bluuebunny/crossref_metadata_2025 huggingface dataset:
Psychiatric Disorders and General Functioning in Low Birth Weight Adults: A Longitudinal Study
Authors: Lærum Astrid M. W. , Reitan Solveig Klæbo , Evensen Kari Anne I. , Lydersen Stian , Brubakk Ann-Mari , Skranes Jon , Indredavik Marit S.
Published: January 2017

OBJECTIVE:

To examine psychiatric morbidity and overall functioning in adults born with low birth weight compared with normal birth weight controls at age 26 years and to study longitudinal trajectories of psychiatric morbidity from early adolescence to adulthood.

METHODS:

Prospective cohort study wherein 44 preterm very low birth weight (≤1500 g), 64 term small for gestational age (SGA; <10th percentile), and 81 control adults were examined using the MINI-International Neuropsychiatric Interview: M.I.N.I. Plus, Norwegian version, the Global Assessment of Functioning, and questions on daily occupation and level of education. Prevalence of psychiatric disorders from previous follow-ups at age 14 and 19 years were included for longitudinal analysis.

RESULTS:

From adolescence to adulthood, the term SGA group had a marked increase in the estimated probability of psychiatric disorders from 9% (95% confidence interval, 4–19) to 39% (95% confidence interval, 28–51). At 26 years, psychiatric diagnoses were significantly more prevalent in the preterm very low birth weight group (n = 16, 36%; P = .003) and the term SGA group (n = 24, 38%; P = .019) compared with the control group (n = 11, 14%). Both low birth weight groups had lower educational level and functioning scores than controls and a higher frequency of unemployment and disability benefit.

CONCLUSIONS:

Low birth weight was a substantial risk factor for adult psychiatric morbidity and lowered overall functioning. The results underscore the need for long-term follow-up of low birth weight survivors through adolescence and adulthood, focusing on mental health. The longitudinal increase in psychiatric morbidity in the term SGA group calls for additional investigation.
Utilização do serviço de urgência pediátrica: a experiência de um centro português
Authors: Rafael Margarida S. , Portela Sofia , Sousa Paulo , Fernandes Adalberto Campos
Published: January 2017

DOI: 10.15448/1980-6108.2017.1.24919Aims: The excess demand for pediatric emergency services has caused much concern among health professionals and hospital administrators. The aim of this study was to assess the utilization of a pediatric emergency department and to determine whether its use was injudicious. Methods: Retrospective cross-sectional analysis of all emergency cases treated throughout 2012 in a general hospital located in the metropolitan area of Lisbon, Portugal. The data were obtained from the hospital’s computer information system. Each patient was submitted at admission to the Manchester triage system adapted for Portugal, and the episodes were categorized into immediate, very urgent, urgent, standard, non-urgent, and not classified. All those episodes classified as standard and non-urgent were denoted as unjustified urgent episodes. The data were collected anonymously and analyzed by the IBM SPSS Statistics software using the chi-square test and one-way ANOVA at a 5% significance level (p<0.05).Results: We analyzed 37,099 pediatric emergency department episodes, of which 19,478 patients were male (53%), the median age was 4 years (interquartile range of 1-9 years), and 78.4% were up to 10 years old. Of all the episodes, 21,177 (57.1%) were classified as standard and 15,470 (41.6%) as urgent or very urgent. Of these patients, 27,294 (73.6%) used the emergency department during the week and 28,679 (77.3%) between 10 a.m. and 12 a.m. It was found that in 90.8% of very urgent, 97.1% of urgent, and 99.4% of standard episodes, patients were discharged without the need for hospitalization. Conclusions: More than half of the children who used the pediatric emergency department had standard or non-urgent needs, and almost all of them were discharged with follow-up recommendations by the attending physician. Most of the episodes occurred during opening hours of primary healthcare centers.
Does neuromuscular exercise training improve proprioception in ankle lateral ligament injury among athletes? Systematic review and meta-analysis
Authors: Kalirtahinam Deivendran , Ismail Mohamed Saat , Singh Taran Singh Pall , Saha Soumendra , Hashim Hairul Anuar
Published: January 2017

DOI: 10.15448/1980-6108.2017.1.25082Aims: The prevalence rate of ankle complexities is increasing at a constant rate among athletes. This study aimed to systematically describe the facts and findings related to the effectiveness of training programs on proprioception among athletes suffering from ankle ligament injury.Methods: A literature search in online libraries (Google Scholar, PubMed, EBSCOhost, and ProQuest) using different search engines was conducted for the systematic review and meta-analysis. The common keywords included NEUROMUSCULAR, EXERCISE, TRAINING, PROPRIOCEPTION, and ATHLETES. Studies related to the topic, having relevant resources, and published within the past 10 years were used as inclusion criteria. Methodological quality was assessed through PEDro scale. A meta-analysis of the selected trials was conducted to assess the effectiveness of intervention. Results: Two hundred research articles were initially selected. After close scrutiny, 15 articles were included. Five moderate to excellent quality trials were selected, which involved 2,459 participants. It has been mainly identified that ankle sprain and its complications can be easily prevented with the help of training programs (five trials, relative risk: 0.69, 96%CI: 0.65-0.87). A statistically significant relationship was identified among athletes regarding the preventive impacts of training on proprioception. Conclusions: Preventive training programs were helpful for athletes in terms of proprioception, thus reducing the risk of ankle sprains.
Microstructure and Mechanical Behaviors of Nano-polycrystalline Diamonds Synthesized by Direct Conversion Sintering under HPHT
Authors: Sumiya Hitoshi , Irifune Tetsuo
Published: January 2017

High-purity nano-polycrystalline diamonds have been synthesized by direct conversion from graphite and various non-graphitic carbons under static high pressures and high temperatures. The polycrystalline diamond synthesized from graphite at ≥15 GPa and 2300-2600 °C has a mixed texture comprising a homogeneous fine structure (particle size: 10-30 nm, formed in a diffusion process) and a lamellar structure (formed in a martensitic process), and has a very high Knoop hardness of 120-145 GPa. In contrast, the polycrystalline diamonds made from the non-graphitic carbons at ≥15 GPa and 1600-2000 °C have a single texture consisting of a very fine homogeneous structure (5-10 nm, formed in a diffusion process) without a lamellar structure. The hardness values of the nano-polycrystalline diamonds made from non-graphitic carbons (70-90 GPa) are significantly lower than that of polycrystalline diamond made from graphite. The investigation of the microstructure beneath the indentation of these nano-polycrystalline diamonds revealed that the existence of the lamellar structure and the bonding strength of the grain boundary have a decisive effect on the hardness.
TEKNIK PENANGKAPAN IKAN MEMAKAI BRANJANG (ANCO) DI RAWA PENING, JAWA TENGAH
Authors: Sukandi Undang , Taryana Nana
Published: January 2017

Abstrak bisa dilihat di Lampiran
TEKNIK PENGOLAHAN DASAR (POSTPROSESSING) DATA AKUSTIK SPLIT BEAM UNTUK PENDUGAAN STOK IKAN
Authors: Sudjianto Sudjianto
Published: January 2017

Abstrak bisa dilihat di Lampiran
TEKNIK PENANGKAPAN DAN PENGOPERASIAN ALAT PANCING TUNA LONGLINE UNTUK MENANGKAP IKAN TUNA DI PERAIRAN SELATAN JAWA
Authors: Sawon Sawon
Published: January 2017

Abstrak bisa dilihat di Lampiran
DEPRESIJOS SIMPTOMŲ PAPLITIMAS TARP 3–5 STADIJŲ LĖTINE INKSTŲ
LIGA SERGANČIŲ PACIENTŲ
Authors: Markevičiūtė Mantė , Matusevičiūtė Audronė , Dlugauskas Edgaras , Danilevičiūtė Vita , Rimševičius Laurynas
Published: January 2017

Reikšminiai žodžiai: depresija, lėtinė inkstų liga.
Depresija yra viena dažniausių psichiatrinių ligų tarp pacientų, sergančių lėtine inkstų liga (LIL). Pastebėta, kad sergančiųjų
LIL depresijos simptomai yra susiję su prastesne gyvenimo kokybe, ilgesne hospitalizacijos trukme, greitesne dializės terapijos
pradžia bei padidėjusia mirties rizika. Norint išanalizuoti depresijos simptomų pasireiškimą, Vilniaus universiteto ligoninės
Santariškių klinikos (VUL SK) Nefrologijos centre atliktas skerspjūvio tyrimas. Įtraukti 132 pacientai, sergantys 3–5 stadijos
LIL. Tiriamieji įvertinti pagal Hamiltono depresijos skalę (HAM-D), surinkti duomenys apie LIL stadiją ir etiologiją, vedybinę
padėtį, darbo pobūdį, išsilavinimą, žalingus įpročius, fizinį aktyvumą, streso įveikos strategiją, demografiniai duomenys.
Statistinė duomenų analizė atlikta „Microsoft Excel“. 70 (53 proc.) apklaustų pacientų surinko lengvą depresiją atspindinčius
balus. Moterys (p = 0,0001), ≥ 80 m. (p = 0,03), ūkininkai (p = 0,009), taikantys į jausmus orientuotą įveikos strategiją (p =
0,04), surinko daugiau HAM-D balų, o susituokusieji (p = 0,015), sergantys IgA nefropatija (p = 0,49), užimantys aukštas
pareigas darbe (p = 0,0003) – mažiau. Dėl dažnai pasireiškiančių depresijos simptomų sergantiesiems lėtine inkstų liga rekomenduojame
rutinišką depresijos simptomų ištyrimą ir ankstyvą gydymą.
GLOMERULONEFRITŲ IMUNOSUPRESINIO GYDYMO KOMPLIKACIJOS
Authors: Tytmonas Evaldas , Vinikovas Artūras , Mačionienė Ernesta , Miglinas Marius , Rimševičius Laurynas
Published: January 2017

Reikšminiai žodžiai: imunosupresiniai vaistai, glukokortikosteroidai, glomerulonefritai, indukcinė imunosupresija, infekcinės
komplikacijos.
Įžanga. Glomerulonefritai – heterogeninė inkstų ligų grupė, kuriai būdingas ūmus arba lėtinis autoimuninės kilmės inkstų
pažeidimas, pasireiškiantis izoliuotu inkstų pažeidimu arba kaip komplikacija sergant sisteminėmis ligomis (sistemine raudonąja
vilklige, vaskulitu ir kt.). Glomerulonefritams gydyti skiriama imunosupresinių vaistų. Jatrogeninės komplikacijos
skiriant imunosupresantus dažnos ir įvairios.
Darbo tikslas. Ištirti imunosupresinio gydymo sukeltą komplikacijų paplitimą 12 mėnesių laikotarpiu, palyginti komplikacijų
dažnį skirtingose gydymo schemų ir amžiaus pacientų grupėse bei įvertinti gydymo efektyvumą remiantis laboratoriniais
kriterijais.
Tyrimo medžiaga ir metodai. Retrospektyvinio tyrimo metu buvo analizuotos Vilniaus universiteto ligoninės Santariškių klinikų
Nefrologijos centre 2004–2016 m. gydytų pacientų ligos istorijos. Į tyrimą įtraukti pacientai, kuriems autoimuninė inkstų
liga histologinio tyrimo metu nustatyta pirmą kartą ir paskirtas pradinis imunosupresinis gydymas. Tyrimo metu surinkti
duomenys apdoroti SPSS 22.0 programa, taikant porinį (paired) t-testą ir skaičiuojant galimybių santykį.
Rezultatai. Tyrimo imtį sudaro 87 pacientai, kurių amžiaus vidurkis 46,41 m. (± 16,49). Komplikacijos išsivystė 35 pacientams
(41,2 proc. pacientų), 52 pacientai (59,8 proc.) neturėjo komplikacijų per 12 mėnesių. 39 pacientams taikyta pulsinė
terapija: 15 pacientų skirtas metilprednizolonas, 12 metilprednizolonas ir ciklofosfamidas, 12 tik ciklofosfamidas. Iš 39 tiriamųjų
komplikacijos išsivystė 23 pacientams – 65,71 proc. Skiriant metilprednizolono pulsinę terapiją, komplikacijų pastebėta
7 iš 15 pacientų (46,66 proc.), metilprednizoloną ir ciklofosfamidą – 10 iš 12 pacientų (83,33%), tik ciklofosfamidą – 6 iš
12 (50 proc.). Skiriant indukcinę terapiją, komplikacijų atsiradimo rizika per pirmą mėnesį yra net 18,4 karto didesnė nei jos
neskiriant, per 3 mėnesius atitinkamai 3,86 karto didesnė, per 6 mėnesius atitinkamai 6,05 karto didesnė, o per 12 mėnesių
atitinkamai 5,8 karto didesnė tikimybė įvykti komplikacijai. Vertinant komplikacijų skaičių skirtingose amžiaus grupėse,
daugiausia komplikacijų įvyko 46-65 ir vyresnių nei 65 metų tiriamųjų grupėse atitinkamai 16 (61,54 proc.) ir 11 (68,75
proc.), komplikacijų skaičius iki 46 metų amžiaus grupėse buvo mažesnis nei 50 proc.
Išvados. Pulsinė terapija padidina komplikacijų išsivystymo riziką iki 18,4 karto pirmą gydymo mėnesį, padidėjusi rizika
išlieka visus metus. Daugiausia komplikacijų pasireiškė, kai indukcinei terapijai buvo skiriamas metilprednizolono ir ciklofosfamido
derinys. Vyresniame amžiuje dažniau nustatyta gydymo sąlygotų komplikacijų.
KLAIDINGAI TEIGIAMAS ŽMOGAUS IMUNODEFICITO VIRUSO TESTAS –
AR TAI KLIŪTIS INKSTO TRANSPLANTACIJAI?
Authors: Pavinič Jelena , Rimševičius Laurynas , Miglinas Marius
Published: January 2017

Reikšminiai žodžiai: inksto transplantacija, žmogaus imunodeficito virusas.
Į Vilniaus universiteto ligoninės Santariškių klinikų Nefrologijos ir inkstų transplantacijos skyrių atvyko 52 metų recipientė
inksto transplantacijai iš kadaverinio donoro. Atliekant potencialaus recipiento ištyrimą prieš inksto transplantaciją, rasta teigiama
žmogaus imunodeficito viruso (ŽIV) reakcija. Nustatant ŽIV p24 antigeną ir antikūnus prieš ŽIV 1 ir 2 tipą (Combo
metodas), reakcija buvo stipriai teigiama, tačiau papildomai tiriant ŽIV antigenus imunofermentinės analizės (IFA) metodu,
gautas neigiamas atsakymas. Padaryta prielaida, kad klaidingai teigiama reakcija pasireiškė dėl autoantikūnų, būdingų sisteminei
raudonajai vilkligei. Taip pat klaidingai teigiami ŽIV tyrimai gali pasitaikyti tarp pacientų, sergančių reumatoidiniu
artritu, virusiniais hepatitais, įvairiomis onkologinėmis, piktybinėmis hematologinėmis ir autoimuninėmis ligomis. Siekiant
užtikrinti tinkamą gydymą, reikiamu laiku rekomenduojamas atidus ir etapinis pacientų ištyrimas esant teigiamai ŽIV reakcijai.
INTEGRUOTAS POŽIŪRIS Į VAIKŲ ATOPINIO DERMATITO RAIŠKĄ: PSICHOSOMATINIS ASPEKTAS IR SĄSAJOS SU EMOCINIŲ SUNKUMŲ PATYRIMU
Authors: Kerzaitė Ieva , Ėmužytė Regina , Kinčinienė Odeta , Bieliauskaitė Rasa
Published: January 2017

Reikšminiai žodžiai: vaikai, atopinis dermatitas, emociniai sunkumai, somatizacija. Darbo tikslas. Pristatyti integruotą požiūrį į vaikų atopinį dermatitą, apimant psichosomatinį ligos aspektą. Atopinis dermatitas – lėtinė odos liga, kuri siejama su įvairiais psichikoje vykstančiais procesais. Apžvelgiant šiuolaikinę literatūrą ir tyrimus, atliktus šia tema, atsiskleidžia atopinio dermatito daugialypiškumas, o tai tampa argumentu tyrinėti ligą psichosocialiniame kontekste. Tai leidžia geriau suprasti sergančiojo emocinę būseną ir psichinius procesus, kurie taip pat atlieka svarbų vaidmenį ligos raidoje. Moksliniai tyrimai minėtomis kryptimis galėtų tapti vertingu indėliu, kad būtų geriau suprantami atopiniu dermatitu sergančio vaiko poreikiai ir būtų organizuojama veiksmingesnė kompleksinė sergančiojo priežiūra, integruojant ir psichologinę pagalbą.
VISCERALINĖS ANEURIZMOS: LITERATŪROS APŽVALGA
Authors: Kvietkauskas Ramūnas
Published: January 2017

Reikšminiai žodžiai: visceralinių arterijų aneurizmos, visceralinės aneurizmos, aneurizmos plyšimas. Straipsnyje pateikiama visceralinių aneurizmų literatūros apžvalga. Iki šiol literatūroje apie šią patologiją publikuota per 4 000 straipsnių. Pirmasis visceralinę aneurizmą aprašė prancūzas Beaussiers 1770 metais. Visceralinėmis aneurizmomis vadinamos pilvinio kamieno, viršutinės ir apatinės pasaito, inkstų arterijų ir jų šakų aneurizmos. Jų sutinkama ne daugiau kaip 2 proc. populiacijos. Visceralinės aneurizmos skirstomos į tikras visceralines aneurizmas ir pseudoaneurizmas. Pastarosios aptinkamos dvigubai dažniau nei tikros visceralinės aneurizmos. Dažniausiai tikrosios aneurizmos susiformuoja dėl aterosklerozės, fibromuskulinės displazijos arba traumos, o pseudoaneurizmas dažniausiai sukelia pankreatitai. Pagal klinikinę stadiją skiriamos asimptominės, simptominės ir plyšusios visceralinės aneurizmos. Pastarosios pasižymi ypač dideliu mirtingumu. Visceralinės aneurizmos dažniausiai pažeidžia blužnies arterijas, rečiau – kepenų, inkstų, ypač retai – kitas visceralines arterijas. Pagrindiniai diagnostikos iššūkiai – labai įvairi ir nespecifinė visceralinių aneurizmų klinika. Pagrindinės diagnostikos naujovės – didesnės raiškos ir erdvinės vaizdinių tyrimų atmainos. Planinis invazinis gydymas taikytinas, jei visceralinių aneurizmų diametras ≥ 2 cm, taip pat kai kurių išimčių atvejais – nepriklausomai nuo aneurizmos dydžio. Esant simptominėms aneurizmoms, intervencija turi būti atliekama neatidėliotinai, o plyšusių atvejais – skubiai. Minimaliai invaziniai gydymo metodai pamažu tampa pagrindiniai gydant visceralines aneurizmas. Ypač gerų rezultatų ateityje tikimasi gydant aneurizmas srovę nukreipiančiais stentais, kai jie taps prieinamesni.
STUDENTŲ PSICHOEMOCINĖS BŪKLĖS IR MIEGO KOKYBĖS SĄSAJOS
Authors: Mikaliūkštienė Aldona , Gendvilaitė Vilija , Kalibatienė Danutė
Published: January 2017

Vilniaus miesto klinikinė ligoninė
HIGIENINĖ-EPIDEMIOLOGINĖ INTERVENCINIŲ PROCEDŪRŲ SAUGA SLAUGOS PRAKTIKOJE
Authors: Gierasimovič Zita , Mikaliūkštienė Aldona , Kalibatienė Danutė
Published: January 2017

Reikšminiai žodžiai: intervencinių procedūrų higieninė sauga, slaugos paslaugos, rankų higiena, mikrobinė tarša. Tikslas. Ištirti, kaip laikomasi slaugos intervencinių procedūrų higieninės-epidemiologinės saugos taisyklių. Tyrimo medžiaga ir metodai. Tyrimas atliktas 2012–2014 metais vienoje Vilniaus ligoninėje. Tiriamąją grupę sudarė 272 slaugytojai, atliekantys pacientams intervencines slaugos procedūras, dirbantys reanimacijos ir intensyviosios terapijos, chirurgijos ir vidaus ligų skyriuose. Intervencinių procedūrų higieninės-epidemiologinės saugos vertinimas atliktas stebėjimo metodu remiantis Lietuvos higienos norma „Sveikatos priežiūros įstaigos. Infekcijų kontrolės reikalavimai (2012)“. Statistinė duomenų analizė. Tyrimo duomenys analizuoti „IBM SPSS Statistics 19.0“ programa. Taikyti aprašomosios statistikos metodai. Apskaičiuotos imčių charakteristikos: absoliutus skaičius (n), procentas (proc.), vidurkis, mediana. Skirtumai tarp skyrių buvo vertinami naudojant Pearsono chi-kvadrato (χ²) kriterijų. Rodikliai vertinti kaip statistiškai patikimi, kai p reikšmė ne didesnė kaip 0,05 (p ≤ 0,05), ir daroma išvada, kad skirtumai yra statistiškai reikšmingi. Rezultatai ir išvados. Visose slaugytojų profesinės patirties (metais) grupėse su rankų higiena susijusių klaidų skaičius kasmet mažėjo. 2014 m., palyginti su 2012 m., klaidų sumažėjo dvigubai. Iki 10-ties metų profesinės veiklos grupėje klaidų skaičius nuo 15,9 proc. sumažėjo iki 8,1 proc. (χ2 = 11,92; p = 0,003). Intervencinių procedūrų metu labai sumažėjo higieninės saugos klaidų (χ2 = 30,94; p < 0,001) vertinant darbo drabužių rankovių ilgį (χ2 = 30,94; p < 0,001); vertinant rankų papuošalų nešiojimą (χ2 = 142,55; p < 0,0001). Labai pagerėjo bendrieji rankų higienos įgūdžiai prieš intervencines procedūras (p < 0,0001). Dauguma tiriamųjų buvo susipažinę su rankų higienos rašytinėmis taisyklėmis ir pripažino, kad vaizdinė rankų plovimo ir antiseptikos metodinė medžiaga ir rankų higienos taisyklių išmanymas gerina rankų higienos įgūdžius.
MOTYVAVIMO POKALBIO KONSULTACIJŲ EFEKTYVUMAS KEIČIANT SĄNARIŲ LIGOMIS SERGANČIŲJŲ SU SVEIKATA SUSIJUSĮ ELGESĮ IR DIDINANT JŲ SAVIVEIKSMINGUMĄ REABILITACIJOS LAIKOTARPIU
Authors: Alčiauskaitė Laura , Šinkariova Liuda , Zajančkauskaitė-Staskevičienė Loreta , Misiūnienė Jurga , Petrolienė Raimonda
Published: January 2017

Reikšminiai žodžiai: motyvavimo pokalbis, sveikatai žalingas elgesys, saviveiksmingumas. Sveikatai palankaus elgesio rekomendacijų laikymasis palengvina sergančiųjų sąnarių ligomis sveikimą. Tačiau patys pacientai dažnai stokoja vidinės motyvacijos keisti įprastą elgesį. Sveikatai žalingas elgesys gali būti koreguojamas naudojant motyvavimo pokalbį, kuriuo siekiama sustiprinti asmens saviveiksmingumą ir vidinę motyvaciją keisti savo elgesį. Tyrimo tikslas. Įvertinti motyvavimo pokalbio konsultacijų efektyvumą keičiant sąnarių ligomis sergančiųjų su sveikata susijusį elgesį ir didinant jų saviveiksmingumą. Tyrimo medžiaga ir metodai. Tyrimo metodas – kvazieksperimentas. Tyrime dalyvavo 126 Abromiškių reabilitacijos ligoninės artrologijos-traumatologijos skyriaus pacientai (37 vyrai, 89 moterys), sergantys sąnarių ligomis. Iš jų 66 buvo priskirti poveikio grupei, o 60 – kontrolinei grupei. Tiriamųjų amžius svyravo nuo 21 iki 75 metų (vidurkis – 57,69 ± 10,52 m.). Poveikio grupei per gydymosi laikotarpį buvo taikomos 1–4 motyvavimo pokalbio konsultacijos, jų elgesio ir saviveiksmingumo pokyčiai buvo lyginami su kontroline grupe. Su sveikata susijusio elgesio (alkoholio vartojimo, rūkymo, fizinio aktyvumo, mitybos) pokyčiams išmatuoti naudotas pasirengimo pokyčiui klausimynas („Readiness to Change Questionnaire“, 1992), sudarytas pagal transteorinį pokyčių modelį ir atspindintis tris pokyčių stadijas: nesusimąstymo, mąstymo ir veiksmo. Saviveiksmingumui įvertinti naudotas sveikatos saviveiksmingumo klausimynas. Tiek poveikio, tiek kontrolinės grupės pacientai klausimynus pildė du kartus – gydymo pradžioje ir pabaigoje. Tyrimo rezultatai. Nustatyta, jog po motyvavimo pokalbio konsultacijų poveikio grupės tiriamieji pasistūmėjo aukštesnės pasirengimo keistis stadijos link vertinant fizinio aktyvumo ir rūkymo įpročius. Kontrolinės grupės tiriamieji taip pat perėjo į aukštesnę pasirengimo keisti fizinį aktyvumą stadiją reabilitacijos pabaigoje. Po motyvavimo pokalbio konsultacijų poveikio grupės tiriamųjų sveikatos saviveiksmingumo įverčiai padidėjo, palyginti su pirmąja apklausa. Kontrolinės grupės sveikatos saviveiksmingumas nesikeitė. Išvados. Motyvavimo pokalbio konsultacijos padeda sergantiesiems sąnarių ligomis reabilitacijos metu susimąstyti ir imtis veiksmų keičiant rūkymo ir fizinio aktyvumo įpročius bei didina jų sveikatos saviveiksmingumą.
TRANSFUSION-RELATED ACUTE LUNG INJURY IN MULTIPLE TRAUMA PATIENT: SUCCESSFUL USE OF EXTRACORPOREAL MEMBRANE OXYGENATION
Authors: Karosas Vytautas , Bakšienė Rytė , Šipylaitė Jūratė , Klimašauskas Andrius , Kėkštas Gintautas
Published: January 2017

Su transfuzija susijęs ūminis plaučių pažeidimas yra pagrindinė sergamumo ir mirštamumo priežastis tarp su transfuzijomis susijusių reakcijų. Sindromas pasireiškia po kraujo plazmos turinčių komponentų transfuzijos. Straipsnyje aprašomas klinikinis atvejis apie su transfuzija susijusį plaučių pažeidimą ligoniui po politraumos. Gydant buvo sėkmingai pritaikytas ekstrakorporinės membraninės oskigenacijos metodas.
The Effectiveness of an Online Training to Disseminate an Evidence-Based Intervention to Address Pediatric Secondhand Smoke Exposure
Authors: Marbin Jyothi , Purdy Cindy Nelson , Tebb Kathleen
Published: January 2017

This article was migrated. The article was not marked as recommended. Background: There is a significant lag between research on evidence-based practices (EBP) and adoption into clinical practice. A critical step is to train clinics on EBPs. There is limited research on the efficacy of online trainings on EBP implementation in clinic settings. Methods: A cluster randomized control trial of 13 pediatric practices compared the acceptability and impact of an online versus in-person EBP training to reduce secondhand smoke exposure (SHSE) in children. A retrospective pre-post design was used to assess practice performance on specific metrics of the SHSE intervention. Results: 13 clinics were randomized to receive the online (n=5) or in-person training (n=8). Both groups reported high knowledge and self-efficacy after the trainings, though these were significantly higher for the in-person training group. Both groups showed significant pre-post improvements in implementing key components of the intervention. When analyzed by training group, there were significant improvements in some but not all of the metrics. Conclusion: Despite preferences for the in-person training, the online module is acceptable to providers, and improves self-efficacy and implementation of some aspects of a SHSE intervention. Given the challenges and high costs of in-person trainings, carefully designed online modules represent a promising approach to disseminate EBPs.
Mixed Responses to Systemic Therapy Revealed Potential Genetic Heterogeneity and Poor Survival in Patients with Non-Small Cell Lung Cancer
Authors: Dong Zhong-Yi , Zhai Hao-Ran , Hou Qing-Yi , Su Jian , Liu Si-Yang , Yan Hong-Hong , Li Yang-Si , Chen Zhi-Yong , Zhong Wen-Zhao , Wu Yi-Long
Published: January 2017

Background

A subset of patients with non-small cell lung cancer (NSCLC) fosters mixed responses (MRs) to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) or chemotherapy. However, little is known about the clinical and molecular features or the prognostic significance and potential mechanisms.

Methods

The records of 246 consecutive patients with NSCLC receiving single-line chemotherapy or TKI treatment and who were assessed by baseline and interim positron emission tomography/computed tomography scans were collected retrospectively. The clinicopathological correlations of the MR were analyzed, and a multivariate analysis was performed to explore the prognostic significance of MR.

Results

The overall incidence of MR to systemic therapy was 21.5% (53/246) and predominated in patients with stage IIIB–IV, EGFR mutations and those who received TKI therapy (p < .05). Subgroup analyses based on MR classification (efficacious versus inefficacious) showed significant differences in subsequent treatment between the two groups (p < .001) and preferable progression-free survival (PFS) and overall survival (OS) in the efficacious MR group. Multivariate analyses demonstrated that the presence of MR was an independent unfavorable prognostic factor for PFS (hazard ratio [HR], 1.474; 95% confidence interval [CI], 1.018–2.134; p = .040) and OS (HR, 1.849; 95% CI, 1.190–2.871; p = .006) in patients with NSCLC. Induced by former systemic therapy, there were more T790M (18%), concomitant EGFR mutations (15%), and changes to EGFR wild type (19%) in the MR group among patients with EGFR mutations, which indicated higher incidence of genetic heterogeneity.

Conclusion

MR was not a rare event in patients with NSCLC and tended to occur in those with advanced lung adenocarcinoma treated with a TKI. MR may result from genetic heterogeneity and is an unfavorable prognostic factor for survival. Further studies are imperative to explore subsequent treatment strategies.
Hydrodynamic Isotonic Fluid Delivery Ameliorates Moderate-to-Severe Ischemia-Reperfusion Injury in Rat Kidneys
Authors: Collett Jason A. , Corridon Peter R. , Mehrotra Purvi , Kolb Alexander L. , Rhodes George J. , Miller Caroline A. , Molitoris Bruce A. , Pennington Janice G. , Sandoval Ruben M. , Atkinson Simon J. , Campos-Bilderback Silvia B. , Basile David P. , Bacallao Robert L.
Published: January 2017

Highly aerobic organs like the kidney are innately susceptible to ischemia-reperfusion (I/R) injury, which can originate from sources including myocardial infarction, renal trauma, and transplant. Therapy is mainly supportive and depends on the cause(s) of damage. In the absence of hypervolemia, intravenous fluid delivery is frequently the first course of treatment but does not reverse established AKI. Evidence suggests that disrupting leukocyte adhesion may prevent the impairment of renal microvascular perfusion and the heightened inflammatory response that exacerbate ischemic renal injury. We investigated the therapeutic potential of hydrodynamic isotonic fluid delivery (HIFD) to the left renal vein 24 hours after inducing moderate-to-severe unilateral IRI in rats. HIFD significantly increased hydrostatic pressure within the renal vein. When conducted after established AKI, 24 hours after I/R injury, HIFD produced substantial and statistically significant decreases in serum creatinine levels compared with levels in animals given an equivalent volume of saline via peripheral infusion (P<0.05). Intravital confocal microscopy performed immediately after HIFD showed improved microvascular perfusion. Notably, HIFD also resulted in immediate enhancement of parenchymal labeling with the fluorescent dye Hoechst 33342. HIFD also associated with a significant reduction in the accumulation of renal leukocytes, including proinflammatory T cells. Additionally, HIFD significantly reduced peritubular capillary erythrocyte congestion and improved histologic scores of tubular injury 4 days after IRI. Taken together, these results indicate that HIFD performed after establishment of AKI rapidly restores microvascular perfusion and small molecule accessibility, with improvement in overall renal function.
Fishing gears and methods in the Chalan Beel, Bangladesh
Authors: Sultana Nahid , Islam M Nazrul
Published: January 2017

Present study on fishing gears and methods in the Chalan Beel was conducted during the period of July 2011 to June 2014. The Chalan Beel is the large network of fluvial waters body that harbors rich ichthyofaunal diversity. Most of the fishing methods of the Chalan Beel are primitive, based on indigenous traditional knowledge and well suited to turbulent nature of the streams. In this study thirty fishing methods and gears have been documented and classified into five categories- fishing nets, traps, wounding gears, hooks and lines, and others. Many of these were harmful to fishes as well as aquatic biodiversity. Effective measurements are required to make proper use of the Chalan Beel.
Eutropiichthys vacha (Hamilton, 1822), a threatened fish of Indian subcontinent
Authors: Gupta Sandipan , Banerjee Samir
Published: January 2017

Eutropiichthys vacha (Batchwa vacha) is a freshwater catfish species having high economic value. It is a very popular table fish among the consumers due to high nutritional value and taste. Just recently small specimens of this species have also made their entry in ornamental fish markets. Recently due to number of reasons, populations of this fish species are facing the threat of extinction. It has already been documented as Endangered in India and Critically Endangered in Bangladesh. The present report has been prepared to summarize the information available on different aspects of this threatened fish species as well as to point out the possible measures that should be considered for its conservation.
Investigation on changing pattern of health status of juvenile Hypophthalmichthys molitrix from farming systems in Bangladesh
Authors: Gosh Kamal , Ahmed Gias Uddin , Akter Mst Nahid
Published: January 2017

An experiment was carried out to investigate the health status of Hypophthalmichthys molitrix among three different fish farms at Mymensingh district of Bangladesh. Fish sampling and water quality parameters were collected on a monthly basis. Samples of skin, muscle, gills, liver and kidney were examined through histological technique. Results from water quality parameters suggested that water temperature had a distinct effect on fish health of H. molitrix, which was mostly evident during the colder months. Infectious symptoms were usually evident in July to October and the severity of pathology was increased in November and December. These were evident from their clinical signs that include scale loss, haemorrhagic lesion, and reddish spots or from their histopathological symptoms such as necrosis, pyknosis, inflammation, haemorrhage, hypertrophy, missing of gill lamellae, vacuums, tubular and pillar cells degeneration, inflammation, clubbing, and suspected bacterial colonies. Results suggest that the health condition of the fishes from BAU fish farm was the best over the other two farms, whereas Government fish farm followed by NGO fish farm were severely affected with EUS, protozoan and bacterial infection. Moreover, internal organs like liver and kidney were more affected than skin, muscle and gills.
Plautinismos e Suassunismos em O santo e a porca
Authors: Cardoso Isabella Tardin , Santos Sônia Aparecida dos
Published: January 2017

O presente artigo tem como objetivo ler a comédia de Suassuna por meio de um olhar de plautinistas. A intenção aqui não será apontar todos os pontos em comum entre O santo e a porca e seu modelo plautino, a Aululária, mas sim discutir alguns dos mais importantes deles, na medida em que nos auxiliem em duas questões. De um lado, pretende-se evidenciar alguns efeitos dramáticos específicos, resultantes da mescla de motivos brasileiros com os da comédia romana. De outro lado, levando em conta o fato de que também Plauto imitava comédias gregas (adaptando-as, dentro do gênero da fabula palliata, ao público romano coevo), o objetivo central do artigo é observar até que ponto algumas características do texto e da performance atribuídas pela crítica moderna ao dramaturgo romano também se apresentam na peça brasileira, e, em caso positivo, com que efeito. Ao demonstrar que Suassuna emula também o modus imitandi de Plauto, nossa expectativa é de que esta investigação da intertextualidade entre as obras, considerando o modo como Suassuna sublinha ou mascara sua inspiração plautina, possa contribuir para lançar luzes sobre sua própria poética “nordestina”, que envolve a questão do engano cômico e sua relação com a ilusão dramática.
Heroísmo ma non troppo: o paradigma deficitário de Quéreas e Jasão
Authors: Barbieri Pedro
Published: January 2017

Adotando o argumento de um processo de transformação pelo qual Quéreas passa ao demonstrar um caráter mais forte nos dois últimos livros de Quéreas e Calírroe, pretendo explorar aqui os momentos de insegurança e hesitação que esse personagem apresenta nos seis primeiros livros do romance e como isso se encaixa no seu programa heroico. Para tanto, como termo de comparação, apresento a já bastante explorada figuração do êthos de Jasão e busco encontrar nele alguns germes da conduta de Quéreas, de modo a rastrear uma espécie de árvore genealógica desse tipo de caracterização, em alguns pontos avesso ao código tradicional homérico.
A Polifonia do Platonismo: Alcínoo e Máximo de Tiro
Authors: Brandão Bernardo Lins
Published: January 2017

Se, nos dias de hoje, na tradição analítica, o principal atributo da filosofia é o argumento lógico, na Antiguidade, ela podia abarcar a retórica e envolver um modo distinto de vida. Neste artigo, analiso dois conceitos de filosofia, apresentados por dois filosófos medioplatônicos: Alcínoo, autor do Didascálicos, e Máximo de Tiro, que escreveu as Dialéxeis. Como integrantes de um mesmo movimento filosófico, a visão deles é, em certos aspectos, similar: ambos consideram a filosofia como uma forma de conhecimento das coisas humanas e divinas que possui consequências éticas. Mas, se para Alcínoo o modo de vida filosófico é o theoretikós bíos, o ideal de Máximo é o do orador filosófico, o que é possível para ele por causa de sua noção da polifonia da filosofia.
Desejo e fúria de Ovídio pelas tabelas: Amores 1.11 e 1.12
Authors: Vieira Brunno Vinícius Gonçalves
Published: January 2017

Apresenta-se, neste artigo, a tradução do díptico (Amores 1.11 e 1.12) precedida de uma introdução em que o tradutor busca apresentar as motivações práticas e teóricas subjacentes à sua execução. Desenvolve-se uma breve reflexão sobre a duplicidade e a desigualdade tanto dos versos quanto dos personagens que vivem duas diferentes situações de uma fábula amorosa. O díptico oferece dois lances opostos de uma tentativa de amor, sua esperança e seu fracasso. Desejava o poeta se declarar. Desejava o encontro. Desejava Amor em seu sentido carnal (1.11), mas recebe a negativa, caindo em fúria, não contra a amada, mas contra as dúplices tabuinhas (1.12), sendo essas últimas mais uma metonímia da dubiedade do gênero elegíaco como praticado por Ovídio. A tradução, em uma estrofe portuguesa composta por dois decassílabos seguidos de um hexassílabo, procura replicar poeticamente alguns aspectos sonoros, sintáticos e semânticos percebidos no texto de partida.
Letras Clássicas na Escola: sobre “a utilidade do inútil”
Authors: Miotti Charlene Martins
Published: January 2017

Em seu mais recente ensaio, A utilidade do inútil (Les Belles-Lettres, 2013; Zahar, 2016), Nuccio Ordine problematiza a chamada “ditadura do proveito” na educação, reacendendo uma polêmica há muito conhecida entre os professores da área de Estudos Clássicos. Este trabalho apresenta alguns materiais didáticos oriundos do projeto “Letras Clássicas na Escola”, desenvolvido na Universidade Federal de Juiz de Fora (UFJF) e financiado pela Fundação de Apoio à Pesquisa do Estado de Minas Gerais (FAPEMIG), que se destinam a atividades extracurriculares nas escolas básicas brasileiras, entre eles, o jogo de tabuleiro da Odisseia e a Aventura-Solo As Metamorfoses. O pressuposto comum entre o manifesto de Nuccio Ordine e o referido projeto está na concepção do sistema educacional (incluídas aí as universidades) como espaço de formação humanista, onde a leitura e a cultura, imunes a qualquer expectativa imediatista de serventia, representam “um antídoto contra a barbárie do útil, que chegou a corromper inclusive nossas relações sociais e nossos afetos íntimos”.
Declamação e Comédia Nova: estereótipos cômicos de velho avarento em exercícios retóricos gregos
Authors: Silva Barbara da Costa
Published: January 2017

Neste artigo, pretendo realçar alguns pontos de conexão entre a caracterização do velho avarento em duas declamações gregas de Libânio e de Corício e o modo como tal personagem é representada nas Comédias Novas, especialmente nas de Menandro. As semelhanças são abundantes e patentes. Há suficiente evidência para provar que Menandro foi um autor lido e emulado em círculos de estudo da oratória: inúmeros testimonia antigos, como Quintiliano e Dião Crisóstomo, confirmam tal afirmação. Nessa medida, este artigo investiga as razões que motivaram a alusão deliberada a Menandro nas declamações mencionadas.
A multiscale approach to assess geomorphological processes in a semiarid badland area (Ebro Depression, Spain)
Authors: Ferrer V. , Errea P. , Alonso E. , Nadal-Romero E. , Gómez-Gutiérrez A.
Published: January 2017

In this paper, three methods (Terrestrial Laser Scanner (TLS), terrestrial Structure from Motion photogrammetry (SfM) and aerial SfM photogrammetry with an Unmanned Aerial Vehicle (UAV)) were evaluated and compared to produce high resolution point clouds and Digital Elevation Models (DEMs) in a semiarid, complex badland area (Los Aguarales) with tourism activities. Geomorphological processes and dynamics were studied at different spatial scales. The preliminary results showed the possibilities of a multiscale approach, using various non-invasive techniques, to assess geomorphological processes. The high resolution of the point clouds, obtained with TLS and terrestrial SfM photogrammetry, allowed preliminary identification of numerous spatial details, although no relevant topographical changes were detected during a short, wet spring period (with rainfall of 200 mm). UAV images allowed work at larger scales (catchment), mapping piping features, and could be seen as a worthwhile tool for time-effective data acquisition from larger areas. The application of different technologies and a multiscale approach to generate high resolution DEMs is a useful technique when carrying out geomorphological studies in semiarid badland areas. However, long term studies will be necessary to verify the suitability of these techniques in such complex landscapes, and quantify topographical changes and erosion rates. Finally, the information obtained with these tools could be used to promote the study area as an interesting geomorphosite with opportunities for tourism.
Bayesian Inference for Single-cell Clustering and Imputing
Authors: Azizi Elham , Prabhakaran Sandhya , Carr Ambrose , Pe'er Dana
Published: January 2017

Single-cell RNA-seq gives access to gene expression measurements for thousands of cells, allowing discovery and characterization of cell types. However, the data is noise-prone due to experimental errors and cell type-specific biases. Current computational approaches for analyzing single-cell data involve a global normalization step which introduces incorrect biases and spurious noise and does not resolve missing data (dropouts). This can lead to misleading conclusions in downstream analyses. Moreover, a single normalization removes important cell type-specific information. We propose a data-driven model, BISCUIT, that iteratively normalizes and clusters cells, thereby separating noise from interesting biological signals. BISCUIT is a Bayesian probabilistic model that learns cell-specific parameters to intelligently drive normalization. This approach displays superior performance to global normalization followed by clustering in both synthetic and real single-cell data compared with previous methods, and allows easy interpretation and recovery of the underlying structure and cell types.
EDUCAÇÃO ESPECIAL/INCLUSIVA NO BRASIL: demandas contemporâneas
Authors: Oliveira Ivanilde Apoluceno de
Published: January 2017

Neste artigo analisamos as demandas que emergem do processo de implantação da política de inclusão na Educação Especial no Brasil.Demandas referentes a novos sujeitos; a formação e prática, que envolve o debatesobre o currículo, e o atendimento educacional na educação inclusiva. Este estudo tem por base pesquisas realizadas em municípios do Estado do Pará e,também, o levantamento bibliográfico sobre a educação inclusiva no Brasil, incluindo análise de documentos sobre a legislação referente à política da Educação Especial.O estudo aponta que há necessidade de se evidenciar as demandas, problematizar a política, que não atende as especificidades regionais, mas sobretudo, apontar pistas, caminhos teóricos e metodológicos para a inclusão escola e social do aluno público-alvo da Educação Especial.Palavras-chave: Educação Especial. Política de Inclusão. Demandas contemporâneas. SPECIAL EDUCATION / INCLUSIVE IN BRAZIL: conteporary demandsAbstract: In this article we analyze the emerging demands from the implementation process of inclusion policy on Special Education in Brazil. Demands related to new subjects; training and practice, evolving the debate oncurriculum, and educational services in inclusive education. This study is based on surveys conducted in municipalities in the State of Pará and, Also the literature on inclusive education in Brazil, including document analysis onlegislation referring to the Special Education policy. The study points out that there is need to highlight the demands, problematize politics, that does not meet specific regional characteristics, but above all, point out hints, theoretical and methodological approaches to include school and social of the Special Education student audience.Keywords: Special education. Inclusion Policy. Contemporary demands. EDUCACIÓN ESPECIAL/INCLUSIVA EN BRASIL: demandas contemporáneas Resumen: En este artículo analizamos las demandas que surgen del proceso de implementación de la política de inclusión en la Educación Especial en Brasil. Demandas relacionadas con nuevos sujetos, la formación y práctica, que implican el debate sobre el currículo y el atendimiento educativo en la educación inclusiva. Este estudio se basa en investigaciones realizadas en municipios del Estado de Pará y también la literatura sobre la educación inclusiva en Brasil, incluyendo el análisis de documentos de la legislación sobre la política de Educación Especial. El estudio señala que existe la necesidad de poner de relieve las demandas, cuestionar la política, que no cumple con las especificidades regionales, pero, sobre todo, señalar caminos, enfoques teóricos y metodológicos para la inclusión escolar y social del alumno público clave de la Educación Especial.Palabras clave: Educación Especial. Política de Inclusión. Demandas contemporáneas.
A socioeconomic study on pros and cons of SRI method of paddy cultivation in ormanjhi block of Ranchi district, Jharkhand
Authors: Agarwal Punit Kumar , Kumar Ajay
Published: January 2017

Rice is a staple food for more than half of the world’s population. World rice production nearly doubled since the 1960s to the 1980s, mainly due to the green revolution. A major issue with the traditional system of paddy production, particularly green revolution technology is input intensive and favors cash rich farmers. Increasing prices of agricultural inputs prevent poor farmers from completely adopting modern production technologies. Water demand by rice farmers were also continue increasing under such circumstances, any strategy that could produce higher rice yields with less water and less expenditure is the need of the day. Under such circumstances the system of rice intensification (SRI) method was suitable and followed by the farmers. System of rice intensification is a method for increasing the productivity of rice cultivation while at the same time reducing inputs, including seeds and fertilizers, and water requirements. The present study was conducted in Ormanjhi block of Ranchi district, to study the socio-economic profile of paddy growers, perception and constraints confronted by paddy growers under SRI method of paddy cultivation. Study revealed that the major constraints in SRI production were lack of awareness, scarcity of skilled labour, nursery management, and drudgery in cono-weeder uses. The major perception regarding SRI method of paddy cultivation were low demand of water, higher yield, remuneration from government, low seed requirement, low costs of input uses.
Major and micro nutrient status of rice-chickpea grown in soilsof Chhattisgarh Plain region of India
Authors: Kumar Awanish , Srivastava L. K. , Mishra V. N. , Banwasi Rakesh
Published: January 2017

The content of major and micronutrients and their availability to crop vary widely depending upon soil types, nature of crops, ecology and agro climatic variability. Study undertaken to assess the nutrients status of rice- chickpea grown areas of Chhattisgarh plain region of Chhattisgarh revealed that soil were low in available nitrogen and low to medium in available phosphorous and high in potassium status. Soils are deficient in micronutrients (Fe, Mn, Zn and Cu). This problem is aggravated by the fact that many modern cultivars of major crops are highly sensitive to low micronutrient levels. Available micronutrients were negligible in Fe, Mn and Cu, but Zn status 43 percent soils sample had deficit level. However, frequency distribution of micronutrients into various categories showed that large area in the state has potential to be deficient in future, which may respond to micronutrients applications. In order to understand the geographic distribution of available micronutrient content in soil of the state, soil micronutrient maps have been developed using GPS and GIS which will improve our understanding regarding nature and extent of micronutrients deficiencies and their response to crop growth and development. These maps and frequency distribution of available macro and micronutrient content in soils will be highly useful in assessing fields scale variability for developing site-specific nutrients management for better human and livestock health of Chhattisgarh plain region.
Supply chain optimization with variable demand by considering financial criteria and scenarios
Authors: Escobar John Willmer
Published: January 2017

This paper contemplates the supply chain design problem of a large-scale company by considering the maximization of the Net Present Value. In particular, the variability of the demand for each type of product at each customer zone has been estimated. As starting point, this paper considers an established supply chain for which the main problem is to determine the decisions regarding expansion of distribution centers. The problem is solved by using a mixed-integer linear programming model, which optimizes the different demand scenarios. The proposed methodology uses a scheme of optimization based on the generation of multiple demand scenarios of the supply network. The model is based on a real case taken from a multinational food company, which supplies to the Colombian and some international markets. The obtained results were compared with the equivalent present costs minimization scheme of the supply network, and showed the importance and efficiency of the proposed approach as an alternative for the supply chain design with stochastic parameters.