bluuebunny/crossref_metadata_2025 huggingface dataset:
The Observatory Health Report
Authors: Murianni Laura , Longhi Silvia , Ricciardi Walter
Published: June 2024

Background: The number of indicators aiming to provide a clear picture of healthcare needs and the qualityand efficiency of healthcare systems and services has proliferated in recent years. The activity of the NationalObservatory on Health Status in the Italian Regions is multidisciplinary, involving around 280 public healthcare experts, clinicians, demographers, epidemiologists, mathematicians, statisticians and economists whowith their different competencies, and scientific interests aim to improve the collective health of individualsand their conditions through the use of “core indicators”. The main outcome of the National Observatory onHealth Status in the Italian Regions is the “Osservasalute Report – a report on health status and the qualityof healthcare assistance in the Italian Regions”.Methods: The Report adopts a comparative analysis, methodology and internationally validated indicators.Results: The results of Observatory Report show it is necessary:• to improve the monitoring of primary health care services (where the chronic disease could be cared)through implementation of clinical path;• to improve in certain areas of hospital care such as caesarean deliveries, as well as the average length ofstay in the pre-intervention phase, etc.;• to try to be more focused on the patients/citizens in our health care services;• to practice more geographical interventions to reduce the North-South divide as well as reduce gender inequity.Conclusions: The health status of Italian people is good with positive results and outcomes, but in themeantime some further efforts should be done especially in the South that still has to improve the quality andthe organization of health care services. There are huge differences in accuracy and therefore usefulness ofthe reported data, both between diseases and between Regions.
Rapid pulsed-field gel electrophoresis protocol for Legionella pneumophila typing
Authors: Orsini Massimiliano , Amore Rosarita , Pietrangeli Bianca Maria , Anastasi Daniela , Ricciardi Walter , Boccia Stefania
Published: June 2024

Background: Genomic DNA patterns generated by pulsed-field gel electrophoresis (PGFE) are highly specificfor different strains of an organism and have significant value in epidemiologic investigations of infectiousdisease outbreaks. A disadvantage of PFGE is that the procedure requires up to 6 days to complete.Methods: We developed a rapid PFGE protocol for subtyping Legionella pneumophila isolates based on thestandardized protocol currently used. Various combinations of reaction conditions (e.g., lysis time andtemperature, restriction enzyme concentration) and electrophoresis parameters were applied to devise asimple and rapid PFGE protocol that could also be used for frozen bacteria.Results: PFGE analysis of Legionella pneumophila isolates can be completed in 26 hours using this protocolcompared to 6 days for the conventional one.Conclusions: We successfully applied a rapid PFGE protocol for Legionella pneumophila typing andcomparison of the patterns obtained from the rapid compared with the conventional method showed that therapid protocol gave identical and highly reproducible results.
Development of a reliable and clinically useful Italian version of the Axis II of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD)
Authors: Macrì Ludovica Antonella , Deli Valeria , Deli Roberto
Published: June 2024

Background: Multiple-language versions of the same psychometric instrument are increasingly needed, butsimply translating an English version word-to-word into another language is not adequate to account forlinguistic and cultural differences. Our aim was to validate an Italian version of the Axis II of the ResearchDiagnostic Criteria for temporomandibular disorders (RDC/TMD) and to test its reproducibility in order to usethis important diagnostic instrument in Italian patients.Methods: The original English-language version was translated and culturally adapted for Italian-speakingpeople, back-translated to English and then tested on 68 subjects: 34 TMD patients and 34 healthy subjects.Internal consistency was assessed by calculating the Cronbach coefficient alpha for the entire scale in the twosamples. The reproducibility of the domains was assessed with the use of the Spearman-Brown test-retestreliability test, Wilcoxon matched pair test, Sign test and 2x2table Chi Square test according to the data types.Correlation of the initial and test-retest scores of the Axis II was measured with the Spearman rank correlationcoefficient as an additional measure of reproducibility.Results: The Italian version of Axis II has a good reproducibility; the internal consistency (measured with theCronbach coefficient alpha) of the overall final questionnaire was excellent: 0.95.Conclusions: The Axis II Italian version appeared reliable and it could be useful to assess TMD patients andto standardize the data acquisition in this relevant and common disease.
Public health genomics in Europe
Authors: Boccia Stefania , Brand Angela , Brand Helmut , Schröder Peter , Khoury Muin J. , Zimmern Ron
Published: June 2024

The challenge of integrating genomics into public health The Human Genome Project was completed in 2003. Expectations are high that new knowledge and technologies arising from the project will soon contribute to the improvement of individual and population health. Yet, approaches in public health have so far not broadly used molecular knowledge of individual genetic susceptibility for achieving their goals. However, in the past decade there has been increasing awareness that advances in genomics can be utilised in public health in the near future. It is our opinion that it is of major importance to start discussion of this option and its possible consequences early enough. This thematic issue starts from the premise that public health approaches can and should no longer ignore the advances made in genomics.We are seeing the emergence of the multidisciplinary field of public health genomics that deals with these opportunities and challenges. According to the statements of an expert group that discussed public health genomics concepts in Bellagio in 2005, public health genomics can be defined as:“The responsible and effective translation of genome-based knowledge and technologies for the benefit of population health (Bellagio Report).”
The Agency for Healthcare Research and Quality
Authors: Baine William B.
Published: June 2024

The mission of the Agency for Healthcare Research and Quality is “to improve the quality, safety, efficiency,and effectiveness of health care for all Americans”. The organization and selected major activities of theAgency are briefly described.
Challenges for the Italian Public Health Genomics Task Force
Authors: Boccia Stefania , Ricciardi Walter
Published: June 2024

Dear Sirs,
In recent years, the results of the Human Genome Project have lead to huge expectations relating to the rapid implementation of its results in the field of prevention.The possibility to provide early detection for those individuals more susceptible to complex diseases, because of their genetic make-up, might theoretically result in individualized primary (e.g., chemoprevention) and secondary prevention (e.g., assiduous monitoring) programs.
The issue of an individuals inherited susceptibility to develop complex diseases, however, is much more complicated than it first appears, because of the delicate links between scientific developments, technical applications and ethical considerations. Consequently, besides the framework required for the critical evaluation of genetic testing (analytical validity, clinical validity and clinical utility of the test),we must also consider these three fundamental aspects:
 • From pooled and meta-analyses of genetic association studies, it appears that most of the commonly identified genetic variants (polymorphisms) confers a low risk of disease (on average ORs of 1.5, if not lower), which only increases with the interaction of well-known environmental risk factors
• From preliminary studies, the result from a ‘positive’ genetic testing does not seem to motivate behavioural changes;
• There is a need for an evidence-based approach to genetic testing that integrates the cost-utility evaluation of each available genetic test [Health Technology Assessment (HTA) framework] while considering the weight of the relevant ethical issues.
How I was converted from skeptic to enthusiast about meta- analysis
Authors: Maclure Malcolm
Published: June 2024

When I first heard of meta-analysis in the mid-1980s,I was suspicious.After slaving for 3 years on a case-control study of renal adenocarcinoma that yielded just 3 papers, the idea of someone else getting a quick publication by quantitatively pooling my findings with other studies seemed parasitic, if not plagiarist. On the other hand, I was aware that reviews of scientific literature often simply bolstered the authors’ opinions by citing supportive studies and glossing over, dismissing or overlooking unsupportive studies. My suspicion was reduced by Meir Stampfer’s important paper pooling results of streptokinase trials. I decided meta-analysis might be appropriate for drug trials. However, I was troubled by the conflict between the apparent goal of metaanalysis –- to achieve statistical significance or tight confidence intervals — and Rothman’s and others’ criticism of p-values. Meta-analysis seemed to me to be a fancy name for combining results to get a better p-value.
Quality assessment in meta-analysis
Authors: La Torre Giuseppe , Chiaradia Giacomina , Gianfagna Francesco , De Laurentis Angelo , Boccia Stefania
Published: June 2024

Background: An important characteristic of meta-analysis is that the results are determined both by themanagement of the meta-analysis process and by the features of studies included. The scientific rigor ofpotential primary studies varies considerably and the common objection to meta-analytic summaries is thatthey combine results from studies of different quality. Researchers began to develop quality scales forexperimental studies, however now the interest of researchers is also focusing on observational studies.Since 1980, when Chalmers developed the first quality scale to assess primary studies included in meta-analysis, more than 100 scales have been developed, which vary dramatically in the quality and quantity ofthe items included. No standard lists of items exist, and the used quality scales lack empirically-supportedcomponents.Methods: Two of the most important and diffuse quality scales for experimental studies, Jadad system andChalmers’ scale, and a quality scale used for observational studies, developed by Angelillo et al., aredescribed and compared.Conclusion: The fallibility of meta-analysis is not surprising, considering the various bias that may beintroduced by the processes of locating and selecting studies, including publication bias, language bias andcitation bias. Quality assessment of the studies offers an estimate of the likelihood that their results willexpress the truth
Socio-economic inequalities in injury incidence in the Netherlands
Authors: Van Beeck ED , Van Lenthe Frank , Toet Hidde , Den Hertog Paul , Van Baar Margriet
Published: June 2024

Background: Interventions to reduce socio-economic inequalities in injury incidence should be tailored tospecific priority areas that may be identified by descriptive studies. We aimed to provide an overview ofexisting socio-economic inequalities in injury incidence in the Netherlands and to assess the potentialinfluence of methodological choices on the relationships found.Methods: Self-reported medically treated injuries (all injuries versus fractures) were derived from a surveyamong a random sample of 59 063 persons. Injuries resulting in hospital admissions (all injuries versusfractures) were derived from a prospective cohort study of 18 810 participants, linked to the NationalHospital Discharge Register for a follow-up period of 7 years. Logistic regression was used to calculate theodds ratios of self-reported medically treated injuries and fractures by level of education, occupation andincome, and of hospital-admitted injuries by level of education and occupation.Results: Socio-economic inequalities in injury incidence in the Netherlands were dependent on the indicator ofnon-fatal injury incidence, indicator of socio-economic status (SES) and studied cause of injury. In the majorityof specific relations analyzed, injury risks were not or only moderately elevated in lower SES-classes. Analysesfocusing on injury with higher severity levels (admitted injuries and/or admitted fractures) revealed thesteepest SES gradient with odds ratios of injury of 1.5 or more of the lowest socio-economic (educational)groups compared to persons with higher SES (education). In hospital admitted traffic injuries, we found themost striking difference with a threefold higher risk in the lowest educational groups.Conclusion: Future descriptive research into socio-economic differences in injury incidence should includeall three core indicators of SES and separate analyses on the more severe injuries should be conducted.
Cesarean section rates in Italian regions: 1998-2002
Authors: Fantini Maria Pia , Dallolio Laura , Stivanello Elisa , Bravi Francesca , Savoia Elena
Published: June 2024

Cesarean section (c-section) rates have been increasing in many countries, and too frequently this rise doesnot seem to be justified by clinical grounds. To reduce c-section rates and achieve a proportion of 20% isamong the goals of the Italian National Health Plan. In the following paper we provide an update on thedistribution of rates amongst Italian regions and describe the association between regional hospitalvolumes and c-section rates. The national c-section rate increased from 31% in 1998 to 36% in 2002. Therates varied among regions and ranged from 20% in the Province of Bolzano to 56% in Campania. Asignificant association was observed between the regional hospital volumes for deliveries and c-sectionrates, regions with low hospital volumes performed more c-sections than high volume regions.
Perception of biological risk and food choices in university students in Naples
Authors: Cirillo Teresa , Agozzino Erminia , Amodio Cocchieri Renata , Del Prete Umberto
Published: June 2024

The aim of the present survey was to assess the perceived risk of foodborne infections in young adults witha high education level. The authors investigated their knowledge of foodborne infections, the preparationand storage of food that favour these infections and the rules of food safety and hygiene for consumerprotection, as well as their behaviour regarding personal hygiene and their eating habits outside the home.The results showed that they had a good level of knowledge across all of the fields investigated, but outsidethe home they tended to favour food products that have a high risk of foodborne infection.This confirms that lifestyle and eating habits are strongly influenced by socio-economic factors, fashion, themedia and by the market demands of the food industry.
N-Acetyltransferase 2 status and gastric cancer risk: a preliminary meta-analysis
Authors: Boccia Stefania , La Torre Giuseppe , Gianfagna Francesco , Ricciardi Gualtiero
Published: June 2024

In recent studies N- Acetyltransferase 2 (NAT2) genotype has been considered as a risk factor for developinggastric cancer, however with conflicting results among Asian and Caucasian populations. In order to clarifythe influence of NAT2 slow acetylation status on gastric cancer risk, a preliminary meta-analysis of publishedcase-control studies was undertaken. The primary outcome measure was the odds ratio (OR) for the risk ofgastric cancer associated with the NAT2 slow genotype using a random effects model. Pooling the resultsfrom the 5 studies identified (771 cases, 1083 controls), an overall OR for gastric cancer risk associated withthe NAT2 slow genotype of 0.91 emerged (95% CI: 0.54-1.55). The result suggests that the NAT2 slowgenotype has probably no effect on the risk of gastric cancer. Additional epidemiological studies, based onsample sizes that are commensurate with the detection of small genotypic risks, are required to confirmthese findings. Future studies may also help to clarify whether geographic differences exist.
Molecular biology as applied to the prevention of chronic-degenerative diseases. From preventive to predictive medicine
Authors: Izzotti Alberto
Published: June 2024

Dear Sir, Chronic-degenerative diseases (CDD), including atherosclerosis, cancer and chronic-obstructive pulmonary diseases, are the main causes of death in developed countries, accounting for approximately 90% of mortality. These pathologies arise from a complex network of risk-factors both exogenous and endogenous in origin.
The role of preventive medicine in counteracting this major public-health problem is pivotal, especially since treatment of these diseases is difficult. The goal of preventive medicine is to shed light on the network of CDDrelated risk factors in healthy subjects, thus allowing for primary preventive interventions aimed at removing harmful exposures, increasing host-defence mechanisms and activating targeted early-screening programs in susceptible individuals.CDD risk-factors are identified by anamnestic evaluation and questionnaires as well as chemical-laboratory analyses and the clinical examination of patients.
For example, the risk assessment for atherosclerosis is performed by analysing diet and smoke-exposure habits, measuring blood pressure, lipid profile, etc., however, a similar approach may only in part be pursued for cancer because the majority of the related pathogenic phenomena occurs at molecular level.
Glossary of terms for public health genomics
Authors: Rosenkötter Nicole , Kruppa Natalie , Budde Kirsten
Published: June 2024

In this Glossary the secretariat of PHGEN has compiled some of the terms relevant to Public Health Genomics. A more extensive version of this glossary can be found on the PHGEN-website www.phgen.eu.
Design-driven external analysis: A framework for adaptation and innovation in digitally native enterprises
Authors: Font-Cot Francesc , Lara-Navarra Pablo , Serradell-López Enric , Manetti Alessandro
Published: June 2024

Analysing external factors with a design-thinking approach is crucial for adaptation, identifying opportunities, and mitigating risks in native digital enterprises. This research introduces a framework rooted in design principles and future scenarios for external analysis, with the aim of meeting current market needs. The study employs a mixed qualitative-quantitative research approach, incorporating methods such as literature review, workshops, and surveys. These methods enable the collection and analysis of both qualitative and quantitative data, providing a comprehensive and accurate understanding of the research topic by using it in a DNVB case study. Developing a conceptual framework using a design-thinking approach which we call ASPECT contributes to a comprehensive interpretation of complexity, intertwining collective and individual factors. This reduces the risk of overlooking essential elements when making strategic decisions in ambiguous, uncertain, and volatile contexts. This method contrasts with traditional external analysis frameworks like CAME, Pestle, and SWOT. The document aims to contribute to the literature by exploring new models of external analysis based on the design process. This framework combines the conventional stages of a design thinking process with methodologies for future scenarios to identify relevant external factors for organizations. It provides an innovative conceptual framework for creating new business models and growth strategies for digital enterprises.
Unnotched impact toughness of polybutylene terephthalate/polyamide 6/carbon black blends
Authors: Ngo Quoc Bao , Hua Phan Hieu , Pham Thi Hong Nga , Vo Minh Trong Tin , Nguyen Thanh Tan , Pham Quan Anh , Hoang Van Huong , Tran The San , Ho Sy Hung , Nguyen Khac Nhan
Published: June 2024

The combination of polybutylene terephthalate (PBT) and polyamide 6 (PA6) plastic mixture was taken from waste from the table production process along with carbon black (CB) reinforcement with the desire to create a potential plastic mixture widely used in many fields. The PBT/PA6/CB mix is created by injection molding with a CB weight ratio of 0%, 4%, 8%, and 12%. This study has shown the change in plastic’s mechanical properties when adding CB to the mixture by testing the unnotched impact toughness according to ASTM D256 standards. Research results show that the unnotched impact toughness was gradually reduced when increasing the CB content in the mixture from 0% to 12% CB. Specifically, at 0% CB, the resulting unnotched impact toughness was 12.85 kJ/m2, reduced to 4.78 kJ/m2.
Test of Perception of Differences (CARAS-R): Analysis in A Sample of Peruvian Children and Adolescents
Authors: Castro Jonathan Ruiz , Blanco Arturo Zuñiga , Cabrera Eliana Magda Ibarra , Ccoa Verónica Luna
Published: June 2024

Objective: To examine differences in distributions of sustained attention (SA), impulsivity control index (ICI), errors of commission (Ec) and errors of omission (Eo) with respect to demographic variables (sex and school grade). To analyze differences at the secondary level in the regions of Peru. To relate age and school grade with AS and Eo.   Theoretical framework: The study is centered on the theoretical model of Posner and Petersen (1990); considering a neuropsychological approach to development and a visual search paradigm.   Method: It belongs to a quantitative approach, with a descriptive correlational scope and cross-sectional non-experimental design. The sampling was probabilistic by clusters, 6,564 students at the primary level and 4305 at the secondary level.   Results and Discussion: In AS, ICI, Ec and Eo there are statistical differences according to sex and school grade. On the other hand, there were associations between AS and Eo according to age and school grade. Finally, statistical differences were obtained in AS, ICI and Eo according to the three regions of Peru.   Implications of the research: The study provides new scientific evidence of attention in Peruvian children and adolescents.   Originality/value: The study is based on the typification of the instrument in the Hogrefe TEA editions publishing house (Spain). Likewise, the results presented are unpublished and contribute to provide new information for psychopedagogues, psychologists and educators.
Analisis Kandungan Formalin dan Boraks dalam Mi Kuning, Kerupuk Merah, dan Ayam Menggunakan Metode Rapid Test Kit dan Spektrofotometri UV-Vis
Authors: Kartika Irma , Anis Mhd. , Kartika Irma Ratna , Kurniadewi Fera
Published: June 2024

Food is one of human’s primary needs to survive and carry out their activities. Food must be safe, nutritious, and high quality when it’s consumed. In order to maintain food quality, some food ingredients, such as yellow noodles, crackers, and chicken, are often added with formaldehyde and borax, which are dangerous ingredients that are prohibited use as Food Additives (BTP) because their health hazards in accordance withRegulation of Minister Health No. 033 of 2012 and Regulation of BPOM No. 22 of 2023. Therefore, this research aims to identify qualitatively and determine the formaldehyde and borax levels quantitatively in yellow noodles, red crackers, and chicken as an effort to ensure the food safety. The method used in qualitative analysis is a rapid test kit and quantitative is UV-Vis spectrophotometry at a wavelength of 412 nm for formaldehyde and 551 nm for borax. The results of the qualitative analysis test showed that the yellow noodle sample contained formaldehyde and borax as indicated by the color change of the test stick to purple and red, respectively. Meanwhile, according to quantitative analysis, yellow noodles also contained formaldehyde and borax with average levels of 479.09 mg/kg and 44.43 mg/kg, respectively. Red crackers and chicken samples are free from formaldehyde and borax content.
Sentiment Analysis of Student Complaint Text for Finding Context
Authors: Dzulkarnain Anisa , Rahmy Lidiawaty Berlian , Hidayati Sri , Andi Hidayah Rafi , Pramesta Setyaningtitah Arini
Published: June 2024

Students are one of the users of services provided by institutions. Student complaint questionnaires were distributed to find out various complaints related to institutional services. The problem is how to interpret student complaints so that institutional services can be improved according to what is needed. Therefore, this research aims to analyze the sentiment of student complaints. Apart form that, this research also aims to find the context of each student's complaint regarding institutional services. This research uses sentiment analysis with Indonesian text. The method starts from data collection, data cleaning and labelling of complaints, pre-processing of complaint text, term frequency (TF) method used to extract the content, and accuracy measurement. The labeling process was carried out twice to compare the accuracy, precision, recall, and f1-score of the models. Based on the results of the sentiment analysis of student complaints, the accuracy rate reached 76.1%. Additionally, a precision of 65.2% and recall of 85.2% indicate that labeling is more balanced, although there is still room for improvement.
The State of Magnetic Axis Measurement of the Nica Collider Quadrupoles
Authors: Nikolaichuk I. Yu. , Borisov V. V. , Golubitsky О. М. , Zolotykh D. A. , Kondratiev B.
Published: June 2024

As part of the NICA megascience project the magnetic-cryostat system of the superconducting Collider is being assembled. The structural units of the Collider are 88 dipole and 82 quadrupole magnets of various configuration. In order to improve the accuracy of alignment of quadrupole magnets to the theoretical closed orbit of the beam in the Collider, it is necessary to measure the position of the magnetic axis in the coordinate system of the magnet. Vibration wire technique is used to perform such measurements in VBLHEP. The system operates at ambient temperature and allows measuring the position of the magnetic axis with an accuracy of ±0.053 mm. The article presents the design of the magnetic measurement system, an accuracy assessment is made and the current results of measurements of the position of the magnetic axis of the NICA Collider quadrupole magnets.
Development of the Available Technology Dressing: An Evidence-Based, Sustainable Solution for Wound Management in Low-Resource Settings
Authors: Benskin Richard , Benskin Linda
Published: June 2024

Background. Incapacitating wounds are common in rural areas of tropical developing countries. In this setting, injury and bite wounds often become chronic due to poor wound management. Objective. To summarize more than 20 years of research, culminating with testing the use of Available Technology Dressings (ATDs), a very specific sustainable moist dressing technique, which can be taught to patients and lay health care providers. Methods. Case studies, literature reviews, and qualitative and quantitative usual practice surveys provided the foundation for a 3-armed 12-week, evaluator-blinded, noninferiority RCT of the ATD technique. The ATD technique consists of (1) daily thorough wound irrigation, (2) protecting the periwound with a moisture barrier, (3) protecting the wound by conforming cut-to-fit thin food-grade plastic with slits to the wound bed, (4) fluffing absorbent material over the slits, and (5) holding the dressing in place (and, if possible, applying compression) with a snug wrap. ATDs were compared with saline-soaked wet-to-moist gauze (WTM, the negative control) and polymeric membrane dressings (PMDs, the positive control), evaluating safety, effectiveness, quality of life, pain, cost, dressing time, and acceptability in 40 Jamaicans with SCLUs. Results. Wound experts throughout rural areas of Ghana, Zambia, and Cambodia prefer moist wound management, but lack the tools to provide it consistently. Food-grade plastic outperforms all other improvised dressings. Thin plastic bags are affordable and available worldwide. In the RCT, ATDs (13 participants) outperformed WTMs (16 participants) and were only modestly inferior to PMDs (11 participants) for the parameters of wound size, pain, and safety. ATDs were the least expensive, most available, most acceptable choice. Conclusion. ATDs warrant further study.
Engineering Multisite Metal-Organic Cages with Metal Acyl Nodes for Specific Recognition and Deep Purification of Radioactive Strontium(II)
Authors: Jin Wei , Wu Qun-yan , Lou Yan , Huang Zhi-wei , Liu Feng , Hu Bo-wen , Yu Ji-Pan , Hu Kong-Qiu , Yuan Li-yong , Shi Wei-Qun , Mei Lei
Published: June 2024

Tailored design of organic linkers or metal nodes can implant desirable binding sites in metal-organic cages (MOCs) and greatly expand the type of guest they can encapsulate. In this work, we propose a feasible method of engineering acyl-type metal nodes, with a multisite anionic metal supramolecular cage (UOC) with uranyl nodes assembled with calix[4]resorcinarene linkers (C[4]R) as a prototype compound, to endow MOCs with selective recognition ability towards metal ions without compromising structural robustness of MOCs. In UOC, peroxide-bridged dimeric uranyl units on both sides of the coordination cage offer abundant coordination-available oxygen sites, creating a cryptand-like cavity that enables high-efficient recognition and encapsulation of Sr^(2+) ion due to precise size-matching effect. Bonding analysis of the resultant Sr@UOC suggest that, although electrostatic interaction predominates in host-guest interactions between UOC and Sr^(2+), there is significant degree of overlapping between Sr 4d and O 2p orbitals, thus conforming the origin of high binding strength of UOC for Sr^(2+). Meanwhile, hydrophobic binding cavities at both ends of UOC allow it to further encapsulate organic guests, thus facilitating co-inclusion of two different kinds of guest species in UOC for the first time. Inspired by the strong binding affinity of UOC to Sr^(2+), it is employed as absorbents to capture Sr^(2+) ion of low concentrations in aqueous solution. A removal efficiency of 99.9% could be achieved for Sr2+ ions at the initial concentration as low as 0.01 mM, with a record distribution coefficient (Kd) as high as 1.36×10^7 mL/g, demonstrating its huge potential for deep purification of trace amount of radioactive 90Sr^(2+).
Capacidades tecnológicas y ventajas competitivas, análisis bibliométrico
Authors: Estévez-Torres Ailen , Megna-Alicio Alexey , Lara Gómez Graciela , Valencia Pérez Luis Rodrigo
Published: June 2024

La investigación se centra en la revisión sistemática de la producción científica sobre capacidades tecnológicas como ventajas competitivas. Para ello, se utiliza como metodología el estudio bibliométrico de bases de datos internacionales como Scielo, Redalyc, Dialnet y DOAJ. Los resultados revelan que esta área es relativamente joven, pero creciente en importancia. Se destaca que la mayoría de los investigadores provienen de México y España, lo que refleja un interés particular en estas regiones. Finalmente, se identifican siete enfoques diferentes que demuestran la diversidad en las perspectivas de investigación, para lo cual se emplean herramientas como VOSviewer y Excel para un análisis riguroso y científico.
EDITORIAL
Authors: Rossinetti Rufinoni Priscila
Published: June 2024

Editorial do volume 09, número 18, ano 2020.
Importancia de la comunicación no verbal en el aula: actividades para la Educación Básica
Authors: Cedeño Salavarria María Patricia , Mendoza Arteaga María Yolanda
Published: June 2024

La presente investigación buscó profundizar en el entendimiento de las diversas manifestaciones y aplicaciones de la Comunicación No Verbal dentro del contexto de las aulas de Educación Básica. Para alcanzar este propósito, se optó por una metodología mixta, abordando el fenómeno desde múltiples ángulos: a través de entrevistas detalladas a docentes, quienes compartieron sus experiencias y perspectivas, y mediante observaciones in situ de estudiantes para examinar sus interacciones y comportamientos en el ambiente educativo. Los hallazgos del estudio arrojaron que la comunicación no verbal es un elemento omnipresente y vital en el proceso educativo. Docentes y estudiantes utilizan gestos, expresiones faciales, posturas, y variaciones en el tono y ritmo de voz para transmitir y recibir información, clarificar dudas, establecer relaciones de confianza y gestionar emociones. Además, se observó que las dinámicas no verbales tienen un papel crucial en cómo se configura el ambiente de aprendizaje, influyendo directamente en la receptividad y participación activa de los estudiantes. En base a estos resultados, se concluye que la comunicación no verbal, lejos de ser un complemento secundario, es una herramienta primordial en el proceso de enseñanza-aprendizaje, siendo esencial para profesores y alumnos reconocer, valorar y optimizar su uso para fortalecer la experiencia educativa.
Risk factors for healthcare-associated infections in intensive care units
Authors: Pereira Priscilla Perez da Silva , Sabini Andriely Alayne Carvalho , Deus Josimeire Cantanhêde de , Araújo Laís Xavier de , Pontes Daniela Oliveira , Hang Adriana Tavares , Souza Caren Juliana Moura de , Freitas Jeanne Lúcia Gadelha
Published: June 2024

Objetivo: Investigar os fatores de risco para infecções relacionadas à assistência entre pacientes internados em uma Unidade de Terapia Intensiva de uma capital do Norte do Brasil. Métodos: Estudo de coorte prospectiva, com 267 pacientes internados no período de 01 de outubro de 2017 a 30 de janeiro 2019. As informações foram coletadas de prontuário eletrônico, físico e padrão de acompanhamento dos pacientes. Investigaram-se informações demográficas sobre a internação e tratamento. Realizada regressão de Poisson para avaliação das variáveis com o desfecho. Resultados: A incidência de infecções foi de 10,49 casos por 100 pacientes, com a maior frequência para infecção de sítio cirúrgico. Na análise ajustada, internação por mais de cinco dias (RR: 6,98; IC95%: 1,42; 34,15), parada cardiorrespiratória (RR: 2,89; IC95%:1,05;7,96), ter ostomia (RR: 9,22; IC95%:1,47; 57,65) ou traqueostomia (RR: 10,23; IC95%: 1,56;67,22) foram associados às infecções relacionadas à assistência. Conclusão: A incidência de infecções encontrada foi superior às outras regiões brasileiras. Recomenda-se vigilância ativa, principalmente em pacientes com internação prolongada e ostomias, avaliação criteriosa da necessidade de dispositivos e uso de protocolos para adoção de boas práticas.
Contributions of educational technologies to the promotion of breastfeeding: integrative review
Authors: Anjos Flávia Lorena Henrique dos , Almeida Lidiane da Costa , Andrade Elaine Maria Rangel , Pereira Livia Carvalho , Souza Angel Alice Jácome de , Jorge Herla Maria Furtado
Published: June 2024

Objetivo: Analisar na literatura as contribuições das tecnologias educativas para a promoção da amamentação. Métodos: Revisão integrativa, com busca e seleção nas bases de dados CINAHL, Medline/PubMed, BDENF, Scopus e LILACS. Utilizaram-se os descritores Período Pós-parto; Tecnologias; Tecnologia Educacional; Aleitamento Materno; Enfermagem. Identificaram-se 1256 publicações que ao aplicar os critérios de elegibilidade resultaram na inclusão de 17 estudos primários, publicados nos idiomas português, inglês e espanhol, sem recorte temporal. A extração de dados foi realizada por meio de um instrumento validado e adaptado conforme variáveis de interesse. Resultados: A busca pela avaliação e implementação de tecnologias educacionais voltadas para promoção da amamentação levou ao desenvolvimento de ferramentas facilitadoras do processo de cuidado para capacitação profissional e apoio, suporte e orientação aos pais e familiares. Nesse sentido, foram identificados diferentes recursos tecnológicos que contribuíram para o aprimoramento do conhecimento e de habilidades, assim como maior segurança materna e infantil. Conclusão: As tecnologias educacionais constituem métodos promissores e revolucionários para o desenvolvimento das práticas de cuidados, como a amamentação, representando ferramenta de apoio aos profissionais, pacientes e familiares por permitir a troca de informações, monitoramento de casos e ganho de conhecimento.
Impact of the COVID-19 pandemic on excess risk of dying – Brazil, 2020
Authors: Silva Neylany Raquel Ferreira da , Sousa Carliane da Conceição Machado , Rodrigues Malvina Thais Pacheco , Mascarenhas Márcio Dênis Medeiros
Published: June 2024

Objetivo: Analisar o impacto da pandemia de COVID-19 no excesso do risco de morrer no Brasil em 2020. Métodos: Estudo ecológico do tipo exploratório, com dados de óbitos por todas as causas de morte do Painel de Monitoramento da Mortalidade do Ministério da Saúde. Calcularam-se taxas brutas e razões de taxas (RT) de mortalidade por todas as causas segundo os capítulos da causa básica de morte, sexo e faixa etária. Verificou-se associação estatística por meio do teste qui-quadrado de Mantel Haenszel quando p<0,05. Resultados: Houve aumento no risco de morrer de 13% em 2020. As regiões com maior incremento na taxa de mortalidade foram Norte (RT=1,24; IC95%: 1,23-1,26), Centro-Oeste (RT=1,17; IC95%: 1,16-1,18) e Nordeste (RT=1,15; IC95%: 1,14-1,15). O excesso no risco de morrer foi maior no sexo masculino, na região Norte, por doenças infecciosas e parasitárias, incluindo a COVID-19 (RT=4,58; IC95%: 4,53-4,62), seguida de causas mal definidas (RT=1,33; IC95%: 1,32-1,34), gravidez, parto e puerpério (RT=1,17; IC95%: 1,10-1,25). Conclusão: O excesso de risco de morrer possibilitou reconhecer a magnitude e o impacto da COVID-19 no país e pode subsidiar as autoridades de saúde na organização de ações voltadas para a diminuição dos efeitos dessa emergência de saúde pública.
Children with rare diseases: maternal experiences and challenges
Authors: Souza Iris Caliane Coelho de , Melo Mônica Cecília Pimentel de , Santos Ana Dulce Batista dos , Morais Ramon José Leal de
Published: June 2024

Objetivo: Analisar vivências e desafios de mães mediante a revelação do diagnóstico para anomalias congênitas. Métodos: Pesquisa qualitativa, exploratória e descritiva, desenvolvida no município de Dormentes, Estado de Pernambuco, Brasil, em Unidades Básicas de Saúde, através da entrevista semiestruturada, com 8 mães que receberam o diagnóstico para anomalia congênita durante o pré-natal ou pós-nascimento, ocorrida entre 2017 e 2022. Utilizou-se uma amostra não probabilística, por intencionalidade, com fechamento amostral por exaustão. Os dados coletados foram analisados a partir da técnica da análise temática de conteúdo. Resultados: As mães ao vivenciarem o diagnóstico experimentam medo, tristeza e luto. A revelação do diagnóstico implica em adaptações que envolvem toda a família, na qual, os desafios postos, ao receber a notícia, evidenciaram a importância do acolhimento, do esclarecimento do diagnóstico e apontaram para busca de informações e da religiosidade, como dispositivos de fortalecimento.  Conclusão: Os achados desvelaram os processos adaptativos das famílias, principalmente das mães, apontando sobretudo para a necessidade de os profissionais, em específico, da enfermagem, repensarem seu papel alicerçado na empatia e na humanização, buscando o empoderamento das famílias para se adaptar ao novo, encorajando-as a vivenciarem o processo.
Safe use of medications: learning needs and strengths for teaching mediated by virtual technologies
Authors: Figueiredo Iolanda Gonçalves de Alencar , Pierot Esteffany Vaz , Avelino Fernanda Valéria Silva Dantas , Navarro Fabiola Jazmin Caceres , Leal Loisláyne Barros , Negreiros Ana Luiza Barbosa
Published: June 2024

Objective: To identify the learning needs of undergraduate nursing students about patient safety and medication safety. Methods: Descriptive and cross-sectional study, developed from March 2019 to December 2020, with a non-probabilistic and intentional sample consisting of 45 undergraduate nursing students. Data were analyzed using descriptive statistics. Results: There was a predominance of female students (73.3%) with family income between 1 and 2 minimum wages. All confirmed having access to the internet, with a daily frequency of use by participants (93.3%). The smartphone was the most used device to access the internet (77.8%), with the home being the predominant place of access (80.0%). Regarding the learning needs about patient safety and medication safety, the classification “essential” stood out among the evaluated questions. Conclusion: The main identified learning needs of the participants were: working effectively as part of a team, understanding the systems and the effect of the complexity of patient care and defining the key concepts. In addition to that, there were weaknesses in differentiating between common terms in the medication administration process.
Evidence-based practice: incorporating research into clinical practice
Authors: Lopes-Júnior Luís Carlos
Published: June 2024

Evidências Científicas (ECs) configuram-se como “resultados de pesquisas científicas”, realizadas através de procedimentos que incorporaram critérios de validade, isto é, viabilidade (F-feasibility), adequação (A-appropriateness), significado (M-meaning) e efetividade (E-effectiveness) das práticas de saúde, levando-se em conta todas as possíveis fontes de vieses(1). O termo Prática Baseada em Evidências (PBE) foi cunhado entre as décadas de 70 e 80, sendo originário do movimento da Medicina Baseada em Evidências (MBE), quando foi proposta uma hierarquia dos níveis de ECs, de modo a direcionar a busca das melhores ECs disponíveis para a tomada de decisões na prática clínica(2). No ano de 2002, enfermeiras engajadas na prática clínica e em pesquisa estabeleceram um modelo para implementação da PBE, o “Advancing Research and Clinical Practice through Close Collaboration (ARCC)”, com o intuito de aprimorar e melhor integrar a pesquisa à prática clínica, atrelando aos cuidados de saúde locorregionais e nacionais(3).
Assim, a PBE consiste em uma abordagem ancorada na resolução de problemas para prover o cuidado em saúde que integra as melhores ECs disponíveis provenientes de estudos bem delineados, e combina com as preferências e valores do paciente e a expertise do profissional de saúde. Para a implementação da PBE na prática clínica, é preciso que o profissional de saúde mantenha a atitude questionadora de modo a transformar a prática clínica(3). O fio condutor da PBE é a utilização de resultados de pesquisas na prática. Nesse sentido, o movimento de Enfermagem Baseada em Evidências emerge como um elo que interliga as melhores ECs e sua aplicação na prática clínica, primando pela tomada de decisão para um cuidado cientificamente qualificado e seguro(1). Na prática do enfermeiro, a aplicação da PBE consiste em sete passos: 1) elaboração da questão clínica; 2) busca de ECs; 3) avaliação crítica das ECs recuperadas no processo de busca; 4) tomada de decisões com base nas melhores  ECs; 5) avaliação dos resultados da decisão clínica a ser implementada; 6) mudanças com base nas ECs disponíveis; 7) disseminação dos resultados da decisão clínica/mudança da práxis(3).
 
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Construction and validation of indicators to evaluate the implementation of the kangaroo method using the Delphi technique
Authors: Cândido Joice Luiza Alves , Frias Paulo Germano de , Sarinho Silvia Wanick
Published: June 2024

Objective: To present the validation process of a matrix of indicators to evaluate the implementation of the second and third stages of the Kangaroo Method (KM) in two reference maternity hospitals and in primary care in Recife. Methods: The construction and validation process followed four stages: (1) elaboration of the logical model of the 2nd and 3rd stage of the KM; (2) composition of the preliminary indicator matrix; (3) selection of experts, sending indicators to this group for analysis using the Delphi Technique; (4) consolidation of results and sending to experts for second consultation and final analysis. A Content Validity Index (CVI) equal to or greater than 80% was adopted to establish agreement. Results: The logical model was composed of components for the 2nd and 3rd stages of the KM, with the Education and Care subcomponents, and a component for the interface of the two stages, with the Management subcomponent. Of the 110 items presented, two did not present consensus in the first round and three suggestions for changes were made. Five new indicators were included, totaling 113 indicators at the end. Conclusion: The use of the Delhi technique made it possible to expand the consensus and validate the KM...
Reduction in life activities after hospitalization for COVID-19 in intensive care units
Authors: Martins Hevelyn Mayara Traleski , Amaral Ianka do , Souza Thayná Kimberly Pereira de , Duarte Carolina Ribeiro , Schiochet Gabriela Fernanda , Fadel Cristina Berger , Santos Celso Bilynkievycz dos
Published: June 2024

Objective: To verify the factors associated with reduction in life activities in patients 12 months after discharge from the COVID-19 ICU. Methods: This is a cross-sectional, analytical study with a quantitative approach, based on primary data from patients at the Hospital Universitário Regional dos Campos Gerais, Paraná, Brazil. The final sample consisted of 32 patients discharged from the ICU between March 2020 and March 2021. Results: There was statistical evidence of a difference between the means of the groups in the domains Life Activities (p= 0.0001) and Disability (p< 0.0001), confirming that the disabled group has a worse indicator of disability in this domain; as also occurs between the geometric means of the groups. Conclusion: The most prevalent factors associated with reduction in life activities were those involving the physical and psychological domains, directly influencing their recovery. In addition, future research could focus on specific intervention strategies to minimize the impact of these sequelae and improve rehabilitation in COVID-19 patients.
Physicians' knowledge, attitude and practice about reporting work-related accidents in primary care
Authors: Souza Júnior Otenberg Nogueira de , Benevides Bruno Souza , Araújo Márcio Flávio Moura de , Nuto Sharmênia de Araújo Soares , Barros Lívia Moreira , Guimarães Samuel Carvalho , Freire de Freitas Roberto Wagner Júnior
Published: June 2024

Objective: To evaluate physicians' knowledge, attitude and practice (KAP) on Work-related Accident Reports (Comunicações de Acidentes de Trabalho, CATs) in Primary Care. Methods: A cross-sectional study carried out from November 2020 to January 2021, with application of the Survey to 229 physicians from Fortaleza, Ceará. The instrument was sent electronically with questions about knowledge, attitude and practice in relation to the CAT. The project was approved by a Research Ethics Committee under opinion No. 4.263.48. Results: The highest inadequacy rate was related to practice (85.59%). Inadequate knowledge was associated with the existence of different forms of medical employment (p=0.04), inadequate practice (p<0.001) and inadequate attitude (p=0.009). Inadequate attitude was associated with inadequate practice (p=0.026) and inadequate knowledge (p=0.009). Furthermore, 88.21% of the participants (n=202) stated that they had never filled in the CAT. Inadequate practices were associated with inadequate knowledge (p<0.001) and inadequate attitude (p=0.026). Conclusion: The physicians' knowledge, attitude and practice in relation to the CAT need to be improved.