bluuebunny/crossref_metadata_2025 huggingface dataset:
Formação de anfitriões para a oferta de hospedagem compartilhada no Turismo de Base Comunitária
Authors: Abreu Leonilo Alves de , Gruber Crislaine
Published: October 2024

Este relato de experiência apresenta o projeto de extensão Minicurso Hospedagem Compartilhada no Turismo de Base Comunitária (TBC), do Instituto Federal de Santa Catarina, cujo objetivo foi a criação e execução de um minicurso autoinstrucional on-line que oferecesse formação profissional aos coletivos de TBC para a oferta da hospedagem em suas residências. O curso, com um mês de duração e carga horária de 20 horas, foi criado por um estudante extensionista da Especialização em Tecnologias para Educação Profissional, sob orientação da professora, e contou com cinco módulos que abordaram assuntos introdutórios sobre turismo, hospedagem, sustentabilidade e práticas operacionais a serem usadas no dia a dia das atividades no TBC. Para a formação dos participantes, foi organizada uma plataforma de aprendizagem com diversos recursos educacionais tecnológicos como vídeos, infográficos, podcast e outros. A elaboração desses materiais ocorreu durante a Especialização, principalmente em suas aulas práticas, nas quais os alunos foram desafiados a explorar as ferramentas de autoria educacionais. Tivemos 47 inscrições e 16 participantes foram certificados ao final. Este relato apresenta o contexto do projeto de extensão, o processo de criação e de oferta do Minicurso, as atividades desenvolvidas e a avaliação dos participantes. O discente extensionista experimentou na prática a criação dos recursos didáticos para o meio digital e a docência on-line, em contato com a comunidade externa. A ação proporcionou difusão de conhecimentos sobre o TBC e incentivo ao aperfeiçoamento na área.
O papel da arte na pandemia: possibilidades de aprendizagem e recreação a partir do desenvolvimento de atividades remotas de pintura
Authors: Boechat Lorena Temponi , Bess Márcio Luiz , Freitas Nathália Luiz de
Published: October 2024

Investigou-se a percepção de alunos de uma oficina de pintura, fruto de um projeto de extensão, sobre a continuidade do curso no período de isolamento social, com ênfase nas especificidades relativas ao novo modelo de ensino-aprendizagem, na atuação dos professores, no alcance das plataformas interacionais utilizadas e na importância das atividades desenvolvidas para a manutenção da qualidade de vida dos cursistas. A coleta e a análise de dados baseiam-se na aplicação de um questionário. A maioria dos participantes prefere a modalidade presencial, que considera mais produtiva, embora admita a importância da manutenção do curso de forma remota, já que isso contribui para o bem-estar, saúde mental e aprendizagem. É notório que a tecnologia reduz distâncias e facilita a interação nesse momento que estamos vivendo, mas, não substitui o contato físico.
Municipal Leadership for Afterschool: Citywide Approaches Spreading Across the Country: Executive Summary
Authors: Spooner Bela Shah
Published: October 2024

An executive summary of the report
The correlation between bacteria and colorectal cancer
Authors: Zhang Qi , Zhao Qin
Published: October 2024

Colorectal cancer (CRC) is the third most commonly diagnosed cancer with a high mortality rate worldwide. The global burden of CRC imposes the need to understand the mechanism of CRC progression. Accumulating evidence reveals gut bacteria may contribute to the risk of CRC. The purpose of this project was to determine whether the bacterial composition is altered in stool samples of CRC patients. We hypothesized that patients with CRC would have a set of differentially abundant bacteria species in their stool samples compared to the control samples. Using 11 CRC datasets across 9 countries, consisting of 1395 samples from the curatedMetagenomicData database, we examined the bacterial composition and compared the prevalence and relative abundance of bacteria species across 701 CRC patients and 694 control samples. We found that CRC-associated bacteria species and their prevalence varied across different demographic regions. Combining 11 datasets, we performed differential abundance analysis to analyze the prevalence and compare the relative abundance of bacteria species between CRC samples and control samples, and we found a set of CRC-associated bacteria species that were significantly more abundant than those of control samples. Many of these species have previously been found to influence CRC development. Moreover, we identified a set of control-associated species that were important in maintaining a beneficial microbiome. This project provided insights that support further investigation into the role of CRC-associated bacteria in CRC tumorigenesis.
simulador conservação de energia mecânica – SimuFísica
Authors: Souza Marco Polo Moreno de , Oliveira Cristiane Mara , Araújo Rhakny Patryky Peixoto
Published: October 2024

Atualmente, os benefícios do uso de simulações computacionais no ambiente escolar são amplamente reconhecidos pelos educadores. O incentivo ao uso dessas simulações nas salas de aula é respaldado pela Base Nacional Comum Curricular, um documento normativo que define as aprendizagens essenciais para a educação básica. Este artigo concentra-se na exploração do simulador Conservação de Energia Mecânica, um simulador gratuito desenvolvido com o propósito de ilustrar as transformações entre as energias cinética, potencial gravitacional e potencial elástica. Esse aplicativo faz parte do SimuFísica, um software multilíngue e multiplataforma que oferece simuladores computacionais para o ensino de física que funcionam tanto on-line quanto off-line. Ao longo do artigo, são apresentados de maneira objetiva algumas características da plataforma SimuFísica e os detalhes do funcionamento do simulador Conservação de Energia Mecânica. Dois exemplos ilustrativos são apresentados, demonstrando o aplicativo em ação na resolução de problemas de mecânica.
Valorização do soro de leite. Tecnologias e aplicações na indústria alimentar. Vol. 1.
Authors:   Universidade Estadual de Maringá, Javier Sucari Pither Jhoel , Valeriano Mamani Máxima Elizabeth ,   Universidade Nacional de Juliaca (UNAJ), Jara Huarancca Rolando Rody ,   Universidade Nacional de Juliaca, Montufar Avendaño Julia Dolores , Huanático Suárez Elizabeth ,   Universidade Nacional de Juliaca, Arisaca-Parillo Adaliht Jhony ,   Universidade Nacional de Juliaca, Cosi-Cutipa Ruben Virgílio ,   Universidad Nacional de Juliaca, Lima Hurtado Mariela ,   Universidade Nacional de San Antonio Abad de Cusco, Turpo Mamani Yesenia Milagros , Rodrigues da Luz Renan Gustavo , Cruz Hugo Laura
Published: October 2024

O soro de leite, um subproduto da produção de queijo e outros produtos lácteos, evoluiu de ser considerado um resíduo sem valor para se tornar um recurso valioso com aplicações inovadoras. Este livro examina detalhadamente o soro de leite, abordando tudo, desde sua geração até seu uso em diversas indústrias, e os desafios relacionados à sustentabilidade ambiental. A geração e disponibilidade de leite e soro de leite são essenciais para compreender o seu impacto. A produção de leite aumentou globalmente, o que aumentou a quantidade de soro de leite gerada. Para cada quilo de queijo produzido, são obtidos aproximadamente nove quilos de soro de leite. Esta abundância coloca desafios na sua gestão, uma vez que o soro contém proteínas, lactose, minerais e vitaminas, componentes que podem ser valiosos se forem processados adequadamente. O livro detalha os métodos de processamento do soro de leite, essenciais para a sua valorização. Técnicas avançadas como ultrafiltração, nanofiltração e spray drying permitem que seus componentes sejam separados e concentrados, gerando produtos como concentrados e isolados de proteína de soro de leite (WPC e WPI). Esses produtos possuem alto valor na indústria alimentícia devido às suas propriedades nutricionais e funcionais. Na indústria alimentícia, os derivados do soro de leite são utilizados em suplementos nutricionais, bebidas esportivas e produtos de panificação. As proteínas do soro são valorizadas pelo seu valor biológico e digestibilidade, enquanto a lactose é utilizada como adoçante. Estas aplicações permitem-nos desenvolver alimentos mais saudáveis e funcionais, respondendo às exigências do mercado. Um aspecto crucial do livro é o impacto ambiental e a sustentabilidade. O manejo inadequado do soro pode causar contaminação, tornando essencial a adoção de práticas sustentáveis. A economia circular, que procura reutilizar e reciclar componentes do soro de leite, é uma estratégia fundamental para minimizar o desperdício e melhorar a eficiência. Este livro é direcionado a estudantes, pesquisadores e profissionais, oferecendo uma visão abrangente do soro de leite e seu potencial para promover a sustentabilidade na indústria. Através de inovações tecnológicas e do foco na sustentabilidade, o soro de leite pode tornar-se um recurso valioso e versátil em vários setores.
THERAPEUTIC, RESTORATIVE AND BIOTECHNOLOGICAL RESOURCES OF SCIENTIFIC MUSIC THERAPY IN SOLVING INFERTILITY PROBLEMS
Authors: Shushardzhan Sergey
Published: October 2024

Scientific music therapy is an advanced therapeutic and preventive direction, widely in demand in various areas of health care, psychological assistance, and social rehabilitation, but still underestimated in reproductive medicine. Complex scientific research conducted over thirty years has helped to better understand the nature of the main mechanisms of music's influence on the neuroendocrine system,vital organs, and cellular structures. On this basis, unique and effective methods of scientific music therapy and promising biotechnologies have been created, the possibilities of which in solving infertility problems are discussed in this article.
ETHICS AND DEONTOLOGY AS A BASIC PRINCIPLE OF THE WORK OF A MULTIDISCIPLINARY REHABILITATION CENTER USING METHODS OF SCIENTIFIC MUSIC THERAPY
Authors: Allik Tatyana
Published: October 2024

This article presents literary data on the history of the formation of norms and rules of medical ethics. It substantiates the position on the need to comply with them in medical and preventive institutions not only by doctors or nurses, but also by employees of other specialties, such as psychologists, music therapists, etc. The advantages of combining medicine and art, innovative technologies in scientific music therapy, and the norms of medical ethics in practical activities are shown using the example of the multidisciplinary rehabilitation center «Doctor Music from Estonia». Compliance with these principles has ensured a reputation as an advanced organization, as well as respect and trust from the population. Such experience may be useful for other medical and preventive organizations.
MESO-FORTE THERAPY IN REHABILITATION OF CHILDREN WITH MYOPIA — PILOT STUDY
Authors: Terehova Angelina , Kondratova Svetlana
Published: October 2024

This article presents the results of a pilot clinical and experimental study of the prospects for neurorehabilitation of children with myopia using Meso-Forte Therapy (MFT), an innovative hardware method of restorative treatment using digital music therapy programs. For the first time, data from complex psycho physiological and ophthalmological studies is published, revealing the mechanisms of corrective regulation of the psycho emotional status, the autonomic nervous system, and the tone of the accommodating muscles of the eye using the main algorithms of musical and acoustic effects.
Към историята на Будапещенската конвенция от 1877 г.
Authors: Макарова Ирина
Published: October 2024

Статията разглежда дипломатическия контекст на Руско-турската война от 1877-1878 г. и по-специално преговорите между руската и австро-унгарската дипломация в навечерието на конференцията на посланиците в Истанбул и след това. Нови документи савъведени и анализирани, главно от кореспонденцията между руския посланик във Виена Е. П. Новиков и руския външен министър А. М. Горчаков, съхранявана в Архива за външна политика на Руската империя. На този фон е разгледана последователната позиция на Австро-Унгарската империя, представена в преговорите от граф. Д. Андраши, и ясно заявените амбиции и цели на руския император Александър II.
Новооткритите документи категорично развенчават мита за Руско-турската война по отношение на пасивността и нерешителността на руския император по време на Източната криза, както и на самоотвержената руска защита на интересите на балканските славяни, представлявани главно от сърби и българи. Материалите опровергават и твърдението за сериозни дипломатически отстъпки пред Австро-Унгария. Документът ясно илюстрира, че във висшето ръководство на Руската империя е имало ясно разбиране и ясно дефинирано преследване на целите и интересите на собствената страна, както и твърда воля и последователност в тяхното осъществяване, независимо от надеждите и претенциите на турските християни.
Работна заетост сред циганското население на България в годините на социализма
Authors: Стоянова Пламена
Published: October 2024

В статията е направен кратък преглед на начина на живот на българските цигани в България преди 1944 г., но основният фокус на това изследване е върху заетостта на циганите в социалистическа България. Подробно е разгледан преходният период след Втората световна война, когато в живота на българските цигани настъпват радикални промени. Заетостта на циганското етническо малцинство в селскостопанската работа и в процеса на индустриализация, както и последващото създаване на циганската интелигенция също са важна част от статията. Новите възможности за работа, които се откриват пред българските цигани в периода на социализма, и реакциите на малцинството спрямо тях са представени и анализирани обстойно.
Начални страници, съдържание и Автори
Authors: ГСУ.ИФ
Published: October 2024

Т. 103 съдържа на първо място статията, основана на академичното слово на проф. Дмитрий Поливянни /Ивановски университет - Русия/ при удостояването му за Doctor honoris causa на 18 май 2018 г. в Аулата на Софийския университет. Статията разглежда общностите на духа в Българското средновековие, създавали специфични мрежови структури, с особен пиетет към връзката между учител и ученик. Статията на Ел. Мусакова се отнася до ръкописа наречен Банишко евангелие, като се  проблематизират отново въпросите за мястото на неговото създаване и за автора му.  Т. Попов представя статия за влиянието на българската държавна традиция върху институциите на Дунавските княжества - Влахия и Молдова за преиода XIV - XVII в. Влиянието е проследено чрез възприетите титулатури в княжествата и институции, сходни или идентични с тези в българската държава. Материалът от М. Белчева отразява процеса на реставрация на една от книгите, принадлежала на Софроний Врачански, а също така размисли на авторката относно движението на тази книга от Годард Фридрих Стендер /1714 - 1796/ Истина религии..., върху бележките, поставяни по нейните страници и др. Последната студия в броя от Дж. Маджаров разглежда в подробности тежката съдба на известната унгарска българистка Шара Кариг/1914-1999/ и нейните приноси в популяризирането на българската култура в Унгария.
Размисли върху реставрация на книга от личната библиотека на Софроний Врачански
Authors: Белчева Малина
Published: October 2024

Настоящото изследване на Истина религии вообще: в двух частях, из которых в первой доказывается истина Религии вообще противу невтърия вольнодумцов и натуралистов; а во второй утверждается истина Християнской религии, слтъдуя Священному Писанию, противу невтърия натуралистов разглежда Св. Софроний Врачански - изтъкнат раннобългарски възрожденски книжовник и духовник (1739 - 1813) - маргинални коментари и подписи в книгата и в негови ръкописи, разкрива детайли от опазването на книгата, описва историята на книгата и обстоятелствата около нейното публфициране и постъпване в специалните фондове на Библиотеката на Софийския университет.Статията представя консервацията на книгата на Г. Ф. Стендер като сложен процес, осъществен чрез сътрудничеството на специалисти от различни области на изкуството и науката. Консервацията на книгата е осъществена благодарение на подкрепата на директора на Университетската библиотека доц. д-р Анна Ангелова и със съдействието на специалисти от Университетската библиотека на Софийския университет, Факултета по класически и моделни филологии, катедра „Реставрация“ на Националната художествена академия и библиотеката на манастира „Свети Георги Зограф“ в Атон, Гърция.
Руското военно разузнаване на Балканите в двете десетилетия след Кримската война (1856 - 1876)
Authors: Симов Михаил
Published: October 2024

Изследването разкрива дейността на руското военно разузнаване на Балканите през двете десетилетия след Кримската война. Предвид обстоятелствата след Парижкия договор Русия не е в позиция за активни интервенции в Югоизточна Европа, но достатъчно ясната перспектива за бъдеща война срещу Османската империя, за възстановяване на влиянието и престижа в стратегически важния регион, налага Санкт Петербург да планира хипотетични кампания в Югоизточна Европа. Основна част от подготовката за подобно развитие на събитията е военното разузнаване, което отразява особеностите на руското военно мислене, стратегическите планове и общата политика по отношение на Балканите в сложния период между Кримската война и Източната криза от 1875-1878 г.
Въз основа на документален материал и публикувани източници изследването прави необходимия преглед на руските военни разузнавателни служби през разглеждания период и се спира на трите основни форми на дейност по събиране на информация, провеждана системно на Балканите: работата на руския военен агент в Константинопол; разузнавателните мисии на руските офицери на Балканите и ролята на руската консулска мрежа в събирането на информация от военен интерес. Непрекъснато се обръща внимание на въпросите как е била организирана разузнавателната система, какъв вид информация се е събирала основно и как тя е съотнасяла към политиката и военната стратегия на Русия на Изток. Документалните източници разкриват, че през този период основният акцент е бил върху топографското разузнаване, тъй като потенциалните бойни полета на Балканите не са били добре познати на руския военен щаб и до голяма степен не са били картографирани. Изследването стига и до извода, че тайното разузнаване и шпионажът не са сред основните средства за събиране на информация в арсенала на руските служби през разглеждания период.
Партията на радикалите по време на управлението на Демократическия сговор (1923-1931)
Authors: Стефанов Христо
Published: October 2024

Българската радикалдемократическа партия се появи като политическаорганизация на част от дребнобуржоазните слоеве. Тя не успя да стане голяма обществена сила с първостепенно значение. Нейното политическо влияние бе ограничавано от другите партии. Върху партията на радшшлите беупражняван постоянен политически и идеен натиск за коренна промяна вповедението и. Но тя се съпротивяваше на натиска и нейното участие в обществения живот на страната се чувствуваше осезателно при политическите ком-бинации на партийните групировки. Партията на радикалите в периода на управлението на Демократичесrшясговор запази самостоятелното си съществование. Тя се стремеше да се утвърди като политическа сила,която все по-ярко да се противопоставя навластта на Сговора. В политическата си дейност Радикалдемократическатапартия се ориентира към своевременно разобличаване на фашистското правителство.
Българо-югославски културни връзки
Authors: Лалков Милчо
Published: October 2024

Разnитието на българо-сръбските и българо-югославските културни отношения през ново и най-ново време показва за разлика от политическите отношения сравнително постоянната тенденция на сътрудничество, взаимност и творчески влияния. Тази констатация намира своята логика в етническото родство, приблизително еднаквите исторически обстоятелства и пътища, по които се е формирала обществено-политическата, научната и художествената мисъл на българския и югославските народи, сходството в езиците, бита, етнографските характеристики и др. Дори и македонският въпрос, на чието конфликтно поле винаги са се срещали остриетата не само на двете политически,но и на културните пропаганди, невинаги е бил в състояние да хвърли плътна сянка върху духовните контакти между тези съседни славянски народи.
Политически и социални аспекти на първоначалното разпространение на християнството в Чехия
Authors: Сотиров Георги
Published: October 2024

Налагането на християнството сред западните славяни през IX-X в. било дейно средство за военна или куmурно-политическа експанзия на стра­ ните, откъдето то се разпространявало. В по-ранния период до V-VI в. в западните провинции на Франкската държава тази роля на новата вяра била съвсем слабо изразена. По отношение на Чехия първоначалното проникване на християнството поради редица причини, някои от които ще се опитаме да обясним, се отразило по-контрастно върху развитието на вътрешнополити­ ческата и на социалната структура на чешкото общество в процеса на него­ вата еволюция към феодалнзма.В настоящата работа ще бъде разгледано предимно влиянието на идей­ ните промени в Чехия през IX-X в. върху някои вътрешни събития, а в по­ ранния период - върху процеса на утвърждаване на държавния строй. Вън­ шнополитическите аспекти ще ни: интересуват главно когато са в по-пряка връзка с вътрешните.
Политика и дейност на правителството на Народнолибералната партия в областта на културата
Authors: Радева Мария
Published: October 2024

Политиката на българските буржоазни правителства в областта на образованието и културата през първите десетилетия след Освобождението заема важно място в гражданската история на България в ново време. Специфичните условия и особености на културния живот в страната, наскоро отхвърлила националното робство, относително ограничената основа на възрожденските традиции и постижения, както и икономическите и идеологи­ ческите цели на възхождащата буржоазна класа поставят фундаментални задачи в националното културно строителство.
Phytochemical screening and toxicity assessment of compounds isolated from the leaves of Mangifera indica L. for the control of Spodoptera litura (Lepidoptera; Noctuidae)
Authors: Phankaen Poonnanan , Bullangpoti Vasakorn , Pluempanupat Wanchai , Saiyaitong Chatwadee , Temyarasilp Parinthorn , Kumrungsee Nutchaya
Published: October 2024

This study aimed to analyze the phytochemical composition and antioxidative capabilities of mango leaves (Mangifera indica L., Nam Dok Mai), indigenous to Sa Kaeo Province, Thailand. Various solvents with differing polarities, including n-hexane, DCM, ethyl acetate, and MeOH, were utilized for leaf extraction. The findings revealed the existence of eight groups of phytochemical compounds: alkaloids, flavonoids, coumarins, saponins, tannins, terpenoids, steroids, and cardiac glycosides. The MeOH crude extract exhibited the highest concentration of total phenolic compounds at 409.88 ±0.02 mg GAE/g. Furthermore, the MeOH crude extract demonstrated the strongest antioxidant activity, with an IC50 value of 0.52 ±0.02 μg/ml, as determined by the DPPH method. High-performance liquid chromatography (HPLC) was employed to identify gallic acid and mangiferin in the MeOH crude extract. Laboratory tests were conducted using the topical application method to evaluate the toxicity of the M. indica leaf crude extract on 2nd instar Spodoptera litura larvae. The MeOH crude extract exhibited high efficacy, with an LD50 value of 10.58 µg per larvae within 24 hours. Gallic acid and mangiferin were identified as the primary active ingredients, with LCD50 values of 1.19 µg per larvae and 1.90 µg per larvae, respectively, within 24 hours. Additionally, the impact on detoxification enzymes (24 hours post-treatment) was assessed in surviving 2nd instar S. litura larvae using the topical application method. The MeOH extract treatment resulted in 1.31-fold inhibition of carboxylesterase (CE), 1.31-fold inhibition of glutathione-S-transferase (GST), and 1.32-fold inhibition of acetylcholinesterase (AChE).
The Science of Constitutional Law in the System of Other Sciences
Authors: Lazarev Valeriy
Published: October 2024

The article puts forward a prescriptive hypothesis, according to which the complex of legal sciences is based on synergetic rhizomorphic spheres that inherently have the creative potential of self-organization and, accordingly, the organization of scientists’ work. The latter, in civilizational conditions, are guided by the principle of constitutionalism. As a result of its verification, the author’s earlier conclusion is confirmed that constitutionalism, as an idea and then as a practice, developed from the need for procedural mediation of the organization and activities of the existing government. This conclusion is associated with an integrative understanding of constitutionalism, conditioned by a broad understanding of the constitution in a threefold aspect: as a real relationship of political forces, an idea of the necessary organization of power, and a written text. From these positions, the thesis is substantiated according to which a full-fledged understanding of constitutional law can only be obtained by considering it in the system of sciences, the subjects of which in one way or another involve legal regulation.Constitutionality as the main category of constitutional law receives meaningful content not only in the system of legal sciences, but also beyond its limits, where social relations included in the subject of a variety of sciences form synergetic rhizomorphic spheres that inherently have the creative potential of self-organization and, accordingly, organization research work towards ensuring the principle of constitutionalism. Therefore, the scientific system of constitutional law cannot be limited to narrow issues of the industry. Focusing attention on specific constitutional legal institutions, constitutional law also takes into account everything that comes from other sciences in characterizing these institutions. And not only from legal ones, but also from others, especially from public ones. A reasonable expansion of the subject of the science of constitutional law does not “erosize” it, but significantly enriches and strengthens it.
The Metaverse: Problem of Adapting Tax and Legal Structures
Authors: Khavanova Inna
Published: October 2024

The article is devoted to the analysis of theoretical and legal aspects of income taxation and transactions in the metaverse. The scientific interest of the author is connected with the problems of adapting tax and legal structures to economic relations, which are generated by unique technologies of the virtual world. Purpose: to reveal the legal nature of the metaverse economy for tax purposes; to identify the most common problems associated with the application of tax legislation. Methods: the study is based on the methods of comparison, analysis, synthesis, generalization, and formal-logical method. Results: analysis of the bases and principles of taxation of income and transactions in the metaverse (income tax, value added tax), analysis of the tax consequences of specific situations, formulation of basic principles of taxation. Conclusions: the conducted scientific analysis confirms that national regulators and tax authorities are only at the stage of understanding the problems that arise in the metaverse, including issues related to determining the moment of income, evaluating transactions for the exchange of virtual goods for virtual or fiat currencies. The author comes to the conclusion that the technical impossibility of flawlessly accurate calculation of the tax base and determination of the source of income in a space of which anonymity is an integral component should not serve as a basis for non-taxation. The solution to the problem of creating tax and legal structures focused on the metaverse consists in taking into account the specifics of legal situations (a hybrid approach), using presumptive taxation in segments of high risk of losses for the national tax base, introducing a special regime for cases when income is received outside of entrepreneurial activity, is insignificant, and is of a one-time nature. The article points out the need for tax rules to comply with the basic principles of legislation on taxes and the inadmissibility of excessive tax burden.
Relación de la adherencia terapéutica con el nivel de glicemia preprandial en personas con diabetes mellitus tipo 2
Authors: Ramos Merino Jorge , Ruiz Recéndiz Ma. de Jesús , Lozano Zúñiga María Magdalena , Leyva Ruiz Julio César
Published: October 2024

Introducción. La adherencia terapéutica se erige como un factor determinante en el control de la glicemia preprandial, siendo esencial para prevenir las complicaciones micro y macrovasculares asociadas a la diabetes mellitus tipo 2. Objetivo. Evaluar la relación de la adherencia terapéutica con el nivel de glicemia preprandial en personas con diabetes mellitus tipo 2. Metodología. Estudio cuantitativo, no experimental, descriptivo y transversal. Muestra no probabilística de 138 personas de varias colonias de Morelia, Michoacán, México; selección a conveniencia. Estadística descriptiva para análisis de los datos. Resultados. Del total, 60.1% eran mujeres, 60.1% casadas, 39.9% nivel primaria, 81.2% católicos. El nivel de adherencia terapéutica fue alto (51.4%). Conclusiones. Cinco de cada 10 participantes tienen un nivel alto de adherencia terapéutica; enfermería debe reforzar sus estrategias de educación continua, con seguimiento individualizado y empoderamiento a cada paciente para el logro de los objetivos terapéuticos.
Desenvolvendo Habilidades: A Integração de Alfabetização e Letramento na Educação Infantil
Authors: Magnago Walaci
Published: October 2024

A alfabetização e o letramento, embora relacionados, são processos distintos que vão além do simples ato de ler e escrever. A alfabetização refere-se à capacidade de entender como os sons da fala são transformados em letras, ou seja, o reconhecimento do sistema de escrita e a relação entre fonemas e grafemas. Já o letramento está ligado ao uso e à aplicação desse conhecimento de maneira funcional, permitindo que os indivíduos utilizem a leitura e a escrita em diferentes contextos sociais e comunicativos.
Este artigo tem como objetivo investigar o processo de alfabetização na educação infantil, analisando como ele se insere no ambiente escolar e contribui para o desenvolvimento de metodologias eficazes no ensino da leitura e da escrita. Ao abordar o papel da alfabetização, o estudo destaca sua importância para a base educacional das crianças, especialmente no que diz respeito à construção das habilidades iniciais de leitura e escrita, que servirão de alicerce para os próximos estágios da vida escolar.
Além disso, o artigo explora a concepção de letramento e seu impacto no processo de ensino-aprendizagem. O letramento é tratado como uma habilidade essencial para que as crianças possam não só dominar a técnica de leitura e escrita, mas também aplicar esse conhecimento de forma significativa no cotidiano. Para isso, são propostas abordagens lúdicas que estimulam o interesse das crianças e tornam o aprendizado mais atrativo e engajador.
Por fim, o estudo propõe que a combinação de alfabetização e letramento, quando trabalhada de forma integrada e criativa, promove uma aprendizagem mais completa e contextualizada, contribuindo para que as crianças desenvolvam habilidades linguísticas que vão além do domínio técnico, capacitando-as a usar a leitura e a escrita de maneira efetiva e consciente em sua vida cotidiana.
dentification of artemether-lumefantrine combination drugs using mid-infrared spectroscopy and chemometric tools
Authors: ADJAGBONI Armel Sèna
Published: October 2024

The high circulation of substandard and/or falsified medicines is a major public health problem worldwide, particularly in low-resource countries. This work was carried out with the aim of combating this scourge using mid-infrared spectroscopy. The study focused on combination therapies based on artemether-lumefantrine and involved the construction and validation of a model for rapid detection of falsifications of artemether-lumefantrine. Other antimalarial drugs were also used to assess the specificity of the models constructed. A total of 46 samples were analyzed, all collected in Benin, from pharmacies in Departmental Hospital Centres and private pharmacies. The spectra recorded in the range from 4000 to 650 cm-1 were preprocessed then a principal component analysis was applied to break down and visualize the data, and to highlight groupings or trends. This enabled to observe the differences and similarities between the spectra of artemether/lumefantrine, and to assess the differentiating factors from other antimalarial molecules. Also, a data-driven soft independent modelling of class analogy (DD-SIMCA) model was built to evaluate its ability to authenticate artemether-lumefantrine samples. The other antimalarial drugs were used to test model specificity. Built DD-SIMCA model allowed a clear identification of artemether-lumefantrine (sensitivity 100%) and a good discrimination of other antimalarials (specificity 98%). Keywords: Quality control, construction, validation, DD-SIMCA.
Screening phytochimique et étude de l’activité antioxydante de trois plantes médicinales de la pharmacopée traditionnelle du Niger : Vernonia amygdalina Del., Tephrosia purpurea (L.) et Momordica ba
Authors: DJATAOU Bahari KASSOUM
Published: October 2024

Considering the potential role in food industry and human health, antioxidants are gaining popularity all across the globe. Antioxidants are defined as a substance that even in small amounts, is capable of preventing or delaying the oxidation of easily oxidizable materials. In this work, different parts of three plant species of the Niger Pharmacopoeia (Vernonia amygdalina Del., Tephrosia purpurea (L..) and Momordica balsamina (L..) were studied. Tube characterization reactions were used for phytochemical screening. The Folin-Ciocalteu and aluminium trichloride methods were used to determine the total polyphenol and flavonoid content. The antioxidant activity of the various crude extracts was determined through DPPH tests. Two types of extraction were used for these tests : maceration and decoction, and raw extracts were used for the work. The results of phytochemical screening showed on the different plants parts indicate the presence of various chemical groups, including polyphenols, tannins, saponins, flavonoids, alkaloids, saponosides, and others.. The compounds were quantified by spectrophotometry. Quantification of the compounds by spectrophotometry showed that the aqueous extracts of the bark and leaves of Vernonia amygdalina were the richest in polyphenols (57.05±0.33 mg EAG/g and 47.062±0.88 mg EAG/g, respectively), while the hydroethanolic and ethanolic extracts of the leafy branches of Tephrosia purpurea were the richest in total flavonoids (13.79±0.28 mg EQ/g and 13.73±0.12 mg EQ/g respectively). In terms of antioxidant power, the results obtained showed that the extract of Vernonia amygdalina bark exhibited the highest antioxidant activity with an inhibitory concentration (CI50=0.0023mg/ml). Our findings showed that the aqueous extracts of these plants have antioxidant properties; which substantiated their utilization in the conventional management of specific ailments. Key words : Vernonia amygdalina, Momordica balsamina, Tephrosia purpurea, Antioxidants, Niger.
The Efficacy and Safety of Topical Cyclosporine A and its Generic Equivalency Depores Eye Drops in The Treatment of Dry Eye Disease
Authors: Papava Medea V. , Gaprindashvili Nana J.
Published: October 2024

Dry eye disease (DED) is a complex condition that can result in significant vision complications. Analyzing systematic reviews of DED treatment contributes to selecting the most effective and safe drug. This review examines the efficacy of cyclosporine A and the generic Depores ophthalmic emulsion cyclosporine 0.05% (cyclosporine 0.05%, Deva Pharmaceuticals, Turkey) in the treatment of DED. A search for scientific information in PubMed, PubMed Central, The Cochrane Library, Google Scholar databases, and the Internet was carried out using keywords: dry eye disease, Cyclosporine A, Ikervis, Restasis, generic cyclosporine 0.05% ophthalmic emulsion, Depores. The literature cited in scientific articles was also reviewed. The analysis of scientific articles allowed us to conclude about the efficacy of the Restasis–Depores generic (cyclosporine 0.05%, Deva Pharmaceuticals, Turkey) for the treatment of patients with DED who have not yet had access to this treatment. Depores is now available in Georgia, bringing a novel treatment option to patients with severe DED. The study revealed a small number of clinical studies evaluating the efficacy and safety of generic cyclosporine 0.05% ophthalmic emulsion. Given the scarcity of research articles on this generic, it is necessary to study the results of its use in the treatment of DED in Georgia, which will help improve the quality of life with a diagnosis of dry eye.
“Innovation in the Classroom: The Importance of Continuous Teacher Training”. A Systematic Literature Review
Authors: Navarro Olga Ramírez , Thomas Rina Paola Royero , Villa Yesica María Gil , Palacio Diana Marcela Guerra , Jiménez Mayra
Published: October 2024

Teacher training is a widely discussed topic in educational literature, addressing both initial preparation and the ongoing professional development of educators. Key criteria for distinguishing a comprehensive teacher include their pedagogical approach, the theory-practice relationship, and the necessary competencies that set them apart. This scientific article aims to systematically analyze the literature of various studies related to teacher training, its importance in classroom practices, and professional development, contributing significantly to the state of the art. The methodology employed is qualitative and documentary, involving an in-depth review of documents that highlight the importance of teacher training for the effective development of classroom practices.
A Historical - Grammatical Study of Genesis 3:15, the Seedbed of the Theme of Enmity in Genesis
Authors: Adjei Eric Gyan
Published: October 2024

This thesis argues that the Genesis 3:15 reveals a historical progression to hostility and competition between the snake and the woman, as well as between their offspring, which is exemplified by the enmities between Cain and Abel, Noah and Ham, Abraham and Lot, Jacob and Esau, Jacob's sons and Shechem, and Joseph. This thesis uses the Historical-grammatical approach to analyze Genesis, showing how the subject of hostility evolved throughout the book. It assumes that if the context of the text calls for it, there is sufficient latitude to employ other strategies. The thesis's understanding of enmity is informed by אֵיבָה (enmity), which is used in the LXX (ἔχθρα) to refer to foes in conflict among gentiles and personal enemies. The word study supports the idea that family animosity eventually turns into national animosity between Israel and other Canaanite countries. The discussion of animosity in Gen. 3:15 is divided into three parts: first, the serpent's attempt to get close to the woman ends in enduring hostility, second, the animosity that started with the woman and the serpent will be carried on by their offspring, and third, this conflict needs to be viewed in a progressive manner.
PREDICTORS OF ATTITUDES OF JUNIOR VOLLEYBALL PLAYERS AND THEIR
PARENTS TOWARDS THE ROMA
Authors: Ivanović Miroljub , Ivanović Uglješa
Published: October 2024

The aim of this research was to examine the contribution of features of the five-factor model of personality and the model of right-wing authoritarianism in junior volleyball players and their parents to the prediction of the variance of social distance towards Roma. The pertinent sample of participants consisted of (N = 120) adolescent athletes from the Kolubar district (M age = 14.90, SD = 0.68 years), as well as one parent of each volleyball player (age 37 years ± 4.78). The following measuring instruments were applied: A social distance scale, Big Five Inventory – BFI, and Right-Wing Authoritarianism – RWA scale. The findings of the hierarchical regression analysis, with a statistically significant 21% variance, showed that the authoritarianism of volleyball players is a dominant significant positive predictor (β = 0.24, p ≤ 0.01) of the criteria of parental social distance. This suggests that as the dimension of authoritarianism increases, individuals report greater social distance. Also, the personality trait extraversion of the fivefactor personality model, with 29% of the variability, proved to be a relevant negative partial predictor (β = -0.29, p ≤ 0.01), which signals that young athlete with a pronounced lower score on the variable extraversion express worse social distance, that is, they more often see it as a loss. The interaction function
of personality traits - the Big Five (extraversion, openness, onscientiousness, neuroticism and agreeableness) is not statistically significant in the prediction of the construct parental social distance and the construct child’s social distance, and therefore requires further studies. The results of internal
consistency indicate that the used measuring instruments are adequate for future research on the Serbian sample of athletes in adolescence. Finally, methodological limitations in this empirical study are given, its theoretical and practical implications are analyzed, as well as guidelines for further and relational research.
PREVALENCE OF SPINAL DEFORMITIES IN PRESCHOOL CHILDREN LIVING IN
THE SOS CHILDREN'S VILLAGE IN SARAJEVO
Authors: Vranešić Hadžimehmedović Damira , Podrug - Arapović Marijana , Hodžić Amila , Mašić Semir
Published: October 2024

The issue of spinal deformities, which occurs during phases of intense growth in children, has been recognized within the broader community. Certain categories of children are particularly vulnerable to long-term health risks in this regard, making it important to find ways to intervene early and identify such cases. This study was conducted to assess the current state of spinal posture during one of the most sensitive phases of physiological development in a special group of preschool children. In this case, the sample included 92 preschool children aged 4 to 6 years, who have been living and growing up from an early age in the SOS Children's Village in Sarajevo, without the presence of their biological parents. The assessment of poor posture was applied according to Napoleon Wolanski (1975), which is based on determining the relationships between segmental dimensions as follows: D1 – assessment of head posture (HPA), D2 – assessment of shoulder posture (SPA), D3 – assessment of chest posture (CPA), D4 – assessment of scapula posture (SBPA), D5 – assessment of spinal posture (SP), D6 – assessment of abdominal posture (APA), D7 – assessment of leg posture (LPA), D8 – assessment of foot posture (FPA). Deviations are classified according to their severity and are assessed with so-called negative points, where: 0 points indicate no deviation, 1 point indicates a mild deviation, and 2 points indicate a significant deviation. The posture results show that 15.2% of the children have scoliosis, while 13.0% have lordosis, and 7.6% of preschoolers have kyphosis. Additionally, 30.4% of the children have flat feet, which predisposes them to long-term spinal problems, and 33.7% have significant deviations in leg posture. Numerical values of the results indicate that none of the children included in the testing had an ideal shoulder posture, i.e., a score of 0, which implies no deviation from normal, while the head posture results were also extremely poor.
APPLICATION OF DIFFERENT EXERCISE PROGRAMS IN THE PREVENTION OF
FALLS IN PEOPLE OF THE THIRD AGE
Authors: Zlatičanin Ratko , Jaganjac Amila , Kraljević Bojan
Published: October 2024

Introduction: Various exercise programs have a positive effect on reducing the risk of falls in elderly people. Consequences of falls include fractures and injuries, reduced quality of life, fear of falling, loss of selfconfidence, and self-limited activity leading to reduced physical function and social interactions. Activity limitation impairs physical capacity and increases the risk of further falls. Falls are the primary cause of injury of the elderly, which can result in serious consequences such as fractures, head injuries, and even death, placing a significant burden on the public health system. Annually, between 28 and 35% of individuals aged 65 and over experience a fall worldwide, with rates reaching 32% - 42% among those aged 70 and over. Therefore, preventing falls has become a key global goal for the older adult population. Objective: To determine the effectiveness of different exercise programs in preventing falls in people of the third age.
Methods: The search included an overview of the relevant databases: Medline, PubMed, Google Scholar, Research Gate. The systematic literature review included 12 different types of research. Results: Through a scientific review of the literature, the results of the significance and effectiveness of
various programs of Otago exercises, Tai Chi, and Frenkle exercises in the prevention of falls in people of the third age are presented. The greatest effect is realized in the improvement of static and dynamic balance and the fear of falling. Conclusion: These studies show that different exercise programs have a huge and significant impact on reducing the risk of falls in older people. It is a long-term and continuous method of reducing the risk of
falls in the elderly through exercise. Physical exercise is effective in improving components of balance, lower extremity strength, mobility, and reducing falls and fall-related injuries.
Factors Influencing Consumer Adoption of Mobile Payment Systems in Jambi, Indonesia: A Technology Acceptance Model Approach
Authors: Delvita Juniarsih  , Panji Ulum  , Darmawanto  , Eva Marlina  , Hamirul  , Feri Antoni
Published: October 2024

Mobile payment systems (MPS) are rapidly transforming financial transactions in Indonesia, including in Jambi Province. However, the adoption rate varies significantly. This study investigates the factors influencing consumer adoption of MPS in Jambi, Indonesia, using the Technology Acceptance Model (TAM) as a theoretical framework. A quantitative approach was employed, involving a survey of 300 consumers in Jambi Province. Data were analyzed using Structural Equation Modeling (SEM) to examine the relationships between perceived usefulness, perceived ease of use, social influence, trust, perceived risk, and the intention to use MPS. The findings revealed that perceived usefulness, perceived ease of use, social influence, and trust positively influence the intention to use MPS. Conversely, perceived risk negatively affects adoption intention. This study provides valuable insights for policymakers, financial institutions, and mobile payment providers to promote MPS adoption in Jambi. Strategies should focus on enhancing the perceived usefulness and ease of use of MPS, building trust, leveraging social influence, and mitigating perceived risks.