bluuebunny/crossref_metadata_2025 huggingface dataset:
Discusión sobre el espacio didáctico del laboratorio contable en la educación superior
Authors: Rincón Soto Carlos Augusto , Molina Mora Francisco Ricardo , Solano Rodríguez Omar Javier , Lemos De la Cruz Jorge Eduardo
Published: July 2023

En el campo de la contabilidad, el laboratorio contable ha ganado relevancia como un espacio para desarrollar competencias prácticas e investigativas de los estudiantes, fundamentales para su desempeño profesional. Sin embargo, es importante reflexionar sobre la naturaleza y objetivos de este laboratorio, evitando que se convierta en una práctica técnica. Este artículo se enfoca en analizar el papel del laboratorio contable y examinar su sentido en la formación de profesionales contables, así como revisar críticamente prácticas equivocadas en su implementación.  El artículo adopta un enfoque interpretativo, conceptual y reflexivo, buscando evaluar el propósito y la esencia del laboratorio contable, y proporcionar elementos conceptuales para reevaluar y mejorar su enseñanza. Se abordan temas como las diferencias desde la educación basada en competencia entre el espacio educativo de la educación tecnológica y profesional en contabilidad. Los resultados muestran las diferencias existentes en los espacios educativos de los laboratorios y talleres contables.
Riesgo financiero e incertidumbre en los mercados bursátiles en tiempo de covid-19: un análisis bibliométrico
Authors: Ramos Zambrano Housseman Steven
Published: July 2023

El presente artículo tiene como objetivo explorar el riesgo financiero durante la época de pandemia en los mercados bursátiles. Para ello, se recopila, depura y analiza 252 documentos de la base de datos de Scopus, entre 2019 a 2022, bajo una metodología teórico-exploratoria con la que se elabora un análisis de redes, desde de la teoría de grafos con Rstudio (Bibliometrix), VOSviewer y Tree of Science. Los resultados indican una tasa de crecimiento del conocimiento anual del 33,4%, donde China y Estados Unidos han generado mayores investigaciones. Se identificó en los clústeres elaborados, tres áreas de trabajo: una descriptiva con nivel estadístico y matemático bajo, la segunda con un nivel medio de análisis relacionada con estudios de riesgo sistemático, estabilidad financiera y administración de riesgo y la última, con un alto desarrollo analítico de investigación que han intentado dar explicación del efecto del COVID-19 en los mercados financieros. Finalmente, se concluye que los países requieren establecer procesos continuos de información respecto a estos tipos de impacto, ya que estudios previos han demostrado que regiones emergentes son muy susceptibles ante las permutaciones que sufren las regiones de alto desarrollo económico.
Examination of The Attitudes of The Students of The Faculty of Sports Sciences Towards Rhythm Education and Dance Lesson
Authors: ÇİNGÖZ Yunus Emre , ÇAKIR Zekai
Published: July 2023

The importance of dance and rhythm education is increasing day by day, especially for students studying in the field of sports sciences. This study aims to adopt a more effective and inclusive approach in sports science education by shedding light on students' attitudes toward rhythm education and dance lessons and providing guidance for faculty members and administrators to improve the delivery and content of these courses. The relational screening model, one of the general screening models, was used in the research. Personal information forms prepared by the researchers and the "Attitude towards Rhythm Education and Dance Lesson Scale-ATREDLS" were used as data collection tools. SPSS 26.0 package program was used in the analysis of the data. Descriptive statistical methods (number, percentage, mean, standard deviation) were used to evaluate the data. Parametric tests were used because it was determined that the data showed normal distribution after the skewness, and kurtosis tests were performed to determine whether the data showed a normal distribution. Frequency, percentage distribution, and mean values were used in the data analysis; an independent sample t-test was used to compare the continuous quantitative data between two independent groups, and a single-factor analysis of variance ANOVA analyses were used to compare the constant quantitative data between more than two independent groups. In physical education and sports, the rhythm of movements is essential in teaching and controlling sports skills.
THE ROLE OF ANAK JALANAN AT-TAMUR ISLAMIC BOARDING SCHOOL IN INTERNALIZING THE VALUES OF RELIGIOUS MODERATION TO COLLEGE STUDENTS IN BANDUNG
Authors: Yusuf Muhamad , Alwis Alwis , Putra Eka , Witro Doli , Nurjaman Andri
Published: July 2023

The emergence of the concept of religious moderation initiated by the Ministry of Religion of the Republic of Indonesia and set forth in the 2020-2024 National Medium-Term Development Plan (RPJMN) indicates that the program for internalizing and strengthening the values of religious moderation is very important and urgent to implement. The values of religious moderation consist of four points, namely national commitment, tolerance, anti-radicalism, and accommodative to local culture. The direction to internalize the four values of religious moderation is also played by the Anak Jalanan At-Tamur Islamic Boarding School, Bandung. This article aims to reveal the role of the Anak Jalanan At-Tamur Islamic Boarding School in internalizing the values of religious moderation to students. This article uses qualitative research methods that are field research. The research data were obtained from two sources, namely field data sources and library data sources. Data collection techniques used are observation, interviews, and documentaries. The data analysis techniques used are data condensation, data presentation, and drawing conclusions. The results showed that success in internalizing the values of religious moderation to students could be seen from the indicators or values of religious moderation. The four indicators (values) of religious moderation are reflected in the routine activities and attitudes of students of the Anak Jalanan At-Tamur Islamic Boarding School. Commitment to nationalism, tolerance, anti-radicalism and accommodativeness to local culture is imprinted in the personalities of the students of the Anak Jalanan At-Tamur Islamic Boarding School. This is also due to two things: firstly, interfaith dialogue events are often held and secondly, the leader of the Anak Jalanan At-Tamur Islamic Boarding School who has a broad and open view and emphasizes morality in his education.
Appraisal of biomedical waste management practice in India and associated human health and environmental risk
Authors:   Department of Community Medicine and School of Public Health, Post Graduate Institute of Medical Education and Research, Chandigarh-160 012, India, Ravindra K. , Sareen A. ,   Department of Community Medicine and School of Public Health, Post Graduate Institute of Medical Education and Research, Chandigarh-160 012, India, Dogra S. ,   Chandigarh Pollution Control Committee, Chandigarh-160 019, India, Mor S. ,   Department of Environment Studies, Panjab University, Chandigarh-160 014, India
Published: July 2023

Biomedical waste management is an essential aspect of human and environmental safety. The healthcare industries and the unfortunate pandemic have increased the generation of biomedical waste. If biomedical waste is not managed safely, it poses human health and ecological risks. Hence, the study aims to appraise the scenario of biomedical waste management in India and to identify its effect on human health and the environment. The study used a systematic approach to review all the rules and regulations related to biomedical waste management issued by the Government of India from time to time. Further, the study explored the strengths and weaknesses of the current BMW management rules using the SWOT analysis model. All recent and relevant literature was critically examined using scoping review approaches to better understand the health and environmental risks associated with poor biomedical waste management to propose the best practices and future direction. It was found that needle stick injury is a major hazard to human health during segregation. Poor segregation practices can lead to the mixing of biomedical waste with municipal solid waste. Hence, there is a need for proper training about the current biomedical waste rules with a specific focus on biomedical waste segregation at the time of generation. Each process involved in biomedical waste management can adversely impact the environment and human health if not managed well. The impact and gaps of poor biomedical waste management from generation to disposal have been identified. The study recommends routine awareness programs and capacity building for proper biomedical waste management and to minimize the associated environmental and human health risks. These risks could be minimized further through implementing scientific and systematic approaches in biomedical waste treatment and management, including regulatory compliance.
Kinetics of biomass and polyhydroxyalkanoates synthesis using sugar industry waste as carbon substrate by Alcaligenes sp. NCIM 5085
Authors:   Department of Chemical Engineering, Government Engineering College, Bhuj-370 001, India, Kanzariya R. , Gautam A. ,   Department of Chemical Engineering, Shroff SR Rotary Institute of Chemical Technology, Ankleshwar-393 135, India, Parikh S. ,   Department of Chemical Engineering, Department of Technical Education, Gandhinagar-382 424, India, Gautam S. ,   Department of Chemical Engineering, Shroff SR Rotary Institute of Chemical Technology, Ankleshwar-393 135, India
Published: July 2023

Aim: o optimize the operating parameters and further determine the kinetics of biomass and polyhydroxyalkanoate synthesis using sugar industry waste as a carbon substrate by Alcaligenes sp. NCIM 5085. Methodology: Molasses, clarified and pretreated with sulphuric acid, was taken in a batch reactor for fermentation to generate biomass and further for polyhydroxyalkanoate synthesis where Alcaligenes sp. NCIM 5085 was used as a culture. A number of parameters were observed during fermentation experiments to optimize the biomass and PHA namely: initial substrate concentration, incubation period, C/N ratio, inoculum concentration and pH. Fermented solution was filtered to account the yield of biomass from the solution at each time interval decided for each experiment and polyhydroxyalkanoate was extracted from the biomass by chloroform and methanol extraction. Growth kinetics of biomass was modeled by Monod and Logistic models whereas Luedeking-Piret model was used for polyhydroxyalkanoate production rates. Results: From the fermentation experiments, it was found that for 40 g l-1 of molasses at neutral pH, 4.48 g l-1 of biomass was synthesized when fermentation was observed for 48 hr. One percent of cell dry weight of biomass was extracted as polyhydroxyalkanoate. Logistic model for growth kinetics and Luedeking-Piret model for polyhydroxyalkanoate production rate were found in agreement with the experiments where regression coefficient was maximum with minimum error. Interpretation: The PHA growth kinetics and PHA production kinetics done in this work can be utilized to design a bioreactor for PHA production at industrial scale. Key words: Alcaligenes sp., Biomass, Cane molasses, Growth kinetics, Polyhydroxyalkanoates
Educación ambiental vivencial: Taller sobre el valor de las aves silvestres para promover actitudes y conductas positivas en estudiantes de la Escuela rural La Cataluña, Tacares, Alajuela, Costa Rica
Authors: Henry Alejandro Enríquez Mora  , María Celeste Méndez Mesén  , Erik Tomás Montiel Mendoza  , Brithany Morales Conejo  , Héctor Perdomo Velázquez
Published: July 2023

Cataluña es una comunidad rural de Costa Rica, dedicada principalmente a la agricultura local. Su contexto ambiental cuenta con una gran biodiversidad de fauna silvestre, que incluye aves como el tucán pico iris, el carpintero lineado, y la lapa roja, entre otras. Durante la temporada de anidación de estas aves, los hombres adultos se dedican a capturar polluelos para venderlos. Además, está normalizado entre niños y adultos el matar aves, así como otros animales, como forma de entretenimiento. Como proyecto de un curso de Educación Ambiental de la Universidad de Costa Rica, se realizó un taller con niños de quinto grado de la Escuela La Cataluña. El objetivo fue promover actitudes y conductas positivas hacia las aves silvestres, por medio de sensibilización y aporte de conocimientos. El taller consistió en un ejercicio vivencial en el que se observaron e identificaron aves que visitan la escuela, además de impartir una charla sobre los valores y servicios ambientales que aportan las aves silvestres a la comunidad. Para evaluar el taller, los niños realizaron dibujos mediante los cuales pudieron identificar mayores conocimientos y actitudes positivas con respecto a las aves silvestres. Se considera que la iniciativa podría influir también en las actitudes y conductas de los adultos.
Medidas para la reducción del riesgo de contaminación ambiental con residuos de antibióticos y propagación de bacterias resistentes
Authors: Adriana Villalobos Araya  , Sandra Estrada-König  , Andrea Chaves Ramírez  , Josué Rivera-Castillo  , Fabio Chaverri-Fonseca  , Gustavo Gutiérrez-Espeleta  , Kinndle Blanco-Peña
Published: July 2023

La contaminación ambiental con antibióticos y la propagación de bacterias resistentes pueden provocar daños a la salud, el surgimiento de nuevas pandemias, la alteración del equilibrio de los ecosistemas, la inseguridad alimentaria y una crisis económica mundial. Ante este contexto, se plantea un análisis documental de las causas y consecuencias del problema, con el propósito de proponer medidas para la reducción de los riesgos. Como resultado de la investigación, se plantea el abordaje de la problemática a partir del enfoque “Un mundo, una salud”, donde es fundamental la implementación de buenas prácticas para la prevención de enfermedades infecciosas y el uso óptimo de antibiótico sen la salud humana, animal y vegetal. Esto debe estar acompañado de procesos de investigación y concientización social, participación ciudadana, incidencia y gestión política, que permitan conservar un ambiente sano y ecológicamente equilibrado.
La diversidad taxonómica y la red de interacción especie-hábitat son elementos clave en un enfoque de paisaje para la conservación de artrópodos en un bosque seco de Costa Rica
Authors: Leonardo Vilas-Bôas M.P. de Cerqueira
Published: July 2023

Al tomar decisiones sobre cuáles áreas deben ser preservadas e incluidas en planes de gestión de parques, bosques y otras áreas importantes para la conservación de la biodiversidad, es crucial tener en cuenta la diversidad de hábitats y especies presentes. Sin embargo, es común no considerar las interacciones entre los diferentes elementos del ambiente ni reconocer la importancia de entender un sitio específico como un ecosistema integrado. Para evaluar la estructura de las comunidades de artrópodos, se empleó un diseño de paisaje y dos enfoques: el enfoque de diversidad taxonómica y el enfoque de análisis de redes de interacción. Se investigaron los efectos de la composición del paisaje en la diversidad verdadera, la diversidad beta y la interacción entre paisajes y especies. Se llevó a cabo el estudio en Palo Verde, uno de los últimos remanentes de bosque seco de Costa Rica. Se muestrearon 399 individuos de 34 morfotipos de artrópodos. A escala de paisaje, los resultados destacan la relación positiva entre la vegetación densa y la diferencia entre el porcentaje de vegetación moderada entre paisajes con la diversidad de especies dominantes y la diversidad beta y el recambio de especies de artrópodos, respectivamente. Los resultados indican que aquellos que cuentan con una mayor diferencia de vegetación moderada pueden ser más heterogéneos y, por tanto, más efectivos en la conservación de la biodiversidad de artrópodos en los paisajes de Palo Verde; además, una mayor proporción de vegetación densa contribuye a mantener comunidades diversas, estables en términos de  dominancia de especies y mayor conectividad con otros paisajes.
Fauna silvestre atropellada en la Ruta Nacional 21: ¿cuáles especies están en riesgo en el cantón de Carrillo, Guanacaste?
Authors: Henry Abarca Morales
Published: July 2023

La provincia de Guanacaste ha sido objeto de un aumento en el desarrollo inmobiliario y de su red vial. El aumento de las calles nacionales y cantonales han fragmentado el hábitat y cambiado la dinámica natural de los ecosistemas y de sus poblaciones silvestres. El tránsito vehicular a través de la Ruta Nacional 21 en el cantón de Carrillo ha generado un impacto negativo en aves, mamíferos silvestres y especialmente en la herpetofauna.
Recuento de las nuevas especies de árboles descubiertas en Costa Rica entre 2000 y 2022
Authors: Diego Aguilar-Sandí
Published: July 2023

La exploración botánica que se ha realizado en Costa Rica ha sido intensa. Sin embargo, el conocimiento sobre la riqueza total de especies que componen la flora del país dista mucho de haberse completado. En este artículo se presenta un recuento, a partir de una revisión bibliográfica, de las nuevas especies de árboles que fueron descubiertas en Costa Rica entre 2000 y 2022. Esto con el fin de exponer de forma sucinta los avances que se han realizado en materia de diversidad de árboles en este país en lo que va del siglo XXI. Las fuentes se localizaron mediante los motores de búsqueda de las bases de datos DOAJ, JSTOR, SciELO, SpringerLink y Web of Science. Además, se revisó el boletín The Cutting Edge. Se encontraron 115 fuentes en las que se describieron 191 especies nuevas de árboles de 81 géneros y 39 familias de angiospermas. Los descubrimientos ocurrieron durante todos los años del período analizado y quedaron distribuidos por todo el territorio del país, incluyendo la Isla del Coco. Con base en la información recabada, se puede afirmar que el trabajo taxonómico realizado en Costa Rica ha sido constante y que el conocimiento sobre el número de especies de árboles presentes en el país ha aumentado año tras año.
Nuevas funciones en la evaluación de los aprendizajes aplicados en la asignatura de SIG y agromática, durante el Covid-19
Authors: Álvarez Garay Benjamín , Mora Jiménez Christopher
Published: July 2023

En el contexto de la pandemia del Covid-19, se inició un proceso de análisis bajo una línea de abordaje acorde con los términos de evaluación del aprendizaje para la enseñanza de la asignatura de Sistemas de Información Geográfica (SIG) y agromática. La agromática se apoya en una serie de ventajas ligadas al uso de las Ciencias de Información Geográfica (CIG), como el acceso a información remota de los sistemas agroproductivos, la construcción de geodatos y la interacción de distintas Infraestructuras de Datos Espaciales (IDE) ligadas a la integración de información geográfica.

En las lógicas de evaluación se integran los universos sugeridos para el manejo de geodatos, con los cuales se establecen nuevas funciones para fomentar en la estimación de los aprendizajes. La agromática se apropia de métodos para el análisis de dinámicas productivas, a partir de los universos se reconocen los argumentos facilitadores para la toma de decisiones con respecto a la funcionalidad que deben cumplir las evaluaciones.

La sistematización realizada de los resultados de entregas finales, con las experiencias desarrolladas por el estudiantado, es una revisión entre el año 2020 hasta el primer periodo del año 2022. Los resultados son aplicados al contexto productivo, lo que determina dos momentos en el aprendizaje de la agromática: modelar escenarios productivos a partir del uso de geodatos y el consecuente análisis espacial.

Con las experiencias surgidas con la entrega de los trabajos de los estudiantes, se comprueban las habilidades en el manejo de información geográfica sobre contextos productivos y la capacidad formativa integrada en el proceso de evaluación.
Implicaciones y requisitos para la implementación de un gobierno corporativo, como ventaja institucional para la cadena de valor del sector cooperativista costarricense
Authors: Burgos-Camacho María José
Published: July 2023

El gobierno corporativo nace ante la crisis de Wall Street, creando la necesidad de que los tomadores de decisiones respondan a los accionistas por sus prácticas de negocios, siendo así se elaboró un estudio cualitativo al sector cooperativista costarricense por medio de un muestreo de experto sobre los factores predominantes para la implementación de gobierno corporativo y que mediante la alternativa metodológica alcanzable, propuesta por Pablo Cáceres, se detectó que existe una diferenciación potestativa del legislador costarricense para supervisar los controles monetarios de las cooperativas, lo que implica una desventaja en cuanto a la presencia de estructura de regulación y fiscalización robustas y actualizadas.
Structural equation modeling of commitment in the COVID-19 era
Authors: García-Lirios Cruz , Bermudez-Ruiz Gilberto , Sanchez-Sanchez Arturo
Published: July 2023

Work commitment is an observable process in times of crisis or job stability. Given that the structure of work commitment is influenced by various dimensions observed during the pandemic, the aim of this study was to demonstrate its structure of mediating relationships. For this purpose, an exploratory, cross-sectional, and psychometric study was conducted with a sample of 100 students. Once the factorial structure was explored, a second study was carried out to confirm the structure using another sample of students. The selection criteria were related to inclusion in professional internships and community service in community centers. The results indicate that the fit and residual parameters suggest the non-rejection of the null hypothesis regarding significant differences between the theoretical structure and empirical observations. In relation to paradigms, it is assumed that extending the model would be relevant in order to predict job performance.
Towards More Specific Personality Research in Entrepreneurship: Relating Conscientiousness Facets to Venture Performance
Authors: Conejo Francisco J. , Khuntia Jiban , Parthasarathy Madhavan
Published: July 2023

Purpose. The literature has long recognized the importance of the conscientious entrepreneurial personality. This study explores how seven of its facets/sub-dimensions (Achievement-Striving, Efficiency, Responsibility, Industriousness, Self-Control, Conventionality, and Persistence) relate to three performance outcomes (Ventures Started, Years at Current Venture, and Annual Sales.)Design/methodology/approach. 166 active entrepreneurs were surveyed via an entrepreneurship center at a Western US university. Data was then modeled via Ordinary Least Squares to obtain regression estimates for the dependent variables.Findings. Counter to expectations, results indicate that facet measures relate very differently in terms of magnitude, direction, and significance to the performance outcomes. These more nuanced relations are lost when using broad/aggregate dimensional measures.Research implications. Broad personality measures, as conventionally used, are suboptimal for entrepreneurial research as they potentially yield misleading results. Studies should instead apply the more-specific facet measures, which offer more accurate personality assessments. Practical implications. Practitioners should also use the more-specific facet measures. Doing so will be of value across a variety of public, private, and educational settings.Originality/Value. For decades, entrepreneurship has addressed the effects of broad/aggregate personality dimensions. This article is the first to approach the entrepreneurial personality from a more-specific facet level, an approach offering substantial research opportunities.
Creación del marco regulatorio para Fintech en Costa Rica
Authors: Oconitrillo Rojas Andrea
Published: July 2023

Este artículo describirá los elementos de la hoja de ruta FinTech que las Superintendencias, el Consejo Nacional de Supervisión del Sistema Financiero (CONASSIF), y el Banco Central de Costa Rica (BCCR), han venido implementando para el diseño de un marco regulatorio para FinTech en el país. Se prestará especial atención al recientemente creado "Centro de Innovación Financiera (CIF)" y a la descripción de una posible visión de futuro.
Las opiniones y puntos de vista aquí expresados son los de la autora y no reflejan necesariamente la posición oficial de ninguna de sus instituciones asociadas.
DIRECTIVE ILLOCUTIONARY ACTS IN JAPANESE MOVIES
Authors: Adnjani CH Ghaisani , Mulyadi  , Syafitri Handayani Diah
Published: July 2023

This study aims to describe the meaning of directive illocutionary speech acts in the Japanese movie entitled Peach Girl and Miseinen Dakedo Kodomo Janai. The directive illocutionary act is the most frequently used speech act in everyday life. In Japanese, the meanings of these speech acts are often misinterpreted so the meaning of the speech isn’t conveyed properly. Peach Girl and Miseinen Dakedo Kodomo Janai use a lot of directive illocutionary speech acts, so a deeper study is needed regarding the meaning of directive speech act. The theory used in this research is speech act theory by Searle (1979). This study used descriptive qualitative method. The results found that there are 10 meanings of directive illocutionary speech acts, namely 1) command, 2) order, 3) beg, 4) request, 5) invitation, 6) deny, 7) advise, 8) prohibition, 9) warn, and 10) ask.
Establishing Surrogate markers by Consensus for Antepartum and Intrapartum Stillbirth: The In-utero Consensus for Alternative outcomes in Research on Stillbirth (ICARES) project
Authors: Gordijn Sanne , Papageorghiou Aris , David Anna , Ali Sam , Ganzevoort Wessel
Published: July 2023

Intervention bias refers to a systematic difference in management or
variable exposure among subjects in studies, which can significantly
influence outcomes.
Unveiling the Abundance and Composition of Rhizobacterial Communities Associated with Halophytic Plants in Gujarat, India
Authors: Nigam Kratika , Padhiyar Shital , Bhatt Shraddha , Kheni Jasmin , Vala Ashish , Rajyaguru Riddhi , Tomar Rukam Singh
Published: July 2023

Halophytes are a group of plants that possess the ability to withstand a
broad range of salinity levels, extending even beyond the concentration
found in seawater. Soil salinity can indirectly impact plant development
but this effect can be minimized by the activities of beneficial
bacteria residing in the rhizosphere of halophytic plants. This research
undertaking employed next-generation sequencing technology to examine
the rhizobacteria associated with the roots of five distinct halophytic
plant species. By utilizing 16S rRNA gene amplification, the findings
unveiled the prevalence of bacterial members belonging to the phyla
Proteobacteria, Actinobacteria, Bacteroidetes, Igvanibacteriae,
Chloroflexi, Nitrospirae, Cyanobacteria, and Firmicutes, with
Proteobacteria being the most abundant phylum. Furthermore, a
comparative analysis was conducted to explore the existence of diverse
bacterial communities associated with halophytic plants at the species,
genus, and family levels. This study conducted in the Saurashtra region
of Gujarat offers valuable insights into the species that contribute to
the maintenance of biogeochemical cycles within the ecosystem.
Additionally, it facilitates the identification of plant
growth-promoting, halotolerant bacteria, which can potentially enhance
the salinity tolerance of non-halophytic crops. Notably, this study
represents the first metagenomic investigation conducted on the
rhizosphere of any halophytic plant species from the Gujarat region of
India.
Endoglin ER-retained mutants exacerbate loss of function in hereditary hemorrhagic telangiectasia type 1 (HHT1) by exerting dominant negative effects on the wild type allele
Authors: Ali Bassam R. , Gariballa Nesrin
Published: July 2023

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant
disorder affecting 1 in 5,000-8,000 individuals. Hereditary hemorrhagic
telangiectasia type 1 (HHT1) is the most common HHT and manifests as
diverse vascular malformations ranging from mild symptoms such as
epistaxis and mucosal and cutaneous telangiectases to severe
arteriovenous malformations (AVMs) in the lungs, brain or liver. HHT1 is
caused by heterozygous mutations in the ENG gene, which encodes
endoglin, the TGFb homodimeric coreceptor. It was previously shown that
some endoglin HHT1-causing variants failed to traffic to the plasma
membrane due to their retention in the endoplasmic reticulum (ER) and
consequent degradation by ER-associated degradation (ERAD). Endoglin is
a homodimer formed in the ER, and we therefore hypothesized that mixed
heterodimers might form between ER-retained variants and WT protein,
thus hampering its maturation and trafficking to the plasma membrane
causing dominant negative effects. Indeed, HA-tagged ER-retained mutants
formed heterodimers with Myc-tagged WT Endoglin. Moreover, variants
L32R, V105D, P165L, I271N and C363Y adversely affected the trafficking
of WT endoglin by reducing its maturation and plasma membrane
localization. These results strongly suggest dominant negative effects
exerted by these ER-retained variants aggravating endoglin loss of
function in patients expressing them in the heterozygous state with the
WT allele. Moreover, this study may explain some of the variability
observed among HHT1 patients due to the additional loss of function
exerted by the dominant negative effects in addition to that due to
haploinsufficiency. These findings might also have implications for some
of the many conditions impacted by ERAD.
Microfluidics-A novel technique for high quality sperm selection for greater ART outcomes
Authors: Bhat Gh Rasool , Lone Farooz Ahmad
Published: July 2023

Microfluidics represent a quality sperm selection technique. Human
couples fail to conceive and this is so in a significant population of
animals worldwide. Male/sperm contributes a lot to infertility, so are
outcomes of assisted reproduction affected by sperm. Microfluidics,
deals with minute volumes of liquids run in small scale microchannel
networks in the form of laminar flow streamlines. Microfluidic sperm
selection designs have been developed in chip formats, mimicking in vivo
situations. Here sperms are selected and analyzed on the basis of
motility and sperm behavioral properties. Compared to conventional sperm
selection methods, this selection method enables to: produce high
quality motile sperm cells possessing non-damaged or least damaged DNA,
achieve greater success of insemination in bovines and achieve enhanced
pregnancy rates and live births in assisted reproduction-In Vitro
Fertilization (IVF) and Intra Cytoplasmic Sperm Injection (ICSI).
Besides, the concentration of sperm available to oocyte can be
controlled by regulating the flow rate in microfluidic chips. The
challenges in this technology are: commercialization of chips,
development of fully functional species-specific microfluidic tools,
limited number of studies available in literature and need of more
understanding in reproductive physiology across species for domestic
animals. In conclusion, microfluidics in assisted reproduction are great
advances having advantages for quality sperm selection. Future
directions to make this technology superior may need to modify chip
designs to formulate species specific low-cost chips for
commercialization. Comprehensive studies in animal species need to be
carried out for wider application of microfluidic sperm selection in
invitro procedures.
Education of experts in centers for social work in the Republic of Serbia in the domain of gender-based violence
Authors: Milanov Tamara , Cumura Ljiljana
Published: July 2023

Professionals (experts) employed in centers for social work have a crucial
role in preventing and responding to gender-based violence. The aim of the
research was to examine and present the current situation related to the
education of experts and opportunities for acquiring specialized knowledge
about gender-based violence. Data collection was carried out using a survey
technique (online questionnaire) and later processed through a descriptive
method, statistical inference and content analysis. Qualitative and
quantitative data were obtained from a sample of 74 respondents from 26
districts in the territory of the Republic of Serbia. According to the
results, 87.8% of the respondents believe that the knowledge they received
during the education process is insufficient for work in gender-based
violence. Out of the total number, 67.6% did not have courses/subjects
related to gender-based violence during their studies. At the same time,
more than half of the respondents did not attend officially accredited
training available in Serbia. The results indicate the need for improving
educational content in two important areas: 1) individual work with victims
and perpetrators of gender-based violence and 2) the structural nature of
gender-based violence and the possibilities of prevention.
The nature of female genital mutilation according to the Istanbul Convention and other international instruments
Authors: Markovic Ivana
Published: July 2023

The paper deals with the nature of female genital mutilation (FGM) as a
highly gendered, harmful practice, which has in the meantime been formalized
as a crime. Especially the Istanbul Convention is regarded as the driving
force behind this legal development. But beyond that, this Convention, as
well as the Convention of Belem do Para and the Maputo Protocol before that,
have defined and located the very nature of FGM within the violence against
women. By doing so, prior (false) beliefs and attempts to legitimize them
due to cultural, social or religious reasons have become obsolete. The aim
of this paper is to show the nature of FGM within the aforementioned
instruments.
Combating and preventing domestic violence in Poland: Why do we need the Istanbul Convention?
Authors: Skorulska Olga
Published: July 2023

The subject of the article is to present the regulations of the Polish legal
order aimed at combating and preventing domestic violence and juxtapose them
with the obligations under the provisions of the Istanbul Convention. The
article aims to answer the question of whether the Polish legal system makes
it possible to effectively combat and prevent domestic violence in
accordance with the announcements coming from the Polish political scene
regarding the denunciation of the Istanbul Convention. Although recent
amendments to the laws on combating and preventing domestic violence led to
more effective combat against it and improve the situation of victims, it is
also necessary to point out some deficiencies that have not yet been
addressed by the Polish legislator.
Usability Evaluation of the Top 10 Universities in Iraq Using Heuristic Methods
Authors: Abdulla Raza , Faraj Hiwa A. , Mohammed Kazhan O. , Younis Mahdi M.
Published: July 2023

A heuristic evaluation ‎ model is proposed for assessing the usability of the Top 10 Iraq university websites. ‎This model is based on 3 hierarchies of website usability criteria levels. The top hierarchy level consists of five website categories: design and layout, learnability, content, performance, and errors. In the middle hierarchy level 18 subcategories, and in the bottom hierarchy level 44 elements were described. The evaluation model utilized both automated tools and observation methods. To validate the results obtained by the proposed model, the selected universities were evaluated and scored according to the usability criteria of their websites. Besides the observation elements, the four automated tools (thinkwithgoogle, gtmetrix, tools. Pingdom, and webpagetest) were also used to assess the error and performance of the websites. The study showed that except for the University of Kufa and Baghdad University websites, the rest of the university websites failed to meet the applied website usability criteria levels of the proposed evaluation model.
Nano S_β-Connectedness in Nano Topological Spaces
Authors: Ahmed Nehmat K. , Pirbal Osama T.
Published: July 2023

The aim of this study is to introduce the notions of nano Sβ-connected, nano Sβ-hyperconnected and nano Sβ-ultraconnected by using all forms of nano Sβ-open sets in nano topological spaces. Then, we study their relationship and show that if a nano topological space is nSβ-connected, W is also nano connected space but not the converse. Also, we study each notion in terms of upper, lower, and boundary approximations.
Study the structural and mechanical properties of HAP-MgO NPs-PMMA nano-composite
Authors: Sadeq Jawaher Abdulelah , Hussain Randa Kamel , Abdul Majeed Aseel Mustafa
Published: July 2023

Polymer composite of heat cure acrylic (PMMA) matrix reinforced with different weight of nanoparticles Hydroxyapatite and Magnesium Oxide (1, 5 and 10% wt.) were prepared by hand molding technique. The Magnesium oxide nanoparticles were synthesized by Simple Chemical Method (Co-precipitation). The structure and morphology properties of MgO examined by X-ray diffraction (XRD), Field Emission Scanning electron microscopy (FESEM) and EDX. Lattice constant is a= 4.19
Determination the Optimum Conditions for β-glucan Production Extracted from Saccharomyces cerevisiae
Authors: Khadam Alyaa Abdulhussein , Salman Jehan Abdul Sattar , Hijri Mokhtar
Published: July 2023

Β-glucan is a natural polysaccharide composed of a group of glucose monomers linked by beta glycoside bonds that yeasts can be synthesized. The effect of different temperatures, inoculum size, glucose concentration, yeast extract concentration, pH, and culture media on the β-glucan production from saccharomyces cerevisiae was studied. In addition, the dry weight of biomass containing β-glucan was measured. The results showed that the optimum conditions for β-glucan production were when the cells were grown at 30 ºc for 48 hours and pH = 7 with 10 % inoculum size, 2% glucose, and 0.1% yeast extract. Furthermore, the best culture medium for β-glucan production was yeast extract-glucose medium with a dry weight of glucan 2.5mg/5ml. In addition, this study aimed to determine the best method for β-glucan extraction with acceptable purity and concentration. Β-glucan was extracted using two methods autolysis and alkali-acids extraction. The dried and weighed crude β-glucan was 6 gm/l, and 8 gm/l for autolysis of yeast cells, and alkali-acids extraction, respectively. The analysis of glucan by FT-IR and HPLC showed that the method of extraction by autolysis of yeast cells was successful to obtain β-glucan without the presence of the α-glucan with a concentration of β-glucan 10.8mg/gm, while in the extraction by alkali-acid were obtained mixtures of α-glucan and β-glucan with the concentration of β-glucan 7.4 mg/gm. The current study revealed that the optimum conditions of β-glucan production and the best culture medium for β-glucan production was yeast extract-glucose medium and the best method for β-glucan extraction was autolysis extraction.
Natural Ingredients in the Jimen Basin Using Remote Sensing Technology
Authors: Khalel Mohammed Hazim , Hamza Ali Fuad , Khaled Firas
Published: July 2023

The scarcity of water resources constitutes a real problem facing man on an ongoing basis, especially with the exacerbation of environmental degradation and drought that affected large parts of the globe. With the increase in the number of the earth's population, the world is in need of more water sources for various activities. The study of the importance of water harvesting in its economic and environmental advantages lies in the impact on increasing and improving the productivity of agricultural crops by providing additional water at a low cost using supplementary irrigation. Remote sensing and applications of informatics systems are used to detect the best sites for the application of rainstorm water collection methods. This study aims to produce a map of the optimal sites for water harvesting methods to benefit from the water at the site of its fall without waiting for it to reach the downstream in Jimen Basin. This site is characterized by the presence of geological formations that have an important role in the application of water harvesting such as solid formations that allow the construction of dams within the basin. The study analyzed a lot of data on air temperature, solar radiation, relative humidity, evaporation, and rainfall amount. The geological formations, natural plants, and types of soil were also studied. It was found that Jimen Basin is very suitable to be used as a water harvesting basin to develop the region around the basin which is semi-arid. In conclusion, the proposed lake can help provide the possibility of establishing a residential city and also be a promising tourist site.
Synthesis and Characterization of PMMA/HAP/MgO Nanocomposite as an Antibacterial Activity for Dental Applications
Authors: Sadeq Jawaher Abdulelah , Majeed Aseel Mustafa Abdul , Hussain Randa Kamel , Bamsaoud Salim F.
Published: July 2023

The current work focuses on the preparation of magnesium oxide nanoparticles using aqueous magnesium chloride salts and sodium hydroxide powder by a simple chemical precipitation method and at an annealing temperature of 700 °C for 6 hours. The structural and morphological properties of the magnesium oxide nanoparticles were investigated using X-ray diffraction (XRD). Polycrystalline cube and using the Scherer equation showed a crystalline size of 17.23 nm. EDS analyzes showed high purity. Scanning electron microscopy (FESEM) showed the spherical shape of the magnesium oxide particles. With particle size within the range (65-185) nm. While a (PMMA)-HAP nanocomposite was synthesized. -MgO) for use in dental applications such as fillings and dentures. A nanocomposite (PMMA-HAP-MgO) was manufactured by manual molding method by strengthening the poly methyl methacrylate polymer with certain weight ratios(1%,5%,and 10%) from a mixture of nano powder where the added ratios were  (99%PMMA-1%HAP,95%PMMA-7.4%HAP-0.3%MgO,and 90%PMMA-9.4%HAP-0.3%MgO). The topographical properties (surface roughness) of the nanocomposite samples were studied by testing them with an atomic force microscope. The results showed an increase in the value of pure PMMA, where the use of nanoparticle filler by 5% (4.7% HAP -0.3% MgO) affected both the roughness and the root mean square ratio of the distribution of nanoparticles on the surface of the composite and the shape of the particles led to a roughness more than the polymer pure. The antibacterial activity of the polymeric overlay was examined on the bacteria that cause dental caries for (Streptococcus mutans), where the zone of inhibition were (1 mm, 2 mm, 5 mm) for the nanocomposite and no activity for pure PMMA.
Enhancement of ChatGPT using API Wrappers Techniques
Authors: Younis Muhanad T. , Hussien Nadia Mahmood , Mohialden Yasmin Makki , Raisian Komeil , Singh Prabhishek , Joshi Kapil
Published: July 2023

This study looks at how API (Application Programming Interface) wrapper technology can make it easier to use complex functions by putting together a lot of API calls. These packages have non-real-time interfaces that are hard to use. ChatGPT is a chatbot-specific GPT-3 language paradigm. It lets developers create chatbots that respond intelligently to natural language user input, creating a more engaging user experience. This article shows that ChatGPT, Python, and API wrapper technology may be used to develop a smart chatbot. We show how to use the OpenAI API library to add ChatGPT to Python programs. This makes it easier for developers to make chatbots that sound and act more like real people when they talk. Our contribution to this field is showing that it is possible to make smart chatbots with ChatGPT and API wrapper technology. To reach this goal, we use a system that combines the OpenAI API with ChatGPT and Python. This gives us valuable information about how to make smart chatbots. The efficiency of the system has been tested many times while applying it to different environments, and the results are satisfactory.
Question Speech Act Produced by the Junior High School Students
Authors: Hendrayani Kadek Nila , Tantra Dewa Komang , Ramendra Dewa Putu
Published: July 2023

A question speech act is a communicative act that shows the intended language function, including questions, requests, apologies, suggestions, commands, and offers. This study aimed analyze the questions speech act types, question speech act social function, question speech act linguistics structure3 and questions speech act language elements produced by students in junior high school level. The study used descriptive qualitative. The subject of this study was seventh-grade students in junior high school. The data were collected through the elicitation technique. The analysis of this study included data collection, data reduction, data display, and conclusion drawing. The analysis result showed that from 960 questions, the students more frequently write two types of questions: yes/no questions and wh questions, rather than rhetorical questions and tag questions. The social functions used were directive functions speech act includes asking and requesting. The structure of yes/no questions was used verb in the beginning sentence then followed by the subject. Meanwhile, the structure of wh question was used wh then followed by an auxiliary verb, subject, and main verb. The result showed that non-effective questions were higher than effective questions, there were grammatical errors found that make the questions not effective. The language element of the questions speech acts based on the semantics situation types. The result showed that states is higher than activity, accomplishment, semelfactive and achievement.
The 2D Educational Game Prevention of Covid-19 in Indonesia
Authors: Sudarmilah Endah , Mulyana Afrizal Meka
Published: July 2023

The emergence of a corona virus called Covid-19, has caused a pandemic throughout the world, especially Indonesia. Many people do not understand about this virus. The game, which was developed with 2D-based Construct 3, is expected to attract more users’ attention to learn about Covid-19, such as Symptoms, History, Health Protocols, and Vaccines. Then, along with the development of increasingly advanced technology, it will facilitate learning and socialization, namely with this Quiz Game. This study intends to create a Covid-19 quiz educational game developed with quizzes of various levels for users to achieve, with research subjects people in general. This game uses the SDLC (System Development Life Cycle) method with the waterfall method. SDLC waterfall is one of the many system development methods that is quite popular and is often used by system developers, web-based applications, information systems, but not only that SDLC waterfall can also be applied in various other software, one of which is in the development game applications, especially educational games. The test results will use blackbox in the quiz educational game, and run without any errors or defects. The results of the validity and reliability test of the 70 people’s questionnaire are respectively valid and consistent/reliable. It can be concluded that the development of this game can help to educate the Indonesian people regarding Covid-19.