bluuebunny/crossref_metadata_2025 huggingface dataset:
Clustering Titik Panas Menggunakan Algoritma Agglomerative Hierarchical Clustering (AHC)
Authors: Kusumastuti Rajnaparamitha , Bayunanda Elfandry , Rifa’i Anggi Muhammad , Asgar Muhamad Ryandy Ghonim , Ilmawati Fahma Inti , Kusrini Kusrini
Published: December 2022

Kebakaran hutan di Indonesia setiap tahunnya masih sering terjadi. Dalam menanggulangi kebakaran hutan sendiri, para peneliti belakangan ini semakin fokus untuk melakukan pengembangan sistem yang mampu melakukan prediksi kebakaran hutan. Selain melakukan prediksi mengenai kebakaran hutan, antisipasi yang dapat dilakukan untuk membantu menangani pencegahan kebakaran hutan salah satunya adalah melakukan pengelompokkan terhadap wilayah yang memiliki potensi kebakaran. Pada penelitian ini melakukan Clusterisasi titik panas (hotspot) untuk membagi wilayah yang berpotensi untuk terbakar. Pengelompokkan wilayah dilakukan berdasarkan cluster kebakaran rendah, sedang, dan tinggi. Clusterisasi wilayah dilakukan menggunakan algoritma Agglomerative Hierarchical Clustering (AHC). Data yang digunakan pada perhitungan ini menggunakan wilayah Kalimantan Barat dengan menggunakan variable longitude, latitude, frp, confidence, dan curah hujan untuk menentukan clustering wilayah kebakaran. Tujuan dalam penelitian ini adalah untuk mengcluster titik panas kebakaran hutan berdasarkan wilayah yang berpotensi terjadi kebakaran hutan sehingga memiliki peluang untuk segera ditindaklanjuti. Dari hasil pengujian diperoleh pembentukan 2 cluster yang dimana menunjukkan terbentuk 2 pengelompokkan titik panas (hotspot) pada kelas sedang dan tinggi dengan nilai evaluasi silhouette coefficient 0,771.

Kata kunci— Clustering, titik panas, Agglomerative Hierarchical Clustering
INSTRUMEN KEBIJAKAN MONETER ISLAM DI INDONESIA
Authors: Awal Nurul
Published: December 2022

Instrumen pengendalian moneter pada sistem ekonomi konvensional terbukti Tidak efisien dan tidak lebih stabil dibandingkan dengan instrumen pengendalian Moneter pada sistem ekonomi Islam. Penerapan instrumen moneter syariah yangB langsung dengan instrumen moneter konvensional memiliki dampak Yang cukup signifikan terhadap pengendalian inflasi (stabilitas harga) di Indonesia. Namun, sebenarnya bagaimana konstribusi instrumen moneter syariah secara parsialTe engendalian inflasi belum diketahui pasti.
Ume LE'U atau ume kbubu Insana
Authors: SELAN CAMELIA FEBRIYANI
Published: December 2022

Ume Le, u atau ume kbubu merupakan tempat menenun dan menerima tamu
Meneropong Personality Guru PAK Berdasarkan 2 Timotius 2:1-13
Authors: Purwanti Kayla Dharma
Published: December 2022

Kepribadian guru merupakan fakor terpenting bagi keberhasilan belajar siswa-siswi. ataukah akan menjadi perusak atau penghancur bagi masa depan siswa-siswi terutama bagi siswa-siswi yang masih kecil (tingkat dasar) dan mereka yang sedang mengalami kegoncangan jiwa (tingkat menengah. Penelitian ini menggunakan kajian literatur teks Alkitab dalam 2 Timotius 2:1-13 yang memuat tentang prinsip memuridkan dari Paulus kepada Timotius. Pendekatan yang digunakan adalah kualitatif, dengan menerapkan metode deskriptif analisis pada teks 2 Timotius 2:1-13, sehingga didapati beberapa karakteristik tentang kepribadian guru Pendidikan agama Kristen. Hasil yang ditemukan adalah kepribadian guru Pendidikan agama Kristen adalah merupakan kepribadian guru yang rela berkorban, taat, dan tekun.
Pengembangan Media Video Pembelajaran Ilmu Pengetahuan Sosial Pada Siswa Sekolah Dasar
Authors: nadara Amanda alaisya
Published: December 2022

pengembangan media ini bertujuan untuk menghasilkan suatu produk media video pembelajaran yang valid dan efektif
HUBUNGAN ANTARA DUKUNGAN SOSIAL TEMAN SEBAYA DENGAN IDENTITAS DIRI SISWA KELAS VII SMPN 1 BARABAI, HULU SUNGAI TENGAH.
Authors: putra Triwobowo Agung
Published: December 2022

Untuk mengetahui hubungan antara dukungan sosial teman sebaya dengan identitas dirisiswa kelas VII SMP Negeri 1 Barabai Kecamatan Barabai Darat Kabupaten Hulu Sungai Tengah TahunAjaran 2019/ 2020. Populasi penelitian ini adalah seluruh siswa kelas VII sebesar 160 siswa. Sampeldalam penelitian ini sebesar 50 siswa dengan menggunakan teknik quota random sampling. Metodepengumpulan data dalam penelitian ini adalah angket. Teknik analisa data dengan menggunakananalisis korelasi product moment. Hasil penelitian menunjukkan bahwa ada hubungan yang positifdan signifikan antara dukungan sosial teman sebaya dengan identitas diri siswa kelas VII denganmengetahui nilai rhitung sebesar 0,565 lebih besar dari rtabel 0,279 pada taraf signifikansi 5%.Dengan demikian semakin tinggi dukungan sosial teman sebaya kepada siswa maka semakin tinggiidentitas diri yang dimiliki siswa, sebaliknya semakin rendah dukungan sosial teman sebaya padasiswa maka semakin rendah pula identitas diri siswa.Dengan arti lain bahwa tinggi rendahnya identitas diri siswa dapat dipengaruhi oleh tinggirendahnya pemberian dukungan sosial teman sebaya terhadap siswa. Implikasi dari penelitian iniadalah bahwa adanya hubungan yang positif dan signifikan antara dukungan sosial teman sebayadengan identitas diri siswa memberikan perhatian, motivasi, bimbingan dan peran dari berbagaipihak baik di sekolah maupun di rumah sangat diperlukan dalam meningkatkan dukungan sosial danmenumbuhkan rasa percaya diri sehingga identitas diri siswa menjadi lebih baik.
Differential expression of ATP2A1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: December 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of ATP2A1, encoding ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, in the skeletal muscle of patients with ALS. ATP2A1 was also differentially expressed in fibroblasts isolated from patients with ALS. ATP2A1 transcript was present at significantly lower levels in ALS patient skeletal muscle as compared to control skeletal muscle. These analyses will begin to define the transcriptional landscape of ALS.
Menilik Sinkretisme Dalam Konteks Misi Perintisan Jemaat Baru
Authors: Isabel Sarah
Published: December 2022

Sinkretisme menjadi masalah besar bagi para perintis yang tidak menyukai paham ini. Dimana hal tersebut berdampak buruk bagi budaya-budaya yang dihadapkan dengan Injil. Injil mengabaikan dan menolak semua budaya. Hal ini akan membuat untuk Injil akan sulit untuk dikomunikasikan kepada orang-orang yang memiliki budaya tersebut. Oleh karena itu penulis mengangkat data-data dari pelayanan rasul Paulus di dalam Alkitab dan menunjukan kepada para pembaca atau para perintis bahwa sinkretisme tidak selalu berdampak buruk bagi misi perintisan jemaat baru. Pembahasan mengenai sinkretisme ini juga bertujuan guna mendorong para perintis untuk tidak menolak nilai-nilai budaya yang ditemui dalam dunia perintisan. Injil di asimilasikan ke dalam budaya sehingga menjadi satu dengan budaya, namun batasannya adalah Yesus diatas segalanya dan Yesus Kristus menjadi tolok ukur untuk menilai budaya mana yang harus ditiadakan dan mana yang dapat dipakai. Penulis melakukan kajian pustaka dan memakai sumber-sumber dari Alkitab untuk dijadaikan sebagai bahan bukti dari pembahasan ini. Hasilnya adalah benar bahwa sinkretisme tidak selalu berdampak buruk terhadap misi perintisan jemaat baru. Asal batasannya adalah Yesus sebagai satu-satunya Tuhan dan menjadi tolok ukur dari tatanan kebudayaan. Juga, dalam misi perintisan harus membawa rekan kerja,bukan hanya sebatas membatu bekerja dalam pelayanan, melainkan juga sebagai teman diskusi tentang batasan dari sinkretisme.
Examining the prevalence and correlates of probable depression and anxiety among Chinese males diagnosed with gynecomastia
Authors: Song Baoji , Bi Kaiwen , Sun Pei
Published: December 2022

A growing body of literature in Western countries has found that males with gynecomastia, or excessive breast tissue growth among males, may be vulnerable to low self-esteem, body image issues, and psychological distress. However, there was a lack of studies associating gynecomastia-related social withdrawal behaviors and discrimination with distress. In addition, while China accounts for approximately 20% of the world population, surprisingly few research investigated the mental health burden of Chinese with gynecomastia. Our study represents the first study to investigate the prevalence and under-studied correlates of distress among a large sample of Chinese (N = 407) diagnosed with gynecomastia. We found that 41.5% and 30.2% of participants were affected by probable depression (CESD-20 >= 16) and anxiety (GAD-7 >= 7). Furthermore, 80.3% of participants reported being teased or experiencing discrimination because of their breasts. Many participants (22.4% to 65.8%) reported high frequencies (at least almost always) of social withdrawal and hiding behaviors (e.g., putting on extra clothes, avoiding going to public spaces) because of concerns over their enlarged breasts. Correlates of distress included higher gynecomastia-related social withdrawal and hiding behaviors and surprisingly not experiencing gynecomastia-related discrimination (vs. experiencing). Clinical implications and future directions are discussed.
SCIENCE, TECHNOLOGY, AND SOCIETY KETERKAITAN ILMU PENGETAHUAN, TEKNOLOGI DAN MASYARAKAT PADA PEMBELAJARAN IPS
Authors: Sari Mita Puspita
Published: December 2022

catatan terkait dengan Science, Technology, And Society Keterkaitan Ilmu Pengetahuan, Teknologi Dan Masyarakat Pada Pembelajaran Ips
STABILITAS SISTEM KEUANGAN (SSK) DAN STABILITAS MONETER
Authors: istiqomah Bunga sahila hizbul
Published: December 2022

Stabilitas Sistem Keuangan (SSK) sebenarnya belum memiliki definisi baku yang telah diterima secara internasional. Oleh karena itu, muncul beberapa definisi mengenai SSK yang pada intinya mengatakan bahwa suatu sistem keuangan memasuki tahap tidak stabil pada saat sistem tersebut telah membahayakan dan menghambat kegiatan ekonomi. Di bawah ini dikutip beberapa definisi SSK yang diambil dari berbagai sumber:
KEBIJAKAN MONETER ISLAM DI INDONESIA
Authors: istiqomah Bunga sahila hizbul
Published: December 2022

Islam memiliki kebijakan moneter tersendiri yang berbeda dengan system ekonomi lainnya. Pada aspek tujuan islam tidak hanya menekankan equilibrium antara permintaan dan penawaran uang akan tetapi juga mengupayakan terjadinya pemerataan dengan prinsip keadilan dan persaudaraan, sehingga tercipta distribusi kekayaan dan pendapatan secara adil pula.
Differential expression of PCDHB5 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: December 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published and public data (3, 4). We found significant differential expression of PCDHB5, encoding protocadherin beta 5, in the skeletal muscle of patients with ALS. PCDHB5 was also differentially expressed in the induced pluripotent stem cell (iPSC)-derived motor neurons of patients with ALS. PCDHB5 transcript was present at significantly higher levels in ALS patient skeletal muscle as compared to control skeletal muscle. These analyses will begin to define the transcriptional landscape of ALS.
Educated Choices Program: Living Lab 2022 Annual Report
Authors: Bryant Christopher John
Published: December 2022

We present an impact evaluation of The Educated Choices Program (ECP), a non-profitwhich delivers educational presentations on the impact of food choices with the aim ofreducing animal product consumption and promoting plant-based eating.We used survey data from over 5,000 presentation viewers to assess the overall impact,investigate viewers’ motivations, barriers, and comments on plant-based diets, and assessthe impact of different presentations, audiences, and delivery methods.Our major findings suggest that:1. ECP presentations reduce consumption of animal products. ECP viewers were 67%more likely to intend to change their diets compared to a control group. Viewers whohad seen an ECP presentation previously were 20% more likely to be meat-reducers,and 10% more likely to avoid meat entirely.2. Viewers’ major motivations to change were health, the environment, and animals,while major barriers included taste, family diets, and cost. Facts about animalslaughter were among the most memorable despite making up a relatively smallproportion of the presentation content.3. Recommending that students adopt one meat-free meal per day is perceived asachievable, and is likely to be more impactful than other methods.4. Female and non-binary viewers, older teenagers, and those in relevant classes aremost likely to intend to change their diets.5. The Healthful Eating presentation was the most impactful, while in-classpresentations are more impactful than those delivered online.
Differential expression of DNASE2 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: December 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published data (3, 4). We found significant differential expression of DNASE2, encoding deoxyribonuclease 2, lysosomal, in the skeletal muscle of patients with ALS. DNASE2 was also differentially expressed in primary lower motor neurons isolated from patients with ALS. DNASE2 transcript was present at significantly lower levels in ALS patient skeletal muscle as compared to control motor neurons. These analyses will begin to define the transcriptional landscape of ALS.
EKONOMI MONETER ISLAM PADA MASA DEPAN
Authors: Awal Nurul
Published: December 2022

Moneter di masa depan masih bisa seperti moneter di masa lalu yaitu menggunakan dinar dan dirham sebagai alat untuk mencetak uang, dalam hal ini emas yang berperan penting dalam mengontrol jum;lah pencetakan uang di setiap negara agar dapat menciptakan stabilitas negara yang baik. Penggunaan dinar dan dirham ini akan terjadi ketika para umat muslim tetap optimis akan terjadi. Karena sesungguhnya penggunaan dinar dan dirham telah ada sebelum manusia itu sendiri ada sehingga sebagai umat masa depan kita harus selalu optimis bahwa stabilitas penggunaan dinar dan dirham akan terjadi di masa depan dengan baik. Segala bentuk optimis manusia tentang penggunaan dinar dan dirham di masa yang akan datang itu bisa terjadi meskipun pada akikatnya penggunaannya akan mengalami beberapa tantangan yang dihadapinya. Meski begitu tantangan tersebut tidak akan membuat penggunaan dinar dan dirham tidak baik.
EKONOMI MONETER ISLAM MASA DEPAN
Authors: istiqomah Bunga sahila hizbul
Published: December 2022

Sistem moneter saat ini masih terpaku pada tingkat suku bunga. Maka dari itu dalam menerapkan sistem moneter dengan prinsip-prinsip islam, ada 3 fokus utama yang harus dilakukan, yaitu:a)Penyelarasan Prinsip Islamb)Permodalan Sistem Moneterc)Peran dan Dukungan Pemerintah
NATIONAL COUNCIL FOR THE SOSIAL STUDIES (NCSS) : MANUSIA, TEMPAT DAN LINGKUNGAN DALAM PEMBANGUNAN KARAKTER DI DUNIA PENDIDIKAN
Authors: Andini
Published: December 2022

Pendidikan karakter merupakan upaya untuk menerapkan nilai-nilai agama, Moralitas, etika siswa melalui ilmu, juga dengan bantuan orang tua, guru sebuah komunitas yang sangat penting bagi pembentukan dan pengembangan karakter para pesertanya
Tata Kelola Pemerintah Dalam Pemberantas Koropsi
Authors: Ulfah Maria
Published: December 2022

Korupsi dalam Bahasa latin disebut corruption-corruptus, dalam Bahasa belanda disebut corruptive, dalam Bahasa inggris disebut corruption, dalam Bahasa sansekerta di dalam naskah kuno negara kertagama disubut corrupt, arti harpiahnya menunjukkan kepada perbuatan yang rusak, busuk, bejat, tidak jujur yang disangkutpautkan dengan keuangan. menggunakan uang yang tidak tepat, memalsukan dokumen dan menggelapkan uang, mengalirkan uang lembaga ke rekening pribadi, menggelapkan pajak, menyalahgunakan dana, Menggunakan wewenangdan intimidasi, menyiksa, penganiayaan, memberi ampun dan grasi tidak pada tempatnya. Menipu dan mengecoh, mem beri kesan yang salah, mencurangi, memperdaya dan memeras. Menggunakan informasi internal dan informasi rahasia untuk kepentingan pribadi, membuat laporan palsu. Menghindari pajak, meraih laba berlebih-lebihan, Menerima hadiah, uang jasa, uang pelicin dan hiburan, jalanan yang tidak pada tempatnya. Berhubungan dengan organisasi kejahatan, operasi pasargelap.
ANALISIS MAKNA SIMBOLIS "MAKOSU" DALAM RESEPSI PERNIKAHAN PADA MASYARAKAT DESA RETRAEN KECAMATAN AMARASI SELATAN KABUPATEN KUPANG. PROVINSI NUSA TENGGARA TIMUR
Authors: passu marfin amidonti
Published: December 2022

resepsi pernikahan pada masyarakat desa retraen kecamatan amarasi selatan kabupaten kupang yang bertujuan untuk penyambutan pengantin
Peran Guru PAK dan Orang Tua dalam Membentuk Kerohanian Siswa
Authors: Sianipar Sudiro Putra
Published: December 2022

Potensi karakter yang baik dimiliki manusia sebelum dilahirkan, tetapi potensi tersebut harus terus-menerus dibina melalui sosialisasi dan pendidikan sejak usia dini. Mengembangkan dan mengiplementasikan karakter bukan merupakan sebuah proses instan pendidikan karakter membutuhkan waktu, tenaga, dan banyak hal lain yang saling mendukung untuk membentuk dan mengembangkan tatanan karakter yang baik agar tercipta generasi yang memiliki pola pikir dan pandangan yang luas dan bijaksana sehingga melahirkan generasi yang berkarakter unggul. Penelitian ini dilakukan untuk mengetahui sejauhmana peranan orangtua dan guru Pendidikan Agama Kristen dalam membentuk karakter kerohanian peserta didik. Untuk memperoleh data dalam penelitian ini, penulis menggunakan pendekataan kualitatif deskriptif dengan metode penelitian library research. Adapun hasil kajian penelitian ini menunjukkan bahwa: dengan adanya sinergisme yang baik dari orangtua dan guru Pendidikan Agama Kristen di sekolah akan mempermudah dalam membentuk kepribadian dan karakter kerohanian peserta didik yang mandiri serta dewasa dalam menjalani kehidupannya sebagai makhluk individu sekaligus makhluk sosial.
ARTIKEL HUSNATUL HASANAH2110115220029 PRDUKSI KERUPUK RANGGINANG ROFIF ALWI (RA) TABAT PADANG
Authors: HASANAH HUSNATUL
Published: December 2022

Teknis pengolahan makanan khas nusantara yang satu ini cukup sederhana. Beras ketan yang telah dibersihkan kemudian dikukus dalam air mendidih. Kemudian, masukan penyedap rasa secukupnya dan aduk sampai merata. Setelah dirasa bumbu menyerap, beras ketan ditiriskan sebelum akhinya dibentuk sesuai selera. Setelah itu, hasil bentukan rengginang dijemur di tengah terik matahari.
TARIAN ADAT PEDO'A DAN LEDO DI KABUPATEN SABU RAIJUA
Authors: Lomi Erwin Frangky
Published: December 2022

Tarian Adat Pedo'a Dan Ledo Merupakan Tarian Yang Sangat Populer Di Kalangan Masyarakat Sabu Raijua. Tarian Ini Bertujuan Untuk Mempererat Tali Kekeluargaan
Waktu, Kontinuitas dan Perubahan
Authors: Sari Nila
Published: December 2022

Ips adalah satu diantara mata pelajaran disekolah yang banyak memanfaatkan lingkungan sekitar sebagai sarana belajar. Lingkungan sebagai sarana belajar tentunya harus memberikan manfaat yang besar bagi peserta didik. Lingkungan sekitar yang bisa digunakan sebagai sarana belajar satu diantara nya adalah pasar. Pasar merupakan tempat terjadinya transaksi jual beli antara penjual dan pembeli. Dipasar peserta didik dapat melihat kegiatan produksi, distribusi, dan konsumsi. Adanya kegiatan tersebut membuat peserta didik mengetahui terkait materi ekonomi yang terdapat dalam pembelajaran ips. Dengan begitu, pasar dapat dimanfaatkan sebagai laboratorium ips karena dapat memberikan informasi yang tentunya dapat menjadi sumber belajar ips.
TARIAN ADAT PEDO'A DAN LEDO DI KABUPATEN SABU RAIJUA
Authors: BANA ASRIANI
Published: December 2022

Tarian Adat Pedo'a dan ledo merupakan Tarian yang sangat populer di kabupaten sabu raijua.Tarian ini bertujuan Untuk Mempererat kekeluargaan.
UAS KRITIK SENI LISTIANI
Authors: kapitan Listiani afilia
Published: December 2022

Dalam pengertiannya musik adalah suara yang disusun demikian rupa sehinggamengandung irama, lagu, dan keharmonisan terutama suara yang dihasilkan dari alat-alat yang dapat menghasilkan irama. Beberapa tahun terakhir perkembangan musik di Indonesia berkembang dengan cepat. Banyak musisi-musisi maupun band-band yang bermunculan tiap tahunnya dengan membawa ciri mereka masing-masing. Industri-industri musik juga mulai bergerak dengan memberikan kontrak label mereka. Bahkan stasiun-stasiun televisi baik swasta maupun negeri juga memberikan tayangan hiburan musik kepada masyarakat
Pasar Monopoli
Authors: AR Ashra
Published: December 2022

Secara etimologi kata “monopoli” berasal dari kata Yunani yaitu monos yang berarti sendiri dan polein yang berarti penjual. Dari akar kata tersebut secara sederhana banyak orang memberi pengertian monopoli suatu kondisi dimana hanya ada satu penjual yang menawarkan (supply) atas barang dan jasa tertentu.
UNDANG-UNDANG NOMOR 23 TAHUN 2014 YANG BERKAITAN DENGAN KEWENANGAN PEMERINTAH OTONOMI DAERAH
Authors: Puspita Ezanadia
Published: December 2022

Dalam praktek pelaksanaan otonomi daerah di Indonesia, Pemerintahan Daerah mempunyai kewenangan untuk mengatur sendiri daerahnya dengan adanya pembagian kewenangan yang diatur dalam Undang-Undang Nomor 23 Tahun 2014 tentang Pemerintahan Daerah. Kewenangan tersebut adalah urusan-urusan yang terkait dengan urusan konkuren yang terdiri dari urusan wajib dan pilihan. Hubungan pemerintah pusat dan pemerintah daerah pada hakikatnya adalah pembagian kewenangan dalam penyelenggaraan pemerintahan. Pembagian kewenangan ini telah diatur dalam berbagai peraturan perundang-undangan tentang pemerintahan daerah. Setidaknya terdapat sembilan peraturan perundang-undangan yang mengatur tentang pemerintahan daerah. Peraturan perundang-undangan tersebut mengatur apa saja yang menjadi kewenangan pemerintah pusat dan apa saja yang menjadi kewenangan pemerintah daerah. Peraturan perundang-undangan itu juga yang menentukan corak dan model hubungan pemerintah pusat dan pemerintah daerah.
Transformasi Pendidikan Ilmu Pengetahuan Sosial dalam Menghadapi Era Revolusi Industri 4.0 Koneksi Global
Authors: Putri Bayshera Andinda
Published: December 2022

Era Revolusi Industri 4.0 telah menjadi fenomena penting di berbagai bidang, termasuk industri pelatihan Siswa tidak boleh hanya menggunakan masalah saat ini teknologi digital,namun kualitas sumber daya manusia masih perlu ditingkatkan untuk dapat melakukannya beradaptasi dengan perubahan. skor Studi ini menunjukkan bahwa pelatihan IPS adalah alat untuk menghadapi perubahan Pendidikan IPS pada era sekarang ini bukan sekedar konsep atau teori, melainkan implementasi dari pendidikan IPS. menjadi panduan bagi siswa untuk memecahkan masalah sosial. Isu-isu global dapat menarik perhatian masyarakat dunia dan memiliki implikasi yang luas termasuk mendorong kelompok masyarakat untuk membuat keputusan yang berani.Kepentingan pendidikan IPS adalah untuk mendukung semangat kewarganegaraan yang baik,untuk dapat bereaksi dengan baik terhadap permasalahan global tersebut pembelajaran yang lebih bermakna untuk mengurangi dampak negatif dari permasalahan global untuk tumbuh Pendidikan dalam IPS merupakan penyederhanaan dan pilihan disiplin Ilmu sosial dan humaniora dan kegiatan akar rumput yang terorganisir dan disiapkan secara ilmiah dan psikologis untuk tujuan pendidikan. Di tingkat kelas, guru dan dosen perlu meningkatkan kapasitasnya melalui pelatihan dan kreatif dalam melaksanakan pembelajaran bermakna untuk berusaha menghasilkan warga negara yang baik dapat dilaksanakan.
Sociodemographic risk factors for the persistence of harmful alcohol use: A pooled analysis of prospective cohort studies
Authors: Ehrnrooth Anna , Gluschkoff Kia , Jokela Markus , Komulainen Kaisla
Published: December 2022

Purpose: Previous research suggests several sociodemographic risk factors for the persistence of harmful alcohol use. However, the evidence is limited due to short follow-up times, retrospective reporting and selected study populations. We pooled data from prospective cohort studies to systematically evaluate whether the sociodemographic risk factors differ between the incidence and persistence of harmful alcohol use.Methods: Data were from six prospective cohort studies from the US, UK and Japan (n=28,394). We conducted a two-stage meta-analysis to examine the associations of seven sociodemographic risk factors (sex, age, ethnicity, relationship status, educational attainment, smoking and psychological distress) with the incidence and persistence of harmful alcohol use. Tests of heterogeneity were used to evaluate whether the associations differ between the incident and persistent use. Results: Male sex, younger age, living without a partner, higher education, smoking, and psychological distress were associated with a greater risk of both the incidence and the persistence of harmful alcohol use in mutually adjusted models (ORs=0.97-1.91). There were no differences in the associations of these risk factors with incident and persistent use, except that the association of psychological distress was greater with incident use compared to persistent use (p for heterogeneity <0.05). Conclusions: These findings suggest that the incidence and persistence of harmful alcohol use share a similar set of sociodemographic risk factors in the general population.
C-reactive protein and cognition: Mediation analyses with brain morphology in the UK Biobank
Authors: Mendelson Daniel , Mizrahi Romina , Lepage Martin , Lavigne Katie M.
Published: December 2022

Cognitive impairments and abnormal immune activity are both associated with various clinical disorders. The association between C-Reactive protein (CRP), a marker associated with inflammation, and cognitive performance remains unclear. Further, mechanisms potentially linking CRP to cognition are not yet established. Brain structure may well mediate this relationship: immune processes play crucial roles in shaping and maintaining brain structure, and brain structure and function drive cognition. The UK Biobank is a large cohort study with extensive assessments, including high-sensitivity serum CRP levels, brain imaging, and various cognitive tasks. With data from 39,200 UK Biobank participants, we aimed first to determine the relationship between CRP and cognitive performance, and second, to assess metrics of brain morphology as potential mediators in this relationship. Participants were aged 40 to 73 at initial assessment and were mostly Caucasian. After accounting for potential covariates (e.g., age, sex, medical diagnoses, use of selective-serotonin reuptake inhibitors), we found CRP levels to have small, negative associations with fluid intelligence (b = -0.03, 95%CI[-0.05,-0.02], t(14381) = -3.62, pcor = .004), and numeric memory (b = -0.03, 95%CI[-0.05,-0.01], t(14366) = -3.31, pcor = .007). We found no evidence of brain morphology mediating these relationships. Our findings from this large sample suggest that serum-assessed CRP is of marginal importance for cognitive performance in mid-to-late aged Caucasians; the small effect sizes of statistically significant associations provide context to previous inconsistent results. The seeming lack of involvement of brain morphology suggests that other brain metrics (e.g., connectivity, functional activation) may be more pertinent to this relationship. Future work should also consider CRP levels measured in the central nervous system and/or other cytokines that may better predict cognitive performance in this population.
Life trajectories and social change in mental health: A study of change in general mental health and diagnosed depression in Germany
Authors: van Leeuwen Jos , Leopold Liliya
Published: December 2022

The prevalence of diagnosed mental disorders has increased in many modern societies, particularly among younger people. This is often attributed to a rise in mental health problems, but empirical evidence supporting this interpretation is limited. An alternative interpretation attributes this increase not to worsening mental health but to a rise in clinical diagnoses for given levels of mental health. The present study evaluated both interpretations by comparing a measure of multidimensional general mental health (Mental Component Scale) with a measure of self-reported diagnosed depression using data from the German Socioeconomic Panel (SOEP) collected between 2002 and 2020 (n = 66,332 individuals, N = 331,868 observations). Based on hierarchical growth curve models, we examined individual change with age and social change across cohorts in both outcome measures. Results on life course trajectories showed that in early and middle adulthood improving general mental health was accompanied by an increasing prevalence of diagnosed depression. Both measures peaked around age 65 to 70 and declined thereafter. An equally sharp contrast between both measures was found for social change across cohorts: cohort improvements in general mental health were accompanied by a rise in diagnosed depression. Age and cohort patterns for both measures were broadly similar for men and women. These results indicate that an increase in the prevalence of diagnosed depression may not imply a decline in general mental health. Possible mechanisms include changes in the stigma of mental disorder, changes in treatment-seeking behavior, and direct positive effects of treatment on general mental health.
Conceptualization for intended action: A dynamic model
Authors: Kaipainen Mauri , Hautamäki Antti , Parthemore Joel
Published: December 2022

Concepts are the building blocks of higher-order cognition and consciousness. Building on Conceptual Spaces Theory (CST) and proceeding from the assumption that concepts are inherently dynamic, this paper provides historical context to and significantly elaborates the previously offered Iterative Subdivision Model (ISDM) with the goal of pushing it toward empirical testability. The paper describes how agents in continuous interaction with their environment adopt an intentional orientation, estimate the utility of the concept(s) applicable to action in the current context, engage in practical action, and adopt any new concepts that emerge: a largely pre-intellectual cycle that repeats essentially without interruption over the conceptual agent's lifetime. This paper elaborates utility optimization by establishing three constraints on concept formation/evaluation—non-redundancy, distinctiveness and proportionality—embedding them in a quasi-mathematical model intended for development into a formal logic. The notion of a distinctor—a quality dimension of the conceptual space in focus at any given time, used for making what we call a difference distinction—is key. The primary contribution of the revised ISDM is the way it relates concepts to action via utility optimization/actualization and the way it describes the emergence of quality dimensions through trial-by-action (trial and error), something previous presentations of CST have failed to address.
The Cycle of Rule: Existential Risks, Continuity Of Governance, And Conflict-Based Preservation
Authors: Midha Joshua
Published: December 2022

This paper argues for a perspective on the cycle of governance in past circumstances and in the provided future. It highlights a certain balance between conflict and peace which must exist in order to enforce long-term political stability. The need for conflict can be divided up into three portions which also highlight the areas of risk for any failure of government. The first is infrastructural conflict which deals with internal issues and changes as a method of extending governance. The second is ultrastructural conflict which highlights a necessary presence of external pressure—whether that be militarily, politically, or socially. And the final portion argues for a balance of socially influential conflict which comes from within the republic’s penumbra and requires necessary changes or conflict such as the population’s exposure to social and political turbulence to create a long-term endurance. These three factors define the larger need for conflict and change to enforce longevity and sustainability within a governing body. By tackling historical circumstances, and larger philosophies of governance on a conceptual level and with behavioral theory, this paper provides a comprehensive outlook regarding the need for conflict and aims to highlight a misconception regarding peace being the sole force of sustenance within governing a sovereign body politic.
Toxicity of Toddalia asiatica is associated with microcephaly and hypochondroplasia in mice
Authors: Joseph Gichuru M , Maina Mwonjoria JK , David Mburu N , Nelson Menza C
Published: December 2022

In Kenya various plant extracts are widely used as folklore remedies for various ailments including malaria etc. However, use of these traditional remedies poses a risk to the users due to the scarcity of data on their safety including their teratogenic potential. Hence this study evaluated the teratogenic and sub-acute toxic effects of methanol: dichloromethane extract of Toddalia asiatica in animal mice. In the study, young female mice aged between 6-7weeks were mated with mature males and conception confirmed using vaginal plug, maternal weight and breast enlargement. Administration of the dosed of the plant extract and controls was done from day 6 through 15 of gestation. The mice were euthanized on the 19th day of gestation. The weight of the gravid uterus, pups, number of pups and gross examination to identify any physical abnormalities was done. In the toxicity study male mice aged between 6-7 weeks received oral administration of high doses of plant extract and the control daily for 28days. On the 29th day animals were sacrificed, cardiac puncture conducted and collected blood for hematology and biochemistry analysis. The data obtained was analyzed using one way ANOVA followed by Tukey as the post hoc test. Statistical significance was set p < 0.05. The extracts caused significant reduction (p<0.001) in head size, birth weights and length of the limbs but no effects on hematology parameters. Hence the plant extract exhibited teratogenic effects and thus should be used with care during pregnancy.
The oral subacute toxicological activity of hydroalcoholic extract of Moringa oleifera Lam. (Moringaceae) growing in South West of Burkina Faso in Wistar rats
Authors: Somé Andouormwine Abel , Dabiré Prosper Anankpètinan , Da Filpkière Léonard , Sawadogo Stanislas , Ouédraogo Maurice , Bayala Balé
Published: December 2022

Acute and Subacute toxicity investigations were carried out to evaluate the safety of M. oleifera leaf used in the treatment of various diseases and in nutrition. Five groups of 10 rats of both sex (5rats/sex) were constituted. The first group served as control and received distilled water 10mL/kg/ day while groups II, III, and IV respectively received orally and daily the ethanolic extract of Moringa oleifera at doses 200, 400 and 800mg/kg bw for 4 weeks. The last group (V) considered as satellite group received also received the EEM 800mg/kg daily and orally for 4 weeks. At the end of the test period (4 weeks), the animals of this last group were observed without any treatment for 2 weeks again before their sacrifice in order to study the persistence or the disappearance of possible toxic effects of the extract. The rat was segregated according to gender and housed in cages of 5 rats. In Subacute toxicity investigated with Wistar rats, no mortality was recorded during the experimentation period. Moreover, there was no significant change in weight gain, relative organ weight, or hematological and serum chemical parameters except in a group of female animals where we noticed a reversible decrease in serum ALAT level (at 400mg/kg), total cholesterol (at 400mg/kg) and LDL level (at 800mg/kg) compared to ED group. The histopathological examination had shown some differences between the treated group and the control group that cannot be considered treatment-related.
Exploring the Parameters of Verb Agreement in Majhi
Authors: Dhakal Dubi Nanda
Published: December 2022

This paper discusses a number of parameters which trigger verb agreement in Majhi, an Indo-Aryan language spoken in Nepal. Like some Indo-Aryan neighbours, Majhi takes account of ranges of facts in the verb agreement. The verb is not only marked for agreement with one nominal phrase in a clause, but also encodes inflectional features of both subject and object simultaneously in transitive and ditransitive verbs by employing portmanteau suffixes. The features that control the agreement include person, number, honorificity, gender, and case roles of nouns.
Coding Grammatical Relations in Dhimal
Authors: Khatiwada Karnakhar
Published: December 2022

Grammatical relations play a vital role not only in the grammar of simple clauses but also in major syntactic processes in Dhimal. The overt coding properties of grammatical relations include nominal morphology and verb agreement in Dhimal. The nominal morphology as coding property presents a consistent nominative pattern of control in Dhimal. The pronominal verb agreement and number agreement also follow the nominative pattern. The Equi-NP deletion (or the co-referent deletion) in complement clauses displays the nominative control in the language.
Nepali Verbs: Some Properties
Authors: Prasain Balaram
Published: December 2022

Nepali verb stems end with i, a, o and ʌ vowels, and voiced and voiceless consonants. From transitivity perspective, they are intransitive and transitive/ditransitive. The verbs are monosyllabic and polysyllabic from syllabicity point of view. Another feature that Nepali verbs have is sound [a] whose presence and absence has direct impact on causative stem formation. The causative stem formation is regular with some phonological restrictions; however, the passive stem formation is very productive. Negativization occurs from both prefixation and suffixation processes. On the basis of features and morphological processes, four types of stems, namely, base stem, passive stem, causative stem and causative passive stem are found.
The Kirati Ritual Language: Evidence from Chhintang and Chhulung
Authors: Rai Ichchha Purna
Published: December 2022

This paper deals with the languages used in the rituals practised in Chhintang and Chhulung speech communities. Kirati people have their own culture guided by the mundum. There are four ethnic groups with more than 26 different languages. They have their own separate ritual practices and ritual language. Chhintang and Chhulung have a distinct type of ritual language which is spoken to perform any kind of ritual performances. It has a lot of archaic types of nouns which would be interesting for morpho-semantic analysis. Specially, binomials are unique properties of the ritual language and too complex structurally.
Some Sociolinguistic and Morphosyntactic Features in Dumi
Authors: Rai Netra Mani
Published: December 2022

Dumi is a less described Kirati language of the Rai group. The word order phenomenon in this language is of SOV pattern. This language exhibits a consistently ergative-absolutive case marking system. Including the glottal stop, there are 26 consonants and seven phonemic vowels in Dumi. The maximum syllable structure is (C1) (C2) (G) V (X), where G is a glide and ‘X’ is a consonant or a vowel. Dumi children are compelled to read and write in Nepali or English. However, the Dumi language will survive if the Dumi people continue to speak, read and write in their mother tongue.
Structural Properties of Nouns in Western Tamang
Authors: Regmi Ambikja
Published: December 2022

Western Tamang (WT), a major dialect of Tamang, exhibits typologically interesting structural properties in the domain of nouns in contrast to Eastern Tamang (ET). Like in ET, the common nouns in WT are marked for gender, number, classifier and relational functions by specific markers. Unlike Himalayish languages and like ET and other Bodish languages, WT does not exhibit agreement between the subject and the verb in terms of gender and number. However, WT differs from ET, especially, in the domains of number, case markings and case syncretism.
Understanding Ethnic and Cultural Diversity: Evidence from Puma
Authors: Sharma Narayan P.
Published: December 2022

The most significant and most obvious factor behind the growth of ethnic and cultural diversity in Nepal, is of course, the country’s multilingual context. Multicultural context, in turn, reflects the cultural and linguistic diversity, and social thinking of the period during which the context came into existence. We can argue that cultural and ethnic diversity has always been a source of strength and unity in Nepali society. This article addresses the ethnic and cultural diversity of the Puma people. The future of Nepal will be even more ethnically and culturally diverse than it is today.
नेपालमा भाषाहरुको स्थिति र भाषिक सर्वेक्षण : समीक्षlत्मक विश्लेषण {Status of Languages ​​and Linguistic Survey in Nepal: A Critical Analysis}
Authors: रेग्मी Regmi दानराज Danraj
Published: December 2022

Available with fulltext.
Intraoperative Optical Coherence Tomography –Available Technologies and Possibilities of Use. A Review
Authors: Benda Tomáš , Studený Pavel
Published: December 2022

Optical coherence tomography (OCT) is a non-contact and non-invasive imaging and diagnostic method, that allows the imaging of ocular tissues on transverse sections in extremely high quality of micrometer resolution. The physical principle of OCT is analogous to ultrasound, but it uses infrared radiation instead of acoustic waves. By using a low coherent radiation source, it is possible to achieve a higher resolution. Based on the obtained data, the computer can reconstruct two or three-dimensional images of the examined tissue. In recent years, we have seen a rapid development in ophthalmic surgery, especially in surgical instruments and imaging methods. However, the technology of surgical microscopes does not change significantly and thus becomes a limiting factor in the development of ophthalmic microsurgery. The integration of the OCT into surgical microscopes, so the introduction of the Intraoperative Optical Coherence Tomography (iOCT), opens up further possibilities for displaying/looking at the operating field and adapting surgical techniques to the current situation during the surgery. On the contrary, the disadvantage is the prolongation of the surgery time and thus the theoretical increase in possible complications related to the surgery. iOCT can be used for operations on the anterior and posterior segment of the eye. In anterior segment surgery, it is used mostly in penetrating and lamellar keratoplasty, glaucoma surgery and cataract surgery. In posterior segment surgery, it is used during pars plana vitrectomy. The aim of the article is to provide a comprehensive overview of the current possibilities of using iOCT in eye surgery.
En Bloc Resection of Retinal Vasoproliferative Tumor Using 23g Vitrectomy. A Case Report
Authors: Forgáč František , Sekerešová Monika , Černák Martin
Published: December 2022

Purpose: Retinal vasoproliferative tumor is one of the benign vascular tumors which in advanced stages leads to exudative retinal detachment with the formation of epiretinal and subretinal membranes. In such advanced stages, one of the therapeutic options is pars plana vitrectomy. This article presents the case of a patient on whom was performed 23-gauge pars plana phacovitrectomy with en bloc resection of the tumor followed by histological confirmation.
Case report: A 70-year-old patient with a one-year history of unilateral loss of vision in his left eye was admitted to our clinic for examination in February 2018. At admission, the best corrected visual acuity in the right eye was 1.0, and in the left eye was light perception. Based on the clinical picture, sonographic examination of the eye, and fluorescein angiography, the patient was diagnosed with a retinal vasoproliferative tumor. Due to the advanced stage of disease, we proceeded with surgical intervention. We performed 23-gauge phacovitrectomy with a bloc resection of the tumor. Subsequent histological examination confirmed the presence of the presumed tumor. The follow-up exam a few months later showed a completely attached retina with silicone oil tamponade, without exudative retinopathy. However, the best corrected visual acuity improved only slightly to the ability to count fingers at one meter.
Conclusion: Pars plana vitrectomy with en bloc resection of retinal vasoproliferative tumor is one of the therapeutic modalities in advanced stages.
Chelation of Band Keratopathy in Long-Term Observation
Authors: Kristian Petr , Cholevík Daniel
Published: December 2022

Aim: To report the clinical results of chelation of band keratopathy in long-term follow-up.
Material and methods: The long-term results of 5 patients (5 eyes) with symptomatic band keratopathy with a follow-up period of at least 6 months, in whom 2% EDTA was chelated on the affected eye in the study period from April 2018 to March 2021, were retrospectively evaluated. The follow-up period was 9-37 months.
Results: In all patients, there was a significant improvement in the local findings and an increase in the transparency of the cornea. The effect of therapy was verified on a color photograph of the anterior segment and on AS-OCT by the disappearance of subepithelial hyperreflective foci and accompanying optical shadows. Postoperatively, this enabled a more detailed visualization of the deeper layers of the cornea and other structures of the anterior segment. In a patient with the potential to improve vision, it was also possible to significantly improve visual functions. In the other three patients with pain in the affected eye, the pain subsided, and they also benefited cosmetically from the operation.
Conclusion: Based on our experience and previously published reports, EDTA corneal chelation is able to causally resolve the pathology and improve vision in eyes with visual potential. At the same time, it reduces discomfort and has an analgesic effect in long-term irritated eyes. The operation is also suitable for amaurotic, cosmetically unsightly bulbs, as a successful intervention preserving the eye and improving the appearance of such eyes leads to satisfaction and a subjective increase in the quality of life of the patients.
Tubulointerstitial Nephritis With Uveitis (Tinu Syndrome). A Case Report
Authors: Kurašová Ester , Orság Jiří , Klementa Viktor , Krejčí Karel
Published: December 2022

In this case report, we describe the case of a 50-year-old woman referred by her general practitioner to a pulmonologist in order to investigate persistent fever and elevation of C-reactive protein despite antibiotic treatment following a respiratory infection. The patient was examined extensively, during which rheumatology, gastroenterology, nephrology, ophthalmology, laboratory and imaging tests were performed. Due to a rapid progression of renal insufficiency with active urinary sediment, the patient was referred for a renal biopsy, which confirmed tubulointerstitial nephritis, followed by a diagnosis of bilateral anterior uveitis two months later - genetic testing was also conducted, which confirmed the diagnosis of tubulointerstitial nephritis with uveitis syndrome. Steroid treatment brought about a gradual reduction of proteinuria and a stabilisation of renal function.