bluuebunny/crossref_metadata_2025 huggingface dataset:
Opioid Sparing at 24 h after Total Shoulder Arthroplasty by Undiluted Liposomal Bupivacaine Single Shot Interscalene Block: A Randomized Clinical Trial, First Results
Authors: Jindia Lauren , Christensen Justin , Deng Jin , Puri Suvikram , Balouch Maha , Haidamous George , Frankle Mark , Camporesi Enrico Mario
Published: February 2022

Background: The purpose of this study was to compare postoperative opioid consumption following total shoulder arthroplasty, after: (A) a single-shot undiluted liposomal bupivacaine (LB; commercial name: Exparel) interscalene block, or (B) a Ropivacaine block (R), supplemented with continuous catheter infusion. Methods: This prospective, randomized study (NCT03739021) compared postoperative analgesic requirements in Morphine Milligram Equivalent (MME) during the first 24 h after discharge from the post-anesthesia care unit (PACU) in patients receiving total shoulder arthroplasty. Two similar groups of 30 patients each received equivalent general operative anesthesia. Preoperative interscalene block was performed with either 10mL of undiluted liposomal bupivacaine (LB) or ropivacaine (R) 0.5% plus continuous catheter infusion. Results: There were no differences between the two groups regarding age, gender, length of surgery, intraoperative narcotic usage, or length of hospital stay. The time required to administer (LB) compared to (R) was significantly reduced (5 min vs. 15 min). The LB group experienced a reduction in MME during the first 24 h after PACU discharge (25 vs. 41 MME). Conclusion: A single shot of undiluted liposomal bupivacaine (LB) provided a significant (p = 0.045) reduction in opioid use during the first 24 h after shoulder replacement surgery compared to ropivacaine (R) with continuous catheter infusion. A larger sample group will be required to bolster these results. There was no measured difference in reported pain level. LB also took less time to administer.
Thermodynamic Modeling of the Uranium–Tellurium System: Estimation of the Uncertainties by a Bayesian Approach
Authors: Guéneau Christine , Lawrence Eva , Klein Thierry , Gamboa Fabrice
Published: February 2022

Under irradiation, the formation of fission products in the (U,Pu)O2 fuel with time has a substantial effect on its chemistry. In particular, migration of the most volatile fission products (Cs, Te, I, Mo) from the center to the periphery of the fuel pellet is induced by the large radial thermal gradient. To predict the thermodynamic properties of the irradiated fuel, thermodynamic modeling of the complex multi-component (Cs-I-Te-Mo)–(U-Pu)–O system is performed using the CALPHAD method. In this work, the thermodynamic assessment of the U–Te sub-system is performed. The literature review reveals a lack of experimental data as well as scattering and inconsistency of some of the data. In particular, no thermodynamic data exist on the liquid. From this review, input thermodynamic and phase diagram data are carefully selected. The Gibbs energy functions are then adjusted by fitting these data. An overall good agreement is obtained with all the selected data except for the enthalpy of formation for UTe which is underestimated by 13% by our model. This could be due to an inconsistency between the enthalpy of formation and vapor pressure data. In a second step, the uncertainties on the thermodynamic parameters and their propagation on the calculated thermodynamic and phase diagram data are estimated using a Bayesian approach. The analysis shows that there are too many parameters (22) for too few data points (120 points). The uncertainties are thus large on some of the calculated data. Moreover the inconsistency of some of the data and the lack of thermodynamic data for the liquid makes the model uncertain. New experimental data such as heat capacity, enthalpy of formation for the compounds, and chemical potentials or activities for the liquid phase would improve the reliability of our model. Measurements of phase diagram data in the U–UTe2 region are also required. However this work provides the first detailed uncertainty analysis of the U–Te CALPHAD model. Moreover our approach, contrary to other Bayesian methods, provides an analytical posterior probability distribution and analytical credible intervals for the calculated thermodynamic quantities. It also speeds up the simulation of the uncertainty estimations on the phase diagram.
Management Accounting Practices in the Hospitality Industry: A Systematic Review and Critical Approach
Authors: Campos Filipa , Lima Santos Luís , Gomes Conceição , Cardoso Lucília
Published: February 2022

The hospitality industry has been making a remarkable contribution to the growth of several countries’ economies. From a business perspective, the best management accounting (MA) techniques and practices are fundamental to the success of companies. However, studies in this specific area in the hotel industry are scattered in the scientific literature in different types of documents and different languages, and with an irregular distribution throughout the years (2000–2020). To fill this gap, a thorough analysis of the global performance of management accounting practices in hospitality is crucial. This study accessed the Web of Science database in three different languages and systematized the articles to be included in this research through the PRISMA guidelines, which allowed an empirical basis for the critical approach to this topic. The greatest relevance of the study is the fact that it presents a systematic review of the literature on hotel management accounting practices, for which these results were enriched with a critical approach. The innovative character of the study focuses on evidence of the increasing implementation of some hotel management accounting practices over the years, such as some operating ratios and the USALI. In practical terms, the results of this study explain the overall performance of management accounting practices in the lodging industry and which ones are most widely used. The importance of the practices to support the decision-making of hoteliers and the challenges that they need to face in their implementation are also shown.
Effect of Combined Soil Amendment on Immobilization of Bioavailable As and Pb in Paddy Soil
Authors: Hong Young-Kyu , Kim Jin-Wook , Lee Sang-Phil , Yang Jae-E. , Kim Sung-Chul
Published: February 2022

Heavy metal pollution in soil can have detrimental effects on soil ecosystems and human health. In situ remediation techniques are widely used to reduce the bioavailable fractions of heavy metals in soil. The main objective of this study was to examine the reduction of the bioavailable fractions of As and Pb in paddy soil with artificial lightweight material (ALM) manufactured from recycled materials. A total of four treatments, including a control (no amendment), ALM10 (10% of ALM in soil), ALM10+L (10% ALM combined with 0.5% lime), and ALM10+FeO (10% ALM combined with 0.5% FeO), were applied to paddy fields, and rice (Oryza sativa L.) was cultivated after 32 weeks. The highest reduction efficiencies for the bioavailable fractions of As and Pb in soil were observed in the ALM10+FeO (52.8%) and ALM10+L treatments (65.7%), respectively. The uptake of As decreased by 52.1% when ALM10+FeO was applied to paddy soil, and that of Pb decreased by 79.7% when ALM10+L was applied. Correlation analysis between bioavailable heavy metals in soil and soil chemical properties showed that soil pH, electrical conductivity (EC), P2O5, and soil organic matter (SOM) were the main factors controlling the mobility and bioavailability of As and Pb. Overall, the efficiencies of As and Pb reduction increased synergistically in both soil and plants when FeO and lime were combined with the ALM. In future studies, long-term monitoring is necessary to examine the longevity of soil amendments.
Potential Role of Individual and Combined Effects of T-2 Toxin, HT-2 Toxin and Neosolaniol on the Apoptosis of Porcine Leydig Cells
Authors: Xu Jingru , Zhao Zhihui , Guo Wenbo , Ling Aru , Wang Jianhua , Wang Xichun , Yang Junhua
Published: February 2022

T-2 toxin usually co-occurs with HT-2 toxin and neosolaniol (NEO) in the grains and feed. Our previous studies found that T-2 toxin and its metabolites’ binary or ternary combination exposure to porcine Leydig cells (LCs) displayed synergism in certain range of dosage and cannot be predicted based on individual toxicity. However, the possible mechanism of these mycotoxins’ combined exposure to cell lesions remains unknown. Based on 50% cell viability, the mechanism of apoptosis in porcine Leydig cells was investigated after exposure to T-2, HT-2, NEO individual and binary or ternary combinations. Compared with control, the adenosine triphosphate (ATP) content decreased, reactive oxygen species (ROS) level increased, and mitochondrial membrane potential (MMP) decreased in all treated groups. Additionally, the cell apoptosis rates were significantly increased in test groups (p < 0.05), and the B-cell lymphoma 2 (Bcl-2) Associated X (Bax)/Bcl-2 ratio and the expression of caspase 3, caspase 8, cytochrome c (Cytc) in the treated group are all significantly higher than the control group. Moreover, the expression of Cytc and caspase 8 gene in NEO and T-2+NEO groups was significantly higher than that in other individual and combined groups. It can be concluded that the toxicities of T-2, HT-2, and NEO individually and in combination can induce apoptosis related to the oxidative stress and mitochondrial damage, and the synergistic effect between toxins may be greater than a single toxin effect, which is beneficial for assessing the possible risk of the co-occurrences in foodstuffs to human and animal health.
Renormalizing Open Quantum Field Theories
Authors: Nagy Sandor , Polonyi Janos
Published: February 2022

The functional renormalization group flow of a scalar field theory with quartic couplings and a sharp spatial momentum cutoff is presented in four-dimensional Minkowski space-time for the bare action by retaining the entanglement of the IR and the UV particle modes. It is argued that the open interaction channels have to be taken into account in quantum field theory defined by the help of a cutoff, and a non-perturbative UV-IR entanglement is found in closed or almost closed models.
Trojan Horse Investigation for AGB Stellar Nucleosynthesis
Authors: Sergi Maria Letizia , D’Agata Giuseppe , Guardo Giovanni Luca , Rapisarda Giuseppe Gabriele , Burjan Vaclav , Cherubini Silvio , Gulino Marisa , Indelicato Iolanda , La Cognata Marco , Lamia Livio , Lattuada Dario , Mrázek Jaromir , Oliva Alessandro Alberto , Pizzone Rosario Gianluca , Romano Stefano , Spartá Roberta , Trippella Oscar , Tumino Aurora
Published: February 2022

Asymptotic Giant Branch (AGB) stars are among the most important astrophysical sites influencing the nucleosynthesis and the chemical abundances in the Universe. From a pure nuclear point of view, several processes take part during this peculiar stage of stellar evolution thus requiring detailed experimental cross section measurements. Here, we report on the most recent results achieved via the application of the Trojan Horse Method (THM) and Asymptotic Normalization Coefficient (ANC) indirect techniques, discussing the details of the experimental procedure and the deduced reaction rates. In addition, we report also on the on going studies of interest for AGB nucleosynthesis.
COVID-19 Vaccination Improved Psychological Distress (Anxiety and Depression Scores) in Chronic Kidney Disease Patients: A Prospective Study
Authors: Garcia-Llana Helena , Panizo Nayara , Gandía Lorena , Orti Marisa , Giménez-Civera Elena , Forquet Claudia , D’Marco Luis , Puchades Maria Jesús , Sargsyan Mari , Sanchís Irina , Ribera Carmen , Marco Mª Inés , Ferrá Cristela Moncho , Pérez-Baylach Carmen María , Bonilla Begoña , Moncho Francés Francesc , Perez-Bernat Elisa , Sancho Asunción , Górriz Jose Luis
Published: February 2022

The purpose of the study is to analyze the impact of vaccination against SARS-CoV-2 on anxiety and depression scores in patients with different modalities of chronic kidney disease. One hundred and seventeen renal patients (50 hemodialysis patients, 13 peritoneal dialysis patients, 32 kidney transplants, and 22 advanced chronic kidney disease patients at pre-dialysis care) were evaluated for depression, anxiety, health-related quality of life (HRQOL), and perceived fears and resources with standardized (Hospital Anxiety and Depression Scale (HADS)) and self-reported questionnaires. The measure points were before vaccination and 15 days after vaccination. The main finding of the study was that there was a decrease in the global mean of normal scores for anxiety and depression symptoms in chronic kidney disease patients post-vaccination. We did not find statistically significant differences in depression or anxiety scores, nor any HRQOL differences between the treatment groups. The three main fears reported by the participants at baseline were those of adverse effects, not getting the vaccine, and lack of information. These findings highlight the potential interest of assessing psychological variables related to the impact of vaccination against SARS-CoV-2. New studies will be required to assess the impact of comprehensive vaccine coverage and its psychological impact.
Capturing a Crucial ‘Disorder-to-Order Transition’ at the Heart of the Coronavirus Molecular Pathology—Triggered by Highly Persistent, Interchangeable Salt-Bridges
Authors: Roy Sourav , Ghosh Prithwi , Bandyopadhyay Abhirup , Basu Sankar
Published: February 2022

The COVID-19 origin debate has greatly been influenced by genome comparison studies of late, revealing the emergence of the Furin-like cleavage site at the S1/S2 junction of the SARS-CoV-2 Spike (FLCSSpike) containing its 681PRRAR685 motif, absent in other related respiratory viruses. Being the rate-limiting (i.e., the slowest) step, the host Furin cleavage is instrumental in the abrupt increase in transmissibility in COVID-19, compared to earlier onsets of respiratory viral diseases. In such a context, the current paper entraps a ‘disorder-to-order transition’ of the FLCSSpike (concomitant to an entropy arrest) upon binding to Furin. The interaction clearly seems to be optimized for a more efficient proteolytic cleavage in SARS-CoV-2. The study further shows the formation of dynamically interchangeable and persistent networks of salt-bridges at the Spike–Furin interface in SARS-CoV-2 involving the three arginines (R682, R683, R685) of the FLCSSpike with several anionic residues (E230, E236, D259, D264, D306) coming from Furin, strategically distributed around its catalytic triad. Multiplicity and structural degeneracy of plausible salt-bridge network archetypes seem to be the other key characteristic features of the Spike–Furin binding in SARS-CoV-2, allowing the system to breathe—a trademark of protein disorder transitions. Interestingly, with respect to the homologous interaction in SARS-CoV (2002/2003) taken as a baseline, the Spike–Furin binding events, generally, in the coronavirus lineage, seems to have preference for ionic bond formation, even with a lesser number of cationic residues at their potentially polybasic FLCSSpike patches. The interaction energies are suggestive of characteristic metastabilities attributed to Spike–Furin interactions, generally to the coronavirus lineage, which appears to be favorable for proteolytic cleavages targeted at flexible protein loops. The current findings not only offer novel mechanistic insights into the coronavirus molecular pathology and evolution, but also add substantially to the existing theories of proteolytic cleavages.
The Effect of Smoking on Humoral Response to COVID-19 Vaccines: A Systematic Review of Epidemiological Studies
Authors: Ferrara Pietro , Gianfredi Vincenza , Tomaselli Venera , Polosa Riccardo
Published: February 2022

While the role of active smoking on response to vaccines is yet to be fully understood, some real-world studies have outlined a possible link between smoking and humoral response to COVID-19 vaccines. Thus, the present rapid systematic review aimed at summarizing the current epidemiological evidence on this association. Following PRISMA and WHO guidelines on rapid systematic reviews, we systematically reviewed published literature on this topic and discussed the findings according to the aim of analysing smoking and its impact on humoral response to COVID-19 postvaccination antibody titres. The search strategy yielded a total of 23 articles. The sample size amongst the studies ranged between 74 and 3475 participants (median, 360), with the proportion of smokers being between 4.2% and 40.8% (median, 26.0%). The studies included in this review analysis investigated the dynamics of antibody response to different type of COVID-19 vaccines. In 17 out of 23 studies, current smokers showed much lower antibody titres or more rapid lowering of the vaccine-induced IgG compared with nonsmokers. This rapid systematic review indicates that active smoking negatively impacts humoral response to COVID-19 vaccines, although the pathophysiologic mechanisms for this association have not been entirely suggested. The results advocate targeted policies to promote tailored health promotion initiatives, which can increase risk perception and ensure appropriate protection measures to be taken to avoid the health consequences of COVID-19 in smokers.
A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV
Authors: Pavulraj Selvaraj , Pannhorst Katrin , Stout Rhett W. , Paulsen Daniel B. , Carossino Mariano , Meyer Denise , Becher Paul , Chowdhury Shafiqul I.
Published: February 2022

Porcine circovirus type 2 (PCV2) is endemic worldwide. PCV2 causes immunosuppressive infection. Co-infection of pigs with other swine viruses, such as pseudorabies virus (PRV) and classical swine fever virus (CSFV), have fatal outcomes, causing the swine industry significant economic losses in many if not all pig-producing countries. Currently available inactivated/modified-live/vectored vaccines against PCV2/CSFV/PRV have safety and efficacy limitations. To address these shortcomings, we have constructed a triple gene (thymidine kinase, glycoprotein E [gE], and gG)-deleted (PRVtmv) vaccine vector expressing chimeric PCV2b-capsid, CSFV-E2, and chimeric Erns-fused with bovine granulocytic monocyte-colony stimulating factor (Erns-GM-CSF), designated as PRVtmv+, a trivalent vaccine. Here we compared this vaccine’s immunogenicity and protective efficacy in pigs against wild-type PCV2b challenge with that of the inactivated Zoetis Fostera Gold PCV commercial vaccine. The live PRVtmv+ prototype trivalent subunit vaccine is safe and highly attenuated in pigs. Based on PCV2b-specific neutralizing antibody titers, viremia, viral load in lymphoid tissues, fecal-virus shedding, and leukocyte/lymphocyte count, the PRVtmv+ yielded better protection for vaccinated pigs than the commercial vaccine after the PCV2b challenge. Additionally, the PRVtmv+ vaccinated pigs generated low to moderate levels of CSFV-specific neutralizing antibodies.
Prevalence of COVID-19 Infection among Patients with Diabetes and Their Vaccination Coverage Status in Saudi Arabia: A Cross-Sectional Analysis from a Hospital-Based Diabetes Registry
Authors: Tourkmani Ayla , Bin Rsheed Abdulaziz , AlEissa Mohammad , Alqahtani Sulaiman , AlOtaibi Azzam , Almujil Mohammed , AlKhshan Ibraheem , ALNassar Turki , ALOtaibi Mansour , Alrasheedy Alian
Published: February 2022

Patients with diabetes have a higher risk of severe infection and mortality due to COVID-19. Considering the current limited effective pharmacological treatments, vaccination remains one of the most effective means to control the pandemic. The current study aimed to determine the prevalence of COVID-19 infection and the rate of COVID-19 vaccination coverage among patients with type 2 diabetes mellitus. The patients were identified from a diabetes hospital registry at Prince Sultan Military Medical City, Riyadh, Saudi Arabia in July 2021. The history of COVID-19 infection and the vaccination status were retrieved from the National Health Electronic Surveillance Network (HESN) program and the Seha platform, respectively. A total of 11,573 patients were included in this study (representing 99.5% of all patients in the registry). A total of 1981 patients (17.1%) had a history of confirmed COVID-19 infection. The rate of vaccination with a 1st dose was 84.8% (n = 9811), while the rate of full vaccination with the 2nd dose was 55.5% (n = 6422). The analysis showed that a higher proportion of male patients were fully vaccinated than female patients (61.0% versus 51.2%, p < 0.001). There were statistically significant differences among the age groups, with the full vaccination rate ranging from 59.0% for the 61–70-year-old age group to 49.0% for the > 80-year-old age group (p < 0.001). The patients with no previous history of COVID-19 infection were more likely to get fully vaccinated than those with a previous history of the infection (63.9% versus 14.6%, respectively, p < 0.001). The factors associated with a higher likelihood of unvaccinated status included the female gender (adjusted odds ratio (aOR) = 1.705 (95% confidence interval (CI): 1.528–1.902)), elderly patients in the age group of 61–70 (aOR (95% CI) = 1.390 (1.102–1.753)), the age group of 71–80 (aOR (95% CI) = 1.924 (1.499–2.470)) and the age group of >80 (aOR (95% CI) = 3.081 (2.252–4.214), and prior history of COVID-19 infection (aOR (95% CI) = 2.501 (2.223–2.813)). In conclusion, a considerable proportion of patients with type 2 diabetes had confirmed COVID-19 infection. Continued targeted efforts are needed to accelerate vaccination coverage rates among patients with diabetes in general and the particular subgroups identified in this study.
Observation Experiment of Wind-Driven Rain Harvesting from a Building Wall
Authors: Yoo Chulsang , Cho Eunsaem , Lee Munseok , Kim Soeun
Published: February 2022

Rainwater harvesting is generally assumed to collect rainwater from the roof or ground. However, this study shows that this structural limitation of rainwater harvesting can be overcome by employing a building wall. The rainfall on a building wall is called wind-driven rain (WDR), which is the target for the rainwater harvesting addressed in this study. To prove the possibility of WDR harvesting, this study prepared three different gauges to collect the rainwater from a building wall. These gauges are like miniature buildings used to collect the WDR on the building wall inside a storage tank at the bottom. The WDR harvesting gauges were located on the rooftop of the Engineering Building, Korea University, and a total of 15 rainfall events were observed during the rainy season in Korea from June to September 2020. Our analysis of the collected data confirms the significant role of the building wall in rainwater harvesting. For a building height of 0.5 m, the rainwater additionally harvested from the wall was about 40% that from the roof, which became about 70% for the height of 1.0 m and about 90% for the height of 1.5 m. In addition, Cho et al. (2020)’s empirical equation for estimating the WDR is found to be useful for estimating the amount of rainwater harvested from the building wall. The correlation coefficients between the measurements and estimates were estimated to be high as 0.94, 0.92 and 0.91 for building heights of 0.5 m, 1.0 m, and 1.5 m, respectively.
Bivariate Nonstationary Extreme Flood Risk Estimation Using Mixture Distribution and Copula Function for the Longmen Reservoir, North China
Authors: Li Quan , Zeng Hang , Liu Pei , Li Zhengzui , Yu Weihou , Zhou Hui
Published: February 2022

Recently, the homogenous flood generating mechanism assumption has become questionable due to changes in the underlying surface. In addition, flood is a multifaced natural phenomenon and should be characterized by both peak discharge and flood volume, especially for flood protection structures. Hence, in this study, data relating to the 55-year reservoir inflow, annual maximum flood peak (AMFP), and annual maximum flood volume (AMFV) for the Longmen Reservoir in North China have been utilized. The 1-day AMFV exhibits a significant correlation with AMFP. The extreme flood peak-volume pairs are then used to detect the heterogeneity and to perform nonstationary flood risk assessment using mixture distribution as the univariate marginal distribution. Moreover, a copula-based bivariate nonstationary flood frequency analysis is developed to investigate environmental effects on the dependence of flood peak and volume. The results indicate that the univariate nonstationary return period is between the joint OR and the AND return periods. The conditional probabilities of 1-day AMFV, when AMFP exceeds a certain threshold, are likely to be high, and the design flood values estimated by joint distribution are larger than the ones in the univariate nonstationary context. This study can provide useful information for engineers and decision-makers to improve reservoir flood control operations.
Determination of Physicochemical Water Quality of the Ghis-Nekor Aquifer (Al Hoceima, Morocco) Using Hydrochemistry, Multiple Isotopic Tracers, and the Geographical Information System (GIS)
Authors: Nouayti Nordine , Cherif El Khalil , Algarra Manuel , Pola Mᵃ Luisa , Fernández Sara , Nouayti Abderrahim , Esteves da Silva Joaquim C. G. , Driss Khattach , Samlani Nouha , Mohamed Hilali , Azzirgue El Mustapha , Krawczyk Dorota Anna , Rodero Antonio
Published: February 2022

The chemical characterization of the Ghis-Nekor groundwater has become a concern of many researchers in Morocco. It is a crucial indicator for the environment situation and the socioeconomic development of this Moroccan region. Indeed, it helps decisionmakers carry out conscious and sustainable management. For this reason, 20 samples of the Ghis-Nekor aquifer were examined in terms of physicochemical parameters such as pH, temperature, electrical conductivity (EC), and total alkalinity (Alk), major cations–anions (Ca2+, Mg2+, Na+, K+, HCO3−, Cl−, SO42−, NO3−, and TDS), isotopic elements (δ18O, δ2H, and δ13C), and concentrations of Br and Sr anions in 2020. Furthermore, spatial data analysis with a geographic information system (GIS) using the ArcGis software (Redlands, California, USA). Indeed, static maps show significant water quality information that helps characterize the groundwater of the study area. The spatial analysis by the GIS indicates that except the EC (from 2630 to 6950 mS/cm), all the physical parameters showed standard concentration values in most of the samples. A significant concentration above the Moroccan norm of groundwater quality for sodium (Na+) from 264.3 to 1500 mg/L, chlorides (Cl−) concentrations from 408.3 to 1510 mg/L, SO42− from 313.1 to 999.2 mg/L, and bicarbonate (HCO3−) from 283.7 to 679.8 mg/L was observed, while all the points exceeded the recommended standards norm for SO42−. Most of the points met the potability standards for potassium (K+). In terms of the isotopic elements, the concentration values of δ18O were from −3.92‰ to –5.60‰, while the δ2H concentration values varied between −28.67‰ and −39.99‰. The analysis revealed values of carbon isotope δ13C ranging between −3.15‰ and −8.61‰, thus suggesting that the origin of the carbon is mineral, mainly deriving from calcite dissolution. The analysis of the bromide and strontium contents made it possible to discriminate the origin of the salinity anomalies. The Cl/Br, Br/Cl, and Sr/Ca molar ratios distinguished the areas of influence of geological setting (saliferous facies outcrops) or anthropogenic effect (wastewater). The results of the analysis shed light on factors of contamination, which are as follows: urban zones (Imzourene, Ait Youssef, and Souani) and agricultural activities. Therefore, the use of these waters could pose a risk to the health of humans and animals. Similarly, the GIS is a practical and effective tool for the Ghis-Nekor groundwater quality diagnostics and could help decisionmakers establish solutions.
On the use of laser therapy in dentistry
Authors:   National Medical Research Center for Rehabilitation and Balneology of the Ministry of Health of Russia, Peoples’ Friendship University of Russia (FSAEI HE RUDN), Moscow, Kulikova Nataliya Gennadievna , Zhilokov Zaur Gidovich ,   Clinic «Videntis», Peoples’ Friendship University of Russia (FSAEI HE RUDN), Moscow, Tkachenko Albina Sergeevna ,   Peoples’ Friendship University of Russia (RUDN University), Chkheidze Tinatin ,   Clinic «Videntis», Moscow,
Published: February 2022

The aim of the research: to optimize the prevention of dental complications by using electromagnetic low-intensity laser radiation (LILR) techniques on dental and periodontal tissues. Research methods. In 138 dental patients, a clinical and functional assessment of the dental apparatus was carried out, dental indices were studied, the results of vascular endothelial parameters (VEGF-A, sVEGF-R1, sVEGF-R2) and immune parameters (FNF, TNF, IFN-γ, neutrophils) of blood serum (solid-phase enzyme immunoassay with a standard set), as well as VAS pain syndrome parameters were analyzed before/after laser therapy of different wavelength, mode and range (red, infrared). Results. The study made it possible to assess the effectiveness of treatment with LILR with one wavelength and in combination of different lengths of laser radiation as independent factors of preventive exposure in dentistry patients. After applying the techniques of transcanal treatment, dental periapical tissues were treated with laser radiation, including root canals (difficult teeth roots), using the C11 attachment from the «Lazmik-01» device. The study used a modulated red spectrum of LILR in continuous and pulsed mode (l = 635 nm) and an infrared pulsed spectrum (l = 904 nm) in a continuous mode with a sequential exposure to red (l = 635 nm) pulsed and infrared continuous laser radiation (l = 904 nm). Emphasis was placed on pain syndrome, vascular endothelial and immune shifts in dental and periodontal tissues before/after using laser therapy in dental patients. Conclusion. The combination of the red spectrum of LILR in pulsed mode (l = 635 nm) with a sequential exposure to infrared laser radiation (l = 904 nm) in continuous mode provides high vascular endothelial responses in the dental and periodontal tissues of the dental apparatus, and the use of red-spectrum laser radiation in continuous mode (l = 635 nm) in dental patients provides antimicrobial and sanitizing effects, including at the level of the root canals, which is more significant than after the use of infrared laser radiation in pulsed mode, when analgesic results are higher.
Current requirements for inventory in healthcare organizations
Authors:   Financial University under the Government of the Russian Federation, Moscow, Dombrovskaya E.N.
Published: February 2022

The article discusses organizational and methodological aspects of the inventory in health care organizations. The features of the inventory results are presented for medical organizations belonging to public sector organizations. The issue of the article is particularly relevant in connection with the introduction of a number of federal accounting standards for public sector organizations. Based on the review of the existing regulatory framework, the procedure for conducting an inventory, reflecting its results in accounting and testing assets for impairment during the inventory was considered. The article was prepared taking into account the explanations contained in numerous Letters of the Ministry of Finance regarding the issues of inventory in public sector organizations.
Problems and prospects of development of the supplier portal in the public procurement system
Authors:   Plekhanov Russian University of Economics, Zhukova A.O. , Prodanova N.A. ,   Plekhanov Russian University of Economics
Published: February 2022

Digitalization of public procurement activities, increased efficiency, structured information in electronic information systems. The use of tools gives them the opportunity, regardless of presence, to take part in the procurement process, choose the best offer for the use of “price-quality” and get a reliable partner based on available, relevant, and reliable information, thus improving the quality of the model of interaction between the supplier and the customer. But, despite the automated processes, which, on the one hand, allow minimizing the workload at all stages of procurement procedures, there are also problems using the implementation and use of online services in procurement procedures. The authors of the article tried not only to systematize these problems, but also to offer several recommendations for improving the work of the supplier portal as a whole.
WORKSHOP BODY MAPPING UNTUK MENINGKATKAN SELF-ESTEEM PADA ORANG DENGAN HIV (ODHIV)
Authors: Hartono Hartono
Published: February 2022

As of March 2019 there were 338,363 reported cases of people infected with HIV in Indonesia. PLHIV experiences challenges physically and mentally due to stigma from themselves and society. The purpose of this study was to determine the effect of the implementation of body mapping workshop intervention in increasing self-esteem on PLHIV. This study used a quasi-experimental one group pretest-posttest design. The research subjects were 30 People Living with HIV who were recruited by using purposive sampling technique. Pretest and posttest in the form of self-esteem questionnaires were given to participants before and after the workshop to collect the required data. Then, the data were analyzed by using the paired sample t-test. The results of the study showed that there was no effect of body mapping workshop in increasing self-esteem among PLHIV.
GAMBARAN PENGETAHUAN IBU TENTANG PEMANFAATAN BUKU KESEHATAN IBU DAN ANAK (KIA) DI KELURAHAN WANASARI RW. O13 KABUPATEN BEKASI
Authors: Ning Karminingsih , Latifah Latifah , Saputri Febriyanti Ade
Published: February 2022

Masih rendahnya pemanfaatan buku KIA masih terkendala oleh rendahnya pengetahuan dan sikap ibu tentang manfaat dari buku KIA dan sebagian ibu juga menganggap hal-hal yang berhubungan dengan buku KIA hanya sekedar buku catatan pemeriksaan (Yayu, dkk,2015).4 Tujuan penelitian ini adalah untuk mengetahui gambaran pengetahuan dan pemanfaatan Buku Kesehatan Ibu dan Anak (KIA) di Kelurahan Wanasari Rw.013 Kabupaten Bekasi tahun 2020. Variabel independen nya adalah pengetahuan dan variabel dependen nya adalah pemanfaatan buku KIA. Metode penelitian yang digunakan adalah metode deskriptif dengan pendekatan potong lintang . Sampel penelitian ini adalah semua ibu yang mempunyai balita di Kelurahan Wanasari RW. 013 pengambilan sampel dilakukan dengan teknik total sampling dengan responden dalam kriteria inklusi berjumlah 30 responden.pengambilan data menggunakan data primer. Analisis data meliputi univariat dengan melakukan uji distribusi frekuensi. Hasil penelitian menunjukan bahwa berdasarkan karakteristik yaitu usia yang lebih banyak 26-30 tahun sebanyak 15 responden (50,0%). Berdasarkan karakteristik  pendidikan adalah pendidikan rendah (tamat SD, tamat SMP) sebanyak 17 responden (56,7%). Berdasarkan menurut karakteristik pekerjaan yaitu yang tidak bekerja sebanyak 19 responden (63,3%). Berdasarkan Pengetahuan ibu yaitu berpengetahuan cukup sebanyak 12 responden (40,0%). Dan untuk pemanfaatan buku KIA sebanyak 19 responden (63,3%). Kesimpulannya di Kelurahan Wanasari RW.013 tahun 2020 responden memanfaatkan buku KIA dan memiliki pengetahuan dengan baik.
Analisis Resiko Kecelakaan Kerja di PT Jaya Beton Indonesia dengan Metode HIRARC (Hazard Identification Risk Assessment and Risk Control)
Authors: Amanda Prasetyo
Published: February 2022

PT. Jaya Beton Indonesia merupakan perusahaan yang bergerak di bidang industri dan infrastruktur yang memproduksi pengolahan hasil beton. Masalah keselamatan dan kesehatan kerja (K3) merupakan salah satu perhatian utama di PT. Jaya Beton Indonesia dikarenakan masih tingginya jumlah kecelakaan selama kurun waktu 3 tahun terakhir. Terjadinya kecelakaan dan penyakit akibat kerja tentu saja menjadikan masalah yang besar bagi kelangsungan sebuah perusahaan. Berdasarkan permasalahan tersebut penelitian ini menggunakan metode Hazard Identification Risk Assessment and Risk Control (HIRARC), dengan melakukan identifikasi bahaya (hazard identification), penilaian risiko (risk assessment) dan pengendalian risiko (risk control) yang bertujuan untuk mengidentifikasi potensi kecelakaan kerja yang terjadi sehingga dapat dilakukan pencegahannya. Hasil penelitian basic risk didapatkan 7 risiko (25%) berada pada kategori priority 3, 16 risiko (57%) pada kategori substantial, 3 risiko (11%) pada kategori priority,2 risiko (7%) Hasil penelitian existing risk didapatkan 12 risiko (43%), dan pada katagori priority 3  12 risiko (43%), sebanyak 3 risiko substantial 3 (11%) dan 1 risiko priority  (3%). Pengendalian risiko yang diusulkan adalah melakukan pemasangan rambu-rambu safety sign ditempat yang mudah dilihat disetiap area kerja, melakukan sosialisasi mengenai K3, terutama dibagian yang berpotensi bahaya dan risiko yang ada di tempat kerja dan menegakkan disiplin dalam penggunaan Alat Pelindung Diri (APD).
As cheias do rio Mondego e as soluções que tardam a implementar
Authors: Alves Freire Diana Filipa , Antunes do Carmo José Simão
Published: February 2022

São indiscutíveis as vantagens decorrentes da criação de um plano de água na cidade de Coimbra para atividades turísticas (navegação), práticas náuticas (vela, remo, canoagem) e fruição lúdica das margens. Contudo, a construção do açude-ponte modificou as condições de equilíbrio, ou quase-equilíbrio, pré-existentes, nomeadamente através da retenção do material sólido na albufeira. Para além dos prejuízos decorrentes do não usufruto pleno da albufeira, as sucessivas cheias do rio Mondego têm demonstrado que não é ambiental e economicamente sustentável a manutenção de cotas elevadas do leito do rio na zona da albufeira. Neste trabalho analisam-se as causas e consequências da cheia mais recente, ocorrida em dezembro de 2019. Paralelamente, é proposta a construção de uma bacia de sedimentação a montante de Coimbra
Remote sensing based tools to assess risk in rice agriculture
Authors: Pedroso de Lima Isabel , Gerardo Jorge Romeu , Pedroso de Lima João
Published: February 2022

In rice growing, production risk is strongly dependent on the availability of fresh water. The contribution of remote sensing observations in identifying the conditions under which rice is cultivated, particularly throughout the growing season, can be instrumental in water and crop management. This work discusses the usefulness of different remote sensing products, of different spatial resolutions, to describe the local rice growing conditions in the Lower Mondego region, aiming to enhance the use of these tools as a support element in irrigation management.
A problemática dos sem-abrigo: conceito(s) e dinâmicas de causalidade
Authors: Manuel Lúcio José , Marques Filomena
Published: February 2022

A problemática dos sem-abrigo tem vindo progressivamente a interessar a comunidade académica nomeadamente nas áreas das ciências sociais e humanas. O presente artigo insere-se nesta renovada atenção no que às realidades da população que não tem habitação permanente diz respeito. A análise encontra-se dividida em três partes fundamentais, a saber: num primeiro momento, abordaremos os domínios de conceptualização do fenómeno dos sem-abrigo e, seguidamente, proporemos um percurso analítico com enfâse nas dinâmicas de causalidade e visão ecológica sobre a realidade multidimensional do não acesso a soluções permanentes no quadro da habitação.
Marketing Territorial na Sustentabilidade Económica e Ambiental: o caso da Mata do
Buçaco
Authors: Simões Paulo
Published: February 2022

A mata do Buçaco pode ser um instrumento para o desenvolvimento local, dado que se
encontra inserida num complexo termal de reconhecida qualidade das suas águas, uma
gastronomia regional e com um património significativo de interesse nacional, o que se
traduz em várias oportunidades e possibilidades. É incontornável o potencial que o
Buçaco detém para responder às novas conceções da prática turística nomeadamente na
alteração nos hábitos de consumo. Neste caso de estudo identifica-se, também as
principais potencialidades que constituem per si atividades de desenvolvimento
sustentável para a região. As potencialidades do Buçaco deverão ser enquadradas num
modelo de gestão que coloque os seus interesses em primeiro lugar. Foi por isso,
importante resumir um modelo estratégico, pois os modelos até aqui adotados precisão de
se ajustar aos novos desafios.
2021: um tempo para revisitação da gestão do risco e de crises
Authors: Betâmio de Almeida António
Published: February 2022

Em tempo de pandemia histórica, e no âmbito de uma obra muito particular, o autor
apresenta uma síntese que constitui uma reflexão crítica relativamente ao Risco,
conceito, avaliação e gestão do risco e de crises. Uma revisitação em 2021, em forma de
meta-análise, do “estado da arte” e das tendências actuais. Uma apresentação de desafios
epistemológicos colocados ao conjunto de conceitos e metodologias que estruturam
teoricamente o tipo de gestão referido. Um questionamento também da interacção com a
sociedade contemporânea em tempo de uma crise. Esta análise tem por objectivo
fundamental proporcionar pistas futuras de reflexão e estudo e constitui um ensaio de
carácter filosófico.
A problemática dos riscos costeiros no âmbito do Turismo Costeiro e Marítimo: o
caso do município de Odemira
Authors: Velho Gouveia José A. , Morais de Brito Mónica
Published: February 2022

A competividade turística dos territórios decorre da conjugação de uma série de
fatores, materiais e imateriais, entre os quais a segurança, que, na sua
multidimensionalidade, tem vindo a assumir especial relevância. O Turismo Costeiro e
Marítimo é um produto considerado estratégico para o desenvolvimento turístico
sustentável dos territórios junto ao mar, sendo os riscos costeiros um dos aspetos que
influenciam a perceção de segurança da sua procura turística, efetiva e potencial. Neste
trabalho territorializa-se esta temática, constituindo-se o Município de Odemira como
caso de estudo. A partir da caracterização do território, e com base num conjunto de
entrevistas a diferentes atores relacionados com a temática, define-se o perfil de
segurança do Município, uma ferramenta que poderá nortear a ação futura das entidades
públicas e privadas.
Emergency teams in their voice (PSP & GNR) factors of risk and
resilience
Authors: Diego Gonçalves Carmen
Published: February 2022

Giving direct voice to the participants in this study, results of research
conducted with elements of emergency teams in the North of Portugal - Public Security
Police (PSP) and National Republican Guard (GNR) are presented. Using the focus group
methodology, stress factors were identified in the face of emerging situations and / or
cumulative exposure to potentially traumatic events, thus giving visibility to
protective factors. The results correspond to a partial analysis of the data collected
in this investigation, with longitudinal methodological objectives.
AHSCs as Health Policy Transfer: Some Emergent Evidence From Australia Comment on "Academic Health Science Centres as Vehicles for Knowledge Mobilisation in Australia? A Qualitative Study"
Authors: Ferlie Ewan
Published: February 2022

This commentary discusses Edelman et al 2020’s recent exploratory study of the early development of 4 Academic Health Services Centres (AHSCs) in Australia. AHSCs were originally invented in the United States, but have then diffused to the United Kingdom and Canada over the last decade or so and now to Australia so they are a good example of health policy transfer. They are dedicated to advancing more speedy knowledge translation (KT)/mobilization (‘from bench to bedside’) and also the more effective commercialization of scientific inventions. The commentary argues some interesting if preliminary findings are identified in their study. Its limitations will also be considered. Finally, suggestions for future research are made, including more cross national and comparative studies.
The Roles of Regional Organisations in Strengthening Health Research Systems in Africa: Activities, Gaps, and Future Perspectives
Authors: Jones Catherine M. , Sobngwi-Tambekou Joëlle , Mijumbi Rhona M. , Hedquist Aaron , Wenham Clare , Parkhurst Justin
Published: February 2022

Background: Regional cooperation on health in Africa is not new. The institutional landscape of regional cooperation for health and health research, however, has seen important changes. Recent health emergencies have focussed regional bodies’ attention on supporting aspects of national health preparedness and response. The state of national health research systems is a key element of capacity to plan and respond to health needs – raising questions about the roles African regional bodies can or should play in strengthening health research systems. Methods: We mapped regional organisations involved in health research across Africa and conducted 18 interviews with informants from 15 regional organisations. We investigated the roles, challenges, and opportunities of these bodies in strengthening health research. We deductively coded interview data using themes from established pillars of health research systems – governance, creating resources, research production and use, and financing. We analysed organisations’ relevant activities in these areas, how they do this work, and where they perceive impact. Results: Regional organisations with technical foci on health or higher education (versus economic or political remits) were involved in all four areas. Most organisations reported activities in governance and research use. Involvement in governance centred mainly around agenda-setting and policy harmonisation. For organisations involved in creating resources, activities focused on strengthening human resources, but few reported developing research institutions, networks, or infrastructure. Organisations reported more involvement in disseminating than producing research. Generally, few have directly contributed to financing health research. Informants reported gaps in research coordination, infrastructure, and advocacy at regional level. Finally, we found regional bodies’ mandates, authority, and collaborations influence their activities in supporting national health research systems. Conclusion: Continued strengthening of health research on the African continent requires strategic thinking about the roles, comparative advantages, and capability of regional organisations to facilitate capacity and growth of health research systems.