bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence and risk factors associated with hypertension among the Hmong people in Phayao Province, Thailand
Authors:   Department of Community Health, School of Public Health, University of Phayao, Mueang, Phayao, Thailand, Promma Natnapa
Published: December 2024

Hypertension is a significant global public health issue, including in Thailand. Research findings are still lacking among vulnerable populations in remote areas, with particular emphasis on the Hmong ethnic group. The data obtained from the research can be utilized to plan and develop tailored and effective health policies for specific ethnic groups, thereby enhancing the efficiency of hypertension management. This cross-sectional study aimed to investigate the prevalence and risk factors of hypertension among the Hmong tribe in Phayao province. The study sample comprised 380 individuals using a multi-stage sampling method from the Hmong ethnic group aged 20 years and older. This study was a face-to-face interview. Data were analyzed using descriptive statistics, Chi-square test, and multiple logistic regression. The results showed that 32.9% of the respondents had hypertension based on home blood pressure measurements (135/85 mmHg). The average systolic blood pressure (SBP) was 125.69 mmHg and diastolic blood pressure (DBP) was 78.61 mmHg. In the multiple logistic regression analysis, the significant factors associated with hypertension were stress (Adj.OR:0.26; 95%CI 0.12-0.57; p=0.001), sugar consumption (Adj.OR:4.21; 95%CI 2.44-7.28; p<0.001), and salt consumption (Adj.OR:2.00; 95%CI 1.15-3.42; p=0.014). Health centers should conduct regular screening for hypertension and develop innovations in promoting appropriate dietary behavior modifications (specifically sugar and salt intake) with culturally tailored communication materials for the Hmong tribe to address the problem effectively and sustainably.
Kajian Ekoliterasi Lingkungan: Sikap Islam Terhadap Lingkungan Karya M. Quraish Shihab Dalam Buku Islam dan Lingkungan (Perspektif Al-Quran Meyangkut Pemeliharaan Lingkungan)
Authors: Nurullah Sururi
Published: December 2024

Kerusakan Alam tidak pernah lepas dari faktor penghuninya. Dalam titik ini, manusia sebagai khalifah di muka bumi patutlah menjadi sorotan utama kerusakan lingkungan. Hal itu kemudian agar tidak berkelanjutan agama menyikapinya dengan berbagai tuntunannya dalam kitab suci. Islam dalam kitab suci Al-Qur’an juga begitu jelas sekali perihal menjaga alam. Namun mayoritas muslim malah tidak menyadari atau memahaminya secara benar. Atas keberadaan demikian, buku Islam & Lingkungan (Perspektif Al-Quran Meyangkut Pemeliharaan Lingkungan) hadir sebagai upanya menunjukkan kejelasannya. M. Quraish Shihab sebagai penulis buku itu, langsung mengambil berbagai ayat untuk ditampakkan, salah satu intinya yang amat tampak terdiri dari enam ayat.
Water Distribution Performance Assessment For Seydişehir Irrigation Association
Authors: Fişekçioğlu Üstün Fulya
Published: December 2024

Bu çalışmada Konya İli, Seydişehir İlçesinde bulunan Seydişehir Sulama Birliği alanındaki sulama şebekesinin 2019-2023 yıllarına ilişkin performansını belirlemek amacıyla yürütülmüştür. Bu kapsamda performans incelemesinde şebekeye alınan su miktarıi,sulama oranı, birim alana dağıtılan yıllık sulama suyu miktarı, birim sulanan alana dağıtılan yıllık sulama suyu miktarı incelenmiştir. Sulama şebekesine en fazla su 2019 yılında alınmış olup en az su ise 2021 yılında kullanılmıştır. Yıllar içerisinde en yüksek sulama oranı %52,85 ile 2021 yılında gerçekleşirken bu oranın en düşük olduğu yıl %34 ile 2019 yılına aittir. Hektar başına sağlanan suyun en fazla olduğu yıl 2022 yılı iken en az yıl 2019 yılıdır. Birim sulanan alana dağıtılan yıllık sulama suyu miktarı en yüksek 17016,83 m³/ha ile 2019 yılı iken en düşük 2637,79 m³/ha ile 2021 yılında gerçekleşmiştir. Her bir su damlasının değeri ve kritik rolünün arttığı günümüzde su tasarrufunu suyu en yoğun kullanan tarım sektöründen başlayarak hayatımızın her alanına yaymak çevre, ekosistem ve insan yaşamı açısından son derece önemlidir. Bu yüzden tarımsal üretimde su kaynak kullanımının doğru planlanması bu önemli sorumluluğu üzerine alan sulama birliklerinde performansların değerlendirilmesi büyük önem arz etmektedir.
Solving Systems of Linear Algebraic Equations Using the Monte Carlo Method
Authors: Anwari Mohammad Asghar , Rahnawadr Ahmad Ramin
Published: December 2024

Mathematics is a vast science that has developed in different parts according to human needs and at different times to solve human problems since its inception. The branches of mathematics can be considered as an independent field due to their complexity. Numerical calculations or numerical analysis, in turn, can be found in different parts due to the calculations of equations that do not have real solutions. It can find their numerical solutions.
Numerical analysis can be used in various areas such as power calculations, logarithms, limit calculations, numerical derivatives of functions, numerical integrals, etc. mathematical calculations. In this regard, mathematicians have conducted research in various areas and after a period of time have reached a solution to the problem at hand and have left a mark in the form of various relations, formulas, and theorems, each of which has created convenience for the reader. One of these methods that can easily solve equations is solving a system of linear equations using the Monte Carlo method. Basically, this method, with its complexity, considering probabilistic calculations and obtaining the prices of a system and using mathematical hope, can easily solve a system of linear algebraic equations.
Review on Tradescantia spathacea (Medicinal Plant)
Authors: Kushwaha Shivam , Kukshaal Meenakshi , Patil Shivanand M.
Published: December 2024

Tradescantia spathacea, often known as Moses-in-the-Cradle, is a perennial herbaceous plant of the Commelinaceae family. This species is native to Central America and the Caribbean, and it has grown in favour as an ornamental plant due to its vivid leaf and low maintenance requirements. Aside from its visual attractiveness, T. spathacea has received interest for its medicinal effects and environmental adaptation. This review brings together current studies on its phytochemistry, therapeutic potential, and environmental significance. Key phytochemical ingredients, including flavonoids, saponins, and phenolic compounds, are highlighted for their antioxidant, antibacterial, and anti-inflammatory properties. The plant's involvement in environmental clean-up, notably heavy metal pollution reduction, is also mentioned. Despite its adaptability, issues such as invasiveness and habitat-specific growth requirements necessitate additional investigation. This review is to provide a thorough overview of Tradescantia spathacea, linking its decorative, medicinal, and ecological roles while recommending opportunities for future research and use. T. spathacea is extremely resilient to stress situations, such as poor soils and urban pollution, making it an important component in green infrastructure and phytoremediation programs. Its ability to gather heavy metals and enhance soil quality has been investigated as a possible tool for environmental management. However, its quick spread and adaptability have created worries about its invasive tendencies in some areas, necessitating a cautious approach to cultivation and use.
Effect of humic acid application methods on yield and quality of Mungbean (Vigna radiate L.)
Authors: Javed Muhammad , Tahir Muhammad , Iqbal Asif , Saleem Muhammad Abdullah , Naveed Muhammad Tahir , Kausar Misbah
Published: December 2024

The application methods of nutrients play a pivotal role in enhancing crop production. Soil amendment aids in nutrient fixation, while foliar application may improve penetration through the cuticle, thereby reducing nutrient losses. An experiment conducted at the University of Agriculture Faisalabad from March to June 2017 aimed to evaluate different application methods for humic acid in mung beans using a Randomized Complete Block Design. The treatments included were [H1= Control (dry seed), H2= hydro priming, H3=seed priming with 2% humic acid H4=4% humic acid, H5= 2 kg humic acid ha-1, H6= 4 kg humic acid ha-1, H7=0.1% spray of humic acid and H8=0.2% spray of humic acid. Observations on yield and quality components were recorded by following standard procedures. Results showed that No. of pod bearing branches (7.33), No. of pods per plant (18.00), No. of seeds per pod (9.66), 1000-seed weight (44.00 g), plant height (45.16 cm), seed yield (1487.70 kg ha-1), biological yield (5191.30 kg ha-1), harvest index (28.64 %) and protein contents (25.20 %) were statistically significant in the treatment H6 (4 kg humic acid ha-1). In conclusion, soil application of humic acid, especially at a rate of 4 kg ha-1, significantly increased mung bean yield and quality. The findings suggest that this dose was particularly effective, and future research could explore higher doses to optimize humic acid levels for further enhancing mung bean production.
Low-temperature produced peanut-waste biochar reduced nitrogen and phosphorous fertilizer dependency of maize hybrid Syngenta-6621 in alkaline soil
Authors: Aon Muhammad
Published: December 2024

Slow pyrolyzed, low-temperature (300-350⁰C) produced biochar can be used for improving chemical characteristics of nutrient-deficient alkaline soil, however, the effect of such type of biochar on crop fertilizer demand is poorly understood. Thus, a pot experiment was carried out to determine the optimal nitrogen (N) and phosphorus (P) fertilizer requirements for maize grown in peanut-factory waste biochar (PBC) amended calcareous soil. The experiment used a completely randomized design, where two treatments were applied without PBC: one with no N or P fertilizer (control) and one with the recommended doses of NP fertilizer (N3P3). In addition, sixteen treatments were applied with 1.5% PBC, incorporating all possible combinations of four N fertilizer levels (0%, 33%, 66%, and 100% of the recommended dose, labelled as N0, N1, N2, and N3) and four P levels (0%, 33%, 66%, and 100%, labelled as P0, P1, P2, and P3). The N3P3 treatment served as the baseline for evaluating maize growth stages. Three replicates for each treatment were harvested randomly at the V8 growth stage (after 25 days of germination based on N3P3), while the remaining three replicates were harvested at the V14 stage (after 50 days of germination based on N3P3). At V8, the PBC + N3P2 treatment resulted in a significant increase (24%) in shoot fresh weight compared to N3P3. The highest increases in shoot P concentration (25%) and uptake (20%) were observed in the PBC + N1P2 and PBC + N3P3 treatments, respectively, compared to N3P3. By the V14 stage, the PBC + N2P2 treatment yielded maximum value of dry matter (17.7 g pot−1) and had 18% more shoot dry matter than N3P3. Additionally, this treatment showed the largest improvement (10%) in chlorophyll content. In terms of N, the PBC + N3P0 and PBC + N3P2 treatments had the highest concentration (19%) and uptake (37%), respectively, compared to N3P3. Treatment PBC + N2P2 also recorded the highest P concentration and uptake, with increases of 16% and 34%, respectively, over N3P3. Growth rates were significantly higher when PBC was used without additional N or P fertilizer, compared to the N3P3 treatment. The results at V14 suggest that applying 1.5% slow pyrolyzed, low-temperature PBC can reduce N and P fertilizer requirements by up to 34% without negatively affecting the nutrient content or uptake in fodder maize.
Polymorphism in the P2Y12 Gene & Antiplatelet Response to Clopidogrel in the Pakistani Population
Authors: Ahmed Manzoor , Bangash Muhammad Hanif , Rafique Mehwish
Published: December 2024

Clopidogrel, an antiplatelet drug, is frequently prescribed to patients with cardiovascular disease and those suffering from a stroke. Despite the drug being effective in most patients, some do not respond to the therapy and experience ischemic events early in the treatment, which might be due to poor platelet inhibition. The current study investigates the association between polymorphism in the P2Y12 adenosine diphosphate receptor (ADP) gene and platelet aggregation in response to clopidogrel in a Pakistani cohort. The study comprised 91 patients diagnosed with cardiovascular diseases and treated with clopidogrel. Antiplatelet response to clopidogrel was monitored by an aggregometer. The genotyping of the T744C genetic polymorphism of the P2Y12 receptor gene was carried out using the restriction fragment length polymorphism polymerase chain reaction method. Our results show that 53% of patients were homozygous for the P2Y12 wild-type genotype, 38% possessed one copy of the T allele, and 9% possessed both T alleles. Mean values of inhibition of platelet aggregation were different in all three groups. However, the differences in the means did not reach statistically significant levels. Therefore, we concluded that our study does not show an association between the T744C polymorphism of the P2Y12 ADP receptor gene and platelet inhibition by clopidogrel.
Impact of Ashwagandha in Stress, Depression, and Sports; A Systematic Review
Authors: Alam Fiaz , Rehman Asad Ur , Waheed Hina , Malik Shazia
Published: December 2024

Ashwagandha is a well-known traditional medicine and is a part of many formulations in the Ayurveda medicine system. Besides its many medicinal and nutritional uses, the drug has been prescribed to treat stress and depression. The objective of the study is to comprehensively review the use of Ashwagandha in stress, depression, and sports. Due to the presence of multiple nutrients, it has been employed by sportsmen for stamina and strength. The literature was searched by electronic databases including PubMed, Scopus, Google Scholar, and Web of Science. The published data from 1987 till date was included. Based on needs, traditional reports were also reported beside scientific literature. This review included many scientific studies focusing on the use of Ashwagandha in stress, depression, and sports. It was found in the studies that Ashwagandha has proved its logical use in conditions related to stress, anxiety, depression, stamina, and fatigue. In many cases, Ashwagandha was equipotent to the conventional anxiolytic agents. The most important compounds isolated from Ashwagandha for use in stress and depression were withanolides. In sports-related activities, it was found that Ashwagandha increases the oxygen consumption. It is well established from the scientific literature that Ashwagandha has potent regenerative tonic properties, it has anti-stress, and anxiolytic properties. It increases the stamina of sportsmen and improves their physical performance. Thus, the mentioned results clearly showed that the traditional use of Ashwagandha has a logical and scientific basis.
FT-IR Analysis, Phytochemical Content and Antioxidant Activity of Murraya koenigii Leaf Extracts
Authors: Anwar Javeria , Khan Sana , Anwar Muhammad Asad
Published: December 2024

Murraya koenigii (M. koenigii) which belongs to the family Rutaceae is a medicinal plant that is rich with phytochemicals. Phytochemicals are bioactive compounds that can be used as sources for prevention and treatment of many diseases. This study aims to determine the total phenolic content (TPC), total flavonoid content (TFC), total antioxidant activity (TAA), and characterisation of phytochemicals of the M. koenigii leaves; after applying different drying methods and a variety of solvents for extraction of phytochemicals. Sun-dried, shade-dried, and fresh M. koenigii leaves are employed in the study along with the use of n-hexane, methanol, and distilled water as a solvent for extraction of phytochemicals based on polarity. The maceration method is used for extraction, the Folin-Ciocalteu method for evaluation of total phenolic content, the colorimetric test for total flavonoid content, phosphomolybdate assay for antioxidant activity analysis, and Fourier transform infrared spectroscopy (FT-IR) for determining various functional groups present in these phytochemicals. Phytochemical contents, antioxidant activities and functional groups are compared in different types of leaves as well as different solvents. The results of the study revealed that shade-dried leaves extracted using distilled water and fresh leaves extracted using methanol have high TAA which is 0.371 ± 0.02 µg/mL and 0.375 ± 0.01 µg/mL, respectively. This high antioxidant activity is due to high phenolic and flavonoid content in these samples, 67.03±3.10, 0.75±0.13 (mg GAE/g dry weight) for M. koenigii Shade Dried Water extract (MKShDW) and 112.94±1.03, 0.52±0.08 (mg QE/g Fresh Weight) for M. koenigii Fresh Methanolic extract (MKFrMe), respectively. Thus, these leaves can be used as a good source of natural antioxidants. Various functional groups are observed in the FT-IR analysis of this study such as alkanes, alcohols/phenols, aldehydes, esters, ethers, amines, amides, etc.
Evaluation of Pakistani Medicinal Plants used traditionally to treat Leishmaniasis
Authors: Shah Syed Majid
Published: December 2024

Cutaneous leishmaniasis (CL) is caused by various species of the protozoal parasite Leishmania, affectingapproximately ten million individuals globally [1] CL, which is mostly caused by Leishmania tropica, is most prevalentin Pakistan and is expanding throughout the country as a result of the migration of several million people. About ninetypercent cases of CL have been reported from all the provinces of Pakistan. Pentavalent antimonial is the standardtreatment, but these drugs are very expensive and has many adverse effects when used parenterally. Existingchemotherapies can be replaced by the reasonable research for new anti-leishmanial drugs. A literature reviewdisplayed that no natural compound has been approved against leishmaniasis.Medicinal plants which are using traditionally for Leishmania were collected from different areas of Pakistan. TheMethanolic extracts and derived fractions were formed following standard extraction and fractionation thecniques. Allthe crude extracts were tested for the presence of important secondary metabolites. All extracts were evaluated for antileishmanial activity using Leishmania tropica promastigotes.The extracts of three medicinal plants Citrulluscolocynthis (L.) chrad (IC50 12.25 µg/mL), Juniperus M. Bieb (IC50 11.97 µg/mL) and Asparagus gracilis L (IC50 10.68)(µg/mL) show significant activity and thus recommended for further isolation of compounds. Bioassay-guidedfractionation and isolation will be carried out according to standard extraction and chromatographic techniques. Finally,the preliminary and mechanistic antileishmanial studies of pure compounds will be conducted to discover costeffective and safe drugs to public suffering from CL in Pakistan and across the globe.
Evaluation of in-vitro cytotoxicity and in-vivo toxicity of aqueous fraction of Ribes orientale aqueous ethanolic extract using rodents
Authors: Uttrra Dr. Ambreen Malik
Published: December 2024

The present research investigated the probability of toxicity of the aqueous fraction of Ribes orientale (ROAF) after acute, subacute, and sub-chronic periods of administration. Mice were given doses varying between 10–5000 mg/kg during the acute trial. Rats were administered 50, 100, and 200 mg/kg doses for 30 days, whereas 300, 600, and 900 mg/kg doses were given for 14 days. The rats' weight as a whole, organ weight, hematology and biochemical indices, and histology of liver, kidney, and heart tissue had all been assessed. Because no dose incited notable behavioral alterations or mortality in an acute poisoning, the LD50 was higher than 5000 mg/kg. For sub-acute toxicities, ROAF had no effect on body or organ weight, while only slight changes of both serum and blood measurements were identified. But just slight changes in lymphocytes and neutrophils, total protein, ALP and glucose at some doses were noted but these changes were not allied with histopathological alterations. In sub-chronic toxicity, ROAF did not modify weights (body/organ), non-significant variances in hematology and biochemistry were observed, affirmed by histopathology. Therefore, the results above indicate that ROAF is rather safe to take orally with a broad margin of safety for therapeutic usage at lower dosages because it did not cause death in animals or create any notable side effects related to hematological, biochemical, or structural processes.
ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF HERTIA INTERMEDIA LEAF EXTRACT IN RATS
Authors: Arif Mehreen
Published: December 2024

Background: Hertia plants have been used in traditional societies to treat pain but to scientifically prove the analgesic effects of this plant, no comprehensive research has been done previously. Objective: The purpose of this study was to investigate the potential mechanism of action and analgesic and anti-inflammatory properties of Hertia intermedia leaf extract. Methodology: In this investigation, rats were given several doses of Hertia intermedia extract, and its analgesic effects were assessed using the tail-flick, hot plate, and formalin tests. Rats were pre-treated with naloxone to have a look at the potential mechanism. The levels of inflammatory factors TNF-α and IL-6 in the blood of rats were assessed. To gain insight into the active substances, phytochemical tests were carried out. Results: The study's findings demonstrated the potential of Hertia intermedia leaf extract to alleviate pain and inflammation at various doses. It is possible that the extract functions through opioid receptors because naloxone administrations also dramatically decreased the latency in response to pain in the hot plate and tail flick tests. When measured against the control group, the 150 mg/kg dose significantly reduced the levels of TNF-α and IL-6 cytokines. Conclusion: According to the study's findings, Hertia intermedia leaf extract mitigates inflammatory cytokines and has analgesic effects on both the central and peripheral nervous systems.
Inkarrí: ¿Trilce o poemas humanos?
Authors: Granados Agüero Pedro
Published: December 2024

En el presente artículo, analizamos “Terrremoto” (1937), póstumo texto de Poemas humanos, con tan elocuente vocablo, en relación con el mito de Inkarrí (“cambio radical o pachacuti”). Asimismo, lo cotejamos con el análisis del poema XLVII de Trilce (1922), “Ciliado arrecife donde nací” (Granados, 2014), ya que, además de su especificidad cultural, grosso modo, ambos poemas tratan de la asunción del ser femenino o materno y, de modo simultáneo, también del aborto. Ahora, ¿por qué aquella disyuntiva entre Trilce o Poemas humanos? Porque deseamos abundar en el debate, para nada cancelado, de si Trilce es “mejor” que los poemas póstumos, o viceversa; obviamente, tal asignación de valor se daría en términos de una específica y productiva respuesta a una coordenada local/ global. Perspectiva de estudio, la nuestra, análoga a la diglosia “Paris/ París” que percibiera Enrique Ballón en la poesía de César Vallejo (Ballón Aguirre, 2015), una vez que este ya residiera en Europa; y enfoque por el cual nos preguntamos cómo o hasta qué punto podríamos hablar, para el caso de la poesía del autor peruano, de una “desposesión y lenguaje en el exilio” (Niebylski, 2002). Concluimos que, respecto a la más lograda “encarnación” de Inkarrí en su poesía, Vallejo optaría por Trilce y que, asimismo, jamás hubiera reunido ni publicado en vida el conjunto de su poesía europea bajo el lema de Poemas humanos; y sí, muy probablemente, bajo el título de Poemas multinaturalistas (Viveiros de Castro, 2010) o Poemas poshumanos.
Malinche, de Hilde Krüger: hacia una quiebra del mito fundacional en el México de los años cuarenta
Authors: Aracil Beatriz
Published: December 2024

El presente trabajo aborda un breve ensayo de la actriz y escritora alemana Hilde Krüger titulado Malinche o El Adiós a los Mitos (1944). En una época en la que el mito de la Malinche traidora convive con una reivindicación del papel histórico de la traductora de Cortés, Krüger, al igual que otras escritoras contemporáneas, defiende abiertamente a su protagonista, pero además reinterpreta el término “Malinche” recuperando el sentido que los indígenas dieron al mismo en el siglo XVI. Para nuestra autora, Marina y Cortés conforman un ser mítico, “Malinche”, que anuncia a los aztecas el fin de su mundo.
A Representative DNA Sequence Analysis with High-Throughput Whole Genome Resequencing Data
Authors: Kansu Çiğdem , Holliday Jason A.
Published: December 2024

Rapid advances in DNA sequencing technologies made it cost-effective to get high-throughput genomic sequence data. Applications in whole genome resequencing presented new approaches to investigate natural variation and adaptation of species. The genus Populus in the Salicaceae family includes economically and ecologically critical species that are dioecious, wind-pollinated, and predominantly distributed in river ecosystems. Poplar serves as a model for the research on the evolutionary genomics of forest tree species. In this study, we aimed to present an example of a comprehensive SNP calling pipeline, demonstrating its application in elucidating genetic diversity and population structure from whole genome resequencing data. The results discovered genetic variants from whole genome resequencing data of poplar species. The pipeline involved sequence preprocessing, alignment to the reference genome, and variant calling.
Preparation and Dual-Functionalization of Pendant Aldehyde and Azide-Bearing Hydrophilic Polymer
Authors: Cengiz Nergiz
Published: December 2024

Polymers with more than one functionality hold significant value due to their diverse applications across various biological fields. This study describes the synthesis of dual-reactive and hydrophilic polymer via Reversible Addition-Fragmentation Chain Transfer Polymerization (RAFT), suitable for drug delivery systems. Pendant hydrophilic polyethylene glycol units enhance the polymer's water solubility, while aldehyde and azide side chains create opportunities for further functionalization. Side chain functionalization studies were conducted using amine and alkyne-containing model molecules. Azide side chains were functionalized with ((prop-2-yn-1-yloxy)methyl)benzene through the Huisgen-Click reaction while the aldehyde side chains were linked to amyl amine via reductive amination reaction.
Cartilha educativa para promoção do autocuidado bucal: percepção de pacientes idosos usuários de próteses dentárias removíveis
Authors: Dantas Leonardo Pereira , Caldas Germana Freire Rocha , Malta Yngrid Galdino Dantas , Teixeira Marlene Menezes de Souza , Silva João Marcos Ferreira de Lima , Trigueiro Emília Suitberta de Oliveira
Published: December 2024

Este estudo teve como objetivo analisar a percepção de pacientes da terceira idade usuários de próteses dentárias removíveis atendidos em um Centro de Especialidades Odontológicas, quanto a relevância da utilização de uma cartilha intitulada “Próteses Dentárias Removíveis - Cartilha Educativa para Autocuidado na Terceira Idade” como ferramenta didática para o autocuidado no contexto da saúde bucal. Participaram da pesquisa 23 idosos, com idade compreendida entre 60 e 80 anos, funcionalmente independentes. A avaliação da aceitação da cartilha foi realizada em consultório, de forma individual concomitante às suas consultas por meio de questionário semiestruturado. A pesquisa foi aprovada pelo Comitê de Ética em Pesquisas do Centro Universitário Dr. Leão Sampaio, sob Parecer nº 3.643.127. Os participantes em sua maioria são mulheres, de com ensino fundamental completo e aposentados e faixa etária predominante entre 60 e 65 anos. A maioria dos pacientes relatou ser afetada pela ausência dos dentes em seu convívio e relacionamento com outras pessoas. Quanto aos cuidados com a prótese 48% afirmaram não fazer a remoção da prótese para dormir e os que as faziam não sabiam qual recipiente acondicioná-las e/ou substância higienizá-las acondicionar. Nesse sentido, tais informações ressaltam a necessidade de uma abordagem instrucional que induza os pacientes a uma padronização destas práticas e medidas. O estudo mostrou que o estímulo ao autocuidado bucal pode ser estimulado através de uma cartilha educativa. Esse recurso didático pode ainda impactar positivamente na comunidade dada a disseminação das medidas aprendidas.
Kumpulan data citra telepon pintar untuk identifikasi varietas cabai merah berbasis daun
Authors: Suwarningsih Wiwin , Evandri Evandri , Kirana Rinda , Purnomo Husnul Khotimah  , Dianadewi Riswantini  , Ekasari Nugraheni  , Andri Fachrur Rozie  , Andria Arisal  , Devi Munandar  , Noor Roufiq Ahmadi
Published: December 2024

Chili plants played an important role in human life, serving as a source of income for farmers, as a provider of employment, and as a source of vitamins and minerals for the community. Market demand for red chili continued to increase, encouraging seed producers to provide quality plant seeds. The requirements for selecting plant varieties were based on market demand (taste, color, appearance, size, etc.), high productivity, resistance to plant pest attacks, and suitability for planting in local ecosystem conditions. Based on this, a smart approach was needed to identify plant varieties to maintain seed purity. To facilitate and streamline leaf-based chili variety identification, a comprehensive dataset was compiled. This dataset, consisting of 3877 leaf images divided into 12 variety classes, aimed to determine which plants were parent seeds or seeds that had deviations from their varieties. Leaf images were collected from the BALITSA garden through observations of leaf growth from shoots to 20 days of plant age. Various strict steps were taken to ensure the quality of the dataset and increase its usefulness. Chili leaf images taken from various angles and having high resolution were designed to assist in the development of highly accurate models. By leveraging this curated dataset, it was possible to train a model for real-time leaf-based identification of chili varieties, which significantly helped in the timely identification of such conditions.
FACIES ANALYSIS AND SEDIMENTATION MECHANISM OF VOLCANICLASTICS OF CIKARANG MEMBER OF JAMPANG FORMATION IN WEST JAVA
Authors: Anhaer Naufal , Novian Moch. Indra , Novita Dian
Published: December 2024

The Cikarang Member of Jampang Formation is one of basin fills of the Bogor Basin that is characterized by gravity flow deposits. The variations of lithologies with an abundance of volcaniclastics are found in the Tonjong River in Bojongkalong Village and indicate differences in facies and sedimentation mechanisms. We measured stratigraphy of the rock units supported by petrographic analysis and paleontological analysis. The rock units consist of 11 lithofacies: graded gravel (g1G), massive gravel (m1G), massive gravelly sand (mGyS), plane-stratified laminated sand-mud couplets (slSM), massive gravel-sand couplets (mGS), plane-stratified laminated to graded mud-sand couplets (slgMS), massive sand (mS), plane-stratified gravel-sand couplets (sGS), plane-stratified laminated muddy interval sand-mud couplets (sleSM), plane-stratified laminated muddy interval mud-sand couplets (sleMS), and slump and slide deposits gravel (sdG). The depositional environment of the Cikarang Member is inner-middle fan with changes in depositional sub-environment variations in the form of channels, sandy lobes, silty-sandy distal lobes, and proximal levees with constant paleobathymetry in the lower-middle bathymetry. The volcaniclastics of the Cikarang Member of Jampang Formation is deposited in a turbid mechanism due to a turbulent current with various cohesive debris flows (mudflows) and turbidity currents scattered in each facies association.
Methanol cells
Authors: Garwol Arkadiusz
Published: December 2024

This article provides an overview of the types of fuel cells currently in use, taking into account their properties, which are related to devices that operate similarly to fuel cells, such as batteries. In addition, some of the exemplary development trends of methanol fuel cells are identified, such as development work carried out on the implementation of electrodes made of new types of materials. A description of the method of obtaining energy from methanol is also included, and current applications of methanol cells are described using the example of a submarine structure and a forklift.
AVIATION NOISE - PROBLEM SPECIFICATION
Authors: Witoś Mirosław , Wachłaczenko Michał , Wajda-Figur Honorata , Kozieł Mariusz
Published: December 2024

The dynamic growth of air transport is a source of aviation noise, especially felt by people near major airports located near metropolitan areas of thousands of people. The article presents the authors' holistic view of the problem of aviation noise, pointing out direct and indirect sources of noise emissions, social and legal conditions and sample research results. First, the research problem is introduced. This is followed by an analysis of the legal status and the ICAO approach to aircraft noise management. The topic discussed was illustrated with examples. Finally, the authors' observations from the conducted research are indicated.
NGHIÊN CỨU XÂY DỰNG QUY TRÌNH XÁC ĐỊNH HIỆU GIÁ HUYẾT THANH KHÁNG DẠI BẰNG PHƯƠNG PHÁP TRUNG HÒA TRÊN TẾ BÀO BHK21
Authors: Nguyễn Thị Mai Hương  , Vũ Thị Thu Hường  , Nguyễn Thị Tường An  , Phạm Thị Hồng Thủy  , Cao Thị Vân  , Nguyễn Kim Hùng
Published: December 2024

Hiện nay, Viện Kiểm định Quốc gia Vắc xin và Sinh phẩm y tế (NICVB) đang thực hiện thử nghiệm xác định hiệu giá huyết thanh kháng dại bằng phương pháp trung hòa kháng thể trên chuột nhắt trắng  (MNT), tuy nhiên phương pháp này còn có nhiều hạn chế. Từ năm 2018, phương pháp xác định hiệu giá kháng thể trung hòa trên tế bào BHK 21 (FAVN) được Tổ chức Y tế thế giới (WHO) khuyến cáo áp dụng thay thế cho phương pháp MNT. Do đó, nghiên cứu này được tiến hành nhằm xây dựng quy trình xác định hiệu giá kháng huyết thanh dại trên sinh phẩm sản xuất từ huyết thanh ngựa bằng phương pháp trung hòa trên tế bào BHK 21 và thẩm định một phần quy trình dựa trên các tiêu chí độ đúng, độ lặp lại và độ chính xác trung gian. Đề tài đã xây dựng quy trình với nồng độ tế bào tối ưu đưa vào thử nghiệm là 5 x105 tế bào/ml. Quy trình thực hiện đảm bảo độ tin cậy với tính đúng của hiệu giá trung bình mẫu chuẩn kháng dại quốc tế mã NIBSC 19/244 là 167,52IU, có độ thu hồi R% là 102,14% so với giá trị hiệu giá của mẫu chuẩn đã công bố. Hệ số biến thiên (CV) trên các tiêu chí độ lặp lại và độ chính xác trung gian nhỏ hơn 20%, hoàn toàn phù hợp cho áp dụng thực tiễn trong công tác kiểm định huyết thanh kháng dại tại NICVB
TỔNG HỢP VÀ CHUYỂN HOÁ MỘT SỐ HỢP CHẤT 4,6-ARYLPYRIMIDINE-2(1H)-THIONE CÓ CHỨA NHÓM PROPARGYL
Authors: Bùi Thanh Tùng  , Nguyễn Đình Thành  , Nguyễn Thị Thu Trang
Published: December 2024

Việc tổng hợp các chất dị vòng chứa nitrogen đang nhận được rất nhiều sự quan tâm của các nhà tổng hợp hữu cơ do hoạt tính sinh học đa dạng của chúng. Hợp chất dị vòng có mặt trong cấu trúc của nhiều hợp chất thiên nhiên và có vai trò quan trọng trong cuộc sống. Trong bài báo này, chúng tôi thực hiện phản ứng click để tổng hợp một số hợp chất có chứa đồng thời dị vòng pyrimidine và 1,2,3-triazole gắn với vòng đường D-glucose. Các hợp chất kiểu này được dự đoán có thể có các hoạt tính sinh học mang lại từ 2 dị vòng, và có thể được thử nghiệm hay ứng dụng trong nghiên cứu sản xuất thuốc.
NGHIÊN CỨU ỨNG DỤNG TRÍ TUỆ NHÂN TẠO TRONG LẬP CÔNG THỨC NHIỄM SẮC THỂ Ở NGƯỜI
Authors: Đoàn Thị Kim Phượng  , Vũ Hồng Bảo Nguyên  , Lương Thị Lan Anh  , Lưu Mạnh Hà
Published: December 2024

Mục tiêu: Đánh giá hiệu quả của phần mềm trí tuệ nhân tạo trong lập công thức nhiễm sắc thể (NST) ở người. Phương pháp nghiên cứu: Mô tả cắt ngang. Kết quả: Nghiên cứu trên 237 hình ảnh cụm NST tương ứng với 10841 hình ảnh NST đơn lẻ kì giữa nhuộm băng Giemsa của các bệnh nhân làm xét nghiệm NST đồ từ máu ngoại vi tại Trung tâm Di truyền lâm sàng- Bệnh viện Đại học Y Hà Nội từ tháng 6/2023 đến tháng 8/2024 trong đánh giá hiệu quả phân loại và phân cực NST tự động của phần mềm trí tuệ nhân tạo cho thấy, độ chính xác phân loại NST là 95,9%, độ chính xác phân loại NST trung bình trên một cụm NST là 95,9 ± 4,1%. F1-score, Recall và Precision phân loại NST lần lượt là 94,59%, 93,85% và 96,16%. Độ chính xác phân cực NST là 98,7%, độ chính xác phân cực NST trung bình trên một cụm NST là 98,74 ± 1,99%. Kết luận: Phần mềm trí tuệ trong nghiên cứu có mô hình phân loại và phân cực NST tốt, có thể ứng dụng hỗ trợ làm giảm công sức cho người thực hiện xét nghiệm NST đồ
القسم ودلالاته في القرآن الكريم: دراسة موضوعية تحليلية
Authors: Aydın Süleyman
Published: December 2024

عالجت في هذا البحث موضوعا هاما من مباحث أصول التفسير وعلوم القرآن موضوع القسم في القرآن المجيد وهو ثاني أسلوب من أساليب الإقناع. وبينت فيه المعاني المرادة الحقيقية أو المجازية والفوارق اللغوية والاصطلاحية والأسرار والحكم لكلمة قسم و أقسام ومترادفاتها ، وتحدثت فيه عن ماهية القسم وأقسامه وأنواعه ودلالاته في صورة قواعد بتحقيقات مبثوثة في كتب من سبقنا وبما فتح الله علينا. وهذا البحث من البحوث التي تقوم على دراسة مفردة من مفردات القرآن الحكيم وموضوع من موضوعاته كالأمثال والجدل بمنهجية التفسير الموضوعي والتحليلي معا. وبينت فيه بعض الحقائق الهامة منها أن القسم من الأساليب العربية التي تظهر إعجاز القرآن وتؤكد الأمر وتظهر أهميته والعناية به,وأنه يمكن أن يعتبر من باب تصريف الخطاب وتلوينه: {وَكَذَٰلِكَ أَنزَلْنَاهُ قُرْآنًا عَرَبِيًّا وَصَرَّفْنَا فِيهِ مِنَ الْوَعِيدِ لَعَلَّهُمْ يَتَّقُونَ أَوْ يُحْدِثُ لَهُمْ ذِكْرًا} [طه:113].وأن موضوع القسم يظهر لنا أنواعا شتى من المناسبات القرآنية.
EVALUASI AUDIT SYARIAH: ANALISIS KEPATUHAN LEMBAGA KEUANGAN SYARIAH TERHADAP PRINSIP-PRINSIP ISLAM MELALUI KAJIAN LITERATUR DAN CHECKLIST IMPLEMENTASI
Authors: Nugroho Tulus Pujo
Published: December 2024

Audit syariah memainkan peran penting dalam memastikan kepatuhan lembaga keuangan syariah terhadap prinsip-prinsip Islam. Studi ini bertujuan untuk meninjau literatur mengenai audit syariah, dengan fokus pada ruang lingkup, tantangan, kompetensi auditor, dan dampak terhadap tata kelola lembaga keuangan syariah. Berdasarkan hasil analisis, audit syariah memiliki cakupan yang lebih luas dibandingkan audit konvensional, mencakup aspek moral, etika, dan spiritual selain aspek keuangan. Penelitian juga menunjukkan bahwa banyak auditor syariah belum memiliki kompetensi yang memadai, sehingga pendidikan, pelatihan, dan sertifikasi menjadi kebutuhan mendesak. Standar audit internasional, seperti yang dikembangkan oleh AAOIFI, memberikan kerangka kerja yang relevan, tetapi implementasinya masih menghadapi berbagai tantangan. Ketidakpatuhan terhadap syariah dapat merusak reputasi lembaga keuangan dan mengurangi kepercayaan masyarakat, menjadikannya tantangan utama bagi sektor ini. Temuan ini menegaskan perlunya kolaborasi antara pemerintah, industri, dan akademisi untuk memperkuat tata kelola dan audit syariah. Dengan meningkatkan kompetensi auditor dan memperkuat kerangka kerja audit, audit syariah dapat berkontribusi signifikan dalam menjaga kepercayaan publik dan keberlanjutan sektor keuangan syariah.
Senolytics and Their Effects on Various Diseases
Authors: Danış Oruç Kübra , Mutlu Ayşe Gül
Published: December 2024

Senescence is the result of a process that is physiological for cells. With aging, there is an increase in the number of senescent cells in organisms, and these cells produce a number of compounds known as senescence-associated secretory phenotype (SASP). These compounds secreted by senescent cells cause healthy cells in the microenvironment to exposure senescence. Therefore, preventing the accumulation of senescent cells in tissues is important for healthy cells. Senolytics are compounds that can specifically eliminate senescent cells. One of the most important differences between a cell in its normal physiological process and a senescent cell is that senescent cells are resistant to apoptosis. Although senolytics have different mechanisms of action, they jointly target the anti-apoptotic pathways of the cells and the compounds in these pathways, thereby enabling the senescent cells to undergo apoptosis and be destroyed. In addition, accumulation of senescent cells in tissues increases the risk of susceptibility to various chronic diseases, especially cardiovascular diseases, neurodegenerative diseases, cancer and kidney diseases. Therefore, it is forecasted that inhibiting the accumulation of senescent cells in tissues may reduce the risk of disease. In this review study, the effects of senolytic compound examples such as Dasatinib, Quercetin, Navitoxlac (ABT-263) and Fisetin on cardiovascular diseases, neurodegenerative diseases, cancer, kidney diseases and inflammation were briefly summarized.
Examining the Food Label Reading Habits and Attitudes Towards Healthy Nutrition Among Healthcare Professionals: A Cross-Sectional Study
Authors: Kemaloglu Mehmetcan , Kemaloğlu Emine
Published: December 2024

Aim: This study was conducted to evaluate the food label reading habits of healthcare professionals and their attitudes towards healthy nutrition.
Material and methods: 198 healthcare professional were included in the study. Data regarding individuals' demographic characteristics, attitudes towards healthy eating (ASHN) and food label reading habits were obtained via an online form.
Results: When the data obtained is examined, the average age of the group is 27.5; It was determined that the average BMI was 23.6 kg/m2. It was determined that the general average of the individuals' ASHN total score was 73.15±10.18 and therefore the group's general attitude towards healthy nutrition was high. When the nutrition food label reading status and ASHN scores were compared, it was determined that the attitude scores towards healthy nutrition of individuals who responded often and always to the habit of reading food labels were higher than those who responded never, rarely or sometimes. It was also found that individuals who had previously received nutrition education had higher ASHN scores compared to those who had not received nutrition education.
Conclusion: As a result of the study, it was determined that there was a weak positive relationship between food label reading habits of healthcare professionals and ASHN scores.
Incidence of Brackishness in Ground Water from Bore Wells Drilled in Deeper Aquifers in Parts of Kozhikode District, Kerala, Southern India
Authors:   Central Ground Water Board, SWR, Bengaluru-560102(KN), India, K Anisha , V.S. Joji ,   Department of Marine Geology and Geophysics, Cochin University of Science and Technology, Kochi-682022(KL), India, V.K. Vijesh ,   Central Ground Water Board, CHQ, Faridabad-121001(HR), India, T.S. Anitha Shyam ,   Central Ground Water Board, CHQ, Faridabad-121001(HR), India
Published: December 2024

Seasonal salinity along river mouths is generally observed in the coastal tracts of Kerala at places. The problem is felt during summer season with the incursion of sea water along river mouths, which imparts brackishness to the adjoining phreatic aquifer systems along the coastal tracts of Kerala. This process is reversible through seasons; during the rainy season, the aquifer freshens up and by summer it becomes brackish. However, the reports of brackish water in bore wells tapping deeper crystalline formations are quite rare in Kerala. This paper discusses the comparison of hydrochemical characteristics of bore wells tapping freshwater to those of having relatively high TDS. Major hydrochemistry of the water samples was studied and in Hill Piper diagram 88% of the samples fall in the field of Ca2+˗ HCO– type facies. The ionic abundance can be expressed as Ca2+>Mg+>Na2+ for cations and for the anions as HCO– >Cl– >SO2– and the EC values range from 82-292μS/cm. The remaining 12 percentage of the samples are found to have relatively high TDS and falls in the field of Na+˗Ca+˗Cl– type and the brackishness of the bore well water could be partly attributed to the inflow of saline water to the deep fractured aquifer systems through lineaments connected to brackish surface water body/sea. Besides, the phreatic aquifers in the area are copiously fresh and EC values are generally below 500μS/cm. Out of the three wells with brackishness, EC values of two wells were found to above 10000μS/cm (Ramanattukara and Kannore) whereas at Paleriitis 1765μS/cm. It is revealed that majority (88%) of the ground water samples are highly suitable for agricultural purposes with all types of soil except those of the Ramanattukara, Kannore and at Paleri exploratory bore well samples.

Keywords: Litholog, Hydrogeology, Hydrochemistry, Mixing, Deeper Aquifer, Kozhikode
Spooneromyces velenovskyi (Vacek ex Svrček) van Vooren, første funn i Norge
Authors: Kristiansen Roy
Published: December 2024

Discomyceten Spooneromyces velenovskyi (Vacek) van Vooren beskrives fra Øvre Forra naturreservat i Levanger kommune, Nord-Trøndelag. Soppen opptrer som 1-5 mm store apothecier sammen med Spooneromyces laeticolor (P. Karst.) T. Schumach. & J. Moravec. Dette er første funn av arten i Norge.
SAÚDE, SAÚDE FINANCEIRA, ECONOMIA E INTERESSES: A PAUTA DOS DIREITOS HUMANOS FORA DA PAUTA DAS BETS
Authors: Malonn Cristiane Martins , Rudnicki Dani
Published: December 2024

Fixed-odds betting in Brazil was regulated on December 29, 2023, more than 04 (four) years after its legislative conception. The economic agenda is a fact, if the legislation on the subject is observed. However, the human factor does not appear with the same clarity, questioning the observance of Human Rights. This article addresses the interaction between the betting market, economic interests, the physical and financial health of bettors and the Rights that are at stake, even before the start of the operation of the regulated market. Exploratory and explanatory methodology was used, with a qualitative approach and a technical approach to bibliographic research, with critical interpretation of the data. The themes of fixed-odds betting, also called online betting, and the focus on the integrality of the person, now bettor, are highlighted. The betting market has gained visibility in recent years and needs to be faced from the perspective of Human Rights.
EDUCAÇÃO, TECNOLOGIA E SUSTENTABILIDADE: FORMANDO CIDADÃOS GLOBAIS
Authors: Demuner Jocelino Antonio , Dariva Roselia Negri , Antunes Edmilson Jovino , Da Silva Ricardo Toledo , Carvalho Elizangela Alves
Published: December 2024

This article investigated the intersections between education, technology, and sustainability in the context of digital transformation, with the aim of analyzing how emerging technologies can promote inclusive and socially responsible educational practices. The research addressed topics such as digitalization in the education sector, the integration of the Internet of Things, big data analysis,  and the use of augmented reality, highlighting their implications for the formation of conscious and sustainable global citizens. To answer the central question of the study, a bibliographic research was carried out, following the theoretical approach described by Gil (2002), who considers this methodology adequate to organize and systematize dispersed information, and by Marconi and Lakatos (2003), who highlighted its importance in the construction of a consistent theoretical framework. The data analysis revealed that the digital transformation has democratized access to educational tools, expanding learning opportunities for marginalized populations and promoting greater efficiency in pedagogical and administrative processes. However, the results also pointed out limitations, such as the difficulty of technological implementation in regions with low infrastructure and the need for ethical governance to avoid inequalities. It was concluded that the integration of emerging technologies with educational practices can be an effective strategy to face global challenges, such as inclusion, sustainability and equity, as long as it is accompanied by public policies that guarantee universal access to technological innovations. Thus, this study contributed to the debate on education and technology as pillars for a sustainable future, encouraging new research on the subject.