bluuebunny/crossref_metadata_2025 huggingface dataset:
Роль органической дисфункции головного мозга в формировании неорганического энкопреза в детском возрасте
Authors: Бебенин А.А.
Published: January 2021

В статье представлены результаты долгосрочного изучения неорганического энкопреза в детско-подростковом возрасте. Цель: изучение факторной обусловленности неорганического энкопреза, основанной на систематизации и анализе данных комплексного клинико-параклинического исследования (анамнестического, неврологического, электрофизиологического, нейропсихологического исследований). Материал и методы. В исследовании рассматривались 192 случая неорганического энкопреза с затяжным неблагоприятным течением. В исследовательскую выборку включены дети, страдающие энкопрезом неорганической природы (F98.1 по МКБ-10), в возрасте от 5 до 13 лет, с общим интеллектуальным показателем по шкале Векслера не ниже среднего уровня (90‒109 баллов). Все дети обследованы педиатром и гастроэнтерологом для исключения патологии желудочно-кишечного тракта. Сравнение проведено с аналогичными показателями одновозрастных групп детей и подростков (n=100) ‒ контрольная группа. В качестве основного метода применялся клинический с целью установления клинико-психопатологических, клинико-динамических закономерностей развития неорганического энкопреза. По результатам компьютерной ЭЭГ были верифицированы нарушения биоэлектрической активности головного мозга. Результаты. Комплексное клинико-параклиническое исследование продемонстрировало, что формирование энкопреза обусловлено резидуально-органической церебральной недостаточностью вследствие влияния патогенных факторов на раннем этапе онтогенеза (пренатальный и перинатальный периоды), выявленной в 100% случаев. Достоверность органической дисфункции головного мозга при энкопрезе верифицирована данными неврологического, электрофизиологического, нейропсихологического исследований. Соотнесение отчетливых эпилептиформных паттернов ЭЭГ с клиническими проявлениями психоорганических нарушений свидетельствует о том, что в развитии энкопреза с затяжным неблагоприятным течением участвуют механизмы, схожие с эпилептогенезом.
Интервью культуральной оценки в диагностике состояния психического здоровья: результаты международного полевого испытания в Нидерландах
Authors: Рохлоф Х. , ван Дейк Р.С.Дж. , Грюн С.П.Н. , Аггарвал Н.К. , Льюис-Фернандес Р.
Published: January 2021

Введение. Вопросам, связанным с культуральной обусловленностью психики, уделяется всё больше внимания в связи с ростом культурного разнообразия общества в результате усилившихся в последние десятилетия потоков миграции во всем мире. В рамках редакционной доработки представлений о взаимосвязи культуры и психики в DSM-Ⅴэкспертная секция по кросс-культуральным вопросам разработала Интервью культуральной оценки (Cultural Formulation Interview ‒ CFI) из 16 вопросов, предложенное использовать в диагностике состояния психического здоровья. Дополнением к DSM-Ⅴслужит подготовленное недавно коллективом авторов второе издание Клинического руководства по культурной психиатрии. Руководство подготовлено в соответствии с принципами, изложенными в DSM-V, где предлагается подробная инструкция по применению интервью по проблемам, связанным с культурной средой при постановке диагноза (Clinical Manual of Cultural Psychiatry, 2015). Цель: определение восприятия CFI пациентами (n=30) и клиницистами (n=11) по параметрам: удобство и простота в выполнении, приемлемость и клиническая полезность. Исследование проводилось как часть масштабного международного клинического полевого испытания в пяти странах. Более ранние исследования обнаружили, что этническое многообразие психиатрической популяции в Нидерландах имеет тенденцию ограничивать коммуникацию в сфере психического здоровья и уменьшать точность постановки психиатрического диагноза. Полуструктурированные интервью разработаны в Нидерландах с целью определения культуральных проблем при психодиагностической оценке. Результаты. 11 нидерландских клиницистов после обучения применению CFI в рамках структурированной программы провели 30 интервью в двух группах: 1-я группа ‒ пациенты иностранного происхождения, 2-я группа ‒ пациенты-коренные жители Нидерландов. Клиницисты и пациенты использовали количественные и качественные опросники до и после назначения CFI. Пациенты и клиницисты положительно оценили удобство, простоту выполнения и приемлемость CFI. Пациенты более позитивно оценили клиническую полезность CFI по сравнению с клиницистами. Применение клиницистами CFI не приводило к изменению диагнозов психических расстройств в связи с идентичной оценкой уровня психического здоровья в разных институтах Нидерландов. Таким образом, CFI является удобным и простым в выполнении, приемлемым и потенциально клинически полезным инструментом в психиатрической практике. Его использование расширяет возможности стандартного психиатрического обследования пациентов с диагностическими и коммуникативными проблемами.
Иммунопатология при шизофрении: итоги исследования в НИИ психического здоровья Томского НИМЦ
Authors: Ветлугина Т.П.
Published: January 2021

В статье приводится анализ исследований состояния системы иммунитета при шизофрении, проведенных в НИИ психического здоровья Томского НИМЦ с 1981 г. по 2020 г. Кратко освещены основные направления: трансрегиональные исследования специфического иммунитета к широко распространенным вирусам и состояния системы иммунитета у больных шизофренией; накопление данных в рамках психонейроиммунной гипотезы шизофрении; изучение вклада иммунных механизмов в адаптациогенез при шизофрении; исследование психонейроиммуномодулирующих эффектов спектра атипичных нейролептиков; разработка способов прогнозирования эффективности терапии и методов лечения больных шизофренией с включением иммуноактивных препаратов.
Алкогольная фракция как паттерн смертности от туберкулеза в России
Authors: Разводовский Ю.Е. , Зотов П.Б.
Published: January 2021

Туберкулез наносит губительный социальный и экономический вред обществу и является причиной преждевременной смертности значительной части трудоспособного населения. Цель исследования: оценка алкогольной фракции в структуре смертности от туберкулеза в России на основе популяционной базы данных. В настоящем исследовании оценена алкогольная фракция и определена её роль в структуре смертности от туберкулеза в России с использованием популяционных данных за период с 1980 г. по 2015 г. Оценка связи между динамикой уровня потребления алкоголя (независимая переменная) и уровня смертности от туберкулеза (зависимая переменная) проводилась с помощью метода авторегрессии ‒ проинтегрированного скользящего среднего. В соответствии с результатами произведенной оценки потребление алкоголя тесно ассоциируется с уровнем смертности от туберкулеза как среди мужчин, так и среди женщин. Оценка алкогольной фракции показала, что вклад алкоголя в уровень смертности от туберкулеза среди мужчин и женщин составил соответственно 59,2% и 43,4%. Результаты настоящего исследования говорят о том, что популяционный уровень потребления алкоголя является четким предиктором уровня смертности от туберкулеза в России.
Методы диагностики лекарственно-индуцированного паркинсонизма: обзор отечественной и зарубежной литературы
Authors: Вайман Е.Э. , Шнайдер Н.А. , Незнанов Н.Г. , Насырова Р.Ф.
Published: January 2021

Введение. Лекарственно-индуцированный паркинсонизм (ЛИП) относится к группе вторичного паркинсонизма, занимая второе место после болезни Паркинсона (БП). Распространенность ЛИП в мире достигает 36%. ЛИП характеризуется появлением акинетико-ригидного синдрома с наличием типичной триады (акинезия, брадикинезия, тремор) у пациентов на фоне приема лекарственных препаратов, влияющих на выработку дофамина. Цель. Анализ международных шкал и опросников, используемых для диагностики лекарственно-индуцированного паркинсонизма. Материалы и методы. Проведен поиск полнотекстовых публикаций на русском и английском языках по базам данных eLibrary, PubMed, Springer, Clinicalkeys, Google Scholar, используя ключевые слова и комбинированные поиски слов (лекарственно-индуцированный паркинсонизм, антипсихотики, шкалы, тесты и опросники, диагностика ЛИП), за последнее десятилетие. Кроме того, в обзор включались более ранние публикации, представляющие исторический интерес. Несмотря на всесторонний поиск по этим часто используемым базам данных и поисковым терминам, нельзя исключать, что некоторые публикации могли быть пропущены. Результаты. В обзоре рассмотрены валидные шкалы и опросники, наиболее часто используемые и перспективные для применения при диагностике антипсихотик-индуцированного ЛИП. Заключение. Несмотря на синтез антипсихотиков Ⅱгенерации и внедрение их в реальную клиническую практику, проблема ранней диагностики и оценки динамики ЛИП при хронической терапии шизофрении остается актуальной темой исследований, но далекой от разрешения.
Перспективные терапевтические подходы к когнитивным расстройствам (роль пробиотиков в комплексном лечении): литературный обзор
Authors: Мякотных В.С. , Анохина М.В. , Сиденкова А.П. , Сердюк О.В. , Мельник А.А.
Published: January 2021

В статье представлен обзор современных научных отечественных и зарубежных публикаций, посвященных возможностям применения пробиотиков в терапии и профилактике возрастно-специфичной церебральной патологии. Высокая частота распространенности додементных когнитивных расстройств в контингенте лиц старших возрастных групп, значимый риск их трансформации в деменцию, ограниченные протекционные возможности классических терапевтических схем в совокупности определяют необходимость поиска современных стратегий помощи, направленных на снижение темпа старения ЦНС и предотвращение формирования его патологических форм. Патогенетическая многофакторность проблемы патологического старения ЦНС, современные знания о значительном вкладе в него механизмов нейровоспаления, дисфункциональности оси «микробиота – кишечник – мозг», потенциальная возможность коррекции состава микробиоты посредством введения пробиотиков – всё это позволяет рассматривать пробиотические препараты как перспективный терапевтический ресурс профилактики церебральной патологии. Цель исследования: выявление возможностей использования пробиотиков в профилактике и лечении заболеваний центральной нервной системы. Материалы исследования: научные публикации, посвященные освещению роли пробиотиков в комплексном лечении когнитивных расстройств. Применен общенаучный метод: анализ современной научной отечественной и зарубежной литературы по проблеме исследования, обобщение, сравнение, систематизация теоретических данных об опыте применения, оценка эффективности пробиотических средств в терапии когнитивных расстройств и проявления их протективного, ЦНС-ориентированного действия. Представленный анализ теоретических предпосылок применения пробиотиков при психических расстройствах, механизмов протективного действия пробиотиков на головной мозг, терапевтической эффективности применения пробиотиков свидетельствует о нормализующей роли пробиотиков на микробиом хозяина, снижении нейровоспаления при старении ЦНС. Выявлены задачи и перспективы будущих исследований применения пробиотиков у пациентов с когнитивными расстройствами.
Improvement of roasted germinated brown rice flour processing using ergothioneine to limit oxidation during processing and preservation
Authors: Truc H.T. , Trung P.Q. , Ngoc N.T.L. , Binh N.D.T. , Duy L.N.D. , Ngoc T.T.A. , Ha N.C.
Published: January 2021

Roasting temperature and time are important parameters in the process of roasted
germinated brown rice flour (RGBRF), which cause the loss of bioactive ingredients and
sensory value of the product. During roasting and storage, fat oxidation is also one of the
problems that reduce the quality of RGBRF. In order to complete the RGBRF process,
experiments using different temperature and time as 160oC, 200oC, 240oC for 10 to 30
mins were done to find the best roasting conditions. To limit the oxidation of fat during
the processing and preserving RGBRF, ergothioneine (ERG) extract from enoki
mushroom were supplemented at 3%, 5%, 7% and 10% (w/w) before roasted, the product
was then ground and put into two types of packaging (PA and aluminum), vacuum seamed
and stored at room temperature for 8 weeks were carried out. The results showed that
germinated brown rice (GBR) which supplemented 3% of the extract before roasted at
200oC for 30 mins showed the best quality in term of sensory value, γ-aminobutyric acid
(GABA) content and helped to limit fat oxidation as well as maintained stable quality after
8 weeks of storage in PA and aluminum packaging. In addition, the results from in vitro of
starch resistance and in vivo of sugar absorption capacity in rats showed that RGBRF did
not significantly change the GI index as well as the ability to absorb sugar compared to
unroasted product. The results indicated that RGBRF should be used as a nutritious food
with the ability to supplement bioactive compounds to the people at risk of lifestyle
diseases.
The Importance of Collaborative Designed-led Research for Culturally Diverse Communities
Authors: Marques Bruno
Published: January 2021

No description supplied
Revalidation Physical Self-Perceptions: A Cross-Cultural Assessment in Indonesian Children
Authors: Sobarna Akhmad , Hamidi Ahmad , Bunyami Agus Ahmad , Muharam Asep Nirwan , Sunarsi Denok
Published: January 2021

The purposes of this research was to examined the cross-cultural validity of the Physical Self-Perception Profile for Children (PSPP-C), an instrument for assessing physical self-esteem, in Indonesian children. The inventory comprises 36-items designed to measure six constructs from a hypothesisedÂ  multi-dimensional, hierarchical model of physical self-perception. Two hundred and fifty two children, aged 13 to 14 years, from a secondary school in Bandung- West Java completed the PSPP-C inventory. Descriptive statistics revealed mean construct scores to be comparable with results from other studies. Factor analysis of the inventory items supported a four factor structure and Cronbach alphas confirmed its internal consistency. The hierarchical structure of the underlying model was supported by partial correlation analysis. The PSPP-C exhibited satisfactory validity and reliability for use with children from Indonesia, but caution must be exercised when interpreting some of the subdomains due to discrepancies in the factor structure. The authors also express reservations concerning the indiscriminate use of such psychometric inventories across different cultures.
Serum albumin assay – easy or problematic analysis?
Authors: Filípek Jaroslav , Illek Josef
Published: January 2021

Serum albumin determination is an important biochemical investigation in clinical laboratories. Photometric methods using albumin binding to organic dyes – bromocresol green (BCG) or bromocresol purple (BCP) – are most commonly used. These determinations are quick, simple, and inexpensive. They are, however, associated with a number of problems. Discussions on the methodological unification and use of BCP are ongoing in human laboratory medicine. The reaction of human albumin with this dye is more specific. On the other hand, its affinity for animal albumin is significantly lower, for which reason BCG is used in veterinary medicine. However, due to the lower reaction specificity of this dye, the results are slightly overestimated as the dye reacts to a lesser extent with alpha and beta globulins. This disadvantage can be largely eliminated by reducing the incubation time to about 30 s. Another problem is the method calibration. Some laboratories use species-specific albumin as calibrators, but this is technically challenging for a laboratory that analyzes albumin of many species. We therefore recommend using a commercially available calibrator that is traceable to the European Reference Material for Specific Proteins. We consider these following principles – using BCG, shortening the incubation time to 30 s and using the mentioned calibrator – as a basic condition to obtain clinically correct and inter-laboratory comparable results.
Effect of sperm concentration on boar spermatozoa mitochondrial membrane potential and motility in semen stored at 17 °C
Authors: Wysokińska Anna
Published: January 2021

The aim of the study was to assess the effect of sperm concentration in the ejaculate on the mitochondrial membrane potential and motility of Landrace boar spermatozoa during storage of diluted semen at 17 °C. The study was conducted on ejaculates collected from 10 boars aged 1.5–2 years. Based on sperm concentration measurements, two groups of boars were identified: Group 1 – boars providing ejaculates with a sperm concentration of at least 500 × 103/mm3 and Group 2 – boars providing ejaculates with a sperm concentration of less than 500 × 103/mm3. Four ejaculates were collected manually from each boar. Each ejaculate was diluted with Biosolvens Plus diluent, and insemination doses were prepared and stored at 17 °C. Mitochondrial membrane potential and motility of spermatozoa were evaluated at each insemination dose. The tests were carried out after 1, 24, 48, 96 and 168 h of storage. Based on the results, it was found that ejaculates with a sperm concentration ≥ 500 × 103/mm3 have a lower share of spermatozoa with high mitochondrial membrane potential than ejaculates with a sperm concentration below 500 × 103/mm3. A high correlation between the share of spermatozoa with a high mitochondrial membrane potential and motility of spermatozoa was demonstrated in the first 24 h and after 96 h of semen storage, which was confirmed by the calculated phenotypic correlation coefficients. Sperm cells in ejaculates with a higher sperm concentration are more sensitive to storage time than spermatozoa in ejaculates with a lower concentration.
Patho-anatomic findings in finisher pigs, sows, and piglets detected during veterinary slaughterhouse inspection
Authors: Večerek Vladimír , Voslářová Eva , Semerád Zbyněk
Published: January 2021

The number of patho-anatomic findings detected during the veterinary examination of slaughtered pigs was analyzed. From 2010 to 2017, a total of 20 550 072 finisher pigs, 484 710 sows, and 94 279 piglets were slaughtered in the Czech Republic. By comparing the overall amount of patho-anatomic findings expressed as an index of the ratio of the number of findings to the number of slaughtered animals, the highest incidence of patho-anatomic findings was determined in piglets (index 1.52), followed by sows (index 1.23), and the lowest in finisher pigs (index 0.81). The most numerous was the occurrence of chronic findings (finisher pigs: index 0.724%, sows: 0.926, piglets: 0.877). Furthermore, a high frequency of acute findings was found (finisher pigs: index 0.037, sows: 0.207, piglets: 0.373). The findings of traumatic and parasitic nature were significantly (P < 0.001) lower than those of chronic and acute character. The differences in the total number of findings and in the number of findings by the type of damage were significant (P < 0.001) between the individual pig categories. The results show that the worst health condition was observed in piglets, followed by sows, and the best in finisher pigs. Furthermore, the number of findings was significantly decreasing in finisher pigs (r = -0.7143, P = 0.047); no significant change was found in sows (r = -0.643, P = 0.086); however, it was significantly increasing in piglets (r = +0.857, P = 0.007). Therefore, there is a particular need for health improvement in piglets and also in sows.
A multiannual survey of cadmium content in pig tissues collected in the Czech Republic during the years 2015–2019
Authors: Svoboda Martin , Drápal Jiří , Haruštiaková Danka , Svobodová Zdeňka
Published: January 2021

The assessment of cadmium content in the muscle, liver and kidneys of fattening pigs and sows was conducted in the Czech Republic during the period of 2015–2019. The samples were collected from a total of 32 sows and 210 fattening pigs. The mean cadmium content in the livers and kidneys of all sows was 0.102 ± 0.010 and 0.361 ± 0.032 mg·kg-1, respectively. The mean cadmium content in the livers and kidneys of all fattening pigs was 0.028 ± 0.001 and 0.141 ± 0.005 mg·kg-1, respectively. The maximum residual limit for human consumption was not exceeded in any sample. The cadmium content in the liver did not differ significantly between sows and fattening pigs in any particular year. In contrast, the cadmium content in kidneys differed significantly between sows and fattening pigs, being higher in sows (P < 0.05). No significant decreasing trend was observed for the cadmium content in tissues during the whole time period. It can be concluded that there is a need for further monitoring of the cadmium content in pig tissues in the Czech Republic.
Clinical and laboratory outcome after surgical treatment of single congenital extrahepatic portosystemic shunt using ameroid constrictor in 25 dogs
Authors: Nečasová Andrea , Lorenzová Jana , Stehlík Ladislav , Proks Pavel , Filipejová Zita , Nečas Alois
Published: January 2021

The objective of the study was to evaluate the clinical and laboratory outcome after the surgical treatment of a single congenital extrahepatic portosystemic shunt using an ameroid constrictor. Patient medical records were reviewed in retrospect. Data on the signalment, clinical signs, preoperative bile acid stimulation test and ammonia concentration were recorded. The surgical treatment success rate was evaluated by mortality in the perioperative and short-term postoperative period and by the long-term clinical outcome. Bile acid stimulation test and ammonia concentration were also analysed 2–3 days, 4–6 weeks, and 6–8 weeks postoperatively. No patient died in the selected periods. The long-term clinical outcome was excellent in 15 out of 20 patients, good in 3 out of 20 patients and poor in 2 out of 20 patients. Preprandial bile acid concentration was elevated in 96.00%, postprandial bile acid concentration in 100.00% and ammonia concentration in 80.95% of patients preoperatively. A significant decrease was found in postprandial bile acid and ammonia 2–3 days postoperatively and in preprandial bile acid 4–6 weeks postoperatively. A significant decrease in liver function parameters in days post operation indicates a rapid restoration of hepatic function. The surgical treatment of a single extrahepatic portosystemic shunt using an ameroid constrictor is a successful method of treatment for this type of portosystemic shunt, with as much as 75.00% of the patients having an excellent long-term clinical outcome.
Laparoscopic left hemihepatectomy in small dogs: an easy and effective new technique
Authors: Zhang Hua , Wang Jing , Cao Yaqin , Zhang Zhao nan , Shen Jing , Tong Jinjin , Wang Hong bin
Published: January 2021

The present report describes a novel approach to and presents the surgical results for laparoscopic hepatectomy of the left lobes in small dogs. A purely laparoscopic four-port approach was used in seven beagles. The left triangular ligament was cut first, then the base of the left medial lobe (LMB) was ligated with silk thread using a needle, and the liver parenchyma of the LMB approximately 0.5 cm above the ligation site was removed with LigaSure. The left lateral lobe (LLB) was removed in the same manner. Blood was collected on postoperative days 1, 3, 7, and 14 for laboratory testing. Left hepatic lobe resection was successfully completed in all dogs, with an average operation time of 102.53 ± 9.07 min and an average blood loss of 32.10 ± 6.43 ml. Serious postoperative complications were not observed. The white blood cell (WBC) count and alkaline phosphatase (ALP) level were significantly increased in experimental dogs 1 day after surgery (P< 0.05); aspartate transferase (AST) and alanine transaminase (ALT) were significantly different before and after surgery (P< 0.01); and all the indicators were basically normal seven days after the operation. Exploratory laparoscopy at 28 days revealed adhesion of the surface of the liver section to the omentum or the gastric wall, but there were no other abnormal findings. The combined application of liver pedicle ligation and LigaSure for liver lobectomy provides a simple and effective method for generating liver lobectomy models for research on liver disease and regeneration and a feasible laparoscopic liver lobectomy operation scheme for small dogs (10–15 kg).
The effect of capsaicin and diethylnitrosamine on mouse nephrotoxicity, hepatotoxicity and hepatocarcinogenesis
Authors: Kuchařová Kumžáková Vendula , Veselá Ivana , Škorič Miša , Daněk Ondřej , Řeháková Kristína , Tomenendálová Jaroslava
Published: January 2021

Diethylnitrosamine is well known for its toxic and carcinogenic properties affecting mainly liver and kidneys. Capsaicin has been proven in previous years as a promising protective agent against many health problems affecting modern people. In this study we used diethylnitrosamine induced mouse experimental model of liver and kidney damage to assess the potential chemopreventive effect of capsaicin in vivo. Fifty female ICR mice were randomly divided into five groups intraperitoneally administered 1% ethanol solution in controls, capsaicin to assess its toxicity, diethylnitrosamine alone, and diethylnitrosamine and capsaicin in combination in different manners in two groups. After 14 weeks all mice were sacrificed, complete necropsy was performed and liver and kidneys were used for further examination. Slides of both organs stained with haematoxylin and eosin were histologically evaluated and immunohistochemical detection of proliferating cell nuclear antigen and glutamine synthetase in the liver tissue was performed. Histological evaluation of the liver and kidneys revealed toxic damage of diethylnitrosamine treated animals, whereas mice that received the combination of the substances showed milder lesions. Proliferating cell nuclear antigen expression was lower in diethylnitrosamine treated animals compared to the control and capsaicin groups, pointing to a disruption of the proliferative activity of hepatocytes in the juvenile liver. Glutamine synthetase expression did not differ between the groups, indicating that no tumours were induced by any of the substances used in our study. In conclusion, our experiment demonstrated the toxic properties of diethylnitrosamine in mice liver and kidneys, with the promising beneficial effect of capsaicin.
Printable Table of Contents. JITE: Research, Volume 20, 2021
Authors: Cheong Christopher
Published: January 2021

Table of Contents for JITE: Research, Volume 20, 2021
RELATIONSHIP ADVERTISING AND INFORMATION ACTIVITIES AND BRANDING IN MODERN RETAIL ESTABLISHMENT
Authors:   Russian University of Cooperation, Matveeva O.Z.
Published: January 2021

The relevance and рurpose of the work. The relevance of the topic chosen due to the fact that advertising and branding have become a prerequisite for a successful business in today's retail outlets. Of the entire set of market instruments Russian business quickly mastered and became widely used innovative approaches to advertising and information activities with the use of various advertising media, as well as promoting the brand of the enterprise. The purpose of the work is to identify advertising tools that increase sales efficiency and their relationship with the brand of a trading company.
INTELLECTUAL CAPITAL OF THE UNIVERSITY: APPROACHES TO STRUCTURING AND CLASSIFYING KEY ELEMENTS
Authors:   Financial University under the Government of the Russian Federation, Tolstikova E.A.
Published: January 2021

Against the background of the formation of the knowledge economy, intellectual capital, and the ability to properly manage it become one of the key elements of the economic ecosystem. Universities, as the backbone organizations of the knowledge economy infrastructure, should demonstrate the most effective ways and methods of forming and managing intellectual capital. The purpose of the article is to describe the existing approaches to structuring the intellectual capital of the university and to propose the most effective approach to improve the quality of the infrastructure of the knowledge economy in universities. As a result of the study, the structure of the university’s intellectual capital is proposed in the context of improving the quality of intellectual capital management. It was concluded that the indicators of the development of the knowledge economy at the global and regional levels and the indicators of university performance used in international studies actually have common approaches and reflect the level of development and involvement of intellectual capital in the development of the system under study (region or university). To ensure effective operation, universities need to guarantee high-quality management of intellectual capital and to ensure the formation of a stable system for monitoring the state of its elements. The main objects of management in this case will be the talent of the staff and students of the university and the innovative infrastructure of the university.
PUBLIC PROCUREMENT AS A TOOL OF MACROECONOMIC POLICY (BASED ON THE MODEL OF «AGGREGATE DEMAND – INFLATIONARY ADJUSTMENT» AD-IA)
Authors:   Financial University under the Government of the Russian Federation, Fedorova I.Yu. , Matevosyan S.M. ,   Financial University under the Government of the Russian Federation, Rachek M.S. ,   Financial University under the Government of the Russian Federation
Published: January 2021

The article considers the application of the Keynesian model of aggregate demand – inflationary adjustment on the example of data analysis of changes in the macroeconomic parameters of the economic development of the Russian Federation. It describes and proves the relationship between the level of gross domestic product, total domestic consumption, investment and net exports due to changes in the amount of public procurement in different periods. The theoretical justifications for the model’s action due to changes in the inflationary setting are revealed, and the assumption about changes in inflation due to changes in the gross domestic product is expressed and verified (the reverse situation). The theoretical conclusions are supported by appropriate graphical methods of presenting information for greater clarity.
IMPROVING THE FUNCTIONING OF THE «PRODUCTION – LOGISTICS – SALES» SUBSYSTEMS IN MODERN CONDITIONS
Authors:   LLC «PHILIPS», Paskevskaya V.N.
Published: January 2021

Abstract. The article deals with the subsystem of interrelated processes of production, logistics and marketing. The features of their development in modern conditions are revealed. The ways of implementation of individual strategies and the development of subsystems.
OPPORTUNITIES FOR IMPLEMENTING LARGE STATE OIL PROJECTS UNDER VARIOUS SCENARIOS OF OIL PRICE CHANGES
Authors:   RUDN University, Mazurchuk T.M.
Published: January 2021

The scientific work studies the influence of the dynamics of prices for hydrocarbons on the possibilities of implementing state projects in the oil industry of Russia. Also, the economic efficiency of oil projects in the Russian Federation is assessed under various cost scenarios, both in the short and long term. The aim of the study, the authors set out to build an objective model for the implementation of Russian state projects in the oil industry, based on 3 scenarios of changes in hydrocarbon prices until 2023 according to: basic, optimistic and pessimistic forecasts. The paper studies the experience of creating large oil projects in modern Russia and in other countries; the authors pay special attention to oil projects during periods of turbulence in oil price quotations, during the economic recessions of 2008, 2014–2016 and 2020. The prospects for the completion of current projects in Russia are also being assessed in the face of oversupply on hydrocarbon markets and turbulent prices for well-known oil brands. The scientific basis of the work is Russian and foreign sources, assessments of experts from the oil and gas complex of Russia and countries-exporters of hydrocarbons, analytics and reports of oil companies, state programs for the development of the oil industry of the Russian Federation and statistical bases of state statistics services. To construct objective development scenarios, forecasts were used from sources such as: the Ministry of Energy of the Russian Federation, the Ministry of Economic Development, the Central Bank, the BP Statistical Database and the World Bank data, forecasts of large oil companies in Russia.
SUSTAINABLE FINANCE in Canada
Authors:   Russian Academy of Sciences, Khoroshilov E.E.
Published: January 2021

The article analyzes Canadian sustainable development policy and Canada’s experiences in implementing sustainable financing mechanisms. It is concluded that accelerated development of sustainable financing mechanisms is favored by large Canadian financial institutions based mainly in the provinces of Ontario and Quebec. It is also noted that sustainable finance will increasingly discriminate in terms of access to financial resources enterprises, industries, regions and countries that do not meet the criteria of sustainability. Sustainable finance mechanisms could be also used as instruments of interstate, intersectoral and corporate competition.
COVID-19 PANDEMIC AS A DRIVER OF DIGITAL COMMUNICATIONS GROWTH IN THE PHARMACEUTICAL MARKET
Authors:   Financial University under the Government of the Russian Federation, Makarova E.V. , Sinyaeva I.M. ,   Financial University under of the Government of the Russian Federation,
Published: January 2021

The impact of the COVID-19 pandemic on the development of the pharmaceutical market is analyzed. In addition to serious losses, the current situation also provided an opportunity for development. First of all, this has affected communications, which have almost completely switched to digital format. The technical capabilities and skills of using digital technologies of all participants in the pharmaceutical market - patients, doctors, pharmacies, pharmaceutical companies, government, showed who was ready to accept the current reality, and who was left out of work. Also, the current situation has further exposed the problems that exist in the pharmaceutical market. A good example is pharmaceutical companies that have switched to remote communication. For some companies, this was not difficult, because previously these companies, understanding the prospects for interaction through digital communications, have already created departments that fully interact with customers through digital technologies. Those who did not pay attention to the development of digital promotion channels had to quickly rebuild, while there were problems with technical equipment, the ability to use it by the company’s employees, and most importantly – online meeting is different from an offline meeting. Also, not all clients were ready to interact in an online format. And if earlier they asked, for example, to send information by email, then started the complete remote work, everyone had to know various systems for meet remotely.
THE INFLUENCE OF M-COMMERCE SERVICE AND SYSTEM QUALITY DIMENSIONS ON OVERALL PERCEIVED SERVICE QUALITY
Authors: Salameh Anas Abdelsatar , Hassan Shahizan Bin , Alekam Jamal Mohammad
Published: January 2021

Information Technology (IT) has an increasing importance and development in business life. Nowadays, businesses have been seeking to reach their customers through m-services especially m-commerce. The concern is to what extent this m-commerce system can satisfy the consumers’ needs and contributes to the overall online purchasing development. This study aims to examine the effect of m-commerce service quality dimensions (website design, responsiveness, and trust), and system quality dimension (accessibility) on overall perceived service quality in m-commerce by customers. The data were collected from the Arab Open University in Jordan through a self-administered questionnaire, in order to test the hypotheses of the proposed model. 618 of questionnaires were used for analysis data, out of 870 distributed. The result of this study revealed that there are a significant effect of responsiveness and accessibility on overall perceived service quality. This study has some important implications for business practice and research.
GROWTH OF TERMINALIA BELLIRICA [(GAERTN.) ROXB.] ON THE MALANJKHAND COPPER MINE OVERBURDEN DUMP SPOIL MATERIAL
Authors: Katare Jyotish , Pichhode Mohnish , Kumar Nikhil
Published: January 2021

Copper Mining at Malanjkhand copper mining project (MCP), Balaghat, Madhya Pradesh is a subsidiary of Hindustan Copper Limited (HCL), major source of copper and more than 70% is being contributed from this mines. Copper contamination issues are becoming increasingly common in India with many documented cases of copper metal toxicity in mining sites. Effect of Copper on vegetation was studies by growth of Baheda (Terminalia bellirica) with different combination of soil, copper over burden dump spoil and cowdung manure. This paper in brief reflected that the growth of this plant species significantly improved with the combination of soil and organic manure like cowdung applied in the different combination with copper mine overburden dump spoil material which will be helpful in the re-vegetation program of these type of wastelands.
RAMANUJAN’S SPT-CRANK FOR MARKED OVERPARTITIONS
Authors: Bhattacharjee Nil Ratan , Das Sabuj
Published: January 2021

In 1916, Ramanujan’s showed the spt-crank for marked overpartitions. The corresponding special functions ,  and are found in Ramanujan’s notebooks, part 111.

In 2009, Bingmann, Lovejoy and Osburn defined the generating functions for ,

and . In 2012, Andrews, Garvan, and Liang  defined the  in terms of partition pairs. In this article the number of smallest parts in the overpartitions of n with smallest part not overlined, not overlined and odd, not overlined and even are   discussed, and the vector partitions and - partitions with 4 components, each a partition with certain restrictions are also discussed. The generating functions  ,  , , ,  are shown with the corresponding results in terms of modulo 3, where the generating functions  ,  are collected from Ramanujan’s notebooks, part 111.  This paper shows how to prove the Theorem 1 in terms of ,Theorem 2 in terms of  and Theorem 3 in terms of  respectively with the numerical examples, and shows how to prove the Theorems 4,5 and 6 with the help of  in terms of partition pairs. In 2014, Garvan and Jennings-Shaffer  are able to defined the  for marked overpartitions. This paper also shows another results with the help of 6 -partition pairs of 3, help of 20 -partition pairs of 5 and help of 15 -partition pairs of 8 respectively.
ROLE OF REMOTE SENSING AND GEOGRAPHIC INFORMATION SYSTEM TO ANALYZE THE IMPACT OF CLIMATE CHANGE ON FOREST ECOSYSTEMS
Authors: Mohommad Shahid , Joshi Shambhu Prasad
Published: January 2021

Climate change is an inevitable process impacting the forest ecosystem. Various impacts like treeline shift, forest fires, and Species distribution are due to the effect of climate change. Green House Gases concentration in the atmosphere is increasing day by day due to anthropogenic activities. The pace of climate change is very alarming which will have the substantial impact on the forest ecosystem. Role of remote sensing and geographic information system in observing the forest ecosystem was reviewed. Spatio-temporal analysis of change in forest structure can be proficiently done with the help of remote sensing and geographic information system. Climate Change Mitigation programmes like Reducing Emissions from Deforestation and Forest Degradation (REDD-plus) can be implemented with the help of remote sensing and geographic information system. Baseline data generation using remote sensing and geographic information system can be useful in designing the policies for forest management and monitoring.
ASSESSMENT OF SMALL AND MEDIUM ENTERPRISES GROWTH IN PUNJAB STATE OF INDIA
Authors: Garg Ankit
Published: January 2021

A strong industrial base is required for the socially and economic development of any country. The paper explores the advantages and disadvantages of small and medium scale enterprises with a comprehensive review on various aspects of ICT adoption. The study addresses the ICT adoption in their Small and Medium scale enterprises. There is significant difference between the SMEs growth that employed ICT adoption and that did not employed ICT adoption. Small and Medium Enterprises are considered to be the backbone of Punjab Economy.
DILTIAZEM HCL MICROCAPSULES USING ETHYL CELLULOSE ETHER DERIVATIVE POLYMER AS RELEASE RETARDING AGENT: IN-VITRO CHAPTER
Authors: Shah KifayatUllah , Khan Gul Majid , Shah ShefaatUllah , Rehman Asim Ur , Wahab Abdul , Dilawar Naz , Khan Kamran Ahmad
Published: January 2021

This study presents sustained releasemicroencapsulation of Diltiazem HCL.

Its in-vitro dissolution study in phosphate buffer pH 7.4 as dissolution medium and in vivo behaviour in animal subjects. The microcapsules were prepared using polymers Ethocel 7P and Ethocel 7FP at two different drug to polymer (D: P) ratios i.e. 1:5 and 1:10 and the effect of concentration was observed on drug release behaviour. The prepared microcapsules were evaluated for different physical characteristics i.e. Bulk density, Tap density, Compressibility index, Hausner’s ratio and Angle of repose. Characterization of the developed microcapsules was carried out using Differential Scanning Calorimetery and Fourier Transform Infrared Spectroscopy while Scanning Electron Microscopy was performed to observe the morphology of the microcapsules. Model dependent and in dependent approaches were used to find out the drug transport mechanism and to compare the drug release profiles with standard formulation respectively.

All the formulations show anomalous, non-Fickian diffusion mechanism and the data was best fitted in Korsmeyer’sPeppas equation.

While carrying out in vivo studies, simple and rapid HPLC methods were developed which revealed optimum serum concentration (Cmax) levels for the developed microcapsules predicting least chances of side or adverse effects.
A STUDY ON POLYNOMIAL TERNARY SEMI RING
Authors: Rao T. Srinivasa , Rao D. Madhusudana , Kumar B. Srinivasa
Published: January 2021

In this paper we discussed about the polynomial ternary semiring and characterized them.
ADOPTION OF SMALL RUMINANTS’ FATTENING PACKAGE IN AGRO-PASTORAL AREAS, DUGDA DAWA DISTRICT, SOUTHERN OROMIA, ETHIOPIA
Authors: Ahmed Mohammed Abdulla
Published: January 2021

Many studies were conducted to identify determinants of adoption of crop base technologies and practices and improved seeds, and while few studies concerned on evaluation of extension services in terms of the clients’ need and interest or adoption of livestock technologies in agro-pastoral and pastoral context. In fact, livestock extension services in general in developing countries are less prioritized and thus livestock based technology services are rarely extended. Common livestock technologies which are promoted to livestock raisers are focused on feed, veterinary services, and improved management practices through the extension services of agricultural/pastoral offices and livestock development units. The case hereunder, is about agro-pastoralists extension services evaluative perception and small ruminant fattening package adoption. Hence, this study investigates agro-pastoralists’ perception on the extension services, small ruminant fattening package and intensity of adoption of small ruminants’ fattening package. The study is undertaken in DugdaDawaWoreda, Oromia Region, Ethiopia. The Woreda has agro-pastoral and pastoral production system. The data were collected from 151 randomly selected pastoralists and agro-pastoralists using structured interview schedule. Secondary data were collected from different sources to supplement the data obtained from the survey. In addition to quantitative data qualitative data also gathered. Prior to formal survey an informal survey was also undertaken by using group discussion and interview with key informants. Descriptive statistics such as frequency, percentage mean, standard deviation, Chi-square tests and t-test were employed. The Tobit model was also employed to determine factors influencing intensity of small ruminant fattening package adoption. This study identifies agro-pastoralists and pastoralists are poorly addressed and their need and interests are not considered in any extension programmes. The Tobit model output showed that, agro-pastoralists intensity of adoption of small ruminant fattening package is influenced by: perception on the availability of improved breed, perception on resources based conflicts, current management practices, total livestock holding of HHs and credit use and availability for veterinary purposes. Future extension activities and agencies, promoting fattening package in agro-pastoral and pastoral areas, should focus on targeting agro-pastoralists with low perception on the availability of better breed, information and demonstration on the improved management practices, revision of credit supply criteria, making awareness and demonstration of the significant importance of small ruminants in the agro-pastoral and pastoral income and livelihoods contribution is important.
PREVALENCE OF UNSOLVED DRINKING PROBLEMS FOR DUI DRIVERS REFERRED FOR MEDICAL EVALUATION IN SWITZERLAND
Authors: De Cesare M. , Jomini V. , Selz R. , Mangin P. , Vaucher P. , Favrat B. , Augsburger M.
Published: January 2021

Estimate the proportion of heavy DUI offenders who do not initiate a treatment for their drinking problem before referring to an official medical expertise to recover their driver’s license. Evaluate the proportion of offenders with drinking problems who became abstinent during 6 months within two years after their offense and their characteristics.Between January 2010 and December 2012, data were collected from 1316 consecutive drivers who were referred to an expertise in a legal medicine Swiss institute to recover their driver’s license after driving under the influence of alcohol. 153 offenders were included in the analysis after excluding patients under the influence of other recreational drugs and patients unfit to drive for other medical reasons. Heavy DUI were defined as first time drunk driving offenders with blood alcohol concentration (BAC) ≥2.50 g/kg, or second-time drunk driving offenders within five years with BAC ≥1.60 g/kg in five years, or third-time drunk driving offenders within ten years with BAC ≥0.80 g/kg. 28 subjects of 153 (18%) were considered fit to drive. The rest of the drivers (125, 82%) were considered unfit to drive (drinking problem 77, dissociation alone 48). The majority of offenders (46,4 %) had driving under the influence of alcohol 2 times in the last five years with BAC ≥ 1.60 g/Kg, 65 (42.5%) had BAC ≥ 2.5 and the rest had 3 or more drunk driving offenses. The criteria used for medical and/or psychological assessment are appropriate.