bluuebunny/crossref_metadata_2025 huggingface dataset:
Meiosis initiation: a story of two sexes in all creatures great and small
Authors: Sou Ieng Fong , Pryce Rebecca M. , Tee Wee-Wei , McClurg Urszula Lucja
Published: October 2021

Meiosis facilitates diversity across individuals and serves as a major driver of evolution. However, understanding how meiosis begins is complicated by fundamental differences that exist between sexes and species. Fundamental meiotic research is further hampered by a current lack of human meiotic cells lines. Consequently, much of what we know relies on data from model organisms. However, contextualising findings from yeast, worms, flies and mice can be challenging, due to marked differences in both nomenclature and the relative timing of meiosis. In this review, we set out to combine current knowledge of signalling and transcriptional pathways that control meiosis initiation across the sexes in a variety of organisms. Furthermore, we highlight the emerging links between meiosis initiation and oncogenesis, which might explain the frequent re-expression of normally silent meiotic genes in a variety of human cancers.
LARP6 proteins in plants
Authors: Bousquet-Antonelli Cécile
Published: October 2021

RNA binding proteins, through control of mRNA fate and expression, are key players of organism development. The LARP family of RBPs sharing the La motif, are largely present in eukaryotes. They classify into five subfamilies which members acquired specific additional domains, including the RRM1 moiety which teams up with the La motif to form a versatile RNA binding unit. The LARP6 subfamily has had a peculiar history during plant evolution. While containing a single LARP6 in algae and non-vascular plants, they expanded and neofunctionalized into three subclusters in vascular plants. Studies from Arabidopsis thaliana, support that they acquired specific RNA binding properties and physiological roles. In particular LARP6C participates, through spatiotemporal control of translation, to male fertilization, a role seemingly conserved in maize. Interestingly, human LARP6 also acts in translation control and mRNA transport and similarly to LARP6C which is required for pollen tube guided elongation, is necessary to cell migration, through protrusion extension. This opens the possibility that some cellular and molecular functions of LARP6 were retained across eukaryote evolution. With their peculiar evolutionary history, plants provide a unique opportunity to uncover how La-module RNA binding properties evolved and identify species specific and basal roles of the LARP6 function. Deciphering of how LARP6, in particular LARP6C, acts at the molecular level, will foster novel knowledge on translation regulation and dynamics in changing cellular contexts. Considering the seemingly conserved function of LARP6C in male reproduction, it should fuel studies aimed at deriving crop species with improved seed yields.
Chemical biology approaches to study histone interactors
Authors: Burton Antony J. , Hamza Ghaith M. , Zhang Andrew X. , Muir Tom W.
Published: October 2021

Protein–protein interactions (PPIs) in the nucleus play key roles in transcriptional regulation and ensure genomic stability. Critical to this are histone-mediated PPI networks, which are further fine-tuned through dynamic post-translational modification. Perturbation to these networks leads to genomic instability and disease, presenting epigenetic proteins as key therapeutic targets. This mini-review will describe progress in mapping the combinatorial histone PTM landscape, and recent chemical biology approaches to map histone interactors. Recent advances in mapping direct interactors of histone PTMs as well as local chromatin interactomes will be highlighted, with a focus on mass-spectrometry based workflows that continue to illuminate histone-mediated PPIs in unprecedented detail.
The immune niche of the liver
Authors: Cheng Michael L. , Nakib Diana , Perciani Catia T. , MacParland Sonya A.
Published: October 2021

The liver is an essential organ that is critical for the removal of toxins, the production of proteins, and the maintenance of metabolic homeostasis. Behind each liver functional unit, termed lobules, hides a heterogeneous, complex, and well-orchestrated system. Despite parenchymal cells being most commonly associated with the liver’s primary functionality, it has become clear that it is the immune niche of the liver that plays a central role in maintaining both local and systemic homeostasis by propagating hepatic inflammation and orchestrating its resolution. As such, the immunological processes that are at play in healthy and diseased livers are being investigated thoroughly in order to understand the underpinnings of inflammation and the potential avenues for restoring homeostasis. This review highlights recent advances in our understanding of the immune niche of the liver and provides perspectives for how the implementation of new transcriptomic, multimodal, and spatial technologies can uncover the heterogeneity, plasticity, and location of hepatic immune populations. Findings from these technologies will further our understanding of liver biology and create a new framework for the identification of therapeutic targets.
Explicit and Implicit Cognitive Processes Associated With Microaggression Endorsement
Authors: McLean Mitchell , Roche Jennifer M. , Audet Lisa , Stribling Desiree , Kaufman Rachael
Published: October 2021

Purpose:

Social standards that support White normativity impact communication styles and use of microaggressions that alienate minority and culturally/linguistically diverse groups. Though professionals in education and communication sciences and disorders (CSD) attempt to help students/clients navigate the world, CSD professionals focus more on nonnormativity as different, not bad, whereas mainstream education focuses on meeting normative standards—potentially impacting how preprofessional students approach and understand non-inclusive language. The purpose of this study was to gain an understanding of the prevalence of microaggression endorsement (i.e., indicating they would use a phrase, even if unaware of its potential harm) and adaptation to feedback that may promote changes in microaggressive language endorsements by preservice students in predominantly White-dominated disciplines with different approaches to nonnormativity.

Method:

Computer mouse-tracking was used to explore explicit and implicit cognition before and after corrective feedback regarding the perception and social impact of microaggressions among 37 undergraduate preservice CSD and education majors.

Results:

Preservice CSD undergraduates were far less likely to endorse microaggression statements, and agree with the potential harm microaggressions cause. Preservice CSD undergraduates also experienced more cognitive competition when making decisions about microaggressions, but this cognitive competition lessened after feedback.

Conclusions:

This study of microaggressions is promising, as it demonstrates that preservice educators and CSD undergraduates are sensitive to the harm microaggressions cause, but both groups of preprofessionals may still hold some non-inclusive notions that may be damaging to colleagues, clients, and students. Fortunately, this understanding of the research suggests that awareness may be an important factor affecting change, promoting cultural competence, and providing opportunities for reflection.

Supplemental Materials:

https://osf.io/kax8t/
Multi‐stream adaptive spatial‐temporal attention graph convolutional network for skeleton‐based action recognition
Authors: Yu Lubin , Tian Lianfang , Du Qiliang , Bhutto Jameel Ahmed
Published: October 2021

Skeleton‐based action recognition algorithms have been widely applied to human action recognition. Graph convolutional networks (GCNs) generalize convolutional neural networks (CNNs) to non‐Euclidean graphs and achieve significant performance in skeleton‐based action recognition. However, existing GCN‐based models have several issues, such as the topology of the graph is defined based on the natural skeleton of the human body, which is fixed during training, and it may not be applied to different layers of the GCN model and diverse datasets. Besides, the higher‐order information of the joint data, for example, skeleton and dynamic information is not fully utilised. This work proposes a novel multi‐stream adaptive spatial‐temporal attention GCN model that overcomes the aforementioned issues. The method designs a learnable topology graph to adaptively adjust the connection relationship and strength, which is updated with training along with other network parameters. Simultaneously, the adaptive connection parameters are utilised to optimise the connection of the natural skeleton graph and the adaptive topology graph. The spatial‐temporal attention module is embedded in each graph convolution layer to ensure that the network focuses on the more critical joints and frames. A multi‐stream framework is built to integrate multiple inputs, which further improves the performance of the network. The final network achieves state‐of‐the‐art performance on both the NTU‐RGBD and Kinetics‐Skeleton action recognition datasets. The simulation results prove that the proposed method reveals better results than existing methods in all perspectives and that shows the superiority of the proposed method.
Parallel GPF solution: A GPU‐CPU‐based vectorization parallelization and sparse technique for NR implementation
Authors: Zhao Jingbo , Tao Yan
Published: October 2021

As an essential simulation tool, global power flow (GPF) can approximately model mutual impacts of interactions between transmission system (TS) and distribution system (DS). However, sequential GPF lacks timely solution performance required in several applications built on top of GPF, for example, contingency analysis. To address this issue, graphic processing unit (GPU) with excellent floating‐point arithmetic operations is introduced and in turn a Master‐Slave‐Splitting (MSS) based parallel GPF approach is proposed via vectorization parallelization under GPU‐CPU heterogeneous architecture. First, the root cause behind sparsity property of GPF and its impacts on key steps of NR‐based GPF approach are quantitatively analysed. Considering the studies carried out in the authors' previous work of the application of GPU and sparse techniques on TS power flow (TS‐PF), its applications on parallel implementations of corresponding steps engaged in three‐phase imbalanced DS power flow (DS‐PF) is mainly focused on. Numerical studies validate the effects of various custom‐designed parallel schemes on acceleration enhancement of individual steps in the proposed GPU‐CPU parallel GPF approach.
Case study of power allocation strategy for a grid‐side lead‐carbon battery energy storage system
Authors: Li Xining , Geng Guangchao , Jiang Quanyuan , Ma Junchao , Ni Qiulong , Guo Kaijie
Published: October 2021

Battery energy storage system (BESS) is an important component of future energy infrastructure with significant renewable energy penetration. Lead‐carbon battery is an evolution of the traditional lead‐acid technology with the advantage of lower life cycle cost and it is regarded as a promising candidate for grid‐side BESS deployment. However, inconsistency among lead‐carbon batteries in a BESS is a major concern which has to be carefully considered in practical operation. One of the available approaches to relieve this issue is to develop a sophisticated power allocation strategy (PAS) among multiple converters inside the BESS. This work conducts a comprehensive case study on the impact of PAS in a grid‐side 12 MW/48 MWh BESS recently constructed in Zhejiang, China (Zhicheng energy storage station, the first grid‐side lead‐carbon BESS in China). Three different PASs (i.e. averaged, state weighted and state prioritized) are investigated and benchmarked with two typical BESS application scenarios of peak shaving and frequency regulation, from real‐world experiments using the aforementioned BESS. The performance of the strategies is quantitatively evaluated by three indices defined in this work. The state prioritized strategy is found to be the most effective for this lead‐carbon BESS.
Overall spectral properties of prompt emissions with diverse segments inSwift/BAT short gamma-ray bursts
Authors: Li X. J. , Zhang Z. B. , Zhang K.
Published: October 2021

Owing to a lack of multiple components of promptγ-ray emissions in short gamma-ray bursts (sGRBs), how these distinct components are correlated remains unclear. In this paper we investigate the spectral and temporal properties of precursors, main peaks, and extended emissions in 26 sGRBs including GRB 170817A. It has been found that peak energies (Ep) in each pulse are uncorrelated with the pulse duration (tdur). Meanwhile, we find that there is no obvious correlation between peak energy and energy fluence. Interestingly, there is no obvious spectral evolution from earlier precursors to later extended emissions in view of the correlations oftdurwith either theEpor the low-energy spectrum index,α. A power-law correlation between the average flux (Fp) and the energy fluence (Sγ), logFp = (0.62 ± 0.07) logSγ + (0.27 ± 0.07), is found to exist in the individual segments instead of mean peaks. Furthermore, we also find that the main peaks are on average brighter than the precursors or the extend emissions by about one order of magnitude. On the basis of all the above analyses, we can conclude that three emissive components could share the same radiation mechanisms, but that they might be dominated by diverse physical processes.
A solar flare driven by thermal conduction observed in mid-infrared
Authors: López Fernando M. , Giménez de Castro Carlos Guillermo , Mandrini Cristina H. , Simões Paulo J. A. , Cristiani Germán D. , Gary Dale E. , Francile Carlos , Démoulin Pascal
Published: October 2021

Context. The mid-infrared (mid-IR) range has been mostly unexplored for the investigation of solar flares. It is only recently that new mid-IR flare observations have begun opening a new window into the response and evolution of the solar chromosphere. These new observations have been mostly performed by the AR30T and BR30T telescopes that are operating in Argentina and Brazil, respectively.

Aims. We present the analysis of SOL2019-05-15T19:24, a GOES class C2.0 solar flare observed at 30 THz (10 μm) by the ground-based telescope AR30T. Our aim is to characterize the evolution of the flaring atmosphere and the energy transport mechanism in the context of mid-IR emission.

Methods. We performed a multi-wavelength analysis of the event by complementing the mid-IR data with diverse ground- and space-based data from the Solar Dynamics Observatory (SDO), the H-α Solar Telescope for Argentina, and the Expanded Owens Valley Solar Array (EOVSA). Our study includes the analysis of the magnetic field evolution of the flaring region and of the development of the flare.

Results. The mid-IR images from AR30T show two bright and compact flare sources that are spatially associated with the flare kernels observed in ultraviolet (UV) by SDO. We confirm that the temporal association between mid-IR and UV fluxes previously reported for strong flares is also observed for this small flare. The EOVSA microwave data revealed flare spectra consistent with thermal free-free emission, which lead us to dismiss the existence of a significant number of non-thermal electrons. We thus consider thermal conduction as the primary mechanism responsible for energy transport. Our estimates for the thermal conduction energy and total radiated energy fall within the same order of magnitude, reinforcing our conclusions.
Reproductive compatibility of Sorbocotoneaster with mountain ash species and varieties that are promising for breeding in Siberia
Authors: Asbaganov Sergey
Published: October 2021

In Russia, in the Republic of Yakutia, there is the only point in the world where natural intergeneric hybridization of species of the genera Sorbus and Cotoneaster is observed, resulting in the formation of a new hybridogenic genus ×Sorbocotoneaster with a rich polymorphism of parental genera traits. For the selection of mountain ash in Siberia, it is promising to involve Sorbocotoneaster genotypes in artificial hybridization as sources of a complex of economically valuable traits, including winter hardiness, short stature, and self-fertility. Artificial hybridization of the tetraploid selective form Sorbocotoneaster with selected forms and varieties of Sorbus sibirica, S. aucuparia, S. sambucifolia and their hybrids allows obtaining viable hybrid offspring in combinations where Sorbocotoneaster is used as a pollen donor.
Taxonomic analysis of Pomir’s bryoflora
Authors: Boborajabov Bobokhon
Published: October 2021

The bryoflora of the Pamirs includes 209 species of bryophytes: 12 marshans, 2 sphagnum and 195 true mosses and 12 varieties, which are representatives of 89 genera, 38 families, 18 orders, 6 classes, 2 divisions - Marshantiophyta and Bryophyta. For the first time, 78 species are given for the bryoflora of the Pamirs, for Tajikistan - 17 species, of which 13 are new for the bryoflora of Central Asia.The leading families in terms of the number of species are Pottiaceae - 57, Bryaceae -36, Amblystegiaceae - 26, Grimmiaceae - 12, Brachytheciaceae - 8, Mniaceae - 6, Dicranaceae, Encalyptaceae 5 species each, Fissidentaceae and Funariaceae 4 species each. The ten leading families contain 163 species, which is 78.0% of the bryoflora of the Pamirs.
Variation of macroand trace elements in organs of the blue honeysuckle subspecies of various environmental and geographic provenance when grown in the Near-Ob foreststeppe (West Siberia, Russia)
Authors: Boyarskikh Irina G. , Siromlya Tatyana I.
Published: October 2021

The variation limits and organ distribution of macroand trace elements were determined in plants of the three subspecies of Lonicera caerulea L. The leaves, as compared with the stems, were found to accumulate more of B, Са, Mg, Mo, P and Sr and less of Al, Mn, Ti and Zn. The plants of different subspecies, grown on soils of the similar chemical element composition, showed statistically significant differences in contents and organ distribution patterns of Al, Cr, Cu, Fe, Mg, Mo, Na, Ni, Pb, Si, Ti and Zn. The stems of the subspecies of the Far East provenance (L. сaerulea subsp. kamtschatica and L. сaerulea subsp. venulosa) had abnormally high contents of Al, Cr, Fe, Na, Si and Ti.
The effect of growing conditions and pollination mode on the Lonicera caerulea berry mass
Authors: Boyarskikh Irina G.
Published: October 2021

The berry mass of the blue honeysuckle plants of different environmental and geographical provenance was shown to be affected by the weather conditions at the time of the fruit setting and ripening. Pollination by defective pollen and by the pollen of closely-related species resulted in the decreased berry mass.
Lianas collection from the Botanical Garden and its science-practice utilization
Authors: Dorofeyeva Ludmila
Published: October 2021

Collection of many years’ lianas gathered in Botanical Garden, placed in south-taiga boreal area of Middle Ural. The collection bank of voluble plants is exposed of 12 genus and 17 families growing wild species of lianas originating from various areas of the Earth temperate zone and contains of more than 200 taxons. The most imposing among them is collection of genus Clematis L., which contains species of natural flora and sorts of Clematis from Russian and World selection of more than 200 taxons. Taxons are listed and analyzed by biomorphic and geographic criteria. Many years observing of collected specimens allowed getting important data about influence of climatological changes on winter hardness and procreational functions Aristolochia manschuriensis, A. macrophylla.
The gene pool of the black apricot - Prunus dasycarpa Pers. and its use in stone fruit crops breeding
Authors: Eremin Gennady , Eremin Viktor , Gasanova Taisiya
Published: October 2021

The article presents the results of research aimed at studying varieties, forms and hybrids of black apricot – Prunus dasycarpa Pers., preserved in the gene pool of the Krymsk EBS, VIR Branch, and identifying the feasibility of including genotypes of this species and hybrid seedlings in breeding programs to create new adaptive varieties with high fruit quality and easy vegetative reproduction of clonal rootstocks of stone fruit crops. It was revealed that cross-species hybridization of black apricot with stone fruit crops, in particular apricot and cherry plum, allows to create adaptive genotypes suitable for cultivation, as well as being a valuable source material for further breeding use. For production use, the varieties of the Krymsk EBS breeding are of interest: black apricot - Kubansky Cherny (45234)*, Cherny Barkhat (45235)*, Kolibri (45240)*, Plemkot Kubansky (26217)*; Russian plum Globus (43854)*; clonal rootstock Alab 1 (18213)* (*VIR catalogue No.).
Taxonomy of Aquilegia glandulosa Fischer ex Link and related species (Ranunculaceae) in North Asia
Authors: Kaigalov I.V. , Erst A.S. , Tashev N. A. , Wang W.
Published: October 2021

The paper presents the annotated checklist and morphological differences of the Aquilegia glandulosa from the nearest related species and provides new data on the distribution of all species from this group. An identification key to the species of Aquilegia glandulosa group from the North Asia is provided and diagnostic characters are discussed.
Analysis of intraspecific polymorphism ofNitraria sibiricaPall. using the ISSR technique
Authors: Khozyaykina Sofia A. , Banaev Evgeny V.
Published: October 2021

The analysis of DNA polymorphism ofNitraria sibirica Pall. was carried out at 13 natural populations of the Republic of Altai and Altai Territory using the ISSR technique. Seven effective ISSR primers have been identified to analyze DNA polymorphism inN. sibirica. 99 DNA fragments were yielded at DNA amplification with these primers, 66 of them were polymorphic. The genetic distance Nei (D) between the studied populations ofN. sibiricaaveraged 0.32, at mean 0.09 - within populations. An identification ISSR marker has been revealed, which can be used to study the genetic variability of the genusNitraria L. (Nitrariaceae)species.
Biologically active and reserve substances of Siberian peonies
Authors: Kostikova Vera A. , Kalendar Olga V. , Tashev Nikolai A. , Erst Andrey S. , Vasilyeva Olga Yu.
Published: October 2021

Levels of biologically active and reserve substances were investigated in the leaves and rhizomes of Paeonia anomala L., P. hybrida Pall., and P. lactiflora Pall. The peonies’ leaves are rich in ascorbic acid (1205.7 mg/100g in P. anomala) and tannins (15.9% in P. lactiflora and 15.7% in P. anomala) at the beginning of the growth season. Concentrations of flavonols, pectins, and carotenoids in the Siberian peonies are low at the beginning of the growth season. P. lactiflora is a promising species for further research on the set and levels of biologically active and reserve substances in rhizomes because this species stands out among the three Siberian species in terms of the levels of catechins (1297.8 mg/100g), protopectins (10.1%), saponins (19.2%), and sugars (22.1%) in rhizomes. In these parts of the plant, starch (18.6%) accumulates the most in P. hybrida among the studied peonies species. Concentrations of the analyzed substances in the rhizomes of the peonies change significantly by the end of the growth season and vary widely among these species. Levels of ascorbic acid (except for P. hybrida), protopectins, and starch increase significantly while concentrations of catechins and sugars decrease in the rhizomes by the end of the growth season.
Diagnostic potential of epiphytic bryophytes in forest vegetation classification
Authors: Kucherov Ilya , Grishutkina Galina , Teleganova Victoria , Potemkin Alexey
Published: October 2021

The article reveals that epiphytic and epixylic bryophytes could be successfully used as differentials in classification of forest communities together with vascular plants and epigeic cryptogams, the fact proved for broadleaved forests in European Russia.
Expression of adaptation potential by cultivars of highbush blueberry when introduced to Belarusian Polesia
Authors: Kurlovich Tatyana V.
Published: October 2021

Highbush blueberry is a group of endemic species from North America. Its introduction to Belarusian Polesia is associated with transfer of cultivars of this group into an environment with a harsher climate. Adaptive capacity of highbush blueberry allowed its cultivars to adapt to the new environment, fully develop their fruits and complete their vegetation cycle. The property of the plants to fully utilize the time of their vegetation period manifested as shortening of the completion of the main phenophases due to the influence of the temperature factor. In an introduced environment the speed of the phenophases significantly depended on the peak day temperatures, which allowed the cultivars to successfully develop their fruits in an environment where they don’t receive sufficient heat during the vegetation period, as well as to complete the vegetation cycle.
The anatomy of rose shoots
Authors: Pashina Marina
Published: October 2021

In may 2021, rose shoot samples of 3 rose species from 2 sections were collected: R. foetida from section Pimpinellfolia (DC.) Ser., R. majalis and R. rugosa from section Cinnamomeae (DC.) Ser. This article reviews anatomical structure of collected samples. The common attributes of rose stems anatomical structure are specified. The structure of vascular tissues is continuous. The differences in anatomy of the studied species are identified.
Structural rearrangements in plastid genomes of Apiaceae as phylogenetic markers
Authors: Samigullin Tahir , Vallejo-Roman Carmen , Degtjareva Galina , Terentieva Elena
Published: October 2021

Apiaceae belong to angiosperm families with frequent plastome structural rearrangements, some of which are generally regarded as synapomorphic for large clades, although typically with limited taxon sampling. Our study aims to improve understanding of the structural rearrangements in plastome within the Tordylieae tribe (ApiaceaeApioideae) with a dense sampling scheme of its species. We showed that presence of psbA pseudogene in inverted repeats near the border with a large single-copy region, which is found in the Tordylieae tribe, may be a clade-specific synapomorphy.
Modification of a cement binder in structural concrete for mine and underground construction
Authors: Uglyanitsa Andrey , Duvarov Vladimir
Published: October 2021

The issues of the modification of a binder in structural cement concrete for mine and underground construction with wastes of chemical enterprises are considered in the article. Hundreds of tons of waste are generated annually at chemical enterprises of the Russian Federation, polluting the environment and requiring their disposal. The performed studies deal with the improvement of physical and mechanical properties of a cement binder with a dispersed manganese sludge modifier, which is a waste product of ammonia or methanol production, for its use in mine and underground construction. As a result of the studies performed, it was found that the addition of dispersed sludge with manganese oxide in an amount of 4% of the cement mass to a cement binder leads to the activation of the cement hydration process, while the rate of development of the plastic strength of the cement stone structure increases, the period of its structure formation reduces and the compressive cement stone strength increases by 17-18%, which makes it possible to reduce the cement content in structural concrete by 8.8-10.0% while maintaining its strength, reducing the cost of mine and underground structures and, as a result, reducing the cost of mining.
Simulation modeling of the power supply system of the coal mine excavation area with facts devices
Authors: Voronin Vyacheslav , Nepsha Fedor , Kulikov Andrew , Korneev Anton , Khasanova Anastasia
Published: October 2021

The introduction of technologies for active-adaptive control of the operating modes of the power supply systems of coal mines can contribute to an increase in the energy efficiency of coal mining. High-response FACTS devices of the second generation can be used for dynamic reactive power compensation, voltage regulation and limitation of current and voltage harmonic components in conditions of sharply variable electrical loads of mining machines at a breakage face. Evaluation of the effectiveness of the implementation of FACTS devices in the power supply systems of coal mines can be performed using simulation methods.This article discusses the main approaches to the development of a simulation model of a power supply system of a coal mine, mining equipment and FACTS devices. The main results of modeling the joint operation of mining machines are shown. Conclusions about the effectiveness of the use of FACTS devices in the extraction area of a coal mine are made.
Chemical monitoring of the socio-ecological situation in resource-producing regions
Authors: Marasova Daniela , Zolotukhin Vladimir , Zolotukhina Natalia , Volkova Olga , Yazevich Mariya
Published: October 2021

The article examines the problems associated with the environmental situation in resource-producing regions, the causes of which are associated with air pollution, soil, water bodies, etc. as a result of human activity, waste from industrial, including coal enterprises. To reduce the negative impact on these processes, as well as to control the ecological state, it is necessary to monitor, including from the chemical point of view, the dynamics of changes in the state of the environment, as well as its impact on a person, his life activity and the surrounding social infrastructure. We are talking about the degree of influence of the level of pollution on human health, on the quality of food consumed and industrial production, which ultimately has a significant impact on the quality of life and demographic processes at the regional level. The necessity of constant chemical monitoring of the composition of the atmospheric air of industrial cities, which is affected by human economic activity, is emphasized. This is especially true for the coal industry, depending on its distance from industrial centers, the state of treatment facilities and socio-economic opportunities for the use and application of "green" technologies. The use of scrubbers ("wet") ash collectors, traditional methods of water treatment, including the use of settling tanks and filter treatment facilities at coal mining enterprises, etc. contribute to the use of cleaning products for the reclamation of land disturbed by coal mines as a result of economic activities. Environmental policy should be implemented in accordance with the regional environmental standard adopted in the Kemerovo Region as part of the development strategy until 2035 and aimed at ensuring environmental-oriented and energy-efficient economic growth.
The concept of technogenic risks of a mining transport complex as a tool of lowering the level of its ecological load
Authors: Zhdanov Vyacheslav , Kosolapov Andrey , Ibragimova Flyura
Published: October 2021

The article considers the basic provisions of the concept of technogenic risks of a mining transport complex in order to solve the problem of lowering the level of its ecological load. The concept of the ecology of operational environment at open-pit works is introduced, as well as, the structure of the technogenic risk function of a mining transport complex is determined to implement the concept. The article emphasizes the necessity of a systematic approach to the solvation of the problem of lowering the level of the ecological load of a mining transport complex, which should take into account all aspects of negative impact on operational environment. The practical methodology of providing the required ecology of mining transport operational environment is provided.
Developing the concept of autonomous control of the quarry vehicles movement
Authors: Chicherin Ivan , Fedosenkov Boris , Dubinkin Dmitriy , Zhenbo Wang
Published: October 2021

Introduction. The article presents the results of studies related to the description of the synthesis and further analysis of the dynamic behavior of unmanned vehicles (UMVs) operating at coal opencast mines and other mining enterprises. The relevance of the research topic is dictated by the need to create safe and effective conditions for overburden / mining and mining transportation operations. This is ensured, among other things, by the operation of unmanned heavy-duty dump trucks. Purpose of the work: in the course of the research, a concept was developed for the formation of route parameters and models of the dynamics of movement of UMVs along technological routes. Methodology. The paper describes the technology for generating and processing signals in control subsystems as part of an automated dispatching system and an on-board subsystem for autonomous control of the UMV. Research methods include the study of the shapes and characteristics of current trajectories (CT) in relation to a nominal axial trajectory (NAT). In this case, a current trajectory of the UMV is considered within the framework of the so-called S-frames, which are formed as geolocations on a certain working UMV route from a bench face to the place of unloading and vice versa. As a variable characterizing the UMV behavior on a current trajectory, a 1D-signal with a time dependent frequency is adopted, the nature of the change of which is determined by the CT dynamic shape relative to the NAT. Results. Such chirp signals – together with the wavelet transforms technique introduced into consideration – allow us in a semantically transparent and information-rich videographic form to display and subject to further processing signals characterizing the current behavior of a UMV on a route. The resulting parameters of such secondary wavelet representations of the current UMV dynamics (wavelet maps) are further planned to be used in the subsystem of dynamic modal control of the UMV movement in the open pit. Conclusions. The results of the studies carried out make it possible to form current routes of UMV movement according to the models generated based on the analytical tools accompanying the dynamics of the UMVs, proposed in the work.
The development of the socio-cultural space of the coal-mining region as a factor of human resources retention
Authors: Kostiuk Natalia , Panina Tatiana , Sambalkhundev Khash-Erdene
Published: October 2021

The article presents an analysis of the problem of human resource retention in the coal-mining region. It is emphasized that along with the factors of economic development it is advisable to take into account the socio-cultural needs and preferences of employees to ensure the preservation of human resources and the development of human capital on this basis. The article substantiates the need to rely on the actual socio-cultural needs of the subjects of professional activity when building activities for the development of the socio-cultural space of the coal-mining region. The article analyzes the implementation of strategic measures for the creation of the Siberian Cluster of Arts from the point of view of the development of the socio-cultural space of the region for the retention of human resources. The empirical part of the article is presented by the results of the study of socio-cultural needs, leisure preferences and the assessment of the attractiveness of the factors of living in Kuzbass by employees of the coal industry enterprises of the region. The sample population included 93 respondents living in the following cities: Kemerovo, Berezovskiy, Kiselevsk, Novokuznetsk, Polysaevo, and Prokopyevsk. The main method of collecting information was a survey conducted through GoogleForms. The analysis uses methods of mathematical statistics, quantitative and qualitative analysis of the results, and analysis of the significance of socio-cultural needs for the respondents.
Analysis for the ARIANE BM1 and BM3 samples: nuclide inventory and decay heat
Authors: Rochman Dimitri , Vasiliev Alexander , Ferroukhi Hakim , Hursin Mathieu
Published: October 2021

The Mixed Oxide samples (MOX) ARIANE Post Irradiation Examination samples BM1 and BM3 have been analyzed in this work, based on various two- and three-dimensional models. Calculated and measured nuclide inventories are compared based on CASMO5, SIMULATE and SNF simulations, and calculated values for the decay heat of the assembly containing the samples are also provided. For uncertainty propagation, the covariance information from three different nuclear data libraries are used. Uncertainties from manufacturing tolerances and operating conditions are also considered. The results from these two samples are compared with the ones from two UO2 samples, namely GU1 and GU3, also from the ARIANE program, applying the same calculation scheme and uncertainty assumptions. It is shown that a two-dimensional assembly model provides better agreement with the measurements than a two-dimensional single pin model, and that the full core three-dimensional model provides similar results compared to the assembly model, although no 148Nd normalization is applied for the full core model. For the MOX assembly decay heat, as expected, heavy actinides have a higher contribution compared to the cases with the UO2 samples; additionally, decay heat uncertainties are moderately smaller in the case of the MOX assembly.
Complexity issues of perfect secure domination in graphs
Authors: Chakradhar P. , Venkata Subba Reddy P.
Published: October 2021

Let G = (V, E) be a simple, undirected and connected graph. A dominating set S is called a secure dominating set if for each u ∈ V \ S, there exists v ∈ S such that (u, v) ∈ E and (S \{v}) ∪{u} is a dominating set of G. If further the vertex v ∈ S is unique, then S is called a perfect secure dominating set (PSDS). The perfect secure domination number γps(G) is the minimum cardinality of a perfect secure dominating set of G. Given a graph G and a positive integer k, the perfect secure domination (PSDOM) problem is to check whether G has a PSDS of size at most k. In this paper, we prove that PSDOM problem is NP-complete for split graphs, star convex bipartite graphs, comb convex bipartite graphs, planar graphs and dually chordal graphs. We propose a linear time algorithm to solve the PSDOM problem in caterpillar trees and also show that this problem is linear time solvable for bounded tree-width graphs and threshold graphs, a subclass of split graphs. Finally, we show that the domination and perfect secure domination problems are not equivalent in computational complexity aspects.
The natural factors and anthropogenic stressors influence on Chironomidae communities of two north-African wadis
Authors: Hamache Ceria , Płóciennik Mateusz , Saal Imane , Arab Abdeslem
Published: October 2021

Mediterranean streams reveal high biodiversity and play a crucial role for local populations. North African wadis are less known than European streams. Hence, there is a need to explore factors influencing their communities. Chironomid assemblages of the Seybouse and El Kebir-west wadis, located in Algeria, were surveyed between July 2016 and July 2017. Among 28,045 collected larvae, 51 taxa were identified. The obtained results indicate that wadis saprobity, conductivity and pH vary seasonally. Air temperature and precipitation affect wadis differently in summer and winter. Two gradients driven by altitude define the river continuum: (1) the bottom substrate, from coarse to fine, and water quality, (2) the variety of meso-habitats from natural to anthropogenic. El Kebir-west, as a natural wadi, has unified communities throughout all its length. Communities of Seybouse vary due to the fact that this larger river is strongly influenced by human activity. Water management in Algeria should focus equally on water quality and natural habitats treatment.
Tranexamic acid and reduction of blood transfusion in lower limb trauma surgery: a randomized controlled study
Authors: Kaur Gurleen , Selhi Harpal Singh , Delmotra Naresh Jyoti , Singh Jaspreet
Published: October 2021

Introduction: Post-operative blood loss in lower limb trauma fractures increases morbidity. Very few studies have evaluated the efficacy of Tranexamic Acid (TXA) in reducing blood loss and the consequent requirement of blood transfusion in the Indian population. Methods: This was a randomized controlled study of 100 patients with lower limb trauma. Fifty patients were given 1 g of TXA before surgery, and 50 patients were not given TXA. The requirement of blood transfusion, fall in Hb, the number of days admitted in the hospital after surgery were recorded, and evidence of deep vein thrombosis (DVT) was monitored. Results: Baseline demographics between the groups were comparable. The required blood transfusion and fall in Hb in patients receiving intra-operative TXA were significantly lower than those not given TXA (p < 0.0001). There was no significant difference in the length of hospital stay between the two groups (p = 0.6). There was no significant difference in the incidence of DVT in both groups. Discussion: TXA helps reduce the morbidity of trauma patients by reducing the requirement for blood transfusion. Its use is safe in lower limb trauma surgery and lowers the cost of therapy to the patient.
Non-alcoholic fatty liver disease (NAFLD) is associated with an increased incidence of osteoporosis and bone fractures
Authors: Loosen Sven H. , Roderburg Christoph , Kostev Karel , Luedde Tom , Demir Münevver , Qvartskhava Natalia , Keitel Verena
Published: October 2021

Background Non-alcoholic fatty liver disease (NAFLD) and osteoporosis are common diseases with a rising incidence worldwide. Both diseases occur in similar patient populations, however, data on their mutual influence are conflicting. Here, we aimed to evaluate the impact of NAFLD on the incidence of osteoporosis and fractures by using the Disease Analyzer database featuring data on diagnoses, prescriptions, and demographic aspects of 7.49 million cases followed in general practices in Germany.

Methods A total of 50,689 patients with NAFLD diagnosed between 2000 and 2015 were matched by age, sex, index year, and 3 comorbidities (obesity, diabetes mellitus, and vitamin D/calcium deficiency) to a cohort of equal size without NAFLD. Incidence of osteoporosis and bone fractures were compared between both groups within 10 years from the index date.

Results Within the observation period, the incidence of osteoporosis was significantly higher in the NAFLD group (6.4%) compared to patients without NAFLD (5.1%; log-rank, p < 0.001). Similar results were observed for bone fractures (12.6 vs. 10.3 %; log-rank p < 0.001). The difference was more pronounced in women compared to men and observed in all age groups >50 years of age.

Conclusion Our data show that NAFLD is significantly associated with osteoporosis as well as bone fractures in a large cohort of patients followed in German general practices. This finding suggests that NAFLD patients might benefit from improved monitoring for the occurrence of bone demineralization and osteoporosis, which in turn could trigger preventive therapeutic measures.
Effekte einer ambulanten Kompaktrehabilitation auf körperliche Leistungsfähigkeit und Lebensqualität bei Patienten mit Berufskrankheiten der Lunge
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Authors: Oldenburger Alexander , Teschler Helmut , Teschler Sebastian , Ernst Friedrich , Goergens Andreas
Published: October 2021

In Deutschland findet die Lungenrehabilitation (PR) traditionell in Rehabilitationskliniken statt. Nach der aktuellen deutschen Richtlinie „Diagnostik und Beurteilung asbestbedingter Berufskrankheiten“ kann PR auch als ambulantes Programm mit den wesentlichen Elementen der stationären PR (Kompakt-Rehabilitation [KR]) angeboten werden. Unser Projekt untersuchte die Auswirkungen der KR auf Akzeptanz, körperliche Leistungsfähigkeit und Lebensqualität bei Patienten mit berufsbedingten Lungenerkrankungen. KR umfasste 24 Einheiten à 90 Minuten mit Physiotherapie und Atemtherapie sowie gerätegestütztes Kraft- und Ausdauertraining. Ziel unserer Studie war es, die Auswirkungen der KR bei Patienten mit Berufskrankheiten der Atemwege und einem gesetzlich verankerten Recht auf PR zu untersuchen. Eine Randomisierung war daher nicht geplant. 148 versicherte Personen mit einer bestätigten beruflichen Erkrankung der Lunge wurden von den Berufsgenossenschaften zur Teilnahme eingeladen. 126 Patienten (85 %) nahmen die Einladung an, und 78 Teilnehmer (Durchschnittsalter 71 Jahre) schlossen das gesamte Programm ab (53 %). Gutartige asbestbedingte Erkrankungen (Plaques, Pleuraverdickungen, Asbestose) dominierten mit rund 80 %. Gebrechlichkeit, Depression und Demenz sind typische Hindernisse. Unter strikter Einhaltung der gewählten Einschluss- und Ausschlusskriterien und Trainingsbedingungen traten keine unerwünschten Ereignisse auf. Die Messergebnisse am Beginn der KR wurden mit denen bei Beendigung verglichen. KR führte zu einer signifikanten (p < 0,01) Verbesserung aller Parameter der körperlichen Leistung: 6-Minuten-Gehtest: + 36 m, Ergometertest: + 9 Watt, Handdynamometrie: + 29 N, Quadriceps-Krafttest: + 84 MKI. Die Inspirationskapazität der Atemmuskulatur (Pimax: + 1,1 kPa) verbesserte sich ebenfalls (p < 0,01). Der SF-36 zeigte eine Verbesserung der Lebensqualität (p < 0,05) in den Subdomänen „geistiges Wohlbefinden“ (+ 3,7) und „körperliche Rollenfunktion“ (+ 4,2). Somit erweist sich die KR unter Berücksichtigung der gewählten Einschluss- und Ausschlusskriterien als sichere und effektive Therapie. KR wird von Patienten ohne schwere Komorbiditäten weithin akzeptiert und erzielt positive Effekte, die mit denen vergleichbar sind, die in Rehabilitationskliniken nachgewiesen wurden. Ambulante KR eignet sich daher zur Behebung des Mangels an strukturierten und zertifizierten Rehabilitations- und Schulungsangeboten in Rehabilitationskliniken und zur Verstetigung der dort erzielten Effekte für versicherte Patienten mit berufsbedingten Atemwegs- und Lungenerkrankungen.
Peroral endoscopic myotomy for management of cricopharyngeal bars (CP-POEM): a retrospective evaluation
Authors: Al Ghamdi Sarah S. , Bejjani Michael , Hernández Mondragón Oscar V. , Parsa Nasim , Yousaf Muhammad N. , Aghaie Meybodi Mohammad , Ghandour Bachir , Krustri Chonlada , Phalanusitthepha Chainarong , Ngamruengphong Saowanee , Nieto Jose M. , Khashab Mouen A.
Published: October 2021

Background Cricopharyngeal bars (CPBs) are a unique etiology of oropharyngeal dysphagia. Symptomatic patients are managed with endoscopic dilation or surgical myotomy. Cricopharyngeal peroral endoscopic myotomy (CP-POEM) is an emerging technique for the management of dysphagia due to CPBs. This study evaluated technical success, clinical success, adverse events, and long-term recurrence following CP-POEM.

Methods Consecutive patients who underwent POEM for management of CPBs between May 2015 and December 2020 at four tertiary care centers were included. Primary outcome was clinical success (defined as improvement of dysphagia score to ≤ 1). Secondary outcomes were technical success, rate and severity of adverse events, procedure duration, and symptom recurrence.

Results 27 patients (mean age 69 years; 10 female) underwent CP-POEM during the study period. The most common presenting symptoms at the time of index procedure were dysphagia (26; 96.3 %) and regurgitation (20; 74.1 %). Clinical and technical success were achieved in all patients. Mild/moderate adverse events occurred in two patients (7.4 %). CP-POEM significantly reduced the median dysphagia score.

Conclusions CP-POEM was a safe and effective treatment for symptomatic CPBs. Although symptom recurrence was low, long-term outcome data are needed. CP-POEM should be considered as a management option for symptomatic CPBs at centers with POEM expertise.