bluuebunny/crossref_metadata_2025 huggingface dataset:
Differentiating Between Epstein-Barr Virus–positive Lymphoid Neoplasm Relapse and Post-transplant Lymphoproliferative Disorder After Sex-mismatched Hematopoietic Stem Cell Transplantation
Authors: Kurashige Ryumei , Kurashige Masako , Okada Yosuke , Higuchi Kohei , Yuda Sayako , Hino Akihisa , Miyamura Takako , Ichii Michiko , Fukushima Kentaro , Honma Keiichiro , Takeuchi Makoto , Yokota Takafumi , Ishikawa Jun , Sawada Akihisa , Shibayama Hirohiko , Hosen Naoki , Morii Eiichi
Published: January 2024

After allogeneic hematopoietic stem cell transplantation (HSCT), accurate differentiation between donor-derived post-transplant lymphoproliferative disorder (PTLD) and relapse of recipient-derived lymphoproliferative disorder (LPD) is crucial for determining treatment. Conventional diagnostic approaches for PTLD include histopathological examination, flow cytometry, and chimerism analysis of bulk tumor tissue. However, these methods are inconclusive in cases in which the primary disease is an Epstein-Barr virus (EBV)–positive LPD and is of the same lineage as that of the post-HSCT LPD tumor cells. Particularly, in cases where the number of tumor cells in the tissue is low, it is difficult to determine the origin of tumor cells. In this study, we developed a new method to simultaneously detect signals using sex chromosome fluorescence in situ hybridization, immunofluorescence staining, and EBV-encoded small RNA in situ hybridization on a single section of formalin-fixed paraffin-embedded histopathological specimen. The utility of the method was validated using specimens from 6 cases of EBV-positive LPD after sex-mismatched HSCT that were previously difficult to diagnose, including Hodgkin lymphoma–like PTLD that developed after HSCT for Hodgkin lymphoma and recurrence of chronic active EBV infection. This method successfully preserved the histologic structure after staining and allowed accurate determination of tumor cell origin and lineage at the single-cell level, providing a definitive diagnosis in all cases. This method provides a powerful tool for the diagnosis of LPDs after sex-mismatched HSCT.
SMARCB1 (INI1) Deficient Tumours of the Uterine Cervix: Report of Two Cases, Including One Associated With an NTRK Fusion
Authors: Razack Rubina , Butt Jennifer L. , Hostein Isabelle , Velasco Valerie , Croce Sabrina , Olory Carel , Fu Lili , Foulkes William D. , McCluggage W. Glenn
Published: January 2024

Pathogenic variants (mutations) and other molecular events involving subunits of the SWItch/Sucrose Non-Fermentable chromatin remodelling complex are common in a wide variety of malignancies. Many of these neoplasms are characterized by undifferentiated morphology. They arise at a variety of sites in the female genital tract but have rarely been reported in the uterine cervix. We report 2 primary cervical neoplasms arising in young women (ages 28 and 29 yr) exhibiting loss of nuclear immunoreactivity with SMARCB1 (INI1). In one case, which had a mixture of epithelioid and spindle cells, molecular studies revealed no SMARCB1 pathogenic variant, but showed a SPECCL1::NTRK 3 fusion, in keeping with an NTRK fusion sarcoma. The second case exhibited rhabdoid morphology and molecular testing confirmed a SMARCB1 pathogenic variant (c.425 T>G:p.(Leu142Ter) which, interpreted in conjunction with the morphology and immunohistochemistry, resulted in classification as a proximal-type epithelioid sarcoma. To our knowledge, this is the first reported cervical neoplasm exhibiting a SMARCB1 pathogenic variant and the first NTRK fusion sarcoma showing SMARCB1 protein loss. We discuss the diagnostic challenges and complexities of the molecular findings.
Revisions after Trapeziometacarpal Joint Resection Arthroplasty: A Systematic Literature Review
Authors: Neumeister Sara , Hagert Elisabet , Chung Kevin C. , Farnebo Simon , Boeckstyns Michel , Herren Daniel B. ,   FaiTh Study Working Group, Marks Miriam
Published: January 2024

Background:

The aim of this systematic literature review was to describe current indications and interventions for revisions after trapeziometacarpal joint (TMJ) resection arthroplasty.

Methods:

The literature search was conducted by an experienced librarian in the MEDLINE, Embase, Cochrane Library, Web of Science, and Scopus databases. The authors included all articles that investigated any TMJ arthroplasty procedure in which the trapezium was completely resected and if any subsequent revision procedure including joint-related and soft-tissue operations was mentioned. Two independent reviewers selected the articles and were involved in data extraction.

Results:

Sixty-two articles reporting on 5284 operated thumbs and 434 revision operations were included. Twenty-four indications for revision and 31 revision techniques were extracted. Most revisions were performed because of subsidence/impingement of the first metacarpal bone (n = 194 thumbs) followed by unspecified pain (n = 53), metacarpophalangeal joint problems (n = 28), and scaphotrapezoidal osteoarthritis (n = 17). Eleven treatment strategies were found for subsidence/impingement of the first metacarpal, the most frequent being revision of the existing interposition using autologous tendon (n = 46) and soft-tissue interposition with distraction pinning (n = 28).

Conclusions:

There are a wide variety of indications and even more surgical techniques described in the literature to treat persisting or recurrent pain after TMJ resection arthroplasty. Currently, there is no uniform treatment guideline available on how to diagnose and treat such cases. Therefore, the results of this literature review will form the basis for a Delphi study aiming to develop recommendations for the diagnosis and treatment of persistent/recurrent pain after TMJ resection arthroplasty.
Mycotic Aneurysms: Uncommon Pathogens and Treatment Conundrums
Authors: Ravindra Akshatha , Naguthevar Santhanam , Kumar Deepak , Rajagopal Rengarajan , Khera Pushpinder Singh , Tak Vibhor , Ramankutty Neetha Thayil , Meena Durga Shankar , Midha Naresh , Bohra Gopal Krishana , Garg Mahendra Kumar
Published: January 2024

Introduction

Mycotic aneurysms, characterized by vessel wall dilation resulting from infections including bacteria, fungi, and viruses, are a rare yet severe consequence of systemic infections.These aneurysms, accounting for 0.6% of Western countries' aneurysms, carry a higher risk of rupture compared to uninfected conditions. While the femoral artery, aorta, and intracranial visceral arteries are commonly affected, pathogens causing mycotic aneurysms vary across regions. Diagnostic challenges arise from nonspecific symptoms such as fever, pulsatile mass, local discomfort, and arterial inflammation.

 

Materials & Methods:
The case series involves three patients diagnosed with mycotic aneurysms due to unusual pathogens. We describe each patient's clinical presentation, medical history, physical examination findings, laboratory results, imaging studies, and the diagnostic process leading to the identification of the causative pathogens.

Results

The first case depicts a 70-year-old male with a ruptured infra-renal abdominal aortic pseudoaneurysm caused by Salmonella Paratyphi A. The second case involves a 66-year-old male with a Streptococcus pneumoniae-associated descending thoracic aortic pseudoaneurysm. The third case pertains to a 70-year-old male with a ruptured descending thoracic aortic aneurysm into the esophagus due to Pseudomonas aeruginosa infection. Each case highlights unique clinical features, laboratory findings, imaging results, and the management approaches undertaken.

Conclusion

Mycotic aneurysms, stemming from infections involving diverse pathogens, pose diagnostic challenges due to their nonspecific symptoms. Early identification and intervention are essential to mitigate the severe complications associated with these aneurysms. The presented cases underscore the need for a comprehensive approach to diagnosis and management, ensuring optimal outcomes for patients affected by mycotic aneurysms.
pyngoST: fast, simultaneous and accurate multiple sequence typing of Neisseria gonorrhoeae genome collections
Authors: Sánchez-Busó Leonor , Sánchez-Serrano Andrea , Golparian Daniel , Unemo Magnus
Published: January 2024

Extensive gonococcal surveillance has been performed using molecular typing at global, regional, national and local levels. The three main genotyping schemes for this pathogen, multi-locus sequence typing (MLST),

Neisseria gonorrhoeae

multi-antigen sequence typing (NG-MAST) and

N. gonorrhoeae

sequence typing for antimicrobial resistance (NG-STAR), allow inter-laboratory and inter-study comparability and reproducibility and provide an approximation to the gonococcal population structure. With whole-genome sequencing (WGS), we obtain a substantially higher and more accurate discrimination between strains compared to previous molecular typing schemes. However, WGS remains unavailable or not affordable in many laboratories, and thus bioinformatic tools that allow the integration of data among laboratories with and without access to WGS are imperative for a joint effort to increase our understanding of global pathogen threats. Here, we present pyngoST, a command-line Python tool for fast, simultaneous and accurate sequence typing of

N. gonorrhoeae

from WGS assemblies. pyngoST integrates MLST, NG-MAST and NG-STAR, and can also designate NG-STAR clonal complexes, NG-MAST genogroups and penA mosaicism, facilitating multiple sequence typing from large WGS assembly collections. Exact and closest matches for existing alleles and sequence types are reported. The implementation of a fast multi-pattern searching algorithm allows pyngoST to be rapid and report results on 500 WGS assemblies in under 1 min. The mapping of typing results on a core genome tree of 2375 gonococcal genomes revealed that NG-STAR is the scheme that best represents the population structure of this pathogen, emphasizing the role of antimicrobial use and antimicrobial resistance as a driver of gonococcal evolution. This article contains data hosted by Microreact.
Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2+breast cancer
Authors: Baugh Aaron G. , Gonzalez Edgar , Narumi Valerie H. , Kreger Jesse , Liu Yingtong , Rafie Christine , Castanon Sofi , Jang Julie , Kagohara Luciane T. , Anastasiadou Dimitra P. , Leatherman James , Armstrong Todd D. , Chan Isaac , Karagiannis George S. , Jaffee Elizabeth M. , MacLean Adam , Roussos Torres Evanthia T.
Published: January 2024

Preclinical murine models in which primary tumors spontaneously metastasize to distant organs are valuable tools to study metastatic progression and novel cancer treatment combinations. Here, we characterize a novel syngeneic murine breast tumor cell line, NT2.5-lung metastasis (- LM), that provides a model of spontaneously metastatic neu-expressing breast cancer with quicker onset of widespread metastases after orthotopic mammary implantation in immune-competent NeuN mice. Within one week of orthotopic implantation of NT2.5-LM in NeuN mice, distant metastases can be observed in the lungs. Within four weeks, metastases are also observed in the bones, spleen, colon, and liver. Metastases are rapidly growing, proliferative, and responsive to HER2-directed therapy. We demonstrate altered expression of markers of epithelial-to-mesenchymal transition (EMT) and enrichment in EMT-regulating pathways, suggestive of their enhanced metastatic potential. The new NT2.5-LM model provides more rapid and spontaneous development of widespread metastases. Besides investigating mechanisms of metastatic progression, this new model may be used for the rationalized development of novel therapeutic interventions and assessment of therapeutic responses targeting distant visceral metastases

SUMMARY STATEMENT

We characterize a new syngeneic, immune-competent murine model of breast cancer (NT2.5-LM) that yields rapid and widespread metastases, preserves spontaneous metastasis, and provides a model for studying novel therapeutic interventions.
Hydrodynamic function of genal prolongations in trinucleimorph trilobites revealed by computational fluid dynamics
Authors: Pates Stephen , Drage Harriet B.
Published: January 2024

Trilobites, a diverse clade of Palaeozoic arthropods, repeatedly converged on the ‘trinucleimorph’ morphology. Trinucleimorphs possessed vaulted cephala with a broad anterior fringe and prominent posteriorly orientated genal prolongations. Various functional hypotheses have been proposed for the fringe, however the possible function of the genal prolongations has received less attention. Here we use a computational fluid dynamics approach to test whether these prolongations served a hydrodynamic function: generating negative lift to allow trinucleimorphs to remain in place on the seafloor and prevent overturning within fast flowing water. We simulated the performance of cephala with broad, narrow, and absent genal prolongations in a benthic environment with flow speeds ranging from 0.05–0.5 m s−1, in two cephalic postures. The first posture had the anterior of the cephalon parallel to the seafloor, while for the second the genal prolongations were parallel to the seafloor. Posture and presence of genal prolongations were found to be important for generating negative lift, with performance improving under faster flow speeds. No significant difference between narrow and broad genal prolongations was detected. This study provides support for genal prolongations serving a hydrodynamic function, similar to the femurs of some insect larvae, however, it does not preclude prolongations also serving additional functions as ‘snowshoes’ or antipredatory deterrents.
Medical Marijuana Had No Impact on Amphetamine Prescribing in Medicaid
Authors: Williams Errien M. , Camara Mariam , Goldhirsh Jessica L. , Piper Brian J.
Published: January 2024

Due to the uncertainty of the health effects medical marijuana poses, states differ in their medical marijuana laws (MML). Long-term effects of marijuana are found to be like attention-deficit-hyperactive disorder (ADHD). With amphetamines being prescribed to treat ADHD symptoms we hypothesized that amphetamine prescriptions would increase in states implementing MML. The number of amphetamine prescriptions filled quarterly for each state from 2006 to 2021 were calculated. States with MML and dispensaries opened before 2020 were examined and states with no MML laws were the control. Prism was utilized to visualize the data and conduct four t-tests between the pre and post of MML+ versus MML-states. Three MML+ states were excluded due to limited post-MML data. Among the remaining states, 31 were MML+ and 17 were MML-. No significant differences were found in amphetamine prescribing (p > 0.30). Medical marijuana legalization did not have a statistically significant impact on amphetamine prescribing in Medicaid patients during the analyzed period. Contrary to the hypothesis, the results revealed a non-significant decrease in prescriptions in MML+ states. Further research with recreational cannabis laws or with electronic health records is warranted.
Single-use, Metabolite Absorbing, Resonant Transducer (SMART) culture vessels for label-free, continuous cell culture progression monitoring
Authors: Chan Yee Jher , Dileep Dhananjay , Rothstein Samuel M. , Cochran Eric W. , Reuel Nigel F.
Published: January 2024

Secreted metabolites are an important class of bio-process analytical technology (PAT) targets that can correlate to cell condition. However, current strategies for measuring metabolites are limited to discrete measurements, resulting in limited understanding and ability for feedback control strategies. Herein, we demonstrated a continuous metabolite monitoring strategy using a single-use metabolite absorbing resonant transducer (SMART) to correlate with cell growth. Polyacrylate was shown to absorb secreted metabolites from living cells containing hydroxyl and alkenyl groups such as terpenoids, that act as a plasticizer. Upon softening, the polyacrylate irreversibly conformed into engineered voids above a resonant sensor, changing the local permittivity which is interrogated, contact-free, with a vector network analyzer. Compared to sensing using the intrinsic permittivity of cells, the SMART approach yields a 20-fold improvement in sensitivity. Tracking growth of many cell types such as Chinese hamster ovary, HEK293, K562, HeLa, andE. colicells as well as perturbations in cell proliferation during drug screening assays were demonstrated. The sensor was benchmarked to show continuous measurement over six days, ability to track different growth conditions, selectivity to transducing active cell growth metabolites against other components found in the media, and feasibility to scale out for high throughput campaigns.
Thermal tolerance traits of individual corals are widely distributed across the Great Barrier Reef
Authors: Denis Hugo , Bay Line K , Mocellin Véonique J.L , Naugle Melissa S , Lecellier Gaël , Purcell Steven W , Berteaux-Lecellier Véronique , Howells Emily J
Published: January 2024

Adaptation of reef-building corals to global warming depends upon standing heritable variation in tolerance traits upon which selection can act. Yet limited knowledge exists on heat tolerance variation among conspecific individuals separated by meters to hundreds of kilometers. Here, we performed standardized acute heat stress assays to quantify the thermal tolerance traits of 768 colonies ofAcropora spathulatafrom 14 reefs spanning 1060 km (9.5° latitude) of the Great Barrier Reef. Thermal thresholds for photochemical efficiency and chlorophyll retention varied considerably among individual colonies both among reefs (∼6 °C) and within reefs (∼3 °C). Although tolerance rankings of colonies varied between traits, the most heat tolerant corals (i.e. top 25% of each trait) were found at virtually all reefs, indicating widespread phenotypic variation. Reef-scale environmental predictors explained 12–62% of trait variation. Corals exposed to high thermal averages and recent thermal stress exhibited the greatest photochemical performance, likely reflecting local adaptation and stress pre-acclimatization, and the lowest chlorophyll retention suggesting stress pre- sensitization. Importantly, heat tolerance relative to local summer temperatures was the greatest on southern reefs suggestive of higher adaptive potential. These results can be used to identify naturally tolerant coral populations and individuals for conservation and restoration applications.
LHX2 regulates dendritic morphogenesis in layer II/III of the neocortex via distinct pathways in progenitors and postmitotic neurons
Authors: Bose Mahima , Ravindran Sreenath , Kumari Sanjna , Srivastava Achintya , Iyer Archana , Vedak Binita , Talwar Ishita , Narayanan Rishikesh , Tole Shubha
Published: January 2024

In the mammalian neocortex, excitatory neurons that send projections via the corpus callosum are critical to integrating information across the two brain hemispheres. The molecular mechanisms governing the development of the dendritic arbours and spines of these callosal neurons are poorly understood, yet these features are critical to their physiological properties. LIM Homeodomain 2 (Lhx2), a regulator of fundamental processes in cortical development, is expressed in postmitotic callosal neurons occupying layer II/III of the neocortex and also in their progenitors residing in the embryonic day (E) 15.5 ventricular zone of the mouse neocortex. We tested whether this factor is essential for dendritic arbour configuration and spine morphogenesis of layer II/III neurons. Here, we report loss ofLhx2,either in postmitotic layer II/III neurons or their progenitors, resulted in shrunken dendritic arbours and perturbed spine morphology. The defects were more pronounced uponLhx2disruption in progenitors, and were recapitulated when this was driven exclusively in basal progenitors. In postmitotic neurons, LHX2 regulates dendritic and spine morphogenesis via the canonical Wnt /β Catenin signalling pathway. Constitutive activation of this pathway in postmitotic neurons mimics theLhx2loss-of-function phenotype. In E15.5 progenitors, LHX2 acts in part via bHLH transcription factor NEUROG2 to regulate dendritic morphogenesis. We demonstrate that loss ofLhx2causes a massive increase inNeurog2expression, and thatNeurog2knockdown partially rescues the loss ofLhx2phenotype. Our study uncovers novel LHX2 functions consistent with its temporally dynamic and diverse roles in development.

Teaser

The mature architecture of a neuron is shaped by distinct genetic mechanisms that act in its mother cell and after it is born.
Orientation-dependent two-dimensional magnonic crystal modes in an ultralow-damping ferrimagnetic waveguide containing repositioned hexagonal lattices of
Cu
disks
Authors: Mori Kanta , Koguchi Takumi , Watanabe Toshiaki , Yoshihara Yuki , Miyashita Hibiki , Grundler Dirk , Inoue Mitsuteru , Ishiyama Kazushi , Goto Taichi
Published: January 2024

Two-dimensional (2D) hexagonal lattices of Cu disks are shown to induce orientation-dependent magnonic crystal (MC) modes for propagating forward volume spin waves in a single-crystal yttrium iron garnet (YIG) film. The width and depth of the magnonic band gaps are 0.022 GHz and –15.2 dB at the frequency of 1.815 GHz. Integrating differently oriented lattices on the same YIG film and positioning them between the microwave antenna surrounded by magnon absorbers consisting of Au films, we clearly resolve a characteristic frequency shift of the magnonic band gap by altering the incident angle of the spin waves to the 2D MC. The shift amounts to approximately 10 MHz when the incident angle is changed between 10° and 30°. The obtained results show a good agreement with calculations using the finite integration technique and are a step toward complete band-gap investigations in YIG of ultralow spin-wave damping.

Published by the American Physical Society
2024
Decoding 122-type iron-based superconductors: A comprehensive simulation of phase diagrams and transition temperatures
Authors: Wong Chi Ho , Lortz Rolf
Published: January 2024

Iron-based superconductors, a cornerstone of low-temperature physics, have been the subject of numerous theoretical models aimed at deciphering their complex behavior. In this study, we present a comprehensive approach that amalgamates several existing models and incorporates experimental data to simulate the superconducting phase diagrams of the principal “122-type” iron-based compounds. Our model considers a multitude of factors including the momentum dependence of the superconducting gap, spin-orbital coupling, antiferromagnetism, spin-density wave, induced XY potential on the tetrahedral structure, and electron-phonon coupling. We have refined the electron-phonon scattering matrix using experimental angle-resolved photoemission spectroscopy data, ensuring that relevant electrons pertinent to iron-based superconductivity are accounted for. This innovative approach allows us to calculate theoretical critical temperature (Tc) values for Ba1−xKxFe2As2, CaFe2As2, and SrFe2As2 as functions of pressure. These calculated values exhibit remarkable agreement with experimental findings. Furthermore, our model predicts that MgFe2As2 remains nonsuperconducting irrespective of the applied pressure. Given that 122-type superconductivity at low pressure or low doping concentration has been experimentally validated, our work serves as a powerful predictive tool for generating superconducting phase diagrams at high pressure empirically. This study underscores that the high transition temperatures and the precise doping and pressure dependence of iron-based superconductors are intrinsically linked to an intertwined mechanism involving a strong interplay between structural, magnetic, and electronic degrees of freedom.

Published by the American Physical Society
2024
Ultrafast shift current dynamics in
WS2
monolayer
Authors: He Fuxiang , Chen Daqiang , Ren Xinguo , Meng Sheng , He Lixin
Published: January 2024

The shift current effect, in materials lacking inversion symmetry, may potentially allow the performance of photovoltaics to surpass the Shockley-Queisser limit for traditional p−n junction-based photovoltaics. Although the shift-current effect has been studied from first principles via second-order perturbation theory, an understanding of the dynamics of hot carriers is still lacking. We investigate the dynamics of the shift current in monolayer WS2 via real-time propagation time-dependent density functional theory (rt-TDDFT). We find that the shift current can be generated within 10–20 fs after turning on the lights, and dissipates within approximately a few tens of femtoseconds after turning off the lights. This property can be used for ultrafast photon detection. This work provides an important step toward understanding the dynamics of shift-current effects, which is crucial for device applications.

Published by the American Physical Society
2024
The role of intellectual and social capital in funding businesses: a cross-country analysis
Authors: Mongrut Samuel , Berggrun Luis , Cortez Alejandro Klender , Rodríguez García Martha del Pilar
Published: January 2024

Purpose

The study aims to examine the impact of intellectual and social capital in funding businesses.

Design/methodology/approach

The study made use of fixed-effects panel data models with a sample of 142 countries from the five continents during the period 1998–2018.

Findings

It was found that human capital (HC), relational capital, structural capital and social capital play a role in investors’ decisions to fund a business. The study revealed that investors’ funding decisions in low human development index countries are based mainly on education, while those in high human development index countries are based mainly on the creativity component of HC and on relational, structural and social capital.

Research limitations/implications

The study needs to be replicated using firm-level data within each country. Moreover, the search for new proxies for intellectual and social capital (although the list of variables is exhaustive) both at the country and firm level, constitutes an interesting avenue for future research.

Practical implications

Countries should pay attention to intellectual and social capital to encourage business activity. In particular, low human development countries should strengthen HC, such as the school enrollment rate, with early entrepreneurial training and increase research and development investments, while high human development countries should continue to foster strategic alliances, protect intellectual property and maintain or increase the level of trust in the country.

Originality/value

The study contributes to literature by being the first to explore such a variety of intellectual and social capital variables from a country-level perspective.
Racelighting Black, Indigenous and People of Color in education: a conceptual framework
Authors: Wood J. Luke , Harris III Frank
Published: January 2024

Purpose

This article provides an overviews of the concept of racelighting. Racelighting is “is an act of psychological manipulation where Black, Indigenous, and People of Color (BIPOC) receive racial messages that lead them to second-guess their lived experiences with racism”

Design/methodology/approach

This conceptual paper articulates four primary ways that racelighting manifests in the lives and experiences of Black, Indigenous and People of Color (BIPOC).

Findings

There are four common messages that often lead to racelighting: stereotype advancement, resistive actions, inauthentic allyship and misrepresenting the past.

Originality/value

While much has been written about gaslighting, few frameworks articulate how gaslighting occurs in a racialized context.
Developing entrepreneurial resilience from uncertainty as usual: a learning theory approach on readiness, response and opportunity
Authors: Kromidha Endrit , Bachtiar Nia Kurniati
Published: January 2024

Purpose

This study explores resilience learning from uncertainty, taking a holistic view by considering individual, firm and contextual factors. Resilience development is understood by focusing on how uncertainty is related to entrepreneurs and their environment, suggesting that developing resilience needs to be a continuous learning process.

Design/methodology/approach

This qualitative study explores factors related to entrepreneurial uncertainty, resilience and learning. Evidence is drawn from interviews with rural entrepreneurs in two regions of Indonesia, and analyzed using a rigorous approach to generate codes, second-order themes and aggregate dimensions for the theoretical contributions.

Findings

Uncertainty readiness, uncertainty response and uncertainty opportunity for resilience emerge as the key learning areas from this study. They are related to resilience on a personal, community and systemic level. The proposed framework relates learning from uncertainty to the process of developing resilience for entrepreneurs and their communities.

Originality/value

This study proposes a framework based on resilience motivation and learning from uncertainty as usual. It explores the relationships between uncertainty readiness, responses and opportunities with personal, relational and systemic resilience factors. This contributes to entrepreneurship behavior research at the intersection of organization studies and management in the socio-economic and often informal context of developing countries.
From business incubator to crucible: a new perspective on entrepreneurial support
Authors: Valliere Dave , Nicholls-Nixon Charlene L.
Published: January 2024

Purpose

Although business incubators are a widely recognized form of entrepreneurial support, this paper aims to challenge the assumption that incubation is necessarily beneficial for early-stage entrepreneurs, and considers cases where, due to variability in the motives and behaviours of entrepreneurs, incubation may be unwarranted or even undesireable.

Design/methodology/approach

This study presents a theoretically derived typology of incubated entrepreneurs, based on their entrepreneurial competence and capacity for learning, which asserts that incubation may be unwarranted or even undesireable for three of the four proposed entrepreneur types. Qualitative data from interviews with entrepreneurs and managing directors from 10 business incubators is used to illustrate the existence of these types.

Findings

The data provides evidence of entrepreneurial types whose incubation may be counterproductive to the goals and objectives of their host incubators.

Practical implications

Implications for incubator management (intake screening and ongoing monitoring of portfolio) are developed and aimed at improving the outcomes of business incubation for stakeholders.

Originality/value

The paper contributes to the incubation typology literature by challenging a widely held assumption that entrepreneurs have the potential to benefit from incubation and by reconceptualizing incubators as “crucibles” that perform a critical function in distinguishing high-potential entrepreneurs.
Trans-functional green wall’s developed predesign model as a first stage to designers to understand the design and potential performance aspects of green walls
Authors: Refaat Tamer , El-Zoklah Marwa
Published: January 2024

Purpose

This study aims to formulate a user-friendly pre-design model that could be a decision support tool for green wall systems to assist designers in selecting an optimal green wall system aligned with specified performance criteria while concurrently addressing project requirements linked to social and economic parameters. This approach seeks to enhance overall project satisfaction for the designer and the owner.

Design/methodology/approach

A correlation between the green wall context and design requirements and its performance on the buildings have been defined by considering its social and economic parameters, which represented the owner preferences to ensure the most satisfaction from installation as it achieves the required performance that is defined by the designer such as maximizing thermal insulation, improving indoor air quality, reducing the needed heating and cooling loads, etc. and also to achieve the satisfaction in social and economic requirements defined by the owner such as system installation cost, system maintenance cost, adding beauty value, etc.

Findings

The research developed an easy pre-design model to be a tool for green wall system decision-making for the most suitable system, which contains three main steps: the first one is defining the required performance of the green wall (designer requirements), the second step is limiting the context of the project which is made by designer and the owner requirements and finally the third step is choosing the system components that ensures achieving the requirements of both owners and designer, related to the building and climate context.

Originality/value

The added value lies in developing a green wall decision-making tool, essentially a pre-design model. This model considers the correlation between the project’s context, encompassing climate and building conditions. It provides a structured approach for decision-making in the early stages of green wall design. It offers valuable insights into the optimal choices related to system type, installation methods and plant characteristics. This enhanced decision-making tool contributes to more informed and efficient design processes, considering each project’s specific needs and conditions.
Effect of isobornyl acrylate and hexanediol diacrylate on the properties of UV-curable resin developed from suberic acid-derived polyester polyol
Authors: Mahajan Umesh , Mhaske S.T.
Published: January 2024

Purpose

This study aims to focus on how reactive diluents with mono- and di-functionalities affect the properties of resin formulation developed from bioderived precursors. A hydroxyethyl methacrylate (HEMA) terminated urethane acrylate oligomer was synthesized and characterized to study its application in stereolithography 3D printing with different ratios of isobornyl acrylate and hexanediol diacrylate.

Design/methodology/approach

Polyester polyol was synthesized from suberic acid and butanediol. Additionally, isophorone diisocyanate, polyester polyol and HEMA were used to create urethane acrylate oligomer. Fourier transform infrared spectroscopy and 1H NMR were used to characterize the polyester polyol and oligomer. Various formulations were created by combining oligomer with reactive diluents in concentrations ranging from 0% to 30% by weight and curing with ultraviolet (UV) radiation. The cured coatings and 3D printed specimens were then evaluated for their properties.

Findings

The findings revealed an improvement in thermal stability, contact angle value, tensile strength and surface properties of the product which indicated its suitability for use as a 3D printing material.

Originality/value

This study discusses how oligomers that have been cured by UV radiation with mono- and difunctional reactive diluents give excellent coating characteristics and demonstrate suitability and stability for 3D printing applications.
Environmental corporate social responsibility initiatives and green customer citizenship behavior in tourism industry: the mediating roles of green trust, customer-company identification and green corporate image
Authors: Waris Idrees , Suki Norazah Mohd , Ahmed Adeel , Barkat Waseem
Published: January 2024

Purpose

Environmental issues have triggered the need for sustainable behavior around the globe. The tourism industry’s rapid growth also contributes to environmental degradation through natural resource depletion and excess water and energy utilization. Based on social identity theory, this study aims to assess the impact of environmental corporate social responsibility initiatives on green customers’ citizenship behavior. Furthermore, the study assesses the mediating effects of green trust, customer–company identification and green image.

Design/methodology/approach

This study is a quantitative approach, and purposive sampling technique was used to collect the data from the hotels’ customers from northern areas of Pakistan. This study used partial least square-structural equation modeling to analyze the data of 426 customers.

Findings

The study’s findings show that environmental corporate social responsibility initiatives significantly impact green customers’ citizenship behavior, green trust, customer–company identification and green corporate image. However, the relationship between green corporate image and green customers’ citizenship behavior was insignificant. Furthermore, the study’s results revealed that green trust and customer–company identification partially mediate between environmental corporate social responsibility initiatives and green customers’ citizenship behavior.

Practical implications

The findings suggest that hotels’ environmental corporate social responsibility initiatives improve green customer citizenship behavior, green trust and enhance customer–company identification. Therefore, hotel industry managers should consider reinforcing existing environmental corporate social responsibility initiatives and make further efforts to highlight the importance of such initiatives for environmental sustainability, which ultimately affects customers’ green customer citizenship behavior.

Originality/value

This research developed a novel framework to understand green customers’ citizenship behavior in the tourism industry. It extended the literature on environmental corporate social responsibility initiatives and green customers’ citizenship behavior. In addition, the research adds value by confirming the significant direct and mediating role of customer–company identification in tourism industry context.
Improvement of SAC0307/Cu column friction plunge micro-welding quality by static constraint
Authors: Li Zhenkun , Zhao Zhili , Liu Jinliang , Ding Xin
Published: January 2024

Purpose

To solve the problems caused by using precise molds for copper column positioning in the current column grid array package, this paper aims to optimize the proposed friction plunge micro-welding (FPMW) technology without mold assistance, to overcome the problems of low interfacial bonding strength, shrinkage cavities and flash defects caused by the low hold-tight force of solder on the copper column.

Design/methodology/approach

A pressurizing device installed under the drill chuck of the friction welding machine is designed, which is used to apply a static constraint to the solder ball obliquely downward to increase the hold-tight force of the peripheral solder on the copper column during welding and promote the friction metallurgical connection between them.

Findings

The results show that the application of static constraint during welding can increase the compactness of the solder near the friction interface and effectively inhibit occurrences of flash, shrinkage cavities and crystal defects such as vacancies. Therefore, compared with the unconstrained (UC) FPMW, the average strength of the statically constrained (SC) FPMW joints and aged SC-FPMW joints can be increased by 51.1% and 122.6%, and the problem of the excessive growth of the interfacial connection layer in the UC-FPMW joints during aging can be effectively avoided.

Originality/value

The application of static constraint effectively inhibits the occurrence of defects such as shrinkage cavities, vacancies and flash in FPMW joints, and the welding quality is significantly improved.
Moderating role of government effectiveness and innovation in sustainable economic growth relationship in Middle East & North Africa countries
Authors: Saleem Sardar Fawad , Khan Muhammad Azam , Tariq Muhammad
Published: January 2024

This article examines the impact of government effectiveness (GE) and technological innovation on economic growth and environmental degradation in Middle East & North Africa countries. The study utilizes panel data from the period of 2002–2020. The findings indicate that there is a significant and positive relationship between innovation (INV) and CO2 emissions (0.0244), while GE has a significant and negative impact on CO2 emissions (−0.5753). In a similar vein, it can be observed that both INV and government efficacy exert a substantial and favorable influence on the process of economic growth (0.0353 and 0.0773). Furthermore, the interaction of INV and GE showed a noteworthy moderating effect on CO2 emissions (−0.1581). Conversely, it exhibited a more pronounced positive influence on economic growth (0.1122). The study highlights that synergizing INV with GE is essential for attaining sustainable economic growth in the studied area.
A study of DNA transfers onto plastic packets placed in personal bags
Authors: Lee Li Yen Candy , Lee Yong Sheng , Tan Jiayu , Lee Jun Yu , Syn Christopher Kiu‐Choong
Published: January 2024

The ability to detect low level DNA brings with it the uncertainty of whether the detected DNA is a result of transfer. To address this uncertainty, a simulation study was conducted in which a mock illicit drug packet was placed into the personal bags of individuals. When the average transit time of the packets was increased from around 2 h to more than 14 h, the percentage of the DNA profiles recovered from the packets which could be attributed to the individuals increased greatly from 5.3% to 48.6%. We found that drug packers who were poor shedders could not be included as contributors to the DNA profiles from the drug packets at all and there was a higher chance that individuals other than themselves could be included as contributors to the DNA profile recovered from drug packets. We also found that it was equally likely that the drug packers who had direct contact with the drug packets and bag owners who did not, could be included as contributors to the DNA profiles recovered from the packets. The results in this study highlight the importance of taking into consideration the transit time of drug packet, the shedder status of the alleged packer and the history of an item, when evaluating DNA evidence in the context of illicit drug activities.
Aligned or non‐aligned: South Africa's response to the war in Ukraine
Authors: Brosig Malte
Published: January 2024

This contribution explores South Africa's position in the war in Ukraine. As a major African player, member of BRICS, the G20, and frequent UN Security Council member, the country is a globally engaged and regionally leading actor. Since the beginning of the conflict, South Africa has declared itself as non‐aligned; however, its close political relations with Russia and disinclination to condemn the invasion have raised the issue of whether the country is only declaratory neutral. Although South Africa is only indirectly affected by the war, it was chiefly involved in the first major peace initiative spearheaded by a select group of African countries. This contribution traces South Africa's official state response to the war, exploring its narrative of the conflict and is interrogating its version of non‐alignment in the context of a transitioning world order.
Explaining the source of racial disparities in market facilitation program payments
Authors: Hendricks Nathan P. , Murphy Ashling M. , Morgan Stephen N. , Padilla Samantha L. , Key Nigel
Published: January 2024

This paper provides new insights on the distribution of agricultural government payments by farm operator race and the sources of disparities. We use farm‐level data from the Census of Agriculture to estimate the payments each farm was eligible to receive from the 2018 and 2019 Market Facilitation Program. We find that farms with a White operator were eligible to receive significantly more payments than farms with a non‐White operator. Most of the disparity for farms with a Black operator is due to differences in average farm size, because there are few large farms with a Black operator. The disparities for farms with an American Indian, Asian, or Pacific Islander operator were roughly half due to farm size and half due to the location of these farms and the types of commodities they tend to produce.
The people think what I think: False consensus and unelected elite misperception of public opinion
Authors: Furnas Alexander C. , LaPira Timothy M.
Published: January 2024

Political elites must know and rely faithfully on the public will to be democratically responsive. Recent work on elite perceptions of public opinion shows that reelection‐motivated politicians systematically misperceive the opinions of their constituents to be more conservative than they are. We extend this work to a larger and broader set of unelected political elites such as lobbyists, civil servants, journalists, and the like, and report alternative empirical findings. These unelected elites hold similarly inaccurate perceptions about public opinion, though not in a single ideological direction. We find this elite population exhibits egocentrism bias, rather than partisan confirmation bias, as their perceptions about others' opinions systematically correspond to their own policy preferences. Thus, we document a remarkably consistent false consensus effect among unelected political elites, which holds across subsamples by party, occupation, professional relevance of party affiliation, and trust in party‐aligned information sources.
The association between ambient temperature and semen quality in a Northern Peninsular Province, China
Authors: Wang Li , Qu Yinan , Han Wenkai , Cai Meng , Ma Wei , Zhao Qi , Chen Zi‐Jiang
Published: January 2024

Background

Extreme ambient temperature has been linked to decline in males’ semen quality. Although the temperature–semen quality association has been examined in certain cities of South China, how the effect size of the extreme temperature may lag over critical windows in spermatogenesis and whether the strength of association may vary in North China have yet been adequately explored.

Objectives

To quantify the association between air temperature and semen quality, and identify critical exposure windows in a Northern Peninsular Province, China.

Materials and methods

Data on semen quality in 2014−2019 were collected from the Human Sperm Bank of Institute of Women, Children and Reproductive Health, Shandong University, China. Daily meteorological data (0.01°×0.01°) were assigned to each subject's residential address. The linear mixed‐effect model combined with the distributed lag nonlinear model was used to estimate the effect of ambient temperature over critical spermatogenesis windows.

Results

The temperature–semen quality association was inverted V‐shaped, with the maximum lag being 0–45 days before ejaculation and the threshold being 9.2°C. Progressively and total motile sperm number, and total sperm number declined more substantially than other semen quality parameters. Semen quality was more sensitive to cold exposure during the epididymal storage period than the sperm motility development period. By contrast, semen quality was insensitive to heat exposure during both critical spermatogenesis windows. Impairment of certain semen quality parameters was more obvious for males with higher educational attainment and those aged over 35 years.

Discussion and conclusion

Exposure to non‐optimal temperature is associated with decreased semen quality in North China, with the epididymal storage and sperm motility development periods more sensitive to cold exposure than heat. Older males and those with higher educations may need particular awareness.