bluuebunny/crossref_metadata_2025 huggingface dataset:
Neonatal Surgery: A Four-year Experience in a Teaching Hospital of Birgunj
Authors: Rai Binod K , Yadav Dhirendra  P , Ansari Mohammad  A , Raya Akash , Alam Mohammad  S , Sah Chandrika
Published: July 2024

Introduction: Neonatal surgery is one of the most challenging issues in medical field. The outcome of neonatal surgery is still poor in developing countries. The aim of this study was to report our experience regarding the etiological spectrum of neonatal surgical conditions and their outcome after surgical management.
Methods: A descriptive retrospective study which included all the neonatal cases that presented to Pediatric Surgery Department of National Medical College, Birgunj in the last four years. All the neonates that underwent surgery from April 2017 to March 2021 were included in the study.
Results: A total of 68 neonates were operated during the analyzed time period. Male to female ratio was 2.2:1. The age at presentation varied from 2 to 28 days and birth weight from 1.2 to 3.4 kg. Anorectal malformation (32.3%) was the commonest cause of surgery followed by tracheo-esophageal fistula (14.7%) and pyloric stenosis (8.8%). Mortality rate was 20.5% with septicemia as the commonest post operative complication.
Conclusion: The outcome of neonatal surgery in our center is not up to mark as compared with centers in developed countries. Early presentation of the patients, well equipped surgical neonatal intensive care facilities and trained manpower are needed to improve the outcome.
Etiology and Demographic Profile of Medico-legal Cases in Emergency of a University Hospital in Nepal
Authors: Khatri Pratima , Munikar Anita , Pandit Pooja , Rai Lalita , Maharjan Ramesh K , Sharma Mohan R
Published: July 2024

Introduction: Any injury or ailment where investigations by the law-enforcing agencies are crucial are considered as medico-legal cases. The objective of this study was to describe the profile of medico-legal cases presenting to the Emergency Room (ER) of Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal.
Methods: A retrospective review of medical records was done to include all medico-legal cases presented from July 2018 to June 2019.
Results: Medico-legal cases comprised 1805 (3.8%) of all cases (47,289) in the study period. The category of 25- 39 years was the commonest age group involved [659 (36.5%)] followed by 15-24 years group [582 (32.2%)]. Males were almost twice (65.8%) in number compared to females (34.2%). The top three reasons for the ER visit were road traffic accidents (RTAs) [757(41.94%)], physical assaults [356 (19.72%)] and poisoning [239 (13.24%)]. Other causes were burns, falls, sexual assaults, hanging, injuries (gunshot, electrical and machinery) and drug overdose.
Conclusion: There are significant numbers and wide varieties of medico-legal cases that present in the ER of TUTH. Young males are the most high-risk population and RTAs are the commonest etiology. This study will help the hospital in capacity strengthening of the ER, based on the volume of individual case types.
Characteristics of Articles Published in the Journal of Institute of Medicine Nepal: A Cross-sectional Study
Authors: Shrestha Lava , Singh Yogendra P , Sharma Mohan R
Published: July 2024

Introduction: Scholarly journals publish various types of manuscripts. The objective of this study was to analyze the types of articles published in the Journal of Institute of Nepal (JIOM Nepal) from 2019 April to 2021 April and describe bibliometric characteristics.
Methods: Seven issues of JIOM Nepal published from April 2019 to April 2021 were analyzed for types of study, areas of medical science, the number of authors, gender of the primary author, contributing specialty, and author’s affiliation.
Results: Total articles published were 139, with a mean number of 19.8±4.4 articles per issue. More than half of the published articles were cross-sectional studies (93, 66.9%), followed by case reports (25, 17.9%). The majority of primary authors (94, 67.6%) were faculty from constituent campuses of the Institute of Medicine (IOM) Tribhuvan University. Thirty-eight (27.3%) contributing authors were females. Fifty-three (38.1%) articles published were diagnosis- related. Authors from surgical specialties were the most common article contributors [67 (48.2 %)], while basic science specialties contributed 13 (9.4%) publications.
Conclusion: Cross-sectional studies were the most commonly published articles and surgical specialties published more than half of the articles. The majority of the articles were related to diagnosis. Greater efforts are needed to produce further progress of the journal. A mixture of original articles, reviews, and case reports from different medical domains will be more interesting to the readers.
Incidence, Risk Factors and Outcome of Neonatal Acute Kidney Injury: An Observational Study
Authors: Poudel Daman R , Basnet Srijana , Shrestha Laxman P
Published: July 2024

Introduction: Acute kidney injury (AKI) is common in neonates admitted in neonatal intensive care unit (NICU) and is associated with high death rates and prolong hospital stay. We aimed to determine the incidence, risk factors and outcome of neonatal AKI in a single tertiary center in Nepal.
Methods: This was a prospective observational study of all neonates admitted to NICU between January 2019 to December 2019. Those with AKI were further assessed for risk factors and outcomes. Neonates who survived or stayed less than 72 hours, evidence of congenital renal anomalies, or with incomplete data were excluded. Need of peritoneal dialysis, mortality and length of NICU stay were the outcomes studied among neonates with AKI. Logistic regression models were used for adjustment of covariates and risk analysis were expressed in terms of odds ratio with its 95% confidence interval.
Results: The incidence of AKI was 37.5% (42/112 patients). Compared with neonates without AKI, those with AKI had a lower birth weight (2421±960 vs 1741±1142gram, p<0.001) and a lower gestational age (36.1±7.8 vs. 32.4±3.9 weeks, p<0.001). Sepsis (OR, 4.5; 95% CI, 0.7–30) and nephrotoxic drug exposure (OR, 4; 95% CI, 1.4–7) were significantly associated with increased AKI risk. Mortality was 40% (17/42) among neonates with AKI and 3% (2/70) among those without AKI (p<0.001).
Conclusion: Over one-third of neonates in NICU developed AKI. Prematurity, low birth weight, sepsis and nephrotoxic drug exposure were risk factors for Neonatal AKI. Mortality was almost 50% in neonatal AKI
Chief Complaints of Patients Seeking Periodontal Treatment: An Institutional Study
Authors: Bista Soni , Ranjit Rebicca , Subedi Suraksha
Published: July 2024

Introduction: The patient’s chief complaint is considered a vital component during diagnosis and treatment planning, but it is usually influenced by the severity of the disease. The aim of this study was to identify the most common chief complaints among patients visiting a Tertiary Care Center.
Methods: This is a descriptive cross sectional study, carried out from September, 2020 to March, 2021 at Gandaki Medical College Teaching Hospital. Ethical approval was taken from Institutional Review Committee (Reference Number:96/77/78). Convenient sampling was done. The relevant presenting chief complaints were recorded and a rank order was created based upon their frequency. The data were entered into the excel sheet and the frequency distribution of the parameters were analyzed.
Results: Among 420 patients, the most common chief complaint was deposits/stains, which was found to be 136 (32.38%) (0.27-0.37 at 95% confidence interval). The second most common complaint was bleeding gums, which was found to be 45 (10.71%), and the third was loose teeth 43 (10.24%), followed by pain 42 (10%), and gum swelling 33 (7.86%). The least common complaints reported were oral ulcer, tooth replacement, etc.
Conclusion: The most common chief complaint was deposit/stains which was lower in our study when compared to other studies done in similar settings.
Pregnancy Outcome in Women with Decreased Fetal Movement Beyond 34 Weeks of Gestation
Authors: Koirala Poonam , Ghimire Asmita
Published: July 2024

Introduction: The fetal movement though subjective still is considered an important sign of fetal well-being. It is used as the first method for fetal well being assessment. Decreased fetal movement (DFM) always alerts the obstetricians and needs appropriate intervention as it is generally found to be associated with poor fetomaternal outcome. This study was conducted to determine the pregnancy outcome in women with decreased fetal movements at gestational age ≥34 weeks to 42 weeks of gestation.
Methods: This was a hospital- based retrospective observational study done in Obstetrics and Gynecology Department of Tribhuvan University Teaching Hospital, Kathmandu, Nepal from April 2020 to April 2021. Descriptive analysis and data processing was done by using IBM SPSS Statistics 22.
Results: There were a total of 82 women with decreased fetal movement. Among these, induction of labor was done in 35.5%, while 23.1% had preterm delivery, 47.6% had cesarean delivery and 51.1% had vaginal delivery with 1.2% vaccum delivery. Though there were higher rates of low APGAR score (15.8%), meconium stained liquor (MSL) (21.9%) and Neonatal Unit admission (NNU) (21.9%), all the babies admitted were discharged except for one perinatal death (1.2%). There was no still birth.
Conclusion: Although perinatal mortality was low in women with decreased fetal movement with negligible still birth, however there were increased MSL and neonatal admission. Hence raising awareness of DFM among women, its early identification, further assessment with ultrasound, cardiotocogram and structured management protocol is beneficial .
Demography and Outcome of Pediatric Traumatic Brain Injury; Experience from a University Teaching Hospital in Nepal
Authors: Dahal Sandesh , Shrestha Dipendra K , Pradhanang Amit  B , Sedain Gopal , Shilpakar Sushil K , Sharma Mohan R
Published: July 2024

Introduction: Traumatic brain injury (TBI) is one of the significant causes of disability and death. It is a common cause of emergency neurosurgical consultation. Due to differences in physiology and management strategy, outcomes of pediatric TBI are different. This study purposes to describe the demography, clinical-radiological characteristics, and outcome of patients with pediatric TBI.
Methods: A retrospective study of 112 children of age up to 18 years admitted to the Neurosurgical Department in Tribhuvan University Teaching Hospital following TBI from August 2021 to July 2022 was conducted. Variables analyzed were the demographics, clinical characteristics, imaging findings, management strategies, and outcome.
Results: Median age was 5.5 years. The male-to-female ratio was 2.3:1. Falls followed by road accidents (RTA) were the most common mode of injury. A significant number of patients (62, 55.3%) presented after 24 hours of injury. Vomiting (67, 59.8%) was the commonest symptom followed by loss of consciousness (60, 53.6%). Post-traumatic seizure was observed in 13 (11.6%) of the children; however, had no association with the outcome. Mild, moderate, and severe TBI were seen in 80.3%, 17.8%, and 1.7% respectively. Extra-axial hematomas (40%) were the most common findings followed by skull fractures (33.9%). Intensive care was required in 13 (11.6%) and 34 (30%) required surgery. Craniotomy (30.3%) was the most common procedure. Good outcome at discharge was seen in 107 (95.5%) of patients.
Conclusion: Falls and RTAs were the commonest causes of pediatric TBI. In our study, a significant number of the patients presented after 24 hours of injury. Craniotomy was the most common managment and most of the children had good outcomes at discharge.
Surgeon-Powered Robotics in Minimally Invasive Surgery: Case Report from Nepal
Authors: Shrestha Sujan , Gautam Sujan , Shrestha Sandip , Subedi Sushil K , KC Ajay , Pradhan Susan
Published: July 2024

Minimally-invasive surgery is the standard of care in many surgical diseases. Robotic surgery has mitigated nearly all limitations of laparoscopic surgery but with a big cost tag. Surgeon-powered robotic instruments were developed with the concept of providing similar advantages to the robotic platforms but with affordable costs. We report three cases of hernia, one hiatus hernia, and two inguinal hernias managed using surgeon-powered robotics platform. It provides additional maneuverability in minimal invasive surgical dissection and suturing. Surgeon powered robotic surgery may be a cost-effective viable alternative to robotic surgery in developing country like Nepal.
Arch Form and Mathematical Ratio in Orthodontics Patients: A Descriptive Cross-sectional Study
Authors: Maharjan Surendra , Rajbhandari Anjana , Pradhan Resina , Bajracharya Manju , Manandhar Pushkar , Pant Bashu D
Published: July 2024

Introduction: Orthodontic treatment aims to achieve a pleasing and stable occlusion. To attain these, the patient's arch shape should be determined before treatment and maintained during treatment. Many attempts have been made to find out the original arch form, but those procedures have had some difficulties. The aim of this study was to determine the arch form using a comparatively simpler mathematical ratio.
Methods: In this observational, descriptive cross-sectional study, 300 maxillary pretreatment casts from various malocclusion cases were collected. To determine the arch form, the mathematical ratio (CD/CW)/ (MD/MW) was used. Data were collected in Microsoft Excel and analyzed in IBM SPSS for descriptive statistics and one way ANOVA.
Results: Among 300 individuals, 108 (36%) were males and 192 (64%) were females. In 29 (9.67%) males had square, 48 (16%) had oval, and 31 (10.33%) had tapered shaped arch forms, while 54 (18%) females had square, 77 (25.67%) had oval, and 61 (20.33%) had tapered shaped arch forms. The mean values of arch form were significant in both gender and age groups.
Conclusion: The majority of participants had an oval arch form, followed by a tapered and square-shaped arch form.
Influence of Customer Relations Capabilities on Competitive Advantage of Level 5 Public Hospitals in Kenya
Authors: Kaguu Lydia Muthoni Kaguu , Mutisya Mary
Published: July 2024

The healthcare industry in Kenya is going through many challenges including reduced funding, shortage of staff, technological innovations and changing customer expectations which puts pressure on public hospitals to attain competitive advantage. The purpose of the study was to examine the influence of customer relations capabilities on competitive advantage of Level 5 public hospitals in Kenya. This study was anchored on dynamic capabilities theory. Positivism philosophy applied, where a descriptive correlational research design and a structured questionnaire were applied to gather quantitative data. The study focused on 33 Level 5 public hospitals in Kenya and the study population comprised of 495 CEOs, departmental heads and administrative heads of all the Level 5 public hospitals. Stratified random sampling was used to pick a sample of 222 respondents. The study’s data analyses involved descriptive statistics (frequencies, means and standard deviations) and inferential analysis (simple linear regression analysis). The findings revealed that customer relations capabilities had a statistically significant and positive effect on the competitive advantage of Level 5 public hospitals in Kenya (β = 0.629, p < 0.05). The study concluded that customer relations capabilities are instrumental towards attainment of competitive advantage of the Level 5 public hospitals in Kenya. Based on the conclusion of the study, it is recommended to the top management of level 5 public hospitals to adopt systems and processes in their hospitals that gathers information to investigate customer needs.
Effect of Technological Capabilities on Transient Competitive Advantage among Hospitals in Kenya
Authors: Amboyi Evalyne Khamasi , Kaluyu Veronica , Okello Gabrielle
Published: July 2024

This research aimed to address a significant gap by empirically examining the link between technological capabilities and transient competitive advantage, a topic largely overlooked in the Kenyan healthcare sector. The study combined descriptive and correlational research designs. The target population comprised 476 top managers of private hospitals, with a calculated sample size of 247. Probability sampling techniques, including stratified random sampling were used in determining the sample participation per hospital. Data collection was then done using questionnaire guide. Confirmatory Factor Analysis (CFA) and Structural Equation Modelling (SEM) were used to analyse the relationship between technological capabilities and transient competitive advantages. Results indicate a 84.6% response rate, revealing variations in private hospitals’ transient competitive advantage and technological capabilities. The validity and reliability tests demonstrate a satisfactory assessment of the data collection instruments. The SEM analysis reveals a significant positive impact of technological capabilities on transient competitive advantage (path coefficient = 0.943). The study concludes that technological capabilities are pivotal in shaping transient competitive advantage in Kenyan private hospitals, emphasizing the need for strategic investments in technology, partnerships, innovation, and a market-oriented approach. The study recommends healthcare practitioners to invest in strategic technology investments, partnerships, foster innovation, and a market-oriented approach for continuous adaptation.
INTENSIFICATION OF SUPERCRITICAL EXTRACTION OF TRITERPENE SAPONINS FROM ARALIA MANDSHURICA AND PANAX GINSENG
Authors: Khudeev Illarion I. , Lebedeva Elena S. , Artemiev Artem I. , Kazeev Ilya V. , Menshutina Natalya V.
Published: July 2024

This work is devoted to experimental research of the extraction of triterpene saponins from Aralia mandshurica and Panax ginseng using the supercritical extraction process. Triterpene saponins of Aralia mandshurica and Panax ginseng are polar compounds. Therefore, the supercritical extraction process was carried out in a supercritical carbon dioxide using a co-solvent – an aqueous solution of ethanol. A technique for carrying out the supercritical extraction process is described and a schematic diagram of a supercritical extraction apparatus proprietary design with an extractor volume of 22 ml is presented. The kinetic curves of the yield of extract are presented. This work is considering methods of intensification of the supercritical extraction process: optimization of operational conditions, superposition of fields. Optimization of operational conditions was carried out in the temperature range of 40 to 50 °С and pressures range of 120 to 200 bar. The phenomenon of retrogradation was noted when the temperature of the supercritical extraction process from Panax ginseng changed. The influence of the method of supplying supercritical carbon dioxide (constant supply throughout the process and pulse supply) was studied. The pulsed supply made it possible to significantly reduce the consumption of carbon dioxide – by 59.5% relative to the experiment with a constant consumption of carbon dioxide. The study of the effect of ultrasonic exposure (the method of superimposing fields) on the intensity of the supercritical extraction process was carried out. The usage of ultrasound led to an increase in the yield of extract. The largest amount of extract from Aralia mandshurica and Panax ginseng was obtained at 50 °С and 200 bar with the usage of ultrasonic exposure and at a constant supply of carbon dioxide (500 g/h) throughout the process.
For citation:
Khudeev I.I., Lebedeva E.S., Artemiev A.I., Kazeev I.V., Menshutina N.V. Intensification of supercritical extraction of triterpene saponins from Aralia mandshurica and Panax ginseng. ChemChemTech [Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol.]. 2023. V. 66. N 3. P. 108-118. DOI: 10.6060/ivkkt.20236603.6737.
Application of PID and self-tuning fuzzy PID control methods in the control of non-linear magnetic levitation system
Authors: Karabacak Yusuf
Published: July 2024

Because of the Magnetic Levitation System's (MLS) low energy consumption and little friction two factors that are deemed crucial for unstable and nonlinear systems MLS research is now being conducted in the engineering area. This article discusses the comparison of the performance of control theories used by applying advanced control theories to cope with the complexity of the structure and controllability difficulties of MLS. The control methods compared are Proportional–Integral–Derivative (PID) and Self-Tuning Fuzzy PID (STFPID) methods. These methods were developed in the MATLAB environment. The MLS model created in the MATLAB environment was subjected to the suggested control methods, and the outcomes were compared. The outcomes unequivocally demonstrate that MLS location control may make use of PID and STFPID techniques. Four criteria were used to compare the developed control approaches performances. These are the criteria; rise time, settling time, percent maximum overshoot and overshoot value. It is clearly seen in the results that the STFPID control method provides control of the MLS with greater stability than the PID control method.
FATORES RELACIONADOS AO USO DE METILFENIDATO POR ESTUDANTES DE MEDICINA SEM DIAGNÓSTICO DE TRANSTORNO DE DÉFICIT DE ATENÇÃO E HIPERATIVIDADE: revisão integrativa
Authors: Pereira Bonicontro Bárbara , Toneli Primo Gabriela , Merenciano Xavier Nicolly , Silveira Sartori Patricia , Anne Péret Guimarães Ursulla , Pereira Santos William , Aparecida Fófano Gisele
Published: July 2024

Introdução: Drogas psicotrópicas prolongam o estado de atenção, melhoram o humor e a ação nootrópica. Universitários hígidos as utilizam com a finalidade de ampliar a concentração e o rendimento em suas atividades, devido ao ambiente de alto nível de exigência, dedicação e produtividade acadêmica, mesmo acarretando riscos à saúde. Objetivos: I) identificar as evidências sobre o uso abusivo de Metilfenidato entre estudantes de Medicina sem diagnóstico de TDAH aos seus prováveis motivos; e II) abordar os efeitos adversos causados pelo uso indiscriminado do Metilfenidato e relatar os possíveis efeitos adversos causados pelo uso indiscriminado dessa substância. Métodos: Trata-se de uma revisão integrativa, com busca bibliográfica nas bases de dados on-line PUBMED, SCIELO e NCBI. Foram incluídos artigos originais, na íntegra, em português ou inglês, publicados de 2010 a 2020. Foram excluídos: estudos realizados com plantas e animais, estudos laboratoriais com análise de substâncias biológicas, artigos não originais ou duplicados. Resultados: As principais motivações do consumo de psicotrópicos em acadêmicos de Medicina geralmente são para permanecer alerta, compensar a privação do sono e melhorar raciocínio, atenção e memória, sendo que o consumo aumenta nos períodos de prova e nos extremos do curso. Considerações Finais: Diante do cenário exaustivo vivenciado pelos estudantes de Medicina, a demanda pelos psicotrópicos aumenta devido à sobrecarga de estudos e ao cansaço diário. Comumente, há queixa de desatenção durante as aulas e avaliações, logo, os acadêmicos recorrem aos nootrópicos a fim de potencializar o rendimento acadêmico e o desempenho cognitivo, ainda que haja evidências de risco para saúde em razão do uso abusivo destas substâncias.
Students' Communication Behavior in Achieving Learning Targets in Kampung Inggris Pare Kediri, East Java
Authors: Putri Rika Ilma , . Mursalim , . Arianto
Published: July 2024

The students who are immigrants from various regions in Inonesia come to Kampung Inggris to learn English English is a foreign language which requires practice in order to become accustomed to English. In achieving the learning goals, students communicate, either using language that is done verbally or using movements or visualizations in a non verbal way. Therefore, it is interesting to examine the communication behavior of student, both verbal and non-verbal in Kampung Inggris Pare Kediri in achieving learning targets. The research method uses qualitative phenomenology by thoroughly describing the data obtained during the research process. The data collection technique uses observation, in-depth interviews, and documentation. The theoretical foundation uses the theory of operant conditioning which is a conditioning process of strengthening behavior that can result in the behavior recurring or disappearing according to wishes. Moreover, it also uses the theory of social construction where there is social knowledge and reality. The results showed that Students' daily verbal communication behavior is not always in English. Only in the dormitory students must use English. Students choose a conversation partner that is one level or a higher level. Students switch reading to English reading. Non-verbal communication behavior when students wear casual clothes. Facial expressions and body movements can help in interpreting conversations. Confused students can be identified by a weakened intonation of their voice and a tendency to be silent. The more confident the student, the higher the intonation.
Boosting Financial Audits with AI: Insights from Auditors at Public Accounting Firms Affiliated with OAI Solusi Manajemen Nusantara
Authors: Payamta Payamta
Published: July 2024

The integration of artificial intelligence (AI) into auditing practices promises to revolutionize the profession by enhancing efficiency, accuracy, and insight. This study investigates AI's impact on 150 auditors from OAI Solusi Manajemen Nusantara member firms across Indonesia, utilizing a Google Form survey. AI automates tasks such as data collection, reconciliation, anomaly detection, and risk assessment, allowing auditors to focus on high-value activities like fraud detection and generating actionable insights. Continuous auditing enabled by AI ensures timely issue detection and resolution, improving transparency and stakeholder communication through more informative audit reports. Challenges include ensuring data quality and understanding AI model outputs, critical for auditors to effectively interpret and trust AI-driven recommendations.
PEMBERDAYAAN KELOMPOK KREATIVITAS IBU-IBU PKK KELURAHAN PETERONGAN SEMARANG SELATAN MELALUI PEMBENTUKAN KELOMPOK USAHA BERSAMA
Authors: Malebra Irawan , Umar Farouk  , Nur Rini  , Sugiyanta Sugiyanta  , Sandi Supaya  , Paniya Paniya  , Sri Wahyuni  , Sri Eka Sadriatwati  , Makmun Riyanto
Published: July 2024

The partners in this community service programme are PKK women of Peterongan Village, South Semarang. The objectives of this community service programme are to form a joint business group, improve business management skills, improve skills in making snacks, and increase family income. Partners in this activity are a group of PKK Peterongan mothers who have free time at home with busy taking care of children and family. Household income is not sufficient to meet the needs, so additional income is needed. The problems in the partners are that a joint business group has not been formed, the entrepreneurial spirit still needs to be developed, the skills of managing a business, making snacks, family income still needs to be increased. From these problems, the solution agreed upon by the partners is the formation of a joint business group, development of entrepreneurial spirit, training and practice in making business plans, making snack products. The output target in this programme is the formation of a joint business group, the entrepreneurial spirit increases 100%, the skills in making business plans increase 100%, the skills in making snack products increase 100%, the family income increases 10% per capita in each family.
Hemodiyaliz Hastalarının Yaşam Kalitesi ve Beslenme Durumlarının Değerlendirilmesi
Authors: Şahin Dilek Ayfer , Erol Özgül
Published: July 2024

Amaç: Bu araştırma, hemodiyaliz hastalarının yaşam kalitesi ve beslenme durumunu değerlendirmek amacıyla yapıldı.
Yöntem: Kesitsel olarak gerçekleştirilen bu tanımlayıcı araştırmaya, 115 hemodiyaliz hastası dahil edildi. Veriler hasta bilgi formu, SF-36 Yaşam Kalitesi Ölçeği ve Subjektif Global Değerlendirme Formu ile toplandı. Verilerin analizinde Ki-kare testi, student t testi, Mann-Whitney U testi, Tek yönlü varyans analizi ve Kruskal Wallis testi kullanıldı. p
DNA Genetics and UHPLC-Q-TOF-MS Analysis of Phytochemicals for Asparagus racemosus Roots
Authors: Nguyen Thi Huong , Do Ngoc Thuy , Phung Van Trung , Le Ngoc Hung , Mai van Nam
Published: July 2024

The medicinal herb Asparagus racemosus has been used in traditional medicine to treat various diseases such as cough, diarrhoea, diabetes, gastric issues, gonorrhoea, headaches, piles, rheumatism, and even lactation enhancement. This study explores the genetic information and phytochemicals of the species native to Gia Lai province, Vietnam before its conservation and cultivation. Five species of A. racemosus were analyzed using the trnL-e/trnL-f regions sequence. A. racemosus roots were extracted by water then Ultra-High-Performance Liquid Chromatography coupled with Quadrupole/Time-Of-Flight Mass Spectrometry (UHPLC-Q-TOF-MS) spectroscopy was used to screen for their phytochemicals. We have confirmed the DNA genetics of A. racemosus species collected in Gia Lai, Vietnam. In water extract of A. racemosus roots, UHPLC-Q-TOF-MS tentatively identified two flavonoids (Quercetin-3-glucuronide, Rutin), five steroidal saponins (Shatavarin I, Shatavarin IV, Shatavarin IX, Asparacoside, Asparanin A), and two steroids (β-sitosterol, Daucosterol). The experimental findings confirm the A. racemosus species for conservation and cultivation in Vietnam and contribute the benefits to the chemical literature of Vietnamese natural flora. A. racemosus should be further studied for pharmaceutical activities.
Auxological Status of Modern Primary School Students of Nizhny Novgorod Region
Authors: Kalyuzhny Evgeniy Aleksandrovich , Mukhina Irina Vasilievna , Bogomolova Elena Sergeevna , Galova Elena Anatolyevna , Puzhak Svetlana Andreevna , Baklanova Ekaterina Sergeevna
Published: July 2024

The article describes the characteristics of the resulting effector auxological morpho-functional status of primary school students, differentiated by gender and administrative-territorial characteristics. The objectives of the study included studying the auxological status of children adolescents, and primary school students in the Nizhny Novgorod region in the context of the peculiarities of the exoenvironment of residence in urban and rural areas. Materials and methods: Own data served as a source of anthropometry and physiometry indicators of the objective population of the region. The analysis of anthropological indicators was carried out by discretizing data sets that state an objective picture of auxological indicators at the regional level, taking into account the peculiarities of anthropogenic loads characteristic of the place of residence of the observed population groups. To quantify the values ​​and statistical differences in indicators by age, gender, and administrative characteristics, the median, standard deviation, and criteria were used: Fisher, Wilks, and Mahalanobis, with an error of differences at p < 0.05. Results: The stability of the age-sex evolution of auxological indicators is shown; the age-sex and territorial dimorphism of total body sizes is shown at 7-10 years of age, with residents of rural areas lagging in the observed indicators. Hemodynamic indicators in both boys and girls significantly prevail among students living in the metropolis relative to their rural counterparts, except diastolic blood pressure. Variance analytics shows differences in the distributions of anthropometry and hemodynamics, both by age and by the urbanization factor at p < 0.001. In the observed age period, at the initial stage, hemodynamic indicators act primarily as modifiers of the metropolis and rural groups. From the age of ten, according to the standardized coefficients of discriminant functions, according to the first canonical variable, the division of series also occurs according to anthropometric characteristics, among which the greatest contribution to the division of groups is made by body weight and body length, and the hemodynamic characteristic - diastolic blood pressure - has also proven to be decisive. Conclusion: Primary school students living in rural areas and in the metropolis of the Nizhny Novgorod region determine the observed indicators ambiguously; if residents of the metropolis state greater results for all observed auxological indicators, then rural peers demonstrate, while lagging in all observed indicators, greater indicators of diastolic blood pressure, which suggests a strain on adaptation mechanisms central character.
Machine Learning Applied to Electric Vehicle Routing Problem: Optimizing Costs for a Sustainable Environment
Authors: Jalel Euchi
Published: July 2024

The global move towards Electric Vehicles (EVs) marks a crucial step towards sustainable transportation. However, effectively integrating EVs into the current infrastructure demands more than technological advancements. One of the key challenges is optimizing the routing of EVs to minimize costs and environmental impact. This editorial examines the role of Machine Learning (ML) in addressing the electric vehicle routing problem (ESVRP), highlighting its potential to transform cost optimization and sustainability in transportation. Routing is a fundamental part of transportation logistics, influencing efficiency, cost, and environmental impact. While traditional internal combustion engine vehicles have established routing systems, EVs present unique challenges such as limited battery capacity, longer refueling times, and fewer charging stations. These factors require advanced routing solutions that can dynamically adapt to various constraints.
Władysław Natanson (1864-1937).Odsłonięcie tablicy pamiątkowej na UJ
Authors: Spałek Józef ,   Instytut Fizyki Teoretycznej UJ, Goc-Jagło Danuta ,   Instytut Fizyki Teoretycznej UJ
Published: July 2024

On January 18, 2024, a commemorative plaque dedicated to Prof. was unveiled. Władysław Natanson, co-organizer and first president of the Polish Physical Society (1920-1922). The ceremony was attended by, among others: prof. Piotr Kuśtrowski, vice-rector of the Jagiellonian University, prof. Teresa Rząca-Urban, president of the PTF, prof. Bogdan Kowalski, secretary of the PTF Board, prof. Ewa Brocławik, director of the 3rd Faculty of the Polish Academy of Sciences, prof. Ewa Gudowska-Nowak, dean of the Faculty of Physics, Astronomy and Applied Computer Science of the Jagiellonian University, prof. Wojciech Macyk, dean of the Faculty of Chemistry of the Jagiellonian University, members of the Management Board of the Krakow Branch of the PTF, as well as descendants of prof. Natanson and numerous guests. After unveiling the plaque, a memorial lecture was delivered by prof. Józef Spałek.
The Relationship of Women's Knowledge and Attitudes with Pap Smear Examination at Bhayangkara Hospital Makassar
Authors: Ekayanti Ekayanti
Published: July 2024

According to WHO (2011), cervical cancer is one of the leading health problems for women throughout the world with an estimated 529,409 new cases and around eighty-six percent (86%) in developing countries. In Indonesia, it is estimated that every day 40-45 new cases appear, 20-25 people die, meaning that every 1 hour it is estimated that 1 woman dies due to cervical cancer. The aim of the research was to determine the relationship between women's knowledge and attitudes with pap smear examinations at Bhayangkara Hospital Makassar. This research uses analytical research methods. The population is women who come for check-ups at Bhayangkara Hospital Makassar Family Planning Polyclinic. The sample studied was 39 people using accidental sampling technique. The research started from March 7 to April 7 2016. Data was collected using a questionnaire and then statistical analysis was carried out using the chi square test with the alternative Fisher's exact test with a significance level of ? < 0.05. The research results showed that the majority of respondents had insufficient knowledge, namely 29 people (74.4%). Based on attitudes, the majority of respondents with a negative attitude were 32 people (82.1%), and the majority did not have a pap smear, namely 27 people (69.2%). The results of the Fisher's exact test obtained a value of p = 0.004 < 0.05, and p = 0.002 < 0.05. Based on the research results, it was concluded that there was a relationship between women's knowledge and pap smear examinations, and there was a relationship between women's attitudes and pap smear examinations. It is recommended that health workers, considering the low level of public behavior regarding the importance of Pap smears, need to take several steps to increase people's knowledge, attitudes and behavior regarding the importance of Pap smears.
Overview of Knowledge and Attitude of Adolescents Towards Free Sex in the Pannampu District, Makassar City
Authors: Nurhayati Nurhayati
Published: July 2024

Problems that are often experienced by teenagers today are issues surrounding sexuality, especially premarital sex or free sex. Data from the World Health Organization (WHO), which conducted research in several developing countries, shows that around 40% of young men and young women aged 18 years have had sex even without being married. Based on research in various big cities in Indonesia, around 20 to 30% of teenagers admit to having had sex. The aim of the research was to determine the description of teenagers' knowledge and attitudes towards free sex in Pannampu Village, Makassar City. The type of research is descriptive observational. The sample in the research was 98 teenagers aged 13-18 years in Pannampu Village, Makassar City, using proportional random sampling techniques. The results showed that based on knowledge, the majority of respondents had less knowledge about free sex, namely 58 people (59.2%), while based on attitude, the majority of respondents had a positive attitude towards free sex behavior, namely 66 people (67.3% ). Based on the results of the research, it was concluded that knowledge can influence teenagers' attitudes towards engaging in free sex. The better teenagers' knowledge about free sex, the better their attitudes and behavior will be in avoiding free sexual behavior. It is recommended that health workers provide education about the dangers of free sex to teenagers to increase teenagers' knowledge about the impacts that can be caused by free sex.
Examining the Benefits of Water Births in a Hospital Setting: Perspectives from Midwives and Nurses
Authors: Ghalib Qadous Shurouq , Firdaus Mohd Khairul Zul Hasymi
Published: July 2024

Objective: This study aimed to investigate the impact of midwifery-led care on maternal outcomes, maternal satisfaction, and newborn health in a hospital setting. Specifically, the study sought to compare the effects of midwifery-led care to standard care models, assess maternal preparedness for childbirth, explore rates of medical interventions, evaluate maternal satisfaction, and examine newborn health outcomes. Methods: A total of 200 expectant mothers receiving prenatal care at a tertiary hospital were recruited and randomly assigned to two groups: Group A (midwifery-led care) and Group B (standard care). Participants' demographic information, medical history, and preferences related to prenatal care were collected using a structured questionnaire. Validated surveys, including the Edinburgh Postnatal Depression Scale (EPDS), were used to assess postpartum depression. Medical records and prenatal visits were reviewed throughout the pregnancy, and postpartum follow-ups were scheduled to assess maternal outcomes. Statistical analyses were performed to compare outcomes between the two groups. Results: Participants in the midwifery-led care group reported significantly higher levels of birth preparedness (p < 0.001), and rates of medical interventions during childbirth, including cesarean sections, were significantly lower compared to the standard care group (p < 0.05). Maternal satisfaction scores were significantly higher in the midwifery-led care group (p < 0.001). Additionally, the midwifery-led care group showed lower rates of postpartum depression (p < 0.01) and higher rates of exclusive breastfeeding at six weeks postpartum (p < 0.05). Neonates born to mothers in the midwifery-led care group had significantly lower rates of neonatal complications (p < 0.01). Conclusion: The findings of this study provide strong evidence for the positive impact of midwifery-led care on maternal outcomes, maternal satisfaction, and newborn health. The personalized and woman-centered approach of midwifery-led care contributes to improved maternal preparedness, reduced medical interventions, increased maternal satisfaction, lower rates of postpartum depression, and better newborn health outcomes. These results highlight the potential benefits of integrating midwifery-led care models into maternity services, aiming to enhance the overall birthing experience and improve maternal and infant health outcomes.
La ciberseguridad y métodos de validación de los sistemas informáticos en línea: un mapeo sistemático de la literatura
Authors: Rios Alfredo Horacio
Published: July 2024

Context: Web applications are subject to attacks from different locations at various levels of scale and complexity. In this context, both developers and researchers have proposed many techniques, tools and test frameworks to effectively and efficiently test the security of web applications avoiding the rise of cybercrime.Objective: Our goal is to summarize the state of the art in web application security testing that could benefit professionals to potentially use that information.Method: We reviewed and structured the body of knowledge related to web application security testing in the form of a systematic literature mapping. In this study, we posed three sets of research questions, defined selection, and exclusion criteria, and systematically developed a classification scheme. The initial group consisted of 1058 articles then after the inclusion/exclusion of articles there were 226 technical articles and applying a last filter there were 13 articles in our final group, this review includes all works until 2023.Results: This review document provides an overview of security testing of web applications with different types of authentications with a preponderance of biometric validations.
Redesigning Resettlement Homes for Internally Displaced Persons (IDPs) in Borno State
Authors: Modu Baba Shehu Alhaji , Hussaini Ibrahim Udale , Wakawa Usman Bukar , Bashir Usman Muhammed , Abubakar Sarkile Kawuwa
Published: July 2024

This study proposes a culturally informed redesign of resettlement homes for Internally Displaced Persons (IDPs) in Borno State, Nigeria. The existing housing designs often overlook the cultural values and nuances of the Kanuri people, the predominant ethnic group in the region. The research utilizes a mixed-methods approach, incorporating qualitative insights from interviews and focus groups with Kanuri community members, and data from surveys assessing current housing satisfaction, combining traditional Kanuri architectural features, spatial layouts, and social practices to create culturally responsive resettlement homes. This design intervention aims to enhance the emotional well-being, social cohesion, and resilience of IDPs in their new settlements. The study explores the impact of culturally sensitive design on the emotional well-being, social cohesion, and resilience of IDPs in their new settlements. Results indicate that incorporating traditional Kanuri design principles can significantly enhance the liveability and acceptance of resettlement homes, fostering a supportive environment that respects and preserves cultural identity. The findings underscore the importance of cultural considerations in architectural design for displaced populations, advocating for policies and practices that prioritize cultural relevance in housing solutions. This paper contributes to the broader discourse on humanitarian architecture and the role of culturally responsive design in improving the quality of life for displaced communities.
Innovation and Exploration of School-enterprise Curriculum Co-construction Mode for Business English Majors in the Era of Big Data
Authors: Ai Lijun
Published: July 2024

With the rapid development of information technology and the advent of the era of big data, the changing demand for business English talents has put forward new requirements for the development of business English teaching. Based on the theoretical foundation of the school-enterprise curriculum co-construction mode of the business English major, this paper sorts out the innovative ideas of the school-enterprise curriculum co-construction of the business English major. On this basis, it proposes implementation paths for the school-enterprise course co-construction mode, such as strengthening the cooperation and coordination between schools and enterprises, improving teachers' innovative ability and students' practical application ability, and optimizing the evaluation of course effects. This paper provides some ideas for cultivating business English talents to meet the needs of society and promoting the reform and innovation of business English teaching.
Decoding Health: The Power of Nutrigenomics
Authors: Krishna Pasupuleti Murali
Published: July 2024

Abstract: Nutrigenomics is an emerging field that examines the interaction between nutrition and genetics, with the goal of understanding how dietary components affect gene expression and, consequently, human health. This research article explores the theoretical foundations, practical applications, and future potential of nutrigenomics. Through comprehensive analysis, the study identifies key factors influencing nutrigenomic responses, highlights significant research findings, and discusses the implications for personalized nutrition and public health. The findings underscore the importance of genetic variability in dietary responses and the potential of nutrigenomics to revolutionize nutritional science. Practical recommendations for researchers, healthcare providers, and policymakers are provided, along with suggestions for future research to further advance the field. Keywords: Nutrigenomics, Nutrition, Genetics, Gene Expression, Human Health, Dietary Components, Personalized Nutrition, Public Health, Genetic Variability, Nutritional Science, Nutrigenomic Responses, Healthcare Providers and Policymakers.