bluuebunny/crossref_metadata_2025 huggingface dataset:
Learning Mathematics from Home During Covid-19: A Study from the Perspective and Challenges of Grade 1-3 Learners as Basis for Designing “Learn Math-At-Home” Program
Authors: TORIBIO SHERYVIE L. , MONZALES FRENCRIS JOY S. , AMIGO ANCHE S.
Published: March 2023

This study was conducted to identify the level of engagement in learning mathematics during covid-19 and the challenges encountered among Grade 1-3 learners to design an intervention program.Quan-Qual method of research design was used to complete this action research specifically, sequential explanatory design. The study involved eighteen (18) learners research participants. Specifically, six (6) in each Grade level in 1, 2 and 3 using stratified sampling. The target respondents undergone one on one interaction through home visitation to gather the needed data through an interview. Then, documentary analysis was used based on the results for the development of the said target output. The study found out that learners’ challenges encountered in learning mathematics were lack of understanding and guidance.This study implies that the teacher and school must be innovative and resourceful enough and ensure the quality delivery of learning to learners.
Developing a Compression-moulded Composite Partitioning Panel from Banana Fibres and PLA
Authors: Weerasinghe Dakshitha , Hedigalla Dilshan , Dassanayaka Dumindu , Wanasekara Nandula , Gunasekera Ujithe , Mohotti Damith
Published: March 2023

Green construction materials developed using renewable resources have become the focus of concurrent research owing to increasing environmental considerations and legislations. However, most of the available literature focus only on load-bearing construction elements. Consequently, little attention has been paid towards non-load-bearing construction elements such as partitioning materials. The present work aims to address this gap by investigating the viability of using the biodegradable bioplastic PLA in combination with yarns spun using banana fibres to manufacture a composite panel intended for temporary partitioning materials used in the construction industry. Pre-tensioned banana yarns were used as the reinforcement while PLA was used as the matrix. The composite panels were manufactured using the compression moulding technique. The effect of process parameters such as moulding temperature and pressure, the effects of the degree of pre-tension and the amount of reinforcing yarn on the performance of the panels were investigated. The optimum moulding conditions were found to be 180oC moulding temperature and 15 tonnes of moulding pressure. Yarn pre-tensioning exhibited a positive effect on the performance of the composite panels. However, increasing the reinforcing yarn percentage caused a degradation of flexural performance of the composite. Finally, the performance was compared against the most widely used partitioning material currently, medium-density fibreboard (MDF). The novel composite panel manufactured at optimum conditions exhibited 52% higher impact strength and 55% higher flexural strength when compared to MDF. The composite panel presented herein has the potential to replace MDF as a better performing material manufactured using renewable resources.
Ensino de Programação Paralela na Educação Básica: Uma Revisão Sistemática da Literatura, Análise Bibliométrica e Agenda para Estudos Futuros
Authors: Perez Felipe Pereira , Oliveira Wilk , Lima Anderson Corrêa de , Castro Junior Amaury Antônio de , Araújo Graziela
Published: March 2023

Na última década, especialmente devido ao aumento do poder computacional, e, por conseguinte a urgência da programação paralela, surgiu a necessidade de profissionais capacitados para desenvolver softwares que utilizam todo o potencial paralelo das máquinas. Com isso, o ensino de programação paralela, por muito tempo exclusivo dos cursos de graduação, abriu espaço para ser trabalhado também na Educação Básica. No entanto, antes de começar a propor abordagens especificas para o ensino de programação paralela na Educação Básica, é necessário entender o estado da arte nesse domínio. Para enfrentar esse desafio, foi conduzida uma Revisão Sistemática da Literatura com o objetivo de i) identificar quais abordagens têm sido empregadas no ensino de programação paralela na Educação Básica; ii) detectar quais linguagens de programação são utilizadas; iii) levantar quais conceitos são abordados; iv) apontar em quais fases de ensino são aplicadas essas abordagens; e v) identificar como tem sido a experiência dos estudantes na aprendizagem. Como resultado, é possíve identificar que i) o número de publicações ainda é limitado; ii) a maioria dos estudos são conduzidos em oficinas de curta duração; iii) a maioria dos estudos são conduzidos apenas nos Estados Unidos da América; iv) a maioria dos estudos usa abordagens tradicionais de ensino; v) não há consenso em relação ao uso de linguagens de programação no ensino de programação paralela; vi) a maioria dos estudos foram conduzidos no Ensino Médio; e vii) em geral, a experiencia dos estudantes foi positiva. Os resultados contribuem especialmente para a área de Educação em Computação, abrindo espaço para o desenvolvimento de novas abordagens para o ensino de programação paralela.
Ensino, Aprendizagem e Uso Profissional da UML em Belo Horizonte e Região
Authors: Guelman Ian , OliveiraJr Edson , Xavier Laerte
Published: March 2023

A modelagem representa uma parte essencial do processo de desenvolvimento de um software, para tal, destaca-se a Linguagem de Modelagem Unificada (UML, do inglês Unified Modeling Language). Existem estudos que mostram como tem sido sua utilização na indústria de software, porém pouco se sabe em relação a seu ensino e aprendizado. Assim, este artigo busca entender não só como ocorre a utilização da UML por profissionais, mas também como ocorreu o aprendizado dos mesmos e como é realizado o ensino pelos docentes em Belo Horizonte e região. Para tal, foi realizada a replicação de um estudo conduzido originalmente na cidade de Maringá (PR). Foram aplicados dois surveys, um para 13 docentes e outro para 33 profissionais, com intuito de captar suas observações sobre o ensino, aprendizado e utilização da UML na região de Belo Horizonte. Os resultados obtidos podem auxiliar o ensino de UML, aproximando-o do contexto e das práticas adotadas na indústria.
Uma Ferramenta para Auxiliar o Desenvolvimento do Pensamento Computacional em Crianças
Authors: Santos Arthur , Oliveira Felipe , Campos Glaucia
Published: March 2023

O Pensamento Computacional (PC) tem sido aplicado como uma estratégia para a resolução de problemas por meio dos conceitos da Computação. Na educação, a aplicação do PC representa uma forma de disseminar informações e produzir conhecimento. É possível encontrar na literatura diferentes soluções que aplicam esse conceito. Porém, cada solução deve considerar fatores como o nível de escolaridade, o conteúdo abordado e o sistema de ensino (público/privado) devido aos custos gerados. Este trabalho apresenta o processo de modelagem/simulação de uma ferramenta (brinquedo de programar), baseada em Arduino, com a finalidade de auxiliar a aplicação das concepções do PC na Educação Infantil. Para comprovar o seu funcionamento correto, a arquitetura da ferramenta foi implementada nos simuladores Proteus e Tinkercad e foram realizadas várias simulações. Espera-se que a ferramenta possa ser construída e implementada, futuramente, em escolas carentes de recursos e soluções com esse propósito.
Passar nos casos de teste é suficiente? Identificação e análise de problemas de compreensão em códigos corretos
Authors: Silva Eryck Pedro da , Caceffo Ricardo Edgard , Azevedo Rodolfo
Published: March 2023

O uso de sistemas de correção automática (autograders) auxilia o ensino de disciplinas de introdução à programação (CS1). No entanto, o foco na corretude pode ofuscar a verificação de outros problemas presentes no código. Neste trabalho, foi investigado se códigos, ditos corretos por um autograder, apresentavam comportamentos que poderiam indicar falhas na aprendizagem dos conceitos abordados em CS1. Esses comportamentos foram denominados Problemas de Compreensão em Códigos Corretos (PC³). Ao analisar 2441 códigos, uma lista com 45 PC³ foi elaborada e posteriormente avaliada por docentes de CS1 para identificar quais PC³ mais necessitam de correção em sala de aula e de que forma essa correção poderia ser realizada. Ao todo, 15 PC³ foram considerados mais graves e as sugestões dos docentes envolveram detecção automática dos PC³ e utilização de técnicas de Aprendizagem Ativa. Os resultados obtidos podem orientar a construção de artefatos para intervenções que abordem PC³ em CS1.
Die Verantwortung der Europäischen Union in der Welt – eine deutsch-nordisch-baltische Perspektive
Authors: Dinkel Serafine
Published: March 2023

Russia's attack on Ukraine in February 2022 has led to a reorganisation of the European security architecture, which is particularly evident in the North and Baltic Sea regions. Europe reacted to the aggression in a united manner and faced up to its geopolitical and humanitarian responsibilities. The European Union (EU) and its member states made a remarkable turnaround in security policy and abandoned hitherto irrevocable principles regarding arms exports and neutrality. Yet the question of how best to manage the direct and indirect costs of the war divides EU member states. Moreover, the persistent challenges posed by matters as diverse as industrial, migration and asylum policy, foreign policy towards China and the climate crisis, have not gone away. The EU must leverage its power so that these can be mastered jointly and proactively.
„Trade Enforcement Regulation“, „Anti-Coercion Instrument“ und „Single Market Emergency Instrument“: Reaktionen der Europäischen Union auf handelspolitische Herausforderungen
Authors: Hummer Waldemar
Published: March 2023

In recent years, there has been an increasing number of examples of foreign countries seeking to influence the decisions of the European Union (EU) or its member states in the area of trade and investment policy. Unfortunately, the existing EU legislative framework does not provide for a single or comprehensive legal instrument to deter and counteract coercive actions by third countries. With this in mind, the European Commission recently adopted three proposals to impose counter-measures: The “Trade Enforcement Regulation” (TER), the “Anti-Coercion Instrument” (ACI) and the “Single Market Emergency Instrument” (SMEI). This article summarizes key points, development, contribution, and criticism of the three instruments through which the EU can defend itself against economic coercion by third countries, establish a resilient internal market and prove her strategic autonomy.
Vermögensverwaltung in der Betreuung
Authors: Wittke Andrea
Published: March 2023

Rechts- und Handlungssicherheit gewinnen Das an praktischen Fragestellungen orientierte Handbuch soll veranschaulichen, wie Vermögensverwaltung und Vermögensanlage gesetzeskonform – nach dem neuen Betreuungsrecht 2023 – zu gestalten sind. Behandelt werden der Erwerb von Vermögenswerten und mögliche Verfügungen darüber unter Abhandlung vieler Einzelgeschäfte. Vorteile und Risiken werden dargestellt. Die Darlegung möglicher Fehlverhalten soll verhindern, dass der Betreuer Schadensersatzansprüchen ausgesetzt sein könnte. Beispiele und Tipps erleichtern die Umsetzung in die praktische Arbeit. Das Praxishandbuch Vermögensverwaltung in der Betreuung vermittelt damit das notwendige Fachwissen und ist bestens geeignet, wenn dem in der Betreuung Tätigen ein entsprechender Aufgabenbereich im Aufgabenkreis zugewiesen wurde. Auch dem Rechtspfleger des Betreuungsgerichts dient das Handbuch als wertvolle Grundlage zur Überwachung der Vermögensverwaltung. </p
Digital services development in Ukraine
Authors: Petkun Svetlana , Kravchenko Milena , Yaroshovets Tetiana , Kulinich Oleg
Published: March 2023

Digital technologies, electronic communications, and digital services are currently being intensively developed in all spheres of Ukrainian society. Digitalization of public services at the state level helps to meet the expectations and needs of citizens in real time and contributes to improving the quality and sustainability of the services provided. At the same time, despite the progress made in the digitalization of public services, the proper functioning of the digital state is being hampered by a significant number of citizens who, for objective or subjective reasons, cannot use digital services. In other words, there is a digital divide, which determines the strengthening of the inclusiveness of the provision of digital services based on the principles of non-discrimination, taking into account the diversity of people, effective involvement and inclusion of all its participants in the digital process to improve the quality of life and well-being.
Information Security of the State Under Conditions of Hybrid Warfare: Mechanisms of Ensuring
Authors: Ablazov Ivan , Harkavyi Yevhenii , Mokliak Sergii , Rubel Karina , Smolianiuk Volodymyr
Published: March 2023

Taking into account the tendencies of democratization and informatization of all sectors of the economy and spheres of public administration, and, accordingly, the increase in information risks, the vast majority of countries in the world today go through a series of stages of ensuring information security. Despite the legislatively established powers of the relevant state authorities and local self-government in this area, the issues of defining their competence and effective interaction are real and effective guarantees of preventing a variety of information threats to national security as in this case effective and timely ways of eliminating existing dangers are provided. Given that large-scale invasions and hybrid wars can cause catastrophic harm and undermine public confidence in the government, the state must make quick decisions. Consequently, establishing an effective mechanism for ensuring information security has become more relevant than ever nowadays. The purpose of the academic paper is to clarify the theoretical fundamentals, as well as the components, directions and other critical practical aspects of the process of ensuring the state’s information security under conditions of hybrid warfare. Methodology. In the course of the research, abstraction, idealization, system-structural, comparative, logical-linguistic methods, analysis, synthesis, induction, deduction were used to process scientific information on issues of the state’s information security. Results. Based on the research results, the features of the process of ensuring the state’s information security in a hybrid war were studied and certain practical aspects of this issue were clarified.
Meziválečná výuka cizích jazyků na příkladu baťovské cizojazyčné školy
Authors: Kolumber Tereza , Zounek Jiří
Published: March 2023

Příspěvek se soustředí na výuku cizích jazyků v prostředí baťovského Zlína ve třicátých letech minulého století na příkladu soukromé cizojazyčné školy. Cílem příspěvku je prozkoumat, popsat a vysvětlit vznik a další vývoj cizojazyčné školy a rozvíjení jazykových schopností žáků v jejích podmínkách v období meziválečném. Metodologicky vycházíme z tradičně používaných metod historického výzkumu (metoda přímá a nepřímá). Vzdělávací instituci zkoumáme jak ze širších celospolečenských souvislostí, tak zároveň sledujeme každodenní život školy pomocí historiografického přístupu mikrohistorie. Předložená studie je rozdělena na tři části. Nejprve vysvětlujeme metodologii výzkumu, poté se zaměřujeme na faktory ovlivňující vznik a organizaci zkoumané cizojazyčné školy, a nakonec se zabýváme rozvíjením jazykových schopností žáků. Výsledky výzkumu ukazují úzké propojení vedení koncernu Baťa a života zkoumané školy. Výběr a způsob zprostředkování učiva nebyl determinován pouze potřebami výrobního podniku, ale i meziválečným reformním hnutím a novými přístupy k výuce cizích jazyků.
Atezolizumab (Tecentriq) for Alveolar Soft Part Sarcoma
Authors:   Editors from The Medical Letter
Published: March 2023

Atezolizumab (Tecentriq – Genentech), an immune checkpoint inhibitor, has been approved by the FDA for treatment of unresectable or metastatic alveolar soft part sarcoma (ASPS) in patients 2>=years old. It was previously approved for treatment of non-small cell lung cancer, small cell lung cancer, hepatocellular cancer, and melanoma (see Table 1). Atezolizumab is the first drug to be approved in the US for treatment of ASPS. ASPS is a rare disorder that affects mostly adolescents and young adults; <1% of soft tissue sarcomas are ASPS.
Fam-trastuzumab deruxtecan (Enhertu) for Breast Cancer
Authors:   Editors from The Medical Letter
Published: March 2023

Fam-trastuzumab deruxtecan-nxki (Enhertu – Daiichi Sankyo/AstraZeneca), which received accelerated approval by the FDA in 2019 for treatment of HER2-positive breast cancer based on its rate and duration of response, has been granted regular approval for treatment of adults with unresectable or metastatic HER2-positive breast cancer who received a prior anti-HER2-based regimen in the metastatic setting or in the neoadjuvant or adjuvant setting and developed recurrence during or within 6 months of completing treatment.
Innovation in Neurosurgery: Lessons Learned, Obstacles, and Potential Funding Sources
Authors: Lucke-Wold Brandon
Published: March 2023

Innovation is central to neurosurgery and has dramatically increased over the last twenty years. Although the specialty innovates as a whole, only 3-4.7% of practicing neurosurgeons hold patents. Various roadblocks to innovation impede this process such as lack of understanding, increasing regulatory complexity, and lack of funding. Newly emerging technologies allow us to understand how to innovate and how to learn from other medical specialties. By further understanding the process of innovation, and the funding that supports it, Neurosurgery can continue to hold innovation as one of its’s central tenets.
An integrated mobile application for enhancing management of nutrition information in Tanzania
Authors:   , Mduma Neema
Published: March 2023

Malnutrition contributes to over one half of the deaths of children under age of five years in developing countries and is the single greatest cause of child mortality in Tanzania. Studies reveal that, the issue of malnutrition is aggravated by lack of nutrition information especially in rural communities. Absence of proper tools makes collection, management and access to nutrition information very difficult. This study improves accessibility of nutrition information by taking advantage of the advanced mobile technologies and develops a system for managing nutrition information. The system was implemented using a mixed approach involving qualitative techniques whereby the requirements and fact finding was done through interviews and literature review. Unified Modelling Language (UML) technique was used to design and model the user requirements and system specification. PHP, MySQL, XML and Java were used to complement the development of this system. The developed mobile-based nutrition information management system was then integrated with existing Health Centre System and is able to provide a platform that gives mothers instant access to nutritional tips, allow them to interact with nutrition practitioners and help in record keeping. The results demonstrate the potential of using mobile technology for collection and delivering nutrition information in various sectors. In particular, this system could be adopted to improve prenatal and postnatal health in Tanzania and therefore help in bringing down the number of deaths of children under age of five. URI
A data analytic module for nutrition screening of children under five years in Tanzania
Authors:   , Nyanjara Sarah
Published: March 2023

Malnutrition is one of the major health problems in the world, and more prevalent in developing countries. The World Health Organisation (WHO) estimates that malnutrition is associated to half of all deaths of children under five years. In Tanzania it is estimated that 43,000 children die and the government loses up to Tsh. 700 billion annually due to the effects associated with malnutrition. Due to its unbearable consequences several international organisation have initiated collective measures to combat malnutrition. Nutrition screening, the process of identifying whether the child is malnourished or not, is a proven and important step towards malnutrition eradication. Regular and effective nutrition screening allows early malnutrition or risk of malnutrition to be identified and proper treatment and malnutrition management to be effected. The whole process of nutrition screening and malnutrition management in Tanzania still requires a lot of improvements. The studies show that the nutrition screening is not effective and it is mostly manual. The process includes the use of papers (clinic card) in recording anthropometrics measurement and that Mid Upper Arm Circumference (MUAC) is the only tool used for nutrition screening despite the already identified shortcomings. In this study, a nutrition data analytic module for nutrition screening for children under five years is proposed and developed. The system will have the ability to store child records after the child is registered, perform nutrition screening to identify if the child is well nourished or malnourished, and establish the current state of malnourished child in order to allow appropriate action to be taken by a health worker. Additionally the progress of malnourished child will be established to allow proper malnutrition management. The module has the ability to create reports which will help researchers, stakeholders and other users to get nutrition related data and information and malnutrition trends. This study puts in place a nutritional data analytic module for nutrition screening. This will facilitate effective nutrition screening of children and hence improve children nutrition health.
Development of radio frequency identification (RFID)-based drug management and monitoring system, case of public hospitals in Tanzania
Authors:   , Ishabakaki Prisila
Published: March 2023

Radio Frequency Identification (RFID) is the wireless technology which uses radio frequency waves to transfer data for the purpose of automatic identification and tracking the intended objects. Recently, the adoption of Radio frequency technology in health sector has been a field of major interest due to automatic data capturing and processing capability of the technology. RFID consists of reader and tag; the reader is used to capture information stored in tag and transfer it to the enterprise information system. RFID has recently been applied in hospitals to control and track hospital inventories, supply chain management and medication error controlling. However, the process is being done manually; paper-based documentation and records keeping are used. This manual work consumes time and resources which in turn presents difficulties during tracking and auditing. This scenario has therefore caused occurrence of incidences of drug theft and diversion by unfaithful health workers. In lieu of that, a system for management and monitoring the pharmaceutical supplies in hospital environment has been developed, in this study. The research started with review and analysis of the existing system and procedure in hospital pharmacy management and monitoring to exploit potential gap to be fulfilled by the proposed research. Then, the analysis of the problem domain was carried out to identify the system requirements that were used to design and implement RFID based drug monitoring and management system. The developed system was implemented and validated.
War in Ukraine: the case for environmental peacebuilding and reparations
Authors: Slobodian Nataliia
Published: March 2023

Russia�s current large-scale unprovoked invasion of Ukraine demonstrates that the environment matters, even though it is considered a secondary issue during conflicts. The war has dire consequences for people and nature, in both Ukraine and other European states. The Ukrainian case is viewed as a global system transformation factor: it has seen transboundary effects throughout the regions and the world. Of growing importance is the need to investigate the main principles and approaches in respect of environmental peacebuilding. We argue that this current war against Ukraine has proved that the world needs new approaches to sustainable peacebuilding, including environmental reparation and justice, and we propose a possible reparation mechanism through the world�s first Carbon Border Adjustment Mechanism (CBAM).
History of production and its challenges in the current era
Authors: Afanador Cubillos Nicolás
Published: March 2023

This qualitative and documentary research analyzes the significant advances that production and operations have had over time, seeking to establish the management approach's progress in each of the historical stages. It is possible to confirm that this has evolved from a perspective focused on manufacturing to a philosophy focused on a comprehensive view of the supply chain. This highlights the main obstacles to facing current challenges and, at the same time, points out the almost hegemonic short-term vision that has characterized production and operations management throughout the 20th century, as opposed to the demand current broader perspective.
Sonic architecture: auditory illusion of a visual memory in the shophouse 1527 for "a lost kitchen"
Authors:   , Nateekulcharoen Thanatchaporn
Published: March 2023

This thesis is a study of sound in relation to a theory of "EVERYDAY LIFE." It is a supplement to Paul Connerton’s view on architecture and memories written in a book entitled How Societies Remember. The ideas are that, first of all, objects, imageries, data can be converted to sound and vice versa. Secondly, sound is considered to be visual memories that exists in space and time. Lastly, it is possible to create a space of sound to exhibit a past life of a built environ. The intention of this study is to document the visual memories of the lost objects of the past owners in Samyan district, during the period of urban gentrification. Sound of a Lost Kitchen is recorded by using auditory illusion technique of Thai omelet cooking sound from performance upon things in real space. The proposed outcome of this study is to exhibit sound of "A Lost Kitchen" in an actual space, a temporary art house entitled the Shophouse 1527. The aim is to test the response of the visitors that feel through the perception of "Auditory Illusion" in real space. Sonic architecture, in this sense, is not only an attempt to use sound as a design tool but also to preserve the memories. In this thesis, I pay respect to architecture in relation to sound. The symbolism of Thai culture in everyday life reflects to the value of lost space as the preservation of memory. The analysis of the outcome is based on the audiences’ responses to the exhibition "A Lost Kitchen," particularly the cultural differences. All positive and negative responses are valuable for the future development.
The relationship between greenhouse gas emission and rice production in Thailand
Authors:   , Vitidladda Kitsada
Published: March 2023

Climate Change has been a global concern for decades. The phenomenon is mainly caused by human activities, including rice production. Although the agricultural activity can adversely emit greenhouse gas emission, it is also vital to Thai economy for a long time as well. This study has two objectives. The first objective is to examine the relationship between greenhouse gas emission and rice production in Thailand to evaluate the balance between economic and environmental aspects. The second objective is to study rice farming practices that can balance between greenhouse gas emission mitigation and rice farmers’ income. For the first objective, secondary, panel dataset from 2012 to 2017 at provincial level of Thailand is applied in Panel Data Regression Models, and Two-Stage Least Squares (TSLS) is also utilized to cope with potential two-way causality between rice production and emission. This study found that the variables are in N-shaped relationship, and only one-way casual effect from rice production to greenhouse gas emission is found. Additionally, while population density and final commercial energy consumption from oil are found to be positively related to greenhouse gas emission per capita, time trend shows a negative relationship with the emission. The N-shaped relationship suggests that a decrease greenhouse gas emission from rice production is only temporary as further growth will lead to higher emission. For the second objective, from systematic review, this study suggests no tillage, nitrogen fertilizers, and integrated rice-animal farming as alternative rice farming practices that can balance between economic and environmental aspects for rice production. Meanwhile, some practices such as slow-release fertilizer and biochar can generate even less greenhouse gas emission, but they are not economically profitable. Thus, the government should control their prices to make them profitable for farmers as they can generate positive externality to the environment.
Becoming artists (again)! : interview with Jean-Philippe Denis
Authors: Denis Jean-Philippe
Published: March 2023

In this interview, which closes the section dedicated to the role of publishing in the urgency of integrity, we wanted to capture the analysis of a professor with a great deal of experience in the world of publishing in the broad sense. Jean-Philippe Denis is committed to the promotion of French-speaking management research and the way in which management sciences can and should inform public debate. Jean-Philippe Denis is Editor-in-Chief of the Revue française de gestion since 2013. This multidisciplinary journal, in line with the original knowledge project of management sciences (explanatory, but also prescriptive and critical), is the leading French-speaking scientific publication in the field of management. Jean-Philippe Denis has also created an audiovisual laboratory dedicated to the scientific valorization IQSOG - Fenêtres Ouvertes sur la Gestion. In this capacity, he conducts academic interviews for Xerfi Canal and more than 800 capsules have been broadcast in some seven years. The third part of his commitment consists in being co-director of collections ("Grands auteurs francophones" and "Lectures, relectures") at Éditions Management & Société (EMS).
Proses Sosialisasi Bahaya Mikroplastik Melalui Portal Berita Online (Studi Evaluatif Dengan Pendekatan Model Public Relations)
Authors: Rizky Rosalina , Ronaldo Randy , Muhammad Kholid Basyaiban, S.H
Published: March 2023

Permasalahan yang sedang mendunia yaitu pencemaran lingkungan yang bersumber dari sampah plastik sekali pakai kemudian terfragmentasi menjadi mikroplastik. Dampak nyatanya dari permasalahan tersebut yang terjadi kemungkinan buruk ialah kerusakan ekosistem laut. Permasalahan tersebut menjadi tugas masyarakat untuk memperhatikan secara serius, maka dari itu peneliti tertarik untuk mengkaji proses sosialisasi bahaya mikroplastik melalui portal berita online. Kajian teoritis menggunakan model public relations dari Gruing & Hunt. Pendekatan penelitian menggunakan kualitatif dengan jenis penelitian deskriptif. Informan dalam penelitian yaitu beberapa jurnalis portal berita online dan staff legal ECOTON. Pada penelitian ini, metode pengumpulan data didapatkan dari data primer dan data sekunder. Analisis model public relations dalam proses sosialisasi mikroplastik yang cenderung diterapkan pada laman berita online kepada khalayak umum dapat dilihat dari empat karakteristik yang meliputi tujuan, sifat/arah komunikasi, model komunikasi dan penelitian 1. Tujuan Media Online 2. Sifat/Arah Komunikasi 3. Model Komunikasi 4. Penerapan Penelitian.
Intersection of Heritage, Water, and the Work of the ICOMOS Sustainable Development Goals Working Group
Authors: Caballero Gabriel , Colvile Bretony , Perez-Alvaro Elena , Dharshini Saranya
Published: March 2023

The Sustainable Development Goals Working Group (SDGWG) of the International Council on Monuments and Sites (ICOMOS) advocates for heritage by publishing reports, attending conferences and engaging in networking. The SDGWG is particularly interested in how water, heritage and sustainable development intersect. Various aspects of this intersection are demonstrated by three case studies of underwater cultural heritage: a study of submarine cables and pipelines, the traditional floating garden system of chinampas in Mexico City, and the indigenous water tanks of kulams and gender-associated stepwells in India. This paper examines the current state of protection and advocacy, while also discussing the challenges faced by water heritage. While significant challenges remain, the SDGWG is developing solutions to ongoing and sometimes overlooked problems.
Organizational fairness and task performance: a study between different activities and positions in the justice sector
Authors: Santos Edicreia Andrade dos , Venturini Lauren Dal Bem , Sallaberry Jonatas Dutra , Klein Luciana , Flach Leonardo
Published: March 2023

Purpose: This study analyzes the effects of organizational justice on the performance of tasks in the justice sector, divided by activity and position.
Design/methodology/approach: We applied structural equations to a sample of 474 employees of the Public Prosecutor.
Findings: A direct and positive effect of distributive justice and interactional justice on task performance was discovered. However, aspects of procedural justice do not have a significant relationship with task performance. The performance of non-core activities is positively influenced by interactional justice and the final activity by distributive justice. As for the positions, the interactional dimension has a significant magnitude in the position of analyst, while the distributive and procedural justice affect the performance of the technician's positions.
Practical implications: These findings provide an understanding of how organizations can build their organizational structure between middle and end activities, to increase the perception of justice of their servers, and consequently improving the performance of activities.
Originality: The article explores in an unprecedented way the perception of organizational justice in different work functions - the core activity and the non-core activity.
Marketing Mix Strategy and Financial Capabilities in Improving Sharia Stock Investment
Authors: Istikomah Istikomah , Saputra Ginanjar Wira , Yusuf Muhammad
Published: March 2023

Every year the capital market in Indonesia is increasing, stocks are the investment of choice for investors. To accommodate the needs of Muslims in Indonesia, middle class people with limited financial capabilities have begun to switch to choosing Sharia shares. This study aims to determine the Marketing Mix Strategy in the form of product, price, location and promotion and Financial Capability is the right model to improve Sharia Stock Investment Decisions. This study uses a qualitative descriptive analysis method, namely by collecting data directly from PT. Syirkah Griya Berkah by conducting observations, interviews according to the object of research. The results of this study indicate that the strategy implemented by the company has been going well from the targeted 100 investors, recorded 67 who have joined, where the four Marketing Strategy Variables and Financial Capability support each other and complement each other in improving Sharia Stock Investment Decisions. must further improve its strategy to compete with other stock competitors.
Analysis of the Recruitment of Members of the Indonesian National Police (Case Study of the West Java Regional Mobile Brigade)
Authors: Suarha Cecep
Published: March 2023

This study aims to determine, describe and analyze the Recruitment of Members of the Indonesian National Police in Brimob related to the recruitment process, the source of recruitment, the factors that must be considered in the selection, the problems found in the selection and the role of recruitment and selection. The research method used in this study is a descriptive research method with a qualitative approach. The data collection techniques used in this study were interviews, observation and documents. Based on the results of research and discussion, it was concluded that the Recruitment Analysis of the Members of the Indonesian National Police (Case Study of the West Java Regional Mobile Brigade) in the Recruitment Process Brimob members from AKPOL, BINTARA, and TAMTAMA, still have not carried out the selection of members of the National Police especially in Brimob successively or every year there is no Brimob quota opening so there is a shortage of Polri personnel in Brimob, there are still participants who did not prepare themselves for selection, especially in health from starting to check eyes, teeth, tonsils, varicoceles and varicose veins, there are still participants who after graduating from selection and continued with police education but in the education process must be excluded due to mental factors, stress , and other health, there are still members who after graduating from general education, were then transferred to Brimob quite a bit on the grounds that Brimob was always assigned out of Java and demanded daily for training.
Virtual Screening on Indonesian Herbal Compounds as SARS-CoV-2 Spike (S2) Glycoprotein Inhibitors: Pharmacophore Modelling & Molecular Docking Approaches
Authors:   Universitas Indonesia, Sugito Syailendra Karuna , Cristina Artha Uli ,   Universitas Indonesia, Harimurti Putri Saskia ,   Universitas Indonesia, Cendani Gabriella Regita ,   Universitas Indonesia, Insani Fauzi Azhar ,   Universitas Indonesia, Erlina Linda ,   Universitas Indonesia, Paramita Rafika Indah ,   Universitas Indonesia, Fadilah Fadilah ,   Universitas Indonesia
Published: March 2023

Background: There are still no specific treatments for coronavirus disease (COVID-19) until present days. Several studies have been conducted to determine whether herbal medicine can be an option to be used as a definitive medicine for COVID-19. S2 subunit of spike protein which is responsible for SARS-CoV-2 entry to the host cell, is a potential drug target to inhibit the viral infection. In this study, we aimed to find some compounds from the HerbalDB database that have potential as SARS-CoV-2 spike (S2) glycoprotein inhibitor. Methods: The 6LXT protein was used as the target protein. The procedure in this study consisted of these following steps: protein and ligand preparation, pharmacophore modelling and compound screening, molecular docking, ADME, and toxicity analysis. The docking of hit compounds to the target protein were compared to arbidol and quercetin as positive controls. Results: Four hit compounds were screened from HerbalDB compounds. Two of them, octopamine and L-noradrenaline, showed lower binding energies (respectively, -5.19 and -4.98 kcal/mol) than positive controls whereas the other two compounds, mimosine and L-theanine, showed higher binding energies (respectively, -3.99 and -3.62 kcal/mol) compared to positive controls. Mimosine, L-noradrenaline, octopamine, and L-theanine had toxicity classes of IV, II, IV, and IV, respectively. Conclusion: Octopamine shows the best potential as SARS-CoV-2 spike (S2) glycoprotein inhibitor. However, this compound also poses several toxicity risks and therefore, needs a more elaborate considera-tion upon using. There are still no specific treatments for coronavirus disease (COVID-19) until present days. Several studies have been conducted to determine whether herbal medicine can be an option to be used as a definitive medicine for COVID-19. S2 subunit of spike protein which is responsible for SARS-CoV-2 entry to the host cell, is a potential drug target to inhibit the viral infection. In this study, we aimed to find some compounds from the HerbalDB database that have potential as SARS-CoV-2 spike (S2) glycoprotein inhibitor.
Potential of Dietary Flavonoids in The Prevention and Therapy of COVID-19 : Focusing in Mast Cell - Calcium Ion Channel Axis
Authors:   Universitas Indonesia, Tedjo Aryo
Published: March 2023

Syndrome Acute Respiratory Syndrome Corona Virus-2 (SARS COV2) is the virus that causes the COVID19 disease and has caused more than 4 million deaths worldwide. This virus infects the host cell through the interaction between the virus’s glycoprotein S molecule with the ACE2 which is the virus receptor, binding, undergoes membrane fusion and enters the cell and replicates in it. Currently, several strategies used in developing anti-viral compounds are targeting compounds that play a role in the process of entering the virus into host cells such as ACE2, S glycoprotein, and TMPRSS2, while some target main proteases such as RNA dependent Polymerase and N proteins. On the other hand, one of the causes for the worsening of COVID-19 cases is hyperinflammation. This condition can also be caused by an increase in calcium consumption activity which is responsible for the process of viral endocytosis, mast cell recruitment, and also the recruitment of surrounding cells to form syncytia. Under these conditions, virions that are trapped and accumulated in the syncytia can initiate the release of virions and pro-inflammatory molecules, leading to hyperinflammation and second week crash. This review will explain the importance of the role of calcium ions and mast cells in mediating inflammation as well as the prospect of inhibiting hyperinflammation in COVID19 using flavonoid compounds contained in daily food ingredients.
Autofluorescence imaging permits label-free cell type assignment and reveals the dynamic formation of airway secretory cell associated antigen passages (SAPs)
Authors: Shah Viral S , Hou Jue , Vinarsky Vladimir , Xu Jiajie , Surve Manalee V , Lin Charles P , Rajagopal Jayaraj
Published: March 2023

The specific functional properties of a tissue are distributed amongst its component cell types. The various cells act coherently, as an ensemble, in order to execute a physiologic response. Modern approaches for identifying and dissecting novel physiologic mechanisms would benefit from an ability to identify specific cell types in live tissues that could then be imaged in real time. Current techniques require the use of fluorescent genetic reporters that are not only cumbersome, but which only allow the study of three or four cell types at a time. We report a non-invasive imaging modality that capitalizes on the endogenous autofluorescence signatures of the metabolic cofactors NAD(P)H and FAD. By marrying morphological characteristics with autofluorescence signatures, all seven of the airway epithelial cell types can be distinguished simultaneously in mouse tracheal explants in real time. Furthermore, we find that this methodology for direct cell type-specific identification avoids pitfalls associated with the use of ostensibly cell type-specific markers that are, in fact, altered by clinically relevant physiologic stimuli. Finally, we utilize this methodology to interrogate real-time physiology and identify dynamic secretory cell associated antigen passages (SAPs) that form in response to cholinergic stimulus. The identical process has been well documented in the intestine where the dynamic formation of SAPs and goblet cell associated antigen passages (GAPs) enable luminal antigen sampling. Airway secretory cells with SAPs are frequently juxtaposed to antigen presenting cells, suggesting that airway SAPs, like their intestinal counterparts, not only sample antigen but convey their cargo for immune cell processing.
Hypoxia-induced tracheal elasticity in vector beetle facilitates the loading of pinewood nematode
Authors: Tang Xuan , Zhou Jiao , Koski Tuuli-Marjaana , Liu Shiyao , Zhao Lilin , Sun Jianghua
Published: March 2023

Many pathogens rely on their insect vectors for transmission. Such pathogens are under selection to improve vector competence for their transmission by employing various tissue or cellular responses of vectors. However, whether pathogens can actively cause hypoxia in vectors and exploit hypoxia responses to promote their vector competence is still unknown. Fast dispersal of pinewood nematode (PWN), the causal agent for the destructive pine wilt disease and subsequent infection of pine trees, is characterized by the high vector competence of pine sawyer beetles (Monochamus spp.), and a single beetle can harbor over 200,000 PWNs in its tracheal system. Here, we demonstrate that PWN loading activates hypoxia in tracheal system of the vector beetles. Both PWN loading and hypoxia enhanced tracheal elasticity and thickened the apical extracellular matrix (aECM) of the tracheal tubes while a notable upregulated expression of a resilin-like mucin protein Muc91C was observed at the aECM layer of PWN-loaded and hypoxic tracheal tubes. RNAi knockdown of Muc91C reduced tracheal elasticity and aECM thickness under hypoxia conditions and thus decreasing PWN loading. Our study suggests a crucial role of hypoxia-induced developmental responses in shaping vector tolerance to the pathogen and provides clues for potential molecular targets to control pathogen dissemination.
Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
Authors: Boyle Kieran A. , Polgár Erika , Gutierrez-Mecinas Maria , Dickie Allen C. , Cooper Andrew H. , Bell Andrew M. , Jumolea M. Evelline , Casas-Benito Adrian , Watanabe Masahiko , Hughes David I. , Weir Greg A. , Riddell John S. , Todd Andrew J.
Published: March 2023

Somatosensory information is processed by a complex network of interneurons in the spinal dorsal horn. It has been reported that inhibitory interneurons that express neuropeptide Y (NPY), either permanently or during development, suppress mechanical itch, with no effect on pain. Here we investigate the role of interneurons that continue to express NPY (NPY-INs) in adulthood. We find that chemogenetic activation of NPY-INs reduces behaviours associated with acute pain and pruritogen- evoked itch, whereas silencing them causes exaggerated itch responses that depend on cells expressing the gastrin-releasing peptide receptor. As predicted by our previous studies, silencing of another population of inhibitory interneurons (those expressing dynorphin) also increases itch, but to a lesser extent. Importantly, NPY- IN activation also reduces behavioural signs of inflammatory and neuropathic pain. These results demonstrate that NPY-INs gate pain and itch transmission at the spinal level, and therefore represent a potential treatment target for pathological pain and itch.
Transcriptome of the pygmy grasshopper Formosatettix qinlingensis (Orthoptera: Tetrigidae)
Authors: Liu Yuxin , Li Xuejuan , Lin Liliang
Published: March 2023

Formosatettix qinlingensis (Zheng, 1982) is a tiny grasshopper endemic to Qinling in China. For further study of its transcriptomic features, we obtained RNA-Seq data by Illumina HiSeq X Ten sequencing platform. Firstly, transcriptomic analysis showed that transcriptome read numbers of two female and one male samples were 25,043,314, 24,429,905, and 25,034,457, respectively. We assembled 65,977 unigenes, their average length was 1,072.09 bp, and the length of N50 was 2,031 bp. The average lengths of F. qinlingensis female and male unigenes were 911.30 bp, and 941.82 bp, and the N50 lengths were 1,745 bp and 1,735 bp, respectively. Eight databases were used to annotate the functions of unigenes, and 23,268 functional unigenes were obtained. Besides, we also studied the body color, immunity and insecticide resistance of F. qinlingensis. Thirty-nine pigment-related genes were annotated. Some immunity genes and signaling pathways were found, such as JAK-STAT and Toll-LIKE receptor signaling pathways. There are also some insecticide resistance genes and signal pathways, like nAChR, GST and DDT. Further, some of these genes were differentially expressed in female and male samples, including pigment, immunity and insecticide resistance. The transcriptomic study of F. qinlingensis will provide data reference for gene prediction and molecular expression study of other Tetrigidae species in the future. Differential genetic screening of males and females provides a basis for studying sex and immune balance in insects.