bluuebunny/crossref_metadata_2025 huggingface dataset:
Isolation and structure elucidation of antioxidative compounds from Descurainia sophia (L.) Webb ex Prant.
Authors: Purevdorj Erdenetsogt , Nomin Munkhbat , Nomuun Tsevegsuren , Chunsriimyatav Ganbaatar , Sarangerel Oidovsambuu
Published: February 2025

Chemical composition of the ethanolic extract from the aerial parts of Descurainia sophia (L.) Webb ex Prant. growing in Mongolia has been evaluated in this study. Dibenzylbutyrolactone derivative arctigenin (1), its glucoside derivative arctiin (2), benzofurane derivative monoterpene lactone loliolide (3) and furocoumarine derivative xantotoxine (4) were identified by mass spectrometry, 1H, 13C and 2D NMR techniques. Notably, loliolide was identified in this species for the first time. The antioxidant activity of the isolated compounds was evaluated through DPPH, ABTS⁺ radicals scavenging, and Fe³⁺ ion reduction assays. Among the compounds, arctigenin showed the most potent antioxidative effect (DPPH radical IC50: 45.12±0.39 μg/mL; ABTS+radical IC50: 36.19±0.67 μg/mL; FRAP value: 783.17±5.02 μM/L), while loliolide and xantotoxine showed moderate antioxidative effects. These findings suggest that arctigenin, a potent antioxidant and the major component of the extract, highlights the potential of Descurainia sophia (L.) Webb ex Prant. as a valuable source for antioxidant products.
Софийн борбут (Descurainia sophia (L.) Webb ex Prant.) ургамлын антиоксидант идэвхт нэгдлийн бүтцийн судалгаа
Монгол оронд ургадаг Софийн борбут (Descurainia sophia (L.) Webb ex Prant.) ургамлын газрын дээд хэсгийн химийн бүрэлдэхүүнийг судалж, түүнд зонхилон агуулагддаг дибензилбутиролактон лигнаны уламжлалын арктигенин (1) болон арктиин (2), монотерпений лактон, бензофураны уламжлалын лолиолид (3), фурокумарины уламжлалын ксантотоксин (4) гэсэн нэгдлүүдийг ялган, молекулын бүтэц байгууламжийг физик, химийн шинж чанар болон спекртоскопын аргуудаар тогтоон баталгаажуулав. Эдгээрээс лолиолидыг тухайн зүйл ургамлаас анх удаа ялгав. Цэврээр ялгасан дээрх нэгдлүүдийн антиоксидант идэвхийг 2,2-дифенил-2-пикрилгидразил (DPPH) чөлөөт радикал, 2,2’- азино-бис(3-этилбензотиазолин-6-сульфоны хүчил) (ABTS+ ) катион радикал зайлуулах болон Fe3+ ионыг ангижруулах (FRAP) аргуудаар эерэг стандарттай харьцуулан тодорхойлов. Судалгааны дүнд арктигенин хамгийн сайн идэвхтэй (DPPH радикал IC50, 45.12±0.39 мкг/мл; ABTS+ радикал 36.19±0.67 мкг/мл, FRAP утга 783.17±5.02 мкМ/л) байсан бол лолиолид ба ксантотоксин дундаж идэвхтэй, арктиин идэвхгүй байв. Энэхүү судалгаагаар Софийн борбут ургамлын газрын дээд хэсэгт хүчтэй антиоксидант идэвхтэй арктигенин их хэмжээтэй агуулагдаж байгааг тогтоосон ба цаашид түүнээс исэлдэлтийн стрессээс үүдэлтэй өвчнөөс сэргийлэх антиоксидант идэвхтэй бүтээгдэхүүн хөгжүүлэх боломжтой байна.
Түлхүүр үг: Софийн борбут, лигнан, монотерпен, кумарин, DPPH, ABTS, FRAP
Changes and Patterns in Mongolia-Russia Trade
Authors: Avirmed Davaasuren
Published: February 2025

This article examines the historical and contemporary trends in Mongolia-Russia trade, their patterns, and the objective factors influencing them. It also analyzes the impact of the COVID-19 pandemic on the overall dynamics of Mongolia’s export potential and the quantity and value of key imported goods. The article explores the structure of Mongolia’s exports and imports, the role of regions such as Irkutsk Oblast, the Republic of Buryatia, Altai Krai, and Krasnoyarsk Krai in Mongolia-Russia border trade, as well as changes in trade relations between directly adjacent Russian regions and those without direct borders with Mongolia. Additionally, it highlights the specialization and diversification of certain types of goods in border trade between these regions.
Монгол-Оросын худалдаанд гарч буй өөрчлөлтүүд ба тэдгээрийн зүй тогтол
Хураангуй: Энэхүү өгүүлэлд Монгол, Оросын худалдааны түүхэн ба өнөө цагийн чиг хандлага, түүний зүй тогтол, нөлөөлж буй объектив хүчин зүйлс, Монгол Улсын экспортын чадавхи болон импортын гол нэр төрөл барааны тоо хэмжээ ба үнийн дүнгийн ерөнхий динамикт Ковид-19 цар тахалын үзүүлсэн нөлөө, Монгол Улсын экспорт болон импортын барааны бүтэц, Монгол, Оросын хил орчмын худалдаанд Эрхүү муж, Буриад Улс, Алтайн болон Красноярскийн хязгаар зэрэг субъектүүдийн гүйцэтгэж байгаа үүрэг, Монгол Улстай шууд залгаа хиллэдэг субъектүүд ба шууд хиллэдэггүй субъектүүдтэй хийж байгаа худалдаан дахь харьцааны өөрчлөлт, хил орчмын худалдаан дахь субъектүүдийн тодорхой төрлийн бараан дээр дагнаж, төрөлжсөн байдлыг бичсэн.
Түлхүүр үгс: Монгол, Орос, худалдаа, экспорт, импорт, жонш, газрын тос, эрчим хүч, мах махан бүтээгдэхүүн, хүнсний бүтээгдэхүүн, хил орчмын худалдаа гэх мэт.
Distribución urbana y percepciones de la vulnerabilidad en Madrid (2001-2016). Contrastando el proceso de desestabilización de los estables ante la gran recesión de 2008
Authors: Echaves García Carlos , Barañano Cid Margarita , Echaves García Antonio
Published: February 2025

La vulnerabilidad es un campo habitual de investigación sociológica, pero los debates sobre su naturaleza y la población que la conforma se renuevan con la crisis de 2008. En dicho contexto proliferan investigaciones que retoman la pertinencia analítica del proceso de desestabilización de los estables, enfoque según el cual los choques financieros estructurales generan la expansión de riesgos y vulnerabilidades, así como un perfil cada vez más heterogéneo de sus protagonistas. El objetivo del presente artículo es precisamente contrastar la validez de esta perspectiva ante los efectos de la pasada gran recesión, mediante una propuesta de integración metodológica en la ciudad de Madrid. Cuantitativamente, se describe y se cartografía por barrios la distribución y la evolución de un índice sintético de vulnerabilidad socioeconómica, construido a través de los censos de población y viviendas de 2001 y 2011 publicados por el INE (antes de y durante la recesión). Cualitativamente, se analiza el significado de esta vulnerabilidad tomando de referencia percepciones que, derivadas de las tipologías poblacionales obtenidas, emergen de reuniones de grupo y de entrevistas semiestructuradas realizadas en el año 2016 (después de la recesión). Los resultados muestran una distribución urbana de la vulnerabilidad concordante con asimetrías previamente existentes y sin variaciones relevantes en el periodo intercensal estudiado. También evidencian la existencia de vulnerabilidades percibidas relacionales que convergen con esta geografía clásica de la desigualdad. Las conclusiones señalan que la vulnerabilidad es una probabilidad acusadamente estratificada y un estado propio de los habituales colectivos en desventaja, a diferencia del supuesto central de la desestabilización de los estables.
Technoethics in Speculative Fiction: Analyzing the Ethical Implications of Cloning and Artificial Consciousness in Matthew FitzSimmons' Constance
Authors: Ahmad Faiqa
Published: February 2025

This research study focuses on the ethical dimensions of human cloning and artificial consciousness in the novel Constance by Matthew FitzSimmons, reviewing it through the technoethics framework. Embedding it in "long-range effects" presented by Hans Jonas, Karl-Otto Apel's discourse on ethical responsibility, supplemented by Vittorio Naess' ecological ethics, the study makes a comprehensive evaluation of the identity, autonomy, and the moral risks in advancing biotechnologies. The protagonist, Constance D'Arcy, a human clone who grapples with her fragmented memories, epitomizes the personal crises such technologies induce in clone-human beings. Her struggle, in the backdrop of corporate dominance of Palingenesis on cloning technologies, highlights the dilemmas of the clones about their autonomy, personhood, and social acceptance, reflecting contemporaneous dialectics revolving around the ethical integration of technological "others." The study also emphasizes the role of sci-fi in critiquing social, individual and environmental repercussions of technologies, advocating for the placement of ethical limitations and inclusivity. Although it fills the major gap in current scholarship by offering a focused analysis of the moral, social, and ecological implications of cloning for human beings, it also aims to be a suggestive study for the Pakistani literary criticism landscape, situating English fiction as a literary vehicle highlighting the moral challenges arising out of technological intervention in human affairs, workspace and relationships and specific impacts on identity and society at large for critiques.
Climate Change, Environmental Constitutionalism, Right to Life, and the inclusion of Article 9A to the Constitution through the 26th Constitutional Amendment
Authors: Rajper Shakeel Ahmed , Khuhro Mujeeb Rehman , Iftikhar Erum
Published: February 2025

Pakistan's geographic position, social standing, and capacity for climate change adaptation make it one of the globe's most climate-vulnerable nations. Pakistan is unswervingly placed as one of the nations most susceptible to the effects of climate change by the global climate risk index. This paper explores the intricate correlation between climate change, environmental constitutionalism, and article 9a, added to Pakistan's 26th constitutional amendment. It introduces the constitutional development of environmental protection in Pakistan, judicial interpretations of Article 9 on the 'right to life,' and arguments for the need for recognition of rights over the environment. Using the method of comparing legal systems, it displays the shortcomings of Pakistan's governors and explains how Article 9a can become a key to creating sustainable development, protecting endangered populations, and making Pakistan the leader of environmental justice in South Asia. Thus, the research finds that in order to realize the amendment’s potential to bring change and to align Pakistan to international environmental standards, much stronger implementation is required.
Preparing Faculty Resources for Adopting Open Book Exams at a Liberal Art University in Pakistan
Authors: Raza Mehwish , Gavrishyk Ekaterina
Published: February 2025

This paper provides insights into the journey of a liberal arts university in Pakistan towards adopting online or remote Open-Book Examination (OBE) as an attempt to shift from conventional examination to foster deeper learning, critical thinking, and knowledge application skills among undergraduate students. This journey encompassed the creation of a twelve-member Community of Practice (CoP) involving diverse stakeholders representing the full spectrum of university community including faculty, students, leadership, and administrative departments. After a series of regulated meetings, the CoP collaboratively developed assistive resources for the faculty to be able to plan for, prepare, and implement OBE. This initiative was housed at the Center for Learning and Teaching (CLT), a hub of pedagogic innovation and excellence. The OBE resources were disseminated to all faculty through the webpage. These resources are available for viewership beyond the institutional community and serve as a guide for faculty in Higher Education willing to adopt the OBE approach. The paper also unpacks some key attributes of OBE and sets a way forward for capacity building in low-resourced institutes.
Social Loafing and the Healthcare Team
Authors: Hills Laura
Published: February 2025

We’ve all encountered employees who put in less effort and allow others to take up the slack. These “social loafers” can create a host of problems for your healthcare team and the bottom line. This article defines and describes social loafing and provides a brief history of this interesting social psychology phenomenon. It explains what causes social loafing and describes work environments where it is more likely to occur. It also explores how culture, gender, and other individual factors influence social loafing. This article then profiles social loafers by type and describes how social loafing affects team performance. Most importantly, this article provides 12 strategies that prevent social loafing and suggests how to identify social loafers who may be flying under the radar. It offers readers techniques for managing social loafers and clarifies the difference between healthy socializing and social loafing. Finally, this article provides 35 sample questions readers can use to administer a social loafing survey to their employees.
Analysis of Motivation, Competence, Compensation and Work Discipline: Their Influence on Performance Moderated by Employee Career Development (Study at Samarinda City Secretariat)
Authors: Nufuf Galuh Hayatun , Rachman Marjoni , Ruliana Titin
Published: February 2025

This study aims to analyze the influence of motivation, competence, compensation, and work discipline on employee performance through career development at the Secretariat of Samarinda City. The theoretical framework integrates human resource management principles emphasizing operational efficiency, employee empowerment, and sustainable career growth. A quantitative research method was employed, involving 339 employees from various departments within the Secretariat as the study population. Data collection utilized structured questionnaires, and analysis was conducted using Structural Equation Modeling (SEM) with Partial Least Square (PLS) software. The study focused on relationships among independent variables (motivation, competence, compensation, and work discipline), the mediating variable (career development), and the dependent variable (employee performance). Findings indicate that motivation, competence, and compensation significantly affect career development and employee performance, while work discipline impacts performance directly but not significantly through career development. Career development was also found to have a significant positive effect on employee performance. The research highlights the necessity of structured career development programs and effective HR management strategies to enhance employee outcomes.
Foreign investments and the future of the real estate market in Georgia
Authors:   Grigol Robakidze University, Gadelia Natia
Published: February 2025

Georgia's real estate market has experienced significant growth in recent years, largely driven by an increase in foreign direct investment (FDI). This study examines the role of foreign investment in shaping the real estate market, highlighting their contribution to market development, property value appreciation, and infrastructure improvement. The article examines how Georgia's evolving regulatory framework affects investor confidence and market stability, addressing both the benefits and potential risks associated with heavy reliance on external capital. Key challenges, including market volatility, regulatory barriers, and overreliance on low-tech industries, are explored along with the growing need for investment in education and high-tech industries. By analyzing recent trends and forecasting future developments, this article provides a comprehensive overview of the drivers of foreign investment in Georgia's real estate sector. The findings confirm that FDI plays a critical role in market modernization, with its long-term success dependent on a stable regulatory environment and strategic investments.
A Dengue no Brasil com ênfase nos aspectos raciais
Authors: Luz Renan Vitor de Almeida , Pereira Vitória Gazola , Florentino Gisele Cristina Gomes , Souza Yasmin Soares , Chaves Adriano Aparecido Bezerra , Moura Roudom Ferreira
Published: February 2025

Introdução: A dengue é uma doença febril, aguda e com grande potencial de evoluir para quadros graves. Originada por um arbovírus, é transmitida principalmente pelo mosquito Aedes aegypt. Objetivo: Descrever o perfil epidemiológico da dengue no Brasil com ênfase nos aspectos raciais. Método: Estudo ecológico descritivo. Os dados foram obtidos do Sistema de Informação de Agravos de Notificação, envolvendo as notificações de casos prováveis de dengue no Brasil entre os anos de 2014 e 2021. Resultados: Os dados mostram que os anos de 2015 e 2019 foram marcados por epidemias significativas de dengue no Brasil, entretanto foi identificado limitação na pesquisa, no que diz respeito ao não preenchimento do campo “raça/cor” em grande parte das notificações. Conclusão: O estudo constata que a população negra foi a mais impactada durante a epidemia de 2019. No entanto, a ausência do preenchimento do campo "raça/cor" nas notificações limitou uma análise mais aprofundada em outros cenários. São necessárias estratégias mais inclusivas e assertivas a respeito da coleta de dados e preenchimento do campo “raça/cor” das notificações.
Dos princípios à prática: gestão da qualidade em pesquisas biomédica
Authors: Fernandez Saada Lima Chequer , Nunes Nelson Mendes , Almeida Renata de Souza , Hodel Katharine Valéria Saraiva , Machado Bruna Aparecida Souza
Published: February 2025

A gestão da qualidade na pesquisa biomédica é conduzida por um conjunto de práticas sistemáticas que buscam garantir a integridade, reprodutibilidade e confiabilidade dos estudos. Fundamentada em normas, auditorias e boas práticas, essa abordagem visa atender às exigências regulatórias e fortalecer a credibilidade científica, assegurando que os resultados obtidos sejam confiáveis. Além de contribuir para a geração de evidências sólidas, a gestão da qualidade desempenha um papel significativo na construção da confiança pública e no avanço sustentável da ciência, alinhando inovação e disseminação do conhecimento. Este estudo investiga a aplicação da gestão da qualidade na pesquisa biomédica com base em uma análise de artigos publicados entre 2017 e 2021. O método utilizado foi estruturado em três etapas principais: identificação, seleção e avaliação. A análise incluiu a triagem inicial de 69 artigos, resultando na avaliação final de 12 estudos que destacam boas práticas, como auditorias, reprodutibilidade e conformidade com normas. Os resultados indicam que a adoção de práticas responsáveis, apoiadas por lideranças, promove a confiança pública e o desenvolvimento sustentável da ciência na área biomédica.
Desenvolvimento de competências em cursos de administração: um estudo sobre a formação de gestores locais
Authors: Siqueira Wender Rodrigues de , Costa Brener Elias da , Freitas Leonardo Sousa de , Sucupira Grazielle Isabele Cristina Silva , Silva Janice Rodrigues da , Filho William Koga Silva , Júnior Elisiário Borges
Published: February 2025

A formação de gestores locais exige que os cursos de Administração promovam o desenvolvimento de competências alinhadas às exigências do mercado. Este estudo analisa como as ementas dos cursos de Administração de duas Instituições de Ensino Superior (IES) de uma cidade do interior contribuem para essa formação. A pesquisa é caracterizada como descritiva e aplicada, estruturada como estudo de caso, com análise de conteúdo das ementas. A categorização das competências seguiu o modelo de Sousa e Valadão Júnior (2011), classificando-as em cinco grupos: Gestão de Pessoas, Idioma e Cultura, Relações Hierárquicas, Gestão de Stakeholders e Gestão de Negócios. Os resultados indicam que as competências mais frequentes foram visão estratégica, coordenação de trabalho em equipe e desenvolvedor de pessoas, embora apenas a primeira esteja prevista nas Diretrizes Curriculares Nacionais (DCNs). Além disso, não foram identificadas ocorrências da categoria “aspectos locais”, sugerindo que as ementas analisadas priorizam abordagens globais em detrimento das especificidades regionais. A ausência de conteúdos contextualizados reforça a necessidade de adaptação curricular para alinhar a formação às demandas dos gestores locais. O estudo conclui que, embora os cursos de Administração apresentem esforços na inserção de competências, há um desalinhamento entre as diretrizes curriculares e a prática educacional. Pesquisas futuras podem ampliar a análise para outras regiões e tipos de instituições, aprofundando a compreensão sobre o desenvolvimento de competências na formação do administrador.
Políticas públicas educacionais: um estudo sobre o direito à educação e a prevenção da evasão escolar (1988-2022)
Authors: Paulo Walnei Alves de , Oliveira Guilherme Resende de
Published: February 2025

O artigo analisa a importância da educação na prevenção da criminalidade, destacando o direito à educação e as políticas públicas como elementos centrais nesse contexto. A Constituição Federal de 1988 consagra a educação como um direito social, fundamental para a construção de uma sociedade justa, democrática e solidária, onde o acesso ao ensino desempenha papel essencial na formação cidadã e na redução das desigualdades sociais. O texto enfatiza o dever do Estado, da família e da sociedade na garantia desse direito, abordando a necessidade de esforços conjuntos para assegurar sua efetividade e combater problemas estruturais. Além disso, são discutidas as influências de organismos internacionais na formulação de políticas educacionais no Brasil, bem como os desafios enfrentados, como a evasão escolar, a falta de investimentos adequados, a insuficiência de infraestrutura, transporte e espaços apropriados para o aprendizado. Por fim, o artigo destaca a persistência de crianças e adolescentes fora da escola, especialmente em regiões mais vulneráveis, evidenciando a urgência de ações concretas para superar essas barreiras, ampliar o acesso à educação e promover a inclusão educacional de forma equitativa e eficaz.
A subjetividade humana na educação infantil: uma análise possível sobre um levantamento de dados
Authors: Alduino Camila Campos Vizzotto , Argenti Marcia Cristina
Published: February 2025

Refletir sobre o ambiente escolar e os aspectos que circundam este universo se faz por uma tarefa grandiosa e, ao considerarmos os aspectos subjetivos e intrínsecos de cada ser humano ali presente, tais aspectos pluralizam-se em tantos outros. Frente ao nosso cotidiano de trabalho e na certeza de que considerar a constituição da subjetividade humana, se faz necessário as reflexões no início da vida; o objetivo deste trabalho é realizar uma busca nas plataformas de base de dados e analisar as pesquisas publicadas dentro das instituições escolares na etapa de ensino da Educação Infantil/Creche que contemplem a subjetividade dos bebês e das crianças pequenas. Para tanto foi efetivado um levantamento em três distintas bases de dados, tendo como o único recorte o ano de publicação. A sistematização dos dados se deu com a elaboração de quadros e gráficos, com categorias acerca do ano de publicação, o tipo de pesquisa, a área do conhecimento, o método interventivo e o assunto de cada pesquisa. Com isso, pudemos concluir que há uma escassez de publicações que considere a subjetividade humana, na intrínseca relação dos educadores e cuidadores principais nesta inicial etapa de ensino.
O “Desenvolvimento” na Amazônia: processo histórico, político e social
Authors: Dias Walison Almeida , Benjamim Jaisielle Kelem França , Vieira Karine Hamad
Published: February 2025

Este artigo centra-se na reflexão do desenvolvimento Amazônico e como o processo socioeconômico vem moldando a floresta Amazônica e toda a sua biodiversidade como uma região permanente de exploração, suas relações humanas e societárias, evidenciando o problema da violência como decorrente da ação do homem na biodiversidade da floresta. Objetiva-se com esse estudo refletir sobre o processo de desenvolvimento histórico, político e econômico e social da Amazônia. Metodologicamente, este estudo se caracteriza como quanti-qualitativa, que tem como método a interpretação de dados quantitativos e etnográficos por meio do aprofundamento dos resultados das incursões de campo. Trata-se de uma pesquisa que visa ressaltar a importância da manutenção local, regional e global da Amazônia, já que trata-se de um território que contem a mais importante bacia de água doce do mundo, a maior fonte de recursos ictiofaunístico das Américas, de inúmeras agroflorestas, e de um vasto conhecimento etno e biotencnológico de populações tradicionais que representam as riquezas da Amazônia.
Qual o lugar da Imaginação na Filosofia da Química? Implicações para o Ensino de Química
Authors: David Monteiro de Souza Junior  , Vinicius Carvalho da Silva
Published: February 2025

Parte da atividade do químico é lidar com os modelos e representações tanto para explicar fenômenos físico-químicos quanto para guiar a prática experimental em laboratório, seja de pesquisa, ensino ou na indústria. O uso de modelos, como os modelos moleculares por exemplo, ajuda o químico a compreender a distribuição espacial dos átomos em uma molécula, sua geometria e as interações químicas que ela realiza, assim como, suas propriedades físico-químicos, sua acidez e basicidade e as transformações que pode sofrer. Os modelos podem ser classificados como materiais ou abstratos, tendo também propriedades icônicas, analógicas e simbólicas. Os modelos também são instrumentos fundamentais no ensino de química. A questão que este trabalho coloca é, qual é o lugar da imaginação na filosofia da química? E também buscamos refletir sobre suas implicações para a formação do químico. Para responde-la recorreremos a epistemologia do conhecimento pessoal de Michael Polanyi (1891-1976) e a concepção de imaginação como construção metafórica de C. S. Lewis (1898-1963). Concluímos que o espaço onde o químico habita (seja em sala de aula ou no laboratório, de ensino ou pesquisa) é um espaço de criação de modelo, onde ele os manipula, interpreta, avalia e os testa numa dinâmica de construção explicativa. Ou seja, o lócus da imaginação na filosofia da química é a representação imagética que a química faz do mundo, instituindo as bases da construção e articulação de um imaginário químico que orienta as relações simbólicas dentro da comunidade dos químicos, no processo de ensino e aprendizagem em sala de aula e na formação de novos químicos e pesquisadores laboratoriais.
Foot Drop as a complication of critical illness: a retrospective analysis
Authors: Borgers F , Ernon L , Thiessen S , Fivez T , Vander Laenen M , Boer W , Engelen K , De Deyne C , Oosterbos C , Weyns F , Rex S , De Sloovere V , Custer L , Schramme D , Willaert X
Published: February 2025

Background: Foot drop (FD) is commonly encountered in critical care patients, however, the exact pathophysiology and incidence remains unknown.

Design: Retrospective single-center study.

Objectives: We aim to describe the incidence of FD in long lie critically ill patients and propose a protocol to enhance early screening in this population.

Methods: Between 1st of January 2020 and 31 December 2022, we screened all patients with a prolonged ICU stay of seven days or more for the presence of clinical FD, using a Medical Research Council foot dorsiflexion score of less than two. In this group, an ICU physician reviewed medical charts to assess clinical and electrodiagnostic (EDX) signs of peroneal neuropathy.

Outcome measures: We screened for risk factors such as severity of illness, duration of ICU and hospital stay and organ failure.

Results: 57 out of 879 long lie ICU patients had clinical FD, of which 26 had EDX confirmed peroneal neuropathy. Compared to the group without FD, patients with clinical FD had significantly higher APACHE III scores (77.5 versus 72, p < 0.05), ICU length of stay (30 versus 13.6 days, p < 0.05) and hospital length of stay (58.4 days versus 27.3 days, p < 0.05). Furthermore, more patients had received mechanical ventilation (89% versus 62%, p < 0.05) and duration of mechanical ventilation was longer (19 versus 10 days, p < 0.05). Also renal failure (54% versus 22%, p < 0.05), need for renal replacement therapy (33% versus 10%, p < 0.05) and duration of renal replacement therapy (13 days versus 7 days, p < 0.05) was higher in the FD group. Extra-Corporeal Membrane Oxygenation (ECMO) was more prevalent in the FD group (14% versus 2.5%, p < 0.05); duration of ECMO run however was similar in both groups (11.4 days versus 11 days, p = 0.9).

Conclusions: FD is common and associated with a higher degree of organ failure most likely both as cause and effect. Early screening by means of MRC foot dorsiflexion and EDX testing in patients with prolonged ICU stay is essential to avoid delay in treatment and revalidation.
Pharmacokinetics of Acetaminophen in patients with obesity compared to non-obese and overweight patients: a prospective observational cohort study
Authors: De Bock C , De Cock P , De Baerdemaeker L
Published: February 2025

Background: Drug dosing in obese patients can be challenging due to changes in pharmacokinetics. It is unclear which body mass descriptors can be used to describe paracetamol pharmacokinetics in obese patients.

Objectives: we sought to identify which body mass descriptor correlated best to specific pharmacokinetic parameters regarding paracetamol: the volume of distribution (Vd) and drug clearance (Cl). Secondly we aimed to identify the differences in pharmacokinetic parameters in obese and non- obese patients.

Design: we conducted a prospective observational cohort study at Ghent University Hospital.

Methods: 25 obese patients (BMI> 35kg/m²) and 7 non-obese patients (BMI< 30 kg/m²), all undergoing laparoscopic abdominal surgery, received a two-gram loading dose of paracetamol. Blood sampling was performed at set intervals. Pharmacokinetic analysis was performed using PKSolver. Descriptive statistics were performed on both patient groups. Correlation coefficients and simple linear regression were calculated for different body mass descriptors and pharmacokinetic parameters

Results: Non obese patients exhibited significantly higher maximum plasma concentrations of paracetamol. Obese patients exhibited significantly higher Vd and Cl. The order of correlation to Vd in our study was LBM>TBW>IBW. Correlation between drug clearance and TBW was significant. There was a weak positive correlation between LBM and drug clearance, which was not statistically significant. There was a near absent correlation between IBW and drug clearance.

Conclusions: When statistically significant, correlations and predictive values between weight descriptors and pharmacokinetic parameters observed in our study were in general weak to very weak. We might conclude that LBM can be used to calculate loading dose of paracetamol and TBW might be suited for calculation of maintenance doses of paracetamol. . Larger randomised controlled trials with less confounders (e.g. liver surgery) and with assessment of toxic metabolites and hepatotoxicity are needed to improve the clinical relevance of our findings.
PERFORMANCE APPRAISAL: A CRITICAL LOOK AT EMPLOYEE EXPERIENCES – A FIELD RESEARCH
Authors: Moreira Otacilio José , Ramos Américo da Costa , Rodrigues Maria Carolina , Rodriguez Martius Vicente Rodriguez Y
Published: February 2025

Performance appraisal methods are widely considered essential for good organizational management, whether through traditional annual appraisals or through more dynamic, real-time appraisal systems. However, despite substantial progress, there are still significant gaps, such as underestimating the context in which performance appraisal is carried out and a lack of understanding about how organizational culture and social factors affect appraisal decisions. The general objective of this study was to investigate the contribution of employee perceptions to the improvement of the organization's performance evaluation system. The research brings to academia a critical view of performance management practice, assessing how companies may, in some cases, not achieve the intended results. Initially, a narrative literature review was used in order to present current information on the subject and emphasize the gaps in the studies. The study included the participation of 130 employees of companies located in Rio de Janeiro. Based on the responses, it was concluded that organizations need to reconsider the fundamental value of regular employee performance reviews. The results suggest the need to bridge the gap between theory and practice, encouraging greater collaboration between researchers and practitioners to better understand behavior in organizations.
AMBIENTE RESTAURADOR EM JUIZ DE FORA, MINAS GERAIS (MG): DA ANÁLISE TEXTUAL À CONSTRUÇÃO DE UMA AGENDA PROPOSITIVA SOBRE O JARDIM BOTÂNICO DA UFJF
Authors: Yecker Bruna Duque , de Stefano Ercilia , Fontenelle Fabrício Rezende , Barreto João Carlos , da Motta Natália Fernandes , de Miranda Arthur Alves Costa Lignani
Published: February 2025

Esta pesquisa teve como objeto de estudo o Jardim Botânico da Universidade Federal de Juiz de Fora (UFJF). A partir dos conceitos da psicologia ambiental implicando a Teoria da Restauração da Atenção (TRA), o estudo teve como objetivo analisar a percepção dos visitantes que disponibilizaram comentários públicos na plataforma digital Google Avaliações, sendo filtrados com base na técnica de análise de conteúdo (AC) de Bardin (2011). Assim, a pesquisa exploratória e descritiva utilizou suporte da ferramenta Voyant Tools (2025) online para o processamento dos dados visando uma análise textual a partir da nuvem de palavras Cirrus e da análise chamada de Link. Os resultados baseados num corpus textual formado por (n=813) comentários revelaram que o Jardim Botânico da UFJF é amplamente percebido como um espaço que promove contato com a natureza, cumprindo com critérios associados à teoria em tela sobre os ambientes restauradores. Por fim, uma agenda propositiva, que oferece subsídios tanto para planejadores e gestores, quanto para pesquisadores e demais interessados, foi criada com quatro focos principais: (1) Recuperar a atenção; (2) Aliviar o stress; (3) Contribuir para a qualidade de vida; (4) Combater a sazonalidade a partir dos usos do Jardim Botânico da UFJF. Futuros estudos podem a ampliar o desenho metodológico incluindo dados primários aferidos por questionários e entrevistas, o que pode contribuir para se analisar um aspecto importante da TRA o papel das histórias individuais para a interação simbólica que ambientes restauradores podem suscitar.
SISTEMA INTELIGENTE DE SUPERVISÃO E CONTROLE DE CAPACIDADE EM PROCESSOS INDUSTRIAIS: INTEGRAÇÃO DE SCADA, IA E APRENDIZADO DE MÁQUINA
Authors: de Araujo Engº Nelson Michel Matos , Marinelli Filho D. Sc. Nelson , Guimarães D. Sc. Gil Eduardo , Correa D. Sc. Geraldo Nunes , Ferreira Bal. Matheus Rissardi
Published: February 2025

Este estudo propõe um sistema baseado em aprendizado de máquina para supervisão e controle de
capacidade em automação industrial. A solução integra sensores de alta precisão, controladores
lógicos programáveis (PLCs) e um sistema SCADA (Supervisory Control and Data Acquisition),
permitindo o monitoramento e ajuste em tempo real de processos de fabricação. A metodologia
incluiu o desenvolvimento de um software em C# no ambiente Visual Studio 2015, com interface em
um PLC Mitsubishi CPU Q03UDV, e a implementação do sistema em uma linha de produção para
avaliação prática.
Os resultados demonstraram a capacidade do sistema de manter os índices de capacidade do processo
(CpK) acima dos limites críticos (1,33) por meio da correção automática de desvios. Os principais
destaques incluem a integração eficiente com redes industriais e a adaptação dinâmica às
variabilidades de produção. Por outro lado, foram identificadas limitações, como a dependência de
uma infraestrutura robusta e desafios em ambientes com alta interferência eletromagnética.
A discussão destaca o potencial de escalabilidade, a aplicação em outros contextos industriais e a
inclusão de algoritmos avançados, como redes neurais, para aprimorar a capacidade preditiva.
INTEGRAÇÃO DE ROBÔS MÓVEIS AUTÔNOMOS (AMRs) COM LiDAR E CONECTIVIDADE 5G: UM ESTUDO SOBRE APLICAÇÕES EM AMBIENTES HOSPITALARES
Authors: Nunes Eng. Wesley Muller Costa , Marinelli Filho D. Sc. Nelson , Guimarães D. Sc. Gil Eduardo , Alavarce D. Sc. Débora Cristina , Correa D. Sc. Geraldo Nunes
Published: February 2025

A integração de Robôs Móveis Autônomos (AMRs) com tecnologia LiDAR e conectividade 5G
apresenta um potencial transformador para ambientes hospitalares. Este estudo avalia o desempenho
dessas tecnologias em métricas críticas como latência, taxa de transferência, confiabilidade e tempo
de reação, com ênfase em sua aplicação na automação de tarefas logísticas, como o transporte de
materiais médicos. Os resultados indicam que redes 5G superam o WiFi em termos de baixa latência,
alta taxa de transferência e consistência de desempenho, tornando-as ideais para aplicações em tempo
real. Além disso, a tecnologia LiDAR aprimora a navegação dos AMRs, fornecendo mapeamento
tridimensional preciso em ambientes dinâmicos. Apesar dos avanços técnicos promissores, desafios
permanecem, incluindo os custos de infraestrutura, a interoperabilidade e preocupações com
cibersegurança. Os achados destacam a necessidade de abordagens multidisciplinares para superar
essas barreiras e abrir caminho para soluções inovadoras na área da saúde. Esta pesquisa contribui
para o crescente conhecimento sobre as aplicações da Indústria 4.0 no setor de saúde, visando
melhorar a eficiência, a segurança e a qualidade do atendimento ao paciente.
ACCOUNTING PRACTICES AS A STRATEGIC TOOL FOR THE SUSTAINABILITY OF MICROENTERPRISES: A STUDY IN HUMAITÁ/AM
Authors: Góes Ronald Prestes , Moçambite Viviane da S. Costa Novo , Fonseca Marcello Pires , da Cunha Edileuza Lobato , Moreira Giovanna Costa Novo , da Silva Aldenor Moçambite , da Silva Filho Giovani Caldas
Published: February 2025

This study analyzes the importance of accounting practices as a strategic tool for the sustainability of microenterprises in Humaitá, Amazonas. The research seeks to highlight the correlation between the effective implementation of accounting practices and the financial performance of these companies, considering the challenges they face, such as the lack of financial planning and inadequate management. Through a descriptive and qualitative methodology, with a literature review and application of questionnaires to microentrepreneurs in the region, the study aims to identify effective accounting practices, challenges faced and propose solutions to improve accounting management. The results are expected to contribute to local economic development, offering valuable insights for entrepreneurs and public policy makers, in addition to fostering the sustainability of microenterprises in Humaitá.
A LOOK AT FUNCTIONAL LOSSES IN THE ELDERLY POPULATION WITH INTELLECTUAL DISABILITIES
Authors: Monken Sonia Francisca de Paula , Leondarides Maria Regina de Sousa Campos , Tarandach Ester Rosenberg , Giopato Inês Celeste Lourenço , Boschetti Deborah , Decina Rosa Miyasato , Alves Angela Maize Silva , Righini Juliana Barica , Karmeli Daniela , dos Santos Rosângela Aparecida
Published: February 2025

Elderly people with intellectual disabilities face unique challenges and need specialized support to ensure their physical, emotional, and social well-being. Institutions that support elderly people with intellectual disabilities deal with the weakening of family relationships when faced with the aging and exhaustion of parents and/or guardians. In order to understand the reality of adults and elderly people with intellectual disabilities, during the COVID-19 pandemic, in institutions in the city of São Paulo that are active in the Forum for the Aging of Elderly People with Intellectual Disabilities (FEPIDI) in the period 2020-2022, an exploratory research of a qualitative and descriptive nature was developed, covering 198 elderly people with intellectual disabilities. The Forum on Aging for Seniors with Intellectual Disabilities was formed in 2009 with representatives from several institutions in the city of São Paulo that serve people with intellectual disabilities in adulthood and in the aging process. Its objective is to collect data, prepare and disseminate information on the aging of people with intellectual disabilities, and to encourage reflection on public policies and care protocols that can favor the guarantee of rights, autonomy and quality of life for seniors with intellectual disabilities and their families. The study presented by FEDIPI highlights the cognitive vulnerability of an elderly population with intellectual disabilities, especially aggravated by conditions of panic, stress and isolation during the COVID-19 pandemic. The analysis addressed different areas, such as language, memory, reasoning, perception, among others, highlighting the challenges faced by this population.
Relationship of tricipital crease and thigh crease as indicators of fat accumulation in college students
Authors: Robayo Zurita Verónica Alexandra , Culki Paredes Amy Shaiel , Bonilla Carrasco Andrea Michelle , Girón Saltos Katherine , Mosquera Méndez Karen , Zúñiga Sánchez Valeria
Published: February 2025

Assessment of body composition is central to understanding obesity and eating disorders. We aim to determine body fat accumulation by measuring the tricipital and anterior thigh creases to prevent early metabolic risks. This research was carried out through a quantitative cross-sectional study, collecting anthropometric data from 26 students of the Technical University of Ambato, aged between 19 and 22 years, belonging to the third semester of the Nutrition and Dietetics career. The results indicate that the measurement of a single skinfold cannot be an exclusive indicator of body fat percentage. It is necessary to perform an adequate nutritional assessment and take various anthropometric measurements to accurately diagnose the patient's body composition. In conclusion, the exclusive use of tricipital and thigh fold measurements does not provide a complete picture of visceral fat, which is metabolically more active and may be associated with an increased risk of disease.
Evaluation of the Integration of Teaching, Research, and Outreach Processes at UNIANDES
Authors: Alfonso González Iruma , Romero Fernández Ariel José
Published: February 2025

Introduction: The integration of core processes in higher education institutions has been identified as a critical factor for enhancing academic and social impact. The present research focused on evaluating the efficiency in the integration of teaching, research, and community engagement functions at the Universidad Regional Autónoma de Los Andes.Method: A quantitative approach was adopted, and the Analytic Hierarchy Process method was applied to integrate and weight relevant criteria based on the perceptions of administrators, faculty, students, and administrative staff. A structured survey was designed to collect data on the equity of workload distribution, the quality of research, participation in community engagement projects, and satisfaction with resource allocation. The information was processed using specialized software, generating comparison matrices that enabled the identification of priorities and the development of a ranking of improvement alternatives.Conclusions: The results revealed that the distribution of workload exhibited imbalances that favored teaching to the detriment of research and community engagement. It was evidenced that the resources available for research were insufficient and that the integration of community engagement did not reach the desired level. The evaluation by experts established that the reassignment of workload emerged as the most viable strategy, followed by the strengthening of research resources and the restructuring of community engagement programs. It was observed that optimizing the integration of core processes requires structural changes and a reconfiguration of the distribution of responsibilities.
Investment approach of higher education institutions to the development of educational platforms
Authors: Bobro Natalia , Ivanova Dora , Pyvovarov Kostyantyn , Shatskaya Zorina , Kucheriavyi Volodymyr
Published: February 2025

Introduction: Investment in education is a determining factor in improving its quality, especially investment in innovative tools such as modern educational platforms. Objectives: The aim is to characterise the critical determinants of the investment approach of higher education institutions to develop educational platforms. Methods: The paper uses correlation and regression analysis, as well as analysis of secondary survey data. Results: As a result of the study, the main determinants of the investment approach of HEIs to the development of educational platforms were characterised. These are the motivation for investment, student expectations, and the model and sources of investment. It was found that the efficiency, accessibility of education, and productivity of human capital are positively correlated with education expenditures, innovation, and the level of adaptation to online education. At the same time, the most substantial impact was observed from the adaptation of online education on the indicator of the human capital index (the HCI).  Conclusions: It was concluded that the efficiency, accessibility of education and productivity of human capital are the key goals and motivations for investment in education. Through the analysis of survey data, the critical expectations of students from learning on online platforms were identified. An international experience analysis has helped identify the most popular investment models.
Next-Generation Educational Technologies in University Settings
Authors: Barbashova Iryna , Hetmanenko Liudmyla , Kukhniuk Oksana , Vasylenko Iryna , Snisar Olena
Published: February 2025

Introduction: In view of digitalisation, use of modern technology in education has become necessary as education is aiming at quality. For teachers and facilitator, the impact of technology namely e-learning, blended learning, mobile learning and AI on learners and the learning outcomes has to be explored.
Methods: Systematic analysis, comparative analysis, modelling, and classification of educational technologies were used in the study. The purpose of these methods was to discover main features of modern educational technologies and to appraise their role in the teaching and learning processes in higher education.
Results: Results suggest that modern learning technologies help make education much better and student performance significantly improves with the integration of modern learning technologies. Blended learning and AI application leverage flexible, personalized learning, which is offered in multiple modes of delivery, texts, videos, audio, and more. Technological aspects are shown to be essential for promoting such competences in students.
Conclusions: New technologies like AI and cloud based apps give you the ability to transform your course design with personalisation, collaboration, and direct communication between teachers and students. These improvements serve to highlight that well defined guidelines need to be combined with practical tools to optimise the integration of modern technologies into educational processes to promote the professional growth and activity of students.
Trivial content on social media from the point of view of a number of young people in Arab countries
Authors: Al-Timimi Fawzi Mohammed Ridha
Published: February 2025

The current research aimed to identify trivial content on social media from the point of view of a number of young people and the degree of spread of trivial content on social media in a number of Arab countries, as well as the differences in the spread of trivial content according to the different variables (gender, specialization, country). Accordingly, the researcher built a scale for trivial content on social media, consisting of (25) statements, the psychometric properties of which were verified for validity and reliability, and were applied to a sample of (1500) young people in a number of Arab countries (Iraq, Syria, Egypt, Saudi Arabia). After analyzing the results, the study concluded that there are statistically significant differences in the perception of the research sample members of the spread of trivial content on social media according to the difference in the gender variable in favor of females, in favor of theoretical specializations, and in favor of Saudi Arabia. Trivial content is widespread in Saudi Arabia, as Saudi Arabia is one of the countries from which many trivial contents originate and spread across countries, and that content makers on social media are exploited by companies specialized in marketing and promoting some ideas, meaning that it has become a means Easy and cheap to achieve certain goals, and many recommendations and suggestions were made.