bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential for serodiagnosis of Indonesian leprosy patients by detecting antibodies against LID-1
Authors: Herwanto Nanny , Sawitri S. , Sigit Prakoeswa Cita Rosita , Izumi Shinzo , Duthie Malcom S. , Agusni Indropo
Published: April 2019

Leprosy is caused by Mycobacterium leprae infection and remains a major public health problem in many areas of the world. The Leprosy IDRI Diagnostic (LID)-1 antigen has demonstrated potential to improve the diagnostic capacity of local health centers and aid the development of strategies for the eventual control and elimination of leprosy from endemic areas. The diagnostic capacity of LID-1 has not yet, however, been studied in Indonesia. Objective: To determine the proportion of Indonesian leprosy patients that have circulating antibodies against LID-1. Sera from thirtyfive leprosy patients from Surabaya, Indonesia were evaluated using an Enzyme Linked Immunosorbent Assay (ELISA) detecting IgG antibodies against the LID-1 antigen. Anti-LID-1 antibody levels correlated with both the clinical form of leprosy and the bacterial index (BI). LID-1-specific IgG responses were higher in multibacillary (MB) than in paucibacillary (PB) leprosy patients. Our data indicate that the detection and measurement of serum IgG against LID-1 could be an effective tool for use in control programs in various states and municipalities in Indonesia.
Development of “Deskab” as an instrument to detect scabies for non-medical personnel in Indonesia
Authors: Widaty Sandra , Krisanti Roro Inge Ade , Rihatmadja Rahadi , Miranda Eliza , Marissa Melani , Arsy Matahari , Surya Danny , Priyanto Mufqi , Menaldi Sri Linuwih
Published: April 2019

Scabies is one of the most prevalent infectious skin diseases in Indonesia, especially in boarding schools. Diagnosis of scabies can be made using the four cardinal signs through anamnesis and simple physical examination. The high incidence of scabies requires collaboration between various parties to diagnose and treat scabies. “DeSkab” (scabies detection form) is a form containing questions for non-medical personnel to detect scabies before being confirmed by trained medical personnel. Face and content validity of “DeSkab” is first established by boarding school’s supervisors, experts in community medicine, and dermatovenereologists. To establish reliability, study is conducted in Al-Hidayah Islamic Boarding School, Indonesia. Six non-medical personnel were chosen to examine 81 students of the boarding school using “DeSkab”. Each student is examined by three non-medical personnel, then confirmed through an examination by dermatovenereologists. Result of McNemar test shows that scabies detection by five nonmedical personnel have no statistically significant difference compared to the dermatovenereologist (McNemar test value of P>0.05). Based on this result, “DeSkab” proves to be an option for non-medical personnel to use as an instrument for detecting scabies in Indonesia.
Why are they hard to treat? A preliminary survey to predict important factors causing persistent scabies among students of religion-affiliated boarding schools in Indonesia
Authors: Rihatmadja Rahadi , Miranda Eliza , Wicaksono Melani Marissa , Widaty Sandra
Published: April 2019

Scabies is difficult to treat in some settings. By observation, it is highly prevalent among students of religion-affiliated boarding schools in Indonesia. Treatment often results in temporary relief. It is known that treatment alone will fail if personal hygiene and environment problems are not addressed. The aforementioned boarding schools have certain challenging characteristics, and several studies have found they might influence those problems. Our study aimed to specify and describe the characteristics to prepare future mass treatment in tackling with the problems. The study recruited and interviewed 105 students of a boarding school located in West Java region. The problems identified were sharing clothes/prayer attire among students, infrequent washing of clothes, availability of hot water, sharing beds, lack of bed sheet, and the presence of scabies among friends and siblings at home. A successful treatment plan must provide means to improve these habits.
The relationship between skin phototype, gender, and stress level with the incidence of acne vulgaris among adolescents in Surakarta
Authors: Pamungkas Ardian Hendra Rezi , Prakoeswa Flora Ramona Sigit
Published: April 2019

Acne vulgaris (AV) is formed by inflammation of the sebaceous follicles with the prevalence hits its peak during the adolescence. It can be occurred by factors including skin phototype, gender, and stress. However, there is still limited study discussing on skin phototype and the AV prevalence especially in Asian descents. Besides, it is currently unclear which factor is most influential in affecting AV. The aim of this study was to evaluate the relationship between skin phototype, gender, and stress level with the incidence of AV among adolescents. This was a cross-sectional study with 102 adolescents aged 14-18 years old as respondents. Data were collected by doctor’s examination (intra-rater, kappa=0.805) with 3 questionnaires consists of Perceived Stress Scale (PSS), Minessota Multiphasic Personality Index (MMPI-2) lie-scale, and Fitzpatrick Skin Type (FST). Chi-square test showed the significant p value (p<0.05) in all variables. Regression logistic showed gender had the greatest Odds Ratio (OR=38.610) followed by skin phototype (OR=8.226) and the stress level (OR=5.612). There was significant relationship between skin phototype, gender, and stress level with the incidence of AV among adolescents in Surakarta.
Is leukotriene B4 one of the keloid marker? a fibroblast keloid study
Authors: Kurniawati Yuli , Suwarsa Oki , Achadiyani A. , Adi Sudigdo
Published: April 2019

Keloid pathogenesis occurs due to the duration of prolonged inflammatory phase and increased production of various growth factors such as TGF-β1 which may cause increasing fibroblast proliferation and collagen synthesis. Existence of one of the chemical mediators released during inflammation, leukotriene B4 (LTB4), in keloid pathogenesis specifically in the phases of inflammation and proliferation, is still unclear. The purpose of the study is to analyze the levels of LTB4 in keloid. Methods: Fibroblast culture that was done by explanting keloid and normal skin of a keloid patient. Measurement of LTB4 on keloid and normal fibroblast was done by Elisa method. This experiment was run in triplicate. Statistical test was conducted by t test for the unpaired data and Anova test. The experiment was done at cell culture laboratory of Medical Faculty of Padjadjaran University Bandung. Levels of LTB4 in keloid fibroblast was higher than that of normal skin fibroblast (mean 23143.27 vs 18191.85 pg/ml; p<0.05). Conclusion, increased LTB4 levels in keloid fibroblast showed the existence of LTB4 role in the prolonged inflammatory process in keloid pathogenesis.
Predictor factor of inguinal lymph lode metastasis in men with penile cancer at Sanglah General Hospital, Denpasar, Bali
Authors: Yudiana I. Wayan , Duarsa Gede Wirya Kusuma , Oka Anak Agung Gde , Santosa Kadek Budi , Tirtayasa Pande Wisnu , AK Harmaya , Djatisoesanto Wahjoe
Published: April 2019

Background: To know predictor factors of inguinal node metastasis in penile cancer. Methods: A retrospective study about penile cancer in Sanglah Hospital, Bali, from 2011 to 2015. Patients had undergone partial or total penectomy, and inguinal node dissection or excisional biopsy for histopathology finding. Results: A 65 penile cancer patients were diagnosed for 5 years. Mean age was 53,24 ± 13,42 years. Fifteen were excluded and 25 of 50 patients (50%) had inguinal node metastasis. There were significant correlation between pathologic stage (p=0,021), histologic grade (p=0,020) and vascular invasion (p=0,008) with the presence of inguinal node metastasis. Primary tumor of pT1 showed 14% inguinal node metastasis compared to pT2 (42%), pT3 (67%), and pT4 (100%). Histologic grade I, had 22% inguinal node metastasis compared to grade II (50%), and grade III (100%). Only 39% patients without vascular invasion had inguinal node metastasis compared to 83% with vascular invasion. Conclusion: Pathologic stage of primary tumor, histologic grade and vascular invasion were predictor factors of inguinal node metastasis in penile cancer.
Reading the history of venereal diseases in the city: Venereal disease from Surabaya, 19th-20th century
Authors: Moordiati M.
Published: April 2019

This article aims to explore about venereal diseases that occurred in the city of Surabaya throughout the nineteenth to the twentieth century. Not much is known about what actually happened with the presence of venereal disease in the city of Surabaya throughout this period. Some existing sources are still always connected if the presence of venereal disease is more caused by prostitution activities as alleged during this time. Though it does not rule out the possibility if the disease is also caused by the consequences of others. This is presumably that became one of the reasons of this article to see if there are any reasons or other reasons to why the venereal disease can exist in Surabaya. Therefore the use of many sources (primary or secondary) is very important in this article to compare and differentiate between venereal diseases in the city of Surabaya and other cities.
Causative drugs and HLA-B polymorphism in drug-induced Stevens-Johnson syndrome - toxic epidermal necrolysis: A study in five hospitals in Jakarta
Authors: Tania Anesia , Effendi Evita Halim , Krisanti Inge Ade , Ariani Yulia
Published: April 2019

Stevens-Johnson syndrome and toxic epidermal necrolysis is a very rare but lifethreatening form of cutaneous drug eruption. In recent years, several countries in Asia had succeded in preventing carbamazepine induced SJS/TEN by screening for HLA-B*15:02 before prescribing carbamazepine. This study aimed to acquire data regarding causative drugs and HLA-B allele polymorphism in SJS/TEN patient in Jakarta. We acquired data from 5 referral hospitals from March 2015 to March 2017. Subject fulfilling the inclusion and exclusion criteria was interviewed and blood sample was taken for DNA extraction. The DNA was examined with PCR SSOP and Luminex technology for high resolution HLA-B typing. We studied 22 subjects. The median age was 45,4 years old (14-74). The most common causative drug in this study is carbamazepine. HLA-B*15:02 and HLAB* 18:01 were the most common allele in all subjects. HLA-B*15:02 was found in five (72%) out of seven subjects whose condition was caused by carbamazepine. The most common causative drug of SJS/TEN in five hospitals in Jakarta is carbamazepine, with five (72%) out seven subjects had HLA-B*15:02 allele.
The relationship between human leukocyte antigen-cw6 allele and psoriasis vulgaris
Authors: Lestari KS Sri , Darwin Eryati , Jacoeb Tjut Nurul Alam , Tjong Djong Hon
Published: April 2019

Psoriasis vulgaris is chronic skin disease that is linked to genetics and immune system. The most important predisposing genetic factor is human leukocyte antigen (HLA). This study was performed to determine the relationship between HLA-Cw6 allele and psoriasis vulgaris and the changes of nucleotide base squences, using observation method with a cross sectional comparative study. Samples were selected using consecutive sampling of 30 patients with psoriasis vulgaris attending the Dermatology and STD polyclinic at DR. M. Djamil Hospital. 30 healthy volunteers were selected as controls. The subjects’ medical history was recorded followed by a dermatological examination, collection of samples, DNA isolation, then primers were designed for HLA-Cw6 allele, genes were sequencing and finally analyzed using PCR-SSP. The results were 20% of patients with psoriasis vulgaris carried HLA-Cw6 allele, while it was absent in the control group. This difference is statistically significant at the 5% level (p = 0.024). We found the changes of nucleotide base formations of HLA-Cw6. In conclusion, based on these observations, presence of the HLA-Cw6 allele is an important genetic risk factor for developing psoriasis vulgaris.
Urinary leukotriene e4 level profile in various degrees of severity in atopic dermatitis patients in dermatovenereology outpatient clinic Dr. Soetomo General Hospital, Surabaya: A descriptive study
Authors: Pratamasari Meita Ardini , Hoetomo M. Marsoedi , Hidayati Afif Nurul
Published: April 2019

Atopic dermatitis (AD) is a chronic, relapsing skin inflammatory disease. Corticosteroid as the cornerstone treatment for AD has some flaw, especially for the chronic recalcitrant AD, since it has side effects and high possibility of rebound. Leukotriene receptor antagonist (LTRA) which has been used for asthma and allergic rhinitis now has been developed for treating AD, based on the similar mechanism of inflammation. Leukotriene (LT) is an inflammatory mediator that is thought to play role in the asthma, allergic rhinitis, and AD. Urinary leukotriene E4 (U-LTE4), the stable metabolite of LT, can be found in urine. This research aims to evaluate the role of LT in various degrees of severity in AD patients by measuring U-LTE4 levels using Enzyme Linked Immunosorbent Assay (ELISA). Twenty two AD patients who were in a flare state and came to the outpatient clinic on April – July 2017 were measured their U-LTE4 levels. The results demonstrated that mean of U-LTE4 levels increases consistently with intensity of the degree of severity, and this finding supports previous study that LT plays role in AD.
Importance of dermoscopy in diagnosis of tinea capitis: An evidence-based case report
Authors: Marina Aninda , Bianti Marsha , Widaty Sandra , Miranda Eliza
Published: April 2019

Diagnosis of tinea capitis requires direct microscopy with potassium hydroxide (KOH) staining and culture examination as the gold standard. Dermoscopy for the diagnosis of tinea capitis needs to be appraised through evidence-based case report method. A 22 years old woman came with systemic lupus erythematosus which was treated with methylprednisolone and azathioprine for a year. She had wide patchy alopecia, dry scaling, dull gray hair and minimal inflammation. KOH 20% showed septate hyphae and spores surrounding her hair shafts. Dermoscopy examination showed “comma hairs”, “corkscrew”, “perifollicular scaling” and “broken hairs”. Three articles from Pubmed and Gale fulfilled the inclusion and exclusion criteria. Articles were critically appraised and concluded that comma hairs sensitivity rate varies between 60-66% and specificity of 100%, while corkscrew had sensitivity rate varies 20-80% and specificity of 83-100%. Combination of dermoscopy with clinical performance and direct microscopic examinations amplify definitive diagnosis. Further investigations are needed to validate the role of dermoscopy as a diagnostic tool per se for tinea capitis.
Fractional laser and laser assisted corticosteroid delivery for hypertrophic scars in thermal burns
Authors: Widianingsih Ni Putu Susari , Prakoeswa Cita Rosita S.
Published: April 2019

The unprecedented survival of individuals who sustain acute burns and other trauma has increased the necessity for effective modalities in the treatment and rehabilitation of patients. Hypertrophic scars and contractures are common following thermal burns injury. Cutaneous scars can be complex and thus the approach to therapy is often multimodal with only moderate success. Intralesional corticosteroids have long been a main treatment of hypertrophic and restrictive scars. Recent advance in laser technology and applications now provide additional options for improvements in function, symptoms, and cosmesis. The ablative zones created by fractional ablative lasers may also be used in the immediate post-operative period to enhance delivery of drugs and other substances. This case report shows the successful use of fractional laser assisted corticosteroid to treat burn scars. It is need more extensive clinical trial to prove this method can be a therapeutic option for the extensive cutaneous scarring in burn patients.
The application of liposomal azelaic acid, 4-n butyl resorcinol and retinol serum enhanced by microneedling for treatment of malar pattern melasma: A case series
Authors: Kusumawardani Arie , Paramitasari Anggana Rafika , Dewi Susanti Rosmala , Betaubun Ance Imelda
Published: April 2019

Melasma is a common hypermelanosis disorder that can be frustrating both for patients and physicians because it is very difficult to treat. Azelaic acid, 4-n-butylresorcinol and retinol is some of treatment modalities for melasma, but until now there is no clinical trial studies about combination of these three agents. We reported three mixed type melasma patients whom we treated using liposomal serum containing azelaic acid, 4-n-butylresorcinol and retinol combined with microneedling. We measured the improvement with modified Melasma Severity Index (MASI), Melasma Severity Scale (MSS) and Melas-QoL quesionner. At the start of the trial the average MASI score of all patients was 5.9, MSS was moderate and Melas QoL was 55.3. We re-applied treatment every 14 days for four times. There were improvements in their MASI with the ranged of 41.7%-85%, and Melas-QoL 38.8-83.3%. All of MSS in these three patients was classified into mild in the end of therapy.
Slow responder against methotrexate 50 mg intramuscular in severe psoriatic patients: A case series
Authors: Kusumaningrum Niken , Wicaksono Danar , Winarni Dwi Retno Adi , Wirohadidjojo Yohanes Widodo , Radiono Sunardi
Published: April 2019

Methotrexate is the drug of choice used on moderate to severe psoriasis. The limited availability of oral tablet methotrexate stimulates the initiation of the protocol therapy 50 mg intramuscular methotrexate weekly in six consecutive weeks for severe psoriasis cases. There were 30 cases treated using this treatment modality. Twenty-six cases (86%) showed a good response and achieved PASI-90(Psoriasis Area Severity Index-90), four cases (13%) showed a slow response and did not achieve PASI-90. This case report collected slow response cases and identified their risk factor of slow responsiveness with this treatment modality. The comorbidity condition like metabolic syndrome, drugs induced psoriasis, continuous trauma, the side effect of methotrexate administration (ulceration), or the possibility of allergic or irritant contact dermatitis from occupation are suspected to be the risk factor for slow responders in this treatment modality.
Subcutaneous phaeohyphomycosis: A rare case
Authors: Ahmad Zahruddin , Indramaya Diah Mira , Widia Yuri , Anggraeni Sylvia , Astari Linda , Ervianti Evy , Suyoso Sunarso
Published: April 2019

Phaeohyphomycosis is a rare fungal infection caused by melanized fungi which usually involve the skin and subcutaneous tissue. It is an infrequent cause of infection in human beings. Common clinical manifestations are subcutaneous cystic swellings, which is localized, characterized by subcutaneous asymptomatic nodular lesions that develop after traumatic implantation of fungus from contaminated soil, thorns or wood splinters, especially on extremities. We report a case of subcutaneous phaeohyphomycosis presenting as multiple cystic swellings over the left lower leg with unknown predisposing factors. At first, the patient was misdiagnosed as soft tissue tumor and subcutaneous tuberculosis, then got surgical and anti-tuberculosis therapy respectively, but there was no improvement. Further investigation revealed granulomatous inflammation on histopathology examination and black-coloured colonies identifed as Exophiala dermatitidis on fungal culture. This case of phaeohyphomycosis was successfully treated by itraconazole monotherapy without surgical excision and still under follow-up.
A rare case report: Acquired vulva lymphangioma in a young female post tubercular lymphadenitis
Authors: Astari Marissa , Hidayati Afif Nurul
Published: April 2019

Lymphangioma are rare benign proliferations of the lymphatic system. Acquired lymphangioma circumscriptum of the vulva is a superficial lymphatic malformation, presenting as lymph-filled micro-to macroscopic vesicles. We describe a rare case of acquired vulva lymphangioma resulting from tubercular lymphadenitis. A 20-year-old female came to Dermatology and Venereology Outpatient Clinic of Dr. Soetomo General Hospital with chief complain there were multiple clusters vesicles on her genitalia since three months ago. The vesicles followed with discomfort and slightly itchy. There was a lymphedema on both of her inguinal since 5 years ago. She was diagnosed with tubercular lymphadenitis in 13 years old of age. No history of sexual transmitted disease. She had 5 times of cryotherapy and it nearly got remission.
Utilization of Small RNA Genes to Distinguish Vibrio cholerae Biotypes via Multiplex Polymerase Chain Reaction
Authors: Ahmed Siti Aminah , Raabe Carsten A. , Cheah Hong Leong , Hoe Chee Hock , Rozhdestvensky Timofey S. , Tang Thean Hock
Published: April 2019

The diarrheal disease “cholera” is caused by Vibrio cholerae, and is primarily confined to endemic regions, mostly in Africa and Asia. It is punctuated by outbreaks and creates severe challenges to public health. The disease-causing strains are most-often members of serogroups O1 and O139. PCR-based methods allow rapid diagnosis of these pathogens, including the identification of their biotypes. However, this necessitates the selection of specific target sequences to differentiate even the closely related biotypes of V. cholerae. Oligonucleotides for selective amplification of small RNA (sRNA) genes that are specific to these V. cholerae subtypes were designed. The resulting multiplex PCR assay was validated using V. cholerae cultures (i.e., 19 V. cholerae and 22 non–V. cholerae isolates) and spiked stool samples. The validation using V. cholerae cultures and spiked stool suspensions revealed detection limits of 10–100 pg DNA per reaction and 1.5 cells/mL suspension, respectively. The multiplex PCR assay that targets sRNA genes for amplification enables the sensitive and specific detection, as well as the differentiation of V. cholerae—O1 classical, O1 El Tor, and O139 biotypes. Most importantly, the assay enables fast and cheaper diagnosis compared with classic culture-based methods.
Interactions between Parasitic Infections and the Human Gut Microbiome in Odisha, India
Authors: Huwe Tiffany , Prusty Birendra Kumar , Ray Aisurya , Lee Shaun , Ravindran Balachandran , Michael Edwin
Published: April 2019

Soil-transmitted helminth (STH) infections and malaria are parasitic diseases with enormous global health burdens. Research has demonstrated a relationship between each of these parasites and the gut microbiome, suggesting that the gut microbiota may be implicated in governing host susceptibility to diverse pathogens, and perhaps even coinfection by different pathogens, through similar microbiome-influenced pathways. Here, we have derived a first microbiome community profile associated with STH infections in Odisha, India, and tested the hypothesis that the gut microbiome can modulate host susceptibility to multiple parasite infections through the same pathways. This study revealed several bacterial taxa negatively associated with specific STH infections, including Lactobacillus and Lachnospiracaea. Our results also suggest that relative abundance of Lactobacillus is driven by the STH infection status more so than by the Plasmodium infection status. This study contributes to efforts to understand the effects of the microbiome on host susceptibility to parasitic infections in endemic communities.
A Decentralized Context Broker Using Byzantine Fault Tolerant Consensus
Authors: Ramachandran Venkatapathy Aswin Karthik , Ten Hompel Michael
Published: April 2019

A context broker is a reliable message-relaying service used to connect devices by integrating all device protocols and communication methods, and reliably transporting messages while isolating data from other application service layers and networking complexities. A highly scalable decentralized context broker stack is composed of three layers—starting with a peer-to-peer network connecting a byzantine fault-tolerant (i.e., blockchain-based) consensus protocol—and it manages the communication using a web-socket streaming protocol as interface to other applications. This paper presents such a concept for a decentralized context broker stack for intercommunication between heterogeneous materials handling systems, and deploys the stack as proof-of-concept using ROS-based robots in a logistics scenario.
Environmental Education and Energy Efficiency as Strategies for Reducing Energy Consumption in Public School Building in Goiânia
Authors: Rosa Marlison Noronha , Sousa Yan Machado , Hora Karla Emmanuela Ribeiro , Kopp Katia , Junior Getulio Antero de Deus
Published: April 2019

Electrical energy is essential for the quality of life of people, who use it in different socioeconomic activities and for technological development. In view of the gradual increase in the demand for electricity and the future possibility of not serving all the consumer sectors, it is necessary to optimize it. The objective of this study was the application of strategies based on the pillars of energy efficiency and environmental education in order to minimize the expenditure of electric energy in public buildings, which were selected for this project due to the fact that, its users show a lack of concern about the correct consumption of electric energy since the expenses are tied to the public coffers and are not always perceived by the people as resources coming from the taxes paid by the citizens. Among the public buildings that consume the most electric energy, the most important are those in the education sector. In fact, a larger project called the Energy Efficiency Project in Public Buildings in Goiânia (PEEEPG), to which this work is linked, found that among the municipal public buildings, the education sector is responsible for approximately 30% of the electricity consumption and, therefore, this specific sector was selected for the application of the selected strategies. The methodology used was based on research-participant, environmental education together with replacement of lamps by LED system (Light Emitting Diode) at strategic locations in the building and monitoring of results. The actions carried out included the lamp replacement, and educational lectures offered to students of different age groups in three school shifts with a partnership of employees and teachers of the municipal school selected on energy efficiency and strategies to reduce the consumption of electricity. The project mobilized directly about 200 people belonging to the target audience and indirectly 800 students who were part of the teaching unit. It was collected a data base among 2012 to 2016. The methods of data collection and analysis were based on documentary research, analyzing the electric energy bills of the building, as well as documents and legislation of the municipality itself on the consumption of electric power and the architecture model applied to school environments in Goiânia. The results obtained, after a monitoring period of six months (November to April) during the years 2016 and 2017, indicated an analyze to reduction of 16% of the consumption of electric energy in the building, compared to the same period in the previous year. Therefore, this result regard to the possibility of investments in energy efficiency projects for public buildings, subsidizing actions in the design, retrofit and maintenance of public buildings.
Análise praxiológica do voleibol sentado: elementos para o processo de ensino-aprendizagem a partir da lógica interna
Authors: Fagundes Felipe Menezes , Ribas João Francisco Magno
Published: April 2019

Esse ensaio objetiva identificar os elementos relevantes da lógica interna do Voleibol Sentado para o processo de ensino-aprendizagem. A partir de uma pesquisa teórica e de uma análise praxiológica, evidenciou-se características do Voleibol Sentado, com base em artigos científicos sobre o tema e pela ferramenta de análise Universais da Praxiologia Motriz. Como resultados, salienta-se o protagonismo das interações motrizes para organização do jogo e atuação dos jogadores, a necessidade de conhecer as possibilidades de ação dos papeis e subpapeis e a pertinência da leitura de jogo e da interpretação dos comportamentos motores. Por fim, sintetizou-se esses conhecimentos referentes a lógica interna do Voleibol Sentado para o processo de ensino-aprendizagem para além do tecnicismo.
Descolonização de sujeitos monstros no game Undertale: uma reflexão com a psicologia social.
Authors: Serra Arthur Galvão , Da Rosa Marcelo Victor
Published: April 2019

Este artigo tem por objetivo apresentar contribuições de três autores clássicos das teorias críticas dos discursos colonialistas, fazendo reflexões a partir da análise do game Undertale. O primeiro autor, Franz Fanon, fornece aportes para o entendimento da ação descolonizadora na produção de subjetividades. O Orientalismo de Edward Said aponta para discursos científicos legitimadores da colonialidade e a institucionalização da psicologia científica no Brasil. Por fim, Mohandas Gandhi problematiza estratégias de resistência situadas de violência e não-violência. Com a análise das trajetórias de descolonização, o jogo Undertale e as estratégias relacionadas aos autores possibilitaram abertura na cristalização da colonização do outro e sua legitimação pela bestialização.
Truth, Only More So: Bances Candamo Beyond the Limits of Embodiment
Authors: Slater John
Published: April 2019

Bances’ Theatro de los theatros is, without question, an exceedingly odd work of expository prose. However, there are reasons we should try to understand what Bances is up to if we want to understand early modern Spanish drama better, both from a historical perspective and from the perspective of performance. This is because Bances’ real object is the nature of theatrical representation and the nature of what, exactly, is embodied through performance. Bances does not argue that theater is a mirror of life, or that theater is life as it might be, or that theater indicates the reality of something true beyond itself. Instead, Bances says that the staging of a play manifests physically the physical reality of the universe.
The Tangible/Intangible Dialectic inLa dama duende: A Critical Appreciation of the CNTC’s 2017 Production
Authors: Ocampo Eduardo Paredes
Published: April 2019

The CNTC’s 2017 production of La dama duende presented the transition between the two main characters’ rooms in the third jornada using two illuminated windows at the rear wall of the stage. The comparison between this rendition and other modern productions reveals two problems in adaptation: the fidelity with the original and the understanding of contemporary audiences. In contrast, textual analysis sets the main aspects in which original performance was based. The work highlights the centrality of the tangible/intangible dialectic in connecting the many elements of play: the set, the theme, and the audience’s spatial cognition. Synecdoche (in the vestuario) was a featured tool in the audience’s conception of space of the corral. By changing the usage of this trope for the windows solution, the CNTC’s version failed to address the tangible/intangible dialectic of Calderón’s original. Consequently, the adaptation disregarded both the tradition and the public’s participation in the performance.
Awareness and source of AIDS-related prevention knowledge among medical university students of Guizhou province, China
Authors: Zhou Yanna , Yang Wanjin , Wang Xue , Wang Haiyan , Zhu Deyu , Shi Xiuquan
Published: April 2019

Objective: To clarify the awareness and source of AIDS knowledge among college students of medical university of Guizhou province, China, so as to provide some basic evidences for implementing education of AIDS control and prevention .Methods: A stratified cluster sampling survey was conducted. Self-designed questionnaires were used to investigate university students, Epidata 3.0 and SPSS 8.0 were used to analyze data.Results: The awareness rate of AIDS through blood transmission and mother-to-child transmission was over 90%, the awareness rate of sexual transmission was just about 80%, and the awareness rate of non- transmission route “mosquito bites will not spread AIDS” was only 53.3%. The awareness rate of AIDS transmission and treatment among medical students was higher than that of non-medical students. The Internet, propaganda materials, newspapers and magazines, and school classes were the main ways for university students to acquire AIDS knowledge. Some students hope to acquire knowledge from classmates and friends, it was found that the proportion of medical students receiving AIDS knowledge from school classes was significantly higher than that of non-medical students (80.8% vs 73.1%, p = .007).Conclusion: Though the awareness rate of AIDS knowledge among medical students is better than that of non-medical students, they had incomplete knowledge of AIDS, especially the sexual transmission. Moreover, school classes may be an effective way to propagandize AIDS-related knowledge, so schools can consider publicizing the AIDS education through classes, so as to improve students’ abilities of AIDS control and prevention.
Reliability of International Classification of Disease-9 Versus International Classification of Disease-10 Coding for Proximal Femur Fractures at a Level 1 Trauma Center
Authors: Schneble Christopher A. , Natoli Roman M. , Schonlau Duane L. , Reed R. Lawrence , Kempton Laurence B.
Published: April 2019

Introduction:

The Centers for Medicare & Medicaid services proposed that transitioning from the 9th to the 10th revision of the International Classification of Disease (ICD) would provide better data for research. This study sought to determine the reliability of ICD-10 compared with ICD-9 for proximal femur fractures.

Methods:

Available imaging studies from 196 consecutively treated proximal femur fractures were retrospectively reviewed and assigned ICD codes by three physicians. Intercoder reliability (ICR) was calculated. Collectively, the physicians agreed on what should be the correct codes for each fracture, and this was compared with coding found in the medical and billing records.

Results:

No significant difference was observed in ICR for both ICD-9 and ICD-10 exact coding, which were both unreliable. Less specific coding improved ICR. ICD-9 general coding was better than ICD-10. Electronic medical record coding was unreliable. Billing codes were also unreliable, yet ICD-10 was better than ICD-9.

Discussion:

ICD-9 and ICD-10 lack reliability in coding proximal femur fractures. ICD-10 results in data that are no more reliable than those found with ICD-9.

Level of Evidence:

Level I diagnostic
Competències digitals i comunicatives docents: una entrevista amb la Dra. Dolors Masats
Authors: Pratginestós Cèlia
Published: April 2019

Entrevista amb la Dra. Dolors Masats.
Effect of chipping and scoring techniques on bulb production of Lachenalia cultivars
Authors: Kapczyńska Anna
Published: April 2019

The genus Lachenalia (Asparagaceae) represents spectacular and botanically diverse ornamental, bulbous species originating from Southern Africa. The main aim of this study was to determine, for the first time, the possibility of propagation of lachenalia cultivars (‘Namakwa’, ‘Rainbow Bells’, ‘Rupert’) by two in vivo techniques: chipping and scoring, which can be applied in procedures of bulb production. In the second part of the experiment, the plant growth and the quality of bulblets after the first season of cultivation in a greenhouse were estimated. The survival ability of bulb-scale segments and scored bulbs of the tested cultivars ranged from 62% to 95%. Chipping method generated eight bulblets per mother bulb with an average weight and diameter of 0.17 g and 0.29 cm, respectively, while scoring two/three bulblets per mother bulb with an average weight and diameter of 0.28 g and 0.5 cm, respectively. In the first season of cultivation, bulblets obtained by chipping produced longer leaves than those obtained by scoring technique. Only bulblets of ‘Rupert’ obtained by scoring showed the capacity to flower (‘Namakwa’ and ‘Rainbow Bells’ remained in a juvenile phase). When assessing the bulb yield after the first season of cultivation, it was found that irrespective of cultivar, bulbs obtained by chipping achieved twice the weight coefficient of those obtained by scoring.
Apelin as a nociceptive processes regulator
Authors: Kujacz Joanna , Mika Joanna
Published: April 2019

The aim of this paper is to characterize the biologically active peptide – apelin, and its previously identified APJ receptor. Gene and protein expression of apelin/APJ system has been detected in many tissues and organs of the body such as: adipose tissue, stomach, liver, pancreas, heart, lungs, uterus, ovaries, brain or spinal cord. The results of recently published papers show the role of the apelin/APJ system in numerous physiological and pathological processes in the body, including nociceptive processes. This paper discusses the physiological and molecular mechanisms of the apelin/APJ system, with particular emphasis on its role in inflammatory and neuropathic pain, as well as in the effectiveness of opioids. In addition, the clinical aspect of this system in pain processes is presented.
Amy-Jill Levine and Ben Witherington. III The Gospel of Luke
Authors: Gilbert Gary
Published: April 2019

No abstract is available.
MODEL FOR THE ANALYSIS OF INTRALAMINAR THERMAL STRESSES IN LAMINATED COMPOSITES MATERIALS
Authors: DELFIN VAZQUEZ JUAN JOSE , ACOSTA FLORES MARIO , JIMENEZ LOPEZ EUSEBIO , LUCERO VELAZQUEZ BALDOMERO , MONTIEL GONZALEZ MOISES
Published: April 2019

When a structural element is manufactured with a laminated composite material (MCL) and this is subjected to temperature changes, intralaminar thermal stresses are generated. The intralaminar thermal stresses occur due to the differences among the coefficients of thermal expansion and the elastic properties of the layers that make up the MCL. It is possible that a combination of intralaminar stresses and mechanical stresses will produce faults by separation in the MCL layers (delamination).
In this article we presents an analytical model with which global and intralaminar thermal stresses produced by temperature changes induced in symmetric metallic MLCs are calculated, without restrictions at the borders. The model is fed by deformation data obtained by strain gauges placed at the border of the MLC. The model can be used in the determination of intralaminar and global stresses considering restrictions or loads at the border, only if the problem is of flat stresses.
The model was developed by making an analogy to the analytical model developed in [1], which consists of calculating intralaminar and global stresses that are generated by the difference between the elastic constants of the materials that make up an MCL subjected to simple tension. The proposed model is based on the theory of linear elasticity, the classical theory of plates and the principle of superposition.
With the model and through an array of experimental tests, the coefficients of thermal expansion (CET) of each of the layers can be calculated. Finally, experimental validation tests were carried out which showed that the proposed model is reliable and consistent.

Keywords: Thermal stress, intralaminar stress, Thermal Expansion Coefficient, Composite Materials.
INTELLIGENT ELECTRICITY NETWORK IN THE TECHNICAL UNIVERSITY OF MANABÍ AND ITS ECONOMIC AND ENVIRONMENTAL IMPACT
Authors: LLOSAS  ALBUERNE YOLANDA , BALDERRAMO VELEZ NEY RAUL
Published: April 2019

Intelligent electricity grids are the main energy management strategy worldwide. Bearing in mind that one of the major problems presented as a global challenge, is the generation and use of electricity, while protecting the environment.
Diagnostic value of magnetic resonance imaging using superparamagnetic iron oxide for axillary node metastasis in patients with breast cancer: a meta-analysis
Authors: Lee Ru Da , Park Jung Gu , Ryu Dong Won , Kim Yoon Seok
Published: April 2019

Objectives Identification of axillary metastases in breast cancer is important for staging disease and planning treatment, but current techniques are associated with a number of adverse events. This report evaluates the diagnostic accuracy of superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging (MRI) techniques for identification of axillary metastases in breast cancer patients. Methods We performed a meta-analysis of previous studies that compared SPIO enhanced MRI with histological diagnosis after surgery or biopsy. We searched PubMed, Ovid, Springer Link, and Cochrane library to identify studies reporting data for SPIO enhanced MRI for detection of axillary lymph node metastases in breast cancer until December 2013. The following keywords were used: “magnetic resonance imaging AND axilla” and “superparamagnetic iron oxide AND axilla”. Eligible studies were those that compared SPIO enhanced MRI with histological diagnosis. Sensitivity and specificity were calculated for every study; summary receiver operating characteristic and subgroup analyses were done. Study quality and heterogeneity were also assessed. Results There were 7 publications that met the criteria for inclusion in our meta-analysis. SROC curve analysis for per patient data showed an overall sensitivity of 0.83 (95% Confidence interval (CI): 0.75–0.89) and overall specificity of 0.97 (95% CI: 0.94–0.98). Overall weighted area under the curve was 0.9563. Conclusions SPIO enhanced MRI showed a trend toward high diagnostic accuracy in detection of lymph node metastases for breast cancer. So, when the breast cancer patients has axillary metastases histologically, SPIO enhanced MRI may be effective diagnostic imaging modality for axillary metastases.
A study of the effectiveness of using the serum procalcitonin level as a predictive test for bacteremia in acute pyelonephritis
Authors: Lee Ga Hee , Lee Yoo Jin , Kim Yang Wook , Park Sihyung , Park Jinhan , Park Kang Min , Jin Kyubok , Park Bong Soo
Published: April 2019

Objectives Serum procalcitonin (PCT) is a specific biomarker that rises after bacterial infection, and levels of PCT are known to correlate with the severity and mortality of patients with pneumonia and sepsis. However, the usefulness of PCT levels in acute pyelonephritis is unknown. This study aimed to evaluate the effectiveness of using the PCT level as a predictive test for bacteremia in acute pyelonephritis. Methods Between January 2012 and June 2013, 140 patients diagnosed with acute pyelonephritis were admitted to Haeundae Paik Hospital. Serum PCT, C-reactive protein (CRP), and white blood cell (WBC) levels at pre- and post- treatment were measured. Blood and urine cultures were obtained from all patients. The levels of PCT, CRP, and WBCs were each compared between the blood culture-positive and blood culture-negative groups to assess their effectiveness in predicting bacteremia. Results Pre-treatment PCT level was 0.77 ng/mL (95% CI: 0.42–1.60 ng/mL) in the blood culture-negative group and 4.89 ng/mL (95% CI: 2.88–9.04 ng/mL) in the blood culture-positive group, and the increase between the two groups was statistically significant. The area under the receiver operating characteristic curve of PCT level for prediction of bacteremia was 0.728. A cut-off value of 1.23 ng/mL indicated a sensitivity of 79.0 % and specificity of 60.0 % for PCT level. Conclusions Serum PCT level is a useful predictive test for bacteremia in acute pyelonephritis. Through the early detection of bacteremia, serum PCT level can help estimate the prognosis and predict complications such as sepsis.
Case of hyperosmolar hyperglycemic state by a sodium-glucose cotransporter 2 inhibitor
Authors: Nho In-Young , Kim Hae-Sung , Kang Nam-Kyu , Lee Myung-Won , Kim Soo-Kyung , Park Seok-O
Published: April 2019

Inhibitors of sodium-glucose cotransporters type 2 (SGLT2) are proposed as a novel approach for the management of type 2 diabetes mellitus. SGLT2 cotransporters are responsible for reabsorption of 90 % of the glucose filtered by the kidney. The glucuretic effect resulting from SGLT2 inhibition contributes to reduce hyperglycaemia and also assists weight loss and blood pressure reduction. In this study, we presented the case of a 59-year-old male who developed hyperosmolar hyperglycemic state (HHS), possibly caused by a sodium-glucose cotransporter 2 (SGLT2) inhibitor, a novel class of antihyperglycemic agents. This case highlights that HHS can develop in patients with diabetes treated with SGLT2 inhibitors
A Case of Spontaneous Common Iliac Atery Dissection
Authors: Noh Juho , Rhee Il , Kim Minsung , Lee Jonghyun , Kim Kisu , Park Byungwhan
Published: April 2019

Spontaneous and isolated dissection of the limb arteries without involvement of the aorta is extremely rare, and has been reported previously in pregnant patients in association with collagen vascular disease, and in cases of high-energy trauma or intensive activity in athletes. There is no consensus yet on indications for medical or surgical therapeutic modality. Due to the rarity of spontaneous dissection of external iliac artery, its natural history has been poorly described. A healthy 50-year-old male with normotension was admitted with an acute onset of left flank pain. Left external iliac artery dissection was diagnosed by abdominal computed tomography.
Does Immobilization Affect Braking Time?
Authors: Schick Faith A , Karanjia Homyar , Taweel Nicholas , Langman Charles , Sullivan Paul
Published: April 2019

Background:

Despite the importance to patients of driving, no well-established guideline exists to help either the patient or the physician determine when it is safe for the patient to return to driving. Previous studies have recommended 6 weeks postoperatively before patients can return to driving safely. Several scientific studies have found the nationally recommended safe brake time standard to be 1.25 sec (1,250 msec), looking at brake reaction time (BRT) in all types of patients, surgical and nonsurgical.

Methods:

This is a prospective study assessing BRT after individuals are placed in various forms of immobilization (controlled action motion [CAM] boot, surgical shoe). The study also tested whether BRT is different when using the left foot to brake, with immobilization of the right foot.

Results:

All 29 male and 71 female participants in this study (mean age, 35.49 years) were capable of driving and were not currently being treated for any foot or ankle conditions. No differences were found regarding age, sex, and use of assistive devices. The mean BRT while wearing a CAM boot was 713 msec, while using the left foot to brake (CAM boot on the right foot) was 593.86 msec, and while wearing a surgical shoe was 626.32 msec.

Conclusions:

Although most of the study participants were below the nationally recommended safe brake time standard, it was found that not all of the participants fell within these parameters.