bluuebunny/crossref_metadata_2025 huggingface dataset:
Immunglobulınler ve Myastenia Gravıs: Geleneksel Derleme
Authors: Kaya Hilal , Halıcı Zekai
Published: December 2024

Myasthenia Gravis is an autoimmune disease characterised by the development of antibodies against proteins in the neuromuscular junction, resulting in complaints such as fatigue and muscle weakness. Quality of life is adversely affected due to complaints such as droopy eyelids (ptosis), blurred or double vision, difficulty in speaking, difficulty in swallowing and breathing. It causes morbidity and mortality due to myasthenic crisis and subsequent complications. Intravenous immunoglobulin therapy, plasmapheresis, anticholinesterase drugs, immunosuppressant drugs or thymectomy surgery can be applied in the treatment of myasthenia gravis, which can lead to serious permanent damage and rarely fatal consequences. Treatment preference varies according to the course of the disease. In this review, pharmacokinetics, administration procedures, adverse events, patient variables and cost considerations of intravenous immunoglobulin (IVIg) in myasthenia gravis will be discussed.
Alaşehir St. Jean Ören Yerindeki Karamanlıca Yazıtlar
Authors: Türkoğlu Inci
Published: December 2024

Eski Çağda Philadelphia adıyla bilinen Manisa İli Alaşehir İlçesinde bulunan St. Jean Ören Yeri, Havari Yuhanna’ya ithaf edilmiş bir kiliseye ait kalıntıları barındırır. Bu alanda Alaşehir ve çevresinde ele geçen kimi arkeolojik malzemeler de saklanmakta ve teşhir edilmektedir. Ören yerinde yaptığımız düzenleme ve belgeleme çalışmaları sırasında tespit ettiğimiz Karamanlıca yazıtlar bu çalışmanın konusunu oluşturmaktadır. Kurtuluş Savaşı sonunda kenti yakarak kaçan bu Rumlar hakkında fazla bilgiye sahip değiliz. Söz konusu yazıtların çoğu mezar taşı olup Alaşehirli Rumlar üzerine ışık tutmaktadır.
La oportunidad de la contratación conjunta esporádica en la Administración local: Cuando la unión hace la fuerza
Authors: Lomba Piquer María del Mar
Published: December 2024

Pese al elevado porcentaje que representa la contratación menor respecto del total de la actividad contractual que desarrollan las entidades locales y al indiscutible menoscabo que supone en la aplicación de algunos de los principios más importantes de la contratación pública, la contratación conjunta esporádica, en sus distintas formas, constituye en la práctica una opción poco explorada por las entidades que conforman el sector público local español. En tal particular contexto, el presente trabajo aborda esta figura a partir de la normativa vigente, analizando las singularidades que la caracterizan a través de las dos fases secuenciales en que su tramitación consiste, la primera, colaborativa, y la segunda, propiamente contractual, en un intento de ofrecer respuestas a algunas cuestiones clave no resueltas con claridad por la regulación aplicable.
ЖИЗНЕННЫЙ ПУТЬ ПЕРВОГО ПРЕДСЕДАТЕЛЯ ГЛАВНОГО СУДА БМАССР ГЕОРГИЯ ГЕОРГИЕВИЧА ДАНЧИНОВА
Authors:   Бурятский государственный университет имени Доржи Банзарова, Я. Р. Казанцев
Published: December 2024

В статье идет речь о жизненном пути известного революционера, одного из первых коммунистов-бурят, соратника М. М. Сахьяновой и М. И. Амагаева Г. Г. Данчинова. Приводятся сведения о детстве Данчинова, его семье, его родственных связях с М. Н. Хангаловым. Используются его воспоминания о работе в Монголии вместе с Сухэ-Батором, а также воспоминание о нем И. В. Ченкирова. Описываются его жизнь и трудовой путь в целом. Автор приходит к выводу, что биография Георгия Георгиевича Данчинова нуждается в дальнейшем исследовании. Наиболее полно отражена его революционная деятельность в отличие от других отрезков его жизненного пути, в том числе и вклада в национально-государственное строительство в БМАССР и все еще ожидает исследователей его биографии.
АРХЕОЛОГИЧЕСКИЕ ИССЛЕДОВАНИЯ В БУРЯТИИ (ВТОРАЯ ПОЛОВИНА XIX — НАЧАЛО XX в.): ИСТОРИОГРАФИЧЕСКИЙ СЮЖЕТ
Authors:   Институт монголоведения, буддологии и тибетологии СО РАН, Б. Л. Бальжанов
Published: December 2024

В статье рассматривается отечественная историография археологических исследований в Бурятии, охватывающая хронологический промежуток со второй половины XIX в. до начала XX в. Следует сразу отметить, что изыскания Троицкосавско-Кяхтинского отдела РГО в данной статье не рассматриваются, так как, на наш взгляд, его работы заслуживают отдельной статьи.
В данной публикации анализируются различные концепции ученых, исследовавших археологические культуры, территориально распространенные в современных границах Республики Бурятия. Очевидно, некоторые теории не выдержали проверку временем, что нисколько не умаляет заслуг наших предшественников, которые были ограничены научно-методологическим прогрессом своего времени, но именно их научный пыл поспособствовал в дальнейшем комплексному изучению памятников археологического наследия Бурятии. Настоящим трудом мы отдаем дань уважения первопроходцам археологических изысканий в Бурятии.
Voltage Controlled Oscillator Realisation with Temperature and Source Independent Circuits
Authors: Gür Müslüm , Babacan Yunus
Published: December 2024

In this article, a square wave was generated with a voltage-controlled oscillator circuit (VCO) using a bandgap reference voltage circuit and a low drop-out (LDO) circuit. The band gap reference circuit can generate a constant 500mV voltage between -40⁰C and +125⁰C. The LDO circuit is driven by a bandgap reference voltage circuit and exhibits a stable output even at different voltage levels. The last circuit, VCO, is driven by the LDO circuit. It can generate square waves between 1200MHz and 1600MHz at the output. Simulations using 130nm TSMC technology parameters have been successfully achieved.
Investigation of Influencing Factors on Power Generation Performance in Reverse Electrodialysis
Authors: Cihanoğlu Aydın
Published: December 2024

The importance of meeting energy demands from renewable sources is growing daily. Reverse electrodialysis (RED) is a membrane-based technology that produces energy using electrolyte solutions with different salinities. This study has generated energy from the RED system using the commercial Fujifilm Type II ion exchange membranes (IEMs). Many parameters affect the power generation performance of the RED system. This study systematically investigated the parameters, the presence of divalent ions and organic molecules, the electrolyte solution concentration, and the flow velocity. The flow velocity results indicated that energy efficiency increased with increasing flow velocity of the electrolyte solutions. The presence of divalent ions created uphill transport. The results showed that increasing the mole ratio of divalent ions in the feed electrolyte solutions dramatically decreased the RED system performance due to increasing resistances. The organic fouling test of the anion exchange membranes (AEMs) was carried out using a real humic and fulvic acid mixture under static conditions. The results indicated that fouling layers formed in the AEMs structure, and these layers decreased by 30% of RED performance. Lastly, the RED system's long-term performance was tested for 4 hours at a constant current density of 8 A/m2 before and after AEM fouling experiments. The results revealed the fouling layers severely reduced the power generation performance of the RED system.
A Mobile Secure Content Development Application for Children in the Software Development Life Cycle Framework
Authors: Karabaş İsakhan , Aslay Fulya , Öksüz Elif
Published: December 2024

This study deals with the software development process of a mobile application that will support children's learning, development and entertainment processes while ensuring their safety in the online environment. The project was carried out within the framework of the Software Development Life Cycle (SDLC) and adopted a systematic approach including requirements analysis, design, development, testing and maintenance phases. The application aims to provide appropriate content for children by minimizing digital security risks and to enable parents to safely control their children's internet use. With the Extreme Programming (XP) methodology, a continuous improvement process based on user feedback was implemented and security and performance tests were successfully completed. The article shows that not only coding but also effective management of the whole process in software development projects contributes to project success. The study is expected to contribute to the literature on children's digital safety and provide a basis for future research in this field.
Study on the efficiency of locking plate surgery with that of inter locking nail treatment in management of proximal humerus fracture in P. T. Birta City Hospital and Research Center
Authors: Belbase Rupesh J. , Shah Pradip , Limbu Kumud K. , Poudel Alson , Basnet Anil , Buohathoki Romi , Nepal Dikshya
Published: December 2024

Background: Proximal humeral fractures (PHFs) commonly exhibit a bimodal distribution based on trauma energy levels, affecting mainly those over 65 through low-energy falls, often indicating osteoporosis. Treatment approaches for displaced PHFs vary, with locking plates offering high stability but posing risks to blood supply and nerves. The efficacy of surgical versus conservative treatments remains debated, especially for complex fractures, with studies linking surgical options like intramedullary nailing and locking plates to mixed outcomes, including possible shoulder limitations. Aims and objectives were to evaluate the efficiency of locking plate surgery with that of interlocking nail in treatment in management of PHF.
Methods: A prospective investigation was carried out on patients who visited our hospital's outpatient department. A general anaesthetic and brachial plexus block were delivered throughout the patients' procedures. Each operation was performed by the same team, which was proficient in both approaches. The study conducted t-test and Chi-square to analyze the data.
Results: The analysis found no significant demographic differences between the two groups (p>0.05). The non-operative group had significantly lower blood loss (71.8±10.5 ml) than the locking plate group (134.2±16.9 ml, p=0.000). Visual analog score (VAS) and Constant-Murley scores indicated greater shoulder function improvements for the locking plate group at three months (p<0.001), although no significant differences were observed at the final follow-up (p>0.05). Postoperative complications did not significantly differ between groups (p=0.337).
Conclusions: Locking plates reduce fractures faster than interlocking intramedullary nails. Both internal fixation techniques for proximal humerus fracture had similar pain and shoulder function scores.
Utility of distal palmar flap in the reconstruction of distal thumb injury
Authors: Rajput D. U. , Kalyanpur Varsha
Published: December 2024

Selecting the most appropriate technique for thumb reconstruction depends on multiple factors, including level of injury, status of the remaining hand, age, occupation, overall health, and functional demands of the patient. In this study we used distal palmar flap for reconstructing distal tissue loss of thumb in patients. It was noted that such defects could be treated effectively with regional flap i.e. distal palmar flap, which gives good aesthetic outcome and patient satisfaction, Patient satisfaction was found to be better with palmar crease flap for smaller defects than larger defects, however all of the patients graded satisfaction as good (80%) and very good (20%). Distal palmar flap is a good reconstructive method for thumb reconstruction, as it an easier and non-microvascular technique which retains the thumb length, colour, vascularity and appearance of thumb. Thus, can be safely advocated for use as it has no significant complications associated with the technique.
Masquelet technique for infected femur bone defect in low resource setting: a case report
Authors: Simatupang Mario D. , Ario Stevanus I.
Published: December 2024

Our hospital is located on the east edge of Indonesia, in the rural city of Merauke, South Papua. In this setting, procedures to bridge large bone defects are limited. The Masquelet technique is a two-stage orthopaedic procedure to treat large bone defects. This technique has a promising future for treating large bone defects, especially in low-resource settings. A 27 years old male experienced a traffic accident. The patient went unconscious and was brought to a nearby hospital where he underwent open reduction and internal fixation of his right femur open fracture. In the 4th week after the trauma, he was diagnosed with osteomyelitis. After multiple procedures in other hospitals, in the 74th week, he arrived at our hospital in Merauke, South Papua. We used Masquelet technique to bridge the bone gap and treat the osteomyelitis. In the first stage, we did debridement and sequesterectomy, then filled the bone defect with antibiotic impregnated PMMA spacer. After 5 weeks, the infection had subsided and the second stage of Masquelet technique was done. We removed the spacer while preserving the membrane and filled the gap with iliac bone autograft and allograft mixture. Union was attained 56 weeks after stage 2. The patient and family are satisfied with the outcome. Masquelet technique is a promising technique with a good success rate for large bone defects, especially in infected bone cases. No need for microvascular and other specialized tools made Masquelet technique can be done in a low-resource setting.
Clear cell carcinoma of minor salivary gland: A clinical impasse
Authors: Gupta Kavita , Khamesra Mansi , Sharma Sourabh , Garg Bhavana , Nikhra Pawan
Published: December 2024

Clear cell carcinoma of minor salivary gland is an exceedingly rare and a low grade malignant neoplasm. It represents approximately 1% of all salivary gland tumors and 0.2% of minor salivary glands. This paper presents a case of intra-oral clear cell carcinoma originating from the minor salivary gland of the palate in a 32-year-old female patient. This case underscores the significance of considering clear cell carcinoma in the differential diagnosis of oral lesions and highlights the necessity of thorough diagnostic and therapeutic strategies.
Mature midline teratoma arising within a posterior thoracic myelomeningocele in an infant: A case report
Authors: Adamu Zainab Ali , Waziri Garba Dahiru , Sani Kamarudeen Owolabi , Gazali Yusuf Kalli , Mohammed Abdullahi
Published: December 2024

Myelomeningocele can occur throughout the spinal axis but the area with the least common localization is the thoracic region which is uncommon. Rarely, these abnormalities coexist with a teratoma and only few reports of a teratoma arising from a myelomeningocele have been reported. Teratoma can also undergo malignant transformation to a non-germ cell malignancy. Here, we report an interesting case of a teratoma arising within thoracic myelomeningocele in an infant.

A three month old girl born via vaginal delivery to two related Fulani parents presenting with upper back swelling noticed since birth. Pregnancy was claimed to be uneventful, mother never attended any antenatal clinic and delivery was at home. On examination patient was mildly dehydrated and malnourished. Status localis revealed an intact cystic midline upper back swelling measuring about 6x4cm, non-tender with no differential warmth. Radiographic evaluation was not done due to financial constraint.

Grossly, three irregularly shaped firm to cystic to flabby tissues aggregating to 5x4x1.5cm, weighing 6g were received and microscopy revealed histologic features of a myelomeningocele with a teratoma having endodermal (respiratory epithelium, seromucinous glands) , ectodermal( skin) and mesodermal (cartilage) components.

Teratoma is a germ cell neoplasm that contains differentiated elements derived from all three germ layers. The occurrence of a mature midline teratoma within a myelomeningocele is rare and what makes it even rarer is occurrence in the thoracic region. This can be confirmed by meticulous histopathologic evaluation.

Myelomeningocele has variable prognosis based on localization and other accompanying abnormalities. Due to the risk of malignant transformation to non-germ cell tumours in teratoma, prompt histologic diagnosis and complete resection is important regardless of size of lesion and age of patient.
A rare location of Pyogenic granuloma in the nasal vestibule in a male patient- A case report
Authors: Gupta Manish , Goyal Isha , Padda Rishab , Kaur Jasmeet
Published: December 2024

Pyogenic granuloma (PG) is a benign lesion of vascular origin with a bleeding tendency. The head and neck region is a common location for its origin, but the nose-borne lesions are rarely seen. They usually grow due to hormonal imbalance as in pregnancy or local trauma. They grow with hyperplastic activity of the skin and mucous membranes. They are more commonly seen in women. For the nasal pyogenic granulomas, unilateral epistaxis and nasal blockage are the common presenting complaints. Surgical excision is the main stay of treatment and if done meticulously, the chances of recurrence are low.

We report a case of 52-year-old male who presented with complaints of recurrent epistaxis from the right nostril. On examination, a dark red polypoidal lesion was noticed in the nasal vestibule. Under local anaesthesia, complete surgical excision of the lesion with cauterisation of the base was done. Histopathological examination of the excised biopsy validated the diagnosis of pyogenic granuloma.

Pyogenic granuloma should be considered as one of the differential diagnosis in the patients presenting with recurrent nasal bleeds, especially in cases of nasal trauma. All the cases likely to be pyogenic granuloma on clinical findings should be excised surgically and evaluated histo-pathologically to rule out any malignancy.
Formy i sposoby wyrażania oporu w wybranych tekstach polskich zespołów alternatywnych lat osiemdziesiątych XX wieku
Authors: Zinkiewicz Grzegorz
Published: December 2024

Celem artykułu jest ukazanie form i strategii oporu w ostatniej dekadzie istnienia Polskiej Rzeczpospolitej Ludowej. Ze względu na charakter tekstu, mnogość wcześniejszych badań i perspektywę badawczą pominięto rolę najbardziej rozpoznawalnych instytucji i organizacji politycznych, które przyczyniły się do upadku systemu totalitarnego w Polsce, wyeksponowano natomiast muzykę alternatywną i rockową jako środki wyrażania oporu. Próba syntezy została podjęta na podstawie zagadnień, takich jak: przedłużona liminalność, ambiwalencja kodu i mechanizmy działania systemu. W części analitycznej przedstawiono interpretację tekstów i dekonstrukcję warstwy muzycznej utworów dwóch zespołów nowofalowych – Kultu i Republiki (płyta Nowe sytuacje), w odniesieniu do zagadnienia oporu.
Fatimka, parapet, skórka – wstępna charakterystyka żargonu organistów (badanie pilotażowe)
Authors: Parafińska-Korybska Ewelina
Published: December 2024

Artykuł podejmuje tematykę niezgłębianą dotąd w badaniach językoznawczych. W ramach wstępu omówiono charakterystykę zawodu organisty na podstawie dokumentów Kościoła katolickiego. Następnie zwrócono uwagę na brak zgodności badaczy w zakresie stosowania pojęć „żargon”, „profesjolekt” i innych do określania nieoficjalnego języka grup zawodowych i społecznych. Na potrzeby artykułu przyjęto termin „żargon”. Źródłem jednostek leksykalnych do omawianych badań była własna wiedza autorki oraz konsultacje z organistami. Wyodrębniono i omówiono siedem klas tematycznych wyróżnionych w tej pracy. Podano liczne przykłady i w wielu przypadkach semantyzację. Odwołując się do materiału, podjęto próbę sformułowania funkcji żargonu organistów. Oprócz funkcji wymienianych powszechnie przy omawianiu żargonu wskazano dodatkowo dystansowanie się od poważnego charakteru wykonywanego zawodu oraz trudności napotykanych podczas pracy.
Melatonin Alleviates Biochemical, Hormonal and Histoarchitectural Alterations in a PCOS Rat Model Exposed to Constant Light by Enhancing Antioxidative Enzymes
Authors: Purohit Adyasha , Hajam Younis Ahmad , Rai Seema
Published: December 2024

The study evaluated the impact of pineal hormone (melatonin) on reproductive impairment induced by constant light/ photoperiodic stress in female Rattus norvegicus. The experimental design consisted of 24 female rats weighing 170 ± 10 gm. The 24 rats were divided into two major groups comprising 12 rats each. Rats in one group were kept under constant light (600 lux) for 60 days to induce PCOS. After confirmation of PCOS by regular observation of vaginal smear, rats in each group were further divided into 2 groups containing 6 rats in each. 12 rats with no treatment were divided as control (0.9% saline) and melatonin (200μg/100gm bw). Rats exposed to the constant light were divided into LL (PCOS) and PCOS+MEL with six rats in each group. After 21 days, the rats were sacrificed, and their ovaries and oviducts were harvested. Blood samples were collected for corticosterone and melatonin, androgen and estradiol analysis, and harvested tissues were stored at -800c for further assessment. The results showed that polycystic ovary rats exhibited increased body weight and anti-oxidative enzyme levels. However, the polycystic ovary rats, that were treated with melatonin showed recovery with melatonin, corticosterone, body and tissue weight, and biochemical parameters. The study suggests that continuous light exposure can induce reproductive disorder by disrupting GnRH rhythmicity, but melatonin treatment restores reproductive homeostasis. The study provides insights into polycystic ovary syndrome pathogenesis and the potential therapeutic benefits of melatonin.
Trilhas brincantes acadêmicas: das escolhas e dos deslocamentos
Authors: Habowski Adilson Cristiano
Published: December 2024

Neste texto, apresento as trilhas brincantes acadêmicas que percorri no Programa de Pós-Graduação em Educação da Universidade La Salle, que celebra uma década de doutorado em 2024. Trata-se de um gesto comemorativo ao programa através do compartilhamento e problematização de algumas das experiências acadêmicas que vivi no decorrer da Iniciação Científica, Mestrado e Doutorado em Educação, e atualmente com o estágio pós-doutoral (CNPq). Circunscrevo-me com mais ênfase ao relato da minha pesquisa de mestrado, a transformação da dissertação em um livro, e os deslocamentos que emergiram no decorrer da tese de doutoramento. A partir disso, discutirei os redirecionamentos dados no doutoramento, diante das novas intenções e enfoques, considerando o interesse em explorar outras ferramentas analíticas e opções teóricas e metodológicas para examinar com uma nova perspectiva o meu foco de pesquisa: as crianças e as tecnologias digitais. Por fim, apresento os novos interesses de pesquisa agora enquanto pós-doutorando com bolsa do CNPq junto a este programa e as temáticas em investigação enquanto docente colaborador do PPGEdu da Universidade Regional Integrada do Alto Uruguai e das Missões (URI). Para além do gesto comemorativo aos dez anos de comemoração ao doutorado do PPGEdu, trata-se de compreender a experiência da escrita como um processo de autoformação, no qual o sujeito se cultiva ao olhar para sua própria trajetória de vida. Ao narrar suas experiências, o que foi experimentado se transforma em escrita que não apenas registra, mas também ajuda a compreender melhor seu percurso e a se tornar quem é.
Imagem corporal de docentes com deficiência
Authors: Souza Mariana Pinkoski
Published: December 2024

A sociedade contemporânea neoliberalista busca incessantemente padrões para que as pessoas se encaixem, na busca pelo reconhecimento e homogeneidade, já as vertentes humanistas, construtivistas e que defendem a inclusão vão contra ao que é idêntico e sim a favor da diferença. O objetivo deste estudo é compreender como é a imagem corporal de docentes universitários com deficiência atuantes em universidades comunitárias do sul do Brasil. A metodologia foi baseada na Hermenêutica de Gadamer através de entrevistas com docentes com deficiência das universidades comunitárias do Sul do Brasil constituintes do Comung. Os resultados demonstram que os docentes percebem suas imagens corporais diferentes e lutam para que a universidade e a sociedade acolham as diferenças, bem como sabem que existe um padrão mas ele deve ser quebrado para que a humanidade venha antes de quaisquer características que fujam da homogeneidade e ocorra a desconstrução e a disrupção de um padrão corporal contestável.
Inclusive growth in rural Indonesia: exploring the tnteraction between technology and financial inclusion
Authors: Shofi Dana Badara
Published: December 2024

Financial inclusion, as a form of ease in accessing financial services for the community, is key to creating inclusive growth. This research examines financial inclusion and technology in influencing inclusive growth in rural areas of Indonesia. The analytical approach is a Longitudinal Data Panel. The data is sourced from the Indonesia Family Life Survey (IFLS). The results of this study indicate that financial inclusion influences inclusive growth. On the other hand, technology plays an intermediate role between financial inclusion and inclusive growth in rural areas of Indonesia. The government also needs to provide facilities and security to develop technology.
Application of Istishna to buying and selling furniture (case study of Sambi Tereng gallery shop)
Authors: Amelia Jannati Rizka , Ahmad Amir Aziz  , Muhammad Azkar
Published: December 2024

This study aimed to determine the application of istishna' in buying and selling furniture at the Sambi Tereng Gallery Shop. The approach used in this research is a qualitative approach which produces descriptive data. Data collection techniques in this research used observation, interviews and documentation. The informants in this research consisted of 1 key informant, 3 main informants, and 3 additional informants. The technique for checking the validity of the data used by the author in this research was the triangulation technique. The results of this research show that the application of istishna' in buying and selling furniture at the Sambi Tereng Gallery Shop has been applicated in accordance with the pillars and requirements of istishna'.
Strengthening business capital in the Halal industry through Waqf: ANP analysis of the Waqfpreneur program
Authors: Sujono Rusny Istiqomah
Published: December 2024

This study examines how the Indonesian Waqf Education Foundation's Waqfpreneur program strengthens business capital in the halal industry through the waqf mechanism. The halal industry in Indonesia has experienced significant growth but still faces challenges in terms of financing and business capital. Waqf, as an Islamic financial instrument, offers a potential solution to overcome this problem. The Waqfpreneur program is an innovation in waqf management that aims to support halal industry entrepreneurs by providing business capital through a productive waqf scheme. This study employs the Analytic Network Process (ANP) method, enabling a thorough assessment of multiple factors that impact the program's success. The study's results show that the main benefit of strengthening business capital through waqf is avoiding Riba capital, while the main opportunity is expanding the Indonesian halal industry market. Next, we must consider the cost of waqf management, taking into account the full value of the waqf. In the halal industry, compliance with halal standards poses the main risk.
Methods for calculating specific electrical conductivity of the LiF+NaF mixtures melt
Authors:   Samara State Technical University, Lavrenteva Olga V. , Garkushin Ivan K. ,   Samara State Technical University, Nikitina Alina S. ,   Samara State Technical University
Published: December 2024

The calculation of the specific electrical conductivity of lithium and sodium fluorides mixtures melts is presented. The Iinterest in the
LiF–NaF system melts is determined by their practical significance. Melts of LiF+NaF mixtures are used in heat-storing compositions and in metallurgy. They are part of various multicomponent systems. The specific electrical conductivity calculation by isoconcentration, isothermal and interpolation methods is given for LiF+NaF mixtures melts of various compositions using known reference data for the temperature range 1020...1340 K.
A calculation has been performed for the eutectic composition. The resulting analytical equations have been used to describe and calculate the specific electrical conductivity of the eutectic mixture for temperatures 5°, 10°, 50°, 75°, 100° above the liquidus. The specific electrical conductivity of the eutectic mixture melt is calculated on isotherms by interpolation for the isoconcentration dependences of hypoeutectic and
hypereutectic mixtures. Isotherms of electrical conductivity (1020...1340 K) of melts depending on the content of LiF and NaF components
are described by a third-degree polynomial. Depending on the temperature, the coefficients in the resulting equation change linearly. A comparison has been made of the values of specific electrical conductivity ϰ(LiF+NaF), calculated from the obtained equations. The description
of ϰ(LiF+NaF) by isoconcentration and isothermal methods has showed satisfactory convergence of calculation results and makes it possible
to calculate the specific electrical conductivity of LiF+NaF mixtures melts of any given composition, including eutectic.
Study of the influence of various physiologically active substances on changes in the lipid composition and phospholipase activity of damaged somatic nerves
Authors:   National Research Ogarev Mordovia State University, Revin Viktor V. , Parchaykina Marina V. ,   National Research Ogarev Mordovia State University, Chudaikina Elena V. ,   National Research Ogarev Mordovia State University, Revina Elvira S. ,   National Research Ogarev Mordovia State University, Molchanov Ivan D. ,   National Research Ogarev Mordovia State University, Simakova Milena A. ,   National Research Ogarev Mordovia State University, Zavarykina Anastasia V. ,   National Research Ogarev Mordovia State University, Grunyushkin Igor P. ,   National Research Ogarev Mordovia State University, Devyatkin Arkadiy А. ,   National Research Ogarev Mordovia State University
Published: December 2024

The changes in lipid composition and phospholipase activity in damaged somatic nerves were studied against the background of
the action of potassium hyaluronate and insulin-like growth factor-1. It has been shown that nerve cutting is accompanied by an increase in
phospholipase A2 activity, resulting in an accumulation of lysophospholipids and free fatty acids, as well as an increase in phosphatidylinositol
levels and a decrease in diacylglycerol content, which is most likely due to inactivation of phosphoinositide-specific phospholipase C against the
background of injury to the nerve conductor. The introduction of potassium hyaluronate and insulin-like growth factor-1 enhances the recovery
processes in the injured nerve conductor, however, the mechanisms of their action remain different. According to the literature data and the
results of our own research, the action of potassium hyaluronate and insulin-like growth factor-1 is realized as a result of the launch of signaling
pathways associated with the regulation of the activity of enzymes from the phospholipase family. At the same time, our data on a decrease
in the activity of phospholipase A2 and the absence of significant changes in the level of phosphatidylinositol and diacylglycerol indicate that
potassium hyaluronate most likely exerts its effect through the PL A2-mediated pathway. In addition, it was shown that against the background
of the action of IGF-1, an intensification of phosphoinositide metabolism is observed, which is explained by the activation of phosphoinositidespecific phospholipase C. According to the literature, the launch of the phospholipase C-mediated mechanism is accompanied by the formation
of components of the phosphatidylinositol 3-kinase signaling pathway involved in stimulation of the expression of various transcription factors
necessary for axonal regeneration and restoration of the functioning of injured nerve conductors.
Ektacytometry: Characterization of erythrocytes of residents of KhMAO-Yugra treated with natural zeolites
Authors:   Tyumen State Medical University, Vokhmintsev Andrei P.
Published: December 2024

The effect of a diet containing natural zeolite (clinoptilolite) on the deformability of red blood cells of volunteers of both sexes,
of a wide age range living in KhMAO-Yugra (Khanty-Mansiysk), was studied. Natural zeolites, according to literature data, have antioxidant,
membrane-protective and hematostimulating properties. It has been shown that the use of zeolite powder by volunteers for 30 days causes
an increase in the erythrocyte deformability index (determined by laser diffractometry) compared to measurements taken before the start of
the study. Such changes were the result of a significant increase in erythropoiesis and a decrease in lipoperoxidation processes. The results
obtained indicate the multifaceted role of zeolites in ensuring the normal functioning of the human body living in areas with uncomfortable
climatic and geographical conditions.
On the status of plant populations in the South of the Middle Volga region (Russia) from the Annexes of the “Convention on International Trade in Endangered Species of Wild Fauna and Flora”
Authors:   Samara Federal Research Center of the Russian Academy of Sciences, Institute of Ecology of the Volga Basin of the Russian Academy of Sciences, Vasjukov Vladimir M.
Published: December 2024

The article provides information on the current status of populations of 29 plant species from the Orchidaceae family in the south
of the Middle Volga region (within the Penza, Samara and Ulyanovsk regions) from Annex II of the Convention on International Trade in
Endangered Species of Wild Fauna and Flora (CITES): Cephalanthera longifolia (L.) Fritsch, Cephalanthera rubra (L.) Rich., Corallorhiza trifida
Chatel., Cypripedium calceolus L., Cypripedium guttatum Sw., Cypripedium macranthos Sw., Cypripedium ventricosum Sw., Dactylorhiza fuchsii (Druce)
Soo, Dactylorhiza incarnata (L.) Soo, Dactylorhiza maculata (L.) Soo, Dactylorhiza russowii (Klinge) Holub, Dactylorhiza viridis (L.) R. M. Bateman,
Pridgeon et M. W. Chase, Epipactis atrorubens (Hoffm.) Besser, Epipactis helleborine (L.) Crantz, Epipactis palustris (L.) Crantz, Epipogium aphyllum Sw., Goodyera repens (L.) R. Br., Gymnadenia conopsea (L.) R. Br., Hammarbya palu dosa (L.) Kuntze, Herminium monorchis (L.) R. Br., Liparis
loeselii (L.) Rich., Malaxis monophyllos (L.) Sw., Neotinea ustulata (L.) R. M. Bateman, Pridgeon et M. W. Chase, Neottia nidus-avis (L.) Rich.,
Neottia ovata (L.) Bluff et Fingerh., Orchis militaris L., Platanthera bifolia (L.) Rich., Platanthera chlorantha (Custer) Rchb., Ponerorchis cucullata (L.)
X. H. Jin, Schuit. et W. T. Jin.
Unicorns of our Middle Ages. Scribes of the Land Courts of Ruthenian and Podolian Voivodeships in 1434–1500
Authors: Mykhaylovskiy Vitaliy
Published: December 2024

The article analyzes the quantitative composition, qualifications, regions of origin, and work experience of scribes in the land courts of the Ruthenian and Podolian Voivodeships from 1434 to 1500. The Ruthenian Voivodeship included the land courts of Lviv, Przemyśl, Halych, and Sanok, while the Podolian Voivodeship encompassed the Kamyanets land courts. A unique feature of the Ruthenian Voivodeship was the visiting sessions of the Przemyśl land court in Przeworsk and, presumably, of the Lviv land court in Zhydachiv. This study revises, supplements, and clarifies the existing list of land scribes in these voivodeships, drawing on newly discovered data and a re-examination of all available references to these officials. The article focuses on the earliest references to the scribes’ appointments in both voivodeships, their experience in governance or as scribes in other institutions, their educational background, regions of origin, and the frequency of references to their governance. Notably, given the shortage of qualified personnel, individuals from the Catholic Church, who often had the requisite knowledge of Latin, were recruited to fulfill governmental roles, thus combining zemstvo governance with their pastoral duties. A particularly remarkable figure is Mykolay from Pyashchytsi, a Kamyanets zemstvo scribe, who concurrently served as a personal scribe to the Starosta and as the Vogt of the Ruthenian community in Kamyanets. In the late Middle Ages, the skill of writing was rare in the Ruthenian territories of the Kingdom of Poland. Those who could draft Latin documents for courts where proceedings occurred in both Ruthenian and Polish were highly valuable.
Understanding the Greenium between Green and Conventional Bonds: A Simulation Study
Authors: Traore Abdelmoumine
Published: December 2024

This paper examines the pricing disparity between green and conventional bonds (the greenium), drawing on empirical research findings that have yielded mixed re- sults. We introduce a mathematical model to elucidate the conditions under which green bonds may be priced differently from their conventional counterparts. Un- like previous studies primarily focused on firm-level characteristics, our model incor- porates investors’ prosocial attitudes, income levels, and risk preferences to derive market prices for green bonds. By considering both supply and demand dynamics, we pioneer an equilibrium-based approach to pricing, departing from the assump- tions of traditional models like CAPM and Black-Scholes. Additionally, we integrate regulatory risk into our analysis, introducing the concept of ”green default” along- side pecuniary default. Our findings underscore the influence of investors’ prosocial preferences, issuer environmental commitments, and issuance costs on the greenium. Moreover, stringent environmental policies and advancements in green technology mitigate the likelihood of green default, thereby bolstering market demand for green bonds. While climate risk exerts downward pressure on bond prices overall, its im- pact on the greenium varies based on the relative reduction in the equilibrium price of green bonds compared to conventional bonds.
Passivity Based Control of Doubly Fed Induction Generator Using an Interval Type-2 Fuzzy Logic Controller
Authors: Allali Izzeddine , Dehiba Boubekeur
Published: December 2024

The article is interested in the control of a Doubly Fed Induction Generator (DFIG) for wind energy conversion. The proposed structure is based on the association of passivity and interval type 2 fuzzy logic control. The principal objective of this task is to effectively regulate and optimize the flow of both active and reactive power from the generator to the interconnected network to ensure efficient operation and stability, with the rotor signals operated via a bidirectional converter. The proposed control technique is subjected to various conditions to evaluate its performance, including varying wind speeds and parameter adjustments. The simulation results show the robustness of the proposed control, where the integration of the interval type 2 fuzzy logic controller (IT2-FLC) enhances the dynamic performance, disturbance sensitivity, and robustness against parameter changes.
EVALUATION OF THE ANIONIC POLYMER ADDITION IN THE CLARIFICATION OF REAL EFFLUENT FROM THE HYDROPHILIC COTTON BLEACHING
Authors: Heymannz Bitencourt Daynara , Bortolotto Ricardo , Costa Tania Maria
Published: December 2024

Water, essential for maintaining life, is widely used in industrial processes, generating high volumes of industrial liquid effluents. These, if not treated properly end up contaminating water bodies and causing serious damage to the environment. Among the technologies applied to industrial effluent treatment, physical-chemical treatments are usually accompanied by auxiliary products. In this context, the present work aimed to evaluate the influence of anionic polyacrylamide addition as a coagulation aid of industrial effluent clarification from the bleaching process of cotton hydrophilic. Based on preliminary assays, a Central Rotational Composite Design (DCCR) was developed for the coagulant/flocculant combination, evaluating pH, turbidity, and color. The results obtained showed that anionic polymer improved the treatment performance, forming larger, heavier, and more stable flakes, which resulted in better removal of turbidity (29.7%) and color (33.09%) when compared to the treatment without its addition (22% and 25%) respectively. They also speed up the decanting process, reducing the consumption of primary coagulant and contributing to the effluent parameters being following the discharge standards stipulated by legislation, proving its efficiency as a coagulation aid.
Diabetic ketoacidosis induced by SGLT2 inhibitors in acute ischemic stroke: a report of two cases
Authors: Jeong Jin-Heon
Published: December 2024

Background: Diabetic ketoacidosis (DKA) is a common hyperglycemic emergency characterized by hyperglycemia, metabolic acidosis, and ketonemia. DKA is a rare but serious complication of sodium-glucose cotransporter-2 (SGLT2) inhibitors that requires careful monitoring.Case Report: We present two cases of acute ischemic stroke in patients who developed DKA during the administration of SGLT2 inhibitors. Case 1 was a 70-year-old woman with a right middle cerebral artery (MCA) infarction who developed severe metabolic acidosis and ketonemia on hospital day 5, which resolved after insulin and fluid therapy. Case 2 was a 52-year-old woman with a right MCA infarction and carotid stenosis who developed DKA on hospital day 3. Despite initial resolution, DKA recurred after SGLT2 inhibitor re-administration and permanent discontinuation was necessary.Conclusion: These cases highlight the risk of DKA in the acute phase of ischemic stroke in patients treated with SGLT2 inhibitors.
Disciplina y controles escolares en Cuba desde los discursos de ciencia (1880-1898)
Authors: Núñez Yoel Cordoví
Published: December 2024

El artículo tiene como objetivo principal analizar los enfoques pedagógicos relacionados con la disciplina y los controles escolares, a partir de los aportes de diferentes ramas de las ciencias que, con grado dedesarrollo variables, contribuyeron a perfeccionar la gestión profesoral de las conductas en las instituciones educativas cubanas. El texto se estructura atendiendo al influjo de aquellas disciplinas de mayor relevancia en el campo de la pedagogía relacionado con las conductas y regulaciones del orden en las instituciones escolares; tanto desde la sociología, como de los aportes de la psicología – todavía en cierne – la fisiología, la higiene y, desde luego, de las propias técnicas pedagógicas concebidas en la época. En cada sección, se asiste a la comprensión de las diferentes maneras de concebir la naturaleza de la corporalidad infantil, no como elemento inmutable, sino como construcción histórica condicionada según los diferentes contextos económicos, políticos, sociales y culturales. El contenido se enmarca entre los años 1880, coincidente con el fracaso de la primera guerra de liberación en Cuba, e inicio de un período de intensos debates sobre el tema, y el fin de la dominación española en 1898.
Characteristics of fuel oil from the Krapivinskoe field (Part 1)
Authors: Cheshkova Tatyana V. , Sagachenko Татyana А. , Cherednichenko Kirill A. , Vishnevich Alexandra S. , Min Raisa S.
Published: December 2024

Relevance. The need to obtain information about the chemical nature of the resin-asphaltene and oil components of atmospheric residue from distillation of crude oil produced at the Krapivinskoe field in order to select optimal technologies for its rational utilization. Aim. To study the structures of asphaltene macromolecules and resin substances and the molecular composition of the oil components of atmospheric residue from distillation of crude oil produced at the Krapivinskoe field. Methods. Transmission electron microscopy, X-ray phase analysis, IR spectroscopy, 1H NMR spectroscopy, structural group analysis, chemical destruction, gas chromatography-mass spectrometry. Results. The structure of resin-asphaltene substances and the molecular composition of atmospheric residue obtained in the course of atmospheric distillation of oil from the Krapivinskoe field in laboratory conditions have been characterized using a complex of physicochemical research methods. It was found out that asphaltenes of atmospheric residue have a predominantly amorphous structure because of the presence of a developed alkyl chain configuration in their macromolecules. Mean asphaltene molecules consist of three structural blocks, which basis is triarene cores condensed with four to five naphthenic rings. These naphthenoaromatic systems neighbor upon methyl substituents only. The mean molecules of atmospheric residue resins are predominantly single-block. Their structural blocks are more compact due to the smaller number of aromatic and naphthenic rings in the naphthenoaromatic system. A feature of mean resin molecules is also the presence of relatively long alkyl substituents in the blocks. It was established that the structure of asphaltenes and atmospheric residue resins contains fragments linked to each other or to the naphthenoaromatic core of their macromolecules through sulfide and ether bridges. In both types of ‘linked’ fragments, n-alkanes, n-alkylcyclohexanes and hopanes were identified. Among the fragments linked through sulfide bridges, n-alkylbenzenes, n-alkylmethylbenzenes and n-alkanoic acids were additionally identified, while ethyl esters of n-alkanoic acids were identified among fragments linked through ether bridges. A structural feature of the atmospheric residue resins is the presence of phenylalkanes with different positions of the phenyl substituent in both types of bridge-linked compounds. Steranes and phenanthrenes are present in the composition of compounds linked through sulfide bridges. The oil components of atmospheric residue contain n-alkanes, n-alkylcyclohexanes, hopanes, steranes, n-alkylbenzenes, n-alkylmethylbenzenes, alkylnaphthalenes and alkylphenanthrenes.
Comparative analysis of numerical modeling of methods for intensifying inflow to the well, including hydrochloric acid treatment
Authors: Bychkov Denis A. , Zyatikov Pavel N.
Published: December 2024

Relevance. The need to enhance oil recovery from horizontal wells under complex geological and technical conditions. The use of more accurate numerical models, including chemical reactions and the modeling of complex fracture systems, allows optimization of well stimulation, significantly improving both economic and technological efficiency. This is particularly important for developing low-permeability reservoirs and operating under challenging conditions. This work examines the numerical modeling of well inflow stimulation methods using various approaches. For acid treatment modeling, approaches based on changes in well productivity and the use of chemical reactions in the hydrodynamic model were applied. The quality of forecasted technological performance was assessed using real data from an analogous well. As a result, in the case of a real field with extended horizontal wells, additional oil production was achieved through different approaches to acid treatment modeling. Multistage hydraulic fracturing was modeled using planar and discrete fracture models, with only minor discrepancies in the hydrodynamic modeling results between these methods. Aim. To assess the effectiveness of various numerical modeling approaches for well inflow stimulation methods, such as acid treatment and aimed at optimizing oil production from extended horizontal wells. Methods. Numerical models were used to evaluate the effectiveness of stimulation methods, focusing on changes in productivity, the impact of chemical reactions, and sensitivity analysis of treatment parameters. Results and conclusions. It was found that the use of negative skin factors significantly increases oil production compared to models accounting for chemical reactions. Sensitivity analysis of acid volume and concentration helped identify optimal parameters for enhancing acid treatment efficiency. Both modeling approaches (planar and discrete fracture systems) yielded comparable results. Multistage hydraulic fracturing demonstrated a 25000-ton increase in oil production over three years, making it a more effective method than acid treatment.