bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan Self Control dengan Smartphone Addiction pada Siswa Sma X di Kabupaten Bandung Barat
Authors: Fadila Zulfa Amara  , Wahyudi Hedi
Published: March 2024

Abstract. The rapid development of technology affects the life of education, work, and in everyday life. One technology that is growing very quickly is the smartphone, which is part and not missed, especially among students. Excessive use of smartphones can cause dependence to the end of daily life. This can be overcome if you have self-control, the reality is that students have not been able to overcome and carry out tasks as students so as not to experience dependence. The purpose of this study was to determine the relationship between self-control and smartphone addiction in students of SMA X Bandung Barat. The method used was quantitative and correlational research design with a total subject of 300 students. The sampling technique used is Purposive Sampling with an analysis technique that tests the Spearman Rank Correlation. Data collection in this study used the Smartphone Addiction Proneness Scale (SAPS) questionnaire from Kim et al (2014) and Self Control (Averill, 1973). The results showed that there was a significant negative relationship between Smartphone Addiction and Self Control in SMA X students in Kabupaten Bandung Barat shown by Spearman correlation values of r = - 0.706 and p = 0.000 (p < 0.05). There is a relationship between self-control and smartphone addiction in students of SMA X Kabupaten Bandung Barat.

Abstrak. Semakin pesat perkembangan teknologi berpengaruh dalam kehidupan pendidikan, pekerjaan, maupun dalam kehidupan sehari-hari. Salah satu teknologi yang berkembang sangat cepat yaitu smartphone, yang menjadi bagian dan tak terlewatkan khusunya di kalangan siswa. Penggunaan smartphone yang berlebihan dapat menyebabkan ketergantungan hingga berdapak pada kehidupan sehari-hari. Hal tersebut dapat diatasi jika memiliki adanya self control, realitasnya siswa belum mampu mengatasi dan menjalankan tugas sebagai pelajar agar tidak mengalami ketergantungan. Tujuan dari penelitian ini yaitu untuk mengetahui hubungan self control dengan smartphone addiction pada siswa SMA X Kabupaten Bandung Barat. Metode yang digunakan adalah kuantitatif dan desain penelitian korelasional dengan jumlah subjek 300 siswa. Teknik Sampling yang digunakan Purposive Sampling dengan teknik analisis yang Uji Korelasi Rank Spearman. Pengumpulan data dalam penelitian ini menggunakan kusioner Smartphone Addiction Proneness Scale (SAPS) dari Kim et al (2014) dan Self Control (Averill, 1973). Hasil penelitian menunjukkan bahwa ada hubungan negatif yang signifikan antara antara Smartphone Addiction dan Self Control pada siswa SMA X di Kabupaten Bandung Barat ditunjukkan dengan nilai korelasi Spearman sebesar r = - 0.706 dan p = 0.000 (p<0.05). Terdapat hubungan antara self control dengan smartphone addiction pada siswa SMA X Kabupaten Bandung Barat.
Impactos da pandemia da covid-19 na saúde física e mental de estudantes de medicina
Authors: Rocha Larissa Costa Dos Santos Oliveira , Paim Pedro Eduardo Rodrigues Lavigne , Sálvio Neto Raymundo , Silva Raian Borges , Tourinho Luciano de Oliveira Souza
Published: March 2024

A pandemia do COVID-19 modificou de forma significativa a rotina da população mundial, principalmente no que diz respeito a adoção de novos hábitos necessários para prevenir a disseminação do vírus. No entanto, alguns comportamentos prejudiciais à saúde acabaram sendo adotados particularmente como consequência dos efeitos do isolamento sobre a saúde mental. Dessa forma, este projeto de pesquisa objetivou avaliar os possíveis impactos da pandemia na saúde física e mental de estudantes de medicina, tomando por base as alterações no modo de vida decorrentes das restrições ao convívio social, da suspensão das aulas presenciais e das dificuldades de continuidade dos estudos remotamente, considerando os registros de casos de infecção, perda de emprego e redução de salários no âmbito familiar, além das diferenças no comportamento segundo sexo, raça e condição social. O presente estudo é de caráter quantitativo observacional e transversal. Trata-se de uma revisão bibliográfica, no qual foram analisados artigos disponíveis na base de dados da Biblioteca Virtual em Saúde, Scielo e Pubmed. Como critérios de inclusão, foram analisados artigos completos, publicados de 2018 a 2022 e possuir como assunto principal a saúde mental, universitários, estudantes de medicina, medicina, ansiedade, pandemia e saúde. Excluiu-se artigos repetidos ou com fuga do tema. Este estudo tem como objetivo analisar artigos publicados de 2018 até 2022 sobre o impacto da pandemia na saúde física e mental dos estudantes de medicina. A saúde física e mental do acadêmico de medicina constitui-se como importante fator de preocupação tanto no aspecto de saúde pública quanto no aspecto educativo, por isso, é imprescindível que sejam pensadas iniciativas para melhorar a qualidade de vida e de estudo desta população.
Hipertensão na terceira idade: uma revisão da literatura sobre causas e dificuldades no tratamento
Authors: Silva Júlia de Sá , Tannus Lázaro Silva , Lemos Maria Alice do Carmo de , Santos Maria Luiza Soares Rocha , Oliveira Évelin Santos
Published: March 2024

A Hipertensão Arterial (HA) é uma das doenças crônicas não transmissíveis que mais afetam a população brasileira, principalmente a população idosa (acima de 60 anos), além de ser a causa mais comum da ocorrência de doenças cardiovasculares, já que se configura como um fator de risco para a aterosclerose, doença coronária e mortalidade associada ao acidente vascular encefálico. Objetivos: o presente estudo objetiva delimitar as principais causas e a gravidade da Hipertensão Arterial em idosos e identificar o nível de compreensão da população sobre a doença e o seu tratamento. Metodologia: Este trabalho visa, por meio de uma revisão literária sistêmica realizar uma busca de Artigos nas bases de dados: Scientific Electronic Library Online (Scielo), PubMed, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Medical Literature Analysis and Retrieval System Online (MEDLINE) a partir dos seguintes descritores: hipertensão arterial e idosos, afim de, identificar fatores que dificultam a adesão do tratamento e acompanhar a eficácia do uso de fármacos. Resultados e discussões: A partir da análise feita, é possível inferir que as causas mais recorrentes de HAS é tabagismo, colesterol e diabetes e, além disso, menciona-se que as condições socioeconômicas, o gênero e a baixa escolaridade são fatores que dificultam a adesão ao tratamento. Conclusão: Dessa forma, ao agregar informações acerca da HA, suas causas mais recorrentes e problemas de adesão ao tratamento é possível traçar medidas mais efetivas para reduzir o seu índice de incidência e melhorar o bem-estar dos acometidos pela doença.
Avaliação dos principais motivos de desistência do tratamento da tuberculose: uma revisão sistemática
Authors: Ferreira Brenner Marcus Alves , Magalhães José Ricardo Carvalho , Brito Moarah Gabrielly Souza , Santos Thiago Froeder , Oliveira Évelin Santos , Moraes Flávia de Lima Paraventi
Published: March 2024

A Tuberculose (TB) é uma infecção crônica e progressiva causada pelo Mycobacterium tuberculosis, afetando mais comumente os pulmões. O tratamento para a doença pode ser eficaz, entretanto muitas vezes o mesmo não é concluído com êxito e a reincidência torna-se inevitável. Além disso, está entre as principais causas de morte no mundo, tratando-se de um problema de saúde pública. Objetivo. Conhecer, a partir das publicações científicas, os fatores que contribuem para a desistência ao tratamento da tuberculose. Metodologia. Trata-se de uma revisão sistemática da literatura, em que a busca na literatura foi realizada por meio do acesso online ao portal da Biblioteca Virtual em Saúde - BVS, nas seguintes bases de dados: Medical Literature Analysis and Retrieval System Online (MEDLINE), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Bases de Dados de Enfermagem (BDENF), utilizando-se os descritores “tuberculose” AND “desistência ao tratamento”, no período de agosto a setembro de 2022. Resultados e Discussão. Os artigos em estudos publicados entre janeiro de 2012 e setembro de 2022 evidenciaram que os principais entraves à continuidade do tratamento da tuberculose estão relacionados a fatores psicossociais, biológicos, econômicos e culturais, sendo mais enfatizados a baixa escolaridade, o uso excessivo de álcool e ser do sexo masculino. Conclusão. Através da análise dos estudos, percebeu-se que o vínculo da equipe de saúde e o paciente são fundamentais para que os profissionais possam intervir de forma individualizada nas causas que podem levar a um insucesso no tratamento.
A aporofobia social e o Direito à Saúde da população de rua no período de pandemia do Covid-19: Desafios necropolíticos para a saúde plena e integral
Authors: Sotero Ana Paula da Silva , Tourinho Luciano de Oliveira Souza
Published: March 2024

O presente estudo tem por objetivo analisar os efeitos da aporofobia nas práticas necropolíticas de exclusão social da população de rua no acesso ao direito sanitário no enfrentamento ao Covid-19. Verifica-se que, diante da ingerência do sistema de saúde para toda a população, a desigualdade do acesso ao direito sanitário tem se fortalecido a partir da incorporação da aporofobia como prática necropolítica para determinar quem deve ter acesso à saúde plena e integral e quem está destinado a viver à margem desse direito. Nessa linha de intelecção, o estudo tem por objetivo analisar a influência da aporofobia no contexto de enfrentamento ao Covid-19 pela população de rua e os entraves necropolíticos da efetividade do direito à saúde plena e integral aos povos que estão vivendo nas ruas. Para delinear a presente pesquisa, utilizamos uma metodologia bibliográfica, de natureza exploratória e documental acerca da aporofobia, da necropolítica e dos dados de contaminação da Covid-19 pela população de rua. Em situação de pandemia do coronavírus, as marcas das desigualdades socioeconômicas e a aversão à pobreza se potencializaram e se reverberaram no direcionamento excludente das políticas públicas sanitárias, que deixou à margem social, os moradores de rua.
Ações educativas na população infantil em uma unidade de saúde da família no município de Itabuna BA: um relato de experiência
Authors: Monteiro Carolina Peixoto Cavalcanti , Valverde Brenda Bezerra , Sousa Tailla de Morais , Vasconcelos Rayzza Santos , Souza Leonardo Oliveira de , Silva Mônica Bomfim
Published: March 2024

A educação em saúde configura-se como uma potente ferramenta da prevenção e promoção à saúde, que demanda ações intersetoriais e multidisciplinares para atuar sobre os determinantes sociais da saúde. O objetivo é descrever a experiência das ações educativas desenvolvidas durante a disciplina de Integração Extensão Serviço e Comunidade II (IESC II). Trata-se
de um relato de experiência de uma ação educativa realizada no Centro Educacional Gil Nunes Maia no município de Itabuna-Bahia em maio de 2022. Participaram desta ação os discentes de medicina do segundo período; docente do curso de medicina; funcionários da escola; e profissionais de saúde. Compareceram ao evento 74 crianças na faixa etária de 2 a 10 anos e 31 pais ou responsáveis. As crianças participaram efetivamente de todas as atividades propostas, demonstrando interesse e disposição para aprender. No 265 entanto, foi um desafio manter a atenção das crianças, haja vista que nessa faixa etária há uma grande probabilidade de dispersão da concentração, além da inexperiência dos discentes na condução das atividades educativas. As atividades lúdicas representam um instrumento de suporte para o desenvolvimento durante o período da infância, na qual auxilia à expressão de sentimentos pela criança, traz leveza e alegria ao ambiente, favorece a assimilação da linguagem visual e oral. Conclui-se que a intervenção realizada foi de grande relevância para as crianças da comunidade, pois a partir da educação em saúde articulou-se a ludicidade com conteúdo técnico sobre a forma correta de higienização das mãos e higiene bucal.
Atlas Geoambiental de Nova Esperança do Sul-RS
Authors: Ben Franciele Delevati , Schnorr Giorge Gabriel , Robaina Luís Eduardo de Souza , Petsch Carina , Trentin Romario , Sccoti Anderson Augusto Volpato
Published: March 2024

O Laboratório de Geologia Ambiental (LAGEOLAM) da Universidade Federal de Santa Maria (UFSM) vem desenvolvendo uma série "Atlas Geoambiental dos municípios do meio oeste do estado do Rio Grande do Sul" estabelecendo um trabalho de extensão a partir das parcerias com prefeituras e escolas municipais, que poderão usufruir do material construído tanto para fins de planejamento, como para a educação básica. A construção do Atlas Geoambiental municipal de Nova Esperança do Sul é resultado do trabalho coletivo dos acadêmicos do Curso de Geografia Licenciatura da UFSM, Franciele Delevati Ben e Giorge Gabriel Schnorr e também dos professores Luís Eduardo de Souza Robaina, Carina Petsch, Romário Trentin e Anderson Augusto Volpato Sccoti integrantes do grupo de Pesquisa LAGEOLAM do Departamento de Geociências da Universidade Federal de Santa Maria. Este projeto também conta com o apoio financeiro da FAPERGS, UFSM/FIEX e CNPq. Os trabalhos de Zoneamento Geoambientais consistem na análise unificada do espaço geográfico, através de conceitos e métodos que procuram integrar sociedade e natureza que se desenvolve por meio da abordagem sistêmica da paisagem. O Atlas desenvolvido apresenta uma abordagem típica da cartografia geoambiental, que por meio de mapas temáticos, fotografias, tabelas e gráficos, sintetiza informações sobre o município como dados socioeconômicos, histórico, localização, hidrografia local, relevo, geologia, solos, clima, entre outros. A partir dessa compilação de informações, tem-se um material que sintetiza e correlaciona atributos de determinada área. O Atlas busca proporcionar a difusão dos conhecimentos sobre a perspectiva da análise do lugar em que vivemos e suas inúmeras relações que podem ser estabelecidas entre a interface homem e natureza. Dessa forma, o Atlas se mostra um instrumento didático uma vez que informações sobrepostas, analisadas e relacionadas entre si, permitem melhor entendimento do lugar.
Primeiros Religiosos do R. G. do Sul (1736-1848)
Authors: Rubert Arlindo
Published: March 2024

1) Introdução: Diferentemente de muitas outras regiões do país, o Rio Grande do Sul, desde os inícios de sua colonização até meados do século passado, não foi missionado por religiosos nem deles houve residências fixas. Por mais de século e meio, salvo raras exceções que vamos apontar, a Igreja do Rio Grande estêve a cargo do clero secular. Não lhe faltou, porém, a colaboração do clero regular. É o que vamos esboçar no presente trabalho. Assunto inédito, pode-se dizer, visto que nas próprias monografias das Ordens Religiosas pouco ou nada se encontra acêrca de diversos religiosos que exerceram, bem ou mal. seu ministério no território do Rio Grande do Sul, durante esse período...
Blue Laser Conduction Welding of Dissimilar Cu and Al Sheets
Authors:   American Welding Society, TANG ZIJUE , YANG HUIHUI , WAN LE , REN PENGYUAN , ZHANG, XIAOLIN , WU YI , WANG HAOWEI , WANG HONGZE
Published: March 2024

Joining Cu-Al with 0.6 mm is important for the high-power density battery in the new energy field. Low laser absorptivity is a challenge in Cu-Al welding with conventional infrared laser at around 1000 nm wavelength, where keyhole welding is necessary. It is difficult to control welding qualities in keyhole welding due to the intense flow and violently changing absorption rate. At 450 nm wavelength, Cu and Al have high laser absorptizzvity which has the potential to implement stable conduction welding. Therefore, this work adopted a blue laser welding system, and for the first time, realized the conduction welding of 0.6 mm Cu and 0.6 mm Al sheets. The welding process, surface appearance, mechanical properties, and electrical properties were investigated. The results showed that high-power (1950 W) could effectively realize stable Cu-Al conduction welding without spatters, and the welding speed could reach 40 mm/s. Compared with an infrared laser, the blue laser could weld Cu-Al using the form of Cu on top and Al on bottom, which was beneficial for a wide process window and stable welding process. A larger bead width and more consistent intermetallic compound thickness resulting from the blue laser were conducive to performance improvement. In addition, the relationship between welding parameters, molten pool characteristics, and process qualities was built. It provided a possibility to control the welding quality under the influence of strong heat accumulation and high thermal conductivity. This work demonstrated that blue laser has great potential in joining Cu-Al for new energy applications.
Aeroponics vertical indoor farming
Authors: B Mano  , B Arthi  , M Arthi  , R Asha  , P Dhivya prabha
Published: March 2024

Aeroponics vertical indoor farming is a farming that involves growing crops in layers that are piled vertically. Aeroponics is a method of growing plants without soil. Vertical indoor farming is climate controlled so it can be done year-round regardless of environmental challenges. Emerging problems of food security, urbanization, farmland shortage, food miles increased greenhouse gas emissions focus on the need for vertical farming physiological constraints that occur within hydroponic systems. Today, agriculture especially in India to concentrate in some situation such as how to increase the productivity and profit. This paper presents a methodology for developing the plants are submerged in a nutrient-rich mist solution. This study challenges is cultivating the plant by organic farming natural nutrition.
Wheel-rail impact load due to the loss of sleeper-ballast interface
Authors: Mahsa Farshidi  , Yazdan Mohammadian Haft-cheshmeh  , Jafar Hosseini Manoujan
Published: March 2024

This paper presents a comprehensive study on the simulation and analysis of the loss of sleeper-ballast interfaces in railway systems. Through a combination of Multibody Dynamics (MBD) and Finite Element Analysis (FEA) techniques, accurate modeling and validation processes were employed to investigate the impact of interface loss on wheel-rail impact load. Various scenarios were explored, revealing significant findings: for fewer than 4 sleeper-ballast interface losses, a notable 30% increase in wheel-rail impact load was observed, while the rate of increase in wheel-rail impact load diminished for more than 4 sleepers. Furthermore, gap size emerged as a critical factor, with sizes between 0.2 mm and 1.6 mm leading to a load increase exceeding 65%. The study also highlighted the substantial influence of train speed on load dynamics, particularly evident at speeds up to 200 km/h, where loads escalated significantly, resulting in a 180% increase under adverse conditions. These findings emphasize the importance of considering various factors in maintaining railway infrastructure integrity and safety.
Pariwisata Keagamaan di Indonesia: Tinjauan Literatur Sistematis dan Analisis Bibliometrik
Authors: Winoto Yunus , Anwar Rully Khaerul , Septian Falih Ijlal
Published: March 2024

This study was conducted to analyze scientific trends on religious tourism in Indonesia through a systematic literature review and bibliometric analysis using the VOSviewer. Based on the data search results using the keywords "religious tourism" and "Indonesia" for publications from 2018 to 2022, after data filtering, a total of 566 articles were obtained. The data search results for the last five years show that publications in the field of religious tourism in Indonesia increased from 2018 to 2020, but there was a decline since then. The development of publications in the field of religious tourism in Indonesia from 2018 to 2020 saw an increase, but since 2021, coinciding with the COVID-19 pandemic, there was a decrease in publications. From the network visualization results, it was revealed that each cluster contains dominant topics linked to several items in other clusters. Meanwhile, the overlay visualization results showed that topics about "tomb" and "historical tourism" are new research topics, while "tourism object" and "natural tourism" are topics that have been researched for a long time. The density visualization results also revealed that topics such as sharia tourism, historical tourism, and religious tourism village are topics with low density and intensity, thus providing opportunities to be explored as research topics.

Keywords: religious tourism, systematic literature review, bibliometrics
Restorative Justice Approach To Certain Criminal Actions With The Threat Of Under Five Years Prison In Functioning Criminal Law As Ultimum Remedium
Authors: Putri Windy Rizky , Effendi Erdianto , Jayakusuma Zulfikar
Published: March 2024

The purpose of this research is to find out the concept of criminal law renewal to place restorative justice as ultimum remedium in certain crimes with a prison sentence of under five years. This type of normative legal research with the type of legal synchronization. Collecting data on normative legal research uses data collection techniques from a literature study. In drawing conclusions the author uses the deductive thinking method, namely a way of thinking that draws conclusions from a general statement or argument into a specific statement. the results of research and discussion can be concluded. First; The restorative justice approach to criminal acts with the threat of imprisonment for under five years finds its footing in the basic philosophy of Pancasila, namely in accordance with the 4th precept of Pancasila "Deliberation to reach consensus". Currently, restorative justice has been regulated in various regulations/policies. The contents of this internal policy show that there is no uniformity in understanding and boundaries of criminal acts that can be resolved through restorative justice and does not create an Integrated Criminal Justice System. and the imposition of criminal sanctions on perpetrators
Post-Jubilee Reports of the Club of Rome: In Search of a Conceptual Strategy for Humanity’s Foreseeable Future
Authors: Los Viktor A.
Published: March 2024

The article analyzes the reports of the Club of Rome issued subsequent to its semicentennial celebration. The analysis uncovers the evolutionary trajectory of the Club’s conceptual frameworks, transitioning from the stark alarmism prevalent in the early 1970s to a grounded optimism characteristic of the early 21st century. The majority of its publications, in explicit or implicit form, essentially respond to a question of Hamletian scale that arose within the discussions of the “limits to growth” model: Is it possible, and if so, how, to overcome the antagonism between the continuous growth of the needs of an increasing humanity and the relatively limited natural-resource potential of the biosphere? The analysis introduces an analysis of world development scenarios by 2050, ranging from inertial extrapolation of current trends to radical transformations of global political, socio-economic, and cultural processes. The discourse reflects on the report authors’ contemplations regarding societal adaptability to undergo a “true human revolution,” entailing a fundamental reassessment of established economic models and advancement toward innovative global governance strategies. The paper scrutinizes the assertion that society’s “unlearnability” is one of the key obstacles to the sustainable development of civilization. Significant emphasis is placed on the imperative for a comprehensive transformation encompassing the global educational landscape and the cultivation of a novel (sustainable) mindset, one that appreciates the intricate interplay among economic, environmental, and sociocultural perspectives on the global dynamics of the “humanity – biosphere – civilization” system. Humanity, overcoming the turbulences of contemporary world development, possesses all the prerequisites for a constructive analysis and design of strategic perspectives of the foreseeable future.
Peningkatan Kemampuan Sains Anak Melalui Metode Eksperimen Balon Ilmiah Pada Anak Di Taman Kanak-kanak Islam Bunayya
Authors: Rosevina Saleh Quinta , Arbayah  , Sjamsir Hasbi
Published: March 2024

The background of research at Bunayya Islamic Kindergarten is that there are still many children in the B1 group whose science skills are still lacking. Children are less motivated to discover new facts, explore and tackle discovered problems. Therefore, through experimental methods, scientific balloons can improve children's science skills in cognitive development. The formulation of the problem in this study is "Whether through the experimental method scientific balloons can improve science skills in group B1 children of Bunayya Islamic Kindergarten "

Research at Bunayya Islamic Kindergarten includes a type of classroom action research using qualitative descriptive analysis techniques by summing, looking for the average value, midpoint and percentage so that the flow of thinking has been read through a table that describes the results of the assessment achieved by children. The object of research was 17 children in group B1 of Bunayya Islamic Kindergarten.

Based on the results of research in the first cycle, the average number of grade grades of 838 and 49 was categorized as Starting to Develop with the percentage of children who obtained Developing as Expected scores of around 47% and Starting to Develop scores of around 53%. In cycle II, the average number of grade grades of 1053 and 62 was categorized as Developing as Expected with the percentage of children who obtained Very Good Development scores of around 12% and Developing as Expected scores of around 88%. From these results, it can be concluded that the scientific balloon experimental method improves science skills in group B1 children of Bunayya Samarinda Islamic Kindergarten.
PENGARUH DUKUNGAN TEMAN SEBAYA TERHADAP POLA PIKIR BERWIRAUSAHA PADA PELAKU USAHA MUDA DI KOTA BONTANG
Authors: Irianto  , Sa'ad Muhammad Ibnu
Published: March 2024

Youth entrepreneurship has a signiﬁcant impact on productivity, economic growth and the creation of new technologies. Peer support, entrepreneurship education, and self-eﬃcacy have been shown to inﬂuence students' entrepreneurial intentions.Social support from family and peer environment is also related to entrepreneurial intention. In addition, research also shows thatpeers have a signiﬁcant inﬂuence on entrepreneurial career choice, even greater than the inﬂuence of parents. Therefore, it can be concluded that peer support plays a signiﬁcant role in the development of an entrepreneurial mindset in young entrepreneurs. Thisshows the importance of paying attention to social environmental factors, such as peer support, in an eﬀort to develop anentrepreneurial spirit in the younger generation.
Improving Fine Motor Skills Through Weaving Activities in Children Aged 5-6 Years at Keledang Loa Janan Ilir Samarinda Kindergarten
Authors: Tri Mukti Novita , Liana Heppy , Aslina Yeni
Published: March 2024

School as a formal educational institution carries out a series of planned and organized activities, including activities in the teaching and learning process in classrooms at school, directing students to gain understanding, skills, attitudes and values, all of which support student development. The success or failure of achieving educational goals depends a lot on the teaching and learning process that occurs at the learning process point in the classroom, the main factor being the students. The type of research used in this research is classroom action research (PTK). Which aims to improve fine motor skills through weaving activities. The research subjects consisted of class B4, totaling 16 students, consisting of 8 girls and 8 boys at Keledang Loa Janan Ilir Samarinda Kindergarten. The research object was to improve fine motor skills through weaving activities in Keledang Kindergarten students. The percentage is used to describe the increase in student learning outcomes from cycle I and cycle II using the formula according to Daryanto (2011: 192) namely Students who complete their studies in (times) x 100% in (divide): total number of students. in the weaving activities of students in cycle I, meeting I obtained Developing Values ​​According to Expectations (BSH) as many as 3 students and meeting II obtained Developing Values ​​According to Expectations (BSH) as many as 7 students and meeting III was still the same as meeting II with Developing Values ​​According to Expectations (BSH) as many as 7 Students. In cycle II, meeting I obtained Developing Values ​​According to Expectations (BSH) of 8 students and meeting II obtained Developing Values ​​According to Expectations (BSH) of 11 students and meeting III obtained Developing Values ​​According to Expectations (BSH) of 14 students. The graph of the increase in student weaving activities at the Keledang Loa Janan Ilir Samarinda Kindergarten from February and March from cycle I to Cycle II. Weaving activities using origami paper in the B4 group of Keledang Loa Janan Ilir Samarinda Kindergarten have increased. From the results of observations of students' weaving activities, it can be seen that there was an increase in students in each action cycle, in cycle I with a Developing Value According to Expectations (BSH) and a percentage of 43.57% in the sufficient category, and in cycle II with a Developing Value According to Expectations (BSH) and a percentage of 87.5% in the good category
Эффективность стимуляторов роста при возделывании лука в Волго-Донском междуречье
Authors: Павленко В. Н. , Зайцев В. А.
Published: March 2024

С 2018 по 2022 г. на опытном поле Волгоградской области в Волго-Донском междуречье на светло-каштановых почвах закладывали двухфакторные опыты со стимуляторами роста при возделывании гибридов лука репчатого. Изучали влияние стимуляторов роста Циркон и Биостим на продолжительность вегетационного периода гибридов лука Саманта F1, Манас F1 и Сабросо F1, биометрические показатели, урожайность и экономическую эффективность. Установлено, что наиболее оптимальные биометрические показатели и максимальные результаты продуктивности посевов и экономической эффективности формировались у гибрида Сабросо F1 при применении стимулятора роста Биостим: число растений — 885 тыс./га; длина наибольшего листа — 49,6 см; количество листьев на 1 растении — 13; товарная урожайность — 103,3 т/га; прибыль — 278 тыс. руб./га; рентабельность — 37 %.
Энергетическая эффективность зерновых культур на склоновом ландшафте
Authors: Воронов Сергей Иванович , Плескачёв Юрий Николаевич , Астарханова Тамара Саржановна , Нахаев Магомед Рамзанович
Published: March 2024

В лесостепной зоне Чеченской Республики в период 2017 – 2021 гг. оптимизированы приёмы основной обработки почвы и проведена биоэнергетическая оценка возделывания зерновых культур (озимая и яровая пшеницы, горох, яровой ячмень) на склоновом ландшафте. Содержание энергии в урожае у озимой пшеницы сорта Капитан на делянках с углублением увеличивалось на 5428 МДж/га в сравнении с делянками, на которых проводили вспашку, и на 13324 МДж/га в сравнении с делянками с мелкой дисковой обработкой. Коэффициент энергетической эффективности в варианте применения отвальной вспашки у яровой пшеницы сорта Курьер по сравнению с вариантом мелкой дисковой обработки был 0,31 ед. больше. Максимальный коэффициент энергетической эффективности гороха сорта Борец оказался в варианте отвальной обработки с углублением — 3,63 ед.; у ярового ячменя — в варианте отвальной обработки с углублением — 4,27 ед.
Expression and Regulatory Ability of Long Non-Coding RNADLX6 Antisense RNA 1 in Gestational Diabetes Mellitus
Authors: Huang Qiuhong , Tang Lichun , Meng Xiaohui , Wen Meiling , Qin Yin , Liu Jingjing , Luo Xuanxuan , Liang Rong , Dai Xia
Published: March 2024

Background: Gestational diabetes mellitus (GDM) is characterized by elevated blood glucose during pregnancy, which may affect both the fetus and the pregnant woman. This study introduced the expression and regulatory ability of long non-coding RNA (lncRNA) DLX6 Antisense RNA 1 (DLX6-AS1) in patients with GDM, aiming to reveal the action potential and diagnostic value of DLX6-AS1. Methods: This study included 70 pregnant patients with GDM and 50 healthy pregnant women. DLX6-AS1 levels were determined using real-time quantitative polymerase chain reaction (RT-qPCR), and the diagnostic value of DLX6-AS1 was evaluated by receiver operating characteristic (ROC) curve. The GDM cell model was constructed using human chorionic trophoblast cells, and the cell proliferation capacity was assessed using cell counting kit-8 (CCK-8) method. Cell apoptosis was analyzed by flow cytometry. Moreover, luciferase assay was performed to evaluate the relationship between DLX6-AS1 and miR-497-5p. Results: DLX6-AS1 and blood glucose levels were markedly increased in GDM patients, and a positive correlation was observed between both levels (r = 0.7072, p < 0.0001). GDM affected the cell activity, while DLX6-AS1 silencing enhanced the proliferation activity, and suppressed cell apoptosis in GDM cell model via directly targeting miR-497-5p. miR-497-5p expression was low in GDM, and its content was affected by DLX6-AS1 silencing (p < 0.001). Furthermore, DLX6-AS1 exhibited a promising diagnostic function in GDM (area under the curve (AUC) = 0.937, sensitivity = 92.9%, specificity = 86.0%). Conclusions: DLX6-AS1 was positively expressed and mediated GDM through sponge miR-497-5p, suggesting it may be used as a diagnostic factor to predict the occurrence of GDM.
The Effect of Quercetin on Ovary Functions in Rats with Cyclophosphamide Induced Ovary Damage
Authors: Eren Ceren Yildiz , Gurer Hulusi Goktug , Gursoy Ozlem Ozgur , Yilmaz Oktay , Tunc Ece , Aypak Serap Unubol , Asici Gamze Sevri Ekren
Published: March 2024

Background: Premature ovarian failure describes women under 40 who usually present with amenorrhea, hypergonadotropic hypogonadism, and infertility. Quercetin is an antioxidant flavonol. Quercetin’s oxidative, kinase and cell cycle inhibitor activities are known. Our study aimed to examine the efficacy of Quercetin on premature ovarian failure. Methods: Forty-eight regular-cycled adult female Wistar rats weighing 200 ± 40 grams, 10–12 weeks old, were used in the study. They were randomly divided into four groups with 12 animals. Four groups are Control, Cyclophosphamide, Cyclophosphamide + Quercetin (100 mg/kg) and Quercetin (100 mg/kg) groups. At the end of the experiment, the ovarian tissues were quickly removed. Follicles were counted to determine the ovarian reserve. Serum was extracted, and an Anti-Müllerian hormone analysis was performed. RT-PCR (reverse transcriptase–polymerase chain reaction) from ovarian tissue performed mRNA expression analysis of the Ddx4 gene. Results: As a result of Cyclophosphamide administration, it was determined that there was a decrease in both early-stage follicles and total follicles. This decrease was also statistically significant (p < 0.05). Anti-Müllerian hormone levels were significantly lower in the group given Cyclophosphamide (p < 0.01). On the histological examination, the number of early-stage and total follicles was significantly decreased in the Cyclophosphamide group compared to the control group, and those of the Cyclophosphamide + Quercetin were very close to that of the control group. Anti-Müllerian hormone (AMH) levels were also significantly lower in the Cyclophosphamide group compared to the control, but they were recovered to the level of the control group by Quercetin treatment. Conclusions: Our study may prove that Quercetin can protect ovarian function against Cyclophosphamide-induced ovarian damage.
NOP14 as a Potential Predictor of Adult-Type Diffuse Glioma Prognosis and Immunotherapy, is Related to Cell Migration, Proliferation, and CD8+T Cell Infiltration
Authors: Tian Qiu-si , Cheng Jing , Bao Zhi-jun
Published: March 2024

Background: World Health Organization (WHO) grade 4 adult-type diffuse glioma is the most malignant primary tumor of the brain. Nucleolar protein 14 (NOP14) is recognized to contribute significantly to the assembly of small ribosomal subunits. However, the specific involvement of NOP14 in diverse cancers remains poorly understood, particularly its role in adult-type diffuse glioma, which has yet to be elucidated. Methods: A total of 20 adult-type diffuse glioma samples with varying WHO stages were collected. The protein level of NOP14 was detected using immunohistochemistry. Additionally, NOP14 expression in LN229 and U251 cell lines and collected clinical tissue samples was quantified using the Western blot technique. Furthermore, the correlation between NOP14 and clinicopathological features, survival rates, matrix and immune scores, and immune components was investigated using data from the Cancer Gene Atlas database. Results: NOP14 exhibited high expression in adult-type diffuse glioma patients, with the highest expression observed in the LN229 cell line. Moreover, elevated NOP14 expression was significantly correlated with poorer overall survival and demonstrated an association with unfavorable pathological features in a cohort of 703 glioblastoma (GBM) patients. Evidence of a connection between NOP14 and the tumor microenvironment was presented. Elevated NOP14 was linked to the infiltration of CD8+T cell and factors related to epithelial-mesenchymal transition. In in vitro assay, NOP14 was capable of suppressing adult-type diffuse glioma cell invasion and metastasis. Conclusions: NOP14 holds great promise as a candidate biomarker for detecting prognostic, molecular, and immune signatures of adult-type diffuse glioma.
Cisplatin Disrupts Proteasome Bounce-Back Effect through Suppressing ZEB1/Nfe2l1 in Cholangiocarcinoma
Authors: Xiang Yuancai , Jia Man , Gao Yuan , Yang Fang , Wang Teng , Dai Rongyang , Wang Meng , Miao Hongming
Published: March 2024

Background: Bortezomib (BTZ) is a powerful proteasome inhibitor that has been approved for the treatment of haematologic malignancies. Its effectiveness has been assessed against different types of solid tumours. BTZ is ineffective in most solid tumours because of drug resistance, including cholangiocarcinoma, which is associated with a proteasome bounce-back effect. However, the mechanism through which proteasome inhibitors induce the proteasome bounce-back effect remains largely unknown. Methods: Cholangiocarcinoma cells were treated with BTZ, cisplatin, or a combination of both. The mRNA levels of Nfe2l1 and proteasome subunit genes (PSMA1, PSMB7, PSMD1, PSMD11, PSMD14, and PSME4) were determined using quantitative real time polymerase chain reaction (qPCR). The protein levels of nuclear factor-erythroid 2-related factor 1 (Nfe2l1) and proteasome enzyme activity were evaluated using western blotting and proteasome activity assays, respectively. Transcriptome sequencing was performed to screen for potential transcription factors that regulate Nfe2l1 expression. The effect of zinc finger E-box-binding homeobox 1 (ZEB1) on the expression of Nfe2l1 and proteasome subunit genes, as well as proteasome enzyme activity, was evaluated after the knockdown of ZEB1 expression with siRNA before treatment with BTZ. The transcriptional activity of ZEB1 on the Nfe2l1 promoter was detected using dual-luciferase reporter gene and chromatin immunoprecipitation assays. Cell viability was measured using the cell counting kit-8 (CCK-8) assay and cell apoptosis was assessed using western blotting and flow cytometry. Results: Cisplatin treatment of BTZ-treated human cholangiocarcinoma cell line (RBE) suppressed proteasome subunit gene expression (proteasome bounce-back) and proteasomal enzyme activity. This effect was achieved by reducing the levels of Nfe2l1 mRNA and protein. Our study utilised transcriptome sequencing to identify ZEB1 as an upstream transcription factor of Nfe2l1, which was confirmed using dual-luciferase reporter gene and chromatin immunoprecipitation assays. Notably, ZEB1 knockdown using siRNA (si-ZEB1) hindered the expression of proteasome subunit genes under both basal and BTZ-induced conditions, leading to the inhibition of proteasomal enzyme activity. Furthermore, the combination treatment with BTZ, cisplatin, and si-ZEB1 significantly reduced the viability of RBE cells. Conclusions: Our study uncovered a novel mechanism through which cisplatin disrupts the BTZ-induced proteasome bounce-back effect by suppressing the ZEB1/Nfe2l1 axis in cholangiocarcinoma. This finding provides a theoretical basis for developing proteasome inhibitor-based strategies for the clinical treatment of cholangiocarcinoma and other tumours.
Impact of Classical Risk Factors on Subclinical Carotid Atherosclerosis Progression: Insights from a Non-Diabetic Cohort
Authors: Szabóová Eva , Lisovszki Alexandra , Kolarčik Peter , Fatĺová Eliška , Molnár Tomáš , Bujdoš Martin , Szabó Peter
Published: March 2024

Background: Several markers have been proposed for the detection and progression of subclinical atherosclerosis. We aimed to analyse the impact of classical risk factors on the presence and short-term progression of subclinical carotid atherosclerosis in a non-diabetic, primary prevention cohort. Methods: This analysis included participants with completed visits at baseline and at 5-year follow-up (N = 141; 56.7% females, 43.3% males; aged 49.6 ± 4.7 years). Clinical and laboratory parameters, risk profiles, carotid artery intima-media thickness (CIMT) and plaque presence were analysed. Results: There was a significant progression in mean CIMT (0.54 ± 0.09 mm–0.62 ± 0.10 mm; p < 0.001), prevalence of carotid plaque (4.8%–17.9%; p < 0.001) and age- and sex-adjusted abnormal CIMT (52.9%–78.8%; p < 0.001) at the end of follow-up, compared to baseline. In multivariate regression analysis, among the classical risk factors, their number, metabolic syndrome and SCORE (Systematic Coronary Risk Estimation) risk only the number of risk factors showed an independent and significant impact on the occurrence of a carotid plaque (Exp(B) = 1.71; p = 0.017) and 5-year CIMT progression. Conclusions: During a short follow-up, the significant progression of subclinical atherosclerosis was confirmed. The number of risk factors predicted the occurrence of carotid plaques and CIMT progression. The high prevalence and short-term progression of subclinical carotid atherosclerosis underly the rationale for its screening in personalized cardiovascular risk stratification in asymptomatic middle-aged subjects over 50 years old, at low-to moderate cardiovascular risk, particularly with several risk factors.
The Role of Microvascular Obstruction and Intra-Myocardial Hemorrhage in Reperfusion Cardiac Injury. Analysis of Clinical Data
Authors: Ryabov Vyacheslav V. , Vyshlov Evgenii V. , Maslov Leonid N. , Naryzhnaya Natalia V. , Mukhomedzyanov Alexandr V. , Boshchenko Alla A. , Derkachev Ivan A. , Kurbatov Boris K. , Krylatov Andrey V. , Gombozhapova Aleksandra E. , Dil Stanislav V. , Samoylova Julia O. , Fu Feng , Pei Jian-Ming , Sufianova Galina Z. , Diez Emiliano R.
Published: March 2024

Microvascular obstruction (MVO) of coronary arteries promotes an increase in mortality and major adverse cardiac events in patients with acute myocardial infarction (AMI) and percutaneous coronary intervention (PCI). Intramyocardial hemorrhage (IMH) is observed in 41–50% of patients with ST-segment elevation myocardial infarction and PCI. The occurrence of IMH is accompanied by inflammation. There is evidence that microthrombi are not involved in the development of MVO. The appearance of MVO is associated with infarct size, the duration of ischemia of the heart, and myocardial edema. However, there is no conclusive evidence that myocardial edema plays an important role in the development of MVO. There is evidence that platelets, inflammation, Ca2+overload, neuropeptide Y, and endothelin-1 could be involved in the pathogenesis of MVO. The role of endothelial cell damage in MVO formation remains unclear in patients with AMI and PCI. It is unclear whether nitric oxide production is reduced in patients with MVO. Only indirect evidence on the involvement of inflammation in the development of MVO has been obtained. The role of reactive oxygen species (ROS) in the pathogenesis of MVO is not studied. The role of necroptosis and pyroptosis in the pathogenesis of MVO in patients with AMI and PCI is also not studied. The significance of the balance of thromboxane A2, vasopressin, angiotensin II, and prostacyclin in the formation of MVO is currently unknown. Conclusive evidence regarding the role of coronary artery spasm in the development of MVhasn’t been established. Correlation analysis of the neuropeptide Y, endothelin-1 levels and the MVO size in patients with AMI and PCI has not previously been performed. It is unclear whether epinephrine aggravates reperfusion necrosis of cardiomyocytes. Dual antiplatelet therapy improves the efficacy of PCI in prevention of MVO. It is unknown whether epinephrine or L-type Ca2+ channel blockers result in the long-term improvement of coronary blood flow in patients with MVO.
ScholarOne - Exploring the Link between Smartphone Social Media Use and Performance, Focus of Young Table Tennis Players
Authors: Rojas-Valverde Sol , Gomez-Carmona Carlos , Vasquez Aldo , Sanchez-Ureña Braulio , Cabrera Jorge Salas , Rojas-Valverde Daniel
Published: March 2024

This study aimed to explore the immediate effects of smartphone-based
social media use on table tennis performance variables such as reaction
speed, stroke execution accuracy, and focus. A total of 14 young
athletes, consisting of 7 males and 7 females (10.86 ± 1.83 years; 2.43
± 0.65 years of experience in table tennis) participated in a randomized
and counterbalanced quasi-experimental study divided into two groups:
(a) social media group (SMG) and (b) table-tennis videos group (TTVG).
The study assessed four variables: Stroop Test, reaction speed, a
specific table tennis test, and focus (Toulouse-Piéron Test). The
results indicated significant pre- and post-differences in hits, errors,
and total points for both groups (p< .01), with no significant
differences between groups in the three field tests. In conclusion, a
30-minute exposure to either game-related videos or social media stimuli
in children led to improved scores, hits, and errors in the Stroop Test.
These results suggest that acute exposure to virtual stimuli, regardless
of type, enhances inhibitory control and attention abilities
ScholarOne - Association between Depression and Anxiety in Young Adults: The Moderating Role of Meaning in Life
Authors: SANLI Mehmet , ÇİÇEK İLHAN , Kocatürk Metin
Published: March 2024

Mental health problems, including depression and anxiety, are increasing
among young individuals and have become a public health concern. In this
perspective, the search for meaning and purpose is an innate impulse
that contributes to an individual’s psychological well-being. As such,
it plays a crucial role in mental health. Avoiding subjective
evaluations, this statement emphasizes the importance of the search for
meaning in life. In this study, we examined how the relationship between
anxiety and depression is moderated by meaning in life. A total of 2338
participants, 1546 women and 792 men, with an average age of 24.41 were
included in the study. The study examined the moderating effects of
gender, mean age, and meaning in life on the relationship between
anxiety and depression in participants. The data collected from the
study was evaluated for the moderator effect and subjected to regression
analysis. According to the results, meaning in life has a negative
effect on both anxiety and depression as well as a moderator role
between anxiety and depression. In addition, gender has a moderating
role in the relationship between anxiety and depression. In summary,
meaning in life has a protective role against psychological disorders
(anxiety and depression), and high meaning in life protects individuals
against other psychological disorders.