bluuebunny/crossref_metadata_2025 huggingface dataset:
Intensive care unit delirium in patients with severe COVID-19
Authors: Smith Ryan J. , Lachner Christian , Singh Vijay P. , Cartin-Ceba Rodrigo
Published: June 2022

Background:

Delirium is common in patients with severe coronavirus disease-19 (COVID-19). The purpose of our study was to determine whether severe COVID-19 is an independent risk factor for the development of delirium in patients treated in the intensive care unit (ICU).

Methods:

This prospective observational cohort study involved 162 critically ill patients admitted to a multidisciplinary ICU during 2019 and 2020. A validated screening tool was used to diagnose delirium. Multiple delirium risk factors were collected daily including clinical characteristics, hospital course, lab values, vital signs, surgical exposure, drug exposure, and COVID-19 characteristics. After univariate analysis, a multivariate logistic regression analysis was performed to determine independent risk factors associated with the development of delirium.

Results:

In our study population, 50 (31%) patients developed delirium. A total of 39 (24.1%) tested positive for COVID-19. Initial analysis showed COVID-19 to be more prevalent in those patients that developed delirium (40% vs. 17%; P = 0.003). Multivariate analysis showed opioid use (odds ratio [OR]: 24 [95% confidence intervals (CI): 16–27]; P ≤ 0.001), benzodiazepine use (OR: 23 [95% CI: 16–63] P = 0.001), and estimated mortality based on acute physiology and chronic health evaluation IV score (OR: 1.04 [95% CI: 1.01–1.07] P = 0.002) to be independently associated with delirium development. COVID-19 (OR: 1.44 [95% CI: 0.13–10.6]; P = 0.7) was not found to be associated with delirium.

Conclusion:

Delirium is prevalent in critically ill patients admitted to the ICU, including those with COVID-19. However, after adjustment for important covariates, we found in this cohort that COVID-19 was not an independent risk factor for delirium.
Evaluation of Clinical and Biochemical Parameters of Trinidadian Patients with Coronary Artery Disease for Predicting the Revascularization Strategy
Authors: Monplaisir Tamika Kachada , Nayak Shivananda B , Bhaktha Geetha , Ali Ronan , Mohan Surapaneni Krishna , Ambrose Jenifer Mallavarapu
Published: June 2022

Background:

In recent times, optimal revascularization approaches have been used for treating multi-vessel obstructive coronary artery disease (CAD) patients. Based on the disease severity, making the decision to perform a suitable revascularization intervention in the patients is of paramount importance.

Aim:

This study aimed to evaluate the biochemical parameters of patients with suspected CAD in Trinidad and assess their clinical significance for predicting revascularization strategy.

Materials and Methods:

One hundred and twenty-four patients referred for angiography were recruited for the study. Biochemical parameters such as fasting blood sugar (FBS), lipid profile, cardiac enzymes, creatinine, uric acid, N-terminal probrain natriuretic peptide (NT-proBNP), soluble ST2, interleukin 6, and hemoglobin A1C (HbA1c) were explored. Similarly, we examined clinical parameters such as age, the presence of chronic conditions, and ethnicity.

Results:

With respect to revascularization strategies, FBS, NT-proBNP, HbA1c, and soluble ST2 correlated moderately with coronary artery bypass grafting (CABG) by Point-Biserial correlations: FBS-r = 0.196, P = 0.029, NT-proBNP-r = 0.208, P = 0.020, soluble ST2-r = 0.178, P = 0.048, and HbA1c-r = 0.282, P = 0.001. The presence of Type 2 diabetes (T2D) at baseline and ethnicity also formed statistically significant associations with CABG-ethnicity (χ2 (1) =7.267, P = 0.007) and T2D at baseline (χ2 (1) =12.858, P < 0.001).

Conclusion:

Ethnicity and presence of T2D were also significantly associated with both CAD severity and revascularization decision-making and should be taken into consideration for further study. Further investigation of these parameters might prove to be useful to predict the revascularization strategy required for treating CAD patients.
Moderator Band Calcification Masquerading Infrahisian Conduction System Disease
Authors: Das Debasish , Das Tutan , Pramanik Subhas , Bannerjee Anindya , Kumar Abhinav
Published: June 2022

Relationship between moderator band (MB) calcification and infrahisian conduction system disease has not been described in the world literature so far. We report a case of a 74-year old male presenting with recurrent cardiogenic syncope 6 times is the last 2 months. He had echocardiographic evidence of dense moderator band calcification. Electrophysiology study revealed a His-Ventricular(HV) interval of 100 msec suggestive of significant infrahisian conduction system disease. He was put on a dual chamber pacemaker and he had no further episode of syncope during the follow up. Our description is unique and the first in the world literature that dense MB calcification in echocardiography may be an indirect clue to the presence of severe infrahisian conduction system disease.
A Rare Cause of Facial Asymmetry
Authors: Günes Yasin Celal , Ciliz Deniz Sozmen , Cetin Hüseyin
Published: June 2022

The hemifacial lipomatosis (HL) is an extremely rare pathology that results in partial hemifacial hypertrophy. This case report presents a 16-year-old male patient who underwent surgery for swelling in the right hemifacial region 11 years ago and then presented to our hospital with a diagnosis of recurrent HL in the same area.
Polarization and deformations of generalized dendriform algebras
Authors: Ospel Cyrille , Panaite Florin , Vanhaecke Pol
Published: June 2022

We generalize three results of M. Aguiar on Loday’s dendriform algebras to dendriform algebras associated with algebras satisfying any given set of relations. We adapt the concept of polarization to such algebras, and use it to generalize Aguiar’s results on deformations and filtrations of dendriform algebras. We introduce weak Rota–Baxter operators and use them to prove a generalization of another result by Aguiar, which provides an interpretation of the natural relation between infinitesimal bialgebras and pre-Lie algebras in terms of dendriform algebras.
Evolution of SARS-CoV-2 variants: a mini-review
Authors: Musa-Booth T.O. , Adegboro B. , Medugu N.
Published: June 2022

SARS-CoV-2 has evolved over time with several mutations, especially on the spike protein, which has led to emergence of various variants. With the evolution of SARS-CoV-2 come new challenges in surveillance, effectiveness of preventive and treatment strategies, and outcome of the disease.  Despite the lockdowns, mask mandates and other preventive measures put in place, in addition to over 10 million vaccine doses that have been  administered globally as of February 2022, COVID-19 cases have risen to over 435 million and resulted in over 5.9 million deaths, largely as a result  of the evolution of SARS-CoV-2 variants. To review the evolution of these variants, we searched different online database sources using keywords  such as “source of SARS-CoV-2”, “SARS-CoV-2 origin”, “evolution of SARS-CoV-2”, “SARS-CoV-2 variants”, “variants of concern”, “variants of interest”,  and “variants of high consequence”. This was to enable us give a good report about the various variants of SARS-CoV-2 that have emerged so far,  and the public health challenges posed by them.
Assessment of microbial quality and detection of extended spectrum β-lactamase genes in Gram-negative bacterial isolates of herbal mixtures commonly hawked in Sagamu metropolis, Ogun State, Nigeria
Authors: Olaniran O.B. , Ajayi S.E. , Oluwatobi O.B. , Adeleke O.E.
Published: June 2022

Background: The use of herbal mixtures in the treatment of diseases is on the rise. Many of these herbal drugs are not produced under hygienic conditions and safety issues associated with herbal medicines may have an exacerbated impact in immunocompromised and elderly individuals. This study aimed to determine the microbial loads of locally prepared herbal mixtures and detect extended spectrum beta-lactamase (ESBL) genes  in any isolated Gram-negative bacteria pathogen.

Methodology: Fifty local herbal mixtures were purchased randomly from three locations in Sagamu town (Sagamu market, Ita-Oba Road and Isale  Oko) in Ogun State, Nigeria. The mean total viable bacterial (MTVB), mean total coliform (MTC), and mean total fungal (MTF) counts were  determined by the plate count method. The bacterial isolates were streaked on differential bacteriological media while the fungi isolates were  grown on potato dextrose agar. The isolates were identified upon growth on culture media using conventional biochemical tests. Antibiotic  susceptibility pattern of the isolates was determined using Kirby-Bauer disk diffusion technique. Phenotypic detection of ESBL was done by the  modified double disc synergy test followed by amplification detection of blaTEM, blaCTX-M and blaSHV genes with polymerase chain reaction (PCR)  assay.

Results: Bacteria and fungi were isolated from 38 (76.0%) and 25 (50.0%) of the herbal samples respectively. Ten (20.0%) and 14 (28.0%) of the  samples had mean bacterial and fungal load that exceeded 105CFU/mL or g, respectively. Nineteen (38.0%) of the herbal samples analyzed had total  coliforms. Fifty-one isolates belonging to eight bacterial genera and 28 fungi isolates belonging to four fungal genera were obtained. Thirty-  two (62.7%) of the bacterial isolates were Gram-negative while 19 (37.3%) isolates were Gram-positive. Staphylococcus aureus was the most  common bacterial isolate (33.3%) while Aspergillus species was the most prevalent fungus (60.7%). Sixteen (84.2%) S. aureus and 26 (81.3%) Gram- negative isolates were multidrug resistant, and 6 (18.8%) of 32 Gram-negative isolates were ESBL producers. ESBL-encoding genes were detected in  7 (27%) of the 26 multidrug resistant Gram-negative bacteria with TEM and SHV being the most prevalent 4 (14.8%) while CTX-M was identified in  only one isolate.

Conclusion: This study reported the presence of microbial contaminants which exceeded the safety limits of 105 CFU/g according  to World Health Organization. The use of locally prepared herbal medicines poses a major health risk due to the lack of microbial quality standards.
Investigation of rodent reservoirs of emerging pathogens in Côte d'Ivoire, West Africa
Authors: Meite S. , Koffi K.S. , Kouassi K.S. , Coulibaly K.J. , Koffi K.E. , Sylla A. , Sylla Y. , Faye-Ketté H. , Dosso M.
Published: June 2022

Background: One of the main health problems in West Africa remains upsurge of emerging pathogens. Ebola virus disease outbreak occurred in 2014 in Liberia, Guinea and Sierra Leone, Monkeypox virus in Nigeria in 2017 and most recently Lassa virus in Nigeria, Togo and Benin in 2018.  These pathogens have animal reservoirs as vectors for transmission. Proper investigation of the pathogens in their rodent vectors could help  reduce and manage their emergence and spread.

Methodology: This study was conducted with an approval from the Côte d’Ivoire Bioethics Community. Small mammal trappings were carried out in  9 sites within three zones namely, peri-urban, peri-rural and protected areas. Liver, lung and kidney tissues from trapped small mammals were  sampled in accordance with the recommended conditions of biosafety and bioethics. The organs were transported in liquid nitrogen to the  laboratory. Molecular tests were used to detect pathogens. Orthopoxviruses and Monkeypox virus were detected in the organs by PCR using  consensus primers targeting the virus surface membrane haemagglutinin (HA) genes, while Leptospira species were detected by PCR using primers  targeting the rrs and lfb1 genes.

Results: Out of 4930 night-traps, 256 (5.19%) small mammals were trapped including Crocidura, Rattus, Lophuromys, Praomys, Mus and Mastomys.  Leptospira species were detected in 6 genera from 7 study sites and the infected small mammals accounted for 13.3%. Leptospira sp was detected  mainly in the rodent vector genera Rattus (32.3%), Lophuromys (29.0%), and Praomys (16.1%). Three species of Leptospira were detected and  Leptospira interrogans was the most common frequent species (74.2%). Monkeypox virus was not detected from studied small mammals.

Conclusion: The initial data from our investigation indicates the presence of Leptospira sp in rodent vectors, Rattus, Lophuromys and Praomys,  which are the potential small mammalian reservoirs of this pathogen in Cote d’Ivoire.
Biosafety, Antioxidant and Antidiarrhoeal Potentials of Afzelia africana Seed n-Hexane Extract
Authors: Ndukwe G. I. , Okhiku J. O. , Obomanu F. G. , Benjamin G. O.
Published: June 2022

This study evaluated the biosafety, phytochemicals, antioxidant activity, acute toxicological profile and antidiarrhoeal property of n-hexane extract of Afzelia africana seeds. Results from the phytochemical profiling (using gas chromatography - mass spectrometry technique) elicited the presence of hexadecanoic acid (34.97 %), 9, 12, 15-octadecatrien-1-ol (16.27%) and oleic acid (6.71%) as major compounds associated with antioxidant and antidiarrhoeal effects. The study revealed that A. africana seed possesses antioxidant potentials across four models at 100 𝜇g/ml (39.6%, 59.6%, 48.11% and 0.765 for 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging, ferrous ion chelating, hydrogen peroxide scavenging, and reducing power assays respectively). No adverse effect or lethality was recorded at ≤5000 mg of extract per kg body weight of tested animals after 14 days observation. In castor oil induced diarrhoea, a significant (p<0.05) increase in delayed onset of stooling and percentage inhibition (up to 92.4%) with decrease in defecation frequency were observed across the treated groups when compared with the control. Similarly, the extract showed a significant (p<0.05) dose dependent decrease in gastrointestinal motility with increase in percentage inhibition (up to 91.9%) in charcoal meal test. In conclusion, Afzelia africana seed antidiarrhoeal property has been validated and its folklore benefit affirmed by this study.
Development and Evaluation of Acoustic Sound Absorption Composite from Orange Peels Residues and Sachet Water Bags
Authors: Saleh A.
Published: June 2022

The goal of this study was produce a device that would reduce the unwanted sound/noise produced by machines encountered in our daily activities using orange peels (agricultural residues) and sachet water bags. These materials were prepared, mixed in 70:30 % ratio and transferred into a two-roll mill (compounding machine), where they were melted at about 150oC temperature before transferring them to a compressing machine that was set at a lower temperature of 130oC. The composite panel was coupled together to form a box where three speakers were connected to MP3 and inserted into the box. Test was carried out to check for the sound absorption levels of the composite using a sound level meter. Results obtained show that ‘A’ weighing filter covers the full frequency range of 0–90 kHz before coupling the absorption box. This could irreversibly damage the auditory system since it fell outside the acceptable range of 0–80 dB frequency sensitivity of human ear. However, the sound level becomes within the acceptable frequency when coupled to the developed absorption box indicating that the composite board using orange peels and empty water sachet is a good sound absorber.
Ameliorative Effects of Aqueous Extract of Brassica nigra on Phenylhydrazine-Induced Liver Toxicity in Wistar Rats
Authors: Obayuwana E. , Obayuwana M. O.
Published: June 2022

Brassica nigra has been reported to possess antioxidant activity, anti-inflammatory activity, anti-epileptic activity, antidiabetic activity, anthelminthic activity, nephroprotective activity and hepatoprotective activity. In experimental models, phenylhydrazine been used to cause reproductive toxicity, nephrotoxicity, hepatotoxicity, hyperbilirubinemia and haemolytic anaemia. This study therefore aimed to investigate the effects of B. nigra on phenylhydrazine-induced liver toxicity through analysis of liver enzymes and histoarchitecture of the liver. Thirty (30) adult Wistar rats weighing between 180 and 200 grams were utilized in this investigation. They were bred in the Animal House of the Department of Anatomy, University of Benin, and were randomly assigned into six (6) groups of five (5) animals. Group A received 1 ml distilled water, Group B received phenylhydrazine only, Group C received phenylhydrazine and 0.1 ml of oxaliplatin, Group D received phenylhydrazine and 150 mg/kg body weight of B. nigra, Group E received phenylhydrazine and 300 mg/kg body weight of B. nigra while Group received phenylhydrazine and 600 mg/kg body weight of B. nigra. The study lasted for a period of eight (8) weeks. Significant elevations (P<0.05) in the mean concentrations of liver enzymes (ALP, AST, ALT) and total protein were recorded after the administration of phenylhydrazine while the treatment with different concentrations of B. nigra induced a reversal in those parameters to levels comparable with the control. In conclusion, B. nigra administration lowers a number of the harmful effects of in vivo phenylhydrazine administration in the liver of Wistar rats, according to the findings in this study.
Assessment of Charcoal Production and Its Impact on Deforestation and Environment in Borgu Local Government Area of Niger State, Nigeria
Authors: Adeniji O. A. , Ibrahim A. O. , Joshua D. A. , Fingesi U. I. , Osaguona P. O. , Ajibade A. J. , Akinbowale A. S. , Olaifa O. P.
Published: June 2022

Commercial charcoal production is gradually becoming one of the major sources of sustenance and currently plays a major role in promoting entrepreneurial development in Borgu Local Government Area of Niger State. The study was carried out to assess charcoal production and its impact on deforestation and environment in the study area. Data for the study were generated from a structured questionnaire administered to charcoal producers in the study area. Data obtained revealed that majority (83%) were male with 56% within the age class of 21-40, majority (67%) were married and about (51%) attained primary education. Majority of the producers (82%) used traditional earth mound kiln method for charcoal production and about 56% of the producers obtained their raw material from free area. Most preferred tree species for charcoal production was Prosopis africana and accounted for 61%. Loss of biodiversity ranked 1st as regards impact of charcoal production on deforestation and environment in the study area, closely followed by forest degradation and soil degradation respectively. This study will enable forestry policy makers, charcoal producers, and farmers in the study area to be better informed about the implications of charcoal production on deforestation and environment and seek innovative means and ways to combat its menace.
Chemo-Protective Effects of Dl-Limonene Unaided and in-Blend with 6-Methyleneandrosta-1, 4-Diene-3, 17-Dione on N-Nitroso-N-Methylurea and Estrogen Sulfotransferase Breast Cancer-Induced Albino Female Rat
Authors: Ojedapo G. C. , Minari J. B. , Oloyede A. M.
Published: June 2022

Breast cancer is a serious prime hassle commonly diagnosed in women worldwide and it is currently the leading cause of cancer-related mortality. In N-nitroso-N-methylurea (NMU) and estrogen sulfotransferase (EST) breast cancer-induced female rat, the study evaluates the chemo-protective possibilities of DL-limonene (1:1) and its combination with 6-Methyleneandrosta-1, 4, Diene- 3, 17-Dione using standard techniques. Amongst others, data obtained reveals mild areas of clogged blood vessels and pulmonary inflammation revealed in the histopathology section. Interestingly, it's possible that DL-limonene alone at a concentration of 10% could be an effective breast cancer treatment. The findings also revealed that combining DL-limonene with 6-ADD at 5% and 12.5mg/kg could reduce the risk of toxicity associated with higher chemotherapeutic dosages in long-term treatment. Furthermore, at a modest dose, this combination may increase the use of aromatase inhibitors in premenopausal women. Despite the medicinal and therapeutic benefits of DL-limonene, it is best to take it in moderation due to its possible harmful effects on the blood vessels.
Prediction of Liquid Accumulation in Gas Wells to Forecast the Critical Flowrate and the Loading Status of Individual Wells
Authors: Joseph A. , Bassey I.
Published: June 2022

Liquid accumulation is a major problem in gas wells. The inability of gas to lift coproduced liquids to the surface imposes back pressure on the reservoir, limits the ultimate recovery and ultimately kills the well if improperly managed. Therefore, accurate prediction of its occurrence and reliable monitoring strategy is key to effectively handling liquid accumulation in gas wells. In this study, machine learning algorithms were used to develop regression and classification models to accurately predict the critical flowrate and the loading status of individual wells. The regression models used are the feed-forward neural network and a least squares support vector machine models while the decision trees model was used as the classification model to characterize the loading status of the wells investigated. These models were validated using actual published data and it was observed that the feed-forward neural network performed better in predicting the critical rate compared to the least squares support vector machine model with an R2 value of 0.9833, and thus was adopted. The feed-forward neural network model was further compared with other critical rate models; and a consistent result with least percent error of 5.571% was also observed.  Form this study, it is obvious that the neural network model provide benefits and good prospects in investigating liquid loading phenomena in gas wells compared to empirical models that apply so many simplifying assumptions.
Availability and Co-Substrate Potential of Typha latifolia for Biogas Production in Funtua, Katsina State, Nigeria
Authors: Yusuf S. S. , Muhammad I. , Jibrin A. , Olaleru F. , Aminu U. I. , Ahmed A. , Salim A. A. , Lawal N. , Hassan M. M.
Published: June 2022

In order to reduce global warming through fossil fuel utilization, biogas production from biodegradable biomass seems a sustainable alternative. This study evaluated the availability and co-substrate potential of T. latifolia for biogas production in Funtua, Katsina State Nigeria. A purposive sampling technique was used in selecting the wards that were used for this study. A 1204 metres transect was used for 32 quadrats; 19 of these were laid on the 953m contiguous land area at intervals of 50m; 9 quadrats covered 450m, 5 quadrats were on 250m, 3 on 153m, and 2 on 100m. The remaining 13 transects were laid on the 251m un-contiguous patches. Coordinates of various potentials sites were recorded using Global positioning system. There were an average of 27 T. latifolia stands per m2. A total of 32,388 of T. latifolia stands were recorded in the study area; Dukke ward (23,968), Makera (8,205) and Maska 216. T. latifolia is available in lqrge quantities, and a potential co substrate in anaerobic digestion for biogas production in Funtua. It is recommended that the study should be replicated in time later to establish a trend of the T. latifolia species in terms of population.
Scientific Foundations of State and Law
Authors: Vladlenov Denis
Published: June 2022

All rights reserved. Printed in the United States of America. No part of this publication may be reproduced, distributed, or transmitted, in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher. The content and reliability of the articles are the responsibility of the authors. When using and borrowing materials reference to the publication is required. Collection of scientific articles published is the scientific and practical publication, which contains scientific articles of students, graduate students, Candidates and Doctors of Sciences, research workers and practitioners from Europe and Ukraine. The articles contain the study, reflecting the processes and changes in the structure of modern science.
“A MORTE PEDE CARONA”: Klebsiella pneumoniae COMO AGRAVANTE NA INFECÇÃO POR Strongyloides stercoralis
Authors: Moreno Brenda de S. , Nascimento Letícia de A. , Azevedo Pedro Ricardo G. , Brandão Fabiana
Published: June 2022

Introdução: Durante o ciclo evolutivo alguns helmintos realizam Ciclo de Loss, fenômeno que pode estar relacionado a um intrigante mecanismo de “carona” translocando bactérias intestinais para o pulmão. Neste contexto, há a associação entre Gram-negativa Klebsiella pneumoniae e o parasito nematódeo Strongyloides stercoralis, um evento mais comum que o documentado. K. pneumoniae está “intimamente” relacionada a elevadas taxas de sepse neonatal, infecção intestinal. Por outro lado, o geohelminto S. stercoralis causa a verminose com maior fator de risco para imunocomprometidos. Objetivo: Discutir a interação entre patógenos de domínios distintos, que quando presentes no mesmo hospedeiro agravam o desfecho clínico. Metodologia: Trata-se de uma revisão integrativa baseada no modelo PRISMA, evidenciando aspectos como epidemiologia, fatores de virulência e resistência, bem como relatos de casos de co-infecção entre S. stercoralis e K. pneumoniae. Resultado: A análise dos dados sugere que a translocação intestinal bacteriana é agravante em casos de estrongiloidíase, relacionada a quadros graves de coinfecções. Estudos apontam K. pneumoniae como uma das principais bactérias intestinais realocada por S. stercoralis. Considerações finais: São escassas as fontes de inquérito da coinfecção por esses organismos, o que pode prejudicar a interpretação dos desfechos clínicos, do controle e  vigilância, além de limitar abordagens terapêuticas mais eficientes.
Polar research in the conditions of climate change (Part 1. XVI century – the beginning of XX century)
Authors: Докучаев А.Я. , Лобанов К.В. , Гурбанов А.Г. , Кулаков Ф.В. , Курдюков Е.Б. , Чичеров М.В. , Мясников А.В.
Published: June 2022

В Рудно-петрографическом музее ИГЕМ РАН хранятся документы и геологическиеколлекции, связанные с именами Э.В. Толля, Ф.П. Литке, А.В. Колчака, Ф.Н. Чернышёва, О.О. Ба-клунда, Р.Л. Самойло́вича, Л.М. Старокáдомского, С.В. Обручева и многих других выдающихся уче-ных, исследовавших архипелаг Шпицберген, арктические районы России (побережье, острова) иакватории морей Северного Ледовитого океана (СЛО). Экспедиции в ранее не исследованные рай-оны Арктики преследовали не только научные цели: они были направлены также на расширениеграниц российских владений и практическое освоение Северного морского пути.Русская Полярная экспедиция (РПЭ, 1900–1902 гг.), Гидрографическая экспедиция Северного Ледо-витого океана (ГЭСЛО, 1910–1915 гг.), многие другие экспедиции в приполярные области СЛО доначала XX века проходили, как правило, в чрезвычайно неблагоприятных погодных условиях, иногдас человеческими жертвами.В статье рассмотрен вопрос об изменениях климата, повлиявших на проведение полярных экс-педиций по изучению и освоению Северного Ледовитого океана и побережья российской Арктики,до начала XX века.

The Ore-Petrographic Museum of the IGEM RAS contains documents and geologicalcollections associated with the names of E.V. Toll, F.P. Litke, A.V. Kolchak, F.N. Chernyshev, O.O.Backlund, R.L. Samoilovich, L.M. Starokadomsky, S.V. Obruchev and many other outstanding scientistswho explored the Svalbard archipelago, the Arctic regions Russia (coast, islands) and the waters of theArctic Ocean seas (SLO). Expeditions to previously unexplored areas of the Arctic pursued not onlyscientifi c goals: they were also aimed at expanding the borders of Russian possessions and practicaldevelopment of the Northern Sea Route.Until the beginning of the 20th century the Russian Polar Expedition (RPE, 1900–1902), the HydrographicExpedition of the Arctic Ocean (HEAO, 1910–1915), many other expeditions to the subpolar regions ofthe Arctic Ocean, as a rule, took place in extremely unfavorable weather conditions, sometimes withhuman casualties.The article considers the issue of climate change that infl uenced the conduct of polar expeditions to studyand develop the Arctic Ocean and the coast of the Russian Arctic until the beginning of the 20th century.
The Tliy necropolis is a reference monument of the ancient history of the Caucasus
Authors: Чшиев В.Т.
Published: June 2022

В статье рассматриваются археологические материалы Тлийского некро-поля – эталонного памятника южной группы центрального варианта кобанской культу-ры Кавказа на фоне новых артефактов Адайдонского могильника.

The article examines the archaeological materials of the Tliy necropolis – the referencemonument of the southern group of the central variant of the Koban culture of the Caucasusagainst the background of new artifacts of the Adaydon burial ground.
A Structural Dynamics Modification Strategy based on Expanded Squeal Operational Deflection Shapes
Authors:   SD Tools, Martin Guillaume , Balmes Etienne ,   SDTools, Chancelier Thierry ,   Hitachi Astemo, Thouviot Sylvain ,   Hitachi Astemo, Lemarie Rémi ,   Hitachi Astemo
Published: June 2022

"To analyse brake squeal, measurements are performed to extract the Operational Deflection Shape (ODS) characteristic of the limit cycle. The advantage of this strategy is that the real system behaviour is captured, but measurements suffer from a low spatial distribution and hidden surfaces, so that interpretation is sometimes difficult. It is even more difficult to propose system modifications from test alone. Historical Structural Dynamics Modification (SDM) techniques need mass normalized shapes which is not available from an ODS measurement. Furthermore, it is very difficult to translate mass, damping or stiffness modification between sensors into physical modifications of the real system. On the model side, FEM methodology gives access to fine geometric details, continuous field over the whole system. Simple simulation of the impact of modifications is possible, one typical strategy for squeal being to avoid unstable poles. Nevertheless, to ensure accurate predictions, test/FEM correlation must be checked and model updating may be necessary despite high cost and absence of guarantee on results. To combine both strategies, expansion techniques seek to estimate the ODS on all FEM DOF using a multi-objective optimization combining test and model errors. The high number of sensors compensates for modelling errors and while allowing imperfect test. The Minimum Dynamics Residual Expansion method used here, ensures that the complex ODS expanded shapes are close enough to the measured motion but have smooth, physically representative, stress field, which is mandatory for further analysis. From the ODS expansion, the two underlying real shapes are mass-orthonormalized and stiffness-orthogonalized using the model resulting in a reduced model with two modes known on the full model. Sensitivity analysis is thus possible and the impact of thickness modifications on frequencies is built. This provides a novel structural modification strategy where the parameters are thickness distributions, and the objective is to separate the frequencies associated with the two shapes found by expansion of the experimental ODS. The methodology will be illustrated for a recent disk brake test and model. "
Challenges that criminal law faces due to innovative activity development
Authors: Некрасов В.Н.
Published: June 2022

В статье рассматриваются сущность, содержание и направления изменений, вызванных достижениями науки и техники; особенности современного внедрения результатов инновационной деятельности в общественную жизнь; проблемы уголовно-правового регулирования общественных отношений, связанных с достижениями науки и техники. Автор приходит к выводу о том, что в современных условиях, связанных с динамичным развитием инновационной деятельности в целом и отельных ее направлений, законодателю следует выработать устойчивые принципы и модели, восполняющие неизбежно появляющиеся пробелы в уголовном законодательстве. Одним из возможных способов обеспечения оперативности принимаемых решений, соблюдения принципа неотвратимости ответственности является допустимость применения аналогии уголовного закона

The article examines the essence, content and directions of changes caused by advances in science and technology; features of modern implementation of innovative activity results of in public life; problems of criminal law regulation of © Некрасов В. Н., 2022 86 IUS PUBLICUM ET PRIVATUM public relations related to achievements of science and technology. The author comes to the conclusion that in modern conditions associated with the dynamic development of innovation activity in general and its certain areas, the legislator should develop sustainable principles and models that fill the inevitably emerging gaps in criminal legislation. One of the possible ways to ensure the promptness of decisions taken and comply with the principle of inevitable responsibility is the permissibility to apply analogy in the criminal law
Problems to Implement the Humanism Principle in Sanctions of the Norms of the Special Part of the Criminal Code of the Russian Federatio
Authors: Простосердов М.А.
Published: June 2022

В статье подробно исследуются проблемы реализации принципа гуманизма при конструировании санкций уголовно-правовых норм Особенной части действующего уголовного закона Российской Федерации. Объектом рассмотрения выступают общественные отношения, регулирующие установление конкретных видов и наказаний в конкретных их пределах за совершение конкретных преступлений. Предметом являются нормы действующего уголовного закона Российской Федерации. Автор изучает конструкции санкций норм Особенной части уголовного закона в контексте реализации гуманистических положений Общей части Уголовного кодекса Российской Федерации и приходит к выводу о несовершенстве конструкций некоторых уголовно-правовых санкций, которые препятствуют реализации принципа гуманизма. В заключении автор формулирует теоретические основы конструирования санкций норм Особенной части Уголовного кодекса Российской Федерации, способствующие реализации принципа гуманизма

The author examines problems of implementing the principle of humanism in the construction of sanctions of criminal law norms of the special part of the current criminal law of the Russian Federation. The object of the study is public relations regulating establishment of specific types and punishments within their specific limits for commission of specific crimes. The subject of the study is norms of the current criminal law of the Russian Federation. The author studies constructions of sanctions of the norms of the Special Part of the Criminal Code of the Russian Federation in the context of the implementation of the humanistic provisions of the General Part of the Criminal Code of the Russian Federation. The article identifies imperfection of the structures of some criminal sanctions that prevent realization of the principle of humanism. The author proposes theoretical foundations for constructing sanctions of the norms of the Special Part of the Criminal Code of the Russian Federation, contributing to the implementation of the principle of humanism.
Insuficiencia Renal Crónica en pacientes de Hemodiálisis con Covid-19
Authors: Alcocer Betty Sarabia , Sarabia Betty Mónica Velázquez , Rodriguez Pedro Gerbacio Canul , Canché Baldemar Aké , Gutiérrez Tomás Joel López , Gamboa Carmen Cecilia Lara , Balan Román Pérez , Canché Gonzalo Abdiel Canul
Published: June 2022

En este artículo se presentan los resultados de una investigación que se llevó a cabo en la Universidad Autónoma de Campeche-Facultad de Medicina en el que se desarrolló un estudio observacional, descriptivo, transversal y prospectivo para la identificación de cualquier enfermedad que sea factor de riesgo para presentar Enfermedad Renal Crónica en los pacientes  que acudieron a sesiones de hemodiálisis y que presentaron algún síntoma de COVID-19, las variables analizadas en los pacientes  fueron la edad de inicio de hemodiálisis, género y factores asociados que precipitaron la aparición de Insuficiencia Renal Crónica y por consiguiente el uso de hemodiálisis como terapia sustitutiva. Los resultados mostraron que los pacientes tuvieron diversos factores de riesgo que han presentado desde hace mucho tiempo atrás, que nos habla de la importancia del adecuado control y tratamiento de enfermedades para prevenir complicaciones de la Insuficiencia Renal Crónica y tratamiento sustitutivo diálisis.
IR, UV and CV studies of Schiff base metal complexes derived from o-phenylinediamine with chlorobenzaldehyde
Authors: Nazeer M
Published: June 2022

A new N2 type Schiff base ligand was prepared by the condensation of o-phenylenediamine with p-chlorobenzaldehyde. The ligand and its mixed-ligand complexes have been characterized by microanalytical data, molar conductance, magnetic susceptibility, IR, UV-Vis., spectra.  The data show that they have composition of the type [ML(ox)]Cl2 where M = Cu(II) and Zn(II). The UV-Vis. and magnetic susceptibility data of all these complexes have adopted square-planar geometry around the central metal ion. Moreover, these complexes have higher electrolytic nature confirmed by the molar conductance data. Furthermore, their magnetic susceptibility values provide evidence for the monomeric nature. From the cyclic voltammetric data, both complexes reveal that these complexes are quasi-reversible.
AWARD ACCEPTANCE SPEECHES: LINGUOSTYLISTIC FEATURES
Authors: Harutyunyan Kristine
Published: June 2022

The present paper investigates linguostylistic features peculiar to celebrities’ award receiving speeches - a public  discourse variety of modern English which is popular not only for its social importance but also  for its linguistic and stylistic significance. The results of the analyses carried out on the basis of linguostylistic and case study methodology show that emotional colouring and expressiveness are the most typical characteristics of award acceptance speeches. The impact on the listener or reader is achieved through the usage of different literary-stylistic devices. The award receiving speeches also make a strong emotional impact on the listener during celebrations and through them, while the length (conciseness or wordiness) does not minimize the strong influence on the audience.
SPACE AND TIME TRANSFERENCE OF MAIN CHARACTERS IN BRITISH AND ARMENIAN FAIRY TALES
Authors: Mkhitaryan Yelena , Madatyan Lusine
Published: June 2022

The paper presents a comparative study of space and time transference of main characters in British and Armenian fairy tales, with pointing out convergent and divergent features of expressing these notions in a folkloristic text. The analysis shows that similarities prevail over differences.  In both British and Armenian fairy tales spatial transference takes priority over the temporal one, when the main characters’ adventures or heroic deeds are presented; temporal transference is more common when evil deeds are described, especially the ones that happen at night. Besides, tragic and evil events are likely to take place more in enclosed areas than in open places.  The numbers three and seven occurring in British and Armenian fairy tales have the same symbolic meanings. The differences concern the numerical indication of time points usually observed in British fairy tales and the presentation of the narrative space, which is somewhat different in view of the diverse country landscape of England and Armenia. While the opening formulas are almost identical, the closing formulas in Armenian tales reveal some differences, ending with a reward for the listener and teller of the fairy tale as well as with blessings and behests directed to the listener.
Evaluation of Aqueous and Ethanolic Extracts of Garcinia Kola on Testicular Morphology of Adult Male Wistar Rats'
Authors:   Department of Human Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences Abia State University, Uturu, Nigeria, N. N. Chukwudi-Emelike
Published: June 2022

Despite its medicinal value, bitter kola is known as a prayer nut, and traditional lifestyle has brought us much food, such as "chewing of bitter kola and its resources." Thirty-five male Wistar rats weighing between 160. to 200.g were divided into seven groups based on weight similarity. For 21 days, Group A was the control and was given only rat meal and water ad libitum, Group B (LDAEG) and C (HDAEG) were given500mg/kg and 1000mg/kg of G. kola aqueous extract, Group D (LDEEG) and E (HDEEG) were given500mg/kg and 1000mg/kgof G. kola ethanolic extract, and Group F (LDAEEG) and G (HDAEEG) were co-treated with 500mg/kg and 1000mg/kg of G. kola aqueous and ethanolic extracts respectively. The rats were weighed and sacrificed on day 21, and their testes were harvested and fixed for histological studies. SPSS version 23 was used to analyse the data, and each group's mean and standard deviation were calculated. Our findings show that the experimental group had a considerable rise in body weight above the control group. The histological results of the testes showed normal features in the control group and mild inactive seminiferous tubules in the test groups. According to our findings, bitter kola has no negative effects on the Wistar rats' testes, especially when taken in low doses.
Facilitating EFL Students’ Development of Speaking Skills through Cue Card Media
Authors:   Postgraduate Program, Universitas Negeri Gorontalo, Indonesia, Rahmayanti Firma Dewi
Published: June 2022

This paper aims to investigate the use of Cue Card Media to facilitate the improvement in the English speaking competence through storytelling based on the recount text at the grade 10 students of SMK 1 public vocational high school using Cue Card Media. This Classroom Action Research employed four main stages by Kemmis and McTaggart’s (2014) model, including planning, action, observation, and reflection. The present proposed CAR study was undertaken at the SMK 1 public vocational high school Gorontalo as the site for this study, with the grade ten students majoring the program stream of travel business or Usaha Perjalanan Wisata (henceforth UPW) being the subject of this study. The data in this research were collected by using several instruments, to include checklist observation, questionnaire, and speaking test. Further, the analysis reports of this CAR study relied heavily upon the qualitative interpretation, whilst quantitative served to strengthen the qualitative data interpretations. The results found that the application of the Cue Card successfully enhanced students’ speaking skills by 26.28% statistically, with 55.56% in the first cycle and 81.84% in the second cycle. Following the open-ended survey questionnaires, it appeared that due to the efficacy of Cue Cards, these attractive speaking media benefitted students when it comes to speaking performance activities, yet the drawbacks of Cue Card learning media in speaking were also recognized. Discussions as to how Cue Cards may develop the practice of speaking instruction were also provided. This study adds to the growing pool of literature on the Cue Card implementation in the teaching of speaking skills in English.
Motivation of Achievement as a Medium Variable in the Correlation among Technical Skill, Work Environment and Educational Staff Members Service Quality at Faculty of Teacher Training and Education Lambung Mangkurat University Banjarmasin
Authors:   Master of Educational Administration Program, Lambung Mangkurat University, Banjarmasin 70123, Indonesia, Solekah Solekah
Published: June 2022

The importance of education personnel's service quality through instilling good technical skills in the faculty is crucial. It effects individual performance and total organizational performance and eventually has an impact on increasing service quality. Therefore, this study aims to analyze the direct and indirect correlation among technical skills, work environment, achievement motivation, and educational staff members service quality. This study employed a quantitative method with facto exposure. The participants in this study were 128 educational staff members from the Faculty of Teacher Training and Education from eleven sub-sections. Proportional random sampling was utilized as the sample method. With 98 participants, the number of samples was determined using the Slovin formula. Data was collected using a questionnaire consisting of technical skills (16 items), work environment (24 items), achievement motivation (32 items), and service quality (24 items). This research instrument was tested for the level of validity and reliability using the product moment correlation test person. The research data were analyzed using path analysis to see direct and indirect correlations between variables, by first conducting normality and linearity tests. The results showed that there was a direct and indirect correlation between technical skills, work environment and achievement motivation on service quality.
The Effect of Teacher Competence, Work Discipline and Work Motivation on Teacher Performance
Authors:   Master of Educational Administration Program, Lambung Mangkurat University, Banjarmasin 70123, Indonesia, Alimmudin Alimmudin
Published: June 2022

Performance is a work achievement or a person's work based on the quality achieved in carrying out the responsibilities received. Teacher performance is a determining factor in achieving educational goals. Factors that affect performance include: teacher competence, teacher work discipline and teacher work motivation. This study aims to determine and analyze the effect of teacher competence, teacher work discipline and teacher work motivation on performance. This research approach is quantitative. The population of this study was 180 people from 18 elementary schools. The sampling technique used is Proportional Random Sampling. The number of samples was determined based on the Sloving formula with 150 respondents. collecting data using a questionnaire consisting of teacher competence (14 items), work discipline (15 items), work motivation (8 items), teacher performance (16 items). This research instrument tested the level of validity and reliability using the product moment person correlation test. The research data were analyzed using path analysis to see the direct and indirect effects between variables, by first testing normality, linearity, and homogeneity. The results showed that there was a direct and indirect influence between the influence of teacher competence, work discipline and work motivation on teacher performance. The analysis of the research results used descriptive statistics, simple regression, path analysis and multiple regression using SPSS Window Version 25. The results showed that there was an influence between: (1) teacher competence on teacher performance of 0.871, (2) work discipline on teacher performance of 0.871. 0.991, (3) work motivation on teacher performance of 0.892, (4) teacher competence on work discipline of 0.882, (5) teacher competence on work motivation of 0.884, (6) teacher competency on teacher performance through work discipline of 0.874 ( 7) teacher competence on teacher performance through work motivation of 0.868. Based on the findings of this study, it can be suggested several things such as: (1) Teachers as educators should be more active in an effort to improve teacher performance, (2) Teachers in schools should increase discipline and motivation at work, (3) educational institutions should provide opportunities for teachers to develop themselves, (4) this research should be used as a reference and a reference for conducting research that is still related.