bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and validation of search filters to find articles on palliative care in bibliographic databases
Authors: Rietjens Judith AC , Bramer Wichor M , Geijteman Eric CT , van der Heide Agnes , Oldenmenger Wendy H
Published: January 2019

Background:

Healthcare professionals and researchers in the field of palliative care often have difficulties finding relevant articles in online databases. Standardized search filters may help improve the efficiency and quality of such searches, but prior developed filters showed only moderate performance.

Aim:

To develop and validate a specific search filter and a sensitive search filter for the field of palliative care.

Design:

We used a novel, objective method for search filter development. First, we created a gold standard set. This set was split into three groups: term identification, filter development, and filter validation set. After creating the filters in PubMed, we translated the filters into search filters for Ovid MEDLINE, Embase, CINAHL, PsychINFO, and Cochrane Library. We calculated specificity, sensitivity and precision of both filters.

Results:

The specific filter had a specificity of 97.4%, a sensitivity of 93.7%, and a precision of 45%. The sensitive filter had a sensitivity of 99.6%, a specificity of 92.5%, and a precision of 5%.

Conclusion:

Our search filters can support literature searches in the field of palliative care. Our specific filter retrieves 93.7% of relevant articles, while 45% of the retrieved articles are relevant. This filter can be used to find answers to questions when time is limited. Our sensitive filter finds 99.6% of all relevant articles and may, for instance, help conducting systematic reviews. Both filters perform better than prior developed search filters in the field of palliative care.
From hoping to help: Identifying and responding to suicidality amongst victims of domestic abuse
Authors: Munro Vanessa E , Aitken Ruth
Published: January 2019

This article analyses findings from a large-scale study conducted in England and Wales into the prevalence of, and mediators and moderators of risk in relation to, suicidality amongst victims of domestic abuse. The authors tracked (disclosed) experiences of suicidal ideation or suicide within a sample of more than 3,500 domestically abused adults and explored factors that appeared to be correlated with a presence of suicidality amongst this constituency. This analysis was triangulated with a series of 20 semi-structured interviews which explored on-the-ground challenges in relation to the identification of, and support provision for, this vulnerable group, and which also included reflection on the difficulties experienced by staff as a consequence of the emotionally demanding nature of their interactions with such clients. Based on their findings, in this article, the authors underscore the need for more effective multi-agency cooperation, for greater priority to be given to self-harm and suicidality in risk-assessment processes, and for sustainable resourcing of domestic abuse service providers. In a context in which suicidality was correlated with experiences of isolation and hopelessness, they also emphasise the importance of appropriate and effective engagement by state agencies and those professionals tasked with intervening to help victims of domestic abuse.
“Would You Be My Friend?”: Friendship Selection and Contagion Processes of Early Adolescents Who Experience Victimization
Authors: Berger Christian , Gremmen Mariola Claudia , Palacios Diego , Franco Eduardo
Published: January 2019

Victimization in early adolescence can have severe negative consequences later in life. Friendships are especially important in this time period. The present study investigated friendship selection and influence (contagion) processes with regard to victimization, as well as prosocial and aggressive characteristics of victims’ friends. Using social network analyses (RSiena), we longitudinally analyzed data of five fourth-grade classrooms, including 185 students (56.8% girls; [Formula: see text] age at Time 1 = 10 years old). Results showed that early adolescents who experience peer victimization were not likely to select peers with similar levels of victimization as friends but selected prosocial peers as friends. Moreover, friends did not become more similar over time in their victimization levels. Prosocial students selected similar peers as friends. The discussion highlights the relevance of fostering positive peer relations for targeting victimization and discusses the defending role of friends in victimization situations.
Pathogenesis of Bohle Iridovirus (Genus Ranavirus) in Experimentally Infected Juvenile Eastern Water Dragons (Intellagama lesueurii lesueurii)
Authors: Maclaine Alicia , Forzán María J. , Mashkour Narges , Scott Jennifer , Ariel Ellen
Published: January 2019

Juvenile eastern water dragons ( Intellagama lesueurii lesueurii) are highly susceptible to infection with Bohle iridovirus (BIV), a species of ranavirus first isolated from ornate burrowing frogs in Townsville, Australia. To investigate the progression of BIV infection in eastern water dragons, 11 captive-bred juveniles were orally inoculated with a dose of 104.33 TCID50 and euthanized at 3, 6, 8, 10, 12, and 14 days postinfection (dpi). Viral DNA was detected via polymerase chain reaction (PCR) in the liver, kidney, and cloacal swabs at 3 dpi. Mild lymphocytic infiltration was observed in the submucosa and mucosa of the tongue and liver at 3 dpi. Immunohistochemistry (IHC) first identified viral antigen in foci of splenic necrosis and in hepatocytes with intracytoplasmic inclusion or rare single-cell necrosis at 6 dpi. By 14 dpi, positive IHC labeling was found in association with lesions in multiple tissues. Selected tissues from an individual euthanized at 14 dpi were probed using in situ hybridization (ISH). The ISH labeling matched the location and pattern detected by IHC. The progression of BIV infection in eastern water dragons, based on lesion severity and virus detection, appears to start in the spleen, followed by the liver, then other organs such as the kidney, pancreas, oral mucosa, and skin. The early detection of ranaviral DNA in cloacal swabs and liver and kidney tissue samples suggests these to be a reliable source of diagnostic samples in the early stage of disease before the appearance of clinical signs, as well as throughout the infection.
Oculodermal Melanocytosis: Nevus of Ota in a Dog
Authors: Giannikaki Stamatina , Sturgess Kit , Scurrell Emma , Cebrian Prado , Escanilla Natalia , Lowe Robert C.
Published: January 2019

This report describes the clinical presentation, diagnosis, and histopathologic features of oculodermal melanocytosis in a young dog. A 3-year-old male neutered Labrador Retriever presented with conjunctival and scleral hyperpigmentation of the right eye, with concurrent ipsilateral cutaneous hyperpigmentation involving the right side of the face. Initial skin and conjunctival biopsies revealed an accumulation of histologically benign melanocytes within the dermis and conjunctival stroma, respectively. Enucleation was elected 19 months later by the referring veterinarian due to the progression of ocular pigmentation with concurrent marked corneal lipidosis and the suspicion of a scleral mass. On gross and histopathologic examination of the globe, there was marked panuveal melanocytosis with extension into the sclera, bulbar conjunctiva, and connective tissue surrounding the optic nerve, as well as sharply demarcated ipsilateral hyperpigmentation of the facial skin. The findings are characteristic of oculodermal melanocytosis (nevus of Ota), a dermal melanocytic hamartoma presenting as cutaneous facial hyperpigmentation that corresponds to the distribution of the ophthalmic and maxillary branches of the trigeminal nerve, often with ipsilateral ocular involvement.
Expression and Roles of S100A4 in Anaplastic Cells of Canine Mammary Carcinomas
Authors: Yoshimura Hisashi , Otsuka Aya , Michishita Masaki , Yamamoto Masami , Ashizawa Minori , Zushi Manami , Moriya Maiko , Azakami Daigo , Ochiai Kazuhiko , Matsuda Yoko , Ishiwata Toshiyuki , Kamiya Shinji , Takahashi Kimimasa
Published: January 2019

S100A4 (metastasin), a member of the S100 protein family, was initially identified in metastatic cells and is well established as a marker of aggressive human cancer. However, expression and roles of S100A4 in canine mammary tumors have not been clarified. In this study, expression of S100A4 was examined immunohistochemically in normal, hyperplastic, and neoplastic mammary glands of dogs. In all normal and benign lesions, S100A4 was restricted to a few stromal fibroblasts and inflammatory cells. However, in 7 of 57 (12%) of the malignant tumors examined, cytoplasmic and nuclear expression of S100A4 was observed in epithelial tumor cells and stromal cells. Particularly, the frequency of S100A4-positive anaplastic carcinomas was high (4/8 cases, 50%). Next, we established a novel cell line, named NV-CML, from a S100A4-positive canine mammary carcinoma. The cultured NV-CML cells and the tumors that developed in the immunodeficient mice after subcutaneous injection of the cells maintained the immunophenotype of the original tumor, including S100A4 expression. Using this cell line, we examined the cellular functions of S100A4 using RNA interference. S100A4 expression level in NV-CML cells transfected with small interfering RNA (siRNA) targeting canine S100A4 (siS100A4) was reduced to about one-fifth of those with negative-control siRNA (siNeg). Cell proliferation in WST-8 assay and cell migration in Boyden chamber assay were significantly decreased in siS100A4-transfected cells compared with siNeg-transfected cells. These findings suggest that S100A4 may be related to progression of canine mammary carcinomas via its influence on cell growth and motility.
Fascioloides magna in Moose (Alces alces) From Elk Island National Park, Alberta
Authors: Shury Todd K. , Pybus Margo J. , Nation Nick , Cool Normand L. , Rettie W. James
Published: January 2019

Thirty-seven adult female moose ( Alces alces) from 2 distinct but adjacent populations in Elk Island National Park (EINP), Alberta, Canada (19 in north EINP and 18 in south EINP), were fitted with mortality-sensing VHF radio-collars, and radio signals were acquired daily to ascertain mortality status. At capture, serum, whole blood, and feces were collected; pregnancy was determined; teeth were aged by visual inspection; and a portion of liver was assessed by ultrasound examination. Postmortem examination was conducted on 20 suitable carcasses. Clinical pathological abnormalities, including eosinophilia, polycythemia, elevated levels of liver enzymes in serum, hemoglobin, hematocrit, and red blood cell distribution, and liver damage as seen in ultrasound images occurred only in moose from north EINP. Infected moose had 4.7 ± 4.8 Fascioloides magna flukes per liver (mean ± SD). The proportion of moose pregnant at capture was similar in both populations (74% in north EINP, 61% in south EINP). Proportional mortality was significantly higher in moose from the north (68%) than the south (32%). Fascioloides magna was associated as a cause of death in 7 of 14 (50%) moose in the north where cause of death was determined, while predation ( n = 1), acute toxemic syndrome ( n = 3), dystocia ( n = 1), and roadkill and undetermined causes ( n = 3) were additional causes of mortality. F. magna was associated with poor body condition and was a major cause of mortality in north EINP but not south EINP, despite very similar habitat and proximity, suggesting a significant role for these flukes in affecting health and viability of naturally infected moose populations.
Lesions and Distribution of Viral Antigen in the Brain of Hamsters Infected With Equine Herpesvirus (EHV)–9, EHV-1 Strain Ab4p, and Zebra-Borne EHV-1
Authors: El-Habashi Nagwan , El-Nahass EL-Shaymaa , Abd-Ellatieff Hoda , Saleh Asmaa , Abas Osama , Tsuchiya Yuya , Fukushi Hideto , Yanai Tokuma
Published: January 2019

Encephalitis in hamsters, which was induced by equine herpesvirus (EHV)–9, EHV-1 strain Ab4p, and zebra-borne EHV-1, was investigated and compared to assess viral kinetics and identify the progression and severity of neuropathological findings. Hamsters were inoculated with EHV-9, EHV-1 strain Ab4p, and zebra-borne EHV-1 via the nasal route and euthanized at 24, 48, 72, 96, 120, 144, and 168 hours postinoculation (HPI). The inoculated hamsters had mild to severe neurological signs at 60 to 72, 96, and 120 HPI, and the mortality rate was 75%, 0%, and 0% for animals inoculated with EHV-9, EHV-1 strain Ab4p, and zebra-borne EHV-1 viruses, respectively. Inoculated hamsters had varying degrees of rhinitis and lymphoplasmacytic meningoencephalitis, as well as differences in the severity and distribution of cerebral lesions. Furthermore, the cellular distribution of viral antigen depended on the inoculated virus. Neuronal necrosis was widely detected in animals inoculated with EHV-9, while marked perivascular cuffs of infiltrating inflammatory cells and gliosis were detected in animals inoculated with EHV-1 strain Ab4p and zebra-borne EHV-1. In the present study, 3 viruses belonging to the herpesvirus family induced encephalitis after initial propagation in the nasal cavity. These viruses might travel to the brain via the olfactory pathway and/or trigeminal nerve, showing different distributions and severities of neuropathological changes.
Emotions, power, and environmental conflict: Expanding the ‘emotional turn’ in political ecology
Authors: González-Hidalgo Marien , Zografos Christos
Published: January 2019

Building on the framework of emotional political ecology, we seek to expand ways of studying the relationships between emotion, power, and environmental conflict. Our review of work in feminist studies, human geography, social psychology, social movement theory, and social and cultural anthropology suggests the need for a theoretical framework that captures the psychological, more-than-human, collective, geographical, and personal-political dimensions that intersect subjectivities in environmental conflicts. We stress the need to explicitly consider ‘the political’ at stake when researching emotions in environmental conflicts, and develop a conceptual framework for facilitating nuanced conceptualisations and analyses of subjects and power in environmental conflicts.
A classic that wasn’t: Statistical Geography and paths only later taken
Authors: Johnston Ron , Jones Kelvyn
Published: January 2019

Science is a cumulative activity, a body of knowledge sedimented in its publications, which form the foundation for further activity. Some items attract more attention than others; some are largely ignored. This paper looks at a largely overlooked book – Statistical Geography – published by three US sociologists at a time when geographers were launching their ‘quantitative revolution’. There was little literature within the discipline on which that revolution could be based, and a book with that title could have been seminal. But it was not, and as a consequence – as illustrated with three examples – major issues in spatial analysis were not addressed in the revolution’s early years. The paper explores why.
Assessment of a numerical design tool for pitching airfoils
Authors: Wellenberg Sören , Marnett Markus , Roidl Benedikt , Kirkendall Davis , Thönnißen Frederik , Schröder Wolfgang
Published: January 2019

The aim of this study was to assess the applicability of a numerical design tool for pitching airfoils; by evaluating their aerodynamic performance comparing experimental and numerical data at different levels of complexity. Experimental findings of non-harmonically pitching airfoil configurations in a water tunnel at medium Reynolds numbers are compared to solutions of a modified double-wake vortex-panel method with boundary-layer formulation and unsteady Reynolds-averaged Navier–Stokes simulations. For steady-state airfoil configurations at high angle of attack, large eddy simulation data are also considered. Rigorous analysis of the sources of error and uncertainty in numerical methods and measurements proves that from an engineering point of view, a low-cost double-wake model is well suited for the design process of, for example, wind-turbine blades. That is, the overall first-order error and uncertainty of the double-wake panel method with a strong viscous-inviscid interaction model are in a reasonable range against the measurements and the much more expensive numerical methods. Thus, the low computational costs plus the accuracy make the unsteady panel-boundary-layer method a useful and reliable tool to analyze the aerodynamics of pitching airfoils in the design process.
Food Aid for Nutrition: Narrative Review of Major Research Topics Presented at a Scientific Symposium Held October 21, 2017, at the 21st International Congress of Nutrition in Buenos Aires, Argentina
Authors: Caiafa Kristine , Dewey Kathryn G. , Michaelsen Kim F. , de Pee Saskia , Collins Steve , Rogers Beatrice Lorge , El-Kour Tatyana , Walton Shelley , Webb Patrick
Published: January 2019

Background:

Food aid is a valuable tool for meeting global nutrition goals, particularly for vulnerable populations of children and reproductive-aged women. On October 21, 2017, the Food Aid Quality Review Project hosted a scientific symposium at the 21st International Congress on Nutrition in Buenos Aires, Argentina, to take stock of what the global community has learned about selected topics in the research literature on food aid used to address malnutrition.

Objective:

This article presents the discussion that took place during the symposium, which was guided by presentations by 6 experts from the field of nutrition, food aid, and humanitarian response.

Conclusion:

The recent upsurge in research on food aid has advanced the collective knowledge of what food aid products and programs work for addressing nutrition, but there is much more to learn. Presentations in this symposium called for further inquiry on (1) different and novel food aid formulations, (2) the cost-effectiveness of products and programs, and (3) market-based approaches to food assistance. Continuing to expand the evidence base on these topics is critical to improving global nutrition programs.
Life cycle assessment for solid waste management in Lebanon: Economic implications of carbon credit
Authors: Maalouf Amani , El-Fadel Mutasem
Published: January 2019

Solid waste management has witnessed much progress in recent years with considerable efforts targeting the reduction of associated impacts and carbon emissions. Such efforts remain relatively limited in developing economies due to inefficient management practices. In this study, a life cycle assessment (LCA) approach is adopted to identify integrated systems with minimal impacts and reduced emissions in a developing context coupled with an economic valuation and sensitivity analysis to assess the effect of varying influencing parameters individually. The results showed that the highest impact arises from landfilling with minimal material recovery for recycling and composting, while incineration coupled with energy recovery contributed to the least equivalent emissions (–111% with respect to baseline scenario) at a varying cost of −70% to +93% depending on the selected technology and the value of carbon credit. Optimizing material recycling, composting and landfilling with energy recovery contributed to 98% savings in emissions (with respect to baseline scenario) and remained economically attractive irrespective of the carbon credit exchange rate of 0.5–50 US$/MTCO2E. The sensitivity analysis showed that an improvement in landfill gas collection efficiency (up to 60%) can contribute to major savings in emissions (58%). The application of the LCA-based approach supports the development of integrated viable plans while quantifying advantages and disadvantages towards decision-making and policy-planning.
Design opportunities for organic waste recycling in urban restaurants
Authors: Vinck Kathleen , Scheelen Linda , Du Bois Els
Published: January 2019

This research project focuses on the problem of organic (or food waste) waste recycling in Flanders, Belgium. Here, the total amount of organic waste produced annually by restaurants is estimated at 166,000 tonnes. Despite being in the evolution towards a circular economy, more than 61% of the restaurants do not collect organic waste separately from residual waste. Within the research, this problem was explored from a human-centred perspective by analysing existing food-waste collection and processing equipment, and by observing the kitchen workflow and interior design of different urban located restaurants. The aim of the research was to identify design opportunities to integrate and optimize the collecting and recycling of food waste in restaurants. In sum, it was possible to distinguish different elements, variables and constraints across the various restaurants related to the disposal and handling of food waste in the kitchen and in the clearing area during the shift. The paper concludes with design requirements for the optimization of food-waste recycling systems, which are related to the cost of the system, the effort that is needed, the lack of space, potential bad odour, hygiene matters, integration in the workflow, organization of the workspace and use of additional resources and energy.
Do socioeconomic factors influence households’ solid waste disposal systems? Evidence from Ghana
Authors: Adzawla William , Tahidu Adam , Mustapha Salisu , Azumah Shaibu B.
Published: January 2019

Solid waste management remains a major challenge in Ghana, especially in the peri-urban and urban areas. The implications from this bottleneck are widely acknowledged. Nonetheless, fundamental issues such as the factors that drive households into the adoption of a particular solid waste disposal system have not been explored. This study applied a multinomial logit approach using 16,767 households in the Ghana Living Standard Survey round six data to examine whether or not socioeconomic factors influence households’ decision to adopt a particular solid waste disposal system. The results established that a number of the hypothesised socioeconomic factors drive households into the use of a particular solid waste disposal system. For instance, education of households on solid waste management is important to increase households’ decision into collecting wastes other than open dumping or burning. The characteristics of houses and the location of households also influence waste disposal systems in Ghana. We conclude that solid waste disposal at unapproved places was largely influenced by socioeconomic characteristics other than income or welfare of households. We recommend continuous advocacy programmes on improved solid waste management systems, led by the various decentralised governance structures such as the District Assemblies, to curb the menace.
Benchmarking performance of solid waste management and recycling systems in East Africa: Comparing Kigali Rwanda with other major cities
Authors: Kabera Telesphore , Wilson David C , Nishimwe Honorine
Published: January 2019

This paper aims to benchmark performance of combined solid waste management (SWM) and recycling systems in major cities of East Africa. The Wasteaware indicators are used to present a detailed systems analysis for Kigali in Rwanda, including a mass flow diagram; comparative data are taken from the Wasteaware database for Dar es Salaam, Tanzania, Kampala, Uganda, Nairobi, Kenya, and also for neighboring Maputo, Mozambique. The stand-out result is the relatively high collection coverage achieved, in Maputo with extensive international technical assistance, and in Kigali using its own local resources. In both cases, governance factors are key. Kigali uses a public–private partnership, with exclusive franchises in 35 sectors being tendered every three years; households pay an affordable fee depending on their ability to pay (the service is free to the poorest category); and 95% fee collection rates are achieved, partly through co-collection with charges for local security patrols, which is a service people value highly given the recent history of the country. Another key priority to improve SWM across East Africa is to eliminate open dumping – only Kampala currently has an engineered disposal site. Recycling rates also need to be increased – only Nairobi currently has a good baseline to build on (30%). Common weaknesses include a lack of segregation at source, of institutional capacity, and of available and reliable waste data.
Thermal treatment of carbon fibre reinforced polymers (Part 1: Recycling)
Authors: Limburg Marco , Stockschläder Jan , Quicker Peter
Published: January 2019

The increasing use of carbon fibre reinforced polymers requires suitable disposing and recycling options, the latter being especially attractive due to the high production cost of the material. Reclaiming the fibres from their polymer matrix however is not without challenges. Pyrolysis leads to a decay of the polymer matrix but may also leave solid carbon residues on the fibre. These residues prevent fibre sizing and thereby reuse in new materials. In state of the art, these residues are removed via thermal treatment in oxygen containing atmospheres. This however may damage the fibre’s tensile strength. Within the scope of this work, carbon dioxide and water vapour were used to remove the carbon residues. This aims to eliminate or at least minimize fibre damage. Improved quality of reclaimed fibres can make fibre reuse more desirable by enabling the production of high-quality recycling products. Still, even under ideal recycling conditions the fibres will shorten with every new life-cycle due to production-based blending. Fibre disposal pathways will therefore always also be necessary. The problems of thermal fibre disintegration are summarized in the second part of this article (Part 2: Energy recovery).
Prevention of Child Sexual Exploitation: Insights From Adult Survivors
Authors: Hurst Tamara E.
Published: January 2019

This qualitative retrospective study explores the prevention of the commercial sexual exploitation of children (CSEC) from the perspectives of adult survivors. These participants represent a subsample ( n = 17) of a larger sample of adult female survivors ( n = 40) who took part in a research study concerning the influence of childhood emotional maltreatment on the vulnerability of CSEC. Participants learned of the study through CSEC-specific agencies and survivor listservs. All are United States’ citizens over the age of 18 years who were sexually exploited during their youth between the ages of 1 year and 17 years while residing in the United States. Six themes with relevance to vulnerability to recruitment and barriers to prevention emerged after analysis. These themes include difficulty trusting medical and mental health professionals; difficulty trusting law enforcement; protection of family members; self-destructive behaviors; a need for CSEC awareness in educational settings; and a need for CSEC awareness among at-risk youth. Extant literature previously identifies similar themes as areas of vulnerability to recruitment, however, these findings are specifically related to prevention programs. Implications for developing or improving prevention programs are discussed.
The role of climate, marine influence and sedimentation rates in late-Holocene estuarine evolution (SW Portugal)
Authors: Costa Ana Maria , Freitas Maria da Conceição , Leira Manel , Costas Susana , Costa Pedro JM , Andrade César , Bao Roberto , Duarte João , Rodrigues Aurora , Cachão Mário , Araújo Ana Cristina , Diniz Mariana , Arias Pablo
Published: January 2019

Estuaries are sensitive to changes in global to regional sea level, to climate-driven variation in rainfall and to fluvial discharge. In this study, we use source and environmentally sensitive proxies together with radiocarbon dating to examine a 7-m-thick sedimentary record from the Sado estuary accumulated throughout the last 3.6 kyr. The lithofacies, geochemistry and diatom assemblages in the sediments accumulated between 3570 and 3240 cal. BP indicate a mixture between terrestrial and marine sources. The relative contribution of each source varied through time as sedimentation progressed in a low intertidal to high subtidal and low-energy accreting tidal flat. The sedimentation proceeded under a general pattern of drier and higher aridity conditions, punctuated by century-long changes of the rainfall regime that mirror an increase in storminess that affected SW Portugal and Europe. The sediment sequence contains evidence of two periods characterized by downstream displacement of the estuarine/freshwater transitional boundary, dated to 3570–3400 cal. BP and 3300–3240 cal. BP. These are intercalated by one episode where marine influence shifted upstream. All sedimentation episodes developed under high terrestrial sediment delivery to this transitional region, leading to exceptionally high sedimentation rates, independently of the relative expression of terrestrial/marine influences in sediment facies. Our data show that these disturbances are mainly climate-driven and related to variations in rainfall and only secondarily with regional sea-level oscillations. From 3240 cal. BP onwards, an abrupt change in sediment facies is noted, in which the silting estuarine bottom reaches mean sea level and continued accreting until present under prevailing freshwater conditions, the tidal flat changing to an alluvial plain. The environmental modification is accompanied by a pronounced change in sedimentation rate that decreased by two orders of magnitude, reflecting the loss of accommodation space rather than the influence of climate or regional sea-level drivers.
Are Prominent Equity Market Anomalies in India Fading Away?
Authors: Sharma Gagan , Subramaniam Srividya , Sehgal Sanjay
Published: January 2019

In this study, we revisit prominent equity market anomalies documented for India, namely size, value, volume and momentum. Using data for NSE 500 companies, we test for the persistence of these anomalies for a recent period from July 2005 to June 2016 employing one-factor capital asset pricing model (CAPM) and three-factor Fama–French model as asset pricing benchmarks. We test for the robustness of these anomalies by (a) forming both quintile and decile portfolios and (b) forming univariate and variety of bivariate-sorted portfolios. Corner portfolios based on deciles provide greater return differentials compared to quintile portfolios. Bivariate-sorted portfolios do not seem to outperform univariate-sorted portfolios. The value and momentum anomalies are explained by risk models which is contrary to prior evidence. Size and volume anomalies continue to provide significant returns but seem to have faded substantially over time when compared with the past results. The findings about weakening prominent Indian equity market anomalies shall pose a challenge for portfolio managers who may have to look for other sources of extra-normal profits. Indian market also seems to be informationally more efficient which is in line with recent financial market reforms and growing emphasis on financial inclusion and corporate governance.
The evolving notion of mutual recognition in the CJEU’s case law on detention
Authors: Caeiro Pedro , Fidalgo Sónia , Rodrigues João Prata
Published: January 2019

This article analyses the case law of the Court of Justice of the European Union (CJEU) on detention and the possible evolution of the understanding of mutual recognition stemming therefrom. In the Lanigan, JZ, and Ognyanov decisions, the CJEU assimilated mutual recognition with the effectiveness of cooperation, which should be understood as maximum compliance with the issuing state’s interests. Arguably, this approach is detrimental to other important values, such as, for example, the rights arising from excessively long detention and a rational and meaningful approach to the enforcement of imprisonment. On the other hand, the Aranyosi and Căldăraru judgment has detached mutual recognition from the exclusive protection of the issuing state and has turned it into a neutral governance principle. If mutual trust is not a given and can be assessed on a case-by-case basis through common objective parameters, the decisions deserving recognition may be uttered either by the issuing or the executing authority.
The Progression and Future of Nursing in Singapore: A Descriptive Qualitative Study
Authors: Shorey Shefaly , Goh Mien Li , Ang Shin Yuh , Ang Lina , Devi M Kamala , Ang Emily
Published: January 2019

Introduction: Nursing professionalism and nursing identity are important for retention of nurses. Despite of much attention on nurses in Singapore, there is still a shortage of nurses. This study aims to understand the perceptions of the progression and future of the nursing profession in Singapore. Methodology: A descriptive qualitative study design was used. The participants were 20 nurse educators, clinical nurses, and student nurses. Data were collected through focus group and online interviews and analyzed thematically. Results: Nurses felt a need to bridge the theory–practice gap and various factors to the underlying cause of the shortage of nurses were highlighted. Nurses shared their desires to see greater autonomy among nurses and a greater focus on community nursing in the future. Discussion: Collaboration between nurse academics and clinical nurses may bridge the theory–practice gap. To reduce the issue of the shortage of nurses, efforts to promote nursing professionalism are required.
Cultural Competences Gained Through an Education Program as Ethnic Patient Coordinator: A Qualitative Study
Authors: Nielsen Dorthe S. , Korsholm Karen M. , Mottelson Ida , Sodemann Morten
Published: January 2019

Introduction: Studies have shown that health care professionals lack cultural knowledge and cultural competences in the care of patients with a minority background. The aim of this study was to explore whether a cultural teaching program, the so-called ethnic patient coordinator program, had an impact on health professionals’ self-perceived clinical competences in the encounter with the minority patient. Methodology: The study was designed as a qualitative study using participant observation and semistructured interviews with a practice-led research approach. In total, 30 health professionals participated in the program. Results/Discussion: The coordinators described that they had learned to focus systematically on reducing language barriers and to overcome prejudices. Their new competences not only had a direct influence on patient-related practical skills but also affected the practice culture and their colleagues’ approach to vulnerable patients with a minority background. Conclusion/Implication: The presence of an ethnic patient coordinator team may give rise to a more migrant-friendly and culturally competent hospital.
Weakest Link Goal Orientations and Team Expertise: Implications for Team Performance
Authors: Valcea Sorin , Hamdani Maria , Bradley Bret
Published: January 2019

Using prior theory and research, we argue that a team member with a low learning goal or a high avoid orientation is detrimental for the expertise–performance relationship in team tasks. Results from a study of 82 teams showed that, after controlling for goal orientation team composition, expertise improved team performance only when teams did not have a weak link team member. In contrast, when teams had this weak link teammate, expertise did not improve performance, and in some cases damaged it. Implications for theory and practice are discussed.
Ginseng: A Qualitative Review of Benefits for Palliative Clinicians
Authors: Davis Mellar P. , Behm Bertrand
Published: January 2019

Ginseng has been used for centuries to treat various diseases and has been commercially developed and cultivated in the past 300 years. Ginseng products may be fresh, dried (white), or dried and steamed (red). Extracts may be made using water or alcohol. There are over 50 different ginsenosides identified by chromatography. We did an informal systematic qualitative review that centered on fatigue, cancer, dementia, respiratory diseases, and heart failure, and we review 113 studies in 6 tables. There are multiple potential benefits to ginseng in cancer. Ginseng, in certain circumstances, has been shown to improve dementia, chronic obstructive pulmonary disease, and heart failure through randomized trials. Most trials had biases or unknown biases and so most evidence is of low quality. We review the gaps in the evidence and make some recommendations regarding future studies.
Challenges and Conundrums: Teaching and Learning From a U.K. Dean’s Perspective
Authors: Cassell Catherine
Published: January 2019

In this article, I present some of the teaching and learning challenges faced from the perspective of a U.K. business school dean. There are many challenges that I could have chosen, but my focus is on the unpredictable external environment, the conundrum of teaching evaluation, developing teaching staff, and the curriculum issues we face.
Selecting Evidence-Based Practices: What Works for Me
Authors: Leko Melinda M. , Roberts Carly , Peyton David , Pua Daisy
Published: January 2019

As the special education research community continues to identify new evidence-based practices (EBP), educators will need to make choices regarding which EBPs to implement. This article provides educators with practical guidelines for selecting EBPs that will improve outcomes for students with learning disabilities (LD), emotional and behavior disorders (EBD), and autism spectrum disorder (ASD). Among the factors for EBP consideration discussed are strength of evidence, cost, complexity and transferability, and contextual fit. By taking these factors (and others) into consideration, educators can make more informed decisions from the outset about which EBPs will work in their particular contexts, meet the specific needs of their students, and lead to long-term sustainability.
Cultural Relevance in Special Education: Current Status and Future Directions
Authors: Brown Monica R. , Dennis June P. , Matute-Chavarria Monique
Published: January 2019

Increasingly, educators have been charged with delivering academic and other instruction to groups of students who are culturally unlike themselves. What teachers know regarding the attitudes toward cultural diversity can be a powerful determinant of the academic, social, and behavioral opportunities and outcomes for students from culturally and linguistically diverse backgrounds in special education. Teachers are encouraged to integrate culturally responsive (CR) practices across the special education experience to better address the needs of these students. Typically, when included, it is in the areas of school discipline (behavior), transition, and family involvement. In this article, the authors discuss (a) the minoritization of students from culturally and linguistically diverse backgrounds, (b) the effects of forced special education (e.g., overrepresentation and disproportionality), and (c) current CR practices in special education (e.g., working with families, classroom and behavior management, and transition services). Suggestions for creating culturally sustaining and inclusive environments in special education are recommended.
Pharmacy-Led β-Lactam Allergy Interview (BLAI) Reduces Duration of Fluoroquinolones Within a Community Hospital
Authors: Covington Elizabeth W. , Baldwin Beth Jobson , Warren Emily
Published: January 2019

Background: Patients with reported β-lactam allergies often receive broad-spectrum antimicrobials and have been shown to experience a variety of negative health consequences, such as increased mortality, costs, readmission, and adverse reactions. Current literature focuses on β-lactam allergy skin testing but lacks evidence on β-lactam allergy interviews (BLAI) when skin testing is unavailable. Objective: This study aimed to test the impact of a pharmacy-led BLAI on duration of fluoroquinolones at a community hospital. Methods: A quasi-experimental design with a prospective cohort design and historical control group was used to assess patients with reported penicillin (PCN) allergies in a community hospital. The primary outcome was duration of fluoroquinolones before and after implementation of BLAI. Secondary outcomes included length of stay (LOS), percentage of patients switched to a β-lactam antibiotic, percentage of antimicrobial stewardship recommendations made/accepted, and discrepancies between allergy in medical record and interview-reported allergy. Nonparametric continuous data and medians were evaluated by Mann-Whitney U. Results: A total of 80 patients were included in the study (43 in the control group and 37 in the prospective group). Fluoroquinolone duration was reduced after the implementation of BLAI (3.7 vs 2.7 days, P = 0.027). In all, 49% of patients in the prospective group were switched to a β-lactam antibiotic after BLAI, with no allergic reactions, adverse effects, or impact on LOS. Conclusion and Relevance: BLAI resulted in a significant reduction in fluoroquinolone duration in patients with PCN allergies and may represent a safe and effective option for institutions lacking skin-testing capabilities.
Correlation of Soft Tissue Swelling and Timing to Surgery With Acute Wound Complications for Operatively Treated Ankle and Other Lower Extremity Fractures
Authors: Riedel Matthew D. , Parker Amber , Zheng Mingxin , Briceno Jorge , Staffa Steven J. , Miller Christopher P. , Kaiser Philip B. , Wu Jim S. , Zurakowski David , Kwon John Y.
Published: January 2019

Background:

Considerable debate exists regarding how soft-tissue edema should influence timing of surgery for ankle and other lower extremity fractures. Assessment of swelling is subjective, and timing varies among surgeons. However, timing of surgery is one of the few modifiable factors in fracture care. Ultrasonography can objectively measure swelling and help determine optimal timing. The purposes of this study were to determine whether objective measures of swelling, timing to surgery, and patient-specific risk factors correlated with wound complications and to try to create a prediction model for postoperative wound complications based on identified modifiable and nonmodifiable risk factors.

Methods:

Patients with closed ankle and other lower extremity fractures requiring surgery with an uninjured, contralateral extremity were included. Demographic information and sonographic measurements on both lower extremities were obtained pre-operatively. Subjects were followed for 3 months and wound complications were documented. A predictive algorithm of independent risk factors was constructed, determining wound complication risk. Given that patients with ankle fractures made up the majority of the study cohort (75/93 or 80%), a separate statistical analysis was performed on this group. A total of 93 subjects completed the study, with 75/93 sustaining ankle fractures.

Results:

Overall wound complication rate was 18.3%. Timing to surgery showed no correlation with wound complications. A heel-pad edema index >1.4 was independently associated with wound complications. Subgroup analysis of ankle fractures demonstrated a 3.4× increase in wound complications with a heel-pad edema index >1.4. Tobacco history and BMI >25 were independent predictors of wound complications. An algorithm was established based on heel-pad edema index, BMI >25, and tobacco history. Patients with none of the 3 factors had a 3% probability of a wound complication. Patients with 1/3, 2/3 and 3/3 factors had a 12-36%, 60-86% and 96% probability of a wound complication, respectively.

Conclusions:

Timing to surgery had no correlation with wound complications. Heel-pad edema index >1.4, BMI >25, and tobacco-use correlated with wound complications. When separately analyzing the cohort that sustained ankle fractures, the heel-pad edema index of >1.4 was still demonstrated to be predictive of wound complications corresponding to a 3.4× increase in wound complication rates (11.1% vs 37.5%). Risk of wound complications significantly increased with each factor. In patients with increased BMI and/or tobacco use, resolution of heel edema may significantly reduce wound complications in lower extremity trauma.

Level of Evidence:

Level II, prognostic, prospective cohort study.
Thromboprophylaxis for Hip Revision Arthroplasty: Can We Use the Recommendations for Primary Hip Surgery? A Cohort Study
Authors: Bautista Maria , Muskus Meilyn , Tafur Daniela , Bonilla Guillermo , Llinás Adolfo , Monsalvo Daniel
Published: January 2019

The risk of thromboembolic events after hip revision arthroplasty might be higher than in primary hip arthroplasty. However, evidence regarding the use of thromboprophylaxis in revisions is scarce. The purpose of this study is to determine whether thromboprophylaxis recommendations for primary arthroplasty produce similar results in hip revision arthroplasty. This comparative cohort study retrospectively analyzed consecutive patients undergoing primary hip arthroplasty and hip revision surgery between March 2004 and December 2015, who received thromboprophylaxis according to local clinical practice guidelines for primary hip arthroplasty. The prevalence of deep vein thrombosis and pulmonary embolism and the presence of major bleeding events were assessed during hospitalization and at 3 months after discharge and compared between groups. The overall prevalence of thromboembolic events in the hip revision surgery cohort and in the primary hip cohort was 1.62% and 1.35%, respectively ( P = .801). The 38.4% of hip revision patients and 20.3% of primary hip patients presented major bleeding events. Thromboembolic disease outcomes with the use of a standardized thromboprophylaxis regimen were similar in both cohorts, regardless of the high variability of hip revision surgery and the increased risk of complications. Implementation of this regimen is recommended in patients requiring joint replacement revision surgery.
Dynamic Analysis of Perioperative Hidden Blood Loss in Intertrochanteric Fractures
Authors: Tian Shuwei , Li Hui , Liu Meiyu , Zhang Yanlong , Peng Aqin
Published: January 2019

To analyze the dynamic variation in perioperative hidden blood loss in patients with intertrochanteric fracture. From January to December 2017, 79 patients with intertrochanteric fracture were treated with proximal femoral nail antirotation. Serial complete blood count assays were performed consecutively in the 3 days after admission, on the day of surgery, and 7 days postoperatively. Blood loss during surgery, postoperative drainage, and perioperative blood transfusion volumes were recorded. Dynamic changes in hemoglobin (Hb) prior to surgery were recorded and compared between males and females. Patients were divided into the no blood transfusion group, the 400-mL blood transfusion group, and the 800-mL blood transfusion group depending on the volume of perioperative blood transfusion. Total and hidden blood loss were separately calculated according to the Gross equation. Lowest mean Hb values occurred on day 2 after admission among men (104.8 g/L) and on day 3 after admission among women (98.6 g/L). The average Hb decrease was 11.4 g/L, 11.8 g/L, and 8.9 g/L in the no, 400-mL, and 800-mL blood transfusion groups, respectively. The lowest Hb value occurred on postoperative day 2. Hemoglobin increased on postoperative day 3 and stabilized by day 6. In the no blood transfusion group, the average total blood loss was 406.0 ± 255.6 mL, 628.3 ± 267.2 mL, and 759.7 ± 322.1 mL in the no blood transfusion, 400-mL blood transfusion, and 800-mL blood transfusion groups, respectively, and hidden blood loss was 326.0 ± 246.6 mL, 512.1 ± 247.3 mL, and 596.1 ± 306.9 mL, respectively. Perioperative hidden blood loss occurred prior to surgery for intertrochanteric fracture and ended on postoperative day 2.