bluuebunny/crossref_metadata_2025 huggingface dataset:
Do Inflammatory Cytokines Mediate the Therapeutic Benefits of Exercise in Depressive Disorders? A Scoping Review of Recent English Literature
Authors: Asgari Kimia , Abdullatif Fatema , Ali Amina
Published: May 2021

Introduction: Studies have investigated the pathogenesis of depression, with few focusing on the elevation of pro-inflammatory cytokine levels in depression. This article undertakes a scoping review of the available research to explore the current understanding of the role of pro-inflammatory cytokines in depression. Furthermore, the ability of exercise to reduce depression severity through lowering these cytokine levels is examined.
Method: Analysis of online research articles was used to investigate the intended objective, and 18 English-based papers published between 2010-2020 were selected. These studies examined pro-inflammatory cytokine levels in healthy, depressed, diseased and/or physically active patients or research animals as a primary or secondary outcome. Other inclusion criteria such as number of participants and appropriate control selection were used to further refine the search results.
Results: Based on the conducted search, sufficient evidence seems to exist to support an association between elevated levels of pro-inflammatory cytokines, IL-6, TNF-α, IL-1β and incidence of depression. Exercise increases the production and release of anti-inflammatory cytokines and reduces baseline levels of pro-inflammatory cytokines. These anti-inflammatory properties of physical activity supported by exercise-focused studies, can explain the mechanism behind reduced depressive symptoms after a period of regular exercise.
Discussion: The available data supports an association between elevated pro-inflammatory cytokine levels and depression, and the antidepressant effects of exercise. However, there is no evidence of causality between elevated levels of pro-inflammatory cytokines and depression. Whether pro-inflammatory cytokine levels changed as a result of regular exercise, the specific types of pro-inflammatory cytokines that experienced the change, and the extent to which they did, depended on the participant, and the exercise activity.
Conclusion: Measuring the levels of pro-inflammatory cytokines can potentially provide an objective method for diagnosing depression. Due to the potential anti-inflammatory effects of exercise, programs can be designed as a non-pharmacological treatment in mild cases and augment the effectiveness of drug therapy in severe cases.
First record of Phlegmariurus pruinosus (Herter) B. Øllg. (Lycopodiaceae) for Ecuador from the Cordillera del Cóndor range
Authors: Perez Alvaro , Zapata Nicolás , Cevallos Daniela , Persson Claes , Rea Edison , Olgaard Benjamin
Published: May 2021

Durante una reciente expedición botánica a la Reserva Biológica El Quimi, provincia de Morona Santiago, región de la Cordillera del Cóndor, Phlegmariurus pruinosus (Herter) B. Øllg. fue registrado por primera vez para el Ecuador. Se presenta una descripción morfológica, fotografías y un mapa de distribución actualizado. Adicionalmente, se discute su relación con otras especies morfológicamente similares. Un total de 67 especies de Phlegmariurus están registrados para el Ecuador.
Vom Eingebildeten Kranken und dem Zauberberg
Authors: Karb Johanna Lea
Published: May 2021

Hypochondrie ist, obgleich es sich dabei keineswegs um ein neues Störungsbild handelt, auch heutzutage noch eher wenig beforscht (vgl. Nissen, 2015). Eine Differenzialdiagnose ist Küchenhoff (1985) zufolge i.d.R. schwierig, da hypochondrische Symptome oft im Kontext anderer Störungsgruppen auftreten und sich mit diesen überschneiden (Hirsch, 2011, S. 77). Nach Röder et al. (1995) können diese entweder als »Internalisierung eines ambivalent besetzen Objekts, bzw. Selbstobjekts« oder als »aggressive Affekte und Konflikte« verstanden werden (S. 1091ff.). Die Beziehung zur Mutter spiele dabei eine wichtige Rolle – Patient*innen berichten häufig, dass sich diese zwar punktuell einfühlen konnte, sich mitunter jedoch unvorhersehbar aus dem Kontakt zurückgezogen habe und/oder eine reale, traumatisierende Trennung vorlag (Nissen, 2010, S. 3). Ein charakteristischer Konflikt ist laut Hirsch (2011) außerdem, dass eigene Selbstständigkeitswünsche und Autonomiebestrebungen mit dem Angewiesensein auf die primäre Bezugsperson sowie die damit ebenfalls einhergehende Angst vor Objektverlust verschmelzen, wenn die Trennungswünsche des Kindes mit der Fantasie, selbst verlassen und damit bestraft zu werden, einhergehen. Dieser Artikel widmet sich der Psychodynamik der Hypochondrie, welche anhand zweier »Fälle« aus der klassischen Literatur – Argan, dem Protagonisten aus Molières Der eingebildete Kranke, sowie Hans Castorp aus Der Zauberberg von Thomas Mann – näher beleuchtet und exemplifiziert wird. Anschließend wird auf einige Besonderheiten in der psychodynamischen Intervention eingegangen.
Das Unheimliche und die Bruchlinien im Selbst – leidvoll, kreativ, weiblich, menschlich?
Authors: Küchenhoff Joachim
Published: May 2021

Das Unheimliche verunsichert und verfremdet das als selbstverständlich vorausgesetzte Alltagsbewusstsein. Sigmund Freud hat in seiner wegleitenden Arbeit zum Sandmann E.T.A. Hoffmanns hervorgehoben, dass das Gefühl des Unheimlichen aus der Begegnung mit den verdrängten, im Grunde gut vertrauten infantilen Komplexen resultiert. Die vorliegende Arbeit will das Spektrum der Interpretationsmöglichkeiten des Unheimlichen erweitern. Zunächst wird das Phänomen des Unheimlichen beschrieben und definiert. Nach einer ausführlichen Würdigung der Gedanken Freuds zur triebpsychologischen Deutung des Phänomens wird das Unheimliche als Infragestellung der Integration des Selbst in einen neuen Zusammenhang gestellt und neu verstanden; die mit dem Unheimlichen verbundenen Bruchlinien der (Selbst-)Erfahrung werden nacheinander bezogen auf den Identitätszweifel, auf traumatische Erfahrungen, die Angst vor dem Zerfall des Körperbilds, die Demarkation des Selbst und ihre Bedrohung durch »Abjekte«. Gerade weil (und nicht obwohl) das Unheimliche verunsichert und erschüttert, hat es eine kreative Kehrseite, denn Kreativität ist an die temporäre Desintegration von Erfahrungen gebunden. Der Beitrag endet mit einer Kritik an Weiblichkeitskonzepten in der Psychoanalyse, die das Feminine und das Unheimliche zu eng verbinden. Stattdessen wird es als Teil der conditio humana verstanden.
Überlegungen zur Beziehungsdynamik in der Therapie Älterer
Authors: Peters Meinolf
Published: May 2021

Nach der Schilderung von Therapeuten findet die Therapie Älterer oftmals in einer »familiäreren Atmosphäre« statt, was mit besonderen Herausforderungen für Therapeuten verbunden ist. Im Beitrag wird diese Beziehungsdynamik als Nähe-Distanz-Problematik konzeptualisiert. Es werden theoretische Überlegungen zum Verständnis dieser Dynamik vorgestellt, ihre klinischen Facetten und Wirkungen beschrieben sowie Möglichkeiten des Umgangs damit.
Depression in a household population sample in Aracaju (Sergipe, Brazil)
Authors: Menezes Mariana Siqueira , Faro André
Published: May 2021

This study aimed to detect the prevalence of symptoms of depression in a representative household population sample from Aracaju (Sergipe, Brazil), as well as estimating the chances of positive diagnostic screening of depression, based on socio-demographic and general health profiles. The sample was composed of 690 participants. The Beck Depression Inventory (BDI) and questionnaires about socio-demographic and health-related data were used. Almost 35% of participants had positive screening diagnosis of depression. The Logistic Regression showed that those people who perceived themselves as sick, non-religious, lacked a college degree, smokers or who were obese, smokers composed the profile of individuals with a greater chance to be in the BDI positive group. These findings are important due to the lack of similar studies in Brazilian Northeast region.
PELATIHAN PEMBUATAN NATA DE COCO DARI LIMBAH AIR KELAPA DI DESA DUNU KECAMATAN MONANO KABUPATEN GORONTALO UTARA
Authors: Mardin Herinda , Lasalewo Trifandi
Published: May 2021

ABSTRAK

 

Tanaman kelapa memiliki beragam manfaat mulai dari buah, batang, daun dan air kelapa. Buah kelapa dimanfaatkan oleh masyarakat di desa Dunu kecamatan Monano Kabupaten Gorontalo Utara menjadi kopra. Dalam proses pembuatan kopra, air kelapa di desa Dunu kurang dimanfaatkan secara maksimal sehingga menjadi limbah. Limbah air kelapa dapat digunakan dalam pembuatan nata de coco dengan menggunakan mikroorganisme Acetobacter xylinum. Untuk itu, dengan melimpahnya air kelapa di desa Dunu, sehingga dilakukan pelatihan pembuatan nata de coco. Tujuan dari kegiatan pelatihan ini diharapkan dapat memberikan informasi, skill dan pengetahuan kepada masyarakat desa Dunu dalam memanfaatkan limbah air kelapa menjadi produk nata de coco sehingga mampu meningkatkan pendapatan ekonomi masyarakat juga mampu menjaga kebersihan lingkungan sekitar dari limbah air kelapa. Pelatihan pembuatan nata de coco dari limbah air kelapa di desa Dunu, Kecamatan Monano Kabupaten Gorontalo Utara ini dilaksanakan pada hari Minggu tanggal 20 September 2020 dengan melibatkan 65 orang peserta bertempat di aula kantor desa Dunu. Metode pelaksanaan kegiatan ini adalah pelatihan langsung dan praktik. Hasil dari kegiatan pelatihan pembuatan nata de coco dari limbah air kelapa ini adalah peserta mendapatkan informasi, skill dan pengetahuan mengenai cara pembuatan nata de coco dari air kelapa. Selain itu, peserta juga mendapat pengetahuan dan skill mengenai cara pembibitan starter nata de coco dari mikroorganisme bakteri Acetobacter xylinum.
Mendialogkan Hakikat Hukum dan Keadilan Pada Berbagai Aliran Pemikiran Hukum dalam Novel Les Miserables
Authors: Kasim Helmi
Published: May 2021

Justice should be clearly presented in the wording of written law since it will serve as a basis by law enforcement officer and judges in adjudicating cases. The spirit of justice that is contined in the written law should also inspire the way law is enforced and decision made. This paper tries to reflect the essence of justice and law through various plots and characters in Victor Hugo’s novel Les Miserable by looking at it from the perspective of various schools of legal thought. The reflection made shows that a legal event can be studied using various perspectives based on schools of thought in legal science. In the analysis, natural law schools of thought, positivism and feminist jurisprudence were used. Dialoguing these various schools of thought leads to a perspective on how law and justice should be perceived and then expressed normatively before being applied to society.
An Overview of Mixed and Multi Method Research
Authors: Kasirye Faiswal
Published: May 2021

This paper reviews the two prominent research approaches (mixed and multimethod). it gives the pros and cons of each and distinguishes what each one means and why it should be chosen and used in research studies.
Anotasi Artikel Jurnal Pembinaan Etika Peserta Didik Melalui Pembelajaran Tematik-Integratif Di Sekolah Dasar
Authors: Fitri Desy Dahrina
Published: May 2021

Pada praktik pembelajaran tematik-integratif kurikulum 2013 di jenjang Sekolah Dasar, peserta didik dituntut untuk paham atas materi, aktif dalam partisipasi pembelajaran. Pembelajaran tematik-integratif dengan memasukan pendidikan etika dimaksudkan agar peserta didik mampu memiliki; budi pekerti, sopan santun serta karakter. Praktiknya dapat diintegrasikan ke semua mata pelajaran yang disampaikan guru dengan suatu tema tertentu. Pembelajaran tematik-integratif dipahami sebagai satu pendekatan dalam pembelajaran dimana memberikan ruang integrasi terhadap kompetensi dari beberapa mata pelajaran. Kompetensi yang demikian kemudian disatukan dalam bentuk tema diharapkan memberikan bermakna kepada peserta didik. Demikian, peserta didik memperoleh pengalaman belajar yang bermakna dan pengetahuannya tidak dibatasi dalam disiplin ilmu tertentu. Pembelajaran diyakini mampu mengembangkan ranah kognitif, afektif, dan juga psikomotor peserta didik dengan seimbang dan menyeluruh.
Over-expression of desumoylating isopeptidase 1 in human endometrial cancer.
Authors: Mamoor Shahan
Published: May 2021

Gynecologic cancers including cancers of the endometrium are a clinical problem (1-4). We mined published microarray data (5, 6) to discover genes associated with endometrial cancers by comparing transcriptomes of the normal endometrium and endometrial tumors from humans. We identified desumoylating isopeptidase 1, encoded by DESI1, as among the most differentially expressed genes, transcriptome-wide, in cancers of the endometrium. DESI1 was expressed at significantly higher levels in endometrial tumor tissues as compared to the endometrium. Importantly, in human endometrial cancer, primary tumor expression of DESI1 was correlated with recurrence-free survival in black patients with high mutational burden. DESI1 may be a molecule of interest in understanding the etiology or progression of human endometrial cancer.
Spherical accretion of a perfect fluid onto a black hole
Authors: Guzmán Murillo Francisco S , Alvarez Ríos Iván , Romero Amezcua Alejandro , González José A
Published: May 2021

In this academic paper we present in detail the numerical solution of the accretion of a perfect fluid onto a black hole. The conditions are very simple, we consider a radial flux being accreted by a Schwarzschild black hole. We present two scenarios: 1) the test field case in which the fluid does not affect the geometry of the black hole space-time background, and 2) the full non-linear scenario, in which the geometry of the space-time evolves simultaneously with the fluid according to Einstein's equations.In the two scenarios we describe the black hole space-time in horizon penetrating coordinates, so that it is possible to visualize that accretion actually takes place within the numerical domain.For the evolution of matter we use the Valencia formulation of relativistic fluid dynamics. In the non-linear scenario we solve the equations of geometry using the ADM formulation of General Relativity, with very simple and intuitive gauge and boundary conditions, and include diagnostics related to the Apparent Horizon and Event Horizon growth.In view of the recent spectacular discoveries by the Event Horizon Telescope collaboration and further discoveries to come, the aim of this paper is to provide the necessary tools for interested graduate students in Black Hole Astrophysics, to enter into the accretion modeling starting from a considerable advanced starting point.
Supervision of Research at Higher Education: Perception and Practices of Supervisors in Karachi Pakistan
Authors: Mahesar Pervaiz Ali , Jabeen Farzana , Pathan Mubina
Published: May 2021

The purpose of this research study was to find the perceptions and practices of researchers who supervised the research scholars at the higher education level. It is the common complaint of the students that their supervisors do not cooperate and resultantly the research study does not complete quite well in time. A quality research approach was adopted for the purpose, and sixteen research supervisors were interviewed. Responses of the supervisors who were included in this research for finding problems the supervisors are facing in the process of research supervision at higher education level, data were collected through open-ended questions which were presented during personal interviews to supervisors from private and government universities, both from social sciences and from applied sciences. While the findings of this research show more than these problems which supervisors are facing. It is recommended that the supervisor's point of view should also take into consideration, and further researches should be conducted to analyses hidden areas of this process.
American Indian Identity in The Heirs of Columbus
Authors: Khan Mehwish Ali , Manzoor Fahmida , Mazhar Shumaila
Published: May 2021

The present study aims to explore the identity construction in The Heirs of Columbus. The Heirs of Columbus exhibits the chronic representations of primitive inferior Indian constructed by the Euro Americans through the exercise of colonialism. These representations have been spread on both conscious and unconscious levels to maintain power and colonial hegemony. Gerald Vizenor deconstructs the stereotype Indian through his writings hence refute the eurocentric notion of stereotype native. He unveils the Eurocentric ideology by rewriting history in a subversive ironical way, records the construction of Indian thus reconstructs him in his narration.
Opportunities and Challenges of Values Education for Vietnamese Students from the Experience of Other Nations
Authors: Hanh Vuong Thi Phuong
Published: May 2021

Value education has been featured and improved in educational programs in many countries over the last few decades and is becoming global. Therefore, this paper investigates values education in public schools, and experience from other nations and lessons learned for Vietnam. Many studies have been conducted on the prosocial and the development of values education. Especially, the studies about values education having become more and more common and focused. Hence, a review of the literature published from 2000 to 2020 on values education is carried out. A summary of findings and formulate for research on oriented values education is presented in the discussion section. This study will help to recognise the existing research issues and gaps and recommends areas for further investigation.
Histological changes in methotrexate hepatotoxicity after boron application and evaluation of serum thiol-disulfide balance
Authors: KİPALEV NEŞELİOĞLU Andaç , AKCAN Gülben , NAKKAŞ Hilal , NEŞELİOĞLU Salim , EREL Özcan , EVİRGEN Oya , ÖZGÜNER Meltem
Published: May 2021

Aim: Methotrexate, a folic acid antagonist, is a chemotherapeutic drug used in the treatment of various inflammatory diseases as well as some cancer types.The purpose of this study; It is the study of the effects of boric acid against the hepatotoxic side effects of methotrexate.

Materials and Methods: Male wistar albino rats were divided into five groups of six animals each. The rats in group 1 were used as a control group. Methotrexate was administered to the rats in group 2 and boric acid to the rats in group 3. While the rats in group 4 were given first methotrexate and then boric acid, the rats in group 5 were administered boric acid first and then methotrexate.

Results: Light microscopic examination revealed sinusoidal dilatation, hepatocyte degeneration, vascular congestion-thrombosis, and inflammatory infiltration in the livers of rats treated with methotrexate. It was observed that the protective effect of boric acid was more effective than its treatment. In the groups given methotrexate, the level of oxidative stress-related parameters such as lipid hydroperoxide, MPO and disulfide increased (p< 0.05), whereas the level of antioxidant parameters such as native thiol, total thiol and catalase decreased (p< 0.05).

Conclusion: In this study, it was determined that the protective effect of boric acid was more than the therapeutic effect in liver damage caused by methotrexate. Oxidative hepatotoxicity resulting from methotrexate application disrupted the thiol disulfide balance and caused it to shift in favor of oxidation.
Relationship between mean platelet volume and intensive care unit requirement in COVID-19 patients
Authors: AK Rohat , DOĞANAY Fatih
Published: May 2021

Objective: Our aim in this study is to examine the relationship between the mean platelet volume (MPV) and the intensive care unit (ICU) requirement in patients with 2019 coronavirus disease (COVID-19).

Methods: This retrospective observational study was conducted with patients who were diagnosed with COVID-19 in the emergency department of a tertiary hospital. The study was continued with the remaining 711 patients after using the inclusion and exclusion criteria. CHAID analysis was used as the decision tree method in analyzing the data. The relationship between ICU requirement and MPV were evaluated.

Results: There were 711 patients included in this study. The median age of the population was 64 (49-76). According to the CHAID analysis, the study population was divided into 2 classes as those who aged 58 years or younger (Younger Group) and those who older than 58 years (Older Group), and the relationship between the 8.3 threshold value of MPV and the ICU requirement was analyzed. For the Younger group, a significant difference was found in terms of ICU requirement based on the 8.3 threshold value of MPV.

Conclusion: Advanced age, high MPV and PLT values in COVID-19 patients, are associated with the ICU requirement. The 8.3 threshold value of MPV can be used as one of the parameters determining the ICU requirement in relatively young patients. In the geriatric age group, it is not beneficial to use MPV measurement to assign the ICU requirement. Multi-center studies with a large number of patients are needed to present the strength of the results of our study more clearly.
An unexpected complication in a hemodialysis patient: midodrine related A-V fistula dysfunction
Authors: DEMİR Mehmet Emin , ALP Çağlar
Published: May 2021

Arteriovenous fistula (AVF) dysfunction is one of the common obstacles in performing hemodialysis treatment. Acute and chronic thrombosis of the fistula, stenosis, and hematomas are the major causes of the dysfunction. Here, we present an unexpected complication of midodrine use which caused in AVF dysfunction in a female patient who was suffering from hemodialysis-related hypotension.
The role of YouTube® videos in heart surgery decision
Authors: ARSLAN Akın
Published: May 2021

Background: Finding a surgeon and center they can trust is essential for a patient who will be for heart surgery. YouTube® is a modern method at this decision stage as a visual source of information that includes many user comments. In this study, we examined how accurately YouTube® resources guide patients.

Method: The social media platform's official page (https://www.youtube.com) was used for this research. Keywords "heart surgery," "open-heart surgery," "robotic heart surgery" were selected as keywords for related video searches. Advertising promotions and videos with game content have been removed from search results. As the videos' evaluation criteria included in the study, relevance, date added, the number of views, views/likes rate, the descriptive response rate to comments, and video quality were determined.

Result: The most popular 1069 videos were evaluated between 05.10.2020 - 05.01.2021. Of these, 70 videos with the highest level of interest were evaluated. Video views median value is 26401 (IQR; 4968-1998337). Engagement rate median value 0,55 (IQR 0,40 -0,88). Average value median 1,67 (IQR 0,35 – 10,68). The comment/subscriber rate median value was 0.0010% (IQR; 0.0233% - 0.0585%).

Conclusion: Despite the ease of access to information sources in the information age, the importance of face-to-face meetings is still indispensable in information transfer. Because when it comes to illness, people look for knowledge, trust, and complacency. Patients want to know the person they will entrust their health to and ask questions repeatedly, even if it is the same question. Video sources can still only give a preliminary idea.
Metadata of Registries: Results from an Initiative in Health Services Research
Authors: Stausberg Jürgen , Harkener Sonja
Published: May 2021

Metadata management is an essential condition to follow the FAIR principles. Therefore, metadata management was one asset of an accompanying project within a funding scheme for registries in health services research. The metadata of the funded projects were acquired, combined in a database compatible with the metamodel of ISO/IEC 11179 “Information technology – Metadata registries” third edition (ISO/IEC 11179-3), and analyzed in order to support the development and the operation of the registries. In the second phase of the funding scheme, six registries delivered a complete update of their metadata. The mean number of data elements increased from 245.7 to 473.5 and the mean number of values from 569.5 to 1,306.0. The conceptual core of the database had to be extended by one third to cover the new elements. The reason for this increase remained unclear. Constraints from the grant might be causal, a deviation from an evidence-based development process as well. It is questionable, whether the revealed quality of the metadata is sufficient to fulfill the FAIR principles. The extension of the metamodel of ISO/IEC 11179-3 is in agreement with the literature. However, further research is needed to find workable solutions for metadata management.
COVID-19 preVIEW: Semantic Search to Explore COVID-19 Research Preprints
Authors: Langnickel Lisa , Baum Roman , Darms Johannes , Madan Sumit , Fluck Juliane
Published: May 2021

During the current COVID-19 pandemic, the rapid availability of profound information is crucial in order to derive information about diagnosis, disease trajectory, treatment or to adapt the rules of conduct in public. The increased importance of preprints for COVID-19 research initiated the design of the preprint search engine preVIEW. Conceptually, it is a lightweight semantic search engine focusing on easy inclusion of specialized COVID-19 textual collections and provides a user friendly web interface for semantic information retrieval. In order to support semantic search functionality, we integrated a text mining workflow for indexing with relevant terminologies. Currently, diseases, human genes and SARS-CoV-2 proteins are annotated, and more will be added in future. The system integrates collections from several different preprint servers that are used in the biomedical domain to publish non-peer-reviewed work, thereby enabling one central access point for the users. In addition, our service offers facet searching, export functionality and an API access. COVID-19 preVIEW is publicly available at https://preview.zbmed.de.
Machine Learning Approach to Optimize Sedation Use in Endoscopic Procedures
Authors: Syed Shorabuddin , Syed Mahanazuddin , Prior Fred , Zozus Meredith , Syeda Hafsa Bareen , Greer Melody L. , Bhattacharyya Sudeepa , Garg Shashank
Published: May 2021

Endoscopy procedures are often performed with either moderate or deep sedation. While deep sedation is costly, procedures with moderate sedation are not always well tolerated resulting in patient discomfort, and are often aborted. Due to lack of clear guidelines, the decision to utilize moderate sedation or anesthesia for a procedure is made by the providers, leading to high variability in clinical practice. The objective of this study was to build a Machine Learning (ML) model that predicts if a colonoscopy can be successfully completed with moderate sedation based on patients’ demographics, comorbidities, and prescribed medications. XGBoost model was trained and tested on 10,025 colonoscopies (70% – 30%) performed at University of Arkansas for Medical Sciences (UAMS). XGBoost achieved average area under receiver operating characteristic curve (AUC) of 0.762, F1-score to predict procedures that need moderate sedation was 0.85, and precision and recall were 0.81 and 0.89 respectively. The proposed model can be employed as a decision support tool for physicians to bolster their confidence while choosing between moderate sedation and anesthesia for a colonoscopy procedure.
Consolidated EHR Workflow for Endoscopy Quality Reporting
Authors: Syed Shorabuddin , Tharian Benjamin , Syeda Hafsa Bareen , Zozus Meredith , Greer Melody L. , Bhattacharyya Sudeepa , Syed Mahanazuddin , Prior Fred
Published: May 2021

Although colonoscopy is the most frequently performed endoscopic procedure, the lack of standardized reporting is impeding clinical and translational research. Inadequacies in data extraction from the raw, unstructured text in electronic health records (EHR) pose an additional challenge to procedure quality metric reporting, as vital details related to the procedure are stored in disparate documents. Currently, there is no EHR workflow that links these documents to the specific colonoscopy procedure, making the process of data extraction error prone. We hypothesize that extracting comprehensive colonoscopy quality metrics from consolidated procedure documents using computational linguistic techniques, and integrating it with discrete EHR data can improve quality of screening and cancer detection rate. As a first step, we developed an algorithm that links colonoscopy, pathology and imaging documents by analyzing the chronology of various orders placed relative to the colonoscopy procedure. The algorithm was installed and validated at the University of Arkansas for Medical Sciences (UAMS). The proposed algorithm in conjunction with Natural Language Processing (NLP) techniques can overcome current limitations of manual data abstraction.
i2b2 to Optimize Patients Enrollment
Authors: Bucalo Mauro , Gabetta Matteo , Chiudinelli Lorenzo , Larizza Cristiana , Bellasi Antonio , Zambelli Alberto , Barbarini Nicola
Published: May 2021

i2b2 data-warehouse could be a useful tool to support the enrollment phase of clinical studies. The aim of this work is to evaluate its performance on two clinical trials. We developed also an i2b2 extension to help in suggesting eligible patients for a study. The work showed good results in terms of ability to implement inclusion/exclusion criteria, but also in terms of identified patients actually enrolled and high number of patients suggested as potentially enrollable.
Impact of COVID-19 on Multiple Sclerosis Topic Discussion on Twitter
Authors: Giunti Guido , Claes Maëlick , Zubiete Enrique Dorronzoro , Rivera-Romero Octavio , Gabarron Elia
Published: May 2021

Introduction: Multiple sclerosis (MS) is one of the world’s most common neurologic disorders. Social media have been proposed as a way to maintain and even increase social interaction for people with MS. The objective of this work is to identify and compare the topics on Twitter during the first wave of COVID-19 pandemic. Methods: Data was collected using the Twitter API between 9/2/2019 and 13/5/2020. SentiStrength was used to analyze data with the day that the pandemic was declared used as a turning point. Frequency-inverse document frequency (tf-idf) was used for each unigram and calculated the gains in tf-idf value. A comparative analysis of the relevance of words and categories among the datasets was performed. Results: The original dataset contained over 610k tweets, our final dataset had 147,963 tweets. After the 10th of march some categories gained relevance in positive tweets (“Healthcare professional”, “Chronic conditions”, “Condition burden”), while in negative tweets “Emotional aspects” became more relevant and “COVID-19” emerged as a new topic. Conclusions: Our work provides insight on how COVID-19 has changed the online discourse of people with MS.
Reflection on Telemedicine Competencies in Spanish Medicine Degrees After the COVID-19 Pandemic
Authors: Garcia-Garcia Julian Alberto , Sanchez-Gómez Nicolas , Ramírez De Verger Cristina , Bautista-Llamas Maria Jose , Navarro-Pando Jose
Published: May 2021

The pandemic suffered in 2020 following the appearance of the SARS-CoV-2 virus has marked a radical change in the way in which the basic pillars of international, and more specifically Spanish, society are understood. The existing social and economic model has had to adapt abruptly and urgently to the reality of what has happened. The impact that these changes will have after the pandemic is still unclear, but it may be surmised that many of them are here to stay. The use of information and communication technologies has been critical in the pandemic scenario and also in the health environment, where factors like telemedicine have come to play a key role for society. This work presents an initial analysis of how degrees in Medicine train students for telematic work with patients and provides a series of reflections based on the pandemic which may serve as a point of departure for future studies.
Mobile Remote Presence Robots for Medical Consultation and Social Connectedness
Authors: Lueg Christopher , Jungo Valérie
Published: May 2021

We demonstrate that Mobile Remote Presence systems (MRP) aka telepresence robots can be successfully used in certain types of medical consultation such as consultation from a distance with residents of nursing homes. We argue that MRP afforded media richness also allows for supporting social connectedness during medically recommended isolation regimes similar to the ones that are implemented in residential care homes around the world during the SARS-CoVID-2 pandemic. Specifically, our research found that MRP are perceived as a more natural medium compared to typical telephones or videoconferencing via computers or tablets. MRP allow conversations to become more dynamic and engaging since remote participants are able to adjust their remote position and perspective during a conversation. Participants in our experiments reported they would be willing to engage even in difficult or emotional topics when using MRP however there are also certain types of situations that would still ask for face-to-face conversations.
Capacity Building for a Stronger Workforce in the Public Healthcare Sector
Authors: Netteland Grete , Hansen Cecilie Slokvik , Wasson Barbara
Published: May 2021

In a more and more demanding sector, healthcare leaders are in need of relevant and up-to-date competencies. The paper describes the iComPAss-project that aimed to increase the quality of a Master’s programme for healthcare leaders, making sure that the competencies students are taught and should develop during their studies are aligned with what is relevant for their current and future practices. A method for identifying needed competencies in the field of practice was developed and used. This led to an understanding of the need for increased collaboration between the Master’s programme, the field of practice, and working life.
Very Early Robot-Assisted Mobilization of Intensive Care Patients – A Scoping Review
Authors: Klamt Amrei C. , Schmidbauer Lena , Warmbein Angelika , Rathgeber Ivanka , Fischer Uli , Eberl Inge
Published: May 2021

This scoping review gives an overview of current research activities in the field of very early mobilization with robotic devices of intensive care patients. It presents the effect of very early, robot-assisted mobilization on intensive care patients based on their outcomes.
Ontological Models Supporting Covariates Selection in Observational Studies
Authors: Pressat Laffouilhère Thibaut , Grosjean Julien , Bénichou Jacques , Darmoni Stefan J. , Soualmia Lina F.
Published: May 2021

In the context of causal inference, biostatisticians use causal diagrams to select covariates in order to build multivariate models. These diagrams represent datasets variables and their relations but have some limitations (representing interactions, bidirectional causal relations). The MetBrAYN project aims at building an ontological-based process to tackle these issues. The knowledge acquired by the biostatistician during a methodological consultation for a research question will be represented in a general ontology. In order to aggregate various forms of knowledge the ontology will act as a wrapper. Ontology-based causal diagrams will be semi-automatically built. Founded on inference rules, the global system will help biostatisticians to curate it and to visualize recommended covariates for their research question.
ТЕОРЕТИЧНІ ЗАСАДИ УПРАВЛІННЯ РЕЗУЛЬТАТИВНІСТЮ МЕНЕДЖМЕНТУ ОРГАНІЗАЦІЇ
Authors: Пащенко Ольга , Куліш Наталія
Published: May 2021

У статті уточнено визначення поняття «результативність менеджменту». Запропоновано під результативністю діяльності підприємства розуміти узагальнюючу характеристику одержаних (свідомо й заздалегідь визначених цілей та встановлених завдань) різного роду позитивних ефектів, пов’язаних із продуктивним використанням економічних ресурсів на основі повної реалізації наявних можливостей та потенціалу розвитку певного підприємства. Досліджено критерії вимірювання результативності організації. Виявлено, що одним із пріоритетних критеріїв результативності є конкурентоспроможність. Визначено систему показників-індикаторів вимірювання результативності діяльності підприємства на основі виділення окремих груп показників, що дають змогу виміряти ефективний процес досягнення виробничих, фінансових, трудових та інших результатів функціонування підприємства.
ОНЛАЙН ТЕХНОЛОГІЇ ЯК ІНСТРУМЕНТ ДЛЯ РОБОТИ З АНГЛОМОВНОЮ ЛЕКСИКОЮ ПРОФЕСІЙНОГО СПРЯМУВАННЯ
Authors: Риб’як В. В. , Коваль А. В.
Published: May 2021

У статті обґрунтовується доцільність використання онлайн технологій для розвитку лексичної компетенції у межах викладання курсу англійської мови професійного спрямування. Незважаючи на той факт, що у науковій літературі формуванню лексичної компетенції присвячені десятки наукових праць, в умовах дистанційного навчання перед викладачами англійської мови професійного спрямування постають нові виклики, а саме: які засоби є ефективними для оволодіння словниковим запасом іноземної мови в умовах позаудиторних занять, та яким чином здійснювати контроль сформованості навичок використання англійської лексики у сфері професійного спілкування. У статті наводиться системний аналіз можливостей сучасних веб-додатків для роботи з англійською термінологією за фахом, розглядаються варіанти їх застосування для створення тренувальних вправ, а також для розробки гнучкої системи контролю та перевірки засвоєння лексичних одиниць за фахом майбутньої спеціалізації. У роботі узагальнюється досвід практичного застосування веб-додатків під час дистанційного навчання з майбутніми військовослужбовцями, наводиться система опрацювання одних і тих же лексичних одиниць на різному етапі їх засвоєння: від впізнавання та співвідношення із відповідником рідної мови до використання у певному контексті.

У статті обґрунтовано доводиться, що веб-додатки є ефективним засобом формування лексичної компетенції. Вони доступні та достатньо зручні у застосуванні. Крім явних переваг щодо опанування іноземною термінологією використання зазначених веб-додатків, сприяє розвитку навичок самостійної роботи у студентів, а також навичок самоорганізації та вміння керувати власним часом.
РОЗРОБКА МОДЕЛІ ІНТЕЛЕКТУАЛЬНОГО БЕЗПЕЧНОГО СЕРЕДОВИЩА ЗАСОБАМИ ТЕХНОЛОГІЇ ІНТЕРНЕТ РЕЧЕЙ (INTERNET OF THINGS)
Authors: Роганов М. Л. , Роганов М. М.
Published: May 2021

В статті розглядаються питання впровадження сучасної концепції Інтернет речей (Іnternet of things) на базі IoT-платформи для створення безпечного середовища, яке забезпечує безпеку, комфорт і ресурсозбереження для всіх користувачів. Безпека людей – це важливий фактор, до якого не можна підходити «формально». Він повинен визначати, як система реагує на присутність певних вразливих категорій людей: немовлят, дітей дошкільного віку, вагітних жінок, людей з обмеженими можливостями тощо. Для них існують специфічні обмеження, незалежно від приміщення і тих людей, що там знаходяться. Визначено, що недоліком технології управління «SMART будинком» за профілями є можливість ненавмисного нанесення шкоди певним категоріям людей. На прикладі «SMART будинку» показано, як за допомогою розробленої моделі інтелектуального динамічного синтезу профілів користувачів можна забезпечити компроміс між комфортом і безпекою. Сучасна система безпечного середовища повинна вміти приймати рішення в кожній конкретній ситуації і підлаштовуватися під певні категорії, знаходячи компроміс (з огляду на пріоритети профілів і обмеження).

Запропонована модель гнучкого управління параметрами устаткування в системі «SMART будинок» з підвищеним ступенем комфорту і безпеки за рахунок динамічного синтезу компромісного профілю користувача є варіативною і може бути впроваджена в будь якому приміщені, наприклад у дитячих садках, закладах освіти тощо.

Ця модель є відкритою системою і може корегуватися і вдосконалюватися відповідно до конкретних умов.
ТЕХНОЛОГІЯ ЛІДЕРСТВА В УМОВАХ ЗАКЛАДУ ЗАГАЛЬНОЇ СЕРЕДНЬОЇ ОСВІТИ
Authors: Швардак М. В.
Published: May 2021

У статті уточнено поняття «лідер», «лідерство», «лідерський потенціал». Центральною дефініцією дослідження є «технологія лідерства», яка трактується автором як сукупність знань про лідерство, його форми, концепції та стилі, а також послідовність етапів формування та розвитку в керівника лідерського потенціалу. Технологія лідерства у даному дослідженні розглядається в умовах сучасного закладу загальної середньої освіти. З’ясовано розбіжності між керівництвом та лідерством, керівником та лідером. Аналіз науково-педагогічної літератури з проблеми дав можливість з’ясувати, що традиційно виділяють дві форми лідерства: формальне та неформальне. Схарактеризовано такі стилі лідерства: ідеалістичний, навчаючий, товариський, демократичний, амбіціозний та авторитарний. З’ясовано, що станом на сьогодні ефективними в умовах закладу освіти вважаються концепції харизматичного лідерства, трансформаційного лідерства та лідерства в управлінні командою. Визначено першорядні лідерські якості. Серед них: організаторські здібності, авторитетність, активність, рішучість, упевненість у собі, асертивність, сила волі, гострий розум, розвинене почуття інтуїції, здатність до співпраці, стійкість до стресу, вміння слухати інших, бути приємним співрозмовником, оригінальність, рефлексивність, уміння психологічно грамотно впливати на ситуацію в колективі. З’ясовано, що розвиток лідерського потенціалу в керівників закладів загальної середньої освіти неможливий шляхом виключно інформування, адже передбачає відповідне ставлення та поведінку особистості. Тому програми навчання з розвитку лідерства мають бути практично-орієнтовані. Виділено основні форми розвитку лідерських якостей. Розроблено алгоритм розвитку лідерського потенціалу в керівників закладів загальної середньої освіти. Синтезовано типові помилки лідера.
ВИКОРИСТАННЯ ІННОВАЦІЙНИХ ПЕДАГОГІЧНИХ ТЕХНОЛОГІЙ У ЗАГАЛЬНОВІЙСЬКОВІЙ ПІДГОТОВЦІ МАЙБУТНІХ ОФІЦЕРІВ-ПРИКОРДОННИКІВ
Authors: Казєв О. В. , Овчар М. М. , Кошельник І. В.
Published: May 2021

Стаття присвячена аналізу питань вищої військової освіти. У цій загальній проблемі виділено питання загальновійськової підготовки майбутніх фахівців прикордонного відомства. Завдання щодо захисту та охорони державного кордону в українському суспільстві покладені на прикордонне відомство. Зазначена відомча структура має тривалу історію розвитку, і має можливість здійснювати підготовку власних офіцерських кадрів в єдиному вищому військовому навчальному закладі прикордонної служби – Національній академії. Мета загальновійськової підготовки майбутніх офіцерів-прикордонників полягає у створенні системних знань, умінь та навичок щодо вимог та потенціалу застосування бойової/спеціальної техніки; ведення бойових дій, виконання професійних завдань у мирний час та особливий період; щодо порядку дій у зоні різного виду зараження.

Основними завданнями загальновійськової підготовки майбутніх офіцерів-прикордонників є розуміння загальної характеристики сучасного бою. Пріоритетність цього завдання полягає в тому, що сучасній історичній епосі притаманна поява безлічі несистемних явищ та процесів, а це напряму вплинуло на загальні риси сучасного бою: висока напруженість; маневреність; короткочасність; максимальна швидкість; нові способи ведення бойових дій тощо. Виділено такі інноваційні технології, що варто застосовувати у загальновійськовій підготовці курсантів-прикордонників та які дають змогу виділити більше часу саме для практики: технології імітаційного моделювання; проектні технології, технології тренінгу та workshop, технологія індивідуального навчання, коучінг. Ефективність підготовки не матиме позитивної динаміки, якщо науково-педагогічні працівники будуть категоричними по відношенню до певної технології, методики, прийому або засобу.
Gender Dynamics in Islamic Law Perspective: Descriptive Study in Idaman Village, Banten
Authors: Tolkah Tolkah
Published: May 2021

Gender differences and cultural structures in the ideal village area classify the status of men and women. Islamic law has a different point of view in seeing gender status in Indonesian society. This study looks at the dynamics of gender in the village of ideal banten from the perspective of Islamic law. This study used a descriptive method with a qualitative approach, while the determination of the informants was purposvie sampling by considering traditional leaders, village heads and communities and finally data collection through primary and secondary. The results showed that gender dynamics inequality as a problem in the Islamic world, as well as the dark side of masculine-related behaviors cannot only be approached through the perspective of women alone.
EFEKTIVITAS WEBSITE UNITRI.AC.ID SEBAGAI MEDIA INFORMASI INTERNAL UNIVERSITAS
Authors: Ghofur Muchammad Abdul
Published: May 2021

Website merupakan salah satu hal terpenting yang ada di universitas karena kegunaannya sebagai media internal dalam konteks public relations atau Humas (Hubungan Masyarakat). Kerja Humas sebagai perekat komunikasi antar unit di dalam satu instansi merupakan keniscayaan sehingga seluruh karyawan dapat bekerja secara efektif. Tersedianya media internal seperit website akan membuat kerja Humas semakin efektif dan efisien. Di Universitas Tribhuwana Tunggadewi telah tersedia website dengan tampilan yang sudah diperbarui, tapi minim informasi di dalamnya. Penelitian ini bertujuan untuk mengetahui kebutuhan informasi dosen universitas, direpresentasikan oleh Kepala Program Studi yang banyak menemukan masalah dan mendapatkan solusi akademik, keuangan, kemahasiswaan, hingga hal-hal teknis di perguruan tinggi. Kebutuhan dosen yang tidak terpenuhi di website universitas akan menimbulkan permasalahan sekaligus beberapa solusi alternatif yang ditawarkan oleh masing-masing dosen tersebut sehingga dapat diambil langkah-langkah tindak lanjut oleh pihak universitas. Penelitian ini diharapkan menjadi salah satu dasar untuk membenahi website agar komunikasi internal universitas berjalan efektif.
İlkokul öğretmenlerinin kekemelik ve akran zorbalığına yönelik farkındalık düzeylerinin incelenmesi
Authors: ERİM Ahsen , AYDİN Ayşe
Published: May 2021

Okul çağı çocukları, vakitlerinin büyük bölümünü okullarında geçirmektedirler ve öğretmenler yaşamları üzerinde önemli bir rol oynamaktadır. Öğretmenlerin, kekemelik hakkında bilgili ve kekemeliğe yönelik açık bir tutum içinde olmalarının ise kekemeliği olan öğrencilerin maruz kalabilecekleri akran zorbalığını azaltma üzerinde merkez bir rolü olabileceğinden bahsedilmektedir. Bu çalışmanın amacı, ilkokul öğretmenlerinin kekemelik ve akran zorbalığına yönelik farkındalık düzeylerinin belirlenmesidir. Anket araştırma yöntemiyle yürütülen çalışmaya, Türkiye’nin farklı şehirlerinden 220 ilkokul öğretmeni katılmıştır. Verilerin toplanmasında ilgili alanyazın taranarak araştırmacılar tarafından hazırlanan bir anket kullanılmıştır. Kullanılan anket, 37 madde ve üç alt bölümden oluşmaktadır. Öğretmenlerin kekemeliğe yönelik farkındalık düzeylerinin, çeşitli değişkenlere göre olası farklılaşma durumunun incelenmesi için ise normal dağılım varsayımı karşılanmadığı için Mann Whitney U ve Kruskall Wallis H- Testleri kullanılmıştır. Ankette yer alan iki adet açık uçlu sorunun analizi için de içerik analizi yapılmıştır. Araştırmanın sonuçları, öğretmenlerin kekemelik ve akran zorbalığına yönelik farkındalık düzeylerinin artırılması gerektiğini göstermiştir. Ayrıca kekemelik hakkında araştırma yapan öğretmenlerin, araştırma yapmayan öğretmenlere ve kadın öğretmenlerin, erkek öğretmenlere kıyasla kekemeliğe yönelik farkındalık düzeylerinin anlamlı bir şekilde daha yüksek olduğu görülmüştür. Öğretmenlere yönelik kekemelik ve akran zorbalığı hakkında eğitim programlarının hizmet öncesi ve hizmet içi eğitim kapsamında uygulanmasının, okul çağı kekemelik yönetiminde olumlu etkileri olabileceği düşünülmektedir. Bu çalışmanın sonuçlarından yola çıkarak öğretmenlere yönelik düzenlenecek eğitim içeriklerinin; kekemeliğin nedenleri ve çok boyutlu doğası, kekemelik hakkında doğru bilinen yanlışlar, kekemeliği olan bireylere eşlik edebilen psikososyal sorunlar ve/veya DEHB nitelikleri, kekemeliği olan öğrencilere yönelik uygun sınıf stratejileri ve akran zorbalığı yönetimi başlıklarını içermesi önerilmektedir.