bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Review: Safety and Efficacy Comparison between Sulfonylureas and Dipeptidyl Peptidase-4 Inhibitors as Second-Line Therapies in Type 2 Diabetes Mellitus
Authors: Gillani Syed Wasif , Moosvi Arzu F.
Published: April 2020

Background:

According to the World Health Organization (WHO), diabetes mellitus is considered the
7th leading cause of death as of 2016, while almost half of all deaths related to high blood glucose occur before
the age of 70. According to the 2019 American Diabetes Association’s (ADA) guidelines, metformin is the firstline
treatment for patients with Type 2 diabetes. Additional therapy is dependent on multiple patient-specific
factors, including cardiovascular risks, risk of hypoglycemia, metabolic changes, and cost. The objective of this
systematic review is to analyze variables of interest in Type 2 diabetes including fasting blood glucose (FBG),
post-prandial blood glucose (PPBG), hemoglobin A1c (HbA1c), microvascular complications, and cardiovascular
outcomes in order to determine the shift towards the newer class of medications for type 2 diabetes.

Methods:

A systematic review was conducted using ScienceDirect as the primary source of obtaining articles.
This review used PRISMA for reporting and GRACE for quality assessment of ten articles. The inclusion criteria
for the review consisted of patients who were on metformin therapy for a sufficient amount of time, as defined by
the trial’s protocol, and who were then initiated on either a sulfonylurea (glipizide or glimepiride) or a DPP-4
inhibitor (saxagliptin or linagliptin). The articles included in this review range from 2005-2019 that are written in
English only. Exclusion criteria for this systematic review were articles in which patients were not initially started
on metformin therapy, were diagnosed with Type 1 diabetes mellitus, and articles that were written in languages
other than English.

Results:

After filtering 50 studies, 10 were selected for meeting the criteria of variables of interest. Findings
suggested a significant reduction in fasting plasma glucose with 154 mg/dL + 4 mg/dL as baseline, decreasing to
132 mg/dL + 4 mg/dL with the use of glipizide & metformin combination. A similar pattern was presented with
the use of saxagliptin and metformin in combination, but changes were less significant than glipizide. However,
hypoglycemic events in patients who were taking glipizide with metformin versus saxagliptin with metformin;
13.4% of patients achieved HbA1c <7% without hypoglycemic events compared to 22.2% of the patients who
achieved an HbA1c of <7% without hypoglycemic events.

Conclusion:

Despite the higher efficacious characteristics of sulfonylureas in lowering HbA1c, due to its reported
hypoglycemic effects, DPP-4 inhibitors may be considered as a clinically stable choice for second-line therapy
after completing maximally tolerated doses of metformin. Sulfonylureas are considered better than DPP-4 inhibitors
for treatment in patients with cardiovascular disease history and hypoglycemia.
Cancer Stem Cell Niche in Colorectal Cancer and Targeted Therapies
Authors: Wang Hao , Cui Guihua , Yu Bo , Sun Meiyan , Yang Hong
Published: April 2020

Cancer stem cells (CSCs), also known as tumor-initiating cells, are a sub-population of tumor cells
found in many human cancers that are endowed with self-renewal and pluripotency. CSCs may be more resistant
to conventional anticancer therapies than average cancer cells, as they can easily escape the cytotoxic effects of
standard chemotherapy, thereby resulting in tumor relapse. Despite significant progress in related research, effective
elimination of CSCs remains an unmet clinical need. CSCs are localized in a specialized microenvironment
termed the niche, which plays a pivotal role in cancer multidrug resistance. The niche components of CSCs, such
as the extracellular matrix, also physically shelter CSCs from therapeutic agents. Colorectal cancer is the most
common malignancy worldwide and presents a relatively transparent process of cancer initiation and development,
making it an ideal model for CSC niche research. Here, we review recent advances in the field of CSCs
using colorectal cancer as an example to illustrate the potential therapeutic value of targeting the CSC niche.
These findings not only provide a novel theoretical basis for in-depth discussions on tumor occurrence, development,
and prognosis evaluation, but also offer new strategies for the targeted treatment of cancer.
Amano Lipase PS from Burkholderia cepacia- Evaluation of the Effect of Substrates and Reaction Media on the Catalytic Activity
Authors: Dulęba Jacek , Siódmiak Tomasz , Marszałł Michał Piotr
Published: April 2020

:

Lipases in the native or immobilized form have commonly been used as catalysts
in the chemical and pharmaceutical industry. One of the widely available enzyme
catalysts on the market is lipase from Burkholderia cepacia (BCLs), previously called
Pseudomonas cepacia (PCLs). This enzyme is applied, among others, in the stereoselective
acylation of molecules to achieve chiral pure enantiomers of drugs or their building
blocks. In this study, Amano lipase PS (APS-BCL), which is a commercial lipase from
Burkholderia cepacia (BC) was tested. The lipolytic activity of APS-BCL by hydrolysis
of vegetable oils and enantioselective activity of APS-BCL by the kinetic resolution of
(R,S)-1-phenylethanol with using isopropenyl acetate as an acyl donor were evaluated. An
effect of reaction media with different logP values (t-butyl methyl ether, dichloromethane,
diisopropyl ether, toluene, cyclohexane, n-hexane, isooctane and n-heptane) on the enantioselective activity of
lipase was also studied. The high value of the enantiomeric ratio (E =308.5) with the utilization of isopropenyl
acetate was achieved. Whereas, the best reaction medium turned out to be diisopropyl ether, C =47.9%, eep
=98%, ees =90%, after 24 h of incubation. Moreover, the influence of ω6/ω9 polyunsaturated fatty acids (PUFAs)
ratio in commercial (peanut, camelina, rape, pumpkin seed, walnut, sesame, avocado, rice, corn, black
cumin, hemp, safflower, grape seed) oils was investigated for the lipase activity. For the first time, the cut-off
limit of ω6/ω9 ratio was proposed. The ratio equal to or higher than 2.3 allows achieving higher lipolytic activity.
Feasibility of a Home-Based Tablet App for Dexterity Training in Multiple Sclerosis: Usability Study
Authors: van Beek Judith Jantine Willemijn , van Wegen Erwin Everardus Henri , Rietberg Marc Berend , Nyffeler Thomas , Bohlhalter Stephan , Kamm Christian Philipp , Nef Tobias , Vanbellingen Tim
Published: April 2020

Background

Persons with multiple sclerosis (MS) often experience dexterous difficulties during the performance of activities of daily living, such as fastening buttons, handling coins, or writing, therefore impacting their health-related quality of life. Mobile health (mHealth) solutions, such as tablet apps, may be used to train impaired dexterous skills. The feasibility of a tablet app–based dexterity home-based intervention in MS (TAD-MS) has not been explored yet in persons with MS.

Objective

The aim of this pilot study was to evaluate the feasibility and usability of home-based dexterity training with a tablet app in both persons with MS and healthy subjects.

Methods

A total of 9 persons with MS, aged 35-71 years, with an Expanded Disability Status Scale score between 2 and 7.5, performed the TAD-MS for 4 weeks, five times a week, with each training session lasting approximately 30 minutes. Participants’ impaired dexterity was measured by the Nine-Hole Peg Test. A total of 10 age-matched healthy subjects also tested and rated the usability of the app. Outcome measures were the adherence rate as well as usability measured by the System Usability Scale and a Custom User Engagement Questionnaire (CUEQ).

Results

High feasibility of the tablet app–based dexterity training program was shown by a 97% adherence rate to the training protocol (ie, mean 19.4/20 sessions completed, SD 0.8). High system usability scores (ie, mean 85.39%, SD 11.67) and overall high scores given in the CUEQ (ie, mean 8.2/10, SD 1.4) further point to high usability of the app. Neither demographic variables nor dexterity levels affected the use of the app.

Conclusions

This pilot study is the first to demonstrate high feasibility and usability of a new tablet app–based dexterity home-based training program among both persons with MS and healthy individuals. Whether this kind of training improves dexterity will need to be evaluated in a randomized controlled trial.
ANALISIS DESAIN PESAN PEMBELAJARAN BAHASA ARAB DALAM BUKU AJAR AL-‘ARABIYAH BAINA YADAIK LEVEL 1
Authors: Amien Saiful
Published: April 2020

ANALISIS DESAIN PESAN PEMBELAJARANBAHASA ARAB DALAM BUKU AJARAL-‘ARABIYAH BAINA YADAIK LEVEL 1Saiful Amien *)ABSTRACTThis paper is intended to describe the design analysis of the message in Arabic languagelearning textbook al-‘arabiyah baina yadaik. Issues to be discussed in this paper is Doesthe message have been designed to effectively and efficiently making it easier for learnersto understand and also discusses the advantages and disadvantages of the design of themessage. This analysis is based on the ability of humans to the realm of cognitive,affective and psychomotor. Therefore, educators should be able to provide learningconditions so that learners can achieve certain abilities learned. This is where the designof the learning message has a very important role, because the design of the learningmessage refers to the process of manipulating, or plan a pattern of signals or symbols(words, pictures) that can be used to provide learning conditions.Kata Kunci :Desain pesan pembelajaran, buku ajar al-’arabiyah baina yadaik
IMAM ZARKASYI DAN PEMBAHARUAN PESANTREN : REKONSTRUKSI ASPEK KURIKULUM, MENEJEMEN DAN ETIKA PENDIDIKAN
Authors: Nurhakim Moh.
Published: April 2020

Moh. Nurhakim
EVALUASI PROGRAM PENATAAN LINGKUNGAN BERMAIN BERBASIS HUBUNGAN SOSIAL ANAK DI RA ISTIQLAL JAKARTA PUSAT
Authors: Oktaria Renti
Published: April 2020

Renti Oktaria
Tendencies and potential of formation of common gas market in EEU
Authors: Tkachenko Marina F. , Allaiarova Nelya I.
Published: April 2020

The article discusses the relationship of the EEU member states in the gas sector. Based on the analysis of existing problems and contradictions, as well as the agreements reached in the EEU, an assessment is given of the prospects for the formation of a common gas market within the framework of a single economic space. The formation of a common gas market is seen as the key to ensuring its energy security and harmonious socioeconomic development of both suppliers and consumers of gas in EEU. The lack of a price model of the gas market, heterogeneity and incompatibility of the potential of national gas markets, the complexity of the unification of the rules of the market, export problems and other equally important issues determine the relevance of the study of the functioning and development of gas markets of the EEU member states. The aim of the work is to analyze and identify the main problems affecting the development of the gas industry in EEU. The results obtained in the course of the study suggest that the functioning of the common gas market of the EEU is possible in the conditions of achieving institutional homogeneity of national gas markets.
Design turbine blade Aeolian of vertical axis using laminated tin palm material using the finite element method
Authors: Martínez Manuel del Jesús , Castro Bermúdez Juan Dayal , Ortega Anillo Iván Darío
Published: April 2020

This work focuses in analyze the mechanical behavior of a vertical axis wind turbine Blade, which is constituted by a natural composite material of “Palma de Lata” and binder, constituents for which its mechanical properties are obtained through mechanical tests and literature references. This study was made under the wind conditions of the colombian “Cañon del Chicamocha”, whose aerodynamic loads (pressures) were obtained in previus studies. The Design was made base on the layers layout of the composite, from stress distribution analysis the critical regions to reinforce the blade were found. At last, the behavior of the reinforced Blade was verified, obtaining in the “Palma de Lata” laminated a feasible alternative to be used in the wind turbines design.
Ekstrover atau Introver : Klasifikasi Kepribadian Pengguna Twitter dengan Menggunakan Metode Support Vector Machine
Authors: Fikry Muhammad
Published: April 2020

Orang bertipe kepribadian ekstrover dan introver sama-sama menggunakan media sosial namun dalam tingkatan berbeda dan dengan alasan yang berbeda pula. Untuk dapat memahami seseorang, profil media sosialnya dapat digunakan sebagai sumber informasi. Pada penelitian ini, dilakukan klasifikasi kepribadian pengguna Twitter ke dalam kelas ekstrover atau introver dengan menggunakan metode Support Vector Machine (SVM). Profil pengguna Twitter diunduh melalui Twitter API sebanyak 46 akun. Pelabelan tipe kepribadian dilakukan berdasarkan hasil kuesioner kepribadian. Jumlah ciri yang digunakan sebanyak 17 ciri. Fungsi kernel yang digunakan adalah kernel RBF. Setelah melakukan seleksi parameter, dilakukan pelatihan untuk mendapatkan model terbaik. Model tersebut digunakan terhadap data uji. Dari hasil pengujian diketahui bahwa metode SVM dapat diterapkan untuk mengklasifikasi kepribadian ekstrover dan introver dengan akurasi sebesar 88,89%.
Identifikasi Sanitasi Rumah Sehat dengan Metode Multifactor Evaluation Process
Authors: Aldo Dasril
Published: April 2020

Penelitian ini bertujuan untuk memudahkan pihak Pusat Kesehatan Masyarakat dalam mengidentifikasi sanitasi rumah sehat. Sebagai pendukung dalam penelitian ini, akan menggunakan metode Multifactor Evaluation Process untuk melakukan analisis terhadap 20 data sanitasi yang didapatkan dari Pusat Kesehatan Masyarakat Seberang Padang dengan kriteria penilaian berupa Komponen Rumah, Sarana Sanitasi dan Prilaku Penghuni. Tahapan dari metode ini yaitu menetapkan bobot evaluasi masing-masing kriteria, menentukan nilai evaluasi faktor dan menghitung nilai total evaluasi sebagai nilai akhir dalam pengambilan keputusan. Dari pengujian terhadap 20 data sanitasi mendapatkan hasil berupa rumah tidak sehat 70% dan rumah sehat 30% dengan kecocokan 95% terhadap hasil yang didapatkan oleh pihak Pusat Kesehatan Masyarakat Seberang Padang. Dengan kecocokan tersebut maka metode ini cocok digunakan dalam identifikasi sanitasi rumah sehat. Kata Kunci: Identifikasi, Multifactor Evaluation Process, Sanitasi Rumah Sehat
Perancangan Sistem Informasi Penerimaan Negara Bukan Pajak Pada Kantor Kesehatan Pelabuhan Jambi
Authors: Aryani Lies
Published: April 2020

Di era globalisasi, Sistem Informasi telah digunakan oleh banyak  pihak, mulai dari tingkat organisasi, lembaga pendidikan hingga instansi baik swasta ataupun pemerintahan. Sistem Informasi memberikan pengaruh signifikan untuk membantu pihak manajemen dalam mengabil keputusan dan pembuatan laporan.Kantor Kesehatan Pelabuhan Jambi salah satu instansi pemerintahan yang memiliki sadar tentang informasi dan teknologi. Namun layanan administrasi penerimaan negara bukan pajak bagi pengunjung masih menggunakan sistem konvensional. Oleh karena itu, kegiatan administrasi yang lambat dan pengunjung masih kurang efektif. Masih ada kesalahan dalam memproses informasi dan laporan yang tidak tepat waktu.Diharapkan Sistem Informasi yang akan dirancang ini dapat mengoptimalkan kebutuhan Informasi di Kantor Kesehatan Pelabuhan Jambi.  Aplikasi yang didasarkan dari Visual basi.Net. ini bertujuan untuk mengelola waktu secara efisien, membuat data diproses secara akurat, dan efisien dalam laporan.
Gerenciamento de óleo residual - Proposta de intervenção para a cidade de Palmas - TO
Authors: Carvalho Aragão de Faria Ana Karla , Valdés Serra Juan Carlos
Published: April 2020

Um dos resíduos que mais contamina os recursos hídricos e causa grandes impactos ao sistema de tratamento de esgoto é o óleo de fritura residual, embora não seja do conhecimento de muitas pessoas e por isso não recebe a atenção devida da forma de armazenamento e correta destinação final deste resíduo. Este estudo tem como objetivo analisar o gerenciamento do óleo de fritura residual em âmbito nacional e internacional para chegar em uma proposta de intervenção na cidade de Palmas-TO. A estratégia utilizada para alcançar este objetivo é a utilização de pesquisa exploratória e métodos diretos dedutivos e de interpretação para chegar a um modelo ideal para a capital. Esta análise propende substanciar uma tomada de decisão na formulação do melhor modelo de gerenciamento do óleo de fritura residual de acordo com a realidade local da cidade de Palmas-TO.
Estudos taxonômicos do gênero Padina Adanson (Dictyotaceae-Phaeophyta) no litoral do Estado da Bahia, Brasil
Authors: Nunes José Marcos de Castro , De Paula Edison José
Published: April 2020

Este estudo faz parte de um levantamento florístico de algas marinhas bentônicas do estado da Bahia, desenvolvida pela Universidade Federal da Bahia. Não existe ainda no Brasil estudos taxonômicos que tratem exclusivamente deste gênero. Através da análise de caracteres morfo-anatômicos foram reconhecidos e ilustrados quatro táxons: Padinaantillarum (Kützing) Piccone, P. boergesenii Allender & Krafy, P. aff. gymnospora (Kützing) Sonder e P. sanctae-crucis Børgesen. Referência da descrição original, basiônimo, descrição morfológica, distribuição geográfica ao longo do litoral brasileiro, incluindo mapa e comentarios taxonômicos foram apresentados para cada táxon estudado. Chaves dicotômicas para identificaçãodas especies, bem como tabelas comparativas para cada táxon também são apresentadas.
Variações morfológicas do lóbulo em Lejeunea glaucescens Gott. (Lejeuneaceae, Jungermanniophyta)
Authors: Passos Bastos Cid José , Vilas Boas-Bastos Silvana B.
Published: April 2020

Foram estudados exemplares de Lejeunea glaucescens Gott. no sentido de serem estabelecidos padrões morfológicos objetivando melhor delimitar esse táxon, sendo identificados 10 padrões de variação nos lóbulos dos filídios. Análises desses padrões mostram que nãohá uma clara correlção com as condições ambientais.
Una subespecie nueva en el género Sideritis L. (Lamiaceae)
Authors: Crespo Villalba Manuel Benito , Solanas Ferrandiz José Luís , De la Torre García Antonio , Paya Mira Joaquín
Published: April 2020

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Introducción: El giro posmoderno
Authors: Rubio Carracedo José
Published: April 2020

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Voluntad de crear. Nietzsche o el arte contra la estética
Authors: Puelles Romero Luis
Published: April 2020

RESUMENEn el siglo XX ha sido el de constitución del mito Nietzsche. Entre los diversos factores que han intervenido en este proceso, destaca la caracterización de su filosofía según los modos del esteticismo del fin-del-siglo. Este trabajo analiza la dudosa pertinencia de esta adscripción partiendo de la observación de que lo que prima en la obra del alemán no es en primera instancia una filosofía estética sino más bien una teoría de la creación, una ética de la poiesis. Con este fin, se ensaya la ubicación de Nietzsche en el trayecto de la modernidad estética y se atiende a sus posiciones valorándolas en el marco general de una crítica de la cultura.PALABRAS CLAVEESTÉTICA-ESTETICISMO-POIESIS-MODERNIDADABSTRACTThe 20th century has created the myth of Nietzsche. Among the different factors intervening in this process, we can underline the characterization of his philosophy along the modes os fin-de-siècle aestheticism. This paper examines the doubtful atribution of this characterization. It argues that Nietzsche´s work should be defined in terms of a theory of creation, an ethics of poiesis, instead of a philosophy of aesthetics. Accordingly, I sitúate Nietzsche in the trajectory of aesthetic modernity and assess his work within a general critique of culture.KEYWORDSAESTHETICS-AESTHETICISM-POIESIS-MODERNITY
¿Qué relevancia pública tienen las convicciones privadas?
Authors: Arregui Jorge V.
Published: April 2020

RESUMENEl artículo discute la distinción tajante entre la moral pública y la privada establecida por Rawls o Rorty. Sostiene que, auqnue ha de defenderse la especificidad de la moralidad que rige las acciones públicas, tal distinción (que es un producto histórico fruto de una precisa tradición) no puede entenderse como tajante manteniendo que sólo algunas morales onicomprensivas privadas permiten afirmar el pluralismo en términos de valor moral, y no sólo de hecho includible; que las morales omnicomprensivas privadas actúan como límite de las actuaciones públicas; y que las convicciones personales pueden ejercer un papel estabilizador de la vida política.PALABRAS CLAVEPLURALISMO-MORAL PÚBLICA-CONVICCIONES PRIVADASABSTRACTThis papers questions the separation between private and public morality as argued by Rawls or Rorty. Although it recognizes the specificity of the morality of public actions, it holds that this distinction (a historical product of the liberal tradition) fails to show other aspects of their relation can support moral pluralism, that the provide the limit to public actions, and, finally, that personal convictions can play a stabilizing role in political life.KEYWORDSMORAL PLURALISM-PUBLIC MORALITY-PRIVATE MORALITY
Modernidad, dialéctica y filosofía en el pensamiento de T. W. Adorno
Authors: Esteban Enguita José E.
Published: April 2020

RESUMENLa finalidd del artículo es exponer algunos aspectos de la filosofía dialéctica de Adorno. Esta exposición se centra en dos puntos: 1) La relación sujeto-objeto desde una concepción negativa y materialista de la dialéctica; y 2) La crítica que esta concepción de la dialéctica hace a la modernidad filosófica y, en último término, a la totalidad de la filosofía occidental.PALABRAS CLAVEADORNO-MODERNIDAD-DIALÉCTICAABSTRACTThe main aim of this article is to expose some aspects of Adorno´s dialectycal philosophy. This exposition gets centred on two issue: 1) Subject-object relationship from a negativist a materialistic dialectical position; and 2) The criticque made, from this dialectical conception, to philosophycal modernity and, finally, to Western philophy as a whole.KEYWORDSADORNO-MODERNITY-DIALECTICS
El conexionismo: un nexo entre las neurociencias y las ciencias cognitivas
Authors: Caño A. , Luque J. L.
Published: April 2020

RESUMENSe presenta el conexionismo como un marco común para la comunicación entre neurociencias y ciencias cognitivas. En primer lugar, se exponen los rasgos básicos de la nueva metáfora del cerebro y cómo diferentes componentes de la cognición, tales como la representación, la memoria y el aprendizaje, son considerados desde la perspectiva conexionista. En segundo lugar, se discute la delimitación del nivel de estudio y de explicación propio de estos modelos. En este contexto, se distinguen dos estrategias: la modelización inspirada y la restringida neuronalmente, revisándose ambas a la luz de la clásica división de los niveles de explicación para las neurociencias propuesta por Marr. Por último, se presenta la potenciación a largo plazo (PLP) como un mecanismo de plasticidad sináptica especialmente interesante, ya que la PLP parece adaptarse a los requisitos de la regla de Hebb, que ha sido implementado con éxito en diferentes modelos conexionistas.ABSTRACTConnectionism as a common framework to neurosciences and cognitive sciences is presented. Firsty, major characteristics of the new brain metaphor are exposed an several cognition components, such as learning, memory and representation, are considered within the connectionist view. Secondly, the boundaries of the study and explanation level for these models are discussed. In this context, two strategies are considered within the explanation levels for neurosciences proposed by Marr. Latsy, long term potentation (LTP) is introduced as a specially interesting mechanism for synaptic plasticity because LTP satisfies the Hebbian rule requirements, which has been succesfully implemented in different connexionist models.
El regreso de la diosa Fortuna en la «sociedad del riesgo»
Authors: González García José M.
Published: April 2020

ResumenEl artículo presenta una de las versiones de la teoría sociológica del riesgo, en la tradición de estudios sobre la diosa Fortuna. En concreto, la desarrollada por Ulrich Beck. Desde esta posición, analiza la interpretación que beck hace de la modernidad en los términos de «modernidad reflexiva» y extrae las consecuencias que se derivan para una concepción moderna y reflexiva de lo políticoPALABRAS CLAVEMODERNIDAD-POLITICA-RIESGO-BECK-FORTUNAABSTRACTThe paper deals with one of the versions of the sociological theory of risk, within the tradition of studies on the goddess Fortune. Namely, the one developed by Ulrich Beck. From this position, it examines Beck's interpretation of modernity in terms of «reflexive modernity» and draw its consequences for a modern, reflexive conception of the political KEYWORDSMODERNITY- POLITICS-RISK-BECK-FORTUNE
Exploración biomecánica de la carrera en futbolistas de profesionales colombianos: propuesta inicial
Authors: Echavarria-Calderon M , Galvis-Rincon JC
Published: April 2020

Introducción: El fútbol es el deporte en equipo más popular alrededor del mundo, se estima que alrededor del 4% de la población mundial lo practica (1), su actividad involucra correr, patear, saltar, parar y realizar cambios de dirección en altas y medias velocidades. La biomecánica de la carrera es importante ya que permite mejorar la técnica, e impactar en la prevención de lesiones.Objetivo: determinar las características biomecánicas de la carrera de los jugadores de un equipo de fútbol profesional.Métodos: estudio observacional descriptivo tipo serie de casos de la carrera en 12 jugadores de fútbol profesional. Se incluyeron jugadores de 18 a 35 años pertenecientes al equipo sin lesiones de rodilla, cadera o tobillo en las últimas 4 semanas.Resultados: La mediana de la velocidad fue 7.44 m/s [RIQ: 6,93 – 7,75 m/s] siendo mayor en la pierna derecha 7.49 m/s [RIQ 6,88 – 7,74 m/s] que en la izquierda. La mediana de la longitud de zancada, fue 3,21 m (RIQ 3,05-3,64 m) con predominancia en la pierna derecha 3.20 m [RIQ 3,11-3,74 m]. Se evidenció que el jugador de la posición volante fue quien mayor velocidad presentó, mientras que el volante derecho fue quien presentó la menor velocidad del grupo evaluado.Conclusión: El estudio biomecánico de los futbolistas profesionales permite una caracterización del gesto deportivo de la carrera, permitiendo una visión diferente a las actualmente utilizadas tanto para la mejora en el rendimiento y estrategias de entrenamiento, como en la posible intervención en la prevención de lesiones.
Interfacial Acidity on Oxide Surfaces: A Scaling Paradigm and the Role of the Hydrogen Bond
Authors: Chapleski Robert , Chowdhury Azhad U. , Mason Kyle , Sacci Robert , Doughty Benjamin , Roy Sharani
Published: April 2020

A fundamental understanding of acidity at an interface, as mediated by structure and molecule-surface interactions, is essential to elucidate the mechanisms of a range of chemical transformations. While the strength­­­­ of an acid in the gas and solution phases is conceptually well understood, how acid-base chemistry works at an interface is notoriously more complicated. Using density functional theory and nonlinear vibrational spectroscopy, we have developed a method to determine the interfacial Brønsted-Lowry acidity of aliphatic alcohols adsorbed on the {100} surface of the model perovskite, strontium titanate. Here we show that, while shorter and less branched alkanols are less acidic as a gas and more acidic in solution, shorter alcohols are less acidic whereas less substituted alkanols are more acidic at the gas-surface interface. Hydrogen bonding plays a critical role in defining acidity, whereas structure-acidity relationships are dominated by van der Waals interactions between the alcohol and the surface.
LEONARDO DICAPRIO'S MOVEMENT AND COMBAT AGAINST CLIMATE CHANGE ON HIS U.N. SPEECH
Authors: Maharani Amanda Vira
Published: April 2020

Leonardo DiCaprio was chosen as United Nations Messenger of Peace in 2014 and gave speech in the Paris Agreement on the U.N. This research aim to find out how climate change described on the lexical choices used by Leonardo DiCaprio on his U.N. speech to convey his ideology. This research uses qualitative research design with critical discourse analysis approach proposed by Norman Fairclough. The data of this research is Leonardo DiCaprio’s speech at the opening of Signature Ceremony for the Paris Agreement by the U.N. The result is his ideology is represented on his lexical choices, which are positive and negative representation that describes his movement and combat against the climate change that represents on his U.N. speech as Messenger of Peace on climate change.
Methods of students work on vocal pieces in the class of solo singing
Authors: Gmyrina Svitlana
Published: April 2020

The article examines one of the aspects of the professional training of future singers and teachers of solo singing in the system of university education. The scientific-pedagogical,vocal, methodical and practical experience accumulated in this area has been analysed. It has been found out that students’ methods of work on vocal pieces require scientific basis. Those methods contribute to the effective formation of professional competencies. On the basis of this, the purpose of the research is formulated and the hypothesis that the preparation of students for concert performing and vocal pedagogical activities will be more effective if the work on vocal pieces rationally combines general scientific, didactic and special musical principles, methods and means of teaching, taking into account modern level of development of the vocal arts. The application of methods of analysis, pedagogical observation and generalization enabled us to obtain positive results of scientific research. The essence of the concepts of ‘teaching methods» and «means of teaching» in the high school and the specifics of their implementation in vocal training of students is revealed. The role of vocal pieces in the formation of professional competencies of students is described. The effective and pedagogically expedient methods of work on vocal pieces in the class of solo singing are determined. We concludes that: 1) work on vocal pieces in the class of solo singing is the most important component of of future vocalists training for their professional activity; 2) students’ mastering of scientifically grounded methods of work on vocal pieces contributes to the successful formation of vocal-performing, vocal-stage, vocal-methodical and other professional competencies; 3) success of students’ work on vocal pieces in the classroom of solo singing depends on the ability of teachers rationally combine general scientific, didactic and special musical principles, methods and means of teaching.
Influence of biological fertilizer and plant cover in the physical properties of soil
Authors: Ascari João Paulo , Araújo Dejânia Vieira de , Mendes Inês Roeder Nogueira , Prieto Rafael Sbruzzi , Carvalho Marco Antonio Camillo de
Published: April 2020

As propriedades físicas do solo exercem influencia no crescimento radicular das plantas, que dependendo do nível de restrição, a produtividade da cultura é reduzida. O objetivo deste estudo foi verificar os efeitos da adubação biológica e plantas de cobertura sobre as propriedades físicas do solo. O estudo foi desenvolvido em duas safras (2015/16 e 2016/17), onde o delineamento experimental foi em blocos casualizados em esquema fatorial duplo: adubo biológico (com e sem) e condições de cobertura vegetal do solo (milheto, crotalária e pousio limpo), e um fragmento de floresta como testemunha. A adubação biológica e as plantas de cobertura do solo promoveram incrementos significativos na umidade do solo, macroporosidade e porosidade total, além de reduzir a microporosidade e a resistência do solo a penetração. Deste modo, as propriedades físicas do solo foram incrementadas com o uso de adubo biológico, milheto e crotalária como cobertura do solo. O adubo biológico não promoveu incrementos de produtividade da soja e do milho, entretanto, estas apresentaram incrementos significativos com o uso de milheto e crotalária.
Nilai Total Flavonoid dalam Black garlic (Allium sativum L.) berdasarkan fraksi pelarut dan Aktivitas Antioksidannya
Authors: Wardhani Gladys Ayu Paramita Kusumah , Azizah Mia , Hastuti Lisnawati Tri
Published: April 2020

Black garlic adalah produk bawang putih yang telah diproses melalui reaksi pencoklatan non enzimatis (Reaksi Maillard) pada suhu tertentu dalam waktu lama, sehingga menghasilkan senyawa baru yang mempunyai efek farmakologis, salah satunya sebagai antioksidan. Flavonoid merupakan kelompok senyawa fenolik terbesar yang terdapat pada tanaman, diketahui dapat   menangkal   stres   oksidatif di tubuh manusia. Penelitian ini bertujuan untuk   menentukan kandungan  total flavonoid dari fraksi   black garlic   (Allium Sativum L.) serta menentukan aktivitas antioksidannya pada fraksi yang memiliki nilai total flavonoid tertinggi. Tahap  pertama  adalah  perolehan  total ekstrak  metanol,  selanjutnya ekstraksi fraksinasi  menggunakan air, diklorometana dan n-heksana.  Tahap  kedua adalah  uji  kualitatif  senyawa  flavonoid dengan metode Wilstatter.  Tahap  ketiga  adalah  analisis  total  flavonoid dengan metode standar eksternal menggunakan instrumen Spektrofotometer UV-Vis. Tahap terakhir adalah uji aktivitas antioksidan dengan standar Kuersetin. Hasil yang diperoleh yaitu ekstrak black garlic dalam air, diklorometana, dan  n-heksana positif mengandung flavonoid. Ekstrak diklorometana memiliki nilai total flavonoid paling besar yaitu 55,68 mg QE/g ekstrak, diikuti oleh nilai total flavonoid ekstrak air dan ekstrak n-heksana masing-masing sebesar 10,31 dan 5,11 mg QE/g ekstrak. Nilai IC50 black garlic dalam ekstrak diklorometana sebesar 361,07 µg/mL sehingga digolongkan sebagai senyawa dengan tingkat antioksidan yang sedang. Kata Kunci: black garlic, flavonoid, antioksidan, diklorometana
Analisis Kelayakan Usaha Produksi Tahu Sumedang (Studi Kasus Di Pabrik Tahu XY Kecamatan Conggeang)
Authors: Sa'id Nur Ali , Ma'ruf Amar , Delfitriani Delfitriani
Published: April 2020

Feasibility analysis of XY tofu production business is a factory that produces traditional food typical of the Sumedang district. This production utilizes the marketing sector and marketing location which is located near the sub-district traditional market. This study aims to analyze the business of tofu Sumedang in the XY tofu factory which includes non-financial aspects (Market aspects, marketing, engineering, management, legal, social and environmental), and financial aspects. Based on non-financial results hat the non-financial aspects affect the operation of the tofu XY production business.  Based on the results of the calculation of financial aspects it is feasible to carry out the NVP value generated for 10 years Rp. 579,177,261 -, with production capacity per month producing tofu 216.000 seed and 6.806 kg tofu dregs per month. The IRR  obtained is 0,41% where the IRR is more than 0%. Net B / C obtained is 2,92, this means, every Rp. 1 spent on running this business will generate net benefits of Rp.2,92. The payback period obtained is 2,63 years. The sensitivity analysis for this project shown an increase in operational / production costs of 10%, an increase in raw materials and additional materials by 20% and a decrease in selling prices by 10% which does not affect this business.Keywords: feasibility business, financial analysis, sensitivity analysis
Applying the TOPSIS Approach for Selecting the Best Small Project
Authors: Al-Zubaidy Sawsan Sabeeh , Al-Bayati Esraa Ibrahiem
Published: April 2020

Abstract: Projects selection is a significant problem. However, regularly challenging task. It is difficult because there is typically more than one measurement of the effects on all projects, particularly when there are multiple decision-makers. In this paper, the authors consider a tangible presentation of projects choosing for a different number of projects through an experts opinions by a group decision-making method called TZOPSEIS (Technique for Order Preference by Similarity to an Ideal Solution). This method is characterized by its ability to measure the relative performance for each alternative in a simple mathematical form. Four criteria have been deliberated to select the finest one among five projects and rank them. The proposed manner is used in a case study in the Iraqi environment which is analyzed from diverse directions of vision to evaluate and select the best small project.
Divergence & Probability Density : A Hypothesis
Authors: DATTA JAYDIP
Published: April 2020

The earlier work by Datta et al ( 1 ) the note has been made with the algebraic properties of Probability ie P (A) +P(B )= P ( A*B ) . This is termed as multiplicative rule of Probability. By multiplication rule any number say a can be first diverged through a series of a ( pow ) x , Where x is an integer like 0 to n . REF :PROBABILITY & WAVEFUNCTION : A NOTE November 2019 DOI: 10.31219/osf.io/awk96
Middle Test Strategi Pembelajaran Sejarah
Authors: Gymmayil Orm Aqil
Published: April 2020

Seorang guru sejarah yang baik sepantasnya mampu menyampaikan materi sesuai dengan perkembangan zaman. Disisi lain guru di harapkan mampu menguasai teknologi untuk mempermudah dalam proses belajar dan mengajar. Guru harus bisa menyiapkan strategi dalam pembelajarannya.
Jawaban Middle Test mata kuliah Strategi Pembelajaran Sejarah
Authors: Amin Mursidul
Published: April 2020

Tulisan ini dibuat sebagai jawaban middle test mata kuliah Strategi Pembelajaran Sejarah, Program Studi Pendidikan Sejarah FKIP Universitas Lambung Mangkurat Banjarmasin.
Jawaban Ulangan Tengah Semester dari mata kuliah Strategi Pembelajaran Sejarah
Authors: Ariyani Risma
Published: April 2020

Hasil analisis mengenai konsep berpikir kritis hingga membentuk historical empathy dari penalaran berpikir historis untuk mencapai tujuan pedagogi sejarah.
Audit Sistem Informasi Absensi pada PT. Bank Central Asia Tbk menggunakan COBIT 4.1
Authors: satria dedi
Published: April 2020

BCA adalah bank nasional yang didirikan pada tahun 1957 dan telahterus tumbuh. Saat ini bank telah mendukung bisnisproses di berbagai perusahaan, seperti penggunaan absensisistem Informasi. Selama implementasi sistem ini, ia telahtelah berjalan untuk mendukung prosedur kehadirankegiatan. Tujuan dari penelitian ini adalah untuk mendapatkan gambaran umum tentangkinerja tata kelola teknologi informasi di Indonesiauntuk menentukan tingkat tingkat kematangan yang saat ini sedang berjalan, dengan beberapa aspek untuk dipertimbangkan sepertiefektivitas dan efisiensi. Kesimpulan itu bisa ditarik dari penelitian yang telah dilakukan adalah tata kelola TI pada PT BCA telah dilakukan, meski masing-masing masih berjalan optimalProses TI yang terdapat di sub domain Monitor Evaluate Menilai (MEA) rata-rata berada pada 3,0 (proses yang ditentukan) untuk subdomain DS1, DS5, DS10 dan ME2.
Middle Test Lisa Margaretha Songan (1810111220010)
Authors: Songan Lisa Margaretha
Published: April 2020

Hasil analisis dokumen untuk pernyataan 1. Hasil analisis dokumen untuk pernyataan 2. Referensi
local conformal focusing and surface integral
Authors: Kuyukov Vitaly
Published: April 2020

local conformal focusing and surface integral
Islamic Education in Southeast Asia
Authors: Setiawan Adib Rifqi
Published: April 2020

Islamic Education in Southeast Asia reflects the diversity of Islam in that part of the world and of course plays a central role in shaping and transmitting the region’s religious traditions. this work concludes that Southeast Asia has an extraordinarily large and well-developed structure of Islamic education that can be a resource of critical importance in the ongoing war of ideas within Islam.
Блохи мелких млекопитающих юга Западно-Сибирской равнины в пределах северо-востока Казахстана
Authors: Ибраев Д.О. , Рустемханова С.С. , Габдуллин Е.С. , Мынбаева Б.Н. , Насифуллина Ж.Ж.
Published: April 2020

В статье приведены результаты исследования 2014–2018 гг. фауны блох мелких млекопитающих, сприведением перечня хозяев в степной природной зоне юга Западно-Сибирской равнины северо-востока Казахстана. Было обследовано 9 видов мышевидных грызунов, на которых выявлено 12 видов блох, являющихся представителями трех семейств: Leptopsyllidae, Hystrichopsyllidae и Ceratophyllidae. Массовым видом на животных является Peromyscopsylla bidentataKol., многочисленны Pectinoctenus pavlovskyiIoff. и Amalareus penicilliger Grube, остальные виды малочисленны. Наибольшим разнообразием отличилась популяция блох на Myodes rutilus Pall. и Lagurus lagurus Pall.
Study of spreading and plant resources of herbs Scabiosa ochroleucaL. and Scabiosa isetensisL. on the territory of Karaganda region
Authors: Ishmuratova М.Yu. , Zhunussova М.А. , Tyrzhanova S.S. , Silant’eva M.M.
Published: April 2020

The results of the study of the distribution and raw stocks of herbs Scabiosa ochroleucaand Scabiosa isetensisare presented in the article. Populations involving Scabiosa ochroleucaare timed to meadow, stable meadows, scaffolding forests, river valleys, and intersectional downhill. Individuals grow on the territory of the mountains of Karkaraly, Kuu, Ulytau, Ortau, Kyzyltau, Aksoran, Kent, Bektauata, Buyratau, Spasskiy hills, on river valleys of the rivers Nura, Sherubai-Nura, Sarysu, Shiderty, etc. Features of growth of Scabiosa ochroleucaas a part of a cereal-herbal variaScabiosa ochroleuca, scabiosa-herbal varia, herbal varia-cereal and herbal varia-shrubby community are described. Yield of above-ground was 220–350 kg/ha (in terms of air-dry weight). The total area of detected crops with the participation of Scabiosa ochroleucaco-set 61.3 hectares with an exploitation reserve of 186.26 centners, the volume of possible collection of raw mate-rials — 111.76 centners. The growth of Scabiosa isetensisis timed to the slopes and tops of rocky nozzles, slopes of mountains, steppe raenine areas. Individuals of this species are found in the mountains of Karkaraly, Ulytau, Ortau, Kyzyltau, in the desert of Beth-pakdala, on the exits of rocks of the Central Ka-zakhstan small breeder as part of scabiosa-stipa-herbal varia and cereal-herbal varia communities. Yield of air-dry raw materials was 285–310 kg/ha. The total area is calculated at 29.8 ha, exploitation reserve is 87.83 centners, the volume of possible raw material collection is calculated at 52.70 centners.
The study of some structural parameters of the flora of chink Dongyztau (Aktobe region)
Authors: Kuanbay Zh.I. , Abiyev S.А. , Tikhomirov V.N.
Published: April 2020

The results of the study of structural indices of the flora of vascular plants chink Dongyaztau are presented in the article. According to the classification of life forms of I.G Serebryakov, the dominant share is occupied by perennial polycarpic herbs — 124 species, or 39.5 %, on the second position there are monocarpic herbs — 123 species, or 39.1 %. Semi-wood species make up 43 species, or 13.7 %, wood forms — 21 species, or 6.7 %. A high proportion of ephemera was noted which are 28 species, or 8.9 %. According to the classifica-tion of C. Raunkiaer in the flora chink Dongyztau is dominated by therophytes — 119 species, or 37.9 %. On the second place there is a group of hemi-cryptophytes — 104 species, or 33.1 %; in third place — chameophytes (46 species, or 14.6 %); in the fourth position — cryptophytes (31 species, or 9.9 %); on the fifth — phanerophytes (14 species, or 4.5 %). The ratio of life forms of plants according to both classifications confirms the climatic conditions of the region — sharp-continental and arid climate, timed to the desert zone of Kazakhstan. There are 10 useful groups of plants: fodder — 110 species; technical — 30 species; medicinal — 48 species; melliferous — 13 species; ornamental — 33 species; food — 33 species; vitamin — 11 species; poi-sonous — 32 species; insecticidal — 8 species; soil-, forest- and phytomeliorative — 11 species.
Цитоморфологическая оценка эпителия щек у лиц, проживающих в условиях экологически неблагоприятного региона
Authors: Сабиров Ж.Б. , Намазбаева З.И. , Бакбергенов М.Б. , Жарылкасын Ж.Ж. , Мукашева М.А. , Картбаева Г.Т. , Русяев М.В. , Кушербаев С.А. , Жалмаханов М.Ш.
Published: April 2020

Изучены частота встречаемости патологических эпителиальных клеток слизистой оболочки рта у лиц, проживающих в условиях повышенной химической нагрузки, цитоморфологические показатели и показатели активности мутагенеза (микроядро, протрузии, сдвоенное ядро, многоядерные клетки эпителиоциты). Установлены цитоморфологические и цитогенетические нарушения в соматических клетках в виде увеличения числа эпителиоцитов с клеточной вакуольной дистрофией, обсемененностью микрофлорой, частотой многоядерных клеток. Отмечено, что назальные и буккальные эпителиоциты обладают чувствительностью к различным экзогенным и эндогенным воздействиям экофакторов, что сказывается на функциональных изменениях этих клеток, где наблюдаются различные нарушения местного значения.
Морфолого-анатомическое исследование Kochia prostratа и Kochia scoparia
Authors: Сакибай А.Д. , Байжигитова Б.А. , Тулеуов У.Б. , Драсар П.Б. , Темиргазиев Б.С. , Тулеуов Б.И. , Адекенов С.М.
Published: April 2020

В статье изложены результаты сравнительного морфолого-анатомического исследования надземныхорганов Kochia prostrata и Kochia scoparia. Сырье заготавливали на территории Карагандинской области, анализировали показатели внешнего вида, выполняли анатомические исследования поверхностных препаратов и срезов. Для обоих видов установлены диагностические признаки на микро- и макроскопическом уровнях. На макроскопическом уровне диагностическими признаками сырья являются особенности строения и формы побегов и листа, окраска, степень одревеснения побега и опушения листа, побега и околоцветника, наличие черешка, форма соцветия, количество цветков в соцветиях. Диагностическими признаками сырья кохии веничной и кохии простертой на микроскопическом уровне являются следующие: форма и строение клеток эпидермиса листа, наличие друз оксалата кальция, степень и выраженность опушения на эпидермисе листа, строение листа и стебля на поперечном срезе. Полученные результаты войдут в нормативные документы на траву кохии простертой и кохии веничной.
Preposições: construção de uma abordagem variacionista no ensino médio
Authors: Thomé Viegas Elaine Marques
Published: April 2020

Este artigo trata de uma nova abordagem das Preposições na Educação Básica, em especial, no Ensino Médio. Para tal, recomenda-se a discussão, em sala de aula, sobre heterogeneidade do sistema linguístico, variação linguística e teoria Sociolinguística. Em seguida, apresenta-se um estudo variacionista sobre a possibilidade de alternância das preposições. O artigo prossegue com a proposta de construção da abordagem desse componente gramatical para alunos do Ensino Médio. Na conclusão, retoma-se a importância tanto da pesquisa linguística para o ensino de Língua Portuguesa, quanto de uma metodologia de ensino adequada para evitar o preconceito em relação às variedades linguísticas não adquiridas na escola.