bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical validation of engineered CRISPR/Cas12a for rapid SARS-CoV-2 detection
Authors: Nguyen Long T. , Rananaware Santosh R. , Pizzano Brianna L. M. , Stone Brandon T. , Jain Piyush K.
Published: January 2022

Background

The coronavirus disease (COVID-19) caused by SARS-CoV-2 has swept through the globe at an unprecedented rate. CRISPR-based detection technologies have emerged as a rapid and affordable platform that can shape the future of diagnostics.

Methods

We developed ENHANCEv2 that is composed of a chimeric guide RNA, a modified LbCas12a enzyme, and a dual reporter construct to improve the previously reported ENHANCE system. We validated both ENHANCE and ENHANCEv2 using 62 nasopharyngeal swabs and compared the results to RT-qPCR. We created a lyophilized version of ENHANCEv2 and characterized its detection capability and stability.

Results

Here we demonstrate that when coupled with an RT-LAMP step, ENHANCE detects COVID-19 samples down to a few copies with 95% accuracy while maintaining a high specificity towards various isolates of SARS-CoV-2 against 31 highly similar and common respiratory pathogens. ENHANCE works robustly in a wide range of magnesium concentrations (3 mM-13 mM), allowing for further assay optimization. Our clinical validation results for both ENHANCE and ENHANCEv2 show 60/62 (96.7%) sample agreement with RT-qPCR results while only using 5 µL of sample and 20 minutes of CRISPR reaction. We show that the lateral flow assay using paper-based strips displays 100% agreement with the fluorescence-based reporter assay during clinical validation. Finally, we demonstrate that a lyophilized version of ENHANCEv2 shows high sensitivity and specificity for SARS-CoV-2 detection while reducing the CRISPR reaction time to as low as 3 minutes while maintaining its detection capability for several weeks upon storage at room temperature.

Conclusions

CRISPR-based diagnostic platforms offer many advantages as compared to conventional qPCR-based detection methods. Our work here provides clinical validation of ENHANCE and its improved form ENHANCEv2 for the detection of COVID-19.
Precise surface control of cathode materials for stable lithium-ion batteries
Authors: Lu Si-Qi , Guo Si-Jie , Qi Mu-Yao , Li Jin-Yang , Cao An-Min , Wan Li-Jun
Published: January 2022

Precise surface control of cathode materials for stable Li-ion batteries: materials design, kinetics control and stabilization mechanism.
One-pot synthesis of multi-substituted conjugated dienones by trapping allene carbocations with active ylides
Authors: Ni Dan , Song Longlong , Zhao Yun , Liu Shunying
Published: January 2022

A rapid construction of multi-substituted conjugated dienones and the resulting diversity-oriented synthesis were established by trapping an allene or propargyl carbocation with active ylides in a one-pot fashion under mild conditions in good to excellent yields.
Upconversion luminescence and optical temperature-sensing properties of LiNbO3:Yb3+/Er3+ nanoparticles
Authors: Tong Xuan , Zhou Xin , Tang Xunze , Min Yonggang , Li XiaoLong , Wang Wenguang , Qian Yannan
Published: January 2022

LiNbO3:Yb3+/Er3+ nanocubes are synthesized by a hydrothermal method. LiNbO3:Yb3+/Er3+ annealed at 1050 °C exhibits a sensitivity of 0.0094 K−1 at 340 K.
Effect of an additive TAB-1 on crystallization behaviors and tensile properties of iPB-1
Authors: Li Jingqing , Bai Ruo , Jiang Shichun
Published: January 2022

The additive TAB-1, able to accelerate II–I transition of iPB-1, can enhance its melt crystallization without negative effects on the tensile properties, revealing a new strategy to improve the performances of the products.
Bridging coordination of acenaphthylene to a Pd3 chain or a Pd4 sheet cluster
Authors: Yamamoto Koji , Sugawa Tsuyoshi , Kondo Mio , Masaoka Shigeyuki , Murahashi Tetsuro
Published: January 2022

The μ3–η2:η2:η2-π-coordination mode or μ4–η5:η2:η3:η2-oxidative π-addition mode of acenaphthylene to a Pd3 chain or a Pd4 sheet cluster was revealed.
Groundwaters in Northeastern Pennsylvania near intense hydraulic fracturing activities exhibit few organic chemical impacts
Authors: Xiong Boya , Soriano Mario A. , Gutchess Kristina M. , Hoffman Nicholas , Clark Cassandra J. , Siegel Helen G. , De Vera Glen Andrew D , Li Yunpo , Brenneis Rebecca J. , Cox Austin J. , Ryan Emma C. , Sumner Andrew J. , Deziel Nicole C. , Saiers James E. , Plata Desiree L.
Published: January 2022

Hydrogeologic transport contributes to limited organic chemical contamination in a region of intense gas extraction, even 10 years post-development.
A novel magnetophoretic-based device for magnetometry and separation of single magnetic particles and magnetized cells
Authors: Abedini-Nassab Roozbeh , Ding Xianting , Xie Haiyang
Published: January 2022

The use of magnetic micro- and nanoparticles in medicine and biology is expanding.
Preparation of heterostructured TiO2/MoS2 for efficient photocatalytic rhodamine B degradation
Authors: Li Ping , Gao Mengyou , Sun Lei , Xu Huizhong , Dong Xiaochen , Lin Jianjian
Published: January 2022

Heterostructured TiO2/MoS2 was prepared via a simple two-step solvothermal approach. The synergistic effect between MoS2 and TiO2 illustrated an enhanced adsorption and improved performance in the photocatalytic degradation of rhodamine B (99.4%).
Overview of the structure, side effects, and activity assays of l-asparaginase as a therapy drug of acute lymphoblastic leukemia
Authors: Wang Nanxiang , Ji Wenhui , Wang Lan , Wu Wanxia , Zhang Wei , Wu Qiong , Du Wei , Bai Hua , Peng Bo , Ma Bo , Li Lin
Published: January 2022

We summarized its structure and mechanism in detail, reviewed the detection approaches, and prospected the development of future detection assays.
Combination of a methylene blue-iodide system with a smartphone-based portable colorimeter for the on-site determination of nitrite
Authors: Khoshmaram Leila , Tabaghchi Sona , Azhar Fahimeh Farshi
Published: January 2022

On-site determination of nitrite using a novel colorimetric method based on bleaching the blue color of methylene-blue and image analysis.
A pyridine based Schiff base as a selective and sensitive fluorescent probe for cadmium ions with “turn-on” fluorescence responses
Authors: Ma Jialin , Dong Yuwei , Yu Zhou , Wu Yan , Zhao Zhen
Published: January 2022

A pyridine based Schiff base probe (PMPA) showed high selectivity and sensitivity towards Cd2+ ions with intense bluish green fluorescence. The sensing mechanism of probe PMPA for detecting Cd2+ was based on the inhibited PET and CHEF processes.
Correction: Nanofibers of polycaprolactone containing hydroxyapatite doped with aluminum/vanadate ions for wound healing applications
Authors: Ashraf Sherif , Ahmed M. K. , Ibrahium Hala A. , Awwad Nasser S. , Abdel-Fattah E. , Ghoniem M. G.
Published: January 2022

Correction for ‘Nanofibers of polycaprolactone containing hydroxyapatite doped with aluminum/vanadate ions for wound healing applications’ by Sherif Ashraf et al., New J. Chem., 2021, DOI: 10.1039/d1nj03455c.
Synthesis of gold nano-mushrooms via solvent-controlled galvanic replacement to enhance phototherapeutic efficiency
Authors: Kang Seounghun , Kwon Namgook , Kang Kyunglee , Ahn Hojung , Kwon Sunbum , Min Dal-Hee , Jang Hongje
Published: January 2022

In galvanic replacement, it was found that the solvent polarity had a significant effect on the formed nanostructure. Hollow-tailed Au nano-mushrooms were synthesized under co-solvent conditions and used in effective cancer phototherapy.
Catalytic and mechanistic studies of a highly active and E-selective Co(ii) PNNH pincer catalyst system for transfer-semihydrogenation of internal alkynes
Authors: Decker David , Wei Zhihong , Rabeah Jabor , Drexler Hans-Joachim , Brückner Angelika , Jiao Haijun , Beweries Torsten
Published: January 2022

A Co(II) PNNH pincer catalyst system for the highly E-selective transfer-semihydrogenation of internal alkynes using ammonia borane and MeOH as the hydrogen source is described. The reaction is proposed to occur via the Co(ii) oxidation state.
Hybrid hydrogels derived from renewable resources as a smart stimuli responsive soft material for drug delivery applications
Authors: Singh Vandana , Prasad Yadavali Siva , Rachamalla Arun Kumar , Rebaka Vara Prasad , Banoo Tohira , Maheswari C. Uma , Sridharan Vellaisamy , Lalitha Krishnamoorthy , Nagarajan Subbiah
Published: January 2022

The design and synthesis of amphiphilic molecules play a crucial role in fabricating smart functional materials via self-assembly.
Visible light responsive metalloporphyrin-sensitized TiO2 nanotube arrays for artificial photosynthesis of methane
Authors: Xiao Tongxin , Chen Ying , Liang Yuning
Published: January 2022

A photocatalyst composed of TiO2 nanotube arrays and a porphyrin (metalloporphyrin) was prepared. The improved photocatalytic performance for CO2 reduction is ascribed to the enhanced charge separation and light absorbance.
Atomically dispersed Mn–N4 electrocatalyst with high oxygen reduction reaction catalytic activity from metal–organic framework ZIF-8 by minimal-water-assisted mechanochemical synthesis
Authors: Kong Ziyan , Liu Tao , Hou Kun , Guan Lunhui
Published: January 2022

Single-atomic Mn–N–C catalyst, which uses ZIF-8 synthesized by a minimal-water-assisted grinding method as the precursor, has high yields and shows high ORR activity in both acid and base solutions.
Strategies for designing more efficient electrocatalysts towards the urea oxidation reaction
Authors: Zhu Dongdong , Zhang Huaiyu , Miao Juhong , Hu Fangxin , Wang Liang , Tang Yujia , Qiao Man , Guo Chunxian
Published: January 2022

In this perspective, five typical strategies are summarized for designing highly active electrocatalysts towards the urea oxidation reaction (UOR).
An indium-induced-synthesis In0.17Ru0.83O2 nanoribbon as highly active electrocatalyst for oxygen evolution in acidic media at high current densities above 400 mA cm−2
Authors: Chen Shi , Wang Changlai , Gao Feiyue , Yang Yang , Huang Minxue , Tong Huigang , Cheng Zhiyu , Wang Pengcheng , Wang Peichen , Tu Jinwei , Zeng Xuehao , Chen Qianwang
Published: January 2022

An In0.17Ru0.83O2 nanoribbon electrocatalyst based on dual-mechanism of micromorphology and electronic structure regulation is applied for acidic OER, the mass activity and current density are up to 1094.90 A gRu−1, and 400 mA cm−2, respectively.
A gradient hexagonal-prism Fe3Se4@SiO2@C configuration as a highly reversible sodium conversion anode
Authors: Zhao Wenxi , Ma Xiaoqing , Yue Luchao , Zhang Longcheng , Luo Yongsong , Ren Yuchun , Zhao Xian-En , Li Na , Tang Bo , Liu Qian , Liu Yang , Gao Shuyan , Alshehri Abdulmohsen Ali , Sun Xuping
Published: January 2022

A gradient hexagonal-prism Fe3Se4@SiO2@C configuration was exquisitely developed and used as an anode for sodium ion batteries, affording an ultrastable cycling lifespan over 4200 cycles with a competitive capacity of 272 mA h g−1 at 20.0 A g−1.
Cross-Language Transfer and Attentional Control in Early Bilingual Speech
Authors: Verbeek Lisa , Vissers Constance , Blumenthal Mirjam , Verhoeven Ludo
Published: January 2022

Purpose:

This study investigated the roles of cross-language transfer of first language (L1) and attentional control in second-language (L2) speech perception and production of sequential bilinguals, taking phonological overlap into account.

Method:

Twenty-five monolingual Dutch-speaking and 25 sequential bilingual Turkish–Dutch-speaking 3- and 4-year-olds were tested using picture identification tasks for speech perception in L1 Turkish and L2 Dutch, single-word tasks for speech production in L1 and L2, and a visual search task for attentional control. Phonological overlap was manipulated by dividing the speech tasks into subsets of phonemes that were either shared or unshared between languages.

Results:

In Dutch speech perception and production, monolingual children obtained higher accuracies than bilingual peers. Bilinguals showed equal performance in L1 and L2 perception but scored higher on L1 than on L2 production. For speech perception of shared phonemes, linear regression analyses revealed no direct effects of attention and L1 on L2. For speech production of shared phonemes, attention and L1 directly affected L2. When exploring unshared phonemes, direct effects of attentional control on L2 were demonstrated not only for speech production but also for speech perception.

Conclusions:

The roles of attentional control and cross-language transfer on L2 speech are different for shared and unshared phonemes. Whereas L2 speech production of shared phonemes is also supported by cross-language transfer of L1, L2 speech perception and production of unshared phonemes benefit from attentional control only. This underscores the clinical importance of considering phonological overlap and supporting attentional control when assisting young sequential bilinguals' L2 development.
Tele-Ethics in Communication Disorders: Asking the Right Questions, Finding the Right Answers
Authors: Hall Kellyn Dailey
Published: January 2022

Purpose:

A hypothetical case is used to illustrate legal and ethical issues involving the decision to replace the traditional in-person service delivery model with telepractice in schools beyond the context of the initial COVID-19 health emergency. In this clinical focus article, the reader follows Maria, the lead speech-language pathologist (SLP) in the district, as she determines the feasibility of continuing telepractice in her district now that students and clinicians are returning to schools. First, she considers the support needed to implement this service delivery model within the school setting given the anticipated changes to the rules and regulations governing lawful and ethical provision of telepractice after the health emergency ends. Next, she decides if telepractice is warranted in the district by considering the rationales behind the requests. Faced with balancing school, student, and clinician needs, Maria uses an ethical decision-making model to determine if requests for telepractice, tied to health safety concerns and potentially influenced by implicit bias, reflect legal, ethical, and/or moral issues driven by fear or unconscious discriminatory motives.

Conclusions:

The health emergency gave SLPs working in schools the unique opportunity to experience the benefits and utility of telepractice. Following the return to schools, continuation of telepractice services will require support and training of SLPs. Many factors must be considered including equivalency of services, technology, and protection of privacy as they relate to the changes to the laws and regulations governing telepractice after the health emergency allowances end. Of primary importance is the selection of telepractice to address student needs, not to avoid specific schools because of their characteristics or location. An ethical decision-making model can be used as a framework to guide service delivery model decisions that balance the needs of the student, the clinician, and the district.
MIMO antenna for IOT devices with reconfigurable radiation pattern
Authors: Shin Hyunwoong , Kim Hyeongdong
Published: January 2022

Here, how to control isolation and correlation by adjusting the position of capacitors in a resonance structure in a MIMO ground radiation antenna is studied. The MIMO system consisting of two 7 mm × 7 mm printed ground radiation antennas operating at WLAN on a 40 mm × 40 mm ground plane was installed. If the positions of the capacitors of the two antennas are equally on the top of the ground plane, S12 is −5.2 dB and envelope correlation coefficient is 0.47. When the capacitors are orthogonal to each other, S12 is improved to −16.5 dB and envelope correlation coefficient is improved to 0.12. The orthogonality of the characteristic mode of the ground plane by the antennas is confirmed by the radiation patterns when the position of the capacitor is orthogonal.
Heuristic search for multi‐distance measuring equipment station selection
Authors: Liang Xiao , Milner Carl , Macabiau Christophe , Estival Philippe
Published: January 2022

To support alternative positioning, navigation and timing (A‐PNT), multi‐DME with better geometry than distance measuring equipment (DME)/DME can be used to improve the performance. Different from the existing station selection methods that have been proposed for DME/DME, a station selection method for multi‐DME should be considered in order to prevent unnecessary emission of navigation signals because DME receivers have limited number of channels and constrained real‐time processing power, and also to limit DME to GNSS L5/E5a interference. A heuristic algorithm is constructed to determine the quasi‐optimal selection of DME stations based on geometrical and computational cost restrictions, which is different from a brute‐force method checking all possible subsets and selecting the best one. A station selection method for multi‐DME is proposed based on the heuristic search. Meanwhile, the degradation of GNSS L5/E5a signal processing that is caused by DME signals is discussed. An advanced station selection method where the DME to GNSS signal interference is taken into account is also proposed. The experimental results show that the methods based on heuristic search can effectively select the quasi‐optimal subset of DME stations with less computational expense.
Prospective measures of control and prevention of Helminthosis among agricultural animals in animal complexes
Authors: Bayramgulova G.R. , Zulkarnaev A.B. , Muzafarov S.M. , Yagafarova G.A. , Aminev F.G.
Published: January 2022

Prospect of timely cleaning of livestock complexes from accumulated manure prevents environmental pollution. For this purpose, the most promising was the “cold” method of dehelminthization of a heap of manure, complete neutralization of chicken manure when heated and dried at temperatures above 100 °C, a “dry” method for neutralizing horse, pig, cow, sheep manure from helminth eggs using the Kranz biothermal method. For dehelminthization of humans and animals, science has recommended, and practice has successfully tested a fairly large, constantly growing and updated range of highly effective anthelmintics, mainly for gastrointestinal and partially for pulmonary helminthiasis.
Changes in the concentration of methane in the ecosystem in vitro against the background of Asteraceae family plants biomass
Authors: Sheida E.V. , Ryazanov V.A. , Denisenko K.S. , Shoshina O.V.
Published: January 2022

The assessment of Asteráceae Family Plants (rhizomes and roots of elecampane and wormwood) influence on the process of methane formation in the rumen ecosystem and metabolic processes was carried out. Studies (in vitro) were carried out using ANKOM Daisy II incubator (modifications D200 and D200I) according to a specialized method. Rumen contents were obtained from beef bulls with chronic rumen fistula. Gas analysis of air and volatile fatty acids samples was performed by gas chromatography. The results of the study showed that different dosages of phytobiotic preparations did not significantly affect the characteristics of fermentation in vitro. Phytobiotic preparations of elecampane and wormwood reduce the production of methane in the ruminal fluid, which may be associated with various active components or dosages of their administration.
Carbon balance of sandy loam soils in arid landscapes of the Chechen Republic
Authors: Gakaev Rustam
Published: January 2022

The spatial variability of the stability of soil aggregates and its relationship with runoff and soil erosion were studied in a semi-arid environment in the field in order to assess the validity of the stability of structures as an indicator of soil erosion in soils of sandy loam ridges. The influence of soil and relief properties on the variability of aggregate stability was also investigated. Significant relationships were found in the number of water droplets required to break down the aggregate, as well as the rate of runoff and erosion. The most significant correlation was found between the number of droplet impacts and the soil organic matter content. The stability of aggregates in the upper soil layer is apparently a valuable indicator of field runoff and inter-season soil erosion of sandy loamy ridges in semi-arid conditions.
Carbon capacity of gray forest soils in the Chechen Republic
Authors: Gakaev Rustam
Published: January 2022

Common areas of research needed to measure soil carbon include: (1) the impact of forest management, (2) the impact of climate change, and (3) the impact of increased carbon dioxide. The organic matter of the soil has a great influence on the productivity of the site due to its effect on the physical (bulk density, water retention capacity), biological (microbial populations) and chemical (cation exchange capacity) properties of soils. Recently, there have also been claims of the benefits of dead wood for forest ecosystems. However, as with all nutrients, too much carbon in the soil can have negative consequences, especially with regard to nitrogen immobilization.
Development of functional caramel using system packages MathLab
Authors: Berezhnov Nikolay Nikolaevich , Kurbanova Marina Gennadievna , Kolbina Anastasia Yurievna
Published: January 2022

The article presents substantiation for expanding the market for functional food products, in particular, confectionery - caramel. Proper nutrition is an integral part of a modern person diet; due to their properties, they increase the immunity and immune status of a person. The aim of the work is to create composite mixtures for sugar-free caramel using modern software. The studies were carried out using the MathLab software package, in particular the Statistica 10.0 software. A methodology for creating recipes using system packages has been developed. To enrich the caramel, the following components were selected: apple juice, coltsfoot extract, orange juice, mint and burdock extract, cranberry and lingonberry juices. An optimal recipe has been designed and equations are presented for calculating the dosages of the components of the enriched sugar-free caramel based on a natural sweetener isomalt with the addition of plant-based additives containing macro and micronutrients necessary for the normal functioning of the human body with a diagnosis of type II diabetes mellitus.
Mechanized Placement of Drip Tape in Potato Comb
Authors: Kizyaev Boris M. , Balabanov Victor I. , Martynova Natalia B.
Published: January 2022

Over the past two years, decrease in potato yield has been observed in the Moscow region. One of the main reasons is unfavorable weather conditions. To obtain a guaranteed yield, as well as to improve the quality of products, it is necessary to carry out reclamation works, including additional irrigation. Creation of the optimal water - air balance of the plant throughout the entire growing season will increase productivity, and improve the quality of agricultural products. Drip irrigation is the most economical method of irrigation, but its widespread use is hindered by the high proportion of manual labor when installing the drip tape. A mechanized method of laying the drip tape by placing the working equipment on the Grimme GF-75/4 comb former is offered. The existing methods for determining the irrigation rate do not consider the parameters of the humidification circuit, which leads to excessive irrigation and additional losses of irrigation water. The paper offers a method for determining the irrigation rate considering the shape of the humidification circuit and its geometric parameters.
Development of the pneumatic system with an annular aspiration channel for vibrating and rotation grain separator
Authors: Andreev Vasiliy L. , Shilin Vladimir V. , Ilichev Valeriy V. , Holodenina Tatjana S.
Published: January 2022

The pneumatic system with a vertical annular aspiration channel for vibration-centered grain separators been developed. The rational values of the disk grain distributor are the length of the sectors 0.15 m, the angle of inclination of the sectors 60°. The rotation speed of the distributor in the seed mode (grain supply 5…15 t/h) should be 100…200 min-1 and in the food mode (grain supply 15…25 t/h) must be 100…150 min-1. The effect of the release of light impurities in the developed aspiration system decreases from 45% to 20% with an increase in the supply of grain G from 5 to 25 t/h, herewith at the same time the loss of a full-fledged grain to waste decreases from 0.6...0.8% to 0.3...0.4%, while the effect of the release of light impurities in the aspiration system of the mass-produced vibration centrifugal grain separator decreases from 11% to 4% with the same losses of grain to waste.
Role of livestock in sustainable agriculture for food security
Authors: Karpova Maria V. , Roznina Nina V. , Esembekova Aliya U. , Shulgina Alla V. , Flakina Valentina M.
Published: January 2022

The livestock sector plays a special role in the formation of the rural economy and the life of society, performing a wide range of different functions. Agriculture, as a result of its activities, provides new jobs, in connection with which unemployment is reduced, there is also a decrease in rural migration, there is a change in the competitive environment, as a result of which the needs of the food market are being satisfied. A comprehensive assessment of the impact of animal husbandry on the development of the territory of the Kurgan region is the goal of our study. The article examines the development trends of the industry on the example of the Kurgan region. The influence of the development of animal husbandry on the provision of food security in the region has been studied. Such indicators as the volume of agricultural products for all types of categories, livestock, production of basic livestock products by categories of farms in the Kurgan region for 2016-2020 were considered and analyzed.
Strategic analysis on the integration of agricultural holding assets
Authors: Ogorodnikova Ekaterina , Khokholush Maria , Rostovtsev Konstantin
Published: January 2022

The topic of integration of agricultural and food enterprises into holdings, the strategy of their cooperation and integration is of great importance for the food security of the country. The article presents the results of a study of the integration of the agricultural holding Rusagro, based on the use of a matrix of dependence of the company's profitability indicators on its relative value in the market. Approbation of this method allows to reasonably make management decisions regarding the development of an agricultural holding.
A healthy eating plan for employees engaged in oil and gas exploration and production in the Far North
Authors: Vekovtsev Andrey , Vovk Elena , Poznyakovsky Valery , Tokhiriyon Boisjoni , Lapina Valentina
Published: January 2022

Proper nutrition is undoubtedly one of the most important factors of good health. Currently, the priority field of study for the Russian nutritionists is the development of well-balanced nutrition plans which can help to prevent or alleviate the most common medical conditions and work-related diseases. Extensive research has been carried out for the stateled program for the Development of Hydrocarbon Resources in the Northern Regions of Russia, including the Far North, where the huge oil and gas fields are located, and the specialists of Art-Life scientific production association have developed a healthy eating plan to help people working in the Far North maintain general well-being.
Study on resistance characteristics of submarine near water surface
Authors: Chen Jiabao , Lv Bangjun , Peng Likun , Huang Bin
Published: January 2022

The submarine is usually affected by free surface and the navigation resistance increases when sailing near the surface. In order to study the specific resistance characteristics of submarine sailing near the surface, the SUBOFF with appendages was taken as the research object, and the calculation model was built based on Star CCM+ fluid simulation software, and the resistance coefficients under different submarine depths and speeds were calculated. Through comparative analysis, the influence of the depth and speed of the submarine on the resistance components was obtained, and the cause of the formation was analyzed. The results show that the influence of the depth of submarine on friction resistance coefficient is small in general. With the increase of the depth of the submarine, the pressure resistance coefficient decreases, and the wave amplitude decreases. The shear wave of Kelvin wave system is more obvious and the effect of scattering is weakened, which is of great significance for the study of submarine concealment. With the increase of speed, friction resistance coefficient decreases, the overall change trend of pressure resistance coefficient is first increased and then decreases. The interference effect between free surface and hull increases first and then decreases at each depth. The wave shape changes and resistance results mutually confirm. The free surface mainly generates waves by interacting with the hull, which affects the resistance characteristics of the submarine. The interference effect is greatly affected by the depth and speed of the submarine.
An acoustic emission source localization approach based on time-reversal technology for additive manufacturing
Authors: Yang Xiaodi , Zhou Jiazhou , Gao Chunming , Zhang Ping , Liu Tingting , Zhang Kai , Zhang Changdong
Published: January 2022

The metal additive manufacturing process can inevitably lead to a great temperature gradient in the workpiece. Therefore, the thermal stress deformation and defects seriously affect the processing quality. In this paper, an array acoustic probe is designed on the base plate with the consideration of the time reversal technology. Corresponding simulations is implemented, which are designed to verify the ability of detecting and positioning the workpiece stress release acoustic emission signal. The simulation results demonstrate that the proposed method can position and monitor the random acoustic emission.
An effective hybrid search mode for multi-objective optimization with constraints
Authors: Chen Yujun , Yuan Wenqiang
Published: January 2022

In this paper a new search strategy for multi-objective optimization (MOO) with constraints is proposed based on a hybrid search mode (HSM). The search processes for feasible solutions and optimal solutions are executed in a mixed way for the existing methods. With regard to HSM, a hybrid search mode is proposed, which consists of two processes: Feasibility search mode (FSM) and optimal search mode (OSM). The executions of these two search modes are independent relatively and also adjusted according to the population distribution. In the early stage, FSM plays the leading role for exploring the feasible space since most of the individuals are infeasible. With the increase of the feasible individuals, OSM is the primary operation for the search of optimal individuals. The proposed method is simple to implement and need few extra parameter tuning. The handing method of constraints is tested on several multi-objective optimization problems with constraints. The remarkable results demonstrate its effectiveness and good performance.
Large-scale traffic flow simulation based on intelligent PSO
Authors: Liu Zeyu , Yang Gongping
Published: January 2022

With the rapid development of urban traffic, a large number of vehicles in cities not only bring convenience to people, but also bring a series of traffic problems, including traffic congestion and high traffic accident rates. Driving speed and waiting time of vehicles are two important factors of traffic problems. To simulate the real urban road traffic flow, a one-dimensional traffic flow grid model was proposed, which considered the nearest and next neighbour car at the same time, and connected the front and rear neighbour cars to optimize the traffic flow. The experiment results showed that our traffic flow grid model can simulate the real urban road traffic flow. In addition, we tried to optimize the urban traffic network model and improved the traffic speed of vehicles and reduced the waiting time.
Modeling method of combat mission based on OODA loop
Authors: Li Xiao , Liu Desheng
Published: January 2022

Today, modern warfare has shifted from weapon-centric operations to network-centric system operations, which has led to a linear increase in the complexity of combat missions. When a commander faces a high-level mission, how to model the entire combat mission is a critical step, and it is also the basis for the generation of subsequent combat plans and combat command and control. Aiming at this problem, this paper proposes a task modeling method based on the OODA loop. This method first decomposes the mission task, and defines four meta tasks based on the OODA loop theory, and finally analyzes the meta tasks from the perspective of time and information. The mission relationship is defined, which can realize the modeling and formal description of the entire combat mission process, and provide support for the follow-up combat links.
Investigation of ecological environment and assessment of ecological security in Tieshan Reservoir watershed
Authors: Wang Na , Wang Ying , Liu Zhan
Published: January 2022

In this study, based on the “Driver-Pressure-State-Impact-Response” (DPSIR) assessment model, an assessment index system aming at the Tieshan Reservoir watershed was established from 4 aspects including social-economic impact, ecological subsystem, ecological service subsystem, regulation and management. Eighteen major items containing 55 indexes were selected in the assessment index system. Furthermore, the ecological security index (ESI) was calculated, and the deviation degree of reservoir ecological safety from the standard state was assessed. Results showed that ecological security index of Tieshan Reservoir watershed is 89, ecological security level is I , indicating security. The low security indexes of total phosphorus and total nitrogen were the major disadvantage factors that affected the ecological security of Tieshan Reservoir watershed, including rural life pollution and farmland runoff pollution. In addition, long-term mechanism of protection and development has not been formed yet, which also restricts the economic growth. Strengthening the formulation of laws and regulations on environmental protection, tamping the basic capacity building of water pollution control, developing ecological agriculture and green tourism are the important ways to improve the ecological security and realize the sustainable development of Tieshan Reservoir watershed.
Research on the integration of curriculum ideological and political education, innovation and entrepreneurship education into professional curriculum system in higher vocational colleges under the new engineering background
Authors: Dong Xiangli
Published: January 2022

Under the background of new engineering, the traditional curriculum can no longer meet the purpose of talent training in higher vocational colleges. The curriculum system, curriculum resources, teaching staff, etc. need to be improved, especially the curriculum system should keep pace with The Times. This paper mainly studies the integration of Curriculum ideological and political education, Innovation and entrepreneurship education into the construction of professional curriculum system in higher vocational colleges under the background of new engineering. It mainly includes the overall framework, basic content and research value of the research. It also has reference value for other related majors. It plays an important demonstration and radiation role in the integration of subjects in school and the extension of influence outside school, and steadily improves the construction and teaching quality of professional courses in higher vocational colleges.
Dynamic model of macro crowd merging based on abnormal pedestrian posture
Authors: Zhao Rongyong , Jia Ping , Wang Yan , Li Cuiling , Han Chuanfeng , Zhang Zhishu
Published: January 2022

Crowd merging is a complex process, and any sudden external or internal disturbance will destroy the stability of the crowd. The occurrence of abnormal behavior will affect the crowd flow process and inevitably affect the stability of the crowd flow system. The position information of the joint points is obtained through the OpenPose algorithm, and the kinematics characteristics of each node are studied. It is judged whether the number of pedestrians in the crowd and the scale of the building scene are greater than the empirical setting value based on engineering statistical data and expert experience. When the number of pedestrians is more than 2,000 and the total area of the passage is more than 2,000 square meters, the appropriate macro-dynamic model is selected. The Aw-Rascle (AR) fluid dynamics model is selected in this study. The joint point information obtained through the OpenPose is combined with the macroscopic fluid dynamics model to construct a macroscopic crowd flow dynamics model based on the pedestrian's abnormal posture.
Music emotion recognition algorithm based on BP neural network
Authors: Liu Xu , Ge Pingxiao
Published: January 2022

Music plays a very important role in animation production. Because it could better express the emotion of the character, this paper uses BP neural network to identify the music emotion. This paper first introduced the structure of BP neural network. Then, the parameters and structure of the network were designed according to the category of music emotion. Finally, a three-layer BP neural network with 5 input nodes, 13 hidden layer nodes and 4 output nodes was constructed and applied to music emotion recognition. The recognition accuracy was 85.02%, which basically met the requirements of music emotion recognition and achieves the expected effect.
Research on cyber security risk of telematics box in intelligent connected vehicle
Authors: Ma Chao , Zhao Hao , Wang Tong
Published: January 2022

With the rapid development of the automotive industry and the wide application of 5G network technology, there are more and more Telematics Box (T-Box) equipped with intelligent operating systems in vehicles and they are becoming more and more complex. Because it is connected to the on-board CAN bus internally and interconnects with mobile phone /PC through the cloud platform externally, the security of T-Box must be fully guaranteed, to make the automotive more secure. T-Box can realize remote control function, so the T-Box information security problem has been paid more and more attention. In this paper, the T-Box were tested from multiple dimensions by using various methods, and the results were statistically analyzed, and the corresponding protection strategies were proposed for the corresponding security risks.
New human-computer interaction regulations for ship safe driving based on multi-mode data interconnection
Authors: Yang Yi , Chen Lixing , He Pengfei , Lin Xingzhi
Published: January 2022

Based on the analysis of the multi-mode data of ship mechatronics and the new human-computer interaction regulations for safety driving, a new safety driving regulation based on multi-mode data is put forward. The new regulations for ship safe driving use mechanical and electrical data to form small-world data interconnection. Artificial intelligence and human-computer interaction operation information are used to integrate and communicate, and human-computer interaction data are incorporated to standardize driving behavior to integrate historical driving data, and finally, the standardized automatic self-driving is formed. The new human-computer interaction regulations formed by the safe driving system make it possible to solve and optimize the ship safe driving mode.
Research on intelligent diagnostic techniques for rolling bearings based on unbalanced data sets
Authors: Xing Zhikai , Liu Yongbao , Wang Qiang , Li Jun
Published: January 2022

In this paper, based on the combination of comprehensive sampling and one-dimensional convolutional neural network, a bearing fault intelligent diagnosis technique is proposed for the classification of rolling bearing vibration data. At first, the fault data set is expanded by ADASYN method. Then, the data is cleaned up by Tomek link under sampling technique, the risk of overfitting caused by overlap of different classes is reduced and the data of different categories is more apparent, and finally the normal data set and fault data set after comprehensive sampling are classified by one-dimensional convolutional neural network algorithm. Compared with random forests and support vector machines, the results show that the method has a high accuracy in identifying classifications and can effectively solve the classification problem of unbalanced bearing data.
The research of EEG feature extraction and classification for subjects with different organizational commitment
Authors: Zhang Rui , Wang Ziyang , Liu Yu
Published: January 2022

With the development of EEG analysis technology, researchers have gradually explored the correlation between personality trait (such as Big Five personality) and EEG. However, there are still many challenges in model construction. In this paper, we tried to classify the people with different organizational commitment personality trait through EEG. Firstly, we organized the participants to complete the organizational commitment questionnaire and recorded their resting state EEG. We divided 10 subjects into two classes (positive and negative) according to the questionnaire scores. Then, various EEG features including power spectral density, microstate, functional brain network and nonlinear features from segmented EEG sample were extracted as the input of different machine learning classifiers. Next, several evaluation metrics were used to evaluate the results of the cross-validation experiment. Finally, the results show that the EEG power in α band, the weighted clustering coefficient of functional brain network and the Permutation Entropy of EEG are relatively good features for this classification task. Furthermore, the highest classification accuracy rate can reach 79.9% with 0.87 AUC (the area under the ROC). The attempts in this paper may serve as the basis for our future research.
Practical tracking control of piezoelectric actuators with time-delay estimation and nonsingular terminal sliding mode
Authors: Lin Haiping , Gu Hanlie , Ma Jinyu , Yu Shengdong
Published: January 2022

A novel type of nonlinear robust control strategy is proposed in view of uncertain nonlinear factors, such as hysteresis, creep, and high-frequency vibration, of piezoelectric actuators (PEAs). This strategy can be used for the precise trajectory tracking of PEAs. The Bouc–Wen dynamic model is reasonably simplified to facilitate engineering application. The hysteresis term is summarized as an unknown term to avoid its nonlinear parameter identification. The controller robustness is achieved due to the nonsingular terminal sliding mode control, and the online estimation of unknown disturbances is realized because of the delay estimation technology; thus, no prior knowledge of the unknown boundary of the system is required. The precision robust differentiator is used to estimate the speed and acceleration signals in real time on the basis of the obtained displacement signals. The closed-loop stability of the system is proved by the Lyapunov criterion. Experimental results show that the proposed control strategy performs better than the traditional time-delay estimation control in terms of control accuracy and energy conservation. Therefore, the proposed control strategy can play an important role in the micro/nanofield driven by PEAs.
La cohérence temporelle en optique classique
Authors: Chavel Pierre
Published: January 2022

Déterminante pour l’observation d’interférences, la cohérence temporelle est souvent reliée à la comparaison entre différence de marche et longueur de « train d’onde ». Un examen plus détaillé fait ressortir les concepts les plus pertinents : l’autocorrélation du champ et le bruit classique de détection.
Entre injonction et auto-régulation : le cas de la Fédération suisse de patinage dans la mise en œuvre d’une politique de la formation
Authors: Reveilhac Maud
Published: January 2022

Cette étude de cas illustre la façon dont la Fédération suisse de patinage (SIS) a progressivement intégré la politique de formation édictée par le gouvernement via l’organisation faîtière du sport, Swiss Olympic. Prenant appui sur la littérature relative à la professionnalisation et l’autorégulation des fédérations face aux injonctions gouvernementales, cette étude se focalise sur les dimensions de la professionnalisation mises à contribution pour l’adaptation de SIS à la politique de la formation. Cette analyse repose sur une approche managériale à travers le modèle des 7S de McKinsey. Elle s’étend également aux parties prenantes de SIS en vue de faire ressortir les difficultés rencontrées par SIS dans la mise en œuvre de la politique de la formation pour le patinage artistique. Les entretiens menés et l’analyse de la documentation à disposition montrent comment la politique de la formation visant à garantir l’unité du suivi national est devenue l’une des principales préoccupations stratégiques de SIS entraînant des changements importants au niveau de ses structures et de son personnel, mais également au niveau du style de leadership. Les principales difficultés rencontrées par SIS sont liées à la conciliation de différentes logiques de la pratique sportive et à la coordination de plusieurs parties prenantes. Cette étude revêt de l’intérêt au-delà du contexte helvétique, notamment pour comprendre l’évolution des fédérations sportives en lien avec les politiques gouvernementales.
Lichttherapie zur Delirprävention bei Intensivpatienten: Was sagt die Evidenz?
Authors: Schmidt Sebastian , Hancke Laura , Spies Claudia , Piazena Helmut , Luetz Alawi
Published: January 2022

Die zirkadiane Dysrhythmie betrifft die Mehrzahl der Intensivpatienten und hat weitreichende Auswirkungen auf Organfunktionen. Auf der Ebene des zentralen Nervensystems werden kognitive Exekutivfunktionen beeinträchtigt und die Entwicklung eines Delirs gefördert. Aus diesem Grund sollten mehrdimensionale, patientenindividualisierte chronotherapeutische Konzepte für die Intensivmedizin entwickelt werden. Die zirkadiane Lichttherapie ist in diesem Kontext ein vielversprechender Ansatz.
Konzepte zur Reduktion der Lärmbelastung auf der Intensivstation
Authors: Theuerkauf Nils-Ulrich , Putensen Christian , Schewe Jens-Christian
Published: January 2022

Die Lärmbelastung auf der Intensivstation ist ein allgegenwärtiges, erhebliches Problem für Patienten und Personal. Viele maßgebliche Lärmquellen sind mitverantwortlich für die häufigen Schlafstörungen der Patienten, die das Auftreten eines Delirs begünstigen. Der Beitrag fasst die aktuelle Evidenz zur Entstehung lärmassoziierter Auswirkungen zusammen und zeigt Optionen zur Lärmreduktion und Verbesserung der Therapie von Intensivpatienten auf.
Sulpirid induzierte Dystonie bei einem Patienten mit Tourette-Syndrom
- eine Schlaganfall ähnliche Präsentation
Authors: Abdelnaby Ramy , Abosrea Mona Ali , Schönfeldt-Lecuona Carlos , Rudek Markus A. , Elsayed Mohamed
Published: January 2022

Wir berichten über den Fall einer Sulpirid-induzierten Dystonie bei einem
Patienten mit einem bekannten Tourette Syndrom. Aufgrund des plötzlichen
Auftretens einer schlaganfallähnlichen Symptomatik während einer
körperlichen Belastung war die eigentliche Dystoniediagnose erschwert.
Nach Ausschluss einer vaskulären Ursache (Blutung,
Gefäßdissektion, etc.) durch geeigneter Bildgebung wurde
Biperiden infundiert, welche zum sofortigen Verschwinden der Dystonie
führte.