bluuebunny/crossref_metadata_2025 huggingface dataset:
Accuracy of multiple implant impressions using different combinations of impression materials using closed tray technique
Authors: Deshmukh Madhura , Ahmed Nabeel , Maiti Subhabrata , Rajaraman Vaishnavi
Published: May 2024

Decision for precision! The first stage in creating an accurate, passively fitting prosthesis is to replicate the intraoral relationship of implants using impression methods. The technique and the impression material utilized are the key elements that influence the accuracy of the implant imprint. The goal of this study was to assess the accuracy of the described implant impression technique using various impression materials, as well as to look into the clinical aspects that influence implant impression accuracy. Two holes (4.3 mm × 10 mm) were drilled in a U-shaped study plastic model representing the partially edentulous maxilla, and the appropriate Nobel Biocare Replace select implants were implanted. Closed tray copings were placed for the relevant implants, and closed tray impressions were taken with several impression materials (PVS-1) Dentsply, medium-bodied, and 2) Regular setting-Zhermack Elite HD+). To assess passive fit accuracy, a jig trial and RVG IOPA were used. Stereomicroscopy was used to evaluate the precision of the implant and analog interface from two perspectives: buccal and lingual. On the buccal aspect, Group 1 had a mean value of 13703.29, whereas Group 2 had a mean value of 11395.58. On the lingual aspect, Group 1's mean value was 8415.61, whereas Group 2's was 9192.01. In the closed tray technique, no statistically significant differences between different imprint materials were found. There was no significant difference in the accuracy of closed tray implant impression techniques with different impression materials, according to the findings.
Amylase-producing marine actinobacterium of Micromonospora sp. and their potential antibacterial effects against oral pathogens
Authors: Pradeep Rajasri , Sivaperumal Pitchiah , Roy Anitha
Published: May 2024

Marine actinobacteriological investigation is still in its beginning in India. Earlier, in the 20th century, studies on Actinobacteria were started and highly concentrated on diversity, identification, and screening for enzymes, antibiotics, and enzyme inhibitors. With the spurge of infectious diseases requiring antibiotics, novel antibiotics are in search as the prevalent ones have declined uses, due to the antibiotic-resistant microbial growth. Unexploited ecosystems are studied for isolation of rare species such as Actinobacteria which are expected to yield newer metabolites. The marine actinobacterial isolation and enumeration were done from sediment samples. The marine Actinobacteria were identified by conventional methods. Further amylase enzyme production and their antibacterial activities are also done following the standard methods. The Micromonospora sp. was identified by chemotaxonomical characteristics and spore chain morphology. Further, the amylase enzyme production was done and quantification of enzyme also done. The potential antimicrobial activity from the amylase enzyme was done. Zone of inhibition and minimal inhibitory concentration were calculated. It concluded that potent antibacterial activity was obtained from Actinobacteria
Micromonospora sp. producing amylase enzymes.
Extracellular polymeric substances from marine actinobacterium of Micromonospora sp. and their antioxidant activity
Authors: George Rinki Susan , Sivaperumal Pitchiah , Roy Anitha
Published: May 2024

Actinobacteria, Gram-positive bacteria are the largest phyla among the major species in the bacteria domain. Micromonospora sp. is one of the secondary metabolite-producing Actinobacteria, and it has a comprehensive spectrum of antibacterial, antifungal, antitumor, antiviral, antiparasitic, diabetogenic anti-inflammatory, insecticidal, inhibitory of enzyme, antioxidant, and other biological activities. The objective of the study is to assess the antioxidant activity of the Actinobacterium
Micromonospora sp. producing extracellular polymeric substances (EPSs). Enumeration and isolation of Actinobacteria from sediment samples are done. The marine Actinobacteria, Micromonospora sp. are identified by melanoid pigments and other chemotaxonomical characteristics. EPS is produced from the potential marine Actinobacteria and their components are estimated. The total antioxidant value is found for the EPS. The antioxidant activity of the ascorbic acid equivalent which was 142.65 μg/ml was equivalent to 150 μg/ml of the total antioxidant activity of the EPS produced. The role of different antioxidants and the action in different diseases were challenged since they could act as many mechanisms such as reducing power, providing hydrogen to radicals, and scavenging activity (free radical). To conclude, the potent antioxidant activity was obtained from Actinobacteria
Micromonospora sp. producing extracellular substances. These extracts might bear anticancer metabolites and are considered a potent anticancer drug.
Antioxidant activities from melanin pigment produced by marine actinobacterium of Streptomyces species
Authors: Sheefaa M. I. , Sivaperumal Pitchiah
Published: May 2024

Melanin is macromolecules which have been developed while oxidative polymerization of phenolic compounds. It has been found that the majority of marine organisms produce melanin pigment. To obtain the melanin from marine actinobacteria and their biological properties are studied. Isolation and identification of marine actinobacteria were carried out using the media of ISP-1, ISP-7. Spore chain morphology, chemotaxonomic characteristics were also analyzed by the International Streptomyces Project. The antioxidant activities of DPPH, lipid peroxide using actinobacterial melanin were determined. The Streptomyces species have the capacity to produce melanin pigments and it shows potential antioxidant properties. When DPPH concentrations were compared with the ascorbic acid standard, the melanin of 150 μg/ml showed 93.47% of scavenging. The present study was concluded that melanin pigment obtained from marine actinobacterium of Streptomyces species has potential antioxidant activities and these components might be useful to pharmaceutical industries.
The effectiveness of forest honey toward symptoms of atrophy patients
Authors: Sofyan Asrawati , Nayoan Christin R. , Asrinawaty Andi Nur
Published: May 2024

The effectiveness of forest honey in Total Nasal Symptom Score (TNSS) improvement in allergic rhinitis patients and index Scoring Atopic Dermatitis (SCORAD) in Atopic Dermatitis (AD) patients were discovered. It was an experimental study with a pretest–posttest design. A total of 20 people with atopy (15 people with allergic rhinitis and five people with AD) were given forest honey in the morning (1 ml × 10 ml dose) for 8 weeks and 20 atopy patients without forest honey. TNSS and SCORAD index were evaluated before the intervention, week 2, week 4, and after the intervention (week 8). The mean TNSS before treatment was higher in the honey group, namely 7.73, and a significant decrease after 8 weeks of intervention, namely 2.73 with P = 0.000. The nonhoney group showed that there was no significant difference after 8 weeks with P = 0.888. The SCORAD values of the honey and nonhoney groups had significantly different values from week 0 to week 4 (P = 0.003) and week 0 to week 8 (P = 0.003). Forest honey can give as an additional therapy for patients with allergic rhinitis and AD.
Evaluation of quality of life following dental extraction
Authors: Fathima Tahreem , Kumar M. P. Santhosh
Published: May 2024

Among several treatment modalities done in dental clinics, dental extractions are the most frequently carried out treatment. Tooth extraction is indicated in cases such as chronic periodontal disease, abscess, root caries, root stumps, fractured teeth, and failed root canal treatments with the persistence of periapical cysts or granulomas, impacted teeth, or to facilitate orthodontic or prosthodontic rehabilitation. The consequence of routine tooth extraction could lead to dentoalveolar diseases, which cause tooth loss. The various complications of surgical procedures are delayed wound healing, postoperative bleeding, remnant bony spicules, and nerve paresthesia. This study aimed to assess the impact of nonsurgical tooth extraction on the quality of life of patients. Institutional patient data from January 2021 to April 2021 were analyzed, in which 2000 patients who had undergone extractions at our dental institution were included in our study. The data evaluating the patients' quality-of-life postextraction were recorded. It included speech variation, social interaction, postoperative pain, sleep impairment, and inability to work. Data obtained were statistically analyzed using SPSS, and results were obtained. Most men (49%) experienced an inability to work compared to women (25%). 38% of females had moderate-to-severe pain, whereas males (21%) had only mild pain. 21% of males are isolated socially due to feeling sick, whereas 20% of females are isolated socially due to pain. Speech was affected more postextraction. Most of the patients could not go to work for 1–3 days following the removal of the tooth. Most of the patients were pleased with the procedure, with their symptoms disappearing after the procedure, and were not worried about dental extractions.
Evaluation of difficulty index of impacted mandibular third molar extractions
Authors: Jeyashree T. , Kumar M. P. Santhosh
Published: May 2024

When compared to other teeth, third molars have a greater rate of impaction. Third molars that have been impacted are commonly encountered in dental practice, and it is the reason for complications in third molar surgery. The most commonly performed surgical procedure by dental practitioners is the third molar extraction. Despite a well-planned surgical approach, there are complications in lower third molar extractions. This study analyzes the expected difficulty during surgical removal of lower third molars that are impacted. This study analyzes the expected difficulty during the removal of impacted lower third molars by surgery. With the data from our dental institution database, the difficulty index by Pederson was used to evaluate the difficulty level of the extraction. Using SPSS, data were analyzed and results were obtained. Among impacted left mandibular third molars (38), minimal difficulty in 20.60% of the extractions, moderate difficulty in 29.58% of the extractions, and most difficulty in 2.77% of extractions were present. Among impacted right mandibular third molars (48), minimal difficulty in 18.80% of the extractions, moderate difficulty in 25.78% of the extractions, and most difficulty in 2.47% of extractions were present. According to our study, there is moderate difficulty in impacted lower third molar surgery, and it depends on factors such as systemic status and patient's age, periodontal condition, and complexity of tooth position in the dental arch.
Effect of pit-and-fissure sealants on postbrushing simulation – A photogenic study
Authors: Kishen Akansha , Veeraraghavan Vishnu Priya , Somasundram Jayalakshmi , Gayathri R. , Kavitha S.
Published: May 2024

Pit-and-fissure sealants of the occlusal surfaces for the posterior teeth are well susceptible to develop dental caries compared to the smooth surfaces due to its complex morphology, which makes dental hygiene a challenging fact which give rise to increased plaque accumulation. The use of pit-and-fissure sealants is to provide inhibition toward microorganisms and aggregation of food particles, thereby inhibiting caries initiating and preventing caries progression. The study aimed to assess the effect of pit-and-fissure sealants postbrushing simulation through photography. For this photogenic original study, eight teeth were selected, with two groups each and four teeth present in each of the groups. Brushing simulator machines are well-established methods for analyzing the efficacy of toothbrushes. A total of 10,000 cycles were accounted for by the machine with linear X-axis and Y-axis = 2500 in each group. The clockwise and counterclockwise = 2500 in each group. From the research, it can be concluded that Group A is found to be more effective than Group B, where Group A is Clinpro sealant and Group B is YuSeal. This pit-and-fissure sealant application is very important in clinical practice to prevent the tooth from getting decayed. This research helps us to establish the amount of reduction in both the groups of sealants postbrushing as various brushing patterns influence the retention of pit-and-fissure sealants.
Antimutagenic activity of nanoparticles of Rhaphidophora pinnata leaves in mice using micronucleus assay
Authors: Masfria Masfria , Marianne Marianne , Permata Yade Metri , Octavio Steven , Mulyani Sri
Published: May 2024

Cancer is one of the deadliest diseases in the world. Cancer may occur due to gene mutation. Rhaphidophora pinnata is a plant that has many benefits, especially in the leaves which have been used traditionally to treat cancer. The aim of this research is to test the antimutagenic activity of nanoparticles R. pinnata using the micronucleus method. The mice were induced with cyclophosphamide and then followed with the administration of nanoparticles of R. pinnata at the doses of 50, 100, 200 mg/kg for 7 days. The antimutagenic activity was evaluated at the decrease in the number of micronucleus in 200 polychromatic erythrocytes (PCE) cells of mice bone marrow. The result showed that the reduction of amount of micronucleus in PCE of a negative control group, treatment groups, and normal group is 22.65%, 60.3%, 79.6%, 93.8%, and 100%. These results indicate that the antimutagenic activity of nanoparticle of R. pinnata increases proportionally as the doses were increased. It can be concluded that nanoparticles R. pinnata at the doses of 50, 100, and 200 mg/kg have antimutagenic activity.
Prevalence of pain following single-visit pulpectomy with stainless steel crown done by postgraduate students in a university sitting
Authors: Kumar Ashwin Shravan , Ramakrishnan Mahesh
Published: May 2024

Pain is usually a very unpleasant experience, it can be felt by any age group whose sensory and cognitive components have been developed. Children tend to experience pain in around 65% of dental procedures. It can affect daily activities, and in many situations, it can lead to crisis. Since it is a developing child, the concept of pain can influence adversely in the mind of the child. The clinical records of all pulpectomy cases during the period between January 1, 2020, and January 1, 2021, were analyzed. Gender and age of the patients were also included in the study. The majority of children in our study group were males; children who had a proper abscess of any kind of symptoms tend to have a higher incidence of postoperative pain compared to children with the least symptoms. The study identified that children experienced less pain following multi-visit pulpectomy when compared with single visits during the 1st 3 days. In children who were treated with both single-visit pulpectomy and stainless steel crown experienced no difference in pain perception in the first 3 days of appointment.
Cytotoxicity and antiproliferative activity of ethanol and ethyl acetate fractions from polymeric nanoparticles of green tea leaves (Camellia sinensis) in breast cancer cell line MDA-MB-132
Authors: Kusmiyati Mimin , Rusdin Agus , Trinovani Elvi , Prawira-Atmaja M. Iqbal , Purkon Dicki Bakhtiar , Mulyo Gurid Pramintarto Eko
Published: May 2024

Green tea (Camellia sinensis) has benefits. Its main potential content is epigallocatechin gallate, which has many bioactivity and pharmacological properties. However, herbal medicines have limitations on low solubility and stability. A nanoparticle delivery system is a perfect form of active ingredient development, because it can mediate the increase in solubility, dissolution rate, and strength of a targeted delivery system. This study aimed to make and test the formulation of the ethanol and ethyl acetate fraction from green tea leaves in the form of a nanoparticle delivery system using chitosan biopolymer as the primary carrier polymer combined with sodium tripolyphosphate as a crosslinker and then carried out the tests on the MDA-MB-231 breast cancer cell line. The results showed that the particle size value was 199.7 nm, the zeta potential was-56.7 mV, and the polydispersity index was 0.337. X-ray diffraction and differential scanning calorimetry test results showed that the C. sinensis fraction was perfectly dispersed molecularly in the nanoparticle system. The results of the cytotoxic test on the MDA-MB-231 breast cancer cell line obtained IC50 values for both fractions, namely 10.70 μg/mL (nano ethanol fraction) and 12.72 μg/mL (nano ethyl acetate fraction). This result showed a significant increase in anticancer activity in both fractions compared to those not formulated (P < 0.05). These results also show that the C. sinensis tea fraction formulated in a nanoparticle delivery system has a great potential as a new therapeutic agent for breast cancer.
Anabasis articulata exerts an anti-arthritic effect on adjuvant-induced arthritis in rats
Authors: Abdulhusain Zaid Hamzah , Mahdi Makarim A. , Abdulsahib Waleed K. , Jasim Layth S.
Published: May 2024

Anabasis articulata (AA) is commonly found in the Iraqi desert and is utilized in traditional medicine to cure kidney infections, eczema, fever, and diabetes. The paper aimed to identify the anti-arthritic impact of AA on arthritis models in rats. Complete Freund's Adjuvant (CFA) was used intradermally (ID) for the induction of arthritis. The author classified animals into four groups randomly: The first group took normal saline (control), the second group received AA orally for 14 days before induction and continue 17 days after induction, the third group was induced by CFA and received normal saline orally (model group), and the fourth group took AA orally 17 days after induction. AA administration increased body weight (BW) but decreased arthritis index (AI), histopathological scores, and vascular endothelial growth factor expression in synovial cells. AA has an important antiangiogenesis and anti-arthritic activity in arthritis model rats.
Does age determine the lightness and darkness of tooth shades? A retrospective study
Authors: Bhaskaran Revathi , Sharma Subash
Published: May 2024

The study aimed to analyze whether age determines the lightness and darkness of tooth shades. The demand for esthetics has soared to a next level progressively in many developing countries including India; the importance provided to match the tooth shade creates a great difference in the satisfactory outcome of the patient in the field of dentistry. Therefore, this particular study analyzed the differences in tooth shade values based on age factor among the Indian population. 238 individual's case sheets with the age between 18 and 65 years. 18–30 years of age were considered as group 1 (young adults), 31–45 years in group 2 (middle age), and above 45 years in group 3 (older age). The clinical intraoral pictures of the patients which were taken prior to the treatment were obtained and the shade of any one of the upper permanent central incisors was assessed using the Vitapan 3D-Master shade guide, especially the middle portion of the facial surface of the incisors. The collected data were imported to Statistical Package for the Social Sciences, version 17 (IBM Corporation). Chi-square test was used to assess the significance. From the data, 17.2% showed A1 shade, 35.2% A2 shade, 7.5% A3 shade, 5% A4 shade, 7.1% B1 shade, 15.9% B2 shade, 7.1% B3 shade, 3.3% B4 shade, and 1.1% C1 shade. The individuals under the category of above 45 years showed darker tooth shade compared to young adults and middle age population (Chi-square test, P < 0.001). Significant association was established with darker tooth shades by increasing age and vice versa. The older age population showed a higher correlation for dark shade between teeth. The aging process significantly affects the teeth color. Hence, as a dentist, it is important to know about the distribution of tooth shade and its association with age to get an outcome with adequate patient satisfaction.
Colposcopy and Smoking Cessation: Survey and Education Intervention Pilot Study
Authors: Elangainesan Praniya , Simard-Émond Laurence , Zigras Tiffany , Willows Karla , Selk Amanda
Published: May 2024

Objective:

The objective of the study was to understand variations in smoking cessation practices across Canadian colposcopy clinics and to assess improvements in smoking cessation counseing after the provision of jurisdiction-specific resources.

Methods:

An electronic survey was sent to members of the Society of Canadian Colposcopists and the Gynaecologic Oncologists of Canada to characterize current smoking cessation counseling practices to inform the design of the educational initiative. Colposcopy clinics were invited to participate in the pilot involving the collection of smoking counseling data from patient charts pre- and postintervention. Region-specific smoking cessation resource toolkits were created for participating clinics. Descriptive statistics were used for the analysis.

Results:

32/266 colposcopists responded to the survey. 25/32 respondents indicated that they asked all patients about their smoking status. Most respondents indicated that they tell patients smoking increases the risk of developing cervix cancer (88%) and that smoking negatively affects the immune system and human papillomavirus clearance (94%). Five clinics participated in the education initiative. While there is variation in practice, after providing smoking cessation resources to clinics, both assessing smoking status and smoking cessation counseling improved with most sites increasing their referral rates to family doctors or smoking cessation clinics (range: 10%–50%).

Conclusions:

Gaps exist in smoking cessation counseling in some Canadian colposcopy clinics. Standardizing assessment and documentation of smoking status, using effective models of counseling, and providing jurisdiction-specific resources to colposcopy clinics may improve smoking cessation counseling.
Wide Local Excision versus Simple Vulvectomy in Vulval Intraepithelial Neoplasia 3: Case Report and Literature Review
Authors: Singh Nilanchali , Ramu Sivalakshmi , Rathore Ruchi , Sehra Divya , Meena Jyoti
Published: May 2024

Vulvar intraepithelial neoplasia is a premalignant lesion of the vulva. Women with vulvar cervical intraepithelial neoplasia 3 are at high risk of recurrence and vulvar carcinoma. They warrant a surgical management for the same reason. It may be either ablative or excisional, sometimes can be a combination of both. The decision for wide local excision or simple vulvectomy depends on clinical factors. Case: We present a case of a 67-year-old lady who presented with vulvar itching and a large black vulvar lesion involving the fourchette area, with HPV 16 positive. Initially, there was a doubt of melanoma, but vulval biopsy was suggestive of high-grade squamous intraepithelial lesion (HSIL) (vulval intraepithelial neoplasia 3 [VIN 3]). As it was a single large lesion, the initial plan was wide local excision but as the lesion was large and occupying almost half of the vulva, the decision of simple vulvectomy was taken. A wide local excision would have resulted in vulvar asymmetry and since there was a big lesion, chances of satellite lesions over the vulva were there; decision was made for simple vulvectomy. In this case report, we will review the literature on the surgical management of VIN 3. Conclusion: Treatment is recommended for all vulvar HSIL because of the potential for invasion. Simple vulvectomy is an easy procedure, with less hospital stay, less blood loss, and least recurrence rates. It is a suitable treatment option for multifocal and large lesions of the vulva.
Vulval Fibroid: A Rare Presentation
Authors: Mishra Archana , Gupta Chhavi , Shamsunder Saritha , Ahuja Sana , Malik Shaivy
Published: May 2024

This case study presents a rare occurrence of vulval leiomyoma in a reproductive-aged female, initially misdiagnosed as Bartholin’s cyst. Vulval leiomyomas, although uncommon, present significant diagnostic challenges due to their nonspecific clinical features. Histopathological examination remains crucial for definitive diagnosis, with characteristic microscopic features including whorls of spindled smooth muscle cells. Differential diagnosis from other vulval lesions, particularly Bartholin’s cyst, is essential for appropriate management planning. Imaging modalities such as transperineal ultrasound and magnetic resonance imaging may aid in preoperative differentiation. Surgical excision with clear margins is the mainstay of treatment, although leiomyosarcomas may require more aggressive interventions. This case underscores the importance of considering vulval leiomyoma in the differential diagnosis of vulval swellings and highlights the need for a multidisciplinary approach to ensure accurate diagnosis and optimal management.
Value of the three-dimensional visualization ablation planning system in ultrasound-guided percutaneous microwave ablation for malignant adrenal tumors: A clinical comparative study
Authors: Du Qiaowei , Li Xin , Lin Zheng , Dong Linan , Liu Fangyi , Liang Ping
Published: May 2024

Objective:

We aimed to assess the efficacy and safety of the three-dimensional visualization ablation planning system (3DVAPS) in ultrasound-guided percutaneous microwave ablation (US-PMWA) for malignant adrenal tumors (MATs).

Methods:

A retrospective analysis was conducted on a cohort of 62 unilateral MAT cases from March 2011 to November 2022. There were a total of 62 lesions, with a mean maximum diameter of 5.4 ± 2.7 cm (range, 1.4–15.7 cm). The patients were categorized into the following, based on the pre-operative planning method: 3D planning (n = 32) and 2D planning (n = 30) groups. A comparative analysis was performed on various parameters, including ablation techniques, tumor-related prognosis, and incidence of complications. This analysis encompassed indicators, such as overall survival (OS) rate and local tumor progression (LTP), among others.

Results:

The median follow-up period was 30 months (range, 3–84 months). Notably, compared with the 2D planning group, the 3D planning group exhibited significant disparities in the number of punctures (P = 0.035) and incidence of complications (P = 0.029) and had no significant difference in the OS (P> 0.05) but had a significantly lower LTP rate (6.2% vs. 23.3%,P= 0.033). In the 3D planning group, the sub-group with a tumor diameter of < 5 cm exhibited a significantly less number of punctures (P= 0.039), lower input energy (P= 0.002), and a shorter ablation time (P= 0.001), compared with the sub-group with a tumor diameter of ≥ 5 cm, but there was no significant difference in the LTP and OS rates between the two sub-groups (P> 0.05).

Conclusions:

The use of 3DVAPS in US-PMWA of MATs was advantageous, especially in lesions with a diameter of ≥ 5 cm. It can help in developing more rational surgical plans, reducing the incidence of complications, and extending the local recurrence-free survival time of patients and can add a certain value for precise treatment and expand the indications for ablation.
Novel alternative use of surgical guides in full-mouth implant rehabilitation cases
Authors: Thumati Roshan P , Thumati Prafulla , Comandur Srikar
Published: May 2024

Surgical guides (SGs) have been commonly used in full-mouth rehabilitation and numerous advances have been adopted in their development. However, they have been restricted to implant placement and are later rendered useless. They further add to the burden of biological waste management following their limited use. The quantum of technologies and materials used to make us ponder if they can be used further. This article establishes different ways of using SG in different stages of prosthetic phase of treatment by demonstrating the procedures clinically. It gives us an insight into how the guides can be used for implant localization and exposure during the secondary surgical phase and also during impression making, thereby enhancing the treatment outcome.
Comparative evaluation of bone density changes around root-form, threaded collar, two-piece endosseous implants at three different levels as influenced by early loading and conventional loading protocols using cone-beam computed tomography
Authors: Khan Shuja Mohammed , Kumar Manoj , Issar Gaurav , Dhillon Manu , Poduval T Soorya , Tyagi Shweta
Published: May 2024

Background:

Understanding the changes in bone density after insertion of dental implants and their relation to immediate/early loading is essential to achieving improvements in their survival rate. Histological investigations of the bone bed in humans are limited, which in turn hampers opportunities to deepen knowledge about the remodeling process around dental implants.

Purpose:

The aim of this pilot study was to comparatively evaluate the bone density changes around root-form, threaded collar, two-piece endosseous implants at three different levels as influenced by early and conventional protocols using cone-beam computed tomography (CBCT).

Methodology:

Twenty implants were placed in 20 patients who were randomly assigned to two groups. Group A (n = 10 implants, 10 patients) received conventional loading protocol and Group B (n = 10 implants, 10 patients) followed early loading protocol following implant placement. Bone density changes were evaluated and compared as influenced by early and conventional protocols using CBCT (gray values). The gray values were measured at the apical level, middle region of radiological implant length, and at the crestal level. The measurements were made immediately (T0) and 36 weeks (T1) post implant placement.

Results:

Intergroup comparison of bone density changes was done between Group A (conventional loading) and Group B (early loading) from immediate post implant placement to 36 weeks post implant placement follow-up. From immediate post implant placement to follow-up, significant difference was seen in bone density of Group A and Group B at apical and middle levels as P < 0.05, but at crestal level, no significant difference was seen.

Conclusion:

Under the conditions of this study, early loading significantly densified more bone as compared to conventional loading. Further studies are required to determine CBCT gray values and its correlation with computed tomography Hounsfield units for quantification of the bone.
All-on-four treatment with narrow platform implants in reduced restorative space for moderate atrophic edentulous ridge
Authors: Durrani Farhan , Pandey Aishwarya , Singh Preeti , Pandey Samidha , Nahid Rakhshinda
Published: May 2024

The use of dental implants to treat edentulous maxilla and mandible is a well-accepted concept in modern dentistry. However, it is difficult and challenging in atrophic jaws. All-on-four implant concept is an alternative for resorbed jaws, as it obviates extensive bone grafting and waiting time and often provides immediate function. In our article, we describe the use of narrow platform implants (3.3 mm) for a moderate atrophic complete edentulous case with the above concept. The studies with narrow-diameter implants for complete reconstruction are inadequately reported. We followed our case for 3 years after the delivery of final prosthesis.
Probiotics lessens pathological changes in rabbits infected with hepatic coccidiosis
Authors: Jameel Maab Salah , Kalef Dalia Ahmed
Published: May 2024

Objective:

This study aimed to evaluate the efficacy of probiotics in the treatment of hepatic coccidiosis in rabbits.

Methods:

A total of 30 White New Zealand rabbits of both sexes, aged 4-6 weeks and weighing 600-700 g, were divided into three groups. The first group of rabbits received probiotics (100 mg/L) in drinking water for 12 days, while the second group of rabbits served as a positive control. Both groups were challenged with 1 × 105
Eimeria stiedae oocysts. The third group of uninfected rabbits served as the negative control. The effects of probiotic treatment on fecal oocysts output, body growth gain, liver enzymes, red blood cell count, hemoglobin level, packed cell volume, lymphocytes count and histopathological lesions were observed.

Results:

Compared to the positive control, rabbits treated with probiotics exhibited no diarrhea or mortality, and there was a significant reduction in fecal oocysts output. Additionally, body growth gain was significantly higher in probiotic-treated rabbits compared to the positive control. Furthermore, liver enzymes and white blood cell counts were decreased in treated rabbits, while red blood cells, hemoglobin, packed cell volume and lymphocyte count were elevated. Severe histopathological lesions were observed in the bile ducts and hepatic parenchyma of positive control rabbits compared to probiotic-treated and negative control groups. The study findings were statistically significant, with P values ranging from less than 0.001 to less than 0.05.

Conclusions:

Probiotics significantly improve the health performance of rabbits with hepatic coccidiosis by reducing pathological changes and stabilizing hematological parameters. Additionally, this product maintains substantial normal liver enzymes levels in infected rabbits, making it a safe and effective treatment for hepatic coccidiosis in rabbits.
Assessment of hygiene practices at the human-animal interface: A One Health perspective
Authors: Tadvi Ravina , Yasobant Sandul , Patel Krupali , Saxena Deepak
Published: May 2024

Objective:

This mixed-methods study aims to develop and validate a comprehensive hygiene tool from a One Health perspective to document the assessment of hygiene at the human-animal interface.

Methods:

This mixed-methods study consisted of two components: a narrative review of the development of tool, followed by validation. The tool development was conducted in two phases. Phase 1 was a literature review, while phase 2 focused on the development and validation.

Results:

Tool version 1 consisted of 37 questions to assess personal hygiene practices among 16 households with livestock. Face validity, content validity, and multi-rater kappa scores were used to validate tool version 1. The questions with kappa score exceeding 0.74 were retained for further test. A total of 29 questions were obtained and incorporated into tool version 2, which was subsequently employed to evaluate the personal hygiene practices among 62 households with stock. The median total scores for 16 households and 62 households were 10.5 (range: 6-16) and 16 (range: 10-22), respectively.

Conclusions:

Many studies have assessed hygiene practices among livestock farmers, yet none used a validated assessment tool. Thus, this validated tool will facilitate the measurement of hygiene in human-animal interactions.
Proximate Composition, Microbial, and Sensory Assessment of Smoked Clarias gariepinus Packaged in Retort Pouch
Authors: Ricketts Amighty , Onoja Sophia , Blessing Uke , Idoko David
Published: May 2024

This study analyzed the effect of retort processing on smoke-dried fish. Fresh Clarias gariepinus were smoked and divided into two groups – retort prosessed samples (RPS) and unretorted samples (URS). Samples were kept in normal room conditions. Significant differences were observed in the proximate compositions and microbial loads over time. The moisture content was higher in RPS (8.53% to 8.84%) compared to URS, with significant differences emerging from day 14. Protein content showed notable changes, with URS recording a high of 70.00±0.00% on day 14 and RPS dropping to the lowest at 65.28±0.40% by day 56. Lipid levels were highest in RPS, peaking at 15.43±0.10, and ash content was lower in RPS (4.39±0.02 on Day 28) compared to URS. Microbial analysis indicated a decrease in total viable count in RPS from the first day, whereas it increased in URS throughout the 56 days. Sensory evaluations showed no significant differences in RPS over time, maintaining high ratings in all categories while URS experienced a decline in sensory qualities, notably with flavour and general acceptability. These findings demonstrate the effectiveness of retort processing in maintaining quality under extended storage.
Regulation Mechanism of miR-23a in Oreochromis mossambicus During Aeromonas hydrophila Infection
Authors: Ya Shiya , Gan Hui , Lv Min , Luo Xu , Pan Chuanyan , Zhang Wenmin , Ma Huawei , Ruan Zhide
Published: May 2024

This study used Aeromonas hydrophila infection and culture of tilapia (Oreochromis mossambicus) renal cells to analyze the time dependent expression of miR-23a in tilapia renal cells infected with A. hydrophila. The current results showed that the expression of miR-23a changed significantly at different time points of infection. Using RNAhybrid software to predict the target site of miR-23a and construct a plasmid, the binding ability of the target gene 3`-UTR to miR-23a was verified through dual luciferase reporter gene assay. We found that target genes were reverse regulated, and tbk1, glut1 were identified as miR-23a target genes. Expression of ldha, ldhba, pdha 1a and pdha 1b was suppressed after overexpression of miR-23a. These results indicated that miR-23a was involved in the regulation of the immune response in tilapia kidney cells after A. hydrophila infection. tbk1 and glut1 are the target genes of miR-23a that can affect the expression of downstream genes by targeting GLUT1. The above results provide important insights into the role of miR-23a in regulating the immune response in bony fish and further understanding of miRNA-mediated multiple target genes to regulate innate immunity in fish.
Genetic Structure of the Antoniny-Zozulenets Intrabreed Type of Ukrainian Leather and Scaly Carps Using Microsatellite Markers
Authors: Mariutsa Alla , Borysenko Nataliia , Bielikova Olena , Kurinenko Hanna , Oborskiy Viktor , Dyman Tetyana
Published: May 2024

The common carp (Cyprinus carpio) is a dominant aquaculture species in Ukraine with several intra-breed types within two recognized breeds: scaly and leather. Understanding their genetic diversity is crucial for successful breeding programs. This study is focused on a genetic characterization of Antoniny-Zozulenets intrabreed type of scaly and leather carps from the Stara Synyava fish hatchery, which were produced by selective breeding in Ukraine. Microsatellite analysis was conducted using six DNA loci: MFW 02, MFW 06, MFW 09, MFW 15, MFW 23, MFW 31; all of which were polymorphic in both groups. The mean polymorphic information content was 0.903±0.009. The ranges of amplicons for the selected loci were determined. This enabled the characterization of specific genetic features of each breed. Allelic richness ranged from 9.987 to 14.512 for scaly carp and 9 to 13 for leather carp. Notably, loci MFW 02, MFW 09, MFW 23 in the scaly carp group exhibited a wider range and number of alleles compared to leather carp. The Shannon diversity index averaged 2.481±0.060 for scaly carp and 2.348±0.056 for leather carp. The fixation index had negative values, indicating a predominance of heterozygous genotypes (scaly: F=-0.025; leather: F=-0.072). The efficiency of the proposed set of markers was confirmed. These markers could be further used in monitoring genetic diversity and differentiation of carps in Ukraine for breeding and conservation efforts.
VIRADA RITUAL E A ÉTICA DA ALTERIDADE EM BYUNG-CHUL HAN: A REINSERÇÃO DA ARTE DA ATENÇÃO, DA ESCUTA E DO OLHAR NA VIDA EM COMUNIDADE
Authors: Camila Braga Soares Pinto  , Leandro Pinheiro Chevitarese
Published: May 2024

Os rituais são ações simbólicas. Eles transmitem e representam valores e ordens que mantêm uma comunidade unida. São “técnicas de fechamento temporal”, visando permanência e vínculo e apresentam eixos de estabilização para a vida. Este trabalho discutirá possibilidades de reinserção desta prática coletiva no âmbito de uma Sociedade do Desempenho. Tal configuração societária tem se apresentado de maneira embrutecida, atomizada e de moral amorfa, em um cenário em que se caracteriza o inferno do igual a partir da expulsão da alteridade. A partir da matriz de pensamento de Byung-Chul Han, propõe-se, portanto, um chamamento para uma virada ritual de modo a se oferecer “mimetizações possíveis à felicidade” e intermediar uma “referência ao mundo”. Além disso, recuperar-se os ritos, valoriza o desfrute de um tempo cadenciado e contemplativo, um tempo do outro e do sorver das coisas. Mais ainda, ressignifica a potência de suas formas próprias para permitir a sensibilidade, o acolhimento de si e também da recuperação da alteridade, que prima pela diferença em um viver comunal. Estas experiências de conclusão, permeiam um tipo de ética que nos elabora de forma atópica e não simplesmente autêntica no encontro com o inteiramente outro, que é “constitutivo para a formação de um si estável”. Promove-se um caminho ético propositivo, através de um retorno à arte da escuta, da atenção profunda, da cortesia do gesto inerentes à qualidade do olhar e à corporeidade da voz.
CHILDREN’S FICTION AS AN IDEOLOGICAL STATE APPARATUS: ANALYZING SELECTED BRITISH SHORT STORIES FOR CHILDREN AS WORKS OF COLONIAL LITERATURE
Authors: Anwaar Tayyaba Fatima , Dr Amara Khan
Published: May 2024

Building upon select short stories by Enid Blyton and Rudyard Kipling, this research aims to explore propagation of the imperialist ideology through British short stories for children. The select stories are examined as part of the discourse developed to glorify Britain and depreciate its colonized subjects. The study discusses the stories as they explore colonization in light of the theories developed in the Metropole. Keeping in view that children’s fiction promotes various ideologies, this research argues that short stories for children may become an immensely significant medium in fostering the imperialist ideology, thus functioning as Ideological State Apparatuses through the very important learning years of childhood. For this purpose, the theoretical framework of Ideological State Apparatuses by Louis Pierre Althusser has been employed. This incorporation serves to elucidate the role of educational ISAs in shaping the minds of children from early childhood. Children’s indoctrination in such manner may produce new generations of people that might support the colonialist stance both knowingly or unknowingly. A useful strategy to counter this situation is writing back to the Empire by producing children’s books that function as sights of decolonization. The real challenge, however, is to make de-colonial literature accessible to young minds around the globe.
PENERAPAN METODE EKSPERIMEN HUJAN UNTUK MENGEMBANGKAN SAINS PADA ANAK USIA DINI DI TK A AISYIYAH BUSTANULATHFAL V KOTA PROBOLINGGO
Authors: Siti Fatimah  , Dirgayunita Aries
Published: May 2024

Abstract
Science is the investigation of science with various activities of natural phenomena. The experimental method is to invite children to recognize various things for how the rain process occurs and how to develop their science, information or data through observation of the experimental process. The problem in this study is to determine the ability of science through experimental activities at ABA V Kindergarten. This research uses PTK with a qualitative descriptive approach. Consists of 3 cycles including pre-cycle, cycle 1, and cycle 2 and each cycle is carried out for 2 meetings. This study shows that the results of pre-cycle child assessment observations with a percentage of 25%, and in cycle 1 the ability of children is a percentage of 50%, with the BSH category), in cycle II a percentage of 75% is in the category (BSB). That the result of this rain experiment method, is that the ability and development of children towards science is increasing.
Keywords: early childhood, experimental methods, developing science.
Analisis Kelayakan Investasi Pembangkit Listrik Tenaga Surya Atap Dengan Sistem Off-Grid Pada Indekos Di Kota Surabaya
Authors: Sechan Maulana , Valubia Ramadhan Dava , Mas Soeroto Wisudanto
Published: May 2024

PLTS atap off-grid menjadi salah satu alternatif peralihan dari sumber energi berbahan dasar fosil menjadi sumber energi terbarukan, yaitu menggunakan sinar matahari. Hal ini sejalan dengan persoalan pemenuhan kebutuhan energi di Indonesia yang masih menggunakan energi berbasis fosil berupa minyak bumi, gas bumi, dan batu bara. Tujuan dari penelitian ini adalah untuk menganalisa kelayakan investasi PLTS atap off-grid pada sebuah indekos di Kota Surabaya, dengan metode perhitungan Discounted Payback Period (DPP), Net Present Value (NPV), Internal Rate of Return (IRR), dan Profitability Index (PI). Metode yang digunakan berupa studi literasi dari penelitian yang sudah dilakukan sebelumnya dan simulasi keluaran energi dari PLTS atap off-grid yang dihasilkan melalui software analisis simulasi PVSyst untuk menghitung nilai DPP, NPV, IRR, dan PI sebagai dasar untuk menentukan kelayakan investasi PLTS atap off-grid pada indekos di Kota Surabaya.  Hasil penelitian menunjukkan bahwa investasi PLTS atap off grid pada sebuah indekos di Kota surabaya dengan menggunakan metode perhitungan DPP, NPV, IRR, dan PI dalam kategori layak untuk dilaksanakan Kesimpulan menunjukan pemasangan sistem PLTS ini merupakan pilihan yang baik untuk meningkatkan efisiensi energi dan mengurangi biaya operasional pada indekos di Kota Surabaya.
Strategi Komunikasi Disperindagkop Ukm Provinsi Kalimantan Timur Kepada Pelaku Umkm Kota Samarinda Dalam Pelaksanaan Pembayaran Digital
Authors: Ri’fat Andi , Apriani Fajar
Published: May 2024

Penelitian ini dilakukan dengan tujuan untuk mengetahui strategi komunikasi Disperindagkop UKM Provinsi Kalimantan Timur kepada pelaku UMKM Kota Samarinda dalam pelaksanaan pembayaran digital yang merupakan bentuk transformasi digital dalam kegiatan ekonomi saat ini, yang dikenal dengan Quick Response Code Indonesian Standard atau QRIS. Dengan menggunakan metode deskriptif kualitatif, strategi komunikasi Disperindagkop UKM Provinsi Kalimantan Timur dianalisis berdasarkan aspek pengenalan khalayak, penyusunan pesan, penetapan metode pelaksanaan, seleksi dan penggunaan media serta faktor penghambatnya. Teknik pengumpulan data dilakukan melalui observasi, wawancara, dan dokumentasi. Melalui analisis data dengan mempergunakan model interaktif, hasil penelitian menunjukkan bahwa strategi komunikasi Disperindagkop UKM Provinsi Kalimantan Timur kepada pelaku UMKM Kota Samarinda dalam pelaksanaan pembayaran digital sudah terlaksana namun belum maksimal. Hal ini disebabkan masih adanya sebagian pelaku UMKM yang belum mendapatkan sosialisasi pelaksanaan pembayaran digital dan belum mengadopsi penggunaan pembayaran digital QRIS, khususnya di Kota Samarinda. Pelaksanaan strategi komunikasi Disperindagkop UKM Provinsi Kalimantan Timur kepada pelaku UMKM Kota Samarinda dalam pelaksanaan pembayaran digital juga masih terhambat oleh terbatasnya sumberdaya yang dimiliki Disperindagkop, keterbatasan infrastruktur teknologi, kurangnya pemahaman pelaku UMKM tentang literasi digital hingga tidak mau mengikuti program pelaksanaan pembayaran digital yang telah disosialisasikan Disperindagkop, serta faktor konsumen yang sebagian besar masih menggunakan pembayaran secara tunai dalam bertransaksi.