bluuebunny/crossref_metadata_2025 huggingface dataset:
GREEN ENTREPRENEURSHIP AMONG STUDENTS
Authors: MOICEANU Georgiana , POPESCU Mirona Ana Maria , BARBU Andreea , MOICEANU Anca Daniela
Published: December 2023

Students are increasingly launching firms that put sustainability and environmental responsibility first, a trend known as "green entrepreneurship." Students are proactively starting businesses that provide eco-friendly goods or services as they become more aware of the significance of addressing urgent environmental concerns. Students that engage in green entrepreneurship not only support sustainable practices but also develop their innovative, artistic, and leadership abilities. The finding revealed that they are willing to address more sustainable businesses to ensure future for others to come, but there are still data about green entrepreneurship that are unknown or difficult to address. In addition, the results revealed that green entrepreneurship could constitute a measure for helping the economy of a country. Students are bringing about change and defining a better future by fusing their entrepreneurial energy with their passion for environmental problems. In addition to improving their local communities, these young business owners are also encouraging others to adopt sustainable habits and advance a culture that values the environment.
DIGITAL TOOLS FOR THE RESILIENCE OF THE HEALTHCARE SECTOR DURING THE COVID-19 PANDEMIC: OVERVIEW
Authors: STANCIU Dana-Mihaela , MILITARU Gheorghe
Published: December 2023

In times of crisis, organizations need to quickly adapt to unexpected disruptions and prevent the halt of their ongoing workflows. The COVID-19 pandemic had wracked havoc across economies worldwide, and the associated toll of lost lives, together with the incommensurable financial losses on the global markets will always be remembered as the defining grim consequences of this crisis that humanity faced. As a side effect, the pressure that it exerted over businesses worldwide has given rise to new ways on how digital tools and can be leveraged to combat intrinsic pandemic effects, such as limited mobility of people and goods, or various types of supply chain inconsistencies. As a result, in the context of medicine, the COVID-19 pandemic has accelerated the transition to the concept of “digital health” in health care systems worldwide. In this work we provide an overview of various digital tools and solutions reported in the frame of public and private health care sectors, which have been successfully used during the COVID-19 pandemic as solutions for the resilience of healthcare sectors worldwide.
IDENTIFICATION OF CRITICAL FACTORS FOR IMPROVINF THE SECURITY OF TELECOMMUNICATION SYSTEMS
Authors: ANCU Alina-Elena , BARBU Andreea
Published: December 2023

The objective of this study is to identify the vulnerabilities that can affect the security of telecommunication systems and to determine the critical factors for improving the security of telecommunication systems. The authors conducted a focus group as qualitative method used for this research with twelve specialists who have a technical position and a vast experience in the telecommunication industry to highlight the critical factors for improving the security of the telecommunication systems. Based on the given answers by the specialists, there were identified thirty-one factors that can be spitted in three categories: technological factors, human factors, and legal factors. For the research limitation, the factors were strictly identified based on the given answers by the selected participants to the focus group. As the practical implication, the authors highlighted first the factors that were defined as vulnerabilities for the security of telecommunication system and determined the critical factors that must be monitored on a regular basis by every company to maintain a safe telecommunication system. As the value of this paper, the authors selected twelve important specialists who have a vast experience in this area and using their answers, it was designed a model of the critical factors that will help every company to improve their security capabilities.
“LEMON” PERCEPTIONS? A COMPARATIVE ANALYSIS OF SECOND-HAND CARS’ PRICES IN ROMANIA AND GERMANY
Authors: GHITA Vladimir , IORGA Denis , DUTULESCU Andreea , DASCALU Mihai , MILITARU Gheorghe
Published: December 2023

“Lemon” perceptions refer to beliefs about the existence of low-quality second-hand cars in the market. Such beliefs, as part of a wider socio-economic phenomenon named adverse selection, manifest themselves through risk-aversion attitudes, for instance, a decreased willingness to pay high prices for any used car, regardless of its actual quality. In the current work, we argue that the prevalence of “lemon” perceptions can be explored by comparing the prices of similar second-hand cars in two different markets. To this extent, the current work advances a comparative analysis of the selling prices of similar second-hand cars in Romania and Germany by using data from online platforms dedicated to selling second-hand vehicles. Our results show, by examining the price differences of a diverse range of second-hand cars, that the price of the same car tends to be higher in the Romanian market than in the German market, irrespective of usage, but not of the brand. These results are both of practical value to stakeholders in the second-hand car market (i.e., buyers, sellers, policymakers) and of theoretical value as regards researching the adverse selection market mechanism.
COMPLEX NATURE OF THE EFFICIENCY OF SOCIAL INVESTMENTS IN BULGARIA
Authors: ANTONOVA Diana , TODOROVA Ana
Published: December 2023

Social investments implement non-economic criteria in investment deci­sions and thus change the long-term goals of business organisations. They have a long-term perspective and strive for sustainable and socially responsible results. While traditional investments are focused solely on economic profit, social invest­ments promote, on the one hand, economic growth and profit and, on the other – investment in people and society. The article aims to illuminate the multifaceted nature of social investments' efficiency and show that the leading indicators of its effectiveness should be tailored to the actual needs of society and the social order. The report presents a three-stage process of implementing the social investments efficiency assessment, giving good examples from Bulgaria. The study also intro­duces a matrix of interaction between identified evaluation indicators, which creates prerequisites and conditions for the success of a business organisation.
ASPECTS OF THE ECONOMIC AND SOCIAL EFFICIENCY OF CORPORATE SOCIAL RESPONSIBILITY IN BULGARIA
Authors: TODOROVA Ana , ANTONOVA Diana
Published: December 2023

This article examines problems of an institutional nature related to cor­porate social responsibility and the socialisation of labour. At the beginning of the third decade of the XXI century, the role of business in the public life of Bulgaria is increasing. As a result, its influence on the economic and social spheres is becoming more and more noticeable. Therefore, it is essential to analyze the possibilities and methods for state regulation of social responsibility, primarily from the point of view of the design of institutions related to corporate social activity and social invest­ments. On the other hand, the obligations companies voluntarily undertake to imple­ment social policy in the interest of stakeholders along the five-level chain to pro­duce sustainable strategic economic-social solutions are also tracked.
ROMANIAN TECHNICAL UNIVERSITIES: A VIEW OF THE INNOVATION SYSTEM THROUGH ERASMUS+ PROGRAMME
Authors: MILITARU Andreea Maria Gabriela , KURT Atil , FLEACĂ Bogdan
Published: December 2023

This paper is analysing within the framework of innovation systems the characteristics through the Erasmus+ programme for higher education for technical universities in Romania. The indicators are providing insights about the innovation system implications. The data was analysed using Excel for statistical measurements and comparisons. The Erasmus+ programme was implemented 36 years ago having as scope the mobility of students among EU countries, evolving throughout time and spreading even all over the world. One of the strengths of this successful programme is the innovative character based on cooperation and collaboration between entities. Research and development are one of the key activities helping the business environment to move on. Universities mastering the research and development activities and taking advantage of the exchange experience of students and staff can consider that they have some qualitative inputs over the performance of the business environment. The analysis of this paper could bring to fellow researchers, the business environment, and academia a general overview of the development of the trend of outbound and inbound mobilities and the implications over the innovation cluster at the regional level. The purpose of this paper is to identify the trends of the Erasmus+ programme Higher Education mobility and main characteristics showing the character of regional innovation systems.
The Experience of Using the Discounting Matrix in Patients with Eating Disorders
Authors: Gorovaya Tatyana Viktorovna , Lifshitz Margarita Осиповна
Published: December 2023

In the article the authors present the experience of using TA (Transactional Analysis) to identify discounting as a mechanism of psychological protection and describe the Discounting Matrix created by Ken Mellor and Eric Schiff (Sigmund) at the Cathexis Institute. The authors show their experience of using the Discounting Matrix in clinical practice. Also the article presents possible questions that might facilitate the diagnosis of levels of discounting in patients with eating disorders. The authors show the practical value of using this approach for subsequent psychotherapeutic treatment.
Features of Interaction in Online Counseling from the Standpoint of Transactional Analysis
Authors: Starobinskaya-Koveshnikova Ekaterina I.
Published: December 2023

This paper is based on the speech at the MIR-TA (International Institute of Development Transactional Analysis, IIDTA) Student Conference in 2023. The article considers the phenomenon of virtual communication in the modality of Transactional Analysis, describes the features of virtual communication, both among specialists of helping professions and free internet users. Based on Eric Berne’s theory of satisfying hunger (thirst) for structure, recognition and stimulus, the author analyzes virtual ways to satisfy these motivators. The article describes in detail each of the six ways of structuring time in virtual space, as well as the process of interaction among internet users, and how virtual interaction affects real contacts. The author also speaks about the features of an administrative contract for online counseling in working with a client. Also, virtual communication is considered as a tool for creating a favorable atmosphere for personal development and therefore a way to satisfy the client’s stimulus hunger is proposed, and practical recommendations are given. The author suggests taking a more conscious look at virtual communication and using it as a tool for personal development in a rapidly changing reality.
The Topic of Money in the Life of a Specialist of Helping Professions
Authors: Balakhonova Daria A.
Published: December 2023

This article examines from different angles the issues of choosing a cost of payment for psychological counseling, the role of a therapist’s own life script and its impact on the personal financial sphere. It is assumed that the topic of money, consciously or not, is often avoided in discussions by the professional community of psychologists and other helping professionals. The author suggests that the reasons for such avoidance are: the cultural script, the history of the development of psychology in the post-Soviet space, the peculiarities of the ethics of the profession and higher professional education. The author proposes methods for calculating the cost of one consultation and a scheme for studying personal financial blocks in a psychotic script of a psychologist. An algorithm is presented that allows decontamination of the Adult ego state through working with proverbs, sayings and family myths using phenomenological questions and subsequent analysis.
Psychoterapeutic Work with The Trauma Of Immigration in Transactional Analysis Approach
Authors: Lukianova Liliia G.
Published: December 2023

This article contains the author’s reflections on how looking at emigration through the lens of traumatic experience can help expand the understanding of a client’s life script and support the client in overcoming difficulties in adaptation in a new country. The meaning of «trauma» allows us to draw an analogy between the emigration experience and those possible changes in the life script that the emigration provokes. The emigration experience can greatly contribute to regression to the Child ego state, which can also interfere with the adaptation of the client. The article considers the possible causes of regression and how this may affect the design of new decisions in the present and future. The article offers the practical experience of working with emigrants, which reflects the tendency to strengthen the driver ”Be strong”, and also explains the reasons for such behavior among respondents, participants of the experiment. The author suggests using the existential position ”I’m OK — You’re OK” as a formula for overcoming cultural difficulties of adaptation and as a lens for perceiving the difference of cultures during the process of mastering a new system of norms and rules. Awareness of the practical experience acquired through emigration can help a person overcome difficulties in adapting to a new country. The article was prepared on the basis of a speech at the MIR-TA (International Institute of Developing TA) Conference in 2023.
”This is a Completely Different View of an Examination, Which is Not Peculiar to Our Ideas About It”
Authors: Orlova Tatiana N.
Published: December 2023

This article presents an interview with Natalia Shikina, a translator who works on the examinations for obtaining CTA-P status. Natalia shares her experience of working as a translator on the oral part of the examinations: reveals the subtleties and peculiarities of passing the examination, tells what the written and oral examinations include, what kind of atmosphere awaits candidates for CTA status, as well as what the translator should be prepared for and what to provide for everything to be successful, how to prepare technically and emotionally. The interview also touches on the question of what level of English proficiency a translator should have to work on the CTA examination. The interview from the point of view of a translator, not an examinee, will allow readers, including those preparing for obtaining the CTA status, to look at the examination from the other side and get a deeper understanding of the process.
The Theory of Strokes from the Unconditional Position ”I’m — OK, You’re — OK” on the Example of the TV Series ”Ted Lasso”
Authors: Pushkaryov Alexander Yu.
Published: December 2023

This article presents an analysis of the theory of strokes used in the framework of Transactional Analysis, with an illustration of this theory on the example of the TV series “Ted Lasso” (2020-2023). The main character of this story uses all kinds of strokes described by Mary and Robert Goulding, and also acts as a carrier of the unconditional existential position “I’m — OK, You’re — OK”, which is healing both within the framework of human relationships and within the framework of the psychotherapeutic process. The author draws interesting parallels, noting the similarity between the group psychotherapeutic process and the work of a coach in a football team.
Empresas del IBEX-35: Consejeras y directivas de alta dirección
Authors: Curós-Vilà Pilar , Crespi-Vallbona Montserrat , Boria Reverter Josefa , Gonzalez Navarro Ana M.
Published: December 2023

La presencia de mujeres en la empresa es cada vez más común y necesaria para lograr una mayor equidad de género en el ámbito laboral. A lo largo de la historia, las mujeres se han enfrentado a barreras y discriminación en el mundo laboral, pero hoy en día, la situación está cambiando gracias a las luchas feministas, a una mayor conciencia social sobre la importancia de la igualdad de oportunidades y al apoyo legislativo.
Las mujeres aportan una visión y perspectiva diferente en la organización, lo que puede repercutir en una mayor creatividad, innovación y, por ende, rentabilidad.
Sin embargo, todavía existen obstáculos y desafíos que enfrentan las mujeres en el ámbito laboral, como la brecha salarial de género, la falta de representación en cargos directivos y de liderazgo, y la discriminación basada en estereotipos de género.
Además, su presencia en cargos directivos y de liderazgo puede fomentar la diversidad y la inclusión en la empresa, por ello es importante conocer la incidencia de la mujer en las empresas que cotizan en el Índice bursátil IBEX-35. Para ello, se utiliza el análisis de datos secundarios de la Comisión Nacional del Mercado de Valores (CNMV) y se aplica el algoritmo de Pichat a partir de la distancia de Hamming para conocer esas actuaciones. De esta forma, se pretende determinar si se cumple con las recomendaciones de la normativa actual en este campo. Es importante seguir trabajando en la eliminación de estas barreras para lograr una mayor igualdad de oportunidades en el mundo laboral y promover el desarrollo profesional y personal de todas las personas, independientemente de su género.
La OSDE viajes Cuba: Una mirada a su proyección estratégica de cara al futuro
Authors: Souto Anido Lourdes , Odriozola Guitart Silvia
Published: December 2023

Las condiciones de incertidumbre en las que se desarrolla en la actualidad el turismo exigen que las empresas que operan en este sector incrementen sus propuestas de valor para los clientes, con el fin de mantener una posición competitiva en el mercado. En este contexto, la necesidad de avanzar en propuestas que mejoren la gestión de las organizaciones se convierte en una necesidad de máxima prioridad. En el caso de Cuba, ello adquiere mayor relevancia, teniendo en cuenta que la actividad turística constituye uno de los sectores estratégicos del desarrollo económico y social del país. De ahí que sus organizaciones empresariales requieran del perfeccionamiento continuo de sus mecanismos de gestión. El presente artículo propone el diseño estratégico para la OSDE Viajes Cuba, grupo empresarial que abarca cuatro agencias de viajes. Para ello se aplican herramientas como el Modelo VRIO y la Matriz DAFO. Dicho diseño se complementa con un Cuadro de Mando Integral (CMI), como herramienta de análisis de su desempeño de manera integral.
Frontiers of NIR Imaging
Authors: Ozaki Yukihiro , Ishigaki Mika
Published: December 2023

After a brief introduction to the technique, this review will discuss the state-of-the-art NIR imaging instrumentation and its applications, including applications of an ordinary NIR imaging system to solvent diffusion into a polymer. Other imaging applications discussed include the use of a portable NIR imaging system in the pharmaceutical industry, high-speed and wide-area monitoring of polymers, and imaging for fish embryos development research. Also discussed is an imaging-type two-dimensional Fourier spectroscopy (ITFS) system and its application to medaka (Japanese rice fish, Oryzias latipes) egg development. Finally, general perspectives on NIR imaging will be provided.
Measurement Uncertainty in Specific Hormone Tests
Authors: Akşit Murat , Terzioğlu Mustafa , Zeytinli Akşit Merve , Kansu Altan Tuba , İşbilen Başok Banu , Çolak Ayfer
Published: December 2023

Amaç: Klinik laboratuvarlarda yapılan kalite iyileştirme çalışmaları, doğru ve güvenilir hasta sonuçlarına ulaşılmasında hayati bir rol oynamaktadır. Ölçüm belirsizliği test sonuçlarının kalitesi ve güvenilirliği için önem arz etmektedir. Laboratuvar sonuçları doğal olarak belirsizlik içerdiğinden, ISO 15189 Akreditasyon Standartları, hasta sonuçlarının ölçüm belirsizliği ile birlikte rapor edilmesini önermektedir. Çalışmamızın amacı, laboratuvarımızda çalışılan spesifik hormon testlerinin doğruluk ve güvenirliğini arttırmak için ölçüm belirsizliğini belirleyip uluslararası kuruluşlar tarafından belirlenen toplam izin verilen hata (%TEa) değerleriyle karşılaştırmaktır.
Materyal ve Metod: Çalışmamız Sağlık Bilimleri Üniversitesi İzmir Tepecik Eğitim ve Araştırma Hastanesi Tıbbi Biyokimya Laboratuvarında gerçekleştirildi. Adrenokortikotropik hormon (ACTH), büyüme hormonu, insülin benzeri büyüme faktörü-1 (IGF-1), C-peptit, tiroglobulin, 25-hidroksi vitamin D ve parathormon (PTH) parametrelerinin ölçüm belirsizliklerini belirlemek için, Ekim - Aralık 2022 arasındaki 3 aylık iç kalite kontrol verileri ve Ocak - Aralık 2022 arasındaki 12 aylık dış kalite kontrol verileri kullanıldı. Testlerin ölçüm belirsizliği Nordtest kılavuzuna göre hesaplandı. Bu değerler, üç farklı uluslararası kuruluş tarafından belirlenen %TEa kriterlerine göre değerlendirilmiştir.

Bulgular: ACTH, büyüme hormonu, IGF-1, C-peptid, tiroglobulin, 25-hidroksi D vitamini ve PTH testlerinin ölçüm belirsizlikleri %95 güven aralığında seviye 1 için sırasıyla 11,53, 14,83, 12,35, 7,91, 18,18, 20,95, 15,69; seviye 2 için sırasıyla 10,99, 13,65, 13,15, 5,87, 17,24, 17,05, 16,56 olarak hesaplanmıştır. Seviye 3 için C-peptid, tiroglobulin ve PTH testlerinin ölçüm belirsizlikleri sırasıyla 6,98, 16,03 ve 15,51 idi.

Sonuç: Büyüme hormonu ve C-peptidin genişletilmiş ölçüm belirsizlikleri uluslararası kuruluşlar tarafından belirlenen %TEa değerlerinin altında tespit edilirken, ACTH ve IGF-1 testlerinin ölçüm belirsizlikleri her iki seviyede de Avustralya Kraliyet Patologlar Kurulu (RCPA) %TEa değerlerine kıyasla sınırda yüksek bulundu. Tiroglobulin, 25-hidroksi vitamin D ve PTH parametrelerinin ölçüm belirsizlikleri her iki seviyede de RCPA %TEa değerlerinden yüksek olmakla birlikte, diğer uluslararası kuruluşlar tarafından belirlenen %TEa değerlerinin altında saptandı.
Crohn's disease and clinical management today: How it does?
Authors: da Silva Júnior Ronaldo Teixeira , Apolonio Jonathan Santos , de Souza Nascimento Jessica Oliveira , da Costa Bruna Teixeira , Malheiro Luciano Hasimoto , Silva Luz Marcel , de Carvalho Lorena Sousa , da Silva Santos Cleiton , Freire de Melo Fabrício
Published: December 2023

Crohn’s Disease (CD) is an Inflammatory Bowel Disease and is characterized by an immune-mediated nature. Its etiology results from the interaction between genetic, enviromental and microbial factors. Regarding pathophysiology, it involves high levels of interleukin (IL)-12, IL-17, and Th1 profile, along with loss of tolerance mechanisms, an increase in pro-inflammatory interleukins, beyond the possibility to affect any part of the gastrointestinal tract. Its symptoms include abdominal pain, chronic diarrhea, weight loss, anorexia, and fatigue, as well as blood in the stool or rectum. Additionally, conditions comprising musculoskeletal, cutaneous, ocular, hepatic, and hematological alterations may be associated with this scenario and extra-intestinal presentation, such as erythema nodosum, anterior uveitis, osteoporosis, and arthritis can also occur. Today, clinical history, exams as fecal calprotectin, ileocolonocopy, and capsule endoscopy can be performed in the diagnosis investigation, along with treatments to induce and maintain remission. In this sense, anti-inflammatory drugs, such as corticosteroids, immunomodulators, and biological agents, as well as surgery and non-pharmacological interventions plays a role in its therapy. The aim of this review is to bring more current evidence to clinical management of CD, as well as to briefly discuss aspects of its pathophysiology, surveillance, and associated disorders.
Using national census data to facilitate healthcare research
Authors: Colwill Michael , Poullis Andrew
Published: December 2023

National censuses are conducted at varying intervals across both the developed and developing world and collect detailed data on a wide range of societal, economic and health questions. This immense volume of data has many potential uses in the field of healthcare research and can be utilised either in isolation or in conjunction with other information sources such as hospital records. At a governmental level census data can be used for healthcare service planning by providing accurate population density information but also, through the use of more detailed data collection, by helping to identify high-risk populations that may require increased resource allocation. It can also be a key tool in addressing and improving healthcare inequality and deprivation by both identifying those populations with poorer healthcare outcomes and through helping researchers to better understand the causes of this inequality. Similarly, it has utility when studying the complex causes of disease and assessing the success of strategies designed to tackle these aetiologies. However, the maximum benefit from these various uses can only be realised if the data collection and analysis processes utilised are robust and this requires that census bureaus regularly review and modify their methods in a transparent and thorough way.
Urine exosome mRNA-based test for monitoring kidney allograft rejection: Effects of sample transportation and storage, and interference substances
Authors: McFaul Matt , Ventura Chris , Evans Sean , Dundar Halil , Rumpler Marc J , McCloskey Christopher , Lowe Dave , Vlassov Alexandre V
Published: December 2023

BACKGROUND

Exosomes are 30-150 nm nanovesicles with sophisticated nucleic acids cargo, actively secreted by all cells within human body, and found in abundance in all body fluids, including urine. These extracellular vesicles have tremendous potential for next generation diagnostics, theoretically enabling noninvasive assessment of organ and tissue function via liquid biopsy analysis.

AIM

Recently, feasibility of an exosomal molecular test was demonstrated for post-organ transplant monitoring: Analysis of urine-derived exosomal mRNA cargo allowed early detection of kidney allograft rejection. Here, we further studied urine-derived exosomes and their mRNA content as a highly promising diagnostic modality. This included stability studies of urine samples and exosomal mRNA upon transportation from the point of collection to a centralized testing facility, short-term storage of urine at different conditions upon receipt till the point molecular assay is performed, and effects of various potentially interfering substances on the downstream quantitative polymerase chain reaction (qPCR) assay.

METHODS

The urine specimens were stored at various conditions and pre-processed in different ways. Next, samples were passed through the columns to capture all extracellular vesicles, the vesicles were lysed to release their content and the exosomal RNA was purified on the mini-columns, reverse transcription was performed, next pre-amplification, followed by a qPCR analysis for a panel of mRNA markers.

RESULTS

To ensure exosomal RNA integrity, the harvested urine specimens should be shipped refrigerated, by overnight delivery. Urine can next be stored at the test site for up to 1 wk at 4 °C, and long term should be frozen at -80 °C. Urine specimens must be centrifuge at low G-force to deplete cells and debris, to ensure consistent top results in downstream molecular assays. All commonly used medications (tacrolimus, cyclosporin A, mycophenolic acid, everolimus, sirolimus, ascomycin, teriflunomide) were tested and confirmed that they do not cause assay interference.

CONCLUSION

mRNA from urine-derived exosomes was shown to be stable across a broad range of conditions and produced accurate results when analyzed via qPCR assay for detection of kidney allograft rejection. We identified the most optimal conditions for every step of the process, ensuring pre-analytical sample integrity and robust qPCR results.
IN-SILICO DOCKING ANALYSIS OF SELECTED FLAVONOIDS AND PROTECTIVE ANTIGEN
Authors: Bakhtari A. , Gavanji S.
Published: December 2023

Abstract
Anthrax toxin released by virulent strains of the bacterium, Bacillus anthracis, plays key
factor in anthrax disease. The main purpose of this study was to investigate the interaction between four flavonoid ligands including Rhamnetin, Apigenin, Tectochrysin, Pinocembrin and protective antigens. Bioinformatics checking was done by means of Molegro virtual docker and Chimera 1.7. Also, in order for more accuracy, servers like Swiss Dock and BSP-SLIM, and all outputs obtained from this software were compared with each other. The results demonstrated that Apigenin interacted with the Glu117 which is crucial part of binding to its ligand with -12.3453 kca/mol. Also, the
highest Fullfitness among these four ligands attributed to Rhamnetin with -994.80 kcal/mol and the ΔG =-7.06 kcal/mol. Results demonstrated that every four ligands possessed interaction with protective antigen and so have inhibitory effect on its interaction with cell membranes but the inhibitory activity of Apigenin and Rhamnetin in interaction is stronger than others flavonoids. Results shown above bring up laboratory studies based on these flavonoids in order to produce an efficacious drug against anthrax.
Revolutionizing Organ Donation With Blockchain Technology
Authors: Momaya Vedant Jayesh , Hameed BM Zeeshan , Adhikari Kinju , Das Mayukh , Talyshinskii Ali , Naik Nithesh , Somani Bhaskar K , Chlosta Piotr , Rai Bhavan Prasad
Published: December 2023

Amidst a critical shortage in organ donations, with over 120,000 individuals on the waiting list compared to a mere 8,000 annual donors, blockchain technology emerges as a beacon of innovation for the organ donation ecosystem. Originally the bedrock of cryptocurrencies like Bitcoin, blockchain has since traversed beyond the financial sector, exhibiting potential for securing medical records, authenticating pharmaceuticals, and mitigating fraudulent practices within healthcare. It presents a decentralized ledger that not only ensures data integrity and immutability but also fosters transparent and efficient donor-recipient matching through smart contracts. Despite the promising applications, the adoption of blockchain in healthcare confronts challenges including interoperability, data security, and regulatory hurdles. The present article encapsulates the transformative impact of blockchain, particularly within organ transplantation, and underscores the necessity for further research to surmount the barriers to its implementation. As blockchain technology continues to evolve, its capacity to reconcile the demand-supply disparity in organ donations is anticipated to save numerous lives, revolutionizing the healthcare landscape.
Optimizing Task Scheduling in Cloud Computing Environments using Hybrid Swarm Optimization
Authors: Kumar Niraj , Dugal Upasana , Singh Akanksha
Published: December 2023

Cloud computing has revolutionized the Information Technology (IT) landscape by offering on-demand access to a shared pool of computing resources over the internet. Effective task scheduling is pivotal in optimizing resource utilization and enhancing the overall performance of cloud systems. Tasks are allocated to virtual machines (VMs) based on a server's workload capacity, aiming to minimize traffic congestion and waiting times. Although Particle Swarm Optimization (PSO) is currently the most effective algorithm for task scheduling in cloud environments, this study introduces a Hybrid Swarm Optimization (HSO) algorithm that combines the strengths of PSO and Salp Swarm Optimization (SSO). The proposed hybrid algorithm addresses the challenges associated with task scheduling in cloud computing. The performance of the HSO algorithm is evaluated using the CloudSim simulator and compared against traditional scheduling algorithms. Simulation results indicate that the hybrid PSO-SSO algorithm outperforms existing methods regarding makespan time, cloud throughput, and task execution efficiency. Consequently, the hybrid approach significantly improves resource utilization and overall system performance in cloud computing environments.
Capital Convertibility: Empowerment Strategy For Micro-Entrepreneurs In Babelan Village, North Bekasi Regency
Authors: Wisesa Wimba , Lawang Robert M.Z
Published: December 2023

This study examines capital convertibility in Huripjaya Village, Babelan District, North Bekasi Regency. Capital convertibility refers to the ability of capital or economic resources to switch between forms or sectors to improve people's welfare. The main objective of this study is to analyze the dynamics of capital convertibility, the factors that influence it, and its impact on village development. The research method used is a combination of literature studies, field observations, and interviews with key stakeholders in Huripjaya Village. The results showed that the convertibility of capital in this village was influenced by internal and external factors, including geographical conditions, natural resources, institutions, and regional economic development. Factors such as economic diversification, the role of microfinance institutions, and community involvement in local decision-making play an important role in increasing capital convertibility. In addition, the existence of community economic training and education programs was also identified as a factor that contributed positively to economic structural changes in Huripjaya Village. In the context of development impacts, this study presents findings that increasing capital convertibility can make a significant contribution to improving the welfare of rural communities. This can be seen from the increase in population access to better health services, education, and infrastructure. This research provides valuable insights for policy makers, local governments, and other relevant parties to design more effective and sustainable development strategies at the village level.
Novas formações em carreiras técnicas
Authors: Oliveira José Palazzo Moreira de
Published: December 2023

Este artigo de proposição faz a defesa de um Ambiente Brasileiro de Educação mais flexível, com Sistema de Transferência e Acumulação de Créditos similar ao ECTS europeu, para promover a mobilidade estudantil e construção de conhecimentos e competências. Destaque para a importância de combinar formação técnica sólida com habilidades práticas e ênfase no empreendedorismo. Reconhecimento da necessidade de políticas de inclusão para enfrentar desigualdades. Enfatizo a relevância de uma formação adaptada às demandas do mercado de trabalho e ao dinamismo tecnológico. O objetivo é lançar o debate, trato o assunto em profundidade em outros artigos.
Jogos para Humanos e Robôs: Projetos Integrados baseados em Protótipos de Robôs em Cursos EAD
Authors: Silva Luís Rogério da , Gonçalves Eliane
Published: December 2023

Nesta pesquisa, analisamos os resultados relativos à participação online de estudantes universitários na execução de projetos no âmbito da construção de protótipos de robôs como atividade paralela aos componentes curriculares tradicionais. Limitamos esta pesquisa à análise do desempenho, em 2021, dos alunos da USAC – Universidade de São Carlos da Guatemala. Gerimos o processo de análise de desempenho dos protótipos apresentados por essas equipes através de uma plataforma online denominada RoboLeague.Com os dados referentes a essas participações no ano de 2021, formulamos uma investigação de natureza exploratória quantitativa e qualitativa. Os resultados mostraram o alcance desta iniciativa em termos didáticos.
The use of Padlet in activities of the Initial and Continuing Education Course in Computing, Technologies, and Educational Robotics for Basic Education in the EAD modality
Authors: Fausto Ilma Rodrigues de Souza , Leta Fabiana Rodrigues , Braz Ruth Maria Mariani , Silva Luemy Avila Santos , Almeida Edivânia Floro Nicácio
Published: December 2023

This research investigates the impacts of using Padlet in the teaching and learning process and explores its potential as a collaborative tool. Data collection was conducted through bibliometrics and content analysis, including scientific articles, theses, and related materials. The results have shown that the use of Padlet as a collaborative tool provides a conducive environment for content sharing, discussions, and collective knowledge construction. This approach stimulates interaction among educators and contributes to the development of collaborative and constructive activities.
Mulheres na Informática: Uma ação extensionista durante a pandemia da COVID 19
Authors: Santos José Bruno S. , Moura Karolinny O. F. , Souza Maria Vitória M. de , Neo Alana Viana Borges S. , Neo Giseldo S.
Published: December 2023

O presente trabalho tem por objetivo apresentar as atividades e experiências obtidas no Projeto Mulheres na Informática, ação extensionista vinculada ao Instituto Federal de Alagoas - Campus Palmeira dos Índios. O público-alvo dessa ação foram jovens garotas estudantes da rede pública de ensino da Escola Estadual Almeida Cavalcanti. O objetivo do projeto foi incluir as mulheres na área da computação através do ensino da informática. Como também, incentivar as participantes a terem em mente que a informática pode ser ocupada tanto por mulheres como por homens, de modo que elas pudessem desconstruir os rótulos impostos pela sociedade, e assim, considerarem a informática como uma carreira oportuna. Além de incluí-las digitalmente, proporcionando novas experiências e desenvolvendo habilidades na área da computação.
Uma Ferramenta Colaborativa para o Apoio do Ensino-Aprendizado do Português Escrito para a Diminuição da Desigualdade Educacional dos Surdos
Authors: Oliveira Efânio J. A. , Filadelfo Quézia M. , Freitas Daniela G. S. , Matos Pablo F.
Published: December 2023

O e-Sinais é um software educacional que realiza a tradução de português para sinais em LIBRAS com o objetivo de proporcionar aos surdos uma melhor experiência no aprendizado de novas palavras. Este artigo apresenta o desenvolvimento do e-Sinais em sua versão Web de forma colaborativa e responsiva com a adição de novas funcionalidades ao sistema, como a tradução de palavras sinônimas, homônimas e polissêmicas, e a gravação de sinais de forma colaborativa.
Design de Interação e os Estudos em Ciência, Tecnologia e Sociedade na formação docente continuada
Authors: Amaral Marilia Abrahão , Almeida Leonelo Dell Anhol , Aguiar Kelly Dayane , Feliciano Michelle Tais Faria , Gomes Henrique J. Polato , Machado Aline Alvares , Santos Michelle Regina Alves Dos
Published: December 2023

A formação docente dita continuada pode ser um caminho para o desenvolvimento profissional docente frente às novas propostas legislativas como a Base Nacional Comum Curricular. Este artigo tem como objetivo apresentar experiências de formação docente em tópicos que envolvem Design de Interação, sob a perspectiva dos estudos em Ciência, Tecnologia e Sociedade, com 340 docentes da Rede Municipal de Ensino de Curitiba nos anos de 2018, 2019, 2020 e 2022. Foram abordados conceitos de Design de Interação articulando-os com as competências Pensamento Computacional e Cultura Digital da BNCC, bem como conceitos de Ciência, Tecnologia e Sociedade. Este arcabouço é apresentado como resultado de tais experiências de formação.
Plataforma Metaverse Studio e Realidade Aumentada: aplicações ao contexto educacional
Authors: Santos Bruno P. C. dos , Leite Maici D. , Varela Paulo J.
Published: December 2023

O cenário escolar demanda instrumentos tecnológicos com potencial de enriquecer o aprendizado do aluno. Este artigo utiliza essa lacuna, para instigar o enriquecimento do ambiente de ensino, por meio de elementos virtuais. A plataforma abordada nesta pesquisa, possibilita o desenvolvimento de aplicações móveis de Realidade Aumentada, sem necessidade de programação. Assim, foi possível indicar que os recursos nativos ofertados pelo Metaverse Studio, oportuniza aos professores elaborar materiais instrucionais, por meio de aplicativos de Realidade Aumentada. Os resultados se mostraram satisfatórios para o período pós pandemia, dada a imersão e aplicação de Tecnologias da Informação e Comunicação (TIC) mais efetiva.
Abstrações reflexionantes e o meio digital: aliando recursos para a aprendizagem de conceitos de análise combinatória no Ensino Fundamental
Authors: Viganó Anelise P. Baur , Basso Marcus
Published: December 2023

Neste trabalho apresenta-se um experimento com 3 estudantes do Ensino Fundamental sobre a aprendizagem do conceito de combinação simples por meio de um recurso digital elaborado pela pesquisadora, em linguagem Scratch, no computador. Utilizaram-se questionamentos inspirados no Método Clínico de Piaget. A oficina foi gravada em vídeo e foram realizadas anotações pela pesquisadora em um diário de bordo. Estas informações foram analisadas sob a perspectiva da Abstração Reflexionante. Observou-se que a ferramenta criada possibilitou a presença da abstração pseudo-empírica e abstração reflexionante, o que pode evidenciar o potencial positivo para a aprendizagem de combinação.
Uso de RPG para auxiliar o ensino de Filosofia Antiga
Authors: Medeiros Lucas Vinicius Dantas de , Araújo Livia Celita Lopes , Silva Francisco Genivan
Published: December 2023

O projeto "RPG Filosofia Antiga" utilizou um RPG digital nomeado Filoilu para ensinar conceitos de filosofia antiga a alunos do ensino médio. O jogo foi baseado em conceitos filosóficos da Grécia Antiga e permitiu que os alunos se envolvessem em tomada de decisão baseada nos ensinamentos de filósofos como Platão e Aristóteles. O RPG foi implementado em um ambiente virtual, onde os alunos participavam de narrativas baseadas em questões filosóficas como ética, política e epistemologia. Os resultados mostraram que o RPG foi uma ferramenta eficaz para promover o engajamento e a aprendizagem dos alunos. Os participantes melhoraram sua compreensão dos conceitos filosóficos e sua capacidade de aplicá-los em situações da vida real.
Uso de Geradores de Imagens com Inteligência Artificial em Sala de Aula: Análise de Experiência do Usuário
Authors: Mezzomo Maristela Denise Moresco , Kawamoto André Luiz Satoshi , Wonsik Ester Cristiane
Published: December 2023

Este estudo analisou a Experiência do Usuário (UX) de um gerador de imagens baseado em Inteligência Artificial (IA). Os participantes foram alunos do ensino médio que utilizaram o Bing Image Creator durante atividades de Geografia em sala de aula. A avaliação de UX foi feita com o uso do UEQ-S. Os resultados mostraram uma experiência positiva com recursos satisfatórios e funcionalidades que atenderam às expectativas dos usuários. No contexto do processo de ensino-aprendizagem, as atividades com a ferramenta demonstraram o interesse dos alunos em tecnologias digitais e sua contribuição para a construção do conhecimento. Em resumo, este estudo destaca a importância de integrar ferramentas baseadas em IA na educação, enfatizando seu potencial impacto positivo na experiência do usuário e na aprendizagem.
Análise de Sentimentos e Emoções em Fóruns Educacionais: Um Estudo de Caso em um Curso de Formação Docente durante a Pandemia
Authors: Oliveira Eduardo Gomes de , Siqueira Sean Wolfgand Matsui , Classe Tadeu Moreira de , Bastos César Augusto Rangel
Published: December 2023

No contexto educacional, as emoções devem ser gerenciadas, pois afetam os processos cognitivos como a memorização e a tomada de decisão, apoiando a construção de conhecimento e o desenvolvimento de habilidades. Durante a pandemia de Covid-19, com o ensino remoto emergencial, muitos professores participaram de iniciativas de formação em tecnologias educacionais. Neste estudo, apresentamos uma análise das emoções e sentimentos de professores que participaram de um curso de formação docente. As análises feitas neste estudo de caso foram realizadas em fóruns educacionais do Ambiente Virtual de Aprendizagem (AVA) Moodle, utilizando a biblioteca Syuzhet da linguagem R. Como resultados, as emoções mais predominantes das mensagens dos fóruns foram confiança e antecipação. Em relação aos sentimentos, foram identificados mais sentimentos positivos do que negativos e neutros. Isto demonstra que, apesar dos desafios trazidos pelo período pandêmico, os professores percebiam os benefícios do uso de tecnologias para apoiar a Educação.
Tarefas exploratórias promotoras do Raciocínio Matemático: uma experiência com o uso de Ferramentas Tecnológicas na formação inicial de professores
Authors: Martins Márcio André , Meier Melissa
Published: December 2023

Através das orientações curriculares atuais, são recomendadas experiências de ensino visando à promoção do Raciocínio Matemático (RM). Neste estudo, foca-se na formação de futuros professores com vistas ao desenvolvimento do RM dos estudantes, mediado por Ferramentas Tecnológicas (FT). Esta é uma pesquisa de cunho qualitativo e interpretativo para investigar o planejamento de aulas centradas em tarefas exploratórias promotoras do RM, por futuros professores, com o uso de FT. A coleta de informações foi feita por meio de questionário, observação participante e produção escrita. A análise foi baseada nos princípios para elaboração de tarefas promotoras do RM. Os resultados apontam que os participantes desenvolveram novos conhecimentos em relação à temática abordada.
Exploring the impact of gamification and the Flippity tool in teaching Brazilian culture: insights and recommendations
Authors: Moreira Franciely Pereira , Lima Danielli Araújo
Published: December 2023

Gamification in education makes learning engaging, motivating, and interactive, stimulating active participation and skill development through game elements. In this context, this experiential report aims to describe and reflect on the use of games as an aid in the literacy process in the early years of elementary school, and how the use of the digital tool Flippity can contribute to this process. Besides that, we conducted a bibliographic analysis on the topic to enrich the reflection. The study reveals positive outcomes of using games in children’s literacy education, fostering enjoyable learning experiences. Based on these findings, we offer six recommendations to enhance gamification in literacy teaching to promote effective learning for students.
Robótica Educacional no Incentivo de Alunos do Primeiro Ano do Ensino Médio para Área de Computação: Um Relato de Experiência
Authors: Rodrigues Eunicio Gomes , Rodrigues Borrosa Matias , Silva Marinilson Ferreira da , Silva Rosenilde S. da , Libório Filho João da Mata
Published: December 2023

Este artigo apresenta um estudo com o objetivo de investigar como a abordagem pedagógica da Robótica Educacional pode despertar o interesse dos estudantes do primeiro ano do Ensino Médio e promover o aprendizado de forma dinâmica e interativa. O estudo foi conduzido em quatro fases progressivas, utilizando recursos como a plataforma Arduino e o modelo ESP32. Os resultados obtidos mostraram que a Robótica Educacional pode ser uma estratégia eficaz para incentivar os alunos a considerarem carreiras na área de Computação. Compreender esse impacto é fundamental para o desenvolvimento de estratégias de orientação vocacional efetivas.
Desenvolvimento do Pensamento Computacional por meio de atividades desplugadas no ensino de Gráficos de Funções Quadráticas
Authors: Valim João Cesar Maciel , Kaminski Márcia Regina , Boscarioli Clodis
Published: December 2023

O Desenvolvimento do Pensamento Computacional e suas habilidades têm sido considerado, cada vez mais, importante para a formação dos estudantes, e diante disso, emergem discussões sobre sua efetiva implementação nos diversos níveis da Educação e sua relação com os demais componentes curriculares. Nesse sentido, esse artigo traz formas – e reflexões sobre os resultados, de articular o ensino do conteúdo matemático de gráficos de funções quadráticas com o desenvolvimento das habilidades do Pensamento Computacional por meio de atividades desplugadas, desenvolvidas com alunos do 1° ano do Ensino Médio.