bluuebunny/crossref_metadata_2025 huggingface dataset:
Two years post-COVID-19: evaluating the impact on Brazil’s breast cancer early detection program
Authors: Antonini Marcelo , Mattar Andre , Pinheiro Denise Joffily Pereira da Costa , Teixeira Marina Diogenes , Amorim Andressa Gonçalves , Ramos Marcellus do Nascimento Moreira , Ferraro Odair , Lopes Reginaldo Guedes Coelho
Published: November 2024

Objective: This study aimed to evaluate the impact of the COVID-19 pandemic on mammographic screening in Brazil over a 9-year span (2015–2023), focusing on BI-RADS® results, breast cancer diagnosis rates, and staging. Methodology: This ecological observational study used retrospective data from Brazil’s mammographic screening database, DATASUS – SISCAN, covering females aged 50–69 years. We analyzed the number of mammograms, BI-RADS® results, and cancer staging, using a chi-square test to assess the variation from expected frequencies, with an alpha level of 0.05 for statistical significance. Results: From 2015 to 2023, 23,851,371 mammograms were performed, with 542,889 (2.3%) diagnostic and 23,308,482 (97.7%) screening. Of these, 15,000,628 met the inclusion criteria. In 2020, mammograms decreased by 39.6%, followed by a 12.6% drop in 2021. There was a slight increase in 2022 and a significant rise of 17.9% in 2023, though not reaching the anticipated 2,750,000 annual screenings. There was a notable increase in BI-RADS® 4 and 5 post-pandemic, suggesting a shift in staging patterns. Early-stage diagnoses were higher than expected pre-pandemic, while later-stage diagnoses (III and IV) increased post-pandemic, indicating potential delays in detection. Conclusion: The study revealed significant shifts in mammographic screening and breast cancer diagnosis over 9 years. There was a marked decrease during the pandemic with a subsequent rebound. The increase in BI-RADS® categories 4 and 5 and the shift to later-stage diagnoses post-pandemic underscore the pandemic’s impact on the timeliness and stage of breast cancer detection in Brazil.
Prediction of pathologic complete response to chemoimmunotherapy in triple-negative breast cancer using tumor-infiltrating lymphocytes: exploiting cutoff values
Authors: Bonadio Renata Rodrigues da Cunha Colombo , Tavares Monique , Bines Jose , Anjos Carlos Henrique dos , Zucchetti Bruna Migliavacca , Ferrari Anezka , Testa Laura , Barroso-Sousa Romualdo
Published: November 2024

Objective: Triple-negative breast cancer (TNBC) prognosis is significantly influenced by tumor-infiltrating lymphocytes (TILs), but the lack of validated cutoff values limits their clinical applicability. This study aimed to assess TILs as predictors of pathologic complete response (pCR) within the Neo-Real study, a multicenter, real-world data investigation on neoadjuvant pembrolizumab plus chemotherapy (P+CT) for TNBC. Methodology: TILs were evaluated using the standardized methodology of the International TILs Working Group. Logistic regression and receiver operating characteristic (ROC) curve analysis were performed to evaluate the predictive ability of TILs and multivariable models for pCR. Results: The analysis included 128 patients. The pCR and results of ROC curve analysis for each TIL’s cutoff were as follows: 10%: pCR of 39% for TILs <10% vs. 69% for TILs ≥10% (AUC 0.635, accuracy 66.7%, sensitivity 78%, specificity 50%); 30%: pCR of 52.2% for TILs <30% vs. 78.8% for TILs ≥30% (AUC 0.608, accuracy 56.2%, sensitivity 35.6%, specificity 86%); 50%: pCR of 55.4% for TILs <50% vs 87.5% for TILs ≥50% (AUC 0.575, accuracy 50.4%, sensitivity 19.1%, specificity 96%). A cutoff of 10% demonstrated the highest accuracy for pCR, while high specificity was observed at a cutoff of 50%. The probability of residual disease if TILs ≥50% is considerably low. A multivariable logistic regression model, using TILs (≥10% vs. <10%), Ki67 (≥50% vs. < 50%), and tumor stage (III vs. II), exhibited the highest AUC (0.688) for predicting pCR. Conclusion: Our study underscores the predictive value of TILs for pCR following neoadjuvant P+CT for TNBC. Further enhancement of TILs’ predictive potential may be achieved through multivariable models. The cutoff value of ≥50% identified patients with a very high probability of pCR. The results reinforce TILs’ use as a biomarker for treatment de-escalation, especially for TILs ≥50%.
Management disparity in elderly female with breast cancer following mastectomy: a cross-sectional study
Authors: Ramos Lilian de Sá Paz , Moura Larissa Matos Almeida , Biazús Jorge Villanova
Published: November 2024

Objective: This study aimed to evaluate the oncologic approach of elderly women (≥70 years old) diagnosed with stage I–III breast cancer who undergoing mastectomy and compare with younger patients. Methodology: In this single-center study, we included a total of 930 female patients with early breast cancer who were undergoing mastectomy from January 2018 to December 2022 at Aristides Maltez Hospital. For this analysis, patients were divided in two groups (group 1: ≥70 years and group 2: <70 years). We performed review of medical records and collected clinical and sociodemographic characteristics, in addition to data of surgery, systemic treatments and pathological reports. This study was approved by the Research Ethics Committee of Institute of Health Sciences at the Federal University of Bahia, with CAAE number 57203622.0.0000.5662. Results: Notably, 96 patients (10.3%) were 70 years old or older. Between the two groups, there was no statistically significant difference in demographics features or clinical stage, but group 1 had slightly more clinically node-positive (56.7% vs. 41.4%; p=0.038). Group 1 was submitted to more up-front surgery, even in more advanced stages, more axillary dissection (86.5% vs. 73%; p=0.006), but, in contrast, received less neoadjuvant chemotherapy (33.3% vs. 50.4%; p <0.01). Immediate breast reconstruction was performed less frequently in elderly patients (1% vs. 23.9%; p <0.01). Furthermore, elderly women received less adjuvant anthracyclines-based chemotherapy (52.5% vs. 76.7%; p<0.01) and more adjuvant chemotherapy with non-anthracyclines-based protocols (30% vs. 5.5%; p<0.01). Conclusion: In this study, we found management disparities between elderly and younger females with breast cancer. Elderly patients were undergoing to more axillary node dissection and less immediate breast reconstruction. Furthermore, 70 years old or older women received less neoadjuvant chemotherapy and anthracycline-based adjuvant therapy, even though there were no significant differences in clinical stage and elderly had higher incidence of positive axillary lymph node.
Relationship between tumor-associated macrophages in the tumor microenvironment as prognostic indicators in breast neoplasms
Authors: Amorim Fabline Ribeiro , Silva Mariana Cardoso , Diniz Julia Kalida , Labre Luciana Vieira Queiroz
Published: November 2024

Objective: This study aimed to correlate the presence of tumor-associated macrophages (TAMs) with clinicopathologic characteristics in 82 cases of breast cancer and assess their impact on tumours as possible prognostic markers. Methodology: Cases were selected among the records of anatomopathological examinations carried out at a reference center for cancer treatment. The inclusion criteria were histopathological diagnosis of invasive ductal carcinoma, immunohistochemical profile, clinicopathologic data available in the records, clinical follow-up for 5 years, and enough tumour tissue embedded in paraffin blocks to perform immunohistochemical analyses. For the statistical analyses, the cases were classified following a semiquantitative assessment of cell tagging as low infiltration or high infiltration and according to the mean value. Results: High levels of TAMs (CD68+) were significantly correlated with younger women, distant metastases, more advanced cancer staging, estrogen or progesterone receptors-negative, and triple-negative breast cancer (TNBC). The survival rate in cases of breast cancer with higher TAM infiltrate decreased, corroborating previous results. The number of CD68+ cells was a strong independent prognostic factor. Conclusion: Elevated levels of TAMs (CD68+) showed significant correlations with younger age groups, distant metastases, advanced cancer staging, negativity for estrogen or progesterone receptors, and TNBC. Survival rates were lower in breast cancer cases with increased TAM infiltration, consistent with earlier findings. The quantity of CD68+ cells emerged as a robust independent prognostic indicator.
Mammography in the Federal District: analysis of suspected and confirmed malignancy cases between 2018 and 2023
Authors: Bittar Mariana Valadares , Vieira Natália Barros Salgado , Lavor Bianca Santos Arrais de , Marra Gabriel de Assis , Esteves Paulo Lisbão de Carvalho
Published: November 2024

Objective: This study aimed to evaluate information related to mammograms classified as BI-RADS 4–6 in the Federal District over the past 5 years. Methodology: This is a retrospective study of descriptive and quantitative nature, utilizing secondary data collected from the Cancer Information System (SISCAN), available on the DATASUS electronic platform. The situation in the Federal District between 2018 and 2023 was analyzed, incorporating the following variables: quantity of mammograms, clinical indication, age range, type of screening, prior mammography, whether a physical examination had been previously conducted, BI-RADS classification, and the interval between request, collection, and results. Results: During the analyzed period, 2,806 mammograms resulting in BI-RADS 4–6 were performed, with the vast majority indicated for screening (76.8%) and predominantly in patients aged 50–60 years (37.4%). Regarding screening mammograms, a large proportion was allocated to the target population (81.7%), with the remainder for the high-risk population (11.5%) and patients already treated for breast cancer (6.6%). The majority of patients had previously undergone mammography (71.8%), and it was also predominant to perform a physical examination of the breasts before the examination was requested (90.5%). Category 4 of the BI-RADS classification was the most prevalent among the three (73.4%). The time between request and examination was also verified, with more than half of the mammograms performed within 10 days (60.6%), and the time between examination and result, with almost half also being released within 10 days (49.3%). Conclusion: The commendable performance in both access to and execution of mammograms as a preventive strategy in the Federal District is noteworthy. Mammography proves to be an excellent screening method, demonstrating its usefulness for early detection and appropriate follow-up of breast cancer.
Is it possible that there is a relationship between meningioma and the appearance of breast cancer? A systematic review
Authors: Andrade Gustavo Moreira , Milhomens Isabela Alves , Pinheiro Giovana Netto , Ramos Gustavo Nunes , Silva Giovana Martins da , Milki Marcos Vinícius , Montanini Júlia França
Published: November 2024

Objective: This study aimed to verify whether there is a relationship between the appearance of breast cancer in patients previously diagnosed with meningioma. If this relationship is found, this research will also aim to encourage other research to understand the reason for this relationship. Methodology: We comprehensively searched the PubMed database for case reports and case series that included the incidence of meningioma and patients with the diagnosis of breast cancer in their papers. Our systematic review followed the PRISMA statement guidelines Results: There are more than 49 reported and dated cases of the association between meningioma and breast cancer. Therefore, it is clear that there is an implicit association between meningiomas and breast carcinoma when we look at these data. Many of these cases occur during pregnancy, which can lead to a hormonal hypothesis in their genesis. In a bidirectional study, 795,000 patients were observed who had follow-up for years, in which the standardized incidence ratio was 1.27 for meningioma after a case of breast cancer; in 28,000 patients, the standardized incidence ratio was 1.32 for breast cancer after meningioma. However, in a mono-institutionalized study, 12,330 patients were analyzed and only 33 were observed to have meningioma, presenting a low relational value. Conclusion: It was observed that there is an inconsistency between the numerous clinical cases found and the research carried out, so there is no way to conclude the correlation between the tumors, but we cannot discard these data. Therefore, further research must be carried out so that we can further improve screening against these tumors; however, from this review, it is now possible to think of meningioma as a differential diagnosis for neurological symptoms in patients with breast cancer or a previous history.
Evaluation of HER2-low incidence in the clinical oncology service of Hospital das Clínicas da Universidade Federal de Goiás
Authors: Toledo Fernanda José de , Rosa Victor Domingos Lisita , Araujo Neto Augusto Rodrigues de , Queiroz Polido Larissa Vieira de , Mendanha Adriane Borges de Andrade , Alves Ravena Figueiredo , Quinan Paulo Victor Monteiro , Gabriel Augusto Ribeiro
Published: November 2024

Objective: The objective of this study was to determine the incidence and epidemiology of patients with Human Epidermal Growth Factor Receptor-type 2 (HER2-low) breast cancer in the oncology service of the HC-UFG from March 2022 to February 2023. Methodology: This is an observational and cross-sectional study, which included patients diagnosed with invasive breast cancer and excluded those with immunohistochemistry HER2 3+, HER2 0, or HER2 2+ with positive fluorescent in situ hybridization (FISH) by immunohistochemistry and those under 18 years old. Results: HER2-low tumors at HC-UFG are predominantly luminal (82%). Sixteen patients (11.2%) from the HER2-low group were eligible for analysis and epidemiological characterization, concluding that the average age was 60.2 years, the majority were female (93.7%), had a performance status of 0 at diagnosis (75%), and had a ductal histological subtype (93.7%). Regarding risk factors, 75% had a positive family history of cancer, 37.5% were smokers, and 43.7% were obese, with none being alcohol consumers. Some expression of HER2 was identified in a total of 17 immunohistochemistry tests, thereby classified as HER2-low (14.08%). This proportion of patients, previously classified as triple-negative or luminal, received a new classification, making them also eligible for new drugs available for this specific group. Conclusion: From February 2022 to March 2023, HER2-low incidence in breast cancer patients at HC-UFG corresponded to 14.08%. A higher frequency was observed in patients with a positive family history of cancer.
Analysis of radiological findings in treated breast cancer patients who had mammography in the state of Tocantins in 2023
Authors: Paz Cândida Verônica de Andrade , Duarte Ianny Keruly Damião Pessoa , Santos Eduarda Martins dos , Viana Karoline Nunes Rodrigues , Silva Jascyone Barbosa da , Camargo Rafael Pereira , Nascimento Tássia Aimê Teixeira , Anjos Fabiana Cândida Queiroz Santos
Published: November 2024

Objective: This study aimed to evaluate the results obtained in mammography in 2023 in women above 30 years old who previously had breast cancer treatment in the state of Tocantins. Methodology: This is a quantitative and comparative study of mammography results in treated breast cancer patients. It reunited data from the Cancer Information System (SISCAN/DATASUS) using biological sex, time, and location of the exam as filters, evaluating new radiological findings. Results: In 2023, 229 mammographies were done in women above 30 years of age who previously had breast cancer. It was analyzed according to the Breast Imaging Reporting and Data System (BI-RADS). It was observed an expressive number of BI-RADS 2 with a prevalence of 86.89%, followed by 8.73% represented by BI-RADS 0 and 3.05% Bi-RADS 4. The categories BI-RADS 1, 3, and 5 presented the same percentage with only 0.43%. The age group with the highest number of radiological findings was between 60 and 64 years old, which constitutes 46 exams of the total studied; this number had 37 classified as Bi-RADS 2, 3 as BI-RADS 4, and 1 as BI-RADS 5. The last one was the only finding of the sample that is in this category, which represents 1.74% of the sample with suspect lesions. Conclusion: Screening the more considered risk population than usual is necessary in the face of the current prevalence of radiological findings. However, data analysis shows a bigger concern among women between 60 and 64 years old, as there was a recurrence of highly suspect findings only in this age group in 2023.
Breast cancer treatment delays in Brazil: an ecological study from 2017 to 2022
Authors: Antonini Marcelo , Freitas Sofia Naira Barbosa , Mattar Andre , Pinheiro Denise Joffily Pereira da Costa , Amorim Andressa Gonçalves , Teixeira Marina Diógenes , Ferraro Odair , Lopes Reginaldo Guedes Coelho
Published: November 2024

Objective: This study aimed to evaluate the delay from diagnosis to treatment initiation for breast cancer in Brazil between 2017 and 2022, investigating the relationship between treatment delay, type of treatment, and cancer stage, alongside annual trends in the initiation times of treatment. Methodology: Utilizing a descriptive observational design, the research analyzed data from the Brazilian Unified Health System’s Oncology Panel (DATASUS). The study encompassed female breast cancer cases across Brazil, focusing on the interval to treatment start, cancer stage, and treatment type. Statistical analyses included chi-square tests and joinpoint regression to discern temporal trends, measuring changes through annual percent change (APC). Results: From 237,073 cases identified, 24.4% began treatment within 30 days, whereas 37.2% experienced delays beyond 91 days. Radiotherapy showed the longest wait times, with notable delays across all treatment types (p <0.001). Early-stage patients had longer wait times compared with advanced stages (p <0.001). The trend analysis indicated a decrease in patients starting treatment after more than 121 days, but a concerning reduction in those commencing within 30 days (APC -1.15), and an increase in delays of 61–91 days (APC 4.03). Conclusion: The majority of Brazilian women faced substantial treatment initiation delays, with the most pronounced in radiotherapy and among early-stage patients. The trend analysis highlighted an increase in treatment delays, suggesting an urgent need to address these issues to improve the timeliness of breast cancer care in Brazil.
Contribution Of Parental And Teachers' Guidance Towards Independent Behavior Of Elementary School Children
Authors: Br Sembiring Vidiani , Ndona Yakobus , Gultom Ibrahim
Published: November 2024

The contribution of parental and teacher guidance to the independent behavior of elementary school children needs to be considered carefully. Although this guidance plays an important role in child development, overprotective attitudes, lack of consistency, and the influence of the social and technological environment can hinder children's independence. This study uses the library research method. The data collection technique in this study was carried out through documentation review or document review. To ensure the validity of the data in this study, the source triangulation technique was used. The results of the study showed that 1). The Role of Parents in Shaping the Independence of Elementary School Children is to play an important role in shaping children's independence, with democratic parenting patterns proven to be more effective in encouraging independence than authoritarian or permissive parenting patterns. 2). The Role of Teachers in Developing the Independence of Elementary School Children is to develop student independence through a teaching approach that encourages responsibility and active participation. By giving individual and group assignments, and involving students in projects and class discussions, teachers help students learn independently. 3). Collaboration of Parents and Teachers in Developing Independence of Elementary School Children is that parents and teachers play an important role in supporting the development of independence of elementary school children. Open communication and good cooperation between the two parties ensure that children receive consistent guidance, both at home and at school.
Shifting Domestic Roles In The Household And Their Influence On Children's Education In Matang Sagoe Village Peusangan Sub-District Bireuen District
Authors: Hasanah Uswatun , Mardhiah Ainal , Hayati Hayati , Zubaidah Zubaidah , Nurbayani Nurbayani
Published: November 2024

The shift in domestic roles in Matang Sagoe indicates a shift towards a more equal division of responsibilities between husband and wife. This has various impacts on children's education . Some Matang Sagoe people still hold fast to traditional values, where mothers are expected to remain the main caregivers and managers of the household, while fathers are the main breadwinners. This study uses a qualitative method with a field research approach. Data collection techniques consist of in-depth interviews, participatory observation and documentation. The results of the study show that 1). The form of shifting domestic roles in households on children's education in Matang Sagoe Village Peusangan Sub-District Bireuen District is from traditional roles to more flexible roles, working mothers and a more equal division of tasks. 2). The influence of shifting domestic roles in households on children's education in Matang Sagoe Village Peusangan Sub-District Bireuen District is on increasing father involvement in children's education, the role of working mothers and their influence, higher child independence and the negative influence of limited time. 3). Factors of shifting domestic roles in households on children's education in Matang Sagoe Village Peusangan Sub-District Bireuen District are economic changes, education levels and cultural and social influences
The Affect of Physical Parameters on Flood Potential in the Upstream River and the Musi Watershed of Kepahiang, Indonesia
Authors: Supiyati  , Elisa Imania , Halauddin
Published: November 2024

Fllod often occur if the rainfall is high, the flood-affected areas are downstream areas around the Musi Watershed of Kepahiang. The purpose of the study was to find out the characteristics of the physical parameters that affect the potential for flooding in the upstream river and the Musi Watershed. The method used are in situ measurement and laboratory analysis. The results of research, the characteristics of the river's physical parameters after the rain, the river flow discharge is 14.50 m3/s, floating sediment discharge 1.13 kg/s, bottom sediment discharge 43 x 10-4 kg/s, and total sediment discharge 113 x 10-2 kg/s. While the condition is not raining, the river flow discharge is 5.37 m3/s, the floating sediment discharge is 0.30 kg/s, the bottom sediment discharge is 32 x 10-4 kg/s, and the total sediment discharge is 30 x 10-2 kg/s. The dominant sediment texture is sand, clay and silt with a grain size of 1.4 mm - 600 µm. The river bathymetry has a lower elevation at the confluence of the Gegasan River and Lanang River which causes the river currents to reverse, if there is an increase in rainfall it will cause flooding in the area around the river.
Development of Digital Learning Materials Using a QR Code Based Book Creator Application to Improve Student Learning Outcomes in Science Subjects
Authors: Widanti Adima Putri , Fathurrahman Moh.
Published: November 2024

This research aims to develop digital learning material using the QR Code-based Book Creator application to improve learning outcomes in science, especially on human digestive system material. This research uses the ADDIE development model. The results showed that the use of digital learning material using the QR Code-based Book Creator application was able to improve student learning outcomes as evidenced by an increase in the gain value of 0.39 in small groups and 0.54 in large groups with moderate categories. In addition, this digital learning material is also considered very feasible by experts with a feasibility score of 98.60% from media experts and 93% from material experts. Positive responses also came from teacher with a response questionnaire score of 95% and a student response score of 93.30% with very feasible criteria for use in learning the human digestive system. Based on these results, the digital learning material developed not only improves student learning outcomes on human digestive system material but the learning material is very feasible to use.
Website-Based Learning Media Using Google Sites to Improve Student Learning Outcomes in Natural and Social Sciences Subjects on Biodiversity Material
Authors: Nasution Fadilah Nur Jannah , Astuti Tri
Published: November 2024

Inappropriate use of learning media in learning process activities can cause uninteresting learning. This study aims to develop website-based learning media using Google Sites in the Natural and social sciences subject biodiversity material in grade V elementary school. The research method used is Research and Development with the ADDIE development model. The subjects in this study were media experts, material, teachers, and 21 fifth-grade elementary school students. Data collection is used in the form of test techniques and non-test techniques. The test techniques used are pretest and posttest, while non-test techniques include observation, interviews, questionnaires, and documentation. In the data analysis process, the normality test, t-test, and N-Gain test methods were used, which were carried out with SPSS 23 software. The results of the study presented a validation test by media experts getting a score of 91%, while the validation test by material experts got a score of 92%, with a very feasible category. The t-test results on the small group trial presented a sig. (2-tailed) of 0.008. while in the large group trial, the t-test presents a sig value (2-tailed) of 0.000. The results of the N-Gain Test in the small group and large group trials showed an increase in value of 0.60 and 0.55 which was in the medium category. This shows an average increase between pretest and posttest scores. From these results, it is concluded that website-based learning media using Google Sites is very feasible and effective in improving student learning outcomes related to the biodiversity material in grade V elementary school.
The Effect of Implementation Socio-Scientific Issue Approach in the Context of Controversial Environmental Issues on Students' HOTS (Higher Order Thinking Skills)
Authors: Auliah Army , Djangi Jasri , Fadly Dewiyanti
Published: November 2024

This research aims to see the influence of the SSI approach in the context of controversial environmental issues on chemistry students' HOTS abilities. The research method used was quasi-experimental with a post-test-only control group design. The research subjects were 26 students in class A of the chemistry education study program as the control class and 21 students in the ICP class of the chemistry education study program as the experimental class. The instruments used are observation sheets and test questions that measure students' HOTS abilities. The results of this study show that the average post-test score of the experimental class using the SSI approach was 80.15, while the average score of the control class was 60.5. The t-test shows that this difference is statistically significant with a p-value of 1.122 x 10-5, well below the 0.05 significance level. Because the p-value obtained is much smaller than 0.05, we can reject the null hypothesis (H0), which states that there is no significant difference between the two groups. These results indicate that the SSI approach in the context of controversial environmental issues has a positive influence on chemistry students' HOTS abilities in electrochemical concepts.
Isolation and Inhibitory Activity Testing of Alpha-Glucosidase Enzyme from Endophytic Bacteria in Kumis Kucing (Orthosiphon aristatus (Blume) Miq.) Leaves
Authors: Putri Indah Tamara Herman , Rustini  , Ismed Friardi , Sardi Valdy F , Arifah Nurwahidatul
Published: November 2024

Orthosiphon aristatus (Blume) Miq., commonly known as kumis kucing, is frequently used in traditional Indonesian medicine to treat diabetes, hypertension, rheumatism, gout, and as a diuretic. However, large-scale production of medicinal products from natural sources requires significant raw material and land, creating a need for alternative methods. This study explores the potential of isolating endophytic bacteria from kumis kucing leaves to serve as α-glucosidase enzyme inhibitors, offering a more sustainable approach. Eight bacterial endophytes were isolated and tested using bioautography assays and IC50 measurements to assess their inhibitory activity. Four isolates—KK 1, KK 3, KK 4, and KK 5—demonstrated significant α-glucosidase inhibition, with IC50 values of 41.35 µg/mL, 57.04 µg/mL, 56.70 µg/mL, and 164.16 µg/mL, respectively. Molecular testing identified KK 1 as Priestia aryabhattai, while KK 3 and KK 5 were identified as Priestia megaterium. These findings suggest that endophytic bacteria isolated from Orthosiphon aristatus leaves have the potential to be developed as natural sources of α-glucosidase inhibitors, which are beneficial for diabetes management.
Pendekatan Arsitektur Tropis pada Perancangan Rumah Susun di Kawasan Kumuh Kampung Karanganyar Yogyakarta
Authors: Haris Abel Fahreza , Indriani Ni Ketut Ayu Intan Putri Mentari , Gazalba Zaedar , Putra Pascaghana Jayatri , Raissilki Muhammad Iqbal , Bachtiar Jasmine Chanifah Hanifah Uzdah , Handayani Teti
Published: November 2024

Pendekatan arsitektur tropis merupakan pendekatan desain yang paling relevan dalam merancang bangunan di iklim tropis. Hal tersebut berkaitan dengan prinsip-prinsip arsitektur tropis yang berupaya untuk mampu beradaptasi dan merespon kondisi cuaca dan iklim. Dengan begitu, ruangan pada bangunan akan kebih nyaman dan sehat karena dirancang sesuai dengan konteks dan kondisi iklim sekitarnya. Tujuan dari tulisan ini adalah untuk merumuskan solusi terkait permukiman kumuh padat penduduk di perkotaan dengan merancang rumah susun yang ideal untuk masyarakat menggunakan pendekatan arsitektur tropis. Metode yang digunakan dalam penyusunan tulisan ini yaitu melakukan pemetaan potensi dan masalah serta melakukan studi literatur dan kajian terkait prinsip arsitektur tropis. Dengan menerapkan prinsip – prinsip arsitektur tropis, rumah susun diharapkan akan menjadi tempat hunian yang nyaman dan sehat untuk masyarakat sekaligus menyelesaikan masalah permukiman kumuh di perkotaan.
Pendekatan Arsitektur Hijau pada Perancangan Youth Creative Art Center di KEK Mandalika
Authors: Putri Baiq Adisty Tahira , Saptaningtyas Rini Srikus , Anantama Aldhi Nugraha , Gazalba Zaedar , Kamase Giska Ayu Pradana P , Wardi Liza Hani Saroya , Puji Lale Garjita Kusumaring
Published: November 2024

Arsitektur hijau merupakan salah satu konsep yang cenderung memanfaatkan sumber daya alam dibanding sumber daya buatan. Hal ini menjadi acuan bagi pribadi terkait dengan kesadaran jika terus menerus menggunakan sumber energi buatan yang berdampak bagi manusia ataupun bangunan itu sendiri. Konsep arsitektur hijau kuat kaitannya dengan berkelanjutan. Berkelanjutan yang dimaksud yaitu adanya pengurangan pemakaian energi yang tidak dapat diperbarui agar tidak cepat habis pakai. Tujuan dari tulisan ini adalah merumuskan solusi untuk mengurangi dampak negatif pembangunan terhadap lingkungan, mengembangkan dan memajukan generasi pemuda, pegiat seni, serta kebutuhan sarana pariwisata pada KEK Mandalika yang berskala internasional. Metode yang digunakan dalam penyusunan tulisan ini yaitu melakukan identifikasi potensi dan masalah serta melakukan studi literatur dan kajian terkait prinsip arsitektur hijau. Dengan menerapkan prinsip – prinsip arsitektur hijau, bangunan pusat seni Youth Creative Art Center diharapkan akan menjadi fasilitas dan sarana terpusat yang dapat menampung atau mewadahi segala jenis kegiatan kesenian dan budaya, baik di dalam negeri maupun luar negeri.
Entre Clarices e Cristinas: Gênero e Deficiência como Marcadores de Exclusão Social
Authors:   , Silva Anderson Douglas da
Published: November 2024

O presente trabalho explora a interseccionalidade entre deficiência e marcadores sociais de gênero por meio do estudo de caso de Cristina Silva Mendonça, uma mulher de 36 anos, oriunda de Nova Londrina-PR, residente em Maringá-PR. Com uma família de cinco irmãos, dos quais dois possuem deficiências visual e uma transtorno no desenvolvimento, Cristina é estudante de Licenciatura em Música pela Unicesumar e atua como servidora pública e cantora. As informações foram coletadas por meio de entrevistas realizadas presencialmente, utilizando o aplicativo URec, em quatro momentos distintos entre dezembro de 2022 e março de 2023. Este estudo emprega uma abordagem qualitativa para analisar como as experiências da servidora pública, como mulher, pessoa com deficiência na família e profissional no campo da música interagem com os marcadores sociais, destacando-se a importância do gênero e da deficiência no contexto das ciências sociais. O referencial teórico ancorou-se em estudos sobre feminismo interseccional e sociologia da deficiência, explorando como essas categorias operam simultaneamente na configuração das experiências sociais e profissionais de Cristina. Os resultados indicam que a deficiência, quando cruzada com o gênero, pode ampliar as barreiras enfrentadas por mulheres no mercado de trabalho e na sociedade em geral. Observou-se que as responsabilidades da servidora pública e cantora como cuidadora em sua família afetam sua vida profissional e pessoal, refletindo a persistência de estereótipos de gênero e a necessidade de políticas públicas mais eficazes para a inclusão de pessoas com deficiências e o apoio às mulheres que se encontram nesse contexto. Este caso exemplifica a complexidade dos marcadores sociais e enfatiza a necessidade de uma análise mais aprofundada e sensível a essas interseções nas ciências sociais.
E-book Manejo Odontológico em Crianças Surdas: Adaptações e Estratégias para um Manejo Odontológico Eficaz
Authors: Aquino Flávia Garcia de , Rodrigues Evellyn de Cássia Martins , Alves Juliana Garcia , Valente Raissa Baia , Lopes Thiago Pereira , Oliveira Gyselle Ribeiro de Carvalho , Proença Aline Costa Flexa Ribeiro de
Published: November 2024

O ebook “Manejo Odontológico em Crianças Surdas: Adaptações e Estratégias para um Manejo Odontológico Eficaz” é uma iniciativa poderosa e necessária tanto para acadêmicos quanto para profissionais da área odontológica. Esse material oferece a oportunidade de desenvolver e divulgar conhecimentos específicos que promovem um atendimento inclusivo, acolhedor e eficiente para crianças com deficiência auditiva. A proposta se destaca pela sua relevância em termos de inclusão e aprimoramento da prática odontológica, beneficiando tanto os profissionais quanto os pacientes. Desse modo, o e-book aborda adaptações permitidas no ambiente odontológico . Para atender crianças de forma eficaz, o consultório deve ser um espaço visualmente acessível, com materiais e sinalizações que facilitem a comunicação. Essas adaptações vão além da estrutura física; inclui também a preparação do profissional para interpretar sinais de desconforto e entender as reações das crianças, que muitas vezes são expressas visualmente ou por meio de gestos. Em seguida, o material foca em estratégias de comunicação essenciais para que uma criança surda se sinta compreendida e acolhida. Técnicas como o uso da Língua Brasileira de Sinais (Libras), leitura labial, projeções visuais, e até o uso de imagens e materiais gráficos são cruciais para estabelecer uma comunicação clara e confiável. O ebook oferece um guia prático para que os profissionais possam se comunicar com a criança de forma eficaz, diminuindo barreiras e fortalecendo o vínculo de confiança. Outro ponto abordado é o manejo comportamental adequado às necessidades desse público. Crianças surdas podem sentir mais ansiedade em um ambiente odontológico, especialmente se a comunicação com o profissional for limitada. O ebook sugere técnicas comportamentais para minimizar o estresse, promover a cooperação e criar um ambiente acolhedor, contribuindo para uma experiência mais positiva e tranquila para a criança e sua família. Além disso, o ebook inclui orientações para pais e cuidadores , destacando a importância de uma rotina de higiene bucal em casa. Esse conteúdo é fundamental para que a criança tenha um cuidado integral, complementando o trabalho feito no consultório. Com conhecimento e estratégias adaptadas, é possível proporcionar uma saúde bucal acessível e digna, promovendo uma odontologia que valoriza o respeito e o acolhimento.
EXPERIMENTAL IN-PLANE COMPRESSION TEST OF BRICK MASONRY WALLS WITH REINFORCEMENT RATIO
Authors:   Faculty of Engineering, University of kufa, Najaf, Iraq, Al-Wazni Saad , Mahdi Waseem ,   Faculty of Engineering, University of kufa, Najaf, Iraq, Zainul-Abideen Ahmed ,   Faculty of Engineering, University of kufa, Najaf, Iraq
Published: November 2024

Perforated clay brick masonry is a popular and widely used construction, offering both structural and aesthetic benefits. The structural behavior of perforated clay brick masonry walls is a significant topic in the field of civil engineering. However, understanding the compressive and tensile strength of these walls are influenced by various factors such as the quality of mortar joints, the distribution of mortar, and the presence of reinforcement. The purpose of this study is to investigate the compressive behavior of four perforated clay brick masonry walls, using cement-sand mortar, with two different systems under in-plane compression load. The first masonry system is unreinforced with filling joints, and the other system is reinforced by steel bars embedded in the mortar as a low reinforcement ratio. The study provided valuable arguments about how mortar distribution affects wall performance, which is significantly impacted by poor quality of head joints and the fully or partially distributed mortar in the masonry joints. Also, the role of low reinforcement ratio within the construction industry has important effect. The mentioned parameters are investigated through practical case studies demonstrating their effects in the context of ductility and ultimate load capacity. It was found that the compressive strength of the unreinforced masonry system is highly increased to the distribution of the mortar by 35 % and 133% for filling all holes in brick units and the head joints, respectively, due to increasing the bonding between brick units in the masonry wall specimen. In the reinforced masonry system, the utilization of a low reinforcement ratio is increased the ultimate load capacity by 60% and decreased the ultimate displacement by 54%., but it is no longer provided significant changes to the ductility.
TORQUE RIPPLE RATE REDUCTION OF 6/4 SWITCHED RELUCTANCE MOTOR USING SLIDING MODE LEARNING CONTROLS
Authors:   Department of electronics and communication engineering, university of Kufa, Kufa, Iraq, Razaq Mohammed Zahraa , Shehab Hadi Abdal-Razak ,   Department of electrical engineering, university of Kufa, Kufa, Iraq
Published: November 2024

This paper presents a sliding mode control for reducing the torque ripple of a 6/4 switched reluctance motor. Several types of sliding mode control based on the current variable are implemented: conventional sliding mode control, learning sliding mode control, and learning sliding mode control with PID. The research also includes the design of the controller and simulation results that demonstrate the effectiveness of the proposed method in reducing torque ripple. The learning sliding mode control with PID has a significant implication for reduction torque ripple rate improvement of about 70% compared to the conventional model. As well as controlling the speed response and settling time. This makes the control of switched reluctance motors a current and speed controller.
A NEW NESTED HYBRID DWT-HD-SVD WATERMARKING SCHEME FOR DIGITAL IMAGES
Authors:   Department of Computer Engineering/College of Engineering/Mustansiriyah University, Baghdad, Iraq, R. Qasim Sara , KALIFA ABBOUD Maryam ,   College of Electrical Engineering Technical/Middle Technical University, Baghdad, Iraq, Hassony Jaddoua Eman ,   Computer Engineering Department/Ministry of Culture, Baghdad, Iraq
Published: November 2024

Digital watermarking encrypts private information with the original data to protect the ownership rights of the digital asset. This paper suggests a brand-new nested watermarking technique (two-level watermarking technique) to protect copyrights of digital images. It based on a hybrid discrete wave transformation-Hessenberg decomposition-Singular value decomposition (DWT-HD-SVD). The gray-watermark image is first split into n parts, and each portion goes through two steps of watermarking, using two host images, using hybrid DWT-HD-SVD method and one final level of encryption (based on the Lightweight algorithm, the high-speed cryptographic method). The results of the simulation reveal that the suggested system offers a high level of imperceptibility, reliability and robustness. Also it can be used for both the colored and the grayed images.
A REVIEW OF CONTROL METHODS FOR QUADROTOR UAV
Authors:   Department of Electrical Engineering, Faculty of Engineering, University of Kufa, Iraq, Najaf, Iraq, Al-Husnawy Thamer , Al-Ghanimi Ali ,   Department of Electrical Engineering, Faculty of Engineering, University of Kufa, Iraq, Najaf, Iraq
Published: November 2024

This study reviews numerous control approaches utilized to address various issues encountered by unmanned aerial vehicles (UAVs). Specifically, focusing on the quadrotor system. Due to its versatility and compact size, quadrotors have gained popularity as UAVs in recent decades. Quadrotors face challenges such as ambient disturbances, impediments, non-parametric and parametric perturbations while performing tasks. Consequently, a robust and efficient control system is essential for such a system to ensure the stability and enhance their performance. It should be noted that, in this review, we have examined and analyzed the most recent highly cited papers selected from esteemed journals and magazines renowned for their exceptional quality and reputation.
CLOUD-SMART SURVEILLANCE: ENHANCING ANOMALY DETECTION IN VIDEO STREAMS WITH DF-CONVLSTM-BASED VAE-GAN
Authors:   PG and Research Department of Computer Science, Providence College for Women (Autonomous), Coonoor, The Nilgiris, H Sivalingan
Published: November 2024

Anomaly detection in computer vision is crucial, and manual identification of irregularities in videos is resource-intensive. Autonomous systems are essential for efficiently analysing and detecting anomalies in diverse video datasets. Video surveillance relies heavily on anomaly detection for monitoring equipment states through time-series data. Presently, deep learning methods, particularly those based on Generative Adversarial Networks (GAN), have gained prominence in time-series anomaly detection. This paper proposes a novel solution: the double-flow convolutional Long Short-Term Memory (DF-ConvLSTM) - based Variational Autoencoder- Generative Adversarial Network (VAE-GAN) method. By co-training the encoder, generator, and discriminator, this approach leverages the encoder's mapping skills and the discriminator's discrimination capabilities simultaneously. The proposed strategy is compared with LSTM-VAE, LSTM-VAE-Attention, and VAE. The proposed method is evaluated using metrics for recall, accuracy, precision, and F1 score. With classification accuracies of 91% on the University of Central Florida (UCF) crime dataset, the experimental results outperformed alternative techniques. Furthermore, the analysis of the ROC curve revealed that the suggested method performed better than the others, as evidenced by its higher ROC (Receiver Operating Characteristic) values. Experimental results demonstrate the proposed method's ability to rapidly and accurately detect anomalies in surveillance videos, ensuring efficient and reliable anomaly detection. Experimental results show the method's rapid, accurate anomaly detection in surveillance videos, ensuring efficiency and reliability. However, challenges include high computational costs, affecting the practicality of implementation for real-time anomaly detection.
THE EFFECT OF SBR LATEX AND WARM MIX AGENT ON THE PERFORMANCE OF DRY AND WET ASPHALT MIXTURES
Authors:   Department of Civil Engineering, University of Benghazi, Benghazi, Libya, Eltwati Ahmed , M.B. alkhadar Bubaker ,   Department of Civil Engineering, University of Benghazi, Benghazi, Libya., Abbas Haider ,   Department of Civil Engineering, University of Babylon, Babylon, Iraq., Enieb Mahmoud ,   Department of Civil Engineering, Assiut University, Assiut 71516, Egypt, Abbas Al-Jumaili Mohammed ,   Department of Civil Engineering, University of Kufa, Iraq.
Published: November 2024

Moisture damage has been identified as one of the most common causes of distress in asphalt mixes. The attachment between bitumen aggregate components deteriorates when water interacts at the interface, causing the binder to be stripped from the exterior of the aggregate and cohesive breakdown inside the asphalt binder. To reduce the moisture sensitivity of asphalt mixes, styrene-butadiene rubber (SBR) and antistripping warm mix additive (WMA) have been frequently utilized. Nevertheless, the application of SBR and WMA as a compound modifier has yet to be investigated thus this research aims to evaluate the influence of SBR and WMA i.e., ZycoTherm on the moisture resistance of asphalt mixtures. For this reason, several tests, including modified Lottman, resilient modulus, and dynamic creep, were used to assess the mechanical properties of the mixes in both wet and dry situations. The results found that the SBR improved the mechanical performance of the mixture in dry conditions, whereas using the ZycoTherm as a single modifier was more effective in improving the performance of the mix in dry conditions. However, the application of the compound modifier (SBR and ZycoTherm) could optimize the performance of asphalt mixtures in both conditions i.e., dry and wet.
Developing video-conferenced English speaking test (VEST) for classroom-based assessment in tertiary education
Authors: Imamyartha David , Bilqis Mutiara , Hudori Rizki Febri Andika , Puspa Areta , Wahjuningsih Eka
Published: November 2024

A proper speaking test may pose challenges to teachers due to suboptimal assessment literacy and the laborious administration of a speaking test. Technology can help alleviate the labor while enabling teachers to ascertain the accuracy and validity of the speaking test. In this direction, this study aims to develop a videoconferenced English-speaking test (henceforth VEST) with the aid of videoconferencing technology. Aligned with the empirics on the use of technology for speaking assessment, this study addresses the gapping void in how videoconferencing technology can be harnessed to escalate the practicality and positive impacts of a classroom-based speaking test in an Indonesian EFL setting. The development adhered to the ADDIE framework involving Analysis, Design, Development, Implementation, and Evaluation. The test prototype was evaluated using a test usefulness analysis framework. The evaluation results were coupled with reflection results of test takersâ€™ experiences to guide test revision. Given the small sample size, this study has unveiled the potential of VEST to improve the praxis of speaking assessment and the resultant test takersâ€™ experience. Implications and recommendations for future studies are also discussed.