bluuebunny/crossref_metadata_2025 huggingface dataset:
A randomized comparison of manual versus mechanical thrombus removal in primary percutaneous coronary intervention in the treatment of ST‐segment elevation myocardial infarction (TREAT‐MI)
Authors: Vink Maarten A. , Patterson Mark S. , Etten Jeroen van , Ijsselmuiden Alexander J.J. , Dirksen Maurits T. , Amoroso Giovanni , Slagboom Ton , Laarman GertJan , Kiemeneij Ferdinand
Published: January 2011

Objectives: The objective of this study was to compare the efficacy and long‐term clinical outcome of manual thrombus aspiration with the Export catheter (Medtronic, Minneapolis, MN) versus mechanical thrombus cutting/aspiration with the X‐sizer system (eV3, White Bear Lake, MN) in primary percutaneous coronary intervention (PPCI). Background: In PPCI for acute ST‐segment elevation myocardial infarction (STEMI), markers of myocardial reperfusion are improved with adjunctive thrombectomy. Previous studies of different devices showed a variability in performance, suitability, and short‐term clinical outcome. In current literature, no direct comparison is available. Methods: We prospectively randomized 201 patients admitted for PPCI for STEMI to either the Export catheter or the X‐sizer prior to stent deployment. Technical success in advancing to and across the lesion, improvement of flow, reduction of thrombus, and the effect on ST‐segment resolution were examined. The primary endpoint of the follow‐up study was the combined endpoint of cardiac death, recurrent myocardial infarction (MI), or target‐vessel revascularization (TVR) at 3 years. Results: Although the Export catheter was more successfully deployed, other procedural parameters were similar with a trend toward better ST‐segment resolution (56.6% vs. 44%; P = 0.06) as compared to the X‐sizer system. The occurrence of the primary clinical endpoint at 3 years was 22.2% and 18.6%, respectively (HR 1.20; 95% CI 0.65–2.22; P = 0.35). Conclusion: Despite shorter procedural times, better lesion crossing, and fewer complications, both surrogate endpoints as well as 3‐year clinical follow‐up were similar with the use of the Export catheter as compared to the X‐sizer system. © 2011 Wiley‐Liss, Inc.
Aspiration coronary thrombectomy for acute myocardial infarction increases myocardial salvage
Authors: Ciszewski Michał , Pregowski Jerzy , Teresińska Anna , Karcz Maciej , Kalińczuk Łukasz , Pracon Radosław , Witkowski Adam , Rużyłło Witold
Published: January 2011

Objectives: The aim of the study was to assess if aspiration thrombectomy in high risk patients with STEMI and angiographic evidence of thrombus may improve myocardial salvage. Background: It is unclear if thrombus aspiration before percutaneous intervention (PCI) improves myocardial salvage. Methods: The trial was a prospective randomized study. The inclusion criteria were: first STEMI within 12 hr from symptoms onset, culprit lesion in left anterior descending or right coronary artery, culprit artery TIMI flow ≤ 2 and angiographic evidence of thrombus. The primary endpoint was myocardial salvage index (MSI) as assessed by 99mTc‐sestamibi SPECT imaging. Results: We randomized 137 patients (98 male, mean age 64.1 ± 12.5 years) either to aspiration thrombectomy followed by standard PCI with stent implantation (n = 67) or to standard primary PCI (n = 70). Index perfusion defect was similar in both study groups: 34.2% ± 13.1% in thrombectomy group versus 37.1% ± 12.0% in primary PCI group (P = 0.2). MSI was larger in aspiration thrombectomy group than in control patients [25.4% (IQR 13.5–44) vs. 18.5% (IQR 7.7–30.3) respectively, P = 0.02]. The final infarct size was smaller in patients treated with aspiration thrombectomy (23.1% ± 13.3% vs. 28.9% ± 10.2% in the control group, P = 0.002). Conclusions: Aspiration thrombectomy improves myocardial salvage in high risk STEMI patients with angiographic evidence of thrombus. © 2011 Wiley‐Liss, Inc.
Acute myocardial infarction caused by multivessel coronary spasm due to calcium channel blocker withdrawal
Authors: Kostis William J. , Suh William M. , Palacios Igor F.
Published: January 2011

Calcium channel blockers are a commonly used class of medications for the management of hypertension, angina, and superventricular tachyarrhythmias. Abrupt withdrawal of these agents can precipitate coronary vasospasm, which may result in myocardial infarction. We present the case of a 47‐year‐old woman who sustained an acute myocardial infarction mediated by multivessel coronary vasospasm secondary to verapamil withdrawal and the associated interventional management. © 2011 Wiley‐Liss, Inc.
Balloon aortic valvuloplasty for congenital aortic stenosis using the femoral and the carotid artery approach: A 16‐year experience from a single center
Authors: Rossi Raul I. , Manica João L.L. , Petraco Ricardo , Scott Mônica , Piazza Luciane , Machado Paulo M.
Published: January 2011

Objectives:The aim of this article is to report a 16‐year experience with percutaneous balloon aortic valvuloplasty (BAVP) in newborns and young infants up to 3 months of age in a tertiary care cardiac reference center in a developing country and to determine its value in postponing open heart surgery. Background:Congenital aortic stenosis (AS) is a potentially life threatening disorder. BAVP and surgical procedures have similar short and medium‐term efficacy. Methods:Thirty‐one consecutive newborns and young infants with critical AS underwent BAVP in our department from 1991 to 2007. Mean patient age at time of the procedure was 22 days (range 2–92 days) and mean weight was 3,310 g (1,840–4,400 g). Results:There was a significant reduction in mean Doppler‐derived peak gradient across the aortic valve immediately after the procedure (75.1 ± 22 versus 32.2 ± 13.02, P < 0.001), and this finding was maintained throughout follow‐up. Since 2003, when the carotid approach became routine practice, no major vascular complications were observed. Mean time of follow‐up was 81 months (5 days–196 months) with only two deaths (7.4%). Only 24% patients required surgical reintervention on the aortic valve during follow‐up. Survival free from aortic valve surgery was 80% at 24 months, 66% at 63 months, and 50% at 80 months. Conclusion:Percutaneous intervention for relief of critical aortic stenosis in newborns in a tertiary center of a developing country is safe and has excellent short and long‐term results comparable to other centers throughout the world. © 2011 Wiley‐Liss, Inc.
Limitations of closing percutaneous transthoracic ventricular access ports using a commercial collagen vascular closure device
Authors: Barbash Israel M. , Saikus Christina E. , Ratnayaka Kanishka , Faranesh Anthony Z. , Kocaturk Ozgur , Wu Vincent , Bell Jamie A. , Schenke William H. , Raman Venkatesh K. , Lederman Robert J.
Published: January 2011

Introduction: Closed‐chest access and closure of direct cardiac punctures may enable a range of therapeutic procedures. We evaluate the safety and feasibility of closing percutaneous direct ventricular access sites using a commercial collagen‐based femoral artery closure device. Methods: Yorkshire swine underwent percutaneous transthoracic left ventricular access (n = 13). The access port was closed using a commercial collagen‐based vascular closure device (Angio‐Seal, St. Jude Medical) with or without prior separation of the pericardial layers by instillation of fluid into the pericardial space (“permissive pericardial tamponade”). After initial nonsurvival feasibility experiments (n = 6); animals underwent 1‐week (n = 3) or 6‐week follow‐up (n = 4). Results: In naïve animals, the collagen plug tended to deploy outside the parietal pericardium, where it failed to accomplish hemostasis. “Permissive pericardial tamponade” was created under MRI, and accomplished early hemostasis by allowing the collagen sponge to seat on the epicardial surface inside the pericardium. After successful closure, six of seven animals accumulated a large pericardial effusion 5 ± 1 days after closure. Despite percutaneous drainage during 6‐week follow‐up, the large pericardial effusion recurred in half, and was lethal in one. Conclusions: A commercial collagen‐based vascular closure device may achieve temporary but not durable hemostasis when closing a direct left ventricular puncture port, but only after intentional pericardial separation. These insights may contribute to development of a superior device solution. Elective clinical application of this device to close apical access ports should be avoided. © 2011 Wiley‐Liss, Inc.
ChemInform Abstract: Synthesis and Crystal Structure of the New Complex Oxide Ca7Mn2.14Ga5.86O17.93.
Authors: Kalyuzhnaya A. S. , Abakumov A. M. , Rozova M. G. , D'Hondt H. , Hadermann J. , Antipov E. V.
Published: January 2011

The title compound is synthesized by solid state reaction of MnO, Ga2O3, and CaO (1000 °C, 150 h).
ChemInform Abstract: Aqueous Telluridoindate Chemistry: Water‐Soluble Salts of Monomeric, Dimeric, and Trimeric In/Te Anions [InTe4]5‐, [In2Te6]6‐, and [In3Te10]11‐.
Authors: Heine Johanna , Dehnen Stefanie
Published: January 2011

The structures of compounds (II)—(VI) and (VIII) are determined by single crystal XRD.
ChemInform Abstract: Room‐Temperature Synthesis of the Highly Polar Cluster Compound Sn[SnCl][W3Cl13].
Authors: Ahmed Ejaz , Groh Matthias , Ruck Michael
Published: January 2011

Dark brown block‐shaped crystals of the title compound are prepared by reaction of stoichiometric amounts of Sn and WCl6 in the ionic liquid [bmim]Cl/AlCl3 (20 °C, 12 h; 43% yield).
ChemInform Abstract: Formation of Nanometric HT‐LiCoO2 by a Precipitation and Aging Process in an Alcoholic Solution.
Authors: Larcher Dominique , Delobel Bruno , Dantras‐Laffont Lydia , Simon Evelyne , Blach Jean‐Francois , Baudrin Emmanuel
Published: January 2011

Nanosized powders of the high‐temperature polymorph of LiCoO2 are precipitated from EtOH solutions of LiNO3 and Co(NO3)2 by addition of KOH at 60 °C.
ChemInform Abstract: Sr3Co2O4.33H0.84: An Extended Transition Metal Oxide‐Hydride.
Authors: Helps Rebecca M. , Rees Nicholas H. , Hayward Michael A.
Published: January 2011

The title compound is prepared by reaction of Sr3Co2O5.80 (obtained from stoichiometric mixtures of SrCO3 and Co3O4 at 1100 °C for 40 h) with CaH2 (Ar, 24 h at 240 °C, 48 h at 250 °C, and 24 h at 255 °C) and its structure is determined by neutron powder diffraction.
ChemInform Abstract: Extended Occupational and Positional Disorder in Pavonite Homologous Copper Bismuth Chalcogenide Halogenides.
Authors: Heerwig Andreas , Thybaut Cyril Louis Jaques , Ruck Michael
Published: January 2011

The crystal structures of compounds (IV), (VI), (VIII), and (IX) are determined by single crystal XRD.
ChemInform Abstract: Formal [4 + 2] Cycloaddition of Alkoxy‐Substituted Donor—Acceptor Cyclobutanes and Aldehydes Catalyzed by Yb(OTf)3.
Authors: Moustafa Mahmoud M. Abd Rabo , Stevens Andrew C. , Machin Ben P. , Pagenkopf Brian L.
Published: January 2011

The reaction is applied to a wide range of aromatic, aliphatic and heteroaromatic aldehydes to afford the fused tetrahydropyran products with complete diastereoselectivity.
ChemInform Abstract: Desymmetrizing Asymmetric Ring Expansion: Stereoselective Synthesis of 7‐Membered Cyclic β‐Keto Carbonyl Compounds with an α‐Hydrogen.
Authors: Hashimoto Takuya , Naganawa Yuki , Maruoka Keiji
Published: January 2011

Ring expansion of symmetrically substituted cyclohexanones with N‐α‐diazoacetyl camphorsultam (II) is devised as a stereoselective approach to functionalized cyclic β‐keto carbonyls having a kinetically stabilized α‐hydrogen.
ChemInform Abstract: Nickel/Lewis Acid‐Catalyzed Aryl‐ and Alkenylcyanation of Unsaturated Bonds.
Authors: Yada Akira , Ebata Shiro , Idei Hiroaki , Zhang Di , Nakao Yoshiaki , Hiyama Tamejiro
Published: January 2011

Lewis acid cocatalysts like organoaluminum and ‐boron compounds accelerate the catalytic cycle of the arylcyanation, allowing for expansion of the scope of aryl cyanides.
ChemInform Abstract: A Green Protocol for Catalytic Conversion of Epoxides to 1,2‐Diacetoxy Esters with Phosphomolybdic Acid Alone or Its Supported on Silica Gel.
Authors: Zeynizadeh Behzad , Sadighnia Leila
Published: January 2011

The reaction is conducted under solvent‐free conditions and shows significant stereospecificity.
ChemInform Abstract: Stereoselective Synthesis of 2‐Carbamoyl‐2‐cyanocyclopropanecarboxylates by Tandem Oxidative Cyclization and Neighboring Group‐Assisted Decarboxylation.
Authors: Wang Hua , Fan Renhua
Published: January 2011

The mild conditions allow the preparation of various title compounds which are of interest as basic skeletons for various transformations.
ChemInform Abstract: Highly Efficient Synthesis of 3‐Amino‐/Alkylthio‐cyclobut‐2‐en‐1‐ones Based on the Cyclization of Acyl Ketene Dithioacetals.
Authors: Zhao Yu‐Long , Yang Shao‐Chun , Di Chong‐Hui , Han Xiao‐Dan , Liu Qun
Published: January 2011

A new strategy for the highly efficient one‐pot synthesis of the title cyclobutenones is developed using a base‐promoted cyclization of dithioacetals (I).
ChemInform Abstract: Catalytic Enantioselective Radical Cyclization via Regiodivergent Epoxide Opening.
Authors: Gansaeuer Andreas , Shi Lei , Otte Matthias
Published: January 2011

The reaction is effective for the chiral and racemic substrates.
ChemInform Abstract: Copper‐ and Phosphine‐Free Sonogashira Coupling Reactions of Aryl Iodides Catalyzed by an N,N‐Bis(naphthylideneimino)diethylenetriamine‐functionalized Polystyrene Resin Supported Pd(II) Complex under Aerobic Conditions.
Authors: Bakherad Mohammad , Amin Amir H. , Keivanloo Ali , Bahramian Bahram , Raeissi Mersad
Published: January 2011

The method allows an easy access to synthetically important acetylene products.
ChemInform Abstract: One‐Pot Synthesis of Conjugated (E)‐Enynones via Two Types of Cross‐Coupling Reaction.
Authors: Hoshi Masayuki , Yamazaki Hirokazu , Okimoto Mitsuhiro
Published: January 2011

Sequential Suzuki and Sonogashira reactions afford the synthetically important target compounds in good to excellent yields.
ChemInform Abstract: Stereospecific Substitution of Allylic Alcohols to Give Optically Active Primary Allylic Amines: Unique Reactivity of a (P,alkene)Ir Complex Modulated by Iodide.
Authors: Roggen Markus , Carreira Erick M.
Published: January 2011

The reaction applies sulfamic acid as an aminating agent, Ir‐phosphoramidite catalyst, generated in situ, and LiI as an additive, the latter being crucial for the high optical purity of the isolated product.
ChemInform Abstract: Highly Enantioselective Synthesis of (Diarylmethyl)amines by Rhodium‐Catalyzed Arylation of N‐Nosylimines Using a Chiral Bicyclo[3.3.0]diene Ligand.
Authors: Wang Li , Wang Zhi‐Qian , Xu Ming‐Hua , Lin Guo‐Qiang
Published: January 2011

The optimized conditions allow the preparation of various optically pure target compounds.
ChemInform Abstract: Asymmetric Alkyl—Alkyl Cross‐Couplings of Unactivated Secondary Alkyl Electrophiles: Stereoconvergent Suzuki Reactions of Racemic Acylated Halohydrins.
Authors: Owston Nathan A. , Fu Gregory C.
Published: January 2011

Carbamate‐protected racemic bromohydrins (II) and its homologue (VIII) are reacted with alkyl boranes to afford the products with high yields and excellent enantioselectivities.
ChemInform Abstract: CuI/L‐Proline‐Catalyzed Selective One‐Step Monoacylation of Styrenes and Stilbenes.
Authors: Prathima P. Sai , Maheswari C. Uma , Srinivas K. , Rao M. Mohan
Published: January 2011

Aryl‐substituted olefins are prone to vicinal dioxygenation under conditions A) to give mono‐acetylated diols.
ChemInform Abstract: Three Component Reaction of Arynes with Cyclic Ethers and Active Methines: Synthesis of ω‐Trichloroalkyl Phenyl Ethers.
Authors: Okuma Kentaro , Fukuzaki Yuta , Nojima Akiho , Sou Ayumi , Hino Haruna , Matsunaga Nahoko , Nagahora Noriyoshi , Shioji Kosei , Yokomori Yoshinobu
Published: January 2011

Reaction of tetrahydropyran, tetrahydrofuran, and oxetanes with in situ prepared benzyne [obtained from (I) and CsF] in the presence of chloroform (III) affords the corresponding ω‐trichlorinated alkyl phenyl ethers in moderate to good yields.
ChemInform Abstract: Synthesis of Aryl Ketones by Palladium(II)‐Catalyzed Decarboxylative Addition of Benzoic Acids to Nitriles.
Authors: Lindh Jonas , Sjoeberg Per J. R. , Larhed Mats
Published: January 2011

A new rapid synthesis of (het)aryl ketones (III) and (V) is achieved by reaction of ortho‐substituted (het)arylcarboxylic acids with simple nitriles in the presence of a Pd(II)—methylbipyridine catalyst system.
ChemInform Abstract: Room Temperature Palladium‐Catalyzed Decarboxylative ortho‐Acylation of Acetanilides with α‐Oxocarboxylic Acids.
Authors: Fang Ping , Li Mingzong , Ge Haibo
Published: January 2011

A wide range of o‐acyl acetanilides is prepared from (I) with aromatic [cf.
ChemInform Abstract: Facile Conversion of Thioamides into the Corresponding Amides in the Presence of Tetrabutylammonium Bromide.
Authors: Inamoto Kiyofumi , Shiraishi Mitsugu , Hiroya Kou , Doi Takayuki
Published: January 2011

In most cases, air can be used as the reagent.
ChemInform Abstract: Solvent‐Free Chemoselective Cyanation of α,α‐Dibromoacetophenones Using Potassium Hexacyanoferrate(II) as an Eco‐Friendly Cyanide Source.
Authors: Zhao Zhouxing , Li Zheng
Published: January 2011

The present new chemoselective cyanation of α,α‐dibromoacetophenones is performed under solvent‐free conditions without any catalyst.
ChemInform Abstract: Efficient Methods for the Synthesis of Arylacetonitriles.
Authors: Stazi Federica , Maton William , Castoldi Damiano , Westerduin Pieter , Curcuruto Ornella , Bacchi Sergio
Published: January 2011

In some cases, the process is more efficient if the transformation proceeds via potassium salts [cf.
ChemInform Abstract: Recyclable NHC‐Ni Complex Immobilized on Magnetite/Silica Nanoparticles for C—S Cross‐Coupling of Aryl Halides with Thiols.
Authors: Yoon Hyo‐Jin , Choi Jung‐Woo , Kang Homan , Kang Taegyu , Lee Sang‐Myung , Jun Bong‐Hyun , Lee Yoon‐Sik
Published: January 2011

The catalyst can be separated magnetically and reused with almost no loss of activity.
ChemInform Abstract: Nickel‐Catalyzed Cross‐Coupling of Non‐Activated or Functionalized Aryl Halides with Aryl Grignard Reagents.
Authors: Xie Lan‐Gui , Wang Zhong‐Xia
Published: January 2011

New nickel complexes can efficiently catalyze cross‐coupling of unactivated and deactivated aryl chlorides and fluorides with aryl Grignard reagents.
ChemInform Abstract: Efficient Preparation of 2‐Aminomethylbiphenyls via Suzuki—Miyaura Reactions.
Authors: Boudreault Pierre‐Luc , Cardinal Sebastien , Voyer Normand
Published: January 2011

The reaction of the arylboronic acid substrates with aryl halides is most effective concerning both yields and reaction time when the amino group is protected by ‐Boc instead of ‐Me.
ChemInform Abstract: Synthesis of Tetrasubstituted Alkenes by Stereo‐ and Regioselective Stannyllithiation of Diarylacetylenes.
Authors: Tsuji Hayato , Ueda Yasuyuki , Ilies Laurean , Nakamura Eiichi
Published: January 2011

The selectivity of the reaction is controlled by subtle steric and electronic effects.
ChemInform Abstract: Gold‐Catalyzed Annulation/Fragmentation: Formation of Free Gold Carbenes by Retrocyclopropanation.
Authors: Solorio‐Alvarado Cesar R. , Echavarren Antonio M.
Published: January 2011

The reaction of a variety of 1,6‐enynes, bearing hydroxy, alkoxy or aryl groups at the benzyl position, naphthalenes [cf.
ChemInform Abstract: Rhenium‐Catalyzed Diastereoselective Synthesis of Aminoindans via the Insertion of Allenes into a C—H Bond.
Authors: Kuninobu Yoichiro , Yu Peng , Takai Kazuhiko
Published: January 2011

Various achiral aromatic amines react with achiral allenes to produce polysubstituted indan skeletons in a completely stereoselective manner.
ChemInform Abstract: Three‐Component, Diastereoselective Synthesis of Highly Functionalized Indan Derivatives Based on an Anionic Domino Sequence from α‐Nitroketones.
Authors: Giorgi Giorgio , Arroyo Francisco J. , Lopez‐Alvarado Pilar , Menendez J. Carlos
Published: January 2011

The convenient one‐pot sequence starts from 1,2‐dialdehydes and α‐nitroketones and proceeds via nitroaldol reaction, retro Dieckmann‐type ring opening and a final intramolecular nitroaldol reaction.
ChemInform Abstract: An Improved and Mild Wenker Synthesis of Aziridines.
Authors: Li Xinyao , Chen Ning , Xu Jiaxi
Published: January 2011

The conventional procedure is modified by employing chlorosulfonic acid for the esterification step.
ChemInform Abstract: Synthesis of β‐Amino‐Functionalized α‐exo‐Methylene‐γ‐butyrolactones via a β‐Lactam Synthon Strategy.
Authors: Takahashi Masaki , Atsumi Jun‐ichi , Sengoku Tetsuya , Yoda Hidemi
Published: January 2011

Ring cleavage of lactams to amino alcohols is followed by Bu4NF‐mediated cyclization to allow the synthesis of a new class of target compounds.
ChemInform Abstract: Silica Sulfuric Acid as a Reusable Heterogeneous Catalyst for the Diastereoselective Mukaiyama Aldol Reaction of 2‐(Trimethylsilyloxy)furan: Facile Synthesis of γ‐Butenolides.
Authors: Sabitha Gowravaram , Prasad M. Nagendra , Ramesh M. , Yadav J. S.
Published: January 2011

The aldehydes (II) cleanly undergo the presented reaction.
ChemInform Abstract: Synthesis of 3‐Trifluoromethylbenzo[b]furans from Phenols via Direct ortho Functionalization by Extended Pummerer Reaction.
Authors: Kobatake Takayuki , Fujino Daishi , Yoshida Suguru , Yorimitsu Hideki , Oshima Koichiro
Published: January 2011

A variety of para‐, ortho‐ and meta‐substituted phenols is directly converted to the target 2‐methylthio‐3‐trifluoromethylbenzofurans in a Tf2O‐mediated reaction.
ChemInform Abstract: Phosphazene Base Catalyzed Intramolecular Cascade Reactions of Aryl‐Substituted Enynes.
Authors: Tang Jian‐Sheng , Xie Ye‐Xiang , Wang Zhi‐Qiang , Deng Chen‐Liang , Li Jin‐Heng
Published: January 2011

The method affords various tricyclic heterocyclic skeletons in good to excellent yields.
ChemInform Abstract: Synthesis and Characterization of Some Biological Active Compounds on the Basis of 2‐Thiophene Carboxylic Acid with Heterocyclic Amines.
Authors: Badiceanu Carmellina Daniela , Draghici Constantin , Missir Alexandru‐Vasile
Published: January 2011

Thioureides (IV) (8 examples) are obtained in a condensation reaction of 2‐thenoyl‐isocyanate with heterocyclic amines under optimized conditions.
ChemInform Abstract: Organocatalytic Direct Vinylogous Michael Addition of α,β‐Unsaturated γ‐Butyrolactam to α,β‐Unsaturated Aldehydes and an Illustration to Scaffold Diversity Synthesis.
Authors: Feng Xin , Cui Hai‐Lei , Xu Shi , Wu Li , Chen Ying‐Chun
Published: January 2011

A number of enantioenriched natural‐product‐like or drug‐like molecules with fused bi‐, tri‐, and polycyclic structures are constructed by synthetic transformations of some prepared Michael‐adducts.
ChemInform Abstract: Thiophene‐Containing Products of the Ugi Reaction in an Oxidation‐Triggered IMDA/Aromatization Cascade: A Simple Access to 3‐Oxoisoindolines.
Authors: Krasavin Mikhail , Parchinsky Vadislav
Published: January 2011

A novel access to 2 skeletally diverse series of functionalized 3‐oxoindoles starts with either thiophene‐containing aldehyde (I) or amine (X).
ChemInform Abstract: Stereocontrolled Creation of All‐Carbon Quaternary Stereocenters by Organocatalytic Conjugate Addition of Oxindoles to Vinyl Sulfone.
Authors: Zhu Qiang , Lu Yixin
Published: January 2011

Highly enantioselective addition of 3‐aryl‐substituted oxindoles (I) and (IV) towards bis(phenylsulfonyl)ethene (II) is achieved in the presence of a quinidine‐derived thiourea catalyst (QDTU) to give oxindoles containing an all‐carbon quaternary stereocenter.
ChemInform Abstract: Tunable Pd‐Catalyzed Cyclization of Indole‐2‐carboxylic Acid Allenamides: Carboamination vs. Microwave‐Assisted Hydroamination.
Authors: Beccalli Egle M. , Bernasconi Alice , Borsini Elena , Broggini Gianluigi , Rigamonti Micol , Zecchi Gaetano
Published: January 2011

The reaction of substrate (I) with aryl iodides provides imidazoindoles like (III).
ChemInform Abstract: Synthesis of Novel N‐Substituted 2‐(Hetero)arylimino‐1,3‐thiazolidin‐4‐ones.
Authors: Revelant Germain , Hesse Stephanie , Kirsch Gilbert
Published: January 2011

In continuation of an ongoing project directed to synthesize novel agonists in the glitazone class, a three‐step procedure for the synthesis of title compounds (VII) is described.
ChemInform Abstract: One‐Pot Tandem Approach for the Synthesis of Benzothiazoles from Benzyl Halides.
Authors: Zhu Chen , Akiyama Takahiko
Published: January 2011

Mild Kornblum conditions without any additional oxidant allow the access to the pharmacologically important heterocyclic system and a range of substituents is tolerated.
ChemInform Abstract: Carboxylic Acid‐Promoted Copper(I)‐Catalyzed Azide—Alkyne Cycloaddition
Authors: Shao Changwei , Wang Xinyan , Xu Jimin , Zhao Jichen , Zhang Qun , Hu Yuefei
Published: January 2011

as a highly efficient method to prepare 1,4‐disubstituted triazoles
ChemInform Abstract: Enantioselective Synthesis of Indole‐Fused Dihydropyranones via Catalytic Cycloaddition of Ketenes and 3‐Alkylenyloxindoles.
Authors: Lv Hui , Chen Xiang‐Yu , Sun Li‐hui , Ye Song
Published: January 2011

The procedure provides a mild and efficient method to prepare optically active heterocyclic scaffolds.
ChemInform Abstract: A Chemoselective Deoxygenation of N‐Oxides by Sodium Borohydride—Raney Nickel in Water.
Authors: Gowda Narendra B. , Rao Gopal Krishna , Ramakrishna Ramesha A.
Published: January 2011

Various functionalized N‐oxides can be successfully reduced in water and most functional groups remain unaffected.
ChemInform Abstract: Tandem Synthesis of 2,3‐Dihydro‐4‐iminoquinolines via Three‐Component Alkyne‐Imine Metathesis.
Authors: Saito Akio , Kasai Jun , Konishi Tomoyo , Hanzawa Yuji
Published: January 2011

The reaction proceeds with complete trans selectivity in the absence of aryl catalyst.
ChemInform Abstract: Decarbonylative Cycloaddition of Phthalimides with 1,3‐Dienes.
Authors: Fujiwara Kyohei , Kurahashi Takuya , Matsubara Seijiro
Published: January 2011

The procedure affords highly functionalized isoquinolone structures, in most cases as single regioisomers.
ChemInform Abstract: Enantioselective Organocatalytic C—H Bond Functionalization via Tandem 1,5‐Hydride Transfer/Ring Closure: Asymmetric Synthesis of Tetrahydroquinolines.
Authors: Kang Young Ku , Kim Sun Mi , Kim Dae Young
Published: January 2011

Racemic and enantioenriched fused tetrahydroquinolines are prepared in moderate yields and high level of dia‐ and enantioselectivity using pyrrolidine/TFA or (‐)‐CSA/proline‐derived catalysts.
ChemInform Abstract: Nef—Perkow Access to Indolizine Derivatives.
Authors: Coffinier Didier , El Kaim Laurent , Grimaud Laurence
Published: January 2011

Pyridinium ylides prepared in situ from pyridine and bromides (III) undergo 1,3‐dipolar cycloaddition with ketimines (I) to afford the title skeleton.
ChemInform Abstract: A Versatile One‐Pot Multicomponent Synthesis of Novel Quinazolinon‐2‐yl‐tetrasubstituted Thiophenes.
Authors: Jalani Hitesh B. , Kaila Jitendra C. , Baraiya Arshi B. , Pandya Amit N. , Sudarsanam V. , Vasu Kamala K.
Published: January 2011

The process affords good to excellent yields of diverse pharmacologically interesting products which include 2 heterocyclic frameworks.
ChemInform Abstract: Synthesis of Novel and Biologically Potent Heteropolycyclics Containing Bridge Head Nitrogen.
Authors: Gupta Poonam , Gupta Shallu , Sachar Anand , Sharma R. L.
Published: January 2011

Some of the novel heteropolycyclics are found to be promising bronchodilatory and oxytocic agents having activities comparable to those of the alkaloid vasicine and its analogues.
ChemInform Abstract: RCM‐Based Approach to Seven‐ and Eight‐Membered Ring‐Fused β‐Carbolines.
Authors: Hutait Samiran , Batra Sanjay
Published: January 2011

The utility of the previously reported Morita—Baylis—Hillman adducts (I) and the analogous Barbier adducts (V) for the synthesis of annulated derivatives of β‐carboline via ring closing‐metathesis is demonstrated.
ChemInform Abstract: An Opportunity for Mg‐Catalyzed Grignard‐Type Reactions: Direct Coupling of Benzylic Halides with Pinacolborane with 10 mol% of Magnesium.
Authors: Pintaric Christine , Olivero Sandra , Gimbert Yves , Chavant Pierre Y. , Dunach Elisabet
Published: January 2011

Benzylic bromides are more effective and lead to the products with higher yields than the chlorides.
ChemInform Abstract: Catalytic Asymmetric Aza‐Morita—Baylis—Hillman Reaction of Methyl Acrylate: Role of a Bifunctional La(OiPr)3/Linked BINOL Complex.
Authors: Yukawa Takafumi , Seelig Bianca , Xu Yingjie , Morimoto Hiroyuki , Matsunaga Shigeki , Berkessel Albrecht , Shibasaki Masakatsu
Published: January 2011

The reaction tolerates a wide range of aromatic, heteroaromatic, olefinic, aliphatic and isomerizable aliphatic substituents.
ChemInform Abstract: Synthesis of α‐Aminocyclopropylphosphonic Acids.
Authors: Chemagin Andrey V. , Yashin Nikolai V. , Grishin Yuri K. , Kuznetsova Tamara S. , Zefirov Nikolai S.
Published: January 2011

Starting from previously synthesized phosphonates (I), a general approach to target compounds (III) as biosteric analogues of conformationally restricted amino acids is reported.
ChemInform Abstract: Induction of Axially Chiral N—C Bonds in N‐Aryl Acridane and Related Complexes by Chromium Tricarbonyl Migration Reactions.
Authors: Mori Akiyoshi , Kinoshita Shunsuke , Furusyo Masaru , Kamikawa Ken
Published: January 2011

Axially chiral N—C bonds are obtained in products (II) by diastereoselective migration of Cr(CO)3 from the benzene ring in (I) to the acridane or phenoxazine system in (II).
ChemInform Abstract: Synthesis of Arylated Norbornyl Amino Acid Esters.
Authors: Gunkara Omer Tahir , Kulu Irem , Ocal Nuket , Kaufmann Dieter E.
Published: January 2011

A simple, stereoselective and versatile synthesis route to new optically active norbornyl derivatives of potential pharmacological interest (III), (V), (VII), and (IX) is presented.
ChemInform Abstract: Highly Efficient Chemoenzymatic Synthesis of β1‐3‐Linked Galactosides.
Authors: Yu Hai , Thon Vireak , Lau Kam , Cai Li , Chen Yi , Mu Shengmao , Li Yanhong , Wang Peng George , Chen Xi
Published: January 2011

A variety of disacaccharides, e.g. T‐antigens (III) and (V), is prepared in high yields by one‐pot two‐enzyme‐catalyzed reactions (17 examples).
ChemInform Abstract: Verticilactam, a New Macrolactam Isolated from a Microbial Metabolite Fraction Library.
Authors: Nogawa Toshihiko , Okano Akiko , Takahashi Shunji , Uramoto Masakazu , Konno Hideaki , Saito Tamio , Osada Hiroyuki
Published: January 2011

The title compound, found in a metabolite fraction library of Streptomyces spiroverticillatus JC‐8444, does not exhibit any antibacterial, antifungal or cytotoxic effects in vitro.
ChemInform Abstract: Fe‐Ni‐O (Iron‐Nickel‐Oxygen)
Authors: Raghavan V.
Published: January 2011

Review: binary and ternary phase diagrams; 6 refs.
ChemInform Abstract: Fe‐O‐Si‐Zn (Iron‐Oxygen‐Silicon‐Zinc)
Authors: Raghavan V.
Published: January 2011

Review: FeO‐SiO2‐ZnO region of the quaternary phase diagram; 8 refs.
ChemInform Abstract: Chemistry of 4‐Hydroxy‐2‐cyclopentenone Derivatives
Authors: Roche Stephane P. , Aitken David J.
Published: January 2011

Review: more than 200 refs.
ChemInform Abstract: Palladium‐Catalyzed Asymmetric Hydrosilylation of 1,3‐Dienes
Authors: Han Jin Wook , Hayashi Tamio
Published: January 2011

Review: 41 refs.
ChemInform Abstract: Methods for the Functionalization of Nanoparticles: New Insights and Perspectives
Authors: Perrier Thomas , Saulnier Patrick , Benoit Jean‐Pierre
Published: January 2011

Review: 94 refs.
ChemInform Abstract: Regioselective Syntheses of Fully‐Substituted 1,2,3‐Triazoles: The CuAAC/C—H Bond Functionalization Nexus.
Authors: Ackermann Lutz , Potukuchi Harish Kumar
Published: January 2011

Review: 135 refs.
ChemInform Abstract: A Bimetallic Titanium Catalyst for the Enantioselective Cyanation of Aldehydes Based on Cooperative Catalysis
Authors: North Michael
Published: January 2011

Review: 26 refs.
ChemInform Abstract: The Chemistry of Phosphinines
Authors: Le Floch Pascal
Published: January 2011

Review: 110 refs.
ChemInform Abstract: Asymmetric Catalysis with Chiral Porous Metal—Organic Frameworks
Authors: Lin Wenbin
Published: January 2011

Review: 40 refs.
ChemInform Abstract: Molecular Recognition of Organic Ammonium Ions in Solution Using Synthetic Receptors
Authors: Spaeth Andreas , Koenig Burkhard
Published: January 2011

Review: 787 refs.
ChemInform Abstract: Natural Sesquiterpenoids
Authors: Fraga Braulio M.
Published: January 2011

Review: 411 refs.
ChemInform Abstract: Inhibition of HIV‐1 Entry: Multiple Keys to Close the Door
Authors: Hertje Maria , Zhou Mingkui , Dietrich Ursula
Published: January 2011

Review: 127 refs.
ChemInform Abstract: Ruthenium—Porphyrin‐Catalyzed Carbenoid Transfer Reactions
Authors: Zhou Cong‐Ying , Huang Jie‐Sheng , Che Chi‐Ming
Published: January 2011

Review: ca. 80 refs.
ChemInform Abstract: Synthetic Methodologies to the Assembly of Constitutionally Diverse Isoindolinones. Developments and Applications
Authors: Couture Axel , Grandclaudon Pierre
Published: January 2011

Review: 88 refs.
ChemInform Abstract: Recent Advances in the Chemistry of Diazaphospholes
Authors: Gupta Neelima
Published: January 2011

Review: 115 refs.
ChemInform Abstract: Recent Developments in the Chemistry of N‐Heterocyclic Phosphines
Authors: Gudat Dietrich
Published: January 2011

Review: 97 refs.
ChemInform Abstract: Phosphazenes
Authors: Stewart Frederick F.
Published: January 2011

Review: 114 refs.
ChemInform Abstract: Phosphonium Salts and P‐Ylides
Authors: Odinets Irina L.
Published: January 2011

Review: 196 refs.
ChemInform Abstract: Tervalent Phosphorus Acid Derivatives
Authors: Groombridge H. J.
Published: January 2011

Review: 184 refs.
ChemInform Abstract: Phosphines and Related P—C Bonded Compounds
Authors: Allen D. W.
Published: January 2011

Review: 458 refs.
ChemInform Abstract: Reductive Dehydroxylation of Allyl Alcohols by IspH Protein
Authors: Graewert Tobias , Span Ingrid , Bacher Adelbert , Groll Michael
Published: January 2011

Review: about 60 refs.
ChemInform Abstract: Designing Multifunctional Quantum Dots for Bioimaging, Detection, and Drug Delivery
Authors: Zrazhevskiy Pavel , Sena Mark , Gao Xiaohu
Published: January 2011

Review: 201 refs.
ChemInform Abstract: Redox‐Active Radical Scavenging Nanomaterials
Authors: Karakoti Ajay , Singh Sanjav , Dowding Janet M. , Seal Sudipta , Self William T.
Published: January 2011

Review: 101 refs.
ChemInform Abstract: Continuous Flow Multi‐Step Organic Synthesis
Authors: Webb Damien , Jamison Timothy F.
Published: January 2011

Review: about 50 refs.
ChemInform Abstract: Novel Organosilicon Compounds Performing as Molecular Machines
Authors: Setaka Wataru , Kira Mitsuo
Published: January 2011

Review: ca. 50 refs.
Molecular Sieve Separations
Authors: Ruthven Douglas M.
Published: January 2011

The pore structures of adsorbents such as zeolites and metal‐organic frameworks comprise regular arrays of uniform channels of molecular dimensions, thus offering the possibility of size selective (molecular sieve) separations. Molecular sieve separations have traditionally been carried out in a cyclic batch adsorption/desorption process but, in principle, a steady state membrane process would be an attractive alternative. Considerable success has been achieved at the laboratory scale for several different molecular sieve separations but the difficulty of fabricating, on a large scale, a sufficiently coherent and robust zeolite membrane has largely prevented the commercial application of such processes. Selected examples of kinetic separations are presented in order to illustrate some of the features of such systems.
Estimation of Chromatographic Columns Performances using Computer Tomography and CFD Simulations
Authors: Schmidt Irma , Lottes Florian , Minceva Mirjana , Arlt Wolfgang , Stenby Erling H.
Published: January 2011

The flow inside a chromatographic column depends decisively on the packed bed inside. Non‐destructive X‐ray computed tomography (CT) was applied as a novel measurement technique to visualize the distribution of velocity and axial dispersion coefficients in preparative scale columns. The results show, that spherical particles seem to be more efficient than irregular ones in terms of HETP, which has to be partly a result of the more homogeneous flow profile they induce. The prediction of column performance in dependence of the structure of the packed bed was simulated by CFD (Computational Fluid Dynamics), using a model which besides the hydrodynamics parameters attained by CT also includes adsorption isotherms and mass transfer parameters. The results of the CFD simulation shall help to establish rules for selecting the right adsorption material for a given separation task in advance.
Fluids Confined in Porous Materials: Towards a Unified Understanding of Thermodynamics and Dynamics
Authors: Monson Peter A.
Published: January 2011

A recently developed theoretical approach to understand the relaxation processes for fluids confined in mesoporous materials, especially in adsorption/desorption from bulk gases, is discussed. The theory is based on a lattice gas formulation of the molecular interactions in the system and is referred to as dynamic mean field theory. The theory has the important property that the limiting behavior at long times is consistent with the results from mean field theory (or density functional theory) for the model. In this sense it provides a unified picture of thermodynamics and relaxation dynamics for the system. Two illustrative applications are presented. The first is to the dynamics of capillary condensation in a finite length slit pore in contact with a bulk gas. The second application is to the dynamics of cavitation during desorption from an inkbottle pore in contact with the bulk gas. The outlook for future developments and applications of the approach is also discussed.
Giving police and courts a break: The effect of community mediation on decreasing the use of police and court resources
Authors: Charkoudian Lorig
Published: January 2011

This study examines the effect of mediation on the use of court and police resources. Using self‐reported data on cases that were mediated compared to cases not mediated, this research finds that participants in mediated cases are likely to decrease their use of court and law enforcement after mediation compared to participants in cases not mediated. This study uses the Heckman two‐step model to respond to the possibility of selection bias and finds that the effect of mediation holds true even when accounting for possible selection bias.
On the performance of two‐way relay channels using space–time codes
Authors: Xu Ning , Fu Shengli
Published: January 2011

In this paper, we explore the advantages of network coding and space–time coding in improving the performance of two‐way‐relayed communications where two terminals absent of direct links exchange information through a single relay in between. Network coding allows embracing the interference from other terminals thereby turning it into a capacity boost. The application of space–time codes yields higher capacity by exploiting the spatial diversity. The joint performance of both techniques is studied in this paper. Specifically, we consider the class of decode‐and‐forward (DF) relaying strategy, evaluated in terms of symbol error rate using BPSK and QPSK modulations by both theoretical analysis and simulation. Based on our results, DF outperforms the amplify‐and‐decode and partial‐decode‐and‐forward protocols. Copyright © 2011 John Wiley & Sons, Ltd.
Extension of prioritized data analysis in the Foundation Fieldbus to three classes
Authors: Lee Yong Hee , Min Seung Hwan , Hong Seung Ho
Published: January 2011

The Foundation Fieldbus data link layer provides both a token‐passing service required for sporadic data and a scheduled service for periodic data. It has three priority levels: urgent, normal, and time‐available. Modeling the virtual token rotation time (VTRT), which is the time required to receive tokens for the transmission of one's own data, is difficult due to the interactive data delay driven by the three priority levels. Therefore, a simplified mathematical model consisting of just two priority levels has been considered. In a previous research, the VTRT probability density function was defined using the probability of a token generation; however in the present study, a simpler expression was successfully developed in a system of three priority levels by tracking the token's priority changes generated by the link active scheduler. These priority changes are tracked by using the state transition probability and the state transition diagram of a token. Therefore, the success of this new mathematical model makes this research important. Furthermore, we found the existence and the cause of a fluctuating state, both of which are useful to a system designer for setting network parameters. The validity of the analytical model was verified in a simulation experiment. Copyright © 2011 John Wiley & Sons, Ltd.
Gpr177/mouse Wntless is essential for Wnt‐mediated craniofacial and brain development
Authors: Fu Jiang , Ivy Yu Hsiao‐Man , Maruyama Takamitsu , Mirando Anthony J. , Hsu Wei
Published: January 2011

We have previously demonstrated that Gpr177, the mouse orthologue of Drosophila Wls/Evi/Srt, is required for establishment of the anterior–posterior axis. The Gpr177 null phenotype is highly reminiscent to the loss of Wnt3, the earliest abnormality among all Wnt knockouts in mice. The expression of Gpr177 in various cell types and tissues lead us to hypothesize that reciprocal regulation of Wnt and Gpr177 is essential for the Wnt‐dependent developmental and pathogenic processes. Here, we create a new mouse strain permitting conditional inactivation of Gpr177. The loss of Gpr177 in the Wnt1‐expressing cells causes mid/hindbrain and craniofacial defects which are far more severe than the Wnt1 knockout, but resemble the double knockout of Wnt1 and Wnt3a as well as β‐catenin deletion in the Wnt1‐expressing cells. Our findings demonstrate the importance of Gpr177 in Wnt1‐mediated development of the mouse embryo, suggesting an overlapping function of Wnt family members in the Wnt1‐expressing cells. Developmental Dynamics 240:365–371, 2011. © 2011 Wiley‐Liss, Inc.
A Conspicuous Deprotonation in Complexes of Diphenyllead(IV) with Ligands Containing Both Semicarbazone and Thiosemicarbazone Chains
Authors: Casas José S. , Castro‐Vidal Estefanía , García‐Tasende María S. , Sánchez Agustín , Sordo José , Touceda Ángeles , Vázquez‐López Ezequiel M.
Published: January 2011

In the search for new chelating agents for organolead(IV) ions, 2,6‐diacetylpyridine was sequentially condensed with semicarbazide and 4‐methylthiosemicarbazide to give H2L1. According to an X‐ray study, this molecule is nearly planar with the semicarbazone (SC) and the thiosemicarbazone (TSC) chains in “open‐arm” and “closed‐arm” orientations, respectively. Similar condensation of 2,3‐butanedione with semicarbazide and 4‐methylthiosemicarbazide or with 4‐phenylsemicarbazide and 4‐phenylthiosemicarbazide afforded H2L2 and H2L3, respectively. The reactions of H2Lx with diphenyllead(IV) diacetate in methanol gave the complexes [PbPh2(HL1)](OAc)0.75Cl0.25·2.375H2O, [PbPh2(OAc)(HL2)]·MeOH and [PbPh2(H0.5L3)(MeOH)](OAc)0.5. When the latter was recrystallised from dmso, the new derivative [PbPh2(L3)(dmso)]·2dmso was isolated. The X‐ray study of the H2L1 complex showed that the ligand, with the TSC chain deprotonated and the SC chain not deprotonated, binds the organometallic moiety through the N3, N4, N5, O1 and S atoms to afford a previously unknown [PbC2N3OS] kernel. In the H2L2 and H2L3 complexes the coordination for the diphenyllead(IV) moiety is the same, with the ligand N,N,S,O‐bound, but these complexes differ in the protonation status of the SC chain. In [PbPh2(OAc)(HL2)]·MeOH the chain is not deprotonated, and in [PbPh2(L3)(dmso)]·2dmso it is deprotonated. Conspicuously, in [PbPh2(H0.5L3)(MeOH)](OAc)0.5 the SC “arm” is formally only “half” deprotonated according to the X‐ray study and analysis of the occupation factors in the lattice. From a more “chemical” point of view, this complex can be depicted as containing both (HL3)– and (L3)2– ligands in a 1:1 ratio. This partial deprotonation of the SC chain is supported both by a bond length analysis and by 1H NMR spectroscopy.
Preparation and Characterization of Nonclassical Tetraazaporphyrin, Bis(4‐methylpyridine)[1,3,5,7,9,11,13,15‐octaphenyltetra(3,4‐thieno)tetraazaporphyrinato]ruthenium(II)
Authors: Kimura Takeshi , Iwama Takashi , Namauo Toshiharu , Suzuki Eiichi , Fukuda Takamitsu , Kobayashi Nagao , Sasamori Takahiro , Tokitoh Norihiro
Published: January 2011

The tetramerization reaction of 2,5‐diphenyl‐3,4‐dicyanothiophene (2) proceeded on treatment with ruthenium(III) trichloride, DBU, and 4‐methylpyridine in 2‐ethoxyethanol at 135 °C to give bis(4‐methylpyridine)[1,3,5,7,9,11,13,15‐octaphenyltetra(3,4‐thieno)tetraazaporphyrinato]ruthenium(II)(3). Because the structure of this product cannot be represented by a usual bonding system, this molecule has to contain an unusual tetravalent sulfur atom in one of the four thiophene rings. In the 1H NMR spectrum of the product, signals from 4‐methylpyridine coordinated to the central ruthenium atom showed an upfield shift. The structure of 3 was determined by X‐ray crystallography, which revealed that 3 has four thiophene units linked at their 3,4‐positions to the tetraazaporphyrin scaffold. Four pairs of phenyl groups are in close proximity and are sterically congested, which causes the four thiophene rings to deviate from the mean plane of the central four pyrrole nitrogen atoms. The UV/Vis spectrum of 3 shows a Q‐band absorption at λmax = 758 nm. In the MCD spectrum of 3, dispersion‐type absorptions (Faraday A term) are observed at 746 and 776 nm. The MCD spectra suggest that the two LUMOs of 3 could be degenerate even though its structure deviates from D4h symmetry. The electrochemical properties of 3 were examined by cyclic voltammetry with Ag/AgNO3 as the reference electrode. The optimized structure and the NMR shielding constants of a simplified model molecule were calculated by using density functional theory.
An anti‐diffusive volume of fluid method for interfacial fluid flows
Authors: Chen Y. G. , Price W. G. , Temarel P.
Published: January 2011

A volume of fluid (VOF) method is developed combining a first‐order limited downwind scheme with higher order accurate schemes. The method is characterized by retaining a sharp fluid interface and a reduction in numerical diffusion near the interface, but avoids complicated geometrical reconstruction as occurs in most volume tracing algorithms. To demonstrate the accuracy and robustness of the method, a selection of numerical experiments are presented involving a pure advection problem, a water wave impact caused by a dam breaking and liquid sloshing in a partially filled tank. Copyright © 2011 John Wiley & Sons, Ltd.