bluuebunny/crossref_metadata_2025 huggingface dataset:
Lehetséges lehetséges világaink
Authors: Alberti Gábor , Dóla Mónika , Kárpáti Eszter , Kleiber Judit , Viszket Anita , Szeteli Anna
Published: January 2022

A ℜeALIS reprezentacionalista gyökereinek felvázolását és a kurrens
dinamikus-pragmatikai célrendszer (Farkas–Roelofsen 2017) feltérképezését
követően azt az adósságot kívánjuk törleszteni, hogy a kérdő mondattípus
pragmaszemantikai jellemzéséhez hasonló alaposságú leírást (Alberti et al.
2019a) kapjon a felkiáltó és az óhajtó, valamint a felszólító és a
kijelentő mondat is. E mondattípusok pragmaszemantikai jellemzésének finom
részleteivel kívánunk szolgálni, végső soron az emberi kommunikációs
tevékenység mentális megalapozását jelentő elmebeli
lehetségesvilág-struktúra feltérképezéséhez járulva hozzá. Azt is
szemléltetjük, hogy a diskurzusjelölők hogyan vonnak be újabb világokat e
mentális térbe. Végül (az addigi feladói perspektíva helyett) a címzetti
perspektívából vesszük szemügyre a hallgatói perlokúciós műveletek révén
tovább gyarapodó „lehetséges lehetséges világainkat”.
Diagnóstico do uso da água subterrânea como subsídio à gestão municipal de recursos hídricos
Authors: Benetello Thalita , Ezaki Sibele
Published: January 2022

A região que abrange as bacias hidrográficas dos rios Piracicaba, Capivari e Jundiaí (PCJ) demonstra uma crescente demanda na explotação e uso das águas subterrâneas, que acompanha o aumento populacional e da urbanização. Levantamentos regionais indicam cenários de limitações na disponibilidade hídrica subterrânea associados a grandes volumes de águas extraídos, mostrando a necessidade de um acompanhamento, também em escala local, sobre a situação do uso dos recursos hídricos. Nesse sentido, este trabalho teve como proposta avaliar os dados existentes e disponíveis sobre a água subterrânea, em escala municipal, com o intuito de elaborar um diagnóstico sobre a sustentabilidade do uso da água. Selecionou-se o município de Sumaré-SP, por estar inserido em área crítica quanto à disponibilidade hídrica e por contemplar no seu Plano Diretor diretrizes para a gestão ambiental integrada. A partir de dados de cadastros oficiais de poços, foram avaliados os aquíferos mais explotados quanto a: potencialidade hídrica (vazões e capacidades específicas médias e medianas, profundidade dos poços e dos níveis d’água), finalidades de uso da água, densidade de poços e intensidade de extração de água subterrânea e saldo hídrico. A constatação de existência de áreas onde ocorre déficit hídrico levou a recomendações como o aprofundamento nos estudos hidrogeológicos, assim como o acompanhamento da evolução da situação da explotação hídrica no município e de ocorrência de conflitos de uso.
Macro-TSH in patients with primary hypothyroidism due to autoimmune thyroiditis
Authors: Saribekian A. G. , Petrenko D. A. , Trukhina D. A. , Kuzmin A. G. , Dzeranova L. K. , Nikankina L. V. , Kolesnikova G. S.
Published: January 2022

Thyroid stimulating hormone (TSH) is one of the key indicators in the diagnosis of the thyroid gland functional disorders. Minor changes in TSH concentration make it possible to suspect thyroid dysfunction even before clinical manifestations, which increases the value of correct and timely measurement of it. In the clinical practice, an endocrinologist often encounter the well-known phenomenon of macroprolactinemia; a much less common phenomenon is macrotyrotropinemia (macro-TSH). The presence of macro-TSH complexes can be suspected when the serum detects atypically high TSH values with reference values of FT4 without any signs of hypothyroidism. Since the phenomenon is based on an autoimmune mechanism, macro-TSH can often be detected in patients with autoimmune thyroiditis (AIT). This article presents clinical cases of patients with a combination of the macro-TSH phenomenon and primary hypothyroidism due to AIT.
MODERN METHODS FOR FINISHING CYCLOIDAL SCREW SURFACES
Authors: Akulinichev P. D. , Albov M. A. , Zenin I. O. , Gemba I. N.
Published: January 2022

The work is devoted to the presentation of the results of the analysis of modern methods of finishing processing of cycloidal screw surfaces of single-screw machines of volumetric type. A comparison of the operating conditions of parts with cycloidal helical surfaces is carried out, and the main technical requirements for finishing are identified.
FEATURES OF TRAINING STUDENTS IN SPECIALTY “DESIGN OF TECHNICAL AND TECHNOLOGICAL COMPLEXES” AT BAUMAN MOSCOW STATE TECHNICAL UNIVERSITY
Authors: Vasil’iev A. S. , Kiselev V. L. , Kravchenko I. I. , Spiridonov O. V.
Published: January 2022

The actuality and urgent need for training of qualified engineers in the specialty “Design of technologicalmachines and complexes” for the Russian economy is shown. The leading role of the BMSTU in the development of program for this specialty is revealed. The main features of training engineers in the specialty “Design technological machines and complexes” in BMSTU are presented.
Efek Kepemilikan Institusional, Profitabilitas, Ukuran Perusahaan dan Pertumbuhan Penjualan Terhadap Nilai Perusahaan dengan Struktur Modal Sebagai Variabel Intervening (Studi Pada Perusahaan Manufaktur Di BEI Tahun 2013-2017)
Authors: Simanjuntak Tagora Bangkit Pahala , Pangestuti Irene Rini Demi
Published: January 2022

Tujuan penelitian ini adalah untuk menguji pengaruh kepemilikan insitutisional, profitabilitas, ukuran perusahaan dan pertumbuhan penjualan terhadap nilai perusahaan dengan struktur modal sebagai variabel intervening (studi di Perusahaan Manufaktur Listing di Bursa Efek Indonesia sejak 2013 sampai periode 2017). Sampel dalam penelitian ini adalah perusahaan manufaktur sesuai dengan kriteria yang ditetapkan. Analisis regresi linear berganda dilakukan dengan didasarkan pada hasil analisis data. Penelitian ini menyimpulkan beberapa hal sebagai berikut: Variabel kepemilikan institusional, profitabilitas dan ukuran perusahaan berpengaruh negatif signifikan terhadap struktur modal. Pertumbuhan penjualan tidak berpengaruh terhadap struktur modal. Kepemilikan institusional tidak berpengaruh terhadap nilai perusahaan. Profitabilitas, ukuran perusahaan dan pertumbuhan penjualan berpengaruh positif signifikan terhadap nilai perusahaan. Struktur modal berpengaruh negatif signifikan terhadap nilai perusahaan. Struktur modal dapat memediasi pengaruh kepemilikan institusional, profitabilitas dan ukuran perusahaan terhadap nilai perusahaan. Struktur modal tidak dapat memediasi pengaruh pertumbuhan penjualan terhadap nilai perusahaan.
UMKM Naik Kelas: Mengkonstruksi Sebuah Desain Faktor Determinant Berluaran Perkembangan Usaha (Studi pada UMKM di Kota Semarang)
Authors: Sijabat Rauly
Published: January 2022

UMKM is recognized as having an important role as an economic buffer through its contribution to national GDP and unemployment reduction. However, the acknowledgment, the reality is not linear with improving business performance and the development of the UMKM business itself. Even though it has contributed greatly, its performance and development still cannot compete with MSMEs in other Asian countries. This phenomenon encourages a study to empirically model determinant factors that influence the development of MSME businesses. The result is an empirical model of business development that is explained by business performance, entrepreneurial competence, personal factors, organizational factors and environmental factors. To meet the data needs of these variables, interviews were conducted using a questionnaire. Testing empirical models and hypotheses through the research data obtained was carried out using the Structural Equation Modeling (SEM) approach. The findings from the test results are that business development is explained by business performance. While business performance is determined by entrepreneurial competence, personal factors and environmental factors. Organizational factors cannot be proven in this study.
Analisis Sentimen Pemberitaan Vaksin Covid-19 dan Kaitannya dengan Perubahan Harga Saham Emiten Farmasi
Authors: Rai Abyan
Published: January 2022

Pandemic of Covid-19 that entered Indonesia in early March 2021 limited activities in various sectors. This condition causes the economy in Indonesia to become unstable and even experience a recession in 2020. Vaccines produced by pharmaceutical companies are one of the government's ways to improve not only health but also economic conditions in Indonesia. Various reports on the Covid-19 vaccine have caused investor reactions in the capital market, one of which is in the pharmaceutical sector itself as a producer of the Covid-19 vaccine. Using the Lexicon-based method and Pearson correlation, this study aims to analyze the sentiment of the Covid-19 vaccine coverage and analyze the relationship between these sentiments and the stock price of pharmaceutical issuers. Covid-19 vaccine news data is collected from Twitter for 22 days with 500 tweets per day. The tweets were categorized into positive, negative, or neutral sentiments using the Lexicon-based method. The results of this study indicate that the media provides more positive sentiment towards the Covid-19 vaccine. A unidirectional relationship exists between the sentiment in the Covid-19 vaccine coverage and one of the stock prices of a pharmaceutical issuer.
Analisis Enterprise Resource Planning (ERP) Terhadap Business Model Inovation (BMI)
Authors: Pontoh Grace Theresia , Syamsuddin Syamsuddin , Irwan Rezkiyana Ulfha , Astari Fitrah
Published: January 2022

This research was conducted at PT. Telekomunikasi Indonesia Tbk, which has a branch in Makassar with the aim of knowing how much influence Enterprise Resource Planning (ERP) has on Business Model Innovation (BMI). This study uses the interview method. Based on the research results, an ERP system helps automate various processes in a company both in automating customer management, financial management, and employee management. This ERP system software helps provide any information or data in realtime with a high degree of accuracy. The ERP system used by PT. Telekomunikasi Indonesia Tbk is a SAP R / 3 Enterprise.
Analisis Bibliometrik Trend Penelitian Covid-19 di Indonesia Pada Bidang Bisnis dan Manajemen
Authors: Nurfauzan Muhammad iqbal , Faizatunnisa Hanani
Published: January 2022

Tujuan penelitian ini untuk menganalisa bagaimana penelitian tentang dampak covid-19 pada bidang bisnis diklasifikasikan beserta trendnya dan untuk mengetahui topik apa yang dapat dijadikan variabel penelitian dimasa yang akan dating. Metode penelitian adalah tinjauan pustaka dengan menggunakan pendekatan analisis bibliometrik dimulai dari pendefinisian kata kunci ‘Covid-19’ dan ‘Jurnal’ pada aplikasi Publish or Perish dengan Google Scholar sebagai database. Setelah dilakukan penyempitan hasil dengan memilih topik khusus pada ‘bisnis dan manajemen’, diperoleh 32 artikel terkait untuk ditinjau dari 125 artikel hasil pencarian awal. Kemudian disusun meta data menggunakan aplikasi Mendeley, aplikasi Vosviewer digunakan untuk membuat visualisasi trend penelitian. Hasil penelitian menunjukkan jika klasifikasi penelitian mengenai covid-19 pada bidang bisnis dan manajemen dibagi menjadi 3 cluster dengan topik yang berpusat pada sektor bisnis yang terdampak seperti pariwisata, UMKM, dan pasar tradisional. Kinerja karyawan, pemutusan hubungan kerja, dan WFH merupakan cluster pada bidang manajemen. Penelitian ini terbatas oleh jumlah dan kurangnya variasi topik penelituan artikel yang ditinjau.
Studi Tentang Kepuasan Konsumen di Toko Emas Pusaka Sukorejo Kendal
Authors: Amalina RA Nur , Sukresna I Made , Sugiharto J.
Published: January 2022

Penelitian ini bertujuan untuk menganalisis pengaruh kualitas barang emas dan kualitas layanan terhadap WOM (Word Of Mouth dengan menggunakan kepuasan konsumen sebagai variabel mediator (intervening) studi pada toko emas pusaka mas Sukorejo Kendal. Kualitas barang emas merupakan hal yang menjadi pertimbangan konsumen dalam melakukan pembelian pada Toko emas pusaka Sukorejo Kendal.Responden dalam penelitian ini adalah konsumen yang melakukan transaksi di toko emas pusaka mas Sukorejo Kendal. Data dikumpulkan melalui metode kuisioner yang diisi secara mandiri oleh 155 responden yang dipilih dengan metode non probability sampling dimana responden telah melakukan pembelian atau transaksi di toko emas pusaka mas Sukorejo Kendal. Metode analisis yang digunakan adalah analisis Structural Equation Modelling (SEM) yang dijalankan dengan program AMOS.Hasil pengujian hipotesis dengan SEM menunjukkan bahwa : 1. Kualitas barang emas berpengaruh positif terhadap kepuasan konsumen, 2. Kualitas layanan berpengaruh positif terhadap kepuasan konsumen, 3. Kepuasan konsumen berpengaruh positif dan signifikan terhadap WOM 4. Kualitas layanan berpengaruh positif terhadap WOM studi pada toko emas pusaka mas Sukorejo Kendal.
Analisis Kepuasan Pelanggan Menggunakan Mix Method (Studi Kasus pada Lettice Clinic Tanjung Pinang)
Authors: Sukarnadi Natalia , Raharjo Susilo Toto
Published: January 2022

This research conducted to analyzed Lettice Clinic’s patient satisfaction index at Tanjung Pinang. Lettice Clinic is a beauty clinic that gives treatment services contains pharmacy installation and beauty skin treatment and also beauty natural like eyelash extention, filler, brow tatoo, etc.This reseach used mix method, first method using IPA (importance performance analysis) quantitative analysis conducted on 100 samples who visit Lettice Clinic and second method is conducted by interview to 3 Lettice Clinic’s Informan. Data was collected by questionary and qualitative research manuscript.The finding through mix method research are Quadrant I (main priority) consist of services attribute employee existing; fast, ontime and clear treatment; and problem solving. Quadrant II (achievement surviving) consist of service attribute physical facility, complaint handling, accuracy and in-depth explaining ability. Quadrant III (Low Priority) consist of service attribute employee readiness, client understanding ability and able to self-placement. Quadrant IV (Too Much) consist of service attribute employee appearance that too good look, too accurate information giving, too fast responses, accuracy command and client treatment. While in-depth interview result showed generally consistent with IPA analysis result.
Analisis Faktor-Faktor yang Mempengaruhi Preferensi Konsumen Terhadap Keputusan Pembelian Obat Generik (Studi Pada Konsumen di Apotek Kimia Farma Pandanaran Kota Semarang)
Authors: Ronauli Laura Natalia , Indriani Farida
Published: January 2022

Obat generik merupakan obat yang diproduksi setelah berakhirnya masa paten yang melindungi obat paten. Penggunaan obat generik di Indonesia terus meningkat setiap tahun, yang terlihat dari peningkatan penjualannya. Pembelian obat generik tidak terlepas dari pengaruh berbagai faktor. Penelitian ini bertujuan untuk menganalisis pengaruh pengetahuan konsumen tentang obat generik, kelompok referensi, kualitas, dan persepsi terhadap harga terhadap preferensi konsumen untuk membeli obat generik di Apotek Kimia Farma Pandanaran Kota Semarang melalui metode quantitative approach menggunakan teknik non-probability purposive sampling. Analisis dilakukan menggunakan pemodelan persamaan Structural Equation Modeling (SEM) melalui SPSS dan AMOS dengan menggunakan 5 variabel yaitu pengetahuan, kelompok referensi, kualitas, persepsi terhadap harga, dan preferensi konsumen melalui 29 indikator yang ada pada 5 variabel tersebut. Hasil penelitian ini yaitu 5 hipotesis yang diajukan diterima dimana pengetahuan (H1), kelompok referensi (H2), kualitas (H3), persepsi terhadap harga (H4) berpengaruh positif dan signifikan terhadap preferensi konsumen untuk membeli obat generik di Apotek Kimia Farma Pandanaran Kota Semarang. Preferensi konsumen (H5) berpengaruh positif dan signifikan terhadap keputusan pembelian obat generik di Apotek Kimia Farma Pandanaran Kota Semarang. Hasil penilaian konsumen yang menjadi responden pada masing-masing indikator dapat menjadi masukan untuk upaya meningkatkan penjualan obat generik.
Event Flash Sale Terhadap Keputusan Belanja Online Selama Pandemi Covid-19 Pada Marketplace Serta Implikasi Pada Kepuasan Konsumen di Kota Malang
Authors: Rachmadi Kartika Rose , Arifin Rois
Published: January 2022

Covid-19 pandemic in Indonesia requires business people to innovate in business. Not only one or two sectors but many sectors, one of which is the business and trade sector, which causes their income to decline. The state of this pandemic is one of the driving factors for the creation of competition for all sectors, and in this case, business people. One of is the sales promotion program like flash sale event, including the marketplace. In the other hand, it can also see how online shopping behavior at flash sales events and its effect on consumer satisfaction. The research method uses quantitative using explanatory research techniques involving 200 respondents with accidental sampling. Distribution of questionnaires using Google forms while still paying attention to government policies in the form of social distancing and psbb. The results showed that the three variables in this study such as flash sales, online shopping decisions and satisfaction had a significant positive effect on the marketplace during the pandemic in Malang City.
Metodologías y didácticas en el departamento de ciencias básicas de la Universidad de La Salle en tiempos de pandemia
Authors: Rendón Fernández Margarita Rosa , Zapata Lesmes Angela Cristina
Published: January 2022

En este capítulo se presentan, de manera resumida, algunos apartes de la historia del Departamento de Ciencias Básicas y sus apuestas metodológicas y didácticas desde las áreas de conocimiento de física, química y matemáticas en medio de la pandemia con las respuestas de 20 docentes a un instrumento diseñado con tres elementos principales: (a) el propósito de la metodología, (b) los encuentros virtuales en perspectiva de las estrategias didácticas, y (c) las recomendaciones generales desde lo vivido en el desarrollo de cada espacio académico.
Novel predictor of the occurrence of DKA in T1DM patients without infection: A combination of neutrophil/lymphocyte ratio and white blood cells
Authors: Cheng Yiping , Yu Wenhao , Zhou Yuping , Zhang Tao , Chi Haiyan , Xu Chao
Published: January 2022

The role of inflammation has been identified in the pathogenesis of diabetic ketoacidosis (DKA). The neutrophil/lymphocyte ratio (NLR) and white blood cells (WBC) can be used to predict a systemic inflammatory response. Changes in NLR and WBC levels have never been explored in type 1 diabetes mellitus (T1DM) patients with DKA and an uninfected state. This retrospective study included a total of 644 participants. NLR and WBC were measured in the control group (n = 316) and in T1DM patients with mild-DKA (n = 92), severe-DKA (n = 52), and non-DKA (n = 184) in an uninfected state. Then, we assessed the independent predictors of DKA occurrence in T1DM patients in an uninfected state. The diagnostic performance of variables was determined by receiver operating characteristic curve analysis. Serum NLR of T1DM patients is significantly higher than that of normal controls, and if DKA occurs, NLR increases further and increases with the severity of DKA. In addition to diastolic blood pressure, blood urea nitrogen, glycated hemoglobin (HbA1c), and WBC, NLR was also independently associated with DKA in T1DM patients with an uninfected state (OR = 1.386, 95% CI: 1.127–1.705, p = 0.002). Furthermore, the diagnosis analysis showed that except for NLR and WBC, the area under the curve (AUC) of indicators with a statistical difference in patients with and without DKA were 0.747 for DKA diagnosis, and after the addition of NLR and WBC, the AUC was 0.806. The increased NLR level represents a low-cost and highly accessible predictor for DKA in T1DM patients with an uninfected state. The addition of inflammation indicators can play a statistically significant role in the prediction model of the DKA occurrence.
Nursing students’ experiences and perceptions of an innovative graduate level healthcare grand challenge course: a qualitative study
Authors: Nowell Lorelli , Dhingra Swati , Carless Sandra , Davidson Sandra , Carr Eloise
Published: January 2022

Nursing leaders are increasingly required to create and implement innovative solutions to address challenges in the workplace. However, the present-day education of graduate nurses may not adequately prepare them for entrepreneurial approaches to problem solving required in today’s complex healthcare environments. To fill this gap, we designed, implemented, and evaluated a Healthcare Grand Challenge course for graduate nurses interested in developing their leadership skills. Following the course, students were invited to participate in a qualitative research study to explore their experiences and perceptions of the course and identify how they used the knowledge and skills developed through the course in their leadership practices. This study provides key lessons for future offerings of grand challenge courses while highlighting the influence of grand challenge courses on current and future nursing leadership practice.
The Invention of Clutter and the New Spiritual Discipline of Decluttering
Authors: Lang Hearlson Christy
Published: January 2022

This essay argues that the popular global decluttering movement epitomized in Marie Kondo is a new spiritual discipline tailored to a particular cultural moment in which members of affluent societies, especially women, are caught between the shame of displaying too much “stuff” at home and the guilt of discarding it. After suggesting reasons for the movement’s neglect by theologians, the essay offers a brief history of the “invention of clutter.” Through this history, the essay frames decluttering as an expression of “makeover culture” that posits a timeless aesthetic self. Decluttering functions as a spiritual practice of late consumer capitalism that converts its followers to a disposition of detachment through procedures that mirror Christian conversion. While appreciating the attention the movement shows to women’s domestic lives and to material things, the essay offers a theological critique of the movement’s construction of an aesthetic self who is absolved of guilt by escaping time and the ecological web into private, timeless space. The essay commends instead a narrative, ecological self whose engagement with material things reflects a sacramental vision that issues in virtues like frugality.
Compact meta-spectral image sensor for mobile applications
Authors: Lee Jaesoong , Park Yeonsang , Kim Hyochul , Yoon Young-Zoon , Ko Woong , Bae Kideock , Lee Jeong-Yub , Choo Hyuck , Roh Young-Geun
Published: January 2022

We have demonstrated a compact and efficient metasurface-based spectral imager for use in the near-infrared range. The spectral imager was created by fabricating dielectric multilayer filters directly on top of the CMOS image sensor. The transmission wavelength for each spectral channel was selected by embedding a Si nanopost array of appropriate dimensions within the multilayers on the corresponding pixels, and this greatly simplified the fabrication process by avoiding the variation of the multilayer-film thicknesses. The meta-spectral imager shows high efficiency and excellent spectral resolution up to 2.0 nm in the near-infrared region. Using the spectral imager, we were able to measure the broad spectra of LED emission and obtain hyperspectral images from wavelength-mixed images. This approach provides ease of fabrication, miniaturization, low crosstalk, high spectral resolution, and high transmission. Our findings can potentially be used in integrating a compact spectral imager in smartphones for diverse applications.
Fabrication of inverted organic solar cells on stainless steel substrate with electrodeposited and spin coated ZnO buffer layers
Authors: Namawardana D. G. K. Kalara , Wanigasekara R. M. Geethanjana , Wanninayake W. T. M. Aruna P. K. , Jayathilaka K. M. D. Charith , Wijesundera Ruwan P. , Siripala Withana , Malik Muhammad Imran
Published: January 2022

Polymer based organic solar cells (OSCs) are of tremendous interest as suitable candidates for producing clean and renewable energy in recent years. In this study, inverted OSCs on stainless steel (SS) substrate with zinc oxide (ZnO) as the electron selective transport layer (ESTL), are investigated, occupying bulk heterojunction blend of regioregular poly(3-hexylthiophene) (P3HT) and phenyl-C61-butyric acid methyl ester (PCBM) as the active material and poly-(4,3-ethylene dioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) as the hole transport layer (HTL). The device structure is SS/ZnO/P3HT:PCBM/PEDOT:PSS/Au. ZnO films are prepared by spin coating and electrodeposition techniques, followed by annealing under ambient conditions. The insertion of ZnO layer between the SS substrate and active layer has improved short-circuit current (J
sc), open-circuit voltage (V
oc), fill factor (FF), and power conversion efficiency (PCE) compared to those of the reference cell without ZnO layer, achieving the highest efficiency of 0.66% for the device with spin coated ZnO from sol–gel technique. This enhancement can be attributed to the effective electron extraction and the increased crystallinity of ZnO after annealing treatments at higher temperatures as further confirmed by X-ray diffraction (XRD) and scanning electron microscope (SEM) analyses.
Review of characteristics and analytical methods for determination of indomethacin
Authors: Dandić Andrea , Rajkovača Katarina , Jozanović Marija , Pukleš Iva , Széchenyi Aleksandar , Budetić Mateja , Samardžić Mirela
Published: January 2022

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the first choice of treatment for rheumatic disorders and other degenerative inflammatory diseases. One of them, indomethacin (INDO), is highlighted in this study. With its analgesic, antipyretic, and anti-inflammatory properties, it is one of the most powerful drugs used in various clinical trials and therapies related to the mechanism of blocking prostaglandin synthesis, thus reducing and eliminating many inflammatory conditions in patients. To ensure the efficacy and safety of this drug in pharmaceutical and clinical use, precise product quality control is required. Such control is performed with routine pharmaceutical analysis using various chemical methods by which INDO is identified as a separate active ingredient in the multicomponent system of a complete pharmaceutical form. In addition, the determination of INDO is important in clinical practice, where its concentration is determined in different biological samples, ensuring better monitoring of a particular therapy. The most commonly used methods for the determination of INDO are high-performance liquid chromatography (37% of developed methods), voltammetry (16% of developed methods), and UV spectroscopy (11% of developed methods). However, each of these methods must provide precise validation parameters. A combination of analytical methods can lead to more precise results and safer application in practice.
Crystallographic complexity partition analysis
Authors: Hornfeck Wolfgang
Published: January 2022

We present an illustrative analysis of the complexity of a crystal structure based on the application of Shannon’s entropy formula in the form of Krivovichev’s complexity measures and extended according to the contributions of distinct discrete probability distributions derived from the atomic numbers and the Wyckoff multiplicities and arities of the atoms and sites constituting the crystal structure, respectively. The results of a full crystallographic complexity partition analysis for the intermetallic phase Mo3Al2C, a compound of intermediate structural complexity, are presented, with all calculations performed in detail. In addition, a partial analysis is discussed for the crystal structures of α- and β-quartz.
Validation of Panoramic Ultrasound Measurement of the Cross-Sectional Area of the Vastus Medialis
Authors: Minnehan Kaitlin S. , Dexter William W. , Holt Christina T. , Scharnetzki Liz , Alex James P. , Chin Kaitlyn E. , Kokmeyer Dirk J.
Published: January 2022

Minnehan, KS, Dexter, WW, Holt, CT, Scharnetzki, L, Alex, JP, Chin, KE, and Kokmeyer, DJ. Validation of panoramic ultrasound measurement of the cross-sectional area of the vastus medialis. J Strength Cond Res 37(1): 41–45, 2023—The cross-sectional area (CSA) of the vastus medialis (VM) is an independent predictor of important clinical outcomes in musculoskeletal conditions of the knee, such as pain and long-term function. Previous studies validated ultrasound (US) to measure larger muscles of the thigh, but this approach has limited accuracy in measuring smaller muscles, such as the VM. In this study, we aimed to validate panoramic US measurements of the CSA of the VM and compare the results with those from the gold standard of magnetic resonance imaging (MRI) (significance set p ≤ 0.05). In this retrospective, single-center study, we compared pairs of US and MRIs taken of 25 adults who participated in a 10-week study of non–weight-bearing activity at a National Aeronautics and Space Administration facility. Images were acquired from various locations on the right thigh at multiple time points. Two researchers independently analyzed the US and MRI pairs by outlining the intermuscular border of the VM in the most distal image. We found excellent agreement between the US and MRI measurements of the CSA of the VM analyzed by researcher 1 (interclass correlation coefficient [ICC]: 0.997) and researcher 2 (ICC: 0.980). We also found excellent agreement for interrater reliability for MRI (ICC: 0.988) and US (ICC: 0.982) and intrarater reliability for US for researcher 1 (ICC: 0.999) and researcher 2 (ICC: 0.996). Our findings demonstrate that US is a valid and reliable tool for measuring the CSA of the VM compared with MRI.
An Exemplar Frontal Plane Visual Kinematic Stimulus Elicits Sex-Specific Learned Behavior: An Exploratory Report
Authors: Hogg Jennifer A. , Riehm Christopher D. , Diekfuss Jed A. , Simon Janet E. , Acocello Shellie N. , Liang Yu , Wu Dalei , Myer Gregory D. , Wilkerson Gary B.
Published: January 2022

Hogg, JA, Riehm, CD, Diekfuss, JA, Simon, JE, Acocello, SN, Liang, Y, Wu, D, Myer, GD, and Wilkerson, GB. An exemplar frontal plane visual kinematic stimulus elicits sex-specific learned behavior: An exploratory report. J Strength Cond Res 36(3): 857–861, 2022—The purpose of this exploratory study was to determine if a visually delivered kinematic stimulus designed to promote injury-resistant biomechanics would induce sex-specific motor learning effects. Six female subjects and 6 male subjects participated in 2 consecutive day sessions in which they mimicked an avatar performing 5 sets of 8 repetitions of exemplar frontal plane mechanics during single-leg squats. Acute (∼10 minutes) and delayed (∼24 hours) transfer testing under single-task (single-leg balance) and dual-task conditions (single-leg balance plus cognitive task) were referenced to baseline measurements. Center of pressure (CoP) mean velocity (Vel), SD, and detrended fluctuation analysis (DFA) in the anterior posterior (AP) and medial-lateral (ML) directions were quantified, with dual-task costs defined as the percentage difference from single-task to dual-task. Separate 2 × 3 repeated-measures analysis of variance was conducted for each dual-task cost variable. Main effects and interactions with large effect sizes considered as

≥ 0.14 were further explored with pairwise post hoc comparisons. Sex by time interactions were observed for medial-lateral standard deviation cost (

= 0.29; p = 0.04), anterior-posterior standard deviation cost (

= 0.27; p = 0.06), and AP DFA cost (

= 0.41; p = 0.007), in which female subjects displayed lower dual task cost at acute transfer testing compared with male subjects (Cohen's d = 1.52, 1.64, 0.97; p = 0.03, 0.02, and 0.13 respectively). This report provides preliminary evidence that female subjects may be more responsive than male subjects to a prescribed frontal plane kinematic visual stimulus. Based on these sex-specific effects, future visually driven stimuli may require alternative strategies to optimize efficacy in male subjects.
Quantifying the impact of future extreme heat on the outdoor work sector in the United States
Authors: Licker Rachel , Dahl Kristina , Abatzoglou John T.
Published: January 2022

Outdoor workers perform critical societal functions, often despite higher-than-average on-the-job risks and below-average pay. Climate change is expected to increase the frequency of days when it is too hot to safely work outdoors, compounding risks to workers and placing new stressors on the personal, local, state, and federal economies that depend on them. After quantifying the number of outdoor workers in the contiguous United States and their median earnings, we couple heat-based work reduction recommendations from the U.S. Centers for Disease Control and Prevention with an analysis of hourly weather station data to develop novel algorithms for calculating the annual number of unsafe workdays due to extreme heat. We apply these algorithms to projections of the frequency of extreme heat days to quantify the exposure of the outdoor workforce to extreme heat and the associated earnings at risk under different emissions scenarios and, for the first time, different adaptation measures. With a trajectory of modest greenhouse gas emissions reductions, outdoor worker exposure to extreme heat would triple that of the late 20th-century baseline by mid-century, and earnings at risk would reach an estimated $39.3 billion annually. By the late century with that same trajectory, exposure would increase four-fold compared to the baseline with an estimated $49.2 billion in annual earnings at risk. Losses are considerably higher with a limited-mitigation trajectory. While universal adoption of 2 specific adaptation measures in conjunction could reduce mid-century and late-century economic risks by roughly 90% and 93%, respectively, practical limitations to their adoption suggest that emissions mitigation policies will be critical for ensuring the well-being and livelihoods of outdoor workers in a warming climate.
Karpiowie z Karpowicz na Podlasiu w ostatniej ćwierci XVIII w. Zmierzch trzystuletniej historii
Authors: Karp Sławomir
Published: January 2022

The article presents the figure of Antoni Karp (ca. 1747 – ante 12.03.1791) the owner of the Karpowicze estate in the Podlasie Province in the 18th century. The profiles of successive owners of this property were also outlined.
Wyzwania dla transformacji demokratycznej w Republice Białoruś. Wstępne wnioski z 2020 r.
Authors: Czachor Rafał
Published: January 2022

The unprecedented wave of protests against A. Lukashenko in 2020 raises questions about the prospect of democratization in Belarus. The article introduces the theoretical issues related to the transformation of political systems and refers to the case of Belarus. Based on the experience of transitology and the science of transformation of political systems so far, it has been indicated that the future democratic success of Belarus is not obvious.
Нарратив “Польской угрозы” Беларуси в российских пропагандистских СМИ (на примере Sputnik.by)
Authors: Польовий Тарас
Published: January 2022

On the example of the site Sputnik.by, we showed the main anti-Polish propaganda narratives. Analyzed the quantitative and qualitative indicators of the considered resource. Determined the ways, means and goals of presenting the main theses of pro-Russian propaganda in Belarus. Noted that the rhetoric in this media intended to form a negative image of Poland in Belarus. Indicated that the use of the “Polish threat” narrative for Belarus is aimed at creating an image of an enemy in Belarusian society.
Odtwarzanie pamięci społecznej miasta na przykładzie grupy na Facebooku poświęconej przeszłości miasta Białystok
Authors: Wądołowski Wojciech
Published: January 2022

The article concerns the issue of recreating social memory on the example of visual materials posted on a popular Facebook profile entitled “Kronika Białostocka”. The collection of photographs was analyzed in terms of space, people and events that could create a picture of the past of the city and its inhabitants.
Диариуш Афанасия Филипповича и Житие протопопа Аввакума: типологические схождения в историческом контексте
Authors:   Uniwersytet w Białymstoku, Twaranowicz Halina
Published: January 2022

A leading position in the 17th century Belarusian literature is occupied by Afanasij Filipovich, a writer and publicist, a political and Orthodox Church activist. His “Diariuš”, an autobiographical work is one of the most distinctive examples of polemic publicity devoted to the fight against the Brest Union in 1596 and its tragic consequences. Meanwhile, a special place in the 17th century Russian literature is occupied by protopop Avvakum’s “Žitie” – a remarkable first apostle and a symbol of the Old Believers movement whose life experience served as the first autobiography in Russian literature. Afanasij Filipovich’s “Diariuš” and protopop Avvakum’s “Žitie” present sufficient grounds for considering various typological similarities and parallels in authors’ fate and the pathos of their works. New principles of the selfawareness of an individual and the ways of expressing them are present in the works of Belarusian and Russian writers.
Речевой комизм одностиший Владимира Вишневского
Authors:   Uniwersytet Marii Curie-Skłodowskiej, Iakovleva Olga
Published: January 2022

Linguistic comedy is a special case of the implementation of a language game. The aim of the paper is to identify the most frequent, periodic realized linguistic ways of creating a comic effect in V. Vishnevskii’s one-line poems. The study is based on such methods as: the descriptive method, the dictionary definition analysis method and the component analysis method. The results of the research reveal that among the ways of creating the discussed effect used in V. Vishnevskii’s one-line-poems, the following are distinguished: polysemy, antonymy, metonymy, violation of lexical connectivity of words, the author’s neologisms, ellipse, transformation of precedent texts, verbal-graphic representation, and combination of lexical units referring to various aspects of their use, characterized by different functional and expressive connotations.
Wpływy obce w tekstach czasopism luksusowych w języku rosyjskim, polskim i hiszpańskim (na przykładzie Cosmopolitan)
Authors:   Uniwersytet w Białymstoku, Romanik Anna
Published: January 2022

The focus of this paper is the impact of English observed in the language of an international magazine Cosmopolitan. The research was conducted taking into account three language versions of the monthly magazine: Russian, Polish and Spanish. Factual material was excerpted from the periodicals published in 2017–2021. Taking up this topic stems from the need to fill the gap in research on the language of luxury magazines, which have a great influence on forming the canons of linguistic norms and the linguistic awareness of their readers. The aim of the study is to analyze the collected Anglicisms (mainly loanwoard) in terms of their function, way of adaptation and presentation in the text space. Determining the reasons for the popularity of foreign forms in a given language space is also an important point of analysis. An additional assumption of the publication is to indicate the connections between the use of borrowings and the ideological concept of the magazine with cosmopolitanism.
LC-MS/MS profiling, antibiofilm, antimicrobial and bacterial growth kinetic studies of Pluchea dioscoridis extracts
Authors: El-Shazly Maha A.M. , Hamed Ahmed A. , Kabary Hoda A. , Ghareeb Mosad A.
Published: January 2022

The therapeutical applications of ornamental plants have been categorized to be of a great effectiveness in multiple industries from ancient times until present days. Pluchea dioscoridis is widely known Egyptian wooden plant that has been extensively applied for different medicinal purposes. In this study, LC-ESI-MS/MS analysis of the potent antimicrobial ethyl acetate and n-butanol extracts of P. dioscoridis leaves led to identification of 28 and 21 compounds, respectively. The identified compounds were categorized as phenolic acids, phenolic acids derivatives, organic acids, flavonoids (aglycones and glycosides), secoiridoids, coumarin derivatives, and gallotannins derivatives. Among them, caffeic acid 3-sulfate was the most predominate in the investigated extracts followed by ferulic acid and dicaffeoyl-quinic acid. Also, the antimicrobial potentiality of different extracts was evaluated against different pathogenic microbes including Enterobacter cloacae, Micrococcus leutus, Aeromonas hydrophila, Bacillus subtilis, Bacillus cereus, Bacillus lichneformis and Clostridium species. Furthermore, different concentrations of the most potent extract were assayed for antibacterial efficacy on growth curve kinetics against the susceptible bacteria along 4days incubation period. Our gathered data confirmed that, the antimicrobial activity against tested bacteria was different according to the solvent used in the extraction process. Mostly, all the extracts showed a wide spectrum antibacterial activity except the plant water extract which shows a mild activity against Clostridium sp. only. Based on the highest inhibition zone diameter, the ethyl acetate extract followed by butanol extract exhibited the highest inhibition zone with Micrococcus luteus and B. subtilis (20.0 and 18.5 mm) respectively. Determining the effect of ethyl acetate extract at different concentration (0, 0.66, 1.66, 3.33, 6.67, 13.34 and 20.01 mg mL−1) on M. luteus growth kinetics, the data assured that the antibacterial activity shows concentration dependent manner with the highest antibacterial activity at 20.01 mg mL−1 culture. The data also confirmed that, none of the selected concentration showed bactericidal activity in the prepared cultures, and with the prolonged incubation period the bacteria acquire resistance against the extract beginning from second or third day of incubation.
Indicators of vitamin D in case of Coronavirus infection COVID-19 in children
Authors:   Azerbaijan Medical University, Baku, Hasanov A.G. , Huseinova I.E. ,   Azerbaijan Medical University, Baku
Published: January 2022

Purpose — to determine and compare vitamin D levels in children diagnosed with COVID-19-associated pneumonia and healthy children. Materials and methods. The study involved 90 children. The main group consisted of 75 inpatient children with a diagnosis of COVID-19-associated pneumonia (positive PCR — polymerase chain reaction with reverse transcription). Patients in the main group were divided into 2 subgroups: subgroup I consisted of 49 patients with a pneumonia of moderate course, and subgroup II — 26 patients with a pneumonia of severe course. The control group consisted of 15 practically healthy children. The scheme of examination of sick children included anamnestic data, the use of clinical, instrumental and laboratory, immunological examination methods. The concentration of vitamin D in the blood serum of sick and healthy children was determined by the method of enzyme3linked immunosorbent assay (ELISA). The indicators were measured on a Stat Fax 4700 device using a Pishqaman reactive kit (made in Germany). Results. The concentration of vitamin D in blood serum was 1.8 times lower in subgroup I and 2.0 times in subgroup II, compared with the control group. The average values of vitamin D in blood serum compared with the control group were <1.1 times lower in the age group <1 year, 1.1 times lower in the age group 1–3 years, and 2.3 times lower in the age group >3 years. Conclusions. Based on our research, it can be concluded that there is a relationship between vitamin D deficiency and COVID-19. Thus, the average level of vitamin D was lower in children with COVID-19-associated pneumonia, and varied depending on the severity of the disease (more pronounced changes were observed in severe pneumonia). There are also differences in vitamin D levels in the age groups of children with COVID-19-associated pneumonia: in children from age groups under 1 year and 1–3 years old the decrease in serum vitamin D level is less pronounced than in the age group over 3 years old. The main mechanisms of vitamin D involvement in the immune modulation process in COVID-19 require further study. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local ethics committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: children, COVID-19, vitamin D.
Influence of vitamin D provision on the course of acute respiratory infections in children
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Marushko Yu.V. , Esipova S.I. ,   Bogomolets National Medical University, Kyiv, Ukraine, Gishchak T.V. ,   Bogomolets National Medical University, Kyiv, Ukraine,
Published: January 2022

The review article provides data from modern studies confirming the multifaceted effect of vitamin D in the human body. Vitamin D3 receptors (VDRs) have been shown to be present in most organs and tissues of the body. This confirms the importance of vitamin D not only in the formation of the skeletal system, but also in many of its extraosseous effects. Calcitriol affects the modulation of cell growth, neuromuscular conduction, inflammation processes, and is also an important stimulator of innate immunity due to the synthesis of antimicrobial peptides that provide protection against bacteria and viruses. In recent years, the relationship between the concentration of vitamin D in the blood and the incidence of respiratory infections in children has been actively studied. Many studies have shown that low vitamin D status is characteristic of most children with respiratory infections, and an adequate level of 25(OH)D in serum has a positive effect on the frequency of these infections and the severity of their course. Most authors demonstrate the benefits of vitamin D supplementation in the prevention of respiratory diseases in children, but there is no consensus regarding the frequency and dosage of vitamin D. The authors declare that they have no conflicts of interest. Key words: vitamin D, children, deficiency, respiratory diseases, prevention.
Playing to be influencers: A comparative study on Spanish and Colombian young people on Instagram
Authors: Caro-Castaño Lucía
Published: January 2022

This paper explores and describes how Colombian and Spanish young people present themselves on Instagram according to the social game and the symbolic capital that they infer as normative from influencers. The methodology used combines the focus group technique (seven groups) with a content analysis of the profiles of the informants (N = 651). In total, 53 first-year creative industries university students participated. The results show that the work developed by the influencers has given rise to an aspirational narrative genre that young people tend to emulate according to the Instagram habitus in order to be recognised as leading players. Their self-presentation has three main features: a) a preference for showing ‘in-classifying’ practices such as leisure and tastes for freedom; b) the predominance of a specific type of profile and gestures that avoids self-production markers and aspires towards a global audience; and c) the normalisation of self-promotional discourse. Most informants experience Instagram as a game in which they compete to accumulate visibility conceived as relational validation, although in the case of Colombian informants there is a more professional outlook towards the platform. Finally, for all of them, Instagram constitutes a serious game, and many of them admit to feeling too exposed. As a result, they have implemented self-surveillance practices, such as consulting with peers before posting photographs, using secondary accounts and deleting posts.