bluuebunny/crossref_metadata_2025 huggingface dataset:
Calreticulin Mutations in Myeloproliferative Neoplasms Patients Diagnosed in UKM Medical Centre
Authors: Zulhimi Ahmad , Azma Raja Zahratul , Izapri Ziqrill , Jalil Norunaluwar , Ithnin Azlin , Tumian Rafeah
Published: June 2023

Introduction: Calreticulin (CALR) mutations are one of the molecular markers that has been incorporated for the diagnosis of myeloproliferative neoplasms (MPN) in the revised 2017 WHO Classification of Haematopoietic and Lymphoid Tumors. This study was performed to determine the prevalence of CALR mutations in patients with MPN diagnosed in UKMMC and to compare their demographics plus laboratory features with other MPN patients. Meth-
ods: A total of 59 MPN patients who tested negative for JAK2V617Fmutation were selected and 21 MPN patients positive for JAK2V617F were included as controls. Screening for CALR exon 9 was done by multiplex polymerase chain reaction (PCR) followed by Sanger sequencing. Results: A total of six JAK2 V617F negative MPN samples were found to be positive for CALR mutations. Out of these six, three patients with CALR mutations were of type I mutation, two were type II while one was a mutation in the stretch III region. None of the twenty one JAK2 V617F positive MPN samples were positive for CALR mutation. Clinical phenotypes for those positive for CALR were restricted to Essential Thrombocythemia (ET), Primary Myelofibrosis (PMF) and one case of atypical Chronic Myeloid Leukaemia (CML). Conclusion: CALR mutations constituted 10.16% from the MPN patients who were negative for JAK2V617F mutation with no significant differences in platelet counts, hemoglobin (Hb), hematocrit and white cell counts as compared to MPN patients with JAK2 V617F mutations. Testing for CALR mutations among those who are negative for JAK2V617F within Malaysian population maybe worthwhile and require larger scale studies.
Let’s Have a Chat! A Conversation with ChatGPT: Technology, Applications, and Limitations
Authors: Shahriar Sakib , Hayawi Kadhim
Published: June 2023

The advent of artificial intelligence-empowered chatbots capable of constructing human-like sentences and articulating cohesive essays has captivated global interest. This paper provides a historical perspective on chatbots, focusing on the technology underpinning the Chat Generative Pre-trained Transformer, better known as ChatGPT. We underscore the potential utility of ChatGPT across a multitude of fields, including healthcare, education, and research. To the best of our knowledge, this is the first review that not only highlights the applications of ChatGPT in multiple domains but also analyzes its performance on examinations across various disciplines. Despite its promising capabilities, ChatGPT raises numerous ethical and privacy concerns that are meticulously explored in this paper. Acknowledging the current limitations of ChatGPT is crucial in understanding its potential for growth. We also ask ChatGPT to provide its point of view and present its responses to several questions we attempt to answer.
 
Received: 5 April 2023 | Revised: 23 May 2023 | Accepted: 29 May 2023
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.
TUNABLE RADIO FREQUENCY (RF) RECEIVER (RX) INTEGRATED CIRCUIT (IC)
Authors: KAZANCI Hüseyin , ORAL Okan
Published: June 2023

In this work tunable radio frequency (RF) receiver (Rx) integrated circuit (IC) was demonstrated. TSMC 65 nm technology node was selected to implement IC. RF technique has some advantages over biomedical optic molecule investigation methods since it is easy to design, implement. Experimental measurement on live tissue is much easier than optic methods. Nanoscopic creatures have specific binding structures. Their elements construct their shapes and neighborhood conformation between their own atoms. Based on this work differential RF waves will be used to investigate the nanoscopic creatures. Since the investigation of nanoscopic creatures will require to use electromagnetic wave phase shift and scan of different RF frequencies, ultra-wide band (UWB) tunable receiver circuit topology was designed and simulated. For this purpose, Rx block was designed, and simulation work was demonstrated here. In the circuit simulations, off-chip antenna was connected to the low-noise amplifier (LNA) circuit. Specific frequency was around 30 GHz. Frequency tuning was adjusted by changing the source and bias voltages at the active inductor voltage-controlled oscillator (VCO) circuit block. The same VCO block was also used at the Tx circuit before. Antenna signal was modeled by using 33 GHz alternative sinusoidal signal. Antenna signal and 30 GHz active-inductor VCO voltage output were mixed at the mixer circuit block, 3 GHz envelope signal was extracted in this work. Layout implementation of Rx receiver IC was demonstrated.
The role of work life balance in the effect of boundaryless career and protean career attitudes on subjective career success
Authors: KURTULDU Selver , ÖZÇELİK Ayşe Oya
Published: June 2023

In conjunction with the rise of new career approaches such as boundaryless career and protean career in today's working life, the subjective aspect of career success has begun to be emphasized in boundaryless career and protean career approaches, unlike the traditional career approach that emphasizes the objective aspect of career success. In this direction, the effect of boundaryless career and protean career attitudes on subjective career success was examined in this study. In addition, whether the work-life balance has a moderator role on this effect has been examined. Research data were collected from 400 white-collar employees who work in private sector enterprises in Istanbul and have at least five years of work experience. To test the hypotheses; hierarchical regression analysis was performed using the SPSS program. As a result of the study, the moderator role of work-life balance on the effect of boundaryless career attitude and protean career attitude on subjective career success has been determined.
IoT-Based IV Infusion Control System
Authors: Prathmesh Nandurkar  , Rahul Khandelwal  , Ruchika Suryawanshi  , S. V. Tathe
Published: June 2023

In current medical care system, monitoring patients in a hospital throughout the day is tiresome. Doctors and Nurses are loaded in monitoring multiple patients. This causes many problems. The health-related work should be properly done and that too in an accurate manner. An example of such type of work in the hospital is injecting saline or Intravenous (IV) fluids into the vein of the patient. If the drip system is not monitored on time, it will cause problems like backflow of fluid, blood loss, etc. In order to reduce the workload and overcome such a critical situation in the area of an intravenous drip monitoring system, we proposed a system called IoT Based IV Infusion System. This Project emphasizes monitoring Intravenous fluid (IV) using a load cell and solenoid valves. Intravenous therapy is a typical method of treatment that may be used for better modification of electrolyte imbalances in the body, to deliver medications, for transfusion of blood, or for fluid injection. The proposed method reduces the difficulties involved in IV therapy and monitoring patient parameters remotely on a webpage
How Putin's Cyberwar Failed in Ukraine
Authors: Givens Austen D. , Gorbachevsky Max , Biernat Anita
Published: June 2023

As Russian military forces surged across the Ukrainian border in February 2022, cybersecurity analysts shared predictions about the ways in which the Russian government would use cyberattacks to thwart Ukrainian defenses. Some government agencies and private sector organizations forecast that the Russians would launch a blitz of devastating electronic attacks against Ukrainian critical infrastructure targets, such as electrical power plants and air traffic control networks, crippling the country. While Russian cyberattacks have played a role in the conflict, their effects to date have been significantly less than what some analysts anticipated. But why? This article examines how analysts’ most extreme predictions about Russia’s use of cyberattacks in Ukraine missed the mark, links these findings to the literatures on military and intelligence forecasting, and offers recommendations for additional research.
Combining Frameworks to Improve Military Health System Quality and Cybersecurity
Authors: Schafer Dr. Maureen L , Schafer Dr. Joseph
Published: June 2023

Existing conceptual frameworks and commercially available technology could be considered to rapidly operationalize the use of Quality Measures (QM) within military health systems (Costantino et al. 2020). Purchased healthcare as well as digital healthcare services have paved the way for data collection from multiple information systems thus offering stakeholders actionable intelligence to both guide and measure healthcare outcomes. However, the collection of data secondary to Smart Devices, disparate information systems, cloud services, and the Internet of Medical Things (IOMT) is a complication for security experts that also affect clients, stakeholders, organizations, and businesses delivering patient care. We have combined three conceptual frameworks: (1) Donabedian’s Quality Attributes Framework (DQA), (2) The National Academy of Medicine (NAM) framework, and the (3) Healthcare and Public Health (HPH) Cybersecurity Framework (HCF). Each of these frameworks is well-tested, widely accepted, and referenced as the gold standard in delivering quality care (DQA and NAM) and cybersecurity (HCF) for healthcare. Separately, each framework provides long-used analysis, guidance, and application of quality reliable measures of healthcare services. The combined frameworksmay enhance data integrity (collection and standardized safety of data in regard to regulatory compliance). The combined frameworks also support identifying gaps in quality of care, support the prioritization of cost-effective methodologies that predictably improve patient outcomes, and support DHA’s quality measures. Finally, we offer the importance of understanding the components of quality measures in a more precise manner while maintaining information technology (IT) governance compliance.
UPAYA KEBANGKITAN UMKM KUE MOCI “NAJAH” PASCA PANDEMI COVID-19 MELALUI STRATEGI PEMASARAN DI KOTA SEMARANG
Authors: Yani Tri Endang , Wibisono Totok , Roestanto Anantya
Published: June 2023

Sejak awal tahun 2020 di seluruh dunia terjadi pandemi covid-19. Hal tersebut sangat berdampak buruk bagi seluruh sendi kehidupan manusia,  tidak hanya di bidang kesehatan, akan tetapi juga di bidang sosial, politik, teknologi, dan juga dibidang ekonomi. Salah satu UMKM  yang terdampak akibat pendemi covid-19 adalah UMKM Kue Moci “Najah”. UMKM ini terpaksa berhenti produksi selama sekitar dua tahun  akibat menurunnya jumlah pembeli. Pada awal tahun 2022,  pandemi covid-19 mereda dan masyarakat diperbolehkan kembali untuk beraktivitas, UMKM ini mulai mencoba bangkit kembali. Akan tetapi penjualan yang diperoleh belum sesuai dengan yang diharapkan. Pengabdian Kepada Masyarakat ini bertujuan membantu UMKM dalam rangka meningkatkan penjualan pasca pandemi Covid-19. Metode pelaksanaan kegiatan pengabdian kepada masyarakat  adalah metode penyuluhan dan pelatihan. Target yang ingin dicapai adalah mitra dapat menerapkan strategi pemasaran yang tepat sehingga dapat meningkatkan penjualan. Setelah dilakukan pengabdian masyarakat, telah terjadi perubahan yang positif pada pelaku UMKM kue moci “Najah” terhadap pengetahuan dan pemahaman dalam strategi memasarkan produk UMKM. Disamping itu Pelatihan yang diberikan dapat menambah ketrampilan bagi pelaku UMKM dalam melakukan pemasaran secara online.
Work-life balance, psychological well-being and factors contributing to academics’ productivity and turn-over intentions during the COVID-19 pandemic
Authors:   , Shange Ellen Mzwakhe
Published: June 2023

Work-life balance is one of the most important criteria for staff satisfaction in any institution. Achieving a good work-life balance is integral to ensuring that your institution is an employer of choice which consequently will ensure that the best employees will be attracted. The same can be said of academia, where having a well-balanced work-life can contribute to attracting, developing, and retaining suitably qualified academics. The aim of this study was to examine the work-life balance and psychological well-being of academics at a selected University of Technology in KwaZulu-Natal, South Africa. The contribution of this study is to establish factors that influence the productivity as well as the turn-over intentions of academics during the COVID-19 pandemic. A quantitative approach was adopted with a structured questionnaire comprising a 5-point Likert Scale was employed to collect the data. The target population consisted of 175 academics of a selected University of Technology in KwaZulu-Natal. A census sampling method was employed for the study because the population size was small, and every member of the population had an equal chance of being selected. Structural Equation Modelling (SEM) techniques were employed in the study to establish the predictive power and reliability of the developed model. The data obtained from the questionnaire was then analysed using AMOS 27 statistical software. The results from the data revealed that 89% of academics still work long hours and have less time to spend with their families and loved ones. This is not ideal for achieving a healthy worklife balance. The results also confirmed that a poor work-life balance influences the productivity of academics negatively, causing poor psychological well-being for them. The literature also supported the fact that without a well-balanced work-life, the productivity will decrease, and turnover intentions will increase for academics. The results obtained from the data also indicated that 20% of the academics in the researched university are still acquiring their minimum qualification required to be in the academia, this is likely to be mirrored within other similar institutions in South Africa.
Teaching English to Young Learners: Combining Theory and Practice through Practicum in Pre-service Teacher Education
Authors: TEKİN Serdar , BAYKARA Tuba
Published: June 2023

Recent years have witnessed an exponential growth in interest in teaching English to young learners (TEYL) across the world. Pivotally, there is some research focusing on in-class practices and teacher pedagogy on this issue, yet young learner teacher education has not been given much attention. Many teacher education programs in different countries prepare their pre-service teachers for young learners by offering TEYL courses without providing them with real classroom experiences. To this end, the researchers initiated a practicum project in which pre-service EFL teachers taught English to young learners besides taking the TEYL module at the university. Drawing on semi-structured interviews with 21 participants, it was aimed to examine the effectiveness of a practicum-integrated TEYL teacher education program. The findings revealed that practicum provided teacher candidates with a range of benefits in terms of putting young learner knowledge into practice, developing teaching skills, designing age-appropriate lessons and materials, and gaining confidence with TEYL. Different from previous practicum-related studies, the current study showed that practicum helped pre-service teachers have clearer minds on their future careers and teaching contexts in that some participants would choose to work with older learners considering the distinctive characteristics of children. This study offers implications for pre-service teachers and teacher education programs for training young learner English teachers more effectively.
VISUAL OUTCOME OF SURGICAL MANAGEMENT OF EYES WITH MACULA INVOLVING OR MACULA THREATENING TRACTIONAL RETINAL DETACHMENT
Authors: QUNDEEL ZAHRA  , HUSSAIN AHMAD KHAQAN  , HADIA JABEEN  , FARRUKH JAMEEL
Published: June 2023

Objectives: To assess and analyze the visual outcome of surgical management in consecutive series of eyes with macula involving or macula threatening tractional retinal detachment

Material and Methods: Sixty five cases of diabetic retinopathy were included who fulfilled the inclusion and exclusion criteria.

Results: The mean ± SD age was 50.97±8.03. The mean duration of diabetes mellitus was 14.68±7.02. Preoperative visual acuity was 6/18, 2(3.1%), 6/24, 6(9.2%), 6/36, 5 (7.6%), 6/60, 11 (16.9%), CF visual acuity was 23 (35.4%) patients, HM was 10, (15.4%) patients and PLPR 8 (12.3%) patients respectively. While postoperative visual acuity after 6 months was 6/12, 2(3.1%), 6/18, 7 (10.8%), HM 4 (6.2%), PLPR 6 (9.2%) and 2 (3.1%) patients had NPL which is statistically significant (p <0.02).

Conclusion: Major complications are rare after vitrectomy for advanced proliferative diabetic retinopathy, and >70% of eyes regain vision of 6/60 or better.
OUTCOME OF UNREAMED INTERLOCKING NAIL IN OPEN FRACTURES OF TIBIA
Authors: ZUBAIR KARIM  , INAM ULLAH  , NAVEED
Published: June 2023

This study was undertaken to investigate the outcome of unreamed interlocking nail in open fractures of tibia in our setup. sixty cases of open tibial diaphyseal fractures were treated with unreamed intramedullary interlocking nail. The cases were followed up for a period of nine months and data regarding, infection, union, delayed union and nonunion was recorded. In our study union occurred in 50 (83.3%) patients within 5 months, delayed union in 9 (15 %) patients and nonunion in 1 (1.7%) patient after course of follow-up. Infection was observed in 8 (13.3%) cases while 52 (86.7%) cases did not show any sign of infection. Because of the high union rate and low infection rate, we consider unreamed interlocking nailing of tibial fractures as the best mode of treatment for open diaphyseal tibial fractures.
DIAGNOSTIC ACCURACY OF HEPATIC TUMOR INDEX ON DOPPLER SONOGRAPHY FOR THE DIAGNOSIS OF HEPATOCELLULAR CARCINOMA
Authors: ABDUS SAMI QAZI  , MUHAMMAD WASIF IQBAL  , MUHAMMAD AWAIS QAZI AS  , IQBAL MW  , AWAIS M
Published: June 2023

Objective: The purpose of this study was to determine the Diagnostic Accuracy of Hepatic Tumor Index (HTI) on Doppler Sonography for the diagnosis of Hepatocellular carcinoma (HCC) while differentiating it from other very closely resembling pathologic lesions like Metastases and Hepatic hemangiomas.

Material and Methods: The study was held in the Department of Diagnostic Radiology, Lahore General Hospital, Lahore. All patients included in the study were within the ages of 20-70 years and from both genders who attended indoor and outpatient departments from June 2012 to June 2013. Color Doppler Ultrasonography (CDUS) was done on 105 patients with irregular hepatic lesions less than 03 cm in diameter. The HTI was estimated as the ratio of the tumoral peak systolic velocity (PSV) to the PSV of the right or left hepatic artery. The results of Doppler Sonography and Histopathology were compared taking Histopathology as gold standard.

Results: Out of 105 positive cases, the HTI was 1.0 or greater in 91 cases suggesting that those patients had hepatoma while HTI was less than 1.0 in 14 cases suggesting such patients to be harboring tumors other than hepatocellular carcinoma (HCC). Hence in hepatic lesions a tumoral PSV equal to or greater than 0.40 m/sec and HTI equal to 1.0 or greater was related with 97.78 % sensitivity, 80% specificity , 96.70 % positive predictive value, 85.71 % negative predictive value and 95.23 % diagnostic accuracy in differentiating HCC from hepatic metastases and hemangiomas. Conclusion: The HTI on CDUS is useful in differentiating HCC from other hepatic lesions especially hepatic metastases or hemangiomas. We strongly recommend CDUS for the evaluation of HCC because it is highly accurate, easily available and non-invasive imaging modality for its diagnosis.
Quantification of oil and gas methane emissions in the Delaware and Marcellus basins using a network of continuous tower-based measurements
Authors: Barkley Zachary , Davis Kenneth , Miles Natasha , Richardson Scott , Deng Aijun , Hmiel Benjamin , Lyon David , Lauvaux Thomas
Published: June 2023

Abstract. According to the United States Environmental Protection Agency (US EPA), emissions from oil and gas infrastructure contribute 30 % of all anthropogenic methane (CH4) emissions in the US. Studies in the last decade have shown emissions from this sector to be substantially larger than bottom-up assessments, including the EPA inventory, highlighting both the increased importance of methane emissions from the oil and gas sector in terms of their overall climatological impact and the need for independent monitoring of these emissions. In this study we present continuous monitoring of regional methane emissions from two oil and gas basins using tower-based observing networks. Continuous methane measurements were taken at four tower sites in the northeastern Marcellus basin from May 2015 through December 2016 and five tower sites in the Delaware basin in the western Permian from March 2020 through April 2022. These measurements, an atmospheric transport model, and prior emission fields are combined using an atmospheric inversion to estimate monthly methane emissions in the two regions. This study finds the mean overall emission rate from the Delaware basin during the measurement period to be 146–210 Mg CH4 h−1 (energy-normalized loss rate of 1.1 %–1.5 %, gas-normalized rate of 2.5 %–3.5 %). Strong temporal variability in the emissions was present, with the lowest emission rates occurring during the onset of the COVID-19 pandemic. Additionally, a synthetic model–data experiment performed using the Delaware tower network shows that the presence of intermittent sources is not a significant source of uncertainty in monthly quantification of the mean emission rate. In the Marcellus, this study finds the overall mean emission rate to be 19–28 Mg CH4 h−1 (gas-normalized loss rate of 0.30 %–0.45 %), with relative consistency in the emission rate over time. These totals align with aircraft top-down estimates from the same time periods. In both basins, the tower network was able to constrain monthly flux estimates within ±20 % uncertainty in the Delaware and ±24 % uncertainty in the Marcellus. The results from this study demonstrate the ability to monitor emissions continuously and detect changes in the emissions field, even in a basin with relatively low emissions and complex background conditions.
Monsoon-driven changes in aeolian and fluvial sediment input to the central Red Sea recorded throughout the last 200,000 years
Authors: Ehrmann Werner , Wilson Paul A. , Arz Helge W. , Schulz Hartmut , Schmiedl Gerhard
Published: June 2023

Abstract. Climatic and associated hydrological changes controlled the transport processes and composition of the sediments in the central Red Sea during the last ca. 200 kyr. Three different source areas for mineral dust are identified. The dominant source is located in the eastern Sahara (Sudan and southernmost Egypt). We identify its imprint on Red Sea sediments by high smectite and Ti contents, high 87Sr/86Sr and low εNd. The availability of deflatable sediments was controlled by the intensity of tropical rainfall and vegetation cover over northern Africa linked to the African monsoon. Intense dust input to the Red Sea occurred during arid phases, low input during humid phases. A second, less significant source indicated by palygorskite input is probably located on the eastern Arabian Peninsula and/or Mesopotamia, while the presence of kaolinite suggests an additional minor dust source in northern Egypt. Our grain size data reflect episodes of fluvial sediment discharge to the central Red Sea and document the variable strength in response to all of the precession-paced insolation maxima during our study interval including both those that were strong enough to trigger sapropel formation in the eastern Mediterranean Sea and those that were not. The African Humid Period most strongly expressed in our Red Sea record was the one during the Eemian last interglacial at ca. 125 ka, followed by those at 198 ka, 108 ka, 84 ka and 6 ka.
Measurements of VOCs in ambient air by Vocus PTR-TOF-MS: calibrations, instrument background corrections, and introducing a PTR Data Toolkit
Authors: Jensen Andrew R. , Koss Abigail R. , Hales Ryder B. , de Gouw Joost A.
Published: June 2023

Abstract. Volatile organic compound (VOC) emissions and subsequent oxidation contribute to the formation of secondary pollutants and poor air quality in general. As more VOCs at lower mixing ratios have become the target of air quality investigations, their quantification has been aided by technological advancements in proton-transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS). However, such quantification requires appropriate instrument background measurements and calibrations, particularly for VOCs without calibration standards. This study utilized a Vocus-PTR-TOF-MS to measure ambient VOCs in Boulder, Colorado during spring 2021. Fast, frequent calibrations were made every 2 h in addition to daily multipoint calibrations. Sensitivities derived from the fast calibrations were 5±6 % (average and one standard deviation) lower than those derived from the multipoint calibrations due to an offset between the calibrations and instrument background measurement. This offset was caused, in part, by incomplete mixing of the standard with diluent. These fast calibrations were used in place of a normalization correction to account for variability in instrument response and accounted for non-constant reactor conditions caused by a gradual obstruction of the sample inlet. One symptom of these non-constant conditions was a trend in fragmentation, although the greatest observed variability was 6 % (one relative standard deviation) for isoprene. A PTR Data Toolkit (PTR-DT) was developed to assess instrument performance and rapidly estimate the sensitivities of non-standard VOCs on the timescale of the fast calibrations using the measured sensitivities of standards, molecular properties, and simple reaction kinetics. Through this toolkit, the standards’ sensitivities were recreated within 1±8 % of the measured values. Three clean air sources were compared: a hydrocarbon trap, zero grade air and ultra-high purity nitrogen, and a catalytic zero-air generator. The catalytic zero-air generator yielded the lowest instrument background signals for the majority of ions, followed by the hydrocarbon trap. Depending on the ionization efficiency, product ion fragmentation, ion transmission, and instrument background, standards’ limits of detection (5-s measurement integration) derived from the catalytic zero-air generator and the fast calibration sensitivities ranged from 2 ppbv (methanol) to 1 pptv (decamethylcyclopentasiloxane; D5 siloxane) with most standards having detection limits below 20 pptv. Finally, applications of measurements with low detection limits are considered for a few low-signal species related to cooking emissions, volatile cyclic methyl siloxanes, and organosulfur compounds.
Earth's core variability from the magnetic and gravity field observations
Authors: Saraswati Anita Thea , de Viron Olivier , Mandea Mioara
Published: June 2023

Abstract. The motions of the liquid within the Earth's outer core lead to magnetic field variations together with mass distribution changes. As the core is not accessible to direct observation, our knowledge of the Earth’s liquid core dynamics only relies on indirect information sources. Mainly generated by the core dynamics, the surface geomagnetic field provides information about the variations of the fluid motion at the top of the core. The dynamic of the fluid core is also associated with mass distribution changes inside the core, and produces gravitational field time fluctuations. By applying several statistical Blind Source Separation methods to both the gravity and magnetic field time series, we investigate the common space-time variabilities. We report several robust interannual oscillations shared by the two observation sets. Among those, a common mode of around 7 years looks very significant. Whereas the nature of the driving mechanism of the coupled variability remains unclear, the spatial and temporal properties of the common signal are compatible with a core origin.
East Asia Reanalysis System (EARS)
Authors: Yin Jinfang , Liang Xudong , Xie Yanxin , Li Feng , Hu Kaixi , Cao Lijuan , Chen Feng , Zou Haibo , Zhu Feng , Sun Xin , Xu Jianjun , Wang Geli , Zhao Ying , Liu Juanjuan
Published: June 2023

Abstract. Reanalysis data play a vital role in weather and climate study as well as meteorological resource development and application. In this work, the East Asia Reanalysis System (EARS) was developed using the Weather
Research and Forecasting (WRF) model and the Gridpoint Statistical
Interpolations (GSI) data assimilation system. The regional reanalysis
system is forced by the European Centre for Medium-Range Weather Forecasts (ECMWF) global reanalysis ERA-Interim data at 6 h intervals. Hourly surface observations are assimilated by the Four-Dimension Data Assimilation (FDDA)
scheme during the WRF model integration; upper observations are assimilated
in three-dimensional variational data assimilation (3D-VAR) mode at the analysis moment. It should be highlighted that many of the assimilated observations have not been used in other reanalysis systems. The reanalysis
runs from 1980 to 2018, producing a regional reanalysis dataset covering
East Asia and surrounding areas at 12 km horizontal resolution, 74 sigma
levels, and 3 h intervals. Finally, an evaluation of EARS has been
performed with respect to the root mean square error (RMSE), based on the 10-year (2008–2017) observational data. Compared to the global
reanalysis data of ERA-Interim, the regional reanalysis data of EARS are closer to the observations in terms of RMSE in both surface and
upper-level fields. The present study provides evidence for substantial
improvements seen in EARS compared to the ERA-Interim reanalysis fields over
East Asia. The study also demonstrates the potential use of the EARS data
for applications over East Asia and proposes further plans to provide the
latest reanalysis in real-time operation mode. Simple data and updated
information are available on Zenodo at
https://doi.org/10.5281/zenodo.7404918 (Yin et al., 2022), and the full
datasets are publicly accessible on the Data-as-a-Service platform of the China Meteorological Administration (CMA) at http://data.cma.cn (last access: 19 May 2023).
Planning a geostatistical survey to map soil and crop properties: eliciting sampling densities
Authors: Chagumaira Christopher , Chimungu Joseph G. , Nalivata Patson C. , Broadley Martin R. , Milne Alice E. , Lark R. Murray
Published: June 2023

Abstract. The communication of uncertainty is not only a challenge when soil information has been produced but also in the planning stage. When planning a survey of soil properties it is necessary to make decisions about the sampling density. Sampling density determines both the quality of predictions and the cost of fieldwork. In this study, we considered four ways in which the relationship between sample density and the uncertainty of predictions can be related, based on prior information about the variability of the target quantity. These were offset correlation, prediction intervals, conditional probabilities of the interpretation errors and implicit loss functions. Offset correlation is a measure of the consistency of kriging predictions made from sample grids with the same spacing but different origins. Prediction intervals and conditional probabilities are based on the prediction distribution of the variable of interest. All four of these methods were investigated using the information on soil pH and Se concentration in grain in Malawi. They were presented to a group of stakeholders, who were asked to use them in turn to select a sampling density. Their responses were evaluated and they were then asked to rank the methods based on their effectiveness, in their experience, and in terms of finding a level of uncertainty that they were able to tolerate when deciding about a sampling grid spacing. Our results show that the approach that stakeholders favoured was offset correlation, and some approaches were not well understood (conditional probability and implicit loss function). During feedback sessions, the stakeholders highlighted that they were more familiar with the concept of correlation, with a closed interval of [0,1] and this explains the more consistent responses under this method. The offset correlation will likely be more useful to stakeholders, with little or no statistical background, who are unable to express their requirements of information quality based on other measures of uncertainty.
MEDFATE 2.9.3: a trait-enabled model to simulate Mediterranean forest function and dynamics at regional scales
Authors: De Cáceres Miquel , Molowny-Horas Roberto , Cabon Antoine , Martínez-Vilalta Jordi , Mencuccini Maurizio , García-Valdés Raúl , Nadal-Sala Daniel , Sabaté Santiago , Martin-StPaul Nicolas , Morin Xavier , D'Adamo Francesco , Batllori Enric , Améztegui Aitor
Published: June 2023

Abstract. Regional-level applications of dynamic vegetation models are challenging because they need to accommodate the variation in plant functional
diversity, which requires moving away from broadly defined functional types. Different approaches have been adopted in the last years to incorporate
a trait-based perspective into modeling exercises. A common parametrization strategy involves using trait data to represent functional variation
between individuals while discarding taxonomic identity. However, this strategy ignores the phylogenetic signal of trait variation and cannot be
employed when predictions for specific taxa are needed, such as in applications to inform forest management planning. An alternative strategy
involves adapting the taxonomic resolution of model entities to that of the data source employed for large-scale initialization and estimating
functional parameters from available plant trait databases, adopting diverse solutions for missing data and non-observable parameters. Here we
report the advantages and limitations of this second strategy according to our experience in the development of MEDFATE (version 2.9.3), a novel
cohort-based and trait-enabled model of forest dynamics, for its application over a region in the western Mediterranean Basin. First, 217 taxonomic
entities were defined according to woody species codes of the Spanish National Forest Inventory. While forest inventory records were used to obtain
some empirical parameter estimates, a large proportion of physiological, morphological, and anatomical parameters were matched to measured plant
traits, with estimates extracted from multiple databases and averaged at the required taxonomic level. Estimates for non-observable key parameters
were obtained using meta-modeling and calibration exercises. Missing values were addressed using imputation procedures based on trait covariation,
taxonomic averages or both. The model properly simulated observed historical changes in basal area, with a performance similar to an empirical model
trained for the same region. While strong efforts are still required to parameterize trait-enabled models for multiple taxa, and to incorporate
intra-specific trait variability, estimation procedures such as those presented here can be progressively refined, transferred to other regions or
models and iterated following data source changes by employing automated workflows. We advocate for the adoption of trait-enabled and
population-structured models for regional-level projections of forest function and dynamics.
Seismogenic potential and tsunami threat of the strike-slip Carboneras fault in the western Mediterranean from physics-based earthquake simulations
Authors: Álvarez-Gómez José A. , Herrero-Barbero Paula , Martínez-Díaz José J.
Published: June 2023

Abstract. Strike-slip fault ruptures have a limited capacity to generate vertical deformation, and for this reason they are usually dismissed as potential destructive tsunami sources. At the western tip of the western Mediterranean, in the Alboran Sea, tectonics is characterized by the presence of large transcurrent fault systems and minor reverse and normal faults in a zone of diffuse deformation. The strike-slip Carboneras fault is one of the largest sources in the Alboran Sea and therefore with the greatest seismogenic capacity. It is also one of the active structures with higher slip rates in the eastern Betic fault zone and has been proposed as the source of the damaging 1522 (M 6.5; Int. VIII–IX) Almeria earthquake. The dimensions and location of the Carboneras fault imply a high seismic and tsunami threat. In this paper we present tsunami simulations from seismic sources generated with physics-based earthquake simulators. We have generated a 1 Myr synthetic seismic catalogue consistent on 773 893 events, with magnitudes ranging between Mw 3.3 and 7.6. From these events we have selected those sources producing a potential energy capable of generating a noticeable tsunami, those sources being earthquakes with magnitudes ranging from 6.71 to 7.62. The Carboneras fault has the capacity to generate locally damaging tsunamis; however, on a regional scale its tsunami threat is limited. The frequency–magnitude distribution of the generated seismic catalogue reflects the variability of magnitudes associated with the rupture of the entire fault, departing the upper limit from the classical Gutenberg–Richter potential relation. The inter-event time for the maximum earthquake magnitudes is usually between 2000 and 6000 years. The use of physics-based earthquake simulations for tsunamigenic sources allows an in-depth characterization of the scenarios, allowing a qualitative leap in their parametrization.
Quantification and correction of motion influence for nacelle-based lidar systems on floating wind turbines
Authors: Gräfe Moritz , Pettas Vasilis , Gottschall Julia , Cheng Po Wen
Published: June 2023

Abstract. Inflow wind field measurements from nacelle-based lidar systems offer great potential for different applications including turbine control, load
validation, and power performance measurements. On floating wind turbines nacelle-based lidar measurements are affected by the dynamic behavior of
the floating foundations. Therefore, the effects on lidar wind speed measurements induced by floater dynamics must be understood. In this work, we investigate the influence of floater motions on wind speed measurements from forward-looking nacelle-based lidar systems mounted on floating
offshore wind turbines (FOWTs) and suggest approaches for correcting motion-induced effects. We use an analytical model, employing the guide for the expression of uncertainty in measurements (GUM) methodology and a numerical lidar simulation for the quantification of uncertainties. It is found that the uncertainty of lidar wind speed estimates is mainly caused by the fore–aft motion of the lidar, resulting from the pitch displacement of the floater. Therefore, the uncertainty is heavily dependent on the amplitude and the frequency of the pitch motion. The bias of 10 min mean wind speed estimates is mainly influenced by the mean pitch angle of the floater and the pitch amplitude. We correct motion-induced biases in time-averaged lidar wind speed measurements with a model-based approach, employing the developed analytical model for uncertainty and bias quantification. Testing of the approach with simulated dynamics from two different FOWT concepts shows good results with remaining mean errors below 0.1 m s−1. For the correction of motion-induced fluctuation in instantaneous measurements, we use a frequency filter to correct fluctuations caused by floater pitch motions for instantaneous measurements. The correction approach's performance depends on the pitch period and amplitude of the FOWT design.
U The Urgensi URGENSI PERLINDUNGAN DATA PRIBADI DALAM PRESPEKTIF HAK ASASI MANUSIA
Authors: Parihin Nela mardiana
Published: June 2023

Perkembangan teknologi informasi yang pesat berdampak pada berbagai aktivitas masyarakat. Meningkatnya jumlah pengguna internet di Indonesia menjadi urgensi bagi keberadaan aturan perlindungan data pribadi di dunia digital. Perlindungan data pribadi merupakan bagian dari perlindungan diri pribadi yang dilindungi dalam pasal 28G ayat (1) Undang-Undang Dasar Negara Republik Indonesia Tahun 1945. Di sisi lain dalam pesatnya teknologi digital serta sudut pandang manusia dalam mengaplikasikan perkembangan teknologi digital ini menimbulkan banyak permasalahan yang sering muncul terkait dengan perlindungan data pribadi. Permasalahan ini muncul karena banyaknya celah pada situs-situs perusahaan ataupun instansi pemerintah yang memudahkan seorang peretas atau hacker untuk membobol data pribadi masyarakat. Regulasi mengenai perlindungan data pribadi dalam lembaga swasta maupun pemerintah telah diatur dalam Undang-Undang Inonesia. Namun implementasinya masih jauh dari kata sempurna untuk memberikan perlindungan data pribadi. Maka dari itu, penelitian ini menganalisis tentang Urgensi Perlindungan Data Pribadi Dalam Prespektif Hak Asasi Manusia. Metode penelitian yang digunakan dalam penelitian ini adalah yuridis normatif dengan pendekatan Undang-Undang (Statute Approach), pendekatan kasus (Case Approach) dan pendekatan perbandingan (Comparative Approach). Tuntutan di era teknologi meningkatkan kejahatan terkait kebocoran data pribadi yang digunakan untuk kepentingan komersil individu atau kelompok tertentu. Hal ini perlu diperhatikan karena sangat merugikan dan melanggar privasi masyarakat. Penggunaan data pribadi harus diimbangi dengan perlindungan data pribadi yang kuat. Dalam praktiknya, ketiadaan Undang-Undang perlindungan data pribadi di Indonesia menyebabkan banyaknya kasus pembobolan data.
Time-Driven Activity-Based Costing of Prosthetic Dental Treatment
Authors: KAÇAK Hakan
Published: June 2023

Purpose: Health systems worldwide have sustainability concerns due to rising demand and healthcare services costs. Value-based healthcare (VBHC) may solve all sustainability challenges by improving health outcomes. Improving outcomes is the only effective approach to cutting healthcare expenses. Cost-assessment methodologies that can give high-quality cost information are required to implement value-based initiatives. Time-driven activity-based costing (TDABC) method, a cost component of VBHC, has been increasingly adopted to close the cost-information gap.
Materials & Methods: The study calculates prosthetic dental treatment costs with the time-driven activity-based costing method. Data for this study were collected from the prosthesis department of a dental hospital in 2019.
Results: The department's total practical capacity was estimated as 1,365,888 min for dentists and 328,320 minutes for patient consultants. The dentist capacity cost rate was calculated as 1.71 TL/min and for a patient consultant as 0.69 TL/min. Total prosthetic dental treatment costs range between 252.7TL and 304TL, depending on complications, emergencies, consultation or sedation needs.
Conclusion: Activity-Based Costing provides accurate cost information and improves the process by making costs and activities more transparent. The prosthetic dental treatment process was presented transparently in the study. The costing model was designed to be expanded concerning the patient's urgency, the consultation and sedation needs. The cost of only one procedure was calculated in the study, and it is planned to evaluate all department activities in future research.
Parestesia do nervo alveolar inferior como resultado da cirurgia de terceiro molar: incidência e fatores de risco
Authors: Cavalcanti Isabela Santos , Moreira Larissa Rodrigues , Fonseca Larissa Dias da , Vale Michele Cristina Silva do , Almeida Sabrina da Silva , Seroli Wagner
Published: June 2023

A lesão potencial do nervo alveolar inferior (NAI) é reconhecida como uma das principais causas de parestesia permanente após a herança dos terceiros molares inferiores. O NAI desempenha um papel crucial na transmissão de estímulos sensoriais e nociceptivos nos dentes inferiores. Compreender a anatomia, localização e características do NAI é fundamental para promover procedimentos cirúrgicos mais seguros, acolher significativamente o risco de complicações iatrogênicas e lesões permanentes. Portanto, o objetivo desta revisão narrativa é explorar as características do NAI, os fatores que podem levar à parestesia e as opções terapêuticas disponíveis. Conclui-se que, existem vários protocolos sugeridos na literatura para o controle e tratamento da parestesia por lesão, ou injúria ao NAI, contudo, é necessário compreender os aspectos anatómicos e funcionais deste nervo com o intuito de prevenir esse tipo de lesão, minimizando as chances de parestesias que podem ser permanentes, ou definitivas.
Heidegger e a Universidade: acerca do vínculo essencial entre ciência e formação
Authors: Doro Marcelo José
Published: June 2023

Este artigo apresenta, como resultado de uma pesquisa bibliográfica, as linhas gerais da crítica de Heidegger à Universidade de seu tempo, marcada pela fragmentação crescente das ciências em disciplinas especializadas e pelo consequente rompimento com um ideal efetivo de formação humana. Além disso, busca estruturar uma compreensão geral da proposta de reforma universitária que o filósofo anuncia no Discurso do reitorado, cujo núcleo é o reestabelecimento da Universidade enquanto espaço privilegiado para a transformação da existência individual e coletiva. A tese de fundo é que Heidegger procura devolver à Universidade o seu papel formativo, já concebido por Humboldt, mas pelo caminho do questionamento ontológico. Guardadas as diferenças contextuais e as transformações que atingiram a instituição universitária desde a época em que Heidegger produziu suas reflexões, na primeira metade do século XX, acredita-se que elas são ainda pertinentes para mobilizar o debate na atualidade.
Amphibolites from the Serbo-Macedonian Massif (Northern Greece)
Authors: Sapountzis Elias , Kassoli-Fournaraki Anna , Christofides Georgios
Published: June 2023

Amphibolites from the Vertiskos and Kerdyllia series of the Serbo-Macedoninn massif, Northern Greece, are examined in terms of their mineralogy and petrochemistry. Evidence based on data derived from the geochemistry and mineral parageneses, indicate that the rocks in study arc of basic igneous origin and have metamorphosed in the amphiboli tefacies. The nature of the parental magma, as deduced from the normative compositions and chemical variation trends is in general of tholeiitic compositi on. Discrimination diagrams based on major and trace elements suggest a possible ocean-floor tectonic affinity.