bluuebunny/crossref_metadata_2025 huggingface dataset:
Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for “Precision Medicine and Pharmacometabolomics Task Group”—The Metabolomics Society Initiative)
Authors: Kirwan Jennifer A , Brennan Lorraine , Broadhurst David , Fiehn Oliver , Cascante Marta , Dunn Warwick B , Schmidt Michael A , Velagapudi Vidya
Published: June 2018

BACKGROUND

The metabolome of any given biological system contains a diverse range of low molecular weight molecules (metabolites), whose abundances can be affected by the timing and method of sample collection, storage, and handling. Thus, it is necessary to consider the requirements for preanalytical processes and biobanking in metabolomics research. Poor practice can create bias and have deleterious effects on the robustness and reproducibility of acquired data.

CONTENT

This review presents both current practice and latest evidence on preanalytical processes and biobanking of samples intended for metabolomics measurement of common biofluids and tissues. It highlights areas requiring more validation and research and provides some evidence-based guidelines on best practices.

Although many researchers and biobanking personnel are familiar with the necessity of standardizing sample collection procedures at the axiomatic level (e.g., fasting status, time of day, “time to freezer,” sample volume), other less obvious factors can also negatively affect the validity of a study, such as vial size, material and batch, centrifuge speeds, storage temperature, time and conditions, and even environmental changes in the collection room. Any biobank or research study should establish and follow a well-defined and validated protocol for the collection of samples for metabolomics research. This protocol should be fully documented in any resulting study and should involve all stakeholders in its design. The use of samples that have been collected using standardized and validated protocols is a prerequisite to enable robust biological interpretation unhindered by unnecessary preanalytical factors that may complicate data analysis and interpretation.
Multifuncionalidad territorial y turismo. Implicaciones socioculturales, económicas y ambientales en destinos rurales emergentes. Un caso de estudio en Comala, Colima
Authors: Covarrubias Ramírez Rafael , Rodríguez Bautista Juan Jorge
Published: June 2018

El concepto de multifuncionalidad, vinculado a agricultura y al desarrollo territorial fue usado por primera vez hacia finales del siglo XX, como resultado de las transformaciones que se venían dando en las áreas rurales, las cuales estaban generando nuevas funciones económicas, socioculturales y ambientales, más allá de las funciones tradicionales del territorio. Diversos autores resaltan al turismo, en sus modalidades de turismo rural y/o ecoturismo, como una de esas nuevas funciones. En este trabajo se articula la multifuncionalidad con el turismo, y analiza las implicaciones territoriales que se pueden dar en las comunidades que se está introduciendo el turismo. El documento muestra una revisión de las funciones tradicionales del territorio así como de los diversos enfoques conceptuales de multifuncionalidad y la nueva ruralidad. La revisión de la literatura incluye investigaciones que abordan la relación de la multifuncionalidad con la actividad turística y enfatiza en las implicaciones derivadas del desarrollo del turismo en territorios rurales. Para los fines de este artículo, se toma el caso de la zona rural del municipio de Comala, en el estado mexicano de Colima, como caso de estudio. Los hallazgos más relevantes evidencian importantes transformaciones en el uso del suelo, en las actividades productivas tradicionales, al igual que cambios en el sistema de tenencia de la tierra –de ejidal a propiedad privada – todos ellos muy probablemente relacionados con la expansión del turismo en la zona.
¿Patrimonio Auténtico? El Carnaval de Negros y Blancos de la ciudad de Pasto, Colombia
Authors: Sansón Rosas Juan Fernando , Fusté-Forné Francesc
Published: June 2018

Este artículo aborda la autenticidad del carnaval de Negros y Blancos de la ciudad de Pasto, Colombia, desde la perspectiva y opinión de los actores sociales locales. A lo largo de este estudio se analizarán los impactos generados en la autenticidad del carnaval a partir de la institucionalización de la gestión del evento, las declaratorias como Patrimonio Cultural Inmaterial de la Nación y por la UNESCO, y la relación que tiene con el turismo como un producto cultural. Así, se identificará cuál es el concepto de autenticidad que se puede construir de este carnaval, basándose en la opinión de los artesanos y artistas.
Temáticas prosociales e impacto de una intervención educativa Flipped Classroom relacionada con la promoción de la salud mediante la creación relatos audiovisuales
Authors: Almela-Baeza Javier , Febrero-Sánchez Beatriz , Pérez-Manzano Antonio , Ramirez-Romero Pablo
Published: June 2018

La creación de propuestas educativas que incentivan los actos prosociales, relacionados con la promoción de la salud, son fundamentales para proporcionar una mejor calidad de vida a la población. En este sentido, es importante sensibilizar a los adolescentes en determinadas acciones prosociales, que les puedan ayudar además en su formación a nivel personal. El objetivo de esta intervención educativa, basada en la metodología Flipped Classroom, es que los adolescentes se formen sobre trasplante y donación de órganos mediante la creación de relatos audiovisuales sobre temáticas relacionadas con el tema, con el fin de mejorar su conocimiento. Para ello los adolescentes pudieron visualizar once entrevistas que explicaban los temas más importantes del trasplante y de la donación de órganos. Se presentaron más de 60 relatos audiovisuales. La propuesta fue bien aceptada y las temáticas trabajadas demostraron una gran asimilación de los conceptos básicos sobre trasplante y donación de órganos.
Nachhaltigkeitsstrategie auf kommunaler Ebene unter Einbeziehung von Multi-Stakeholder-Diskursen
Authors: Scherf Jessica , Becker Lutz
Published: June 2018

Kommunen stehen vor zahlreichen Herausforderungen zur Förderung einer nachhaltigenEntwicklung. Diese betreffen nicht nur Kommunal politik und Verwaltung, sondern auchdie Zivilgesellschaft. Wie kann dieser Wandel Richtung Nachhaltigkeit angestoßen und erfolgreichumgesetzt werden?
Involvement of mitophagy in cisplatin-induced cell death regulation
Authors: Abdrakhmanov Alibek , Kulikov Andrey V. , Luchkina Ekaterina A. , Zhivotovsky Boris , Gogvadze Vladimir
Published: June 2018

Mitophagy, the selective degradation of mitochondria via the autophagic pathway, is a vital mechanism of mitochondrial quality control in cells. The removal of malfunctioning or damaged mitochondria is essential for normal cellular physiology and tissue development. Stimulation of mitochondrial permeabilization and release of proapoptotic factors from the intermembrane space is an essential step in triggering the mitochondrial pathway of cell death. In this study, we analyzed the extent to which mitophagy interferes with cell death, attenuating the efficiency of cancer therapy. We show that stimulation of mitophagy suppressed cisplatin-induced apoptosis, while mitophagy inhibition stimulates apoptosis and autophagy. Suppression of mitophagy involved production of reactive oxygen species, and the fate of cell was dependent on the interplay between endoplasmic reticulum stress and autophagy.
IL-37 affects the occurrence and development of endometriosis by regulating the biological behavior of endometrial stromal cells through multiple signaling pathways
Authors: Jiang Jianfa , Yu Kenan , Jiang Zhaoying , Xue Min
Published: June 2018

Endometriosis (EMs) is a chronic inflammatory condition. Interleukin (IL)-37 is a member of the IL-1 family and an anti-inflammatory cytokine. This study aimed to evaluate the possible role of IL-37 in the EMs pathogenesis. We investigated the in vivo effect of IL-37 on EMs by injection with recombinant human IL-37 (rhIL-37) into EMs mice. Furthermore, we evaluated the in vitro effects of IL-37 on proliferation, adhesion, migration and invasiveness of endometrial stromal cells (ESCs), and explored whether Wnt/β-catenin and mitogen-activated protein kinase (MAPK) pathways were involved in this process. In cultured ESCs, IL-37 overexpression significantly suppressed both protein and mRNA expression of the inflammation-associated cytokines, including IL-1β, IL-6, IL-10 and tumor necrosis factor (TNF-α). Furthermore, IL-37 overexpression significantly inhibited ESCs proliferation, adhesion, migration, invasion and the activity of matrix metalloproteinase (MMP)-2 and MMP-9. In contrast, knockdown of IL-37 exerted the opposite effects. Importantly, the IL-37-mediated action in ESCs was through inactivation of Wnt/β-catenin, p38 MAPK, extracellular signal-related kinases MAPK and c-Jun N-terminal kinase MAPK pathways. Moreover, EMs mice treated with rhIL-37 showed the decreased endometriotic-like lesion size and lesion weight, lower expression of IL-1β, IL-6, IL-10, TNF-α, vascular endothelial growth factor (VEGF), soluble intercellular adhesion molecule-I (ICAM-I) and MMP-2/9 activity in peritoneal fluid compared with the wide type (WT) EMs mice. These findings suggest that IL-37 suppresses cell proliferation, adhesion, migration and invasion of human ESCs through multiple signaling pathways, thereby affecting the occurrence and development of EMs.
A Genetic Algorithm Approach for Group Recommender System Based on Partial Rankings
Authors: Meena Ritu , Bharadwaj Kamal K.
Published: June 2018

Many recommender systems frequently make suggestions for group consumable items to the individual users. There has been much work done in group recommender systems (GRSs) with full ranking, but partial ranking (PR) where items are partially ranked still remains a challenge. The ultimate objective of this work is to propose rank aggregation technique for effectively handling the PR problem. Additionally, in real applications, most of the studies have focused on PR without ties (PRWOT). However, the rankings may have ties where some items are placed in the same position, but where some items are partially ranked to be aggregated may not be permutations. In this work, in order to handle problem of PR in GRS for PRWOT and PR with ties (PRWT), we propose a novel approach to GRS based on genetic algorithm (GA) where for PRWOT Spearman foot rule distance and for PRWT Kendall tau distance with bucket order are used as fitness functions. Experimental results are presented that clearly demonstrate that our proposed GRS based on GA for PRWOT (GRS-GA-PRWOT) and PRWT (GRS-GA-PRWT) outperforms well-known baseline GRS techniques.
Buoyancy-Driven Rayleigh–Taylor Instability in a Vertical Channel
Authors: Aljahdaly Noufe H. , Hadji Layachi
Published: June 2018

Suppose that a vertical tube is composed of two chambers that are separated by a retractable thermally insulated thin membrane. The upper and lower chambers are filled with an incompressible fluid and maintained at temperatures

T

c

{T_{c}}

and

T

h

>

T

c

{T_{h}}>{T_{c}}

, respectively. Upon removal of the membrane, the two fluid masses form an unstably stratified Rayleigh–Taylor-type configuration with cold and heavy fluid overlying a warmer and lighter fluid and separated by an interface across which there is a discontinuity in the density. Due to the presence of an initial discontinuity between two homogeneous states, this problem is mathematically homologous to that of the shock tube problem with the thermal expansion playing the role of pressure. When the two fluid regions are brought directly into contact with each other and the transient interfacial fluctuations have subsided, we show the emergence of a stationary state of convection through a supercritical bifurcation provided a threshold value for the temperature difference is exceeded. We suggest a possible way for the experimental testing of the theoretical results put forth in this paper.
Interferon-γ Mediated Pathways And Mitogen Stimulated Proliferation During And After An Acute Infection
Authors: Knoll Miriam , Fuchs Dietmar , Weiss Guenter , Bellmann-Weiler Rosa , Kovrlija Bojana , Kurz Katharina
Published: June 2018

Background: Interferon-γ (IFN- γ) regulates the degradation of tryptophan to kynurenine via induction of indoleamine- 2,3-dioxygenase (IDO). Local tryptophan depletion and accumulation of toxic metabolites might impair the proliferative capacity of lymphocytes. The aim of this study was to assess the actual status of immune system activation of patients with bacterial infection in the acute phase and during convalescence in vivo and in vitro. Parameters of systemic immune system activation were evaluated for associations with proliferative responsiveness of immune cells, and compared with healthy controls. Methods: 24 patients with various acute bacterial infections were included in the group of acutely ill patients. Sixteen patients participated in a follow-up examination after convalescence. The control group consisted of 6 healthy people. To assess the status of immune system activation in vivo, inflammation parameters C-reactive protein and differential blood counts were determined. Neopterin concentrations were measured by enzyme-linked immunosorbent assay (ELISA). Tryptophan and kynurenine measurements were performed with high pressure liquid chromatography (HPLC). Peripheral blood mononuclear cells (PBMCs) were isolated from the patients’ blood and stimulated with concanavalin A (Con A), phytohemagglutinin (PHA) and pokeweed mitogen (PWM) in vitro proliferation rates were evaluated by ³H-thymidine incorporation and neopterin production and tryptophan degradation were determined in supernatants of mitogen stimulated PBMCs. Results: Patients with acute bacterial infections showed reduced tryptophan and elevated neopterin concentrations, which did not normalize after convalescence period. Higher plasma neopterin values and increased IDO-activity were associated with reduced proliferative responses in vitro after stimulation with PHA. Associations were observed during acute infection as well as convalescence. Conclusions: Results of this study show that increased immune system activation in vivo is associated with impaired proliferative responsiveness of immune cells in vitro in acute bacterial infections as well as during convalescence.
Le Plan de travail:
Authors: Raymond Guylaine , Barry Souleymane , Plourde Yolande
Published: June 2018

Dans ce texte nous présentons et partageons quelques réflexions en lien avec le plan de travail qui s’avère un outil efficace servant à organiser/structurer l’activité des élèves en classe. Nous montrons que qu’un certain rationnel sous-tend ce plan qui doit s’intégrer à la planification rigoureuse de l’enseignement, ce dernier lui donnant une cohérence. Nous concluons par quelques réflexions pédagogiques et didactiques sur cet organisateur réfléchi et efficace pour l’enseignement au primaire qu’est le plan de travail. Telle, l’idée de différentiation pédagogique qui traverse l’approche par le plan de travail dans laquelle les élèves font au quotidien l’apprentissage important de l’autonomie.
Premiers pas vers l’insertion socioprofessionnelle
Authors: Gagné Andréanne , Boily Pier-Charles , Coulombe Sandra
Published: June 2018

Cet article présente une initiative pédagogique de cantine scolaire mise en place dans un centre de formation générale des adultes de la Commission scolaire du Lac-Saint-Jean. Pour favoriser le développement de compétences sociales et professionnelles dans un cadre structuré et sécurisant proche du marché du travail, les élèves sont amenés à s’impliquer et à offrir un service de cantine dans leur centre de formation. Le contexte, les étapes de mise en place, les obstacles et les retombées de cette initiative y sont détaillés soulignant le potentiel pédagogique et la pertinence de cette initiative.
Malesky vs. Fforde
Authors: Gainsborough Martin
Published: June 2018

The article explores different ways of thinking about Vietnamese politics through an examination of the writing of Adam Fforde and Edmund Malesky. It argues that in order to adjudicate between different approaches to analysing Vietnamese politics, we need to come to a view about what we think politics actually is (i.e., ontology forms the basis on which we can answer questions about epistemology). This is very different from more positivist approaches to political analysis which argue that deciding between competing arguments is about weighing the data. I argue, by contrast, that adjudicating between rival positions has more to do with a series of a priori positions or beliefs that influence what we consider reliable data in the first place.
ISOLATION, IDENTIFICATION AND ANTIBIOTIC SUSCEPTIBILITY OF CURTOBACTERIUM FLACCUMFACIENS STRAIN PM_YT FROM SEA DAFFODIL (PANCRATIUM MARITIMUM L.) SHOOT CULTURES
Authors: Tumbarski Yulian , Georgiev Vasil , Nikolova Radosveta , Pavlov Atanas
Published: June 2018

After eight years of cultivation of Sea daffodil (Pancratium maritimum L.) shoot cultures at in vitro conditions, bacterial contamination on the plant tissues and medium surface appeared. The contamination was due to endophytic bacterium later isolated as a bacterial strain PM_YT. The colonial characteristics and cell morphology of the isolate were determined after cultivation on YEB-agar medium and coloring of microscopic preparations. The strain identification was implemented by biochemical methods (oxidase and catalase standard strip tests) and nucleotide sequencing of the 16S rRNA gene. The results from the morphological and cultural identification showed that the isolate was Gram-positive bacterium presented from small, short rods, forming small (size of 1-3 mm), round-shaped, yellow- to slightly orange-colored colonies. The results from biochemical identification showed that the strain was oxidase-negative and catalase-positive. The comparative 16S rRNA gene sequence-based phylogenetic analysis revealed 99% pairwise similarity of the strain PM_YT to the bacterial species Curtobacterium flaccumfaciens. Antibiotic susceptibility was implemented by Bauer-Kirby disc diffusion method and the results demonstrated that the isolate was most sensitive to the antibiotics belonging to inhibitors of protein synthesis group, especially to tetracycline, doxycycline, amikacin, rifampin, lincomycin, chloramphenicol, erythromycin, streptomycin and ciprofloxacin.
Selection Bias and Outcomes for Preterm Neonates
Authors: Atwell Kerryn , Callander Emily , Lindsay Daniel , Marshall Peter Blake , Morris Scott Adam
Published: June 2018

BACKGROUND:

Reported survival and neurodevelopmental outcomes at 23 weeks’ gestation are based on the infants admitted to NICUs. In this study, we aim to describe the association between clinical characteristics and admission to NICU at 23, 24 and 25 weeks’ gestation.

METHODS:

Cohort data from 2 national databases enabled comparison of the clinical characteristics all Australian births and all NICU admissions during 2010–2013 at 23, 24, and 25 weeks’ gestation.

RESULTS:

NICU admission occurred in 15% of all births at 23 weeks, in comparison with 49% at 24 weeks and 64% at 25 weeks. At 23 weeks, live-born infants were less likely to be admitted to NICU with birth weight <500 g compared with >500 g (13% vs 43%, P < .0001), and boys were admitted less compared with girls (33% vs 43%, P < .018). In contrast, birth weight (including birth weight <500 g) and sex had little or no impact on NICU admission at 24 and 25 weeks. Only 8% of live births were born by caesarean delivery at 23 weeks compared with 33% at 24 weeks and 48% at 25 weeks’ gestation.

CONCLUSIONS:

In the Australian population, admission to the NICU is more likely to be influenced by birth weight and sex at 23 weeks’ gestation when compared with 24 and 25 weeks’ gestation. Survival outcomes at 23 weeks may be affected by less active perinatal care. Uncertainty exists regarding the generalizability of current data regarding survival and developmental potential of live-born 23-week infants.
Cyperaceae in Mexico: Diversity and distribution
Authors: González-Elizondo M. Socorro , Reznicek Anton A. , Tena-Flores Jorge A.
Published: June 2018

Background: Cyperaceae, with about 5,500 species and 90 genera worldwide, are the third largest family among Monocots. A unique combination of morphological and karyotypical features, among which stand holokinetic chromosomes, favors a rapid evolution and diversification and a high level of endemism in some groups. Preliminary checklists of Mexican sedges have been published but an updating of the taxonomy and nomenclature of the group for the country is required.Questions: How many and which species and genera of Cyperaceae are in Mexico?, what patterns of geographic distribution display those species?, which are the main gaps in the systematic knowledge in the family?Study site and years of study: Mexico, 1990 to 2016.Methods: A database of Mexican Cyperaceae was generated with basis in literature review, study of herbarium specimens (11 herbaria in Mexico and the United States) and field work, the last mainly focused on Carex . Diversity and endemism level were calculated. Besides, we analyzed in different space scales their distributional range.Results: Our dataset includes 460 species and 20 infraspecific taxa in 21 genera that belong to 10 of the 17 tribes of the family. Subfamily Cyperoideae includes almost 100 % of the Mexican sedges, as only one representative of subfamily Mapanioideae is known for the country. At the generic level, a drastic reduction in number (21) in comparison to previous inventories (27) results of recent phylogenetic and taxonomic rearrangements. The most diverse genera are Carex (138 taxa) and Cyperus (125), followed by Rhynchospora (65) and Eleocharis (57). Sedges in Mexico are found from sea level to above 4,300 m, in all types of vegetation. The highest diversity was found for Chiapas (237 taxa, 52 % of the total) and Veracruz (206 taxa, 45 %), followed by Oaxaca and Jalisco. Two genera ( Cypringlea and Karinia ) and 111 species or infraspecific taxa are endemic to Mexico (24 %), 43 of them micro-endemic (only known from one state in the country). Endemism increases to 57 % when the biogeographic extension known as Megamexico is included. Forty six names are excluded from the Mexican flora.Conclusions: Regardless of the addition of taxa and refining of the databases, the checklist presented here is still preliminary. Collection deficiencies and insufficient taxonomic revision for Mexican sedges are reflected in gaps in their knowledge. There are at least 45 undescribed species; including them the richness of Mexican sedges would exceed 500 species. Many complexes of species are in need of taxonomic revision, mainly in Carex but also in Bulbostylis , Cyperus , Eleocharis , Rhynchospora and Scleria . To advance in the inventory and better understanding of the diversity of Mexican Cyperaceae, we propose some research topics to be addressed in the short term.
Sur l'Entropie Contrôlée des Systèmes: Transformations de la Matière Condensée (On the Controlled Entropy of the Systems: Condensed Matter Transformations)
Authors: Serpa Nilo
Published: June 2018

Cette thèse traite de la mise en ouvre d'un nouveau mode de gestion des déchets urbains en termes de la destination non-agressif et productif des débris, à de faibles coûts énergétiques et à forte réutilisation des sous-produits. Il repose sur les fondements scientifiques établies par la thermodynamique, la théorie classique du champ et par les disciplines empiriques qui traitent de propriétés des éléments chimiques et des technologies de capture calorifique à partir de sources éloignées. Visant à la transformation de toute forme de matière condensée, ce travail est principalement intéressés par les déchets dits infectieux, parce qu'ils ont dune plus grande virulence, l'infectiosité et concentration, et les déchets de type <>, qui sont des objets et instruments contenant des coins, des arêtes ou des protubérances rigides et aiguës capables de coupe ou de forage. Néanmoins, le modèle s'applique également à tous les types de déchets, à l'exception des déchets radioactifs pour des raisons évidentes de sécurité. Cet essai propose un système industriel de recyclage des déchets basé sur la pyrolyse induite par plasma et guidé par la théorie proposée des champs caloriques sous entropie contrôlée.

Mots-clés: déchets nosocomiales, thermodynamique, champ calorique, plasma, pyrolyse, énergie solaire, durabilité

====================================================================================================== 

This thesis discusses the implementation of a new way of urban waste management in terms of its non-aggressive and productive destination, at low energy costs and with high reuse of byproducts. It is based on scientific foundations established by thermodynamics, classical field theory and empirical disciplines that deal with properties of chemical elements and with technologies of calorific capture from remote sources. Aiming at the transformation of any form of condensed matter, it is primarily interested in the so-called infectious waste, because they have greater virulence, infectivity and concentration, and wastes of type <>, which are objects and instruments containing corners, edges or rigid and acute protuberances capable of cutting or drilling. Nevertheless, the model also applies to all types of waste, with the exception of radioactive waste for obvious safety reasons. Present work proposes an industrial system to recycling waste based on pyrolysis induced by plasma and guided by the proposed theory of caloric fields under controlled entropy.

Key words: nosocomial waste, thermodynamics, caloric field, plasma, pyrolysis, solar energy, sustainability
Narrative as a psychotechnical tool in working with personality sovereignty of the adolescent
Authors: Elfimova M.M.
Published: June 2018

We consider the issues of the adolescent’s personal sovereignty formation in a narrative training. The narrative is defined as a text, a meaning system, first divided between people and then interiorized. We substantiate the possibility of using the narrative as a psychotechnical tool in working with the personality sovereignty of the adolescent. Its formation is connected to the adolescent’s mastering of reflexive action aimed at the meaningful organization of his/her experience of successful autonomous behavior. The essence of the narrative training is constructing the narrative (narrative metaphor). We consider two aspects of the narrative metaphor: the domain of action landscape and the domain of meaning, that help the adolescent to signify and make sense of the unique episodes of his/her life and to structure the fragmented experiences of his/her successful independent behavior.
This Is Who We Are: Promoting Professional Behaviors and Civility in Nursing Education
Authors: Williamson Myrna
Published: June 2018

Background: Incivility, lack of professionalism, distrust and uncaring behaviors negatively impact the teaching and learning environment. Nurse educators concluded that many of these disturbing trends could be prevented and/or managed effectively if faculty and students were educated about expected professional behaviors.Aim: To promote a healthy academic community through the engagement in activities focused on professional behaviors among nursing faculty and students.Methods: Professional development activities were planned to promote a healthy academic community by educating faculty and student participants regarding professional behaviors in the teaching and learning environment. Faculty and student initiatives were designed to promote wellness, professionalism, civility, caring, and trust. The initial activities were entitled, “This Is Who We Are.”Results: Initial outcomes included a position statement created and signed by faculty to facilitate professional behaviors. Students created and signed a position statement exemplifying the desired behaviors of the cohort.Conclusions: Engagement activities are ongoing involving all faculty and all nursing student cohorts during their first semester in nursing school with additional training and updates planned. Initial anecdotal evidence from faculty and students regarding the benefits of these offerings are strongly supportive and demonstrate the beginning steps to a healthy academic environment in nursing education.
A Pilot Study: Promoting Understanding and Peer Success (PUPS) in the Campus Community
Authors: Walker Laura Pruitt , Helms Kimberly D.
Published: June 2018

Background: Suicide is one of the leading causes of death in the United States and is escalating in some populations, such as college students. Suicide is the 2nd leading cause of death among college students (Caruso, 2018). The number one cause of suicide is depression (Caruso, 2018).Aim: The aim of the Promoting Understanding and Peer Success (PUPS) project is to explore innovative approaches to teaching and learning in a psychiatric mental health course and to provide early identification and intervention for students or staff who are identified as “at risk” for suicide, depression, anxiety, and substance abuse.Methods: Researchers are utilizing a qualitative approach when collecting data from nursing students involved in this study. The Nursing Students are asked to engage in focus group interview questions and to complete a self-reflection activity focused on the PUPS project.Results: Nursing students have conducted suicide, depression, anxiety and substance abuse screenings on approximately 500 campus student and staff participants thus far. Many of these screenings have resulted in distribution of educational resources, referral and follow up with counseling services.Conclusions: Researchers are continuing to collect data in the form of focused group interview questions, anecdotal comments, and end of the term course evaluations from the nursing students. Thematic coding is pending. Based upon anecdotal comments from the nursing students, the course faculty/researchers of this study believe the PUPS Project is successful.
Editors Note
Authors: Kazer Meredith
Published: June 2018

No abstract available.
Magic Mike, Dirty Dancing, and the (Empty) Promise of Heteromasculinity
Authors: Tsai Addie
Published: June 2018

In 1987, Eddie Murphy performed a comic sketch about white men dancing that would inform future movers and makers of white male dancing in American popular culture, helping to create a trope mocking white men for their inability to dance, most often referred to as the “white man dance.” At that time, Saturday Night Live, with the help of its host Patrick Swayze, fresh off the popularity of his work in sleeper hit Dirty Dancing, contributed to the trope itself with a sketch comparing the hypermuscular physique of Swayze vs. the flabby physique of comedian Chris Farley. Almost thirty years later, American popular culture would see a return to a renewed interest in the dance film with the stripper film Magic Mike. This article argues that although Magic Mike, like Dirty Dancing, relies on the makeover trope as its narrative and thematic engine, Magic Mike revises the popular dance film format to instead focus on the relationship between two men, Mike and Adam, rather than on a heterosexual partnering. Magic Mike’s focus on this male-to-male relationship inevitably comments on the exchange between heteronormative masculinity and compulsory heterosexuality and their assumed whiteness.
Scratching the surface of spectacle: Black hypermasculinity and the Television Talent Show
Authors: Robinson Laura Helen Carol
Published: June 2018

This study explores the construction of black hypermasculinity in television talent show competitions through the re-valuing of spectacle as an aesthetic experience. Drawing on a screendance analysis of eighteen duet, trio and group performances featured in ITV’s Britain’s Got Talent (BGT) and Sky1’s Got To Dance (GTD) between 2008-2013, this study explores the circulation of black hypermasculinity and the potentiality for an alternate reading of spectacular displays of athleticism. Building upon Kristen Whissel’s concept of the emblematic nature of the special effect in cinema, the re-valuing of televised spectacles reveals themes regarding the black male experience in these competitions. Rather than dismissing these performances as commercial spectacles that recirculate notions of black hypermasculinity, these corporeal and televisual special effects instead highlight the thematic narrative of the reality television journey through themes of aspiration and transformation. Crews constructs images of superheroes, cartoons, animals and cyborgs, manipulated by camera angles and editing, that operate as both light entertainment and a reflection of the young black male experience in mediascope of reality television. The creation of spectacular and glossy images on screen therefore reveals the potentiality of a fluid gender and racialized representation.
"Fresher Than You": Commercial Use of YouTube-Native Dance and Videographic Techniques
Authors: Harlig Alexandra
Published: June 2018

This article focuses on four examples of commercial use of web-native and amateur video and dance aesthetics, including music videos and videos promoting clothing brands, and how corporate logics have adopted these genres and caused them to adapt in turn. Commercial use both subsumes and broadcasts the innovations of dance communities, amateur filmmakers, and subcultural entrepreneurs. At the same time, I argue that the possibility of greater self-control for the making and distributing of filmed popular dance in the social media context renders commercial mediation of popular dance more desirable to many communities of practice. Through looking at generic and technical attributes of the examples, I address the continued rhetorical power of binaries like amateur and professional, commercial and participatory, categories the reality of dance in social media in fact undermine. The commercial use of web-native videographic and dance styles is complicated by new opportunities for representation, remuneration, and creative control that come with the new platforms and modes of production. These music videos and advertisements transmit social media-native movement, videographic, and promotional techniques, but still do so within longstanding infrastructures that primarily benefit those with preexisting economic and cultural capital, and along lines of class and race.
DESIGNING BATCH-MANUFACTURING ENTERPRISES USING ONTOLOGIES
Authors:   Belarusian State University of Informatics and Radioelectronics, Golenkov V. , Taberko V. ,   JSC «Savushkin product», Ivanyuk D. ,   JSC «Savushkin product», Rusetski K. ,   Belarusian State University of Informatics and Radioelectronics, Shunkevich D. ,   Belarusian State University of Informatics and Radioelectronics, Davydenko I. ,   Belarusian State University of Informatics and Radioelectronics, Zakharov V. ,   Belarusian State University of Informatics and Radioelectronics, Ivashenko V. ,   Belarusian State University of Informatics and Radioelectronics, Koronchik D. ,   Belarusian State University of Informatics and Radioelectronics
Published: June 2018

This article presents an ontological approach to designing batch manufacturing enterprises based on formal ontologies. Belarusian enterprise JSC «Savushkin product» is used as an example. In particular, this article covers formalization of standards that form the basis for enterprise operation, with ISA-88 used as an example. We propose to treat the ISA-88 standard as an ontology of a batch manufacturing subject domain, represented in the form of the natural language text. Formalization of a standard then boils down to mapping structure and contents of the standard to a hierarchy of subject domains and respective ontologies. Formal representation of a standard forms the basis for corporate intelligent system and simplifies automation of a wide range of tasks, such as providing informational service for employees, making enterprise adherent to standards and formal standard adherence evaluation. Fundamental new result presented in this article is comprised of using formal representation of the industry standard, implemented using graphodynamical model of knowledge representation and processing as a basis for creating an enterprise-wide intelligent system.
INFORMATION MODEL OF SCHOLARLY PRODUCTS
Authors:   Saint Petersburg State University, Begler A.
Published: June 2018

Results of the scientific research – scholarly products – are not homogenous. They appear in different forms during different research activities and might be described with several related concepts. First one is the research workflow, which consists of several phases: from searching of the relevant information through data collecting to dissemination of the results. Every phase characterized by the activities, which described by scholarly primitives and the research products are the results of this activities. Second, the research products itself are represented by information of different types: content, data and knowledge. For example, during searching of the relevant information scientist produce several types of information: collection of papers/datasets/etc, several facts, derived from them, and research hypothesis, which express researcher’s personal ideas. For producing them modern scientists use research tools (the third concept), which could be distinguished by the information type too, but not always one-by-one: for example, most of the reference management programs are not only storing the papers, but also maintaining the work on the text reading. One more related concept – information availability, reflects openness and discoverability of the scholarly products and might be to the different degree supported by the instruments. We put these four concepts into the information model of the scholarly products, which will be helpful for managing research results.
ONTOLOGICAL MODEL FOR INTEGRATION OF STRUCTURALLY HETEROGENEOUS SPATIAL DATABASES OF VARIOUS SUBJECT AREAS INTO A UNIFORM REGIONAL DATABASE
Authors:   Ufa State Aviation Technical University, Pavlov S. , Efremova O. ,   Ufa State Aviation Technical University
Published: June 2018

Article is devoted to a solution of the problem of integration of spatial databases into the uniform regional database for the organization of information support of decision-making for management of a large industrial region. The authors propose an ontological model for semantic-level integration that would allow description of structure of heterogeneous spatial databases within a single methodological framework highlighting in their composition the ontologies of spatial, attributive and metadata, and thereby ensuring the possibility of their further integration into a single regional database. Within the framework of the proposed ontological model, an algorithm for constructing and integrating ontologies into the software for integrating spatial and spatial databases that are heterogeneous in structure and subject has been developed. Approbation of the developed algorithm is carried out on the example of creating a single regional database of spatial data in the Geoinformation System of the Republic of Bashkortostan’s administration.
ON THE QUALITY OF ONTOLOGICAL MODELS
Authors:   St. Petersburg Institute for Informatics and Automation of the Russian Academy of Sciences, Mikoni S.
Published: June 2018

Factors affecting the quality of ontological models are discussed. General requirements to their quality are formulated. The dependence of the quality of the model on the quality of the definitions of the concepts entering into it is indicated. The role of the cognizing subject in the Frege triangle is formalized. The proximity of the meaning of the word to the image is created by the synergetic effect of a correct understanding of the concept. Hence follows the importance of the primary use of the words of the national language to denote concepts. Examples of false-oriented terms are given. The ontological model of the quality of systems with control is analyzed. As the main drawback of the model, the incompatibility of narrowly disciplined definitions of concepts in an interdisciplinary model was noted. Definitions of generalizing concepts are proposed. On their basis, a scale of active stability of systems with control has been developed.
EVERGETICS AS A METHODOLOGICAL BASIS FOR MANAGING OF DEFECTS IDENTIFICATION AT THE PRE-DESIGN STAGE OF DATA PROCESSING SYSTEMS
Authors:   Ufa State Aviation Technical University, Gvozdev V. , Chernyakhovskaya L. ,   Ufa State Aviation Technical University, Blinova D. ,   Ufa State Aviation Technical University
Published: June 2018

Data processing systems are considered not only as components of the information structure, but also as an integral component of modern society. This allows to coordinate approaches for defect management of data processing systems with approaches used in managing social systems. The main attention is paid to the defects of the data processing systems that arise at the pre-project stage, caused by lack of uniform understanding of the problem situation by the actors, involved in resolving the problem situation. On the basis of the provisions of evergetics and the theory of intersubjective management a class of defects is allocated, arising due to violation of co-evolution between the states of external to the data processing systems environment and the properties of the system. The structuration of the process, corresponding to a pre-design stage was carried out, result of which is the specification of user’s requirements of data processing systems. Key factors of defects occurrence are allocated. The novelty of the approaches described in the paper is in considering from the positions of the evergetics the role of specification of user requirements as a "bridge" between the "life world" and the "world of systems".
FORMALIZATION OF THE COGNITIVE PROCESS USING THE BASIS OF MODELS
Authors:   St. Petersburg Institute for Informatics and Automation of the Russian Academy of Sciences, Mikoni S.
Published: June 2018

All human mental activity is a modeling of its external and internal world and is based on the application of models. The cognitive and сonstructive activity of man can't be imagined through the immense variety of particular models the uses. The paper proposes the structural, functional and operational components inherent in different degrees of any solvable model. The universality of the components is explained by their belonging to the model of the predicate language of the first order, which is the basis of any mathematical models. These basic properties of the model are used to describe the model of knowledge acquired by a person in the process of understanding the surrounding and internal environment. The cognitive process itself is also carried out with the use of models called models of instrumental knowledge. As a basic model of the cognitive process, the "pyramid of cognition" of Ackoff is adopted. The concepts used in it are defined. Each stage of the formation of a model of new knowledge and the instrumental knowledge used to acquire it is described using basic models, which allows us to represent the cognitive process in terms of modeling.
Characterization of an Orthotopic Rat Model of Glioblastoma Using Multiparametric Magnetic Resonance Imaging and Bioluminescence Imaging
Authors: Le Trung N.T. , Lim Heeseung , Hamilton Amanda M. , Parkins Katie M. , Chen Yuanxin , Scholl Timothy J. , Ronald John A.
Published: June 2018

Glioblastoma multiforme (GBM) is the most common primary brain tumor, with most patients dying within 15–18 months of diagnosis despite aggressive therapy. Preclinical GBM models are valuable for exploring GBM progression and for evaluating new therapeutics or imaging approaches. The rat C6 glioma model shares similarities with human GBM, and application of noninvasive imaging enables better study of disease progression. Here, multiparametric magnetic resonance imaging (mpMRI) and bioluminescence imaging (BLI) were applied to characterize longitudinal development of orthotopic luciferase-expressing C6 tumors. Across all rats (n = 11), a large variability was seen for BLI signal, a relative measure of C6 cell viability, but in most individuals, BLI signal peaked at day 11 and decreased thereafter. T2 and contrast-enhanced T1 tumor volumes significantly increased over time (P < .05), and volume measures did not correlate with BLI signal. After day 11, tumor regions of noncontrast enhancement appeared in postcontrast T1-weighted magnetic resonance imaging, and had significantly higher apparent diffusion coefficient values compared with contrast-enhanced regions (P < .05). This suggests formation of ill-perfused, necrotic regions beyond day 11, which were apparent at end-point–matched tissue sections. Our study represents the first combined use of BLI and mpMRI to characterize the progression of disease in the orthotopic C6 rat model, and it highlights the variability in tumor growth, the complementary information from BLI and mpMRI, and the value of multimodality imaging to better characterize tumor development. Future application of these imaging tools will be useful for evaluation of treatment response, and should be pertinent for other preclinical models.
Validação Experimental de uma Microrrede com Controle Centralizado e Despachável
Authors: Brandao Danilo I. , Pomilio José A. , Marafão Fernando P. , Alonso Augusto M. S.
Published: June 2018

Baseado em uma arquitetura centralizada e despachável, este trabalho demonstra que é possível operar uma microrrede sob condições de ilhamento ou interconexão, de forma resiliente e confiável, sem que seja necessário conhecimento prévio de características da rede ou técnicas de sincronização. A implementação da microrrede baseia-se em uma metodologia de controle ordenador/subordinado (mestre/escravo), na qual a coordenação de agentes (i.e., geradores distribuídos) é determinada pelo algoritmo power-based control, apenas requerendo um canal de comunicação de baixa taxa de transmissão. Por meio de um protótipo experimental, comprova-se a viabilidade da proposta na operação do sistema, com uniforme contribuição de potência entre seus agentes distribuídos, durante interconexão, ilhamento intencional,ilhamento não intencional, falha de comunicação e transições entre modos de operação.
Protected geographical indication recognition and willingness to pay: A case of grojec apple
Authors: Ahrendsen Bruce L. , Majewski Edward
Published: June 2018

The Grojec region of Poland is an important region for apple production and accounts for 40 percent of domestic apple production. Apple growers from the region made an attempt to strengthen their competitive position through registering their apples as Protected Geographical Indication (PGI) products. The European Commission’s PGI allows food producers to obtain market recognition and a premium price for their products. Although the Grojec Apple received PGI registration in 2011, little has been done to promote apples with the PGI label. Two important research questions are addressed: 1) Does the Polish market recognize Grojec Apple PGI, and 2) Does the market value Grojec Apple PGI? Logit and regression models are estimated using survey data collected during an International MBA in Agribusiness and Commerce study week in Warsaw. Only 22% of consumers recognize Grojec Apple PGI. Yet, 70% of consumers indicate they are willing to pay more for the product and their average willingness to pay (WTP) premium is 32%. Results indicate use of the PGI label may be effective in improving sales and profit margins for Grojec Apple producers and their affiliated cooperatives. Older consumers are more likely to indicate a WTP premium. Males, smaller households, and consumers less sensitive to apple price indicate a higher WTP premium. An advertising campaign promoting Grojec Apple PGI as a better product may be effective at increasing consumer likelihood to pay more and WTP premium. Although “Grojec” is already familiar to most consumers in central Poland as a region for apples, a Grojec Apple with PGI label would assure consumers they are purchasing apples from the Grojec region and the apples are high quality.

JEL Code: D12, Q13, Q18