bluuebunny/crossref_metadata_2025 huggingface dataset:
Non-Destructive Testing for Winding Insulation Diagnosis Using Inter-Turn Transient Voltage Signature Analysis
Authors: Radja Nadia , Rachek M’hemed , Nait Larbi Soraya
Published: May 2018

The paper proposes a novel approach to assess the integrity of Electrical Insulation Systems (EIS) by evaluating the response of the Transient Voltage Signature Analysis (VSA) to voltage source inverters correlated with changes in the Insulation Capacitance (IC). The involved model structures are derived from the in-situ estimation of high-frequency electromagnetic RLMC lumped network parameters. Different physical phenomena such as inductive and capacitive effects, as well as skin and proximity effects are combined. To account for these phenomena, we use an approach based on equivalent multi-transmission line electric circuits with distributed parameters (R: resistances, L, M: self and mutual inductances, and C: capacitances) which are frequency-dependent. Using the finite element method, firstly the turn-to-ground and turn-to-turn capacitance parameters are performed by solving an electrostatic model with a floating electric potential approach, and secondly, the resistance and self/mutual inductances are computed from the strongly coupled magneto-harmonic and total current density equations, including the conduction and displacement eddy current densities. The sensitivity of the capacitances is measured according to insulation thickness, and the dielectric properties are adopted to test the degradation order scenarios of the EIS and comparing their time and frequency domains of transient voltage waveform behavior with respect to healthy assessed insulation systems.
Pressurized Liquid Extraction (PLE) as an Innovative Green Technology for the Effective Enrichment of Galician Algae Extracts with High Quality Fatty Acids and Antimicrobial and Antioxidant Properties
Authors: Otero Paz , Quintana Somaris E. , Reglero Guillermo , Fornari Tiziana , García-Risco Mónica R.
Published: May 2018

Marine organisms are potentially prolific sources of high qualify fatty acids that represent useful leads in the development of new nutraceutical agents. In this work, we investigated the lipid composition of six algae species from the Northwest of Spain (Ulva intestinalis, Ulva lactuca, Fucus vesiculosus, Dictyota dichotoma, Cystoseira baccata and Himanthalia elongata) and compared the antioxidant and antibacterial activity of ethanolic extracts obtained by pressurized liquid extraction (PLE). Furthermore, Fucus vesiculosus (F. vesiculosus) PLE using five solvents of different polarities (hexane, ethyl acetate, acetone, ethanol and ethanol:water 50:50) at three temperatures (80 °C, 120 °C and 160 °C) was investigated. F. vesiculosus ethanolic PLE extract presents considerably higher capacity of inhibiting 50% of DPPH (1,1-diphenyl-2-picryl hydrazyl) (IC50 = 7.17 μg/mL) in comparison with the rest of macroalgae studied. Moreover, the potential antimicrobial activity tested on E. coli and S. aureus shows that F. vesiculosus extract produced the best inhibition (IC50 was 2.24 mg/mL (E. coli) and 1.27 mg/mL (S. aureus)). Furthermore, regarding the different solvents and temperatures used to investigate F. vesiculosus PLE, results showed that this technique using ethyl acetate is a selective method to enrich long chain fatty acids (oleic acid, arachidonic acid and eicosapentaenoic acid) with ω-6/ω-3 ratios close to 2.7.
Development of a Fully Flexible Sheet-Type Tactile Display Based on Electrovibration Stimulus
Authors: Ishizuka Hiroki , Hatada Ryuhei , Cortes Carlos , Miki Norihisa
Published: May 2018

Tactile displays have been extensively studied for several decades. However, owing to their bulkiness and stiffness, it has been difficult to integrate these displays with information devices to enable tactile communication between the devices and their users. This paper proposes a novel sheet-type electrovibration tactile display that consists of poly(3,4-ethylenedioxythiophene) polystyrene sulfonate conductive layers and an insulation layer of polydimethylsiloxane. The tactile display is sufficiently thin and flexible for attaching onto various surfaces. In this study, the tactile display was micro-fabricated and characterized through experiments. The experimental results indicated that the tactile display exhibited good durability under bending and that it could present various tactile sensations depending on the type of voltage waveform. In addition, the effect of using a combination of electrovibration and thermal stimuli was also demonstrated. The sheet-type display was attached onto a Peltier element; the thinness of the structure enabled the display to conform to the element and ensure good heat transfer. In the experiment, subjects were asked to scan the display with their fingertips. The results showed that multiple tactile stimuli were also successfully perceived by the subjects.
Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae
Authors: Drejer Eivind B. , Hakvåg Sigrid , Irla Marta , Brautaset Trygve
Published: May 2018

Although Escherichia coli and Bacillus subtilis are the most prominent bacterial hosts for recombinant protein production by far, additional species are being explored as alternatives for production of difficult-to-express proteins. In particular, for thermostable proteins, there is a need for hosts able to properly synthesize, fold, and excrete these in high yields, and thermophilic Bacillaceae represent one potentially interesting group of microorganisms for such purposes. A number of thermophilic Bacillaceae including B. methanolicus, B. coagulans, B. smithii, B. licheniformis, Geobacillus thermoglucosidasius, G. kaustophilus, and G. stearothermophilus are investigated concerning physiology, genomics, genetic tools, and technologies, altogether paving the way for their utilization as hosts for recombinant production of thermostable and other difficult-to-express proteins. Moreover, recent successful deployments of CRISPR/Cas9 in several of these species have accelerated the progress in their metabolic engineering, which should increase their attractiveness for future industrial-scale production of proteins. This review describes the biology of thermophilic Bacillaceae and in particular focuses on genetic tools and methods enabling use of these organisms as hosts for recombinant protein production.
Synthesis of Di-(2-ethylhexyl) Phosphoric Acid (D2EHPA)-Tributyl Phosphate (TBP) Impregnated Resin and Application in Adsorption of Vanadium(IV)
Authors: Zheng Ruwei , Bao Shenxu , Zhang Yimin , Chen Bo
Published: May 2018

In order to improve the adsorption capability of solvent-impregnated resins (SIRs) for vanadium(IV) (V(IV)), the dual extractant (D2EHPA (Di-(2-ethylhexyl) phosphoric acid) and TBP (Tributyl phosphate)) impregnated resins (D-TIRs) were prepared by impregnating AmberliteTM XAD-16HP macroporous resins with the mixed extractant that is composed by different molar ratios of D2EHPA to TBP. The effects of the ratio of D2EHPA to TBP on the performance of D-TIRs were investigated. The results show that the impregnation ratio of the D-TIRs decreases gradually with the increasing proportion of TBP in the mixed extractant. The sole-TBP impregnated resins (TIRs) have no adsorption capability for V(IV), indicating that the adsorption of V(IV) is attributed to D2EHPA. The adsorption capacity of D-TIRs for V(IV) attained the maximum when the ratio of D2EHPA to TBP is 7:3 at pH 1.8, and it can be improved by increasing the extractants concentration during the impregnation process. Adsorption isotherm indicates that the addition of TBP can increase the adsorption capacity of D-TIRs for V(IV) from 24.65 to 29.75 mg/g after 16 h reaction. Adsorption kinetics verifies that the addition of TBP can largely accelerate the adsorption equilibrium of V(IV) onto the D-TIRs and V(IV). Electrospray ionization (ESI) mass spectra and Fourier transform infrared spectra (FT-IR) analysis indicates that the addition of TBP to D2EHPA can make some dimeric D2EHPA change to monomers by breaking the hydrogen bonds of D2EHPA-dimers, leading to the result that the pseudo-second order kinetic for the adsorption of V(IV) onto the D2EHPA impregnated resins (DIRs) converts to the pseudo-first order kinetic for that onto the D-TIRs. Also, D-TIRs have better separation capability of V(IV) from Fe(II) and Al(III) in the vanadium leaching solution than DIRs.
Interfacial Precipitation of Phosphate on Hematite and Goethite
Authors: Wang Lijun , Putnis Christine V. , Hövelmann Jörn , Putnis Andrew
Published: May 2018

Adsorption and subsequent precipitation of dissolved phosphates on iron oxides, such as hematite and goethite, is of considerable importance in predicting the bioavailability of phosphates. We used in situ atomic force microscopy (AFM) to image the kinetic processes of phosphate-bearing solutions interacting with hematite or goethite surfaces. The nucleation of nanoparticles (1.0–4.0 nm in height) of iron phosphate (Fe(III)-P) phases, possibly an amorphous phase at the initial stages, was observed during the dissolution of both hematite and goethite at the earliest crystallization stages. This was followed by a subsequent aggregation stage where larger particles and layered precipitates are formed under different pH values, ionic strengths, and organic additives. Kinetic analysis of the surface nucleation of Fe-P phases in 50 mM NH4H2PO4 at pH 4.5 showed the nucleation rate was greater on goethite than hematite. Enhanced goethite and hematite dissolution in the presence of 10 mM AlCl3 resulted in a rapid increase in Fe-P nucleation rates. A low concentration of citrate promoted the nucleation, whereas nucleation was inhibited at higher concentrations of citrate. By modeling using PHREEQC, calculated saturation indices (SI) showed that the three Fe(III)-P phases of cacoxenite, tinticite, and strengite may be supersaturated in the reacted solutions. Cacoxenite is predicted to be more thermodynamically favorable in all the phosphate solutions if equilibrium is reached with respect to hematite or goethite, although possibly only amorphous precipitates were observed at the earliest stages. These direct observations at the nanoscale may improve our understanding of phosphate immobilization in iron oxide-rich acid soils.
Innovative Formulation Combining Al, Zr and Si Precursors to Obtain Anticorrosion Hybrid Sol-Gel Coating
Authors: Genet Clément , Menu Marie-Joëlle , Gavard Olivier , Ansart Florence , Gressier Marie , Montpellaz Robin
Published: May 2018

The aim of our study is to improve the aluminium alloy corrosion resistance with Organic-Inorganic Hybrid (OIH) sol-gel coating. Coatings are obtained from unusual formulation with precursors mixing: glycidoxypropyltrimethoxysilane (GPTMS), zirconium (IV) propoxide (TPOZ) and aluminium tri-sec-butoxide (ASB). This formulation was characterized and compared with sol formulations GPTMS/TPOZ and GPTMS/ASB. In each formulation, a corrosion inhibitor, cerium (III) nitrate hexahydrate, is employed to improve the corrosion performance. Coatings obtained from sol based on GPTMS/TPOZ/ASB have good anti-corrosion performances with Natural Salt Spray (NSS) resistance of 500 h for a thickness lower than 4 µm. Contact angle measurement showed a coating hydrophobic behaviour. To understand these performances, nuclear magnetic resonance (NMR) analyses were performed, results make sol-gel coating condensation evident and are in very good agreement with previous results.
Fingerprint-Based Machine Learning Approach to Identify Potent and Selective 5-HT2BR Ligands
Authors: Rataj Krzysztof , Kelemen Ádám Andor , Brea José , Loza María Isabel , Bojarski Andrzej J. , Keserű György Miklós
Published: May 2018

The identification of subtype-selective GPCR (G-protein coupled receptor) ligands is a challenging task. In this study, we developed a computational protocol to find compounds with 5-HT2BR versus 5-HT1BR selectivity. Our approach employs the hierarchical combination of machine learning methods, docking, and multiple scoring methods. First, we applied machine learning tools to filter a large database of druglike compounds by the new Neighbouring Substructures Fingerprint (NSFP). This two-dimensional fingerprint contains information on the connectivity of the substructural features of a compound. Preselected subsets of the database were then subjected to docking calculations. The main indicators of compounds’ selectivity were their different interactions with the secondary binding pockets of both target proteins, while binding modes within the orthosteric binding pocket were preserved. The combined methodology of ligand-based and structure-based methods was validated prospectively, resulting in the identification of hits with nanomolar affinity and ten-fold to ten thousand-fold selectivities.
Structural Characterization of Lithium and Sodium Bulky Bis(silyl)amide Complexes
Authors: Nicholas Hannah M. , Goodwin Conrad A. P. , Kragskow Jon G. C. , Lockyer Selena J. , Mills David P.
Published: May 2018

Alkali metal amides are vital reagents in synthetic chemistry and the bis(silyl)amide {N(SiMe3)2} (N′′) is one of the most widely-utilized examples. Given that N′′ has provided landmark complexes, we have investigated synthetic routes to lithium and sodium bis(silyl)amides with increased steric bulk to analyse the effects of R-group substitution on structural features. To perform this study, the bulky bis(silyl)amines {HN(SitBuMe2)(SiMe3)}, {HN(SiiPr3)(SiMe3)}, {HN(SitBuMe2)2}, {HN(SiiPr3)(SitBuMe2)} and {HN(SiiPr3)2} (1) were prepared by literature procedures as colourless oils; on one occasion crystals of 1 were obtained. These were treated separately with nBuLi to afford the respective lithium bis(silyl)amides [Li{μ-N(SitBuMe2)(SiMe3)}]2 (2), [Li{μ-N(SiiPr3)(SiMe3)}]2 (3), [Li{N(SitBuMe2)2}{μ-N(SitBuMe2)2}Li(THF)] (4), [Li{N(SiiPr3)(SitBuMe2)}(DME)] (6) and [Li{N(SiiPr3)2}(THF)] (7) following workup and recrystallization. On one occasion during the synthesis of 4 several crystals of the ‘ate’ complex [Li2{μ-N(SitBuMe2)2}(μ-nBu)]2 (5) formed and a trace amount of [Li{N(SiiPr3)2}(THF)2] (8) was identified during the recrystallization of 7. The reaction of {HN(SitBuMe2)2} with NaH in the presence of 2 mol % of NaOtBu gave crystals of [Na{μ-N(SitBuMe2)2}(THF)]2 (9-THF), whilst [Na{N(SiiPr3)2}(C7H8)] (10) was prepared by deprotonation of 1 with nBuNa. The solid-state structures of 1–10 were determined by single crystal X-ray crystallography, whilst 2–4, 7, 9 and 10 were additionally characterized by NMR and FTIR spectroscopy and elemental microanalysis.
Profiling of Phenolic Compounds and Antioxidant Activity of 12 Cruciferous Vegetables
Authors: Li Zhifeng , Lee Hui Wen , Liang Xu , Liang Dong , Wang Qi , Huang Dejian , Ong Choon Nam
Published: May 2018

The phenolic profiles of 12 cruciferous vegetables (pakchoi, choysum, Chinese cabbage, kailan, Brussels sprout, cabbage, cauliflower, broccoli, rocket salad, red cherry radish, daikon radish, and watercress) were studied with UHPLC-MS/MS. Antioxidant activity and total phenolic content (TPC) were also evaluated. A total of 74 phenolic compounds were identified, including 16 hydroxycinnamic acids and derivatives, and 58 flavonoids and derivatives. The main flavonoids identified were glycosylated quercetin, kaempferol and isorhamnetin, and the main hydroxycinnamic acids were ferulic, sinapic, caffeic and p-coumaric acids. Principal component analysis (PCA) revealed that the distribution of phenolic compounds in different genera of cruciferous vegetables was in accordance with their conventional taxonomy. The DPPH, ORAC and TPC values ranged from 1.11 to 9.54 µmoles Trolox equivalent/g FW, 5.34 to 32.92 µmoles Trolox equivalent/g FW, and 0.16 to 1.93 mg gallic acid equivalent/g FW respectively. Spearman’s correlation showed significant (p < 0.05) positive correlations between TPC, flavonoids and antioxidant activity.
Pterostilbene and 4′-Methoxyresveratrol Inhibited Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages
Authors: Yao Yun , Liu Kehai , Zhao Yueliang , Hu Xiaoqian , Wang Mingfu
Published: May 2018

Pterostilbene (Pte) and 4′-Methoxyresveratrol (4MR) are methylated derivatives of resveratrol. We investigated the anti-inflammatory effect of Pte and 4MR in lipopolysaccharide (LPS)-stimulated RAW264.7 murine macrophages. Both Pte and 4MR significantly reduced LPS-induced nitric oxide release by inhibiting the inducible nitric oxide synthase mRNA expression. Moreover, both of them inhibited LPS-induced mRNA expression of inflammatory cytokines including monocyte chemoattractant protein (MCP)-1, interleukin (IL)-6 and IL-1β, and tumor necrosis factor α (TNF-α), and attenuated LPS-induced nuclear factor-κB (NF-κB) activation by decreasing p65 phosphorylation. In addition, 4MR but not Pte inhibited LPS-induced the activator protein (AP)-1 pathway in RAW 264.7 macrophages. Further study suggested that Pte had an inhibitory effect on extracellular regulated protein kinases (ERK) and p38 activation, but not on c-Jun N-terminal kinase (JNK), while 4MR had an inhibitory effect on JNK and p38 activation, but not on ERK. Taken together, our data suggested that Pte induced anti-inflammatory activity by blocking mitogen-activated protein kinase (MAPK) and NF-κB signaling pathways, while 4MR showed anti-inflammatory activity through suppression of MAPK, AP-1, and NF-κB signaling pathways in LPS-treated RAW 264.7 macrophages.
Sound Descriptions of Haptic Experiences of Art Work by Deafblind Cochlear Implant Users
Authors: Lahtinen Riitta , Groth Camilla , Palmer Russ
Published: May 2018

Deafblind persons’ perception and experiences are based on their residual auditive and visual senses, and touch. Their haptic exploration, through movements and orientation towards objects give blind persons direct, independent experience. Few studies explore the aesthetic experiences and appreciation of artefacts of deafblind people using cochlear implant (CI) technology, and how they interpret and express their perceived aesthetic experience through another sensory modality. While speech recognition is studied extensively in this area, the aspect of auditive descriptions made by CI users are a less-studied domain. This present research intervention describes and analyses five different deafblind people sharing their interpretation of five statues vocally, using sounds and written descriptions based on their haptic explorations. The participants found new and multimodal ways of expressing their experiences, as well as re-experiencing them through technological aids. We also found that the CI users modify technology to better suit their personal needs. We conclude that CI technology in combination with self-made sound descriptions enhance memorization of haptic art experiences that can be re-called by the recording of the sound descriptions. This research expands the idea of auditive descriptions, and encourages user-produced descriptions as artistic supports to traditional linguistic, audio descriptions. These can be used to create personal auditive–haptic memory collections similar to how sighted create photo albums.
Effect of Phenolic Compounds on the Synthesis of Gold Nanoparticles and its Catalytic Activity in the Reduction of Nitro Compounds
Authors: Alegria Elisabete , Ribeiro Ana , Mendes Marta , Ferraria Ana , Do Rego Ana , Pombeiro Armando
Published: May 2018

Gold nanoparticles (AuNPs) were prepared using an eco-friendly approach in a single step by reduction of HAuCl4 with polyphenols from tea extracts, which act as both reducing and capping agents. The obtained AuNPs were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), ultraviolet–visible spectroscopy (UV–vis), and X-ray photoelectron spectroscopy (XPS). They act as highly efficient catalysts in the reduction of various aromatic nitro compounds in aqueous solution. The effects of a variety of factors (e.g., reaction time, type and amount of reducing agent, shape, size, or amount of AuNPs) were studied towards the optimization of the processes. The total polyphenol content (TPC) was determined before and after the catalytic reaction and the results are discussed in terms of the tea extract percentage, the size of the AuNPs, and their catalytic activity. The reusability of the AuNP catalyst in the reduction of 4-nitrophenol was also tested. The reactions follow pseudo first-order kinetics.
Dietary Neurotransmitters: A Narrative Review on Current Knowledge
Authors: Briguglio Matteo , Dell’Osso Bernardo , Panzica Giancarlo , Malgaroli Antonio , Banfi Giuseppe , Zanaboni Dina Carlotta , Galentino Roberta , Porta Mauro
Published: May 2018

Foods are natural sources of substances that may exert crucial effects on the nervous system in humans. Some of these substances are the neurotransmitters (NTs) acetylcholine (ACh), the modified amino acids glutamate and γ-aminobutyric acid (GABA), and the biogenic amines dopamine, serotonin (5-HT), and histamine. In neuropsychiatry, progressive integration of dietary approaches in clinical routine made it necessary to discern the more about some of these dietary NTs. Relevant books and literature from PubMed and Scopus databases were searched for data on food sources of Ach, glutamate, GABA, dopamine, 5-HT, and histamine. Different animal foods, fruits, edible plants, roots, and botanicals were reported to contain NTs. These substances can either be naturally present, as part of essential metabolic processes and ecological interactions, or derive from controlled/uncontrolled food technology processes. Ripening time, methods of preservation and cooking, and microbial activity further contributes to NTs. Moreover, gut microbiota are considerable sources of NTs. However, the significance of dietary NTs intake needs to be further investigated as there are no significant data on their bioavailability, neuronal/non neuronal effects, or clinical implications. Evidence-based interventions studies should be encouraged.
Protective Effect of Highly Polymeric A-Type Proanthocyanidins from Seed Shells of Japanese Horse Chestnut (Aesculus turbinata BLUME) against Light-Induced Oxidative Damage in Rat Retina
Authors: Ishihara Tomoe , Kaidzu Sachiko , Kimura Hideto , Koyama Yasurou , Matsuoka Yotaro , Ohira Akihiro
Published: May 2018

Retinal tissue is exposed to oxidative stress caused by visible light. Light-damaged rat used in age-related macular degeneration (AMD) studies clarified that antioxidants decrease retinal light damage. Albino rats were exposed to 5000 Lux light for 12 h with oral administration of the polyphenolic compounds fraction (PF) from the seed shells of Japanese horse chestnut (30 mg/kg, 100 mg/kg, and 300 mg/kg body weight: BW). To evaluate the protective effects against light damage, electroretinograms (ERGs), the outer nuclear layer (ONL) thickness, the antioxidant activity of plasma, oxidized retinal lipids, and the detection of apoptosis were examined. To reveal their active compounds, PF were separated into an A-type proanthocyanidin (PAF) and a flavonol O-glycosides fraction. The protective effects of these fractions against light damage were compared by measuring the thickness of the ERGs and ONL. Compared with the negative control, the PF group (100 mg/kg and 300 mg/kg BW) significantly suppressed the decrease of the ERG amplitudes and ONL thickness. PF (300 mg/kg BW) induced the elevation of in vivo antioxidant activity, and the suppression of retinal lipid oxidation. PF administration also suppressed apoptotic cell death. The protective effects against light damage were attributable to the antioxidant activity of PAF. The light-induced damage of retinas was protected by oral administration of PF and PAF. Taken together, these compounds are potentially useful for the prevention of the disease caused by light exposure. Highlights: The protective effects of retinal damage by light exposure were evaluated using polyphenolic compounds from the seed shells of Japanese horse chestnut (Aesculus turbinata BLUME) as an antioxidant. Decreases in the electroretinographic amplitude and outer nuclear layer thickness were suppressed by the polyphenolic compounds of the seed shells. Polyphenolic compounds from the seed shells of Japanese horse chestnut inhibited the oxidation of retinal lipids. Highly polymeric A-type proanthocyanidin from the seed shells protected the rat retina from light exposure damage by inhibiting oxidative stress and apoptotic mechanisms.
Developing an Integrated Remote Sensing Based Biodiversity Index for Predicting Animal Species Richness
Authors: Wu Jinhui , Liang Shunlin
Published: May 2018

Many remote sensing metrics have been applied in large-scale animal species monitoring and conservation. However, the capabilities of these metrics have not been well compared and assessed. In this study, we investigated the correlation of 21 remote sensing metrics in three categories with the global species richness of three different animal classes using several statistical methods. As a result, we developed a new index by integrating several highly correlated metrics. Of the 21 remote sensing metrics analyzed, evapotranspiration (ET) had the greatest impact on species richness on a global scale (explained variance: 52%). The metrics with a high explained variance on the global scale were mainly in the energy/productivity category. The metrics in the texture category exhibited higher correlation with species richness at regional scales. We found that radiance and temperature had a larger impact on the distribution of bird richness, compared to their impacts on the distributions of both amphibians and mammals. Three machine learning models (i.e., support vector machine, random forests, and neural networks) were evaluated for metric integration, and the random forest model showed the best performance. Our newly developed index exhibited a 0.7 explained variance for the three animal classes’ species richness on a global scale, with an explained variance that was 20% higher than any of the univariate metrics.
An Emotion Aware Task Automation Architecture Based on Semantic Technologies for Smart Offices
Authors: Muñoz Sergio , Araque Oscar , Sánchez-Rada J. Fernando , Iglesias Carlos A.
Published: May 2018

The evolution of the Internet of Things leads to new opportunities for the contemporary notion of smart offices, where employees can benefit from automation to maximize their productivity and performance. However, although extensive research has been dedicated to analyze the impact of workers’ emotions on their job performance, there is still a lack of pervasive environments that take into account emotional behaviour. In addition, integrating new components in smart environments is not straightforward. To face these challenges, this article proposes an architecture for emotion aware automation platforms based on semantic event-driven rules to automate the adaptation of the workplace to the employee’s needs. The main contributions of this paper are: (i) the design of an emotion aware automation platform architecture for smart offices; (ii) the semantic modelling of the system; and (iii) the implementation and evaluation of the proposed architecture in a real scenario.
High-Speed Lateral Flow Strategy for a Fast Biosensing with an Improved Selectivity and Binding Affinity
Authors: Cho Dong Guk , Yoo Haneul , Lee Haein , Choi Yeol Kyo , Lee Minju , Ahn Dong June , Hong Seunghun
Published: May 2018

We report a high-speed lateral flow strategy for a fast biosensing with an improved selectivity and binding affinity even under harsh conditions. In this strategy, biosensors were fixed at a location away from the center of a round shape disk, and the disk was rotated to create the lateral flow of a target solution on the biosensors during the sensing measurements. Experimental results using the strategy showed high reaction speeds, high binding affinity, and low nonspecific adsorptions of target molecules to biosensors. Furthermore, binding affinity between target molecules and sensing molecules was enhanced even in harsh conditions such as low pH and low ionic strength conditions. These results show that the strategy can improve the performance of conventional biosensors by generating high-speed lateral flows on a biosensor surface. Therefore, our strategy can be utilized as a simple but powerful tool for versatile bio and medical applications.
Agent-Based Intelligent Interface for Wheelchair Movement Control
Authors: Barriuso Alberto L. , Pérez-Marcos Javier , Jiménez-Bravo Diego M. , Villarrubia González Gabriel , De Paz Juan F.
Published: May 2018

People who suffer from any kind of motor difficulty face serious complications to autonomously move in their daily lives. However, a growing number research projects which propose different powered wheelchairs control systems are arising. Despite of the interest of the research community in the area, there is no platform that allows an easy integration of various control methods that make use of heterogeneous sensors and computationally demanding algorithms. In this work, an architecture based on virtual organizations of agents is proposed that makes use of a flexible and scalable communication protocol that allows the deployment of embedded agents in computationally limited devices. In order to validate the proper functioning of the proposed system, it has been integrated into a conventional wheelchair and a set of alternative control interfaces have been developed and deployed, including a portable electroencephalography system, a voice interface or as specifically designed smartphone application. A set of tests were conducted to test both the platform adequacy and the accuracy and ease of use of the proposed control systems yielding positive results that can be useful in further wheelchair interfaces design and implementation.
Effect of Massoia (Massoia aromatica Becc.) Bark on the Phagocytic Activity of Wistar Rat Macrophages
Authors: Hertiani Triana , Yuswanto Agustinus , Utami Tunjung Pratiwi Sylvia , Muthma’innah Mashar Harlyanti
Published: May 2018

The essential oil of Massoia (Massoia aromatica Becc., Lauraceae) bark is a potential immunomodulator in vitro. This study evaluated the potential immunomodulatory effects of Massoia bark infusion on the nonspecific immune response (phagocytosis) of Wistar rats. For the in vitro assay, macrophages were treated with the freeze-dried infusion at the concentrations of 2.5, 5, 10, 20, or 40 µg/mL media. For the in vivo assay, two-month-old male Wistar rats were divided into five groups. The baseline group received distilled water at the dose of 1 mL/100 g body weight (BW), with the herbal product containing Phyllanthus niruri extract that was administered as the positive control at the dose of 0.54 mL/rat. The treatment groups received the infusion at a dose of 100, 300, or 500 mg/100 g BW. Treatments were given orally every day for 14 days. The ability of macrophage cells to phagocyte latex was determined as phagocytic index (PI), and it was observed under microscopy with 300 macrophages. The in vitro study revealed that the phagocytic activity of the infusion-treated macrophages significantly increased in comparison with that of the control macrophages in a concentration-dependent manner. Among all of the treatment concentrations, the concentration of 40 µg/mL provided the highest activity with a PI value of 70.51 ± 1.11%. The results of the in vivo assay confirmed those of the in vitro assay. The results of the present study indicate that Massoia bark can increase the phagocytic activity of rat macrophage cells.
Some Influences of Underground Coal Gasification on the Environment
Authors: Kostúr Karol , Laciak Marek , Durdan Milan
Published: May 2018

Increasing energy costs and energy demand have renewed global interest in clean coal technologies. Underground Coal Gasification (UCG) is an industrial process that converts coal into product gas. UCG is a promising technology with a lot of health, safety and environmental advantages over conventional mining techniques. UCG carries risks to human health, agriculture and the environment. This article briefly analyzes the advantages and negative environmental impacts of UCG. It describes experimental objects, mathematical models as tools for simulation cases and it used coal from UCG experiments in Cigel, Barbara and Wieczorek mines to analyze the environmental impacts of UCG. The gasification converts the carbon in the coal to syngas and heat. We carried out a numerical simulation of the two-dimensional unstable heat conduction in the coal and overburden, with the aim of judging the influence of this heat source on the surroundings, including the surface. The results show that the temperature in the surrounding rock first increases and then decreases with time, the peak of the temperature curve decreases gradually, and its position moves inside the surrounding rock from the ignition point. A small amount of potentially dangerous syngas leaks from the UCG cavity and channels into vulnerable areas depending on working pressures. The danger of explosion and poisoning in vulnerable zones was evaluated by the simulation model. The results show that the danger is real but by monitoring and controlling the air in the vulnerable area it is possible to reduce this risk.
A Comparison of Vacancy Dynamics between Growing and Shrinking Cities Using the Land Transformation Model
Authors: Lee Jaekyung , Newman Galen , Park Yunmi
Published: May 2018

Every city seeks opportunities to spur economic developments and, depending on its type, vacant land can be seen as a potential threat or an opportunity to achieve these developments. Although vacant land exists in all cities, the causes and effects of changes in vacant land can differ. Growing cities may have more vacant land than shrinking cities because of large scale annexation. Meanwhile, depopulation and economic downturn may increase the total amount of vacant and abandoned properties. Despite various causes of increase and decrease of vacant land, the ability to predict future vacancy patterns—where future vacant parcels may occur—could be a critical test to set up appropriate development strategies and land use policies, especially in shrinking cities, to manage urban decline and regeneration efforts more wisely. This study compares current and future vacancy patterns of a growing city (Fort Worth, TX, USA) and a shrinking city (Chicago, IL, USA), by employing the Land Transformation Model (LTM) to predict for future vacant lands. This research predicts and produces possible vacancy pattern scenarios by 2020 and deciphers the ranking of determinants of vacant land in each city type. The outcomes of this study indicate that the LTM can be useful for simulating vacancy patterns and the causes of vacancy vary in both growing and shrinking cities. Socio-economic factors such as unemployment rate and household income are powerful determinants of vacancy in a growing city, while physical and transportation-related conditions such as proximity to highways, vehicle accessibility, or building conditions show a stronger influence on increasing vacant land in a shrinking city.
Agricultural GMOs—What We Know and Where Scientists Disagree
Authors: Zilberman David , Holland Tim G. , Trilnick Itai
Published: May 2018

Population growth, climate change, and increasing human impact on land and aquatic systems all pose significant challenges for current agricultural practices. Genetic engineering is a tool to speed up breeding for new varieties, which can help farmers and agricultural systems adapt to rapidly changing physical growing conditions, technology, and global markets. We review the current scientific literature and present the potential of genetically modified organisms (GMOs) from the perspectives of various stakeholders. GMOs increase yields, lower costs, and reduce the land and environmental footprint of agriculture. The benefits of this technology are shared among innovators, farmers, and consumers. Developing countries and poor farmers gain substantially from GMOs. Agricultural biotechnology is diverse, with many applications having different potential impacts. Its regulation needs to balance benefits and risks for each application. Excessive precaution prevents significant benefits. Increasing access to the technology and avoidance of excessive regulation will allow it to reach its potential.
Research on a Microgrid Subsidy Strategy Based on Operational Efficiency of the Industry Chain
Authors: Long Yong , Pan Chengrong , Wang Yu
Published: May 2018

Government subsidy is a powerful tool to motivate the development of a new energy industry. At the early stage of microgrid development, for the sake of the cost and benefit issue, it is necessary for the government to subsidize so as to support and promote the development of microgrids. However, a big challenge in practice is how to optimize the operational efficiency of the microgrid industry chain with varying targets and methods of subsidy. In order to explore this problem, we construct a subsidy model based on the microgrid industry chain, involving government, investor, operator, equipment supplier, and user. Through calculation and solution of this model, we obtain price and return indicators of each microgrid industry chain participant when the subsidy target differs. Based on that, we contrast and compare the optimal subsidy strategy and influencing factors when operational efficiency indicators vary. Finally, we validate and analyze this model with numerical analysis and discuss the impact of development stage, technological level, and change in subsidy amount on the operational efficiency of the microgrid industry chain and on the returns of each participant. This result is of great significance to subsidy practice for microgrids and the development of microgrids.
Correction: Huang, H., et al. The Total-Factor Energy Efficiency of Regions in China: Based on Three-Stage SBM Model. Sustainability 2017, 9, 1664
Authors: Huang Haifeng , Wang Tao
Published: May 2018

The authors did not realize the errors made in the affiliations and references in the proofreading phase. [...]
Eco-Labeling and Retailer Pricing Strategies: The U.K. Haddock Market
Authors: Zhang Dengjun , Sogn-Grundvåg Geir , Asche Frank , Young James A.
Published: May 2018

In attempts to differentiate their store imagery, grocery retailers frequently introduce new products, which are often rich in extrinsic attributes such as claims regarding healthiness and environmental sustainability. This paper explores retailers’ pricing strategies for product attributes of haddock in the United Kingdom. The results show that retailers’ pricing strategies vary, in particular for extrinsic product attributes such as eco-labels and country-of-origin. The high price premium generated from the most advocated eco-labels and an emphasis upon promotion strategies appear to play a role in the success of high-end retailers, and may have implications for any heightened competitive responses by larger retail chains in the future.
Measuring the Sustainability of Construction Projects throughout Their Lifecycle: A Taiwan Lesson
Authors: Yu Wen-der , Cheng Shao-tsai , Ho Wei-cheng , Chang Yu-hao
Published: May 2018

Researchers have proposed many industrial or national sustainability evaluation indicator systems during the past decade, although there has not yet been a project-level sustainability evaluation system for the evaluation and execution monitoring of the sustainability status for a construction project. Without such an evaluation system, it will be difficult for the planners to plan the sustainable project objectives, for the contractors to select the sustainable execution alternatives, and for the facility managers to operate sustainable constructed facilities. To meet the abovementioned requirements, this paper presents an effort conducted in Taiwan to propose a Construction Project Sustainability Assessing System (CPSAS) considering three pillars of sustainability: environmental, social, and economic, based on the theoretical backgrounds from the literature and former successful sustainable projects. The proposed CPSAS comprises four levels: Level 1, 3 main pillars; Level 2, 8 categories; Level 3, 19 sub-categories; and Level 4, 31 indicators. Different selections of indicators for application in different project phases are suggested according to the prioritization via questionnaire surveys. A procedure for sustainable project management with the proposed CPSAS is suggested to the project management team. Finally, three green building projects and two civil infrastructure construction projects of Taiwan were tested to demonstrate the feasibility of the proposed CPSAS. It is concluded that the proposed CPSAS is useful for construction stakeholders to achieve sustainability more effectively during the execution of a construction project.
Uncovering Productivity Gains of Digital and Green Servitization: Implications from the Automotive Industry
Authors: Opazo-Basáez Marco , Vendrell-Herrero Ferran , Bustinza Oscar F.
Published: May 2018

The growing industrial concern about sustainability challenges has driven vehicle and auto parts manufacturers to adopt service capabilities as a way to maintain competitiveness in compliance with environmental regulations. As a result, automakers have progressively integrated digital and green service initiatives to support operations and address environmental issues effectively. The present study examined the effect of digital and green servitization on the firm’s productivity. To test their effect quantitatively, this study used the ORBIS database to construct a multi-country sample containing 228 companies in the automotive industry. Our findings indicate that implementation of digital and green servitization is positively associated with higher productivity outcomes once the two forms of servitization coexist and operate jointly. Moreover, the results of the study underscore the importance of establishing a successional pathway of implementation priorities. Our evidence suggests that firms willing to offer green services should consider offering digital services first, as this is the only way to obtain productivity gains from green servitization.
New Holographic Dark Energy Model in Brans-Dicke Theory
Authors: Sharif M. , Asif Ali Shah Syed , Bamba Kazuharu
Published: May 2018

We study the cosmic evolution of the Bianchi type I universe by using new holographic dark energy model in the context of the Brans-Dicke theory for both non-interacting and interacting cases between dark energy and dark matter. We evaluate the equation of state for dark energy ω D and draw the ω D − ω ˙ D plane, where the dot denotes the time derivative. It is found that a stage in which the cosmic expansion is accelerating can be realized in both cases. In addition, we investigate the stability of the model by analyzing the sound speed. As a result, it is demonstrated that for both cases, the behavior of the sound speed becomes unstable. Furthermore, with the Om-diagnostic tool, it is shown that the quintessence region of the universe can exist.
Purification and Characterization of Recombinant Botulinum Neurotoxin Serotype FA, Also Known as Serotype H
Authors: Hackett Gavin , Moore Kevin , Burgin David , Hornby Fraser , Gray Bryony , Elliott Mark , Mir Imran , Beard Matthew
Published: May 2018

We have purified and characterized recombinant botulinum neurotoxin serotype FA (BoNT/FA). This protein has also been named as a new serotype (serotype H), but the classification has been controversial. A lack of well-characterized, highly pure material has been a roadblock to study. Here we report purification and characterization of enzymatically active, and of inactive nontoxic, recombinant forms of BoNT/FA as tractable alternatives to purifying this neurotoxin from native Clostridium botulinum. BoNT/FA cleaves the same intracellular target proteins as BoNT/F1 and other F serotype BoNTs; the intracellular targets are vesicle associated membrane proteins (VAMP) 1, 2 and 3. BoNT/FA cleaves the same site in VAMP-2 as BoNT/F5, which is different from the cleavage site of other F serotype BoNTs. BoNT/FA has slower enzyme kinetics than BoNT/F1 in a cell-free protease assay and is less potent at inhibiting ex vivo nerve-stimulated skeletal muscle contraction. In contrast, BoNT/FA is more potent at inhibiting neurotransmitter release from cultured neurons.
Murray Valley Encephalitis Virus: An Ongoing Cause of Encephalitis in Australia’s North
Authors: Floridis John , McGuinness Sarah L. , Kurucz Nina , Burrow Jim N. , Baird Rob , Francis Josh R.
Published: May 2018

Murray Valley encephalitis virus (MVEV) is a mosquito-borne virus endemic to Australia and New Guinea. Encephalitis due to MVEV is potentially devastating, and no therapeutic interventions of proven value exist. Prevention relies largely on personal protective measures against mosquito bites. We present a case of MVEV encephalitis with a favourable outcome following intensive care management and prolonged rehabilitation, and the epidemiological features of a further 21 cases notified to the health department of Australia’s Northern Territory. As cases occur in travellers, and epidemics occur sporadically in south-eastern Australia, clinicians across Australia and further abroad should be familiar with the disease and its diagnosis and management.
Year-Round Irrigation Schedule for a Tomato–Maize Rotation System in Reservoir-Based Irrigation Schemes in Ghana
Authors: Sekyi-Annan Ephraim , Tischbein Bernhard , Diekkrüger Bernd , Khamzina Asia
Published: May 2018

Improving irrigation management in semi-arid regions of Sub-Saharan Africa is crucial to respond to increasing variability in rainfall and overcome deficits in current irrigation schemes. In small-scale and medium-scale reservoir-based irrigation schemes in the Upper East region of Ghana, we explored options for improving the traditional, dry season irrigation practices and assessed the potential for supplemental irrigation in the rainy season. The AquaCrop model was used to (i) assess current water management in the typical tomato-maize rotational system; (ii) develop an improved irrigation schedule for dry season cultivation of tomato; and (iii) determine the requirement for supplemental irrigation of maize in the rainy season under different climate scenarios. The improved irrigation schedule for dry season tomato cultivation would result in a water saving of 130–1325 mm compared to traditional irrigation practices, accompanied by approximately a 4–14% increase in tomato yield. The supplemental irrigation of maize would require 107–126 mm of water in periods of low rainfall and frequent dry spells, and 88–105 mm in periods of high rainfall and rare dry spells. Therefore, year-round irrigated crop production may be feasible, using water saved during dry season tomato cultivation for supplemental irrigation of maize in the rainy season.