bluuebunny/crossref_metadata_2025 huggingface dataset:
MGB Block ARMS Real-Time PCR for Diagnosis of CYP2C19 Mutation in a Chinese Population
Authors: Jiang Xi-Wen , Liu Yue , Huang Tao-Sheng , Zhu Xiao-Ya
Published: January 2019

Background:

CYP2C19 is an important genetic factor modulating clopidogrel dose requirement.

Objective:

Therefore, a simple and economic genotyping method for predicting the clopidogrel dose of patients would be useful in clinical applications.

Methods:

In this study, the MGB blocker ARMS real-time PCR contained two forward primers, two MGB blockers and a common reverse primer have been used for CYP2C19*2, *3 and *17 substitutions.

Results:

Results showed that heterozygotes and homozygotes of CYP2C19*2, *3 and *17 could be distinguished by the MGB blocker ARMS real-time PCR successfully. In the Chinese population, patients with allele frequencies of CYP2C19*2, *3, and *17 are 18.43%, 3.03% and 0.76%, respectively.

Conclusion:

This study indicates that the MGB blocker ARMS real-time PCR will be a simple, economical method for the rapid detection of SNPs in CYP2C19.
New Frontiers in the Therapeutic Approach of Patients with Cardiovascular and Endocrine Diseases
Authors: Grande Dario , Terlizzese Paola , Gioia Margherita I. , Parisi Giuseppe , Giagulli Vito A. , Triggiani Vincenzo , Iacoviello Massimo
Published: January 2019

Background and Objective:

Cardiovascular disease is the most important cause of morbidity
and mortality worldwide, with a significant economic burden, which is expected to increase in the next
years. Alongside the management of cardiac manifestations and major risk factors for atherosclerosis,
great attention has been paid to the role of comorbidities in initiating and worsening cardiac conditions.

Discussion:

The cardiovascular impact of a broad spectrum of endocrine disorders has been evaluated,
with particular regard to their effects on cardiac function and cardiovascular prognosis in affected patients.
Among the different endocrine conditions considered, the association between subclinical hypothyroidism
and cardiovascular events is still uncertain. A number of observational studies have linked
subclinical hypothyroidism (in particular severe elevation of TSH levels) with incident cardiovascular
disease and poor prognosis, however thyroid replacement therapy is still controversial, especially in the
elderly, due to the lack of evidence coming from randomized controlled trials. With regards to testosterone
deficiency, even though it has been associated with metabolic abnormalities and poor prognosis
in patients affected by cardiovascular diseases, the cardiac safety of replacement therapy has still to be
completely clarified. Similarly, growth hormone deficiency showed detrimental effects on cardiovascular
events and risk factors which seem to be reverted by replacement therapy, even if unequivocal
evidence from randomized clinical trials is still lacking Another relevant chapter in cardiovascular
disease management is about the cardiovascular outcomes of diabetes medical treatments. In recent
years, a growing interest has been developed around the cardiovascular safety of antidiabetic medications
which has led to a great number of publications addressing this issue for the different classes of
antidiabetic drugs. Interestingly, the recently approved classes, i.e. incretins and SGLT-2 inhibitors,
have additionally demonstrated a protective effect against major cardiovascular events, shedding new
light on the management of diabetes in patients affected by cardiovascular disease.

Conclusion:

Important controversies still exist regarding the cardiac implications of the therapies
adopted in endocrine diseases. Owing the large prevalence of these conditions, particularly in the cardiovascular
population, further research is awaited in order to clarify the potential advantage and the
possible cardiac risk related to treatment of the endocrine comorbidities.
Kirschner Wire Migration into SpinaL Canal after Acromioclavicular Joint Fixation (Literature Review and Clinical Case)
Authors: Gulyaev D. A. , Godanyuk D. S. , Kaurova T. A. , Krasnoshlyk P. V. , Maikov S. V.
Published: January 2019

Fracture and migration of metal implants is a well-known issue which is especially relevant for actively loaded zones with a high amplitude of physiological movements. The authors analyzed 17 publications dedicated to Kirschner wire migration into the spinal canal after fixation of acromioclavicular joint (ACJ) injury. The present paper contains literature review and own clinical case of the authors. The authors generalize the conceptions of migration causes, surgical tactics and prevention recommendations. The key reason of fracture and migration of Kirschner wires during fixation of ACJ injury is the instability of implants, trans-articular wire insertion during fixation of reduced dislocation of acromial end of the clavicle, insufficient immobilization and untimely implants removal after removal of immobilization. Implants migration into the spinal canal is the indication for their surgical removal irrespective of clinical signs. In the majority of studied publications authors described posterior approach or lateral approach aligned with the migration direction. No grafting techniques for dura mater defects were present in the studied literature. The authors of the current paper justify a surgical procedure for removal of migrated implant using a combined posterior and lateral approach on the own clinical case. The choice of procedure algorithm results from the need for prophylaxis of secondary spinal cord lesion and liquorrhea during removal of migrated implants from spinal canal.
Social Connection and Online Engagement: Insights From Interviews With Users of a Mental Health Online Forum
Authors: Smith-Merry Jennifer , Goggin Gerard , Campbell Andrew , McKenzie Kirsty , Ridout Brad , Baylosis Cherry
Published: January 2019

Background

Over the past 2 decades, online forums for mental health support have emerged as an important tool for improving mental health and well-being. There has been important research that analyzes the content of forum posts, studies on how and why individuals engage with forums, and how extensively forums are used. However, we still lack insights into key questions on how they are experienced from the perspective of their users, especially those in rural and remote settings.

Objective

The aim of our study was to investigate the dynamics, benefits, and challenges of a generalized peer-to-peer mental health online forum from a user perspective; in particular, to better explore and understand user perspectives on connection, engagement, and support offered in such forums; information and advice they gained; and what issues they encountered. We studied experiences of the forums from the perspective of both people with lived experience of mental illness and people who care for people with mental illness.

Methods

To understand the experience of forum users, we devised a qualitative study utilizing semistructured interviews with 17 participants (12 women and 5 men). Data were transcribed, and a thematic analysis was undertaken.

Results

The study identified 3 key themes: participants experienced considerable social and geographical isolation, which the forums helped to address; participants sought out the forums to find a social connection that was lacking in their everyday lives; and participants used the forums to both find and provide information and practical advice.

Conclusions

The study suggests that online peer support provides a critical, ongoing role in providing social connection for people with a lived experience of mental ill-health and their carers, especially for those living in rural and remote areas. Forums may offer a way for individuals to develop their own understanding of recovery through reflecting on the recovery experiences and peer support shown by others and individuals enacting peer support themselves. Key to the success of this online forum was the availability of appropriate moderation, professional support, and advice.
Strategi Self-Regulated Learning dalam Meningkatkan Prestasi Belajar Matematika pada Siswa SMP
Authors: Anas Prima Soraya , Alsa Asmadi
Published: January 2019

This research aims to determine the relationship between self-regulated learning and mathematics achievement in junior high school students. The dependent variable in this research is mathematics achievement which is measured using the mid-term examination. The independent variable is self-regulated learning measured using a scale of self-regulated learning developed based on Zimmerman’s theory (1989). Hypothesis was there is positive relationship between self-regulated learning and mathematics achievement. Subjects were 129 grade VIII students of SMP Negeri X in the year of 2016/2017. Data was analysed using Pearson’s product-moment correlation technique. Results showed that there is a significant positive relationship between self-regulated learning and mathematics achievement, r = 0.351 (p < 0.01). As a conclusion, the hypothesis was accepted.
“Living” Epics in Central Highland-Vietnam
Authors: Dung Nguyen Tien
Published: January 2019

This article is about h’mon, an epic genre of Bahnar ethnic in the Central Highlands of Vietnam. Typical of this epic type is H’mon Dam Giong (or The Dam Giong epics). The contents of this article include space and mode of performance of h’mon; characteristics of the “living epic” of h’mon (It is the ability to refresh the content of h’mon by adding new details); characteristics of the character system (including the central character and the re-appearing characters).
NANODISCS: A NEW EPOCH IN THE STUDY OF MEMBRANE PROTEINS AND AS AN EMERGING DRUG DELIVERY SYSTEM
Authors: K. Arya G. , Kumar Anjaly A. , Nair Archana J. , Raju Jeni , Nair Sreeja C
Published: January 2019

Nano discs recently evolved as a novel tool for studying the membrane associated proteins and serve as an effective drug delivery system. Nano discs constitute disc shaped nano particles and can be defined as a membrane system which is synthetic in nature and aids in the study of membrane proteins. It is mainly made of phospholipid bilayer and the water repelling edge is isolated by amphipathic proteins called membrane scaffolding proteins [MSP]. Micelles present in the nano disc mimics the property of the biological membrane proteins. It is a powerful technology that competently delivers the drug components in to the right cells in the right tissues. Membrane scaffold proteins are primarily expressed, purified and characterized and self-assembled to form Nano discs by the process of dialysis using biobeads. Nano discs are proven to be effective in the study of membrane proteins because they can fluidize and counterbalance and also help in reclusion, refinement, biophysical and biochemical studies of them. It also presents a more genuine environment than liposomes, bicelles, amphipols and detergent micelles. Major technological advantages of nano discs include the higher stability and carrier capacity and also the increased feasibility of incorporating both hydrophilic and hydrophobic substances of drug carrier. Thus nano discs serves as an excellent system in its ability to precisely control its composition and provide a nano scale membrane surface for investigating molecular recognition events. This article reviews the emphasis of nanodiscs in studying membrane proteins as well as its effectivity in transforming into a major drug delivery system. An overview of published literatures between 1996 and 2017 was conducted to write the review.
FORMULATION AND EVALUATION OF FLOATING IN SITU GEL OF CIPROFLOXACIN
Authors: Pashikanti Shailaja , B. Jyothsna
Published: January 2019

Objective: The objective of the study was to develop floating in situ gel formulations of Ciprofloxacin that has a narrow absorption window and mainly absorbed in the proximal areas of GIT. These formulations increases the targeted action on bacteria for a longer time that can be used in the treatment of Helicobacter pylori (H. pylori) infections and urinary tract infections.Methods: In situ gel formulations were prepared by varying concentrations of sodium alginate as in situ gel forming bio-degradable polymer and calcium carbonate as a cross-linking agent. The formulations were evaluated for Physical appearance, pH, in vitro drug release, viscosity, in vitro floating behaviour, in vitro gelling capacity and drug content. FTIR was conducted for Ciprofloxacin, excipients used and optimized formulation.Results: All the formulations showed an optimum viscosity that will allow ease of administration and swallowing. Floating lag time of all formulations was between 32-70 seconds and floated for>12 h. The in vitro gelling capacity increased with increasing the polymer and gelling agent concentrations. Increase in polymer concentration decreased the rate and extent of the drug release. Among all the formulations, F4 containing 4% w/v of sodium alginate and 4% w/v of calcium carbonate showed sustained in vitro drug release (95.6%) over an extended period of 12 h. FTIR studies revealed no interaction between drug and excipients used. Drug release from the formulations followed First order kinetics with Fickian diffusion.Conclusion: Ciprofloxacin was successfully formulated as a pH-triggered floating in situ gelling system using sodium alginate.
FORMULATION, STANDARDIZATION, AND EVALUATION OF POLYHERBAL DISPERSIBLE TABLET
Authors: Maurya Harikesh , Kumar Tirath
Published: January 2019

Objective: The study was designed as formulation, standardization, and evaluation of polyherbal dispersible tablet prepared for the management of kidney disorders. To overcome the problem of dyspepsia in geriatric patients by the use of polyherbal dispersible tablets.Methods: Dispersible tablets were prepared using aqueous root extract powder of the selected plant viz. A. officinalis, B. diffusa, C. papaya, C. fistula, C. intybus, F. hispida, F. indica, C. nurvala, S. virgaurea, and V. negundo with the help of superdisintegrant addition technique using crospovidone, sodium starch glycolate and croscarmellose sodium in different percentage. Evaluation assessments such as the substantial test, weight variation, hardness, friability, content uniformity, disintegration, in vitro dispersion, stability study and IR compatibility were carried out.Results: Micromeritics of extracts powder were determined for all formulation, which signifying good flow properties. The substantial examination was established, which comply with official requirements for uniformity test, and the drug content was close to 100% in all formulations. Disintegration time was observed for all formulation in which the polyherbal formulation-3 (PHF-3) showing 1.10±0.10 min; during in vitro dispersion time, all formulation showed appropriate dispersion in which the PHF-3 captivating 2.00±0.45 min only. The IR compatibility shows none chemical interaction between the extracts and excipients.Conclusion: The PHF-3 showed satisfactory disintegration and in vitro dispersion time due to crospovidone and reported as the best formulation. The stability study and IR compatibility validate the PHF may represent new easily swallow dispersible tablet that may enhance drug permeability and advance bioavailability for nephrotic patients.
GROWTH FACTOR LOADED FUNCTIONALIZED GOLD NANOPARTICLES AS POTENTIAL TARGETED TREATMENT FOR ACUTE RENAL FAILURE
Authors: Zayed Gamal M. , El-feky Gina S.
Published: January 2019

Objective: Gold nanoparticles (GNPs) have been synthesized and functionalized with chitosan alkanethiol polyethylene glycol as a renal targeting ligand (CS-PEG-AlkSH-GNPs) and finally loaded with insulin-like growth factor-I (IGF-I) for selectively and effectively treating acute renal failure.Methods: In this study, GNPs were prepared and characterized using transmission electron microscopy, photon correlation spectroscopy and inductively coupled plasma (ICP-OES). The surface of the GNPs was further decorated using synthesized CS-PEG-Alk-SH and IGF-I. IGF-I loaded CS-PEG-ALK-SH-GNP were characterized for their growth factor loading capacity, particle size, zeta potential and dispersion stability. In vitro release profile and bioactivity of IGF-I from IGF-I loaded CS-PEG-AlkSH-GNPs were assessed using cell culture technique. Biological distribution, pharmacokinetic investigation and toxicity study of IGF-I loaded CS-PEG-AlkSH-GNPs were carried out using experimental animals.Results: The size of GNPs was less than 50 nm with a surface charge of about-45 mV. Coating GNPs with CS-PEG-Alk-SH acquired the particles high in vitro stability in 5 M NaCl and bovine serum albumin (BSA). The assembly’s bioactivity was tested on cell culture and the released IGF-I was found to maintain bioactivity equivalent to its released percentage. When tested on mice, IGF-I loaded CS-PEG-ALK-SH-GNP reached a concentration of 60% in 6 h time in the kidneys with an elimination half-life higher than that of the control GNPs indicating efficient renal residence and targeting processes. The system was proved nontoxic.Conclusion: CS-PEG-AlkSH-GNPs could represent an efficient tool for the targeted delivery of growth factors and other biomolecules to the kidneys.
PHOTOCATALYTIC DEGRADATION OF PHARMACEUTICAL DRUG ZIDOVUDINE BY UNDOPED AND 5 % BARIUM DOPED ZINC OXIDE NANOPARTICLES DURING WATER TREATMENT: SYNTHESIS AND CHARACTERISATION
Authors: Bhamare Vijaykumar S. , Kulkarni Raviraj M.
Published: January 2019

Objective: To study the photocatalytic degradation of pharmaceutical drug zidovudine (ZDV) by synthesized undoped zinc oxide nanoparticles (ZONPs) and 5% (mole ratio) barium doped zinc oxide nanoparticles (BZONPs) during water treatment.Methods: Kinetics studies were carried out with the help of UV-Visible Spectrophotometer. High-Resolution Mass Spectrophotometry (HR-MS) was used to identify products. A photo-reactor with mercury lamp was used as an external source of light energy. Optical power meter was used for the measurement of light intensity. The particle size of the synthesized photocatalysts was identified with the help of siemens x-ray diffractometer (XRD). The surface topography of photocatalysts was done by scanning electron microscope (SEM). Transmission electron microscopy (TEM) was used for the studies of particle size and morphology.Results: Five degraded products of ZDV are identified by HR-MS. A suitable electron-hole pair mechanism is projected. XRD patterns show that the intensity of peak is slightly stronger in ZONPs. There is an increase in the rate of photocatalytic degradation of ZDV by adding different quantities of photocatalyst from 0.05 g l-1 to 0.1 g l-1. The kinetic data reveals that there is an initial increase in the values of rate constants with the increase in the concentration of ZDV. The kinetic data indicate that the values of rate constants are higher at pH = 9. There is an increase in the rate constant values with an increase in the light intensities of UV lamp.Conclusion: The rates of photocatalytic degradation of ZDV were found to be higher using 5 % (mole ratio) BZONPs as a photocatalyst.
Editorial
Authors: Ulloa Hung Jorge
Published: January 2019

No precisa de un resumen.
Reseña del Tercer Seminario “Arqueología, Antropología e Historia en el espacio del primer encuentro colonial en Las Américas” (15 noviembre de 2018)
Authors: Ulloa Hung Jorge , Valcárcel Rojas Roberto
Published: January 2019

No precisa de un resumen.
FORÇAS MATERNAS UTILIZADAS DURANTE A HOSPITALIZAÇÃO DO RECÉM-NASCIDO PREMATURO NA UNIDADE DE TERAPIA INTENSIVA NEONATAL
Authors: Carvalho da Silva Karolina , Brandão da Silva Bruna , Reis Almeida Cinthia , Marques dos Santos Luciano , Pereira da Costa Kerber Nalú
Published: January 2019

Planos e expectativas são criados em torno do nascimento, porém quando esse evento ocorre prematuramente e o recém-nascido é levado para uma Unidade de Terapia Intensiva Neonatal, a família, em especial as mães, precisa enfrentar seus medos e fortalecer-se para auxiliar o bebê. Esta pesquisa objetivou analisar as forças utilizadas por mães de recém-nascidos prematuros hospitalizados na Unidade de Terapia Intensiva Neonatal. Trata-se de um estudo multicêntrico do tipo descritivo e qualitativo, realizado com 13 mulheres que tiveram parto prematuro, cujos recém-nascidos foram hospitalizados nas Unidades de Terapia Intensiva Neonatal do Hospital Geral Clériston Andrade e do Hospital Inácia Pinto dos Santos, em Feira de Santana, Bahia. Os dados foram coletados entre maio de 2014 a dezembro de 2015, por meio de entrevista semiestruturada, e foram analisados pela Análise de Conteúdo. Os resultados indicaram que poder ter o contato e cuidar do recém-nascido durante cuidado intensivo modifica o sentimento materno de vulnerabilidade, deixou a mãe mais fortalecida para enfrentar a situação. Conclui-se que, torna-se necessário que os trabalhadores de saúde atuantes na Unidade de Terapia Intensiva Neonatal reconheçam as forças maternas, e da própria família, utilizando-as como recurso para o enfrentamento do processo de hospitalização do prematuro e das demandas decorrentes desse processo.

Palavras-chave: Enfermagem neonatal. Prematuro. Unidades de Terapia Intensiva Neonatal. Sentimentos. Relações mãe-filho.
Importancia de la jerarquía social sobre los comportamientos alimenticios y parasitarios de ovinos criados en dos sistemas pastoriles
Authors: Flota-Bañuelos Carolina , Rivera-Lorca Juan A. , Candelaria-Martinez Bernardino
Published: January 2019

Para determinar la relación entre el nivel jerárquico, preferencias por forraje y parasitismo de ovinos en dos sistemas de pastoreo (sistema silvopastoril: SSP y monocultivo de pasto estrella: PE), se utilizaron 22 ovinos Pelibuey mantenidos en pastoreo diurno, a los cuales se les aplicaron pruebas de jerarquía social para obtener el índice de dominancia, pruebas de selectividad de especies vegetales forrajeras (C. nlemfuensis, L. leucocephala, G. sepium, G. ulmifolia y H. rosa-sinensis), análisis parasitario de huevecillos por gramo de excremento y determinación de hematocrito. Se observó una jerarquía no lineal con dominancia lineal y bidireccional para los grupos, de h=0.75 en el SSP y h=0.5 en PE. Los ovinos más dominantes presentaron mayor cantidad de conductas agresivas en el SSP y PE (rs= 0.790909, P=0.05 y rs= 0.845455, P=0.05); y menor carga parasitaria (rs= -0.909091, P=0.05) en el SSP y PE (rs= -0.727273, P=0.05). Los ovinos del SSP tuvieron preferencia por C. nlemfuensis, pero los animales que consumieron más follaje de L. leucocephala presentaron mayor nivel de hematocrito (rs=0.694269, P=0.05). Se concluye que los ovinos con mayor índice de dominancia que pastorearon en el sistema silvopastoril y en potreros con pasto estrella, tuvieron menores cargas parasitarias, y que el pastoreo en sistemas silvopastoriles ofrece a los ovinos el consumo de follaje de especies arbóreas y arbustivas, que promueve la capacidad de resistir cargas parasitarias elevadas, y mantener niveles estables de hematocrito independientemente de su nivel jerárquico dentro del grupo.
Possibilities to Apply the Urban Acupuncture Concept in Kaunas: Social Aspect
Authors: Daugelaite Aurelija , Gražulevičiūte-Vileniške Indre , Landauskas Mantas
Published: January 2019

The concept of urban acupuncture, which has been gaining ground in recent decades, is based on the activation and revitalization of urban environments using small architectural or landscape architectural interventions in precise carefully selected locations of urban fabric. However, the rapid and unexpected design solutions of urban acupuncture, based on ecological design, nature dynamics, street art, material re-use, can cause different social and psychological reactions of urban population and these reactions may vary depending on cultural contexts. Consequently, in order to implement successful urban acupuncture projects in Lithuanian cities, it is very important to find out public opinion and priorities in the fields of public space management, aesthetics, and public art. The aim of the research was to analyze the opinion of Kaunas city residents regarding these issues. For this purpose, a sociological questionnaire survey was used. The questionnaire containing 20 questions was designed, with the aim to find out the trends of use of public spaces in the city, the attitudes of residents towards street art and other small-scale initiatives in public spaces implemented in the recent years, possibilities of creating landscape architecture based on ecological ideas in urban environment, the attitude of inhabitants towards
community spaces and community space design in the city, etc. 100 residents of Kaunas participated in this online administered survey. The survey has demonstrated general positive attitude towards contemporary design trends of public spaces and public art; however, the surveyed population expressed preferences towards fully equipped public spaces offering possibilities for a wide range of activities.
Re-pedestrianising open spaces through optimising mobility in urban landscape: great importance of the small detail
Authors: Stauskis Gintaras
Published: January 2019

Many big, average and even small towns have been dramatically car-invaded through the past twenty years in Eastern Europe. That resulted in fragmented open spaces and endangered mobility through the streets and blocks of the city. The paper addresses the issue of comfortable access to urban open space by bringing the multidimensional approach that includes aesthetical, infrastructural and social tools and applications.
On the example of Joniškis town in Lithuania, the paper presents a solution toolkit for assessing the existing mobility situation, developing a re-pedestrianising action plan and programming the impact of the applied measures. The results of the multidimensional approach show that by giving priority for pedestrians against cars in urban open spaces and drive-ins cities can achieve multiple environmental and social-economic benefits. Open spaces become safer, more attractive and pleasing and more people visit them. The proposed model serves as a continuous professional development topic for landscape architects researching, teaching and designing in the private, public and non-governmental sectors.
The age of aesthetic perception of the environment - concept in architecture and historical data
Authors: Staniunas Eugenijus
Published: January 2019

The object of the research whose findings are presented in the article is on the contact line between two life “elements” – the popular contemporary architectural culture and data of contemporary historical knowledge. In the analysis, it is attempted to disclose how the notion “Aesthetics” is viewed from both sides of that line, seeking to ascertain whether contemporary architectural society sees the duration of an aesthetic attitude of the human being towards its environment in the same way how this make history data.
Aerosol loading and its effect on respiratory dysfunction disorder over Dapaong-Togo
Authors: Emetere Moses , Adeyemi Gbadegesin , Okoro Emmanuel , Sanni Samuel
Published: January 2019

It has been reported that respiratory dysfunction is responsible for 20% of deaths in Togo. There is need to know (in numerical value) the current state and future prediction of aerosol loading over the research site. The research is based on remote sensing techniques and proven mathematical models. Fifteen years primary (aerosol optical depth) dataset was obtained from the Multi-angle Imaging Spectro-Radiometer (MISR). The secondary datasets (aerosol loading, particles sizes, Angstrom exponent and the statistics of the primary dataset) was generated from the primary data. The average deposition efficiency of aerosols (into the human lungs) in the region is about 0.955. This research provides vital data for health referencing and on-ground investigation over Dapaong-Togo.
Ceramiczne odpady budowlane powstające w procesie rewitalizacji miasta – badanie możliwości ich wykorzystania jako substytutu cementu do betonów i zapraw
Authors: Zegardło Bartosz , Andrzejuk Wojciech , Drzymała Tomasz , Jaworska Beata , Nitychoruk Jerzy , Tokarski Daniel
Published: January 2019

The article indicates the issue of revitalization of urban areas on the example of the former provincial city. Particular attention was paid to threats to the natural environment caused by difficulties in managing construction waste arising during this process. During the research work on waste demolition material from repairs and reconstruction of buildings, ceramic construction waste was selected. These materials were crushed and dust was generated from them. The purpose of the work was to study the activity indicator, i.e. the research that is carried out for dusts obtained, e.g. in metallurgical processes. The parameter described was a determinant of the possibility of using dust as a recyclable cement substitute in concretes and mortars. The research material was ceramic waste. The waste was picked up from the landfill and sorted. Wastes of red ceramics were isolated in the form of damaged bricks, hollow bricks and roof tiles. Dust was produced from such prepared waste. The research methodology was carried out in accordance with the standard PN-EN 450-1:2012. The activity index of crushed ceramic dust after 28 days was 60.9%, after 90 days 72%. Given the slight change in the strength parameters of mortars and special considerations of the necessity of waste utilization, the described ceramic dust recycling is considered as a solution possible to implement in the production of mortars and non-structural concretes. Introduction of the results of these works to market activities may contribute to the reduction of waste deposited on landfills.
Reducing musculoskeletal disorder (MSD) risk of wiring harness workstation using workplace ergonomic risk assessment (WERA) method
Authors: Sugiono Sugiono , Budiprasetya Andhika , Efranto Remba
Published: January 2019

Bureau of Labor Statistics in Indonesia notes that musculoskeletal disorder (MSD) is the main category of injury causes in workplaces leading to 30% compensation costs. The purpose of this paper was to know the risk of work position of wire harness companies using workplace ergonomic risk assessment (WERA) for basic workstation improvements. The first step of this research was studying the literature of MSD, work posture, work position, and WERA. It subsequently proceeded with the identification and assessment process using WERA on each type of wiring harness activity. From the research results, it was obtained three jobs indicated causing muscle injury and soreness namely torque job, grommet job, and offline job. Moreover, the problem was supported by complaints from most workers known by using a discomfort survey. Based on the problem, this research was conducted to find out the action levels with WERA method and give improvement recommendation to overcome the problem of musculoskeletal disorders. The results of WERA showed that torque, grommet, and offl ine jobs needed further investigation and improvement with the scores of 31.23, 28.87, and 30.9. Recommendations were then given in the form of personal protective equipment (PPE) to reduce the risk factor scores on contract stress, to provide a new workstation design of torque job, and to add aids for solving other pain problems.
Kablosuz Algılayıcı Ağlarda Küme Başı Kapsama Alanının Farklı Ağ Boyutları ve Düğüm Sayıları Altında Ağ Yaşam Süresine Etkisi
Authors: ABASIKELEŞ-TURGUT İpek
Published: January 2019

Kablosuz
Algılayıcı Ağlarda (KAA) kaynakların kısıtlı olmasından dolayı enerjinin
verimli bir şekilde kullanılması problemi, kümeleme tabanlı mimarilerin bu
ağlarda yaygın olarak kullanılmasını sağlamıştır. Literatürde bu alanda yapılan
çalışmalar; küme başı seçiminde farklı parametreler kullanma, zamana dayalı
küme başı seçimi veya yapay zekâ algoritmalarıyla küme oluşumu gibi farklı
yöntemlerle enerjinin ağda verimli bir şekilde kullanılmasını amaçlamaktadır.
Oluşturulan kümelerin kapsama alanı bazı çalışmalarda tüm ağı kapsayabilecek
genişlikte seçilirken, diğerlerinde sınırlandırılmıştır. Bu çalışmada küme başı
kapsama alanı parametresinin ağ yaşam süresine olan etkisi ayrıntılı
benzetimlerle incelenmiştir. Farklı düğüm sayıları, farklı kapsama alanları ve
farklı ağ genişlikleri kullanılarak ilk, orta ve son düğüm ölümleriyle dışarıda
kalan düğüm sayıları raporlanmıştır. Elde edilen sonuçlara göre küme başı
kapsama alanının artması ilk düğüm ölümlerini gecikirken, orta ve son düğüm
ölümlerinin daha erken yaşanmasına neden olmaktadır. Ağ alanının artması ise
tüm düğüm ölümlerini daha erken bir döngüye çekerken en yüksek oranda etkiyi
ilk düğüm ölümlerinde, en az etkiyi ise son düğüm ölümlerinde sergilemektedir.
Düğüm sayısı arttıkça ilk düğüm ölümleri daha erken bir döngüye çekilirken,
orta ve son düğüm ölümlerinde gecikmeler elde edilmektedir. Elde edilen sonuçların
ışığında bu çalışmanın, gelecekte hem gerçek zamanlı hem de benzetim ortamında
tasarlanacak olan kümeleme tabanlı mimarilerde küme kapsama alanının tasarım
tercihlerine uygun olarak seçilmesine yardımcı olacağı düşünülmektedir.
Plastik Parçalarda Bir Esneyerek Kilitlenen Bağlantı Modelinin Modal Analizi
Authors: ERDEMİR Fulya , OZKAN Murat Tolga
Published: January 2019

Karmaşık
geometriye sahip enjeksiyon kalıplı plastik parça montajında, kimyasal
yapıştırıcı ve vidalama yerine esneyerek kilitlenen bağlantılar (snap-fits)
tercih edilmektedir. Bu bağlantıların kullanımı ara yüzey ve ilgili eşleşme
kuvvetinin doğru hesaplanmasına dayanmaktadır. Bu çalışma da, kiriş ya da
ayaklı diye tarif edilen ayakucunda kilitleme detayı bulunan bir bağlantı
elemanının Polilaktik Asit (PLA), Akrilonitril Bütadien Stiren (ABS) ve Polietilen
Terefitalat Glikol kopolimer (PET-G) malzemeleri kullanılarak elde edilen modeller
için Modal analiz işlemi gerçekleştirilmiştir. Modal analizden elde edilen
veriler kullanılarak harmonik cevap analizi yapılmıştır. Sonuçta elde edilen
veriler yorumlanmıştır.
Onnanoscale phenomena inthe electroacoustic sputtering process
Authors: Al-Tibbi W. H. , Minakov V. S.
Published: January 2019

Introduction. The effect of variable parameters of the electroacoustic sputtering (ELAS) process on the characteristics of the crystalline structure of hardening coatings is studied. The ELAS parameter values providing nanostructured cover coatings for machine parts and cutting tools are determined. Hardening through using such coatings allows achieving a significant (5-10 times) increase in the life of hardenable machine parts and various tools designed for mechanical processing. To obtain coatings with the desired properties of the surface layer, nanocrystalline materials should be selected. In this case, a certain content of the amorphous phase is permissible.

Materials and Methods. To carry out the X-ray structural analysis, the X-ray diffraction Russian-made device DRON-3M was used. The Scherrer-Wilson method was applied to determine the granularity of particle blocks from the value of the intrinsic broadening of the diffractogram peaks. The conclusions obtained in this paper are based on the method of separation of the affecting factor contributions into broadening the diffraction reflection peaks (the Warren-Averbach method).

Research Results. Depending on the process conditions and the technique for obtaining nanostructured materials, a nonuniquely interpretable change in the indices of the diffraction peaks broadening occurs, which is generally characteristic of nanocrystalline metals. One of the possible explanations for this phenomenon is the presence of a nanosized effect in the hardened layer. The occurrence of the nanocrystalline structure in the sputtered layer verifies the calculated values of the dimensions of the coherent scattering regions (CSR). The occurrence of affecting values of the misorientation angle of the crystal structure is verified by the CSR value for the investigated 110 and 220 reflexes, which is supported by a high percentage of the amorphous phase.

Discussion and Conclusions. The electroacoustic scattering method is promising for obtaining nanocrystalline structures in the surface and subsurface layers of the sprayed samples. The ELAS process variables variation leads to the parameter spread of the crystal lattice and coherent scattering areas. In this case, there is no definite trend. In the future it is expected to solve the given problem. First, experiments will be conducted to determine the optimal sputtering regimes that could stimulate the formation of nanocrystalline structures. Secondly, visual observation and evaluation of the sprayed layer structure using electron microscopy is planned.
Effect of design and kinematic parameters on energy requirement in inclined screw mixer
Authors: Khlystunov V. F. , Braginets S. V. , Alferov A. S. , Chernutskiy M. V.
Published: January 2019

Introduction. Rational parameters and modes of an inclined batch screw mixer are validated to achieve the lowest energyintensive feed mixing under observance of the zootechnical requirements for the feed quality on uneven mixing. The establishment of functional dependences between parameters and modes enables to design power-efficient equipment for the on-farm feed production.

Materials and Methods. Experimental studies of the feed mixing were implemented on an inclined screw batch feed mixer. The experimental design included variation of four independent factors: mixer shaft speed, filling ratio of the mixing chamber, mixing time, and mixing chamber angle. Mixing irregularity and energy intensity of the process were taken as optimization criteria characterizing the mixing efficiency.

Research Results.The optimization criteria versus the variability level factor, which are two-dimensional sections of the second-order response surfaces, are plotted. The rational values at mixing irregularity of less than 5% were as follows: mixer shaft speed was 27.5-36.5 min-1 , filling ratio of the mixing chamber was 0.43–0.51, mixing time was 3.0–4.2 min, mixing chamber angle was 22°–25°. At such parameter values, the mixing irregularity will be minimal, and it will be 4.10– 4.18%, and the process intensity is from 2.08 to 2.16 kW • h/t.

Discussion and Conclusions. The dependences obtained as a result of the experimental studies allowed establishing the domain of rational design parameters and modes of an inclined batch screw mixer. The results obtained can be used in further studies under the development of initial requirements for the creation of new technical means with a gravitation effect of intensive mixing.
Data measurement system for non-destructive quality testing of hard alloys
Authors: Tsybrii I. K. , Vyalikov I. L. , Ignatenko V. I.
Published: January 2019

Introduction. It is known that the quality of products from sintered hardmetals, if the fabrication technique is not violated, is determined by the phase composition and an average grain size of the carbide phase. However, hard alloys have a disadvantage inherent in all products of powder metallurgy - the inhomogeneity of the structure and the corresponding variation of properties. Traditional methods of monitoring the structure and phase composition according to the results of selective destructive tests prevent from receiving quality data under the production conditions and do not guarantee the identity of the properties of all batch products under study. The major method of non-destructive quality control of hard alloys is coercimetry, but domestic coercimeters are currently not produced. In this regard, the work objective is to create a domestic data measurement system for non-destructive quality testing of hard alloys and an assessment of the reliability of the results obtained with its help.  Materials and Methods. Cylindrical and spherangular rods with the diameter of 4 to 10 mm, made of alloys of VK8 and VK10HOM grades, were used in the work. The method of comparison with a certified product was used to determine the coercitive force in the data measuring system. Research Results. The coercive force of two batches of products from hard alloys of VK10HOM and VK8 grades was measured using the developed data measuring system and KOERZIMAT 1.097 HcJ coersimeter. Discussion and Conclusions. The experimental studies show that the values of the coercitive force of the samples obtained on different equipment have approximately the same level. 

The inhomogeneity of the structure characteristic of sintered hardmetals being a fabrication technique effect is confirmed. Providing that the relative error of measuring the coercitive force for each sample should be within ± 6%, the results obtained can be considered satisfactory. It is shown that the measurement algorithm proposed and implemented in the data measurement system through comparing the characteristics of the tested and certified samples with the known coercitive force, allows the manufacturer of hard alloy products to expand the sample of inspected products up to 100%, and to significantly reduce the costs for non-destructive testing of products.
Stationary model of salt ion transfer in two-dimensional electrodialysis desalting channel in galvanostatic mode
Authors: Uzdenova A. M. , Urtenov M. Kh.
Published: January 2019

Introduction. The theoretical description of the ion transport in membrane systems in the galvanostatic mode is presented. A desalting channel of the electrodialysis apparatus is considered as a membrane system. The work objectives are the development and verification of a two-dimensional mathematical model of the stationary transport of salt ions in the desalting channel of the electrodialysis apparatus for the galvanostatic mode.

Materials and Methods. A new model of ion transfer is proposed. It is based on the Nernst –Planck – Poisson equations for the electric potential and on the equation for the electric current stream function. A numerical solution to the boundary value model problem by the finite element method is obtained using the Comsol Multiphysics software package.

Research Results. The developed mathematical model enables to describe the stationary transfer of binary salt ions in the desalting channel of the electrodialysis apparatus. Herewith, the violation of the solution electroneutrality and the formation of the dilated domain of space charge at overlimiting currents in the galvanostatic mode are considered. A good agreement between the physicochemical characteristics of the transfer calculated by the models for the galvanostatic and potentiostatic modes implies adequacy of the constructed model.

Discussion and Conclusions. The developed model can interpret the experimental study results of ion transfer in membrane systems if this process takes place in the galvanostatic mode. Some electrokinetic processes are associated with the appearance of a dilated domain of space charge at overlimiting currents. When describing the formation of this domain, it is possible to find out how the processes dependent on it affect the ion transfer in the galvanostatic mode.
Parallel construction of binary tree based on sorting
Authors: Romm Ya. E. , Chabanyuk D. A.
Published: January 2019

Introduction. Algorithms for the parallel binary tree construction are developed. The algorithms are based on sorting and described in a constructive form. For the Nelement set, the time complexity has T(R) = O(1) and T(R) = O(log2 N) estimates, where R = (N2-N)/2 is the number of processors. The tree is built with the uniqueness property. The algorithms are invariant with respect to the input sequence type. The work objective is to develop and study ways of accelerating the process of organizing and transforming the tree-like data structures on the basis of the stable maximum parallel sorting algorithms for their application to the basic operations of information retrieval on databases.

Materials and Methods. A one-to-one relation between the input element set and the binary tree built for it is established using a stable address sorting. The sorting provides maximum concurrency, and, in an operator form, establishes a one-to-one mapping of input and output indices. On this basis, methods for the mutual transformation of the binary data structures are being developed.

Research Results. An efficient parallel algorithm for constructing a binary tree based on the address sorting with time complexity of T(N2) = O(log2 N) is obtained. From the well-known analogues, the algorithm differs in structure and logarithmic estimation of time complexity, which makes it possible to achieve the acceleration of O(Nα), α≥1 order analogues. As an advanced version, an algorithm modification, which provides the maximum parallel construction of the binary tree based on a stable address sorting and a priori calculation of the stored subtree root indices is suggested. The algorithm differs in structure and estimation of T(1) = O(1) time complexity. A similar estimate is achieved in a sequential version of the modified algorithm, which allows obtaining the acceleration of known analogs O(Nα), α>1 order.

Discussion and Conclusions. The results obtained are focused on the creation of effective methods for the dynamic database processing. The proposed methods and algorithms can form an algorithmic basis for an advanced deterministic search on the relational databases and information systems.
KANDUNGAN NUTRISI SERAT BUAH KELAPA SAWIT YANG DIFERMENTASI DENGAN FESES KERBAU PADA LEVEL YANG BERBEDA
Authors: Juliantoni Jepri , Mucra Dewi Ananda , Febrina Dewi
Published: January 2019

This study was conducted from January to March 2013 in the Laboratory of Nutrition and Chemistry, Faculty of Agriculture and Animal Husbandry of the State Islamic University of Sultan Syarif Kasim Riau and analysis of the nutrient content in Ruminant Nutrition Laboratory of the Faculty of Animal Husbandry, Andalas University in Padang. This study aimed to determine the effect of buffalo feces with different levels of fermentation fruit oil palm fiber (SBKS) for 21 day against pH, fermentation quality, dry matter content, crude fiber, crude protein, ash and BETN. The method used in this study is completely randomized design with 4 treatments and 3 replications. The treatment given is the number of buffalo feces levels (0%, 10%, 20% and 30%). The results showed that the addition of up to 30% buffalo feces fermentation SBKS gave highly significant effect (P <0.0 l) on the pH, but not significant effect (P> 0.05) increase levels of dry matter, crude protein and BETN, and declining levels of crude fiber and crude fat levels.
ECRANISATION STUDY: FROM NOVEL TO FILM DILAN 1990
Authors: Widhayani Arrie , Suwandi Sarwiji , Winarni Retno
Published: January 2019

The purpose of this study was to describe the form of ecranitation of novels into films the Dilan 1990 by Pidi Baiq and Fajar Bustami. Ecranisation is a study in the form of transfer of vehicles or transformation from a work of art into film. The transformation in this study is different from the form of presentation. This research used qualitative using the method of content analysis. The analysis of the research was carried out in an ecranisation approach. Data were collected through library studies and sources of data from Dilan 1990 novels and films. The result of the study showed the realization of ecranisation novel and film in the 190 Dilan with new shortcomings additions and variation from the content of the story and the constituent elements of the story.Keyword: Ecranisation, Dilan 1990, Literature, film, novel  AbstrakTujuan penelitian ini adalah untuk mendeskripsikan wujud ekranisasi dalam novel ke film Dilan 1990 karya Pidi Paiq dan Fajar Bustami. Ekranisasi merupakan kajian yang berupa alih wahana atau transformasi dari sebuah karya seni ke dalam bentuk film. Transformasi dalam kajian ini berbeda bentuk penyajiannya. Penelitian yang digunakan adalah kualitatif dengan menggunakan metode analisis isi. Analisis penelitian dilakukan pendekatan ekranisasi. Data dikumpulkan melalui studi pustaka, dan sumber data dari novel dan film Dilan 1990. Hasil penelitian menunjukkan wujud ekranisasi novel ke film Dilan 1990 adanya penciutan, penambahan, dan variasi baru baik dari isi cerita maupun unsur pembentuk ceritanya.Kata kunci: Ekranisasi, Dilan 1990, Sastra, film, novel