bluuebunny/crossref_metadata_2025 huggingface dataset:
Renewable Energies: Economic and Energy Impact in the Context of Increasing the Share of Electric Cars in EU
Authors: Zamfir Andreea-Ileana , Croitoru Elena Oana , Burlacioiu Cristina , Dobrin Cosmin
Published: November 2022

Renewable energies have an essential role in reducing various forms of pollution. The policymakers within the European Union place more and more emphasis on the replacement of internal combustion engine vehicles with electric vehicles in order to reduce emissions. The aim of this research is to analyze the current trends in producing and using renewable energy until 2028 and to estimate the impact of replacing the current internal combustion engine cars with electric cars. The significance of this study emerges from the estimation of the amount of electricity needed to replace current cars with electric cars and if it can be covered from green sources, based on the forecast of green energy until the year 2028. In addition, we also calculate in this study the impact on the public budgets of the European Union member states, as a result of the reduction of excise duties for fuels, following the reduction of their consumption. The research was carried out based on the extensive literature on the subject and data from Eurostat. The data used in this study are from 1990 to 2021. In this research we have used the IBM SPSS application with two of the most used forecasting algorithms: exponential smoothing model and autoregressive integrated moving average (ARIMA), based on the statistical analysis of the historical data. The estimated results showed that the replacement of traditional fuels will lead to an increase of 12.18% for electrical energy, and it could be covered 100% from green sources, if needed, even before 2028. There are many implications of this study for policymakers and the population. The results show that we still need policies to stimulate electricity production from renewable sources. There is a challenge regarding reducing government revenue due to fuel excises, which can be compensated by updating tax policies, with an impact on population and living standards. Furthermore, maintaining and adapting support schemes for electric cars, as well as expanding electric car infrastructure and smart grids are also challenges that need to be addressed by the policymakers and the industry.
Diagnosing Disk-Space Variation in Distribution Power Transformer Windings Using Group Method of Data Handling Artificial Neural Networks
Authors: Elahi Omid , Behkam Reza , Gharehpetian Gevork B. , Mohammadi Fazel
Published: November 2022

Monitoring centers in the smart grid exchange the collected data by sensors and smart meters to monitor the current conditions and performance of electric power components. Distribution Power Transformers (DPTs) have a key role in maintaining the integrity of power flow in the smart grid. Online monitoring of DPTs to detect possible faults can potentially increase the reliability of modern power systems. Mechanical defects of DPTs are the major issues in their proper operation that must be detected in their early stage of occurrence. One of the most effective solutions for diagnosing mechanical defects in DPTs is Frequency Response Analysis (FRA). In this study, an appropriate condition monitoring scheme for DPTs is developed to identify even minor winding defects. Disk-Space Variation (DSV), a common DPT windings fault, is applied to the 20 kV-winding of a 1.6 MVA DPT in various locations and with different severity. Their corresponding frequency responses are then computed, and all four components of the frequency responses, i.e., amplitude, argument, and real and imaginary parts, are evaluated. Different data-driven-based indices are implemented to extract appropriate feature vectors in the preprocessing stage. Group Method of Data Handling (GMDH) Artificial Neural Networks is proposed to assist monitoring centers in interpreting FRA signatures and identifying DPT defects at primary stages. GMDH has a data-dependent structure, which gives high flexibility to modeling nonlinear characteristics of FRA test results with different data sizes. It is demonstrated that the proposed approach is capable of accurately determining the fault location and fault severity. The proposed Artificial Intelligence (AI)-based approach is used to extract essential features from frequency response traces in order to detect the position and degree of Disk-Space Variation (DSV) in the DPT windings. The experimental results verify the effectiveness of the proposed methods in determining the severity and location of DSV defects.
Intelligent Identification of Cavitation State of Centrifugal Pump Based on Support Vector Machine
Authors: He Xiaoke , Song Yu , Wu Kaipeng , Ali Asad , Shen Chunhao , Si Qiaorui
Published: November 2022

In order to perform intelligent identification of the various stages of cavitation development, a micro high-speed centrifugal pump was used as a research object for vibration signal analysis and feature extraction for normal, incipient cavitation, cavitation and severely cavitated operating states of the pump at different temperatures (25 °C, 50 °C and 70 °C), based on support vector machines to classify and identify the eigenvalues in different cavitation states. The results of the study showed that the highest recognition rate of the individual eigenvalues of the time domain signals, followed by time frequency domain signals and finally frequency domain signals, was achieved in the binary classification of whether cavitation occurred or not. In the multi-classification recognition of the cavitation state, the eigenvalues of the time domain signals of the four monitoring points, the time frequency domain signals of the monitoring points in the X-direction of the inlet pipe and the Y-direction of the inlet pipe are combined, and the combined eigenvalues can achieve a multi-classification recognition rate of more than 94% for the cavitation state at different temperatures, which is highly accurate for the recognition of the cavitation state of centrifugal pumps.
Strong Responses of Soil Greenhouse Gas Fluxes to Litter Manipulation in a Boreal Larch Forest, Northeastern China
Authors: Duan Beixing , Xiao Ruihan , Cai Tijiu , Man Xiuling , Ge Zhaoxin , Gao Minglei , Mencuccini Maurizio
Published: November 2022

Alterations in plant litter inputs into the soil are expected to significantly affect soil greenhouse gas (GHG) emissions. However, the influence on boreal forest soils is not clear, given the large amount of accumulated soil organic matter that may buffer the impacts from the input of fresh litter. In this study, we conducted a litter manipulation experiment to explore the effects of the litter layer on soil GHG fluxes in a Dahurian larch (Larix gmelinii) forest ecosystem in northeastern China. Three litter treatments were implemented, namely aboveground litter removal (LR), litter double (LD), and unchanged litter input (CK). The associated microclimate, litter characteristics, and soil properties were also measured. The results showed that this larch forest soil acts as a source of CO2 and N2O but acts as a sink for CH4 for all litter manipulation treatments. LD increased the soil CO2 and N2O fluxes by 15% and 34%, while LR decreased them by 8% and 21%, respectively. However, soil CH4 uptake decreased by 34% in LD treatment and increased by 22% in LR treatment, respectively. Litter manipulation treatments can not only affect soil GHG fluxes directly but also, via their effects on soil MBC, NH4+−N, and NO3−−N content, indirectly affect variations in soil CO2, CH4 and N2O fluxes, respectively. Our study highlights the importance of the plant litter layer in regulating soil GHG between the atmosphere and soil in a Dahurian larch forest ecosystem, especially for litter addition. Considering the natural increase in litter quantity over time, this important regulatory function is essential for an accurate estimation of the role of boreal forests in mitigating future climate change.
Assessing Resilience Components in Maritime Pine Provenances Grown in Common Gardens
Authors: Lisella Concetta , Antonucci Serena , Santopuoli Giovanni , Marchetti Marco , Tognetti Roberto
Published: November 2022

Knowledge acquisition on the response of tree species to drought in the Mediterranean hotspot is an important step to guide adaptation strategies to climate change impacts, e.g., assisted migration. We assessed the resilience components—i.e., resistance, recovery, and resilience—to drought in 2003 in five provenances of maritime pine planted in four common gardens in Sardinia, and analysed the possible influence of climate variables on these indices. The provenances showed differences in growth rate but not in the components of resilience. Among the provenances, Corsica was the most productive, while Tuscany was the least. One of the two provenances from Sardinia (Limbara) showed good performance in terms of tree growth in the comparatively drier site. The resilience components were influenced by prevailing environmental conditions at the common garden sites. In the relatively drier sites, trees showed the lowest resistance but the highest recovery values. However, two sites, which had the lowest stand density, showed the opposite trend during the drought year, probably due to moderate thinning. Predictive models showed different probability in the response of resilience components to climate variables. Resistance and resilience had a similar pattern, both being positively related to temperature, while recovery showed an opposite trend. The models’ results indicate a noticeable adaptation of maritime pine to the drought conditions of Sardinia, though the age factor should be considered as well. Despite only minor differences among provenances being found, environmental conditions and management practices at the common gardens were important in determining tree growth patterns. This study suggests that the provenance of Corsica may provide appropriate material for forest plantations in Mediterranean conditions with mitigation purposes.
Wall-to-Wall Mapping of Forest Biomass and Wood Volume Increment in Italy
Authors: Giannetti Francesca , Chirici Gherardo , Vangi Elia , Corona Piermaria , Maselli Fabio , Chiesi Marta , D’Amico Giovanni , Puletti Nicola
Published: November 2022

Several political initiatives aim to achieve net-zero emissions by the middle of the twenty-first century. In this context, forests are crucial as a carbon sink to store unavoidable emissions. Assessing the carbon sequestration potential of forest ecosystems is pivotal to the availability of accurate forest variable estimates for supporting international reporting and appropriate forest management strategies. Spatially explicit estimates are even more important for Mediterranean countries such as Italy, where the capacity of forests to act as sinks is decreasing due to climate change. This study aimed to develop a spatial approach to obtain high-resolution maps of Italian forest above-ground biomass (ITA-BIO) and current annual volume increment (ITA-CAI), based on remotely sensed and meteorological data. The ITA-BIO estimates were compared with those obtained with two available biomass maps developed in the framework of two international projects (i.e., the Joint Research Center and the European Space Agency biomass maps, namely, JRC-BIO and ESA-BIO). The estimates from ITA-BIO, JRC-BIO, ESA-BIO, and ITA-CAI were compared with the 2nd Italian NFI (INFC) official estimates at regional level (NUT2). The estimates from ITA-BIO are in good agreement with the INFC estimates (R2 = 0.95, mean difference = 3.8 t ha−1), while for JRC-BIO and ESA-BIO, the estimates show R2 of 0.90 and 0.70, respectively, and mean differences of 13.5 and of 21.8 t ha−1 with respect to the INFC estimates. ITA-CAI estimates are also in good agreement with the INFC estimates (R2 = 0.93), even if they tend to be slightly biased. The produced maps are hosted on a web-based forest resources management Decision Support System developed under the project AGRIDIGIT (ForestView) and represent a key element in supporting the new Green Deal in Italy, the European Forest Strategy 2030 and the Italian Forest Strategy.
Multifactorial Analysis of the Axle Load of Truck Sets during the Transport of Sawmill By-Products
Authors: Trzciński Grzegorz , Tymendorf Łukasz
Published: November 2022

The aim of the study was to investigate the actual axle loads of vehicles used for the transport of sawmill by-products, resulting from the total weight of the transport set (GVW) at different times of the year and depending on the type of sets and transported assortment. Sawmill by-product loads were divided into groups: wood chips, sawdust, slabs and recycled wood. The research was carried out at the recipient of the sawmill by-products as well as at the producer. The GVW was determined on the basis of weighing the entire set on a stationary scale at the premises of the companies. The load on the individual axles of high tonnage truck units was measured using Model DINI ARGEO WWSD portable truck scales with a 3590M309 weighing terminal. Almost 230 transports were analyzed. It was shown that the average GVW is 39.25 t for transport sets with a load of 22.44 t of sawmill by-products with the usage of the semi-trailer capacity of 0.85. For all transport sets, the average load on the individual axles range from 6.72 t (axle 5 in a six-axle truck and trailer-TT) to 10.29 t for axle 2 in a truck and semi-trailer (TST), where the highest occurs on axle 2 of the truck (drive axle). The influence of the type of transport set (TST or TT) and the type of the assortments on the axle load is shown, and the existing correlations are at the level of 0.604–0.669 for axles 3–5 in the TST set. The static axle loads of the transport sets for the sawmill by-products and the distribution of the total weight of the set among the axles are different from those for roundwood transport.
Accurate Wound and Lice Detection in Atlantic Salmon Fish Using a Convolutional Neural Network
Authors: Gupta Aditya , Bringsdal Even , Knausgård Kristian Muri , Goodwin Morten
Published: November 2022

The population living in the coastal region relies heavily on fish as a food source due to their vast availability and low cost. This need has given rise to fish farming. Fish farmers and the fishing industry face serious challenges such as lice in the aquaculture ecosystem, wounds due to injuries, early fish maturity, etc. causing millions of fish deaths in the fish aquaculture ecosystem. Several measures, such as cleaner fish and anti-parasite drugs, are utilized to reduce sea lice, but getting rid of them entirely is challenging. This study proposed an image-based machine-learning technique to detect wounds and the presence of lice in the live salmon fish farm ecosystem. A new equally distributed dataset contains fish affected by lice and wounds and healthy fish collected from the fish tanks installed at the Institute of Marine Research, Bergen, Norway. A convolutional neural network is proposed for fish lice and wound detection consisting of 15 convolutional and 5 dense layers. The proposed methodology has a test accuracy of 96.7% compared with established VGG-19 and VGG-16 models, with accuracies of 91.2% and 92.8%, respectively. The model has a low false and true positive rate of 0.011 and 0.956, and 0.0307 and 0.965 for fish having lice and wounds, respectively.
Effect of Probiotic Lactic Acid Bacteria (LAB) on the Quality and Safety of Greek Yogurt
Authors: Yang So-Young , Yoon Ki-Sun
Published: November 2022

Greek yogurt is a strained yogurt with a high protein content that brings nutritional benefits. To enhance the functional benefits of Greek yogurt, Greek yogurt was prepared with various combinations of probiotic lactic acid bacteria (LAB) (Streptococcus thermophilus, Lactobacillus bulgaricus, Lactobacillus gasseri BNR17, and Lactobacillus plantarum HY7714). Effects of probiotic LAB on quality, sensory, and microbiological characteristics of Greek yogurt were then compared. Among samples, Greek yogurt fermented by S. thermophilus and L. bulgaricus showed the highest changes of pH and titratable acidity during 21 d of storage at 4 °C. Greek yogurt fermented with L. plantarum HY7714 had a higher viscosity than other samples. Greek yogurt fermented with S. thermophilus, L. bulgaricus, L. gasseri BNR17, and L. plantarum HY7714 showed superior physicochemical properties and received the highest preference score from sensory evaluation among samples. Overall, the population of enterohaemorrhagic Escherichia coli (EHEC) was more effectively reduced in Greek yogurt fermented with probiotic LAB than in commercial Greek yogurt during storage at 4, 10, and 25 °C. Thus, the addition of L. gasseri BNR17 and L. plantarum HY7714 as starter cultures could enhance the microbial safety of Greek yogurt and sensory acceptance by consumers.
Relativistic Signatures of Flux Eruption Events near Black Holes
Authors: Gelles Zachary , Chatterjee Koushik , Johnson Michael , Ripperda Bart , Liska Matthew
Published: November 2022

Images of supermassive black holes produced using very long baseline interferometry provide a pathway to directly observing effects of a highly curved spacetime, such as a bright “photon ring” that arises from strongly lensed emission. In addition, the emission near supermassive black holes is highly variable, with bright high-energy flares regularly observed. We demonstrate that intrinsic variability can introduce prominent associated changes in the relative brightness of the photon ring. We analyze both semianalytic toy models and GRMHD simulations with magnetic flux eruption events, showing that they each exhibit a characteristic “loop” in the space of relative photon ring brightness versus total flux density. For black holes viewed at high inclination, the relative photon ring brightness can change by an order of magnitude, even with variations in total flux density that are comparatively mild. We show that gravitational lensing, Doppler boosting, and magnetic field structure all significantly affect this feature, and we discuss the prospects for observing it in observations of M87∗ and Sgr A∗ with the next-generation Event Horizon Telescope.
Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel
Authors: Gabusi Elena , Lenzi Enrico , Manferdini Cristina , Dolzani Paolo , Columbaro Marta , Saleh Yasmin , Lisignoli Gina
Published: November 2022

Autophagy is a cellular process that contributes to the maintenance of cell homeostasis through the activation of a specific path, by providing the necessary factors in stressful and physiological situations. Autophagy plays a specific role in chondrocyte differentiation; therefore, we aimed to analyze this process in adipose-derived mesenchymal stromal cells (ASCs) laden in three-dimensional (3D) hydrogel. We analyzed chondrogenic and autophagic markers using molecular biology, immunohistochemistry, and electron microscopy. We demonstrated that ASCs embedded in 3D hydrogel showed an increase expression of typical autophagic markers Beclin 1, LC3, and p62, associated with clear evidence of autophagic vacuoles in the cytoplasm. During ASCs chondrogenic differentiation, we showed that autophagic markers declined their expression and autophagic vesicles were rare, while typical chondrogenic markers collagen type 2, and aggrecan were significantly increased. In line with developmental animal models of cartilage, our data showed that in a 3D hydrogel, ASCs increased their autophagic features. This path is the fundamental prerequisite for the initial phase of differentiation that contributes to fueling the cells with energy and factors necessary for chondrogenic differentiation.
Proteomic Markers in the Muscles and Brain of Pigs Recovered from Hemorrhagic Stroke
Authors: Fedulova Liliya , Vasilevskaya Ekaterina , Tikhonova Olga , Kazieva Laura , Tolmacheva Galina , Makarenko Alexandr
Published: November 2022

(1) Background: Stroke is the leading cause of serious long-term disability. Walking dysfunction and paresis of the upper extremities occurs in more than 80% of people who have had a stroke. (2) Methods: We studied post-genomic markers in biosamples of muscle and brain tissue from animals that underwent intracerebral hematoma and recovered after 42 days. Our purpose was to understand the biological mechanisms associated with recovery from hemorrhagic stroke. We analyzed the peptides formed after trypsinolysis of samples by HPLC-MS, and the results were processed by bioinformatics methods, including the establishment of biochemical relationships (gene to gene) using topological omics databases such as Reactome and KEGG. (3) Results: In the pig brain, unique compounds were identified which are expressed during the recovery period after traumatic injury. These are molecular factors of activated microglia, and they contribute to the functional recovery of neurons and reduce instances of hematoma, edema, and oxidative stress. Complexes of the main binding factors of the neurotrophins involved in the differentiation and survival of nerve cells were found in muscles. (4) Conclusions: A network of gene interactions has been constructed for proteins involved in the regulation of synaptic transmission, in particular presynaptic vesicular and endocytic processes. The presence of transmitters and transporters associated with stimulation of NMDA receptors at neuromuscular junctions shows the relationship between upper motor neurons and neuromuscular junctions.
Open-Access Worldwide Population STR Database Constructed Using High-Coverage Massively Parallel Sequencing Data Obtained from the 1000 Genomes Project
Authors: Frontanilla Tamara Soledad , Valle-Silva Guilherme , Ayala Jesus , Mendes-Junior Celso Teixeira
Published: November 2022

Achieving accurate STR genotyping by using next-generation sequencing data has been challenging. To provide the forensic genetics community with a reliable open-access STR database, we conducted a comprehensive genotyping analysis of a set of STRs of broad forensic interest obtained from 1000 Genome populations. We analyzed 22 STR markers using files of the high-coverage dataset of Phase 3 of the 1000 Genomes Project. We used HipSTR to call genotypes from 2504 samples obtained from 26 populations. We were not able to detect the D21S11 marker. The Hardy-Weinberg equilibrium analysis coupled with a comprehensive analysis of allele frequencies revealed that HipSTR was not able to identify longer alleles, which resulted in heterozygote deficiency. Nevertheless, AMOVA, a clustering analysis that uses STRUCTURE, and a Principal Coordinates Analysis showed a clear-cut separation between the four major ancestries sampled by the 1000 Genomes Consortium. Except for larger Penta D and Penta E alleles, and two very small Penta D alleles (2.2 and 3.2) usually observed in African populations, our analyses revealed that allele frequencies and genotypes offered as an open-access database are consistent and reliable.
Phylogeographic Diversity Analysis of Bipolaris sorokiniana (Sacc.) Shoemaker Causing Spot Blotch Disease in Wheat and Barley
Authors: Sharma Pradeep , Mishra Shefali , Singroha Garima , Kumar Rajan Selva , Singh Sanjay Kumar , Singh Gyanendra Pratap
Published: November 2022

Bipolaris sorokiniana is a fungal pathogen that infects wheat, barley, and other crops, causing spot blotch disease. The disease is most common in humid, warm, wheat-growing regions, with South Asia’s Eastern Gangetic Plains serving as a hotspot. There is very little information known about its genetic variability, demography, and divergence period. The current work is the first to study the phylogeographic patterns of B. sorokiniana isolates obtained from various wheat and barley-growing regions throughout the world, with the goal of elucidating the demographic history and estimating divergence times. In this study, 162 ITS sequences, 18 GAPDH sequences, and 74 TEF-1α sequences from B. sorokiniana obtained from the GenBank, including 21 ITS sequences produced in this study, were used to analyse the phylogeographic pattern of distribution and evolution of B. sorokiniana infecting wheat and barley. The degrees of differentiation among B. sorokiniana sequences from eighteen countries imply the presence of a broad and geographically undifferentiated global population. The study provided forty haplotypes. The H_1 haplotype was identified to be the ancestral haplotype, followed by H_29 and H_27, with H_1 occupying a central position in the median-joining network and being shared by several populations from different continents. The phylogeographic patterns of species based on multi-gene analysis, as well as the predominance of a single haplotype, suggested that human-mediated dispersal may have played a significant role in shaping this pathogen’s population. According to divergence time analysis, haplogroups began at the Plio/Pleistocene boundary.
The Importance of Rift Inheritance in Understanding the Early Collisional Evolution of the Western Alps
Authors: Manatschal Gianreto , Chenin Pauline , Haupert Isabelle , Masini Emmanuel , Frasca Gianluca , Decarlis Alessandro
Published: November 2022

We reassess the architecture and tectonic history of the Western Alps based on recent knowledge developed at rifted margins. First, we replace the main Alpine units of our study area into a synthetic rifted margin template based on diagnostic petrologic, stratigraphic, and structural criteria. We find that some units previously attributed to the internal part of the thick-crusted Briançonnais domain may rather derive from the thin-crusted Prepiemonte hyperextended domain. We assert that the Briançonnais and Prepiemonte domains were separated by a mega-fault scarp. Second, we revisit the Paleogeography of the Alpine Tethys, suggesting that the Briançonnais was a ribbon of little thinned continental crust between two overstepping en-échelon rift basins, namely the Valais domain to the northwest and the Piemonte domain to the southeast. We affirm that this uneven-margin architecture can explain most of the Western Alps’ complexity. In our kinematic model, convergence between Adria and Europe was mainly accommodated by strike-slip movements in the Western Alps until the late Eocene. Orogeny began with the reactivation of the mega-fault scarp between the Briançonnais and Prepiemonte domains, which we name Prepiemonte Basal Thrust. Once hard collision started, the main shortening stepped inboard into the Valais/Subbriançonnais domain along the Penninic Basal Thrust.
Improving Bone Health in Patients with Metastatic Prostate Cancer with the Use of Algorithm-Based Clinical Practice Tool
Authors: Sahu Kamal Kant , Johnson Eric D. , Butler Katerina , Li Haoran , Boucher Kenneth M. , Gupta Sumati
Published: November 2022

Background: The bone health of patients with locally advanced and metastatic prostate cancer is at risk from treatment-related bone density loss and skeletal-related events from metastatic disease in bones. Evidence-based guidelines recommend using denosumab or zoledronic acid at bone metastasis-indicated dosages in the setting of castration-resistant prostate cancer with bone metastases and at the osteoporosis-indicated dosages in the hormone-sensitive setting in patients with a significant risk of fragility fracture. For the concerns of jaw osteonecrosis, a dental evaluation is recommended before starting bone-modifying agents. The literature review suggests a limited evidence-based practice for bone health with prostate cancer in the real world. Both under-treatment and inappropriate dosing of bone remodeling therapies place additional risks to bone health. An incomplete dental work up before starting bone-modifying agents increases the risk of jaw osteonecrosis. Methods: We created an algorithm-based clinical practice tool to minimize the deviation from evidence-based guidelines at our center and provide appropriate bone health care to our patients by ensuring indication-appropriate dosing and dental screening rates. This order set was incorporated into the electronic medical record system for ordering a bone remodeling agent for prostate cancer. The tool prompts the clinicians to follow the appropriate algorithm in a stepwise manner to ensure a pretreatment dental evaluation and use of the correct dosage of drugs. Results: We analyzed the data from Sept 2019 to April 2022 following the incorporation of this tool. 0/35 (0%) patients were placed on inappropriate bone modifying agent dosing, and dental health was addressed in every patient before initiating treatment. We compared the change in the practice of prescribing and noted a significant difference in the clinician’s practice while prescribing denosumab/zoledronic acid before and after implementation of this tool [incorrect dosing: 24/41 vs. 0/35 (p < 0.00001)]; and an improvement in pretreatment dental checkup before and after implementation of the tool was noted to be [missed dental evaluation:12/41 vs. 0/35 (p < 0.00001)]. Conclusion: We found that incorporating an evidence-based algorithm in the order set while prescribing bone remodeling agents significantly improved our institutional clinical practice of indication-appropriate dosing and dental screening rates, and facilitated high-quality, evidence-based care to our patients with prostate cancer.
Factors of Parental Preparation of Children with Mental Illnesses for Their Independent Living after Their Own Death
Authors: Yoshioka-Maeda Kyoko , Fujii Hitoshi , Kageyama Masako , Takamura Soichi
Published: November 2022

Families of children with mental illnesses are often concerned about living in the community after their parents’ death. The cross-sectional study aimed to examine the association between how parents prepare adult children with mental illnesses to live independently after the death of the parent(s). The participants were 1112 members of 46 family support groups for mental illnesses in Tokyo, Japan. The age of the people with mental illness was 40s, and that of their parents was 70s. Logistic regression analysis showed that mothers’ support in daily living, no income or pension for disabled people, staying at home during free time, and parental livelihood being the same as the person with mental illness were factors that were negatively associated with the independent living of people with mental illness. In contrast, parental participation in the family group and creating a system for securing regular living expenses of the person with mental illness were positively associated with independent living. The results suggest that parents need to promote their children’s recovery and prepare them financially by forecasting their independent living after their own death.
Breast Cancer Classification by Using Multi-Headed Convolutional Neural Network Modeling
Authors: Pathan Refat Khan , Alam Fahim Irfan , Yasmin Suraiya , Hamd Zuhal Y. , Aljuaid Hanan , Khandaker Mayeen Uddin , Lau Sian Lun
Published: November 2022

Breast cancer is one of the most widely recognized diseases after skin cancer. Though it can occur in all kinds of people, it is undeniably more common in women. Several analytical techniques, such as Breast MRI, X-ray, Thermography, Mammograms, Ultrasound, etc., are utilized to identify it. In this study, artificial intelligence was used to rapidly detect breast cancer by analyzing ultrasound images from the Breast Ultrasound Images Dataset (BUSI), which consists of three categories: Benign, Malignant, and Normal. The relevant dataset comprises grayscale and masked ultrasound images of diagnosed patients. Validation tests were accomplished for quantitative outcomes utilizing the exhibition measures for each procedure. The proposed framework is discovered to be effective, substantiating outcomes with only raw image evaluation giving a 78.97% test accuracy and masked image evaluation giving 81.02% test precision, which could decrease human errors in the determination cycle. Additionally, our described framework accomplishes higher accuracy after using multi-headed CNN with two processed datasets based on masked and original images, where the accuracy hopped up to 92.31% (±2) with a Mean Squared Error (MSE) loss of 0.05. This work primarily contributes to identifying the usefulness of multi-headed CNN when working with two different types of data inputs. Finally, a web interface has been made to make this model usable for non-technical personals.
De Novo Shoot Development of Tropical Plants: New Insights for Syngonium podophyllum Schott.
Authors: Sand Camelia Sava , Antofie Maria-Mihaela
Published: November 2022

Syngonium podophyllum Schott. cv. ‘White Butterfly’ is recognized as a valuable ornamental plant, and today it is also an important plant species of medicinal interest due to its high contents of phenolic compounds. The purpose of this article is to review the main scientific publications from our laboratory with regard to new scientific achievements dealing with Syngonium species or topics of interest, such as callus formation and further de novo shoot regeneration. The principles and stages necessary to start an industrial-level micropropagation protocol are discussed based on our experience. Different media compositions induced different morphogenetic responses inside the callus—particularly those related to the development of xylematic elements in the organogenetic areas, such as those for rooting, protocorms, and de novo shoot formation. The re-evaluation of old histological images revealed for the first time that xylematic elements are constantly closely positioned to all organogenetic centers, and that their development is closely dependent on the composition of the culture medium. Separate protocorms can be identified only when xylematic tracheary elements are well developed and closely connected to them. The formation of protocorms is strongly dependent on the mineral composition of the culture medium and the balance of plant growth regulators.
Digital Health Information Provided by Public Health Stakeholders on Colorectal Cancer Screening: A Systematic Evaluation
Authors: Hasenpusch Claudia , Faßhauer Henriette , Minow Annemarie , Kannengießer Lena , Hrudey Ilona , Walter Svenja , Stallmann Christoph , Swart Enno , March Stefanie
Published: November 2022

In the federal state of Germany, Saxony-Anhalt, colorectal cancer is the second most frequent cause of death among cancer patients. In order to identify cancer precursors early, colorectal cancer screenings are essential. In this context, health information contributes to informing individuals and imparting them with necessary knowledge to make a decision about (non-)utilization of preventive services. Numerous public health stakeholders (e.g., statutory health insurances) provide health information. This study aimed to evaluate the quality of web-based health information offered by public health stakeholders in Saxony-Anhalt, Germany. A systematic evaluation was used. A search was performed using pre-defined eligibility criteria and search terms. Two independent reviewers assessed the search results based on seven main categories (60 items) developed by the study team in line with the “Guideline Evidence-based Health Information”. In total, 37 materials from 16 different stakeholders were included and yielded a “mediocre quality” (median = 69%). The materials had only partially fulfilled the requirements of national recommendations for evidence-based health information. Access to digital health information regarding colon cancer screening was unsatisfactory, especially for individuals with auditory or visual impairments, due to use of inappropriate communication technologies. Further efforts are required to improve digital health information about colorectal cancer screening.
A Culturally Responsive Trauma-Informed Public Health Emergency Framework for Aboriginal and Torres Strait Islander Communities in Australia, Developed during COVID-19
Authors: Graham Simon , Kamitsis Ilias , Kennedy Michelle , Heris Christina , Bright Tess , Bennetts Shannon K. , Jones Kimberley A , Fiolet Renee , Mohamed Janine , Atkinson Caroline , Chamberlain Catherine
Published: November 2022

The Coronavirus Disease 2019 (COVID-19) pandemic impacted peoples’ livelihoods and mental wellbeing. Aboriginal and Torres Strait Islander peoples in Australia continue to experience intergenerational trauma associated with colonization and may experience trauma-related distress in response to government responses to public health emergencies. We aimed to develop a culturally responsive trauma-informed public health emergency response framework for Aboriginal and Torres Strait Islander peoples. This Aboriginal and Torres Strait Islander-led study involved: (i) a review of trauma-informed public health emergency responses to develop a draft framework (ii) interviews with 110 Aboriginal and Torres Strait Islander parents about how COVID-19 impacted their lives, and (iii) a workshop with 36 stakeholders about pandemic experiences using framework analysis to refine a culturally responsive trauma-informed framework. The framework included: an overarching philosophy (cultural humility, safety and responsiveness); key enablers (local leadership and Eldership); supporting strategies (provision of basic needs and resources, well-functioning social systems, human rights, dignity, choice, justice and ethics, mutuality and collective responsibility, and strengthening of existing systems); interdependent core concepts (safety, transparency, and empowerment, holistic support, connectedness and collaboration, and compassion, protection and caring); and central goals (a sense of security, resilience, wellbeing, self- and collective-efficacy, hope, trust, resilience, and healing from grief and loss).
Spatial–Temporal Patterns of Population Aging in Rural China
Authors: Chen Chan , Li Jie , Huang Jian
Published: November 2022

(1) Background: Population aging has been accelerating in China since the 1990s, and the number of people over 65 reached 190 million in 2020. However, the spatial distribution of the aged is not homogeneous; in rural areas, the aged population accounted for 17.72% of the total population, whereas in urban areas, it accounted for 11.11%, which is 6.61 p.p. less. Therefore, this study aims to examine the spatial heterogeneity and influencing factors of population aging in rural China from 2000 to 2020. (2) Methods: First, Getis–Ord Gi* was used to analyze the spatial clustering of the aged population in rural China. Then, standard deviational ellipse was used to characterize the temporal trend of the spatial clustering of population aging in rural China. Finally, potential influencing factors that could have contributed to the spatial–temporal patterns were analyzed using a novel spatial statistical package “Geographical Detector”. (3) Results: (a). Aging in rural populations increased and occurred throughout China from 2000 to 2020. (b). The spatial patterns of aging in China are roughly divided by the Hu Line, which is the population density boundary of China. (c). The mean center of the aged population tended to orient around a northeast-to-southwest major axis over the past 20 years, contrary to the internal migration pattern that flows from north to south. (d). The population age structure, longevity rate, and fertility rate were the predominant factors of aging in rural areas. (4) Conclusions: As the aged population is rapidly increasing in rural areas in China in a spatially heterogeneous fashion, governments and private sectors need to collaborate to alleviate the problem.
Use of Information and Communications Technology in Family Services and Its Perceived Benefits amid the COVID-19 Pandemic in Hong Kong—Jockey Club SMART Family-Link Project
Authors: Ho Hilary Pui-Yee , Lai Agnes Yuen-Kwan , Kwok Ricky Yu-Kwong , Kwok Tai-On , Chow Edward , Yip Teresa , Tang Wai-Yan , Leung Kam-Wing , Lam Eliza , Lam Kam-Yin , Tsui Terry Shuk-Yin , Lok Wai-Fong , Yam Pui-Wah , Wong Shuk-Fong , Wong Chiu-Man , Cham Kerin Kwok-Wing , Wong Bonny Yee-Man , Ho Sai-Yin , Wang Man-Ping , Lam Tai-Hing
Published: November 2022

Introduction: We examined information and communications technology (ICT) use in family services and its perceived benefits and barriers amid the COVID-19 pandemic in Hong Kong. Methods: We invited all family service social workers of 12 NGOs to complete an anonymous online questionnaire in May 2020 (Part A) and a management representative from each NGO to provide written feedback on ICT use in January 2021 (Part B). Results: In Part A, of 255 respondents (response rate: 67.3%), perceived ICT use in conducting programmes, groups, casework and preventive family programmes showed net increases of 33.9–54.5%; perceived ICT use in different work processes showed net increases of 18.8–48.6%. The three most common perceived benefits were “providing another option to service users” (74.2%), “more convenient service” (60.2%) and “maintaining normal service” (59.7%). In Part B, 12 management representatives consistently reported positive impacts of ICT use on family services. They shared actionable strategies (e.g., ICT skill-related training) and concerns about data privacy and management. Conclusions: ICT use in family services markedly increased amid the COVID-19 pandemic in Hong Kong. It helped make the services more accessible especially when the pandemic restricted face-to-face services.
Assessment of the Best FEA Failure Criteria (Part II): Investigation of the Biomechanical Behavior of Dental Pulp and Apical-Neuro-Vascular Bundle in Intact and Reduced Periodontium
Authors: Moga Radu Andrei , Buru Stefan Marius , Olteanu Cristian Doru
Published: November 2022

The aim of this study was to biomechanically assess the behavior of apical neuro-vascular bundles (NVB) and dental pulp employing Tresca, Von Mises, Pressure, S1 and S3 failure criterions in a gradual periodontal breakdown under orthodontic movements. Additionally, it was to assess the accuracy of failure criteria, correlation with the maximum hydrostatic pressure (MHP), and the amount of force safe for reduced periodontium. Based on cone-beam computed tomography, 81 3D models of the second lower premolar were subjected to 0.5 N of intrusion, extrusion, rotation, tipping, and translation. A Finite Elements Analysis (FEA) was performed. In intact and reduced periodontium apical NVB, stress (predominant in all criteria) was significantly higher than dental pulp stress, but lower than MHP. VM and Tresca displayed identical results, with added pulpal stress in translation and rotation. S1, S3 and Pressure showed stress in the apical NVB area. 0.5 N seems safe up to 8 mm periodontal breakdown. A clear difference between failure criteria for dental pulp and apical NVB cannot be proved based only on the correlation quantitative results-MHP. Tresca and VM (adequate for ductile materials) showed equivalent results with the lowest amounts of stress. The employed failure criteria must be selected based on the type of material to be analyzed.
Prevalence of Dysexecutive Symptoms in High School Students during the COVID-19 Pandemic
Authors: Cervantes-Cardona Guillermo Alonso , Nápoles-Echauri Adriana , Alonso-Estrella Nicolas , Hernández-Mora Francisco Javier , Cervantes-Pérez Enrique , Cervantes-Guevara Gabino , García-Reyna Benjamín , Barbosa-Camacho Francisco José , López-Bernal Noelia Esthela , Chejfec-Ciociano Jonathan Matías , Fuentes-Orozco Clotilde , Cueto-Valadez Tania Abigail , Cueto-Valadez Andrea Estefanía , Brancaccio-Pérez Irma Valeria , Guzmán-Ruvalcaba Mario Jesús , Vega-Gastelum Jesús Oswaldo , González-Ojeda Alejandro
Published: November 2022

This is an observational cross-sectional study designed to ascertain the prevalence and severity of dysexecutive symptoms in high school students during the COVID-19 pandemic. The validated Spanish version of the Dysexecutive Questionnaire (DEX) was used. A total of 2396 participants aged 14–22 years were included. Our sample yielded a mean DEX scale score of 28.14 ± 17.42. By the DEX classification, 889 (37.1%) students achieved optimal scores, 384 (16%) reported mild dysexecutive symptoms, 316 (13.2%) reported moderate dysexecutive symptoms, and 807 (33.7%) reported strong dysexecutive symptoms. We found a significant difference between those with and those without employed mothers, with the former scoring higher (p = 0.004), the same as those with both parents employed (p = 0.004). Adolescents face emotional susceptibility and changes in their family, social, and educational environment related to isolation, resulting in altered emotional responses and social interaction.
Study of the Psychometric Properties of the Spanish Version of the Measure of Moral Distress for Health Care Professionals (MMD-HP-SPA)
Authors: Girela-López Eloy , Beltran-Aroca Cristina M. , Boceta-Osuna Jaime , Aguilera-Lopez Dolores , Gomez-Carranza Alejandro , García-Linares Miguel , Llergo-Muñoz Antonio , Romero-Saldaña Manuel
Published: November 2022

Background: The early detection of moral distress requires a validated and reliable instrument. The aim of this study was to carry out an advanced analysis of the psychometric properties of the moral distress scale for health professionals (MMD-HP-SPA) by performing a validation of the construct and its internal and external reliability. Methods: We performed a multicentre cross-sectional study in health professionals belonging to the Andalusian public health system. Construct validity was performed by exploratory (n = 300) and confirmatory (n = 275) factor analysis (EFA/CFA) in different subgroups; we also analysed the internal consistency and temporal reliability of the scale. Results: 384 doctors and 191 nurses took part in the survey. The overall mean for moral distress was 128.5 (SD = 70.9), 95% CI [122.7–134.3], and it was higher in nurses at 140.5 (SD = 74.9) than in doctors at 122.5 (SD = 68.1), F = 8.37 p < 0.01. The EFA produced a model of five components which accounted for 54.8% of the variance of the model. The CFA achieved a goodness of fit of Chi2 = 972.4; AIC = 1144.3; RMSEA = 0.086; CFI = 0.844; TLI = 0.828; NFI = 0.785. Conclusions: The MMD-HP-SPA scale has solid construct validity, excellent internal consistency, optimal temporal reliability, and underlying dimensions which effectively explore the causes of moral distress in health professionals, thus guaranteeing its use in hospital and community settings.
The Influence of Subjective Socioeconomic Status on Life Satisfaction: The Chain Mediating Role of Social Equity and Social Trust
Authors: Ren Zirong , Yue Guoan , Xiao Weilong , Fan Qinghui
Published: November 2022

Life satisfaction is significantly influenced by social capital, a key sociological term that links people to their social surroundings. Through a survey of 17,217 Chinese residents, this study investigated the probable processes of how subjective socioeconomic status affects life satisfaction within the framework of social capital. The results indicate that there is a positive correlation between subjective socioeconomic status and life satisfaction. Subjective socioeconomic status influences citizens’ life satisfaction not only through the independent mediating effects of perceived social equity and social trust, but also through the chain mediation of perceived social equity and social trust. This research advances our knowledge of the mechanisms behind the association between subjective socioeconomic status and life satisfaction. In improving citizens’ life satisfaction, we should not only provide sufficient subjective socioeconomic status to improve it, but also focus on the improvement of their social equity perceptions and social trust.