bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Skill of SPSS Software For Biology 3rd Year Students of Samara University in 2021: Action Research
Authors: Asfaw Aragaw , Hailu Abdu , Awol Hussen
Published: May 2022

SPSS helped revolutionize research practices in the social sciences. Students in Department of Biology think that SPSS statistical software is very difficult for them, because SPSS statistical software is viewed as a hard science than Biology which is viewed as a soft science. The main aim of this action research is to improve the skill of SPSS software’ in the case of biology of third year Biology section A students at the Samara University in 2021. Among all 46, 35 students were included since they are present on the day of training class. The data from the student’s questionnaire were tabulated and analyzed using descriptive statistical method. For the purpose of analyzing the collected data SPSS version 20 software was used. From the summary statistics of the total 35 students the proportion of male and female students is 5(14.3%) and 30(85.7%) respectively. The residence of the student majority 22 (62.9%) comes from rural areas. Of students 23 (65.7%) are motivated for their future research works to use it for statistical data analysis and graphics. There is high demand SPSS training programs for students   as it is mandatory for data analysis. Software training programs like SPSS should be proposed on the curriculum to improve the skill of the students.
A Study on Mathematics Lesson Design of Prospective Elementary School Teachers by Using Latent Profile Analysis
Authors:   The Korea Society Of Educational Studies In Mathematics, Jin Sunwoo
Published: May 2022

Although interest in lesson design has been increasing among mathematics teachers, there is a lack of research on how to analyze the mathematics lesson design. Given this backgound, this study explored prior studies to extract four elements for analyzing lesson design and collected 104 lesson plans from prospective elementary school teachers in order to investigate their ability and characteristics of mathematics lesson designs. This study then analyzed their lesson plans by using Latent Profile Analysis (LPA) with four elements (i.e., understanding of mathematical tasks, considering students’ mathematical thinking, connecting to mathematics content, and assessment). The results show that mathematics lesson plans designed by prospective elementary school teachers could be classified into three types: a lesson design that lacks understanding of learning goal and students’ mathematical thinking, a lesson design that indicates superficial consideration of students’ mathematical thinking, and a well-prepared lesson design with all of the elements. Based on the results, this study discusses the mathematics lesson designs of prospective elementary teachers as well as subsequent research.
A Delphi Study to Develop Scenario-Based Assessment Framework of Mathematical Attitude and Practice
Authors:   The Korea Society Of Educational Studies In Mathematics, Kim Sun Hee , Rim Haemee , Kim Yun Min , Hwang Ji Hyun , Kim Su Min , Kim Chul Min
Published: May 2022

In this study, a Delphi survey was conducted to generate the framework of a mathematics competency, called Attitude and Practice. Sixteen participants in the two consecutive rounds of the Delphi survey included mathematics education expert in student affect or educational psychology, and in-service mathematics teachers with a master’s degree or higher. We first established the definition of Attitude and Practice and identified their components while securing validity evidence from the Delphi survey results. Attitude and Practice are the competency to engage in mathematical activities with the joy and passion of doing mathematics as an individual or a group. Next, we characterized the components of Attitude and Practice as follows: (1) pleasure of learning mathematics, including interest, self-efficacy, and meta-affect (2) passion for mathematics including perseverance and seeking challenges, (3) doing mathematics together, including resolving conflicts and motivation for collaboration, and (4) global citizenship and enjoying mathematics culture. We defined and validated the specific components with the literature review and the Delphi survey responses. The results of this study will serve as a foundation of research to develop scenario-based assessments for students’ attitudes and practices. Furthermore, the framework established in this study can provide insights into the evaluation of mathematics competency of Attitude and Practice regarding Korean mathematics educators who have experienced difficulties in defining and assessing Attitude and Practice.
Student team achievement division model (STAD) in increasing human digestive system learning outcomes
Authors: Putri Anggita Dwi Yusvi , Sudibyo Elok
Published: May 2022

This study aims to implement the STAD learning model to improve student learning outcomes and student responses. The STAD model was applied to 29 Semen Gresik Junior High School students. The research design used was one group pretest-posttest design with data collection methods using a test, questionnaire, and observation methods. The research instruments were learning sheets, pretest questions, and student response questionnaire sheets. The study found an increase in learning outcomes through the calculation of N-Gain with an average value of 0.85 in the high category. Student responses in learning activities using the STAD method showed very positive results, with an average percentage of 92%. The application of the STAD learning method was very good at meetings I and II. Based on the research data analysis, it can be concluded that there is an increase in learning outcomes through the STAD type cooperative learning model in the material of the human digestive system.
O que Significa Crer Hoje
Authors: Koop Pedro Paulo
Published: May 2022

«Ficai sabendo vós todos que não há sob o céu outro nome dado aos homens pelo qual possam ser salvos, fora do nome de Jesus Cristo Nazareno» (At 4,10-12). Nesta confissão de Pedro captamos o eco do primeiro anúncio cristão. Da parte de Deus, a Salvação de todo homem é dada somente em Jesus de Nazaré. Este anúncio de fato fez, e ainda faz, história...
Os Conceitos Cristãos de Liberdade e Libertação
Authors: Comblin José
Published: May 2022

Desde há séculos o tema da liberdade está no centro da cultura e da vida do Ocidente. Porém o mesmo tema nunca foi proposto, estudado e exaltado com tanta insistência como nos últimos anos. Aos olhos dos nossos contemporâneos a história é fundamentalmente um movimento de procura da liberdade, isto é, um movimento de libertação; isto quer dizer que para eles o que vale na história é a conquista da liberdade...
O Padre Católico, visto pelos indígenas do Brasil e do Maranhão
Authors: Hoornaert Eduardo
Published: May 2022

Um dos aspectos a serem esclarecidos em relação à evangelização do Brasil é o da comunicação entre o evangelizador e seu “ouvinte”. Evangelização, por ser movimento de uma pessoa para outra(s), implica comunicação. Ora, sabemos que existem problemas de comunicação entre as pessoas: frequentemente uma mensagem é entendida de maneira diferente pelo ouvinte por causa da diferente estrutura mental, da cultura, do ambiente...
A study of 100 children with intussusception in Misan
Authors: Mowheba Saeed Shuker  , Ali Abdulnabi Abdulhassan  , Bassam Hamed Sweedan
Published: May 2022

In early childhood the commonest cause of bowel obstruction is intussusception. A total of 100 children of intussusception were managed during the period from January 2014 to October 2018, male (73) and female (27). Those children were subjected to ultrasonic for diagnosis of intussusception. Results revealed that the common symptoms were excessive cry (87%), vomiting (77%) blood in stool (52%). Ileocolic intussusception (97%) was the commonest type. Ninety five children of the present study underwent hydrostatic reduction (with salie enema done after inflation of Foleys catheter in the rectum and flowing saline through it). The hydrostatic reduction was successful in seventy-one children (71%). Twenty nine children (29 %) needed surgery. The median hospital stay was 2 days and children (75%) went home within 48 hrs. Eight children (8%) of the study population developed complications. (1%) had shock. (5%) had perforation, 1% peritonitis and 1% septicaemia.
An educational intervention to improve nurses’ knowledge and self-confidence: An integrated literature review
Authors: Angela Nwabuzor Ikeme
Published: May 2022

Purpose: To provide educational intervention to improve the knowledge and self-confidence of nurses in ambulatory and urgent care clinics in detecting early deterioration, intervening, and evaluating changes in patient condition using a consistent assessment tool. A review of the organization policy indicated a process to call the medical alert response team (MAR). However, there was no established algorithm for nurses to escalate or implement interventions when they noticed a change in a patient condition. An informal survey of ten assistant nurse managers in the ambulatory and urgent care clinics asked about their calling process for MAR and what interventions are used yielded inconsistent practices across the board. An unofficial survey of clinic nurses suggested a lack of knowledge and self-confidence in nurses for recognizing and implementing appropriate intervention when there is a change in a patient condition. Method: Extensive literature search using CINAHL and PubMed databases for peer-reviewed articles relevant to the topic. Results: An educational intervention that enhances nurses’ knowledge and self-confidence in recognizing and activating appropriate intervention empowers nurses to utilize critical thinking and clinical judgment to provide high quality and safe care to their patients, thus decreasing failure to resuscitate. Conclusions and Implications to practice: There is a need to provide educational intervention to improve the knowledge and self-confidence of nurses in ambulatory and urgent care clinics in detecting early deterioration, intervening, and evaluating changes in patient condition using a consistent assessment tool.
The effect of hot water exctact of Linum usitalissimum and Trigonlla foenum-graecum on bacteria that isolated from mouth
Authors: Mohammed A AL-Jaleel  , Anmar Saadi Aboud  , Alyaa Muhsin Yousif
Published: May 2022

Research was done in Laboratories of biology department-collage of check antibacterial activity of hot water extract of flax seed (Linum usitalissimum) and fenugreek seed (Trigonella foenum-graecum) against bacteria that isolated from mouth by using holes method on nutrient agar. Extracts was prepared of seeds of plants that studying in stoke then bacteria that isolated from mouth of different people in different age categories and do different habits such as (drinking wine ,un brush teeth regularly ). Some species of bacteria were diagnosis in this experiment which were (pseudomonas spp. Staphelococcus and Streptococcus spp.) this experiment were measured the diameter of inhibition zone around the holes in petri dishes. Both extracts of Linum and Trigonella seed showed an antibacterial activity against bacteria in study, also the Trigonella seed extract present more effective than Linum seed extract on bacteria.
Pharmacy students’ knowledge in the use of glutathione for multiple sclerosis
Authors: Nwabuoku Jessica  , Michelle G Boateng  , Maada Jajua  , Bisrat Hailemeskel
Published: May 2022

Objective: To determine first-year pharmacy students’ knowledge of the role of dietary and herbal supplements such as glutathione (GSH) on Multiple Sclerosis (MS). Methods: Forty-two first-year pharmacy students were asked to complete an online survey to assess their knowledge of the use of GSH in the treatment of MS using Likert-scale type questions. Results: Participants were given an optional survey which received a 100% response. The majority of the participants were between the ages of 24 and 26 (n=17, 40.5%), females (n=27, 64.3%); located in the DMV area and had a BA/BSc degree (n=34, 81%) before joining the pharmacy program. The majority of the participants had a full-time job (n=21, 50%) with over one-third with pharmacy-related jobs (n=16, 38.10%) and an annual income of <$10,000 (n=13, 31.0%). The student participants were asked five knowledge questions to analyze their knowledge of the use of GSH. The five knowledge questions were 1. Use of GSH to prevent MS-induced damage; 2. Free radicals as causes of MS; 3. GSH release in MS; 4. The beneficial effect of GSH in MS; and 5. Limitation of GSH in MS. A passing score of 75% or higher was achieved in only a small percentage of student participants (n=14; 33.3%). When asked the knowledge questions, more than seventy percent (70%) of student participants answered at least one of the questions incorrectly with an overall average knowledge score of 56.7%. Question #2 answered by most of them yielding a percentage of 76.2%. Student participants age 24-26 (n=15, 26.2%) significantly agreed to the same question (p-value = 0.007). A small amount of the study participants (n=13; 31.06%) who worked for 1-2 years also significantly agreed to question #3 (p-= 0.010). More than half of the participants between 21 to more than 29 years old and who had worked at least 1-2 years agreed to question #2. Conclusion: Our results indicate that first-year pharmacy students have limited knowledge on the use of glutathione in the treatment of MS. On the knowledge questions, only a small number of participants received a passing score of 75% or higher. The average score was 56.7%. This signifies that there are many areas for improvement. The use of GSH is expanding its use from a dietary supplement to possible treatment of disease states such as MS. Students may have limited knowledge on the use of GSH may be due to lack of exposure in the pharmacy curriculum as first-year professional students.
MENINGKATKAN KOMUNIKASI MATEMATIS MELALUI MODEL PEMBELAJARAN KOOPERATIF TIPE JIGSAW
Authors: Pasandaran Rio Fabrika , Basir Fahrul , Suciati Indah
Published: May 2022

Komunikasi matematis merupakan komponen penting dalam mendukung pencapaian hasil belajar matematika peserta didik di sekolah. Esensi komunikasi matematis adalah proses penyampaian gagasan matematika baik secara lisan maupun tulisan, dari satu bentuk ke bentuk yang lain. Perubahan bentuk-bentuk simbol, gambar, diagram, tabel yang mewakili proses mental setiap peserta didik akan dibentuk menggunakan Model Pembelajaran Kooperatif Tipe Jigsaw (sebagai perlakuan). Tipe Jigsaw diyakini memiliki kontribusi positif terhadap perkembangan komunikasi matematis. Penelitian ini dilaksanakan di SMPN 5 Palopo, dengan metode eksperimen dan desain One - Group Pretest Posttest Design.  Komunikasi matematis peserta didik sebelum diberikan perlakuan berada pada kategori rendah dengan skor rata-rata 43,90 dan setelah diberikan perlakuan berada pada kategori sedang dengan skor rata-rata 75,31. Secara inferensial, melalui uji statistik One-Sample Test  diperoleh nilai signikansi sebesar 0.001 < 0.05.  Disimpulkan bahwa terjadi peningkatan komunikasi matematis peserta didik secara signifikan melalui model pembelajaran kooperatif tipe Jigsaw.
PENERAPAN MODEL PEMBELAJARAN BERPIKIR INDUKTIF TERHADAP HASIL BELAJAR MATEMATIKA SISWA SMP
Authors: Nurlinda Nurlinda , Nirfayanti Nirfayanti
Published: May 2022

Pembelajaran matematika masih didominasi dengan model pembelajaran yang konvensional, sebagian siswa terbiasa melakukan kegiatan belajar berupa proses menghafal tanpa dibarengi dengan penguasaan konsep matematika. Model pembelajaran pun berperan penting untuk menunjang keberhasilan proses pembelajaran yang dilakukan guru di dalam kelas. Salah satu penyelesaian yang dapat diusahakan yaitu dengan menerapkan model pembelajaran berpikir induktif. Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan penerapan model pembelajaran berpikir induktif dalam pembelajaran matematika pada siswa SMP Negeri 19 Moncongloe. Metode yang digunakan dalam penelitian ini adalah penelitian kuantitatif dengan metode eksperimen. Subjek penelitian ini adalah siswa-siswi kelas VII.1 SMP Negeri 19 Moncongloe yang berjumlah 21 orang. Instrumen yang digunakan adalah tes hasil belajar yang telah divalidasi oleh validator dan lembar observasi penilaian yang digunakan oleh observer. Statistik yang digunakan untuk pengujian adalah statistik deskriptif dan inferensial. Hasil penelitian diperoleh nilai rata-rata pretes dan posttest masing-masing adalah 69 dan 82,24. Hasil data pada penelitian ini berdistribusi normal dan hasil uji hipotesis diterima (H1 diterima). Sehingga ada pengaruh yang signifikan terhadap hasil belajar siswa kelas VII.1 SMP Negeri 19 Moncongloe setelah diajar dengan menerapkan model pembelajaran berpikir induktif. Oleh karena itu, terdapat perbedaan penerapan model pembelajaran berpikir induktif sebelum dan sesudah diterapkan pada siswa kelas VII.1 SMP Negeri 19 Moncongloe.
Il museo MEMO 4345 di Borgo San Dalmazzo. Intervista ad Adriana Muncinelli
Authors: Boccalatte Paola
Published: May 2022

A Borgo San Dalmazzo è presente da anni un memoriale che segna una pagina tragica della storia della città, ricordando come tra il 1943 e il 1944 la città avesse ospitato un campo di transito per ebrei italiani e stranieri. Dal 2021, a pochi passi dal memoriale, è inaugurato un museo, MEMO 4345, che racconta quella storia e soprattutto la storia delle persone che da lì furono deportate nei campi di sterminio. Un museo di storia, che promuove una decisa riflessione anche su temi purtroppo ancora attuali, sulla guerra, sul razzismo, sulle radici dell’odio.
INSIEME. Il podcast dedicato ai luoghi della cultura popolare
Authors: Mitrugno Giulia
Published: May 2022

Esistono in Italia centinaia di luoghi che hanno assistito alla nascita della cultura popolare. Spesso sono posti che frequentiamo senza nemmeno conoscerne il passato. “INSIEME” è il podcast che racconta le storie di questi luoghi e di donne e uomini che continuano a essere testimoni e custodi di quella cultura popolare che appartiene a tutti noi. E in tutte queste storie c’è la stessa chiave per il successo: l’agire comune. Insieme.
Migrazioni nella periferia di Regime. L’estate del 1940: i «Tripolini» nella colonia post-sanatoriale di Tresigallo
Authors: Muroni Giuseppe
Published: May 2022

La migrazione di tredicimila bambini italiani tra i quattro e i dodici anni dalla Libia alla madrepatria, pochi giorni prima dello scoppio della seconda guerra mondiale, è rimasta per molti decenni una microstoria nota soprattutto all’interno della comunità degli ex coloni. Viene qui ripreso il percorso di riscoperta della vicenda, la situazione coloniale in Libia, il ritorno in patria dei «bimbi libici» e l’accoglienza nelle colonie della costa tirrenica ed adriatica. La narrazione è arricchita di interviste e materiale documentario inedito.
Colour psychology in kindergarten classroom
Authors: Thung Chin Xing , Ahmad Hakimi
Published: May 2022

The research was conducted to explore the colour that can create a calm and peaceful environment in kindergarten classroom. Colour is the mood of a space as each colour has its own meaning. Hence, the colour used in every space need to suit with the activity done in the space. Kindergarten is among many other spaces that used colour a lot because children like colour and will be attracted by colour, especially bright colour. Kindergarten classroom is one of the spaces that preschool children stay in most of time, hence, the colour scheme required careful consideration to calm down children and let them concentrate on learning. From the previous research, it was found that researcher mainly focus on kindergarten design, kindergarten furniture design or on colour design in other interior spaces, such as restaurant, office, and hospital. Hence, the research gap for the will be the colour in the kindergarten classroom which can create a calm and peaceful environment. As there are different colour scheme for interior design, the most suitable colour scheme had identified for the kindergarten classroom to make the preschool children can calm down and pay attention in the classroom. The research concludes that the light green and light blue colour is the ideal colour for a calm and peaceful kindergarten classroom.
A New Direction of Islamic Education in Indonesia: Opportunities and Challenges in the Industrial Revolution Era 4.0
Authors: Akrim Akrim
Published: May 2022

This article aims to discuss the dynamics of development and discourse of Islamic education in studying with a futuristic approach, how the challenges and opportunities of Islamic education in the Revolutionary Era 4.0 are commonly referred to as the Era of Disruption. The method used is qualitative research method with library approach, the primary source used is literature, journals, and books related to the topic discussed. The discussion results showed various forms of opportunities and challenges faced by Islamic education in Indonesia, especially in the era of disruption, whose signs begin with globalization. Despite many options, Islamic education should also be wary of challenges. This study found various challenges, namely the ability of Islamic education to harmonize divine verses with kauniyah verses, maintaining the process of Islamization of science. Harmonize the God-human relationship in the form of a the-anthropo-centric education with the point of the press; man is a noble being of God. Harmonizing between faith and knowledge cannot be separated. He is adjusting between the fulfillment of spiritual needs (spiritual-ukhrowi) and the realization of physical (material-earthly) needs and harmonizing between revelation and intellect (thinking, critical and rational).
بيت الإعتدال الديني ونشر قيم الوسطية في مرحلة الجامعـية
Authors: Anwar Rosihon , Rusyana Ayi Yunus , Kodir Aceng Abdul , Purnama Agung
Published: May 2022

تبحث هذه الدراسة في فكرة الإعتدال الديني ودور بيت الإعتدال الديني في جامعة كمؤسسة خاصة بجامعة سونان جونونج جاتي الإسلامية الحكومية باندونج إندونيسيا في تجسيد فكرة الوسطية والإعتدال الديني في إندونيسيا. وباستخدام المنهج الوصفي، تستكشف الدراسة مفهوم بيت الإعتدال وتطبيقها في نشر وتكريس القيم الإسلامية النبيلة التي تؤكد على وسطية الإسلام. ومن خلال بيت الإعتدال الديني، تضع الجامعة نفسها كمؤسسة تعليمية دينية في طليعة تنفيذ وتعزيز الوسطية. وقد ظهر ذلك من خلال عملية التدريس والتعلم وتقوية المناهج الدراسية والتدريب والبحث عن القيم الدينية المعتدلة.
Parenting Patterns in Educating Children's Prayer Discipline During the Coronavirus Disease (Covid-19)
Authors: Tabroni Imam , Munajat Nano , Uwes Sanusi , Rostandi Usep Dedi
Published: May 2022

Children's discipline to perform the five daily prayers is often ignored by parents as the first educators at home during the Covid-19 pandemic. The purpose of this study was to determine parenting patterns in applying the discipline of five daily prayers to children during the Covid-19 pandemic. The research method used is qualitative. Data collection techniques are observation, interviews, and documentation. Triangulation data analysis. Research result; 1) invite children to pray as early as possible, 2) remind children at prayer times, 3) provide an understanding of the law of prayer. Appreciation is given by parents if the child prays on time. Warnings and guidance are applied if the child finds it difficult to pray on time. In addition to coaching and guidance, the application of the five prayers discipline also utilizes image media and visual audio. Manage playtime, study time, sleep time and prayer time
Visionary Leadership of The Principal in The Implementation of Character Education at SMA Plus PGRI Cibinong Bogor Regency
Authors: Suhifatullah M I
Published: May 2022

Character education in schools is a severe problem, so it is necessary to find its root and solution. Various policies and formulations of character education have been made by the government and implemented in each school, but so far have not shown the expected results. Different deviations in student behavior at each level of education are still found, such as brawls between students, promiscuity and immorality, drug abuse, and other irresponsible behavior. This study aims to reveal data related to the visionary leadership of the principal as a driver of the character education system at SMA PLUS PGRI Cibinong, Bogor Regency. This research uses a descriptive qualitative method with data collection tools using interview, observation, and documentation studies.Meanwhile, the triangulation technique was used to test the validity of the data. The results showed that the principal, with his visionary leadership, had been able to mobilize all components of the character education system at SMA PLUS PGRI Cibinong, Bogor Regency, to create a conducive school environment for the implementation of student character education. The success of this school has been recognized nationally so that it becomes a reference school or a comparative study destination for schools in Indonesia in the implementation of character education.
К оценке фармакотерапевтической эффективности циклоартановых гликозидов в сравнении с ловастатином у кроликов с экспериментальным атеросклерозом
Authors: Сыров Владимир Николаевич , Кайпназаров Т. Н. , Царук Анастасия Викторовна , Исламова Жаннат Икрамовна , Шахмурова Гульнара Абдуллаевна , Эгамова Ф. Р. , Рамазанов Н. Ш. , Хушбактова Зайнаб Абдурахмановна
Published: May 2022

Циклоартановые гликозиды циклокарпозид и циклосиверсиозид F препятствуют увеличению содержания в сыворотке крови у кроликов с атеросклерозом холестерина, триглицеридов и суммарной фракции пре-β- и β-липопротеидов. Повышают отношение α-холестерина к общему холестерину, снижают расчетный коэффициент атерогенности и отношение суммарной фракции пре-β- и β-липопротеидов к α-холестерину. Кроме этого, циклоартановые гликозиды восстанавливают сниженную при атеросклерозе у кроликов активность антиоксидантной и NO-эргической систем в сердечной мышце. По антиатеросклеротическому действию исследуемые циклоартановые гликозиды (особенно циклокарпозид) уступают препарату из группы статинов — ловастатину. По влиянию на антиоксидантную и NO-эргическую системы они имеют перед ловастатином определенные преимущества.
Исследование мембранотропных свойств ацилированных пептидных производных дофамина и серотонина при использовании метода PAMPA
Authors: Шевченко Валерий Павлович , Андреева Людмила Александровна , Шевченко Константин Валерьевич , Нагаев Игорь Юлианович , Мясоедов Николай Федорович
Published: May 2022

Синтезированы ацилированные лауриновой (LA) и олеиновой (OA) кислотой пептидные производные дофамина (DA) и серотонина (5-HT, 5-гидрокситриптамин) LA-Gly-Pro-DA, LA-Gly-Pro-5-HT, OA-Gly-Pro-DA, OA-Gly-Pro-5-HT. Разработан масс-спектрометрический метод оценки содержания производных дофамина и серотонина в фосфатно-солевом буфере (PBS Am-E404-100, pH 7,4). Показана возможность проникновения этих соединений через искусственные мембраны. Использование смеси этих соединений позволило создать ситуацию, при которой диффузия молекул производных дофамина и серотонина через мембрану происходила в результате конкурентных взаимодействий, что позволило достоверно определить, какие соединения в этой смеси легче проникали через искусственные мембраны. Оценку сравнительной проницаемость гематоэнцефалического барьера (ГЭБ) проводили методом PAMPA (parallel artificial membrane permeability assay). Установлено, что наиболее перспективными в плане преодоления ГЭБ являются ацилированные лауриновой кислотой производные — LA-Gly-Pro-5-HT и LA-Gly-Pro-DA.
Разработка методики количественного определения суммы флавоноидов в траве бархатцев отклоненных
Authors: Куркина Анна Владимировна , Савельева Анна Евгеньевна , Куркин Владимир Александрович
Published: May 2022

Бархатцы отклонённые (Tagetes patula L.) являются ценным источником биологически активных соединений, в том числе флавоноидов. Цель настоящего исследования является разработка методики количественного определения суммы флавоноидов в надземной части бархатцев отклоненных, заготовленной после сбора цветков. В результате проведенного исследования разработана методика количественного определения суммы флавоноидов в траве бархатцев отклоненных методом дифференциальной спектрофотометрии с использованием стандартного образца рутина при аналитической длине волны 412 нм. Определено, что содержание суммы флавоноидов в исследуемых образцах травы бархатцев отклоненных варьирует от 1,68 ± 0,05 % до 2,94 ± 0,05 % (в пересчете на рутин). Ошибка единичного определения содержания суммы флавоноидов в траве бархатцев отклоненных с доверительной вероятностью 95 % составляет ± 3,86 %.
Синтез ацетоаминофена на природном H-клиноптилолите
Authors: Торосян Гагик Оганесович , Есаян П. А. , Алексанян Г. О.
Published: May 2022

Статья посвящена синтезу п-ацетиламинофенола (ацетоаминофен, парацетамол), который обладает анальгезирующим действием и является составной частью ряда лекарственных препаратов. Показано, что ацилирование адсорбированного из водных растворов п-аминофенола на цеолите — клиноптилолите в H-форме позволяет получать ацетоаминофен в наиболее простых, экономически выгодных и практически более удобных условиях, приближая процесс синтеза к разрешению задач зеленой химии. Такой метод также позволит утилизировать адсорбированный из водного раствора аминофенол.
Um percurso pela história da probabilidade
Authors: Vasconcelos Veraciv Brabo de , Vasconcelos Gabriel Brabo de , Chaquiam Miguel
Published: May 2022

Neste artigo apresentamos um recorte da história da probabilidade, embasado nas ideias de autores que defendem a história da matemática no ensino de matemática, como Iran Abreu Mendes e Miguel Chaquiam, referenciados por autores como Boyer (1974), Eves (2011), em trabalhos publicados como, teses, dissertações, artigos científicos e em documentos oficiais. Para organizar materiais para sala de aula nos orientamos no diagrama metodológico, de acordo com a proposta de Chaquiam (2016; 2017; 2020), ao propor a elaboração de um texto para ser utilizado em sala de aula, como recurso didático, mostrando no contexto da história da Matemática a origem e a evolução, concomitantemente com as estratégias de ensino da teoria da probabilidade, que levam a refletir e verificar a necessidade de responder a seguinte problemática de pesquisa: Que recortes históricos podem ser elaborados a partir de uma história da probabilidade, segundo Chaquiam (2020), para uso em sala de aula? Desta questão elegemos o objetivo geral que é: Elaborar recortes históricos a partir de uma história da probabilidade para uso em sala de aula. Como a pesquisa está em andamento, temos como resultado, orientações sobre a relevância desta pesquisa, sobre os recortes da história da probabilidade e a necessidade de ampliação deste tema para proporcionar aos pesquisadores uma base sólida da importância que a história da matemática pode proporcionar ao ensino de matemática.
A Matemática nos primórdios da Escola de Minas de Ouro Preto: uma visão geral
Authors: Pereira Vinicius Mendes Couto
Published: May 2022

O processo de estabelecimento de uma comunidade matemática nacional tem sido um relevante problema dentro da historiografia da Matemática. Em particular, pesquisas têm apresentado um panorama acerca do surgimento e formação de uma comunidade matemática brasileira. Nesse quadro, verifica-se o predomínio exclusivo, por pelo menos um século, do ensino de Matemática Superior na formação de Engenheiros. Em particular, no século XIX, a Academia Real Militar e as instituições que a sucederam desempenharam esse papel com primazia. Por outro lado, nem sempre, a Escola de Minas de Ouro Preto, fundada em 1876, tem sido considerada como uma instituição que ministrou ensino de Matemática Superior. Nesse sentido, este artigo busca apresentar uma visão geral sobre a matemática desenvolvida na Escola de Minas de Ouro Preto, e investigar acerca da existência de professores de Matemática e de ensino de Matemática Superior nesta Instituição. Nessa linha, a pesquisa revela não somente a existência de professores de Matemática e de ensino de Matemática Superior, mas um certo protagonismo na produção científica e de determinadores atores neste contexto.
ITINERÁRIO DIAGNÓSTICO TERAPÊUTICO DE FAMILIARES E PESSOAS COM DOENÇA ONCOLÓGICA
Authors: Alexandrino Arthur , Araújo Bruno Gonçalo Souza de , Neto Olavo Maurício de Souza , Brito Débora Thaise Freires de , Agra Glenda , Costa Marta Miriam Lopes
Published: May 2022

O objetivo foi investigar o itinerário diagnóstico e terapêutico percorrido pelos familiares e pessoas com doença oncológica. Trata-se de um estudo qualitativo, desenvolvido em um hospital filantrópico de João Pessoa-PB. Foram construídas as seguintes categorias: Categoria 1 – Reconhecendo os sinais e sintomas antes do diagnóstico; Categoria 2 – do diagnóstico ao início da terapêutica: caminhos vivenciados pelos pacientes; Categoria 3 – Itinerário terapêutico dos pacientes, que foi dividida em Subcategoria 1 – Sintomatologia durante o tratamento e Subcategoria 2 – Dificuldades enfrentadas pelos pacientes durante a terapêutica proposta e a Categoria 4 – Desafios enfrentados pelos familiares. É importante compreender o contexto em que o processo de adoecimento é vivenciado e o tempo em que as etapas do itinerário diagnóstico e terapêutico são desenvolvidas, a fim de prestar uma melhor assistência.
‘Poco a poco’
Authors: Martínez Martín Abel Fernando , Otalora Cascante Andres Ricardo
Published: May 2022

Los orígenes de la iglesia de la Compañía de Jesús de Tunja se remontan cuatro siglos atrás, a inicios del siglo XVII, cuando el templo nace en el interior una casa a media cuadra de la plaza mayor, adquirida por los jesuitas para fundar su colegio-noviciado, que fue creciendo poco a poco con muchas dificultades. La fachada solo logra salir a la calle a mediados del siglo XVIII. Tras la expulsión de los jesuitas, inicia la dispersión de los bienes muebles y el cambio de usos del templo, que se convertirá en convento-hospital y colegio-universidad republicano. En los años setenta del siglo XX se produce una intervención con fines turísticos que desfiguró su espacialidad y la convirtió en sala de conciertos. En los años ochenta, una restauración corrigió parte de la intervención exterior y consolidó la cubierta de la antigua iglesia de la Compañía de Jesús, hoy usada como templo.
Gap in STEM Education: Why is there a decline in women participation?
Authors: Kenneth Anthony
Published: May 2022

A steady Gender gap is observed with the number of students enrolled in STEM (Science, Technology, Engineering, and Mathematics) fields in higher education and universities. The underrepresentation of women in the field of STEM is world-wide. Numerous studies have contemplated different factors for this gap and studies on interests showing, that women's career decisions are often influenced by their interest which is inclined towards working ‘with people’ and deviates them from STEM. Men prefer to work with ‘material and gadgets’ which interests more men towards STEM. Increment in “enterprising and artistic interests” among the women, less awareness on the career and study opportunities, lesser female mentors, the duration to become an expert in STEM, lesser encouragement from the opposite sex, has an impact on the number of females in STEM. The gap was more prominent in egalitarian countries and termed as the “education gender-equality paradox”. The difference in early childhood spatial ability can also contribute to the emergence of gender differences in mathematics and science later. This article also suggests more research into making STEM attractive for both genders, providing early education that provides makes STEM attractive for both genders.
Analisis Cluster Untuk Pengelompokkan Prestasi Mahasiswa Angkatan 2013 Fakultas MIPA Universitas Islam Madura
Authors: Zaifullah Zaifullah , Yulianto Tony
Published: May 2022

Student achievement is a person's mastery of certain knowledge or skills in a course, which is obtained from test scores or numbers given by the lecturer. Many factors affect student achievement, including parents' income, pocket money, distance to campus, length of time studying, student side jobs, and the existence of learning aids. Therefore, a research will be conducted using cluster analysis for grouping student achievement in the hope of mapping students so that it is easier for lecturers to teach students. In this case, four cluster analysis methods are used, namely single linkage, complete linkage, average linkage and k-means. Where the best grouping is obtained with the icdrate, namely average linkage. The results of the average linkage method obtained that the two groups were the lowest of the other five groups who had to get more guidance from other groups.
Strategi Pemasaran Produk Sepeda Motor Honda Menggunakan Fuzzy Teori Permainan
Authors: Adabawiyah Robiatul
Published: May 2022

Honda motorcycles are a means of transportation that are inexpensive and more flexible than other means of transportation. Honda motorcycles themselves are the choice of consumers, because of their fuel economy, smooth engine sound, and good quality spare parts. Intense market competition has become a necessity in the business world (business). Companies must think of optimal marketing strategies and concepts based on consumer ratings of Honda motorcycles. The uncertainty of consumer assessment of the products used is interpreted using fuzzy. Determination of marketing strategy is done by using game theory. So that the most optimal strategy in the game is won by the exhibition promotion strategy.
Pengenalan Kepribadian Seseorang Melalui Bentuk Tulisan Tangan Menggunakan Metode Radial Basis Function Neural Network (RBFNN)
Authors: Magfiroh Alfin
Published: May 2022

Humans are created with a variety of different characters and characters, so that the personality that is formed is very diverse according to the character and character of each person. With a variety of personalities, it appears that there are differences in quality and quantity between humans from one another in the view of society. There are various ways to get to know a person's personality, one of which is through handwriting with specific letters of the alphabet. In this study, handwriting is limited to the letter 't' only and has been generated from 26 images of 't' training which were previously processed using the PCA method, there are 10 images according to the type 't' 1 and 16 images according to the type 't ' 2nd and no image matches the 3rd 't' type.
Optimalisasi Produksi Pada Industri Tahu Menggunakan Model Linear Programming
Authors: Faruk Ainul
Published: May 2022

Tofu is a source of nutrition that is affordable by all people. In addition, processed soybean-based foods are also very popular with the wider community. As for tofu, there are many problems in the problem, one of which is the problem of maximizing the process of making processed soybeans to achieve maximum profit. Therefore, this research was conducted using a linear programming model using the simplex method so that the optimal results obtained from this study were tofu as many as 241 boards and tempeh 250 seeds with a maximum profit of Rp. 1,577,770.
Kaskat Sistemler için Genetik Algoritma ile Optimize Edilmiş Gelişmiş Kaskat Kontrolör Tasarımı ve Deneysel Uygulaması
Authors: NALBANTOĞLU Mustafa , KAYA İbrahim
Published: May 2022

Tek döngülü geleneksel kontrolör, kontrol edilen değişken ayar noktasından sapmadıkça bozulmalar için herhangi bir düzeltici eylemi başlatmaz. Böyle bir durumda, özellikle bozulmaları olan bir kademeli sistemde bu kontrol sisteminin performansını iyileştirmek için kademeli bir kontrol stratejisi kullanılabilir. Klasik kademeli kontrol yapısında, hem iç hem de dış döngüde Oransal-İntegral-Türev (PID) tipi kontrolörler kullanılır. Bununla birlikte, PID kontrolörleri, açık döngü kararsız süreçler ve transfer fonksiyonlarında bir integratör bulunan süreçler için iyi performans göstermeyebilir. Bazı durumlarda, kademeli kontroldeki dış döngü transfer fonksiyonu açık döngü kararsız olabilir veya bir integratör içerebilir. Bu nedenle, kontrol edilen sisteme ilişkin kapalı döngü yanıtı tatmin edici olmayabilmektedir. Bu çalışmada, dış döngüde bir PI-PD kontrolörünün kullanıldığı geliştirilmiş bir kademeli kontrol yapısı önerilmiştir. Önerilen geliştirilmiş kademeli kontrol şemasında kontrolörlerin optimal parametrelerinin ayarlanması, Genetik Algoritma (GA) kullanılarak eş zamanlı olarak elde edilmiştir. Önerilen geliştirilmiş kademeli kontrol yapısının literatürde önerilen bazı kademeli kontrol şemalarına göre üstünlüğü simülasyon örnekleri ile gösterilmiştir. Ayrıca, önerilen geliştirilmiş kademeli kontrol yapısının geçerliliğini göstermek için DIGIAC 1750 süreç kontrol seti üzerinde gerçek zamanlı uygulama gerçekleştirilmiştir.
The haves and have-nots: Glycine, valine and arginine in heart disease and cancer
Authors: Zhang Xiaoxiao , Ouyang Jess Lan , Peng Jingli , Fu Min , Wang Yuchuan , Liu Qiuyun
Published: May 2022

KRAS G12, BRAF V600, IDH1 R132 are the 3 most frequent somatic mutation sites across 41 cancer types in a previous survey, yet glycine plus valine is overrepresented in heart disease, Alzheimer’s disease as well as SARS and SARS-CoV-2 proteins. This finding suggests that these amino acids could play contradictory roles in different major human diseases. Valine and glycine have long carbonyl bond lengths, allowing potent secondary chemical bonding of carbonyl oxygen to cations, particularly divalent cations. Arginine potentially possesses coordination bond with calcium besides attracting anions such as oxalate. The formation of insoluble and stiff calcium salts, for instance calcium oxalate, is stressful to the cells. This important phenomenon has not been extensively explored in the studies of human disorders except renal stones. The aforementioned insight highlights the need for different intervention measures for heart disease and cancer, two major age-related diseases.
Resume Kebijakan Moneter Dalam Perspektif Islam
Authors: Khaerat Muhammad Emir
Published: May 2022

Kebijakan Moneter adalah kebijakan pemerintah untuk memperbaiki keadaan perekonomian melalui pengaturan jumlah uang beredar. Untuk mengatasi krisis ekonomi yang hingga kini masih terus berlangsung, disamping harus menata sektor riil, yang tidak kalah penting adalah meluruskan kembali sejumlah kekeliruan pandangan di seputar masalah uang.
Cointegration between Stock Market and Economic Growth: Evidence From Nepal
Authors: Rana Surya Bahadur
Published: May 2022

This paper examines the linkage between stock market development and economic growth in the context of Nepal using 33 annual observations from Mid-July 1988 to 2020 on economic and financial time series of real GDP, market capitalization and annual turnover. The study employs Engle-Granger(1987) and Johansen’s (1988) cointegration test to examine the cointegration between economic growth proxied by log of real GDP and stock market development indicators, namely stock market size and liquidity, proxied by log of market capitalization and log of annual turnover, respectively. The results of cointegration show that both stock market size and liquidity can predict economic growth in Nepal. The results of cointegration test from both Engle-Granger procedures and Johansen’s method suggests that economic growth is cointegrated with both stock market size and stock market liquidity, and hence they are interrelated with each other in the long run. The basic implication of study finding is that both stock market size and liquidity significantly predict the economic growth in Nepal over the sample period and hence there is a need for promoting secondary market trading both in terms of size and liquidity.
Trade Liberalization in Nepal: Analysis of Its Impact
Authors: Kharel Khom Raj , Upadhyay Yadav Mani , Adhikari Dipak Bahadur
Published: May 2022

The objective of this study is to examine the impact of trade liberalization on Nepalese economy over the period 1990-2018. As per studies, trade liberalization increases the areas and size of foreign trade.  Nepal has introduced the economic and trade liberalization policy in mid-1980s and started to liberalize its trade and investment after 1990s. After the adoption of economic liberalization, the flow of foreign trade, economic growth of Nepal has been significantly increasing. The impact of trade liberalization on economy is measured in terms of economic growth, trade tax, industrial GDP and ratio of trade tax to total size of trade of Nepal by applying simple and multiple regression models. In Simple regression model, four equations show a positive correlation between INGDP and import, export, total trade, EOI inflation rate.
Solid-Liquid Equilibrium and Phase Diagram of Organic System Forming Simple Eutectic
Authors: Sharma Krishna Prasad , Neupane Umesh , Karki Bishal , Aryal Pradeep
Published: May 2022

The study of phase diagram guided with solid-liquid equilibrium (SLE) data at different molar composition in two component systems serve as a basic roadmap for the material synthesis, and also provide in-depth study of physicochemical and thermochemical properties of synthesized materials. The solid-liquid equilibrium data of binary organic system, acetanilide – acetamide (ACN-ACT) is determined by thaw melt method. The system exhibits simple eutectic type phase diagram at 0.20 molar composition of ACN with congruent melting temperature 52oC.
Effect of plastic pyrolysis oil and its blends with diesel on Cetane Index
Authors: Karn Rupesh Lal , Aryal Suman , Neupane Barsha ` , Bhattarai Kushal , Palikhel Laxman
Published: May 2022

Availability and higher gasoline price have attracted the attention of researchers towards alternative fuels. Plastic is produced from the byproduct of gasoline products, which possesses a higher possibility of recycling the waste plastic as an alternative fuel. Research conducted on plastic fuel shows that a diesel engine can run with 100% plastic oil. The present work is focused on the effect of distilled plastic oil on the cetane index as the cetane index is a major fuel property of diesel that affects the ignition quality and exhaust emissions of the engine. For the measurement of the cetane index, two standards are followed and they are ASTM D4737 and ASTM D976. It is found that Crude plastic oil produced from thermal pyrolysis of waste plastic possesses a wide variety of hydrocarbon i.e. lower to higher hydrocarbon. From the fractional distillation of crude plastic oil at three temperature ranges 200◦C, 290◦C and up to the final boiling point, it gave petrol grade oil and diesel grade oil (both low and high grade). Also, it was found that the recovery of distilled high-grade plastic oil is higher than other distilled crude plastic oil. Along with this, crude plastic oil, as well as high-grade plastic oil, have a higher cetane index than the diesel available in the market. Similarly, blending diesel with high-grade plastic oil up to 20% by volume and with low-grade plastic oil up to 10% by volume increases the cetane index of fuel.