Statistical analysis of the SARS-CoV-2 effect on the gestation and
childbirth course
Authors: Boychuk Alla V. , Berehulyak Sophia O. , Berehulyak O.O. , Yakumchuk Yulia B. 
Published: March 2024

Summary. Pregnancy is known to increase the risk of obstetric and
neonatal sequelae in many viral complications. COVID-19, according to the
WHO, is a disease caused by SARS-CoV-2 infection. Coronavirus disease in
2019, caused by severe acute respiratory syndrome, has spread rapidly around
the world and has become a pandemic. Today, data on the impact of this
disease on pregnancy and the development of possible complications for the
fetus are being actively studied. The aim of the study – to learn the effect
of SARS-CoV-2 in pregnant women on the subsequent gestation and childbirth
course; to conduct a comparative analysis of the incidence of these
complications with the overall average for the Perinatal Center "MUNICIPAL
NON-PROFIT ENTERPRISE "TERNOPIL MUNICIPAL CITY HOSPITAL No. 2". Materials
and Methods. The archived medical records including pregnancy and childbirth
record form No. 096/o were analyzed in 33 parturient women, who labored in
the Perinatal Center "MUNICIPAL NON-PROFIT ENTERPRISE "TERNOPIL MUNICIPAL
CITY HOSPITAL No.2" in 2021–2022 and had SARS-CoV-2 coronavirus during this
pregnancy. The incidence of pregnancy and childbirth complications in this
group was analyzed in comparison with the overall average for this maternity
hospital in 2021. The overall average for the Perinatal Center "MUNICIPAL
NON-PROFIT ENTERPRISE "TERNOPIL MUNICIPAL CITY HOSPITAL No.2" for 2021 was
calculated for 2218 childbirths that took place during this period. Results.
The results showed that there was an increase in the incidence of pregnancy
and childbirth complications in parturient women who had SARS-CoV-2
coronavirus during pregnancy compared with the average group. Thus, in the
study group of women after coronavirus disease, the incidence of pregnancy
complications was (compared to the average): placental dysfunction – 75.7 %
(33.6 %), gestational toxicosis development – 51.5 % (24.3 %), abnormal
amniotic fluid volume – 27.2 % (18.5 %), urinary tract infections – 15.1 %
(8.8 %). The incidence of childbirth complications in the group of women who
had SARS-CoV-2 coronavirus also increased significantly. Thus, in this group
of women the number of physiological childbirths was 45 % (with an average
of 51 %), the number of cesarean sections was 36.3 % (with an average of
25.2 %), dystocia and abnormal labors occurred in 18 % of women (with an
average of 4.4 %), vacuum extraction was used in 6 % of women (with 2.2 % in
the average group). The number of premature babies (15 %) and low
birth-weight babies (21.2 %) increased among newborns in the group of women
who had SARS-CoV-2 coronavirus. Conclusions. As a result of the analysis it
was found that parturient women after SARS-CoV-2 had a significantly higher
incidence of pregnancy and childbirth complications compared with the
average. Timely prevention and diagnosis of complications after SARS-CoV-2
allows to treat effectively and perform on time delivery in this group of
women and has positive consequences for both women and newborns