bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimizing radar scan strategies for tracking isolated deep convection using observing system simulation experiments
Authors: Oue Mariko , Saleeby Stephen M. , Marinescu Peter J. , Kollias Pavlos , van den Heever Susan C.
Published: August 2022

Abstract. Optimizing radar observation strategies is one of the most
important considerations in pre-field campaign periods. This is especially
true for isolated convective clouds that typically evolve faster than the
observations captured by operational radar networks. This study investigates
uncertainties in radar observations of the evolution of the microphysical
and dynamical properties of isolated deep convective clouds developing in
clean and polluted environments. It aims to optimize the radar observation
strategy for deep convection through the use of high-spatiotemporal
cloud-resolving model simulations, which resolve the evolution of individual
convective cells every 1 min, coupled with a radar simulator and a cell
tracking algorithm. The radar simulation settings are based on the Tracking
Aerosol Convection Interactions ExpeRiment (TRACER) and Experiment of Sea
Breeze Convection, Aerosols, Precipitation and Environment (ESCAPE) field
campaigns held in the Houston, TX, area but are generalizable to other field
campaigns focusing on isolated deep convection. Our analysis produces the
following four outcomes. First, a 5–7 m s−1 median difference in
maximum updrafts of tracked cells is shown between the clean and polluted
simulations in the early stages of the cloud lifetimes. This demonstrates
the importance of obtaining accurate estimates of vertical velocity from
observations if aerosol impacts are to be properly resolved. Second,
tracking of individual cells and using vertical cross section scanning every minute capture the evolution of precipitation particle number concentration and size represented by polarimetric observables better than the operational radar observations that update the volume scan every 5 min. This approach also improves multi-Doppler radar updraft retrievals above 5 km above ground level for regions with updraft velocities greater than 10 m s−1. Third, we propose an optimized strategy composed of cell tracking by quick (1–2 min) vertical cross section scans from more than one
radar in addition to the operational volume scans. We also propose the use
of a single-RHI (range height indicator) updraft retrieval technique for cells
close to the radars, for which multi-Doppler radar retrievals are still
challenging. Finally, increasing the number of deep convective cells sampled
by such observations better represents the median maximum updraft evolution
with sample sizes of more than 10 deep cells, which decreases the error
associated with sampling the true population to less than 3 m s−1.
Modeling the effects of alternative crop–livestock management scenarios on important ecosystem services for smallholder farming from a landscape perspective
Authors: Pfeiffer Mirjam , Hoffmann Munir P. , Scheiter Simon , Nelson William , Isselstein Johannes , Ayisi Kingsley , Odhiambo Jude J. , Rötter Reimund
Published: August 2022

Abstract. Smallholder farming systems in southern Africa are characterized by low-input management and integrated livestock and crop production. Low yields and dry-season feed shortages are common. To meet growing food demands, sustainable intensification (SI) of these systems is an important policy goal. While mixed crop–livestock farming may offer greater productivity, it implies trade-offs between feed supply, soil nutrient replenishment, soil carbon accumulation, and other ecosystem functions (ESFs) and ecosystem services (ESSs). Such settings require a detailed system understanding to assess the performance of prevalent management practices and identify potential SI strategies. Models can evaluate different management scenarios on extensive spatiotemporal scales and help identify suitable management strategies. Here, we linked the process-based models APSIM (Agricultural Production Systems sIMulator) for cropland and aDGVM2 (Adaptive Dynamic Global Vegetation Model) for rangeland to investigate the effects of (i) current management practices (minimum input crop–livestock agriculture), (ii) an SI scenario for crop production (with dry-season cropland grazing), and (iii) a scenario with separated rangeland and cropland management (livestock exclusion from cropland) in two representative villages of the Limpopo Province, South Africa, for the period from 2000 to 2010. We focused on the following ESFs and ESSs provided by cropland and rangeland: yield and feed provision, soil carbon storage, cropland leaf area index (LAI), and soil water. Village surveys informed the models of farming practices, livelihood conditions, and environmental circumstances. We found that modest SI measures (small fertilizer quantities, weeding, and crop rotation) led to moderate yield increases of between a factor of 1.2 and 1.6 and reduced soil carbon loss, but they sometimes caused increased growing-season water limitation effects. Thus, SI effects strongly varied between years. Dry-season crop residue grazing reduced feed deficits by approximately a factor of 2 compared with the rangeland-only scenario, but it could not fully compensate for the deficits during the dry-to-wet season transition. We expect that targeted deficit irrigation or measures to improve water retention and the soil water holding capacity may enhance SI efforts. Off-field residue feeding during the dry-to-wet season transition could further reduce feed deficits and decrease rangeland grazing pressure during the early growing season. We argue that integrative modeling frameworks are needed to evaluate landscape-level interactions between ecosystem components, evaluate the climate resilience of landscape-level ecosystem services, and identify effective mitigation and adaptation strategies.
Peran BUMDES Tanjung Jaya Mandiri dalam Pemberdayaan Ekonomi Masyarakat Desa Tanjung Lanjut Kabupaten Muaro Jambi
Authors: Firdaus Firdaus , Helena Dida
Published: August 2022

Tujuan penelitian ini adalah untuk mendeskripsikan dan menganalisis peran BUMDES Tanjung Jaya Mandiri dalam pemberdayaan ekonomi masyarakat Desa Tanjung Lanjut Kabupaten Muaro Jambi. Penelitian ini menggunakan metode deskriptif kuantitatif dengan pendekatan triangulasi, dimana sampel yang digunakan adalah 78 orang responden (masyarakat) yang dipilih secara acak (random sampling), dan 2 orang informan pendukung yaitu Direktur BUMDES Tanjung Jaya Mandiri dan Kepala Desa Tanjung Lanjut yang dipilih secara purposive. Data hasil wawancara dianalisis secara kualitatif dengan menggunakan teknik analisis kualitatif model analisis interaktif. Sementara data hasil observasi dan isian kuesioner dianalisis secara statistik deskriptif. Hasil penelitian ini didapatkan bahwa perkembangan BUMDES Tanjung Jaya Mandiri dapat dinyatakan sudah maju, baik dilihat dari aspek manajemen, sosial, ekonomi, dan lingkungan. Hal ini dikarenakan beberapa faktor, yaitu; peran kepala desa sebagai pengendali pelaksanaan kegiatan pengelolaan BUMDES, partisapasi dan tindakan proaktif dari masyarakat, dan adanya team buliding dalam pengelolaan sumber daya manusia. Terkait dengan peran BUMDES dalam pemberdayaan ekonomi masyarakat, secara keseluruhan memiliki tingkat kontribusi peran yang tinggi, baik pada dimensi pemungkinan, penguatan, perlindungan, penyokongan, dan pemeliharaan. Dari kelima dimensi pemberdayaan tersebut BUMDES Tanjung Jaya Mandiri memberikan kontribusi peran tertinggi pada dimensi penyokongan (supporting), yang berarti bahwa BUMDES tersebut dalam memberdayakan ekonomi masyarakat berfokus pada upaya pemberian bimbingan dan dukungan kepada masyarakat lemah agar mampu menjalankan peran dan fungsi kehidupannya, seperti memberikan kemudahan akses pada seluruh masyarakat desa terhadap sumber daya yang dibutuhkan dalam meningkatkan pendapatan. Berdasarkan hasil temuan ini disarankan kepada pengelola BUMDES Tanjung Jaya Mandiri diharapkan lebih memperhatikan upayanya dalam menciptakan suasana atau iklim yang memungkinkan potensi masyarakat berkembang secara optimal, serta menerapkan prinsip-prinsip pengelolaan BUMDES berbasis pemberdayaan masyarakat pada setiap unit usaha.
ASSOCIAÇÃO DO NURSING ACTIVITIES SCORE COM DESFECHOS DE PACIENTES CRÍTICOS
Authors: Santos David Da Silva , Marques Cleidinaldo Ribeiro de Goes , Santos Iris Aline Gomes , Neta Mirena Siqueira Costa , Almeida Hendyara Oliveira Carvalho , Santos Eduesley Santana
Published: August 2022

Objetivo: analisar a associação do Nursing Activities Score com desfechos apresentados nos pacientes em Unidade de Terapia Intensiva. Método: trata-se de uma análise transversal de um estudo do tipo coorte prospectivo, utilizado um instrumento elaborado pelos pesquisadores centrais, com o foco ao Nursing Activities Score, que pontua a necessidade de cuidados de enfermagem em 24 horas. Resultados: houve 50 participantes de cada sexo, em sua maioria procedente da emergência (74%), acometidos por distúrbios cardiovasculares (31%) e com Hipertensão Arterial Sistêmica como doença de base (58%). Durante a sua internação, prevaleceu o uso de noradrenalina e fentanil (ambos com 14%) e o uso de SVD (35%). No desfecho, observou que 47% desenvolveram infecção, 37% usaram ventilação mecânica por mais de 48 horas, 29% desenvolveram lesão renal aguda e 27% evoluíram ao óbito. Conclusão: o Nursing Activities Score permitiu traçar o perfil clínico dos pacientes, e associar uma maior carga de trabalho aos pacientes com desfechos prejudiciais.
SAÚDE DA MULHER: MANUTENÇÃO DA GRAVIDEZ EM GESTANTES
Authors: Fonseca Adrielly Cristiny Mendonça , Pereira Jessica De Souza , Aviz Luciana Emanuelle De , Reis Nanni Moy , Oliveira Érika Patrícia De , Leão Esteliane Da Conceição , Rodrigues Rosane Do Nascimento , Valois Rubenilson Caldas
Published: August 2022

Objetivo : revisar e analisar a literatura sobre as principais alterações fisiológicas que ocorrem no corpo da mulher durante uma gestação. Método : trata-se de um estudo de análise bibliográfica, descritivo, tipo de revisão de literatura, com buscas realizadas durante o período de 01 a 17 de abril de 2020 nas bibliotecas eletrônicas Biblioteca Eletrônica Científica Online (SciELO) e Biblioteca Virtual em Saúde ( BVS))Selecionados-se 19 artigos, os dados não foram processados no software IRAMUTEQ® e analisados descritivamente pelo método de Reinert. Resultados : organizar sete classes, destas quatro categorias: Classe 1, 4 e 7 - Alterações fisiológicas no peso e avaliação nutricional na gestação;Classes 2 e 3 - Processo educativo sobre pirâmide nutricional para um desfecho saudável da gestação; Classe 6 - A importância das alterações hematológicas durante uma gestação; Classe 5 - Benefícios da vitamina D na saúde e no longo ciclo gravídico e pós-natal. Conclusão : Identificou-se, que é fundamental o conhecimento das mudanças fisiológicas para que seja ofertado como condições assistenciais solicitadas, com intuito de evitar complicações. Descritores : Mulheres; Gestantes; Gravidez; Manutenção da gravidez; Edema; Saúde da Mulher.
DO PLANEJAMENTO À MATERNIDADE: MOTIVAÇÕES PARA GESTAR NA ADOLESCÊNCIA
Authors: Rossetto Maira , Felicte Sandi , Cubas Lettizia Wessler
Published: August 2022

Objetivo: identificar as características socioeconômicas e analisar as motivações que permeiam o planejamento da gestação na adolescência. Método: pesquisa qualitativa, desenvolvida por meio de entrevista semi-estruturada com 14 adolescentes que planejaram a gestação. As entrevistas foram gravadas, transcritas e analisadas por meio da análise de conteúdo temática. Os dados foram coletados entre dezembro de 2020 e fevereiro de 2021. Resultados: foram organizadas três categorias de análise: principais características das participantes da pesquisa e seus familiares; motivações para o planejamento da gestação na adolescência; repercussões da escolha da gestação e da vivência da maternidade na adolescência. Considerações Finais: a projeção do futuro está centrada na constituição da sua família, motivadas pelo ambiente sociocultural que fazem parte. Os demais planos foram adiados, mas ao passo que as adolescentes experimentaram a maternidade se sentiram realizadas. Evidencia-se que a gestação não se resume a perdas sociais, mas também novas aspirações e motivações para futuro.
CULTURA ORGANIZACIONAL E CARACTERÍSTICAS DO PLANEJAMENTO EM CENTROS DE SAÚDE
Authors: Schlickmann Monique Haenscke Senna , Lanzoni Gabriela Marcellino de Melo , Erdmann Alacoque Lorenzini
Published: August 2022

Objetivo: Caracterizar a cultura organizacional e o planejamento dos centros de saúde com resultados contrastantes, segundo os indicadores de saúde. Método: estudo de casos múltiplos, composto por quatro casos com resultados contrastantes. Foram realizadas observação não participante e entrevista semiestruturada com 25 profissionais de saúde, entre eles coordenadores dos centros de saúde, profissionais de nível superior das equipes, apoiadores do Distrito Sanitário e um profissional da Secretaria Municipal de Saúde. Como técnica analítica, foi utilizada a síntese cruzada dos dados. Resultados: o trabalho coletivo foi uma das características dos centros de saúde com resultados expressivos, sendo o perfil do coordenador um fator positivo para a equipe. Os casos com resultados inexpressivos são marcados pela falta de profissionais e problemas interpessoais. Conclusão: a cultura de trabalho e o perfil do coordenador influenciam diretamente os resultados alcançados. A alta demanda de atendimentos são problemas comuns às equipes.
ESTUDOS EXPERIMENTAIS DESENVOLVIDOS POR ENFERMEIROS BRASILEIROS: REVISÃO INTEGRATIVA
Authors: Cannavan Priscila Moreno Sperling , Aoki Roberta Nazario , De Almeida Angélica Olivetto , Carvalho Luciana Aparecida Costa , Barbosa Luara De Carvalho , Bueno Giselli Cristina Villela
Published: August 2022

Objetivo: identificar a produção nacional da enfermagem brasileira de estudos experimentais nos últimos cinco anos. Método:  revisão integrativa realizada nas bases de dados, MEDLINE, BVS, Embase, CINAHL e Scopus. Para a estratégia de busca utilizou-se os descritores: “Ensaio Clínico Controlado”, “Ensaio Clínico”, “Ensaio Clínico Controlado Aleatório” e “Pesquisa em Enfermagem”. Como critérios de inclusão estabeleceu-se: artigos originais; entre os anos de 2015 a 2020; nos idiomas português, inglês e/ou espanhol e com pontuação cinco no escore de Jadad. Resultados: Foram analisados 16 artigos com escore cinco na escala de Jadad, que contemplam três premissas: randomização, cegamento e descrição de perdas adequadamente. Os estudos foram categorizados conforme enfoque das pesquisas. Identificou-se quatro grandes áreas de conhecimento: práticas integrativas, saúde do adulto-idoso, saúde materno-infantil e estomaterapia. Na temática de práticas integrativas os estudos demonstraram eficácia dessas práticas, enquanto na área de saúde adulto-idoso e materno-infantil prevaleceram estudos de intervenções educativas; estudos de estomaterapia abordaram terapias tópicas que auxiliam no processo de cicatrização tecidual/prevenção de lesões de pele. Conclusão: Identificou-se que o principal enfoque dos estudos com o método experimental por enfermeiros brasileiros pertencia a quatro grandes áreas de conhecimento da saúde e abordaram questões educativas e intervenções clínicas da prática da enfermagem.
Water hyacinth producing bio-hydrogen by Klebsiella oxytoca ATCC 13182 and their optimization
Authors: Tandon Mona , Thakur Veena , Sao Kunjlata , Jadhav Shailesh Kumar
Published: August 2022

Our energy requirements are almost totally provided by carbon containing fossil sources such as oil, coal and nature gas, but they cause serious environmental problems during combustion such as CO2 emission and climate changes. Bio-hydrogen production from Klebsiella oxytoca ATCC 13182 and water hyacinth was taken as a substrate. Water hyacinth are good source of cellulose and hemicelluloses content used for bio-hydrogen production. This research paper includes the effect of age of inoculation, volume of inoculation and acid pre-treatment (concentrated sulfhuric acid) on bio-hydrogen production along with their specific hydrogen production rate (SHPR), carbon consuming efficiency (CCE) and pH.
Production of Bioelectricity using Microbial Fuel Cells Fed with Synthetically Designed Wastewater
Authors: Meshram Reena , Jadhav Shailesh Kumar
Published: August 2022

Microbial fuel cells (MFCs) are the electrochemical systems that harness electron from the reduction of organic compounds using microbes as a catalyst. 3 combinations from 4 electrodes that are, Zn (14.9cm×4.9cm), Carbon (14cm×1.5cm), Cu (14.9cm×4.9cm) and Al (14cm×4.5cm) were assessed . Zn-C, as an anode-cathode combination produced maximum voltage of 1.1±0.03V and current 1.5±0.12mA. In present study,gram negative non-fermentative staphylococcus bacterium was isolated from a mediator-less microbial fuel cell, fed with rice bran oil refinery wastewater operated in fed-batch manner. The isolate produced potential of 1.01±0.01V and current of 1.24±0.03mA using synthetic wastewater. The newly isolated bacterium has potential of generating electricity in MFC system and may hold many possibilities with different wastewater as well as in practical applications.
Use of InstantDNA card for molecular detection of Banana bunchy top virus by PCR in Musa sp.
Authors: Singh Vikram , Quraishi Afaque
Published: August 2022

For producing reliable and reproducible results via Polymerase chain reaction (PCR) for applications like molecular diagnostics for plant pathogens and plant molecular biology requires good quality DNA. One of the disadvantages of using traditional methods for DNA extraction and storage is the utilization of expensive reagents and equipments. The current study attempts for rapid and reliable method for DNA extraction and detection of Banana bunchy top virus (BBTV) within banana material using InstantDNA cards. This is the first successful application of InstantDNA card for extraction of banana viruses, particularly for BBTV.
Review on production technique and nutritional status of Calocybe indica (P and C)
Authors: Khalkho Sharon , Koreti Deepali , Kosre Anjali , Jadhav S.K. , Chandrawanshi Nagendra Kumar
Published: August 2022

Calocybe indica or milky white mushroom, it’s an indigenous edible mushroom originates from India and apart from India, it is also gaining considerable importance in other tropical countries like Bangladesh, Malaysia, China and Singapore. It has an attractive fruiting body, pleasant white color, highly nutritious, long shelf life, require less time to grow, its cultivation process is easy and economical. C. indica is rich in metabolites including protein, lipid, carbohydrate, and dietary fibers. C. indica is a micro-fungus, they accumulate nutrients as well as minerals from the substrate in which they grow. Because of these feature, C. indica can be a good candidate for making and use it as an enriched food source. Enrichment of C. indica is the new way for mushroom quality improvement. By using a different type of renewable and cheaper supplementation substrates, we can minimize the overall production cause and makes a better quality of C. indica for consumption, as well as nutraceutical development etc. Enriched mushroom cultivation and production can helpful for sustainable development.
Therapeutic and safety aspects of Amrita (Tinospora cordifolia)
Authors: Srivastava Arpita , Sur Arunima , Nayak Kush Kumar
Published: August 2022

For beneficial value medicinal plants have been widely used for humankind. Nature is a source of curative resources for so many years as well as a surprizing total of recent drugs have been isolated from it. Outmoded drug is the utmost realistic as well as effortlessly convenient basis of treatment in the foremost healthcare body. Tinospora cordifolia is a broadly used shrub in traditional as well as Ayurvedic systems of medication throughout India. The plant consists numerous medicinal properties such as antioxidant, antimicrobial, anticancer activity etc. Tinospora cordifolia is a multipurpose reserve for all forms of life. The present review aims to throw light regarding the bioactive compounds and therapeutic facets of the Tinospora cordifolia.
Enzyme based biosensor for onsite detection of Chromium
Authors: Kaur Rasleen , Keshavkant S.
Published: August 2022

Environment has own permissible limit of heavy metals (HMs) in its every component (soil, water and air). Excess use of HMs overcomes this limit hence, leading to toxicity affecting the life on Earth. Due to the oxidizing property of the chromium (Cr), one of the HMs, it is widely used for a number of purposes such as manufacturing of stainless steel, in tannery industry, as cleaning agent for glassware, etc. Chromium has two main stable oxidation states; hexavalent (VI) and trivalent (III), out of which earlier is comparatively more toxic than the later form. Solubility of Cr (VI) in ground water had led to the need of designing a sensitive device which can be quite efficient in monitoring of its presence in the environment. In this review, an attempt has been made to collate information, so far available, on the use of microbial system for intake and detoxification of Cr following use of chromate reductase (CR) enzyme.
Nutrients and bioactive compounds of Pleurotus ostreatus mushroom
Authors: Sen Pingla , Kosre Anjali , Koreti Deepali , Chandrawansi Nagendra Kumar , Jadhav Shailesh Kumar
Published: August 2022

Mushrooms have bioactive compounds such as phenol compounds, terpenes, steroids, polysaccharides and vitamins etc. performing various biological activities can benefit the health.Pleurotus sp. is popularly cultivated edible mushrooms worldwide. It contains macronutrient and micronutrient along with certain bioactive compounds hic are of medicinal importance. The compounds isolated from mushroom are of great significance in pharmaceutical, cosmetic, neutraceuticals as well as for therapeutics purpose and prevention and treatment of diseases through their immunomodulatory property.
The optimization and selection of venture capital incentive policies under uncertain condition
Authors: Yan Wenjun , Zhang Jiaqi , Xu Jianing , He Haonan , Wang Shanyong ,   School of Economics & Management, Chang’an University, Xi’an 710054, China,   School of Public Affairs, University of Science and Technology of China, Hefei 230026, China
Published: August 2022

Venture capital is crucial innovation capital. A venture capital option game model is constructed to obtain an incentive strategy that drives venture capital to actively allocate resources to support innovation based on risk subsidies and tax incentives. Moreover, the implementation effect of venture capital incentive policies under the value-uncertain condition of the entrepreneurial enterprise is studied. The results illustrate that when the uncertainty of the value of the entrepreneurial enterprise is less than the threshold, the tax preference policy is more effective in accelerating the investment decision-making of venture capital institutions. In contrast, the two policies have identical effects. When the uncertainty of the value of the entrepreneurial enterprise is less than the threshold, the risk subsidy policy has a better effect on increasing the investment scale of venture capital institutions, while the two policies have the same effect.
Sparse linear discriminant analysis via ℓ0 constraint
Authors: Yin Qi , Shu Lei ,   Department of Statistics and Finance, School of Management, University of Science and Technology of China, Hefei 230026, China
Published: August 2022

We consider the problem of interpretable classification in a high-dimensional setting, where the number of features is extremely large and the number of observations is limited. This setting has been extensively studied in the chemometric literature and has recently become pervasive in the biological and medical literature. Linear discriminant analysis (LDA) is a canonical approach for solving this problem. However, in the case of high dimensions, LDA is unsuitable for two reasons. First, the standard estimate of the within-class covariance matrix is singular; therefore, the usual discriminant rule cannot be applied. Second, when \begin{document}$p$\end{document} is large, it is difficult to interpret the classification rules obtained from LDA because \begin{document}$p$\end{document} features are involved. In this setting, motivated by the success of the primal-dual active set algorithm for best subset selection, we propose a method for sparse linear discriminant analysis via \begin{document}$\ell_0$\end{document} constraint, which imposes a sparsity criterion when performing linear discriminant analysis, allowing classification and feature selection to be performed simultaneously. Numerical results on synthetic and real data suggest that our method obtains competitive results compared with existing alternative methods.
Big Data Quality - A Survey Paper to Attain Data Quality
Authors: Y. Anusha , R. Visalakshi , K. Srinivas
Published: August 2022

Data, collection of data, and assessing the quality of data are crucial aspects. The World Federation of Hemophilia (WFH) collects data from its members, which helps it to keep track of the health details of the people. In such cases, if the available current data is accurate then the results will be correct. Ensuring high-quality data and assessing the quality of the data is also important in health systems. Quality data has a few measures to be checked. Timeliness, relevance, understandability, completeness, and reliability are some of the main measures of data quality. After reviewing data quality assessment methods, we found that institutions and health organizations review their data frequently to achieve data quality. Huge data with massive quantity and complicated nature is generally not structured well and is in transliterated language and it becomes an issue to deal with this big data. Big data comprises a 4V model which means huge volume, velocity, variety, and veracity. Huge volume is a chunk of gathered data that contains different formats like graphics, videos, text, images, etc. Data from all these areas will be collected and assessed. We will be working with the health databases and their outcomes. There are many limitations to assessing data quality; it is because of incomplete definitions of data quality and its measures. In the future, research can be done to improve data quality and its attributes. We can increase efforts to improvise the data collection process and define the attributes more clearly and precisely.
Silk: history, obtaining, structure and properties of an old material in the development of new technologies
Authors: Silva Pugina Roberta , Almeida Caiut José Maurício
Published: August 2022

The silk produced in the Bombyx mori’ glands and used in the preparation of the cocoons has been employed in the textile industry millennia ago in fabric production. These cocoons are composed mainly of fibroin (SF, Silk Fibroin), a fibrous protein that presents unique mechanical properties, in addition to being a biocompatible, biodegradable and low-cost source. This protein can be extracted from these cocoons by being processed in aqueous medium and used to obtain the most diverse materials for different applications, such as biomaterials development as body implants and in the composition of the scaffolds for tissue engineering, moreover to photonic devices as sensors, waveguides and lasers.
Comparison between three decellularization protocol whit SDS in swine esophagus: a future option in veterinary medicine
Authors: Alves dos Santos Anna Julia , Jacintho Delgado Ana Lídia , Miglino Maria Angélica , Maia de Souza Karoline
Published: August 2022

Disease such as megaesophagus and esophagitis does not have a cure. Esophagitis has treatments depending on it’s degree, while megaesophagus has a palliative treatment, which can be recommended euthanasia in cases of a poor prognosis, cases that the esophagus transplant could be at use, although it is not described in literature. In this perspective the regenerative medicine have techniques of a bioengineering of tissues, creating a minor immune response in transplants, as it removes the organ’s genetic material, preserving the extra cellular matrix (ECM). Different protocols have been evaluated for swine esophagus decellularization, using sodium dodecyl sulphate (SDS) in concentrations 0,5%, 1,0% and 1,5% for seven days, analysing the remaining EMC integrity. It has been concluded that the material in 0,5% of SDS showed more integrity of the remaining EMC compared to the other concentrations, demonstrating that it is the best biological scaffold for future medical applications.
Innovation projects at the University-Pharmaceutical Industry interface: challenges and opportunities
Authors: Miziara Barboza Ferreira Leonardo , Miziara Barboza Ferreira Lincoln , Angela Sant Anna Carvalho Jamily , Yun Cha Paulo , Figueiredo Oliveira Ana Beatriz
Published: August 2022

COVID-19 pandemic accelerated the digital transformation of pharmaceutical R&D. This paper aimed to diagnose some key aspects of University-Pharmaceutical Industry (U-Pharma) partnerships in Brazil that should be addressed in digital platforms to enable the creation of innovative solutions to COVID-19. A qualitative research was applied through an online guiding questionnaire to identify the main points that are considered as opportunities or challenges by the parties involved in the University-Pharmaceutical Industry interface. The responses were processed using content analysis to raise common themes. Further, in-depth interviews were performed to evaluate the subjective perception of these themes. The results of the questionnaire showed the topics bureaucracy, partnership, and agility as the most relevant. The in-depth interviews showed the subjective perception of these themes. The joint analysis of the results showed that in addition to problems related to project management processes, issues that involve the human dimension, such as pro-executive behavior and communication skills, are also extremely relevant to the success of U-Pharma projects. The development of digital solutions for Knowledge Management of innovative projects of U-Pharma collaborations should take into consideration both the project and human dimensions. It is recommended that Project and People Management should be integrated into digital platforms.
Bacteriological assessment of stethoscope used by health care personnel in attat hospital, SNNP, Gurage Zone, Ethiopia
Authors: Salile Tamirat
Published: August 2022

Abstract
Stethoscope has always been a part of the physicians’ basic tool for examining patients. Universal use of stethoscope for examination of patients by health care personnel makes it a potential source for spread of nosocomial infection. This study was designed to assess the potential for bacterial transmission by stethoscopes used by different health-care workers in Attat hospital. A cross sectional study was conducted from April to June 2018 in university of Wolkite, department of biotechnology and biology in molecular laboratory. During the study period there were a total of 26 stethoscopes from health professionals who had direct contact with patients are collected. Sample was collected by sterile cotton-tipped applicator moistened in a sterile solution of physiologic saline (0.85% sodium chloride) that was used to swab the entire surface of the diaphragm of the stethoscope and then inoculated into macconkey agar, tryptone soya agar and blood agar media. 18(69.2%) stethoscopes out of total collected stethoscopes had bacterial growth and 12 bacterial isolates were selected and characterized to genus level. Isolates include staphylococcus aureus(37.5%), coagulase negative staphylococci (28.12%), Streptococcussp. (21.88%), and Bacillus sp.(12.5%). All isolates were susceptible to the co-trimoxazole and ciprofloxacine, while resistant to cifoxitine. They showed intermediate growth against vancomycine. All except streptococcus were found resistant against penicillin.  Both S. aureus and CoNS were sensitive to the chloramphenicol; Streptococcus was intermediate while bacillus was resistant to the chloramphenicol All stethoscopes (42.2%) that had never cleaned and last cleaned a week agowere highly contaminated while lower levels of contamination (27%) were found on those cleaned several times a day and cleaned between each patient before the examination of the patients.
Green synthesis of hydroxyapatite nanoparticles for biomedical application: a brief review
Authors: Melgar Andrea Elizabeth , Fagundes Ana Paula , Macuvele Domingos Lusitâneo Pier , Padoin Natan , Soares Cintia , Riella Humberto Gracher
Published: August 2022

Hydroxyapatite [Ca10(PO4)6(OH)2] (HAp) is a calcium phosphate mineral of great interest in biomaterials development because it is the main component of the mineral phase of bones and teeth’s of animals and humans. HAp plays a key role in the biomedical field due to its non-toxicity, anti-inflammatory property, osteointegrity, biocompatibility, and other properties. Some of its applications in tissue engineering involve bone repair, bone augmentation, coating of implants, and fillers for bones and teeth. Besides, HAp can function as a drug delivery system due to its porous nature, which gives the nanoparticles a larger surface area. However, the use of organic templates in order to obtain HAp nanoparticles with a specific shape, morphology, size, and textural properties makes it impractical from an ecological and cost-effective standpoint. Throughout the last decade, several attempts to improve synthetic procedures have been under development. Recently, special attention has been given to the application of plant extracts as substitutes for organic templates, though they are not extensively reported in literature. Therefore, this brief review aims to examine the existing routes for synthesis of hydroxyapatite nanoparticles. Then the focus shifts to an overview of greener procedures and an outlook of their benefits in biomedical applications.
The role of management accounting system and organizational culture in mediating the relationship between mutual dependency and environmental uncertainty
Authors: Hardi Hardi , Budiyanto Budiyanto , Agustedi Agustedi
Published: August 2022

This study aimed to develop a conceptual model of the mediating role of management accounting system (Broadscope) and organizational culture on the influence of mutual dependency and environmental uncertainty on managerial performance. The sample was 126 managers of Swamitra Palm Oil Plantation in Riau. The entire population was sampled. The data were processed using Structural Equation Modeling Partial Least Square (SEM PLS). The findings in this study are mutual dependency and environmental uncertainty have a positive influence on managerial performance, organizational culture mediates the influence of environmental uncertainty on managerial performance, meanwhile management accounting system (Broadscope) does not mediate the influence of mutual dependency on managerial performance.
Classifying cubic symmetric graphs of order $18 p^2$
Authors: Alaeiyan Mehdi , Hosseinipoor Mohammad Kazem , Akbarizadeh Masoumeh
Published: August 2022

A $s$-arc in a graph is an ordered $(s+1)$-tuple $(v_{0}, v_{1}, \cdots, v_{s-1}, v_{s})$ of vertices such that $v_{i-1}$ is adjacent to $v_{i}$ for $1\leq i \leq s$ and $v_{i-1}\neq v_{i+1}$ for $1\leq i < s$. A graph $X$ is called $s$-regular if its automorphism group acts regularly on the set of its $s$-arcs. In this paper, we classify all connected cubic $s$-regular graphs of order $18p^2$ for each $s\geq1$ and each prime $p$.
Plant regeneration through somatic embryogenesis of pseudostem callus culture response in In-vitro condition of palmarosa grass (Cymbopogon martinii) with special reference to hardening and pot culture
Authors: Das Somnath , Ghosh Parthadeb
Published: August 2022

This study successfully achieved somatic embryogenesis and plant regeneration from callus culture of the plant Cymbopogon martinii (Palmarosa Grass). The ability of medicinally significant palmarosa grass to regenerate through somatic embryogenesis of pseudostem callus culture has been investigated using hardening and pot culture. Cymbopogon martinii pseudostem explants were employed, and the Murashige and Skoog medium (MS basal media) was added with 2,4-dichlorophenoxyacetic acid (2,4-D). In MS basal medium supplemented with 2,4-D (3 mg/1it.)+ 6-Benzyl Adenine Purine (BAP) (1 mg/1it.), plant regeneration through embryogenesis occurred. In MS baseline media supplemented with α-Naphthelene Acetic Acid (NAA) (2 mg/1it.)+BAP (0.01 mg/1it.) and NAA (1.5 mg/1it.)+BAP (0.01 mg/1it.), whole plantlets were formed. Microplant for hardening was transplanted with well-developed rootlets from in-vitro to in-vivo. Sand, soil, and cow dung cake were mixed in a 1:1:1 ratio for the potting mixture, which was then exposed to light, temperature, and humidity. The results demonstrate that MS medium enriched with 1 mg/lit. of 2,4-D allowed for the greatest induction of callus and proliferation. In the current investigation, it was discovered that 2,4-D supplementation to MS medium was successful in triggering Cymbopogon martinii's callus response.
Review on Phyto-chemistry & pharmacological activity of Melia azedarach
Authors: Kar Durgesh Ranjan , Ghosh Priojit , Suresh Padilam , Chandra Shaibal , Paul Dhrubakishore
Published: August 2022

Medicinal plants as essential additives in foods, beverages, and medications have been a part of human culture since the dawn of time. Medicinal plants' nutritional, pharmacological, biological, and toxicological characteristics have numerous applications in numerous industries. Nowadays, most people rely on complementary and alternative therapies to treat various illnesses derived from natural sources. Melia azedarach is one of the plants (Meliaceae family) grown in numerous Indian states. The entire plant or its parts (leaves, stem and roots) have medicinal characteristics and have been used by native and tribal people in various parts of India for a very long time. This plant has traditionally been used to cure various conditions, including piles, itching, asthma, leprosy, and cough. The current study includes a comprehensive analysis of its systematic botanical position, phytochemical analysis, research on the plant's pharmacological activity, and medicinal applications.
Vegetation Community Characteristics and diversity in different phases of mining at Charhi and Kuju coal mining areas, Jharkhand, India
Authors: Biswas Deep Shubhra , Prathap Amudala , Chakraborty Sukalyan
Published: August 2022

The increase in the energy requirement of a country shows its economic advancement. Coal mining activity has increased considerably to compensate for the increased energy requirements. As a result, open-cast coal mining methods induced a drastic change in land use and seriously jeopardized the sustainability of the ecosystem. Once disrupted by open-cast or underground mining, the condition of the land cannot be entirely recovered, making it a non-renewable asset to the environment and support of human life. An attempt was made to study the existing flora of the different zones (operating, abandoned, control) of Charhi and Kuju Coal mining area, Jharkhand, India. From 2015 to 2018,173 species belonging to 75 families of angiosperms, terrestrial and aquatic ferns have been reported and identified so far from this study area. The most dominant family is Poaceae with the maximum number of species in the area, where mining has not yet been done. This paper's findings would help assess the dominant species in this area, which can be used for reclamation of the abandoned mining areas.
El probiótico Bacillus clausii es un tratamiento eficaz de la diarrea aguda en niño
Authors: Perez Marcos III , Greifenberg Dorothea
Published: August 2022

Una revisión sistemática y un metaanálisis confirman que el probiótico Bacillus clausii es un tratamiento eficaz para la diarrea aguda en la infancia. Acorta la duración de la diarrea y la hospitalización asociada. Nuevos estudios arrojan luz sobre los mecanismos subyacentes a estos efectos beneficiosos.
A Bacillus clausii probiotikum hatékony az akut hasmenés kezelésére gyermekek esetén
Authors: Perez Marcos III , Greifenberg Dorothea M.
Published: August 2022

Egy szisztematikus áttekintés és metaanalízis megerősíti, hogy a Bacillus clausii probiotikum hatékony a gyermekkori akut hasmenés kezelésére. Lerövidíti a hasmenés és a kapcsolódó kórházi kezelés időtartamát.
Los probióticos pueden prevenir los síntomas gastrointestinales inducidos por los fármacos
Authors: Plomer Manuel , Perez Marcos III
Published: August 2022

Los probióticos, como el Bacillus clausii, reducen la aparición de efectos secundarios gastrointestinales de medicamentos de uso común, como los antibióticos y los inhibidores de la bomba de protones, en ensayos aleatorizados controlados con placebo. Su uso puede hacer que los esquemas de erradicación de Helicobacter pylori sean más tolerables.
Esenciální fosfolipidy u steatózy jater
Authors: Minarik Peter , Koscova Eva
Published: August 2022

Játra jsou důležitým orgánem metabolismu a imunitního systému. Nadměrný příjem sacharidů nebo nadměrná konzumace alkoholu mohou vyvolat zánětlivé procesy a vést k rozvoji steatózy jater. Přehled literatury vycházející z 25 studií vykázal pozitivní účinky po použití esenciálních fosfolipidů.
Niezbędne fosfolipidy w chorobach stłuszczeniowych wątroby
Authors: Minarik Peter , Koscova Eva
Published: August 2022

Wątroba jest ważnym narządem metabolizmu i układu odpornościowego. Nadmierna podaż węglowodanów lub nadmierne spożywanie alkoholu może wywoływać procesy zapalne i prowadzić do rozwoju choroby stłuszczeniowej wątroby. Przegląd literatury oparty na 25 badaniach wykazał pozytywne efekty stosowania fosfolipidów niezbędnych.
Esenciálne fosfolipidy pri tukových ochoreniach pečene
Authors: Minarik Peter , Koscova Eva
Published: August 2022

Pečeň je dôležitý orgán pre metabolizmus a imunitný systém. Nadbytok sacharidov alebo nadmerná konzumácia alkoholu môžu spustiť zápalové procesy a viesť k rozvoju tukového ochorenia pečene. Prehľad literatúry na základe 25 štúdií ukázal pozitívne účinky po používaní esenciálnych fosfolipidov.
O acetonido de triancinolona intranasal melhora eficazmente os sintomas nasais e a qualidade de vida em pacientes com rinite alérgica perene
Authors: Amessou Mohamed , Leshcheva Elizaveta , Maslakov Aleksandr , Venkataraman Palak
Published: August 2022

A rinite alérgica é um problema comum que apresenta uma prevalência crescente. Duas publicações recentes evidenciam que o acetonido de triancinolona intranasal é um tratamento eficaz que melhora progressivamente os sintomas nasais e a qualidade de vida em pacientes adultos com rinite alérgica perene.
Compreender melhor a “cefaleia do século XXI” por meio de dados do mundo real
Authors: Constantin Luminita , Eberlin Marion , Turudic Iva Igracki , Michel Martin C.
Published: August 2022

Em todo o mundo, a cefaleia é uma das principais causas de limitações na vida diária e/ou de inaptidão para o trabalho. 50% das pessoas que sofrem de cefaleias nunca consultam um médico e, em vez disso, recorrem à automedicação. Um consenso de especialistas publicado recentemente investigou este fenómeno com mais pormenor e associou-o mesmo a um conceito científico chamado “a cefaleia do século XXI”.
Mai buna înțelegere a „Migrenei secolului 21” pe baza datelor din lumea reală
Authors: Constantin Luminita , Eberlin Marion , Turudic Iva Igracki , Michel Martin C.
Published: August 2022

La nivel mondial, migrena este una dintre principalele cauze ale limitărilor vieții de zi cu zi și/sau incapacității de a munci. 50% dintre cei care suferă de aceasta nu au consultat niciodată un medic, apelând în schimb la automedicație. O opinie consensuală a experților recent publicată a investigat mai în detaliu acest fenomen și l-a asociat unui concept științific denumit „migrena secolului 21”.
Update zur antibiotischen Behandlung unkomplizierter Hautabszesse
Authors: Sethmann Annette
Published: August 2022

Kutane Abszesse werden häufig durch S. aureus hervorgerufen. Wichtigste therapeutische Maßnahme ist die Drainage der Eiteransammlung. Obwohl der klinische Nutzen einer zusätzlichen oralen Antibiotikagabe belegt ist, wird sie angesichts steigender Resistenzen zunehmend kritisch gesehen. Vor diesem Hintergrund ist es interessant, dass für die bei Abszessen seit Langem lokal eingesetzten Ammoniumbituminosulfonate eine antimikrobielle Wirkung auch gegen MRSA nachgewiesen wurde.
A novel combination reduces objective measures and subjective stress perception
Authors: Noah Lionel
Published: August 2022

Reducing harmful stress is a key challenge to preserve well-being. A recent, randomized, double-blind, placebo-controlled study in moderately stressed healthy adults (Clinicaltrials.gov: NCT03262376; 25/0817) demonstrates beneficial effects of a combination of magnesium, B vitamins (B6, B9, B12) and rhodiola and green tea extracts against objective and subjective indicators of stress. It was more effective than either extract alone.
Eine neue Kombination reduziert objektive Stressmaße und subjektives Stressempfinden
Authors: Noah Lionel
Published: August 2022

Der Abbau von schädlichem Stress ist eine zentrale Herausforderung für die Erhaltung des Wohlbefindens. Eine kürzlich durchgeführte randomisierte, doppelblinde, placebokontrollierte Studie mit mäßig gestressten gesunden Erwachsenen (Clinicaltrials.gov: NCT03262376; 25/0817) zeigt die positiven Auswirkungen einer Kombination aus Magnesium, B-Vitaminen (B6, B9, B12) sowie Rhodiola und grünem Tee auf objektive und subjektive Stressindikatoren. Die Kombination war wirksamer als die jeweiligen Extrakte allein.
Ένας καινοτόμος συνδυασμός μειώνει τους αντικειμενικούς δείκτες και την υποκειμενική αντίληψη των επιπέδων του στρες
Authors: Noah Lionel
Published: August 2022

Η μείωση του επιβλαβούς στρες αποτελεί βασική πρόκληση για τη διατήρηση της ευεξίας. Μια πρόσφατη, τυχαιοποιημένη, διπλά τυφλή, ελεγχόμενη με εικονικό φάρμακο μελέτη σε υγιείς ενήλικες με μέτριο επίπεδο στρες (Clinicaltrials.gov: NCT03262376; 25/0817) δείχνει ωφέλιμες επιδράσεις ενός συνδυασμού μαγνησίου, βιταμινών B (B6, B9, B12) και εκχυλισμάτων ροδιόλας και πράσινου τσαγιού επί των αντικειμενικών και υποκειμενικών δεικτών του στρες. Ο συνδυασμός ήταν πιο αποτελεσματικός από ό,τι το καθένα από τα εκχυλίσματα μόνο του.
Una combinación novedosa reduce las medidas objetivas y la percepción subjetiva del estrés
Authors: Noah Lionel
Published: August 2022

La reducción del estrés nocivo es un reto clave para preservar el bienestar. Un estudio reciente, aleatorizado, doble ciego y controlado con placebo realizado en personas adultas sanas con un nivel de estrés moderado (Clinicaltrials.gov: NCT03262376; 25/0817) ha demostrado que los efectos beneficiosos de una combinación de magnesio, vitaminas del grupo B (B6, B9, B12), extractos de rodiola y té verde en los indicadores objetivos y subjetivos del estrés fueron más eficaces que con cualquiera de los dos extractos por separado.
Egy újszerű kombináció csökkenti az objektív méréseket és a szubjektív stresszérzékelést
Authors: Noah Lionel
Published: August 2022

Egy nemrégiben végzett, randomizált, kettős vak, placebo-kontrollos közepesen stresszes vizsgálat, egészséges felnőtteken (Klinikai vizsgálatok, clinictrials.gov: NCT03262376; 25/0817) bemutatja a magnézium, a B-vitaminok (B6, B9, B12), valamint a rhodiola és zöld tea kivonatok jótékony hatását a stressz objektív és szubjektív mutatóival szemben. Hatékonyabb volt, mint bármelyik kivonat önmagában.
Abdominal ağrının tedavisi için kılavuz öneriler (İrritabl Bağırsak Sendromu’nda)
Authors: Weiser Thomas
Published: August 2022

Abdominal ağrı yaygındır ve yaşam kalitesini olumsuz etkiler. Dünya çapında birçok uzman cemiyeti, İrritabl Bağırsak Sendromu’nun tedavisine ilişkin kılavuzlar oluşturmuştur ve bunların tümü, abdominal ağrının tedavisi için antispazmodiklerden bahsetmektedir. Bununla birlikte, tam olarak hangi etken maddelerin kullanıldığı, mevcut tedavi seçeneklerine bağlıdır. Pek çok kılavuzun açıkça Hiyosin Butilbromür ve nane yağını önermesi dikkate değerdir, oysa analjezik kullanımı bir seçenek değildir.