bluuebunny/crossref_metadata_2025 huggingface dataset:
Vignettes cliniques
Authors: Depaigne-Loth Anne , Rullon Isabelle , Mounic Vincent
Published: November 2024

Une « vignette clinique » est une histoire clinique courte donnant lieu à des questions qui permettent de mettre en situation un professionnel de santé et d’évaluer ce qu’il ferait s’il était confronté à un cas similaire. Issues de la tradition de la casuistique en médecine, les vignettes cliniques constituent un moyen pour exercer ses compétences et pour évaluer ses pratiques. Simple d’apparence, cet outil d’apprentissage et d’amélioration est puissant, mobilisant des mécanismes cognitifs sophistiqués et capables de reproduire les processus d’analyse et de décision tels qu’ils sont sollicités dans les situations cliniques réelles. En 2020, les vignettes cliniques ont été reconnues comme une méthode pertinente de développement professionnel continu (DPC) par la Haute Autorité de santé. Cette reconnaissance dans le cadre du DPC français est l’occasion de faire le point sur les connaissances sur cette méthode d’apprentissage et d’évaluation des pratiques professionnelles en santé. Cet article présente les résultats saillants de la revue de littérature établie à l’occasion de l’inclusion de la méthode « vignettes cliniques » dans la liste des méthodes de DPC.
« Qu’est-ce qui est important pour vous ? » Amorcer le partenariat avec le patient et ses proches
Authors: Staines Anthony , Coelho Veronica , Gutnick Damara Nadine , Mattelet Audrey , Louiset Mathieu
Published: November 2024

Les soins centrés sur le patient répondent à ses préférences, besoins et valeurs. Encore faut-il connaître ces derniers. C’est dans ce but que le concept « Qu’est-ce qui est important pour vous ? » a été développé. L’idée de considérer le patient comme une personne globale et de s’intéresser à lui au-delà de ses symptômes et de sa pathologie a rapidement séduit, débouchant sur une campagne internationale dès 2014, qui a gagné la francophonie en 2019. Ce concept promeut un échange visant à comprendre le point de vue du patient sur sa santé, à découvrir ses circonstances de vie, ses priorités et ses valeurs. La relation de confiance et d’empathie ainsi créée permet de construire avec lui un traitement et un plan de soins qui prennent en compte ses objectifs et auquel il adhère. Tout professionnel de santé peut conduire une telle conversation, puis en consigner les éléments clés dans la documentation clinique à disposition de l’équipe pluriprofessionnelle. Il s’agit d’abord de demander ce qui est important, de pratiquer une écoute active, puis de reformuler ce qui semble être l’essentiel en demandant sa validation à l’intéressé. Il convient alors de prendre en compte ce qu’a exprimé le patient pour la suite des soins afin de développer un partenariat avec lui. La méthode invite le professionnel à mettre de côté les objectifs qu’il attribue au patient, et à cesser d’imaginer savoir ce qui compte pour lui.
Blumer, la légende
Authors: Lacaze Lionel
Published: November 2024

Utilisation du contre-transfert et de la réflexivité pour reconstruire les bases de la recherche en psychologie sociale de l’auteur à travers le football et l’interaction symbolique comme éléments d’une auto-analyse et d’un savoir incarné.
Les nœuds et les liens de la société contemporaine chez Michel Maffesoli : pensée, vent et souffle
Authors: De Lemos Martins Moisés
Published: November 2024

Mon propos est de présenter quelques idées fortes de la pensée de Michel Maffesoli, le sociologue qui a choisi la pensée d’une largesse et d’une liberté sans restriction, une pensée qui est l’apanage d’une véritable Universitas , en opposition à la « langue de bois » de la pensée unique, qui se contente de clichés, de stéréotypes, de dogmatismes, de théories de convenance et du jargon institué. Et, d’autre part, j’aimerais mettre en avant la façon dont ce sociologue a valorisé les possibilités de l’humain, contre l’horizon obscur d’une société logocentrique, phallocrate et prométhéenne, une société qui reste dupe dans les finalités qu’elle poursuit.
Observation de l’action publique et stage doctoral
Authors: Charrier Dominique , Lopez Clément , Djaballah Mathieu
Published: November 2024

Cet article s’appuie sur un travail doctoral en sciences et techniques des activités physiques et sportives (STAPS), portant sur l’articulation entre les politiques sportives locales et les stratégies des fédérations sportives. Il questionne les leviers d’observation d’un objet singulier – l’action publique sportive – dans des conditions spécifiques : la réalisation d’une thèse financée par un contrat doctoral universitaire. La contribution présente certaines techniques d’enquête mobilisées pour contourner les difficultés d’accès aux organisations politiques et sportives (animation de conférences, participation à des commissions, diffusion de la recherche dans des espaces professionnels, etc.). Elle revient en partie sur la conception d’une innovation méthodologique intitulée « stage doctoral », qui a permis au doctorant de se positionner en immersion au sein d’une collectivité locale. L’article discute ces différents positionnements en démontrant que le statut de doctorant contractuel peut, lorsqu’il est mobilisé stratégiquement par le chercheur, générer des opportunités méthodologiques pour observer l’action publique sportive en train de se faire.
Pseudo-Stieltjes calculus: $ \alpha- $pseudo-differentiability, the pseudo-Stieltjes integrability and applications
Authors: Wang Caiqin , Xie Hongbin , Gong Zengtai
Published: November 2024

In this paper, the concepts of the $ \alpha- $pseudo-differentiability and the pseudo-Stieltjes integrability are proposed, and the corresponding transformation theorems and Newton–Leibniz formula are established. The obtained results provide a framework for analyzing nonlinear differential equations.
Za zidovi
Authors: M. Heins Volker , Wolff Frank , Troha Tadej
Published: November 2024

At a time when the external borders of Europe and the entire West are being reinforced more than ever, and the inhabitants of the Global South are being reduced to less than nothing, any theoretical intervention that disrupts this hardened consensus is especially welcome. Heins and Wolff, on the one hand, provide a wealth of empirical material — particularly valuable are their insights into the (para-)agency Frontex — and, on the other, return to fundamental reflections on the effects of enclosure on the internal dynamics of society. A society that closes itself off is, of course, no longer open; however, this does not necessarily mean it is simply closed, tyrannical, and restrictive. The transformation produced by obsessive enclosure from the outside is much more complex, far more elusive, and, in the long run, significantly more dangerous. Some may believe they know what awaits us at the end of this path. But if the process continues in the direction in which political and fabricated popular consensus wishes to push us, the final destination will be so foreign and inhospitable that we, too, will wish to flee.
Gestión consorciada de LibQUAL en las bibliotecas de la Red BUCOC, Argentina
Authors: Martin Sandra Gisela , Lago Soledad
Published: November 2024

Se presenta la experiencia de cooperación en la gestión consorciada de LibQUAL para la evaluación de la calidad de la Red de Bibliotecas de Universidades Católicas y de Orientación Católica (Red BUCOC) de Argentina. Se buscó realizar un diagnóstico de las bibliotecas, utilizando una metodología común para relevar y analizar las necesidades de los usuarios y así diseñar un plan estratégico que mejore y aporte calidad a los servicios de la red. Se presentan, además, las dificultades y los beneficios de la aplicación de encuesta LibQUAL. Los resultados dan cuenta que el control de la información es la dimensión menos valorada y que el valor afectivo del servicio es la mejor reconocida. Se concluye que lo más requerido por los usuarios hoy son los espacios y servicios. Si bien la colección no es el servicio más requerido, es la dimensión donde las bibliotecas deberán enfocar su análisis junto a los usuarios para determinar su desarrollo y entorno de acceso.
The Science of Human Skin
Authors: Thanawiroon Charuwan , Khumsikiew Jeerisuda , Yingngam Krit
Published: November 2024

The appearance and health of the skin, the body's largest organ, significantly influence an individual's perceived attractiveness. It appears healthy when it glows and seems aged when it turns rough and becomes susceptible to diseases. For this reason, comprehension of the science behind human skin is the way to create cosmeceuticals that bridge the gap between cosmetics and pharmaceuticals. This chapter aims to provide all the details of the skin's anatomy, its cellular composition by layers, its important processes, and the main external stimuli with which the skin, as a barrier, interacts. The chapter also discusses recent dermatology findings and innovative technologies that have aided in the advancement of cosmeceuticals. To summarize, the above are the key elements of this chapter on the anatomy, physiology, and biological function of the skin.
Exploring Bioactive Ingredients in Natural Cosmeceuticals
Authors: Van Tran Chen , Vo Tu Linh , Tran Quynh Thi Thuy , Nguyen Triet Thanh
Published: November 2024

Since early times, plant-based products and their isolated phytocompounds have been used in cosmeceutical fields to improve appearance, health, and aging. In recent years, the cosmeceutical field has focused mainly on the combination of cosmetics and pharmaceuticals, which has increasingly required thorough research because of the need for scientific evidence of novel bioactive cosmeceutical ingredients. In fact, the development of active ingredients in natural cosmeceuticals and the demonstration of their safe and effective products in this field have gained significance. A new product with good bioavailability and guaranteed stability is a requirement of the cosmeceutical industry when new formulas are designed. The exploration of natural cosmeceutical ingredients, such as polysaccharides, peptides, flavonoids, phenolics, alkaloids, fatty acids, vitamins, and other compounds, is interesting in the cosmeceutical field. In this chapter, novel bioactive phytocompounds applied in natural cosmeceuticals are described together with scientific evidence.
A Comprehensive Analysis of Plant-Derived Compounds
Authors: Upadhyay Pushkar
Published: November 2024

The growing demand is driving the growth of the herbal cosmetics industry globally and attracting the attention of nature to priceless gifts. Herbal skin care products are created by combining a variety of herbal active ingredients with a cosmetic base to nourish and cure certain skin conditions. As the main component of sunlight, ultraviolet radiation is crucial for causing skin damage. They cause a variety of skin conditions, such as rashes, sunburn, erythema, and skin cancer. Since ancient times, natural substances have been used in traditional medicines as well as in healing practices across numerous cultures. They have been used in topical creams, lotions, and preparations. Clinical and laboratory studies conducted over the last 20 years have revealed the advantages of a variety of natural substances for skin care. The morphological and physiological characteristics of the skin are constantly changing. It has been shown that bioactive substances such as polyphenols strengthen the endogenous antioxidant system of the skin, preventing a number of skin issues.
The Evolution of Data CSR Disclosure From Web 1.0 to Web 2.0
Authors: Keserwani Hitesh , Rastogi Himanshu , Chandra Ashish , Bhadauria Arun , Pramanik Sabyasachi
Published: November 2024

This chapter examines how technological advancements have affected corporate social responsibility (CSR) disclosure. It examines how the use of new technologies is influencing the evolving requirements of various stakeholders for CSR disclosure and the mutually reinforcing relationships among them. For businesses and society at large, it is imperative to comprehend the enormous implications that technology will have on corporate social responsibility (CSR) disclosure as it advances. From the pre-Internet era to Web 2.0, the growth of Internet technology has had a profound influence on how companies interact with stakeholders. This chapter will undertake a critical analysis of how technology has changed the disclosure of corporate social responsibility (CSR) and how these developments have influenced stakeholder engagement. This chapter also provides answers for relevant issues in the social media era.
AI-Powered Insights Revolutionizing Pharmacy Operations
Authors: Jain Aishwarya
Published: November 2024

The integration of digital technologies in healthcare is transforming pharmacy practices. This chapter explores the impact of AI-driven analytics, mobile technology, telemedicine, and personalized diabetic platforms on pharmacy services, highlighting benefits and challenges. It examines how mobile technology and IoT devices streamline medication management and enhance patient adherence. Emerging technologies like AR/VR/MR augment patient education and adherence. Lessons from COVID-19 emphasize the importance of digital health strategies and telemedicine for continuity of care. The chapter also explores 5G's role in advancing real-time communication, smartphones for early cancer detection, and intelligent decision support systems for diabetic patients. It underscores care coordination and the reliability of wireless body area networks for health monitoring. This analysis offers insights into the evolving digital health landscape, informing practitioners and stakeholders about the opportunities and challenges of these technologies.
Bridging Academia and Industry
Authors: Syed Ayesha , Subbarayudu Y.
Published: November 2024

University-based business incubators are essential catalysts for innovation, bridging the gap between academic research and industry needs. This chapter examines the evolution, structure, and function of these incubators, emphasizing their role in fostering entrepreneurship and driving economic growth. Through collaborative partnerships between academia, industry, and startups, university-based incubators facilitate the commercialization of research findings and the development of innovative products and services. Success stories of startups emerging from these incubators highlight the tangible impact of mentorship, resources, and strategic partnerships. Despite challenges such as funding constraints and bureaucratic hurdles, university-based incubators continue to adapt and thrive, advancing the innovation ecosystem. By providing a supportive environment for entrepreneurial ventures and promoting interdisciplinary collaboration, these incubators play a vital role in shaping the future of innovation and entrepreneurship.
Achieving Bankability and Business Success Among Female Entrepreneurs
Authors: Noor Nurul Hidayana Mohd , Omar Noralina , Zaini Syeliya Md , Beta Raja Mayang Delima Mohd
Published: November 2024

Economic growth promotes entrepreneurial activity that provides job opportunities, reduces unemployment and social problems, and improves the standard of living. This positive contribution can also reduce dependence on imported goods. Business incubators have proven to be effective in accelerating the growth of new businesses. This chapter aims to investigate and identify the factors of business incubators as a catalyst to facilitate female entrepreneurs' success and bankability. This study adapted the survey method using a questionnaire as a research instrument. This study examines 180 samples through structural equation modeling (SEM). Testing the structured model shows business incubator training has significant relationships with bankability and business success. On the other hand, networking significantly influences business success and does not affect bankability. This study is expected to contribute to generating ideas, programs, and entrepreneurial activities to increase the effectiveness of female entrepreneurship.
Impaired platelet function in Hermansky-Pudlak syndrome associated with novel mutations in HPS3, HPS6 and HPS8 genes
Authors: Pieri Lisa , Linari Silvia , Salvianti Francesca , Attanasio Monica , Castaman Giancarlo
Published: November 2024

We report three unrelated cases of Hermansky-Pudlak (HP) characterized by novel mutations in HPS3 (compound heterozygosity for c.1457G>A and c.1813G>T), HPS6 (homozygous c.210_211insGGGCC), and HPS8 (homozygous c.299dupC in BLOC1S3) genes. No spontaneous bleeding tendency was observed despite the presence of several platelet function abnormalities. Screening test with PFA-100 failed to detect the abnormality. This report confirms the pattern of poor bleeding risk in patients with rare HP and the need for detailed platelet function studies despite normal hemostatic screening tests.
Vitamin D and intrauterine growth restriction: a cross-sectional study
Authors: Arnan Fadhilah , Chalid Maisuri T. , Farid Monika Fitria , Lukas Efendi , Wewengkang Ellen
Published: November 2024

Vitamin D plays a critical role in maintaining bone health, regulating calcium homeostasis, and modulating immune responses. During pregnancy, it supports fetal bone mineralization and proper placental function. Deficiency in vitamin D can impair calcium absorption, disrupt placental function, and lead to adverse outcomes like intrauterine growth restriction (IUGR). Despite abundant sunlight, vitamin D deficiency is highly prevalent in countries like Indonesia. This study evaluates the relationship between maternal vitamin D levels and IUGR risk while considering additional factors like placental function and calcium metabolism. In this cross-sectional study, 60 patients, 30 with IUGR and 30 without, were included. Vitamin D levels were measured using the enzyme-linked immunosorbent assay, and statistical analysis compared the IUGR and non-IUGR groups. Baseline data [age, body mass index (BMI), placental inflammation, preeclampsia status] were analyzed using Chi-square and Mann-Whitney tests. Statistical significance was set at p<0.05, using IBM SPSS 24 (IL, USA). A significant association between maternal factors and IUGR was found. Higher BMI (≥25 kg/m2) and placental inflammation were more prevalent in the IUGR group. Vitamin D deficiency was strongly linked to IUGR, with 90% of IUGR cases showing deficient levels. The IUGR group had significantly lower vitamin D levels (13.84 ng/mL versus 25.93 ng/mL), with a strong inverse correlation (r=-0.86, p=0.00). This study shows a strong link between maternal vitamin D deficiency and increased IUGR risk, emphasizing its role in placental function and fetal development.
Prosthodontic Rehabilitation of Mucormycosis Patient Following Hemimaxillectomy with an Obturator and Orbital Prosthesis
Authors: Nair Athira K. , Vijayaraghavan Vasantha , Mundhe Darshana , Sabane Ajay
Published: November 2024

Mucormycosis is a severe fungal infection that can cause significant damage to the maxillofacial tissue, requiring complex rehabilitation techniques. The interdisciplinary team comprising maxillofacial surgeons, prosthodontists, and oculoplastic surgeons devised a tailored approach to address the patient’s functional and esthetic concerns. The obturator was meticulously fabricated to restore oral competence, facilitate speech articulation, and prevent nasal regurgitation. Concurrently, the orbital prosthesis aimed at restoring facial symmetry and concealing the enucleated eye, thereby improving the patient’s psychological well-being. This case report presents the collaborative efforts of various specialties in the successful fabrication of both an obturator and an orbital prosthesis for a patient with mucormycosis-induced maxillofacial defects.
Tissue Invasive Bacteria in Periodontitis Patients – A Preliminary Case Control Study
Authors: Victor Dhayanand John , Anandan Nirmala , Venkadassalapathy Santosh
Published: November 2024

Introduction:

The ability for bacteria that make up the dental biofilm to invade the gingival epithelium and connective tissue has been a feature of many bacteria, including those that are seen to be periodontopathic. This mechanism is primarily understood as a survival strategy of bacteria to evade host defense mechanisms and to survive during the varied ecological stresses faced by bacteria that make up the dental biofilm. This strategy of tissue-invasive bacteria immediately brings a much wider zone of activity for these tissue-invasive organisms, due to their potential to interact with the varied cells and receptors of the immune system, as they traverse the gingiva. This study was performed to address a definite lacuna that exists in the understanding of tissue-invasive bacteria and periodontitis.

Materials and Methods:

This study sought to quantitate the total extent of tissue-invasive bacteria in tissue samples that were procured from patients undergoing modified Widman flap surgery for the management of periodontal defects among patients who were diagnosed to be affected by Stage III and Grade C periodontitis, with patient sites that could be designated as healthy, mild to moderate, and severe, that would need to be included to provide the appropriate surgical access. A total of 10 such patients were recruited and taken up for surgery, and the tissue samples so procured were taken up for analysis of total tissue-invasive bacterial phylotypes within the samples procured by quantitative polymerase chain reaction.

Results:

All the tissue samples evaluated had tissue-invasive bacterial phylotypes that were evidenced from sites that were designated as severe, mild to moderate as well as healthy. The mean copy numbers in 157.20 ± 122.37/μl in the healthy sites, 232.50 ± 133.064/μl in the mild-to-moderate sites, and 340.70 ± 177.18/μl in the severe sites. On statistical evaluation of this difference in the copy numbers between the three groups, a statistically significant difference was found on comparison of the tissue invasive bacteria between the healthy and severe sites. (P < 0.024).

Conclusions:

This study highlights that all sites in patients who are designated as Stage III and Grade C periodontitis harbor tissue-invasive bacteria, notwithstanding whether they had experienced clinical attachment loss earlier. There are statistically significant differences in the levels of tissue-invasive phylotypes when comparing the healthy sites with those with severe destruction. Tissue-invasive bacteria is probably a significant factor to be considered in the management of periodontitis.
Los retos de la integración de las TICs en los procesos educativos. Límites y posibilidades
Authors: Cabero Almenara Julio
Published: November 2024

Las Tecnologías de la Información y Comunicación (TIC) se están convirtiendo en una de las variables críticas de los entornos formativos de la Sociedad del Conocimiento, ofreciéndonos diferentes tipos de posibilidades: ampliación de la oferta informativa, creación de entornos más flexibles para el aprendizaje, eliminación de las barreras espacio-temporales entre el profesor y los estudiantes, incremento de las modalidades comunicativas, potenciación de la interacción social entre los participantes, las que son analizadas en el artículo. Aunque también presentan una serie de limitaciones: acceso y recursos necesarios por parte del estudiante, necesidad de una infraestructura administrativa específica, costo para la adquisición de equipos con calidades necesarias para desarrollar una propuesta formativa rápida y adecuada; que deben ser contempladas para su correcta incorporación a la práctica educativa. Se finaliza con algunas de las medidas que pueden servir para ello: aumentar su presencia física hasta alcanzar la invisibilidad, existencia de centros dinamizadores, transformación de las concepciones que tenemos sobre la enseñanza y del papel que en la misma juegan las TIC, formación del profesorado, cambio del currículo, superar las incertidumbre que todo cambio provoca, alfabetización informática-mediática, transformar las estructuras organizativas, y potenciación de la investigación educativa.
Incidencia de los estilos de aprendizaje, estrategias de aprendizaje y la autoestima, en el logro académico de estudiantes universitarios de alta vulnerabilidad: Estudio de Caso en la Universidad de Concepción-Chile
Authors: Solar María Inés , Domínguez A. Lucía , Sánchez H. José
Published: November 2024

El artículo aborda los problemas generados por la masificación de la Educación Superior en Chile, en especial en la Universidad de Concepción. A pesar de las dificultades que presentan los estudiantes vulnerables, hay jóvenes que logran superarlas y terminan con éxito sus estudios. La investigación se orienta a conocer el perfil de estos estudiantes y la incidencia de los estilos, estrategias de aprendizaje y la autoestima en el logro académico. Se eligió la metodología cualitativa y cuantitativa que permite abarcar una perspectiva mixta por etapas. La población corresponde a estudiantes que ingresaron el año 2008 a diferentes carreras, que no han reprobado ninguna asignatura y han obtenido un promedio sobre nota 5 (escala de 1 a 7) y que pertenecen a los dos primeros quintiles. Los resultados evidencian que la Autoestima Escolar, muy alta se relaciona con el Procesamiento Profundo y el Procesamiento Elaborado de la información. La Autoestima Social se relaciona con el Estilo Pragmático, en su categoría alta y muy alta. La Autoestima general se relaciona con el Estilo Activo. La influencia de estas variables en el éxito académico, posibilitarán generar interacciones y desarrollar acciones en los procesos de enseñanza-aprendizaje, en estudiantes de similares condiciones de vulnerabilidad.
The Community Interest in the Cape Town Convention
Authors: Nelson Jack Wright
Published: November 2024

The Cape Town Convention is viewed as a private law convention, with one of its principal objectives being to insulate creditors’ and lessors’ interests in aircraft objects from the often-turbulent finances that characterize the international civil aviation industry. This article promotes a different perspective. I argue that the Cape Town Convention reflects what international legal theory calls a ‘community interest’ – specifically, the community interest in the creation of global markets. This argument is motivated by a desire to better integrate the Cape Town Convention in international law, as a means of restoring confidence in the Convention in the aftermath of Russia’s effective nationalization of non-Russian aircraft – an event popularly known as ‘Grand Theft Aero’.
КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ БЕРЕМЕННОЙ ПАЦИЕНТКИ С МИОМОЙ ШЕЙКИ МАТКИ
Authors: С.Н. Буянова , Н.В. Зароченцева , И.В. Баринова , И.В. Краснопольская , О.В. Трищенкова
Published: November 2024

Миома шейки матки – редко встречающаяся патология, которая обнаруживается во время беременности менее чем у 1% женщин. Все больше пациенток откладывают материнство на более поздний репродуктивный срок, в связи с чем возрастает риск возникновения миом, в том числе во время беременности. На сегодняшний день нет утвержденного алгоритма ведения беременности и родов у женщин с миомой шейки матки, что затрудняет наблюдение пациенток данной группы. В статье представлено клиническое наблюдение беременной пациентки с миомой шейки матки: ведение беременности, родов, а также послеродовое лечение.

Cervical fibroids are a rare pathology and are detected during pregnancy in less than 1% of women. More and more patients are postponing motherhood until later in their reproductive years, and therefore the risk of fibroids becomes higher, including during pregnancy. To date, there is no approved method of managing pregnancy and childbirth in women with cervical fibroids, which makes it difficult to monitor this group of patients. The article presents a clinical observation of a pregnant patient with cervical fibroids: management of pregnancy, childbirth, and postpartum treatment.
ЭКСЦИЗИОННЫЕ МЕТОДЫ ЛЕЧЕНИЯ ПЛОСКОКЛЕТОЧНЫХ ИНТРАЭПИТЕЛИАЛЬНЫХ ПОРАЖЕНИЙ ШЕЙКИ МАТКИ ВЫСОКОЙ СТЕПЕНИ (ОБЗОР ЛИТЕРАТУРЫ)
Authors: И.В. Кардава , Н.В. Зароченцева , А.Р. Фаттахов , О.В. Трищенкова
Published: November 2024

В статье представлен обзор научной литературы, в которой рассматриваются эксцизионные методы лечения плоскоклеточных интраэпителиальных поражений шейки матки высокой степени (high-grade squamous intraepithelial lesions, HSIL) у пациенток разных возрастных категорий. Технологическое развитие в последние десятилетия привело к созданию новых методик, однако классические процедуры лечения HSIL остаются по-прежнему актуальными.

The article presents a review of the scientific literature, which discusses excisional methods of treatment of high-grade squamous intraepithelial lesions (HSIL) of the cervix in patients of different age categories. Technological developments over the past decade have led to the creation of new techniques, but the classic treatments for HSIL remain relevant.
On the name of Messambria Pontica
Authors:   Institute of Balkan Studies and Centre of Thracology  “Prof. Alexander Fol” Bulgarian, Academy of Sciences, Sofia, Topalilov Ivo
Published: November 2024

The present text deals with the etymology of the name of one of the Western Pontic colonies, Messambria Pontica. Although it has been a topic of discussion since antiquity, the problem is still not considered resolved, with debates continuing among modern scholars. Many questions remain unanswered, such as whether the name is a single word or a compound, whether it is of Greek or Thracian origin, or whether it is composed of a combination of two Thracian glosses, two Greek glosses, or a mixture of Thracian and Greek elements. In fact, the etymology of the name sheds light on the earliest period of the colony’s history, which in turn raises additional challenges for scholars to address.
Castrul de marș de la Rânca
Authors:   Muzeul Național de Istorie a României, Țentea Ovidiu , Călina Vlad ,   Muzeul Național de Istorie a României
Published: November 2024

A temporary camp has been reported in the Parâng Mountains. It is located in Gorj County, UAT Novaci. Its dimensions are similar to other temporary camps found in the alpine areas, i.e. 5 ha. Two gates with tituli have been identified. Its location brings back into question a new route that the Romans used to attack the Dacian capital.
‘Llamá a las mujeres de MOCASE': respuestas feministas campesinas y populares frente a las violencias hacia mujeres de la ruralidad y de las periferias urbanas en Argentina
Authors: Pena Mariela
Published: November 2024

Este artículo indaga en el problema del abordaje de las violencias de género desde estrategias organizacionales de base, a partir del caso de mujeres campesinas del Movimiento Campesino de Santiago del Estero-Vía Campesina (MOCASE-VC), del norte de Argentina. Se describe y analiza el accionar del “equipo de género” conformado por algunas mujeres de la organización de manera voluntaria entre los años 2020 y 2024, el cual se ocupa de recibir, atender y gestionar pedidos de asistencia por parte de mujeres jóvenes y adultas de zonas rurales y peri-urbanas de Santiago del Estero, en distintas situaciones de vulnerabilidad y/o emergencias que son caratuladas como “violencia de género”. Los datos que se comparten y analizan forman parte de un trabajo investigativo más amplio (2016-actualidad) basado en un abordaje etnográfico y feminista que combina técnicas de trabajo de campo como entrevistas, observaciones participantes y conversaciones informales. Se plantea la relevancia de enmarcar esta experiencia en la trayectoria de los feminismos campesinos y populares, su perspectiva interseccional del género y la construcción de nuevas subjetividades. Se argumenta que éstos aportan una concepción crítica, integral y ampliatoria sobre la noción de “violencia” respecto de los feminismos hegemónicos y de las políticas públicas existentes durante dicho período. El caso de estudio también arroja nuevos interrogantes en torno a la relevancia del Estado, de los feminismos y de las organizaciones sociales a la hora de atender estas problemáticas.
Об индексе бисингулярного оператора с инволютивным сдвигом
Authors: С.В. Ефимов
Published: November 2024

В теории сингулярных операторов с инволютивным сдвигом полностью изучены вопросы н{\"е}теровости (фредгольмовости) и индекса оператора вида $A+VB$, где $A$ и $B$~--- сингулярные операторы, а $V$~--- оператор инволютивного сдвига в пространстве $p$-суммируемых функций на простом замкнутом контуре типа Ляпунова. Вместе с оператором $A+VB$ рассматривается соответствующий матричный сингулярный оператор без сдвига $M=\left(\begin{array}{cc}A&{VBV}\\B&{VAV}\end{array}\right)$. Хорошо известно, что операторы $A+VB$ и $M$ н{\"е}теровы или нет одновременно, а их индексы относятся как 1:2. Аналогичные вопросы об одновременной н{\"е}теровости и пропорциональности индексов возникают для бисингулярных операторов с инволютивным сдвигом $A+WB$ и их соответствующих матричных операторов $M=\left(\begin{array}{cc}A&{WBW}\\B&{WAW}\end{array}\right)$, где $A$ и $B$~--- бисингулярные операторы, а $W$~--- оператор инволютивного сдвига в пространстве $p$-суммируемых функций на прямом произведении простых замкнутых контуров типа Ляпунова. В настоящей работе исследованы бисингулярные операторы с инволютивным сдвигом, распадающимся на одномерные компоненты. Рассмотрены два вида таких сдвигов~--- покоординатный и перекрестный. В этих случаях соответствующие матричные операторы являются матричными бисингулярными операторами без сдвига. Получена одновременная н{\"е}теровость бисингулярного оператора со сдвигом и соответствующего матричного бисингулярного оператора без сдвига. Установлена пропорциональность индексов бисингулярных операторов с покоординатным сдвигом и соответствующих матричных операторов, а именно: доказано, что индексы этих операторов относятся как 1:2. В частном случае такой же результат об индексах получен и для перекрестного сдвига.
PERFORMANCE OF MEDICAL WASTE ASH AS A PAVING BLOCK: IMPACTS TO AIR QUALITY AND HEAVY METALS IN PRODUCT
Authors:   Universitas Diponegoro, Universitas Sebelas Maret, RACHMAWATI SITI , SYAFRUDIN SYAFRUDIN ,   Universitas Diponegoro, BUDIYONO BUDIYONO ,   Universitas Diponegoro, FITRI SITI NURLITA ,   Universitas Sebelas Maret
Published: November 2024

In compliance with regulation of the Republic of Indonesia 22 of 2021, hazardous and toxic waste (B3) producers are obligated to use B3 waste. The purpose of this research is to assess the influence of using ash from incinerated medical waste on air quality and to identify the concentration of heavy metals in paving block products such that its use is ecologically and environmentally benign. Air quality is measured as dust present in it using the Gravimetry technique while noise was measured using a Sound Level Meter. The Toxicity Characteristic Leaching Procedure (TCLP) was used to determine the level of lead Pb, nickel (Ni), copper (Cu), and cadmium (Cd) compounds in the product. The usage of medical waste ash had an influence on the environment with respect to air quality in the form of dust with a value that exceeds the prescribed quality standard threshold, but noise values on the environment and health can be tolerated. Ash from the burning of medical waste has the potential to be used as paving blocks with a soaking period of between seven
and 14 days, with metal levels of Ni, Cu, and Cd well below the quality limits imposed by the government. Unlike the heavy metal compound Pb, above the TCLP B (0.5 mg/l). Medical waste ash has the potential to be used as paving blocks with the addition of a pozzolanic composition so that it can bind the maximum amount to heavy metals.
CAPÍTULO 3 Estadificación TNM
Authors: Amarillo Hugo
Published: November 2024

CAPÍTULO 3
Estadificación TNM
CAPÍTULO 15 Terapia adyuvante
Authors: Amarillo Hugo
Published: November 2024

CAPÍTULO 15
Terapia adyuvante
PESCATARIAN DIET MIGHT BE MORE BENEFICIAL IN TERMS OF MAINTAINING DNA INTEGRITY
Authors:   Institute for Medical Research and Occupational Health, Division of Toxicology, Zagreb, Croatia, Gajski Goran , Matkovic Katarina ,   Institute for Medical Research and Occupational Health, Division of Toxicology, Zagreb, Croatia, Kazensky Luka ,   Institute for Medical Research and Occupational Health, Division of Toxicology, Zagreb, Croatia, Gerić Marko ,   Institute for Medical Research and Occupational Health, Division of Toxicology, Zagreb, Croatia
Published: November 2024

Certain lifestyle factors such as physical activity and diet can affect a variety of health-related biomarkers and also impact the stability of DNA through the upregulation of the antioxidant defence system and alteration of its repair capacity. Besides, there is growing evidence suggesting that plant-based diets, as well as preferential consumption of fish and seafood, may promote health, longevity, and well-being. Hence, here we aimed to investigate the impact of different dietary preferences on the primary DNA damage in young healthy females residing in Zagreb (Croatia). The participants were divided into vegetarians and non-vegetarians, with the non-vegetarians further classified as either omnivores or pescatarians. The results showed significantly higher DNA damage in vegetarians compared to non-vegetarians, with the lowest DNA damage observed in pescatarians. Our results indicate that the pescatarian diet could be more beneficial in terms of maintaining DNA integrity and warrants further research in this particular area.
FILTERS DEVELOPMENT FOR THE PURIFICATION OF INDUSTRIAL WATER OF CLAY MINERALS
Authors:   Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia - University of Belgrade, Kokunešoski Maja , Ružić Jovana ,   Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia - University of Belgrade
Published: November 2024

In this study, clay from the Kolubara mine in Serbia was used to make filters as a separation media. This study, as a consequence, explores the scientific area of developing porous materials from natural minerals and areas of environmental protection. After clay purification, H3BO3 contents of 2 wt.% and 0.5 wt.% were used as a low-cost, environmentally friendly chemical to create a porous structure. The influence of different amounts of H3BO3 on the separation ability of the clay filter was monitored. Additionally, various synthesis conditions, such as low pressing pressure of up to 60 MPa and low sintering temperatures of 1150 oC and 1300 oC were applied to prepare the filter medium with good separation and mechanical properties, such as good strength and Young’s modulus.
UV/VIS DETERMINING TARTRAZINE (E 102) IN A COMMERCIAL FOOD DYE
Authors:   University of Belgrade, Institute of General and Physical Chemistry, Studentski trg 12-15, 11000 Belgrade, Republic of Serbia, Sencanski Jelena , Maksimović Jelena ,   University of Belgrade, Faculty of Physical Chemistry, Studentski trg 12-15, 11000 Belgrade, Republic of Serbia, Pastor Ferenc ,   University of Belgrade, Faculty of Chemistry, Studentski trg 12-15, 11000 Belgrade, Republic of Serbia, Bajuk-Bogdanovic Danica ,   University of Belgrade, Faculty of Physical Chemistry, Studentski trg 12-15, 11000 Belgrade, Republic of Serbia, Stevanovic Kristina ,   University of Belgrade, Institute Vinča, Mike Alasa, 11000 Belgrade, Serbia Republic of Serbia, Simovic Pavlovic Marina ,   University of Belgrade, Photonics Center, Institute of Physics, University of Belgrade, Pregrevica 118, 11000 Belgrade, Serbia, Perać Sanja ,   University of Belgrade, Institute for Multidisciplinary Research, Kneza Višeslava 1, 11030 Belgrade, Republic of Serbia, Pagnacco Maja C. ,   University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Njegoševa 12, 11000 Belgrade, Serbia
Published: November 2024

Our research presents an analytical curve applicable to accurately determining unknown concentrations of tartrazine in an aqueous solution of any sample. The analytical curve that this study develops may be used to determine the concentration of tartrazine in an aqueous solution of a typical commercially available food dye, which is a mixture of tartrazine and dextrose. The concentration determined in the sample of the food dye was c=7.76 g/ dm3. The examined food dye contained 0.27% of tartrazine. To characterize the presented analytical method, LOD (limit of detection) and LOQ (limit of quantification) were then calculated, obtaining better values compared to the data existent in the literature.
ALPHA AND BETA ACTIVITY IN HERBAL TEA LEAVES
Authors:   Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, 11351 Belgrade, Serbia, Stanic Vojislav , Sarap Nataša ,   Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, 11351 Belgrade, Serbia, Jelic Ivana V. ,   Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, 11351 Belgrade, Serbia, Jankovic Marija ,   Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, 11351 Belgrade, Serbia, Jovanović Dragoljub ,   Faculty of Veterinary Medicine, University of Belgrade, 11000 Belgrade, Serbia, Gavrilovic Ljubica ,   Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, 11351 Belgrade, Serbia, Stojiljković Vesna ,   Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, 11351 Belgrade, Serbia
Published: November 2024

Seven herbal teas used in Serbia were analyzed to determine gross alpha and beta natural radioactivity. In all samples, the gross alpha in herbal teas ranged from 149 Bq/kg in the Melissa leaf sample to 193 Bq/kg in the Bilberry Leaf. The gross beta in herbal teas ranged from 272 Bq/kg in the Bilberry Leaf sample to 1091 ± 117 Bq/kg in the Burdock leaf sample.
EFFICIENT CHLORPYRIFOS REMOVAL FROM WATER USING CELLULOSE-DERIVED POROUS CARBONS
Authors:   VINCA Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovica Alasa 12–14, 11000 Belgrade, Serbia, Tasić Tamara , Milanković Vedran ,   VINCA Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovica Alasa 12–14, 11000 Belgrade, Serbia, Unterweger Christoph ,   Wood K Plus—Kompetenzzentrum Holz GmbH, Altenberger Strasse 69, 4040 Linz, Austria, Fuerst Christian ,   Wood K Plus—Kompetenzzentrum Holz GmbH, Altenberger Strasse 69, 4040 Linz, Austria, Breitenbach Stefan ,   Wood K Plus—Kompetenzzentrum Holz GmbH, Altenberger Strasse 69, 4040 Linz, Austria, Pasti Igor ,   Faculty of Physical Chemistry, University of Belgrade, Studentski Trg 12–16, 11158 Belgrade, Serbia, Lazarevic-Pasti Tamara ,   VINCA Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovica Alasa 12–14, 11000 Belgrade, Serbia
Published: November 2024

The widespread use of the organophosphate pesticide chlorpyrifos, coupled with its acute neurotoxicity, underscores the urgent need for effective remediation strategies. Among the various methods explored for chlorpyrifos removal from water, adsorption has emerged as the most promising. We investigated the potential of two cellulose-derived porous carbons, produced via different activation strategies, as adsorbents for chlorpyrifos removal from water. The kinetics of batch adsorption fit well with both pseudo-first-order and pseudo-second-order models for both materials. Additionally, the Freundlich and Langmuir isotherm models accurately described the adsorption process in all cases studied. The maximum adsorption capacities, determined from the Langmuir model, were 3.8×106 mg g−1 and 1.3×106 mg g−1. Comparative analysis with existing literature validates these findings, highlighting the efficacy and potential of cellulose-based porous carbons for sustainable chlorpyrifos remediation.
Gentiana lutea ROOT EXTRACT CYTOTOXIC CONCENTRATION ACTIVATES APOPTOSIS IN PERIPHERAL BLOOD MONONUCLEAR CELLS
Authors:   VINČA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Republic of Serbia, Valenta Šobot Ana , Drakulic Dunja ,   VINČA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Republic of Serbia, Katnic Djurica ,   VINČA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Republic of Serbia, Butulija Svetlana ,   VINČA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Republic of Serbia, Janić Marijana ,   VINČA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Republic of Serbia, Krstić Aleksandar ,   VINČA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Republic of Serbia, Filipovic Trickovic Jelena ,   VINČA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, Republic of Serbia
Published: November 2024

Gentiana lutea root extract displays protective effects, including activity against oxidative stress, inflammation, and effects on the cardiovascular and central nervous systems. Plant-derived compounds could protect against disease progression by regulating homeostasis and eliminating damaged cells, acting like pro-apoptotic agents. In this work, we aimed to test the impact of cytotoxic concentrations of Gentiana lutea root extract on the activation of apoptosis, a controlled cell death mechanism, in peripheral blood mononuclear cells. Apoptotic DNA degradation was tested by a fragmentation assay. Immunoblot was used to detect proteins Bcl2, Bax, cleaved PARP1, and caspase3 as markers of apoptosis. We detected a high level of DNA fragmentation, an elevation of the Bax, cleaved caspase3, and PARP1 fragments that are indicators of cell death by apoptosis. Gentiana lutea root extract cytotoxic concentration eliminated cells with limited response to xenobiotic exposure by apoptosis.
ELECTROCHEMICAL DETERMINATION OF CARBARYL IN FRUIT JUICE USING AgNPs@rGO MODIFIED ELECTRODE
Authors:   Chemnitz University of Technology, Measurement and Sensor Technology, 09126 Chemnitz, Germany, Weheabby Saddam , Wang C. ,   Chemnitz University of Technology, Measurement and Sensor Technology, 09126 Chemnitz, Germany, Kanoun Olfa ,   Chemnitz University of Technology, Measurement and Sensor Technology, 09126 Chemnitz, Germany
Published: November 2024

In this study, we developed an electrochemical sensor using silver nanoparticles (AgNPs) incorporated onto reduced graphene oxide (rGO) modified screen-printed carbon electrodes (SPCE) for the detection and quantification of carbaryl in grape juice. The proposed sensors demonstrated a detection limit (LoD) of 0.061 µM within a concentration range of 0.1 to 50 µM. When applied to real samples, the sensors exhibited satisfactory recovery rates, highlighting their potential for practical applications in food safety and environmental monitoring.