bluuebunny/crossref_metadata_2025 huggingface dataset:
The View of the Experts on the Currency Depreciation of Cash Waqf Value
Authors: Amalia Rahmi
Published: January 2021

This study aims to analyze the view of the experts on the currency depreciation of cash waqf value. This research was decriptive qualitatif, the method of collecting data done by documentation and an interview. The data analysis used was content analysis. The result of this study found that the experts all agreed that the risk of decreasing currency value will have an impact on the value of cash waqf.
Stylistic Analysis in Surah Al-Najm
Authors: Walidah Ziana , Yanuar Muslim , Azizah Dyah Nurul , Qalyubi Syihabuddin
Published: January 2021

Stylistic is a multidisciplinary approach that aims to foreground the peculiar properties of texts on the basis of language and derive hidden and in-depth meaning to figure out major and minor themes. The evident fact that makes Stylistic a multidisciplinary approach is its retrievable, rigorous, and replicable principles. With Stylistic science, someone can reveal the secrets of the Qur’an as a whole by analyzing all aspects of the Qur’anic linguistics. This article aimed to analyze Surah al-Najm with the Stylistic theory. The research was qualitative research with library research or literature study. The analysis was carried out using an objective approach and descriptive analysis method by reading Surah al-Najm repeatedly then collecting relevant data. So, the data that has been found was analyzed with the two terms of Stylistics, they are semantics and imagery. From this study, it was concluded that in Surah al-Najm there were (1) nouns and verb preferences, various sentence structures and sentence confirmation in syntactic aspects, synonyms and antonyms in semantic aspects, and (2) several kinds of language styles such as isti'arah, majaz, and kinayah in imagery.
The Influence of Using Audio-lingual Method on Students’ Speaking Skill in Madrasah Diniyah Takmiliyah Awwaliyyah
Authors: Aprianto Aprianto , Ritonga Mahyudin , Marlius Yoni , Nusyur Raihan
Published: January 2021

The study aimed to determine the influence of audio-lingual methods towards the Arabic speaking skills, the method used in this research was quantitative with experimental quasi approach, data collection technique was polling and test. The population of this research was 102 students in the MDTA Bustanul Huda at Padang City, West Sumatera, Indonesia. Data obtained through polls and tests were then analyzed statistically. The analysis used the normality test, homogeneity test, and hypothesis test. All three types of tests were done with the help of the SPSS Statistics 22 program. The results of the study were: 1) the use of audio-lingual methods was categorized on good classification with an average of 63.33 in intervals 62-64; 2) Speaking Arabic skills was categorized on good classification with an average of 68 in intervals 65-68; and 3) the score of influence with N 30 obtained sig α 0.001 and the score of r Square 0.35. There was a significant influence between the use of audio-lingual methods to the Arabic speaking skill of students at MDTA Bustanul Huda Ulak Karang at Padang City Indonesia in the academic year 2019/2020. The influence of variable X to variable Y because students are accustomed to hearing how to speak Arabic as the native speaker of the Arabic language.
Penerapan Media Game Ular Tangga Digital untuk Meningkatkan Hasil Belajar Tematik
Authors: Novita Lina , Sundari Fitri Siti , Rabani Khansa Rohadatul’Aisy
Published: January 2021

Kurikulum 2013 lebih menekankan keaktifan peserta didik, namun penerapan pembelajaran masih berpusat pada guru. Salah satu penyebab adalah kurangnya penggunaan media pembelajaran. Oleh sebab itu perlu dilakukan upaya dalam meningkatkan kualitas pembelajaran.  Penelitian ini bertujuan untuk meningkatkan hasil belajar dan menumbuhkan keaktifan siswa dengan penggunaan media ular tangga digital. Metode penelitian tindakan kelas digunakan dalam penelitian ini. Subjek penelitian siswa kelas IV berjumlah 35 siswa. Penelitian ini dilakukan dengan 2 siklus, yang terdiri dari perencanaan, pelaksanaan, pengamatan, dan refleksi. Siklus 2 dilakukan, apabila pada siklus 1 belum mencapai indikator keberhasilan pembelajaran. Pengumpulan data dan analisis data dilakukan dari hasil pelaksanaan pembelajaran dan observasi yang dilakukan kolaborator. Hasil penelitian menunjukkan adanya peningkatan hasil belajar dan perubahan sikap dengan penggunaan media game ular tangga digital. Peningkatan tersebut dibuktikan dengan angka rata-rata siklus 1, yaitu 74,42 meningkat menjadi 84,02 pada siklus 2, artinya terjadi peningkatan 9,6. Dengan demikian dapat disimpulkan bahwa media ular tangga digital dapat meningkatkan hasil belajar dan adanya perubahan aktivitas siswa pada proses pembelajaran. Hal ini dapat dikatakan bahwa pembelajaran dengan menggunakan media baik itu ular tangga digital maupun media pembelajaran lainnya dapat mengubah pembelajaran menjadi lebih aktif
Visualisasi dan Makna Filosofi Motif Batik Teratai di Galeri Soendari Berbasis Penguatan Pendidikan Karakter
Authors: Wijayaningputri Arinta Rezty
Published: January 2021

Tujuan penelitian ini untuk (1) Mendeskripsikan Visualisasi Motif Batik Teratai di Galeri Soendari Berbasis Penguatan Pendidikan Karakter, (2) Mendeskripsikan Makna Filosofi Motif Batik Teratai di Galeri Soendari Berbasis Penguatan Pendidikan Karakter, (3) Menganalisis muatan karakter pada Motif Batik Teratai. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian deskriptif. Subjek dalam penelitian ini yaitu motif batik Malangan. Hasil penelitian yang diperoleh adalah (1) Di dalam Motif Batik Teratai terdapat beberapa visual atau bentuk motif diantaranya motif bunga teratai, sulur-sulur dan daun dari bunga teratai. (2) Beberapa motif dari Batik Teratai memeiliki makna filosofi yaitu untuk motif bunga teratai selain melambangkan keindahan juga memiliki makna kesuburan dimana diharapkan pemakainya senantiasa subur makmur dan terpelihara jiwa dan raganya, sedangkan untuk sulur-sulur merupakan simbol bahwa perwujudan suatu kehidupan itu akan terus berlangsung, tumbuh dan berkembang tapi tak abadi dan senantiasa mengingatkan bahwa manusia pasti akan mati dan makna filosofi daun dari bunga teratai adalah mengajarkan tentang kehidupan kaya yang harus disyukuri dan dijaga. (3) Muatan nilai karakter yang bisa diambil dari Motif Bunga Teratai dapat dilihat dan dianalisis antara lain dari (bentuk/visual) maupun warna yang ada dalam batik teratai
Environmental literacy-based on adiwiyata predicate at junior high school in Ponorogo
Authors: Waqidah Siti Nur , Suciati S. , Ramli Murni
Published: January 2021

The student's environmental literacy (EL) is vital to improving students' awareness of environmental issues. This study was intended to display the role of eco-school program (Adiwiyata) and non-adiwiyata schools towards EL of junior high school students by analyzing EL of students in Ponorogo. The research was conducted in March-October. The survey involved 379 students. The type of research is ex post facto. The assessment used the Middle School Environmental Literacy Survey (MSELS). The results show that the adiwiyata program is related to the increase of EL with the sig value. 0.000. The higher the adiwiyata level, the higher the EL value of the environment. However, the general EL assessment in Ponorogo is still low, that more than 51% of respondents did not reach the score at level 3, which is the standard level of EL. The EL ability of junior high school students between male and female sex is different, with the sig value. 0.004. All data analysis concluded that the level of students' EL was significantly influenced by school type and gender. EL of students may low due to students' lack of understanding of the environment concepts, the limited theories, and concepts transferred to students.
Analisis Epistemological Obstacle Siswa Dalam Menyelesaikan Soal Cerita Matematika Berdasarkan Gaya Kognitif
Authors: Siswanto Rizki Dwi
Published: January 2021

Penelitian ini bertujuan untuk mengetahui penyebab dan mendeskripsikan epistemological obstacle yang terjadi pada siswa dalam menyelesaikan soal cerita operasi hitung pecahan matematika berdasarkan gaya kognitif pada siswa kelas V SD Negeri Pademangan Barat 11 Jakarta Utara tahun ajaran 2018/2019. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif, dimana peneliti mencoba mendeskripsikan epistemological obstacle yang terjadi pada siswa dalam menyelesaikan soal cerita matematika. Adapun epistemological obstacle yang dianalisis dalam penelitian ini adalah miskonsepsi/kesalahan konsep, kesalahan prosedur dan, sedangkan gaya kognitif yang dikategorikan dalam penelitian ini adalah field dependent dan field independent. Analisis data pada penelitian ini diolah menggunakan statistic deskriptif kualitatif dan melalui tiga alur kegiatan yaitu reduksi data, penyajian data dan verifikasi data atau penarikan kesimpulan dan digunakan untuk mendapatkan jawaban yang bersifat deskriptif berdasarkan data tes dan wawancara. Tes Group Embedded Figures Test (GEFT) yang digunakan untuk mengetahui kategori gaya kognitif yang dimiliki siswa yang nantinya akan dikategorikan menjadi field independent dan field dependent. Sedangkan tes soal cerita matematika materi operasi hitung pecahan yang nantinya akan dianalisis epistemological obstaclenya. Wawancara dilakukan untuk menggali informasi dari subjek penelitian tentang epistemological obstacle yang terjadi pada siswa dalam menyelesaikan soal cerita matematika berdasarkan gaya kognitif. Berdasarkan hasil penelitian yang telah dilakukan, terungkap bahwa siswa dengan bidang field independen dan field dependen masih sering membuat miskonsepsi, kesalahan prosedural, kesalahan teknis dalam menyelesaikan materi soal matematika dalam operasi penghitungan pecahan.
PENGARUH MATH ANXIETY, SELF-EFFICACY, TINGKAT PENDIDIKAN IBU, DAN SUMBER BELAJAR DI RUMAH TERHADAP CAPAIAN LITERASI MATEMATIKA SISWA INDONESIA
Authors: Haryanto Bakir , Setiadi Hari
Published: January 2021

Studi PISA 2012 menunjukkan lemahnya kompetensi siswa Indonesia dalam menyelesaikan soal matematika di tingkat penilaian internasional. Penelitian ini membandingkan faktor-faktor yang diduga mempengaruhi capaian tersebut seperti kondisi psikologi siswa (math anxiety dan self-efficacy), tingkat pendidikan ibu dan fasilitas belajar di rumah antara siswa Indonesia dengan siswa di negara-negara yang berada di peringkat atas penilaian PISA 2012 seperti Cina, Jepang, Finlandia dan Australia. Di samping itu studi ini juga menguji faktor-faktor mana yang berpengaruh secara signifikan terhadap capaian matematika siswa Indonesia menggunakan model regresi berganda. Hasil dari analisis data menunjukan math anxiety, self-efficacy, sumber belajar di rumah, dan tingkat pendidikan ibu berpengaruh secara signifikan terhadap literasi matematika siswa siswa Indonesia.
Crossing the Threshold of Cyborgization
Authors:   Biological Sciences, Moscow State University, Grinin Anton , Grinin Leonid ,   The Institute of Oriental Studies of the Russian Academy of Sciences (RAS), Moscow; Eurasian Center for Big History & System Forecasting
Published: January 2021

Cyborgization is a hot topic these days. This is an intriguing process that is the subject of many futuristic novels and which at the same time takes place right before our eyes. In the present article we discuss the development of cyborgization, its place in Big History, its background and future directions, as well as the problems and risks of this interesting process. The authors are concerned about the question of whether the time will come when a person will mainly or completely consist not of biological, but of artificial material. The article also touches upon other problems and risks associated with future scientific and technological progress.
Estudio sobre la aplicación de la Ley Contra la Violencia Doméstica.
Authors: Molina Blanco Leticia
Published: January 2021

Este trabajo es un estudio, que presenta una óptica de la promulgación legislativa sobre violencia doméstica de un país Latinoamericano, Costa Rica, preocupado por tratar de dar contenido normativo de contención a uno de los males que más afectan a la humanidad: la agresión dentro del hogar. Se trata de una normativa, relativamente joven, que ha encontrado una serie de limitaciones para su buena y correcta aplicación, y encierra situaciones del diario vivir que trascienden los estrados judiciales. Por eso es importante un análisis de su estado actual, con una breve exposición de los antecedentes legislativos que la justificaron y algunas recomendaciones, que le darían mayor viabilidad para el cometido que le dio su creación.
Expanding the conservation genomics toolbox: incorporating structural variants to enhance functional studies for species of conservation concern
Authors: Wold Jana , Galla Stephanie , Eccles David , Hogg Carolyn J. , Koepfli Klaus-Peter , Lec Marissa Le , Guhlin Joseph , Price Kylie , Roberts Joanna , Steeves Tammy
Published: January 2021

Increased capability in the conservation genomics community, combined
with decreased sequencing costs, is providing new opportunities for the
application of whole-genome sequence data to enhance species recovery.
Indeed, assessments of genome-wide diversity based on SNP data are
already informing the conservation management of threatened species
around the world. However, SNP data alone may not sufficiently capture
all of the information necessary for the effective conservation
management of critically endangered species that suffer from severe
inbreeding depression. For threatened species that require significant
intervention, it is critical that we as conservation genomicists expand
our repertoire to include assessments of functional diversity.
Structural variants are a likely source of functional diversity, as
their frequency and genomic context affect the dosage and regulation of
gene expression through mechanisms that alter genome organization and
impact fitness. In this future-focused Opinion, we leverage the existing
literature - predominantly focused on model and agricultural species -
to identify pan-genomic and chromosomic approaches for readily
characterizing structural variants and to consider how integrating these
into the conservation genomics toolbox will transform the way we manage
some of the world’s most threatened species.
Haplotypes within tandemly duplicated candidate genes at BnaA9.MRP5 modulate phytate concentration in canola (Brassica napus L.)
Authors: Liu Haijiang , Li xiaojuan , Zhang Qianwen , yuan pan , Liu Lei , King Graham , Ding Guangda , Wang Sheliang , Cai Hongmei , Wang Chuang , XU Fangsen , Shi Lei
Published: January 2021

Phytate is the storage form of phosphorus in angiosperm seeds and plays
vitally important roles during seed development. However, in crop plants
phytate decreases bioavailability of seed-sourced mineral elements for
humans, livestock and poultry, and contributes to phosphate-related
water pollution. However, there is little knowledge about this trait in
oilseed rape B. napus (oilseed rape). Here, a panel of 505 diverse B.
napus accessions was screened in a genome-wide association study (GWAS)
using 3.28 x 106 single nucleotide polymorphisms (SNPs). This identified
119 SNPs significantly associated with phytate concentration (PA_Conc)
and phytate content (PA_Cont) and six candidate genes were identified.
Of these, BnaA9.MRP5 represented the candidate gene for the significant
SNP chrA09_5198034 (27kb) for both PA_Cont and PA_Conc. Transcription
of BnaA9.MRP5 in a low -phytate variety (LPA20) was significantly
elevated compared with a high -phytate variety (HPA972). Association and
haplotype analysis indicated that inbred lines carrying specific SNP
haplotypes within BnaA9.MRP5 were associated with high- and low-phytate
phenotypes. No significant differences in seed germination and seed
yield were detected between low and high phytate cultivars examined.
Candidate genes, favorable haplotypes and the low phytate varieties
identified in this study will be useful for low-phytate breeding of B.
napus.
Confidential enquiry into maternal deaths in the Netherlands, 2006-2018: a retrospective cohort study
Authors: Kallianidis Athanasios , Schutte Joke , Schuringa Louise , Beenakkers Ingrid , Bloemenkamp Kitty , Braams-Lisman Babette , Cornette Jerome , Kuppens Simone , Rietveld Anna , Schaap Timme , Stekelenburg Jelle , Zwart Joost , Akker Thomas van den
Published: January 2021

Objective: To calculate maternal mortality ratio (MMR) for 2006-2018 in
the Netherlands and compare with 1993-2005. Describe women’s and
obstetric characteristics, causes of death and improvable factors.
Design: Prospective cohort study. Setting: Nationwide. Population:
2,304,271 livebirths. Methods: Analysis of all maternal deaths between
January 1st, 2006, and December, 31st, 2018 as reported to and audited
by the national Audit Committee Maternal Mortality and Morbidity. Main
outcome measures: MMR, causes of death, improvable factors. Results:
Overall MMR was 6.2 per 100,000 livebirths, a decrease from 12.1 in
1993-2005 (Odds Ratio (OR) 0.5, 95%CI 0.4-0.6). Women with non-Western
ethnic background had a slightly increased MMR compared to Dutch women
(MMR 6.5 vs 5.0, OR 1.3, 95%CI 0.9-1.9), and was particularly increased
among women with a background from Surinam/Dutch Antilles (MMR 14.7 OR
2.9, 95%CI 1.6 – 5.3). Half of all women had an uncomplicated medical
history (79/161, 49.1%). Of 172 pregnancy-related deaths within one
year postpartum, 103 (60%) had a direct and 69 (40%) an indirect
cause. Leading causes within 42 days postpartum were cardiac disease
(n=21, 14.8%), hypertensive disorders (n=20, 14.1%) and thrombosis
(n=19, 13.4%). For deaths up to one year postpartum, suicide was the
third commonest cause (n=20, 11.6%). Improvable factors in care were
identified in 76 (47.5%) of all deaths. Conclusions: Maternal mortality
halved in 2006-2018 compared to 1993-2005. Unlike before, cardiac
disease outnumbered hypertensive disorders as main cause of death. Women
with a background from Surinam/Dutch Antilles had a threefold higher
risk of death compared to Dutch women.
Intervención psicológica para el aumento motivacional hacia la actividad física y la pérdida de peso
Authors: Peris-Delcampo David , Cantón Enrique
Published: January 2021

Se presenta un estudio de caso con una joven de 22 años (estudiante y entrenadora de baloncesto) que quería motivarse para perder peso y desarrollar hábitos saludables (buena alimentación y ejercicio físico regular). Se utilizó el modelo “La Jirafa de Cantón” como base de la intervención que consta de cuatro partes bien diferenciadas que son: la “cabeza” o meta; el “cuello” o las expectativas x valor; el “cuerpo” o la autoestima, autoeficacia y autoconcepto; y las “patas” de la base que se refieren a las cuatro vías de obtención de información (experiencia directa, experiencia indirecta, persuasión verbal y síntomas psicofisiológicos). El análisis de datos tanto cuantitativos como cualitativos se realizó mediante triangulación metodológica, midiendo en la participante las partes del modelo de la Jirafa de Cantón de manera cualitativa, y cuantitativamente el bienestar psicológico y la autoeficacia. Los resultados muestran una mejora de las variables motivacionales relacionadas con las partes del modelo, en consonancia con la mejora de las puntuaciones cuantitativas de bienestar psicológico y autoeficacia. También se observó un aumento y mantenimiento de hábitos saludables de nutrición, actividad física y pensamientos adecuados. Estos resultados están en la línea de los obtenidos en estudios anteriores similares.
Fractional Charge of Quarks and Fractal Properties of Hadrons
Authors:   Department of Physics, Adamas University, Kolkata, India, Bhattacharya A. , Pal S. ,   Department of Physics, Basanti Devi College, Kolkata,700029 India, Bhattacharya D. S. ,   Julius-Maximilians University of Würzburg, Germany, Dhara P. ,   Department of Physics, Adamas University, Kolkata, India
Published: January 2021

The origin of fractional charge of a quark is investigated considering the fractal structure of a hadron. Hadron is suggested to be a fractal object with fractal dimension 9/2. Describing quark as a quasiparticle in an analogy with quasi particle in Fractional Quantum Hall Effect, the filling factors are extracted which show large fractional plateau. It is suggested that quarks behave like quasi particles and the fractional charges of quarks can be attributed to the fractal behavior of a hadron.
Unrecognized tuberculosis in a patient with COVID-19
Authors: Stjepanovic Mihailo , Belic Slobodan , Buha Ivana , Maric Nikola , Baralic Marko , Mihailovic-Vucinic Violeta
Published: January 2021

Introduction. COVID-19 is responsible for the current global pandemic. Globally, over 15 million people are currently infected, and just over 600,000 have died due to being infected. It is known that people with chronic illnesses and compromised immune systems can develop more severe clinical presentation. Tuberculosis (TB) is still one of the biggest epidemiological problems worldwide. Both of these diseases can be misdiagnosed and can manifest in a similar way. We will present a case study of a patient who was initially treated as a COVID-19 infection, with TB being diagnosed later on. The recovery began only after being treated for both diseases simultaneously. Case report. The patient is a 27-year-old male, non-smoker, with no history of any significant diseases. He presented with fever, fatigue and hemoptysis. Computed tomography pulmoangiography had shown massive consolidations and excavations, which could be caused by COVID-19. Despite being treated for COVID-19, there was no clinical improvement. On the follow-up chest X-ray, beside signs of COVID-19, there were also changes that could indicate TB. TB was detected in sputum, using PCR and Mycobacteria Growth Indicator Tube, and only after being treated for both diseases did his condition improve. Conclusion. There are a few reported cases of COVID-19 and TB coinfections, and we believe that there are many more patients with this coinfection being unrecognized
How well do integrated 3D models predict alveolar defects after treatment with clear aligners?
Authors: Jiang Ting , Wang Jian Kai , Jiang Yang Yang , Hu Zheng , Tang Guo Hua
Published: January 2021

Objectives

To evaluate the accuracy of integrated models (IMs) constructed by pretreatment cone-beam computed tomography (pre-CBCT) in diagnosing alveolar defects after treatment with clear aligners.

Materials and Methods

Pre-CBCT and posttreatment cone-beam computed tomography (CBCT) scans from 69 patients who completed nonextraction treatment with clear aligners were collected. The IMs comprised anterior teeth in predicted positions and alveolar bone from pre-CBCT scans. The accuracy of the IMs for identifying dehiscences or fenestrations was evaluated by comparing the means of the defect volumes, absolute mean differences, and Pearson correlation coefficients with those measured from post-CBCT scans. Defect prediction accuracy was assessed by sensitivity, specificity, positive predictive values, and negative predictive values. Factors possibly affecting changes in mandibular alveolar defects were analyzed using a mixed linear model.

Results

The IM measurements showed mean deviations of 2.82 ± 9.99 mm3 for fenestrations and 3.67 ± 9.93 mm3 for dehiscences. The absolute mean differences were 4.50 ± 9.35 mm3 for fenestrations and 5.17 ± 9.24 mm3 for dehiscences. The specificities of the IMs were higher than 0.8, whereas the sensitivities were both lower (fenestration = 0.41; dehiscence = 0.53). The positive predictive values were unacceptable (fenestration = 0.52; dehiscence = 0.62), and the overall reliability was low (<0.80). Molar distalization and proclination were positively correlated with significant increases in alveolar defects at the mandibular incisors after treatment.

Conclusions

Alveolar defects after clear aligner treatment cannot be simulated accurately by IMs constructed from pre-CBCT. Caution should be taken in the treatment of crowding with proclination and molar distalization for the safety of alveolar bone at the mandibular incisors.
Does the rhythm and appliance type of rapid maxillary expansion have an effect on root resorption?
Authors: Malkoç Sıddık , Alçin Rukiye , Uzel Aslıhan
Published: January 2021

Objectives

To evaluate the volume, amount, and localization of root resorption in the upper first premolars by micro–computed tomography (micro-CT) after three different rapid maxillary expansion appliances and two different activation rhythms.

Materials and Methods

The patients were divided into three groups; Hyrax, acrylic cap splint (ACS), and full coverage acrylic bonded (FCAB) appliances. Each group was then divided into the following two subgroups: rapid maxillary expansion (RME) and semirapid maxillary expansion (SRME). After expansion was completed, the appliances were stabilized for 12 weeks during the retention period. For each group, 10 premolars (for a total of 60 premolars) were scanned with the micro-CT (SkyScan). The reconstructed 3D images of each root sample were divided into six regions. The resorption craters on these six different root surfaces were analyzed by special CTAn (SkyScan) software for direct volumetric measurements. Kruskal-Wallis one-way analysis of variance and Mann-Whitney U tests were used for statistical analysis.

Results

The total volume of root resorption was less with FCAB than with ACS and Hyrax (P < .001). In all groups, a greater volume of resorption was found on the buccal surface than on the lingual surface (P < .001). No significant differences were found between the RME and SRME groups (P > .05).

Conclusions

All expansion appliances caused root resorption in the upper first premolar teeth, but FCAB may be safer in terms of root resorption. The resorption craters were generally concentrated on the buccal surface. There was no effect of activation rhythm on root resorption.
Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress
Authors: Montaser Hossam , Patel Kashyap A. , Balboa Diego , Ibrahim Hazem , Lithovius Väinö , Näätänen Anna , Chandra Vikash , Demir Korcan , Acar Sezer , Ben-Omran Tawfeg , Colclough Kevin , Locke Jonathan M. , Wakeling Matthew , Lindahl Maria , Hattersley Andrew T. , Saarimäki-Vire Jonna , Otonkoski Timo
Published: January 2021

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)–resident protein that plays a crucial role in attenuating ER stress responses. Although MANF is indispensable for the survival and function of mouse β-cells, its precise role in human β-cell development and function is unknown. In this study, we show that lack of MANF in humans results in diabetes due to increased ER stress, leading to impaired β-cell function. We identified two patients from different families with childhood diabetes and a neurodevelopmental disorder associated with homozygous loss-of-function mutations in the MANF gene. To study the role of MANF in human β-cell development and function, we knocked out the MANF gene in human embryonic stem cells and differentiated them into pancreatic endocrine cells. Loss of MANF induced mild ER stress and impaired insulin-processing capacity of β-cells in vitro. Upon implantation to immunocompromised mice, the MANF knockout grafts presented elevated ER stress and functional failure, particularly in recipients with diabetes. By describing a new form of monogenic neurodevelopmental diabetes syndrome caused by disturbed ER function, we highlight the importance of adequate ER stress regulation for proper human β-cell function and demonstrate the crucial role of MANF in this process.
"There is Always Violence": An Exploratory Study of Phnom Penh, Cambodia, Street-Involved Children
Authors:   Up! International, Davis Jarrett , Miles Glenn ,   Oxford Centre for Mission Studies, Mosebach-Kornelsen Erika ,   Independent Research Consultant, Blackburn Sean ,   Independent Research Consultant
Published: January 2021

As the economic center of Cambodia, Phnom Penh has long been a hotspot for street-involved children and families. While violence is a common facet of life on the street, risk and vulnerability among children is notoriously difficult to measure. Most large-scale surveys tend to sample children within homes and schools, which overlook street-involved children who are commonly unregistered, irregularly attend school, and live outside of houses. This research paper is one of a series of studies on such groups in Southeast Asia. The study conducted 94 semi-structured interviews with street-involved children eight to 18 years of age in Phnom Penh. Physical violence is indicated by the vast majority (77%) of respondents, with significant rates of violence from parents and teachers. Sexual violence is also common, reported by one-in-four (25%), and nearly twice as prevalent among males. As an exploratory study, this research aims to provide a resource for local practitioners and policymakers, and to inform future research.
Analisa Penerimaan dan Penggunaan Sistem Informasi Desa (SID) dengan Model Unified Theory of Acceptance and Use of Technology (UTAUT)
Authors: Tresnawan I Gusti Putu Yudha , Pradnyana I Made Ardwi , Wirawan I Made Agus
Published: January 2021

Sistem Informasi Desa merupakan perangkat teknologi dan aplikasi perangkat lunak yang dioperasikan oleh perangkat desa untuk mengelola data administrasi dan informasi desa. Penelitian ini bertujuan untuk mengetahui faktor yang mempengaruhi minat pemanfaatan dan perilaku penggunaan SID dengan model Unified Theory Of Acceptance And Use Of Technology (UTAUT). Model UTAUT memiliki empat variabel bebas yaitu ekspektasi kinerja, ekspektasi usaha, pengaruh sosial, dan kondisi yang memfasilitasi. Model UTAUT juga memiliki dua variabel terikat yaitu minat pemanfaatan dan perilaku penggunaan serta variabel moderator yaitu jenis kelamin, umur, pengalaman, dan kesukarelaan pengguna. Sampel dalam penelitian ini berjumlah 56 orang. Data diperoleh dengan cara menyebarkan kuisioner kepada operator desa sebagai pengguna SID. Data kemudian dianalisis menggunakan software SmartPLS 3.0. Hasil penelitian ini menunjukkan bahwa (1) Ekspektasi kinerja berpengaruh positif terhadap minat pemanfaatan sebesar 59%, ekspektasi usaha berpengaruh positif terhadap minat pemanfaatan sebesar 49,5 % dan pengaruh sosial tidak berpengaruh positif terhadap minat pemanfaatan. (2) Kondisi yang memfasilitasi berpengaruh positif terhadap perilaku penggunaan sebesar 29,2% dan minat pemanfaatan berpengaruh positif terhadap perilaku penggunaan sebesar 32,3%. (3) Variabel moderator jenis kelamin dan umur tidak memperkuat hubungan antara ekspektasi kinerja terhadap minat pemanfaatan. (4) Variabel moderator jenis kelamin, umur dan pengalaman tidak memperkuat hubungan antara ekspektasi usaha terhadap minat pemanfaatan. (5) Variabel moderator jenis kelamin, umur, pengalaman dan kesukarelaan pengguna tidak memperkuat hubungan antara pengaruh sosial terhadap minat pemanfaatan. (6) Variabel moderator umur dan pengalaman tidak memperkuat hubungan antara kodisi yang memfasilitasi dengan perilaku penggunaan.
Analisis Faktor-faktor yang Mempengaruhi Perilaku Penggunaan Sistem E-Learning Undiksha dengan Model Unified Theory of Acceptance and Use of Technology (UTAUT)
Authors: Sukarya I Gede Arya , Pradnyana I Made Ardwi , Sugihartini Nyoman
Published: January 2021

Sistem E-learning dikembangkan oleh Undiksha untuk meningkatkan efektivitas dan kualitas pembelajaran. Namun pada kenyataannya E-learning Undiksha belum dimanfaatkan secara maksimal oleh dosen di lingkungan Undiksha. Pengguna dapat menerima dan menggunakan sistem adalah hal yang penting untuk dapat mengetahui tingkat keberhasilan dari implementasi sistem tersebut. Oleh karena itu penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi perilaku penggunaan sistem E-learning Undiksha dengan model Unified Theory of Acceptance and Use of Technology (UTAUT). UTAUT merupakan salah satu model penerimaan teknologi yang menggabungkan delapan teori penerimaan teknologi sebelumnya. UTAUT memiliki empat konstruk utama yaitu ekspektasi kinerja, ekspektasi usaha,  pengaruh sosial dan kondisi yang memfasilitasi. Data diperoleh dengan cara menyebarkan kuesioner tertutup dengan sampel 64 Dosen Undiksha. Dianalisis menggunakan software SPSS. Hasil penelitian ini menunjukkan bahwa (1) Ekspektasi kinerja, ekpektasi usaha, pengaruh sosial dan kondisi yang memfasiitasi berpengaruh positif terhadap perilaku penggunaan sistem E-learning Undiksha (2) Variabel moderator jenis kelamin memperkuat hubungan ekspektasi kinerja dan ekspektasi usaha terhadap perilaku penggunaan sistem E-learning Undiksha sedangkan untuk variabel moderator jenis kelamin memperlemah hubungan variabel pengaruh sosial terhadap perilaku penggunaan sistem E-learning Undiksha (3) Variabel moderator umur memperkuat hubungan variabel ekspektasi kinerja, ekspektasi usaha, pengaruh sosial dan kondisi yang memfasilitasi terhadap perilaku penggunaan sistem E-learning Undiksha (4) Variabel moderator pengalaman memperkuat hubungan ekspektasi usaha, pengaruh sosial dan kondisi yang memfasilitasi terhadap perilaku penggunaan sistem E-learning Undiksha.
Panji Sakti “The King of Buleleng” : Game 3D Cerita Rakyat Berbasis Desktop
Authors: Pratama Putu Gilang , Santyadiputra Gede Saindra , Antara Kesiman Made Windu
Published: January 2021

Game 3D cerita rakyat berbasis desktop ini menceritakan tentang riwayat hidup dari Panji Sakti atau sering dikenal juga sebagai Ki Barak Panji Sakti yang merupakan raja pertama Buleleng. Akan tetapi masih banyak masyarakat yang tidak mengetahui tentang cerita rakyat Panji Sakti. Terbukti dari angket yang disebar peneliti. Selain itu media untuk menceritakan cerita rakyat Panji Sakti masih dalam bentuk buku, dimana ini merupakan bentuk kuno di zaman yang sudah modern. Yang mengakibatkan kurangnya minat untuk mengetahui cerita Panji Sakti itu sendiri. Tujuan dari penelitian ini adalah untuk mengimplementasikan rancangan game 3D cerita rakyat Panji Sakti yang nantinya dapat menambah minat masyarakat untuk melestarikan cerita rakyat Panji Sakti. Game 3D cerita rakyat ini menggunakan metode Game Development Life Cycle. Hasil akhir dari game ini berupa program executable.
Seasonality in Freight Rates
Authors: Raju Totakura Bangar , Chauhan Pradeep , Tiwari Saurabh , kashav Vishal
Published: January 2021

This paper inspects in detail the seasonality (deterministic) in container freight rates, and compares seasonality patterns in different freight rate indices. A deterministic seasonality unit root test is performed to achieve set objectives. This study concludes that all the indices (tested in this paper) exhibit significant deterministic seasonality. For January and August, there is no seasonal effect observed in all five series. At the same time, all the indices except Exports from Europe Rate Index (EEI) exhibit significant seasonal patterns in February, September, and December. All five indices exhibit significant seasonality during May, and the coefficient sign shows a drop in the freight rates. During March, October, and November; it is observed that only EEI exhibit significant seasonal patterns. The results could be beneficial for carriers and agents who are involved in the containerised freight transport business. Also, shippers could get a clear idea about the freight rates' nature across various trade routes.
Evaluation of Logistics Service for Multimodal Transport via the Trans-Siberian Railway: A Perspective of Shippers in South Korea
Authors: Kim Gi-Su , Lee Sung-Woo , Kim Chang-Soo , Seo Young-Joon
Published: January 2021

The role of logistics service provider (LSP) is essential for efficient logistics service quality (LSQ) and supply chain management, especially in multimodal transport. Multimodal transport routes that use the Trans-Siberian Railway (TSR) play an important role in the supply chains of Northeast Asia. This paper aims to identify current conditions of TSR LSQ and propose improvements to enhance the competitiveness of traditional routes. Therefore, this study sheds light on and provides recommendations for various managerial strategies to LSPs in the context of the TSR. This study utilizes Importance-Performance Analysis (IPA) to measure levels of importance and performance of the logistics service of LSPs that provide multimodal transport services via the TSR from South Korea to Europe. This study identifies capabilities on the basis of five criteria (price, timeliness, reliability, equipment systems, and customer service) from a customers’ perspective. The results of the research indicate that operational improvements should be considered to activate TSR multimodal transport for northern logistics routes from the perspective of Korean shippers. Specific findings show that balanced development strategies are needed for logistics routes that have not yet been significantly activated, while implying that logistics costs could be reduced initially to satisfy shippers. This study presents an operational strategy for LSPs using the TSR in northern logistics through IPA methods. Furthermore, this research can help policymakers propose specific policies to revitalize the northern logistics of Korean logistics companies and to provide incentive supports for shippers.
Subjective and Objective Analysis of Schedule Delaying Factors for Container Shipping Lines
Authors: Lin Cheng-Wei , Hsu Wan-Chi Jackie , Su Hui-Ju
Published: January 2021

The shipper selects a suitable shipping route and plans for a voyage in order to import and export cargo on the basis of published sailing schedules. The reliability of the sailing schedule will influence the shipper’s logistics expense, which means that the logistics costs will depend on the reliability of schedules published by container shipping companies. Therefore, it is important to consider factors which can cause delays would for container ships sailing on sea routes. The reliability of published sailing schedules can be affected by a number of different factors. This study adopts the multi-criteria decision making (MCDM) method to estimate the importance of the delaying factors in a sailing schedule. In addition, the consistent fuzzy preference relations (CFPR) method is applied to identify the subjective importance (weights) of the delaying factors. The entropy weight method combined with the actual performance of the container shipping company are both used when estimating the objective importance (weights) of the delaying factors. According to the analysis results, the criteria can be divided into four quadrants with different management implications, which indicate that instructions for chase strategy, sailing schedule control, fleet allocation, transship operation arrangement and planning for ports in routes are often ignored by container shipping companies. Container shipping companies should consider adjusting their operational strategies, which would greatly improve their operational performance.
Could Deglobalization Kill Transnational Cooperation? A Brief Historical Lesson
Authors: Rab Virág
Published: January 2021

The study examines a historical period referred to in the literature as deglobalization. After the First World War, economic nationalism gained ground in some countries, mainly for political reasons, characterized by protectionist economic policies and the pursuit of autarchy/self-sufficiency. There were no international regulations or well-functioning international institutions that would have facilitated economic cooperation. How did those who worked hard to reconstruct the European economy react to this situation? This study presents this through the process of developing an informal network of bankers, and it indirectly highlights some important links between informal networks, globalization, and deglobalization.
Global Trends in Tobacco Cigarette Use among Adolescents: Prevalence of Use and Evidence Based Cessation Interventions
Authors: Addae Rejoic
Published: January 2021

Tobacco use remains a global problem, and as a demographic group, adolescents are at a high risk of its adverse effects. In addition, disparities exist in strategies to address tobacco control, particularly among youth from low-socioeconomic backgrounds. The health risks associated with tobacco use provide a compelling reason for all nations to prioritize addressing and regulating its use and providing sustainable funding sources for training healthcare professionals and others under Article 14 of the World Health Framework Convention on Tobacco Control (FCTC). This article has four primary goals: (1) to provide an overview of the 2005 World Health Organization’s international public health treaty - the World Health FCTC; (2) to examine the prevalence of tobacco cigarette use among adolescents globally and the impact of cultural/social influences on use; (3) to provide an overview of current evidence based smoking cessations interventions that have shown success with this group; and (4) to discuss the overarching social work implications and practice when working with adolescents who use tobacco cigarettes.
Classification of Business Ecosystems of the Russian Territory Bordering China
Authors: Sazanova S. L.
Published: January 2021

The theory of business ecosystems is becoming more and more popular in modern economic science, there is more and more applied research of business ecosystems in individual industries and territories. At the same time, there is no unified classification of business ecosystems in modern economic science. The works of Russian and foreign scientists mention digital ecosystems, technological ecosystems, communication ecosystems, but they are all considered in the sectoral and / or cross-sectoral context, without any connection with a specific territory. Thus, despite the initially ecological primary source of the concept of "ecosystem", the territorial aspect of business ecosystems is insufficiently studied, in our opinion. The article provides a classification of business ecosystems of the Russian border with China on the basis of a systemic economic approach for further study, forecasting and management of socio-economic ecosystems of business in border areas.
Gelombang Pop Culture Tik-Tok: Studi kasus Amerika Serikat, Jepang, India dan Indonesia
Authors: Kusumawardhani Elisa , Sari Deasy Silvya
Published: January 2021

This article discusses TikTok as a global pop culture wave, with case studies in the United States, Japan, India and Indonesia. TikTok is a popular culture that does not come from the West but is able to develop and spread throughout the world and is accepted by the community. In fact, TikTok is growing rapidly in the United States, where the United States is often regarded as a source of popular culture. The author uses the concepts of culture, pop culture and globalization, as well as literature studies to study the wave of pop culture TikTok. The author found that in terms of applications, TikTok is able to compete with twitter, Instagram, facebook, linkedIn, etc. TikTok applications are able to adapt to the domestic market in terms of content and culture because it has a local team in the development of specialized content. TikTok often faces challenges so it is considered a bad application in terms of culture that does not fit the local context or is considered to have political tendencies. However, TikTok always improves in dealing with these issues
Pengembangan Bahan Ajar Berbasis Multimedia Interaktif Dalam Meningkatkan Minat Belajar Matematika Siswa
Authors: Nuritno Rizqi , Raharjo Hendri , Winarso Widodo
Published: January 2021

This research is a form of interactive multimedia development as a resource that aims to: 1) Develop Interactive Multimedia Learning Material and Beam Cube; 2) Determine the feasibility of Cube Interactive Multimedia Learning Material and Beam; 3) Increasing interest in learning math using the Interactive Multimedia Learning Material and Beam Cube. This research method is the Research and Development (R & D), adapted from ADDIE development model, with the following steps: 1) Analysis,2) Design,3) Development,4) Implementation5) Evaluation.Validation is done by two people matter experts and two experts media. Teaching materials developed tested to 5 learners VIII class A and 31 learners in class VIII B of SMP Negeri 12 Cirebon. Feasibility level Interactive Multimedia-Based Instructional Materials and Beam Cube based assessment: 1) Matter Experts obtained an average value of 4.2 which is included in the category of Good, 2) Expert Media obtained an average value of 4.26 are included in the category of Very Good, 3) learners field trials obtained an average value of 4.26 are included in the category of Very Good. Thus the Interactive Multimedia-Based Instructional Materials and Beam Cube is good and fit for use as teaching material. Based on the analysis Interest in Learning students before and after the use of the Interactive Multimedia-Based Instructional Materials and Beam Cube, obtained by N-gain of 0.405 which is included in the category of Medium of the total score early 2026 into 2521. In the test paired t test obtained t count equal to -16.619 with sig , 0,000 showed significant measurement so that the conclusion is the development of Interactive Multimedia-Based Instructional Materials and Beam Cube can improve Students Interest in Learning Mathematics.
Media Pembelajaran Interaktif Berbasis Augmented Reality (AR) Untuk Meningkatkan Motivasi Belajar Anak
Authors: Iksan Nur , Djuniadi Djuniadi
Published: January 2021

Based on observations related to the increasing interest of children to digital devices (smartphones, laptops), become an opportunity for teachers/educators to make ICT-based learning media with more interactive and interesting, thus improving motivation to learn children. One of the methods that can be used is Augmented Reality. Augmented Reality (AR) is a technology that can incorporate a 3D object into a real environment using a webcam medium. The advantages of this AR method is an interesting visual appearance because it can display 3D objects that seem to exist in the real environment. AR method also has advantages of the interactive side because it uses markers to display certain 3D objects that are pointed to the webcam. In addition, the application of concepts to be used can improve the reasoning power and imagination of learners.
Sistem Seleksi Penerimaan Siswa Baru Menggunakan Metode Weighted Product
Authors: Mayhendra Bella , Sokibi Petrus
Published: January 2021

The Acceptance of new students in SMA Negeri 1 Rajagaluh is done by choosing alternate prospective students who qualify based on predetermined variables. The problem faced by the team of selectors is how to determine the best students from a number of prospective students who have advantages and disadvantages of each with a very fast time so often mistakes in the selection of new students in SMA Negeri 1 Rajagaluh and less objective in providing an assessment for selected. In this thesis built a new decision support selection system using the method of Weighted Product (WP). The variables used in the selection of admissions in SMA Negeri 1 Rajagaluh are the national final examination scores, the final examination score of the school, the value of junior high school report cards. This system is designed using PHP programming language (Hypertext Processor File) as well as MySQL database as a database server. This system generates rankings of prospective new students in accordance with the procedure of admission of students in SMA Negeri 1 Rajagaluh, where the result is in the form of student ranking. This system has several advantages that variable and a weight value of variables used in this system is dynamic. This system also has a shortage of the range of values on the variable is still static