bluuebunny/crossref_metadata_2025 huggingface dataset:
PROTON-PUMP INHIBITOR USE AND POTENTIAL DRUG INTERACTIONS IN OUTPATIENTS
Authors: Syafhan Nadia Farhanah , Augustine Maulidya , Ramadhani Uci , Hersunaryati Yetti
Published: December 2018

Objective: This study aimed to evaluate the use and potential drug interactions of proton-pump inhibitor (PPI) in outpatients.Methods: This study is a retrospective descriptive analysis of prescriptions and medical records from outpatients in Gatot Soebroto Army Hospitalselected by purposive sampling who received PPI with one or more other drugs from July to December 2015. The analysis was conducted on 400prescriptions from 192 patients.Results: Data showed that 100% of the PPI therapy utilized was appropriate for the patients’ condition, 79.00% was appropriate for the indication,79.00% was appropriate for the dosage, 79.00% had an appropriate administration duration, and 83.75% was given the appropriate drug. Thepotential of PPI interactions with other drugs was found in 324 prescriptions (81.00%) from 475 cases. Of all the cases, 42 were considered majorinteractions, 138 were moderate interactions, and 295 cases had minor interactions. There were 14 drugs that could potentially interact with PPI, suchas mycophenolate mofetil, clopidogrel, cilostazol, warfarin, iron, levothyroxine, propranolol, cyclosporine, simvastatin, atorvastatin, cyanocobalamin,sucralfate, theophylline, and antacids.Conclusion: PPI use in outpatients at the Gatot Soebroto Army Hospital was not entirely appropriate and had a large number of potential druginteractions with concurrent drugs.
SYNTHESIS AND ANALYSIS OF ZINC-METHIONINE, ZINC-TRYPTOPHAN, COPPER-LYSINE, AND COPPER-ISOLEUCINE COMPLEXES USING ATOMIC ABSORPTION SPECTROPHOTOMETRY
Authors: Koppa Nadhila Adani , . Harmita , Jatmika Catur
Published: December 2018

Objective: This study aimed to synthesize an organic form of Zn and Cu to then produce metal complexes with amino acids, as well as to analyze thefree and bound metal content of the complexes.Methods: In this study, the synthesis methods for zinc-methionine (Zn(Met)2), zinc-tryptophan (ZnTrp), copper-lysine (Cu(Lys)2), and copperisoleucine(Cu(Ile)2) complexes were based on previous studies. Sample verification was conducted using Fourier transform infrared spectroscopy,which can determine the stretched spectra produced by the complexes. In addition, atomic absorption spectrophotometry was used to analyze themetal content of the complexes.Results: The yields gained from the synthesis of Zn(Met)2, ZnTrp, Cu(Lys)2, and Cu(Ile)2 complexes were 95.99%, 94.18%, 91.89%, and 95.73%,respectively, with a maximum metal content of 199.51, 246.98, 176.99, and 189.75 mg/g, respectively.Conclusion: The mineral concentration of each complex differed, depending on the type of mineral and ligand.
Professor, minha Prova está em Branco(!): uma experiência de compartilhamento com alunos da responsabilidade de construir e corrigir uma avaliação no ensino superior
Authors: Cardenas Alfredo Ribeiro
Published: December 2018

Este trabalho objetiva apresentar um relato de experiencia da aplicação de uma dinâmica de avaliação alternativa de prova teorica/escrita. Trata-se, fundamentalmente, de uma atividade pedagogica em que os alunos, agrupados em duplas, constroem as perguntas de uma prova teorica, respondem as perguntas de outros alunos, avaliam as respostas às suas perguntas e, tambem, sao avaliados pelas perguntas construidas. A dinâmica avaliativa foi aplicada na disciplina de Gestao da Inovação, em um curso de graduação, em uma IES pública do sul do pais. Criatividade na forma de construção das perguntas e a utilidade do seu conteúdo sao os parâmetros estabelecidos para avaliar os participantes da atividade. Todos os passos da criação e aplicação da dinâmica avaliativa sao relatados no texto, alem de sugestoes de variação da atividade.
Análise da Dimensão Didático-pedagógica no Desempenho de Estudantes de Engenharia Química do Rio Grande do Sul
Authors: Dossin Zanrosso Crissie , Andreatta Carvalho da Costa Luciano , Kinast Eder Júlio
Published: December 2018

A presente pesquisa trata da qualificação didático-pedagógica de professores engenheiros a partir de um aporte teórico. Um levantamento da qualificação docente foi realizado para diagnóstico dos cursos de engenharia química das Instituições de Ensino Superior (IES) do Rio Grande do Sul, a partir de informações contidas no currículo Lattes. Variáveis como gênero, titulação e natureza da instituição foram cruzadas estatisticamente com a qualificação docente. Além disso, buscou-se correlacionar estes dados ao desempenho dos alunos através do Exame Nacional de Desempenho de Estudantes (ENADE) e do crescimento médio no número de formandos. Os resultados sugerem que a qualificação dos professores poderia ser aprimorada. Ainda, há mais professores qualificados nas IES privadas do que nas públicas. Por fim, verificou-se que as IES com os maiores números de docentes com qualificação didático-pedagógica apresentaram também o maior crescimento no número de formandos nos últimos cinco anos.
O narrador/profeta em A hora da estrela, de Clarice Lispector
Authors: Lopes Paulo César Carneiro
Published: December 2018

Há em A hora da estrela continuidades e rupturas com relação ao restante da obra de Clarice Lispector. No que se refere ao narrador, pela primeira vez temos uma experiência radical de alteridade no sentido que o filósofo Lévinas dá ao termo. No que se refere à continuidade, podemos pensar Rodrigo S.M. como um outro da própria Clarice; há entre eles diferenças, mas estas se mostram mais como elementos da subjetividade profunda da própria autora. Já no que se refere à Macabéa, não se dá o mesmo; entre ela e Clarice/Rodrigo há diferenças radicais que não se resolvem apenas neste sentido. Ela é o outro negado em sua dignidade que, pelo seu existir, exige o ato de justiça que desfaça as condições que geram sua situação calamitosa.Palavras-chave: Clarice Lispector; A hora da estrela; Freud, Emmanuel Lévinas e Enrique Dussel; Moisés e os profetas.
Da Alteridade e da Identidade: o Caso dos Estudos Anglo-Portugueses
Authors: Terenas Gabriela Gândara
Published: December 2018

O presente artigo pretende discutir a noção de alteridade em articulação com a de identidade, defendendo a indissociabilidade de ambas, nomeadamente no respeitante à construção de imagens do Eu e do Outro. Depois de uma perspectiva teórica assente em autores como Lacan, Hall, Bakhtine, Bhabha, Beller & Leerssen, entre muitos outros, o artigo centra-se no caso dos Estudos Anglo-Portugueses, cuja fundamentação teórica se baseia justamente nos dois conceitos referidos – alteridade e identidade –, ou seja, na relação entre o Outro (anglo ou luso) e o Eu (português ou anglo). Mediante a análise de diversos tipos de textos, a tarefa do investigador em Estudos Anglo-Portugueses reside em desconstruir os respectivos discursos e diagnosticar os processos através dos quais se estabelece uma relação inevitável entre alteridade e identidade.PALAVRAS-CHAVE: Alteridade; identidade; anglo-portugueses; eu/outro; imagologia.
No encontro com o “outro” acontece a revelação, epifania
Authors: Sa Olga de
Published: December 2018

O artigo trata da Epifania sob o ângulo específico da alteridade e suas implicações na educação para a formação humana. A pesquisa é de cunho qualitativo e bibliográfico e se fundamenta na obra de Clarice Lispector e de Levinas.
Yüksek Teknoloji İçeren Ürün İhracatının İhracat Hacmi Ve Ekonomik Büyüme Üzerine Etkisi; Seçilmiş OECD Ülkeleri ve Türkiye Örneği
Authors: KONAK Ali
Published: December 2018

Küreselleşme olgusunun son
derece hızlı ivme kazanmaya başladığı günümüz modern dünyasında ülkeler
arasındaki yapay sınırlar ve engeller bir bakıma ortadan kalkmış ülkeler
ekonomik ve siyasal yönden birbirlerine daha bağımlı bir hale gelmişlerdir.
Ülkelerin uluslararası piyasalardaki rekabet gücünü ve etkinliğini artırmasının
yolu, uluslararası piyasalarda kabul görecek yüksek teknoloji içeren ürünlerin
üretilmesinden ve ihraç edilmesinden geçmektedir. Bu sayede elde edilecek ihraç
gelirleri, ülkelerin ekonomik büyümesi, kalkınması ve ekonomik geleceği
açısından hayati bir önem arz etmektedir. 
Seçilmiş
OECD üyesi ülkelerin ve Türkiye’nin yüksek teknoloji içeren ürün ihracatının
büyüklüğünü, gelişimini ve ekonomik büyüme üzerindeki etkilerini incelemek
amacıyla 1992-2016 dönemine ait Dünya Bankası verilerinden yararlanarak
hazırlanmış olan bu çalışmada veri analiz yöntemi kullanılmıştır. Yapılan analiz neticesinde Türkiye’nin toplam ihracatı
içerisinde yüksek teknoloji içeren ürün ihracatının payının, incelen dönem
itibariyle 1999-2001 yılları hariç olmak üzere %2 seviyesinden daha aşağı
seviyelerde gerçekleştiği, 1999-2001 alt döneminde ise söz konusu oranın ancak
%4 seviyesine kadar yükselebildiği, Türkiye’nin ihracatının ağırlıklı olarak
“düşük”, “düşük-orta” ve “orta-ileri” teknolojilere dayalı olduğu tespit
edilmiştir. Türkiye bu konuda diğer OECD üyesi ülkelerin oldukça gerisinde yer
almaktadır.
Social Media Influence on the Millennial Generation's Civic Disposition
Authors: Novitasari Novitasari
Published: December 2018

The development of science and technology encourages most people to follow the changes that occur in the world including the use of the internet as a daily necessity. The internet has become inherent in human life, especially in the millennial generation today because it makes it easier to communicate and exchange information, including in Indonesia. However, the impact caused in the use of social media is not always realized by the user so that it can lead to something that is not desired. Therefore, this study aims to determine how the impact of the use of social media affects the civic disposition of users, especially the millennial generation. The research approach used is a qualitative research approach with descriptive research methods. The researcher collected data through observation, interviews, and documentation studies. The results of the study indicate that social media can support the strengthening of national integration because of some of its functions. The culture of mutual cooperation and the love of the country can grow and develop in the community, especially social media users. Then the researcher gave recommendations based on the findings of the research, namely the need for an anticipatory and selective attitude for all parties, especially social media users and other interested parties.

Keywords: social media, millenial generation, civic disposition

Abstrak

Perkembangan ilmu pengetahuan dan teknologi mendorong sebagian besar manusia mengikuti perubahan yang terjadi di dunia termasuk penggunaan internet sebagai kebutuhan pokok sehari-hari. Internet telah melekat dalam kehidupan manusia terutama pada generasi millennial dewasa ini karena memudahkan berkomunikasi dan bertukar informasi termasuk di Indonesia. Akan tetapi, dampak yang ditimbulkan dalam penggunaan media sosial tidak selalu disadari oleh pengguna sehingga dapat mengarah pada sesuatu yang tidak dikehendaki. Penelitian ini bertujuan untuk mengetahui bagaimana dampak penggunaan media sosial berpengaruh terhadap civic disposition pengguna terutama generasi milenial. Pendekatan penelitian yang digunakan adalah pendekatan penelitian kualtitatif dengan metode penelitian deskriptif. Peneliti mengumpulkan data melalui observasi, wawancara, dan studi dokumentasi. Hasil penelitian menunjukkan bahwa media sosial dapat mendukung penguatan integrasi nasional karena beberapa fungsi yang dimilikinya. Budaya gotong-royong dan rasa cinta tanah air dapat tumbuh dan berkembang pada masyarakat terutama pengguna media sosial. Kemudian peneliti memberikan rekomendasi berdasar pada hasil temuan penelitian, yaitu perlunya sikap antisipatif dan selektif bagi semua pihak terutama pengguna media sosial dan pihak lain yang berkepentingan.

Kata kunci: media sosial, generasi milenial, civic disposition
Bioluminescent imaging: new opportunities
Authors: Osipova ZM , Shcheglov AS , Yampolsky IV
Published: December 2018

Modern biomedical research technologies actively use bioimaging for studying cells, tissues and whole organisms. Multicolor bioimaging is applied when simultaneous observation of different events at the molecular and cellular level is needed. Bioluminescent imaging methods are the most sensitive, however, their use for multicolor labeling is complicated due to the insufficient number of available uciferin-luciferase pairs. Having a number of advantages compared to previously studied bioluminescent systems, the new bioluminescence systems of higher fungi and marine polychaete Odontosyllis could become a useful expansion of the bioimaging toolbox.
Testing of monoclonal antibodies against the T-cell receptor associated with ankylosing spondylitis
Authors: Israelson MA , Stepanov AV , Staroverov DB , Shagina IA , Misorin AK , Evstratieva AV , Merzlyak EM , Bogdanova EA , Britanova OV , Lukyanov SA
Published: December 2018

In the last decade there has been a tendency to move away from the symptomatic treatment and embrace targeted therapies. This process is underpinned by the accumulated knowledge of the mechanisms underlying the pathogenesis of diseases and driven by the advances in biotechnologies. T-cell receptors with variable TRBV9 β-chain regions have been recently associated with spondyloarthritis including its subtype, ankylosing spondylitis. The aim of this work was to engineer a chimeric monoclonal antibody targeting the variable region of the T-cell receptor β-chain encoded by the TRBV9 gene segment and assess its specificity and cytotoxicity. Using flow cytometry and next generation sequencing, we demonstrate that the engineered chimeric antibody is highly specific and exhibits cytotoxic activity against its target. Approaches based on the use of therapeutic chimeric antibodies against pathogenic T-clones may hold great promise for the therapy of autoimmune disorders in general and AS in particular.
THE CURRENT PROBLEMS OF URBAN DEVELOPMENT IN CLUJ METROPOLITAN AREA
Authors: BACIU Nicolae , ROŞIAN Gheorghe , MUNTEAN Octavian-Liviu , MĂCICĂŞAN Vlad , ARGHIUŞ Viorel , MIHĂIESCU Radu
Published: December 2018

The Cluj Metropolitan Area is located in Cluj County, the north-western development region of Romania. The strategic option of polycentric territorial development was adopted on the basis of the principles outlined in the NDP (National Development Plan)- on spatial development at regional level. This involves supporting development processes within urban growth pole. The associative structure at the Cluj Metropolitan Area (CMA) was formed at the end of 2008, continuing the efforts to establish a metropolitan area with economic specificity, initiated by Cluj County Council in 2006. Communes included in Cluj Metropolitan Area are also part of different micro-regional associations with relatively homogeneous characteristics. These associations were formed at the initiative of city halls and they have legal personality.
THERMAL WATER AND RADON EXPOSURE THROUGH THE SKIN
Authors: CIORBA Daniela , MOLDOVAN Mirela , COSMA †Constantin , HOFMANN Werner , MOLDOVAN Mircea
Published: December 2018

Low doses - non cancer effect involve also, exposure to RADON alpha particle, through the skin, during radioactive thermal baths. Alpha radiation is considered to have a high impact on the immune-suppressive cytokine and to a certain degree it can influence the temporary regeneration of impaired health function in autoimmune patients, due to their analgesic and anti-inflammatory properties. Considering the benefits of thermal water with 30 Bq/l Radon, from Felix-Oradea, Spa Resort, Bihor county, Romania, we analysed the variation of skin biophysical parameters like hydratation (HYDR), trans epidermal water loss (TEWL), sebum quantity (S), and skin surface temperature (T), for different water ‘temperatures, looking comparatively between the left hand submerged in radioactive water and the right hand, submerged in normal water.
COMPARATIVE STUDY REGARDING THE RISK PERCEPTION OF TSUNAMIS FROM EFORIE NORD (ROMANIA) AND NICE (FRANCE) COMMUNITIES
Authors: CONSTANTIN Angela Petruţa , MOLDOVAN Iren-Adelina , PARTHENIU Raluca , LAVIGNE Franck , GRANCHER Delphine , IONESCU Constantin
Published: December 2018

The goal of this paper is to present a comparative study of the people perception from two different sites from Romania and France, regarding the tsunami risk in the Black and Mediterranean Seas communities. These two surveys over residents’ and tourists’ perception and preparedness of tsunami hazard were carried out for both towns, Eforie Nord(Romania) and Nice (France), in the frame of the ASTARTE project – „Assessment, Strategy And Risk reduction for Tsunamis in Europe” (EC Programme FP7).Data were collected by tsunami questionnaire developed in the project and translated in Romanian and French languages, and the questions are referring to: interviewee's relation to Eforie Nord and Nice sites, information about interviewed people, tsunami hazard knowledge/risk perception, evacuation issue, awareness of the existing warning system, information, and communication. A total of 256 subjects participated at surveys from both sites situated along coasts of Black and Mediterranean seas. The results of the survey showed a moderate level of tsunami preparedness and perception of people living in, working in, or visiting Eforie Nord and Nice sites, our respondents mentioned the tsunami as third rank in both sites, coming after earthquakes and storms/pollution. Whatever the respondent's status (i.e. local population, or tourists), earthquakes and sea withdrawal are cited as tsunami warning signs by 62% and 60% of the respondents from Eforie Nord and by 30% and 31% of the respondents from Nice, respectively. When considering a future tsunami being generated in Eforie Nord, 36,3% of the respondents think that the place could be affected by a tsunami and the waves could reach more than 2-5 meters (heights cited by approx. 14% of respondents) or even more than 5-10 meters (values cited by 15% of interviewed people). Regarding the Nice site, 78% of the respondents think that the place could be affected by a tsunami in the future. With such a negative perception of tsunamis, it is not surprising that more than 29% of the respondents from Nice site expect waves of more than 10 m high. This study provided evidence that tsunamis recently occurred in the world have a significant impact on people’s preparedness and perception.
ECO-FRIENDLY RECYCLING POTENTIAL OF MICROWAVE MELTING FOR THE RECOVERY OF USEFUL AND PRECIOUS METALS FROM E-WASTE
Authors: DUMITRESCU Daniela Violeta , SOARE Vasile , CONSTANTIN Ionuţ , BURADA Marian , OLARU Mihai , CÂRLAN Beatrice , DRĂGOESCU Marius , VÂLCAN Angela
Published: December 2018

The processing of waste electrical and electronic equipment (WEEE) has become an issue of significant importance due to the large volumes being generated and to the content of rare and valuable metals as well as environmentally toxic materials (organic compounds). Presently, WEEE is regarded as an important secondary resource of useful metals.The aim of this study is to evaluate the content of base and precious non-ferrous metals in such wastes collected in Romania and to assess the potential of their recycling through processing in microwave field.Electric and electronic wastes are complex mixtures of materials and components, with chemical compositions which depend on their sources (printed circuit boards - PCBs, mobile phones, television and radio sets, home appliances and industrial equipment). In PCBs the metallic fraction is of approximately 30-50 wt.% (with 45-65 wt.% Cu, 0.5-20% Pb, 15-25% Sn, 5-8% Zn, 0.4-0.8% Ag, 0.08-0.2% Au and 2-5% other metals such as Fe, Ni, Al, Sb, Cr, Mn etc.). The non-metallic fractions, which account for 50-70 wt.%, contain substances such as brominated flame retardant, thermosetting resin, reinforced materials and other toxic and hazardous organic compounds. The combustion of these materials during the pyrometallurgical processes may cause serious environmental problems, due to the generation of toxic gases.The microwave melting of WEEE represents a promising state-of-the-art, ecological and energy efficient alternative for the conventional methods with a remarkable applicative potential. The advantages of this method are: i. reduced melting time with energy savings of 30-40%, compared to traditional processes (a microwave furnace can easily attain temperatures up to 1600°C in less than 30 minutes); ii. low content of organic substances. iii. facile extraction of the enclosed metal fractions; iv. improved process control; v. absence of direct contact with the melting materials and vi. environmental-friendly approach through the possibility of treating the toxic gas emissions in a microwave field at high temperatures (1300 ÷ 14000C).
COMPARISON BETWEEN TSUNAMI MODELING SCENARIOS FOR SHABLA AREA (BLACK SEA) USING TWO DIFFERENT SOFTWARE
Authors: PARTHENIU Raluca , CONSTANTIN Angela Petruţa , MOLDOVAN Iren-Adelina , IOANE Dumitru
Published: December 2018

There are evidences of 22 past tsunamis generated in the Black Sea area. Shabla area is the most dangerous for the Romanian shoreline and triggered past high magnitude earthquakes and tsunamis. According to National Oceanic and Atmospheric Administration (NOAA) data base, 3 important events occurred in Shabla: the most recent, on 31st of March 1901, an earthquake of magnitude 7.2 triggered waves of 5 m, other sources estimating 2.5 - 3 m; the oldest documented event, in the1stCentury BC, in Bisone area, and the third one, year 543 AC, when a 7.5 magnitude earthquake generated tsunami waves of 2 - 4 m.
Tsunami modeling was accomplished for Shabla area using two software, Tsunami Analysis Tool (TAT) and TRIDEC Cloud, and past earthquake parameters (location, depth, focal mechanism). A comparison between the results of the two software was accomplished, for the same input parameters:  magnitudes of 7, 7.2, 7.5 and 8, depths of 5, 10 and 30 km and 5 fault plane solutions. The worst case scenario with TRIDEC software displays waves of maximum 2.62 m in Varna, for a magnitude 8 and a depth of 5 km, with 0.32 m in Constanta; the worst case using TAT software shows maximum waves of 4.3 m in Kamen Bryag, with 4Romanian locations affected (2 m waves in Costinesti). Moderate waves are given by scenarios using magnitude 7.5, with 0.6 - 0.8 m heights. For lower magnitudes (7 - 7.2), the modeling estimates very low waves, 0.2 - 0.4 m.
“THERE WAS A BLACK GAP WHERE THE DE HAD BEEN:” DISPOSSESSING DISCOURSE IN AIDAN HIGGINS’ “BALCONY OF EUROPE”
Authors: POPA PETRAR Petronia
Published: December 2018

“There Was a Black Gap Where the DE Had Been”: Dispossessing Discourse in Aidan Higgins’ ”Balcony of Europe”. My paper attempts to explore a novel by Irish writer Aidan Higgins from the perspective of the so-called “ethical turn” in the study of narrative by arguing that both its form and its content explicitly thematise the ethical risks of the first-person discourse when it comes to representing the other. Using Dorothy J. Hale’s notion of the voluntary “self-binding” fiction requires from the “responsible readers,” I examine the strategies through which Higgins pits the narrator’s failure to represent otherness against the imminent disintegration of the European landscape, history and identity under the pressures of a discourse of possession and rigid localisation. To these pressures, the text responds by suggesting the language of fiction has the potential to criticise and counteract possession as a model for identity through the effort it imposes on the readers to simultaneously exert and limit their individual freedom.
Rezumat. „În locul lui DE era o gaură neagră:” deposedarea discursului în “Balconul Europei” de Aidan Higgins. Lucrarea de față își propune lectura unui roman aparținând scriitorului irlandez Aidan Higgins din perspectiva „întoarcerii la etică” în studiul narațiunilor, pornind de la premisa că forma și conținutul acestuia pun explicit în temă riscurile etice ale discursului la persoana I în ceea ce privește reprezentarea alterității. Utilizând definiția dată de Dorothy J. Hale noțiunii de „autolimitare” impusă de roman cititorilor „responsabili,” lucrarea investighează strategiile prin care Higgins suprapune eșecul naratorului de a reprezenta alteritatea dezintegrării iminente a peisajului, istoriei și identității europene sub presiunea unui discurs al posesiei și al localizării rigide. Textul răspunde acestei presiuni prin sugestia că limbajul ficțional are potențialul de a critica și a se opune posesiei ca model identitar prin efortul cerut cititorului de a-și exercita și limita simultan libertatea.
Cuvinte cheie: etica narativă, “deposedare” lingvistică, reprezentare ficțională, alteritate.
SAMUEL BECKETT AND MONOLOGUE DRAMA: PERFORMING THE SELF
Authors: WOHL Eugen Radu
Published: December 2018

Samuel Beckett and Monologue Drama: Performing the Self. The paper discusses four of Samuel Beckett’s monologue plays “Krapp’s Last Tape” (1958), “Play” (1964), “Breath” (1969), “Not I” (1972) and “A Piece of Monologue” (1979), with the purpose of delineating their structure and understanding the playwright’s experimental usage of this artistic genre, as well as its role within his overall dramatic corpus. We will attempt a historical and analytical foray into the many uses of the concept of monologue in both literature and theatre, with the intention to clarify its various appropriations in these fields and with the hope of eliciting further research into this important topic of analysis.
Rezumat. Samuel Beckett și monologul teatral: Performarea sinelui. Lucrarea discută monologurile teatrale ale lui Samuel Beckett, “Ultima bandă a lui Krapp” (1958), “Joc” (1964), “Respirație” (1969), “Nu eu” (1972) și “Un fragment de monolog” (1979), cu scopul de a le delimita structura, modul unic prin care dramaturgul înțelege să se raporteze la acest gen dramatic, precum și rolul lor în ansamblul operei lui Beckett. Speranța noastră este ca aceast demers de cercetare a monologului, așa cum e înțeles în literatură și teatru, va reuși să stimuleze cercetări ulterioare asupra acestui subiect de analiză.
Cuvinte cheie: Samuel Beckett, monolog dramatic, drama monologată, discurs fracturat, performance.
Latin American Marine Corps: between the past and the future
Authors: Editorial Comité , Moloesnik Marcos Pablo
Published: December 2018

Latin american marine corps
Nuevas Dinámicas del Poder Naval en el Siglo XXI¬: la competencia por el control y en el espacio marítimo
Authors: Altieri Mariana Alejandra
Published: December 2018

Este artículo estudia la dinámica del poder naval en el contexto internacional del Siglo XXI. En él se analiza de qué forma la competencia por el reacomodamiento de poder mundial, entre los actores statuquistas y revisionistas del sistema internacional, se plasma en la disputa por el ámbito marítimo. Se sostiene que, en el marco de la decadencia de Estados Unidos como poder naval hegemónico y el ascenso de nuevos poderes navales, el espacio marítimo se ha convertido en la gran zona de fractura de este tiempo.
Drones
Authors: Tello Angel Pablo
Published: December 2018

El trabajo se centra en los drones
UPAYA ORANG TUA DALAM MENGANTISIPASI BAHAYA NARKOBA DIKALANGAN REMAJA DESA SALAMBUE KECAMATAN PADANGSIDIMPUAN TENGGARA
Authors: Nasution Nur Cahaya
Published: December 2018

Salambue Village is a village that is quite vulnerable to drug activities. It is evident that dealers, dealers and drug users are increasing and increasing. This study will explore: 1) The Condition of Adolescents Who Misuse Drugs in Salambue Village, 2) Parents' Efforts to Anticipate Narcotics Hazards among Adolescents in Salambue Village II, 3) Parental Obstacles and Challenges in Anticipating Narcotics Hazards in Salambue Sub-District Youth Adolescents Padangsidimpuan Tenggara. This research is qualitative research using descriptive methods. Data collection is done by observation and interview techniques. The results showed that: 1) The Condition of Adolescents Abusing Narcotics in Salambue Village was very alarming because it resulted in psychiatric disorders (crazy), 2) Parents' efforts to anticipate the danger of narcotics among Salambue Villagers included: continuous parental advice, sending their children to school to Pondok Pesantren, punishments that educate, equip children with religious knowledge, children are preoccupied with positive activities, limit child interaction, spend time with children and create comfort in the household so that children feel at home. 3) Obstacles and Challenges of Parents in Anticipating the Dangers of Narcotics in Adolescents Salambue Village, South Padangsidimpuan Subdistrict, is: limited parental time for children, limited parental knowledge about drugs, and village conditions for drug emergency.
Espaços de convivência para idosos: benefícios e estratégias
Authors: Francisco Celia Maria , Abrantes Pinheiro Marcia
Published: December 2018

Os espaços de Convivência para o idoso no Brasil, destina-se ao segmento às pessoas com idade igual ou superior a 60 anos em situação de vulnerabilidade, risco pessoal e social. Assim, o objetivo do estudo foi conhecer os benefícios e as estratégias utilizadas nos Núcleos e Centros de Convivência para idosos. Foi realizada revisão integrativa nas bases SCIELO e LILACS. Para tal foi utilizado os descritores Convivência; Idoso, Isolamento. Os resultados demonstram que os idosos participantes de centro de convivência apresentam melhor equilíbrio, mobilidade funcional e qualidade de vida quando comparados aqueles que não frequentam o espaço. Conclui-se que os espaços de convivência não seja apenas um local para atividade física, lazer, diversão e prevenção a doenças associadas ao processo do envelhecimento, mas sim, um ambiente que contribui para o autonomia, independência e inclusão social da pessoa idosa.
Suicide among veterinarians in the United States from 1979 through 2015
Authors: Tomasi Suzanne E. , Fechter-Leggett Ethan D. , Edwards Nicole T. , Reddish Anna D. , Crosby Alex E. , Nett Randall J.
Published: December 2018

OBJECTIVE To assess proportionate mortality ratios (PMRs) for suicide among male and female US veterinarians from 1979 through 2015.

DESIGN PMR study.

SAMPLE Death records for 11,620 veterinarians.

PROCEDURES Information for veterinarians who died during 1979 through 2015 was obtained from AVMA obituary and life insurance databases and submitted to a centralized database of US death records to obtain underlying causes of death. Decedent data that met records-matching criteria were imported into a software program for calculation of PMRs for suicide stratified by sex and indirectly standardized for age, race, and 5-year calendar period with 95% confidence intervals.

RESULTS 398 deaths resulted from suicide; 326 (82%) decedents were male, 72 (18%) were female, and most (298 [75%]) were ≤ 65 years of age. The PMRs for suicide for all veterinarian decedents (2.1 and 3.5 for males and females, respectively), those in clinical positions (2.2 and 3.4 for males and females, respectively), and those in nonclinical positions (1.8 and 5.0 for males and females, respectively) were significantly higher than for the general US population. Among female veterinarians, the percentage of deaths by suicide was stable from 2000 until the end of the study, but the number of such deaths subjectively increased with each 5-year period.

CONCLUSIONS AND CLINICAL RELEVANCE Results of the study indicated that PMRs for suicide of female as well as male veterinarians were higher than for the general population. These data may help to inform stakeholders in the creation and implementation of suicide prevention strategies designed for veterinarians.
Entomological and sociobehavioral components of heartworm (Dirofilaria immitis) infection in two Florida communities with a high or low prevalence of dogs with heartworm infection
Authors: Ledesma Nicholas A. , Kaufman Phillip E. , Xue Rui-De , Leyen Christopher , Macapagal Mark J. , Winokur Olivia C. , Harrington Laura C.
Published: December 2018

OBJECTIVE To assess knowledge, attitudes, and practices regarding heartworms (Dirofilaria immitis) and mosquito vectors among residents (dog owners and non-dog owners) in 2 neighborhoods in Florida and to perform entomological surveys of mosquito species in these neighborhoods and identify mosquito species infected with heartworm.

DESIGN Cross-sectional study.

SAMPLE 2,572 mosquitoes and 96 residents of 2 northern Florida communities.

PROCEDURES A 32-item questionnaire was orally administered to a convenience sample of community residents to collect information on their knowledge, attitudes, and practices regarding heartworms. Afterward, mosquito larvae were collected from the respondents' properties and adult mosquitoes were collected in both communities from surrounding wooded areas and residences of respondents. Mosquito species distribution and D immitis infection rates were determined.

RESULTS Many residents (59% [57/96]) were unaware that mosquitoes transmit heartworms. Compared with non-dog owners, dog owners were significantly more likely to know about mosquito transmission, be concerned about heartworms, accurately estimate cost of treatment, and demonstrate willingness to pay for treatment. Most owners (71% [47/66]) administered heartworm preventives; those who did not cited lack of risk awareness, and cost was the least common reason. Of 28 mosquito species collected, Anopheles quadrimaculatus, Culex erraticus, Culex nigripalpus, Coquillettidia perturbans, Culiseta inornata, Aedes albopictus, and Aedes aegypti were positive for D immitis infection.

CONCLUSIONS AND CLINICAL RELEVANCE Findings suggested that improved veterinary and public health messaging regarding the role of mosquitoes as vectors, higher cost of heartworm treatment versus prevention, and mosquito reduction and avoidance methods is needed.
Activated carbons by zinc chloride activation for dye removal – a commentary
Authors: Hock Pua Eng , Zaini Muhammad Abbas Ahmad
Published: December 2018

Zinc chloride is a commonly used activator in chemical activation of activated carbon. Various carbonaceous materials have been studied as potential source of activated carbon. The operating conditions are manipulated with attention to improve the properties and performance of activated carbon in the adsorption of water pollutants. However, the generalized attributes of zinc chloride activation in relation to the adsorptive performance of activated carbon are not well documented in much of published literature. Therefore, the present work is aimed to highlight the activation strategies and mechanisms of zinc chloride activation of activated carbon. The roles of impregnation ratio, period of activation and temperature are discussed to offer some insight into textural characteristics of activated carbon. The case studies on methylene blue adsorption are integrated to shed light on the external factors affecting the adsorption.
An overview of main arsenic removal technologies
Authors: Zakhar Ronald , Derco Ján , Čacho František
Published: December 2018

Arsenic (As) is metalloid, naturally present in the environment but also introduced by human activities. It is toxic and carcinogenic and its exposure to low or high concentrations can be fatal to human health. Arsenic contamination in drinking water threatens more than 150 million peoples all over the world. Therefore, treatment of As contaminated water is of unquestionable importance. The present review begins with an overview of As chemistry, distribution and toxicity, which are relevant aspects to understand and develop remediation techniques. The most common As removal processes (chemical precipitation, adsorption, ion exchange, membrane filtration, phytoremediation and electrocoagulation) are presented with discussion of their advantages, drawbacks and the main recent achievements.
Batch drying of sliced tomatoes at specific ambient conditions
Authors: Royen Mohammad Jafar , Noori Abdul Wasim , Haydary Juma
Published: December 2018

In this work, drying of tomato slices was studied in a laboratory scale batch dryer working at conditions specific for geographical locations with low ambient pressure and low relative humidity of air. Tomato is a perishable farm product with high moisture content. Despite their high value, tomatoes are subjected to wastage and spoilage during their seasonal period; to last longer after harvested, they need to be treated by drying. Drying is one of the most widely used methods of tomato preserving for a longer period of time. This study involves experimental work on tomatoes drying in a tray laboratory batch dryer with the dimensions of (490 × 330 × 310) mm, a load cell-force sensor (range: 0–5 kg), fan (speed: 0–2500 rpm), air flow sensor (0–150 l/min) and a temperature and humidity monitoring system. This study was aimed at the development of a suitable drying method for the production of dehydrated agricultural products under specific air properties and climate conditions such as low ambient pressure and low relative humidity. During the experiment, the average ambient pressure was 82 kPa, and the average relative humidity of air was 20 %. Drying characteristics of tomato slices were determined at three temperature levels, namely: 50 °C, 60 °C and 70 °C,and three air flow rates: 30 l/s, 40 l/s and 50 l/s, for each temperature level. In this study, the effect of temperature, air flow rate, and ambient conditions on the drying rate of tomato slices were studied. The results indicate that during the experiments, tomatoes were dried to the final moisture content of 32.2 % from 92 %. Drying time at 50 °C, 60 °C and 70°C, and air flow of 30 l/s was 17.80 h, 15.80 h, and 14.08 h, respectively. For the air flow rate of 40 l/s, the drying time was 15.0 h, 12.9 h and 11.7 h and for the air flow rate of 50 l/s, the drying time of tomato slices was 14.0 h, 11.6 h and 10.2 h, respectively.
Design of operational temperature for immobilized glucose isomerise using an accelerated inactivation method
Authors: Illeová Viera , Polakovič Milan
Published: December 2018

Thermal inactivation of immobilized glucose isomerase in a concentrated glucose solution was investigated in the batch mode and temperature range of 83–95 °C, which is substantially higher than the temperature used in the industrial production of high-fructose corn syrup. Simultaneous evaluation of all inactivation data showed that first-order kinetics with the Arrhenius temperature dependence of the rate constant provided a good approximation of the biocatalyst stability under the investigated conditions. The model parameters were then used to predict the operational temperature for this biocatalyst in the production of high-fructose corn syrup based on the set operational life-time of the biocatalyst. The simulation predicted a window of operational temperature of 60–65 °C, which corresponds very well with the industrial applications of this biocatalyst. This observation demonstrates that the multi-temperature method of enzyme inactivation can provide a good estimate of biocatalyst process stability and is thus a useful tool in the development of biocatalytic processes.
Comparative Assessment of uNGAL, uNAG and Cystatin C As Early Biomarkers in Renal Post-Transplant Patients
Authors: Nikolov G. , Boncheva M. , Gruev T. , Trajkovska K. T. , Kostovska I.
Published: December 2018

Urinary neutrophil gelatinase-associated lipocalin (uNGAL), urinary N-acetyl-bd-glucosaminidase (NAG), urinary α1-microglobulin/creatinine ratio and cystatin C have been suggested as potential early markers of delayed graft function (DGF) following kidney transplantation. We conducted a prospective study in 50 consecutive kidney transplant recipients to evaluate serial changes of these biomarkers within the first week after transplantation and assess their performance in predicting DGF (dialysis requirement during initial post-transplant week) and graft function throughout the first year. Urine samples were collected on post-transplantation days 0, 1, 2, 4, and 7. Statistical analysis: Linear mixed and multivariable regression models, receiver-operating characteristic (ROC), and areas under ROC curves were used. At all-time points, mean urinary NGAL levels were significantly higher in patients developing DGF. Shortly after transplantation (3-6 h), uNGAL and uNAG values were higher in DGF recipients (on average +242 ng/mL; NAG – 6.8 U/mmol creatinine, considering mean dialysis time of 4.1 years) and rose further in the following days, contrasting with prompt function recipients. On Day-1 uNGAL levels accurately predicted DGF (AUC-ROC = 0.93), with a performance higher than serum creatinine (AUC-ROC = 0.76), and similar to cystatin C (AUC-ROC = 0.95). Multivariable analyses revealed that uNGAL levels at days 4 and 7 were strongly associated with one-year serum creatinine level. Urinary NGAL, serum cystatin C is an early marker of graft injury and is independently associated with dialysis requirement within one week after transplantation and one-year graft function.
Patients’ Satisfaction as a Tool of Dental Setting and Dental Services Assessment in the Dental College of Mangalore
Authors: Shetty A. , Hegde P. , Madiyal A. , Bhandary R. , Thomas B.
Published: December 2018

Provision of quality health services to population of the rural areas with limited access to dental treatment and educating dental students in high standard of professional conduct when delivering health services to the population, represents the main reason for the foundation of a dental college in an area like Mangalore. The purpose of this study was to assess the satisfaction of patients visiting the dental college clinics. A cross-sectional study was conducted between May 1 and July 31, 2017. A questionnaire, covering 4 items: patient-dentist relationship; efficiency of the general clinic; patients perception of dental care quality; college healthcare opinion, was distributed to 400 patients visiting the dental clinic. Data were treated statistically using overall percentage distributions and Fisher exact test. The mean percentage of agreement for the 4 items was 85.86 ± 24.51% denoting a high level of satisfaction. Fisher exact test showed (p < 0.01) statistically important difference between first time and multiple time visitors answers. Majority of the patients were satisfied with the clinical settings and the benefits of the fast delivered treatment. The quality of the services was appreciated by the majority of visitors. The attitude of the providers of healthcare was perceived as very friendly and gentle. The assessment of patients’ contentment and perception of healthcare services could be an efficient tool to evaluate the overall activity of an educational healthcare institution.
Toward an evaluation model for transnational cooperation activities in rural areas: a case study within an EU LEADER project
Authors: De Luca Anna Irene , Iofrida Nathalie , Gulisano Giovanni , Strano Alfio
Published: December 2018

Cooperation activities between Local Action Groups (LAGs) have been introduced into EU LEADER (Liaison Entre Actions de Développement de l’Économie Rurale) initiative to provide rural areas the opportunity to exchange experiences and best practices, as well as to realize common activities by pooling human and financial resources. The main purposes are to overcome isolation and add value to local development strategies. The benefits of cooperation are widely recognized but, undeniably, it can be also a difficult and time-consuming process. For this reason, evaluation is a necessary tool to measure the success of cooperation and to help actors address their strategies for the future. In this paper, an evaluation methodology is proposed and applied to an EU LEADER+ case study, the ‘Integrated Project for Rural Tourism: Environment and Qualified Hospitality’, a transnational cooperation experience led by LAG Aspromar, based in the province of Reggio Calabria, Southern Italy. Quantitative and qualitative data have been collected through the integration of three typical methods of social research: two techniques based on surveys, namely interviews with privileged actors, and a semi-structured questionnaire, and a technique based on non-survey data and the study of documents. Results can be useful to highlight pros and cons of the management of a cooperation project and to stimulate projects’ leaders on activating improvement processes.
Adventure Tourism Motivations: A push and pull factor approach
Authors: Giddy Julia K.
Published: December 2018

The increased growth and commercialization of adventure tourism led to a number of changes in the profile of the individuals who now engage in adventure activities. As a result, previous understandings of adventure tourism motivations may no longer be valid. This study seeks to investigate the influence of these changes by analyzing the motivations of tourists who have engaged in adventure tourism across a range of commercial adventure activities. This is done through data collected from participants in adventure tourism, throughout South Africa, using a push and pull factor approach to motivations. The results show the increasing influence of the experiences with nature in motivations, particularly in the context of pull factors. The role of risk and thrill in motivations, which has been emphasized in previous literature, is found to be relatively minimal among these respondents. Furthermore, adventure tourism experiences are found to be dynamic, with an increasing number of significant factors influencing decision-making. It also demonstrates notable differences in the motivations of participants, based on the type of activity in which they engage.
Dynamics of regional disparities in Slovakia in 2001 and 2011
Authors: Michálek Anton , Podolák Peter , Madajová Michala Sládeková
Published: December 2018

This paper is focused on the presentation of developmental tendencies of regional disparities in Slovakia in 2001 and 2011 from the point of view of selected and relevant socio-economic and demographic indicators. To test the divergence hypothesis of the regional disparities at a district level, these are evaluated by using multidimensional analysis of 14 indicators. The overall level and development of regional disparities are measured with the help of the methods of descriptive statistics and multi-criteria assessments (integrated index). The results confirm the hypothesis of divergence development as the basic tendency of regional development in Slovakia. The presented research has documented evident time shortening of significant changes in regions drifting towards divergent development. Rapid and, up to now, unprecedented changes (employment and wages growth, enterprise development, foreign investments increase, etc.), are evident and reflected in the majority of indicators – however, with different impacts on the regional level.