bluuebunny/crossref_metadata_2025 huggingface dataset:
Complementary Use of Bioluminescence Imaging and Contrast-Enhanced Micro—Computed Tomography in an Orthotopic Brain Tumor Model
Authors: Yahyanejad Sanaz , Granton Patrick V. , Lieuwes Natasja G. , Gilmour Lesley , Dubois Ludwig , Theys Jan , Chalmers Anthony J. , Verhaegen Frank , Vooijs Marc
Published: March 2018

Small animal models are crucial to link molecular discoveries and implementation of clinically relevant therapeutics in oncology. Using these models requires noninvasive imaging techniques to monitor disease progression and therapy response. Micro–computed tomography (CT) is less studied for the in vivo monitoring of murine intracranial tumors and traditionally suffers from poor soft tissue contrast, whereas bioluminescence imaging (BLI) is known for its sensitivity but is not frequently employed for quantifying tumor volume. A widely used orthotopic glioblastoma multiforme (GBM) tumor model was applied in nude mice, and tumor growth was evaluated by BLI and contrast-enhanced microCT imaging. A strong correlation was observed between CT volume and BLI-integrated intensity (Pearson coefficient ( r) = .85, p = .0002). Repeated contouring of contrast-enhanced microCT-delineated tumor volumes achieved an intraobserver average pairwise overlap ratio of 0.84 and an average tumor volume coefficient of variance of 0.11. MicroCT-delineated tumor size was found to correlate with tumor size obtained via histologic analysis (Pearson coefficient ( r) = .88, p = .005). We conclude that BLI intensity can be used to derive tumor volume but that the use of both contrast-enhanced microCT and BLI provides complementary tumor growth information, which is particularly useful for modern small animal irradiation devices that make use of microCT and BLI for treatment planning, targeting, and monitoring.
Optimization of Dual-Labeled Antibodies for Targeted Intraoperative Imaging of Tumors
Authors: Rijpkema Mark , Bos Desirée L. , Cornelissen Alex S. , Franssen Gerben M. , Goldenberg David M. , Oyen Wim J. , Boerman Otto C.
Published: March 2018

For intraoperative imaging, antibodies labeled with both a radionuclide and a fluorophore may be used to tag the tumor lesion with a radiolabel and a fluorescent signal at high tumor to background ratios. However, labeling antibodies with fluorescent moieties may affect the in vivo behavior of the antibody depending on the dye to antibody substitution ratio. To investigate the optimal substitution ratio for use in dual-modality image-guided surgery, we conjugated three different antibodies, MN-14 (anti-CEACAM5), girentuximab (anti-CAIX), and cetuximab (anti-EGFR), with both diethylene triamine pentaacetic acid (DTPA, for labeling with 111In) and IRdye 800CW at dye to antibody ratios of 0, 1, 1.5, 2, and 3 and assessed in vivo behavior. Biodistribution studies showed that at high dye to antibody ratios, liver uptake of the dual-labeled antibodies increased, whereas tumor uptake decreased. Conversely, very low ratios may not be optimal either because in that case, only a few antibody molecules will be dual-labeled (i.e., contain both a DTPA and an IRDye 800CW moiety), which may complicate interpretation of dual-modality data. The present study shows that, provided that the chelator to antibody ratio is high enough, a dye to antibody ratio in the range of 1 to 1.5 is optimal for antibody-targeted dual-modality imaging applications. However, the optimal configuration is antibody dependent and should be determined for each dual-labeled antibody individually.
[11C]Carfentanil Binds Preferentially to μ-Opioid Receptor Subtype 1 Compared to Subtype 2
Authors: Eriksson Olof , Antoni Gunnar
Published: March 2018

The positron emission tomography (PET) ligand [11C]carfentanil is a selective agonist for μ-opioid receptors and has been used for studying μ-opioid receptors in the human brain. However, it is unknown if [11C]carfentanil binding differentiates between subtype receptors μ1 and μ2. In this study, we investigated whether μ1 and μ2 can be studied separately through receptor subtype–selective inhibition of [11C]carfentanil by pharmacologic intervention. [11C]Carfentanil binding characteristics on rat brain sections were assessed either alone or in the presence of the μ-receptor inhibitor cyprodime or the μ1-specific inhibitor naloxonazine. [11C]Carfentanil binding in the living rat brain was similarly studied by small animal PET/computed tomography during baseline conditions or following displacement by cyprodime or naloxonazine. Autoradiography binding studies on rat brain sections demonstrated that [11C]carfentanil has higher affinity and binding potential for μ1 than for μ2. [11C]Carfentanil binding to μ2 in vivo could not be detected following specific blocking of μ1, as predicted from the low binding potential for μ2 as measured in vitro. [11C]Carfentanil binding is preferential for μ1 compared to μ2 in vitro and in vivo. Clinical studies employing [11C]carfentanil are therefore likely biased to measure μ1 rather than μ2.
Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure
Authors: Carter Sophie , Miard Stéphanie , Caron Alexandre , Sallé-Lefort Sandrine , St-Pierre Philippe , Anhê Fernando Forato , Lavoie-Charland Emilie , Blais-Lecours Pascale , Drolet Marie-Claude , Lefebvre Julie S. , Lacombe Julie , Deshaies Yves , Couet Jacques , Laplante Mathieu , Ferron Mathieu , Bossé Yohan , Marette André , Richard Denis , Marsolais David , Picard Frédéric
Published: March 2018

The current demographic shift toward an aging population has led to a robust increase in the prevalence of age-associated metabolic disorders. Recent studies have demonstrated that the etiology of obesity-related insulin resistance that develops with aging differs from that induced by high-calorie diets. Whereas the role of adaptive immunity in changes in energy metabolism driven by nutritional challenges has recently gained attention, its impact on aging remains mostly unknown. Here we found that the number of follicular B2 lymphocytes and expression of the B-cell-specific transcriptional coactivator OcaB increase with age in spleen and in intra-abdominal epididymal white adipose tissue (eWAT), concomitantly with higher circulating levels of IgG and impaired glucose homeostasis. Reduction of B-cell maturation and Ig production—especially that of IgG2c—by ablation of OcaB prevented age-induced glucose intolerance and insulin resistance and promoted energy expenditure by stimulating fatty acid utilization in eWAT and brown adipose tissue. Transfer of wild-type bone marrow in OcaB−/− mice replenished the eWAT B2-cell population and IgG levels, which diminished glucose tolerance, insulin sensitivity, and energy expenditure while increasing body weight gain in aged mice. Thus these findings demonstrate that upon aging, modifications in B-cell-driven adaptive immunity contribute to glucose intolerance and fat accretion.
A Multicenter Randomized Double-blind Controlled Clinical Trial of Fiber Post Cementation Strategies
Authors: Bergoli CD , Brondani LP , Wandscher VF , Pereira GKR , Cenci MS , Pereira-Cenci T , Valandro LF
Published: March 2018

Objectives:

The aim of this prospective randomized multicenter clinical trial was to evaluate the survival rate of glass fiber–reinforced posts cemented with self-adhesive or regular resin cements.

Methods:

The sample was comprised of 152 teeth randomized within two centers and in accordance with the adhesive strategies for RelyX U100/U200 (3M ESPE) or Single Bond and RelyX ARC (3M ESPE). The cementation procedures were standardized and performed by previously trained operators. The primary outcome evaluated was post debonding. A trained evaluator, one for each center, assessed all subjects at intervals of 12 months for up to 6 years. Statistical analysis was performed using the Kaplan-Meier method.

Results:

There was no statistically significant difference in survival rates between the two strategies assessed (p=0.991), with a 92.7% survival rate for the self-adhesive cement and 93.8% for the regular cement.

Conclusion:

Both the self-adhesive and the regular resin cements are good alternatives for glass fiber post cementation.
Videojuegos y habilidades del pensamiento / Videogames and thinking skills
Authors: Rivera Arteaga Eduardo , Torres Cosío Verónica
Published: March 2018

El presente documento es una revisión de artículos sobre los videojuegos y las habilidades del pensamiento que se trabajan cuando se practica este pasatiempo. Se revisó el trabajo de diferentes autores que se han adentrado en este tema. También se mencionaron las habilidades involucradas y se dio una breve descripción de las mismas. El punto crítico llegó con los trabajos de James Paul Gee, quien compara las habilidades del pensamiento y, por tanto, de aprendizaje, adquiridas y desarrolladas con los videojuegos y en la escuela, dejando una tentadora reflexión: ¿qué cambios se necesitan hacer para que los alumnos aprendan en la escuela al igual que como aprenden con los videojuegos?
ISSUES AND CHALLENGES OF UPDATED LIBRARY FACILITIES IN DIGITAL ERA
Authors: Jayalakshmi C.
Published: March 2018

Libraries will need to enhance and upgrade nowadays since the world steps into the Digital systems.The major issue is that of the technical architecture that underlies any library which encompass both electronic and paper materials.Infact, Digital Libraries are also the digital face of traditional libraries that include both digital collections and traditional fixed media collections.It will also include digital materials that exist outside the physical and administrative bounds of anyone.  It includes all the process and services that are taken to the backbone and nervous systems of Libraries. This paper identifies various additional jobs of professional librarians those are well versed with science and technology applications.The government policy based challenge and need Library facilities in Digital Era are presented. The copyright issue plays an important role as well as the challenges are the complying with the copyright and intellectual property of right issues. Also the executive summary of impact of on Library Information Centre role on country population enrolled   under digitization process through aadhar card.
RANCANG BANGUN ALAT PENGERING DENGAN SISTEM PENGERINGAN GABUNGAN PERPINDAHAN PANAS TIDAK LANGSUNG DAN VAKUM
Authors: Rukmana Jaka , Bindar Yazid
Published: March 2018

Tujuan umum dari penelitian ini adalah untuk pencapaian ketahanan pangan Indonesia melalui pembangunan industri hilir berbahan baku tepung nangka. Tujuan khususnya adalah untuk melakukan kajian mengenai produksi tepung nangka menggunakan alat pengering dengan sistem pengering gabungan antara perpindahan panas tidak langsung dan kondisi vakum. Penelitian ini terbagi kedalam 3 tahap. Tahap pertama adalah merancang alat pengering, uji performa alat pengering, dan penentuan kondisi optimum untuk produksi tepung nangka.  Tahap kedua adalah pengujian umur simpan tepung nangka. Tahap ketiga adalah uji kegunaan tepung nangka yang dihasilkan. Hasil penelitian tahap pertama menunjukan bahwa alat pengering hasil perancangan memiliki performa yang baik. Hal ini ditunjukan dengan nilai humiditi dari ruang pengering sebesar 0,0186 kg H2O / kg udara kering dan tekanan yang stabil selama proses pengeringan yaitu sebesar -61,5 cmHg.
IDENTIFICATION AND INHIBITION OF BIOACTIVE COMPOUNDS FROM NUTMEG ( Myristica fragrans Houtt ) AND THE APPLICATION AS ANTIBACTERIAL AGENT
Authors: Arief Dede Zaenal , Velly Hervelly
Published: March 2018

The purpose of this research is to determine the most effective of nutmeg meat products to inhibit the specific spoilage bacteria based on inhibitory zone and determine the power of antibacterial compounds in nutmeg meat to  inhibit and kill specific spoilage bacteria  based on the number of growth  of spoilage bacteria. This research consists of two stages: The purpose of first stage is to determine  the most effective of nutmeg meat products as an antimicrobial agent to inhibit gram-positive and gram-negative bacteria with inhibition test response. The second stage of the main research continued from  preliminary research that consists of three steps. The purpose of first step is to determine  the best long immersion antimicrobial substances against bacteria growth in fresh meat for 0 minute, 5 minutes, 10 minutes, 15 minutes and 20 minutes. The purpose of second step is to determine the correlation between the concentration of antimicrobial agent 5%, 10%, 15%, 20% and 25% of the microbial growth number in fresh meat stored within 5 days. The analysis was performed using total plate count method. The purpose of third  step is to determine the level of concentration that is acceptable to consumers. Based on the results of research was obtained that the nutmeg meat essential oil can inhibit the growth of gram positive and negative bacteria. If concentration of antimicrobial substances are higher, so that the power of inhibit to against spoilage bacteria  in fresh meat is higher. The selected concentration by organoleptic test that acceptable by consumers is 10%.
PENAMBAHAN KONSENTRASI BAHAN PENSTABIL DAN SUKROSA TERHADAP KARAKTERISTIK SORBET MURBEI HITAM
Authors: Cahyadi Wisnu , Widiantara Tantan
Published: March 2018

Sorbet merupakan salah satu makanan pencuci mulut dimana berasal dari pencampuran sari buah, sukrosa dan bahan penstabil yang memiliki bentuk menyerupai es krim. Penelitian ini bertujuan untuk mengetahui penambahan konsentrasi bahan penstabil dan sukrosa serta interaksi keduanya terhadap karakteristik sorbet murbei hitam. Metode penelitian dilakukan dalam dua tahap, yaitu penelitian pendahuluan dan penelitian utama. Penelitian pendahuluan yang dilakukan adalah menentukan bahan penstabil yang terpilih menggunakan uji organoleptik. Pada uji organoleptik penelitian pendahuluan memiliki tahapan yang terdiri dari sortasi buah murbei, trimming, pencucian, penirisan, blanching, penghancuran, pencampuran sukrosa dan bahan penstabil, pemasakan, temperring, pembekuan dengan ice cream maker, penyimpanan beku. Sedangkan pada penelitian utama yaitu menentukan konsentrasi bahan penstabil CMC dan sukrosa menggunakan metode RAK (Rancangan Acak Kelompok). Tahapan penelitian utama terdiri dari sortasi buah murbei, trimming, pencucian, penirisan, blanching, penghancuran, pencampuran sukrosa dan bahan penstabil CMC, pemasakan, temperring, pembekuan dengan ice cream maker, penyimpanan beku. Bahan penstabil yang terpilih di penelitian pendahuluan yaitu CMC. Hasil dari penelitian utama menunjukkan bahwa konsentrasi bahan penstabil berpengaruh terhadap tekstur, overrun, kadar air dan vitamin C. Konsentrasi sukrosa berpengaruh terhadap rasa, aroma, tekstur, kadar air dan vitamin C. Interaksi antara konsentrasi bahan penstabil CMC dan konsentrasi sukrosa berpengaruh terhadap tekstur dan kadar air. Hasil penelitian menunjukkan bahwa produk sorbet murbei hitam terpilih adalah perlakuan sampel a3b3 (konsentrasi CMC 0,3% dan konsentrasi sukrosa 25%), karena dilihat dari uji organoleptik merupakan sampel yang paling disukai panelis dengan aktivitas antioksidan 1954,388 ppm, kadar air 65,76%, vitamin C 22,16 mg/100 g bahan, dan overrun 25,30 %.
OPTIMALISASI FORMULASI MINUMAN JELLY LIDAH BUAYA (Aloe vera L.) DAN DAUN BLACK MULBERRY (Morus nigra L.) MENGGUNAKAN DESIGN EXPERT METODE MIXTURE D-OPTIMAL
Authors: Taufik Yusman , Widiantara Tantan
Published: March 2018

Tujuan dilakukan penelitian ini adalah untuk memperoleh formulasi optimal dalam pembuatan minuman jelly lidah buaya dan daun black mulberry menggunakan program Design Expert metode Mixture D-Optimal. Penelitian ini meliputi lima tahap yaitu analisis bahan baku, penentuan variabel dan penentuan respon, penentuan formulasi dengan Design Expert metode Mixture D-Optimal, pembuatan produk dan pengujian respon produk minuman jelly lidah buaya dan daun black mulberry dengan formulasi dari program Design Expert metode Mixture D-Optimal, tahap terakhir penentuan formulasi terpilih dan pengujian formulasi terpilih. Formulasi optimal yang telah diprediksi oleh program Design Expert metode Mixture D-Optimal memiliki nilai ketepatan (desirability) 0,699 dengan kadar air 80,44%, kadar vitamin C 13,14 mg/100g, pH 5,1, viskositas 270 mpas, sineresis 6,78%, uji hedonik atribut warna 3,45, atribut aroma 3,32, atribut rasa 3,72, dan atribut tekstur 4,2. Berdasarkan hasil tersebut menunjukkan bahwa program Design Expert metode Mixture D-Optimal dapat menentukan formulasi optimal minuman jelly lidah buaya dan daun black mulberry.
PENGARUH KONSENTRASI BUBUR BUAH DAN TEPUNG KEDELAI TERHADAP KARAKTERISTIK FIT BAR BLACK MULBERRY
Authors: Achyadi Nana Sutisna , Taufik Yusman , Khairunissa Darin Intan
Published: March 2018

Tujuan penelitian ini untuk memperoleh produk pangan darurat dan diharapkan sebagai alternatif produk pangan yang memiliki kandungan gizi lengkap sehingga dapat memenuhi kebutuhan energi. Penelitian ini menggunakan rancangan percobaan faktorial 3x3 dalam rancangan acak kelompok (RAK) dalam ulangan sebanyak 3 kali, dimana faktornya meliputi : pengaruh konsentrasi bubur buah (A) yang terdiri dari tiga taraf, yaitu a1 (5%), a2 (10%), a3 (15%) serta konsentrasi tepung kedelai (B) yang terdiri dari 3 taraf, yaitu b1 (14%), b2 (16%), b3 (18%). Respon pada penelitian ini adalah respon kimia, yaitu kadar protein, kadar karbohidrat, dan kadar lemak. Respon fisik yaitu kekerasan. Respon organoleptik yang meliputi warna, rasa, dan tekstur dan pengujian aktivitas antioksidan pada sampel terpilih.Konsentrasi bubur buah berpengaruh nyata terhadap kadar karbohidrat, kadar protein, kadar lemak, kekerasan, rasa, dan warna. Konsentrasi tepung kedelai berpengaruh nyata terhadap kadar karbohidrat, kadar protein, kadar lemak, tekstur, dan kekerasan. Interaksi antara konsentrasi bubur buah dan tepung kedelai berpengaruh nyata terhadap kadar karbohidrat, kadar protein, kadar lemak, dan kekerasan pada fit bar black mulberry. Berdasarkan respon fisik dan respon kimia yang telah dilakukan a3b3 (konsentrasi bubur buah 15% dan konsentrasi tepung kedelai 18%) adalah prduk terpilih dengan kadar karbohidrat 43,21%, kadar protein 11,53%, kadar lemak 9,23%, kekerasan 2,15 mm/sec/100 gram, dan aktivitas antioksidan sebesar 139,480 ppm (sedang).
Presencia y distribución de la lengua maya yucateka en la península de Yucatán del clásico al posclásico tardío.
Authors: Voss Alexander W.
Published: March 2018

La presencia y distribución de los hablantes de la lengua maya yucateka en la Península de Yucatán del clásico temprano hasta el momento de contacto con los españoles son estudiadas mediante un análisis de las inscripciones jeroglíficas bajo los planteamientos de la teoría de la semiótica integracional. Siendo la lengua escrita un producto cultural que sirve como medio de comunicación alterno a la lengua hablada, una hipótesis que plantea que una lengua hablada en cierta área geográfica tiende a dejar sus rasgos particulares en el código de las inscripciones debe de considerar, aparte de los aspectos lingüísticos de la lengua bajo estudio, los factores biomecánicos, macrosociales y circunstanciales que interfieren en su manifestación gráfica-visual. Complementando los avances de la lingüística histórica y epigrafía o gramatología en el campo de los jeroglíficos mayas con la información lingüística, geográfica, histórico-cultural y social documentada en las fuentes coloniales, se elabora una propuesta integral para el proceso de la expansión de los hablantes del maya yucateko en la época prehispánica. Original recibido: 2016/08/31Dictamen entregado al autor: 2017/02/28, 2017/05/15Aceptado: 2017/10/26
Pengaruh Sumber Informasi Terhadap Keputusan Masuk Universitas Muhammadiyah Palembang
Authors: Asiati Diah Isnaini
Published: March 2018

This research is developed using an associative design with connecting the variables of personal resource, commercial resource, public resource, and experience resource, to the decision of chosing UMP. There are five variables which are developed into several indicators. The number of sample is determined by a formula or Isaac Michael with the fault rate at 5%. There are 207 students who taked by proportional cluster sampling. The required data is the primary data in the form of respondent answers. Then the data analysis method is multiple linear regression. The obtained results are the R value of 0.723 which means that there is a strong relationship positively and significantly between personal resource, commercial resource, public resource, and experience resource, to the student decision
Central sleep apnea – a case report
Authors: Dybala Andrzej , Dyczko Monika , Makaruk Boguslaw , Kicinski Pawel , Bartoszek Elzbieta , Myslinski Wojciech , Rahnama Mansur , Mosiewicz Jerzy
Published: March 2018

Central sleep apnea (CSA) is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe CSA, who was successfully treated with BiPAP ST equipment.
Implant-supported prostheses versus conventional permanent and removable dentures
Authors: Koszuta Agnieszka , Szymanska Jolanta
Published: March 2018

Social, economic and technological progress results in an increasing range of treatment and rehabilitation methods for patients with partial or complete edentulism. The role of the dentist is to inform the patient about the full range of available missing teeth treatment options leading to complete rehabilitation of the masticatory organ in agreement with the patient’s aesthetic and functional expectations. The aim of the paper was to identify the type of prostheses used by patients before opting for implantsupported teeth replacements, according to the patients’ age, sex, marital status, place of residence and education. The study covered 464 patients, women and men, aged 20-74, treated with dental implants. The patients answered questions in an anonymous questionnaire. The influence of the prosthetic replacement type according to age and marital status was highly statistically significant, whereas it was statistically significant according to sex, place of residence and education. The female respondents who previously used tissue-borne complete or partial dentures opted for implant treatment more frequently. The respondents younger than 40 and between 40-60 years of age who did not previously used any prosthetic replacements opted for implant treatment more frequently. The respondents who did not use any prosthetic replacements decided to undergo implant treatment most frequently, regardless of their marital status, education and place of residence. The patients opted for implant treatment to improve their quality of life, despite the high cost of such therapy.
Evaluation of chromium, nickel, iron and manganese content in wheat, flour, bran and selected baked products
Authors: Bawiec Piotr , Halabis Magdalena , Marzec Zbigniew , Kot Andrzej , Solski Janusz , Gawel Kinga
Published: March 2018

Considering the nutritional values, breadstuff plays a big part in covering human nourishment needs and constitutes a base of all day diet. Moreover, bread is an excellent source of numerous vitamins and minerals the abundance of which depends on the degree of grinding. Thus, it seems to be very important to know the composition and level of bio-elements. That is why the main target of this study was to evaluate the concentration of selected trace elements: chromium (Cr), nickel (Ni), iron (Fe) and manganese (Mn) in wheat grain, wheat bran, different wheat and rye flour types and variety of breadstuff also with addition of grains and seeds from different bakeries and mills. Another task was to analyze if the technological process has an influence on secondary despoil of bread goods with heavy metal elements. The analyzed trace elements were measured with a precise and accurate atomic absorption spectrophotometric method (AAS) and the results were expressed in mg/kg of selected sample. Obtained results show that bread and grain products are a good source of trace elements like chromium, nickel, iron and manganese. However, the higher levels of chromium and nickel in bread goods could rather be an effect of impurity caused by a technological process in mill and bakeries.
Zero crossing and ratio spectra derivative spectrophotometry for the dissolution tests of amlodipine and perindopril in their fixed dose formulations
Authors: Maczka Paulina , Gumieniczek Anna , Galeza Justyna , Pietras Rafal
Published: March 2018

Dissolution tests of amlodipine and perindopril from their fixed dose formulations were performed in 900 mL of phosphate buffer of pH 5.5 at 37°C using the paddle apparatus. Then, two simple and rapid derivative spectrophotometric methods were used for the quantitative measurements of amlodipine and perindopril. The first method was zero crossing first derivative spectrophotometry in which measuring of amplitudes at 253 nm for amlodipine and 229 nm for perindopril were used. The second method was ratio derivative spectrophotometry in which spectra of amlodipine over the linearity range were divided by one selected standard spectrum of perindopril and then amplitudes at 242 nm were measured. Similarly, spectra of perindopril were divided by one selected standard spectrum of amlodipine and then amplitudes at 298 nm were measured. Both of the methods were validated to meet official requirements and were demonstrated to be selective, precise and accurate. Since there is no official monograph for these drugs in binary formulations, the dissolution tests and quantification procedure presented here can be used as a quality control test for amlodipine and perindopril in respective dosage forms.
A rare case of retained fourth molar teeth in maxilla and mandible. Case report
Authors: Rahnama Mansur , Szyszkowska Anna , Pulawska Marta , Szczerba-Gwozdz Joanna
Published: March 2018

The study presents a case of the rarely occurring totally retained fourth molar teeth simultaneously in maxilla and mandible. The appearance of supernumerary teeth is a relatively uncommon dental anomaly and it is rare for patients to have impacted fourth molars in two quadrant. The aim of this work is to describe the presence of unilateral (right) fourth molars in the maxilla and the mandible in a young female patient aged 24 years. Orthopantomogram revealed impacted lower third molars but also unerupted unilateral (right) upper and lower fourth molars. Before orthodontic treatment, the patient was subsequently admitted for removal of third and fourth impacted upper and lower molars under local anesthesia.
Collagenases and gelatinases in bone healing. The focus on mandibular fractures
Authors: Kurzepa Jacek , Baran Marcin , Watroba Slawomir , Barud Malgorzata , Babula Daniel
Published: March 2018

Due to high amount of collagen fibres in the structure of bone, the enzymes capable of collagen digestion play a key role in bone remodelling. Matrix metalloproteinases (MMPs), prevailing extracellular endopeptideses, can digest extracellularly located proteins, e.g. collagen, proteoglycans, elastin or fibronectin. Among MMPs, collagenases (MMP-1, MMP-8 and MMP-13) and gelatinases (MMP-2 and MMP-9) can cleave collagen particles to forms that are able to undergo further steps of catabolism intracellularly. In addition, activity of the gelatinases (as an activation of proinflammatory cytokines) facilitates spreading inflammation that is necessary during the first stage of bone healing. Further studies related to the role of various MMPs in mandibular fractures should precisely explain their function in the bone healing and evaluate the influence of MMPs inhibitors on that process. This review provides the basic information about two groups among MMPs family, collagenases and gelatinases, and their role in repairing processes after mandibular fractures.
rapid detection for the inhibition of phosphoglucose isomerase from Escherichia coli by mercury(II) chloride based on TLC-autographic analysis – preliminary studies
Authors: Paradowska Katarzyna , Lutek Joanna , Ginalska Grazyna
Published: March 2018

The quest for new techniques for screening inhibitors of phosphoglucose isomerase is crucially important owing to therapeutic control of chronic bacterial infections associated with the biosynthesis of bacterial biofilm. According to the new method, yellowish zones against the purple background could be visually observed where phosphoglucose isomerase activity was inhibited. The new protocol with NADPH/NBT/PMS staining for TLC-autographic method was able to detect PGI inhibition by pure reference substance as mercury(II) chloride.
EKSPLORASI TUMBUHAN YANG BERPOTENSI SEBAGAI PENGHASIL MINYAK ATSIRI DI LOMBOK TIMUR-NTB
Authors: TIRTA IG. , AGUS HENDRA WIBAWA I PT.
Published: March 2018

The number of natural biological resources of Indonesia to growing ideas to increase the sale value of plant products especially plant essential oil. Studies of essential plant species that have been common in the market has a lot to do, but for the species of plants are still limited. Exploration is required to get a new species essential oil to be applied to society. Exploration is one of the first steps in this activity to collect the species of plants thathave the potential as a producer of essential oils. Exploration conducted in Lombok-NTB April 16 sd May 1, 2014 Acquisition of exploration results as much as 21 numbers were suspected to contain a collection of essential oils. Additional new collections for the Botanical Gardens ‘Eka works’ Bali as much as 2 species.
KEANEKARAGAMAN IKAN (PISCES) DI DANAU SIPOGAS KABUPATEN ROKAN HULU PROVINSI RIAU
Authors: FAUzIAH PUjI , ANTHONIUS PURNAMA ARIEF , YOLANDA ROFIZA , KARNO RIA
Published: March 2018

This study has been conducted from May to July 2016 to inventory the species of fish from Sipogas lake, Rokan Hulu District, Riau Province. Result showed a total of 353 individuals of fish belonging to 3 order, 7 families, 13 genera and 14 species were recorded in this study, by using survey method at 4 stations, namely Anabas testudineus, Barbodes gonionotus, Belontia hasselti, Channa striata, Cyclocheilichthys apogon, Hampalamacrolepidota, Helostoma temminckii, Kryptopterus limpok, Ompok eugeneiatus, Osteochilus hasseltii, Osteochilus mycrocephalus, Pristolepis grooti, Puntius lateristriga and Rasbora sp. Cyprinidae was the predominant fish in this study.
AKTIVITAS ANTIBAKTERI FILTRAT Streptomyces sp. KCM2 TERHADAP MULTIDRUG RESISTANT Acinetobacter baumannii SECARA IN VITRO
Authors: LOSIANI NI KADEK , KAWURI RETNO , DARMADI A. A. KETUT
Published: March 2018

Acinetobacter baumannii is one of the pathogen which leads to multidrug resistant (MDR-A baumannii). This pathogen is often causing outbreaks of infections to the patients which are receiving treatment in the intensive care unit in hospital. This study aims to find out the antibacterial activity and the Minimum Inhibitory Concentration (MIC) of Streptomyces sp. KCM2 filtrate in inhibiting the growth of MDR-A baumannii. Streptomyces sp.KCM2 isolates was isolated in rhizosphere of white turmeric (Curcuma mango Val.) (Losiani et al., 2016). MDRA. baumannii isolates were obtained from stock culture in Clinical Microbiology Laboratory Sanglah Hospital in Denpasar. The antibacterial and the MIC test of Streptomyces sp. KCM2 filtrate was using the wells diffusion method. The research design was used Completely Randomized Design (CRD) and the inhibitory zone diameterdata of MIC test were analyzed by Analysis of Varian (ANOVA), and then continued by Duncan Multiple Range Test in significance level 5%. The results of this study showed that the Streptomyces sp. KCM2 filtrate was able inhi biting with diameter zone of 23,44 mm and MIC of filtrate was 4% (v/v) with inhibition zone diameter of 8.77 mm.
PENGARUH KONSENTRASI ROOTONE-F DAN PANJANG SETEK PADA PERTUMBUHAN Rhododendron mucronatum G. Don. var. phoeniceum
Authors: M.S. PUTRI DYAN
Published: March 2018

Rhododendron mucronatum G. Don. var. phoeniceum is one of ornamental plants that have high economic value and aesthetics. Problems that often experienced in propagation this plant are difficulties in producing roots on cutting and limited availability of seeds on the market. This study aims to determine the effect of plant growth regulators (Rootone-F) and length of stem cuttings on the growth of R. mucronatum G. Don. var. phoeniceum. This study employed completely randomized block design with two factors and three replications. The first factor is concentration of Rootone-F (0, 150, 300, and 450 mg/L) and the second factor is length of stem cuttings (15; 25; and 35 cm). The results showed that the concentration of Rootone-F and cuttings length has significant effect (? <0.01) to number of leaves, roots and seedling height; and cuttings length was highly significant (? <0.05) to the seedling height. Rootone-F optimum concentration for the cuttings growth of shoot R. mucronatum G. Don. var. phoeniceum is 450 mg/L which is indicated by the average value of the number of leaves as much as 8.8 leaves, the average value of the number of roots as much as 9.6 and a mean value of 0.90 cm tall seedlings when compared with controls. Cuttings with 35 cm long provide seed growth R. mucronatum G. Don. var. phoeniceum. The highest indicated by the mean number of leaves as much as 6.6 leaves, the average value of the number of roots of 8.6 and a mean value of 0.88 cm additional seedlings height compared to cuttings at 15 cm length and 25 cm.
KEANEKARAGAMAN FORAMINIFERA BENTIK TELUK BALIKPAPAN, PROVINSI KALIMANTAN TIMUR
Authors: WIDIANINGSIH MASTUTI
Published: March 2018

Balikpapan Bay is one of locations of sampling sediments for the study of benthic foraminifera. The objective of this research was to determine the diversity of benthic foraminifera at different depths at Balikpapan Bay, East Kalimantan. Samples was selected at  depth of 0-20 m, then divided into 4 depths, 0-5 m, 6-10 m, 11-15 m, and 16-20 m. A total of 1553 specimens were obtained from 66 species, 7 ordo, and 17 family. Asterorotalia trispinosa is a species with the highest of abundance, that followed by Rotalia sp.1, Rotalia sp.2, and Trichammina nana. The diversity index of each sampling point was different, 8 points have stable diversity, 11 moderate points, and 1 unstable point. This condition were influenced by depth, brightness, temperature, pH, turbidity, salinity, and DO at each sediment sampling point.
Organik Tarımda Bazı Yeni Yöntemlerle Yabancı Ot Kontrolü
Authors: Yıldız Taner , Özkaraman Fikret , Kandemir Dilek
Published: March 2018

The chemicals used for weed control cause pollution at both ground and surface waters, and lead to accumulation of pesticide residues in vegetables, fruits and field crops. For this reason, avoiding of use of chemicals and instead applying natural production methods (organic farming) emerged as a people desire. In recent times, the environmental consciousness has increased rapidly all over the world and potential dangers related to use of chemicals led scientists and people to worry. There have been extensive studies on different methods and machines, which can be used for weed control, as they do not leave any residues at soil and water sources. In this study, some new weed control methods were included that can be applied in organic farming.
Vocational High School Students Ability in Mathematics Literacy
Authors: Ciptaningtyas Asih , Mardiyana Mardiyana , Pratiwi Hasih
Published: March 2018

Mathematical literacy is a person's ability to formulate, apply, and interpret mathematics in various contexts. This study is a qualitative descriptive that aims to describe the ability of mathematics literacy of students in thesubject of exponents and logarithms in Vocational High School. Data analysis is done by collecting data, reducing data, and verifying data. The results obtained in this study are subjects with values above the MEC cansolve the problem by using information, performing representations based on concepts, using procedural knowledge in the form of algebraic manipulation in accordance with the nature of exponents and logarithms,and can connect it with the real world to determine the outcome of completion, according to level 4 PISA. Subjects with the same value as MEC can solve problems, interpret by using the properties of exponents andlogarithms, and implement procedures according to the 3rd level of PISA. Subjects below the MEC can only solve commonly resolved problems using simple properties, corresponding to the PISA 1st level.
Local Economic Governance and the Development of the Business Sector in Vietnam
Authors: Thuy Dao Thi Bich
Published: March 2018

Abstract:Local economic governance plays an important role in the development of the business sector. To assess its impact on business sector growth in Vietnam, this empirical study is conducted at the local level with all 63 provinces nationwide in the period from 2006 to 2014. The Provincial Competitiveness Index (PCI) is used as a measurement for local economic governance. The finding reveals that overall the PCI has a positive effect on growth in the number of enterprises and output generated in the business sector. At the sub-index level, 5 indicators show positive effects with labor training having the largest impact, followed by time costs of regulatory compliance, informal charges, transparency and finally business support service. Land access and security of tenure and proactivity of the provincial leadership unexpectedly show negative effects while the other 2 indicators, including entry cost for new firms and legal institutions, have no significant impact on business sector growth.

Keywords

Local economic governance, Provincial Competitiveness Index, business sector growth
Comunicación publicitaria en la industria de la moda: branded content, el caso de los fashion films
Authors: Arbaiza Rodriguez Francisco , Huertas García Shirley
Published: March 2018

El presente artículo aborda una de las nuevas tendencias de publicidad, el branded content, una fórmula que da un paso más allá del product placement y procura al consumidor un contenido relevante. En concreto, se analiza el caso de los fashion films, un formato publicitario que ha irrumpido en el sector de la moda y los productos de lujo con mucho éxito, y cuyo fundamento consiste en formular un contenido creado específicamente para determinada marca de moda, con una composición en el que predomina la belleza y la estética, pero que, sobre todo, permite comunicar los valores y personalidad de marca y así conectar con el consumidor.
REPRESENTASI KEKUASAAN DALAM IMBAUAN DI RUANG PUBLIK (POWER REPRESENTATION IN PUBLIC SPACE APPEAL)
Authors: Wahyuni Sri
Published: March 2018

Imbauan di ruang publik merupakan suatu ajakan, imbauan, dan peringatan pada ma-syarakat untuk melaksanakan apa yang dikehendaki oleh pembuat imbauan (pengua-sa). Dengan demikian, bahasa merupakan unsur penting dalam penerapan kekuasaan. Penelitian ini mengkaji representasi kekuasaan pada imbauan di ruang publik dengan berdasarkan empat aspek kekuasaan, yaitu pandangan dominatif individu atau ke-lompok terhadap individu atau kelompok yang lain, jarak sosial, praktik dominasi, dan praktik membangun kekuasaan. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Hasil penelitian ini menunjukkan adanya representasi kekuasaan pada imbauan di ruang publik.Appeal in public space is a request, direction, and warning to public to carry out what is required by the makers of the appeal (the ruling). Thus, language is an important element in the exercise of power. This study examines the power representation on the public space appeal based on four of power aspects, namely individual or group dominative perspective to other individual or group, social distance, the practice of domination, and the practice of building power. The method used in this study is a qualitative descriptive method. The research result showed that there was a tendency of power representation.
STRATEGI KEPENYAIRAN IMAN BUDHI SANTOSA DALAM ARENA SASTRA: KAJIAN SOSIOLOGI PIERRE BOURDIEU (POETRY STRATEGY OF IMAN BUDHI SANTOSA IN LITERARY FIELD: A STUDY ON SOCIOLOGY PIERRE BOURDIEU)
Authors: Zamzuri Ahmad
Published: March 2018

Iman Budhi Santosa (IBS) di arena sastra Yogyakarta dikenal sebagai penyair legitimet, baik dipandang dari kualitas karya maupun konsekrasi dalam dunia sastra. Posisi IBS berkaitan erat dengan Persada Studi Klub (PSK), komunitas sastra yang dibimbing oleh Umbu Landu Paranggi. Penelitian ini akan mengkaji strategi IBS dalam mencapai posisi saat ini. Tujuan penelitian ini untuk mengetahui strategi IBS dalam mencapai posisi penyair saat ini dengan menggunakan teori sosiologi Pierre Bourdieu. Penelitian ini bersifat deskriptif. Dari hasil analisis menunjukkan bahwa IBS cenderung meng-gunakan strategi simbolik dalam pencapaiannya sebagai penyair dan posisinya sebagai pengasuh para penulis.Iman Budhi Santosa (IBS) in Yogyakarta literary arena known as a legitimate poet, either seen from his works quality or his consecration in the literary world. IBS position is closely related to Persada Studi Club (PSK), which is guided by Umbu Landu Paranggi. This study investigates the IBS strategy in achieving his current position. The research aims to find out IBS strategy in achieving the poet current position by using Pierre Bourdieu sociology theory. The research is a descriptive study. The analysis shows that IBS tends to use symbolic strategy in his achievement as a poet and his position as a tutor for writers.
FUNGSI SOSIAL KEMASYARAKATAN TEMBANG MACAPAT (COMMUNITY SOCIAL FUNCTIONS OF MACAPAT)
Authors: Santosa Puji
Published: March 2018

Penelitian ini bertujuan mengungkapkan dan mendekripsikan fungsi sosial kemasyarakatan tembang macapat. Masalah penelitian adalah bagaimanakah tembang macapat difungsikan dalam kehidupan sosial kemasyarakatan. Seiring dengan tujuan dan masalah itu, metode yang digunakan adalah metode kualitatif dengan ditopang teori fungsi sastra yang bertolak dari tesis dan kontratesis Horatio, dulce dan utile. Hasil penelitian membuktikan bahwa tembang macapat dari awal keberadaannya, abad XIV Masehi, hingga kini dimanfaatkan dalam kehidupan sosial kemasyarakatan, antara lain, sebagai hiburan, estetika, pendidikan, pementasan tradisional, sarana surat-menyurat, senandung teman bekerja, mantra penolak bala, upacara temu temanten adat Jawa, upacara kegiatan Pangestu, dan filosofi siklus kehidupan. Atas dasar fungsi sosial kemasyarakat tersebut menjadikan tembang macapat sebagai karya sastra yang begitu urgen dalam kehidupan manusia sebagai tontonan, tuntunan, dan tatanan.This study aims to reveal the social and decrypt functions macapat. The research problem is how macapat functioned in social life. Along with the purpose and the problem was, the method used is a qualitative method supported by the theory of functions of literature that departed from the thesis and kontratesis Horatio, dulce and utile. The research proves that macapat from the beginning of its existence, the fourteenth century AD, until now used in social life, among others, as entertainment, aesthetics, education, staging traditional, means of correspondence, humming a friend works, spells repellent reinforcements, ceremonial gathering temanten Javanese tradition, ceremony Pangestu activities, and philosophy of the life cycle. On the basis of the social function of the society, it makes macapat as a literary work that is so vital in human life as a spectacle, guidance, and order.
TRANFORMASI KISAH �ASHABUL KAHFI� DALAM AHLUL KAHFI KARYA TAUFIQ AL-HAKIM (TRANSFORMATION STORY "ASHABUL KAHFI" IN AHLUL KAHFI BY TAUFIQ AL-HAKIM)
Authors: Sidik Umar
Published: March 2018

Tulisan ini bertujuan untuk (1) mendeskripsikan bagaimana resepsi pengarang dalam menempatkan kisah Ashabul Kahfi dalam karyanya yang berjudul Ahlul Kahfi; dan (2) menemukan hubungan interteks antara naskah drama dan teks Alquran serta tafsirnya sebagai hipogram.Pendekatan yang digunakan dalam pengkajian ini ialah resepsi/transformasi.Teknik analisis dilakukan dengan cara membandingkan, menjajarkan, dan mengontraskan teks drama Ahlul Kahfi dan Alquran sebagai hipogram. Hasil yang didapatkan dari penelitian ini bahwa naskah drama Ahlul Kahfi merupakan penyerapan, penyalinan, enovasi, dan transformasi dari Alquran.Terdapat jalinan yang erat antara kisah Ashabul Kahfi dan Ahlul Kahfi sebagaihasil karya inovasi dan transformasi.Drama Ahlul Kahfi muncul karena adanya kisah Ashabul Kahfi.This paper aims to (1) describe how the reception of the author in involving the story of Ahlul Kahfi in his work entitled Ashabul Kahfi; and (2) find the intertextual relationship between the playwright and the Quran text and its interpretation as hipogram. The approach used in this study was reception/transformation. The analysis was conducted by comparing, aligning, and contrasting the drama text, Ahlul Kahfi and the Quran as hipogram. The results shows that the playwright, Ahlul Kahfi is the absorption, copying, enovation, and transformation from the Quran. There is a close relation between the story of Ashabul Kahfi and Ahlul Kahfi as the work of innovation and transformation. Ahlul Kahfi arise drama appearance was initiated by the story of Ashabul Kahfi.
PEPINDHAN TENTANG AKTIVITAS MANUSIA DALAM BAHASA JAWA (JAVANESE PEPINDHAN OF HUMAN ACTIVITY)
Authors: Setyaningsih Nur Ramadhoni
Published: March 2018

Penelitian ini merupakan penelitian linguistik interdisipliner untuk menemukan hubungan antara bahasa dan budaya, yakni budaya Jawa. Tujuan khusus yang ingin dicapai ialah (1) mendeskripsikan bentuk-bentuk pepindhan aktivitas manusia, (2) menemukan objek pembanding pepindhan aktivitas manusia, serta (3) mendeskripsikan unsur-unsur budaya yang tampak dalam pepindhan aktivitas manusia. Proses analisis data dilakukan dengan pendekatan linguistik antropologi. Berdasarkan kajian yang dilakukan dapat disebutkan bahwa aktivitas manusia yang di-pepindhan-kan meliputi aktivitas kaki, mulut, tangan, dan aktivitas tubuh secara keseluruhan. Kosakata yang digunakan sebagai pembanding dalam pepindhan diambil dari benda atau sesuatu yang dikenal baik oleh masyarakat Jawa dan mencerminkan kondisi budaya masyarakat Jawa. Penanda perbandingan yang muncul ialah kaya, kadya, pindha, semu, serta penasalan dan penambahan imbuhan hanuswara. Unsur budaya Jawa yang tercermin dari penggunaan kosakata dalam pepindhan ialah matapenca-harian, peralatan hidup, kesenian, dan pengetahuan.This study is interdisciplinary linguistic research that is aimed to find out the relation between language and the culture, particularly Javanese culture. The specific objectives are (1) to describe forms of human activity pepindhan, (2) to discover comparison object of human activity pepindhan, and (3) to describe cultural elements that appear in human activity pepindhan. Data analysis process is carried out by linguistic anthropology approach. Based on the study, it can is found out that human activity pephindan are leg activity, mouth activity, hand activity, and a whole body activity. The comparison vocabularies in pepin-dhan are taken from something that are familiar in Javanese community and these words reflect Javanese culture society condition. The comparison markers are kaya, kadya, pindha, semu, and nasalization with hanuswara affix. Javanese cultural elements reflected in pepindhan vocabularies are livelihood, equipment life, arts, and knowledge.
A FUNÇÃO DE CONTROLAR DOS TRIBUNAIS DE CONTAS E O CARÁTER PEDAGÓGICO DA SANÇÃO PECUNIÁRIA
Authors: Costa Jorge Heleno , Filho Carlos Victor Muzzi
Published: March 2018

Essa pesquisa analisa parte do sistema de controle exercido pelos Tribunais de Contas. Estuda-se, mais especificamente, a eficácia e a eficiência das sanções pecuniárias, propondo-se outras técnicas de controle, haja vista os objetivos finalísticos da própria atividade de controle. Basicamente, discute-se a existência, ou não, do caráter pedagógico na sanção pecuniária, utilizando-se de pesquisa bibliográfica, pelo método dedutivo, com marco teórico na ideia de controle de Ana Carla Bliacheriene. Finalmente, propõe-se a adoção de outros mecanismos, distintos da sanção pecuniária, que permitam aos Tribunais de Contas contribuírem para o aperfeiçoamento da gestão pública.