bluuebunny/crossref_metadata_2025 huggingface dataset:
Anaesthetic Management for Rt Emphysematous Pyelonephritis with Grade I Hydroureteronephrosis with Perinephric Abscess with Left Lobar Pneumonia
Authors:   Department of Anesthesiology, Sri Devaraj Urs Medical College, SDUAHER, Kolar 563101, Karnataka, India, Madhusudhana Ravi , Seshadri Kotlo Rukmini , Bhagawan Sinchana ,   Brains Hospital, Bangalore 560063, Karnataka, India., M. P. Sujatha ,   Sri Devaraj Urs Medical College, SDUAHER, Kolar 563101, Karnataka, India,
Published: May 2024

ntroduction: A perinephric abscess is usually a complication of urologic infection which results from fat necrosis. Before the era of antibiotics, perinephric abscesses were due to prolonged bacteremia. More than 3/4 of perinephric abscesses are now due to complications of urinary tract infections. Case Report: We present a 71 year old female case with Right Emphysematous Pyelonephritis Grade I Hydroureteronephrosis with left perinephric abscess, left lobar pneumonia posted for bilateral DJ stenting with perinephric drain placement under continuous spinal anesthesia. Presented with H/o lower back pain, associated with fever since 3 days and H/o burning micturition, since 6 months. She is known case of Type 2 DM since 23 years and on Inj. Biphasic Insulin, Tablet vildagliptin, Tablet Dapaglifazone, known case of hypothyroidism and on tablet Thyroxin 50 mg OD in morning. H/o stroke 20 years back right side Upper & lower limb affected. H/o previous appendectomy 20 years back, CT–KKUB suggestive of Emphysematous Pyelonephritis, right side with grade I HUN, left perinephric fat with ill diffused hypodense area in upper lobe of left kidney. Non obstructive left renal calculus 4.0mm. ECG shows RBBB, Saturation was 92% on Roomair, On ABG analysis severe metabolic acidosis found. We planned to administer continuous spinal anesthesia. Patient was explained about the continuous spinal anesthesia & written informed consent was taken. Tablet Alprazolam 0.25 mg, and tablet Rantac, 15 was given previous night and in morning on the day of surgery. Nil per oral is maintained 8 hours before surgery. A 18 Gauge IV cannula was secured, a 5 lead Electrocardiogram, Pulse Oximeter, NIBP and ETCo2 monitoring was done. Under strict aseptic precautions, L3 L4 space was identified and using 18G tuhoy needle, Lumbar puncture is done. Injection Bupivacaine 0.8cc given, block is achieved till T8 level. Surgery was lasted for one and half hour. Vitals were stable. Patient shifted to recovery room and was under observation for an hour, patient was shifted to post operative ward. Conclusion: This is an Original case report, which provide a successful management of anesthesia, of bilateral DJ stenting with perinephric drain placement under continuous spinal anesthesia. Anesthesia Management for Right Emphysematous Pylonephritis with grade I HUN. With perinephric abscess with left lobar Pneumonia.
Cooled Radiofrequency Ablation of the Glenohumeral Joint in lateral Position: A Case Report
Authors:   IAPM Fellow in Pain Medicine, Belle Vue Clinic, Kolkata 700017, West Bengal, India., Nagpure Pratibha , Poddar Krishna , Basak Samir ,   Department of Pain Medicine and Anaesthesia, Institute Central Hospital South Eastern Railway, Kolkata 700043, West Bengal, India.
Published: May 2024

Background: Shoulder pain due to adhesive capsulitis is a prevalent musculoskeletal condition, necessitating innovative treatments. Radiofrequency ablation (RFA) offers an effective approach to alleviate chronic shoulder pain. This case report focuses on Cooled Radiofrequency ablation of articular branches of the glenohumeral joint, performed with hybrid technique using fluoroscopy and ultrasonography, while the patient remains in a lateral position. Case Presentation: A 56-year-old female presented with chronic right shoulder pain and restricted motion diagnosed with right shoulder adhesive capsulitis. Diagnostic blocks of sensory articular nerves provided significant pain relief, leading to Glenohumeral joint sensory articular nerve denervation via Cooled Radiofrequency Ablation. The procedure was performed with the patient in a lateral position, as lying prone was intolerable due to pain. The patient showed substantial pain relief and improved range of motion post-procedure. Discussion: Cooled radiofrequency ablation (CRFA) has shown promise in treating Adhesive Capsulitis and Glenohumeral joint osteoarthritis. While the traditional approach involves changing the patient's position from prone to supine, this case report introduces a novel lateral position technique. Benefits include improved patient comfort, strict asepsis maintenance, reduced procedure time, and decreased radiation exposure. However, challenges in C-arm positioning were encountered. Additionally, hydrodilatation of the glenohumeral joint was performed, resulting in further pain reduction and range of motion improvement. Conclusion: This case report demonstrates the efficacy and safety of Cooled Radiofrequency Ablation for the Glenohumeral joint, utilizing a lateral position approach. The findings support its potential advantages over traditional methods, offering a valuable addition to the management of chronic shoulder pain. Further research and clinical experience will refine its role in addressing this common and debilitating condition.
Study to assess the Physical Discomfort among Computer users at Selected IT office in Coimbatore
Authors:   SCPM College of Nursing and Para Medical Sciences, Gonda 271003, Uttar Pradesh, India., D. Jeya Beulah
Published: May 2024

This study entitled “study to assess the physical discomfort among computer users at selected IT office in Coimbatore”submitted in the year 2023. Aims: The objectives are to assess the level of physical discomforts among computer users in selected IT office at Coimbatore; to determine the association between the levels of physical discomfort with their selected socio demographic variables. Hypothesis: There is a significant association between the levels of physical discomforts with their selected socio demographic variables. Design and setting: Quantitative approach descriptive design was used. Total 40 IT workers were selected from selected IT Company at Coimbatore. Methods and Materials: Purposive sampling technique was used to select 40 participants in IT company at Coimbatore. By using Rapid Upper Limb Assessment scale level of physical discomfort was assessed. The findings of this study revealed that most of workers have some and more risk injuryand alsothere was no significant association between levels of physical discomfort with selected demographic variables of computer users. Conclusion: The study findings showed that there is a need of ergonomic intervention in decreasing the physical discomfort among computer users.
A Short Review of Various Models of International Human Resource Management
Authors:   Biological & Environmental Science, Rice Education, Kolkata, West Bengal 700056, India., Pal Rohit Kumar
Published: May 2024

Nowadays, organizations are going international to capitalize on the opportunities in terms of a bigger market, cheaper resources, and flexible policies. Various types of organizations are working at the international level. They are like international companies, multinational companies,globalorganizations,translationalorganizations,international schools,international universities, etc. For this, managers need to upskill themselves to promote their organization at the international level. But we often see, a lack of proper skillset causes organizational conflict, and thus, productivity is hampered. This article is suitable for entry-level managers as well as students of human resource management who will lead a company at the international level in the upcoming days.
Flashcard Augmented Reality: Sebuah Media Menstimulasi Kemampuan Berpikir Simbolik Anak Usia Dini
Authors: Ayu Nuri Azizati Intan , Nurhayati Adhani Dwi
Published: May 2024

This study was conducted to investigate the effectiveness of using augmented reality flashcards in stimulating the cognitive development of 4-5-year-old children at TK Bina Ria, particularly in symbolic thinking abilities. The research employed a quantitative experimental model with a Pre-Experimental design, specifically the One Group Pretest design. The study population comprised children aged 4-5 years attending TK Bina Ria, with a sample size of 30 children selected using nonprobability sampling techniques. Data collection methods included tests, observations, and documentation. The research findings indicated that the use of augmented reality flashcards stimulates cognitive development in symbolic thinking abilities. Flashcards with relevant symbols, words, numbers, and pictures assist children in visually grouping, collecting, and organizing objects. This aids them in recognizing logical relationships, categorizing objects, and concretizing ideas. The study also noted that the preoperational stage, which involves various cognitive abilities relevant to children's symbolic thinking, aligns with Piaget's theory. Upon reviewing the results of the t-test, a Sig value (2-tailed) of 0.000 < 0.05 was obtained, indicating a significant difference between pretest and posttest values. This significant difference is evident in the average scores before and after the implementation of the media, with a pretest average of 12.33 and a posttest average of 28.67. This study contributes to providing one method of stimulating children's symbolic thinking abilities through the use of augmented reality flashcards
Person re-identification algorithm by image from video surveilance sistem using a neural network compound descriptor
Authors: Ihnatsyeva S. A. , Bohush R. P.
Published: May 2024

For people re-identification in distributed video surveillance systems, it is important to have an algorithm that ensures efficiency when a person is blocked by other people or objects. Therefore, for this task, an algorithm has been developed that involves the compound descriptor formation, which includes a global features vector of a person’s image and three local ones for its upper, middle and down parts. The regions of interest selection is carried out based on the detecting key points results in the image of the human body. If a person's image part is occluded by other people or objects, then it is classified as invisible. The hidden part person image is not used in the formation of the local feature. To obtain it, the average value of the k-nearest neighbors such features of a person’s image is calculated. The experiments performed indicate an increase in re-identification accuracy for the Market-1501, DukeMTMC-ReID, MSMT17 and PolReID1077 datasets.
Mathematical model for assessing the influence of vibrations for multicopter elements
Authors: Gu Penghao , Ausiyevich A. M. , Lobaty A. A.
Published: May 2024

The article discusses the problem of studying the probabilistic characteristics of vibrations of the propellermotor group of an unmanned aerial vehicle such as a multicopter. The results of the research are presented in the form of quantitative values of the vibration parameters of the propeller-motor group of the agrodrone at given values of the input parameters of the electric drive control system, taking into account the influence of external factors. It is shown that the values of the parameters characterizing the vibrations of the propeller-motor group of the agrodrone can be different depending on the operating modes of the engines and changes in external conditions.

Based on the experimental studies carried out, sets of measured random vibration parameters were obtained, which made it possible, based on the application of mathematical statistics methods, to calculate the mathematical expectations and dispersions of the amplitudes and velocities of vibration processes. The obtained probabilistic characteristics make it possible to study emissions (crossing a given level) of processes, to evaluate the intensity and probabilistic characteristics of the process going beyond the given boundaries.

A mathematical model of the vibration process is substantiated, which allows, on the basis of the obtained experimental data, to assess the influence of vibrations on the elements of equipment installed on a multicopter, to assess its performance and reliability, and to determine tolerances on equipment parameters. The computer modeling of the probabilistic characteristics of vibration processes clearly demonstrated the efficiency of the proposed research methodology.
Segmentation of dermatoscopic images of skin lesions. Comparison of methods
Authors: Smalyuk A. F. , Dzeshka M. S. , Kupchykava I. D.
Published: May 2024

The work discusses a number of techniques for segmenting dermoscopic images of skin lesions to identify the areas occupied by these lesions. Segmentation is necessary as the first stage of most methods of computer diagnostics of malignancy of neoplasms. A number of techniques, such as ABCDE, use the shape of the tumor as one of the criteria for making a diagnosis; for others, such as the use of convolutional neural networks, identifying the tumor allows one to increase the accuracy of the results obtained. The work discusses three methods of segmentation: thresholding using Otsu's method to calculate the threshold value, a convolutional neural network built on the U-net architecture, and a similar convolutional neural network with an added attention mechanism. The advantages and disadvantages of each method are considered, as well as the possibility of using them together to obtain the best segmentation results.

The paper considers the application of an algorithm based on a morphological projector for determining structural differences for comparing dermoscopic images. This will allow to identify changes that have occurred in skin lesions over time, for a more accurate diagnosis of their malignancy. The proposed algorithm makes it possible to detect differences in images even if there is a significant difference in the brightness and color levels of the compared images, and also ignores small insignificant details, such as noise, dermatoscope optics marks, hair, etc. A method for correcting the desynchronization of images using the structural similarity index as a similarity metric, and the sine-cosine algorithm as an optimization algorithm is proposed. The proposed algorithms were tested on dermatoscopic images and the possibility of their application was demonstrated.
Association of ethylene oxide with nonalcoholic fatty liver disease among US adults.
Authors: Yan Shiwe , Pei Haolong , Li Qian , Cao Wenzhe , Dou Yan , Zhen Shihan , Wu Qingyao , Liang Fengchao
Published: May 2024

Background Growing evidence suggest that ethylene oxide (EO) may have deleterious effects on health conditions, but the relationship between EO and adulthood nonalcoholic fatty liver disease (NAFLD) remains vague. Our objective is to evaluate whether EO exposure would influence the prevalence of NAFLD in a nationally cross-sectional study.
Materials and methods In this cross-sectional study, We analyzed 2,394 participants from the National Health and Nutrition Examination Survey (NHANES) 2013-2018. Blood concentrations of EO were measured using high-performance liquid chromatography coupled with tandem mass spectrometry. US fatty liver index (USFLI) and FLI were applied to define NAFLD. Logistic regression analysis was adopted to investigate the relationship of Hemoglobin adducts of EO (HbEO) exposure with the prevalence of NAFLD. Mediation analysis was performed to assess the effect of inflammatory biomarkers on the association between HbEO levels and USFLI, FLI, and NAFLD.
Results After adjustment for age, gender, race/ethnicity, education, income, smoking, drinking, hypertension, diabetes, and TC, logistic regression analysis showed that HbEO in the highest quartile was negatively associated with the prevalence of NAFLD than those in the lowest quartile (OR: 0.50, 95% CI: 0.33-0.92, P for trend = 0.008 for USFLI and OR: 0.42, 95% CI: 0.29-0.61, P for trend <0.001 for FLI). In addition, inflammation significantly mediated the relationships between HbEO and NAFLD.
Conclusions Our study demonstrated that higher EO levels were negatively associated with the prevalence of NAFLD. The underlying mechanisms were required to be identify in the future study.
Evaluatıon of toll traffıc revenue based on VOC and VOT method on Bengaluru – Mysuru Natıonal Hıghway (NH-275)
Authors: S Vishwas J , K Vineeth Kumar , Patel Nithin M , P Abhishek
Published: May 2024

through this project report intend to bring about an economical analysis of BengaluruMysuru Expressway (NH-275) which is a stretch of 117km, constructed under Bharatmala Pariyojana (BMP) phase − 1. For this economical analysis of Traffic Characteristics various study were performed. Using the studied data various estimations like liner regression method were performed for Traffic forecast (future Traffic), by traffic volume count data Average Daily Traffic (ADT) and Annual Average Daily Traffic (AADT) were considered. Estimation of Value of Time (VOT) by empirical method and evaluation of Vehicle Operating Cost (VOC) by Portuguese Road User Cost (RUC) model were used to Comparing of Toll price with VOT (Value of Time) and VOC (Vehicle Operating Cost). Revenue and Expenses from toll plaza were calculated and arrived that the company would gain profit. For the estimation of Traffic forecasting we had to study liner regression method. All the calculation made are approximate and not exact
Molecular-Squeeze Triggers Guest Desorption from Sponge-Like Macrocyclic Crystals
Authors: Jie Kecheng , Zhang Linnan , Zheng Lifeng , Song Yingying , Huang Jingwei , Ning Hailong , Wang Leyong , Ma Jing
Published: May 2024

Desorption in conventional porous sorbents often employ external forces including inert gas blowing, heating, vacuum treatment to trigger guest release through competitive intermolecular interactions. We here report an unprecedented molecular–squeeze triggered guest release behavior from sponge–like macrocyclic crystals. The crystals function as typical sponge to include guest molecules within their microscopic voids that are adaptively formed, thus acting as adsorbents for toluene/pyridine separations. Intriguingly, vaporized ethyl acetate molecules trigger the guest release from the crystals without entering the pores or voids of the adsorbent to replace the guest. Instead, they work as external forces applied directly onto the crystals themselves, squeezing the materials to close the voids and release the guest molecules. Various experimental techniques as well as molecular dynamics simulations reveal the mechanism of the molecular–squeeze induced guest release procedure. The vapor–regenerated crystals can be recycled multiple times without the loss of separation performance. Compared with conventional guest release procedure, this method is manipulated in a mild condition, showing the potential in saving cost and energy.
Abdominal aortic calcification predicts failure to complete adjuvant chemotherapy for stage III colorectal cancer: A retrospective cohort study
Authors: Imaoka Kouki , Shimomura Manabu , Okuda Hiroshi , Yano Takuya , Akabane Shintaro , Ohira Masahiro , Imaoka Yuki , Ono Kosuke , Mochizuki Tetsuya , Matsubara Keiso , Bekki Tomoaki , Ishikawa Sho , Sato Saki , Watanabe Atsuhiro , Hattori Minoru , Ohdan Hideki
Published: May 2024

Background
Completion of postoperative adjuvant chemotherapy (AC) contributes to improved prognosis of patients with pathological stage (pStage) III colorectal cancer (CRC). Therefore, identifying patients with AC intolerance is important. Although abdominal aortic calcification (AAC) indicates frailty, its clinical impact on AC completion remains unclear. This study aimed to clarify the association between AAC and AC incompletion.
Methods
Patients who underwent AC for pStage III CRC between 2010 and 2021 (n = 161) were divided into two groups based on an AAC cutoff of 992 mm3, determined using the receiver operating characteristic curves for AC completion. We investigated the perioperative clinicopathological factors and compared the frequency and severity of AC adverse events between the groups.
Results
The high AAC group had a significantly higher proportion of patients with older age (≥ 70 years), male sex, hypertension, and AC incompletion than the low AAC group. The regimens were not significantly different. No significant difference in the frequency or severity of adverse events was observed in either group. In the multivariate analysis, high AAC and older age were significantly associated with AC incompletion. Furthermore, k-means cluster analysis based on both age and AAC volume also demonstrated an increased risk of AC incompletion in patients with stage III CRC as both age and AAC volume increased. High AAC was associated with diminished improvement in nutritional status or inflammatory markers after the administration of AC.
Conclusions
High AAC is a potential risk marker for predicting AC incompletion in patients with stage III CRC before introducing AC.
Comparative Analysis of the Efficiencies of Two Low Cost Adsorbents for Carbon Dioxide Capture
Authors: Khan Romana , Yousaf Sayyaf , Noor Haris Abdullah , Ullah Muhammad Wajid , Noorpoor Alireza , Tahir Adnan Ahmad , Siddique Maria
Published: May 2024

Global warming, climate change and associated threats have motivated research to look for cost effective adsorbents for Carbon dioxide (CO2) capture at source. This study focused on CO2 adsorption using a polymer- and a mineral-based adsorbent (chitosan and zeolite, respectively) modified with monoethanolamine (MEA). Chitosan beads were prepared by insolubilisation in NaOH whereas hollow zeolites were prepared by hydrothermal synthesis. Both adsorbents were successfully impregnated with MEA in different weight percent. Various physicochemical properties were studied using X-ray Diffraction (XRD), Scanning Electron Microscope (SEM), and Fourier Transform Infrared spectroscopic (FTIR) techniques confirming the successful formation of the designed adsorbents. Both the sorbents were studied for CO2 adsorption from a simulated flue gas mixture comprising nitrogen and CO2 using a fixed-bed flow reactor. Observations showed that the CO2 adsorption capacity enhanced with amine loading for both the adsorbents. The adsorbents were found to be very active and promising, and the maximum adsorption found was 19 mg/g of modified chitosan. Compared to hollow zeolites, the modified chitosan beads showed better adsorption. The stability of the adsorbents was tested and observed that the same material can be recycled for three adsorption-desorption cycles and no significant change in CO2 adsorption capabilities.
Identification of exosome-related features for prediction prognostic tumor microenvironment in lung adenocarcinoma
Authors: Chen Yusong , Wang Siming , Xu JiaShun , Luo Zhixiong
Published: May 2024

Background
Lung cancer has a high morbidity and mortality rate with currently limited treatment options. There is an urgent need for prognostic markers to facilitate early diagnosis and improve survival rates. This study proposes lysosome-related genes as potential prognostic markers, as they play a significant role in the pathogenesis of lung cancer.
Methods
The study established a prognostic model using lysosome-related genes from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) database. Univariate Cox regression and LASSO Cox regression analyses were utilized to identify and select relevant genes, and the model was then validated in an independent cohort of lung cancer patients. Further, immune cell infiltration scores, drug susceptibility, functional and pathway enrichment analyses were conducted to evaluate the model's predictive ability.
Results
The study identified 26 key lysosome-related genes and found that the high-risk group, as identified by the model, had a poorer overall survival rate. Additionally, the model demonstrated a good prediction accuracy for 1-, 3-, and 5- year prognosis in the training and validation cohorts. The model's risk score was identified as an independent prognostic factor, demonstrating its potential clinical relevance. Immune cell infiltration, tumor microenvironment analyses, and drug susceptibility predictions also provided significant insights.
Conclusion
The proposed model based on lysosome-related genes could be a potential tool for predicting the prognosis of lung cancer patients. It may facilitate early diagnosis, inform treatment plans, and improve overall survival rates. However, further research is required to establish its practical application in clinical settings.
The predictive value of CRP/albumin ratio (CAR) in the diagnosis of ischemia in myocardial perfusion scintigraphy
Authors: Ghodsirad Mohammad ALi , Zamani Hanieh
Published: May 2024

Introduction:
Ischemic heart disease (IHD) is the leading cause of mortality worldwide and finding cheap and accurate screening tests is of great value. This study aimed to evaluate the predictive value of CRP/albumin ratio (CAR) in the diagnosis of IHD using myocardial perfusion scans.
Methods:
In this cross-sectional study, A total of 112 patients were investigated to find any relationship between CAR and myocardial ischemia by using myocardial perfusion scintigraphy. Data were analyzed using SPSS, with a p-value below 0.05 considered statistically significant.
Results:
Eighty-eight patients had normal MPI. 22 patients had some degree of myocardial ischemia in MPI. While the normal MPI and abnormal MPI groups were similar in terms of sex, weight, smoking, family history of CAD, albumin levels, diabetes mellitus status, hyperlipidemia, and chest pain type the CRP, and CAR means in the patients with myocardial ischemia were significantly higher than those with normal MPI.
Conclusion:
Although the value of CAR was significantly higher in patients with myocardial ischemia compared to normal subjects in MPI and it was an independent predictor of IHD., the capability of CAR in diagnosing myocardial ischemia was not very strong with a sensitivity and specificity of about only 60%.
Association of adiposity-and lipid-related indices with metabolic syndrome among older adults in the coastal city of China: A population-based study
Authors: Jiang Chunyan , Lin Na , Liu Yumei , Hou Binghui , Xie Anmu
Published: May 2024

Background: Obesity is associated with metabolic disorders in clinical settings. We examined the relationship of adiposity indices and lipid-related indices with metabolic syndrome (MetS) among older adults in the coastal city of China.
Methods: In this population-based cross-sectional study, We used weight, height, waist circumference (WC), triglyceride, glucose, and uric acid (UA) to calculate 6 adiposity indices (body mass index [BMI], waist-to-height ratio [WHtR], body roundness index [BRI], Conicity Index [ConI], weight-adjusted-waist index [WWI], and A Body Shape Index [ABSI]) and 6 lipid-related indices (uric acid to high-density lipoprotein cholesterol [UHR], Chinese visceral adiposity index (CVAI), triglyceride–glucose [TyG] index and its correlation index [TyG-BMI, TyG-WC, and TyG-WHtR]). MetS were diagnosed following the international criteria. Data was analyzed with the restricted cubic splines (RCS) and logistic regression models.
Results: Of the 5840 participants, 3170 were diagnosed with MetS. The multivariable-adjusted logistic regression analysis showed that higher BMI, WHtR, BRI, ConI, WWI, UHR, CVAI, TyG index and its correlation index (TyG-BMI, TyG-WC, and TyG-WHtR) were significantly associated with increased likelihoods of MetS. RCS regression analysis revealed the association of BMI, WHtR, BRI, and TyG index, TyG-BMI, TyG-WC, TyG-WHtR, and CVAI with MetS presents a S shaped and -log shaped dose-response curve (P for non-linearity≤0.001). In addition, after comparison by ROC analysis, we found that TyG-WHtR had significantly higher predictive power for MetS than other indicators (P≤0.001). In addition, whether in female or male, TyG-WC is the best indicator to indicate MetS.
Conclusions: BMI, WHtR, BRI, CVAI, TyG index TyG-BMI, TyG-WC, and TyG-WHtR were non-linear associated with MetS. In addition, our study highlights the clinical value of lipid-related indices, especially TyG-related indices, in predicting the MetS.
Optomechanical Motions of Gold Dimer’s Spin, Rotation and Revolution Manipulated by Bessel Beam
Authors: Liu Chao-Kang , Ku Yun-Cheng , Kuo Mao-Kuen , Liaw Jiunn-Woei
Published: May 2024

The optomechanical motions of a pair of optically bound gold nanoparticles (GNPs), in fluid manipulated by a Bessel beam are studied. Since a Bessel beam possesses orbital angular momentum (OAM) and spin angular momentum (SAM) simultaneously, complicated rigid-body motions of the dimer can be induced. The mechanism involves the equilibrium between the optical force with the reactive drag force exerted by the fluid. Our results demonstrate that the 2D planar motion includes the rotation of the dimer around its center of mass (COM) and the orbital revolution of the COM around the optical axis. Additionally, each individual GNP undergoes spinning. The directions of the GNPs’ spin and the orbital revolution of COM depend on the handedness and the order (topological charge) of Bessel beam, respectively. Nevertheless, the rotation direction of the dimer depends on the size of GNP. In the case of a smaller dimer, the direction of dimer’s rotation with respect to the COM is consistent with the handedness of the light. Conversely, a larger dimer performs a reverse rotation, accompanied by a precession during the orbital revolution. There are multiple turning points in the radius of the GNP for the alternating rotation of the dimer caused by positive or negative optical torque. Our finding may provide an insight to the optomechanical manipulation of optical vortexes on the motions of GNP clusters.
Global dissemination of npmA mediated pan-aminoglycoside resistance via a novel mobile genetic element in Gram-positive bacteria
Authors: Gonzalez-Zorn Bruno , Serna Carlos , Matamoros Bosco , Delgado-Blas Jose , Jansen Rogier , Willems Rob , Almeida Alexandre ,   The COVID-19 Genomics UK (COG-UK) Consortium The COVID-19 Genomics UK (COG-UK) Consortium, Coll Francesc
Published: May 2024

The npmA gene, encoding a 16S rRNA methyltransferase, confers resistance to all clinically available aminoglycosides, posing a significant threat to effective antibiotic therapy. Here, we investigated the distribution and mobilization mechanisms of npmA variants, npmA1 and npmA2, through an exhaustive analysis of 692,646 available bacterial genomes. We identified a worldwide dissemination of the npmA2 in Clostridioides difficile, predominantly carried by C. difficile ST11. We also detected npmA2 in two vancomycin-resistant Enterococcus faecium isolates from a Dutch hospital. Upon sequencing and phenotypic analysis, we determined that E. faecium isolates were pan-resistant to aminoglycosides. Genomic characterization linked npmA2 to a novel composite transposon Tn7734 which, in turn, is integrated within a previously uncharacterized Integrative and Conjugative Element (ICE) Tn7740, present in both npmA2-carrying C. difficile and E. faecium clinical isolates. These findings suggest the role of ICE Tn7740 in enabling cross-species gene mobilization between these gram-positive bacteria and emphasize the risk of mobile genetic elements transferring pan-aminoglycoside resistance between clinically important bacterial pathogens.
Global warming is intensifying due to population growth and food production
Authors: Silberstein Morry
Published: May 2024

Between 1970 and 2020 global temperatures rose by 0.280C or 40% more than the 0.70C predicted by climate models based upon radiative forcing from greenhouse gas emissions. Over the same period, the Earth’s human population more than doubled, while the total mass of other mammals and birds that are farmed for human consumption tripled. To determine whether heat produced by these warm-blooded animals and birds was responsible for the temperature rise, publicly available databases were scrutinized for human population growth and livestock production, as well as global energy use, and heat emission values were calculated. Using the heat transfer equation, the total calculated temperature rise from biological heat production by warm-blooded animals over the surveyed time period was found to be sufficient to account for the observed temperature rise, not counting a small additional contribution from industrial waste heat. Subject to verification of the methods used in this analysis, recalculation of greenhouse gas emission targets may be required, with consideration given to measures aimed at both reducing population growth and production of animals for human consumption.
Comparison of item response theory ability and item parameters according to classical and Bayesian estimation methods
Authors: Selçuk Eray , Demir Ergül
Published: May 2024

This research aims to compare the ability and item parameter estimations of Item Response Theory according to Maximum likelihood and Bayesian approaches in different Monte Carlo simulation conditions. For this purpose, depending on the changes in the priori distribution type, sample size, test length, and logistics model, the ability and item parameters estimated according to the maximum likelihood and Bayesian method and the differences in the RMSE of these parameters were examined. The priori distribution (normal, left-skewed, right-skewed, leptokurtic, and platykurtic), test length (10, 20, 40), sample size (100, 500, 1000), logistics model (2PL, 3PL). The simulation conditions were performed with 100 replications. Mixed model ANOVA was performed to determine RMSE differentiations. The prior distribution type, test length, and estimation method in the differentiation of ability parameter and RMSE were estimated in 2PL models; the priori distribution type and test length were significant in the differences in the ability parameter and RMSE estimated in the 3PL model. While prior distribution type, sample size, and estimation method created a significant difference in the RMSE of the item discrimination parameter estimated in the 2PL model, none of the conditions created a significant difference in the RMSE of the item difficulty parameter. The priori distribution type, sample size, and estimation method in the item discrimination RMSE were estimated in the 3PL model; the a priori distribution and estimation method created significant differentiation in the RMSE of the lower asymptote parameter. However, none of the conditions significantly changed the RMSE of item difficulty parameters.
Can Stem Cell Therapy be an Effective Therapeutic Option for Complex and Neurological Conditions?
Authors: Lo Sophea , Gantioque Raymund
Published: May 2024

This article explores the feasibility and potential benefits of stem cell therapy as a promising therapeutic intervention for individuals facing severe behavioral and cognitive impairments, targeting underlying neurological mechanisms to offer potential symptom improvement and function restoration, thereby enhancing the quality of life for patients and potentially alleviating stress and burnout among caregivers. The aims of the study include investigating the efficacy of stem cell therapy in addressing these impairments and evaluating its potential to alleviate caregiver burden. Through a comprehensive review of existing literature, clinical trials, and studies, this research synthesizes the mechanisms of stem cell therapy, potential applications, clinical trial outcomes, caregiver experiences, and economic implications. The methods employed involve analyzing diverse data sources to provide a holistic understanding of the possibilities and challenges associated with stem cell therapy. Key outcomes of the study include highlighting promising results from clinical trials targeting conditions such as autism spectrum disorder, Parkinson's disease, and Crohn's disease, which underscore the transformative potential of stem cell therapy in patient care. Additionally, economic implications suggest potential reductions in healthcare costs and alleviation of financial strain on individuals, families, and healthcare providers. Stem cell therapy represents a paradigm shift in healthcare, promising to redefine treatment approaches and alleviate broader societal burdens associated with complex neurological conditions. The relevance of the study lies in emphasizing the need for continued research, ethical considerations, and multidisciplinary collaboration to ensure the safe and effective integration of stem cell therapy into clinical practice, ultimately offering new hope and improved care for patients, caregivers, and healthcare systems worldwide.
ACTIVIDADES DIDÁCTICAS PARA EL DESARROLLO DE HABILIDADES EN LA ESCRITURA EN NIÑOS DE PRIMERO AÑO DE BÁSICA
Authors: Mora García Olga Elizabeth , Lescay Blanco Dayana Margarita
Published: May 2024

El proceso de enseñanza y aprendizaje de la escritura en los niños es fundamental para su desarrollo académico y cognitivo, sin embargo, esta etapa puede presentar desafíos particulares debido a la necesidad de adquirir habilidades básicas de escritura. En este contexto, los niños de primer año de educación básica de la Unidad Educativa Cristo Rey de la ciudad de Portoviejo, a menudo enfrentan problemas en el desarrollo de habilidades de escritura, como dificultades en la motricidad fina y la falta de conciencia fonológica. Por esta razón, el objetivo de este estudio es diseñar actividades didácticas que favorezcan el desarrollo de habilidades en la escritura de los niños. La metodología empleada consistió en un enfoque mixto, así mismo se utilizó la técnica de la entrevista y una guía de observación, las cuales fueron aplicadas a 3 docentes y 18 niños.
EL MARKETING VERDE COMO INSTRUMENTO EN LA GESTIÓN ESTRATÉGICA DE LAS EMPRESAS
Authors: Calle García Aldrin Jefferson , Garcia Loor Escarleth Briggy , Lucas Anchundia Emily Daniela , Holguin Magallanes Ashton Justin
Published: May 2024

Este estudio se centra en el marketing verde como instrumento en la gestión estratégica de las empresas, para ello se investigó la efectividad de las estrategias de marketing verde en la mejora del desempeño empresarial y la consecución de objetivos sostenibles. Mediante una metodología que incluyó análisis comparativos, estudios de casos e información sobre sostenibilidad, se examinaron los beneficios tangibles del marketing verde y su impacto en la diferenciación de marca y la lealtad del cliente. Se destacaron empresas líderes, como Patagonia y Tesla la cual aumentó las ventas de vehículos eléctricos en un 35% el 2022, lo que demuestra el impacto positivo del marketing verde en el crecimiento de la empresa, de igual manera otras empresas que han implementado con éxito estrategias de marketing verde han logrado resultados significativos en términos de reducción de huella ambiental, mejora de la reputación de la marca y aumento de la rentabilidad, se discutieron diversas estrategias y metodologías, incluyendo el uso del marketing verde en diferentes sectores empresariales y la integración de prácticas de biofilia.
USO ESTRATÉGICO DE LA INTELIGENCIA ARTIFICIAL EN LA GESTIÓN DE LA CADENA DE SUMINISTRO EMPRESARIAL
Authors: Calle García Jonás Sneider , Pincay Delgado Maria Antonella , Mendoza Pionce Bryan Saúl , Bravo Quijije Genesis Stefany
Published: May 2024

Este estudio analizó el uso estratégico de la inteligencia artificial (IA) en la gestión de la cadena de suministro empresarial con el objetivo de optimizar la eficiencia, la precisión y la toma de decisiones. Se llevó a cabo una revisión exhaustiva de la literatura académica y casos empresariales relevantes para analizar el impacto de la IA en la optimización de procesos logísticos, la toma de decisiones y la eficiencia operativa en la cadena de suministro. Se aplicaron métodos analíticos, inductivos y deductivos para desglosar y examinar críticamente la información recopilada. Los resultados revelaron que la implementación de la IA conlleva beneficios significativos. Por ejemplo, Walmart ha logrado reducir los niveles de inventario en un 20% y mejorar la precisión de las previsiones de ventas en un 15% mediante el uso de sistemas de predicción de demanda basados en IA. Empresas como Procter & Gamble han experimentado una reducción del 30% en los niveles de inventario y una mejora del 20% en la precisión de las previsiones de ventas gracias a algoritmos de IA.
The Intra- and Intermolecular Friedel-Crafts Acylation of Amino Acid Derivatives in
Stereo-retarded Manner
Authors: Tachrim Zetryana Puteri , Hashimoto Makoto
Published: May 2024

:

The Friedel-Crafts acylation of natural or unnatural amino acids in stereoretarded
manner is willing to prescribed here. Depending on its main skeleton, the typical
intra- and intermolecular Friedel-Crafts reaction of amino acids can be differentiated. The
unique amino acid’s general structure can contribute to the reaction between its carboxyl
group and the side chain. Depending on the Friedel-Crafts reaction condition, the amino
acid’s optical retention can be retarded. This perspective can contribute to the development
of this one-century reaction in the field of organic chemistry.
The Progress and Future of Artificial Intelligence in Nursing Care: A Review
Authors: Mahmoudi Hassan , Moradi Mohammad Hesam
Published: May 2024

Introduction

The utilization of novel technologies in contemporary times not only reduces the cost associated with healthcare but also improves the efficiency of hospital resources and elevates the standard of medical assistance. One of the new technologies used in the field of health is Artificial Intelligence (AI). The purpose of this study is to investigate the application of AI in the field of nursing.

Materials and Methods

The present investigation was conducted in the year 2023 utilizing a review methodology and an innovative scientific inquiry. Comprehensive research was performed in reliable databases such as PubMed, Scopus, Google Scholar, Science Direct, and Springer, using the keywords AI, smart hospital, nursing, and health care to accomplish the intended objectives. From 2016 to 2023,120 articles were chosen as the initial selection. Studies that were not related to the subject matter were excluded from the analysis afterward.

Results

After searching and eliminating duplicate articles through objective screening, a total of 98 articles were reviewed, with 63 ultimately selected for the study. Within the realm of nursing care, research has been conducted in various areas, such as electronic health records (13 studies), health information collection and analysis (27 studies), healthcare cost analysis (16 studies), and the implementation of smart technology and hospitals (7 studies). The integration of AI technology has shown promise in enhancing nursing care by reducing diagnostic errors, improving emergency response times, improving patient care quality and psychological support, and enabling remote care for elderly patients through the use of smart technology.

Conclusion

AI is a significant technological advancement that can directly impact the operational effectiveness of healthcare organizations. This is achieved through the optimization of healthcare business processes and the enhancement of patient safety. However, limited research has been conducted regarding the affordability and economic aspects of AI implementation. Therefore, it is advisable for healthcare policymakers to establish the necessary infrastructure to leverage this technology, which will facilitate a more effective therapeutic and economic approach.
Reconstructing the Holocene Development of Lake Chaika as an Example of Wetland Formation within the Sand Spit Environment Dynamics: A Case Study from the Curonian Spit, Southeastern Baltic, Russia
Authors: Napreenko-Dorokhova Tatiana , Ludikova Anna , Napreenko Maxim , Sosnina Irina
Published: May 2024

The paper provides original data that shed light on the formation dynamics of Lake Chaika, which is situated in the central part of the Curonian Spit and is the only large water body in the sand spits of the southeastern Baltic. Based on the multi-proxy approach, incl. investigation of the lithological structure of the bottom sediment cores, loss-on-ignition analysis, diatom analysis, study of macrofossil remains, and radiocarbon dating, we revealed that Lake Chaika was formed already in historical time, around 200 years ago. Before this period, the lake kettle, presumably, has not submerged during the Littorina transgressions, enabling the terrestrial development of the ecosystems on the moraine protrusion. During the mid-late Holocene (6700–150 cal BP), this depression was occupied by the peat-forming fen and alder carr communities. The peat deposits are separated from the overlying layers of gyttja by the thin sand horizon. We consider it a time marker for the so-called “sand disaster”, which occurred on the territory of the Curonian Spit in the 18th century (≈1700–1800). The change in the hydrological regime of the lake launched the ecosystem shifts during the last two centuries: from the water body to a wetland and vice versa. It is stated eight formation phases of the lake’s ecosystem: the terrestrial development without wet habitats (8900–6700 cal BP), the period of alder carrs (6700–3400 calBP), the sedge fen period (3400–450 cal BP), the period of inundated forest (1500–1700 AD), the “sand disaster” period (1700–1800 AD), the period of eutrophic water body (1800–1900 AD), the period of terrestrialised wetland (1900–1950 AD), and the period of secondary development of eutrophic water body (after 1950 AD).
Intramedullary stabilization of dislocated clavicle fractures with a compression rod
Authors: Hercen H.I. , Hapon O.M. , Bilonozhkin H.H.
Published: May 2024

Despite the favorable prognosis of conservative treatment for clavicle fractures, unsatisfactory consequences reach 10–30 % cases. Surgical methods of treatment for dislocated clavicle fractures, such as osteosynthesis with a plate or an elastic titanium rod, are mostly used in practice. The disadvantage of the latter is the possible migration of the implant with perforation of the skin. The purpose was to study the effectiveness of an intramedullary rod, improved by us, for osteosynthesis of dislocated clavicle fractures type OTA 15A and OTA 15B according to the AO/ASIF classification. The essence of the improvement was the possibility of closed minimally invasive intramedullary osteosynthesis of the clavicle body, with a simplified technique of the surgical intervention itself, prevention of implant migration. The latter was achieved by the fact that one of the ends of the rod had a drill, which eliminated the need for predrilling the medullary cavity of the clavicle to insert the rod, and its opposite end had a thread onto which a nut is screwed to achieve compression between the clavicular fragments. Forty-two patients with closed dislocated clavicle fractures were under supervision in the clinic of traumatology and orthopedics of Kyiv City Clinical Hospital 6. They underwent intramedullary osteosynthesis for clavicle fractures with an improved compressing rod (closed in 28 cases, open in 14) under regional anesthesia. In dyna-mics of the postoperative period, a clinical and radiological examination was performed, the severity of the pain syndrome and the function of the upper limb were assessed according to the visual analog scale (VAS), Disability of Arm, Shoulder and Hand (DASH). As shown by the results of X-ray examinations, the average period of clavicle fracture union was 10.1 ± 1.4 weeks (range 8–12 weeks). During the observation of the patients, favorable dynamics on the VAS and DASH were noted; by the end of the study (12 months after the operation), the functional capabilities of the upper limb on the DASH corresponded to 1.54 ± 0.84 points, VAS score was 9.60 ± 2.11 points. The improved construction of the intramedullary rod for osteosynthesis of dislocated clavicle fractures of the OTA 15A and OTA 15B type can be recommended for use in practice, as it has demonstrated favorable clinical, radiological, and functional outcomes.