bluuebunny/crossref_metadata_2025 huggingface dataset:
Intervening in the Intergenerational Transmission of Trauma by Targeting Maternal Emotional Dysregulation With EMDR Therapy
Authors: Okawara Mii , Paulsen Sandra L.
Published: September 2018

Many studies have shown that the relationship between child and caregivers is critical for healthy development of the child’s brain function, and for intergenerational transmission of attachment. Here, we propose a useful eye movement desensitization and reprocessing (EMDR) target for treatment of maternal emotional dysregulation that can cause maltreatment of the child, with the goal of interrupting intergenerational transmission of attachment trauma. First, we use schematics to demonstrate a hypothetical model of the interaction between a child’s attachment behavior and a mother’s bonding behavior. This schematic shows that the child’s physiologic reaction activates or triggers the mother’s negative affect and somatic sensations in her limbic system and brain stem and that, in turn, evokes the mother’s maltreatment behavior. The negative affect and somatic sensation (maternal emotional dysregulation) are Dysfunctionally Stored Information (DSI) that was produced in the mother’s past experience. We propose that the mother’s negative affect and somatic sensations activated by the child’s behaviors can be useful targets for EMDR therapy based on this hypothetical model. Two Japanese case reports (mothers with 4-year-old daughters) are described to illustrate this application. Further discussion highlights the feature of Japanese cultural relationship and the dissociation, and the meaning and scope of targeting maternal emotional dysregulation with EMDR therapy.
Police Response to Domestic Violence: The Influence of Extralegal Factors on Arrest Decisions
Authors: Mele Marie
Published: September 2018

This study examines extralegal factors that predict arrest in domestic violence cases from one urban police department in the state of New Jersey. Initial analysis revealed that 40% of reported cases (N = 5,728) resulted in the suspect’s arrest. Bivariate analyses identified several predictors of arrest, including victim gender, victim/suspect relationship, cohabitation, and victim unemployment. At the multivariate level, cohabitation and victim unemployment were the strongest predictors of arrest. These findings are discussed in the context of a growing body of literature that examines the influence of extralegal factors on arrest decisions in domestic violence cases.
Pendidikan Islam dan Kelas Menengah Muslim Yogyakarta: Studi di SDIT Insan Utama Yogyakarta
Authors: Azizah Nur , Machali Imam
Published: September 2018

Masyarakat kelas menengah Muslim di Indonesia jumlahnya semakin meningkat seiring dengan pertumbuhan sekolah Islam terpadu. Mengetahui persepsi masyarakat tersebut terhadap sekolah Islam terpadu akan memberikan dampak yang positif terhadap perkembangan lembaga pendidikan Islam. Hasil penelitian menunjukkan bahwa masyarakat kelas menengah Muslim Yogyakarta di SDIT Insan Utama menganggap bahwa lembaga pendidikan Islam sangat penting dan sangat berperan dalam membentuk kepribadian anak yang Islami serta menambah pengetahuan mengenai ajaran-ajaran Islam. Sebanyak 77% masyarakat kelas menengah Muslim yang ada di SDIT Insan Utama adalah supportive parent, yaitu orang tua yang ideal yang memiliki high democratic dan high involvement terhadap anak. Berdasarkan kategori perilaku konsumen, sebanyak 55% kelas menengah Muslim di SDIT Insan Utama adalah universalist dan 45% conformist. Universalist adalah mereka yang memiliki nilai spiritual dan emosional yang tinggi terhadap suatu produk. Sedangkan conformist adalah mereka yang memiliki nilai spiritual yang tinggi tetapi tidak memperhatikan emotional/functional value dari suatu produk. Adapun faktor yang mempengaruhi persepsi mereka adalah faktor pengetahuan orang tua, latar belakang pendidikan, pengalaman, kemampuan, lokasi sekolah, lingkungan masyarakat, materi pelajaran dan budaya di lembaga pendidikan Islam.
Nanoplasmonic Sensing of CH3NH3PbI3 Perovskite Formation in Mimic of Solar Cell Photoelectrodes
Authors: Rajab Fahd M.
Published: September 2018

The formation of methylammonium lead iodide (CH3NH3PbI3) perovskite into mesoporous titania (TiO2) scaffold via a sequential deposition method is known to offer high quality films for good photovoltaic device performance. The growth reactions at the mesoporous TiO2 film depend on reactants concentration in the host matrix and the reaction activation energy. Here, we have used a NanoPlasmonic Sensing (NPS) approach with gold (Au) nanosensors to monitor the formation of CH3NH3PbI3 perovskite at the lower interface of 350 nm mesoporous TiO2, typical thickness used in a photovoltaic device. This technique provides time-resolved spectral shifts of the localized surface plasmon resonance at different operating temperatures and methylammonium iodide (CH3NH3I3) concentrations by recording changes in the local vicinity of the Au nanosensors at the mesoporous TiO2 film interface. Analytical studies included Ellipsometry, Scanning Electron Microscopy, and X-ray diffraction. The results show that perovskite conversion can be obtained at lower CH3NH3I3 concentrations if reaction activation energy is lowered. A significant finding is that the NPS response at 350 nm mesoporous TiO2 can widely change from red shifts to blue shifts depending on extent of conversion and morphology of perovskite formed at given reaction conditions.
Nanoplasmonic Sensing of CH3NH3PbI3 Perovskite Formation in Mimic of Solar Cell Photoelectrodes
Authors: Rajab Fahd
Published: September 2018

Hybrid metal-halide perovskites have emerged as leading class of semiconductors for photovoltaic devices with remarkable light harvesting efficiencies. The formation of methylammonium lead iodide (CH3NH3PbI3) perovskite into mesoporous titania (TiO2) scaffold by a sequential deposition technique is known to offer better control over the perovskite morphology. The growth reactions at the mesoporous TiO2 film depend on reactants concentration in the host matrix and the reaction activation energy. Here, we are characterizing formation of CH3NH3PbI3 perovskite in mimic solar cell photoelectrodes utilizing the developed NanoPlasmonic Sensing (NPS) approach. Based on dielectric changes at the TiO2 mesoporous film interface, the technique provides time-resolved spectral shifts of the localized surface plasmon resonance that varies widely depending on the different operating temperatures and methylammonium iodide (CH3NH3I) concentrations. Analytical studies included Ellipsometry, Scanning Electron Microscopy, and X-ray diffraction. The results show that perovskite conversion can be obtained at lower CH3NH3I concentrations if reaction activation energy is lowered. A significant finding is that the NPS response at 350 nm mesoporous TiO2 can widely change from red shifts to blue shifts depending on extent of conversion and morphology of perovskite formed at given reaction conditions.
Constraints on Lorentz Invariance Violation From Optical Polarimetry of Astrophysical Objects
Authors: Kislat Fabian
Published: September 2018

Theories of quantum gravity suggest that Lorentz invariance, the fundamental symmetry of the Theory of Relativity, may be broken at the Planck energy scale. While any deviation from conventional Physics must be minuscule in particular at attainable energies, this hypothesis motivates ever more sensitive tests of Lorentz symmetry. In the photon sector, astrophysical observations, in particular polarization measurements, are a very powerful tool because tiny deviations from Lorentz invariance will accumulate as photons propagate over cosmological distances. The Standard-Model Extension (SME) provides a theoretical framework in the form of an effective field theory that describes low-energy effects due to a more fundamental quantum gravity theory by adding additional terms to the Standard Model Lagrangian. These terms can be ordered by the mass dimension d of the corresponding operator and lead to a wavelength, polarization, and direction dependent phase velocity of light. In this paper, we analyze optical polarization measurements from 63 Active Galactic Nuclei (AGN) and Gamma-ray Bursts (GRBs) in order to search for Lorentz violating signals. We derive the first set limits on each of the 10 individual birefringent coefficients of the minimal SME with d = 4, with 95% confidence limits on the order of 10−34 on the dimensionless coefficients.
Atuação dos cirurgiões-dentistas na capacitação e desenvolvimento de ações de saúde bucal pelo agente comunitário
Authors: Terreri André Luiz Marçal , Baltazar Mariângela Monteiro de Melo , Berti Marina , Portinho Danielle , Lima Daniela Pereira
Published: September 2018

O presente estudo buscou analisar a percepção e atuação dos cirurgiões-dentistas inseridos na estratégia saúde da família do Município de Cascavel-PR, acerca da capacitação e desenvolvimento de ações de vigilância à saúde bucal pelo agente comunitário de saúde. A coleta dos dados foi realizada em todas as unidades de saúde da família que possuíam equipes de saúde bucal sendo utilizado um questionário estruturado, autoaplicável, composto por questões especialmente elaboradas para a pesquisa. Após a categorização, os dados coletados foram digitados em planilha eletrônica criada no software Epi Info, versão 3.5.1. O Teste Exato de Fisher com nível de significância de 5% foi utilizado para verificação de associação entre variáveis. Os resultados demonstraram pouca articulação entre cirurgiões-dentistas e agente comunitário de saúde na capacitação e desenvolvimento de ações de saúde bucal. Ter o titulo de especialista em odontologia em saúde coletiva não foi um fator significativo no treinamento e delegação de ações de saúde bucal. Mudanças no modelo de prestação dos serviços de saúde no município vão exigir a existência de um programa de educação permanente, que possibilite renovar e adquirir os conhecimentos de saúde bucal, para que os Agentes Comunitários de Saúde consigam atuar como atores na vigilância em saúde bucal.Descritores: Saúde Bucal; Agentes Comunitários de Saúde; Capacitação em Serviço.
Saúde bucal, fatores socioeconômicos e qualidade de vida de crianças de 12 anos de idade da cidade de Patos-PB
Authors: Queiroz Faldryene de Sousa , Costa Luciana Ellen Dantas , Silvestre Tuanny Lopes Alves
Published: September 2018

A cárie dentária tem sido discutida no Brasil e no mundo como um importante tema da saúde pública. O objetivo desse trabalho foi avaliar a associação entre cárie dentária, condições socioeconômicas e qualidade de vida de crianças de 12 anos de idade. O estudo transversal foi realizado com 266 crianças, de ambos os sexos, matriculadas em creches públicas e privadas da cidade de Patos/PB. Os aspectos relativos à qualidade de vida foram avaliados a partir do questionário Child Perceptions Questionnaire (CPQ11-14). Para avaliação das condições socioeconômicas das crianças foi utilizado um formulário contendo perguntas referentes à escolaridade do chefe da família, renda mensal familiar, número de componentes no domicílio, tipo de moradia e zona do domicílio. A prevalência de cárie dentária foi avaliada por meio do índice CPO-d e seus componentes. Observou-se que 42,9% das crianças de 12 anos tinham a doença cárie, apresentando CPO-d de 2,14, 73,5% do componente cariado. Houve associação significativa (p≤0,05) entre a cárie dentária e a qualidade de vida, bem como foi encontrada associação entre a presença de cárie e a renda, tipo de escola, escolaridade do chefe, quantidade de pessoas no domicílio e zona do domicílio. As ações de promoção e prevenção em saúde bucal devem estar cada vez mais presentes no dia a dia das crianças visando uma melhora na qualidade de vida.Descritores: Cárie Dentária; Qualidade de Vida; Condições Sociais; Saúde Bucal.
Biological Activities of Wild Asparagus (Asparagus acutifolius L.)
Authors: KASKA Arzu , DENİZ Nahide , MAMMADOV Ramazan
Published: September 2018

Asparagus acutifolius L. (wild asparagus)
is an edible plant species that is widely distributed throughout the
Mediterranean. This study was designed to investigate the phenolic compounds,
antioxidant, and cytotoxic activities of ethanol and water extracts of
different parts (fruits and leaves) of A.
acutifolius. The antioxidant activities of these extracts were analyzed
using scavenging methods (DPPH and ABTS scavenging activity), the
β-carotene/linoleic acid test system and the phosphomolybdenum method. Among
the evaluations of the ethanol and water extracts of the different parts of A. acutifolius, the ethanol extract of
the leaves was shown to have the highest amount of radical scavenging
activities (DPPH, 0.383 mg/mL and ABTS, 0.145 mg/mL). Each extract of A. acutifolius exhibited strong
antioxidant capacities with the β-carotene/Linoleic acid test system. For the
phosphomolybdenum method, the antioxidant capacity of the extracts was in the
range of 8.89-45.29 µg/mg and each extract exhibited high cytotoxic activities.
The results will provide additional information for future studies on the
biological activities of A. acutifolius, while
also helping us to understand the importance of this species.
Determinants of bank profitability: Islamic versus conventional banks
Authors: Alzoubi Tariq
Published: September 2018

This research analyzes the determinants of bank profitability by investigating the internal factors that affect the profitability of Islamic banks and conventional banks. It then compares the results from the two types in order to understand how they differ from each other. As previous researchers focus on either Islamic or conventional banks, this research will analyze both by comparing how they are each influenced by profitability factors. Few researches have attempted to compare the profitability of Islamic and conventional banks using a relatively small sample. This research uses a fixed effect panel data analysis on a large sample of 68 banks (42 Islamic and 26 conventional banks) from 13 MENA countries, covering the period of 2006 until 2016. Using several variables, including bank size, equities to assets, loans to assets, deposits to assets, cash to assets and securities to assets, the results show that bank size, equities to assets and deposits to assets have a significant positive effect on Islamic banks’ profitability, while they have a significant negative effect on conventional banks’ profitability; loans to assets and cash to assets have no effect on bank profitability for either Islamic or conventional banks; and securities to assets has a significant negative effect on Islamic banks’ profitability, while it has a significant positive effect on conventional banks’ profitability. The results also show that bank size, equities to assets, deposits to assets and cash to assets contribute more to Islamic banks’ profitability compared to conventional banks, while loans to assets and securities to assets contribute more to conventional banks’ profitability compared to Islamic banks.
Doğu Anadolu’nun Güneyinden Toplanan Fasulye (Phaseolus vulgaris L.) Gen Kaynaklarının Çiçek ve Tohum Özelliklerinin Belirlenmesi
Authors: ÇİRKA Mustafa , ÇİFTÇİ Vahdettin
Published: September 2018

Doğu Anadolu Bölgesi’nin güneyinde (Malatya, Muş, Tunceli, Van, Elâzığ, Hakkâri, Bitlis ve Bingöl) tazetüketime uygun fasulye gen kaynaklarının toplanması, çiçek ve tohum özelliklerinin belirlenmesi ve ümitvar hatlarınseçilmesi amacıyla çalışma, 2009 ile 2011 yılları arasında yürütülmüştür. Çalışmada standart çeşitlerden HelindaGold ve 4F-89 (sırık taze çeşit), Yalova-5 ve Yalova-17 (bodur taze çeşit) kontrol çeşitler olarak kullanılmıştır.2009 yılında toplanan 414 fasulye genotipinden 2010 yılında 378 genotip çimlendirilmiş, tartılı derecelendirmesonucu 420 ve üzeri puan alan 25 fasulye genotipi ümitvar olarak belirlenmiştir. Denemenin 25 genotip üzerindeyürütülen ikinci yılında (2011), 420 ve üzeri puan alan 13 ümitvar hat (11 sırık ve 2 bodur) çalışmada tespitedilmiştir. Bu çalışmayla standart çeşitler ile ümitvar hatlar arasında farklılıkların olduğu saptanmıştır.
Ticari Olarak Satın Alınan Nar Suyunun Antibakteriyal ve Bazı Antibiyotiklerle Sinerjistik Etkisi
Authors: ARI Merve , ERBİL Nurcan
Published: September 2018

Nar suyu günlük hayatamızda tükettiğimiz bir meyve suyu olup, narın sağlık açısından oldukça faydalıolduğu bilinmektedir. Bu çalışmada ticari olarak satın alınarak tüketilen nar sularının farklı Gram (+) ve Gram (-)bakteriler üzerinde oluşturduğu antibakteryel aktivitenin ve antibiyotiklerle beraber kullanıldığında oluşabileceksinerjistik etkinin belirlenmesi amaçlanmıştır. Bu amaçla ticari olarak satın alınan “meySu” markalı nar suyukullanılmıştır. Elde edilen sonuçlar neticesinde tek başına Ampisilin’in 7.64-9.23 mm; Gentamisin’in 22.26-22.98mm; nar suyunun ise 19.07-20.14 mm arasında zon çapı meydana getirdiği görülmüştür. Bakıldığında tek başınanar suyunun Ampisilin’den daha yüksek oranda antibakteriyal aktivite sergilediği görülmektedir. Nar suyu veAmpicillin beraber uygulandığında 20.11-21.14 mm araasında, nar suyu ve Gentamisin birlikte uygulandığında ise26.36-28.94 mm araasında zon çapı oluşturduğu görülmektedir. Bu sonuçlar nar suyunun Gentamisin ile daha fazlaolmak üzere her iki antibiyotik ile sinerjistik etki gösterdiğini ortaya koymaktadır. Çalışma sonucunda elde edilenveriler, nar suyunun test bakterilerine karşı oldukça iyi düzeyde antibakteriyal aktivite sergilediğini göstermektedir.Ayrıca; nar suyunun test edilen antibiyotiklerle beraber kullanıldığında sinerjistik etki yaratması da ayrıca biröneme sahiptir.
Hindi Karaciğerinden NADPH-Sitokrom P450 Redüktaz’ın Saflaştırılması, Karakterizasyonu ve Bazı Metal İyonlarının Enzim Aktivitesi Üzerindeki Etkileri
Authors: AKKEMİK Ebru , ÇİFTÇİ Mehmet
Published: September 2018

NADPH-Sitokrom P450 redüktaz (CPR) enzimi, detoksifikasyon metabolizmasında elektron transferinikatalizleyen anahtar bir enzimdir. Bu çalışmada, hindi karaciğer mikrozomlarından CPR enziminin saflaştırılmasıiçin iki yöntem kullanılmıştır. Birinci yöntemde, CPR enzimi ~114 saflaştırma katsayısıyla ve ~%23 verimle2’, 5’-ADP Sefaroz 4B afinite kolonu kullanılarak saflaştırılmıştır. İkinci yöntemde, CPR, DE-52 selüloz anyondeğişim kolonu ve 2’, 5’-ADP Sefaroz 4B afinite kolonu kullanılarak, ~124’lük saflaştırma katsayısı ve %8verimle saflaştırılmıştır. Enzim saflığı her iki yöntemde de SDS-PAGE ile kontrol edilmiştir. Saflaştırılmış enziminkarakteristik kinetik özellikleri belirlenmiştir. Bazı metal iyonlarının saflaştırılmış CPR enzim aktivitesi üzerindekietkileri in vitro şartlarda araştırılmıştır. Ag+, Hg2+ ve Cu2+ metal iyonlarının CPR enzim aktivitesi üzerinde inhibisyonetkisi gösterdiği tespit edilmiştir.
Inter-ply Hibrit Kompozit Yapılarda Elyaf Diziliş Sıralamasının Mekanik ve Dinamik Özelliklere Etkisi
Authors: AYDIN Muhammet Raci , ACAR Volkan , YAPICI Furkan , YILDIZ Kaan , TOPCU Muhammed Vefa , GÜNDOĞDU Ömer
Published: September 2018

Son yıllarda geliştirilen yeni üretim metotları ile tabakalı kompozit yapıların kullanım alanları dikkatedeğer bir şekilde artmıştır. Bu yapıların kullanım performanslarını arttırmak amacıyla farklı tekil kumaşlar,farklı diziliş sıraları ile aynı kompozit yapıda kullanılarak hibrit kompozit yapılar elde edilmiştir. Tabakalı hibritkompozit yapıların mekanik özellikleri ile ilgili birçok araştırma yapılmışken dinamik özellikleri ile ilgili yapılanaraştırmalar henüz yeterli değildir. Bu çalışma kapsamında; tekil cam (C) ve tekil karbon (K) elyaflar kullanılarakVARTM (Vakum Destekli Reçine Transfer Kalıplama) yöntemi ile 4 tabakalı, 4 farklı diziliş sırasına sahipnumunelerin üretimi gerçekleştirilmiştir. Bu numuneler; sade cam (C4), sade karbon (K4) olmak üzere iki tekilkompozit yapı ve bu iki elyaf türünün aynı yapı içerisinde simetrik olarak farklı diziliş sıralarıyla kullanılmasıylaelde edilen iki farklı hibrit kompozit yapıdan (KCCK ve CKKC) oluşmaktadır. Üretilen kompozit levhalardan,ilgili ASTM standartlarına göre üç nokta eğilme, çekme ve titreşim testleri için gerekli olan numuneler kesilerekelde edilmiştir. Üç nokta eğilme testleri yapılarak numunelerin maksimum eğilme dayanımları ve çekme testleriyapılarak numunelerin elastisite modülleri belirlenmiştir. Ayrıca ankastre-serbest sınır şartında serbest titreşimanalizleri yapılarak doğal frekans ve sönüm oranı değerleri tespit edilmiştir. Elde edilen sonuçlar ile interply hibritkompozit yapılarda diziliş sırasının maksimum eğilme dayanımı, elastisite modülü ve titreşim özelliklerine etkisiincelenmiştir.
Dual-Variable Functions on Time Scale
Authors: SAMANCI Hatice Kuşak
Published: September 2018

In this paper, we study the concept of dual-variable functions parameterized by the product oftwo arbitrary time scales. Firstly, we give some preliminaries of the dual numbers and dual-variable functions.Secondly, we introduce some properties of the time scales. In the main result, we investigate the limit, derivative,partial differentiation and Cauchy-Riemann equation of the dual-variable functions on time scales.
The influence of dissolved oxygen on partial nitritation/anammox performance and microbial community of the 200,000 m3/d activated sludge process at the Changi water reclamation plant (2011 to 2016)
Authors: Cao Yeshi , Kwok Bee Hong , van Loosdrecht Mark C. M. , Daigger Glen , Png Hui Yi , Long Wah Yuen , Eng Ooi Kian
Published: September 2018

Mainstream partial nitritation/anammox (PN/A), coupled with excess biological phosphorus removal, in a 200,000 m3/d step-feed activated sludge process (Train 2) in the Changi Water Reclamation Plant (WRP), Singapore, has been studied and reported. This paper presents an overview of process performance and the microbial community during the period from 2011 to 2016. The site data showed that, along with the reduction of dissolved oxygen (DO) from 1.7 to 1.0 mg O2/L in the aeration zones, the concentrations of ammonium and nitrate of the final effluent increased, while nitrite decreased, resulting in an increase of 2.4 mg N/L of total inorganic nitrogen. Autotrophic nitrogen removal was higher than heterotrophic biological nitrogen removal under higher DO concentration conditions, but decreased under low DO operating condition. These macro-scale changes were caused by shifts of the nitrogen-converting microbial community. The ammonia oxidizing bacteria (AOB) population abundance was reduced by 30 times, while the nitrite oxidizing bacteria (NOB) population abundance and specific activity increased significantly with a shift of dominant genus from Nitrobacter to Nitrospira. The ratio of AOB and NOB specific activities were reduced from 12.8 to 1.6, and the ex situ nitrite accumulation ratio reduced from 76% to 29%. Changes in the microbial community and overall process performance illustrated that, compared to the excellent NOB suppression under high DO conditions, NOB were more active after the DO concentration reduction despite still being partly suppressed. This case study demonstrated, for the first time, the influence of DO reduction on the nitrogen conversion microbial community and PN/A process performance for a suspended growth system. Its relevance to biofilm and hybrid PN/A processes is also discussed.
Microalgae as biological treatment for municipal wastewater – effects on the sludge handling in a treatment plant
Authors: Olsson J. , Schwede S. , Nehrenheim E. , Thorin E.
Published: September 2018

A mix of microalgae and bacteria was cultivated on pre-sedimented municipal wastewater in a continuous operated microalgae-activated sludge process. The excess material from the process was co-digested with primary sludge in mesophilic and thermophilic conditions in semi-continuous mode (5 L digesters). Two reference digesters (5 L digesters) fed with waste-activated sludge (WAS) and primary sludge were operated in parallel. The methane yield was slightly reduced (≈10%) when the microalgal-bacterial substrate was used in place of the WAS in thermophilic conditions, but remained approximately similar in mesophilic conditions. The uptake of heavy metals was higher with the microalgal-bacterial substrate in comparison to the WAS, which resulted in higher levels of heavy metals in the digestates. The addition of microalgal-bacterial substrate enhanced the dewaterability in thermophilic conditions. Finally, excess heat can be recovered in both mesophilic and thermophilic conditions.
La economía de San Luis Potosí en las dos últimas décadas. Algunas referencias empíricas sobre el periodo 1990-2010
Authors: Martinez Melgarejo Milton Jesús
Published: September 2018

La investigación tiene como objetivo analizar la evolución de la economía del estado de San Luis Potosí de 1990 a 2010. Se plantea la hipótesis de que el intenso proceso de integración económica del estado, mediante la captación de inversión extranjera directa de empresas manufactureras, ha intensificado la desigualdad regional en términos del producto interno bruto y de los niveles de bienestar. Para ello, se describirá y analizará la evolución de la economía del estado de San Luis Potosí en el contexto de los cambios permanentes de la economía mexicana en la última mitad del siglo XX, y se hará una revisión de los principales indicadores económicos, demográficos y de bienestar del estado de 1993 a 2010. Los resultados altamente contrastantes en los niveles de desarrollo y de competitividad en las regiones del estado de San Luis Potosí plantean la reflexión sobre la pertinencia de modificar la estrategia de desarrollo regional actual. Las conclusiones del artículo se construyen a partir del enfoque de la economía descriptiva, en el que se observan fenómenos económicos de desigualdad y desequilibrio social. No obstante, desde el enfoque de la economía normativa, se proponen algunas reflexiones que transitan por la política económica para modificar las estrategias de desarrollo regional.
La construcción de la historia ambiental en América
Authors: Rivera Castañeda Patricia , Chávez Ramírez Refugio
Published: September 2018

El objetivo del artículo es analizar los detonantes, la diversificación, el enriquecimiento y la complejización de la historia ambiental en América como un constructo social. Para ello, se realiza una caracterización de los estudios seleccionados, desde una posición analítica hombre-naturaleza, identificando su escala de análisis. Como resultado, se apunta que el avance de la historia ambiental ha consistido en considerar la naturaleza desde una perspectiva amplia, en la que las crisis sociales explican las crisis ambientales. En relación con las limitaciones, se menciona que, por ser un campo en discusión, existe una variabilidad inmensa, pues el papel de la naturaleza está determinado por la posición ética de cada autor. La originalidad del presente trabajo consiste en profundizar en el conocimiento sobre la historiografía ambiental en América al efectuar una aportación empírica de caracterización. Se concluye que la historia ambiental, como disciplina, permite determinar qué es sustancial en la relación sociedad-naturaleza en diferentes periodos.
Los talleres de la vida de Ricardo Elizondo Elizondo
Authors: Martínez Vela Marlon
Published: September 2018

Se trata de una breve reseña sobre la novela póstuma del escritor neoleonés Ricardo Elizondo Elizondo, ya que no hay un texto dedicado a esta obra. En este breve texto se destacan algunas de sus carcaterísticas composicionales, así como las temáticas que se vinculan a otras piezas del mismo autor. También destacan el papel de las mujeres, la muerte y la literatura de tradición oral.
A saúde e o Sistema Único de Saúde nos bastidores da imprensa: o que os jornalistas têm a nos dizer?
Authors: Da Silva Thalita Mascarelo , Prado Heloisa Vieira , Emerich Tatiana Breder , Cavaca Aline Guio , Oliveira Adauto Emmerich , Gentilli Victor
Published: September 2018

Health and the Unified Health System behind the scenes: what do journalists have to tell us?
Observatório de Saúde na Mídia - Regional Espírito Santo: relato de uma experiência interdisciplinar em Saúde Coletiva
Authors: Cavaca Sthefany Duhz , Miliorelli Cecília Ribeiro , Figueiredo Conti Maria Fernanda , Dos Santos Vinicius Nery , Coelho Júnior Abeil , Emerich Tatiana Breder , Cavaca Aline Guio
Published: September 2018

Observatories of Health in the Media – Espírito Santo Regional: an interdisciplinary experience report in Public Health
The Role of Lipids and Membranes in the Pathogenesis of Alzheimer's Disease: A Comprehensive View
Authors: Penke Botond , Paragi Gábor , Gera János , Berkecz Róbert , Kovács Zsolt , Crul Tim , VÍgh László
Published: September 2018

Lipids participate in Amyloid Precursor Protein (APP) trafficking and processing - important
factors in the initiation of Alzheimer’s disease (AD) pathogenesis and influence the formation of neurotoxic
β-amyloid (Aβ) peptides. An important risk factor, the presence of ApoE4 protein in AD brain
cells binds the lipids to AD. In addition, lipid signaling pathways have a crucial role in the cellular
homeostasis and depend on specific protein-lipid interactions. The current review focuses on pathological
alterations of membrane lipids (cholesterol, glycerophospholipids, sphingolipids) and lipid metabolism
in AD and provides insight in the current understanding of biological membranes, their lipid structures
and functions, as well as their role as potential therapeutic targets. Novel methods for studying the
membrane structure and lipid composition will be reviewed in a broad sense whereas the use of lipid
biomarkers for early diagnosis of AD will be shortly summarized. Interactions of Aβ peptides with the
cell membrane and different subcellular organelles are reviewed. Next, the details of the most important
lipid signaling pathways, including the role of the plasma membrane as stress sensor and its therapeutic
applications are given. 4-hydroxy-2-nonenal may play a special role in the initiation of the pathogenesis
of AD and thus the “calpain-cathepsin hypothesis” of AD is highlighted. Finally, the most important
lipid dietary factors and their possible use and efficacy in the prevention of AD are discussed.
Proteomic Analysis of Cerebrospinal Fluid: A Search for Biomarkers of Neuropsychiatric Systemic Lupus Erythematosus
Authors: Pedroza-Díaz Johanna , Chavarria Tania Paola Luján , Vahos Carlos Horacio Muñoz , Hernández Ramírez Diego Francisco , Olivares-Martínez Elizabeth , Vásquez Gloria , Llorente Luis , Fragoso-Loyo Hilda , Röthlisberger Sarah , Ortiz Reyes Blanca Lucía
Published: September 2018

Background:

Neuropsychiatric systemic lupus erythematosus or NPSLE, as its name suggests, refers to the neurological and psychiatric manifestations of Systemic Lupus Erythematosus (SLE). In clinical practice, it is often difficult to reach an accurate diagnosis, as this disease presents differently in different patients, and the available diagnostic tests are often not specific enough.

Objectives:

The aim of this study was to search for proteomic biomarkers in cerebrospinal fluid that could be proposed as diagnostic aids for this disease.

Methods:

The proteomic profile of cerebrospinal fluid samples of 19 patients with NPSLE, 12 patients with SLE and no neuropsychiatric manifestation (SLEnoNP), 6 patients with neuropsychiatric symptoms but no SLE (NPnoSLE), 5 with Other Autoimmune Disorders without neuropsychiatric manifestations (OADs), and 4 Healthy Controls (HC), were obtained by two-dimensional gel electrophoresis and compared using ImageMaster Platinum 7.0 software.

Results:

The comparative analysis of the different study groups revealed three proteins of interest that were consistently over-expressed in NPSLE patients. These were identified by mass spectrometry as albumin (spot 16), haptoglobin (spot 160), and beta-2 microglobulin (spot 161).

Conclusion:

This work is one of the few proteomic studies of NPSLE that uses cerebrospinal fluid as the biological sample. Albumin has previously been proposed as a potential biomarker of rheumatoid arthritis and SLE, which is coherent with these results; but this is the first report of haptoglobin and beta-2 microglobulin in NPSLE, although haptoglobin has been associated with increased antibody production and beta-2 microglobulin with lupus nephritis.
Melanoma Skin Cancer Detection based on Image Processing
Authors: Zghal Nadia Smaoui , Derbel Nabil
Published: September 2018

Background:

Skin cancer is one of the most common forms of cancers among
humans. It can be classified as non-melanoma and melanoma. Although melanomas are less
common than non-melanomas, the former is the most common cause of mortality. Therefore,
it becomes necessary to develop a Computer-aided Diagnosis (CAD) aiming to detect
this kind of lesion and enable the diagnosis of the disease at an early stage in order to augment
the patient’s survival likelihood.

Aims:

This paper aims to develop a simple method capable of detecting and classifying skin
lesions using dermoscopy images based on ABCD rules.

Methods:

The proposed approach follows four steps. 1) The preprocessing stage consists of
filtering and contrast enhancing algorithms. 2) The segmentation stage aims at detecting the
lesion. 3) The feature extraction stage based on the calculation of the four parameters which
are asymmetry, border irregularity, color and diameter. 4) The classification stage based on
the summation of the four extracted parameters multiplied by their weights yields the total
dermoscopy value (TDV); hence, the lesion is classified into benign, suspicious or malignant.
The proposed approach is implemented in the MATLAB environment and the experiment
is based on PH2 database containing suspicious melanoma skin cancer.

Results and Conclusion:

Based on the experiment, the accuracy of the developed approach
is 90%, which reflects its reliability.
ZnO Nanoparticles Catalyst in the Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2
Authors: Dawood Dina H. , Abbas Eman M.H. , Farghaly Thoraya A. , Ali Mamdouh M. , Ibrahim Mohammed F.
Published: September 2018

Background:

Pyrimidines emerged as a remarkable class of heterocyclic compounds
that have reinforced the pharmaceutical chemistry with various bioactive antitumor agents.
Moreover, pyrimidine scaffold displayed VEGFR-2 inhibitory activity. Also, nano-sized catalysts
are used in organic reactions in order to speed up the catalytic process.

Objective:

We were interested herein to synthesize a new series of fused pyrimidines using
ZnO(NPs) to investigate their antitumor efficiency against breast MCF7 cancer and their VEGFR-
2 inhibition properties.

Method:

A simple and efficient method for the synthesis of fused pyrimidines was developed using
zinc oxide nanoparticles ZnO(NPs) in refluxing ethanol.

Results:

The proposed structures of all new fused pyrimidines are in agreement with their spectral
data. Antitumor evaluation of newly fused pyrimidine derivatives against breast MCF-7 cancer
was performed. It was apparent that the 2-phenylpyrazolo[1,5-a]pyrimidine derivatives 9a (IC50 =
9.12±1.16 µg/ml), 9c (IC50 = 9.10±1.07 µg/ml) and 9d (IC50 = 9.60±1.22 &µg/ml) exhibited equipotent
antitumor activity as Tamoxifen (IC50 = 9.11±0.90 &µg/ml). Also, the inhibitory activity of
the novel fused pyrimidine derivatives on VEGFR-2 as well as Tamoxifen was determined using
breast cancer cell line MCF-7. The data was obvious that 2-phenylpyrazolo[1,5-a]pyrimidine derivatives
9a, 9c and 9d exhibited noticeable VEGFR-2 inhibitory effect with % inhibition ranging
from 80-84 % versus Tamoxifen 93.5%.

Conclusion:

We succeeded in this context to synthesize new fused pyrimidines using ZnO(NPs)
as anti-breast cancer agents targeting VEGFR-2.
RETRACTED: Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate
Authors: Lu D.Y. , Lu T.R. , Xu B
Published: September 2018

The article entitled “Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate”, by Lu
D.Y., Lu T.R., Xu B., Varki A., Huang M., Zhu H., Shen Y., Yarla N.S., has been retracted on the request of the co-authors Dr.
Ajit Varki, Ming Huang, Hong Zhu and Ying Shen available at: Anticancer Agents Med Chem. 2018; 18(14): 1952-1961.
http://www.eurekaselect.com/165282.

The Corresponding Author Dr. Da-Yong Lu has included the name of the co-author Dr. Ajit Varki, Dr. Nagendra Yarla, Ming
Huang, Hong Zhu and Ying Shen without their consent and the manuscript has been published in the journal Anti-Cancer Agents
in Medicinal Chemistry (ACAMC). Kindly see Bentham Science Policy on Article retraction at the link given below:

https://benthamscience.com/journals/anti-cancer-agents-in-medicinal-chemistry/editorial-policies/).

Submission of a manuscript to the respective journals implies that all authors have read and agreed to the content of the
Copyright Letter or the Terms and Conditions. As such this article represents a severe abuse of the scientific publishing system.
Bentham Science Publishers takes a very strong view on this matter and apologizes to the readers of the journal for any
inconvenience this may cause.
Thyroid Function in Egyptian Children with Sickle Cell Anemia in Correlation with Iron Load
Authors: Hagag Adel A. , El-Asy Hassan M. , Badraia Ibrahim M. , Hablas Nahed M. , El-Latif Amal Ezzat Abd
Published: September 2018

Background:

Sickle Cell Disease (SCD) is characterized by defective hemoglobin synthesis,
hemolytic anemia, frequent thrombosis and chronic organ damage including endocrine organs.

Aim: To assess thyroid function in children with SCD in correlation and iron load.

Patients and Method: This study was conducted on 40 children with SCD with iron overload (serum
ferritin more than 1000 ng/ml) including 22 males and 18 females with their ages ranging from 11-14
years and mean age value of 11.63±1.36 years and 40 healthy children of matched age and sex as a
control group. For all patients; complete blood count, hemoglobin electrophoresis, serum ferritin, serum
iron, iron binding capacity and thyroid function including Free Thyroxine (FT4), Free Triiodothyronine
(FT3), Thyroid Stimulating Hormone (TSH), Thyroid Peroxidase Antibody (TPOAb) and Thyroglobulin
Antibody (TgAb) were done.

Results:

Significantly higher serum ferritin and iron and significantly lower Total Iron Binding Capacity
(TIBC) were found in patients compared with controls (mean serum ferritin was
1665.2±1387.65ng/ml in patients versus 192.55±107.2ng/ml in controls with p-value of 0. 007, mean
serum iron was 164±83.9 ug/dl in patients versus 89.5±4.5ug/dl in controls with p-value of 0.039, mean
TIBC was 238±44.5ug/dl in patients versus 308±11ug/dl in controls with p-value of 0.001). Significantly
higher serum TSH and significantly lower Free T3 and Free T4 were found in patients compared
with controls with no significant correlation between thyroid hormones and serum ferritin (mean serum
TSH was 4.61±1.2 µIU/mL in patients versus 2.11 ± 0.54 µIU /mL in controls with p-value of 0. 045,
mean serum FT3 was 2.61 ±1.3 pg/mL versus 3.93±0.47pg/mL in controls with p-value of 0.027, mean
serum FT4 was 0.91±0.174 ng/dL versus 1.44± 0.164 ng/dLin controls with p-value of 0.047, r = - 0. 008
and p-value was 0. 973 for correlation between free T4 and serum ferritin, r = -0. 028 and p-value was 0. 9
for correlation between TSH and serum ferritin and r= - 0.259 and p-value was 0.27 for correlation betweenT3
and serum ferritin). There were no significant differences between patients and controls regarding
thyroid peroxidase antibody and thyroglobulin antibody (mean serum thyroid peroxidase antibody was
22.45± 4.32 in patients versus 22.45 ± 3.21 in controls with p-value of 0.98 while mean serum thyroglobulin
antibody was 12.32 ± 2.65 in patients versus 12.99 ± 2.34 in controls with p-value of 0.76.

Conclusion:

Thyroid hormones deficiency may occur in some patients with SCD.

Recommendations: Regular assessment of thyroid function in children with SCD may be recommended
as they are more vulnerable to develop hypothyroidism and may require replacement therapy.
Maximizing Biomass and Lipid Production in Heterotrophic Culture of Chlorella vulgaris: Techno-Economic Assessment
Authors: Morowvat Mohammad H. , Ghasemi Younes
Published: September 2018

Background:

Nowadays, chlorophycean microalgae have attained a broad-spectrum attention
as a potential candidate for biomass and bioenergy production. Despite their appreciated
benefits, one of major problems is their low biomass and lipid productivity. Here we investigated
the heterotrophic culture in shake flasks and stirred tank bioreactor to improve the lipid and biomass
production in a naturally isolated strain of Chlorella vulgaris.

Methods:

A naturally isolated C. vulgaris strain was cultivated in BG-11 medium in shake flask
and bioreactor. Its biochemical composition and growth kinetic parameters were investigated.

Results:

The biomass productivity was improved (3.68 fold) under heterotrophic culture compared
to basal autotrophic culture condition in shake flask experiment. The total lipid content increased to
44% of total Dry Cell Weight (DCW) during heterotrophic growth after 21 days. Moreover, a great
Fatty Acid Methyl Esters (FAME) yield was observed under heterotrophic cultivation. Total biomass
and lipid content of microalgae in bioreactor experiment increased to 4.95 and 2.18 g L-1 respectively,
during 5 days of the experiment compared to its basic autotrophic culture.

Conclusion:

The techno-economic aspects of exploiting C. vulgaris as a biodiesel feedstock werealso
evaluated. The results imply that heterotrophic cultivation could compensate the low biomass
productivity in microalgae for green energy production. Ever growing rates of established patents
on application of various genetic and bioengineering-based methods have made it possible to
achieve higher lipid contents with reduced total costs for microalgal biodiesel production as well.
A PARAMETRIC APPROACH FOR THE STUDY OF HEAT FLOW BETWEEN STREET CANYON AND THE ATMOSPHERE
Authors: Eusuf Muhammad Abu , Mohd Noor Salleh Wira , Al Mamun Abdullah , M. Adnan , Rahman Ataur , Eusuf Sabeek , Ibrahim Mansor
Published: September 2018

This paper presents the investigation results of the convective heat flow behaviour among the top of an urban street canyon and overlying atmosphere using a numerical model together with available field measurement data in variable geographical and meteorological conditions. It finds that the heat flow structure characterizes the street canyon have a strong relationship with narrowness index, outside wind velocity and latitude of the study area. The increase of the narrowness index and consequently, reduction of the sky-view factor leads to the diminution of heat flow exchange. The temperature of canyon surfaces in smaller narrowness index (n) decreases quickly to the lower degree than the temperature of the surface with larger (n) one. The increase of wind velocity outside of canyon makes this convective heat exchange flow higher, and cooler the street canyon. A parametric approach was established to evaluate this convective heat exchange flow based on the narrowness index, the latitude of the city and outside wind velocity.
IDENTIFYING THE LEVEL OF COMMUNITY INVOLVEMENT IN THE COMMUNITY ACTIVITIES AT KG. KUALA TELANG, KUALA LIPIS, PAHANG
Authors: Yaman Maheran , Baharuddin Zainul Mukrim , Mohd Jani Haza Hanurhaza
Published: September 2018

A community is a particular group of people that are bound by a similar cultural practice and activities. The continuation of the practising the local culture developed an identity for the community. Through time, the identity is strengthened by the level of community involvement in response to their participation in preserving the culture. The lack of community involvement would result to decreasing number of cultural practices. Eventually, the process contributed to a negative impact on the local identity. This paper addresses the importance of a community involvement concerning safeguarding the local culture and practices. Two objectives are outlined in achieving the aim. Firstly, to identify the list of the community activities. Secondly, to determine the level of community involvement at Kg. Kuala Telang, Kuala Lipis. A quantitative method of analysis is adopted in the paper to achieve the objectives. The survey questionnaire is distributed to 58 respondents, and the result is analysed using descriptive statistics and Spearman correlation tests. The findings from the data collection are arranged into four categories, and the result is discussed accordingly as to answer the aim and objectives of the paper. As a final remark, the paper highlights the importance of community involvement and the methods to ensure the level of participation in response to community activities in the village.
ASSESSMENT ON SITTING POSTURE RELATION TO RISK FACTORS BY USING CHI-SQUARE TEST AMONG ELDERLY TAXI DRIVERS IN PENINSULAR MALAYSIA
Authors: Abdul Majid Ahmad Zuhairi , Md Yusoff Irwan Syah , Mohd Tamrin Shamsul Bahri
Published: September 2018

There are numerous factors to take into account to ensure the elderly taxi drivers perform well at work while maintaining a good health. This paper is aimed to assess sitting posture of elderly taxi drivers in Peninsular Malaysia using chisquare test. A cross-sectional study was conducted with elderly taxi drivers using a self-administered questionnaire. The survey results deliver details of sociodemographic, work characteristics and sitting comfort of older taxi drivers. Purposive sampling was used targeting at 60 years old and older, self-driving taxi for at least 1 year, no disabilities and registered with Land Public Transport Commission (LPTC). A total of 120 respondents participated in the study. Most of the respondents used ‘hired’ car (76.7%). More than half of respondents had back pain in the past 12 months and 67.5% felt back pain in the last seven days. There are significant relationships (p< 0.05) between discomfort due to seat design and (i) BMI, (ii) smoking status, (iii) driving until midnight, (iv) feeling back pain for the last 12 months and last seven days. The lower body parts are susceptible to musculoskeletal disorders (MSDs) symptom and low back pain (LBP) injuries. Inappropriate sitting posture may cause discomfort and lead to MSDs. The lack of awareness on ergonomics design for sitting comfort lead to poor lifestyle and health issues among elderly taxi drivers in Malaysia.
Diagnostic model for Crohn�s disease based on magnetic resonance enterography layered bowel wall enhancement and apparent diffusion coefficient (Preprint)
Authors: Tomicka-Szymanska Barbara , Kaszubowski Mariusz , Winklewski Pawel J. , Pienkowska Joanna , Szarmach Arkadiusz , Szurowska Edyta
Published: September 2018

BACKGROUND

Human imaging research transitions from mapping local effects to developing predictive models that integrate information distributed across various MRI modalities.

OBJECTIVE

We hypothesised that based on magnetic resonance enterography (MRE) layered bowel wall enhancement and apparent diffusion coefficient (ADC), measured in the affected parts of the intestine, one would be able to effectively differentiate active and chronic phases of Crohn’s disease. The aim of this study was to create a multidimensional diagnostic model for differentiating between Crohn’s disease phases.

METHODS

This study included 125 patients, 55 women (44.0%; aged 19 to 66 years) and 70 men (56.0%; aged 12 to 67 years), who underwent MRE and ADC measurement for the first time. No patients had been previously treated for Crohn’s disease. The group of potential explanatory variables comprised 11 variables, including the thickness of the occupied section, length of the occupied section, number of lymph nodes present, layered bowel wall enhancement, total transitions on fat tissue, features of restricted diffusion in diffusion-weighted imaging (DWI), and ADC values.

RESULTS

The final discrimination model was based on only two variables, namely ADC (A) and layered bowel wall enhancement (W). Active Crohn’s disease was defined as -6.339 + 4.747 × W + 0.008 × A, while chronic Crohn’s disease was defined as -11.365 + 2.812 × W + 0.012 × A.

CONCLUSIONS

The predictive model described here could identify the active form of Crohn’s disease with a probability of 93.06% and the chronic form with a probability of 75.57%. The use of classic MRE layered bowel wall enhancement and a DWI-based ADC metric eliminates the main shortcomings of both approaches.

CLINICALTRIAL

Not applicable