bluuebunny/crossref_metadata_2025 huggingface dataset:
The possibilities of using PET on a mouse model of parkinsonism
Authors:   Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Savinkova E. V. , Zavadskiy S. P. ,   Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)
Published: December 2023

Parkinson's disease is a chronic degenerative progressive disease associated primarily with the death of neurons in the substantia nigra and other brain structures. The main symptoms are hypokinesia, rigidity, rest tremor, postural instability, as well as other autonomic and mental disorders. The prevalence of Parkinson's disease is 0.15 %; this figure reaches 1 % for people over 60 years of age. Ten years after the onset of the disease, 65 % of patients become disabled. The average life expectancy of patients is 9 years. Diagnosis of Parkinson's disease is carried out mainly by clinical manifestations, which begin when more than half of the dopaminergic neurons are already damaged. Before that, various compensatory mechanisms are still working, but over time their action ceases to be sufficient. Therefore, a crucial area in medicine is the early diagnosis of Parkinson»s disease. This is possible using functional imaging methods such as PET, SPECT, CT, and MRS. These methods allow detecting even the slightest changes in the structure and functioning of the brain and assessing the integrity of neurons and dopaminergic pathways. The paper presents the possibility of using PET imaging to determine the degree of degeneration of brain structures in a mouse model of MPTP-induced parkinsonian syndrome.
Fluorescent proteins in optical imaging
Authors:   Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Peshkova Ya. A. , Zavadsky S. P. ,   Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)
Published: December 2023

Optical bioimaging technologies, including fluorescence microscopy, which have been actively developing in recent years, have made it possible to visualize many biological processes. One of the most important tools for studying cellular and tissue structures are fluorescent markers, which allow monitoring structures or processes in real time. The authors have conducted a review study of the described fluorescent proteins and their areas of application, and made conclusions about the prospects for their use.
Safety of rivaroxaban in elderly patients
Authors:   Federal State Autonomous Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation, Shnaider K. O. , Kondrakhin A. P. ,   Federal State Autonomous Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation,   Moscow Healthcare Department,   State Budgetary Healthcare Institution of Moscow «Hospital for War Veterans No. 2 of the Moscow Healthcare Department», Maksimov M. L. ,   Federal State Autonomous Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation,   Federal State Budgetary Educational Institution of Continuing Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Health of the Russian Federation,   Kazan State Medical Academy — Branch Campus of the Federal State Budgetary Educational Institution of Continuing Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Health of the Russian Federation, Martynova S. A. ,   Federal State Autonomous Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation
Published: December 2023

Diseases associated with blood clotting disorders are one of the most common problems of a modern person and, accordingly, of the attending physician. Since rivaroxaban is a frequently prescribed drug in elderly patients for the treatment of thrombosis and prevention of stroke and embolism, the practitioner needs to be aware of the pharmacological properties and safety of rivaroxaban. This article provides updated information on the safety of rivaroxaban in elderly patients. We identified potentially relevant studies by searching the electronic databases MEDLINE, Scopus, PubMed, Google Scholar, and the Cochrane Database of Systematic Reviews from January 2020 to November 2023, using the terms: rivaroxaban, anticoagulants, thrombosis, stroke, embolism, elderly people, old age, therapy, safety, efficacy, adverse effects, clinical trials. Then, according to the inclusion and exclusion criteria, as well as by means of independent selection, all the authors of this article selected the sources meeting the criteria and compiled this review.
The importance of dynamic assessment of type 2 diabetes mellitus and its complications in patients of different age groups and clinical data monitoring
Authors:   FBHI Privolzhsky District Medical Center of the FMBA of Russia, Fabrichnaya L. I. , Khudyakova E. M. ,   Privolzhsky Research Medical University
Published: December 2023

The authors present the results of an analysis of the incidence rates of type 2 diabetes mellitus in the city of Nizhny Novgorod for 2018–2022, and identify the main changes for this period. The paper analyzes the data on the incidence and frequency of complications of type 2 diabetes mellitus with kidney damage, peripheral circulatory disorders, neurological complications, and multiple and unspecified complications, depending on the age and duration of the disease of patient
New prospects in the treatment of HIV infection: results of clinical trials of drugs
Authors:   Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Abdullaeva S. R. , Zavadskiy S. P. ,   Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)
Published: December 2023

HIV infection is one of the most dangerous and widespread infectious diseases in the world. According to the latest update from the Joint United Nations Program on HIV/AIDS, as of 2021, the number of people living with HIV infection was 38.4 million, and the number of new infections reached 1.5 million. [1] In Russia, according to Rosstat, the incidence of HIV infection increased by more than 20 % in January 2023, compared to January 2022. This means that the problem of HIV infection is still relevant, and additional efforts are required to combat this disease. Due to the development of medicine and pharmacology, new prospects have now emerged in the treatment of HIV infections. This paper examines the results of clinical trials of drugs that open up new opportunities in the fight against HIV infection. The authors set out to examine the latest advances in the treatment of HIV infection based on the results of clinical drug trials over the past 5 years.
National security and the international regime of foreign direct investment: modern challenges and prospects
Authors:   Primakov National Research Institute of World Economy and International Relations of Russian Academy of Sciences (IMEMO RAS), Moscow, Makarova A. A.
Published: December 2023

The study focuses on current developments in the foreign direct investment (FDI) regime, with an increasingly monitored approach to understanding FDI as a threat to national security. The research methodology is based on general scientifi c approaches; methods of analysis and synthesis used, comparison. Quantitative estimates are based on statistical data from international organizations. It is shown that the number of countries at the state level resorting to the concept of national security to limit the influx of unwanted FDI is growing. It is concluded that the barriers introduced will have a negative impact on future FDI dynamics. The danger of the emergence of strange controls over outgoing FDI, which today, in addition to the United States, is actively discussed in the European Union, since extraterritorial control of a country/group of countries creates even greater uncertainty and will signifi cantly aff ect the fl ow of FDI. More and more countries are opening their states into a new national security paradigm. Overall, this trend will only increase in momentum, which means the spread of special regimes for FDI. While protecting national interests is generally the "intent of existing frameworks" of national foreign investment regimes, further securitization, and the targeting of FDI to economic categories makes harmonization of rulemaking in this area much more difficult. However, reform of the approaches set out in BITs is necessary, since "outdated" treaties do not consider many aspects related to the current technological progress agenda. In the search for a new balance between national interests and the benefits of international cooperation, both regulatory global institutions and integration associations remain important.
Role of Cooperation in the Providing of Rural Population Employment: International Experience
Authors:   Ural State Agrarian University (USAU), Ekaterinburg, Golovina S. G. , Ruchkin A. V. ,   Ural State Agrarian University (USAU), Ekaterinburg
Published: December 2023

The transformation of the operating conditions of rural cooperatives, which has significantly changed the models and other aspects of their activities, affects not only their own results (directions of economic activity, revenue, income, geography of distribution of products and services), but also the livelihoods of the rural communities related to them (employment, supply of goods and services, meeting infrastructure and ecosystem needs). Serious environmental fl uctuations observed in rural areas recently are due, firstly, to the negative consequences of the COVID-19 pandemic, secondly, to natural anomalies caused by unfavorable climate change, and thirdly, to the negative eff ects of the aggravated geopolitical situation. In such a situation, in order to ensure territorial security, overcome threats of an economic, social, environmental nature, it is relevant to specify such forms of economic activity organizing that have the resources and potential not only to maintain the viability of the organization itself, but also to actively participate in solving difficulties and problems arising in the countryside. International practice in the development of cooperation during the coronavirus crisis and currently demonstrates that it may be rural cooperatives, adopting various organizational models (from the simplest to modern) and introducing all kinds of innovations, that are capable of becoming key "players" in rural areas, complementing or even replacing structures that have left for objective reasons their territories (commercial organizations, government agencies). In this article, in this regard, some research results are presented regarding the possibilities of rural (including agricultural) cooperatives to expand the range of their multifunctional activities, to attract representatives of various agricultural and non-agricultural professions to their members and employees, thereby ensuring decent employment and income for the villagers. The theoretical basis of the undertaken research was made up of modern scientific publications, which were the result of increased interest among scientists in new cooperative practices and the adaptability of existing cooperatives to emerging risks and threats. In turn, the empirical basis was provided by numerous examples of rural cooperatives functioning in some countries of the world, in which, despite differences in the environment, the conditions for the rural cooperation development have changed significantly.
Increasing Information Transparency of the Results of a Regional Export Project in the Urals Federal District
Authors:   Institute of Economics of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Glukhikh P. L.
Published: December 2023

The influence of information on the activities of the authorities is increasing. The problem of the low popularity of the national project "International Cooperation and Export" remains. The purpose of the article is to generalize the theory and develop a methodology for assessing the information transparency of the results of the regional project "Systemic measures for the development of international cooperation and exports" of the regions of the Ural Federal District and to develop applied recommendations. The author has developed signs of information transparency: relevance (relevance, focus, timeliness),sufficiency (completeness, structuring) of information. A program of research and methodological tools for score assessment based on content analysis of government websites and open sources has been developed. The applied signifi cance lies in the systematization of the economic practice of information transparency in the regions of the Ural Federal District. The most significant problem is the lack of linking information with the approved project results. The value of the information relevance subindex (from 0.11 points in the Kurgan Region to 2.50 points in the Tyumen Region) and the information sufficiency subindex (from 0.02 points in the Sverdlovsk Region to 2.22 points in the Khanty-Mansi Autonomous Okrug) were calculated. Practical recommendations have been developed for the authorities: relevance and focus, reliability of information, comparability of planned and actual values, structuring and detailing of information. The obtained principles of information relevance can be used as a basis for the development of appropriate standards for the provision of information.
Exfoliate cancer cell analysis in rectal cancer surgery: comparison of laparoscopic and transanal total mesorectal excision, a pilot study
Authors: You Kiho , Hwang Jung-Ah , Sohn Dae Kyung , Lee Dong Woon , Park Sung Sil , Han Kyung Su , Hong Chang Won , Kim Bun , Kim Byung Chang , Park Sung Chan , Oh Jae Hwan
Published: December 2023

Purpose: Minimally invasive surgery (MIS) is currently the standard treatment for rectal cancer. However, its limitations include complications and incomplete total mesorectal resection (TME) due to anatomical features and technical difficulties. Transanal TME (TaTME) has been practiced since 2010 to improve this, but there is a risk of local recurrence and intra-abdominal contamination. We aimed to analyze samples obtained through lavage to compare laparoscopic TME (LapTME) and TaTME.Methods: From June 2020 to January 2021, 20 patients with rectal cancer undergoing MIS were consecutively and prospectively recruited. Samples were collected at the start of surgery, immediately after TME, and after irrigation. The samples were analyzed for carcinoembryonic antigen (CEA) and cytokeratin 20 (CK20) through a quantitative real-time polymerase chain reaction. The primary outcome was to compare the detected amounts of CEA and CK20 immediately after TME between the surgical methods.Results: Among the 20 patients, 13 underwent LapTME and 7 underwent TaTME. Tumor location was lower in TaTME (7.3 cm vs. 4.6 cm, P=0.012), and negative mesorectal fascia (MRF) was more in LapTME (76.9% vs. 28.6%, P=0.044). CEA and CK20 levels were high in 3 patients (42.9%) only in TaTME. There was 1 case of T4 with incomplete purse-string suture and 1 case of positive MRF with dissection failure. All patients were followed up for an average of 32.5 months without local recurrence.Conclusion: CEA and CK20 levels were high only in TaTME and were related to tumor factors or intraoperative events. However, whether the detection amount is clinically related to local recurrence remains unclear.
PENINGKATAN KETERATURAN PEMERIKSAAN KEHAMILAN DENGAN MENINGKATNYA PENGETAHUAN IBU HAMIL TENTANG TANDA BAHAYA KEHAMILAN TRIMESTER III
Authors: Melanie Astuti Setiawan Shellita , Lucyati Alma , Rachmadhiani Ira Dewi
Published: December 2023

Kehamilan pada trimester III sering disebut sebagai “fase penantian” yang penuh kewaspadaan. Angka Kematian Ibu (AKI) masih belum mencapai target yang ditentukan yaitu 183 per 100.000 KH. Tujuan penelitian ini untuk mengetahui hubungan peningkatan keteraturan pemeriksaan kehamilan dengan meningkatnya pengetahuan ibu hamil tentang tanda bahaya kehamilan trimester III. Desain penelitian ini analitik observasional. Sampel penelitian berjumlah 40 orang yang dipilih dengan teknik total sampling. Data diambil menggunakan kuesioner yang sudah divalidasi dan di uji reliabilitas. Analisa data menggunakan distribusi frekuensi dan uji Chi Square. Hasil dari penelitian diketahui bahwa mayoritas ibu berpengetahuan baik dengan persentase sebesar 47,5%. Hasil keteraturan pemeriksaan kehamilan ibu yang teratur 55% dan yang tidak teratur 45%. Terdapat hubungan yang signifikan antara tingkat pengetahuan dengan keteraturan pemeriksaan kehamilan tentang tanda bahaya kehamilan trimester III. Dapat disimpulkan bahwa terdapat hubungan antara tingkat pengetahuan dengan keteraturan pemeriksaan ibu hamil tentang tanda bahaya kehamilan di trimester III. Dari hasil penelitian ini dapat menambah wawasan dan informasi bahan kajian pengetahuan yang berkaitan dengan tanda bahaya kehamilan di trimester III pada ibu hamil.
Üretici Dönüşümsel Dilbilgisi Kuramına Göre Cümle Kurucuların İşlevleri
Authors: GÜRKAN Duygu Özge
Published: December 2023

Sözdizim, temel dilbilgisi bileşenlerinden biridir. Bugün farklı dilbilgisi kuram ve

yöntemlerinin uygulandığı çok sayıda sözdizim çalışması mevcuttur. Bunların kimisi yapısal

özelliklere odaklanırken kimisi yapısal özelliklerin yanı sıra anlamsal, işlevsel ya da edimsel

özelliklere odaklanmaktadır. Yine de bütün bu çalışmaların ortak noktası sözdizimin

dillerdeki cümle görünümlerini inceliyor olmasıdır. Bu çalışmanın metodolojisi

Chomsky’nin sözdizim kuramına dayanmaktadır. Bu kuram temelde sonlu sayıda kuralla

sonsuz sayıda cümle üretilebileceğini açıklamayı hedeflemektedir. Kurucular ise cümle

içerisinde tek bir birim gibi işlev gören sözcük gruplarıdır. Kurucular cümle içerisinde

hiyerarşik bir ilişkiyle birbirlerine bağlanırlar. Hiyerarşik kurucu ilişkileri ve bunlara dair

kurallar da ağaç diyagramını oluşturur. Bu çalışma sözdizim kuramı doğrultusunda söz

konusu kurucuların kategorileri ve işlevleri üzerinedir. Cümledeki her bir kurucunun ad

öbeği, eylem öbeği gibi bir kategorisi ve özne, yüklem gibi bir sözdizimsel işlevi vardır. Bu

çalışma, hiyerarşik kurucu ilişkileri temel alınarak Türkçe sözdiziminin genel yapısını ortaya

koymaya yöneliktir. Ancak Türkçe sözdizimi çok kapsamlı bir konu olduğundan, burada, bu

konu, sözdizim kuramının temel kavramlarını oluşturan baş (öbek kurucu), başın öbek

oluşturmak için yanına aldığı tümleç, eklenti gibi üyeler ve bunlar arasındaki sözdizimsel-işlevsel ilişkiyle sınırlandırılmıştır.
Kutsal Kitaplarda Seyahat ve Rehberlik Üzerine Bir İnceleme
Authors: KAYA Selim
Published: December 2023

Amaç ve Önem: Bu çalışma sosyal hayatın temel dinamiklerinden biri ve dini düşünce ve yaşamın belirleyicisi olan kutsal kitapların, seyahate bakış açısını ve ifade şeklini ele almak ve mukayeselerde bulunarak değerlendirmek amacıyla hazırlanmıştır. Seyahat kutsal kitaplarda var mı? Kutsal kitaplar gezmeyi, seyahati ve rehberliği önermiş mi? sorularına cevap bulmak ve seyahatin kutsal kitaplardaki panaromasını ortaya koymak, ayrıca üç farklı dinin inanç esaslarını belirten dört kutsal kitapta seyahat ve gezi ile ilgili bilgileri tespit etmek amaçlanmıştır. Çalışma, ulusal alan yazındaki seyahat konulu çalışmaların tarihsel süreçteki özellikle de orta çağdaki durumunu belirleme açısından önem taşımaktadır.

Yöntem: Çalışmada ihtiyaç duyulan verilerin elde edilmesinde ikincil veri analizi tekniği kullanılmıştır. Bu kapsamda dört semavi dinin kutsal kitabında yer alan metinler kodlar aracılığı ile incelenmiştir. Dört kutsal kitap çalışma verilerine dâhil edilmiştir.

Bulgular: Seyahatin ve rehberliğin amacı ve niteliği ile ilgili kutsal kitaplarda yönlendirici verilerin bulunduğu görülmektedir. Seyahat kavramının tarihi arka planının kutsal kitaplara dayandığı tespit edilmiştir. Kutsal kitaplardaki metinlerde gezinti yapmaya ve gezmeye ve seyahate ve rehberliğe yer verildiği, hatta Tevrat’ta “gezginler deresi” adıyla anılan bir yerin olduğu fark edilmiştir. Son zamanlarda önem kazanan kültürel gezilerin dini amaçlarla yapılan gezilerle bağlantılı olduğu, orta çağda hacı olmak için yapılan yolculuğun da seyahatin bir çeşidi olduğu anlaşılmıştır. Ayrıca inanılan dinin propagandasını yaparak yaymak için misyonerlik amaçlı seyahatlerin orta çağda yoğunlaştığı, zaman içinde çeşitlendiği ve parametrelerin farklılaştığı görülmüştür.

Özgünlük/Bilimsel Katkı: Bu çalışma seyahat fikrini ve uygulanışını kutsal kitaplarda bütüncül bir yaklaşımla ve mukayeseli olarak ele alan ilk çalışmadır. Çalışma; gezi, seyahat, gezgin, seyyah ve turist rehberliği kavramları ile ilgili çalışmalara katkı sağlama özelliğine sahiptir. Turist rehberliğinin orta çağ tarihine ve gelişim seyrine ışık tutan ilgili akademik çalışmaların azlığı sebebiyle araştırmanın, konu ile ilgilenenler için önemli olduğu ve literatüre katkı sağlayacağı düşünülmektedir. Çalışmanın turist rehberliği alanına yönelik araştırmalara, turizm ile ilgili bazı kavramlara, orta çağdaki gezi ve seyahatin niteliğine ve ilim âlemine bilimsel katkı sağlayacağı ümit edilmektedir.
Метод виявлення пошкоджень земної поверхні внаслідок воєнних дій за допомогою супутникових даних
Authors: Мікава Поліна Віталіївна , Дрозд Софія Юріївна
Published: December 2023

Місцевість, яка стала ареною активних воєнних дій, зазнає значних пошкоджень у результаті бойових зіткнень та артилерійських обстрілів. Зокрема, ураження родючих земель робить їх непридатними для використання. Внаслідок цього виникає і стає все більш нагальним питання відновлення територій. Сьогодні розробляється багато проєктів по відновленню як інфраструктури, так і самої земної поверхні. Значна частина таких проєктів ініціюється іноземними партнерами та активно підтримується ними фінансово. Створення ефективного механізму відновлення потребує актуальної інформації щодо площі та ступеня пошкоджень території. Через постійну загрозу обстрілів загальна безпекова ситуація в країні нестабільна, а більша частина пошкоджених територій розташована безпосередньо поруч з лінією фронту. З огляду на це актуальною є розробка методів аналізу земної поверхні, що базуються на інформації, отриманій віддалено. Одним з джерел такої інформації можуть бути дані місії Sentinel-2. У роботі розглянуто метод виявлення та аналізу пошкоджень території на основі розрахунків та порівнянь індексу рослинності NDVI. Інформація оцінюється протягом певного часового відрізку, розділеного на двотижневі періоди. Найпоширенішими серед пошкоджень виявилися воронки, утворені внаслідок обстрілів та вибухів, вигорілі поля та сліди військової техніки.
Buzzing Opportunities: Integrating Apitourism for Enriching the Tourism Heritage of the Republic of Benin
Authors: Amakpe Felicien , Graaf Dirk De , Sinsin Brice , Biaou Honore S.
Published: December 2023

Tourism is the third most crucial socio-economic sector that generates income and employment in the Republic of Benin, where it occupies a prominent place in the country’s development policies. In response to the sustainable development requirements, tourists are worldwide more and more demanding on the quality and diversity of the services they receive. As such, strengthening the tourism sector requires environmentally and socio-economically sustainable innovations. Bees, with their great ecological and socio-economic functions, offer many facets which can be valued to support the well-diversified tourism heritage of the Republic of Benin. This review analyses existing tourism heritage, the diversity of bees and apicultural practices in the country and their susceptibility to apitourism development. Tourism promotion strategies based on the products and the ecological services of social, and solitary bee species were analysed per suggested ecotourism region of the country. The involved actors, their roles, and responsibilities, as well as the challenges that may emerge from integrating the bee sector into the tourism heritage of the country, were also analysed.
“Timbre-Factor of Film Music”
Authors: Михеева Ю.В.
Published: December 2023

Целью статьи является актуализация темы тембра музыкального инструмента и певческого голоса в киномузыке. Вопросы тембральной специфики часто включаются в контекст работ, посвященных анализу музыки в ракурсе ее функций и семантики в аудиовизуальной структуре фильма, но, как правило, не рассматриваются обособленно. Однако развитие языка киноискусства и звукозаписывающих технологий приводят к пониманию необходимости специальных исследований возможностей тембров в современных музыкально-звуковых решениях кинофильмов. В статье дан краткий обзор историко-теоретических, технико-технологических и эстетических аспектов изучения тембра в киномузыке. На примере ряда кинопроизведений В. Вендерса, Дж. Джармуша, И. Бергмана, А. Балабанова, А. Каурисмяки и других режиссеров демонстрируется монотембральность как один из приемов выражения квинтэссенции авторской эстетики и глубинной семантики в звуковом решении фильма. Отдельное внимание обращается на относительно кратковременные включения му­зыкаль­ных фрагментов с характерным тембром внутри так называемых медитативных зон фильма. Другой рассматриваемый аспект поиска и применения тембров в современном кинематографе связан с новым осмыслением и аудиовизуальным воплощением диегетического и недиегетического пространств фильма в парадигме транскультурализма, а также в условиях развития многоканальных звуковых форматов, применяемых в кинопроизводстве начиная с 2010-х годов.

The article updates the topic of the timbre of a musical instrument and a singing voice in film music. Issues of timbral specificity are often included in the context of studies devoted to the analysis of film music from the perspective of its functions and semantics in the audiovisual structure of the film but, as a rule, are not considered separately. However, the development of the cinematographic language and sound recording technologies lead to an understanding of the need for special studies of timbre possibilities in the creation of modern musical and sound solutions in films of different genres. The article provides a brief overview of the historical-theoretical, technical-technological and aesthetic aspects of timbre study in film music. On the example of a number of films by W. Wenders, J. Jarmusch, I. Bergman, A. Balabanov, A. Kaurismäki and other directors, mono-timbre is demonstrated as one of the means for expressing the quintessence of the author’s aesthetics and the deep essence of the semantic utterance in the sound solution of the film. Special attention is paid to the relatively short-term inclusion of musical fragments with a characteristic timbre inside the so-called “meditative zones” of the film. Another spotlighted tendency in search and appli­cation of timbres in modern cinema is associated with a new understanding and audiovisual embodiment of the diegetic and non-diegetic spaces of the film in the transcultural paradigm and in the context of the development of multi-channel sound formats used in film production since the 2010s.
“Andrey Golovin: ‘I love to Live in Infinity’”
Authors: Маркина П.В.
Published: December 2023

В интервью с композитором, профессо­ром кафедры композиции Российской академии музыки имени Гнесиных Андреем Ивановичем Голо­виным идет речь о работе над его последними сочинениями и о премьере одного из них ― Sinfonia concertante для гобоя с оркестром, — которая прошла в зале «Зарядье» в ноябре 2022 года. В беседе подробно раскрывается процесс работы над произведением, его художественное и музыкальное содержание. Также затрагиваются вопросы техники музыкальной композиции; обсуждаются пути традиционализма и новаторства в современной академической музыке, проблемы творчества в целом. Кроме того, композитор делится в беседе своими литературными предпочтениями.

In the interview composer, professor of the Com­position Department of the Gnesins Russian Aca­demy of Music Andrey I. Go­lo­vin talks about the work on recent compositions and the premiere of “Sin­fonia concertante” for oboe and orchestra. The com­po­sition was performed in the Mos­cow concert hall “Zaryadye” in November 2022. The article discusses the compositional process, artistic and musical content of this opus. Also the interview spot­lights composi­tional techniques, traditionalism and innovation in con­tempo­rary music, and meaning of the creativity as a whole. In addition, the material contains a small conversation about Golovin’s literary preferences.
“Faradzh Karaev: ‘Almost All of Us Remain Soviet Composers, with Our Poverty and Fronde’”
Authors: Фархадов Р.Я.
Published: December 2023

Музыковед Рауф Фархадов взял интервью у композитора Фараджа Караева, приуроченное к его 80-летнему юбилею. Давние соратники по Ассоциа­ции современной музыки обсудили этапы творческого пути Караева, его личные и профессиональные взаимоотношения с отцом, композитором Кара Караевым. Фархадов выяснил, какой совет дал Фараджу Караеву Альфред Шнитке, как возник замысел Концерта для оркестра и скрипки соло, признанного одним из лучших сочинений автора, и что композитор взял бы с собой на необитаемый остров.

In a conversation with composer Faradzh Karaev on the occasion of his 80th birthday, musico­logist Rauf Farkhadov discussed the stages of Karaev’s creative path, personal and professional relationships with his father, composer Kara Karaev, found out what advice Alfred Schnittke gave to Faradzh Karaev, how the idea for the Concerto for Orchestra and Solo Violin, recognized as one of the author’s best works, and what the composer would take with him to a desert island.
Çelişik Olmayan Önermelerden Oluşan Bir Bilim Dili Arayışı: Gösterim Teorisinden Sonra Russell’ın Tanımlı Betimlemeler Teorisi ve Denotasyon Anlayışı
Authors: KIRMACI Hatice
Published: December 2023

Bilimsel bir dilin inşası için çelişik olmayan önermelerin araştırılması elzemdir. Nitekim Leibniz’den bu yana filozoflar, bilimin kullanımına uygun olan sembolik bir dil üretimi için çaba sarf etmişlerdir. Frege, her türlü akıl yürütme için genel bir cebir dilini kavram yazısıyla (Begriffsschrift) ortaya koymuştur. Önermedeki kavramın referansının hiçbir nesneye tekabül etmemesi yöntemimizi şekillendirmiş ve bizi, kaplamı boş olan kavramlar içeren önermelerin geçerliliği üzerine araştırma yapmaya, özellikle de Russell’ın tanımlı betimlemeler teorisine yönlendirmiştir. Bu makalede “Çelişik olmayan önermelerden oluşan bir bilim dili nasıl oluşturulabilir?” problematiğine çözüm olanağı bulmak amaçlanmaktadır. Araştırmamızın sonunda, Russell'ın tanımlı betimlemeler teorisinin, çelişik olmayan önermelerin gönderimi sayesinde çoğulcu bir formülasyona izin verdiğini ve söz konusu teorinin amaçlanan bilimsel bir dil için elverişli olduğunu tespit etmekteyiz.
Dermatoloji Polikliniğine Başvuran Gebelerde Gözlenen Deri Değişiklikleri ve Dermatozların Retrospektif Analizi
Authors: SUBAŞI GÖKŞİN Şule , İMREN Işıl Göğem
Published: December 2023

Amaç: Gebelikte endokrinolojik, vasküler veya immünolojik değişiklikler deride birçok farklı klinik duruma neden olabilir. Dermatoloji polikliniğine başvuran gebe hastalarda gözlenen deri değişiklikleri ve dermatozların klinik analizini yapmak.
Materyal ve metod: Çalışmaya Mart 2021 ile Eylül 2022 tarihleri arasında dermatoloji polikliniğine başvuran 112 gebe hasta dahil edildi.
Bulgular: Hastaların yaş ortalaması 28,8±6.9 (min.18-max.44) idi. Gebelerin %58'i primigravida, %42'si multigravida idi. Gebeler sıklıkla 2. ve 3. trimesterde polikliniğe başvurdu (78.6%). Olguların %82.1'inde fizyolojik deri değişiklikleri görüldü. En sık stria gravidarum %51.8, kloazma %9, variköz venler ve spider anjiyom %5.4, linea nigra, akrokordon, cherry anjiyom ve saç dökülmesi %2.7, hirsutizm ve tırnak batması %1.8, pyojenik granülom %0.9 olguda görüldü. Olguların %33,9'unda cilt infeksiyonu saptandı. Mantar infeksiyonları (Dermatofitoz %9, pitriyazis versikolor %3.6, kandida %3.6) %14.3 ile en sık, uyuz %11.6 ile ikinci sıklıkta görüldü. Gebeliğin atopik erüpsiyonu, pemfigoid gestasyonis ve impetigo herpetiformis gibi gebeliğe özgü dermatozlar olgularının %2,7'sinde görüldü. Gebeliğe özgü olmayan dermatolojik hastalık oranı %27.7 iken, bu hastalıklar içinde seboreik dermatit %9, psoriazis %6.2 akne ve rozasea ise %3.6 oranındaydı. Primigravidalarda ve üçüncü trimesterde pigment değişiklikleri, stria gravidarum ve gebeliğe özgü dermatozlar istatistiksel olarak anlamlı düzeyde yüksekti (p<0.05). Multigravidalarda ve üçüncü trimesterde tekrarlayan poliklinik başvurularının istatistiksel olarak anlamlı olduğu gözlendi (p<0.05).
Sonuç. Hamilelik sırasında en sık görülen deri değişikliği fizyolojik deri değişiklikleridir. Gebeliğe özgü dermatozlar nadir görülür. Gebelikte en sık görülen deri infeksiyonları mantar infeksiyonlarıdır. Üçüncü trimesterde deri değişiklikleri ve spesifik dermatozlar artar.
Implementation Of Islamic Education With Blended Learning Model In New Normal Era
Authors: Hayati Aulia Nur , Usriyah Lailatul
Published: December 2023

In the new normal era, educators seek to balance learners' safety and learning rights. However, because the quantity of learners in MIN 3 Banyuwangi is very much and they are required to comply with health protocols (primarily maintaining distance), the solution taken by MIN 3 Banyuwangi is implementing a blended learning model in teaching and learning activities (KBM). The focus of the problem in this study is the planning, implementation, and evaluation of Islamic education using the blended learning model. This study aims to determine the planning, implementation, and evaluation of learning using the combined learning model. Researchers use a descriptive qualitative approach to the type of case study. The data collection techniques use observation, interviews, and documentation. At the same time, the data analysis used is Miles, Huberman, and Saldana model data analysis consisting of data condensation, data display, and conclusion drawing/verification. Then, the validity of the data that researchers use is the source triangulation and triangulation techniques. This study obtained the following results: 1) MIN 3 Banyuwangi prepares learning scenarios and creates learning tools in planning activities. 2) in the implementation of learning, there are three activities: introduction, core, and closing. 3) as for learning evaluation, educators measure learners' learning outcomes from cognitive, affective, and psychomotor aspects through daily tasks, PTS, and PAS. In implementing PTS and PAS, MIN 3 Banyuwangi divided two groups. The upper class uses Computer-based Test mode, and the lower class uses paper and Pen mode. In addition, in the evaluation activities, the head of the madrasah has also reflected on the performance of educators by providing KBM journals and conducting socialization activities on "teacher performance assessment."
Implementation Of Multicultural Education Values In Islamic Boarding School
Authors: Wahyudi Aris , Mahfuds Yusqi , Machmud Wanda Saputri
Published: December 2023

Indonesia has a motto known as 'Bhineka Tunggal Ika'. This motto means although they are different but still one, this is because Indonesia has a diversity of tribes, cultures, races, and languages. The inability of some individuals in Indonesia to accept these differences leads to negative multiculturalism. In pesantren, this will be more sensitive because the students have a diversity of backgrounds both in terms of culture, ethnicity, ethnicity, language, and regions which are then united in the same place. Multicultural education is defined as education that teaches differences and the vitality of cultural diversity and ethnicity related to equality, justice, openness, and recognition of differences. This study aims to determine the inculcation of the value of multicultural education, especially at the Al-Fatah Islamic Boarding School, Temboro. This research is a descriptive qualitative using a phenomenological approach, which is a study that aims to objectively reveal facts, symptoms, and events related to the phenomenon of planting and values ​​of multicultural education at the Al-Fataah Islamic Boarding School, Temboro. This research is also included in the field research category. The results of the study found the inculcation of multicultural educational values ​​that emphasize the importance of legitimacy, and the vitality of ethnic and cultural diversity in shaping the order of life, groups, and nations by inculcating democratic values ​​to using strategies that involve approaches to parents.
Practical Implementation of An-Nahdliyah Method for Improving the Ability to Read the Qur'an in TPQ Roudlotuts Taallum
Authors: Subandono Agus , Saka Dijan Novia , Alim Bagus Muhamadin , Wulandari Desi , Rosidah Fatkhur
Published: December 2023

This research aims to assess the effectiveness of implementing the An-Nahdliyah method in enhancing Quran reading proficiency at TPQ Roudlotut Taallum. The study employs a qualitative field research approach to delve into the practical application of the An-Nahdliyah method, following the prescribed guidelines for managing Quran education centers. Various challenges are identified, including students' difficulties in comprehending learning materials, irregular attendance, and a lack of enthusiasm throughout the learning process. The findings of this study provide valuable insights into the efficacy of the An-Nahdliyah method and shed light on potential obstacles that may arise during its implementation.
Penelitian ini bertujuan untuk menilai efektivitas penerapan metode An-Nahdliyah dalam meningkatkan kemampuan membaca Al-Qur'an di TPQ Roudlotut Taallum. Penelitian ini menggunakan pendekatan penelitian lapangan kualitatif untuk menyelidiki implementasi praktis metode An-Nahdliyah, dengan mengikuti pedoman yang ditetapkan untuk pengelolaan pusat pendidikan Al-Qur'an. Beberapa tantangan yang diidentifikasi meliputi kesulitan yang dihadapi siswa dalam memahami materi pembelajaran, kehadiran yang tidak teratur, dan kurangnya antusiasme selama proses pembelajaran. Temuan penelitian ini memberikan wawasan tentang efektivitas metode An-Nahdliyah dan mengungkapkan hambatan potensial yang mungkin timbul selama implementasinya.
Optimasi Pembelajaran Kimia Melalui Peningkatan Pemahaman Bersama Dan Pendampingan Bagi Guru Mgmp Kimia dalam Implementasi Kurikulum Merdeka di Kabupaten Lumajang
Authors: Sutrisno Sutrisno , Munzil Munzil , Dasna I Wayan , Wijaya Husni Wahyu , Setiawan Nur Candra Eka
Published: December 2023

Artikel pengabdian ini bertujuan untuk mengoptimasi pembelajaran kimia melalui peningkatan pemahaman bersama dan pendampingan bagi para guru MGMP Kimia dalam implementasi kurikulum merdeka di Kabupaten Lumajang. Kurikulum merdeka memberikan kebebasan bagi guru dalam menyusun materi pembelajaran yang sesuai dengan kebutuhan dan potensi siswa. Namun, kendala seperti keterbatasan akses informasi, sarana, prasarana, dan minimnya kolaborasi antar guru dapat mempengaruhi kualitas pembelajaran kimia. Tim pengabdian Departemen Kimia FMIPA UM melakukan analisis kebutuhan dan tantangan yang dihadapi para guru MGMP Kimia Kabupaten Lumajang. Kegiatan ini dilaksanakan selama dua bulan. Berdasarkan hasil analisis, dilakukan program pendampingan dan pelatihan yang fokus pada pemahaman bersama tentang kurikulum merdeka dan penerapannya dalam pembelajaran kimia. Program ini melibatkan kegiatan pelatihan, diskusi, observasi, dan pemberian feedback yang berkesinambungan. Selain itu, tim pengabdian juga memberikan dukungan dalam menyusun dan mengoptimalkan sumber daya pembelajaran kimia. Sumber daya ini berupa modul pembelajaran, materi presentasi, dan bahan ajar interaktif lainnya yang dapat meningkatkan kreativitas dan efektivitas pembelajaran kimia. Hasil dari pelaksanaan program dievaluasi untuk mengukur dampak dan efektivitas kegiatan pengabdian. Artikel ini berharap dapat memberikan panduan bagi para pendidik dan peneliti untuk meningkatkan kualitas pendidikan kimia di Kabupaten Lumajang. Diharapkan, pengabdian ini dapat berkontribusi positif dalam mendukung pembangunan pendidikan yang lebih baik dan inovatif di daerah tersebut.
Pelatihan Pembuatan Gantungan Kunci dan Pin Bagi Santri Yayasan Ponpes Darul Khaer Praya Lombok Tengah dalam Mendukung Program Kewirausahaan
Authors: Pyo Munawarah  , Septika Baiq Herdina , Krisnahadi Tama , Supratman Supratman , Wulandari Yayang Erry
Published: December 2023

Kegiatan pengabdian kepada masyarakat ini dilaksanakan untuk memberikan kontribusi bekal Life Skill kepada peserta didik menjadi lebih siap mandiri serta menjadi insan yang produktif. Kegiatan ini dalam bentuk pelaksanaan program Pelatihan Pembuatan Gantungan Kunci dan Pin bagi Santri Yayasan Ponpes Darul Khair Praya Lombok Tengah dalam Mendukung Program Kewirausahaan. Mitra dalam kegiatan ini adalah peserta didik Ponpes Darul Khair yang berjumlah 30 orang. Pelaksanaan Kegiatan dalam tiga tahap, yaitu (1) tahap perencanaan, (2) tahap pelaksanaan, dan (3) tahap evaluasi.Hasil dari kegiatan ini adalah meningkatnya pengetahuan peserta didik hingga 100% terkait kemampuan menggunakan aplikasi Corel Draw dalam membuat desain gantungan kunci dan pin. Para peserta juga bisa mengoperasikan mesin press untuk mencetak gantungan kunci dan pin, selain itu peserta didik mampu menghasilkan karya yang berupa gantungan kunci dan pin.
Pemeriksaan Hewan Kurban di Musholla Al Atqiyah Karang Sukun Baru Kota Mataram
Authors: Kholik Kholik , Riwu Katty Hendriana Priscillia , Rahmawati Septyana Eka , Rusdiana Nur , Asmara Zinie Hikmah
Published: December 2023

Musholla Al-Atqiyah yang terletak di Kota Mataram setiap tahunnnya menyelenggarakan pemotongan hewan kurban sapi dan kambing. Pemotungan hewan kurban tersebut meminta bantuan dokter hewan di Fakultas Kedokteran Hewan Universitas Pendidikan Mandalika dalam pemeriksaan ante-mortem dan post-mortem. Tujuan kegiatan pemeriksaan kurban adalah untuk menghasilkan daging yang aman, sehat, utuh, dan halal sehingga memberikan jaminan rasa aman kepada masyarakat. Pemeriksaan ante-mortem terhadap hewan kurban sapi dan kambing dilakukan dengan pemeriksan fisik dan cara berjalan untuk melihat adanya gejala klinis penyakit dan abnormalitas organ tubuh. Pemeriksaan post-mortem pada hewan kurban sapi dan kambing dilakukan dengan inspeksi, palpasi dan pengirisan terhadap terhadap organ dan jaringan hewan kurban. Hasil pemeriksaan kesehatan ante-mortem terhadap 11 hewan kurban yang terdiri dari 3 ekor sapi dan 8 ekor kambing di musholla Al-Atqiyah Kota Mataram tidak ditemukan gejala hewan yang sakit. Hasil pemeriksaan post-mortem terkait organ hati, jantung, limfa, paru-paru, dan ginjal sebagai indikasi adanya penyakit dari 11 hewan kurban yang dipotong tidak ditemukan adanya perubahan organ dan tanda-tanda penyaki zoonosis, hanya ditemukan adanya cacing Fasciola sp, sehingga daging dan organ dalam hewan kurban diijinkan untuk didistribusikan untuk dikonsumsi.
Pelatihan Aplikasi Komputer Microsoft Word, Microsoft Excel, SPSS Bagi Siswa-Siswa SMA Kristen Tunas Bangsa Cakung
Authors: Wasito Budi , Brastoro  , Birowo Sigit
Published: December 2023

Perkembangan teknologi informasi kini semakin maju dengan adanya alat yang memudahkan manusia bekerja secara efektif dan efisien, yaitu media komputer. Adapun aplikasi yang begitu banyak diperlukan dan digunakan oleh sebagian besar masyarakat adalah aplikasi untuk perkantoran dalam hal ini adalah Microsoft Office dan SPSS. Ada kalanya seseorang ingin mengetahui sejauh mana tingkat kemampuan yang dimilikinya dalam penguasaan program tersebut sedangkan masih sedikitnya lembaga atau instansi terkait yang menyediakannya. Dengan adanya pelatihan diharapkan dapat dan mampu mengoptimalkan kemampuannnya serta  merasa diakui kemampuannya dalam mengolah Aplikasi Ms. Office dan Aplikasi SPSS dan dibantu dengan cara yang mudah untuk mendapatkannya, maka dengan media internet yang canggih dapat memungkinkan kita untuk melakukan latihan tes secara online dengan mudah tanpa harus melakukan kursus yang membutuhkan waktu yang  lama sehingga dengan waktu yang relatif sedikit kita dapat mengetahui tingkat kemampuan penguasaan program aplkasi  dalam hal ini Microsoft Office dan SPSS.
A training method for deep neural network inference accelerators with high tolerance for their hardware imperfection
Authors: Gao Shuchao , Ohsawa Takashi
Published: December 2023

We propose a novel training method named hardware-conscious software training (HCST) for deep neural network inference accelerators to recover the accuracy degradation due to their hardware imperfections. Existing approaches to the issue, such as the on-chip training and the in situ training, utilize the forward inference data that are obtained by the inference accelerators for the backpropagation. In the approaches, since the memory devices that are used for the weights and the biases are to be switched after each epoch, the total number of the switching in the training process grows too large to avoid the problems of endurance limitation, nonlinearity and asymmetry in the switching of the nonvolatile memories used for the weights and the biases. The proposed training method is totally conducted by software whose forward inference path and backpropagation reflect the hardware imperfections, overcoming all the above problems. The HCST reformulates the mathematical expressions in the forward propagation and the gradient calculation with the backpropagation so that it replicates the hardware structure under the influence of variations in the chip fabrication process. The effectiveness of this approach is validated through the MNIST dataset experiments to manifest its capability to restore the accuracies. A circuit design is also disclosed for measuring the offset voltages and the open loop gains of the operational amplifiers used in the accelerator, showing that the chip area overhead is minor.
First-principles study for orientation dependence of band alignments at the 4H-SiC/SiO2 interface
Authors: Matsuda Shun , Akiyama Toru , Hatakeyama Tetsuo , Shiraishi Kenji , Nakayama Takashi
Published: December 2023

The orientation dependence of band alignments and the formation of dipoles at the 4H-SiC/SiO2 interface are theoretically investigated on the basis of first-principles calculations. The calculations demonstrate that the offsets of valence and conduction bands depend on the surface orientation and chemical bonds at the 4H-SiC/SiO2 interface. When we exclude the interfaces with C–O bonds which result in CO desorption, the calculated conduction band offset (CBO) on the Si-face with Si-O bonds is larger than those on the C-face with C–Si bonds and m-face with both Si-O and C–Si bonds. Furthermore, it is found the atomic configurations at the 4H-SiC/SiO2 interface result in the formation of dipoles, whose magnitude is large for Si–O and C–O bonds. The formation of large dipoles significantly changes the band structure of 4H-SiC, resulting in large conduction bands offset. Therefore, the formation of a Si-O bond with large dipoles at the interface is of importance in order to obtain a large CBO. The calculated results give insights into improving the reliability of SiC MOSFETs.