bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrated plasma and exosome long noncoding RNA profiling is promising for diagnosing non-small cell lung cancer
Authors: Wang Na , Yao Cong , Luo Changliang , Liu Shaoping , Wu Long , Hu Weidong , Zhang Qian , Rong Yuan , Yuan Chunhui , Wang Fubing
Published: June 2023

Objectives

Non-small cell lung cancer (NSCLC) accounts for more than 80 % of all lung cancers, and its 5-year survival rate can be greatly improved by early diagnosis. However, early diagnosis remains elusive because of the lack of effective biomarkers. In this study, we aimed to develop an effective diagnostic model for NSCLC based on a combination of circulating biomarkers.

Methods

Tissue-deregulated long noncoding RNAs (lncRNAs) in NSCLC were identified in datasets retrieved from the Gene Expression Omnibus (GEO, n=727) and The Cancer Genome Atlas (TCGA, n=1,135) databases, and their differential expression was verified in paired local plasma and exosome samples from NSCLC patients. Subsequently, LASSO regression was used to screen for biomarkers in a large clinical population, and a logistic regression model was used to establish a multi-marker diagnostic model. The area under the receiver operating characteristic (ROC) curve (AUC), calibration plots, decision curve analysis (DCA), clinical impact curves, and integrated discrimination improvement (IDI) were used to evaluate the efficiency of the diagnostic model.

Results

Three lncRNAs-PGM5-AS1, SFTA1P, and CTA-384D8.35 were consistently expressed in online tissue datasets, plasma, and exosomes from local patients. LASSO regression identified nine variables (Plasma CTA-384D8.35, Plasma PGM5-AS1, Exosome CTA-384D8.35, Exosome PGM5-AS1, Exosome SFTA1P, Log10CEA, Log10CA125, SCC, and NSE) in clinical samples that were eventually included in the multi-marker diagnostic model. Logistic regression analysis revealed that Plasma CTA-384D8.35, exosome SFTA1P, Log10CEA, Exosome CTA-384D8.35, SCC, and NSE were independent risk factors for NSCLC (p<0.01), and their results were visualized using a nomogram to obtain personalized prediction outcomes. The constructed diagnostic model demonstrated good NSCLC prediction ability in both the training and validation sets (AUC=0.97).

Conclusions

In summary, the constructed circulating lncRNA-based diagnostic model has good NSCLC prediction ability in clinical samples and provides a potential diagnostic tool for NSCLC.
Low-temperature self-healing polyurethane adhesives via dual synergetic crosslinking strategy
Authors: Zhang Yu , Zheng Jian , Zhang Xiao , Liu Yahao
Published: June 2023

Damage to polymer adhesives is one of the most common reasons for structural integrity damage of composite solid propellants. The introduction of self-repairing technology into the adhesive is expected to solve this problem. However, at low temperatures, the self-repairing and mechanical properties of the materials are greatly impaired, thereby limiting the application of self-repairing adhesives in composite solid propellants. In this study, based on the dual synergistic crosslinking strategy, a polyurethane adhesive exhibiting excellent self-healing and mechanical properties at low temperatures was successfully prepared. The adhesive exhibited high self-repairing efficiency and ultra-long elongation at break at low temperatures. Specifically, at a low temperature of −40°C, the self-repair efficiency was over 70% and the elongation at break was over 1,400%, which were much higher than the results of the control group. Moreover, the strength was comparable to that of the control group. This polyurethane adhesive shows excellent self-healing and mechanical properties at low temperatures and is expected to provide the strong self-healing ability and mechanical properties for composite solid propellants, alleviating the problem of structural integrity damage.
Emergence of energy optimization in MIMO-OFDM communication system with hybrid teamwork-grasshopper optimization
Authors: Gopadi Harish Kumar , Rao Polipalli Trinatha
Published: June 2023

In the application of mobile multimedia and wireless communication system needs an enormous amount of data. Due to the usage of a huge data rate, a superior amount of energy is offered to BER, which effectively enhances the entire energy consumption rate in the system, and also, the generation of CO2 emission leads to global warming. Hence, professionals searched for energy-efficient approaches for attaining enhanced data rates in wireless communication systems. Then, professionals observed the energy efficacy as well as QoS as an essential factor in developing and validating the mobile multimedia communication system that has created superior interest in recent days. In this paper, energy-efficient models are suggested for MIMO-OFDM mobile multimedia communication systems with statistical QoS constraints. Hence, this research suggests a new MTGSO for energy optimization in the MIMO-OFDM mobile multimedia communication system to improve spectral efficiency and system capacity. Thus, the empirical result of the designed method attains better performance regarding average power constraints, achieving 29.8 %, 21.3 %, 123.8 %, and 4.2 % enhanced than SSO, FOA, GSO, and TOA. This energy-efficient hybrid algorithm for MIMO-OFDM proves its efficiency in terms of various performance measures and statistical measures.
Bagley v. Mt. Bachelor, Inc.: A New Direction for the Enforceability of Sports Waivers?
Authors: Yen Alfred C.
Published: June 2023

In Bagley v. Mt. Bachelor, Inc., the Oregon Supreme Court considered a topic of widespread, daily significance – the enforceability of tort waivers in the context of sports and recreation. Although these Sports Waivers vary considerably in their precise form and deployment, they function primarily to release organizers and providers of sports and recreation from claims of negligence. Almost every adult has signed such a waiver. Indeed, such waivers are so common that one might fairly think that (assuming the waivers are enforceable) the typical sports or recreation provider faces little to no accountability for its own negligence. Bagley stands out among recent cases because it opened new directions for how to evaluate and draft Sports Waivers.
China’s Approach to Sustainable Development in Free Trade Agreements
Authors: Wei Dan , Rafael Ângelo Patrício
Published: June 2023

The question of how to adequately integrate environment and labor provisions in free trade agreements is still a difficult one for both States and academicians. This article explores China’s approach to environment and labor issues in free trade agreements. For reference and comparison, it relies on the European Union’s and the United States’ approaches in their respective FTAs. The article identifies China’s preference for a case-by-case approach to the inclusion of environmental chapters in its FTAs. Additionally, in most FTAs it avoids to include provisions on labor standards. These two preferences represent major divergences from the European Union’s and the United States’ approaches, characterized by inclusion of chapters on environment and labor in all their modern FTAs. The article also finds that China’s FTAs rely solely on consultations and cooperation for the implementation of environmental and labor provisions, within the framework of Joint Committees and avoid the inclusion of civil society mechanisms. Moreover, resolution of disputes relies exclusively on consultations, in a diverse procedure than the one applicable to trade disputes. Despite alignment with the European Union model, this is another major point of divergence with the United States’ model, which applies the same enforcement mechanism for both environment and labor issues and trade issues and includes the possibility of applying sanctions. Finally, the article concludes that China’s options with regards to the treatment of environment and labor concerns in its free trade agreements aligns with both its domestic governance approach and its approach to international cooperation.
Qualitätsentwicklung in der Erwachsenenbildung im Zeichen der Ökonomisierung
Authors: Nittel Dieter , Kılınç Marlena , Klusemann Stefan
Published: June 2023

Der Aufsatz diskutiert den Zusammenhang zwischen dem sozialen Phänomen der Ökonomisierung und Erfahrungen im Umgang mit der Qualitätsentwicklung im Handlungsfeld der Erwachsenenbildung. Den Kern des Beitrags bildet eine Fallstudie über zwei stark kontrastierende Weiterbildungsorganisationen in Deutschland auf der Basis zweier Expert*inneninterviews. Bei der Ökonomisierung handelt es sich um einen Gegenstandsbereich, der keineswegs klar definiert ist – dem viele Sozial- und Erziehungswissenschaftler*innen aber Eindeutigkeit unterstellen. Die Fallbeispiele zeigen, dass Prozesse der Ökonomisierung auf einen nicht-ökonomischen Bewegungsmechanismus angewiesen sind.
Eco-friendly extraction of cellulose from Ailanthus altissima for nanocellulose production: physico-chemical properties
Authors: Rehman Noor , Hussain Zahid , Ullah Hidayat , Khan Muhammad Naveed , Khan Abbas , Khan Nasir Mehmood , Mian Inam Ullah
Published: June 2023

Nanocellulose is a promising bionanomaterial which has gained significant attention due to its diverse applications in many important areas. Thus, scientists and technologists are constantly searching for the most economical, sustainable, and eco-friendly production to fulfill its growing need. In this study, cellulose and nanocellulose were isolated from the plant of Ailanthus altissima utilizing a multi-step, environmentally friendly approach involving alkaline treatment and chlorine-free bleaching. The analysis of purified cellulose was conducted by utilizing modern techniques, such as X-ray Diffraction (XRD), thermogravimetric analysis (TGA) and scanning electron microscopy (SEM). XRD analysis determined the degree of crystallinity of extracted cellulose i.e. 67.41 % and crystallite size 43.4 Å by using Segal method and Scherrer equation respectively. The TGA curve showed the thermal degradation pattern of the cellulosic and nanocellulosic material. Furthermore, SEM technique was used to study the morphological changes in the surface of lignocellulosic fibers with chemical treatment. This novel biomass source has to be a potential usage for a wide range of applications in industrial processes.
Are Metabolic Power Distribution and Accelerometer-Based Global Positioning System Variables Associated With Odds Ratios of Noncontact Injuries in Professional Soccer Players?
Authors: Nobari Hadi , Alves Ana Ruivo , Abbasi Hamed , Khezri Davood , Zamorano Angel Denche , Bowman Thomas G.
Published: June 2023

Nobari, H, Alves, AR, Abbasi, H, Khezri, D, Zamorano, AD, and Bowman, TG. Are metabolic power distribution and accelerometer-based GPS variables associated with odds ratios of noncontact injuries in professional soccer players? J Strength Cond Res XX(X): 000–000, 2022—The present study was intended to i) investigate the relationship between metabolic power average (MPA), acceleration (AcZ) and deceleration (DcZ) zones, and their differences (Δ) on 3 load levels with noncontact injuries in professional players throughout a full soccer season and ii) to analyze the injury risk associated between high-load versus low-load levels for each of the aforementioned parameters with odds ratios (OR) and relative risk (RR), respectively. Twenty-one professional soccer players (age = 28.3 ± 3.9 years) were monitored during a full season (48 weeks) through global positioning system (GPS). A relationship between MPA and accelerometer-based GPS, mainly in explosive actions (i.e., AcZs and DcZs), was found. A higher incidence of injuries in the high-load weeks compared with the low-load weeks were reported (mainly in MPA, AcZ1, AcZ2, and DcZ3 variables). Moreover, significant means of OR (mean = 4.3) and RR (mean = 2.6) of noncontact injuries were established in intense periods with higher metabolic load (i.e., power accelerations, AcZ1, x
2 = 0.022). Our results may be useful for coaches, sports scientists, and researchers regarding the optimization of the athletes' performance, as well as providing insights about the impact of intense exercise.
Los Estudios Sociales, la cultura política y la ciudadanía: Entrevista al profesor Carlos Bolaños Chaves
Authors: Mathiew Morales Luis
Published: June 2023

Interview with Carlos Bolaños, teacher of Social Studies in high school and at the School of History, Universidad Nacional, in which he addresses the issue of pedagogy related to culture and the formation of critical citizenship that responds to the demands of today's society. The paper is a tribute to the work and contributions of Professor Bolaños to Social Studies as a school subject and as a field of research.
El problema epistemológico de la causalidad histórica en la didáctica de la historia: el papel de las causas en las explicaciones de ocho docentes de Estudios Sociales
Authors: Meléndez Montero Arturo
Published: June 2023

The objective of this article is to know how the epistemological problem of historical causality manifests itself in the teaching of history focusing especially on the historical explanations developed by teachers.  For this, first a theoretical-epistemological discussion is presented regarding the causes and their functioning in the historical explanation recognizing that the systemic approach supposes an overcoming of the reductionisms related to the nomological and intentional types of explanation.  Secondly, an empirical study carried out through a qualitative survey applied to eight Social Studies teachers is exposed.  It is concluded that most of these educators do not understand the complex nature of historical causality which is why they base their explanations on epistemological reductionisms.
Representaciones sociales, subjetividades y territorio: La metamorfosis durante la formación inicial docente de estudiantes de I y IV nivel, en la Carrera de Enseñanza de Estudios Sociales y Educación Cívica
Authors: Meza Bolaños Ruth , Moya Fernández Yasmine , Cordero Benavides Josué , Calderón Hernández Axel
Published: June 2023

The objective of this article is to describe the influence of Social Representations on the territory, personal experiences and geographical thought in the initial teacher training of students of I and IV level of the career in Teaching of Social Studies and Civic Education of the National University of Costa Rica. It was based on the approaches on the Social Representations of the Classical School to understand how they are built and what elements intervene. The methodology used was based on the qualitative paradigm and the phenomenological-constructivist approach that allowed analyzing the subjectivities of the study subjects in the process of knowledge construction. It was concluded on the need to transform the teaching of geography in the career, implementing practical methodologies that approach the materiality of geographical thought. Likewise, the implementation of the territory was raised as an integrating axis in Social Studies.
Resignificar la interculturalidad en el sistema educativo costarricense
Authors: Salazar Chavarría Kenett
Published: June 2023

Taking critical-decolonial thinking as a reference, a theoretical review is made of the curricular policies in Intercultural Education developed in Costa Rica during the last decades; with the objective of problematizing the methods selected for their design and execution, while opening a theoretical debate from the teachers' collective around the hegemonic character of the contents that the Official Curriculum intends to transmit. In line with the proposed objectives, this theoretical essay is based on the technique of content analysis, to demonstrate that the curricular reforms in interculturality are framed within the neoliberal globalization project, whose purpose is the reproduction of historical domination logics, in this case through the official educational systems, under the guise of discourses such as tolerance and inclusion. In view of these scenarios, emphasis is placed on the need to vindicate the role of teachers in the construction of collective proposals that respond to the diversities present in the country's educational communities.
Reflexión crítica responsable para una formación ciudadana en tiempos de conquistas
Authors: González Rivero Berta Margarita
Published: June 2023

Development of technology and science has brought about dizzying changes; however, they do not always put themselves at service of humanity. Today it is much more dangerous what technologies can do in unscrupulous hands. A theme has emerged that has the purpose of exposing the effects of the semiotic bombardment that humankind receives. Several texts appear on the manipulation of emotions. The article aims to delve into this topic and provide a vision that contributes to alert people on the consequences of manipulation. The methodology used is qualitative, with inductive-deductive, synthetic-analytical methods based on the cultural-historical approach. As descriptors that serve as a common thread of the study process are selected: processes that impact the human being, citizen education and responsible critical reflection. The results provide a framework where the descriptors are related and it is concluded that to counteract the situation it is not enough to prevent its influence, but rather it requires the development of the personality.
USO DA TERMOGRAFIA E ULTRASSONOGRAFIA POWER DOPPLER PARA AVALIAÇÃO DA RESPOSTA TECIDUAL EM FALHAS ÓSSEAS PREENCHIDAS COM BIOMATERIAL EM OVINOS
Authors: SILVA D. C. B. , PARETSIS N. F. , MARCONDES G. M. , ZOPPA A. L. V.
Published: June 2023

Biomateriais tem diversas indicações como auxiliares no processo de reparação óssea, além de terem função de substituto ósseo em perdas extensas. Diversas são as vantagens de sua utilização, como por exemplo, auxílio na osteocondutividade, estímulo de neovascularização, potencial antimicrobiano, entre outros. Falhas ósseas foram realizadas nas tíbias de seis ovinos da raça Santa Inês e preenchidas com biomaterial à base de quitosana, colágeno e hidroxiapatita. Um membro foi considerado controle e outro membro tratado segundo estudo randomizado. Foram realizadas avaliações termográficas e por ultrassonografia Power Doppler em todos os animais do estudo, semanalmente, nos dias D0, D7, D14, D21, D28, D35, D42 e D56. Não houve diferenças significativas com relação à temperatura mínima, máxima e média entre os grupos com biomaterial e controle nas imagens termográficas. Houveram variações com relação ao tempo dentro de ambos os grupos. Com relação à presença de vasos na ultrassonografia Power Doppler não houve diferenças estatísticas entre os grupos, exceto no dia 21 (P=0,031). Dentro das possibilidades de avaliação que os exames de imagem fornecem, a termografia e a ultrassonografia Power Doppler mostraram-se ferramentas não invasivas de avaliação pós-operatória de processo inflamatório e neovascularização, sendo realizadas semanalmente, permitindo acompanhamento fidedigno e detalhado ao longo do experimento, sem gerar desconforto ou estresse aos animais. Não houve indícios de complicações relacionadas ao biomaterial.
Parenthetical Units and Structures in Italian and German spoken language: Prosodic and textual analysis
Authors: Saccone Valentina , Trombetta Chiara
Published: June 2023

This work presents the prosodic analysis of Parenthetical Units in spoken Italian and German within the theoretical framework of the Language into Act Theory (L-AcT), which defines such textual units as Parentheses (PARs), i.e. devices used by the speaker to add information to the utterance on a secondary level of the text. Data were extracted from the Italian Minicorpus of the DB-IPIC resource and from the German FOLK corpus. Linguistic content and distribution of Parentheses were analyzed. Furthermore, a subset of approximately 100 PARs was selected for each corpus and these were prosodically analyzed in relation to the mandatory textual units called Comment within the L-AcT framework, which express the illocutionary force of the utterance. The results show similar characteristics for the two languages, such as an overall decrease of f0 values of the PARs and the correlation between the length of the PARs, as well as the presence of additional units separating it from the COM, and frequency values. The authors also noted the presence of Parenthetical Structures that go beyond the level of the simple textual unit, which could suggest that Parentheses are a wider textual strategy operating as inter-utterance.
Répétitions et variations des textes générés
Authors: De Cesare Anna-Maria
Published: June 2023

Texts automatically generated in French by commercial software have not been the subject of in-depth linguistic analyses until now, even though they are becoming increasingly common, especially in the media. The questions we are interested in concern their 'quality', in particular their repetitiveness and specificity compared to non-generated texts. The paper is organized as follows: After defining the theoretical concepts able to describe the specificities of generated texts and presenting our work corpus (composed of 100 articles produced by the CAC40 software in the field of finance), we show that the similarity of generated texts does not only concern the lexicon, but can also be traced in less obvious properties, such as their macro- and micro-structuring and their information structural properties. Our conclusion is that the high repetitiveness of texts generated by the CAC40 software is not in itself a problem because it becomes obvious only when many texts are compared. Taken individually, each generated text shows a sufficiently rich internal variation to be natural.
Optimization of physical and nutritional factors for synthesis of lignin degrading enzymes by a novel strain of Trametes vericolor
Authors: Iqbal Hafiz Muhammad Nasir , Asgher Muhammad , Bhatti Haq Nawaz
Published: June 2023

This paper reports the production of ligninase enzymes by a new strain of Trametes versicolor IBL-04 producing a novel pattern of ligninolytic enzymes with highest MnP activities followed by LiP and laccase. In previous studies Trametes versicolor has been reported to produce higher activities of MnP, followed by laccase and LiP. Lignocellulosic substrates including wheat straw, rice straw, banana stalks, corncobs, corn stover, and sugarcane bagasse were used in solid state fermentation (SSF) for the production of ligninases including peroxidase (LiP), manganese peroxidase (MnP), and laccase by Trametes versicolor IBL-04. Maximum production of MnP (998 U/mL), LiP (620 U/mL), and Laccase (49.7 U/mL) was observed after 5 days in the SSF medium containing 5g rice straw (60% w/w moisture) in still culture SSF. Moisture, pH, temperature, inoculums size, additional carbon and nitrogen sources, and surfactants had a significant influence on ligninase synthesis by the fungus. Production of ligninases was substantially enhanced by optimizing SSF production process. Maximum MnP (1775 U/mL), LiP (1663 U/mL), and laccase (99 U/mL) were produced when rice straw (5g) at 66.6 % moisture (w/w) receiving 5ml inoculum was incubated at pH 4.0 and 30oC in the presence of maltose (1% w/w) as carbon source, urea (0.2% w/w) as nitrogen source and 1mM Tween-80 (0.3 ml) as surfactant.
Investigating changes in the chemical consitutents and dimensional stability of heat-treated hornbeam and uludag fir wood
Authors: Aydemir Deniz , Gunduz Gokhan , Altuntaş Ertuğrul , Ertas Murat , Şahin H. Turgut , Alma M. Hakkı
Published: June 2023

Changes in chemical constituents and some physical properties such as swelling and water absorption of hornbeam (Carpinus betulus L) and uludag fir (Abies bornmulleriana Mattf.) wood were investigated after heat treatment at three different temperatures (170 oC, 190 oC, and 210 oC) for three different durations (4, 8, and 12 hours) by using thermal gravimetric analysis (TGA) and Fourier transform infrared (FTIR) spectrometry. The results of TGA show that there was less weight loss in the main degradation region (300-500 oC) for the heat-treated samples as compared to untreated (control) samples. In addition, there was greater weight loss of hornbeam wood than of uludag fir wood in a similar degradation region. This difference could be due to the chemical constituents of softwoods and hardwoods. The results of FTIR spectrometry show that the chemical constituents of the hornbeam wood samples were more affected by heat treatment. All heat-treated samples exhibited lower water absorption and swelling compared to control samples. It was found that the relative decrease in swelling and water absorption for uludag fir was higher than for hornbeam. The maximum decrease in water absorption and swelling was found for both species that were heat-treated at 210 oC for 12 hours.
Nontrivial solutions for an asymptotically linear Delta alpha-Laplace equation
Authors: Xu Jiafa , Chen Jia , O'Regan Donal
Published: June 2023

In this paper, we study a class of degenerate unperturbed problems. We first investigate some properties of eigenvalues and eigenfunctions for the strongly degenerate elliptic operator and then obtain two existence theorems of nontrivial solutions when the nonlinearity is a function with an asymptotically condition.
Dynamic analysis and optimal control of a novel fractional-order 2I2SR rumor spreading model
Authors: Ye Maolin , Li Jiarong , Jiang Haijun
Published: June 2023

In this paper, a novel fractional-order 2I2SR rumor spreading model is investigated. Firstly, the boundedness and uniqueness of solutions are proved. Then the next-generation matrix method is used to calculate the threshold. Furthermore, the stability of rumor-free/spreading equilibrium is discussed based on fractional-order Routh–Hurwitz stability criterion, Lyapunov function method, and invariance principle. Next, the necessary conditions for fractional optimal control are obtained. Finally, some numerical simulations are given to verify the results.
The effectiveness of the physical therapy program for patients with metabolic syndrome based on the study of the dynamics of the functional state of the autonomic nervous system and hemodynamic parameters
Authors: Kalmykova Yuliya , Kalmykov Sergey
Published: June 2023

Purpose: determination of the influence of the physical therapy program on the dynamics of blood pressure, heart rate and vegetative Kerdo index in patients with metabolic syndrome.

Material & Methods: the study was conducted on the basis of the Municipal institution of health care "Kharkiv City Hospital No. 3". 28 young women were under observation, randomly divided into two groups: the main group (MG) – 14 patients and the control group (CG) – 14 patients. The mean age of patients in the MG was 31,49±0,71 years, in the CG – 31,06±0,57 years. The patients of the main group underwent rehabilitation measures according to the author's program of physical therapy, which included a hypocaloric diet with a lipid-lowering orientation (lipid-lowering diet No. 1), the basic principles of which are developed by the American Heart Association, therapeutic massage for patients with alimentary-constitutional obesity; kinesitherapy using elements of sports-oriented aerobics and special physical exercises based on Pilates gymnastics using fitballs and expanders; dosed walking in combination with breathing exercises, taking into account the activity of the autonomic nervous system, for patients in the control group – according to the program used for metabolic syndrome in the indicated medical institution. To identify the effectiveness of the author's program, a comparison was made of heart rate, arterial tonometry, vegetative Kerdo index (V.I.) at the beginning and end of the study.

Results: in the determination and analysis of blood pressure, heart rate and vegetative Kerdo index during the second study, we noted the normalization of heart rate, SBP, DBP in women of the main group (р>0,05), in the control group, the dynamics of DBP was statistically insignificant (р>0,05). In women of the main group, the heart rate during the second examination compared with the primary one decreased by 19,8%, the SBP level decreased by 9,1%, the DBP level decreased by 11,0%. In CG patients, the heart rate during the second study decreased by 8.8% compared to the primary one, the SBP level decreased by 5,2%, the DBP level decreased by 3,9% (р>0,05).

Conclusions: comparison of the obtained results of the study showed the normalization of hemodynamic parameters and the tone of the autonomic nervous system, there was also a tendency towards balance of the sympathetic and parasympathetic divisions of the ANS in patients of the main group, in the physical rehabilitation of which therapeutic exercises were applied with the use of regulated breathing exercises, taking into account the tone of the sympathetic or parasympathetic divisions of the autonomic nervous system, which helps to improve the quality of life of patients with metabolic syndrome.
COVID-Inconfidentes - SARS-CoV-2 seroprevalence in two Brazilian urban areas in the fourth quarter 2020: study protocol and initial results
Authors: Lúcia Meireles Adriana , Garcia Lourenção Luciano , Alves de Menezes-Júnior Luiz Antônio , Nascimento Coletro Hillary , Sousa Justiniano Irene Carolina , Silva de Moura Samara , Popolino Diniz Amanda , Da Silva Sabião Thaís , Sampaio Rocha Ana Maria , Priscila Batista Aline , Nunes Lage Nara , Dos Santos Simões Bárbara , Ali Santos Carolina , De Deus Mendonça Raquel , De Souza Andrade Amanda Cristina , Furbino Barbosa Keila , Zumerle Masioli Cássio , Cardoso Carraro Júlia Cristina , Carvalho de Menezes Mariana , Rezende Macedo Nascimento Renata Cristina , Roever Leonardo , Teixeira Caiaffa Waleska , Lins Machado Coelho George Luiz
Published: June 2023

Objective: To describe study protocol and initial results of research project COVID-Inconfidentes. Method: This paper described the methodological procedures adopted and the prevalence of the SARS-CoV-2 infection in the population. A household survey was conducted between October and December 2020, in two historic cities of Brazil's mining region. Anti-SARS-CoV-2 antibody was detected using the Wondfo® rapid test. The face-to-face interview consisted of administration of a questionnaire containing registration data, sociodemographic and economic variables, living habits, general health condition, mental health, sleep habits, and eating and nutrition. Results: We evaluated 1,762 residents, of which 764 (43.4 %) were in Mariana and 998 (56.6 %) in Ouro Preto. For both cities, 51.9 % of the interviewees were female, with a predominance of the age range 35 to 59 years old (47.2 %). The prevalence of the SARS-CoV-2 infection was 5.5 % in both cities, 6.2 % in Ouro Preto, and 4.7 % in Mariana (p-value > 0.05). Conclusion: The study was effective to estimate the seroprevalence of infection by the virus and its findings will enable further analyses of the health conditions of the population related to social isolation and the risk of infection with SARS-CoV-2.
Phase transformation, thermal behavior, and magnetic study of new (FeSiBP)100-XCuX glassy alloys obtained by melt-spinning in air
Authors: Perea-Cabarcas D. , Parra Vargas C. A. , Echeverría Echeverría F. , Bolívar Osorio F. J.
Published: June 2023

In the current work, a new variation of the FeSiBPCu system with good glass forming ability and soft magnetic properties was developed and investigated. The effect of copper addition on the FeSiBP base alloy was studied in the system (Fe0.77Si0.08B0.1P0.05)100-xCux with x = 0, 0.25, 0.5, 0.75 and 1.0 at%. Microstructural evolution upon the annealing process was evaluated by XRD and TEM, revealing the formation of α-Fe(Si), Fe2B and Fe3(B,P) crystalline phases. VSM allowed to determine that the combination of chemical composition and microstructure with the best soft magnetic properties after the annealing corresponds with the alloy with 0.75% Cu. In addition, activation energy for glass transition and the first crystallization event were calculated using the Kissinger method. The research findings demonstrated that maintaining the relationship between the main elements, it is possible to keep the good glass forming ability with the possibility of developing a nanocrystalline structure with soft magnetic performance.

Graphical abstract
On the creation of near-surface nitrogen-vacancy centre ensembles by implantation of type Ib diamond
Authors: Healey A. J. , Scholten S. C. , Nadarajah A. , Singh Priya , Dontschuk N. , Hollenberg L. C. L. , Simpson D. A. , Tetienne J.-P.
Published: June 2023

Dense, near-surface (within $$\sim 10$$

∼
10

 nm) ensembles of nitrogen-vacancy (NV) centres in diamond are moving into prominence as the workhorse of many envisaged applications, from the imaging of fast-fluctuating magnetic signals to enacting nuclear hyperpolarisation. Unlike their bulk counterparts, near-surface ensembles suffer from charge stability issues and reduced formation efficiency due to proximity to the diamond surface. Here we examine the prospects for creating such ensembles by implanting nitrogen-rich type Ib diamond, aiming to exploit the high bulk nitrogen density to combat surface-induced band bending. This approach has previously been successful at creating deeper ensembles, however we find that in the near-surface regime there are fewer benefits over nitrogen implantation into pure diamond substrates. Our results suggest that control over diamond surface termination during annealing is key to successfully creating high-yield near-surface NV ensembles generally and implantation into type Ib diamond may be worth revisiting once that has been accomplished.

Graphical Abstract
The Development Teacher Role and Counseling at Madrasah Ibtidaiyyah
Authors: Elihami Elihami , Melbourne Mohd.
Published: June 2023

The purpose of this study is to investigate a new approach to develop teachersâ€™ soft skills and provide counseling guidance for students at Madrasah Ibtidaiyah Darud Da'wah wal Irsyad (MI DDI). The research employed a qualitative case study using a bibliographic design with systematic and explicit mapping methods. Data was collected through semi-structured interviews to examine the learning method. The findings show that the innovation role of an Islamic religious education teacher includes counseling activities for students. The collaborative implementation in terms of role between the religious teacher and counselor roles is essential for the successful development of this approach. This research contributes to the development of a new learning method for soft skills and counseling guidance for elementary school students. It demonstrates an effective and efficient strategy to teach and improve teachersâ€™ soft skills by integrating soft skill training into courses focused on hard skills.Â
Studentsâ€™ Understanding of Nature of Science in Islamic Private School
Authors: Safkolam Roswanna , Nuangchalerm Prasart , Zaky El Islami R. Ahmad , Saleah Phurkhonni
Published: June 2023

The objective of this study is to explore Muslim studentsâ€™ level of understanding regarding the nature of science (NoS) and compare their understanding between genders in private Islamic schools in Thailand. Descriptive statistics and t-test independent was used to analyze the data. The results revealed that a majority of the participants held a transitional perspective on NoS. Furthermore, there were no statistically significant differences in NoS comprehension between genders at the .05 level. To enhance students' understanding of NoS in all domains, it is recommended that learning activities in private Islamic schools promote a reflective attitude towards NoS.
Professional Development for Islamic Religious Education and Madrasah Teacher
Authors: Mulyana Rohmat , Kurahman Opik Taupik , Fauzi Reza
Published: June 2023

In Indonesia, PPG (Pendidikan Profesi Guru/Teacher Professional Development) program is designed for in-service teachers to develop their competence and professionalism to meet national education standards. This program requires participating teachers to take UKMPPG (Uji Kompetensi Mahasiswa Pendidikan Profesi Guru/Competence Test for Teacher Professional Development) which covers both UP (Uji Pengetahuan/Knowledge Test) and UKIN (Uji Kinerja/ Performance Test). This study aims to examine teachersâ€™ performance in UKIN test held by LPTK (Lembaga Pendidik dan Tenaga Kependidikan/Teacherand Academic Staff College) UIN Sunan Gunung Djati. Data was collected using observation and documentation techniques. Data analysis was done using a qualitative descriptive method. The results showed that LPTK UIN Sunan Gunung Djati has provided good facilities to support the implementation of the PPG program. There are eight types of subjects tested in UKIN. There are differences in scores between classes in the UKIN test which shows variations in scores for each class with a total of 11 class intervals. The passing score for the UKIN test in 2021-2022 is 99.56%. The results of this research are expected to contribute to policy making related to the implementation of PPG in the Ministry of Religious Affairs in Indonesia.
The Development of Reflective Practices for Islamic Religious Education Teachers
Authors: Purwanto Yedi , Saepudin Aep , Sofaussamawati Sofaussamawati
Published: June 2023

Continuous professional development for teachers is crucial in order to enhance their competence and professionalism. It is equally important for student teacher candidates to engage in field practice activities that promote self-reflection. The main objective of this research is to investigate how self-reflection among prospective Islamic Religious Education teachers contributes to the development of their professionalism. The study involved six participants from two universities, namely Unisba (Universitas Islam Bandung) and UPI (Universitas Pendidikan Indonesia). Qualitative methods were employed, utilizing case studies based on Stake's approach (1978). The data collection process involved interviews, observations, and documentation techniques. The analysis was conducted through several stages, including data reduction, presentation, and drawing conclusions. The results reveal that reflective practice enhances pedagogical competence by implementing high-quality, innovative, and creative teaching methods, particularly within the classroom setting. These findings have practical implications for the field practice of Islamic Religious Education teachers in schools. They serve as a valuable resource for teachers to develop new strategies in addressing challenges within the teaching and learning process, ultimately contributing to their professional growth and establishing cultural references.
Developing Akhlak Karimah Values through Integrative Learning Model in Madrasah
Authors: Arifin Syamsul , Huda Miftachul , Mufida Nur Hayati
Published: June 2023

The primary objective of this study was to examine a holistic learning approach that promotes the development of noble character values (akhlak karimah) in madrasah. The study employed a qualitative methodology, specifically utilizing phenomenological research and a descriptive method. Data collection involved interviews, observations, and examination of relevant documents. The participants in this research were Madrasah teachers responsible for teaching various subjects at the ibdtida'iyah, tsanawiyah, and aliyah levels in Lombok. The findings revealed the development of a learning model that integrates all aspects of education to foster the exploration of akhlak karimah values, which are defined as objectives in the affective domain. These values were identified based on the students' needs and were subsequently incorporated into the curriculum through student-centered integrated learning. The implementation of the proposed model follows a similar pattern and concludes with a dedication to this approach.
Module-Based Training for Teacher Professional Development in Madrasah
Authors: Latuapo Ridhwan
Published: June 2023

In the era of Industry 4.0, teachers are expected to exhibit a professional attitude in fulfilling their educational responsibilities. Despite their involvement in numerous activities, the level of professionalism among teachers has not seen significant growth. This research aims to analyze the effectiveness of using the SKI (Sejarah Kebudayaan Islam/Islamic Culture and History) Module in enhancing the professionalism of SKI teachers. The study was conducted in a madrasah affiliated with the Ministry of Religion in the Maluku Province. A total of 20 SKI teachers from the madrasah in Ambon City and Central Maluku Regency were selected as research participants. The research utilized a quantitative-qualitative approach, collecting data through observations, interviews, and product assessments. The results indicated that the module's validity score was 90.38, indicating high validity. The product rating was 3.563.56, demonstrating a very high level of quality. Additionally, the assessment of learning tool preparation scored 7.84, representing a high level of proficiency. The mastery of learning material achieved a score of 82.04, signifying a very high level of competence. The preparation of research proposals scored 69.269.2, indicating a medium level of readiness. Overall, the findings suggest that training using modules can effectively enhance the professionalism of SKI teachers within the Ministry of Religion in the Maluku Province.
Perceived Usefulness and Perceived Ease of Use of Online Learning for Islamic Religious Education Teacher
Authors: Siregar Hariman Surya
Published: June 2023

The primary objective of this study is to examine how the perceived ease of use and usefulness of online learning, specifically using the SPACE (Sistem Pembelajaran Agama Cara Elektronik/Electronic Way of Religion Learning System) platform, impact the effectiveness of teaching professional education students. The study employs a mixed-methods approach, combining both qualitative and quantitative methods, and utilizes descriptive techniques. The research instruments utilized include interview forms and the TAM (technology acceptance model) questionnaire, which assess the participants' perceptions of the ease of use and usefulness of online learning. The research sample was selected using purposive sampling. Data analysis involved the utilization of multiple linear regression analysis. The findings of the study indicate a notable and significant influence of the perceived ease of use and usefulness of online learning. This is supported by the observation that the graduation rate of professional education students who acquire teacher professional certificates increased by 14.77% as a result.
The Effect of Triangulation-Based Metacognitive Learning Strategy on Students' Chemistry Literacy and Learning Achievement
Authors: Parlan Parlan , Minata Zelen Surya , Suryadharma Ida Bagus , Sulistina Oktavia , Marfu'ah Siti
Published: June 2023

This study aimed to investigate the effect of triangulation-based metacognitive learning strategy on students’ chemistry literacy and learning achievement. This study was conducted by using a pretest-posttest control group design. The participants of this research were two classes of 10th grade natural science students of Senior High School in Pasuruan, Indonesia. One class was taught using triangulation-based metacognitive learning strategies consisting of four steps (Preparing, Doing, Checking, and Assessing & Following-Up) abbreviated to MLS-PDCA, and another was taught using expository learning strategy (ELS). Data was collected by pretest and posttest. Based on the data analysis, it was known that the N-gain averages of students’ chemistry literacy were 54% in MLS-PDCA class as the middle category and 38% in the ELS class as middle category. N-gain averages of learning achievement were 56% in experiment class as middle category and 40% in ELS as middle category. Mann Whitney U and independent sample t-test showed that the improvement of students’ chemistry literacy and learning achievement in MLS-PDCA class was more significant than in the ELS class. It can be concluded that MLS-PDCA can enhance the students’ chemistry literacy and learning achievement in senior high school.
Pre-Service Chemistry Teacher’s Conception About Chemistry of The Rare Earth Elements
Authors: Pinasti Titen , Mudzakir Ahmad , Hernani Hernani
Published: June 2023

Rare Earth Elements (REE) is an interesting chemistry topic, especially due to current technology development. However, new learning designs of REE need to be developed for Pre-service Chemistry Teachers (PCT) as it is not yet available. A good design is constructed by analyzing PCT pre-conceptions based on the technical difficulties faced by the students during teaching process. The study aims to identify PCT's pre-conceptions focusing on REE topic. We conducted this research involving 17 chemistry education students at the Universitas Pendidikan Indonesia, Bandung. Data was collected through interviews and analyzed using the Qualitative Content Analysis (QCA) method. Our results highlight that PCT had difficulties with chemistry content of REE, especially about electronic configuration, magnetic, and luminescence properties. In addition, PCT faced difficulties correlating electronic configuration's chemistry content into contexts. Based on the interview results, 88.2% of the students agree with the development learning design for undergraduate chemistry students. As a result, we conclude that technical difficulties and misconceptions about REE can be overcome by developing the learning design based on the need of the students.
Implementation of STEM E-Module with SDGs Principle to Improve Science Literacy and Environment-friendly Attitudes in Terms of Gender
Authors: Aswirna Prima , Kiswanda Vira , Nurhasnah Nurhasnah , Fahmi Reza
Published: June 2023

Scientific literacy plays an important role in developing education in the 21st century. However, the current student’s scientific literacy ability is relatively low. The millennial generation has been named as a generation that has an environment-friendly attitude. In cases that occur in the field, many students still litter and are not friendly to the environment. There are no teaching materials that develop scientific literacy and environment-friendly attitudes in implementing STEM (Science, Technology, Engineering, and Mathematics) with the principles of Sustainable Development Goals (SDGs). This research aims to produce a STEM e-module with the principles of SDGs to improve scientific literacy and environment-friendly attitudes of 11th grade students regarding gender that is valid, practical, and effective. This research is development research (R&D) with the Plomp model. The data analysis results show that the STEM e-module with SDGs principle has a good impact on students' scientific literacy skills and environment-friendly attitudes. The developed e-module can also help students practice scientific literacy and improve a better environment-friendly attitude.