bluuebunny/crossref_metadata_2025 huggingface dataset:
Circulating makorin ring finger protein 3 levels decline in boys before the clinical onset of puberty
Authors: Varimo Tero , Dunkel Leo , Vaaralahti Kirsi , Miettinen Päivi J , Hero Matti , Raivio Taneli
Published: May 2016

Objective

Makorin ring finger protein 3 (MKRN3) gene restrains the hypothalamic–pituitary–gonadal axis. In girls, peripheral levels of MKRN3 decline prior to the onset of puberty. We described longitudinal changes in serum MKRN3 levels in boys before and during puberty and assessed the effect of inhibition of estrogen biosynthesis on MKRN3 levels.

Design

Longitudinal serum samples from a double-blind, randomized controlled study in 30 boys (age range: 9.1–14.2years) with idiopathic short stature who received placebo (Pl;n=14) or aromatase inhibitor letrozole (Lz; 2.5mg/day;n=16) for 2years.

Methods

We analyzed the relationships between serum MKRN3 and clinical and biochemical markers of puberty by using summary measures.

Results

Serum MKRN3 declined by 669±713 pg/mL per year (P<0.001). This change was biphasic, as the levels decreased during Tanner genital stage G1 (–2931±2750 pg/mL per year) and plateaued thereafter (–560±1510 pg/mL per year) (P<0.05). During G1, MKRN3 levels in Lz-treated subjects decreased slower than in Pl-treated boys (–782±3190 vs –2030±821 pg/mL per year,P<0.05). The decrease in serum MKRN3 levels in G1 was associated with increases in LH (r=–0.5,P<0.01), testosterone (r=–0.6,P<0.01), and inhibin B (r=–0.44,P<0.05) (n=26).

Conclusion

Peripheral MKRN3 levels in boys appear to serve as a readout of the diminishing central inhibition that controls the onset of puberty.
‘Incidental’ and ‘non-incidental’ thyroid papillary microcarcinomas are two different entities
Authors: Provenzale Maria Annateresa , Fiore Emilio , Ugolini Clara , Torregrossa Liborio , Morganti Riccardo , Molinaro Eleonora , Miccoli Paolo , Basolo Fulvio , Vitti Paolo
Published: May 2016

Objective

Papillary thyroid microcarcinomas (microPTC) may be ’incidental’ (Inc-microPTC), occasionally found at histology after surgery for benign disease or ‘non-incidental’ (Non-Inc-microPTC), diagnosed on clinical grounds. It is unclear whether these different microPTC reflect the same disease. The aim of the study was to compare Inc-microPTC and Non-Inc-microPTC for clinical and histological features as well as for serum TSH, a known factor involved in PTC development.

Design

We evaluated histology and serum TSH levels of consecutive patients submitted to thyroidectomy for goiter with compressive symptoms or for cytological diagnosis suspicious/indicative of PTC.

Methods

In total, 665 consecutive patients (259 with a single thyroid nodule, SN and 406 with a multinodular gland, MN) were included in the study. According to histology, patients were classified as: benign nodular goiter (Benign, n=291); Inc-microPTC (n=92); Non-Inc-microPTC (n=67) and PTC≥1cm (macroPTC, n=215).

Results

Inc-microPTC were significantly more frequent in MN than in SN (66/406, 16.2% vs 26/259, 10.0%, P=0.02). Patients with Inc-microPTC compared with Non-Inc-microPTC were older (mean age±s.d. 53.3±13.2 years vs 44.9±14.8 years, P=0.0002), had a smaller tumor size (median 4mm vs 9mm, P<0.0001), a higher frequency of multifocality (70/92, 76.1% vs 35/67, 52.2% P=0.001) and lower levels of TSH (median 0.6mIU/L, IR: 0.4–1.0mIU/L vs value 1. mIU/L, IR: 0.6–1.4mIU/L vs P=0.0001).

Conclusion

Incidental and non-incidental papillary thyroid microcarcinomas appear to be two different entities.
Excessive training impairs the insulin signal transduction in mice skeletal muscles
Authors: Pereira Bruno C , da Rocha Alisson L , Pinto Ana P , Pauli José R , de Moura Leandro P , Mekary Rania A , de Freitas Ellen C , da Silva Adelino S R
Published: May 2016

The main aim of this investigation was to verify the effects of overtraining (OT) on the insulin and inflammatory signaling pathways in mice skeletal muscles. Rodents were divided into control (CT), overtrained by downhill running (OTR/down), overtrained by uphill running (OTR/up), and overtrained by running without inclination (OTR) groups. Rotarod, incremental load, exhaustive, and grip force tests were used to evaluate performance. Thirty-six hours after the grip force test, the extensor digitorum longus (EDL) and soleus were extracted for subsequent protein analyses. The three OT protocols led to similar responses of all performance evaluation tests. The phosphorylation of insulin receptor beta (pIRβ; Tyr), protein kinase B (pAkt; Ser473), and the protein levels of plasma membrane glucose transporter-4 (GLUT4) were lower in the EDL and soleus after the OTR/down protocol and in the soleus after the OTR/up and OTR protocols. While the pIRβ was lower after the OTR/up and OTR protocols, the pAkt was higher after the OTR/up in the EDL. The phosphorylation of IκB kinase alpha and beta (pIKKα/β; Ser180/181), stress-activated protein kinases/Jun amino-terminal kinases (pSAPK-JNK; Thr183/Tyr185), factor nuclear kappa B (pNFκB p65; Ser536), and insulin receptor substrate 1 (pIRS1; Ser307) were higher after the OTR/down protocol, but were not altered after the two other OT protocols. In summary, these data suggest that OT may lead to skeletal muscle insulin signaling pathway impairment, regardless of the predominance of eccentric contractions, although the insulin signal pathway impairment induced in OTR/up and OTR appeared to be muscle fiber-type specific.
Collateral blood vessels in acute ischemic stroke: a physiological window to predict future outcomes
Authors: Alves Heitor Castelo Branco Rodrigues , Pacheco Felipe Torres , Rocha Antonio J.
Published: May 2016

ABSTRACT Collateral circulation is a physiologic pathway that protects the brain against ischemic injury and can potentially bypass the effect of a blocked artery, thereby influencing ischemic lesion size and growth. Several recent stroke trials have provided information about the role of collaterals in stroke pathophysiology, and collateral perfusion has been recognized to influence arterial recanalization, reperfusion, hemorrhagic transformation, and neurological outcomes after stroke. Our current aim is to summarize the anatomy and physiology of the collateral circulation and to present and discuss a comprehensible review of the related knowledge, particularly the effects of collateral circulation on the time course of ischemic injury and stroke severity, as well as imaging findings and therapeutic implications.
Variabilidade físico-química da farinha de mandioca do Território da Cidadania do Vale do Juruá, Acre
Authors: Álvares Virgínia de Souza , Miqueloni Daniela Popim , Negreiros Jacson Rondinelli da Silva
Published: May 2016

RESUMO A farinha é um derivado da mandioca de grande importância alimentar, porém com pequena padronização, por causa do processo artesanal de fabricação. O objetivo deste estudo foi analisar a variabilidade da farinha de mandioca artesanal, produzida no Território da Cidadania do Vale do Juruá, Acre, e agrupar os municípios produtores de acordo com suas características físico-químicas, por meio de análises multivariadas, determinando sua influência na qualidade da farinha de mandioca. Foram analisadas 138 amostras de farinhas, coletadas nos municípios de Cruzeiro do Sul, Mâncio Lima, Rodrigues Alves, Porto Walter e Marechal Thaumaturgo, com determinação da umidade, cinzas, proteína total, extrato etéreo, fibra total, carboidratos totais, valor energético, acidez titulável, pH e atividade de água. Os dados foram analisados pela estatística descritiva com comparação de médias pelo teste de Tukey e estatística multivariada, de forma complementar entre si; com análises de agrupamento hierárquica, pela distância euclidiana e método de Ward, e, não hierárquica, k-means, análise de componentes principais, pela matriz de correlação, e análise discriminante, pelo método da exclusão progressiva passo a passo. Os resultados mostraram que as farinhas encontram-se dentro das normas de qualidade exigidas em legislação. As diferentes análises multivariadas foram coerentes, indicando que há um padrão de distribuição das características físico-químicas das farinhas, o que sugere padrões no processo de fabricação, distribuídos conforme a localização dos municípios analisados. As características de maior influência na discriminação das farinhas são acidez, pH, atividade de água e umidade, indicando que o modo de fabricação tem grande influência na qualidade da farinha produzida.
Análise de crescimento em cultivares de alface nas condições do sul do Piauí
Authors: Zuffo Alan Mario , Zuffo Júnior Joacir Mario , Silva Luana Maria Alves da , Silva Roberto Lustosa da , Menezes Karen Oliveira de
Published: May 2016

RESUMO Objetivou-se, com este trabalho, avaliar o crescimento de quatro cultivares de alface, nas condições do sul do Piauí, para recomendar os melhores para a região. O experimento foi realizado em casa de vegetação, em blocos casualizados, com avaliação em parcelas subdivididas no tempo, avaliadas em seis épocas (20, 24, 28, 32, 36, 40 dias após a semeadura - DAS) e com os tratamentos correspondentes a quatro cultivares (Americana Rafaela(r), Grand Rapids TBR(r), Crespa Repolhuda(r) e Repolhuda Todo ano(r)), com cinco repetições. Foram avaliados área foliar, número de folhas, diâmetro de coleto, massa fresca da parte aérea, massa seca da parte aérea, de raízes e total e os índices fisiológicos da análise de crescimento. Os cultivares de alface interferiram significativamente nos parâmetros estudados, sendo que Americana Rafaela(r) e Repolhuda todo ano(r), nas condições a que foram submetidas, apresentaram melhores desempenhos e maiores índices morfofisiológicos, cultivados em vaso. Os cultivares Americana Rafaela(r) e Repolhuda todo ano(r) podem ser produzidos nas condições do sul do Piauí.
Seletividade de herbicidas sobre arroz irrigado em resposta à época de semeadura e redução da luminosidade em fases do desenvolvimento
Authors: Venske Eduardo , Schaedler Carlos Eduardo , Ritter Ronan , Fin Silvana Spaniol , Bahry Carlos André , Avila Luis Antonio de , Zimmer Paulo Dejalma
Published: May 2016

RESUMO Diferentes fatores ambientais podem afetar a seletividade de herbicidas às culturas. O objetivo deste experimento foi avaliar os efeitos da época de semeadura e da redução artificial da luminosidade, em diferentes fases do desenvolvimento das plantas, sobre a seletividade de herbicidas e os componentes de produtividade do arroz irrigado. O experimento foi conduzido a campo, na safra 2012/2013, com o cultivar IRGA 424. Os fatores estudados foram: época de semeadura (18/outubro e 09/novembro); herbicidas (testemunha capinada, bispyribac-sodium e penoxsulam) e fases do desenvolvimento da cultura com luminosidade reduzida de 70% [testemunha, plântula (S0-V4), períodos vegetativo, reprodutivo e todo o ciclo]. Foi utilizado o delineamento inteiramente casualizado, em esquema fatorial, com quatro repetições, sendo que os fatores época de semeadura e redução de luminosidade foram dispostos em faixas, visando a viabilizar o experimento. Avaliaram-se: fitotoxicidade visual, colmos e panículas por área, espiguetas por panícula, esterilidade de espiguetas, peso de 1000 sementes e produtividade. Os dados foram submetidos à análise de variância pelo teste F (p≤0,05) e teste de médias de DMS de Fischer (p≤0,05). A época de semeadura influencia na seletividade de bispyribac-sodium, sendo que, quando realizada a semeadura perto do início do período recomendado, em 18/outubro, reduz-se a produtividade do cultivar estudado. A redução artificial de luz em diferentes fases do desenvolvimento não afeta a seletividade dos herbicidas bispyribac-sodium e penoxsulam sobre o arroz irrigado.
Co-inoculation of Rhizobium tropici and Azospirillum brasilense in common beans grown under two irrigation depths
Authors: Peres²* Amanda Ribeiro , Rodrigues³ Ricardo Antonio Ferreira , Arf Orivaldo , Portugal José Roberto , Corsini Daiene Camila Dias Chaves
Published: May 2016

ABSTRACT The alternative technique of co-inoculation or mixed inoculation with symbiotic and non-symbiotic bacteria has been studied in leguminous plants. However, there are few field studies with common beans and under the influence of the amount of irrigated water. Thus, the objective of this study was to evaluate the efficiency of inoculation and co-inoculation of common beans with Rhizobium tropici and Azospirillum brasilense under two irrigation depths. The experiment was carried out in the winter of 2012 and 2013, in Selvíria, state of Mato Grosso do Sul. The experimental design was composed of randomized blocks in split-plot scheme with two irrigation depths in the plots (recommended for common beans and 75% of the recommended) and five forms of nitrogen (N) supply in the split-plots (control non-inoculated with 40 kg ha- 1 of N in topdressing, 80 kg ha- 1 of N in topdressing, A. brasilense inoculation with 40 kg ha-1 of N in topdressing, R. tropici inoculation with 40 kg ha-1 of N in topdressing, and co-inoculation of A. brasilense and R. tropici with 40 kg ha- 1 of N in topdressing) with four repetitions. Co-inoculation increased nodulation in the second year of cultivation. None of the evaluated treatments increased the grain yield in relation to non-inoculated control with 40 kg ha-1 of nitrogen in topdressing, which presented average yield of 2,200 kg ha-1. The use of 75% of the recommended irrigation depth provides similar grain yield to the recommended irrigation depth in common beans cropped in winter.
Absorption of primary macronutrients and soybean growth at different compactation densities and moisture levels in a silt loam soil
Authors: Valicheski Romano Roberto , Brandelero Suzi Mari , Miquelutti David José , K.Stürmer Sidnei Leandro , Tramonti Antonio Luis , Franzão Marcos Cesar
Published: May 2016

ABSTRACT Soybean cultivation is increasing rapidly in the region of Alto Vale do Itajaí, State of Santa Catarina, where there is a predominance of silt soils. The objective of this work was to evaluate the content of primary macronutrients in shoots and shoot and root vegetative growth of soybean (Glicine max L. Merrill) grown in a silt-loam soil under different compactation densities and moisture levels. A randomized block design in a 4x4 factorial arrangement was used, with four compactation densities: 1.00; 1.20; 1.40 and 1.60 Mg m-3, and four soil moisture levels: 0.130; 0.160; 0.190 and 0.220 kg kg-1 and four replications. Each pot consisted of the overlapping of three 150-mm PVC rings, where soil was maintained in the higher and lower part of the pot with a density of 1.00 Mg m-3 and in the intermediate ring, the compactation densities were increased. Values of soil density higher than 120 Mg m-3 negatively affected N, P and K uptake by soybean plants, as well as the plant mass of the shoots and roots. The higher levels of soil moisture reduced the compaction effect and promoted better absorption of P and K.
O CAMINHO E AS SUAS ETAPAS: AS QUATRO NOBRES VERDADES (CATVARYĀRYASATYAṆI), O NOBRE ÓCTUPLO CAMINHO (ĀRYĀṢṬĀṆGIKAMARGA) E OS ESTÁGIOS DOS BUSCADORES
Authors: Andrade Clodomir B. de
Published: May 2016

RESUMO Este artigo objetiva ser uma breve introdução à práxis soteriológica budista, enfatizando, num primeiro momento, as quatro nobres verdades (catvaryāryasatyaṇi), aquele conjunto de intuições fundamentais formuladas pelo Buda desde o seu primeiro sermão; depois se descreve o nobre óctuplo caminho (āryāṣṭāṇgikamarga), o conjunto de práticas ensinadas pelo Buda para a consecução da experiência do despertar; finalmente, descrevem-se os estágios do caminho tanto no ambiente theravādin quanto na tradição mahāyāna.
Inteligência competitiva no contexto das empresas mineiras de artefatos de estanho
Authors: Oliveira Paulo Henrique de , Sade Wagner
Published: May 2016

RESUMO Investiga como as práticas da inteligência competitiva têm sido conduzidas pelas empresas mineiras de artefatos de estanho. Ao todo foram selecionadas 9 empresas, o que representou 90% da população das empresas de estanho operando na respectiva região. Os dados foram coletados por meio da aplicação de um questionário estruturado e analisados por meio das técnicas da estatística descritiva. Os resultados revelaram que a IC tem sido utilizada de maneira praticamente informal, especialmente nas empresas de menores portes analisadas. Observou-se, também, que os respectivos empresários compreendem que a IC é muito importante para o sucesso competitivos dos seus negócios, especialmente porque ajuda os seus gerentes a compreenderem melhor as necessidades dos seus clientes, na descoberta de novas oportunidades de negócios e no desenvolvimento de novos produtos, além do aumento da eficácia das estratégias competitivas utilizadas contra os seus concorrentes.
A COMISSÃO NACIONAL DA VERDADE E SUAS RESSONÂNCIAS NOS DOCUMENTÁRIOS VERDADE 12.528 E EM BUSCA DA VERDADE
Authors: Daltoé Andréia da Silva
Published: May 2016

A partir da entrega do Relatório Final da Comissão Nacional da Verdade (CNV) à Presidente Dilma Rousseff, em 10 de dezembro de 2014, esta Comissão e as criadas em determinados Estados brasileiros para o mesmo fim foram encerradas. Todavia, todo este trabalho de levantamento de dados e de reconstrução da história da ditadura civil-militar no Brasil continua reclamando sentidos, tanto que, em muitos estados, o trabalho continua, através das próprias comissões ou de coletivos que já atuavam na luta por manter viva a memória deste período. Considerando que o Relatório da CNV promoverá diferentes repercussões que farão trabalhar os sentidos da ditadura, agora a partir de uma outra narrativa, objetiva-se, neste artigo, analisar o funcionamento de suas ressonâncias nos documentários Verdade 12.528 (2013) e Em busca da verdade (2015) que, ao discutirem os trabalhos da CNV, apontam para o modo como diferentes materialidades significantes provocam deslizamentos em torno de um mesmo tema.
FORMAÇÃO CONTINUADA E DESENVOLVIMENTO PROFISSIONAL DE PROFESSORES DE CIÊNCIAS: ANOTAÇÕES DE UM PROJETO
Authors: Selles Sandra Escovedo
Published: May 2016

Resumo: Este artigo discute algumas contribuições de um projeto de educação continuada para o desenvolvimento profissional de professores de Ciências. Partindo de uma discussão presente na literatura onde se cunhou a terminologia "formadores de formadores", analisa-se o papel multiplicador dos seus participantes, coordenando ações educativas regionais voltadas a professores de Ciências. São discutidas diferentes dimensões de desenvolvimento profissional, metodológica e institucionalmente consideradas, com especial ênfase, ao que poderia ser tomado como indicadores de desenvolvimento profissional. Sugere-se que programas de formação continuada que valorizem a participação docente e reconheçam o papel multiplicador do professor são, potencialmente, capazes de contribuir para o seu desenvolvimento profissional. O artigo termina por argumentar que a formação continuada de professores, como meio de alimentar o processo de desenvolvimento profissional, deve assentar-se sob uma base pedagógica, que permita a atualização e ampliação do conhecimento científico-educacional, e uma base político-profissional que inclua estratégias de reformulação d as condições da profissão docente.
O gozo da insatisfação na relação sexual
Authors: Lippi Silvia
Published: May 2016

RESUMO: O gozo feminino é considerado por Lacan como Outro em relação ao do homem. Em todo caso, este gozo é difícil de ser discernido, ainda mais que ele pode, como nos mostra a clínica, ser facilmente simulado por uma mulher. Mas por que uma mulher se coloca na posição de simular um orgasmo? O que está em jogo para ela nessa prática? Tentaremos mostrar que a simulação não é apenas sinônimo de frigidez. Não que ela não o possa ser, mas a simulação é também fonte de prazer para uma mulher e, de forma pardoxal, algo capaz de favorecer o "encontro" com o outro.
Neurobiology of neuropsychiatric symptoms in Alzheimer's disease: A critical review with a focus on neuroimaging
Authors: Tascone Lyssandra dos Santos , Bottino Cássio Machado de Campos
Published: May 2016

ABSTRACT The objective of this critical review of the literature was to reveal the neural circuits involved in the occurrence of neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) patients through the association of these symptoms with neuroimaging findings. The search for articles was performed on PUBMED from January 2000 to May 2013, using the key words: Dementia AND BPSD; Dementia AND Neuropsychiatric Symptoms; and Dementia AND Psychosis, Delusions, Hallucinations, Agitation, Depression, Anxiety, Apathy, Euphoria, Disinhibition, Irritability, Aberrant Motor Behavior, Sleep or Eating Disorders. Forty-six articles were reviewed and important contributions, especially regarding the psychopathological concepts discussed, were also considered even if not included in this time period. The available evidence suggests the three most relevant neurobiological models for neuropsychiatric symptoms in Alzheimer's disease are the frontal-subcortical circuits, the cortico-cortical networks, and the monoaminergic system. We discussed the association of the individual symptoms or syndromes with these models.
The association between caregiver distress and individual neuropsychiatric symptoms of dementia
Authors: Truzzi Annibal , Valente Letice , Engelhardt Eliasz , Laks Jerson
Published: May 2016

ABSTRACT Neuropsychiatric symptoms (NPS) of dementia constitute one of the most related factors to caregiver burden and patients' early institutionalization. Few studies in Brazil have examined which symptoms are associated with higher levels of caregiver distress. Objective: To evaluate the caregiver distress related to individual NPS in familial caregivers of patients with dementia. We also examined which caregiver and patient factors predict caregiver distress associated with NPS. Methods: One hundred and fifty-nine familial caregiver and dementia outpatient dyads were included. The majority of the patients had a diagnosis of Alzheimer's disease (66.7%). Caregivers were assessed with a sociodemographic questionnaire, Beck Anxiety and Depression Inventories, and the Neuropsychiatric Inventory - Distress Scale. Patients were submitted to the Mini-Mental State Examination, Functional Activities Questionnaire, and the Neuropsychiatric Inventory. Spearman's rank correlation was used to assess the relationships between the continuous variables. Multiple linear regression analyses with backward stepping were performed to assess the ability of caregiver and patient characteristics to predict levels of caregiver distress associated with NPS. Results: Apathy (M=1.9; SD=1.8), agitation (M=1.3; SD=1.8), and aberrant motor behavior (AMB) (M=1.2; SD=1.7) were the most distressful NPS. The frequency/severity of NPS was the strongest factor associated with caregiver distress (rho=0.72; p<0.05). Conclusion: The early recognition and management of apathy, agitation and AMB in dementia patients by family members and health professionals may lead to better care and quality of life for both patients and caregivers.
Dissociation of depression from apathy in traumatic brain injury: A case report
Authors: Costa Raquel Quimas Molina da , Porto Fábio Henrique de Gobbi , Marrocos Rogério Paysano
Published: May 2016

ABSTRACT Although not evident clinically, lesions to the prefrontal cortex cause great social and functional impairment to patients. The anterior cingulate cortex is intimately involved with motivational behavior and after injury to this area the onset of an apathetic state can be observed. This paper describes the case of a patient with traumatic brain injury to the prefrontal lobe presenting with a depressive syndrome associated with apathetic symptoms. After appropriate treatment for depression, intense apathy was revealed, an irreversible sequelae of the traumatic brain injury, constituting the main barrier to the patient's return of lifestyle and independence.
Coordinated Control of ENaC and Na+,K+-ATPase in Renal Collecting Duct
Authors: Feraille Eric , Dizin Eva
Published: May 2016

Tubular reabsorption of filtered sodium is tightly controlled to maintain body volume homeostasis. The rate of sodium transport by collecting duct (CD) cells varies widely in response to dietary sodium intake, GFR, circulating hormones, neural signals, and local regulatory factors. Reabsorption of filtered sodium by CD cells occurs via a two-step process. First, luminal sodium crosses the apical plasma membrane along its electrochemical gradient through epithelial sodium channels (ENaC). Intracellular sodium is then actively extruded into the interstitial space by the Na+,K+-ATPase located along the basolateral membrane. Mismatch between sodium entry and exit induces variations in sodium intracellular concentration and cell volume that must be maintained within narrow ranges for control of vital cell functions. Therefore, renal epithelial cells display highly coordinated apical and basolateral sodium transport rates. We review evidence from experiments conducted in vivo and in cultured cells that indicates aldosterone and vasopressin, the two major hormones regulating sodium reabsorption by CD, generate a coordinated stimulation of apical ENaC and basolateral Na+,K+-ATPase. Moreover, we discuss evidence suggesting that variations in sodium entry per se induce a coordinated change in Na+,K+-ATPase activity through the signaling of protein kinases such as protein kinase A and p38 mitogen-activated protein kinase.
Hemorragia masiva por traqueostomía: caso clínico
Authors: Pérez-Gutiérrez Norton , Moreno-Rey Ángela Milena , Arango-Amorocho Ginna Karina
Published: May 2016

¿Cuál es el manejo adecuado ante el sangrado o hemorragia masiva por traqueostomía? Aunque es poco frecuente, es una situación de emergencia en la unidad de cuidado intensivo y requiere del reconocimiento y diagnóstico oportuno por parte del personal de terapia, de enfermería y del intensivista, así como de la acción inmediata del cirujano para resolverlo. El caso se publica a fin de revisar el manejo actual que sugiere la literatura, especialmente en lo concerniente al manejo quirúrgico de la fistula, ya que en varias oportunidades el sangrado centinela es ignorado o subvalorado, con el consiguiente desenlace fatal.
Reseña del artículo “Activities and Programs That Improve Children’s Executive Functions”
Authors: Cortés Saavedra Daniela , Marques Daniela
Published: May 2016

La presente reseña desarrolla una línea argumentativa que describe la relevancia del estudio de las funciones ejecutivas en el contexto de la evaluación e intervención. Se describen los principales tópicos discutidos en el artículo, tales como la conceptualización de función ejecutiva, los principios generales de intervención y la eficacia de algunos programas de entrenamiento. Se concluye enfatizando la necesidad de estudiar diferentes métodos de intervención para elegir el que más se adecúe a la individualidad de cada sujeto. De igual forma, se apuntan críticas al interés de la gran mayoría de investigadores en el estudio de métodos de entrenamiento dirigidos a niños escolarizados, poniendo de parte los que no se encuentran vinculados a un proceso de educación formal.
Legal Ethics, Rules of Conduct and the Moral Compass – Considerations from a Law Student's Perspective
Authors: Van Zyl IV Christoffel Hendrik , Visser Jo-Marí
Published: May 2016

When young law graduates enter the legal profession they will undoubtedly be exposed to difficult situations that will demand of them to make difficult decisions, often having to balance conflicting systems of belief and ideas on what ethical behaviour entails. Legal ethics training in law faculties the world over often neglects teaching aspects of morality to focus on reviews of rules of professional legal conduct. This article argues that if legal education is to adequately prepare law graduates for legal practice, it must offer more than reviews of these codes of conduct. To properly assist law students in avoiding pitfalls which may lead to disciplinary action, they must be taught to appropriately use their moral compasses.

This narrative aims to show that the metaphorical moral compass, with the cardinal virtues as possible main points, may serve as the crucial and underlying guide in the avoidance of the pitfalls which may result in a person being struck from the roll, but more than that, that it may aid in the pursuit of personal dreams or goals. The article contributes to the literature on legal ethics by foregrounding the virtues that pertain to sound conduct in a lawyer, as opposed to the rules and codes, in the hope that this may help legal practitioners to decide on what is right and what is wrong.
A MASTECTOMIA E A RESSIGNIFICAÇÃO DO CORPO NO FEMININO
Authors: Pereira Dayane , Martinelli Braga Ana Aparecida
Published: May 2016

O câncer de mama é o segundo tipo de câncer mais frequente no mundo e o mais comum entre as mulheres. A cirurgia de mastectomia é o mais invasivo dos tratamentos cirúrgicos para esta patologia, e traz sérias implicações para a paciente. Este trabalho visa abordar questões referentes às estratégias de enfrentamento utilizadas no processo de adoecimento, bem como a percepção das pacientes sobre sua autoimagem pré e pós cirúrgica; identificar impactos psicológicos, físicos e sociais causados pela cirurgia e pelo tratamento quimioterápico; avaliar as percepções referentes à temática da morte e às dimensões do medo que este tema desperta. O estudo contou com levantamento bibliográfico e pesquisa de campo, na qual a coleta de dados foi feita através de entrevista semiestruturada, aplicada em dois momentos – antes e depois da cirurgia – em quatro participantes que estavam em tratamento oncológico em clínica particular de Salvador - BA. Com os dados obtidos, foram selecionadas quatro categorias de análise. Como resultado, concluiu-se que o recebimento do diagnóstico de câncer fez com que a paciente refletisse sobre questões como o sentido da sua vida e o medo da morte; para elas a estética não diz respeito apenas ao que é belo, mas se refere à identificação com o feminino; observou-se também que a crença em Deus é algo que possibilita e potencializa o estabelecimento da confiança no tratamento e na possibilidade de cura; e que a atuação da equipe multidisciplinar de assistência pode otimizar o tratamento quando esta trabalha de forma humanizada.
PERFIL DAS PUBLICAÇÕES CIENTÍFICAS BRASILEIRAS SOBRE A PSICOLOGIA SOCIAL PICHONIANA
Authors: Magalhães Cruz Lucas , Teles Jesus Barbosa Verena Dalton
Published: May 2016

Este artigo é resultado de uma pesquisa bibliográfica exploratória que teve como objetivo traçar o perfil da produção científica brasileira referente à psicologia social de Enrique Pichon-Rivière nas bases de dados do Scielo (Scientific Electronic Library Online) e do Pepsic (Periódicos Eletrônicos de Psicologia) com os descritores “pichon” e “grupo operativo”. Foram encontrados 90 artigos, sendo 56 compatíveis com os critérios de inclusão na pesquisa, os quais foram analisados com base nas seguintes classificações: título do trabalho, ano de publicação, periódico de publicação, objeto de estudo e/ou intervenção, tipo de estudo, temáticas dos artigos, formação do(s) autor(es), sexo do(s) autor(es) e número de autor(es). O tipo de formação dos autores também foi analisado com base nos dados contidos na plataforma Lattes sobre eles. Por fim, reflexões e discussões sobre as informações encontradas compõem um panorama das publicações sobre psicologia social pichoniana no Brasil.
AS PRÁTICAS ITINERANTES DE CUIDADO NO CONTEXTO DA SAÚDE MENTAL NO BRASIL
Authors: Santos Emile Costa , Azevedo Fábio Giorgio Santos
Published: May 2016

O processo da Reforma Psiquiátrica no Brasil desencadeou mudanças nas formas de atenção em saúde mental. Foram criadas novas tecnologias de cuidado, buscando uma aproximação com o território de vida dos usuários. Este estudo tem como objetivo problematizar os alcances, as repercussões e as bases teórico-metodológicas das práticas de cuidado itinerantes em saúde mental desenvolvidas no Brasil, após a reforma psiquiátrica. O objetivo geral do estudo foi conhecer as práticas de cuidado itinerantes em saúde mental desenvolvidas no Brasil, após o início do processo de Reforma Psiquiátrica. Os objetivos específicos foram identificar as bases teórico-metodológicas das práticas itinerantes em saúde mental e investigar suas repercussões. Por meio de uma revisão de literatura, foi possível conhecer materiais publicados sobre a temática, identificando relações e limitações de práticas que tomam o território e o movimento como elementos para a construção de um cuidado singular. Foram utilizados livros e as bases de dados bibliográficos Literatura Latino Americana e do Caribe em Ciência da Saúde (LILACS) e Scientific Electronic Library Online (SciELO). Os descritores escolhidos foram “práticas”; “território”; “saúde mental” e “cuidado”. Foram selecionados para o desenvolvimento do trabalho aqueles com correspondência ao tema “Práticas itinerantes em saúde mental”, segundo indicação do resumo ou palavras-chave, que estavam disponíveis em português, com período de publicação igual ou superior a 2009. Concluiu-se que as práticas de cuidado itinerantes teriam potencial de gerar transformações em todos os agentes envolvidos, contemplar grupos populacionais historicamente excluídos e garantir o território de vida como estratégia de promoção da saúde
Current feasibilities of early ovarian cancer detection
Authors: Khadzhimba Anzhella S
Published: May 2016

We analyzed results of laparoscopic surgical treatment of 349 patients with ovarian tumors. Before surgery besides standard examination ultrasonography of pelvis and Ca-125 estimation was performed. After comparing of preoperative diagnosis with histopatological report was identified low sensitivity and specificity of ultrasonography and Ca-125 for assessment of tumor malignancy potential (32,35 %, 31,82 % and 72,55 %, 68,36 % respectively). It was concluded that nowadays the only method of early ovarian cancer detection is surgical treatment of patients with ovarian tumors, who have ultrasonography malignancy markers and increased Ca-125 level.
The phenomenon of fluorescence in immunosensors.
Authors: Kłos-Witkowska Aleksandra
Published: May 2016

The phenomenon of fluorescence in immunosensors is described in this paper. Both structure and characteristics of biosensors and immunosensors are presented. Types of immunosensors and the response of bioreceptor layers to the reaction with analytes as well as measurements of electrochemical, piezoelectric and optical parameters in immunosensors are also presented. In addition, detection techniques used in studies of optical immunosensors based on light-matter interactions (absorbance, reflectance, dispersion, emission) such as: UV/VIS spectroscopy, reflectometric interference spectroscopy (RIfs), surface plasmon resonance (SPR), optical waveguide light-mode spectroscopy (OWLS), fluorescence spectroscopy. The phenomenon of fluorescence in immunosensors and standard configurations of immunoreactions between an antigen and an antibody (direct, competitive, sandwich, displacement) is described. Fluorescence parameters taken into account in analyses and fluorescence detection techniques used in research of immunosensors are presented. Examples of immunosensor applications are given.
Algoritmos para Otimização do Desempenho de Geradores a Relutância Variável Aplicados em Geração Eólica
Authors: Barros Tárcio A. S. , Filho Paulo S. Nascimento , Moreira Adson B. , Ruppert Ernesto
Published: May 2016

O desempenho do gerador a relutância variável (GRV) está diretamente relacionado às variáveis de ajustes do seu acionamento. Neste trabalho são propostos algoritmos para obter, através de simulações dinâmicas, os parâmetros ótimos de acionamento do GRV quando aplicado em geração eólica. Através de funções de otimização os parâmetros de acionamento do GRV para baixas e altas velocidades de operação são obtidos para manter o balanceamento entre as oscilações de torque, perdas magnéticas e perdas elétricas. Os parâmetros ótimos de acionamento foram verificados experimentalmente e foi confirmada a eficiência da metodologia proposta neste trabalho.
Pemodelan Aplikasi Enterprise Resource Planning Untuk Pondok Pesantren (Pemodelan Aplikasi Proses Akademik)
Authors: Yaqin M. Ainul , - Syahiduzzaman
Published: May 2016

Abstract— Pesantren is an institution or organization that is engaged in Islamic religious education-based community education diniyah or integrated with other types of education. As a boarding school organization requires good management information systems by implementing an integrated boarding school. The information system is an Enterprise Resource Planning (ERP) system that covers all business processes in a boarding school and focused on planning and documentation of transactions. ERP is the application used by the manufacturing company in operation. There is therefore a fundamental conceptual differences between the manufacturing process with the process of education at boarding school, so as to generate the appropriate ERP and can be used by the boarding school, the system needs to be modeled. Modelling done by creating a process diagram and diagram data.
The NICU Mom Who Rarely Visits and What You Can Do About It
Authors: Discenza Deborah
Published: May 2016

ABSTRACT

NICU nurses often worry about NICU moms who are not able to visit their babies regularly and rightfully so. The mother is key to not only the baby’s ability to survive but also thrive, and spare visits do little to help with the bonding process. This article provides solid tips on increasing the NICU mom’s visits using strengths and positives instead of guilt.
Patient-Centered Care and Population Health
Authors: Harwood Jared L. , Butler Craig A. , Page Alexandra E.
Published: May 2016

As health care increasingly emphasizes high value, the terms “population health” and “patient-centered care” have become common, but their application is less clear. Patient-centered care encourages using data to optimize care for an individual. Population health offers a framework to consider how to efficiently and effectively manage a condition for a population, how prevention affects large groups, and the specific distribution of a given disorder. Integrating both concepts into practice can facilitate required outcome-measure reporting and potentially improve patient outcomes. Clinical practice guidelines and appropriate use criteria are examples of reconciliation of these topics. By embracing attempts to decrease variation in treating musculoskeletal disorders while personalizing delivery to individual patients, surgeons may benefit from the improvement of both efficiency and patient experience.
The Effectiveness of the Latarjet Procedure in Patients with Chronic Locked Anterior Shoulder Dislocation
Authors: Li Yue , Jiang Chunyan
Published: May 2016

Background:

Chronic locked anterior shoulder dislocation is a difficult clinical problem for patients and surgeons. Prior studies have proposed a variety of surgical techniques to address this problem; however, the failure rate is high. To our knowledge, there have been no previously published studies on the clinical outcome of the Latarjet procedure for the treatment of chronic locked anterior shoulder dislocation. The purpose of this study was to evaluate the short-term subjective, objective, and radiographic outcomes of patients with chronic locked anterior shoulder dislocation after a Latarjet procedure.

Methods:

From January 2005 to January 2013, 43 patients with chronic locked anterior shoulder dislocation were treated surgically in our institution. Open Latarjet procedures were performed in 35 patients. A subscapularis tenotomy or split was chosen on the basis of the ability to achieve open reduction. Outcomes were assessed preoperatively and postoperatively with the American Shoulder and Elbow Surgeons (ASES) score, the visual analog scale (VAS) for pain, the University of California Los Angeles (UCLA) shoulder rating scale, and the Constant-Murley rating scale. A comparison of the clinical outcomes among the patients who underwent subscapularis tenotomy and repair, those who underwent a procedure that used the subscapularis-splitting technique, and those who underwent a concomitant humeral head replacement was performed.

Results:

Twenty-five shoulders of 25 patients were available for a mean follow-up of 31.6 months. At the time of the latest follow-up, the range of motion and the shoulder functional evaluations (VAS [p = 0.02], ASES [p = 0.01], Constant score [p = 0.01], and UCLA score [p = 0.04]) were significantly improved. The overall redislocation or subluxation rate was 48% (12 of 25): 0% (0 of 5) for the subscapularis-splitting group, 53% (8 of 15) for the subscapularis tenotomy and repair group, and 80% (4 of 5) for the humeral head replacement group. The ASES score (p = 0.006), UCLA score (p = 0.014), Constant score (p = 0.046), and external rotation (p = 0.048) were significantly better, and less severe glenohumeral osteoarthritis was found in patients who had undergone a Latarjet procedure with subscapularis-splitting compared with those who had undergone subscapularis tenotomy and repair.

Conclusions:

The Latarjet procedure for the treatment of chronic locked anterior shoulder dislocation can be successful if the shoulder reduction can be performed without requiring a subscapularis tenotomy. If this reduction is not possible, then other surgical reconstruction should be considered.

Level of Evidence:

TherapeuticLevel IV. See Instructions for Authors for a complete description of levels of evidence.
Performance of Hybrid and Single-frequency Impulse GPR Antennas on USGA Sporting Greens
Authors: Freeland Robert S. , Allred Barry J , Martinez Luis R , Gamble Debra L , Jones Brian R , McCoy Edward L
Published: May 2016

The utility of employing ground-penetrating radar (GPR) technologies for environmental surveys can vary, depending upon the physical properties of the site. Environmental conditions can fluctuate, altering soil properties. Operator proficiency and survey methodology will also influence GPR findings. Therefore, GPR equipment performance evaluation involves standardized tests that are frequently conducted indoors within laboratory-controlled environments.

This study uses outdoor United States Golf Association (USGA) putting greens as a structure for GPR testing for surveying practitioners. These USGA putting greens provide a tightly controlled environment because many golf courses and sports turf fields adhere to strict USGA construction and irrigation guidelines. Past studies on several USGA greens show that GPR provided precise and accurate profiles of root-mixture depth, gravel-blanket thickness, and drain-tile layout. Results are independent of locale, as all USGA putting greens are virtually identical.

In this project, the performance of various GPR antenna frequencies on USGA greens was assessed. This research determined that an efficient antenna for routine profiling of turf putting greens is in the 400- to 800-MHz range. Other frequencies also performed well for a particular target or task, such as for profiling sub-grade depths. The study also compared the performance of a hybrid antenna design with the performance of fixed-frequency antennas and found that the hybrid frequencies fit well for profiling turf greens. Greens management staff may have concerns regarding damage to high-value turf from geophysical survey trafficking. Proposed surveying practices and procedures can help lessen these concerns.
Performative Trolling: Szubanski, Gillard, Dawson and the Nature of the Utterance
Authors: Morrissey Belinda Caroline , Yell Susan
Published: May 2016

In 2012 the Australian public witnessed three important examples of trolling play out in the public sphere that are the focus of this paper: the trolling of Julia Gillard’s Facebook page when she attempted to discuss education policy, the anonymous trolling of Charlotte Dawson’s Twitter page, and the trolling of Magda Szubanski on YouTube after she came out on The Project. These attacks may seem similar in that a public persona has been ridiculed and denigrated in flamboyant onslaughts. However, we will argue that there are important differences in the effects of these attacks, and that underpinning these are differences relating to the individual persona, the social medium and the nature of the utterance. The attacks on Gillard and Szubanski are primarily descriptive attacks on a deliberate and somewhat stage-managed public performance of identity, not a call to action. On the other hand, the anonymous trolling of Charlotte Dawson, which led directly to her attempted suicide, is clearly a performative utterance from the start, meant to have consequences on the object of attack. In Dawson’s case, the separation between her public persona and her private self is far less distinct than in the case of Gillard or Szubanski. These instances demonstrate that trolling exists on a performative continuum, engaging in constant disruption, but also lending itself to the production of social action. The kind of impact trolling will have depends, thus, on the affordances of social media, the persona under attack, and on the very nature of the utterance itself.
Persona - An Old Public Relations Problem?
Authors: Mackey Steve
Published: May 2016

This essay uses the neologism citizen public relations to express a view of the phenomena examined by persona studies implying that public relations studies might be regarded as an antecedent discipline to the former. It goes on to suggest potentially intriguing differences and similarities to do with political and epistemological problematics. The central theme is that the term identity is simultaneously the key link and the key contrast between the two disciplines. This is because the term identity is usually deployed at the internal, psychological, subjective level by scholars of persona while it is usually applied to external, material objects and events by the public relations industry and its academia. The essay also makes the point that both areas of study can be unified as different species of the genera rhetoric in the traditional sense of that still older field. This coincidence and dissonance may invoke a debate which can lead to theory development in all three fields. The fields are not comprehensively surveyed – a process which would be lengthy and might bring up many contrasting perspectives. Instead the work of representative leading authors is presented to make a prima facie case.
Quasi-Subject Commodities - Labour, Minimalism, and the Social Life of Things
Authors: Smith Paul
Published: May 2016

Commodities play an integral role in the creation and maintenance of personas - to such a degree that they begin to take on characteristics of labor, provenance, and politics, such as distressed clothing or fair trade labels. This essay proposes that we have begun to freight our commodities with their own personas and imagined subjecthoods, and that this shift is foreshadowed in the transformation of artistic practices in the late twentieth century.
Two theories on the status of contemporary artworks have come to recent prominence - David Joselit’s “Painting Beside Itself,” which argues that artworks need image not just their status as commodities but rather their circulation and [social] networks, and Isabelle Graw’s claim that artworks are being reconsidered as imaginary “quasi-subjects.” Thus, artworks are being equated with persons, not by their looks but by their actions. This new apprehension of objects finds its own roots in American sculptural debates of minimalism in the late 1960’s, where theorists resorted to ascribing subjectivities to objects to account for the relentless anthropomorphism of even those works which attempted to fully excise the human form.
Proponents of “quasi-subjecthood” argue from two tacks: the object either is a subject of its own, or is propped on the “ghostly presence” of its maker. I believe this indicates two predominant characterizations of commodities: full subjects, or signs of an absent maker. Both arguments flirt with a fetishism that, in giving personas and personalities to objects, threatens to erase the social conditions in which each object is made. However, there may be a way in which these imaginaries can be harnessed as prosthetics for our communities. This essay explores possible avenues for artists and critics to create ethical objects for societies of art.