bluuebunny/crossref_metadata_2025 huggingface dataset:
A case report of recalcitrant non union humerus treated with on lay fibular bone grafting and locking compression plate
Authors: Bheemisetty Vivekananda , Vamshi Rentala , Sreenivasa Reddy S. , Thimma Reddy Y.
Published: February 2018

Nonunion of diaphyseal fractures of the humerus are frequently seen in clinical practice (incidence of up to 15% in certain studies) and osteosynthesis using dynamic compression plates, intra medullary nails and Ilizarov fixators have been reported previously. Locking compression plates (LCP) are useful in the presence of disuse osteoporosis, segmental bone loss and cortical defects that preclude strong fixation. Fixation using a compression plate and a non-vascularised fibular graft achieves good outcome for infected non-union of the humerus despite prior multiple failed surgeries. We report a failed case of fracture shaft humerus which was operated three times, first with DCP and next two times with DCP and autologous cancellous bone graft from iliac crest. The patient is now treated with LCP and on lay fibular bone grafting.
Stress in Parents of Children and Adolescents with Down Syndrome
Authors: Oliveira Lorrane Caroline de , Eduardo Iriana Moraes , Prudente Cejane Oliveira Martins , Ribeiro Maysa Ferreira Martins
Published: February 2018

The aim of this study is analysing the presence of worried levels of general and parental stress in parents who has children and teenagers with down´s syndrome. This is a transversal and analytic study that happened in five instituctions that assist people with deficiency in Goiania, Góias. The sample consists of forty parents. Instruments of analyses of the stress: List of symptoms of stress to adults of LIPP (ISSL). The analyses of the general stress happened through of LIPP test: most of the parents wasn´t stressed but those who had stress were in the phase of resistance. In respect of the manifestation of the parental stress: the average level of stress of the parents was low in the three subscales and in the entire questionaire, however, 35% of the parents showed worried levels of stress. Parents of teenagers showed average level higher than the parents of children in the subscale dysfunctional interaction genitor-child. There was bigger proportion of parents of teenagers they have worried levels of stress. Comparison between the socioeconomic data and the parental stress revealed that the stress is bigger in parents who have studied a little bit. The results show that it´s necessary to help the emotional health of parents and children with down´s syndrome with the focus to the parents of teenagers.

Estresse em Pais de Crianças e Adolescentes com Síndrome de Down

Estudo com objetivo de avaliar a presença de níveis de estresse geral e parental em pais de crianças e adolescentes com síndrome de Down. Trata-se de um estudo transversal e analítico, realizado em cinco instituições que atendem pessoas com deficiência em Goiânia, Goiás. Amostra foi composta por 40 pais. Instrumentos de avaliação do estresse: Inventário de Sintomas de Estresse para Adultos de Lipp (ISSL), Parenting Stress Index Short Form (PSI/SF). Quanto à avaliação do estresse geral por meio do ISSL: a maioria dos pais não estavam estressados. Quanto à manifestação do estresse parental: o escore médio do estresse dos pais foi baixo nas três subescalas e no questionário total, entretanto, 35% dos pais apresentaram níveis de estresse considerado preocupante. Pais de adolescentes apresentaram escore médio mais alto do que pais de crianças, na subescala interação disfuncional genitor-criança (p=0,03). Houve maior proporção de pais de adolescentes com nível de estresse considerado preocupante (n= 54,50%, p=0,008). A comparação entre os dados socioeconômicos e o estresse parental revelou que o estresse é maior em pais com menos escolaridade. Os resultados chamam atenção para a necessidade de assistir a saúde emocional de pais de filhos com síndrome de Down, com foco para os pais de adolescentes.
The Influence of Classroom Management toward Students’ English Achievement at SMU Muhammadiyah Salatiga (A Case Study of Second Year Students of SMU Muhammadiyah Salatiga in the Academic Year of 2004/2005)
Authors: Triyono Triyono
Published: February 2018

This research aims to find out the influence of classroom management toward students’ achievement in English.  The research was conducted at SMU Muhammadiyah Salatiga, Central Java, Indonesia. The writer focuses on the second year students in the academic year of 2004/2005. It is a Quantitative Research. Questionnaire and direct observation are the instruments used to take the data. The score of classroom management of SMU Muhammadiyah Salatiga is 87.6%, fairly high. While the score level of the second year students of SMU Muhammadiyah Salatiga is 72%. This score level is satisfactory category of achievement level of most students. It means that better classroom management influences better English achievement.Keywords:Classroom Management; Achievement;  SMU Muhammadiyah
The Types of Cohesion Used in the ‘Issues of the Day’ Strip in the Jakarta Post
Authors: Agustina Wulan
Published: February 2018

This study is aimed at describing discourse studies especially at cohesion from reader’s opinion strip. This is literary research, so the writer uses descriptive qualitative approach. In this research, documentation and note taking technique are used to collect the data. There are two objectives of the research: 1) to carry out the types of grammatical cohesion used in the “Issues of the Day” strip in The Jakarta Post on March 2012 edition and 2) to find out the types of lexical cohesion used in the “Issues of The Day” strip in The Jakarta Post on March 2012 edition. After investigating the English sentences used in the “Issues of the Day” strip in The Jakarta Post on March 2012 edition, the writer found several findings as follows: 1) based on the analysis of grammatical cohesion, the writer found there are references, substitutions, ellipsis, and conjunctions; 2) based on the analysis of lexical cohesion, the writer found repetitions, synonyms, hyponyms, meronyms, antonyms, and collocations. The writer expects that it is able to contribute the science of linguistic and able to be guidance for all readers.Keywords:cohesion;   ‘Issues of the Day’ strip
A Contrastive Analysis of Interrogative Sentences in English and Indonesian
Authors: Umami Mashlihatul
Published: February 2018

The aim of this paper is to investigate the forms of questions in English and Indonesian in order to identify the similarities and differences between them. CA may look at linguistic structures in a twofold way: predictability power and wash back effect (Cheng, Watanabe & Curtis, 2004). The former deals with foreseeing the areas of problems the English learners may commit and the latter refers to the effect of diagnostic value of CA on improvement of teaching processes. In this case, the researcher emphasizes her study in analyzing CA based on the first perspective; this study focuses on interrogative sentences which are in the form of questions which play an important role in learning English among junior English students. This study has found the differences and similarities between Indonesian and English. Recognizing this will contribute to the accuracy of English questions made by the students.Keywords: Interrogative sentences; English; Indonesian; Contrastive analysis, accuracy
A Taxonomy of Asynchronous Instructional Video Styles
Authors: Chorianopoulos Konstantinos
Published: February 2018

Many educational organizations are employing instructional videos in their pedagogy, but there is a limited understanding of the possible video formats. In practice, the presentation format of instructional videos ranges from direct recording of classroom teaching with a stationary camera, or screencasts with voice-over, to highly elaborate video post-production. Previous work evaluated the effectiveness of several production styles, but there has not been any consistent taxonomy, which would have made comparisons and meta-analyses possible. Therefore, we need a taxonomy of instructional video formats that facilitates the understanding of the landscape of available instructional video production styles. For this purpose, we surveyed the research literature and examined contemporary video-based courses, which have been produced by diverse educational organizations and teachers across several academic disciplines. We organized instructional video styles in two dimensions according to the level of human presence and to the type of instructional media. In addition to organizing existing instructional videos in a comprehensive way, the proposed taxonomy offers a design space, which should facilitate choice, as well as the preparation of novel video formats.
A Sharing Mind Map-oriented Approach to Enhance Collaborative Mobile Learning With Digital Archiving Systems
Authors: Chang Jui-Hung , Chiu Po-Sheng , Huang Yueh-Min
Published: February 2018

With the advances in mobile network technology, the use of portable devices and mobile networks for learning is not limited by time and space. Such use, in combination with appropriate learning strategies, can achieve a better effect. Despite the effectiveness of mobile learning, students’ learning direction, progress, and achievement may differ. Thus, the enhancement of learners’ opinions on the usability and interactivity during mobile learning are challenging issues to overcome. This study developed a sharing mind map-oriented mobile learning system integrated with valuable information preserved in a digital archiving system. In addition to the functions of traditional mind maps, this system also enabled students to complete and record relevant information that they had found onto the mind map and further improve the integrity of their own knowledge. To investigate the effectiveness of this teaching approach, this study added digital archive data and used mind map sharing to help learners develop knowledge.  By using the proposed approach, students were able to perform self-assessment on learning content, choose appropriate learning directions, and progress according to their level of learning. At the same time, they could collaboratively learn with peers to engage themselves more deeply in their learning. That is, their learning motivation could be constantly triggered through the observations and sharing of mind maps from one to another. This study selected sixth graders as its research subjects in two classes at the school where one researcher works. There were 31 and 30 valid samples in the experimental group and control group, respectively, with a total of 61 students. The experimental group was conducted by using sharing mind map with corresponding geographical archived information to investigate the effectiveness of sharing mind map (SMM) in mobile learning; on the other hand, the control group was conducted by using a traditional learning approach. The outcomes indicate that students’ learning performance could be enhanced by using archived information SMM mobile learning.
Content is King: An Analysis of How the Twitter Discourse Surrounding Open Education Unfolded From 2009 to 2016
Authors: Paskevicius Michael , Veletsianos George , Kimmons Royce
Published: February 2018

Inspired by open educational resources, open pedagogy, and open source software, the openness movement in education has different meanings for different people. In this study, we use Twitter data to examine the discourses surrounding openness as well as the people who participate in discourse around openness. By targeting hashtags related to open education, we gathered the most extensive dataset of historical open education tweets to date (n = 178,304 tweets and 23,061 users) and conducted a mixed methods analysis of openness from 2009 to 2016. Findings show that the diversity of participants has varied somewhat over time and that the discourse has predominantly revolved around open resources, although there are signs that an increase in interest around pedagogy, teaching, and learning is emerging.
Decision, Implementation, and Confirmation: Experiences of Instructors behind Tourism and Hospitality MOOCs
Authors: Lin Jingjing , Cantoni Lorenzo
Published: February 2018

As the popularity of Massive Open Online Courses (MOOCs) continues to grow, studies are emerging to investigate various topics in this area. Most have focused on the learners’ perspective, leaving a gap in the literature about MOOC instructors. The current research—conducted in the field of tourism and hospitality—explored early experiences of MOOC instructors as they progressed through three stages of the innovation-decision process: decision, implementation, and confirmation. The tourism and hospitality field was chosen because its related industries contribute significantly to global employment, and training is one of their critical success factors. MOOCs possess a good potential to benefit tourism and hospitality education, yet tourism and hospitality MOOCs are under-researched. Semi-structured interviews were conducted with six instructors who offered tourism and hospitality MOOCs between 2008 and 2015. Findings revealed that: (1) the instructors’ decisions to offer MOOCs were mostly influenced by their institutes’ interests in MOOCs; (2) when the instructors implemented MOOCs, a pattern of action emerged, which included six phases and one cross-phase element—prepare, design, develop, launch, deliver, and evaluate—and across phases—support and train; (3) most instructors chose to avoid risk in their adoption and implementation of the MOOCs, staying away from innovative teaching or learning activities such as peer-review assessments and collaborative activities; and (4) half of the instructors intended to repeat the experience of teaching in the MOOCs format in the future.
Family Business’s Transitioning to Circular Economy Model: The Case of “Mercadona”
Authors: Nuñez-Cacho Pedro , Molina-Moreno Valentín , Corpas-Iglesias Francisco A. , Cortés-García Francisco J.
Published: February 2018

Sustainability addresses environmental and social issues affecting this and future generations. When family businesses perceive that the community is disrupted, recognize an environmental problem and respond by implementing new environmental policies or regulations, the family business’s socio-emotional values press to transition to a more sustainable production system, such as the ‘Circular Economy.’ Drawing on the Dubin (1978) methodology—a paradigm for building models through deduction—we design a sustainable model, which shows family businesses’ responses to changes in the environment. It explains the reasons why family firms transition to the Circular Economy, based on the theory of Socio-Emotional Wealth (SEW). We check the model through the case study of the food retail leader in the Spanish market—Mercadona—which applies policies about energy, resources and waste to become a Circular Economy business model. Because of the strong family character of Mercadona, this case can be useful for the decision-making of other family businesses.
PENGEMBANGAN E-BOOK BERBASIS PROBLEM BASED LEARNING-GIS UNTUK MENINGKATKAN KECAKAPAN BERFIKIR KERUANGAN PADA SISWA KELAS X SMA N 1
Authors: Yusup Yasin , Santoso Sigit , Istifarida Binti
Published: February 2018

Tujuan dari penelitian ini adalah: (1) Mengidentifikasi kebutuhan bel­ajar siswa kelas X SMAN 1 Sragen 2016/2017, (2) menentukan kelayakan Pem­belajaran Soal Berbasis GIS (PBL-GIS) e-book yang dikembangkan di SMA N 1 Sragen tahun 2016/2017, (3) menentukan perbedaan kemampuan berpikir spasial sebelum dan sesudah menggunakan e-book PBL-GIS pada materi pelajaran Lithosfer di kelas X IPS SMA N 1 Sragen 2016/2017. Penelitian ini merupakan penelitian dan pengembangan (R & D). Tahapan R & D yang digunakan dalam penelitian ini adalah model ADDIE (Analysis, Design, Development, Implementa­tion, Evaluation). Hasil penelitian menunjuk­kan: (1) kebutuhan siswa dalam proses pembelajaran antar media lain yang dikemas dengan kreatif dan tidak monoton dalam teks, namun perlu ditambahkan video, begitu pula penggunaan model pembelajaran outdoor bagi siswa untuk segera kenali kejadian yang terjadi di sekitarnya; (2) hasil validasi tim ahli menunjukkan nilai rata-rata 73,2% termasuk dalam kriteria yang memenuhi syarat. Uji coba tanggapan siswa menunjukkan respon positif dengan persentase 83,2% termasuk kriteria yang san­gat layak; (3) perhitungan efektivitas media pembelajaran menggunakan t-test dan hasil tarithmetic = 10,244> ttabel = 1,67. Ini berarti hipotesis penelitian diterima atau dengan kata lain, ada perbedaan yang signifikan antara kemampuan berpikir spasial siswa sebe­lum dan sesudah menggunakan buku berbasis PBL-GIS dalam materi pelajaran litosfer di kelas X IPS SMAN 1 Sragen. di tahun 2016/2017.

 

Kata kunci: metode penelitian dan pengembangan, e-Book Problem Based Learning-GIS, Keterampilan Berpikir Spasial, Litosfer.

 
CHEMICAL COMPOSITIONS AND BIOLOGICAL PROPERTIES OF ESSENTIAL OILS FROM ZANTHOXYLUM RHETSA (ROXB.) DC AND ZANTHOXYLUM LIMONELLA ALSTON
Authors: Wongkattiya Nalin , Akekawatchai Chareeporn , Sanguansermsri Phanchana , Fraser Ian Hamilton , Pratoomsoot Chayanin , Sanguansermsr Donruedee
Published: February 2018

Background: Zanthoxylum rhetsa (Roxb.) DC and Zanthoxylum limonella Alston are spices for flavouring in indigenous Thai food. They are traditionally used as an aromatic, astringent, antimicrobial, antiseptic and antidiabetic agent. The purpose of this study is to examine their chemical compositions and evaluate antibacterial, antioxidant and anticancer properties of the essential oils.

Materials and Methods: The essential oils of Z. rhetsa and Z. limonella were analysed for phytochemical constituents by Gas chromatography–mass spectrometry (GC-MS). The antibacterial activity was determined against several bacteria using the microdilution method. Antioxidant capacity was determined by free radical scavenger 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2-azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) methods. The anticancer activity was determined with two breast cancer cell lines (MCF-7 and MDA-MB-231) and the normal African green monkey kidney epithelial (Vero) cell line and using MTT assay.

Results: Sabinene (22.51%) and terpinene-4-ol (32.33%) were found to be major components of Z. rhetsa essential oil while limonene (57.94%) and alpha-phelladrene (15.54%) were the major components of Z. limonella essential oil. Essential oil from Z. limonella exhibited broad spectrum antibacterial activity. Z. rhetsa and Z. limonella essential oils exhibited moderate antioxidant activity. The essential oil from Z. rhetsa possessed the ability to inhibit breast cancer cell (MCF-7 and MDA-MB-231) proliferation and cell viability.

Conclusion: This study suggest that the essential oils from Z. limonella and Z. rhetsa could be applied as safe antibacterial and antioxidant agents for food and have the potential for further development of new anticancer agents.
IN VITRO ANTI-INFLAMMATORY ACTIVITY OF THE COMPONENTS OF AMOMUM TSAO-KO IN MURINE MACROPHAGE RAW 264.7 CELLS
Authors: Choi Chun Whan , Shin Ju Young , Seo Changon , Hong Seong Su , Ahn Eun-Kyung , Jung Young Hoon , Oh Joa Sub
Published: February 2018

Background: Plants still remain the prime source of drugs for the treatment of inflammation and can provide leads for the development of novel anti-inflammatory agents.

Material and methods: An in vitro bioassay guide revealed that the 80% ethanol (EtOH) extract of the whole plant, Amomum tsao-ko (Zingiberaceae), displayed anti-inflammatory activity after assessing its effects on murine macrophage RAW 264.7 cells.

Result: Phytochemical study of the 80% EtOH extract of Amomum tsao-ko led to the isolation of eight compounds: 4-hydroxy-3-methoxy-benzoic acid (1), meso-hannokinol (2), (+)-hannokinol (3), coumaric acid (4), 4-hydroxy-benzoic acid (5), (+)-epicatechin (6), (-)-catechin (7), and myrciaphenone A (8). The results indicated that two of the isolated components, (+)-epicatechin (6) and (-)-catechin (7), inhibited the production of nitric oxide (NO) significantly in lipopolysaccharide treated RAW 264.7 cells.

Conclusion: LPS-induced interleukin tumor necrosis factor-alpha (TNF-), IL-1β and IL-10 production was also decreased in a dose-dependent manner. In addition, western blot analysis revealed that (+)-epicatechin (6) and (-)-catechin (7) reduced the expression of inducible nitric oxide synthase and inhibited nuclear localization of nuclear factor kappa-B (NF-κB).
HEPATOPROTECTIVE ACTIVITY OF COSTUS SPECIOSUS (KOEN. EX. RETZ.) AGAINST PARACETAMOL-INDUCED LIVER INJURY IN MICE
Authors: AlSaadi Baiaan H. , AlHarbi Shoaa H. , Ibrahim Sabrin R. M. , El-Kholy Amal A. , El-Agamy Dina S. , Mohamed Gamal A.
Published: February 2018

Background: Liver diseases are a common cause of mortality and morbidity over the world. It is caused mainly by toxic chemicals and chemotherapeutic agents. Costus speciosus (Koen ex. Retz.) (Zingiberaceae) is widely employed in various traditional medicines for the prevention and treatment of different aliments. The purpose of this study is to assess the protective effect of C. speciosus rhizomes MeOH extract against the injury of the liver induced by paracetamol (PA) in mice.

Material and Methods: The mice were pretreated for seven days with distilled H2O, silymarin 12 mg/kg or 100 and 200 mg/kg MeOH extract. Then, PA (750 mg/kg) was also intra-peritoneal administrated once a day. Animals were euthanatized 24 h after the damage inducement. The levels of the serum enzymes aspartate aminotransferase (AST), alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate aminotransferase, in addition to the tumor necrosis factor-alpha (TNF-α), were determined. Moreover, the histopathological examination was carried out.

Results: Administration of the MeOH extract (200 mg/kg) showed improvement in the toxic effects of PA through significant fall on the serum markers enzymes of liver damage: AST, ALT, and ALP, as well as TNF-α, compared to silymarin. In parallel, the histopathological profile in the mice` liver also proved that extract markedly minimized the PA toxicity and maintained the liver tissues` histoarchitecture to near the normal ones more than that achieved by silymarin.

Conclusion: The findings suggested that C. speciosus extract acts as a potential hepatoprotective agent against PA-induced liver toxicity. This hepato-protection effect may be due to the existence of steroids, saponins, different glycosides, and phenolic compounds in C. speciosus.
Tardive dyskinesia and dexmedetomidine
Authors: Palmer James
Published: February 2018

A 52‐year‐old female patient presented for a caudal epidurogram and epidural steroid injection. Patient compliance was limited by severe tardive dyskinesia secondary to previous chlorpromazine treatment. Based on a report of effectiveness in propofol‐induced dyskinesias, an infusion of dexmedetomidine was used which effectively controlled the movements within a few minutes. The patient remained alert and comfortable throughout. This report highlights the pharmacology and clinical application of dexmedetomidine in this clinical scenario, and proposes potential mechanisms underlying this therapeutic effect.
Delayed delivery of the two remaining fetuses of triplet pregnancy: Case Report
Authors: Abdelazim Ibrahim A. , Al-Munaifi Sulaiman
Published: February 2018

The incidence of multiple gestations increased after introduction of assisted reproduction techniques. Traditionally; in twin and/or triplet pregnancies; if one baby delivered preterm, this situation managed by delivery of the second and/or the third fetuses. This case report represents the suggested conservative management during the delayed delivery of the two remaining fetuses of triplet pregnancy, its outcome, and benefits.The studied woman is 35-years old, G3 P2, triplet pregnancy after intra-cytoplasmic sperm injection trial, presented with preterm premature rupture of membranes of the first fetus at 20+2 weeks` gestation, who delivered as fresh still birth. The couple informed, and agreed for the conservative management of the two remaining fetuses. After delivery of the first fetus; the umbilical cord ligated as high as possible in the cervix. She received systemic antibiotics for one week, with follow up of; infections, and consumptive coagulopathy parameters, and wellbeing of the fetuses through the conservative treatment. She received betamethasone to accelerate the lung maturity, and Mg-Sulphate for fetal neuro-protection at 24 weeks. The conservative management discontinued, and she delivered by cesarean section at 25 weeks+1 after attack of ante-partum hemorrhage. The delivered neonates admitted to neonatal intensive care unit on ventilator support, surfactant therapy, and antibiotics. 80 days after neonatal intensive care unit admission; the neonates discharged from the neonatal intensive care unit with corrected age of 36 weeks+, on complete oral feeding, and room air. The first fetus delivered at 20 weeks+2, fresh still birth (410 g), while the second, and third fetuses delivered at 25 weeks+1 (34 days of the conservative management), 780, and 840 g; respectively. Both fetuses survived, discharged from the neonatal intensive care unit after 80 days, at 2.2, and 2.3 kg weight; respectively. The birth weight, and the survival rate of both fetuses increased after the conservative management. The suggested conservative management of the delayed delivery may be associated with reduced neonatal mortalities without any maternal complications.
Uso de simulação no ensino de urgência e emergência pré-hospitalar para discentes de medicina: Relato de experiência
Authors: Chaves Guedes Mario Henrique , Sousa Gomes Jéssica Teles , De Almeida Andréia Santos Rezende De Almeida Santos Rezende , Lima Bonfim André Luiz Dias , Furtado Vilela Luiz Felipe , Côrtes Paula Pitta de Resende
Published: February 2018

As situações de emergência requerem intervenção imediata, de forma objetiva e eficaz, de modo a reduzir as possíveis sequelas e aumentar a sobrevida das vítimas. Por esse motivo, a ONG Projeto Vidas, composta por alunos do curso de Medicina da Universidade Severino Sombra, através do ensino por simulações, promove oportunidades para aquisição de habilidades cognitivas e psicomotoras de forma integrada nos seus cursos de primeiros socorros, permitindo aos estudantes a análise de seus desempenhos e autorreflexões. O objetivo deste estudo é relatar a experiência de um curso realizado por integrantes da ONG Projeto Vidas, com duração de 8 dias, com aulas expositivas e dinâmicas com simulações de atendimento, abordando diversos temas de pré-hospitalar. Ao início do curso, foi aplicado um pré-teste para a verificação do conhecimento prévio em situações de urgência e emergência. Ao final, foi realizado um grande simulado com múltiplas vítimas, onde os alunos tiveram a oportunidade de testar seus conhecimentos e sua capacidade técnica. Foi feito um pós-teste para avaliarmos o crescimento pedagógico e prático dos alunos, onde verificamos uma melhora de 64% no seu desempenho. Sendo assim, concluímos que esta significativa melhora das equipes ao final do simulado e ao final do pós-teste, demonstraram a relevância do ensino através de simulações para sedimentação de seu conhecimento, reforçando que o estudante de medicina deve ser inserido precocemente em simulações para garantir a conexão dos conhecimentos teórico-práticos e sua aplicação em situações reais.
Esofagite Eosinofílica: Relato de Caso
Authors: De Faria Gisele Euzébio , Ferraz Adriana Rodrigues
Published: February 2018

Esofagite eosinofílica é caracterizada por infiltrado de eosinófilos na mucosa esofágica que pode ocasionar modificações estruturais. Este trabalho objetiva relatar um caso de esofagite eosinofílica e sua evolução com o tratamento. Ressaltamos a importância do diagnóstico precoce e melhor qualidade de vida a partir do tratamento instituído. Mulher com queixa de dor torácica em opressão e impactação de alimentos sólidos. História pessoal de atopia. Endoscopia digestiva alta e biópsias evidenciaram quadro compatível com esofagite eosinofílica. Após um ano de tratamento, sem critérios para doença e com regressão do quadro. É uma doença associada à patogenia imuno-alérgica. Nos adultos é comum disfagia, pirose e impactação alimentar. O diagnóstico é feito por endoscopia digestiva e biópsia com mais de 15 eosinófilos/campo. É importante alertar a população médica para o conhecimento da doença e seus diagnósticos diferenciais. A terapêutica oferece melhor qualidade de vida e menor risco de infiltração eosinofílica da mucosa esofágica.
Medicamentos de uso prevalente pela população assistida por um projeto de extensão universitária
Authors: Souza Natália Avila , Cardoso Luísa Fernandes Rivelli , Souza Maria Cristina Almeida
Published: February 2018

A Universidade Severino Sombra, em Vassouras, no Estado do Rio de Janeiro, desenvolve projetos de extensão que contribuem positivamente para a qualidade de vida da população. Entre as ações de extensão universitária, destacam-se as viabilizadas pelo projeto Ipiranga, por meio do qual os alunos realizam ações de promoção em saúde e prevenção às doenças, bem como atividades assistenciais relacionadas ao primeiro nível de atenção à saúde. Entre as ações realizadas pelos alunos, inclui-se a pesquisa sobre os medicamentos mais utilizados pelos moradores participantes do projeto, correlacionando seus resultados à prevalência de agravos. O objetivo deste estudo é verificar os medicamentos de uso prevalente pela população assistida pelo projeto Ipiranga. Trata-se de uma pesquisa observacional e transversal, cuja coleta de dados foi realizada durante os meses entre setembro de 2016 e abril de 2017, por meio de um questionário estruturado contendo 7questões objetivas. A amostra foi composta por 34 pessoas, das quais 65% eram do gênero feminino. A idade dos participantes variou de 11 a 85 anos. Os medicamentos de uso mais prevalente foram losartana potássica (42%), hidroclorotiazida (27%), metformina (19%) omeprazol (19%) e nifedipina (11%). Conforme evidenciado, a prevalência da utilização de medicamentos de uso contínuo entre os participantes deste estudo tem como principal indicação médica as doenças crônicas não transmissíveis, como a hipertensão arterial sistêmica e o diabetes mellitus. A maioria dos medicamentos utilizados por essa população, sobretudo aqueles de uso mais prevalente, consta na Relação Nacional de Medicamentos Essenciais (RENAME).
Apoiando a Oferta de Informações sobre Transporte Coletivo Rodoviário através de uma Ontologia
Authors: Júnior Luiz Geraldo Dos Santos , Pereira Anrafel Fernandes
Published: February 2018

As redes de transporte de coletivo são de extrema importância para as cidades, porque é a partir delas que ocorre uma definição no que se refere às alternativas de deslocamento disponíveis à população. Entretanto, existe ainda um grande déficit em relação às informações precisas a respeito desses transportes para a população, sendo muitas das vezes inexistentes e desatualizadas. Tudo isso, acaba ocasionando transtornos e dificuldades para as pessoas que necessitam utilizar o serviço. Neste trabalho foi investigado o uso de ontologia para representação do conhecimento sobre redes de transporte coletivo rodoviário. O uso de ontologia neste contexto tem por objetivo trazer mais semântica e apoiar a distribuição de informações acerca dos transportes coletivos em uma cidade. Para isso, uma ontologia denominada OTNet foi desenvolvida e é apresentada neste trabalho.
A GESTÃO DO EQUIPAMENTOS DE PROTEÇÃO INDIVIDUAL NA SEGURANÇA COMPORTAMENTAL
Authors: Velloso de Souza Gustavo Augusto , Braga Enilson , Arvellos Luis , De Carvalho José Thomaz
Published: February 2018

Resumo: Este trabalho buscou apresentar os equipamentos de proteção individual (EPI) na construção civil, onde a utilização do mesmo torna-se necessária cada vez mais para a saúde e segurança dos trabalhadores. A obrigatoriedade das empresas no cumprimento das leis relativas à Segurança e Medicina no Trabalho, trouxe preocupação em evitar acidentes ou doenças ocupacionais. As inovações tecnológicas e a disseminação de informações sobre prevenção destes riscos tornam-se decisivas para melhorar a qualidade de vida no ambiente de trabalho.Neste artigo foi apresentado os equipamentos de proteção individual (EPI) que podem neutralizar ou minimizar as doenças ocupacionais ou até mesmo evitar as lesões decorrentes dos acidentes. O estudo visa, a abordagem preventiva, onde os profissionais envolvidos na construção civil devem atuar de forma consciente, no que se refere a segurança no trabalho. Para que tal conscientização ocorra se faz necessário levar até profissionais treinamento e capacitação. O objetivo deste trabalho é obter conhecimento, por meio de revisão bibliográfica, no ambiente de trabalho na área da construção civil para que possa ser minimizado o risco de acidentes no trabalho, levando aos futuros leitores o conhecimento necessário dos equipamentos de proteção individual (EPI) no ambiente da construção civil. Desta forma foi desenvolver prevenção em relação aos acidentes, por meio da segurança comportamental através do 5S. Palavras-chave: normas regulamentadoras, segurança do trabalho, EPI, trabalho em altura e 5S.
Virtual Screening in Hepatitis B Virus Drug Discovery: Current Stateof- the-Art and Future Perspectives
Authors: Elmessaoudi-Idrissi Mohcine , Blondel Arnaud , Kettani Anass , Windisch Marc P. , Benjelloun Soumaya , Ezzikouri Sayeh
Published: February 2018

Hepatitis B Virus (HBV) is a major global health burden. Interferon alpha and nucleos(t)ide
analogues are currently the standard-of-care for chronic HBV infection. However, these antiviral agents
have limited efficacy and do not result in a sustained virological response in the majority of infected patients.
Virtual Screening (VS) strategies have now a strong impact on drug discovery, the strength of this
research field has been corroborated by recent contributions in the development of novel drug candidates
which are in clinical trials or which are already available in the clinics. In this context, different VS strategies
have been applied to HBV in order to discover novel inhibitors. In this review, we summarize the VS
efforts to identify and design novel HBV interventions. We believe that the combination of in silico and in
vitro tools can lead to faster validation of novel drug targets which could accelerate the HBV drug discovery
and development efforts.
Erythrocyte Associated Amyloid-β as Potential Biomarker to Diagnose Dementia
Authors: Lauriola Michele , Paroni Giulia , Ciccone Filomena , D`Onofrio Grazia , Cascavilla Leandro , Paris Francesco , Gravina Carolina , Urbano Maria , Seripa Davide , Greco Antonio
Published: February 2018

Background:

Although it is known that Alzheimer's disease (AD) is associated with the progressive
accumulation of amyloid β-peptide (Aβ) in the human brain, its pathogenic role has to be completely
clarified. Aβ moves from the bloodbrain barrier to the plasma and an increased Aβ production in
brain could be associated with higher Aβ concentrations in blood. A recent study has evaluated Aβ40
and Aβ42 levels in human red blood cells (RBCs) with evidence of agedependent higher Aβ concentration
in RBCs.

Objective:

The aim of the study was to investigate if erythrocyte associated Aβ (iAβ) levels could be
different in subjects affected by dementia in comparison with controls and according to the patient’s
cognitive impairment or different dementia subtypes.

Method:

To answer these questions we assessed iAβ40 and iAβ42 levels in 116 patients: 32 healthy
controls, 39 with diagnosis of vascular dementia (VaD), 14 mild cognitive impairment (MCI) and 31
AD.

Results:

In this population we found significant differences in iAβ42 between controls and cognitive
impaired patients. Moreover, iAβ42 significantly differed between dementia vs MCI. AD also showed
different iAβ42 levels as compared to VaD. Conversely, no differences were found for iAβ40. All the
analyses were adjusted for potential confounders like age, gender and Hb concentration. A direct correlation
between increasing iAβ42 concentration and the progression of the cognitive decline using the
MMSE score as continuous variable was also found.

Conclusion:

Our findings support the evidence that iAβ42 could be an instrument to early recognize
dementia and predict cognitive impairment.
PIB y población desde el periodo tardo colonial hasta 2014: el caso venezolano
Authors: Decorso Sicilia Giuseppe Bernardo
Published: February 2018

El objetivo de este trabajo es múltiple, en primer lugar, propone una serie de población de Venezuela de 1783 a 2015, empleando nuevas estimaciones para el periodo colonial, guerra de independencia e información del censo de 2011, también, se incluye un primer análisis acerca del impacto demográfico de las inmigraciones en el crecimiento de la población en el siglo xx. Por otra parte, se presenta una serie del pib para el periodo 1783-1829. Con la nueva serie de población y del pib se obtiene una serie histórica del producto y la población que abarca desde 1783 hasta el 2014.
Motyw eschatologiczny w rytach katechumenalnych i chrzcielnych na przykładzie homilii katechetycznych Teodora z Mopsuestii
Authors: Grzywa Anna
Published: February 2018

Motyw eschatologiczny, choć nie znajduje się na pierwszym planie teologii chrzcielnej, to jednak zajmuje w niej istotne miejsce. Odwoływano się do niego zarówno w rytach katechumenalnych, jak i podczas celebracji chrzcielnej. Omawiany motyw spotykamy szczególnie często w pouczeniach katechetycznych Teodora z Mopsuestii (350–428), w których tłumaczy on przebieg oraz teologię sakramentu chrztu i Eucharystii. Artykuł przytacza najważniejsze elementy tego nauczania i wskazuje momenty w celebracji, gdzie elementy eschatologiczne wydają się być wyjątkowo podkreślane, próbując przy tym pytać o przyczynę podobnej praktyki.
Postoperative Home Monitoring After Joint Replacement: Retrospective Outcome Study Comparing Cases With Matched Historical Controls (Preprint)
Authors: Yang Homer , Dervin Geoff , Madden Susan , Fayad Ashraf , Beaulé Paul , Gagné Sylvain , Crossan Mary Lou , Wheeler Kathryn , Afagh Melody , Zhang Tinghua , Taljaard Monica
Published: February 2018

BACKGROUND

A retrospective cohort study was conducted in patients undergoing postoperative home monitoring (POHM) following elective primary hip or knee replacements.

OBJECTIVE

The objectives of our study were to compare the cost per patient, readmissions rate, emergency room visits, and mortality within 30 days to the historical standard of care using descriptive analysis.

METHODS

After Research Ethics Board approval, patients who were enrolled and had completed a POHM study were individually matched to historical controls by age, American Society of Anesthesiology class, and procedure at a ratio 1:2.

RESULTS

A total of 54 patients in the study group and 107 in the control group were eligible for the analysis. Compared with the historical standard of care, the average cost per case was Can $5826.32 (SD 1418.89) in the POHM group and Can $9198.58 (SD 1513.59) for controls. After 30 days, there were 2 emergency room visits (3.7%) and 0 readmissions in the POHM group, whereas there were 8 emergency room visits (7.5%) and 2 readmissions (1.9%) in the control group. No mortalities occurred in either group.

CONCLUSIONS

The POHM study offers an early hospital discharge pathway for elective hip and knee procedures at a 38% reduction of the standard of care cost. The multidisciplinary transitional POHM team may provide a reliable forum to minimize readmissions, and emergency room visits within 30 days postoperatively.

CLINICALTRIAL

ClinicalTrials.gov NCT02143232; https://clinicaltrials.gov/ct2/show/NCT02143232 (Archived by WebCite at http://www.webcitation.org/73WQ9QR6P)
How transformational leadership influences employee voice behavior: The roles of psychological capital and organizational identification
Authors: Wang Yanfei , Zheng Yangliu , Zhu Yu
Published: February 2018

We proposed a model with which we jointly tested psychological capital (PsyCap) as the key psychological mechanism through which transformational leadership (TL) affects employee voice behavior (VB), and examined the moderating effect of employees' organizational identification (OI)
on the PsyCap–VB relationship. Data were collected from employees in companies located in southern China and a small group of Master of Business Administration students who were also in paid employment (N = 237). Results showed that PsyCap fully mediated the TL–VB relationship,
and that the effect of PsyCap on VB would be stronger when OI was high than when it was low. Both theoretical and practical implications of the study are discussed, as well as limitations and future directions for research.
A Laminated Ring on Elastic Foundation Model and a Feedback Contact Algorithm for Tire-Road Contact Analysis
Authors: Wang Chunjian , Ayalew Beshah , Rhyne Timothy , Cron Steve , Adcox John
Published: February 2018

This article proposes (1) a two-dimensional tire model that extends the deformable ring on elastic foundation (REF) model by treating the ring as a laminated beam and (2) a feedback compensation approach to solve the tire-road contact problem as facilitated by the laminated REF model. The internal layer of the laminated ring is formulated using the Timoshenko beam theory that can also be easily regressed to an Euler beam. The external layer of the laminated ring is modeled as a circular beam that primarily takes into account the strain energy contributed by the tire tread in the transverse or radial direction. The elastic foundations are assumed to have a predeformation in the radial direction, which can model tire inflation pressure in pneumatic tires or foundation precompression/pretension for nonpneumatic tires. The analytical solution for the static deformation response of this laminated REF model due to an arbitrary external force is detailed first. Then, a feedback p-controller algorithm that penalizes geometry errors in the contact region is outlined as a unified approach that can be used to solve frictionless contact problems between a tire and arbitrary road profiles. The performances of the proposed model and algorithm are compared against those obtained from a detailed finite element analysis. Both flat surface and cleat contact responses are shown to illustrate the utility of this laminated REF model and the contact algorithm.
Respons Khalayak terhadap Vandyke Brown Print
Authors: And Edial Rusli Irwandi
Published: February 2018

This article discusses the forms of old print socialization to the community through the implementation of promotional mix method. The efforts were made to encourage the demand for old print products effectively to potential target audiences as well as looking for markets that form the foundation needs to be prepared. Print method that socialized is vandyke brown print. This method, based on the SWOT analysis is potentially the largest to be marketed to the public. The activites of promotional mix in this research are socialization, recruitment, workshop for potential stakeholders, such as photography business, Student Activity Unit, photography community, and high school students / vocational and promotion in various media. The result of socialization through the promotional mix shows that the target audience wants utilize old photographic print in their activities. They want to be able to do their own old printing process the print, the constraint is plagued with expensive materials. It cannot be purchased in retail. Audience response in this study should be followed by opening a new market space for the old print in Indonesia. One of the the new market here is old print service print services print and sales of chemical and materials to print with the old method of print.
Are You Sure You Have a Strategy
Authors: Kholid Arif Rozaq Muhammad
Published: February 2018

Tujuan tulisan ini adalah untuk mendiskusikan alternatif dalam prosesformulasi strategi. Seniman dalam menghadapi era industri kreatif tentunya membutuhkan strategi tertentu. terutama konsep dasar dalam formulasi strategi pada tingkat strategi bisnis, khususnya dalam industri kreatif. Telaah literatur menitikberatkan pada pendekatan strategi, apakah menggunakan strategi darurat (emergent strategy) atau strategi yang terartikulasi (deliberate strategy), atau campuran keduanya. Tulisan menawarkan salah satu pendekatan formulasi yang dikemukakan oleh Hambrick dan Fredrickson, 2001 yang dikenal dengan istilah Strategic Diamonds. Sebuah simpulan mengindikasikan bahwa Strategic Diamonds (Hambrick, 2001) sangat berguna dalam mengindentifikasi apa sebenarnya yang menjadi inti dari sebuah strategi. Elemen-elemen dari Strategic Diamonds dapat dipertimbangkan sebagai “penghubung” atau “titik pusat” dalam merancang sebuah sistem yang komprehensif dan terintegrasi. Tulisan ini mengusulkan kepada pelaku bisnis atau seniman untuk  engartikulasikan strategi secara jelas (deliberate view), dan mengikuti Lima Elemen yang dikenal dengan Strategic Diamonds: arena, vehicles, differentiators, staging and economic logic sebagai inti dari penyusun sebuah strategi.
Bollywood Influence to Indonesia (A Study through Television Media and Hibridity)
Authors: Mustikawati Retno
Published: February 2018

Bollywood adalah sebuah bagian dari kebudayaan populer yang sangat kuat bukan saja India, melainkan juga Timur Tengah, Negara bagian Afrika, dan sebagian negara Asia Tenggara. Penggunaan lagu dan musik seperti sebuah bahasa dalam film-film India dan menjadi salah satu pendongkrak popularitas sekaligus pembentuk film-film Bollywood. Perkembangan sinema Hindi dengan disertai sekuen-sekuan lagu-lagu dan tarian menjadi pembeda utama antara film-film yang lain. Terdapat sebuah hubungan yang dekat antara musik dangdut Indonesia dan musik yang berasal dari India. Musikdangdut adalah hibriditas dari musik India.
Angle Kamera Subjektif dalam Film “Aku Ada”
Authors: Rakhman Hakim Latief
Published: February 2018

While watching a movie, the viewers sometimes are get involved to thescreen. The viewers can feel the emotion described in a scene. This is happened due to the projection and imaginary identification processes. The viewers feel as if they have taken part to the scene. However the viewers just passively involved, there is no interaction between the actors/characters and the viewers.A subjective camera angle is the way to invite the viewers to get involvedin the scenes of ‘Aku Ada’ movie. The viewers interact with the actors on that movie through an angle’s point of view variation. The viewers can change the specific actor’s point of view in watching some different events, objects and settings in a scene. Their point of view can also be moved from a certain actor to the other actors, but how if the viewers cannot identify themselves to the movie.This of course can destroy the narrative structure and blur the message delivered by the movie.The originality of the movie “Aku Ada” is to place the viewers to thescenes through a subjective camera angle on the overall shots, and suddenly move the point of view from a certain actor to the others. The viewers will in turn change in involving the act of one actor with the others. This changing of sudden point of view are not be done by the previous movies to be a reference. The application of subjective camera angle in the movie “Aku Ada” can built up the viewer’s interaction to the scenes on the movie. They can project themselves on the movie scenes and can identify themselves to be involved in the movie “Aku Ada” through interaction or eye-contact with the characters on the movie.