bluuebunny/crossref_metadata_2025 huggingface dataset:
Uso de jardins verticais em sala de aula
Authors: Ribeiro Luciana Rocha , Scherer Minéia Johann , Rodrigues Marcelo Antonio
Published: April 2022

O uso da vegetação como estratégia bioclimática, no ambiente construído, é amplamente reconhecido pelos benefícios relacionados principalmente ao conforto térmico. Esta característica é proveniente do emprego da vegetação no meio urbano, tanto de forma isolada quanto integrada à edificação. Adicionalmente, a utilização de espécies vegetais também pode oferecer benefícios aos usuários de ambientes internos, melhorando a qualidade destes espaços. Este artigo tem como objetivo apresentar análises e resultados obtidos com a aplicação da ferramenta:  questionário na avaliação da percepção ambiental de estudantes, da 3ª série do ensino médio, na implantação de jardins verticais no ambiente de sala de aula, com foco na qualidade do ambiente interno. O questionário foi aplicado em três momentos: antes da inserção dos jardins verticais, vinte dias após implantação do jardim vertical da espécie Arachis repens (grama-amendoim) e vinte dias após a substituição do jardim vertical com a espécie grama-amendoim pela espécie Chlorophytum comosum (clorofito). Concluiu-se, por meio das análises geradas na aplicação do questionário, que, na percepção dos alunos, a inserção dos jardins verticais proporcionou melhorias na qualidade do ar e no conforto geral do ambiente de sala de aula. O jardim vertical da espécie grama-amendoim apresentou melhores resultados quanto à qualidade do ambiente interno, quando comparado às outras situações.
Análise da qualidade de vida urbana sob a perspectiva dos espaços públicos de lazer em Videira, SC
Authors: Camara Inara Pagnussat , Secco Rafaela Hubler , Fernandes Gustavo , Biasi Juliana Aparecida
Published: April 2022

Este trabalho analisa a qualidade de vida urbana na cidade de Videira, SC, através de um estudo realizado nos espaços públicos, destinados ao lazer. Primeiramente são classificados os sítios de lazer conforme as tipologias encontradas no município (parque, praça e largo) e investiga, baseado na evolução da cidade, a qualidade destes espaços, juntamente com sua infraestrutura, mobiliário urbano, estado de conservação e manutenção e a distribuição espacial relacionado a densidade populacional. Buscamos ainda, investigar em que medida os espaços de lazer desempenham função de qualidade ambiental e urbana, enquanto elementos do desenho urbano necessários as cidades contemporâneas. A qualidade de vida urbana pode ser percebida em níveis qualitativos e quantitativos, porém isto não é suficiente para quantificá-los pois precisamos compreender de que maneira estes espaços são distribuídos de maneira igualitária na malha urbana e atendem de maneira justa e democrática toda a população. Percebemos através das análises realizadas que os espaços são distribuídos de maneira desigual e necessitam de uma atenção mais holística no processo de planejamento urbano possibilitando cidades onde a distribuição territorial do espaço público de lazer é democrática, com as mesmas oportunidades de acesso à toda população.
Pengaruh Atribut Produk dan Promosi Melalui Media Sosial Instagram Terhadap Keputusan Pembelian Produk Waralaba Miltie bubble Di Banjarmasin Yang Di Mediasi Minat Beli
Authors: Febrianoor Rizki , Irwansyah Irwansyah , Rahmawati Emy
Published: April 2022

This research (thesis) aims to prove and analyze the direct effect of product attributes and social media promotions on consumer purchasing decisions and also the indirect effect of buying interest on consumer purchasing decisions of Miltie bubble Banjarmasin. The research method used is associative descriptive of the relationship between variables, data collection through surveys with a sample size of 100 buyers who have seen this Miltie bubble Instagram account, the sample selected using the Purposive Sampling technique. Questionnaires were distributed through the custodians of 4 miltiebubble booths with data returning 100 people. Data analysis using Structural Equation Model based on Partial Leas Square.The results showed that respondents' responses to product attributes directly had no significant effect on purchasing decisions. Promotion through Instagram directly has a significant effect on purchasing decisions. Through buying interest, product attributes have a significant effect on purchasing decisions and can be said to be perfect mediation. Through buying interest Promotion has a significant effect on purchasing decisions and is said to be partial mediation. The results of this study can be used by companies to choose the necessary product development strategies and promotional programs that will be selected. Keywords:  Atribut Produk, Promosi Medsos, Minat Beli
KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA MELALUI PENERAPAN MODEL AUDITORY, INTELLECTUALLY, REPETITION DI KELAS VIII SMP
Authors: Sari Wiyati Widya , Karim Karim , Amalia Rizki
Published: April 2022

Berdasarkan pengalaman peneliti selama Praktik Pengajaran di Sekolah yang dilasanakan di SMP Negeri 1 Banjarmasin, siswa sudah terbiasa mengerjakan soal-soal rutin, namun ketika soal tersebut dikonstruksi kedalam soal tidak rutin, siswa mengalami kesulitan dalam mengerjakan. Diperlukan upaya-upaya perbaikan untuk menangani masalah tersebut. Diantaranya dengan menciptakan suasana belajar yang kondusif agar siswa mengalami pembelajaran yang bermakna, diantaranya yaitu dengan mencoba berbagai model pembelajaran yang dianggap sesuai dengan keadaan dalam proses pembelajaraan. Salah satu model pembelajaran yang mendukung siswa dalam pemecahan masalah adalah model Auditory, Intellectually, Repetition (AIR). Tujuan penelitian ini adalah mendeskripsikan kemampuan pemecahan masalah matematis siswa setelah dibelajarkan dengan model pembelajaran AIR di kelas VIII SMP Negeri 1 Banjarmasin. Penelitian ini dirancang dan dilaksanakan dengan metode deskriptif sebanyak enam kali pertemuan. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII di SMP Negeri 1 Banjarmasin yang terdiri dari sembilan kelas, sedangkan sampelnya adalah siswa kelas VIII G. Teknik pengumpulan data menggunakan tes. Hasil penelitian menunjukkan bahwa Rata-rata kemampuan pemecahan masalh matematis siswa secara keseluruhan di kclas VIII SMP Negeri 1 Banjarmasin adalah sebesar 75,42 berada dalam kategori baik.
IMPLEMENTASI MODEL STUDENT TEAMS ACHIEVEMENT DIVISION UNTUK MENGEMBANGKAN KETERAMPILAN KOLABORATIF SISWA DALAM PEMBELAJARAN MATEMATIKA SMP
Authors: Nasih Ahmad , Pasani Chairil Faif , Kamaliyah Kamaliyah
Published: April 2022

Keterampilan Pembelajaran pada abad 21 disebut dengan istilah 4K yaitu kreatif, kritis, komunikatif, dan kolaboratif. Keterampilan sangat penting untuk dikembangkan, terutama keterampilan kolaboratif dan ilmu pendidikan sangat berperan penting untuk menumbuhkan dan mengembangkan keterampilan tersebut. Salah satunya bisa menggunakan model Student Team Achivement Division (STAD) untuk mengembangkan keterampilan kolaboratif tersebut. Tujuan penelitian ini untuk: (1) mengembangkan keterampilan kolaboratif siswa dalam pembelajaran matematika dengan penerapan model STAD, (2) mendeskripsikan hasil belajar siswa dalam pembelajaran matematika dengan penerapan model STAD, dan (3) menguji hubungan antara keterampilan kolaboratif siswa dengan hasil belajar siswa. Pada penelitian ini metode yang digunakan adalah metode quasi eksperiment. Bentuk desain pada penelitian ini adalah Equivalent time series. Sampel dalam penelitian ini adalah siswa kelas VIII A SMPN 24 Banjarmasin yang berjumlah 30 siswa. Teknik pengumpulan data penelitian ini adalah observasi dan tes. Data keterampilan kolaboratif yang diperoleh diuji memakai uji normalitas. Untuk hubungan keterampilan kolaboratif siswa dengan hasil belajar siswa memakai uji korelasi dan uji regresi. Hasil penelitian memperlihatkan bahwa: (1) penerapan model STAD bisa mengembangkan keterampilan kolaboratif siswa pada pembelajaran  matematika, (2) penerapan model STAD bisa memperbaiki hasil belajar siswa pada pembelajaran  matematika, (3) ditemukan hubungan yang kuat antara keterampilan kolaboratif siswa dengan hasil belajar matematika siswa.
PENERAPAN BLENDED LEARNING DENGAN COURSESITE DALAM PEMBELAJARAN MATEMATIKA DI KELAS X-TKJ 1 SMKN 1 PELAIHARI
Authors: Hakim Rahman Nul , Purba Harja Santana , Kusumawati Elli
Published: April 2022

Inovasi pembelajaran dewasa ini adalah pembelajaran menggunakan internet. Pembelajaran yang menggabungkan pembelajaran online dan tatap muka disebut blended learning. e-learning yang digunakan adalah coursesite. Penelitian ini bertujuan untuk mendeskripsikan bagaimana proses pembelajaran, hasil belajar, serta tanggapan siswa setelah penerapan bended learning. Metode penelitian yaitu deskriptif, subjek dalam penelitian ini siswa kelas X-TKJ 1 SMK Negeri 1 Pelaihari berjumlah 30 siswa, dan objeknya adalah hasil belajar. Instrumen penelitian yaitu tes, angket, dan lembar observasi. Hasil penelitian menunjukkan proses pembelajaran dalam klasifikasi baik, rata-rata hasil belajar siswa dalam klasifikasi baik, dan tanggapan siswa terhadap penerapan blended learning sebanyak 30% siswa sangat setuju, 30% siswa setuju, dan sisanya ragu-ragu
ANALISIS KEMAMPUAN PEMECAHAN MASALAH SISWA SMP DALAM MENYELESAIKAN SOAL CERITA DENGAN KONTEKS BUDAYA BANJAR
Authors: Jumiati Jumiati , Fajriah Noor , Danaryanti Agni
Published: April 2022

Tujuan dari penelitian ini adalah untuk menganalisis kemampuan pemecahan masalah siswa SMP dalam menyelesaikan soal cerita dengan konteks budaya Banjar tahun pelajaran 2019/2020. Penelitian ini menggunakan metode deskriptif dengan pendekatan kuantitatif. Populasi dari penelitian ini adalah siswa kelas VIII SMP Negeri se-Banjarmasin Barat. Pengambilan sampel dilakukan menggunakan teknik simple random sampling sehingga diambil sampel dari tiga sekolah dengan jumlah 345 siswa. Teknik pengumpulan data memakai tes soal uraian dan dianalisis berdasarkan langkah penyelesaian Polya menggunakan statistik deskriptif. Hasil dari penelitian ini menunjukkan bahwa kemampuan pemecahan masalah siswa SMP dalam menyelesaikan soal cerita dengan konteks budaya Banjar yaitu tergolong cukup dengan rincian sebagai berikut: (1) kemampuan memahami masalah siswa tergolong kategori cukup; (2) kemampuan membuat rencana siswa tergolong kategori baik; (3) kemampuan melaksanakan rencana siswa tergolong kategori cukup (4) dan kemampuan melihat kembali siswa tergolong kategori kurang.
Students' perceptions of the use quizizz as an online learning media for biology
Authors: Aýun Qurrota , Irwansyah Irsyad Purbha
Published: April 2022

During this covid-19 pandemic, Quizizz, as an Android-based educational game application, can be used to encourage students to be active and motivated in distance learning. This study aims to determine students' perceptions of the use of quizizz in motivating the students to study biology during online learning. The study population was all students of class IX MTs As-Saádah. The total number of respondents was 48 students. Data analysis was performed using the quantitative descriptive percentage technique. The research data was obtained by distributing questionnaires using the google form application. The questionnaire showed that 79.2% and 54.2% of students' perceptions regarding using the most preferred and good learning media were Quizizz. 45.8% of students showed interest in taking biology lessons using quizizz. 62.5% and 47.9% of students are motivated and enthusiastic about getting high scores. 89.6% and 66.7% of students agree that quizizz can improve their learning outcomes and concentration. 66.7% of students answered that the level of difficulty of quizizz questions was moderate, and 64.5% of students chose to agree that quizzz provided a new learning experience. The use of quizizz in online biology learning is a media recommendation that is appropriate, interesting and fun for students.
The inventory of local wisdom: Amanuban-Dawanese medicinal plant in Timor Tengah Selatan District
Authors: Tefu Meti OFI , Sabat Dian Ristiani
Published: April 2022

One of the preserved local wisdom of Dawanese (Amanuban) Timor Tengah Selatan District is using plants as traditional medicine. The Dawanese (Amanuban) knowledge of using herbal plants is inherited spontaneously based on the experience and skill of the ancestors. The knowledge is inherited orally and limited to family members and siblings. This research aims to invent species of plants, the plant parts, and their functions used by Dawanese (Amanuban) as traditional medicine. This research is descriptive qualitative research with observation and structured interviews as the instruments. The informants were chosen based on Purposive Sampling using Snowball Sampling. There are 40 informants in this research. The data in this research were analysed using the descriptive qualitative analysis technique and were tabulated in tables. Based on the research result, there are 103 species of plants used by Dawanese (Amanuban) as traditional medicine. Of the 103 kinds of plants used to treat 23 groups of diseases. The way to mix the traditional medicine by Dawanese (Amanuban) varies depending on the species of plants, the parts of plant used, and the species of disease cured. The general way used by Dawanese (Amanuban) is by boiling. The novelty of this research is the disclosure of local wisdom in the use of plants owned by the Dawanese (Amanuban) people. The results of this study are expected to support the preservation of biological and cultural resources. Therefore, it is necessary to identify further the Kulit Pahit (Melicope) plants that have not been identified to the species level.
Designing a module for learning plant biodiversity: An effort for conservation of local wisdom
Authors: Mumpuni Kistantia Elok , Susilo Herawati , Rohman Fatchur , Ramli Murni
Published: April 2022

This research aims to develop a module based on plant biodiversity and conservation in the Kudus area for high school students. The R&D research design, according to Borg & Gall, was implemented. The module was developed in five stages: research and information-gathering, planning; initial product development; preliminary field test; and product revision. Assessment and review of the module were performed by seven expert validators. Validity and reliability of the assessment instrument for the module were conducted and participated by 68 students. Thirty-one students became participants in the field test. Data were collected using a validation sheet and questionnaire. Data Analysis utilized excel, SPSS, and Rasch. Based on the assessment of validator experts, the module was declared valid. The module validation test gained an average score of 3.68 (very good). Students' responses showed that the Person measure was +3.22 logit, indicating that the students tended to agree with the proposed questions. The person and item reliability were 0.84 and 0.77, respectively. These values mean that the person reliability showed high consistency. The result of Rasch Analysis clarified the acceptance of students regarding the module both from Kudus and Non Kudus area. The results also showed students' interest and understanding of the issue of conservation and biodiversity, as well as their awareness of the local wisdom. It is recommended to develop a similar module as an effort of local potencies conservation.
Presentation Patterns and Surgical Management of the Complications of Thread Rhinoplasty
Authors: Jin Hong Ryul , Kim Su Jin
Published: April 2022

Objectives. Nonsurgical rhinoplasty using threads has gained popularity in recent years. While the benefits of this procedure have been emphasized, possible complications and their management are not well-known. This study aimed to present the surgical management and results of the complications of thread rhinoplasty.Methods. We retrospectively reviewed the medical records of seven patients who underwent revision rhinoplasty due to the complications of thread rhinoplasty from January 2018 to May 2021. The presentation of complications, detailed surgical procedures, and outcomes of revision rhinoplasty were reviewed.Results. Visible or extruded threads at the tip were the most common complication, followed by dorsum irregularity. All the threads were unabsorbed and intact in shape, even several years after insertion. Thread removal necessitated careful tissue dissection, resulting in the loss of tip support and dorsal irregularity. To restore the tip support and camouflage the dorsum shape, an autologous tissue graft was needed.Conclusion. Removal of threads at the tip and dorsum was accompanied by structural weakening and partial tissue loss, which required tip support restoration and dorsum camouflage.
Ulnar Wrist Pain in a Tennis Player: Case Review and Discussion
Authors: Logli Anthony L. , Loushin Stacy R. , Orlando Adam F. , Tetzloff Sabine , Kaufman Kenton R. , Kakar Sanjeev
Published: April 2022

» Ulnar-sided wrist pain is a common cause of debilitating wrist pain in stick-handling athletes. Due to the complexity of surrounding anatomy, the evaluation and diagnosis can be challenging.

» Injury of the triangular fibrocartilage complex (TFCC) is the most common cause of ulnar-sided wrist pain. Repetitive, unrestricted pronosupination, wrist deviation, and axial-loading activity, such as in tennis, place substantial stress on the TFCC.

» The ulnotriquetral (UT) ligament is a palmar thickening of the ulnar capsule arising from the palmar radioulnar (PRU) ligament of the TFCC. When injured, the UT ligament can be a source of acute or chronic ulnar-sided wrist pain. The ligament can avulse off bone, can rupture completely, or can split longitudinally.

» Arthroscopic-assisted repair is a safe, reliable, and effective treatment for UT ligament split tears and peripheral TFCC tears.

» Although the benefit of a team-based approach may be realized by most patients, high-performing, stick-handling athletes are part of a unique population who execute repetitive, extraordinary wrist movements. The high demand and functional requirement expected of the wrists require a uniquely tailored approach to return them to the same level of competitive play.
Treatment of Osteochondral Fractures After Acute Patellofemoral Instability
Authors: Medina Pérez Giancarlo , Barrow Brooke , Krueger Van , Cruz Aristides I.
Published: April 2022

» An osteochondral fracture (OCF) of the patella or the femur is a frequent sequela after an episode of acute patellofemoral instability.

» Patients commonly present with anterior knee pain after direct trauma to the patella or a noncontact twisting injury.

» Radiographs and magnetic resonance imaging (MRI) are the most common imaging modalities that are used to diagnose OCFs.

» Arthroscopy may be indicated in cases of displaced OCFs, and the decision regarding osteochondral fragment fixation or loose body removal depends on fragment size, location, and extent of injury.

» Most of the current literature suggests worse outcomes for patients with OCFs who undergo nonoperative treatment, no significant differences in outcomes for patients sustaining an acute patellar dislocation with or without an OCF, and inconclusive results concerning outcomes for patients treated with loose body removal compared with fixation.

» Current outcome data are limited by studies with low levels of evidence; therefore, well-designed randomized controlled trials are needed.
Remote active learning
Authors: Russell Ewan
Published: April 2022

Following the necessary shift to online learning in mathematics due to the COVID-19 pandemic, it was widely reported across the sector that encouraging students to engage in online synchronous sessions was very challenging. In this case study, the design and delivery of synchronous sessions for a large Year 1 mathematics module will be discussed. These synchronous sessions utilised an active learning approach which sought to address the difficulties in online learning through a focus on playfulness and games. This approach created opportunities for peer learning and successfully encouraged student engagement and interaction.
Facing Challenges in Remote Mathematics Education and Support by building a Community of Practice around Student-Staff Partnership
Authors: Casey Deidre , Fairclough Isabella , Perisic Vesna , Carey William , Smith Ann
Published: April 2022

Our active community of practice, developed from a weekly book club, formed through a shared interest in student-centred learning. Inspired by the book The Power of Partnership, this interdisciplinary group fostered and nurtured two practical mathematical applications through a partnership approach. In Munster Technological University academic support, including Mathematics and Statistics support, is offered to students through the Academic Learning Centre (ALC). Project 1 explored, through student-staff partnership, how best to promote the ALC. The project challenged our assumptions of how students would like to interact with the service. Project 2 focused on teaching mathematical analysis to a large cohort of year two students at the University of Southampton during the Covid-19 pandemic, elaborating on how small study groups, facilitated by student partners, were utilised to maintain a sense of connection and belonging, when possibilities for in-person teaching were extremely reduced. This paper discusses how a dispersed community of practice collaborated to enhance learning and teaching of mathematics.
Changes with time of Practitioners’ opinions of online Mathematics and Statistics Support
Authors: Gilbert Holly Jade
Published: April 2022

As an established part of the infrastructure of many higher education institutions in the UK and across the world, Mathematics and Statistics Support (MSS), was forced to move to an online setting as a result of restrictions put in place due to the COVID-19 pandemic. With institutions offering limited online support prior to the pandemic, MSS practitioners were mostly unprepared to deliver online provisions. Survey data from May 2020 gives a first look at the immediate response of practitioners to online MSS. Interview data from January/February 2021 explores opinions after a period of reflection, and survey data from June 2021, over a year on from the initial sample, provides a direct comparison in opinion of online support a year later. This paper explores these three datasets, investigating the practitioner perspective and offers an overall reflection of how MSS practitioners’ opinions of online support measures have changed from their “crisis-reaction” at the beginning of the pandemic to a more considered response as COVID-19 prevention measures are beginning to ease a year later.
Front matter
Authors: Rowlett Peter
Published: April 2022

Front matter
HUMANIZATION AND PERCEPTION OF EFFECTIVENESS OF BRAZILIAN HEALTHCARE SYSTEM
Authors: Pereira Bastos Sérgio Augusto , Pontes Ferreira Claudia
Published: April 2022

Research objective: Identify the factors of humanization that influence the perception of the effectiveness of healthcare services in Brazil by users (patients, companions, and family members) and professionals (doctors, assistants, and any others, directly or indirectly, linked with the provision of services) in the area.

Theoretical framework: Six guidelines of the National Humanization Policy (NHP) gave potential rise to constructs that are analyzed under the theoretical lens of the Autopoiesis Theory.

Methodology: Data is treated quantitatively from a survey of perceptions with a non-probabilistic sample. Exploratory factor analysis determined eight factors of humanization.

Results: The evidence indicated that the factors Professional Attention, Relational Attention, Expanded Clinic, and Valuing Workers' Technical Skills are positively related to the effectiveness of Brazilian healthcare services. Besides, there are differences in the perceptions of users and professionals concerning the effectiveness of humanization in healthcare services.

Originality: Based on public policy guidelines, through unprecedented quantitative research, the factors that form the construct of humanization in health services are highlighted.

Theoretical and practical contributions: The results contribute to humanization in healthcare services, especially in scenarios of the stress of the health system, which claims for substantive actions in the healthcare services social, technical, and political dimensions.
Implementação da Rede de Cuidados à Pessoa com Deficiência no Âmbito da Saúde Bucal a partir do Modelo de Coalizão de Defesa em Duas Regiões de Saúde no Brasil
Authors: Brandão Carneiro Joana Danielle , Moraes Bousquat Aylene Emília , Frazão Paulo
Published: April 2022

Objetivo da pesquisa: descrever as condições que favoreceram a conformação do subsistema da política pública e o processo de implementação da Rede de Cuidados à Pessoa com Deficiência no âmbito da Saúde Bucal (RCPD-SB) em duas regiões de saúde brasileiras semelhantes.

Enquadramento Teórico: o Modelo de Coalizão de Defesa (ACF) sustentou a interpretação dos resultados e a identificação do sistema de convicção e valores que orientou as coalizões formadas, suas estratégias, decisões governamentais, regras institucionais e efeitos obtidos no curso da implementação.

Metodologia: estudo de caso, em duas regiões de saúde semelhantes socioeconomicamente e na oferta de serviços, com análise documental e entrevistas com atores-chave.

Resultados: foram identificadas três coalizões nas regiões e uma delas divergente à orientação das políticas públicas que estruturavam a RCPD-SB. Apesar da semelhança socioeconômica e na oferta de serviços nas regiões, a implementação resultou em percursos distintos, nos aspectos cognitivos ou não cognitivos.

Originalidade: o uso do Modelo de Coalizão de Defesa para estudo de implementação de políticas no âmbito loco-regional e em torno da pessoa com deficiência é um aspecto positivo e inovador deste trabalho.

Contribuições teóricas e práticas: a análise a partir do ACF possibilitou observar que a região cujos condicionantes cognitivos estavam mais alinhados com as orientações do subsistema da política pública em torno da RCPD apresentou melhor integração e estruturação da rede de saúde, corroborando a importância da aprendizagem orientada pela política.

Palavras-Chave: Modelo de Coalizão de Defesa; Políticas Públicas; Saúde Bucal; Pessoa com Deficiência.
Entre a estabilidade (1995-2014) e a escolha pelos riscos de ruptura democrática: O Brasil na era do bolsonarismo
Authors: Aráujo Fernandes Antonio Sérgio ,  Carvalho Teixeira Marco Antonio , Ferreira Marques do Nascimento  Alex Bruno , Zuccolotto  Robson
Published: April 2022

O trabalho visa a discutir como o Brasil chegou à atual crise política sob a presidência de Bolsonaro com ameaça de ruptura das estruturas institucionais do país. Desde a redemocratização, em 1985, o país tem tido uma trajetória paradoxal: fez uma Constituição democrática em 1988, sofreu com a crise política do impeachment do primeiro presidente eleito depois de 21 anos de ditadura e viveu a hiperinflação, mas, mesmo assim, conseguiu chegar à estabilidade econômica e política entre 1995 e 2014. Entretanto, um novo paradoxo brasileiro é observado: quando tudo, em termos de bem-estar, estava evoluindo, inicia-se um estado de crise política aguda que desencadeia uma crise econômica crônica, mas que tem como desenlace a eleição em 2018 de Bolsonaro, cuja administração é desastrosa em todos os sentidos. Com esse cenário marcado pelo impasse é que se discute o que se espera para o país com a sucessão presidencial em 2022.
Salud cognitiva y física de los cuidadores informales de personas mayores con demencia: una revisión narrativa.
Authors: Parra-Rizo María Antonia , Sanchís-Soler Gema
Published: April 2022

El acto de cuidar a una persona con demencia repercute en un empobrecimiento cognitivo y físico que genera un declive en la salud del cuidador informal, y que afecta al buen rendimiento de sus tareas como cuidador. Conocer y cuidar la salud cognitiva y física del cuidador es de relevancia desde la atención sociosanitaria para garantizar el soporte principal de la atención a las personas mayores con un diagnóstico de demencia, es decir, cuidar al cuidador. Su conocimiento nos ayudará a establecer programas de prevención para adelantarnos a los posibles problemas emocionales como la depresión, y físicos, como las lesiones musculoesqueléticas. Con la presente revisión se pretende sintetizar los indicadores de salud cognitiva y física en cuidadores informales de personas mayores con demencia, que ayuden al establecimiento de futuras estrategias de intervención para preservar la salud de dichos cuidadores.
La comunicación de los profesionales de urgencias y su relación con la ansiedad y el cumplimiento terapéutico
Authors: Orcajada-Muñoz Irene , Leal Costa César , Díaz Agea José Luís , Hernández Ruipérez Tomás , Adánez Martínez María Gracia
Published: April 2022

Objetivos: Analizar la percepción de los pacientes sobre las habilidades de comunicación de los profesionales sanitarios en un Servicio de Urgencias Hospitalarias (SUH), y su relación con la ansiedad, el cumplimiento terapéutico y las variables sociodemográficas sexo y edad.

Método: Estudio descriptivo transversal que fue llevado a cabo en el SUH del Hospital Clínico Universitario Virgen de la Arrixaca en horario de 12 a 18 horas del 6 al 9 de junio de 2016. Se utilizaron diferentes instrumentos para evaluar la percepción de los pacientes sobre la comunicación, ansiedad y cumplimiento terapéutico.

Resultados: La muestra estuvo compuesta por 200 pacientes, con una mayor proporción con edad ≤ 20 años, de los cuales 106 (53%) fueron varones. Se obtuvo una correlación positiva y estadísticamente significativa (p<0,01) entre comunicación y el cumplimiento terapéutico.

Conclusiones: Cuando los pacientes del SUH perciben la comunicación de los profesionales de la salud como adecuada, hay un mejor cumplimiento terapéutico.
Cuestionario de empatía y violencia: Estudio psicométrico Preliminar.
Authors: Ferrer-Álvarez Raquel , Robles Sánchez José Ignacio , Alonso Gascón Miguel Raúl
Published: April 2022

Resumen: En las últimas décadas, ha aumentado exponencialmente la investigación sobre la relación entre la empatía y la violencia. Hay estudios que señalan correlaciones negativas entre la empatía y las conductas violentas, disruptivas, criminales, antisociales o agresivas. El objetivo de este estudio consistió en el diseño de un cuestionario para evaluar el grado de empatía y violencia en una misma escala.Para ello, se ha utilizado un conjunto de 13 ítems y X variables sociodemográficas, de los cuales, 7 de ellos están relacionados con la empatía y 6 con la violencia. Inicialmente se utilizo una muestra incidental compuesta por 297 participantes (89 hombres y 208 mujeres) con edades a partir de los 18 años. Para la realización de este estudio se extrajo un muestra aleatoria del 25% de la muestra total inicial. Se realizaron análisis de frecuencia, de fiabilidad, de correlaciones y un análisis factorial exploratorio. Este ofreció como resultado la extracción de dos factores denominados empatía (factor 1) y violencia (factor 2) los cuales explican el 67% de la varianza de los datos originales. Como resultado se realiza un nuevo Cuestionario de Empatía y Violencia (CEV) compuesto por 8 ítems y X variables sociodemográficas. En conclusión, este CEV se corrobora como un instrumento en castellano, mostrando unas propiedades psicométricas adecuadas para su utilización en el campo de la salud mental y se sugieren pasos a seguir para futuras investigaciones.Palabras claves: Cuestionario; Empatía; Violencia; Salud Mental.
Psicooncología pediátrica: el método fenomenológico hermenéutico en el estudio de las vivencias del personal sanitario implicado en las curas
Authors: Giosa Roberto
Published: April 2022

La psicooncología es una rama de la psicología de la salud relativamente nueva. La multidisciplinariedad que fomenta ha permitido, en el transcurso de los últimos 40 años, desarrollar un tratamiento más especializado que abarca los tres niveles de la enfermedad sugeridos por la OMS, el nivel físico, psicológico y social. Esto, para el personal sanitario implicado en la cura, supone un mayor esfuerzo laboral, tanto en el ámbito clínico como en el emotivo. En el presente artículo, tras una pequeña introducción histórica a la psicooncología pediátrica y al modelo de curación actual, el “triángulo pediátrico”, ha sido presentado el modelo de investigación empleado en el estudio de las vivencias de un grupo de enfermeros del departamento de oncología pediátrica del Hospital General Universitario de Alicante, España. La investigación, que ha sido realizada entre Abril y Junio de 2017, con el método presentado, ha señalado la importancia de crear un espacio en el que las personas implicadas en la cura del cáncer infantil puedan poner en común sus vivencias, enfatizando así sobre los recursos que cada una de ellas posee.El método fenomenológico-hermenéutico, presentado aquí desde sus raíces filosóficas, permite asomarse al mundo laboral del personal entrevistado, facilitando por un lado un mayor conocimiento sobre los temas de la oncología pediátrica y, por otro lado, permitiendo a las personas mismas reflexionar sobre sus “mundos internos”, con lo que esto, a nivel clínico y de reducción del estrés, supone.
Prevalencia de factores psicosociales de riesgo cardiaco en cardiópatas en rehabilitación
Authors: Valls Esperanza
Published: April 2022

La promoción de programas multidisciplinares de prevención y los avances en intervención cardíaca han mejorado el pronóstico de la enfermedad cardiovascular (ECV) aunque sigue siendo la principal causa de muerte en adultos de mediana edad. Los programas de rehabilitación cardíaca (PRC) inciden en modificar los posibles factores de riesgo cardíaco (FRC) implicados, incluidos los predisponentes psicosociales (emocionales, de personalidad y comportamentales) que son el objetivo prioritario de las intervenciones psicológicas inmersas en ellos. El objetivo del presente estudio es analizar la prevalencia de dichos factores psicosociales en una muestra española (N: 905; 82% varones), incluida en un PRC y detectar la diferente prevalencia según el género, el riesgo cardíaco y la edad.

Resultados: prevalencia en depresión: 29%, afecto negativo: 33,4%, expresión de ira: 30,4% y ansiedad 20%.  El 17,3% presentó personalidad tipo-A (PCTA) y obtuvo una reducida calidad de vida el 25,3% y bajo apoyo social el 12,5%. Las mujeres mostraron mayor psicopatología emocional y menor uso de estrategias activas y PCTA. Además, con mayor riesgo cardiológico se obtuvo un perfil psicológico más adverso mientras que,  según la edad, los más jóvenes presentaron mayor prevalencia de factores psicosociales. Conclusión: por su elevada prevalencia, se hace necesario enfatizar la atención a los factores psicosociales en los programas de rehabilitación y hacerlo diferencialmente conforme los perfiles de los usuarios.
Enfermedad renal crónica avanzada: ansiedad, depresión y percepción de amenaza
Authors: Lacomba-Trejo Laura , Mateu-Mollà Joaquín , Cabajo Álvarez Eva , Oltra Benavent Ana María , Galán Serrano Antonio
Published: April 2022

Marco teórico: la percepción de su enfermedad que tengan los pacientes con enfermedad renal crónica avanzada (ERCA) puede generar sintomatología depresiva y ansiosa. El objetivo general fue valorar la sintomatología ansiosa y depresiva y la percepción de amenaza de la enfermedad de pacientes con ERCA.

Método: 70 pacientes (80% barones), de entre 38-88 años (M=68,88; DT= 9,98) fueron evaluados mediante: la Escala Hospitalaria de Ansiedad y Depresión y la de Percepción de amenaza de la enfermedad. Se realizaron análisis descriptivos, pruebas t, dde Cohen y correlaciones de Pearson.

Resultados: un 41,79% presentaba sintomatología ansiosa y un 25,38% depresiva, percibían su enfermedad como moderadamente negativa. La sintomatología emocional fue mayor en las mujeres y se asoció con la percepción de amenaza de la enfermedad. 

Conclusiones: es necesario conocer los factores de riesgo para desarrollar programas de intervención que incidan en ellos y favorezcan la salud física y mental del paciente.

 

 Palabras clave: Enfermedad Renal Crónica Avanzada, Ansiedad, Depresión, Percepción de Amenaza de la Enfermedad, Factores de riesgo
Association between Health-Related Quality of Life and Coping Strategies of Gastrointestinal Cancer Caregivers: A Rasch Analysis
Authors: Ikhsan Nur Afrina , Mahmud Zamalia , Abdullah Nik Nairan
Published: April 2022

The number of gastrointestinal (GI) cancer patients in Malaysia is rising. Caregivers need to perform their responsibilities as they spend most of their time providing care for the patient in their homes. To what extend does health-related quality of life (HRQOL) of GI caregivers relates to coping strategies of caregivers are unknown and yet to be investigated. This study investigates the caregivers’ response pattern towards HRQOL and coping strategies survey items across several domains and the association between HRQOL and coping strategies of the caregivers. This study used Rasch measurement model in the analysis of survey data gathered from 323 GI cancer caregivers from three public hospitals. Data were collected using HRQOL and Coping strategies instruments administered to the GI caregivers. It was found that four items (QOL_9, QOL_20, QOL_25 and QOL_31) under the Burden domain are among the most difficult to endorse by GI caregivers in the HRQOL items. Meanwhile, two items (COPE4 and COPE11) under the Substance Use domain in the coping strategies constructs are most difficult to endorse by GI cancer caregivers. This study also discovered that majority of caregivers who have issues with mental strain, disruptiveness, daily focus and sleep disruption applied positivity adaptation and use of emotional support as their coping strategies.
The Pillars of Health: Influence of Multiple Lifestyle Behaviors on Body Mass Index and Depressive Symptoms in Adult Twins
Authors: Duncan Glen E. , Avery Ally R. , Tsang Siny , Watson Nathaniel F. , Williams Bethany , Turkheimer Eric
Published: April 2022

Background: Guidelines promoting healthy lifestyles are cornerstones of chronic disease prevention and treatment. The purpose of this study is to investigate independent and joint associations of five key health behaviors with health outcomes (body mass index (BMI kg/m2) and depressive symptoms) in adult twins. Methods: We included 6,048 twin pairs from a community-based registry. Five key health behaviors were: (1) ≥ 8 hours of sleep per night, (2) ≥ 5 servings of fruits and vegetables daily, (3) ≤ 2 hours sedentary time per day, (4) ≥ 150 min of moderate-to-vigorous physical activity (MVPA) per week, and (5) no smoking. We analyzed phenotypic associations between behaviors and outcomes; whether phenotypic associations were confounded by additive genetic and shared environmental factors within twin pairs (“quasi-causal” associations); and which behaviors, considered simultaneously, had the largest associations with outcomes. Results: We found negative phenotypic associations between number of behaviors achieved with BMI and depressive symptoms score (ps < 0.05). Associations remained significant, though attenuated, when controlling for genetic and shared environmental factors, and demographics, for depressive symptoms score but not BMI (p < 0.05). Quantitative variable importance measures derived from regression tree models showed sedentary time and MVPA were the most important variables in partitioning twins with different BMI, and smoking and sedentary time for partitioning twins with different depressive symptoms score. Conclusions: Achievement of commonly endorsed health behaviors is associated with lower BMI (especially sedentary and MVPA targets) and depressive symptoms score (especially sedentary and smoking targets). This provides further support of health behavior promotion to improve health outcomes.
iEnhancer-DCLA: Using the original sequence to identify enhancers and their strength based on a deep learning framework
Authors: Liao Meng , Zhao Jian-ping , Tian Jing , Zheng Chun-Hou
Published: April 2022

Enhancers are small regions of DNA that bind to proteins, which enhance the transcription of genes. The enhancer may be located upstream or downstream of the gene. It is not necessarily close to the gene to be acted on, because the entanglement structure of chromatin allows the positions far apart in the sequence to have the opportunity to contact each other. Therefore, identifying enhancers and their strength is a complex and challenging task. In this article, a new prediction method based on deep learning is proposed to identify enhancers and enhancer strength, called iEnhancer-DCLA. Firstly, we use word2vec to convert k-mers into number vectors to construct an input matrix. Secondly, we use convolutional neural network and bidirectional long short-term memory network to extract sequence features, and finally use the attention mechanism to extract relatively important features. In the task of predicting enhancers and their strengths, this method has improved to a certain extent in most evaluation indexes. In summary, we believe that this method provides new ideas in the analysis of enhancers.
Rhizonium alarensis sp. nov., and Rhizonium halophilensis sp. nov., isolated from the nodule and rhizosphere of Lotus japonicus
Authors: Wan Chuanxing , Shen Hongling , Luo Xiaoxia , Xia Zhanfeng
Published: April 2022

Two strains (TRM95111T and TRM95001T) of Gram-stain-negative, aerobic, rod-shaped mycrobacteria were isolated from the nodule and rhizosphere of Lotus japonicus grown in the campus of Tarim University in Alar, Xinjiang, China. Strain TRM95111T and strain TRM95001T shared 93.1% 16S rRNA gene sequences similarity with each other and had 98.2% and 97.9% 16S rRNA gene sequence similarity to the closest species Rhizobium subbaraonis JC85T and Rhizobium halotolerans AB21T, respectively. Phylogenetic analyses based on 16S rRNA gene sequences, two housekeeping gene sequences (recA, atpD) and core genes showed that two strains belonged to the genus Rhizobium. The values of digital DNA-DNA hybridization (dDDH) between strain TRM95111T and the closest strains R. subbaraonis JC85T and R. azooxidifex Po 20/26T were 21.8% and 21.4%, respectively. The dDDH values between strain TRM95001T and the closest strains R. halotolerans AB21T and R. flavum YW14T were 22.6% and 26.7%, respectively. Whole genome average nucleotide identity (ANI) values of the strain TRM95111T were 75.6%-77.5% and strain TRM95001T were 79.2%-79.6%, compared to their closely related strains. The G + C content values of strain TRM95111T and TRM95001T were 65.1 mol% and 60.7 mol%, respectively. Two isolates contained predominant quinone of Q-10 and the major fatty acids was C18:1ω7c. The polar lipids of strain TRM95111T included unidentified aminophospho lipids (APL1-3), unidentified phospholipids (PL1-2), phosphatidylcholine (PC), unidentified lipids (L1-5) and phospholipids of phospholipids of unknown structure containing glucosamine (NPG), compared to the polar lipids of strain TRM95001T including unidentified aminophospho lipids (APL1-3), unidentified phospholipids (PL1-2), phosphatidylcholine (PC), unidentified lipids (L2-5), hydroxy phosphatidy ethanolamine (OH-PE) and phospholipids of phospholipids of unknown structure containing glucosamine (NPG). Nodulation tests showed that two strains could induce nodules formation in L. japonicus. Based on genomic, phenotypic and phylogenetic analyses, strain TRM95111T and strain TRM95001T are suggested to represent two new species of the genus Rhizobium, whose names are proposed as Rhizobium alarensis sp. nov. and Rhizobium halophilensis sp. nov. The type strains are TRM95111T (= CCTCC AB 2021116T = JCM34826T) and TRM950011T (= CCTCC AB 2021095T = JCM34967T), respectively.
A novel nitidine chloride nanoparticle overcomes the stemness of CD133 + EPCAM + Huh7 Hepatocellular Carcinoma Cells for liver cancer therapy
Authors: Li Danni , Zhang Qiying , Zhou Yuzhu , Zhu Hua , Li Tong , Du Fangkai
Published: April 2022

Background: Stemness of CD133+EPCAM+ hepatocellular carcinoma cells ensures cancer resistance to apoptosis ,which is a challenge to current liver cancer treatments. Here we discovered that a novel nitidine chloride nanoparticle (TPGS-FA/NC, TPGS-FA: folic acid modified D-α-tocopheryl polyethylene glycol 1000 succinate , NC: nitidine chloride) targeted Huh7 human hepatocellular carcinoma and promoted its apoptosis in mice and cells. CD133 expression regulates AQP3 expression, promoting to increase the stemness properties of hepatoma cells. Importantly, AQP3 is association with stimulation and nuclear translocation of STAT3 with a increasing expression level of CD133 . Methods: Cell viability was assessed by MTT and colony assays.TPGS-FA/NC nanoparticles were assayed by using confocal microscopy targeting Huh7 Hepatocellular Carcinoma Cells . A sphere culture technique was used to enrich cancer stem cells (CSC) and sort the CD133+EPCAM+ Huh 7 cells by magnetic-activated cell sorting assay. The proteins were examined by immunohistochemistry and western blotting assay. Result: TPGS-FA/NC nanoparticles reduced the CD133+EPCAM+ Huh7 cells numbers in vitro. Furthermore, its time-dependently suppressed the AQP3/CD133/STAT3/JAK signaling pathways. Nitidine chloride nanoparticles therapy prevented and treated hepatocellular carcinoma in mice without adverse effects. Conclusions: TPGS-FA/NC is shown to a promising and safe drug against liver cancer therapy via AQP3/STAT3/CD133 axis.
In Vivo CRISPR Screens Identify RhoV as a Pro-Metastasis Factor of Triple-Negative Breast Cancer
Authors: Shao Zhi-Ming , Jin Ming-Liang , Gong Yue , Ji Peng , Hu Xin
Published: April 2022

Background: Metastasis is the main death reason for triple-negative breast cancer (TNBC). Thus, identifying the driving genes associated with metastasis of TNBC is an urgent need. CRISPR screens have dramatically enhanced genome editing and made it possible to identify those genes associated with tumor metastasis. Methods: Here, we performed customized in vivo CRISPR screens targeting metastasis-related genes obtained from transcriptome analysis. By applying Cox proportional hazard regression models, we developed and verified a three-gene signature (RhoV, TSNARE1 and C19orf33) to predict the disease-free survival in TNBC. Next, immunoprecipitation and LC-MS/MS were conducted to explore the metastasis mechanism of RhoV.Results: The three-gene signature successfully predicts the disease-free survival in TNBC. Furthermore, our data demonstrated RhoV as a key gene involving in tumor metastasis, which was frequently upregulated in TNBC and correlated with poor survival. Knockdown of RhoV significantly suppressed cell invasion, migration and metastasis both in vitro and in vivo. In addition, we explored the physically association between RhoV and activated EGFR and verified the association was dependent on GRB2 through a specific proline-rich motif in N-terminus of RhoV. Conclusions: Taken together, our research firstly reveals that RhoV serves as an EGFR-mediated metastasis mechanism activator and thus provides a mechanistic basis for TNBC metastasis and may be a valuable therapeutic target.