bluuebunny/crossref_metadata_2025 huggingface dataset:
DREAM GENERATION USING AI: COMPARISON OF ALGORITHMS
Authors: - JWALA JOSE , - DR. B. SURESH KUMAR , - PRASEETHA N A
Published: December 2024

Dream generation is an emerging field within artificial intelligence that aims to replicate the human experience of dreaming through computational models. This paper compares various AI algorithms used for dream generation, evaluating their performance, creativity, and computational efficiency. We explore Generative Adversarial Networks (GANs), Variational Autoencoders (VAEs), and Transformer-based models, providing a comprehensive analysis of their strengths and weaknesses. Our results indicate that each model has unique advantages, suggesting potential hybrid approaches for future research.
automatic Vehicle Security System with ZigBee Keyless entry over CAN Network
Authors: - Meenakshi Talwar , - Nikhil Kulkarni
Published: December 2024

The proposed work includes integration of ZigBee Keyless entry system with CAN in vehicles. ZigBee offers wireless Keyless access, while CAN serves as the vehicle's communication backbone. This allows security estimate averse to unauthorized access users advanced features while ensuring robust protection. through meticulous examination, it underscores the feasibility and benefits of this integration, heralding a new era of sophisticated, secure vehicle access and operation in the automotive industry. through careful analysis, it demonstrates that this integration is both feasible and advantageous, so ushering in a new era of sophisticated and secure vehicle access and operation within automotive industry.
Physical Education Various Sports Training: A Systematic Review
Authors: - Dr.S.KARTHICK
Published: December 2024

Physical Education (PE) is a crucial component in promoting character education, physical health, psychosocial and motor skills. Physical learning activities at school can provide a healthy lifestyle. Sports Training for development and performance preparation in team sports such as soccer through played-form activities is getting widely discussed and increasingly recommended in sport organizations at all ages and skill levels. Continuous training is a type of exercise that involves repetitive movements at a continuous intensity without rest periods. Fartlek is a running training method that involves alternating between faster and slower running paces. The word "fartlek" is Swedish for "speed play”. Interval training consists of repeated rounds of exercise that can range from a few seconds to several minutes. Plyometrics, also known as jump training or plyos, are exercises in which muscles exert maximum force in short intervals of time, with the goal of increasing power (speed-strength). Circuit training is a form of body conditioning that involves endurance training, resistance training, high-intensity aerobics, and exercises performed in a circuit, similar to high-intensity interval training. Conclusion Enhanced Physical Fitness: Sports training focuses on improving athletes' strength, endurance, speed, agility, flexibility, and coordination.
Waterways and Roads in the Pre-colonial Bengal Delta: A Historical Perspective
Authors: - Md Mamunur Rashid , - Nasir Ahmad
Published: December 2024

The paper reviews the general conditions of the transport networks in the pre-colonial Bengal Delta. This region has a rich history of political dynamics, a thriving economy, and active commercial ventures. In the pre-colonial period, two primary transport systems operated in the Bengal Delta: waterways, due to the riverine and coastal landscape, served as the main mode of communication, while road transport was utilised in the areas where water transport was minimal. Variations in nature, capacity, shape, and functionality of these transport systems were influenced by the distinct geo-environmental features of the region. This paper serves as an in-depth exploration of pre-colonial transport systems, providing a foundation for understanding the evolution of modern transportation in Bengal.
Negation of Copular Sentences in Kannada and Telugu
Authors: - D Amba , - Ria Mukherjee
Published: December 2024

Typology of negation has been much described and discussed over the years. However, focus has mainly been on standard negation. Studies on non-verbal negation in general and comparative studies using the same language family covering the complete domain of non-verbal negation in particular are less common. The strategies to express non-verbal negation vary among languages. In some languages the negation strategy employed in standard negation is also used in non-verbal negation. This study examines and describes negation strategies in Kannada and Telugu languages, both though being the part of the same Dravidian family exhibit differences in the sentence construction. The results suggest that Kannada uses one word to negate the copular sentences whereas Telugu uses two words, one showing an accord and another showing no accord.
Uniqueness of Albumin as a Carrier in Nanodrug Delivery
Authors: - SACHIN A. PANDHARE , - KOMAL MORE , - D.K.VIR , - VISHAL P. JADHAV
Published: December 2024

ABSTRACT

In contemporary medicine, albumin nanoparticles have become a powerful and adaptable nanodrug carrier. The ability of human serum albumin to deliver hydrophobic drugs through passive and active targeting mechanisms demonstrates its versatility in treating a variety of disorders. In addition to discussing ongoing clinical trials using albumin-based formulations, this study emphasizes the benefits of albumin-bound Paclitaxel (Abraxane) over solvent-based formulations (Taxol). Future advancements in albumin-based therapeutics are made possible by the emphasis placed on the importance of albumin in improving drug performance and its potential as a drug delivery mechanism.
Albumin nanoparticles show promise in the treatment of a variety of illnesses. This study emphasizes their use in the delivery of hydrophobic drugs, their benefits over formulations based on solvents, and their ongoing clinical trials. The medicinal potential of albuminNeutrophils, leveraging their inflammation-targeting capabilities, have emerged as innovative drug delivery carriers. Integrating neutrophils with nanotechnology enhances treatment efficacy and reduces side effects. This review explores neutrophil-based nano-drug delivery systems, including membrane-coated nanoparticles, cell-loaded nanoparticles, and chimeric antigen receptor (CAR)-neutrophils. These therapies demonstrate superior biocompatibility, targeting, and therapeutic robustness, showing promise in various disease treatments.Neutrophils, combined with nanotechnology, offer innovative drug delivery. This review covers design principles, mechanisms, and applications of neutrophil-based nano-drug delivery systems, highlighting enhanced biocompatibility, targeting, and therapeutic efficacy.
Automated Testing Strategies for Multi-factor Authentication: a Modern Implementation Guide
Authors: - Kanaka Maheswara Rao Chennuri
Published: December 2024

This comprehensive article explores the automated testing strategies for Multi-Factor Authentication (MFA) systems in modern computing environments. The article examines the evolution of MFA implementation, from basic two-factor models to sophisticated multi-layered verification systems, addressing the challenges and solutions in automating MFA testing processes. The article investigates various authentication methods, including Time-based One-Time Passwords, SMS verification, voice authentication, and biometric factors, analyzing their effectiveness in diverse operational scenarios. It presents detailed insights into testing strategies, development environment setup, and technical implementation approaches while considering security implications and compliance requirements. The article also evaluates contemporary tools and technologies employed in MFA testing automation, examining their impact on security validation and performance optimization. Through comprehensive
article analysis of security considerations, risk assessment methodologies, and implementation guidelines, this article provides a structured framework for organizations implementing automated MFA testing solutions, emphasizing the balance between security requirements and operational efficiency.
Impact of Accounting Information System and Transparency on Good Governance: A Study of Nizamabad Municipal Corporation in Telangana
Authors: - Prof.M.Yadagiri , - K. Ranjitha
Published: December 2024

In order to implement good governance, there are some concepts that have to be considered. The concepts of accountability and transparency are representing the quality of accounting information in any organization. Municipal administration accounting is closely linked with the implementation and accounting treatment in the public domain. It means that the purpose of
Municipal Accounting is to provide the necessary information in order to manage the operations and allocation of resources entrusted to the organization appropriately, efficiently, and economically. It also aims at providing information to report accountability of the management in implementation and to report the results of operations regarding the use of public funds. The quality of Accounting Information System has a very important role in the creation of Transparency and Good Governance. This study is intended to investigate the Impact of
Accounting Information System and Transparency on Good Governance in Nizamabad Municipal Corporation of Telangana State.
Cybersecurity in Hospitals: A Case Analysis of the University of Ghana Medical Centre
Authors: - Richard Aggrey , - Nana Adwoa Dsane , - Karl Osei Afoduo , - Bright Ansah Adjei
Published: December 2024

The University of Ghana Medical Centre Ltd is a premier academic health facility that delivers tertiary/quaternary level health services, education and research in Ghana, Africa and the globe. It is Ghana’s premier quasi health institution and is the only quaternary health centre in Ghana. It is a fully digitalised institution vulnerable to cyberattacks because of patient data, hospital systems, availability of health services and also data of prominent people in society. The paper analysed cybersecurity measures implemented at the health facility to reveal its advantages and disadvantages, and further outlook for its development. The research method comprised an assessment of cybersecurity-related activities, reports and documentation to explore cybersecurity measures and regulatory compliance in explaining timely employee awareness and responding to incidents to protect patients’ details with cybersecurity specialists’ cooperation. The study reports the proactive measures taken by the health facility to avert and mitigate potential cybersecurity threats. However, it also identifies the need for the facility to partner with cybersecurity experts in developing comprehensive response plans, and this comes in recognition of some weaknesses in the current implemented system which are institutional, bureaucratic and technology related.
Skin Cancer Detection using CNN (Convolution Neural Network) with AI Medical Assistant
Authors: - Revathy B D , - Rohan Vijay , - B Ullas , - Sagar N H , - Dhyan M
Published: December 2024

Skin cancer is a very common disease, and with numerous morphological forms and characteristics that are similar between malignant and benign skin lesions, makes the diagnosis pretty difficult. Recent trends in deep learning, with CNNs being the first to enter this domain, have highly facilitated the classification and detection of skin cancer, even in its nascent stages, from images. A plethora of such research works proposed novel architectures for CNNs that may possibly improve the accuracy in the diagnosis of the lesion given as against those belonging to seborrheic keratosis, nevus, or melanoma. The best model, according to the works on these authors, was the multi-layer deep learning model known as SkinLesNet, which performed better than established models such as ResNet50 and VGG16 in all datasets. More extensive studies present a DCNN model that addresses the issue of class imbalance and is stronger than transfer learning models, such as DenseNet and MobileNet. This model achieved strong accuracy on several instances: 98.5% with HAM10000 and 97.1% with ISIC-2019 data. Optimizations in model selection methods: In addition, there existed optimizations in model selection. This was through the application of the multiple-criteria decision making approaches. For instance, the method RAPS can be taken as an example. Through the application of this method, a very significant increase in accuracy was achieved. For optimizing the use of feature selection using Inception V3 in determining diagnosis for oral cavity squamous cell carcinoma, BPSO showed an accuracy of 96.3%. Such breakthroughs underpin therefore the capability of deep learning and AI techniques in raising diagnostic accuracy while cutting costs and making a chance for early intervention of skin and other cancers.
A Comparative study of selected Physical Fitness Variable between Soccer player and Sprinters
Authors: - Megha Gehlot , - Santosh Lamba
Published: December 2024

The aim of the present study way compares the selected Physical Fitness Variables (Flexibility and Endurance) of soccer player and Sprinters (male). Total 50 Subjects were selected (25 from soccer and 25 form sprints), The age ranged from 18-25 year were take as a sample. Physical Fitness test was used to measure the selected Physical Fitness Variables of players. For analysis of the data mean and Standard deviation were calculated and to examine the insignificance difference between the groups mean of different physical fitness variables, independent t-test was applied and level of confidence was set at 0.05 level. Study concluded that significant difference found between the means of selected physical fitness variables such as (Flexibility and Endurance) between Soccer player and Sprinters.
Traditional archaeological drawing : a future vestige or a necessity
Authors:   National University of Kyiv-Mohyla Academy, Husak Anastasiia
Published: December 2024

This article explores the role of archaeological drawing (especially its traditional form) in the development of archaeological knowledge, while also illustrating the generalized process behind the cognitive and mental models of archaeological thought. Archaeological drawing, being subjective in its interpretative nature, serves as an important method of critical observation and analysis of archaeological objects and artifacts.
The main discussion focuses on the necessity of preserving the «traditional» type of drawing in modern archaeology amid rapid digitalization. A comparison of how digital and traditional drawing are perceived allows for an understanding of the cognitive level of two seemingly similar, but in fact, different methods of archaeological recording.
Digital drawing, despite its many advantages, such as speed of execution and the ability to easily process images, is not always able to provide as deep an interaction with archaeological artifacts. When using digital drawing, researchers often focus on the technical aspects of the work, which can distract them from critical analysis of the artifacts themselves.
The nature of traditional archaeological drawing makes it an indispensable tool in research, as it fosters a high-quality interaction with artifacts. Visualizing findings through such drawing is a process that combines cognitive and sensory aspects of perception, leading to a deeper understanding of the object. In addition, traditional drawing remains a reliable pedagogical tool; helping new generations of archaeologists not only master technical skills but also develop critical thinking abilities.
Overall, the decline in the use of the «traditional drawing» method, although not yet observed in Ukrainian archaeology, could eventually alter the perception of archaeological finds. The spread of digital recording methods creates a risk that archaeologists may lose important aspects of research that are tied to deep interaction with artifacts. However, digital technologies continue to integrate into modern science, promoting a faster pace of work and access to research results. Combining traditional and digital approaches allows, ensuring both speed and depth of analysis for more comprehensive results.
In conclusion, while modern technologies continue to influence all aspects of science, including archaeology, traditional archaeological drawing remains an important tool. Its preservation and integration with new methods can contribute to the development of archaeological science, maintaining a balance between speed and accuracy, between the demands of modern science and the deep knowledge provided by the traditional approach.
Key words: archaeological drawing, mental models, traditional drawing, digitalization, cognitive archaeology, archaeological knowledge.
The Use of UAV in PAPI System Inspections
Authors: Bryniczka Antoni
Published: December 2024

This article discusses the purpose of aeronautical approach lights for landing and describes the operation of the most popular visual system. In addition, an exemplary schedule describing the periodic verification that the PAPI system must undergo has been presented. The hitherto method of carrying out the verification of indications was discussed, as well as the proposed innovative method of carrying out the verification using an UAV (unmanned aerial vehicle), where its general solution concept was described.
Moreover, the structure and operation of the program responsible for the autonomous light detection of the PAPI system and verification of their indications were discussed. A simulation was carried out using the available recordings, and then the results were described.
Estimating the Determinants of the Passenger Air Transport Recovery After the Crisis Caused by the Covid-19 Pandemic Based on Quantitative Methods
Authors: Cywiński Marcin , Wilczyńska-Strawa Agnieszka
Published: December 2024

For the past several decades, air transport has been developing smoothly, and forecasts were very optimistic. The Covid-19 pandemic set this development back a minimum of two decades. According to the black swan theory, this is not bad news but a stimulus for a change. Every crisis causes improvements in economic processes. The pandemic has forced every business entity present in the market to learn lessons and implement new solutions to help overcome future crises, the occurrence of which seems inevitable. This article  attempts to estimate economic parameters, which are best correlated with the structure of the airline industry operation in Poland, and thus answers questions about the scope of macroeconomic decisions necessary to be taken to rebuild the volume of checked-in passengers in Polish air transport.
Alternative Security of the Combat Readiness Recovery Using 3D Printing and Reverse Engineering
Authors: Kowalski Rafał , Augustyn Sławomir
Published: December 2024

Disrupting spare parts supply chains can harm the smooth running of an organization. In the case of military vehicles, weapons or other types of equipment used on the battlefield, this is a serious threat that may result in the inability to continue some tactical operations. An ad hoc way to maintain the ability to take action while the appropriate spare parts are delivered and to improve damaged devices may be to produce the damaged components locally. Such a temporary solution is possible for relatively simple elements whose structure, mechanical properties and principle of operation can be determined on a reverse engineering basis. This article describes the concept of alternative solutions for temporarily repairing damaged devices by producing spare parts in mobile specialized production subunits. This paper characterizes the types of 3D printing, contemporary examples of use in foreign armies, priorities of international alliances related to 3D printing, and a case study of repairing an unmanned aircraft by means of 3D printing. Using the experience and knowledge of foreign armies, adapting the possibilities of 3D printing applications to one's own needs, defining legal regulations and creating properly equipped subunits makes it possible to implement the presented concept. Creating conditions for implementing the described concept facilitates the production of a suitable product range in peace, crisis or conflict situations, which may significantly contribute to increasing the level of readiness of the national defense systems.
Positioning of Logistic Resources by the Global Navigation Satellite System (GNSS) for Securing Combat Operations
Authors: Augustyn Sławomir
Published: December 2024

This publication presents the possible use of the Global Navigation Satellite System (GNSS) for securing logistics supply chains during combat operations. The study's main purpose is to present how positioning conducted by the GNSS can be an element of military logistics assets support in the logistics chain delivery process. To achieve the stated goal of the research, the following research problem has to be defined: How does the positioning of logistics assets by the (GNSS) affect the security of combat operations?
Specific research problems were identified for the research problems:

What is the essence of using a satellite GNSS for military logistics?
What are the effects of using a satellite GNSS in securing combat operations?

Participants in the research were experts responsible for implementing innovative technologies from the space industry into the GNSS, while the GNSS was the subject of the research. The research hypothesis set in this paper is as follows: The use of the GNSS as satellite system affects the efficiency of the optimization of the logistics supply chain, increased troop safety and increasing allied forces interoperability.
An Ishikawa diagram and GNSS system reliability indicators were used to analyze of the specific problem in detail. This publication was based on doctrinal documents such as: "Doctrine of the Land Forces" DD-4.2, "Logistics Doctrine of the Armed Forces of the Republic of Poland" D-4 (B) version 2.
For the purposes of analyzing the GNSS, information was drawn from "GNSS Technology and its Application in Implementation and Control Measurements" and a publication entitled "Air transport supported by Global Navigation Satellite System (GNSS) in the social security aspect - SARS - Cov-2, Covid-19 pandemic". An additional analysis and evaluation of the logistics supply chain and making relevant conclusions that can influence the further development of this system.
Estimating the Vulnerability of Aviation Operational Stages to Adverse Incidents Based on Civil Aviation Incidents
Authors: Gill Adrian , Kobaszyńska-Twardowska Anna
Published: December 2024

Many safety management processes are conducted using vulnerability measures. It was assumed that such a measure would also be applicable to aviation operational stages, providing an innovative approach to their assessment. However, the research problem generated the necessity of adopting a new definition and mathematical model of vulnerability measure. An analysis of the literature indicated that vulnerability is most commonly a probabilistic measure based on conditional probability, and it can be obtained from information on recorded aviation incidents. The specificity of the analysis area showed that an additional component of vulnerability concerning the diversity of incident causes would need to be considered. This component affects both the severity and frequency of incidents but can also be problematic, for example, in the context of organizing safety systems. Therefore, the aim of this article was to develop and present a mathematical model of the new vulnerability measure for aviation operational stages to adverse incidents in civil aviation systems and to present the results of its estimations. The new model of vulnerability measure presented in this article captures the component related to the diversity of incident causes in the form of an original diversity coefficient based on species diversity measures. The presented measure is not intended to replace the ones currently used but to complement the resources of available safety management tools. The mathematical vulnerability model was prepared to be easily modified if necessary (by adopting other functions), but based on two variables reflecting vulnerability. The results of estimating the vulnerability of selected aviation operational stages according to the developed vulnerability measure show that it is possible to assess these stages in terms of vulnerability to various classes of aviation incidents. The obtained results suggest the potential applicability of this measure to other research problems.
THE ROLE OF TECHNOLOGY AND INNOVATION IN MARKETING TO GENERATION Z
Authors: Rahmat Aldi , Hery Firdaos Ikang , Faizal Muhammad
Published: December 2024

This research aims to analyze and explain the role of technology and innovation in marketing to Generation Z in Sukabumi. The data of this study is MSMEs in Sukabumi City with a population of 31,926 and the sample used in this study is 100 business actors. web.raosoft.com The method in this study used quantitative research, with a data collection method, namely the distribution of questionnaires through Google Forms in the form of statements to respondents and interviews. The analysis method in this study explains that the role of technology and innovation has a positive and significant impact in increasing curiosity in Generation Z, with an impact of 61.2% while other variables influence 38.8%.
How Does Gender Relate to Interpersonal Skills? Exploring Differences in Interpersonal Skills among Primary School Pupils
Authors: Messo Innocent Nasson
Published: December 2024

The current study examined gender differences in interpersonal skills among standard four primary education pupils. Interpersonal skill is a crucial ability that contributes to positive development among primary school pupils. This quantitative research was conducted in the public primary schools of Babati Township Council, Manyara region. The study randomly involved 340 standard four primary school pupils from 17 purposely selected schools (ten boys and ten girls from each school) and their class teachers who were also purposely selected. The assessment tool for pupils was adopted from the MESSY-II (Matson Evaluation of Social Skills with Youngsters –II) to assess interpersonal skills among the selected pupils. T-test was used to test the differences between girls and boys concerning the possession of interpersonal skills. The findings show no significant statistical difference between boys and girls possessing interpersonal skills. This is reflected in both the 'means' and 'p-values'. This study concludes that interpersonal skills are vital for them to prosper academically. Having no significant difference between boys and girls, the study deviates from a body of literature that signifies the difference between the two
Nafasi ya Kazi Teule za Kifasihi Katika Ukuzaji na Uhifadhi wa Mazingira
Authors: Mbuthia Evans Murage
Published: December 2024

Mazingira yana nafasi muhimu sana katika maendeleo na uhai wa viumbe katika sayari yetu. Kutokana na ukweli huu wanamazingira wamekuwa mstari wa mbele katika kupigania mazingira ili yasiangamizwe na mwanadamu. Vita hivi vimeendelezwa na wanasayansi wanaofanya kazi za utafiti katika taasisi tofauti za kisayansi za hapa nchini na za kimataifa. Shughuli hizi aghalabu huendelezwa kwa lugha ya Kiingereza. Makala hii inawasawiri namna ambavyo lugha ya Kiswahili inachangia maswala ya mazingira. Kupitia kwa kazi mbali mbali za kifasihi makala hii itadhihirisha mchango muhimu wa fasihi ya Kiswahili katika uelimishaji wa umma kuhusu mazingira pamoja na ustawishaji na ulinzi wa mazingira. Makala hii itakitwa katika nadharia ya kiekolojia na kurejelea kazi mbali mbali za kubuni ambazo zimesawiri swala la mazingira. Baadhi ya Kazi zitakazotumika katika uchanganuzi wa swala hili ni riwaya za Tikitimaji (Wamitila K.W.), Wimbo Mpya (Mbatia M) na baadhi ya mashairi ya Mberia K. pamoja na hadithi na mashairi kutoka diwani tofauti
Role of Nanotechnology in Combating Ischemic Stroke
Authors: Bikash Medhi  , Sidana Palak
Published: December 2024

Introduction
Stroke is a prevalent neurological disorder caused either by an interruption in the brain's blood supply or a loss of vascular integrity, leading to bleeding within brain tissue, and resulting in neuronal damage.
In vitro Study of Litholytic Activity of Ononis natrix L. Extracts Against Calcium Oxalate Kidney Stones
Authors: Alrifaee Yara , Alkhantib Racha , Obied Amjad
Published: December 2024

Ononis natrix is one of the wild plants from the Fabaceae family. The infusion of the plant is traditionally used for the therapy of urinary tract disorders. Urolithiasis is a deposit of stone components (oxalate, calcium, uric acid, magnesium, cysteine) in the kidneys. The formulation of stones occurs in consecutive stages. Nephrolithiasis is consecration as one of the most common Kidney diseases. Numerous phytomolecules have several functions in the management of urolithiasis. The aim was to investigate the possible litholytic effect of O. natrix extracts against calcium oxalate urinary stones. Stones were collected from urolithiasis patients after surgical procedures. The type of the stones was determined by FTIR spectroscopy, selected of calcium oxalate type, and the experiment was performed by incubating three concentrations (0.5, 1, 2) g/L of aerial parts and root extracts (ethanolic 70% and aqueous) in-vitro with physiological saline (NaCl 9 g/L) for 6 weeks. The results were presented as dissolution rate % compared to positive control (sodium citrate 3 mmol/L) and negative control (physiological saline 9 g/L). The ethanolic 70% extract of the aerial parts in the concentration of 2 g/L showed the highest litholytic activity (47.73% ± 0.66%) at the end of the experiment (week 6) followed by the concentration of 1 g/L (34.81 %± 1.25%) with statistically significant difference (P <0.0001) in comparison with sodium citrate (4.18% ± 2.13%) and physiological saline (1.37% ± 0.22%). 
The results exhibit that the litholytic activity of O. natrix extracts was higher in the aerial parts than the roots, it was also higher in the ethanolic extracts than the aqueous extracts, which is related to their flavonoid content.
Liquisolid Compacts: A Paradigm in Drug Delivery System
Authors: Vohra Payaam , Patil Priya , Mirghal Sudrshan
Published: December 2024

Liquisolid compacts (LSCs) are a fascinating drug delivery technology that offers numerous advantages, particularly for Biopharmaceutical Classification System (BCS) class 2 drugs. In essence, they convert liquid medications into free-flowing, compressible powder forms suitable for tablet production with improved drug release characteristics. Formulation of liquisolid compacts represents a valuable strategy for overcoming solubility challenges, ultimately contributing to the development of an effective and patient-friendly drug delivery system.
Copper Oxide Nanoparticles: Synthesis from Citrus Fruits and Coconut Coir and their Antimicrobial Activity
Authors: Pathak Ashima , Raturi Sonali , Sharma Shivani , Thakur Neetu
Published: December 2024

Background: nanotechnology has been one of the most active research fields in present times. 
Methods: The copper oxide (CuO) nanoparticles (NP) were synthesised from aqueous extracts of coconut coir and citrus fruits (lemons, oranges, and tangerines).
Results: The characterization of nanoparticles was done by UV/Vis and FT-IR spectroscopy. These were examined for their activity against E. coli (gram-negative) and Bacillus species (gram-positive). The highest activity was observed at a maximum dose of 200 mg/ml. In all four samples (different dilutions), both strains exhibited a moderate zone of inhibition compared to their respective controls. Also, the zone of inhibition increased with increasing CuO NP concentrations from 100mg/ml to 200mg/ml for both E. coli as well as Bacillus sp. In addition, while comparing citrus fruits, the zone of inhibition for tangerine CuO NPs was the highest in both bacterial species. However, in comparison with the nanoparticles synthesised using citrus fruits, the zone of inhibition obtained using coconut nanoparticles showed intermediate results against E. coli and Bacillus sp.
Conclusion: The copper oxide nanoparticles obtained from the citrus fruits and coconut coir were found to have good antibacterial potential.
Effect of Combination of Alcoholic Extract of Zingiber Officinale (AEZO) and Hydroalcoholic Extract of Brassica Oleracea (HAEBO) on Papain Induced Osteoarthritis in Wistar Rats
Authors: Karwa Pawan , Kamble Pooja , Jarare Surabhi , V Addepalli , Undale Vaishali , Shelar Shubhangi
Published: December 2024

Background: The “degenerative joint disease” i.e. Osteoarthritis (OA) is very common nowadays, which affects generally the knee joints. Osteoarthritis occurs in all the synovial joints of the hand, spine, wrist, hip, knee, and ankles. While we are focusing on the current Indian scenario, it was found that the prevalence rate of osteoarthritis ranges from 22-39 percent. Overall, it often affects both males and females after the age of 45. It affects more than 500 million people globally. Age, weight, gender, joint damage, and heredity were additional risk factors for OA. Osteoarthritis causes pain, functional limitation, and deterioration. Herbal remedies can be used to treat such diseases. 
Methods: The alcoholic extract of Zingiber officinale (AEZO) and the hydroalcoholic extract of Brassica oleracea (HAEBO) in 1:1 proportion were evaluated against papain-induced OA. 
Evaluation: The paw volume, blood and liver parameters, serum calcium level, histopathology, and radiology were performed once after the treatment of 28 days with the combination. 
Result: The results of the combination of AEZO and HAEBO-treated groups show that paw volume was reduced but the percentage of paw edema is enhanced. The histological and radiological results also indicated that a mixture of AEZO and HAEBO in 1:1 proportion has anti-osteoarthritic activity in papain-induced osteoarthritis.
Formulation and Evaluation of Bilayer Tablets of Granisetron HCl and Ibuprofen for the Treatment of Migraine
Authors: Pawar Nita , Desai Prapti , Jadhav Kalyani , Shah Pranita , Shrotri Sujata N
Published: December 2024

Background of the Topic: The major purpose of this study was to produce a bilayer pill that contained Granisetron HCl (GSH) and ibuprofen (IBF) in distinct layers to minimize the possibility of adverse drug interactions and maximize the efficacy of both medications when they were combined to treat the symptoms of migraines. In contrast to the IBF layer, the GSH layer was intended to have a more gradual release of its contents. 
Methods: Microcrystalline cellulose, sodium starch glycolate, and croscarmellose sodium were the chemicals used to create the rapid-release layer. Isopropyl alcohol, magnesium stearate, and HPMC K 4M were among the polymers and gums that were used in the process of producing the continuous release layer. First, the fine-tuning process was performed on the tablet's two layers. After that, the layers necessary for quick as well as extended-release were put together. There were no adverse reactions caused by the active components interacting with the excipients. The rate at which a medicine is absorbed into the body may be sped up by using Croscarmellose sodium in a formulation. 
Results:  A combination is given a delayed release influence by the addition of HPMC K 4M. The bilayer tablet forms from the improved (IR-4) batch were found to have strong linearity as shown by the regression coefficient of 0.9773, which is a first-order equation. According to the results, a bilayer pill that has both an increased IR-4 GSH immediate release layer and an SR-5 IBF sustained release layer would be an effective way to treat migraines. 
Conclusion: Bilayer tablets with releasing qualities provide a wide variety of benefits, some of which include the ability to localize medication administration, enhanced absorption, and improved effectiveness.
Retrospective analysis of the clinical efficacy of BuzhongQingli decoction in immunoglobulin A nephropathy exhibiting the dampness-heat due to spleen deficiency syndrome
Authors:   China Academy of Chinese Medical Sciences, Tao Jing , Zhang Zhi-Lin ,   Shanxi University of Chinese Medicine, Liu Ran ,   China Academy of Chinese Medical Sciences, Tan Xiao-Ning ,   China Academy of Chinese Medical Sciences, Li Hao ,   China Academy of Chinese Medical Sciences, Zhao Li-Ming ,   China Academy of Chinese Medical Sciences, Cheng Yu-Rong ,   China Academy of Chinese Medical Sciences, Yu Da-Jun ,   China Academy of Chinese Medical Sciences
Published: December 2024

To investigate the effect of BuzhongQingli Decoction (BZQLT) on the symptoms, hematuria, proteinuria, serum creatinine (SCr) of patients with immunoglobulin A nephropathy (IgAN), exhibiting the dampness-heat due to spleen deficiency syndrome. Methods: Patients with IgAN who were treated with BZQLD over a three-month period between 2022 and 2023, were enrolled in this study. Data collected included TCM syndrome scores, urine red blood cell count/HP, 24-hour urinary protein quantification (24-UTP), SCr before and after treatment. Results:Treatment with BZQLD over three months led to significant reductions in TCM syndrome scores, urine red blood cell count/HP, 24-UTP, and SCr levels in 62 patients. Conclusion: BZQLD effectively reduces the TCM syndrome scores and improves key clinical efficacy indicators in patients with IgAN presenting with the dampness-heat due to spleen deficiency syndrome, demonstrating its substantial clinical efficacy
Deciphering curcumin and piperine's anti-amyloidogenic capabilities using an in silicomethod: A look at ligand-target complex formation
Authors:   King Faisal University Al-Hofuf, Afzal Sheryar
Published: December 2024

Amyloid-β (Aβ) peptides play pivotal role in the pathogenesis of Alzheimer Disease (AD) and exert toxic effects on neurons. Current treatment options available to AD patients, such as AChE inhibitors, only provide symptomatic relief. Dietary phytochemicalsare currently being used as adjuvant therapy to expedite their therapeutic efficacy. This study was designed to investigate potential bioactive compounds of curcumin and piperine as anti-amyloidogenic agents. Molecular docking was applied to conduct screening process in silico to predict the most probable conformation of curcumin and piperine ligand when they bind to Aβ42 peptide. Molecular docking screening showed that curcumin and piperine could bind to Aβ42 peptide with different binding affinities. Curcumin possessed binding affinity to Aβ42 peptide with binding energyof -5.6 kcal/mol while piperine had binding energy of -5.4 kcal/mol. Considering binding affinities, intermolecular interactions with amino acids, hydrogen bonding and hydrophobicity, curcumin emerged as potential lead compound to treat AD.
Marketing Strategies, Experiential Marketing, and Public Relations in Increasing the Number of Tourist Visits
Authors: Maheswari Anak Agung Istri Agung , Ariwangsa Kadek Ryodinero Wahyunanda
Published: December 2024

This research aims to test and analyze the influence of Marketing Strategy, Experiential Marketing and Public Relations in increasing the number of visits. This research was conducted at the Muntig Siokan Inspiration Park with a research sample of 100 respondents taken using the Slovin formula. All data obtained from the questionnaire distribution is suitable for use, then analyzed using multiple linear regression, hypothesis testing (t test and f test). The results of the research show that (1) Marketing Strategy has a positive and significant effect in increasing the number of visits to the Muntig Siokan Inspiration Park, so that the more Marketing Strategy increases, the more visits to the Muntig Siokan Inspiration Park (2) Experiential Marketing has a positive and significant effect in increasing the number of visits to the Muntig Siokan Inspiration Park so that the more Experiential Marketing increases,  the more visits to the Muntig Siokan Inspiration Park (3) Public Relations has a positive and significant effect in increasing the number of visits to the Muntig Siokan Inspiration Park, so that the more Public Relations increases, the more the number increases. visit to the Muntig Siokan Inspiration Park. (4) Marketing Strategy, Experiential Marketing and Public Relations have a positive and significant effect in increasing the number of visits to the Muntig Siokan Inspiration Park.
Primary Industries Education Foundation Australia (PIEFA) Storm and Flood Industry Recovery Program: Evaluation report
Authors: Van Der Zant Tamara , Dix Katherine
Published: December 2024

Despite the growing diversity of careers in Primary Industries, young peoples’ pursuit of agricultural careers is often hampered by outdated perceptions of the sector and its opportunities. As Primary Industries adapt to the threat of natural disasters by turning to scientific and technological solutions, a diverse, highly skilled workforce will be required. In the wake of the devastating impacts of storm and floods in early 2021 across New South Wales, the Storm and Flood Industry Recovery Program (SFIRP): Creating resilience through empowering school curriculums about primary industries careers project was developed. To aid the long-term recovery and resilience of the NSW agriculture industry, Primary Industries Education Foundation Australia (PIEFA) was tasked to design and provide educational opportunities for promoting studies of food, fibre and agriculture and associated careers. The program aimed to inspire students in NSW to pursue career pathways in Primary Industries. Accordingly, the SFIRP has endeavoured to support industry recovery by challenging industry misconceptions and equipping teachers and careers advisors to educate students about opportunities to post-school pathways and careers in agriculture. An independent evaluation of SFIRP was undertaken by the Australian Council for Educational Research (ACER) and is presented in this report.
Pelatihan Pembuatan Nugget Tempe pada Kelompok “Generasi Z” Desa Cokrowati Kecamatan Todanan Kabupaten Blora
Authors: Nur'aini Siti , Puspitasari Titik
Published: December 2024

Tempe merupakan lauk utama yang kaya akan nutrisi yang termasuk komoditi besar Indonesia, inovasi pengolahan tempe sangat beragam, mulai, tempe goreng, kripik, bacem, dan aneka olahan lainya yang tentunya terdapat kandungan gizi yang sangat baik untuk kesehatan. Untuk meningkatkan variasiolahan tempe tanpa mengurangi kandungan gizi maka dibuatlah inovasi nugget Tempe yang tentunya digemari berbagai kalangan mulai anak- anak sampai oaramg tua. Pelatihan ini bertujuan untuk  meningkatkan ketrampilan generasi muda dalam mengolah bahan pangan lokal yang bernilai tambah baik dari segi nutrisi dan nilai jual. Selain itu pelatihan ini dirancang untuk memberikan wawasan dan pengalaman praktis dalam memproduksi nugget tempe yang sehat dan bernutrisi. Metode pelatihan meliputi penyampaian materi, demonstrasi langsung, serta praktik pembuatan mulai dari pemilihan bahan baku, pengolahan, pembentukan, penggorengan, hingga pengemasan produk. Peserta aktif terlibat dalam setiap tahap pelatihan, yang juga dilengkapi dengan sesi diskusi untuk mengeksplorasi potensi bisnis dari produk olahan ini. Hasil pelatihan menunjukkan bahwa peserta dapat memahami dan mengaplikasikan teknik yang diajarkan, serta memiliki motivasi untuk mengembangkan usaha berbasis tempe di desa mereka. Dengan demikian, pelatihan ini diharapkan dapat mendorong munculnya enterpreneur muda dan memperluas diversifikasi produk pangan lokal di Desa Cokrowati.
Eine innovative Methode zur Förderung der Lesemotivation von DaF-Lehramtsstudierenden im Literaturunterricht: Bookdating
Authors: Gündoğdu Tolga , Kul Aylin Nadine
Published: December 2024

Ausgehend von der großen Bedeutung der Lesefreude und Lesemotivation für die Verstehensprozesse bei der Rezeption literarischer Texte und dem großen Stellenwert des Lesens sowie literarischer Texte für DaF-Lehramtsstudierende werden im Rahmen dieses Artikels die möglichen Vorteile einer innovativen Methode, des sogenannten Bookdating, zur Förderung der Lesemotivation bei DaF-Lehramtsstudierenden analysiert. Der Begriff Bookdating bezeichnet eine didaktische Vorgehensweise, deren Ziel es ist, Individuen zur Lektüre zu motivieren, indem in kurzen Gesprächen von jeweils 5–10 Minuten der Inhalt eines Buches erörtert wird. In dieser explorativen Studie, die zugleich Hinweise zur Planung und praktischen Durchführung einer Bookdating-Veranstaltung bietet, geht es primär darum, die potentiellen Auswirkungen des Bookdating auf das Leseverhalten und die Einstellung zum Lesen von DaF-Lehramtsstudierenden zu diskutieren und Impulse für den Einsatz dieser innovativen Methode an der DaF-Lehrerausbildung zu geben. Außerdem mag dieser Beitrag als Anreiz dafür genommen werden, empirische Studien zur Methode des Bookdating in Gang zu setzen, um die Forschungen zur Lesefreude und Lesemotivation zu bereichern. Die gesichteten Vorteile, die diese Methode mit sich bringt, mögen zugleich zu ihrer Anwendung in den anderen Philologien, sprachlichen Lehramtsstudiengängen oder gar im schulischen Sprachunterricht anregen.
Psycho-Discourse Analysis of Procrastination in Biblical and Quranic Verses
Authors: Abed Safa Naji , AlMamoory Salih Mahdi Adai
Published: December 2024

The study attempts to analyze procrastination verses in religious texts from psycho-discourse perspectives as psychological factors, discourse acts, transitivity, and discursive strategies. Twenty extracts are analyzed by qualitative methods. The results show different psychological features as emotional valence and arousal. They also display three discourse acts like informative, elicitation, and directives. The study results with different processes of transitivity as mental, material, behavioral, etc. It also displays different psychological strategies as hyperbole, norm violations, and negative comparison.