bluuebunny/crossref_metadata_2025 huggingface dataset:
Vestir al otro en el Caribe. Ropas para indios y pobres
Authors: Valcárcel Rojas Roberto
Published: November 2017

La desnudes indígena fue enfrentada desde el proyecto de evangelización y civilización desplegado por España en el Nuevo Mundo. No solo se trató de una supuesta confrontación ética y moral sino de un acto de dominación en el que imponer la norma de vestir a los indígenas, servía para atacar sus identidades originarias y construir un nuevo ser, el indio. El uso y comercio de la ropa de segunda mano funciona varios siglos después como un recurso de señalización y explotación de la pobreza. En este texto reflexiono sobre estos dos momentos donde la ropa sirve para construir la identidad y naturaleza de los subordinados, y apuntar sobre la ubicación marginal del Caribe en los diseños de estructuración del poder global. A través del análisis histórico sobre manejo de ropa entre indígenas de las Antillas Mayores, y la vivencia antropológica en espacios comerciales de la ciudad de Santo Domingo, República Dominicana, se constata la reiteración de los mecanismos de dominio y el papel central de la cultura material en estos.
Perbaikan tanah melalui mediasi hayati [Bio-mediated soil improvement]
Authors: GOENADI Didiek H
Published: November 2017

Soil properties unsuitable to support physical requirements oftenly become problems in utilizing it for agricultural as well as construction purposes.  Most common practice to overcome the problems is by applying chemical agent which are not only expensive but also un-enviromentally friendly.  Therefore, it is imperative to seek a new, sustainable, and innovative technology to improve mechanical soil properties.  Many researches gave opportunity to utilize microbes for this idea.  However, the direct application of this technology faces some handicaps in the field, i.e. soil and pore fluid interaction, bio-augmentation verses bio-stimulation of microbial community, controlled distribution of bio-mediated calcite precipitation, and permanence cementation.  This article aims at providing a general overview regarding technological development to improve soil mechanical properties suitable for construction by applying microbes.
Problems in Student Teaching
Authors: Soslau Elizabeth , Raths James
Published: November 2017

Currently, education schools across the nation are reforming teacher education programs in light of the newly developed common core standards, shifting accreditation principles, new measures of teacher performance, and the pressing concern that in-service teachers are woefully under-prepared for the realities of classrooms. During this time of wide spread programmatic reform, we present a list of considerations that are particularly germane to the clinical preparation of student teachers. Our list includes common practices that limit learning opportunities for student teachers and detract from the meaningfulness of assessing student teachers. We posit three approaches for education schools to consider as they engage in program revisions.
The Experiences of Low German-Speaking Mennonite Men in Alternative Education Programs in Southwestern Ontario
Authors: Brubacher Cameron , Wilson-Forsberg Stacey
Published: November 2017

The tradition of leaving high school and finding full-time employment after grade 8 has put Low German-speaking (LGS) Mennonites in rural Southwestern Ontario in a vulnerable economic position. Consequently, alternative education programs have been developed by Ontario public school boards in areas containing high numbers of LGS Mennonites. The programs strive to keep LGS Mennonite youth in school by creating spaces where primarily male LGS Mennonite students feel more comfortable and can pursue a high school diploma while maintaining their religious beliefs, cultural identity, and work responsibilities. This article draws from qualitative interview data and open-ended survey responses to explore perceptions of LGS Mennonite men’s experiences in alternative education programs, and it highlights factors that caused the men to avoid or leave the programs. This article offers recommendations on how to strengthen the programs to increase the number of LGS Mennonite students attending them. It emphasizes the importance of LGS Mennonite students receiving strong messages from educators that their language, culture, and religious beliefs are valued even if that means separating the youth from Canadian society rather than integrating them on equal terms to minimize their marginalization.
Study of multivariate analysis of quantitative traits in Iranian pumpkin lines
Authors: Yadegari Mehrab , Ansari Mohammad
Published: November 2017

In this study, seed yield production and its different components fruit
length, fruit diameter, fruit length/fruit diameter ratio (FL/FD), diameter
of flesh, diameter of seed core, fruit weight, weight of 1000 seed from 24
lines of pumpkin grown in Iran was examined. Twenty-five characters in all
plant lines were measured by Descriptor (UPOV) and data were subjected to
cluster analysis. Results showed that plants lines were divided in four
groups. In all groups, regression comparisons were made for modeling the
effect of different characters on seed yield, results also showed that fruit
weight and fruit length in all groups had the most direct effect on seed
yield. In conclusion, these traits are suggested as the best indirect
selection criteria to improve the seed yield genetically in Cucurbita spp.
genotypes especially in preliminary generation of breeding and selection
programs.
Evaluation of reciprocal cross populations for spike-related traits in early consecutive generations of bread wheat (Triticum aestivum L.)
Authors: Kutlu Imren , Balkan Alpay , Korkut Kayıhan , Bilgin Oguz , Baser Ismet
Published: November 2017

Breeding effort on increasing grain yield of wheat will incessantly continue
because it is indispensable product. Obtaining the genetic information such
as genotypic variation, heritability, genetic advance is the fundamental
components of these studies. It is important that the maternal effects are
put forward throughout successive generations because of genotypic and/or
environmental effects as far as variation. This research was conducted to
investigate changes of reciprocal crosses throughout successive generations
and determine selection criteria for high yield in early generations. For
this purpose, the populations were analyzed with regard to genotypic and
phenotypic variation coefficient, heritability, genetic advance and
Unweighted Pair Group Method (UPGMA) cluster analysis for real crosses,
reciprocals and all genotypes separately. According to the results,
heritability and genetic advance values of traits investigated were highly
varied throughout successive generations among real crosses, reciprocals and
all genotypes. This finding indicated that non-additive gen effects or
epitasis played a role in inheritance of all traits. Dissimilarity of
crosses than their reciprocals indicated variation of successive generation.
Dissimilarity value of each parent differed as generation progresses
according to combination created. This condition suggested that there were
maternal effects in this population throughout successive generations. Grain
weight per spike, spike harvest index and spike density had high direct and
indirect effects on the grain yield at all of three generations, it proved
that these traits can be a selection criterion for early generations. Sana
was the best parent and ?Bezostaja x Krasunia? and ?Krasunia x Pehlivan?
were best performance in most of traits at all generations.
Morphological variability of Quercus robur L. leaf in Serbia
Authors: Batos Branislava , Miljkovic Danijela , Perovic Marko , Orlovic Sasa
Published: November 2017

This paper presents the results of a study dealing with leaf morphological
variability of Quercus robur L. 148 trees were sampled from 5 population
across Serbia and 17 morphological traits were assessed. Interpopulation
variability was confirmed by the results of the analysis of variance (ANOVA).
A statistically significant (p <0.05) effect of population was obtained for
most of the studied morphological characters. Intrapopulation variability was
confirmed by statistically significant tree effects for all of the studied
leaf characters (all p < 0.05). The results of the multivariate analysis of
variance (MANOVA) confirmed a significant population and tree share in the
total phenotypic variability (all p <0.05). By applying the canonical
discriminant analysis (CDA), the first discriminant function accounted for
63% of the variability between populations and the second accounted for 20%
of the population variability. The leaf area (AREA), specific leaf area (SLA)
and surface area to perimeter ratio (ARPE) had the greatest effect on
population differentiation (CDA). It is assumed that different environmental
conditions affect population differentiation and that high intrapopulation
variability is due to intraspecific variability.
Genetic structure and diversity of European chestnut (Castanea sativa Mill.) populations in western Balkans: On a crossroad between east and west
Authors: Skender Azra , Kurtovic Mirsad , Pojskic Naris , Kalamujic-Stroil Belma , Hadziabulic Semina , Gasi Fuad
Published: November 2017

European chestnut (Castanea sativa Mill.) is highly valued in the western
Balkans as a source of timber and fruit, but also as an important source of
nectar and pollen for the production of honey. In this study, four chestnut
populations, covering a major portion of the western Balkans, and a
reference population from the northern Italy were examined using 21
microsatellite markers. The highest genetic diversity was detected within
the populations geographically closest to the Italian Peninsula, which also
displayed the highest level of admixture with the samples from Italy. The
strongest genetic differentiation was noted among the southern and eastern
chestnut populations from Bosnia and Herzegovina (B&H) (Gst=12.05%). This
pronounced differentiation is probably caused by the genetic adaptations to
notably different climatic conditions present in the south (Mediterranean
climate) and east (Continental climate) of B&H. The clear genetic
differentiation of the southern and eastern B&H chestnut populations from
the Italian population, determined by pairwise Gst, FCA and Bayesian
Structure analyses, indicates that these populations most likely originated
from independent shelter zones (refugia), after the last glaciation period.
Based on these results we propose a presence of an introgression zone in the
northwestern Balkans, established through gene flow from the Italian and the
Balkan Peninsula. The obtained insights into the structure of all analyzed
populations will significantly contribute towards establishing a regional
conservation and utilization strategy for European chestnut in western
Balkans.
Relationship between genetic diversity and cold-tolerance of maize inbred lines
Authors: Milivojevic Marija , Nikolic Ana , Markovic Ksenija , Filipovic Milomir , Vancetovic Jelena , Petrovic Tanja , Srdic Jelena
Published: November 2017

Early maize sowing enables longer growing season with enhanced possibility of
achieving higher and more stable yields, and better chances of avoiding
summer droughts. For early sowing, cold-tolerant maize genotypes should be
used. Breeding maize, tolerant to low temperatures, requires knowledge of
genetic diversity and heterotic patterns of breeding material. The objective
of this study was to determine genetic diversity of 15 ZP maize inbred lines
applying the method of protein markers (UTLIEF method), and to establish
correspondence between thus obtained classification with the results of cold
test (CT) and field emergence (FE). During two production seasons (2011 and
2014), 15 maize inbred lines were self-pollinated. Pedigree data showed that
material belongs to different maturity and heterotic groups. Cold tolerance
was assessed in laboratory (2015) by cold test (7.5 ?C, 10 days), and field
trials on two locations during two successive years (2015, 2016). ZP maize
inbred lines showed very good response to stressful conditions of CT and FE.
Inbred lines with Lancaster background were more sensitive to low
temperatures than inbred lines with BSSS and Iowa Dent background. Based on
UTLIEF method two inbred lines with Lancaster background (ZPL 5 and ZPL 7)
were grouped by cluster analysis together with Iowa Dent inbred lines, that
also expressed better cold tolerance, and thus exceptional consent was
achieved with the results of CT and FE. Classification of maize inbred lines
based on UTLIEF method, followed by cluster analysis and PCA, showed good
agreement with pedigree data, which points out that this method could be
successfully applied for genetic classification of breeding material of a
wide genetic background.
Regression tree analysis for predicting body weight of Nigerian Muscovy duck (Cairina moschata)
Authors: Oguntunji Abel
Published: November 2017

Morphometric parameters and their indices are central to the understanding of
the type and function of livestock. The present study was conducted to
predict body weight (BWT) of adult Nigerian Muscovy ducks from nine (9)
morphometric parameters and seven (7) body indices and also to identify the
most important predictor of BWT among them using regression tree analysis
(RTA). The experimental birds comprised of 1,020 adult male and female
Nigerian Muscovy ducks randomly sampled in Rain Forest (203), Guinea Savanna
(298) and Derived Savanna (519) agro-ecological zones. Result of RTA
revealed that compactness; body girth and massiveness were the most
important independent variables in predicting BWT and were used in
constructing RT. The combined effect of the three predictors was very high
and explained 91.00% of the observed variation of the target variable (BWT).
The optimal regression tree suggested that Muscovy ducks with compactness
>5.765 would be fleshy and have highest BWT. The result of the present study
could be exploited by animal breeders and breeding companies in selection
and improvement of BWT of Muscovy ducks.
Testing and incorporating additional determinants of ethics in counterfeiting luxury research according to the theory of planned behavior
Authors: Zaman Syed , Jalees Tariq , Jiang Yushi , Kazmi Syed
Published: November 2017

Counterfeiting is a worldwide issue. In order to resolve the counterfeiting problem, a new holistic model is developed containing 17 constructs. This empirically tested model is grounded on Theory of Reasoned Action and Theory of Planned Behaviour. The valid sample size for the study is 907 with a response rate of 95%. After preliminary analysis, the model is developed and tested in two stages. Initially, of each construct, CFA is tested followed by testing of the overall model. The model (H1) developed and empirically tested, adequately explains consumer attitude and behaviour. Attitude (H5) is the strongest predictor of purchase intention. Additionally, moral orientation (H4) is the strongest predictor of attitude, followed by personal orientation (H3) and social orientation (H2). In the case of sub-factors of social orientation, individualism (H2D) is the strongest predictor of attitude followed by informative (H2B) and collectivism (H2C). Normative (H2D) is not tested and dropped while fitting into the model. On the other hand, in the case of personal orientation, perceived risk (H3C) has no effect on attitude. Whereas personal gratification (H3E) has the strongest effect on attitude followed by materialism (H3D), status consumption (H3A) and value consciousness (H3B). Similarly, In the case of moral orientation (H4B) only Relativism is validated. The other three hypotheses on idealism (H4A) religiosity (H4C) and ethics (H4D) though having significant effects are rejected as all of these effects are positive as compared to what is hypothesised. It is also found that effect of attitude towards purchase is universal and does not vary from one product category to other. However, the rest of subfactors effects differ from one culture to other and from one product to another.
Long-term Trends in Antidiabetes Drug Usage in the U.S.: Real-world Evidence in Patients Newly Diagnosed With Type 2 Diabetes
Authors: Montvida Olga , Shaw Jonathan , Atherton John J. , Stringer Frances , Paul Sanjoy K.
Published: November 2017

OJBECTIVE

To explore temporal trends in antidiabetes drug (ADD) prescribing and intensification patterns, along with glycemic levels and comorbidities, and possible benefits of novel ADDs in delaying the need for insulin initiation in patients diagnosed with type 2 diabetes.

RESEARCH DESIGN AND METHODS

Patients with type 2 diabetes aged 18–80 years, who initiated any ADD, were selected (n = 1,023,340) from the U.S. Centricity Electronic Medical Records. Those who initiated second-line ADD after first-line metformin were identified (subcohort 1, n = 357,482); the third-line therapy choices were further explored.

RESULTS

From 2005 to 2016, first-line use increased for metformin (60–77%) and decreased for sulfonylureas (20–8%). During a mean follow-up of 3.4 years post metformin, 48% initiated a second ADD at a mean HbA1c of 8.4%. In subcohort 1, although sulfonylurea usage as second-line treatment decreased (60–46%), it remained the most popular second ADD choice. Use increased for insulin (7–17%) and dipeptidyl peptidase-4 inhibitors (DPP-4i) (0.4–21%). The rates of intensification with insulin and sulfonylureas did not decline over the last 10 years. The restricted mean time to insulin initiation was marginally longer in second-line DPP-4i (7.1 years) and in the glucagon-like peptide 1 receptor agonist group (6.6 years) compared with sulfonylurea (6.3 years, P < 0.05).

CONCLUSIONS

Most patients initiate second-line therapy at elevated HbA1c levels, with highly heterogeneous clinical characteristics across ADD classes. Despite the introduction of newer therapies, sulfonylureas remained the most popular second-line agent, and the rates of intensification with sulfonylureas and insulin remained consistent over time. The incretin-based therapies were associated with a small delay in the need for therapy intensification compared with sulfonylureas.
Genetic testing in translational ophthalmology
Authors: Abeshi Andi , Precone Vincenza , Beccari Tommaso , Dundar Munis , Falsini Benedetto , Bertelli Matteo
Published: November 2017

Inherited eye diseases are a group of conditions with genetic and phenotypic heterogeneity. Advances in ocular genetic research have provided insights into the genetic basis of many eye diseases. Genetic and technological progress is improving the management and care of patients with inherited eye diseases. Diagnostic laboratories continue to develop strategies with high specificity and sensitivity that reduce the costs and time required for genetic testing. The introduction of next generation sequencing technologies has significantly advanced the identification of new gene candidates and has expanded the scope of genetic testing. Gene therapy offers an important opportunity to target causative genetic mutations. There are clinical trials of treatments involving vector-based eye gene therapies, and a significant number of loci and genes now have a role in the diagnosis and treatment of human eye diseases. Applied genetic technology heralds the development of individualized treatments, ushering ophthalmology into the field of personalized medicine. Many therapeutic strategies have demonstrated efficacy in preclinical studies and have entered the clinical trial phase. In this paper we review the topic of genetic testing in inherited eye diseases. We provide some background information about genetic counseling and genetic testing in ophthalmology and discuss how genetic testing can be helpful to patients and families with inherited eye diseases.
Pharmacologically active fractions of Sideritis spp. and their use in inherited eye diseases
Authors: Abeshi Andi , Precone Vincenza , Beccari Tommaso , Dundar Munis , Falsini Benedetto , Bertelli Matteo
Published: November 2017

The main constituents of the genus Sideritis are various terpenoids, sterols, coumarins, flavonoid aglycones and glycosides. Sideritis species have been traditionally used as infusions or flavoring agents and in medicine as anti-inflammatory, antiulcer, antimicrobial, antioxidant, antispasmodic and analgesic agents. This paper includes the following sections: Introduction, Description and distribution of Sideritis spp, Pharmacological effects, Toxicity tests, Rationale for use of Sideritis spp. in ophthalmology and Conclusions. The aim is to provide a comprehensive overview on the botanical, phytochemical and pharmacological aspects of the genus Sideritis, and to establish the scientific basis of its pharmacological use. New approaches to using officinal plants have recently yielded significant results. The paper also reviews this information and provides a critical view on the options for exploiting the potential of Sideritis spp. in ophthalmology.
Genetic testing for Bietti crystalline dystrophy
Authors: Abeshi Andi , Bruson Alice , Beccari Tommaso , Dundar Munis , Ziccardi Lucia , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for Bietti crystalline dystrophy (BCD). The disease has autosomal recessive inheritance, a prevalence of 1 per 67 000, and is caused by mutations in the CYP4V2 gene. Clinical diagnosis is based on clinical findings, ophthalmological examination, electroretinography and optical coherence tomography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for central areolar choroidal dystrophy
Authors: Abeshi Andi , Fanelli Francesca , Beccari Tommaso , Dundar Munis , Falsini Benedetto , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for central areolar choroidal dystrophy (CACD). CACD is mostly inherited in an autosomal dominant manner. Transmission is rarely autosomal recessive. Overall prevalence is currently 1-9 per 100 000. CACD is caused by mutations in the PRPH2 and GUCY2D genes. Clinical diagnosis is based on clinical findings, ophthalmological examination, fluorescein angiography, electroretinography (showing cone dystrophy) and stereo fundus photography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for corneal dystrophies and other corneal Mendelian diseases
Authors: Abeshi Andi , Fanelli Francesca , Beccari Tommaso , Dundar Munis , Viola Francesco , Colombo Leonardo , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for corneal dystrophies and other Mendelian corneal diseases (CDs). CDs are mostly inherited in an autosomal dominant manner (autosomal recessive inheritance is rare). The overall prevalence is currently unknown. CDs are caused by mutations in the AGBL1, CHST6, COL8A2, DCN, GSN, KRT12, KRT3, NLRP1, PAX6, PIKFYVE, PRDM5, SLC4A11, TACSTD2, TCF4, TGFBI, UBIAD1, VSX1, ZEB1, and ZNF469 genes. Clinical diagnosis is based on clinical findings, ophthalmological examination, confocal microscopy and slit-lamp biomicroscopy. The genetic test is useful for confirming diagnosis and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for Doyne honeycomb retinal dystrophy
Authors: Abeshi Andi , Coppola Pamela , Beccari Tommaso , Dundar Munis , Ziccardi Lucia , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Doyne honeycomb retinal dystrophy (DHRD). The disease has an autosomal dominant inheritance and is caused by variations in the EFEMP1 gene. There is insufficient data to establish the prevalence of DHRD. Clinical diagnosis is based on clinical findings, ophthalmological examination, electroretinography, fluorescein angiography and optical coherence tomography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for Mendelian myopia
Authors: Abeshi Andi , Coppola Pamela , Beccari Tommaso , Dundar Munis , Colombo Leonardo , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Mendelian myopia (MM), a large and heterogeneous group of inherited refraction disorders. Variations in the SLC39A5, SCO2 and COL2A1 genes have an autosomal dominant transmission, whereas those in the LRPAP1, P3H2, LRP2 and SLITRK6 genes have autosomal recessive transmission. The prevalence of MM is currently unknown. Clinical diagnosis is based on clinical findings, family history, ophthalmological examination and other tests depending on complications. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for ocular albinism and oculocutaneous albinism
Authors: Abeshi Andi , Marinelli Carla , Beccari Tommaso , Dundar Munis , Falsini Benedetto , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for ocular albinism and oculocutaneous albinism. Ocular albinism has X-linked recessive inheritance, with a prevalence that varies from 1/40000 to 1/1000000, and is caused by mutations in the GPR143 and CACNA1F genes. Oculocutaneous albinism has autosomal recessive inheritance, with an overall prevalence of 1/17000, and is caused by mutations in the TYR, OCA2, TYRP1, SLC45A2, SLC24A5 and C10orf11 genes. Clinical diagnosis involves ophthalmological examination, testing of visually evoked potentials (VEP) and electrophysiological testing (ERG). The genetic test is useful for confirming diagnosis, differential diagnosis, for couple risk assessment and access to clinical trials.
Genetic testing for optic atrophy
Authors: Abeshi Andi , Bruson Alice , Beccari Tommaso , Dundar Munis , Falsini Benedetto , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for optic atrophy (OA). OA is mostly inherited in an autosomal dominant manner, rarely in an autosomal recessive manner, with an overall prevalence of 3/100,000 live births. It is caused by mutations in the OPA1, OPA3 and TMEM126A genes. Clinical diagnosis is based on clinical findings, ophthalmological examination, OCT, visual evoked potentials (VEPs) and electroretinography. The genetic test is useful for confirming diagnosis, differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for Refsum disease
Authors: Abeshi Andi , Zulian Alessandra , Beccari Tommaso , Dundar Munis , D’Esposito Fabiana , Bertelli Matteo
Published: November 2017

We reviewed the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Refsum disease. The disease has autosomal recessive inheritance, unknown prevalence, and is caused by variations in PEX7 and PHYH genes. Clinical diagnosis is based on clinical findings, ophthalmological examination, electroretinography, optical coherence tomography and phytanic acid assay. The genetic test is useful for confirming diagnosis, for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for non syndromic retinitis pigmentosa
Authors: Abeshi Andi , Bruson Alice , Beccari Tommaso , Dundar Munis , D’Esposito Fabiana , Bertelli Matteo
Published: November 2017

We reviewed the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for non syndromic retinitis pigmentosa (NSRP). NSRP is determined by variations in the ABCA4, AGBL5, ARL2BP, ARL6, BBS2, BEST1, C2orf71, C8orf37, CA4, CDHR1, CERKL, CLRN1, CNGA1, CNGB1, CRB1, CRX, DHDDS, EYS, FAM161A, FSCN2, GUCA1B, HGSNAT, IDH3B, IFT140, IFT172, IMPDH1, IMPG2, KIZ, KLHL7, LRAT, MAK, MERTK, NEK2, NR2E3, NRL, OFD1, PDE6A, PDE6B, PDE6G, POMGNT1, PRCD, PROM1, PRPF3, PRPF31, PRPF4, PRPF6, PRPF8, PRPH2, RBP3, RDH12, RGR, RHO, RLBP1, ROM1, RP1, RP2, RP9, RPE65, RPGR, SAG, SEMA4A, SLC7A14, SNRNP200, SPATA7, TOPORS, TTC8, TULP1, USH2A, ZNF408 and ZNF513 genes. Its overall prevalence is 1 per 4000. It is mostly inherited in an autosomal recessive manner, fewer genes have autosomal dominant or X-linked recessive transmission. Clinical diagnosis is based on clinical findings, ophthalmological examination, best corrected visual acuity (BCVA), slit lamp biomicroscopy, fundus autofluorescence, electroretinography, color vision testing and optical coherence tomography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for Usher syndrome
Authors: Abeshi Andi , Bruson Alice , Beccari Tommaso , Dundar Munis , Colombo Leonardo , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Usher syndrome (USH). USH is mostly transmitted in an autosomal recessive manner and is caused by variations in the ADGRV1, CDH23, CIB2, CLRN1, HARS, MYO7A, PCDH15, PDZD7, USH1C, USH1G, USH2A, WHRN genes. Prevalence is estimated to be 1:30,000. Clinical diagnosis is based on audiogram, vestibular tests, visual acuity test, fundus examination, color test, optical coherence tomography and electroretinography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Genetic testing for X-linked juvenile retinoschisis
Authors: Abeshi Andi , Bruson Alice , Beccari Tommaso , Dundar Munis , D’Esposito Fabiana , Bertelli Matteo
Published: November 2017

We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for X-linked juvenile retinoschisis (XJR). The disease has X-linked inheritance, a prevalence that varies from one in 5000 to one in 25000 males, and is caused by mutations in the RS1 gene. Clinical diagnosis is based on clinical findings, ophthalmological examination, electroretinography and optical coherence tomography. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.
Envelopment and environment. Frame of globalization and crisis
Authors: Tabieres María Susana
Published: November 2017

Envelopment and environment. Frame of globalization and crisis.
Prisión preventiva y reforma de la justicia penal. Una exploración sociológica sobre el caso de la Provincia de Santa Fe, Argentina
Authors: Sozzo Máximo , Somaglia Maialén
Published: November 2017

En Argentina la centralidad de la prisión preventiva y su utilización extendida son rasgos fundamentales del funcionamiento de la justicia penal. En los últimos treinta años se han producido una serie de procesos de reforma de la justicia penal, a nivel latinoamericano, que han tratado de cambiar la dinámica de su funcionamiento. En la provincia de Santa Fe, particularmente, estos cambios se han materializado en la sanción de un nuevo Código Procesal Penal en el año 2007. En éste artículo mencionaremos una serie de interpretaciones posibles sobre las modificaciones en el uso de la prisión preventiva en el marco del nuevo proceso penal,  partiendo del análisis de una serie de datos estadísticos sobre la población privada de su libertad en establecimientos penitenciarios y policiales en el territorio de la provincia y del análisis de entrevistas semiestructuradas realizadas a los agentes de de la nueva justicia penal del centro y norte de la Provincia de Santa Fe.
Protección Penal: una lectura posible a las propuestas de baja de la edad de imputabilidad
Authors: Morales José E.
Published: November 2017

Frente a un “nuevo” debate sobre la Ley Penal Juvenil en nuestro país, es dado observar aquello que se repite:un acontecimiento “extraordinario” que presume la participación de un joven –no cualquier joven-, relevancia en la agenda mediática, repercusión en la opinión pública, interpelación al poder legislativo, la baja de la edad de imputabilidad como variable más significativa en las propuestas de reforma.

Partiendo de un recorrido por los proyectos de Ley Penal Juvenil que en el periodo 2012-2017 se han propuesto reemplazar el Régimen Penal de la Minoridad vigente en nuestro país, el presente artículo presenta una serie de elementos que permiten una lectura posible sobre la persistencia de la baja de la edad de imputabilidad en la gran mayoría de dichos proyectos: la dinámica de individuación que subyace de los modelos de política social en el diseño de programas dirigidos hacia niños, niñas y adolescentes y la conjunción del Estado de su faceta de restitución y protección de derechos con su rol de intervención penal. Para ello tomaremos como referencia el análisis de Silvia Guemureman sobre los modelos de política social en la Ciudad de Buenos Aires.
Brasil y la nueva generación de Acuerdos de Cooperación y Facilitación de Inversiones: un análisis del Tratado con México
Authors: Ghiotto Luciana , Arroyo Picard Alberto
Published: November 2017

El artículo estudia las cláusulas del Acuerdo de Cooperación y Facilitación de las Inversiones (ACFI) entre Brasil y México en 2015. Se compara con las cláusulas estándar de los Tratados Bilaterales de Inversión (TBI) firmados en los años noventa. Se observa en particular el cambio de situación de Brasil, que en esos años no ratificó sus TBI firmados, pero que actualmente firma Acuerdos para proteger las inversiones de sus empresas. Si bien el ACFI posee características novedosas, mantiene cláusulas similares a los TBI como el Trato Nacional y Trato de Nación Más Favorecida, y no incluye obligaciones vinculantes para los inversionistas y sus inversiones. Se pone especial énfasis analítico en el sistema de solución de controversias propuesto.
El accionar de los “fondos buitre”: una caracterización a partir del conflicto con la República Argentina
Authors: Val María Emilia
Published: November 2017

En los últimos años, los llamados "fondos buitre" se han constituido en uno de los principales temas de la agenda política, jurídica, económica y académica internacional.  El caso argentino ha mostrado las consecuencias del accionar especulativo de estos actores para los procesos de reestructuración de deuda soberana y revivido la discusión en torno a iniciativas de reforma en la arquitectura financiera internacional. En este escrito, describiremos la estrategia buitre, las condiciones históricas que permitieron la consolidación de la misma y la evolución de los litigios contra países soberanos para finalmente centrarnos en el desarrollo del recientemente concluido conflicto entre la República Argentina y sus acreedores holdouts.
El cambio de la Look East Policy a la Act East Policy en India
Authors: Baroni Paola Andrea , Dussort Maria Noel
Published: November 2017

La Look East Policy marcó la forma en que la India se ha vinculado con sus vecinos del Sudeste Asiático desde 1991. Inicialmente enfocada en los aspectos comerciales, su objeto se amplió hacia la construcción de vínculos económicos, institucionales y de seguridad y defensa. La administración de Narendra Modi rebautizó este acercamiento como Act East Policy, propiciando una acción mayor.

El objetivo del presente trabajo es analizar las principales acciones hacia el Sudeste Asiático en lo económico-comercial, institucional y de seguridad, así como los resultados obtenidos en la última década y los desafíos que se presentan a futuro.
Vấn đề phát triển liên kết vùng với phát triển bền vững vùng Tây Bắc
Authors: Phạm Quốc Thành
Published: November 2017

Phát triển kinh tế-xã hội vùng và tăng cường liên kết vùng là những vấn đề có mối quan hệ chặt chẽ với nhau và được hình thành, tồn tại một cách khách quan trong quá trình phát triển kinh tế - xã hội của nhiềuquốc gia trên thế giới, trong đó có Việt Nam.Có nhiều các tiếp cận khác nhau khi nghiên cứu vùng và liên kết vùng, nhưng nhìn chung, cơ sở lý luận về vùng, phát triển kinh tế vùng, liên kết phát triển vùng chủ yếu được căn cứ theo các lý thuyết về phân cực, phân vùng, tăng trưởng kinh tế, kinh tế không gian, quy hoạch phát triển,… Trong bối cảnh Việt Nam ngày càng mở rộng sự hội nhập với thế giới, nền kinh tế đất nước đứng trước nhiều thách thức mới, chính sách phát triển vùng, liên kết vùng có vai trò ngày càng quan trọng, không những là một nguồn động lực cho sự phát triển kinh tế, mà đồng thời cũng là một công cụ chính sách hữu hiệu cho các vùng khó khăn (trong đó có Tây Bắc) trong việc bảo tồn tài nguyên, sinh thái, ổn định an ninh, chính trị, xã hội,… Với bài viết này, bên cạnh việc luận giải các vấn đề lý thuyết liên quan đến vùng và liên kết vùng, tác giả đã chỉ ra những lợi thế (về địa lý, tài nguyên, điều kiện kinh tế-xã hội) cũng như những khó khăn, thách thức đối với việc phát triển vùng và liên kết vùng ở Tây Bắc. Đồng thời, tác giả cũng đề xuất được một số khuyến nghị có giá trị bao gồm những giải pháp căn cơ (khôi phục các thế mạnh tự nhiên, phát huy lợi thế so sánh,…) và những giải pháp trước mắt (giao rừng đến từng hộ dân, phát triển sản phẩm nông nghiệp ôn đới, quản lý tốt việc khai thác khoáng sản,…).
The Need for Longitudinal Studies on Co-occurring Alcohol Use and Anxiety Disorders among Older Adults
Authors:   Korean Journal of Research in Gerontology, Kim Seungyoun
Published: November 2017

Co-occurring alcohol use and anxiety disorders is common in older adults and contributes to poor health
outcomes, higher health care utilization, heightened mortality, and social dysfunction in later life. Although
there are several proposed theoretical explanations for the association between drinking and mental health
disorders (e.g., the precipitation model, the self-medication model, and the mutual maintenance model), few
studies have tested the longitudinal time-dependent relationship between alcohol use and anxiety disorders
in later life, in part, because longitudinal studies are limited. Better understanding of the temporal sequence
of the relationship between alcohol use and anxiety disorders will have implications for improving
prevention and treatment programs for at-risk drinking and anxiety in the older population.
Surface confinement induces the formation of solid-like insulating ionic liquid nanostructures
Authors: Galluzzi Massimiliano , Bovio Simone , Milani Paolo , Podestà Alessandro
Published: November 2017

We report on the modification of the electric properties of the imidazolium-based [BMIM][NTf2] ionic liquid upon surface confinement in the sub-monolayer regime. Solid-like insulating nanostructures of [BMIM][NTf2] spontaneously form on a variety of insulating substrates, at odd with the liquid and conductive nature of the same substances in the bulk phase. A systematic spatially resolved investigation by atomic force microscopy of the morphological, mechanical and electrical properties of [BMIM][NTf2] nanostructures showed that this liquid substance rearranges into lamellar nanostructures with a high degree of vertical order and enhanced resistance to mechanical compressive stresses and very intense electric fields, denoting a solid-like character. The morphological and structural reorganization has a profound impact on the electric properties of supported [BMIM][NTf2] islands, which behave like insulator layers with a relative dielectric constant between 3 and 5, comparable to those of conventional ionic solids, and significantly smaller than those measured in the bulk ionic liquid. These results suggest that in the solid-like ordered domains confined either at surfaces or inside the pores of the nanoporous electrodes of photo-electrochemical devices, the ionic mobility and the overall electrical properties can be significantly perturbed with respect to the bulk liquid phase, which would likely influence the

performance of the devices.
Tracer study of graduate students in guidance and counseling program at the faculty of education in Universitas Riau
Authors: Rosmawati Rosmawati , Donal Donal
Published: November 2017

Tracer study is one of the studies that need to be done regularly to find out the relevance level between academic programs organized by an educational institution (study program) with the needs on the field, in the end will be a reference to the study program to create competitive advantage through the opinion of the alumni. This research uses a quantitative descriptive method. The Sampling method used purposive sampling method. In this, research will be seen completed the alumni career that includes alumni who go on education, the reason for continuing education alumni, alumni cumulative achievement index, waiting time to work, alumni satisfaction, and suitability between the field of education and employment. Tracer study results produce a number of conclusions and implementation suggestions that are very useful for improving the learning.
Perceptions around teacher's social support with student achievement motivation
Authors: Oktasari Maria
Published: November 2017

Several indications that indicate student in low achievement motivation, among others: (1) lack of enthusiasm to follow the lesson, (2) less attention to the teacher, (3) the students have not targeted yet, (4) students tend to ignore the task, (5) (6) students are less harmonious with teachers, (7) students are lazy to learn, and (8) some students feel scared with the teacher. Students 'perceptions of teacher's social support are factors that allegedly influence students' achievement motivation. This study aims to determine the relationship of students' perceptions of the social support of teachers with achievement motivation. The method used throughout this research is quantitative with regression technique. Samples numbered to 206 students of SMA Negeri 1 V Koto Timur Padang Pariaman, and selected by proportional random sampling. The instrument used is the student's perception scale of teacher's social support and achievement motivation. The research findings indicate that there is a significant correlation between around teacher's social support with student achievement motivation.
Gaza: una espina en el corazón de la humanidad
Authors: Martínez Mora Nathalia , Useche Aldana Oscar
Published: November 2017

Sin resumen.
Buen vivir, decolonialidad y bioética. Discusiones, aportes y articulaciones
Authors: Salamanca López Leonardo
Published: November 2017

Está reflexión quiere mostrar cómo el proyecto de decolonialidad, la propuesta del Buen Vivir y la Bioética hacen aportes importantes a problemas actuales provenientes del proyecto de la Modernidad, como por ejemplo, las relaciones de poder, la pobreza, el deterioro ambiental, el consumo, el sentido de comunidad, la lucha por la supervivencia y otros de igual o mayor relevancia. Dichos problemas se pueden articular y proyectar de manera dialógica y complementaria desde las perspectivas y aportes de estos tres campos. El artículo está dividido en tres aparatados. En primer lugar, se presenta una descripción de algunas críticas al modelo modernidad/colonialidad. A continuación, se hace alusión al sentido y las posibilidades que ofrece el “Buen Vivir” o “Vivir Bien”. Por último, se establecen algunos puntos de encuentro entre las perspectivas del proyecto decolonial, el “Buen Vivir” y la Bioética.
La enseñanza de la historia reciente y transición política en Colombia: constantes, fracturas y nuevos horizontes
Authors: Dominguez Acevedo Jhon Diego
Published: November 2017

En este artículo defendemos la hipótesis de que la paz no tendrá sentido sin un cambio importante en el orden educativo. Por ello, exploramos las problemáticas de la enseñanza de la historia del tiempo reciente en contextos educativos y sus procesos de transición en dos apartados: Primero, analizamos las discusiones conceptuales sobre la historia del tiempo presente y reciente (génesis y transformación). En el segundo, presentamos los fines y mecanismos que han contribuido a la consolidación de la enseñanza de la historia reciente en Colombia.
"Cultura ciudadana” en Bogotá: biopolítica, hegemonización y pánico cultural en la época del culturalismo
Authors: Restrepo Eduardo
Published: November 2017

Este artículo examina cómo se ha naturalizado una idealización y romantización de la noción de “cultura ciudadana”. Con ello se pretende mostrar que, contrario a esas percepciones idílicas, lo que está en juego con esta noción-estrategia es una modalidad de biopolítica que produce un “pánico cultural” para producir un particular sujeto —un ciudadano adecuado— desde retóricas salvacionistas, las cuales que despliegan un autoritarismo moral eurocentrado y clasista. El logro más destacado de la “cultura ciudadana” no es lo que los expertos y burócratas celebran desde estadísticas de “seguridad” y “bienestar”, sino su hegemonización, que oblitera el entender las problemáticas de una ciudad desde perspectivas diferentes a su reduccionismo culturalista.
Deleuze y Merleau-ponty. La carne del mundo
Authors: Montenegro Vargas Gonzalo
Published: November 2017

A pesar de la distancia que parecen evidenciar la filosofía de Merleau-Ponty y de Deleuze, es posible descubrir más que complicidades analógicas respecto de la crítica que dirigen a Husserl. En el terreno estético, por ejemplo, podemos constatar que las últimas reflexiones de Merleau-Ponty, presentes fundamentalmente en Lo visible y lo invisible, representan un parangón constante para el desarrollo de obras como la que Deleuze consagra al pintor Francis Bacon. Por lo tanto, la investigación que sigue se aboca a definir los lugares y motivos principales en los que, de la mano de la lectura que efectúan de Husserl, se reconocen entre Merleau-Ponty y Deleuze puntos de contacto que desafían la indiferencia aparente desde la que se comprenden sus respectivas filosofías.
Filosofía y filosofar en la educación. El reto de la enseñanza de la filosofía: filosofar
Authors: Rey Vásquez Elías Manaced
Published: November 2017

Se pretende reflexionar sobre el ejercicio académico de la enseñanza de la filosofía y el papel que el docente tiene en ella. El docente debe posibilitar filosofar, que se asocia comúnmente con el simple ejercicio de hacer preguntas. De ahí la necesidad de considerar al docente de filosofía como aquel que comprende que su enseñanza es un problema que necesita ser tomado en serio, puesto que implica a todo el ser del Hombre. Se necesita de un docentefilósofo que viva con sus estudiantes el uso libre y voluntario de la razón, posibilitado por el asombro, por la pasión hacia la vida, para superar los niveles eminentemente retóricos de hacer la pregunta por la pregunta, y así llegar a niveles vitales del estudiante con necesidad real de filosofar. Autores clásicos y actuales guiarán esta reflexión.
Algunas razones filosóficas contra el maltrato animal ¿por qué los animales humanos deberíamos considerar moralmente a los animales no humanos?
Authors: Rincón Higuera Eduardo
Published: November 2017

La creciente preocupación por la crueldad en el trato hacia los animales ha sido impulsada, en gran medida, por la difusión en ámbitos académicos de enfoques filosóficos que abordan dicha cuestión desde posturas y principios distintos. En el marco de este escrito esbozaré, a modo de prolegómeno, algunas de esas razones filosóficas que argumentan la incorrección moral del maltrato animal. Según dicho propósito, reconstruiré los principales conceptos que dieron inicio a la discusión sobre la necesidad de ampliar el marco de la comunidad moral para la consideración de los animales. En esa labor, abordaré la conceptualización de derecho de los animales hecha por Henry Salt y la formulación del principio de igual consideración de intereses de Singer, así como, el enfoque de las capacidades de Martha Nussbaum. Dichas consideraciones construirán la formulación inicial de un marco que explica por qué deberíamos considerar moralmente a los animales no humanos.