bluuebunny/crossref_metadata_2025 huggingface dataset:
Possibility of pharmacological correction of NMDA-induced retinal excitotoxicity by 3-hydroxypyridine derivatives
Authors:   Belgorod State University, Solovev N.V.
Published: June 2023

Relevance. Glaucoma is the leading cause of blindness worldwide. Among all pathological mechanisms, a special role is assigned to glutamate excitotoxicity, which accompanies a number of pathological conditions of the retina. The aim of this work was to study the pharmacological activity of compounds of 3-hydroxypyridine derivatives in a model of NMDA-induced retinal degeneration. Material and methods. The introduction of the compounds was carried out in the prophylactic mode of administration. 7 days after the model, ophthalmoscopic changes in the fundus and the level of microcirculation were assessed. Research results. According to the results of the study, it was found that the compound LHT 6-20 had the highest activity. Compound LHT 6-20 at a dose of 25.5 mg/ kg in a model of neurodegenerative retinal damage induced by intravitreal administration of NMDA in rats with a prophylactic administration regimen provides an improvement in the fundus picture by 15.4%, relative to the group with a pathology model, which has a statistically a significant difference (p < 0.05), an increase in the level of microcirculation in the retina by 14.1% relative to the group with the model, while the indicator has a statistically significant difference from the group with pathology (p < 0.05), but does not differ from the reference drug (p > 0.05). Keywords: derivatives of 3-hydroxypyridine, NMDA, excitotoxicity, retina, rats, the level of microcirculation, ophthalmoscopy
The prevalence of radiation-induced ophthalmopathology personnel use of nuclear energy
Authors:   Siberian State Medical University, Tomsk, Russian Federation, Takhauova L.R. ,   Seversk Biophysical Research Center of the Center of the Federal Medical and Biological Agency, Seversk, Russian Federation, Krivosheina O.I. ,   Siberian State Medical University, Tomsk, Russian Federation, Takhauov A.R. ,   Seversk Biophysical Research Center of the Center of the Federal Medical and Biological Agency, Seversk, Russian Federation
Published: June 2023

Perpose. A retrospective analysis of the morbidity rates of the organ of vision in the personnel of the facility using ionizing radiation of energy under long-term technogenic external exposure was carried out. Material and method. The medical records of 3,795 employees were analyzed. The personnel in the framework of this study was divided into 2 groups: the main one – 2,546 employees of the main production; comparison – 1,249 employees of auxiliary production. Results. As the age of the staff increases, there is an increase in the incidence of ophthalmopathology in both groups. The level of morbidity with pathology of the organ of vision in the main group aged 30 to 70 years at the time of diagnosis is statistically significantly higher than that in the comparison group. At the same time, a high prevalence of diseases of the ocular surface was noted: in the main group, conjunctivitis is most common, in the comparison group – diseases of the eyelids. Keywords: ionizing radiation, long-term technogenic external exposure, ocular surface, morbidity
Эволюция образа женщины в популярной русской и советской песне
Authors: Zaynuldinov Tiarenkov Andrey
Published: June 2023

Настоящая статья посвящена исследованию эволюции образа женщины в популярных русских и советских песнях. Автор рассматривает русские популярные песни на протяжении более 100 лет истории, подвергая анализу разнообразные жанры: народной, цыганской, эстрадной, а также русского романса. Особое внимание уделяется советскому периоду российской истории, представлены песни 20–30 годов ХХ века, песни военных лет, послевоенной советской эстрады. Подтверждена гипотеза, что образ русской женщины обусловлен временными историческими обстоятельствами и эволюционировал в сторону более свободной современной женщины вне социальных стереотипов и патриархальных предрассудков. Образы женщин в фольклоре и русском романсе остаются неизменными, это идеализированная возлюбленная. Эта тенденция нарушается в советское время, где появляется новая профессиональная сфера деятельности женщины, что связано с эмансипацией. Образ женщины в эстрадной песне становится многообразнее, объемнее, это уже не только возлюбленная, молодая девушка, но и любящая женщина, мать.
Antibody-PROTAC Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 (RIPK2) in HER+ Cell Lines
Authors: Chan Karina , Soundarya Sathyamurthi Preethi , Queisser Markus , Mullin Michael , Shrives Harry , Coe Diane , Burley Glenn
Published: June 2023

Proteolysis targeting chimeras (PROTACs) are a family of heterobifunctional molecules that are now realising their promise as a therapeutic strategy for targeted protein degradation. However, one limitation of existing designs is the lack of cell-selective targeting of the protein degrading payload. This manuscript reports a cell-targeted approach to degrade receptor-interacting serine/threonine-protein kinase 2 (RIPK2) in HER2+ cell lines. An antibody-PROTAC conjugate is prepared containing a protease cleavable linkage between the antibody and the corresponding degrader. Potent RIPK2 degradation is observed in HER2+ cell lines, whereas an equivalent anti-IL4 antibody-PROTAC conjugate shows no degradation at therapeutically relevant concentrations. No RIPK2 degradation was observed in HER2- cell lines for both bioconjugates. This work demonstrates the potential for cell-selective delivery of PROTAC scaffolds by engaging with signature extracellular proteins expressed on the surface of particular cell types.
Enzymatically catalyzed furan-based copolyesters containing dilinoleic diol as a building block
Authors: Sokołowska Martyna , Nowak-Grzebyta Jagoda , Stachowska Ewa , Miądlicki Piotr , Zdanowicz Magdalena , Michalkiewicz Beata , El Fray Miroslawa
Published: June 2023

An environmentally friendly method for creating sustainable alternatives to traditional aromatic-aliphatic polyesters is a valuable step towards resource-efficiency optimization. A library of furan-based block copolymers was synthesized via temperature-varied two-step polycondensation reaction in diphenyl ether using Candida antarctica lipase B (CAL-B) as biocatalyst where dimethyl 2,5-furandicarboxylate (DMFDCA), α,ω-aliphatic linear diols (α,ω-ALD), and bio-based dilinoleic diol (DLD) were used as the starting materials. Nuclear magnetic spectroscopy (1H and 13C NMR), Fourier transform spectroscopy (FTIR) and size exclusion chromatography (SEC) were used to analyze the resulting copolymers. Additionally, crystallization behavior and thermal properties were studied using X-ray diffraction (XRD), digital holographic microscopy (DHM), and differential scanning microscopy (DSC). Finally, oxygen transmission rates (OTR) and dynamic mechanical analysis (DMTA) of furan-based copolyesters indicated their potential for medical packaging.
The lucigenin assay: measuring anion transport in lipid vesicles
Authors: Chvojka Matúš , Singh Anurag , Cataldo Alessio , Torres Huerta Aaron , Konopka Marcin , Šindelář Vladimír , Valkenier Hennie
Published: June 2023

Synthetic anion transporters are developed to transport anions across lipid membranes with the long-term perspective of biological applications. The lucigenin assay is a popular tool to study their transport of chloride and other anions in liposomes. It relies on the quenching of the fluorescence of encapsulated lucigenin by anions, which can be monitored by fluorescence spectroscopy. This article provides a tutorial introduction to the practical use and understanding of the lucigenin assay. It describes in detail how to use this assay to monitor chloride/nitrate antiport in liposomes, process and interpret the data, and solve common issues. Variations of the assay enabling the investigation of the transport of other anions and transport mechanisms are discussed. Furthermore, a zwitterionic analogue of lucigenin is demonstrated to have advantages for use in specific cases.
Introducing Materials Funnel 2.0 - hierarchical search in infinite chemical space
Authors: Ortega Ochoa Raul , Benediktsson Bardi , Jørgensen Peter Bjørn , Bhowmik Arghya
Published: June 2023

Inventing new ways of exploring the materials phase space accelerates functional materials discovery. For new breakthroughs materials, faster exploration of bigger phase spaces is a key goal. High throughput computational screening (HTCS) is widely used to quickly search for materials with the right functional property. In this article we redefine HTCS methods to combine deep learning and physics based model to explore much large chemical spaces than possible by pure physics driven HTCS. Deep generative models are used to autonomously create materials libraries with high likelihood of desired properties, inverting the design paradigm. Additionally machine learnt surrogates enable next layer of screening to prune the set further such as high quality quantum mechanical simulations can be performed. With organic photovoltaic (OPV) molecules as test bench, we show the power of this redesigned HTCS approach in inverse design OPV molecules with very limited computational expense.
Metal-free Catalytic Hydrogenolysis of Chlorosilanes into Hydrosilanes with “Inverse” Frustrated Lewis Pairs
Authors: Durin Gabriel , Berthet Jean-Claude , Thuéry Pierre , Nicolas Emmanuel , Cantat Thibault
Published: June 2023

The challenging metal-free catalytic hydrogenolysis of silyl chlorides to hydrosilanes is unlocked by using an inverse frustrated Lewis pair (FLP), combining a mild Lewis acid (Cy2BCl) and a strong phosphazene base (BTPP), in mild conditions (10 bar of H2, r.t.). In the presence of a stoichiometric amount of the base, the hydrosilanes R3SiH (R = Me, Et, Ph) are generated in moderate to high yields (up to 95%) from their chlorinated counterparts. A selective formation of the valuable difunctional monohydride Me2SiHCl is also obtained from Me2SiCl2. A mechanism is proposed based on stoichiometric experiments and DFT calculations; it highlights the key role of borohydride species, generated by the heterolytic splitting of H2.
Reductive Arylation of Nitroarenes with Chloroarenes: Reducing Conditions Enable New Reactivity from Palladium Catalysts
Authors: Akana-Schneider Brett , Weix Daniel
Published: June 2023

Palladium-catalyzed C–N bond forming reactions are a key tool in modern synthetic organic chemistry. Despite advances in catalyst design enabling the use of a variety of aryl (pseudo)halides, the neces-sary aniline coupling partner is often synthesized in a discrete reduc-tion step from a nitroarene. An ideal synthetic sequence would avoid the necessity of this step while maintaining the reliable reactivity of palladium catalysis. Herein we describe how reducing conditions enable new chemical steps and reactivity from well-studied palladium catalysts, resulting in a new, useful transformation: the reductive arylation of nitroarenes with chloroarenes to form diarylamines. Mechanistic experiments suggest that under reducing conditions, BrettPhos-palladium complexes catalyze the dual N-arylation of typi-cally inert azoarenes—generated via the in situ reduction of ni-troarenes—via two distinct mechanisms. Initial N-arylation proceeds via a novel association-reductive palladation sequence followed by reductive elimination to yield an intermediate 1,1,2-triarylhydrazine. Arylation of this intermediate by the same catalyst via a traditional amine arylation sequence forms a transient tetraarylhydrazine, un-locking reductive N–N bond cleavage to liberate the desired product. The resulting reaction allows for the synthesis of diarylamines bearing a variety of synthetically valuable functionalities and heteroaryl cores in high yield.
Bromide-Mediated Silane Oxidation: A Convenient and Practical Counter-Elecrode Process for Undivided Electrochemical Reductions
Authors: Avanthay Mickael , Goodrich Oliver , George Michael , Lennox Alastair
Published: June 2023

The counter-electrode process of an organic electrochemical reaction is integral for the success and sustainability of the process. Unlike for oxidation reactions, there is not a generally practical counter-electrode process for reduction reactions, especially for deep reductions that apply very negative potentials. Herein, we report the development of a bromide mediated silane oxidation counter-electrode process for electrochemical reduction reactions in undivided cells. It is found to be suitable for replacing either sacrificial anodes or the use of a divided cell in several reported reactions. These conditions are metal-free, use inexpensive reagents and a graphite anode, the by-products are reductively stable and readily removed, and the process is demonstrated on large scale in flow.
Hypoxia controls expression of kidney-pathogenicMUC1variants
Authors: Naas Stephanie , Krüger René , Knaup Karl Xaver , Naas Julia , Grampp Steffen , Schiffer Mario , Wiesener Michael , Schödel Johannes
Published: June 2023

The interplay between genetic and environmental factors influences the course of chronic kidney disease (CKD). In this context, genetic alterations in the kidney disease geneMUC1(Mucin1) predispose to the development of CKD. These variations comprise the polymorphism rs4072037, which alters splicing of MUC1 mRNA, the length of a region with variable number of tandem repeats (VNTR), and rare autosomal-dominant inherited dominant-negative mutations in or 5′ to the VNTR that causes autosomal dominant tubulointerstitial kidney disease (ADTKD-MUC1). As hypoxia plays a pivotal role in states of acute and chronic kidney injury, we explored the effects of hypoxia-inducible transcription factors (HIF) on the expression ofMUC1and its pathogenic variants in isolated primary human renal tubular cells. We defined a HIF-binding DNA regulatory element in the promoter-proximal region ofMUC1from which hypoxia or treatment with HIF stabilizers, which were recently approved for an anti-anemic therapy in CKD patients, increased levels of wild-typeMUC1and the disease-associated variants. Thus, application of these compounds might exert unfavorable effects in patients carryingMUC1risk variants.
EMPAT PILAR KEHIDUPAN BERBANGSA DAN BERNEGARA DALAM PARADIGMA PENDIDIKAN ISLAM
Authors: Bakar Usman Abu
Published: June 2023

In todayâ€™s world, Islamic education is facing an alarming dilemma. On one hand, there is a need to modernize the concept and practice of Islamic education. On the other hand, it cannot halt its pace for global competition is a never ending process. Its current challenge is to continuously improve its quality in many fields one of which is to respond to global development. One nationâ€™s incapability to respond to global changes could lead to ideological crisisÂ  endangering the identity of its citizens. Tauhid-oriented education is considered to excel in dealing with global phenomena and to produce socially pious individuals. In addition, it is mandatory for a state as an education system to develop its citizensâ€™ characters reserving the nationâ€™s spirit. The four pillars discussed in the article are considered one alternative door to Indonesiaâ€™s revitalization that focuses on human resource development, both on being a good citizen and on modernizing Islamic education
Strengthen the Role of Indonesia in the Constellation of Asean Economic Community Through the Knowledge Based Economy
Authors: Muhlisin Muhlisin
Published: June 2023

The purpose of this paper is to map the role of Indonesia in facing the competition in the era of asean economic community. This idea motivated by a certainty that as a great nation, Indonesia should have a variety of strategies in playing its role to become a nation that has a significant role.The author seeks to explore the roles that can be played by Indonesia in the enforceability of the ASEAN economic community. However, theimplementation of Asean economic community has an implication on the education system in Indonesia. It takes a variety of strategies that should be pursued by the Indonesian government to exist in the competition arena of asean economic community. One of the strategies is to implement knowledge based economy in facing asean economic community. The way to apply it is through good quality of education system, at least the strategy reffers to 4 recommendations from Unesco to the fulfillment of 8 national education standards, because education as a strategic means to establish a characterless human resource. The availability of characterless generation would be one of Indonesiaâ€™s strengths and leverages to compete in the era ofAsean Economic Community.
Fitrah dan Kemanusiaan
Authors: Laksono Nur Idham
Published: June 2023

Penelitian ini bertujuan untuk menjelaskan bagaimana konsep fitrah yang kemudian dikaitkan dengan persoalan kemanusiaan diantaranya spiritualitas, epistemologi, kesatuan manusia dan struktur masyarakat. Jenis penelitian ini adalah penelitian pustaka. Metode yang peneliti gunakan adalah pengumpulan data dan pengolahan data. Dengan metode pengumpulan data, peneliti mengumpulkan data-data primeryang terkait dengan penelitian ini, baik yang terkait dengan tasawuf, epistemologi, politik, maupun filsafat. Dengan metode pengolahan data, peneliti melakukan penyaringan dan memilah data untuk disesuaikan dengan kebutuhan dalam penelitian ini. Untuk itu, peneliti menggunakan metode deskriptif, analisis data, dan interpretatif. Hasil penelitian menunjukkan bahwa konsepsi fitrah memiliki kemungkinan untuk dilihat dari berbagai sudut pandang. Teori fitrah sebenarnya dapat dicari relevansinya ke berbagai konteks, misalnya pendidikan, kebudayaan, ekonomi, filsafat dan lain-lain. Dari berbagai bidang tersebut, sebenarnya dapat dicakup dengan satu kata, yaitu kemanusiaan. Konsepsi fitrah berangkat dari asumsi bahwa pada dasarnya manusia memiliki kesamaanyang mendasar. Asumsi ini secara otomatis menolak setiap perlakuan tidak adil yang didasarkan pada perbedaan suku, agama, ras dan anatomi atau SARA.
Examining the Attitudes of Livestock Keepers within Animal Production Systems
Authors: Marmelo Carla Sofia
Published: June 2023

It has been proven that the interactions or relationships established between humans and animals in livestock production significantly affect both. Therefore, it is extremely important that the quality of these interactions be positive and reflect a genuine sense of caring on the part of the people who deal directly with the animals. This study draws on some of the most important publications on the subject from 1986 to 2022 found in article databases; presents the main concepts used to understand the subject; lists the main reasons for what can be considered mistreatment of animals in animal husbandry (negative behaviours); and proposes solutions based on the literature and the author's experience. The purpose of this article is to help a) shift the paradigm and prioritise the definition of a personal profile that should work with animals, rather than focusing exclusively on the technical training of animal caregivers or on the common definition of “stockperson"; b) propose an analytical solution that can be applied during the recruitment process; and c) serve as a basis for the most relevant literature on the subject, given the already large number of publications, and d) encourage mutual reflection. Doi: 10.28991/SciMedJ-2022-04-03-04 Full Text: PDF
Early photographic record of the Whooping Crane in the Battleford area, Saskatchewan
Authors: G. Sealy Spencer
Published: June 2023

Early photographic record of the Whooping Crane in the Battleford area, Saskatchewan
48th Annual Saskatchewan Christmas Mammal Count - 2020
Authors: Smith Alan
Published: June 2023

48th Annual Saskatchewan Christmas Mammal Count - 2020
Usaha Peningkatan Pendapatan Petani Melalui Penerapan Model Usahatani Ekologis Terpadu di Desa Mumbul Sari Kecamatan Bayan Lombok Utara NusaTenggara Barat
Authors: I Ketut Ngawit  , Jayaputra
Published: June 2023

Kontur lahan kering di Lombok Utara bergelombang  dan berbukit-bukit sehingga rawan erosi. Tipe iklim kering dengan bulan basah kurang dari 4 bulan tahun-1 dan sifat curah hujan yang eratic menyebabkan tanah lebih mudah tererosi sehingga penurunan produktivitas tanah semakin cepat. Tindakan yang tepat untuk mengatasi masalah tersebut adalah, pemanfaatan hubungan timbal balik antara tanaman dengan ternak sehingga terbentuk sistem usahatani ekologis terpadu. Sehubungan denga masalah tersebut maka telah dilakukan kegiatan pembinaan dan pendampingan yang bertujuan untuk meningkatkan pengetahuan dan keterampilan petani tentang pengelolaan model usahatani ekologis terpadu. Metode pendekatan yang digunakan adalah tindak partisipatif berupa pelatihan dan pendampingan secara langsung di lapang selama 8 bulan. Seluruh kegiatan berlangsung dengan tertib,aman dan lancar. Pengetahuan dan keterampilan petani  meningkat, sehingga semangat dan antusias mereka sangat tinggi memproduksi pupuk organik dari kotoran dan limbah kandang ternak sapi dan ayam petelur.  Pelaksanaan kaji tindak pengusahaan tanaman cabe rawit dan bawang merah pendapatan dan keuntungan yang diperoleh petani lebih tinggi dibandingkan dengan pengusahaan tanaman bayam, sawi, jagung manis dan kacang panjang.  Selain dapat memberikan keuntungan yang lebih tinggi, BC-ratio pengusahaan kedua jenis tanaman tersebut juga relatif lebih tinggi dibandingkan dengan pengusahaan komuditi lainnya, yaitu untuk tanaman cabe rawit 4,65 dan  bawang merah 2,50. Status kesuburan tanah dan pertumbuhan hasil tanaman tahunan meningkat bila pada tegakannya ditanami cabe rawit, bawang merah dan  kacang panjang.
Water quality aspects of ground water recharge modelling for sustained effluent irrigation
Authors:   Research Scholar, S SELVAKUMAR , M V RANGHASWAMI ,   Professor and head Department of Soil and Water conversation engineering, Tamil Nadu agricultural university, Coimbatore 641 003 India
Published: June 2023

Water quality aspect of ground water recharge modelling of M/S SIV Industries effluent irrigated farm in Coimbatore, Tamil Nadu, which is polluted due to the disposal of Viscose pulp plant effluents is carried out to know the impact of Sodium, Calcium and Magnesium in the ground water. The model was developed using the VISUAL MODFLOWpackage. At first, the flow modelling of the area is developed to find out the water table fluctuation and direction of ground water flow. The calculated values are retrieved in the mass transport package MT3D to find the concentration of Na, Ca and Mg in the ground water for various options. The result of this study indicated that the concentration values are on the increasing trend at all the observation points irrespective of options. However, the effect is minimized if diluted effluent irrigation was carried out. At 25per cent and 50 per cent dilution, the reduction in the rate of accumulation was observes as 2-3 times and 7 times respectively. The application of this developed model with VMF has created a new platform for the design of eco- friendly management of effluent irrigation schemes.
Energy input and output relationship in rice based cropping systems
Authors:   Sr.Scientist (Agronomt),IC AH Research Complex For Goa, Old Goa - 403402,Goa., B L MANJUNATH , C J ITNAL ,   Former Director of instruction(Agri.) and Emeritus Scientist (ICAR),University of Agricultural Sciences,Dharwad.
Published: June 2023

A field experiment was conducted in ICAR Research Complex at Goa, during 1999-2002 to study the energy input-output relationships of different rice based cropping systems with recycled manurial resources in a split-plot design with three replications. Among the cropping systems tried, rice- brinjal system received relatively higher energy input (23,135 MJ ha) that too from the non-renewable energy sources (14,909 MJ ha-1). However, the treatment could also yield substantially higher energy output (1,57,269 MJ ha). The use of recycled manures particularly paddy straw with mushroom spent substrate accounted for higher energy output although it recorded higher energy input (21,062 MJ ha). Rice-brinjal cropping system recorded better energy efficiency with additional input of energy in terms of irrigation which was mainly due to the higher productivity of the cropping system. In contrast, rice-sunnhemp and rice-fallow systems revealed lower energy input but ultimately their energy output was also lower.
Studies on the performance of arecanut (Areca catechu L.) seedlings to the nursery treatments
Authors:   Department of seed science and technology Tamil Nadu agricultural University Coimbatore-3, K RAJA , V PALANISAMY ,   Department of seed science and technology Tamil Nadu agricultural University Coimbatore-3, P SELVARAJU ,   Department of seed science and technology Tamil Nadu agricultural University Coimbatore-3
Published: June 2023

Studies on nursery treatments in arecanut showed that the seedlings performance differed significantly due to container size and pot mixture. In particular, the larger size container (25 x 15 cm) with pot mixture of soil sand+ Vesicular- Arbuscular Mycorrhizae (VAM) at 2:1:0.1 base produced vigourous seedlings followed by soil sand vermicompost at 2:1:1 mixture in nursery stage. It might be due to the better aeration in larger containers that facilitated easy root penetration and supply of adequate nutrients to the growing seedlings
Effect of spacing and fertilizer level on growth, seed yield and resultant seed quality in pea (Pisum sativum L.) cv. Bonneville
Authors:   Department of seed science and technology Tamil Nadu agricultural University Coimbatore-641003, V VAKESWARAN , A VIJAYAKUMAR ,   Department of seed science and technology Tamil Nadu agricultural University Coimbatore-641003
Published: June 2023

The treatments with four spacings (2.5, 5.0, 7.0 and 10 cm between plants and a uniform spacing of 40 cm between rows) and three levels of NPK fertilizers (80:60:50; 120:80:70 and 160:100:90 kg ha") were imposed on seed crop of pea (Pisum sativum L.) ev. Bonneville. Observations were made on days to first flowering, plant height, number of pods plant', pod yield plant', number of seeds pod", seed yield plant', shelling outturn and 100 seed weight. All the parameters were significantly influenced by spacings and fertilizer levels. With every increased level of NPK fertilizer and spacing, generally these characters showed favourble response. Germination potential, seedling growth, vigour index, dry matter production, electrical conductivity, protein content and free amino acids of the resultant seeds also have positive association with increased fertilizer levels and spacing.
VBN (Bg) 4 Black gram:A High yielding Yellow Mosaic Resistant Variety
Authors:   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, N MANIVANNAN , E MURUGAN ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, S JEBARAJ ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, P L VISWANATHAN ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, P SHANTHI ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, K MOHANA SUNDARAM ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, K SETHURAMAN ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai, G GAJENDRAN ,   National Pules Research Center, Vamban Colony- 622 303, Pudukottai
Published: June 2023

The black gram genotype VBG 55 is a hybrid derivative of CO 4 x PDU 102. It matures in 75-80 days. It has recorded an average seed yield of 782, 737 and 793 kg/ha during kharif, rabi and summer seasons respectively. It is an increased seed yield of 52.4, 67.8, 73.8 per cent over Vamban 1, 50.5, 34.3, 45.7 per cent over Vamban 2, 19.3, 20.2, 21.2 over Vamban 3, 78.6, 27.1, 43.8 over CO 5 and 31.4, 28.5, 28.7 over ADT 5 during kharif, rabi and summer seasons respectively. The culture VBG 55 has resistance to yellow mosaic virus disease and moderate resistance to powdery mildew. It is suited for sowing in all seasons and all districts of Tamil Nadu. Hence, the culture VBG 55 was accepted by State Variety Release Committee as VBN (Bg) 4 blackgram for commercial cultivation in Tamil Nadu during 2003.
Gene effects for certain Physical quality trauts and Grain yield in Rice
Authors:   Dept.Of Plant Breeding and Genetics College Of Agriculture, Rajendranagar Hyderabad 500 030, M SHREEDHAR , S VANISHREE ,   Dept.Of Plant Breeding and Genetics College Of Agriculture, Rajendranagar Hyderabad 500 030, M KULKARNI ,   Dept.Of Plant Breeding and Genetics College Of Agriculture, Rajendranagar Hyderabad 500 030, N GANESH ,   Dept.Of Plant Breeding and Genetics College Of Agriculture, Rajendranagar Hyderabad 500 030
Published: June 2023

Genetic analysis of certain physical quality traits of grain in four selected rice crosses indicated that milling recovery in Chandan/Sambamahsuri, head rice recovery in IR-64/Rasi and length/breadth ratio in all the crosses studied were under the control of additive gene action indicating the possibility of true breeding progenies for these parameters. However, the inheritance of traits like kernel length and breadth was influenced by both additive and non -additive type gene actions. Importance of all types of epistatic interactions were found to be governing the inheritance of grain yield. Postponement of selection of desirable segregants, to advanced generations could be suggested to exploit such complex genetic makeup.
Studies on combining ability analysis for quality traits in mungbean (Vigna radiata (L.) Wilczek)
Authors:   Department Of Plant Breeding and Genetics, Agricultural College and Research Institute Madurai 625 104, J ANBUMALARMATHI , P RANGASAMY ,   Department Of Plant Breeding and Genetics, Agricultural College and Research Institute Madurai 625 104, P YOGAMEENAKSHI ,   Department Of Plant Breeding and Genetics, Agricultural College and Research Institute Madurai 625 104
Published: June 2023

A study was conducted in mungbean (Vigna radiata (L.) Wilczek) to assess the combining ability of the parents as well as hybrids involving five lines and four testers crossed in line x tester model. The ratio of additive and dominance genetic variance (σA2: σD2) indicated that all the characters were found to be predominantly controlled by non additive gene action except solids lost which is governed by both additive and non additive gene action. The parents Vamban 2 and VGG 77 were found to be good general combiners for most of the quality traits and yield. The crosses ML 682 x Vamban 2, VGG 77 x KM 2 and VGG 80 x KM2 were identified as best specific combiners.
Stability of yield in relation to components traits in rice under rainfed low land condition
Authors:   Department of Plant Breeding Rajendra Agricultural university Bihar, Pusa - 848 125, KUMAR MANKESH , N K SINGH ,   Department of Plant Breeding Rajendra Agricultural university Bihar, Pusa - 848 125, KUMAR ANAND ,   Department of Plant Breeding Rajendra Agricultural university Bihar, Pusa - 848 125
Published: June 2023

Twenty rainfed low land rice genotypes were evaluated for their stability to grain yield and its component traits under three predictable environments created by changing the method of sowing and date of transplanting viz. direct sowing, normal transplanting and delayed transplanting. The pooled analysis of variance indicated that the mean differences, due to genotypes and genotype x environment interaction were significant indicating that the genotypes differ in their adaptability and stability. The pooled deviations were also significant for all the characters studied, suggested that these genotypes differed in their deviation from linearity. Most of the characters were influenced by non-linear components of G x E interaction, but magnitude of linear components were greater than non-linear types. On the basis of linear components characters, the genotypes RAU 1401-12-2, Satyam, Kishori expressed average response and relative stability under different environment for yield and yield components. Stability for grain yield and its components were also exhibited by the genotypes TTB 517-16-SBIR 70149- 33 and Satyam under favourable environment whereas, genotypes RAU 1305-6-3-2-3 had higher stability under poor environmental condition. The genotypes RAU 1401-12-2 and RAU 1314-3-3-3 were found to be stable under average environment for grain yield per plant. These genotypes are suitable for the rainfed low land condition which will also serve as good parents for the development of high yielding stable lines.
Spacing and weed management in transplanted basmati rice
Authors:   Department of Agronomy, College of Agricultue, Kerala Agricultural University, Vellayani 695 522, D JACOB , BETH ELIZA ,   Department of Agronomy, College of Agricultue, Kerala Agricultural University, Vellayani 695 522, K SYRIAC ,   Department of Agronomy, College of Agricultue, Kerala Agricultural University, Vellayani 695 522, R PUSHPAKUMARI ,   Department of Agronomy, College of Agricultue, Kerala Agricultural University, Vellayani 695 522
Published: June 2023

A field investigation was carried out at the Instructional farm, College of Agriculture, Vellayani during 2000-2001 to assess the effect of spacing and weed management practices on the performance of basmati rice. The treatments comprised of three spacings (15x15, 20x10 and 15x10 cm) and five weed control treatments (weed free check, unweeded control, hand weeding twice at 20 and 40 DAT, anilofos+2,4-DEE (readymix) 0.40+0.53 kg ha at 6 DAT supplemented with hand weeding at 20 DAT and anilofos+2,4-DEE (readymix) 0.40+0.53 kg ha' at 6 DAT supplemented with 2,4-D sodium salt 1 kg ha at 20 DAT). Grasses were the predominant weed species observed in the experimental field. Unchecked weed competition reduced grain yield to the tune of 46%. Herbicides were most effective in controlling the weeds. The results revealed that with 20x1 Ocm spacing (50 hills m2), pre-emergence application of anilofos+2,4-DEE (readymix) 0.40+0.53 kg ha supplemented with 2,4-D sodium salt 1 kg ha¹ could result in maximum grain yield and minimum weed competition.
Studies on milling outturn of paddy varietieis using rubber roll sheller
Authors:   Dept of Agrl.Processing, Tamilnadu Agrl.University,Coimbatore 641003,Tamilnadu, P RAJKUMAR , N VARADHARAJU ,   Dept of Agrl.Processing, Tamilnadu Agrl.University,Coimbatore 641003,Tamilnadu, V V SREENARAYANAN ,   Dept of Agrl.Processing, Tamilnadu Agrl.University,Coimbatore 641003,Tamilnadu
Published: June 2023

Paddy varieties namely ADT 41 and Basmati (extra long slender), CO 45 and ADT 38 (long slender), CO 43 and improved white ponni (medium slender) grains were dried under sun drying, shade drying and hot air drying at 30,40,50 and 60°C to the moisture content in the range of 12-14% w.b. They were shelled by using rubber roll sheller in order to increase the head rice recovery and milling outtura. The observations concluded that the time required for drying of extra long slender and long slender paddy varieties were comparatively lesser than medium slender varieties. The breakage was significantly higher in extra long and long slender varieties. From the milling results, it was found that the milling outturn and head rice recovery were significantly higher in shade dried paddy varieties. It was also observed that, as drying temperature was increased to 60°C the percentage of broken rice increased.
Assessment of physiochemical properties and bacteriological diversity of Otamiri river in Owerri eastern Nigeri
Authors: Ngozi Frank-Ogu  , Jude Nnama Ogbulie  , Sylvester Ifunanya Okorondu  , Campbell Akujobi
Published: June 2023

The physiochemical and bacteria diversity of Otamiri River was analyzed using standard microbiological methods. A total of seventy two (72) water and twenty four (24) sediment samples were collected. The routine plate count revealed that the number of heterotrophic bacteria present ranged from 1.00E+06 Cfu/ml to 9.70E+06 Cfu/ml, fecal coliform count 2.00E+05 Cfu/ml to 9.00E+06 Cfu/ml, Salmonella/Shigella count 3.50E+05 Cfu/ml to 1.52E+07 Cfu/ml, Staphylococcus count 2.00E+05 Cfu/ml to 1.79E+07 Cfu/ml, coliform count 3.50E+05 Cfu/ml to 4.59E+08 Cfu/ml, Vibrio count 1.50E+05 Cfu/ml to 3.52E+07 Cfu/ml. Anaerobic bacteria count ranged from 2.00E+05 Cfu/ml to 2.85E+06 Cfu/ml. The proportion of bacteria isolated from the samples showed that Alcaligens faecalis had the highest 68(94.44), 24(100), followed by Lysinibacillus macrolides 54(75), 21(87.5) while Lactobacillus spp had the least in water sample 6(8.33), Klebsiella aerogenes had the least in sediment 6(25). Among the physiochemical parameters analyzed in the river water and sediment samples had values above the recommended standard by WHO. The samples biophysical parameters did not meet the standard recommended by WHO for portable water. Therefore, to prevent potential health risks, those who use river water for domestic purposes must appropriately cleanse it before use. The government of the day should devise ways of disposing solid waste and effluent rather than channel same into the river and enact strict laws that will punish individual, agencies and firms that indulge in such in order to protect natural bodies of water from pollution. Statistical analysis using analysis of variance Posthoc = Tukey Alpha (0.05) indicated that the mean bacteria counts between the sampling stations differ significantly at the 0.05 level.
Associated risk factors of renal failure among patients attending Hemodialysis center at Al-Thwara Authority Hospital in IBB city, Yemen: A cross sectional study
Authors: Sadiq Kaid Al-Mohani  , Raafat Hamoud Abdo Al-Awadi  , Malak Essa Tajaldeen  , Aisha Mohammad Al-Mogammer  , Mosa Mohammed Al-Shaghdari  , Osama Foud Alshopi  , Basem Mohammed Al-Rymani
Published: June 2023

Background: Chronic renal failure is a major public health problem. Identifying individual’s risk factors are important to prevent infection of chronic renal failure. Objective: this study aimed to highlight the risk factors associated with chronic renal failure for patients attending hemodialysis center at Al-Thwara Authority Hospital in Ibb city, Yemen. Methods: the study is hospital-based cross sectional study. A total 100 patients collected randomly from hemodialysis centre at Al-Thwara Authority Hospital in Ibb, Yemen. Socio-demographic data, behavioral factors, medical history determined using a standardized questionnaire and analyzed by using IBM SPSS version 22 and Microsoft Excel. Results: the mean age of patients was 45.75 years, and most of them were in the range of 38-46 years. Males were 60% and 40% were females. Married subjects represented 86% and 38% of patients had primary education. Of the 100 respondents, 83% drink tap water, 86%Khat chewers, 75% consume soft drinks, 51% smokers, 48% had urinary tract infections and 30% urinary stones. Participants who used non-steroidal anti-inflammatory drugs represent 29% of the sample, 18% had heart disease and 14% of patients had pervious malaria infection. About 46% of the patients were hypertensive before their infection with renal failure, and 16% diabetics. There is association between gender of patients and heart diseases and malaria infection. Statistics correlation between age of patients and Khat chewing and smoking was estimated. Conclusion: this study suggests that, khat chewing, consumption of tap water, soft drinks and smoking increase the risk of chronic renal failure among Yemenis.
Analysis of the relationship between Good Corporate Governance (GCG) and financial performance before and after the covid 19 pandemic in pharmaceutical companies going public
Authors: Nurul Amalia Nandasari  , Ngatno  , Hari Susanta Nugraha
Published: June 2023

This study aims to analyze the effect of the board of commissioners, audit committee, and managerial ownership simultaneously and partially on the company's financial performance. The board of commissioners, audit committee, and managerial ownership are used as independent variables. The company's financial performance used in this study uses ROA (Return On Assets) as the dependent variable. The population in this study are pharmaceutical companies listed on the Indonesia Stock Exchange in 2012-2020. The sample amounted to 7 companies listed on the Indonesia Stock Exchange. The analysis method used to test the hypothesis is to use multiple linear regression analysis using the SPSS program. The results of this study indicate that partially the board of commissioners has no effect on the company's Return On Assets (ROA) financial performance; The audit committee affects the company's Return On Assets (ROA) financial performance; and Managerial ownership affects the company's Return On Assets (ROA) financial performance. Furthermore, simultaneously the board of commissioners, audit committee, and managerial ownership affect the financial performance of the company's Return On Assets (ROA).
Pengaruh Dampak Arus Kas Operasi dan Laba Terhadap Return Saham dan Dividen Kas Pada Perusahaan Industri Dasar & Kimia Yang Terdaftar Di Bursa Efek Indonesia
Authors: Munthe Sahmia , Indria Tika , Ilmiha Jalilah
Published: June 2023

The purpose of this study is to empirically examine the effect of operating cash flow and earnings on stock returns and cash dividends/cash dividends. This study uses the independent variables, namely operating cash flow and profit, and the dependent variable is stock returns and cash dividends. The research sample was taken from basic chemical industrial companies listed on the Indonesian stock exchange. Sampling was done by using purposive sampling method. The data collected is secondary data from the official website of the Indonesia Stock Exchange and the company's annual financial reports on their respective official websites. The data analysis method used is the classical assumption test consisting of normality test, multicollinearity test, and heteroscedasticity test. Multiple linear regression test, partial and simultaneous hypothesis testing, and coefficient of determination test. The results of this study indicate that partially operating cash flow has no significant effect on stock returns and cash dividends, and earnings have a significant effect on stock returns and cash dividends. Meanwhile, simultaneously operating cash flow and significant profit on stock returns and cash dividends.A B S T R A C T The purpose of this study is to empirically examine the effect of operating cash flow and earnings on stock returns and cash dividends/cash dividends. This study uses the independent variables, namely operating cash flow and profit, and the dependent variable is stock returns and cash dividends. The research sample was taken from basic chemical industrial companies listed on the Indonesian stock exchange. Sampling was done by using purposive sampling method. The data collected is secondary data from the official website of the Indonesia Stock Exchange and the company's annual financial reports on their respective official websites. The data analysis method used is the classical assumption test consisting of normality test, multicollinearity test, and heteroscedasticity test. Multiple linear regression test, partial and simultaneous hypothesis testing, and coefficient of determination test. The results of this study indicate that partially operating cash flow has no significant effect on stock returns and cash dividends, and earnings have a significant effect on stock returns and cash dividends. Meanwhile, simultaneously operating cash flow and significant profit on stock returns and cash dividends.
Pengarauh Kebijakan Deviden Kebijakan Hutang dan Profitabilitas terhadap Ukuran Perusahaan Sektor dagang yang Terdaftar di Bursa Efek Indonesia
Authors: Marpaung Irwan Taufik , Simbolon Ramadona , Andri Shofwan , Elviani Sri
Published: June 2023

Study aims to provide empirical evidence regarding dividend policy, policy, and profitability in predicting firm value by testing each ble. using the rupiah currency unit in financial reporting, the company not experience a loss.The method used in the selection of objects in this is purposive sampling involving 13 manufacturing companies listed on donesia Stock Exchange (IDX) for the 2017-2021 periode with an vation period of 5 (five) years with 65 samples of companies. The tical model used in this study is a multiple linear regression analysis which was carried out with the help of the SPSS version 26 for window am.The results of this study indicate that the Dividend Policy (DPR) rofitability (ROE) have a significant effect on firm value. while the debt (DER) does not show a significant effect on firm value.
Pengaruh Financial Distress terhadap Tax Avoidance (Studi Kasus Perusahaan Mining yang Terdaftar di Bursa Efek Indonesia)
Authors: Ferawati Ferawati , Bimantoro M. Rizqi Khairi
Published: June 2023

Penelitian ini bertujuan untuk menganalisis pengaruh variabel financial distress terhadap tax avoidance pada perusahaan mining yang terdaftar di Bursa Efek Indonesia (BEI). Teknik pengambilan sampel dalam penelitian ini menggunakan purposive sampling dan diperoleh sampel sebanyak 11 perusahaan dengan lima tahun periode 2016-2020. Data yang digunakan diperoleh dari Bursa Efek Indonesia (BEI). Hipotesis dalam penelitian ini diuji menggunakan aplikasi Statistical Package for The Social Sciences (SPSS). Dalam penelitian ini, variabel financial distress diukur dengan Interest Coverage Ratio (ICR) dan variabel tax avoidance diukur menggunakan model Effective Tax Rate (ETR). Hasil penelitian menunjukan bahwa financial distress tidak berpengaruh atau berpengaruh negatif terhadap tax avoidance.
ANALISIS PENGGUNAAN METODE ALTMAN Z-SCORE UNTUK PREDIKSI KEBANGKRUTAN PADA PT IMPACK PRATAMA INDUSTRI Tbk TAHUN 2018-2021
Authors: Riskiani Besta , Suartini Sri
Published: June 2023

Penelitian ini dilakukan dengan metode Altman Z-Score yang ditujukan untuk meramalkan, menganalisis, dan mengetahui suatu keadaan perusahaan sejauh mana tingkat potensi kebangkrutan pada PT Impack Pratama Industri periode 2018-2021. Penelitian dengan menggunakan dengan metode ini, dapat digunakan untuk memahami kinerja keuangan perusahaan berdasarkan hasil analisis diskriminan. Analisis diskriminan dilakukan untuk memproyeksikan kebangkrutan suatu perusahaan melalui analisis laporan keuangan perusahaan hingga lima tahun. Hasil penelitian, bahwa selama 4 tahun perusahaan berada dalam keadaan sehat dan tidak mengalami kebangkrutan bahkan nilai Z-Score terus mengalami peningkatan setiap tahun. Walaupun, sebenarnya kondisi keuangan perusahaan berfluktuatif, namun perusahaan berhasil mempertahankan kondisi kesehatannya setiap tahun.
Pengaruh Cash Position dan Market To Book Value of Equity Terhadap Dividend Payout Ratio Pada Perusahaan Manufaktur Yang Terdaftar di Bursa Efek Indonesia
Authors: Lubis Nazira Natasha , Harahap Zufrizal , Fahmi Nur Augus
Published: June 2023

Penelitian bertujuan untuk mengetahui pengaruh cash position dan market to book value of equity terhadap dividend payoutratio pada perusahaan manufaktur subsector makanan dan minuman yang terdaftar di Bursa Efek Indonesia periode 2015-2020. Data yang digunakan adalah data sekunder berupa laporan keuangan yang berasal dari website Bursa Efek Indonesia yang dianalisis dalam beberapa hipotesis. Diperoleh jumlah sampel sebanyak 6 perusahaan dari 26 populasi perusahaan. Analisis yang digunakan adalah analisis deskriptif model regresi linier berganda dengan bantuan SPSS versi 20. Hasil penelitian menunjukan bahwa secara simultan tidak terdapat pengaruh antara cash position dan market to book value of equity terhadap dividend payout ratio.