bluuebunny/crossref_metadata_2025 huggingface dataset:
Entre a fantasia e a ação: as patologias sexuais na web
Authors: Silva Renata Almeida de Souza Aranha e , Baltieri Danilo Antonio
Published: March 2023

O acesso à rede mundial de computadores possibilitou que as relações virtuais acontecessem de uma maneira menos compromissada com a realidade e favoreceu a aceitação de práticas sexuais incomuns ou consideradas inadequadas. Atualmente, várias plataformas comunicacionais são alimentadas por usuários, responsáveis por conteúdos que criam interações, troca de materiais e relacionamentos online. Pode-se considerar que a democratização da sexualidade em ambientes virtuais tenha benefícios; porém, o excesso de informação sem critérios e a facilidade de acesso a fotos, vídeos e outros materiais pode causar danos. É possível observar espaços para a divulgação de fantasias parafílicas, entre elas a zoofilia (excitação ou práticas sexualmente excitantes envolvendo animais), que, do ponto de vista médico, é um transtorno de preferência sexual ainda pouco estudado. Estabelecer limites para relacionamentos mediados pela Internet e avaliar a consequência dessa interação na prática não é tarefa fácil, mas necessária.
O papel dos hormônios na psicopatia
Authors: Barros Alcina Juliana Soares , Taborda José Geraldo Vernet , Rosa Regis Goulart
Published: March 2023

Os hormônios desempenham um importante papel para a compreensão das bases biológicas da psicopatia e do transtorno de personalidade antissocial. Os sistemas hormonais podem ser influenciados por fatores genéticos e ambientais e, em consequência, atuar no funcionamento cerebral. Como marcadores biológicos, os hormônios podem fornecer pistas esclarecedoras sobre o que ocorre no cérebro de um psicopata. Os dois hormônios mais implicados até o momento na psicopatia, com seus respectivos eixos, são o cortisol e a testosterona. Este artigo visa correlacionar as manifestações cognitivas, emocionais e comportamentais da personalidade psicopática com os desequilíbrios neuroendócrinos.
Due Diligence and the Protection of the Marine Environment
Authors:   Korea International Law Review, Lim Jeonghee
Published: March 2023

The Part XII of the UNCLOS, entitled “Protection and Preservation of the Marine Environment,” is by nature a framework and does not contain detailed norms and contents. Therefore, the role of due diligence in understanding and implementing marine environmental protection is critical. Due diligence can fill the gap in the content of specific obligations, serve as a criteria for fulfilling the obligation to protect the marine environment, and act as a factor to strengthen such obligation.
With regard to the obligation to protect the marine environment, considering it merely element for determining breach of the obligations in the context of “State responsibility” has a limitation. Because the nature of the marine environment protection obligation requires the prevention of the pollution or harm to the marine environment. Given the nature of the primary obligation, due diligence can perform the function to bridge the gap between primary and secondary obligations. As due diligence is a flexible and variable concept, states can strengthen obligations to protect the marine environment and prevent marine pollution by reflecting the higher standards enabled by technological development.
However, there is a concern that the flexible nature of this concept allows countries to have broader discretion in fulfilling obligations. This is because there is room for countries to interpret the degree of their obligations differently due to the subjective characteristics of expressions such as “all appropriate,” “as much as possible,” “necessary,” and “effective.” Recognizing these limitations, it would be desirable to enforce compliance with the proceduralization of the due diligence obligations. This includes developing each procedural obligation for the protection of marine environment and defining the forms and criteria of the due diligence obligation within the context of each procedural obligation. By doing so, countries can ensure that due diligence is implemented consistently and effectively in protecting the marine environment.
NMDARs regulate the excitatory-inhibitory balance within neural circuits
Authors: Zhou Liang , Sun Xiaohui , Duan Jingjing
Published: March 2023

Excitatory-inhibitory (E/I) balance is essential for normal neural development, behavior and cognition. E/I imbalance leads to a variety of neurological disorders, such as autism and schizophrenia. NMDA receptors (NMDARs) regulate AMPAR-mediated excitatory and GABAAR-mediated inhibitory synaptic transmission, suggesting that NMDARs play an important role in the establishment and maintenance of the E/I balance. In this review, we briefly introduced NMDARs, AMPARs and GABAARs, summarized the current studies on E/I balance mediated by NMDARs, and discussed the current advances in NMDAR-mediated AMPAR and GABAAR development. Specifically, we analyzed the role of NMDAR subunits in the establishment and maintenance of E/I balance, which may provide new therapeutic strategies for the recovery of E/I imbalance in neurological disorders.
Substrate stiffness in nerve cells
Authors: Si Weijin , Gong Jihong , Yang Xiaofei
Published: March 2023

Recently, substrate stiffness has been involved in the physiology and pathology of the nervous system. However, the role and function of substrate stiffness remain unclear. Here, we review known effects of substrate stiffness on nerve cell morphology and function in the central and peripheral nervous systems and their involvement in pathology. We hope this review will clarify the research status of substrate stiffness in nerve cells and neurological disorder.
Activatable molecular fluorescence probes for the imaging and detection of ischemic stroke
Authors: Wang Mengdie , Zhang Yan
Published: March 2023

The real-time, noninvasive, nonionizing, high spatiotemporal resolution, and flexibility characteristics of molecular fluorescence imaging provide a uniquely powerful approach to imaging and monitoring the physiology and pathophysiology of ischemic stroke. Currently, various fluorescence probes have been synthesized with the aim of improving quantitative and quantitative studies of the pathologic processes of ischemic stroke in living animals. In this review, we present an overview of current activatable fluorescence probes for the imaging and diagnosis of ischemic stroke in animal models. We categorize the probes based on their activatable signals from the biomarkers associated with ischemic stroke, and we present representative examples of their functional mechanisms. Finally, we briefly discuss future perspectives in this field.
Эстетическая абдоминопластика- это не коррекция фигуры, a забота о здоровье и красоте
Authors: Rustamova A.B.
Published: March 2023

Одной из отраслей медицины в наше время является эстетическая абдоминопластика – косметическая хирургия. Врачи знакомят широкие слои населения с тем, как беречь здоровье, избегать болезней, разъясняют, почему необходимо строго соблюдать режим дня, культуру питания. Косметические салоны, процедурные SPA, походы к пластическому хирургу в прошлом были доступны только для избранных, которые видели в своей красоте ключ к успеху в обществе и обогащению. В наше время косметическая хирургия перестала быть привилегией избранных и становится доступной для всех женщин, независимо от их возраста и занимаемой или местом в обществе. Необходимо, чтобы женщина критически относилась к эстетическим недостаткам своей внешности. Что же касается остального, то у нее есть все возможности устранить эти недостатки, ведь советы врачей хирургов-пластиков, диетологов, спорт – это доступно каждому. Нужно только иметь волю и жажду быть красивой.
Cərrahi Xəstəliklərin Diaqnostika Və Müalicəsində Yeni Üsullar" Beynəlxalq Konfrans Tezis Toplusu
Authors: Azerbaijan Medical University
Published: March 2023

III Cərrahi xəstəliklər kafedrasının 100 illiyinə həsr olunmuş "Cərrahi xəstəliklərin diaqnostika və müalicəsində yeni üsullar" Beynəlxalq Konfrans ATU-nun Tədris Cərrahi Klinikasının konfrans zalında keçiriləcəkdir. Konfransda Azərbaycan, Türkiyə, Rusiya və digər ölkələrdən aparıcı cərrahi mərkəzlərin mütəxəssislərinin iştirakı nəzərdə tutulubdur.
الـمَنْفَى في شِعر أحمَد شَوقي ومحمَّد عاكِف أرصوي: انعكاسات من الشوقيات والصفحات
Authors: ALY Emad A. Abdelbaky , DOĞRU İhsan
Published: March 2023

المنفى مِن الآلام التي عاشها النَّاس، وقد استمر هذا الوضع غير المرغوب فيه عَلى مرِّ العصور وأَضحى قدرًا للبعض مُنذ المنفى الأوّل الذي عاشه سيدنا آدم -عليه السلام- عند خروجه مِن الجنة إلى الدنيا. ومِن المعروف –عبر التاريخ- أنَّ بعض الأدباء تعرّضوا لمغادرة أوطانهم، أحيانًا من يخالف حكّام الدولة يُعاقَب بالإعدام ويُقتَل وهي عقوبة أَشد مِن المنفى، إلا أنَّ الحكّام الذين لا يريدون إعدام أعدائهم يُفضِّلون قَطع الصِّلة بين المعارضين وبين شعبهم وأوطانهم مما يُقلِّل نفوذهم، خاصة مع بِداية مرحلة الاستِعمار في الشَّرق الأوسط لوحِظ أنَّ المنفى أصبح مَصيرًا محتومًا، وبسبب النّزاعات بين المستعمرين ورجال الدَّولة أَحيانًا أو المستعمرين والمقرِّبين منهم في أحيانٍ أخرى تم نفي رجال الدولة والشُّعراء والكتَّاب إلى أماكن معينة، وهكذا تَعرَّض العديد مِن الشعراء والأدباء سواء العرب أو الأتراك للمَنفى، والشَّاعران أحمد شوقي ومحمد عاكف أرصوي أيضًا اللذان عاشا في الفترة الزمنية نفسها مِن الشُّعراء الذين تعرضوا للمَنفى، حيث عاش أحمد شوقي في المنفى في إسبانيا خلال سنوات الحرب العالميَّة الأولى بناءً على أمر البريطانيين، أمَّا محمد عاكف أرصوي فقد عاش منفاه في مصر بين عامي 1925 – 1936. على أنَّ محمد عاكف أرصوي لم ينف بناء على أمرٍ رسميٍّ من إدارة الدولة إلا أنّه أُجبِر على الذهاب إلى مصر بسبب فكره المخالف وتعرّضه للاضطهاد. وهكذا في دراستنا هذه يتم إلقاء الضّوء على كيفية التعامل مع مَفهوم المنفى في ديوان الشَّاعرين؛ ونِقاط الالتقاء والاختلاف بينهما، من خلال تَتبُّع ما كتب في ديوان (الشّوقيات) وديوان (الصفحات). على أنّ الدراسة قد اقتصرت على الأبيات المتعلَّقة بالمنفى.
Cenap Şahabettin’in Son Gezi Yazıları Âfâk-ı Irak’ın Unutulmuş Şehirleri: Necef ve Kerbela
Authors: ÖZBEK Seda
Published: March 2023

Servet-i Fünûn’un önde gelen yazarlarından olan Cenap Şahabettin sadece şiirleriyle değil nesirleriyle de Türk edebiyatında önemli bir yer edinmiştir. Nesir alanında özellikle gezi yazılarıyla anılan yazarın seyahatname türüne katkıları dikkate değerdir. Çeşitli gazete ve dergilerde yayımladığı gezi yazılarının bazılarını (Hac Yolunda, Avrupa Mektupları) sağlığında kitaplaştırmış, tefrika halinde gazete sütunlarında kalan bazı seyahat yazıları ise (Âfâk-ı Irak, Suriye Mektupları) araştırmacılar tarafından sonradan kitaplaştırılmıştır. Bunlardan Tasvir-i Efkâr gazetesinde 7 Haziran 1914 - 18 Mart 1916 tarihleri arasında on üç sayıda yayımlanan Âfâk-ı Irak adlı yazı dizisi Bülent Yorulmaz tarafından Latin harflerine aktarılarak Âfâk-ı Irak Kızıldeniz’den Bağdat’a Hatıralar adıyla 2002 yılında kitap halinde yayımlanmıştır. Bülent Yorulmaz incelemesinde Âfâk-ı Irak yazı dizisinin bitmemiş hissi verdiğine ve devamı konusunda herhangi bir bilgiye sahip olmadığına dikkat çekmektedir. Hakikaten Âfâk-ı Irak 13. tefrikada yarım kalmış izlenimi vermektedir. Nitekim bu izlenim sebepsiz yere değildir. Kızıldeniz’de başlayıp Bağdat’ta noktalandığı sanılan bu seyahatnamede Irak ufuklarının ardında kalan ve hâlâ görülmeyi bekleyen Necef ve Kerbelâ da vardır. 1919 yılında Servet-i Fünûn dergisinde “hatıra-i seyahat” üst başlığı ile yayımlanan Necef-i Eşref ve devamında tefrika halinde yayımlanan Sahrâ-yı Kerbelâ ve Kerbelâ adlı makaleler Cenap Şahabettin’in Âfâk-ı Irak adlı seyahat hatıralarının son metinleridir. Bu makalede genel hatlarıyla Âfâk-ı Irak hakkında bilgi verilmiş ve adı geçen metinlerin Âfâk-ı Irak’ın devam metinleri olduğu üzerinde durulmuştur. Söz konusu metinler Latin harflerine aktarılarak gerek Cenap Şahabettin külliyatına gerek Türk seyahat edebiyatına katkı sağlamak amaçlanmıştır.
Comparison of Regression Algorithms to Predict Average Air Temperature
Authors: PARLAK Berke Oğulcan , YAVAŞOĞLU Hüseyin Ayhan
Published: March 2023

Regression algorithms are statistical techniques used to predict the value of a dependent variable, based on one or more independent variables. These algorithms are commonly used in fields such as economics, finance, and engineering. Temperature prediction is a specific application of regression analysis. In this case, the dependent variable is temperature and the independent variables include factors such as humidity, speed of the wind, direction of the wind, and precipitation. There are many different types of regression algorithms, each with its strengths and weaknesses. The study compares the performance of multiple regression models in predicting the average air temperature, using one month's weather data for the Beşiktaş district of Istanbul. A total of 6 different regression models, including ridge, lasso, linear, polynomial, random forest (RF), and support vector (SV) regressions, were included in the study. Among the regression models trained and tested on two different data sets, the three most successful models in predicting average air temperature were lasso, RF, and polynomial regressions (PRs), respectively.
Non-Invasive Bio-Signal Data Classification Of Psychiatric Mood Disorders Using Modified CNN and VGG16
Authors: URAL Ali Berkan
Published: March 2023

In this study, the aim is to develop an ensemble machine learning (ML) based deep learning (DL) model classifiers to detect and compare one type of major psychiatric disorders of mood disorders (Depressive and Bipolar disorders) using Electroencephalography (EEG). The diverse and multiple non-invasive biosignals were collected retrospectively according to the granted ethical permission. The experimental part is consisted from three main parts. First part is the data collection&development, the second part is data transformation and augmentation via Spectrogram image conversion process and online Keras data augmentation part, respectively. The third and final part is to fed these image dataset into modified Convolutional Neural Network (CNN) and VGG16 models for training and testing parts to detect, compare and discriminate mood disorders types in detail with a specific healthy group. As the performance evaluation background of the mood disorder classification models, confusion matrices and receiver operating characteristics (ROC) curves were used and finally, the accuracy achieved by CNN model was 88% and VGG16 model was %90, which is an improvement of 10% compared to the previous studies in literature. Therefore, our system can help clinicians and researchers to manage, diagnose and prognosis of the mental health of people.
G-20 Ülkelerinin Yeşil Merkez Bankacılığı Karnelerine Göre Değerlendirilmesi / Evaluation of Countries According to Green Central Banking Scorecards
Authors: AKÇAKANAT Özen , AKSOY Esra
Published: March 2023

Bu çalışmanın amacı, G-20 Ülkelerinin Positive Money araştırma organizasyonu tarafından oluşturulan Yeşil Merkez Bankacılığı verileri ile sıralamasını yapmaktır. Yeşil Merkez Bankacılığı kapsamında G-20 ülkelerinin iklim ile mücadele için dört kategoride bilgileri toplanarak her ülke için karne puanı oluşturulmaktadır. Bu kategoriler “Araştırma ve Savunuculuk”, “Para Politikası”, “Finans Politikası” ve “Örnek Liderlik”tir. Çalışmada G-20 ülkelerinin Yeşil Merkez Bankacılık performansları bu kategorilerle değerlendirilmektedir. Analiz için Çok Kriterli Karar Verme yöntemlerinden biri olan PSI yöntemi tercih edilmiştir. PSI yöntemi birçok alternatif ve kriteri eş zamanlı analiz ederek çözüme ulaştıran yöntemlerden biridir. Analiz sonuçlarına göre ilk iki sırada, Fransa ve Brezilya çıkmıştır. İlk sıralarda çıkan ülkelerin merkez bankalarının iklim değişikliği konusunda daha hassas ve aktif oldukları görülmektedir. Sonuç olarak G-20 ülkeleri merkez bankalarının iklim değişikliğiyle faaliyet boyutları belirlenmektedir. Bununla birlikte çalışmada G-20 ülkelerinin merkez bankalarının iklim değişikliği konusunda ne kadar aktif olduğu ve diğer ülkeler içerisinde hangi konumda olduğu belirlenerek farkındalık oluşturulmak istenmiştir.
Viruses of the Filoviridae family
Authors: Chernykh A. , Hancharou A.
Published: March 2023

The article considers representatives of the Filoviridae family, some of which are the causative agents of hemorrhagic fever, which is fatal to humans. The current state of development of immunobiological drugs for the treatment and medical prevention of diseases caused by filoviruses has been analyzed.
Smallpox and monkeypox: characterization of viruses and prevention of infections
Authors: Babrukevich D. , Hancharou A. , Antonevich N. , Bogdan V.
Published: March 2023

This review addresses the poxviruses which are the most dangerous and urgent biological threats, especially smallpox and monkeypox. The authors discuss general characteristics of viruses, historical aspects of diseases caused by these pathogens, vaccination and control and treatment of viral infections.
Artificial intelligence technologies in monitoring pathomorphological changes in the central nervous system in multiple sclerosis
Authors: Fedulov A. , Karapetyan G. , Kosik I. , Borisov A. , Blagochinnaya K. , Volkova N.
Published: March 2023

The paper presents one of the options for automating the evaluation procedures of magnetic resonance imaging (MRI) of the brain in patients suffering from one of the most severe diseases of the central nervous system (CNS), multiple sclerosis.
Evaluation of environment through DREEM by medical students with preferred learning styles in a Private Medical College of Pakistan.
Authors: Syeda Hanaa Fatima  , Sajida Naseem  , Syed Shoaib Hussain Shah  , Syeda Sanaa Fatima
Published: March 2023

Objective: To identify how students with the preferred learning styles rate the academic environment of the Medical College. Study Design: Cross-sectional study. Setting: Shifa College of Medicine, Shifa Tameer-e-Millat University. Period: April 2022 to September 2022. Material & Methods: After taking ethical approval from the ethical review board of the institute, a two hours slot was designated in the schedule of students of five years in the private medical college. Students were given two questionnaire, Honey & Mumford LSQ and DREEM. Students were requested to leave the demographic part in order to maintain confidentiality of data. Data analysis was done and the preferred learning style of the cohort was found. DREEM questionnaires of these students were also analyzed in order to find their ratings of the environment. Results: Preferred learning style of the cohort was Reflectors (58.4%). Reflectors marked domains of DREEM as, A more Positive Approach, Moving in the right Direction, Feeling More on the Positive Side, A more Positive Atmosphere and Not too bad. Conclusion: Environment of the medical college seemed fit for the students with preferred learning style (Reflector). Further studies are indicated to rate the environment from students with other learning styles.
DIFICULDADES NA APRENDIZAGEM DE TRIGONOMETRIA, SOB A ÓTICA DOCENTE
Authors: SILVA CLAUDIO LIMA DA , SILVA ANA KELY MARTINS DA , Santos Maria de Lourdes Silva
Published: March 2023

RESUMO
Apresentamos os resultados de uma pesquisa, intencionando responder a seguinte problemática:
quais as dificuldades apresentadas pelos alunos do 2º ano do Ensino Médio na aprendizagem de
trigonometria, segundo os professores? Para tanto, teve como objetivo identificar as dificuldades de
aprendizagem dos alunos do 2º ano do Ensino Médio no estudo de trigonometria, segundo a
percepção docente. Foram consultados 53 docentes de matemática, utilizando um formulário
eletrônico google forms. A análise ocorreu de forma qualitativa, a partir das respostas dos professores
consultados. Os resultados indicam que as maiores dificuldades dos alunos são inerentes a
compreensão dos conceitos matemáticos e na resolução de problemas. Constatamos que o ensino
de trigonometria está dissociado da realidade do estudante, e que os professores raramente abordam
o seu contexto histórico. Concluímos que se faz necessário maior investimento na educação, por
meio da aquisição de recursos pedagógicos e oferta de efetiva formação inicial e continuada aos
professores.
Palavras-chave: Dificuldades; Ensino; Aprendizagem; Matemática; Trigonometria.
Doenças Infecciosas Parasitárias - Edição III
Authors: MORAES CHARLYSON SALES
Published: March 2023

O livro Doenças Infecciosas e Parasitárias reúne aspectos da prevenção, diagnóstico e manejo de doenças infecciosas e sexualmente transmissíveis em humanos e animais, bem como genética molecular, fisiopatologia e epidemiologia. O Brasil é considerado um local endêmico para várias dessas doenças como dengue, chikungunya, malária, doenças de Chagas entre outras. Os casos de doenças sexualmente transmissíveis ainda continuam crescendo, o que deve ser alerta para serviços públicos de saúde. Reunir trabalhos de qualidade na área é a proposta da Editora Pasteur e isso foi obtido com êxito nesta primeira edição. Acadêmicos, profissionais e pesquisadores da área assinam suas contribuições através dos capítulos publicados e esperam que o leitor tenha uma agradável experiência com seus estudos. Esperamos ansiosos pelas próximas edições!
An interview with Marisa Michelini: IUPAP-ICPE medal, professor of physics-education research at Udine University, GIREP President
Authors: Chiofalo Maria Luisa Marilù , Michelini Marisa
Published: March 2023

The present interview was conceived and realized for the occasion of the first 45 years of endless Physics Education Research activity of Professor Marisa Michelini, a lifetime dedicated to innovate teaching and learning environments to all degrees of instruction, and to design institutional architectures, where rooting these innovations. The interview structure is inspired to the nature of scientific thinking, i.e. inducing more general understanding from concrete observations, in two manners. First, the interview focuses on (ten) topics drawing from three box-cases about physics education research and teachers education in scientific areas: innovations in teaching/learning environments; theoretical and methodological frameworks; and strategies and tools for institutional cooperation between schools and governing bodies to urge policy making. Each topic is introduced by observations, from which the interview questions are induced. Second, each question draws from Marisa Michelini’s contributions, to touch core topics at the heart of science education, science and society.
Cost, Footprint, and Reliability Implications of Deploying Hydrogen in Off-grid Electric Vehicle Charging Stations: A GIS-assisted Study for Riyadh, Saudi Arabia
Authors: Elshurafa Amro , Muhsen Abdelrahman , Felder Frank
Published: March 2023

We quantify the cost, footprint and reliability implications of using hydrogen in off-grid electric vehicle charging stations (CS) using an optimization model coupled with a geographical information system (GIS) analysis for the city of Riyadh, Saudi Arabia. We also account for the challenges associated with wind energy deployment as a generation technology for CS within city centers.
Spatial Modeling of Bargaining Among Stakeholders in Energy Policy: The Case of Japanese Nuclear Plants
Authors: Hatipoglu Emre , Efird Brian , Al Muhanna Saleh
Published: March 2023

This paper evaluates the evolving political will in Japan to restart nuclear power plants to generate electric power, in light of the country’s political and economic developments over the past few years. We apply a model of collective decision-making processes (CDMPs), using the KAPSARC Toolkit for Behavioral Analysis (KTAB), to simulate the interactions among different interest groups including policymakers, national and local political leaders, electricity companies, and the public, given their varying interests, goals and priorities.
Future of Fuels in the Aviation Sector
Authors:   King Abdullah Petroleum Studies and Research Center
Published: March 2023

Aviation is crucial for connecting people and countries worldwide. Although aviation carriers, manufacturers, and governments have all aimed to increase energy efficiency through significant technological advances over recent decades, this transport mode has struggled to find alternatives to fossil-based fuels. However, recent developments in low-carbon aviation fuel (LCAF), sustainable aviation fuel (SAF), hydrogen-based fuel, and electric power have improved the sustainability of the sector. As a result, a better understanding of the current use, future development, and new challenges of energy sources is essential for the future of the aviation industry.
Design application learning physics on material newton's law-based virtual lab
Authors: Theresia Wihelmina Mado  , Febriyanti Alwisye Wara  , Anastasia NM Saludale
Published: March 2023

Currently the world is experiencing an outbreak of the COVID 19 virus disease, so many people have become victims, so all activities are limited. This happens in the field of education, the learning atmosphere that usually takes place face-to-face has now changed to using online media from elementary to university level. PHYSICS learning in SMA is not only focused on concept theory but to support student centered learning, learning prioritizes the process of discovering and researching these materials and concepts themselves. Thus the existence of a laboratory becomes important where the purpose of holding learning in the laboratory is to develop student skills such as the use of tools, observation, train students carefully and recognize the limits of laboratory measurement abilities, train accuracy in recording, reporting, Results, stimulating critical thinking in experimental analysis, through the interpretation of experiments, deepen knowledge and develop responsibility and honesty as well as train students to plan and conduct experiments. But in reality, with the pandemic, students have difficulty in practical learning in the laboratory. Through the application of learning physics on Newton's law material based on the Virtual Lab, students can interactively interact with the application by choosing virtual practicum tools and materials. This application can be a tool for understanding learning so that it can increase student grades, especially during a pandemic.
How to better manage tourism in times of pandemic? Moving forward on a discussion we should have had before the 2020 crisis
Authors: Laura Sinay
Published: March 2023

Taking advantage of tourists’ intensive flow, the SARS-CoV-2 virus rapidly spread causing thousands of deaths globally. Trying to contain the already pandemic virus, government travel restrictions were suddenly imposed. Consequently, the tourism industry, which at that moment employed one in ten workers globally, suddenly collapsed. Hundreds of thousands of workers immediately lost their income. Flights were cancelled, and thousands of tourists were stuck abroad with no means to return to their home countries. The gravity of the situation raised the question of whether there was scholarly knowledge that could have helped manage tourism during the COVID-19 pandemic. To answer this question, a methodical literature review was performed, allowing for up to 900 publications to be analysed. The keywords used were pandemic, tourism, tourist and travel. Based on this process, 63 publications were selected for further analysis. Among these, less than 5% were focused on the tourism side of the problem. As such, this research concludes that, by the time the novel coronavirus emerged, there was, virtually, no scholarly knowledge on how to manage tourism during pandemic times so as to avoid chaos, and that the scholarly community studying related issues is very small. Moving forward, this article recommends that research funding agencies and universities encourage the sound development of this area of knowledge. Aspects that should be investigated include when, how and by whom should tourism be halted, as well as the feasibility of a Tourism World Fund for supporting related costs.
Biological activities of green synthesis silver nanoparticles by Plantago lanceolata L. leaves
Authors: Karakaş İ  , Sağır L. B  , Hacıoğlu Doğru N
Published: March 2023

In our study, silver nanoparticle (AgNP) was synthesized by green synthesis method using Plantago lanceolata L. leaves. The synthesized AgNPs were characterized using energy-dispersive spectra (EDS), scanning electron microscopy (SEM) and transmission electron microscope (TEM). The AgNPs were with an average size of 10–25 nm and mostly spherical. The antimicrobial potential of AgNPs was tested against some bacteria and a yeast culture by disc diffusion and minimum inhibitory concentration (MIC) methods. The AgNPs were significantly inhibited all test culture except Bacillus subtilis ATCC 6633. Antioxidant activities were determined by 2,2-diphenyl-1-picrylhydrazil (DPPH) free radical scavenging and 2,2'- Azino-bis (3-ethylbenzothiazolin-6-sulfonic acid) (ABTS•+) cation radical scavenging activity. The higher DPPH and ABTS of AgNPs were determined 33.20±0.50% and 39.37±0.54%, respectively. Thus, green synthesis AgNPs may be a new alternative therapeutic agent for infection therapy.
Microspheres and their applications in drug delivery system
Authors: Kasturi Monika  , K. Anie Vijetha
Published: March 2023

This article focuses on microspheres, types, preparation and their applications in drug delivery system. based on recent literatures. The microspheres are used for drug delivery that offers a potent therapeutic substitute for traditional or immediate-release single-unit dose forms. Microspheres are solid objects with diameters ranging from 1 to 1000µ m. The numerous types of microsphere are employed in the delivery of medications. The efficacy and administration strategies of the variously produced microspheres differ from those of standard dose forms. The microsphere is evaluated using a variety of methods that analyse the microsphere's quality. Finally brief summary of the current difficulties in processing these microspheres, which calls for additional study and development, is offered in the end.
Design, analysis and fabrication of hydro fixture for testing of 32” and above size valve
Authors: Sudhansu Sekhar Das  , M Sudhahar
Published: March 2023

A hydrostatic test is a way in which pressure vessels such as pipelines, plumbing, gas cylinders, boilers and fuel tanks can be tested for strength and leaks. The test involves filling the vessel or pipe system with a liquid, usually water, which may be dyed to aid in visual leak detection, and pressurization of the vessel to the specified test pressure. Pressure tightness can be tested by shutting off the supply valve and observing whether there is a pressure loss. The location of a leak can be visually identified more easily if the water contains a colorant. Strength is usually tested by measuring permanent deformation of the container. Hydrostatic testing is the most common method employed for testing pipes and pressure vessels. Using this test helps maintain safety standards and durability of a vessel over time. Newly manufactured pieces are initially qualified using the hydrostatic test. They are then re-qualified at regular intervals using the proof pressure test which is also called the modified hydrostatic test .Testing of pressure vessels for transport and storage of gases is very important because such containers can explode if they fail under pressure. Hydrostatic tests are conducted under the constraints of either the industry's or the customer's specifications, or may be required by law. The vessel is filled with a nearly incompressible liquid - usually water or oil - pressurized to test pressure, and examined for leaks or permanent changes in shape. The test pressure is always considerably higher than the operating pressure to give a factor of safety.
Assessment of consumption patterns of soft drinks and its impact on nutritional status among young adults of Kolkata
Authors: Sridatry Pal  , Joyeta Ghosh  , Sudrita Roy Choudhury  , Khusboo Singh  , Samarpita Koner
Published: March 2023

Soft drinks are non-alcoholic beverages that primarily consist of fruit juices and carbonated beverages. Soft drinks and other liquids with added sugar are viewed as unhealthy food items since they are high in calories but low in nutrients. India's populace continues to crave sugary soft drinks even as the rest of the globe is losing interest in these toxic beverages. The purpose of the present study was to determine the association between consumption of soft drinks and its impacts on nutritional status. This cross-sectional study was conducted among 100 younger adults, aged 20-30 years selected randomly from different social media resources based on Kolkata, West Bengal India. Present online survey was conducted on the basis of responses obtained from using pretested standardised questionnaires. The google forms were prepared and shared with the respondents. Social media platforms were used like Facebook, WhatsApp, LinkedIn. In the present study total 2% respondents were underweight,30% were normal and 68% respondents belonged to overweight/obesity.88% of respondents are aware about the unhealthy impact of soft drinks. Whereas considering practice 6% of the respondents drink soft drinks daily and 25% have it on a weekly basis.42% of the respondents prefers regular soft drinks whereas 46% prefers fruit flavoured cold drinks. Again 62% of the respondents prefers coloured soft drinks. Considering attitude of the respondents 12% of them still willing to have soft drinks even after knowing its ill effects on tooth enamel. Further studies using descriptive research designs are needed to better understand the prospective associations among beverage consumption and obesity in the age group of 20 to 30 years, who are the future of our country.
Journey of genetically modified crops: Status and prospects
Authors: Gyana Ranjan Rout  , Rinny Swain  , Debee Prasad Sahoo
Published: March 2023

Background and Objective: Agricultural biotechnology has major concern with genetic improvement of crops to increase their yields or efficiency, genetic characterization & conservation of plant genetic resources and disease diagnosis. Advance biotechnological techniques help in crop improvement as well as crop productivity. The introgression of different traits into crops was preceded through selection and by rapid development in plant breeding in the 20th century. Transgenic technology helps to develop genetically modified crops which are resistant to abiotic and biotic stresses. Apart from this, the different transgenic crops are commercially released, but some of them are not yet released with traits with special reference to bio-fortification, phytoremediation and production of nutritional value i.e., rice with significant level of zinc and iron nutrients and bananas with vitamins. Conclusion: The review highlights the present status and future prospects of genetic modified crops and model framework for commercialization need for sustainable agriculture. Apart from that recent technological advancement in the field of genome editing using engineered nucleases has provided new opportunities for development and commercialization of genetic modified plants.
Validation of an ELISA test kit for the quantitative analyses of total Aflatoxins in spices marketed in Cameroon
Authors: Evelyne Nguegwouo  , Azoumboi Abassi Nouhou  , Abel Wade  , Gabriel Nama Medoua  , Elie Fokou
Published: March 2023

Aﬂatoxins (mold-synthetized secondary metabolites) contamination associated with food such as spices continue to be a global problem in the world. The aim of this study was to measure the standard parameters of validation (Linearity, occuracy, repeatability, intermediate precision, reproducibility, limit of detection, limit of quantification and robustness) of the total Aflatoxins (AFt) low-matrix Enzyme-Linked ImmunoSorbent Assay (ELISA) Kit (Lot No. 062218, RENEKABIO, USA) and used this method to evaluate the contamination degree of AFt ( AFB1, AFB2, AFG1 and AFG2) in 4 different spice matrices [white pepper (Piper nigrum), black pepper (Piper nigrum), njansang (Ricinodendron heudelottii) and super épice mbongo ( Mix of Aframomum citratum, Monodora myristica and Afrostyrax lepidophyllus] marketed in Cameroon and commonly used as ingredients in Cameroonian sauces. The test was performed as a solid phase direct competitive ELISA using a horse radish peroxidase conjugate as the competing, measurable entity. Data obtained from validation showed linearity in the range between 0 mg kg-1 and 20 mg kg-1; an accuracy marked by a recovery rate ranging from 95.09 % to 110.29 %; a coefficient of variation (CV) of repeatability of 3.14 %, a coefficient of variation (CV) of intermediate precision of 6.82 % and a coefficient of variation (CV) of reproducibility of 13.96 %. Detection and quantification limits of 0.15 mg kg -1 and 0.50 mg kg -1 were determined, respectively. The robustness test revealed a critical point of the method as an incubation for 30 minutes at room temperature. The application of the method to our spices analyzed revealed 100 % contamination of 2.34 ± 0.25 µg kg -1 (white pepper), 2.37 ± 0.38 µg kg -1 (black pepper), 2.58 ± 0.87 µg kg -1 (Njansang) and 6.60 ± 5.21 µg kg -1 (Super épice mbongo). The RENEKABIO low matrix ELISA kit used for this research enables an accurate, reliable and faithful screening and quantification of AFt in spice matrices. This will be an asset in quality control of spices marketed in Cameroon.
Perubahan karakteristik cetakan green sand dan cacat inklusi pasir akibat perubahan kadar bentonit
Authors: Sutiyoko Sutiyoko , Madani Fatwa
Published: March 2023

Bentonit merupakan salah satu bahan utama dalam cetakan green sand dan berpengaruh pada karakteristik cetakan serta hasil benda cor. Kadar bentonit mempengaruhi permeabilitas, kompaktibilitas, kekuatan geser, dan kekuatan tekan cetakan green sand. Tujuan penelitian ini adalah untuk mengetahui perubahan karakteristik cetakan greensand akibat perubahan kadar bentonit serta pengaruhnya terhadap cacat inklusi pasir. Variasi kadar bentonit sebesar 3,5 % dan 4,3 % dari berat total bahan cetakan. Pengujian cetakan mencakup uji mampu bentuk, kekuatan tekan, dan kadar air. Uji coba pada benda cor disc brake mobil untuk menganalisa pengaruhnya terhadap cacat cor yang terjadi. Hasil pengujian karakteristik cetakan green sand menunjukkan bahwa kadar bentonit 3,5 % memiliki mampu tekan cetakan 13,7±0,4 N/cm2 (standar : 14 – 18 N/cm2) dan mampu bentuk cetakan 34±5,1 % (standar: 33 – 58 %). Kedua karakteristik ini masih berada di bawah standar cetakan green sand. Kadar bentonit 4,3 % memiliki karakteristik cetakan yang sesuai dengan standar cetakan green sand untuk semua karakteristik cetakan yang diuji. Hasil pengecoran besi cor nodular menunjukkan terjadinya cacat inklusi pasir pada benda cor. Kekurangan kadar bentonit menurunkan mampu bentuk cetakan sehingga cetakan mudah rontok ketika cairan logam masuk. Rontoknya cetakan ini dapat membawa pasir sehingga terjadi inklusi pasir pada benda cor. Demikian halnya dengan mampu tekan cetakan yang di bawah standar. Kekuatan tekan rendah memungkinkan cetakan erosi ketika terkena tekanan cairan logam.
Impact of Data Balancing and Feature Selection on Machine Learning-based Network Intrusion Detection
Authors: Barkah Azhari Shouni , Selamat Siti Rahayu , Abidin Zaheera Zainal , Wahyudi Rizki
Published: March 2023

Unbalanced datasets are a common problem in supervised machine learning. It leads to a deeper understanding of the majority of classes in machine learning. Therefore, the machine learning model is more effective at recognizing the majority classes than the minority classes. Naturally, imbalanced data, such as disease data and data networking, has emerged in real life. DDOS is one of the network intrusions found to happen more often than R2L. There is an imbalance in the composition of network attacks in Intrusion Detection System (IDS) public datasets such as NSL-KDD and UNSW-NB15. Besides, researchers propose many techniques to transform it into balanced data by duplicating the minority class and producing synthetic data. Synthetic Minority Oversampling Technique (SMOTE) and Adaptive Synthetic (ADASYN) algorithms duplicate the data and construct synthetic data for the minority classes. Meanwhile, machine learning algorithms can capture the labeled data's pattern by considering the input features. Unfortunately, not all the input features have an equal impact on the output (predicted class or value). Some features are interrelated and misleading. Therefore, the important features should be selected to produce a good model. In this research, we implement the recursive feature elimination (RFE) technique to select important features from the available dataset. According to the experiment, SMOTE provides a better synthetic dataset than ADASYN for the UNSW-B15 dataset with a high level of imbalance. RFE feature selection slightly reduces the model's accuracy but improves the training speed. Then, the Decision Tree classifier consistently achieves a better recognition rate than Random Forest and KNN.
Mapping User Experience Information Overload Problems Across Disciplines
Authors: Kusuma Wahyu Andhyka , Jantan Azrul Hazri , Abdullah Rusli Bin , Admodisastro Novia , Mohd Norowi Noris Binti
Published: March 2023

User Experience (UX) has been increasing linearly with the systems and digital media. UX concept describes a human factor as an experience with the life cycle of digital technology. UX increases the usability of the product in the industry more than functionality. Interest in UX has produced a huge amount of product and research articles. Moreover, this interdisciplinary topic becomes increased significantly because of the wider applications. However, this benefit become a problem due to the number of publications. The information overload problem is the result of the increasing UX topic. Several researchers solved this problem with qualitative analysis, but it cannot solve the overload problem. In this paper, we purposed bibliometric analysis and research profiling to interpret UX information on the map, with the publications from 1998-2022, a dataset compiled in RIS format to provide article metadata. As a result, the UX information map from the topic with the five clusters. Therefore, to provide information on the topic's coherence, we propose a coupling network. A related topic is shown as a link; a direct link means high coherence between topics. The analysis was carried out using the 5W1H approach (what, where, who, when, why, and how). The results show that UX is indeed an interdisciplinary field, especially with a design approach and user experience. In addition, to determine novice researchers, determining the focus of research can be done by taking into account previous research goals and maps.
Solar Powered Vibration Propagation Analysis System using nRF24l01 based WSN and FRBR
Authors: Wedashwara Wirarama , Yadnya Made Sutha , Sudiarta I Wayan , Arimbawa I Wayan Agus , Mulyana Tatang
Published: March 2023

Prevention of the effects caused by natural disasters such as earthquakes and landslides requires analysis of vibration propagation. In outdoor applications, internet sources such as WIFI are not always available, so it requires alternative data communications such as nRF24l01. The system also requires a portable power source such as solar power. This research aims to develop a vibration propagation analysis system based on the nRF24l01 wireless sensor network and solar power by implementing the fuzzy rule-based regression (FRBR) algorithm. The system consists of two piezoelectric and nrf24l01 vibration sensors. The system also uses a third node equipped with temperature and soil moisture sensors, air temperature and humidity, and light intensity as environmental variables. The evaluation results show the Quality of Services (QoS) results with a throughput of 99.564%, PDR 99.675%, and a delay of 0.0073s. The Fuzzy Association Rule (FAR) extraction results yield nine rules with average support of 0.319 and confidence of 1 for vibration propagation. The availability of solar power was evaluated with an average current value of 0.250A and a voltage of 3.266V. The results of FRBR are based on the propagation of the vibration that propagated and produced a mean square error (MSE) of 0.141 and a mean absolute error (MAE) of 0.165. The correlation matrix and FAR results show that only soil moisture has a major effect on the magnitude and duration of propagation. However, other variables can regress soil moisture with MSE 0.232 and MAE 0.287.
Small Scale Aerial Monitoring for Human Body Temperature Measurement Using Rotary Wing Drone
Authors: Sani Muhammad Ikhsan , Siregar Simon , Hamdani Farhan , Nanda Bagas Musamma , Febriansyah Ryan
Published: March 2023

In Indonesia, the COVID-19 pandemic has had an impact on a variety of sectors. Using all available technology for disaster mitigation is critical for pandemic prevention and control. Recent studies have uncovered the advantage of Unmanned Aerial Vehicle (UAV) or drones, particularly those with rotary wings, in dealing with the pandemic. Much effort has been devoted to developing a rotary-wing drone system as a flying platform for aerial monitoring. However, several factors must be considered when visually observing a specific region, i.e., the area's size, topographic contours, locations of special interest inside the area, approach points to the area, and the observation timeframe. Since fever is a common symptom of COVID-19, human body temperature monitoring is highlighted for fever screening, with the objective of minimizing people with high body temperatures going to the crowd. A major challenge is creating a system that can provide accurate body temperature data, which is critical for fighting the pandemic. The purpose of this paper is to present a rotary wing drone application for aerial human body temperature measurements. The paper also proposed an alternative solution based on using a portable, low-cost, Forward-looking Infrared (FLIR) thermal imaging camera. The FLIR thermal camera is incorporated into the drone's electronic system. Furthermore, thermal image data are transmitted into the ground station via a radio telemetry transceiver to allow flexible surveillance by the operator. Indoor and outdoor experiments reveal that the system has been effectively installed and provide data collection for further research. The results show that the system can be used for small-scale area aerial monitoring.
Evaluation of the Visual Learning Application for Mathematics using Holography Display for the topic on Shape and Space
Authors: Khoo Shiang Tyng , Badioze Zaman Halimah , Mohamad Ummul Hanan , Ahmad Azlina
Published: March 2023

Mathematics is an important foundation in the life of an individual. The problems associated with learning Mathematics that are commonly encountered, are due to factors such as: abstract phenomena and concepts, low imagination, and lack of understanding of the concepts being studied. Thus, the purpose of this study is to help primary school children improve their ability to recognise 3D shapes that are abstract phenomena. This paper presents the Effectiveness Usability Evaluation of the Visual Learning Application for Mathematics using Holography Display for the topic on Shape and Space called MEL-VIS. This study was conducted on eighty (80) primary school students. The results of the study showed that learning about 3D shapes with the E-Visual MEL-VIS application prototype is more effective than traditional methods.