bluuebunny/crossref_metadata_2025 huggingface dataset:
Reformasi Hukum Di Bidang Informasi Dan Transaksi Elektronik
Authors: Tarigan Sion , Maria Trianggraini Anna
Published: November 2023

Legal reform or renewal is an attempt to replace the existing legal rules in society in accordance with social, political developments and aspirations regarding the legal order aspired to by the community, one of which is renewal in the field of Information and Electronic Transactions, namely the ITE Law Number 11 of 2008 which an amendment has been made, namely Law No. 19 of 2016 concerning Amendments to Law No. 11 of 2008 concerning Information and Electronic Transactions, where the changes are intended to anticipate problems regarding ITE, and make it easier for law enforcement officials to take action against perpetrators, this research uses normative legal research on written regulations, so this research refers to literature because it requires data from literature, and in this legal research the data used, namely secondary data on the implementation of the ITE Law from 2008 to 2016, has many problems, such as provisions prohibiting the spread of illegal content often intersect with the protection of freedom of expression as a right protected and guaranteed by the constitution, more The ITE Law also presents a space for uncertainty in law enforcement, several criminal provisions in the ITE Law are duplicative and give the impression of overlapping with the provisions in the Criminal Code (KUHP), and are broadly formulated but have multiple interpretations. unclear, and contrary to the principle that criminal law must be clear or commonly called (lex certa) and strictly formulated (lex stricta). Reforms in the field of Information and Electronic Transactions have not shown significant changes and impacts on society, because they do not touch on the main issues in the 2008 ITE Law, issues related to the provisions and implementation of the ITE Law are still far from ideal, therefore it can be concluded that the possibility of updating the ITE Law Number 19 of 2016 is very wide open.
Pengaruh Work-Life Balance Dan Iklim Organisasi Terhadap Kepuasan Kerja Pada Tenaga Kependidikan Universitas Airlangga
Authors: Sabila Rosida Salwa , Chusairi Achmad
Published: November 2023

This study aims to determine the effect of work-life balance and organizational climate on job satisfaction in airlangga university educational staff. The hypotheses in this study are (1) work-life balance and organizational climate simultaneously affect job satisfaction: (2) work-life balance affect job satisfaction; and (3) organizational climate affects job satisfaction in airlangga university educational staff. The method in this study use quantitative research methods. The subjects in this study were 250 education staff working at airlangga university. The measurement tools used Work-life Balance (WLB), Organizational Climate Measure (OCM), Facet Satisfaction Scale (FSS). Data analysis used multiple liniear regression tests with IBM SPSS Statistic 27 for MAC. The results of data analysis show that work-life balance and organizational climate silmutaneously have a significant effect on job satisfaction of 0,000. Work-life balance shows a positive and significant influence on job satisfaction of 0,000, meaning that the higher the work-life balance, the higher the level of job satisfaction. Organizational climate shows a postifive and significant influence on job satisfaction of 0,000, meaning that the higher the organizational climate, the higher the level of job satisfaction.
Rancangan Sistem Informasi Penilaian Kinerja Karyawan Berbasis Proses Bisnis
Authors: Aulianisa Ridha , Yunani Akhmad
Published: November 2023

Employee performance appraisal is one that must be considered by a company in order to support employee performance evaluation and business processes that occur within the company. The process of identifying and evaluating the level of HR excellence can be obtained through a performance appraisal process. One of them is in a company engaged in the financial planning service industry, PT. My finances, which are still guided by manual Self Appraisal assessment for complete the performance appraisal process. This is the background of the author so that a business process-based employee performance appraisal design is made to make performance appraisals more effective and efficient. This research is a descriptive qualitative research that provides an overview of the company's internal conditions and describes the design of an employee performance appraisal system in accordance with the current performance appraisal process. The data validity technique used is triangulation technique to test credibility. In designing a business process-based performance appraisal system, there are three main processes, namely the input stage, the process stage and the output stage. The result of this research is the design of an employee performance appraisal system based on a business process that is objective, effective, efficient and avoids repetition of work. So that the HRD team can focus on maximizing the design of training programs for the development of my Financial HR in order to advance and support the company's growth.
Hubungan Ketergantungan Emosi Dan Kesepian Pada Emerging Adulthood Yang Menjalani Pacaran Jarak Jauh
Authors: Fredella Denisa , Diah Sosialita Tiara
Published: November 2023

Emerging adulthood those who are dating long distance feel insecure in their relationship and result in decreased emotional closeness which impacts on the level of loneliness. This study aims to determine the relationship between emotional dependency and loneliness in emerging adulthood who are in a long-distance relationship. Emotional dependence is a persistent pattern of unmet emotional needs that are attempted to be satisfied in a way that is not adaptive to others. Loneliness occurs when emotional and social needs are not met. This study uses a quantitative approach to the survey method. Participants in this study consisted of 156 emerging adults aged 18-25 years who underwent long-distance courtship. The measuring instrument used was The University of California, Los Angeles Loneliness Scale Version 3 (UCLA Version 3) and Partner's Emotional Dependency Questionnaire. which has been adapted into Indonesian. Data analysis used the Pearson's product moment correlation test with the help of SPSS 27 for Mac. The results of the research data analysis showed that the correlation coefficient between emotional dependence and loneliness in emerging adulthood who underwent long-distance courtship was 0.226, with a significance level of 0.004 (p>0.05). These results indicate that there is a positive and significant relationship, which means that the higher the emotional dependency, the higher the loneliness of emerging adults who undergo long-distance courtship.
Pengaruh Daya Tarik Wisata Terhadap Minat Berkunjung Wisatawan Di Kawasan Pecinan Glodok Jakarta Barat Sebagai Wisata Sejarah Dan Budaya
Authors: Alfandy Meidy , Rizki Krisnadi Antonius
Published: November 2023

Tourism is the second largest and most powerful sector in a world economic development. Indonesia is one of the developing countries in the tourism industry and has various natural and cultural beauties. Indonesia has many choices of tourist destinations, one of which is the Glodok Chinatown. The Glodok Chinatown area was once an isolation area for the Chinese ethnic community and at the same time became an economic center which has now become a tourist area with historical & cultural tourism potential. The purpose of this study was to find out whether there is an influence of tourist attraction in the Glodok Chinatown area on the interest of visiting tourists as historical & cultural tourism. This study used a total sample of 100 respondents. This study uses an instrument test consisting of validity and reliability tests. Then there is a classic assumption test which consists of a normality test and a heteroscedasticity test. Then there is a simple linear regression test and a hypothesis test which consists of a T test and the coefficient of determination. The results of the study show that tourist attraction has an influence on tourists' interest in visiting as historical & cultural tourism in the Glodok Chinatown area.
he ambiguous nature of hope : How a discourse of hope shapes the communicative conditions for exploring challenges in the circular economy transition
Authors: Åhlvik Therese
Published: November 2023

There is a widespread notion in society that communication about sustainability must be characterised by hope in order to advance the sustainability transition. It is also acknowledged that sustainability issues are complex, contested and involve large-scale collaboration between actors across different sectors with often diverse and conflictual interests and goals. The transition presupposes democratic processes where this complexity is fully appreciated. This requires communicative conditions that allow different interests and perspectives to be explored and disagreement to be expressed. In this dissertation, I investigate the communicative consequences of a discursive norm that favours expressions of hope in meetings about the circular economy, a context where the hope norm is prominent. The circular economy is considered to provide a “win-win” solution to the conflict between economic growth and the environment. However, the transition to a circular economy requires that the challenges inherent in navigating conceptual ambiguity, establishing large-scale collaboration and addressing political obstacles are explored. Using methods of conversation and discourse analysis, I investigate how a hope discourse is expressed in circular economy meetings and how it shapes the communicative conditions for meeting participants to explore challenges, and whether disagreements and a diversity of perspectives are expressed. I identify discursive repertoires that construct a collective of actors that are “stronger together” and create a driving force to bring about “real” change. Exploring these repertoires in more detail, I demonstrate that hope discourse discursively closes down the joint exploration of ambiguities, challenges and disagreements. Furthermore, hope discourse obscures talk about accountability, responsibility and agency. This results in a vague and shallow exploration of problems and challenges. I therefore conclude that the dominant hope discourse prevents actors from developing a richer understanding of the complexity of the sustainability transition.
REFORESTATION POTENTIAL OF TUGAI FORESTS IN THE FLOODPLAINS OF SYR DARYA AND ILI RIVERS IN THE TERRITORY OF KAZAKHSTAN
Authors: DUKENOV Z , RAKHIMZHANOV A , AKHMETOV R , DOSMANBETOV D , ABAYEVA K , BORISSOVA Y , RAKYMBEKOV Z , BEKTURGANOV A , MALENKO A , SHASHKIN A , TRUSHIN M
Published: November 2023

In the present era, assumptions on tugai forests consist of a complex floodplain ecosystem (reed-cattail thickets, gallery forests, halophytic shrubs, and grass biocenoses) of various ecological levels located from the water’s edge to the upper floodplains and riverine shafts. Anthropogenic transformations disrupted the natural dynamics of the tugai ecosystem. The presented study sought to characterize the current state of tugai forests in different regions of Kazakhstan to conduct monitoring of forest entomology and determine the reforestation potential of tugai plants in the floodplains of the Syr Darya and Ili rivers of Kazakhstan. The recent work focused on vital aspects associated with reinstating tugai forests. Special monitoring of forest pests progressed for the timely detection of their reproduction bulk, foci development, and plan extinction measures. The forest entomology monitoring results revealed the destruction of plants due to leaf-gnawing and gall-forming insect pests. A laid out 27 test areas investigated the dynamics of the undergrowth in tugai forests. The reproductive capacity of the plants, viz., Populus diversifolia, Elaeágnus angustifólia, Sálix acutifólia, and Salix wilhelmsiana, attained evaluation. Natural renaissance under the main forest-forming rocks’ characterization in tugai plantations was good.
THE MEDIATING ROLE OF INNOVATION ON THE RELATIONSHIP BETWEEN SUPPLY CHAIN MANAGEMENT AND COMPANY PERFORMANCE IN THE KINGDOM OF BAHRAIN
Authors: Alabdullah Tariq Tawfeeq Yousif , Kanaan-Jebna Abdulkarim
Published: November 2023

This research focuses on critical independent variables, including information quantity and quality sharing, and the adoption of lean practices within companies. It examines these variables to understand their effects on corporate performance using innovation as a mediator. Data from registered non-financial businesses in Bahrain are utilized, and Smart PLS is recommended for analysis. The study aims to unravel the intricate relationships among these variables in Bahrain's nonfinancial sector. Conceptually, it contributes to a deeper understanding of the interplay between information sharing, lean methods, innovation, and firm performance, with a focus on the mediating role of innovation. Practically, it offers insights for business leaders, policymakers, and professionals, enhancing awareness of information sharing, quality, and lean methods, thereby enabling informed decisions to improve corporate performance and foster innovation-driven growth. The uniqueness of this research lies in its holistic approach, examining the interconnectedness of information sharing, lean practices, innovation, and firm performance. Unlike previous studies that explored these aspects in isolation, this research integrates them into a comprehensive framework, enhancing its value to the field and potential impact on business operations. It serves as a valuable resource for academics, researchers, corporate executives, employees, and regulators. Academics and researchers benefit from its conceptual and empirical contributions, while corporate stakeholders gain practical insights for enhancing performance and promoting innovation. Regulators can leverage the findings to develop legislative structures that facilitate information sharing, quality, and lean practices in Bahrain's nonfinancial sector.
Suggestions for improvement in Vietnam employment laws in the context of gender equality
Authors: Tran Nguyen Quang Ha
Published: November 2023

Improving gender equality in the workplace is an urgent task for Vietnam Communist Party and the Government. Despite the ratification of international conventions on labour, women rights, as well as amendment to relevant domestic laws, it appears that the provisions have not satisfied the requirements set forth to combat discrimination at work against women. Through this article, the author intends to propose some ideas to improve the laws on the protection of the current female workers’ rights based on the 2012 Labour Code (amended and supplemented in 2019), related laws and sub–law documents.
Đánh giá hiệu quả điều trị bằng Amikacin qua theo dõi nồng độ thuốc trong máu của bệnh nhân tại Khoa Ngoại Thận - Tiết niệu, Bệnh viện Nhân dân Gia Định
Authors: Chi Nguyễn Thị , Hiền Trang Nguyễn Hồng , Thắm Phạm Hồng
Published: November 2023

Amikacin là kháng sinh thuộc nhóm aminoglycosid được sử dụng trong thực hành lâm sàng điều trị nhiễm khuẩn Gram (-) hiếu khí nặng đe dọa đến tính mạng người bệnh. Tuy nhiên, đây là kháng sinh phụ thuộc nồng độ và có khoảng trị liệu hẹp, độc tính cao nhất là độc tính trên thận và thính giác. Do đó, việc sử dụng amikacin hiệu quả và an toàn cần tuân thủ nghiêm ngặt về chỉ định, chế độ liều và phải được theo dõi hợp lí. Từ đó phát hiện sớm độc tính và điều chỉnh liều cho bệnh nhân. Khảo sát nồng độ amikacin trong máu của nhóm bệnh nhân độ tuổi trung bình (57,0 ± 15,3) tuổi, thời gian nằm viện (6,8 ± 2,4) ngày, với liều trung bình (13,6 ± 2,3) mg/kg/ngày cho kết quả nồng độ khoảng giữa (Cmid-level) ở thời điểm (9 - 12) giờ có 36,4 % bệnh nhân trong vùng 24 giờ, 59,1 % dưới ngưỡng phát hiện và 4,5 % trên vùng 24 giờ. Ở chế độ liều nhiều lần trên ngày (MDD) trong khoảng trị liệu, 87,5 % bệnh nhân có nồng độ đỉnh (Cpeak). Nồng độ đỉnh chế độ liều một lần trên ngày (ODD) chỉ có 9,1 % bệnh nhân đạt khoảng trị liệu. Nồng độ đáy (Ctrough) chế độ liều ODD bệnh nhân trên ngưỡng trị liệu là 23,1 %. Trong số 5 % bệnh nhân độc thận có 2,5 % suy thận cấp sau 3 ngày. Chưa phát hiện bất thường trên thính giác và tiền đình trong quá trình điều trị.
Xây dựng công thức điều chế nhũ tương dầu Thầu dầu để hướng dẫn sinh viên thực tập dạng bào chế dị thể lỏng
Authors: Tài Võ Thế Anh , Liêm Lôi Thông
Published: November 2023

Các thuốc nhuận tràng trên thị trường hiện nay đa số thuộc nhóm tổng hợp hoặc bán tổng hợp, còn các chế phẩm có nguồn gốc thiên nhiên lại rất hạn chế. Trong số các dược liệu sẵn có ngay tại Việt Nam, dầu Thầu dầu là một vị thuốc có tác dụng điều trị táo bón nhờ khả năng kích thích nhu động ruột. Khi sử dụng qua đường uống, dầu Thầu dầu gây cảm giác rất khó chịu cho người sử dụng do nguyên liệu này có bản chất là một loại dầu béo. Có thể khắc phục mùi và vị không mong muốn bằng cách điều chế thành dạng nhũ tương kiểu dầu/nước. Nghiên cứu này được tiến hành với mục đích xây dựng được công thức bào chế nhũ tương dầu Thầu dầu có thể tiến hành bào chế quy mô phòng thí nghiệm với các thiết bị sẵn có ở Bộ môn Bào chế công nghiệp dược. Nghiên cứu đã khảo sát được vùng tạo nhũ tương dầu Thầu dầu với 3 nhóm chất nhũ hoá khác nhau (Tween 80, Tween 80 – Span 80, Tween 20 – Span 80). Từ đó, lựa chọn được chất nhũ hoá phù hợp nhất là hỗn hợp Tween 80:Span 80 (90,65:9,35). Đã xây dựng được vùng tạo nhũ tương lỏng ổn định của dầu Thầu dầu. Nghiên cứu đã tiến hành khảo sát trên 10 công thức phù hợp với các tiêu chí của một nhũ tương dùng theo đường uống như thể chất lỏng, tỉ lệ hoạt chất cao nhất và chất nhũ hoá thấp nhất. Từ đó đưa ra công thức tối ưu để xây dựng bài giảng thực hành cho đào tạo dược.
Thiết kế và thực hiện cổng chuyển đổi LoRa - GSM giám sát các nút dựa trên công nghệ LoRa
Authors: Lil Hồ A , Minh Bùi Vũ
Published: November 2023

LoRa (Long Range Radio) là công nghệ không dây truyền dữ liệu tầm xa, tiêu thụ nănglượng thấp cho các ứng dụng M2M và IoT. Nhóm tác giả đã thiết kế và thực hiện cổngchuyển đổi (Gateway) LoRa– GSM (Global System for Mobile Communications) tíchhợp màn hình cảm ứng HMI (Human Machine Interface), để giao tiếp với người vậnhành thay thế cho một máy chủ LoRa. Cổng chuyển đổi sàng lọc và đưa dữ liệu lênmáy chủ IoT thông qua mạng di động GPRS/3G/4G tương thích với mọi địa hình khácnhau. Nút LoRa sử dụng cảm biến không dây dùng pin tiết kiệm năng lượng, đồng bộvới cổng chuyển đổi. Sản phẩm LoRa 433MHz đã được thử nghiệm ở hai vùng địahình: đô thị và nông thôn. Kết quả cho thấy cổng chuyển đổi đảm bảo yêu cầu kiểmsoát và truyền dữ liệu đạt độ tin cậy cao và ra quyết định điều khiển ổn định; có thểđược sử dụng trong công nghiệp, quan trắc môi trường nông nghiệp và y tế.
Xây dựng phương pháp phân tích irbesartan và hydroclorothiazid trong huyết tương người
Authors: Đào Lê Thị
Published: November 2023

Tóm tắtBài báo trình bày quá trình xây dựng và thẩm định một phần quy trình phân tích irbesartan (IRB) và hydroclorothiazid (HCTZ) trong huyết tương người bằng kĩ thuật LC-MS/MS. Phương pháp phân tích đã sử dụng telmisartan làm chuẩn nội để xác định irbesartan và hydroclorothiazid. Các chất phân tích và chất chuẩn nội được chiết bằng kĩ thuật chiết lỏng- lỏng với tert-butyl methyl ether, cột Gemini C18 (150 mm x 2 mm; 3 µm), pha động methanol – dung dịch đệm amoniformat 5 mM, pH = 5 (80:20), tốc độdòng 0,4 mL/min, thể tích tiêm mẫu 2 µL. Irbesartan, telmisartan được phân tích ở chếđộ ion hóa dương và hydroclorothiazid ở chế độ ion hóa âm. Theo hướng dẫn của USFDA và EMA về thẩm định phương pháp phân tích thuốc trong dịch sinh học, kết quảthẩm định một phần quy trình phân tích cho thấy quy trình đạt được tính đặc hiệu, hiệu suất chiết trên 95 %, tính tuyến tính trong các khoảng nồng độ dự định, đạt độ đúng và độ chính xác trong ngày và giữa các ngày, giới hạn định lượng dưới của IRB và HCTZ lần lượt là 0,005 µg/mL và 0,901 ng/mL. ® 2022 Journal of Science and Technology - NTTU
Nghiên cứu hoạt tính làm lành vết thương và kháng viêm của Lan Gấm (Anoectochilus formosanus Hayata) nuôi cấy mô
Authors: Khoa Nguyễn Thị , Phương Nguyễn Thị , Hân Phan Ngọc , Long Ngô Hoàng , Thăng Đỗ Đức , Giáp Đỗ Đăng
Published: November 2023

Lan Gấm (Anoectochilus formosanus Hayata) đã được chứng minh là loại dược liệu quý, có tác dụng kích thích hệ miễn dịch, chống tăng đường huyết và bảo vệ gan. Rất nhiều nghiên cứu đã sử dụng các cao chiết khác nhau để đánh giá hoạt tính sinh học của Lan Gấm. Trong nghiên cứu này, chúng tôi đánh giá in vitro hoạt tính làm lành vết thương của cao chiết chứa polysaccharide (AWE) và hoạt tính kháng viêm của cao chiết ethanol (AEE) từ Lan Gấm nuôi cấy mô tại Việt Nam. Kết quả cho thấy AWE ở nồng độ 100 μg/mL thể hiện hoạt tính làm lành vết thương sau 16 giờ xử lý trên mô hình nguyên bào sợi (fibroblast). Trong khi đó, AEE thể hiện khả năng kháng viêm trong thử nghiệm sản sinh NO trên tế bào RAW 264.7. Những hoạt tính in vitro của Lan Gấm thu được trong nghiên cứu sẽ tạo tiền đề cho các nghiên cứu tiếp theo trên mô hình in vivo.® 2022 Journal of Science and Technology - NTTU
Xây dựng và thẩm định quy trình định lượng vicenin 2 trong Rau đắng đất (Glinus oppositifolius (L.) DC., Molluginaceae)
Authors: Nguyễn Hiền Thị Thu , Hà Nhân Mỹ
Published: November 2023

Vicenin 2 là một flavonoid tự nhiên, có hoạt tính sinh học được chiết xuất từ nhiều loài thực vật, bao gồm Rau đắng đất (Glinus oppositifolius (L.) DC.,)  Các nghiên cứu gần đây đã chỉ ra rằng vicenin 2 có tác dụng chống viêm, bảo vệ gan, hạ đường huyết, chống ung thư, … Nghiên cứu đã tiến hành xây dựng và thẩm định quy trình định lượng vicenin 2 trong Rau đắng đất bằng HPLC-PDA  đồng thời thẩm định các chỉ tiêu của quy trình định lượng, từ đó đề xuất một quy trình mới để định lượng vicenin 2  trong Rau đắng đất. Quy trình sử dụng cột sunfire C18 (4,6 × 150 mm, 5 µm), phát hiện ở bước sóng 335 nm, pha động CH3CN–HCOOH 0,1 %. “Dược điển Việt Nam V” đã có chuyên luận về Rau đắng đất nhưng chưa có tiêu chuẩn định lượng nên đây sẽ làm tiền đề để xây dựng quy trình định lượng các hoạt chất trong dược liệu này. Có thể áp dụng rộng rãi quy trình này, góp phần đưa các phương pháp kiểm nghiệm hiện đại để kiểm soát chất lượng Rau đắng đất nói riêng cũng như kiểm soát chất lượng dược liệu và các chế phẩm từ dược liệu nói chung.

® 2023 Journal of Science and Technology - NTTU
Tác động của thái độ hướng tới giáo dục khởi nghiệp đối với ý định khởi nghiệp của sinh viên ngành Dược
Authors: Lê Bách Đăng Xuân
Published: November 2023

Nghiên cứu được thực hiện để đo lường ý định khởi nghiệp của sinh viên ngành Dược, Đại học Nguyễn Tất Thành. Mục tiêu nghiên cứu nhằm đánh giá các yếu tố hành vi, cảm nhận và nhận thức của sinh viên hướng tới giáo dục khởi nghiệp. Mô hình được xây dựng dựa trên Lí thuyết hành vi có kế hoạch (Theory of Planning Behaviour − TPB) và thừa kế mô hình từ các nghiên cứu trước. Kết quả của 400 khảo sát, thông qua phân tích PLS-SEM, cho thấy được yếu tố mạnh nhất tác động đến ý định kinh doanh, nền tảng gia đình có mối quan hệ tích cực đến thái độ hướng đến giáo dục, môi trường kinh doanh tác động đến ý định kinh doanh của sinh viên. Nghiên cứu thảo luận về kết quả phân tích mô hình, đề xuất về đóng góp thu được từ kết quả nghiên cứu. Kết quả nghiên cứu đưa ra các giải pháp giáo dục, xây dựng tinh thần kinh doanh khởi nghiệp của sinh viên ngành Dược.

® 2023 Journal of Science and Technology - NTTU
Biểu hiện, tinh sạch và đánh giá sơ bộ hoạt tính phân hủy nhựa PET của enzyme PETase tái tổ hợp
Authors: Phạm Trang Nguyễn Minh , Trần Diễm Hồng , Trần Hậu Thị , Phùng Hường Thị Thu
Published: November 2023

Nhu cầu xử lí rác thải nhựa polyethylene terephthalate (PET) đang ngày càng trở nên cấp thiết và quan trọng trong xã hội hiện đại. Hiện nay, việc xử lí rác thải PET dựa trên phương pháp phân hủy sinh học được xem là giải pháp bền vững để xử lí rác thải nhựa PET bằng cách sử dụng enzyme nguồn gốc từ vi sinh vật để xúc tác quá trình thủy phân PET. Nghiên cứu đã biểu hiện và tinh sạch thành công enzyme PETase thông qua kĩ thuật protein tái tổ hợp. Điều kiện tối ưu để biểu hiện PETase được xác định là cảm ứng 4 giờ 30 phút ở 30 ℃ với nồng độ IPTG là 0,01 mM. PETase sau tinh sạch thể hiện khả năng phân hủy nhựa PET hiệu quả với hoạt tính được tối ưu hóa khi bổ sung đồng thời glycerol 10 % và DTT 1 mM. Kết quả của nghiên cứu tạo tiền đề cho các nghiên cứu tiếp theo liên quan đến sản xuất enzyme phân hủy PET và các nghiên cứu liên quan đến protein tái tổ hợp để tái chế rác thải nhựa tại Việt Nam.

® 2023 Journal of Science and Technology - NTTU
The Role of Youth Activism in Facilitating Social Change: A Catalyst for Transformation in the Contemporary Era
Authors: Shah Majid Ali , Khan Zainullah
Published: November 2023

The article explores the critical part that youth activism plays in fostering social change within the current modern context. The research investigates how young activists have significantly influenced the process of altering social norms, political discourse, and cultural paradigms. This study thoroughly investigates the numerous facets and significance of youth activism in the modern day based on a thorough analysis of academic literature, empirical research, and practical examples. The study begins by looking at the development of young activism across time, placing it in relation to earlier social movements and highlighting its potential to change with the times. This remark emphasizes how social media platforms, in particular, have facilitated the capacity of young activists to connect, organize, and increase the reach of their messages on a global scale. The article also discusses the broad range of issues that young activists support, including gender parity, racial justice, and climate change, as well as the underlying causes that motivate them. The report also underlines how crucial it is for these devoted young to act as change agents by promoting policy adjustments, raising public awareness, and posing difficult questions about deeply rooted cultural norms and traditions. Lastly, it covers the challenges and obstacles young activists encounter, such as political pushback and personal exhaustion.
A Study on the Presence of Seobuyeo in Korean- Chinese Historical Materials
Authors:   The Academy of Real Korean History, Jee Yangmee
Published: November 2023

After the death of King Daeso of Dongbuyeo(東夫餘), Buyeo of the Nak’s Kingdom, which was initially sealed by Goguryeo(高句麗) as Buyeo King, is not a lord belonging to the Goguryeo Yeonnabu(椽那部). It can be confirmed through Korean-Chinese historical records that it was a royal state with independent military, diplomatic, and trade rights. King Daeso's younger cousin, who surrendered to Goguryeo, was not a heir to the throne, so he was not eligible to surrender by sacrificing his country, so it can be seen as an exile with his followers. Goguryeo, which wanted to become a new hegemonic power, established a new Buyeo as a result of King Daemusin's strategic proposal to expand its power by turning the royal family of Dongbuyeo into a reliable ally. The relationship with Goguryeo can be seen as a bandwagon alliance if analyzed by modern international political relations theory (IR). Buyeo became a target of the enemy and suffered serious damage when it participated in Goguryeo's hegemonic war, and Goguryeo's discriminatory support for this became the background for Buyeo to break its alliance with Goguryeo and collude with Houhan(後漢). King Uigutae(尉仇台), who rejuvenated Buyeo, secured the Daebang(帶方) area with Gonsongang(公孫康), the son of Gongsondo(公孫 度), the Taishou of Liaodong(遼東太守), and move the capital. For this Buyeo, which was in the Liaoseo(遼西) area from the 1st to the early 4th centuries, I suggest that it is necessary to classify it as 'Seobuyeo(西夫餘)' for the systematic organization of Buyeo history research.
Epistemological and conceptual problems in the scientific study of anomalous experience
Authors: Marques Stella Maris Souza , Goto Tommy Akira
Published: November 2023

Anomalous experience is defined as an unusual experience and although it is experienced by a substantial number of people in a population, it differs from ordinary experience and thus from commonly accepted explanations of reality. It is essential to point out that there are reports of an enormous and complex variety of so-called anomalous experiences, encompassing a diversity of experiences, leading to a conceptual difficulty. To this end, we carried out a reflection, based on theoretical and bibliographical studies in the concept of anomalous experience, in order to explore the terminologies concerning the anomalous and to verify the reason for the difficulty of consensus about the theme. Exploring the existing terminologies in relation to the anomalous experience, a difficulty of clarity and conceptual systematization guided in its nature was identified in appropriation and conceptual use. In our discussion we explain certain historical-epistemological points of nomenclatures and areas of knowledge used in diverse experiences, specifically those linked to anomalies, such as the parapsychological experiences marked by Parapsychology and the religious experiences by the Psychology of Religion and Phenomenology of Religion; in order to problematize the difficulty that Anomalistic Psychology presents in the study and differentiation of these experiences.
Uncommon clinical features of juvenile primary hypothyroidism
Authors:   Senior Resident, Department of Endocrinology, SSH, GMC, Srinagar, India., Alam Md Ejaz
Published: November 2023

This case study presents an 18-year-old boy with severe short stature and distinct physical features, including facial abnormalities, skeletal deformities, and intellectual impairment. Further investigations revealed hypothyroidism, autoimmune thyroiditis, and delayed bone age. Treatment with levothyroxine replacement therapy was initiated. The study highlights the importance of detection and management of hypothyroidism in individuals with short stature and associated features.
Embolization Using the Novel Menox Liquid Embolic System for Arteriovenous Fistulas
Authors:   Interventional Radiology Department, Republican Vilnius University Hospital, Siltnamiu St. 29, 04130 Vilnius, Lithuania., Sirvinskas Audrius
Published: November 2023

Thrombosis in the brain venous network may be one of the reasons for cerebral infarction related to arterial disease, which becomes a cause of concern as many cases of cerebral venous thrombosis (CVT) lead to mortality.
Hypoglycemia imitating cardiac ischemic symptoms A case report and review of literature
Authors:   Adult echocardiography Department, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran., Fini Haniye Hajiali
Published: November 2023

Ischemic heart disease is the most common cause of mortality in all low and high-income countries. Diabetes mellitus is also a major public health challenge increasing rapidly worldwide and is reported as an equivalent to coronary heart disease (CHD) in some studies. Hypoglycemia is a common complication in diabetic patients that can stimulate the sympathetic nervous system in its severe form, eventually leading to the destabilization of atherosclerotic plaques and cardiovascular events. Therefore, preventing hypoglycemia is crucial in diabetic patients, especially those with a previous history of CAD, in order to prevent cardiovascular events. In this study, we report a diabetic patient presented with multiple hypoglycemic episodes and chest pain.
An illustration of clinical warts before and after treatment with the unani kit medicines in general OPD A case study
Authors:   Colocation Research Center, RRIUM, Mumbai, J.J. Hospital, Byculla, Mumbai, India., Bano Humaira
Published: November 2023

The Unani system of medicine is an ancient, rich, and comprehended system of medicine, with knowledge propounded in the course of complicated, chronic, and rare disease treatments. The aim of this study is to bring its effectiveness and safety outcomes to light. This is a case study based on a 9-year-old body, with complaints of a small growth on the little finger, which was cured with 100% effectiveness with the Unani kit medicine of Majoon Ushba and Habbe Musaffi khoon and sprinkling powder of Mazu (Quercus infectoria Oliv), Shibbe-yamani (Alum), and sandal wood powder. It creates a hypothesis to bring a clinical trial to a large scientific scale for better and more significant results.
Nanomaterials as drug delivery agents for overcoming the blood-brain barrier: A comprehensive review
Authors: Kulkarni Mangesh , Patel Krishi , Patel Ayush , Patel Swayamprakash , Desai Jagruti , Patel Mehul , Shah Umang , Patel Ashish , Solanki Nilay
Published: November 2023

Background and Purpose: The blood-brain barrier (BBB), a critical interface of specialized endothelial cells, plays a pivotal role in regulating molecular and ion transport between the central nervous system (CNS) and systemic circulation. Experimental Approach: This review aims to delve into the intricate architecture and functions of the BBB while addressing challenges associated with delivering therapeutics to the brain. Historical milestones and contemporary insights underscore the BBB's significance in protecting the CNS. Key Results: Innovative approaches for enhanced drug transport include intranasal delivery exploiting olfactory and trigeminal pathways, as well as techniques like temporary BBB opening through chemicals, receptors, or focused ultrasound. These avenues hold the potential to reshape conventional drug delivery paradigms and address the limitations posed by the BBB's selectivity. Conclusion: This review underscores the vital role of the BBB in maintaining CNS health and emphasizes the importance of effective drug delivery through this barrier. Nanoparticles emerge as promising candidates to overcome BBB limitations and potentially revolutionize the treatment of CNS disorders. As research progresses, the application of nanomaterials shows immense potential for advancing neurological therapeutics, albeit with careful consideration of safety aspects.
Postoperative rehabilitation of compartment syndrome following fasciotomy
Authors: Altan Lale
Published: November 2023

Compartment syndrome can be defined as an increase in pressure in an anatomical compartment in the body resulting in muscle and nerve damage. Acute compartment syndrome mostly develops after crushing traumas and fractures to the extremities and is a condition that requires urgent intervention. Fasciotomy of the affected extremity segment in the early stage of the compartment syndrome is the gold standard in treatment of crush injury. Rehabilitation after fasciotomy is extremely important in regaining extremity functions. In this review, we discuss current approaches to compartment syndrome and rehabilitation principles following fasciotomy.
Effect of protein phosphorylation inhibitor on production of parthenogenetic caprine embryos
Authors: KHARCHE S D , GOEL A K , JINDAL S K , GOEL PUJA , KOUAMO JUSTIN , SARSWAT SONIA
Published: November 2023

The objective of the present study was to compare the effect of different concentrations of 6-Dimethylaminopurine (6-DMAP) treatment in chemical activated oocytes to compare the developmental potency of parthenogenetic caprine embryos. Morphologicaly matured oocytes were denuded and activated with 5 μm calcium ionophore (ionomycin) for 5 min. Activated oocytes were randomly divided into 5 groups: Group 1 oocytes were cultured in modified Charles Rosenkrans medium (mCR2aa), without DMAP treatment, group 2 cultured in mCR2aa with 2.5 mM DMAP, group 3 cultured in mCR2aa with 5 mM DMAP, group 4 cultured in mCR2aa with 10 mM DMAP, group 5 cultured in mCR2aa with 20 mM DMAP for 4 h. The presumptive zygotes of 5 groups were washed and cultured in the embryo development medium. Development of parthenotes was observed at every 48 h till day 12 post insemination. The percentage of cleavage, morula, blastocyst and hatched blastocyst production in groups 1, 2, 3, 4 and 5 were 61.76, 6.67, 0.00 and 0.00; 59.79, 27.43, 10.62 and 0.00; 72.43, 41.62, 10.66 and 1.52; 64.61, 50.44, 7.83 and 0.00; 63.19, 19.42, 3.88 and 0.00% respectively. Results indicated that 5 mM DMAP treatment for chemically activated oocyte is the best treatment for development of parthenogenetic caprine embryos. In conclusion, it can be stated that for the production of caprine parthenogenetic embryos in vitro, concentration of protein phosphorylation inhibitor plays an important role in the activation treatment. Optimized activation protocols could enhance the production of viable parthenogenetic embryos.
Legal aspects of the use of medical cannabis in Poland compared to other countries: Comparative legal analysis
Authors: Marta Woźniak
Published: November 2023

The importance of this issue is that there is an increasing demand for the use of medical marijuana in treatment where methods based on traditional medicine have failed. The aim of the article is the analysis and evaluation of the legal regulation of treatment with preparations containing medical marijuana in Poland against the background of trends in other countries. The study employs a dogmatic and black-letter methods of analyzing the provisions of the law in force in Poland and also a comparative method. Studies have shown that the systems of countries in Europe and the world vary in this regard. When it comes to the medical use of marijuana, three solutions are possible: a liberal model, where the patient can grow the plant himself, a moderate model, which relies on the possibility of obtaining a drug based on medical marijuana with a prescription. The third model is based on the impossibility of medical use of marijuana. The Polish legal model is moderate and consists of the possibility of obtaining a medical marijuana-based drug by prescription. Independent cultivation under this model is not possible. A business entity that intends to cultivate cannabis for medical purposes must have the appropriate permit from the competent state authority. This solution (present in many other countries) is characterized by a balance between legalization of medical marijuana and drug prevention. Under the Polish legal model, cannabis cultivation remains under state supervision. Medical marijuana is available to the patient, but access to it is strictly regulated. This is not a liberal legalization model, as availability depends largely on the doctor. Practical results show a progression in the availability of medical marijuana medicines compared to previous years. The legislature is open to change, but out of caution against the proliferation of drug offenses, it has not decided on greater liberalization
Risk and subjective rationality as decision-making factors in the professional activity of Police Officers
Authors: Masian Anna
Published: November 2023

The relevance of the study is conditioned by the lack of development of the problem of forming the decision- making ability at the stage of professional training and the need to improve the modern daily practice of future law enforcement officers to ensure the accuracy and timeliness of decisions made against the background of a constant increase in the volume and complexity of incoming information. The purpose of the study was to determine the conceptual basis for the influence of subjective rationality and risk readiness in the decision- making system in the professional activities of police officers. The paper uses the method of comparative and correlation analysis, and statistical analysis of primary data. According to the results of the study, significant correlations were established between rationality and risk factors in decision-making among police officers in groups with different levels of experience and professionalism. The current study focuses on intra-group variations in risk maximisation and the use of rational traits, particularly vigilance, procrastination, avoidance, and over-vigilance in decision-making. These psychological phenomena are explained by studying the main group of law enforcement officers (n=116), divided by the sample according to the criterion of experience in practice (n=59, n=57). A significant difference and psychological difference in the decision-making process component was found between groups with and without practical work experience in law enforcement. This provides an opportunity for further expansion and development in this area, defining the main approach to creating professional skills, forming the ability to make decisions in law enforcement officers without practical experience, and consolidating the basic skills of law enforcement officers with practical experience. The practical significance of the study lies in the prospect of developing psychocorrective programmes and trainings aimed at various employees of law enforcement agencies, depending on the practical experience gained and the area of activity. The research materials can be used in the process of optimising the educational process in professional institutions
Advancements and Future Directions of Immunotherapy in Cancer Treatment
Authors: Zhang Wanqing , Liu Qishan , Zhou Tianxiang
Published: November 2023

Immunotherapy has revolutionized cancer treatment by harnessing the power of the immune system to target and eliminate cancer cells. This approach has shown remarkable success in various cancer types, including melanoma, lung cancer, and breast cancer. However, challenges and limitations exist, such as resistance mechanisms and immune-related adverse effects. To overcome these challenges, future directions in immunotherapy focus on combination therapies, targeting novel immune checkpoints, and identifying reliable biomarkers and predictive factors. These advancements aim to improve treatment outcomes and personalize immunotherapy for individual patients. Continued research and clinical trials in these areas will shape the future of immunotherapy and contribute to the fight against cancer.
Combining ability studies for yield and its component traits in safflower (Carthamus tinctorius L.)
Authors: P B WADIKAR  , S L DHARE  , S L WAGHMODE
Published: November 2023

Combining ability for ten characters was studied by crossing three lines and five testers in line x tester fashion.The estimates of SCA variance were not higher than GCA variance in most of the traits indicating preponderance of non-additive gene action. The line, GMU-2720 had significant positive GCA effects for seed yield/plant, number of branches, number of capitula/plant, number of seed/capitulum, and oil content whereas significant negative GCA effects for days to 50% flowering, days to maturity and plant height. The cross, GMU-2720 x GMU-3423 and JMU1339 x PBN-96 were best for majority of the characters and thus identified as promising cross combinations for further improvement programme in safflower.
Identification of new molecular markers for low glucosinolates in Indian mustard (Brassica juncea L. Czern and Coss.)
Authors: H D PUSHPA  , D K YADAVA  , SUJATA VASUDEV  , V VINU  , CHANDANABEHERA  , NAVEEN SINGH
Published: November 2023

The study was carried out to identify molecular markers linked to low glucosinolates in Brassica juncea using recombinant inbred lines developed from cross between Pusa Mustard 21 × EC597325. Parental polymorphism studies with 594 SSR markers, revealed 62 informative markers. The bulk segregant analysis (BSA) revealed four microsatellite markers differentiating both the parental lines and the high and low glucosinolates bulks, hence putatively linked to the genomic regions controlling low glucosinolates.
Studies on variability analysis in groundnut (Arachis hypogaea L.)
Authors: R G GAWALI  , A M MISAL  , V G SONAWANE
Published: November 2023

The present investigation in groundnut was undertaken to study the extent of genetic variability for yieldcontributing characters in eighteen groundnut genotypes including three checks. These were evaluated at Oilseed Research Station, Latur during kharif 2016. The observations were recorded on selected five plants for seventeen characters. The estimates of genotypic and phenotypic coefficient of variation indicated that maximum GCV and PCV were observed for number of pods/plant, kernel yield/plant, pod yield/plant, harvest index, total sugar, thrips incidence, trichome frequency, SMCR. The estimates of variability were appreciably high for harvest index, number of pods/plant, kernel yield/plant and pod yield/plant, total sugar, and trichome frequency.
AMS-1001 (PDKV yellow gold): A new high yielding, charcoal rot and yellow mosaic virus disease resistant soybean variety
Authors: S S NICHAL  , P V PATI  , G D CHANDANKAR  , M S DANDGE  , Y V INGLE  , S S MUNJE  , H H DIKEY
Published: November 2023

Soybean variety AMS-1001 is a high yielding mutant of JS-93-05. In multi-location trials, AMS-1001 recordedyield increase over state check MAUS-71 by 24.17% and national check JS-335 by 20.58%. In state multilocationtrials AMS-1001 recorded 36.01%, 30.58% and 33.82% increase yield over JS-335, JS-97-52 and MAUS-71,respectively. AMS-1001 has also given 23.90% higher seed yield over check variety JS-335, in adaptive trials on farmer's field. This culture has shown highly resistant reaction to charcoal-rot and YMV diseases. AMS-1001differentiated from other soybean varieties using molecular markers and primer Glysatt-180 was found specific to the sample AMS-1001 and can be used for its identification. Considering its yield superiority and resistance to diseases the SVRC has released AMS-1001 for Maharashtra state. The national identity of this variety isIC-626343.
Evaluation of advanced breeding lines of sesame (Sesamum indicum L.) for seed yield and oil content
Authors: A B M SIRISHA  , S K HASEENA BANU  , S V S GANGADHARA RAO
Published: November 2023

The present investigation was carried out to evaluate the advanced breeding lines in sesame for seed yield and oil content. The experiment was conducted during kharif 2018, with eight entries (seven advanced breeding lines and one check Sarada) in randomized block design, with plot size of 3.0 x 4.5 m and spacing of 30 x15 cm. Data was recorded on the parameters viz., days to maturity, seed yield (kg/ha), oil percent and oil yield kg/ha. Among all the entries tested, YLM-146 and YLM-142 recorded significant and highest seed yield 1017 kg/ha and 963 kg/ha, respectively compared to the check Sarada (YLM-66).
Assessment of genetic diversity in sunflower germplasm lines
Authors: S B SAKHARE  , RUPALI CHAKRABORTY  , SANGITA FATAK  , N J WANKHADE
Published: November 2023

The present study was undertaken to estimate the extent of genetic diversity among germplasm lines and toidentify genetically diverse lines of sunflower for their further exploitation. Thirty- three genotypes were grouped into eight clusters by using Tocher’s method. On the basis of average inter cluster distance, cluster mean and mean performance of genotypes, 16 superior crosses have been suggested which are expected to yield desirable genetic gain in breeding programme.
Character association and genetic divergence study in elite breeding lines of groundnut (Arachis hypogaea L.)
Authors: JAYASHREE KAR  , ANKITA JENA
Published: November 2023

Character association and genetic divergence were carried out in a set of elite breeding lines of groundnut. Podyield/plant showed significant positive correlation with days to first flowering, plant height, total number ofgynophores/plant and 100 kernel weight both at phenotypic and genotypic level. Biological yield and harvest index had higher positive correlation as well as direct positive effect with seed yield. Thirty genotypes were distributed into eight clusters out of which four were mono-genotypic. Cluster I consisted of 16 genotypes, whereas cluster II, III and IV consisted four, four and two genotypes respectively. Cluster VIII showed highest pod yield/plant followed by cluster IV. Inter cluster distance between cluster VI and VIII was highest, whereas lowest inter cluster distance was observed between cluster III and I. Pod yield /plant contributed maximum towards genetic divergence followed by yield (q/ha).