bluuebunny/crossref_metadata_2025 huggingface dataset:
Cross-sectional Prevalence Data for Lichen Sclerosis et Atrophicus in the All of Us Database: Implications for Routine Genital Skin Examination
Authors: K. Verma Kritin , Khare Ashna , Fitzgibbon Mary , Matthew Ethan , P. Friedmann Daniel , B. Tarbox Michelle , Rosen Theodore
Published: November 2024

This study aimed to investigate the prevalence of Lichen Sclerosus et Atrophicus among women aged 65 and older, utilizing data from the All of Us Database, a comprehensive initiative by the United States National Institutes of Health. The AUD, which includes de-identified patient data, was queried for female patients diagnosed with LS&A, identified by the ICD-10-CM code L90.0. Our analysis encompassed 248,130 female patients, out of which 1,087 were diagnosed with LS&A, resulting in a prevalence rate of 0.438% (95% CI: 0.412-0.464). The study revealed that the prevalence of LS&A increases with age, peaking in the 81-85 year age group, with a prevalence of 1.298% (95% CI: 1.030-1.565), although not significantly different from adjacent age groups. Racial analysis showed the highest prevalence among White patients, with a prevalence of 0.622% (95% CI: 0.581-0.663). Despite the low overall prevalence, the study suggests potential underestimation due to reliance on ICD-10 billing codes and demographic discrepancies between the AUD population and the general US population. The findings underscore the need for improved screening guidelines for genital dermatologic conditions in elderly women and enhanced training for healthcare professionals in dermatology and obstetrics and gynecology. This study highlights the importance of comprehensive databases in understanding the epidemiology of less common diseases and the need for further research to accurately estimate the prevalence of LS&A in the general population.
Stability Calculation of Irregular Structures with Irregular Disorder During Seismic Impact
Authors: Jangidze Zaza
Published: November 2024

From the point of view of modern construction, the damage to reinforced concrete large-panel and frame buildings is especially interesting. The construction of this building is very diverse. Their use has a short history. Therefore, the systematisation of damages and generalisation of results for such buildings is more difficult. Below are some statements sufficiently substantiated with factual material. It is similar to the skeleton of large-panel buildings. However, the resistance of reinforced concrete wall panels is, of course, much higher than the resistance of stone piles. That is why the panels themselves are rarely damaged by earthquakes. Relatively weak points of large-panel buildings are the edges of the panels, the support nodes on the roof panels and other connections. It is in these places that cracks, broken corners and other injuries develop during earthquakes. Three methods of restoration-reconstruction of damaged large-block multi-story buildings are proposed: metal diagonal web member and system-variable rigid in the interior space of the building, using today's terminology with seismic insulators, with the arrangement of additional frames; with reinforced-concrete pylons built over the entire height and perimeter of the building and by arranging loggias in their space; By building pylons along the longitudinal facades of the building and building a floor/floors on top of the building, along with arranging additional frames with seismic insulators if necessary.
Dual role of natural molecules in bridging cancer and Alzheimer’s disease: insights from in silico simulations
Authors: Kantarci-Carsibasi Nigar , Girgin Munteha
Published: November 2024

Cancer and Alzheimer's disease (AD) present significant socioeconomic challenges and remain without definitive cures. Existing chemotherapeutic and anti-Alzheimer drugs approved by the FDA offer limited efficacy and carry notable side effects, underscoring the need for safer, more effective therapies. Our research group has recently focused on identifying natural molecules to treat AD by targeting acetylcholinesterase. Building on this, the current study expands our approach through virtual screening of DrugBank and Zinc databases to discover natural compounds that inhibit Estrogen Receptor Alpha (ERα) for breast cancer treatment. Molecular docking and drugability analyzes identified four promising compounds: Queuine, Thiamine, Galantamine, and Folic Acid. The docking scores for Galantamine, Thiamine, Queuine, and Folic Acid were -8.8, -8.3, -8.0, and -7.5 kcal/mol, respectively. These molecules demonstrate interactions with key residues in the ERα binding site such as Glu 353 and Phe 404 through hydrogen bonding and pi-pi stacking. Similar interactions are also maintained in the FDA-approved selective Estrogen Receptor Modulators, Raloxifene and Tamoxifen. ADMET analysis indicated that these natural molecules possess favorable drug-like properties and offer a safety advantage, as they are less likely to induce deep vein thrombosis or pulmonary embolism, which are the serious side effects commonly associated with Raloxifene and Tamoxifen. A thorough literature review further highlights these compounds' neuroprotective effects, suggesting they could serve as dual-purpose therapeutics to address both cancer and AD, paving the way for integrated treatment strategies.
Hyper-Personalization with AI and Edge Computing: The Future of Customer Experience in E-commerce and Retail
Authors: - RASHEDUL ISLAM , - MD SHEAM ARAFAT , - MD Anwarul Matin Jony , - S M Shahariar Rafi , - Muhammad Saqib Jalil , - Foysal Hosse
Published: November 2024

Advancements in Artificial Intelligence (AI) and edge computing are reshaping what is possible in the world of hyper-personalization, currently powering customer experience in e-commerce and retail. In this study we explore when AI algorithms and edge computing frameworks enable real time, individualized customer interactions resulting in deeper engagement and higher loyalty. This study uses a quantitative research design to explore data driven personalization techniques with datasets from leading retail and ecommerce platforms. To evaluate the scalability and responsiveness of hyper-personalization technologies, a combination of machine learning models and terms edge computing infrastructures is methodologically analyzed. Through case studies of top tier e-commerce platforms, results show that integration of AI and edge computing can reduce latency in customer interactions by up to 70%, while upgrading conversion rates by roughly 30%. These findings emphasize the added value of creating real time customer experience driven sales and customer loyalty leveraging real time customer insights enabled by AI at the edge. This work presents a novel framework that enables scalable, secure hyper personalization in e-commerce to overcome existing limitations in data processing speed and privacy compliance. It offers actionable recommendations for retailers that look to adopt AI driven, edge enabled hyper personalization techniques for enhancing customer engagement and operational efficiency.
Renewable Energy Technologies: Advances and Challenges
Authors: Phanindra Koneru , Bavirisetti Kalyan , Balaji Kotte , Sri Krishna Pydimukkala Devi , Ganesh Dr. KVB
Published: November 2024

The transition from fossil fuels to renewable energy sources is imperative to combat climate change and promote sustainability. This paper explores the recent advancements in renewable energy technologies, focusing on solar, wind, hydro, and bioenergy. It also identifies the challenges these technologies face in terms of economic viability, technological integration, and policy support. Through a comprehensive analysis, this paper underscores the need for coordinated efforts among stakeholders to enhance the adoption of renewable energy. The urgent need to mitigate climate change and adopt sustainable energy practices has propelled the advancement of renewable energy technologies. This paper delves into the recent strides made in solar, wind, hydro, and bioenergy, analysing their potential to revolutionize the global energy landscape. It explores the technical innovations, such as increased photovoltaic cell efficiency and larger, more efficient wind turbines, that have significantly enhanced the performance and cost-effectiveness of these technologies. However, challenges persist in achieving widespread adoption. These include the intermittent nature of renewable energy sources, requiring robust energy storage solutions and grid integration strategies. Additionally, economic factors like initial investment costs and fluctuating energy prices pose hurdles to the financial viability of renewable energy projects. Furthermore, the environmental and social impacts of renewable energy development, such as land use and wildlife habitat disruption, must be carefully considered and mitigated. This includes substantial investments in research and development to further improve renewable energy technologies, supportive government policies and incentives to stimulate market growth, and collaborative efforts among policymakers, industry stakeholders, and researchers to foster innovation and knowledge sharing. By addressing these key issues, we can accelerate the transition to a sustainable energy future powered by renewable resources.
Gambaran self efficacy pada mahasiswa psikogi UNP kampus V Bukittinggi yang mengalami Low Back Pain
Authors: Nirmala Anggraini  , Primanita Rida Yanna
Published: November 2024

Low Back Pain (LBP) merupakan salah satu masalah kesehatan yang sering dialami masyarakat. LBP merupakan nyeri punggung bawah bisa menjadi pemicu utama kecacatan yang mempengaruhi kualitas hidup dan kemampuan seseorang. Penelitian yang dilakukan di Polandia tahun 2018, remaja menderita LBP sebanyak 74,4 %. Sebanyak 82,8 % remaja perempuan lebih sering merasakan nyeri daripada remaja laki-laki yang hanya 64,3 %.  Di Indonesia tahun 2018, diperkirakan sebanyak 7,6%-37% dan 26,74 % penduduk Indonesia yang berumur 15 tahun ke atas dan yang bekerja mengeluhkan bahwa mereka merasakan nyeri di punggung bawah. Berdasarkan hasil wawancara terdapat mahasiswa yang mengalami LBP namun mahasiswa tersebut tidak mau berusaha untuk menyembuhkan LBP padahal mereka tahu cara mengurangi LBP. Salah satu faktor yang mempengaruhi LBP yaitu self efficacy. Self-efficacy dapat memberikan seseorang kemampuan untuk bertahan hidup dan tangguh  dalam menghadapi kesulitan. Metode pada penelitian ini yaitu deskriptif kuantitatif dengan populasi mahasiswa psikologi kampus V UNP. Bertujuan untuk mengetahui gambaran Self-efficacy pada mahasiswa Psikologi Kampus lima Bukittinggi yang menderita Low Back Pain. teknik sampel yang digunakan yaitu non-probability. Hasil penelitian ini yaitu self efficacy pada Mahasiswa Psikologi UNP Kampus V Bukittinggi yang mengalami low back pain berada dalam kategori tinggi dengan persentase 87,5%. Jenis kelamin menjadi salah satu faktor yang mempengaruhi self efficacy, dimana perempuan memiliki self efficacy yang lebih tinggi yaitu 61,54%, dibandingkan laki-laki sebesar 25,96%.
المستفاد من مخاض فكر عمارة الغرب "من عصر النهضة إلى ما بعد الحداثة"
Authors:   جامعة المرقب– كلية الهندسة– قسم العمارة والتخطيط العمراني, البركي بالقاسم يوسف محمد
Published: November 2024

The state of architectural thought in our societies now requires is that diverse reading of these theses and this theorizing about the different architectural orientations in the architecture of the west. An important topic in this context is the influence of community philosophical thought on architectural thought and its product، to ask this research، which says "To what extent can the level of community philosophical thought influence the binary theoretical and applied in architectural and architecture?".
The aim of this research is through a proactive study of the philosophical intellectual depth of various societal theses in the societies of the west "Europe and America"; To know the extent to which it affects the issue of continuity and interruption in the architectural thought، both theoretical and applied، from the Renaissance to Postmodernism.
To achieve this objective; In its first part، the research began to analyze the labour of Western community philosophical dissertations and demonstrate their reflection on architectural theses as a perspective and as an application to reality، In part II، we reached conclusions of the foregoing، the most important of which is to reach out to these motives for periods of continuity and interruption in architectural thought. Let us arrive in part III for several conclusions، the most important of which is the architectural product is the result of a societal philosophicl intellectual struggle in a period of time that has material and immaterial strength، Architecture can be seen as a complement to culture and thought or as equally influential parties، Thus، architecture becomes a symbol of the intellectual premise that tries to create it، through which we can reach the ideology of the prevailing idea in society.
Keywords: Heritage – Employment – Theorizing – application – Modernity.
Morphological and Microsatellite-Based Molecular Characterization of Locally Collected Sugarcane (Saccharum officinarum L.)
Authors:   Institute of Plant Breeding, College of Agriculture and Food Science, University of the Philippines Los Baños, College 4030, Laguna, Philippines, Libayao Carl , Manuel Ma. Carmina ,   Institute of Biological Science, College of Arts and Sciences, University of the Philippines Los Baños, College 4030, Laguna, Philippines, Ocampo Eureka Teresa ,   Institute of Crop Science, College of Agriculture and Food Science, University of the Philippines Los Baños, College 4030, Laguna, Philippines, Lalusin Antonio ,   Institute of Crop Science, College of Agriculture and Food Science, University of the Philippines Los Baños, College 4030, Laguna, Philippines
Published: November 2024

Fifty-three sugarcane accessions from Aklan, Iloilo, Cagayan, Nueva Vizcaya, Isabela, and Bohol were characterized using forty-two morphometric parameters and forty microsatellite markers. Twenty-six morphological characters using the Shannon-Weaver diversity index showed high variability (H’ = > 0.76) and were able to characterize the fifty-three sugarcane accessions. Cluster analysis of morphological traits based on sequential agglomerative hierarchical test and Euclidean distance revealed two groupings at 0.3 coefficient of dissimilarity. The clustering of some accessions was irrespective of their geographical origin indicating a high degree of phenotypic similarity in some accessions. Out of the forty microsatellite markers, twenty-five (63%) have a PIC value greater than 0.5 with Sach 53 showing the highest at 0.89. This implies that these markers are suitable for sugarcane genetic diversity studies as they can detect a high number of discernable alleles. Molecular cluster analysis generated using Unweighted Pair Group Method with Arithmetic Mean (UPGMA) and Jaccard distance showed two clusters at 0.4 coefficient of dissimilarity. In cluster I, twenty-one accessions from Aklan and Iloilo grouped indicating genetic similarity. Aklan and Iloilo provinces are both located in the same geographic island in Western Visayas, hence, the observed grouping in cluster I. On the other hand, thirty-two sugarcane accessions from Northern Luzon (Cagayan, Nueva Vizcaya, and Isabela), Iloilo, Aklan, and Bohol were grouped in cluster II. The observed clustering of accessions from different regions implies the extensive distribution of sugarcane germplasm to the different parts of the Philippines.
Postharvest Salicylic Acid and Melatonin Dipping Delay Ripening and Improve Quality of ‘Sensation’ Mangoes
Authors:   Department of Arid land Agriculture, Faculty of Meteorology, Environment and Arid land Agriculture, King Abdulaziz University, Jeddah, Saudi Arabia, Awad Mohamed ,   Pomology Department, Faculty of Agriculture, Mansoura University, El-Mansoura/Egypt, Al-Qurashi Adel ,   Department of Arid land Agriculture, Faculty of Meteorology, Environment and Arid land Agriculture, King Abdulaziz University, Jeddah, Saudi Arabia
Published: November 2024

Freshly harvested mature-green ‘Sensation’ mangoes were dipped for 10 min in 2 mM salicylic acid (SA) and 0.2 mM melatonin (MT) alone or in combination and stored at 23±1°C and 60–70%RH. SA or MT delayed ripening measured as higher green peel color (lower a* values), firmness, titratable acidity (TA) and membrane stability index (MSI) and lower weight loss, total soluble solids (TSS), TSS/TA ratio and hydrolytic enzyme activities (polygalacturonase, xylanase and α-amylase) compared to that of untreated fruit. Total phenolic content (TPC) in peel of treated fruit increased with fluctuations during ripening and was higher than the control. In pulp, TPC decreased up to 6 days but increased thereafter, and was higher in treated fruit than the control. Total flavonoid content (TFC) in the peel decreased while that in the pulp increased with fluctuations during ripening and was higher in treated fruit than the control. Vitamin C content decreased during ripening and was not affected by the treatments. DPPH radical scavenging capacity (RSC) in peel decreased during ripening and was higher in treated fruit than the control. However, RSC in pulp increased during ripening and was not affected by treatments, except for SA plus MT treatment that gave higher RSC than the control after 6 and 10 days. Polyphenoloxidase (PPO) activity increased during ripening and was lower in treated fruit than the control. Peroxidase (POD) activity increased during ripening and was higher in treated fruit than the control. SA and MT combination treatment provided no additional positive effects on most parameters. It is concluded that postharvest dipping in 2 mM SA or 0.2 mM MT delayed ripening and improved quality of ‘Sensation’ mangoes via inhibiting hydrolytic enzymes and enhancing antioxidant system of fruit and are suggested as natural alternative to synthetic chemicals.
Functional near-infrared spectroscopy study of hemodynamic in the prefrontal and motor cortices and its implications for endurance capacity
Authors: Liang Zhiqiang
Published: November 2024

This study investigates the primary cortical areas that influence endurance capacity in humans by monitoring cerebral hemodynamics in the prefrontal and motor cortices during endurance exercise. Participants engaged in incremental load endurance exercise while equipped with a functional near-infrared spectroscopy to assess cortical activity. Hemodynamic in the prefrontal and motor cortices were continuously monitored, with a particular emphasis on cortical activation at both the onset and termination of exercise, as well as their relationships with exercise duration and other cortical regions. Results showed that both the prefrontal and motor cortices exhibited significant activation during the onset and termination of exercise, with activation intensity and areas increasing in response to elevated exercise loads. Notably, cortical activation in these cortices at the onset of exercise did not show a significant correlation with exercise duration. However, activations in specific aeras of the motor cortex-FC1h, FC2h, C1h, and C2h-at the termination of exercise were significantly correlated with endurance duration and showed extensive interconnections with other areas in both the prefrontal and motor cortices. These results suggest that FC1h, FC2h, C1h, and C2h in the motor cortex might play a crucial role in regulating endurance capacity. Enhancing the functionality of these cortical areas might contribute to further improvements in endurance performance.
The promoting effect of biomechanics-based optimization strategies for preschool sports on mental health
Authors: Han Zengxia , Wang Jing
Published: November 2024

Background: Early childhood is crucial for physical and mental development. Incorporating sports into preschool education fosters motor skills but also promotes emotional and psychological well-being. Traditional sports programs often focus on generalized physical activities, neglecting biomechanics to optimize movement efficiency and reduce injury risks. A holistic approach combining biomechanics with mental health promotion is needed. Aim: This study investigates the impact of biomechanics-based optimization strategies in preschool sports and their effects on mental health. Methods: The research involved 150 preschool children divided into two groups: One participating in a biomechanics-based sports program (experimental group) and the other in a conventional sports curriculum (control group) based on survey. The biomechanics-based program included an assessment of body biomechanics and movement efficiency, alongside pedagogical methods designed to enhance physical and mental development. SPSS software was used to analyze covariance (ANCOVA), independent samples t-tests, paired samples t-tests, chi-square tests, and regression analysis to evaluate the efficiency of the biomechanics-based program and its influence on the physical and mental health of preschool children. Results: Results showed significant physical improvements, including enhanced head angle, muscle strength, spinal flexibility, and balance control. The biomechanics-based program significantly improved children’s physical and mental health metrics, particularly motor skills, balance, and emotional regulation. These improvements contribute to better mental health outcomes by fostering a positive self-image (PSI), enhancing confidence (EC), and promoting emotional well-being (PEW). Conclusion: The study emphasizes the importance of integrating biomechanics-based strategies into preschool sports programs to support both physical and mental development.
The effect of fluconazole combined with amphotericin B on highly toxic miR-15b and TGF-β1 of cronobacter in neonates
Authors: Xu Yafei , Li Hui
Published: November 2024

Objective: To analyze the effects of fluconazole combined with amphotericin B on the levels of miR-15b and transforming growth factor-β1 in patients with cronobacter in neonates. Methods: Using the random number table method, twenty-eight patients who were admitted to our hospital between January 2018 and January 2021 with cronobacter pneumonia were chosen and split into two groups: the control group and the observation group. For 14 days, they received either fluconazole with amphotericin B or amphotericin B alone. The pulmonary function forced expiratory volume in one second (FEV1) and forced vital (FORCED vital) of the two groups were observed and recorded Capacity (FVC), forced expiratory volume/forced vital volume in one second/orced vital Capacity, FEV1/FVC), procalcitonin (PCT), soluble receptor expressed on myeloid (Triggering receptor expressed on myeloid) Cells-1, StreM-1), Mir-15b and TGF-β1, and the clinical efficacy was evaluated. Results: After treatment, the levels of FEV1, FVC and FEV1/FVC in patients were increased, and the levels of FEV1, FVC and FEV1/FVC in observation group were higher than those in control group (P < 0.05). After treatment, the levels of PCT and sTREM-1 were decreased, while the levels of miR-15b and TGF-β1 were increased. Compared with the control group, the levels of PCT and TREM-1 were lower in the observation group, while the levels of miR-15b and TGF-β1 were higher (P < 0.05). The total effective rate of observation group (92.86%) was significantly higher than that of control group (57.14%), the difference was statistically significant (P < 0.05). Conclusion: Fluconazole plus amphotericin B has demonstrated clinical efficacy in treating patients with cronobacter pneumonia in neonates. It can effectively improve the inflammatory state of the body, miR-15b, and TGF-β1, as well as aid in improving lung function with fewer side effects and high safety.
Referral Time for Diabetic Retinopathy Screening and Impact on the Visual Acuity of Patients in a Tertiary Hospital
Authors: Uraruen Sinpana , Chantarasorn Yodpong
Published: November 2024

OBJECTIVE: To evaluate the referral time for the screening of diabetic retinopathy (DR) from the initial diagnosis of diabetes to retinal examination. We also compared visual results among groups screened at various duration of referral time.METHODS: This cross-sectional study was conducted retrospectively from medical records for the poorer-seeing eyes of 100 patients with type 2 diabetes from January 2021 to December 2022 at the tertiary eye center. Patients were classified based on the time duration from the initial diagnosis of diabetes to retinal examination or imaging. Visual acuity (VA) and DR stages categorized by the period of referral time were compared among each group.RESULTS: Seventy-five patients (75%) took > 2 months from the first diagnosis of diabetes to DR screening performed by an ophthalmologist. Twenty-three patients (23%) were diagnosed with DR at the first ophthalmic visit; among these, 16 had a referral time of > 2 months. Twelve patients were diagnosed with vision-threatening DR; six of these had diabetic macular edema. The receiver operating characteristic (ROC) curve analysis indicates that patients receiving ophthalmic examination within 91 days from the diagnosis of diabetes likely maintain a best-corrected VA of ≥ 20/50. This recommended period of referral time yielded an area under the ROC curve, sensitivity, and specificity of 70.63%, 61.90%, and 83.33%, respectively.CONCLUSION: In clinical practice, a prolonged period for the first DR screening is relatively common and may result in more patients with vision-threatening DR. Proactive and systematic work should be undertaken to create patient awareness on the importance of detection of asymptomatic and early-stage DR to prevent irreversible visual loss.
Synergistic UAV Motion: A Comprehensive Review on Advancing Multi-Agent Coordination
Authors: Abro Ghulam E Mustafa , Ali Zain Anwar , Masood Rana Javed
Published: November 2024

Collective motion has been a pivotal area of research, especially due to its substantial importance in Unmanned Aerial Vehicle (UAV) systems for several purposes, including path planning, formation control, and trajectory tracking. UAVs significantly enhance coordination, flexibility, and operational efficiency in practical applications such as search-and-rescue operations, environmental monitoring, and smart city construction. Notwithstanding the progress in UAV technology, significant problems persist, especially in attaining dependable and effective coordination in intricate, dynamic, and unexpected settings. This study offers a comprehensive examination of the fundamental principles, models, and tactics employed to comprehend and regulate collective motion in UAV systems. This paper methodically analyses recent breakthroughs, exposes deficiencies in existing approaches, and emphasises case studies demonstrating the practical application of collective motion. The survey examines the substantial practical effects of collective motion on improving UAV operations, emphasizing scalability, resilience, and adaptability. This review is significant for its potential to inform future research and practical applications. It seeks to provide a systematic framework for the advancement of more resilient and scalable UAV collaboration models, aiming to tackle the ongoing challenges in the domain. The insights offered are essential for academics and practitioners aiming to enhance UAV collaboration in dynamic environments, facilitating the development of more sophisticated, flexible, and mission-resilient multi-UAV systems. This study is set to significantly advance UAV technology, having extensive ramifications for several industries.
Investigating the Role of B Cell Receptors in Pathogen Recognition and Immune Response Activation: Implications for Infection Control and Therapeutic Development
Authors: Özalp Selin
Published: November 2024

B cell receptors (BCRs) are critical components of the adaptive immune system, enabling precise pathogen recognition and the activation of immune responses. This research examines the molecular and genetic mechanisms underlying BCR function, focusing on their role in detecting, binding, and neutralizing infectious agents. By exploring antigen-BCR interactions, we aim to elucidate how BCRs achieve their remarkable specificity and affinity, ultimately shaping the strength and duration of immune responses. Through advanced immunological assays, flow cytometry, and bioinformatics, this study characterizes the diversity of BCR expression across various infectious models. Genetic processes such as somatic hypermutation and clonal selection are analyzed to understand how BCR repertoires adapt to rapidly evolving pathogens. Predictive models developed using machine learning identify biomarkers within BCR pathways, providing insights into acute infections, chronic diseases, and autoimmune conditions. The findings highlight variations in BCR function that influence immune resilience and susceptibility to infections. These insights inform vaccine development, antibody engineering, and therapeutic strategies targeting BCR pathways. This research underscores the potential of BCRs as biomarkers and therapeutic targets, paving the way for innovative approaches in infection control and immune modulation, ultimately advancing precision medicine and adaptive immunity research.
Automatic Passenger Counting System on Public Buses Using CNN YOLOv8 Model for Passenger Capacity Optimization
Authors: Ari Dian Prastyo  , Sharfina Andzani Minhalina  , Surya Agung  , Denty Nirwana Bintang  , Muhammad Yordi Septian  , Endang Purnama Giri  , Gema Parasti Mindara
Published: November 2024

This study presents the development of an automatic passenger counting system for public buses using YOLOv8 based on Convolutional Neural Networks (CNN). The system detects and counts passengers in real-time to optimize bus capacity and enhance operational efficiency. Results indicate that the system achieves high accuracy in the front camera view (confidence score of 0.82). However, in the rear camera view the accuracy slightly decreases (confidence score of 0.76) due to object overlap, emphasizing the importance of proper camera placement. The system offers potential improvements in bus capacity management, reduced operational costs, and enhanced passenger comfort. These findings contribute to advancing smarter and more efficient public transportation systems.
Towards enhanced care : Exploring the implementation of novel diagnostics for acute respiratory tract infections in European primary care
Authors:   , Hoste Melanie E.
Published: November 2024

This thesis assesses European primary care as a setting for implementing novel diagnostics for managing acute respiratory tract infections. Through an in-depth examination of perspectives from key stakeholders, including clinicians utilising diagnostics, patients receiving care during the COVID-19 pandemic, and others involved in the implementation process of novel diagnostics in Europe, this thesis aims to provide a rich narrative of stakeholders’ experiences and to capture the multi-level phenomenon of implementing an innovation.
Trace Metal Levels in Seawater, Suspended Particulate Matter and Sediment in Mersin Bay, Turkey
Authors: Yılmaz Doruk
Published: November 2024

The concentrations and distributions of trace metals in surface sediment, water and suspended particulate matter (SPM) in coastal area of Mersin Bay were studied to determined the anthropogenic inputs from surrounding activities. Elevated zinc levels (275 ppm) represent the trace metal with the highest concentration, as measured in suspended particulate matter samples collected from the Kazanlı and Karaduvar areas. The high concentrations are associated with terrestrial inputs from the anthropogenic (domestic +industrial) sources. An important observation is that increasing concentrations are found in dissolved phase, sediment and particulate phase, respectively. But this is not the case for Cr which is higher in sediment. This is related to intense activity of chromium processing plant working for many years. Moreover, Cd and Cr concentrations in surface sediments are above the shale average. Heavy metal concentrations in surface sediments are Cr>Zn>Cu>Pb>Cd, respectively. The elevated copper level relative to cadmium in surface sediments is likely attributable to the higher stability of surface complexes with clay minerals, which constitute the primary components of the sediments. Adsorption of zinc to iron and manganese oxide compounds in the sediment is a possible explanation for the high amounts of zinc that were found in the sediments. The estimated index values (enrichment factor, geoacumulation index and pollution load index) indicated widespread contamination of Cr and Cd in Mersin Bay. The origins of these trace metals in the sediments were caused by human activity, and the region was categorized as a moderately severely polluted area.
Testing of Property Flood Resilience: What have we learnt?
Authors: Ramsbottom David , Tagg Andrew
Published: November 2024

Flood protection of properties has traditionally been provided by engineered flood defences. In recent years, however, there has been an increase in interest in flood protection for individual properties. This has taken two forms which together are referred to as property flood resilience (PFR): ‘resistance’, where flood water is prevented from entering a property, and ‘recoverability’, where flood water is allowed to enter a property but the damage is minimised in order to permit rapid recovery after a flood. Other methods for protecting properties including traditional flood defences are also discussed in order to provide an overview of the methods available and indicate where PFR fits in. The importance of PFR in flood management both in the UK and internationally is likely to grow as PFR is increasingly being considered as an important option to reduce flood risk for individual properties. Many different types of flood resistance products have been developed in order to keep flood water out of houses. Proof was needed that these products would be effective during a flood and the British Standards Institution (BSI) worked with HR Wallingford, the Environment Agency and product manufacturers to develop methods and standards for product testing. A product testing rig was constructed at HR Wallingford. Initially a large number of products were tested but the number has reduced as successful products have become established. In addition, some manufacturers have developed their own testing facilities. The tests have demonstrated that resistance products can protect properties provided that they are correctly installed, not overtopped by flood water, and water does not enter the properties by other routes. In addition, tests have been carried out to assess the performance of building materials under flood conditions both for flood resistance and flood recoverability. Flood product testing has evolved rapidly in recent years in the UK and other countries. This paper therefore does not claim to provide a comprehensive overview and includes some personal reflections and opinions based on the authors’ experience.
USO DA RITALINA (METILFENIDATO) E VENVANSE (DIMESILATO DE LISDEXANFETAMINA) NO TRATAMENTO DO TDAH
Authors: César Sanchez Leirião Bruno , Benito Caricilli Lorenzo , Silva Rodrigues Giovanna , Dias da Silva Valter
Published: November 2024

Para a maioria dos indivíduos, os medicamentos estimulantes são uma forma segura e eficaz de aliviar os sintomas do Transtorno de Déficit de Atenção com hiperatividade (TDAH). Assim, como os óculos ajudam as pessoas a focarem os olhos para ver, esses medicamentos ajudam os pacientes com TDAH a concentrar melhor seus pensamentos e a ignorar as possíveis distrações. Isso os torna mais capazes de prestar atenção e controlar seu comportamento. Estudos mostram que aproximadamente 80% dos pacientes com TDAH tratados com estimulantes melhoram muito quando a medicação e a dosagem apropriadas são determinadas. Partindo dessa premissa, vislumbra-se a importância de avaliar a eficácia dos principais medicamentos utilizados no Brasil nos últimos anos, o metilfenidato e a lisdexanfetamina no tratamento de portadores de TDAH, entendendo o mecanismo de ação desses fármacos, sua eficácia e possíveis interações. A revisão de literatura foi realizada por meio de pesquisa bibliográfica em bases acadêmicas e científicas entre elas: Biblioteca Virtual em Saúde (BVS), LILACS, PubMed/MEDLINE, Google Acadêmico, Scielo, ScienceDirect, Pepsic, Associação Brasileira de Medicina e Associação Brasileira do Déficit de Atenção, o período compreendido das publicações foram os últimos 15 anos, utilizou-se os seguintes descritores: transtornos do déficit de atenção, hiperatividade, Ritalina, metilfenidato, Venvase, Lisdexanfetamina, tratamento do TDAH. O intuito principal do trabalho era tornar-se base de conhecimento para profissionais da saúde e pacientes com TDAH.
The Analysis of Rendering Slang Expressions in Audiovisual Translation
Authors: Alimova Iroda
Published: November 2024

Abstract- Audiovisual translation has become a global domain in which translators of dubbing and subtitling translate and transfer culture from source languages into target languages. Subtitling and dubbing have always been affected by cultural elements. This especially can be seen when the culture of two languages has less comparable moments. Therefore, translators have to face such cultural differences and try to search for equivalences or for other translating strategies in order to come to desired result. The translation of cultural and linguistic elements such as realia, dialects, idiolects, sociolects, slang and other forms of culture related forms make the work of any translator tough and complex. The analysis of slang expressions is difficult due to their translation problems arising because of nonequivalence. This study investigates how English slang is translated in the Uzbek dubbing version in the film “The covenant” (2023) looking at how the meaning and message might be transferred. The article puts two tasks to accomplish within the research. The first purpose of this research is the analysis of slang expressions taken from American movies shot during 2023-2024 mainly on the basis of “The covenant” (2023). Next the research explores the translation strategies used in the movie “the covenant” by the translators in dubbed version.
Analysis of Theoretical Views on the Concept of Corruption and Crimes Related to Corruption in the Criminal Code of the Republic of Uzbekistan
Authors: Takhirov Farhod , Usmanova Muborak , Zakurlaev Abdulmuttal , Nurmukhammedova Gozalkhon
Published: November 2024

Abstract:
Corruption remains one of the most critical challenges for governance, economic development, and social stability in many countries, including Uzbekistan. This article offers a comprehensive analysis of the theoretical perspectives on the concept of corruption and the legal framework surrounding crimes related to corruption under the Criminal Code of the Republic of Uzbekistan. By examining both international and national definitions and classifications of corruption, as well as recent legal reforms, this paper aims to contribute to a deeper understanding of how corruption is treated in Uzbek legal theory and practice. The analysis also highlights key legal provisions, judicial approaches, and challenges in combating corruption, providing a basis for future reforms and enhanced anti-corruption strategies.
HABILIDADES MOTORAS E FUNCIONALIDADE CORPORAL NA SAÚDE EQUALIDADE DE VIDA EM IDOSOS PRATICANTES DE EXERCÍCIOS FÍSICOS
Authors: Silva Dárllison Hudson Pereira Da , Cantalice Maria Vitoria Silva , Carvalho Leyla Regis De Meneses Sousa
Published: November 2024

Introduction: Aging is a natural and progressive process responsible for several physiological, morphological, functional, biochemical and psychological changes, compromising their autonomy, this process is accompanied by structural and functional changes of the body and mind, and is also associated with cognitive decline that can affect the health and quality of life of the elderly. Objective: To verify motor skills in body functionality and health and quality of life in elderly practitioners of physical exercises. Methods: This is an integrative literature review, carried out in the following databases: Virtual Health Library (VHL), Bireme, Pubmed, Lilacs, Medline, Scientific Electronic Library Online (SciELO). Using the following descriptors alone and/or in combination: Physical exercise and motor skills in the elderly, Physical exercise and motor coordination in the elderly; Physical exercise and balance in the elderly; Physical exercise and functionality in the elderly; Physical exercise, motor coordination and functionality in the elderly; Physical exercise, balance and functionality in the elderly; Physical exercise and quality of life in the elderly. Results: The data showed that maintaining an active lifestyle is essential for the development of motor skills that consequently affects the autonomy, functionality and quality of life of the elderly. Considerations: An active lifestyle stimulates and maintains motor skills, which are fundamental mechanisms for maintaining the functional independence of the elderly. As for the limitations of the research, the theme focused on motor coordination proved to be quite scarce, and studies that deal with the study of skills in a more specific way are suggested.
ANÁLISE DO USO DO CANABIDIOL NO TRATAMENTO DE SÍNDROMES EPILÉPTICAS: UMA REVISÃO DE LITERATURA
Authors: Queiroz Hellen de Araújo , Meneses Brenda de Moura , Lima Alécio Galvão , Cerqueira Anna Beatriz Fortes de , Castro Antônio Gabriel dos Santos , Coimbra Isabela da Silva , Bonfim Luana Kaira Lopes do , Pires Luís Octávio Furtado Azevedo de Melo , Sampaio Maria Heloise Rosendo , Andrade Ana Rachel Oliveira de , Júnior José Lopes Pereira , Campelo Vanessa Meneses de Brito
Published: November 2024

A epilepsia é clinicamente definida como uma síndrome de crises recorrentes não provocadas ou como uma crise com evidência de um risco aumentado de recorrência de crises acima de 60% nos próximos 10 anos. Não é uma doença única, mas sim um conjunto de distúrbios neurológicos que partilham uma predisposição duradoura para gerar crises epilépticas. As convulsões, embora sejam o sintoma principal, não são o único aspecto da epilepsia que afeta a qualidade de vida do paciente. Infelizmente, até 30% dos pacientes com epilepsia não alcançam a liberdade das crises com dois anticonvulsivantes adequadamente escolhidos, portanto, devem ser considerados resistentes aos medicamentos. As convulsões, bem como os efeitos colaterais dos medicamentos anticonvulsivantes, as comorbidades e as consequências sociais das convulsões levam a uma perda significativa na qualidade de vida das pessoas afetadas. Assim, vem sendo discutida a utilização do canabidiol (CBD) no tratamento da epilepsia. Dessa forma, urge a necessidade de discutir acerca da importância do CBD no que diz respeito ao tratamento das síndromes epilépticas, bem como o desenvolvimento de mais estudos acerca da sua eficácia e dos mecanismos pelos quais o CBD age nesse controle. Assim, esse estudo objetiva analisar, por meio de uma revisão de literatura, o impacto da utilização do canabidiol no tratamento de síndromes epilépticas.
The story of Desdemona: psychotherapy conducted with a PCP approach
Authors: Giliberto Massimo
Published: November 2024

This presentation is an exploration of a client-therapist relationship and the story of their experiences in the context of psychotherapy. Through the case of a female victim of domestic violence – who repeatedly chose violent men as partners – it is an investigation into how, using Personal Construct Psychology, the therapist understands his client and how this understanding channels new experiments in the psychotherapy room and in the life of the client. It also explores how these new experiences contribute to changing the client’s identity constructs, helping her to change from the role of ‘victim’ to taking her own life back.
Arkeolojide Anıtsallık Ve Karia’da Anıtsal Mezar Mimarisinin Gelişimi Üzerine Bir Değerlendirme
Authors: Söğüt Ahmet
Published: November 2024

İnsanlık tarihinin belki de en önemli olgusu kişinin varlığı ve ölümüdür. İnsan, kaybedilenleri anma ve varlığının izlerini bu dünyada bırakma aracı olarak anıtlar inşa etmiştir. Anıt, tarihte yaşanmış büyük olayları, önemli kişilerin hatıralarını sonraki kuşaklara aktarmak için yapılmış olsa da, esas olarak insanın dünyada bir iz bırakma çabası olarak nitelendirilmektedir. Anıtlar, küçük bir mezar taşından, firavunların büyük ölçekli mezarlarına, dikili taşlardan, tarihteki önemli kişilerin kahramanlık hikâyelerinin tasvir edildiği heykellere, insanın var olma, hatırlanma ve iz bırakma güdüsünü temsil etmesi gibi amaçlarla yapılmıştır. Anıtsallık kavramının kullanımı, mimaride, sanat tarihinde özellikle arkeoloji gibi birçok akademik disiplinde yaygın olarak bulunmaktadır. Ancak arkeoloji literatüründe anıtsallığın tanımının tam olarak yapılmamış olması bu kavramın esasen mimarlık disiplini içerisinde değerlendirilmesine yol açmıştır. Bu nedenle bu çalışmada öncelikli olarak anıt/anıtsallık kavramı üzerinde durulmuş ve arkeolojide anıtsallığa yaklaşım irdelenmiştir. Bu çalışma içerisinde yer alan bir diğer bölümde ise; Karia Bölgesi sınırları içerisinde yer alan yerleşimlerdeki anıtsal mezar mimarisinin, MÖ 6. yüzyıldan dan başlayarak MS 2. yüzyıla kadar, gelişimi ortaya koyulmaya çalışılmıştır.
Measuring the Effects of Financial and Economic Shocks on Some Macro Variables in Some Developing Countries
Authors: Muaamal Hussein Jwesim  , Ghufran Shallal Mohammed
Published: November 2024

This research attempted to analyze the impact of financial and economic shocks in a number of developing countries that are similar in terms of the size of the economy and the diversity of its economic structure, as well as the similarity in the quality of the exchange systems used to demonstrate the extent of the monetary authorities’ ability to target inflation in light of the occurrence of shocks of various types and forms during the research period, in addition to This is an indication of the extent of the diversity of the economy and its connection to those shocks, as the oil sector constitutes a large portion of the gross domestic product of the countries of the research sample, with this being lower for the Emirati economy, and this matter made the Iraqi economy to be more affected by the economic crises and shocks that occurred during the period of the study compared to other economies. Saudi Arabia and the Emirates, where the Saudi economy comes in second place in terms of being affected by these shocks, followed by the Emirati economy, which had the least impact. The research variables (inflation, public revenues, and gross domestic product) were also closely linked to the occurrence of both positive and negative financial and economic shocks. When countries face a positive economic shock, the economic situation in the sample countries improves, and the research variables tend to increase, and vice versa when those countries face a shock. Negative, taking into account the varying rates of impact and response, especially with the UAE economy.
The Role of the Cash Flow Statement in Enhancing the Quality of Financial Reporting in the General Tax Authority : An Applied Study
Authors: Hala Abdul Ameer Dhahir  , Ahmed Rahi Abed  , Nuha Aadi Abd Ali
Published: November 2024

The percentage of Adequacy Flows Cash Operational and indicator Activity Operational and revenue on assets from the flow are two examples of cash flow events that help improve the quality of financial reporting. The research attempts to address the theoretical framework of the cash flow statement. According to the following premise, cash flow metrics have the potential to improve the quality of financial reporting. The Iraqi General Tax Authority for 2022 and 2023 serves as the study sample. The study came to several results, chief among them being that the cash flow list can offer Since these measures express the continuity of cash flows for the research sample, they would help improve the quality of financial reporting by measuring the quality of the sample's profits in a way that improves performance and is consistent with the variables supplementary the contemporary business environment for the research sample related to the Iraqi General Tax Authority.