bluuebunny/crossref_metadata_2025 huggingface dataset:
Erlotinib-associated interstitial pneumonitis with successful readministration
Authors: Tungjitviboonkun Songphol , Bumrungratanayos Naharuthai , Jitwimungsanon Jedsadakorn
Published: July 2023

Introduction

Erlotinib is the main stay treatment of non-small cell lung cancer (NSCLC) in recent years. Though, interstitial lung disease following erlotinib use is rarely develop, it is a fatal adverse event if not immediately treat.

Case Report

We report the first case of erlotinib-induced interstitial pneumonitis with successful readministration. A Thai 64-year-old male patient with NSCLC, information includes patient presentation, laboratory findings, chest x-ray, computed tomography (CT) of chest, corticosteroid dose and duration.

Management & Outcome

The patient readministrated erlotinib after developed interstitial pneumonitis 3 weeks without developing second adverse event. Evaluation of disease after 2 months of treatment is stable disease per RECIST v1.1.

Discussion

We assumed that the mechanism for interstitial pneumonitis are diverse and some mechanism is not related with drug directly but rather transient condition and the drug can be readministrated without developing second adverse event. This could lead to change in practice of erlotinib readministration in the future.
Implementation and maintenance of an enhanced pulmonary rehabilitation program in a single centre: An implementation study
Authors: van der Braak Kim , Wald Joshua , Tansey Catherine M , Paes Thais , Sedeno Maria , Selzler Anne-Marie , Stickland Michael K , Bourbeau Jean , Janaudis-Ferreira Tania
Published: July 2023

Background

Pulmonary rehabilitation (PR) has major benefits for patients with chronic obstructive pulmonary disease (COPD). An enhanced PR program was developed with a self-management education intervention. The objective of our study was to evaluate the implementation of the enhanced PR program into a single centre.

Methods

Pre-post implementation study consisted of two evaluation periods: immediately after implementation and 18 months later. Guided by the RE-AIM framework, outcomes included: Reach, Effectiveness, Adoption, Implementation and Maintenance .

Results

Reach: 70–75% of referred patients agreed to a PR program ( n = 26). Effectiveness: Clinically important improvements occurred in some patients in functional exercise capacity (64% of the patients achieved clinical important difference in 6-min walk test in the first evaluation period and 44% in the second evaluation period), knowledge, functional status, and self-efficacy in both evaluation periods. Adoption: All healthcare professionals (HCPs) involved in PR ( n = 8) participated. Implementation: Fidelity for the group education sessions ranged from 76 to 95% (first evaluation) and from 82 to 88% (second evaluation). Maintenance: The program was sustained over 18 months with minor changes. Patients and HCPs were highly satisfied with the program.

Conclusions

The enhanced PR program was accepted by patients and HCPs and was implemented and maintained at a single expert center with good implementation fidelity.
Tailored Music Listening in Persons With Dementia: A Feasibility Randomized Clinical Trial
Authors: Petrovsky Darina V. , Bradt Joke , McPhillips Miranda V. , Sefcik Justine S. , Gitlin Laura N. , Hodgson Nancy A.
Published: July 2023

Introduction: This study examined the feasibility, acceptability, and preliminary efficacy of tailored music listening intervention on sleep disturbances in older adults with dementia and their caregivers. Methods: We randomly assigned 33 older adults with dementia (mean age 71.7 [SD: 7.1], 72.7% female, 81.8% African American/Black) and their caregivers (mean age 58.4 [SD: 16.7], 72.7% female, 84.8% African American/Black) to a wait-list control or intervention group (NCT04157244). Results: The music intervention was feasible as evidenced by high study measure completion and retention rates (>90%). Recruitment was stopped prematurely due to the COVID-19 pandemic. We found mixed acceptability results from the survey and qualitative interviews with the participants. Both groups improved on objective sleep outcomes of sleep latency and wake sleep after onset. We found a small effect size for sleep duration post-intervention. Discussion: The findings provide preliminary evidence for the feasibility of a tailored music intervention and identified ways to improve its acceptability.
Mechanism and application of halogenation–dehalogenation in the development of pitch-based carbon fiber: A review
Authors: Liu Jinchang , Liu Qin , An Xiaoya , Wang Tong , Liang Dingcheng , Xie Qiang
Published: July 2023

Pitch-based carbon fiber, as one of the important engineering materials, has been widely used in aerospace, defense, sports, and other fields. In the long production process of pitch-based carbon fiber, the property of pitch precursor is significant for the mechanical performance of obtained carbon fiber. Thus, it is crucial to improve the property of pitch precursor by efficient means. Halogenation–dehalogenation is a newly developed method for the controllable synthesis of a pitch precursor from the molecular dimension, including fluorination–defluorination, chlorination–dechlorination, and bromination–debromination. This work reviewed the mechanism and application, as well as the advantages and disadvantages of each halogenation–dehalogenation method.
Cultural adaptation of the revised Basel Instrument for Rationing of Care to the Turkish context: a study of validity and reliability
Authors: Yürümezoğlu Havva Arslan , Schubert Maria , Sarıoğlu Emine , Kocaman Gülseren
Published: July 2023

Background:

Studies have shown that nurses do not complete one or more necessary nursing care elements in their last shift due to lack of time. The Basel Extent of Rationing Nursing Care (BERNCA) instrument is one of the most used scales to measure the rationing of nursing care.

Aim:

This study is aimed to culturally adapt the revised BERNCA (BERNCA-R) instrument to the Turkish language and to test its validity and reliability.

Methods:

A cross-sectional and methodological study was used. The instrument was adapted in three stages: translation and adaptation, content validity testing and validity and reliability. Data were obtained from 350 nurses working in two public acute care hospitals in Turkey, between September 2019 and January 2020. The descriptive statistics, content validity index, exploratory and confirmatory factor analyses, Cronbach’s α, Guttman split-half and inter-item reliability analyses were performed for the analysis of the data.

Results:

The Turkish version of the BERNCA-R instrument with a 27-item and three-subscales (monitoring, daily care and needs and psychosocial care) structure was found to have acceptable and good fit indices.

Conclusion:

The Turkish version of the BERNCA-R instrument is valid and reliable tool to measure rationing of nursing care.
Speeding up the transition to a more sustainable food system: New insights into the links in a system of practices
Authors: Innocent Morgane , Guillemot Samuel , Gabriel Patrick , Tamaro Annick
Published: July 2023

More sustainable food choices are part of a complex system that combines practices, which themselves are interconnected in a network of elements made up of competences, meanings and material devices. This article proposes an innovative method for studying this system through a non-deductive quantitative approach. The research adds to the corpus of the ‘theory of practices’ by defining the concepts of ‘central’ practices (i.e. connected to many elements of the system, such as the practice of buying and cooking sustainable products in the sustainable food system) and ‘peripheral’ practices (i.e. connected in a lesser extent to other elements of the system, such as the practices of anti-waste, growing your own food and the consumption of plant proteins). It also highlights the ‘connector’ role between the practices of certain elements. Finally, based on the current structure of the system of sustainable food practices, the article makes several propositions for speeding up change.
The Impact of Managing Diversity on Building the Smart City A Comparison of Smart City Strategies: Cases From Europe, America, and Asia
Authors: Demirel Demokaan
Published: July 2023

The use of ICT to optimize urban processes, activities, efficiency and effectiveness of services turns cities into smart. Smart cities make it necessary to plan, monitor and analyze the city, except for the routine functions of the city. The study examined what smart city research projects are in five representative smart cities (London, New York, Singapore, Barcelona, and Istanbul) and whether there are similarities or differences in background assumptions. The literature used has a global reach; cities around the world have been chosen for comparison. By evaluating the existing literature, it has been evaluated that smart cities are the most successful and the weakest issues. Despite the centrality of New York and London’s smart city policies; they are fairly superior in economic competition. Public participation in smart city projects is already weak in Singapore and Istanbul. Barcelona has a more participatory policy than other cities, but it needs to develop a smart governance perspective. The study concludes with how the smart city ideology achieves its goals. The study adds value to smart city research by a critical look at the subject. Combining the results of practical smart city initiatives, it concludes the practicality and usefulness of smart city development.
Using Nostalgic Emotions to Revive Indian Ethnic Drinks Market: Competitive Strategy at Paper Boat
Authors: Garg Priyanka , Farooqi Rahela , Garg Yakshi , Kala Devkant , Singh Sumanjeet
Published: July 2023

Amidst the intensive cola war in the Indian market, Hector Beverages Private Limited introduced ethnic drink as a competitive strategy to attract Indian consumers. This move aims to attract Indian consumers by not only offering health benefits and nutritional value but also providing a sense of connection to the past and emotional satisfaction through old memories. Paper Boat, an ethnic and nostalgic beverage brand of Hector Beverages, has disrupted the Indian beverage industry, challenging market leaders to provide innovative and nutritional drinks. The case study highlights Paper Boat’s innovative value proposition and nostalgia marketing campaigns, while also examining the competitive strategies of major players in the Indian beverage industry. The case study also raises important questions that Hector Beverages must consider remaining relevant in a changing market and retaining its competitive advantage.
Pragmatic fidelity measurement in youth service settings
Authors: Wang Lu , Stoll Samantha J. , Eddy Christopher J. , Hurley Sarah , Sisson Jocelyn , Thompson Nicholas , Raftery-Helmer Jacquelyn N. , Ablon J. Stuart , Pollastri Alisha R.
Published: July 2023

Background

Fidelity measurement is critical for developing, evaluating, and implementing evidence-based treatments (EBTs). However, traditional fidelity measurement tools are often not feasible for community-based settings. We developed a short fidelity rating form for the Collaborative Problem Solving (CPS) approach from an existing manualized coding system that requires extensive training. We examined the reliability and accuracy of this short form when completed by trained observers, untrained observers, and self-reporting providers to evaluate multiple options for reducing barriers to fidelity measurement in community-based settings.

Methods

Community-based treatment providers submitted recordings of youth service sessions in which they did, or did not, use CPS. For 60 recordings, we compared short-form fidelity ratings assigned by trained observers and untrained observers to those provided by trained observers on the manualized coding system. For 141 recordings, we compared providers’ self-reported fidelity on the short form to ratings provided by trained observers on the manualized coding system and examined providers’ accuracy as a function of their global fidelity.

Results & Conclusions:

The short form was reliable and accurate for trained observers. An assigned global integrity score and a calculated average of component scores on the short form, but not component scores themselves, were reliable and accurate for observers who had CPS expertise but no specific training on rating CPS fidelity. When providers self-reported fidelity on the short form, their global integrity score was a reliable estimate of their CPS integrity; however, providers with better CPS fidelity were most accurate in their self-reports. We discuss the costs and benefits of these more pragmatic fidelity measurement options in community-based settings.
Barriers and Facilitators to Accessing Sexual and Reproductive Health Services Among Transgender People: A Meta-Synthesis
Authors: Saadat Mina , Keramat Afsaneh , Jahanfar Shayesteh , Nazari Ali Mohammad , Ranjbar Hadi , Motaghi Zahra
Published: July 2023

The availability and accessibility of sexual and reproductive health (SRH) services for transgender individuals are crucial. This population is deprived of health care due to rejection, stigma, gender-based discrimination, confidentiality, and violence. This review attempts to provide readers with an account of the fundamental problems that the transgender population faces regarding experiences of SRH. This meta-synthesis review applied the Social–Ecological Model (SEM) to address trans individuals’ SRH factors. The databases were searched using “SRH” and “transgender” keywords. Fifty studies were finally selected. All studies were qualitative, including 36 semi-structured/ in-depth interviews, two focus group studies, and 12 interviews and focus group studies. The Social–Ecological Model application illustrates the impact of individual, interpersonal, institutional, and social factors on the condition of SRH among transgender individuals. This meta-synthesis reinforces multiple levels of factors that influence the SRH of transgender individuals. These include limited information, lack of awareness, low socioeconomic status, stigma and discrimination, and social deprivation. Interventions are urgently needed to provide better sexual and reproductive well-being for transgender individuals.
Debate: differences and similarities between tension-type headache and migraine
Authors: Onan Dilara , Younis Samaira , Wellsgatnik William David , Farham Fatemeh , Andruškevičius Saulius , Abashidze Ana , Jusupova Asel , Romanenko Yuriy , Grosu Oxana , Moldokulova Meerimgul Zamirbekovna , Mursalova Ulkar , Saidkhodjaeva Saida , Martelletti Paolo , Ashina Sait
Published: July 2023

Tension-type headache (TTH) and migraine are two common primary headaches distinguished by clinical characteristics according to the 3rd edition of the International Classification of Headache Disorders. Migraine is identified by specific features such as being more prevalent in females, being aggravated by physical activity, certain genetic factors, having photophobia, phonophobia, nausea, vomiting, or aura, and responding to specific drugs. Nonetheless, TTH and migraine share some common characteristics, such as onset occurring in the 20 s, and being triggered by psychological factors like stress, moderate pain severity, and mild nausea in chronic TTH. Both conditions involve the trigeminovascular system in their pathophysiology. However, distinguishing between TTH and migraine in clinical practice, research, and epidemiological studies can be challenging, as there is a lack of specific diagnostic tests and biomarkers. Moreover, both conditions may coexist, further complicating the diagnostic process. This review aims to explore the similarities and differences in the pathophysiology, epidemiology, burden and disability, comorbidities, and responses to pharmacological and non-pharmacological treatments of TTH and migraine. The review also discusses future research directions to address the diagnostic challenges and improve the understanding and management of these conditions.

Graphical Abstract
Is vitamin D supplementation program in Iranian schools effective in reducing adolescent depressive symptoms? Cost effectiveness study
Authors: Jasemi Seyed Vahid , Zandieh Zhale , Zandieh Narges , Hemami Mohsen Rezaei , Darvishi Ali , Abdollahi Zahra , Heshmat Ramin
Published: July 2023

Purpose

We aimed to assess the cost-effectiveness of the vitamin D supplementation program in Iranian adolescents reducing adolescent depressive Symptoms.

Methods

In the current cost-effectiveness analysis, the viewpoint of Iran’s Ministry of Health was selected. The target population was 1,519,762 Iranian high school students (733,657 girls and 786,105 boys). The total costs of the vitamin D supplementations program were based on the reports of the Nutrition Improvement Office of Iran’s Ministry of Health and were adjusted to 2018. The variable of Quality-Adjusted Life Years (QALYs) was considered a suitable variable for estimating the effectiveness of vitamin D supplementation. We chose one year as the time horizon. A decision tree model was constructed in TreeAge Pro. The results of the cost-effectiveness analysis were reported in term of the Incremental Cost-Effectiveness Ratio (ICER).

Results

The results of our study showed that the estimated cost per QALY gained of the vitamin D supplementation program is equal to 1528.6676 $, which indicates that vitamin D supplementation in adolescents(11-18Y) is a cost-effective and a dominant strategy in preventing depression through the cost-saving and QALYs increment compared to the no intervention. Sensitivity analysis showed that the possible variations in vitamin D supplement costs could not alter the results, and vitamin D supplementation may be a predominant and cost-effective strategy to prevent adulthood depression with a 100% probability.

Conclusion

The national program of vitamin D supplementation among Iranian adolescents was a cost-efficient strategy reducing adolescent depressive Symptoms through the cost-saving and QALYs increment compared to the no intervention.
Community perspectives and experiences of quality maternal and newborn care in East New Britain, Papua New Guinea
Authors: Wilson Alyce N. , Melepia Pele , Suruka Rose , Hezeri Priscah , Kabiu Dukduk , Babona Delly , Wapi Pinip , Morgan Alison , Vogel Joshua P. , Beeson James , Morgan Christopher , Kelly-Hanku Angela , Scoullar Michelle J. L. , Nosi Somu , Vallely Lisa M. , Kennedy Elissa , Bohren Meghan A. , Homer Caroline S. E.
Published: July 2023

Background

Quality maternal and newborn care is essential for improving the health of mothers and babies. Low- and middle-income countries, such as Papua New Guinea (PNG), face many barriers to achieving quality care for all. Efforts to improve the quality of maternal and newborn care must involve community in the design, implementation, and evaluation of initiatives to ensure that interventions are appropriate and relevant for the target community. We aimed to describe community members’ perspectives and experiences of maternal and newborn care, and their ideas for improvement in one province, East New Britain, in PNG.

Methods

We undertook a qualitative descriptive study in partnership with and alongside five local health facilities, health care workers and community members, using a Partnership Defined Quality Approach. We conducted ten focus group discussions with 68 community members (identified through church, market and other community-based groups) in East New Britain PNG to explore perspectives and experiences of maternal and newborn care, identify enablers and barriers to quality care and interventions to improve care. Discussions were transcribed verbatim. A mixed inductive and deductive analysis was conducted including application of the World Health Organisation (WHO) Quality Maternal and Newborn Care framework.

Results

Using the WHO framework, we present the findings in accordance with the five experience of care domains. We found that the community reported multiple challenges in accessing care and facilities were described as under-staffed and under resourced. Community members emphasised the importance of good communication and competent, caring and respectful healthcare workers. Both women and men expressed a strong desire for companionship during labor and birth. Several changes were suggested by the community that could immediately improve the quality of care.

Conclusions

Community perspectives and experiences are critical for informing effective and sustainable interventions to improve the quality of maternal and newborn care and increasing facility-based births in PNG. A greater understanding of the care experience as a key component of quality care is needed and any quality improvement initiatives must include the user experience as a key outcome measure.
Green approach for the synthesis of ZnO nanoparticles using Cymbopogon citratus aqueous leaf extract: characterization and evaluation of their biological activities
Authors: Abdelbaky Ahmed S. , Mohamed Abir M. H. A. , Sharaky Marwa , Mohamed Nira A. , Diab Yasser M.
Published: July 2023

Background

The green synthesis of metal and metal oxide nanoparticles (NPs), notably from plants, has attracted increasing attention in recent years. Although the increased popularity use of Cymbopogon citratus as a therapeutic substance, to date, there has not been any research on the chemistry of C. citratus aqueous leaf extract (ALE) or synthesis of ZnO NPs utilizing an extract from it. The ecologically safe ALE of C. citratus was employed in this study as a bio-reducing and capping agent to synthesize ZnO NPs.

Results

The novelty of the current study is the investigation of the antioxidant, anti-inflammatory, anti-microbial, and cytotoxic potencies of biosynthesized ZnO NPs utilizing C. citratus ALE. Zinc acetate dihydrate was used as the precursor and the leaf extract serves as the reducing agent. ZnO NPs from ALE of C. citratus were characterized by the spherical in form by using high-resolution transmission electron microscopy (HR-TEM) and the Scherrer formula was used to calculate the size of the crystalline structure. The presence of numerous functional groups in both the ALE and the NPs is confirmed by FTIR analysis. The highest absorption peak is observed at 370 nm. The stability and particle size of the biosynthesized ZnO NPs are demonstrated by dynamic light scattering (DLS) analysis. The biosynthesized ZnO NPs exhibited excellent antioxidant activity with an IC50 value of 45.67 ± 0.1 μg/mL and exerted interesting anti-inflammatory activity (98.1% ± 0.04) when compared to the standard indomethacin (92.1% ± 0.07) at 1 mg/mL. They also showed anti-microbial activity for both bacterial and fungal which growth rates for both significantly decreased with the increase in ZnO NPs concentration compared to the control. The anticancer activity of biosynthesized ZnO NPs and C. citratus ALE was in vitro tested against seven human cancer cell lines (HCCL) (i.e. H1299, MDA-MB-468, HNO97, HEK, HCT116, HuH7, and HEPG2) compared to normal cells (HSF) using the sulforhodamine-B (SRB) assay. More interestingly, the biosynthesized ZnO NPs displayed remarkable selective cytotoxicity against all tested cancer cell lines without any effect on normal cells. In contrast, the cancer cell lines were not affected by the ALE of C. citratus at any concentrations tested.

Conclusions

All the findings confirm that the ZnO NPs biosynthesized in the current work are promising candidates for a variety of biological activities, and as a result, they can be helpful to the medical sector, environmental and agricultural applications.

Graphical Abstract
An unknown source of Micrococcus luteus bacteremia
Authors: Pederson Addie , R. Boone Coleman  , Mary Irving
Published: July 2023

Micrococcus luteus is a common organism in the human skin flora. It is an uncommon cause of pathogenic bloodstream infections, which occur mostly in immunocompromised patients. We report the clinical course of an 82-year-old man who underwent complex management of multiple diverticular abscesses and had three serial positive blood cultures for M. luteus. Despite treatment with vancomycin, the patient ultimately died due to septicemia secondary to mixed gastrointestinal flora and M. luteus. A source this infection was never definitely identified.
Clients’ perspectives on the utilization of reproductive, maternal, neonatal, and child health services in primary health centers during COVID-19 pandemic in 10 States of Nigeria: A cross-sectional study
Authors: Adelekan Babatunde , Goldson Erika , Ntoimo Lorretta Favour C. , Adonri Osaretin , Aliyu Yakubu , Onoja Matthew , Araoyinbo Idowu , Anakhuekha Emilene , Mueller Ulla , Ekwere Eno-Obong , Inedu Micheal , Moruf Olayinka , Swomen George , Igboin Brian , Okonofua Friday E.
Published: July 2023

Background

Reports from various parts of the world suggest that the COVID-19 pandemic may have severe adverse effects on the delivery and uptake of reproductive health, maternal, neonatal, and child health (RMNCH) services. The objective of the study was to explore women’s experiences with utilization of RMNCH services during the COVID-19 pandemic in Nigeria, and to elicit their perceptions on ways to sustain effective service delivery during the pandemic.

Methods

A cross-sectional survey of 2930 women using primary health care facilities for antenatal, delivery, postnatal, and child care services before and after the onset of the pandemic in 10 States of Nigeria were interviewed with a semi-structured questionnaire. Data were collected on women’s socio-demographic characteristics and pregnancy histories, the services they sought before and after the pandemic, the challenges they faced in accessing the services, their use of alternative sources of health care, and their recommendations on ways to sustain RMNCH service delivery during the pandemic. The data were analyzed with descriptive statistics, and multivariable logistic regression using SPSS 20.0. All the statistical analyses were two-tailed with a 95% confidence interval, and the p-value was set at 0.05.

Results

The logistic regression results showed that women were at least 56% more likely to report that they used family planning, antenatal, and delivery services before the pandemic than after the pandemic started, but 38% less likely to report use of postnatal services. The experience of difficulty accessing RMNCH services was 23% more likely after the pandemic started than before the pandemic. Three categories of recommendations made by the respondents on measures to sustain RMNCH delivery during the pandemic included 1) facility improvement, and staff recruitment and re-training; 2) free and readily accessible PHC services, and 3) the provision of social safety nets including transportation and palliatives.

Conclusion

We conclude that the COVID-19 pandemic limited women’s access to antenatal, delivery, and childcare services offered in PHCs in Nigeria. Addressing the recommendations and the concerns raised by women will help to sustain the delivery of RMNCH services during the COVID-19 pandemic and future epidemics or health emergencies in Nigeria.
Global long-term trends and spatial cluster analysis of pancreatic cancer incidence and mortality over a 30-year period using the global burden of disease study 2019 data
Authors: Amini Maedeh , Azizmohammad Looha Mehdi , Rahimi Pordanjani Sajjad , Asadzadeh Aghdaei Hamid , Pourhoseingholi Mohamad Amin
Published: July 2023

Introduction

Pancreatic cancer (PC) is one of the most fatal malignancies, and its incidence and mortality rates are growing annually throughout the world. In this research, we aimed to investigate the time trends and identify the spatial clusters of incidence and mortality on a global scale over the last 30 years, using the Global Burden of Disease (GBD) study 2019 data.

Methods

Age-standardized incidence and mortality data due to PC were extracted from the GBD study, which was carried out from 1990 to 2019. A Joinpoint regression analysis was utilized to examine trends in the incidence and mortality of PC over the past three decades. As such, spatial analyses were undertaken to detect the spatial distribution and clustering of the metrics globally.

Results

It was observed that both the incidence and mortality rates were higher in males than in females worldwide. The global mortality and incidence rates significantly increased by 0.8% per year over the time of follow-up period (p<0.05). By spatial cluster analysis for mortality, European and North African countries, as well as Greenland were explored as hot spots; while South African and Southeast Asian countries were explored as cold spots. Regarding incidence, hot spots were found in European countries, Southern America, and Greenland; whilst cold spots were determined in Southern Africa and Madagascar.

Conclusions

Collectively, the temporal trends disclosed a gradual rise in PC incidence and mortality rates over the period 1990–2019, reflecting the global health concern. We further found geographical variations in the patterns and identified high- and low-risk areas for incidence and mortality. These findings facilitate the design and implementation of more resource-efficient and geographically targeted treatments. Given the results of the current study, a practical approach to minimizing the future PC burden involves planned population-wide interventions, as well as primary prevention through healthier lifestyles.
Influence of family parenting style on the formation of eating behaviors and habits in preschool children: The mediating role of quality of life and nutritional knowledge
Authors: Ningning Wang , Wenguang Cheng
Published: July 2023

To provide empirical support for understanding the effects of different family parenting styles on the development of preschool children’s eating habits and to promote healthy child development. Using a randomized whole-group sampling method, full-time public kindergartens in three regions of China were selected as the study population of preschool children, and 1141 children’s guardians in these regions were surveyed and evaluated. It was used to examine the differential effects of different family parenting styles (EMBU) on preschool children’s eating behavior (CEBQ), while quality of survival (QLSCA) and nutritional literacy (NLS) played a mediating role in the process. The results showed that at the direct effect level, authoritative, authoritarian, coddling, and neglectful family parenting styles had significant effects on preschool children’s eating behavior (-0.161 ≤ β ≤ 0.232, p < 0.05); at the indirect effect level, family survival quality (QLSCA), and nutritional literacy (NLS) under the influence of different family parenting styles (EMBU) on children’s eating the total indirect effect was [OR] 0.273, 95%: CI 0.181–0.368. It is evident that it is imperative to develop good eating behaviors in children at preschool age.
Exploring factors influencing nurses’ attitudes towards their role in dental care
Authors: Gaffar Balgis , Bakhurji Eman , AlKhateeb Reem , AlHashim Hussain , AlGaoud Hadeel , AlDaamah Ziyad , AlSaleh Jamal , Aldamanhori Rand , AlHamid Shahad , AlBarrak Alanoud , Siddiqui Intisar Ahmad , Virtanen Jorma I.
Published: July 2023

Background

The burden of oral disease requires collaboration between health care professionals. Nurses are frequently exposed to patients and can play a vital role in prevention of oral diseases. This study aimed to investigate nurses’ attitudes towards their role in dental care and its associated factors.

Methods

This cross-sectional, survey-based study recruited a total of 525 nurses in Eastern Saudi Arabia, using a snow-ball sampling technique. Data was collected using an online, pre-validated 40-item questionnaire with four domains (attitudes, knowledge, practices, and demographic data).

Results

Nurses showed satisfactory attitudes (52.8 ± 8.2) and average knowledge (13.4 ±3.9). More than two thirds (70.3%) reported responding to patients’ questions about oral health conditions, 47.1% and 19.7% conducted oral health screening and education respectively. Referral practices were reported by 266 (50.7%) of the participants with pain being the main reason for referrals. Attending lectures/ trainings on oral health and having a formal education about oral health were significantly associated with nurses’ positive attitudes towards their role in dental care (P<0.001). Conducting oral health screening or education were also significantly associated with positive attitudes (P = 0.001).

Conclusion

Positive attitudes were observed among those with undergraduate oral health backgrounds, in continuous education, and those who were involved in oral health screenings. There is a need for under and postgraduate inclusion of oral health training in nurses’ education.
Development of EST-SSRs based on the transcriptome of Castanopsis carlesii and cross-species transferability in other Castanopsis species
Authors: Zhong Xiaoru , Xu Mengyang , Li Ting , Sun Rongxi
Published: July 2023

Castanopsis carlesii(Hemsl.) Hay. is a widely distributed and dominant tree species native to subtropical China with significant ecological and economic value. Due to serious human-related disturbance, its wild resources have been increasingly reduced, and whether may result in the loss of genetic diversity. However, no population genetics studies of naturalC.carlesiihave been reported to date. Microsatellite markers have been a useful tool in population genetics. Therefore, we developed EST-SSR markers based on the transcriptome sequencing ofC.carlesiileaves. A total of 149,380,224 clean reads were obtained, and 63,012 nonredundant unigenes with a mean length of 1,034 bp were assembled and annotated based on sequence similarity searches in the Nr, Nt, KO, SwissProt, PFAM, KOG, and GO databases. The results showed that only 5,559 (8.82%) unigenes were annotated in all seven databases, but 46,338 (73.53%) could be annotated in at least one database. A total of 31,459 potential EST-SSRs were identified in 18,690 unigenes, with an average frequency of one SSR approximately 2 kb. Among the 100 EST-SSR primer pairs designed, 49 primer pairs successfully produced the expected product by amplification, with a success rate of 49%, but only 20 primer pairs showed abundant polymorphisms. Polymorphisms were verified using 25 samples fromC.carlesiiin Qimen, Anhui. A total of 119 alleles were detected, with a mean number of alleles (Na) of 5.95 per locus and a mean polymorphism information content (PIC) of 0.6125. All the 20 newly developed EST-SSR markers were verified in otherCastanopsisspecies (C.sclerophylla,C.lamontii,C.fargesii,C.eyreiandC.jucunda). Sixteen primer pairs showed successful amplification in all fiveCastanopsisspecies (80%), and the transferability ratios ranged from 90% to 100%. These developed EST-SSR markers can be applied to population genetic and germplasm evaluations ofC.carlesiiand related species.
Certa via cap a l’ànima del món
Authors: Ferrer Roger
Published: July 2023

L’any 2021 un col·lectiu d’artistes va inaugurar a Girona una instal·lació que mereix una anàlisi detallada, donada la densitat de referències que presenta. El col·lectiu va titular la instal·lació Incerta via, un projecta on explícitament pretenien fer una recerca en les arrels espirituals de l’art, un plantejament que es posava de palès a les diverses parts de la instal·lació, organitzades com cinc etapes d’un procés. La intenció espiritual, segons la interpretació proposada a l’article, entronca amb els misteris de l’Antiguitat i amb l’hermetisme neoplatònic renaixentista, consistiria en estimular la imaginació per, amb aquesta, intuir una via d’ascens cap al món intel·ligible en termes platònics. Incerta via plantejava un recorregut físic per a, per analogia, traslladar-se a una geografia imaginal, una trajectòria física anàloga a la duta a terme per l’anima mundi platònica i que induís a l’experiència d’un procés de comprensió anímica. La manera de comunicar coneixement en aquesta dimensió és mitjançant imatges simbòliques enigmàtiques. Amb aquest horitzó cultural, objectius i experiències, la instal·lació actualitzaria els misteris de l’Antiguitat, replicaria idees de presocràtics, platòniques (Plató i neoplatònics com Plotí o Macrobi) i hermètiques (Corpus hermeticum) segons s’argumenta i es mostra a l’article.
Risk identification of PPP mode in stadiums and gymnasiums by ant colony algorithm
Authors: Qin Rongrong , Zhao Min
Published: July 2023

Aiming at the problem that the PPP model of stadiums and gymnasiums can not realize multi-dimensional risk analysis and the global risk identification ability is poor, an ant colony algorithm is proposed. Firstly, k clustering is used to cluster PPP mode data. Then, the ant colony algorithm is analyzed stochastically, and the risk set of PPP mode is obtained, which lays the foundation for later risk identification. Finally, through the random fusion function, the PPP mode risk set based on the path profile is constructed, and the optimal identification path is obtained, so as to improve the identification accuracy of PPP mode risk. MATLAB simulation shows that the ant colony algorithm proposed in this paper is superior to the risk clustering method in the overall risk identification accuracy and identification time of PPP mode. Therefore, the ant colony algorithm proposed in this paper can be used to identify the risk of PPP mode, to meet the needs of the construction of stadiums and gymnasiums.
Zmiany klimatu
Authors: Maslin Mark
Published: July 2023

Zmiany klimatu w przystępny sposób wyjaśniają, w jaki sposób człowiek wpływa na klimat planety. Teoria dotycząca zmian klimatu jest jedną z nielicznych naukowych idei, która każe nam myśleć o zmianie podstaw współczesnego społeczeństwa. Autor nie tylko relacjonuje debatę na ten temat, lecz także wyjaśnia, dlaczego temat budzi takie kontrowersje. Jakie są rozwiązania tego problemu? Jaka przyszłość czeka naszą planetę? Czy opisywane zjawiska przyniosą wkrótce koniec świata, jak uważało wielu ekologów w latach 80. i 90. XX w.?
Literatura francuska
Authors: Lyons John D.
Published: July 2023

Książka stanowi czytelny przegląd zagadnień związanych z literaturą francuską od jej początków do czasów współczesnych. Autor koncentruje się na tych dziełach, które reprezentują zmiany w literackiej i społecznej praktyce. Co odróżnia literaturę francuską od piśmiennictwa innych krajów? Jak ewoluowały konwencje i style literackie w poszczególnych okresach oraz w obrębie różnych gatunków? Dlaczego literaturę francuską można nazwać literaturą idei?
Reformacja
Authors: Marshall Peter
Published: July 2023

Reformacja to przystępne omówienie procesu, który stworzył nowoczesną Europę. Czym była Reformacja? Siłą postępu i wolności czy przyczyną konfliktów i podziałów? Pierwszorzędnym przykładem zdolności religii do inspirowania zmian społecznych czy może ostrzegawczą opowieścią o fanatyzmie i nietolerancji w imię wiary?
Terapia poznawczo-behawioralna
Authors: McManus Freda
Published: July 2023

Terapia poznawczo-behawioralna (CBT) jest formą terapii psychologicznej. To "Krótkie Wprowadzenie" zawiera przegląd tego, czym jest CBT, skąd się wzięła, czym się zajmuje i kiedy może być stosowana. Analizuje również, jak musi się ona nadal rozwijać, aby sprostać przyszłym wyzwaniom. Patrząc w przyszłość, Freda McManus omawia również, w jaki sposób skala problemów ze zdrowiem psychicznym i koszty tradycyjnych form terapii skłoniły ją do badań alternatywnych form CBT, które mają potencjał dotarcia do szerszej publiczności na całym świecie.
Arktyka
Authors: Dodds Klaus , Woodward Jamie
Published: July 2023

Arktyka domaga się uwagi. Ogrzewa się, topnieje i rozmraża, co stanowi śmiertelne zagrożenie dla społeczności, które ją nazywają domem. O wpływy na Arktyce rywalizują mocarstwa: USA, Chiny, Rosja. Arktyka to złożona przestrzeń. W publikacji omówione są najważniejsze problemy regionu w różnych aspektach – od geopolitycznego po środowiskowy. Autorzy badają przyczyny, czynniki napędzające i skutki zmian kulturowych, fizycznych, politycznych i gospodarczych oraz zastanawiają się nad przyszłością Arktyki. Jest to przyszłość nie tylko bieguna północnego, lecz także nas wszystkich.
Filozofia
Authors: Craig Edward , Leszczyński Marcin J.
Published: July 2023

Jak powinniśmy żyć? Co naprawdę istnieje? Skąd wiemy to, co wiemy? Autor omawia kluczowe pytania, którymi zajmuje się filozofia. Pokazuje wybrane ważne tematy dotyczące etyki, natury bytu oraz wiedzy za pomocą lektury Platona, Hume’a, Kartezjusza, Kanta, a także pisarzy buddyjskich. Tomik stanowi wprowadzenie do filozofii rozumianej nie tylko jako profesjonalne, naukowe badania, lecz także jako codzienne doświadczenie egzystencjalne każdego człowieka. Autor zaprasza czytelnika do filozofowania, zachęcając, by nie bał się stawiać pytań czy być krytycznym – filozofia pokazana w tym tomiku jest blisko codziennego doświadczenia.
Black Nurses Rock: Leaders in Caring for Our Communities
Authors: Tolbert-Robinson Kelly Verdelle
Published: July 2023

A nurse leader who is president of the Twin Cities Chapter of Black Nurses Rock, the largest minority nursing association in the country, recounts her journey to professional nursing and the leadership positions and experiences that have been the most passionate part of her career.
Best Practice Guru TK Jakarta Pada Pembelajaran Ecoliteracy
Authors: Siregar Ilias Nasaruddin , Budiarti Erna
Published: July 2023

Tujuan  dari  penelitian  ini  untuk  mendeskripsikan best  practice Guru  TK  Jakarta  pada ecoliteracy.  Metode  penelitian  kualitatif  dengan  subjek  11  guru  ada  TK  Provinsi  Jakarta.  Teknik pengumpulan  data  melalui  survey  mengunakan  googleform.  Analisa  data  mengunakan  reduksi, penyajian  data  dan kesimpulan. Hasil  penelitian  ini  adalah  Guru  TK  di  provinsi  Jakarta  telah mengetahui  makna ecoliteracy dan menyadari  pentingnya  membangun  kesadaran ecoliteracy. Pengalaman  untuk  menumbuhkan  kesadaran ecoliteracy dipraktekan  maupun  dilakukan  dalam pembelajaran di kelas.  Media yang digunakan berupa media visual, audio-visual maupun barang-barang asli. Guru juga memberikan contoh dalam membangun kesadaran ecoliteracy
Prompt closure versus gradual weaning of external ventricular drainage for hydrocephalus following aneurysmal subarachnoid haemorrhage:
a statistical analysis plan for the DRAIN randomised clinical trial
Authors: Capion Tenna , Lilja-Cyron Alexander , Juhler Marianne , Møller Kirsten , Sorteberg Angelika , Rønning Pål André , Poulsen Frantz Rom , Wismann Joakim , Schack Anders Emil , Ravlo Celina , Isaksen Jørgen , Lindschou Jane , Gluud Christian , Mathiesen Tiit , Olsen Markus Harboe
Published: July 2023

Background: Insertion of an external ventricular drain (EVD) is a first-line treatment of acute hydrocephalus caused by aneurysmal subarachnoid haemorrhage (aSAH). Once the patient is clinically stable, the EVD is either removed or replaced by a permanent internal shunt. The optimal strategy for cessation of the EVD is unknown. Prompt closure carries a risk of acute hydrocephalus or redundant shunt implantations, whereas gradual weaning may increase the risk of EVD-related infections.
Methods: DRAIN (Danish RAndomised Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage) is an international multicentre randomised clinical trial comparing prompt closure versus gradual weaning of the EVD after aSAH. The primary outcome is composite of VP-shunt implantation, all-cause mortality, or EVD-related infection. Secondary outcomes are serious adverse events excl. mortality and health-related quality of life (EQ-5D-5L). Exploratory outcomes are modified Rankin Scale, Fatigue Severity Scale, Glasgow Outcome Scale Extended, and length of stay in the neurointensive care unit and hospital. Outcome assessment will be performed 6 months after ictus. Based on the sample size calculation (event proportion 80% in the gradual weaning group, relative risk reduction 20%, alpha 5%, power 80%) 122 participants are required in each intervention group. Outcome assessment for the primary outcome, statistical analyses, and conclusion drawing will be blinded. Two independent statistical analyses and reports will be tracked using a version control system, and both will be published. Based on the final statistical report, the blinded Steering Group will formulate two abstracts.
Conclusion: We present a pre-defined statistical analysis plan for the randomised DRAIN trial, which limits bias, p-hacking, and data-driven interpretations. This statistical analysis plan is accompanied by tables with simulated data, which increases transparency and reproducibility.
Trial registration: ClinicalTrials.gov identifier: NCT03948256
Efficacy and safety of totally laparoscopic gastrectomy with Uncut Roux-en-Y for gastric cancer: A dual-center retrospective study
Authors: Chen Yizhen , Zheng Yuanyuan , Tan Song , Chen Yifan , Zheng Tao , Liu Shaolin , Mi Yulong , Lin Shentao , Yang Changshun , Jiang Jian , Li Weihua
Published: July 2023

Background Uncut Roux-en-Y (URY) effectively alleviates the common complications associated with RY, such as Roux-en-Y stasis syndrome (RSS). However, for gastric cancer (GC) patients, it is still controversial whether URY has an impact on long-term prognosis and whether it has fewer input loop recanalization. Therefore, compare whether URY and RY have differences in prognosis and long-term complications of GC patients undergoing totally laparoscopic gastrectomy (TLG). Methods We analyzed the data of patients who underwent TLG combined with digestive tract reconstruction from dual-center between 2016 and 2022. Only patients undergoing URY and RY were selected for analysis. Progression-free survival (PFS) and overall survival (OS) were estimated. Bias between the groups was reduced by propensity score matching (PSM). The Cox proportional hazard regression model was used to further analyze the influence of URY on prognosis. Results 242 GC patients were enrolled (retrospectively registered: IRB-2023-202). The URY had significantly shorter operation time, liquid food intake time, and hospital stays than the RY (P < 0.001). The URY had fewer long-term and short-term postoperative complications than the RY, especially with regard to RSS, reflux esophagitis, and reflux gastritis. The 3-year, and 5-year OS of the URY group and the RY group before PSM: 87.5% vs. 65.6% (P < 0.001), and 81.4% vs. 61.7% (P = 0.001). PSM and Cox multivariate analysis confirmed that compared to RY, URY can improve the short-term and long-term prognosis of GC patients. Conclusion TLG combined with URY for GC, especially for advanced, older, and poorly differentiated patients, can promote postoperative recovery, and improve long-term prognosis.
Global burned area increasingly explained by climate change
Authors: Burton* Chantelle , Lampe* Seppe , Kelley Douglas , Thiery Wim , Hantson Stijn , Christidis Nikolaos , Gudmundsson Lukas , Forrest Matthew , Burke Eleanor , Chang Jinfeng , Huang Huilin , Ito Akihiko , Kou-Giesbrecht Sian , Lasslop Gitta , Li Wei , Nieradzik Lars , Li Fang , Chen Yang , Randerson James , Reyer Christopher , Mengel Matthias
Published: July 2023

Fires are now raging longer and more intensely in many regions worldwide. However, non-linear interactions between fire weather, fuel, land use, management, and ignitions so far impeded formal attribution of global burned area changes. Here we show that climate change is increasingly explaining regional burned area patterns, using an ensemble of global fire models. Climate change has increased global burned area by 16% for the period 2003–2019, and raised the probability of experiencing months with above-average global burned area by 43%. Climate change-induced burned area increased in most regions, including those recently struck by extreme fire like Australia, South America and Siberia. Moreover, the contribution of climate change to burned area is rising by 0.22%year− 1 globally, with the largest increase in Central Australia (2.5%year− 1). Our results highlight the importance of immediate, drastic and sustained greenhouse gas emission reductions to stabilize fire impacts on lives, livelihoods and ecosystems.