bluuebunny/crossref_metadata_2025 huggingface dataset:
Peningkatan Kreatifitas dan Efektifitas Pembelajaran Daring Matematika Bagi Guru SMP di Kecamatan Pattalassang melalui ISpring dan GeoGebra
Authors: Aris Naimah , Erawaty Nur , Andriani Irma , Massalesse Jusmawati , Kasbawati Kasbawati , Thamrin Sri Astuti , Nofri Okta , Zakir Muhammad , Sahriman Sitti
Published: March 2022

Daring mathematics study leaves pupils with troubles and anxiety after more than a year of daring learning. Furthermore, students often struggle to understand instructional materials that need graphic interpretation when learning mathematics. This activity aims to improve the competence of mathematics teachers with skills using the iSpring and GeoGebra so that they can create creative and effective learning media so that their virtual mathematics learning becomes more interesting and understandable for students. This activity is conducted daring via Zoom and live on YouTube, as well as offline meetings that are carried out with due observance of health protocols. Lectures, demonstrations on the use of iSpring and GeoGebra, as well as monitoring and evaluation are methods used in daring and offline activities. The target audience for this community service is Middle School Mathematics teachers in Pattalassang District. The results of the training showed an increase in the understanding and skills of mathematics teachers in utilizing iSpring and GeoGebra multimedia. This improvement in IT skills can contribute to increasing creativity and effectiveness in learning mathematics in the classroom.
Studi Pengenalan Teknologi Artificial Intelligence Bagi Guru dan Siswa SMK Nurul Islam Larangan
Authors: Sasmito Ginanjar Wiro , Apriliani Dyah , Nishom M.
Published: March 2022

SMK Nurul Islam is a vocational high school located in Larangan sub-district, Brebes district, which was founded by the Nurul Islam Slatri educational foundation. Based on the results of an initial survey conducted at partners, that students, teachers, and employees (+- 80%) have heard of the industrial revolution 4.0, but only 30% have heard of Artificial Intelligence. And from the survey, it was found that only 2% have understood and understood Artificial Intelligence technology, which has been applied in almost all sectors of life. The survey results also show that all teachers, employees, and students are familiar with the use of information technology, such as: laptops, smartphones, and the internet. However, the current trend of information technology development is that many do not understand, especially regarding the application of the concept of Artificial Intelligence technology, such as: Face Recognition, Speech Recognition, Expert System, Chatboot, Image Detection, and others. Therefore, community service activities were carried out with the theme Introduction to Artificial Intelligence Technology. The methods of presentation, dialogue and demonstration are carried out in the implementation of these community service activities. Based on community service activities and the comparison between the results of the pre-test and post-test, it is obtained that the knowledge and understanding of partners, namely: students and teachers of SMK Nurul Islam Prohibition on Artificial Intelligence is increasing.
Perancangan Sistem Pemanenan Air Hujan Skala Rumah Tangga untuk Pemenuhan Kebutuhan Air Bersih dan Konservasi Air Tanah
Authors: Habibi Aldi Ainun , Siswoyo Hari , Haribowo Riyanto
Published: March 2022

The problems that commonly occurred in the field of water resources were the lack of clean water in the dry season and excess water in the wet season. Those problems may impact on efforts to fulfil the need for clean water. One of the efforts that can be used to overcome those problems is rainwater harvesting. The purpose of this research was to design a rainwater harvesting system to fulfil the need for clean water during the dry season and groundwater conservation in the wet season. The design of the system includes the roof of the rainwater harvesting building, rainwater harvesting reservoirs, infiltration wells, and rainwater quality treatment equipment. The roof of the rainwater harvesting building was designed with a size of 6.50 m x 5.00 m. The runoff discharge from the roof is 1,084.02 liters/hour. The available rainwater harvesting reservoir has a capacity of 5,300 liters. There were 2 units of infiltration wells that function to absorb abundant rainwater from rainwater harvesting reservoirs, each well is 0.80 m in diameter and 1.35 m deep. Utilization of water from rainwater harvesting reservoirs can be done after going through the process in rainwater quality treatment equipment. The results of this activity can be recommended for widespread application.
Elevación de los niveles de transaminasas inducidos por tocilizumab durante el tratamiento para infección severa por SARS-CoV-2: Estudio meta-analítico
Authors: Oscanoa Teodoro J. , Julca Dante I. , Lapeyre-Rivera André , Jiménez-Pelayo Andy , Julón-Buitrón Jesús , Limache-Canaza Leonardo , Juárez-Pérez Emilia , Julca- Alvarado Joaquín , Londoñe-Sullca Richard , Liñer-Mendoza Carlos , Lavado-Degracia Pedro , Lázaro-Ríos Luis
Published: March 2022

Objetivo: estudio sistemático de incremento de los niveles de transaminasas hepáticas inducidos por tocilizumab (TCZ) en pacientes con infección por SARS-CoV-2. Material y métodos: Se realizaron búsquedas en PubMed, EMBASE y Google Scholar, de estudios publicados entre enero 2020 y agosto 2021. Se incluyeron estudios que reportaban datos con niveles de transaminasas hepáticas (aspartato-aminotransferasa o AST y alanino- aminotransferasa o ALT) en pacientes infección por SARS-CoV-2 en tratamiento con TCZ, ya sea en estudios de casos y controles o cuando se median dichos niveles antes y después de terapia en un mismo paciente. La calidad de los artículos fue evaluada de acuerdo con la escala Newcastle Ottawa (NOS). Se extrajeron datos sobre el diseño del estudio, país, número de pacientes, edad y sexo. Se aplicó un modelo de efectos aleatorios para la construcción del diagrama de árbol en base a la delta de la media y desviación estándar de los niveles de ALT y GPT de los casos y controles, de cada uno de los reportes incluidos, con un intervalo de confianza (IC) del 95%. Resultados: Se identificaron 5 estudios de casos y controles para su inclusión, que totalizaron un total de 511 pacientes. La media de edad fue 62,3 + 5,0 años y el 78,8 % fueron varones. La puntuación media de NOS de los estudios incluidos fue 7,8 + 0,4. La dosis utilizada de TCZ fue de 8mg/kg/día. En el diagrama de árbol se observó que la delta de la media de variación de la ALT y AST fueron 0,33 (delta 95% intervalo de confianza: 0,17-0,5; I2 =73% p<0,05) y 0,34 (95% IC: 0,17-0,51; I2=84% p<0,05), respectivamente. En un estudio se reportó normalización de ALT y AST a la 3ra semana, y el resto de estudios no reportó datos de evolución. Conclusión: El uso de TCZ en la infección por SARS-CoV-2 está asociado con elevación de ALT y AST, sin embargo, sus niveles no cumplen criterios de injuria hepática inducida por medicamento y aparentemente es autolimitado. Se requieren más estudios para confirmar la naturaleza temporal de la elevación de las transaminasas asociada al TCZ.
Enfermedad de Castleman versus tuberculosis generalizada: un caso de fiebre de origen desconocido
Authors: Niño-Morin Edgard , Sánchez- Morillos Daniel , Barreda-Celis Rafael
Published: March 2022

Se presenta el caso de una mujer de 25 años con fiebre de origen desconocido, cuyo estudio de biopsia de ganglio cervical se reportó como enfermedad de Castleman, pero que al seguimiento resulto siendo tuberculosis multisistémica. Recibió tratamiento antituberculoso con buena evolución clínica y de laboratorio en el seguimiento. Se enfatiza que, ante enfermedades de baja prevalencia, como la enfermedad de Castleman, se debe descartar tuberculosis en países como el nuestro.
Live Art Scotland Practitioner Directory
Authors: Greer Stephen , White Bryony
Published: March 2022

The Practitioner Directory is a free resource listing artist residencies, funding schemes and professional development programmes open to interdisciplinary artists working in Scotland.
Pengaruh Rasio Keuangan Terhadap Return Saham Pada Perusahaan E-Commerce Di Bursa Efek Indonesia
Authors: Meilanty Meilanty , Setiawati Lulu
Published: March 2022

Laporan keuangan mencerminkan suatu gambaran kinerja keuangan bagi             sebuah perusahaan. Rasio - rasio pada laporan keuangan dapat memberikan      gambaran tentang kondisi kesehatan keuangan pada sebuah perusahaan.    Kinerja keuangan akan mempengaruhi kepercayaan untuk menanamkan    investasinya. Biasanya akan melihat perkembangan saham yang terjadi di           Bursa Efek. Faktor keamanan keuangan sebuah perusahaan akan menjadi      pertimbangan untuk memutuskan pilihan investasi. Saat ini kebanyakan             menentukan investasinya pada pembelian saham. Saham masih dianggap paling   aman untuk investasi. Salah satu alasan memilih saham, karena return saham   dianggap memberikan nilai harapan lebih dari investasi lainnya. Pada   perusahaan E-commerce memberikan persepsi bahwa, dengan banyaknya             peredaran saham, maka bertambah pula kepercayaan terhadap perusahaan          tersebut. Ini akan memberikan pengaruh positif perkembangan Bursa Efek      Indonesia, terutama bagi perusahaan E-commerce
Drug of Choice in The Treatment of Protozoa Infection in Indonesia
Authors: Trasia Reqgi First
Published: March 2022

Protozoal infections are still reported to be widespread in several regions around the world, especially in areas with subtropical and tropical climates, where the environment is poor in hygiene. This disease is endemic in several areas in Indonesia, both on the island of Java and outside, especially in rural areas. So far, the treatment of protozoal infections still relies on nitroimidazole antibiotics. However, there are a number of reports of resistance and treatment failure with these antibiotics. In Indonesia, there are still few articles that discuss the treatment of parasitic infections. The purpose of writing this article is to review the therapeutic options that can be used in the management of protozoal infections in Indonesia. From this review, it can be concluded that in addition to the nitroimidazole group, clefamide, amphotericin-B, oxytetracycline, trimetoprim-sulfametoxazole, paramomycin, and nitazoxanide can also be used as alternative treatments.
Uji Efektivitas Sediaan Salep Ekstrak Daun Saga (Abrus precatorius Linn) Untuk Pengobatan Luka Pada Kelinci (Oryctolagus cuniculus)
Authors: Rambe Robiatun , Paramitha Ratih , Ginting Ernawaty , Caniago Mita Yusmira Lestari
Published: March 2022

Daun saga (abrus precatorius Linn) memiliki kandungan flavonoid, tanin, triterpenoid yang mampu memberikan efek antibakteri.Penelitian ini bertujuan untuk membuat salep dari ekstrak daun saga (abrus precatorius Linn) dan uji efektivitas sediaan salep terhadap pengobatan luka pada kulit kelinci. Pembuatan salep ekstrak daun saga yang telah memenuhi syarat dan diujikan pada hewan uji kelinci sebanyak 5 ekor dengan perlakuan, dasar salep berlemak (kontrol negatif), gentamicin salep (kontrol positif), ekstrak daun saga 10%, 20% dan 30%. Semua kelinci disayat sepanjang 1,5cm dan diberikan sediaan salep ekstrak daun saga sebanyak 0,2 mL. Luka diolesi tiga kali sehari dengan salep yang diuji.Pengamatan luka dilakukan setiap hari selama 8 hari.Hasil penelitian menunjukkan formulasi salep ekstrak daun saga memenuhi persyaratan uji salep menurut Farmakope Indonesia edisi III.Luka sayat yang dioleskan salep ekstrak daun saga mengalami penyempitan luka, membentuk keropeng dan menutup luka mulai hari ke 3.
Faculty productivity in Zambian higher education in the face of internationalization: Unpacking research, publication and citation at the University of Zambia
Authors: Masaiti Gift Masaiti , Mwila Kennedy , Kulyambanino Cecilia , Njobvu Tommie
Published: March 2022

This paper is based on a study that aimed at examining and interrogating the extent of faculty productivity in Zambia in terms of research, publication and citation with specific reference to the University of Zambia (UNZA). The paper invokes the Network Theory of Internationalisation of Higher Education founded by Johanson & Mattsson (1988).The research design used in this article is a convergent parallel mixed-methods design. The sample size total was 254, of which 244 were academic staff and 10 were key informants from management. Qualitative data was analysed according to emerging themes, while quantitative data was analysed using descriptive and inferential statistics. The findings of this paper seem to suggest that faculties at UNZA were highly involved in research (applied and basic) at 75%, but with poor incidences of transforming research into publication and innovation. Only 38% of respondents published articles annually (increasing to 62% within two years) in local and international journals. While respondents who had published books in the last two years was as low as 19.5%. UNZA productivity output in terms of citation was relatively poor, below the expected standard of h-index and citation index of a flagship university which has a track record of more than 40 years of operation as a fully-fledged comprehensive university. Results primarily showed that the UNZA had an average h-index of 4.50 and a citation index of 156.87 which are significantly lower than the world averages of 17.50 and 971, respectively. The paper finally argues that, UNZA like most of the flagship and comprehensive universities in Africa, are quickly transforming from a teaching university into a research university based on the influence of the global North whose research agenda is central – at the expense of teaching. In order to improve on research productivity, this paper recommends that UNZA deliberately identify relevant industries, and global and regional partners to genuinely collaborate with as a way of leveraging resources and expertise. There is also a growing desire by universities in the global South to work closely together as way of improving their own productivity capacity in terms of research, publication, citation and redefine the concept of internationalization to fit the global South.
SUBSTANTIATION OF TAKING INTO ACCOUNT THE COMPLEX OF HUMAN PHYSICAL PARAMETERS IN THE DESIGN OF VENTILATION SYSTEMS
Authors: Лобанов Дмитрий Валерьевич , Звенигородский Игорь Иванович , Новосельцев Борис Петрович , Кононова Марина Сергеевна
Published: March 2022

Проведен анализ существующих нормативных документов и справочно-методической литературы, используемой при проведении расчетов, связанных с определением тепловыделений и газовыделений от людей, занятых различными видами труда. Выявлено неполное соответствие удельных тепловыделений характеристикам тяжести выполняемой работы для различных видов деятельности, полу и возрасту людей. Уточнены характеристики, определяющие понятие условного (среднего) человека, для которого нормируются тепловыделения. Определены расчетные значения тепловыделений с разделением по возрастным категориям. Представлены графики энергетических затрат и их удельных значений для мужчин и женщин разного возраста, выполняющих следующие виды работ: умственный труд, работа легкая, средней тяжести, тяжелая. Проведено сравнение полученных величин энергозатрат с данными нормативных документов для различных категорий работ. Показана актуальность и необходимость учета данных по тепло-, влаго-, газовыделениям от людей с учетом их физических параметров и прочих условий при проектировании систем микроклимата.

We carried out the analysis of existing normative documents and methodical literature used in the calculations related to the determination of heat and gas emissions from people engaged in various types of work. We revealed incomplete correspondence of specific heat emission to the characteristics of the intensity of the work performed for different types of activity, sex and age of people. As well we specified characteristics determining the concept of a reference ( average ) person for whom heat losses are normalized. Estimated values of heat dissipation by age categories are determined too. Also we present the graphs of energy expenditures and their specific values for men and women of different ages performing the following types of work: intellectual work, light work, work of average intensity, hard work. We compared the obtained values of energy expenditures with the data of normative documents for different categories of work. In the end we show relevance and necessity of considering data on heat, moisture, gas emissions from people, taking into account their physical parameters and other conditions in the design of microclimate systems.
STUDY OF RELATIONS BETWEEN GEOMORPHOLOGICAL, TECHNOGENIC, LANDSCAPE FACTORS AND TRAFFIC NOISE IN VORONEZH-CITY
Authors: Прожорина Татьяна Ивановна , Куролап Семен Александрович , Суханов Павел Алексеевич
Published: March 2022

Приведены результаты исследования зависимости показателей эквивалентного шума от автотранспорта города Воронежа при изменении геоморфологических и техногенно-ландшафтных характеристик территории. Исследование базируется на проведении натурных измерений и построении моделей уровня шума посредством программного обеспечения. Проведен анализ влияния рельефа на распространение шума для двух участков с понижением уровня абсолютных высот местности. Оценено влияние шумозащитных экранов в формировании уровня акустического загрязнения, создаваемого автотранспортом. Исследовано влияние зеленых насаждений на распространение автотранспортного шума. Составлены экспериментальные зависимости эквивалентного уровня автотранспортного шума от рельефа местности, наличия шумозащитных экранов и полосы зеленых насаждений.

The article describes the study of the dependence of equivalent noise indicators from motor transport in the city of Voronezh when changing geomorphological and technogenic-landscape characteristics of the territory. All research is based on application of natural measurements and construction of noise level models by means of software. The work includes: analysis of topography influence on noise propagation for two sites with decreasing absolute terrain heights; assessment of noise protective screens influence in formation of motor transport acoustic pollution level; research of green plantations influence on traffic noise propagation. As well we revealed experimental dependences of the equivalent traffic noise level on the topography, noise protection screens and green areas.
ORGANIZATIONAL, TECHNICAL AND METHODOLOGICAL PREREQUISITES FOR PROFESSIONAL TRANSFORMATION IN HOUSING AND COMMUNAL SERVICES
Authors: Чернышов Леонид Николаевич
Published: March 2022

Представлены предпосылки трансформации кадрового потенциала предприятий ЖКХ, обусловленные организационно - техническими и технологическими изменениями в отрасли, связанными с насыщением объектов капитального строительства современным высокотехнологичным оборудованием и интеллектуальными системами. Отмечено, что в обозначенных условиях эволюция профессий происходит значительно быстрее. Требования к работнику смещаются из области исполнения функциональных обязанностей на достижение конечного результата. Предложено решение проблемы адаптации существующих квалификаций на рынке труда к требованиям, которые диктует технологическая революция, заключающееся в реализации направлений Национальной системы квалификаций, основные функции которой - это внедрение профессиональных стандартов в сферу труда и образования.

The article presents the prerequisites for the transformation of the personnel potential in housing and communal service enterprises. These changes in the industry are due to organizational, technical and technological shifts associated with extensive appearance of high-tech equipment and intelligent systems at the facilities of capital construction. It is noted that in the indicated conditions the evolution of professions occurs much faster. Today not performing functional duties but achieving final result is the focus of basic requirements to the employee. The author offers a solution to the problem of adapting qualifications that exist at present on the labor market to the requirements of the technological revolution. This solution involves implementation of the National Qualifications System initiatives, the main function of which is to introduce new professional standards into the field of labor and education.
ASSESSMENT OF STABILITY OF LOAD-BEARING STRUCTURES IN NUMERICAL SIMULATIONS
Authors: Кузнецов Дмитрий Николаевич , Понявина Наталия Александровна , Емельянов Дмитрий Игоревич , Сазыкин Виталий Геннадьевич
Published: March 2022

Численные расчеты устойчивости строительных конструкций требуют разработки эффективных критериев оценки результатов. Оценку результатов расчета устойчивости конструкций целесообразно выполнять с учетом геометрической формы потери устойчивости и назначения элемента строительной конструкции. В статье рассматривается возможность применения последовательности коэффициентов надежности по устойчивости конструкций, в которой значения коэффициентов ранжированы в порядке возрастания последствий отказов конструкций в строительной системе здания или сооружения. Рассмотрен пример численного расчета устойчивости тестовой расчетной схемы стального каркаса здания автосервиса. Расчет устойчивости тестовой двухэтажной рамной системы здания выполнен в вычислительном комплексе SCAD Office, приводятся результаты расчета. Выполнен анализ первых трех геометрических форм потери устойчивости тестовой рамной системы. Подтверждается, что применение шкалы дифференцированных значений коэффициентов надежности для оценки устойчивости конструкций позволит достигнуть более высокой теоретической строгости расчетов, материалоемкости и надежности при проектировании зданий и сооружений. Материалы данной статьи могут быть полезны при проектировании и совершенствовании методик расчета строительных конструкций.

Numerical calculations of the stability of building structures require development of effective criteria for evaluating results. It is advisable to evaluate the results of structural stability calculations with regard to the geometric shape of the loss of stability and purpose of the structural element. The article considers the possibility of applying a sequence of structural stability reliability coefficients in which the coefficient values are ranked in order of increasing consequences of structural failures in a building or structure's construction system. We consider an example of numerical stability calculation of a test design scheme for a steel frame of a car service building. We carried out the calculation of the stability of a test two-storey frame building system with the SCAD Office calculation package, and give the calculation results. As well we perform analysis of the first three geometric forms of stability loss of the test frame system. It is confirmed that the application of the scale of differentiated values of reliability coefficients to assess the stability of structures will allow us to achieve a higher theoretical accuracy of calculations, material capacity and reliability in the design of buildings and structures. The materials of this article can be useful in designing and improving calculation methods for building structures.
Analysis and quality of biomedical images
Authors:   Djamalov D.R.
Published: March 2022

The analysis of biomedical images is carried out. Analytical expressions to determine the quantum efficiency of the visual analyzer are obtained. The relationship between the capabilities of the visual analyzer and the quality of the original image is determined. The calculation of the eye sensitivity to television noise and its numerical analysis are carried out. It is established that the gain coefficient of iridological television systems should be sufficient to eliminate losses in the visual analyzer associated with its low quantum efficiency.

Keywords
iridological, scan, television camera, progressive scan, interlaced scan, circular scan, radial scan, triangular scan, tracking scan
Validity of the epidemiology of atopic dermatitis is questionable
Authors: Macharadze D.Sh. Macharadze D.Sh.
Published: March 2022

Today, the prevalence rates of atopic dermatitis are very different worldwide. Epidemiological data are primarily influenced by factors such as the lack of a unified approach to the definition of the disease, study design, disease codes, diagnosis, research methods, etc. In addition, it is important what is the severity of atopic dermatitis and the accuracy of the diagnosis. The use of records in electronic records and prescribed prescriptions also indicate insufficiently accurate identification of such patients. It is necessary to clarify the clinical signs of atopic dermatitis, and the codes of diseases, including those misdiagnosed as atopic dermatitis, which directly affects the epidemiology of this disease.
Penggunaan Aplikasi Mendeley Sebagai Kutipan Referensi Penelitian Pada Mahasiswa Akhir STEBIS IGM
Authors: Salim Amir
Published: March 2022

Abstrak

Kegiatan pengabdian kepada masyarakat ini merupakan pemberian pelatihan tentang cara menggunakan aplikasi Mendeley bagi mahasiswa di Sekolah Tinggi Ekonomi dan Bisnis Syariah (STEBIS) Indo Global Mandiri yang akan menyelesaikan tugas akhir atau skripsi. Pelatihan ini dilakukan selama 3(tiga) hari dan pelatihan tentang cara menggunakan software refrensi Mendeley untuk windows dilakukan tanggal 25 Februari 2021. Pelatihan ini dilakukan secara online. Mahasiswa yang mengikuti adalah mahasiswa semester 7 dan semester 8. Pelatihan ini diharapkan dapat memberikan pencerahan kepada mahasiswa agar dapat melakasanakan tugas akhir atau skripsi dengan baik terutama membantu mereka untuk menggunakan aplikasi Mendeley sebagai kutipan refrensi.
The Effects of Okra (Abelmoschus esculentus L.) Immersion Water on Changes in High-Density Lipoprotein and Low-Density Lipoprotein Levels in High Fat Diet Wistar Rat Model
Authors: Setyawati Ika
Published: March 2022

Background. The mortality rate due to cardiovascular disease increases; one of the effects of hypercholesterolemia conditions, dyslipidemia, hypertriglyceridemia, and metabolic syndrome, not handled properly and thoroughly. This phenomenon becomes the factor that the researchers took this research topic. This study aims to determine okra (Abelmoschus esculentus L.) immersion water on an increase in high density lipoprotein (HDL) levels and decrease in LDL (low density lipoprotein) levels in high fat diet model Wistar rats.

Methods. This experimental study used 30 Wistar male rats (Rattus norvegicus) divided into six groups, namely normal rats (P1), positive control (P2), standard (P3), dose 1 treatment groups (P4), dose 2 treatment groups (P5), and dose 2 treatment groups (P6). The data were collected by measuring HDL and LDL levels before and after receiving okra (Abelmoschus esculentus L.) immersion water. The data were analyzed by paired sample t-test, Wilcoxon test, ANOVA test and Kruskal-Wallis test.

Results. This research showed a significant difference in the average level of HDL and LDL in all treatment groups (P4, P5, and P6) after induction of Abelmoschus esculentus L. in a high-fat diet rat model (p <0.05).

Conclusion. It can be concluded that the administration of okra (Abelmoschus esculentus L.) immersion water could be used to increase HDL levels and decrease LDL levels in high fat diet model Wistar rats (p <0.05).
Diagnosis and Management of Wilms Tumor
Authors: Nicodemus
Published: March 2022

Wilms Tumor is one of the malignancies frequently found in children under five years old. This tumor is frequently found coincidentally by parents or caregivers who notice a lump in the children’s abdomen. The specific factors of Wilms tumor have not been detected yet. However, it is often associated with specific syndromes as a predisposing factor and a mutation of specific genes. The symptoms caused by this tumor are varied, starting from asymptomatic without any symptom to severe symptoms due to the tumor distribution to the lung. In general, Wilms tumor attacks one of the kidneys (unilateral) with different grades and particular histology. Generally, the management encompasses surgery, chemotherapy, and radiotherapy, depending on the tumor grade. The patients’ recovery rate and managed survival rate were quite high with a low recurrence rate. Therefore, a clinical approach and skepticism of Wilms tumor become one of the diagnoses in children with an abdominal mass.
Integration of PMSG-Based Wind Turbine into Electric Power Distribution System Load Flow Analysis
Authors: Gianto Rudy , Rajagukguk Managam
Published: March 2022

In this paper, a simple method for modeling and integrating PMSG (Permanent Magnet Synchronous Generator)-based WPP (Wind Power Plant) for load flow analysis of electric power distribution systems is proposed. The proposed model is derived based on: (i) the PMSG torque current equations, (ii) the relationships between PMSG voltages/currents in q-axis and d-axis, and (iii) the equations of WPP powers (namely: turbine mechanical power input, WPP power loss and power output). Application of the proposed model in representative electric power distribution system is also investigated and presented in this paper. The results of the investigation confirm the proposed model validity. The confirmation can also be verified by observing the load flow analysis results where, for each value of turbine power, the substation power output plus the WPP power output is always equal to the total system load plus total line loss (the line loss has been calculated based on the impedances and currents of the distribution lines).
Blockchain Technology in Innovation Ecosystems for Sustainable Purchases through the Perception of Public Managers
Authors: Da Silveira Victor Andrade , Da Costa Stella Regina Reis , Resende David
Published: March 2022

The success of organizational processes is increasingly related to sustainable innovation. The concern with sustainable public purchases has been gaining strength over the years. However, several barriers are found to implementing this practice. At the same time, blockchain advances as technology part of the innovation of industry 4.0 and as a proposal to solve these difficulties. The study aimed to identify the perception of public procurement managers on the use of information systems with characteristic features of this technology, to reduce these barriers and elaborate a proposal for the use of blockchain in open innovation systems. The research developed is qualitative, quantitative and applied, being carried out through the application of a structured questionnaire to purchasing managers using the 92 prefectures of the State of Rio de Janeiro, located in Brazil, with subsequent analysis through descriptive statistics. The results of this work present relevant findings for public procurement through innovation and blockchain technology with the possibility of tracking the entire supply chain, allowing the verification of possible environmental and social damages such as the use of child or slave labor, the use of deforestation wood, counterfeit products, unethical agents, in addition to providing more transparency to the process of acquisition.
Methodical Approaches to the Evaluation of the Competition Level of the Milk and Milk Products of Ukraine
Authors: Popko Olena
Published: March 2022

Competition in the market of dairy products is an important requirement for its existence and development, forcing market operators to introduce more efficient production methods, to offer new concepts and cost proposals, to start working in new segments. Since the main milk producers in Ukraine are agricultural enterprises is extremely important is the proper formation of the market of dairy products in Ukraine, one of the main conditions of formation of which is the high level of competition between manufacturers. The existence of effective competition that balances the interests of subjects of market relations, stimulate innovation and competition in all spheres of activities, is one of the main conditions of development of economy of Ukraine. This competition opens up new opportunities for production improvement and develops the optimal structure of market supply and demand contributes to the optimization of production costs.
The aim of this article is to assess the level of monopolization and competition in the market of milk and dairy products of Ukraine based on the index of market concentration, the Herfindahl-Hirschman index, a measure of dispersion, index of entropy, the Lorenz curve. The distribution of market shares among producers of dairy products was carried out based on exponential distribution law, on the basis of which the simulated distribution of smaller producers, which provide dairy products 45% percent of the market of Ukraine. Assessment of the level of monopolization and competition of the dairy market of Ukraine has allowed systematizing a set of operators of the dairy market and gave an opportunity to find out the percentage of coverage of the domestic market of processing of milk and production of dairy products. During the research, it was found that the market of dairy production in Ukraine is highly competitive that is a positive factor for further development of this market.
The Development of State Regulation of Economic Relations in Field of Bankruptcy in Ukraine
Authors: Hutsaliuk Olexii
Published: March 2022

The article deals with the main stages of becoming a bankruptcy institute in Ukraine as a mechanism for regulating a market economy, examines the development of state regulation of economic relations in the field of bankruptcy in Ukraine, and presents problems and proposals for their solution. The bankruptcy procedure is distinguished and the national aspects of bankruptcy are emphasized. The problems of applying bankruptcy law have been identified. Gaps in national legislation have been identified. The approaches that were identified to identify the goals of the bankruptcy procedure are analyzed and the causes of bankruptcy of domestic enterprises are presented.
Ukraine, as a country aimed at building a market economy, must have an effective bankruptcy institution. The goals of such an institute are to restore the debtor’s solvency and to preserve the business entity. For this purpose it is necessary to improve the normative-legal mechanism of the institute, which would take into account the state of the modern economy, the level of social development, the historical way of life of the people and set the goal of achieving not private interest, but the general goal – restoring the solvency of the debtor.
Bankruptcy means liquidation, sale of property assets of the debtor in order to satisfy the claims of creditors. Liquidation is an extreme measure applied to the debtor if the debtor’s financial recovery measures did not bring a positive result. That is, bankruptcy law has two goals: restoring the solvency of the debtor, and in the event that such a restoration is impossible, satisfying the creditors’ claims in the most equitable way.
Problems of Improvement of the Banking Credit Mechanism as a Means of Stimulating the Development of the Credit Service Market in Ukraine
Authors: Zhavoronok Artur
Published: March 2022

The article investigates the basis of the problem of bank lending. It is determined that with the increase in the volume of loans extended, the number of non-repayable loans to borrowers increases, which in turn leads to a shortage of cash resources and as a consequence affects the level of interest rates on loans. It is stated that one of the reasons for the increase in credit rates is the attraction of expensive resources. It is proposed to control these risks to commercial banks of Ukraine, which will ensure the quality of the loan portfolio. Also, a significant problem in the field of bank lending is the lack of legislative support for its implementation.

Keywords
credit, credit relations, credit policy, credit services market, bank lending.
World Trends in the Development of the Nuclear Energy Complex and their Impact on the Nuclear Industry of Ukraine
Authors: Liashenko Viacheslav , Osadcha Nataliia , Shevchenko Volodymyr
Published: March 2022

The article analyzes development trends of the nuclear-industrial complex. Among the main problems of development of nuclear-industrial complex determined inadequate legal framework, lack of investment. the required amount of enriched uranium in nuclear fuel purchased by Ukraine only in the Russian Federation.
The necessity of development sequence the stages of the innovation-oriented development of nuclear-industrial complex of Ukraine on the basis of strategic determinants. Directly the nuclear-industrial complex, which is the leading element of the nuclear energy complex of Ukraine can be considered a complex sector of the national economy that includes production of uranium, which forms the basis to meet the needs of nuclear power plants in natural uranium in the medium and long term; Zirconia production, which includes the establishment of the production of zirconium, which is the main structural material for the fabrication of nuclear fuel, given its unique physical properties of the weak interaction with neutron flux in the reactorcore; manufacture of ion-exchange materials and to ensure the full production of uranium of Ukraine; production of fuel assemblies and components as a key link in the creation of our own nuclear-fuel cycle; research, design and information support of scientific research. In Ukraine there is no specialized institution that would deal with the coordination of the research questions regarding the development of nuclear-industrial complex.
The significance and weight of the atomic-industrial complex of Ukraine in the creation of the gross domestic product is not significant, but its role is important in ensuring economic security and achieving energy independence of the country. The state of the atomic-industrial complex in other countries of the world has been investigated.
For the development of nuclear-industrial complex, it is advisable to use an innovative approach. This approach is represented as a set of three interconnected units, namely: methodical-information unit; diagnostic-estimated; estimating procedure.
The necessity of increasing the volume of uranium mining, the level of its enrichment and at the same time solving environmental issues of waste disposal has been substantiated.
Intelligent Industries of Ukraine: Major Players and Trends in the Pharmaceutical Industry
Authors: Bryukhovetskaya Natalia , Ivanenko Liliia
Published: March 2022

The results of a study of the current state and development trends of domestic enterprises-manufacturers of pharmaceutical products and drugs, the relevance of which is due to the need for scientific and methodological support of digital transformation of business models of enterprises in the real sector of the Ukrainian economy, are presented. In the context of aggravated competition, the need to create conditions for the development of the domestic pharmaceutical industry is characterized by specific innovative processes, a complex structure, a large number of high-tech jobs, high investment attractiveness, is an essential condition for improving the quality and competitiveness of pharmaceutical products in the domestic market, intellectualization of enterprises. The purpose of the article is to establish trends in the development of pharmaceutical enterprises to further determine the methods of functioning and development of intellectualized industries in Ukraine.
It has been determined that during crisis periods, the dynamics of industrial production of enterprises with a high level of intellectualization is characterized by relative stability against the background of a general decline in business activity. The influence of changes in the direction of global trends in the development of the world pharmaceutical market on the domestic pharmaceutical industry has been established: a double-digit growth trend in sales of prescription drugs (double-digit growth) persists due to the implementation of the reimbursement mechanism, as well as an increase in hospital purchases. Maintaining the market growth trend and the corresponding prolongation of state programs such as “Affordable Medicines” contributes to an increase in demand in the domestic market, which can become a stimulating factor for the further development of domestic pharmaceutical manufacturers – the growth of their business, innovation and investment activity.
The analysis indicates a high level of resilience of the pharmaceutical industry and the enterprises that form it to crisis influences, optimistic expectations regarding further moderate growth in the industry, potential growth in the investment attractiveness of domestic enterprises and their high adaptability to transformations of the business model towards its further digitalization and intellectualization.
Regional Features of Ecotourism Activity Development in Ukraine: Comparative Analysis
Authors: Bezuhla Liudmyla
Published: March 2022

At present, ecological tourism as a priority area of the regional economy needs transformational transformations that will help increase the tourist competitiveness of the regions of Ukraine and sustainable development of territories.
The purpose of this study is a comparative analysis of strategic documents in the development of ecotourism and infrastructure, taking into account regional characteristics. To achieve this goal, methods of analysis and synthesis, comparison, generalization, structural and logical analysis were used.
The article analyses the strategies of regional development for 2021-2027. Based on the analysis, it is established that in a significant number of strategic documents the priority areas include accelerating the achievement of competitiveness and innovation of the region’s economy on the basis of smart specialization. Regional strategies do not address the creation of appropriate conditions for the formation of the institutional environment for the development of ecotourism. Only in the Development Strategies of Lviv and Odesa oblasts, among the strategic goals, tourist attractiveness is recognized due to the formation of the appropriate infrastructure.
At the same time, the term “rural green tourism” is most often used in tourism and recreation development programs implemented in most regions of Ukraine. It is proved that there are differences and inaccuracies in the applied terminology on the problems of ecotourism. The programs usually talk about the formation of tourist infrastructure, but do not say anything about the creation of ecotourism infrastructure. The mechanisms of organizational, economic, informational, financial support for the development of ecotourism activities are not prescribed.
Therefore, it is expedient to make changes and additions to the Strategies of regional development until 2027 and programs for the development of tourism and recreation, the content of which is to include a set of measures to intensify the development of ecotourism and the formation of ecotourism infrastructure.
This will create a positive tourist image of the regions of Ukraine; increase their competitiveness and investment attractiveness; to ensure the growth of employment and the share of tax revenues from business activities in the ecotourism sector; increase the number of domestic tourists, including “weekend” tourists, sales of regional tourist products, the number of tourist routes, the number of newly created ecotourism and recreational facilities, the number of employees in the tourism industry.
Regularities of the Process of Organizational Changes in the Management Structure of the Enterprise
Authors: Shmatko Nataliia
Published: March 2022

The article defines the content of the concept of “stability of the economic and production system”; obtained a meaningful identification of the concepts “sustainability of economic and production system” and “sustainability of organizational development of economic and production system”, the difference between which is taken into account the dynamics. The regularities of the enterprise development processes are determined, namely the consideration of the nature and regularities of organizational transformations of the enterprise management structure in the context of ensuring its sustainable development takes place within two conceptual approaches – subjective and objective, the differences between which are related to their inherent differences. in determining the goals, driving forces and mechanisms of such transformations; regularities of the processes of organizational development of the economic and production system of the enterprise are developed.
The dynamics of internal organizational changes in the context of enterprise development will be determined by the potential impact of such changes on its adaptive properties, which, in turn, will further find appropriate expression in the formation of adequate potential responses to external stimuli.
This approach largely corresponds to the position for which the company is considered in terms of socio-economic system of a higher level of organization. In addition, such an approach can also be considered acceptable and productive in predicting the dynamics of enterprise development by the participant of interaction with him. The application of a subjective approach, based on the consi-
deration of organizational transformations as a manifestation of adaptive and (or) purposeful variability of the enterprise, also finds, in particular, fruitful application in the concept of business process reengineering.
WAYS TO ENSURE THE ACTIVE PARTICIPATION OF PARENTS IN THE EDUCATIONAL PROCESS IN PRESCHOOL EDUCATION
Authors:   Master's student Tashkent State Pedagogical University named after Nizami Tashkent, Uzbekistan, Kamalova Gavkhar A.
Published: March 2022

In the educational process organized in preschool educational institutions, the cooperation of teachers and parents is very important. In the educational process, educators, assistants, parents are involved in creative activities based on the active knowledge of the preschooler, the development of his interests, imagination, physical, mental and artistic abilities, communication skills, and most importantly, the harmonious development of the personality. Cooperation will take place.
TO THE VITAL ISSUES OF REFORMING EDUCATION IN UZBEKISTAN
Authors:   Senior Lecturer Tashkent University of Information Technologies Tashkent, Uzbekistan, Salakhova Elza
Published: March 2022

A lot of efforts and measures are being taken by the state to reform the education sector as a whole. At the same time, there are still problems in the educational sphere of Uzbekistan that need to be addressed.
Quaternary pyroclastics from Santorini/Greece and their significance for the Mediterranean palaeoclimate
Authors:   Laboratoriet for Palaeontologi og Stratigrafi, Geologisk Institut, Aarhus Universi­tet, Friedrich Walter, L. , Pichler Hans ,   Mineralogisch-Petrographisches lnstitut der Universität, Kussmaul Siegfried ,   Escue/a de Geo/ogfa, Ciudad Universitaria "Rodrigo Facio"
Published: March 2022

Radiocarbon data from four different horizons of the Santorini volcanic pile show that an unusually long period of volcanic inactivity of about 15,000 yr preceded the late-Minoan outburst. Three different piant-bearing palaeosols of about 37,000 yr, 18,000 yr and 13,000 yr B.P. can be correlated with interstadials in eastern Macedonia, deep-sea cores from the Mediterranean and interstadials from the northern hemisphere. Fossil plants from the Fira palaeosol, Santorini (- 37,000 yr B.P.) indicate that the climatic conditions at that time were nearly the same as at present. A similar flora with a correspon­ding age of about 37,000 yr B.P. also existed on Lipari/Eolian islands, suggesting that this warm period in the Weichselian was widely developed in the Mediterranean area.