bluuebunny/crossref_metadata_2025 huggingface dataset:
T Regulatory Cells in Relapsed/Refractory Chronic Lymphocytic Leukemia Treated with High Dose Methylprednisolone and Rituximab
Authors: Pileckytė Regina , Pileckytė Regina , Zvirblis Tadas , Matuzeviciene Reda , Janiulioniene Ausra , Griskevicius Laimonas
Published: December 2020

Higher circulating T regulatory cell (Treg) numbers have been found in untreated patients with chronic
lymphocytic leukemia (CLL) compared to healthy subjects and correlated with progressive disease as well
as time to first treatment in low-risk patients [1]. Some agents can reduce Treg numbers in CLL patients,
but there are no data on the prognostic role of Treg dynamics and patient outcome. We present data from
the LT-CLL-001 study, in which the clinical benefit of dose-dense high dose methylprednisolone (HDMP)
and rituximab (Rtx) combination in relapsed or refractory high-risk patients with CLL was evaluated [2].
During the study, the change of T regulatory cell frequencies was measured in relation to overall response
rate (ORR), progression-free survival (PFS), and overall survival (OS). Twenty-nine CLL patients with
clinically or biologically high-risk disease were included. Treg frequency was evaluated at screening, after
three treatment courses, and at the end of therapy. Significant reduction of the median frequencies of Treg
during treatment was observed: median (range) of Treg0-3 after three treatment courses was 2.14% (-1.84%-
9.42%), p < 0.001 and median (range) of Treg0-6 was 1.01% (-2.95%- 8.35%, p = 0.004). Patients with
deeper Treg reduction between screening and three treatment courses had significantly better PFS and OS
(Table 1 & 2). Our data for the first time show that HDMP and Rtx combination reduces Treg frequency in
pretreated CLL patients. Early and deeper Treg reduction is an independent prognostic factor for longer PFS
and OS. (ClinicalTrials.gov identifier: NCT005 58181).
Complex Spinal Dorso-Ventral Stabilization in the Elderly – Is Age a Limiting Factor? Retrospective Case Series of 53 patients
Authors: Ewelt Christian , Yavuz Murat , Warneke Nils , Schwake Michael , Schröteler Juliane , Zawy Alsofy Samer , Stummer Walter , Klingenhöfer Mark , Ewelt Christian
Published: December 2020

Objective: Medical progress is increasingly confronting us with the question of whether complex surgical
spinal care can be performed safely, even in older patients. This study is intended to contribute to the
clarification of this question.
Methods: 53 patients with a minimum age of 70 years at time of surgery were retrospectively enrolled in a
single center setting. All patients were treated with complex dorsoventral instrumentation and corpectomy
due to different pathologies. Because of neurological deficits and untreatable pain, no control group of
patients could be defined in advanced age by withholding necessary surgery. The ethical committee would
not accept this.
Results: Most patients benefited from the procedure with regard to pain (97%), sensori-motor deficit (89%),
and finally, immobility (82%). The duration of surgery, the amount of transfused red blood cell concentrates,
and the length of hospital stay were not predictors of a poor overall outcome. It was shown that the risk of
postoperative complications increased due to the number of preoperative secondary diagnoses.
Conclusion: Therefore, not the patients’ age alone is of prime importance for individual surgical treatment
decisions, but the number of secondary diagnoses plays a more important role. Especially in that older
population, patients benefit from surgical therapy; regardless, it could be complex.
Study of the species composition of micromycetes of drained soils of the Trubizh river basin
Authors:   National University of Life and Environmental Sciences of Ukraine, Ladyka M. M. , Rubezhnіak I. G. ,   National University of Life and Environmental Sciences of Ukraine, Doroshenko A. V. ,   National University of Life and Environmental Sciences of Ukraine
Published: December 2020

The study of the quantitative and qualitative composition of the soil microbiota, which adequately reflects the degree of anthropogenic load, can be applied as an indicator of assessment of the ecological status of the soil of anthropogenically transformed biogeocoenosis.The aim of the article is to analyze the species composition of micromycetes of drained soils of the Trubizh river Basin as an indicator of the ecological condition of the soil of different degrees of economic activity. For microbiological analysis samples of organogenic (lowland deep and medium peat soils) and mineral (meadow-chernozemic) soils were used. The samples selected from four experimental plots with different degrees of anthropogenic load. In particular, the first plot is a long-term use fallow (more than 15 years) on deep peatlands, the second one is a field with corn for grain on medium peatlands. The third plot is a field with post-harvest soybean residues on medium peatlands and fourth one is fallow with annual and perennial grasses on meadow-chernozemic soils. Soil samples were taken from the root layer at a depth of 0-5, 5-10 and 10-20 cm according to the current DSTU. Isolation of micromycetes was carried out by dilution method of soil with the object of estimation of the concentration (number of colonies, micromycetes). The count of micromycetes was estimated on surface of potato-glucose agar and Chapek's agar plates and was determined by the number of colony forming units (CFU). It was established that in the plot with increased anthropogenic impact (field with corn for grain on medium peatlands) the total number of isolated micromycetes was twice less than in plots of fallow lands and soybean. There was observed very poor species compositions (13 species). 2 species (15%) of Zygomycota, where predominant concentration was Mucor plumbeus in the soil layer 0-20 cm and 11 species (85%) of Ascomycota were found. In all plots, the basis of micromycete complexes was formed by fungi-destructors of plant remains and root secretions of the genus Penicillium. The micromycetes of drained soils of the Trubizh river Basin was presented the biggest phylum Ascomycota (83-95.5%) and the phylum Zygomycota (4.5-17%) also.
Thirty-Six-Month Follow-up of Diaphragm Pacing with Phrenic Nerve Stimulation for Ventilator Dependence in Traumatic Tetraplegia: The Way Forward for Spinal Cord Injury Rehabilitation in a Developing Country
Authors: Sharma Vyom , Jafri Haris , Roy Nilanjan , Dangi Manish , Kataruka Mohit
Published: December 2020

Respiratory failure and chronic ventilator dependence in tetraplegics following cervical injuries located high on the spine (C1–C3) constitute significant challenges in the rehabilitation of patients given the occurrence of repeated hospitalizations and an ever-increasing financial burden. A 30-year-old man presented with posttraumatic tetraplegia following an unstable injury at the C1–C2 level with cord compression; he was managed by posterior stabilization and decompression followed by ventilator dependence and no rehabilitation until 6 months postinjury. We implanted phrenic nerve stimulator electrodes bilaterally for indirect diaphragm pacing by an implantable pulse generator that allowed for weaning from mechanical ventilation and spontaneous ventilator-free breathing at 20 weeks post-implantation and which facilitated post-tetraplegia rehabilitation. At 36 months after implantation, the patient is ventilator- free without any procedure-related complications or respiratory infections. Diaphragm pacing with phrenic nerve stimulation may be a way forward for ventilator-dependent tetraplegics in developing countries to pursue effective rehabilitation and improved quality of life.
Can High-Sensitivity C-Reactive Protein Levels Predict Functional Outcome Following Epidural Steroid Injection in Patients with Lumbar Disc Disease?
Authors: Gopireddy Rajesh , Rangasamy Karthick , Goni Vijay G. , Vatsya Pulak , Behera Prateek , Batra Yatindra K. , Vaishnavi Chetana
Published: December 2020

Study Design: Prospective cohort study.Purpose: Inflammatory cytokines produced at the site of disc herniation are considered as pain generators in patients with lumbar disc disease. Whether a high-sensitivity C-reactive protein (hs-CRP) assay can be used in order to predict the quantum of inflammation surrounding nerve roots is a matter of investigation. This study aimed to evaluate the association of hs-CRP level and functional outcomes measured by the Modified Oswestry Low Back Pain Disability Questionnaire (MODY) before and after epidural steroid injection (ESI) in patients with lumbar disc disease.Overview of Literature: Although many studies examining the role of hs-CRP levels and lumbar pain have been published previously, the results are equivocal, and there is no clear consensus regarding which patients will benefit from an ESI.Methods: This was a prospective study, with 77 patients in the study group and 23 participants in the control group. Baseline hs- CRP levels were obtained for both groups. Study group patients received a single ESI and were subjected to detailed pre- and postprocedure evaluation using MODY scores. For this group, hs-CRP levels were measured at 1 and 2 months after injection.Results: Out of 77 patients, 52 had acute and 25 had chronic low back pain. Thirty-six patients with acute pain obtained significant improvement, while 16 had an insignificant response to the ESI. None of the chronic cases had a significant response. The mean baseline hs-CRP (mg/L) among the study group (29.83±10.43) was significantly higher than for the controls (10.26±2.783). The baseline hs-CRP among acute cases, where post ESI MODY score at 2 months had significant reduction, was 32.19±5.126, and those with insignificant reduction was 18.13±7.949 (p <0.001).Conclusions: Baseline hs-CRP levels can be used to prognosticate the outcome following ESI in patients with acute lumbar disc disease, with radicular pain refractory to physiotherapy and analgesics.
Outlines of Pyrrhonism
Authors: Empiricus Sextus
Published: December 2020

The first Ukrainian translation of the classic work of ancient skepticism, Sextus Empiricus’ Outlines of Pyrrhonism, made by D. of Sc. Philology Lesia Zvonska under the scientific editorship of Dr. of Sc. in Philosophy. Oleg Khoma.
Dampak Pendekatan Realistic Mathematics Education Terhadap Keterampilan Berpikir Kritis Pada Siswa Sekolah Dasar
Authors: Puspita Vivi , Yuhelman Nofri , Rifandi Ronal
Published: December 2020

Abstract: The low ability of students in solving math problems illustrates the low ability of students in critical thinking. So this research aims to determine the impact of a realistic approach to mathematics education on students' critical thinking abilities. This research is a quasi experimental study with the type of non-equivalent control group design. The research subjects were 29 elementary school students. The results showed t-hitung=6.52 and t-tabel = 1.69092 where t_hitung is greater than the ttabel so that there is a positive influence of the use of Realistic Mathematics Education on the thinking skills of elementary school students, especially in mathematics learning            Abstrak:  Rendahnya kemampuan siswa dalam menyelesaikan masalah matematika menggambarkan rendahnya kemampuan berpikir kritis siswa. Maka penelitian ini bertujuan untuk mengetahui pengaruh pendekatan realistik pendidikan matematika terhadap kemampuan berpikir kritis siswa. Penelitian ini merupakan penelitian eksperimental semu dengan jenis desain non-equivalent control group. Subjek penelitian adalah 29 siswa Sekolah Dasar. Hasil penelitian menunjukkan dan  = 1,69092 dimana  lebih besar dari pada  sehingga ada pengaruh positif penggunaan Pendidikan Matematika Realistik terhadap keterampilan berpikir siswa sekolah dasar, khususnya dalam pembelajaran matematika
Game Edukasi berbasis Android: Urgensi Penggunaan, Pengembangan dan Penguji Kelayakan
Authors: Muhajarah Kurnia , Rachmawati Farida
Published: December 2020

Abstract: The development of information technology today has been able to package the conditions and realities of learning to be more attractive. Educational games are games or fun activities that contain educational content and their use, which is a necessity. This research is a library research. The data was extracted and analyzed in depth using the qualitative theory of Bogdan and Cresswell. The results showed that the ability to absorb each student in learning was strongly influenced by the learning experience, mode, modality and learning style.There are differences regarding this matter, it can be accommodated by the use of educational games as learning media. The use of educational games does not conflict with behaviorism and cognitivism theories. On the other hand, the use of android-based educational games serves to make it easier forstudents to operate and use them. However, because of its simplicity, the use of educational games must be tested first through strict instruments by experts to be able to meet the marketing standards, test content and maximize its use.Abstrak: Perkembangan teknologi informasi dewasa ini telah mampu mengemas kondisi dan realitas pembelajaran menjadi lebih menarik. Game edukasi merupakan permainan atau aktivitas menyenangkan yang memuat konten pendidikan dan penggunaanya, merupakan sebuah keniscayaan Penelitian ini merupakan penelitian kepustakaan. Data digali dan dianalisis secara mendalam menggunakanteori kualitatifnya Bogdan dan Cresswell. Hasil penelitian menunjukkan bahwa kemampuan daya serap masing-masing peserta didik dalam pembelajaran sangat dipengaruhi oleh pengalaman belajar, modus, modalitas dan gaya belajarnya.Adanya perbedaan mengenai akan hal ini, bisa diakomodir dengan penggunaan game edukasi sebagai media pembelajaran. Penggunaan game edukasi ini tidak bertentangan dengan teori behaviorime dan kogntivisme. Di lain sisi, penggunaan game edukasi berbasis android, berfungsi untuk memudahkan peserta didik dalam pengoperasian dan penggunaannya. Namun demikian, karena kemudahannya, penggunaan game edukasi harus diujilayakkan dahulu melalui instrumen yang ketat oleh para ahli untuk dapat memenuhi standar edar, uji konten dan memaksimalisasi pemanfaatannya.
Tradisi Siklus Hidup Masyarakat Perkotaan di Era Normal Baru
Authors: Melina Mita , Sany Ulfi Putra , Mustolehudin Mustolehudin
Published: December 2020

Tradisi merupakan suatu adat kebiasaan atau budaya yang dilakukan secara terus-menerus dalam lingkup kehidupan suatu masyarakat. Umumnya tradisi dilaksanakan di lingkup pedesaan, atau daerah-daerah terpencil yang masih mempraktikkan budaya-budaya lokal dan jauh dari pengaruh globalisasi. Berbeda dari tradisi yang lazim dilakukan di pedesaan, kajian ini membahas tradisi yang hidup di lingkup perkotaan. Penelitian yang dilakukan dengan pendekatan kualitatif ini, bertujuan untuk mengungkap tradisi siklus hidup yang dilakukan masyarakat di Kota Semarang pada masa adaptasi kebiasaan baru. Dalam penelitian ini ditemukan fenomena bahwa tradisi yang dilakukan masyarakat perkotaan di era normal baru mengalami perubahan disebabkan adanya Pembatasan Sosial Berskala Besar (PSBB) akibat pandemi virus Covid 19. Meskipun terkendala dengan wabah Corona, tradisi ini tetap dilestarikan dengan mematuhi protokol kesehatan. Tradisi ini mengakomodasi nilai-nilai ajaran Islam dan tradisi lokal. Melalui tradisi siklus hidup ini telah terjadi akulturasi Islam dan budaya Jawa. Dalam ritual upacara mapati, mitoni, puputan, selapanan dan tedhak siten terdapat nilainilai ajaran Al Qur’an pada tradisi tersebut.
Mengilhami Kreativitas Keberagamaan Masyarakat Melalui Perjumpaan Islam dan Patuntung di Tanah Toa Kajang
Authors: Sylviah Sylviah , Muslim Abu
Published: December 2020

Relasi Islam dan agama lokal sebagai bagian dari perjumpaan keberagamaan dan kebudayaan masyarakat, merupakan kajian khazanah keagamaan yang salah satu tujuannya adalah untuk melihat bagaimana eksistensi agama dan kepercayaan lokal itu dalam menghadapi pengaruh doktrin dan narasi keberagamaan dari luar. Setelah melakukan wawancara, observasi, telaah dokumen naskah, dan inventarisasi tradisi lisan, dengan mengacu pada pendekatan sejarah, penelitian ini menemukan bahwa Tanah Toa Kajang sebagai semua komunitas lokal dengan kepercayaan patuntung yang telah mandarah daging, dapat tetap menjalankan ajaran keagamaan yang dianut, dengan melakukan adaptasi kultural dengan Islam sebagai agama yang hadir dan menawarkan perspektif baru tentang perilaku keberagamaan, namun oleh komunitas kajang justru dengan idealisme dan kepantuntungan yang dimiliki justru menklaim bahwa pada prinsipnya ajaran yang dibawa itu adalah ajaran yang juga telah lama dipegangi. Sesungguhnya Islam itu pada dasarnya lebih duluan lahir di tana toa kajang kemudian tersebar ke luar. Bangunan narasi ini menunjukkan bahwa kepercayaan Patuntung berhasil melakukan negoisasi keberagamaan dengan Islam, tanpa harus ada yang menaklukkan dan ditaklukkan. Dengan kreatifitas yang mereka miliki, mereka berhasil menerjemahkan Islam sesuai dengan lokalitas dimana mereka berada.
Reproductive Characteristics of Peranakan Etawa and Kacang Goats in Different Maintenance Systems in the Toari District, Kolaka Regency
Authors: Mogiye Saneng Lega , Nafiu La Ode , Amrullah Pagala Muhammad
Published: December 2020

Toari sub-district has a population of 4,434 head or 18.47% of the total 24,003 head of the goat population in Kolaka Regency. This study aims to determine the reproductive characteristics of Etawa crossbreed goats and bean goats in different maintenance systems in the Toari District. The population in this study were all breeders of goat etawa (PE) and bean goats in the Toari Subdistrict with the research sample of Ranomentaa, Rano Jaya, Lakito and Toari villages. The sampling method is determined by purposive sampling, as well as the data used are primary and secondary. Primary data were obtained through interviews of 100 respondents while secondary data were obtained from the District, village and related government offices. The results showed that the reproductive characteristics (the distance of calving, first mating, and kidding rate) of Etawa (PE) goats were generally higher than those of goat nuts in intensive, semi-intensive and extensive system maintenance.
Predict Students' Performance by Using J48 Algorithm
Authors: Tun Myo Thandar , Htay Yin Yin
Published: December 2020

The critical issue to the academic community of higher education is to monitor the progress of students’ academic performance. We can use data mining techniques for this purpose. J48 algorithm is one of the famous classification algorithms present today to generate decision trees in data mining technique. The data set used in this study is taken from University of Computer Studies (Mandalay). Weka machine learning tool is applied to make classification. In this work, we tested result classification accuracy was computed. This J48 classification algorithm give accuracy with 78.2%.
Mineralogische Analyse einer Sandprobe von Areal Morro Branco in Porto Grande – AP
Authors: Andrade Alexsandrea Ricarda Pinheiro , Pereira Iara Rafaelle Silva , Dias Claudio Alberto Gellis de Mattos , Fecury Amanda Alves , Dendasck Carla Viana , Dantas Antônio de Pádua Arlindo
Published: December 2020

Die Gemeinde Porto Grande wurde am 1. Mai 1992 gegründet und liegt in der nördlichen Region des Bundesstaates Amapá mit einer Fläche von 4 400 km2. Das Ziel dieser Arbeit ist die semiquantitative Analyse einer Sandprobe von Areal in der Gemeinde Porto Grande, die probe durchgeführt hat einige grundlegende Schritte wie: Trocknung, Feuchtigkeitsbestimmung, Bestimmung von Ton-, Schlick- und Sandfraktionen, Homogenisierung, Quarteamento und Partikelgrößenanalyse. Bei der Bestimmung der Luftfeuchtigkeit erhielten wir den Prozentsatz von 2,4%, und dies war die Differenz zwischen der Nassmasse und der Trockenmasse unserer Probe P1, nach dem Siebprozess wurde der Prozentsatz des in jedem Sieb zurückgehaltenen Materials berechnet, um die Leistung unseres Siebvorgangs zu analysieren, und schließlich wurde die Bestimmung der Tonfraktionen durchgeführt, die als Gewicht 0,17 g , Schlick mit einem Gewicht von 24,83 g und Sand mit einem Gewicht von 275 g. Am Ende der Tests können wir jedoch eine Anomalie in den Ergebnissen der Partikelgrößenanalyse beobachten, da das betreffende Sieb feucht wäre, wodurch das gesamte Feingranulatomometriematerial nicht passieren würde.
Hypnoteacing Sebagai Metode Alternatif Dalam Pembelajaran Materi Keagamaan
Authors: Istiani Nurul , Islamy Athoillah
Published: December 2020

Orientation in spiritual education does not always run smoothly. One of the obstacles is related to how to use the right learning method in order to teach students spiritual intelligence properly and optimally. This study aims to explain the application of the hypnoteaching method in spiritual learning. This type of research is qualitative research in the form of a literature review. The main data source of this research is Muhammad Noer's thoughts in his book entitled Hypnoteaching For Success Learning. Meanwhile, the secondary data sources used were various studies that were relevant to the object of this research discussion. The results of this study concluded that the hypnoteaching method is a learning method that combines the teaching and learning process with hypnosis. This method can be used as a method in the spiritual learning process. In its application, the hypnoteaching method emphasizes the cognitive, affective, and psychomotor aspects of students through positive suggestions. With these steps, it is hoped that a more effective and enjoyable spiritual learning process can be realized.
Penerapan Metode Drill and Practice Dalam Upaya Meningkatkan Hasil Belajar Pendidikan Agama
Authors: Huproni Huproni
Published: December 2020

This study aims to improve student learning outcomes through the use of drill and practice models in Islamic studies in class XII IPS 3 at SMAN 1 Pusakagara. This research is a descriptive qualitative research with a sample population of 36 students consisting of 21 male students and 15 female students, data obtained through interviews, tests, and observations. From the test data in the first cycle, the student learning outcomes who completed were 22 students with an average score of 69 and the highest score was 85, while the lowest score was around 45. In the second cycle, student learning outcomes who completed an increase even though the number was not so significant. Of the 36 students who are in the upper class, there are about 26 students and 10 students in the lower class, the highest score is 87 and the lowest score is 51 with a standard deviation of 9. By using the drill and practice learning model in Islamic studies in Class XII IPS 3 at SMAN 1 Pusakagara has improved student learning outcomes when compared to teachers who teach using the lecture method.
Konsep dan Penerapan Model Kebijakan Corporate Environmental Responsibility di Indonesia
Authors: Isnaini Syamsudin , Diamantina Amalia
Published: December 2020

The friction between economic interests and environmental interests has become a serious problem today. The friction between the two interests is evident in the activities of a company, therefore a company is given responsibility for the impact caused by its activities. This responsibility is “corporate social and environmental responsibility”. However, the term "Corporate Social Responsibility (CSR)" is often used in Indonesian society. The use of this term has a legal consequence, namely that the company's responsibility is only social responsibility, while environmental responsibility does not exist. Departing from these problems, this study will focus on discussing problems regarding the “Corporate Environmental Responsibility (CER)” policy model in Indonesia, particularly regarding the CER policy model, and the types of CER policies. This research is a normative juridical research with a statutory approach and a conceptual approach. The data used is secondary data in the form of laws and regulations and news about company and / or government programs in the field of environmental management. Based on the research results, it is known that the CER policy model clarifies and reinforces the regulation of corporate responsibility towards environmental aspects, CER policies can come from corporate initiatives or come from government initiatives.
Urgensi Pembentukan Lembaga Adat Urang Lom Guna Memberikan Perlindungan Suku Lom
Authors: Wirazilmustaan Wirazilmustaan , Robuwan Rahmat , Agustian Rio Armanda
Published: December 2020

Bangka Belitung Province have a community called a native population known as the Lom or Urang Lom. Legal recognition of the Urang Lom community in the formation of the Village Customary Institution where Urang Lom still lives is a very important part of the perspective of legal protection. The form of legal protection against the existence of Urang Lom is only limited to the recognition of a traditional institution called Mapur Customary Institution which is under the auspices of the Malay Customary Institution of Bangka. The formal and material legality problem in the formation of the Urang Lom Customary Institution in Gunung Muda and Gunung Pelawan Villages is related to the synergy of the Mapur Customary Institution that has been formed with the Village Customary Institutions based on the Village Law. Gunung Muda Village, and Gunung Pelawan Village made the formation of the Village Customary Institution be difficult because it clashed with the village territorial area.
Dasar-Dasar Pemikiran Perlindungan Hak Kekayaan Intelektual
Authors: Darwance Darwance , Yokotani Yokotani , Anggita Wenni
Published: December 2020

Basically, humans are born with different intellectual abilities in processing their thougths and produce somethingfrom that thought. Therefore, it is important to provide protection for the results of thought through the intellectual property rights regime. However, in practice there are still many cases where the intellectual property of a person or agroup or a legal entity is used without prior permission.  This juridical normative research examines fundamental thoughts for the protection of the results of one's thinking which is called intellectual property rights. There are several thoughts which become form the basis for protecting intellectual property rights; they are the natural right protection to reputation that has been built over a long time and quite high cost and also as a form of compensation and encouragement for people to create or find something.With the basic ideas behind the protection of IPR, the protection provided will be maximized, and the results of one's thinking will be more respected, both moral rights and economic rights
A PRÁTICA DA SÉRIE DE CASO COMO MÉTODO ANALÍTICO NA ABORDAGEM MISTA
Authors: Nascimento da Silva Carine , Kuhn Vieira Camila , De Lurdes Lauxen Sirlei , Cauduro Peranzoni Vaneza
Published: December 2020

A pesquisa cientifica, geralmente se insere no contexto humano como uma curiosidade dos porquês dos acontecimentos e se destaca por ser um dos processos de construção de conhecimento rigoroso, que é muito válido e confiável, que gera a ciência. Essa pesquisa é complexa e minuciosa que contextualiza uma série de metodologias que podem ser aplicadas em três abordagens diferentes, a quantitativa, a qualitativa e a conjugação das duas que é a pesquisa mista. Portanto, este trabalho teve por objetivo realizar uma revisão bibliográfica a respeito do método de série de casos em sua prática analítica na abordagem mista e sua utilização no meio cientifico. Realizou-se uma revisão bibliográfica, nas bases de dados do Google Acadêmico, EBSCO, Medline e PubMEd entre os meses de maio a agosto de 2019, buscando os critérios da temática.  A série de casos se mostrou uma ótima forma de alcançar o saber, principalmente quando se trata de buscas inovadoras e inexistentes. Além disso, ao utilizar múltiplas abordagens, como é característica da abordagem mista, consegue-se que haja uma contribuição mútua das potencialidades de cada uma delas, dispondo de respostas questionadas mais concretas aos problemas de pesquisa. Conclui-se assim, que os métodos mistos podem contribuir de forma significativa para futuras pesquisas cientificas, e através dessa abordagem, a série de casos é uma ótima tipo de pesquisa, para responder técnicas inovadoras de metodologia. Isso demostra a importância de realizar novas pesquisas de cunho bibliográfico e cientifico, sobre pratica de série de casos na abordagem mista.
钢结构长效防腐喷砂除锈工艺改进
Authors: 陈 锋
Published: December 2020

随着防腐材料、防腐工艺、防腐施工技术的发展，钢结构防腐的施工技术和施工要求更加严格，传统工艺的钢结构防腐已不能满足现代化工艺的要求。从防腐专业技术和安全管理的角度出发，鉴于矿业工程特殊的工作环境，为此，摸索出一套有异于传统工艺的施工方法。
建筑工程桩基检测中存在的问题与对策
Authors: 魏 偈
Published: December 2020

在多方面利好因素的影响下，使得我国社会综合国力得到了显著的提升，从而有效的推动了各个领域的发展壮大，尤其是建筑工程行业的发展速度更加的显著。在一个完整的建筑工程项目中，桩基结构的作用是非常重要的，其与整个工程结构的质量和施工的安全存在直接的关联。桩基检测工作在整个工程检测工作中的作用是非常巨大的，其对于保证施工质量能够起到积极的影响。在组织开展实际检测工作的时候，因为受到外界多方面因素的影响，所以往往会对桩基检测工作的实施形成诸多的困扰，这些困扰不仅会对桩基检测工作的有序开展产生限制，并且对于检测结果的准确性也会形成诸多的威胁。鉴于此，这篇文章主要围绕建筑工程桩基检测工作展开全面深入的研究分析，希望能够对我国建筑工程行业的持续健康发展有所帮助。
海区航标遥测遥控系统完善与优化研究
Authors: 刘 瑶舟
Published: December 2020

航标作为国家重要的航运设施，对于国家海域主权有着重要的意义。遥测系统是利用航标通信为海面测量、监控提供有效支撑，为了突破当前遥测遥控系统存在的瓶颈，需要对系统进行全面分析，对其系统加以完善，提高航标导航的能力。文章基于海区航标遥测遥控系统进行分析，针对其通信设计、终端等问题，采取有效的措施，帮助解决系统报文、遥测不经准的现象，完善系统，保障水域船舶航行的安全性。
钢管桩边坡加固技术及其应用探究
Authors: 顿 海山
Published: December 2020

在工程建设中边坡形式较为常见，如果由于因素干扰造成边坡失稳，很容易导致滑坡事故。钢管桩边坡加固技术不但适用范围广，而且施工便捷、稳固性高。文章将以钢管桩边坡加固施工工艺为研究对象，探索其具体应用，希望能够为工程实践提供有价值的参考。
建筑工程质量通病及工程质量管理措施探究
Authors: 朱 恩勇
Published: December 2020

建筑工程质量与企业生产和人们生活安全有很大关联，工程质量通病降低了工程质量，破坏了建筑工程的整体功能性，影响了施工单位的市场竞争力和建筑企业创收效益，在建筑工程施工过程中，要加大工程质量管理重视力度，加强工程质量管理工作成效,做到早发现早解决，总结管理经验教训，减少工程质量通病的产生，进而打造优质精良的建筑工程项目，有利于加快建筑工程事业良好健康发展的脚步。
道桥施工中混凝土施工技术应用
Authors: 邓 海望
Published: December 2020

对于整个工程的建设来说，混凝土建设工艺是非常重要的，也是整个建设工程的主体施工工艺，此项工艺的品质与整个工程的品质以及安全都是息息相关的额，多以，整体对混凝土施工工艺进行相应的管控和保证是非常重要的。在其建设施工的过程中，要对其中影响的因素进行全面的分析，并且对施工品质以及相关体系进行完善和保证。本文主要分析和研究了道桥施工中所存在的问题以及相应的混凝土施工技术管控措施。
Quantitative Differentiation of Renal Cell Carcinoma From Fat-Poor Angiomyolipoma and Between Renal Cell Carcinoma Subtypes by Using Three-Phase MDCT
Authors: Rongthong Sasiprapa , Pisutkawin Tanakorn , Phongkitkarun Sith
Published: December 2020

Background: Renal cell carcinoma (RCC) can be differentiated from angiomyolipoma by detection of macroscopic fat at multidetector computed tomography (MDCT). Measurement of enhancement at MDCT help classifying between RCC subtypes, which possibly predict tumor prognosis.

Objective: Retrospectively assess whether quantitative measurements (percentage enhancement ratio [PER] and absolute washout ratio [AWR]) of renal mass enhancement during three-phase MDCT help differentiating RCC from fat-poor angiomyolipoma and other RCC subtypes.

Methods: The retrospective review of the preoperative three-phase MDCT (unenhanced, corticomedullary, and early excretory phases) performed between January 2008 and July 2017, a total of 75 renal lesions (74 consecutive patients) were assessed for attenuation values in each phase. The enhancement values (PER and AWR) were compared by ANOVA tests. Cutoff analysis of enhancement values was performed to determine optimal threshold for each histologic subtype.

Results: The attenuation value of fat-poor angiomyolipoma was significantly higher than clear cell RCCs in unenhanced phase (P = .02). The PER of the clear cell RCCs was significantly lower than that of papillary RCCs, chromophobe RCCs, and fat-poor angiomyolipomas (P < .001). The AWR of the clear cell RCCs showed significantly greater than that of papillary RCCs and fat-poor angiomyolipoma (P < .001). The PER and AWR thresholds for differentiating RCCs from fat-poor angiomyolipoma were 93.0 and 31.6 with accuracy of 74.7% and 77.3%, respectively.

Conclusions: Quantitative measurement of enhancement (PER and AWR) might help differentiating RCCs from fat-poor angiomyolipoma, and differentiating clear cell RCCs from papillary RCCs.
A FESTIVAL AS A PEDAGOGICAL TOOL TO PROMOTE INCLUSION IN THE COMMUNITY AND IN SCHOOLS
Authors: Jeznik Katja , Skubic Ermenc Klara , Mažgon Jasna
Published: December 2020

The focus of education policies on greater equity and accessibility of education for all exposes an important difference between narrow and broad definitions of the concept of inclusion. The narrow definition is tied above all to the school context, where responsibility for the realisation of inclusion lies with pedagogical workers. The broad definition refers to an understanding of inclusion as the embracing of diversity as a positive value for the community, regardless of the institutional context in which we endeavour to achieve inclusion. The research discussed the inclusive educational practice of a special educational institution catering for individuals with intellectual disabilities. Using a sample of 139 participants at the international inclusive festival Play With Me, the attitudes towards inclusion and towards persons with special needs (a Likert scale was created) were researched. The results indicate that respondents generally had positive attitudes towards inclusion; there were differences between them, depending on the roles they undertook at the festival (mentors of students taking part in the festival and volunteers running various festival activities), the institutions they came from (special or mainstream educational institutions, associations, NGOs), and whether or not they had experience of individuals with special educational needs (SEN), either in their work or in their studies. Although a broad understanding of inclusive culture is present in the statements of respondents, it appears that both general and special teachers (in the role of mentors) still incline slightly more towards a narrow understanding of inclusion than volunteers do, which raises questions about pedagogical workers' conception of education. Keywords: inclusion understanding, intellectual disabilities, positive attitudes, special educational institution.
THE RELATIONSHIP BETWEEN TEACHERS’ EDUCATION AND THEIR SELF-PERCEIVED COMPETENCE FOR TEACHING HOME ECONOMICS
Authors: Kostanjevec Stojan , Lovšin Kozina Francka , Erjavšek Martina
Published: December 2020

Relevant teacher qualifications that include specialist knowledge and knowledge in didactics significantly influence the level of achievement of education goals during the teaching process. Teacher's perception of their own professional competence to teach may depend on their qualification which is linked to the education obtained. The purpose of the research was to find out how teachers who teach Home Economics in Slovenian elementary schools estimate their competence to teach Home Economics contents, in reference to their formal education. 89 teachers of 5th and 6th grade Home Economics participated in the research. They were classified according to their formal education, either in the group with completed Home Economics studies (relevant education) or in the group without these studies (irrelevant education). A questionnaire was developed for the teachers to assess their own teaching competence. The obtained data was analysed with descriptive and inferential statistical methods. Results indicated that teachers with completed home economics studies who teach Home Economics feel more competent to teach Home Economics contents than teachers without completed relevant studies. Differences in their perceptions exist in all four Home Economics modules, i.e. economics, textile and clothing, living and environment, food and nutrition. This leads to the conclusion that relevant teacher education is important for teaching Home Economics in all specialist areas of home economics education. As regards providing quality education process and achieving Home Economics education goals, the results indicate that relevant qualifications of teachers should be ensured. Teachers with irrelevant education should be provided with additional professional training.
Key words: teachers' education, teachers' competencies, Home Economics, Home Economics teachers, home economics education.
THE RELIABILITY OF AN INSTRUMENT TO MEASURE TEACHER KNOWLEDGE FROM THE PERSPECTIVE OF LEARNERS IN THE CONTEXT OF PIBID
Authors: Nogueira Keysy S. C. , Fernandez Carmen
Published: December 2020

This research sought to analyze the reliability of an instrument to measure teacher knowledge of a group of pre-service chemistry teachers participating in the Institutional Program for Scholarships for Beginner Teachers in Brazil (PIBID).. Thus, it was analyzed the evaluation of a group of students about the Pedagogical Content Knowledge (PCK) of five pre-service chemistry teachers from the program. Accordingly, an instrument containing 28 statements and an open question was applied to a group of 70 students from a public school to whom the pre-service teachers had applied their didactic proposals. The purpose of the instrument was to measure the perception of the students' about the components of the teacher knowledge (Subject Matter Knowledge - SMK, Instructional Representation and Strategies - IRS, Instructional Objective and Context - IOC and Knowledge of Students’ Understanding - KSU) of the pre-service teachers. The results of the analysis revealed that the instrument about teacher’s knowledge has a high reliability based on the alpha Cronbach values. The results of the alpha coefficient for the pre-service teachers were all above 0.9 suggesting that the instrument is reliable and has consistent measurements. Regarding to the exploratory analysis, the main scale in the PCK evaluation of the undergraduates was four which means that the students consider that the aspects related to the SMK, IRS, IOC and KSU are frequently present in the classes of the future teachers. Keywords: instrument reliability, PIBID, redox reactions, teaching knowledge, PCK.
Qualitative Analysis of the Determinants of Malnutrition Among Children Under-five in Households in the Mayo-Danay Department, Cameroon
Authors: Gaël Bita André Izacar , Chukuwchindun Benjamin Azike , Biwole Omgba Thomas Eddy , Agbornkwai Agbor Nyenty , Eyong Justin Bienvenu , Sanou Martin Sobze
Published: December 2020

The Far North region has the highest rate of chronic malnutrition (35.9%) ahead of East (35.4%); North (30.6%) and Adamawa (28.7%). The study aimed to identify contextual factors of child malnutrition in line with UNICEF’s causal pattern of malnutrition (2013). This was a qualitative study. Multiple case sampling of social micro-units was used. Focus-groups; face-to-face interviews and observations were organized. Seguin method was used for data analysis (2010). Fifty people participated in the study. Mayo-danay is a landlocked area, where the lack of food processing and food conservation infrastructure promotes early and low-cost liquidation of food products. A situation that exposes families to famine and poverty a few months after the harvest. The influx of internally displaced persons (IDPs); insecurity due to terrorism has weakened cross-border trade. The household size is up to 10 members, that did not allow children to eat at their convenience, and in a diverse way. The Christian head of households did not systematically contribute to the food ration, unlike the Muslims. Fish, agricultural and livestock products are more for sale than for consumption in the household. There are frequent shortages of food supplements for the management of malnutrition in health training. The causes of malnutrition in Mayo-Danay were multifactorial. Strategies to fight against malnutrition must take into account the integrated approach to local and sustainable development.
The Development of E-Module to Improve Learning Results Introduction to Accounting I
Authors: Damanik Togi Martua , Hutasuhut Saidun , Fitrawaty Fitrawaty
Published: December 2020

To realize the success of improving education, efforts must be made from various sides, namely paying attention to all components that play an important role such as improving the quality of lecturers, curriculum, facilities and infrastructure, management and community participation. E-module with the sigil application really helps students in lectures because the tutorial content facility supports both descriptions in text, images, and videos so that students have an interest, are able to understand and review learning materials properly and motivate them to study independently. The objectives of this study are: 1) to produce problem solving-based e-modules that are suitable for use in learning, 2) to determine the effectiveness of e-modules developed in improving learning outcomes. Introduction to accounting I. This type of development research uses the Borg & Gahl model with the Dick n Carey development model. The results showed; (1) The instructional media expert test is at very feasible criteria (80.26%), (2) the learning design expert test is in the appropriate criteria (75%), (3) the material expert test is at very feasible criteria (92.5 %), (4) small group trials are in very feasible criteria (84.16%) (5) Limited field trials are in very feasible criteria (81.79%). Based on the results of the feasibility assessment of the developed problem solving-based e-module with the percentage of the average score of the overall variable score of 82.74%, it is included in the “very feasible” category, meaning that the developed e-module is proven to be feasible for use.
Hypobaric Decompression and White Matter Hyperintensities: An Evaluation of the NATO Standard
Authors: Ottestad William , Hansen Tor Are , Ksin Jan Ivar
Published: December 2020

INTRODUCTION: In their seminal work, McGuire and colleagues reported an increased incidence of white matter hyperintensities (WMH) in a cohort of U2 pilots and hypobaric chamber personnel. WMH burden was higher in U2 pilots with previous reports of decompression sickness (DCS),
and McGuire's reports have raised concerns regarding adverse outcomes in the aftermath of hypobaric exposures. Accordingly, a NATO working group has recently revised its standard recommendations regarding hypobaric exposures, including measures to mitigate the risk of WMH. Mandatory recovery
time for up to 72 h between repeated exposures has been suggested on the basis of experimental evidence. However, we argue that the evidence is scarce which supports restricting repeated exposures to mitigate WMH. It is plausible that WMH is correlated with DCS and emphasis should be made
on limiting the duration of exposures rather than restricting short and repeated exposures. The profiles in the NATO recommendations are meant to mitigate the risk of DCS. Still, they will potentially expose NATO Air Force and Special Operations personnel to flight profiles that can give rise
to DCS incidence above 35%. Awaiting reliable data, we recommend limiting the duration of exposures and allowing for short repeated exposures.Ottestad W, Hansen TA, Ksin JI. Hypobaric decompression and white matter hyperintensities: an evaluation of the NATO standard. Aerosp
Med Hum Perform. 2021; 92(1):3942.
ANALISIS KUALITAS PELAYANAN TERHADAP LOYALITAS NASABAH MELALUI KEPUASAN PADA KOPERASI KREDIT PINTU AIR CABANG MAKASSAR
Authors: Nur Andi Musfirawati , Ali Ardiansyah
Published: December 2020

Peningkatan jumlah koperasi yang ada di kota Makassar menunjukan perkembangan yang signifikan, dimana hal ini akan sangat bergantung pada kualitas pelayanan yang mereka berikan kepada nasabah. Pada akhirnya pelayanan yang kurang memuaskan akan berdampak pada loyalitas nasabah atau bahkan beralih ke jasa layanan lainnya yang lebih baik. Masalah dalam penelitian ini adalah performa layanan yang diberikan kepada nasabah dalam bertransaksi di Koperasi Kredit Pintu Air Cabang Makassar, dimana pelayanan cenderung kurang memuaskan bagi sebagian pelanggan mereka. Adapun tujuan dari penelitian ini adalah untuk menganalisis bagaimana gambaran kualitas pelayanan terhadap loyalitas nasabah melalui kepuasan pada Koperasi Kredit pintu air cabang Makassar. Jenis  penelitian yang digunakan dalam penelitian ini adalah Jenis penelitian kuantitatif dengan pendekatan deskriptif. Metode pengumpulan data menggunakan observasi partisipan, kuisoner dan telaah dokumen, di mana analisis data menggunakan path analysis untuk mengetahui hubungan antar variabel. Dari hasil penelitian, diperoleh bahwa kualitas pelayanan yang di berikan kepada nasabah tidak berpengaruh signifikan terhadap tingkat loyalitas nasabah ketika bertransaksi, akan tetapi loyalitas nasabah dapat berpengaruh signifikan terhadap kualitas pelayanan jika kepuasan nasabah terpenuhi.
La construcción de proyectos migratorios. Un estudio a partir de casos de migrantes tarijeños y tarijeñas con destino al Noroeste argentino
Authors: Ataide Soraya
Published: December 2020

The present article examines the construction of the migration project of immigrants from rural areas in the department of Tarija, Bolivia, whose destination is the agricultural labor market in the Northwest of Argentina. This paper aims to analyze the impact of push and pull factors on the construction of male and female migration projects. To achieve this objective, an ethnographic methodological strategy was used based on in-depth interviews.
Conceptual approaches to forming a development strategy of the tax system of Ukraine
Authors:   SESE “The Academy of Financial Management”, SOKOLOVSKA Alla
Published: December 2020

Tax strategy as a general plan for reforming the tax system in the medium term, defining ways to achieve goals and objectives of the reform, introduces elements of predictability in the activities of economic agents, facilitates its planning, protects against chaotic, unreasoned changes in tax legislation, provides to changes of coherence, sequence, transparency. Therefore, its development and implementation is an important element of strategic public administration, which has not been used in Ukraine in recent years. Given this, the purpose of the article is to reveal the conceptual foundations of the formation of a strategy for the development of the tax system of Ukraine. The article substantiates the advantages of subordinating the development of the tax system of Ukraine in the medium term to ensuring smart, sustainable and inclusive economic growth. Five strategic priorities have been identified for the implementation of tax reform aimed at achieving this goal: reducing income and wealth inequality; increasing the fairness of taxation; stimulating investment in innovation and social capital; greening of the tax system; increasing its fiscal efficiency and productivity by improving tax administration, increasing the capacity of tax authorities. For each of the priorities, possible measures and steps necessary for their implementation are proposed. The necessity of determining the expected results and performance indicators, on the basis of which the strategy implementation will be monitored and evaluated, has been substantiated. It has been established that the development of a strategy should begin with defining a system of restrictions generated by global, macroeconomic, institutional, political, and behavioral factors, and choosing a scenario for reforming the tax system. The general approaches to formation of structure of strategy, its purpose and strategic priorities are defined (should correspond to interests of all society, providing the decision of the important problems connected with inequality and poverty, safety of an environment and preservation of its diversity, creation of equal conditions of competition for business entities), requirements for the choice of measures and steps to ensure their implementation (compliance with the goal and priorities; realism; mutual coherence, consistency; systemacity (combination of changes in the structure of taxes and their elements with changes in tax administration and activities of institutions that ensure tax compliance). The necessity of introduction of monitoring and annual evaluation the effectiveness of the strategy implementation, as well as publication of reports on its implementation is substantiated.