bluuebunny/crossref_metadata_2025 huggingface dataset:
Methodological approaches in 16S sequencing of female reproductive tract in fertility patients: a review
Authors: Davidson I. M. , Nikbakht E. , Haupt L. M. , Ashton K. J. , Dunn P. J.
Published: October 2024

Background

The female genital tract microbiome has become a particular area of interest in improving assisted reproductive technology (ART) outcomes with the emergence of next-generation sequencing (NGS) technology. However, NGS assessment of microbiomes currently lacks uniformity and poses significant challenges for accurate and precise bacterial population representation.

Objective

As multiple NGS platforms and assays have been developed in recent years for microbiome investigation—including the advent of long-read sequencing technologies—this work aimed to identify current trends and practices undertaken in female genital tract microbiome investigations.

Results

Areas like sample collection and transport, DNA extraction, 16S amplification vs. metagenomics, NGS library preparation, and bioinformatic analysis demonstrated a detrimental lack of uniformity. The lack of uniformity present is a significant limitation characterised by gap discrepancies in generation and interpretation of results. Minimal consistency was observed in primer design, DNA extraction techniques, sample transport, and bioinformatic analyses.

Conclusion

With third-generation sequencing technology highlighted as a promising tool in microbiota-based research via full-length 16S rRNA sequencing, there is a desperate need for future studies to investigate and optimise methodological approaches of the genital tract microbiome to ensure better uniformity of methods and results interpretation to improve clinical impact.

Graphical Abstract
Isolated Calmness of Perturbation Mappings and Superlinear Convergence of Newton-Type Methods
Authors: Benko Matúš , Mehlitz Patrick
Published: October 2024

In this paper, we characterize Lipschitzian properties of different multiplier-free and multiplier-dependent perturbation mappings associated with the stationarity system of a so-called generalized nonlinear program popularized by Rockafellar. Special emphasis is put on the investigation of the isolated calmness property at and around a point. The latter is decisive for the locally fast convergence of the so-called semismooth* Newton-type method by Gfrerer and Outrata. Our central result is the characterization of the isolated calmness at a point of a multiplier-free perturbation mapping via a combination of an explicit condition and a rather mild assumption, automatically satisfied e.g. for standard nonlinear programs. Isolated calmness around a point is characterized analogously by a combination of two stronger conditions. These findings are then related to so-called criticality of Lagrange multipliers, as introduced by Izmailov and extended to generalized nonlinear programming by Mordukhovich and Sarabi. We derive a new sufficient condition (a characterization for some problem classes) of nonexistence of critical multipliers, which has been also used in the literature as an assumption to guarantee local fast convergence of Newton-, SQP-, or multiplier-penalty-type methods. The obtained insights about critical multipliers seem to complement the vast literature on the topic.
Application of time series and multivariate statistical models for water quality assessment and pollution source apportionment in an Urban River, New Jersey, USA
Authors: Soetan Oluwafemi , Nie Jing , Polius Krishna , Feng Huan
Published: October 2024

Water quality monitoring reveals changing trends in the environmental condition of aquatic systems, elucidates the prevailing factors impacting a water body, and facilitates science-backed policymaking. A 2020 hiatus in water quality data tracking in the Lower Passaic River (LPR), New Jersey, has created a 5-year information gap. To gain insight into the LPR water quality status during this lag period and ahead, water quality indices computed with 16-year historical data available for 12 physical, chemical, nutrient, and microbiological parameters were used to predict water quality between 2020 and 2025 using seasonal autoregressive moving average (ARIMA) models. Average water quality ranged from good to very poor (34 ≤ µWQI ≤ 95), with noticeable spatial and seasonal variations detected in the historical and predicted data. Pollution source tracking with the positive matrix factorization (PMF) model yielded significant R2 values (0.9 < R2 ≤ 1) for the input parameters and revealed four major LPR pollution factors, i.e., combined sewer systems, surface runoff, tide-influenced sediment resuspension, and industrial wastewater with pollution contribution rates of 23–30.2% in the upstream and downstream study areas. Significant correlation of toxic metals, nutrients, and sewage indicators suggest similarities in their sources.

Graphical Abstract
Marketing inputs and outcome heterogeneity: Using a quantile regression framework in the entertainment industry
Authors: Burmester Alexa B. , Clement Michel , Becker Jan U. , Otten Cord
Published: October 2024

The success of entertainment products such as movies or books varies tremendously, and managers strive to increase the odds by deciding on the right marketing input. Aiming to improve managerial decision making, we suggest and test a quantile regression framework to detect outcome heterogeneity effects of marketing inputs in the entertainment industry. By analyzing the spread of the .9 and the .1 conditioned quantile to the .5 (median) conditioned quantile, we study how much an increase (decrease) of an input factor (star power and quality) changes the spread of the expected outcome (revenues and sales). The spread serves as an indicator for the heterogeneity effect of the input factor regarding the outcome. In two empirical studies, we show how marketing instruments increase (or decrease) outcome heterogeneity by estimating quantile regressions and provide generalizable findings regarding the outcome heterogeneity effects of star power (increases outcome heterogeneity) and quality evaluations (reduces outcome heterogeneity) in the entertainment industry.
Pseudomonas koreensis AB36 from a gold mine: genomic insights into adaptation to extreme conditions and potential plant growth promotion
Authors: Ayangbenro Ayansina Segun , Olanrewaju Oluwaseyi Samuel , Amoo Adenike Eunice , Babalola Olubukola Oluranti
Published: October 2024

The genus Pseudomonas is one of the most varied and widespread bacterial genera, with species found in most environment. They are known to degrade organic and inorganic compounds, produce secondary metabolites, and enhance plant growth. The genome of Pseudomonas koreensis AB36, a heavy metal resistant organism isolated from a gold mine was sequenced to unveil the versatile metabolic potential of the organism. The genome is a single circular chromosome of 5,902,614 bp, with G + C content of 60.1%. There are 4154 similar orthologous gene clusters shared among strain AB36 and other sequenced P. koreensis strains with 7 clusters found alone in the genome of strain AB36. Genome mining of the organism predicted 8 biosynthetic gene clusters using antiSMASH including three non-ribosomal peptide synthethase (NRPS) clusters, arylpolyene and bacteriocin. The genome contains putative genes for heavy metal transport/resistance. These results show the heavy metal resistance ability and degradation of xenobiotic compounds of strain AB36 as well as its potential to adapt to various environments.
“We Need to Not Fear You”: Essential Factors Identified by Sworn Officers and Civilian Staff for Implementation and Expansion of a Co-Response Program
Authors: Plassmeyer Mark , Gute Melissa , Stauss Kim
Published: October 2024

The Fayetteville, AR, Police Department (FPD) initiated a co-response program in 2021, partnering with social workers to respond to individuals in crisis. Originally started with a University of Arkansas School of Social Work (UA) internship, the Crisis Intervention Response Team (CIRT) has grown over time. The program now includes two full-time co-response teams, two social work interns, and plans for further expansion. UA provides support for the program through continued internships, clinical supervision, and program evaluation. This article reports on one aspect of the UA program evaluation focusing on FPD employees’ perspectives on integrating social workers into their department and how those perspectives have changed over time as the program has expanded. Through semi-structured interviews and survey data collected in 2021 and 2023, this research highlights key factors contributing to the program’s successes and continued challenges. The results provide valuable insights, suggestions, and other factors to consider for similar police departments when making decisions whether to establish or expand co-response initiatives.
An Integrative Pause for Healthcare Personnel Challenged by the War: A Personal Perspective
Authors: Kassem Sameer , Gressel Orit
Published: October 2024

Background

As the war in the Middle East intensifies, the support and well-being of healthcare practitioners (HCPs) become paramount to sustaining an effective healthcare system capable of serving the diverse Israeli population.

Methods

In collaboration with the integrative medicine (IM) team, we initiated a treatment intervention with the goal to relieve war-related HCPs concerns.

Results

This trilogy of narratives highlights the multifaceted experiences of HCPs in Israel during times of conflict. The director of internal medicine ward with his conventional medical and leadership expertise, provides stability and order. The IM practitioner offers holistic healing and care. The nurse reflects on her experience of being cared for.

Conclusions

These narratives illustrate the adaptability and resilience of healthcare professionals who navigate their roles with dedication and compassion, ensuring that amidst the strife, the human spirit remains cared for and supported.
Comparing functional countability and exponential separability
Authors: Hernández-Gutiérrez Rodrigo , Spadaro Santi
Published: October 2024

A space is functionally countable if every real-valued continuous function has countable image. A stronger property recently defined by Tkachuk is exponential separability. We start by studying these properties in GO spaces, where we extend results by Tkachuk and Wilson, and prove a conjecture by Dow. We also study some subspaces of products that are functionally countable and the influence of the

$$G_\delta $$

G
δ

-topology on exponential separability. Finally, we give some examples of functionally countable spaces that are separable and uncountable.
D’Arcy Thompson and Synthetic Biology—Then and Now
Authors: Davies Jamie A.
Published: October 2024

Though often presented as a recent scientific endeavor, synthetic biology began in the 19th century and was a particularly active field in the years preceding the publication of D’Arcy Thompson’s On Growth and Form. Much synthetic biology of the era was devoted to the construction of nonliving chemical systems that would undergo morphogenesis or dynamic behaviors which had been observed in living organisms. The point was to show that “life-like” structure and behavior could be generated by physicochemical laws and required no vitalist element. D’Arcy Thompson’s careful analysis of physicochemical morphogenetic mechanisms as possible explanations of organic form links closely to this way of thinking. In the modern era, when we can genetically engineer cells to undergo specific behaviors, and program cells to undergo simple morphogenetic behaviors of the kind that Thompson and others felt might underly natural morphogenesis, it is possible to test whether they will in fact produce a predictable multicellular shape. This addresses essentially the same questions about the morphogenetic role of physicochemical forces, such as surface tension, but does so “the other way round”: physicochemical mechanisms are not being used as models for morphogenesis by natural cells but rather as a means to engineer cells to make designed forms.
Biological Theories of Morphogenesis Based on Holistic Biophysical Thinking
Authors: Palmquist Karl H. , Ko Clint S. , Shyer Amy E. , Rodrigues Alan R.
Published: October 2024

The roles played by physics in the study of the life sciences have taken many forms over the past 100 years. Here we analyze how physics can be brought to bear on the contemporary study of morphogenesis, where new tissue-scale forms arise out of simpler, more homogenous, initial structures. We characterize how morphogenesis has been studied through reductionist approaches and discuss their limitations. We suggest that an alternative way of approaching morphogenesis that begins with a consideration of the whole may also serve as a fruitful mode of scientific inquiry. Through historical analysis of concepts relevant for contemporary systems biology, we illustrate how physical thinking oriented toward the biological whole (“holistic biophysical thinking”) was exemplified in the biological theories presented earlier by D’Arcy Thompson (1860–1948) and Pere Alberch (1954–1998). We contrast the use of physics to develop the conceptual foundations of holistically oriented systems biology with the more prevalent contemporary use of physics that focuses on technological development and quantification, embedded within reductionist strategies. As an in-depth contemporary case study, we describe how in our research we have used holistic biophysical thinking to develop biological theories of vertebrate morphogenesis that account for and extend beyond genetic, molecular, and cellular processes. We propose a theory of skin development where both molecular and morphological patterns are orchestrated by emergent physical processes at the supracellular scale. We further posit that holistic biophysical thinking at the supracellular scale may advance theories of diseases such as cancer.
Localization of underground pipeline intrusion sources using cross-correlation CNN: application in pile-driving model test
Authors: Chai Fu , Zhou Biao , Xie Xiongyao , Zhang Zixin , Han Jianyong
Published: October 2024

Preserving the structural integrity of critical infrastructure systems necessitates a heightened focus on fortifying the protection of underground pipelines. To this end, this paper presents an innovative approach, namely the Multi-Sample Joint Localization Method (MSJLM) utilizing Cross-Correlation Convolutional Neural Networks (CC-CNN), aimed at precisely localizing intrusion sources in the vicinity of underground pipelines. Traditional techniques for detecting and pinpointing pipeline intrusions primarily rely on a single sensor monitoring point, which is susceptible to inherent errors and constraints. In contrast, the MSJLM proposed in this study leverages data from multiple samples, integrating diverse data sources through correlation analyses to elevate precision and reliability. The utilization of the CC-CNN framework for processing aggregated data has proven highly successful in extracting spatial features and identifying patterns. Furthermore, the effectiveness of this method is corroborated through validation via a pile-driving model test.
Effect of laser drilling process on combustor liner effusion hole quality
Authors: Tas K. , Ozogul H. , Sever K. , Cin B.
Published: October 2024

Effusion cooling is one of the significant cooling technologies in combustor liners in terms of cooling efficiency and weight reduction. However, effusion cooling technology is difficult to manufacture. In fact this technology requires laser-drilling of thousands of tiny holes with shallow angles on a sheet metal with a thickness generally varying between 0.5 to 1.5 mm. In addition, the use of thermal barrier coating is common in gas turbine engines and is one more challenge for the drilling process. In order to obtain more efficient gas turbine engines, the inlet temperature keeps increasing in the last decades, which induces the combustion chamber to operate in a hotter environment. Therefore, efficient cooling technology is needed, even if it is hard to manufacture. For laser drilling, several parameters have to be explored to obtain acceptable holes. This study includes the microstructure investigations of the holes produced with different laser parameters and the optimal laser parameters determined according to the microstructure of six different effusion cooling hole configurations. The results show that laser process differences affect the metal substrate microstructure and thermal barrier coating structure. Drilling method, peak power, number of pulses, gas type and pressure value have a significant effect on the hole geometry and its microstructure.
The Relationality of Community Development Agreements towards a Human Rights Due Diligence Good Faith Requirement
Authors: Ogunranti Akinwumi
Published: October 2024

Human rights due diligence (HRDD) is a buzzword in business and human rights (BHR) activities. However, multinational corporations (MNCs) often conduct it as a tick-box exercise without transparency. Using a relational contract theory, this article argues that when MNCs contract with local communities through community development agreements (CDAs) to perform HRDD, such contracts are internationalized relational contracts that attract a level of good faith. An established principle in international economic law, good faith serves as a standard for assessing conduct designed to discharge obligations in international contracts between states and MNCs (investor-state contracts). Similar to how investor-state arbitration tribunals use good faith jurisprudence in regulating the relationship between states and MNCs, this article proposes a BHR good faith jurisprudence to prescribe how HRDD obligations should be discharged. The article concludes that a good faith interpretational exercise in BHR would (1) reduce MNCs’ cosmetic compliance with HRDD principles; (2) increase transparency in the HRDD exercise; and (3) become a source of rights for local communities to enforce corporate accountability.
Arctic Governance in the Face of Climate Change: A Case for “Inclusive Regionalism”
Authors: Dyck Carol
Published: October 2024

Arctic governance has entered a period of turmoil following the March 2022 Arctic Council pause in operations and, subsequently, the strained relations between the member states. As climate change dramatically alters the Arctic environment, opening the region to new economic possibilities and more global attention, the need for cooperation is greater than ever. This article examines the current geopolitical and environmental pressures that are undermining the Arctic Council’s legitimacy and operations at a critical juncture in Arctic governance. It contends that the Arctic Council must rethink how it engages with Arctic Council observers and the wider global community to ensure that pressing ecological, economic, and social issues are addressed judiciously to prevent potentially irreparable harm in the region. Specifically, the case is made that a shift to “inclusive regionalism” could secure the Arctic Council’s position as the pre-eminent forum to address Arctic issues and to re-establish the spirit of collaboration that reigned for a quarter century.
A mathematical theory of super-resolution and two-point resolution
Authors: Liu Ping , Ammari Habib
Published: October 2024

This paper focuses on the fundamental aspects of super-resolution, particularly addressing the stability of super-resolution and the estimation of two-point resolution. Our first major contribution is the introduction of two location-amplitude identities that characterize the relationships between locations and amplitudes of true and recovered sources in the one-dimensional super-resolution problem. These identities facilitate direct derivations of the super-resolution capabilities for recovering the number, location, and amplitude of sources, significantly advancing existing estimations to levels of practical relevance. As a natural extension, we establish the stability of a specific

$l_{0}$

minimization algorithm in the super-resolution problem.

The second crucial contribution of this paper is the theoretical proof of a two-point resolution limit in multi-dimensional spaces. The resolution limit is expressed as

$$\begin{align*}\mathscr R = \frac{4\arcsin \left(\left(\frac{\sigma}{m_{\min}}\right)^{\frac{1}{2}} \right)}{\Omega} \end{align*}$$

for

${\frac {\sigma }{m_{\min }}}{\leqslant }{\frac {1}{2}}$

, where

${\frac {\sigma }{m_{\min }}}$

represents the inverse of the signal-to-noise ratio (

${\mathrm {SNR}}$

) and

$\Omega $

is the cutoff frequency. It also demonstrates that for resolving two point sources, the resolution can exceed the Rayleigh limit

${\frac {\pi }{\Omega }}$

when the signal-to-noise ratio (SNR) exceeds

$2$

. Moreover, we find a tractable algorithm that achieves the resolution

${\mathscr {R}}$

when distinguishing two sources.
Limiting regimes of turbulent horizontal convection. Part 1. Intermediate and low Prandtl numbers
Authors: Passaggia Pierre-Yves , Scotti Alberto
Published: October 2024

We report the existence of two new limiting turbulent regimes in horizontal convection (HC) using direct numerical simulations at intermediate to low Prandtl numbers. In our simulations, the flow is driven by a step-wise buoyancy profile imposed at the surface, with free-slip, no-flux conditions along all other boundaries, except along the spanwise direction, where periodicity is assumed. The flow is shown to transition to turbulence in the plume and the core, modifying the rate of heat and momentum transport. These transitions set a sequence of scaling laws that combine theoretical arguments from Shishkina, Grossmann and Lohse (SGL) and Hughes, Griffiths, Mullarney and Peterson (HGMP). The parameter range extends through Rayleigh numbers in the range [

$6.4\times 10^5, 1.92\times 10^{15}$

] and Prandtl numbers in the range [

$2\times 10^{-3},2$

]. At low Prandtl numbers and intermediate Rayleigh numbers, a core-driven regime is shown to follow a Nusselt-number scaling with

$Ra^{1/6}Pr^{7/24}$

. For Rayleigh numbers larger than

$10^{14}$

, the Nusselt number scales with

$Ra^{0.225}Pr^{0.417}$

. For these particular regimes, the Reynolds number is found to scale as

$Ra^{2/5}Pr^{-3/5}$

for the low-Prandtl-number regime and

$Ra^{1/3}Pr^{1}$

for Rayleigh numbers larger than

$10^{14}$

. These results embed the HGMP model in the SGL theory and extend the known regime diagram of HC at high Rayleigh numbers. In particular, we show that HC and Rayleigh–Bénard share similar turbulent characteristics at low Prandtl numbers, where HC is shown to be ruled by its core dynamics and turbulent boundary layers. This new scenario confirms that fully turbulent HC enhances the transport of heat and momentum with respect to previously reported regimes at high Rayleigh numbers. This work provides new insights into the applicability of HC for geophysical flows such as overturning circulations found in the atmosphere, the oceans, and flows near the Earth's inner core.
Limiting regimes of turbulent horizontal convection. Part 2. Large Prandtl numbers
Authors: Passaggia Pierre-Yves , Cohen Nadia F. , Scotti Alberto
Published: October 2024

Horizontal convection at large Rayleigh and Prandtl numbers is studied experimentally in a regime up to seven orders of magnitude larger in terms of Rayleigh numbers than previously achieved. To reach Rayleigh numbers up to

$10^{17}$

, the horizontal density gradient is generated using differential solutal convection by a differential input of salt and fresh water controlled by diffusion in a novel experiment in which the zero-net mass flux of water is ensured through permeable membranes. This set-up allows us to accurately measure the Nusselt number in solutal convection by carefully controlling the amount of salt water exchanged through the membranes. Combined measurements of density and velocity across more than five orders of magnitude in Rayleigh numbers show that the flow transitions from the Beardsley & Festa (J. Phys. Oceanogr., vol. 2, issue 4, 1972, pp. 444–455), Shishkina & Wagner (Phys. Rev. Lett., vol. 116, issue 2, 2016, 024302) regime to the Chiu-Webster et al. (J. Fluid Mech., vol. 611, 2008, pp. 395–426) regime and frames the present results within the scope of Shishkina et al. (Geophys. Res. Lett., vol. 43, issue 3, 2016, pp. 1219–1225), and the theory of Part 1 (Passaggia & Scotti, vol. 997, 2024, J. Fluid Mech., A5). In particular, we show that, even for large Prandtl numbers, the circulation eventually clusters underneath the forcing horizontal boundary, leaving a stratified core without motion. Finally, the previous regime diagrams (Hughes & Griffiths, Annu. Rev. Fluid Mech., vol. 40, 2008, pp. 185–208; Shishkina et al., Geophys. Res. Lett., vol. 43, issue 3, 2016, pp. 1219–1225) are extended by combining the present results at high Prandtl numbers, the results at low Prandtl numbers of Part 1, together with previous results from the literature. This work sets a new picture of the transition landscape of horizontal convection over six orders of magnitude in Prandtl number and sixteen orders of magnitude in Rayleigh number.
Enablers of successful employment outcomes for people with disabilities
Authors: Ikutegbe Paul , Randle Melanie , Sheridan Lynnaire , Gordon Robert , Allingham Samuel , Connolly Alanna , Dolnicar Sara
Published: October 2024

Successful employment outcomes are often beyond the reach of people with disabilities, but relatively little is known about the factors that best enable the achievement of this goal. Using survey data from 803 people with and without disabilities, we examine the association of eight factors with successful employment outcomes. Using regression tree analysis, five factors emerged as statistically significant predictors of successful employment outcomes for people with disabilities: corporate culture and climate, job characteristics, government support, employer attitudes, and societal attitudes. Key interrelationships between factors include: (1) government support linking with corporate culture and climate; and (2) job characteristics linking with corporate culture and climate. Findings are relevant to organisations and governments to inform policy and practice to improve employment outcomes for people with disabilities.
Theoretical stability of ice shelf basal crevasses with a vertical temperature profile
Authors: Coffey Niall Bennet , Lai Ching-Yao , Wang Yongji , Buck W. Roger , Surawy-Stepney Trystan , Hogg Anna Elizabeth
Published: October 2024

Basal crevasses threaten the stability of ice shelves through the potential to form rifts and calve icebergs. Furthermore, it is important to determine the dependence of crevasse stability on temperature due to large vertical temperature variations on ice shelves. In this work, considering the vertical temperature profile through ice viscosity, we compare (1) the theoretical crack depths and (2) the threshold stress causing the transition from basal crevasses to full thickness fractures in several fracture theories. In the Zero Stress approximation, the depth-integrated force at the crevassed and non-crevassed location are unbalanced, violating the volume-integrated Stokes equation. By incorporating a Horizontal Force Balance (HFB) argument, recent work showed analytically that the threshold stress for rift initiation is only half of that predicted by the Zero Stress approximation. We generalize the HFB theory to show that while the temperature profile influences crack depths, the threshold rifting stress is insensitive to temperature. We compare with observations and find that HFB best matches observed rifts. Using HFB instead of Zero Stress for cracks in an ice-sheet model would substantially enlarge the predicted fracture depth, reduce the threshold rifting stress and potentially increase the projected rate of ice shelf mass loss.
Investigating the dynamic history of a promontory ice rise using radar data
Authors: Ershadi M. Reza , Drews Reinhard , Tison Jean-Louis , Martín Carlos , Henry A. Clara J. , Oraschewski Falk Marius , Tsibulskaya Veronica , Sun Sainan , Wauthy Sarah , Koch Inka , Bons Paul Dirk , Eisen Olaf , Pattyn Frank
Published: October 2024

Ice rises hold valuable records revealing the ice dynamics and climatic history of Antarctic coastal areas from the Last Glacial Maximum to today. This history is often reconstructed from isochrone radar stratigraphy and simulations focusing on Raymond arch evolution beneath the divides. However, this relies on complex ice-flow models where many parameters are unconstrained by observations. Our study explores quad-polarimetric, phase-coherent radar data to enhance understanding near ice divides and domes, using Hammarryggen Ice Rise (HIR) as a case study. Analysing a 5 km profile intersecting the dome, we derive vertical strain rates and ice-fabric properties. These align with ice core data near the summit, increasing confidence in tracing signatures from the dome to the flanks. The Raymond effect is evident, correlating with surface strain rates and radar stratigraphy. Stability is inferred over millennia for the saddle connecting HIR to the mainland, but dome ice-fabric appears relatively young compared to 2D model predictions. In a broader context, quad-polarimetric measurements provide valuable insights into ice-flow models, particularly for anisotropic rheology. Including quad-polarimetric data advances our ability to reconstruct past ice flow dynamics and climatic history in ice rises.
The Boundaries of Twenty-first-Century Policing
Authors: Gordon Daanika
Published: October 2024

Three new books by sociologists—The Policing Machine by Tony Cheng, The Minneapolis Reckoning by Michelle Phelps, and The Danger Imperative by Michael Sierra-Arévalo—offer us a view into the state of US policing leading up to and following the racial reckoning of 2020. I read these books together through the lens of boundary work, examining what they tell us about the various projects that seek to maintain, expand, or change police jurisdiction over the production of public safety. Collectively, these books suggest that the police work to preserve and extend their extant role and power. Meanwhile, boundary work through movement mobilization and political systems has aimed to contain policing through law and policy, shrink policing within municipal service systems, and replace policing through community-led models of safety. These projects point us toward important areas of inquiry in efforts to understand whether and how policing can change.
The Sacraments of Initiation as ‘Proof of Concept’ for Bernard Lonergan’s ‘Four-Point Hypothesis’
Authors: Schlesinger Eugene R.
Published: October 2024

This essay endeavors a correlation between Bernard Lonergan’s ‘four-point hypothesis’ – a theological proposal integrating trinitarian theology and the supernatural order of ‘created grace’ – and the sacraments of initiation. The same formal structure that Lonergan discerned in the experience of grace, itself a means of participation in the life of the Trinity, is replicated in the sacramental reception of that grace in those ritual acts whereby one is made a Christian. This at once serves as a ‘proof of concept’, lending credence to the Lonerganian proposal, and provides a speculative framework for understanding how it is that the sacraments introduce Christians into the divine life.
Opinion dynamics beyond social influence
Authors: Meylahn Benedikt V , Searle Christa
Published: October 2024

We present an opinion dynamics model framework discarding two common assumptions in the literature: (a) that there is direct influence between beliefs of neighboring agents, and (b) that agent belief is static in the absence of social influence. Agents in our framework learn from random experiences which possibly reinforce their belief. Agents determine whether they switch opinions by comparing their belief to a threshold. Subsequently, influence of an alter on an ego is not direct incorporation of the alter’s belief into the ego’s but by adjusting the ego’s decision-making criteria. We provide an instance from the framework in which social influence between agents generalizes majority rules updating. We conduct a sensitivity analysis as well as a pair of experiments concerning heterogeneous population parameters. We conclude that the framework is capable of producing consensus, polarization and fragmentation with only assimilative forces between agents which typically, in other models, lead exclusively to consensus.
Effect of the Mediterranean diet on the faecal long-chain fatty acid composition and intestinal barrier integrity: an exploratory analysis of the randomised controlled LIBRE trial
Authors: Seethaler Benjamin , Basrai Maryam , Neyrinck Audrey M. , Vetter Walter , Delzenne Nathalie M. , Kiechle Marion , Bischoff Stephan C.
Published: October 2024

We recently showed that adherence to the Mediterranean diet increased the proportion of plasma n-3 PUFA, which was associated with an improved intestinal barrier integrity. In the present exploratory analysis, we assessed faecal fatty acids in the same cohort, aiming to investigate possible associations with intestinal barrier integrity. Women from the Lifestyle Intervention Study in Women with Hereditary Breast and Ovarian Cancer (LIBRE) randomised controlled trial, characterised by an impaired intestinal barrier integrity, followed either a Mediterranean diet (intervention group, n 33) or a standard diet (control group, n 35). At baseline (BL), month 3 (V1) and month 12 (V2), plasma lipopolysaccharide-binding protein, faecal zonulin and faecal fatty acids were measured. In the intervention group, faecal proportions of palmitoleic acid (16:1, n-7) and arachidonic acid (20:4, n-6) decreased, while the proportion of linoleic acid (18:2, n-6) and α linoleic acid (18:3, n-3) increased (BL-V1 and BL-V2, all P < 0·08). In the control group, faecal proportions of palmitic acid and arachidic acid increased, while the proportion of linoleic acid decreased (BL-V1, all P < 0·05). The decrease in the proportion of palmitoleic acid correlated with the decrease in plasma lipopolysaccharide-binding protein (ΔV1-BL r = 0·72, P < 0·001; ΔV2-BL r = 0·39, P < 0·05) and correlated inversely with adherence to the Mediterranean diet (Mediterranean diet score; ΔV1-BL r = –0·42, P = 0·03; ΔV2-BL r = -0·53, P = 0·005) in the intervention group. Our data show that adherence to the Mediterranean diet induces distinct changes in the faecal fatty acid composition. Furthermore, our data indicate that the faecal proportion of palmitoleic acid, but not faecal n-3 PUFA, is associated with intestinal barrier integrity in the intervention group.
Gender, Intersectionality, and Global Social History
Authors: Wiesner-Hanks Merry E.
Published: October 2024

One of the most fruitful concepts of recent social analysis has been that of intersectionality, the idea that the nature of oppression is multiplicative rather than additive, and that no one identity – race, class, gender, religion, ability, sexual orientation, and so on – should be considered apart from other identities, but is always materialized in terms of and by means of them. Although it was developed out of the US experience, intersectional epistemology has been dynamic and mobile, as scholars have not simply used social groupings drawn from the Western past and present but have elaborated social categories taken from local understandings as well. This article analyses some recent examples of gendered world history that also take other social hierarchies into account, and assesses how these help us better understand global processes that transformed societies. It begins with a place and time where global entanglements led quite clearly to the emergence of new social groups, the Spanish and Portuguese colonies in the Americas, and then more briefly examines this process in other parts of the early modern colonial world.
Mercantile Elites and the Making of Global Capitalism
Authors: Dejung Christof
Published: October 2024

Global trade is a topic that is well suited for conceptualizing global social history as it allows the opportunity to challenge the notion that global markets were primarily congruent with imperial territories. Businessmen were regularly able to establish economic networks that transgressed state borders and challenged imperial aims for territorial control. This may be evidence for the fact that capitalism and imperialism were two different, although sometimes converging, spatial structures, each with a distinct logic of its own. Even in the colonial period, and despite the prevalence of imperial racism, co-operation between metropolitan capitalists and businessmen from peripheries was possible – and, in fact, the rule rather than the exception. This co-operation was facilitated by similar business practices and a similar mercantile culture, which is why the two constituencies have been described as joint members of a globally connected bourgeoisie in several studies. The ability of economic elites to establish transregional business structures is highly relevant for conceiving global social history as a distinct approach. It reveals that the activities of these actors were crucial for establishing global capitalism, and allows scholars to examine the embeddedness of mercantile elites in their socio-economic environment and in particular to study the relation between capital and labour.
Rationalising surgical instruments in tonsillectomy: a pilot study to reduce greenhouse gas emissions and costs
Authors: Yeo Justin Jui Yuan , Gupta Keshav Kumar , Mughal Zahir , Bhatt Chaitanya
Published: October 2024

Objective

The healthcare industry is estimated to contribute 4.4 per cent of global greenhouse gas emissions. This pilot study aimed to investigate the impact of rationalising surgical instruments in tonsillectomy trays on greenhouse gas emissions and costs.

Method

We conducted a prospective observational study over a six-month period. All patients who underwent tonsillectomy were included. The instruments used during the procedure and their frequency of use were counted, with the operating surgeon being unaware of the study.

Results

During the 6-month timeframe, 46 tonsillectomies were performed. From the standard tonsillectomy tray containing 38 pieces, 9 pieces were never used. The removal of unused reusable instruments resulted in an estimated total reduction of 594 g of carbon dioxide equivalents and a saving of €9.63 per operation.

Conclusion

Rationalising the contents of the surgical instrument tray can have a positive environmental impact by reducing greenhouse gas emissions. There are also pecuniary benefits for the National Health Service because of the potential for cost savings.
Does the scutum of the external auditory canal have a role in the stapedotomy operation? A radio-clinical evaluation
Authors: Elzayat Saad , El-Shirbeny Hussein A , Barbara Maurizio , Covelli Edoardo , Elsheikh Mohamed Nasser , Salem Mohammed Abdelbadie , Ebeed Ahmed I , Elfarargy Haitham H
Published: October 2024

Objective

This study aimed to assess the impact of the scutum on oval window accessibility during stapedotomy surgery. Radio-clinical correlation was applied to determine the impact.

Methods

This was a prospective observational case-series study that included 127 candidates for stapedotomy surgery. The oval fossa was classified into two types according to the accessibility of the stapes footplate.

Results

Both study groups showed a statistically significant difference in pre-operative radiological length as the p value was less than 0.001. The Spearman correlation coefficient revealed that the intra-operative oval window fossa was only significantly related to the radiological scutum length because the p value was less than 0.001.

Conclusion

Our results revealed that the pre-operative radiological length can predict the intra-operative oval fossa type with high sensitivity and specificity. Patients with a pre-operative scutum length of less than 2.35 mm were predicted to have an easily accessible oval window without requiring intra-operative scutum curettage.
Revisiting the retroauricular revolving door island flap: Our experience
Authors: Mora Sánchez Carolina , Oishi Natsuki , Campos Catalá Agustín , Zapater Latorre Enrique
Published: October 2024

Objectives

Surgical treatment of auricular concha, the helix root and the external auditory canal tumours, and their reconstruction, is a challenge because of the complexity of this anatomic region and the significant functional and aesthetic requirements of these treatments. The purpose of this study is to describe our experience with the retroauricular revolving door island flap technique.

Method

This was a retrospective descriptive study (series of nine clinical cases) conducted between 2020 and 2023 of revolving door island flap reconstruction of auricular conchal and external auditory canal defects caused by tumour removal.

Results

In all the cases, tumour-free margins and total reconstruction of the defect were achieved through the revolving door island flap intervention, with optimal aesthetic and functional results.

Conclusion

Revolving door island flap reconstruction is a viable surgical option for the reconstruction of auricular conchal and external auditory canal defects because of its versatility, reproducibility, low post-operative morbidity and optimal results.
High carnivore richness despite human pressure and prey depletion in the south-west of the Kavango–Zambezi Transfrontier Conservation Area
Authors: Verschueren Stijn , Hofmann Tim , Kakove Mikael , Bauer Hans , Cristescu Bogdan , Marker Laurie
Published: October 2024

Transfrontier conservation landscapes, such as the Kavango–Zambezi Transfrontier Conservation Area (KAZA TCA) in southern Africa, play a crucial role in preserving global biodiversity and promoting the sustainable development of local communities. However, resources to facilitate management could become scarce across large areas, leading to difficulties in obtaining baseline ecological information. Consequently, in the absence of sustainable management vast landscapes may experience loss of wildlife species, which could destabilize ecosystems. This effect is particularly significant if the loss involves top predators. Hence, understanding carnivore distributions is critical to informing management. We conducted a mammal survey in the Ondjou Conservancy in Namibia, an 8,729 km2 understudied area in the south-west of the KAZA TCA. We analysed camera-trapping data from a 2,304 km2 grid and identified high carnivore richness (18 species) despite widespread human activity and prey depletion. Using a multi-species occupancy framework we found that carnivore occurrence increased with increasing distance from the main village and with closer proximity to the Nyae Nyae Conservancy neighbouring the KAZA TCA, which has large and diverse carnivore populations. Carnivore occurrence was higher when local prey richness was high. The Ondjou Conservancy could function as an important buffer for the larger conservation network, yet rural communities in this area require support for fostering human–wildlife coexistence. Additionally, restoring the natural prey base will be critical to ensuring the long-term viability of carnivore populations in this and other human-impacted landscapes. With many remote areas of transfrontier conservation landscapes being understudied, our findings illustrate the conservation potential of such areas within large-scale conservation networks.
Cultural and socio-demographic drivers shape seahorse uses in Malaysia: implications for conservation
Authors: Ng Reana May Yen , Then Amy Yee-Hui , Lim Adam Chee Ooi
Published: October 2024

Seahorses Hippocampus spp. are commercially and culturally important to many communities. Although seahorses are widely used in traditional medicine, as curios and as aquarium fishes in Southeast Asia, documentation on the current nature and extent of culturally motivated seahorse uses in Malaysia is lacking. To examine how ethnicity and other socio-demographic drivers shape traditional medicinal use and underlying cultural beliefs involving seahorses, we administered a questionnaire-based survey during March 2021–April 2022 to members of the general public and fishers in Malaysia. Approximately one-fifth (21.0%) of respondents reported consuming seahorses (34.4% of these used seahorses for medicinal purposes, 55.2% for other non-medicinal uses and 10.4% for both types). Consumers of seahorses were from all ethnic groups except for Indigenous groups. In the general public group, medicinal use was more common amongst the Chinese respondents, whereas in the fisher group, other uses were more common amongst the Malay respondents. Amongst the threats facing seahorses, which include overfishing, habitat destruction, bycatch and ocean plastic pollution, only bycatch was perceived as a major threat by most of the general public and fisher respondents. The relatively low prevalence of reported seahorse use amongst Malaysians is an encouraging finding from a conservation perspective. However, the high proportion of non-medicinal uses indicates the need to focus on such other uses to ensure the sustainability of seahorse use in Malaysia.
Location and timing of infection drives a sex-bias in Haemoproteus prevalence in a hole-nesting bird
Authors: Jones William , Menon P. Navaneeth Krishna , Qvarnström Anna
Published: October 2024

Sex biases in prevalence of disease are often attributed to intrinsic factors, such as physiological differences while a proximate role of extrinsic factors such as behavioural or ecological differences may be more difficult to establish. We combined large-scale screening for the presence and lineage identity of avian malaria (haemosporidian) parasites, in 1234 collared flycatchers (Ficedula albicollis) with life-history information from each bird to establish the location and timing of infection. We found an overall infection rate of 36.2% ± 0.03 (95% CI) with 25 distinct malaria lineages. Interestingly, first-year breeding males and females had similar infection prevalence while females accrued a significantly higher infection rate than males later in life. The sex difference in infection rate was driven by the most abundant Haemoproteus, lineage, hPHSIB1, while the infection rate of Plasmodium lineages was similar in males and females. Furthermore, when infections were assigned to an apparent transmission location, we found that the sex difference in infection rate trend was driven by lineages transmitted in Europe, more specifically by one lineage (the hPHSIB1), while no similar pattern was found in African lineages. We deduce that the observed infection patterns are likely to be caused by differences in breeding behaviour, with incubating females (and nestling individuals of both sexes) being easy targets for the biting insects that are the vectors of avian malaria parasites. Overall, our results are most consistent with ecological factors rather than intrinsic factors underlying the observed sex-biased infection rate of avian malaria in collared flycatchers.