bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Stable Water Isotopes to Analyze Spatiotemporal Variability and Hydrometeorological Forcing in Mountain Valley Wetlands
Authors: Hathaway Julia M. , Petrone Richard M. , Westbrook Cherie J. , Rooney Rebecca C. , Langs Lindsey E.
Published: June 2022

Wetlands in Montane and Subalpine Subregions are increasingly recognized as important hydrologic features that support ecosystem function. However, it is currently not clear how climate trends will impact wetland hydrological processes (e.g., evaporative fluxes) across spatiotemporal scales. Therefore, identifying the factors that influence wetland hydrologic response to climate change is an important step in understanding the sensitivity of these ecosystems to environmental change. We used stable water isotopes of hydrogen and oxygen (δ2H and δ18O), coupled with climate data, to determine the spatiotemporal variability in isotopic signatures of wetland source waters and understand the influence of evaporative fluxes on wetlands in the Kananaskis Valley. Our results show that the primary runoff generation mechanism changes throughout the growing season resulting in considerable mixing in wetland surface waters. We found that evaporative fluxes increased with decreasing elevation and that isotopic values became further removed from meteoric water lines during the late peak- and into the post-growing seasons. These findings suggest that a change in the water balance in favor of enhanced evaporation (due to a warmer and longer summer season than present) will not only lead to greater water loss from the wetlands themselves but may also reduce the water inputs from their catchments.
Great burdock: useful properties and its use for food purposes
Authors:   Military Academy of Air and Space Defense named after Marshal of the Soviet Union G.K. Zhukov, Rodionova A.E.
Published: June 2022

The article discusses the use of the ruderal weed — great burdock in medicine and cooking. Its chemical composition, nutritional value, and recipes for burdock dishes, which allow considering this plant as a functional additive, are examined.
Problematic aspects of the classification of bakery products for customs purposes
Authors:   Russian Customs Academy, Krishtafovich D.V. , Skupova M.D. ,   Russian Customs Academy
Published: June 2022

This article discusses the problematic aspects of the classification of bakery products in foreign trade activities based on the analysis of judicial practice materials and suggests ways to solve them. Disputable points arise between the participants in foreign economic activity and the customs authorities due to the incorrectly chosen classification code of the goods in accordance with the Commodity Nomenclature of Foreign Economic Activity of the Eurasian Economic Union.
Assortment of the subcategory “Dried fruits, vegetables and mushrooms” and directions of the assortment policy of retail trade organizations for this subcategory
Authors:   Russian Academy of National Economy and Public Administration under the President of the Russian Federation, Nikolaeva M.A. , Lokshin A.D. ,   Russian Academy of National Economy and Public Administration under the President of the Russian Federation
Published: June 2022

The article presents the results of a survey and analysis of the real trade assortment of dried fruits and vegetables, as well as the main directions of the assortment policy of chain stores selling goods of this subcategory. It has been established that the greatest completeness, depth and stability of the assortment were noted in Ashan and Globus stores. The coefficient of rationality of their assortment is characterized by a moderate value. The lower values of these indicators and the lowest rationality were observed in the assortment of this subcategory in the Magnit store. The main directions of their assortment policy are the deepening, updating and stabilization of the assortment, which allows them to form a moderately rational assortment of this subcategory (Ashan and Globus) or close to it (Magnit).
Analysis of the assortment and assortment policy for pastille and marmalade products
Authors:   Russian Academy of National Economy and Public Administration under the President of the Russian Federation, Nikolaeva M.A. , Gevorgyan A.A. ,   Russian Academy of National Economy and Public Administration under the President of the Russian Federation
Published: June 2022

The purpose of this article is to survey the trade assortment for pastille and marmalade products sold in retail trade enterprises in Moscow, as well as to analyze the indicators of the assortment and assortment policy of trade organizations. The article presents the results of a survey of the assortment of the subcategory “Pastille and marmalade products”, conducted in three chain stores in Moscow. It has been established that the expanded assortment of these products is characterized by great depth, moderate stability and low novelty. The degree of rationality of the assortment in different stores is not the same.
Meat storage under acoustic freezing conditions and assessment of its biotoxicity (part 2)
Authors:   Trading House “Biosnabsbyt” company, Sidorenko Yu.I. , Balabolin D.N. ,   “Acoustic freezing” company, Simakov Yu.G. ,   Moscow State University of Technology and Management named after K.G. Razumovsky, Livinskaya S.A. ,   Federal Center for Monitoring Student Nutrition of the Ministry of Education of the Russian Federation, Yuditskaya I.M. ,   Moscow State Budgetary Educational Institution “School No. 2083”, Plechev E.A. ,   Moscow State Budgetary Educational Institution “School No. 2083”, Sidorenko A.A. ,   Moscow State Budgetary Educational Institution “School No. 2083”, Trotsyuk A.I. ,   Moscow State Budgetary Educational Institution “School No. 2083”, Shurupov D.A. ,   Moscow State Budgetary Educational Institution “School No. 2083”
Published: June 2022

The necessity of developing new technologies for refrigerated storage, providing improved quality and safety of meat products, is shown. A critical analysis of cold storage methods has been carried out and the choice of the acoustic freezing method has been substantiated. As a result of the joint work of the students of school No. 2083, “Acoustic Freezing” company and the Institute of Biotechnology and Fisheries, Moscow State University of Technology and Management named after K.G. Razumovsky, studies were carried out to establish the degree of toxicity of pork subjected to refrigeration storage under conditions of shock and acoustic freezing. Histological studies of fresh meat and meat after acoustic and shock freezing have shown that shock freezing leads to a violation of the structure of striated muscles due to the formation of large ice crystals during freezing. The method of fractal analysis of proteins in fresh meat and meat after acoustic freezing showed that the ice crystallization in muscle tissue leads to the formation of different types of fractals. Fractal analysis can be used to select physical factors when improving the technology of acoustic freezing. Toxicological studies were carried out on juvenile clawed frogs Xenopus laevis fed with chironomid larvae, California worms Eisenia fetida (control), fresh meat and meat after acoustic freezing. Studies have shown that there are no significant deviations in the cytological parameters of red blood in frogs eating natural food (worms) and meat after acoustic freezing. Meat after shock freezing is eaten poorly by frogs, which indicates a significant loss of its quality compared to fresh meat. Comparative studies on the effects of feeding fresh meat and meat after acoustic freezing, carried out on the blood of laboratory fish Danio rerio, demonstrated that fresh meat and meat after acoustic freezing do not cause harmful effects on the red blood of fish. The work was carried out within the framework of the program for the introduction of project methods of school education in the secondary school of the Moscow State Budgetary Educational Institution “School No. 2083”.
Influence of biologically active additives on dynamics of live weight and growth of muscles in poultry
Authors:   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow, Semak A. E. , Prosekova E. A. ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow, Savchuk S. V. ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow, Panina E. V. ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow, Cherepanova N. G. ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow
Published: June 2022

There is a lack of understanding of the effects of feed additives on the organs of different body systems of productive animals. The issues of the impact of biologically active additives to feed, their compatibility, are very relevant, and with an increase in the number and range of additives, the importance and criticality of the issue of their interaction increases. Some results of determining the dynamics of the gain in the weight of individual muscles of broiler chickens and Japanese quails have been received biologically active additives such as Rovimix Hy-D (25(OH) D₃, calcidiol, the main circulating metabolite of vitamin D) and the enzyme complex “Natuzim” have been presented in the paper. Indicators of the growth rate of the live weight of the poultry and the weight of the thoracic and thigh muscles were obtained for the growing periods. In the experiment on broilers, it was revealed that the addition of calcidiol with constant administration in the first two weeks of rearing had a rather negative effect on the growth of muscle weight and live weight. At the same time, the enzyme additive contributed to the increase in indicators at the beginning of rearing. In the second half of rearing on the contrary the enzyme additive had the negative effect on growth indicators, and calcidiol, especially in combination with mineral additive noticeably stimulates the growth of muscle weight and body weight in general. Japanese quails received the additive Rovimix Hy-D in three different dosages, because to date the additive has not been tested on quails. The data obtained confirm, from the one hand, the justification of the use of the feed additive Rovimix Hy-D as the additional source of vitamin D in broiler and quail feed, as well as the absolute need to take into account t
Morphological and functional traits and main disadvantages of the udder in cows of Black-and-White breed
Authors:   Federal State Budgetary Educational Institution of Higher Education “Penza State Agrarian University”, Russia, Penza, Shishkina T. V. , Nikishova N. V. ,   Federal State Budgetary Educational Institution of Higher Education “Penza State Agrarian University”, Russia, Penza
Published: June 2022

The object of research was the first-calf cows of Black-and-White breed. The groups were formed taking into account the part of blood of Holstein breed. The 1st group included animals with the part of blood than 50 % (an average of 37 % in the group), the 2nd with the part of blood of 50 % and the 3rd more than 50 % (an average of 63 % in the group). An increase in the part of blood in animals in the farm to 63 % had a positive effect on changing the shape of the udder. Thus, in the group of low the part of blood animals there were 78,2 % of cows with a cup-shaped shape and 21,8 % with a rounded one. Among half-blood cows with the cup-shaped udder accounted for 92,2 %, and with the rounded one it was 7,8 %, among the high part of blood it was 94,8 and 5,2 %%, respectively. In terms of udder length and depth measurements, cows with the high part of blood outperformed cows with the low part of blood by 2,5 cm (р < 0,01) and 2,1 cm (р < 0,01), respectively. In terms of udder decline, the difference between these groups of animals was 5,7 abs.% (р < 0,01) in favor of animals with the higher proportion of Holstein breed blood. First-calf cows with half part of blood and the high part of blood of Holstein breed were ahead of their herd mates with the low part of blood in terms of the rate of milk speed out the difference was 0,3 kg/min (р < 0,05) and 0,4 kg/min (р < 0,001), respectively. The most common udder defect (10 %)was narrow rear teats, while in the group with the high part of blood cows its occurrence was the lowest 6,7 %. The sum of the frequencies of udder defects in cows with the high part of blood was 16,7 % versus 23,3 % in the other two groups. We recommend to use purebred Holstein sires for mating with low-blood heifers and cows, and using sires with the part of blood of Holstein breed of 62 to 75 % or breeding “inter se” on heifers and cows with the higher proportion of blood of Holstein breed.
Actual problems of land management and cadastre in the Republic of Dagestan and ways of solution
Authors:   Dagestan State Technical University, Makhachkala, Babakhanov S.G. , Kurbanova Z.A. ,   Dagestan State Technical University, Makhachkala, Shabanova S.G. ,   Dagestan State Technical University, Makhachkala
Published: June 2022

This paper presents the current state of agricultural land use and suggests measures to improve land relations in the region.
Selenium-containing drug together with the feed additive Benut in the rations of steers
Authors:   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agricultural University”, Russia, Volgograd, Kulik D. K. , Varakin A. T. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agricultural University”, Russia, Volgograd
Published: June 2022

Currently, there is great interest in the use of selenium drugs in animal husbandry. Chickpea is high-containing in selenium and protein. The feed additive Benut, made on the basis of chickpea, has a high content of selenium. At the same time, its active interaction with proteins was revealed. The purpose of the work was to increase the meat productivity and quality of beef of steers when using the selenium-containing drug DAFS-25 in rations together with the feed additive Benut. In order to conduct the experiment, according to the principle of analogues 3 groups of Aberdeen-Angus steers were formed at the age of 9 months for 15 heads in each group. The duration of the experiment was 172 days including the main period 150 days. In the main period, the steers of the 1st control group received the main ration (MR), the 2nd experimental group received MR + DAFS-25 (1,6 mg/kg of concentrates) and the 3rd experimental group received MR + 0,5 kg/head/day of the feed additive Benut (instead of an equivalent amount of concentrates) + DAFS-25 to ensure the content of selenium as in the ration of animals of the 2nd experimental group. The beef productivity of fattened steers of Aberdeen-Angus breed was studied and also indicators of blood composition, digestibility and assimilation of feed nutrients, beef quality and efficiency of its production, when used in rations of the drug DAFS-25 separately and in combination with the feed additive Benut. Profit from the sale of beef in the 2nd experimental group was received by 84,4 rubles more and in the 3rd experimental group by 574,8 rubles more than in the 1st control group. In the 2nd and 3rd experimental groups the profitability level was 1,2 and 13,2 % higher than in the 1st control group (27,3 %).
Prerequisites for the development of regional animal husbandry
Authors:   Federal State Budgetary Educational Institution of Higher Education “South Ural State Agrarian University”, Russia, Chelyabinsk region, Troitsk, Krasnoperova E. A. , Karmatskikh Yu. A. ,   Federal State Budgetary Educational Institution of Higher Education “Kurgan State Agricultural Academy named after T. S. Maltsev”, Russia, Kurgan region, Lesnikovo, Kostomakhin N. M. ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow
Published: June 2022

The Chelyabinsk region is a major industrial and agricultural center of the country. It has over 3,5 million people and ranks 3rd out of eight regions of the Urals and 9th in the Russian Federation. The purpose of the work is to consider the prerequisites for the development of various branches of animal husbandry in the Chelyabinsk region. The authors consider the problem from different perspectives such as natural and climatic conditions, market demand for food, evaluation of raw materials and final products from the technologies used. It is determined that the development of livestock industries in the region is determined by both natural and economic and social problems of agriculture. For example, currently the leading breed of the dairy industry in the region is Black-and-White breed. Without belittling the merits of this breed, we believe the possible spread of other breeds, it all depends on the preferences of livestock owners, because many breeds have unique productive traits. The development of sheep breeding in the region is very important, because the population of the region is multinational in its composition. It is also home to about half a million residents, in whose consumption culture horsemeat occupies an important place. In drove breeding of horses they are able to graze on natural pastures from May to October. Horse breeding can produce not only horse meat, but also koumiss, a fermented milk product obtained from mare’s milk. The demand for horse meat, koumiss, as well as mutton is high in this region. The authors come to the conclusion that the further increase in livestock production is linked to the prospects of development not of large agricultural holdings, but of peasant farms and personal subsidiary farms. In solving these problems, a huge organizational and economic role belongs to regional and local authorities.
Management accounting: monitoring actions when designing the starting of production
Authors:   Izhevsk State Agricultural Academy, Ostaev. G. Ya. , Zlobina O. O. ,   Izhevsk State Agricultural Academy, Alborov G. R. ,   Izhevsk State Agricultural Academy, Kotlyachkov O. V. ,   Izhevsk State Agricultural Academy, Dzhikiya M. K. ,   Federal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”, Moscow
Published: June 2022

The article deals with the issues of accounting and management information of the current economic state of organization management, which is the most important tool. The need for the formation of accounting and management information, first of all, is necessary for administrative personnel (managers) to clearly form a picture of the development of the organization in the future. The study reveals the key points of accounting and management actions and monitoring of business processes for designing the launch of cheese and butter production. It is concluded that, despite the complexity and specifics of management accounting for designing the launch of cheese and butter production, organizations must constantly collect and process accounting and management, including accounting and analytical information for an objective assessment of all risks and opportunities for promoting business on domestic and foreign market.
Formation of accounting information about fixed assets in accounting in accordance with FSBU 6/2020 “Fixed Assets”: assessment, revaluation, procedure for calculating depreciation, impairment
Authors:   Federal State Budgetary Educational Institution of Higher Education «Stavropol State Agrarian University», Sytnik O.E. , Kulish N.V. ,   Federal State Budgetary Educational Institution of Higher Education «Stavropol State Agrarian University», Khoruzhy V.I. ,   Financial University under the Government of the Russian Federation
Published: June 2022

The article presents the procedure for generating information about fixed assets in accounting, considering the requirements of FSBU 6/2020 “Fixed Assets”. Attention is paid to the main changes introduced by the specified standard in terms of the assessment and revaluation of fixed assets, the accrual of depreciation charges on them and their depreciation. The composition of the information disclosed in the accounting policy for accounting purposes in terms of the issues under consideration has been substantiated.
Peculiarities of assessment and recognition in accounting of certain types of reserves
Authors:   Izhevsk State Agricultural Academy, Selezneva I. P. Selezneva I. P. , Selezneva I. A. ,   Izhevsk State Agricultural Academy, Shlyapnikova E. A. ,   Izhevsk State Agricultural Academy, Mosunova E. L. ,   Izhevsk State Agricultural Academy, Dzhikiya K. A. ,   ederal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”, Moscow
Published: June 2022

The article is devoted to the disclosure of issues and problems of assessment, identification and recognition of stocks in the accounting system of organizations, as well as determining the directions for their improvement. The organizational and methodological aspects that determine the concept and composition of reserves as the most important objects of accounting are considered. The criteria for their recognition in the accounting system are considered, the problems and options for the formation of their actual cost in the conditions of the existence of various sources (channels) of their receipt are disclosed. Variants of reflection of separate operations of receipt of stocks in accounting of the organization are offered.
Innovations and possible problems in the application of FSBU 27/2021
Authors:   Vyatka State University, Kirov, Zonova A. V. , Kholkin A. V. ,   Vyatka State University, Kirov
Published: June 2022

The article discusses innovations in the documents that form the regulatory framework of accounting in terms of the regulation of the process of documentation and development of document flow. The results of comparing the provisions of FAS 27/2021 with other regulatory acts, including acts that have become invalid, are presented. Possible problems of the application of FAS 27/2021 in the practical activities of accounting services of economic entities have been identified.
Features of recognition and evaluation of environmental remedetion obligations in accordance with IFRS and US GAAP
Authors:   Financial University under the Government of the Russian Federation, Moscow, Grishkina S. N. , Trushina A. A. ,   Financial University under the Government of the Russian Federation, Moscow
Published: June 2022

The main features of the formation of the amount of environmental remediation obligations are discussed in the article. The relevance of this issue requires a reasonable and appropriate assessment of these obligations. The article analyzes the similarities and differences in the interpretation of the main features of accounting for environmental obligations in accordance with IFRS and US GAAP.
COOKIES BAYAM DAN TEPUNG SORGUM KAYA AKAN ZAT BESI SEBAGAI MAKANAN TAMBAHAN UNTUK IBU HAMIL DENGAN ANEMIA
Authors: Rahmat Mamat , Priawantiputri Witri , Pusparini Pusparini
Published: June 2022

Anemia pada Ibu Hamil merupakan masalah yang serius di Indonesia, prevalensi anemia pada ibu hamil tahun 2013 sebesar 31,8 % dan pada tahun 2018 meningkat menjadi 48,0 %.  Dampak Anemia pada Ibu Hamil berbahaya bagi Ibu dan juga janin yang dikandung.   Cookies bayam sorgum merupakan inovasi makanan tambahan untuk Ibu Hamil yang mengandung zat besi.  Penelitian ini bertujuan untuk membuat produk pangan lokal yang kaya akan zat besi sebagai makanan tambahan bagi Ibu Hamil dengan Anemia.  Pada penelitian ini dibuat tiga formula imbangan bayam hijau berbanding tepung sorgum, formula 1 (10:90%), formula 2 (20%:80%), formula 3 (30%:70%).  Uji hedonik dilakukan pada 30 subjek panelis Ibu Hamil untuk melihat tingkat kesukaan pada aspek warna, aroma, rasa dan tekstur.  Kandungan zat gizi makro, serat pangan dan zat besi diukur dengan metode Spektrofotometri Serapan Atom (SSA).  Ada pengaruh imbangan bayam dan tepung sorgum terhadap warna, aroma, dan rasa cookies bayam sorgum (p=0.000). Cookies formula 1 merupakan cookies dengan tingkat kesukaan terbaik dan memenuhi syarat SNI dari Cookies.  Kandungan zat gizi cookies bayam sorgum formula 1 per 100 g adalah energi 459.6 kkal, karbohidrat 70.53 g,  kadar protein 10.3 g, kadar lemak 17.07 g, kadar serat pangan 10.33, dan kadar zat besi 2.51 mg.  Cookies bayam sorgum dapat menjadi alternatif makanan tambahan bagi ibu hamil.
POLA PENGGUNAAN OBAT ANTIHIPERTENSI PADA POPULASI GERIATRI DI RUMAH SAKIT UMUM DAERAH KABUPATEN MAJENE
Authors: Mira Atjo Neng , Marhaen Hardjo , Vita Soraya Gita
Published: June 2022

Hipertensi ialah permasalahan kesehatan utama di Indonesia dan juga di berbagai negara di dunia. Berdasarkan penelitian epidemiologi, diperoleh bahwa seiring bertambahnya usia, tekanan darah juga meningkat. Hipertensi menjadi masalah pada geriatri sebab menjadi penyebab utama penyakit jantung koroner. Tujuan: Untuk menilai pola penggunaan obat antihipertensi pada populasi geriatri dan kepatuhan pengobatan hipertensi terhadap pedoman pengobatan hipertensi JNC-8 dalam populasi geriatri. Metode: Ini adalah penelitian observasional cross-sectional menggunakan data retrospektif yang terdiri dari rekam medis pasien hipertensi rawat jalan di Rumah Sakit Umum Daerah di Kabupaten Majene, Indonesia. Sampel yang dianalisis adalah pasien geriatri (≥ 60 tahun) dengan hipertensi. Penelitian ini dilakukan antara Juli dan Oktober 2019. Hasil: Dari 196 pasien, 80 (40,81%) adalah laki-laki dan 116 (59,18%) adalah perempuan. Sebagian besar resep diberikan sebagai penggunaan terapi tunggal (72,5%) dan sisanya sebagai penggunaan terapi ganda sebagian besar terdiri dari kombinasi dua obat (27,5%). Diuretik dengan ACEi adalah kombinasi yang paling banyak digunakan (14,3%), diikuti oleh CCB dengan ACEI (7,7%) dan diuretik hemat Kalium (3,1%), CCB + ARB terakhir (2,6%). Persentase untuk pasien hipertensi stadium 1 adalah 77% dan 15,3% untuk stadium 2. Kesimpulan: Pengobatan hipertensi pada pasien geriatri di Rumah Sakit Umum Kabupaten Majene tidak sepenuhnya sesuai dengan pedoman JNC-8 saat ini.
O estigma do traficante: guerra às drogas, a deterioração da identidade do criminalizado / The stigma of the trafficker: war on drugs, the deterioration of the identity of the criminalized
Authors: Kuhn Marcelo Schenkman , Fortes Thaís Cruz Silva
Published: June 2022

Trata-se de artigo que pretende explorar o contexto histórico da Guerra às Drogas, suas consequências diretas para com os indivíduos criminalizados que passam pelo processo de estigmatização. Ainda assim, busca demonstrar como este processo deteriora a identidade do indivíduo.
PERFORMED FACTORS IN THE REHABILITATION OF CARDIAC PATIENTS ON AN OUTPATIENT BASIS
Authors: Tokarenko О. I. , Kovaleva O. V. , Kovaleva A. A. , Tokarenko O. O.
Published: June 2022

In older people, adequate pharmacological tactics when using modern antihypertensive drugs and their combinations, which provide maximum cardiovascular protection, can increase the duration and improve the quality of life, significantly reduce the likelihood of complications. An increase in the tone of the sympathetic nervous system leads to biliary dyskinesia by hypokinetic type, an increase in blood pressure.

The aim is to optimize the treatment of patients with high blood pressure, rhythm disturbances, to analyze the possibility of using Poltava's Bischofite mineral compound, dietary magnesium-mineral supplements Bisheffect, in the complex treatment of hypertension for internal use.

Matherials and methods. 68 patients with arterial hypertension with concomitant hepatobiliary pathology, which was confirmed by clinical and instrumental research methods, were under observation. The patients’ mean age was 47.9 ± 2.9 years. The analysis of heart rate variability was carried out during a test with physical activity on a bicycle ergometer with “Cardiolab+” equipment (“XAI-Medica, Kharkiv, Ukraine). In addition, daily monitoring of blood pressure was carried out using the ABPM-04 - Meditech apparatus.

Result. By the end of the first week of treatment, most patients (82.34%) noted a significant improvement in well-being. During bicycle ergometry, autonomic nervous system stabilisation, blood pressure normalisation, a decrease in the number of extrasystoles, the sleep and the stool normalisation were recorded. The reason for the failure of standard antiarrhythmic therapy in this group of patients was determined based on the studies. Such a problem was observed due to dysfunction of the autonomic nervous system, which is an integral companion of the pathology of the gastrointestinal tract. This concept involves expanding the diagnostic search and stimulates the search for new ways of rhythm disturbances treatment in the pathology of the gastrointestinal tract. Also, the indices of blood pressure variability have decreased. Average 24h blood pressure in patients on the 10th day of treatment decreased by an average of 25-35 mm Hg, and there was a decrease in cranialgia attacks and autonomic disorders. An increase in the blood ejection fraction by 34%, a heart's stroke volume by 19%, and a normalisation of the minute volume (p˂0.05) were revealed, which confirms the positive effect of bischofite-therapy in the complex treatment of cardiac pathology.

Conclusions. Treatment with standard LEIT-therapy, use of dietary magnesium-mineral Bisheffect supplements resulted in the autonomic nervous system stabilisation, blood pressure normalisation, a decrease in the number of extrasystoles, the sleep and the stool normalisation, increased exercise tolerance.
Radiation diagnostics of the state of ventilation and pulmonary circulation in patients with COPD
Authors: Sementsov O. S. , Stepanenko S. V.
Published: June 2022

COPD is one of the most common human diseases. WHO experts predict an increase in economic damage from COPD by 2020 and claim that they will rank first among respiratory diseases and third among all causes of death. In Ukraine, about 3 million people, or at least 7% of the population, suffer from COPD. The purpose of the study is to analyze the available literature sources to establish the current state of the problem of radiological diagnosis of COPD, to identify problematic issues. Based on the analysis of literature data, it can be concluded that for a comprehensive examination of patients with COPD or suspected COPD, and assessment of external respiration - clinical examination and spirometry, especially in the early stages of the disease - is not enough. It is believed that in the initial stages of COPD, when spirometry and clinical data do not reveal abnormalities, radiological diagnosis is more sensitive than functional tests. Among the modern methods of radiological diagnosis of lung diseases - the method of CT today is the most sensitive and specific method of detecting pathological changes in the lung parenchyma and respiratory tract, it is available and widely used in everyday practice. Also a promising area is the use of functional CT (inspiratory-expiratory CT) - which should improve the assessment of respiratory function, including early detection of patients with COPD, which will promote the in time start of specific treatment, reduce episodes of exacerbations during the disease, assess the dynamics of the pathological process and the effectiveness of treatment, as well as improving the prognosis of work and life expectancy of patients. However, given the lack of unifying works on the study of this method, further studies of the capabilities of computed tomography in the diagnosis of signs of dysfunction of external respiration in patients with COPD are required. First of all, further research is required on the distribution of air trap zones, especially in patients with emphysema, it is desirable that these future studies are not based only on the principle of visual assessment in the form of exclusion / confirmation of air trap zones.
ANTIBACTERIAL THERAPY IN INFECTED FORMS OF NECROTIC PANCREATITIS
Authors: Goldovskiy B. M. , Medvedev V. P. , Filimonova I. V. , Miheev Yu. O. , Lelyuk D. V. , Paketa A. I. , Litvinenko V. V.
Published: June 2022

Summary: Evaluation of the effectiveness of antibacterial therapy at different stages of necrotic pancreatitis (NP) is the most important area of ​​scientific and practical research on the course of necrotic pancreatitis and the development of sepsis. The work is based on the results of a comprehensive examination and treatment of 54 patients with necrotic pancreatitis in the intensive care unit of city Hospital № 3, Zaporizhia in 2017-2019 pp.

Objective: Optimize the use of antibacterial therapy in the complex treatment of infected forms of NP depending on the microbial spectrum of infection, the course of the disease and the development of sepsis.

Material and methods of research. The study included 54 patients with infected forms of NP who were treated in the Department of Anesthesiology and Intensive Care of the 3rd City Hospital. Research results and their discussion. Thus, the analysis of antibiotic sensitivity showed that high activity against pathogens, based on the perception of the main pathogens characteristic of infected forms of NP, is observed in meropenem, taigecycline and tobramycin. When studying the species composition of microorganisms, it was found that the NP is dominated by gram-negative flora: Pseudomonas aeruginosa - 26.5%, Acinetobacter spp. - 21.2%, family Enterobacteriaceae: Klebsiella pneumoniae - 10.2% and Escherichia coli - 15.6%. Resistant strains of Ps were found in 22% of patients. Aeruginosa. The use of detoxification therapy with the inclusion of extracorporeal detoxification methods (discrete plasmapheresis) in combination with two-component antibacterial therapy (meropenem + linezolid) led to a positive trend in the course of the disease.

Conclusions. Analyzing the course of the disease in patients with infected NP and its complications on the basis of constant monitoring of bacterial flora with optimal antibacterial therapy, prevention of nosocomial infection and modern strategy of surgical interventions, especially minimally invasive, noted a positive trend in the course of sepsis and sepsis.
Diagnostic capabilities of optical coherence tomography and optical coherence tomography angiography in the diagnosis of primary open-angle glaucoma
Authors: Lutsenko N. S. , Nedilka T. V.
Published: June 2022

Abstract. to assess the features of the retinal nerve fiber layer (RNFL), ganglion complex (GC) and the microcirculatory bed of the retina in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).

Materials and methods: The study involved 20 people (11 females, 9 males). Patients were divided into 2 groups. The first group included 10 clinically healthy individuals, the second group - 10 patients with POAG. All patients underwent standard ophthalmic examination, OCT / OCTA examination of the RNFL, GC and retinal microcirculatory bed.

Results: The study identified the most sensitive indicators to the progression of the glaucoma process. It was found that the RNFL thickness and the density of the retinal vascular progressively decrease with the development of glaucoma opticopathy. Compared with the group of healthy individuals in patients with POAG, the RNFL thickness in the lower temporal sector of the peripapillary zone was reduced by 44.04% (p <0,01). Compared with healthy individuals, the density of the superficial vascular plexus decreased by 16.3%, deep - by 12.5% ​​(p <0,01). The perimeter of the foveolar avascular zone in patients with glaucoma increased by 31.01%, the area of ​​the foveolar avascular zone increased 1.6 times (p <0.01).

Conclusions: OCT and OCTA are effective methods for assessing the state of GC, RNFL and microcirculatory bed of the retina, which allow for non-invasive monitoring and evaluation of these indicators in patients with POAG.
The use of procalcitonin in patients with pyogenic liver abscesses
Authors: Novak V. V.
Published: June 2022

The results of treatment of 79 patients with pyogenic liver abscesses (AP) were analyzed. Sepsis was diagnosed in 10 (16.1%) patients. Procalcitonin (PCT) levels were used to diagnose sepsis. The duration of antibacterial therapy (ABT) was based on the determination of PCT and the patient's clinical condition. The decision to prescribe or abstain from ABT should be reviewed within the next 6-24 hours based on the patient's clinical condition and PCT level. These values ​​should also be taken into account in the decision-making process regarding the duration of ABT, as well as the clinical course of the disease. There were no fatalities in the treatment of AP.

Purpose of the study. To determine the diagnostic and prognostic significance of procalcitonin in patients with pyogenic liver abscesses.

Materials and methods. The results of treatment of 79 patients with pyogenic liver abscesses were analyzed. The mean age of patients was 48.4 ± 4.7 years, with men predominating (62.9%). The inclusion criterion was the presence of pyogenic liver abscesses, the exclusion criteria were cholangiogenic and specific abscesses. The main group consisted of 44 patients who received comprehensive conservative therapy, taking into account antibacterial treatment, the duration of which was determined by determining the level of PСT. Patients in the control group (35 patients) did not differ from the main in age, sex, comorbidities, severity of the disease and the results of microbiological examination, but received conventional ABT.

Results.  Carrying out adequate combined antibiotic therapy in patients with AP by determining PKT, along with surgery, reduced the recovery time of patients: 2-3 days normalization of body temperature (t = 5.66176; P <0.000001) and leukocyte formula (t = 8,56860; P <0,000001) patients of the main group compared with control patients

Conclusion. Conducting ABT by determining the level of PСT contributed to a probable reduction in the length of stay in the hospital for 3 days (t = 3.95561; P = 0.000116).
EFFICIENCY OF PAIN SYNDROME TREATMENT IN PATIENTS WITH MUSCULOSKELETAL PATHOLOGY IN COMPLEX USE OF SHOCK-WAVE AND HIGH TONE POWER THERAPY
Authors: Alypova O. E. , Dotsenko O. M. , Dotsenko S. Ya.
Published: June 2022

Purpose of the study. Pain is the main complaint of patients with musculoskeletal pathology, the treatment of which by pharmacological methods has significant side effects. Therefore, non-drug treatment, especially physiotherapy, is increasingly being considered as a first-line treatment option. We evaluated the effectiveness of treatment of pain syndrome in complex use of Shock Wave (SW) and High-Tone Power (HiToP) physiotherapy in patients with musculoskeletal pathology.

Methods. We examined 72 patients (mean age 57.6 ± 0.8 years) with musculoskeletal pathology. The course of SW on the affected area is up to 5-6 procedures with an interval between sessions of 3-7 days. The duration of HiToP therapy ranged from 8 to 10 procedures (3-5 sessions per week). Evaluation of the effectiveness of combined physiotherapy was performed according to the Visual - Analog Scale (VAS) and Short Form Health Survey questionnaire (SF-36).

Results. After a course of combined SW and HiToP physiotherapy all patients with musculoskeletal pathology showed positive dynamics in the pain syndrome. At the same time, according to the visual - analog scale of VAS, there was a significant decrease in pain intensity by an average of 35.8% (p <0.05) compared to baseline before treatment. A probable improvement in the quality of life of patients (SF-36 questionnaire) on the scales of both physical and mental functioning was achieved.

Conclusion. The combined use of SW and HiToP physiotherapy has a positive effect on pain and quality of life in 91.7% of patients with pathology of the musculoskeletal system.
ELECTROCHEMOTHERAPY IN THE TREATMENT OF UNRESECTABLE PANCREATIC CANCER
Authors: Kovalev A. A.
Published: June 2022

Pancreatic cancer (PC) is a malignant tumor with a poor prognosis and an extremely low 5-year survival rate. No more than 10% of patients have local cancer of the pancreas; in the rest, at the time of the initial diagnosis, it is already a systemic disease. In most patients, relapse occurs within the first 6 months after resection and adjuvant therapy. 95% of patients with prostate cancer require palliative therapy.

For 40 years, the results of treatment of metastatic prostate cancer have improved slightly. Gemcitabine monotherapy increased overall survival to 6 months; combinations of gemcitabine with nab-paclitaxel, liposomal irinotecan with 5-FU, or FOLFIRINOX triplet did not achieve 1-year survival.

To date, the survival limit of patients has been reached, and the likelihood of a radical change in the treatment paradigm over the next five years is very small.

The results of current clinical trials examining the effects of new drugs in prostate cancer can be expected in about 8-10 years, with an estimated success rate of about 3%.

A new method of local tumor ablation, which combines intravenous administration of cytostatics (for example, cisplatin or bleomycin) with exposure of tumor cells to constant currents with extremely short and intense pulses (8 nano-pulses of 100 microseconds duration), is the method of electrochemotherapy (clinical therapy).

Unlike radiofrequency, microwave or laser ablation, in which tissues are destroyed as a result of high temperatures with the formation of a zone of coagulation necrosis, the method of electroporation is not associated with thermal exposure, it is safer and can be used in various clinical situations, including in the treatment of cancer. pancreas.

Dynamic Electro-Amplified Chemotherapy (D-EECT) is a safe, simple and effective clinical method for treating large tumor masses. This method opens up a new direction and creates good prospects in the treatment of inoperable, chemoresistant and radioresistant tumors.

In some studies, the median time to progression (PFS) and overall survival (OS) from the moment of diagnosis in patients with unresectable prostate cancer was 22.8 and 30.7 months, respectively, which clearly exceeds the same indicators when using standard methods of anticancer chemotherapy.

The method of electrochemotherapy using Scandinavian ChemoTech AB equipment has already been registered in Ukraine and will soon improve the treatment of patients with complex tumors of various localizations, including those with unresectable forms of pancreatic cancer.
Clinical Features and Principles of Differential Diagnosis of Erysipelas
Authors: Shapoval S. D. , Vasylevska L. A. , Bielinska V. O.
Published: June 2022

Purpose. The purpose is to find out the common and different features of the clinical course of erysipelas from other diseases that can imitate it. Materials and methods. 114 case histories of patients who were hospitalized in the center of purulent-septic surgery in the Non-profit municipal enterprise “City Hospital № 3” in Zaporizhzhia for the period 2019-2020 were analyzed. 123 patients, who underwent hospital treatment in the center during this period of time, were with post-injection abscesses of soft tissue, 184 - with soft tissue abscesses, 203 - with phlegmons of various localizations, 49 - with complicated panaritium, 3 of which -  subcutaneous. Over the past 5 years, 127 patients were consulted in the clinic and other therapeutic, infectious, neurological and other departments of the city. A number of criteria and signs have been identified to differentiate erysipelas from diseases that may have similar clinical symptoms and a number of circumstances that need to be clarified. Results. It is established that the diagnosis of erysipelas does not require special laboratory examination and is made on the basis of examination of the patient, epidemiological history and medical history. Provoking factors in the development of erysipelas are: violation of the integrity of the skin (abrasions, scratches, abrasions, cracks, bruises, injuries); mycoses; a sharp change in temperature (supercooling, overheating); emotional stress; increased insolation. Erysipelas has a characteristic summer-autumn seasonality. In people engaged in physical labor, the disease is registered more often than in other types of work. Hereditary predisposition to the disease is observed in 10-15% of cases. In this regard,  the presence of such factors as congenital and acquired venous insufficiency of the lower extremities, fungal infection of the lower extremities, the presence of postoperative and post-traumatic scars, lymphostasis, diabetes, cardiovascular disease and diseases accompanied by the development of edema, intake of corticosteroids or cytostatics are of essential significance in the development of the disease.
Conclusions. Mathematical modeling between erysipelas and other diseases that have similar syndromes in their clinical picture may be useful in making a differential diagnosis between them.
Matematik Öğretmen Adaylarının Öğretmenlik Uygulaması Dersi Kapsamında Web Destekli Öğretim Uygulamalarına Yönelik Deneyimleri
Authors: GEREZ CANTİMER Gülşah , ŞENGÜL Sare
Published: June 2022

COVID-19 salgın şartları nedeniyle 2020 yılı mart ayından itibaren eğitim faaliyetleri acil uzaktan eğitim olarak yürütülmüştür. Eğitim fakültelerinin son sınıfında okutulan uygulamaya dayalı öğretmenlik uygulaması derslerinin oluşan yeni şartlara göre işlenmek durumunda kalınması birçok farklı deneyimler yaşanmasına sebep olmuştur. Bu kapsamda öğretmenlik uygulaması dersine yönelik uygulamalar web destekli olarak çevrimiçi gerçekleştirilmiş ve öğretmen/öğretmen adayları için farklılaşan deneyimler yaşanmıştır. Çalışmanın amacı matematik öğretmen adaylarının öğretmenlik uygulaması dersi kapsamında web destekli öğretim uygulamalarına yönelik deneyimlerinin incelenmesidir. Nitel araştırma yöntemlerinden durum çalışması deseni tercih edilmiştir. Çalışmanın katılımcılarını 2020-2021 eğitim-öğretim yılı güz ve bahar dönemlerinde öğretmenlik uygulaması dersi kapsamında web destekli öğretim uygulamalarına katılan 7 matematik öğretmen adayı oluşturmaktadır. Veri toplama aracı olarak araştırmacılar tarafından hazırlanan 9 açık uçlu sorudan oluşan değerlendirme formu kullanılmıştır. Çalışma kapsamında formun sadece üç sorusu içerik analizine tabi tutulmuştur. Elde edilen bulgular; web destekli öğretim uygulamalarında edinilen deneyimler, yaşanan olumlu ve olumsuz durumlar ile öğretmenlik uygulaması dersinin katkıları başlıklarında incelenmiştir. Buna göre öğretmen adaylarının edindikleri deneyimler; “teknoloji kullanımı, sınıf yönetimi, mesleki gelişim ve ders içeriği hazırlama” kategorilerinde yer almıştır. Öğretmen adaylarının olumlu durumlara yönelik ifadelerinin en fazla “motivasyon” kategorisinde olmasına rağmen olumsuz ifadelerinin ise “teknolojinin sınırlılığı” kategorisinde olduğu belirlenmiştir. Öğretmen adayları öğretmenlik uygulaması dersinin katkılarına yönelik ise “mesleki gelişim, pedagojik alan bilgisine katkı ve motivasyon” kategorilerinde yer alan açıklamalarda bulunmuştur.