bluuebunny/crossref_metadata_2025 huggingface dataset:
Barriers to mental health help-seeking among young-adult medical students in Egypt: a cross-sectional study
Authors: Elsaeidy Ahmed Saad , Rabie Salma , Adwi Mohamed , Abdel-Haleem Muhammad Amer , Shalaby Mahmoud Mohamed Mohamed , Bahnasy Ayman Ashraf Elsayed , Sameh Mostafa , Shaker Raneyah H. M. , Elsaeidy Khaled Saad
Published: January 2023

Purpose
High levels of mental distress were reported among medical students, however, only a small portion decides to seek help. This study aims at identifying the most diagnosed mental disorders among medical students in Egypt, recognizing their family attitudes and the major barriers that deter them from help seeking.
Method
This is a cross-sectional study conducted on Egyptian medical students from different universities. Each student filled out a questionnaire assessing the sociodemographic factors, the presence of previously diagnosed mental disorder, the barriers to mental health help-seeking using 27 items from the 30-item Barriers to Access to Care Evaluation (BACE), and the family's attitude towards mental health.
Result
1037 students filled completed the questionnaire, and 23.4% mentioned being previously diagnosed with mental illness. The top three major barriers were attitudinal, reflecting a tendency for self-reliance, and a low preferability for emotional expressiveness. The fourth major barrier was stigma-related, representing a fear of what the family might say or think. Most of the students’ families had a positive attitude and support for mental health. The parent’s mental health attitude was positively associated with higher levels of education.
Conclusion
Multiple attitudinal barriers represented hindrance to mental health help-seeking and reflected self-reliance tendency among the study participants. This self-reliance proclivity needs to be investigated since it is a common theme noticed among the young generations, however, it could be used for designing self-help programs that strengthen mental health integrity and literacy.
A Novel Nearest Neighbors Algorithm Based on Power Muirhead Mean
Authors: Shahnazari Kourosh , Ayyoubzadeh Seyed Moein
Published: January 2023

K-Nearest Neighbors algorithm is one of the most used classifiers in terms of simplicity and performance. Although, when a dataset has many outliers or when it is small or unbalanced, KNN doesn't work well. This paper aims to propose a novel classifier, based on K-Nearest Neighbors which calculates the local means of every class using the Power Muirhead Mean operator to overcome alluded issues. We called our new algorithm Power Muirhead Mean K-Nearest Neighbors (PMM-KNN). Eventually, we used five well-known datasets to assess PMM-KNN performance. The research results demonstrate that the PMM-KNN has outperformed three state-of-the-art classification methods in all experiments.
Demographic Diversity of Genetic Databases Used in Alzheimer’s Disease Research
Authors: Field Robert I. , Orlando Anthony W. , Rosoff Arnold J.
Published: January 2023

For several years, experts have warned about the lack of diversity in genetic research databases, and researchers have devoted time and resources to recruiting subjects from underrepresented subgroups. In this study, we review published reports in academic journals of genetic studies of Alzheimer’s disease to note whether demographic diversity was indicated in the reports and, if so, the extent of representation of non-European subjects over the period from 1997 to 2022. We use multivariate regression analysis to analyze changes over time and to explain variation across studies. Our analysis indicates that reported diversity has not changed over time. Rather, it appears to have remained relatively constant since GWAS (Genome-Wide Association Studies) were first used in the 1990s. We find most variation to be across journals rather than within journals, suggesting that characteristics of journals are an important influence on the dissemination of research with diverse samples. Lack of racial diversity in genetic databases used to develop clinical applications could lead to disparities in the effectiveness of those applications for underrepresented groups.
Development and Validation a nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma
Authors: ouyang haiping , Wang Jinkui , Wang Zhongliang
Published: January 2023

Background
Most malignant bone tumors in children and adolescents are osteosarcomas. Pediatric osteosarcoma has a high mortality rate due to pulmonary metastasis, which occurs in a short period of time. We would like to establish a nomogram to predict the risk of pulmonary metastasis of pediatric osteosarcoma to help doctors conduct early intervention and and improve their survival rate.
Methods
The clinicopathological information of patients was downloaded from SEER to identify pediatric osteosarcoma from 2004 to 2018. We analyzed the independent risk factors for pulmonary metastasis of pediatric osteosarcoma in the training cohort using univariate and multivariate logistic regression. Using these risk factors, we established a Nomogram prediction for pulmonary metastasis of pediatric osteosarcoma. We used three indicators to evaluate the accuracy of the nomogram. These three were calibration curve, c-index and area under the receiver operating curve (AUC). The clinical value of this nomogram was evaluated using Decision curve analysis (DCA).
Results
A sum of 1362 pediatric patients with osteosarcoma were involved in this research. They were randomly divided into the training cohort (N = 965) and the validation cohort (N = 397). In training cohort, univariate and multivariate logistic regression analysis showed that there were four independent risk factors, namely T stage, N stage, surgery, and radiotherapy. We constructed a new Nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma. In the training cohorts and validation cohorts, the C-index was 0.699 (95% CI, 0.656–0.741) and 0.736 (95% CI, 0.675–0.797),respectively, indicating that the nomogram had good accuracy. The AUC of training group and validation group showed good predictive ability.
Conclusion
This study constructed a new nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma. Our nomogram can help doctors provide accurate assessment of individual risk, active monitoring and follow-up of patients, and prevent pulmonary metastasis in pediatric osteosarcoma.
Microfacial Analyses on the Building Stones of the Maya Site of Calakmul
Authors: García-Solís Claudia Araceli , Quintana-Owen Patricia , López-Doncel Rubén Alfonso , Illescas-Salinas Juan Francisco
Published: January 2023

This article focuses on the petrographic and microfacial characterization of the building stones, buildings, monuments, and quarries of the archeological site of Calakmul to document aspects of composition, lithologies, and stone exploitation. Microfacial analysis shows that the used building rocks are highly recrystallized biosparudites (grainstones to packstones) with the presence of reef and shallow waters fauna (boundstones). These rocks have an intermediate porosity (10–20% pore volume values) and XRD analysis confirms that the mineral composition is mainly calcite, but also dolomite. Microfacies analysis demonstrate that limestone of the stelae and the SubIIc-1 main façade come from the same quarry and have fine texture corroborate that these stones are suitable materials for carving and lime production. Samples from St. XX Gran Acropolis and from Chan Chi’ich Group come from a different quarry. These results help us to know the origin of the rocks, their use in the different buildings and monuments studied, and to contribute to the knowledge of their lithological characteristics and their response to weathering and thus provide important information that will help in taking decisions in case of probable measures of restoration and conservation of the rocks in the Calakmul region.
New Theorems on Theta-function Analogues and Explicit Evaluations of Ramanujan's Remarkable Product
Authors: Kumar S Vasanth
Published: January 2023

The authors have requested that this preprint be removed from Research Square.
Frailty among Community Dwelling Older Adults: Prevalence and Associated Factors
Authors: Ali Sageda Magdy , AbdElhameed Soad Hassan , Mohamed Doaa
Published: January 2023

Background: Frailty is an important and a highly prevalent health problem in older adults that has a negative impact on health related outcomes. The importance of studying frailty comes from the fact that its merely associated with aging but not an inevitable process.
Aim: To assess prevalence of frailty and its associated factors among community-dwelling older adults.
Method: A community based cross sectional study was used withcluster sampling technique targeted 300 older adults in six urban and rural regions affiliated to Dakahlia governorate. Data was collected using, Mini-mental State Examination, demographic and health-related data structured interview questionnaire, Katz and Akpom scale, Lawton and Brody scale, the Mini Nutritional Asses sment questionnaire and Frailty was measured using survey of health, and aging, and retirement in Europe of the frailty indicator.
Results: Prevalence of frailty was 64.7% among the studied older adults, and only 5.3% were non frail. Age, current work, comorbidity, polypharmavy, IADL, and malnutrition were significant independent predictors for frailty (β 0.136, -0.148, 0.117, 0.118, -0.209, and 0.401 respectively), p < 0.05 for all, and responsible for 72.4% of frailty (R2 = .724).
Conclusion: It can be concluded that frailty was highly prevalent in community-dwellers in Egypt urban and rural regions. Risk factors of frailty include female gender, widohood, illiteracy, living arrangements, previous hospitalization, drug compliance, periodic checkup, engagement into social practices, and smoking. Moreover Older adults' age, work status, income, comorbidities, polypharmacy, functional status, and nutritional status were found as the main factors associated with frailty.
Recommendations: Assessment of associated risk factors of frailty in older adults should be done through community-based healthcare programs for early diagnosis and management.
An Unexpected Settler in the Right Ventricular Outflow Tract in Pulmonary artery sarcoma
Authors: Ahmad Akhlaq
Published: January 2023

Pulmonary artery sarcoma (PAS) is a sporadic malignant tumor that mainly originates from the pulmonary arteries. However, PAS may also involve the right ventricular outflow tract, which may lead to obstruction, syncope, or sudden death. Early diagnosis is essential to prolonging survival and improving the quality of life. Herein, we report a case of a young female patient admitted for pulmonary malignancy and acute pulmonary embolism. The patient had a mass in her right ventricular outflow tract, which was detected by transthoracic echocardiography. Computed tomography and magnetic resonance imaging revealed the invasion depth and extent of the lesions. Surgical resection improved hemodynamics, and pathological and immunohistochemical tests confirmed the diagnosis of a pulmonary artery sarcoma. Local recurrence was detected in the adjacent tissues several months after the surgery. Given the potential risk of reoperation, the patient was suggested to undergo conservative treatment.
MFRRI:Research on multi-feature joint recommendation algorithm based on graph neural network
Authors: Simon Bastien , Joliat Daniel , Weber Erik , Rayment Andrea
Published: January 2023

With the rapid development of Internet technology and the comprehensive popularity of Internet applications, online activities have gradually become an indispensable part of people's daily life. Internet activities are becoming an indispensable part of people's daily life. How to help users quickly find valuable information from the huge amount of data has become a great challenge for the Internet industry. The traditional recommendation system based on collaborative filtering can take advantage of big data because it can well find users with the most similar interests and recommend the items they are interested in, showing a good recommendation effect and has been the main direction of recommendation algorithm research. In recommender systems, most of the information has a graph structure, and the graph neural network GNN technique can capture the relevance of graphs through message passing between graph nodes, so GNNs are often used to generate embedded representations of users/items. However, traditional GNN-based recommendation algorithms are only able to handle regular topological graphs composed of a single type of node, while the data in the current network is not composed of only a single type of node. the main content of this paper is the GNN-based knowledge graph recommendation model. The model can effectively capture the potential interest of users through the user relationship graph for the recommendation. A joint multi-feature representation method is proposed. For user-item interaction, the representation of node features in the case of sparse network connectivity is enhanced by using multi-order topological structure information in information networks. The model in this paper was verified to perform significantly better than the baseline approach by conducting experiments on public datasets.
Effect of pre-existing crystals and melt homogeneity on the decompression-induced crystallization of hydrous rhyodacite magma
Authors: Matsumoto Kazuhisa , Okumura Satoshi , Tomiya Akihiko
Published: January 2023

Decompression-induced crystallization is an important process that controls the behavior of volcanic eruptions because it strongly affects magma rheology and degassing behavior in the shallow parts of volcanic conduits. Several decompression experiments have been performed to understand and model the crystallization processes; however, the effect of superheating (i.e., heating above the liquidus temperature for a definite period of time) before decompression has not been elucidated, despite the proposal of its importance in previous cooling experiments. As the superheating influences the number of pre-existing crystals and melt homogeneity, it is expected to control decompression-induced crystallization. In this study, we investigated the effects of pre-existing crystals and melt homogeneity on crystallization during the decompression of rhyodacitic magma at a temperature of 900 °C. The magma studied herein has a liquidus temperature of ~920 °C. Five starting materials were prepared via heating at different super-liquidus temperatures (940, 970, 1050, and 1300 °C) and a sub-liquidus temperature (900 °C) using an internally heated pressure vessel and a cold-seal pressure vessel, respectively. Decompression experiments using these starting materials were conducted from 130 to 30 MPa at decompression rates of 5, 20, and 100 MPa h–1. When the melt was completely homogenized (at 1050 and 1300 °C), no crystals were formed at 100 MPa h–1 and the small amounts of crystals heterogeneously formed along the capsule wall were found at 5 and 20 MPa h–1. At the same decompression rate, the number density of plagioclase formed during decompression increased as the superheating temperature decreased from 970 to 900 °C, despite the higher number densities of pre-existing crystals before decompression in the samples with lower superheating. Such finding indicates that nucleation occurs easily when the number density is initially high. This result is inconsistent with the idea that nucleation occurs when supersaturation is sufficient to overcome the energy barrier for nucleation, and the growth of pre-existing crystals decreases supersaturation. In contrast, the results of our experiments can be explained by considering that higher superheating results in a more homogeneous melt structure with few pre-crystal clusters, which are growth sites, and ultimately the suppression of nucleation. Based on these results, we conclude that pre-existing crystals and melt homogeneity strongly affect the crystal texture formed by decompression. For application to natural systems, the high number density of microlites found in natural samples may be due to heterogeneous nucleation caused by the presence of pre-crystal clusters and other mechanisms. Furthermore, the superheating of magma in a reservoir caused by the injection of high-temperature mafic magma may influence the crystal texture during magma ascent and, hence, control the explosivity of the eruption.
EDUCAÇÃO SEXUAL DE JOVENS NA PANDEMIA COVID-19
Authors: Oliveira Caroline , Oliveira Diego , Batatinha Monalisa , Oliveira Ailton , Rocha Juliara , Suto Cleuma , Santos Maiane , De Alcântara Raquel
Published: January 2023

O estudo tem como objetivo apresentar um relato de experiência sobre as ações desenvolvidas pelo projeto de extensão de uma universidade pública, que tem o propósito de disseminar e compartilhar saberes a respeito da educação sexual de jovens. Foram utilizadas ações produzidas pelo projeto e publicados na rede social do Instagram, nas formas de posts, reels e IGTV, no período de 03/06/2021 até 08/09/2021. As atividades foram gradativamente alcançando novos públicos, de acordo com a intensificação das postagens no perfil. As/Os monitoras/es perceberam que a alimentação de espaços virtuais se apresenta como facilitador da comunicação e acolhimento em educação sexual e que as ações extensionistas podem abordar temas sensíveis e imprescindíveis à sociedade, utilizando-se de tecnologias ativas e acessíveis à população jovem.
REVITALIZAÇÃO DO NÚCLEO DE ESTUDOS EM GESTÃO E NEGÓCIOS POR MEIO DO PROJETO OXIGÊNIO
Authors: Régis Oliveira Alysson André , Silva dos Santos Allisson , Oliveira Domingos Geizyellen , Araújo Feitosa de Oliveira Aline
Published: January 2023

Desde sua constituição, em 2017, o Núcleo de Estudos em Gestão e Negócios (NEGN) perpassa por uma rotatividade de atores, principalmente de estudantes. Este trabalho teve por objetivo fortalecer a identidade do NEGN da Rede Rizoma, potencializando suas práticas extensionistas. O plano metodológico foi dividido em cinco etapas, sendo elas: (a) levantamento e atualização dos integrantes do Núcleo; (b) reunião de apresentação do núcleo para os novos integrantes; (c) atuação junto à comunidade local, (d) planejamento do NEGN e (e) atuação de algumas frentes de trabalho nas vertentes das práticas extensionistas. Foi perceptível uma mudança nos eixos da vida profissional e acadêmica dos seus participantes, trazendo a prática do curso de Administração para a realidade deles.

 

Palavras-chave: núcleo de estudos; gestão e negócios; revitalização.
DESENVOLVIMENTO PARTICIPATIVO DE SISTEMAS AGROFLORESTAIS: UMA ALTERNATIVA PARA O DESENVOLVIMENTO SUSTENTÁVEL DA AGRICULTURA FAMILIAR.
Authors: De Aguiar Maria Ivanilda , Lima Allef Matheus Holanda , Eduardo Messias João , Dos Santos Maria Joselia Gomes , Zuliani Daniela Queiroz
Published: January 2023

Sistemas Agroflorestais (SAFs) são formas de fazer agricultura que auxiliam na conservação dos recursos naturais e por isso são de grande importância para a agricultura familiar. Os SAFs são alternativas à prática de agricultura de subsistência adotada por agricultores familiares, que se caracteriza pela derrubada de toda vegetação nativa, seguido de queimada dos restos de materiais orgânicos. Esta forma de preparo da área para prática da agricultura, causa morte de animais silvestres e perda de seus habitats, degradação do solo, além de riscos de incêndios. O presente texto objetiva apresentar resultados do projeto de extensão “Desenvolvimento participativo de sistemas agroflorestais: uma alternativa para a produção sustentável da agricultura familiar” ao longo de 3 anos. O referido projeto tem como objetivo apresentar e discutir a utilização dos SAFs como forma de prática da agricultura sustentável.
MULHER COMO PROTAGONISTA DO PARTO:
Authors: Silva de França Monalisa , Suyany Guedes de Lima Evelin , Kariny Freitas Holanda de Almeida Dellis , Dantas Matias Allyne , Gomes Magalhães Adriana , Marta de Lima Costa Souza Francisca
Published: January 2023

O parto era considerado um evento natural compartilhado entre parturientes e outras mulheres da família. O objetivo deste trabalho é relatar a experiência do projeto de extensão “A mulher como protagonista do parto: Atuação Interprofissional no alívio da dor e no incentivo ao parto normal” e a percepção dos discentes participantes. Trata-se de um estudo descritivo, de abordagem qualitativa, do tipo relato de experiência. Os relatos foram desenvolvidos a partir das vivências no projeto de extensão no período de março de 2020 a dezembro de 2021, vinculado a Faculdade de Ciências de Saúde do Trairí. O projeto utilizou o Instagram, para disseminar conhecimento às mulheres que estão no período gravídico-puerperal. Ademais, recursos de comunicação permitem a partilha de informações de qualidade, além de contribuir para a formação acadêmica dos discentes participantes.
A IMPORTÂNCIA DA INSERÇÃO DE ATIVIDADES DE EXTENSÃO UNIVERSITÁRIA PARA O DESENVOLVIMENTO PROFISSIONAL
Authors: Pinheiro Jonison Vieira , Silva Narciso Christian
Published: January 2023

As atividades extensionistas em junção com as atividades de ensino e pesquisa, assumem um papel de extrema importância na construção e articulação de ideias e envolvimento da sociedade/comunidade ao qual a instituição de ensino está inserida, é definida por alguns autores como uma via de mão-dupla, pois possibilita a troca de saberes acadêmicos e populares. Este trabalho aborda conceitos e momentos históricos que marcaram a criação e aplicabilidade das atividades de extensão universitária. Por meio de uma análise sistemática na literatura e obedecendo ao objetivo principal desta pesquisa, este trabalho apresenta a importância das atividades de extensão para discentes, docentes e comunidade, e como esta contribui para o desenvolvimento profissional dos envolvidos.

Palavras-Chave: Atividades extensionistas; Universidade e Sociedade; Ensino e Pesquisa.
PROJETO ESTÍMULO:
Authors: Molari Willian Gabriel Camargo , Carlos Pinho Antonio , Maria Carvalho Ana , Vieira de Oliveira Thais , Elisa Prus Pinho Katia
Published: January 2023

A extensão é uma oportunidade oferecida pelas universidades que possibilita o discente praticar os conhecimentos adquiridos na graduação. Com caráter multidisciplinar e entrelaçado com a sociedade. O objetivo deste artigo é explanar sobre a curricularização da extensão na Universidade Tecnológica Federal do Paraná, campus Curitiba usando como base o Projeto Político do Curso Superior Tecnologia em Radiologia de 2020. que contempla uma disciplina extensionista, a Resolução do MEC e o projeto de extensão Estimulo.
AÇÕES EXTENSIONISTAS EM TEMPOS DE ADVERSIDADE
Authors: GURGEL PIRES ELOIZA , Couto Caio
Published: January 2023

Na tentativa de discutir a importância das ações extensionistas universitárias e as suas relações com os campos da Arte e da Cultura, especialmente no contexto de pandemia global ocasionado pela Covid-19 nos últimos dois anos – 2020 e 2021 –, este artigo apresenta uma reflexão sobre a experiência do Coletivo Identidade Visual, grupo vinculado ao projeto de extensão Arte, Educação e Cultura Visual: interconexões, práticas e reflexões – FFP/UERJ .

Palavras chaves: Extensão universitária, arte e cultura visual, pandemia.
Electrospun Polymer Nanofibers for Technology Applications: A Short
Review
Authors: Pathak Dinesh , Sharma Ankush , Sharma Rajesh Kumar , Nunzi J.M. , Mahajan Aman , Sharma Davinder Pal
Published: January 2023

Nanofibers are a type of nanomaterial with a diameter ranging from ten to a few hundred nanometers with a high surface-to-volume ratio and porosity. They can build a network of high-porosity material with excellent connectivity within the pores, making them a preferred option for numerous applications. This review explores nanofibers from the synthesis techniques to fabricate nanofibers, with an emphasis on the technological applications of nanofibers like water and air filtration, photovoltaics, batteries and fuel cells, gas sensing, photocatalysis, and biomedical applications like wound dressing and drug delivery. The nanofiber production market has an expected compound annual growth rate (CAGR) of 6% and should reach around 26 million US $ in 2026. The limitations and potential opportunities for large-scale applications of nano-fibrous membranes are also discussed. We expect this review could provide enriched information to better understand Electrospun Polymer Nanofiber Technology and recent advances in this field.
Opportunity of Implementing Buy the Service (BTS) Subsidies for Bus Rapid Transit (BRT) to Improve the Quality of Public Transport Services in Padang Panjang City
Authors: Masbiran Vivi Ukhwatul Khasanah , Yolarita Elsa , Wiguna Syapta , Andari Tania , Afriyanni Afriyanni , Momon Momon
Published: January 2023

This study aims to analyze the cost of subsidies and the opportunity to implement Buy the Service (BTS) for Bus Rapid Transit (BRT) in Padang Panjang City. This study uses a quantitative method with a descriptive approach. Primary data collection includes observation and distribution questionnaires with respondents using public and non-public transport users. The information obtained from the distribution of questionnaires is the origin of the destination, characteristics of public transportation behavior, and the willingness to pay of the community towards public transportation modes that follow public transportation service standards. The operational costs of public vehicles are obtained from the survey results of the basic costs of public transportation, which consist of direct and indirect costs. The results of this study formulate 3 (three) main route trajectories scenarios and cost analysis of BTS implementation that meets Minimum Service Standards (SPM). The estimated subsidy cost for implementing BTS in the three main corridors is 10.09 billion, with the highest subsidy cost being in corridor 1. which is 4.41 billion but has a smaller headway than the other two corridors. The results of this study also recommend the need for continuous socialization to the community regarding the ease and convenience of using BRT as well as equalizing perceptions between local governments and operators regarding the mechanism for providing BRT subsidies.
“Your eyes and ears on this side of the ocean”: Complicating S. J. Greenburger’s Role as Literary Scout and US Representative for Rowohlt Verlag in the 1960s
Authors: Norrick-Rühl Corinna , Razakamanantsoa Miaïna
Published: January 2023

As institutions of authorship, publishers rely on their own networks of gatekeepers and contacts to source texts from around the world for their lists. These far-flung gatekeepers can be influential and instrumental in the circulation of literature, but have remained largely invisible in the field and within literary and book historical scholarship. Using archival materials from Deutsches Literaturarchiv Marbach and Mainzer Verlagsarchiv, this contribution explores the extraordinary role of Sanford J. Greenburger as a literary scout for the German publisher Rowohlt in the 1960s. Greenburger is of particular relevance as a case study for transatlantic gatekeeping, having scouted authors and texts for Rowohlt’s prize-winning portfolio of translations from the U.S. Besides making Greenburger’s labor for Rowohlt visible and thus restructuring our understanding of Rowohlt’s U.S. interests, the contribution also offers insights into the value of publishing archives and archival research.
Back to the Sea: The Long and Winding Road of the Seagrass Species Posidonia oceanica
Authors: Cantasano Nicola
Published: January 2023

Posidonia oceanica (Linnaeus) Delile is one of the most important endemic species of the Mediterranean Sea. The long phylogenetic pathway of this species deserves special attention because its evolutionary history allows us to think back over the debated issue of life evolution on Earth. Hence, this marine plant, by terrestrial origin, was born from an ancient ancestor named Posidonia cretacea Hosius & Von der Marck. This seagrass species, currently extinct, lived in the coastal waters of the Tethys Ocean about 100 million years ago, during the geological times of the late Cretaceous. In the following Cenozoic Era, during the Miocene period, in the time lag from sixty to forty million years ago,a long process of allopatric speciation by separate areas led to eight species of Posidonia genus developed in the northern and southern hemispheres. Posidonia oceanica is established in the boreal marine regions, so representing, within the long and winding road of life evolution on Earth, a typical example of paleo-Mediterranean relict. Nowadays, Posidonia oceanica meadows perform important ecological functions in the Mediterranean Sea, not only for biodiversity conservation but also to mitigate climate change. In this way, meadows play a leading role in carbon sequestration, reducing the concentration of carbon dioxide in coastal waters. Lastly, the meadows of Posidonia oceanica promote an effective removal process of plastic debris from Mediterranean sea waters.
Iron Doped Titania/Polyaniline Composite: An Efficient Electrocatalyst for Hydrogen Evolution Reaction in Acidic Medium
Authors: Lahkar Suman , Brahma Richa , Dolui Swapan Kumar
Published: January 2023

The development of noble metal-free catalyst for hydrogen evolution reaction (HER) is the primary challenge in fuel production to replace fossil fuels. Here, we have synthesized Fe-doped TiO2/PANI nanocomposite via facile in situ polymerization method and studied its electrocatalytic activity towards HER. The composite catalyzes HER efficiently with an overpotential value of -180 mV vs. RHE in 0.5 M H2SO4 solution to achieve the current density of 10 mA cm-2 and also possesses unique stability of 8 h. However, a unique balance of PANI content must be maintained to draw the maximum efficiency from the conjuncture of active Fe-doped TiO2 particles and PANI. The catalytic efficiency of PANI is upgraded by interfacial electronic coupling with Fe-doped TiO2, due to which the antibonding states of nitrogen atom got occupied, leading to a weaker interaction between adsorbate hydrogen and catalyst surface and enhancing the rapid desorption of H2.
Examining Recruitment Strategies in the Enrollment Cascade of Youth Living With HIV: Descriptive Findings From a Nationwide Web-Based Adherence Protocol
Authors: Gurung Sitaji , Jones Stephen Scott , Mehta Kripa , Budhwani Henna , MacDonell Karen , Belzer Marvin , Naar Sylvie
Published: January 2023

Background

Digital strategies and broadened eligibility criteria may optimize the enrollment of youth living with HIV in mobile health adaptive interventions. Prior research suggests that digital recruitment strategies are more efficient than traditional methods for overcoming enrollment challenges of youth living with HIV in the United States.

Objective

This study highlights the challenges and strategies that explain screening and enrollment milestones in a national web-based adherence protocol for youth living with HIV.

Methods

Baseline data from a national web-based HIV adherence protocol for youth living with HIV, collected from July 2018 to February 2021, were analyzed. A centralized recruitment procedure was developed, which used web-based recruitment via Online Master Screener; paid targeted advertisements on social media platforms (eg, Facebook and Reddit) and geosocial networking dating apps (eg, Grindr and Jack’d); and site and provider referrals from Subject Recruitment Venues and other AIDS service organizations, website referrals, and text-in recruitment.

Results

A total of 3 distinct cohorts of youth living with HIV were identified, marked by changes in recruitment strategies. Overall, 3270 individuals consented to screening, 2721 completed screening, 581 were eligible, and 83 completed enrollment. We examined sociodemographic and behavioral differences in completing milestones from eligibility to full enrollment (ie, submitting antiretroviral therapy and viral load data and completing the baseline web-based survey). Those with the most recent viral load tests >6 months ago were half as likely to enroll (odds ratio 0.45, 95% CI 0.21-0.94). Moreover, eligible participants with self-reported antiretroviral therapy adherence (SRA) between 50% and 80% were statistically significant (P<.001 to P=.03) and more likely to enroll than those with SRA >80%.

Conclusions

The findings add to our knowledge on the use of digital technologies for youth living with HIV before and during the COVID-19 pandemic and provide insight into the impact of expanding eligibility criteria on enrollment. As the COVID-19 pandemic continues and the use of and engagement with social media and dating apps among youth living with HIV changes, these platforms should continue to be investigated as potential recruitment tools. Using a wide variety of recruitment strategies such as using social media and dating apps as well as provider referral mechanisms, increasing compensation amounts, and including SRA in enrollment criteria should continue to be studied with respect to their ability to successfully recruit and enroll eligible participants.

International Registered Report Identifier (IRRID)

RR2-10.2196/11183
Feasibility and Acceptability of Wearable Cameras to Assess Self-care in People With Heart Failure: Pilot Study
Authors: Askman Sanna , Löf Marie , Maddison Ralph , Nourse Rebecca
Published: January 2023

Background

Heart failure (HF) is a common chronic condition that affects over 26 million people worldwide. It is a progressive and debilitating disease with a broad symptom profile, intermittently marked by periods of acute decompensation. People with HF generally do not self-manage their condition well (eg, monitoring symptoms, taking medications regularly, physical activity, etc). A better understanding of self-care activities and what factors may indicate deterioration is warranted.

Objective

The aim of this study was to determine the feasibility and acceptability of using wearable cameras to assess self-care activities in people with HF. The study objectives were to (1) explore whether changes in self-care activities could be identified prior to hospitalization and (2) determine the acceptability of wearable cameras to people with HF.

Methods

A total of 30 people recently diagnosed with HF wore a camera for a maximum of 30 days; the camera took a photo every 30 seconds in the forward-facing direction. At the end of the study, all 30 participants were presented with 8 statements of acceptability, scored on a 5-point Likert scale. To determine whether camera images could identify changes in self-care activities and lifestyle risk factors before hospitalization, we analyzed images from participants (n=8) who were hospitalized during the 30-day study period. Images from the period immediately prior to hospitalization and a comparison were selected for each participant. Images were manually coded according to 9 different event categories relating to self-care and lifestyle risk factors, and events were compared between the 2 periods.

Results

The participants reported high acceptability for wearing the cameras, as most strongly agreed or agreed that they were comfortable to wear (28/30, 93%) and easy to use (30/30, 100%). The results of the camera image analysis showed that participants undertook fewer activities of daily living (P=.008) and were more sedentary (P=.02) prior to being hospitalized, compared to a period nonadjacent to hospitalization.

Conclusions

Adults with HF were accepting of using a wearable camera for periods within a 30-day time frame. Wearable cameras were a feasible approach for providing data on selected self-care activities and lifestyle risk factors for HF and offer the potential to be a valuable tool for improving our understanding of self-care.
User Engagement and Weight Loss Facilitated by a Mobile App: Retrospective Review of Medical Records
Authors: Valinskas Sarunas , Nakrys Marius , Aleknavičius Kasparas , Jonusas Justinas , Lileikienė Angelė
Published: January 2023

Background

Intermittent fasting (IF) has gained popularity in recent years for its effect on weight loss and supposed additional health benefits, such as a positive effect on body composition and metabolic markers. Mobile apps can act as platforms that help deliver dietary interventions by improving adherence and motivation. Although the effect of IF on weight loss has been demonstrated in earlier trials, there is not much research about the engagement and weight loss results with IF apps.

Objective

Our main objective was to compare how a nudging platform (including smart scales) influences engagement (the extent to which users interact with the app measured by the number of active days) with the app among users who had obesity at the beginning of use. The secondary objectives were to evaluate the body weight changes among active and nonactive users and, finally, to evaluate the body composition changes of users possessing smart scales during app usage. Through this study, we hope to provide (1) more insight into how nudging (using smart scales as a nudging platform) is associated with engagement with the mobile app, (2) how engagement with the mobile app is associated with weight loss, and (3) how IF is associated with body composition.

Methods

We performed a retrospective analysis of data from 665 users with obesity (BMI≥30) who started using the IF app DoFasting. Of them, 244 used body composition scales that estimated body fat and body muscle values. Users were stratified into engagement groups in accordance with their activity ratio (number of active days divided by the total time of use). Baseline and final users' weight (in kg), body fat (in %), and body muscle (in %) were compared.

Results

Our findings suggest an association between the nudging platform (smart scales) and better engagement with the app. Smart scale users had a significantly higher activity ratio than regular users. Additionally, active DoFasting users lost significantly more weight. Further, body composition analysis showed that app usage might be related to body fat loss and an increase in muscle mass.

Conclusions

We found a possible association between the nudging and gamified elements and higher app engagement. Additionally, increased app engagement is associated with increased weight loss. Thus, nudging and gamified elements of mobile health apps, such as interactive tools, goals, challenges, and progress tracking, are suggested to affect engagement positively and should be investigated further in future research. Finally, the IF regime delivered through the DoFasting app might be related to the body muscle mass gain and reduced fat mass.
The Effect of the COVID-19 Pandemic on Digital Health–Seeking Behavior: Big Data Interrupted Time-Series Analysis of Google Trends
Authors: van Kessel Robin , Kyriopoulos Ilias , Wong Brian Li Han , Mossialos Elias
Published: January 2023

Background

Due to the emergency responses early in the COVID-19 pandemic, the use of digital health in health care increased abruptly. However, it remains unclear whether this introduction was sustained in the long term, especially with patients being able to decide between digital and traditional health services once the latter regained their functionality throughout the COVID-19 pandemic.

Objective

We aim to understand how the public interest in digital health changed as proxy for digital health–seeking behavior and to what extent this change was sustainable over time.

Methods

We used an interrupted time-series analysis of Google Trends data with break points on March 11, 2020 (declaration of COVID-19 as a pandemic by the World Health Organization), and December 20, 2020 (the announcement of the first COVID-19 vaccines). Nationally representative time-series data from February 2019 to August 2021 were extracted from Google Trends for 6 countries with English as their dominant language: Canada, the United States, the United Kingdom, New Zealand, Australia, and Ireland. We measured the changes in relative search volumes of the keywords online doctor, telehealth, online health, telemedicine, and health app. In doing so, we capture the prepandemic trend, the immediate change due to the announcement of COVID-19 being a pandemic, and the gradual change after the announcement.

Results

Digital health search volumes immediately increased in all countries under study after the announcement of COVID-19 being a pandemic. There was some variation in what keywords were used per country. However, searches declined after this immediate spike, sometimes reverting to prepandemic levels. The announcement of COVID-19 vaccines did not consistently impact digital health search volumes in the countries under study. The exception is the search volume of health app, which was observed as either being stable or gradually increasing during the pandemic.

Conclusions

Our findings suggest that the increased public interest in digital health associated with the pandemic did not sustain, alluding to remaining structural barriers. Further building of digital health capacity and developing robust digital health governance frameworks remain crucial to facilitating sustainable digital health transformation.
A Continuous Aerobic Resistance Exercise Protocol for Concussion Rehabilitation Delivered Remotely via a Mobile App: Feasibility Study (Preprint)
Authors: Hutchison Michael G , Di Battista Alex P , Loenhart Matthew M
Published: January 2023

BACKGROUND

In recent years, several studies have consistently reported the beneficial effects of aerobic exercise in alleviating symptoms following concussion. However, exercise modality recommendations by practitioners are often limited to traditional exercise equipment (eg, treadmills and stationary bikes). Advances in digital technologies may help to overcome this limitation, as mobile apps can now provide users with high-quality instructional videos, programs, and monitoring capabilities using alternative modalities such as resistance exercises. Mobile technologies are also rapidly expanding to deliver and complement in-person clinical care. Thus, it is imperative to evaluate this emerging technology on its feasibility, safety, and clinical utility for concussion care.

OBJECTIVE

The objective of the study was to determine the feasibility of a mobile app to deliver a resistance exercise protocol with minimal equipment to individuals following concussion. Feasibility was defined by retention, adverse events, and achievement of a target heart rate (HR) of 60%±5% (age-adjusted percentage of max: 220 – age). HR data were collected using an Apple Watch, Series 6. Symptoms were evaluated before and after 3 exercise sessions.

METHODS

A 2-week, prospective, single-arm pilot study was conducted on 21 adults diagnosed with a concussion. Users were provided a continuous aerobic resistance exercise (CARE) protocol through a mobile app.

RESULTS

A total of 18 participants (14 female and 4 male) completed a 3-session exercise plan. The median age-adjusted percent of HR max for session 1 was 55.5% (IQR 49%-63%), 58.1% (IQR 50.8%-65.2%) for session 2, and 57.4% (IQR 49.5%-64.7%) for session 3. Individual median HR% across all sessions ranged from 46.9% to 67.4%; furthermore, 10 participants (55.5%) had a total mean HR% within the target HR%, 7 participants had a mean HR% below 55%, and 1 participant had a mean HR% above 65%. In addition, adherence to the plan resulted in a decrease in reported symptom burden with 94% posterior probability.

CONCLUSIONS

Following concussion, a CARE protocol delivered through a mobile app resulted in no adverse effects with 14% (n=3/21) attrition over 3 sessions. CARE was successful in achieving an aerobic exercise intensity of 55%-65% of age-adjusted maximum HR in the majority of participants and resulted in a decrease in reported symptom burden. The potential for this platform in concussion rehabilitation warrants further investigation. Future studies are needed to assess the use of this technology throughout concussion recovery in both individuals with acute concussion, and those with persistent symptoms.
A Systematic Review and Meta-Analysis Protocol of Interventions for the Patient with Prediabetes Using Mobile Health Applications (Preprint)
Authors: Jeem Yaltafit Abror , Andriani Russy Novita , Nabila Refa , Emelia Dwi Ditha , Lazuardi Lutfan , Koesnanto Hari
Published: January 2023

BACKGROUND

Individuals in a prediabetic state are much more likely to develop Type 2 diabetes mellitus (T2DM)—4 times more likely than those with normal glucose tolerance. Lifestyle changes such as daily physical activity and healthy diets can decrease the risk of a prediabetic state. Mobile application intervention could be one of the solutions to improve self-management awareness and compliance with prediabetic state intervention. There are only a few studies in systematic reviews of mobile phone application interventions to prevent prediabetes yet.

OBJECTIVE

As a result, the goal of this study was to collect and summarize evidence from randomized controlled trials (RCTs) investigating the efficacy of mobile phone applications for intervention in prediabetic patients

METHODS

This protocol was prepared in accordance with the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) statement. The database that will be used includes Clinicaltrials.gov, the International Clinical Trials Registry Platform (ICTRP), PubMed, ProQuest, and EBSCO with date restrictions between January 2007 and December 2022 in the English language only. Identification of articles will be done independently by three reviewers through the title of the articles, reviewing the abstract, and then the full-text article. Any disagreement will be resolved by consensus. The Cochrane tool will be used to assess the risk of bias. If the participants, interventions, comparisons, and outcomes are sufficiently similar, a meta-analysis will be performed. Extraction and content analysis will be performed systematically. Quantitative data will be presented graphically via forest plot with 95% confidence intervals. Where possible we will explore the heterogeneity and continue to conduct meta-analysis using the RevMan software package.

RESULTS

The proposed systematic review and meta-analyses will allow us to obtain the evidence exploring the effectiveness of mobile phone applications for intervention in prediabetic state patients.

CONCLUSIONS

Technologies (e.g., the internet, e-mail, and mobile phone applications) can provide practical, inexpensive, and scalable alternatives to traditional face-to-face procedures; this could also be applied to prediabetic patients in order to encourage lifestyle modification.

CLINICALTRIAL

This protocol has been registered in the Prospective Registry of Systematic Review (PROSPERO) database. The registration number is CRD42021243813
Faktor-Faktor Yang Mempengaruhi Pengguna Untuk Mengadopsi Teknologi Komputasi Awan Di Yogyakarta
Authors: Karpriana Angga Permadi
Published: January 2023

Penelitian ini berjudul “Faktor-Faktor yang mempengaruhi pengguna untuk mengadopsi teknologi komputasi awan di Yogyakarta” yang bertujuan untuk menguji faktor-faktor apa saja yang mempengaruhi para pengguna dalam mengadopsi atau menggunakan layanan komputasi awan di Yogyakarta. Penelitian ini fokus terhadap variabel Keamanan, Kualitas Koneksi Internet, Sikap Terhadap Penggunaan dan juga dua variabel yang terdapat dalam Technology Acceptance Model (TAM).Penelitian ini mengambil sampel para pengguna yang telah menggunakan komputasi awan di Yogyakarta. Sampel responden diambil dengan menggunakan teknik sampling aksidental, dari seluruh kuisioner yang tersebar sejumlah 150, yang dapat kembali dan diolah sebanyak 116 sampel. Pengujian dilakukan dengan menggunakan program SmartPLS ver 2.0.Dari enam hipotesis yang diujikan pada penelitian ini keseluruhan hipotesis menunjukkan hasil yang signifikan. Hipotesis tersebut menunjukkan bahwa keseluruhan variabel yang diajukan ke dalam penelitian ini mempengaruhi perilaku pengguna dalam menggunakan layanan komputasi awan.