bluuebunny/crossref_metadata_2025 huggingface dataset:
The COVID-19 delta or detrimental variant?
Authors: Priyadarshi Surbhi , Tangade Pradeep , Sahar Najmus , Srivastava Rangoli
Published: June 2022

The delta variant of COVID-19 also known as B.1.617.2 is more contagious than the alpha variant and henceforth this variant has led to a sudden spike in the cases of COVID-19 all over the world. It is indeed a matter of surprise that in countries where most of the population were vaccinated, still there was an upturn in the number of COVID-19 infections. Though some of the vaccine companies have reported that their vaccine can effectively provide shielding against this variant too, but still we need to understand why is this variant more transmissible and how did it became a dominant strain in such a short span of time and what are the measures that can be taken to prevent the most widely spread delta-variant of this virus. An overall review regarding the delta B.1.617.2 variant along with its pathogenicity is done in this article.
A roadmap for scientific publications – Part I
Authors: Ashok K  , Rao Suneetha , Swetha M U  , Mishra Shruti , Jyothi S  , Eshwar Prerana
Published: June 2022

Scientific publications are the foundation for all research activities in their respective fields. They help in sharing original research work with others and to review the research work done. They become the most important factor for the evolution of modern day science where one researcher builds his work based on others research thereby creating scope for further improvement. There are many scientific publications carried out constantly in different journals and print media. But only few articles give the details necessary to be looked into before publication, and they are also specific for any particular topic or subtopic, Hardly any article is there which gives the complete detail which a researcher needs to know before publishing his/her article. This article gives the details to be looked into before, during and after for publication of the study. It helps in making the researchers life easy by compiling all the details in a nut shell there by paving a road map for easy and hastle free publication of the articles.

For convenience sake these are published in two parts. In this first part details of various types of Scientific research, studies, sampling methods and calculations, graphical representation of results and the various analytical tests are described.
A roadmap for scientific publications-part II
Authors: Ashok K  , Rao Suneetha , Swetha M U  , Mishra Shruti , Jyothi S  , Eshwar Prerana
Published: June 2022

Scientific publications are the foundation for all research activities in their respective fields. They help in sharing original research work with others and to review the research work done. They become the most important factor for the evolution of modern day science where one researcher builds his work based on others research thereby creating scope for further improvement. There are many scientific publications carried out constantly in different journals and print media. But only few articles give the details necessary to be looked into before publication and they are also specific for any particular topic or subtopic. Hardly any article is there which gives the complete detail which a researcher needs to know before publishing his/her article. This article gives the details to be looked into before, during and after for publication of the study. It helps in making the researchers life easy by compiling all the details in a nut shell there by paving a road map for easy and hastle free publication of the articles.

For convenience sake these are published in two parts. In this second part indexing, impact factor, DCI points for publication and plagiarism are described.
Maxillary labial frenum and malocclusion: An overriding or an overlooked tissue?
Authors: Rajani Elayadath R , Biswas P Palukunnu
Published: June 2022

The influence of the maxillary labial frenum in relation to the midline diastema has been a proven fact to clinicians for many years. A pilot study was carried out to investigate the relationship between a low maxillary labial frenum attachment and skeletal malocclusions (class I, II, and III). Astonishingly, it was observed that the class III malocclusion had a statistically high number of cases with low frenum attachments. The objective of the study was to understand the underlying skeletal class III dysplasia in these cases. A comparative cross-sectional study was performed on 300 consecutive subjects between 13-30-years of age. Based on the cephalometric parameters the participants were categorized into 98 skeletal class I, 102 class II, and 100 class III subjects. Variations in the frenum attachment were clinically evaluated using Placek classification. The insertion level and width of the frenum were also measured by using a caliper and the data were statistically analyzed for determining the association between the frenum attachment and skeletal malocclusion. The prevalence of low frenum attachment in class III subjects was found to be 64%. Also, the mean attachment level of the frenum was significantly closer to the gingival margin in skeletal class III subjects compared with that of the other groups (p<0.01). The study identified that the subjects with a low frenum attachment had a tendency towards a retruded maxilla in terms of linear dimension. Therefore the present study supports the hypotheses that the skeletal Class III malocclusion may be associated with low frenum attachment.
Recent trends in dental visits among socially insured group to a referral centre– A retrospective study
Authors: Sharma Rohini , Umashankar G K  , Rahman Shuhaib , Kunsi Somanath Reddy
Published: June 2022

: A retrospective analysis was undertaken to assess the recent trends in dental visits among socially insured group to a referral centre.

: The data was collected retrospectively from records and dental database of Employee state insurance unit of a referral centre in Karnataka from February 20, 2018 to March 10, 2018. A total of 558 study subjects’ data was recorded. Depending upon the nature of the data, the statistical tests were chosen according to SPSS. P value 0.005 was considered significant.

The minimum age was 4 and maximum was 75 with a mean and standard deviation of 32.27±12.90 years. There were 311(55.7%) males and 247(44.3%) females. A total of 321 (57.5%) of study subjects were self -benefited and 237(42.5%) were dependent of the employee. Out of the total 558 study subject’s majority 126 (22.6%) were referred for chronic apical periodontitis followed by 109(19.5%). Most of the subjects 188(33.7%) were treated for root canal. The minimum cost of the treatment received by the beneficiary was Rs. 240 and maximum was Rs.18055 with mean and standard deviation of Rs.2842.25±1939.8 respectively for the study subjects There was a strong significant association seen with cost and diagnosis of all dental diseases p>0.000 and cost and treatment of diseases p>0.000.

: The insurance coverage was beneficial to the subjects as it has reduced the burden of cost borne by the individual alone. Furthermore, it has made the treatment easily accessible, encouraging individuals to take treatment at the early stage, thus reducing the inequality
Evaluation of radiographic interpretation skills of undergraduate dental students studying in a dental college of Punjab, India – A comparative study
Authors: Aneja Abhinav , Singh Ravpreet , Bahal Megha , Rai Abhishek , Singh Jaspreet
Published: June 2022

Dental students must have enough knowledge and skills to identify anatomical structures and pathologies in radiographs so as to make better diagnosis about patient’s health. Aim of this study was to evaluate on comparative basis the level of radiograph interpretation skills among final year students and interns studying in a dental college of Punjab state.

A questionnaire was prepared for this study which contained 20 questions related to radio-diagnosis of normal anatomical structures and pathologies represented by 11IOPARs, 8 OPGs and 1 extra-oral radiograph.

Out of all interns and final year students- 65.1% of interns have correctly identified radiographs and 60.2% of final year students have gave correct responses.
Autotransplantation of conoid maxillary third molar in upper incisive site: A reliable aesthetic solution
Authors: Arcari Matteo , Tagliatesta Luigi , Lorenzoni Marco
Published: June 2022

In the management of anterior dental trauma, the maintenance of the traumatized elements has to be preferred, but sometimes this results impracticable. Among different options, autotransplantation provides an adequate therapeutic solution, particularly in crowded arches, in presence of supernumerary elements or when third molars with a root anatomy compatible with the recipient site are available.

: This paper presents a case of autotransplantation of a conoid upper third molar (1.8) inside the alveolus of a central incisor undergone at root resorption, after a long time maintenance of the traumatized element 2.1 and different treatments. Furthermore, a comparison of the therapeutic alternatives is proposed. 

: Due to their root anatomy, premolars and supernumerary monoradiculated teeth are adequate to be transplanted in incisors’ sockets. In the presented case, the presence of a conoid third molar consented the transplantation of the latter, which represented a more conservative treatment than transplanting a premolar. The use of a 3D-printed replica made through a CBCT scan permitted the substantial reduction of the extra alveolar time, avoiding the periodontal ligament contamination and guaranteeing a higher success rate. Due to the complete formation of the donor tooth, root canal treatment was carried out.

Autotransplantation represents a valid and biological alternative in the management of traumas of the anterior dental trauma.
Breaking the stress using pier abutment - A case report
Authors: Aeran Himanshu , Kesavan Aishwarya , Singla Varun , Seth Jyotsna
Published: June 2022

A pier abutment is the lone standing abutment tooth between two critically situated edentulous spaces, in a frequently seen clinical situation, a missing first premolar and first molar is seen, which leads to a design where canine and the second molar acts as a terminal abutments and second premolar acts as a pier abutment. This pier abutment acts as a fulcrum which may lead to debonding of the less retentive terminal abutment during function, to overcome this situation a non rigid connector is advised. This paper presents a clinical case report which describes the incorporation of non rigid connector to rehabilitate the pier abutment case in unilateral maxillary and mandibular region.
Treatment of severe crowding with constricted arches in a patient with high angle Class I malocclusion: A case report
Authors: Younus A Abrar , Ahmed Nausheer , Joseph Rithika , Bhat K Ranjan R , Nikhil P M  , Haritha U
Published: June 2022

The goal of orthodontic treatment in a severely crowded malocclusion is to obtain a harmonious face with a well-balanced soft tissue profile, functional occlusion and a consonant smile. Etiology involving both genetic and non-genetic factors are associated with severe crowding. This case report is on correction of class I severely crowded malocclusion in a vertical grower treated with extraction of all first premolars. Intra oral, extra oral and radiographic examination revealed skeletal Class I with straight profile, hyper divergent growth pattern, increased overjet and severe crowding in maxillary and mandibular dentition, constricted arches, potentially competent lips with increased lip strain and a non-consonant smile arc, treated with extraction of all 1st premolars, significant improvement in patient's smile, profile and occlusion were obtained. The successful results were obtained due to correct case selection and proper treatment planning. The meticulous space analysis and management without anchorage loss is a result of proper anchorage planning prior to extractions.
Brachiobasilic Fistulas Superficialization with Minimal Incisions: A New Approach by Very Good Outcomes
Authors: Hassani Mohammad , Marashi Seyed Ali , Shahrebabaki Peyman Bakhshaei , Salehian Mohammadtaghi , Hassanzadeh Katayon
Published: June 2022

Background: Failure of cannulation due to the unavailability of deep veins is one of the complicated problems for chronic hemodialysis patients. By using superficialization, the veins with larger caliber and intact intima will be available for continuing the dialysis process. Brachio-Basilic superficialization with Minimal Incision (BBMI) is a proposed method that its patency and results are explored in the current study.
Methods: Thirty hemodialysis patients with two-step superficialization indication were evaluated. For BBMI, first by using sonography, basilic vein pathway was marked and with three small incisions matured basilic vein explored and transected near pervious anastomosis and transposed from new subcutaneous tunneling and re-anastomosed the vein. In a definitive time period up to 6 months, the study variables were evaluated.
Results: There were 11 females and 19 males. The minimum and maximum ages were 29 and 92. Technical success was 100%. After passing several successful dialysis sessions from the superficialized vein, 2 patients (6.7%) encountered unsuccessful cannulation due to thrombosis, and one of thrombosis events was due to hypotension. These cases were whom with the shortest interruption between surgery and dialysis initiation (18 and 25 days; mean±SD=28.63 ±7.36 days). There were no cases of infection and pseudoaneurysm. Furthermore, 1 case (3%) experienced wound dehiscence that managed using proper wound care.
Conclusion: BBMI could be utilized safely with a high patency. This method has the lowest complications. The minimal side effects are affected by predisposing factors that should be clarified precisely in future studies and by gathering more evidence.
Evaluating Efficacy, Specificity, and Sensitivity of Liver Enzymes Levels for Early Diagnosis of Acute Appendicitis and its Complications
Authors: Motamed Hassan , Fatahian Nejad Maryam
Published: June 2022

Background: The most common etiology for patients with acute abdominal pain presenting in emergency departments is acute appendicitis. This study aimed to evaluate the effectiveness of liver enzymes in early diagnosis of acute appendicitis and prediction of its complications.
Methods: 176 patients with the chief complaint of abdominal pain presented in the emergency departments were enrolled in this study. All included patients underwent standard approach for acute abdomen with target focus for appendicitis. Samples for serum levels of ALT and AST on arrival have been arranged for all included. Patients were evaluated for appendicitis and diagnosis confirmed by histopathology. AST, ALT variables and confirmed diagnosis of acute appendicitis, and related complications have been evaluated for any correlations using Kruskal-Wallis test.
Results: Based on the results, 67 simple, 24 complicated appendicitis, and 85 cases of normal appendix were evaluated. The mean AST was significantly different in normal, simple appendicitis, and complicated groups (p=0.019), but the mean ALT failed to show a significant difference. The differential test showed that there was a significant difference between the two appendicitis groups and the normal group in AST (p<0.05), but not between the two appendicitis groups. The p-values of AST and ALT were 0.17 and 0.2, respectively.
Conclusion: According to the results of this study, it seems that increased AST may be increased in simple/complicated appendicitis in contrast to normal group, but regarding AUC curve data, AST and ALT fail to have the necessary diagnostic accuracy and efficiency to diagnose acute appendicitis and predict its complications.
Double-lumen Tube Position Confirmation with Fiberoptic Bronchoscope after Turning Patients into Lateral Position: Is It Necessary?
Authors: Mireskandari Seyed Mohammad , Darabi Golnaz , Rafieian Shahab , Jafarzadeh Afshin , Karvandian Kasra , Makarem Jalil
Published: June 2022

Background: Our goal was to compare two common methods including auscultation and Fiber-Optic Bronchoscopy (FOB) in confirming the correct placement of Double-Lumen Tube (DLT).
Methods: Seventy six patients were enrolled. After DLT insertion, clinical verification was made by auscultation, then FOB was applied. At lateral decubitus, the position of DLT was rechecked by auscultation, and then by FOB. The incorrect position including malposition and misplacement were compared between two routine methods of auscultation and FOB.
Results: After blind intubation, 21.1% of DLTs were considered to be in an incorrect position. Meanwhile, FOB showed that 46.1% of DLTs were not placed correctly. Among all the patients, 53.9% of DLTs were in the optimal position. Misplacement was diagnosed in 35.5% and malposition in 10.5% of the patients. After positioning to the lateral decubitus, using auscultation, we found that 5.3% of tubes were dislocated, but according to FOB, it was 10.5%. The agreement coefficient between auscultation and FOB was 0.42 in the supine position and 0.64 in lateral position.
Conclusion: Our results showed that although FOB needs more time to check the position of DLT, it should be used to confirm the exact position of DLT.
Has COVID-19 Affected Medical Errors and Medical Ethics?
Authors: Bamir Mousa , Farahbakhsh Salman , Daneshi Salman
Published: June 2022

The Article Abstract is not available.
Influence of the Number of Starts of the Thread on the Drive Nut of the Planetary Roller-Screw Drive on the Efficiency of the Mechanism
Authors: Ryahovskiy O.A. , Romanov N.O.
Published: June 2022

Planetary roller screw mechanisms are designed to smoothly convert the rotational movement of the nut into the translational movement of the screw due to the presence of threaded rollers located between the internal thread of the drive nut and the external thread of the driven screw. The position of the rollers around the circumference is determined by two separators located at the ends of the rollers. Smooth cylindrical holes in separators are matched by clearance fit. Both ends of the threaded rollers have gears that mate with the gears at the ends of the screw. Thus, rotating rollers are located between the screw and the nut, and the sliding friction of the threads of the ordinary screw and nut in the planetary roller-screw mechanism is replaced by rolling friction. Friction losses during the operation of the mechanism are significantly reduced. Bearing capacity of the mechanism is increased due to a significant number of contact points in the threads of the nut, screw and rollers. By varying the pitch and setting the thread number of starts on the screw and nut the speed of the axial movement of the screw relative to the nut of the mechanism is regulated. Increasing the thread number of starts on the nut and screw increases the efficiency of the mechanism under study. Increasing a number of starts of the thread on the nut and screw increases the efficiency of the mechanism under study.
Analysis of the Operating Modes of the Hybrid Underwater Robotic System
Authors: Veltishchev V.V. , Aladysheva E.I.
Published: June 2022

In the modern world, performing oceanological research and underwater technological operations is impossible without using autonomous and remotely operated underwater vehicles. However, each of these types of vehicles has disadvantages limiting their application and allowing only narrow-profile tasks to be performed. To solve this problem, it is proposed to use a hybrid underwater robotic complex consisting of an autonomous and remote-controlled vehicles connected with a cable. The functionality of the proposed hybrid complex is determined. The results of the analysis of the mathematical models of hybrid complex operation in the modes of joint movement and towing are presented. Due to the restrictions imposed on the remotely controlled underwater vehicle and the cable between the vehicles, the speed of the hybrid underwater robotic complex is about 1 m/s in the joint motion mode and about 2 m/s in the towing mode. It is recommended to tow a remote-controlled underwater vehicle on a short cable length when the autonomous uninhabited underwater vehicle is submerged. In addition, it is necessary to adjust the cable length between the devices.
The structure of the Simulation Model of the Probabilistic Process of Forming the Accuracy of the Required Dimensions
Authors: Denchik A.I. , Kasenov A.Zh. , Galinovsky A.L. , Musina Zh.K. , Abishev K.K. , Tkachuk A.A.
Published: June 2022

A difficulty of ensuring the required accuracy of the product lies in the need to take into account many factors that affect the technological process of its manufacture and cause certain operational errors. Hence, it is advisable to use probabilistic and statistical methods, the versatility of which allows them to be used for solving a wide range of scientific and technical problems. The probabilistic approach to the forming the accuracy of the required product dimensions is a promising area of research, as it allows analyzing the general laws of the of the technological process kinetics, regardless of the physical and mechanical properties of materials, the shaping method, the features of the metal-cutting tool, etc. At the same time, the probabilistic approach allows the random nature of the influence of numerous factors on the formation of the accuracy of required dimensions to be integrally taken into account by determining the most probable result or probability value in a particular outcome of a particular test - a technological operation. The concept of a functionally significant technological perturbation of the process of forming a required size is used as the basis for solving the problem, leading to the appearance of a corresponding manufacturing error.
Prospects for Improving Centrifugal Pumps
Authors: Baybikov A.S.
Published: June 2022

The application of modern software systems and the exclusion of technological restrictions on the shape complexity can improve the energy, cavitation and mass characteristics of pumps. Plastic casings and wheels with metal frames provide increased rigidity and versatility of the units. Special coatings improve the smoothness and wear resistance of working surfaces. New shapes of axial and radial dynamic seals reduce volume losses during stabilization and the forces transmitted to the supports. The range of sensors built into the pump adjusting the mode and determining the continuous diagnostics of the pump condition increases.
Parents Experience in Providing Reproductive Health Education for Adolescent with Visual Disability in Yogyakarta
Authors: Kusumaningtyas Dewi , Wahyuni Budi , Hapsari Elsi Dwi
Published: June 2022

Background: Visibility impairment in children with visual disabilities affect their cognitive experiences, reproductive health problems and sexual abuse. One way to prevent negative experiences related to reproductive health and sexuality is to reproductive health education by parents as the closest person to the child. The purpose of this research is to get an idea how parent experience in providing reproductive health education to adolescents with visual disabilities in Yogyakarta. Method: This research is a qualitative research with phenomenology approach. The study was conducted from July to August 2017 in three schools, which are: SLB Negeri I Bantul, SLB Yaketunis and MTs LB Yaketunis Yogyakarta. Participans were selected by purposive sampling based on inclusion and exclusion criterion, and considered the maximum variation sampling. The participants were 10 visual disability parents (father and/or mother). The data was collected through interviews using semi-structured interview guidelines. Data were analyzed using Colaizzi method. Result of the research: Five themes are: 1) Reproductive health education is provided in accordance with the needs of children; 2) The parents have barriers in giving reproductive health education; 3) Reproductive health education in adolescent with visual disability is given by optimizing the sense of listening, touching and kissing  4) Religion and social norms become the basis of parent’s consideration in providing reproductive health education; 5) The visual disability conditions experience by parents will affect the education provided Conclusion: Reproductive health education is important since early age in adolescents with visual disability, by considering media and appropriate methode that is by optimizing the function of the sense of hearing, touch and smell.
Effect of Mirror Therapy on Phantom Pain Levels in Post Amputation Patient: a Literature Review
Authors: Sutawardana Jon Hafan , Siswoyo Siswoyo , Wantiyah Wantiyah , Kurdi Fahruddin , Murtaqib Murtaqib , Sari Dwi Ayu , Nistiandani Ana
Published: June 2022

Background: Phantom pain after amputation is ordinary. Phantom pain is challenging to treat, so it will last a long time which will cause depression and anxiety and reduce the quality of life. There are various treatment options: pharmacological (antidepressants, anesthetics) and non-pharmacological (acupuncture, hypnosis). However, there is still no proven effective therapy, so it is necessary to try a non-pharmacological therapy that is safe, cheap, and easy, namely mirror therapy. Purpose: This study aims to determine how the effect of mirror therapy on the phantom pain of post-amputation patients. Methods: Narrative literature review of a publication registered 2017-2021 on Pubmed, ProQuest, EBSCO, and Google Scholar. Search articles using the keywords" amputation," and " phantom pain," and "mirror therapy." This study uses inclusion criteria consisting of patients who experience phantom pain, research in the form of mirror therapy intervention, there is comparison, the study design uses a randomized controlled trial and case report, with results explaining the effect of mirror therapy in Indonesian or English, and indexed by SINTA or SCIMAGO. Results: 8 articles were included in the inclusion criteria. The majority of articles had a randomized controlled trial design of 7 articles and a case report of 1 article. Four articles discuss mirror therapy, and the other four articles discuss mirror therapy with other therapies. Respondents have an age range of 15-82 years, and most are male. Conclusion: Mirror therapy is recommended to be carried out routinely and according to procedures for post-amputation patients. It has been proven to reduce pain scales in patients before and after the intervention. Nurses can use mirror therapy in the client care process during the post-amputation rehabilitation process.
The Effectiveness of Topical Plant Oils Against Pain in Knee Osteoarthritis Patient
Authors: Saragih Betty Luinta , Masfuri Masfuri , Gayatri Dewi
Published: June 2022

The prevalence of knee osteoarthritis (OA) patients will increase along with the escalation of life expectancy. Complementary and alternative therapies like topical plant oils have been used to reduce pain in several countries. However, the effectiveness of this topical plant oil is not yet known, especially in patients with knee OA in Indonesia. This study aims to assess the effectiveness of topical plant oils on pain for knee OA patients through literatures review. The literature search was conducted using 5 electronic databases, namely PubMed, ScienceDirect, Emerald Insight and Cochrane (Central). The search for literature that matches the topic of literature review using PICO, after that a review is carried out using the PRISMA method. On initial search found 412 journals, then filtered according to the inclusion criteria, which are full text, English, 2015-2020 publications, and Randomized Control Trial design. The journals be obtained were filtered again by the title and the abstract then read the full text. There were 7 selected journals that matched to the inclusion criteria and research purposes after a critical assessment using the Joanna Briggs Institute (JBI) checklist for Randomized Controlled Trials. Topical plant oils are effective in reducing joint pain without side effects. These positive findings can be applied in Indonesia. Combination with other non-pharmacological therapies is suggested in future studies to increase the effectiveness of topical plant oils for knee OA patients in reducing joint pain.
Discursive practices of capoeira in Sergipe in the 19th century: knowledge, morals and narratives
Authors: Machado Tatiane Trindade , Feldens Dinamara Garcia
Published: June 2022

The work can be understood as a re-reading of the master's research in which we unveil the configurations of capoeira in Sergipe in the 19th century. In discussions about the origin of capoeira, a social practice that is present in more than 170 countries, few disagree about this movement having its birthplace in Brazilian lands. The objective of the research is to understand which discursive practices produce the knowledge racially and morally marked between segregation and the resistance of capoeira subjects. In this sense, we intend with this work to answer the following research problem: What are the discursive practices that produce knowledge that is racially and morally marked between segregation and the resistance of capoeira subjects? For the present research, the sociologists Norbert Elias and Antonio Gramsci and the philosopher Michel Foucault sought to mobilize the concepts of figuration, network of interdependence and hegemony, and the discourses on the social practice of capoeira, respectively.
Ali Şîr Nevâyî’nin Sedd-i İskenderî’sinden Hareketle Klasik Metinlerin Yeniden Yazılmasının Gerekliliği Üzerine Düşünceler
Authors: ATİK GÜRBÜZ İncinur
Published: June 2022

Bu çalışma, temelde “Türk tarihinin klasik şahsiyetleri ve eserleri günümüz insanına nasıl tanıtılabilir? Bunun için kimler, hangi eser(ler) ve eser(ler)deki hangi unsurlar, motifler ya da anlatılar kullanılabilir? Bu süreçte hangi yöntemlerden faydalanılabilir?” sorularına cevap aramak üzere hazırlanmıştır. Uzun vadede bütün tarihî metinlerin yeniden-yazılması gerektiğini düşünmekle birlikte, kültür taşıyıcılığı potansiyeline sahip olan klasikleşmiş şahsiyetlerin ve eserlerin öncelenmesi gerektiği kanaatindeyiz. Bu süreçte kaynak metinler belirlendikten sonra asıl önemli nokta, bu metinlerin günümüz insanının haz alabileceği bir forma dönüştürülmesidir. Böyle bir dönüşüm için modern metin eleştiri yöntemlerinden biri olan “yeniden-yazma”nın imkânlarından yararlanılabileceğini düşünüyoruz. Bu çalışmada, yeniden-yazılması “gerektiğini” düşündüğümüz şahıs/eser örneği olarak sahip olduğu özellikler dolayısıyla Alî Şîr Nevâyî ve onun Sedd-i İskenderî adlı eseri seçilmiştir. Çalışmanın başında yeniden-yazma yöntemi hakkında kısaca bilgi verilerek klasik metinlerin niçin yeniden-yazılması gerektiği tartışılacaktır. Sonrasında yeniden-yazılması için neden Alî Şîr Nevâyî’yi ve onun Sedd-i İskenderî’sini önerdiğimize ilişkin değerlendirmeler yapılacaktır. Daha sonra kastettiğimiz türde bir yeniden-yazma sürecinin nasıl bir organizasyon üzerinden yürütülebileceği sorgulanacaktır. Son olarak da Sedd-i İskenderî’nin “olası” bir yeniden-yazımında vurgulanması gerektiğini düşündüğümüz unsurlara örnekler verilecektir.
Shattering Dietary Taboos in Post-Pandemic Era: Human-Animal Interaction in J. M. Coetzee’s Elizabeth Costello
Authors: ERDAL Baturay
Published: June 2022

Many conspiracy theories and worst-case scenarios have been produced about the COVID-19 pandemic. With a reductionist approach, this new coronavirus disease outbreak has been regrettably confined to the simple matter that humans are exposed to viral pathogens of certain wild animals. However, the global reasons and outcomes of the present outbreak should not simply be correlated with the physiologies of a group of animals but with human activities subject to wanton consumption, interference with living spaces, intense commercialization and, particularly, dietary habits. Thus, reconceptualizing pandemics as a multidimensional “ecological crisis” posing a threat to the future of human and nonhuman beings rather than a “disease” endangering human welfare seems to become the sole prerequisite for a significant policy shift in the relationship between humans and animals. With this in mind, the eponymous protagonist of the novel, Elizabeth Costello, a vegetarian like her creator, gives the traces of an ecological philosophy which reinforces the notion that it is not the sheer scientific productivity driven by the rationalization but the reconsideration of animal-human interactions that can prevent post-pandemic era from recurring outbreaks. In the novel, through her understanding of environmental ethics, J. M. Coetzee’s vegetarian and writer protagonist provides discussions that help rethinking literature as one of the guiding disciplines that can offer new insights into the natural habitat of animals. This study intends to handle how Coetzee’s thoughts on vegetarianism and human-animal interactions can become an ethical model for the future world in dire need of a post-pandemic paradigm shift.
Abdurrahman Süreyya’nın Ta’lîkât-I Belâgat-I Osmâniyye Adlı Eserinde Dil ve Edebiyat Terminolojisi
Authors: GÜNEŞ Bahadır
Published: June 2022

Belagat, ifadenin muhatabın durumunu, yer ve zamana uygunluğunu, doğruluk ve güzelliğini belirleyen kuralları içeren tarihî geçmişi eski bir disiplindir. Kendi içinde meani, beyan, bedii, fesahat gibi bölümleri olan belagat, aynı zamanda bu bölümlerin alt kollarını meydana getiren çok sayıda söz kuralına sahiptir. Genellikle söz sanatları ekseninde ve manzum metinler aracılığıyla karşılaşılan belagat, aslında genel anlamda sözün düzenini sağlamaya çalışan kuralların bütününü içerir. Türk edebiyatında özellikle klasik Türk edebiyatı sahasının araştırma alanı olarak öne çıkan belagat, içerdiği zengin terminolojik veriler ve söz temelinde dil ile münasebeti sebebiyle aynı zamanda dil bilimini de ilgilendirir. Belagatin kurallar koyan bir disiplin olması, birtakım yaklaşım farklarından ötürü bazı eksiklik veya kusurların bu disiplin etrafında tartışma konusu olmasına yol açmış, Türk edebiyatı metinlerinde belagat kurallarının uygulanmasıyla ilgili bazı tartışmalar meydana gelmiştir. Bu tartışmalardan biri de Ahmed Cevdet Paşa’nın Belâgat-ı Osmâniyye adlı eserinin Abdurrahman Süreyya tarafından kaleme alınan ve bu eseri çeşitli yönleriyle tenkit eden Ta’lîkât-ı Belâgat-ı Osmâniyye adlı risalenin yazılmasıyla oluşmuştur. Belâgat-ı Osmâniyye’deki aksaklıkları tespit eden ve bu esere yönelik tenkitler içeren Ta’lîkât-ı Belâgat-ı Osmâniyye’de dil ve edebiyat ağırlıklı terminolojik veriler öne çıkmaktadır. Bu çalışmada, Abdurrahman Süreyya’nın yazdığı Ta’lîkât-ı Belâgat-ı Osmâniyye adlı risalede tespit edilen dil ve edebiyat terimleri anlamlarıyla birlikte alfabetik olarak düzenlenerek söz konusu eserin dil ve edebiyat terminolojisi açısından sahip olduğu malzeme ortaya konmuştur.
13. Yüzyılda Anadolu ve Kafkasya: Mkhargrdzeli Sülalesine Bağlı Mimaride Papa I. Sylvester Figürü
Authors: ATAÇ Nergis
Published: June 2022

Mkhargrdzeli sülalesine bağlı mimari; Orta Çağ Anadolu ve Kafkasya’nın dinî, askerî, siyasi ve sosyal ortamına ışık tutmaktadır. Kars Ani Tigran Honents’in Aziz Gregorios Kilisesi (1215-1225) ve Ermenistan Akhtala Kilisesi’nde (1205-1213) kilise babalarından Roma Piskoposu I. Sylvester’ın (314-335) resmedilmesi buna örnektir. Bir Roma piskoposunun bölgedeki bilinen sadece iki örneğinin, Mkhargrdzeli ailesiyle ilgili yapılarda yer alması açıklanmalıdır. Roma piskoposu bu iki kilisenin en kutsal duvarında neden resmedilmiştir? Bir yandan Bizans’tan ümidini kesen bölgenin Hıristiyan devletleri, güçlenen Müslümanlara karşı sözde Hıristiyan Prester John’un (David) beklentisinin rivayet olduğunun farkına varmış, diğer yandan Batı Hıristiyanları doğuda emellerini gerçekleştirmek için destek arayışına girmiştir. Mkhargrdzeli sülalesine bağlı mimari de bu bağlamda dönemin mücadelelerini ve anlaşmalarını aydınlatmaktadır. Elde edilen verilerden yola çıkarak I. Sylvester figürünün Mkhargrdzeli sülalesinin kiliselerinde yer alması sorusuna ve duvar görsellerinin tarihlendirilmesine yeni öneriler getirilmiş, duvar görsellerinin bölgede gelişen siyasi ve dinî olaylarla bağı ortaya konulmuştur.
II. Meşrutiyet Döneminde At Neslinin Islahına Yönelik Bir Örgütlenme Örneği: Islah-ı Nesl-i Feres Cemiyeti
Authors: KURNAZ ŞAHİN Feyza
Published: June 2022

Bu makale, II. Meşrutiyet sonrasında 11 Nisan 1912’de iyi cins at yetiştirmek, at yarışları düzenlemek, biniciliği geliştirmek amacıyla padişahın himayesinde kurulan Islah-ı Nesl-i Feres Cemiyeti’nin faaliyetlerine odaklanmıştır. Osmanlı Devleti’nde atın çekim gücü ve taşıma kapasitesi, tarımsal ekonomi ve savunma açısından hayati bir öneme sahipti. Ancak XIX. yüzyılın ilk yarısından itibaren ihtiyaçlara göre at neslinin ıslahı ve çoğaltılması hususunda bazı sıkıntılar mevcuttu. Zira tımar sisteminin bozulması ve Yeniçeri Ocağı’nın kaldırılması at yetiştiriciliğine zarar vermişti. Askeri ve tarımsal ihtiyaçları karşılamak için modern haralar kurulsa da bu çaba yeterli olmadı. Arz sıkıntısı ve satın alma düzenlemeleri, Osmanlı ordusunun lojistiğini tehdit eder boyuta ulaştı. Bu nedenle Osmanlı Hükümeti, Avrupalı devletlerde olduğu gibi nitelikli atlarda yerli bir pazarın yaratılmasına yönelik politikalar üretmeye başladı. Hükümet, at cinsinin ıslahını sağlayan vasıtalardan birisi olan at yarışlarını düzenlemek için 1912’de Islah-ı Nesl-i Feres Cemiyeti’ni kurdu.
Features of the course of acute pyelonephritis in children with an experience of a new coronavirus infection (COVID-19)
Authors: Eremeeva A. V. , Dlin V. V.
Published: June 2022

Purpose. To determine the clinical and laboratory features of the course of acute pyelonephritis in children with a history of COVID-19 and to determine the risk of developing chronic kidney disease.

Material and methods. The main cohort consisted of 36 patients with the debut of acute pyelonephritis, who had previously suffered COVID-19, the average age was 7,5 years. The comparison group included 47 patients with the onset of acute pyelonephritis and a normal level of IgG antibodies to SARS-CoV-2, the average age was 7,0 years. Laboratory tests included full blood count and urinalysis, blood biochemistry, procalcitonin, urine microalbumin, urine creatinine, Zimnitsky urine test, bacteriological urine test, glomerular filtration rate, coagulogram, and Lipocalin-2 associated with neutrophil gelatinase (NGAL) in the urine.

Results. Patients with a history of COVID-19, at the onset of acute pyelonephritis, demonstrated a higher incidence of apostematous pyelonephritis, a higher degree of damage to the tubulointerstitial kidney tissue, a high frequency and a higher level of hematuria, proteinuria, hyperfiltration, hypostenuria, as well as a more significant increase in fibrinogen, CRP, procalcitonin, and uNGAL/Cr levels than children of the comparison group. It was shown that almost half of the children with acute pyelonephritis who had had COVID-19 retained urinary syndrome during examination 3–4 months after the onset of the disease.

Conclusion. Thus, long-term effects of the SARS-CoV-2 virus on the renal parenchyma were confirmed, even in asymptomatic children. The high level of uNGAL/Cr in children with acute pyelonephritis who had had COVID-19, which was almost 8 times higher than in the comparison group, reflects more pronounced damage to the tubulointerstitial kidney tissue. The risk of developing chronic kidney disease in this group was 3,5 times higher.
Blood pressure values during stress test in young elite athletes
Authors: Komoliatova V. N. , Besportochnii D. A. , Makarov L. M. , Kiseleva I. I. , Aksenova N. V.
Published: June 2022

It is known the blood pressure in children at rest depend on height, but this fact has not been considered during the exercise stress test.

Purpose. To determine the maximum value of blood pressure in young elite athletes, depending on the height and gender.

Characteristics of children and research methods. The study examined 2313 young elite athletes, members of the national teams of the Russian Federation in 40 sports disciplines (average age — (15,5 ± 1,4) years; 45% of young men). All subjects underwent PWC170 cycle ergometry, blood pressure was measured manually at each stage of testing, and its maxima were registered throughout the testing.

Results. The maximum blood pressure values in boys were higher than in girls: systolic blood pressure (195 ± 25) vs (175 ± 20) mmHg, p<0,001, diastolic blood pressure (80 ± 11) vs (80 ± 10) mmHg, p<0,05. There was relationship between the maximum value of the blood pressure on exercise and height (r=0,55; p<0,001). There were proposed normative tables for the maximum values of systolic blood pressure during exercise, depending on height.

Conclusion. In the young elite athletes, the maximum value of blood pressure during stress test depends not only on the gender, but also on the height. The maximum values of systolic blood pressure during exercise in tall young elite athletes can reach 250 mmHg in boys and 210 mmHg in girls.
Prediction of cardiovascular complications and progression of renal failure in pediatric patients with chronic kidney disease according to NKF-K/DOQI (2002) and KDIGO (2012) classifications
Authors: Savenkova N. D. , Grigorieva O. P.
Published: June 2022

Chronic kidney disease in pediatric and adult patients is an overarching global problem. Stratification of chronic kidney disease C1–5 severity by classifications of the National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI) (2002) and Kidney Disease: Improving Global Outcomes (KDIGO) (2012) carried out in pediatric patients over the age of 2 years old, taking into account the low glomerular filtration rate at the age of 0 to 2 years. Differences were found in the prognosis of cardiovascular complications and the progression of renal failure in adult patients with chronic kidney disease at stages С3а and C3b according to KDIGO (2012). The literature data demonstrate different risks of cardiovascular complications and progression of renal functions by stages of chronic kidney disease in accordance with the NKF-K/DOQI (2002) and KDIGO (2012) classifications in pediatric patients. The results indicate that children with chronic kidney disease in the pre-dialysis stages C2–4 form a high-risk group, while those on C4–5 dialysis form a group of very high risk of cardiovascular complications.
A clinical case of Streptococcus equi subsp. ruminatorum infection in a 9-year-old child
Authors: Yablonskaya K. P. , Keshishyan E. S. , Yelagin D. A. , Klimkova M. A. , Degtyareva A. V.
Published: June 2022

Streptococcus equi subsp. ruminatorum is a zoonotic disease that can cause serious morbidity in immunocompromised people. The first case of infection in human was described in 2007. We describe a case of infection in a 9-year-old child with a history of liver transplantation, who was hospitalized for differential diagnosis of high fever on continuous immunosuppressive therapy with Tacrolimus. The examination revealed an increase in the level of systemic inflammatory response markers, cholestasis and cytolysis syndrome markers, which indicated cholangitis. Acute graft rejection was excluded. Streptococcus. equi subsp. ruminatorum was identified in the patient’s blood cultures, which made it possible to diagnose a generalized zoonotic infection (the child was often in contact with horses) with a possible focus in the bile ducts, which required antibiotic therapy in combination with short-term, within 1 day, withdrawal and then a lower dose of immunosuppressive therapy (temporary adjustment of tacrolimus dosage). During the treatment, clinical and laboratory signs of the infectious process improved, and the functional state of the liver graft normalized. Therapy was stopped after negative blood cultures were obtained. This case confirms that S. equi subsp. ruminatorum can cause human disease. We emphasize the utility of molecular biological tests and MALDI-TOF mass spectrometry to be performed in patients with infections caused by group C streptococci.
Glycogen storage disease: PRKAG2 syndrome
Authors: Gandaeva L.  A.  , Kondakova O. B. , Basargina E. N. , Pushkov A. A. , Koloskova N. N. , Zharova O. P. , Barsky V. I. , Fisenko A. P. , Savostyanov K. V.
Published: June 2022

PRKAG2 syndrome is a rare genetic disease that isinherited in an autosomal dominant fashion and is caused by mutationsin the PRKAG2  gene. Clinical symptoms include early onset, ventricular preexcitation, cardiac hypertrophy, and progressive atrioventricular block.  The PRKAG2 syndrome is characterized by genetic heterogeneity, which makes early detection difficult; genophenotypic correlations  have been documented. In this article, we provide an overview of the literature data and experience from the cardiology department of the  National Medical Research Center for Children’s Health of the Russian Ministry of Health in the diagnosis and management of patients  with PRKAG2 syndrome, and present the clinical and genetic characteristics of the p.R302Q and p.H383R variants of the PRKAG2 gene.
COVID-19: Lessons from pediatric science and practice
Authors: Kharitonova L. A. , Grigoriev K. I.
Published: June 2022

The pandemic of a new severe infection, announced by the World Health Organization last year, is still spreading. To a certain extent, the epidemic has affected the pediatric population. Children have not been left out of the spread of COVID-19, and this applies even to newborns. The lecture presents summary data on the results of clinical observations both in the Tushino Children’s City Clinical Hospital in Moscow and scientific sources. A new disease is really new. This applies to its pathogenesis, diagnosis, treatment tactics with the use of modern medicines. For the first time, pediatricians are faced with the incredible situation where adults are more severely affected than children. It was noted that due to the limited period and scarce observations, all recommendations existing at this stage are temporary and undoubtedly subject to clarification. Most information regarding the impact of COVID-19 on a child is in clinical trials and is en route to be introduced into pediatric practice.
World Kidney Day: 2006–2022
Authors: Dlin V. V. , Savenkova N. D.
Published: June 2022

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Causes and prevention options for sarcopenia in children
Authors: Zavyalova A. N. , Khavkin A. I. , Novikova V. P.
Published: June 2022

Sarcopenia is a condition of progressive loss of muscle mass, moststudied in patients of senile age. Sarcopenia is described in children with oncological diseases, severe surgical pathology, in  the perioperative period with liver transplantation, immobility in children with cerebral palsy. Sarcopenia is associated with adverse disease outcomes. This article discusses the problem of sarcopenia using the  example of patients with stable dysmotility and posture. In addition to limited mobility, among the causes of  sarcopenia are impairment of the ability to eat, the availability of basic nutrients and vitamin D, and a change in the intestinal microbiome. Nutritional support combined with physical rehabilitation has been shown to be effective in reversing sarcopenia.