bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimization of Fermentation Process for Apricot Vinegar
Authors:   College of Agriculture and Forestry Science and Technology, Hebei North University, Zhangjiakou 075000, China., Cao Ximin , Lv Aizhi ,   College of Agriculture and Forestry Science and Technology, Hebei North University, Zhangjiakou 075000, China.
Published: August 2023

To study the optimal fermentation conditions of Prunus armeniaca L. (apricot), single factor experiments and orthogonal experiments were implemented. The experimental results demonstrate that the optimum alcoholic fermentation conditions are: sugar degree a 9%, inoculation quantity of yeast at 0.7%, fermentation temperature at 30 ºC. The alcohol degree could reach 7.56%; the optimum acetic fermentation conditions are: alcohol degree at 7%, inoculation quantity of acetic acid bacillus at 0.8%, fermentation temperature at 32 ºC, fermentation time at 7 days, and the total acid content could be obtained as 6.78 g/100 mL. Under such conditions, the fruit vinegar has rich Prunus armeniaca L. flavor and pure taste.
Using Spinal Anesthesia and a Fracture Table for Closed Reduction of an Obturator Foramen Hip Dislocation
Authors: Carlson Bradley A. , Riggs Thomas P. , Douglas Michael S. , Woodard David R. , Syed Hasan M.
Published: August 2023

Case:

A 37-year-old man with a right obturator foramen hip dislocation underwent closed reduction under spinal anesthesia with the use of a fracture traction table.

Conclusion:

This novel technique provides surgeons and anesthesiologists an alternative method of treating obturator foramen hip dislocations that provides a more controlled reduction and less need for assistants.
The Development of Startup Coop in Indonesia: An Overview Maqashid al-Sharia
Authors: Jayusman Jayusman , Efrinaldi Efrinaldi , Rachman Muhammad Aulia , Jayus Muhammad
Published: August 2023

This paper uses the juridical-philosophical method and conceptual approach to develop regulations for cooperative-based startup companies (startup coop) in Indonesia from the perspective of positive law and maqāsid al-Sharīa. This study concludes that the issue of startup coop from the maqashid perspective is considered not contrary to Islamic values, the principles of muamalah, and in harmony with the objectives of the law. Startup Coop is oriented towards creative innovation based on the value of brotherhood and kinship. In addition, startup coops also aim to absorb productive labor and develop human resources from among the younger generation in creative business development. This research contributes to optimizing creative and innovative human resources in line with maqashid ideal goals.
Impact of Implementation of Halal Tourism in West Nusa Tenggara Province: Maqāṣid al-Sharīa Perspective
Authors: Rachman Abdul , Sangare Bilaly
Published: August 2023

This study aims to analyze the benefits and harms of implementing Halal Tourism in West Nusa Tenggara Province from the perspective of maqāṣid sharīa. This study uses a qualitative method with a phenomenological approach and holistic Fiqh theory. The phenomenological approach is carried out to analyze social phenomena after implementing halal tourism. The Fiqh theory approach focuses more on Islamic law within the scope of maqāṣid al-sharīa. The results of the study state that the impact of halal tourism in West Nusa Tenggara Province on the community, tourists, and the government is dominated by benefit rather than benefit. The impact of halal tourism from the perspective of maqāṣid al-sharīa can be seen from indicators in maintaining religion (hifdzu sd-din) in halal tourism, namely the convenience for tourists with the availability of prayer facilities in each destination. In protecting life (hide an-nafs), local governments are increasing the number of halal certifications, localization of Halal tourism destinations, and restrictions on alcoholic beverages. In maintaining reason (hifdz al-'aql), the role of the community in developing halal tourism is carried out through Islamic boarding schools. In protecting offspring (hifdz an-nasl), tourists and the public can use several sharia-compliant lodging accommodations such as the Syariah Motel and the Grand Madani Syariah Hotel. Meanwhile, in protecting assets (hifdz al-maal), the community and government provide halal businesses and Islamic financial institutions such as Bank NTB Syariah. The contribution of this article is a guide for the government in making policies and regulations for the implementation of halal tourism in Indonesia.
Regulation of Halal Product Certification in The Dynamics of Indonesian Legal Politics
Authors: Mawardi Warsis , Ichsan Muchammad
Published: August 2023

The purpose of this study is to explore how the regulation of halal product certification in the dynamics of Indonesian legal politics, especially since the existence of Law No. 8 of 1999 concerning Consumer Protection to the presence of Law No. 33 of 2014 concerning Halal Product Guarantee. UUPK as the basis for LP POM MUI to carry out halal product certification as well as halal labeling using the MUI halal logo. The presence of the JPH Law has an impact on policy changes and a new governance paradigm which has implications for causing a tug of war between MUI, the government and the legislature. By using normative juridical research topilogy and qualitative data analysis, it can be concluded: First, the Certification regulation has dynamics, especially during the discussion of the JPH Bill, until there is an interesting dance between MUI, the Government including the DPR faction faction regarding the institution authorized to implement certification, including whether or not it is mandatory for business actors to carry out certification. Second, halal certification which was originally carried out by MUI through a detailed examination by LPPOM MUI, after the decision of the JPH Law, the authority to carry out certification is carried out by BPJPH under the auspices of the Ministry of Religion by still involving MUI but using a new halal label / logo.
Geostatistical mapping to delineate areas of soil-transmitted helminthiasis persistence in Cameroon: a protocol for systematic review and meta-analysis
Authors: Djeunga Hugues C. Nana , Foka-Sindze Antonia , Sumo Laurentine , Djune-Yemeli Linda , Okoyo Collins , Niamsi-Emalio Yannick , Nguefack-Tsague Georges , Njiokou Flobert , Kamgno Joseph
Published: August 2023

Background
Soil-transmitted helminths (STH) remain the most common parasites of the gastrointestinal tract in Cameroon. However, despite all efforts put in place for their control, their prevalence remains unexpectedly high in some parts of the country. This systematic review aims to identify and delineate areas of high transmission (hotspots) of STH in Cameroon. The goal is to consolidate existing data on STH epidemiology and control in Cameroon in order to develop optimal control strategies to achieve the World Health Organization (WHO) goal of elimination as public health problem by 2030 as defined in the new NTD roadmap.
Methods
PubMed/MEDLINE, Google Scholar, Embase, African Journals Online, Africa Index Medicus, Global Index Medicus, Web of Knowledge and ISI web of science will be searched to identify articles, regardless of the language of publication. The Medical Subject Headings (MeSH), Embase Thesaurus (Emtree) and text words will be used for the search strategy. Unpublished and published data and resources (reports, datasets) will be requested by contacting authors and stakeholders involved in research and control of STH in Cameroon, especially the National Program for the Control of Schistosomiasis and Intestinal Helminthiasis (PNLSHI), the Neglected Tropical Diseases Coordination Unit of the Cameroon Ministry of Public Health, and the Expanded Special Project for Elimination of Neglected Tropical Diseases (ESPEN) of the WHO/AFRO. Random-effects meta-analysis and meta-regression will be used to identify covariates influencing the estimates with the aim of identifying models that best predict the variability of effect sizes. Publication bias will be assessed using funnel plots and Egger’s regression asymmetry test.
Discussion
This study will provide policy makers and the neglected tropical diseases (NTD) community, especially the National Control Program (PNLSHI), with up-to-date consolidated data on STH trends, prevalence and intensity, and the impact of the control strategies over time, and help to guide the paradigm shift from elimination of STH as a public health concern to transmission interruption.
Systematic review registration:
This protocol will be registered with the International Prospective Register of Systematic Reviews (PROSPERO).
Low Complexity Physical Layer Cell Identification for 5G New Radio
Authors: Li Chi-Min , Chiu Ching-Wang , Wang Pao-Jen
Published: August 2023

In the fifth generation (5G) new radio (NR), systems can be operated at the sub-6GHz or millimeter wave spectrums. Due to the serious fading characteristics of the millimeter waves, third generation partnership project (3GPP) doubles the number of the physical layer cell identifiers from 504 of the conventional fourth generation (4G) long term evolution (LTE) to 1008 for the 5G NR. Therefore, the required calculations at the user equipment (UE) to identify the serving base stations become more and more complicated since that UE must conduct the identification via synchronization signal block (SSB) periodically. Therefore, it is an important issue to reduce the identification calculations for the purposes of green communications or low latency applications. In the paper, a low complexity algorithm of cell identification using the secondary synchronization signal grouping and correlation shortening is proposed to reduce the required computations of the physical cell identification. Both simulations and experiments were conducted via the software defined radio (SDR) to evaluate the performances. According to the results, it can be shown that the proposed low complexity algorithm can complete the cell identification correctly with the computational reduction advantage up to 90% than the compared literary cell identification methods.
Voice Based Email System for the Visually Challenged
Authors: Prakash Satya , Agrawal Kartikey , Dosaj Siddharth , Singh Shatakshi
Published: August 2023

In today's digital world, email is a crucial form of communication, but it can be difficult for those who are blind or visually impaired to access and use it. The idea of a voice-based email system created exclusively for those with visual impairments is presented in this abstract. The objective is to provide a welcoming atmosphere that enables people who are blind or visually impaired to use computers on their own to send and receive emails.
The suggested solution has cutting-edge components designed with visually impaired users in mind. By integrating a screen reader, users may convert text into voice and interact with the email interface aloud. Users may create emails using their voice thanks to reliable speech recognition technology that properly converts spoken words into written text. To continually develop the system and adapt it to unique tastes and needs, user input and customization options are included.
Assessment of the effect of heat processing on vitamin composition of selectedstaple green leafy vegetables in Nigeria
Authors: Sunday Adeniyi Adegoke , Peter Agbugui Agbomire , Saheed Solola Olanrewaju , Jacob Oyeku Sunday
Published: August 2023

This study assessed the effect of the steamed and boiling cooking methods on the vitamin content of six staple green vegetables in Nigeria. Vitamin levels in fresh, steamed and boiled leafy vegetables were determined using spectrophotometric and titrimetric methods. The results of vitamin analysis showed that fresh vegetable of Amaranthus hybridus contained the largest amount of ascorbic acid, thiamin and niacin (358.40 mg/100 g), (0.09 mg/100 g) and (0.08 mg/100 g) respectively, while Talinum triangulare had the highest level of riboflavin (0.18 mg/100 g). The steamed Amaranthus hybridus contained the highest levels of ascorbic acid, thiamin and niacin (322.56 mg/100 g), (0.08 mg/100 g) and (0.73 mg/100 g) respectively, while Talinum triangulare had the highest quantity of riboflavin (0.16 mg/100 g). The boiled Amaranthus hybridus had the highest amount of ascorbic acid, thiamin and niacin (197.12 mg/100 g), (0.05 mg/100 g) and (0.41 mg/100 g) respectively, whereas the Talinum triangulare had the highest level of riboflavin (0.09 mg/100 g). The percentage of vitamin loss in steamed leafy vegetables varies from 9 to 11%, 9 to 17%, 9 to 13% and 9 to 12% in ascorbic acid, thiamin, riboflavin and niacin respectively. Almost 50% of the essential vitamins were lost in boiled leafy vegetables. The results revealed that vegetables could be an improved source of some important vitamins that can help humans meet their nutritional needs. According to vegetable processing results, we advised that steamed vegetables be regularly consumed rather than boiled vegetables, which prevents hypertension-related disorders.
Improving Marketing Strategies using Data Mining and Decision Support Systems in E-commerce Platforms
Authors: Huang Junliang
Published: August 2023

Growing businesses need e-commerce systems; marketers must help analyze data and make decisions. Data mining and decision support systems optimize marketing campaigns by analyzing customer preferences and purchase habits. With this combination, personalization, trend spotting, client segmentation, and cross-selling improve customer satisfaction, conversion rates, and Return on Investment (ROI). This paper aims to conduct a thorough study on the optimization of e-commerce marketing strategy based on data mining and decision support systems to solve the issues of high-cost investment in e-commerce platforms, low efficiency of online marketing, and improve the sales performance of e-commerce platforms. First, a Browser / Server mode (B/S) architecture based on e-commerce marketing system is built. The system is broken down into interface, functional, and support layers. The support layer includes multiple system interfaces to achieve data exchange across various functions inside the network marketing channel. The functional layer includes network marketing, service monitoring and management, basic information management, and other modules. Subsequently, the e-commerce platform utilizes the decision tree algorithm to optimize its online marketing strategy. This involves filtering the data available on the platform and subsequently computing the data structure and dissimilarity matrix. The ultimate objective is to determine the closest data class distance. The decision tree data mining algorithm is utilized to optimize the online marketing strategy of the e-commerce platform. The method proposed in this paper has been validated through experimental verification and has demonstrated a robust data throughput capacity. It has also been shown to effectively enhance the efficiency of online marketing. Furthermore, the system designed in this paper has the potential to enhance the economic benefits of e-commerce platforms.
A novel floating piezoelectric energy harvesting from water waves: fully-coupled simulation
Authors: Khorramdarreh Erfan Rajabi , Mohammadi Mohammad Mostafa , Ghazanfarian Jafar
Published: August 2023

A fully-coupled-fluid-structure-piezoelectric model is presented based on the finite element method that is capable of modeling piezoelectric harvesters in the presence of free-surface flow and floating lightweight harvesters with arbitrary movements. The Navier-Stokes equations and the phase-field method are employed to describe the free-surface waves. Equations of the conservation of linear momentum in company with the piezoelectric constitutive relations in the strain-charge form are utilized to obtain solid deformation and the electric field intensity. According to the results, attaching mass to the tip of the beam leads to 13.5% rise in the output voltage compared to the state without the attached mass. Another studied factor was the influence of the load resistance on voltage and the output power. The generated voltage grows along with the load resistance until it reaches a constant value. However, the power has an optimum load resistance that is 2.61 times higher than the reference state. The beam's inclination is significant in effectively exploiting water waves due to raising the root mean square (RMS) value of the voltage by 89.53% at an angle of 40 degrees relative to the vertical state. By altering the thickness of the beam from 1 mm to the value of 1.5 mm, the RMS voltage exhibits a considerable upward change of 66%. By increasing the length of the cantilever beam connected to the buoyant structure, and therefore, the indentation of the beam in the water, the output voltage grows, such that a beam with the length of 25 cm shows a 2.92 times increase in the output voltage relative to the beam with a length of 15 cm.
An Important Cheese in Turkish Cuisine: A Research on PGI-Registered Erzurum String Cheese
Authors: DENK ERKAN UYGULAMA
Published: August 2023

Cheese communicates the identity and culture of the regions where they are produced to consumers. This includes the origin of the milk used, pastures greened with aromatic herbs and natural scenery, cheese producers, traditional production methods, and consumption rituals. This vast structure is, in fact, closely related to cheese-focused tourism. In addition, the industrial property rights geographical indication (GI) provides quality assurance to consumers regarding the product it has registered and protected and offers economical, social, and environmental benefits to the region where production is made. The purpose of the current study is to reveal the importance of the GI-registered Erzurum string cheese, one of the essential tastes of Erzurum cuisine, to contribute to the importance of it in the local cuisine, to review the production stages according to the registration document and to develop recommendations for transferring it to future generations. Erzurum string cheese is a type of cheese produced in the Eastern Anatolia Region of Turkey. It was registered with the particular mark in 2009 and enjoyed nationwide.
Top-down effects of intraspecific predator behavioral variation
Authors: Lichtenstein James L.L. , McEwen Brendan L. , Primavera Skylar D. , Lenihan Thomas , Wood Zoe M. , Carson Walter P. , Costa-Pereira Raul
Published: August 2023

Among-individual variation in predator traits is ubiquitous in nature. However, the role of intraspecific trait variation in trophic dynamics has been seldom considered in community ecology. This has left unexplored a) to what degree does among-individual variation in predator traits regulate prey populations and b) to what degree do these effects vary spatially. We address these questions by examining how predator among-individual variation in functional traits shapes communities across habitats of varying structural complexity, in field conditions for the first time. We manipulated Chinese mantis (Tenodera sinensis) density and trait variability in experimental patches of old fields with varying habitat complexity and quantified the impacts on lower trophic levels, specifically prey and plant biomass. Our mantis groups thus contrasted in density (six or twelve individuals) and levels of variation in a key behavioral trait, activity level (movement on an open field). Our metric of habitat complexity was the density of plant material. In complex habitats and at high mantis densities, behaviorally variable groups decreased prey biomass by 35.1%, while at low densities, low levels of behavioral trait variability decreased arthropod biomass by 27.1%. Behavioral variability also changed prey community composition. Our results are among the first to demonstrate that among-individual trait variation can shape open species-rich prey communities. Moreover, these effects depend on both predator density and habitat complexity. Incorporating this important facet of ecological diversity revealed normally unnoticed effects of functional traits on the structure and function of food webs.
Design of an digital management system for museum collections based on RFID and improved GIS technology
Authors: Zhang LingYu
Published: August 2023

In recent years, the amalgamation of radio frequency identification (RFID) technology and deep learning has facilitated the convergence of objects and the Internet, thereby enabling seamless identification, management, and control. Collections constitute a pivotal aspect of a museum's operations, and the scientific oversight of collections serves as the foundation for the advancement of other museum endeavors. In order to augment the precision and contemporaneous monitoring of the storage environment for museum collections, alleviate the workload burden on museum personnel, and enhance overall operational efficiency, this study devises an electronic management system for museum collections that integrates RFID technology with geographical information systems. Within our geoinformation technology framework, we have integrated an enhanced LANDMARC algorithm, enabling us to render the collection's whereabouts visually by portraying real-time location information of the accessions on electronic maps specially crafted for the museum. Simultaneously, we employ RFID technology to promptly identify the real-time location of staff members and evaluate their inspection duties. By harnessing the potential of these two technologies, we have succeeded in ameliorating the efficacy of real-time collection management and fostering intelligent collections management when juxtaposed with existing systems. This research endeavors to propel the progressive evolution of RFID technology within the realm of item identification and location.
Evaluation of new generation immune-systemic inflammation markers to predict of urine culture growth in urinary tract infection in children
Authors: Elgormus Yusuf , Okuyan Omer , Dumur Seyma , Sayili Ugurcan , Cetinok Hurriyet , Uzun Hafize
Published: August 2023

Objective
Systemic inflammation has been implicated in urinary tract infection (UTI) development and progression. Accordingly, the aim of this study was to determine whether the white blood cell (WBC), the C-reactive protein (CRP), the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and the systemic immune-inflammation index (SII) are useful markers to predict of urine culture growth in children with UTI. Secondly, it was also to evaluate the prevalence of UTI pathogens, antibiotic resistance patterns, and empirical treatment options in children diagnosed with UTI by laboratory and clinical findings.
Method
Study population comprised 413 cases (positive urine culture) and 318 cases (negative urine culture) with UTI.
Results
There was no statistically significant difference in the medians of hemoglobin (HGB), hematocrit (HCT) and platelet (PLT) between the negative and positive culture groups. The median of monocytes, WBC, NLR, SII and CRP of the patients have positive urine culture was statistically significantly higher than the negative urine culture group. The AUC value was 0.747 (0.710–0.784) for CRP with a cut-off value of 3.2, the sensitivity is 56.4% and specificity is 98.4% in terms of UTI. The AUC value was 0.733 (0.697–0.769) for SII with a cut off value of 600, the sensitivity is 58.4% and the specificity is 83.0%. The AUC value was 0.732 (0.697–0.769) for NLR with a cut off value of 2, the sensitivity is 57.4% and the specificity is 81.1%.
Conclusion
WBC, CRP, NLR, PLR and SII may a useful independent diagnostic or complementary marker for disease in children diagnosed with UTI have positive urine culture. E. coli was the most common causative agent, the most used antibiotic is cephalosporin, high resistance to cefuroxime, trimethoprim-sulfamethoxazole (TMP-SMX), cefixime, ampicillin, and ceftriaxone was detected in all agents of UTIs in childhood in our center.
The Effects of Cognitive Leisure Activities on Frailty Transitions in Older Adults in China: A CHARLS-Based Longitudinal Study
Authors: Sheng Kai , Chen Hao , Qu Xianguo
Published: August 2023

Background
In an effort to identify factors associated with frailty transitions that trigger a significant difference in preventing and postponing the progression of frailty, questions regarding the role of cognitive leisure activities on various aspects of older adults' health were raised. However, the relationship between cognitive leisure activities and frailty transitions has rarely been studied.
Methods
A total of 5367 older Chinese adults aged over 60 years from the China Health and Retirement Longitudinal Study (CHARLS) were selected as participants. The 2nd wave of the CHARLS in 2013 was selected as the baseline, and sociodemographic and health-related status baseline data were collected. The FRAIL Scale was used to measure frailty, while cognitive leisure activities were measured by the Cognitive Leisure Activity Index (CLAI) scores, which consisted of playing mahjong or cards, stock investment, and using the internet. After two years of follow-up, frailty transition from baseline was assessed at the 3rd wave of the CHARLS in 2015. Ordinal logistic regression analysis was used to examine the relationship between cognitive leisure activities and frailty transitions.
Results
During the two-year follow-up of 5367 participants, the prevalence of frailty that improved, remained the same and worsened was 17.8% (957/5367), 57.5% (3084/5367) and 24.7% (1326/5367), respectively. Among all participants, 79.7% (4276/5367), 19.6% (1054/5367), and 0.7% (37/5367) had CLAI scores of 0, 1, and 2 to 3, respectively. In the univariate analysis, there was a statistically significant association between a score of 2 to 3 on the Cognitive Leisure Activity Index and frailty transitions (odds ratio [OR] = 1.93, 95% CI 0.03 to 1.29, p = .04), while all other covariates were not significantly different across the three groups. After adjusting for covariates, participants with more cognitive leisure activities had a higher risk of frailty improvement than those without cognitive leisure activities (odds ratio [OR] = 1.99, 95% CI 1.05 to 3.76, p = .04).
Conclusions
Cognitive leisure activities were positively associated with the risk of frailty improvement in older adults, mainly when participating in multiple such activities. Older adults may be encouraged to participate in a wide variety of cognitive leisure activities to promote healthy aging.
Hospitalized children with COVID-19 infection during large outbreak of SARS-CoV-2 Omicron strain: a retrospective study in Chaozhou, Guangdong, China
Authors: Lin Fen , Chen Man-Tong , Zhang Lin , Xie He , Yang Zhe , Huang Bin , Wu Jian-Peng , Lin Wei-Hao , Yang Li-Ye
Published: August 2023

Objective
We aimed to investigate the clinical findings of hospitalized pediatric COVID-19 patients by the end of 2022.
Method
All confirmed children with COVID-19 infection admitted into Chaozhou Central Hospital from December 19, 2022 to February 1, 2023 were included. Detailed clinical data of those children were evaluated retrospectively.
Results
A total of 286 children, ranging in age from 1 month to 13 years old, were diagnosed with SARS-CoV-2 infection. Among these cases, 138 (48.3%) were categorized as mild, 126 (44.0%) as moderate, and 22 (7.7%) as severe/critical. Symptoms varied among the children and included fever, upper respiratory tract symptoms, convulsions, sore throat, poor appetite, dyspnea, and gastrointestinal symptoms. Notably, febrile convulsions were observed in 96 (33.6%) patients, while acute laryngitis was documented in 50 (17.5%) cases. Among the severe/critical patients, eight developed multisystem inflammatory syndrome in children (MIS-C), and tragically, one patient's condition worsened and resulted in death. Furthermore, MRI scans revealed abnormal brain signals in six severe/critical patients. The severe/critical group also exhibited more pronounced laboratory abnormalities, including decreased hemoglobin and elevated ALT, AST, LDH, and CK levels.
Conclusions
Febrile convulsions and acute laryngitis are frequently observed in children diagnosed with SARS-CoV-2 Omicron infection. Moreover, multisystem inflammatory syndrome in children (MIS-C) and abnormal neuroimaging appear to be relatively common phenomena in severe/critical cases.
Effect of salinity on some enzymatic and non-enzymatic antioxidants of Asada-Halliwell pathway in P. cineraria and P. juliflora
Authors: Sharma Monika , Dinesh Rachana , Sen Seema
Published: August 2023

Increased level of antioxidants and enzymatic activity protects the plants from oxidative damage under stress conditions. In the present study antioxidants involved in the ascorbate–glutathione (ASC–GSH) cycle (APX, GR, ascorbate and dehydroascorbate) were investigated under salt stress in two species of genus Prosopis (P. cineraria and P. juliflora). Both these species are economically very important in arid and semi-arid regions of Rajasthan. For the experimentation one-week-old seedling were treated with different salt concentrations ranging from 0 to 200 mM (0, 25, 50, 75, 100, 150 and 200). The leaves were harvested after 15 and 30 days. The ascorbate content of both the species increased under salt stress. But dehydroascorbate content decrease. The activity of enzymes ascorbate peroxidase (APX) and glutathione reductase (GR) were also found to be increased under salt stress. The increase was comparatively more prominent in P. juliflora which indicates the upregulation of ascorbate-glutathione cycle is higher in P. juliflora and it plays a great role in making P. juliflora more tolerant under high salinity conditions.
On the effect of Printing orientation on the surface Roughness of an Additive Manufactured Composite Vertical Tail
Authors: Acanfora Valerio , Garofano Antonio , Battaglia Miriam , Maisto Giovanni , Riccio Aniello
Published: August 2023

Additive manufacturing (AM) enables the production of customised and sophisticated components; Fused Filament Fabrication (FFF) is a widely used and cost-effective AM technique. Nevertheless, the use of FFF for aerospace and aeronautical applications is often impeded by the inadequate surface finish it imparts to the produced components. This work aims to demonstrate that, with careful calibration of process parameters and build orientation, FFF can produce aerospace components with low surface roughness. This could enable FFF to be used in aeronautics, allowing the benefits of lightweighting structures using metal replacement thermoplastics and variable infill to be exploited. In this study, rudder sections of a UAV tailplane were produced using FFF and lightened through variable internal infills, thin thicknesses, and a polymer for metal replacement. By setting different printing processes, a configuration was identified that exhibits suitable surface roughness for aerospace applications and a weight saving of approximately 50% compared to an equivalent metal volume.
A New Trend in The Sustainability of Ethnic Cultures: Ethno-Fest
Authors: Sormaz Ümit , KIDIRALIYEV Nurudin , SAMATOVA Gülmira , İSAKOVA Dinara , TURGANBAEVA Nadira , TURDUBEKOVA Sapargül
Published: August 2023

Recently, popular gastronomy is an important tourism activity in the promotion and marketing of societies, cultures and tourism products. Festivals, which are included in tourism, are an important tourism activity in attracting tourists to the region. This study was carried out in order to introduce ethno-fests, which is a new trend in ensuring the sustainability of ethnic culture within the scope of sustainability, and to make it widespread in countries. The data of the study were obtained by the field observation method carried out by the researchers. The researchers who participated as observers of the "1st Supara: Traditional Cuisine of Turkish Peoples Ethno-Fest" organization, the first of which was held in Bishkek/Kyrgyzstan, were observed in the festival area, and those with ethnic characteristics were given in the study. As a result of the study, the importance of introducing ethnic culture, ethnic cuisine culture, ethnic dishes, transferring them to future generations by transferring them to written sources, and reviving the lost ethnic identity characteristics has been emphasized.
Synthetic streamflow generation using Artificial Neural Network
Authors: Shaikh Safayat Ali , Bhowmick Prasenjit
Published: August 2023

In this study, Artificial Neural Network (ANN) models have been developed as an alternative to classical stochastic auto regressive model for monthly streamflow generation at multiple sites of a river basin. In the ANN model development a three-layer fully connected feed-forward network was developed using log-sigmoid and pure-line activation function in hidden layer and output layer respectively. Monthly neural network models have been designed for simultaneous generation of streamflows in two sites at a time. Training of those models has been done in supervised environment with back-propagation algorithm. The network has been selected based on its minimum mean square error. Available historical flow sequences of a river basin have been partitioned into three parts at 2:1:1 ratio. The first partitioned portion of the historical flow sequences were used to generate 50 sets of flow sequences with the help of multi-site first order Markov model. The generated flow data were used to train the ANN model. The trained ANN model were simulated with the second partitioned historical flow data. The simulated results have been compared with the third partitioned historical flow data in terms of statistical parameters- means, standard deviations, serial correlations and cross correlations. The ANN models so developed have been applied at four sites of Damodar River Basin: (i) two sites (Konar and Panchet) on River Damodar and (ii) two sites (Tilaiya and Maithon) on river Barakar, tributary of river Damodar, in India using available 56 years (1960–2015) of historical flow data. Statistical parameters: means, standard deviations, serial correlation coefficients and cross correlations (lag-zero, lag-one and lag-two) of historical and ANN generated series are compared. Those results indicate that all those statistical parameters as obtained from historical flow series are well preserved in the flow series generated by the ANN models.
Associations of blood metals and metal mixtures with myocardial enzyme profile: an occupational population-based study in China
Authors: Ge Xiaoting , He Junxiu , Zheng Yuan , Cheng Hong , Bao Yu , Lin Sencai , Hu Sihan , Cai Haiqing , Feng Xiuming , Fan Qinghua , Wang Lin , Wang Fei , Liu Chaoqun , Chen Xing , Yang Xiaobo
Published: August 2023

To investigate cross-sectional association between blood metal mixture and myocardial enzyme profile based on an occupational population. We determined creatine kinase (CK) and creatine kinase-MB (CK-MB), lactate dehydrogenase (LD), α‐hydroxybutyrate dehydrogenase (α‐HBD) and aspartate transaminase (AST) among participants from the manganese-exposed workers healthy cohort (n = 544). Levels of 22 metals in blood cells were determined using inductively coupled plasma mass spectrometry. Least absolute shrinkage and selection operator (LASSO) penalized regression model was utilized for metals screening. Exposure-response relationship between specific metal and myocardial enzyme profile was identified by general liner regression and restricted cubic spline analyses. The overall effect and interactions were evaluated with Bayesian kernel machine regression (BKMR). Manganese was linearly and positively associated with CK (Poverall = 0.019, Pnon-linearity = 0.307), dominating positive overall-effect of mixture exposure (manganese, arsenic and rubidium) on CK level; calcium and zinc were linearly negative associated with LD level (Poverall < 0.05, Pnon-linearity > 0.05) and asserted dominance in the negative overall-effect of metal mixtures (Rubidium, molybdenum, zinc, nickel, cobalt, calcium and magnesium) on LD level. It was interesting to note a “U” shape dose-response relationship of molybdenum with LD level (Poverall < 0.001, Pnon-linearity = 0.488). There was an interaction between age and calcium on LD level (Pinteration = 0.041). Besides, there was an interaction between smoking and molybdenum on LD level (Pinteration = 0.035). Our study provides evidence that metal mixture exposure affects myocardial enzyme profile. Additional investigations are required to confirm these associations and reveal the fundamental mechanisms involved.
Stem Cells Derived Exosomes Vincristine Sulfate Loaded as Potential Biological Nano Carriers for Treatment of Breast Cancer Stem Cells
Authors: Farouk Ahmed H. , Aref Ahmed , Fathy Belal A. , Abdallah Ahmed N.
Published: August 2023

Due to vincristine sulfate's (VCR sulfate) toxicity and non-specific targeting, which might adversely damage healthy cells, its clinical application is restricted. In this study, we loaded VCR sulfate on exosomes generated from mesenchymal stem cells (MSCs) to enhance its targeted distribution. Exosomes are able to deliver molecules to specific cells and tissues and have therapeutic potential. In this study we isolated exosomes from MSCs, and using probe-sonication approach loaded them with VCR sulfate. Using SRB assay, cytotoxicity of VCR sulfate-Exo was assessed in T47D breast cancer cells, and the results were contrasted with those of free VCR sulfate. Then We labelled markers (CD44+/CD24-) in the cell line to assess the targeting effectiveness of VCR sulfate-Exo using flow cytometry. Our results showed that the cytotoxicity of VCR sulfate-Exo was nearly the same as VCR sulfate. Analysis using flow cytometry revealed that VRC sulfate-Exo was more effectively targeted to MSCs than free VCR sulfate. Our study shows that loading VCR sulfate to MSCs derived exosomes can improve their targeted delivery and lessen their side effects. Additional research is required to determine the in vivo effectiveness and safety of VCR sulfate-Exo and to improve the loading and delivery strategies.
The impact of religiosity and spirituality in the health context of resident physicians
Authors: Dias Alzira Maria Cussi Brasileiro , Silva Adriana Paula , Silva Élida Mara  Carneiro , Tomé Janaíne Machado , Lara Beatriz Hallal Jorge , Abreu Ana Cecília Borborema , Nico Elisa Bernardes , Ataíde Meire Soares , Borges Maria de Fátima , Ribeiro Flávia Alves
Published: August 2023

BACKGROUND: Literature has pointed out benefits of inserting religiosity and spirituality (R/S) in patient care, indicating the need of training health professionals in this subject. However, it is necessary to take care of those who take care. So it is essential to study the role of R/S in one of the professional segments that are in the front lines of patient care.
OBJECTIVE: Analyze the profile of R/S of resident doctors and its role in their life quality and well-being.
METHODS: This is a cross-sectional quantitative study and describes the reality of 51 resident physicians. Data were obtained through self-administered instruments: Social Demographic Questionnaire; Perception of R/S; BMMRS (Brief Multidimensional Measure of R/S); SWBS (Subjective Well-Being Scale); WHOQOL-Bref (Whoqol Health Organization Quality of Life); MBI (Maslach Burnout Inventory). Data were analyzed by Statistical Packge for the Social Science/23.The study was approved by the Research Ethics Committee, opinion 2,770,936.
RESULTS: From the 51 resident doctors, 74.5% were female, 70.6% between 26 and 30 years old, 74.5% white, 64.7% Catholic. BMMRS: most believe that R/S provides positive support for coping with stressful situations. SWB-S found a high rate of positive emotions, lower rates of negative emotions and satisfaction with life. WHOQOL: assessed good life quality and fair health satisfaction. MBI identified moderate emotional exhaustion, low depersonalization and a high level for low professional achievement.
CONCLUSION: We conclude that R/S interferes positively in the resident doctors life quality and in the prevention of burnout syndrome, helping them face the challenges during the period of training represented by the medical residency.
Statin therapy in patients undergoing short-course neoadjuvant radiotherapy for rectal cancer: A retrospective cohort study
Authors: McKechnie Tyler , Schep Daniel G. , Cardenas Luisa M. , Wong Raimond , Levine Oren , Doumouras Aristithes G. , Eskicioglu Cagla
Published: August 2023

Purpose
There is a potential benefit with concurrent statin use and neoadjuvant therapy for rectal cancer. The impact of statins on pathologic response following short-course neoadjuvant radiation has yet to be studied. This study aimed to elucidate the impact statin use on tumor response to short-course neoadjuvant radiation.
Methods
This retrospective cohort study included patients receiving short-course neoadjuvant radiation and subsequently undergoing oncologic resection for stage II/III rectal adenocarcinoma from 2014–2020. Exclusion criteria included recurrent disease, total neoadjuvant therapy (TNT), and oncologic resection less than six weeks after neoadjuvant therapy. The primary outcome was pathologic complete response (pCR). Secondary outcomes included graded pathologic response and incidence of radiation-associated toxicity. Univariable logistic regressions and stepwise multivariable logistic regressions were performed.
Results
Seventy-nine patients (mean age: 68.6 ± 11.2 years, 39.2% female) met inclusion criteria. Prior to neoadjuvant therapy, median T-stage was 3 (range: 1–4), median N-stage was 1 (range: 0–2), and mean tumor distance from the anal verge was 6.3cm (± 2.9). Thirty-five patients (44.3%) were using statins. Overall, 7.6% experienced pCR and 29.1% had no treatment response on pathology. Radiation-associated toxicity was 43.0%. Statin use was not associated with pCR (OR 2.71, 95%CI 0.47–15.7, p = 0.27), however on stepwise multivariable logistic regression, statin use was associated with decreased prevalence of no response (OR 0.08, 95%CI 0.01–0.43, p = 0.003).
Conclusions
Statins may offer a synergistic effect when given concurrently with short-course neoadjuvant radiation for rectal cancer. Further prospective study evaluating the use of statins in conjunction with neoadjuvant therapy is warranted.
Methyl Jasmonate as a resistance inducer to Drosophila Suzukii Matsumura (Diptera: Drosophilidae) in greenhouse strawberry
Authors: Meyer Augusto Leal , Sant’Ana Josué , Jahnke Simone Mundstock , Shimbori Eduardo Mitio
Published: August 2023

Drosophila suzukii Matsumura (Diptera: Drosophilidae) is an important and novel pest in strawberry crops, thus the study of tools that activate the natural defense mechanisms using plant endogenous hormones is relevant. In the present study, strawberry plants (Fragaria x ananassa Duch.) were treated with three concentrations of methyl jasmonate (MeJa) to assess effects on population fluctuation, oviposition, and emergence of D. suzukii over time, as well as the physical-chemical properties of strawberries. The highest densities of D. suzukii occurred in the first two collections before the application of treatments in the area. The average number of insects captured in the third collection (first after applying MeJa in the area) was significantly lower than in the previous two. The total average (five collections) of eggs and the emergence of flies in fruits from strawberry sprinkled with 0.5 mM and 1 mM of MeJa was lower than those recorded with only water, which did not differ from ethanol at 1% (Et), for both factors. A more saturated shade of red was observed for fruits with 0.5mM in relation to water and Et and there were no differences of total titratable acidity and total soluble solids in fruits from strawberries sprayed with all treatments. The application of MeJa at 0.5 and 1 mM caused a smaller number of eggs deposited in the fruits and adults that emerged from them without influencing the physical-chemical properties.
Microplastics accelerates the premature aging of blood vessels though ROS-mediated CDK5 signaling pathway
Authors: Wang Kaihao , Du Yipeng , Li Peixin , Guan Chang , Zhou Min , Wu Lanlan , Liu Zengfu , Huang Zheng
Published: August 2023

Background
Microplastic has become a kind of pollutant widely existing in soil, atmosphere, fresh water and marine environment. At present, microplastics have been found in many tissues and organs of organisms. Research shows that as a new environmental pollutant, microplastics has shown a health hazard to human and animal. Aging and aging-related diseases are major social and medical problems facing the world. However, up to now, the effect of microplastic exposure on premature aging of blood vessels has not been evaluated. Therefore, we investigated the health damage of microplastics to blood vessels in vivo and in vitro experiments.
Methods
ELISA, indirect immunofluorescence, SiRNA, laser confocal microscopy, and Flow cytometry were performed to evaluate the effect of microplastics on premature aging of blood vessels.
Results
In vitro experiments, we found that microplastics can internalize into vascular cells, and the internalized microplastics cause damage to organelles. Further biochemical experiments showed that microplastics stimulation caused the premature aging of blood vessels by detecting a series of aging markers. Further mechanism research indicates that microplastics could increase ROS level of mitochondria mediated by calcium overload, and then ROS leads to the LaminA degradation by CDK5 mediation, further resulting in genomic instability, thus finally causing the aging of vascular cells/tissues. In vivo model, we found that microplastics induced aging damage on vascular tissue, the expression of aging maker molecules were significantly increased. Furthermore, the level of inflammation and oxidative stress was also significantly increased.
Conclusion
In summary, in this work, we evaluated the effect of microplastic exposure on premature aging of blood vessels, and we also revealed the molecular mechanism by which microplastics cause premature aging of the cardiovascular system.
Calcium oxide as synergistic catalyst for oxygen reduction reaction on strontium-doped lanthanum ferrite for SOFC
Authors: Xu Wenming , Li Chengyu , Hong Tao , Pan Xiang , Lu Yingwei
Published: August 2023

CaO is demonstrated as a synergistic electro-catalyst for oxygen reduction reaction on strontium-doped lanthanum ferrite (La0.8Sr0.2FeO3-δ, LSF) cathodes for intermediate-temperature solid oxide fuel cells based on ytrria-stabilized zirconia (YSZ) electrolytes. With 3.01wt% CaO, the interfacial polarization resistance at 750°C is reduced from 0.83 to 0.42 Ω cm2 for LSF-SDC (samaria doped ceria) composite electrodes on the YSZ electrolytes. With 3.2wt% CaO, the peak power density at 800°C is increased from 0.45 to 0.58 Wcm-2 for anode supported single cells consisting of Ni-YSZ anodes, YSZ electrolytes and LSF-SDC cathodes. The CaO particles can greatly enhance the kinetics of oxygen reduction reaction on LSF such as improving the oxygen surface exchange coefficient at 750°C from 1.9×10− 5 to 54×10− 5 cm s-1 as demonstrated by the electrochemical conductivity relaxation measurement. Specifically, CaO particles infiltrated to the LSF electrodes reduce the interfacial polarization resistance associated with the low-frequency response, which is often attributed to the surface reaction steps of the cathode reaction.
P-power log-convex function and its applications
Authors: Jiang Shenming , Nie Mei
Published: August 2023

In this paper, the concept of p-power log-convex function is introduced. Some properties and discriminant criterion of p-power log-convex function are shown. Some examples are given. Several integral inequalities for p-power log-convex functions are proved. As an application, an extended weighted average inequality is given. The p-power log-convexity of Gamma function is researched, and two exponential function expansion residual inequalities are given.