bluuebunny/crossref_metadata_2025 huggingface dataset:
АЗОТ В ПОЧВАХ СТЕПНОГО ПОВОЛЖЬЯ И ИХ НИТРИФИКАЦИОННАЯ АКТИВНОСТЬ
Authors: Пронько Виктор Васильевич , Пронько Нина Анатольевна
Published: December 2024

Изучено содержание азота в наиболее распространенных типах почв степного Поволжья (включая увлажненную и сухостепную подзоны). Объекты исследований: темно-серая лесная почва, чернозем (подтипы - выщелоченный, обыкновенный и южный), каштановая террасовая почва. Установлено снижение содержания общего азота в слое 0-30 см при переходе от чернозема выщелоченного (4287 мг/кг) к каштановой почве (1013 мг/кг). Доля минерального азота (сумма нитратного и аммонийного) от его валовых запасов самой высокой оказалась в почвах сухостепной подзоны: в черноземе южном - 3,3%, каштановой террасовой - 3,6%. Максимальная нитрификационная способность отмечена у чернозема выщелоченного (61,6 мг/кг N-NO3), минимальная - у каштановой террасовой (0,8 мг/кг N-NO3). Добавление карбамида в образцы почвы при их компостировании сильнее всего повысило нитрификационную способность чернозема выщелоченного (в 5,4 раза по сравнению с неудобренными образцами). Добавление экспериментального гуминового препарата оказало разнонаправленное влияние на процессы нитрификации при компостировании.

The content of nitrogen in the most common types of soils of the steppe Volga region (including the wet and dry steppe subzones) was studied. Objects of the research: dark grеy forest soil, chernozem (leached, typical and southern subtypes), chestnut terraced soil. A decrease in the content of total nitrogen in the 0-30 cm layer was stated when moving from leached chernozem (4287 mg/kg) to chestnut soil (1013 mg/kg). The share of mineral nitrogen (the sum of nitrate and ammonium) of its gross reserves was the highest in the soils of the dry steppe subzone: in the southern chernozem there was 3.3%, chestnut terrace 3.6%. The maximum nitri cation capacity was noted for leached chernozem (61.6 mg/kg N-NO3), the minimum for chestnut terrace soil (0.8 mg/kg N-NO3). The incorporation of urea to soil samples during their composting increased the nitri cation capacity of leached chernozem the most (by 5.4 times compared to unfertilized samples). The incorporation of an experimental humic-based product showed a multidirectional e ect on the processes of nitri cation during composting.
ИСПОЛЬЗОВАНИЕ РЕСУРСОВ ТОРФА И САПРОПЕЛЯ В СЕЛЬСКОМ ХОЗЯЙСТВЕ НЕЧЕРНОЗЕМНОЙ ЗОНЫ РОССИИ: СОСТОЯНИЕ ВОПРОСА И ПЕРСПЕКТИВЫ
Authors: Анисимова Татьяна Юрьевна
Published: December 2024

Россия обладает огромными ресурсами торфа и сапропеля - сырья природного происхождения для производства органических удобрений, применение которых обеспечивает повышение биологической и энергетической емкости агроценозов, воспроизводство плодородия почв. В статье представлены данные по ресурсам торфа и сапропеля в Нечерноземной зоне и в России в целом, а также показаны перспективные направления их использования в сельском хозяйстве.

Russia has huge resources of peat and sapropel raw materials of natural origin for production of organic fertilizers, the use of which provides an increase in the biological and energy capacity of agrocenoses, the reproduction of soil fertility. The article presents data on the resources of peat and sapropel in the Non-Chernozem zone in particular and in Russia on the whole as well as shows the promising directions of their use in agriculture.
ФИЗИЧЕСКИЕ СВОЙСТВА СУБСТРАТОВ ДЛЯ КРОВЕЛЬНОГО ОЗЕЛЕНЕНИЯ
Authors: Корытина М.А. , Фаустова Е.В. , Гончаров В.М.
Published: December 2024

Технологии озеленения кровли зданий – «зеленой крыши» – требуют создания оптимальных по агрофизическим свойствам субстратов. В работе представлены результаты исследования комплекса физических свойств субстратов двух опытных площадок «зеленой» крыши Оранжерейного корпуса МГУ, а именно, плотности, пористости, водоудерживающей способности, влаго- и температуропроводности. Субстраты представляют собой смеси, содержащие в различных пропорциях речной песок, верховой торф, кокосовое волокно и агроперлит. Они характеризуются высокими значениями наименьшей влагоемкости (84,7% и 88,5% от объема), плотность засыпки составляет 1,14 г/см3 для субстрата 1 и 0,87 г/см3 для субстрата 2, плотность твердой фазы 2,30 и 2,48 г/см3 , соответственно. Высокая влагоудерживающая способность органических компонентов – кокосового волокна и торфа – характеризует запас легкодоступной для растений влаги. Расчет элементов водно-воздушного режима субстратов дал возможность оценить влагообеспеченность растений.

Technologies for greening the roof of buildings – the «green roof» – require the creation of nutrient substrates that are optimal in terms of agrophysical properties. Studies of the complex of physical properties of substrates (density, porosity, moisture conductivity and water-retaining capacity, thermal diffusivity) were carried out on the «green roof» of the greenhouse building of Moscow State University. Substrates containing various proportions of river sand, high-moor peat, coconut fi ber and agroperlite were taken as objects. In general, mixtures are characterized by low total density and density of the solid phase, high values of the lowest moisture capacity. Hydrophysical studies of the components made it possible to calculate the elements of the water-air regime to assess the moisture supply of plants. The high water-holding capacity of organic components – coconut fi ber and peat – characterizes the supply of moisture readily available to plants, and low thermal diffusivity prevents the substrate from freezing in winter and drying out in summer.
Анализ данных определения содержания органического углерода разными методами
Authors: Самсонова В.П. , Кондрашкина М.И.
Published: December 2024

На основании опубликованных данных [Безуглова и др., 2014, 2015] проводится сопоставление двух методов определения содержания почвенного углерода – метода высокотемпературного каталитического сжигания на анализаторе общего органического углерода TOC-L CPN Shimadzu, и косвенным методом Тюрина в модификации Симакова. Показано, что статистической моделью аналитических данных может быть смесь нескольких статистических распределений, обусловленных разными механизмами формирования результатов. Выдвинуто предположение, что ключевыми факторами выступают пробоподготовка лабораторных проб и особенности органического углерода в анализируемых пробах. Уменьшение аналитической ошибки может быть достигнуто путем двойных повторностей.

Based on the published data (Bezuglova et al., 2014, 2015), a comparison of two methods for determining the soil carbon content is carried out – the method of high-temperature catalytic combustion on the TOC-L CPN Shimadzu total organic carbon analyzer, and the indirect Tyurin method in Simakov’s modifi cation. It is shown that the statistical model of analytical data can be a mixture of several statistical distributions due to diff erent mechanisms of formation of results. It has been suggested that the key points may be the sample preparation of laboratory samples and the features of organic matter in the analyzed samples. Reducing analytical error can be achieved by double repetition.
Особенности формирования урожайности зерна чечевицы в агроэкологических условиях южной лесостепи Западной Сибири
Authors: Саурбаев А.Ж. , Поползухина Н.А. , Омельянюк Л.В.
Published: December 2024

Представлены результаты трехлетнего (2020–2022 гг.) изучения особенностей формирования урожайности зерна и элементов ее структуры у различных сортов чечевицы (Lens culinaris Medik.) в условиях южной лесостепи Западной Сибири. Оценка сортов чечевицы различного эколого-географического происхождения в контрастных условиях выращивания позволила выделить наиболее адаптивные к условиям южной лесостепи Западной Сибири – Инвизибл (Канада) и стандарт Нива 95, которые характеризовались наибольшим уровнем урожайности зерна. Урожайность сорта Инвизибл обеспечивалась комплексом элементов структуры – высотой и массой растений, числом бобов и семян, массой семян на одном растении, а также массой 1000 семян. Для сорта чечевицы Нива 95 определяющими урожайность показателями были число семян на растении и масса 1000 семян.

The article presents the results of a 3-year (2020–2022) study of the formation of grain yield and elements of its structure in various varieties of lentils (Lens culinaris Medik.) in the conditions of the southern forest-steppe of Western Siberia. The purpose of the work is to identify the features of the formation of grain yield and elements of its structure in different varieties of lentils in contrasting agro-ecological conditions of cultivation. Evaluation of lentil varieties of different ecological and geographical origin in contrasting growing conditions made it possible to identify the most adaptive to the conditions of the southern forest-steppe of Western Siberia – a variety from Canada ‘Invisible’ and a variety-standard ‘Niva 95’, which were characterized by the highest level of grain yield. The yield of the Invisible variety was provided by a complex of structural elements – the height and weight of plants, the number of beans and seeds, the weight of seeds per plant, and the thousand-seed weight. For the lentil variety ‘Niva 95’, the determining yield indicators were the number of seeds per plant and the thousand-seed weight.
МЕТОДЫ МОДЕЛИРОВАНИЯ УРОЖАЙНОСТИ СЕЛЬСКОХОЗЯЙСТВЕННЫХ КУЛЬТУР: ОБЗОР
Authors: Шарый П.А. , Шарая Л.С. , Рухович О.В. , Шкуркин С.И.
Published: December 2024

В обзоре рассматриваются подходы к моделированию оценки и прогнозирования урожайности сельскохозяйственных культур. Описаны имитационные и статистические модели, а также методы использования спутниковых данных. Отмечены особенности и возможности каждого из подходов, их ограничения, а также некоторые полученные с их помощью результаты. Имитационные модели удобны для прогнозов на будущее, но используют большое количество параметров, часто недоступных, поэтому их заменяют субъективно выбранными, что снижает качество моделирования. Статистические модели напрямую оценивают неопределенность предсказаний с помощью коэффициента детерминации, но при использовании статистически не вполне независимых переменных их интерпретация затрудняется. Использование спутниковых данных совместно с климатическими и рельефом дает возможность изучать большие регионы, но современное состояние дистанционного зондирования не позволяет различать разные виды культур, идентифицируя лишь озимые и яровые. Объединение спутниковых наблюдений с имитационными или статистическими моделями позволяет осуществлять прогнозы урожайности в больших регионах, но лишь в предположении постоянства во времени количества вносимых удобрений и агротехнической обработки.

Approaches are considered to model estimates and forecasts crop production. Process-based and statistical models are reviewed as well as methods that use satellite data. Specifi c features and possibilities of each approach are considered, their restrictions, and some obtained with them results. Process-based models are useful for forecasts, but they use large number of parameters that are often not available, so they are replaced by subjectively chosen ones, which diminishes the model’s quality. Statistical models directly evaluate prediction uncertainty, but may use variables that are close to dependent ones, what may make interpretation more complex. The use of satellite data together with climatic data makes it possible to study large regions, but the current state does not permit to distinguish species identifying only winter and spring cultures. Using in addition process-based or statistical models allows carrying out predictions of crop production in large regions, but assumes in forecasts the constant in time fertilizers and agrotechnical treatments.
Влияние праймирования гуминовыми веществами семян пшеницы на появление и развитие проростков в условиях засухи и переувлажнения
Authors: Николаева А.А. , Филиппова О.И. , Куликова Н.А.
Published: December 2024

Изучено влияние гуминовых веществ (ГВ) как праймирующих агентов на появление и развитие проростков пшеницы мягкой Triticum aestivum L. при недостаточном и избыточном увлажнении в лабораторных условиях. Рабочую концентрацию ГВ (2 г/л) выбирали на основании биотестирования методом проростков с моделированием оптимальных условий (вода) и водного дефицита (раствор полиэтиленгликоля с молекулярной массой 6000 г/моль в концентрации 150 г/л). В ходе лабораторно-вегетационного эксперимента оценивали динамику появления всходов, всхожесть, параметры флуоресценции хлорофилла, содержание пигментов и водный дефицит в листьях, длину и массу надземной части растений. Проведенные эксперименты продемонстрировали, что в диапазоне почвенной влажности 40–100 % от наименьшей влагоемкости (НВ) праймирование ГВ увеличивает итоговую всхожесть в среднем в 1,3 раза, содержание каротиноидов в 1,1 раза и снижает коэффициент α, отражающий способность растений использовать свет в условиях низкой освещенности, в 1,3 раза. В условиях недостаточной влажности (40 % от НВ) праймирование ГВ способствовало снижению водного дефицита в листьях. Среднее увеличение надземной биомассы в указанном диапазоне влажности вследствие праймирования ГВ составило 1,2 раза.

The effect of humic substances (HS) as priming agents on the emergence and development of seedlings of common wheat Triticum aestivum L. was studied under drought and excessive water conditions in laboratory experiments. The working concentration (2 g/l) was chosen based on the results of biotesting by the method of seedlings with modeling of optimal conditions (water) and water deficit (polyethylene glycol solution with a molecular weight of 6000 g/mol at the concentration of 150 g/l). During the laboratory-vegetation experiment emergence of seedlings, germination, parameters of chlorophyll fluorescence, pigments content and water deficit in leaves, length and mass of the aerial part of plants were evaluated. Dry seeds and seeds primed with water were used as controls. The experiments performed have shown that in the soil moisture range of 40–100 % of the lowest water capacity, HS priming increases the final germination by an average of 1,3 times, the content of carotenoids by 1,1 times and reduces the coefficient α, which reflects the ability of plants to use light in low light conditions, 1,3 times. Under conditions of 40 % of lowest moisture capacity of the soil, HS priming contributed to a decrease in water deficit in the leaves. Average increase in aboveground biomass, taking into account the observed phenomenon of HS priming 1,2 times.
ИЗМЕНЕНИЯ В КРУГОВОРОТЕ АЗОТА В ПОЧВЕ ПРИ ПРЯМОМ ПОСЕВЕ ЯРОВОЙ ПШЕНИЦЫ И ВНЕСЕНИИ АЗОТНЫХ УДОБРЕНИЙ
Authors: Кизимова Т.А. , Коробова Л.Н.
Published: December 2024

Показана реакция микробного сообщества круговорота азота в черноземе выщелоченном северной лесостепи Приобья на осеннее внесение КАС-32 и гранулированного сернокислого аммония в дозе 60 кг д.в. по стерневому фону под вторую пшеницу в севообороте. Установлено, что жидкое азотное удобрение КАС-32 стимулировало развитие нитрификаторов, азотфиксаторов и микроорганизмов-минерализаторов, использующих органические формы азота, и уменьшало обилие в почве денитрификаторов, связанных с потерями газообразного азота. Совместное внесение КАС-32 и микробиологического препарата Стернифаг, СП обеспечило дополнительный прирост почвенных аммонификаторов в 1,5 раза и уменьшило обилие денитрификаторов в 1,4 раза. Сернокислый аммоний на стерневом фоне положительно повлиял на нитрификаторов и азотфиксаторов. Корреляционная связь урожайности зерна яровой пшеницы при прямом посеве с микробами круговорота азота в черноземе выщелоченном была на уровне сильной и лишь у аммонификаторов оказалась средней силы.

The reaction of the microbial community of the nitrogen cycle in the leached chernozem of the northern forest-steppe of the Ob region to the autumn application of UAN-32 and granular ammonium sulfate at the dose of 60 kg a.i. on the stubble background for the second wheat in the crop rotation was shown. It was found that the liquid nitrogen fertilizer UAN-32 stimulated the development of nitrifiers, nitrogen fixers and mineralizing microorganisms using organic forms of nitrogen, and reduced the abundance of denitrifiers in the soil associated with losses of gaseous nitrogen. The joint application of UAN-32 and the microbiological preparation Sternifag provided the additional increase in soil ammonifiers by 1.5 times and reduced the abundance of denitrifiers by 1.4 times. Ammonium sulfate on a stubble background had the positive effect on nitrifiers and nitrogen fixers. The correlation between the yield of spring wheat grain in direct sowing with the microorganisms of the nitrogen cycle in the leached chernozem was strong and it turned out to be of average strength only with the ammonifiers.
ВЛИЯНИЕ ЛИСТОВЫХ ПОДКОРМОК ГУМИНОВЫМИ УДОБРЕНИЯМИ НА ПРОДУКТИВНОСТЬ ТЫКВЫ МУСКАТНОЙ В САРАТОВСКОМ ЗАВОЛЖЬЕ ПРИ ОРОШЕНИИ
Authors: Корсаков К.В. , Пронько В. В. , Пронько Н.А.
Published: December 2024

На орошаемых темно-каштановых почвах Саратовского Заволжья в 2018–2020 гг. изучали влияние гуминовых удобрений на урожайность и качество плодов тыквы мускатной сорта Гитара. Установлена высокая отзывчивость изучаемой культуры на листовые подкормки растворами удобрений. Самая высокая прибавка урожая в условиях экспериментов в среднем за три года составила 24,6 т/га (43% к контролю). Она получена на варианте с трехкратным использованием листовых подкормок: первая – Reasil Forte Carb-Ca/Mg/B-Amino 1,0 л/га и два опрыскивания Reasil Forte Carb-N-Humic по 2,0 л/га каждый. Гуминовые удобрения оказали положительное влияние на содержание в плодах тыквы сахаров, провитамина А (каротиноидов) и витамина С. Вместе с тем их использование привело к увеличению выноса из почвы азота, фосфора, калия.

The infl uence of humic based fertilizers on the yield and quality of the musky gourd (Cucurbita moschata (Duchesne) Poir.) fruit of Guitar variety was studied on irrigated dark chestnut soils of Saratov Zavolzhye in 2018–2020. High responsiveness of the studied crop to foliar dressing with fertilizers solutions was established. The highest yield increase in the experiments on average over three years was 24.6 t/ha (43% to the control). It was obtained in the variant with a triple use of foliar dressing: the fi rst one was Reasil Forte Carb-Ca-Mg-B-amino 1.0 l/ha and two subsequent sprayings by Reasil Forte Carb-N-Humic 2.0 l/ha each. Humic fertilizers had the positive eff ect on the content of sugars, provitamin A and vitamin C in gourd fruits. At the same time, their use led to an increase in the removal of nitrogen, phosphorus, and potassium from the soil.
ФРАКЦИОННЫЙ СОСТАВ МИНЕРАЛЬНЫХ ФОСФАТОВ ОРОШАЕМЫХ ЛУГОВЫХ И СЕРОЗЕМНО-ЛУГОВЫХ ПОЧВ БАССЕЙНА ฺр. ЧИРЧИК
Authors: Жураев Ш.А. , Баиров А.Ж. , Абдурахмонов Н.Ю. , Нуриддинова Х.Т. , Холматов О.И.
Published: December 2024

Орошаемые почвы Узбекистана являются карбонатными, содержание СО2 карбонатов в этих почвах достигает 10 % и более. На этих почвах широко применяются фосфорные удобрения, но их эффективность не превышает 20% из-за сильной фиксации фосфора в почве. Несмотря на это положение, исследованиям, посвященным изучению фосфатного состояния орошаемых почв Узбекистана, уделяется мало внимания. Целью данной работы было изучение фракционного состава минеральных фосфатов орошаемых луговых и сероземно-луговых почв бассейна р. Чирчик Ташкентской области Узбекистана. Минеральные формы фосфора определены методом Гинзбург-Лебедевой. Результаты исследования показали, что основную часть фосфатов изученных почв составляют минеральные соединения фосфора. Высокое содержание карбонатов в почвах и щелочная реакция среды способствовали преобладанию высокоосновных фосфатов (Са-PIII). Содержание разноосновных фосфатов (Са-PII) значительно меньше высокоосновных (Са-PIII), в то же время содержание Са-PII несколько раз превышает содержание рыхлосвязанных фосфатов (Са-PI). Содержание фосфатов железа (Fe-P) и фосфатов алюминия (Al-P) в несколько раз меньше, чем фосфатов кальция (Са-P).

Irrigated soils of Uzbekistan are carbonate, the content of CO2 carbonates in these soils reaches 10% or more. Phosphorus fertilizers are widely used on these soils, and their effectiveness does not exceed 20% due to the strong fixation of phosphorus in the soil. Despite this provision, little attention has been paid to studies devoted to the study of the phosphate state of irrigated soils in Uzbekistan. The purpose of this study was to study the fractional composition of mineral phosphates of irrigated meadow and gray-earth meadow soils of the Chirchik river basin of the Tashkent region of Uzbekistan. The mineral forms of phosphorus were determined by the Ginzburg-Lebedeva method. The results of the study showed that the main part of the phosphates of the studied soils are mineral compounds of phosphorus. The high content of carbonates in soils and the alkaline reaction of the medium contributed to the predominance of high-base phosphates (Ca-PIII). Content of polybasic phosphates (Ca-PII)significantly less highly basic (Ca-PIII ), at the same time, the content of Ca-PII is several times higher than the content of loosely bound phosphates (Ca-PI ). The content of iron phosphates (Fe-P) and aluminum phosphates (Al-P) is several times less than calcium phosphates (Ca-P).
ИСПОЛЬЗОВАНИЕ ОСАДКОВ ГОРОДСКИХ СТОЧНЫХ ВОД В СЕЛЬСКОМ ХОЗЯЙСТВЕ АФРИКАНСКИХ СТРАН
Authors: Абакар А.У. , Морачевская Е.В.
Published: December 2024

В статье рассматривается проблематика применения осадка городских сточных вод и его использования в аграрном секторе африканских стран. Показано, что неудовлетворительное качество воды отрицательно влияет не только на показатели плодородия, но и приводит к инфицированию сельскохозяйственных культур патогенами, снижает их урожайность и качество продукции. С применением метода SWOT-анализа оценены сильные и слабые стороны, возможности и угрозы применения осадка сточных вод на африканском континенте. Рассмотрены условия его безопасного применения.

In this paper the problems of urban sewage sludge application and its use in the agricultural sector of African countries are considered. It is shown that unsatisfactory water quality negatively aff ects not only fertility indicators, but also leads to infection of crops with pathogens, reduces their yield and product quality. Using the SWOT analysis, the strengths and weaknesses, opportunities and threats of using sewage sludge on the African continent were assessed. The conditions of its safe usage are regarded.
Learning A Hierarchical Graph Autoregression Model for Semi-template Molecular Retrosynthesis
Authors: Yuan Shen , Wang Fanmeng , Wei Zhewei , Zhao Peilin , Li Lanqing , Xu Hongteng
Published: December 2024

As a significant task of pharmaceutical and chemical engineering, molecular retrosynthesis aims at predicting candidate reactants from predefined products. Treating this challenging task as a conditional generative modeling problem, we propose a hierarchical graph autoregression (HGAR) model and its pretraining-assisted multi-task learning paradigm, leading to an effective semi-template molecular retrosynthesis method. Given a product, we first construct a hierarchical graph by connecting the junction tree of its motifs to the atom-level molecular graph. Our HGAR model embeds the hierarchical graph in the motif and atom levels, respectively. The atom-level embeddings are applied to predict reaction centers and derive synthons from the product. The motif-level embeddings are applied to predict motifs and complete the corresponding synthons autoregressive, leading to the target reactants. We first pretrain the model on PCQM4M-LSC and then fine-tune it on the USPTO retrosynthesis datasets, leading to a model with good generalization power. Experiments show that our HGAR outperforms many representative molecular retrosynthesis methods, especially those semi-template ones, indicating its feasibility and effectiveness in practice.
Nuclear Quantum Effects Across Chemical Space
Authors: Webb Michael , Ugur Baris
Published: December 2024

Nuclear quantum effects (NQEs) are important in many physical and chemical processes--particularly those involving lighter nuclei or occurring at low temperatures. Nevertheless, NQEs have been carefully quantified in few systems, such as water, and their importance is rarely considered. Here, using path-integral molecular dynamics, we critically examine NQEs for a range of molecular properties (e.g., density, thermal expansion coefficients, isothermal compressibility, static dielectric constant, and the heat of vaporization) across 87 molecular liquids. We discover substantial NQEs in this broad chemical space, with molar volumes exhibiting differences of up to 5% between classical and quantum treatments; similar magnitudes are revealed in equilibrium isotope effects from deuteration. Using machine learning, we identify that four molecular properties that are readily known or easily computed with classical simulations—density, molar mass, hydrogen density, and thermal expansion coefficient—are strong predictors of NQEs. Further data-driven analysis reveals how molecular factors, such as branching and heteroatom composition, influence intermolecular interactions and fluid stability and thereby affect observed NQEs. This work offers new insights into the relationship between NQEs and molecular chemistry and refines expectations for when rigorous treatment of NQEs is necessary.
Monophthalates of betulinic acid and related pentacyclic triterpenes inhibit efficiently the SOS-mediated nucleotide exchange and impact PI3K/AKT signaling in oncogenic K-RAS4B proteins
Authors: Benary Gerrit E. , Kilgenstein Frank , Koller Sascha , Scherkenbeck Jürgen
Published: December 2024

Betulinic acid and other herbal pentacyclic triterpenes have attracted interest in cancer research as these natural products induce apoptosis and suppress tumor progression. However, the molecular basis of the antitumor effect is still unknown. Here we show that monophthalates of betulinic acid and related triterpenes inhibit GDP/GTP exchange in oncogenic K-RAS4B proteins via the PI3K/AKT downstream cascade. According to a binding model based on molecular modelling, these derivatives act like a molecular glue that stabilizes an unproductive K-RAS4Ballo:SOS complex. This represents a new mode of action and could be an attractive route for targeting RAS-related cancers.
Pendidikan Karakter Menurut Guru Haji Ismail Mundu
Authors: Piansyah Reno
Published: December 2024

Penelitian ini bertujuan untuk menjabarkan dan membahas Pendidikan karakter menurut  Guru Haji Ismail Mundu, peneliti menggunakan metode konten analisis yang terdapat pada karya-karya beliau. Hasil penelitian ini menunjukkan terdapat beberapa prinsip dan nilai Pendidikan karakter menurut Guru Haji Ismail Mundu yaitu 1) nilai religius, Guru Haji Ismail Mundu menganjurkan seseorang untuk berusaha dalam belajar Agama dan Ilmu yang berkaitan dengan Ibadah. 2) larangan fitnah dan mengumpat. 3) sikap dermawan, pada sikap ini Guru Haji Ismail Mundu mengajak untuk gemar bersedekah dari harta yang telah dititipkan Allah Ta’ala SWT. 4) Guru Haji Ismail Mundu melarang untuk bersifat tamak dan rakus
Fluid Resuscitation and Trauma Management: Permissive Hypotension, Restricted Volume, and Beyond
Authors: Rahmadian Rizki , Evlin Margaretha Ruth , Ariliusra Zikril , Milfiadi Handyka
Published: December 2024

Uncontrolled hemorrhagic shock is responsible for 40% of deaths among those under the age of 35, making it the primary cause of mortality in this age group. An optimal fluid therapy strategy can restore tissue perfusion and oxygenation in trauma patients. However, excessive fluid resuscitation can result in glycocalyx shedding, which leads to globally increased permeability syndrome, leading to complications such as changes in tissue perfusion, abdominal compartment syndrome, and respiratory distress syndrome. Permissive hypotension is a resuscitation strategy that aims to maintain systolic blood pressure below the normal threshold. Restricted volume replacement or restricted fluid resuscitation is a resuscitation principle that limits the amount of fluid used to prevent the worsening of diluted coagulopathy, hypothermia, and acidosis. This review article aims to discuss the recent concept of fluid therapy in trauma and to connect the understanding of fluid therapy in trauma with related topics such as trauma-induced coagulopathy and damage control resuscitation.
Research on Hainan Sports Tourism Experience Behavior Based on the Influence of Network Text
Authors: Guan Hongguo
Published: December 2024

This study focuses on the influence of online texts on Hainan’s sports tourism experience behavior, aiming to explore the specific impact of online texts on Hainan’s sports tourism experience behavior and provide a reference for promoting the development of Hainan’s sports tourism. The study used methods such as text analysis to collect and analyze textual content related to Hainan sports tourism on the Internet. The research results indicate that online text has a significant impact on tourists’ travel decisions, destination selection, participation in sports events, and experience satisfaction. Positive online text can attract more tourists, while negative text may cause tourists to hesitate or give up. The research conclusion is that online text significantly affects the experience behavior of sports tourism in Hainan. Relevant departments and enterprises should attach importance to the role of online text, actively manage and guide online public opinion, improve service quality and tourist experience, and promote the sustainable development of sports tourism in Hainan.
Research on Innovation in Rural Public Infrastructure Management under the Background of Rural Revitalization
Authors: Ni Qizhen
Published: December 2024

To promote the sustainable development of rural public infrastructure management in the context of rural revitalization, this study focuses on management systems, funding strategies, and maintenance capacities. It analyzes existing challenges in these areas, such as underdeveloped management structures, limited financial investment, and weak maintenance capacities. Through a multi-stakeholder approach led by the government, involving social participation and market-driven initiatives, an efficient management system is established to ensure high facility utilization and service quality. The analysis indicates that a well-developed institutional framework and a robust multi-level funding structure can significantly enhance infrastructure management efficiency, providing strong support for rural development.
Tracing the Cultural Genes of the Great Striving Spirit of the Chinese Nation
Authors: Sun Ting
Published: December 2024

The great striving spirit is one of the most important spiritual symbols of the Chinese nation, which has gradually formed through philosophical thinking and historical practice in the long river of history. The great striving spirit originated from Zhouyi, which states that “As Heaven is in constant motion and vibrant, virtuous men should strive continuously for self-improvement.” This indicates the respect and adherence of the ancestors to the laws of cosmic motion. Next, the “Three immortality” of “Li De”, “Li Gong”, and “Li Yan” demonstrate the ideal of striving for a civilized and developed society, with moral cultivation as the fundamental premise. Next, Wang Yangming, a representative figure of the Confucian philosophy of mind, proposed classic propositions such as “the unity of knowledge and action” and “the pursuit of conscience”, he implemented moral cognition and moral practice into daily cultivation and included human transcendence and striving spirit in every detail of life. These precious spiritual treasures have influenced countless people and gathered into a great tide of striving spirit, creating outstanding spiritual and material civilization for the Chinese nation and making tremendous contributions.
A Study to Understand How Visual Communication Supports the Perceived Value of Nonexpert Digital Fashion Investors
Authors: Zheng Fanlong
Published: December 2024

Unlike the traditional fashion market, where there is easy access to the details of fashion manufacturing, such as textiles and functionalities, the digital fashion market, by nature, prevents traditional fashion investors from accessing complex data without the requisite knowledge of virtual asset transactions. To improve the transition period of shifting from physical to digital, this paper studied how design can increase user engagement and how visual communication impacts user behaviors by utilizing perceived value to better understand the potential demands of the users. This paper conducted 2 stages of study with interface designs through a group of participants. This research examined and condensed the most frequently expressed viewpoints to investigate how visual communication might improve consumers’ perceived value. The results aim to assist future visual designers.
Students' Attitudes Towards Dating Violence
Authors: Şahin Osman , Yıldırım Serap , Acar Ecem , Sivuk Derya
Published: December 2024

This study examines students' attitudes towards dating violence with respect to gender in universities. The research was conducted on 392 university students: 270 females and 122 males. Data collection took place during the months of November 2023 through January 2024. The population of the research consisted of a total of 1489 university students studying at Erzincan Binali Yildirim University Health Vocational School in 2023-2024. General, physical, emotional, economic and sexual violence were examined in the research. When the results are examined, males do not support violence (except sexual violence) in any sub-dimension compared to females. Without covariates, the mean sexual violence of females and the mean sexual violence of males are not statistically significant (p;0.05). However, with a small effect of covariates, females do not support sexual violence compared to male individuals. From this evaluation, we can reach some conclusions about healthcare management students' attitudes towards dating violence in Turkey. Also, such rich information will contribute to the theoretical and practical underpinnings of dating violence for developing countries like Turkey.
Supply chain integration and its relationship with the business performance of metal-mechanics small and medium-sized enterprises
Authors: Arellano-Rodríguez Juan Bernardino
Published: December 2024

Small and medium-sized enterprises (SMEs) in Latin America demonstrate productivity levels of 32% and 43%, respectively, when compared to large companies. This lower productivity places them at a disadvantage in accessing the global value chain. According to the OECD/ECLAC (2012), factors that help SMEs improve their business performance include access to knowledge and information (from customers and suppliers) and the implementation of managerial systems, such as supply chain integration (SCI). This research examines the relationship between SCI and the business performance of metal-mechanics manufacturing SMEs in the metropolitan zone of Guadalajara (ZMG), Jalisco, Mexico. The findings indicate that supplier integration, internal integration, and customer integration have a positive and significant impact on business performance.
The influence of digital transformation and implementation barriers on innovation in Brazilian micro, small, and medium enterprises
Authors: Cassaro Edna , Oro Ieda Margarete , Begnini Sérgio , Georges Marcos Ricardo Rosa
Published: December 2024

This study aims to analyze the influence of digital transformation on innovation and the moderating role of barriers to digitalization in this relationship within Brazilian micro, small, and medium enterprises (MSMEs). The sample comprises 731 Brazilian MSMEs. The findings indicate that digital transformation, characterized by digitalization strategies and technology usage, has a positive and significant impact on innovation. Moreover, barriers to digitalization negatively and significantly affect the relationship between digital transformation and innovation, but this effect is observed only in medium-sized enterprises. This study contributes to strategic management practices by providing insights into the role of digital transformation in business innovation. Future research should investigate why barriers to digitalization do not consistently impact the relationship between digital transformation and innovation.
Ensuring the reliability of corrosion and mechanical resistance of pipelines and steel structures of oil and gas complexes
Authors: Zyma Oleksandr , Steblianko Valeriia , Pahomov Roman , Mytrofanov Pavlo
Published: December 2024

The article addresses the issue of ensuring the reliability and durability of steel structures used in oil and gas complexes. Attention is drawn to the need for research and improvement of scientific, technical, and technological developments in the field of corrosion-mechanical resistance of metal structures. The article describes the results of experimental research aimed at analyzing the causes and mechanisms of metal strength loss during operation, and proposes a method for predicting the residual working life of structures. The obtained results make a significant contribution to the development of technical and design measures to enhance the efficiency and reliability of oil and gas complexes
The Philosophical Component of University Education (2010s–mid 2020s)
Authors: Shchelkunov M. D.
Published: December 2024

This article explores the state and progress of philosophical education at Kazan Federal University over the last 15 years. In a brief historical overview, the distinct features of the philosophical curriculum at Kazan University during the pre-revolutionary, Soviet, and post-Soviet periods are identified. The modernization of the university-wide philosophy course for bachelor’s students in the 2020s, focusing on the competency-based approach, is traced. The role of university philosophers in designing and delivering the course “Foundations of the Russian Statehood” is emphasized. The evolution of professional education in the fields of philosophy and religious studies, along with theology related to them, is analyzed. In conclusion, the main challenges faced by the philosophical community in maintaining the relevance of social and humanitarian training for students, as well as in restoring and strengthening the spiritual and moral foundations of university-level philosophy in Russia, are discussed.
The fate of philosophy in Russia as reflected in the works of Kazan University philosophers
Authors: Serebryakov F. F.
Published: December 2024

In this article, Kazan University philosophy, its characteristics and development trends, are analyzed from the perspective of the history of philosophy in Russia. The equivalence of the concepts “history of philosophy in Russia” and “history of Russian philosophy” is questioned and explored using the examples from the “stories” and “essays” written by prominent Russian philosophers such as A.I. Vvedensky, M.N. Ershov, B.V. Yakovenko, N.O. Lossky, and V.V. Zenkovsky. It is shown that they are likely to be equivalent and interchangeable, with the concept “history of Russian philosophy” approached in a broader sense. However, some important distinctions are still observed. When considered in a narrow sense, “Russian philosophy” appears to have certain fundamental, specific characteristics that define it as a specific type throughout its history and determine its unity. The results obtained reveal that some scholars view certain philosophical trends that developed in Russia as foreign or alien to the “spirit of Russian philosophy.” The peculiarities of Russian philosophy are singled out and summarized, and the validity of attempts to obstruct some of its manifestations is discussed. The critical role of university philosophy in the overall history of Russian philosophy is emphasized: it fostered philosophical interest and paved the way for purely philosophical work. Within this framework, Kazan University philosophy is examined.
«Орлове гніздо» Олени Пчілки: текст і контекст
Authors: Пашук (Кицан) Олена
Published: December 2024

The article is devoted to the analysis of Olena Pchilka's unpublished historical poem «Orlove hnizdo». Some printed fragments do not allow us to fully understand the depth of the author's poetic thinking and all the facets of her artistic talent. Therefore, the purpose of the article is to study the history of the poem, its composition, and poetic features. To achieve this goal, the article uses textual and biographical methods, as well as a combination of comparative and cultural-historical approaches.
As a result, it was found that the poem was fully completed by 1890. The author even planned to publish it in the magazine «Zorіa». It is difficult to understand why this did not happen. Thus, some parts of her best work were lost. The writer believed that she would never write anything better, because she had put her whole soul into this poem. Lesіa Ukrainka highly appreciates «Orlove hnizdo», preferring it even to M. Starytsky's novel «Molodist Mazepy».
In fact, Olena Pchilka's poem has more echoes with the play «Hetman Doroshenko» by L. Starytska-Cherniakhivska, published in 1911. Both works are quite similar thematically, but the main differences are determined by the choice of genre: a historical play in five acts by Starytska-Cherniakhivska, a lyrical epic by Olena Pchilka. This also affected the differences in the plot.
«Orlove hnizdo» occupies a special place among Olena Pchilka's poems. The writer has six works of the specified genre. The author quickly evolves from folklore themes in «Rusalka» to higher cultural registers: reinterpreting well-known biblical stories («Iudita», «Prorok», «Debora») and describing national history («Kozachka Olena», «Orlove hnizdo»). In both historical poems, Olena Pchilka refers to the times of Petro Doroshenko's hetmanship (1665–1676). The period of Ruin was particularly interesting because of the events that took place in Ukrainian life at that time.
Conclusions. The theme successfully tested by Olena Pchilka was continued in the Ukrainian literary process of that time. It is worth mentioning here the novelist and playwright M. Starytskyi, as well as the authors of the younger generation - L. Starytska-Cherniakhivska and Lesіa Ukrainka.
«Cвітова річ» Олени Пчілки у вимірах метадраматичної парадигми
Authors: Вісич Олександра
Published: December 2024

The article analyzes Olena Pchilka’s play “The World Thing” in the light of metadrama theory. Even though traditionally metadramatic aesthetics is considered incompatible with the poetics of realism, the work of the Ukrainian author has become an example of the active use of various metadramatic elements. Methodology. The principles of metadramatic analysis are applied in the research and contribute to a deeper understanding of the Ukrainian national drama of the late 19th century, revealing the nature of the interaction between the cultural context, folklore, dramatic traditions, and reading performative techniques. The latter are important factors of theatricalization and are realized at the level of individual cues, through internal staging and are a means of synthesizing metadramatic and realistic aesthetics. The scientific novelty is that this methodology has been applied for the first time to a little-studied play by Olena Pchilka. The purpose of the article. The article aims to demonstrate the peculiarities of combining traditional and innovative elements in the work by Olena Pchilka in the context of the development of Ukrainian metadrama in the late 19th and early 20th centuries. Results. The play “The World’s Thing” depicts the birth of the idea of a theatrical production that has the potential of an inner play. The metacritical discourse is realized through the discussion about theatrical trends, acting roles (emploi), and the purpose of the theater. Anti-theatrical discussions have also a metadramatic character for they debunk everyday acting. Metadramatic poetics is based on performative elements: staging or reflection on wooing rituals, weddings, funerals, etc. Conclusions. The wedding and the trial, although not shown in the play, are phantom performances that, through constant reference to them in the characters’ remarks, contribute to the activation of cultural memory and the doubling of stage reality. The audience also acts as a metadramatic factor, whose reaction to the actions of the main characters becomes a moral and ethical catalyst.
A LEGAL STUDY ON Cr. PC 125 AND UCC
Authors: Tomar Ekta
Published: December 2024

This study aims to analyze the legal provisions related to Section 125 of the Criminal Procedure Code (CrPC) and the Uniform Civil Code (UCC) in India, focusing on their implications for women's rights and gender justice. Section 125 of the CrPC is a legal provision that enables women, children, and parents to claim maintenance from their spouses or children. The study explores the evolution of Section 125, its scope, and its impact on women’s socio-legal status in India. At the same time, it critically examines the ongoing debate around the implementation of the Uniform Civil Code (UCC), which proposes a common set of personal laws for all citizens, regardless of religion. This research assesses the intersection of these two legal frameworks and their potential role in ensuring gender equality in India.The research method involves a qualitative analysis of relevant case laws, legal provisions, and scholarly literature. The study also discusses the advantages and challenges posed by Section 125 and the UCC in the contemporary legal and socio-cultural context. This paper contributes to understanding how these two provisions can work together or independently in achieving justice and equality for women in India.
EVALUATING THE GROWTH AND INFLUENCE OF MAHATMA GANDHI UNIVERSITY’S RESEARCH: A BIBLIOMETRIC APPROACH
Authors: Nair Chithra S. , M Yasmin
Published: December 2024

PurposeThis bibliometric analysis aims to assess Mahatma Gandhi University, Kerala's research productivity, impact, and academic contributions by evaluating its publication trends, citation patterns, and global scholarly influence. The study provides a data-driven evaluation of the university's academic output from 1988 to 2025, utilizing established bibliometric indicators.MethodologyA quantitative approach is employed, sourcing data from academic databases such as the Web of Science, using the search query "Mahatma Gandhi University, Kerala." The analysis covers vital bibliometric indicators, including publication counts, citations, h-index, and journal impact factors. Advanced techniques like keyword co-occurrence analysis, co-authorship network analysis, and bibliographic coupling are applied to explore research trends, academic collaborations, and global research networks. Statistical tools like R Studio and visualization tools like VOSviewer are used for data analysis and visualization.FindingsThe study reveals a significant increase in publication volume and global citation impact starting from the early 2000s, with a peak in 2019. The most prolific authors, including Thomas S and Kalarikkal N, show extensive publication output and high citation impact. Key research areas include polymer science, nanotechnology, and biocomposites. India and the United States are the central collaborators in the international research network, while the university's focus on cutting-edge materials science research is evident in its top keywords.Originality/ValueThis analysis offers a comprehensive, data-driven evaluation of Mahatma Gandhi University's research, highlighting its contributions to global scientific discourse, academic collaborations, and emerging research areas. The findings provide valuable insights for policymakers and researchers, guiding future academic strategies.Social ImplicationsMahatma Gandhi University's research, particularly in sustainability, nanotechnology, and material sciences, contributes to environmental sustainability and green technologies. Its growing international recognition fosters cross-cultural collaboration and knowledge-sharing, benefiting local and global communities.