bluuebunny/crossref_metadata_2025 huggingface dataset:
Satisfaction With Telemedicine in Patients With Orthopedic Trauma During the COVID-19 Lockdown: Interview Study
Authors: Rauer Thomas , Scherer Julian , Stäubli Pascal , Gerber Jonas , Pape Hans-Christoph , Heining Sandro-Michael
Published: August 2022

Background

Telemedicine can take many forms, from telephone-only consultations to video consultations via a smartphone or personal computer, depending on the goals of the treatment. One of the advantages of videoconferencing is the direct visual contact between patients and therapists even over long distances. Although some telemedicine models require specially designed add-on devices, others get by with off-the-shelf equipment and software and achieve similarly successful successful results. This depends, among other things, on the nature of the injury, the desired outcome of therapy, and the medical consultation. In the last decade, the science and practice of telemedicine have grown exponentially and even more so during the COVID-19 pandemic. Depending on the traumatic lesion, posttraumatic and postoperative treatment and care of patients who experience trauma may require medical or physical therapy consultations in a clinic or office. However, due to the COVID-19 lockdown, direct physical follow-up was more difficult, and therefore, telemedicine solutions were sought and implemented.

Objective

The aim of this study was to assess satisfaction with telemedical aftercare in patients with orthopedic trauma.

Methods

Between March and July 2020, a standardized interview using a standardized questionnaire—Freiburg Index of Patient Satisfaction (FIPS)—among patients with orthopedic trauma who received telemedical postsurgical or physiotherapeutic care was conducted. The FIPS is composed of 5 questions regarding treatment and 1 question on the overall treatment satisfaction. Furthermore, we assessed patients’ demographics and their telemedical use. Subgroup analysis was performed for age groups (<65 years vs ≥65 years), the used device, and gender.

Results

In total, we assessed 25 patients with a mean age of 43 (SD 24.31) years (14 female). The majority of patients (n=19, 76%) used their smartphone for consultations. The mean overall FIPS score assessed was 2.14 (SD 0.87). The mean FIPS score for younger patients was 2.23 (SD 0.90) vs 1.91 (SD 0.82) for older patients. The vast majority of the surveyed patients (n=20, 80%) were absolutely confident with their smartphone or tablet use.

Conclusions

Most patients surveyed stated a high satisfaction with the telemedical follow-up. Older patients showed a higher satisfaction rate than their younger counterparts. It seems that telemedical postsurgical or physiotherapeutic care is a viable option, especially in times of reduced contact, like the current COVID-19 pandemic. Thus, telemedicine offers the opportunity to ensure access to effective patient care, even over long distances, while maintaining patient satisfaction.
Smartphone Apps for Surveillance of Gestational Diabetes: Scoping Review
Authors: Smyth Suzanne , Curtin Eimear , Tully Elizabeth , Molphy Zara , Breathnach Fionnuala
Published: August 2022

Background

Developments and evolutions in the information and communication technology sector have provided a solid foundation for the emergence of mobile health (mHealth) in recent years. The cornerstone to management of gestational diabetes mellitus (GDM) is the self-management of glycemic indices, dietary intake, and lifestyle adaptations. Given this, it is readily adaptable to incorporation of remote monitoring strategies involving mHealth solutions.

Objective

We sought to examine and assess the available smartphone apps which enable self-monitoring and remote surveillance of GDM with a particular emphasis on the generation of individualized patient feedback.

Methods

Five databases were searched systematically for any studies evaluating mHealth-supported smartphone solutions for GDM management from study inception until January 2022. The studies were screened and assessed for eligibility of inclusion by 2 independent reviewers. Ultimately, 17 studies were included involving 1871 patients across 11 different countries. The PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) conceptual framework was adhered to for data extraction and categorization purposes.

Results

All studies analyzed as part of this review facilitated direct uploading of data from the handheld glucometer to the downloaded patient-facing smartphone app. Glycemic data were captured by all studies and were reassuringly found to be either improved or noninferior to extant models of hospital-based care. Feedback was delivered in either an automated fashion through in-app communication from the health care team or facilitated through bidirectional communication with the app and hospital portal. Although resource utilization and cost-effective analyses were reported in some studies, the results were disparate and require more robust analysis. Where patient and staff satisfaction levels were evaluated, the response was overwhelmingly positive for mHealth smartphone–delivered care strategies. Emergency cesarean section rates were reduced; however, elective cesarean sections were comparatively increased among studies where the mode of delivery was assessed. Most reviewed studies did not identify any differences in maternal, perinatal, or neonatal health when app-based care was compared with usual in-person review.

Conclusions

This comprehensive scoping review highlights the feasibility, reliability, and acceptability of app-assisted health care for the management of GDM. Although further exploration of the economic benefit is required prior to implementation in a real-world clinical setting, the prospect of smartphone-assisted health care for GDM is hugely promising
The Effect of Classroom-Based Interventions on Sedentary Behavior and Spinal Health in Schoolchildren: Systematic Review
Authors: Fisher Dominic , Louw Quinette
Published: August 2022

Background

Multifaceted school-based interventions involving many stakeholders show promise toward the reduction of sedentary behavior (SB) and improved musculoskeletal conditions in schoolchildren. In resource-limited contexts, where schools face multiple, complex demands, broad school-based interventions may not be possible. In these settings, less complex, resource-efficient interventions are more likely to be adopted and implemented. Interventions that are limited to classrooms and that do not require broader stakeholder participation may be more appropriate to lower-resource settings.

Objective

The aim of this study was to systematically search for, identify, and summarize the literature on the effectiveness of classroom-based interventions on SB and spinal health in schoolchildren.

Methods

PubMed, EBSCOhost CINAHL, Web of Science, and Scopus were searched between January 1, 2021, and April 30, 2021. We included experimental studies conducted exclusively in school classrooms that objectively measured classroom SB and spinal health. The search terms related to SB, classroom sitting, and classroom neck and back pain. Studies that reported on objectively measured classroom physical activity and instrumented observation of healthy spinal behavior were included in the review. The included studies were critically appraised using the McMaster critical review form for quantitative studies. The study findings were summarized in tables, and a meta-analysis of homogeneous review outcome data was conducted.

Results

Overall, 12 experimental studies from high-income countries were included: 9 (75%) studies focused on SB, and 3 (25%) focused on spinal health. Of the 9 SB studies, 8 (89%) reported decreases in classroom sitting time. The pooled medium-term effects of a subset of SB interventions showed statistically significant decreases in sitting time (P=.03), whereas short-term effects and long-term effects were not significantly reduced (P=.13 and P=.23, respectively). A meta-analysis of spinal health studies demonstrated statistically significant improvements in spinal behavior during functional tasks (P=.005).

Conclusions

Classroom-based interventions aimed at reducing SB and improving spinal health may be effective without placing an additional burden on teachers and parents. SB interventions must include strategies to overcome teachers’ and learners’ hedonic motivation to sit during class time. Standardized outcomes for school-based SB are encouraged so that findings from various settings may be pooled to determine the overall effect across studies. The use of standardized functional outcomes in spinal health studies will aid in determining the effectiveness of spinal health interventions across studies.

Trial Registration

PROSPERO International Prospective Register of Systematic Reviews CRD42020176080; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020176080
Older Wheelchair Users Recommend Age-Friendly Design Improvements to a Wheelchair Maintenance App: Mixed Methods Development Study
Authors: Boccardi Alyssa , Wu Fangzheng , Pearlman Jon , Mhatre Anand
Published: August 2022

Background

Wheelchair part failures have doubled over the past decade. Preventative wheelchair maintenance reduces wheelchair failures and prevents user consequences. We are developing a smartphone app called WheelTrak, which alerts users when maintenance is required, to encourage maintenance practices and compliance.

Objective

This mixed methods study aimed to develop a wheelchair maintenance app using broad stakeholder advice and investigate older adults’ interaction experience with the app and their perceived barriers to and facilitators of maintenance.

Methods

Interviews were conducted with stakeholders, including mobility device users, to generate needs statements and app specifications. The app was designed in 2 stages. Stage 1 involved the development of the app according to the specifications and evaluation of the app interface by lead users. Stage 2 included the revision of the app screens and manual functionality testing. Usability testing and semistructured interviews were conducted with older wheelchair and scooter users. The System Usability Scale was used to measure app usability.

Results

Interviews with power and manual wheelchair users (37/57, 65%), wheelchair service providers (15/57, 26%), manufacturers (2/57, 4%), seating and mobility researchers (1/57, 2%), and insurance plan providers (2/57, 4%) informed the needs and specifications of the app technology. The 2-stage development process delivered a fully functional app that met the design specifications. In total, 12 older adults (mean age 74.2, SD 9.1 years; n=10, 83% women; and n=2, 17% men) participated in the usability testing study. Of the 12 participants, 9 (75%) agreed to use WheelTrak for preventative maintenance. WheelTrak scored an average System Usability Scale score of 60.25 (SD 16). Four overarching themes were identified: WheelTrak app improvements, barriers to maintenance, consequences related to mobility device failure, and smart technology use and acceptance. Older adults preferred the simplicity, readability, personalization, and availability of educational resources in the app. Barriers to maintenance pertained to health issues and lack of maintenance knowledge among older adults. Facilitators of maintenance included notification for maintenance, app connectivity with the service provider, reporting of device failure, and the presence of a caregiver for maintenance.

Conclusions

This study highlighted age-friendly design improvements to the app, making it easy to be used and adopted by older wheelchair users. The WheelTrak app has close to average system usability. Additional usability testing will be conducted following app revision in the future.
Technologies for Interoperable Internet of Medical Things Platforms to Manage Medical Emergencies in Home and Prehospital Care: Protocol for a Scoping Review
Authors: Seth Mattias , Jalo Hoor , Högstedt Åsa , Medin Otto , Björner Ulrica , Sjöqvist Bengt Arne , Candefjord Stefan
Published: August 2022

Background

Population growth and aging have highlighted the need for more effective home and prehospital care. Interconnected medical devices and applications, which comprise an infrastructure referred to as the Internet of Medical Things (IoMT), have enabled remote patient monitoring and can be important tools to cope with these demographic changes. However, developing IoMT platforms requires profound knowledge of clinical needs and challenges related to interoperability and how these can be managed with suitable technologies.

Objective

The purpose of this scoping review is to summarize the best practices and technologies to overcome interoperability concerns in IoMT platform development for medical emergencies in home and prehospital care.

Methods

This scoping review will be conducted in accordance with Arksey and O’Malley’s 5-stage framework and adhere to the PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols) guidelines. Only peer-reviewed articles published in English will be considered. The databases/web search engines that will be used are IEEE Xplore, PubMed, Scopus, Google Scholar, National Center for Biotechnology Information, SAGE Journals, and ScienceDirect. The search process for relevant literature will be divided into 4 different steps. This will ensure that a suitable approach is followed in terms of search terms, limitations, and eligibility criteria. Relevant articles that meet the inclusion criteria will be screened in 2 stages: abstract and title screening and full-text screening. To reduce selection bias, the screening process will be performed by 2 reviewers.

Results

The results of the preliminary search indicate that there is sufficient literature to form a good foundation for the scoping review. The search was performed in April 2022, and a total of 4579 articles were found. The main clinical focus is the prevention and management of falls, but other medical emergencies, such as heart disease and stroke, are also considered. Preliminary results show that little attention has been given to real-time IoMT platforms that can be deployed in real-world care settings. The final results are expected to be presented in a scoping review in 2023 and will be disseminated through scientific conference presentations, oral presentations, and publication in a peer-reviewed journal.

Conclusions

This scoping review will provide insights and recommendations regarding how interoperable real-time IoMT platforms can be developed to handle medical emergencies in home and prehospital care. The findings of this research could be used by researchers, clinicians, and implementation teams to facilitate future development and interdisciplinary discussions.

International Registered Report Identifier (IRRID)

DERR1-10.2196/40243
A Conceptual Framework (2D-ME) for Explaining Self–first and Self–third Person Views of Prototyping Dynamics in Serious Games Design: Experimental Case Study (Preprint)
Authors: Hadjileontiadou Sofia , Dias Sofia B , Hadjileontiadis Leontios
Published: August 2022

BACKGROUND

Design dynamics that evolve during a designer’s prototyping process encapsulate important insights about the way the designer is using his or her knowledge, creativity, and reflective thinking. Nevertheless, the capturing of such dynamics is not always an easy task, as they are built through alternations between the self–first and self–third person views.

OBJECTIVE

This study aimed at introducing a conceptual framework, namely 2D-ME, to provide an explainable domain that could express the dynamics across the design timeline during a prototyping process of serious games.

METHODS

Within the 2D-ME framework, the Technological-Pedagogical-Content Knowledge (TPACK), its adaptation to the serious games (TPACK-Game), and the activity theory frameworks were combined to produce dynamic constructs that incorporate self–first and self–third person extension of the TPACK-Game to Games TPACK, rules, division of labor, and object. The dynamic interplay between such constructs was used as an adaptation engine within an optimization prototype process, so each sequential version of the latter could converge to the designer’s initial idea of the serious game. Moreover, higher-order thinking is scaffolded with the internal Activity Interview Script proposed in this paper.

RESULTS

An experimental case study of the application of the 2D-ME conceptual framework in the design of a light reflection game was showcased, revealing all the designer’s dynamics, both from internal (via a diary) and external (via the prototype version) views. The findings of this case study exemplified the convergence of the prototyping process to an optimized output, by minimizing the mean square error between the conceptual (initial and updated) idea of the prototype, following explainable and tangible constructs within the 2D-ME framework.

CONCLUSIONS

The generic structure of the proposed 2D-ME framework allows its transferability to various levels of expertise in serious games mastering, and it is used both for the designer’s process exploration and training of the novice ones.
Implementation Science Perspectives on Implementing Telemedicine Interventions for Hypertension or Diabetes Management: Scoping Review (Preprint)
Authors: Khalid Ayisha , Dong Quanfang , Chuluunbaatar Enkhzaya , Haldane Victoria , Durrani Hammad , Wei Xiaolin
Published: August 2022

BACKGROUND

Hypertension and diabetes are becoming increasingly prevalent worldwide. Telemedicine is an accessible and cost-effective means of supporting hypertension and diabetes management, especially as the COVID-19 pandemic has accelerated the adoption of technological solutions for care. However, to date, no review has examined the contextual factors that influence the implementation of telemedicine interventions for hypertension or diabetes worldwide.

OBJECTIVE

We adopted a comprehensive implementation research perspective to synthesize the barriers to and facilitators of implementing telemedicine interventions for the management of hypertension, diabetes, or both.

METHODS

We performed a scoping review involving searches in Ovid MEDLINE, Embase, CINAHL, Cochrane Library, Web of Science, and Google Scholar to identify studies published in English from 2017 to 2022 describing barriers and facilitators related to the implementation of telemedicine interventions for hypertension and diabetes management. The coding and synthesis of barriers and facilitators were guided by the Consolidated Framework for Implementation Research.

RESULTS

Of the 17,687 records identified, 35 (0.2%) studies were included in our scoping review. We found that facilitators of and barriers to implementation were dispersed across the constructs of the Consolidated Framework for Implementation Research. Barriers related to cost, patient needs and resources (eg, lack of consideration of language needs, culture, and rural residency), and personal attributes of patients (eg, demographics and priorities) were the most common. Facilitators related to the design and packaging of the intervention (eg, user-friendliness), patient needs and resources (eg, personalized information that leveraged existing strengths), implementation climate (eg, intervention embedded into existing infrastructure), knowledge of and beliefs about the intervention (eg, convenience of telemedicine), and other personal attributes (eg, technical literacy) were the most common.

CONCLUSIONS

Our findings suggest that the successful implementation of telemedicine interventions for hypertension and diabetes requires comprehensive efforts at the planning, execution, engagement, and reflection and evaluation stages of intervention implementation to address challenges at the individual, interpersonal, organizational, and environmental levels.
Evaluating the Usability of Electronic Patient-Reported Outcome Apps: Comment on a Symptom Management Platform for Outpatients With Advanced Cancer (Preprint)
Authors: Haniuda Yu , Tsubaki Michihiro , Ito Yoshiyasu
Published: August 2022

UNSTRUCTURED
Uncovering the Reasons behind COVID-19 Vaccine Hesitancy in Serbia: Sentiment-Based Topic Modeling (Preprint)
Authors: Ljajić Adela , Prodanović Nikola , Medvecki Darija , Bašaragin Bojana , Mitrović Jelena
Published: August 2022

BACKGROUND

After the first COVID-19 vaccine appeared, there has been a growing tendency to determine public attitudes toward it automatically. In particular, it has been important to find the reasons for vaccine hesitancy, since it was directly correlated with pandemic protraction. Natural language processing (NLP) and public health researchers have turned to social media (Twitter, Reddit, and Facebook) for user-created content from which they could gauge public opinion on vaccination. To automatically process such content, they use a number of NLP techniques, most notably topic modeling. Topic modeling enables the automatic uncovering and grouping of hidden topics in the text. When applied to content that expresses negative sentiment toward vaccination, it can give a direct insight into reasons for vaccine hesitancy.

OBJECTIVE

This study applies NLP methods to classify vaccination-related tweets by sentiment polarity, and uncover reasons for vaccine hesitancy among the negative tweets in the Serbian language.

METHODS

To study the attitudes and beliefs behind vaccine hesitancy, we collected two batches of tweets that mention some aspects of the COVID-19 vaccination. 8,817 tweets were manually annotated as either relevant or irrelevant regarding the COVID-19 vaccination sentiment and then the relevant were annotated as positive, negative or neutral. We used the annotated tweets to train a sequential BERT-based classifier for two tweet classification tasks to augment this initial dataset. The first classifier distinguishes between relevant and irrelevant tweets. The second classifier used the relevant tweets and classified them as negative, positive or neutral. This sequential classifier was used to annotate the second batch of tweets. The combined datasets resulted in 3,286 tweets with a negative sentiment: 1,770 from the manually annotated dataset and 1,516 as a result of automatic classification. Topic modeling methods (LDA and NMF) were applied using 3,286 preprocessed tweets to detect reasons for vaccine hesitancy.

RESULTS

The relevance classifier achieves an F-score of 0.91 and 0.96 for relevant and irrelevant tweets, respectively. The sentiment polarity classifier achieves an F-score of 0.87, 0.85 and 0.85 for negative neutral and positive sentiment, respectively. By summarizing the topics obtained in both models, we extracted five main groups of reasons for vaccine hesitancy: Concern over vaccine side effects, Concern over vaccine effectiveness, Concern over insufficiently tested vaccines, Mistrust of authorities and Conspiracy theories.

CONCLUSIONS

This paper presents a combination of NLP methods applied to find the reasons for vaccine hesitancy in Serbia. Given these reasons, it is now possible to better understand the concerns of people regarding the vaccination process.
Nutritional Content in Snack Food: Consumer Perceptions and Behaviors
Authors: Amalia Rosa , Ismoyowati Dyah , Mulyati Guntarti Tatik
Published: August 2022

People's lifestyles encouraged them to devour the main dish in a short amount of time. It demonstrated the value of snack foods as a source of supplementary energy. To present an example of marketing agro-industry in some healthy snack foods for college student, it was necessary to understand consumer behaviors regarding sugar intake in snacking. The marketers need to understand the customer perceptions and behaviors towards nutritional content in snack foods to create healthy snack food. The aims of this study were: 1) to analyze the consumer perceptions and behaviors of nutritional content in snack food products; 2) to identify dominant factors which affect the consumption of snack food products. The study was conducted on 200 respondents of college students. Snack foods were commonly consumed by college students, who were classified as adolescents, in between substantial meals. Descriptive statistics and Principal Component Analysis (PCA) were performed. Consumer impressions on a preliminary assessment of the nutrition label, which includes sugar components, were determined using descriptive statistics. Furthermore, PCA was performed to identify the main consumer characteristics that affect snacking, allowing the impact of sugar content on snack food consumption. The results indicated that the consumers were concerned enough about eating nutritious meals. Consumers, on the other hand, rarely read nutrition labels. The "benefit" and "wants" factors were the most important elements affecting consumer snack food intake. The nutritious composition of snack foods, on the other hand, did not affect snack food consumption. The consumers were unconcerned about the sugar content in snack food.
The Implementation of Activity-Based Costing on Black Rice Supply Chain in Sleman District, Yogyakarta
Authors: Putriasih Anggriani Dwi , Ismoyowati Dyah , Suwondo Endy
Published: August 2022

As the primary rice consumers, Indonesians, especially people in Yogyakarta, particular consumers progressively changed their carbohydrate intake from white rice to black rice because of human health benefits. Consequently, from 2015 to 2018, Yogyakarta black rice farm extended its arable land, production, and productivity to fulfill the demand. The research aims to help the actor of business to supervise the activities, wasting higher costs and reducing the profit by analyzing the logistics cost structure along the black rice supply chain with Activity-Based Costing (ABC). The results found that the highest cost proportion of farmers (63.57%), farmer groups (69.97%), and distributors (50.47%) take place in the material handling activity. In comparison, retailers spend most of the cost on inventory activity (64.29%).
On Forms of Infringement and Protection of Short Video Advertising
Authors: Li YuTong
Published: August 2022

Short video advertising is a type of short video that can generate direct commercial benefits. Short video advertising wins out in terms of content, and its broadcast volume grows rapidly. Especially with the development of Internet economy, with well-known short video bloggers using platforms to sell products, advertisements are gradually the same as short videos and appear more and more on short video platforms. Short video advertising itself has the characteristics of marketing, coupled with the characteristics of its length, fast transmission, in the era of Internet fragmentation is widely used as a way of entertainment for the masses, a variety of resulting copyright issues will also trigger wider attention from all walks of life. This paper uses inductive analysis to analyze the marketing strategy and infringement risk of short video advertising, and makes clear the copyright protection system of short video advertising, and promote the healthy and orderly development of short video advertising industry.
Wavelength and Wave Period Relationship with Wave Amplitude: A Velocity Potential Formulation
Authors: Hutahaean Syawaluddin
Published: August 2022

In this study, the equation that expresses the explicit relationship between the wave number and wave amplitude, as well as wave period and wave amplitude are established. The wave number and the wave period are calculated solely using the input wave amplitude. The equation is formulated with the velocity potential of the solution to Laplace’s equation to the hydrodynamic conservation equations, such as the momentum equilibrium equation, Euler Equation for conservation of momentum, and by working on the kinematic bottom and free surface boundary condition.In this study, the equation that expresses the explicit relationship between the wave number and wave amplitude, as well as wave period and wave amplitude are established. The wave number and the wave period are calculated solely using the input wave amplitude. The equation is formulated with the velocity potential of the solution to Laplace’s equation to the hydrodynamic conservation equations, such as the momentum equilibrium equation, Euler Equation for conservation of momentum, and by working on the kinematic bottom and free surface boundary condition.
Zizwaf Digitalization: The Empowerment of People Economic’s Strategy Amidst Covid-19
Authors: Sari Nur Rahmah , Syariati Namla Elfa
Published: August 2022

This study aims to analyze the ability of Zakat Management Organizations to utilize technology in supporting transaction activities as well as reporting ZISWAF fund management as a strategy in increasing payments and distribution of ZISWAF funds. The object of this study is the National Amil Zakat Agency (BAZNAS) of Makassar, representing an institution established by the government, and Dompet Dhuafa of South Sulawesi, as one of the institutions established by the community. This study is a qualitative study using a case study approach. Data consist of primary data obtained by conducting direct interviews with informants, and secondary data obtained through observation of the website or application of each organization. This study found that in Dompet Dhuafa of South Sulawesi, the use of IT is maximized by trying to reach millennials, considering that they tend to be more receptive to the use of IT as they found it easy to use. Meanwhile, at BAZNAS of Makassar, the use of IT is maximized on their applications that comply with PSAK 109 concerning Zakat and Infaq/Alms Accounting, considering the muzakki in BAZNAS are mostly either eldery or government emlpoyees that really concern about the perceived of usefulness of the technology. As a case study, this study is expected to be able to contribute to other organization and the government by providing a comprehensive picture of what should be done in maximizing the use of IT as a strategy to increase the number of ZISWAF payments in Indonesia, in order to empower the people's economic, especially in the current era of the Covid-19 pandemic.
Perspectives on in silico bone mechanobio
Authors:   nstitute for Biomechanics, ETH Zurich, Leopold-Ruzicka-Weg 4, HCP H23.1, 8093 Zürich, Switzerland, Boaretti D , Wehrle E , Bansod YD , Tourolle né Betts DC , Müller R
Published: August 2022

Bone mechanobiology is the study of the physical, biological and mechanical processes that continuously affect the multiscale multicellular system of the bone from the organ to the molecular scale. Current knowledge derives from experimental studies, which are often limited to gathering qualitative data in a cross-sectional manner, up to a restricted number of time points. Moreover, the simultaneous collection of information about 3D bone microarchitecture, cell activity as well as protein distribution and level is still a challenge. In silico models can expand qualitative information with hypothetical quantitative systems, which allow quantification, testing and comparison to existing quantifiable experimental data. An overview of multiscale, multiphysics, agent-based and hybrid techniques and their applications to bone mechanobiology is provided in the present review. The study analysed how mechanical signals, cells and proteins can be modelled in silico to represent bone remodelling and adaptation. Hybrid modelling of bone mechanobiology could combine the methods used in multiscale, multiphysics and agent-based models into a single model, leading to a unified and comprehensive understanding of bone mechanobiology. Numerical simulations of in vivo multicellular systems aided in hypothesis testing of such in silico models. Recently, in silico trials have been used to illustrate the mechanobiology of cells and signalling pathways in clinical biopsies and animal bones, including the effects of drugs on single cells and signalling pathways up to the organ level. This improved understanding may lead to the identification of novel therapies for degenerative diseases such as osteoporosis.
Genotyping of Candida albicans and Comparison of its Antifungal Resistance Pattern in the South Indian Region
Authors: Kumar K.P. Prasanna , Tejashree A.
Published: August 2022

Recent studies have documented an increase in the incidence of antifungal resistance in newly emerging species closely related to C. albicans, and the coexistence of genotypic variants. Hence, an application of PCR-based molecular typing is crucial in identifying these fungi. Our study used molecular methods to characterize the latest genotypic subgroups of C. albicans and analysed if there was a relationship between the genotypes and the antifungal resistance pattern. The study was conducted in JSS Hospital, Mysuru, Karnataka between July 2018 and December 2020. A total of 1427 Candida species were isolated from clinical samples. Candida albicans were isolated and confirmed using Germ tube test, ID VITEK 2 and PCR (ITS primer). DNA extraction was done using the Hi-Media Yeast DNA Extraction Kit. The amplified products were analysed using Agarose gel electrophoresis (2%). Among 1427 Candida species, 282 were Candida albicans. The following resistance was exhibited to major antifungals – Caspofungin (3.5%), Amphotericin B (1.4%), flucytosine (2.8%) Fluconazole (6%) Micafungin (2.8%) Voriconazole (3.1%) and all were sensitive to miconazole. ABC genotyping showed Genotype A (450 bp) predominant (87.58%) followed by genotype B (840bp) (9.92 %) and genotype C (450bp and 840 bp) (0.2%). Genotype D and E were not observed. Our study showed the growing antifungal resistance in clinical isolates. Genotype A was predominant in South Karnataka region followed by Genotype B and C. There was no correlation between genotyping and antifungal resistance. However, a study with greater number of samples from diverse geographical locations may give more insight.
Gratitude training to improve quality of life for schizophrenic family caregivers
Authors: Rahmania Farra Anisa , Rumiani Rumiani
Published: August 2022

This study aims to determine the effect of gratitude training on the quality of life of schizophrenic family caregivers. The design in this study used two groups of pretest-post test with follow-up. The participants in this study were 10 schizophrenic family caregivers aged by 19-60 years. The number of participants in this study was 5 participants in the experimental group with 4 female participants and 1 male participant (M age = 41.2 years) and 5 participants in the control group with 4 female participants and 1 male participant (M age = 46.4 years). This study used the quality of life scale (WHOQOL-BREF) developed by the World Health Organization with Cronbach’s alpha reliability score of .828. The data analysis in this study used anava mixed. The results of the analysis showed that the research data was significant at p = .009 (p < .05) with a partial eta squared value of .553. The results showed that gratitude training 55.3% affected improving the quality of life of schizophrenic family caregivers. This intervention could be applied to increasing the family caregiver’s quality of life in the future.
Parental psychological control and cyberbullying tendency in adolescents from the perpetrator side
Authors: Rahmaputri Alifia Yuniar , Setiasih Setiasih , Kesumaningsari Ni Putu Adelia
Published: August 2022

This research aims to analyze the contributions of parents’ behavior to adolescent cyberbullying. It tests the role of parental psychological control and adolescent cyberbullying behaviour using a quantitative design with the selection of samples in the form of accidental sampling. Furthermore, the participants comprised 383 adolescents aged 13-17 years who live with both parents and have committed cyberbullying. The respondents filled out the questionnaires containing the Psychological Control – Disrespect Scale (PCDS) to measure the patent’s psychological control and  the Cyber-Aggression Scale (CYB-AGS). A multiple regression analysis showed that the control predicts adolescent cyberbullying behavior (R2= 0,053, F =10.619, p = 0.000), and as a predictor variable, it contributes 5.3% to cyberbullying behavior. According to the model, the father’s psychological control predicts adolescents’ cyberbullying behavior. This research reveals the significance of parental psychological control in adolescent cyberbullying behaviour.
Qualitative meta-analysis on the practice experience of pre-service early childhood teacher
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Jeong Ae
Published: August 2022

Objectives In this study, we intend to broaden our understanding of the practice experiences of pre-service early childhood teachers through a qualitative meta-analysis of the practice experiences of pre-service early childhood teachers and to investigate the future direction of practice for pre-service early childhood teacher. Methods This study analyzed the practice experiences of pre-service early childhood teacher through qualitative meta-analysis based on the qualitative meta-analysis execution process of Noblit and Hare (1988). Qualitative meta-analysis is largely divided into the first half and the second half. In the first half, research materials were collected and analysis subjects were selected, and in the second half, the results obtained by comparing and analyzing the selected research materials were categorized. Results As a result of comprehensively exploring the practice experiences of pre-service early childhood teacher, pre-service early childhood teacher experienced the practice process centered on ‘change in perception, practice of education, and enjoyment of relationships’. During the practice process, pre-service early childhood teacher experienced changes in their perception of young children, recognition of themselves as subjects in their surroundings, experience of practical knowledge, experience exhaustion, reflective thinking, interacting with teachers based on trust and support, and forming positive relationships with children through emotional enjoyment. Conclusions Based on the results of this study, we can consider emphasizing the active participation of young children and pre-service early childhood teacher, cultivating practical knowledge that combines theory and knowledge, promoting reflective thinking to coordinate the light and shade of practice, and forming a positive relationship with teachers and young children based on emotional support.
The Effect of Advanced Life Support Training on In-Hospital Cardiac Arrest Situations on Self-Leadership and Critical Thinking Disposition of Nursing Students
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Jang Kyeongmin , Kim Ju Ok , Hwang Hye Min
Published: August 2022

Objectives This study was conducted to confirm the effect of advanced life support (ALS) training for in-hospital cardiac arrest (IHCA) on self-leadership and critical thinking disposition of nursing students. Methods The study design was a quasi-experimental research design by a single group before and after, and the subjects of the study were a total of 57 students from a nursing department located in A city. The study period was January 2022. For the study subjects, a survey was conducted in advance, ALS training was conducted on cardiac arrest in the hospital, and a follow-up survey was conducted. Results As a result of this study, self-leadership (t=-7.39, p<.001) and critical thinking propensity (t=-8.82, p<001) showed a statistically significant increase after ALS training for IHCA situations compared to before training. Conclusions Through the results of this study, It was confirmed that ALS training for in-hospital cardiac arrest (IHCA) can improve self-leadership and critical thinking disposition. It will be possible to use as basic data to utilize teaching methods that can improve self-leadership and critical thinking disposition in the case of ALS training for IHCA situations.
A Study on Influence of Employee’s Exercise on Resilience, Mental Well-Being and Work Life Satisfaction
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Seo Jae-Hee , Huh Jung-Hoon
Published: August 2022

Objectives The purpose of this paper is to analyze the influence of employee’s exercise on resilience, mental well-being, and work life satisfaction and to verify the relationship between main variables. Methods This paper distributed and collected 465 surveys on subjects working as employees as of 2022 and used total of 440 surveys after removing the inadequate ones. SPSS 26.0, AMOS 26.0 for the frequency analysis, reliability analysis, exploratory factor analysis, confirmatory factor analysis, independent sample t test, ANOVA, correlation analysis, and multiple regression analysis. Results First, the employees showed significant difference in resilience, mental well-being, and work life satisfaction depending on gender, exercise participation, exercise frequency, and type of exercise. Secondly, the resilience showed a positive correlation with mental well-being’s psychological well-being, emotional well-being, and social well-being and work life satisfaction. In addition, mental well-being showed a positive correlation with work life satisfaction. Third, according to the multiple regression analysis results, the resilience had a significant influence on the mental well-being’s psychological well-being, emotional well-being, and social well-being and work life satisfaction. The emotional well-being and psychological well-being also had a significant influence on the work life satisfaction. Conclusions According the results, the employee’s exercise participation had a positive influence on the resilience, mental well-being, and work life satisfaction. The results also showed that exercise contributes on emotionally and psychologically stable state and higher work life satisfaction. Thus, there needs to be various motivational intervention strategies in individual and organizational level followed up by policy and institutional supports in governmental level to encourage the employees participate in exercise more actively.
Vaccination rates in Europe are not associated with online media intensity
Authors: Luís Catarina , Di Marzo Veronica Romina , Kaur Mandeep , Argyropoulos Christos , Devane Declan , Stewart Fiona Anne , Antoniou George , Hendrickx Greet , Hervius Askling Helena , Hellemans Margot , Cohen Miriam , Spivak Orly , Van Damme Pierre , Cox Rebecca Jane , Vene Sirkka , Sibia Sofie , Pana Zoi Dorothea , Olesen Ole , VACCELERATE Consortium on behalf of
Published: August 2022

To map the public information about COVID-19 vaccines and vaccine trials in Europe, we have compiled an inventory of online communication materials from official sources (e.g., governments, public agencies, and NGOs) via directed online research. While information for the general public was abundant across Europe, we found a large variation in number, type and target audiences among countries. Little or no information was found for population groups that are typically underrepresented in vaccine clinical trials. Materials about clinical trials and trial participation were also limited. Interestingly, higher number of media materials was not reflected in higher national vaccination rates.
Are Medical Students Adequately Trained to Care for Persons With Disabilities?
Authors: Marzolf Brianna A. , Plegue Melissa A. , Okanlami Oluwaferanmi , Meyer Daniel , Harper Diane M.
Published: August 2022

Background and Objectives: Insufficient provider training contributes to health care disparities for 61 million Americans with disabilities.2,4 This study examines medical students' perceptions of their disability training and the perceived effect training has on students' preparedness to care for people with disabilities (PWD) in future practice.
Methods: Principles of the Core Competencies on Disability for Health Care Education5 generated 10 questions. The questions were included in a survey conducted by the Council of Academic Family Medicine Educational Research Alliance (CERA) and sent to medical student members of the American Academy of Family Physicians (AAFP). We compared responses using unadjusted χ2 tests.
Results: One hundred forty-seven surveys were returned, with 126 used for this analysis; 36% of students reported that their medical training provided them with the knowledge necessary to provide high-quality, comprehensive health care for PWD in their future practice and 97.6% agreed or strongly agreed that they needed to learn more. Six of the curricular exposures demonstrating variations of the health care needs of PWD were associated with higher percentages of medical students agreeing they are trained to perform high-quality health care for PWD in future practice.
Conclusion: Medical students continue to report deficiencies in training, knowledge, and preparedness to care for PWD. Based on the Core Competencies framework, we have identified six curricular exposures that increase readiness to care for PWD. Therefore, we recommend the Liaison Committee on Medical Education formally integrate requirements for disability training in the standards of accreditation.7
Sintesis dan Karakterisasi Carbon Nanodots dengan Metode Microwave Assisted Extraction
Authors: Hulupi Mentik , Haryadi  , Nabila Sofiyani  , Rizka Amalia Nuriana  , Indarti Retno , Abdilah Fauzi
Published: August 2022

Carbon nanodots (CNDs) is one of the carbon nanoparticles that are environmentally friendly, non-toxic, and have optical properties. The aim of this study was to synthesize CNDs from ascorbic acid as a precursor using the Microwave Assisted Extraction method. method. Best results are obtained at 4 minutes of heating and 500W of power. The synthesized CNDs solution showed a blue color under 365 nm UV light. The measurement results with UV Vis spectrophotometer showed the maximum wavelength at 341.5 nm with an energy gap of 5.57 eV. The results of the Fourier transform infrared spectroscopy (FTIR) analysis show that CNDs have the -OH (hydroxyl) functional group at a wave number of 3354.61 cm-1 and C=O functional group at a wave number of 1633.09 cm-1. Characterization results using High resolution transmission electron microscopy (HRTEM) showed that CNDs were spherical in shape with a particle size range of 2.54-9.48 nm.
Pengaruh Penambahan Minyak Zaitun Terhadap Karakteristik dan Reologi Edible Film Berbahan Dasar Gluten
Authors: Djenar Nancy Siti , Suryadi Joko , Nursaadah Nisa Siti , Putri Erina
Published: August 2022

Gluten vegetable protein can be used as an alternative source of biopolymer as the basic material for edible film other than polysaccharides. Gluten-based edible films have a poor water vapor barrier and high cohesive and viscoelastic properties, therefore the addition of lipids and plasticizers is required. In this study, olive oil was added to reduce its permeability to water vapor, while glycerin was added to produce a more flexible edible film. The results showed that the addition of 1% olive oil could reduce the lowest water vapor transmission rate of 9.14 g/m2/24 hours with a thickness of 0.248 mm, tensile strength of 16.64 mPa, and elongation of 419.5%. The four characteristics are in accordance with the Japanese Industrial Standard. The antimicrobial testing on edible films showed that the addition of 0-2% olive oil could inhibit the growth of E. coli, while A. niger and R. oryzae 0-2% olive oil could not inhibit the growth of the two fungi. The measurement of optical properties showed that the transparency of the edible film was highest at the addition of 0% olive oil at 55%. The highest opacity value was with the addition of 1% olive oil, which is 2.96. The Fourier Transform Infrared (FTIR) identification showed that the edible film added with 1% olive oil had three characteristic absorption bands from gluten, olive oil, and an absorption band from glycerin. These bands indicate that olive oil, glycerin, and gluten do not react but only physically interact. The measurement using Scanning Electron Microscopy (SEM) and Energy Dispersive Spectrometer (EDS) showed that the microstructure of gluten-based edible film produces a varied structure where the gluten structure network can be clearly observed and contains elements of C, O, N where the intensity of C and O elements of 160-400 cps and 30-100 cps, respectively.