bluuebunny/crossref_metadata_2025 huggingface dataset:
Current Concepts of Tumour Metastasis
Authors: Barbour A , Gotley D C
Published: December 2023

Background: Tumour metastasis remains the principal cause of treatment failure and poor prognosis in patients with cancer. Recent advances in our understanding of the biology of metastasis are providing novel potential targets for anti-cancer therapies.

Aim: This paper reviews the current concepts in tumour metastasis.
Methods: A review of Medline publications relating to the molecular biology and therapy of human tumour metastasis was conducted.

Results and Discussion: Early metastasis models were based upon the premise of uninterrupted tumour growth, with the inevitable formation of distant metastases and eventual death of the patient. However, current research suggests that metastasis is an inefficient process governed by several rate-limiting steps, and that failure to negotiate these steps can lead to tumour dormancy. Successful metastatic tumour growth depends upon appropriate tumour-host microenvironment interactions and, ultimately, the development of vascularised metastases post-extravasation in the target organ. An understanding of the molecular mechanisms involved in this dynamic process will aid in the identification of therapeutic targets that may allow earlier diagnosis and more specific therapies for patients with metastasis.
Current Status in Imaging of Colorectal Liver Metastases
Authors: Tan A G S , Thng C H
Published: December 2023

Colorectal cancer is a common malignancy that often metastasizes to the liver. Evaluation of the liver for metastases is important for staging and prognosis. Resection of limited hepatic metastases can result in prolonged survival. Imaging is vital to select appropriate patients to avoid unnecessary surgery. A variety of modern imaging tools can be used to detect and characterise hepatic lesions. These include contrast enhanced helical computed tomography (CT), CT arterial portography, magnetic resonance imaging (MRI) and intraoperative ultrasound (IOUS). Each has their advantages as well as disadvantages. Besides accuracy, availability, cost and presence of expertise determine the optimal modality or combination of modalities to use. The appearance of metastases on imaging can be correlated with histopathological abnormalities. Though metastases can often be distinguished from benign lesions, their appearances are by no means pathognomonic. Follow-up imaging for interval change and for assessment of response is often required.
Neoadjuvant Chemotherapy in the Management of Colorectal Metastases: A Review of the Literature
Authors: Ong S Y K
Published: December 2023

Introduction: Five-year survival rates of between 20% and 45% are achievable in patients following hepatectomy for liver metastases from colorectal cancer. Sadly, a great majority of patients present with unresectable liver disease with virtually no long-term survival. This paper reviews the development and role of preoperative chemotherapy in trying to downstage unresectable liver disease.

Methods: The author retrieved most of the citations by performing a PubMed search for studies related to preoperative chemotherapy followed by surgical resection of liver metastases.

Results: Larger series have reported resectability rates ranging from 10% to 40% for unresectable colorectal liver metastases after treatment with preoperative chemotherapy. Chemotherapy generally consisted of oxaliplatin added to 5-fluorouracil/leucovorin administered in a chronomodulated fashion. A median of about 5 to 10 months of treatment was necessary for adequate tumour reduction. The 5-year survival rates, after surgery, in completely resected patients were between 30% and 60%. The majority of these patients will relapse, of which half of these will remain confined to the liver. Patients who are able to undergo a repeat hepatectomy may achieve long-term survival rates similar to the initial resection. Preliminary data from a recent study suggest that initial treatment with an oxaliplatin-containing regimen may lead to a higher resectability rate compared to an irinotecan-containing combination (18% versus 7%). Selective intra-arterial infusion has not demonstrated a clear advantage over systemic infusion and, if administered preoperatively, it may even compromise the safety of surgery.

Conclusions: Palliative chemotherapy remains the standard of care for unresectable colorectal liver metastases. However, in carefully selected patients, neoadjuvant chemotherapy may be able to downstage the disease adequately for curative resection.
The Molecular Biology of Peritoneal Carcinomatosis from Gastrointestinal Cancer
Authors: Jayne D G
Published: December 2023

Introduction: Peritoneal carcinomatosis is a frequent form of disease progression in gastrointestinal cancer, and all too often is a preterminal event with a median survival of only 6 months. Despite the introduction of aggressive surgical and chemotherapeutic approaches, any significant improvement in survival is unlikely until we better understand the molecular biology of peritoneal metastasis.

Methods: A Medline search and review of references was undertaken to identify all manuscripts in the English language concerned with peritoneal metastasis from gastrointestinal cancer.

Results: Peritoneal carcinomatosis involves a complex sequence of interdependent steps. The injured peritoneum is a rich source of cytokines and growth factors that facilitate tumour proliferation and invasion in the postoperative abdomen. Peritoneal tumour adhesion is dependent on adhesion molecules, such as CD44, and the ß-1 integrins. Invasion of the mesothelium involves, at least in part, a process of tumour-induced mesothelial apoptosis. Matrix metalloproteinases, such MMP-7, facilitate stromal invasion, but the role of other proteases ininvasion remains to be elucidated. To date, the significance of angiogenesis in the peritoneal metastatic cascade is unknown.

Conclusion: The molecular biology of peritoneal carcinomatosis is only just beginning to be understood. Further research into the mediators of the peritoneal metastatic cascade is needed if more effective therapeutic strategies are to be developed for this invariably fatal, yet unfortunately common, condition.
Navigating in the Sea of Science and Technology
Authors: Lim P
Published: December 2023

Let me begin by saying how deeply honoured I feel to be invited to deliver the 16th Gordon Arthur Ransome Oration. I thank the Master and the Council of the Academy of Medicine, Singapore, for bestowing on me this cherished honour.
NURSING STUDENTS’ ATTITUDES TOWARD INTIMATE PARTNER VIOLENCE AND THE INFLUENCING FACTORS
Authors: DAŞ GEÇİM Gözde Yıldız , ARDİC Aysun
Published: December 2023

Aim: The increasing incidence of violence is an important public health problem. Violence against women is increasing day by day. Most of this violence is intimate partner violence. In this context, nursing students' attitudes toward intimate partner violence and their experience with intimate partner violence are very important. The aim of this study was to determine the factors influencing the attitudes of nursing students toward intimate partner violence.

Method: The study was a descriptive-correlational design. The data were collected by using the Personal Information Form and Intimate Partner Violence Attitude Scale. In the analysis of the descriptive research statistics, the Pearson correlation, Kruskal-Wallis, Mann-Whitney-U and Binary logistic regression tests were used.

Results: It was found that 11.4% of the female students and 8.5% of the male students encountered intimate partner violence; of these students, 6.7% experienced physical, 5.2% experienced psychological, 4.4% experienced social, 2.1% experienced sexual and 1.5% experienced economic and digital intimate partner violence. It was found that nursing students whose mothers had attained a higher education level, who were exposed to domestic violence or who witnessed violence adopted a strong attitude against intimate partner violence.

Conclusion and Suggestions: This study emphasizes the necessity of increasing awareness of nursing students towards intimate partner violence and other types of violence, of adding violence as a compulsory course in the curriculum, and learning about legal responsibilities.
ASIYA BAĞLI HİPOKSİK BEYİN HASARI TANILI HASTANIN HEMŞİRELİK BAKIMI
Authors: TIRAŞ Olcay , KARACA SİVRİKAYA Sibel
Published: December 2023

Ası, dünyada en sık kullanılan intihar yöntemlerinden biri olarak bilinmektedir. Çoğunlukla ölümle sonuçlanan ciddi sorunlara yol açmaktadır fakat bireyin hayatta kalması sonrası tedavisi, yönetimi zor ve önem arz eden bir tablodur. Bu olguda incelemiş olduğumuz 44 yaşında kadın hasta kendini boynundan asması sonucu asıya bağlı hipoksik beyin hasarı tanısıyla acil servise alınmıştır. Hastanın ilk müdahaleleri yapıldıktan sonra izlem ve tedavisi için yoğun bakıma kabul edilmiştir. Olgunun rutin olarak yapılmış olan laboratuvar bulgularının ve izlemlerin değerlendirilmesi doğrultusunda elde edilen verilerle hemşirelik tanıları belirlenmiş ve bireyin hemşirelik bakımı gerçekleştirilmiştir. Hastanın yoğun bakım ünitesine kabulünden itibaren multidisipliner bir yaklaşımla hemşirelik bakımı verilerek bireyin izlemi gerçekleştirilmiştir. Bu olguda ası sonrası hipoksik beyin hasarı oluşan hastanın, yoğun bakım ünitesinde verilen hemşirelik bakımının sonuçlarının paylaşılması ve diğer meslektaşlarımıza rehberlik etmesi hedeflenmiştir. Bu konuda yapılan çalışmalar ve deneyimlerin paylaşılması, bu konudaki literatürün genişlemesine ve etkin hemşirelik girişimlerinin belirlenmesine katkı sağlayacaktır.
Pengaruh Perdagangan Karbon Terhadap Kondisi Ekologi di Indonesia
Authors: Samasta Nadia Azhar
Published: December 2023

Climate change and ecological degradation are two global phenomena that are of serious concern in Indonesia. To overcome these problems, carbon trading is one of the strategies used in an effort to reduce greenhouse gas emissions. The purpose of this study is to analyze the effect of carbon trading on ecological conditions in Indonesia. The research method used is a literature review model with descriptive qualitative data analysis techniques. The results showed that carbon trading has a positive influence in maintaining ecological sustainability in Indonesia through reducing greenhouse gas emissions and implementing sustainable practices. In conclusion, carbon trading plays an important role in influencing ecological conditions in Indonesia by making a significant contribution in reducing greenhouse gas emissions and improving sustainability practices.
Analisis Dampak Perilaku Sterilisasi Terhadap Kesehatan Kucing Betina dan Jantan
Authors: Azura Dedek , Nabila Mutiara , Damanik Alfina Sukma Hayati
Published: December 2023

Penelitian ini bertujuan untuk untuk mengetahui proses strerilisasi pada kucing betina dan jantan, dan untuk mengetahui manfaat yang didapatkan setelah kucing betina dan jantan disterilasikan. Penelitian ini dilakukan di Jalan Pinang Baris Desa Indrayaman Kecamatan Talawi Kabupaten Batu Bara. Penelitian ini dilaksanakan pada hari rentang waktu bulan Oktober 2023. Metode penelitian yang dilakukan adalah survey dan wawancara. Hasil dari penelitian ini diperoleh dari lima kucing yang dimana 3 ekor kucing betina yang diantaranya 1 persia dan 2 ekor jantan yang diantaranya 1 persia dan 1 lagi mixdom. Sterilisasi memberikan dampak positif dari steri yaitu kelima-lima kucing menjadi tidak stress, badan sehat, rambut lebat dan panjang, makan teratur, tidak berkeliaran, badan tidak luka-luka dikarenakan merebutkan betina, selalu bersih. Berdasarkan penelitian yang dilakukan dapat disimpulkan bahwa sterilisasi ini memberikan manfaat dan dampak positif pada sterilisasi pada kucing, terutama pada tingkat stress yang sangat mempengaruhi semua aspek pada kucing seperti Kesehatan, kebersihan, kebahagiaan.
Isolasi dan Identifikasi Mikroba Penyebab Kontaminasi dari Udara di Laboratorium Kultur Jaringan Tumbuhan UIN-SU Medan
Authors: Sucahyo Ahmad Imam , Manalu Kartika , Nasution Rizki Amelia
Published: December 2023

Plant tissue culture laboratory is a technique for growing cells, tissues or slices of plant organs which are often called explants in the laboratory in an artificial media containing aseptic (sterile) nutrients to become a whole plant. This research aims to know the isolation and identification of contaminating microbes in the plant tissue culture laboratory and to know the types of contaminating microbes in the plant tissue culture laboratory. This research was conducted from december 2022 to january 2023 at the Wahdatul Ulum plant tissue culture laboratory, uinsu medan with 5 main sampling points.the sampling point consists of an incubation room, planting room and practicum space which is divided into 3 collection points. Staining tests and biochemical tests are conducted at the USU faculty of mathematics and natural sciences microbiology laboratory. The results of the study found 23 bacterial isolates that contamined the wahdatul ulum plant tissue culture laboratory at UINSU Medan consisting of the genera bacillus, lactobacillus, streptobasil, aeromonas, pseudomonas, serratia, bacteroides and acinetobacter while the contaminating fungi were Mucor sp. Contamination occurs due to mobility and activity in the laboratory room.
Penerapan Model PBL Berbantuan Media Interaktif Powerpoint Untuk Meningkatkan Hasil Belajar Pada Materi Ekosistem di Kelas X
Authors: Atikah Isma , Usman Ali , Ernayanti Retno
Published: December 2023

Pendidikan merupakan pembelajaran yang berlangsung secara berkelompok untuk diwariskan kepada generasi berikutnya dalam bentuk pengetahuan dan keterampilan. Seorang pendidik harus mampu menciptakan ide-ide baru dalam mengajar untuk seperti menggunakan berbagai macam kombinasi teknik taktik, strategi, ataupun metode- metode pembelajaran masa kini yang lebih relevan dengan perkembangan sains dan teknologi masa kini (era digital) adalah Problem Based Learning (PBL). Penggunaan teknologi dalam pembelajaran merupakan tuntutan yang relevan dengan perkembangan dunia pendidikan saat ini. Selain itu, penggunaan teknologi dalam proses pembelajaran memiliki daya tarik sendiri bagi siswa karena lebih mudah dipahami dan dapat meningkatkan rasa antusias mereka terhadap pembelajaran. Dengan demikian media pembelajaran menjadi salah satu penunjang yang efektif dalam membantu terjadinya proses pembelajaran. Tujuan penelitian ini untuk mendeskripsikan Penerapan Model PBL Berbantuan Media Interaktif Powerpoint Untuk Meningkatkan Hasil Belajar Pada Materi Ekosistem di Kelas X. Jenis penelitian ini merupakan Penelitian Tindakan Kelas (PTK) dengan menggunakan pendekatan kualitatif dan analisis deskriptif kualitatif. Dengan pengelolaan data menggunakan microsoft excell. Penelitian dilakukan di SMA Grujugan dengan subjek penelitian adalah seluruh siswa kelas X.1 berjumlah 29orang. Hasil penelitian ini menunjukkan bahwa pada siklus I terdapat peningkatan hasil belajar biologi siswa di kelas X.1 yang dibuktikan dengan nilai rata-rata post test sebesar 80,51 dengan persentase ketuntasan 62,06% dan jumlah siswa yang mencapai nilai KKM sebanyak 18 siswa. Pada siklus II hasil belajar mengalami peningkatan menjadi 88,79 dengan persentase ketuntasan 93,10% dan jumlah siswa yang mencapai nilai KKM sebanyak 27 siswa.
Strategi Pembelajaran Berdiferensiasi Berdasarkan Profil Belajar Peserta Didik pada Materi Sistem Imun Biologi SMA
Authors: Maulidia Feny Rahma , Prafitasari Aulya Nanda , Wulandari Fifit
Published: December 2023

Berdasarkan hasil observasi di SMAM 2 Wuluhan, bahwa dalam pembelajaran biologi guru masih mengandalkan teknik ceramah yang dapat membuat sebagian siswa bosan, di lain waktu guru juga menjelaskan materi dengan gambar atau video, namun beberapa siswa lebih menyukai kegiatan belajar yang melibatkan gerakan, seperti observasi atau pembelajaran yang diselingi dengan sebuah permainan seru. Tujuan penelitian ini adalah meningkatkan hasil belajar biologi dengan menggunakan model Problembased learning (PBL) dengan media puzzle gambar. Jenis penelitian ini adalah penelitian tindakan kelas. Penelitian ini dilaksanakan selama dua siklus. Tehnik pengumpulan data yang dilakukan adalah wawancara, observasi, angket siswa dan hasil evaluasi siswa. Wawancara dilakukan kepada guru biologi dan siswa kelas XB, observasi dilakukan ketika pra siklus pembelajaran, angket siswa dilakukan untuk mengetahui gaya belajar siswa dan hasil evaluasi siswa dilakukan berdasarkan nilai posttest siswa setelah akhir pembelajaran dalam siklusnya. Data yang yang diperoleh kemudian dianalisis menggunakan Teknik analisis deskriptif kuantittatif. Berdasarkan hasil penelitian bahwasannya hasil belajar siswa dari prasiklus 4,8% mengalami tingkat keberhasilan dari siklus I 71,43% menjadi 84,28% di siklus II. Dengan demikian penerapan model pembelajaran model problembased learning dengan picture puzzle pada biologi dapat meningkatkan hasil belajar pada materi perubahan lingkungan.
Analisis Permasalahan dalam Penerapan Media Pembelajaran Inovatif Mata Pelajaran IPA di SD pada Kurikulum 2013 dan Kurikulum Merdeka
Authors: Aulia Annisa , Rahmadita Annisa Aulia , Putri Azlia Anugerah
Published: December 2023

The purpose of this research is to analyze issues in the implementation of innovative learning media in science education at elementary schools through the 2013 Curriculum and the Merdeka Curriculum. The subjects of this study are fifth-grade teachers in public elementary schools located in Jakarta. The research employs a qualitative descriptive method, using techniques such as interviews and observations. The results of the study show that the learning media plays a crucial role in the implementation of learning activities in the classroom, as well as in enhancing students' motivation to learn and their interest in the subject.
Improving Indonesian Language Learning Outcomes Through Quizizz Learning Media In Elementary Schools
Authors: Wahdian Agus , Kusyairi Kusyairi , M. Khoiri M. Khoiri
Published: December 2023

The COVID-19 epidemic has significantly affected the education sector, resulting in a shift from traditional offline learning to online platforms.   Quizizz is a media tool that teachers can utilize during online learning.   The objective of this study is to ascertain whether the utilization of Quizizz as a learning medium has an impact on students' academic achievements.   The research methodology employed is quantitative, utilizing a pre-experimental research design.   The participants consisted of 26 fourth-grade kids.   The data collection methods employed included the utilization of tests and questionnaires.   The pre-test score yielded a mean result of 65.19, whereas the post-test score yielded a mean result of 88.08.   Based on the research data analysis conducted using SPSS version 25, the results of the paired sample t-test indicate that the two-tailed significance value (sig) is 0.000, which is less than the significance level of 0.05. Therefore, we may conclude that the null hypothesis (H0) is rejected and the alternative hypothesis (H1) is accepted.   The study findings suggest that the utilization of Quizizz as a learning tool has a significant impact on students' academic performance in mathematics when accessed online at SDN Gunggung Sumenep.
Transformasi Pendidikan Guru SD: Analisis Program TEMA PGSD dalam Meningkatkan Kualitas Pengajaran dan Prestasi Siswa
Authors: Yazid M. Hikmal
Published: December 2023

In response to the imperative need for enhancing primary school education, this study delves into the transformative impact of the TEMA PGSD program on the professional development of elementary school teachers. The article's objective is to analyze how the program contributes to elevating teaching quality and student achievement. Through a mixed-methods approach, combining participant surveys and in-depth classroom observations, this research investigates the practical implications of TEMA PGSD. The findings underscore a notable positive shift in pedagogical practices among participating teachers, leading to observable improvements in student performance across various subjects. With a concise yet comprehensive overview of the program's methodology, which prioritizes interactive learning and practical application, this study provides valuable insights for educators, policymakers, and researchers. The background highlights the pressing need for effective teacher training, setting the stage for the relevance of the TEMA PGSD initiative. The article concludes by emphasizing the program's potential as a transformative model for primary school teacher education. This research not only addresses a critical gap in current educational strategies but also offers practical solutions to enhance the overall quality of primary education, laying the groundwork for future advancements in teacher professional development.
Meningkatkan Kemampuan Berpikir Kritis Matematika Peserta Didik di Sekolah Dasar pada Era Digital
Authors: Tinambunan Rani Rosaria , Pratiwi Sarah , Ulandari Neni , Ni’mah Nadhira Tita An
Published: December 2023

This research aims to assess strategies for improving elementary school students' critical thinking skills using a literature review approach. Analysis of previous research related to critical thinking skills was carried out to identify more effective and efficient efforts. The hope is that the results of the literature review can provide valuable insight for educators in improving elementary school students' critical thinking skills. The research findings involved a review of 15 journals, with emphasis on reference sources, sample types, research methods, interventions, and journal review results. In conclusion, increasing students' critical thinking skills can be achieved through various learning models, such as Problem Based Learning, Discovery Learning, Problem Solving, Inquiry, and Cooperative, especially in the context of mathematics learning.
Analysis of Qaul Qadim Imam Syafi'i in the Social History of Islamic Law
Authors: Fawwaz Aulia Fadhilah
Published: December 2023

This research analyzes how qaul qadim and how ijtihad are viewed by Imam Syafi'i which is studied from several aspects, namely from historical, social and Islamic legal aspects. This research has the main aim of examining how qaul qadim is from a historical perspective, namely how history was formed and the birth of qaul qadim and then how social changes and Islamic law have affected qaul qadim which was mandated by one of the fiqh scholars, namely Imam Syafi'i, in establishing Islamic law. This research is research with a normative theological approach, namely a theological-normative approach, namely by looking at the texts of the Koran and al-Hadith which are the main sources in determining Islamic law and this type of research. The sociological approach is research whose object of study is seen in terms of different fatwa factors. different to accommodate legal problems that arise at this time and require ijtihad, then Islamic law will do it. This research shows that qaul qadim and ijtihad carried out by Imam Syafi'i are influenced by various factors in their determination, including social, political, cultural, geographical and scientific factors which influence the dynamics of legal determinations carried out by mujtahids like Imam Syafi'i.
Effect of cystamine on gastric propulsive function and gas exchange in the rat model of radiation-induced myeloablation
Authors: Vakunenkova OA , Ivnitsky JuYu , Danilova OA , Schäfer TV , Rejniuk VL
Published: December 2023

Radiation exposure of recipients before hematopoietic stem cell transplantation can cause gastrointestinal (GI) stasis. It is associated with complications of myeloablative radiation therapy: delayed vomiting, excess bacterial growth, endotoxicosis, systemic inflammation, and sepsis. The study was aimed to assess the possibility of GI stasis prevention by intragastric administration of cystamine dihydrochloride when using radiation-induced myeloablation. The severity of GI stasis, levels of enterocyte markers in the small intestinal tissues and the indicator of intestinal endotoxicosis, urinary indican excretion, were assessed in rats 72 h after the single total-body X-ray exposure to the dose of 9.64 Gy (1.1 LD99/30); the animals’ whole body oxygen consumption was recorded daily. Irradiation caused GI stasis with predominant gastric stasis, the 1.5–4.8-fold decrease in the cholinesterase and alkaline phosphatase activity in the small intestinal tissues, doubled the urinary indican excretion, the whole body oxygen consumption reduction by 17–32%. Cystamine administration generally prevented gastric stasis, but had no significant effect on the characteristics of radiation-induced enterocytopenia and did not prevent accumulation of chyme in the caecum, hyperindicanuria, radiation-induced spleen hypotrophy, and decrease in gas exchange rate. Cystamine is promising for testing in large animals as a selective agent for emergency prevention of gastric stasis during myeloablative radiation therapy.
Estudiantes de la UTN fueron seleccionados para realizar pasantía en la Universidad de Osnabrück, Alemania
Authors: Gutiérrez Rosales Stephanie
Published: December 2023

Como parte del convenio entre la Universidad Técnica Nacional (UTN) y la Universidad de Osnabrück (UOS) Alemania, para desarrollar un proyecto de cooperación bilateral, que permita fortalecer el sistema de la educación técnica, dos estudiantes de la carrera de Ingeniería en Ciencias Forestales y Vida Silvestre de la Sede de Atenas fueron elegidas para realizar una pasantía académica. Wendy Tatiana Alfaro Méndez fue considerada por la prestigiosa universidad alemana, debido al proyecto de investigación que realizó sobre los acueductos comunales de la región en la que vive, específicamente, con la Asociación Liga de Comunidades Unidas en Conservación del Agua cuyo tema fue "Proteger y conservar el recurso hídrico para las generaciones presentes y futuras a través de la educación, y el fortalecimiento de los acueductos de la cuenca del río Balsa", conformada por ocho comunidades de la región que se abastecen de este recurso.  Una de las labores del estudio, estuvo orientada en trazar senderos analizar los tipos de suelo, las pendientes y la vegetación. En el futuro se espera caracterizar el ecosistema identificando la flora y fauna, para que a lo largo del recorrido los visitantes del sendero puedan conocer más sobre el lugar. Por su parte la estudiante, Mónica González Angulo, propuso un programa para aplicar sus conocimientos y generar un impacto tangible en la comunidad de Puerto Níspero, en el Golfo de Nicoya, a través de la evaluación de manglares que se encuentran en proceso de restauración.
Thriving at the University Level: Student Maintains Her Sanity in a World of Chaos
Authors: Mayweathers Dr. Denise Gates
Published: December 2023

The purpose of this paper was to explore the lived experiences of a woman from a non-dominant racial group in academia. It examined some of the obstacles to effective organizational socialization she encountered, which manifested as micro-aggressive behavior and other marginalizing activities. When the light at the end of the tunnel began to flicker, she found innovative strategies to attain her goals. This paper emphasized the tactics utilized by a woman to maintain her sanity in a world of chaos. It detailed some of her barriers to success from the perspective of organizational socialization, and it identified strategies that enabled her to thrive.
Semblanza del Dr. Ricardo Plancarte Sánchez; De Michoacán para el Mundo.
Authors: Reyes Torres Ignacio , Hernández Porras Carolina
Published: December 2023

Semblanza del Dr. Ricardo Plancarte Sánchez; De Michoacán para el Mundo.
E-Authentication System using QR Code and OTP
Authors: Miss. Shweta Kamble  , Miss. Pooja Kendre  , Miss. Ayesha Siddiqua  , Mr. Deshpande G. R
Published: December 2023

This paper proposes an authentication system that combines One-Time Password (OTP) and Quick Response (QR) code technologies to enhance security and user experience. The system generates an OTP and a unique QR code for each authentication attempt, which can be scanned using a mobile device to complete the authentication process. The QR code contains encrypted information about the user's identity and the OTP, which is verified by the server. The proposed system provides a secure, convenient, and efficient method for user authentication, which is crucial in today's digital world. An e-authentication system that uses OTP and QR code technology is a secure and efficient method for authenticating users in online transactions. This system combines the benefits of OTP and QR code technology to provide a two-factor authentication mechanism that is convenient for users and effective in preventing unauthorized access. This system aims to address the vulnerabilities of traditional username and password authentication by providing an additional layer of security through two-factor authentication. the system aims to prevent unauthorized access to online services and transactions. The system aims to provide a userfriendly and convenient authentication method that can be easily integrated into existing online platforms. It protect sensitive information and ensure that only authorized users can access online services and transactions
The Publishing Business
Authors: Smith Kelvin , Ramdarshan Bold Melanie
Published: December 2023

Are you considering a career in the world of publishing, or simply want to understand more about the industry? If so, The Publishing Business will take you through the essential publishing activities performed in editorial, rights, design, production, sales and marketing departments.

International examples from across the industry, from children's books to academic monographs, demonstrate key responsibilities at each stage of the publishing process and how the industry is adapting to digital culture. This 3rd edition has been updated with more on the role of self-publishing, independent publishers, audio books, the rise of poetry and non-fiction and how the industry is facing up to challenges of sustainability, inclusivity and diversity.

Beautifully designed and full of insight and advice from practitioner interviews, this is an essential introduction to a dynamic industry.

Interviewees include:

Anne Meadows, Commissioning Editor at Granta and Portobello Books

Zaahida Nabagereka, Head of Social Impact at Penguin Books UK

Ashleigh Gardner, Senior Vice President, Managing Director Global Publishing, Wattpad

Caroline Walsh, Literary Agent, David Higham Associates

Peter Blackstock, VP, Deputy Publisher, Grove Atlantic/Publisher, Grove Press UK

Amy Ellis, Head of Rights and Permissions, Publishers' Licensing Services

Victoria Lawrance, Rights Manager, Bloomsbury Publishing Plc

Shaun Hodgkinson, COO, Dorling Kindersley

Thomas Truong, Publishing Director, Little Tiger Group

Jenny Blenk, Associate Editor, Dark Horse Comics

Jeanette Morton, Digital Publisher, Oxford University Press

Maria Vassilopoulos, Publishing Sales, Uni of Wales Press and Calon Books

Ian Lamb, Head Of Children's Marketing and Publicity, Simon and Schustere
Alice Munro’s Late Style
Authors: Thacker Robert
Published: December 2023

Focusing on Alice Munro’s last three books, this book examines the differences between these volumes and the rest of her work to analyse the emergence and the difference of her 'late style'.

Alice Munro has effectively reshaped the short story as a form. This book focuses on Munro’s art of recursion - an approach that has been evident throughout her career but came to the fore in her last three books, The View from Castle Rock (2006), Too Much Happiness (2009) and, especially, Dear Life (2012). This recursion and return manifest themselves not only in Munro's return to previously published pieces, but also to her Scottish heritage, which can be read as entrance to her own understanding of herself and her life. Its provenance, displayed through archival evidence, is complex yet reveals a writer intent on a precise late style.

Munro's final works serve as a coda to both her late style and to her entire career as arguably one of the finest short story writers ever to put pen to paper.
21st-Century British Gothic
Authors: Horton Emily
Published: December 2023

In this innovative re-casting of the genre and its received canon, Emily Horton explores fictional investments in the Gothic within contemporary British literature, revealing how such concepts as the monstrous, spectral and uncanny work to illuminate the insecure, uneven and precarious experience of 21st century life. Reading contemporary works of Gothic fiction by Helen Oyeyemi, Kazuo Ishiguro, Sarah Moss, Patrick McGrath and M.R. Carey alongside writers not previously grouped under this umbrella, such as Brian Chikwava, Chloe Aridjis and Mohsin Hamid, Horton illuminates the way the Gothic has been engaged and reread by these contemporary writers to address the many cultural anxieties invoked living under neocolonial and neoliberal governance, including terrorism, migration, homelessness, racism, and climate change.

Marshalling new modes of diasporic and cross-disciplinary critical theory concerned with the violent dimensions of contemporary life, this book sets the Gothic aesthetics in such works as White is for Witching, Double Vision, Never Let Me Go, The Wasted Vigil and Ghost Wall against a backdrop of key events in the 21st century. Drawing connections between moments of anxiety, such as 9/11, the wars in Afghanistan and Iraq, ecological disaster, the refugee crisis, Brexit, the pandemic, and the Gothic, Horton demonstrates how British literature mediates transnational experiences of trauma and horror, while also addressing local and national insecurities and preoccupations. As a result, 21st century British Gothic can be seen to test geographical, psychological, cultural, and aesthetic borders, as it seeks to expose an often spectralised experience of human and planetary vulnerability, and as it speaks back against the brutality of global capitalism.
Theatre and the Threshold of Death
Authors: Gough Kathleen M.
Published: December 2023

On the eve of a global pandemic, Kathleen Gough, a theatre professor, becomes immersed in the lives of five artist-mystics, each of whom is a pioneer in her field: Hildegard of Bingen (1098-1179), the first known musical composer; Eleanora Duse (1858-1924), the first modern actor in the Western world; Simone Weil (1909-1943), philosopher, activist, and mystic, whom Albert Camus called “the only great spirit of our time”; Marina Abramovic (b. 1946), “the grandmother of performance art”; and Hilma af Klint (1862-1944), the first known (and belatedly acknowledged) abstract painter. Each time Gough crosses a threshold into their world, she is compelled to attend courses, seminars and workshops that are simultaneously about dying and healing.

Curious to learn more about the relationships between art practice, dying, and healing, Gough imagines the five artists as wisdom teachers in a mystery school. In a series of eight lectures, she turns to performance theory to provide a framework for engaging with the unknown world. In Theatre and the Threshold of Death, Gough makes a persuasive argument for the world-making power of relational thinking in our increasingly polarized age.
Talking Conflict
Authors: Wittmann Anna M.
Published: December 2023

In today's information era, the use of specific words and language can serve as powerful tools that incite violence—or sanitize and conceal the ugliness of war. This book examines the complex, "twisted" language of conflict.

Why is the term "collateral damage" used when military strikes kill civilians? What is a "catastrophic success"? What is the difference between a privileged and unprivileged enemy belligerent? How does deterrence differ from detente? What does "hybrid warfare" mean, and how is it different from "asymmetric warfare"? How is shell shock different from battle fatigue and PTSD? These are only a few of the questions that Talking Conflict: The Loaded Language of Genocide, Political Violence, Terrorism, and Warfare answers in its exploration of euphemisms, "warspeak," "doublespeak," and propagandistic terms.

This handbook of alphabetically listed entries is prefaced by an introductory overview that provides background information about how language is used to obfuscate or minimize descriptions of armed conflict or genocide and presents examples of the major rhetorical devices used in this subject matter. The book focuses on the "loaded" language of conflict, with many of the entries demonstrating the function of given terms as euphemisms, propaganda, or circumlocutions. Each entry is accompanied by a list of cross references and "Further Reading" suggestions that point readers to pertinent sources for further research. This book is ideal for students—especially those studying political science, international relations, and genocide—as well as general readers.
The Triumph of Reality TV
Authors: Edwards Leigh H.
Published: December 2023

This book provides an up-to-date account of how reality TV has developed, why it has become the most popular genre on television today, and how the explosion in reality TV signals new developments in American media culture.

The reasons behind reality TV's continued popularity go beyond the sensationalism and low production cost of these programs: there is much more to the genre's continued success than just escapism or “guilty pleasure” TV. The Triumph of Reality TV: The Revolution in American Television identifies and explores five key media trends reality TV has used to continually draw in viewers and ensure success. These media trends include innovations in storytelling, making emotional appeals to viewers, and applying content from television to other media such as films, music albums, webisodes, online games, and smart phone apps.

Author Leigh H. Edwards also analyzes how reality TV shows target themes of social conflict, such as changing ideas of the American family, and address common anxieties and tensions in American society such as gender, race, class, and economic struggle. A wide variety of reality shows—including American Idol, Celebrity Rehab, Jackass, Run's House, Survivor, and The Hills—are profiled. An appealing read for students, scholars, and general readers alike, this book provides fascinating insights into the complexities of a seemingly simplistic form of mass entertainment.
The 100 Most Significant Events in American Business
Authors: Skrabec   Jr. Quentin R.
Published: December 2023

This reference book details the top 100 groundbreaking events in the history of American business, featuring case studies of successful companies who challenged traditional operating paradigms, historical perspectives on labor laws, management practices, and economic climates, and an examination of the impact of these influences on today's business practices.

Throughout history, important commercial developments in the United States have made it possible for American companies to leverage tough economic conditions to survive—even thrive in a volatile marketplace. This reference book examines the top 100 groundbreaking events in the history of American business and illustrates their influence on the labor laws, business practices, and management methodologies of corporate America today.

The 100 Most Significant Events in American Business: An Encyclopedia depicts the chronological order of events contributing to the evolution of American business, with an emphasis on the commercial innovations of each period. The book explores the origins of successful brands, including Apple, Wal-Mart, and Heinz; demonstrates the successful collaboration between public and private sectors illustrated by the Erie Canal, Hoover Dam, and the interstate highway system; and depicts the commercial impact of major economic events from the Panic of 1857 to the Great Recession of 2010.
American Gangsters, Then and Now
Authors: Hendley Nate
Published: December 2023

A detailed compendium of American gangsters and gangs from the end of the Civil War to the present day.

American Gangsters, Then and Now: An Encyclopedia ranges from Western outlaws revered as Robin Hoods to the Depression's flamboyant bootleggers and bank robbers to the late 20th century's drug kingpins and "Dapper Dons." It is the first comprehensive resource on the gangster's historical evolution and unshakable grip on the American imagination.

American Gangsters, Then and Now tells the stories of a number of famous gangsters and gangs—Jesse James and Billy the Kid, the Black Hand, Al Capone, Sonny Barger and the Hell's Angels, the Mafia, Crips and Bloods, and more. Avoiding sensationalism, the straightforward entries include biographical portraits and historical background for each subject, as well as accounts of infamous robberies, killings, and other events, all well documented with both archival newspapers and extensive research into the files of the FBI. Readers will understand the families, the places, and the times that produced these monumental criminals, as well as the public mindset that often found them sympathetic and heroic.
A Battlefield of Values
Authors: Burgard Stephen D. , Hubbard Benjamin J.
Published: December 2023

Differing moral views are dividing the country and polarizing the left and the right more than ever before. This book offers unique solutions to improve communication and understanding between the two factions to fix our fractured political system.

Morality is at the heart of political contention in American society. Unfortunately, our polarized belief systems severely inhibit the achievement of bipartisan compromises. A Battlefield of Values: America’s Left, Right, and Endangered Center provides a candid but nonjudgmental examination of what people think and believe—and how this informs our divisions over core values. By addressing how individuals believe rather than how they vote, the book illuminates why 21st-century America is so conflicted politically and religiously; exposes what matters most to those on the right and left of the political, religious, and cultural spectrum; explains why the members of the endangered center in American life—the moderates—are struggling to make sense of the great divide between conflicting ideologies; and predicts how a degree of reconciliation and detente might be possible in the future.

Authors Stephen Burgard and Benjamin J. Hubbard build a powerful case for how authentic communication between political factions is integral to bettering our society as a whole. Along the way, they illustrate the impact of religion and media on American belief systems and also explore the inability of news media to serve as mediators of this dilemma. This work will fascinate lay readers seeking perspective on our current political stalemate as well as serve college students taking courses in political science, communications, journalism, anthropology, or religious studies.
Beyond Sand and Oil
Authors: Caravelli Jack
Published: December 2023

This text provides an up-to-date overview of nuclear weapons in the politically fragile Middle East, discussing the evolution and future of national programs, as well as the current challenge posed by Iran.

Shortly after World War II, the Middle East became a locus for nations seeking to acquire nuclear missiles and the means to deliver them to their enemies. Israel was the first; Libya and Iraq followed suit. Pakistan now possesses a substantial number of nuclear weapons, to which longtime rival India will no doubt respond. The implications of the political and security dynamics of the Middle East for the United States and other nations are truly profound and sobering.

Beyond Sand and Oil provides a nation-by-nation overview of the evolution of nuclear weapons programs in what is likely the world's most politically unstable region. A detailed assessment of Iran's prospects for becoming a nuclear weapons state—and how Israel, the Arab world, and the international community will respond to that outcome—is also included.
Beyond Stereotypes in Black and White
Authors: Treadwell Henrie M.
Published: December 2023

This book spotlights the plight of African American boys and men, examining multiple systems beyond education, incarceration, and employment to assess their impact on the mental and physical health of African American boys and men—and challenges everyday citizens to help start a social transformation.

Beyond Stereotypes in Black and White: How Everyday Leaders Can Build Healthier Opportunities for African American Boys and Men exposes the daily plight of African American boys and men, identifying the social and policy infrastructure that ensnares them in a downward spiral that worsens with each exposure to our system that offers unemployment, low-wage work, marginalization, and incarceration.

The book examines why African American boys and men are more sickly and die younger than any other racial group in the United States, have very few health coverage options, and are consistently incarcerated at rates that are wildly disproportionate to their representation of the U.S. population; and it documents how this tremendous injustice comes with a cost that burdens all groups in American society, not just African Americans. Additionally, the author challenges readers to see that all of us must act individually and collectively to right this social wrong.
Books on Early American History and Culture, 2001–2005
Authors: Irwin Raymond D.
Published: December 2023

This volume offers a complete listing and description of books published on early America between 2001 and 2005.

An extraordinary research tool, Books on Early American History and Culture, 2001-2005: An Annotated Bibliography is part of a series listing materials on the history of North America and the Caribbean from 1492 to 1815. This volume includes monographs, reference works, exhibition catalogs, and essay collections published between 2001 and 2005.

Each entry provides the name of the work, its author(s) or editor(s), publisher, date of publication, ISBN and/or OCLC number(s), and the Library of Congress call number. Following each detailed citation, there is a brief summary of the work and a list of journals in which it has been reviewed. Organized thematically, the book covers, among many other topics, exploration and colonization; maritime history; environment; Native Americans; race, gender, and ethnicity; migration; labor and class; business; families; religion; material culture; science; education; politics; and military affairs.
A Concise History of Economists' Assumptions about Markets
Authors: Mitchell Robert Edward
Published: December 2023

This open-minded, multidisciplinary approach challenges existing world views on the endogenous and exogenous forces that drive markets and economies.

Nine narrative chapters and a conclusion provide an accessible history of key premises and assumptions in the mental models proposed by several major economists since the 1776 publication of Adam Smith's The Wealth of Nations and show how—and why—those models and their underlying assumptions have changed over time. The book addresses the legacies of major economists, describes their historical and analytical influence, documents the interaction among various schools of thought as well as how they differ, and the implications that this history has for economics and the policy sciences in the decades ahead.

The author focuses on the mental maps economists have created in an attempt to understand the forces that destroyed "order," explaining how these maps incorporate a non-mathematical presentation of evolving dictionaries, novel analytical perspectives, new evidence, and a reliance on value assumptions. He traces the underlying assumptions, continuities, and differences among major economists including Adam Smith, Thomas Malthus, David Ricardo, Alfred Marshall, John Maynard Keynes, Karl Marx, Thorstein Veblen, and Joseph Schumpeter. Readers will grasp how the classic theories still influence economists' mental models today and come away with a basic economic literacy that puts this important social science in historical context. This is essential reading for all the social and policy sciences.