bluuebunny/crossref_metadata_2025 huggingface dataset:
PEMBERDAYAAN MASYARAKAT DESA KUTAMBARU MENUJU DESA ECO AGRO TOURISM
Authors: Nasution Lita , Ranita Sylvia Vianty , Afandi Ahmad , Ginting Makhrani Sari , Barus Wan Rose Pinkutri
Published: August 2024

Agrowisata, kombinasi dari pertanian dan pariwisata, berperan penting dalam meningkatkan pendapatan dan kesejahteraan masyarakat pedesaan melalui pemanfaatan sektor pertanian sebagai objek wisata. Di Daerah Istimewa Yogyakarta, terdapat berbagai spot agrowisata menarik, seperti agrowisata Salak Pondoh di Sleman, yang menawarkan berbagai fasilitas dan kegiatan rekreasi. Desa Polengan dan Desa Kembangarum juga menunjukkan potensi besar dalam pengembangan desa wisata berbasis pertanian dan potensi alam. Namun, tantangan seperti daya tarik yang kurang dan kondisi yang kurang terawat menghambat pertumbuhan agrowisata. Oleh karena itu, strategi pengembangan yang melibatkan masyarakat dan optimalisasi sumber daya lingkungan sangat penting. Selain itu, penggunaan metode pemrograman linier dapat membantu mengoptimalkan produksi dan profitabilitas usaha pertanian. Pandemi COVID-19 telah menguji ketahanan ekonomi, namun modal sosial menjadi kunci untuk mengatasi tantangan ini dan mendorong pertumbuhan ekonomi. Contoh sukses adalah Desa Pujon Kidul di Malang yang telah meningkatkan PADes melalui pariwisata desa. Upaya konservasi lingkungan, pengelolaan sampah yang cerdas, dan teknologi pertanian modern juga menjadi faktor penting dalam pengembangan agrowisata yang berkelanjutan. Desa Kutambaru di Sumatera Utara menunjukkan bahwa pemberdayaan masyarakat dan kerjasama dengan berbagai pihak dapat menciptakan desa eco agro tourism yang menarik wisatawan dan memberikan manfaat jangka panjang bagi masyarakat.
Improving the Nutritional Status of Stunted Toddlers by Utilizing Local Food in Coastal Labu Beach, Deli Serdang Regency
Authors: Nurandini Nabilah , Indirawati Sri Malem , Putri Najwa Azlisna , Siregar Hijriyatun Alhikmah
Published: August 2024

Pantai Labu sub-district is one of the sub-districts located on the coast but has a high number of stunting cases, stunting cases in Paluh Sibaji village are 5 toddlers. Health problems in Paluh Sibaji village have stunting cases that are very concerning even though it has marine potential with protein sources from fish. The village has a variety of abundant fisheries and marine resources. Local food diversity has the potential to be utilised as a source of cheap and easily available nutrition. The village has an abundant variety of fisheries and marine resources. The existence of tamban fish as a local food product has a low selling price and is underutilised as a source of animal protein. This community service aims to utilise local food ingredients as a source of protein for the community. The methods used are atmosphere building, socialisation, community empowerment and the formation of family groups concerned about stunting. This community service activity produced two local food innovations, namely characterised spinach tamban fish balls and moringa leaf tamban fish sticks. Both products are processed from cheap and easily available local raw materials in the village, namely tamban fish and moringa leaves.
Entrepreneurial dynamics in the information age: A systematic literature review of research patterns and intellectual structures (2005–2024)
Authors: Wang Jingjing , Wan Hussain Wan Mohd Hirwani Bin
Published: August 2024

This systematic literature review examines the convergence of entrepreneurship and information technology between 2005 and 2024. It investigates how the emergence of information technologies such as social networks, smart devices, big data, and cloud computing have transformed business operations and entrepreneurial approaches. The study use technologies such as Bibliometrix to analyze academic literature and identify research trends, knowledge structures, and their evolutionary routes. During the specified time frame, a grand total of 292 articles were published by 777 writers. These publications have played a key role in redirecting academic focus from traditional entrepreneurship to the field of digital entrepreneurship and the applications of information technology. A thematic analysis uncovers a shift from theoretical investigation to practical implementations and multidisciplinary research, while a co-citation analysis highlights important contributors and influential works. This study emphasizes the crucial importance of information technology in influencing entrepreneurial behaviors and strategic business decisions. It also offers valuable insights for future research and entrepreneurial practice in the information age.
Expression in Josef Matthias Hauer’s piano music as exemplified by Klavierstücke mit Überschriften nach Worten von Friedrich Hölderlin Op. 25
Authors: Barwinek Bartłomiej
Published: August 2024

Austrian composer Josef Matthias Hauer (1883–1959) went down in history as one of the leading figures of atonal music in the first half of the 20th century and the creator of an original—different from Schönberg’s—conception of twelve--tone technique. Although the principles of dodecaphony developed by the author of Nomos Op. 19 differ significantly from those established by the founder of the Second Viennese School, the most striking thing for the listener is the difference in the expressive sphere that occurs between pieces of both composers.

Fundamental to the issues of Hauer’s form and characteristic poetics is his aesthetic world view, which sets as the goal of his artistic work the idea of spiritual perfection, inspired among others by an esoteric interpretation of Johann Wolfgang Goethe’s beliefs.

The Klavierstücke Op. 25 discussed in this article allows—at least in part—for a more careful reading of this peculiar philosophy, thanks to a guide suggested by the composer himself, namely the poetry of Friedrich Hölderlin (1770–1843). Through the prism of its short fragments, which constitute the mottoes of the fourteen piano miniatures, we can come closer to justifying and explaining the expressive categories adopted by the composer.

The author analyses the expressive sphere of the work, considering its individual elements within three successive layers of expression: 1) an external one— reflected in the notational convention of the work, 2) an indirect one—concerning the historical and stylistic context, and 3) an internal one—encompassing the space of meaning and narration.
Mahler and the Taking Back of the Ninth
Authors: Berger Karol
Published: August 2024

The last word of Mahler’s Fifth Symphony, composed in 1901–02 and premiered in 1904, is ironic, mocking even, certainly not pompously triumphant. What is mocked here is the whole tradition of victorious symphonic scenarios epitomized by Beethoven’s Ninth Symphony, the “per aspera ad astra” tradition that had symphonists propose stories of suffering triumphantly overcome. The Finale also puts into question Mahler’s own past. For the first time, the composer writes here a symphony that does not aim at a transcendence and sublimity, but accepts the comic immanence of the earthly existence. The aspiration to transcendence fails, but is not forgotten, and neither are the negative aspects of human existence that gave rise to this aspiration
Four musical settings of the poem “In Danzig” by Joseph Eichendorff — music and the expression of the word
Authors: Schiller-Rydzewska Joanna
Published: August 2024

The poem In Danzig by Joseph Eichendorff, which appeared in the second edition of his works collected in 1848, is one of the most famous and important poems of the 19th century about Gdańsk. Its author, an important German poet of the Romantic era, has visited Gdańsk three times. From 1821 to 1824 he lived and worked here for the first time as a Prussian civil servant. In 1838, he spent several weeks in Gdańsk with his eldest daughter. The last time he spent in the city was in the years 1843–47 and lived with his family on Chlebnicka Street. At that time a poem was probably written in 1843 with the original title Nachts, later changed to Nachts in Danzig, finally entitled In Danzig.

This outstanding example of German romantic poetry proved to be an important source of inspiration for the work of composers of different formats. The most well-known example of the song based on the poem comes from the work of Hans Pfitzner, the German composer of the turn of XIX/XX. I also noticed two other works on the Eichendorff text by lesser-known composers during the inquiry in the Gdańsk Library: Max Stange and Alfred Balfanz. The latter was Gdańsks citizen. The immediate impetus for dealing with this problem was the work of the young composer Kamil Cieślik with the eponymous title, which was premiered by the Gdańsk Vocal Ensemble Art’n’Voices.

The object of the proposed reflection is therefore an attempt to compare the characteristics of the musical layer of the four works with regard to the expression of the poetic layer of Eichendorff’s poem. The thesis, which emerges in the initial stage of observation, follows intuition: the clarifications of the poem acquire a universal form to a certain extent. This means that the expression of the word in the works depicted is of utmost importance for the music.
Applied Research on the Evaluation of the Management System of a Welded Structure Manufacturing
Authors: Valentin Pîrvu , Corneliu Rontescu , Ana-Maria Bogatu , Dumitru-Titi Cicic
Published: August 2024

The implementation of a management system has increasingly become a necessity for organizations, one of the main purposes being to establish actions to achieve quality objectives. Currently there are many management systems but for a manufacturer of welded structures, in addition to the quality management system according to EN ISO 9001:2015 it is recommended to implement EN ISO 3834-2:2021 “Quality requirements for fusion welding of metallic materials. Part 2: Comprehensive quality requirements” The paper presents applied research on the assessment of the management system of a welded structure manufacturing organisation by conducting two internal audits at 7-month intervals as well as the analysis of the evolution of the management system after the implementation of corrective measures established after the first audit performed.
Public Debt and Economic Growth in Nigeria: A Consideration of New Evidence
Authors: Onyenwife Kingsley C. , Ezeanyeji Clement I. , Ekesiobi Chukwunonso
Published: August 2024

The discussion surrounding the connection between public borrowing and economic expansion has persistently endured without abating. While debt desirability proponents argue that public debt is growth-enhancing, others argue that public debt does more harm than good to the economy. In recent times, the increase in public debt in Nigeria continues to raise concerns regarding its desirability. Although several studies have been carried out in this regard, there is hardly any study that examines the public debt-growth nexus in the context of the tradable and non-tradable sectors. Second, there is hardly any study that disaggregates bank-sourced debt from non-bank-sourced debt. Thus, the study aimed to achieve two-pronged research objectives: To appraise the implications of public debt on the economic growth in the tradable sector of the Nigerian economy and to analyze the effect of public debt on the economic growth in Nigeria’s nontradable sector. This study spans from 1981 to 2020. Using the Generalized Linear Model (GLM), the following conclusions are made. Initially, different elements of public debt have varying impacts on the growth of the tradeable sector. External debt and debt obtained from non-bank sources positively drive the growth of the tradable sector. However, debt acquired from banks and the associated servicing costs hurt the growth of the tradeable sector. Furthermore, the different components of public debt have varying impacts on the growth of the non-tradable sector. Specifically, foreign debt and debt obtained from non-bank sources have a significant positive influence on the growth of the non-tradable sector. The influence of debt acquired from banks on the nontradable sector is positive but insignificant. However, similar to the tradable sector, the servicing of debt undermines the growth of the non-tradable sector. Policy insights were provided in line with the study’s findings.
A Novel Assessment of the Growth-Inequality Nexus in East-Central Europe
Authors: Pop Teodora M.
Published: August 2024

Abstrac

This paper investigates the nexus between economic growth and income inequality by exploring a sample of 11 Central and Eastern European (CEE) emerging countries from 2000 to 2019. The existing theory argues for three different situations that may appear: a positive link between economic growth and inequality, a negative association or a non-linear relationship. Generally, by employing a fixed-effects model that is robust to heteroskedasticity, cross-sectional dependence and autocorrelation, our findings reveal a significant non-linear growth-inequality connection, in accordance with Kuznets inverted U-shaped hypothesis. Additionally, we find that several transmission channels considerably influence this relationship in the CEE group, including poverty, educational attainment and trade openness. Our results denote a positive impact of international trade and human capital investment on reducing income inequality, emphasizing that an increase in the share of the population with tertiary education and trade openness will lead to a decrease in the Gini coefficient. Moreover, by improving the correlation between labour market requirements and the educational attainment of the population and adopting efficient poverty-reduction strategies, sustainable economic growth may mitigate the adverse influence of inequality in the long term. Therefore, policymakers should pay attention not only to the general macroeconomic framework of these countries but also to the implications of the socioeconomic dimension of inequality to reduce existing income disparities.
Decoding the Business Model: A Comparative Analysis with Strategy and Planning, and a New Seven-Keys Framework to Formulate A Business Idea
Authors: Todorova Ana , Pavlov Daniel
Published: August 2024

The article studies business models and their essence, comparing them to business plans and strategies. Various definitions and characteristics of business models are examined to be better understood and applied, both from a theoretical and a practical point of view. The aim is not to deny existing theoretical positions regarding business models but to suggest a new perspective where it is permissible, adapt existing knowledge to new business realities and opportunities and present an effective process for developing a business model. Through an in-depth content analysis of articles and reports published in renowned journals and conferences, multiple definitions of different researchers are given, and weaknesses in the interpretations are sought, but without challenging the existing paradigms. The systematic literature review found that the business model is applied with a much higher priority in practice than the business plan and strategy and enjoys significant interest from researchers. A major credit for this is its comprehensiveness in describing the design, structure and management of creating value by exploiting business opportunities. Our findings show that in academic and business circles, there is no clear enough distinction between business model, business plan and business strategy. Based on these findings, we present theoretical and applied guidelines and an innovative seven-keys framework for elaborating a business model.
INOVATIVNI PRISTUP U RAZVOJU SOCIJALNOG PREDUZETNIŠTVA
Authors: Niškanović Nataša
Published: August 2024

Ovaj rad istražuje ulogu inovacija i prakse organizacija civilnog sektora u Srbiji u razvoju socijalnog preduzetništva, koristeći studiju slučaja Feminističkog kulturnog centra BeFem. Rad obuhvata teorijski okvir, analizu studije slučaja i zaključne razmatranja o uticaju ovih organizacija na razvoj socijalnog preduzetništva.
MERENJE KORISNIČKOG ISKUSTVA U FUNKCIJI BREND MENADŽMENTA
Authors: Lukić Nataša
Published: August 2024

U ovom radu će biti predstavljeno koli­ko je važno da se kompanije orijentišu na kupce i izgrad­nju dugoročnih odnosa sa njima. Teorijski deo se bavi pojmovnim odrednicama brenda, upravljanjem odnosima sa kupcima i pristupom orijentisanom na kupce. U empi­rijiskom delu će biti predstavljen metod merenja zado­voljstva poslovnih kupaca u cilju praćenja i unapređenja korisničkog iskustva.
UNAPREĐENJE PROCESA TRANSPORTA I SKLADIŠTENJA U PREDUZEĆU „VEKAMP KOMERC”
Authors: Savić Katarina
Published: August 2024

U radu je prikazana analiza literature i teorijske postavke za proces transporta i skladištenja, a zatim praktično na primeru preduzeća „Vekamp komerc”. Metoda koje je korišćene za analizu je ishikawa a nakon analize su predložene mere unapređenja koje će poboljšati procese, doprineti kvalitetu poslovanja, efikasnosti u vršenju istih i doneti uštedu u vremenu i resursima.
UNAPREĐENJE PROCESA POSLOVNE KOMUNIKACIJE U TRANSPORTNOJ INDUSTRIJI
Authors: Radaković Dušanka
Published: August 2024

U radu se kroz teorijski deo opisuju značaj komunikacije i osnovne vrste, kao i komunikacioni modeli. U praktičnom delu rada je izvršena detaljna analiza interne i eksterne komunikacije u preduzeću koje posluje u transportnoj industriji. Na kraju praktičnog dela dati su predlozi za unapređenje interne i eksterne komunikacije.
ПРОЈЕКТОВАЊЕ И ИЗРАДА ПРОТОТИПА ЛАСЕРСКЕ МАШИНЕ ЗА ГРАВИРАЊЕ И СЕЧЕЊЕ
Authors: Ћирић Мирна
Published: August 2024

Рад се састоји из две целине –пројектовање CNC машине и израда и тестирање прототипа. Прво ће бити дат увод у CNC машине, затим пројектовање машине према захтеваним условима што обухвата избор компоненти и израду управљачког програма за микроконтролер. Tакође, биће приказана израда и тестирање рада прототипа CNC машине за гравирање и сечење ласером.
PRIMENA ALGORITMA OBRADE ZVUKA ZA OTKRIVANJE ANOMALIJA U RADU ELEKTROMOTORA U KONTEKSTU PREDIKTIVNOG ODRŽAVANJA
Authors: Kovjanić Nikola
Published: August 2024

Ovaj rad opisuje analizu konceptu­alnog rešenja sistema za ranu detekciju kvara mašine, baziranog na metodi zvučne detekcije anomalija.
UPOREDNA ANALIZA REALNIH I SINTETIČKIH RADARGRAMA ZA SLUČAJ SLOŽENIH SCENARIJA
Authors: Cvetinović Jovana
Published: August 2024

U ovom radu je prikazan kompletan proces obrade i analize realnih radargrama detektovanih na terenu, korišćenjem tehnologije skeniranja georada­rom, primenom tri antene različitih frekvencija (200MHz, 400MHz i 900MHz), na osnovu kojih su se generisali sintetički radargrami u softverskom paketu GprMax kao i uporedna analiza generisanih sintetičkih i realnih radar­grama.
Expanding Participation in Hebrew Education: Lessons Learned from French Immersion
Authors: Barel Adi
Published: August 2024

This article explores ideas for innovating the field of Hebrew education (HE) in non-Orthodox day schools in diaspora communities. It proposes strategies and identifies areas of further research to expand the reach of HE schooling to attract new families. These strategies were created through defining and exploring the Toronto HE landscape, and then comparing between HE and French Immersion (FI) programs in Ontario, where the performance and benefits of the latter are found to help inform meaningful reforms in the former. Interviews were subsequently conducted with affiliates of different schools within the FI system in Toronto. Jewish parents were asked about the factors that drew them to register their children in an FI program. Along with an FI teacher and principal, they were also asked to identify successes and challenges of FI practices. Finally, the paper discusses suggestions for future studies and offers ideas to help expand participation in HE and further strengthen the connection of diaspora communities to the Hebrew language.
Tratamento anti-inflamatório na depressão: uma revisão sistemática
Authors: Costa Braga Bárbara Dicarlo , Costa Bruna Teixeira da , Azevedo Katiene Rodrigues Menezes de
Published: August 2024

Introdução: A alta prevalência de depressão na população mundial, associada à elevada morbidade do transtorno, torna necessário o desenvolvimento de tratamentos eficazes. Estudos recentes comprovaram a correlação entre inflamação e desenvolvimento de quadros depressivos. Objetivos: Avaliar o uso de substâncias anti-inflamatórias no manejo de pacientes com depressão uni e bipolar. Metodologia: Este estudo é uma revisão sistemática com análise qualitativa baseada no protocolo Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A busca foi realizada na Biblioteca Virtual em Saúde e PubMed. Sete estudos foram selecionados. Resultados: O número de estudos que mostraram eficácia do celecoxibe e do infliximabe foi próximo daqueles que não o foram, os biomarcadores séricos foram relacionados à diminuição das escalas de depressão com ambos. Conclusões: Os resultados sobre a eficácia do tratamento anti-inflamatório na depressão ainda são inconclusivos devido à heterogeneidade das pesquisas e ao baixo número de estudos disponíveis.
Custo-efetividade do reparo da lesão do manguito rotador com âncoras knotless
Authors: San Junior Yonder Archanjo Ching , Silva Carlos Roberto Lyra da , Ramos Max Rogerio Freitas , Machado Daniel Aragão , Marta Cristiano Bertolossi , Peregrino Antônio Augusto de Freitas , Furtado Monique  de Sousa , Silva Roberto Carlos Lyra da
Published: August 2024

Objetivo: Avaliar se a cirurgia de reparo “equivalente trans-ósseo” do tendão supraespinal utilizando sistemas de âncoras sem nó é uma alternativa custo-efetiva no Sistema Único de Saúde. Métodos: A modelagem estática foi do tipo árvore de decisão. As estimativas de efetividade foram extraídas de uma coorte composta por trinta e oito pacientes submetidos a cirurgia do manguito rotador em um hospital público de referência em ortopedia que utilizaram âncoras sem nó e com nó. Os custos das intervenções foram estimados pela técnica de macrocusteio. O horizonte temporal foi de cento e doze dias e a perspectiva de análise foi a do Sistema Único de Saúde em nível local. Resultados: A razão de custo-efetividade incremental foi por funcionalidade articular e recuperada no valor de R$ 3.941,00. Conclusão: Os resultados do modelo sugerem que, dependendo da disposição de pagar do gestor, o reparo do manguito rotador utilizando âncoras sem nó pode ser uma alternativa mais custo-efetiva ao Sistema Único de Saúde ao invés do rotador com âncoras com nó.
Lenticular progressive myopia in a young male patient
Authors: Echieh Chigozie Ifeoma , Eldanasoury Mohammed Alaa
Published: August 2024

Cataracts often develop as part of the natural aging process. Nuclear sclerosis, a type of cataract causes the core of the lens to harden which ultimately increases the lens refractive power and causes nearsightedness. Although myopia is associated with nuclear sclerosis, this finding is not common among young individuals less than 40 years. The purpose of the study is to report a case of visual disabling nuclear cataract in a young myopic male who was previously diagnosed as being amblyopic in his left eye following visits to several physicians. A 35-year-old public service male worker presented to us with history of painless progressive diminution of vision in his left eye of five years duration. We performed a detailed ocular examination which showed an unaided distant vision right eye (RE)- 20/200; and the left eye (LE) - 20/400. His aided Vision (spectacles) RE: 20/20; LE: 20/160. An anterior segment examination using the slit lamp biomicroscope was normal except for the lens which showed nuclear sclerosis grade 1+ in the right eye and grade3+ in his left eye. The fundus examination was normal. A Swept Source Anterior Segment Optical Coherence Tomography (OCT) and Itrace ray tracing aberrometer assessed the density of the nucleus opacity and degree of internal aberrations induced by the nuclear sclerotic cataract respectively. He subsequently had a phacoemulsification surgery with an extended depth of focus non-toric intraocular lens implantation (EDOF-non-toric IOL) and attained a best corrected visual acuity (BCVA) of 20/20 in his left eye. Cataract extraction is therapeutic in young myopes with visually disabling nuclear sclerosis and prompt diagnosis is important to avoid repeated visits to the ophthalmologist.
Csendőrségi házkutatás egy kárpátaljai görögkatolikus kolostorban
Authors: Kosztyó Gyula
Published: August 2024

Ebben az írásban azt mutatjuk be, hogy miként zajlott 1939. március 23-án egy csendőrségi házkutatás a munkácsi görögkatolikus szerzetesrend kolostorában, közvetlenül a terület Magyarországhoz csatolását követően. Igyekszünk megállapítani a házkutatás indokát, miközben bemutatjuk, hogy a katonai közigazgatás idején milyen sztereotípiák uralkodtak a Bazil-renddel kapcsolatban. Ezen túl azt is megvizsgáljuk, hogy milyen kedvezőtlen külpolitikai hatása volt a házkutatásnak, miközben az eset belpolitikai következményeivel is foglalkozunk. Fontosnak tartjuk bemutatni, hogy milyen narratívát alkottak az eseményről a magyar karhatalom házkutatást végrehajtó tagjai, a szervezet vezetése és a helyi közigazgatás, illetve az azt elszenvedő szerzetesrend. Ezzel kapcsolatban rávilágítunk a különböző elbeszélések azonosságára csakúgy, mint az ellentmondásokra, miközben az egész történetet a magyar belpolitika kontextusába helyezzük.
Lúdas Matyi és a galambszárny : Talált tárgyak történetei
Authors: Unger Gabriella
Published: August 2024

Egy korábbi írásomban már foglalkoztam az állambiztonsági iratok egyfajta mellékleteivel, a dossziékhoz csatolt tárgyakkal.1 Most ezt a témát szeretném folytatni, hiszen az elmúlt években több olyan tárgy is előkerült, amelyek érdekesek lehetnek. Természetesen most sem elsősorban maguk az egyes tárgyak lényegesek, hanem azok a történetek, amelyekben szerepet játszhattak. A tárgyak némelyike vizsgálati eljárás, mások az állambiztonsági szervek operatív munkája során kerültek egy-egy dossziéba. Utóbbiak körébe tartoznak pl. a jeltárgyak, falfirkálásos ügyek technikai vizsgálatra küldött festékmintái, röpcédulázási ügyekhez kapcsolódó egyéb tárgyak vagy akár egy ellopott zacskó dohány.
Analysis of Feasibility Test Parameters for FTTH Access Networks with GPON Technology in the East Pontianak Perum 4 Area
Authors: Sentosa Adi , Tjahjamooniarsih Neilcy , Kusumawardhani Eka
Published: August 2024

This research employs Optisystem for evaluating network quality through calculation and simulation. It includes direct observation of installed devices at Perum 4 East Pontianak and network simulations using parameters like Power Link Budget, Rise Time Budget, BER, and Q factor. Calculations indicate that power levels on the downstream and upstream sides meet the standard. RTB analysis and BER and Q factor simulations confirm compliance with PT Panglima Kamayo Media and ITU-T G.984 standards. However, a design-implementation mismatch affects two consumers with significant power deviations, necessitating network improvements. PLB and RTB calculations on both sides confirm compliance with standards, and simulations validate the furthest network's feasibility. Yet, two specific consumers, 24 and 27, require improvements due to Prx power exceeding limits. These enhancements should consider internal and external factors, such as anthill interference. Overall, Perum 4 East Pontianak's FTTH network meets standards with potential improvements for uniformity, offering valuable guidance for PT Panglima Kamayo Media in enhancing consumer services.
Voltage Stability Index Improvement In Radial Distribution Systems Using Capacitors
Authors: Doni Donata , Gianto Rudy , Abidin Zainal
Published: August 2024

The radial distribution network system is an important part of the electric power system because this distribution system is useful for distributing electricity to loads (customers). the existence of voltage drops and electric power losses in the provision of electrical energy is something that cannot be avoided. There are several ways that can be done to improve voltage, one of which is the installation of Shunt capacitors in the primary distribution network. Voltage drop can occur in the power system due to the loss of voltage stability in the radial distribution network. This study analyzes the value of voltage stability index in 33-bus IEEE and 69-bus IEEE with current injection method power flow analysis. In the 33-bus IEEE system, the existing condition obtained the minimum bus voltage of 0.9131 pu or 11.560 kV occurs at bus-18. By installing 2 units of shunt capacitors in the 33-bus IEEE system, it can minimize active power losses from 202.464 kW to 157.153 kW or by 22.38%.  In the existing 69-bus IEEE system, the minimum bus voltage of 0.9092 pu or 11.511 kV occurs at bus-65. With the installation of 1 unit of shunt capacitor, the voltage at the installation of 3 units of shunt capacitors, the voltage at bus-65 is 0.9514 pu or 12.045 kV, which has increased by 0.534 kV. By installing 3 units of shunt capacitors in the 69-bus IEEE system, it can minimize active power losses from 224.698 kW to 22.994 kW or by 5.21%..
Understanding ligand exchange and surface passivation in CdS quantum dots from first principles
Authors: Frimpong Joseph , Aryal Sandip , Karun Tejas , Liu Zhen-Fei
Published: August 2024

The capping ligands on quantum dots (QDs) play a critical role in determining their stability and properties, making the ligand exchange process pivotal. However, rational design rules for selecting ligands to effectively passivate QD surfaces are lacking. In this study, we employ first-principles density functional theory and many-body perturbation theory to systematically examine how various ligands affect surface passivation and modulate the electronic and optical properties of QDs. We focus on the (111) and (100) facets of zinc blende CdS QDs and survey several common ligands: chlorine (-Cl), amine (-NH2), oleic acid [CH3(CH2)7CH=CH(CH2)7COOH], stearic acid [CH3(CH2)16COOH], and thioglycolic acid (HS-CH2-COOH). We elucidate the trends in surface passivation based on an electron counting argument. We discuss different effects associated with the ligand exchange, including the interface dipole, ligand binding mode, and many-body interaction. Our work provides structure-property relationships to pave the way for the rational design of effective QD ligands.
Perturbative spin-orbit couplings for the simulation of extended framework materials
Authors: Vogt Jan-Robert , Wilhelm Jan , Terraschke Huayna , Stock Norbert , Hehn Anna-Sophia
Published: August 2024

A comprehensive description of photo-chemical processes in materials, comprising spin-forbidden processes such as intersystem crossing and phosphorescence, implies to take into account spin-orbit coupling. We present an efficient implementation of a perturbative spin-orbit coupling correction for the Tamm-Dancoff approximation of linear-response time-dependent density functional theory within a mixed Gaussian and plane waves framework relying on spin-orbit coupling corrected pseudopotentials. The implementation is validated for a benchmark set of small aromatic molecules, with overall mean errors in excitation energies and spin-orbit coupling matrix elements being in the range of 0.1 - 0.6 eV and 1.0 to 13.6 cm−1 in comparison to density functional theory and density functional theory multi-reference configuration interaction reference results. Computational timings are given for a bismuth-containing metal-organic framework.
NPDBEjeCol: a natural products database from Colombia
Authors: Rodríguez-Pérez Johny Roberto , Valencia-Sanchez Hoover Albeiro , Mosquera-Martinez Oscar Marino , Gómez-García Alejandro , Medina-Franco Jose Luis , Cortes-Hernandez Hector Fabio
Published: August 2024

The analysis of chemical data sets represents a significant challenge for researchers due to the large quantity and dispersion of the data. In order to facilitate accessible recovery, it is necessary to organize the data into databases. The aim of this research is to compile and analyze information on natural products derived from plants in the Coffee region of Colombia through the online Natural Products DataBase EjeCol (NPDBEjeCol). It is the first database of its kind for the country. The workflow for the creation of the database began with the compilation of reported molecules of natural products derived from plants studied and present to the Coffee region of Colombia. This was achieved through a systematic literature review and dataset compilation conducted using the specified bibliometric equations, with a focus on articles published up to December 2023 and collecting information from research groups at Colombian universities. Once the set of molecules had been curated, molecular descriptors and fingerprints were calculated in order to evaluate the structural diversity and explore their chemical space in comparison with natural products reference libraries. The NPDBEjeCol database contains 236 molecules, for which detailed information is available. This includes the compound name, SMILES notation, references (journal name, DOI number, and year of publication), CAS number, synonym names, and constitutional descriptors. The database places an emphasis on small molecules with an average molecular weight of 234.77 g/mol and features a high structural diversity. The calculated physicochemical properties are in accordance with Lipinski's Rule of Five. Visualizations using PCA and t-SNE demonstrate the existence of distinct clusters of compounds and fragments, thereby highlighting the structural diversity. The compound database is publicly accessible via the web portal www.npdbejecol.com. The objective of the website is to facilitate open consultation, navigation, management, and visualization of the molecules identified through research on natural products derived from plants in the coffee region of Colombia.
HASANZ in 2024
Authors: Presland Bronwyn
Published: August 2024

This article provides a brief summary of the first decade of HASANZ.
Analysis of the Current Situation of “Internet Plus Nursing Service”
Authors: Zeng Xuemei
Published: August 2024

In the era of “Internet Plus,” technologies like big data, the Internet of Things, and cloud computing have revitalized nursing services in China, leading to the emergence of the “Internet Plus Nursing Services” model. This model facilitates on-site nursing care for discharged patients and special groups with mobility challenges, further advancing the construction of a Healthy China and enabling more people to access high-quality and continuous nursing services. Governments at all levels should actively improve the systems related to “Internet Plus Nursing Services” and simplify the appointment and operation processes. It is also essential to standardize the medical waste disposal process to ensure the quality of on-site nursing services, protect the legitimate rights and interests of both caregivers and patients and safeguard patient privacy and security. Additionally, building a robust “Internet Plus” platform to promote “online appointment of nurses” services, integrate nursing resources, and foster the healthy development of “Internet Plus Nursing Services” is crucial.
Effects of Melatonin on Spermatozoa Activity and Associated Mechanisms in Heat-Stressed Rats
Authors: Tan Kai , Chen Wenduo , Huang Jing , Pan Jianzhi
Published: August 2024

In animals, heat stress (HS) disrupts spermatogenesis, reducing sperm quality and, in severe cases, potentially inducing the loss of male reproductive function. Melatonin confers significant resistance to oxidative stress and apoptosis; however, its specific effects on rat spermatocytes and the mechanism underlying its anti-HS effects remain inadequately explored. Therefore, this study aimed to analyze the effects of melatonin at different concentrations on sperm cell activity in heat-stressed rats. Modeling heat stress injury, sperm viability and density assay, sperm plasma membrane integrity analysis, and oxidative stress assay of testicular tissue were conducted. The results revealed that HS caused sperm cell injury. However, the intraperitoneal injection of melatonin effectively improved spermatozoa quality, and a dose of 1 mM significantly alleviated the HS-induced damage. Moreover, HS increased the levels of oxidative and endoplasmic reticulum (ES) stress in rat testicular tissues, inducing germ cell apoptosis and pathological changes. Similarly, melatonin treatment improved sperm cell viability and density, inhibited germ cell apoptosis, and reduced oxidative and ES stress levels. Overall, melatonin effectively reduced the adverse effects of HS on rat sperm cells, and an intraperitoneal injection of 1 mM (0.6966 mg) melatonin facilitated the normal production of spermatozoa. Notably, its mechanism may involve reduced ES and oxidative stress levels in testicular tissues, increased expression of the anti-apoptotic protein Bcl-2, and inhibition of germ cell apoptosis.
A Study of the Causes of In-Hospital Mortality in Patients with Acute Myocardial Infarction Complicated by Gastrointestinal Haemorrhage
Authors: Chen Dalei
Published: August 2024

Objective: To analyze the risk factors for death during hospitalization in patients with acute myocardial infarction (AMI) complicated by gastrointestinal bleeding (GIB). Methods: 260 patients with AMI complicated by GIB who were admitted to the cardiology department of a hospital from January 2022 to December 2023 were retrospectively analyzed. 27 patients who died during hospitalization were designated as the control group and the 233 patients who survived as the observation group. Baseline data and clinical indexes of patients in the two groups were compared, and multifactorial logistic regression was applied to analyze the risk factors for death during hospitalization in patients with AMI complicated by GIB. Results: Univariate analysis showed that the control group had higher proportions of patients with Killip classification III to IV on admission, new arrhythmias, and mechanical complications, as well as higher heart rates, white blood cell counts, urea nitrogen, and creatinine levels. The proportion of patients who received transfusion therapy during hospitalization was also higher in the control group. Conversely, the control group had lower systolic and left ventricular ejection fraction rates compared to the observation group, with statistically significant differences (P < 0.05). Multifactorial logistic regression analysis revealed that new-onset arrhythmia (OR = 2.724, 95% CI 1.289–5.759), heart rate > 100 beats/min (OR = 3.824, 95% CI 1.472–9.927), left ventricular ejection fraction < 50% (OR = 1.884, 95% CI 0.893–3.968), BUN level (OR = 1.029, 95% CI 1.007–1.052), and blood transfusion (OR = 3.774, 95% CI 1.124–6.345) were independently associated with an increased risk of death during hospitalization in patients with AMI complicated by GIB. Conclusions: New arrhythmia, heart rate > 100 beats/min, left ventricular ejection fraction < 50%, elevated BUN levels, and blood transfusion are risk factors for death during hospitalization in patients with AMI complicated by GIB.
A Study on the Effect of Staged Enteral Nutrition Health Education on the Rehabilitation of Patients with Upper Gastrointestinal Bleeding
Authors: Chen Dalei
Published: August 2024

Objective: To analyze the influence of stage-specific enteral nutrition health education on the rehabilitation outcomes of patients with upper gastrointestinal bleeding (UGIB). Methods: A total of 120 patients with UGIB, treated between August 2021 and August 2023, were randomly divided into two groups: the observation group and the control group. The control group received standard enteral nutrition nursing intervention, while the observation group received an additional stage-specific enteral nutrition health education intervention based on the control group’s method. The intervention status of the two groups was then evaluated. Results: Before the intervention, the serum hemoglobin levels of the two groups were comparable (P > 0.05). After the intervention, the nutritional indicators in the observation group improved significantly and were higher than those in the control group (P < 0.05). Additionally, the observation group had shorter bed activity times and hospitalization periods, a lower rate of abandonment of nutritional preparations, and a higher quality of life compared to the control group (P < 0.05). Conclusion: The implementation of stage-specific enteral nutrition health education in the treatment of patients with UGIB helps accelerate the rate of recovery, improve nutritional indexes, and enhance the quality of life of patients.
Evaluating the Association between Human Papillomavirus and Vulvar Cancer: A Comprehensive Analysis Using Bradford Hill Criteria
Authors: Yaz Hamid
Published: August 2024

Background: The role of human papillomavirus (HPV) in the development of vulvar cancer (VC) has been widely studied, but findings have been inconsistent. Despite numerous meta-analyses exploring the potential link between HPV and VC, the association remains controversial due to inherent limitations in meta-analytic methods. Objectives: To address this controversy, the study aims to investigate the potential link between HPV and VC using the Bradford Hill criteria, which offer a more comprehensive framework for establishing causation. Methodology: The study began by extracting all relevant studies on the association between HPV and VC from the PubMed database. The potential links were then assessed by examining the data using the major postulates of the Bradford Hill criteria. To ensure the reliability of the findings, the methodologies of the identified studies were critically evaluated to account for possible false-negative and false-positive results. Results: The assessment of previous studies against the Bradford Hill criteria revealed that the major postulates were not fulfilled. Conclusion: Based on the findings, it can concluded that there is no causal association between HPV and VC.
PTEN as a Novel Diagnostic and Prognostic Biomarker of Head and Neck Squamous Cell Carcinoma
Authors: Ali Zain , Ali Akbar
Published: August 2024

This review article explores phosphatase and tensin homolog (PTEN)’s role in head and neck squamous cell carcinoma (HNSCC) through comprehensive expression and methylation examinations, genetic mutation investigation, and prognostic evaluation. Using the UALCAN informational collection, PTEN expression examination uncovered a critical over-expression in HNSCC cells isolated from normal control samples, proposing its role in HNSCC multiplication. Further, analysis of PTEN expression across various clinical limits has shown critical up-regulation in different cancer development stages, racial groups, gender, and age classes within the context of HNSCC patients, suggesting its major role in cancer duplication. PTEN expression was validated by utilizing the GEPIA2.0 online tool, which showed PTEN expression was particularly significantly expressed in HNSCC cancer improvement when it appeared differently from normal control samples. Accordingly, examining PTEN validation across different phases of cancer advancement showed dysregulation in each of the four phases with the most raised expression in stage I and the least expression in stage IV. Thus, this study investigated the promoter methylation level of PTEN, figuring out a basic relationship between HNSCC samples and normal control samples. Analyzing promoter methylation across various clinical limits uncovered massive variations, with specific methylation patterns seen across malignant growth stages, race groups, gender, and age groups. Overall survival and disease-free survival (OS and DFS) utilizing the KM plotter tool showed a critical relationship between PTEN expression levels in HNSCC patients, showing high PTEN expression exhibited good overall survival when showed up distinctively comparable to low PTEN expression levels. In addition, in disease-free survival (DFS) evaluation HNSCC patients showing low PTEN expression experienced great DFS relative to HNSCC patients with high PTEN expression. Moreover, to validate PTEN expression against survival, the study examined the HNSCC patients into low and high-expression groups of PTEN. In HNSCC, low PTEN expression was connected with great overall survival (OS) when it appeared contrastingly relative to the high PTEN expression. In like manner, the study found that low PTEN expression level was connected with great DFS in HNSCC when it appeared contrastingly related to the high PTEN expression group. Genetic mutation analysis via cBioPortal identifies a minimal proportion of PTEN mutations in HNSCC, predominantly in-frame mutation, missense mutation, splice mutation, truncating mutation, and structural variant, indicating their basal significance in PTEN dysregulation within HNSCC. Further investigation of PTEN molecular components and their exchange inside the HNSCC microenvironment might disclose novel roads for designated treatment and accurate medication approaches in battling this harmful disease.
3D Collagen Gels: A Promising Platform for Dendritic Cell Culture in Biomaterials Research
Authors: Shanmugam Kirubanandan
Published: August 2024

The three-dimensional (3D) cell culture system has garnered significant attention in recent years as a means of studying cell behavior and tissue development, as opposed to traditional two-dimensional cultures. These systems can induce specific cell reactions, promote specific tissue functions, and serve as valuable tools for research in tissue engineering, regenerative medicine, and drug discovery. This paper discusses current developments in the field of three-dimensional cell culture and the potential applications of 3D type 1 collagen gels to enhance the growth and maturation of dendritic cells.
Clinical Efficacy of Laparoscopic Radical Colorectal Cancer Treatment for Colorectal Cancer and Its Effect on Immune Function
Authors: Liu Danguang
Published: August 2024

Objective: To explore the therapeutic effect of laparoscopic radical colorectal cancer treatment in colorectal cancer patients. Methods: A total of 50 colorectal cancer patients treated between August 2018 and August 2023 were randomly divided into two groups: Group A underwent laparoscopic radical colorectal cancer surgery, while Group B received open surgery. Clinical indicators, inflammatory factors, immune function indicators, and complications were compared between the two groups. Results: Group A showed significantly shorter operation times, faster recovery times, and reduced hospital stays compared to Group B. Additionally, Group A had less abdominal drainage and intraoperative bleeding (P < 0.05). Levels of interleukin (IL)-4, IL-6, ultrasensitive C-reactive protein (hs-CRP), and tumor necrosis factor-alpha (TNF-α) were lower in Group A compared to Group B (P < 0.05). Furthermore, immune function indicators, including CD3+, CD4+, CD8+, and CD4+/CD8+ ratios, were better in Group A (P < 0.05). The complication rate in Group A was also lower than in Group B (P < 0.05). Conclusion: Laparoscopic radical treatment for colorectal cancer is efficient and feasible, causing minimal immune function impairment and inflammatory response. It also shortens postoperative recovery time.