bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficiency of surgical treatment of neovascular glaucoma: a retrospective analysis
Authors: Zolotarev A. V. , Karlova E. V. , Radaikina M. V. , Kuz'mina A. A. , Ryzhkova O. V.
Published: July 2023

Purpose: to compare the results of neovascular glaucoma (NVG) surgery of patients treated for the underlying eye disease with antiVEGF therapy and laser coagulation (LC) of the retina with the surgery results of patients who did not receive underlying disease treatment.

Materials and methods. A retrospective analysis of case histories and outpatient charts of 70 patients (70 eyes) with NVG, operated in a surgical hospital, involved two groups of patients: group 1 — 33 eyes of patients treated for the underlying disease with anti-VEGF therapy and/or LC; of these, 13 eyes (39 %) received panretinal LC, 15 eyes (45 %) received an anti-VEGF drug intravitreally, and 5 eyes (16 %) received both anti-VEGF therapy and LC); group 2 — 37 eyes of patients not treated for the underlying disease. In group 1, NVG was caused by diabetic retinopathy (DR), which accounted for 19 eyes (57.6 %), and post-thrombotic retinopathy (PR) — 14 eyes (42.3 %). IOP data in group 1 at admission was 38.00 ± 6.82 mm Hg. In group 2, the proportion of patients with DR was 32 % (12 eyes), and those with PR — 41 % (15 eyes). The level of IOP in group 1 upon hospital admission was 38.00 ± 6.82 mm Hg, while in group 2 it was 35.97 ± 5.85 mm Hg.

Results. In group 1, in most cases, the classical surgical approach to NVG treatment was used. The proportion of Ahmed drainage implantations was 46 % (15 eyes), trabeculectomy (TET) — 24 % (8 eyes), non-penetrating sinustrabeculectomy (NST) — 6 % (2 eyes), and only 24 % (8 eyes) received transscleral cyclophotocoagulation (CPC). After 7 days, the average level of IOP in group 1 was 16.80 ± 7.18 mm Hg, after 1 month, 19.50 ± 3.45 mm Hg, after 3 months, 21.80 ± 3.15 mm Hg, and after 6 months — 22.57 ± 3.34 mm Hg (p < 0.05). In group 2, the operation of choice was CFC, which was performed in 46 % (17 eyes), the Ahmed drainage was implanted less often — 36 % (13 eyes), while 18 % (7 eyes) accounted for TET. The IOP level in group 2 after 7 days was 20.00 ± 8.74 mm Hg, after 1 month, 25.30 ± 4.67 mm Hg, after 3 months 28.43 ± 6.54 mm Hg, and after 6 months 29.73 ± 4.18 mm Hg (p < 0.05).

Conclusion. The timely treatment of the underlying disease with Anti-VEGF and LC of the retina allows the patient to maintain visual functions, and increases the effectiveness of NVG surgery.
Complicated COVID-19 conjunctivitis. A case report
Authors: Babushkin A. E. , Matyukhina E. N. , Saitova G. R. , Israfilova G. Z.
Published: July 2023

A clinical case of viral conjunctivitis COVID-19, which was complicated by partial symblepharon and severe dry eye syndrome, is presented. The latter was treated for several days with eye drops containing solutions of glucocorticosteroid, a cytostatic and an antiseptic combined with tear replacement therapy, which however led to an extensive detachment of the corneal epithelium of the right eye, a superficial ulcer and an area of keratomalacia in the lower part of the cornea. In view of this, a further hospital treatment was required: the patient received anti-inflammatory and keratoprotective drugs. A subsequent medical consultation found out that the patient had periodically instilled oxybuprocaine hydrochloride 0.4% into the right eye for pain relief for a long time (4 months) without informing the attending physician. As a result of hospital treatment, the condition of the patient’s right eye improved: the corneal ulcer, was epithelialized, followed by the formation of a vascularized corneal leukoma. In our opinion, a deterioration of the tear film stability of the patient, who had had COVID-19 accompanied by ocular manifestations in the form of initially developed conjunctivitis, was due to the anesthetic effect of long-term instillations of oxybuprocaine hydrochloride. This led to a significant decrease in tear secretion, a decrease in the density of goblet cells of the conjunctiva and a violation of the sensory innervation of the cornea, which gradually brought about a severe dry eye syndrome. The above case clearly demonstrates the importance of increasing the patients’ awareness of the harm that could be caused by long-term use of local anesthetics without a doctor’s approval.
Congenital ocular manifestations in children born to mothers who had COVID-19 coronavirus infection during pregnancy. Clinical cases
Authors: Pleskova A. V. , Mamakaeva I. R. , Katargina L. A. , Panova A. Yu. , Lugovkina K. V.
Published: July 2023

Preliminary data show that the incidence of eye damage in COVID-19 reaches 32%, with a diverse range of clinical manifestations. Both the anterior segment of the eye (conjunctivitis, keratoconjunctivitis) and the posterior segment (retinal vascular thrombosis, neuritis, neuroretinitis) can be affected. The infection in children is diagnosed much less frequently than in adults, so ophthalmic manifestations have hardly ever been studied.

Purpose: to present cases of congenital eye lesions in children born to mothers who had COVID-19 during pregnancy.

Material. We present 4 clinical cases of ocular manifestations in newborns born to such mothers.

Results. 4 variants of congenital ocular manifestations are reported. Clinical manifestations are listed, and treatment tactics for such patients is proposed.

Conclusion. In order to timely diagnose, and choose the optimal treatment tactics of such conditions, thorough collection of case history and the ophthalmologists’ awareness of ocular symptoms of COVID-19 manifestations is essential.
Visual and neurological complications of COVID-19
Authors: Ioileva E. E. , Safonenko A. Yu. , Golubeva O. V. , Bolbachan K. N.
Published: July 2023

The review summarizes the evidence of visual and neurological complications in the acute stage of COVID-19 and in post-COVID syndrome. Neurological symptom complexes, and cerebrovascular disorders are described. Ophthalmologic manifestations may be a typical sign of COVID-19 onset, but they may also develop several weeks after recovery. The spectrum of neuro-ophthalmological manifestations in most cases includes optic neuritis, optic disc edema, optic neuropathy, and venous thrombosis. Ophthalmologists should be aware of the possible associations of ocular diseases with COVID-19 in order to diagnose and initiate an early treatment for life and vision threatening complications.
Simultaneous Determination of Glyphosate, AMPA and Inorganic Anions in Water Samples by Gradient Capillary Ion Chromatography
Authors: de Matos Fábio , de Carvalho Gabriel , Prestes Osmar , Adaime Martha , Zanella Renato
Published: July 2023

The herbicide glyphosate is the most widely used pesticide worldwide. Glyphosate and its major metabolite, aminomethylphosphonic acid (AMPA), have been frequently found in water samples. The widely used methods for determining these compounds are expensive and environmentally unfriendly due to reagent consumption for derivatization. Another possibility is the use of classic ion chromatography, albeit with low sensitivity and subject to interferences. Therefore, this study aimed to develop a method to directly and simultaneously determine glyphosate, AMPA, and common inorganic anions in water samples using gradient capillary ion chromatography without sample pre-treatment and derivatization. The proposed method was validated, presenting adequate linearity for glyphosate and AMPA with a determination coefficient (r2 ) > 0.998. Recoveries ranged from 94 to 105% and 79 to 113% for glyphosate and AMPA, respectively, with a relative standard deviation < 10%. The practical method limits of detection and quantification for both glyphosate and AMPA were 7.5 and 25 µg L-1, respectively. The method presented satisfactory results for the anions fluoride, chloride, bromide, nitrite, nitrate, phosphate, and sulfate, with limits of detection ranging from 7.5 to 200 µg L-1. Application of the method in water samples proved simple, efficient, and cost-effective, enabling the monitoring of these analytes in different water matrices.
A Global Multi-sector Multi-region Foreign Direct Investment Database for GTAP
Authors: Lakatos Csilla , Walmsley Terrie
Published: July 2023

A global bilateral multi-region multi-sector foreign direct investment (FDI) stocks and flows database has been contributed to GTAP by Houssein Boumellassa, Christophe Gouel and David Laborde from CEPII (Centre d'Etudes Prospectives et d'Informations Internationales) as a result of a project initiated by DG Trade of the European Commission. Contrary to other data sources on FDI this database is fully consistent, balanced and suitable for use in CGE work. The construction of this database is entirely documented in Boumellassa, Gouel and Laborde (2007). This document describes the steps used to convert this database into GTAP v7 sectoral and regional aggregation format. Accordingly, the final FDI stocks and flows database is bilateral with 113 regions and 57 sectors and base year 2004.
Development of the GTAP 7 Land Use Data Base
Authors: Avetisyan Misak , Baldos Uris Lantz , Hertel Thomas
Published: July 2023

The land-use augmented version of the GTAP Data Base has been used for a wide variety of applications (T. W. Hertel, Rose, & Tol, 2009). It builds on global land cover and land use data bases documented in Monfreda et al. (2008) and Ramankutty and Foley (1999) as well as global forestry data developed by Sohngen and Tennity (2004). The methodology for integrating this information into the GTAP-AEZ framework is documented by Lee et al. (2009). The underlying land use data were developed with a base year circa 2001 (The sub-national land use data varied in availability and spanned the period 1997-2003). The original GTAP-AEZ data base incorporated this information into the version 6 GTAP Data Base, with a benchmark year of 2001. Subsequently the GTAP Data Base (version 7) has been updated to 2004, and the version 8 data base will be released in 2011 with a base year of 2007. This memorandum documents how the land use data has been updated from 2001 to 2004 for use in the version 7 data base, by time series data on land cover developed by Navin Ramankutty and national production and harvested area data from the FAO. If a new version of the Monfreda et al. data base does not become available by 2011, this same approach could be used to update the land use data to the 2007 benchmark used in GTAP v.8.
Development of a GTAP 8 Land Use and Land Cover Data Base for Years 2004 and 2007
Authors: Baldos Uris Lantz , Hertel Thomas
Published: July 2023

The land-use augmented version of the GTAP Data Base has been used for a wide variety of applications (Hertel, Rose, & Tol, 2009). The original GTAP-AEZ database incorporated geospatial data on land use into the version 6 GTAP Data Base, with a benchmark year of 2001. The methodology for integrating this information into the GTAP-AEZ framework is documented by Lee et al. (2009). This database has been updated for 2004 using the version 7 GTAP Data Base, national-level crop production data from FAOSTAT and updated time-series data on cropland and pasture cover developed by Navin Ramankutty (2011). For version 7, the original geospatial data on crop production circa 2000 from Monfreda et al. (2008) was used since updates for this data are currently unavailable. This memorandum documents how the land use data has been updated for use in the version 8 data base. In keeping with the multi-year release of v.8, the Land Use Data Base is updated to two base years: 2004 and 2007. This update heavily relies on the methods outlined by Avetisyan, Baldos and Hertel (2010), but there are some changes in sources and procedures, as will become evident in the comparisons of the v.7-2004 and v.8-2004 data bases.
A Global Database of Foreign Affiliate Sales
Authors: Fukui Tani , Lakatos Csilla
Published: July 2023

There is a severe lack of data describing foreign affiliate activity. To fill this gap, we produce a new dataset to further the literature on the behavior of multinational firms. Eurostat’s Foreign Affiliate Statistics database, with a large number of sector-level, bilateral observations on foreign affiliate sales, provides a basis from which to extrapolate the relationship between various host and source country factors and the foreign affiliate activity produced by them. This paper exploits the detailed level of the data by introducing sector-specific variables that in turn permit out of sample predictions. Further, the large number of excess zeros in the Eurostat dataset presents added complexity and is addressed using techniques borrowed from the trade literature, which also experiences a "zeros" problem. The dataset produced in this paper also serves as an input into the GTAP-based FDI model of Lakatos and Fukui (2012). This model integrates the foreign affiliate sales dataset produced in this paper into a framework that permits the analysis of the behavior of foreign affiliates within the context of a general equilibrium model.
Polyartistic Approach in Music Education: A Tool for Teaching and Developing Creative and Critical Thinking
Authors:   Izmail State University of Humanities, Odesa, Ukraine, Yaoquan Jin , Ruiping Huang ,   Izmail State University of Humanities, Odesa, Ukraine, Yang Zhang ,   Izmail State University of Humanities, Odesa, Ukraine, Marchenko Valerii ,   V.I. Vernadsky Taurida  National University, Ukraine
Published: July 2023

The article presents two models for introducing a polyartistic approach in Bachelor’s and Master’s training. The study emphasizes the need to integrate art and art education into the educational process as a factor in the development of creative and critical thinking, communicative and sociocultural competencies of future music teachers. The first model, known as the linear one, implies the inclusion of polyartistic disciplines and tracks in the educational program. This model allows students to choose electives that meet their interests and professional qualifications. This approach provides students with flexibility in planning their academic path and learning issues related to polyartistic education more comprehensively. The second model, the concentric one, is used in the Master’s degree programs. This model enables students to expand their knowledge and skills in the polyartistic component based on the knowledge gained during their Bachelor studies. Students study polyartistic subjects and thus expand their theoretical, methodological, and performing skills. These two models can be used for training secondary school music teachers and teachers of institutions of supplementary art education. The introduction of a polyartistic approach into the discussed models helps to better understand and apply art as a tool for teaching and contributes to the development of creative and critical thinking, communicative and sociocultural competencies of future music teachers. This article suggests new approaches to the formation of the professional identity of music teachers, the development of students’ creative abilities, and the use of modern technologies in polyartistic education. The conclusions of this article can serve as a basis for further research and development of practical aspects of introducing a polyartistic approach into the process of training music teachers.
Ballet in Virtual Reality: On the Problem of Synthesizing “End-to-End” Technologies and Theatrical Stage Art
Authors:   The Kosygin State University of Russia, Moscow, Russian Federation, Portnova Tatiana V.
Published: July 2023

The article is devoted to the study of the problem of synthesizing “end-to-end” technologies and theatrical (stage) art. The author proceeds from the fact that in the era of industrialization, a person’s perceptual practices are carried out through the prism of a new, generative reality, which, consequently, causes the transformation of the spatial-temporal model of aesthetic experience. However, the artist as the creator of a work of art, having a special sensitivity to reality, can see what may be inaccessible to his audience. The hypothesis is put forward that this ability is based on a simultaneous perception of time and space, the fundamentalization of which in the perceptual practice and aesthetic experience of the viewer is the main task of a modern artist. The verification of this hypothesis was carried out through the prism of the synthesis of virtual reality as an “end-to-end” digital technology and stage (choreographic) art, where time and space become the subject of artistic reflection. The methodological foundation of the research is based on a discursive analysis, which allows us to understand, firstly, how modern stage (choreographic) digital art offers the viewer to make a path on his own, with a “previously passed meaning” and with the help of his already existing perceptual experience; secondly, how the artist, as the creator of a work of digital art, builds and carries out a “conversation” with the viewer through the prism of the simultaneous communicative space initiated by him. The author emphasizes that a modern artist, regardless of his/her role in art, must have the skill of discursive analysis to be able to create a communicative space in which the viewer will be able to gain perceptual experience and independently “realize” the temporal-spatial mega-code, and understand the idea of the artist, regardless of how much it is hidden from the audience. In turn, the ability to discursive analysis of the viewer will allow you to collect and disperse meanings, transform them, return them to their original state and let them go back into the element of the game of signifiers, offering yourself to overcome the path in the semantic landscape of the work of theatrical (stage, choreographic) art.
Environmentally sustainable zinc oxide nanoparticles for improved hazardous textile dye removal from water bodies
Authors: Gangwar Jaya , Pratap Singh Akshay , Marimuthu Nidhin , Kadanthottu Sebastian Joseph
Published: July 2023

A sustainable, affordable, and cost-effective method was developed to synthesize zinc oxide nanoparticles (SB-ZnO-NPs) using leaf extracts of Strobilanthes barbatus. The synthesized SB-ZnO-NPs displayed an absorbance maximum at 359 nm with a band gap of 3.24 eV. The average diameter of the SB-ZnO-NPs, as determined by FESEM analysis, was 84.23 nm. The particles had nearly spherical morphologies. By using FTIR analysis, it was established that functional groups played a part in the formation of SB-ZnO-NPs. Reactive Yellow 86 (RY-86) and Reactive Yellow 145 (RY-145) textile dyes were degraded by SB-ZnO-NPs under the impact of UV irradiation, and the degradation rates were 87.50 and 91.11%, respectively, in 320 min. When dye solutions treated with SB-ZnO-NPs were tested for phytotoxicity, the results showed a sharp decline in the effectiveness of the inhibition compared to dye effluents. The synthesised SB-ZnO-NPs can, therefore, be employed as a substitute potential catalyst for the breakdown of textile colours both before and after release into water bodies.
DIOS COMO “FUTURO ABSOLUTO” EN KARL RAHNER
Authors: Vigueras Alex
Published: July 2023

Este artículo tiene como objetivo presentar el concepto “Dios: Futuro absoluto” en el contexto del diálogo de Karl Rahner con la modernidad, más específicamente, con el evolucionismo, el marxismo y el futuro tecnológico. Es solo a partir del futuro absolu-to que se torna posible una historia humana, pues la libertad tiene como fundamento la incondicionalidad. Este futuro absoluto ya es interior al mundo a partir de la auto-comunicación de Dios, y desde ella es posible entender la evolución como un proceso de autotrascendencia activa. El punto de partida de la reflexión de Rahner es la libertad y la dignidad del ser humano individual, es decir, toma como punto de partida uno de los ejes fundamentales de la propia modernidad.
PANORAMA ÉTICO DE LA ENCÍCLICA CARITAS IN VERITATE
Authors: Flecha Andrés José-Román
Published: July 2023

La encíclica Caritas in veritate del Santo Padre Benedicto XVI es ya considerada como un interesante documento en la larga tradición de la enseñanza social de la Iglesia Católica. En el presente estudio se analizan algunos puntos más importantes de la tercera carta papal, con la intención de examinar su importancia para la ética social.
Microwave-assisted Synthesis, Molecular Docking Study of Spirofused
Heterocycles as Anti-microbial and Anthelmintic Potential
Authors: Das Rina , Mehta Dinesh Kumar , Gupta Sumeet , Mujwar Somdutt , Sharma Vishal , Goyal Anju , Patel Samir , Patel Archita
Published: July 2023

Introduction:

The stereochemical characteristics of spirofused and their derivatives have
recently attracted a great deal of interest in synthetic organic chemistry.

Methods:

A series of ecologically acceptable spirofused heterocycle compounds S(K1–K8) were
made using a one- pot microwave irradiation and were characterized by FTIR, 1HNMR, and Mass
Spectroscopy. The Iodine-catalyzed Biginelli-type condensation process has been used to synthesize
novel anti-microbial and anthelmintic potential spiroketals (spirofused) derivatives by using a fast,
safe & effective microwave irradiation approach in order to get the product in maximum yield with
lesser time consumption.

Results:

The compounds SK4 and SK5 showed promising antimicrobial activity against all bacterial
(Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli) and fungal
strains (Candida albicans and Aspergillus niger) with MIC 6.25 μg/mL and 12.5 μg/mL. Furthermore,
molecular docking studies were also simulated for compounds SK4 and SK5 to predict the specific
binding mode of these compounds.

Conclusion:

Albendazole (Alb) was used as a reference medicine to test the anthelmintic activity of
Indian adult earthworms Eisenia fetida. Compound SK4 has been found to be an effective
pharmacophore.
A Comprehensive Investigation into the Relationship between Dietary Therapy Strategies for Metabolic Illnesses and the Underlying Myriad Factors
Authors: Kusmy Prabin , Saxena Pal Rashmi , Chaitanya Motamari Venkata Naga Lalitha , Pal Yogendra
Published: July 2023

Maintaining a well-balanced diet and considering how to fulfill all the adequate nutrition required by the body will help us live a healthy lifestyle. The risk of illness, infection, exhaustion, and poor performance increases when a balanced diet is absent. The anti-treatment technique of food modification has gained a lot of attention in research over the past few decades. Popular diets include Mediterranean, vegan, and low-carbohydrate diets. The vegan diet is a plant-based eating plan that eliminates animal products and emphasizes fruits, vegetables, legumes, whole grains, nuts, and seeds. The Palaeolithic age diet emphasizes eating full, unprocessed foods available to early people while avoiding grains, legumes, dairy products, refined sugar, and processed foods. Proponents claim it can improve health, and aid in weight loss. Numerous dietary patterns, such as caloric restriction (CR), dietary approaches to stop hypertension (DASH), ketogenic diets (KD), the Mediterranean diet (Medi), and Mediterranean-DASH diet Intervention for Neurological Delay (MIND) diet, have been tried to reduce body weight, any other disease infections, and cognitive decline. Increased Mediterranean diet adherence was linked to reductions in cardiovascular and neurological conditions, including Alzheimer's disease (AD) and related cognitive loss. The MIND diet, a new good dietary pattern has been linked to a significantly lower incidence of AD and slower rates of cognitive deterioration. The current piece of work emphasizes the introduction, nutritional components, and health advantages of different types of diet.
Application of Nanotechnology in Wastewater Cleaning Process
Authors: Singh Monika , Pandey Deepanjali , Singh Dharamveer , Verma Shalini , Krishna Vijay
Published: July 2023

With the advancement in research, new techniques are growing very fast these days. The environmental contamination by many hazardous elements is seen in today’s world. The radioactive materials and their byproducts or the leakage of nuclear reactors is a potential serious health threat. The ground water and drinking water get contaminated and it is a big challenge to remove these radioactive ions from the environment. The radioactive ions leach into groundwater and contaminate drinking water supplies for large population areas. The key issue in developing technologies for the removal of radioactive ions from the environment mainly from wastewater and their subsequent safe disposal is to devise materials which are able to absorb radioactive ions irreversibly, selectively, efficiently, and in large quantities from contaminated water. Hence, nanotechnology proved to be a great success in this area. Nanotechnology is the science and technology working at the molecular level i.e. in nanometre and embraces many different fields and specialties, including engineering, chemistry, electronics, medicine, pharmaceuticals, agriculture and waste management. The present chapter deals with the development of nano-technology for the removal and safe disposal of radioactive ions from the environment using nanomaterials.
Eco-friendly Nature of Ionic Liquids
Authors: Himani Bentham Science Publisher , Raman Anirudh Pratap Singh , Jain Pallavi , Chandra Ramesh , Kumari Kamlesh , Kumar Vinod , Singh Prashant
Published: July 2023

Ionic Liquids (ILs) are believed to be designer solvents, and their use has helped to speed up research in the field of chemistry properties like high viscosity and low vapor pressure. ILs are well-known for their physicochemical properties that can be modified to obtain desired functionality and improved efficiency, analyte extraction selectivity, and sensitivity. ILs have been studied through the methodologies for their synthesis, recyclability after use, reusability for different applications, toxicity against living organisms, and degradation with time. Usually, ILs have considerably better solvents than traditional solvents, but their synthesis involves harmful chemicals. ILs have also proved to be superior lubricants to other lubricants, which show high performance because friction in ILs may be regulated actively by using an external electric potential even when it is diluted in oil. ILs are proven appreciable electrolytes and have significant performance in the generation of energy. ILs are considered an alternative to the traditional solvents obtained from fossils. This chapter will concentrate on current advances in surface and interfacial applications.
Interactions of Ionic Liquids With Metal Surface: Effect of Cations And Anions
Authors: Dagdag Omar , Haldhar Rajesh , Kim Seong-Cheol , Berdimurodov Elyor , Verma Chandrabhan , Akpan Ekemini D. , Ebenso Eno E.
Published: July 2023

The motivation behind recreating this chapter is to give a summary of the bibliographical insights expected to make the segment. In the first part, we examine the adsorption of ionic liquids (ILs) as efficient, effective and eco-friendly corrosion inhibitors for various alloys and metals surface in different corrosive media environments and the restraint and coordination chemistry of ionic liquids. The anticorrosive activity of different ILs has been examined with electrochemical techniques followed by weight-loss measurement. The impact of the ILs composition (polar and nonpolar substituents in anions & cations, and alkyl tail length), temperature, concentration, and nature of the medium, which influence the metal corrosion protection, was discussed. In the second part, we examine the interfacial structure and adsorption mechanism of different ILs on the Au (111) surface investigated via quantum chemical calculations.
Ionic Liquids in Decontamination of Toxic Metals Impurities
Authors: Sheetal Bentham Science Publisher , Kumari Anita , Singh Manjeet , Thakur Sanjeeve , Pani Balaram , Singh Ashish Kumar
Published: July 2023

The wide use of noxious and non-degradable metals due to industrialization has become a major factor in rising health concerns. Diseases associated may involve cardiovascular disorders, brain damage, cancer, etc., and this leads to the development of certain methods for the sole purpose of cleaning water, soil, air, etc., to remove metals categorized as toxic ones. Ionic liquids with remarkable thermal stability, association ability, exhibiting low vapour emission, etc., are considered eco-friendly for the decontamination of toxic metal impurities. These ionic liquids involve certain modes of interactions like an electrostatic, dipole, van der Waals, etc., for the effective separation and extraction of metals. Also, the property of reusability associated with ionic liquids makes them be used on a wide scale.
Ionic Liquids for the Surface Modification of Polymers and Medical Devices
Authors: Sasi Renjith , Sreejith S. L. , Joseph Roy
Published: July 2023

Ionic liquids (ILs) attracted global attention owing to their superior functional properties, making them useful for many applications. Low volatility, wide liquidity range, better miscibility with organic and inorganic materials, better electrochemical stability, and negligible toxicity earn them a green solvent status. ILs are suitable alternatives to many volatile and flammable organic solvents that chokes our environment. The presence of asymmetric organic/inorganic ions gave them unique characteristics similar to biomolecules. They could interact with the cell membranes and penetrate the lipid bilayers to destroy bacterial cell membranes. They can selfassemble at the interfaces of polar and non-polar media. The nature of substrates, concentration, counter-ions, and polarity of the medium influence the extent and stability of the self-assembly. The self-assembled monolayers (SAMs) and multilayers of ILs impart intriguing properties to the surfaces. Surface modification with ILs is preferred over other methods considering their eco-friendly nature. The IL-mediated surface modification would help to improve the surface properties of polymers, metals, nanoparticles, ceramics, stones, medical devices, etc. The modified surfaces would have improved wettability, biocompatibility, and antimicrobial or antiviral properties. IL-modified surfaces could anchor enzymes to generate sustainable biocatalysts for a wide range of reactions. The inherent affinity of ILs towards gases like CO2 makes them suitable for generating gas-adsorbing surfaces. Assembled charge carriers in ILs are helpful in energy storage and electrochemical sensing applications. Poly(ionic liquids) (PILs) are also receiving much attention recently since they display synergistic properties of polymers and ILs to be employed in divergent fields. PILs are also suitable for the surface modification of different substrates. This chapter reviews the surface modification of materials using ILs and PILs and their biomedical applications.
O projeto do século XVIII do Palácio Real da Ajuda dois desenhos de arquitetura
Authors: Pinto Ana Sofia , Rocha Marta
Published: July 2023

The Royal Palace of Ajuda, one of the main Portuguese royal residences during the 19th century, has a complex and long construction history, only recently completed, in 2021.Little is known about the palace’s original 18th century project, designed by the Portuguese baroque architect Manuel Caetano de Sousa. However, the contact in 2022, in a Portuguese archive, with two elevations of the Royal Palace of Ajuda depicting a language far removed from the neoclassical that would mark the work of the palace after 1802, plants the possibility of being faced with two of the missing drawings of Manuel Caetano de Sousa, made in the last years of the 18th century, a hypothesis that one will try to prove.
ÇOCUKLUK DÖNEMİ KORUYUCU YAŞANTILAR ÖLÇEĞİ (ÇD-KYÖ): ÇOCUK İSTİSMARI VE İHMALİNDE KORUYUCU FAKTÖRLERİN ÖLÇÜLMESİ*
Authors: Bayar Öznur , Doğan Türkan
Published: July 2023

Bu çalışmanın amacı retrospektif Çocukluk Dönemi Koruyucu Yaşantılar Ölçeği’nin (ÇD-KYÖ) geliştirilmesi ve ilk psikometrik özelliklerinin test edilmesidir. Bu amaçla dört çalışma grubuna ulaşılmıştır (n=894). Katılımcılar Türkiye’de klinik olmayan genç yetişkin üniversite öğrencileridir (Yaş aralığı=18-27). Ölçme araçları olarak ÇD-KYÖ, Çocukluk Çağı Travmaları Ölçeği (CTQ-33), Çocukluk Çağı Olumlu Yaşantılar Ölçeği (ÇÇOYÖ) ve Sosyo-Demografik Bilgi Formu kullanılmıştır. ÇD-KYÖ’nün geçerlik kanıtları için kapsam geçerliği, görünüş geçerliği, yapı geçerliği (açıklayıcı ve doğrulayıcı faktör analizi) ve ölçüt bağıntılı geçerlik kullanılmıştır. Güvenirlik için Cronbach Alfa, Mcdonald Omega ve Tabakalı alfa katsayıları hesaplanmıştır. Sonuçlar, üç faktörlü yapıdaki ÇD-KYÖ’den elde edilen verilerin yeterli düzeyde geçerli ve güvenilir olduğunu göstermiştir. Bu yapı doğrulayıcı faktör analiz ile incelenmiş ve model-veri uyumunun sağlandığı gözlenmiştir. ÇD-KYÖ ile ÇÇOYÖ arasında pozitif korelasyon bulunmuştur. ÇD-KYÖ ile CTQ-33 ve faktörleri arasında ise negatif yönlü korelasyonlar bulunmuştur. ÇD-KYÖ, çocuk istismarı ve ihmali sonrası olumlu çıktılarla ilişkili koruyucu faktörlerin araştırıldığı retrospektif çalışmalarda kullanılabilir.
Ao espelho – construção da auto-imagem em correspondências do fim de oitocentos
Authors: Morão Paula
Published: July 2023

Tanto privadas e sem intenção de publicar, como semi-públicas (sabendo que os correspondentes as publicarão), as cartas de escritores de finais do século XIX e de inícios do século XX merecem leitura atenta. São em muitos casos representativas de um retrato de época e de um pensamento estético elaborando-se e evoluindo; mas o auto-retrato e a edificação de uma figura de autor lê-se, de modo mais ou menos manifesto, nos epistolários. Trataremos de o comprovar lendo cartas de Antero de Quental e de António Nobre.
Diálogos epistolares de Jorge de Sena e João Gaspar Simões
Authors: Martins José Cândido de Oliveira
Published: July 2023

As cartas trocadas entre Jorge de Sena e João Gaspar Simões, entre 1943 e 1977, mostram-se bastante ricas em vários aspetos, apesar da sua escassez. As suas existências enquanto escritores e críticos literários têm alguns pontos de aproximação. Contudo, são muito mais as diferenças que os separam. Tudo isso explica o afastamento que aconteceu entre os dois intelectuais, superado por um reencontro final. O importante é o saldo desta correspondência, materializado no amplo interesse documental, em termos culturais e literários.
Ilse Losa e Maria da Graça Amado da Cunha: ligadas pelo comboio que leva as cartas e os boatos
Authors: Maurício Mariana
Published: July 2023

Ilse Losa (1913–2006), escritora que veio para o Porto para escapar ao regime nazi, e Maria da Graça Amado da Cunha (1919–2001), pianista e figura fundamental no meio cultural lisboeta, criaram uma amizade assente, em grande medida, na comunicação epistolar. Preenchendo com cartas o silêncio que intercalava os seus encontros, estas duas mulheres mantiveram-se unidas, ao longo de quarenta anos, graças ao comboio que ligava as duas cidades e levava as suas “cartas e boatos” (Cunha, 1953). A escritora e a pianista fundaram a amizade em afinidades políticas e intelectuais, conscientes da posição marginal que ocupavam no meio artístico e literário. As cartas e manifestações mútuas de apoio ajudaram a legitimar e validar as ambições e talentos artísticos de cada uma. Maria da Graça estabeleceu laços entre Losa e os escritores lisboetas que faziam parte do seu círculo próximo e empregou as suas capacidades literárias na leitura crítica dos livros de Ilse, com o objetivo de a ajudar a aperfeiçoar o uso da língua portuguesa e a escrita. Ilse, por sua vez, conhecendo as dificuldades que a amiga enfrentava na procura de estabelecer uma carreira como pianista, desejou contrariar o (talvez) inevitável fecho do piano por Maria da Graça.
Plínio-o-Moço e a dimensão multifacetada da sua correspondência
Authors: Soares Pereira Virgínia
Published: July 2023

O epistolário de Plínio-o-Moço constitui um legado clássico da maior relevância para o conhecimento do mundo romano de finais do século I e inícios do século II da nossa era. Entre o documental e o literário, as cartas plinianas permitem entrever o seu círculo familiar, político e literário, o seu núcleo de amigos, a sua filantropia, o apego à sua terra natal, a sua intervenção pública como advogado e senador, os seus cuidados como grande proprietário e senhor de escravos, bem como o seu gosto pelos mirabilia da natureza e a sua inesgotável curiosidade, além de uma imensa paixão pelos studia. Este artigo procurará dar a conhecer um epistológrafo amável e a sua visão multifacetada e amena do mundo circundante.
Risk factors for the development of discoordinated general activities as one of the variety of anomalies of uterus contractility during labor
Authors: Borshcheva A. A. , Pertseva G. M. , Alekseeva N. A.
Published: July 2023

Objective: to identify risk factors for the occurrence of discoordinated labor activity (DRD) and to conduct a comparative analysis of them in first- and repeat-bearing women.

   Materials and methods: the analysis of the course of pregnancy and the outcome of childbirth in 175 women with DRD was carried out. The cases of DRD over five years have been analyzed. All women underwent general clinical studies, ultrasound diagnostics (ultrasound), dopplerometry (DPM), cardiotocography (CTG).

   Results: functional disorders of the autonomic nervous system, morphological changes in the cervix, transferred FGM, as well as a combination of these types of pathology can be predictors of the development of DDD. There were no significant differences in the number of pregnant women suffering from NCD, having FGM, who suffered complications during pregnancy, as well as in the number of patients with prenatal and early discharge of amniotic fluid in the two groups. There are significant differences in the number of women with morphological changes in the cervix, they are significantly more in the second group. In women of the second group, significantly more often than in the first, delivery was performed by caesarean section.

   Conclusions: to reduce DRD in childbirth, in the process of pre-pregnancy preparation, it is necessary to identify risk groups, which will include pregnancy-planning patients with VSD, morphological changes in the cervix, VZHPO. These women should be recommended correction of the existing genital pathology. At the onset of pregnancy, patients with VSD should be recommended to undergo psychoprophylactic preparation for childbirth. These measures, in our opinion, will help to reduce the percentage of DRD, and reduce the overall percentage of delivery by caesarean section.
Modern approaches to the management of pregnancy in uterine myoma
Authors: Fatkullin I. F. , Orlov Y. V. , Fatkullin F. I.
Published: July 2023

The presented review summarizes current data on the tactics of accompanying patients with uterine myoma at various stages of their reproductive potential realization: the stage of pregravid preparation, the stage of pregnancy management, the moment of delivery and the postpartum period. Based on the analysis of domestic and foreign special scientific and practical literature, various methods of childbirth are proposed, from more preferable delivery through the natural birth canal, to the necessary caesarean section, performed strictly according to indications. Data are presented on the options for elective and emergency myomectomy during pregnancy, during operative delivery and in the postpartum period. Based on the results of systematization of the information received, the authors raise the question of the need for further research in the field of developing methods for optimal management of patients during pregnancy and childbirth complicated by uterine myoma, due to the relevance of the problems discussed.
Models of pathogenesis of psychosomatic disorders and the concept of psychosomatic scenario
Authors: Tolokonin A. O.
Published: July 2023

Currently, there is a significant prevalence of psychosomatic disorders: from 15 to 50% in the general population, 21-33 % in outpatient and 28-53% in inpatient somatic institutions. However, taking into account the variety of clinical manifestations of psychosomatic disorders and patients' seeking help not only from psychiatrists, but also from doctors of other specialties and representatives of nontraditional medicine, in reality these indicators are significantly higher. Untimely detection of the psychosomatic factor in the development of somatic disease often leads to the appointment of unreasonable and expensive treatment, including invasive interventions. The main cause of psychosomatic disorders is stress, prolonged exposure to which on the body leads to functional changes in the organs and their gradual destruction.

   Due to the high relevance of the problem of verification of psychosomatic disorders, the aim of this study was to develop an integrated approach to the diagnosis of psychosomatic diseases based on the analysis of existing concepts and notions; to achieve this goal, a literature review was conducted using Scopus, PubMed, Cochrane Library and CyberLeninka electronic libraries using keywords "psychosomatic disorder", "psychosomatics", "psychosomatic medicine".

   The concept of psychosomatic scenario of the disease (certificate of deposit No. 2207787) is suggested, based on combining the knowledge of classical western, Eastern medicine and psychotherapy, which allows the doctor to analyze, realize the psychosomatic scenario of the disease and see, what psychoemotional conflicts of the person himself and/or inherited from parents and ancestors, as well as distorted ideas about his present and future, was launched by the mechanism of adaptation to these distortions in the physical body in the form of a disease.
The Use of Virtual Reality Interventions to Promote Positive Mental Health: Systematic Literature Review (Preprint)
Authors: Li Pira Giorgio , Aquilini Beatrice , Davoli Alessandro , Grandi Silvana , Ruini Chiara
Published: July 2023

BACKGROUND

A large body of research has documented the efficacy of psychological interventions integrated with virtual reality (VR) therapies in treating psychiatric disorders. However, the concept of positive mental health calls for a 2-fold approach in which both symptoms and positive functioning should be addressed by modern interventions.

OBJECTIVE

This review aimed to summarize studies that applied VR therapies by embracing the positive mental health perspective.

METHODS

A literature search was conducted by entering the following keywords—“virtual reality” AND “intervention” OR “treatment” OR “therapy” AND “mental health” NOT “systematic review or meta-analysis”—and limiting it to “journal article” and the English language. To be included in this review, articles had to present at least one quantitative measure of positive functioning and one quantitative measure of symptoms or distress and had to investigate adult populations, including populations with psychiatric disorders.

RESULTS

A total of 20 articles were included. They described various VR protocols that were applied for the treatment of anxiety disorders (5/20, 25%), depression (2/20, 10%), posttraumatic stress disorder (3/20, 15%), psychosis (3/20, 15%), and stress (7/20, 35%). Most of the studies (13/20, 65%) showed the beneficial effects of VR therapies in improving stress and negative symptoms. However, 35% (7/20) of the studies showed no or a small effect on the various dimensions of positivity, particularly in clinical samples.

CONCLUSIONS

VR interventions might be cost-effective and largely scalable, but further research is needed to develop existing VR software and treatments according to the modern positive mental health approach.
Efficacy of an Internet-Delivered Intervention for Improving Insomnia Severity and Functioning in Veterans: Randomized Controlled Trial (Preprint)
Authors: Nazem Sarra , Barnes Sean M , Forster Jeri E , Hostetter Trisha A , Monteith Lindsey L , Kramer Emily B , Gaeddert Laurel A , Brenner Lisa A
Published: July 2023

BACKGROUND

Despite a growing evidence base that internet-delivered cognitive behavioral therapy for insomnia (iCBT-I) is associated with decreased insomnia severity, its efficacy has been minimally examined in veterans.

OBJECTIVE

The objective of this study was to evaluate the efficacy of an unguided iCBT-I (Sleep Healthy Using the Internet [SHUTi]) among veterans.

METHODS

We conducted a single-blind, randomized controlled trial in Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn veterans eligible for Veterans Health Administration care. Participants were randomly assigned (1:1) to receive SHUTi (a self-guided and interactive program) or an Insomnia Education Website (IEW) that provided nontailored and fixed insomnia information. Web-based assessments were administered at baseline, postintervention, 6 months postintervention, and 1 year postintervention. The primary outcome was self-reported insomnia severity (Insomnia Severity Index [ISI]). Secondary outcomes were self-reported mental and physical health functioning (Veterans RAND 36-item Health Survey). Exploratory outcomes comprised sleep diary parameters.

RESULTS

Of the 231 randomized participants (mean age 39.3, SD 7.8 years; 170/231, 73.5% male sex; 26/231, 11.3% Black; 172/231, 74.5% White; 10/231, 4.3% multiracial; and 17/231, 7.4% other; 36/231, 15.6% Hispanic) randomized between April 2018 and January 2019, a total of 116 (50.2%) were randomly assigned to SHUTi and 115 (49.8%) to the IEW. In intent-to-treat analyses, SHUTi participants experienced significantly larger ISI decreases compared with IEW participants at all time points (generalized η2 values of 0.13, 0.12, and 0.10, respectively; all P<.0001). These corresponded to estimated larger differences in changes of –3.47 (95% CI –4.78 to –2.16), –3.80 (95% CI –5.34 to –2.27), and –3.42 (95% CI –4.97 to 1.88) points on the ISI for the SHUTi group. SHUTi participants experienced significant improvements in physical (6-month generalized η2=0.04; P=.004) and mental health functioning (6-month and 1-year generalized η2=0.04; P=.009 and P=.005, respectively). Significant sleep parameter improvements were noted for SHUTi (all P<.05), though the pattern and magnitude of these reductions varied by parameter. No adverse events were reported.

CONCLUSIONS

Self-administered iCBT-I was associated with immediate and long-term improvements in insomnia severity. Findings suggest that leveraging technology to meet insomnia treatment demands among veterans may be a promising approach.

CLINICALTRIAL

ClinicalTrials.gov NCT03366870; https://clinicaltrials.gov/ct2/show/NCT03366870