bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictions of novel Schistosoma mansoni - human protein interactions consistent with experimental data
Authors: White Bear J. , Long Thavy , Skinner Danielle , McKerrow James H.
Published: August 2018

Infection by the human blood fluke, Schistosoma mansoni involves a variety of cross-species protein- protein interactions. The pathogen expresses a diverse arsenal of proteins that facilitate the breach of physical and biochemical barriers present in skin evasion of the immune system, and digestion of human plasma proteins including albumin and hemoglobin, allowing schistosomes to reside in the host for years. However, only a small number of specific interactions between S. mansoni and human proteins have been identified. We present and apply a protocol that generates testable predictions of S. mansoni-human protein interactions. In this study, we have preliminary predictions of novel interactions between schistosome and human proteins relevant to infection and the ability of the parasite to evade the immune system. We applied a computational whole-genome comparative approach to predict potential S. mansoni-human protein interactions based on similarity to known protein complexes. We first predict S. mansoni -human protein interactions based on similarity to known protein complexes. Putative interactions were then scored and assessed using several contextual filters, including the use of annotation automatically derived from literature using a simple natural language processing methodology. Next, in vitro experiments were carried out between schistosome and host proteins to validate several prospective predictions. Our method predicted 7 out of the 10 previously known cross-species interactions involved in pathogenesis between S. mansoni and its human host. Interestingly, two novel putative interactions involving Schistosoma proteins, the cercarial elastase SmCE, and the adult tegument surface protein Sm29, were also predicted and experimentally characterized. Preliminary data suggest that elafin, a host endogenous serine protease inhibitor, may be a novel substrate for SmCE. Additionally, CD59, an inhibitor of the membrane attack complex, could interact with Sm29. Furthermore, the application framework provides an integrated methodology for investigation of host-pathogen interactions and an extensive source of orthogonal data for experimental analysis. We have made the predictions available for community perusal.
Exploring Exemplary Optoelectronic and Charge Transport Properties of KCuX(X=Se,Te)
Authors: Parveen Atahar , Vaitheeswaran G.
Published: August 2018

We report the electronic structure, optical and charge transport properties of the unexplored ternary Zintl phases KCuX(X=Se,Te) from the first principles calculations employing the full-potential linearized augmented plane-wave (FLAPW) method with the Tran Blaha modified Becke-Johnson (TBmBJ) potential. It is demonstrated that the materials are direct band gap (1.13, 1.38 eV) semiconductors with covalent bonding between Cu and (Se/Te). The calculated low effective mass and high carrier mobility (over 105 cm2/V.s) accentuate that KCuX have good carrier transport and the materials may have possible applications in solar cell absorbers and nanoelectronic devices. Absorption spectra indicates that the ternary crystals are UV-A light absorbers and could be useful in photovoltaic and photodetector applications. A study on the effect of pressure (till 5 GPa) is carried out in order to further explore the materials for their electronic band gaps and charge transport properties as they are proposed to be useful in future contemporary electronic devices. It is observed that pressure enhances the intrinsic carrier mobility and thermal stability of KCuX, indicating that the materials can withstand robust external conditions.
Application of a dye-based mitochondrion-thermometry to determine the receptor downstream of prostaglandin E2 involved in the regulation of hepatocyte metabolism
Authors: Shen Lei , Xie Tao-Rong , Yang Run-Zhou , Chen Yan , Kang Jian-Sheng
Published: August 2018

Temperature distributions inside a living cell reflect the thermodynamics and functions of cellular components. We used a newly-developed method of mitochondrial thermometry based on Rhodamine B methyl ester, which equilibrates as a thermosensitive mixture of nonfluorescent and fluorescent resonance forms. Prostaglandin E2 (PGE2) is released from hepatic non-parenchymal Kupffer cells and acts as an inflammatory factor to impact various functions of hepatocytes. The activity of PGE2 on energy mechanism of hepatocytes has not been fully elucidated and in particular, which PGE2 receptor mediates the functions has been elusive. We identified EP4 as the major receptor of PGE2 via our mitochondrion-thermometry approach and then substantiated this receptor’s role in hepatic metabolism. We discovered that PGE2 is able to decrease intracellular temperature of hepatocytes, via increasing some lipogenic genes’ expressions, hampering lipolysis and mitochondrial β-oxidation, reducing intracellular ATP level and elevating cAMP level through EP4 receptor. The redox status of hepatocytes represented by FAD vs FAD + NADH ratio is influenced by PGE2 in an EP4 receptor-dependent manner. Collectively, these data demonstrate that PGE2 regulates metabolism of hepatocytes mainly through EP4 receptor.
DR region of Na+-K+-ATPase is a new target to protect heart against oxidative injury
Authors: Hua Fei , Wu Zhiyuan , Yan Xiaofei , Zheng Jin , Sun Haijian , Cao Xu , Bian Jin-Song
Published: August 2018

Previous studies have shown that the activity and expression of Na+/K+-ATPase (NKA) are down-regulated in the failing hearts, and that an antibody against the DR-region of NKA (DR-Ab) can stimulate its activity. The present study was designed to investigate the beneficial effects of this antibody against cardiac injury and the underlying mechanisms. We found that DR-Ab improved cardiac function, alleviated cardiac hypertrophy and reduced oxidative stress in isoproterenol-treated mice. In AC16 human cardiomyocytes, DR-Ab increased cell viability and attenuated apoptosis under oxidative stress. Corresponding to the observation of reduced NKA activity, NKA abundance on plasma membrane was lowered during oxidative stress. Suppressed activity of protein phosphatase 2 A (PP2A) was responsible for the loss of membrane NKA due to the increased phosphorylation of key serine residues that trigger endocytosis. Incubation with DR-Ab restored PP2A activity and stabilized NKA expression on the plasma membrane. Inhibitors of PP2A abolished the protective effect of DR-Ab against oxidative stress. In summary, our data indicate that loss of membrane NKA may contribute to cardiac pathologies in heart failure. DR-Ab, by stabilizing membrane NKA, protects cardiomyocytes against oxidative injury and improves cardiac function in the failing hearts, suggesting a novel approach to treat heart failure.
Mapping the Potential Global Codling Moth (Cydia pomonella L.) Distribution Based on a Machine Learning Method
Authors: Jiang Dong , Chen Shuai , Hao Mengmeng , Fu Jingying , Ding Fangyu
Published: August 2018

The spread of invasive species may pose great threats to the economy and ecology of a region. The codling moth (Cydia pomonella L.) is one of the 100 worst invasive alien species in the world and is the most destructive apple pest. The economic losses caused by codling moths are immeasurable. It is essential to understand the potential distribution of codling moths to reduce the risks of codling moth establishment. In this study, we adopted the Maxent (Maximum Entropy Model), a machine learning method to predict the potential global distribution of codling moths with global accessibility data, apple yield data, elevation data and 19 bioclimatic variables, considering the ecological characteristics and the spread channels that cover the processes from growth and survival to the dispersion of the codling moth. The results show that the areas that are suitable for codling moth are mainly distributed in Europe, Asia and North America, and these results strongly conformed with the currently known occurrence regions. In addition, global accessibility, mean temperature of the coldest quarter, precipitation of the driest month, annual mean temperature and apple yield were the most important environmental predictors associated with the global distribution of codling moths.
Genetic polymorphisms of ALDH2 are associated with lumbar disc herniation in a Chinese Han population
Authors: Dong Qi , Ren Guoxia , Zhang Kuaiqiang , Liu Deyu , Dou Qunli , Hao Dingjun
Published: August 2018

Aldehyde dehydrogenase (ALDH) is a key enzyme for the catalytic oxidation of acetaldehyde to acetic acid. Genetic polymorphisms of ALDH2 have been associated with a wide range of diseases and cancers. However, little information is found about the association between ALDH2 polymorphisms and lumbar disc herniation (LDH) in Chinese Han population. We investigated the association between single nucleotide polymorphisms (SNPs) in ALDH2 and LDH risk in a case–control study that included 380 LDH cases and 692 healthy controls. Eight SNPs were selected and genotyped using the Sequenom MassARRAY platform. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression after adjusting for gender and age. In the allele model analysis, we found the frequency of the “A” allele of rs671 was significantly higher in LDH cases than in controls (OR = 1.414, 95%CI: 1.109–1.803, P = 0.005). In the genetic model analysis, we found the minor allele “A” of rs671 was associated with increased risk of LDH under log-additive model (OR = 1.42, 95%CI: 1.11–1.82, P = 0.0062); and the minor allele “C” of rs7296651 was associated with decreased risk of LDH under over-dominant model (OR = 0.72, 95%CI: 0.53–0.97, P = 0.031). Additionally, the haplotype “GGCTCACG” constructed by rs886205, rs2238152, rs4648328, rs441, rs4646778, rs671, rs11066028, and rs7296651 was associated with increased risk of LDH (OR = 1.45; 95% CI = 1.11–1.90; P = 0.0071). Our data shed new light on the association between genetic polymorphisms of ALDH2 and LDH susceptibility in a Chinese Han population.
A Versatile Sample Processing Workflow for Metagenomic Pathogen Detection
Authors: Wylezich Claudia , Papa Anna , Beer Martin , Höper Dirk
Published: August 2018

Metagenomics is currently the only generic method for pathogen detection. Starting from RNA allows the assessment of the whole sample community including RNA viruses. Here we present our modular concerted protocol for sample processing for diagnostic metagenomics analysis of human, animal, and food samples. The workflow does not rely on dedicated amplification steps at any stage in the process and, in contrast to published methods, libraries prepared accordingly will yield only minute amounts of unclassifiable reads. We confirmed the performance of the approach using a spectrum of pathogen/matrix-combinations showing it has the potential to become a commonly usable analytical framework.
Sex-specific effects of food supplementation on hibernation performance and reproductive timing in free-ranging common hamsters
Authors: Siutz Carina , Valent Margit , Ammann Viktoria , Niebauer Ariane , Millesi Eva
Published: August 2018

Hibernation is characterized by reduced metabolism and body temperature during torpor bouts. Energy reserves available during winter play an important role for hibernation and some species respond to high energy reserves with reduced torpor expression. Common hamsters are food-storing hibernators and females hibernate for shorter periods than males, probably related to larger food stores. In this study, we provided free-ranging common hamsters with sunflower seeds shortly before winter and recorded body temperature using subcutaneously implanted data loggers. We compared hibernation patterns and body mass changes between individuals with and without food supplements and analysed reproductive onset in females. Supplemented males delayed hibernation onset, hibernated for much shorter periods, and emerged in spring with higher body mass than unsupplemented ones. Additional food did not affect hibernation performance in females, but supplemented females emerged earlier and preceded those without food supplements in reproductive onset. Thus, males and females differently responded to food supplementation: access to energy-rich food stores enabled males to shorten the hibernation period and emerge in better body condition, probably enhancing mating opportunities and reproductive success. Females did not alter hibernation patterns, but started to reproduce earlier than unsupplemented individuals, enabling reproductive benefits by an extended breeding period.
Enhancement of ethanol production in very high gravity fermentation by reducing fermentation-induced oxidative stress in Saccharomyces cerevisiae
Authors: Burphan Thanawat , Tatip Supinda , Limcharoensuk Tossapol , Kangboonruang Kitsada , Boonchird Chuenchit , Auesukaree Choowong
Published: August 2018

During fermentation, yeast cells encounter a number of stresses, including hyperosmolarity, high ethanol concentration, and high temperature. Previous deletome analysis in the yeast Saccharomyces cerevisiae has revealed that SOD1 gene encoding cytosolic Cu/Zn-superoxide dismutase (SOD), a major antioxidant enzyme, was required for tolerances to not only oxidative stress but also other stresses present during fermentation such as osmotic, ethanol, and heat stresses. It is therefore possible that these fermentation-associated stresses may also induce endogenous oxidative stress. In this study, we show that osmotic, ethanol, and heat stresses promoted generation of intracellular reactive oxygen species (ROS) such as superoxide anion in the cytosol through a mitochondria-independent mechanism. Consistent with this finding, cytosolic Cu/Zn-SOD, but not mitochondrial Mn-SOD, was required for protection against oxidative stress induced by these fermentation-associated stresses. Furthermore, supplementation of ROS scavengers such as N-acetyl-L-cysteine (NAC) alleviated oxidative stress induced during very high gravity (VHG) fermentation and enhanced fermentation performance at both normal and high temperatures. In addition, NAC also plays an important role in maintaining the Cu/Zn-SOD activity during VHG fermentation. These findings suggest the potential role of ROS scavengers for application in industrial-scale VHG ethanol fermentation.
Class I and II Histone Deacetylase Inhibitors Differentially Regulate Thermogenic Gene Expression in Brown Adipocytes
Authors: Rajan Anubama , Shi Hang , Xue Bingzhong
Published: August 2018

Class I histone deacetylase inhibitors (HDACis) enhance whole body energy expenditure and attenuate high fat diet-induced insulin resistance. However, it is not clear whether this is exerted directly through activating brown fat thermogenesis. Here, we find that pan-HDACi TSA exerts paradoxical effects on brown fat gene expression, as it inhibits the expression of Ucp1, Pparγ and Prdm16 in brown adipocytes, while promoting the expression of other brown fat-specific genes such as Pgc1α, Pgc1β, Acox1 and Cidea. Further studies indicate that class I HDACi MS-275 significantly increases; whereas class II HDACi MC-1568 markedly reduces, the expression of Ucp1 and other brown fat-specific genes in treated brown adipocytes. ChIP assay reveals an enhanced H3 acetylation at the Pgc1α promoter in MS-275-treated brown adipocytes; whereas the effect of MC-1568 is associated with up-regulation of retinoblastoma protein (Rb) and an enhanced acetylation of H3K27 at the Rb promoter. Loss of function studies indicate that Pgc1α up-regulation largely mediates the stimulatory effect of class I HDACis on the thermogenic program, whereas up-regulation of Rb may be responsible for the inhibitory effect of class II HDACis. Thus, our data suggest that class I and II HDACis have differential effects on brown fat thermogenic gene expression.
Aptamer-based colorimetric determination of Pb2+ using a paper-based microfluidic platform
Authors: Fakhri Neda , Hosseini Morteza , Tavakoli Omid
Published: August 2018

In this research, a novel paper-based microfluidic aptasensor was designed in order to detect different concentrations of lead in water.
Enhanced photocatalytic H2 production of cadmium-free rGO-mediated ZnS/CuS heterojunction derived from a MOF
Authors: Xu Mei-Ling , Cui Jian-Dong , Zhao Jia-Hui , Liu Fu-Tian , Li Kui
Published: August 2018

The MOF-templated porous ZnS/CuS heterojunction with rGO as the charge carrier mediator exhibits enhanced photocatalytic hydrogen production under visible light illumination.
Hybrid nanoparticles for magnetic and plasmonic hyperthermia
Authors: Ovejero Jesus G. , Morales Irene , de la Presa Patricia , Mille Nicolas , Carrey Julian , Garcia Miguel A. , Hernando Antonio , Herrasti Pilar
Published: August 2018

The present manuscript reports the use of hybrid magneto-plasmonic nanoparticles (HMPNPs) based on iron oxide nanoparticles and Au nanorods as colloidal nanoheaters.
Enhancing the blinking fluorescence of single-molecule localization imaging by using a surface-plasmon-polariton-enhanced substrate
Authors: Chien Fan-Ching , Lin Chun-Yu , Abrigo Gerald
Published: August 2018

Single-molecule localization microscopy combined with the surface plasmon polariton-enhanced fluorescence of spontaneously blinking fluorophores was used to reduce the phototoxicity of biospecimens for single-molecule localization imaging.
Probing the structural and electronic properties of zirconium doped boron clusters: Zr distorted B12 ligand framework
Authors: Sun Weiguo , Xia Xinxin , Lu Cheng , Kuang Xiaoyu , Hermann Andreas
Published: August 2018

The lowest-energy structure ZrB12 shows that the dopant Zr atom breaks the triangle B3 present in other M@B12 clusters (M = Co, Rh, Ir) to form a quasi-linear B3 unit in the B12 motif and induce strong Zr–B interactions that enhance the stability of the neutral half-sandwich ZrB12 cluster.
The electronic structure and stability of germanium tubes Ge30H12and Ge33H12
Authors: Duong Long Van , Matito Eduard , Solà Miquel , Behzadi Hadi , Momeni Mohammad Jafar , Nguyen Minh Tho
Published: August 2018

To explore the possibility of large cylindrical Ge clusters, we investigated the molecular and electronic structure of the germanium tube Ge30H12, composed of six parallel, planar hexagons using DFT calculations, and Ge33H12generated from the insertion of Ge atoms at the center of three inner hexagons of Ge30H12.
Enhanced electrochemical performance of Li-rich cathode materials through microstructural control
Authors: Serrano-Sevillano Jon , Reynaud Marine , Saracibar Amaia , Altantzis Thomas , Bals Sara , van Tendeloo Gustaaf , Casas-Cabanas Montse
Published: August 2018

Structural defects are used as a design opportunity to prepare better battery materials: limiting capacity and voltage fadings in Li2MnO3.
Correction: Changing relations between proteins and osmolytes: a choice of nature
Authors: Rani Anjeeta , Venkatesu Pannuru
Published: August 2018

Correction for ‘Changing relations between proteins and osmolytes: a choice of nature’ by Anjeeta Rani et al., Phys. Chem. Chem. Phys., 2018, 20, 20315–20333.
Engineering surface defects and metal–support interactions on Pt/TiO2(B) nanobelts to boost the catalytic oxidation of CO
Authors: Liu Jinghua , Ding Tong , Zhang Hao , Li Guangcheng , Cai Jinmeng , Zhao Dongyue , Tian Ye , Xian Hui , Bai Xueqin , Li Xingang
Published: August 2018

The thermally reduced Pt/TiO2(B) catalysts show high catalytic activity and good water resistance for the catalytic oxidation of CO.
Weakly interacting solvation spheres surrounding a calixarene-protected tetrairidium carbonyl cluster: contrasting effects on reactivity of alkane solvent and silica support
Authors: Palermo Andrew P. , Zhang Shengjie , Hwang Son-Jong , Dixon David A. , Gates Bruce C. , Katz Alexander
Published: August 2018

A substituted tetrairidium carbonyl cluster on a silica support undergoes hydrogen activation at a rate and with a mechanism different from the cluster in solution.
The bismuth oxyhalide family: thin film synthesis and periodic properties
Authors: Gómez-Velázquez Laura S. , Hernández-Gordillo Agileo , Robinson Matthew J. , Leppert Valerie J. , Rodil Sandra E. , Bizarro Monserrat
Published: August 2018

The complete bismuth oxyhalides were synthesized as thin films. β-Bi2O3 films were transformed into BiOX for X = F, Cl and Br by chemical baths; BiOI was obtained by spraying the solution directly. All BiOX films present photocatalytic activity under simulated sunlight.
Supercapacitor with high cycling stability through electrochemical deposition of metal–organic frameworks/polypyrrole positive electrode
Authors: Liu Yaozhi , Xu Na , Chen Weichao , Wang Xinlong , Sun Chunyi , Su Zhongmin
Published: August 2018

Through electrochemical deposition, a novel positive electrode comprising ZIF-67 and polypyrrole, showing ultrahigh cycling stability (100.7%, 40 000 cycles), was fabricated.
Heterometallic lanthanide-centred [NiII6LnIII] rings
Authors: Canaj Angelos B. , Tzimopoulos Demetrios I. , Kalofolias Dimitris A. , Siczek Milosz , Lis Tadeusz , Murrie Mark , Milios Constantinos J.
Published: August 2018

The syntheses, structures and magnetic properties of three new hetero-heptametallic [Ni6Ln] complexes are reported.
A photochromic zinc-based coordination polymer for a Li-ion battery anode with high capacity and stable cycling stability
Authors: Xia Shu-Biao , Li Fu-Shao , Shen Xiang , Li Xue , Cheng Fei-Xiang , Sun Cheng-Ke , Guo Hong , Liu Jian-Jun
Published: August 2018

A zinc-based coordination polymer with photochromic 4,4′-bipyridinium derivatives as redox active building units is demonstrated as an anode material for Li-ion batteries.
Halloysite nanotube@carbon with rich carboxyl groups as a multifunctional adsorbent for the efficient removal of cationic Pb(ii), anionic Cr(vi) and methylene blue (MB)
Authors: Wang Penglei , Tang Yuanyuan , Liu Yunsong , Wang Tao , Wu Pengfei , Lu Xiao-Ying
Published: August 2018

A multifunctional halloysite@carbon with rich carboxyl group (HNT@CRC) is prepared using a facile and green method, and the adsorbent exhibits excellent adsorption performance towards pollutants with different features like Pb(ii), Cr(vi) and methylene blue (MB).
Effects of an ethanol extract fromLactobacillus paracaseisubsp.paracaseiNTU 101 fermented skimmed milk on lipopolysaccharide-induced periodontal inflammation in rats
Authors: Liu Te-Hua , Tsai Tsung-Yu , Pan Tzu-Ming
Published: August 2018

NTU 101-fermented skimmed milk ethanol extract (NTU101FMEE) decreased pro-inflammatory cytokine levels and oxidative stress in the gingival tissues and serum of periodontal disease rat. NTU101FMEE inhibited alveolar bone loss induced by periodontal disease.
Evaluating polymer-supported isothiourea catalysis in industrially-preferable solvents for the acylative kinetic resolution of secondary and tertiary heterocyclic alcohols in batch and flow
Authors: Guha Nitul Ranjan , Neyyappadath Rifahath M. , Greenhalgh Mark D. , Chisholm Ross , Smith Samuel M. , McEvoy Megan L. , Young Claire M. , Rodríguez-Escrich Carles , Pericàs Miquel A. , Hähner Georg , Smith Andrew D.
Published: August 2018

Highly recyclable isothiourea catalysts on various polymer supports are reported for the kinetic resolution of alcohols.
Effect of exercise on the plasma vesicular proteome: a methodological study comparing acoustic trapping and centrifugation
Authors: Bryl-Górecka Paulina , Sathanoori Ramasri , Al-Mashat Mariam , Olde Björn , Jögi Jonas , Evander Mikael , Laurell Thomas , Erlinge David
Published: August 2018

Improved reproducibility in seed particle mediated acoustic trapping of submicron particles enables clinical biomarker studies in extracellular vesicles.
Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents
Authors: Maguire Casey J. , Chen Zhi , Mocharla Vani P. , Sriram Madhavi , Strecker Tracy E. , Hamel Ernest , Zhou Heling , Lopez Ramona , Wang Yifan , Mason Ralph P. , Chaplin David J. , Trawick Mary Lynn , Pinney Kevin G.
Published: August 2018

Dihydronaphthalene analogues as potent inhibitors of tubulin polymerization, cytotoxic agents, and vascular disrupting agents (VDAs).
Novel glass fabric-reinforced polybenzoxazine–silicate composites with polyvinyl butyral for high service temperature applications
Authors: Kumar S. Rajesh , Mohan S. Krishna , Dhanasekaran J.
Published: August 2018

The aim of this study is to develop novel glass fabric-reinforced polybenzoxazine–silicate composites with enhanced performances, which can overcome the disadvantages related to the low crosslink density of glass fabric-reinforced polybenzoxazine composites.
Tungsten doped hydroxyapatite processed at different temperatures: dielectric behaviour and anti-microbial properties
Authors: Maiti Moumita , Sarkar Manas , Liu Donghong , Xu Shilang , Maiti Soumen , Paul Biplab Kumar , Das Sukhen
Published: August 2018

Electrical and antibacterial activities of bio-compatible W/HAp synthesizedviachemical precipitation followed by annealing at different temperature.
High-energy flexible quasi-solid-state lithium-ion capacitors enabled by a freestanding rGO-encapsulated Fe3O4 nanocube anode and a holey rGO film cathode
Authors: Liang Tian , Wang Huanwen , Xu Dongming , Liao Ke , Wang Rui , He Beibei , Gong Yansheng , Yan Chunjie
Published: August 2018

A high-energy flexible quasi-solid-state lithium-ion capacitor is constructed from a freestanding rGO-encapsulated Fe3O4 nanocube anode and holey rGO film cathode.
Self-assembly of folic acid dextran conjugates for cancer chemotherapy
Authors: Tang Yuxiang , Li Yihui , Xu Rong , Li Si , Hu Hang , Xiao Chen , Wu Honglian , Zhu Lin , Ming Jiaxiong , Chu Zhiqin , Xu Huibi , Yang Xiangliang , Li Zifu
Published: August 2018

Three-fold functionality of folic acid (FA) has been demonstrated in DOX@DEX-FA nanoparticles for cancer-targeted nanotherapeutics.
Hedgehog-inspired nanostructures for hydrogel-based all-solid-state hybrid supercapacitors with excellent flexibility and electrochemical performance
Authors: Sun Pengxiao , He Weidong , Yang Hongcen , Cao Ruya , Yin Jiangmei , Wang Chenggang , Xu Xijin
Published: August 2018

High-security deformable energy-storage devices that are mechanically robust, with considerable energy and power densities are becoming desirable for smart wearable electronics.
Natural products as modulators of the cyclic-AMP pathway: evaluation and synthesis of lead compounds
Authors: Sengupta Saumitra , Mehta Goverdhan
Published: August 2018

Natural product modulators of the cAMP pathway have been evaluated and their total synthesis campaign is described in detail.
Synthesis of polycyclic spirooxindoles via an asymmetric catalytic one-pot stepwise Aldol/chloroetherification/aromatization procedure
Authors: Jiang Yan , Yu Shuo-Wen , Yang Yi , Liu Ying-Le , Xu Xiao-Ying , Zhang Xiao-Mei , Yuan Wei-Cheng
Published: August 2018

A general method for the synthesis of chiral pentacyclic spirooxindoles containing a tetrahydropyrano[2,3-b]indole scaffold through a one-pot stepwise sequence is reported.
Tuning thermoresponsive network materials through macromolecular architecture and dynamic thiol-Michael chemistry
Authors: Chakma Progyateg , Digby Zachary A. , Via Jeremy , Shulman Max P. , Sparks Jessica L. , Konkolewicz Dominik
Published: August 2018

Synthesis of precision polymers crosslinked with dynamic thiol-Michael adducts is developed, and the materials are characterized to determine structure–property relationships.
Copper ligand and anion effects: controlling the kinetics of the photoinitiated copper(i) catalyzed azide—alkyne cycloaddition polymerization
Authors: El-Zaatari Bassil M. , Cole Shea M. , Bischoff Derek J. , Kloxin Christopher J.
Published: August 2018

The kinetic performance of amine-based ligands and counter anions on the copper(ii) catalyst in photoinduced-CuAAC reactions is explored.
Palladium-catalyzed denitrogenative cycloadditions and alkenylations of benzotriazoles with alkynes
Authors: Wang Yuanhao , Wang Zhiguo , Chen Xuewei , Tang Yefeng
Published: August 2018

Palladium-catalyzed denitrogenative cycloadditions and alkenylations of benzotriazoles with alkynes have been achieved under different conditions, which enable the divergent syntheses of three types of valuable scaffolds.
Theoretical modeling of charge transport in triphenylamine–benzimidazole based organic solids for their application as host-materials in phosphorescent OLEDs
Authors: Navamani K. , Samanta P. K. , Pati S. K.
Published: August 2018

Dynamic disorder and electric field affect the charge (hole and electron) transport in host-materials for OLEDs.
Expeditious isomerization of glucose to fructose in aqueous media over sodium titanate nanotubes
Authors: Kumar Sandeep , Nepak Devadutta , Kansal Sushil Kumar , Elumalai Sasikumar
Published: August 2018

Isomerization reaction of glucose to fructose over sodium titanate nanotubes (Na-TNTs) as a Lewis base catalyst was studied.
Rh(iii)-catalyzed synthesis of tetracyclic isoquinolinium salts via C–H activation and [4+2] annulation of 1-phenyl-3,4-dihydroisoquinolines and alkynes in ethanol
Authors: Dang Xinxin , He Yu , Liu Yingtian , Chen Xuehong , Li Jun-Long , Zhou Xian-Li , Jiang Hezhong , Li Jiahong
Published: August 2018

An efficient method to construct tetracyclic isoquinolinium salts via C–H activation and [4 + 2] annulation reactions in ethanol is described.
Eco-friendly synthesis of ionic helical polymers and their chemical properties and reactivity
Authors: Yamaguchi Isao , Tanaka Yuki , Wang Aohan
Published: August 2018

Reactions of salt((CN)2N−) with (R)-(−)- or (S)-(+)-2-methylpiperazine under eco-friendly conditions resulted in a yield of ionic helical polymers.
Recent advances in syntheses, properties and applications of TiO2nanostructures
Authors: Ali Imran , Suhail Mohd , Alothman Zied A. , Alwarthan Abdulrahman
Published: August 2018

TiO2is a compound of great importance due to its remarkable catalytic and distinctive semiconducting properties.
Highly reactive 2-deoxy-2-iodo-d-allo and d-gulo pyranosyl sulfoxide donors ensure β-stereoselective glycosylations with steroidal aglycones
Authors: Mestre Jordi , Collado David , Benito-Alifonso David , Rodríguez Miguel A. , Matheu M. Isabel , Díaz Yolanda , Castillón Sergio , Boutureira Omar
Published: August 2018

Highly stereoselective synthesis of challenging steroidal 2-deoxy-β-glycosides with d-xylo and d-ribo configurations enabled by low temperature activation of 2-deoxy-2-iodoglycopyranosyl sulfoxides.
Multinuclear iron–phenyl species in reactions of simple iron salts with PhMgBr: identification of Fe4(μ-Ph)6(THF)4 as a key reactive species for cross-coupling catalysis
Authors: Carpenter Stephanie H. , Baker Tessa M. , Muñoz Salvador B. , Brennessel William W. , Neidig Michael L.
Published: August 2018

The first direct syntheses, structural characterizations, and reactivity studies of multinuclear iron–phenyl species formed upon reaction of Fe(acac)3 and PhMgBr in THF are described.
Cs0.15FA0.85PbI3 perovskite solar cells for concentrator photovoltaic applications
Authors: Troughton Joel , Gasparini Nicola , Baran Derya
Published: August 2018

Recently developed, highly stable perovskite materials show promise for use in concentrator photovoltaics where the illumination intensity far exceeds standard test conditions.
A 3D printed wound cooling system incorporated with injectable, adsorbable, swellable and broad spectrum antibacterial scaffolds for rapid hematischesis processing
Authors: Ai Fanrong , Liu Tingwu , Liu Yu , Yang Kang , Liu Yishen , Wang Wenyan , Yuan Fushan , Dong Lina , Xin Hongbo , Wang Xiaolei
Published: August 2018

Uncontrolled hemorrhage remains a leading cause of early death after trauma, and contamination further challenges the wounded.
A traditional Chinese medicine therapy for coronary heart disease after percutaneous coronary intervention: a meta-analysis of randomized, double-blind, placebo-controlled trials
Authors: Chen Ruixue , Xiao Ya , Chen Minghao , He Jingyi , Huang Mengtian , Hong Xitao , Liu Xin , Fu Taoran , Zhang Jingzhi , Chen Liguo
Published: August 2018

Huoxue Huayu therapy (HXHY) has been widely used to treat cardiovascular diseases in traditional Chinese medicine (TCM) such as hypertension and coronary heart disease (CHD). The present study describes a meta-analysis of a series of prospective randomized, double-blind, placebo-controlled trials conducted to evaluate the effect of HXHY on patients with CHD after percutaneous coronary intervention (PCI). The Cochrane Library, PubMed, EMBASE, the China National Knowledge Infrastructure (CNKI), the Chinese Biomedical Literature database, and the Wanfang database were searched up until June 2018. A series of randomized controlled clinical trials were included and the subjects were patients with CHD who had undergone PCI. The experimental group was treated with HXHY therapy, and the control group was treated with placebo; meanwhile, all the patients accepted conventional Western medicine. Review Manager 5.3 software was used for the statistical analysis. Ten trials were included in the final study. The overall risk of bias assessment was low. HXHY had a greater beneficial effect on reducing the in-stent restenosis (ISR) rate (RR = 0.57, 95% confidence interval [CI] [0.40–0.80], P=0.001) and the degree of restenosis (MD = −8.89, 95% CI [−10.62 to −7.17], P<0.00001) compared with Placebo. Moreover, HXHY was determined to be more effective in improving Seattle Angina Questionnaires (SAQ) and the revascularization rate (RR = 0.54, 95% CI [0.32–0.90], P=0.02) compared with Placebo, whereas the rate of death and MI of patients treated with HXHY were no different from those treated with the placebo (P>0.05). Therefore, HXHY is an effective and safe therapy for CHD patients after PCI.
Self‐triggered distributed model predictive control for flocking of multi‐agent systems
Authors: Hu Yanjie , Zhan Jingyuan , Li Xiang
Published: August 2018

This study presents a self‐triggered distributed model predictive control algorithm for the flock of a multi‐agent system. All the agents in a flock are endowed with the capability of determining the sampling time adaptively to reduce the unnecessary energy consumption in communication and control updates. The agents are dynamically decoupled in a flock, and each agent is driven by a local model predictive controller, which is designed by minimising the position irregularity between the agent and its neighbours, velocity tracking errors as well as its control efforts. Moreover, the collision avoidance is considered by introducing constraints in the model predictive minimisation problem. In order to adaptively determine the sampling time, a self‐triggered algorithm is designed by guaranteeing the decrease of the Lyapunov function. Finally, numerical simulations are given to demonstrate the feasibility of the proposed flocking algorithm.
Optimising the power using firework‐based evolutionary algorithms for emerging IoT applications
Authors: Ali Hafiz Munsub , Ejaz Waleed , Lee Daniel C. , Khater Ismail M.
Published: August 2018

Optimising the overall power in a cluster‐assisted internet of things (IoT) network is a challenging problem for emerging IoT applications. In this study, the authors propose a mathematical model for the cluster‐assisted IoT network. The cluster‐assisted IoT network consists of three types of nodes: IoT nodes, core cluster nodes (CCNs) and base stations (BSs). The objective is to minimise transmission, between IoT nodes (IoTs)–CCNs and CCNs–BSs, and computational power (at CCNs), while satisfying the requirements of communicating nodes. The formulated mathematical model is a integer programming problem. They propose three swarm intelligence‐based evolutionary algorithms: (i) a discrete fireworks algorithm (DFWA), (ii) a load‐aware DFWA (L‐DFWA), and (iii) a hybrid of the L‐DFWA and the low‐complexity biogeography‐based optimisation algorithm to solve the optimisation problem. The proposed algorithms are population‐based metaheuristic algorithms. They perform extensive simulations and statistical tests to show the performance of the proposed algorithms when compared with the existing ones.
Virtual impedance‐based virtual synchronous generator control for grid‐connected inverter under the weak grid situations
Authors: Li Gaoxiang , Ma Fujun , Luo An , He Zhixing , Wu Wenhua , Wei Xinwei , Zhu Zhen , Guo Jian
Published: August 2018

In this study, an improved control method of the grid‐connected inverter is presented to enhance the harmonic suppression. The capacitor‐current‐feedback‐based active damping is applied to the LCL‐type grid‐connected inverter, which is controlled in the virtual synchronous generator mode. A virtual‐impedance design method based on modulation signal is proposed, which can not only enhance the stability of the inverter under the weak‐grid situations, but also improve the quality of voltage and current. The transfer function and the impedance model of the system are established to analyse the performance of the methodology. Finally, the experiment results are presented to verify the correctness and effectiveness of the control method.
Hybrid hysteresis current control and low‐frequency current harmonics mitigation based on proportional resonant in dc/ac inverter
Authors: Zhang Haiyu , Li Xiao , Xiao Shunlong , Balog Robert S.
Published: August 2018

In the two‐stage photovoltaic (PV) micro‐inverters, the bipolar hysteresis current control with soft switching for dc/ac inverter can achieve fast dynamic response, robust current regulation and high efficiency even with higher switching frequency. To further reduce the switching losses, unipolar hysteresis current control is desirable. However, it suffers from zero‐crossing distortions and low frequency harmonics in the grid current. To solve those problems, this paper proposes a combined proportional resonant (PR) and hybrid hysteresis current control strategy. By investigating the reasons for zero‐crossing distortions, hybrid hysteresis current control is applied to enable bipolar modulation around the zero‐crossing zone and unipolar modulation in all other zones of the line period. At the same time, due to the wide hysteresis bands for soft switching, low output inductance and non‐negligible sampling intervals from the digital controller, there will be many low frequency harmonics in the spectrum of output inductor current which deteriorates the quality of power absorbed by the grid. Therefore, the PR control may be used as well to mitigate the low frequency harmonics. The theoretical analysis of the proposed solutions are explained in this paper. Detailed simulation and experimental results are presented to verify the feasibility of the proposed control strategy.
Design of a novel routing architecture for harsh environment monitoring in heterogeneous WSN
Authors: Verma Sandeep , Sood Neetu , Sharma Ajay Kumar
Published: August 2018

Wireless sensor network (WSN) has proved to be a hardcore desideratum for the continuous monitoring of hostile areas suffering from devastating forest fires, sudden volcanic eruptions, floods and many more. It can be contemplated by reviewing the state‐of‐the‐art routing strategies, network instability and the delay incurred in data reception at the user end may lead to deplorable circumstances. In this study, a design of a novel routing architecture is proposed for harsh environment monitoring in heterogeneous WSN. It aims to ameliorate the stability period and network lifetime by shortening the communicative distance of nodes from the gateway node and by mitigating the hot‐spot problem in the network. This architecture comprises of a network with multiple gateway nodes (MGNs) (four in this case), placed at equidistant from each other, outside the monitoring area. MGN is enriched with unlimited resources of energy, computation and coverage capabilities. The proposed MGN‐based routing architecture (MRA) also improves the cluster head selection by incorporating node density factor along with energy and distance. Simulations show that MRA outperforms the state‐of‐the‐art protocols, i.e. threshold‐sensitive energy‐efficient delay‐aware routing protocol, Stable and Energy Efficient Clustering Protocol (SEECP), and Distance based Residual Energy‐Efficient Stable Election Protocol (DRESEP) for two different cases of ‘nodes and energy’ fractions at various performance metrics.
Jupiter radio emission induced by Ganymede and consequences for the radio detection of exoplanets
Authors: Zarka P. , Marques M. S. , Louis C. , Ryabov V. B. , Lamy L. , Echer E. , Cecconi B.
Published: August 2018

By analysing a database of 26 yr of observations of Jupiter with the Nançay Decameter Array, we unambiguously identify the radio emissions caused by the Ganymede–Jupiter interaction. We study the energetics of these emissions via the distributions of their intensities, duration, and power, and compare them to the energetics of the Io–Jupiter radio emissions. This allows us to demonstrate that the average emitted radio power is proportional to the Poynting flux from the rotating Jupiter’s magnetosphere intercepted by the obstacle. We then generalize this result to the radio-magnetic scaling law that appears to apply to all plasma interactions between a magnetized flow and an obstacle, magnetized or not. Extrapolating this scaling law to the parameter range corresponding to hot Jupiters, we predict large radio powers emitted by these objects, that should result in detectable radio flux with new-generation radiotelescopes. Comparing the distributions of the durations of Ganymede–Jupiter and Io–Jupiter emission events also suggests that while the latter results from quasi-permanent Alfvén wave excitation by Io, the former likely results from sporadic reconnection between magnetic fields Ganymede and Jupiter, controlled by Jupiter’s magnetic field geometry and modulated by its rotation.
Analytic solution of a magnetized tori with magnetic polarization around Kerr black holes
Authors: Pimentel Oscar M. , Lora-Clavijo Fabio D. , Gonzalez Guillermo A.
Published: August 2018

We present the first family of magnetically polarized equilibrium tori around a Kerr black hole. The models were obtained in the test fluid approximation by assuming that the tori is a linear media, making it is possible to characterize the magnetic polarization of the fluid through the magnetic susceptibility χm. The magnetohydrodynamic (MHD) structure of the models was solved by following the Komissarov approach, but with the aim of including the magnetic polarization of the fluid, the integrability condition for the magnetic counterpart was modified. We build two kinds of magnetized tori depending on whether the magnetic susceptibility is constant in space or not. In the models with constant χm, we find that the paramagnetic tori ( χm >  0) are more dense and less magnetized than the diamagnetic ones ( χm <  0) in the region between the inner edge, rin, and the center of the disk, rc; however, we find the opposite behavior for r >  rc. Now, in the models with non-constant χm, the tori become more magnetized than the Komissarov solution in the region where ∂χm/∂r <  0, and less magnetized when ∂χm/∂r >  0. Nevertheless, it is worth mentioning that in all solutions presented in this paper the magnetic pressure is greater than the hydrodynamic pressure. These new equilibrium tori can be useful for studying the accretion of a magnetic media onto a rotating black hole.
Prediction of the wave power in the Black Sea based on wind speed using artificial neural networks
Authors: Ciortan Sorin , Rusu Eugen
Published: August 2018

The paper proposes a prediction methodology for the significant wave height (and implicitly the wave power), based on the artificial neural networks. The proposed approach takes as input data the wind speed values recorded for different time periods. The prediction of significant wave height is useful both for assessment of wave energy as also for marine equipment design and navigation. The data used cover the time interval 1999 to 2007 and it was measured on Gloria drilling unit, which operates in the Romanian nearshore of the Black Sea at about 500 meters depth.
Economic performance evaluation of natural gas vehicles and their fuel infrastructures
Authors: Hagos Dejene A , Ahlgren Erik O
Published: August 2018

The transition from high carbon-intensity to low carbon-intensity transport fuels entails the development of energy efficient and cost-effective decarbonisation pathways. In this paper, 14 potential natural and renewable gas supply pathways and natural gas vehicles (NGVs) have been selected and evaluated with regards to well-to-tank (WTT) fuel production costs and break-even vehicle added investment costs. NGVs are evaluated for both road- and maritime transport applications with three types of gas engines; dedicated, dual fuel, and high pressure direct injection (HPDI) engines. The results indicate that owing to the alternate gas distribution mechanisms and filling stations configuration there exist a substantial fuel production cost differences between the selected gas pathways. Despite its long-distance shipping and distribution, imported LNG showed significant production cost advantage over compressed natural gas (CNG) and liquefied renewable natural gas (LRNG) pathways. Evaluating the current economic performances, all NGVs are found to be competitive corresponding to gasoline cars, but not compared to diesel cars due to the lower price gap between CNG and diesel. In the heavy-duty vehicle and passenger vessel segments, however, owing to the high price gap between LNG and diesel/marine gas oil (MGO), all NGVs and LNG passenger vessels showed high competitiveness compared to their conventional counterparts.
Very-short term solar power generation forecasting based on trend-additive and seasonal-multiplicative smoothing methodology
Authors: Eroshenko Stanislav , Khalyasmaa Alexandra , Valiev Rustam
Published: August 2018

In conditions of development of generating facilities on renewable energy sources, the technology runs up to uncertainty in the operational and short-term planning of the power system operating modes. To date, reliable tools for forecasting the generation of solar power stations are required. This paper considers the methodology of operational forecasting of solar power stations output based on the mathematical apparatus of cubic exponential smoothing with trend and seasonal components. The presented methodology was tested based on the measuring data of a real solar power station. The average forecast error was not more than 10% for days with variable clouds and not more than 3% for clear days, which indicates the effectiveness of the proposed approach.
Hemp is the Future of Plastics
Authors: Modi Ali Asghar , Shahid Rehmatullah , Saeed Muhammad Usman , Younas Tanzila
Published: August 2018

Plastic is the world's most adaptable material. From bikes to food wraps and from jets to pencils, you can make anything and everything from plastics. With the infinite number of uses, plastic also have some devastating impacts on our planet. Most plastics produced today are made using petroleum-based compounds that release harmful gases into the atmosphere. Waste solutions are inefficient, and harmful by-products toxic our land, water and wildlife. Yet, consider the possibility that there was a way to deal with deliver the greater part of what we utilize causes a negative greenhouse impact, is sustainable and biodegradable and has just about an indistinguishable cost to our present techniques. Meet Hemp plastic, an only plastic that's 100% biodegradable in nature if produce by using only Hemp plant. Hemp plant consumes 4 times more carbon dioxide then other plants from atmosphere. The fiber we can produce from hemp is stronger than the conventional fiber we are using these days. This paper is intended to show numerous benefits of using hemp for the manufacturing of biodegradable plastic (HEMP PLASTIC) rather than conventional plastics.