bluuebunny/crossref_metadata_2025 huggingface dataset:
APLIKASI PUPUK KANDANG SAPI DAN AIR LIMBAH LELE TERHADAP PERTUMBUHAN KELENGKENG (Dimocarpus longan L.) DI KEBUN BUAH AGROFORESTRI UNIVERSITAS LANCANG KUNING
Authors: Kusaini Nurul , Juliarti Anna
Published: January 2023

Longan (Dimocarpus Longan Lour) in the Unilak Agroforestry Orchard has the potential to be developed. The aim of this study was to analyze the effect of cow manure and catfish wastewater on the growth of longan. The study was conducted for 3 months, namely January-April 2022. The study design used factorial RAL with two factors, namely the dose of cow manure with 3 levels (control, 300 g, and 600 g) and catfish wastewater with 4 levels (control, 250 ml, 500 ml, and 750 ml). The variables measured were the increase in height, diameter, and width of the canopy. The results showed that giving a dose of 250 ml of catfish wastewater resulted in the greatest increase in height of 20.00 cm compared to 13.67 cm without giving catfish wastewater. Giving a dose of 300 gr cow manure resulted in the greatest height increase of 18.50 cm compared to 17.17 cm without cow manure. The control interaction of cow manure and catfish wastewater at a dose of 250 ml resulted in the greatest height increase of 23.67 cm compared to that without cow manure and catfish wastewater of 8.33 cm.
The instability of meaning in metapragmatic neologisms
Authors: Bridges Judith
Published: January 2023

In this response I address the discussion notes written in reply to my focus article, “Explaining -splain in digital discourse.” In the remarks from Andrea R. Leone-Pizzighella, Bárbara Marqueta Gracia, Chaim Noy, François Cooren, Barbara Fultner, and Ursula Lutzky and Robert Lawson, some common themes emerged regarding the instability of meanings, how we treat neologisms, and some research methods for understanding the equivocal nature of me­tapragmatic neologisms. My reply addresses these issues. With the intent to accomplish the sort of productive, interdisciplinary conversation that Language Under Discussion promotes, I hope my reflection and final contribution helps us better understand language and communication.
Iannis Xenakis's Lasting Legacy in Mathematics of Music
Authors: Amiot Emmanuel
Published: January 2023

As a composer and theorist, Iannis Xenakis has raised the level and quality of mathematics involved in music to unprecedented heights. He inspired generations of composers and also stimulated research and development in the theory of music. The present paper explores how influential some of his ideas have proved to be in numerous domains.
Iannis Xenakis Arche-tekton
Authors: Mihailescu Teofil
Published: January 2023

Engineer, composer, architect, theorist, mathematician and even astronomer, in all these hypostases Iannis Xenakis seems to be an arche-tekton in the first meaning of this Greek word - the (old) one who knows the secrets of making a Construction, be it music, architectural object, structure and/or idea, living the “dream of life” in the context of the only arts that do not make mimesis, architecture and music. Without presenting in itself the projects in which he has left its mark, the paper explores “the symphony of the dream of life” as Iannis Xenakis crystallized it through the filter of architecture. The symbolic participation in this “concert” brings to light an Iannis Xenakis in a constant attempt to rewrite in modernity and avant-garde, in mathematical key, the architecture, the music and the philosophy belonging of its Greek cultural matrix, exploring the halo of meanings of the triad kosmos-polis-oikos and their re-semantizations as he understood it in his times. The “symphony of the dream of life” as crystallized by Iannis Xenakis may reveal us that the Road is an infinitely more important goal than the finality in the journeys of architecture, music, and man on the scale of history and at the scale of a human life, as is the story of any arche-tekton, semper inter mundos, constantly questioning the boundaries of the kosmos, in any of the “real” realities or virtual realities would he and it coexist.
PENGARUH PERTUMBUHAN PENJUALAN, PERPUTARAN PIUTANG, PERPUTARAN PERSEDIAAN, UKURAN PERUSAHAAN DAN LEVERAGE TERHADAP PROFITABILITAS (STUDI PADA PERUSAHAAN SEKTOR MAKANAN DAN MINUMAN YANG TERDAFTAR DI BURSA EFEK INDONESIA)
Authors: Murthi Silvia Nur Krishna , Subaki, Ahmad , Sumardi Sumardi,
Published: January 2023

Abstract— This study aims to determine the effect of Sales Growth, Accounts Receivable Turnover, Inventory Turnover, Company Size and Leverage on Profitability of Food and Beverage Sector Companies listed on the Indonesia Stock Exchange (IDX). The type of data used is secondary or quantitative data. The variables studied were Sales Growth, Accounts Receivable Turnover, Inventory Turnover, Company Size and Leverage on Profitability. The sample used was 8 companies in the food and beverage sector listed on the Indonesia Stock Exchange (IDX) for the 2015-2019 period. Determination of sample selection using purposive sampling and data processing method using multiple linear regression analysis. The results showed that partially the sales growth variable, accounts receivable turnover, had no significant effect on the profitability variable (ROA), the inventory turnover variable and company size had a significant negative effect on the profitability variable (ROA). While the leverage variable (DER) has a positive and significant effect on the profitability variable (ROA). Simultaneously, the variables of sales growth, accounts receivable turnover, inventory turnover, company size and leverage (DER) have a significant and significant effect on the profitability (ROA) variable. The ability of the independent variable in explaining the dependent variable can be seen from the analysis of the coefficient of determination R2 of 0.359%. This means that only 35.9% profitability (ROA) which can be explained by the variables of sales growth, receivables turnover, inventory turnover, company size and leverage (DER). While the remaining 64.1% is explained by other variables that are not included in this study.

 Keywords: Accounts Receivable Turnover; Company Size; Inventory Turnover; Leverage; Sales Growth
PERSEPSI KEMUDAHAN, CUSTOMER RELATIONSHIP MANAGEMENT DAN KUALITAS LAYANAN TERHADAP LOYALITAS PELANGGAN E-WALLET MELALUI
Authors: Dirnaeni Desti , Handrijaningsih Lies , Mariani T.R Septi , Anisah Anisah
Published: January 2023

Abstract- The use of electronic money makes transactions practical, efficient and the recording of transactions is carried out automatically following the banking books. All these advantages become an attractiveness for people to use them in their daily transactions. This study aims to determine the effect of perception ease of use, customer relationship management and service quality on customer loyalty through customer satisfaction of DANA E-wallet users in Bekasi City. The population in this study were all active and passive users in using DANA, and the number of research samples was 100 respondents with path analysis as an analytical tool. The results showed that perceived convenience, customer relationship management and service quality had an effect on customer loyalty through customer satisfaction, either directly or indirectly. The most dominant variable on customer loyalty through customer satisfaction in this study is service quality.

Keywords: Customer Loyalty; Customer Satisfaction; E-wallet
PENGARUH KEBAJIKAN, INTEGRITAS, KOMPETENSI, DAN KUALITAS INFORMASI TERHADAP INTENSI MEMBELI PRODUK DI INSTAGRAM
Authors: Susilo Purnama Jaya , Laksmidewi Dwinita
Published: January 2023

Abstract - The Instagram application is currently a popular application for selling products, including fashion products, by young people in Indonesia society. This study aims to examine the effect of perceived benevolence or the perception that stores on Instagram do good things, the integrity or honesty of stores, the competence, and the quality of the information provided by stores on Instagram, on purchase intentions. The research was conducted using a survey method, with consumer respondents who shop online for fashion products on Instagram. Hypothesis testing using mediation test with SPSS macros. The results show that perceived benevolence, integrity, and competence have a positive effect on purchase intention and are significantly mediated by consumer trust.

Keywords: Perceived Benevolence; Integrity; Competence; Quality of Information; Trust; Instagram
PERILAKU PENGGUNAAN “QRIS BRI BRIMO” PADA PEDAGANG SEBAGAI ALAT TRANSAKSI PEMBAYARAN DIGITAL
Authors: Wibowo Praditya , Rimadias Santi
Published: January 2023

Abstract- This study aims to analyze the behavior of using "QRIS BRI BRIMO" at merchants as a means of digital payment transactions in Indonesia. This study uses a descriptive research design approach with empirical data collected through an online survey of 100 merchants who adopt "QRIS BRI BRIMO" as a means of digital payment transactions. Data was collected using an online questionnaire from May to August 2022. Empirical data was then processed using the Structural Equation Model Partial Least Square (SEM PLS) to test some of the hypotheses proposed. The results of the study explained that Behavioral Intention proved to have a positive effect on Use Behavior, but Facilitating Conditions proved to have no effect on Use Behavior. Effort Expectations and Social Influence have been shown to have a positive effect on Behavioral Intentions, whereas Attitudes, Performance Expectations, and Facilitation Conditions have been shown to have no effect on Behavioral Intentions. In addition, Trust and Effort Expectations have been shown to have a positive effect on Attitudes, but Performance Expectations have been shown to have no effect on Attitudes. The implications of this research become a reference for the banking industry in designing a payment system in the form of the QRIS feature as a means of digital payment transactions.

Keywords: QRIS; Trust; Attitude; Behavioral Intention; Use Behaviour.
PENGARUH CITRA MEREK, KUALITAS PRODUK, DAN PROMOSI TERHADAP LOYALITAS KONSUMEN DENGAN KEPUASAN KONSUMEN SEBAGAI VARIABEL INTERVENING PADA PRODUK INDOMIE DI SUPERINDO KECAMATAN BABELAN, KABUPATEN BEKASI
Authors: FoEh John EHJ , Anggoro Dimas Priyo
Published: January 2023

Abstract- The purpose of this study was to determine the effect of the independent variables, namely brand image, product quality and promotion on the dependent variable, namely consumer loyalty through the intervening variable, namely customer satisfaction. This research was conducted in Superindo, Babelan District, Bekasi Regency. The method used in this study is a quantitative method. The data used in this study is primary data using a questionnaire. The sampling method in this study used the Accidental Sampling technique. The population of this research is all consumers who visit Superindo, Babelan District, Bekasi Indomie Regency, which an average of 580 visitors in a month. The number of samples used in this study was 221 respondents calculated using the table for determining the number of samples developed by Isaac and Michael. The method of analysis uses Descriptive Quantitative Analysis, Multiple Linear Regression Analysis and Path Analysis. The data was processed using SPSS version 25 data analysis software. The results of this study indicate that brand image, product quality and promotion simultaneously or partially have a positive and significant effect on consumer satisfaction, while brand image, product quality and customer satisfaction partially have a positive and significant effect on consumer loyalty of Indomie products in Superindo, Babelan District, Bekasi Regency

Keywords: Consumer Loyalty; Brand Image; Product Quality; Promotion; Consumer Satisfaction
EMOTIONLESS DECISION. A COIN FLIP INVESTMENT DECISION, IS THAT WORTHED?
Authors: Kiky Andreas
Published: January 2023

Abstract- This article tries to test whether emotionless decisions (a coin flip) in investment decision-making could outperform human judgment due to superiority in avoiding behaviour bias caused by emotion. However, research about a coin flip in the investment decision is rarely can be found due to a lack of a solid foundation. Research problem in this article: Would the coin flip in investment decisions outperform human judgment in terms of investment wealth under the short-term trading range? The originality of this research is no prior research has been interested in checking the superiority of coin flip decisions in real investment due to the risk of uncertainty. This research finds a suitable environment (stock market competition) as the place to check the validity of the idea. This research uses a simple coin flip experiment to decide whether to sell or hold the investment asset during the stock competition. The result of investment wealth from the coin flip will be compared with the rest of the participants. A standard normal distribution (z) and (t) is used to check whether the coin flip wealth consistently falls into the top 5% or 1% of the right tail. Before that, the Kolmogorov-Smirnoff test is conducted to ensure the distribution follows the normal distribution shape. Using a coin flip for investment decisions is not outperform human judgment and winning the competition. Investment decision-making is an art between handling complex rational thinking about risk and managing the emotion in the process.

Keywords: Coin Flip Decision; Investment Decision; Stock Competition; Emotionless Decision
LEVERAGE EFFECT BETWEEN ISLAMIC STOCK AND SRI INDICES: CASE OF INDONESIA
Authors: Hendranastiti Nur Dhani
Published: January 2023

Abstract- This paper examines the difference in leverage effect between the Islamic stock index and the SRI index using the Indonesian data for a period before and during-after the COVID-19 pandemic. The interrelated issues of health and environment, starting from the COVID-19 pandemic, energy use, and environmental issues can have a different effects on different asset classes. With the distinctive feature of the Islamic stock index and SRI index, it can attract investors who want to diversify their portfolio to hedge against the health and environmental crisis. This study aims to examine the volatility risk in ISSI and SRI-Kehati as an impact of various events in 2020-2022. This paper attempts to test the leverage effect for a longer period incorporating the various major events in 2020-2022. This study uses daily price index data of ISSI and SRI-Kehati Index for the period  10/04/2013-28/11/2022 and employed the ARMA-EGARCH models to answer the objectives. The results show that there is a leverage effect in ISSI and SRI-Kehati for a period before and during-after the COVID-19 pandemic although the magnitude is lower after the during-after pandemic. The leverage effect indicates that the negative return that occurred in the constituents of both indices leads to higher volatility, implying that both indices are not prone to various events. The lower magnitude of the leverage effect on SRI-Kehati can give better assurance for investors regarding the volatility risk of the index.

Keywords: Islamic Stock Index; SRI Index; COVID-19; Crisis; Leverage Effect
Penggunaan Metode Bermain Peran Terhadap Hasil Belajar
Authors: Nadzirun Nadzirun , Saputra Andika Ari , Arifin M. Zainal , Mushodiq Muhamad Agus , Ningsih Diah Retno , Muslimah Muslimah , Permana Hara
Published: January 2023

Tujuan dalam penelitian ini yaitu untuk mengetahui  penggunaan metode bermain peran, untuk mengetahui hasil  belajar dan untuk mengetahui pengaruh penggunaan metode bermain peran terhadap hasil belajar. Metode yang penulis gunakan dalam penelitian ini yaitu metode bersifat deskriptif kuantitatif (deskriptif research),diantaranya menggunakan kuesioner, observasi, dokumentasi, dan Interview. Penelitian ini sampelnya berjumlah 24 siswa. Kemudian untuk membuktikan kebenaran hipotesis, penulis menganalisa data dengan rumus chi kuadrat. Berdasarkan hasil analisa data dengan menggunakan rumus chi kuadrat tersebut dapat diketahui bahwa harga chi kuadrat hitung (x2 hit) sebesar 6,12. Harga chi kuadrat hitung (x2 hit) adalah lebih besar dari harga chi kuadrat tabel (x2 tab) pada taraf signifikan 5% dan lebih kecil pada taraf signifikan 1% atau 5,991<6,12<9,210. Dengan demikian dapat disimpulkan bahwa ada pengaruh penggunaan metode bermain peran terhadap hasil belajar.
Actualization of State Defense Attitudes in the Context of Awareness of the Covid-19 Health Protocol
Authors: Ardani Ardani , Fitrayadi Dinar Sugiana , Bahrudin Febrian Alwan
Published: January 2023

Pandemik Covid-19 tidak hanya berdampak pada kesehatan saja, namun sektor-sektor lainnya juga terdampak dengan mewabahnya Covid-19. Pandemik Covid-19 akan menjadi masalah kompleks bagi negara jika terjadi berkepanjangan dan tidak ditangani secara benar. Penelitian ini bertujuan untuk mengetahui bagaimana aktualisasi dari sikap bela negara dalam konteks kesadaran menerapkan protokol kesehatan covid-19 pada masyarakat di lingkungan Pasar Rau Kota Serang, Provinsi Banten. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan metode deskriptif, data dikumpulkan melalui teknik observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukan bahwa pemahaman dan kesadaran tentang penerapan aturan protokol kesehatan covid-19 sebagai bentuk bela negara yang dilakukan oleh masyarakat masih rendah, disebabkan rendahnya literasi tantang pencegahan Covid-19 ditambah adanya pandangan yang salah tentang covid-19. Diperlukannya upaya dari pemerintah Kota Serang dan juga masayarakat dalam mengatasi bahaya covid-19, sementara masih terdapatnya hambatan yang dihadapi masyarakat dalam penerapan aturan protokol kesehatan. Disaat kondisi pandemik covid-19 ini masyarakat dapat mengaktulisasikan upaya bela negara dengan memiliki pemahaman dan kesadaran untuk melakukan pencegahan dari covid-19, sebab bela negara mencakup hal yang luas dalam kehidupan berbangsa dan bernegara. Pemerintah dan masyarakat harus bekerjasama dalam mengatasi dan menghadapi pandemik covid-19. Pemahaman dan kesadaran masyarakat yang baik dalam mencegah covid-19 dapat meminimalkan terjadinya infeksi penularan covid-19 dan mengurangi dampak yang ditimbukan dari covid-19.Kata kunci: Bela negara, Covid-19, Protokol Kesehatan
Shaping of Moral People Towards Law Compliance from A Western Theory Perspective
Authors: Lokman Hairul Faiezi Bin , Karim Amyza Nyirong , Din Nur Adlin Nabilah , Theevaheran Danisha
Published: January 2023

A moral person is a personal characteristic in terms of good and bad behavior that is prominent and accepted in a community context. Law compliance is a necessity in an individual's life that is surrounded by various codes of conduct and ethics to create a perfect life. Shaping moral people from various perspectives is a basis and guide to life. This article discusses the view of the western theoretical perspective in shaping law compliance. As a bibliographic study, this paper presents qualitative findings based on detailed references from journals, articles, books and newspapers. The findings are then elaborated thematically with narrative writing. Based on the findings of the study, shaping moral people towards law compliance can be practiced through the perspective of three western theories, namely utilitarianism, personality virtue and deontology theories. Research findings are also discussed based on examples and descriptions.
Strategies to Strengthen the Affective Domain in Learning Pancasila and Citizenship Education for Class XII Students of MAN 4 Pandeglang
Authors: Fujiana Uus , Damanhuri Damanhuri , Legiani Wika Hardika
Published: January 2023

This study aims to determine the strategies to strengthen the affective domain in Civics learning in class XII students and to determine the inhibiting and supporting factors in implementing the affective domain strengthening strategy in Civics learning in class XII students at MAN 4 Pandeglang. This research uses a type of qualitative approach with descriptive methods. The results found were that the strategy of strengthening the affective domain of students used learning models and methods aimed at improving the affective domain of students for the better, such as the habituation model in the form of assignment methods and monitoring good attitudes and behavior of students, exemplary models in the form of method of displaying good attitude and behavior. The strategy to strengthen the affective domain can run well and students can follow and be able to achieve the goals of strengthening the affective domain. Then the way to overcome the obstacles experienced in implementing the strategy to strengthen the affective domain in Civics learning is to use a personal approach to students, especially students whose affective domain or attitude is lacking and also students who experience difficulties in learning.
METHODOLOGY OF LITERARY SEARCH ON THE EXAMPLE OF PATIENTS WITH TUMORS OF THE PAROTID SALIVARY GLANDS WITH FACIAL NERVE DAMAGE AFTER RADICAL SURGERY
Authors:   Kazan (Volga Region) Federal University, Zinchenko S. V. , Muratov N. F. ,   Kazan (Volga Region) Federal University, Shanazarov N. A. ,   The Medical Centre Hospital of the President’s Affairs Administration of the Republic of Kazakhstan, Shanazarov N. A. ,   The Medical Centre Hospital of the President’s Affairs Administration of the Republic of Kazakhstan, Avdeev A. V. ,   The Medical Centre Hospital of the President’s Affairs Administration of the Republic of Kazakhstan
Published: January 2023

The issue of a systematic full-fledged literary search in the study of narrow issues of oncology is of no small interest today. The collection of complete up-to-date information on the issue raised, in this case, the issue of radical treatment of primary tumors of the large parotid salivary glands, is very relevant, objectively reflecting the researcher’s ability to analyze the data obtained [1]. The purpose of this study was the need to systematize the methodology of literary search by the example of studying the issue of complications after radical surgery for neoplasms of the parotid salivary glands. The article examines the opinions of experts with the largest number of citations on this issue. Material and methods. The literature was searched in the databases Scopus, Web of Science. In particular, we consider the existing volume of literature related to facial nerve injuries after radical interventions, identifying the most active scientists, journals and relevant publications. Conclusions. The article analyzes the existing volume of literature in this field. The total number of articles in the «general» category is 2254 documents, and analyzing the chronological development of publications, we can conclude that this topic became widespread only in the 1980s. The number of publications devoted to this topic today is 51. Significant progress has been observed only after the 2010-s.
HISTORY OF LOCAL ANESTHESIA
Authors:   Kazan (Volga Region) Federal University, Zinchenko S. V. , Fatkhutdinov I. M. ,   Kazan (Volga Region) Federal University, Akhmadeeva D. А. ,   Kazan State Medical University
Published: January 2023

The analgesic properties of coca leaves have been known to the Mayan tribes since the 2nd millennium BC. Local anesthesia begins its official history since the middle of the 19th century. In 1859, the German chemist Albert Neumann (1834 – 1861), who worked at the University of Göttingen, isolated a 0,25% alkaloid in its pure form, which he called «cocaine». The scientist noticed the numbness of the tongue that occurs after contact with cocaine. The art of local anesthesia is very dynamic, this is reflected both in the development of this direction at the present time and in its history. To date, the history of local anesthesia has more than 160 years. Over the specified period of time, local anesthesia has undergone major changes. Local anesthetics are a legacy that preserves the many years of work of scientists and doctors, their experience. With their help, millions of patients in the world every day get rid of pain during operations and various surgical interventions. This study uses general methodological approaches for historical and medical research, reflecting the dynamics of the development of local anesthesia in medicine, its role at the present stage of the development of medical science. Based on the data obtained, the following stages of the development of local anesthesia can be distinguished. It all started with terminal anesthesia, then there was a stage of infiltration anesthesia, which is still widely used today. At the beginning of the 20th century, doctors began to practice case anesthesia. This technique has expanded the possibilities of local anesthesia. The use of local anesthetics for regional anesthesia is the highest level of its application. Local anesthesia is currently at the next stage of its development. Today we have a wide variety of local anesthetics, and local anesthesia is increasingly being used in pediatric surgery. Understanding history allows us to expand the horizons of our knowledge.
Identification of new dihydrophenanthrene derivatives as promising anti-SARS-CoV-2 drugs through in silico investigations
Authors: Yamari Imane , Abchir Oussama , Nour Hassan , El Kouali Mhammed , Chtita Samir
Published: January 2023

To research, evaluate, and invent novel compounds that inhibit SARS-CoV-2 activity, a series of reported 39 substituted 9, 10-dihydrophenanthrene derivatives were subjected to a quantitative structure-activity relationship (QSAR) study. Gaussian 09 and ChemOffice programs were used to calculate the molecular descriptors employed to determine their impact on the studied activity. Then we reduced the number of descriptors by eliminating the redundant information using principal component analysis (PCA). The creation of molecular models was done by using multiple linear regression (MLR) according to the principles established by the Organization for Economic Co-operation and Development (OECD) and the validation by using external and internal validation, Y-randomization tests, and domain of applicability. Moreover, we evaluated the toxicity of developed compounds using ADMET and Molecular docking to determine their optimal position to form a stable complex. As a result, four molecules may be used to develop a novel drug that can inhibit SARS-CoV-2 without causing the side effect.
Cortical hemodynamic response during cognitive Stroop test in acute stroke patients assessed by fNIRS
Authors: Heiberg Adam Vittrup , Simonsen Sofie Amalie , Schytz Henrik Winther , Iversen Helle Klingenberg
Published: January 2023

BACKGROUND: Following acute ischemic stroke (AIS) many patients experience cognitive impairment which interferes neurorehabilitation. Understanding and monitoring pathophysiologic processes behind cognitive symptoms requires accessible methods during testing and training. Functional near-infrared spectroscopy (fNIRS) can assess activational hemodynamic responses in the prefrontal cortex (PFC) and feasibly be used as a biomarker to support stroke rehabilitation. OBJECTIVE: Exploring the feasibility of fNIRS as a biomarker during the Stroop Color and Word Test (SCWT) assessing executive function in AIS patients. METHODS: Observational study of 21 patients with mild to moderate AIS and 22 healthy age- and sex-matched controls (HC) examined with fNIRS of PFC during the SCWT. Hemodynamic responses were analyzed with general linear modeling. RESULTS: The SCWT was performed worse by AIS patients than HC. Neither patients nor HC showed PFC activation, but an inverse activational pattern primarily in superolateral and superomedial PFC significantly lower in AIS. Hemodynamic responses were incoherent to test difficulty and performance. No other group differences or lateralization were found. CONCLUSIONS: AIS patients had impaired executive function assessed by the SCWT, while both groups showed an inverse hemodynamic response significantly larger in HC. Investigations assessing the physiology behind inverse hemodynamic responses are warranted before deeming clinical implementation reasonable.
Pulsed electromagnetic field attenuates bone fragility in estrogen-deficient osteoporosis in rats
Authors: Popović Tamara , Matavulj Milica , Nežić Lana , Radulović Tatjana Nožica , Škrbić Ranko
Published: January 2023

BACKGROUND: The pulsed electromagnetic fields (PEMFs) seem effective in increasing bone mineral density and promoting osteogenesis and bone healing. OBJECTIVE: To examine the effect of two different modalities of PEMFs therapy in comparison with the recommended pharmacological treatment on experimental osteoporosis in rats. METHODS: The experimental model of estrogen-deficient osteoporosis induced by ovariectomy was used in this study. The animals were exposed to PEMFs of various frequencies (40 Hz and 25 Hzk), intensities (10 mT and 36.4 μT), lengths of exposure, and the effects were compared with the standard treatment with pamidronate, vitamin D, and calcium supplementation. RESULTS: The application of PEMF40Hz, significantly reduced the osteoporotic bone loss in female rats that were confirmed with biochemical, biomechanical, and histological analyses. These effects were more pronounced than in osteoporotic animals treated with pamidronate, vitamin D, and calcium supplementation. On the contrary, the exposure to PEMF25Hz did not show restorative effects but led to further progression of osteoporosis. CONCLUSION: The exposure to PEMF40Hz, significantly restored osteoporosis and attenuated bone fragility in comparison to the rats exposed to PEMF25Hz or those treated with pamidronate, vitamin D, and calcium supplementation.
HPC+ in the medical field: Overview and current examples
Authors: Koch Miriam , Arlandini Claudio , Antonopoulos Gregory , Baretta Alessia , Beaujean Pierre , Bex Geert Jan , Biancolini Marco Evangelos , Celi Simona , Costa Emiliano , Drescher Lukas , Eleftheriadis Vasileios , Fadel Nur A. , Fink Andreas , Galbiati Federica , Hatzakis Ilias , Hompis Georgios , Lewandowski Natalie , Memmolo Antonio , Mensch Carl , Obrist Dominik , Paneta Valentina , Papadimitroulas Panagiotis , Petropoulos Konstantinos , Porziani Stefano , Savvidis Georgios , Sethia Khyati , Strakos Petr , Svobodova Petra , Vignali Emanuele
Published: January 2023

BACKGROUND: To say data is revolutionising the medical sector would be a vast understatement. The amount of medical data available today is unprecedented and has the potential to enable to date unseen forms of healthcare. To process this huge amount of data, an equally huge amount of computing power is required, which cannot be provided by regular desktop computers. These areas can be (and already are) supported by High-Performance-Computing (HPC), High-Performance Data Analytics (HPDA), and AI (together “HPC+”). OBJECTIVE: This overview article aims to show state-of-the-art examples of studies supported by the National Competence Centres (NCCs) in HPC+ within the EuroCC project, employing HPC, HPDA and AI for medical applications. METHOD: The included studies on different applications of HPC in the medical sector were sourced from the National Competence Centres in HPC and compiled into an overview article. Methods include the application of HPC+ for medical image processing, high-performance medical and pharmaceutical data analytics, an application for pediatric dosimetry, and a cloud-based HPC platform to support systemic pulmonary shunting procedures. RESULTS: This article showcases state-of-the-art applications and large-scale data analytics in the medical sector employing HPC+ within surgery, medical image processing in diagnostics, nutritional support of patients in hospitals, treating congenital heart diseases in children, and within basic research. CONCLUSION: HPC+ support scientific fields from research to industrial applications in the medical area, enabling researchers to run faster and more complex calculations, simulations and data analyses for the direct benefit of patients, doctors, clinicians and as an accelerator for medical research.
Verification of temperature, wind and precipitation fields for the high-resolution WRF NMM model over the complex terrain of Montenegro
Authors: Zečević Aleksandar , Filipović Luka , Marčev Angel
Published: January 2023

BACKGROUND: The necessity of setting up high-resolution models is essential to timely forecast dangerous meteorological phenomena. OBJECTIVE: This study presents a verification of the numerical Weather Research and Forecasting non-hydrostatic Mesoscale Model (WRF NMM) for weather prediction using the High-Performance Computing (HPC) cluster over the complex relief of Montenegro. METHODS: Verification was performed comparing WRF NMM predicted values and measured values for temperature, wind and precipitation for six Montenegrin weather stations in a five-year period using statistical parameters. The difficult task of adjusting the model over the complex Montenegrin terrain is caused by a rapid altitude change in in the coastal area, numerous karst fields, basins, river valleys and canyons, large areas of artificial lakes on a relatively small terrain. RESULTS: Based on the obtained verification results, the results of the model vary during time of day, the season of the year, the altitude of the station for which the model results were verified, as well as the surrounding relief for them. The results show the best performance in the central region and show deviations for some metrological measures in some periods of the year. CONCLUSION: This study can give recommendations on how to adapt a numerical model to a real situation in order to produce better weather forecast for the public.
Changes in Lung Function and Exercise Capacity after Aerobic Training and Muscle Strength Training to Patient with Post-COVID Condition(Case Study)
Authors:   Korean Academy of Cardiorespiratory Physical Therapy, Lee Seung-Yub , Choi Won-Jye
Published: January 2023

Purpose: This study was designed to investigate the changes in lung function and exercise capacity after the application of aerobic training and strength training to a patient with post-COVID condition.
Methods: Aerobic training and weight training were performed for 4 weeks. The results of the lung function test and 6-min walking test before and after training were compared.
Results: The results of this study showed that forced vital capacity increased from 4.21 L (predicted 79.2%) to 4.98 L (predicted 94.1%), and the 6-min walking distance increased from 542 m (predicted 76.7%) to 718 m (predicted 101.2%).
Conclusion: Lung function and exercise capacity were increased after the application of aerobic training and strength training.
MAIN FACTORS OF THE NEGATIVE IMPACT OF THE COVID-19 PANDEMIC ON MENTAL HEALTH OF CHILDREN
Authors: Hozak S.V. , Yelizarova O.T. , Stankevych T.V. , Parats A.N.
Published: January 2023

Relevance. It is widely recognized that COVID-19 disease is significant problem for public health. The COVID-19 pandemic evolves, the long-term health impacts are continually increasing and children health is particular concern.  The duration of exposure, heterogeneity and plurality of biopsychosocial factors  have to unpredictable consequences on the mental health of vulnerable populations such as children and adolescents.

Objective. Determination the significant factors affecting the mental health of schoolchildren during the pandemic in order to further develop the health-saving measures.

Methods. During implementation of quarantine measures due to COVID-19 pandemic, we studied the peculiarities of schoolchildren’s life and mental health in 2020-2021 (n=1393) from all regions of Ukraine. Q-RAPH, GPAQ, RCADS-P-25 questionnaires were used. Prior to the pandemic, MH survey of 500 schoolchildren was conducted using “Children’s Neuroses Questionnaire” method. Descriptive statistics, Student's coefficients, univariate and multivariate analysis of variance, followed by a posteriori estimation of mean differences according to the Bonferroni test, conjugation tables, logistic and linear regression models were used.

Results. Сonstant stay in an apartment during quarantine leads to an increase in the chances of anxiety-depressive disorders on average by 2.5 times. During the pandemic for the observation period, both duration and frequency of walks were significantly lower for the children with mental disorders. The likelihood of pathological increases in anxiety and depression in school age children without interactive learning is 1.8 times greater. Pairwise comparisons of adjusted means using the Bonferroni test demonstrated that the higher is the BMI - the shorter is the sleep (β=-1.9; p=0.004), the longer is the sedentary behavior duration (β=3.4; p=0.001) - the shorter is MVPA (β =-1,4; p=0,005). It was established that depressive disorders are 2.4 times more common among the children with chronic diseases than among the healthy children (χ2 =51.1; p<0.001). In the course of 3d linear modeling of normalized indicators we can see that a decrease in both light physical activity (LPA) and MVPA leads to deterioration in mental health indicators of the children.

Conclusions. Main factors of the negative impact on children's mental health during the COVID-19 pandemic are: permanent stay at home (OR=2.02; CI 1.39-2.93), frequency of walks less than 4 times a week and duration less than 220 minutes per week (OR=1.96; CI 1.12-3.45), non-interactive remote learning (OR=1.78; CI 1.17-2.69), overweight and obesity of schoolchildren (OR=1 .52; CI 1.11-2.08), presence of chronic diseases (OR=2.79; CI 1.99-3.91), anxiety disorders in parents (OR=3.67; CI 1.02-13,25) and their lack of higher education (OR=1,27; CI 1,03-1,56).

The obtained results must be taken into account when developing further preventive strategies and tactics for overcoming the pandemic consequences.
Ultrasound features of prenatally diagnosed ovarian cysts: what is important for the prognosis
Authors:   Belarusian Medical Academy of Postgraduate Education, Minsk, Republic of Belarus, Tihonenko I.V.
Published: January 2023

Aim: to assess the outcomes of prenatally diagnosed ovarian cysts and to identify ultrasound features associated with the prognosis of surgical treatment Patients and Methods: this retrospective study evaluated 59 fetal ovarian cysts diagnosed during ultrasound screening in the prenatal ultrasound center. The following parameters were reviewed: parity, maternal age, time of prenatal diagnosis, ultrasound cystic features and structure, and the outcomes of fetal ovarian cysts. Results: fetal ovarian cysts were detected during pregnancy in women with a median age of 30.6 years (17–42 years), 40.7% of them were primipara. A median gestational age at the date of prenatal cyst diagnosis was 33.5 (21.2–38) weeks of pregnancy. In 25.4% of cases the ovarian cysts had complex echotexture, and in 33.2% of cases a cyst diameter was ≥40 mm. In 32.2% of cases, the cysts were located at some distance from the bladder; 39% of the cysts were fully or partially visualized in the abdomen. The spontaneous cyst resolution by the time of delivery was reported in 37.3% of cases, including 40% of complex cysts. After birth, 35.6% of ovarian cysts disappeared and 20% of complex cysts demonstrated regression. Also, the regression occurred in 26.3% of cysts ≥ 40 mm. Overall, spontaneous resolution was reported for 60% of complex cysts, 42.1% of cysts ≥40 mm, 52.6% of cysts distinct from the bladder and 56.5% of cysts located in the abdomen. Postnatal surgery was performed in 27.1% of the newborn girls. The likelihood of surgical treatment was higher in the newborns with prenatal cysts ≥ 40 mm comparing to cysts < 40 mm (odds ratio (OR), 7.78 (95% confidence interval (CI), 2.12–28.53)) and cysts located in the abdomen comparing to cysts located in the fetal pelvis (OR, 16.25 (95% CI, 3.84–68.82)). No correlation was found between ultrasound features of ovarian cysts and torsion Conclusion: the ultrasound features of prenatally diagnosed ovarian cysts which are important for predicting a higher risk of postnatal surgical procedures include the cyst diameter (≥ 40 mm) and the location (especially in the abdomen). These factors should be taken into consideration for choosing a maternity hospital and prenatal consulting of parents. KEYWORDS: fetal ovarian cyst, prenatal diagnosis, ultrasound features, outcome, prognosis. FOR CITATION: Tihonenko I.V. Ultrasound features of prenatally diagnosed ovarian cysts: what is important for the prognosis. Russian Journal of Woman and Child Health. 2022;5(4):287–291 (in Russ.). DOI: 10.32364/2618-8430-2022-5-4-287-291.
Ecofucin® for the prevention of vaginal microbiota dysbiosis — bacterial vaginosis and candidiasis amid the use of systemic antimicrobial therapy
Authors:   A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation, Kuzmin V.N.
Published: January 2023

Aim: to assess the efficacy and safety of Ecofucin® in patients after performing planned gynecologic surgery procedures based on the changes in vaginal microbiota over time amid the use of systemic antimicrobial therapy (AMT). Patients and Methods: this prospective open randomized comparative parallel-group clinical study involved patients without signs of vaginal microbiota dysbiosis — bacterial vaginosis or candidiasis, who were hospitalized for planned surgery procedures. The group 1 patients (n=39) received systemic AMT and Ecofucin® for intravaginal application once a day at the bedtime for 12 days, starting 6 days before the planned surgery and AMT initiation, while the group 2 patients (n=40) received only systemic AMT. The efficacy was assessed a day after the completion of AMT and the use of the tested medication (i.e. on day 13 after the initiation of Ecofucin application) and 30±2 days after the initiation of using the tested drug. Clinical, microbiological and molecular genetic methods were used for the assessment. Results: symptoms common for vaginal microbiota dysbiosis — bacterial vaginosis and candidiasis were reported by 18% and 21% of the group 2 patients at days 13 and 30±2 after the initiation of AMT, while such symptoms were not recorded in any of the group 1 patients (F=0,107, р=0,007). In 100% of the group 1 patients both lactobacilli and bifidobacteria were detected at all endpoints. In group 2, lactobacilli were found at days 13 and 30±2 in 93.8% and 97% of patients, respectively (F=0.035, p=0.2; F=0.017, p=0.458), bifidobacteria — in 84.4% and 81.1% of patients, respectively (F=0.092, р=0.016; F=0.107, р=0,007, respectively). At the baseline, the groups had similar results of the vaginal discharge culture tests. In the group 1 patients, Candida spp. were not identified at any of the endpoints, in group 2 — Candida spp. were found in 22.5% of patients, starting from day 13 (F=0,125, р=0,002). No adverse events were reported. Conclusion: the administration of Ecofucin® vaginal suppositories containing natamycin 100 mg and excipient lactulose is effective for preventing microbiota dysbiosis — bacterial vaginosis and candidiasis in patients receiving antimicrobial therapy. KEYWORDS: vagina, microbiocenosis, antimicrobial therapy, lactobacilli, bifidobacteria, candidiasis, natamycin, lactulose. FOR CITATION: Kuzmin V.N. Ecofucin® for the prevention of vaginal microbiota dysbiosis — bacterial vaginosis and candidiasis amid the use of systemic antimicrobial therapy. Russian Journal of Woman and Child Health. 2022;5(4):292–296 (in Russ.). DOI: 10.32364/2618-8430- 2022-5-4-292-296.
2018–2019 Florida Citrus Production Guide: Root Health Management
Authors: Johnson Evan G. , Graham James H. , Morgan Kelly T.
Published: January 2023

This 3-page fact sheet is part of the 2018–2019 Florida Citrus Production Guide. Written by E. G. Johnson, J. H. Graham, and K. T. Morgan, and published by the Agronomy Department, January 2019.
CMG15/CG094: 2022–2023 Florida Citrus Production Guide: Root Health Management (ufl.edu)
‘Lava Glow’—A New Red Fancy-Leaved Caladium Cultivar
Authors: Deng Zhanao , Peres Natalia A. , Desaeger Johan
Published: January 2023

‘Lava Glow’ is a new and novel caladium cultivar that produces bright red to red-purple heart-shaped leaves with strong sunburn tolerance and is resistant to leaf spot diseases. This new 7-page publication of the UF/IFAS Environmental Horticulture Department is prepared for growers who are interested in growing caladium as a horticultural crop and for greenhouse or nursery growers who are interested in producing potted caladium plants. Written by Zhanao Deng, Natalia A. Peres, and Johan Desaeger.https://edis.ifas.ufl.edu/ep633
Vida Saludable: Diabetes
Authors: Bobroff Linda B.
Published: January 2023

La diabetes es una condición en la que el cuerpo tiene dificultad de producir o utilizar la insulina. La insulina es una hormona que controla la cantidad de glucosa (azúcar) en nuestra sangre. Cuando una persona tiene diabetes, el cuerpo no produce insulina o produce muy poca insulina o una insulina que no funciona bien. Esto resulta en altos niveles de glucosa en la sangre.
This 4-page fact sheet is a major revision that discusses diabetes, possible consequences of high blood glucose, risk factors, healthy weights, symptoms, control methods, and ways to choose a healthy diet. Written by Linda B. Bobroff, and published by the UF Department of Family, Youth and Community Sciences, October 2016.
Prevencion de Caidas: Estilos de vida y riesgo de caidas
Authors: Bobroff Linda B.
Published: January 2023

Hay muchos factores que pueden contribuir a las razones por las que usted se cae, pero algunos de éstos, los puede cambiar. A continuación le ofrecemos algunos cambios sencillos que puede hacer para reducir el riesgo de caerse.
This 2-page fact sheet is a major revision of the Spanish-language version of FCS2230/FY736: Fall Prevention: Lifestyle Factors and Fall Risk. Written by Linda B. Bobroff, and published by the UF Department of Family, Youth and Community Sciences, April 2016.
Managing Scale Insects on Ornamental Plants
Authors: Buss Eileen A. , Dale Adam
Published: January 2023

Scale insects are a diverse group of piercing-sucking pests (Hemiptera) commonly found on ornamental plants in landscapes and nurseries. There are over 180 species of scale insects in Florida, but only a small percentage are important pests of ornamental plants. They damage plants and secrete a waxy covering that makes them difficult to control using most chemical control measures. This revised 6-page fact sheet differentiates between armored and soft-scale insect pests and lists common types of each, provides information about the biology of scale insects and how to identify them and the damage they cause, describes how to scout and monitor for scale insects, and lists several methods for prevention and control of scale insect invasions. Written by Eileen A. Buss and Adam Dale, and published by the Department of Entomology and Nematology, July 2016.
ENY-323/MG005: Managing Scale Insects on Ornamental Plants (ufl.edu)
Pecan Truffle (Tuber lyonii): A Gourmet Truffle Native to the Southeastern United States
Authors: Grupe Arthur C. , Brenneman Timothy , Bonito Gregory , Smith Matthew E.
Published: January 2023

A truffle is a round, knobby, or lobed mushroom fruiting body that forms below ground. The “pecan truffle” (Tuber lyonii) is an edible truffle species, native to eastern North America. This fungus lives in a mutually beneficial relationship with the roots of some trees, including species of oak, hazelnut, and hickory trees, as well as the cultivated pecan tree. This 4-page fact sheet describes the pecan truffle, its economic and culinary significance, morphology, and phenology and distribution. Written by Arthur C. Grupe II, Timothy Brenneman, Gregory Bonito, and Matthew E. Smith, and published by the Plant Pathology Department, October 2016.
PP330/PP330: The Pecan Truffle (Tuber lyonii): A Gourmet Truffle Native to the Southeastern US (ufl.edu)