bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring of immune mechanisms of pathogenesis and efficiency of immune therapy in children with various phenotypes of bronchial asthma
Authors: Prosekova E V , Sitdikova T S , Zhdanova O L
Published: June 2020

Background. Peculiarities of the disease and effectiveness of therapy depend on changes in availability and functions of effector immunocompetent cells and cytokine profile. Purpose. To study the peculiarities of immune pathogenetic mechanisms of virus-induced and allergen-induced bronchial asthma phenotypes in children in order to justify the use of immune therapy and to analyze it’s effectiveness. Materials and methods. We have performed an integrated assessment of immunological parameters in 120 children at the age of 3-11 y.o. with virus-induced and allergen-induced phenotypes of bronchial asthma (BA) and in 30 healthy children. Withdrawal criteria: severe BA, immune therapy during preceding 6 months. We used flow flow cytometer COULTER EPICS XL (Beckman Coulter Inc.) for identification of venous blood cells, CYTOKINE-STIMUL-BEST sets (Vektor-Best JSC, Novosibirsk) for levels of spontaneous and mitogen-induced production of cytokines identification. The immunological effectiveness of treatment was analyzed in the open parallel prospective study using random sampling technique in subgroups on the basis of treatment regimen. Statistical data processing was performed by «Statistica 10» program with critical significance level p
Irrigational therapy in complex treatment of patients with allergic rhinitis
Authors: Svistushkin V M , Sinkov E V
Published: June 2020

Today allergic rhinitis is one of the most widespread diseases of a cavity of a nose. Irrigational therapy promotes considerable reduction of allergens at surfaces of a mucous membrane of upper airways and leads consumption of medicines at reduction in patients with allergic rhinitis.
Peptides in the composition of Laennec that show antiviral effects in the therapy of atopic dermatitis and herpes infection
Authors: Torshin I Yu , Gromova O A , Dibrova E A , Gromov A N , Nazarenko O A
Published: June 2020

A characteristic feature of atopic dermatitis is herpes infection, which necessitates application of antiviral therapy. The analysis of the peptide composition of Laennec drug by de novo mass spectrometric sequencing allowed us to identify over 10 peptides, characterized by potential antiviral effect at all stages of the viral life cycle. Laennec’s peptides can inhibit viral activation (inhibition of protein HCFC1), fusion of the viral envelope with the plasma membrane in the step of the host cell virus infection (inhibition of protein CD4), virus replication (inhibition of protein CTBP1), maturing of virion (inhibition of proteins CRM1, VPS4B, TPR, proline isomerase), budding of the viral particles from the cell membrane (inhibition of the NEDD4 protein). Laennek therapy in complex treatment of patients with atopic dermatitis and herpes virus infection can be substantiated by its pharmacologic activities including antiviral effect.
IgE and IgG4-autoantibodies in patients with bronchial asthma
Authors: Gervazieva V B , Konishcheva A Yu , Samoilikov P V , Magarshak O O , Mazurina S A , Sveranovskaya V V
Published: June 2020

The aim. Special interest has been recently noted in the autoreactivity as one of the mechanisms of bronchial asthma (BA) pathogenesis. The purpose of the study was to determine levels of IgE- and IgG4-autoantibodies (autoAbs) to tissue antigens (Ag) - keratin, collagen III and VI types, myosin and elastin using adapted ELISA method in blood serum of 88 patients with bronchial asthma (BA) of different severity and clinical course. Results. We determined that in patients with BA the quantitative levels and frequency of Ig-EautoAbs to all those Ags were significantly enhanced and were more prominent in severe (59-81%) than in mild and moderate BA (p
The modern view of the role of innate and adaptive immunity in bronchial asthma
Authors: Galitskaya M A , Kurbacheva O M
Published: June 2020

This article provides an overview of international data about immunological aspects of the pathophysiology of bronchial asthma (BA). The relationship between innate and adaptive immunity, as well as participation of various interleukins and cells in the development of inflammation in BA are presented. The possibility of the creation of new therapeutic molecules for the treatment of BA is substantiated.
PENGARUH HARGA MINYAK DUNIA TERHADAP PERTUMBUHAN EKONOMI, INFLASI, DAN PENGANGGURAN DI INDONESIA
Authors: Purnomo Sodik Dwi , Istiqomah Istiqomah , Badriah Lilis Siti
Published: June 2020

The purpose of this research is to analyze the influence of oil prices fluctuations to Indonesia macroeconomics that is economic growth, inflation, and unemployment from 1988 to 2018. The data analysis technique uses Vector Autoregressive (VAR). The result showed that oil price fluctuations in the amount of one standard deviation will gives a positive influence to economic growth, inflation rate, and unemployment which each has 0,001 percent, 0,001 percent, and 0,002 percent.Keyword : World Oil Prices, Economic Growth, Inflation, and Unemployment Abstrak Tujuan dari penelitian ini adalah untuk mengetahui bagaimana pengaruh fluktuasi harga minyak dunia terhadap variabel makroekonomi Indonesia yaitu pertumbuhan ekonomi, inflasi, dan angka pengangguran dari tahun 1988 sampai dengan 2018. Teknik analisis data menggunaan Vector Autoregression (VAR). Hasil analisis menunjukkan bahwa guncangan yang terjadi pada fluktuasi harga minyak dunia sebesar satu standar deviasi akan memberikan pengaruh positif terhadap pertumbuhan ekonomi, inflasi serta pengangguran yaitu masing-masing sebesar 0,001 persen, 0,001 persen, dan 0,002 persen.Kata Kunci : Harga Minyak Dunia, Pertumbuhan Ekonomi, Inflasi, dan Pengangguran
Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota
Authors: Durganaudu Hanusha , Kunasegaran Thubasni , Ramadas Amutha
Published: June 2020

Diet therapy is often the first-line approach in prevention and management of type 2 diabetes mellitus (T2DM). Adoption of low glycaemic index (GI) diet one of the recent dietary strategies to modulate glycaemic response in individuals with T2DM. Generally, diet has strong influence on the gut microbiota, which recently have been found to be associated with insulin resistance and the inflammatory response in diabetes. The possible modulation of the gut microbiota with dietary intervention is a topic of emerging interest, with limited evidence among T2DM population. In this review, we have narrated the available evidence and discussed the current knowledge about diet manipulation associated with dietary GI in order to shape the gut microbiota. As a conclusion, we have pointed out several key research directions that may have helpful impact on diet interventions with modulation of gut microbiota on the pathogenesis and therapeutic implications in T2DM.
ПОЄДНАННЯ РИМО-ГОТСЬКОЇ ТА РИМО-ІРЛАНДСЬКОЇ ТРАДИЦІЙ У МУЗИЧНІЙ КУЛЬТУРІ КАРОЛІНГСЬКОГО ВІДРОДЖЕННЯ
Authors: Рябокінь Аліна
Published: June 2020

У статті йдеться про переплетення двох культур на теріторіі континентальної Європи після варварського завоювання –традицій музичного виховання Вестготської Іспанії та досягнень в освіті ірладских монастирів, що були впроваджені Алкуїн Йоркським в Імперії Карла Великого. Музика у ті часи розглядалася як вища математична дисципліна, що була під силу лише найрозумнішим і найздібнішим учням. Автор статті аналізує публікації з цієї проблематики та визначає ту площину, яка на сьогоднішній день мало вивчена. Особливу увагу привернуто до обов΄язкового характеру музичної освіти у ранньосередньовічних європейських державах, на значення музики серед «семи вільних мистецтв», своєчасності появи шкіл-метріз для підготовки професійних церковних півчих, зародження меси як центральної частини богослужіння, ускладнення музичного малюнку християнських піснеспівів. Акцент зроблено на педагогічних ідеях Ісидора Севільського і Алкуїна Йоркського, методах заохочення та покарання, формах організації ними навчально-виховного процесу в єпископальних і монастирських школах раннього Середньовіччя, що стало фундаментом виникнення університетів в Західній Евпропі. Автор статті расскриває середньовічне розуміння музики як науки і як мистецтва, її складових частин: органіки, гармоніки й ритміки, у цитованих джерелах тієї далекої епохи аналізує відомості про інструменти, на яких грали учні монастирських і єпископальних шкіл на третьому рівні навчання, виділені ті семестри, коли вони займалися винятково музикою.
Studi Penangkapan Ayam Hutan Merah di Kabupaten Kaur Bengkulu
Authors: Suhadi Miki
Published: June 2020

The objective of this research was to gather information about capturing techniques used by the local communities in Kaur District. Respondents were chosen by using snowball sampling method. Variables observed were equipment used by respondents, the time and location of capturing red jungle fowl. The result showed that the equipment used by the respondents are food supplies (rice and water), weapons (machetes, knives, matches), and clothing (hats , jackets, trousers, raincoats) and red jungle fowl hooks, nets, racit, sangkek and bags. Most of respondents chose the location of luring jungle fowl in the plantation area.

Keywords: catching, equipment, red jungle fowl
Pengaruh Pemberian Susu Afkir terhadap Konsumsi Pakan, Pertambahan Bobot Badan Harian dan Konversi Pakan Broiler
Authors: Angsori Muhammad , Wati Novi Eka , Wicaksana Kunaifi
Published: June 2020

The objective of this experiment was to determine the effect of rejecting milk on drinking water on feed intake, daily body weight gain and feed conversion of broilers. The material of this study included 200 broilers aged 14 days given P0= drinking water treatment without giving an reject milk and P1= drinking water with the addition of rejected milk. Chickens were treated for 14 days and fed with PK= 22.0-23.0%, Fat= 5.0%, Calcium= 0.9%, Phospor= 0.6%, ME= 3050-3150 Kcal/Kg. In conclusion, rejected milk in drinking water has a significant effect on daily body weight gain, but does not significantly effect on feed intake and feed conversion. The daily body weight gain of P1 was higher than P0.

Keywords: broilers, daily weight gain, feed intake, feed conversion ratio, rejected dairy milk
The Management Skills of SALL Managers
Authors: Gardner David , Miller Lindsay
Published: June 2020

This paper looks at the management skills of SALL managers. It is based on data collected using quantitative and qualitative instruments with six SALL managers in tertiary contexts in Hong Kong. With reference to the literature in the field of management, the paper reviews the data in terms of identifiable management skills. This provides a picture of the skills possessed by these managers and also identifies gaps in their skill-sets. The paper provides a checklist of skills relevant to SALL management which individual managers may find useful, and also discusses the 4 key management areas of leadership, scope, expectations and evaluation.
Looking Out for English
Authors: Tomlinson Brian
Published: June 2020

Coursebook activities tend to neglect three vital prerequisites for effective language acquisition i.e. language experience, language discovery and language use. They tend to focus on providing instruction, exemplification and practice in the classroom, and they do very little to encourage learners to achieve language experience, discovery and use outside the classroom. In this article I propose ‘new ideas’ for materials which help learners to gain language experience, language discovery and language use both inside and outside the classroom.
Accessing the Self in Self-Access Learning: Emotions and Feelings in Language Advising
Authors: Tassinari Maria Giovanna , Ciekanski Maud
Published: June 2020

The importance of the affective dimension and the role of beliefs, self-efficacy and learners’ voices in language learning are recognized in the literature (Arnold, 1999; Brewer, 2006; Ogasa, 2010). Although emotions and feelings seem to play an important role in self-directed language learning (Bown & White, 2010; Candas & Eneau, 2010), little is still known about how to support the affective dimension throughout the self-directed learning process (Aoki, 1999). Clearly, the cognitive and the metacognitive, the subjective and affective dimensions of learning need to be addressed, in a self-access centre, in order to support learners on their road to autonomy.

Language advising provides the appropriate arena for this. Within the professional and interpersonal relationship between advisors and learners (Ciekanski, 2007), it is easier to reflect on the affective implications of learning and to help learners to cope with them. Ongoing research into emotions and feelings in advising contexts shows that affect and subjectivity occupy a large proportion of learners’ (and advisors’) discourse. This paper makes a case for integrating reflection on the affective and subjective dimensions of learning, both in the research and in the practice of language advising.
Medics on the Move South Africa: Access to Medical Words
Authors: Van de Poel Kris , Fourie Christine , Seberechts Karen
Published: June 2020

South African medical students who are Cuban-trained and therefore Spanish- speaking, on their return to South Africa need to learn medical vocabulary, terminology, and appropriate interactional discourse in the two major languages of English and Afrikaans, in order to be able to practise professional medicine effectively and efficiently. Indeed, their language problems are further compounded by differences in medical equipment and in medical practices between Cuba and South Africa. To meet these particular students’ needs and provide a communication support tool, the concept of a paper-based pocket-size multi-lingual illustrated dictionary was introduced as an additional component in a blended learning approach, to complement online materials called MoM-SA. The dictionary, to which students are invited to add material, has word lists in English, Afrikaans and Spanish, and offers links to the online materials. Students can add terminology, translations into other African languages and images, so that the dictionary grows and reflects the everyday needs of the students, who, at the same time, become co-owners of the dictionary; thus, process has become content and, as a result, learner motivation has increased.
Using CBT with Anxious Language Learners: The Potential Role of the Learning Advisor
Authors: Curry Neil
Published: June 2020

Foreign Language Anxiety (FLA) can be a crippling condition for many students, preventing them from taking an active part in the classroom, and also retarding their L2 use in wider communicative situations. Providing learners with the tools to overcome anxiety on an individual basis is an area which needs further investigation. Cognitive Behaviour Therapy (CBT) is a widespread counselling practice used to treat anxieties. It shares similarities with some techniques employed in Advising in Language Learning (ALL) for helping students with language goals, and it is worthwhile investigating and raising awareness of how it can be used for FLA. The article describes major characteristics of FLA and also CBT, and then describes four functions which CBT and ALL share: goal-setting, guided discovery, Socratic questioning and use of reflection. Preliminary research also demonstrates how some of the practices associated with CBT could be applied by Learning Advisors to help students to overcome FLA.
Peran Guru Kelas Dalam Meningkatkan Pemahaman Siswa Pada Pembelajaran IPA Melalui Pembelajaran Berbasis Etnosains
Authors: Wati Senja
Published: June 2020

Purpose of the study: Guru merupakan tenaga pendidik yang prosfesional. Sebagai seorang tenaga yang profesional guru harus mampu menjadi fasilitator yang baik didalam kelas. Penelitian ini peran guru dalam meningkatkan pembelajaran IPA melalui pembelajaran berbasis Etnosains Methodology: Penelitian ini menggunakan metode eksperimen. Sumber data  dalam penelitian ini yaitu kelas 5A dan 5B yang terdiri dari Kelas 5A berjumlah 25 orang yang terdiri dari 10 laki-laki dan 15 orang perempuan. Sedangkan kelas 5B berjumlah 24 orang yang terdiri dari 12 orang laki-laki dan 12 orang perempuan Main Findings: Hasil dari penelitian ini menunjukkan bahwa terjadi peningkatan pemahan siswa pada materi organ pernapasan hewan dan fungsinyya secara signifikan pada kelas ekperimen setelah pembelajaran dilakukan berbasis Etnosains. Novelty/Originality of this study: penelitian ini memiliki keterbaruan pada bidang pembelajaran yang efektif dan efisin menggunakan basis Etnosains pada pembelajaran IPA disekolah dasar.
ERRATUM
Authors: Ware Brenton R. , Brown Grace E. , Soldatow Valerie Y. , LeCluyse Edward L. , Khetani Salman R.
Published: June 2020

Testing drugs in isogenic rodent strains to satisfy regulatory requirements is insufficient for derisking organ toxicity in genetically diverse human populations; in contrast, advances in mouse genetics can help mitigate these limitations. Compared to the expensive and slower in vivo
testing, in vitro cultures enable the testing of large compound libraries toward prioritizing lead compounds and selecting an animal model with human-like response to a compound. In the case of the liver, a leading cause of drug attrition, isolated primary mouse hepatocytes (PMHs) rapidly
decline in function within current culture platforms, which restricts their use for assessing the effects of longer-term compound exposure. Here we addressed this challenge by fabricating mouse micropatterned cocultures (mMPCC) containing PMHs and 3T3-J2 murine embryonic fibroblasts that displayed
4 weeks of functions; mMPCCs created from either C57Bl/6J or CD-1 PMHs outperformed collagen/Matrigel™ sandwich-cultured hepatocyte monocultures by ∼143-fold, 413-fold, and 10-fold for albumin secretion, urea synthesis, and cytochrome P450 activities, respectively. Such functional
longevity of mMPCCs enabled in vivo relevant comparisons across strains for CYP induction and hepatotoxicity following exposure to 14 compounds with subsequent comparison to responses in primary human hepatocytes (PHHs). In conclusion, mMPCCs display high levels of major liver functions for
several weeks and can be used to assess strain- and species-specific compound effects when used in conjunction with responses in PHHs. Ultimately, mMPCCs can be used to leverage the power of mouse genetics for characterizing subpopulations sensitive to compounds, characterizing the degree
of interindividual variability, and elucidating genetic determinants of severe hepatotoxicity in humans.
The Trend and the Pattern of Seasonal Rainfall in the Period (1993-2018) in Embu East Sub County, Kenya
Authors: Ireri Linus Mugendi
Published: June 2020

Kenya, like many countries in the world, is vulnerable to climate variability and change. The livelihood of the people in Embu East Sub-county is highly dependent on rain-fed agriculture so climatic threats affect food and animal production. Climate variability has negatively affected mixed crop-livestock production. The objective of this study was: to establish the trend in seasonal rainfall in the period (1993-2018). The study used a descriptive survey research design guided by the Sustainable Livelihood Approach (SLA) theory. A sample of 364 subjects was composed of 362 heads of farming families and 2 Agricultural Field Officers. Data was obtained through the study of rainfall records in Embu Meteorological Stations, administration of household questionnaires, and interview schedule.  The Methods of data analysis and presentation included time-series line graphs to show the trend, frequency tables, and percentages. The coefficient of variation was used to check the homogeneity of March-April-MAY and October-November-December seasons. A paired sample was used to test the hypothesis. The findings established that the rainfall trend was irregular between the years 1993-2018. The onset and the cessation of the MAM and OND varied significantly even though the MAM rainfall was on the upward trend and that of the OND was on the downward trend. The study recommends the following strategies the need to establish more rainfall stations in the study area. Policymakers should build the capacity of the farmers on how to exploit MAM fully and OND seasons and design a more efficient and interactive approach among the climate scientist-decision makers and the farmers to ensure effective communication on rainfall trends and pattern.
ЗВІТ НАЦІОНАЛЬНОЇ АКАДЕМІЇ ПЕДАГОГІЧНИХ НАУК УКРАЇНИ ПРО СТАН ВИКОРИСТАННЯ КОШТІВ НА НАУКОВУ І НАУКОВО-ТЕХНІЧНУ ДІЯЛЬНІСТЬ ТА ОТРИМАНІ РЕЗУЛЬТАТИ ЗА 2018-2019 РР.
Authors: КРЕМЕНЬ Василь Григорович
Published: June 2020

У доповіді представлено інформацію про наукову діяльність Національної академії педагогічних наук України, її підвідомчих установ та кадрового потенціалу. Наведено найважливіші наукові здобутки за 2018-2019 р. із наукового і методичного забезпечення дошкільної, загальної середньої, спеціалізованої освіти наукового спрямування, виховання дітей з різними порушеннями розвитку, професійної (професійно-технічної), фахової передвищої, вищої освіти і освіти дорослих, науково-інформаційного супроводу освітянської галузі, психологічного супроводу розвитку особистості та її самопроєктування на кожному з вікових етапів, роботу з молодими вченими тощо. Висвітлено основні показники діяльності у 2018-2019 рр. про наукові публікації вчених, прогрес в ефективності наукових досліджень, зокрема представлення у наукометричних базах даних Scopus і Web of Science Core Collection, ресурс Електронної бібліотеки НАПН України, наукові періодичні видання, співпрацю з органами державної влади та організаціями, незалежну наукову експертизу, експериментальну діяльність, підготовку здобувачів наукових ступенів доктора філософії та доктора наук, діяльність спеціалізованих вчених рад, міжнародну діяльність, науково-практичні масові заходи тощо. Окреслено виклики та ризики, які впливають на вдосконалення діяльності НАПН України, а також перспективи розвитку та переваги НАПН України. Наголошено на здатності вчених НАПН України здійснювати якісний науково-методичний супровід розвитку освіти України, її людського потенціалу.
Disentangling stimulus and response compatibility as potential sources of backward crosstalk
Authors: Rieger Tobias , Miller Jeff
Published: June 2020

In two experiments (N= 60 each), we investigated the locus of backward crosstalk effects in dual tasking. Specifically, we embedded the typical flanker task within a dual-task paradigm by assigning stimulus-response (S-R) rules to the flankers. In Experiment 1, participants were instructed to first respond to the center letter and only respond to the flanker if the center was a no-go stimulus (i.e., prioritized processing paradigm). Mapping condition was varied between-subjects to be either matched (i.e., same S-R rule for flankers as for center letters), reversed (i.e., opposite S-R rule for flankers), or neutral (i.e., different letters for flankers with separate S-R rules). The results indicated that the backward crosstalk effect was mainly driven by a stimulus-based compatibility, as indicated by a significant S2−R1 compatibility effect in the matched and reversed conditions, with little change in this effect between the matched and reversed conditions. Experiment 2 replicated and extended these findings to a psychological refractory period paradigm. The present findings suggest that in the matched and reversed conditions, there was only one S-R rule active at a time.
Audio-visual integration in noise: Influence of auditory and visual stimulus degradation on eye movements and perception of the McGurk effect
Authors: Stacey Jemaine E. , Howard Christina J. , Mitra Suvobrata , Stacey Paula C.
Published: June 2020

Seeing a talker’s face can aid audiovisual (AV) integration when speech is presented in noise. However, few studies have simultaneously manipulated auditory and visual degradation. We aimed to establish how degrading the auditory and visual signal affected AV integration. Where people look on the face in this context is also of interest; Buchan, Paré and Munhall (Brain Research, 1242, 162–171, 2008) found fixations on the mouth increased in the presence of auditory noise whilst Wilson, Alsius, Paré and Munhall (Journal of Speech, Language, and Hearing Research, 59(4), 601–615, 2016) found mouth fixations decreased with decreasing visual resolution. In Condition 1, participants listened to clear speech, and in Condition 2, participants listened to vocoded speech designed to simulate the information provided by a cochlear implant. Speech was presented in three levels of auditory noise and three levels of visual blurring. Adding noise to the auditory signal increased McGurk responses, while blurring the visual signal decreased McGurk responses. Participants fixated the mouth more on trials when the McGurk effect was perceived. Adding auditory noise led to people fixating the mouth more, while visual degradation led to people fixating the mouth less. Combined, the results suggest that modality preference and where people look during AV integration of incongruent syllables varies according to the quality of information available.
Echec imminent : à la recherche d'un profil
Authors: AHUES Mario , Largillier Alain , Meskens Nadine , Vandamme Jean-Philippe
Published: June 2020

Devant le constat, tant en Belgique qu'en France, des faibles taux de réussite en premiêre année universi­taire, nous avons cherché à  dégager le profil des étudiants qui risquent de se trouver en situation d'échec en fin d'année. Ainsi ils pourront bénéficier d'actions ciblées menées par l'université en vue d'augmenter leur probabilité de réussite et ce avant les premiêres évaluations.
Un questionnaire a été élaboré et distribué en début d'année, et ce durant deux années, auprês d'étudiants de la Faculté de Sciences et Techniques d'une université française, d'un IUT (Institut Universitaire Technologique) de la même université et de la Faculté des Sciences d'une université belge. Chaque étudiant a pu être décrit au moyen de 375 varia­bles. Nous présentons dans cet article l'analyse des résultats obtenus.
Cylinder plastic compression by the flat dies
Authors: Непершин Ростислав Иванович
Published: June 2020

Приведено численное моделирование пластического сдавливания цилиндра плоскими штампами по нормали к его оси на основе теории плоской деформации жесткопластического тела. Рассматриваются начальная пластическая деформация с выдавливанием материала на свободную поверхность цилиндра, переходящая в пластическое деформирование высокой заготовки и пластического слоя с конечным отношением длины контакта к толщине. Используются линии скольжения и скорости пластического течения по Прандтлю при изменении формы деформируемого сечения цилиндра с учетом контактного трения при сдавливании пластического слоя. Моделирование представляет практический интерес для оценки предельной нагрузки при контактной деформации цилиндра плоскими штампами и деформировании заготовки при ковке плоскими бойками.

Computer simulation of the rigid-plastic cylinder compression by the flat dies is presented using plane strain ideal plastic theory. Initial contact plastic deformation with material lip forming on the free cylinder surface, followed by the high workpiece and the plastic layer with finite contact length to thickness relation plastic deformation are considered. Prandtl’s slip lines and velocity fields are used for the cylinder section form predictions and plastic layer compression with contact friction consideration. Computer simulation can be used for the limit load estimation with cylinder contact plastic flow, compressed by the flat rigid dies, and cylinder workpiece forging by the flat dies.
On the calculation of the optimal value of the loading force in the conditions of a slow creep in the vicinity of a single microdefect
Authors: Аноп Максим Федорович , Мурашкин Евгений Валерьевич
Published: June 2020

В работе рассматривается проблема расчета величин оптимального нагружающего усилия при деформировании материала в условиях медленного крипа. Решение краевой задачи строится в рамках модели больших упругоползучих деформаций. Полученное численное решение используется для поиска оптимального процесса нагружения необходимого для достиженения заданного размера одиночного микродефекта. Поиск оптимального решения проводится на множестве полиномов сетепни 5 методо полного перебора. Полученное решение анализируется графически и сравнивается с ранее полученныи результатами.

In the paper the problem of calculating of the optimal loading pressure during material deformation under creep is considered. The solution of the boundary-value problem is constructed within the frameworks of the model of large elastic-creep deformations. The obtained numerical solution is used to find the optimal loading process necessary to achieve a given size of a single microdefect. The search for the optimal solution is carried out on the set of 5-order polynomials by a brute-force search. The resulting solution is analyzed graphically and compared with previously obtained results.
Intellectual mobility and the model of its formation in engineering students
Authors: МІХНЕНКО Галина , КУЧЕРЯВА Людмила
Published: June 2020

The paper focuses on intellectual mobility of engineering students as an important quality necessary for their successful professional activity, which can be developed in the environment of a technical university through the integration of professional training and teaching a foreign language. The structural and functional model on the formation of intellectual mobility, previously developed and realised by conducting a pedagogical experiment, has been presented in the paper. The main components of the model (methodological, process-and-content, result-and-evaluation) and their constituents have been described. It is stated that such a model can become an effective tool for representing and realising the process of the formation of intellectual mobility as a quality of future engineers. Keywords: intellectual mobility, model, English for Specific Purposes, intellectual activity, pedagogical conditions.
Organization of the inclusive education of children with special needs in Ukraine: modern accentuations
Authors: CЕРГЕЄВА Валентина
Published: June 2020

The article highlights topical and top-priority issues of inclusive education implementation in Ukraine. Pedagogical inclusion is regarded as an educational paradigm based on the principles of equality, accessibility, and the guarantee of high-quality education for all, which is a fundamental imperative of its effective functioning, and one of the most beneficial forms of education for the children with special needs. The study analyzes the definitions of the basic categories of the issue and the legal basis for ensuring the organization of the inclusive educational environment. The emphasis is laid on the organizational aspects of inclusive education implementation in the institutions of pre-school and general secondary education.
The history of B. Sadovskoy’ cooperation in the journals "Vesy" and "Zolotoe runo"
Authors: ЄЛІСЕЄНКО Анна
Published: June 2020

B. Sadovskoy led an active literary activity in the first half of the twentieth century. In 1904 the editor of “Vesy” V. Bryusov invited the young writer to collaborate in the journal. B. Sadovskoy proved to be a talented literary critic and poet. Nevertheless, his reviews and notes were considered as pretentious and sharp in expressions that led to the condemnation and alienation of many contemporaries in relation to the writer. A few years later B. Sadovskoy became a member of “Zolotoe Runo”. Editorial policy of this journal from the first issue became the subject of controversy in literary circles, especially from the Symbolists who published their works on the pages of “Vesy”. The journals “Vesy” and “Zolotoe Runo” played a considerable role in B. Sadovskoy’ formation as a writer, poet and literary critic.
Prospects for the use of an interdisciplinary approach to the study of human rights (psychology and law)
Authors: СОЛОДОВНІКОВА Христина
Published: June 2020

The article analyzes the prospects of using an interdisciplinary approach to clarify and deepen the understanding of the place and role of a person and personality in the legal system of Ukraine.
Комунікативна компетентність як чинник ефективного спілкування студентської молоді: філософський вимір
Authors: АВДИМИРЕЦЬ Наталія
Published: June 2020

У статті досліджено комунікативну компетентність, як підгрунтя ефективного спілкування та соціальної взаємодії студентської молоді. Висвітлена структура комунікативної компетентності, проаналізовані її складові, розглянуті актуальні сфери комунікативної компетентності студентської молоді. Обґрунтовано необхідність дослідження сучасною наукою комунікативної компетенції як складової професійних компетенцій майбутніх фахівців, а також – як чинника всебічного, гармонійного розвитку сучасної молоді та усталення її буття. Підкреслено, що комунікативна компетентність розвивається не тільки засобами освіти, а й засобами усіх сфер культурно-освітнього простору, у якому функціонує молода людина.
Nghiên cứu giá trị thang điểm tiên lượng ACUITY-PCI ở bệnh nhân có hội chứng vành cấp được can thiệp động mạch vành qua da
Authors: Hoàng Trần Phú
Published: June 2020

ACUITY-PCI SCORE IN STRATIFICATION OF PATIENTS WITH ACUTE CORONARY
SYNDROMES UNDERGOING PERTACUNEOUS CORONARY INTERVENTION
Hoang Tran Phu1
, Hoang Anh Tien2
, Ho Anh Binh3
Background: Pertacuneous coronary intervention (PCI) is used to treated patients with acute coronary syndromes (ACS) in many years. However the outcomes after PCI needs to be evaluated and analysed.
Objective: ACUITY-PCI score in stratification of patients with acute coronary syndromes undergoing pertacuneous coronary intervention. To evaluate the relation between ACUITY-PCI sure and death and major cardiovascular risk factor in these patients
Methods: This research was created from data of 51 patients with ACS and used ACUITY-PCI score to stratification. Six variables were used in this score: insulin-treated diabetes, renal insufficiency, baseline cardiac biomarker elevation or ST-segment deviation, bifurcation lesion, small vessel/diffuse coronary
disease and the extent of coronary artery disease.
Results: ACUITY-PCI score with lower tertile 35.3%; intermediate tertile 15.7%; upper tertile 49 %. 30 day clinical outcomes: Death 13.7%; Reinfarction 1.9%. Event rated increased significanty across tertiles of ACUITY-PCI score: 0% in the lower tertile; 12.5% in the intermediate tertile and 28% in the upper tertile.
The ACUITY-PCI score had the good discrimination (C-statistic = 0.865 ). Age > 60 ; smoke; BMI < 18.49 kg/m2 and triple-vessel disease were univariate predictors of mortality after PCI ( p < 0.05).
Conclusion: ACUITY-PCI risk score is a good tool to prognostic for patients with ACS undergoing PCI in prediction of 30-day death or MI. Event rates increased significantly across tertiles of ACUITY-PCI score.
Key words: Pertacuneous coronary intervention (PCI), ACUITY-PCI score
Đánh giá ảnh hưởng của đau mạn tính lên sức khỏe tổng quát ở bệnh nhân điều trị tại khoa YHCT Bệnh viện TW Huế cơ sở 2
Authors: Lại Thị Kim Lan
Published: June 2020

EVALUATING THE EFFECT OF CHRONIC PAIN TO PATIENT’S GENERAL HEALTH AT
TRADITIONAL MEDICINE DEPARTMENT OF HUE CENTRAL HOSPITAL BRANCH 2

Background: Pain is a very common symptom in the community and it is a leading cause of patients have to meet doctors and come to hospitals. Chronic pain results in poor quality of life, many days lost from work and high direct and indirect costs for the health care system.
Objective: To investigate on chronic pain and general health with their ralated factors on patients at Traditional medicine department. To evaluate the effects of chronic pain to general health.
Participants and method: A cross-sectional survey was performed for patients at Traditional medicine department with the pain and general health questionaire from 6/2018 to 6/2019.
Results: Duration of chronic pain is very long. The common location of pain is low back. Majority of patients reported their pain condition is from moderate to severe level. Majority of patients have general health is lower moderate level.
Conclusion: Chronic pain is one of the major health problems of the population. The common location of pain is low-back. The first is not to determine the effect of pain to general health of patient.
Keywords: chronin pain, general health
Revision of Taiwanese species of Atrachya Chevrolat, 1836 (Coleoptera, Chrysomelidae, Galerucinae): descriptions of three new genera, two new species, and designations of three new synonyms
Authors: Lee Chi-Feng
Published: June 2020

The genusAtrachyaChevrolat is redefined based on study of the type speciesA. menetriesii(Faldermann, 1835). All Taiwanese species ofAtrachyaare transferred to three new genera:A. hirashimaiKimoto, 1976 andA. nitidissima(Chûjô, 1935) are transferred toNeochyagen. nov.;A. mediofasciataKimoto, 1976 is transferred toTsouchyagen. nov.;A. unifasciataTakizawa, 1978 is transferred toChinochyagen. nov. Two species are described:N. chengisp. nov.andN. tsouisp. nov.Atrachya bicoloripennis(Chûjô, 1938) andA. saramao(Chûjô, 1962) are regarded as synonyms ofN. nitidissima(Chûjô, 1935)comb. nov., andMonolepta tsouiLee, 2009 is synonymized withT. mediofasciata(Kimoto, 1976)comb. nov.Monolepta sublataGressitt & Kimoto, 1963 is redescribed and transferred toChinochyagen. nov.Taiwanese records ofMonolepta sublataare based on misidentifications and represent specimens ofC. unifasciata. Variablity of adult color patterns is discussed.
Ultrasonographic features of liver, gallbladder, spleen, kidneys, and urinary bladder of rescued long-tailed macaques, Macacafascicularis
Authors: CARDENIO Paul , ACORDA Jezie , LASTICA-TERNURA Emilia
Published: June 2020

This study was conducted to determine the ultrasonographic features of the liver, gallbladder, spleen, kidneys, and urinary bladder of 24 apparently healthy male and female long-tailed macaques (LTM) and the correlations of organ measurements with body weight and crown–rump length. The animals were grouped into 12 males and 12 females. Examination was performed in sedated LTM using an ultrasound machine with 6.0 MHz microconvex scanner. Ultrasound appearance, dimensions, and echotexture of the liver, gallbladder, kidneys, spleen, and urinary bladder were evaluated. The results showed that there were no sex-related differences in echo mean values, thickness, and length of the selected abdominal organs. The liver was hypoechoic to isoechoic with the right renal cortex, while spleen was isoechoic to hyperechoic to left renal cortex. Spleen was hypoechoic to isoechoic to the liver. Gallbladder and urinary bladder had hypoechoic to hyperechoic thin wall with anechoic lumen. There was a statistically significant and moderate positive correlation between the volume of the left kidney and body weight. The right kidney volume was greater than the left kidney and the total renal volume had a statistically significant and moderate positive correlation with body weight. This study established the reference values for ultrasonographic features of selected abdominal organs of rescued LTM.
The prevalence of gastrointestinal nematodes in sheep (Ovisaries) in the central and south-eastern regions of Ukraine
Authors: MELNYCHUK Vitaliy , YEVSTAFIEVA Valentyna , BAKHUR Tetiana , ANTIPOV Anatoliy , FESHCHENKO Diana
Published: June 2020

The article investigates into the species composition of agents causing gastrointestinal tract nematodes in sheep. It determines the forms of nematodes communities. For this purpose, 710 sheep were examined, 79.58% of which were infected. The fauna of nematodes was represented by 15 species of helminths from 12 genera: Bunostomum, Oesophagostomum, Nematodirus, Chabertia, Cooperia, Trichostrongylus, Ostertagia, Haemonchus, Тrichuris, Aonchotheca, Strongyloides, and Skrjabinema. The indicators of infestation intensity in sheep ranged from 1 to 93 specimens per animal, and the abundance index ranged from 0.01 to 16.96 specimens per animal. The most common nematodes are H. contortus (prevalence, 61.97%), O. circumcincta (59.58%), T. colubriformis (57.35%), Т. оvis (55.21%), N. spathiger (49.01%), Oe. venulosum (42.54%), S. ovis (41.13%), Ch. оvina (36.76%), and T. skrjabini (26.34%). Gastrointestinal nematodes in the body of 99.12% of the infected sheep proceeded as parasitic communities. Most frequently, coinvasions were represented by parasitic communities which consisted of five (prevalence, 14.51%), six (19.44%), or seven (15.92%) species. The study revealed 361 varieties of mixed coinvasions. The most frequent comembers were H. contortus, O. circumcincta, T. colubriformis, Т. оvis, N. spathiger, S. ovis, and Ch. оvina. The data obtained provide an opportunity to increase the effectiveness of measures to combat and prevent gastrointestinal tract nematodes in sheep farms.
Evaluation of mulberry (Morusalba) leaves as a concentrate substitute in rabbit diet: effect on growth performance and meat quality
Authors: KHAN Kamran , ULLAH Inam , KHAN Nazir Ahmad , KHAN Sarzamin
Published: June 2020

Mulberry (Morus alba) leaves contain a high amount of digestible carbohydrates, protein and minerals, making it an attractive, natural, low-cost feed ingredient in rabbit rations. The present study evaluated the effect of stepwise replacement of a concentrate diet with wilted M. alba leaves on growth performance and meat quality of rabbits. Sixty indigenous rabbits (age, 36 ± 2 days) were assigned to 5 diets (12 rabbits per diet). The 5 diets consisted of a commercial concentrate diet (control; WML0), and stepwise replacement of the concentrate with 25% (WML25), 50% (WML50), 75% (WML75), and 100% (WML100) wilted M. alba leaves. Final body weight (1238 g/rabbit), and total (904.1 g/rabbit) and daily (18.8 g/day/rabbit) weight gains were higher (P < 0.05) in rabbits fed with WML50. The WML50 also supported the best (P < 0.05) feed to gain ratio (4.50). Moreover, higher (P < 0.05) reference carcass weight (571.7 g) and a higher dressing percentage (55.8%) were recorded for WML50. Composition of the diets did not alter (P > 0.05) meat pH, water release and cooking loss. In conclusion, M. alba successfully replaced 50% of concentrate in rabbit diet and supported a higher growth performance and carcass yield without negative effects on meat quality
Madera en altura, estado del arte
Authors: Orta B. , Martínez-Gayá J. E. , Cervera J. , Aira J. R.
Published: June 2020

El objetivo es mostrar el panorama actual de la edificación en altura con madera. Comienza con una revisión histórica desde las pagodas orientales (hasta 63m de altura) hasta las visiones de futuro (350m). Se muestra el desarrollo tecnológico que ha llevado la madera maciza hasta los productos industrializados actuales y las investigaciones en desarrollo. Se expone su comportamiento ante el fuego y las propiedades como material estructural en comparación con los materiales estructurales más utilizados para la edificación en altura: mecánicamente es tan competitivo como hormigones o aceros de alta resistencia. Ante acciones horizontales hay varias estrategias y se obtienen las esbelteces máximas alcanzables en altura. Su principal ventaja, desde el punto de vista ecológico, es su capacidad de absorber CO2, lo que, junto con el alto nivel de prefabricación, lo convierte en una alternativa sostenible cada vez con mayor aceptación
Éducation à l’environnement ou acculturation ?
Authors: Bidou Jean-Étienne
Published: June 2020

Cet article présente l’analyse de représentations des relations entre environnement et développement en se basant sur les discours de trois grands groupes de personnes : des Peuls ruraux du Fouta Djallon en Guinée, des lycéens et étudiants de deux villes burkinabées (Bobo Dioulasso et Ouagadougou) et des lycéens de Niort en Poitou-Charentes (France). Ces corpus, traités par un logiciel d’analyse textuelle, montrent que les représentations des jeunes citadins burkinabés et celles des jeunes Français sont très voisines et s’opposent à celles des ruraux Guinéens. Si ces représentations traduisent des différences culturelles, il faut conclure qu’elles n’opposent plus, sur le thème traité, les populations du Nord et du Sud, mais qu’au contraire les ruraux Africains forment un ilot culturel face à une culture urbaine mondialisée à laquelle participent les grands thèmes environnementaux actuels. L’auteur s’interroge dans quelles conditions l’éducation à l’environnement peut œuvrer de façon à être mieux en prise avec les cultures locales.
Biased Data
Authors: Fernandez Abigail Christina
Published: June 2020

Data is just data if it is not put to proper comprehensive usage. Information is Knowledge and Knowledge gets upgraded to wisdom pertaining to insight in the relevant field of analysis. Data Science has become the key that unravels many pitches of interest in diversified fields of quest. It is of optimal stipulation that the solutions that the Artificial Intelligence Algorithms provide should do justice to the intent for which what it was built. But at times, inadvertently the word bias is declaimed, which has become an implicit or explicit inclusion in the Algorithms and the data collection methodologies incorporated. IT companies manoeuvring this technology need to treat this hushed underplay in prediction and decision making with top-notch priority to epitomise this imminent episode of Machine Learning in Data Analysis.
Application of Design Thinking Methodology to the Various Phases of the Software Development Life Cycle
Authors: Shankar Sahana Prabhu , M. S. Supriya , E. Naresh
Published: June 2020

Design thinking is often thought of as a creative way of problem solving. People are told to believe what they are told and what they read, and with that is the downfall of creativity. Designers need to see the world through the eyes of a 5-year-old. People needs to give themselves permission to be creative. It takes intelligence to answer a question, but it also takes creativity to answer the question. People have to imagine the world as it never existed before. Design thinking can be termed as “consumer-centric”, “end-user centric” or simply “human-centric” thinking. It works from the perspective of the user in general with user satisfaction being the primary goal. The methodology that I adopted is thinking from the user's perspective and working towards user's satisfaction as the goal. Design thinking is a problem-solving technique evolved in different fields like architecture, engineering, and business. The key element to the success of designing a software system lies in user participation. Therefore, it was basically developed to derive a solution by understanding the user's need.
Small-Scale Sports Event Marketing Using New Marketing Concepts and Communication Tools
Authors: Beede Park
Published: June 2020

Small-scale sporting events are often characterized as local activities limited in size, support, and resources. However, they fulfill an integral social role in the vibrant lives of local communities. Sports events also attract visitors as participants and spectators, benefitting the local economy and supporting tourism activities. To deliver successful events, coordinated marketing activities should be developed in a cohesive marketing plan. Every sports organization can implement effective marketing tools to increase the visibility of their event and enhance satisfaction among a variety of key stakeholders. This chapter outlines a manageable plan of marketing activities that will improve the odds of a successful event.