene , Castillo-Corullón Silvia , Pérez-Marín Marián
Published: April 2022

Marco teórico: el asma bronquial es la enfermedad crónica más prevalente en la infancia y adolescencia. Su presencia es un factor de riesgo para desarrollar un trastorno psicológico, siendo la ansiedad la sintomatología más común en estos pacientes. Por otro lado, el bienestar psicológico es un factor de protección para un adecuado ajuste a la enfermedad. Nuestro objetivo es analizar los niveles de ansiedad y de bienestar psicológico en adolescentes con asma bronquial.Método: la muestra incluye 73 adolescentes asmáticos de 9 a 18 años. Se analizaron las variables Ansiedad (HADS) y Bienestar Psicológico (BIEPS-J) mediante análisis descriptivos, pruebas t para muestras independientes y correlaciones de Pearson.Resultados: un tercio de la muestra presenta niveles elevados de ansiedad (diagnóstico probable= 9,60%; caso probable= 26%). Las medias obtenidas en la escala BIEPS-J fueron altas, encontrando diferencias significativas en el factor “aceptación de sí mismo” (t=2,42, p=,02, d=,57), siendo mayor en los hombres. No se han encontrado relaciones significativas entre las variables.Conclusiones: resulta necesario esclarecer los factores que influyen en la existencia de niveles elevados de bienestar psicológico en dichos pacientes y tomar medidas sanitarias de prevención multidisciplinares con el fin de detectar tempranamente la presencia de ansiedad y tomar actuaciones psicológicas pertinentes.
Participación social y satisfacción vital: tipos de participación y diferencias entre mujeres y hombres mayores
Authors: Pinazo-Hernandiz Sacramento , Torregrosa-Ruiz Manuela , Jimenez-Marti Maria , Blanco-Molina Mauricio
Published: April 2022

La participación social de las personas mayores contribuye a la calidad de vida y fomenta el envejecimiento activo y saludable. El presente estudio investiga si existen diferencias por sexo en participación social, así como en la asociación entre la participación social y la satisfacción con la vida. Método. Diseño transversal de encuesta. Muestra: personas mayores de 55 o más años, estudiantes Universidad de Mayores, de la Universidad de Valencia (N=652).  Instrumento: Cuestionario con datos de variables socio-demográficas, indicadores de participación social y la Escala Temporal de Satisfacción con la Vida. Se realizaron análisis descriptivos, prueba t,  MANOVA y análisis correlacionales. Resultados: Se encontraron diferencias en participación social a nivel global y en los diferentes tipos de participación social. Las mujeres participan más a nivel general y también  participan más en el cuidado informal mientras que  los hombres participan más en actividades deportivas. Las relaciones entre variables sugieren relaciones positivas entre participación social y satisfacción vital en general, aunque estas relaciones sólo difieren entre sexos en actividades deportivas y, para las mujeres la actividad física se relaciona significativamente con una mayor satisfacción y bienestar futuro. Conclusiones: Se observa un patrón estereotipado en relación al tipo y los lugares donde se llevan a cabo las actividades: los cuidados y el hogar son especialmente relevantes para las mujeres, mientras que la actividad física y los lugares públicos lo son más para los hombres.
Validez del Body Shape Questionnaire (BSQ) en mujeres Argentina
Authors: Nieri Liliana Poala
Published: April 2022

El presente estudio tuvo como objetivo validar el instrumento en población Argentina femenina Body Shape Questionnaire (BSQ), el mismo tiene como fin evaluar la insatisfacción corporal. Para ello selección una muestra de 605 mujeres pertenecientes a la Provincia de Buenos Aires con una media de edad 28.42 (DS=9.92).Los resultados arrojaron una puntuación total con una buena consistencia interna de .90, así como una estructura de 2 factores que explicaron el 51.98% de la varianza. Estos fueron: preocupación por el peso (α=.90) e insatisfacción corporal (α=.85). Con respecto a los índices de bondad de ajuste del modelo encontrado  (GFI=.85; CFI=.88; RMSEA=.07) demostraron la validez del cuestionario para medir con 21 ítems la insatisfacción corporal. Como conclusión  el cuestionario BSQ es útil para medir la insatisfacción corporal y la preocupación por el peso en mujeres de población Argentina.
Calidad de vida en personas con diabetes mellitus 2, obesidad o sobrepeso
Authors: Guadarrama Guadarrama Rosalinda , Álvarez López María Guadalupe , Arzate Hernández Giovanny , Veytia López Marcela
Published: April 2022

El objetivo fue comparar la calidad de vida (CV) en personas con diabetes mellitus tipo 2 (DM2) de acuerdo a la presencia de sobrepeso u obesidad, así como por gravedad de la enfermedad, la percepción de la calidad de vida (PCV) y el sexo. Para lo cual se contó con una muestra no probabilística de tipo intencional integrada por 95 pacientes que acudían a una clínica de control de la diabetes, los cuales respondieron el Cuestionario para la calidad de vida “Diabetes 39" validado para población mexicana. La aplicación se realizó de manera individual, previa explicación del proyecto de investigación, por lo cual la participación fue voluntaria. Para la obtención del índice de masa corporal (IMC), se revisaron los expedientes los cuales contenían las medidas antropométricas recientes. Los resultados permiten observar que no existen diferencias en la CV por IMC, pero no así por gravedad de la enfermedad, PCV y sexo. Lo que permitió concluir que la CV para estas personas no depende del IMC, pero la gravedad de la enfermedad, la PCV y el sexo si son factores que modifican la CV.
Factores de protección de duelo complicado en dolientes de primer grado: capacidad mindful y autocompasión
Authors: Alonso-Llácer Lorena , Lacomba-Trejo Laura , Pérez-Marín Marián
Published: April 2022

Marco teórico: la pérdida de un familiar de primer grado genera un gran impacto emocional y físico en la persona, pero la capacidad mindful y la autocompasión pueden amortiguarla. El objetivo general fue valorar la capacidad mindful, la autocompasión y la presencia de duelo complicado (DC) en dolientes de primer grado.

Método: 26 dolientes (84,60% mujeres), de 19 a 73 años (M=44,04; DT= 14,21) fueron evaluados mediante: Mindful Attention Awareness Scale, Escala de Autocompasión e Inventario de Duelo Complicado. Se realizaron análisis descriptivos, pruebas t, d de Cohen y correlaciones de Pearson.

Resultados: presentaron puntuaciones moderadas de capacidad mindful y autocompasión, pero un gran porcentaje (85,70%) mostraron DC. El DC fue mayor en mujeres, y se asoció con menor capacidad mindful y autocompasión. 

Conclusiones: es necesario conocer los factores de protección para desarrollar programas de intervención que incidan en ellos y favorezcan la salud física y mental de los dolientes.

Palabras clave: Dolientes, Duelo complicado, Atención al presente, Autocompasión, Factores protectores
Servicio de Atención Psicológica en el Hospital Marina Baixa (SAPMB) durante la Pandemia Covid-19
Authors: PARDOS GASCÓN ESTELA MARIA , Andreu Ruiz José Vicente , Beltrán Navarro Álvaro , Almagro García Paloma , Muñoz Muñoz Diana , Cerezo Guaita Lorena , Soler Fernández Nicolás , Gómez Calmaestra Nicolás , Rodríguez Vacas Mª Victoria , Antón Rupérez Beatriz
Published: April 2022

El presente trabajo pretende desarrollar la puesta en marcha de un servicio de atención psicológica en el Hospital Marina Baixa (Villajoyosa, Alicante), así como detallar la intervención realizada con diferentes tipos de afectados, tras el comienzo de la pandemia por COVID-19. La fundamentación de la creación del servicio fue la importancia dada a la prevención primaria, resaltar el cuidado emocional de las personas y ofrecer intervención en crisis. Se propusieron diferentes objetivos como prestar apoyo psicológico al personal interviniente en primera línea, a personas ingresadas afectadas por el virus y a sus familiares. Con el personal sanitario se llevaron a cabo intervenciones grupales de regulación emocional basadas en Mindfulness e intervenciones telefónicas/presenciales con aquellos que lo requirieron. Respecto a los pacientes, la intervención consistió en asistencia psicológica de manera presencial y telefónica a pacientes positivos ingresados y los familiares de éstos. Se registraron el número de usuarios atendidos en las diferentes formas de intervención, que se tuvo que ir adaptando a las necesidades detectadas en la población atendida y a la evolución de la pandemia. Los resultados muestran que, mediante la creación de este servicio, se cumplieron los objetivos marcados.
PtSe2 and Black Phosphorus employed for sensitivity improvement of Surface Plasmon Resonance Sensor
Authors: Karki Bhishma , Ansari Gufranullah , Uniyal Arun , Srivast Vivek
Published: April 2022

The analysis aims to enhance the sensitivity of the surface plasmon resonance-based biosensor. The proposed sensor consists of a single layer of Ag metal, black phosphorus (BP), and PtSe2. The thickness of the Ag metal is considered as 45 nm. The study has been carried using attenuated total internal reflection (ATR). The refractive index of the sensor changes when analyte or biomolecules comes in contact with the sensing layer. The thickness of the BP layer has been taken as 0.34nm. The maximum sensitivity of the sensor is achieved for one layer of PtSe2 and two layers of BP. The calculated performance parameters, sensitivity, figure of merit, and detection accuracy is 275.2\(^\circ /\text{R}\text{I}\text{U}\), 43.1 RIU−1, and 0.16 deg−1, respectively. The sensitivity of the proposed sensor is 1.38 times the conventional sensor.
Real-time phase contrast MRI versus conventional phase contrast MRI at different spatial resolutions and velocity encodings
Authors: LIU Pan , FALL Sidy , AHIATSI Maureen , BALEDENT Olivier
Published: April 2022

BackgroundConventional cine phase-contrast MRI (Conv-PC) is the gold standard for blood flow measurements but can only provide flow measurements for an averaged heartbeat cycle (using cardiac gating). In contrast to Conv-PC, phase-contrast echo-planar MRI (EPI-PC) can be used to quantify the blood flow rate in real-time – giving the technique great potential for clinical and research applications. The objectives of the present in vitro study were to compare the accuracy of EPI-PC and Conv-PC and to assess the influence of pixel size and velocity encoding on flow measurements obtained with the two sequences.MethodsFlow quantification was assessed using a pulsatile flow phantom. The flow rate curves were extracted with in-house post-processing software, and the flow curves from EPI-PC were reconstructed to give an average pulse cycle with 32 sampling points with the same waveform as that obtained with Conv-PC. Firstly, the accuracy of the EPI-PC was checked by comparing it with the flow rate in the calibrated phantom and the pulsation index from Conv-PC. Secondly, flow data from the two sequences were compared quantitatively as a function of the pixel size and the velocity encoding.ResultsThe mean percentage difference between the EPI-PC flow rate and calibrated phantom flow rate was -2.9 %, which was within the confidence interval. The pulsatility indices for EPI-PC and Conv-PC were respectively 0.64 and 0.59. In order to keep the flow rate measurement error within 10%, the ROI in Conv-PC had to contain at least 13 pixels, while the ROI in EPI-PC had to contain at least 9 pixels. Furthermore, Conv-PC had a higher velocity-to-noise ratio and could use a higher velocity encoding than EPI-PC (20cm/s and 15cm/s, respectively).ConclusionsThe result of an in vitro study confirmed the accuracy of EPI-PC. Furthermore, EPI-PC was found to be less sensitive than Conv-PC at a low spatial resolution but was more sensitive than Conv-PC to velocity encoding.
Electronic and optical properties of CdxMg1-xO alloys, TB- mBJ calculations
Authors: Djaili Salim , Lagoun Brahim , Smain Taher , Amour Ali , Soleh Kouider , Hachi Mohamed
Published: April 2022

The magnesium and cadmium oxides (MgO, CdO) are widely used in the optoelectronic technology, for that raison it very interest subject of researches.
In this work, the structural, elastic, electronic and optical properties of rock-salt Cd x Mg 1-x O were investigated using both exchange correlations LDA and GGA-WC. The calculations were implemented using Full-Potential Linearized Augmented Plane Wave (FP-LAPW) method in the framework of the Density Functional Theory (DFT). For the electronic and optical properties, the calculations were performed using the Tran-Blaha-modified Beck Johnson potential (TB-mBJ).
The lattice parameter have been reported for different cadmium concentrations x in the rocksalt structure, the calculated lattice parameter to be transmitted quasi-linearly from 4.257 A to 4.43 A for rock-salts MgO and rock-salts CdO respectively, For rs MgO and rs CdO, the obtained results are very acceptable with experimental results existing in the literature. The deviations between our results and experimental data is less than 1%.
The estimated bandgap values to be 7.39eV for rs-MgO (rock salt) and 1.81eV for rs-CdO, the results deviate by less than 5% from experimental results. The energy bandgap (Eg) for x = 0, 0.25, 0.50, 0.75, and x = 1 varied quasi-linearly. Moreover, the optical parameters of Cd x Mg 1-x O such as the dielectric function, the reflectivity, the refractive index, and the electron-loss-energy function have also been studied and discussed. Our findings results for rs MgO and rs CdO are also in good agreement with the experimental data, our results prove that the plasma frequency varied non-laniary from 7.33eV for rs MgO to 3.03eV for rs CdO.
Diverse breast adipose stromal cell biology in women at high risk for developing breast cancer
Authors: Taskindoust Mahsa , Stukes Bryanna , Nelson Valery , Charles Matthew , Santiago Lindsay , Xie Tingjun , Marks Jeffrey , Hwang E. Shelley , Hollenbeck Scott T. , Bachelder Robin E.
Published: April 2022

Purpose: Adipose tissue constitutes a significant volume of the breast. However its influence on breast cancer initiation remains poorly understood. Breast adipose stromal cells (breast ASCs), essential progenitors of breast fat tissue, are abundant in breast adipose tissue. We studied the biology of primary human bASCs and their contribution to the tumor microenvironment.Methods: We generated a bASC cell repository from women undergoing prophylactic or therapeutic mastectomies (n=6 breast cancer patients; n=2 high risk patients). bASCs were isolated from the stromal vascular fraction of breast adipose tissue. Senescence was measured in bASCs using the senescence-associated beta-galactosidase detection kit. Senescence-associated-cytokines and chemokines in conditioned media collected from bASCs were measured by ELISA. The ability of bASCs to support cytokine signaling was determined by immunoblotting. Adipogenic potential of bASCs was determined by AdipoRed staining.Results: bASCs from 63% (5/8) of women in our cohort scored positive for senescence, with only some secreting senescence-associated cytokines (IL-6; TGF-beta) and chemokines (IL-8). Only in select cases was bASC secretion of cytokine associated with their ability to support cytokine-specific signaling pathways (e.g. TGFb/Smad2 signaling). bASCs from 38% (3/8) of these women exhibited an adipogenesis defect, and 2/3 (67%) also scored positive for senescence.Conclusion: bASC biology shows notable biologic variability in women undergoing prophylactic or therapeutic mastectomies, with some exhibiting a senescent phenotype, some exhibiting an adipogenesis defect, and some supporting TGFb or IL-6 signaling. Our results establish an important foundation for larger studies examining the impact of aberrant bASC biologies on breast cancer risk.
A nomogram predicting overall survival for metastatic pancreatic cancer: SEER database analysis
Authors: Liu Kun , Chen Jiaoshun , Zhang Haoxiang , Bai Jianwei , Chen Taoyu , Cheng Shibo , Wu Heshui , Yin Tao
Published: April 2022

Background: This study's motive was to find out the determinants of average survival for sufferers with metastatic pancreatic cancer (PC) and formulate a nomogram to evaluate overall survival (OS).Methods: A whole of 10165 sufferers with metastatic PC identified from 2010 to 2015 were recruited from the Surveillance, Epidemiology, and End Results (SEER) application. All sufferers were randomly assigned to a training set (n=7117) and an internal validation set (n=3048). A nomogram was built derived from univariate and multivariate Cox evaluation to evaluate an individual patient's 6-, 12- and 18-month OS. The nomogram's overall performance used to be assessed via concordance index (C-index), receiver operating characteristic (ROC) curves, and calibration plots.Results: A whole of 10165 sufferers with metastatic PC identified from 2010 to 2015 had been included. Our analysis revealed that age, race, grade, N stage, bone metastasis, brain metastasis, liver metastasis, lung metastasis, surgery, and chemotherapy were identified as independent predictors for overall survival. The C-index of training set was 0.681 (95%CI:0.673-0.689) and validation set was 0.689 (95%CI:0.677-0.701). The calibration curves validated that the nomogram estimated 6-, 12- and 18-month OS precisely. Kaplan-Meier curves confirmed sizable variation in OS amongst the stratified low-, and high-risk groups (P<0.0001).Conclusions: The nomogram efficiently forecasts OS in sufferers with metastatic PC. This predictive model may assist clinicians in risk stratification, prognosis predictions, and facilitating personalized treatment.
Barriers in Implementation of Circular Economy Approach with the Consumption of Oilfield Produced Water
Authors: Sarma Sumita , Attaran Sharmin , Attaran Mohsen
Published: April 2022

A circular economy approach within wastewater consumption for agriculture has gained relevance in recent years. Extreme climate conditions (e.g., megadrought in California) have resulted in severe water shortages, yet there seems to be a reluctance to accept alternative water sources. Despite the numerous local initiatives towards oilfield water reuse, barriers remain to its implementation in practice. This study identifies the barriers towards widespread adoption of Oilfield Produced Water (OPW) for crop irrigation. Semi-structured interviews were conducted with five major stakeholder groups of the OPW: oil and gas managers/ business owners, farmers, entrepreneurs, water district managers, and water board personnel. This study used qualitative data analysis to identify factors influencing the beneficial uses and barriers to reusing OPW. The findings highlighted three macro-categories: water shortages, costs of treatment Vs. the expected benefits, and public perceptions vs. scientific studies based on thematic relevance and coherence. The interviews revealed the need for a tighter collaboration among the various stakeholder groups in this ecosystem that involves public-private partnerships and shared governance in managing the environment—addressing these barriers aids the development of a circular economy for wastewater.
Study on the Influence Factors and Mechanism of Chromium Removal by Sulfide Nano-zero Valent Iron
Authors: Li Yajun , Zhang Yongxiang , Lin Yuhui , Yang Wenjing , Du Wei , Zhao Chonghui
Published: April 2022

In this study, two-step methods were used to prepare sulfide nano-zero valent iron and the morphology, elemental composition, surface charge, crystal structure and elemental valence were characterised. The influence factors (S/Fe ratio, initial pH and initial concentration of Cr(VI)) and the mechanism of Cr(VI) removal was determined. The results revealed that the sulphide modification could increase the removal rate of chromium. The maximum removal rate of chromium was 81 mg/g, achieved at an S/Fe ratio of 0.1. The Cr(VI) removal process by S-nZVI0.1 is a multistep process, starting with strong adsorption to the surface of the particles by adsorption, followed by reduction of Cr(VI) to Cr(III), and finally fixing the contaminants on the S-nZVI0.1 surface by co-precipitation. This study has great significance for preparing a remediation material that could be efficiently used for repairing of Cr(VI) contaminated sites.
Associations between urine cobalt and prevalence of kidney stones in American s aged ≥ 20 years old
Authors: Wang Jia , Xiao Yunfei , Yin Shan , Bai Yunjin , Wang Jiahao , Cui Jianwei
Published: April 2022

To determine whether urine cobalt is associated with the prevalence of kidney stones. We conducted a cross-sectional study of participants (≥ 20 years) involved in the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018. Urine cobalt level was divided into four groups: 0.02–0.22, 0.22–0.36, 0.36–0.58 and 0.58–37.40 ug/L. The independent correlation between urine cobalt and prevalence of kidney stones was determined by logistic regression analyses. Totally 10,744 participants aged over 20 years without pregnancy were eligible. Among them, 1,041 participants reported as ever having developed kidney stones. Patients with kidney stones developed significantly higher urine cobalt than the non-stone participants. The kidney stone patients were more likely to have smoking ≥ 100 cigarettes in life, hypertension, diabetes, cancer, and heavy activity. Multivariate logistic regression indicated a significantly positive relationship between urine cobalt level and occurrence of kidney stones (OR 1.059, 95%CI 1.018–1.102). Moreover, the outcome remained unchanged after some sophisticated factors were adjusted (OR 1.048, 95%CI 1.005–1.093), and the incidence of kidney stones rose with the increasing urine cobalt level [OR (95%CI) = 0.22–0.36 ug/L: 1.166 (0.955–1.422); 0.36–0.58 ug/L: 1.348 (1.108–1.640); 0.58–37.40 ug/L: 1.683 (1.382–2.044)]. Higher urine cobalt concentration is significantly related to an increased risk of kidney stones. However, more high-quality prospective studies are needed to elucidate the causal correlation between cobalt level and kidney stones.
Assessment of nutritive compositions of a novel wrinkled-leaf sesame mutant JQA: A new leafy vegetable suitable for eating
Authors: Liu Hongyan , Zhou Fang , Zhou Ting , Yang Yuanxiao , Zhao Yingzhong
Published: April 2022

Sesame leaves represent a new edible vegetable. However, data regarding the nutritional composition of the leaves, especially their phytonutrient composition, are scarce. In this study, the nutrient content of a new wrinkled-leaf sesame mutant JQA were determined. Chromatographic techniques with UV-Vis and mass detection were used to analyze the vitamin and flavonoid components. Inductively coupled plasma-atomic emission spectrometry was used to characterize the mineral content of the leaves, and standard techniques were used to determine the corresponding indicators. We found that sesame leaves had a low crude fat (5.33%), saturated acid (24.772%), unsaturated acid (32.012%), and crude fiber (36.16%) content, and a high content of water (86.50%), total flavones (65.672 mg/g), K (16.118 mg/g), vitamin C (1.695 mg/g), vitamin A (0.97 mg/g), vitamin D (1.33 mg/g), and vitamin B2 (14.4 mg/g). The sesame leaves were high in vitamins, calcium, and potassium compared to other common green leafy vegetables. The fresh leaves had a mean total flavone content of 65.672 mg/g, mainly composed of glycosylated quercetin and kaempferol derivatives. Sesame leaves can be eaten fresh or can be preserved in a dry state for more than one year. The nutritional composition was generally stable during storage. These results suggested that the wrinkled sesame leaves are a rich source of nutrients and therefore have potential use as an edible vegetable.
Investigation of dirigent like domains from bacterial genomes
Authors: Bardin Merlin , Rousselot-Pailley Pierre , Tron Thierry , Robert Viviane
Published: April 2022

BACKGROUND: Dirigent proteins (DIRs) have been named after plant proteins capable to direct the stereoselectivity in the coupling of radicals from various metabolites. Recently, evidence that DIR proteins occurred far more abundantly than previously thought (i.e., beyond plant kingdom) have been obtained.RESULTS: Analyzes of structural and functional genomic data led to the identification of the Pfam PF03018 domain as characteristic of DIR proteins. This domain has been further identified in the sequence of bacterial proteins therefore named as DIR-like (DIRL). The objective of this study was to perform a thorough bioinformatic analysis on these DIRLs to highlight any information leading to the selection of candidate bacteria for further cloning, purification, and characterization of bacterial DIRs. CONCLUSIONS: From studies of primary structures, predictions of their secondary and tertiary structures, prediction of DIRL signals sequences, analysis of their gene organization and potential regulation, a list of primary bacterial candidates is proposed.
Systematic treatment of giant gastroduodenal anastomotic leakage: a case report
Authors: Yang Rui , Wang Yinchun , Yang Yuyi , Yang Qingqiang
Published: April 2022

Background: Gastroduodenal anastomotic leakage is one of the most dreadful complications of gastrectomy and poses a great threat for treatment. However, there has been no effective treatment for it up to now. We report a case, a patient with huge gastroduodenal anastomotic leakage, was eventually recovered after conservative treatment up front and later resolution of anastomotic obstruction through gastrojejunostomy and jejunostomy.Methods and results: A 50-year-old man underwent a distal gastrectomy for a giant penetrating ulcer in the lesser curvature of the gastric sinus. Digestive reconstruction was completed by the Billroth I method. But an anastomotic leakage occurred on postoperative day 9 and a high output of duodenal juice was observed, and the following gastroscopy suggested that there was a large breach in the gastroduodenal anastomosis. Because of the patency of the drainage tube and the limitations of the patient's condition, conservative treatment was advocated and a nasojejunal tube was placed under the gastroscope for enteral nutrition. Unexpectedly, during subsequent treatment, persistent hypothermia associated with rheumatoid arthritis, drainage-associated transverse colon leakage and anastomotic stenosis occurred. Eventually, after taking the gastrojejunostomy and jejunostomy and gradually withdrawing and flushing the drainage tube, the patient was able to achieve a tube-free state and eat in the normal way.Conclusion: The course of the patient’s treatment was continuous and systematic. In this case, we found that conservative treatment was feasible for giant gastroduodenal anastomotic leakage in the presence of patent drainage and limited physical signs. And for secondary anastomotic stenosis, gastrojejunostomy can effectively relieve the obstruction.
Understanding the needs and priorities of people living with persistent pain and long-term musculoskeletal conditions during the Covid-19 pandemic.
Authors: Davis Sally Fowler , Humphreys Helen , Maden-Wilkinson Tom , Withers Sarah , Lowe Anna , Copeland Robert J
Published: April 2022

Background: Critiques of public involvement (PI) are associated with failing to be inclusive of under-represented groups and this leads to research that fails to include a diversity of perspectives. Aim: The aim of this PI project was to understand the experiences and priorities of people from three seldom heard groups whose musculoskeletal pain may have been exacerbated or treatment delayed due to COVID-19. Engaging representatives to report diverse experiences was important, given the goal of developing further research into personalised and integrated care and addressing population health concerns about access and self-management for people with musculoskeletal pain.Methods: The project was approved via Sheffield Hallam University Ethics but was exempt from further HRA approval. A literature review was conducted followed by informal individual and group discussions involving professionals and people with lived experience of fibromyalgia pain, those waiting for elective surgery and experts associated with the care home sector. Findings from the literature review were combined with the insights from the public involvement. Together, these formed narratives that highlighted the challenges associated with persistent pain and informed the creation of consensus statements on the priorities for service improvement and future research. The consensus statements were shared and refined with input from an expert steering group.Results: The narratives describe pain as a uniformly difficult experience to share with professionals; it is described as exhausting, frustrating, and socially limiting. Pain leads to exclusion from routine daily activities and often resigns people to feeling and being unwell. In all cases there are concerns about accessing and improving services and critical issues associated with optimising physical activity, functional wellbeing and managing polypharmacy. Exercise and/or mobilisation are important and commonly used self-management strategies but opportunity and advice about safe methods are variable. Services should focus on personalised care including self-management support and medication management so that people’s views and needs are heard and validated by health professionals. Conclusions: More research is needed to prioritise the most effective pain management strategies and public involvement is important to shape the most relevant research questions. Health and care systems evaluation is needed to address the scale of the population health need. The pandemic appears to have highlighted pre-existing shortcomings in holistic pain management.
Atrial approach in mitral valve surgery: A propensity analysis of differences in the incidence of clinically relevant adverse effects
Authors: Obando Carlos E , Garzón Javier , Ramirez Lina , Castillo Andrea , Guerrero Albert , Chalela Tomas , Sandoval Diana C , Giraldo-Grueso Manuel , Sandoval Nestor F , Camacho Jaime , Umaña Juan Pablo
Published: April 2022

Background: The lack of evidence on postoperative outcomes using mitral valve approaches leaves the choice to the surgeon’s preference, based on individual experience, speed, ease, and quality of exposure.Methods: The present study analysed patients undergoing mitral valve surgery using a superior transseptal approach or a left-atrial approach between 2006 and 2018. We included first-time elective mitral valve procedures, isolated, or combined, without a history of rhythm disturbances. We used propensity score matching based on 26 perioperative variables. The primary endpoint was the association between the superior transeptal approach and clinically significant adverse outcomes, including arrhythmias, need for a permanent pacemaker, cerebrovascular events, and mortality.Results: A total of 652 patients met the inclusion criteria; 391 received the left atrial approach, and 261 received the superior transseptal approach. After matching, 96 patients were compared with 69 patients, respectively. The distribution of the preoperative and perioperative variables was similar. There was no difference in the incidence of supraventricular tachyarrhythmias. The incidence of nodal rhythm (p= 0.008) and length of stay in intensive care (p= 0.04) were higher in the superior transseptal group, but the need for permanent pacemaker implantation was the same. Likewise, there was no difference in the need for anticoagulation due to arrhythmia, the incidence of cerebrovascular events or mortality in the postoperative period or in the long-term follow-up.Conclusion: We did not find an association with permanent heart rhythm disorders or any other significant adverse clinical outcome. Therefore, the superior transeptal approach is useful and safe for mitral valve exposure.
Genome-wide Association Study of Thoracic Aortic Aneurysm and Dissection in the Million Veteran Program
Authors: Klarin Derek , Devineni Poornima , Sendamarai Anoop , Angueira Anthony , Graham Sarah , Shen Ying , Levin Michael , Pirruccello James , Surakka Ida , Karnam Purushotham , Roychowdhury Tanmoy , Li Yanming , Wang Minxian , Aragam Krishna , Paruchuri Kaavya , Shakt Gabrielle , Tsao Noah , Judy Renae , Vy Ha My , Verma Shefali , Rader Daniel , Do Ron , Bavaria Joseph , Nadkarni Girish , Ritchie Marylyn , Guo Dongchuan , Ellinor Patrick , LeMaire Scott , Milewicz Dianna , Willer Cristen , Natarajan Pradeep , Tsao Phil , Pyarajan Saiju , Damrauer Scott
Published: April 2022

Current understanding of the genetic contribution to thoracic aortic aneurysms and dissections (TAAD) has largely been informed through studies focusing on rare, Mendelian forms of disease. In the current analysis we performed the largest genome-wide association study (GWAS) of TAAD to date, testing ~25 million DNA sequence variants in 8,626 participants with (7,050 European, 1,266 African, and 310 Hispanic ancestry individuals) and 453,043 participants without TAAD in the Million Veteran Program. The results were replicated in an independent sample of 4,459 individuals with and 512,463 without TAAD from 6 cohorts. We identified 21 TAAD loci, 17 of which have not been previously reported. We leverage phenome-wide scanning and causal inference methods to provide evidence that TAAD is a non-atherosclerotic aortic disorder distinct form other forms of vascular disease; we subsequently use Bayesian techniques and single cell/nucleus RNA sequencing data to identify causal risk genes and cell types. Finally, we generate a TAAD polygenic risk score and demonstrate that those at the top 5% of polygenic risk are over 4-fold more likely to experience an incident, fatal TAAD event. Our results demonstrate that the genetic architecture of TAAD mirrors that of other complex traits and is not solely inherited through protein altering variants of large effect size. These data provide new mechanistic insights into TAAD risk and improve our understanding of thoracic aortic disease.
The nurse: relationship between leadership style, values and Quality of Work Life
Authors: Rached Chennyfer Dobbins Abi , Sousa Gabriella de Castro , Borges Flávio Adriano , Carloni Pablo Ramon Rodrigues Freitas Ramos , Domercant Herline , Siqueira Bianca Batista
Published: April 2022

Background: Leadership has been widely studied over the years due to its importance to organizations. The leader must be able to direct their team to reach the objectives and goals established in the organization, creating a work environment capable of providing this. Value-oriented leaders, teams, organizations, and communities are the most successful when they are able to engage workers in such a way that there are gains in retention rates and reduced absenteeism. Quality of Work Life is something that goes beyond labour laws. It is a dynamic that involves physical, technological, social, and psychological factors, which change and influence the organizational climate, reflecting on the worker's well-being and, consequently, on their productive capacity. Objective: To analyse the relationship between leadership styles, personal values ​​of nursing leaders and the Quality of Work Life of nurses who attend the Graduate Program in Nursing Management (PPGEn). Methods: This is a quantitative, cross-sectional study. Data were collected using the standardized instrument Quality of Working Life Questionnaire (QWLQ-bref), and an exploratory-descriptive analysis was performed. Results: Of the 123 nurses interviewed, 64.22% rated the Quality of Work Life as satisfactory and 31.7% as very satisfactory. Through these data, the relationship between the task leadership style and professional satisfaction in the nurse's quality of life was perceived. Conclusion: The results do not point to a relationship between the managerial style of the nurse leader and the perception of Quality of Work Life. However, it is noteworthy that the Quality of Work Life describes values ​​that go beyond the human. Conclusion: The results of this study did not indicate a correlation between leadership styles, personal values ​​and the perception of Quality of Work Life, however, conclusions can be made from the highest and lowest scores presented. Everyone in a leadership role should be aware of the values ​​they hold, their strengths, and the areas they can improve as they grow as a leader. The importance of a positive organizational climate so that the established goals are achieved is clear, and, in this sense, valuing the human factor will make the achievement of goals more feasible.
Impact of essential amino acid intake, resistance exercise, and aging on the concentration of Achilles peritendinous amino acids and procollagen I⍺1 in humans
Authors: Campbell Nathan W.C. , Patel Shivam H. , Ferrandi Peter , Couture Samantha , Farino Dominick O. , Stout Julianne , Sabbaghi Arman , Carroll Chad C.
Published: April 2022

Several recent studies have shown that consuming amino acid-rich compounds improves tendon collagen content and biomechanical properties. Yet, it is not clear if the consumption of amino acids alters local (peritendinous) amino acid concentrations. If aging or exercise influence local amino acid concentrations in conjunction with an amino acid bolus is also not known. We conducted two studies. In Study 1, young women (n=7, 25+/-2 yrs.) completed two identical resistance training sessions with either essential amino acid (EAA) or placebo consumption. In Study 2, an EAA bolus identical to Study 1 was given to younger (n=7; 27+/-1 yr.) and older adults (n=6; 68+/-2 yrs.). Microdialysis was used to determine Achilles peritendinous amino acid and pro-collagen I⍺1 (a marker of collagen synthesis) concentrations. In Study 1, amino acid consumption increased peritendinous concentrations of all EAA except histidine (p<0.05). In Study 2, the peritendinous concentration of EAAs except for methionine, histidine, and lysine (p>0.05) increased with time (p<0.05). Further, the concentrations of most measured amino acids were greater in older adults (p<0.05). Pro-collagen I⍺1 concentration (p>0.05) was unaffected by exercise, EAA, or aging (p>0.05). Our findings demonstrate that: 1) when not combined with exercise, an oral EAA bolus leads to only modest increases in Achilles peritendinous amino acid concentrations, 2) when combined with resistance exercise, EAA consumption resulted in greater peritendinous amino acid concentrations compared to no exercise, 3) the basal concentrations of most amino acids were greater in older adults, and 4) neither the EAA bolus nor exercise altered peritendinous pro-collagen concentrations.