bluuebunny/crossref_metadata_2025 huggingface dataset:
Responsabilidad profesional del médico
Authors: Moctezuma Barragán Gonzalo
Published: April 2022

Es indiscutible que toda profesión debe fundamentarse en una ética y la medicina desde sus orígenes ha sido consistente con ello. La ética médica es la base para generar confianza en el ejercicio de la medicina. Sin ella no es posible establecer, como todos lo sabemos, una satisfactoria relación médico-paciente. La sociedad debe saber que los médicos responden a una ética y que, por tanto, aplicarán todo su conocimiento y experiencia para mantener y, en su caso, recuperar la salud de los miembros integrantes del cuerpo social.
Mundos constitucionalmente posibles
Authors: Moreso José Juan
Published: April 2022

Algunas veces los conjuntos de normas jurídicas son concebidos como conjuntos estructurados por la relación de deducibilidad. De esta forma se han contemplado los sistemas jurídicos como sistemas estáticos, esto es, como sistemas que contienen todas sus consecuencias lógicas. Sin embargo, es un hecho notorio que el derecho cambia a través del tiempo, que existen actos de creación (promulgación) y actos de eliminación (derogación) normativa. Se sostiene, en virtud de ello, que los sistemas jurídicos son sistemas dinámicos.
Límites del modelo de ciencia jurídica actual. Exploraciones sobre el objeto de estudio del derecho
Authors: Sánchez Luis Manuel
Published: April 2022

Para efectos del análisis ensayado en el presente escrito denominaremos modelo epistemológico positivista jurídico al conjunto de proposiciones básicas, dominantes en el discurso jurídico contemporáneo y subyacentes al modelo de “ciencia jurídica” más difundido, las cuales definen el objeto de estudio del derecho, la metodología de su estudio, y la estrategia de su función dentro de la sociedad, condicionando en consecuencia, la actitud tecno-ideológica de los operadores encargados de suministrar y administrar el orden jurídico. Esta perspectiva puede denominarse genéricamente como positivista jurídica, o normativista, en razón al hecho decisivo de que se concentra en la explicación de la norma, o del sistema de normas, considerados positivamente dentro de un orden jurídico dado.
Sobre recepción de normas
Authors: Vilajosana Josep M
Published: April 2022

En un reciente trabajo, Moreso y Navarro (en adelante, M-N) se han ocupado del tema de la recepción de normas 1 . El estudio claro y profundo de M-N puede servir de guía para el planteamiento de diversos interrogantes sobre esta cuestión.
Sobre constitucionalismo y positivismo de Luis Prieto Sanchís
Authors: Carbonell Miguel
Published: April 2022

Luis Prieto Sanchís es uno de los más destacados filósofos del derecho de la España postconstitucional. Cercano a la escuela de filosofía del derecho de Gregorio Peces-Barba, actualmente es profesor en la Universidad de Castilla-La Mancha. Desde hace años se ha ocupado de problemas de interpretación jurídica 1 , conectándolos con las propias dificultades interpretativas que surgen en la aplicación de una Constitución normativa 2 . En el contexto jurídico español que surge después de la entrada en vigor de la Constitución de 1978 y sobre todo en el desarrollo de las tareas del Tribunal Constitucional español, las aportaciones de Luis Prieto han sido muy importantes.
Sobre relativismo cultural y universalismo ético en torno a ideas de Ernesto Garzón Valdés
Authors: Villoro Luis
Published: April 2022

La dominación de una cultura sobre otras consideradas inferiores ha aducido regularmente una justificación: la existencia de valores universales que esa cultura tendría el deber de realizar. El dominador se cree siempre portador de un mensaje “universal”, su revelación a otros pueblos es, según él, un bien impagable que justifica con creces el dominio. La expansión de la “única religión verdadera”, o de la “civilización” se pueden presentar como la cara benéfica del colonialismo, sólo porque se consideran de validez universal.
Diez mandamientos para la vida universitaria
Authors: Garzón Valdés Ernesto
Published: April 2022

Hace exactamente 30 años, invitado por Fernando Salmerón a quien había conocido en Alemania, llegué por primera vez a México e inicié mi relación académica con la UNAM, concretamente con el Instituto de Investigaciones Filosóficas. Allí conocí a Luis Villoro y a Alejandro Rossi y muy poco después a Olbeth Hansberg y a Margarita Valdés. Con todos ellos he cultivado, a lo largo de décadas, una entrañable amistad de la que me enorgullezco, con ellos proyectamos seminarios y cursos en la Argentina y en México, ¿te acuerdas Alejandro, te acuerdas Luis, de aquello que llamábamos «el tren de la libertad», metáfora ferroviaria para designar nuestro interés en mantener el más estrecho contacto posible a nivel intelectual y humano? Y conocí, por cierto, a los demás investigadores de ese ejemplar Instituto y también creo haberme granjeado su amistad. Y un buen día me encontré con Rolando Tamayo, ferviente kelseniano en aquel entonces y a quien traté de morigerar en su entusiasmo recurriendo a la obra de Herbert Hart.
Más allá de la soberanía y la ciudadanía: Un constitucionalismo global
Authors: Ferrajoli Luigi
Published: April 2022

Los significados tradicionales de soberanía y ciudadanía han sido puestos en cuestión por la crisis total del estado nación al que ambos están ligados: el primero, en tanto designa la completa independencia del estado de vínculos jurídicos internos y externos; el segundo, en tanto representa el status subjetivo de pertenencia a una comunidad política dada. La tesis que desarrollaré aquí es que los cambios asociados con esta crisis no pueden interpretarse como el advenimiento de nuevos tipos de soberanía y ciudadanía.
Entrevista a Luigi Ferrajoli
Authors: Suriano Ramón , Pisarello Gerardo
Published: April 2022

Luigi Ferrajoli nació en Florencia en 1940. Ha ejercido como juez entre 1967 y 1975, vinculado el grupo conocido como Magistratura Democrática. Desde 1970 es profesor de Filosofía del Derecho y de Teoría General del Derecho en la Universidad de Camerino. Es autor de una Teoría assiomatizzata del diritto (Milán, 1970) y del libro Democrazia autoritaria . capitalismo maturo, en colaboración con Danilo Zolo (Milán, 1978). En 1989 publicó Diritto. Ragione. Teoría del garan-tismo penale (editada en español por Trotta, Madrid, 1995), considerada uno de los mejores manuales contemporáneos de Derecho penal y Filosofía del Derecho. Entre sus últimas producciones se encuentra La sovranità nel mondo moderno (Roma, 1997).
THE IMPLEMENTATION OF PROJECT BASED LEARNING TO IMPROVE STUDENT LEARNING OUTCOMES IN STUDY ABOUT "PENGANTAR PANCASILA"
Authors: Nainggolan Deklay , Pontororing Hans Frans , Tinus Dominicus
Published: April 2022

This research was conducted to improve learning result of Students on semester 1 when study about “Pengantar Pancasila” by applying the Project Based Learning (PjBL) model. Data obtained in this study were obtained from observation, document study, test. Data analysis technique used is descriptive quantitative and qualitative with 41 people as sample from Guidance and Conseling Department, Faculty of Education, UNIMA. This study is a classroom action research (PTK) consisting of two cycles. Each cycle consists of two meetings, each of which consists of action planning, action implementation, observation and reflection and 1 evaluation meeting. The results showed that the application of learning model of Project Based Learning (PjBL) can improve student learning outcomes. At the pre cycle percentage of student learning 29% and then increased in the first cycle as much as 46% and increased again to 100% in cycle II.
Assessment of some immune markers in typhoid-patients
Authors: Medhat Ali Reyadh , Aljanabay Ahmed Abduljabbar Jaloob
Published: April 2022

A case-control study was carried out in the General Teaching Hospital in Balad City, Iraq. Eighty-eight male and female were included in this study; 58 typhoid-patients infected with S.typhi and 30 healthy individuals as controls. Acute typhoid-patients have been diagnosed according to positive blood culture and IgM and chronic typhoid-patients have been diagnosed according to positive stool culture and IgG. Four immunological markers have been measured in all individuals' serum; interleukin 4 (IL-4), interleukin 17 (IL-17), cluster of differentiation 8 (CD 8) and cluster of differentiation 22 (CD 22) using an Enzyme-Linked Immunosorbent Assay (ELISA). We diagnosed 32 and 26 patients infected with acute and chronic infection respectively, the results proved a significant increase (P-value=<0.05) in all markers in acute and chronic infections as compare with control. A significant differences P-value (0.0003 and <0.0001) has been proved between acute and chronic infection in IL-4 and IL-17 respectively. While, there was no significant differences P-value (0.13 and 0.32) between acute and chronic infection in CD8 and CD22 respectively. Conclusions: IL-4, IL-17, CD8 and CD22 serum levels increase in typhoid-patients caused by S.typhi in humans.
Role of platelet count in diagnosis of oral potentially malignant disorders and oral squamous cell carcinoma
Authors: Shukla Devashree , Shukla Chandresh , Singh Dilraj , Sharma Ayushi , Patel Nidhi , Mehta Dhaval Niranjan
Published: April 2022

Introduction: Platelets play an important role in the metabolic functions of malignant tissues. Platelet count is the major marker for malignancy and their increase in number can depict stages, severity and metastasis of cancer.  Increase in number of platelet count can be used in early diagnosis of cancer. However, use of some chemotherapeutic agents is associated with low platelet count. Therefore, the platelet to cancer cell ratio varies through the course of the disease and is highly affected by treatment. Aim: To assess correlation between platelet count and progression of malignancy. Materials and method: Platelet counts were retrieved from patients diagnosed oral potentially malignat disorders and oral squamous cell carcinoma based on clinical data. The collected data is analyzed to correlate the platelet count in oral potentially malignat disorders and oral squamous cell carcinoma compared to healthy control patients. Result: Nonsignificant differnce was noted in platelet count in oral potentially malignat disorders and oral squamous cell carcinoma compared to healthy control patients. Conclusion: Thrombocystosis is a poor predicator for malignancy, platelet count alone cannot determine the severity of malignancy, correlation with histopathologic data can better establish the grading of malignancy.
A study to evaluate the effectiveness of selected nursing interventions on control of anemia and worm infestation among male adolescents at Madurai
Authors: Thirunagalingapandiyan Paulchamy , Muthamilselvi G.
Published: April 2022

The main objective of the study was to evaluate the effectiveness of selected nursing interventions on control of anemia and worm infestations among male adolescents at Madurai. This study was employed at true experimental research design. Totally 60 male adolescents were included in the study. The study result showed that control group pretest mean hemoglobin value was 9.86 and standard deviation 0.54. Posttest meanhemoglobin 9.84 and standard deviation 0.60. Difference in mean percentage was 0.02.  Worm infection status was same (46.7 % no worm and 53.3% worm infestation) in pretest and posttest without any change. Among experimental group pretest mean hemoglobin value was 10.30 and standard deviation 0.78. Posttest mean 12.23 and standard deviation 1.05. Difference in mean percentage was 1.93. Worm infection status of pretest showed that 60% of the participants had worm load and 40 % no worm infection but in posttestall participants of experimental group were free from worm infection. The t value was 9.09  and p value of the study was less than 0.001.
Comparative characteristics of morphological changes in the pancreas under different types of irradiation in the experiment
Authors: Djahonkulovna Sultonova Lola , Abdullayevich Nuraliev Nekkadam
Published: April 2022

The aim of the study was to conduct a comparative characteristic of the morphological changes in the pancreas with different types of irradiation in the experiment. It has been established that a comparative description of the data of the first (acute irradiation) and the second group (chronic irradiation) of white outbred rats revealed 11 morphological signs indicating pathological changes in the pancreatic parenchyma, in terms of the intensity of occurrence of which differences were found that related to such morphological changes as atrophic changes in the interlobular excretory duct, stromal fatty degeneration, which were visualized only in animals of the first group. Plasma impregnation of vessel walls, atrophic changes in the parenchyma, atrophy of the islets of Langerhans were not found in all animals of the second group, while in the first group they were visualized in all rats. Comparative analysis shows that pathological changes in the pancreatic parenchyma of animals treated with acute irradiation were more intense, and more pathological signs were seen compared to chronic irradiation.
Combined drainage of the bilic and virsung ducts for the prevention of postoperative complications during pancreatoduodenal resection
Authors: Yakubov Yu. K. , Tillyashaikhov M. N. , Soipov B. D. , Sabirov S. S. , Tuyiev Kh. N.
Published: April 2022

Pancreatoduodenal resection is a standard procedure usually performed for benign and malignant tumors of the biliopancretoduodenal zone. The development and implementation of new technologies and techniques has made it possible to significantly reduce postoperative mortality to 5% over the past decade in specialized institutions around the world. But the number of postoperative complications still remains high - from 30% to 60% according to different authors; such as postoperative pancreatic and biliary fistulas, intra-abdominal infection, and late gastric emptying. Among them, pancreatic and biliary fistulas are the most frequent serious complications after pancreatoduodenal resection with a frequency of up to 30-60%, which is the main cause of postoperative mortality. In this work, we analyzed the internal intraoperative combined drainage of the pancreatic and bile ducts in 7 patients.
study of serum testosterone as a prognostic indicator in patients with respiratory failure on mechanical ventilation
Authors: Ashoka H G , Prakashini M V , Manthappa M , Ashok P
Published: April 2022

Patients on mechanical ventilation tend to have a multitude of biochemical changes, many due to adrenal suppression or functional adrenal insufficiency Abnormal levels of gonadal steroids poses significant physiologic effects in critically ill patients. Hypotestosteronemia, defined as a serum total testosterone level <250 ng/dL (<8.7 nmol/L) or free testosterone level <0.75 ng/dL (<0.03 nmol/L), is a common finding among male patients with critical illness. In this this study we determine if serum testosterone can be used as a prognostic indicator in patients with respiratory failure, on mechanical ventilation. This is a prospective observational study done over a period of 18 months at a tertiary care canter in Mysore. Study participants included male patients admitted to ICU of JSS Hospital with documented acute respiratory failure on arterial blood gas analysis (ABG), who were mechanically ventilated for more than 24 hours. Blood sample was collected at 24 hours and 72 hours post intubation and serum testosterone levels were estimated using Electro Chemiluminescence assay. Our results indicate 90.5% of the patients had low testosterone levels at 24 hours, whereas 97.1% of the patients had hypotestosteronemia at 72 hours post intubation.
Prognostic biomarkers in cardiovascular diseases
Authors: Karisnan Kanakeswary , Maziz Mohammad Nazmul Hasan , Sasongko Teguh Haryo , Karikalan Barani , Ibrahim Ruziah , Rafae Isriyanti Mohd , Mathialagan Amuthaganesh
Published: April 2022

The use of biomarkers as a reliable and reproducible indicative of the risk, severity, and progression of cardiovascular diseases (CVDs) may greatly enhance the prognostic capability of primary healthcare clinicians. In primary healthcare, the realistic and wise use of reliable biomarkers could minimize the time and costs for effective diagnosis and suitable personalized therapy for CVD patients. Therefore, the aim of the present scoping review is to evaluate the prognostic significance of biomarkers in the progression and monitoring of CVDs. The review was conducted according to the PRISMA-ScR guidelines. Eight databases were searched for articles published as of June 2021 using search terms: cardiovascular diseases AND biomarkers AND prognosis. A total of 21 studies were included in this scoping review. This review identified biomarkers BNP, cTnT yielded better accuracy of disease progression prediction in ACS and HF respectively. The availability of CVDs prognostic biomarkers in primary healthcare clinics could promote improved clinical outcomes of patients.
Antiemetic effect of intravenous palonosetron and ondansetron for the prevention of postoperative nausea and vomiting following laparoscopic surgeries under general anaesthesia, a randomised observational study
Authors: Chauhan Dinesh , Sharma Tejash , Naik Ganesh C.
Published: April 2022

Post-operative nausea and vomiting(PONV) is one of the common complications in patients undergoing laparoscopic surgeries under general anaesthesia. This study compares efficacy of prophylactic palonosetron and ondansetron in the prevention of PONV. After obtaining the approval of institutional ethical committee, a prospective randomised study was conducted on 60 patients belonging to American Society of Anaesthesiologists Grade I and II, patients of either sex, aged between 18 to 60 years, fulfilling the inclusion criteria were divided into two groups receiving inj. ondansetron 8 milligrams i.v. or inj. palonosetron 75 micrograms i.v. Incidence of PONV and need of rescue antiemetic was recorded post operatively. Data were evaluated statistically using Graph Pad Prism computer software version 6.04.It was found that inj. palonosetron 75mcg i.v. was more efficient in the prevention of PONV and required lesser rescue antiemetic when compared inj. ondansetron 8mg i.v. At conclusion of the study it was found that the prophylactic usage of inj. palonosetron 75 mcg i.v. is more effective than inj. ondansetron 8mg i.v. in the prevention of PONV in patients undergoing laparoscopic surgery (p value < 0.05).
Exosomal gene fold expression estimation of Leishmania major by real time qPCR in vivo and in vitro
Authors: Mjefi Manahel Hadi , Karam Muthanna Naeemah , Abdul-Gabbar Zainab , Al-Suraifi Ali Shakir K.
Published: April 2022

The aim of this research is to estimate the virulence factor L. major exosome by real time gene expression. The higher gene expression in footpad tissue was (29.34), the higher gene expression in day seven culture was (20.37), higher gene expression in day twelve culture was (12.25), highest gene expression in culture line control (8.33). The current work revealed that exosome gene expression was elevated in footpad in comparison to cultures media. The elevated levels were in passage three and lowest levels in passage one, in control culture line the level of gene expression was declined with progress of time.
Comparison of haemodynamic response to induction with propofol versus etomidate in patients scheduled for elective surgery
Authors: Mehta Jigisha B , Sharma Tejash H , Gopavajhula Venkata Suryanarayana , Desai Jayshri B , Chauhan Dinesh
Published: April 2022

Introduction: Laryngoscopy and endotracheal intubation are harmful stimuli that can produce adverse response in the cardiovascular, respiratory and other physiological systems. These changes are reflected in haemodynamic parameters which can be fatal for patients with low cardiac reserve and may alter the balance between myocardial oxygen supply and demand and as a result, myocardial ischemia can be precipitated. This observational comparative study was conducted to compare the haemodynamic effects of Propofol and Etomidate during induction of general anaesthesia in patients scheduled for elective surgery. Materials and Methods: 58 patients of American Society of Anaesthesiologists (ASA) physical status  I and II of age group 18-60 years scheduled for elective surgeries under general anaesthesia were randomly assigned in two groups (n=28). Group P received injection Propofol (2.5mg/kg) and group E received injection Etomidate (0.3mg/kg) during induction. Hemodynamic parameters were recorded at various time intervals. Statistical analysis was done using software (MedCalc Version 20.014). P value was considered significant if p £ 0.05. Results: Demographic profile was comparable in both the groups. Hemodynamic parameters at baseline and after premedication were comparable.
comparative study between McCoy laryngoscope versus the tascope in orotracheal intubation in adult surgical patients undergoing general anaesthesia
Authors: Patel Jatin , Shah Rajsi , Jain Akshay , Shah Arpit , Chauhan Dinesh
Published: April 2022

Introduction: McCoy laryngoscope and video laryngoscopes are being increasingly used as they offer advantages over the conventional laryngoscopes in airway management. The aim of this study is to compare and evaluate the efficacy of McCoy laryngoscope and TAScope in providing good glottic view and ease of intubation and observing the hemodynamic stress response. Materials and Methods: It is a randomised study including 60 patients aged 18-60 years with ASA grade I and II, divided equally in Group M and Group T, posted for elective surgery. Ease of intubation was evaluated by intubation difficulty score(IDS). Hemodynamic parameters, intubation time and airway trauma were compared in both the groups. Results: IDS TOTAL was higher in group M and was statistically significant (p<0.001). The mean time taken for intubation in group T was 46.08seconds and 26.53seconds in group M (p<0.001). There was a transient increase in pulse and blood pressure after laryngoscopy in both the groups but rise were less in group T. Less airway trauma was observed in group M as compared to group T. TAScope took more time compared to McCoy but it resulted in better first attempt intubation, provided more haemodynamic stability and less airway trauma as compared to McCoy.
Labor market, wage rates and unemployment
Authors: Astratova Galina V. , Bedrina Elena B. , Chowdhury Dababrata , Gaikar Vilas B
Published: April 2022

The rapid and undulating spread of the new dangerous COVID-19 infection across the world has exacerbated many socio-economic problems, showing the precariousness and vulnerability of modern civilization. The labor market was particularly hard hit under the current conditions, as it had been undergoing a gradual structural transformation in the previous period due to the digitalization of the economy, and was now forced to adapt at an accelerated pace to changes in the external environment under the influence of the pandemic and the response of the government to it. At the same time, the directions of adaptation were quite controversial, which led to the appeal to the chosen research topic. The authors conducted a comparative analysis and evaluation of adaptation practices. The following conclusions were made: 1) The pandemic confirmed the importance of non-price factors for the labor market; 2) Comparative analysis showed that the labor markets of developed and developing countries were affected unevenly; against this background, the Russian labor market, based on official statistics, looked quite positive; 3) The coronacrisis led to a widespread change in the structure of employment and demand for various groups of professions; 4) The pandemic forced enterprises to save on the wage fund
Eccentric domination path decomposition of Dumbbell graph
Authors: Gipson K. Lal , Jinisha Kalaiarasan K S
Published: April 2022

A decomposition (G_1,G_2,….G_n) of G is said to be Eccentric Domination Path Decomposition(EDPD) if i) G admits EDD ii) Each G_i is a path (1≤i≤n) iii) q(G_1 )=1 and q(G_2 )=2 or 3 iv) q(G_i )=3i-5 or 3i-4 or 3i-3, i=3,4….n.
Sellaturcica anomalies on lateral cephalometric radiographs and its relationship with class II skeletal malocclusion
Authors: Azam Aftab , Chauhan Ashish , Vashishta Vaibhav , Sahu Rakesh , Pramod Vattipalli , Sindhu Sai Sree D.
Published: April 2022

To know the relationship of morphological variation of sella turcica (ST) with Class II malocclusion. The sample in this study were 100 lateral cephalometric radiographs divided into two groups Class I and Class II skeletal malocclusion based on the ANB value, each group was randomized and identified by morphology of ST and later compared with the value ANB from each group. The findings of this study indicate a significant difference between morphological variation of ST in Class I and class II malocclusion. The normal morphology of ST was observed in, 68% of Class I and 12% of Class II skeletal malocclusion subjects. Irregular (notching) of the posterior wall was higher in Class II malocclusion (26%) and in Class I malocclusion, it was only 8%. To distinguish between normal and atypical appearances, the orthodontist should be conversant with the various morphologies of the ST.
Comparison of efficacy of three different venous occlusion duration on pre-treatment with injection ketamine to prevent propofol injection pain in patients undergoing surgery under general anaesthesia
Authors: Mehta J. , Desai J. B. , Jain Apurva
Published: April 2022

Propofol  is  rapidly acting intravenous agent used for induction in general anaesthesia.It causes  pain while administering,being uncomfortable to patients .So an observational study was done to compare the effects of different time duration of venous occlusion on pretreatment with injection Ketamine for prevention of pain at injection site. After approval of ethical committee and written informed consent,ASA grade I and II,60 patients of either gender, aged between 18-60 years were assigned to three groups of 20 each under GA and divided as GROUP K20,K40,and K60 according to venous occlusion duration of 20,40,and 60 seconds respectively on administration of ketamine(0.2mg/kg)as pretreatment for propofol injection pain.Following injection of ketamine ,25% dose of propofol was given and patient was asked for any sensation of pain at the site of injection and graded accordingly. Haemodynamics were compared in all the three groups. All 60 patients were reviewed for propofol pain and haemodynamics were recorded before pretreatment with ketamine and after pretreatment for 5 minutes and results evaluated through chi square test.P value was significant for 20 seconds (p value <0.001)but not for 40 and 60 seconds(p value  0.201)resulting in no difference in pain score between the two groups as compared to K20 group.
Immediate restorative rehabilitation of fractured tooth by fragment reattachment
Authors: Indi Shreeshail , Prakash Ghatole Kiran , Diwanji Pavan , Hambire Ashwini , Sulgante Sumapriya , Thimwalla Aadil
Published: April 2022

Dental trauma commonly leads to fracture of anterior teeth which affects the aesthetics and even has a psychological impact on the patient. Management of crown fractures depends on multiple factors like extent, pattern and the restorability of fracture to maintain the occlusion, aesthetics, and prognosis. If the fractured fragment is available, re-attachment is the most feasible option which is simple and economic providing good and long-lasting aesthetics, maintaining the original morphology and colour. This case report shows management of complex coronal tooth fracture by tooth fragment reattachment using metal post.
Implementasi Sistem Penjaminan Mutu Internal Perguruan Tinggi (Studi Tentang Standar Operasional Prosedur) di AMIK Citra Buana Indonesia 2021
Authors: Sulastri Winda
Published: April 2022

Penerapan SOP belum melalui tahapan prosedur kerja sesuai dengan standar yang telah ditetapkan dalam dokumen SOP dan proses implementasi SPMI yang dijalankan di AMIK CBI dan belum dilaksanakan secara maksimal sesuai dengan pedoman SPMI. Agar SOP dapat berjalan sebagaimana yang diharapkan, penulis merekomendasikan kepada seluruh komponen dalam manajemen AMIK CBI agar dapat segera mendorong terbangunnya komitmen bersama untuk mewujudkan tujuan SPMI di lembaga dan meningkatkan intensitas komunikasi dalam   proses implementasi SPMI. Para pengambil keputusan di lembaga harus mendorong ketersedian anggaran yang dapat mengoptimalkan proses penerapan SOP, serta mengoptimalkan kegiatan audit internal sebagai sarana evaluasi penerapan SOP untuk meningkatkan proses implementasi SPMI dalam mencapai tujuan AMIK CBI.
Pengaruh Kebijakan Standar Pendidikan Nasional tentang SDM dan Kompetensi Guru terhadap Mutu Pendidikan di SMA Plus Yaspida Kabupaten Sukabumi
Authors: Satya Budi Juli
Published: April 2022

Aplikasi ini dibuat berbasis web menggunakan php dan mysql. Perpustakaan AMIK Citra Buana Indonesia merupakan salah satu unit yang mendukung kemajuan pendidikan di lingkungan kampus sebagai sarana ilmu pengetahuan, pengumpulan dan penyebaran informasi. Untuk mencapai hal tersebut diperlukan suatu Sistem Informasi yang mampu menampilkan file dalam format file digital, sementara dikampus sendiri belum diterapkan system informasi perpustakaan secara digital; sehingga mahasiswa merasa kesulitan karena harus bolak balik menuju kampus untuk mencari referensi buku. Salah satu solusi untuk hal tersebut yaitu dengan menerapkan sistem informasi perpustakaan berbasis komputer atau sistem informasi perpustakaan  digital . Perpustakaan digital adalah perpustakaan yang mempunyai koleksi buku sebagian besar dalam bentuk format digital dan yang bisa di akses melalui komputer dan internet. Pembuatan sistem informasi ini menggunakan sistem pengembangan waterfall dan alat untuk membuat aplikasi ini dengan menggunakan bahasa pemrograman PHP dan MySql sebagai basis data. Hasil yang diperoleh pada aplikasi ini adalah mendapatkan Sistem Informasi Perputsakaan berbasis Komputer (digital library)  yang sudah terkategorikan berdasarkan jurusan. Perpustakaan digital ini di pakai dan di aplikasikan oleh AMIK Citra Buana Indonesia
Mainstreaming Restorative Justice in Termination of Prosecution in Indonesia
Authors: Silaswaty Faried Femmy , Mahmud Hadi , Suparwi Suparwi
Published: April 2022

By law, under the principle of opportunity, public prosecutors have been entitled to the authority to proceed or terminate the criminal cases under their authority. However, the termination of prosecution by the attorney generals is mostly not followed by a victim-oriented settlement. In this case, the principle of opportunity is not in line with the victim interest. On the other hand, the direction of legal reform in Indonesia promotes restorative justice approach in every criminal case settlement. In this regard, this article aims to investigate the way to implement restorative justice in case terminations by General Attorney of Indonesia. This research relies on socio-legal approach. Data were collected through the investigation of regulations and works of literature related to the termination of prosecution of criminal cases and restorative justice. The result of this study indicates that the regulation concerning termination of prosecution based on restorative justice is obviously departed from the public needs. According to General Attorney Regulation, restorative justice which is oriented to the public interest has the chance to be implemented as the basis for termination of prosecution of criminal cases; therefore, the penal court can be addressed as the last option (ultimum remidium).
Albino Mutants and Polyembryony in Saraca Asoca (Roxb.) de wilde
Authors: Mokat Digambar , Desai J. , Bhave S.
Published: April 2022

There is urgent need of Quality planting material (QPM’s) for the plantation of Saraca asoca tree. The study was undertaken for the nursery management. The albinism and polyembryony was noticed first time in the highly demanded medicinal plant Saraca asoca. The study was conducted during, 2008-2009 at Research Farm, College of Forestry, Dapoli (M.S.).
In vitro propagation of Asplenium aethiopicum through tissue culture
Authors: Sundari M. , Benniamin Asir , Jesubalan Doss , Sarkar Kaushik
Published: April 2022

Poor viability of spores and germination and slow growth in conventional vegetative propagation are major constraints in the in vitro culture of Asplenium aethiopicum, an important medicinal fern. In the present study, a procedure for in vitro propagation of this endangered fern through croziers has been established. Maximum sporophytes efficiency was obtained on KC media supplemented with growth regulators such as 0.5mg/l NAA & 0.5mg/l 2,4-D with 2 sucrose under photoperiod condition. Maximum frequency (33.2%) of callus formation and germination of sporophyte was observed on KC medium with growth regulators.
Immunostimulatory effect of ikan peda (fermented Rastrelliger sp.) water extract on IgM production by HB4C5 cells
Authors: Anindita Michaela Maria Kanya , Putra Agus Budiawan Naro , Sugahara Takuya
Published: April 2022

Ikan peda is one of Indonesia’s traditional fermented food products. It uses mackerel fish (Rastrelliger sp.), also known as ikan kembung in Indonesia, as its main ingredient. It is made through fermentation by adding high concentration of salt in order to extend the shelf-life and bring out the desired flavor of the fish. Although fermented foods are known to be beneficial towards health, fewer studies have been reported regarding the actual health promoting potential of Indonesian fermented foods, especially ikan peda. Thus, the immunostimulatory effects of ikan peda extract were examined. Water-extract of ikan peda was tested to human-human hybridoma HB4C5 cells. It was found that ikan peda extract stimulates the production of IgM by HB4C5 cells according to ELISA results. Data from real-time RT-PCR result showed that ikan peda extract has the ability to increase IgM gene expression by 3-fold at the highest concentration treatment. Results from the heat and enzyme treatments showed that the active substance contained in the ikan peda extract was expected to be a heat-stable protein. Although, the active substance and the mechanism is yet to be determined, and can be considered for future experiments. Our findings suggest that consumption of ikan peda would contribute to the promotion of health.
Inulin from Several Tubers Available in Indonesia and the Growth of Gut Microbiota
Authors: Crespo Ivan , Arindra Augusto , Lualdi Jessica Tashia , Rimba Phoebe Anadita , Putra Agus Budiawan Naro , Rahardja Ritchie
Published: April 2022

Indonesia has many types of tubers, some of them are gembolo tuber (Dioscorea bulbifera), lesser yam (Dioscorea esculenta), yam bean (Pachyrhizus erosus), and dahlia tuber (Dahlia pinnata); which are the sources of prebiotics. The term of prebiotics has been used since 1995 to describe the non-digestible components in food that positively alter gut microbiota activity and exhibit beneficial properties to the human body. One of the prebiotics that can be found in tubers is inulin. This review was aimed to compare inulin content in the above-mentioned tubers and their roles towards the growth of gut microbiota. Library searches using Semantic Scholar database was done. Findings showed that gembolo tuber contains the highest inulin content, followed by lesser yam, dahlia tuber, and yam bean. Moreover, inulin increases the population of Lactobacillus, Bifidobacterium, and Bacteroides while inhibits the growth of Escherichia coli and reduce the growth of Clostridium.
Meta-Analysis: Effectiveness of SSRIs vs SSRIs in conjunction with CBT in treating depression in young adolescents
Authors: Kresnia Gabriele Mustika , Hasuki Winda , Pradana ratnasari Nanda Rizqia
Published: April 2022

Objective: To compare the efficacy of SSRI medication alone and SSRI+CBT combined.

Methods: NCBI Pubmed, DARE, CSDR and NGC were searched October-November 2019. The population size, as well as the base and endpoint CGAS mean and standard deviation from the three studies included, are recorded. Statistical analysis was done in RStudio with the "meta" package.

Results: For the SSRI only, the effect size was -1.82 with a 95% confidence interval between -2.28 and -1.37.  For the SSRI and CBT combined, the effect size was -1.68 with a 95% confidence interval between -2.39 and -0.98. The effect size for both SSRI and SSRI + CBT didn't cross the null effect line, but the heterogeneity exceeds 50%. The result for the comparison of post SSRI vs. SSRI + CBT showed the effect size of -0.05 with a 95% confidence interval between -0.23 and 0.12. The size effect did cross the null effect line, but the heterogeneity was less than 50%.

Conclusion: Both methods were shown to be effective. However, due to statistical inconsistencies, it couldn’t be concluded whether the combination of SSRI and CBT is better than treatment with SSRI alone.
A Review of Phytochemical Properties and Therapeutic Activities of Glebionis coronaria
Authors: Wijaya Evelyn Jeanette , Nathanael Joshua , Carolan Orlando , Adiyanto Shakila Angjaya , Bun Wiranata Buntaran , Sahamastuti Agnes Anania Triavika
Published: April 2022

Glebionis coronaria, formerly Chrysanthemum coronarium, is one of the medicinal herbs that belong to the Asteraceae family. This review paper aims to provide information regarding the botanical description, distribution, and phytochemical properties which contribute to the medicinal properties of Glebionis coronaria. Various studies have reported the presence of tannins, vitamins, macro- and microelements, beta-carotene, carbohydrates, protein, and other bioactive compounds in the plant’s essential oil, extract, or plant parts. Researchers have uncovered the potential pharmaceutical activities of the plant, including antibacterial, antifungal, antioxidant, anti-inflammatory, anti-cholesterol, to the potential anticancer properties. Based on the scientific evidence collected, G. coronaria has the potential to be used in many clinical areas for medicinal purposes. However, appropriate clinical testing should be pursued to evaluate the medicinal effects of this plant.
Phytochemical Screening, Therapeutic Benefits, and Adverse Effects of Citrus aurantifolia - A Review
Authors: Chriscensia Erika , Wibowo Elizabeth Chrestella , Enriko Gregorius , Wijaya Owen Chrisfian , Sahamastuti Agnes Anania Triavika
Published: April 2022

Key lime or Citrus aurantifolia has been well known for its functions, either as food or medicine. This fruit has a greenish-yellow color with a sour and bitter taste and distributed initially from East Asia. This review summarizes the phytochemical screening, therapeutic effects, and adverse effects of key lime. Most parts of the plant contain phytochemicals, such as phenols, flavonoids, steroids, terpenoids, and alkaloids, with other varying compounds like saponin, tannin, anthraquinone, glycosides, and carbohydrates that may be due to the country where the plant is grown, or the extraction methods. Some studies have been conducted to evaluate the therapeutic effects of key lime, including antibacterial, antioxidant, anticancer or antitumor, anti-cholesterol, anti-larvae, anti-mosquito, antidiabetic, anti-inflammatory, and anticholinesterase. Key lime also may cause some adverse effects, such as phytophotodermatitis. It may lead to toxicity manifested in conditions such as edema, inflammation, or necrosis in some organs in the body, an increase in lymphocytes & liver enzymes, and a decrease in hemoglobin.
A Review of Botany, Phytochemical, and Pharmacological Effects of Dysphania ambrosioides
Authors: Hewis Lavisiony Gracius , Daeli Giovanni Batista Christian , Tanoto Kenjiro , Carlos Carlos , Sahamastuti Agnes Anania Triavika
Published: April 2022

Traditional medicine is widely used worldwide due to its benefits and healthier components that these natural herbs provide. Natural products are substances produced or retrieved from living organisms found in nature and often can exert biological or pharmacological activity, thus making them a potential alternative for synthetic drugs. Natural products, especially plant-derived products, have been known to possess many beneficial effects and are widely used for the treatment of various diseases and conditions. Dysphania ambrosioides is classified as an annual or short-lived perennial herb commonly found in Central and South America with a strong aroma and a hairy characteristic. Major components in this herb are ascaridole, p-cymene, α-terpinene, terpinolene, carvacrol, and trans-isoascaridole. Active compounds isolated from this herb are found to exert various pharmacological effects including schistosomicidal, nematicidal, antimalarial, antileishmanial, cytotoxic, antibacterial, antiviral, antifungal, antioxidant, anticancer, and antibiotic modulatory activity. This review summarizes the phytochemical compounds found in the Dysphania ambrosioides, together with their pharmacological and toxicological effects.
Recent Advancements of Fungal Xylanase Upstream Production and Downstream Processing
Authors: J Jonathan , Tania Veren , Tanjaya Jessica C. , K Katherine
Published: April 2022

Xylanase is a hydrolytic enzyme produced by fungi and bacteria utilized in various industrial applications such as food, biobleaching, animal feed, and pharmaceuticals. Due to its wide variety of applications, xylanase's large-scale industrial production has gained researchers' interest. Many factors and methods affect fungal xylanase's production in both upstream and downstream processing stages. The upstream production methods used are submerged fermentation (SmF) and solid-state fermentation (SSF), where SmF involves the usage of liquid substrates, while the SSF applies solid substrates to inoculate the microbes. The downstream processing of fungal xylanase includes extraction, purification, and formulation. The extraction methods used to extract fungal xylanase are filtration and solvent extraction. Meanwhile, the purification methods include ultrafiltration, precipitation, chromatography, Aqueous Two-Phase System (ATPS), and Aqueous Two-Phase Affinity Partitioning (ATPAP). The formulation of xylanase product is obtained in either liquid from the extraction-purification results, which can be converted to powder form using technologies such as spray drying to increase storage life. Moreover, immobilization of xylanase with nanoparticles of SiO2 could produce reusable xylanase enzymes. Several future studies have also been suggested. This review aims to explain the upstream and downstream processes of fungal xylanase production as well as the factors that affect those processes.
Implementation of an adverse childhood experiences screening protocol for adults at an outpatient medical psychology practice
Authors: Allain Jennifer , Creel Eileen , Perry Christy
Published: April 2022

Objective: Despite an abundance of evidence supporting screening adults for adverse childhood experiences (ACEs), the gap between this knowledge and screening persists. Evidence suggests that screening is warranted, feasible, and desired by patients. This feasibility study aimed to educate and train staff and providers on ACE screening and implement an ACE screening policy and protocol at an outpatient medical psychology practice. The two expected outcomes of this project, provider knowledge after ACE training and provider compliance with the ACE screening protocol, were measured to determine if a clinical practice change occurred.Methods: A quasi-experimental design with a pre-test/post-test was used to determine increases in provider knowledge following an ACEs training intervention. Additionally, post-intervention only data collection was used to determine compliance with ACE screening protocol, to determine practice change and feasibility of continued protocol use.Results: The project results indicated that the implementation of the ACE screening protocol was feasible. Thirty-three adult clients new to the practice completed the ACE screening. Of the 33 clients screened during the 12-week study, 26 clients had an ACE score of three or higher, and 14 (42%) received therapy referrals based on their ACE score after education and discussion by the intake therapist. Weekly chart checks revealed that 100% of clients screened received, at a minimum, the educational packet regarding the impact of ACEs on physical and mental health. The protocol encouraged providers to promote evidence-based interventions to mitigate the potential untoward outcomes associated with ACEs.Conclusions: These findings reflected a change in knowledge based on education and indicated that educational intervention was effective.
Solar effect on rainfall in West Bengal
Authors: CHAKRABORTY PK , BONDYOPADHAYA R
Published: April 2022

The General characteristics of rainfall and it's correlation with sunspot during 1931-81 over 8 stations in West Bengal have been studied. An average dispersion of ~ 20% has been noticed with an increasing tendency for decreasing latitude. Three years moving average analysis reveals that whenever the sunspot number increases or decreases the rainfall does so almost simultaneously except during solar max. years. But average period of rainfall cycle is half of the period of solar cycle, i.e., 5.5 years, a period compatible with the southern oscillation. Moreover, in SS maximum years the rainfall decreases with the increase of SS number. Calculations of average rainfall during different sunspot phases indicate that the annual rate of rainfall is greater during solar maximum to minimum phase than that during minimum to maximum phase. However, the difference in the annual rates is not much, only 15% for two stations and much less for other stations. Using a growth rate model it is found that in 69% cases the rainfall decreases as sunspot number decreases. Further when the growth rate and other studies of rainfall in Sub Himalayan West Bengal and Gangetic West Bengal arc made separately it appears that the rainfall of these two regions are oppositely affected by solar activities. The correlation coefficients between rainfall and sunspot of same year, of previous year and of two years before have come out as <= + 0.35 and mostly it is positive. Further, sunspot's influence seems to be most effective on rainfall of the following year.
Dynamic Latent Dirichlet Allocation Tracks Evolution of Online Hate Topics
Authors: Rhys Leahy Richard F. Sear , J. Restrepo Nicholas , Lupu Yonatan , Johnson Neil F.
Published: April 2022

Not only can online hate content spread easily between social media platforms, but its focus can also evolve over time. Machine learning and other artificial intelligence (AI) tools could play a key role in helping human moderators understand how such hate topics are evolving online. Latent Dirichlet Allocation (LDA) has been shown to be able to identify hate topics from a corpus of text associated with online communities that promote hate. However, applying LDA to each day’s data is impractical since the inferred topic list from the optimization can change abruptly from day to day, even though the underlying text and hence topics do not typically change this quickly. Hence, LDA is not well suited to capture the way in which hate topics evolve and morph. Here we solve this problem by showing that a dynamic version of LDA can help capture this evolution of topics surrounding online hate. Specifically, we show how standard and dynamical LDA models can be used in conjunction to analyze the topics over time emerging from extremist communities across multiple moderated and unmoderated social media platforms. Our dataset comprises material that we have gathered from hate-related communities on Facebook, Telegram, and Gab during the time period January-April 2021. We demonstrate the ability of dynamic LDA to shed light on how hate groups use different platforms in order to propagate their cause and interests across the online multiverse of social media platforms.