bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of 3D Printing Parameters on the Mechanical Behavior of PLA
Authors: Enache Ioana-Catalina , Cristina Ioana-Madalina , Chivu Oana-Roxana , Mates Ileana , Ionita Elena , Geambasu Gabriel
Published: April 2024

Additive technologies are continually evolving and are crucial in numerous industries, including medical, aerospace, and automotive, but they can also play an important role in the prototyping phase. Due to additive manufacturing, amateurs and enthusiasts can construct simple projects as well as large projects with specialized usage in specific applications. When it comes to complex pieces, traditional manufacturing technologies such as milling, chipping, drilling, and so on have specific constraints, often need even additional production processes to complete the item. All of these constraints can be solved with additive technologies. This work investigates Fused Deposit Modeling (FDM) printing of many specimens with varying properties in order to analyze PLA (Poly Lactic Acid) material behavior following tensile testing. The collected findings will be analyzed in order to determine the specimens with the most significant behavior according on the modified parameters.
Teaching Programming to Schoolchildren in Gomel (Belarus)
Authors: Dolinsky Michael
Published: April 2024

The author has been teaching programming to Gomel schoolchildren for more than four decades. For the last twenty-five years, training has been focused primarily on preparing for programming competitions from school to international competitions (IOI). Since 1997, 15 students of the author have won a total of 26 medals at IOI 1997 - 2023. The article contains a description of the teaching methods and tools used by the author. An essential technical basis for training is the instrumental distance learning system DL.GSU.BY, was created and developed under the leadership of the author from 1999 to the present time.
Risk factors for lymph node metastasis in superficial esophageal squamous cell carcinoma
Authors: Yu Yan-Bo
Published: April 2024

In this editorial, we comment on the article by Wang et al published in the recent issue of the World Journal of Gastroenterology in 2023. We focused on identifying risk factors for lymph node metastasis (LNM) in superficial esophageal squamous cell carcinoma (SESCC) patients and how to construct a simple and reliable clinical prediction model to assess the risk of LNM in SESCC patients, thereby helping to guide the selection of an appropriate treatment plan. The current standard treatment for SESCC is radical esophagectomy with lymph node dissection. However, esophagectomy is associated with considerable morbidity and mortality. Endoscopic resection (ER) offers a safer and less invasive alternative to surgical resection and can enable the patient's quality of life to be maintained while providing a satisfactory outcome. However, since ER is a localized treatment that does not allow for lymph node dissection, the risk of LNM in SESCC limits the effectiveness of ER. Understanding LNM status can aid in determining whether patients with SESCC can be cured by ER without the need for additional esophagectomy. Previous studies have shown that tumor size, macroscopic type of tumor, degree of differentiation, depth of tumor invasion, and lymphovascular invasion are factors associated with LNM in patients with SESCC. In addition, tumor budding is commonly associated with LNM, recurrence, and distant metastasis, but this topic has been less covered in previous studies. By comprehensively evaluating the above risk factors for LNM, useful evidence can be obtained for doctors to select appropriate treatments for SESCC patients.
Molecular insights into clinical trials for immune checkpoint inhibitors in colorectal cancer: Unravelling challenges and future directions
Authors: Sharma Samantha , Singh Naresh , Turk Anita Ahmed , Wan Isabella , Guttikonda Akshay , Dong Julia Lily , Zhang Xinna , Opyrchal Mateusz
Published: April 2024

Colorectal cancer (CRC) is a complex disease with diverse etiologies and clinical outcomes. Despite considerable progress in development of CRC therapeutics, challenges remain regarding the diagnosis and management of advanced stage metastatic CRC (mCRC). In particular, the five-year survival rate is very low since mCRC is currently rarely curable. Over the past decade, cancer treatment has significantly improved with the introduction of cancer immunotherapies, specifically immune checkpoint inhibitors. Therapies aimed at blocking immune checkpoints such as PD-1, PD-L1, and CTLA-4 target inhibitory pathways of the immune system, and thereby enhance anti-tumor immunity. These therapies thus have shown promising results in many clinical trials alone or in combination. The efficacy and safety of immunotherapy, either alone or in combination with CRC, have been investigated in several clinical trials. Clinical trials, including KEYNOTE-164 and CheckMate 142, have led to Food and Drug Administration approval of the PD-1 inhibitors pembrolizumab and nivolumab, respectively, for the treatment of patients with unresectable or metastatic microsatellite instability-high or deficient mismatch repair CRC. Unfortunately, these drugs benefit only a small percentage of patients, with the benefits of immunotherapy remaining elusive for the vast majority of CRC patients. To this end, primary and secondary resistance to immunotherapy remains a significant issue, and further research is necessary to optimize the use of immunotherapy in CRC and identify biomarkers to predict the response. This review provides a comprehensive overview of the clinical trials involving immune checkpoint inhibitors in CRC. The underlying rationale, challenges faced, and potential future steps to improve the prognosis and enhance the likelihood of successful trials in this field are discussed.
The Principle of Cooperation in Service Communication Conversations
Authors: Deavisca Kenza Viorel , Iswatiningsih Daroe , Faizin Faizin , Setiawan Arif
Published: April 2024

This research aims to (1) describe the form of compliance and language function of the principle of cooperation in service communication conversations at the Muhammadiyah University of Malang Library, 2) describe violations and factors that influence the principle of cooperation in service communication conversations at the Muhammadiyah University of Malang Library. This type of research method is qualitative with a case study research approach. The research data is about the principles of cooperation in service communication conversations at the Muhammadiyah University of Malang Library. The data source comes from primary data sources in the form of dialogue text fragments in recorded service communication conversations that occurred between students and library staff at the University of Muhammadiyah Malang. The data collection technique was carried out using the note-taking method. Then, the data analysis technique is carried out by analyzing the data by reducing the data, presenting the data, and drawing conclusions. The results of the research analysis show (1) there are four forms of compliance with the maxims of cooperation principles, which include the maxim of quantity, the maxim of quality, the maxim of relevance, and the maxim of manner. There are two language functions found in compliance with these maxims, including assertive and directive language functions. The function of assertive language, namely stating, is found in the maxim of quantity and the maxim of quality, while the function of directive language, namely commanding, is found in the maxim of relevance and the maxim of manner, (2) there are two forms of violation of the maxim of the principle of cooperation which include the maxim of quantity and the maxim of relevance. There are also factors that influence the occurrence of violations of these maxims. Violations that occur in the maxim of quantity are influenced by situational factors and conditions that are being experienced. Meanwhile, violations of the maxim of relevance are influenced by the lack of known information.
The Implementation of Punishment Method in Strengthening the Discipline of Students in Islamic Boarding School
Authors: Rambe Mangaraja Sinomba , Noviandi Riki , Najib Muh Ainun , Khoirunisa Tutik , Sopian Hilmi , Azhari Novi Nurjannah
Published: April 2024

This research aims to explore the implementation of the punishment method as a strategy to strengthen the discipline of students at the Darussalam Parmeraan Islamic Boarding School. This research uses a descriptive qualitative research method through a case study approach related to the implementation of punishment in strengthening student discipline at the Darussalam Parmeraan Islamic boarding school, Dolok sub-district, North Sumatra province. This data collection technique starts with planned observations related to the implementation of punishment to increase the discipline of students. Then, the researcher conducted structured interviews with several teaching staff and student leaders (OSIS), including informants A, B, - N, and informant R. After the data was collected, the researcher would reduce the data, analyze it carefully, and then conclude that it was valid. The research results show that the method of administering punishment has been integrated and applied systematically as the main instrument in building Santri discipline in the Islamic boarding school environment. The Darussalam Parmeraan Islamic Boarding School adapts a balanced approach between educational and humanistic punishments to achieve the goal of developing the character of its students, especially by increasing discipline. The punishment applied to disciplinary violators will be adjusted to the level of error, with a reflection of religious norms and holistic concepts as the main basis for implementing this method of punishment. It can be concluded that punishing violators of regulations is considered very effective as a means of strengthening the discipline of students living their lives in the Islamic boarding school environment. With the existence of rules and consequences, students are more likely to comply with the norms and values that apply in Islamic boarding schools as part of the character education process.
The Development of E-Learning Using Multimedia-Based GIS E-Modules
Authors: Supuwiningsih Ni Nyoman , Parwati Ni Nyoman , Suharta I Gusti Putu , Tegeh I Made
Published: April 2024

The aim of this research is to develop an interactive, interesting, effective, and fun multimedia-based e-module for the Geographic Information Systems (GIS) course, which can be accessed online so that it can improve student learning outcomes in e-learning via Moodle LMS. The research method employed is the Research and Development (R&D) method. The research method used is the research and development method, which has been modified by Sukmadinata and consists of a preliminary study stage, a model development stage, and a model test stage. The data used in this research is primary data, a population of teaching lecturers who are experts in teaching Geographic Information Systems courses as an e-module trial. The second primary data is the respondent population of ITB STIKOM Bali students who took the Geographic Information Systems course. The sample used in this study was a simple random sample of students registered to take these courses. The data collection technique used in this research used a Likert scale questionnaire instrument for e-module testing. The questionnaire analysis technique uses the feasibility percentage formula. To determine the effectiveness of the e-module, give a test to a sample of students before and after using the e-module by using the N-gain formula in data analysis. The research findings indicate that the e-module is suitable for use as a learning resource, as it received a positive evaluation from the lecturers who used it, with an average score of 48.5 or 88.2% in the "excellent" category based on Likert scale responses in the questionnaire. Additionally, the e-module is effective for student learning, as evidenced by the N-Gain score of 0.74, with a value greater than 0.7, indicating a high level of effectiveness.
RECONNAISSANCE AND STRIKE SYSTEMS IN NETWORK-CENTRIC WARFARE
Authors: Ivanov D. , Oliinyk R. , Zhivetc Yu. , Ivanova V.
Published: April 2024

The article reveals the essence of the concept of network-centric warfare, outlines the main requirements for network-centric military control systems when they are used in modern wars (combat operations) to ensure automated control of high-tech armed forces. This article examines the current state and prospects for the development of intelligence-strike systems. Reconnaissance and strike systems are key elements of modern military operations, providing the ability to conduct reconnaissance missions and conduct strikes against enemy targets. The article analyzes modern reconnaissance and strike systems, including unmanned aerial vehicles, cruise missiles and other means. Their technical characteristics, possibilities and limitations are studied. Also considered are the main challenges and trends that affect the development of intelligence-strike systems, such as the expansion of the use of artificial intelligence and the increase of autonomy of systems. This article examines the role of intelligence-strike systems in the context of network-centric warfare. In modern military conflicts, where information technology and network interaction play a key role, reconnaissance and strike systems are becoming an integral part of strategic planning and combat effectiveness. The article analyzes the impact of network-centric warfare on intelligence and strike systems. The main characteristics and requirements for these systems for effective operation in the conditions of network warfare are considered. The latest technologies that can increase the effectiveness of intelligence-strike systems in such conditions are being investigated, including artificial intelligence, data analytics and autonomy. Based on the analysis, the article provides recommendations for the further development of reconnaissance and strike systems. Ways to improve their effectiveness, to ensure better coordination between reconnaissance and strike functions, and to ensure greater security and resistance to enemy countermeasures are proposed. The presented material should be used both by the management staff and scientists of the armed forces when developing operational-tactical requirements for network-centric management systems of military purpose, as well as by management bodies when evaluating their functioning in order to choose possible ways to implement certain measures to improve their ability to perform tasks as assigned.
Descriptions of three new Sonitha Zolotuhin & Prozorov, 2010 (Lepidoptera: Lasiocampidae: Lasiocampinae: Gastropachini) from West Africa in the collections of the African Natural History Research Trust, with taxonomic notes on the genus
Authors: Takano Hitoshi
Published: April 2024

Three new species of Sonitha Zolotuhin & Prozorov, 2010 are described from recently collected West African material housed in the African Natural History Research Trust: S. smithi sp. n., S. bryoniae sp. n. and S. laszloi sp. n. Taxonomic notes are provided for the hitherto poorly-delimited S. libera (Aurivillius, 1914) and S. chocolatina Zolotuhin & Prozorov, 2010 with clear specific boundaries established for the two taxa.
Rus Salnamelerine Göre Türkistan Askerî Valiliği’nde Nüfus Hareketleri (1867-1917)
Authors: Güngör Ebubekir
Published: April 2024

Rusların Türkistan’ı işgali ile 1867 yılında kurulan Türkistan Askerî Valiliği, 1882 yılına kadar sürekli genişlemiştir. 1899 yılında klasik sınırları şekillenen valilik, çar tarafından atanan askerî valiler aracılığı ile yönetilmiştir. Askerî Valilik yönetiminde bulunan nüfusu, coğrafi ve zamansal bütünlük temelinde resmî veriler üzerinden analiz etmeyi amaçlayan bu çalışmada Rus salnameleri temel kaynak olarak kullanılmış; SSCB döneminde ve sonrasında üretilen literatürden faydalanılmıştır. Valilik bölgesinde 19. yüzyıldan 20. yüzyıla geçişte gözlemlenen toplumsal hareketlilik ve yürütülen iskân politikası ile nüfusun şehirli-kırsal, kadın-erkek, yerleşik-göçerlik ve dinî özelliklerine göre gösterdiği değişimin bölgelere dağılım oranları ve değişim seyirleri değerlendirilmiştir. Buna göre Fergana ve Semerkant eyaletleri nüfusun yoğun olduğu ve göç alan bölgeler olarak dikkati çekmektedir. Yedisu ve Siriderya Askerî Eyaletleri ise en fazla gayrimüslim nüfusun iskân edildiği alanlardır. Nüfusun kırsal, konargöçer ve Müslüman karakteri ise şehirli, yerleşik ve gayrimüslim nitelikleri lehine olmak üzere eyaletlere göre farklı oranlarda değişim göstermiştir.
Spiritual Resources for Anger Management: Spirituality Integrated Cognitive Behavioral Group Therapy
Authors: Yılmaztürk Mücahit
Published: April 2024

This study aims to examine the effects of a group counseling program based on spirituality-integrated cognitive behavioral therapy on adolescents’ trait anger, anger control, external dysfunctional emotion regulation, and positive religious coping. The research used a quasi- experimental design with a pretest-posttest control group. Criterion sampling, which is one of the purposive sampling types, was used in the selection of the participants in the study. Participants who met the criteria determined within the scope of the study were ranked according to their scores. Then, odd-numbered ones were assigned to the control group, and even-numbered ones were assigned to the experimental group. While the mean age of the experimental group (n=10) comprising 6 female and 4 male participants was 16.1, the mean age of the control group (n=10) comprising 8 female and 2 male participants was 15.4. The psychological counseling program was applied to the experimental group with 8 sessions, each lasting 90 minutes. The trait Anger and Anger Style Scale, Religious Coping Scale, and Adolescent Emotion Regulation Scale were used as data collection tools. Mann-Whitney U Test and Wilcoxon Signed Rank Test were used in data analysis. As a result of the study, it was found that the cognitive behavioral therapy-based group spiritual counseling program significantly decreased adolescents’ trait anger and external dysfunctional emotion regulation skills, and significantly increased their anger control and positive religious coping levels. The findings were discussed within the literature framework and recommendations were presented.
Causalidade e causalismo em políticas públicas
Authors: Pinheiro Maurício Mota Saboya
Published: April 2024

O objetivo principal do artigo é avaliar criticamente o causalismo, definido como uma interpretação absolutizada e reducionista da causalidade aplicada a políticas públicas. O causalismo afirma que decisões de políticas públicas requerem conhecimento sobre relações causais e que as evidências científicas devem explicar as causas dos problemas sociais. Porém, não contempla, por exemplo, a possibilidade de as variáveis componentes de uma explicação causal serem definidas com certo grau de imprecisão, tampouco serem sujeitas a diferentes nuances interpretativas. O artigo defende que a análise de políticas públicas necessita de conceitos de causalidade mais sintonizados às realidades humanas complexas e construídas em processos onde imperam formas específicas de racionalidade e de incerteza. O artigo conclui que o causalismo é conceitualmente estreito e inadequado à realidade da pesquisa social e das políticas públicas, o que nos leva à necessidade de ampliar o foco conceitual da causalidade, das teorias causais, das narrativas e das explicações causais em políticas públicas.
A VECM Analysis on the Impact of Agricultural Exports, Financial Openness and Trade Openness on India's Ecological Footprint
Authors: Agarwal Teesha , P. Sreelakshmi
Published: April 2024

The 21st century has witnessed a surge in concerns surrounding environmental degradation, prompting investigations into its contributing factors. This study delves into the impact of agricultural exports and financial openness on the ecological footprint of India, utilizing time series data for a comprehensive analysis. Employing unit root tests and the VECM model for cointegration analysis, the study offers compelling insights. The findings reveal a positive association between agricultural exports and a reduction in India’s ecological footprint in both the long and short run, suggesting that increased agricultural exports contribute to environmental sustainability. The study demonstrates a positive association between financial openness and the ecological footprint, indicating that increasing financial openness leads to environmental sustainability in India. These findings align with previous studies highlighting the potential trade-offs between economic growth and environmental protection. Conversely, the study identifies trade openness is negatively associated with the Ecological Footprint, increase in trade openness leads to an increase in environmental degradation. Furthermore, the study identifies economic growth as an additional factor significantly impacting India’s ecological footprint. These findings underscore the complex interplay between various economic and environmental forces. This study contributes to the ongoing dialogue on sustainable development by providing valuable empirical evidence on the specific case of Ind. The findings offer policymakers crucial insights for crafting strategies that promote economic growth while minimizing environmental harm.
Mixed Algorithm of SINDy and HAVOK for Measure-Based Analysis of Power System with Inverter-based Resource
Authors: Saeed Kandezy Reza , Ning Jiang John
Published: April 2024

Artificial intelligence and machine learning is enhancing electric grids by offering data analysis tools that can be used to operate the power grid more reliably. However, the complex nonlinear dynamics, particularly when coupled with multi-scale interactions among Inverter-based renewable energy Resources, calls for effective algorithms for power system application. This paper presents affective novel algorithm to detect various nonlinear dynamics, which is built upon: the Sparse Identification of Nonlinear Dynamics method for nonlinear dynamics detection; and Hankel Alternative View of Koopman method for multi-scale decomposition. We show that, by an appropriate integration of the strengths of the two, the mixed algorithm not only can detect the nonlinearity, but also it distinguishes the nonlinearity caused by coupled Inverter-based resources from the more familiar ones caused synchronous generators. This shows that the proposal algorithm can be a promising application of artificial intelligence and machine learning for data measure-based analysis to support operation of power system with integrated renewables.
A Re-evaluation of Global Financial Outlooks and Prospects in the Telehealth Industry Amidst the Transition to a Post-Pandemic Era
Authors: K Arunkumar
Published: April 2024

The onset of the COVID-19 pandemic propelled the telehealth sector into a period of rapid expansion, with web-based care emerging as a crucial tool for ensuring the safety of patients and healthcare providers alike. However, with the introduction of vaccines, the perceived need for telehealth services appeared to diminish, leading to a decline in value for telehealth companies. This shift prompted both existing players and newcomers in the telehealth space to innovate and redefine their value propositions in order to regain investor and customer confidence and stand out amidst increasing competition. The struggle to reshape the perception of telehealth from a pandemic-era necessity to a valuable complement to traditional in-person care has been reflected in the volatility of stock prices and declining valuations. This dynamic has underscored the need for telehealth companies to differentiate themselves through technological advancements and the convenience they offer. Analyzing the market through qualitative secondary research, incorporating insights from contemporary sources, financial data from platforms like Yahoo! Finance, and peer-reviewed literature, it becomes evident that the telehealth market experienced a surge in 2020, reaching $17.9 billion in the US alone, and is projected to grow to $140.7 billion by 2030. This growth was accompanied by a nearly twofold increase in digital health venture funding, reaching $14.1 billion in total funding. However, this rapid expansion led to an oversaturation of the market, with supply outpacing demand, resulting in a significant drop in valuations as vaccination rates rose in 2021. In response to this rebalancing, telehealth companies must chart a course for the post-pandemic era. The current role of suppliers in the telehealth space, whether they are established healthcare industry incumbents or innovative "telehealth-first" challengers, will influence the growth strategies they pursue. Moreover, identifying medical specialties and patient demographics that are best suited for web-based care will be critical for long-term success in the evolving healthcare delivery system. Looking ahead, investors should anticipate a bullish market characterized by growing share prices. Success in the telehealth industry is likely to hinge on fundamentally transforming care delivery models rather than simply transitioning traditional care to a web-based format. As the market consolidates, established telehealth giants capable of adapting to the changing landscape are expected to thrive, albeit amidst continued growth at a slower pace.
SENTI Aid: Sentiment Analysis on Personal Relations and Aiding Mental Health
Authors: Kataria Aditya , Desai Riva , Kapadia Hassan , Patel Rohan , Maru Aashka , Shah Bhumika , Pandya Dhatri
Published: April 2024

This research examined the ability of a novel mobile application designed to provide proactive mental health support by analyzing the user’s conversations and recommends interventions accordingly. Employing sentiment analysis of the user's recorded discussions with designated social contacts (parents, siblings, partner), the application identifies indicators of potential issues in mental health. A personalized chatbot then interacts with the user, offering feedback based on the sentiment analysis and engages in positive conversation to uplift user’s mood. Additionally, the system monitors the user's application activities and chatbot interaction patterns, detecting atypical behaviors for further feedback or prompting emergency alerts to pre-defined contacts. The research employed a two-phased approach: an initial pilot study with simulated data to refine the sentiment analysis and chatbot algorithms, followed by a validation study with a limited user group, utilizing actual conversation recordings. Analysis of the pilot data showed promising accuracy in identifying negative sentiments, while the validation study demonstrated a significant improvement in positive engagement and self- reported well-being among participants. Overall, the findings suggest that this multi-faceted approach using sentiment analysis and conversational AI holds potential for early detection and proactive intervention in mental health issues, justifying further investigation and refinement for broader implementation.
Implant Guide X - An Extraoral Guide for Optimal Implant Placement in Orthodontics
Authors: S Navya , Saba Khan Iram , Sabrish Sharanya , S Bhat Sagar , B C Amarnath , C S Prashanth
Published: April 2024

Orthodontic mini-screws provide absolute skeletal anchorage and can be placed in various sites according to needs. The advantage of these implants is their ease of insertion and removal, as well as the ability to immediately withstand forces. Placing mini-screws too close to the root surface can result in insufficient bone remodeling due to occlusal forces transmitted through the teeth to the implant, leading to implant failure. The conventional method of placing interradicular implants often led to incorrect positioning, causing perforation of the dental root and subsequent loss of vitality, osteosclerosis, and dentoalveolar ankylosis. To address these issues, numerous intra-oral implant placement guides have been developed. In our study, we developed a prototype of an extra-oral detachable metal mesh grid that can be attached to the parallelogram x-ray positioner (RIN XCP). This prototype promises increased accuracy and utility in implant placement.
Analysis of Biometric Authentication Techniques: A Review
Authors: kumar Vivek , Rao K Nageshwara
Published: April 2024

This report delves into diverse biometric authentication techniques and offers an overview of their evolution, applications, limitations, advancements, and comparative attributes. It also highlights biometric authentication's pivotal role in elevating security and convenience across sectors.
Dietary exposure to aflatoxin B1 and ethanol from homemade and industrial fermented beverages in South Kivu, Democratic Republic of the Congo
Authors: Mahano Aladin Ombeni , Agamy Neveen Fahmy , Mohamed Doaa Tawfik , Bekhit Salma Adnan , El Tawila Mahmoud Mohamed
Published: April 2024

BACKGROUND: The prevalence of AFB1 contamination in agricultural products used to produce fermented alcoholic beverages is increasing, raising concerns for human health.
AIM: The aim of this study was to investigate dietary exposure to AFB1 and ethanol through homemade and industrial fermented beverages commonly consumed in South Kivu, DR Congo.
METHOD: AFB1 and ethanol were measured using reverse-phase HPLC with a fluorescence detector and a refractive index detector, respectively. Data on fermented beverage consumption were collected from 847 adults using a food frequency questionnaire (FFQ).
RESULTS: The findings revealed that industrial sample Man 8 had the highest exposure to AFB1 (77.8 ± 45.0 ng/kg b.w/day) and Man4 had the highest ethanol exposure (4.83 ± 2.40 mg/kg b.w/day); while among homemade samples, Kasiksi had the highest exposure to both AFB1 (8.8 ± 6.6 ng/kg b.w/day) and ethanol (2.46 ± 1.85 mg/kg b.w/day). The margin of exposure (MOE) for AFB1 was 1011.7 or less, and for ethanol, it was 818.2 or less. Men are more likely to be exposed.
CONCLUSION: Increased consumption of homemade and industrial fermented beverages raises the risk of developing hepatocellular cancer (HCC) because the levels of AFB1 and ethanol MOE drop below the safe limit of 10000. Further research is needed to investigate the connection between AFB1, ethanol, and HCC, especially in regions where alcohol misuse is common.
The role of cellular polyploidy in the regeneration of the cirrhotic liver in rats and humans
Authors: Bezborodkina Natalia N. , Brodsky Vsevolod Ya. , Kudryavtsev Boris N.
Published: April 2024

Polyploidy is a condition in which a cell has multiple diploid sets of chromosomes. Two forms of polyploidy are known. One of them, generative polyploidy, is characteristic of all cells of the organism, while the other form develops only in some somatic tissues at certain stages of postnatal ontogenesis. Whole genome duplication has played a particularly important role in the evolution of plants and animals, while the role of cellular (somatic) polyploidy in organisms remains largely unclear. In this work we investigated the contribution of cellular polyploidy to the normal and the reparative liver growth of Rattus norvegicus (Berkenhout, 1769) and Homo sapiens Linnaeus, 1758. It is shown that polyploidy makes a significant contribution to the increase of the liver mass both in the course of normal postnatal development and during pathological process.
Les opportunités manquées de Kodak dans les technologies de l’imagerie numérique : une analyse fondée sur la défaillance des choix stratégiques
Authors: Le Guern Nicolas
Published: April 2024

En 2012, la société Kodak se plaçait sous la loi américaine sur la faillite, ne pouvant faire face à ses pertes suite à la disparition progressive de la photographie argentique depuis le tournant des années 2000. On explique fréquemment cet échec industriel par le fait que Kodak, faisant face à une technologie de rupture, fut confronté à un véritable dilemme et ne sut pas négocier le virage vers les technologies de l’imagerie numérique. Notre article pondère cette théorie en la considérant trop réductrice. Ses processus d’innovation bien structurés permirent à Kodak d’étudier les technologies des capteurs CCD et de concevoir la première caméra numérique magnétique dès les années 1970. Si le groupe américain se diversifia trop dans l’industrie chimique, cela ne l’empêcha pas de développer progressivement une R&D (Recherche & Développement) dans le numérique, et d’introduire sur le marché des produits soit hybrides argentiques-numériques, soit entièrement numériques.
Android-based Mobile Application for Door-to-Door Product Delivery
Authors: Atawneh Samer , Al-Kasasbeh Basil , Ben Rshed Mohammed
Published: April 2024

Many companies, such as Aramex, FedEx, and SMSA, offer product delivery services. However, the delivery process through these companies is costly and/or requires the customer’s physical attendance at the company to get the sent shipments. There is a persistent need to improve the delivery process in Saudi Arabia to reduce the effort, cost, and time that the customer spends to get the shipped products. This paper presents a new delivery approach in Saudi Arabia by developing an Android-based MobApp that allows the customers to use their mobile devices to send and receive shipped products at their doorstep by submitting online requests through the developed MobApp. The proposed MobApp, named as Door-to-Door (D2D) product delivery MobApp, guarantees fast and costless service among its competitors. The MobApp will provide its customers a reliable delivery process. It aims to provide a domestic delivery chain with whomever to wherever within Saudi Arabia. In addition, the proposed delivery MobApp allows the customers to create, update and track the delivery orders. Moreover, the proposed D2D delivery MobApp is easy to install and use, it provides a friendly GUI and has a powerful steady performance.
« Deconstructing the Map 2.0 » : réflexions sur une mise en pratique
Authors: Andermann Jens
Published: April 2024

Publié à la fin des années 1980, l’essai du géographe et historien de la cartographie John Brian Harley, qu’évoque le titre de cet essai, nous a introduit à une approche poststructuraliste de la critique des cartes. Mobilisant une instrumentalité derridienne, Harley insistait sur une réimagination des cartes comme palimpsestes denses de gestes rhétoriques qui tissent un réseau complexe de pouvoir sur les pratiques spatiales qu’elles induisent. Ceux d’entre nous qui, au cours des décennies suivantes, ont appris à « déconstruire » les cartes comme des trames de conquête, de colonialité et de pouvoirs étatiques et para-étatiques, plutôt que comme de simples « représentations » d’espaces préexistants, ont commencé en même temps à explorer par la pratique pédagogique les multiples possibilités de « hacking » participatif offertes aujourd’hui par l’omniprésence des cartes numériques. Dans cet essai, je me demande si la possibilité inédite d’intervenir dans le dispositif cartographique peut nous offrir des opportunités pour une critique nouvelle et différente, un « déconstruire la carte 2.0 ». Après avoir rappelé rapidement ma propre expérience d’analyse « déconstructive » des cartes, je conclurai en présentant quelques usages concrets que l’on pourrait donner à la cartographie comme outil de production participative de connaissances1.
Cartographier l’Argentine dans les années 1860 : les cartes à texte de Victor Martin de Moussy
Authors: Larrue Christophe
Published: April 2024

L’ouvrage du Français Victor Martin de Moussy, Description géographique et statistique de la Confédération argentine, financé par le gouvernement argentin, comprend trois tomes descriptifs, publiés à Paris entre 1860 et 1864 et qui sont complétés par un atlas, publié en 1869. Cette œuvre monumentale peut être vue comme une carte de présentation du pays au monde extérieur, notamment lors de l’Exposition universelle de Paris de 1867, et affiche sa volonté de contribuer à attirer des colons européens.L’article se propose d’analyser quelques choix de représentation effectués par V. Martin de Moussy (avec des traits de la géographie physique, humaine, économique mais aussi son inclusion d’une dimension temporelle) ainsi que les textes inscrits dans les cartes elles-mêmes. En effet, si les légendes sont succinctes, l’espace de la carte est assez bavard, porteur de précisions sur la végétation, l’hydrographie ou la sécurité, énoncées par de véritables phrases. Les choix linguistiques (graphies, multilinguisme et traduction) effectués par l’auteur, retiendront particulièrement notre attention, pour en interroger les réalités qu’ils signalent et la manière de les signaler.
Mapa, territorio y literatura. Vicente Blasco Ibáñez y Argentina y sus grandezas (1910)
Authors: Catala Alexandre Bataller
Published: April 2024

La obra del escritor valenciano Vicente Blasco Ibáñez (1867-1928) es propicia a su transformación en mapas literarios con el objeto de visibilizar los lugares de sus novelas. Su vida puede ser también leída de forma cartográfica, como muestra su itinerario literario y viajero alrededor del mundo. Blasco Ibáñez viajó por primera vez al continente americano en 1909, donde recorrió los países de Argentina, Uruguay, Paraguay y Chile dictando más de ciento veinte conferencias. A su regreso a España, en enero de 1910, inició la escritura de Argentina y sus grandezas, un libro de encargo, entre la enciclopedia y el cuaderno de viaje, homenaje al Centenario de la Independencia de la República Argentina (25.5.1910). El libro incluye la litografía de un mapa a color de la República Argentina, reproducciones de mapas de los siglos xvi y xvii, y muestra una redacción basada en los mapas. Los mapas son usados con una intención ideológica, propagandística y nacionalista de una República Argentina en expansión que incorpora la Patagonia y olvida a la población indígena. El éxito de la obra motivó a Blasco su decisión de colonizar dos territorios argentinos periféricos, Cervantes y Nueva Valencia (1910-1914). Conocedor de las obras geográficas y seguidor de los hermanos Reclus, sus acciones y su obra literaria muestran la importancia, para el acceso al conocimiento, del acceso personal al territorio por encima de los mapas descontextualizados de la realidad.
L’étain « des cours d’eau »
Authors: Tomczyk Céline
Published: April 2024

Si se procurer de l’étain était d’une importance majeure à l’âge du Bronze, la manière dont ce dernier était extrait est mal connue. À l’heure actuelle l’existence de seulement une trentaine de mines d’étain est supposée en Europe et les exploitations alluvionnaires en constituent les deux-tiers. Cependant, ces structures peu marquées dans les paysages et facilement détruites par des phases de reprises postérieures sont complexes à identifier. L’étain alluvionnaire n’était pas nécessairement plus facile à exploiter que les mines en roche car il demandait de très bonnes connaissances des réseaux hydrographiques pour y établir des chantiers. Ainsi, si l’étain alluvionnaire constituait certainement une ressource précieuse, l’importance des mines en roche ne doit pas être sous-estimée.
Pêcher devant sa porte ?
Authors: Danger Maxime
Published: April 2024

L’ichtyofaune issue des occupations lacustres de Serteya II datées du IIIe millénaire avant J.-C. constitue un ensemble de plus de 20 000 restes osseux de poissons. Les principales espèces ciblées par les pratiques de pêche sont le brochet, les Cyprinidés (brème, carassin, gardon, rotengle et tanche) et les Percidés (perche et sandre). Des dispositifs piégeants, comme des filets et des nasses, servent à leur capture. Ces poissons sont pêchés principalement durant le printemps, lors de leurs périodes de reproduction, et surtout dans les eaux qui bordent les rivages des habitats néolithiques. Ces prises sont ensuite écaillées et éviscérées dans des fosses dédiées et leurs restes de consommations rejetés dans des zones préférentielles autour des constructions d’habitat.
Le transport des matériaux de construction centro-italiques en terre cuite à l’époque romaine
Authors: Ploux Victor
Published: April 2024

De la fin de la République romaine jusqu’au vie siècle après J.-C., des matériaux de construction originaires des figlinae d’Italie centrale se diffusent à travers le territoire romain. Ces matériaux ont dû emprunter la Méditerranée et plusieurs fleuves pour arriver à destination, comme en témoignent la présence d’épaves à cargaison de tuiles en Méditerranée et la localisation des découvertes le long des côtes et des rivières. La plupart du temps, ces matériaux auraient servi de chargement complémentaire, ou de chargement de retour d’Italie. Dans d’autres cas, ils auraient été le résultat de commandes spécifiques, comme en Afrique du Nord ou en Sardaigne. La diffusion de ces objets est un témoin des routes fluvio-maritimes empruntées à l’époque entre l’Italie et les provinces extérieures.
Hydrosystèmes anthropiques de la Montagne de Reims
Authors: Berthe Julien , Ancelin Pierre-Yves
Published: April 2024

La Montagne de Reims, située entre Épernay et Reims, correspond à la terminaison orientale des plateaux tertiaires de la cuesta d’Île-de-France. Ce plateau forestier est drapé d’Argiles à Meulières qui entretiennent des milieux humides. Le traitement d’un MNT LiDAR à haute résolution révèle des formes naturelles et des vestiges archéologiques dont 650 km de fossés et des ouvrages hydrauliques. Ils sont connectés au réseau hydrographique et au karst constituant des hydrosystèmes complexes. Le croisement des données LiDAR avec les documents d’archive et la palynologie permet de proposer un phasage du forçage humain (pisciculture, enchâtellement et drainage) sur les écoulements de la zone d’étude.
Traditions et renouvellements dans l’approche des anciens systèmes d’irrigation de l’Asie centrale
Authors: Cez Lucie
Published: April 2024

Les expéditions soviétiques ont étudié les anciens systèmes d’irrigation de l’Asie centrale selon une démarche innovante d’archéologie du paysage, de la photo-interprétation jusqu’à la fouille des vestiges hydrauliques. Sous la doxa des valeurs matérielles des modes de production, l’histoire du perfectionnement des techniques d’irrigation produite dans une perspective évolutionniste dit peu de choses des contraintes et des pratiques de gestion de l’eau liées à la fonctionnalité des réseaux. À Sarazm, en rive gauche du Zeravchan, notre étude géoarchéologique documente les caractéristiques d’un canal de haute terrasse du début de l’âge du Bronze. L’étude micromorphologique de son comblement révèle les modalités de fonctionnement et de maintenance de l’ouvrage dans un contexte sismique.
Des ponts, des chapelles et des saints
Authors: Lazaro Aude
Published: April 2024

À la fin du xve siècle, alors que le déperchement de l’habitat s’amorce pour de nombreux villages et à la faveur d’une reprise économique après la « grande dépression médiévale », le réseau viaire se redessine et investit les fonds de vallée. Au débouché des ponts qui permettaient de franchir les cours d’eau parfois capricieux de ces vallées encaissées du sud-ouest des Alpes viennent s’implanter de petits lieux de culte. La polarisation par les ponts de chapelles, mais aussi la « sacralisation » de certains ponts, notamment par le remplacement du toponyme d’origine au profit de l’hagiotoponyme (toponyme évoquant un saint, un édifice religieux ou encore une relique) du lieu de culte révèlent l’irruption du sacré dans le réseau hydrographique et viaire, afin de conjurer le danger des fleuves et rivières : les saints avaient en effet la charge de protéger celles et ceux qui franchissaient le cours d’eau, à l’instar du pont, mais aussi de protéger le pont lui-même.
Gouvernance des villes et Union européenne : La dimension urbaine de la politique de cohésion sous le prisme de la géographie
Authors: Sénécat Chloé
Published: April 2024

Sans en avoir la compétence, celle-ci étant réservée aux Etats, les institutions européennes mettent en place une politique en direction des villes. Souvent étudiée au prisme de la science politique et de ses concepts comme celui de la gouvernance multi-niveaux, le recours à la géographie politique est nécessaire pour analyser une politique territorialisée. L’article, en s’appuyant sur une revue de la littérature, explicite cette approche. Géographie et science politique sont complémentaires pour étudier la corrélation entre gouvernance et territorialité, dans le cadre de la dimension urbaine de la politique de cohésion. En étudiant de manière spatialisée les instruments utilisés par la Commission européenne, l’approche géographique doit permettre de réinterroger la notion de gouvernance multi-niveaux par l’analyse de jeux d’échelles entre les acteurs ou encore de souligner l’instrumentalisation d’un discours par la Commission européenne, afin de passer outre son absence de compétence dans l’urbain.
Ce que les comportements sur le terrain nous disent des chercheurs : une expérimentation réflexive menée en Cévennes
Authors: Errero Fabienne , Cerceau Juliette , Ayral Pierre-Alain , Lachassagne Patrick , Gramaglia Christelle
Published: April 2024

La crise écologique bouscule les savoirs scientifiques établis, elle requiert à ce titre une plus grande réflexivité de la part des chercheurs pour ce qui est de leur rapport distancié au terrain. La question se pose de savoir comment favoriser une interconnexion qui leur permettrait de se rendre attentif aux singularités des territoires. Souhaitant contribuer à ce mouvement, nous avons organisé une « sortie de terrain » avec des hydrologues pour analyser leur posture et leurs pratiques. Nos résultats montrent que, s’il existe plusieurs rapports au terrain, ceux-ci ne sont jamais tout à fait dénués d’engagement sensible, corporel et esthétique, quand bien même ces engagements sont habituellement tus. Nous questionnons les postures épistémiques des chercheurs embarqués dans notre expérimentation et discutons des possibilités nouvelles qui s’offrent pour le dialogue interdisciplinaire.
Quelle gouvernance pour un numérique sobre ?
Authors: Deruelle Valérie , Metzger Jean-Luc
Published: April 2024

Face à l’impératif de réduire les empreintes des activités humaines, les incitations à pratiquer la sobriété se multiplient, notamment dans le secteur du numérique. Pourtant, en appeler, de façon indiscriminée, à la sobriété individuelle se révèle inapproprié – les usages individuels ne représentant qu’une faible part des empreintes –, ignore l’inégale distribution des responsabilités en matière d’empreintes, néglige l’importance des impacts sociétaux du numérique, et risque d’aggraver les inégalités ou d’en créer de nouvelles. Pour réduire durablement les empreintes du numérique, nous suggérons que la gouvernance du système sociotechnique soit assurée par la délibération entre des pouvoirs publics soucieux de réguler les acteurs du marché, des collectifs altruistes de citoyens, soucieux de définir leurs propres besoins, et les entreprises du numérique dans lesquelles les citoyens et les travailleurs auraient le même poids décisionnel que les actionnaires.