bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploration of Physicochemical, Phytochemical, and HPTLC Analysis of Arputha Mathirai: A Siddha Herbo Mineral Formulation for Poly Cystic Ovarian Syndrome (PCOS)
Authors: Begum G. Dowlathunnissa , Anbu N.
Published: July 2023

Aim: The aim of this study was to explore the physicochemical, phytochemical and HPTLC analysis of the Siddha herbomineral formulation, Arputha Mathirai (AM), in tablet form, for its potential in treating PCOS (Poly Cystic Ovarian Syndrome). The objective was to analyze the tablet and assess its physicochemical properties, as well as the presence of bioactive compounds derived from plant sources.

Place of Study: The physicochemical and phytochemical analysis was conducted at The Tamilnadu Dr.MGR Medical University, located at No.69, Anna Salai, Guindy, Chennai – 600 032. The High-Performance Thin Layer Chromatography (HPTLC) was carried out at Noble Research Solutions in Kolathur, Chennai – 600 099.

Materials and Methods: Arputha Mathirai, the Siddha herbomineral formulation, was prepared in compliance with Good Manufacturing Practices (GMP) guidelines. The formulation underwent a thorough analysis of its physicochemical and phytochemical properties at The Tamilnadu Dr.MGR Medical university, Guindy, Chennai. The analysis was conducted following the standards set by the Pharmacopoeial Laboratory for Indian Medicine (PLIM) in accordance with the guidelines established by AYUSH (Ayurveda, Yoga, Unani, Siddha, Homoeopathy), the governing body for traditional health systems in India. HPTLC was peformed at Noble Research Solutions, Kolathur, Chennai – 600 099.

Results: Physico-chemical analysis of AM showed 10.08% of loss on drying at 1050 C, 15.39% total ash value, 2.45% acid-insoluble ash, 12.18% water-soluble ash, 20.55% water-soluble extraction, and 8.46% alcohol-soluble extraction. According to the phytochemical analysis of AM, alkaloids, carbohydrates, saponins, flavonoids, diterpenes, gum, and mucilage were all found in the sample. Additionally, it demonstrated the absence of quinones, tannins, and phenols. HPTLC finger printing analysis of the sample revealed the presence of five prominent peaks corresponding to the presence of five versatile phytocomponents present with in it. Rf value of the peaks ranged from 0.02 to 0.56.

Conclusion: The findings of this study provided a comprehensive understanding of the physicochemical properties, bio active phytochemicals and phytocomponents of Arputha Mathirai (AM). These results contribute to establishing the nature of the formulation's composition and its safety profile. Moreover, the standardization of the tablet formulation based on these parameters supports its suitability for therapeutic use in the treatment of PCOS. These outcomes validate the quality and potential effectiveness of AM in addressing PCOS, enhancing its credibility as a viable treatment option.
Midline-Sparing Interapophysealaminar Decompression Technique for Management of Lumbar Stenosis in Pediatric Achondroplasia
Authors: Podkovik Stacey , Martins Kevin N. , Ghanchi Hammad , Hanak Brian W.
Published: July 2023

Introduction: Achondroplasia is the most common form of short-limb dwarfism in humans, with an incidence of 1 in 25,000–40,000 live births. About one-third of achondroplasia patients will require operative intervention for lumbar spinal stenosis, generally presenting with progressive neurogenic claudication. The anatomy of the achondroplastic lumbar spine, with shortened pedicles, hypertrophic zygapophyseal joints, and thickened laminae frequently results in the development of multilevel interapophyseolaminar stenosis, while stenosis is usually absent at the mid-laminar levels secondary to pseudo-scalloping of the vertebral bodies. Treatment remains controversial, as disrupting the posterior tension band with complete laminectomies in the pediatric population puts patients at risk of developing post-laminectomy kyphosis. Case Presentation: A 15-year-old girl with achondroplasia presented to clinic with debilitating neurogenic claudication in the setting of multilevel lumbar interapophyseolaminar stenosis. We present a technical case report of her successful surgical treatment using a midline posterior tension band sparing modification to the interapophyseolaminar decompression technique proposed by Thomeer et al. [J Neurosurg. 2002;96(3 Suppl l):292–7]. Conclusion: We demonstrate that an adequate interapophyseolaminar decompression can be achieved through the performance of bilateral laminotomies, bilateral medial facetectomies, and undercutting of the ventral spinous process while preserving supraspinous and interspinous ligament attachments. Given the generally multilevel nature of lumbar stenosis and longer life expectancies of pediatric achondroplasia patients, decompressive surgical interventions must aspire to minimize disruption of spine biomechanics if fusion surgery is to be avoided.
Η συσχέτιση των RAGEs με τη στεφανιαία νόσο
Authors: Τσιρέμπολος Γεώργιος
Published: July 2023

Υπάρχουσα γνώση και σκοπός: Οι RAGE με τους προσδέτες τους AGEs και τις πρωτεΐνες της ομάδας S100 αποτελούν σημαντικούς μεσολαβητές της φλεγμονής και του οξειδωτικού stress, ενώ η εκκρινόμενη ισομορφή των RAGE (sRAGE) δρώντας ως ΄δόλωμα΄ και η αντιοξειδωτική πρωτεΐνη DJ-1/PARK7 εμφανίζουν αντιαθηρωματικές δράσεις. Στην παρούσα μελέτη εξετάσαμε εάν τα sRAGE και οι προσδέτες τους AGEs, S100A8/A9, S100B και S100A12 καθώς και η πρωτεΐνη DJ-1 σχετίζονται με την παρουσία αγγειογραφικά επιβεβαιωμένης στεφανιαίας νόσου (ΣΝ) σε ασυμπτωματικούς ασθενείς με και χωρίς σακχαρώδη διαβήτη. Μέθοδοι και αποτελέσματα: Τα επίπεδα των RAGE προσδετών, των sRAGE και της DJ-1 υπολογίστηκαν στο πλάσμα 50 ασθενών με αγγειογραφικά επιβεβαιωμένη ΣΝ και 50 ‘υγιών’ ατόμων παρόμοιας ηλικίας με στεφανιαία αγγεία χωρίς κριτικές στενώσεις που αποτέλεσαν και την ομάδα ελέγχου. Στο συνολικό στατιστικό δείγμα, τα μειωμένα επίπεδα των sRAGE και τα αυξημένα επίπεδα της ιντερλευκίνης-6 (IL-6), S100B, S100A12 καθώς και του λόγου AGEs/sRAGE συσχετίστηκαν με την παρουσία ΣΝ. Στην υποομάδα των ασθενών χωρίς σακχαρώδη διαβήτη (n=72), τα μειωμένα επίπεδα των sRAGE και της DJ-1 και τα αυξημένα επίπεδα της IL-6 και του λόγου AGEs/sRAGE συσχετίστηκαν με την παρουσία ΣΝ. Στην πολλαπλή (multivariable) ανάλυση παλινδρόμησης που ακολούθησε, ο λόγος AGEs/sRAGE αναδείχθηκε ως ανεξάρτητος προγνωστικός δείκτης της ΣΝ τόσο στο συνολικό στατιστικό δείγμα (p= 0.034, OR=1.247, [95%CI: 1.024, 1.0519]) όσο και στην υποομάδα των ασθενών χωρίς σακχαρώδη διαβήτη (p=0.021, OR=1.363, 95%CI [1.048, 1.771]), πάνω από τους καθιερωμένους παράγοντες καρδιαγγειακού κινδύνου. Συμπέρασμα: Οι μεταβολές της συγκέντρωσης στο πλάσμα των φλεγμονωδών μεσολαβητών του άξονα των RAGE συνδέονται με την αθηροσκλήρωση και τα αυξημένα επίπεδα του λόγου AGEs/sRAGE εμφανίζουν ανεξάρτητη συσχέτιση με την παρουσία ΣΝ σε ασυμπτωματικούς ασθενείς και ως εκ τούτου θα μπορούσαν να αποτελέσουν έναν νέο βιοδείκτη με στόχο την πρόβλεψη της ΣΝ. Επιπλέον, η πρωτεΐνη DJ-1 αναδύεται ως υποσχόμενος βιοδείκτης οξειδωτικού stress σε στεφανιαίους ασθενείς χωρίς σακχαρώδη διαβήτη, εύρημα που αξίζει περαιτέρω έρευνας.
Direitos fundamentais, igualdade e atuação do Judiciário
Authors: Pereira Maroubo Felipe
Published: July 2023

O debate sobre a efetividade dos direitos fundamentais é uma ferramenta elementar para afastar o racismo estrutural e a desigualdade social. Estes fundamentam a perversidade de práticas institucionais e culturais, conscientes ou inconscientes, do uso da raça ou etnia como fundamento sistemático de discriminação pela distribuição de privilégios e repartição injusta dos ônus. Em vista disso, o Estado implementou políticas promocionais, baseadas no critério racial, para conferir qualidade de vida e justiça social a uma parcela populacional historicamente alijada de seus direitos e atingida diariamente com ações discriminatórias em razão de sua cor. Na primeira parte desse trabalho, oferecem-se as teorizações sobre o tema das ações afirmativas, com destaque às cotas raciais, para discutir qual a influência do sistema de direitos humanos, dos princípios da igualdade e da diversidade, bem como o papel do direito na racionalização e na justificativa da política afirmativa. Logo depois, oferece-se uma leitura constitucional das cotas étnico-raciais, balizando-se nas decisões proferidas em ações de controle concentrado pelo Supremo Tribunal Federal, com foco em concursos e processos seletivos. O intuito é verificar os limites de atuação do Judiciário e os parâmetros decisórios relacionados às cotas étnico-raciais. Por fim, levantam-se os dilemas atuais impostos à igualdade material. São questões que, se não enfrentadas, poderão provocar prejuízos ainda maiores à legitimidade da atuação dos poderes da República na reserva de vagas para negros em órgãos e entidades públicas.
“Babyveillance” e “oversharenting” à luz da proteção dos direitos fundamentais da criança e do adolescente
Authors: Barboza Sanhudo Victória , Paulino da Rosa Conrado
Published: July 2023

O presente artigo tem por objetivo expor algumas complexidades da sociedade contemporânea, em especial no que toca à superexposição do público infantojuvenil e, com base em pesquisa empírica realizada pelos pesquisadores, pretende também refletir acerca da visão dos pais a respeito da exposição dos filhos em ambiente virtual e da importância da proteção à privacidade infantil. Com a finalidade de promover o trabalho, adotou-se o método dedutivo com a utilização de metodologia quali-quantitativa. Concluiu-se que crianças e adolescentes não ficam imunes à exposição inerente à sociedade do espetáculo e da informação, sendo, muitas vezes, expostos por seus genitores; que os fenômenos do oversharenting e babyveillance apresentam riscos aos direitos de personalidade dos filhos, em especial imagem, intimidade, vida privada e respeito; que a maioria dos pais entrevistados na pesquisa autoral já publicou fotos do filhos nas redes sociais sem pedir sua autorização e que mais da metade já refletiram que essas publicações podem ter impactos futuros negativos, a depender do conteúdo postado; que a tutela da privacidade infantil é medida que se impõe na sociedade contemporânea como forma de respeito à doutrina da proteção integral, adotada pelo ordenamento brasileiro.
CHARACTERISTICS OF SEDIMENT DISTRIBUTION AND PROSPECTS OF MARINE PLACERS IN SHALLOW COASTAL WATERS OF BINH DINH PROVINCE
Authors: Hieu Trinh The , Dan Nguyen Dinh
Published: July 2023

This paper presents characteristics of distribution of sediment types in shallow coastal waters (0–50 m water) in Binh Dinh province. The results show that sediments of the surface layer of the studied area have a rather complicated distribution, reflecting many sedimentation periods, in which the sandy sediment type is predominant. They consist of eight types of sediment and are divided into five major zones of sediment from the shore to the corresponding depths: From shore to 5 m, 6–24 m, 31–33 m, 35–47 m, and from 47 m or more. The paper also outlines the heavy mineral prospects contained in the sediments, including: Ilmenite, rutile, zircon, anatase, monazite, magnetite. Heavy minerals are concentrated mainly in the grain size from 0.125–0.25 mm, among which ilmenite is predominant with content in the heavy range of 65.5–83.43% and is mainly distributed in the type of fine sand deposits at depths from 5 m to 24 m. Based on that, it is possible to delineate five prospective areas within the study area.
CHARACTERISTICS OF ENVIRONMENTAL GEOCHEMISTRY IN SURFACE SEDIMENT OF TAM GIANG - CAU HAI LAGOON FORMATIONS (THUA THIEN HUE PROVINCE)
Authors: Khoi Nguyen minh , Anh Vu Thu , Hiep Pham Quoc , Quang Ngo Van , Pho Nguyen Van
Published: July 2023

In this paper introduced the results of a new study on the characteristics of environmental geochemistry in surface sediment of Tam Giang - Cau Hai lagoon formations. That is environmental factors that designed the sediment formations such as Ph, Eh, and contribution of the elements in sediment such as N, P, C, S, and heavy metals. By comparison with the previously results that are  associated with observation of seasons were taken the variational trend of sedimentary environment in study area.
Constitutional status of legal professions and legal self-government
Authors: Bałaban Andrzej
Published: July 2023

Konstytucja normuje status zawodów prawniczych dość obszernie w art. 17. Status konstytucyjny zabezpiecza te zawody przed dowolnością regulacji ustawowej i złą praktyką realizacji
ustawy. Dodatkowo pozycję zawodów prawniczych zabezpiecza możliwość tworzenia samorządu, do którego stosują się bardzo liczne wartości i zasady konstytucyjne.
دراسة حركية الاستخلاص المحفز بالأمواج الميكروية للمركبات الفعالة من أوراق إكليل الجبل
Authors: Al-Mnsour Eman
Published: July 2023

نظراً لأهمية عملية الاستخلاص في الكثير من المجالات الهندسية والطبية، وتزامناً مع العودة إلى الاهتمام الكبير بالنباتات الطبية، تمَّ في هذا البحث دراسة العوامل المؤثرة على عملية الاستخلاص المحفز بالأمواج الميكروية للمركبات الفعالة من اوراق إكليل الجبل وتحديد شروط الاستخلاص الأمثل التي تعطي القيمة الأعلى لنسبة الاستخلاص. ومن اجل توصيف عملية الاستخلاص والتوصل إلى معرفة آلية العملية، تمَّ إجراء الدراسة الحركية بتطبيق خمسة نماذج حركية على الاستخلاص المحفز بالأمواج الميكروية وللمستخلص الكحولي الذي أعطى أفضل النتائج.  تؤكد النتائج ان الكحول الإيثيلي 80% كان الأفضل حيث اعطى أعلى نسبة استخلاص عند الزمن 6.5 دقيقة واستطاعة قدرها 720 واط, أما بالنسبة للنماذج الحركية فقد تمَّ تطبيق خمسة نماذج هي : نموذج الانتشار بشكل قطع زائد, نموذج  قانون الطاقة،  نموذج القانون  الأول، نموذج ايلوفتش، ونموذج قانون فيك الثاني في الانتشار، وقد بينت النتائج ان جميع النماذج المدروسة تلائم عملية الاستخلاص المحفز بالأمواج الميكروية للمركبات الفعالة من أوراق إكليل الجبل بقيم مرتفعة لمعامل الارتباط اكبر من 0.96 وقيم منخفضة لكل من الجذر التربيعي النسبي و الانحراف النسبي المطلق حيث كانت جميع القيم أقل من 10%، وعليه فقد تمَّ حساب الثوابت الحركية الخاصة بهذه النماذج.
Effect of different pretreatment methods on drying characteristics and quality of wolfberry (Lycium barbarum) by radio frequency-hot air combined segmented drying
Authors: Xu Yanrui , Wan Fangxin , Zhang Qian , Zang Zepeng , Jiang Chunhui , Wang Tongxun , Shang Jianwei , huang xiaopeng
Published: July 2023

In this study, fresh wolfberry in the current season was used as the experimental material and a radio frequency (RF)-hot air combined segmented drying process was adopted for berry preservation. Ultrasonic treatment, hot water blanching, sucrose infiltration, ultrasonic & blanching, ultrasonic & infiltration, and NaOH and NaCl solution impregnation were used for pre-treatment of combined drying. Taking natural drying and conventional Na2CO3 dewaxing treatment as the control group, the effects of different pretreatment methods on drying characteristics, quality, and microstructure of wolfberry during combined drying were investigated. The drying time after ultrasonic and blanching pretreatment was the shortest(13.5h), which effectively retained total flavonoids(1.79mg/g) and enhanced their antioxidant activity(I = 60.78%). NaCl impregnation treatment significantly increased the total phenol content(8.77 mg/g). The retention rate of soluble sugar (0.73 g/g), ascorbic acid (3.96mg/100g), betaine(2.72%), and other nutrients increased significantly after ultrasonic and infiltration treatment, while the color, rehydration rate and microstructure were better than other treatment methods. The Weibull distribution function can accurately describe the RF-hot air combined drying process of Lycium barbarum after different pretreatment, and simulated results were consistent with the results of the combined drying characteristic curve of Lycium barbarum. The aim of this study was explored suitable pretreatment methods to improve the drying rate and ensure the quality of dried products of wolfberry.
The Therapy Progress Scale: A Brief Measure of Life Functioning for Routine Administration in Measurement-Based Care (Preprint)
Authors: Bugatti Matteo , Dong Yixiao , Owen Jesse , Richardson Zachary , Rasmussen Wendy , Newton Douglas
Published: July 2023

UNSTRUCTURED

Measurement-based care (MBC) is an evidence-based practice endorsed by the American Psychological Association and supported by strong research evidence. MBC is underpinned by the routine administration of assessments supporting a data-driven approach to clinical decision making. Nonetheless, there is a need for brief, non-proprietary measures assessing non-symptom-based treatment outcomes. The present study examined the psychometric properties of the Therapy Progress Scale (TPS), a four-item measure that assesses patients’ perspective of treatment progress in multiple life functioning domains. The sample included 36,420 clients (sex: 29% male, 66% female, 5% missing; race/ethnicity: 55.5% White, 31.5% Racial/Ethnic Minority [REM], and 13% missing) from a practice-research group of private practitioners. The TPS demonstrated a one-factor solution with high reliability estimate. Additionally, the factor structure was consistent across client sex and race/ethnicity. There were moderate negative correlations with symptom-based measures (i.e., PHQ-9, GAD-7). With a subsample, the test-retest correlation was also strong. Implications for research and practice are provided.
HAMBATAN KOMUNIKASI INTERPERSONAL SELAMA PROSES PEMBELAJARAN JARAK JAUH
Authors: Yudhistira Gabriel Alexander , Trihastuti Maria Claudia Wahyu
Published: July 2023

Hambatan komunikasi adalah kondisi yang menghambat kelancaran komunikasi antara dua orang atau lebih. Jenis hambatan komunikasi yakni hambatan mekanik, semantik, dan manusiawi. Penelitian ini bertujuan untuk mengetahui hambatan komunikasi interpersonal yang dialami siswa kelas 11 IPA selama PJJ. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan teknik pengumpulan data berupa instrumen skala penilaian yang terdiri dari 42 pernyataan valid dengan reliabilitas instrumen sebesar 0,951. Teknik analisis data penelitian menggunakan teknik statistik deskriptif. Hasil penelitian terhadap 52 siswa menunjukkan sebagian besar siswa mengalami hambatan komunikasi pada klasifikasi rendah (51,92%). Hambatan komunikasi interpersonal yang dominan dialami siswa adalah hambatan semantik dengan indikator yang dominan yaitu kurang percaya diri dan tidak mampu berkomunikasi dengan lancar saat PJJ. Peneliti memberikan saran kepada Guru BK, untuk memberikan layanan layanan bimbingan klasikal/ kelompok dan konseling kelompok/ individual untuk mengatasi hambatan ketidakpercayaan diri siswa dalam berkomunikasi secara interpersonal. Saran diberikan pula kepada Mahasiswa BK agar dapat memberikan topik layanan psikoedukasi kepada siswa usia remaja terkait dengan topik seperti meningkatkan kepercayaan diri, meningkatkan keterampilan asertif, dan cara memberikan pendapat.
DAMPAK PENGGUNAAN GAWAI TERHADAP KARAKTER GEMAR MEMBACA DI KELAS V SD STRADA BINA MULIA 1
Authors: Utama David Setya , Stevanus Ivan
Published: July 2023

Gadget adalah teknologi yang diciptakan oleh manusia untuk mempermudah hidup. Salah satu manfaat yang dapat diperoleh dari perangkat tersebut adalah membantu siswa untuk mencari bahan pelajaran, buku, dan menonton video pembelajaran. Namun gadget juga memiliki sisi negatif, seperti; permainan dan penipuan. Tujuan penelitian yang ingin dicapai adalah untuk mengetahui dampak penggunaan gadget terhadap karakter gemar membaca siswa kelas VD SD Strada Bina Mulia 1. Jenis penelitian yang digunakan adalah kuantitatif dengan teknik pengumpulan data (kuesioner), Teknik analisis data yang digunakan adalah uji regresi sederhana. Hasil penelitian ini menunjukkan pengaruh penggunaan gawai terhadap karakter suka membaca diperoleh nilai Y=13,314+0,652X, didukung nilai signifikansi 0,000<0,05 dan uji t hitung 8,103>2,048. Guru dapat membimbing siswa untuk secara konsisten menggunakan gawai sebagai alat yang dapat melatih kecintaan membaca mereka, dan sekolah dapat membantu menyediakan bacaan digital dan kemudahan akses bagi siswa.
Strategi Kampanye Public Relations Dalam Membangun Kesadaran Tentang Kesehatan Seksual (Studi Kasus: “Hotel For Play”)
Authors: Mohammad Shihab
Published: July 2023

The importance of public awareness of sexual and reproductive health is often underestimated. This is because some Indonesian people still consider that discussion on sexual health is taboo. In fact, the lack of awareness of sexual health can lead to unplanned pregnancies and transmission of sexually transmitted diseases. This research is conducted to analyze the implementation of the “Hotel For Play” public relations campaign in building awareness sexual health awareness. All data used in this study come from reliable documents, including reputable news articles, journal articles, social media content relevant to the campaign, and company websites. The results showed that this campaign was carried out through special events themed as educational exhibitions and alliances with Tiktok creators and also sexual health practitioners. Information disseminated by Tiktok creators and journalists also create audience interest in participating in this campaign.

ABSTRAK

Pentingnya kesadaran masyarakat tentang kesehatan seksual dan reproduksi masih sering disepelekan. Sebagian masyarakat Indonesia masih menganggap bahwa kesehatan seksual merupakan hal yang tabu untuk diperbincangkan. Padahal, kurangnya kesadaran kesehatan seksual dapat berkontribusi pada kehamilan yang tidak direncanakan dan penularan penyakit menular seksual. Penelitian kualitatif ini dilakukan untuk menganalisa implementasi kampanye public relations “Hotel For Play” dalam membangun kesadaran tentang kesehatan seksual. Seluruh data yang digunakan pada penelitian ini berasal dari dokumen yang terpercaya, di antaranya artikel berita bereputasi, artikel jurnal, konten media sosial yang relevan dengan kampanye, dan website perusahaan. Hasil penelitian menunjukkan bahwa kampanye ini dilakukan dengan acara khusus bertema pameran edukatif dan aliansi bersama kreator Tiktok serta praktisi kesehatan seksual. Informasi yang disebarkan oleh para kreator Tiktok dan wartawan juga membantu menciptakan ketertarikan serta minat audiens untuk berpartisipasi pada kampanye ini. Dalam satu bulan, kampanye edukasi seksual ini berhasil mendatangkan 30 ribu audiens pameran berusia minimal 17 tahun; menjangkau 13 juta penonton di Tiktok; dan menghasilkan 500 konten di media sosial Instagram.
A comparative study on the effectiveness of negative pressure wound therapy versus conventional dressing in patients post skin grafting procedure
Authors: Sriya Gollamudi  , Kalpana Vineet  , Vineet Mannan  , Narayana Venkateshappa  , Basavarajaiah DM
Published: July 2023

An essential biological layer for hemostasis is the skin surface. Therefore, it is crucial to restore the skin surface, even while the restoration of the underlying tissues can wait. By restoring collagen, providing biological occlusion, and protecting the wound, skin grafts aid wound healing and are an important technique to improve the prognosis. Since negative pressure wound therapy (NPWT) has been increasingly used in the health care sector for the management of different kinds of wounds by applying negative pressure to the wound bed, this cutting edge therapy can hasten the healing of both acute and chronic wounds. In this pragmatic approach, the present study was carried out at Vydehi Institute of Medical Sciences & Research Centre's Department of General Surgery, Bengalore, between (2018 and 2020. A total of 48 patients were included in this study, and we categorised them into two groups: Group 1 was the conventional group, and Group 2 was the NPWT. The data was collected and analyzed using SAS software. As per the findings, males comprise 30 (62.5%) and females 18 (37.5%), with a mean age of 48.96 +/-11.64 years in the conventional group and 47.67 +/- 13.12 years in the NPWT group. Most of the ulcers were located in the foot (39.58%). Graft uptake was more superior in patients who received NPWT (95.83%) when compared to the conventional group, showing a significant difference (p <0.001). All 24 patients in the NPWT group had no complications or further requirement for revision surgery, whereas 6 patients in the conventional group (25%) required revision surgery due to postoperative complications. The mean duration of hospital stay was shorter in patients in the NPWT group (11.38 +/- 1.06 days) when compared to the Conventional group (18.54 +/- 3.01 days), with a significant difference (p <0.001). According to the study findings, the use of sub-atmospheric pressure dressings in the form of vacuum assisted closure has been demonstrated to be a potential method of treatment for treating wounds and enhancing the results of skin grafting, especially in patients who have had skin grafting.
Prospects for Transparency In International Commercial Arbitration: Will Indonesia Rise to The Challenge of Introducing Transparency Into Its Arbitration System?
Authors: Evelyn
Published: July 2023

This paper weighs the pros and cons of confidentiality in arbitration and discusses how transparency can enhance the legitimacy of arbitration. Find out how the players can contribute to promote transparency. How arbitration bodies, parties to arbitration, and legislative bodies contribute to promoting predictability and legitimacy in international commercial arbitration (ICA) without sacrificing confidentiality. Explore the possibility of arbitration joining the ICA trend towards transparency. Finally, itdiscusses the possibility of publishing the full award, and whether Section 69 of the English Arbitration Act could be a better solution to promote transparency and accountability.
DENTAL CARIES PREVALENCE AND ORAL HEALTH STATUS IN 3 TO 15 YEARS OLD SCHOOL STUDENTS IN ABBOTTABAD CITY, PAKISTAN: AN ASSESSMENT SURVEY
Authors: Shad Samia , Anee Qurat-Ul-Ain , Shazia Liaquat  , Khattak Faryal , Basit Khola , Waheed Ullah
Published: July 2023

Aim:

To assess the score of dental caries (hereinafter referred to as Carries) and status of dental hygiene practices in school-going children aged 3-15 years with specific diagnosis and timely referral for the required treatment, according to each participant's oral health condition.

Materials & Methods:

This study was performed on school-going children of ages 3 to 15 years in Abbottabad City, via a cross-sectional survey method. Non-probability convenient sampling technique was used. Data were collected during the ‘Dental Awareness Programme’ from different schools in Abbottabad. Total n=634 were screened and caries score of DMFT/dmft index and orthodontic treatment need were observed and recorded. Also, questions about oral hygiene practices were asked like frequencies of tooth brushing & sugary diet intake from school children and a written record was maintained on structured survey form. Gathered data was import in IBM-SPSS file version 21. Descriptive statistics were used to verify the standard deviation and arithmetic mean of all variables and the comparison  between variables like, Caries score; intake of sugary diet daily, age & different school were made and presented in tables & figures.

Results:

This research study shows high number of Caries  cases 69.4% (Mean= 2.76, SD= 2.738, n= 634). A higher score was observed and recorded for the D-component in the total DMFT score; however habit of daily tooth brushing and maximum intake of sugary diet were found common among all the school-going children.

Conclusion:

A high number of caries-affected cases were found, in this study, among school-going children and that is a critical oral health state. Children themselves are negligent towards their needs for good oral health and necessary professional care. Increased DMFT scores of ‘mostly decayed’ and ‘less filled’ teeth were founded. It was recorded that tooth brushing by children is not correctly performed, mechanically. Also, children were found to eat a sugary diet daily. The value of a “preventive approach” can lead to the good oral hygiene of children.
Effectiveness of Surface Electromyographic Biofeedback-triggered Neuromuscular Electrical Stimulation on Quadriceps Femoris Torque and Recruitment
Authors: Boucher Tony
Published: July 2023

Context: Injury and pathology often result in physiological impairments including decreased strength, muscular performance, and arthrogenic muscle inhibition. Neuromuscular electrical stimulation initiated by a surface electromyographic biofeedback threshold (sEMG-triggered NMES) is effective in neurological populations but has been minimally applied to orthopedic populations.
Objective: The purpose of the study was to investigate the effectiveness of sEMG-triggered NMES on maximal isometric knee extensor torque and neuromuscular recruitment.Design: Counterbalanced crossover study design.Setting: University research laboratory.
Participants: Twenty-two healthy persons (14 men, 8 women; age = 22.9 ± 4.7 years; height = 171.7 ± 6.1 cm; mass 76.6 ± 19.4 kg) participated.Intervention: Maximal isometric knee extensor torque @ 60° knee flexion was assessed with sEMG-triggered NMES applied to the quadriceps femoris compared to voluntary contraction alone on two separate testing sessions 2 to 7 days apart.Main outcome measures: Peak torque, peak torque to body weight ratio, and time to peak torque were assessed.
Results: Analysis of variance (ANOVA) showed peak torque produced with sEMG-triggered NMES (191.6 ± 59.8 Nm) was significantly greater than without (167.4 ± 54.7 Nm). Average Peak torque to body weight ratio with sEMG-triggered NMES (224.8 ± 66.9 Nm) produced significantly greater torque than without (196.4 ± 51.1 Nm). Time to peak torque with the sEMG-triggered NMES (3.3 ± 1.6 sec) was significantly faster than volitional contractions (4.2 ± 2.1 sec) during the sEMG-triggered NMES testing session and significantly quicker than all volitional contractions (3.9 ± 2.7 sec) for both testing sessions.
Conclusions: sEMG-triggered NMES is more effective in producing greater quadriceps femoris torque while producing quicker neuromuscular recruitment than voluntary contractions alone. Results support the use of sEMG-triggered NMES applications to improve knee extensor torque and recruitment of the QF to influence arthrogenic muscle inhibition, facilitate QF recruitment, and improve strength.
Key Words: sEMG-triggered NMES; Torque; Recruitment; Quadriceps
Effects of Background Porosity on Seismic Anisotropy in Fractured Rocks: An Experimental Study
Authors: Zhang Yuangui , Di Bangrang , Gao Feng , Li Lei
Published: July 2023

Fractures are widely distributed in the subsurface and are crucial for hydrocarbon, CCS, offshore infrastructure (windfarms), and geothermal seismic surveys. Seismic anisotropy has been widely used to characterize fractures and has been shown to be sensitive to background matrix porosities in theoretical studies. An understanding of the effects of background porosity on seismic anisotropy could improve seismic characterization in different fractured reservoirs. Based on synthetic rocks with controlled fractures, we conducted laboratory experiments to investigate the influence that background porosity has on P-wave anisotropy and shear wave splitting. A set of rocks containing the same fracture density (0.06) with varying porosities of 15.3%, 22.1%, 26.1% and 30.8% were constructed. The P- and S-wave velocities were measured at 0.5 MHz as the rocks were water saturated. The results show that when porosity increased from 15.3% to 22.1%, P-wave anisotropy and shear wave splitting exhibited slight fluctuations. However, when porosity continued to increase to 30.8%, P-wave anisotropy declined sharply, whereas shear wave splitting stayed nearly constant. The measured results were compared with predictions from equivalent medium theories. Qualitative agreements were found between the theoretical predictions and the measured results. In the Eshelby–Cheng model, an increase in porosity reduces fracture-induced perturbation in the normal direction of the fracture, resulting in lower P-wave anisotropy. In the Gurevich model, an increase in porosity can reduce the compressional stiffness in parallel directions to a larger extent than that in perpendicular directions, thus leading to lower P-wave anisotropy.
Updates on the Management of Hyperglycemia in Hospitalized Adult Patients
Authors: Razavi Nematollahi Laleh , Omoregie Caitlin
Published: July 2023

The prevalence of diabetes is rising globally; currently, 537 million people worldwide and 37.3 million people in the US are affected. Patients with diabetes have a four-times-greater risk of hospitalization with longer hospital stays and a greater chance of readmission compared to patients without diabetes. Spending on diabetes care as a proportion of global GDP is also projected to increase from 1.8% in 2015 to 2.2% in 2030. The largest component of this medical expenditure is inpatient care in hospitalized patients, accounting for USD 69.7 billion of the total medical cost. Hospitalized patients can develop hyperglycemia without a history of pre-existing diabetes. It has been shown that hyperglycemia in patients without a history of diabetes is also associated with poor hospital outcome. In this review, we discuss the adverse effects of hyperglycemia and hypoglycemia on hospital outcomes; we review recent glycemic targets, recent guidelines’ recommendations, and landmark trials with a brief review on discharge planning, updates on hyperglycemic emergencies, and the use of newer technologies in hospitalized patients such as continuous glucose monitoring devices.
Trends in Japanese Research Ethics in the 21st Century: Research Misconduct and Related Policies
Authors: LEE Kyu Won , KIM Ock-Joo
Published: July 2023

Japan and South Korea both have relatively high rates of research misconduct in the biomedical sciences. These two countries also share other relevant characteristics, including being latecomers to research ethics and having hierarchical cultures and competitive research environments. Given these similarities, Korea can learn from Japan’s efforts to eradicate research misconduct. In the 2010s, after experiencing several high-profile cases of misconduct, Japanese authorities implemented measures to combat research misconduct at the national level. However, these measures have so far been outweighed by other policies that aggravate excessive competition and a negative research culture in science and technology. This article argues that the key lesson for Korea from Japan’s experiences fighting research misconduct is that instead of focusing only on research ethics education and punishment, it is necessary to (a) establish a system of manpower training with secure employment in science and technology, (b) abolish the ‘winner takes all’ strategy in research funding, and (c) promote bottom-up policy-making.
Medical Care that Embodies Human Dignity at the End of Life
Authors: AHN Kyongjin
Published: July 2023

Public debates and discussions concerning physician-assisted suicide have recently arisen in South Korea in response to proposals made in the National Assembly for new legislation governing this and other aspects of end-of-life medical care. Two contrasting positions can be discerned in these debates: one position views physician-assisted suicide as respecting patients’ autonomy and guaranteeing their right to a “death with dignity”; the other argues that physician-assisted suicide might be transformed into a “duty to die,” especially since dying care has not yet been well established in Korea. On this latter view, the expansion of hospice for end-of-life care should precede the introduction of physician-assisted suicide. The present article examines these two views in detail and explores the state of end-of-life medical care in Korea.
DETERMINATION OF ELIGIBILITY ZAKAT RECIPIENTS USING ANALYTIC HIERARCHY PROCESS FOR UNIVERSITI TEKNOLOGI MARA CAWANGAN PERLIS STUDENTS
Authors: Wan Shahidan Wan Nurshazelin , Mohamad Nor Nor Azriani , Muhamad Siti Nor Nadrah , Abdul Aziz Azlan , Muhammat Pazil Nur Syuhada
Published: July 2023

The COVID-19 pandemic and the implementation of the lockdown had a significant impact on the country's community life and economic stability, resulting in job losses, school and educational institution closures, and a loss of foreign investment. Implementing home teaching and learning (PdPR) entailed additional costs, such as purchasing internet access, which increased the financial burden on parents. Therefore, Unit Zakat, Sedekah, & Wakaf (ZAWAF) of Universiti Teknologi MARA (UiTM) Cawangan Perlis is responsible for providing immediate financial assistance to UiTM staff and students. ZAWAF has taken proactive action by introducing an online zakat assistance application in March 2020 as an alternative to traditional face-to-face interviews during the pandemic. However, receiving a large number of applications and numerous reasons why students apply for zakat assistance to be processed urgently has affected ZAWAF during the zakat evaluation process. The Analytical Hierarchy Process (AHP) method has been used to assist ZAWAF in classifying which zakat applicants are eligible to receive zakat assistance immediately and ranking the important factors. The results revealed that the less capable family had been the most important factor, having the highest judgment and getting the highest average ranking from the three experts interviewed by Zawaf. The AHP method can be used to determine the other factors that contribute to the eligibility of students to receive zakat assistance and can help ZAWAF speed up the process of distributing zakat assistance to eligible zakat recipients. Future research can be made using other factors, such as a history of receiving previous zakat assistance and subfactors for each criterion (factor) that can contribute to whether students are eligible to receive zakat assistance.
On the hierarchy problem of particle physics
Authors: Bhattacharjee Deep
Published: July 2023

This paper attempts to delve into the hierarchy problem of particle physics taking into consideration the Calabi-Yau manifolds and D(p)-Branes.
ОСОБЕННОСТИ ПРИМЕНЕНИЯ КОММЕРЧЕСКИМИ ОРГАНИЗАЦИЯМИ ОБЩЕГО И СПЕЦИАЛЬНЫХ РЕЖИМОВ НАЛОГООБЛОЖЕНИЯ
Authors: Хасанова М.С. , Джабраилова Х.М. , Махматхаджиева Р.С.
Published: July 2023

Налогообложение с давних пор является важнейшей частью любого государства, поскольку налоги обеспечивают возможность функционирования государственных институтов управления, контроля и обеспечения комфортных условий существования населения. Основная часть всех существующих налогов формируется благодаря хозяйственной деятельности предприятий.
Государство создает все условия для того, чтобы хозяйствующим субъектам было удобно платить налоги и сборы: организации, индивидуальные предприниматели имеют право, согласно законодательству Российской Федерации, применить одну из систем налогообложения: общую систему или специальные налоговые режимы. В исследовании рассмотрены системы налогообложения в РФ, отмечены особенности налогообложения ИП и организаций.
ТЕХНОЛОГИЯ БЛОКЧЕЙН И ЭМИССИЯ КРИПТОВАЛЮТЫ. ОСОБЕННОСТИ И ПЕРСПЕКТИВЫ ИСПОЛЬЗОВАНИЯ
Authors: Лайпанов И.М. , Тамбиева Х.М.
Published: July 2023

Технология блокчейн и эмиссия криптовалют нарушили работу различных отраслей, но проблемы и ограничения все ещё существуют. Будущее этих технологий включает в себя CBDCs, интероперабельность, DeFi и криптовалюты, ориентированные на конфиденциальность, формируя глобальную экономику.
Spiel mit Grenzen
Authors: Müller Norbert
Published: July 2023

Die Lagerung von Gefahrstoffen in Deutschland, in Österreich und in der Schweiz wird in den drei Ländern unterschiedlich gehandhabt: Im Beitrag wird ein Vergleich am Beispiel der brennbaren Flüssigkeiten gezogen.
THE ROLE OF THE COMPUTER TOMOGRAPHY IN STAGING AND SURGICAL TREATMENT OF LOCALY DISTRIBUTED STOMACH CANCER
Authors: Boiko V. V. , Lazirskiy V. A. , Krivorotko I. V. , Veseliy A. L.
Published: July 2023

Summary. Aim. Improvement of algorithm of diagnostics of patients with complicated stomach cancer.

Materials and methods. It was shown the analysis of results of surgical treatment of 418 patients with complicated stomach cancer, which got the hospital treatment at GI “V. T. Zaycev Institute of General and Urgent Surgery of NAMS of Ukraine “ from 2010 till 2019, aged 29 till 76.

Results. Patients were exanimated with using of combination of instrumental methods. Goal is total detail examination of pathologic process. SCT has precision of 95-97 % at detecting of cancer, definition of stage – 77-80 %. Endoscopy allows to define the location, spreading of process, to find a pathologic process at starting and precancer stages. There no any ideal oncomarker. Diagnostic precision of CA 72-4 is 28-80 % (40-46 % on the average). According to international guides [5], all patients were performed the diagnostic laparoscopy with researching of washout liquids of abdomen in uncertain cases.

Conclusion. Only complex examination of patients with stomach cancer with using combination of SCT of abdomen, FEGDS with biopsy, laparoscopy can provide total volume of examination, staging and surgical aid.
Undoing Time
Authors: Torres Francisco Sánchez
Published: July 2023

The researchers propose a review on the notion of gender in Antiquity through its sources in order to manifest the dissonances between the systems that regulated social gender in different eras. Our current gender binary is rooted in enlightened medical studies 19th positivism, which rejected the extended previous idea that humans were born within an only sex that presented different degrees of development. Therefore, this previous conception understood that gender was a technology developed for social purposes and dissociated it from the also constructed notion of sex. After analyzing the potentiality of this matter, the authors proceed to examine the notion of the decolonization of classics. Teaching methodologies and focuses will be provided to stimulate this process.
Pemahaman Konsep pada Materi Fungsi Eksponensial Ditinjau dari Gaya Belajar Siswa di SMA
Authors: Wijayanti Rini , Yusmin Edy , Fitriawan Dona
Published: July 2023

Salah satu pemahaman konsep adalah pada materi fungsi eksponensial. Pemahaman terhadap suatu konsep diperoleh dari proses belajar, di dalam mengikuti proses belajar mengajar setiap siswa memiliki karakteristik gaya belajar yang berbeda. Pemahaman konsep dapat ditingkatkan apabila siswa maupun guru mengenali gaya belajar yang digunakan masing-masing siswa. Tujuan dari penelitian ini adalah untuk mengetahui pemahaman konsep pada materi fungsi eksponensial ditinjau dari gaya belajar siswa. Metode dari penelitian ini adalah deskriptif. Instrumen yang digunakan terdiri dari angket gaya belajar, tes pemahaman konsep, dan pedoman wawancara. Subjek dari penelitian ini adalah sembilan orang siswa kelas X SMA. Berdasarkan hasil penelitian menunjukkan bahwa subjek dengan gaya belajar auditori dan kinestetik memiliki kemampuan pemahaman konsep lebih baik dibanding subjek dengan gaya belajar visual. Subjek dengan gaya belajar visual mampu memenuhi dua indikator pemahaman konsep yaitu indikator 1 dan 2, subjek dengan gaya belajar auditorial mampu memenuhi tiga indikator pemahaman konsep yaitu indikator 1, 2, dan 3, subjek dengan gaya belajar kinestetik mampu memenuhi tiga indikator pemahaman konsep yaitu indikator 1, 2, dan 4.
Work Commitment, Motivation, and Job Satisfaction among Traffic Enforcers in Ozamiz City
Authors: Adaza Jason Ray C. , Alegria Jr Rodrigo P. , Broñola Jr Ronald H. , Pang-an Generous Jess D. , Vivares Kristal May S. , Cuevas Jose F.
Published: July 2023

Traffic enforcers play an essential role in society by managing and regulating traffic on the roads. They are responsible for enforcing traffic laws and regulations, directing traffic, and ensuring the safety of motorists and pedestrians. This study determined the level of work commitment, motivation, and job satisfaction among traffic enforcers in Ozamiz City. The respondents of the study include all thirty (30) traffic enforcers in Ozamiz City, Misamis Occidental, Philippines. An adapted survey questionnaire was the primary instrument utilized in gathering data for the study. Results revealed that the traffic enforcers in Ozamiz City were very committed, highly engaged, motivated, and satisfied with their current job. Age does not influence work commitment, but gender, civil status, and job satisfaction do. Similarly, a person’s level of education has an impact on their level of job satisfaction. The researcher recommended that traffic enforcers be encouraged to maintain their efficacy in maintaining public road safety. Furthermore, traffic enforcers should be commended for their high level of dedication, motivation, and satisfaction with their work. A yearly event to recognize outstanding performance should be held, and they should be allowed to undergo training and seminars to enhance their knowledge and skills.
Analysis Of International Shipping Path Determination In Indonesian Archipelagic Sea Lanes III (IASL III) Using Dynamic Programming
Authors: Ernawati Regita , Widodo Pujo , Saragih Herlina JR. , Suwarno Panji , Marsetio Marsetio , Wiranto Surya
Published: July 2023

When a country has made part of its territorial waters open for international shipping, so the country has carried out its obligations as an archipelagic state accompanied by the granting of navigational rights to foreign ships and aircraft. The right of navigation is the right of foreign countries to freely sail along international waters and receive security protection along IASL I, IASL II, and IASL III from archipelagic countries. The determination of Indonesian Archipelagic Crossings creates benefits as well as a challenge to the sovereignty of the archipelagic state. With the change from a closed area to an open area for international shipping, issues related to the safety and security of shipping along archipelagic sea lanes arise. IASL is a guide or reference so that foreign ships do not violate the territorial waters of Indonesia. This study aims to analyze the determination of international shipping lanes at IASL III to obtain the optimal route with minimum mileage. This study was limited to IASL III, namely the IASL III-A route from the Pacific Ocean across the Maluku Sea, Seram Sea, Banda Sea, Ombai Strait, and Sawu Sea. IASL Branch III B: from the Pacific Ocean across the Maluku Sea, Seram Sea, Banda Sea and Leti Strait to the Indian Ocean. IASL Branch III C: from the Pacific Ocean across the Maluku Sea, Seram Sea, Banda Sea to the Arafura Sea. IASL Branch III D: from the Pacific Ocean across the Maluku Sea, Seram Sea, Banda Sea, Ombai Strait and Sawu Sea to the Indian Ocean. IASL Branch III E: from the Indian Ocean across the Sawu Sea, Ombai Strait, Banda Sea, Seram Sea and Maluku Sea combined into 1 (one) route from the Pacific Ocean to the Indian Ocean resulting in the optimal route with the minimum distance obtained from the smallest value at every stage. The selected route is (1. Pacific Ocean-5. Ombai Strait-8. Sawu Sea-9. Indian Ocean) with a distance from the Pacific Ocean to the Ombai Strait is 10,596.55. The Ombai Strait to the Sawu Sea is 211.28. Sawu Sea to the Indian Ocean is 2,978.61. So that the total voyage distance is 13,786.44 Nautical miles (Nm). This study uses quantitative methods and Multistage Graph problem-solving techniques with backward or bottom-up Dynamic Programming methods, as well as secondary data collection such as: documents/journals/books.Keywords— International Shipping Path, Indonesian Archipelagic Sea Lanes III (IASL III), Dynamic Programming.
Diagnostic Des Geo-Helminthes Chez Les Enfants De 1-10 Ans A L’hopital General De Reference De Kintambo A Kinshasa En RDCONGO
Authors: Onembo Gloire Mokange , Atila Daddy Wangima , Kinilange Remy Ndjeshi
Published: July 2023

This end-of-cycle work focused on the diagnosis of soil-transmitted helminths in children aged 1-10 years examined at the General Reference Hospital of Kintambo. The socio-demographic results of those diagnosed revealed that individuals of the male sex dominated over the female sex, with 31 cases or 62% against 19 cases or 38%.        According to the distribution of age groups, children whose age varies from 3-4 years were the most affected. The distribution of people diagnosed according to the positive results of soil-transmitted helminth species showed that Ascaris lumbricoides was the most represented species with a number of 37 children diagnosed out of 50, or 74%.