bluuebunny/crossref_metadata_2025 huggingface dataset:
Altered miRNA Signature of Developing Germ-cells in Infertile Patients Relates to the Severity of Spermatogenic Failure and Persists in Spermatozoa
Authors: Muñoz Xavier , Mata Ana , Bassas Lluís , Larriba Sara
Published: December 2015

The aim of this study was to assess the cellular miRNA expression behaviour in testes with spermatogenic failure (SpF). We performed a high-throughput screen of 623 mature miRNAs by a quantitative RT-qPCR-based approach in histologically well-defined testicular samples with spermatogenic disruption at different germ-cell stages, which revealed altered patterns of miRNA expression. We focussed on the differentially expressed miRNAs whose expression correlated with the number of testicular mature germ-cells and described the combined expression values of a panel of three miRNAs (miR-449a, miR-34c-5p and miR-122) as a predictive test for the presence of mature germ-cells in testicular biopsy. Additionally, we determined decreased cellular miRNA content in developing germ-cells of SpF testis; this was more noticeable the earlier the stage of germ-cell differentiation was affected by maturation failure. Furthermore, we showed that the miRNA expression profile in mature sperm from mild SpF patients was widely altered. Our results suggest that the cellular miRNA content of developed germ-cells depends heavily on the efficacy of the spermatogenic process. What is more, spermatozoa that have fulfilled the differentiation process still retain the dysregulated miRNA pattern observed in the developing SpF germ-cells. This altered miRNA molecular signature may have functional implications for the male gamete.
A20 regulates IL-1-induced tolerant production of CXC chemokines in human mesangial cells via inhibition of MAPK signaling
Authors: Luo Hongbo , Liu Yuming , Li Qian , Liao Lingjuan , Sun Ruili , Liu Xueting , Jiang Manli , Hu Jinyue
Published: December 2015

Chemokines and chemokine receptors are involved in the resolution or progression of renal diseases. Locally secreted chemokines mediated leukocyte recruitment during the initiation and amplification phase of renal inflammation. However, the regulation of chemokine induction is not fully understood. In this study, we found that IL-1 induced a significant up-regulation of CXC chemokines CXCL1, 2 and 8 at both mRNA and protein levels in human mesangial cells. The induction of chemokines was tolerant, as the pre-treatment of HMC with IL-1 down-regulated the induction of chemokines induced by IL-1 re-stimulation. IL-1 up-regulated the ubiquintin-editing enzyme A20. A20 over-expression down-regulated IL-1-induced up-regulation of chemokines and A20 down-regulation reversed chemokine inhibition induced by IL-1 pre-treatment, suggested that A20 played important roles in the tolerant production of chemokines. Unexpectedly, A20 over- expression inhibited the activation of ERK, JNK and P38, but did not inhibit the activation of NF-κB. In addition, both IL-1 treatment and A20 over-expression induced the degradation of IRAK1, an important adaptor for IL-1R1 signaling and A20 inhibition by RNA interference partly reversed the degradation of IRAK1. Taken together, IL-1-induced A20 negatively regulated chemokine production, suggesting that A20 may be an important target for the prevention and control of kidney inflammation.
Distinct X-chromosome SNVs from some sporadic AD samples
Authors: Gómez-Ramos A. , Podlesniy P. , Soriano E. , Avila J.
Published: December 2015

Sporadic Alzheimer disease (SAD) is the most prevalent neurodegenerative disorder. With the development of new generation DNA sequencing technologies, additional genetic risk factors have been described. Here we used various methods to process DNA sequencing data in order to gain further insight into this important disease. We have sequenced the exomes of brain samples from SAD patients and non-demented controls. Using either method, we found a higher number of single nucleotide variants (SNVs), from SAD patients, in genes present at the X chromosome. Using the most stringent method, we validated these variants by Sanger sequencing. Two of these gene variants, were found in loci related to the ubiquitin pathway (UBE2NL and ATXN3L), previously do not described as genetic risk factors for SAD.
Chikusetsu saponin IVa confers cardioprotection via SIRT1/ERK1/2 and Homer1a pathway
Authors: Duan Jialin , Yin Ying , Wei Guo , Cui Jia , Zhang Enhu , Guan Yue , Yan Jiajia , Guo Chao , Zhu Yanrong , Mu Fei , Weng Yan , Wang Yanhua , Wu Xiaoxiao , Xi Miaomiao , Wen Aidong
Published: December 2015

Hyperglycemia-induced reactive oxygen species (ROS) generation and Ca2+ overload contribute to the development of diabetic cardiomyopathy. In this study, we aimed to study the protective effects of Chikusetsu saponin IVa (CHS) from Aralia taibaiensis against hyperglycemia-induced myocardial injuries. Treatment of H9c2 cells with high glucose (HG) for 24 h resulted in a loss of cell viability and increase of ROS, LDH and Ca2+ levels and also induced cell apoptosis and those changes were all markedly reversed by the administration of CHS. In further studies, CHS dose-dependently increased the expression of Homer1a, ERK1/2 and SIRT1 in both H9c2 cells and rat primary cardiomyocytes. However, transfection of Homer1a-specific siRNA abolished the ability of CHS in controlling the ROS and Ca2+ homeostasis. Moreover, specific SIRT1 inhibitors or siRNA significantly suppressed the enhanced phosphorylation of ERK1/2 and expression of Homer1a induced by CHS as well as its cytoprotective effect. CHS induced Homer1a expression was also suppressed by siERK1/2. Additionally, results in diabetic mice also showed that CHS protected myocardium from I/R-introduced apoptosis by activating the SIRT1/ERK1/2/Homer1a pathway. These results demonstrated that CHS protected against hyperglycemia-induced myocardial injury through SIRT1/ERK1/2 and Homer1a pathway in vivo and in vitro.
A new approach for trace analysis of guanidine compounds in surface water with resorcinarene-based ion chromatography columns
Authors: Panahi Tayyebeh , Weaver Douglas J. , Lamb John D. , Harrison Roger G.
Published: December 2015

New stationary phase materials based on glutamic acid functionalized resorcinarenes bound to divinylbenzene macroporous resin are used to separate guanidine contaminants in surface water.
Using fluoro modified RNA aptamers as affinity ligands on magnetic beads for sensitive thrombin detection through affinity capture and thrombin catalysis
Authors: Hao Lihua , Zhao Qiang
Published: December 2015

RNA aptamer Toggle-25 was used as an affinity ligand on magnetic beads for thrombin detection following affinity capture and enzyme reaction.
Detection of sibutramine and phenolphthalein in functional foods using capillary electrophoresis
Authors: Wang Dan , Man Ranru , Shu Ming , Liu Huitao , Gao Yuan , Luan Feng
Published: December 2015

Detection of sibutramine and phenolphthalein in functional foods by using capillary electrophoresis.
Single crystal to single crystal [2+2] photoreactions in chloride and sulphate salts of 4-amino-cinnamic acid via solid-solution formation: a structural and kinetic study
Authors: d'Agostino Simone , Spinelli Floriana , Boanini Elisa , Braga Dario , Grepioni Fabrizia
Published: December 2015

SCSC [2+2] photodimerizationviathe formation of solid state solution is achieved in chloride and sulfate salts of 4-amino-cinnamic acid, and structural and kinetic analyses have been performed.
Organometallic chemistry meets crystal engineering to give responsive crystalline materials
Authors: Bacchi A. , Pelagatti P.
Published: December 2015

Like the meeting between the heroes Garibaldi and the King of Sardinia Vittorio Emanuele II led to United Italy, the meeting between organometallic chemistry and crystal engineering led to responsive crystalline materials.
Methyl and t-butyl group rotation in a molecular solid:1H NMR spin-lattice relaxation and X-ray diffraction
Authors: Beckmann Peter A. , Moore Curtis E. , Rheingold Arnold L.
Published: December 2015

We report solid state1H nuclear magnetic resonance spin-lattice relaxation experiments and X-ray diffractometry in 2-t-butyldimethylsilyloxy-6-bromonaphthalene.
Understanding the mechanism of CO2 capture by 1,3 di-substituted imidazolium acetate based ionic liquids
Authors: Mao James X. , Steckel Janice A. , Yan Fangyong , Dhumal Nilesh , Kim Hyung , Damodaran Krishnan
Published: December 2015

Efficient CO2 capture by ionic liquids needs a thorough understanding of underlying mechanisms of the CO2 interaction with ionic liquids, especially when it involves chemisorption.
Long term puzzles of the CH and CD energetics and related phenomena revisited; solutions sought through REMPI-photofragmentations of bromomethanes
Authors: Hafliðason Arnar , Wang Huasheng , Kvaran Ágúst
Published: December 2015

The use of REMPI in fundamental fragment analysis.
Two-dimensional electron gas at the LaAlO3/SrTiO3 inteface with a potential barrier
Authors: Stephanovich V. A. , Dugaev V. K. , Barnaś J.
Published: December 2015

We present a tight binding description of electronic properties of the interface between LaAlO3 (LAO) and SrTiO3 (STO). We show that depending on the potential strength, charge carriers (electrons or holes) may form an energy band which is localized at the interface and is within the band gaps of the constituent materials (LAO and STO).
Tuning surface grafting density of CeO2 nanocrystals with near- and supercritical solvent characteristics
Authors: Giroire B. , Slostowski C. , Marre S. , Aymonier C. , Aida T. , Hojo D. , Aoki N. , Takami S. , Adschiri T.
Published: December 2015

In this work, the solvent effect on the synthesis of CeO2 nanocrystals prepared in near- and supercritical alcohols is discussed.
Hydrolysis mechanisms of BNPP mediated by facial copper(ii) complexes bearing single alkyl guanidine pendants: cooperation between the metal centers and the guanidine pendants
Authors: Zhang Xuepeng , Liu Xueping , Phillips David Lee , Zhao Cunyuan
Published: December 2015

The inter-complex and intra-complex nucleophilic attacks by metal-bound hydroxide were investigated by considering the second coordination spheres.
Radiolabelling with isotopic mixtures of52g/55Mn(ii) as a straight route to stable manganese complexes for bimodal PET/MR imaging
Authors: Vanasschen Christian , Brandt Marie , Ermert Johannes , Coenen Heinz H.
Published: December 2015

Novel isotopic52g/55Mn(ii) complexes as basis for bimodal PET/MR imaging.
Controllable assembly, characterization and catalytic properties of a new Strandberg-type organophosphotungstate
Authors: Ma Hong-Xin , Du Jing , Zhu Zai-Ming , Lu Ting , Su Fang , Zhang Lan-Cui
Published: December 2015

A new Strandberg-type organophosphotungstate was assembled under hydrothermal conditions and displayed good fluorescence properties and catalytic activity.
Hydrothermal synthesis of bi-functional nanostructured manganese tungstate catalysts for selective oxidation
Authors: Li Xuan , Lunkenbein Thomas , Kröhnert Jutta , Pfeifer Verena , Girgsdies Frank , Rosowski Frank , Schlögl Robert , Trunschke Annette
Published: December 2015

The mechanism of C–H activation in selective oxidation reactions of short-chain alkane molecules over transition metal oxides is critically affected by the balance of acid–base and redox sites at the surface of the catalyst. Using the example of manganese tungstate we discuss how the relative abundance of these sites can be controlled via synthetic techniques. Phase-pure catalysts composed of the thermodynamic stable monoclinic MnWO4 phase have been prepared using hydrothermal synthesis. Variation of the initial pH value resulted in rod-shaped nano-crystalline MnWO4 catalysts composed of particles with varying aspect ratio. The synthesis products have been analysed using transmission electron microscopy, X-ray diffraction, infrared, and photoelectron spectroscopy. In situ Raman spectroscopy was used to investigate the dissolution–re-crystallization processes occurring under hydrothermal conditions. Ethanol oxidation was applied to probe the surface functionalities in terms of acid–base and redox properties. Changes in the aspect ratio of the primary catalyst particles are reflected in the product distribution induced by altering the fraction of acid–base and redox sites exposed at the surface of the catalysts in agreement with the proposed mechanism of particle growth by re-crystallization during ageing under hydrothermal conditions.
Keto analogue and amino acid supplementation and its effects on ammonemia and performance under thermoneutral conditions
Authors: Camerino Saulo Rodrigo Alves e Silva , Lima Rafaela Carvalho Pereira , França Thássia Casado Lima , Herculano Edla de Azevedo , Rodrigues Daniela Souza Araújo , Gouveia Marcos Guilherme de Sousa , Cameron L. C. , Prado Eduardo Seixas
Published: December 2015

Keto analogue and amino acid supplementation decreases ammonemia during exercise without affecting performance.
Multifunctional β-amino alcohols as bio-based amine curing agents for the isocyanate- and phosgene-free synthesis of 100% bio-based polyhydroxyurethane thermosets
Authors: Blattmann H. , Mülhaupt R.
Published: December 2015

Novel 100% bio-based NIPU thermosets by employing bio-based epoxy resin feedstocks as raw material for cyclic carbonate monomers and amine curing agents.
Build to understand: synthetic approaches to biology
Authors: Wang Le-Zhi , Wu Fuqing , Flores Kevin , Lai Ying-Cheng , Wang Xiao
Published: December 2015

In this review we discuss how synthetic biology facilitates the task of investigating genetic circuits that are observed in naturally occurring biological systems.
Complementary HPLC-ICP-MS and synchrotron X-ray absorption spectroscopy for speciation analysis of chromium in tobacco samples
Authors: Cuello Susana , Entwisle John , Benning Jocelyn , Liu Chuan , Coburn Steven , McAdam Kevin G. , Braybrook Julian , Goenaga-Infante Heidi
Published: December 2015

This paper provides first quantitative speciation data for chromium in tobacco and tobacco smoke by using complementary HLPC-ICP-MS and XANES.
Atomic spectrometry update – a review of advances in environmental analysis
Authors: Butler Owen T. , Cairns Warren R. L. , Cook Jennifer M. , Davidson Christine M.
Published: December 2015

This review covers advances in the analysis of air, water, plants, soils and geological materials by a range of atomic spectrometric techniques including atomic emission, absorption, fluorescence and mass spectrometry.
Cell cycle related genes up-regulated in human colorectal development predict the overall survival of late-stage colorectal cancer patients
Authors: An Ning , Yang Xue , Zhang Yueming , Shi Xiaoyu , Yu Xuexin , Cheng Shujun , Zhang Kaitai , Wang Guiqi
Published: December 2015

The expression profile of human colorectal developing tissues in 4 sequential stages was accomplished, and V probes and A probes were obtained based on differential expression patterns during embryonic development and carcinogenesis.
Binding mechanisms of 1,4-dihydropyridine derivatives to L-type calcium channel Cav1.2: a molecular modeling study
Authors: Xu Lei , Li Dan , Tao Li , Yang Yanling , Li Youyong , Hou Tingjun
Published: December 2015

L-type Ca2+channels (LTCCs), the heteromultimeric proteins, are associated with electrical signaling and provide the key link between electrical signals and non-electrical processes.
Preparation of mesoporous TiO2–C composites as an advanced Ni catalyst support for reduction of 4-nitrophenol
Authors: Gao Wenjun , Li Wei , Xue Zhaoteng , Pal Manas , Liu Yong , Wang Chun , Wang Jinxiu , Wang Shuai , Wan Xiaoyue , Liu Yang , Zhao Dongyuan
Published: December 2015

Ordered mesoporous Ni/TiO2–C composites with highly dispersed nickel and TiO2 nanoparticles have been synthesized via a multi-component co-assembly method.
Detection of quantum well induced single degenerate-transition-dipoles in ZnO nanorods
Authors: Ghosh Siddharth , Ghosh Moumita , Seibt Michael , Mohan Rao G.
Published: December 2015

We demonstrate a basal stacking fault induced localised quantum well with a single degenerate-transition-dipole in undoped ZnO nanorods using defocused optical wide-field microscopy.
The electronic and transport properties of two-dimensional conjugated polymer networks including disorder
Authors: Adjizian Jean-Joseph , Lherbier Aurélien , M.-M. Dubois Simon , Botello-Méndez Andrés Rafael , Charlier Jean-Christophe
Published: December 2015

Two-dimensional conjugated polymers exhibit electronic structures analogous to that of graphene with the peculiarity of π–π* bands which are fully symmetric. Here we report their electronic and transport properties in the presence of defects.
Zebrafish as a model system for characterization of nanoparticles against cancer
Authors: Evensen Lasse , Johansen Patrick L. , Koster Gerbrand , Zhu Kaizheng , Herfindal Lars , Speth Martin , Fenaroli Federico , Hildahl Jon , Bagherifam Shahla , Tulotta Claudia , Prasmickaite Lina , Mælandsmo Gunhild M. , Snaar-Jagalska Ewa , Griffiths Gareth
Published: December 2015

The zebrafish embryo enables characterization of nanoparticles against cancer in anin vivovertebrate model.
Shape control of inorganic nanoparticles from solution
Authors: Wu Zhaohui , Yang Shuanglei , Wu Wei
Published: December 2015

The controlled shapes of inorganic nanoparticles through diverse mechanisms in solution were discussed based on classical nucleation and growth theory.
Variable mechanism of nucleophilic substitution of P-stereogenic phosphoryl chloride with alkynyl metallic reagents
Authors: Yao Lan , Liu Li-Juan , Xu Zhong-Yuan , Nie Shao-Zhen , Xiao Xiao-Qing , Zhao Chang-Qiu
Published: December 2015

The variable mechanism for substitution of P-stereogenic phosphoryl chloride with alkynyl metallic reagents depends on temperature, stoichiometry of starting materials, and the structure of the nucleophilic reagent.
A stereo configuration-activity study of 3-iodo-4-(2-methylcyclohexyloxy)-6-phenethylpyridin-2(2H)-ones as potency inhibitors of HIV-1 variants
Authors: Wu Shaotong , Yin Qianqian , Zhao Liang , Fan Ningning , Tang Xiaowan , Zhao Jianxiong , Sheng Tao , Guo Ying , Tian Chao , Zhang Zhili , Xu Weisi , Liu Zhenming , Jiang Shibo , Ma Liying , Liu Junyi , Wang Xiaowei
Published: December 2015

The trans-(S, S)-enantiomer 2e turned out to be significantly more potent than its enantiomer 2d against wild-type and mutant strains with high selectivity indexes.
Nanocomposites of polymer brush and inorganic nanoparticles: preparation, characterization and application
Authors: Nie Genkuo , Li Guozhu , Wang Li , Zhang Xiangwen
Published: December 2015

We tackle in this review the use of a subset of polymer brushes (e.g., polyelectrolytes and polyampholytes) for the embedment of inorganic NPs to make composite surfaces/NPs with specific functions.
Efficient synthesis and photovoltaic properties of highly rigid perylene-embedded benzothiazolyls
Authors: Chen Runfeng , Zheng Chunhua , Li Cong , Li Huanhuan , Wang Zhixiang , Tang Yuting , Jiang Hongji , Tan Zhanao , Huang Wei
Published: December 2015

Perylene-embedded benzothiazolyls, designed by 2D-fusing of dithienylbenzothiadiazoles, have been synthesized and characterized as new electron-accepting building-blocks for organic photovoltaic applications.
SET-LRP of NIPAM in water via in situ reduction of Cu(ii) to Cu(0) with NaBH4
Authors: Gavrilov Mikhail , Zerk Timothy J. , Bernhardt Paul V. , Percec Virgil , Monteiro Michael J.
Published: December 2015

The direct and quantitative reduction of the air-stable Cu(ii)Br2/Me6TREN to Cu(0) by NaBH4 represents a new method for the aqueous single electron transfer-living radical polymerization (SET-LRP) of water soluble polymers.
Functionalization of reduced graphene oxide with axially-coordinated metal-porphyrins: facile syntheses and temporally-dependent nonlinear optical properties
Authors: Wang Aijian , Song Jingbao , Jia Ding , Yu Wang , Long Lingliang , Song Yinglin , Cifuentes Marie P. , Humphrey Mark G. , Zhang Long , Shao Jianda , Zhang Chi
Published: December 2015

Reduced graphene oxide-tin porphyrin nanohybrids with good dispersibility have been prepared, which exhibited large optical nonlinearity due to a combination of mechanisms.
Excess-electron-induced C–C bond formation in transformation of carbon dioxide
Authors: Ma Fang , Miao Tao , Zhou Zhong-Jun , Xu Hong-Liang
Published: December 2015

We presented a new fixation method of CO2 through excess-electron-induced C–C bond. For the reaction of CO2 and C6H6, they can produce one H2 and phthalic acid radical via two H-atom elimination, with the help of the hydrogen bond complex.
Long term effects of substrate stiffness on the development of hMSC mechanical properties
Authors: Xu Qinwei , Li Cheng , Kang Yuejun , Zhang Yilei
Published: December 2015

Micropipette aspiration of hMSCs cultured on different PDMS substrates showed that cells aligned their mechanical properties with the substrate stiffness and cell moduli always displayed a non-monotonic trend along culture time.
Radioprotective effects of active compounds of Acanthopanax senticosus from the Lesser Khingan Mountain range in China
Authors: Song Wei , Shi Jinming , Baranenko Denis , Jing Jing , Lu Weihong
Published: December 2015

Bioactive compounds extracted from wildAcanthopanax senticosusshowed radioprotective effects throughin vitroantioxidant activities and suppression of radiation injury in mice.
Comparative study of dry-mixing and wet-mixing activated carbons prepared from waste printed circuit boards by NaOH activation
Authors: Kan Yujiao , Yue Qinyan , Gao Baoyu , Li Qian
Published: December 2015

Two activated carbons have been produced from waste printed circuit boards by NaOH by two methods, dry-mixing and wet-mixing. The carbon prepared by dry-mixing is named as AC. The carbon prepared by wet-mixing is named as WAC.
Plasmonic absorption activated trapping and assembling of colloidal crystals with non-resonant continuous gold films
Authors: Kang Zhiwen , Chen Jiajie , Wu Shu-Yuen , Ho Ho-Pui
Published: December 2015

Here we report the realization of trapping and assembly of colloidal crystals on continuous gold thin films based on the combined effect of thermophoresis and thermal convection associated with plasmonic optical heating.
SnSb–ZnO composite materials as high performance anodes for lithium-ion batteries
Authors: Li Yongliang , Zhang Wei , Cai Huihua , Wang Jingwei , Ren Xiangzhong , Zhang Peixin
Published: December 2015

The addition of ZnO significantly improved the cycling performance and rate capability of SnSb alloy anode material.
A new and facile strategy for the one-pot fabrication of luminescent gold nanoclusters and their prospective application
Authors: Sinha Tanur , Ahmaruzzaman M.
Published: December 2015

Allium cepa L. peel, a common household waste material mediated fabrication of luminescent gold nanoclusters.
Lattice shearing in nano-grained graphene sheets: a molecular dynamics simulation
Authors: Yang Zhi , Huang Yuhong , Ma Fei , Miao Yaping , Bao Hongwei , Xu Kewei , Chu Paul K.
Published: December 2015

A set of nano-grained graphene models are established and molecular dynamics simulations are conducted to investigate mechanical deformation in the vicinity of grain boundaries under tensile loading.
Solidified SNEDDS of loratadine: formulation using hydrophilic and hydrophobic grades of Aerosil®, pharmacokinetic evaluations and in vivo–in silico predictions using GastroPlus™
Authors: Verma Samridhi , Singh Sandeep Kumar , Verma Priya Ranjan Prasad
Published: December 2015

Hydrophilic and hydrophobic grades of Aerosil® were employed to develop solid-SNEDDS of loratadine and evaluated for their influence on powder, physicochemical and biopharmaceutical properties.
Allantoin-loaded porous silica nanoparticles/polycaprolactone nanofiber composites: fabrication, characterization, and drug release properties
Authors: Ke Ma , Wahab Jatoi Abdul , Hyunsik Bang , Song Kyung-Hun , Lee Jung Soon , Gopiraman Mayakrishnan , Kim Ick Soo
Published: December 2015

The development of biocompatible nanocomposites for biomedical applications such as drug release has attracted increasing attention in recent years.
Theoretical insights into structure, bonding, reactivity and importance of ion-pair interactions in Kirby's tetrafluoroboric acid salts of twisted amides
Authors: Pandey Krishna K.
Published: December 2015

The hydrolysis of amide 1 is more exothermic and is more favorable than amides 2 and 3 with bridgehead methyl.
Characteristics of ultrasonication assisted assembly of gold nanoparticles in hydrazine reduced graphene oxide
Authors: Dave Kashyap , Park Kyung Hee , Dhayal Marshal
Published: December 2015

Graphene gold composites were synthesized by ultrasonication assisted in situ reduction of diffused gold chloride within hydrazine reduced graphene oxide sheets without surface modification or functionalization with organic molecules.
A nano-scale probing system with a gold nano-dot array for measurement of a single biomolecular interaction force
Authors: Kim Sung Joo , Seo Jeong Hyun , Lee Jin Woo , Cho Dong-Woo , Cha Hyung Joon , Moon Wonkyu
Published: December 2015

A new nano-scale probing system was proposed and developed to measure and analyze the interaction force between biomolecules at the single molecular level.
All-solution-processed, flexible thin-film transistor based on PANI/PETA as gate/gate insulator
Authors: Hong Jin-Yong , Yoon Dai Gun , Chin Byung Doo , Kim Sung Hyun
Published: December 2015

An all-solution processed flexible thin-film transistor based on a PANI/PETA gate/gate insulator exhibited higher mobility than the device with a Si/SiO2 gate/gate insulator because of large crystalline domains in the transition region.
A novel blue light pumped yellow-emitting phosphor RbZnPO4:Dy3+with satisfactory color tuning and thermal properties for high-power warm white light emitting diodes
Authors: Zhu Ge , Xin Shuangyu
Published: December 2015

Novel yellow phosphor RbZnPO4:Dy3+with satisfactory color tuning and thermal properties for high-power white LEDs.
The positive effect of anatase and rutile on the brookite-photocatalyzed degradation of phenol
Authors: Luo Bangde , Li Zhen , Xu Yiming
Published: December 2015

In this study, the biphase effect of brookite with anatase or rutile has been reinvestigated by using phenol degradation in aqueous solution as a model reaction.
Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?
Authors: Stals Patrick J. M. , Cheng Chi-Yuan , van Beek Lotte , Wauters Annelies C. , Palmans Anja R. A. , Han Songi , Meijer E. W.
Published: December 2015

A library of water-soluble dynamic single-chain polymeric nanoparticles (SCPN) was prepared using a controlled radical polymerisation technique followed by the introduction of functional groups, including probes at targeted positions.
Radical transfer in E. coli ribonucleotide reductase: a NH2Y731/R411A-α mutant unmasks a new conformation of the pathway residue 731
Authors: Kasanmascheff Müge , Lee Wankyu , Nick Thomas U. , Stubbe JoAnne , Bennati Marina
Published: December 2015

A new conformation of theE. coliRNR pathway residue 731 was trapped during long-range radical transfer across the αβ subunit interface.
Tethered tertiary amines as solid-state n-type dopants for solution-processable organic semiconductors
Authors: Russ Boris , Robb Maxwell J. , Popere Bhooshan C. , Perry Erin E. , Mai Cheng-Kang , Fronk Stephanie L. , Patel Shrayesh N. , Mates Thomas E. , Bazan Guillermo C. , Urban Jeffrey J. , Chabinyc Michael L. , Hawker Craig J. , Segalman Rachel A.
Published: December 2015

Tertiary amines covalently tethered to electron-deficient aromatic molecules by alkyl spacers enable solid-state n-doping.
Electrohydrodynamic manipulation of particles adsorbed on the surface of a drop
Authors: Amah Edison , Shah Kinnari , Fischer Ian , Singh Pushpendra
Published: December 2015

A method for concentrating particles at the poles or the equator of a drop and for moving them between the poles and the equator by selecting a suitable frequency of the electric field, and for forming Janus drops by separating particles with different dielectric properties on the surface of the drop.
SiO2/TiO2based hollow nanostructures as scaffold layers and Al-doping in the electron transfer layer for efficient perovskite solar cells
Authors: Yun Juyoung , Ryu Jaehoon , Lee Jungsup , Yu Haejun , Jang Jyongsik
Published: December 2015

Perovskite solar cells based on SiO2/TiO2hollow nanoparticles as scaffold layers and Al-TiO2compact layers exhibited an efficiency of 14.7%.
Centimeter-sized biomimetic bone constructs fabricated via CBD-BMP2-collagen microcarriers and BMSC-gelatin microspheres
Authors: Kou Depeng , Du Mingchun , Hou Xianglin , Chen Bing , Li Xing , Fang Yongxiang , Zhao Yannan , Wang Hong , Wang Ling , Dai Jianwu
Published: December 2015

The cell-culture modules and function-control modules could be easily assembled into the aimed tissue in “bottom-up” approaches.
Effect of solvent, pH and metal ions on the self-assembly process and optical properties of an A–π–D–π–A type triphenylamine carboxylic acid derivative
Authors: Kong Lin , Liu Yun , Wang Hui , Tian Xiao-he , Chen Qi-yu , Tian Yu-peng , Li Sheng-li , Xue Zhao-ming , Yang Jia-xiang
Published: December 2015

The effect of solvent, pH and metal ion on the morphology and optical properties of a carboxylic-acid derivative was researched.
Zero‐voltage‐transition bridgeless power factor correction rectifier with soft‐switched auxiliary circuit
Authors: Hua Chih‐Chiang , Fang Yi‐Hsiung , Huang Chin‐Hsiung
Published: December 2015

This study presents a zero‐voltage‐transition (ZVT) bridgeless power factor correction (PFC) rectifier, which uses an auxiliary circuit with a transformer to achieve soft‐switching for the main power switches. With the auxiliary circuit, the main switches can be ZVT turned‐on without any additional voltage or current stresses. In addition, the auxiliary switch is turned‐off with zero‐current switching. Therefore, the switching loss of all power switches is reduced, and the overall rectifier efficiency is improved. The circuit topology, operation analysis and the components selection of the proposed rectifier are described in detail. Finally, a laboratory prototype of 700 W is implemented and tested to verify the performance of the proposed PFC rectifier.
Insect biofuel cell using an electrode with gold nanoparticles deposited by sputtering
Authors: Shoji Kan , Akiyama Yoshitake , Suzuki Masato , Nakamura Nobuhumi , Ohno Hiroyuki , Morishima Keisuke
Published: December 2015

A high‐stability living battery that uses a metallic catalyst for glucose oxidation instead of enzymes is investigated. In this battery, glucose in insect haemolymph is oxidised by a gold nanoparticle (AuNP)‐modified electrode, which is utilised as the anode of the battery. The AuNP‐modified electrode was fabricated by sputtering gold onto a carbon cloth in a low‐vacuum state. First, the oxidation performance values of glucose were evaluated and the oxidation current of glucose was obtained by the AuNP‐modified electrode from cockroach haemolymph (CHL). Then, the electrocatalytic stability of the AuNP‐modified electrode was compared with an enzymatic electrode. Furthermore, a glucose biofuel cell consisting of the AuNP‐modified electrode and a bilirubin oxidase‐modified electrode was constructed; the respective power densities obtained from 100 mM glucose solution and CHL were 22.4 and 15.1 µW/cm2, respectively. It is concluded that AuNPs are a useful catalyst for living batteries.
Development of the negative ion beams relevant to ITER and JT-60SA at Japan Atomic Energy Agency
Authors: Hanada M. , Kojima A. , Tobari H. , Nishikiori R. , Hiratsuka J. , Kashiwagi M. , Umeda N. , Yoshida M. , Ichikawa M. , Watanabe K. , Yamano Y. , Grisham L. R.
Published: December 2015

In order to realize negative ion sources and accelerators to be applicable to International Thermonuclear Experimental Reactor and JT-60 Super Advanced, a large cesium (Cs)-seeded negative ion source and a multi-aperture and multi-stage electric acceleration have been developed at Japan Atomic Energy Agency (JAEA). Long pulse production and acceleration of the negative ion beams have been independently carried out. The long pulse production of the high current beams has achieved 100 s at the beam current of 15 A by modifying the JT-60 negative ion source. The pulse duration time is increased three times longer than that before the modification. As for the acceleration, a pulse duration time has been also extended two orders of magnitudes from 0.4 s to 60 s. The developments of the negative ion source and acceleration at JAEA are well in progress towards the realization of the negative ion sources and accelerators for fusion applications.
Prediction in projection
Authors: Garland Joshua , Bradley Elizabeth
Published: December 2015

Prediction models that capture and use the structure of state-space dynamics can be very effective. In practice, however, one rarely has access to full information about that structure, and accurate reconstruction of the dynamics from scalar time-series data—e.g., via delay-coordinate embedding—can be a real challenge. In this paper, we show that forecast models that employ incomplete reconstructions of the dynamics—i.e., models that are not necessarily true embeddings—can produce surprisingly accurate predictions of the state of a dynamical system. In particular, we demonstrate the effectiveness of a simple near-neighbor forecast technique that works with a two-dimensional time-delay reconstruction of both low- and high-dimensional dynamical systems. Even though correctness of the topology may not be guaranteed for incomplete reconstructions like this, the dynamical structure that they do capture allows for accurate predictions—in many cases, even more accurate than predictions generated using a traditional embedding. This could be very useful in the context of real-time forecasting, where the human effort required to produce a correct delay-coordinate embedding is prohibitive.
The sheath effect on the floating harmonic method
Authors: Lee Jaewon , Kim Kyung-Hyun , Chung Chin-Wook
Published: December 2015

The floating harmonic method biases sinusoidal voltage to a probe sheath, and as its response, harmonic currents can be obtained. These currents can be used to determine the plasma parameters. However, different shapes of probes have different shapes of sheaths that can affect the diagnostic results. However, no research has been done on the sheath effect on the floating harmonic method. Therefore, we investigate the effect of the sheath during floating harmonic diagnostics by comparing cylindrical and planar probes. While the sinusoidal voltages were applied to a probe, because the sheath oscillated, the time variant ion current and their harmonic currents were added to the electron harmonic currents. In the floating harmonic method, the harmonic currents are composed of only the electron harmonic currents. Therefore, the ion harmonic currents affect the diagnostic results. In particular, the electron temperature obtained by the small probe tip was higher than that of the large probe tip. This effect was exacerbated when the ratio of the probe tip radius to the sheath length was smaller.
Si quantum dots in silicon nitride: Quantum confinement and defects
Authors: Goncharova L. V. , Nguyen P. H. , Karner V. L. , D'Ortenzio R. , Chaudhary S. , Mokry C. R. , Simpson P. J.
Published: December 2015

Luminescence of amorphous Si quantum dots (Si QDs) in a hydrogenated silicon nitride (SiNx:H) matrix was examined over a broad range of stoichiometries from Si3N2.08 to Si3N4.14, to optimize light emission. Plasma-enhanced chemical vapor deposition was used to deposit hydrogenated SiNx films with excess Si on Si (001) substrates, with stoichiometry controlled by variation of the gas flow rates of SiH4 and NH3 gases. The compositional and optical properties were analyzed by Rutherford backscattering spectroscopy, elastic recoil detection, spectroscopic ellipsometry, photoluminescence (PL), time-resolved PL, and energy-filtered transmission electron microscopy. Ultraviolet-laser-excited PL spectra show multiple emission bands from 400 nm (3.1 eV) to 850 nm (1.45 eV) for different Si3Nx compositions. There is a red-shift of the measured peaks from ∼2.3 eV to ∼1.45 eV as Si content increases, which provides evidence for quantum confinement. Higher N content samples show additional peaks in their PL spectra at higher energies, which we attribute to defects. We observed three different ranges of composition where Tauc band gaps, PL, and PL lifetimes change systematically. There is an interesting interplay of defect luminescence and, possibly, small Si QD luminescence observed in the intermediate range of compositions (∼Si3N3.15) in which the maximum of light emission is observed.
Ultrafast vibrational dynamics of the DNA backbone at different hydration levels mapped by two-dimensional infrared spectroscopy
Authors: Guchhait Biswajit , Liu Yingliang , Siebert Torsten , Elsaesser Thomas
Published: December 2015

DNA oligomers are studied at 0% and 92% relative humidity, corresponding to N < 2 and N > 20 water molecules per base pair. Two-dimensional (2D) infrared spectroscopy of DNA backbone modes between 920 and 1120 cm−1 maps fluctuating interactions at the DNA surface. At both hydration levels, a frequency fluctuation correlation function with a 300 fs decay and a slow decay beyond 10 ps is derived from the 2D lineshapes. The fast component reflects motions of DNA helix, counterions, and water shell. Its higher amplitude at high hydration level reveals a significant contribution of water to the fluctuating forces. The slow component reflects disorder-induced inhomogeneous broadening.
Vibrational corrections to the second hyperpolarizabilities of AlnPn clusters
Authors: Feitoza Luan , Silveira Orlando , Castro Marcos A. , Leão Salviano A. , Fonseca Tertius L.
Published: December 2015

In this work, we report results of vibrational corrections to the second hyperpolarizabilities of Al2P2, Al3P3, Al4P4, Al6P6, and Al9P9 clusters. The vibrational corrections were calculated through the perturbation theoretic method of Bishop and Kirtman and also using a variational methodology at the second order Møller-Plesset perturbation theory level with the aug-cc-pVDZ basis set. Results show that the vibrational corrections are important, accounting for more than half of the corresponding electronic second hyperpolarizabilities at the static limit. Comparisons between results obtained through both methods show very good agreements for the terms [α2] and [μβ] but significant differences for the term [μ2α]. Dynamic vibrational corrections to the second hyperpolarizabilities related to the dc-second harmonic generation, intensity dependent refractive index, and dc-Kerr nonlinear optical processes are also reported.
Wide bandwidth instantaneous radio frequency spectrum analyzer based on nitrogen vacancy centers in diamond
Authors: Chipaux M. , Toraille L. , Larat C. , Morvan L. , Pezzagna S. , Meijer J. , Debuisschert T.
Published: December 2015

We propose an original analog method to perform instantaneous and quantitative spectral analysis of microwave signals. An ensemble of nitrogen-vacancy (NV) centers held in a diamond plate is pumped by a 532 nm laser. Its photoluminescence is imaged through an optical microscope and monitored by a digital camera. An incoming microwave signal is converted into a microwave field in the area of the NV centers by a loop shaped antenna. The resonances induced by the magnetic component of that field are detected through a decrease of the NV centers photoluminescence. A magnetic field gradient induces a Zeeman shift of the resonances and transforms the frequency information into spatial information, which allows for the simultaneous analysis of the microwave signal in the entire frequency bandwidth of the device. The time dependent spectral analysis of an amplitude modulated microwave signal is demonstrated over a bandwidth of 600 MHz, associated to a frequency resolution of 7 MHz , and a refresh rate of 4 ms. With such integration time, a field of a few hundreds of μW can be detected. Since the optical properties of NV centers can be maintained even in high magnetic field, we estimate that an optimized device could allow frequency analysis in a range of 30 GHz, only limited by the amplitude of the magnetic field gradient. In addition, an increase of the NV centers quantity could lead both to an increase of the microwave sensitivity and to a decrease of the minimum refresh rate down to a few μs.
Fabrication and single-electron-transfer operation of a triple-dot single-electron transistor
Authors: Jo Mingyu , Uchida Takafumi , Tsurumaki-Fukuchi Atsushi , Arita Masashi , Fujiwara Akira , Ono Yukinori , Nishiguchi Katsuhiko , Inokawa Hiroshi , Takahashi Yasuo
Published: December 2015

A triple-dot single-electron transistor was fabricated on silicon-on-insulator wafer using pattern-dependent oxidation. A specially designed one-dimensional silicon wire having small constrictions at both ends was converted to a triple-dot single-electron transistor by means of pattern-dependent oxidation. The fabrication of the center dot involved quantum size effects and stress-induced band gap reduction, whereas that of the two side dots involved thickness modulation because of the complex edge structure of two-dimensional silicon. Single-electron turnstile operation was confirmed at 8 K when a 100-mV, 1-MHz square wave was applied. Monte Carlo simulations indicated that such a device with inhomogeneous tunnel and gate capacitances can exhibit single-electron transfer.
Radiation reaction effect on laser driven auto-resonant particle acceleration
Authors: Sagar Vikram , Sengupta Sudip , Kaw P. K.
Published: December 2015

The effects of radiation reaction force on laser driven auto-resonant particle acceleration scheme are studied using Landau-Lifshitz equation of motion. These studies are carried out for both linear and circularly polarized laser fields in the presence of static axial magnetic field. From the parametric study, a radiation reaction dominated region has been identified in which the particle dynamics is greatly effected by this force. In the radiation reaction dominated region, the two significant effects on particle dynamics are seen, viz., (1) saturation in energy gain by the initially resonant particle and (2) net energy gain by an initially non-resonant particle which is caused due to resonance broadening. It has been further shown that with the relaxation of resonance condition and with optimum choice of parameters, this scheme may become competitive with the other present-day laser driven particle acceleration schemes. The quantum corrections to the Landau-Lifshitz equation of motion have also been taken into account. The difference in the energy gain estimates of the particle by the quantum corrected and classical Landau-Lifshitz equation is found to be insignificant for the present day as well as upcoming laser facilities.
Hyperpolarizability dispersion measured for (CH3)2O
Authors: Couling Vincent W. , Shelton David P.
Published: December 2015

The third-order nonlinear-optical susceptibility of dimethyl ether, (CH3)2O, has been measured in the gas phase over the wavelength range 488 nm < λ < 1064 nm using the technique of gas-phase electric-field-induced second-harmonic generation with periodic phase matching and with N2 as the reference gas. Measurements span a range of temperature, which allows for separation of the temperature-independent second hyperpolarizability term from the temperature-dependent first hyperpolarizability term. The dispersion curves of the isotropically averaged first and second hyperpolarizabilities (β and γ) are deduced.
Self-organized titanium oxide nano-channels for resistive memory application
Authors: Barman A. , Saini C. P. , Sarkar P. , Satpati B. , Bhattacharyya S. R. , Kabiraj D. , Kanjilal D. , Dhar S. , Kanjilal A.
Published: December 2015

Towards developing next generation scalable TiO2-based resistive switching (RS) memory devices, the efficacy of 50 keV Ar+-ion irradiation to achieve self-organized nano-channel based structures at a threshold fluence of 5 × 1016 ions/cm2 at ambient temperature is presented. Although x-ray diffraction results suggest the amorphization of as-grown TiO2 layers, detailed transmission electron microscopy study reveals fluence-dependent evolution of voids and eventual formation of self-organized nano-channels between them. Moreover, gradual increase of TiO/Ti2O3 in the near surface region, as monitored by x-ray photoelectron spectroscopy, establishes the upsurge in oxygen deficient centers. The impact of structural and chemical modification on local RS behavior has also been investigated by current-voltage measurements in conductive atomic force microscopy, while memory application is manifested by fabricating Pt/TiO2/Pt/Ti/SiO2/Si devices. Finally, the underlying mechanism of our experimental results has been analyzed and discussed in the light of oxygen vacancy migration through nano-channels.
Replica-exchange-with-tunneling for fast exploration of protein landscapes
Authors: Yaşar Fatih , Bernhardt Nathan A. , Hansmann Ulrich H. E.
Published: December 2015

While the use of replica-exchange molecular dynamics in protein simulations has become ubiquitous, its utility is limited in many practical applications. We propose to overcome some shortcomings that hold back its use in settings such as multi-scale or explicit solvent simulations by integrating ideas of hybrid MC/MD into the replica-exchange protocol. This Replica-Exchange-with-Tunneling method is tested by simulating the Trp-cage protein, a system often used in molecular biophysics for testing sampling techniques.
Quartz-enhanced photoacoustic spectroscopy exploiting tuning fork overtone modes
Authors: Sampaolo A. , Patimisco P. , Dong L. , Geras A. , Scamarcio G. , Starecki T. , Tittel F. K. , Spagnolo V.
Published: December 2015

We report on a quartz-enhanced photoacoustic sensor (QEPAS) based on a custom-made quartz tuning fork (QTF) to operate in both the fundamental and the first overtone vibrational mode resonances. The QTF fundamental mode resonance falls at ∼3 kHz and the first overtone at ∼18 kHz. Electrical tests showed that the first overtone provides a higher quality factor and increased piezoelectric current peak values, with respect to the fundamental flexural mode. To evaluate the QTF acousto-electric energy conversion efficiency, we operated the QEPAS in the near-IR and selected water vapor as the target gas. The first overtone resonance provides a QEPAS signal-to-noise ratio ∼5 times greater with respect to that measured for the fundamental mode. These results open the way to employing QTF overtone vibrational modes for QEPAS based trace gas sensing.
Optimum distribution of thermal insulation material for constant insulation material volume or a given investment cost
Authors: Demir Hakan , Kemal Sevindir M. , Ağra Özden , Özgür Atayılmaz Ş. , Teke İsmail
Published: December 2015

Most of the recent studies based on the alternative energy sources and efficient use of energy due to the rapidly exhausting fossil energy sources. Insulation is one of the solutions applied to decrease heat losses or gains. Present studies require tedious iterations to achieve a solution for optimum distribution of thermal insulation material for the volumes confined with environments at different temperatures such as cold storages. In this study, a general analytical solution for the optimum distribution of thermal insulation material is given for the volumes confined with environments at different temperatures for a given investment cost or constant insulation material volume. Analytical solution technique given in this study eliminates the need for tedious iterations or using a specialized computer software, and can also be combined with economic analysis models to include effects of economical parameters such as fuel price, interest rate, etc. A case study is also given for explanation and application of suggested methodology for a room confined with environments at different temperatures. It is shown that optimum distribution of insulation material easily achieved by one step analytical solution technique.