bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospects of the 21st Century Skills in Education: an implication for Competency Based Curriculum in Kenya
Authors: Ajuoga Milcah Aoko , Odhiambo Ongunya Rafael
Published: December 2023

Education in the 21st-Century seems to have surpassed mere learning of the stipulated curriculum areas. In the information technology era, young people are already faced with the challenges of social media interactions as well as other networks that call for certain mannerisms for acceptability. Settling well on the job as well as exhibiting certain competencies are some of the demands from the job market. It is, therefore, not a matter of just knowing what the work demands but building synergies from diverse team work is imperative. Developments in society and economy in this century, therefore, call for education systems that may equip young people with new skills and competencies, which allow them to benefit from the emerging forms of socialisation and to contribute actively to economic development under a system where the main asset is knowledge. This paradigm shift in the need for skills and competencies for young people to effectively respond to the demands of the emerging models of economic and social development unlike those in the past century which were suited to an industrial mode of production is imperative. This paper therefore reviewed literature in order to come up with novel ideas which may include the 21st-century competencies such as creativity, critical thinking, problem solving, ability to articulate, interpret and share thoughts and ideas.
Edukasi Pencegahan Diare pada Anak Sekolah Dasar Negeri 12 Kota Kendari
Authors: Irma Irma , Lestari Hariati , Gunawan Edi , AF Swaidatul
Published: December 2023

Menurut World Health Organization (WHO) diare adalah penyakit kedua yang menyebabkan kematian pada anak-anak setelah pneumonia, terutama pada negara – negara berkembang. Indonesia merupakan salah satu negara berkembang yang memiliki masalah penyakit menular. Kegiatan pengabdian ini berbentuk edukasi kesehatan yang bertujuan untuk memberi pengetahuan kepada anak usia sekolah dasar tentang  pencegahan penyakit diare. Hasil ini kegiatan ini menunjukkan bahwa pengatahuan anak sekolah dasar tentang pencegahan diare sebelum pelaksanaaan vidio edukasi atau penyuluhan singkat tergolong rendah yaitu dengan skor 54,0 dan setelah pemberian vidio edukasi dan penyuluhan singkat rata – rata pengetahuan tresponden menjadi baik yaitu dengan skor 79,33. Hasil uji statistik dengan uji Wilcoxan menunjukkan bahwa nilai p=0,000< α =0,05. Dengan demikian dapat dikatatakan bahwa pemberian vidio edukasi dan penyuluhan singkat berpengaruh terhadap tingkat pengatahuan siswa tentang pencegahan diare. Kegiatan pengabdian ini dapat dikatakan berhasil.
Pelatihan Penulisan Naskah Podcast Dalam Upaya Peningkatan Keterampilan Membuat Naskah Podcast Kepada Remaja
Authors: Afriyanto Dzul Fahmi
Published: December 2023

Podcast salah satunya yang bisa dijadikan sebagai media untuk memberikan informasi atau pengetahuan dengan tujuan pendidikan serta pemberdayaan masyarakat. Podcast sangat berkaitan dengan penulisan naskah, mengingat salah satu tahapan awal yang paling utama dalam memproduksi Podcast adalah menulis naskah. Maka dari itu, diperlukan adanya pelatihan penulisan naskah podcast terutama remaja di Gerakan Pemuda Peduli Kesehatan Kota Surakarta (GEMPITA) yang masih banyak belum mengetahui cara dan tahapan dalam pembuatan naskah podcast media kesehatan. Kegiatan ini termasuk pengabdian Masyarakat yang berkerja sama dengan pihak Gerakan Pemuda Peduli Kesehatan Kota Surakarta (GEMPITA). Peserta dihadiri 16 jumlah peserta yang dilakukan serentak pada satu ruangan. Kegiatan ini dilakukan di Universitas Kusuma Husada Surakarta. Kegiatan ini berisikan dengan penyampaian materi dan tanya jawab terkait pembuatan naskah podcast media kesehatan, dan praktik pembuatan naskah podcast. Partisipasi dan kesungguhan Remaja GEMPITA dalam mengikuti pelatihan dapat dikatakan baik. Hal ini terlihat dari keaktifan, kesungguhan dan antusiasme para Remaja GEMPITA melalui banyaknya pertanyaan yang diajukan ketika pelatihan berlangsung dan hasil naskah podcast yang bagus.
Penerapan Media Pembelajaran Dengan Aplikasi Ideal Dictionary Di SDN Megaluh
Authors: Sa'adah Lailatus
Published: December 2023

In the era of increasingly developing technology, almost all subjects use internet media. The android-based English Learning Application is a learning medium that is used interactively in understanding vocabulary that is easy for students to understand. The intended subject of this activity is a grade IV student of SDN Megaluh. The problem experienced by grade IV students of SDN Megaluh is that they do not get English lessons from the first to third grades due to the independent curriculum which results in them not getting English language learning. The purpose of creating this learning media is to make it easier for students to get to know some basic vocabulary in English. The methods used in this case are twofold, namely the lecture method and the question and answer method. Both of these methods are used to find out the needs of students. From the analysis with these two methods, an ideal dictionary application was created where this application will support learning. It is hoped that this application can later be developed again by SDN Megaluh to support English learning, especially for students who are still new to English lessons. Because this kind of application if developed in the future becomes a learning medium that is quite interesting for students.
Penyuluhan Kesehatan Tentang Pencegahan HIV dan AIDS
Authors: Sutanta Sutanta , Hasbi Habid Al , Rismawati Rismawati
Published: December 2023

Perubahan besar dalam pergaulan remaja masa kini disebabkan oleh kemudahan berkomunikasi melalui media sosial yang berkembang sangat pesat. Kenakalan juga dapat menimbulkan permasalahan dalam keluarga, masyarakat dan lingkungan kerja, jika anak terlibat dalam kenakalan maka akan berdampak pada prestasi pendidikan dan akademik anak. Rendahnya tingkat pendidikan dalam keluarga menyebabkan remaja mudah terpengaruh pergaulan bebas. Jenjang pendidikan terpenting di sana adalah pendidikan agama. Orang tua yang tidak melakukan pengawasan secara ketat menyebabkan remaja terjerumus ke dalam perangkap tanpa mengetahui apakah hal tersebut benar atau tidak.

Akibat pergaulan bebas adalah kebebasan dari seks bebas dan HIV-AIDS Penyakit HIV adalah penyakit yang sangat berbahaya, karena penyakit ini sangat berbahaya bagi kesehatan kita terutama bagi generasi penerus bangsa.

Penyakit HIV-AIDS selain seks bebas pada usia remaja dapat merusak diri sendiri berimbas kepada tatanan kehidupan keluarga, lingkungan masyarakat dan lingkungan sekolahnya, bahkan langsung atau tidak langsung merupakan ancaman bagi kelangsungan pembangunan serta masa depan bangsa dan negara kita tercinta. Kalangan remaja dan anak-anak yang berstatus sebagai pelajar membutuhkan penyuluhan mengenai bahaya seks bebas dan penggunaan narkoba mengingat pada dasarnya bahwa remaja tersebut mempunyai rasa keingintauan yang tinggi dan selalu ingin mencoba-coba hal-hal baru yang didapatkan dari informasi tersebut dan apabila hal ini tidak dibarengi dengan adanya pengawasan, bimbingan dan arahan dari berbagai pihak.

Pengabdian masyarakat ini dilakukan pada hari Kamis, 15 Juni 2023 jam 09.00 – 11.00 wib di Masjid MTS Negeri Semarang. Kegiatan ini dihadiri 70 peserta yaitu kelas 8. Kegiatan dikoordinir oleh ketua tim pengabdian dengan dibantu oleh kepala sekolah dan staf kantor. Adapun kegiatan dalam pengabdian masyarakat ini berupa penyuluhan tentang bahaya pergaulan bebas dan seks bebas. Setelah diberikan penyuluhan tentang bahaya pergaulan bebas dan seks bebas, siswa yang hadir sebanyak 32 siswa mampu menjawab pertanyaan tentang bahaya bahaya pergaulan bebas dan seks bebas.
Tuberculosis in Superficial Lymphadenopathy Based on Fine Needle Aspiration Cytology: A Cross Sectional Study
Authors: Nadeem Islam  , Mehreen Babar  , Aleena Rana  , Shirin Aamir  , Jahangir Anjum  , Muhammad Shahid Khan
Published: December 2023

Objective: To investigate the prevalence of tuberculosis among individuals presenting with superficial lymphadenopathy using Fine Needle Aspiration Cytology (FNAC) as a diagnostic method.
Methodology: This cross-sectional research spanned three years, conducted at HBS General Hospital in Islamabad from July 2016 to June 2019. The study enrolled individuals meeting specified inclusion and exclusion criteria, presenting with superficial lymph node enlargement. All participants provided written consent before undergoing fine needle aspiration cytology (FNAC), and the diagnosis of tuberculosis relied on histopathological findings.
Results: Among 632 patients aged 15 to 60 years who underwent FNAC following clinical examination and relevant lab investigations, 85.4% (n=540) exhibited cervical lymphadenopathy. Among these, 57.7% (n=312) were diagnosed with tuberculous lymphadenitis, comprising 58.3% females (n=182) and 41.6% males (n=130). Axillary lymphadenopathy was observed in 5.53% (n=35) of patients, among whom 3.64% females (n=23) and 2.1% males (n=13) were diagnosed with tuberculous lymphadenopathy. Generalized lymphadenopathy was seen in 5.1% (n=32) of cases, with 0.94% males (n=6) and 0.79% (n=5) demonstrating histological evidence of TB on FNAC. Inguinal lymphadenopathy was observed in 3.95% (n=25) of patients, including 0.94% males (n=5) and 0.47% females (n=3).
Conclusion: Lymphadenopathy, a prevalent clinical condition, encompasses various underlying causes, ranging from manageable tuberculosis to malignant conditions. FNAC serves as a safe and rapid diagnostic technique, reducing the need for excisional biopsies. In this study, cervical lymph nodes were most frequently affected by tuberculous lymphadenopathy, particularly among females.
Valoração de ativos públicos para concessão: o caso do aeroporto estadual de Ribeirão Preto
Authors: Lavor Rodrigo Felix , Montoro Stela Basso , Conceição Elimar Veloso , Santos David Ferreira Lopes
Published: December 2023

Para o êxito da política pública de concessão de serviços à iniciativa privada é fundamental a valoração do serviço público a ser concedido, visto a necessidade de equilibrar a viabilidade econômica deste empreendimento com o princípio da economicidade ao erário público. A literatura financeira apresenta modelos consolidados para avaliação econômica, sob o pressuposto da maximização da riqueza, contudo, há poucas evidências empíricas da aplicação desses modelos em condições de concessões públicas, onde o valor econômico da concessão deve convergir as necessidades dos entes público e privado; especialmente, quando há elevada incerteza nas fontes de receita do serviço, como é o caso de aeroportos.  Nesta lacuna teórico-empírica, este estudo tem como objetivo analisar a viabilidade econômica do Aeroporto Estadual de Ribeirão Preto - Doutor Leite Lopes para concessão à iniciativa privada. O método empregado combinou o Fluxo de Caixa Descontado com a Simulação de Monte Carlo para identificar o valor de equilíbrio, considerando 1.000 cenários e controlar a incerteza da demanda. Todas as premissas para a elaboração do Fluxo de Caixa foram detalhadas e estruturadas com dados primários e secundários para 30 anos de concessão. A taxa de desconto foi estimada pelo método de precificação de ativos de capital.  O resultado do estudo apontou que o equilíbrio entre a viabilidade e a economicidade foi de R$ 84 milhões para o valor de outorga, reportando uma taxa interna de retorno média anual de 9,43% e o payback descontado no décimo oitavo ano de concessão. Ao demonstrar esse processo de valoração, esta pesquisa pode: i) auxiliar formuladores de políticas públicas e profissionais de mercado que assessoram ou elaboram projetos de investimento; ii) ampliar a discussão quanto ao valor “justo” de um serviço público e; iii) servir de parâmetro para outros casos similares.
Ações de investimento em CT&I para a facilitação de parcerias entre instituições brasileiras no período de pandemia
Authors: Nascimento Jose Vanderson Cunha , Lefevre Fernanda Sá Freire , Serique Hudson Aguiar , Silva Shirley Lins , Borba Marcelo da Costa
Published: December 2023

Este artigo teve por objetivo analisar as ações de investimento no país em ciência, tecnologia e inovação no período de pandemia, sob a ótica da facilitação de parcerias. Sendo utilizado como base teórica o modelo de Hélice Tríplice sobre inovação que valoriza as parcerias entre universidades/ICT-empresas-governo. A metodologia utilizada focalizou na coleta de dados em instituições que tradicionalmente fomentam a interação Universidade/ICT-empresa e de aplicação de recursos. Também, foi realizada uma pesquisa de opinião através de questionário eletrônico, a fim de avaliar o papel emergencial de enfrentamento ao coronavírus. Os resultados dessa pesquisa corroboraram para a identificação de ações de mobilização de pessoas e de instituições governamentais, acadêmicas e empresariais. Permitindo o impulsionamento da Hélice Tríplice e o engajamento em ações de enfrentamento e em projetos com parcerias. Por outro lado, fatores como a alta burocracia e a falta de investimento as atividades em ciência, tecnologia e inovação impedem o desenvolvimento do sistema de nacional de inovação.
CFD modeling of flow and local scour around submerged bridge decks
Authors: Fleit Gábor , Baranya Sándor , Ehlers Ronja , Bihs Hans
Published: December 2023

In this study, the level set method-based, multiphase hydro- and morphodynamic numerical model REEF3D is used for the simulation of the flow conditions and local scouring around submerged bridge decks. Presence of hydraulic jumps, bridge overtopping, pressurized jets and the resulting scouring make the selected test cases especially challenging from the numerical modelling point of view. The models are validated against data from laboratory experiments. The influence of the submergence ratio on the prevailing flow and scouring is investigated. The level set method showed robustness and good accuracy for the treatment of the complex free surface as well as for the tracking of the mobile bed. The submergence ratio showed no clear correlation with the prevailing erosion/deposition patterns. As the simulations offered insights into the prevailing hydrodynamics and thus the relevance of numerical modelling was emphasized for such complex sediment transport problems.
Optimising the wave attenuation of bamboo fences using the numerical wave model SWASH
Authors: Alferink Marijn , Gijon Mancheno Alejandra , Suzuki Tomohiro , Reniers Ad
Published: December 2023

Mangroves protect tropical coastlines from flooding and erosion, reducing flood risks along coastal communities worldwide. Nevertheless, mangrove forests have experienced considerable losses due to activities like urbanization and aquaculture, exposing coastal areas to wave attack. To restore mangroves at eroding coastlines, structures formed by bamboo poles and a brushwood filling are used to shelter the coast from waves, and create a favourable habitat for mangrove colonization. However, these structures often lose their brushwood filling during storms, resulting in high maintenance costs. This study proposes a new type of design to reduce maintenance expenses, consisting of only vertical bamboo poles without a filling of brushwood. Structure designs are evaluated for a case study in Demak, Indonesia, using the numerical wave model SWASH to predict wave attenuation through the structures. Field measurements and WaveWatch III data are analyzed to obtain the design conditions for the structures in Demak. SWASH is validated against laboratory experiments, and applied to investigate the optimum number of rows and their optimum spacing (in the direction of wave propagation). The model shows that for a structure consisting of two rows of bamboo poles, the transmission rate Et/Ei decreases from 75% to 55% when the row spacing in the wave direction is increased from sx = 0.42 m to sx = 5.8 m. Larger spacings do not result in less transmission, and at least three rows are needed to have a transmission rate lower than 50 % - a common wave reduction target used in restoration efforts with structures. This study thus identifies potential strategies to maximize wave attenuation by bamboo structures, which can be used to reduce wave attack along muddy coasts without the need of a brushwood filling. Hereby, it provides an economically and user friendly alternative with respect to the previous brushwood structure designs, as it requires less material costs and maintenance. In addition, this study presents a new method to schematize these kind of structures in SWASH in an efficient way.
Pravo na sindikalno udruživanje u praksi komiteta za sindikalne slobode
Authors: Nikolić Milica
Published: December 2023

The author, in the paper, points out the importance of the practice of the Committee of Association of the International Labour Organization, which is the cornerstone of modern collective labor law. The recommendations of the Committee regarding the realization and protection of trade union freedoms greatly influenced the adoption and amendment of legal regulations in a large number of countries, which were not in accordance with the ratified Conventions no. 87 on freedom of association and protection of the right to organize, as well as Convention no. 98 on the right to organize and collective bargaining, and where in practice there were restrictions and impediments to the enjoyment of trade union freedoms. In the first part of the paper, the author deals with the right to union association and its guarantees in the legal instruments of the International Labour Organization. Furthermore, the paper analyzes the establishment, composition and jurisdiction of the Committee of Association of the International Labour Organization, while special attention is paid to the procedure before the Committee itself. The central part of the paper refers to the practice and opinions of the Committee, while in the last part of the paper, the author deals with protection against anti-union discrimination.
Diskriminacija ruske nacionalne manjine kao osnov za rat u Ukrajini
Authors: Tadić Sara
Published: December 2023

The paper examines the validity of the arguments used to justify the war in Ukraine. It starts from the discourse that supports the war. In Vladimir Putin’s speeches, the genocide against the Russians in Ukraine and the disrespect of the people’s right to self-determination are cited as a justification for the start of the conflict. The paper then points out the international legal framework of warfare, specifically under what conditions armed conflict is allowed, as well as what is the right of the people to self-determination and what are its limitations. The fourth part analyzes the reports dedicated to Ukraine by international monitoring bodies – the European Commission against Racism and Intolerance and the Advisory Committee under the Framework Convention for the Protection of the Rights of Members of National Minorities. By critically reviewing the arguments that appear in that conflict, this paper enables a comprehensive understanding of the degree of their compliance with international law. The paper ends with the conclusion that the degree of discrimination against ethnic Russians in Ukraine is not sufficient for the application of the concept of remedial secession and that the Russian military intervention in Ukraine is a violation of international provisions on the use of force.
Experiências avaliativas com uso de tecnologias dos estudantes de Educação Física no programa Residência Pedagógica
Authors: Ribeiro Samia Maria Silva , Sousa Janiele Santos de , Sousa de Almeida Grasiany , Cruz Eliana Costa da , Silva Solonildo Almeida da
Published: December 2023

O estudo objetivou investigar as experiências avaliativas com uso de tecnologias dos estudantes de licenciatura em Educação Física no âmbito do Programa Residência Pedagógica (PRP). A pesquisa é de abordagem qualitativa. Participaram do estudo 12 estudantes de Educação Física que participaram do PRP. Para coleta e análise de dados foi utilizada uma entrevista semiestruturada e a análise temática. Diante disso, foi evidenciado que a avaliação não deve se limitar apenas ao método tradicional, mas na utilização de metodologias avaliativas por meio do uso das tecnologias. Assim sendo, o PRP contribuiu para a formação inicial, uma vez que enfatizou a relevância da utilização de novas ferramentas para criar, avaliar e transformar prática docente a partir da inserção de metodologias inovadoras no contexto da avaliação. Deste modo, conclui-se que o programa promoveu vivências avaliativas significativas aos futuros professores por meio da utilização das tecnologias ainda na formação inicial.
Os impactos do Covid-19 para a satisfação acadêmica de estudantes da UNESP
Authors: Nogueira Bianca Lopes da Cunha , Osti Andréia
Published: December 2023

A pandemia do Covid-19 impactou toda a sociedade mundial, ao tratar das universidades brasileiras, não foi diferente. O novo contexto exigiu uma nova organização em termos de promover o ensino em razão da necessidade de distanciamento social. Neste sentido, este estudo se dedicou a realizar uma investigação de caráter quantitativo sobre a temática da satisfação acadêmica no ensino superior visando identificar quais os fatores que envolvem a satisfação ou insatisfação dos estudantes com a vida acadêmica no contexto pandêmico. Participaram da pesquisa 300 estudantes da graduação das áreas de Humanas, Exatas e Biológicas graduandos da UNESP - Universidade Estadual Paulista - campus de Rio Claro. Metodologicamente foi aplicado um questionário composto por questões fechadas de escolha múltipla e a análise foi realizada por estatística descritiva. Os resultados mostram que a capacidade de envolvimento em atividades de aprendizagem foi afetada por fatores emocionais e materiais e impactou o acompanhamento das atividades acadêmicas.
Phytochemical Screening, Antioxidant, Anti-Inflammatory and Antibacterial Studies on the Stem Bark Extracts of Ximenia Americana Linn.
Authors: Umar Umar Meleh , Bashir Barkoma Mohammed c , Babalola Ibrahim Tijjani
Published: December 2023

Medicinal plants have been used in traditional medicine practices since pre-historical times. Any part of the plant could be used as medicine. A survey of traditional medicine men and women in Damaturu, Nigeria indicated that Ximenia americana is a plant used in the treatment of inflammation, wounds and cancer. The fresh stem barks of the plant were collected and successively extracted with n-hexane, ethyl acetate, methanol and water. Phytochemical constituents of the extracts revealed the presence of cardiac glycosides, flavonoids, saponins, phenols, tannins, alkaloids, sterols and terpenoids. The antioxidant activity was evaluated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical assay, whereas membrane stabilization method was used to evaluate the anti-inflammatory activities of the extracts. The antibacterial activity was studied against four (4) wound pathogens (Salmonella typhi, Staphylococcus aureus, Escherichia coli and Streptococcus pneumoniae), using disc diffusion technique. The results of the IC50 for antioxidant studies indicated that the methanol (22.4µg/ml) and ethyl acetate (28.4 µg/ml) extracts of X. americana exhibited higher antioxidant activities than the standard ascorbic acid (38,9µg/ml). The extracts were found effective in inhibiting the heat induced hemolysis in a concentration dependent manner. The n-hexane extract showed the highest protection level (84.41 – 87.98%, p<0.05), followed by water (46.73 – 82.38%, p<0.05) and ethyl acetate (71.3o – 77,39%, p<0.05) extracts. Diclofenac Sodium salt used as standard drug at 100μg/ml offered 90.66% protection a significant (p<0.05) protection against damaging effect of heat. The hypotonic solution induced study indicated that the extracts exhibited more protection from hemolysis (n-hexane = 75.22 – 85,23%, p<0.05; ethyl acetate = 4.09 – 71,40%, p<0,05; water = 59.98 – 67.08%, p<0.05, and methanol = 48.15 – 58.75%, p<0.05) than the standard Diclofenac sodium salt (57.52%, p<0.05). The results showed that all extracts from the plant offered a significant (p<0.05) protection against the damaging effect of hypotonic solution, Diclofenac sodium (100μg/ml), the standard drug offered a significant (p<0.05) protection (57.52%). X. americana samples showed that all extracts inhibited the growth of S. aureus, S. pneumoniae and E. coli. The antioxidant, anti-inflammatory and anti-bacterial activities carried out in this study can be used as scientific explanation for the traditional claim about the wound healing property of the stem bark of X. americana.
PENERAPAN TEKNOLOGI TEPAT GUNA PENGRAJIN TEMPE DUSUN LATSARI UNTUK MENINGKATKAN PRODUKTIVITAS
Authors: Wulandari Lusi Mei Cahya , Patrick Johan , Yoseph Deograsias , Sumewang Filippo
Published: December 2023

Dalam menghadapi persaingan yang ketat, UMKM tempe perlu memperhatikan penataan fasilitas produksinya. Penataan fasilitas produksi yang baik dan tertata rapi membantu meningkatkan efisiensi proses produksi. Hal ini berdampak pada kualitas tempe sehingga memenuhi standart yang ditetapkan.

Desa Mlirip kecamatan Jetis, Mojokerto memiliki tujuh Industri Rumah Tangga (IRT) Tempe dengan produksi terbesar di Dusun Latsari, milik pak Riono dengan produksi minimal 600 kg per hari.  Permasalahan yang dihadapi mitra adalah proses pencucian kedelai dilakukan dengan tenaga manusia, yang berdampak pada kelelahan karyawan dan kurang hygienis.

Tujuan yang ingin dicapai dalam Program Kemitraan Masyarakat ini adalah meningkatkan produktivitas pengrajin tempe melalui pembuatan mesin pencuci kedelai sehingga proses produksi menjadi lebih cepat dan kualitas produk lebih terjaga. Tahapan yang dilakukan adalah membuat desain mesin pencuci dengan kapasitas 100kg, pabrikasi mesin, melakukan uji coba serta penerapan mesin di lantai produksi.

Hasil penerapan mesin pencuci kedelai mampu mempercepat waktu proses sehingga  memberikan penghematan biaya pencucian sebesar 27,70% serta memberi dampak meringankan kerja operator pada usaha tempe dusun Latsari.
HUBUNGAN GANGGUAN FUNGSI TIROID TERHADAP KADAR LDL-KOLESTEROL
Authors: Arie Gristine Arie , Santoso Setyo Dwi , Santosa Rahajoe Imam
Published: December 2023

Hormon tiroid mempunyai peran yang penting terhadap berbagai proses metabolisme tubuh (protein, karbohidrat, lipid) dan aktivitas fisologis pada hampir seluruh organ tubuh manusia. Kekurangan atau kelebihan hormon tiroid dapat mengganggu metabolisme organ tubuh. Hipotiroid merupakan suatu keadaan dimana hormon tiroid di jaringan tubuh menurun, sedangkan hipertiroid adalah kelebihan hormon tiroid yang beredar dalam sirkulasi akibat kelenjar tiroid yang hiperaktif. Hal tersebut juga memberikan efek spesifik terhadap metabolisme lipid. Pada gangguan fungsi tiroid, metabolisme lipid akan terganggu sehingga menimbulkan faktor resiko penyakit kardiovaskular salah satunya arterosklerosis (penyumbatan/plak) pada pembuluh darah. Pada kasus kelainan   hipotiroid seringkali terjadi peningkatan kadar LDL-Kolesterol sedangkan hipertiroid seringkali terjadi penurunan kadar LDL-Kolesterol.Diagnosa gangguan fungsi tiroid pemeriksaan laboratorium FT4 dan TSH menjadi standar penegakkan diagnosa tiroid yang tepat. Penelitian ini bertujuan untuk melihat hubungan gangguan tiroid terutama FT4 dan TSH terhadap kadar LDL-Kolesterol. Penelitian menggunakan data deskriptif yang diambil di Laboratorium Klinik Pramita Surabaya pada bulan Januari – Desember 2019. Data dikumpulkan berasal dari rekam medis pasien yang melakukan pemeriksaan FT4, TSH dan LDL-Kolesterol sebanyak 80 orang yang terdiri dari 22 laki-laki dan 58 perempuan dengan rentang usia 22-81 tahun. Dari data diperoleh karakteristik jenis kelamin laki-laki (27,5%), perempuan (72,5%). Pada kelainan hipertiroid diperoleh rerata kadar TSH (0,0612 µIU/mL), FT4 (1,53 ng/dl), LDL-Kolesterol (99 mg/dl) sedangkan hipotiroid rerata kadar TSH (17,427 µIU/mL), FT4 (0,92 ng/dl), LDL-Kolesterol (130 mg/dl). Analisa korelasi bivariat digunakan untuk melihat hubungan antara kadar FT4 dengan LDL-Kolesterol serta TSH dengan LDL-Kolesterol. Dari data yang diperoleh didapatkan korelasi positif antara kadar TSH dan LDL-Kolesterol pada kelainan hipotirod serta korelasi  negatif antara kadar FT4 dan LDL pada hipertiroid. Dalam penelitian ini menunjukkan hasil gangguan fungsi tiroid berpengaruh pada peningkatan/penurunan kadar LDL Kolesterol.
GONADOTROPIN, ANTI MULLERIAN HORMON DAN ESTRADIOL PADA SINDROM OVARIUM POLIKISTIK
Authors: Setiani Maria Tri , Santoso Setyo Dwi , Santosa Rahajoe Imam
Published: December 2023

PCOS (Polycystic Ovary Syndrome) is an endocrine disorder characterized by anovulation and hyperandrogenism. It was found that about ±10% of women of reproductive age cause infertility so that it becomes a burden for partners physically, psychologically and materially. Increasing age affects a woman's fertility and menstrual cycle. The menstrual cycle in women is influenced by hormones, depression, weight, and lifestyle. Gonadotropin Releasing Hormone (GnRH) is released by the hypothalamus through a secretory process every 90 – 120 minutes which then binds to gonadotropin cells and stimulates Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH). FSH, LH levels will increase after puberty, FSH, LH, Anti Mullerian Hormone (AMH) and estradiol are very important in folliculogenesis. However, the interactions between the four hormones are not yet fully understood. The purpose of this review was to determine the correlation between LH/FSH Ratio, AMH and Estradiol in women with Polycystic Ovarian Syndrome (PCOS). This understanding is expected to increase knowledge about the pathophysiology of PCOS. This study uses secondary data from the Pramita Surabaya Clinic laboratory which is examined for reproductive hormones. Data from 228 women aged < 35 years with an average LH/FSH ratio (0.61), AMH (3.56 ng/dL), and estradiol (34.42 pg/mL) and 172 women aged 35 years with a mean ratio of LH/FSH (0.54), AMH (2.93 ng/dL), and estradiol (36.60 pg/mL). LH, FSH, AMH and Estradiol examinations were performed on the 2-4th day of menstruation. Bivariate correlation analysis was used to see the relationship between AMH and the LH/FSH ratio and AMH and estradiol. From the results, there was a positive correlation between the AMH value and the LH/FSH ratio and a positive correlation between AMH and Estradiol which showed that AMH had an effect on the secretion of LH, FSH and Estradiol. Keywords: infertility, LH/FSH, AMH, estradiol, SOPK
TUTELA JURISDICIONAL EFETIVA E A LIMITAÇÃO DA CONDENAÇÃO AO VALOR DA PETIÇÃO INICIAL NA JUSTIÇA DO TRABALHO: UMA ANÁLISE DA SUA APLICAÇÃO
Authors: Oliveira Leticia Marques de , Moreira Thiago Rodrigues
Published: December 2023

O presente trabalho trata sobre a tutela jurisdicional e a limitação da condenação aos valores indicados na petição inicial, tendo como premissa a seguinte indagação: os valores indicados na petição inicial são de caráter limitativos ou apenas facultativos?  Assim, o estudo tem como objetivo, analisar as questões teóricas e práticas relacionadas ao tema na seara trabalhista, e, de modo geral a limitação da condenação que deve se ater pelo mérito apresentado pela parte, porém, há casos relevantes que essa regra não é considerada pelo magistrado. Diante disso, o presente trabalho busca sanar o respectivo impasse, analisando jurisprudências sobre o tema, no site dos Tribunais trabalhistas, afim de identificar as relações estabelecidas entre os pedidos e a decisão. O referido trabalho concluiu que apesar dos benefícios trazidos pela limitação da condenação aos valores elencados pela exordial, é inegável a necessidade de considerar que os valores são meramente consultivos, para contudo, alcançar a efetividade da\’+ justiça nos conflitos laborais. Trata-se de uma pesquisa jurisprudencial e bibliográfica de cunho qualitativa e amparada no arcabouço teórico de Fagner Sandes (2020); Antônio Gil (2002); Carlos Henrique Bezerra Leite (2022); Antônio de Paula Rocha (2023) dentre outros que irão complementar o tema.
A IMPORTÂNCIA DA PSICANÁLISE NO BANCO DE SANGUE: UM OLHAR DIFERENCIADO
Authors: Cunha Emanuelle Xavier , Silva Diego da
Published: December 2023

A psicanálise desempenha um papel crucial no contexto do banco de sangue, promovendo uma compreensão mais profunda e holística dos doadores e receptores de sangue. Ao explorar os aspectos inconscientes e emocionais dos doadores, os psicanalistas ajudam a identificar medos, ansiedades ou traumas relacionados à doação de sangue, o que pode influenciar a disposição das pessoas em doar. Compreender esses fatores subjacentes é fundamental para melhorar as taxas de doação, criando um ambiente mais acolhedor e empático para os doadores. Além disso, a psicanálise também é valiosa ao lidar com os pacientes que recebem transfusões sanguíneas. Pacientes que passam por procedimentos intensivos muitas vezes enfrentam medo, angústia e vulnerabilidade. Os psicanalistas podem ajudar esses pacientes a lidar com essas emoções, o que pode, por sua vez, melhorar sua resposta ao tratamento e acelerar o processo de recuperação. Ao integrar a psicanálise no contexto do banco de sangue, os profissionais de saúde podem estabelecer uma conexão mais profunda com os doadores e receptores, garantindo um processo de doação mais humano e compassivo. Esta abordagem centrada no paciente não apenas aumenta as doações de sangue, mas também contribui para o bem-estar emocional e mental tanto dos doadores quanto dos receptores, melhorando significativamente a qualidade. A psicanálise no banco de sangue não apenas promove a doação regular, mas também cria um ambiente onde as pessoas se sentem compreendidas e apoiadas. Essa compreensão emocional pode aumentar significativamente a disposição das pessoas para doar sangue, resultando num suprimento mais estável e salvando vidas.
ATRIBUIÇÕES DO FARMACÊUTICO NO CUIDADO AO PACIENTE COM TUBERCULOSE: ANÁLISE DOCUMENTAL DE CASOS NOTIFICADOS NO EXTREMO SUL BAIANO DE 2019 A 2022
Authors: Magalhães Luana Krystal Alcântara , Silva Cecilia Simon da
Published: December 2023

A tuberculose (TB) é uma doença infecciosa que afeta principalmente os pulmões, e que usualmente demanda tratamento prolongado e acompanhamento por especialista capacitado. Nesse aspecto, o farmacêutico é um profissional de saúde que possui qualificação para monitorar e orientar o paciente, a fim de minimizar efeitos colaterais e reduzir taxas de abandono ao tratamento. No contexto de assistencialismo e atenção à saúde, questiona-se: Como o profissional farmacêutico pode contribuir com o tratamento do paciente acometido por tuberculose pulmonar? Dessarte, o presente estudo tem por objetivo geral elencar as atribuições do farmacêutico no cuidado de pacientes portadores de tuberculose pulmonar. Os objetivos específicos são: identificar o padrão de ocorrência de casos ativos de tuberculose pulmonar nas cidades de Itamaraju, Teixeira de Freitas e Prado (extremo sul baiano) no intervalo de 2019 a 2022; relacionar os casos de tuberculose pulmonar com outras patologias; elencar a adesão às estratégias de diagnose e monitoramento usadas nos pacientes com TB. O presente estudo adotou metodologia de natureza básica, de procedimento documental, com abordagem quanti-qualitativa. Dados qualitativos foram obtidos pela análise dos referenciais teóricos por meio de consulta de livros de referências e artigos publicados em revistas, e os quantitativos, obtidos em documentos do Sistema DataSUS®, para atender os objetivos exploratórios.  Os resultados evidenciaram maior taxa de contaminação por TB em homens, e que houve uma sutil diminuição do número de casos da doença em 2020, no período pandêmico, sem variação significativa em relação aos demais anos em estudo nas referidas cidades. Os óbitos por outras doenças associadas também foram maiores em 2021 e 2020 (11 e 6 casos, respectivamente). A taxa de abandono ao tratamento aumentou e chegou a duplicar (de 8 para 16 casos), considerando o intervalo de 2019 a 2022, bem como, as taxas de cura para a doença reduziram ao longo dos anos (110 casos para 90). Esses resultados se associam diretamente com a baixa taxa de Tratamento Diretamente Observado (TDO) prestada aos pacientes, de apenas 14%, sendo que 38,24% dos casos listados no Sistema DataSUS® não receberam assistência do TDO. O farmacêutico pode ser uma ferramenta importante na melhoria da qualidade de vida e da adesão à terapia do paciente com tuberculose, atuando na dispensação e orientação sobre o uso dos medicamentos, realização de exames laboratoriais, monitorização terapêutica e a notificação dos casos. Adicionalmente, pode colaborar com ações educativas e de promoção da saúde, visando a prevenção e controle da doença no cenário local.
GESTÃO DEMOCRÁTICA NO CONTEXTO ESCOLAR: CONTRADIÇÕES E DESAFIOS DO PME-CODÓ-MARANHÃO
Authors: Serra Deuzimar Costa , Costa Cristiane Dias Martins da , Silva José Carlos Aragão
Published: December 2023

Este trabalho se materializou a partir de estudos e reflexões acerca da gestão democrática na escola e como essa experiência tem se efetivado no município de Codó-Maranhão, tendo como eixo norteador, o Plano Municipal de Educação-PME, Lei nº 1.727 de 23/06/2015. Os desafios encontrados no âmbito da gestão escolar por meio das concepções dos gestores em relação aos processos da Gestão Democrática também são analisados neste texto. A pesquisa interpretou, ainda, o contexto da aprovação do “Plano Municipal de Educação – PME”, sua efetivação e desafios. Em suma, este artigo contempla os estudos sobre a gestão democrática no enfoque das políticas educativas como ação pública, tendo como referência, teóricos que investigam e discutem sobre essa área, considerando a Lei de Diretrizes e Bases da Educação, além de interpretar documentos legais do PNE, PEE, PME, dentre outros que contemplam essa temática.
PENGGUNAAN TEKNOLOGI AUGMENTED REALITY UNTUK MENINGKATKAN PENGALAMAN PELANGGAN DALAM PEMASARAN PRODUK REAL ESTATE
Authors: Parman Suhadi , Fahrudin Rifqi , Lesmana Muhammad Angga , Putra Panji Satrio Randika
Published: December 2023

Augmented Reality (AR) telah menjadi teknologi yang penting dalam berbagai bidang, termasuk bidang Real Estate. Dalam industri Real Estate, pengalaman pelanggan menjadi fokus utama dalam memilih properti. Sayangnya, media tradisional seperti foto dan video sering kali kurang interaktif, menghasilkan pengalaman yang kurang memuaskan bagi konsumen. Untuk mengatasi masalah ini, diperlukan solusi inovatif yang memungkinkan pelanggan untuk mengalami properti secara lebih mendalam dalam pemasaran. Penelitian ini bertujuan untuk mengembangkan aplikasi Augmented Reality pada perangkat smartphone yang bertujuan meningkatkan pengalaman pelanggan dalam memahami dan memilih produk Real Estate di Perumahan Griya Jati Kalijaga. Aplikasi ini memungkinkan konsumen untuk secara instan melihat properti yang dimunculkan secara digital dalam lingkungan fisik dunia nyata. Selain itu, aplikasi ini memberikan pengalaman interaktif yang memungkinkan pengguna untuk menjelajahi setiap ruangan dalam desain properti yang ditampilkan. Pendekatan yang digunakan dalam pengembangan aplikasi Augmented Reality ini adalah System Development Life Cycle (SDLC). SDLC melibatkan prosespengumpulan data, analisis data, perancangan, pembangunan, implementasi, dan pengujian sistem. Metode ini digunakan untuk memastikan bahwa aplikasi dapat dikembangkan dengan baik dan sesuai dengan kebutuhan pengguna. Hasil dari penelitian ini adalah aplikasi Augmented Reality yang dinamakan AREST (Augmented Reality Real Estate). Aplikasi ini memungkinkan pengguna untuk melihat properti dalam bentuk unit 3D dengan proporsi 1:1 dalam kondisi dunia nyata. Selain itu, terdapat fitur tambahan yang memungkinkan pengguna untuk menjelajahi ruangan dalam mode gambar 360 derajat. Aplikasi AREST dirancang untuk memberikan pengalaman yang lebih mendalam dan memuaskan bagi konsumen dalam memilih properti. Aplikasi AREST diharapkan dapat membantu Perumahan Griya Jati Kalijaga dalam menarik lebih banyak calon pembeli dan meningkatkan daya saing dalam industri Real Estate yang kompetitif.Kata kunci: Augmented Reality, Real Estate, Pemasaran, Interaktif, SDLC
Future tropospheric ozone budget and distribution over east Asia under a net-zero scenario
Authors: Hou Xuewei , Wild Oliver , Zhu Bin , Lee James
Published: December 2023

Abstract. Under future net-zero emission policies, reductions in emissions of ozone (O3) precursors are expected to alter the temporal and spatial distributions of tropospheric O3. In this study, we quantify changes in the tropospheric O3 budget and in the spatiotemporal distribution of surface O3 in east Asia and the contributions of regional emissions, intercontinental transport and climate change between the present day and 2060 under a net-zero scenario using the NCAR Community Earth System Model (CESM) with online tagging of O3 and its precursors. The results reveal that the global tropospheric O3 burden is likely to decrease by more than 20 %, from 316 Tg in the present day to 247 Tg in 2060, under a net-zero scenario. The burden of stratospheric O3 in the troposphere is expected to increase from 69 to 77 Tg. The mean lifetime of tropospheric O3 is expected to increase by 2 d (∼10 %). Changes in climate under a net-zero pathway are relatively small and only lead to small increases in tropospheric O3. Over eastern China, surface O3 increases in winter due to the weakened titration of O3 by NO associated with reduced anthropogenic NO emissions and due to enhanced stratospheric input. In summer, surface O3 decreases by more than 30 ppbv, and peak concentrations shift from July to May. Local contributions from anthropogenic emissions to surface O3 over east Asia are highest in summer but drop substantially, from 30 % to 14 %, under a net-zero scenario. The contribution of biogenic NO sources is enhanced and forms the dominant contributor to future surface O3, especially in summer (∼40 %). This enhanced contribution is mainly due to the increased O3 production efficiency under lower anthropogenic precursor emissions. Over eastern China, local anthropogenic contributions decrease from 50 % to 30 %. The decreases in surface O3 are strongly beneficial and are more than sufficient to counteract the increases in surface O3 observed in China over recent years. This study thus highlights the important co-benefits of net-zero policies that target climate change in addressing surface O3 pollution over east Asia.
Extension of a high temporal resolution sea level time series at Socoa (Saint-Jean-de-Luz, France) back to 1875
Authors: Khan Md Jamal Uddin , Van Den Beld Inge , Wöppelmann Guy , Testut Laurent , Latapy Alexa , Pouvreau Nicolas
Published: December 2023

Abstract. In this data paper, the sea level time series at Socoa (Saint-Jean-de-Luz, southwestern France) is extended through a data archaeology exercise. We conducted a comprehensive study of national and local archives to catalogue water level records stored in ledgers (handwritten record books) and charts (marigrams from mechanical float gauges), along with other associated documents (metadata). A dedicated effort was undertaken to preserve more than 2000 documents by archiving them in digital formats. Using this large set of rescued documents, the Socoa time series has been extended back to 1875, with more than 58 station-years of additional data. The final time series has hourly sampling, while the raw dataset has a finer sampling frequency of up to 5 min. By analysing precise levelling information, we assessed the continuity of the vertical datum. We also compared the new century-long time series to nearby tide gauge data to ensure its datum consistency. While the overall quality of the time series is generally good, siltation of the stilling well has occasionally affected certain parts of the record. We have successfully identified these impacted periods and flagged the corresponding data as doubtful. This extended high-resolution sea level time series at Socoa, spanning more than 100 years, will be valuable for advancing climate research, particularly when studying the decadal-scale variations in the North Atlantic and investigating the storminess and extreme events along the French Basque coast. The raw digitized water level, the processed dataset, metadata, and the python notebooks used for processing are available at https://doi.org/10.5281/zenodo.7438469 (Khan et al., 2022).
Closing the data gap: runoff prediction in fully ungauged settings using LSTM
Authors: Hashemi Reyhaneh , Javelle Pierre , Delestre Olivier , Razavi Saman
Published: December 2023

Abstract. Prediction in ungauged basins (PUB), where flow measurements are unavailable, is a critical need in hydrology and has been a focal point of extensive research efforts in this field over the past two decades. From the perspective of deep learning, PUB can be viewed as a scenario where the generalization capability of a pretrained neural network is employed to make predictions on samples that were not included in its training data set. This paper adopts this view and conducts genuine PUB using long short-term memory (LSTM) networks. Unlike PUB approaches based on k-fold training-test technique, where an arbitrary catchment B is treated as gauged in k−1 rounds and as ungauged in one round, our approach ensures that the sample for which the PUB is conducted (the UNGAUGED sample) is completely independent from the sample used to previously train the LSTMs (the GAUGED sample). The UNGAUGED sample includes 379 catchments from five hydrological regimes: Uniform, Mediterranean, Oceanic, Nivo-Pluvial, and Nival. PUB predictions are conducted using LSTMs trained both at the regime level (using only gauged catchments within a specific regime) and at the national level (using all gauged catchments). For benchmarking the performance of LSTM in PUB, four regionalized variants of the GR4J conceptual model are considered: spatial proximity, multi-attribute proximity, regime proximity, and IQ-IP-Tmin proximity, where IQ, IP, and Tmin are the indices defining the five hydrological regimes. To align with the study's fully ungauged context, the IQ index, which is also an input feature for the LSTMs, and the regime classification, crucial for the REGIME LSTMs, are reproduced under ungauged conditions using a regime-informed neural network and an XGBoost multi-class classifier respectively. The results demonstrate the overall superior performance of NATIONAL LSTMs compared to REGIME LSTMs. Among the four regionalization approaches tested for GR4J, the IQ-IP-Tmin proximity approach proves to be the most effective when analyzed on a regime-wise basis. When comparing the best-performing LSTM with the best-performing GR4J model within each regime, LSTMs show superior performance in both the Nival and Mediterranean regimes.
Sea Level Rise in Europe: Impacts and consequences
Authors: van de Wal Roderik S. W. , Melet Angélique , Bellafiore Debora , Vousdoukas Michalis , Camus Paula , Ferrarin Christian , Oude Essink Gualbert , Haigh Ivan D. , Lionello Piero , Luijendijk Arjen , Toimil Alexandra , Staneva Joanna
Published: December 2023

Abstract. Sea level rise has major impacts in Europe which vary from place to place and in time depending on the source of the impacts. Flooding, erosion and saltwater intrusion lead via different pathways to various consequences in coastal regions across Europe. Flooding leads via overflow, overtopping and breaching to damage to assets, environment and people. Erosion leads via cliff failure along a different pathway also to damage and saltwater intrusion affects ecosystems and surface waters and salinizes existing fresh water resources diminishing fresh water availability causing salt damage to crops and health issues to people. This paper provides an overview of the various impacts in Europe.