bluuebunny/crossref_metadata_2025 huggingface dataset:
QARTA
Authors: Musleh Mashaal , Abbar Sofiane , Stanojevic Rade , Mokbel Mohamed
Published: October 2021

Maps services are ubiquitous in widely used applications including navigation systems, ride sharing, and items/food delivery. Though there are plenty of efforts to support such services through designing more efficient algorithms, we believe that efficiency is no longer a bottleneck to these services. Instead, it is the accuracy of the underlying road network and query result. This paper presents QARTA; an open-source full-fledged system for highly accurate and scalable map services. QARTA employs machine learning techniques to construct its own highly accurate map, not only in terms of map topology but more importantly, in terms of edge weights. QARTA also employs machine learning techniques to calibrate its query answers based on contextual information, including transportation modality, location, and time of day/week. QARTA is currently deployed in all Taxis and the third largest food delivery company in the State of Qatar, replacing the commercial map service that was in use, and responding in real-time to hundreds of thousands of daily API calls. Experimental evaluation of QARTA shows its comparable or higher accuracy than commercial services.
Synthesis of novel thiourea-/urea-benzimidazole derivatives as anticancer agents
Authors: Siddig Lamia A. , Khasawneh Mohammad A. , Samadi Abdelouahid , Saadeh Haythem , Abutaha Nael , Wadaan Mohammad Ahmed
Published: October 2021

A new series of urea and thiourea derivatives containing benzimidazole group as potential anticancer agents have been designed and synthesized. The structures of the synthesized compounds were characterized and confirmed by spectroscopic techniques such as 1H NMR, 13C NMR, and mass spectrometry. In vitro anticancer assay against two breast cancer (BC) cell lines, MDA-MB-231ER(−)/PR(−) and MCF-7ER(+)/PR(+), revealed that the cytotoxicity of 1-(2-(1H-benzo[d]imidazol-2-ylamino)ethyl)-3-p-tolylthiourea (7b) and 4-(1H-benzo[d]imidazol-2-yl)-N-(3-chlorophenyl)piperazine-1-carboxamide (5d) were higher in MCF-7 with IC50 values of 25.8 and 48.3 µM, respectively, as compared with MDA-MB-231 cells. Furthermore, 7b and 5d were assessed for their apoptotic potential using 4′,6-diamidino-2-phenylindole, acridine orange/ethidium bromide staining, and Caspase-3/7. After incubation with MCF-7, the compounds 7b and 5d induced apoptosis through caspase-3/7 activation. In conclusion, the compounds 7b and 5d are potential candidates for inducing apoptosis in different genotypic BC cell lines.
¿El bienestar subjetivo contribuye a nuestra comprehensión del bienestar mexicano?
Authors: Heald Jeremy , Treviño Aguilar Erick
Published: October 2021

El artículo hace una reseña de la literatura del bienestar y mide cómo los cuestionarios con preguntas subjetivas pueden mejorar nuestra comprensión del bienestar en México. El cuestionario utiliza datos a nivel estatal principalmente de dos cuestionarios de enfoque subjetivo, Módulo de Bienestar Autorreportado (BIARE) y Encuesta Nacional de Victimización y Percepción sobre Seguridad Pública (ENVIPE), ambos aplicados en 2014. El estudio emplea un análisis descriptivo y econométrico de indicadores inspirado tanto en la teoría como en investigaciones mexicanas previas. El análisis confirma que el bienestar subjetivo correlaciona con y complementa los datos objetivos y que la felicidad crece con un aumento en los ingresos, como lo sugiere la teoría. Además, se encontró que los mexicanos son relativamente felices, considerando los bajos ingresos y los altos niveles de inseguridad en el país. Se sugiere que el bienestar es un fenómeno complejo y multidimensional que se puede explorar utilizando la regresión múltiple exploratoria y modelos de correlación parcial que yuxtaponen indicadores subjetivos y objetivos.
Foam Rolling on Uric Acid Levels Profile in Delayed Onset Muscle Soreness (DOMS) post 10 Km Long-Distance Running in Healthy Trained Young Men
Authors: Ali Mohammad Arif , Sadhali Muchamad , Rahayu Setya , Anggita Gustiana Mega , Kurniawati Dewi Marfu'ah , Mohamed Ani Mazlina Dewi
Published: October 2021

Long distance running (LDR) is an exercise that has a relatively heavy load which can cause Delayed Onset Muscle Soreness (DOMS) and increase Reactive Oxygen Species (ROS) levels. Xanthine, one derivate of ROS will increase 10 times during aerobic activity which is metabolized to Uric Acid (mg/dL) (UA). Foam rolling (FR) is used for the recovery process. This study aims to determine the effect of long distance running on changes in UA levels and the effect of FR as an active recovery against changes in UA levels. This was a quasi-experiment study using a purposive sampling design, one-group repeated measure design of a sample population of young healthy males (17-25 years). The sample consisted of 10 trained young males in Semarang. The average value of UA before intervention was 4.43 mg/dL Â± 0.51. In 90 minutes, it was 5.90 mg/dL Â± 0.52, in 120 minutes was 5.71 mg/dL Â± 0.72 and at 24 hours after intervention was 6.1 mg/dL Â± 0.57. LDR has been shown to increase UA levels. FR which is done only once has not been able to reduce UA levels. The percentage of occurrence of post-LDR DOMS occurred at 24 hours.
Efecto sobre el rendimiento del trigo (Triticum aestivum) de la roya amarilla causada por Puccinia striiformis f. sp. tritici
Authors: Lavilla Miguel
Published: October 2021

Introducción. En los últimos años la roya amarilla causada por Puccinia striiformis fue la enfermedad más prevalente en trigo (Triticum aestivum), en el norte de la provincia de Buenos Aires. Objetivo. Evaluar el progreso de la roya amarilla en cultivares de trigo, con y sin aplicación de fungicida foliar y su efecto sobre el rendimiento y sus componentes. Materiales y métodos. Este estudio se llevó a cabo durante dos años consecutivos (2017 y 2018) en la localidad de Junín, Buenos Aires, Argentina, en diecinueve cultivares de trigo, con y sin aplicación de fungicida foliar. Se cuantificaron los daños de la roya amarilla sobre el rendimiento y la calidad industrial. Se evaluó la evolución de la enfermedad mediante el área bajo la curva de progreso de la intensidad de la enfermedad (ABCPIE). Se asoció el ABCPIE con el rendimiento, sus componentes y el peso hectolítrico. Resultados. De todas las variables analizadas, el ABCPIE tuvo una interacción significativa (p<0,05) entre la aplicación de fungicida foliar y cultivar utilizado. Los cultivares Lapacho, Minerva, MS 415 y SY 211, fueron resistentes a la roya amarilla. El cultivar más susceptible a la enfermedad fue Algarrobo. La aplicación de fungicida foliar, con niveles bajos de la enfermedad, redujo significativamente su evolución; reflejado a partir del área bajo la curva de progreso de la intensidad de la enfermedad. Conclusión. La evolución en el tiempo de la roya amarilla causada por P. striiformis dependió del comportamiento genético del cultivar y de la aplicación de fungicida foliar. Los cultivares que tuvieron los mayores rendimientos, menor ABCPIE y mayor peso hectolítrico fueron: Lapacho, SY 11, BIO 1006 y Minerva.
Applied real-valued genetic algorithm for an extended model of economic lot, purchase and delivery scheduling problem
Authors: Hasheminejad Seyed Ali , Valipour Khadijeh , Khoshnood Hamid
Published: October 2021

Supply chain management intends to integrate supply chains' activities such as material flow, information flow and financial issues. Material flow management is the most significant issue since the inventory level in the whole supply chain could be optimized by an integrated plan. In other words, when one member of the supply chain plans to reduce its inventory level solely, despite reducing inventory in this node the inventory will be stocked in other partners' warehouses. Therefore, in this paper a new mathematical model has been developed to facilitate the process of finding the optimum solution in economic production, purchase and delivery lots and their schedules in a three-echelon supply chain environment; including raw material in suppliers, manufacturer and assembly facility as a customer. The manufacturer with a flow shop system provides its requirements from supplier, assemble multiple products, and delivers products to the customer (automotive OEM alike) on an optimum multiple delivery points. The delivery cycles would be identified through the production common cycle regarding the supply chain flexibility. Finally, a modified real-valued Genetic Algorithm (MRGA), and an Optimal Enumeration Method (OEM) are developed, and some numerical experiments have been done and compared as well.
Inference-embedded yes/no interrogatives in Mandarin Chinese conversation
Authors: Guo Hui , Wu Yaxin
Published: October 2021

In talk-in-interaction, the details of the design of a yes/no interrogative (YNI) index the speaker’s epistemic stance about the issue in question. Adopting conversation analysis as the research method, the present study examines the interactional deployment of inference-embedded YNIs in Mandarin Chinese. The analysis of the turn designs and sequential environments of these interrogatives, as well as the design of the responses to them, indicates that a sequence organisation is engendered in and through the production of inference-embedded YNIs. Since the recipient has epistemic primacy over what is questioned, the questioner’s inference embedded in YNIs may be congruent or incongruent with the recipient’s own state of affairs. In this respect, the questioner’ s inference may be right or wrong. If the recipient finds that the inference is wrong, he or she has the responsibility to execute correction of the questioner’s wrong inference. Indeed, the recipient does display his/her treatment of the inference as wrong through correction. It is through such reflexive connection between the production (action formation) and the interpretation (action ascription) of the YNI that the inference-embedded YNI is treated as a practice for projecting a correction of what is inferred to the question recipient.
Japanese te iu ka as a sentence-final expression in writing
Authors: Nishi Hironori
Published: October 2021

The present study explores cases of the use of the Japanese expression te iu ka in the sentence-final position in internet blogs and discussion boards. The analysis shows that there are two types of sentence-final te iu ka: one used for adding supplementary information and the other for mitigating the preceding statement. The present study also discusses processes through which te iu ka is placed in the sentence-final position. When sentence-final te iu ka is used to add supplementary information, the placement of te iu ka in the sentence-final position is caused by right dislocation. When sentence-final te iu ka is used for mitigation, it is caused by the omission of the B component in A te iu ka B. The present study contributes to the existing literature by offering the notion of two different formation processes of sentence-final te iu ka, which also affect its pragmatic functions.
Condición de salud bucal de una población víctima del conflicto armado del municipio de Girardota, Antioquia
Authors: Gallego Clara Liliana
Published: October 2021

Introducción: La historia del conflicto armado en Colombia ha dejado miles de víctimas y  desplazados que actualmente continúan afrontando graves consecuencias en su calidad de vida, lo que se ve reflejado en su situación de salud y especialmente en su salud bucal.

Objetivo: Describir la condición de salud bucal de la población víctima del conflicto armado del municipio de Girardota – Antioquia.

Materiales y métodos: Se realizó un estudio cuantitativo descriptivo en una muestra de 52 personas. Se realizó una encuesta estructurada y un examen clínico para el índice de placa de Silness y Löe, índice periodontal básico, COP-M, situación y necesidad de prótesis.

Resultados: El promedio de edad de 40,5 años, el 75% eran mujeres, mayormente pertenecientes a los estratos 1 y 2, con un grado de escolaridad de básica primara en el 42%, e ingresos menores a 1 SMMLV en el 60,5%. El índice COP-D fue de 11 y el COPD-M de 13, la prevalencia de caries fue del 80%, presencia de gingivitis en el 56.9%, y periodontitis del 41,2%, el 55,8% presentaron necesidades de prótesis. El 30,8% asistió a consulta en el último año, en un 40% por dolor o caries. El 62% considera regular su estado de salud bucal, y el 87,8% considera necesitar tratamiento odontológico.

Conclusiones: Se encontró una estrecha relación entre las condiciones socioeconómicas y peores condiciones  de salud bucal en la población. Las estrategias de intervención en la población deben estar enfocadas en la rehabilitación oral para suplir sus necesidades
SMU.759 que codifica para una proteasa similar a colagenasa es constitutivo en Streptococcus mutans
Authors: Sáenz Rivera Eduardo de Jesús , Bañol Acevedo Edgar Mauricio , Rincón Rodríguez Ramiro Javier
Published: October 2021

Introducción: En la dentina se encuentra el colágeno tipo I que puede ser degradado por acción enzimática. El gen SMU.759 de Streptococcus mutans, serotipo c, codifica una proteasa con posible actividad colagenasa afectando probablemente este tipo de colágeno y favoreciendo el avance de la caries, dado que, en procesos posteriores a la desmineralización, el colágeno tipo I de la dentina queda expuesto a la acción de esta bacteria. Se pretende determinar si hay diferencias en la presencia o ausencia de SMU.759 en aislados de pacientes con y libres de caries. Métodos: se utilizaron aislados de un cepario procedentes de escolares entre 6 y 9 años de edad con y libres de caries de la ciudad de Medellín, Colombia. Se diseñaron los cebadores para SMU.759, se realizó PCR, se observaron los amplificados en un gel de agarosa al 1,2%. Resultados: SMU.759 se amplificó en todos los aislados utilizados. Conclusión: el gen SMU.759, que codifica una proteasa, sería un gen constitutivo del genoma de S. mutans.
Dental educators’ views and knowledge of competencies required within a competency framework
Authors: Maart Ronel D. , Adam Razia, Z. , Frantz José M.
Published: October 2021

The aim of the study was twofold; first was to explore and describe dental educators’ views of the competencies required within the AfriMEDS core competency framework. The second was to highlight the views of the dental educators, regarding the alignment of the AfriMEDS core competencies, with the dental curriculum. A case study approach to qualitative inquiry was used. The participants were purposefully selected, and two focus group discussions were conducted. An interview protocol was used to guide the discussions. The gathered data from the discussions were transcribed verbatim, and uploaded to the Atlas ti program for data analysis. Themes were identified from the findings of the thematic analysis. Results Dental educators required some guidance and clarity on the AfriMEDS core competency framework. However, they were able to recognize the competencies related to the AfriMEDS core competency framework. Two of these competencies, evidence-based dentistry, and private practice, were highlighted as core competencies in this current study; however, in AfriMEDS, only certain aspects of this was described. The results of this current study revealed that dental educators were able to make valuable recommendations about the additional competencies requirements for dental graduates.
Metinlerarasılıktan Transmedya Hikaye Anlatıcılığına: Harry Potter
Authors: ELVEREN ARI Beste , GÜRSES KÖSE İlknur
Published: October 2021

Postmodernizm ile birlikte çeşitlenen anlatı yapıları, teknolojinin gelişmesiyle farklı mecralara yayılma olanağı bulmuştur. Transmedya genel olarak büyük bir hikâye yapısına sahip olan anlatıların parçalanarak farklı medyalar üzerinden yayınlanmasını ifade etmektedir. Transmedya hikâye anlatıcılığı, postmodern bir anlatım yöntemi olan metinlerarasılık ve medya içeriklerinin medya araçları arasındaki dolaşımını ifade eden medyalararasılık kavramlarından beslenmektedir. Hayran ve katılımcı kültür odaklı bir yapıya sahip olan transmedya, medyalar arası dolaşımda yayılmacı bir politika izlemektedir. Harry Potter’ın, fantastik türde çocuk romanı olarak başlayan yolculuğu, anlatının çoğullanarak ve izlek değiştirmesi ile birlikte tiyatro, hayran yapımı kısa film, uzun metraj film, mobil oyun, video oyunu şeklinde devam etmektedir. Bu haliyle Harry Potter anlatısı diğer tüm medyalar ve mecralarda yeniden yazılmakta ve metinlerarası ilişkileri pekiştirmektedir. Bu bağlamda, çalışmada Harry Potter evrenine ait olan medya ürünlerinin öncül metinler ile olan ilişkisi; metinlerarası ilişkiler, medya dolaşımı açısından medyalararası ilişkiler ve hikâyenin medyalar arasında çoğullanarak yeniden yazılması bakımından transmedya hikâye anlatıcılığı kapsamında incelenecektir.
Overcoming the Semantic Barrier and Developing the Ability to Use Communicative Tools Part I. Issue. Method
Authors: Soldatenkova E.N.
Published: October 2021

The article is devoted to the problem of the functional structure of communicative action. Based on theoretical analysis and many years of pedagogical experience of working with children with affective pathology (autism spectrum disorders), the author recreates and refines the studies of cultural-historical theory and answers its main question — a method problem: the influence of holistic interfunctional analysis on overcoming semantic bias (central defect and syndrome-forming factor of psychopathology) and the development of a more universal communication form — verbal communication in non-speaking children with autism spectrum disorders in preschool age (by means of restructuring the way the impaired function is realized). The described conditions can be taken into account when constructing an intermediary (lively communicative action) both in the practice of general education (to prevent the occurrence of motivational disorders and increase the age limit) and in working with children with affective pathology (especially with children with autism spectrum disorders).
Unexpected Сonnections: Cultural-Historical Psychologyin a Community Mental Health Setting?
Authors: Thomas P.B.
Published: October 2021

This paper will reflect on the influence of Vygotsky and Luria in my work as an occupational therapist in the community mental health setting of an ‘Activity Centre’ in the National Health Service, between 1991 and 2001. The paper will discuss a limited study, referencing Vygotsky during that period, with the benefit of hindsight and subsequent developments in the field of cultural-historical psychology. The origi¬nal study raised the questions of what evidence could be found to support the application of Vygotsky’s Zone of Proximal Development (ZPD) with a mixed group of adults in a community setting, and how this process of learning might be assessed and evaluated. At the time, these questions were informed by litera¬ture sources no later than 1998, and learning theory was often absent from professional training in mental healthcare. However, I will propose that some models of practice in mental health — particularly those founded in psycho-analytic group therapy and occupational therapy — could be enhanced by a deeper un-derstanding of Vygotsky’s ZPD, Luria’s model of field research, and the discussion of some less established connections in psychoanalytic praxis.
Fear of COVID‐19 among healthcare workers in filiation teams: predictive role of sociodemographic, organizational and resilience factors
Authors: PAK GÜRE Merve Deniz , KARATAŞ Mustafa , ÖZDEMİR Hasan Fehmi , DUYAN Veli
Published: October 2021

sociodemographic, organizational, and resilience factors on the fear of COVID-19 of healthcare workers in the filiation teams.

Materials and Methods: 1028 healthcare workers participated in the study. The sociodemographic questionnaire, The Fear of COVID-19 Scale, and The Resilience Scale for Adults were used. The data were analysed with stepwise multiple linear regression by using the backward elimination method.

Results: The study showed that age and family cohesion are positively significant, while planned future and perception of self are negatively significant explanatory factors on the fear of COVID-19. The fear of COVID-19 is higher in females, and in those; with a high level of education, who have an individual with a chronic disease at home, with a low-income level, who lost a colleague or a family member due to coronavirus, who have an increase in patient burden, and who have problems in access to medical equipment.

Conclusion: It is recommended to improve psychosocial support and organizational conditions for healthcare workers in the filiation teams.
Prevalence and associated factors of urinary incontinence among adult women in primary care
Authors: ALKURT NARÇİÇEĞİ Bilge , YAKAR Burkay , NARÇİÇEĞİ Harun Recep , ÖNALAN Erhan , PİRİNÇCİ Edibe
Published: October 2021

Purpose: The current study aimed to prevalence of urinary incontinence (UI) and related factors in adult women admitted to the family medicine outpatient clinic.

Materials and Methods: This cross-sectional prospective study was conducted in a family health centre between October 2020 and March 2021. Randomly selected 268 adult women were included in the study. The demographic, obstetric, gynecological characteristics and medical history of the participants were obtained with a questionnaire. Urinary incontinence symptoms was assessed using Turkish Version of the International Incontinence Questionnaire Short Form (ICIQ-SF)

Results: The prevalence of UI in study population was 17.5% and according to age grup it was 4.1% at 18-29

years, 10.3% at 30-39 years, 12.0% at 40-49 years, 33.3% at 50-59 years, 46.7% at 60-69 years and 81.8% at ≥70 years old, respectively. Participants with urinary incontinence had higher median age, body mass index (BMI), menopause vintage, and gravida than continent participants. Low education level, drug usage, constipation, menapause (were independently associated with urinary incontinence.

Conclusion: UI is still a common health problem among adult women. We recommend physicians to be questioned about UI symptoms, especially in women over 50 years of age. Further studies are needed to evaluate the effect of the treatment of modifiable risk factors on UI incidence among adult women
The Role of Foreign Tourists in Economic Growth: Evidence from Indonesia
Authors: Azizurrohman Muhammad , Hartarto Romi Bhakti , Lin Yih-Ming , Nahar Faiza Husnayeni
Published: October 2021

Foreign tourism is indicated as one of the important instruments to encourage economic growth in several countries, including Indonesia. However, some studies only focus on the influence of tourist arrivals. Thus, the main objective of this study is to take a deeper look at the contribution of foreign tourism indicators to economic growth in Indonesia. Using panel data analysis from 33 countries between 2006 and 2016, this study applies three models: Pooled Least Square (PLS), Fixed Effect Model (FEM), and Random Effect Model (FEM). Based on the fixed-effect model, this study reveals that foreign tourist arrivals have a significant and positive effect on economic growth. However, other tourism indicators such as length of stay and expenditure of foreign tourists appear to have no contribution to economic growth. From these findings, it can be implied that the Indonesian government should not only attract more tourists to come but also design strategies to encourage tourists to spend more money and stay longer. This study also finds that depreciation of Indonesian currency and visa-free policies have a significant contribution to higher economic growth.
Relationship between anemia, hypoalbuminemia, vitamin D deficiency and quality of life in advanced non-small cell lung carcinoma patients at tertiary hospital in Bali
Authors: Ekaruna I. B. P. , Suryana Ketut , K. Jasminarti D. , Candrawati N. W. , Arisanti N. L. P. Eka , Sajinadiyasa I. G. K. , Rai I. B. N.
Published: October 2021

Background: The main purpose of treatment in patients with advanced lung cancer is more emphasizing on prolonging survival and improving the patient's quality of life (QOL). Micronutrient deficiency has an impact on the patient's QOL. The purpose of this study was to analyse the relationship between biochemical parameters of nutrient deficiency with QOL in patients with advanced non-small cell carcinoma (NSCLC) at Sanglah hospital.Methods: A cross sectional study was conducted in Sanglah general hospital on March-June 2021. Hemoglobin, albumin, and 2.5 (OH) D levels were obtained from patient's serum. The participant’s QOL was measured with EQ-5D-3L questionnaire. Bivariate analysis using chi-square test or Fisher's exact test, and multivariate analysis using logistic regression.Results: A total of 80 participants were included in this study, and 55% had poor QOL. Seventy percent participants had anemia, 36.3% had hypoalbuminemia, and 26.3% had vitamin D deficiency. The QOL of patients with advanced stage NSCLC was significantly associated with hypoalbuminemia (p=0.000) and vitamin D deficiency (p=0.044). Multivariate analysis showed that the most influential factor on the QOL of patients with advanced stage NSCLC was hypoalbuminemia (AOR 9.158; 95% CI 2.150-30.001; p=0.003).Conclusions: Hypoalbuminemia and vitamin D deficiency were significantly related with QOL of advance NSCLC patients. No relationship was found between anemia and the QOL of advance NSCLC patients. Hypoalbuminemia was the most influential factors related to the QOL of advance NSCLC patients.
Comparison between single spin and double spin platelet rich plasma in pain and functional outcome of Osteoarthritis knee: A randomized controlled trial
Authors: Devi Khwairakpam Selina , Singh Akoijam Joy , Singh Longjam Nilachandra , Rajkumari Kanti , Chabungbam Margaret , Moirangthem Monica , Opo Tasso , Rasaily Prashant Kami
Published: October 2021

Background: Osteoarthritis (OA) is condition characterised by progressive degeneration of joint cartilage, eventually leading to deformity of the joint. OA causes pain and disability and impacts on quality-of-life. Intra-articular platelet rich plasma gives favourable outcomes in OA knee; however, efficacy may be affected by method of preparation. Hence, this study comparing single spin and double spin platelet-rich plasma (PRP).Methods: A randomised controlled trial done among patients of OA who visited Department of Physical Medicine and Rehabilitation, Regional Institute of Medical Sciences, Imphal during August 2019-July 2021. Patients with OA knee having radiological findings of Kellgren Lawrence (KL) grade 2 and 3 (n=62) randomized into single spin PRP, (n=31) and double spin PRP, (n=31) groups and intra-articular PRP injection was given.Results: Baseline characteristics were not statistically significant. At the end of 1 week, improvement in mean difference of VAS was observe however not statistically significant (p=0.71). At end of 12 weeks and 24 weeks, there were statistically significant improvement in both mean difference of VAS (p=0.00) and WOMAC (p=0.002). Post intervention, out of the single spin PRP group, (64.51%, n=20) had complaints of adverse effects swelling, pain, redness whereas (6.45%, n=2) patients who received double spin PRP had adverse effects.Conclusions: Platelet rich plasma obtained by double spin method has long term improvement in both pain and function in patients with KL grade 2 and 3 OA knee than PRP from single spin method. Patient who received single spin PRP has more frequent post injection flare ups.
Timing methylprednisolone pulse therapy in COVID-19 infection-finding the sweet spot: a case series
Authors: Kumar Anupam , Singh Suhail , Sherawat Vikas
Published: October 2021

Steroid therapy has been proven beneficial in the treatment of SARS-CoV2 in various trials all around the world. However, the dosing and timing of this therapy are crucial and still under debate. Studies exist regarding the use of Pulse IV therapy of steroids in this illness, but it has still not been widely used and accepted throughout the world. Here we describe four cases of SARS-CoV2 who presented to a tertiary care center in India within the first week of illness, with moderate to severe disease activity. These patients were treated with Pulse doses of intravenous MethylPrednisolone. All four patients showed positive outcomes in terms of oxygen requirement and early recovery.
Indian consensus statement on the management of metastatic colorectal cancer
Authors: Vaid Ashok K. , Mohapatra Prabrajya N. , Desai Chirag
Published: October 2021

In India, the annual incidence rates for colon cancer are 4.4 (males) and 3.9 (females) per 100,000. A common guideline for the management of metastatic colorectal cancer (mCRC) in the Indian subcontinent is lacking. Four virtual advisory board meetings consisting of a panel of 31 experts were conducted to discuss and arrive at a consensus on the treatment patterns and clinical evidence on the management of mCRC in Indian patients. The consensus covered the entirety of treatment patterns suited for the Indian subcontinent and its alignment with Pan-Asian adapted European Society for Medical Oncology guidelines. Recommendations were provided for choosing the first- and second-line agents for treatment. Types of, recommendations for, and management using salvage therapy and immunotherapy as well as management of adverse effects were discussed. Thus, the mCRC consensus is expected to serve as effective and readily available guidance for practicing oncologists across India.
Dysphagia intervention in NICU set up: a report of case studies in an Indian public hospital
Authors: Hattiangadi Gayatri A. , Gore Geeta B. , Malik Sushma
Published: October 2021

A retrospective study was conducted in the Neonatal Intensive Care Unit (NICU) of a public hospital in Mumbai, India wherein 13 neonates with varying pathophysiologies were taken up for swallowing intervention. Of these, 7 neonates had history of prematurity, 1 was born of twin birth with prematurity, 3 had clefts of lip/palate and 2 had Pierre Robin Syndrome. For 7 neonates with prematurity, the swallowing regimen consisted of oro motor intervention (OMI) followed with therapeutic oral feeds. With improved tolerance of oral feeds while maintaining airway safety, they were graduated to oral feeds progressively increasing in volume until they reached optimum prescribed oral feeds. 6 out of 7(86%) progressed to breast feeds while1 succumbed to medical complications. 3 babies with CLP graduated to complete oral feeds through bondla, when they were fitted with obturators and had swallowing intervention but were unable to move to breastfeeds while in NICU. 2 babies with PRS could not tolerate oral feeds even after multiple sessions and had to be maintained on orogastric feeds. 1 infant, one of a twin delivery with prematurity although was showing improvement to OMI succumbed to medical complications. Among these neonates, those with prematurity showed the maximum improvement with swallowing intervention followed by infants with CLP. Co-morbidities such as prematurity in twin births worsened the prognosis as did a disorder such as PRS. This preliminary study, done on a small sample, stressed the importance of swallowing intervention in neonates with high risk factors by the SLP in the NICU in an Indian set up.  
A rare case of necrotizing fasciitis of eyelid in a young immunocompetent lady- case report and review of literature
Authors: Venkataramani Nithya , Muralidhar Sonali , Sachidananda Ravi
Published: October 2021

Necrotising fasciitis of the periorbital region is a rare condition where there is destruction of the periorbital soft tissue with potential of rapid spread causing significant morbidity and mortality. It is generally seen in immuno suppressed individuals following trivial trauma. Here we present a case of periorbital necrotising fasciitis in a young immonocompetent lady with emphasis on early identification and aggressive treatment to prevent loss of vision and mortality.
Heterotrophic ossification post total knee arthroplasty in a patient with rheumatoid arthritis: a case report
Authors: Veliyil Aswin Thankachan , S. Dileep , Mathew Renjit John , John John Thayyil
Published: October 2021

Even though minor degrees of heterotrophic ossification are common in total knee arthroplasty, it is of little clinical significance. But severe degrees of heterotrophic ossification are very rare after total knee arthroplasty. Here we discuss about a 70 years old woman who initially had excellent post-operative range of movements after cemented total knee arthroplasty, but later presented with knee pain, swelling and loss of range of movements after 3 months. X ray showed severe heterotrophic ossification around knee near the quadriceps tendon. She was treated conservatively with non-steroidal anti inflammatory drugs and physiotherapy. After a period of 3 months of physiotherapy, patient regained the lost range of movements and is currently under follow up for the past 1 year. Hence this case instantiates that even in cases of severe Heterotrophic Ossification after total knee arthroplasty, non-operative treatments such as physiotherapy with anti-inflammatory drugs should be the primary option to treat the stiffness before considering surgery.

 
Collectors in Mycenaean Greece and the Deliverance of Animals in the Series Wu from Thebes
Authors: Loginov Alexandr
Published: October 2021

The complex of Thebes tablets Wu makes clear, that the gathering of animals for a sacrifice could be produced in two ways: using different obligations introduced by the state (together with the institutions named qe-te-a2, a-ko-ra) or due to those who belonged to upper social class. The same man from upper class could deliver the animal for a feast as a private person (by putting a seal near the ideogram of the animal) or as bureaucrat of the palace administration, ensuring the fulfillment of obligations imposed by the palace. In the first case he had the honour to act as a representative of the upper class, in the second he acted as a bureaucrat. This conclusion corresponds to the idea of Kyriakidis who pointed out the ambiguity of collectors' social status: they used to receive rent from their own herds and workshops and from those of the palace as well (which they administered).
Cities of Crimea in the Works of Arab Geographers of the 12th — 14th Centuries
Authors: Konovalova Irina
Published: October 2021

The paper is devoted to a comparative analysis of information about the cities of the Crimean peninsula in the works of Arab geographers of the 12th — 14th centuries (al-Idrīsī, Ibn Sa‛īd al-Maghribī and Abū al-Fidā’. Despite the continuity of the works of these authors — both in general and in relation to information about the Crimean cities — each of them used his own sources to describe the Crimea, which reflected the main directions of the trade routes passing through the peninsula. The analysis carried out in the paper made it possible to establish the geographical nomenclature of the port cities of Crimea in the 12th — 14th centuries, their role in the Black Sea navigation during this time, and also to reconstruct the map of the navigation routes of this section of the Black Sea.
Madrid in the Late 16th Century: Paradoxes of a City that Suddenly Became a Capital
Authors: Védyushkin Vladimir
Published: October 2021

The article analyzes the historical experience of Madrid, which became the capital of Spain in 1561. The reasons for Philip II’s reluctance to establish the capital in Valladolid or Toledo, which previously often served as royal residences, are considered. The analysis of the ideas about Madrid in the texts of such authors of the 16th — early 17th centuries as Luis Cabrera de Córdoba, Lucio Marineo Siculo, Pedro de Medina shows that even before acquiring the capital status, it was a notable city of Castile, which had significant advantages, so that the choice in its favour was logical, although not predetermined. By the time the Court was transferred to Madrid, on the initiative of Philip II, a large-scale program of urban reforms was prepared, in which the features of Renaissance urbanism are clearly visible. The unusually rapid and uncontrolled growth of the city’s population after 1561 required the authorities to establish mechanisms for billeting courtiers and officials into the houses of Madrid residents and then standards for housing construction; the article analyzes the royal decree of 1567 dedicated to this matter. The most important tasks of the authorities were also to provide citizens with food, clean the streets and fight crime. The Royal decree of 1585 shows the attention of the authorities to these issues; the content and role of this decree are also discussed in the article. In general, the conceived program of urban reforms faced great difficulties, but the transformations that were carried out played an essential role in the history of Madrid.
Aachen — the Second Rome: a City as a Symbol of Power in Poetic Carolingian Texts
Authors: Petrova Maya
Published: October 2021

The paper deals the construction of Aachen as a symbol of the power of Charlemagne (742/4 — 814). It discusses the poetic Carolingian texts, which played an important role in the formation of the medieval ideology of the unity of the City and the power of its creator. It is shown that the most striking example of the statement of such a worldview is the third book (v. 1—536) of the anonymous epic poem (not fully preserved), known in the early Middle Ages under the title “Charlemagne and Pope Leo” (Karolus Magnus et Leo Papa). It is noted that this text, containing a description of the construction of the Second Rome — Aachen, influenced the subsequent Carolingian poetic tradition, serving as a turning point in the development of narrative poetry during the reign of Charlemagne.
The Middle Ages in the Landscape of the Present-Day Pereslavl-Zalessky
Authors: Shaduntc Elena
Published: October 2021

Among ancient Russian towns, Pereslavl-Zalessky stands out for the rare preservation of its historical town-planning structure. The basis for such estimation is provided by the evidence of sources on the town’s history during the 12th — 17th centuries and a comparative analysis of cartographical documents of the early modern time. The views on the formation of Old Russian towns and assessment of the factors affecting the town-planning have recently undergone considerable changes. The comparison of historical and archival as well as archaeological evidence with the present-day topography of Pereslavl allows us to trace the modification of the planning structure that has retained not only separate architectural objects of the 12th — 17th centuries but also parcels of the medieval town layout. The article presents examples of the ‘exceptions to the rule’ during the execution of a regular plan at the end of the 18th century that, together with historical evidence on the composition and occupations of the trading quarter’s population, permit to more precisely determine the historical peculiarity of Pereslavl.
The King and His Kingdom: a Notion of the Tierra in the Second Partida of Alfonso X
Authors: Marey Alexander
Published: October 2021

The article analyzes the use of the concept “land” (tierra) in several texts from the era of Alfonso X the Wise (1252—1284). The focus is on two chapters of the “Second Partida”, which contains detailed regulation of the social and political structure of the kingdom. In addition to the “Second Partida”, the author examines this concept in the acts of Cortes of Alfonso’s reign, in other legal codes of the Wise King (“Fuero Real” and “Especulo”), as well as in the “Chronicle of Alfonso X”. The use of the latter source is because, although it was compiled later (c. 1348), it contains texts written under Alfonso X. According to the study results, the author identifies several central registers of the use of the concept of tierra in the texts he selected. In the texts of the acts of the Cortes, “Fuero Real” and “Especulo”, this word most often means either land, as a territory covered by the jurisdiction of the king or judges, or as an object of private property rights. In the “Second Partida” appears one meaning more — the earth as the embodiment of the nutritive soul of the people, a link between the king and the people, an integral part of the mystical-political body of the kingdom. In contrast to the previous, more traditional connotations, based on the texts of the Roman and canonical legal traditions, in this case, the source of inspiration for Alfonso X’s collaborators is most likely the Arabic commentaries on Plato’s political dialogues.
Las relaciones intergubernamentales como problema y el territorio como argumento: políticas de salud en Argentina (2008/2014)
Authors: Chiara Magdalena
Published: October 2021

Aunque con menor intensidad que en otros cam- pos de las políticas, en la última década el sector salud ha sido escenario de distintos avances en la recuperación del papel del Estado. Con diseños or- ganizacionales diferentes, los dispositivos de polí- ticas sectoriales tejieron relaciones en el marco de las limitaciones que impone una matriz desigual y muy fragmentada, incluso dentro del propio sub sector estatal, que resultó del federalismo y la des- centralización. Se construyeron así arreglos singu- lares en el marco de las restricciones impuestas por la trama de las relaciones intergubernamentales que caracterizan al sector salud en Argentina. El trabajo analiza un conjunto de iniciativas que, apelando al enfoque territorial, buscaron contrastar con la ló- gica sectorial que anima las acciones ministeriales. Los casos analizados muestran distintas nociones de territorio y modos también diferentes de organizar las relaciones políticas entre niveles de gobierno.
El dilema de los híbridos sociales como alternativa de producción.
Authors: Pérez Verónica
Published: October 2021

La historia reciente de los ferrocarriles metropoli- tanos de pasajeros se caracteriza por la implemen- tación de sucesivas transformaciones en las formas sociales de organizar su prestación. Las mismas han tenido como común denominador un creciente protagonismo del Estado en la actividad, con resul- tantes heterogéneas que difcultan un balance posi- tivo de la etapa. La hipótesis propuesta es que una de las principales condiciones que permiten compren- der esta situación radica en la confguración de una particular relación entre Estado, empresarios y sin- dicalismo empresario, que ha sido conceptualizada como simbiosis colusiva. El período comprendido en este estudio inicia en 2003 y fnaliza en 2015.
Aportes para la revisión y análisis crítico de experiencias de planificación territorial municipal: Colón (Pcia. de Buenos Aires).
Authors: Cirio Gastón
Published: October 2021

El trabajo constituye una revisión crítica de una experiencia concreta de planifcación territorial en la escala municipal, procurando establecer articula- ciones entre los abordajes teórico-metodológicos que nutren el debate actual sobre políticas de pla- nifcación territorial y la experiencia analizada. El caso de Colón, Buenos Aires, es abordado a partir de tres objetivos específcos: a) describir la expe- riencia; b) analizar los principios teórico-meto- dológicos que sustentan las prácticas y elecciones realizadas; y c) ofrecer lineamientos para el debate en torno a los principales nudos problemáticos de la experiencia y los resultados obtenidos. Se com- binan para ello, técnicas de análisis documental de múltiples fuentes desde una óptica refexiva y au- tocrítica. Por último, se exponen unas breves líneas a modo de refexiones fnales.
La transformación de las funciones de la asociatividad en una cooperativa de cartoneros: de la representación al trabajo productivo
Authors: Tagliafico Juan Pablo , García Adriana , Schamber Pablo
Published: October 2021

En las últimas décadas, los recuperadores urbanos de residuos y los procesos de formación de coo- perativas han sido objeto de estudio de numerosos análisis. Sin embargo, no son muchos los trabajos que indagan en la heterogeneidad de las coope- rativas de recuperadores de la ciudad de Buenos Aires y la especifcidad de cada proceso de forma- ción. Como un modo de comenzar a plantear esta cuestión, nos proponemos indagar en el proceso de conformación de una cooperativa en el perío- do 2001-2015, identifcando sus particularidades y dando cuenta de los efectos que ha tenido en los cartoneros la participación en esta nueva forma de asociatividad. Nos interesa, además, analizar las transformaciones subjetivas de los propios actores en relación con los procesos asociativos. Las pre- guntas de las que partimos es para qué se asociaron, para qué formaron cooperativas.
Tendencias recientes de las políticas de vinculación científico-tecnológicas dirigidas a las universidades argentinas
Authors: Di Meglio Fernanda
Published: October 2021

El artículo analiza las transformaciones que atravesaron las universidades argentinas en los últimos años y los cambios contextuales que marcaron las relaciones de las universidades con el ámbito productivo. Asimismo, describe las principales características y tendencias del contexto normativo e institucional en el cual las universidades desempeñan sus actividades. En tercer lugar, se indaga sobre los principales programas provinciales y nacionales orientados a promover la vinculación entre la universidad y el sector productivo. Los resultados muestran dos tendencias predominantes: la federalización de la políticade ciencia y tecnología y una territorialización de las políticas de vinculación científico- tecnológica que se desprenden de los programas propuestos por distintos organismos del plano nacional y provincial.
El neoliberalismo puesto en perspectiva. Para una revisión de nuestras concepciones críticas
Authors: Méndez Pablo Martín
Published: October 2021

Este artículo pretende abrir algunos puntos necesariosde debate para avanzar en la re-conceptualizacióndel “neoliberalismo”, desplazando el análisiscrítico un poco más allá de los supuestos habituales.¿Cómo entendemos hoy al neoliberalismo?¿En qué nos apoyamos para criticarlo? Al neoliberalismose lo suele identificar en gran parte de laliteratura con una suerte de regreso hacia el pasado, yasea en la forma de la ortodoxia económica o biendel intervencionismo represivo. Sin dar respuestasúltimas y definitivas, nos preguntamos aquí cómolos programas neoliberales de gobierno ganan unaamplia adhesión en la población, cómo interpelannuestras conductas y creencias, más allá de la ortodoxiaeconómica y la represión.
Estado: Perspectivas Posfundacionales. Emmanuel Biset y Roque Farrán (compiladores)
Authors: Barbosa Sebastián Cruz
Published: October 2021

Esta obra tiene una gran virtud inicial y es que, talvez, por primera vez se compila un conjunto detextos analíticos e interpretativos sobre cómo haabordado la cuestión del Estado el llamado Posfundacionalismo.Se trata de artículos que trabajan enesta clave con autores de una talla intelectual nodalen el corpus de la Teoría Política Contemporánea:Agamben, Badiou, Butler, Deleuze, Derrida, Foucault,Laclau, Poulantzas, Ranciere y Zizek.
A Rare Case of Bilobed Giant Peritoneal Loose Body
Authors: Nasrin Salma , Mahata Susmita , Mandal Sumanta Kumar
Published: October 2021

A 50-year-old male patient was referred to Department of Radiodiagnosis for evaluation of a longstanding intermittent abdominal pain associated with a palpable mass migrating in different quadrants of the abdomen and had gradually increased in size over last few years. The initial ultrasonographic (USG) evaluation revealed a well circumscribed bilobed hypoechoic pelvic solid space occupying lesion (SOL) with central calcific foci. Subsequent contrast enhanced computed tomography (CECT) imaging showed a 10.1 x 7.5 x 5.8 cm, bilobed non-enhancing pelvic mass with central dense calcific foci and concentric soft tissue layers of different attenuation. The mass was diagnosed to be a giant peritoneal loose body (gPLB) and confirmed by surgical exploration.