bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemical Vapor Transport of Solid Solutions. Part 13. The Chemical Vapor Transport of Mixed Crystals in the System ZnS/Zn3P2.
Authors: Locmelis S. , Binnewies M.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Chemical Vapor Transport of Solid Solutions. Part 14. Chemical Vapor Transport of GaP and of Mixed Crystals in the System ZnS/GaP.
Authors: Locmelis S. , Binnewies M.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Combinatorial Investigations of the Si—Al—Mn System for Li‐Ion Battery Applications.
Authors: Fleischauer M. D. , Dahn J. R.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Syntheses and Characterization of Some Mixed Te/Se Polychalcogenide Anions [TemSen]2‐.
Authors: Sekar Perumal , Ibers James A.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Tetramethylammonium Pentaborate 0.25‐Hydrate.
Authors: Zhang Hong‐Xia , Zheng Shou‐Tian , Yang Guo‐Yu
Published: September 2004

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Synthesis, Structure, and Properties of New Perovskite PbVO3.
Authors: Shpanchenko Roman V. , et al. et al.
Published: September 2004

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A New Iron Oxyhydroxide Phase: The Molybdate‐Substituted Analogue of Akaganeite.
Authors: Richmond William R. , Hockridge James G. , Loan Mitch , Parkinson Gordon M.
Published: September 2004

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Enantioselective Alkynylation of Aldehydes Catalyzed by [2.2]Paracyclophane‐Based Ligands.
Authors: Dahmen Stefan
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Role of Noncovalent Interactions in the Enantioselective Reduction of Aromatic Ketimines with Trichlorosilane.
Authors: Malkov Andrei V. , Mariani Andrea , MacDougall Kenneth N. , Kocovsky Pavel
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Phase‐Transfer‐Catalyzed Asymmetric Glycolate Alkylation.
Authors: Andrus Merritt B. , Hicken Erik J. , Stephens Jeffrey C.
Published: September 2004

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Exo‐ and Endocyclic Oxazolinyl—Phosphane Palladium Complexes: Catalytic Behavior in Allylic Alkylation Processes.
Authors: Franco Delphine , Gomez Montserrat , Jimenez Francisco , Muller Guillermo , Rocamora Merce , Maestro Miguel Angel , Mahia Jose
Published: September 2004

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Palladium‐Catalyzed Conversion of β,γ‐Unsaturated Silyl Sulfinates into (E)‐Alkenes: Asymmetric Synthesis of Polypropionate Fragments.
Authors: Huang Xiaogen , Craita Cotinica , Vogel Pierre
Published: September 2004

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Synthesis of a Renewable Hydroperoxide from (+)‐Norcamphor: Influence of Steric Modifications of the Bicyclic Framework on Asymmetric Sulfoxidation.
Authors: Lattanzi Alessandra , Iannece Patrizia , Scettri Arrigo
Published: September 2004

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Highly Efficient and Enantioselective Cyclization of Aromatic Imines via Directed C—H Bond Activation.
Authors: Thalji Reema K. , Ellman Jonathan A. , Bergman Robert G.
Published: September 2004

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Enantioselective Allylation of Alkyl Glyoxylates Catalyzed by (Salen)chromium(III) Complexes.
Authors: Kwiatkowski Piotr , Chaladaj Wojciech , Jurczak Janusz
Published: September 2004

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Palladium‐Catalyzed Enantioselective Allylic Alkylation of Thiocarboxylated Ions: Asymmetric Synthesis of Allylic Thioesters and Memory Effect/Dynamic Kinetic Resolution of Allylic Esters.
Authors: Luessem Bernhard J. , Gais Hans‐Joachim
Published: September 2004

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Asymmetric Reduction of Enones with Synechococcus sp. PCC 7942.
Authors: Shimoda Kei , Kubota Naoji , Hamada Hiroki , Kaji Misato , Hirata Toshifumi
Published: September 2004

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Ruthenium/Chloride Catalytic System for Conjugate Addition of Terminal Alkynes to Acrylate Esters.
Authors: Nishimura Takahiro , Washitake Yosuke , Nishiguchi Yoshiki , Maeda Yasunari , Uemura Sakae
Published: September 2004

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Dithiocarbamate Group Transfer Cyclization Reactions of Carbamoyl Radicals under “Tin‐Free” Conditions.
Authors: Grainger Richard S. , Innocenti Paolo
Published: September 2004

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Solid Supported Microwave‐Assisted Beckmann Rearrangement of Ketoximes in Dry Media.
Authors: Moghaddam Firouz Matloubi , Rad Abbas Ali Rastegar , Zali‐Boinee Hassan
Published: September 2004

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A Novel Tin‐Free Procedure for Alkyl Radical Reactions.
Authors: Benati Luisa , Leardini Rino , Minozzi Matteo , Nanni Daniele , Scialpi Rosanna , Spagnolo Piero , Strazzari Samantha , Zanardi Giuseppe
Published: September 2004

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Oxidation of Thiols with 1‐Butyl‐4‐aza‐1‐azoniabicyclo[2.2.2]octane Dichromate (BABOD) under Non‐Aqueous Conditions.
Authors: Hajipour A. R. , Bagheri Hamid , Ruoho Arnold E.
Published: September 2004

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Aerobic Oxidation of Thiols to Disulfides Catalyzed by Trichlorooxyvanadium.
Authors: Kirihara Masayuki , Okubo Kumiko , Uchiyama Tomoyuki , Kato Yoko , Ochiai Yuta , Matsushita Shinya , Hatano Akihiko , Kanamori Kan
Published: September 2004

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Palladium Catalyzed Amination of Vinyl Chlorides: A New Entry to Imines, Enamines and 2‐Amino‐1,3‐butadienes.
Authors: Barluenga Jose , Fernandez M. Alejandro , Aznar Fernando , Valdes Carlos
Published: September 2004

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Potassium Hexacyanoferrate(II) — A New Cyanating Agent for the Palladium‐Catalyzed Cyanation of Aryl Halides.
Authors: Schareina Thomas , Zapf Alexander , Beller Matthias
Published: September 2004

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Nickel‐Catalyzed Cross‐Coupling of Organosilicon Reagents with Unactivated Secondary Alkyl Bromides.
Authors: Powell David A. , Fu Gregory C.
Published: September 2004

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Activation by Allylic Alcohols of Sulfur‐Containing Dienes to Ruthenium‐Catalyzed Ring‐Closing Metathesis.
Authors: Rowlands Gareth J. , Singleton John
Published: September 2004

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Bis(diazaphospholidine) Ligands for Asymmetric Hydroformylation: Use of ESPHOS and Derivatives Based on Ferrocene and Diarylether Backbones.
Authors: Clarkson Guy J. , Ansell Jeffrey R. , Cole‐Hamilton David J. , Pogorzelec Peter J. , Whittell John , Wills Martin
Published: September 2004

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An Improved Greener Esterification of Fatty Alcohols Using a Renewable Acid—Ionic Liquid Couple as Catalyst—Solvent.
Authors: Nguyen Hoang‐Phuong , Znifeche Samira , Baboulene Michel
Published: September 2004

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Stereoselective Preparation of Deuteriated Dienes by Ring Fragmentation of Metalated Cyclopropylcarbinols.
Authors: Zohar Elinor , Ram Mirit , Marek Ilan
Published: September 2004

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Mild and Facile Procedure for Clay‐Catalyzed Acetonide Protection and Deprotection of N(Boc)‐Amino Alcohols and Protection of 1,2‐Diols.
Authors: Shaikh Nadim S. , Bhor Santosh S. , Gajare Anil S. , Deshpande Vishnu H. , Wakharkar Radhika D.
Published: September 2004

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Transition‐Metal‐Based Lewis Acid Catalysis of Aza‐Type Michael Additions of Amines to α,β‐Unsaturated Electrophiles in Water.
Authors: Xu Li‐Wen , Li Lyi , Xia Chun‐Gu
Published: September 2004

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Chemistry of Diazocarbonyl Compounds. Part 18. Synthesis and Spectral Parameters of 1,3‐Dialkyl‐3‐hydroxy‐2‐diazoketones.
Authors: Zhdanova O. V. , Korneev S. M. , Nikolaev V. A.
Published: September 2004

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Highly Selective Isomerization of Allyloxyalcohols to Cyclic Acetals or 1‐Propenyloxyalcohols.
Authors: Urbala Magdalena , Kuznik Nikodem , Krompiec Stanislaw , Rzepa Jozef
Published: September 2004

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Functional Methacryloyloxy Acetals. Part 5. Electrophilic Addition of Carboxylic Acids to 2‐Vinyloxyethyl Methacrylate.
Authors: Vysotskaya O. V. , Oparina L. A. , Parshina L. N. , Tatarinova A. A. , Trofimov B. A.
Published: September 2004

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A Straightforward and Mild Synthesis of Functionalized 3‐Alkynoates.
Authors: Suarez Andres , Fu Gregory C.
Published: September 2004

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Domino Carbocationic Rearrangements of α‐[Bis(methylthio)methylene]alkyl‐2‐(heteroaryl)cyclopropyl Ketones.
Authors: Peruncheralathan S. , Sriram V. , Ila H. , Junjappa H.
Published: September 2004

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Synthesis of 2‐Substituted Cyclobutanones as γ‐Irradiation Marker Products of Lipid‐Containing Foods.
Authors: Verniest Guido , Boterberg Stefaan , Colpaert Jeroen , Van Thienen Tinneke , Stevens Christian V. , De Kimpe Norbert
Published: September 2004

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Silver‐Catalyzed [2 + 2] Cycloadditions of Siloxy Alkynes.
Authors: Sweis Randy F. , Schramm Michael P. , Kozmin Sergey A.
Published: September 2004

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Insertion of (E)‐(1,2‐Dihalovinyl)lithium and (2‐Haloethynyl)lithium into Zirconacycles.
Authors: Norton David , Whitby Richard J. , Griffen Ed
Published: September 2004

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Hexafluoroisopropanol: A Powerful Solvent for the Hydrogenation of Functionalized Aromatic Compounds.
Authors: Fache Fabienne , Piva Olivier
Published: September 2004

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Palladium‐Tetraphosphine Complex: An Efficient Catalyst for the Alkynylation of ortho‐Substituted Aryl Bromides.
Authors: Feuerstein Marie , Berthiol Florian , Doucet Henri , Santelli Maurice
Published: September 2004

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Lewis Acid Promoted Aldol Reaction of Fluorinated Silyl Enol Ethers from New Fluoroacetylsilane Derivatives.
Authors: Chung Woo Jin , Ngo Silvana C. , Higashiya Seiichiro , Welch John T.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Selective Reduction of Azoarenes into Arylamine(s) by Aluminum/NH4Br under Sonic Conditions.
Authors: Pasha M. A. , Jayashankara V. P.
Published: September 2004

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Detritylation of N‐Tritylamines via a Naphthalene‐Catalyzed Lithiation Process.
Authors: Behloul Cherif , Guijarro David , Yus Miguel
Published: September 2004

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An Efficient One‐Pot Synthesis of Phenol Derivatives by Ring Opening and Rearrangement of Diels—Alder Cycloadducts of Substituted Furans Using Heterogeneous Catalysis and Microwave Irradiation.
Authors: Moreno Andres , Gomez Maria Victoria , Vazquez Ester , de la Hoz Antonio , Diaz‐Ortiz Angel , Prieto Pilar , Mayoral Jose Antonio , Pires Elisabet
Published: September 2004

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Photoinduced Oxidative Dehydrogenation of Benzylic Alcohols Using Mercury(II) Oxide.
Authors: Habibi M. H. , Farhadi S.
Published: September 2004

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Reduction of 1,2‐Dicarbonyl Compounds Mediated by the Combination of Phosphine and Lewis Acid.
Authors: Kikuchi Satoshi , Hashimoto Yukihiko
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Rh(I)‐Catalyzed Solvent‐Free ortho‐Alkylation of Aromatic Imines under Microwave Irradiation.
Authors: Vo‐Thanh Giang , Lahrache Hind , Loupy Andre , Kim In‐Jung , Chang Duck‐Ho , Jun Chul‐Ho
Published: September 2004

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A Highly Efficient and Practical New PEG‐Bound Bi‐Cinchona Alkaloid Ligand for the Catalytic Asymmetric Aminohydroxylation of Alkenes.
Authors: Yang Xi‐Wen , Liu Han‐Quan , Xu Ming‐Hua , Lin Guo‐Qiang
Published: September 2004

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Synthesis of N‐Acylarenesulfonamides.
Authors: Utkina E. N. , Michurin A. A. , Shishulina A. V.
Published: September 2004

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CuI‐Catalyzed Coupling Reactions of Aryl Iodides and Bromides with Thiols Promoted by Amino Acid Ligands.
Authors: Deng Wei , Zou Yan , Wang Ye‐Feng , Liu Lei , Guo Qing‐Xiang
Published: September 2004

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Organic Reactions in Ionic Liquids: An Efficient Method for the Synthesis of Aryl Sulfones by Alkylation of Sodium Arenesulfinates with Alkyl Halides.
Authors: Hu Yi , Chen Zhen‐Chu , Le Zhang‐Gao , Zheng Qin‐Guo
Published: September 2004

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Niobium‐Catalyzed Reduction of Monofluoroarenes with LiAlH4.
Authors: Fuchibe Kohei , Akiyama Takahiko
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Simple Amine/Pd(OAc)2‐Catalyzed Suzuki Coupling Reactions of Aryl Bromides under Mild Aerobic Conditions.
Authors: Tao Bin , Boykin David W.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Metal Bis{(trifluoromethyl)sulfonyl}amide Complexes: Highly Efficient Friedel—Crafts Acylation Catalysts.
Authors: Earle Martyn J. , Hakala Ullastiina , McAuley Barry J. , Nieuwenhuyzen Mark , Ramani Alwar , Seddon Kenneth R.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
The Heck Coupling Reaction Using Aryl Vinyl Ketones: Synthesis of Flavonoids.
Authors: Bianco Armandodoriano , Cavarischia Claudia , Guiso Marcella
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Recyclable Sonogashira Coupling Reactions in an Ionic Liquid, Effected in the Absence of Both a Copper Salt and a Phosphine.
Authors: Park Soon Bong , Alper Howard
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Synthesis of 1,6‐Disubstituted Spiro[4,4]nonanes by Palladium Mediated Transmetallation Reactions.
Authors: Sirbu Doina
Published: September 2004

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Promotion of One‐Pot Robinson Anellation Achieved by Gradual Pressure and Temperature Manipulation under Supercritical Conditions.
Authors: Kawanami Hajime , Ikushima Yutaka
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Stereoselectivity in the Intermolecular Pauson—Khand Reaction of Electron‐Deficient Terminal Alkynes.
Authors: Sola Jordi , Riera Antoni , Pericas Miquel A. , Verdaguer Xavier , Maestro Miguel A.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
New Phenylselanyl Group Activation: Synthesis of Aziridines and Oxazolidin‐2‐ones.
Authors: Miniejew Catherine , Outurquin Francis , Pannecoucke Xavier
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
A Convenient Preparation of Tetrahydrofuran‐Based Diamines.
Authors: Lai Gaifa
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Facile One‐Pot Synthesis of Di‐ and Tri‐Substituted Furans from Acyl Isocyanates Using Trimethylsilyldiazomethane.
Authors: Hari Yoshiyuki , Iguchi Tomoe , Aoyama Toyohiko
Published: September 2004

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Synthesis of Benzo[b]naphtho[2,3‐d]furan‐6,11‐dione via One‐Pot Remote Anionic Fries Rearrangement and Metalation Reaction.
Authors: Azevedo Mariangela S. , Alves Glaucia B. C. , Cardoso Jari N. , Lopes Rosangela S. C. , Lopes Claudio C.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Highly Enantioselective Synthesis of Chiral 3‐Substituted Indolines by Catalytic Asymmetric Hydrogenation of Indoles.
Authors: Kuwano Ryoichi , Kaneda Kohei , Ito Takashi , Sato Koji , Kurokawa Takashi , Ito Yoshihiko
Published: September 2004

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Synthesis of Substituted Carbazoles and β‐Carbolines by Cyclization of Diketoindole Derivatives.
Authors: Duval Eric , Cuny Gregory D.
Published: September 2004

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Synthesis of 2,3′‐Diindolylmethanes and Substituted Indolo[3,2‐b]carbazoles.
Authors: Wahlstroem Niklas , Stensland Birgitta , Bergman Jan
Published: September 2004

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Functional Room‐Temperature Ionic Liquids as Lubricants for an Aluminum‐on‐Steel System.
Authors: Mu Zonggang , Liu Weimin , Zhang Shuxiang , Zhou Feng
Published: September 2004

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Synthesis of Imidazolo[5,4‐b]carbazole‐4,10‐quinones.
Authors: Desforges Gwenaelle , Bossert Cecile , Montagne Cyril , Joseph Benoit
Published: September 2004

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One‐Pot Synthesis of Phenytoin Analogues.
Authors: Mahmoodi N. O. , Emadi S.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Thiourea Inhibitors of Herpes Viruses. Part 2. N‐Benzyl‐N′‐arylthiourea Inhibitors of CMV.
Authors: Bloom Jonathan D. , et al. et al.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Structure—Activity Relationships of 2‐Aminothiazole Derivatives as Inducible Nitric Oxide Synthase Inhibitor.
Authors: Ueda Shigeo , Terauchi Hideo , Kawasaki Motoji , Yano Akihiro , Ido Motoharu
Published: September 2004

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A New Method of Synthesis of Triazolobenzimidazole.
Authors: Zniber Rachid , Moussaif Ahmed , Achour Redouane , El Ghoul Mostafa , Hakam Asmae , Souhassou Mohamed
Published: September 2004

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Synthesis and Biological Activity of Some Isoniazid Based 1,3,4‐Oxadiazole Derivatives.
Authors: Khan M. S. Y. , Chawla Gita , Mueed M. Asad
Published: September 2004

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Synthesis of 4,5‐Dihydro‐1,3,4‐thiadiazole‐2‐carboxamide and 2‐Carbamoyl‐4,5‐dihydro‐1,3,4‐thiadiazole 1‐Oxide Derivatives Based on Hydrazones of Oxamic Acid Thiohydrazides.
Authors: Yarovenko V. N. , Shirokov A. V. , Zavarzin I. V. , Krupinova O. N. , Ignatenko A. V. , Krayushkin M. M.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Synthesis of Stable Sulfines by Oxidation of Chlorodithioformates.
Authors: El‐Sayed Ibrahim
Published: September 2004

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Allenes and Transition Metals: A Diverging Approach to Heterocycles.
Authors: Brummond Kay M. , Mitasev Branko
Published: September 2004

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Microwave‐Assisted Elimination Reaction of trans‐4‐(4‐Fluorophenyl)‐3‐chloromethyl‐1‐methylpiperidine on Alumina.
Authors: Navratilova Hana , Kriz Zdenek , Potacek Milan
Published: September 2004

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Rearrangement of Pyrrolines Derived from the Birch Reduction of Electron‐Deficient Pyrroles: Radical Ring‐Expansion to Substituted Tetrahydropyridines.
Authors: Turner Peter G. , Donohoe Timothy J. , Cousins Rick P. C.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
2,5‐Dihydropyrazolo[4,3‐c]pyridin‐3‐ones: Functionally Selective Benzodiazepine Binding Site Ligands on the GABAA Receptor
Authors: Mitchinson Andrew , et al. et al.
Published: September 2004

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Electrochemical Reduction of 5‐Oxoindeno[1,2‐b]pyridinium Perchlorates in the Presence of Alkylating Agents.
Authors: Turovska B. , Muceniece D. , Lusis V. , Turovskis I. , Liepin'sh E. , Stradins J.
Published: September 2004

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Anomalous Beckmann Reaction of 4‐Aryl‐2,7,7‐trimethyl‐5‐oxo‐5,6,7,8‐tetrahydroquinoline Oximes in Polyphosphoric Acid. Part 1. New Synthesis of 1‐Ethoxycarbonyl‐2,5,5‐trimethyl‐5,6‐dihydro‐4H‐pyrido [2,3,4‐k,l]acridines.
Authors: Tolkunov S. V. , Khyzhan A. I. , Dulenko V. I.
Published: September 2004

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Syn‐2,3‐Disubstituted‐2,3‐dihydro‐1,4‐benzoxathiin Rings: Preparation from Quinone Ketals and 2‐Mercaptoethanols.
Authors: Dormer Peter G. , et al. et al.
Published: September 2004

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6‐Arylamino‐7‐chloro‐quinazoline‐5,8‐diones as Novel Cytotoxic and DNA Topoisomerase Inhibitory Agents.
Authors: Park Hyen Joo , Kim Young‐Shin , Kim Jin Sung , Lee Eun‐Jin , Yi You‐Jin , Hwang Hye Jin , Suh Myung‐Eun , Ryu Chung‐Kyu , Lee Sang Kook
Published: September 2004

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A Convenient Procedure for the Synthesis of Substituted 3‐α‐Haloalkyl‐5,6‐dihydro‐4H‐1,2‐oxazines.
Authors: Klenov Michael S. , Lesiv Alexey V. , Khomutova Yulya A. , Nesterov Ivan D. , Ioffe Sema L.
Published: September 2004

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2‐Hetaryl Derivatives of 3‐Oxo‐3,4‐dihydro‐2H‐1,4‐benzothiazine.
Authors: Nazarenko Konstantin G. , Shtil Nataliya A. , Chernega Alexander N. , Lozinskii Miron O. , Tolmachev Andrey A.
Published: September 2004

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Rhodium(I)‐Catalyzed Ene‐Allene Carbocyclization Strategy for the Formation of Azepines and Oxepins.
Authors: Brummond Kay M. , Chen Hongfeng , Mitasev Branko , Casarez Anthony D.
Published: September 2004

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Metal‐Catalyzed Di‐tert‐butylsilylene Transfer: Synthesis and Reactivity of Silacyclopropanes.
Authors: Cirakovic Jelena , Driver Tom G. , Woerpel K. A.
Published: September 2004

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Preparation of Vinylsilanes Through the Reaction of Polyhalides with α‐Halogen Substituted Allylsilanes Catalyzed by Copper(I) Chloride.
Authors: Mitani Michiharu , Masuda Masayuki , Inoue Akihiko
Published: September 2004

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Self‐Assembly of Cage Structure. Part 16. One‐Step Synthesis and Structure of a Tricyclic Trislactone with C3 Symmetry.
Authors: Kostyanovsky Remir G. , Krutius Oleg N. , Stankevich Andrey A. , Vilkov Lev V. , Atavin Evgenii G. , Vishnevsky Yuriy V. , Ivanov Arkadii A.
Published: September 2004

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A New Oxygenated Tricyclic Sesquiterpene from a Soft Coral of Nephthea Species of Andaman and Nicobar Coasts of Indian Ocean.
Authors: Rao Ch. Bheemasankara , Sekhar V. Chandra , Sarvani B. , Rao D. Venkata
Published: September 2004

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The First Synthesis of Glucosylgalactosyl Hydroxylysine (Glu‐Gal‐Hyl), an Important Biological Indicator of Collagen Turnover.
Authors: Allevi Pietro , Anastasia Mario , Paroni Rita , Ragusa Andrea
Published: September 2004

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Exploration of the P2—P3 SAR of Aldehyde Cathepsin K Inhibitors.
Authors: Deaton David N. , et al. et al.
Published: September 2004

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Preparative Synthesis of the Key Intermediate, (4R,5R)‐3‐Benzyloxymethyl‐4,5‐isopropylidenedioxycyclopent‐2‐enone for Carbocyclic Nucleosides.
Authors: Moon Hyung Ryong , Choi Won Jun , Kim Hea Ok , Jeong Lak Shin
Published: September 2004

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Organofluorine Compounds and Fluorinating Agents. Part 30. A Common Sugar as Model for Many‐Sided Natural Product Modification. From D‐Fructose via D‐Tagatose to 2‐C‐Chlorodifluoro‐methylated D‐Arabinopyranos‐5‐ulose Derivatives.
Authors: Miethchen Ralf , Tews Stefan , Shaw Arun K. , Roettger Svenja , Reinke Helmut
Published: September 2004

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Thioglycuronides: Synthesis and Application in the Assembly of Acidic Oligosaccharides.
Authors: van den Bos Leendert J. , Codee Jeroen D. C. , van der Toorn John C. , Boltje Thomas J. , van Boom Jacques H. , Overkleeft Herman S. , van der Marel Gijsbert A.
Published: September 2004

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Nitrone in L‐Lyxose Series: Cycloaddition Way for the Synthesis of New C‐α‐Fucosides.
Authors: Chevrier Carine , LeNouen Didier , Neuburger Markus , Defoin Albert , Tarnus Celine
Published: September 2004

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A Simple and Efficient Synthesis of (.+‐.)‐Mesembrine.
Authors: Chavan Subhash P. , Khobragade Dushant A. , Pathak Ashok B. , Kalkote U. R.
Published: September 2004

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On the Stability of Furanopyrimidine‐2‐one Bases in Oligonucleotides.
Authors: Jiao Guan‐Sheng , Burgess Kevin
Published: September 2004

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A Novel Asymmetric Route to Succinimides and Derived Compounds: Synthesis of the Lignan Lactone (+)‐Hinokinin.
Authors: Bennett D. Jonathan , Pickering Paula L. , Simpkins Nigel S.
Published: September 2004

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Biosynthetic Capacities of Actinomycetes. Part 31. Abyssomicins, Inhibitors of the para‐Aminobenzoic Acid Pathway Produced by the Marine Verrucosispora Strain AB‐18‐032.
Authors: Fiedler Hans‐Peter , et al. et al.
Published: September 2004

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In vitro Microbiological Characterization of a Novel Azalide, Two Triamilides and an Azalide Ketal Against Bovine and Porcine Respiratory Pathogens.
Authors: Norcia Laura J. L. , Silvia Annette M. , Santoro Sheryl L. , Retsema Jim , Letavic Michael A. , Bronk Brian S. , Lundy Kristin M. , Yang Bingwei , Evans Nigel A. , Hayashi Shigeru F.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
The First Total Synthesis of a Pyranonaphthoquinone Antitumor, BE‐54238B.
Authors: Tatsuta Kuniaki , Hirabayashi Tomokazu , Kojima Masazumi , Suzuki Yoshikazu , Ogura Takashi
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
EI‐2346, a Novel Interleukin‐1β Converting Enzyme Inhibitor Produced by Streptomyces sp. E‐2346. Part 2. Structure Elucidation.
Authors: Koizumi Fumito , Hasegawa Atsuhiro , Yoshida Mayumi , Matsuda Yuzuru , Nakanishi Satoshi
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
A Double Alkylation—Ring Closing Metathesis Approach to Spiroimines.
Authors: Brimble Margaret A. , Trzoss Michael
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Topochemical Transformation of Phyllosilicate Clay into Chlorite and Brucite.
Authors: Choy Jin‐Ho , Lee Sung‐Reol , Park Man , Park Gyeong‐Su
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Thiol‐Based SAHA Analogues as Potent Histone Deacetylase Inhibitors.
Authors: Suzuki Takayoshi , Kouketsu Akiyasu , Matsuura Azusa , Kohara Arihiro , Ninomiya Shin‐ichi , Kohda Kohfuku , Miyata Naoki
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Electrochemical Measurement of Dissolved Gases in Molten Metals
Authors: Fergus Jeffrey W.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Microemulsion: An Alternative Route to Preparing Supported Catalysts
Authors: Rojas S. , Eriksson S. , Boutonnet M.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Phase Stability and Phase Transformations in Pu—Ga Alloys
Authors: Hecker S. S. , Harbur D. R. , Zocco T. G.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Crystal Engineering on Controlled Crystal Arrays Using Hydrogen Bonding Biimidazolate Metal Complexes
Authors: Tadokoro Makoto
Published: September 2004

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Heteroatom‐Substituted Group 4 Bis(indenyl)metallocenes
Authors: Leino Reko , Lehmus Petri , Lehtonen Ari
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
1‐Substituted 5‐Alkyl(aryl)sulfanyltetrazoles and Their Derivatives
Authors: Koldobskii G. I. , Hrabalek A. , Esikov K. A.
Published: September 2004

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Synthesis of Fluorinated Amino Acids
Authors: Qiu Xiao‐Long , Meng Wei‐Dong , Qing Feng‐Ling
Published: September 2004

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Oxidative Synthesis of α‐Amino Nitriles from Tertiary Amines.
Authors: North Michael
Published: September 2004

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Formation of Five‐ and Six‐Membered Heterocyclic Rings by Radical Cyclization
Authors: Majumdar Krishna C. , Mukhopadhyay Partha P. , Basu Pradipta K.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
AMPA Receptor Ligands: Synthetic and Pharmacological Studies of Polyamines and Polyamine Toxins
Authors: Stroemgaard Kristian , Mellor Ian
Published: September 2004

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Generation and Reactions of Selenium Isologues of Enolate Ions
Authors: Murai Toshiaki
Published: September 2004

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The Pharmacology of Commonly Used Chemical Agents
Authors: Naguib Mohamed
Published: September 2004

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The Significance of Vasoactive Intestinal Peptide in Immunomodulation
Authors: Delgado Mario , Pozo David , Ganea Doina
Published: September 2004

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A Review of Marine Environmental Contaminant Issues in the North Pacific: The Dangers and How to Identify Them
Authors: Macdonald Robie W. , Morton Brian , Johannessen Sophia C.
Published: September 2004

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Metal‐Catalyzed Reactions of Diborons for Synthesis of Organoboron Compounds
Authors: Ishiyama Tatsuo , Miyaura Norio
Published: September 2004

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N2O Reduction by the μ4‐Sulfide‐Bridged Tetranuclear Cuz Cluster Active Site.
Authors: Chen Peng , Gorelsky Serge I. , Ghosh Somdatta , Solomon Edward I.
Published: September 2004

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Bionanotechnology Based on Silica Nanoparticles
Authors: Tan Weihong , Wang Kemin , He Xiaoxiao , Zhao Xiaojun Julia , Drake Timothy , Wang Lin , Bagwe Rahul P.
Published: September 2004

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Biology and Chemistry of the Inhibition of Nitric Oxide Synthases by Pteridine‐Derivatives as Therapeutic Agents
Authors: Matter Hans , Kotsonis Peter
Published: September 2004

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Plant Proteome Analysis by Mass Spectrometry: Principles, Problems, Pitfalls and Recent Developments
Authors: Newton Russell P. , Brenton A. Gareth , Smith Chris J. , Dudley Edward
Published: September 2004

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Gas‐Phase Polar Cycloadditions
Authors: Eberlin Marcos N.
Published: September 2004

For Abstract see ChemInform Abstract in Full Text.
Cross‐sectional and longitudinal comparisons of health‐related quality of life between patients with prostate carcinoma and matched controls
Authors: Hoffman Richard M. , Gilliland Frank D. , Penson David F. , Stone S. Noell , Hunt William C. , Potosky Arnold L.
Published: September 2004

BACKGROUND

Prostate carcinoma and treatments affect health‐related quality of life (HRQOL). The authors prospectively compared prostate and general HRQOL between prostate carcinoma cases and an age‐matched and ethnicity‐matched control group.

METHODS

The case cohort consisted of 293 men with localized prostate carcinoma who were selected randomly from the population‐based New Mexico Tumor Registry, and the control cohort consisted of 618 men who were selected randomly from administrative databases and matched for age and ethnicity. Subjects completed a baseline survey of demographics, socioeconomic status, comorbidity, and prostate and general HRQOL. Also, 210 cases (71.7%) and 421 controls (67.8%) completed a follow‐up survey 5 years later. Multinomial logistic regression models compared baseline characteristics as well as 5‐year general HRQOL outcomes measured by selected domains of the Medical Outcomes Study SF‐36. The authors used a mixed‐model repeated‐measures analysis of variance and multinomial regression analyses to compare longitudinal changes in urinary, bowel, and sexual function between groups.

RESULTS

At baseline, patients with prostate carcinoma had better urinary control and sexual function than controls. Over 5 years, sexual function declined significantly among controls, although urinary function remained stable. However, patients with cancer subsequently reported significant declines in both domains and were left with much worse function and more bother than controls. Bowel function and general HRQOL were similar for both groups at follow‐up.

CONCLUSIONS

Prostate carcinoma treatment led to significant 5‐year declines in urinary and sexual function that far exceeded age‐related changes in controls. Patients with cancer had significantly worse function and more bother than controls for these disease‐specific domains of HRQOL. Bowel function and general HRQOL were not affected by cancer status. Cancer 2004. Published 2004 American Cancer Society.
Prognostic factors and long‐term survivorship in patients with recurrent or metastatic carcinoma of the head and neck
Authors: Argiris Athanassios , Li Yi , Forastiere Arlene
Published: September 2004

BACKGROUND

The current study was conducted to identify prognostic factors and report the characteristics of long‐term survivors in patients with recurrent or metastatic carcinoma of the head and neck who were treated with cisplatin‐based combination chemotherapy in two randomized, Phase III trials conducted by the Eastern Oncology Cooperative Group (ECOG) (E1393 and E1395).

METHODS

The authors analyzed prognostic factors for response and survival by combining data from the E1393 trial, which compared cisplatin plus paclitaxel at two dose levels, with data from the E1395 trial, which compared cisplatin plus paclitaxel with cisplatin plus 5‐fluorouracil (5‐FU), using logistic regression and Cox regression models.

RESULTS

A total of 399 eligible patients were included. The median follow‐up was 4.7 years. The 1‐year overall survival (OS) rate for all patients was 32%, the median OS was 7.8 months, and the objective response rate was 32%. On multivariate analysis, the following were found to be independent unfavorable predictors of objective response: weight loss of > 5%, an ECOG performance status of 1 (vs. 0), residual disease at the primary tumor site, a primary tumor site other than the oropharynx, prior radiation therapy (RT) (P = 0.056), and well/moderate tumor cell differentiation (P = 0.067). Independent unfavorable prognostic factors for OS were weight loss, an ECOG performance status of 1 (vs. 0), well/moderate tumor cell differentiation, a primary tumor in the oral cavity or hypopharynx, and prior RT. The following were found to be independent unfavorable prognostic facotrs for time to disease progression: well/moderate tumor cell differentiation, a oral cavity or hypopharyngeal primary tumor, and prior RT. Patients with ≤ 2 adverse prognostic factors were reported to have a median OS of 1 year, whereas patients with 3–5 adverse prognostic factors were found to have a median OS of 0.5 years (P < 0.0001). Forty‐nine patients (12%) survived for ≥ 2 years and 6 patients were alive at 5 years. Two‐year survivors were more likely to have achieved an objective response to chemotherapy, have poor tumor cell differentiation, be white, have an ECOG performance status of 0, and have received no prior RT.

CONCLUSIONS

Clinical parameters and tumor cell differentiation appear to be strong pretreatment predictors of outcome in patients with carcinoma of the head and neck and should be considered in the design of future randomized trials. A small percentage of patients with recurrent head and neck carcinoma can achieve long‐term survival. Cancer 2004. © 2004 American Cancer Society.
Uterine serous and grade 3 endometrioid carcinomas
Authors: Boruta David M. , Gehrig Paola A. , Groben Pamela A. , Bae‐Jump Victoria , Boggess John F. , Fowler Wesley C. , Van Le Linda
Published: September 2004

BACKGROUND

Serous components within endometrial carcinoma are reportedly poor prognosticators. However, to the authors' knowledge the percentage of tumors which must be comprised of a serous component in order to affect outcome is unknown. The authors compared overall survival (OS) in women with endometrial carcinomas comprised of various percentages of uterine serous carcinoma (USC) with that of women with International Federation of Gynecology and Obstetrics (FIGO) Grade 3 endometrioid carcinoma (G3EC) to determine whether outcomes varied between these two poorly differentiated histologies.

METHODS

Data concerning women with either G3EC or USC who were diagnosed between January 1990 and November 2000 were collected retrospectively. Cases were reviewed to confirm diagnosis and estimate the fraction of tumor comprised of USC. Variables assessed included patient age and race, tumor stage, and lymphovascular space invasion. Associations between variables were tested using the Fisher exact test. The Kaplan–Meier method was used to evaluate OS with comparisons performed using the log‐rank test.

RESULTS

Fifty‐two women with G3EC and 87 women with USC were identified. The OS of women with tumors comprised of > 50% USC was found to be significantly worse compared with women with G3EC (hazard ratio [HR] of 2.4; 95% confidence interval [95% CI], 1.2–5.2). Women with USC were more likely to present with extrauterine disease (odds ratio of 2.2; 95% CI, 1.1–4.5). The 5‐year survival rate for women with G3EC was 75% compared with 41% for women with tumors that were > 50% USC (P = 0.01). There was a significant trend toward a worse OS in women with even 10% USC compared with women with G3EC.

CONCLUSIONS

USC involving > 50% of an endometrial carcinoma was found to be predictive of worse OS compared with the OS of women with G3EC. In patients with early‐stage disease, a trend toward a worse prognosis was found to exist when USC comprised even 10% of a tumor. Investigation into the treatment of endometrial carcinoma should include and document tumors with any percentage comprised of USC. Cancer 2004. © 2004 American Cancer Society.
Localization and connectivity of the lateral amygdala in anuran amphibians
Authors: Moreno Nerea , González Agustín
Published: September 2004

On the basis of chemoarchitecture and gene expression patterns in the amphibian amygdaloid complex, new subdivisions have been proposed and compared with their counterparts in amniotes. Thus, a portion of the ventral pallium of anurans has been tentatively named “lateral amygdala” (LA) and compared with the basolateral complex of mammals. To strengthen the putative homology, we have analyzed the pattern of afferent and efferent connections of the LA in the anurans Rana perezi and Xenopus laevis. Tract‐tracing techniques with dextran amines were used under in vivo and in vitro conditions. The results showed important connections with the main olfactory bulb, via the lateral olfactory tract. In addition, abundant intratelencephalic connections, via the rostral branch of the stria terminalis, were revealed, involving mainly the basal ganglia, septal nuclei, bed nucleus of the stria terminalis, and especially other amygdaloid nuclei. Nontelencephalic connections were found from the dorsal thalamus and parabrachial area and, in particular, from the hypothalamus through the caudal branch of the stria terminalis. All these results strongly suggest that the LA in anurans is a multimodal area in the ventral pallium that shares many hodological features with the amygdaloid ventropallial derivatives of the basolateral complex of amniotes. J. Comp. Neurol. 479:130–148, 2004. © 2004 Wiley‐Liss, Inc.
Distribution of zincergic neurons in the mouse forebrain
Authors: Brown Craig E. , Dyck Richard H.
Published: September 2004

Synaptically released zinc is thought to play an important role in neuronal signaling by modulating excitatory and inhibitory receptors and intracellular signaling proteins. Consequently, neurons that release zinc have been implicated in synaptic plasticity underlying learning and memory as well as neuropathological processes such as epilepsy, stroke, and Alzheimer's disease. To characterize the distribution of these neurons, investigators have relied on a technique that involves the retrograde transport of zinc–selenium crystals from axonal boutons to the cell bodies of origin. However, one major problem with this method is that labeling of cell bodies is obscured by high levels of staining in synaptic boutons, particularly within forebrain structures where this staining is most intense. Here, we used a modification of the retrograde labeling method that eliminates terminal staining for zinc, thereby enabling a clear and comprehensive description of these neurons. Zincergic neurons were found in all cerebral cortical regions and were arranged in a distinct laminar pattern, restricted to layers 2/3, 5, and 6 with no labeling in layer 4. In the hippocampus, labeling was present in CA1, CA3, and the dentate gyrus but not in CA2. Labeled cell bodies were also observed in most amygdaloid nuclei, anterior olfactory nuclei, claustrum, tenia tecta, endopiriform region, lateral ventricle, lateral septum, zona incerta, superior colliculus, and periaqueductal gray. Moreover, retrograde labeling was also noted in the dorsomedial and lateral hypothalamus, regions that previously were thought to be devoid of neurons with a zincergic phenotype. Collectively these data show that zincergic neurons comprise a large population of neurons in the murine forebrain and will provide an anatomical framework for understanding the functional importance of these neurons in the mammalian brain. J. Comp. Neurol. 479:156–167, 2004. © 2004 Wiley‐Liss, Inc.
Expression of Cux‐1 and Cux‐2 in the subventricular zone and upper layers II–IV of the cerebral cortex
Authors: Nieto Marta , Monuki Edwin S. , Tang Hua , Imitola Jaime , Haubst Nicole , Khoury Samia J. , Cunningham Jim , Gotz Magdalena , Walsh Christopher A.
Published: September 2004

Little is known about how neurons in the different layers of the mammalian cerebral cortex are specified at the molecular level. Expression of two homologues of the Drosophila homeobox Cut gene, Cux‐1 and Cux‐2, is strikingly specific to the pyramidal neurons of the upper layers (II–IV) of the murine cortex, suggesting that they may define the molecular identity of these neurons. An antibody against Cux‐1 labels the nucleus of most of the postmitotic upper layer neurons but does not label parvoalbumin‐positive cortical interneurons that derive from the medial ganglionic eminence. Cux‐1 and Cux‐2 represent early markers of neuronal differentiation; both genes are expressed in postmitotic cortical neurons from embryonic stages to adulthood and in the proliferative regions of the developing cortex. In precursors cells, Cux‐1 immunoreactivity is weak and diffuse in the cytoplasm and nucleus of ventricular zone (VZ) cells, whereas it is nuclear in the majority of bromodeoxyuridine (BrdU)‐positive subventricular zone (SVZ) dividing cells, suggesting that Cux‐1 function is first activated in SVZ cells. Cux‐2 mRNA expression is also found in the embryonic SVZ, overlapping with BrdU‐positive dividing precursors, but it is not expressed in the VZ. A null mutation in Pax‐6 disrupts Cux‐2 expression in the SVZ and Cux‐1 and Cux‐2 expression in the postmigratory cortical neurons. Thus, these data support the existence of an intermediate neuronal precursor in the SVZ dedicated to the generation of upper layer neurons, marked specifically by Cux‐2. The patterns of expression of Cux genes suggest potential roles as determinants of the neuronal fate of the upper cortical layer neurons. J. Comp. Neurol. 479:168–180, 2004. © 2004 Wiley‐Liss, Inc.
Expression of dopamine and vesicular monoamine transporters and differential vulnerability of mesostriatal dopaminergic neurons
Authors: González‐Hernández Tomás , Barroso‐Chinea Pedro , de la Cruz Muros Ignacio , del Mar Pérez‐Delgado María , Rodríguez Manuel
Published: September 2004

Numerous studies suggest that the dopamine transporter (DAT), responsible for dopamine reuptake, may act as a vulnerability factor in the pathogenesis of Parkinson's disease (PD) and the vesicular monoamine transporter (VMAT2), responsible for its vesicular storage, as a neuroprotective factor. However, the relevance of each on the differential vulnerability of midbrain DA cells remains uknown. Here we studied the relationship between the expression pattern (mRNA and protein) of both transporters and the differential vulnerability of midbrain DA cells in a model of PD (intracerebroventricular injection of 6‐OHDA in rats) and in monkey and human midbrain. Our results revealed that the expression patterns for VMAT2 mRNA and protein and DAT mRNA are similar, with the highest levels in the rostromedial region of substantia nigra (SNrm), followed by the caudoventral region of SN (SNcv), the ventral tegmental area and pigmented parabrabraquial nucleus (VTA/PBP), and finally the linear and interfascicular nuclei (Li/IF). In contrast, the expression of DAT protein in rats, monkeys, and humans followed a caudoventrolateral‐to‐rostrodorsomedial decreasing gradient (SNcv > SNrm > VTA/PBP > Li/IF), matching the degeneration profile observed after intracerebroventricular injection of 6‐OHDA and in PD. In addition, DAT blockade made all midbrain DA cells equally resistant to 6‐OHDA. These data indicate that DAT protein levels, but not DAT mRNA levels, are closely related to the differential vulnerability of midbrain DA cells and that this relationship is unaffected by the relative levels of VMAT2. Furthermore, the difference between DAT mRNA and protein profiles suggests internuclear differences in its posttransductional regulation. J. Comp. Neurol. 479:198–215, 2004. © 2004 Wiley‐Liss, Inc.
Experience‐dependent activation of extracellular signal‐related kinase (ERK) in the olfactory bulb
Authors: Mirich Jennifer M. , Illig Kurt R. , Brunjes Peter C.
Published: September 2004

Protein kinase‐mediated signaling cascades play a fundamental role in translating extracellular signals into cellular responses in CNS neurons. The mitogen‐activated protein kinase / extracellular signal‐regulated kinase (MAPK/ERK) pathway participates in regulating diverse neuronal processes such as proliferation, differentiation, survival, synaptic efficacy, and long‐term potentiation by inducing cAMP‐response element (CRE)‐mediated gene transcription. Central olfactory structures show plasticity throughout the lifespan, but the role of the MAPK/ERK pathway in odor‐evoked activity has yet to be determined. Therefore, we examined the effect of odorant exposure and early postnatal deprivation on ERK activity. We found that odor stimulation induced ERK phosphorylation, that activation of the ERK pathway was decreased with early postnatal deprivation, and that ERK phosphorylation was subsequently increased by restoring stimulation. Further, locations of ERK activation in bulbar neurons after exposure to single odorants corresponded to odor‐evoked activity patterns found with other measures of activity in the bulb. Finally, due to the cytoplasmic location of pERK, activated dendrites belonging to the primary excitatory output neurons of the bulb were observed following a single odor exposure. The results indicate that the MAPK/ERK pathway is activated by odorant stimulation and may play an important role in developmental sensory plasticity in the olfactory bulb. J. Comp. Neurol. 479:234–241, 2004. © 2004 Wiley‐Liss, Inc.