bluuebunny/crossref_metadata_2025 huggingface dataset:
Immune mediated haemolytic anemia pada anjing siberian husky
Authors: Loisa . , Anggraini Nur Fitria , Khairunisa Talitha , Bahar Novri Wandi
Published: May 2018

Immune Mediated Haemolytic Anemia (IMHA) merupakan anemia yang muncul akibat hemolisis eritrosit di dalam pembuluh darah yang berhubungan dengan mediator sistem imun. Salah satu penyebab kondisi IMHA yaitu keberadaan parasit darah (Babesia sp.) dengan vektor caplak (Rhipicephalus sanguineus). Diagnosa IMHA yang disebabkan oleh infeksi Babesia sp pada anjing kasus ini terlihat melalui pemeriksaan sitologi dengan ditemukannya spherocyte dan terjadi hemolisis intravaskular sehingga masuk dalam kategori secondary IMHA. Pemeriksaan fisik di abdomen bagian kanan teraba adanya massa keras dan dilanjutkan pemeriksaan ultrasonografi dan radiografi. Hasil pemeriksaan ultrasonografi ditemukan adanya hepatomegali dan splenomegali.  Hasil radiografi bagian thoraks tampak adanya tromboemboli di paru-paru, sedangkan pada bagian abdomen menunjukkan adanya internal bleeding.  Berdasarkan hasil pemeriksaan darah menunjukkan rendahnya MCV dan MCHC (anemia mikrositik hipokromik oleh hemolisis), serta peningkatan RBC yang disebabkan oleh produksi RBC (eritrogenesis) khususnya retikulosit. Infeksi Babesia sp. pada anjing ini tampak pada tingginya persentase granulosit.  Kejadian IMHA merupakan kondisi kronis, sehingga untuk mencegah IMHA diperlukan edukasi secara menyeluruh mengenai bahaya dampak infeksi ektoparasit (tick dan fleas) dalam jangka panjang dan cara mengendalikan ektoparasit.
Pengendalian Mutu Pada Proses Produksi Di Tiga Usaha Kecil Menengah Tahu Kabupaten Bogor
Authors: Sonalia Devi , Hubeis Musa
Published: May 2018

Today the growth of Small and Medium Enterprises (SMEs) is increasing significantly along with the rise in competitiveness in this field. Accordingly entrepreneurs who want to get into the competition and do not want to be left behind by other SMEs in the business field have to pay attention to the quality of their product. The purpose of this study are: (1) to analyze the quality control (QC) on the production process in SMEs of Tofu (soybean cake) as Tahu  Bambu, Tahu Bandung Ashor and Tahu Bandung; (2) to  identify the factors which cause damage of Tofu as Tahu Bambu, Tahu Bandung Ashor and Tahu Bandung; (3) to identify the most influential factor affecting  the quality  of Tofu as Tahu Bambu, Tahu Bandung Ashor and Tahu Bandung; and (4) to assess the QC on the production process in the above three unit. The data used in this study were primary and secondary data. Primary data were obtained through direct observation and interviews with the SMEs, while the secondary data were taken from the internet and references such as books, journals and theses. Analysis tool used were Pareto Diagram, Cause and Effect Diagram and Control Chart. It is from Cause-Effect diagram that the factors affecting damage in three SMEs of Tahu were revealed, i.e human, raw materials, machines and tools, methods and environment with the main cause of most influence through analysis Pareto diagram is one piece. Quality control of the SMEs Tahu Bambu and SMEs Tahu Bandung  analyzed using by p Control Charts indicated that they were controlled.

Keywords: Quality controls, Cause and effect diagram, Pareto chart, Control chart
Analisis Beban Kerja Sumber Daya Manusia dalam Aktivitas Produksi Komoditi Sayuran Selada (Studi Kasus: CV Spirit Wira Utama)
Authors: Adawiyah Wildanur , Sukmawati Anggraini
Published: May 2018

CV Spirit Wira Utama is a company that develops business model of agricultural (agribusiness) with hydroponic system without using greenhouse (open roof). The aims of this research are: (1) to  identify the Human Resources Development working description in producing lettuce, and (2) to  analyze the ideal number of employees based on employee workloads by counting Full Time Equivalent (FTE). Human Resources Development that supports in production process of lettuce commodity are divided  into the involved in off-farm and on-farm activities. The off farm activities includes technique, production, finance and marketing. Otherwise, on farm activity includes garden employees. The result of the research shows working time of Human Resource Development has not been optimal. Furthermore, to reach the effectiveness and efficiency an  alternative that can be carried out by a company is by combining the technique and production positions, job enlarging of finance and marketing positions, and improving the production phase of lettuce.

Keywords: employee needs, FTE, hydroponic, lettuce, workload analysis
Analisis Persepsi Konsumen dan Strategi Pemasaran Beras Analog (Analog rice)
Authors: Rizki Deviany Amanda , Munandar Jono M. , Andrianto M. Syaefudin
Published: May 2018

Analog rice is artificial ricewhose material is not from paddy, but it is made from a variety of local flour (corn, sago and shorgum). As a new product, Rice Analog require appropriate marketing strategies through analysis of consumer perception. This research purposes are to develop a marketing strategy through identification Analog Rice segmentation, targeting and positioning based on consumer perception. The analytical method used were crosstabs analysis, cluster analysis and biplot analysis with 73 respondent. Crosstabs result indicated that consumer characteristics (age, marital status, education, income and expenses of month), associated with their impression and interested  to re-purchase. Cluster analysis was delivered into four market segments, the third target market are 31-40 years old, married, the level of income of IDR 4,500,001 to IDR 6,000,000. Biplot analysis deliver positioning for Analog Rice product therefore this rice offers “health benefits”, “nutritive ingredients”, and “safe to consumed”.
Keywords : Analog rice, consumer perceptions, marketing strategy, cluster analysis, biplot analysis.
Pengaruh Motivasi Kerja terhadap Kinerja Karyawan Wilayah Telkom Jabar Barat Utara (Witel Bekasi)
Authors: Larasati Sindi , Gilang Alini
Published: May 2018

Sumber daya manusia (SDM) penting bagi perusahaan karena memiliki peran sebagai potensi penggerak seluruh aktivitas perusahaan. Perusahaan yang memiliki SDM yang berkualitas dapat dengan mudah mengintegrasikan visi perusahaan dengan tujuan perusahaan kepada karyawannya sehingga pencapaian tujuan perusahaan bisa tercapai. Penelitian ini dilakukan di Wilayah Telkom Jabar Barat Utara (Witel Bekasi) dengan menggunakan motivasi kerja sebagai variabel independen dan kinerja sebagai variabel dependen. Tujuan penelitian ini untuk mengetahui bagaimana pengaruh motivasi kerja yang terdiri dari kebutuhan prestasi, kebutuhan afiliasi dan kebutuhan kekuasaan terhadap kinerja karyawan Witel Bekasi. Penelitian ini merupakan penelitian deskriptif dan kausal. Analisis data yang digunakan adalah analisis deskriptif, analisis regresi linier berganda, uji hipotesis secara simultan (uji F), uji hipotesis secara parsial (uji t), dan koefisien determinasi. Teknik sampel yang digunakan adalah Proportionate Stratified Random Sampling. Berdasarkan hasil kuesioner dengan 180 orang responden, penilaian karyawan terhadap motivasi kerja dan kinerja termasuk dalam kategori sangat tinggi. Pada hasil pengujian hipotesis dapat disimpulkan bahwa variabel Motivasi Kerja (X) yang  terdiri dari Kebutuhan Prestasi (X1), Kebutuhan Afiliasi (X2) dan Kebutuhan Kekuasaan (X3) secara simultan dan parsial berpengaruh signifikan terhadap Kinerja Karyawan (Y). Pada hasil uji koefisien determinasi (R2) diperoleh nilai sebesar 0.551. Hal ini berarti bahwa besarnya pengaruh motivasi kerja terhadap kinerja karyawan adalah sebesar 55.1%, sedangkan sisanya 44.9% dipengaruhi faktor-faktor lain yang tidak diteliti dalam penelitian ini.
Kata kunci: motivasi kerja, kinerja karyawan, sumber daya manusia, human capital, witel bekasi.
Analisis Pengendalian Mutu Jambu Kristal dengan Metode Six Sigma di ADC IPB-ICDF Taiwan, Bogor
Authors: Pratidina Raisha , Syamsun Muhammad , Wijaya Nur Hadi
Published: May 2018

Manajemen mutu merupakan salah satu kunci sukses perusahaan untuk memenangkan pasar dan mencapai tujuaannya. Begitu juga yang harus dilakukan oleh Agribussiness Development Center (ADC) Institut Pertanian Bogor (IPB)-Taiwan International Cooperative Development Fund (ADC IPB-ICDF Taiwan). Produk unggulan dari perusahaan adalah jambu Kristal yaitu buah dengan biji yang sedikit, rasa manis dan renyah. Tahun 2012, perusahaan hanya mampu memenuhi sebesar 31% permintaan pasar atas jambu Kristal grade A, serta grade B+, B dan C mencapai 69%. Metode analisis yang digunakan adalah Analisis Defect per Opportunity (DPO), Analisis Defect per million Opportunity (DPMO), Diagram alir proses (Process Flow Diagram), Diagram pareto (Pareto Chart), Peta kendali, Diagram Sebab Akibat (Fishbone Diagram), Failure Mode and Effect Analysis (FMEA) dan Metode Six Sigma. Berdasarkan hasil analisis, terdapat enam Critical To Quality (CTQ) antara lain pembibitan, kondisi lingkungan, pemupukan, perawatan, panen dan pasca panen. Hasil perhitungan kapabilitas sigma selama tahun 2012 masih berada kisaran 2-sigma. Hal ini menunjukkan masih banyak defect dan kapabilitas sigma berada di bawah target (3,4 DPMO). Dengan demikian, untuk saat ini ADC IPB-ICDF Taiwan, Bogor masih belum realistis untuk mengaplikasikan six sigma dikarenakan produk agribisnis yang rentan dan dipengaruhi oleh berbagai faktor alam yang sulit untuk dikendalikan.Kata kunci : jambu Kristal, pengendalian mutu, six sigma
Pengaruh Persepsi dan Preferensi Konsumen terhadap Keputusan Pembelian Hunian Green Product
Authors: Wardhani Widya , Sumarwan Ujang , Yuliati Lilik Noor
Published: May 2018

Tujuan dari penelitian ini adalah: 1) Mengidentifikasi faktor-faktor yang mempengaruhi persepsi konsumen terhadap keputusan pembelian green product hunian; 2) Mengidentifikasi faktor-faktor yang mempengaruhi preferensi konsumen keputusan pembelian green product hunian; 3) Menganalisis pengaruh persepsi konsumen dan preferensi keputusan pembelian green product hunian. Data yang diperoleh dari 151 responden dibagi menjadi dua kelompok yaitu kelompok penghuni dan kelompok non penghuni. Dalam penelitian ini, dikembangkan model dengan 30 indikator (27 indikator eksogen, 3 indikator endogen). Data dianalisis dengan Analisis Partial Least Square menggunakan program SmartPLS. Kesimpulan dari penelitian ini adalah variabel produk, fasilitas, citra pengembang, metode pembayaran dan lingkungan memiliki pengaruh yang signifikan terhadap keputusan pembelian green product hunian, sementara variabel harga, promosi, dan faktor sosial tidak berpengaruh secara signifikan.Kata kunci :           keputusan pembelian, partial least square, persepsi konsumen, preferensi konsumen, produk ramah lingkungan
Dampak Reformasi Birokrasi pada Perubahan Budaya Organisasi di Perwakilan BPKP Provinsi DKI Jakarta
Authors: Aridhona Nina , Baga Lukman M. , Affandi M Joko
Published: May 2018

Various changes in the strategic environment have forced the public sector to make bureaucratic reform that should have consequences on changing the bureaucratic culture in the public sectorsto be more externally oriented culture. Financial and Development Supervisory Agency (BPKP) is an internal control government agency that should change the organizational culture. The needsforexternally oriented culture was now even stronger in line with the shift in the role from watchdog to become in-house consultant. Therefore, this study aims to analyze organizational culture changes and identify the factors that cause or inhibit changes. This study used competing values framework, a method that is able to capture the changes of organizational cultures, both large and direction. The research result showed that organizational culture has been transformed from hierarchy culture to market culture. These changes indicatedthe organizational culture has been changed in accordance with the concept of bureaucratic reform. However, the changes in organizational culture were not significant. Employee resistance and the policy of change that is not the same in all aspects of organizational were known as the factors inhibiting organizational culture changes.Key word: bureaucratic reform, competing values framework, organizational change, organizational culture, public sector
Identificación de nuevas mutaciones en TCIRG1 como causa de osteopetrosis maligna infantil en dos pacientes mexicanos
Authors: Hernández-Martínez Claudia , Guzmán-Martínez Mara Noemí , Scheffler-Mendoza Selma , Espinosa-Padilla Sara Elva , Sobacchi Cristina , Blancas-Galicia Lizbeth
Published: May 2018

Antecedentes: La osteopetrosis es un grupo heterogéneo de enfermedades que se caracterizan por aumento de la densidad ósea debido a anomalías en la diferenciación o función de los osteoclastos, lo que se traduce en falta de reabsorción ósea.Reporte de casos: Dos pacientes con osteopetrosis quienes iniciaron su padecimiento desde los primeros meses de vida, con dismorfia facial, ceguera, sordera, hepatoesplenomegalia, hipotonía, retraso del neurodesarrollo y bicitopenia. Las radiografías óseas mostraron osteoesclerosis. Fueron valorados por diversos especialistas antes del diagnóstico definitivo. El análisis genético determinó mutaciones en el gen TCIRG1. En el paciente 1 se identificó una mutación homocigota para p.Ile720Alafs*14, la cual no ha sido reportada. En el paciente 2 se registró una mutación heterocigota compuesta: la primera p.Phe459Leufs*79 y la segunda p.Gly159Argfs*68, ninguna de las cuales han sido descritas hasta donde tenemos conocimiento.Conclusión: La única opción terapéutica de los pacientes con osteopetrosis es el trasplante de células progenitoras hematopoyéticas (TCPH), que se debe realizar en el transcurso de los primeros tres meses de vida, antes de que se origine daño neurológico. Si bien el diagnóstico de osteopetrosis es relativamente sencillo, se retrasa debido a la falta de sospecha clínica.
PENGARUH PRODUK DOMESTIK BRUTO DAN INFLASI TERHADAP INDEKS HARGA SAHAM GABUNGAN DI BURSA EFEK INDONESIA TAHUN 2002-2009
Authors: Prasetyanto Panji Kusuma
Published: May 2018

This study aims to determine (1) Effect of Gross Domestic Product on Stock Price Index (IHSG) in Indonesia Stock Exchange (BEI) in 2002 to 2009, (2) Effect of Inflation on Stock Price Index (IHSG) in Indonesia Stock Exchange (BEI) in 2002-2009. The population in this study is the price index of all shares listed on the Stock Exchange (BEI) from 1 January 2002 until 31 December 2009. The samples in this study using saturation sampling or sample census. Data collection technique used documentation techniques. Analysis of the data in this study using four types of test, namely: (1) descriptive statistics, (2) the classical assumption, (3) a regression test and (4) test the hypothesis. This study using SPSS version 17.0 for data processing. The results showed that (1) the Gross Domestic Product significant positive effect on the t-count IHSG 10.793 and 0.000 significance, (2) Inflation had no significant effect on IHSG by t-test 1.942 and 0.062 significance.
PEMODELAN PETA MATERIALITAS INFORMASI PADA LAPORAN KEBERLANJUTAN PERUSAHAAN (Suatu Tinjauan Mengenai Pelaporan Keberlanjutan Industri Perbankan di Indonesia)
Authors: Kurniawan Putu Sukma
Published: May 2018

Corporate sustainability report has become a new paradigm in the evolution of corporate reporting. This study aims to create a map of information materiality contained in the sustainability report of the banking industry in Indonesia.The method used is analyze content of sustainability reports of the banking industry in Indonesia. Data collection is done by looking for secondary data through page of Indonesia Stock Exchange or company official website. Data analysis was done descriptively by analyzing the contents of sustainability report. The analysis is done by comparing the contents of the sustainability report with the disclosure items contained in the GRI G4 reporting standard (Fourth Generation of Global Reporting Initiative), especially in GRI G4 Sector Disclosures Financial Services.The results of this study produce maps containing material information in the sustainability report of the banking industry. The results of this study may contribute to the management of the company to identify the material information that can be submitted to the company's stakeholders. Keyword : Map of Information Materiality, Sustainability Reporting, Sustainability Report, Banking Industry
Heat flow in Rajasthan Craton, North–Western Indian Shield and its Implications
Authors: Gupta Mohan Lal , Sharma Shadi
Published: May 2018

A synthesis and reinterpretation of surface heat flow values of the Rajasthan Craton(RC), north-western Indian Shield has been carried out. The results reveal that the q values are relatively high, varying from 52 to 96 mWm-2. Appreciable variations in the magnitude of q are found between and within its geotectonic units, but with considerable overlap of values. Paleo–Meso Proterozoic Aravalli Super Group is generally associated with high q values, varying from 52 to 67 mWm-2, with a mean value of 60 mWm-2. Values of still higher order varying from 52 to 76 mWm-2 occur in North Delhi Fold Belt of Meso–Neo Proterozoic Delhi super Group, Tusham area, which is located towards north west corner of the Delhi Fold Belt in the Trans-Aravalli Province of RC, is characterized by a very high heat flow value. This is the highest of all heat flow values so far reported for the Proterozoic terrains of the Indian Shield, which is ascribed as due both to enhanced crustal radioactivity and renewed tectonic activity beneath its region. The heat flow values reported in areas of the Delhi Super Group and Aravalli Super Group are of short wavelength, naturally these are due to shallow sources. We infer that these are mostly due to varying degrees of concentration of heat producing elements in the upper crust. There are also no evidences of major tectono-thermal events after the Neo-Proterozoic times (~600Ma) in the study area. Hence, we conclude that observed variations in heat flow do not carry thermal transients of any recent tectonic activity.
International Heat Flow Commission: History and Accomplishments over the last fifty-five years
Authors: Cermak Vladimir , Beck Alan , Hamza Valiya
Published: May 2018

The study of the earth's internal heat plays an important role in understanding the Earth's origin, internal constitution, and plate tectonics. The outflow of heat from the Earth's interior is, energy-wise, the most impressive terrestrial phenomenon. The present rate of heat loss is estimated to be about 1021 joules per year, which is orders of magnitude greater than the energy dissipation of earthquakes or heat loss from volcanic eruptions. Knowledge of terrestrial heat flow is essential in investigating the internal thermal field of the Earth. Initially focus has been on measurements of underground temperatures and thermal properties of geologic materials, assessment of sources and sinks of heat, institution of global data base, development of thermal models of crust and qualification of geothermal energy resources. During later stages, other implications of heat flow studies has also been recognized in fields such as paleoclimatology, global warming, exploration geophysics and hydrogeology. The International Heat Flow Commission – IHFC plays a guiding role in development of such investigations.
Heat Flow, Geotherms, Density and Lithosphere Thickness in SW of Iberia (South of Portugal)
Authors: Duque Maria Rosa Alves
Published: May 2018

Thermal structure, density distribution and lithosphere thickness in the SW part of the Iberian Peninsula are studied using data obtained in the South Portuguese Zone (SPZ) and SW border of the Ossa Morena Zone (OMZ) in the South of Portugal. Five different regions were defined, and models were built for each region. Geotherms were obtained using average density values from data published. The high values of heat flow density in these regions are attributed to occurrence of anomalous heat sources due to radioactivity content and exothermic chemical reactions associated to ore deposits in the zone. The results obtained with models based on isostasy in the region led to lithosphere thickness values between 95 and 96 km in the SPZ and a lower value of 94.5 km in the SW border of the OMZ. Analysis of geotherms shows lateral variations of temperature at the same depth. These lateral variations are compared with information obtained with seismic data.
Hangman’s Fracture and Its Management
Authors: Singh Anish M , Shrestha Prabin
Published: May 2018

Not available.Nepal Journal of Neuroscience, Volume 14, Number 2, 2017, Page: 31-31
Balloon Test Occlusion for an Option to Decide Whether Simple ICA Ligation is Better Option than Trapping and High Flow Bypass of The Giant ICA Cavernous Aneurysm
Authors: Rajbhandari Saujanya , Rajbhandari Pravesh , Shrestha Pranaya , Pant Basant , Neupane Anish
Published: May 2018

Balloon Test occlusion (BTO) is a preoperative angiographic test used to estimate the risk of stroke after permanent therapeutic occlusion of an internal carotid artery (ICA) involved by aneurysms. Temporary balloon occlusion at the cavernous ICA aneurysm neck was performed in an attempt to assess the adequacy of cross flow from the opposite ICA. Adequate fl ow following BTO are preferred to have simple ICA ligation and incase of those who did not pass BTO trapping and high flow bypass is preferred .We have done Right ICA Ligation on our case report.Nepal Journal of Neuroscience, Vol. 14, No. 2,  2017 Page:32-35
A Giant Solitary Solid Hemangioblastoma: A Case Report and Review of The Literature
Authors: Bhandari Rajeev , Sharma Gopal R , Bista Prakash , Jha Rajiv , Shrestha Rajendra , Poudel Prakash
Published: May 2018

We present a case of solitary vascular tumor on posterior cranial fossa in a 15-year-old female who had a complaint of headache on/off for six months with associated dizziness, nausea, vomiting and vertigo. Well circumscribed solid vascular mass was localized on posterior fossa by computed tomography along with magnetic resonance imaging scan. Furthermore, the diagnosis was confirmed by surgical findings and histological examinations.Nepal Journal of Neuroscience, Vol. 14, No. 2,  2017 Page: 47-50
INVENTARISASI TUMBUHAN BAWAH DI KAWASAN HUTAN TAMAN WISATA ALAM SIBOLANGIT, KABUPATEN DELI SERDANG
Authors: Puspita Sari Wina Dyah , Aryeni Aryeni
Published: May 2018

Underwater plants are plants in the form of herbaceous plants and shrubs and low plants that cover the bottom of a forest area. Thus the function of the plant here is to withstand the destructive power of the falling rain fall and the rapid flow of water above the soil surface. Sibolangit Nature Park is a forest area with an area of Â± 24.85 Ha. The existence of the lower plants in Sibolangit Nature Park become the main attraction for the visitors. The purpose of the research is to obtain the inventory data of the lower plants and describe the characters morphology. The research was conducted by using the exploration method along the path of Sibolangit Nature Park. From the research that has been done, there are 48 types of plants that consist of 31 families. Of the 48 undersea species identified, 30 of them belong to the Spermatophyta division, while the remaining 18 are included in the Pterydophyta division.Underwater plants are plants in the form of herbaceous plants and shrubs and low plants that cover the bottom of a forest area. Thus the function of the plant here is to withstand the destructive power of the falling rain fall and the rapid flow of water above the soil surface. Sibolangit Nature Park is a forest area with an area of Â± 24.85 Ha. The existence of the lower plants in Sibolangit Nature Park become the main attraction for the visitors. The purpose of the research is to obtain the inventory data of the lower plants and describe the characters morphology. The research was conducted by using the exploration method along the path of Sibolangit Nature Park. From the research that has been done, there are 48 types of plants that consist of 31 families. Of the 48 undersea species identified, 30 of them belong to the Spermatophyta division, while the remaining 18 are included in the Pterydophyta division.
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SANGITAN (Sambucus javanica Reinw) TERHADAP PERTUMBUHAN BAKTERI Eschericia coli DAN Salmonella thypi
Authors: Dasopang Eva Sartika
Published: May 2018

Leaves of sangitan (Sambucus javanica Reinw) are often found but noticed. The leaf part of the sangitan plant is used to treat swelling, insecticides, antidiarrheal, antiinfectives, wounds, smoothing the skin as it contains flavonoid chemical compounds, glycosides, anthracton glycosides, saponins, steroids / triterpenoids and tannins. Screening results of ethanol extract of sour leaves (SambucusjavanicaReinw) contain alkaloid compounds, flavonoids, glikosida, antrakinon glycosides, saponins, steroids / triterpenoids and tannins. The extraction of sangitan leaves was done by maceration using 96% ethanol. Examination of antibacterial activity of ethanol extract of sangitan leaves was done in vitro by diffusion method of wells with concentrations of 500, 400, 300, 200 and 100 mg / ml. This study used cotrimosazole as a comparator and 96% ethanol as a negative control. The extract of ethanol leaves sangitan showed anti bacterial activity against bacteria Eschericia coli and Salmonella thypi at concentration 500 mg / ml respectively 16,11 mm and 17,04 mm which is classified strong but when compared with antibiotic cotrimosazole 10 mg / ml visible diameter of inhibit ethanol extract Leaves sangitan still much lower that is 30,35 mm in bacterium Eschericia coli and 33,15 mm in Salmonella thypi bacteria whereas ethanol extract do not show inhibitory power.
PENGGUNAAN TANAMAN AREN PADA UPACARA SIPAHA LIMA MASYARAKAT PARMALIM
Authors: Z.N.A Hanifah Mutia
Published: May 2018

The purpose of this research are to know the beneficiaries and symbols contained in sugar palm plants in traditional ceremony Sipaha Lima. The method used in this research are the method of observation and depth interview. The data obtained in the form ofÂ  plant parts used, how to obtain it and the meaning of symbol of the plant.The results is obtained eight types of use of sugar palm in traditional ceremony Sipaha Lima. Part of the plants used are: stems, leaves, and midrib. These plants are obtained from forests and crops.
PENGARUH KADAR ASAM SULFAT PADA HIDROLISIS TANDAN KOSONG KELAPA SAWIT (TKS) DAN WAKTU FERMENTASI TERHADAP KADAR BIOETANOL YANG DIHASILKAN
Authors: Sartini Sartini , Fitriani Rita , Lubis Rosliana
Published: May 2018

The effect of sulphuric acid fermentation of processed palm oil bunch hydrolysis and on ethanol and sugar production was conducted. The aim was to investigate the hydrolytic optimum required by Saccharomyces cerevisiae for ethanol and sugar production. About 12.5 g powdered palm oil bunch was used in this experiment. The powder was hydrolized several times using sulphuric acid in several concentration. Sugar, product ofÂ  hydrolysis, was detected every one hour using spectrophotometer. The sugar was fermented by Saccharomyces cerevisiae and incubated for several days. Results showed that 2-4% sulphuric acid was oprimum concentration for 30 g/L sugar production. The highest ethanol production 4.94% occurred after two days fermentation.
KUALITAS SPERMATOZOA DAN INDEKS FERTILITAS TIKUS PUTIH DEWASA (Rattus novergicus L.) SETELAH PEMBERIAN EKSTRAK DAUN WUNGU (Graptophyllum pictum. L.Grifft)
Authors: Pranoto Hendro
Published: May 2018

This research objective is to identify the effects of wungu leaf extract (Graptophyllum pictum L. Griff) on the fertility index and spermatozoa of normal morphology in male rat ( Rattus novergicus.L). Fifteen male and 45 female rats of 9 to 10 weeks old were used as research samples. The fifteen male rats were divided into five treatment groups of wungu extract dosage: control I (0mg/KgBW), control II (0.5ml olive oil), dosage 1 (100mg/KgBW), dosage 2 (200mg/KgBW), and dosage 3 (400mg/KgBW) for 60 days. The extract was given orally and each group consisted of three test rats as repetition. On the day 55 to day 60, each test male animal was mated with three female rats. After 60 days, an observation was done to 15 male and 45 female rats to identify fertility index. Normal spermatozoa morphological observation with microscope. The data obtained were tested by Analysis of Variance Test (ANOVA ? = 0.05) and Duncanâ€™s Multiple Range Test (DMRT). Based on the observation and statistical analysis, it was found that wungu leaf extract of different dosages did not give significant effects on fertility index but have significant effects on spermatozoa of normal morphology. This was proven by the fact that the higher the dosage given, the worse the spermatozoa of normal morphology. Based on Linear Regression Analysis, it was found significant correlation between dosage variation extract of wungu leaf and fertility index, and number of normal spermatozoa.
Biotransformasi Tartrazin oleh Bakteri Usus Manusia
Authors: Batubara Melvariani Syari , Ginting Nurmaini
Published: May 2018

The aimed of this research was to investigated human intestinal bacteria (Streptococcus faecalis, Eschericia coli, Salmonella Sp., and Vibrio fischeri), to investigated dose of tartrazine, and to investigated biotransformation of tartrazine by human intestinal bacteria (Streptococcus faecalis, Eschericia coli, Salmonella Sp., and Vibrio fischeri). The method of this research was experiment with significant correlation to investigated biotransformation of tartrazine by human intestinal bacteria (Streptococcus faecalis, Eschericia coli, Salmonella Sp., and Vibrio fischeri). This study is primarily focussed on made bacteria medium, made standart inoculums of bacteria, and evaluation for activity of human intestinal bacteria (Streptococcus faecalis, Eschericia coli, Salmonella Sp., and Vibrio fischeri). The results obtained were attributed to the human intestinal bacteria was used in this research was biotransformated tartrazine. From the results that had been increase dose of tartrazine correlation with increase biotransformation by human intestinal bacteria. Highest dose of tartrazine was 15 mg, and highest biotransformation by Vibrio fischeri, which rate of zone decolourisation diameter was 1,22 cm, and rate of zone decolourisation was 1,44 cm2. Statistically showed significantly in correlation dose of tartrazine with rate of zone decolourisation (0,001 < P < 0,05), but statistically showed non significantly in correlation bacteria with rate of zone decolourisation (0,05 < P < 0,268).
Pemasaran Politik Bupati Bima Terpilih Pada Pilkada Kabupaten Bima Tahun 2015
Authors: Nurfitriani Nurfitriani , Hamrun Hamrun , Taufik Ahmad
Published: May 2018

Pemasaran politik merupakan hal yang sangat penting dilakukan dalam suatu pemilihan karena dapat membantu efektifitas penyusunan produk politik, serta dapat menyampaikan produk politik tersebut secara luas kepada masyarakat. Pemasaran politik akan membawa manfaat baik itu bagi partai politik ataupun kandidat pasangan calon karena dengan adanya pemasaran politik hubungan mereka dengan pemilih akan terbangun dan secara tidak langsung dapat memberikan manfaat bagi masyarakat yang merupakan konsumen politik. Jenis penelitian ini adalah deskriptif kualitatif sehingga dapat menjelaskan obyek penelitian di kantor Bupati Bima dan kantor  KPU Kabupaten Bima. Data dan informasi  yang dibutuhkan dalam penelitian ini diperoleh dari informan. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah dengan melakukan observasi langsung dilokasi penelitian dan wawancara secara mendalam, dan dokumentasi. Data tersebut dianalisis melalui reduksi data yaitu merangkum dan fokus pada hal yang penting kemudian dilakukan penarikan kesimpulan.Hasil penelitian menunjukan bahwa pemasaran politik yang dilakukan oleh Bupati Bima terpilih belum efektif karena ada beberapa permasalahan yang di anggap sebagai faktor penghambat pada saat melakukan pemasaran politik.
Open Innovation im Mittelstand
Authors: Stemplinger Christian T. , Voss Kimberly-Roxanne
Published: May 2018

Kurzfassung

Der immer stärker werdende Innovationsdruck auf Unternehmen hat mittlerweile auch die kleinen und mittleren Unternehmen (KMU) erreicht und stellt diese vor neue Herausforderungen. Der vorliegende Beitrag zeigt anhand einer qualitativen Befragung, wie Betroffene und Experten die Chancen und Risiken dazu einschätzen. Eine anschließende Evaluation und Interpretation der Ergebnisse ermöglicht einen anwendungsorientierten Lösungsansatz für ein Open Innovation Konzept für die KMU inklusive eines Implementierungsleitfadens.
Durchgängige modellbasierte Bewertung von Regenerations-lieferketten
Authors: Lucht Torben , Schäfers Philipp , Nyhuis Peter
Published: May 2018

Kurzfassung

Die Optimierung der Logistikleistung sowie der Logistikkosten sind zentrale Ziele der Regeneration komplexer Investitionsgüter. Aufgrund von Komplexität und interdependenten Wirkbeziehungen sind die Auswirkungen unterschiedlicher Konfigurationen von Regenerationslieferketten auf die logistischen Zielgrößen derzeit nicht prognostizierbar. Im Rahmen des SFB 871 wird am Institut für Fabrikanlagen und Logistik (IFA) daher ein Bewertungsmodell entwickelt, um die individuelle Gestaltung und Optimierung von Regenerationsprozessen für komplexe Investitionsgüter zu unterstützen.
Influence of the carbon content on the microstructure and properties of heat-resistant cast steels
Authors: Rongeat Carine
Published: May 2018

Two heat-resistant ferritic cast steels, 1.4476 and 1.4777 with a similar high Cr concentration, have been analyzed regarding their microstructures, mechanical properties, corrosion resistance and aging behavior. The differences observed between the grades are related to their different C contents. A higher C concentration ensures a higher mechanical resistance, in particular at high temperature (850°C) and also a better high-temperature (850°C) corrosion resistance. This is related to the formation of numerous carbides. However, this study also reveals that the microstructure of these steels is greatly affected by aging. In particular, the precipitation of the sigma phase and the formation of nitride precipitates could lead to failure during service at high temperature.
Dissimilar TIG Welding of HSLA to Austenitic High-Mn TRIP Steels
Authors: Buzolin R. H. , Rodrigues J. A. , Da Silva E. Pereira , Maluf O. , Pinto H. Cavalcanti
Published: May 2018

The microstructure and mechanical properties of dissimilar butt-joints of high-strength low-alloy steel to austenitic high Mn TRIP steels produced by manual TIG welding with AISI 309L filler metal were investigated. The heat input was varied by changing the welding current between 40 and 70 A. A fully austenitic microstructure with nearly equiaxed grains and without any iron/manganese carbide is observed in the high Mn TRIP base metal, whereas polygonal ferrite and pearlite colonies oriented along the rolling direction are found in the high-strength low-alloy steel base metal. Coarse and refined heat-affected zones (HAZ) were observed in the high-strength low-alloy steel, whereas no significant HAZ was detected at the TRIP side. Bainite and/or martensite grew in the coarse HAZ of the high-strength low-alloy steel steel joined with highest current. The weld seam was formed by austenitic dendrites with interdendritic ferrite and martensite. The best welding condition was achieved with an intermediate current of 50 A, where the hardness transition was smooth, fracture occurred in the HSLA base metal and the joint ductility was higher.
Ideas of Poetics and the Close Reading of Poetry
Authors: Hart Jonathan Locke
Published: May 2018

Ranjan Ghosh and J. Hillis Miller provide different but productive ways to think about poetics and to read poetry closely and with attention. As a poet, reader and critic of poetry, I welcome their thoughts on the theory and practice of poetry. Whereas Miller sees the reading of poems as subjective and selective, Ghosh views it as universal and shared. Both readers help us in the drama of meaning, the tension between them. As convivial and suggestive as that difference between Miller and Ghosh may be, it allows us to experience the different sides of poetry and the philosophy of poetry, if we think about, say the Socratic, Platonic, and Aristotelian tradition of thinking about poetry and even Philip Sidney's response on the one hand and the rhetorical tradition of reading poetry on the other. Ghosh, although having mastered Western literature and poetry, as Miller has, also provides us with Eastern views, and this is also of great benefit to the reader of Thinking Literature Across Continents ( 2016 ). One of the great centres of literature is language and poetry is compressed and memorable language that forms the heart of literature: it is a key to thinking about Ghosh and Miller thinking literature across the various parts of the world.
The Average Hazard Ratio – A Good Effect Measure for Time-to-event Endpoints when the Proportional Hazard Assumption is Violated?
Authors: Brannath Werner , Brückner Matthias , Kieser Meinhard , Rauch Geraldine
Published: May 2018

Background: In many clinical trial applications, the endpoint of interest corresponds to a time-to-event endpoint. In this case, group differences are usually expressed by the hazard ratio. Group differences are commonly assessed by the logrank test, which is optimal under the proportional hazard assumption. However, there are many situations in which this assumption is violated. Especially in applications were a full population and several subgroups or a composite time-to-first-event endpoint and several components are considered, the proportional hazard assumption usually does not simultaneously hold true for all test problems under investigation. As an alternative effect measure, Kalbfleisch and Prentice proposed the so-called ‘average hazard ratio’. The average hazard ratio is based on a flexible weighting function to modify the influence of time and has a meaningful interpretation even in the case of non-proportional hazards. Despite this favorable property, it is hardly ever used in practice, whereas the standard hazard ratio is commonly reported in clinical trials regardless of whether the proportional hazard assumption holds true or not.

Objectives: There exist two main approaches to construct corresponding estimators and tests for the average hazard ratio where the first relies on weighted Cox regression and the second on a simple plug-in estimator. The aim of this work is to give a systematic comparison of these two approaches and the standard logrank test for different time-toevent settings with proportional and nonproportional hazards and to illustrate the pros and cons in application.

Methods: We conduct a systematic comparative study based on Monte-Carlo simulations and by a real clinical trial example.

Results: Our results suggest that the properties of the average hazard ratio depend on the underlying weighting function. The two approaches to construct estimators and related tests show very similar performance for adequately chosen weights. In general, the average hazard ratio defines a more valid effect measure than the standard hazard ratio under non-proportional hazards and the corresponding tests provide a power advantage over the common logrank test.

Conclusions: As non-proportional hazards are often met in clinical practice and the average hazard ratio tests often outperform the common logrank test, this approach should be used more routinely in applications.
Analysis of Instantaneous Linear, Nonlinear and Complex Cardiovascular Dynamics from Videophotoplethysmography
Authors: Iozzia Luca , Cerina Luca , Mainardi Luca , Barbieri Riccardo , Valenza Gaetano
Published: May 2018

Background: There is a fast growing interest in the use of non-contact devices for health and performance assessment in humans. In particular, the use of non-contact videophotoplethysmography (vPPG) has been recently demonstrated as a feasible way to extract cardiovascular information. Nevertheless, proper validation of vPPG-derived heartbeat dynamics is still missing.

Objective: We aim to an in-depth validation of time-varying, linear and nonlinear/complex dynamics of the pulse rate variability extracted from vPPG.

Methods: We apply inhomogeneous pointprocess nonlinear models to assess instantaneous measures defined in the time, frequency, and bispectral domains as estimated through vPPG and standard ECG. Instantaneous complexity measures, such as the instantaneous Lyapunov exponents and the recently defined inhomogeneous point-process approximate and sample entropy, were estimated as well. Video recordings were processed using our recently proposed method based on zerophase principal component analysis. Experimental data were gathered from 60 young healthy subjects (age: 24±3 years) undergoing postural changes (rest-to-stand maneuver).

Results: Group averaged results show that there is an overall agreement between linear and nonlinear/complexity indices computed from ECG and vPPG during resting state conditions. However, important differences are found, particularly in the bispectral and complexity domains, in recordings where the subjects has been instructed to stand up.

Conclusions: Although significant differences exist between cardiovascular estimates from vPPG and ECG, it is very promising that instantaneous sympathovagal changes, as well as time-varying complex dynamics, were correctly identified, especially during resting state. In addition to a further improvement of the video signal quality, more research is advocated towards a more precise estimation of cardiovascular dynamics by a comprehensive nonlinear/complex paradigm specifically tailored to the non-contact quantification.
MicroRNA-411 Inhibits Cervical Cancer Progression by Directly Targeting STAT3
Authors: Shan Dan , Shang Yumin , Hu Tongxiu
Published: May 2018

Cervical cancer is the third most common gynecological cancer and the fourth leading cause of cancer-related deaths in women around the world. Substantial evidence has demonstrated that microRNA (miRNA) expression is disordered in many malignant tumors. The dysregulation of miRNAs has been suggested to be involved in the tumorigenesis and tumor development of cervical cancer. Therefore, identification of miRNAs and their biological roles and targets involved in tumor pathology would provide valuable insight into the diagnosis and treatment of patients with cervical cancer. MicroRNA-411 (miR-411) has been reported to play an important role in several types of human cancer. However, the expression level, role, and underlying molecular mechanisms of miR-411 in cervical cancer remain unclear. Therefore, the objectives of this study were to investigate the expression pattern and clinical significance of miR-411 in cervical cancer and to evaluate its role and underlying mechanisms in this disease. In this study, we confirmed that the expression of miR-411 was significantly downregulated in both cervical cancer tissues and cell lines. Low expression of miR-411 was associated with tumor size, FIGO stage, lymph node metastasis, and distant metastasis. Additionally, miR-411 overexpression inhibited cell proliferation and invasion in cervical cancer. Furthermore, signal transducer and activator of transcription 3 (STAT3) was identified as a direct target of miR-411 in this disease. In clinical samples, miR-411 expression levels were inversely correlated with STAT3, which was significantly upregulated in cervical cancer. Restored STAT3 expression abolished the tumor-suppressing effects of miR-411 overexpression on the proliferation and invasion of cervical cancer cells. In conclusion, our data demonstrated that miR-411 inhibited cervical cancer progression by directly targeting STAT3 and may represent a novel potential therapeutic target and prognostic marker for patients with this disease.
AGEING MODELS AND ACCELERATED AGEING TESTS OF GLASS FIBER REINFORCED CONCRETE
Authors: MOCEIKIS Rimvydas , KIČAITĖ Asta , SKRIPKIŪNAS Gintautas , KORJAKINS Aleksandrs
Published: May 2018

Glass fiber reinforced concrete (GRC) is used for 40 years to create world’s most stunning and complex architectural elements due to its high mechanical properties, particularly flexural strength. Yet it is very important to note that any type of glass fibers in the concrete matrix are undergoing complex ageing processes, resulting to significant decrease of initial mechanical characteristics of this composite material under natural weathering conditions. Aspects of GRC durability are mainly dependent from the properties of fibers and interaction between them and concrete matrix. In this article, long term strength retention of this composite material is discussed, existing experimental data of weathering tests presented, and main corrosion mechanisms explained. Lack of knowledge about freeze- thaw resistance of glass fiber reinforced concrete is addressed. Finally, latest attempts of GRC durability improvement are reviewed, such as adding micro fillers, polymers to the concrete matrix and enhancing surface of fibers in Nano scale.
Princípios fundamentais para o ensino e a aprendizagem do inglês como língua global
Authors: Dos Anjos Flavius Almeida
Published: May 2018

Este artigo propõe refletir sobre princípios fundamentais para o ensino e a aprendizagem do inglês como língua global. Busca, na perspectiva da era pós-colonial e à luz da Linguística Aplicada, articular o dialogo com autores (BOAVENTURA DE SOUSA SANTOS, 2009; PENNYCOOK, 2000; KUMARAVADIVELU, 2012; RAJAGOPALAN, 2003, 2009 e GROSFOGUEL, 2009) cujas ideias convergem para a descolonização do conhecimento. Ancorado na Pedagogia Crítica e levando em consideração o status global da língua inglesa, este trabalho pavimenta o caminho para a discussão sobre problemas que enfrentam a educação básica e superior, quando ainda relegam a um segundo plano o ensino da língua inglesa, a mercê de políticas linguísticas frágeis. A discussão é ampliada para, por fim, trazer em seu bojo proposta de descolonização da língua inglesa, adotando pedagogias críticas que possibilitem emancipar os aprendizes para que possam usar esse idioma global com autonomia e livres das amarras das ideologias colonialistas que limitam o pensamento e inferiorizam povos e culturas, o que só poderá acontecer a partir de princípios que orientem docentes à consolidação de aprendizagens significativas.
Palavras metafóricas monoicas: tópico e veículo implícitos
Authors: Nascimento Neto Reginaldo
Published: May 2018

Este artigo pretende discutir brevemente se o processamento cognitivo da metáfora, por meio de um mecanismo de associação, inferências, comparação e identificação criativa do pensamento a um gabarito mental, pode ser responsável pelo uso e menção de palavras metafóricas monóicas amalgamando tópico e veículo de forma unirreme e implícita, isto é, sem externá-los. Para tanto, parte-se de um vislumbre histórico sobre os conceitos de metáfora concebidos por Aristóteles(1996), Richards(1936), Black (1993), Searle(1993) e Lakoff & Johnson (2002) para se demonstrar que os elementos essenciais da metáfora, diversamente reconhecidos dependendo do autor como tópico e veículo, Frame e foco, domínio alvo e domínio fonte, S é P e S é R, ou tipo e antítipo, podem ocorrer na esfera do pensamento e produzir palavras metafóricas, percebidas ou não como tal, que se manifestam de forma monóica ao invés de na sentença como advoga o interacionismo. Para tanto, apresentam-se algumas palavras cuja etimologia embutem tópico e veículo. As conclusões a que se chega é que no processo de onomasiologia, como revela o estudo da etimologia, em muitos casos, o uso da metáfora funde em uma só palavra o tópico e o veículo.