bluuebunny/crossref_metadata_2025 huggingface dataset:
Thực trạng kiến thức phòng ngừa chuẩn của điều dưỡng, hộ sinh và kỹ thuật viên tại Bệnh viện Hữu Nghị Đa khoa tỉnh Nghệ An năm 2024
Authors: Phạm Thị Giang , Mai Thị Lan Anh , Lê Thị Nhan
Published: October 2024

Mục tiêu: Mô tả thực trạng kiến thức phòng ngừa chuẩn của điều dưỡng, hộ sinh và kỹ thuật viên tại Bệnh viện Hữu Nghị Đa Khoa tỉnh Nghệ An năm 2024 và một số yếu tố liên quan.
Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang có phân tích về kiến thức phòng ngừa chuẩn của 300 điều dưỡng, hộ sinh, kỹ thuật viên. Sử dụng bộ câu hỏi kiến thức được xây dựng dựa trên hướng dẫn về phòng ngừa chuẩn theo quyết định số 3671/QĐ – BYT ngày 27 tháng 9 năm 2012 của Bộ Y tế.
Kết quả: Kiến thức phòng ngừa chuẩn của điều dưỡng, hộ sinh, kỹ thuật viên đạt trung bình 13,6 (± 3,7) điểm. Kiến thức tốt nhất về mục đích sử dụng PPE nhân (95%), kiến thức hạn chế nhất về khái niệm phòng ngừa chuẩn (45,3%). Kiến thức phòng ngừa chuẩn của điều dưỡng-hộ sinh-kỹ thuật viên liên quan có ý nghĩa thống kê với: tuổi, thâm niên công tác, trình độ học vấn, lĩnh vực chuyên môn công tác (p < 0,05).
Kết luận: Kiến thức của điều dưỡng, hộ sinh và kỹ thuật viên tham gia nghiên cứu còn hạn chế. Để nâng cao hiệu quả trong công tác phòng ngừa chuẩn, các cơ sở y tế cần tổ chức các chương trình đào tạo định kỳ nhằm cải thiện kiến thức cho nhóm nhân viên có thâm niên công tác và trình độ học vấn thấp hơn, đồng thời nâng cao nhận thức về việc sử dụng thiết bị bảo hộ cá nhân (PPE) để đảm bảo an toàn và chất lượng chăm sóc người bệnh.
Islamic Values in a Multicultural Society: An Analysis of Parenting and Social Integration of Muslim Minorities
Authors: Shofiatin Ana , Rosodor Suraining
Published: October 2024

This research examines Islamic education parenting and social integration of Muslim minorities in Tanjung Labu Village, Rantau Pulung Sub-district, East Kutai Regency. Using a qualitative method with a case study approach, this research aims to understand the dynamics of Islamic education and social integration strategies in the context of multicultural communities in transmigration areas. Data were collected through participatory observation, in-depth interviews, focus group discussions, and document analysis. The results show that the minority Muslim community in Tanjung Labu Village applies a variety of parenting patterns, from those that tend to be authoritarian in matters of principle to those that are more democratic in other aspects. Social integration efforts are seen in various aspects of life, including education, economy, and culture. Programs such as ‘Friday Taqwa’ in schools and cooperation in farmer groups show positive steps in realizing social integration. However, the research also identified challenges such as the lack of special programs for converts and potential discrimination. The study concludes that efforts to strengthen the social integration of Muslim minorities require a holistic, inclusive, and sustainable approach, involving the active role of the Muslim community and support from various relevant parties. The findings make an important contribution to understanding the complexities of Islamic education and social integration in minority contexts, as well as highlighting the importance of empowering Muslim converts.
Coincidence or consequence? Single coronary artery in a dilated cardiomyopathy case
Authors: Paraschiv Catalina , Paduraru Livia F. , Balanescu Serban M.
Published: September 2024

Single coronary artery is a rare congenital condition which entails one artery to supply blood to the entire myocardium. A case of single coronary artery in a patient diagnosed with tachycardia-induced cardiomyopathy is discussed. The focus of this case is to present the clinical implications of this coronary anomaly.
A study of climate resilience in urban tree species of Peninsular Malaysia
Authors: A. Carr Jamie , Khamis Shamsul , Sivaraj Melissa , Messina Tainan
Published: September 2024

Climate change poses significant challenges to Malaysian cities, including heat stress, which high humidity and the urban heat island effect exacerbate. While trees effectively reduce temperatures and improve microclimates, potential sensitivities to climate change impacts require careful species selection. Experts assessed the resilience of 220 tree species from urban and rural areas of Malaysia using eight criteria, based on a list compiled from four sources. We then categorised the species by sensitivity for four urban landscape types. Saltwater sensitivity had the highest proportion of sensitive species, followed by inundation sensitivity. Considering regional climate projections, planners should prioritise species with low inundation sensitivity. Data availability for saltwater, inundation, and high-temperature sensitivities was limited but adequate for the remaining criteria, with susceptibility to predation, parasitism, or disease, and sensitivity to storm conditions being of concern. Urban planners should integrate these criteria into decision-making to ensure climate-smart urban design. Given that our knowledge about the effects of climate change on tree species will advance and should be documented, we developed an open-collaborative online database that assists stakeholders in selecting suitable species for various sites in Malaysia. Moderators will review submissions to ensure consistent application of criteria and alignment between selected answers and supporting information. Assessors can contribute to quality control by voting for assessments they agree with. Our research emphasises the importance of proactively addressing climate change challenges in urban areas and underscores the value of informed decision-making to enhance the resilience of urban tree populations.
Investigative analysis of the impact of low-level air pollution NO2 on mortality rates among residents due to cardiovascular and cerebrovascular diseases
Authors: Che Zesheng , Cui Xiuqing , Wang Bin , Hui Yanlin , Dai Lan , Cao Xueqin , Wang Chunhong , Shi Tingming
Published: September 2024

Objective: The study aims to assess the influence of low-level atmospheric nitrogen dioxide (NO2) on the mortality risk associated with cardiovascular and cerebrovascular diseases in Enshi City, with the intention of providing a scientific foundation for identifying sensitive populations and devising population health policies. Methods: Data on air pollutant levels, meteorological factors, and mortality rates due to cardiovascular and cerebrovascular diseases among residents of Enshi City were collected from 2015 to 2018. A generalized additive model, based on the Poisson distribution, was employed to analyze the relationship between low-level NO2air pollution and the mortality risk for these diseases. Subgroup analyses were conducted based on age, gender, and season. Results: The average concentrations of key gaseous pollutants in Enshi City from 2015 to 2018 were as follows: NO2 (21.40 μg/m3), sulfur dioxide (SO2, 9.68 μg/m3), carbon monoxide (CO, 0.88 mg/m3), and ozone (O3, 61.21 μg/m3). The analysis of the single-pollutant model indicated that for every 1 μg/m3 increase in NO2 concentration across the total population, the risk of dying from cardiovascular and cerebrovascular diseases on the same day (lag0) rose by 0.33% (95% CI: -0.06% to 0.72%, P > 0.05). Among females, each 1% increase in NO2 concentration was associated with a 0.92% increase (95% CI: 0.26% to 1.56%, P < 0.05) in the risk of mortality from these diseases with a cumulative lag of 1 day (lag01). During the cold season, every 1 μg/m3 increase in NO2 concentration was linked to a 0.62% increase (95% CI: 0.12% to 1.12%, P < 0.05) in the mortality risk for the entire population on the same day (lag0). The two-pollutant model results showed that even after adjusting for other gaseous pollutants (SO2, CO, or O3), the association between NO2 and the mortality risk from cardiovascular and cerebrovascular diseases persisted for women and the entire population during the cold season. Conclusion: In Enshi City, the presence of low NO2 pollution levels is associated with an elevated risk of cardiovascular and cerebrovascular disease mortality among both women and the general population, particularly during the colder months. It is crucial to prioritize the health safeguarding of vulnerable populations in regions with low pollution and during specific seasonal periods.
Analyzing the relationship between air pollution and asthma outpatient visits in Hefei through time series data
Authors: Wu Xiaofeng , Sui Xinmiao , Sun Shu , Cao Jiyu
Published: September 2024

Objective: To examine the correlation between the volume of adult asthma patients seeking outpatient care and air pollution levels at a hospital in Hefei. Methods: Data on the number of asthma outpatients at a Hefei hospital from 2014 to 2020 were gathered, along with corresponding air pollution and meteorological data for the same timeframe. The R statistical software was employed to construct a generalized additive model to assess the lagged effects of air pollution on asthma outpatient numbers. Results: The hospital recorded a total of 7220 asthma outpatients during the study period, with 3104 males and 4116 females, 3798 in the warm season and 3422 in the cold season. The single pollutant model revealed that a 10% increase in SO2 concentration μg/m3 was associated with a 0.74% increase in asthma risk, with the strongest effect observed at lag2. NO2 was found to increase asthma risk by 0.31%, with the most significant impact at lag0. The two-pollutant model indicated that the effect of SO2 combined with NO2 diminished when SO2 was also combined with CO, O3, PM10, and PM2, with an increased post-5 lag effect. Conversely, the effect of NO2 combined with SO2 decreased when NO2 was also combined with CO, PM10, and PM2, with an increased post-5 lag effect. Stratified analysis by season showed that NO2's impact on asthma was greatest at lag0 during the cold season, while SO2's effect was more pronounced in the cold season than in the warm season, with the highest impact at lag2. Gender stratification analysis revealed that the effects of SO2 and NO2 were greater in men than in women. Conclusion: Between 2014 and 2020, an increase in SO2 and NO2 concentrations in Hefei was positively associated with the risk of asthma among outpatients at the hospital, with a noticeable lag effect. This finding underscores the importance of developing targeted preventive strategies to mitigate asthma occurrences and exacerbations.
Analysis of water pollution in Chinese port regions to inform green port development
Authors: He Linlin , Jia Rui , Jiao Yuqi , Liang Yue
Published: September 2024

Water transport has emerged as one of the most significant modes of transportation globally, owing to its high carrying capacity, low transport costs, and minimal energy consumption. As a critical hub for land-water transfer, ports experience frequent interactions between ships and land, leading to substantial discharges of domestic sewage and oily wastewater, as well as suspended pollutants from construction activities. Consequently, water pollution in port areas has become increasingly severe. To implement sustainable development strategies and promote green port initiatives, it is essential to research and address water pollution in these areas. This paper first summarizes the sources and impacts of the main water pollutants associated with port construction and operations. It then discusses the spatial and temporal distribution patterns of these pollutants. Finally, based on a literature review, the author highlights the current state of water pollution in port areas, advocates for the introduction of ecological engineering solutions for wastewater treatment, compares the differences in water pollution prevention plans between domestic and international ports, and identifies the shortcomings and gaps in existing research and prevention efforts related to water pollution in port areas.
Survey of microbial contamination levels of direct drinking water from terminal devices in Yantai City
Authors: Gong Chunbo , Zheng Zhong , Dong Fengguang , Wang Zhaoxia
Published: September 2024

The study aimed to assess the quality and sanitation of direct drinking water from terminal devices collected from various places such as communities, schools, and homes in Yantai City. This research was to support regulations, enhance authorized supervision, and inform consumer choices. 232 samples were randomly gathered in aforementioned places between June to November, 2019. The test of aerobic plate count, Coliforms, and Pseudomonas aeruginosa followed the standard operating procedure provided by Chinese National Food Contamination and Harmful Factors Risk Monitoring Manual in 2019. Findings showed that 84.05% of the samples had aerobic plate counts as main contamination, with Coliforms and Pseudomonas aeruginosa was respectively 3.02% and 7.33%. These results revealed that aerobic plate count was the main contaminant in high-quality drinking water, while Pseudomonas aeruginosa was the main pathogenic bacteria. Overall, 9.48% of the samples exceeded the standard. Family settings had the highest non-compliance rate at 12.68%, followed by schools at 8.97%, and communities at 7.23% by comparing different sources, yet these differences were not statistically significant (χ2 = 1.36, P > 0.05). There was no clear seasonal variation regularity of the detection rate. However, there was clear variation in monthly non-compliance rates. The highest was at 15.00% in November, followed by June at 13.89%, September at 11.76%, October at 6.25%, August at 5.88%, and July at 5.00%. Yet these differences were not statistically significant, either (χ2 = 4.47, P > 0.05). It was notable that some samples exhibited multiple contamination by various indicators. In summary, the study showed widespread contamination of direct drinking water by aerobic plate count, Coliforms and Pseudomonas aeruginosa, with aerobic plate count being the most prevalent issue.
Contamination of water resources as a starting point for socio-scientific activism
Authors: Conceição Teresa , Baptista Mónica , Reis Pedro
Published: September 2024

Science curricula emphasize the need to involve students in civil society issues related to science, highlighting the primacy of learning about the science-technology-society-environment relationship. The objective of this work is to know the students' learning when they get involved in the attempt to solve the problem related to the pollution of the stream near their school. The research methodology is qualitative, interpretative and based on participant observation. Twenty-one students from two 8th grade classes[1] with an alternative curriculum, living in a rural environment in southwestern Portugal, participated in the study. Data were collected through the teacher's diary, written documents and interviews with the students (conducted at the ﬁnal of the study). The results reveal that the positive experiences provided by the radio club gave them confidence and encouraged them to engage in community activism related to the pollution of the local stream. This activism takes the form of a puppet show about sewage treatment. Also, the results show us that activism leads students to the identiﬁcation of the science and technology issues that are at the root of the pollution of the creek, expanding their knowledge about the problem and discussing different perspectives for its solution. In addition, young people recognize that knowledge enables them to inform other members of the community and realize that they have the right to become involved in socio-scientific issues that affect their quality of life.
Quantifying ecological toxicity from real heavy metal co-contamination in site soil
Authors: Ma Zhe , Wang Meie , Jiang Rong , Chen Weiping
Published: September 2024

This summary outlines a significant challenge in ecological risk assessment of contaminated sites: quantitatively evaluating the ecological effects of combined heavy metal pollution in real-world soil. The study proposes a novel quantitative ecological assessment approach that integrates both broad ("top-down") and detailed ("bottom-up") knowledge. This approach involves three key steps: identifying effective biomarkers, pinpointing dominant pollutants, and assessing the combined effects of various exposure types and contaminants. To validate this approach, researchers examined an abandoned electronic waste site in Jiangsu Province using soil microcosms with earthworms. By analyzing biomarkers such as malondialdehyde (MDA), metallothionein (MT), catalase (CAT), superoxide dismutase (SOD), and reduced glutathione (GSH), they found that earthworms accumulated heavy metals in the order of Cd > Cu > Zn > Ni > Pb > Cr. Principal component analysis (PCA) identified GSH, CAT, and MDA as effective biomarkers, with Cd and Zn as the primary contaminants. The study revealed significant linear relationships between biomarker changes and specific heavy metal concentrations in soil (e.g., GSH with total Cd and DTPA-extractable Zn, MDA with DTPA-extractable Cd, and CAT with total Zn and bioaccumulated Zn). The sensitivity of the biomarkers to heavy metal contamination was ranked as GSH > CAT > MDA. Furthermore, the study highlighted complex interactions among different heavy metals, exposure types (e.g., soil vs. bioaccumulated), and biomarkers, emphasizing the need for comprehensive assessments in contaminated site evaluations.
Cellulosic nanomaterials for adsorption of emerging pollutants
Authors: Sulbarán Rangel Belkis Coromoto , Madrigal Olveira Abigail Eloísa , Romero Arellano Víctor Hugo , Guzmán González Carlos Alberto
Published: September 2024

Context: At present, nanotechnology can be used in multiple areas of action which, due to its nature, can be implemented with great versatility, given that many advances in nanotechnology base their studies on how to optimize daily and industrial processes and how to favor the environment. In addition, the manipulation of matter at this level allows the creation of solutions with greater scientific, social and economic impact. For the purposes of this research, laboratory results will be shown using cellulosic nanomaterials for the adsorption of emerging antibiotic-type contaminants. Method: This research was carried out at laboratory level, where cellulose was modified by chemical methods to obtain nanocellulose by oxidation. A characterization of the material obtained by spectroscopy techniques was carried out, and the adsorption of emerging anti-biotic contaminants such as ciprofloxacin. Results: Cellulosic nanomaterials have the potential to be used in tertiary water treatment for the removal of emerging contaminants such as ciprofloxacin. The results show that the cellulosic nanomaterial adsorbs ciprofloxacin by 27 %. Conclusions: Nanocellulose membranes have potential for use in a water purification system; those made only with cellulose showed a lower percentage of contaminant adsorption than membranes with nanocellulose.
Current state of environmental contamination in the Oaxacan Mixtec Region
Authors: Ruiz Vicente Marco Antonio
Published: September 2024

Objective: To present a systematic review of studies that evaluate the impact caused by urban solid waste generated in the Oaxacan Mixtec region. Results: The analysis of the research results consulted in the following databases: Red de Revistas Científicas de América Latina y el Caribe (Redalyc), Scientific Electronic Library Online (Scielo), Dialnet, EBSCO and Consorcio Nacional de Recursos de Información Científica y Tecnológica (CONRICYT), show that pollution is a problem that has been gradually increasing globally, which has led to the presence of foreign organisms and substances that interfere with and damage the health of people, natural resources and the ecological balance; It is worth mentioning that the impact on communities caused by the inadequate generation and management of solid waste significantly alters the ecosystem of the areas surrounding the disposal sites. It is important to note that there is legislation in this area that specifically classifies the different disposal sites and entrusts the municipalities with the integral management of urban solid waste, but this legislation is not correctly applied despite the fact that this problem has become very important in the last two decades in governmental spheres. Conclusions: Mexico faces the challenge of resolving environmental problems in order to reach a level of sustainability and sustainability in the medium term. The generation rates of urban solid waste continue to increase because we live in a society that has drastically modified its consumption habits. The degradation of the environment and natural resources for the Oaxacan Mixtec region is classified in ranges from unstable-critical to critical, causing pressure on natural resources, which is why we must have an adequate management and disposal of municipal solid waste, to achieve this it is necessary to have the support of society, governments and society in general, this synergy is necessary to reduce the extraction of resources used to produce them obtaining economic, social and environmental benefits in the long term for the region.
The use of R code for modeling and simulation of 2-D contaminant migration through a soil for the pulse source
Authors: Türkel Atilla Onat , Çokça Erdal
Published: September 2024

In this study, based on an existing analytical solution for the two-dimensional transport of contaminants in a saturated soil layer, for the pulse source, the R program code was developed. The simulation is used to obtain the profiles of contaminant concentration, for a steady groundwater velocity, as a function of distance from the source and time. The problem is analytically solved by leveraging the similarity between the Gaussian (normal) distribution and contaminant concentration distribution, the development of the analytical model (i.e., solution of partial differential equation) by using this similarity is explained step by step since it may be of interest to researchers. Contaminant propagation is modeled using R software, which helps to understand how contaminants migrate through a saturated soil layer. This approach aids in comprehending the mechanisms and spatial dynamics of contaminant dispersion, facilitating the prediction and management of soil and groundwater contamination. The provided R code can be altered for different parameters and time intervals.
Development of machine learning algorithm for loop-mediated isothermal amplification including influence of temperature
Authors: Endoh Taichi , Sanekata Yuichi , Kayama Kotetsu , Endoh Daiji , Camer Gerry
Published: October 2024

To predict amplification in the Loop-Mediated Isothermal Amplification (LAMP) method, a binary model has been developed. This model assesses whether the combination of partial template binding facilitated by multiple primers aligns with a specific signature indicating amplification. For this model, 1512 settings were adjusted, encompassing variations in the extraction oligomer position from the primer, the oligomer length, the number of allowed mismatched bases, and the stringency of the homology position. The optimal set was determined based on the F1 value at a reaction temperature of 60°C, resulting in a value of 0.58. To implement machine learning by amalgamating multiple models, duplicate models were eliminated through cluster analysis. Machine learning using AutoML was performed on 108 distinct models. Consequently, the F1 values were 0.7119 at a reaction temperature of 60°C and 0.7210 at 68°C. The weak correlation between feature importance and the F1 value of the model alone suggests that machine learning utilizing this model incorporates numerous models to enhance prediction accuracy.
In vivo anti-tumor and anti-metastatic activity of renieramycin M and doxorubicin combination treatments on 4T1 breast cancer murine model
Authors: Acyatan Zildjian , Susana-Guevarra Shalice , Picart Myra Ruth , Belen Eliza , Salvador-Reyes Lilibeth , Concepcion Gisela
Published: October 2024

Breast cancer continues to be a serious global health concern, necessitating novel treatment approaches. This study explores the potential of combination therapies, investigating the combinatorial effects of doxorubicin (Dox) and renieramycin M (RM) in vivo, previously shown to have synergistic effects in vitro. Single drug administrations and combination treatments were tested on in vivo breast cancer murine models using 4T1-injected BALB/c mice. Tumor volume, animal mortality, and clinical toxicity were monitored, and in silico toxicity assessment was performed. Histopathological analyses using hematoxylin and eosin (H&E) staining, and immunohistochemistry utilizing the p63 breast cancer marker were used for validation. The combination treatment of Dox and RM (5 mg/kg + 1 mg/kg) displayed a 46.53% reduction in tumor volume and an 83.63% decrease in observed metastatic infiltration in the liver. Furthermore, the combination treatment of Dox and RM significantly delayed and reduced the clinical signs of toxicity, as revealed by the decline in observed mortality as opposed to animal deaths in single drug treatments. Our study highlights the potential synergism between Dox and RM as combination therapy for breast cancer treatment. These findings provide possible strategies to improved therapies, offering a more effective and less toxic approach to mitigating breast cancer.
Lenvatinib and pembrolizumab versus platinum doublet chemotherapy as second-line therapy for advanced or recurrent endometrial cancer
Authors: Yoneoka Yutaka , Amano Tsukuru , Takahashi Akimasa , Nishimura Hiroki , Deguchi Mari , Yamanaka Hiroyuki , Tanaka Yuji , Tsuji Shunichiro , Murakami Takashi
Published: September 2024

Objective There is no consensus on whether platinum doublet chemotherapy or lenvatinib and pembrolizumab (LEN/PEM) is superior for advanced or recurrent endometrial cancer. Thus, this study aimed to compare the prognosis and adverse events in patients with advanced or recurrent endometrial cancer treated with platinum doublet chemotherapy or LEN/PEM.Methods We retrospectively reviewed the medical records of patients who received platinum doublet chemotherapy or LEN/PEM at our institution for advanced or recurrent endometrial cancer and had a history of platinum-based chemotherapy between January 2013 and August 2023.Results During the study period, 11 regimens were identified in the platinum doublet chemotherapy group, and 11 regimens were identified in the LEN/PEM group. The objective response rates of the platinum doublet chemotherapy and LEN/ PEM groups were 36.4% and 54.5% (P=0.67), respectively. The 6-month progression-free survival (PFS) rates of the platinum doublet chemotherapy and LEN/PEM groups were 27.3% (95% confidence interval [CI], 13.8%-40.7%) and 70.0% (95% CI, 55.5%-84.5%), respectively. The differences were significant between the two groups. Multivariate analyses of histology, prior lines of chemotherapy, platinum-free intervals, and regimens revealed that the LEN/PEM group had significantly better PFS rates.Conclusion Treatment with LEN/PEM resulted in significantly longer PFS than that of treatment with platinum doublet chemotherapy in patients with advanced and recurrent endometrial cancer. However, further large-scale studies are required to validate these findings.
EVALUATING THE SKIN IRRITATION OF CHILI PEPPER NANO GEL ON EXPERIMENTAL RABBIT SKIN
Authors: Đỗ Thị Hằng , Đỗ Văn Dũng , Nguyễn Văn Hưng , Nguyễn Vũ Hùng , Lê Anh Tùng , Hồ Mỹ Dung , Nguyễn Thuỳ Dung , Mai Phương Thanh , Phan Hồng Minh
Published: September 2024

Chili is not only a popular spice in food preparation but is also used as a traditional medicine. In particular, when used topically, the active ingredient called capsaicin in chili peppers helps treat bone and joint pain. Objectives: The study aims to evaluate the local irritation on the healthy skin of rabbits of a nano gel product containing chili fruit extract provided by the Institute of Research and Application for Traditional Pharmaco-Medicine Methods: The study was conducted according to the guidelines of the Vietnam Ministry of Health, ISO 10993-10 and OECD on skin irritation assessment for topical products. Three healthy white New Zealand rabbits were used. Animals were applied gauze which was soaked in nano gel containing chili fruit extract at a dose of 0.5 grams on a healthy skin area 2.5 x 2.5 cm for 4 hours. We evaluated the irritation index including erythema and edema on the skin at 24, 48, and 72 hours after gauze removal. Results: Three rabbits were still healthy, and living normally, there were no signs of erythema and edema on the rabbit's skin, and the irritation indexes were 0 during 72 hours of continuous monitoring. Conclusions:The nano gel containing chili fruit extract applied topically does not irritate healthy rabbit skin.
IMMUNOENHANCEMENT EFFECTS OF THE HERBAL FORMULA ANTI-U200 ON CYCLOPHOSPHAMIDE-INDUCED IMMUNOSUPPRESSION IN MICE
Authors: Pham Thi Van Anh , Bui Thi Huong Thao , Mai Phương Thanh
Published: September 2024

Anti-U200 is an herbal blend comprising Ganoderma lucidum, Hedyotis diffusa, and Scutellaria barbata is known to have immunomodulatory effects. Objectives: We examined the immuno-enhancing effect of this herbal blend on cyclophosphamide (CYP)-induced immunosuppression. Methods: Swiss mice were assigned to one of five groups: the intact control and four CYP treatment groups (one control, one reference (levamisole), and two with the application of Anti-U200 at different dosages; 1.92 or 5.76 capsules/kg). Mice received one of the experimental treatments after being injected with CYP to induce myelosuppression and immunosuppression. Results: Anti-U200 therapy improved lymphoid organ atrophy in histological assessments and ameliorated the CYP-induced decreases in spleen and thymus weights in immunosuppressed animals. It also led to beneficial changes in leucocyte counts and boosted TNF-α and IgM serum levels. Conclusions: We have proven that Anti-U200, a combination of three immunomodulatory herbs, is an efficient immunomodulatory agent that can strengthen the immune system.
NUTRITIONAL STATUS AND SOME RELATED FACTORS IN CHILDREN UNDER 24 MONTHS AT THE GENERAL CLINIC OF HOA BINH PROVINCIAL CENTER FOR DISEASES CONTROL 2023-2024
Authors: Tô Thị Quyên , Phan Thị Minh Ngọc , Phạm Văn P
Published: September 2024

NUTRITIONAL STATUS AND SOME RELATED FACTORS IN CHILDREN
UNDER 24 MONTHS AT THE GENERAL CLINIC
OF HOA BINH PROVINCIAL CENTER FOR DISEASES CONTROL 2023-2024
Enhancing Creativity with M.U.S.I.C.
Authors: Henry Jim
Published: October 2024

Over the past 20 years, the value placed on creativity has dramatically increased, and it has become centrally relevant to education on a global scale. This article explores the many elements involved in the creative process in the hope of providing educators with a working knowledge of how creativity might be enhanced. Recommendations are drawn from the existing literature, and a rationale for a product-oriented definition is provided. The elements that influence creativity are organized into five categories: motivation, uncommon commitment, skill, imagination, and courage: as represented by the acronym M.U.S.I.C. Practical strategies for the classroom are included.
Constraints faced by Chawki rearing Centres in Tamil Nadu
Authors:   Centre for Climate Change and Disaster Management (CCC&DM), Anna University, India, Mithilasri Manickavasagam , M Sabarish ,   Department of Sericulture, Government of Tamil Nadu, India, K Uma ,   Tamil Nadu Agriculture University, Coimbatore, Tamil Nadu, India, S.M Shankar ,   Department of Physics, Don Bosco Arts and Science College, Dharamapuri, India
Published: September 2024

Chawki rearing centers (CRCs) play a pivotal role in the sericulture industry by focusing on the cultivation and rearing of high-quality silkworms, known as chawki. This study investigates the primary constraints faced by CRCs across various operational aspects, including agricultural practices, labor management, technical support, and market dynamics. Key findings reveal significant challenges such as the absence of drought-resistant mulberry varieties, high capital requirements for wages, labor shortages, and inadequate technical guidance. Natural factors like climate change and pest outbreaks further exacerbate these issues, impacting silkworm health and productivity. Marketing constraints, such as price volatility and transportation costs, add to the operational complexities of CRCs. The study underscores the need for coordinated efforts among government agencies, research institutions, and industry stakeholders to address these challenges and enhance the sustainability of chawki rearing in the sericulture sector.
Impact of Leadership and Organisational Culture on Operational Performance in China's Food Processing Small and Medium-sized Enterprises
Authors: Zhu Bingqing , Talib Hayati Habibah Abdul
Published: September 2024

As the global food processing sector becomes increasingly competitive and consumer expectations rise, more and more small and medium-sized enterprises (SMEs) in China are beginning to understand the need for excellent leadership in navigating these challenges and succeeding in the global marketplace. This study, which examines leadership's essential role in these SMEs' operational performance and the moderating and intervening effects of quality and safety cultures, is highly relevant to your field of expertise. The relationship between leadership, operational performance, and quality and safety cultures was examined using the Partial Least Squares (PLS) approach. According to the study, leadership directly influences operational performance and significantly impacts the quality and safety cultures of the firms. Moreover, these cultural contexts have moderating and mediating effects on the connection between operational performance and leadership. These results highlight how crucial it is to have strong leadership and robust quality and safety cultures to promote exceptional operational performance in China's SMEs engaged in food processing.
Pre-Hospital Care and Effect of Cardiopulmonary Resuscitation (CPR) On Survival Rate of Out-Of-Hospital Cardiac Arrest (OHCA) Victims, Telangana (India)
Authors: Husain Amreen Aijaz , Rai Uddipak , Sarkar Amlan Kanti , V Chandrasekhar
Published: October 2024

Introduction: OHCA is among the leading causes of mortality worldwide. India lacks a comprehensive database of cardiac arrests and an efficient emergency medical system. The treatment of cardiac disease has improved, yet the outcomes of OHCA remain poor.
Methods: This is an observational 1-year prospective, single center, cohort study conducted on cohorts of OHCA victims. “Utstein Resuscitation Template” was followed for gathering the information starting location of arrest till the final resuscitation outcome. The information on OHCA patient treatment and current knowledge gaps is the aim of this study.
Results: The study was conducted in the Warangal region of Telangana, India. The research comprised 1167 OHCA patients with a suspected cardiac etiology who were taken to the Mahatma Gandhi Memorial Hospital between June 1, 2022, and June 30, 2023. CPR attempts were recorded. Findings suggested if an individual was aware of the risk factors for CVD, they were more likely to report symptoms before OHCA.
Conclusion: OHCA survival rate can be increased if the chain of survival is maintained by offering awareness and CPR training programs to the general public or bystanders, as well as efficient emergency ambulance services with qualified emergency medical staff.
Prevalence of Depression, Anxiety, Stress and Suicide Ideation Among Undergraduate Medical Students in India: A Systematic Review and Meta-Analysis
Authors: Kaur Harpreet , Gupta Varsha , Garg Aseem , Sangeeta  , Padhi Bijaya Kumar
Published: October 2024

Background: Studies reported significant levels of psychological morbidity from across the globe among undergraduate medical students. Present meta-analysis aimed to provide a most up to date comprehensive insight into the prevalence of depression, stress, anxiety and suicidal ideation among undergraduate medical students in India.
Material and Methods:  A systematic search was conducted in three databases PubMed, Scopus and Google Scholar from July 2023 to August 2023. Quality of included studies (43 studies, N=15557) was assessed using modified Newcastle-Ottawa scale and data was analyzed using MetaXL version 5.3. Pooled estimates with 95% confidence intervals were determined using the random-effects model.
Results: The pooled prevalence of depression, anxiety, stress and suicide ideation was 48% (95% CI: 41-55%) (P 0.000, I2 = 98%), 54% (95% CI 42-58%) (P =0.00, I2 = 98%), 50% (95% CI 45-63%) (P =0.001, I2 = 99%) and 21% (95% CI: 9-35%) (P =0.000, I2 = 98%) respectively. Subgroup analysis showed more females than males students were affected from depression, anxiety, stress and suicide ideation.
Conclusion: High prevalence of psychological disorders in medical students in India emphasize the need for the counselling services to control this morbidity and implement long term policies and programs at institutional level.
PneumoNet: Automated Detection of Pneumonia using Deep Neural Networks from Chest X-Ray Images
Authors: Kadiroğlu Zehra , Deniz Erkan , Kayaoğlu Mazhar , Güldemir Hanifi , Şenyiğit Abdurrahman , Şengür Abdülkadir
Published: September 2024

Pneumonia is a dangerous disease that causes severe inflammation of the air sacs in the lungs. It is one of the infectious diseases with high morbidity and mortality in all age groups worldwide. Chest X-ray (CXR) is a diagnostic and imaging modality widely used in diagnosing pneumonia due to its low dose of ionizing radiation, low cost, and easy accessibility. Many deep learning methods have been proposed in various medical applications to assist clinicians in detecting and diagnosing pneumonia from CXR images. We have proposed a novel PneumoNet using a convolutional neural network (CNN) to detect pneumonia using CXR images accurately. Transformer-based deep learning methods, which have yielded high performance in natural language processing (NLP) problems, have recently attracted the attention of researchers. In this work, we have compared our results obtained using the CNN model with transformer-based architectures. These transformer architectures are vision transformer (ViT), gated multilayer perceptron (gMLP), MLP-mixer, and FNet. In this study, we have used the healthy and pneumonia CXR images from public and private databases to develop the model. Our developed PneumoNet model has yielded the highest accuracy of 96.50% and 94.29% for private and public databases, respectively, in detecting pneumonia accurately from healthy subjects.
PLC Controlled Fuzzy Logic-Based Egg Hatching Machine
Authors: Eltaleb Muhammed , Çelik Hakan
Published: September 2024

In response to the increasing food demand due to the growing global population, this study has designed a fully automated incubator machine based on a Programmable Logic Controller (PLC) to enhance efficiency in the egg production sector. To align with Industry 4.0 technologies, this machine controls temperature and humidity using fuzzy logic, one of the artificial intelligence methods. The incubator is capable of meeting the specific temperature and humidity needs for the incubation processes of various types of bird eggs. It has been tested under different conditions, and its performance has been examined in detail. The analysis results show that the fuzzy logic-based temperature and humidity control systems on the PLC successfully reached the set reference values and maintained them continuously and stably after initial fluctuations. In conclusion, the design and control of an automated incubation machine with a PLC-based fuzzy logic controller were successfully accomplished.
A Practical Approach for Estimating Drag Increase due to Volume Increase in the Center Body of a High-Speed UAV
Authors: Özdemir Uğur
Published: September 2024

High-speed unmanned aerial vehicles are used for many purposes in aviation. High-speed aircraft do not only fly at supersonic speed, but their subsonic flight performance is also important. Aircraft design is an iterative process in which many disciplines work together. The design process is updated by the negotiation of different disciplines. There may be a demand for a body volume increase in the interior design process. The increase in volume can be achieved by the elongation or expansion of the body. A volume increase in the center body causes an increase in drag. The aim of this study is to predict the effect of the elongation or expansion of the center body on drag in a practical way. It is investigated using a structure proposed with MATLAB and DATCOM. The results in both subsonic and supersonic regimes are formalized separately and compared. It is shown that in case of providing the same volume increase in both subsonic and supersonic regimes, the elongation of the aircraft center body causes less drag compared to widening.
Comparison of Fourier and Trigonometric Transform based Multicarrier Modulations for Visible Light Communication
Authors: Çürük Selva Muratoğlu
Published: September 2024

It is predicted that the radio frequency spectrum will be insufficient in the near future due to the increase in wireless data. Visible Light Communication (VLC) is an alternative solution, which promises high speeds. Similar to other wireless communication systems, VLC systems prefer Multicarrier Modulation (MCM), but the signals are converted to be real and unipolar before transmission for optical communication. In this paper, two optical MCM groups that utilize Discrete Fourier Transform (DFT) and Discrete Trigonometric Transform (DTT) are questioned with respect to Bit Error Rate (BER), spectral efficiency and complexity. DFT based techniques use complex mapped signals together with their Hermitian symmetries to obtain real output signals, while DTT based techniques already output real signals when the input signal is real mapped. It is seen that DFT based techniques have lower BERs because of used mapping. DTT based techniques improve spectral efficiency, but they are limited to real mappings with higher error rates. For both transformations, the real signals are made unipolar by adding a bias (DCO-MCM), by asymmetrically clipping (ACO-MCM) or by sending positive and negative values separately (UnO-MCM). It is shown that, adding a dc bias (DCO-MCM) increases BERs, where ACO-MCM and UnO-MCM have close performances with lower BERs.
Variations in Diffusion Coefficients on Equinox Days at Specified Critical Heights of the Ionosphere at the Equator
Authors: Kurt Kadri , Yeşil Ali
Published: September 2024

This study investigates the local time diffusion coefficient for stable and unstable ( , ) states at the equator (00), "the geographical latitude where the first peak of the magnetic equatorial trough in the ionosphere occurs," during the spring and fall equinoxes (March 21 and September 23). The findings show that the diffusion tensor in a steady state is completely real and has a magnitude equal to the speed of light in a steady state. But in the unsteady state, the diffusion tensor consists of two parts, real and imaginary. The diagonal elements of the real part tensor are of the size of the conductivity in the ionosphere and the elements of the imaginary part are of the size of the speed of sound with about the same magnitude. Furthermore, for all assumed conditions, the diffusion elements form the first peak of the magnetic equatorial trough at 6.00 am local time.
Factors Affecting Learners’ Motivation in English Language Education
Authors: Kimly Chenda , Hoeurn Sokha , Roeun Sothunthea , Ron Seihak , Khann Sinath
Published: October 2024

This research investigates the factors influencing undergraduate students' interest in learning English at a public university. A quantitative methodology was used, with 250 students completing a 27-item Likert scale survey. The survey measured motivational factors, concerns, confidence, learning processes, benefits, attitudes, and self-regulation. Participants found it easy to participate because of the university's diverse student population and the researchers' affiliation. Questionnaires were distributed in class, with explanations in both Khmer and English to ensure clarity. The study revealed the impact of intrinsic and extrinsic motivation on English language learning in the Cambodian context. Recommendations are provided to assist educators and policymakers in improving motivation strategies and students' language proficiency for academic success.
Over de excessieve vertrekvergoeding, de 30%-regeling en ja, de transitievergoeding
Authors: Chaoui Chaima
Published: October 2024

Over de excessieve vertrekvergoeding, de 30%-regeling en ja, de transitievergoeding

In deze bijdrage behandelt de auteur de eerder dit jaar verschenen uitspraak van Hof Den Bosch over de berekening van de excessieve vertrekvergoeding bij een werknemer met een 30%-regeling (Hof Den Bosch 21 februari 2024, ECLI:NL:GHSHE:2024:521). De auteur staat stil bij de vraag of de belastingvrije 30%-regeling vergoeding onderdeel is (of zou moeten zijn) van het loonbegrip van artikel 32bb Wet LB 1964. Ook wordt aandacht gevraagd voor de onduidelijkheid rondom de berekening van de transitievergoeding bij werknemers met een 30%-regeling. Naar mening van de auteur is het, op basis van huidige regelgeving, verdedigbaar dat de belastingvrije 30%-regeling vergoeding zou moeten worden meegenomen in de berekeningsgrondslag van de transitievergoeding.
Reflection Of Good Governance in Kutadgu Bilig
Authors: Rasekh Mohammad Salih
Published: September 2024

The Qarakhanid dynasty contributed two significant scientific works to humanity: Yusuf Khas Hajeb's "Kutadgu Bilig" and Mahmud Al-Kashghari's "Diwan Lughat al-Turk." Kutadgu Bilig is an illustrious tome replete with insights on state administration, politics, utopian ideals, philosophy, and science. Moreover, it functions as an educational narrative that retains significant value in contemporary times. This book, authored by the Kagans, imparts teachings that encompass the secrets of knowledge, philosophy, ethics, and societal regulations. Composed a millennium ago, these two volumes, regarded as invaluable artifacts, have endured through the ages. Kutadgu Bilig thoroughly examines the administrative conditions, organizational structure, social hierarchies, and customs of the Qarakhanid period. The book examines politics, state administration, administrative organization, and traditions of the Qarakhanid period through an engaging narrative, informed accounts, and delightful tales.
El profesional de la pedagogía como docente en entornos de educación no formal
Authors: García Aguilera Francisco José , Matas Terrón Antonio , Aguilar Cuenca Diego , Segovia García Nuria
Published: October 2024

Este estudio se enfoca en dilucidar el papel de los pedagogos y las pedagogas en el ámbito de la educación no formal, enfatizando la importancia de sus competencias y habilidades para el desarrollo continuo de los profesionales. Para realizarlo se adoptó un enfoque cuantitativo, distribuyendo un cuestionario a 200 profesionales en activo, de los cuales 102 lo cumplimentaron y fueron finalmente las personas que conformaron la muestra. La investigación se centró en analizar cuál es la modalidad de enseñanza que prefieren, las competencias clave y los desafíos a los que se enfrentan, utilizando métodos de estadística descriptiva para el análisis de datos. Los resultados indican una inclinación por modalidades de enseñanza presenciales, aunque se observa un creciente interés hacia los formatos híbridos. Las competencias digitales, el manejo de metodologías didácticas innovadoras, el diseño de materiales educativos y las habilidades de comunicación emergen como fundamentales. Este estudio contribuye a entender cómo los profesionales de la pedagogía pueden fortalecer su rol en la educación no formal, proponiendo una reflexión sobre la implementación de estrategias específicas para el desarrollo de competencias digitales y metodológicas. La investigación sugiere una dirección para futuros estudios, enfocándose en la evaluación de programas de desarrollo profesional que atiendan a las necesidades identificadas.