bluuebunny/crossref_metadata_2025 huggingface dataset:
Novel Genes and Genetic Loci Associated With Root Morphological Traits, Phosphorus-Acquisition Efficiency and Phosphorus-Use Efficiency in Chickpea
Authors: Thudi Mahendar , Chen Yinglong , Pang Jiayin , Kalavikatte Danamma , Bajaj Prasad , Roorkiwal Manish , Chitikineni Annapurna , Ryan Megan H. , Lambers Hans , Siddique Kadambot H. M. , Varshney Rajeev K.
Published: May 2021

Chickpea—the second most important grain legume worldwide—is cultivated mainly on marginal soils. Phosphorus (P) deficiency often restricts chickpea yields. Understanding the genetics of traits encoding P-acquisition efficiency and P-use efficiency will help develop strategies to reduce P-fertilizer application. A genome-wide association mapping approach was used to determine loci and genes associated with root architecture, root traits associated with P-acquisition efficiency and P-use efficiency, and any associated proxy traits. Using three statistical models—a generalized linear model (GLM), a mixed linear model (MLM), and a fixed and random model circulating probability unification (FarmCPU) —10, 51, and 40 marker-trait associations (MTAs), respectively were identified. A single nucleotide polymorphism (SNP) locus (Ca1_12310101) on Ca1 associated with three traits, i.e., physiological P-use efficiency, shoot dry weight, and shoot P content was identified. Genes related to shoot P concentration (NAD kinase 2, dynamin-related protein 1C), physiological P-use efficiency (fasciclin-like arabinogalactan protein), specific root length (4-coumarate–CoA ligase 1) and manganese concentration in mature leaves (ABC1 family protein) were identified. The MTAs and novel genes identified in this study can be used to improve P-use efficiency in chickpea.
The Sorghum Grain Mold Disease Complex: Pathogens, Host Responses, and the Bioactive Metabolites at Play
Authors: Ackerman Arlyn , Wenndt Anthony , Boyles Richard
Published: May 2021

Grain mold is a major concern in sorghum [Sorghum bicolor (L.) Moench] production systems, threatening grain quality, safety, and nutritional value as both human food and livestock feed. The crop’s nutritional value, environmental resilience, and economic promise poise sorghum for increased acreage, especially in light of the growing pressures of climate change on global food systems. In order to fully take advantage of this potential, sorghum improvement efforts and production systems must be proactive in managing the sorghum grain mold disease complex, which not only jeopardizes agricultural productivity and profitability, but is also the culprit of harmful mycotoxins that warrant substantial public health concern. The robust scholarly literature from the 1980s to the early 2000s yielded valuable insights and key comprehensive reviews of the grain mold disease complex. Nevertheless, there remains a substantial gap in understanding the complex multi-organismal dynamics that underpin the plant-pathogen interactions involved – a gap that must be filled in order to deliver improved germplasm that is not only capable of withstanding the pressures of climate change, but also wields robust resistance to disease and mycotoxin accumulation. The present review seeks to provide an updated perspective of the sorghum grain mold disease complex, bolstered by recent advances in the understanding of the genetic and the biochemical interactions among the fungal pathogens, their corresponding mycotoxins, and the sorghum host. Critical components of the sorghum grain mold disease complex are summarized in narrative format to consolidate a collection of important concepts: (1) the current state of sorghum grain mold in research and production systems; (2) overview of the individual pathogens that contribute to the grain mold complex; (3) the mycotoxin-producing potential of these pathogens on sorghum and other substrates; and (4) a systems biology approach to the understanding of host responses.
Feeling Deficient but Reluctant to Improve: How Perceived Control Affects Consumers' Willingness to Purchase Self-Improvement Products Under Self-Deficit Situations
Authors: Song Wei , Jin Xiaotong , Gao Jian , Zhao Taiyang
Published: May 2021

This study explored how perceived control affects consumers' willingness to purchase self-improvement products (WSP) under self-deficit situations. For this purpose, three experiments were conducted to examine the following sources of control: the controllability of self-deficits (Experiment 1); the locus of control (Experiment 2); and situational perceived control (Experiment 3). According to the results, higher perceived control can reduce consumers' defensive reaction tendencies, thus increasing their willingness to purchase products that claim to improve their current deficits. Moreover, the aforementioned effect only occurs in within-domain improvement products, rather than without-domain improvement products.
Construct Validity of the Mentalization Scale (MentS) Within a Mixed Psychiatric Sample
Authors: Richter Felix , Steinmair Dagmar , Löffler-Stastka Henriette
Published: May 2021

Introduction:The concept of mentalizing is nowadays widely used in research as well as in clinical practice. Despite its popularity, the development of an economic assessment is still challenging. The Mentalization Scale appears to be a promising measurement with good psychometric properties but lacking convergent validity with the Reflective Functioning Scale.

Objective:This study aims to test the construct validity of the Mentalization Scale through correlations with the gold standard, the Reflective Functioning Scale, within a clinical sample. Furthermore, it was of interest to replicate its internal consistency.

Methods:Twenty-six inpatients of an acute psychiatric ward in Vienna were given the Mentalization Scale (MentS). They were interviewed with the Brief Reflective Function Interview, which was coded with the Reflective Functioning Scale. Correlations and internal consistency were calculated.

Results:Concerning the primary aim of this study, the validity was satisfactory for the MentS whole-scale mentalizing as well as for the subscales self- and other-oriented mentalizing. Internal consistency was lower to the findings of the developer and close to the 0.70 threshold.

Conclusion:Our findings could foster the psychometric properties of the MentS. Furthermore, the MentS seems to be a promising measurement tool for detecting different dimensions of reflective functioning. Limitations and further research are discussed.
Effect of Hidden Vector on the Speech of PRVA
Authors: Matsui Tetsuya , Tani Iori , Sasai Kazuto , Gunji Yukio-Pegio
Published: May 2021

This study aimed to propose a novel method for designing a product recommendation virtual agent (PRVA) that can keep users motivated to interact with the agent. In prior papers, many methods of keeping users motivated postulated real-time and multi-modal interactions. The proposed novel method can be used in one-direction interaction. We defined the notion of the “hidden vector,” that is, information that is not mentioned by a PRVA and that the user can suppose spontaneously. We conducted an experiment to verify the hypothesis that PRVAs having a hidden vector are more effective than other PRVAs. As a result, it was shown that PRVAs having a hidden vector were perceived as being more persuasive than other PRVAs and strongly motivated the users to use the PRVAs. From these results, the proposed method was shown to be effective.
Translator's Style Through Lexical Bundles: A Corpus-Driven Analysis of Two English Translations of Hongloumeng
Authors: Liu Kanglong , Afzaal Muhammad
Published: May 2021

Based on a corpus-driven analysis of two translated versions ofHongloumeng(one by David Hawkes and the other by Xianyi Yang and Gladys Yang) in parallel corpora, this article investigates the use of lexical bundles in an attempt to trace the stylistic features and differences in the translations produced by the respective translators. TheHongloumengcorpus is developed at the sentence level to facilitate co-occurrence of the source texts and the two corresponding translations. For this purpose, the three-word and four-word lexical bundles were first extracted and then analyzed with respect to the functional classification proposed by Biber et al. (2004). The results of the study show that Hawkes' translation is embedded with a greater number and variety of lexical bundles than the one by the Yang couple. The study also identified the differences between the two versions which can be traced back to the deployment of different translation strategies of the translators, appearing in turn to be influenced by the language backgrounds of the translators, the translation skopos and settings, and the social, political, and ideological milieu in which the translations were produced.
Impact of Lockdown Measures on Joint Music Making: Playing Online and Physically Together
Authors: Onderdijk Kelsey E. , Acar Freya , Van Dyck Edith
Published: May 2021

A wide range of countries decided to go into lockdown to contain the coronavirus disease (COVID-19) pandemic of 2020, a setting separating people and restricting their movements. We investigated how musicians dealt with this sudden restriction in mobility. Responses of 234 people were collected. The majority of respondents (95%) resided in Belgium or the Netherlands. Results indicated a decrease of 79% of live music making in social settings during lockdown compared with before lockdown. In contrast, an increase of 264% was demonstrated for online joint music making. However, results showed that most respondents were largely or even completely unaccustomed with specialized platforms for online joint music making (e.g., JamKazam, Jamulus). Respondents reported to mostly use well-known video-conferencing platforms such as Zoom and Skype when playing together virtually. However, when such video-conferencing platforms were used, they were often not employed for synchronized playing and were generally reported to insufficiently deal with latency issues. Furthermore, respondents depending on music making as their main source of income explored online real-time methods significantly more than those relying on other income sources. Results also demonstrated an increase of 93% in the use of alternative remote joint music-making methods (e.g., recording parts separately and subsequently circulating these digital recordings). All in all, results of this study provide a more in-depth view on joint music making during the first weeks of lockdown induced by the COVID-19 pandemic of 2020, and demonstrate users’ perceptions of performance and usability of online real-time platforms as well as alternative methods for musical interaction.
Costs and Benefits of Native Language Similarity for Non-native Word Learning
Authors: Marian Viorica , Bartolotti James , van den Berg Aimee , Hayakawa Sayuri
Published: May 2021

The present study examined the costs and benefits of native language similarity for non-native vocabulary learning. Because learning a second language (L2) is difficult, many learners start with easy words that look like their native language (L1) to jumpstart their vocabulary. However, this approach may not be the most effective strategy in the long-term, compared to introducing difficult L2 vocabulary early on. We examined how L1 orthographic typicality affects pattern learning of novel vocabulary by teaching English monolinguals either Englishlike or Non-Englishlike pseudowords that contained repeated orthographic patterns. We found that overall, the first words that individuals learned during initial acquisition influenced which words they acquired later. Specifically, learning a new word in one session made it easier to acquire an orthographically similar word in the next session. Similarity among non-native words interacted with native language similarity, so that words that looked more like English were easier to learn at first, but they were less effective at influencing later word learning. This demonstrates that although native language similarity has a beneficial effect early on, it may reduce learners' ability to benefit from non-native word patterns during continued acquisition. This surprising finding demonstrates that making learning easier may not be the most effective long-term strategy. Learning difficult vocabulary teaches the learner what makes non-native words unique, and this general wordform knowledge may be more valuable than the words themselves. We conclude that native language similarity modulates new vocabulary acquisition and that difficulties during learning are not always to be avoided, as additional effort early on can pay later dividends.
Learning From Instructional Videos: Learner Gender Does Matter; Speaker Gender Does Not
Authors: Schrader Claudia , Seufert Tina , Zander Steffi
Published: May 2021

One crucial design characteristic of auditory texts embedded in instructional videos is the speaker gender, which has received some attention from empirical researcher in the recent years. Contrary to the theoretical assumption that similarity between the speaker’s and the learner’s gender might positively affect learning outcomes, the findings have often been mixed, showing null to contrary effects. Notwithstanding the effect on the outcomes, a closer look at how the speaker’s gender and speaker–learner similarities further determine cognitive variables, such as different cognitive load types, is overdue. Moreover, on the part of the learner, the role of situational interest in the learning topic that might be gender related has been neglected so far. Therefore, this study explored the role of speaker and learner gender and their interaction regarding learning outcomes. We broaden our perspective by investigating the effects of gender-related differences concerning situational interest in the topic being taught and by determining different types of cognitive load. In a 2 (female/male speaker) × 2 (female/male learner) within- and between-subject design, 95 students learned about female and male human sexual maturity with an instructional video containing auditory explanations. Analysis results indicate that speaker gender and speaker–learner gender similarity had no impact on learning gains, situational interest, and cognitive load types. However, the results demonstrate that learner’s gender, especially for the topic of female sexual maturity, matters the most in line with the assessed variables. Compared with males, females had higher learning gains, reported higher interest in the topic, and invested more germane cognitive resources. Thus, instructional designers may want to consider learner gender-dependent interest and how it can be triggered when creating videos with auditory explanations.
Impact of Scoring First on Match Outcome in the Chinese Football Super League
Authors: Liu Tianbiao , García-de-Alcaraz Antonio , Wang Hai , Hu Ping , Chen Qiu
Published: May 2021

The aim of this study was to explore the effect of scoring first on match outcomes in the Chinese Football Super League (CSL). A total of 1,116 matches in which at least one goal was scored from the 2014 to 2018 seasons were collected. Match outcomes, absolute goal differences, the minute of the first goal, match locations, and teams’ budgets were analyzed. A team’s budget was measured in terms of a team’s value at the beginning of the season, and teams were clustered into two groups (high and low budget with means of 50.77 and 13.77 million dollars, respectively). A descriptive analysis was conducted, and two generalized linear models (a multinomial logit model and a Poisson model; p < 0.05) were applied. The results showed a favorable outcome for the team that scored first both in match outcome and goal difference. Regarding the teams that scored first, 66.31% won their matches, 20.70% achieved a draw, and 12.99% lost. Specifically, home teams were more likely to win (13.42%) and less likely to lose (9.52%) or draw (3.90%) than away teams. Home teams also had a higher likelihood of obtaining a larger goal difference. Higher budget teams were more likely to win (14.90%) and less likely to lose (9.75%) or draw (5.14%) than low-budget teams. Additionally, for each minute, the team scores closer to the end of the match, and the average probability of winning increased by 0.0028. These findings can guide the strategies of coaches in different match scenarios according to the match location and the opponent’s quality.
Time Unpacking Effect on Intertemporal Decision-Making: Does the Effect Change With Choice Valence?
Authors: Yang Quan , Gong Xianmin , Xiong Jinli , Yin Shufei
Published: May 2021

People often feel that a period of time becomes longer when it is described in more detail or cut into more segments, which is known as the time unpacking effect. The current study aims to unveil how time unpacking manipulation impacts intertemporal decision making and whether the gain-loss valence of choices moderates such impacts. We recruited 87 college students (54 female) and randomly assigned them to the experimental conditions to complete a series of intertemporal choice tasks. The subjective values of the delayed choices were calculated for each participant and then analyzed. The results showed that participants perceived longer time delays and higher subjective values on the delayed gains (but not losses) in the time unpacking conditions than in the time packing conditions. These results suggest that time unpacking manipulation not only impacts time perception but also other factors, which in turn, influence the valuation of delayed outcomes and thereby intertemporal choices. The results are discussed in comparison to previous studies to highlight the complexity of the mechanism underlying the effect of time unpacking on intertemporal decision making.
Efficiency Analysis of New Rural Cooperative Medical System in China: Implications for the COVID-19 Era
Authors: Song Ke , Liu Wei-Bai , Qing Yan , Tian Meng-Nan , Pan Wen-Tsao
Published: May 2021

The sudden outbreak of coronavirus disease 2019 (COVID-19) has caused a huge impact on the Chinese residents' health and economic level. In the pandemic background, the country and its institutions have introduced pandemic-related insurance to stabilize the national situation. At this stage, insurance has played an increasingly important role in social life. With the popularization of insurance, the idea of buying insurance to avoid risk has gradually become popular among people. Among them, the New Rural Cooperative Medical System (NRCMS) has been farmers' common choice. The NRCMS, a mutual aid system created by farmers spontaneously in the country, plays a great role in guaranteeing farmers access to basic health services, alleviating poverty caused by disease and returning to poverty due to disease, and promoting poverty alleviation and rural revitalization. Given this backdrop, we study the efficiency of the NRCMS that can effectively promote poverty alleviation and rural revitalization and ensure the people's happy life. Implementing the Data Envelopment Analysis (DEA), we find that technological progress is one of the main factors influencing the efficiency of the NRCMS. Therefore, it is important to improve the technology for providing the efficiency of the NRCMS and promoting the happiness of the society.
Subcutaneous Ketamine in Depression: A Systematic Review
Authors: Cavenaghi Vitor Breseghello , da Costa Leandro Paulino , Lacerda Acioly Luiz Tavares , Hirata Edson Shiguemi , Miguel Eurípedes Constantino , Fraguas Renério
Published: May 2021

Background: Ketamine has been shown to produce a rapid and robust antidepressant effect. Though numerous routes of administration have been studied, subcutaneous (SC) has proven to be a convenient and cost-effective route making its use particularly relevant in developing countries. Here we provide a systematic review covering the use of SC racemic ketamine and esketamine in depression, including its efficacy, safety and tolerability.

Methods: A systematic literature search was carried out, from inception through March, 2021, using PubMed/MEDLINE, EMBASE and Web of Science, with no limits of language. After identifying 159 potentially relevant articles, 12 articles were selected after applying our inclusion/exclusion criteria. These comprised two randomized clinical trials, five case-reports and five retrospective studies. Given the small number of studies found and their heterogeneous nature, a meta-analysis was not considered appropriate. Here we provide a synthesis of these data including participant characteristics, dose range, efficacy, safety/ tolerability. Risk of bias was accessed using the Cochrane risk of bias tool.

Results: SC Ketamine was administered to unipolar and bipolar patients a single or multiple doses, weekly or twice-weekly, a dose-titration approach was made in major studies, dose ranged from 0.1 to 0.5 mg/Kg of racemic ketamine and 0.5–1 mg/Kg of esketamine. Across all studies, SC ketamine showed a rapid and robust antidepressant effect, with response/ remission rates from 50 to 100% following both single or multiple doses, with transitory side effects.

Conclusion: SC racemic ketamine and esketamine in depression is a promising strategy showing beneficial efficacy and tolerability. Future studies exploring the SC route, its cost-effectiveness, and a direct comparison with IV and intranasal (IN) protocols are warranted.

Systematic Review Registration: CRD42019137434
Poor Sleep and Decision-Making Disturbance Are Associated With Suicidal Ideation in Pre-natal Depression
Authors: Bao Ciqing , Xu Ling , Tang Weina , Sun Shiyu , Zhang Wenmiao , He Jincai , Zhao Ke , Xu Dongwu , Ye Xiaodan
Published: May 2021

Although many risk factors for suicidal ideation have been identified, few studies have focused on suicidal ideation and pre-natal depression. The purpose was to investigate the relationship between decision-making (DM) dysfunction and sleep disturbance on suicidal ideation in pre-natal depression. Participants included 100 women in the third trimester of pregnancy, including pregnant women with pre-natal depression who had recent suicidal ideation (n = 30), pre-natal depression without SI (n = 35) and healthy controls (n = 35). The Iowa Gambling Task (IGT) was used to evaluate the DM function and the Pittsburgh Sleep Quality Index (PSQI) was used to assess the sleep index. The Edinburgh Post-natal Depression Scale (EPDS) was used to assess suicidal ideation and the seriousness of depression. Overall, the two groups with pre-natal depression showed worse sleep quality and decreased DM function compared with healthy controls. The pre-natal depression with suicidal ideation group showed a significantly higher score in subjective sleep quality and a lower score in block 5 of IGT than the pre-natal depression without suicidal ideation group. Further correlation analysis showed that suicidal ideation positively correlated with subjective sleep quality, sleep duration, and daytime function, and negatively correlated with IGT scores. Sleep disturbance and impaired DM function may be risk factors for suicidal ideation in pre-natal depression.
Don't Make Me Angry: Frustration-Induced Anger and Its Link to Aggression in Women With Borderline Personality Disorder
Authors: Bertsch Katja , Back Sarah , Flechsenhar Aleya , Neukel Corinne , Krauch Marlene , Spieß Karen , Panizza Angelika , Herpertz Sabine C.
Published: May 2021

Aggression is a prominent interpersonal dysfunction of individuals with borderline personality disorder (BPD). In BPD aggression is predominantly reactive in nature, often triggered by frustration, provocation, or social threat and is associated with intense anger and an inability to regulate this strong, negative emotion. Building on previous research, we were interested in investigating negative emotionality in general and anger in particular in women with BPD before and after frustration induction. To achieve this, 60 medication-free women with BPD and 32 healthy women rated the intensity of negative emotions (angry, frustrated, upset, embarrassed, nervous) before and after performing a Titrated Mirror Tracing Task, which reliably induces frustration and distress. As expected, women with BPD reported significantly greater intensity of negative emotions before and after frustration than healthy women. Specifically, they showed a significantly stronger frustration-induced increase in anger, while other negative emotions remained unaffected by frustration induction. This anger increase was significantly related to aggressive behavior reported in the 2 weeks prior to the experiment, as well as to the level of frustration experienced in the experiment itself, but not with emotion dysregulation. The current data confirm the important role of frustration-induced anger independent of emotion dysregulation in BPD, in particular with regard to aggression, a prominent interpersonal dysfunction of this disorder. These findings underline the importance of interventions with particular focus on anger.
Incidence Density and Predictors of Multidrug-Resistant Tuberculosis Among Individuals With Previous Tuberculosis History: A 15-Year Retrospective Cohort Study
Authors: Cheng Qinglin , Xie Li , Wang Le , Lu Min , Li Qingchun , Wu Yifei , Huang Yinyan , Jia Qingjun , Zhao Gang
Published: May 2021

Background: To date, too little attention has been paid to monitoring and estimating the risk of incident multidrug-resistant tuberculosis (MDR-TB) among individuals with a previous tuberculosis history (PTBH). The purpose of this study was to assess the incidence of and risk factors for MDR-TB in those individuals.

Methods: Between 2005 and 2020, a large, retrospective, population-based cohort study was performed in Hangzhou, China. A multivariable Cox regression model was used to evaluate independent predictors of incident MDR-TB among individuals with PTBH.

Results: The incidence density of MDR-TB was 22.6 per 1,000 person-years (95% confidence level and an interval of 20.9–24.3) for individuals with PTBH. The incidence of MDR-TB increased significantly in individuals who

• were under 60 years old.

• were male.

• had a history of direct contact.

• came from low-income families.

• worked in high-risk occupations.

• lived in rural areas.

• had a retreatment TB history.

• had an unfavorable outcome in their previous treatment (P < 0.05).

In addition, we found that the following factors were significantly linked to the MDR-TB risk among individuals with PTBH (P < 0.05):

• sociodemographic factors such as the 21–30 and 31–40 year age groups, or a history of direct contact.

• clinical factors like passive modes of TB case finding (PMTCF), human immunodeficiency virus infection, unfavorable treatment outcomes, retreated TB history, non-standardized treatment regimens of retreatment TB patients, and duration of pulmonary cavities (DPC).

• microbiological factors, such as duration of positive sputum culture.

We also found that the 21–30 year age group, low family income, and PMTCF were significantly linked to incident MDR-TB only in males with PTBH, whilst the 41–50 year age group, extended treatment course, and DPC were significantly associated with female MDR-TB only.

Conclusion: The incidence of MDR-TB was high, with a higher rate among subjects with a history of direct contact and unfavorable treatment outcomes. There was a gender difference in the incidence density and risk factors of MDR-TB among individuals with PTBH. Long-term monitoring and gender-specific risk-factor modifications should be given to individuals with PTBH.
The Evolution of Technology and Physical Inactivity: The Good, the Bad, and the Way Forward
Authors: Woessner Mary N. , Tacey Alexander , Levinger-Limor Ariella , Parker Alexandra G. , Levinger Pazit , Levinger Itamar
Published: May 2021

Since the beginning of time people explored and developed new technologies to make their activities of daily living less labour intense, more efficient and, consequently, more sedentary. In addition, technological advances in medicine throughout history have led to a substantial increase in life expectancy. However, the combination of increased sedentary behaviour and increased life-expectancy resulted in a sharp increase in overweight and obesity related chronic conditions and illness. Although people may live longer, they are doing so with poorer physical function and a reduced quality of life. In this review we explore how technological advances have influenced people's sedentary behaviour and, through the lens of the affective-reflective theory (ART), we propose a means by which technology could be repurposed to encourage greater engagement in physical activity.
Promotion of Pre-natal Education Courses Is Associated With Reducing the Rates of Caesarean Section: A Case-Control Study
Authors: Tang Yunhui , Gao Jing , Sun Liping , Gao Yifei , Guo Fang , Chen Qi
Published: May 2021

Objective: The number of women having a caesarean section has significantly increased worldwide, in particular in China. Maternal requestion makes a moderate contribution to this increased rate in China. Reducing the caesarean section rate is now becoming a big challenge to midwives and obstetricians as well as health policymakers in China. Our recent survey found that pre-natal education course had some positive effects on the reduction of caesarean section on maternal request. However, pre-natal education course is relatively new in China. In this study, we investigated whether pre-natal education course influences delivery mode in the largest tertiary women's hospital in China.

Methods: In this retrospective study, during the study period, 644 pregnant women attended a pre-natal education course and 4,134 pregnant women did not. Data on maternal age, parity, gravida, delivery mode, delivery weeks, birthweight, gestational age at attending pre-natal education course and maternal body mass index before pregnancy were collected and analysed.

Results: The numbers of women who attempted vaginal delivery were significantly higher in women who attended a pre-natal education course, compared to women who did not (87 vs. 60%). In addition, the rate of caesarean section on maternal request was 23% in women who attended a pre-natal education course.

Conclusion: Attendance of a pre-natal education course influences the mode of delivery and reduces the unnecessary caesarean section in China. Our findings suggest that the promotion of pre-natal education courses is important to reduce the higher caesarean section rate in China, by midwives or obstetricians or health policy-makers as part of China's strategy.
Health Related Social Needs Among Chinese American Primary Care Patients During the COVID-19 Pandemic: Implications for Cancer Screening and Primary Care
Authors: Tsui Jennifer , Yang Annie , Anuforo Bianca , Chou Jolene , Brogden Ruth , Xu Binghong , Cantor Joel C. , Wang Su
Published: May 2021

Research Objective: Initiatives to address social determinants of health (SDOH) and measure health-related social needs (HRSN) within clinic settings are increasing. However, few have focused on the specific needs of Asian Americans (AA). We examine the prevalence of HRSN during a period spanning the COVID-19 pandemic to inform strategies to improve cancer screening and primary care among AA patients.

Methods: We implemented a self-administered HRSN screening tool in English and Chinese, traditional (T) or simplified (S) text, within a hospital-affiliated, outpatient primary care practice predominantly serving AA in New Jersey. HRSN items included food insecurity, transportation barriers, utility needs, interpersonal violence, housing instability, immigration history, and neighborhood perceptions on cohesion and trust. We conducted medical chart reviews for a subset of participants to explore the relationship between HRSN and history of cancer screening.

Results: Among 236 participants, most were Asian (74%), non-US born (79%), and privately insured (57%). One-third responded in Chinese (37%). Half reported having ≥1 HRSN. Interpersonal violence was high across all participants. Transportation needs were highest among Chinese-T participants, while food insecurity and housing instability were higher among Chinese-S participants. Lower-income patients had higher odds of having ≥2 HRSN (OR:2.53, 95% CI: 1.12, 5.98). Older age and public insurance/uninsured were significantly associated with low neighborhood perceptions.

Conclusions: We observed higher than anticipated reports of HRSN among primary care patients in a suburban, hospital-affiliated practice serving AA. Low neighborhood perceptions, particularly among Chinese-S participants, highlight the importance of addressing broader SDOH among insured, suburban AA patients. These study findings inform the need to augment HRSN identification to adequately address social needs that impact health outcomes and life course experiences for Asian patients. As HRSN measuring efforts continue, and COVID-19's impact on the health of minority communities emerge, it will be critical to develop community-specific referral pathways to connect AA to resources for HRSN and continue to address more upstream social determinants of health for those who are disproportionately impacted.
Ameliorative Effects of Component Chinese Medicine From Curcumae Rhizoma and Sparganii Rhizoma, a Traditional Herb Pair, on Uterine Leiomyoma in a Rat Model
Authors: Zhang Li , Xu Qiuxia , Li Yao , Zhao Hui , Shi Xingming , Peng Fu , Yu Chenghao
Published: May 2021

Uterine leiomyoma (UL), common benign tumors in women of child-bearing age, are believed to be caused mainly by Qi stagnation and blood stasis, according to a theory of traditional Chinese medicine. Curcumae Rhizoma and Sparganii Rhizoma (CRSR) is a classical herb pair that activates blood circulation to dissipate blood stasis. The purpose of this study was to explore the prevention and treatment effects of CRSR component compatibility on UL in rats. We randomly assigned adult female non-pregnant rats into three groups: a normal control (NC) group, a UL model group, and a CRSR treatment group. We administered to the UL and CRSR groups oral gavage diethylstilbestrol and injected them with progesterone (P) to establish UL for 5 weeks. The CRSR group received a CRSR medicinal solution after daily modeling. The uterus morphology of the UL group showed significantly more swelling than did that of the NC group, and we found no significant abnormalities in the morphology of the CRSR group. The pathological changes associated with UL were relieved in the CRSR group. CRSR improved the related parameters of the uterus and ovarian coefficients, significantly reducing the concentrations of P in the serum and the concentrations of estradiol, P, estrogen receptor, and P receptor in the uterus and ovary. In addition, CRSR significantly improved the abnormal blood conditions of UL, shown by decreases in plasma viscosity, the erythrocyte sedimentation rate equation K value, and erythrocyte aggregation index. Therefore, CRSR component compatibility may prevent and cure UL through the above ways.
Machine Learning-Based Modeling of Spatio-Temporally Varying Responses of Rainfed Corn Yield to Climate, Soil, and Management in the U.S. Corn Belt
Authors: Xu Tianfang , Guan Kaiyu , Peng Bin , Wei Shiqi , Zhao Lei
Published: May 2021

Better understanding the variabilities in crop yield and production is critical to assessing the vulnerability and resilience of food production systems. Both environmental (climatic and edaphic) conditions and management factors affect the variabilities of crop yield. In this study, we conducted a comprehensive data-driven analysis in the U.S. Corn Belt to understand and model how rainfed corn yield is affected by climate variability and extremes, soil properties (soil available water capacity, soil organic matter), and management practices (planting date and fertilizer applications). Exploratory data analyses revealed that corn yield responds non-linearly to temperature, while the negative vapor pressure deficit (VPD) effect on corn yield is monotonic and more prominent. Higher mean yield and inter-annual yield variability are found associated with high soil available water capacity, while lower inter-annual yield variability is associated with high soil organic matter (SOM). We also identified region-dependent relationships between planting date and yield and a strong correlation between planting date and the April weather condition (temperature and rainfall). Next, we built machine learning models using the random forest and LASSO algorithms, respectively, to predict corn yield with all climatic, soil properties, and management factors. The random forest model achieved a high prediction accuracy for annual yield at county level as early as in July (R2 = 0.781) and outperformed LASSO. The gained insights from this study lead to improved understanding of how corn yield responds to climate variability and projected change in the U.S. Corn Belt and globally.
SYMBALS: A Systematic Review Methodology Blending Active Learning and Snowballing
Authors: van Haastrecht Max , Sarhan Injy , Yigit Ozkan Bilge , Brinkhuis Matthieu , Spruit Marco
Published: May 2021

Research output has grown significantly in recent years, often making it difficult to see the forest for the trees. Systematic reviews are the natural scientific tool to provide clarity in these situations. However, they are protracted processes that require expertise to execute. These are problematic characteristics in a constantly changing environment. To solve these challenges, we introduce an innovative systematic review methodology: SYMBALS. SYMBALS blends the traditional method of backward snowballing with the machine learning method of active learning. We applied our methodology in a case study, demonstrating its ability to swiftly yield broad research coverage. We proved the validity of our method using a replication study, where SYMBALS was shown to accelerate title and abstract screening by a factor of 6. Additionally, four benchmarking experiments demonstrated the ability of our methodology to outperform the state-of-the-art systematic review methodology FAST2.
Symptom-Based Identification of G-4 Chili Leaf Diseases Based on Rotation Invariant
Authors: Das Chagas Silva Araujo Sufola , Malemath V. S. , Sundaram K. Meenakshi
Published: May 2021

Instinctive detection of infections by carefully inspecting the signs on the plant leaves is an easier and economic way to diagnose different plant leaf diseases. This defines a way in which symptoms of diseased plants are detected utilizing the concept of feature learning (Sulistyo et al., 2020). The physical method of detecting and analyzing diseases takes a lot of time and has chances of making many errors (Sulistyo et al., 2020). So a method has been developed to identify the symptoms by just acquiring the chili plant leaf image. The methodology used involves image database, extracting the region of interest, training and testing images, symptoms/features extraction of the plant image using moments, building of the symptom vector feature dataset, and finding the correlation and similarity between different symptoms of the plant (Sulistyo et al., 2020). This will detect different diseases of the plant.
From Warranty Voids to Uprising Advocacy: Human Action and the Perceived Moral Patiency of Social Robots
Authors: Banks Jaime
Published: May 2021

Moral status can be understood along two dimensions: moral agency [capacities to be and do good (or bad)] and moral patiency (extents to which entities are objects of moral concern), where the latter especially has implications for how humans accept or reject machine agents into human social spheres. As there is currently limited understanding of how people innately understand and imagine the moral patiency of social robots, this study inductively explores key themes in how robots may be subject to humans’ (im)moral action across 12 valenced foundations in the moral matrix: care/harm, fairness/unfairness, loyalty/betrayal, authority/subversion, purity/degradation, liberty/oppression. Findings indicate that people can imagine clear dynamics by which anthropomorphic, zoomorphic, and mechanomorphic robots may benefit and suffer at the hands of humans (e.g., affirmations of personhood, compromising bodily integrity, veneration as gods, corruption by physical or information interventions). Patterns across the matrix are interpreted to suggest that moral patiency may be a function of whether people diminish or uphold the ontological boundary between humans and machines, though even moral upholdings bare notes of utilitarianism.
Surface Flow Velocities From Space: Particle Image Velocimetry of Satellite Video of a Large, Sediment-Laden River
Authors: Legleiter Carl J. , Kinzel Paul J.
Published: May 2021

Conventional, field-based streamflow monitoring in remote, inaccessible locations such as Alaska poses logistical challenges. Safety concerns, financial considerations, and a desire to expand water-observing networks make remote sensing an appealing alternative means of collecting hydrologic data. In an ongoing effort to develop non-contact methods for measuring river discharge, we evaluated the potential to estimate surface flow velocities from satellite video of a large, sediment-laden river in Alaska via particle image velocimetry (PIV). In this setting, naturally occurring sediment boil vortices produced distinct water surface features that could be tracked from frame to frame as they were advected by the flow, obviating the need to introduce artificial tracer particles. In this study, we refined an end-to-end workflow that involved stabilization and geo-referencing, image preprocessing, PIV analysis with an ensemble correlation algorithm, and post-processing of PIV output to filter outliers and scale and geo-reference velocity vectors. Applying these procedures to image sequences extracted from satellite video allowed us to produce high resolution surface velocity fields; field measurements of depth-averaged flow velocity were used to assess accuracy. Our results confirmed the importance of preprocessing images to enhance contrast and indicated that lower frame rates (e.g., 0.25 Hz) lead to more reliable velocity estimates because longer capture intervals allow more time for water surface features to translate several pixels between frames, given the relatively coarse spatial resolution of the satellite data. Although agreement between PIV-derived velocity estimates and field measurements was weak (R2 = 0.39) on a point-by-point basis, correspondence improved when the PIV output was aggregated to the cross-sectional scale. For example, the correspondence between cross-sectional maximum velocities inferred via remote sensing and measured in the field was much stronger (R2 = 0.76), suggesting that satellite video could play a role in measuring river discharge. Examining correlation matrices produced as an intermediate output of the PIV algorithm yielded insight on the interactions between image frame rate and sensor spatial resolution, which must be considered in tandem. Although further research and technological development are needed, measuring surface flow velocities from satellite video could become a viable tool for streamflow monitoring in certain fluvial environments.
Engineering Plants to Improve Their Immune System
Authors: Leibman-Markus Meirav , Bar Maya
Published: May 2021

Much like humans, plants suffer from all kinds of diseases. In our lab, we study the immune system of plants. Using a technology called CRISPR, which enables us to edit the DNA of different creatures, we made changes in the plant immune system, with the goal of strengthening it. We succeeded in strengthening the plant immune system, and produced plants that are more resistant to diseases. Producing plants with a more active immune system could help us deal with plant diseases and improve agricultural crops.
Interrelations Between Astrochemistry and Galactic Dynamics
Authors: Mendoza Edgar , Duronea Nicolas , Ronsó Daniele , Corazza Lia C. , van der Tak Floris , Paron Sergio , Nyman Lars-Åke
Published: May 2021

This paper presents a review of ideas that interconnect astrochemistry and galactic dynamics. Since these two areas are vast and not recent, each one has already been covered separately by several reviews. After a general historical introduction, and a needed quick review of processes such as stellar nucleosynthesis that gives the base to understand the interstellar formation of simple chemical compounds (e.g., H2, CO, NH3, and H2O), we focus on a number of topics that are at the crossing of the two big areas, dynamics and astrochemistry. Astrochemistry is a flourishing field that intends to study the presence and formation of molecules as well as the influence of them on the structure, evolution, and dynamics of astronomical objects. The progress in the knowledge on the existence of new complex molecules and of their process of formation originates from the observational, experimental, and theoretical areas that compose the field. The interfacing areas include star formation, protoplanetary disks, the role of the spiral arms, and the chemical abundance gradients in the galactic disk. It often happens that the physical conditions in some regions of the interstellar medium are only revealed by means of molecular observations. To organize a rough classification of chemical evolution processes, we discuss about how astrochemistry can act in three different contexts, namely, the chemistry of the early universe, including external galaxies, star-forming regions, and asymptotic giant branch (AGB) stars and circumstellar envelopes. We mention that our research is stimulated by plans for instruments and projects, such as the ongoing Large Latin American Millimeter Array (LLAMA), which consists in the construction of a 12 m sub-mm radio telescope in the Andes. Thus, modern and new facilities can play a key role in new discoveries not only in astrochemistry but also in radio astronomy and related areas. Furthermore, the research on the origin of life is also a stimulating perspective.
Colliding-Wind Binaries as a Source of TeV Cosmic Rays
Authors: Kowal Grzegorz , Falceta-Gonçalves Diego A.
Published: May 2021

In addition to gamma-ray binaries which contain a compact object, high-energy and very high–energy gamma rays have also been detected from colliding-wind binaries. The collision of the winds produces two strong shock fronts, one for each wind, both surrounding a shock region of compressed and heated plasma, where particles are accelerated to very high energies. Magnetic field is also amplified in the shocked region on which the acceleration of particles greatly depends. In this work, we performed full three-dimensional magnetohydrodynamic simulations of colliding winds coupled to a code that evolves the kinematics of passive charged test particles subject to the plasma fluctuations. After the run of a large ensemble of test particles with initial thermal distributions, we show that such shocks produce a nonthermal population (nearly 1% of total particles) of few tens of GeVs up to few TeVs, depending on the initial magnetization level of the stellar winds. We were able to determine the loci of fastest acceleration, in the range of MeV/s to GeV/s, to be related to the turbulent plasma with amplified magnetic field of the shock. These results show that colliding-wind binaries are indeed able to produce a significant population of high-energy particles, in relatively short timescales, compared to the dynamical and diffusion timescales.