bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review on Chitosan’s Uses as Biomaterial: Tissue Engineering, Drug Delivery Systems and Cancer Treatment
Authors: de Sousa Victor Rayssa , Marcelo da Cunha Santos Adillys , Viana de Sousa Bianca , de Araújo Neves Gelmires , Navarro de Lima Santana Lisiane , Rodrigues Menezes Romualdo
Published: November 2020

Chitosan, derived from chitin, is a biopolymer consisting of arbitrarily distributed β-(1-4)-linked D-glucosamine and N-acetyl-D-glucosamine that exhibits outstanding properties— biocompatibility, biodegradability, non-toxicity, antibacterial activity, the capacity to form films, and chelating of metal ions. Most of these peculiar properties are attributed to the presence of free protonable amino groups along the chitosan backbone, which also gives it solubility in acidic conditions. Moreover, this biopolymer can also be physically modified, thereby presenting a variety of forms to be developed. Consequently, this polysaccharide is used in various fields, such as tissue engineering, drug delivery systems, and cancer treatment. In this sense, this review aims to gather the state-of-the-art concerning this polysaccharide when used as a biomaterial, providing information about its characteristics, chemical modifications, and applications. We present the most relevant and new information about this polysaccharide-based biomaterial’s applications in distinct fields and also the ability of chitosan and its various derivatives to selectively permeate through the cancer cell membranes and exhibit anticancer activity, and the possibility of adding several therapeutic metal ions as a strategy to improve the therapeutic potential of this polymer.
Effect of Calcium Acetate Content on Apatite-Forming Ability and Mechanical Property of PMMA Bone Cement Modified with Quaternary Ammonium
Authors: Wang Haiyang , Maeda Toshinari , Miyazaki Toshiki
Published: November 2020

Polymethyl methacrylate (PMMA)-based bone cement is a popular biomaterial used for fixation of artificial joints. A next-generation bone cement having bone-bonding ability, i.e., bioactivity and antibacterial property is desired. We previously revealed that PMMA cement added with 2-(tert-butylamino)ethyl methacrylate, γ-methacryloxypropyltrimethoxysilane and calcium acetate showed in vitro bioactivity and antibacterial activity. This cement contains calcium acetate at 20% of the powder component. Lower content of the calcium acetate is preferable, because the release of a lot of calcium salt may degrade mechanical properties in the body environment. In the present study, we investigate the effects of calcium acetate content on the setting property and mechanical strength of the cement and apatite formation in simulated body fluid (SBF). The setting time increased and the compressive strength decreased with an increase in calcium acetate content. Although the compressive strength decreased after immersion in SBF for 7 d, all the cements still satisfied the requirements of ISO5833. Apatite was formed in SBF within 7 d on the samples where the calcium acetate content was 5% or more. Therefore, it was found that PMMA cement having antibacterial properties and bioactivity can be obtained even if the amount of the calcium acetate is reduced to 5%.
Difference in Strength Development between Cement-Treated Sand and Mortar with Various Cement Types and Curing Temperatures
Authors: Ho Lanh Si , Nakarai Kenichiro , Eguchi Kenta , Ogawa Yuko
Published: November 2020

To improve the strength of cement-treated sand effectively, the use of various cement types was investigated at different curing temperatures and compared with the results obtained from similar mortars at higher cement contents. The compressive strengths of cement-treated sand specimens that contained high early-strength Portland cement (HPC) cured at elevated and normal temperatures were found to be higher than those of specimens that contained ordinary Portland cement (OPC) and moderate heat Portland cement at both early and later ages. At 3 days, the compressive strength of the HPC-treated sand specimen, normalized with respect to that of the OPC under normal conditions, is nearly twice the corresponding value for the HPC mortar specimens with water-to-cement ratio of 50%. At 28 days, the normalized value for HPC-treated sand is approximately 1.5 times higher than that of mortar, with a value of 50%. This indicates that the use of HPC contributed more to the strength development of the cement-treated sand than to that of the mortar, and the effects of HPC at an early age were higher than those at a later age. These trends were explained by the larger quantity of chemically bound water observed in the specimens that contained HPC, as a result of their greater alite contents and porosities, in cement-treated sand. The findings of this study can be used to ensure the desired strength development of cement-treated soils by considering both the curing temperature and cement type. Furthermore, they suggested a novel method for producing a high internal temperature for promoting the strength development of cement-treated soils.
Study of Cement-Based Superhydrophobic Composite Coating: New Option for Water Drainage Pipeline Rehabilitation
Authors: Wang Tianyu , Zeng Cong
Published: November 2020

A great number of urban underground concrete water drainage systems in China are facing challenges of corrosion, blockage, and leakage. This could result in engineering accidents such as urban inland inundation, pipeline collapse, leakage, and blockage. The common contributing factors for pipeline leakage and blockage are the porous structures and the perishable surfaces of concrete pipes. To address these issues, we synthesized superhydrophobic coating materials such as SiO2 aerosol, bisphenol A diglycidyl ether (DGEBA), and N-β-aminoethyl-γ-aminopropyltrimethoxysilane (AEAPTS). Our superhydrophobic coating on cement-based surfaces presents good waterproof ability, mechanical stability, and self-cleaning properties. Test results show that the superhydrophobic coating exhibits higher water discharge capacity and survivability to corrosive underground water drainage pipeline environments. Hence, this SiO2 aerosol @ bisphenol A diglycidyl ether coating possesses enormous potential in surface modification of pipeline rehabilitation materials.
Creating Strong Titanium/Titanium Hydride Brown Bodies at Ambient Pressure and Moderate Temperatures
Authors: Phillips Jonathan , Janssen Anthony , Y. Ansell Troy , C. Luhrs Claudia
Published: November 2020

A simple, low temperature, method, hydrogen-enhanced atomic transport (HEAT), for creating metallic-bonded brown bodies of order 40% bulk density in molds of designed shape from Ti metal particles is introduced. In this initial study 40 micron titanium particles were poured into graphite molds, then heated to temperatures equal to or greater than 650 °C for four hours in a flowing ambient pressure gas mixture containing some hydrogen led to brown body formation that closely mimicked the mold shape. The brown bodies were shown to be dense, metallic bonded, and consisted of primarily Ti metal, but also some TiH. It is postulated that hydrogen is key to the sintering mechanism: it enables the formation of short-lived TiHx species, volatile at the temperatures employed, that lead to sintering via an Ostwald Ripening mechanism. Data consistent with this postulate include findings that brown bodies are formed with hydrogen present (HEAT process) had mechanical robustness and only suffered plastic deformation at high pressure (ca. 5000 Atm). In contrast, brown bodies made in identical conditions, except the flowing gas did not contain hydrogen, were brittle, and broke into micron scale particles under much lower pressure. HEAT appears to have advantages relative to existing titanium metal part manufacturing methods such as powder injection molding that require many more steps, particularly debinding, and other methods, such as laser sintering, that are slower, require very expensive hardware and expert operation.
A Fuzzy Graph Based Chemometrics Method for Gelatin Authentication
Authors: Hassan Nurfarhana , Ahmad Tahir , Zain Norhidayu M. , Awang Siti Rahmah
Published: November 2020

Graph theory is a well-established concept that is widely used in numerous applications such as in biology, chemistry and network analysis. The advancement in the theory of graph has led to the development of a new concept called fuzzy autocatalytic set. In this paper, a fuzzy graph-based chemometrics method, namely, chemometrics fuzzy autocatalytic set (c-FACS) is developed and applied for gelatin authentication. The issue on authenticity of gelatin has become a sensitive issue among some religious communities. Due to the matter, Fourier transform infrared (FTIR) spectra of bovine, porcine and fish gelatins are analyzed using c-FACS to identify their signatures and differences and presented in this paper. The results from the c-FACS analysis showed distinct features of each gelatin, particularly porcine. Furthermore, the new method is faster than principal component analysis (PCA) in identifying the gelatin sources.
Cryptocurrencies as a Financial Tool: Acceptance Factors
Authors: Gil-Cordero Eloy , Cabrera-Sánchez Juan Pedro , Arrás-Cortés Manuel Jesús
Published: November 2020

Cryptocurrencies are a new form of digital asset that operate through blockchain technology and whose purpose is to be used as a means of exchange. Some, such as bitcoin, have become globally recognized in recent years, but the uncertainty surrounding cryptocurrencies raises questions about their intended use. This study has the task of investigating the different factors that affect the intention behind the use of cryptocurrencies by developing a new research model and using Partial Least Squares (PLS) to assess it. The results show that all the constructs proposed have significative influence, either directly or indirectly, on the intention behind the use of cryptocurrencies. The findings provide value and utility for companies’ and cryptocurrencies’ intermediaries to formulate their business strategies.
The Optimal Control of Government Stabilization Funds
Authors: Cadenillas Abel , Huamán-Aguilar Ricardo
Published: November 2020

We study the optimal control of a government stabilization fund, which is a mechanism to save money during good economic times to be used in bad economic times. The objective of the fund manager is to keep the fund as close as possible to a predetermined target. Accordingly, we consider a running cost associated with the difference between the actual fiscal fund and the fund target. The fund manager exerts control over the fund by making deposits in or withdrawals from the fund. The withdrawals are used to pay public debt or to finance government programs. We obtain, for the first time in the literature, the optimal band for the government stabilization fund. Our results are of interest to practitioners. For instance, we find that the higher the volatility, the larger the size of the optimal band. In particular, each country and state should have its own optimal fund band, in contrast to the “one-size-fits-all” approach that is often used in practice.
Kurilosides A1, A2, C1, D, E and F—Triterpene Glycosides from the Far Eastern Sea Cucumber Thyonidium (= Duasmodactyla) kurilensis (Levin): Structures with Unusual Non-Holostane Aglycones and Cytotoxicities
Authors: Silchenko Alexandra S. , Kalinovsky Anatoly I. , Avilov Sergey A. , Andrijaschenko Pelageya V. , Popov Roman S. , Dmitrenok Pavel S. , Chingizova Ekaterina A. , Kalinin Vladimir I.
Published: November 2020

Six new monosulfated triterpene tetra-, penta- and hexaosides, namely, the kurilosides A1 (1), A2 (2), C1 (3), D (4), E (5) and F (6), as well as the known earlier kuriloside A (7), having unusual non-holostane aglycones without lactone, have been isolated from the sea cucumber Thyonidium (= Duasmodactyla) kurilensis (Levin) (Cucumariidae, Dendrochirotida), collected in the Sea of Okhotsk near Onekotan Island from a depth of 100 m. Structures of the glycosides were established by 2D NMR spectroscopy and HR-ESI mass spectrometry. Kurilosides of the groups A and E contain carbohydrate moieties with a rare architecture (a pentasaccharide branched by C(4) Xyl1), differing from each other in the second monosaccharide residue (quinovose or glucose, correspondingly); kurilosides of the group C are characterized by a unique tetrasaccharide branched by a C(4) Xyl1 sugar chain; and kurilosides of the groups D and F are hexaosides differing from each other in the presence of an O-methyl group in the fourth (terminal) sugar unit. All these glycosides contain a sulfate group at C-6 of the glucose residue attached to C-4 Xyl1 and the non-holostane aglycones have a 9(11) double bond and lack γ-lactone. The cytotoxic activities of compounds 1–7 against mouse neuroblastoma Neuro 2a, normal epithelial JB-6 cells and erythrocytes were studied. Kuriloside A1 (1) was the most active compound in the series, demonstrating strong cytotoxicity against the erythrocytes and JB-6 cells and a moderate effect against Neuro 2a cells.
Quasi-3D Hyperbolic Shear Deformation Theory for the Free Vibration Study of Honeycomb Microplates with Graphene Nanoplatelets-Reinforced Epoxy Skins
Authors: Arshid Hossein , Khorasani Mohammad , Soleimani-Javid Zeinab , Dimitri Rossana , Tornabene Francesco
Published: November 2020

A novel quasi-3D hyperbolic shear deformation theory (QHSDT) with five unknowns is here employed, together with the Hamilton’s principle and the modified couple stress theory (MCST) to analyze the vibrational behavior of rectangular micro-scale sandwich plates resting on a visco-Pasternak foundation. The sandwich structure features a Nomex or Glass phenolic honeycomb core, and two composite face sheets reinforced with graphene nanoplatelets (GPLs). The effective properties of both face sheets are evaluated by means of the Halpin-Tsai and extended rule of mixture (ERM) micromechanical schemes. The governing equations of the problem are derived by applying the Hamilton’s principle, whose solutions are determined theoretically according to a classical Navier-type procedure. A parametric study checks for the effect of different material properties, length-scale parameters, foundation parameters and geometrical properties of the honeycomb cells, and the reinforcing GPLs, on the vibration response of the layered structure, which can be of great interest for many modern engineering applications and their optimization design.
Non-Linear Optical Property and Biological Assays of Therapeutic Potentials Under In Vitro Conditions of Pd(II), Ag(I) and Cu(II) Complexes of 5-Diethyl amino-2-({2-[(2-hydroxy-Benzylidene)-amino]-phenylimino}-methyl)-phenol
Authors: Abdel-Rahman Laila H. , Adam Mohamed S. , Abu-Dief Ahmed M. , Ahmed Hanan El-Sayed , Nafady Ayman
Published: November 2020

Herein, we report facile procedures for synthesis of a new Schiff base ligand (H2L,5-Diethylamino-2-({2-[(2-hydroxy-benzylidene)-amino]-phenylimino}-methyl)-phenol) and its Ag(I), Pd(II) and Cu(II) complexes. The structure of the H2L ligand as well as its metal complexes was deduced based on wide range of analytical, structural and spectroscopic tools, along with theoretical evidence via density functional theory (DFT) calculations. The obtained results indicated that the Schiff base (H2L) ligand acts as a tetradentate N2O2 donor with two azomethine nitrogen’s (N1, N2) and two deprotonated phenolic oxygens (O1, O2) atoms. A distorted octahedral structure is assigned to [CuL(OH2)2]·3/2H2O complex and square planar structure for PdL and AgL complexes. The electronic structure and non-linear optical (NLO) property of the prepared compounds were discussed theoretically by the B3LYP/GENECP program. Results revealed that all complexes have non-planner geometries as indicated from the dihedral angles. The charge transfer occurs within the synthesized complexes as indicated from the calculated energy gap between HOMO and LUMO energies. The H2L ligand and its complexes are excellent candidates for NLO materials as implied from their hyperpolarizabilities and polarizabilities values. The biological activities of the prepared complexes against selected microorganisms and cancer cell lines gave good growth inhibitory effect. The biocidal potencies of the ligand and its complexes can be arranged as follows: AgL > CuL > PdL > H2L, as compared to the used standard drugs. The antiproliferative activity of the studied complexes against different carcinoma cell lines such as liver (Hep-G2), breast (MCF-7) and colon (HCT-116) followed the order H2L < AgL< PdL < CuL < vinblastine. Probing the binding interactions of prepared complexes with calf thymus (CT)-DNA using electronic absorption, gel electrophoresis and viscosity measurements revealed strong interaction via intercalation modes, as also evidenced by their molecular docking study.
Development of Diphenethylamines as Selective Kappa Opioid Receptor Ligands and Their Pharmacological Activities
Authors: Schmidhammer Helmut , Erli Filippo , Guerrieri Elena , Spetea Mariana
Published: November 2020

Among the opioid receptors, the kappa opioid receptor (KOR) has been gaining substantial attention as a promising molecular target for the treatment of numerous human disorders, including pain, pruritus, affective disorders (i.e., depression and anxiety), drug addiction, and neurological diseases (i.e., epilepsy). Particularly, the knowledge that activation of the KOR, opposite to the mu opioid receptor (MOR), does not produce euphoria or leads to respiratory depression or overdose, has stimulated the interest in discovering ligands targeting the KOR as novel pharmacotherapeutics. However, the KOR mediates the negative side effects of dysphoria/aversion, sedation, and psychotomimesis, with the therapeutic promise of biased agonism (i.e., selective activation of beneficial over deleterious signaling pathways) for designing safer KOR therapeutics without the liabilities of conventional KOR agonists. In this review, the development of new KOR ligands from the class of diphenethylamines is presented. Specifically, we describe the design strategies, synthesis, and pharmacological activities of differently substituted diphenethylamines, where structure–activity relationships have been extensively studied. Ligands with distinct profiles as potent and selective agonists, G protein-biased agonists, and selective antagonists, and their potential use as therapeutic agents (i.e., pain treatment) and research tools are described.
Highly Conductive PEDOT:PSS Thin Films with Two-Dimensional Lamellar Stacked Multi-Layers
Authors: Kim Youngno , Kim Yunryeol , Kim Jung
Published: November 2020

Conjugated polymers are desired as organic electrode materials because of their functional properties such as solution process, low cost, and transparency. Poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), in particular, shows the highest applicability, but its heterogeneous structure presents limitations in terms of electrical conductivity. In this study, a facile method to fabricate multi-layered thin films with higher ordered structures was developed. Through the etching process with H2SO4 and dimethyl sulfoxide(DMSO), the insulated rich-PSS was removed from the upper layer to improve its electrical properties and rearrange the PEDOT molecular structures. The thickness of PEDOT:PSS thin films was experimentally optimized to maximize the enhancement of carrier mobility via a layer-by-layer (LBL) process. The combined method, consisted of etching and the LBL process, showed the improvement of the charge carrier mobility from 0.62 to 2.80 cm2 V−1 s−1. The morphology and crystallinity of the ordered PEDOT:PSS structure were investigated by X-ray photoemission spectroscopy (XPS), Raman, and X-ray diffraction (XRD). As a result, two-dimensional lamellar-stacked PEDOT:PSS thin films were fabricated through the repetitive etching and LBL process. The optimized PEDOT:PSS thin film showed an excellent electrical conductivity of 3026 S cm−1, which is 3.8 times higher than that of the pristine film (801 S cm−1).
Exercise and/or Genistein Treatment Impact Gut Microbiota and Inflammation after 12 Weeks on a High-Fat, High-Sugar Diet in C57BL/6 Mice
Authors: Ortega-Santos Carmen P. , Al-Nakkash Layla , Whisner Corrie M.
Published: November 2020

Genistein (Gen) and exercise (Exe) have been postulated as potential strategies to ameliorate obesity, inflammation, and gut microbiota (GM) with promising results. However, the impact of the combination of both Exe and Gen is yet to be investigated. We aimed to analyze the impacts of Exe, Gen, and their combined effects on GM and inflammation in mice after a 12-week high-fat, high-sugar diet (HFD). Eighty-three C57BL/6 mice were randomized to control, HFD, HFD + Exe, HFD + Gen, or HFD + Exe + Gen. The V4 region of the 16S rRNA gene was analyzed with Illumina MiSeq. Serum samples were used to analyze interleukin (Il)-6 and Tumor Necrosis Factor alpha (TNF-alpha). The HFD + Exe and HFD + Exe + Gen treatments resulted in significantly greater microbial richness compared to HFD. All the treatments had a significantly different impact on the GM community structure. Ruminococcus was significantly more abundant after the HFD + Exe + Gen treatment when compared to all the other HFD groups. Exe + Gen resulted in serum Il-6 concentrations similar to that of controls. TNF-alpha concentrations did not differ by treatment. Overall, Exe had a positive impact on microbial richness, and Ruminococcus might be the driving bacteria for the GM structure differences. Exe + Gen may be an effective treatment for preventing HFD-induced inflammation.
Application of High-Performance Liquid Chromatography for Simultaneous Determination of Tenofovir and Creatinine in Human Urine and Plasma Samples
Authors: Olejarz Patrycja , Chwatko Grażyna , Kubalczyk Paweł , Purgat Krystian , Głowacki Rafał , Borowczyk Kamila
Published: November 2020

Tenofovir disoproxil fumarate is widely used in the therapy of human immunodeficiency virus and hepatitis B virus; however, a high concentration of the prodrug effects kidney function damage. To control the effectiveness of kidney functions in treated patients, the level of creatinine in the body must be controlled. This work describes a simple, fast, and “plastic-waste” reducing method for the simultaneous determination of tenofovir and creatinine in human urine and plasma. In both assays, only 50 µL of body fluid was required. The tests were carried out by reversed phase high-performance liquid chromatography with UV detection. In urine samples, the limits of detection for tenofovir and creatinine were 4 µg mL−1 and 0.03 µmol mL−1, respectively. In plasma samples, the limits of detection were 0.15 µg mL−1 for tenofovir and 0.0003 µmol mL−1 for creatinine. The method was applied for the determination of tenofovir and creatinine in human urine and plasma samples. The biggest advantage of the elaborated method is the possibility to determine tenofovir and creatinine in one analytical run in both urine and plasma sample collected from HIV and HBV patients. The possibility to reduce the level of laboratory waste in a sample preparation protocol is in the mainstream of a new trend of analytical chemistry which is based on green chemistry.
Biofilm Inhibition and Eradication Properties of Medicinal Plant Essential Oils against Methicillin-Resistant Staphylococcus aureus Clinical Isolates
Authors: Ben Abdallah Fethi , Lagha Rihab , Gaber Ahmed
Published: November 2020

Methicillin-resistant Staphylococcus aureus is a major human pathogen that poses a high risk to patients due to the development of biofilm. Biofilms, are complex biological systems difficult to treat by conventional antibiotic therapy, which contributes to >80% of humans infections. In this report, we examined the antibacterial activity of Origanum majorana, Rosmarinus officinalis, and Thymus zygis medicinal plant essential oils against MRSA clinical isolates using disc diffusion and MIC methods. Moreover, biofilm inhibition and eradication activities of oils were evaluated by crystal violet. Gas chromatography–mass spectrometry analysis revealed variations between oils in terms of component numbers in addition to their percentages. Antibacterial activity testing showed a strong effect of these oils against MRSA isolates, and T. zygis had the highest activity succeeded by O. majorana and R. officinalis. Investigated oils demonstrated high biofilm inhibition and eradication actions, with the percentage of inhibition ranging from 10.20 to 95.91%, and the percentage of eradication ranging from 12.65 to 98.01%. O. majorana oil had the highest biofilm inhibition and eradication activities. Accordingly, oils revealed powerful antibacterial and antibiofilm activities against MRSA isolates and could be a good alternative for antibiotics substitution.
To Send a Kite: Simone Weil’s Lessons in Ethical Attention for the Curator
Authors: Sava Maggie
Published: November 2020

As socially engaged practices grow within the curatorial field, the use of attention becomes a crucial ethical decision. How and to whom attention is given centers on concerns of visibility, belonging, and the determination of those characteristics within a community’s negotiated communicative space. Exploring Simone Weil’s ethics of attention through and alongside incarceration-focused curatorial projects, this article positions her writing as a potential framework for attentive curation. The resulting pathways found in Weil’s writing offer means of transforming the curatorial into a self-silencing act of witnessing that serves underrecognized voices. This research parses how Weilian attention redefines inquiry as the process of listening to and incorporating others’ perspectives as primary sources of knowledge. Looking towards an ethics of Weilian attention with examples of incarceration-focused curation reveals how upholding the insights and articulations of marginalized individuals promotes social wellbeing and works towards the realization of justice. Thousand Kites, a prison-based project connecting inmates and the public through the radio and internet, provides the central case study for a curatorial project aligning with Weilian attention.
Evolution from Periodic Intensity Modulations to Dissipative Vector Solitons in A Single-Mode Fiber Laser
Authors: Hu Xiao , Guo Jun , Li Lei , Yoo Seongwoo , Tang Dingyuan
Published: November 2020

We investigated—both experimentally and numerically—the operation of a weakly birefringent cavity fiber laser under different net cavity dispersion values. Experimentally, we found that under coherent cross-polarization coupling, either in-phase or anti-phase low frequency intensity modulations between the two orthogonal polarization components of the laser emission could be obtained. The evolution of the periodic intensity modulations in the fiber laser under different operation conditions was studied. In this paper, we show that under suitable conditions, they can be shaped into a train of bright-bright, dark-dark, or dark-bright vector solitons.
Effect of Lignin Content on Properties of Flexible Transparent Poplar Veneer Fabricated by Impregnation with Epoxy Resin
Authors: Lu Mengting , He Wen , Li Ze , Qiang Han , Cao Jizhou , Guo Feiyu , Wang Rui , Guo Zhihao
Published: November 2020

In this work, poplar veneer (PV) rotary-cut from fast-growing polar was delignified to prepare flexible transparent poplar veneer (TPV). Lignin was gradually removed from the PV and then epoxy resin filled into the delignified PV. The study mainly concerns the effect of lignin content on microstructure, light transmittance, haze, tensile strength, and thermal stability of the PVs impregnated with epoxy resin. The results indicate that the lignin could be removed completely from the PV when the delignification time was around 8 h, which was proved by FTIR spectra and chemical component detection. Moreover, according to SEM observation and XRD testing, the porosity and crystallinity of the PVs were gradually increased with the removal of lignin. Also, the optical properties measurement indicated that the light transmittance and haze of the TPVs gradually increased, and the thermal stability also became more stable as shown by thermogravimetric analysis (TG). However, the tensile strength of the TPVs declined due to the removal of lignin. Among them, TPV8 exhibited excellent optical properties, thermal stability, and tensile strength. Consequently, it has great potential to be used as a substrate in photovoltaics, solar cells, smart windows, etc.
The Effects of Silver Nanoparticles Compositions on the Mechanical, Physiochemical, Antibacterial, and Morphology Properties of Sugar Palm Starch Biocomposites for Antibacterial Coating
Authors: Rozilah A. , Jaafar C. N. Aiza , Sapuan S. M. , Zainol I. , Ilyas R. A.
Published: November 2020

Antibacterial sugar palm starch biopolymer composite films were developed and derived from renewable sources and inorganic silver nanoparticles (AgNPs) as main ingredients for antibacterial coatings. The composite films were produced by solution casting method and the mechanical and physicochemical properties were determined by tensile test, Fourier Transform Infrared (FTIR) analysis, thermal gravimetric analysis (TGA), antibacterial screening test and field emission scanning electron microscopy (FESEM) images. It was found that mechanical and antibacterial properties of biocomposite films were improved after the addition of AgNPs compared with the film without active metals. The weakness of neat biocomposite films was improved by incorporating inorganic AgNPs as a nanofiller in the films’ matrix to avoid bacterial growth. The results showed that the tensile strength ranged between 8 kPa and 408 kPa and the elasticity modulus was between 5.72 kPa and 9.86 kPa. The addition of AgNPs in FTIR analysis decreased the transmittance value, caused small changes in the chemical structure, caused small differences in the intensity peaks, and produced longer wavelengths. These active films increased the degradation weight and decomposition temperature due to the more heat-stable AgNPs. Meanwhile, the average inhibited areas measured were between 7.66 and 7.83 mm (Escherichia coli), 7.5 and 8.0 mm (Salmonella cholerasuis), and 0.1 and 0.5 mm for Staphylococcus aureus. From the microscopic analysis, it was observed that the average size of all microbes for 1 wt% and 4 wt% AgNPs ranged from 0.57 to 2.90 mm. Overall, 3 wt% AgNP nanofiller was found to be the best composition that fulfilled all the mechanical properties and had better antimicrobial properties. Thus, the development of an organic-inorganic hybrid of antibacterial biopolymer composite films is suitable for antibacterial coatings.
Building Skills for the Future: Teaching High School Students to Utilize Remote Sensing of Wildfires
Authors: Amici Stefania , Tesar Marek
Published: November 2020

A substantial proportion of Italian students are unaware of the connection between what they learn at school and their work opportunities .This proportion would most likely increase if data were collected today, given the generation of a broad range of new jobs that has arisen due to advancements in technology. This gap between students’ understanding of what they learn at school and its application to the broader world—the society, the economy and the political sphere—suggests there needs to be a rethinking of how teaching and learning at school is conceived and positioned. To help students to approach ongoing social and economic transformations, the Italian Educational Ministry (MIUR) has endorsed a school–work interchange program which, aligned with the principle of open schools, aims to provide students with work experience. It is within the scope of this initiative that we have tested high school students with remote sensing (RS) from space projects. The experience-based approach aimed to verify students’ openness to the use of satellite data as a means to learn new interdisciplinary skills, to familiarize themselves with methodological knowledge and, finally, to inspire them when choosing a university or areas of future work. We engaged three cohorts, from 2017, 2018 and 2019, for a total of 40 h each year, including contact and non-contact time. The framework of each project was the same for the three cohorts and focused on the observation of Earth from space with a specific focus on wildfires. However, the initiative went beyond this, with diverse activities and tasks being assigned. This paper reports the pedagogical methods utilized with the three cohorts and how these methods were transformed and adapted in order to improve and enhance the learning outcomes. It also explores the outcomes for the students, teachers and family members, with respect to their learning and general appreciation.
New Higher-Order Correction of GNSS RO Bending Angles Accounting for Ionospheric Asymmetry: Evaluation of Performance and Added Value
Authors: Liu Congliang , Kirchengast Gottfried , Syndergaard Stig , Schwaerz Marc , Danzer Julia , Sun Yueqiang
Published: November 2020

The residual ionospheric error (RIE) from higher-order terms in the refractive index is not negligible when using global navigation satellite system (GNSS) radio occultation (RO) data for climate and meteorology applications in the stratosphere. In this study, a new higher-order bending angle RIE correction named “Bi-local correction approach” has been implemented and evaluated, which accounts for the ray path splitting of the dual-frequency GNSS signals, the altitude of the low Earth orbit (LEO) satellite, the ionospheric inbound (GNSS to tangent point) vs. outbound (tangent point to LEO) asymmetry, and the geomagnetic field. Statistical results based on test-day ensembles of RO events show that, over the upper stratosphere and mesosphere, the order of magnitude of the mean total RIE in the bi-local correction approach is 0.01 μrad. Related to this, the so-called electron-density-squared (Ne2) and geomagnetic (BNe) terms appear to be dominant and comparable in magnitude. The BNe term takes negative or positive values, depending on the angle between the geomagnetic field vector and the direction of RO ray paths, while the Ne2 term is generally negative. We evaluated the new approach against the existing “Kappa approach” and the standard linear dual-frequency correction of bending angles and found it to perform well and in many average conditions similar to the simpler Kappa approach. On top of this, the bi-local approach can provide added value for RO missions with low LEO altitudes and for regional-scale applications, where its capacity to account for the ionospheric inbound-outbound asymmetry as well as for the geomagnetic term plays out.
Differences in Motion Accuracy of Baduanjin between Novice and Senior Students on Inertial Sensor Measurement Systems
Authors: Li Hai , Khoo Selina , Yap Hwa Jen
Published: November 2020

This study aimed to evaluate the motion accuracy of novice and senior students in Baduanjin (a traditional Chinese sport) using an inertial sensor measurement system (IMU). Study participants were nine novice students, 11 senior students, and a teacher. The motion data of all participants were measured three times with the IMU. Using the motions of the teacher as the standard motions, we used dynamic time warping to calculate the distances between the motion data of the students and the teacher to evaluate the motion accuracy of the students. The distances between the motion data of the novice students and the teacher were higher than that between senior students and the teacher (p < 0.05 or p < 0.01). These initial results showed that the IMU and the corresponding mathematical methods could effectively distinguish the differences in motion accuracy between novice and senior students of Baduanjin.
Propagation and Attenuation Characteristics of an Ultrasonic Beam in Dissimilar-Metal Welds
Authors: Hwang Young-In , Sung Deokyong , Kim Hak-Joon , Song Sung-Jin , Kim Ki-Bok , Kang Sung-Sik
Published: November 2020

Ultrasonic inspection of welds joining dissimilar metals in nuclear power plants has proven to be a challenge, because the ultrasonic waves are subject to diffraction, distortion, scattering, and noise. These perturbations are due to their interactions with coarse-grained microstructures having anisotropic and heterogeneous metallurgical properties that can promote ultrasonic attenuation. In this paper, to improve the reliability of ultrasonic testing for dissimilar-metal welds (DMWs), ultrasonic beam characteristics for DMWs with a buttering layer were investigated in order to analyze the beam distortion phenomenon caused by inhomogeneous anisotropic properties and coarse grains. Ultrasonic testing was performed on DMW specimens using single ultrasonic transducers to investigate the behavior of the ultrasonic beam in the welds. According to the anisotropic and heterogeneous properties, when passing through the weld and the buttering layer of the DMW, ultrasonic waves were distorted and attenuation was high. In particular, in the case of using angular incidence that passed through the weld and the buttering layer in turn, the received ultrasonic data did not contain accurate internal information. From this, it was verified that internal defects may be detected by transmitting ultrasonic waves in different directions. Finally, the existing limitations on the application of non-destructive ultrasonic testing to dissimilar-metal welds were verified, and a solution to the measurement method was proposed.
A Robust Reactive Static Obstacle Avoidance System for Surface Marine Vehicles
Authors: Guardeño Rafael , López Manuel J. , Sánchez Jesús , González Alberto , Consegliere Agustín
Published: November 2020

This paper is centered on the guidance systems used to increase the autonomy of unmanned surface vehicles (USVs). The new Robust Reactive Static Obstacle Avoidance System (RRSOAS) has been specifically designed for USVs. This algorithm is easily applicable, since previous knowledge of the USV mathematical model and its controllers is not needed. Instead, a new estimated closed-loop model (ECLM) is proposed and used to estimate possible future trajectories. Furthermore, the prediction errors (due to the uncertainty present in the ECLM) are taken into account by modeling the USV’s shape as a time-varying ellipse. Additionally, in order to decrease the computation time, we propose to use a variable prediction horizon and an exponential resolution to discretize the decision space. As environmental model an occupancy probability grid is used, which is updated with the measurements generated by a LIDAR sensor model. Finally, the new RRSOAS is compared with other SOA (static obstacle avoidance) methods. In addition, a robustness study was carried out over a set of random scenarios. The results obtained through numerical simulations indicate that RRSOAS is robust to unknown and congested scenarios in the presence of disturbances, while offering competitive performance with respect to other SOA methods.
Non-Contact Respiration Monitoring and Body Movements Detection for Sleep Using Thermal Imaging
Authors: Jakkaew Prasara , Onoye Takao
Published: November 2020

Monitoring of respiration and body movements during sleep is a part of screening sleep disorders related to health status. Nowadays, thermal-based methods are presented to monitor the sleeping person without any sensors attached to the body to protect privacy. A non-contact respiration monitoring based on thermal videos requires visible facial landmarks like nostril and mouth. The limitation of these techniques is the failure of face detection while sleeping with a fixed camera position. This study presents the non-contact respiration monitoring approach that does not require facial landmark visibility under the natural sleep environment, which implies an uncontrolled sleep posture, darkness, and subjects covered with a blanket. The automatic region of interest (ROI) extraction by temperature detection and breathing motion detection is based on image processing integrated to obtain the respiration signals. A signal processing technique was used to estimate respiration and body movements information from a sequence of thermal video. The proposed approach has been tested on 16 volunteers, for which video recordings were carried out by themselves. The participants were also asked to wear the Go Direct respiratory belt for capturing reference data. The result revealed that our proposed measuring respiratory rate obtains root mean square error (RMSE) of 1.82±0.75 bpm. The advantage of this approach lies in its simplicity and accessibility to serve users who require monitoring the respiration during sleep without direct contact by themselves.
Microwave Bone Imaging: A Preliminary Investigation on Numerical Bone Phantoms for Bone Health Monitoring
Authors: Amin Bilal , Shahzad Atif , O’Halloran Martin , Elahi Muhammad Adnan
Published: November 2020

Microwave tomography (MWT) can be used as an alternative modality for monitoring human bone health. Studies have found a significant dielectric contrast between healthy and diseased human trabecular bones. A set of diverse bone phantoms were developed based on single-pole Debye parameters of osteoporotic and osteoarthritis human trabecular bones. The bone phantoms were designed as a two-layered circular structure, where the outer layer mimics the dielectric properties of the cortical bone and the inner layer mimics the dielectric properties of the trabecular bone. The electromagnetic (EM) inverse scattering problem was solved using a distorted Born iterative method (DBIM). A compressed sensing-based linear inversion approach referred to as iterative method with adaptive thresholding for compressed sensing (IMATCS) has been employed for solving the underdetermined set of linear equations at each DBIM iteration. To overcome the challenges posed by the ill-posedness of the EM inverse scattering problem, the L2-based regularization approach was adopted in the amalgamation of the IMATCS approach. The simulation results showed that osteoporotic and osteoarthritis bones can be differentiated based on the reconstructed dielectric properties even for low values of the signal-to-noise ratio. These results show that the adopted approach can be used to monitor bone health based on the reconstructed dielectric properties.
Exploring the Potential of HySpex Hyperspectral Imagery for Extraction of Copper Content
Authors: Jiang Guo , Zhou Shuguang , Cui Shichao , Chen Tao , Wang Jinlin , Chen Xi , Liao Shibin , Zhou Kefa
Published: November 2020

Detritus geochemical information has been proven through research to be an effective prospecting method in mineral exploration. However, the traditional detritus metal content monitoring methods based on field sampling and laboratory chemical analysis are time-consuming and may not meet the requirements of large-scale metal content monitoring. In this study, we obtained 95 detritus samples and seven HySpex hyperspectral imagery scenes with a spatial resolution of 1 m from Karatag Gobi area, Xinjiang, China, and used partial least squares and wavebands selection methods to explore the usefulness of super-low-altitude HySpex hyperspectral images in estimating detritus feasibility and effectiveness of Cu element content. The results show that: (1) among all the inversion models of transformed spectra, power-logarithm transformation spectrum was the optimal prediction model (coefficient of determination(R2) = 0.586, mean absolute error(MAE) = 21.405); (2) compared to the genetic algorithm (GA) and continuous projection algorithm (SPA), the competitive weighted resampling algorithm (CARS) was the optimal feature band-screening method. The R2 of the inversion model was constructed based on the characteristic bands selected by CARS reaching 0.734, which was higher than that of GA (0.519) and SPA (0.691), and the MAE (19.926) was the lowest. Only 20 bands were used in the model construction, which is lower than that of GA (105) and SPA (42); (3) The power-logarithm transforms, and CARS combined with the model of HySpex hyperspectral images and the Cu content distribution in the study area were obtained, consistent with the actual survey results on the ground. Our results prove that the method incorporating the HySpex hyperspectral data to invert copper content in detritus is feasible and effective, and provides data and a reference method for obtaining geochemical element distribution in a large area and for reducing key areas of geological exploration in the future.
Drift Reduction of a 4-DOF Measurement System Caused by Unstable Air Refractive Index
Authors: Li Ruijun , Wang Yongjun , Tao Pan , Cheng Rongjun , Cheng Zhenying , Wei Yongqing , Dang Xueming
Published: November 2020

Laser beam drift greatly influences the accuracy of a four degrees of freedom (4-DOF) measurement system during the detection of machine tool errors, especially for long-distance measurement. A novel method was proposed using bellows to serve as a laser beam shield and air pumps to stabilize the refractive index of air. The inner diameter of the bellows and the control mode of the pumps were optimized through theoretical analysis and simulation. An experimental setup was established to verify the feasibility of the method under the temperature interference condition. The results indicated that the position stability of the laser beam spot can be improved by more than 79% under the action of pumping and inflating. The proposed scheme provides a cost-effective method to reduce the laser beam drift, which can be applied to improve the detection accuracy of a 4-DOF measurement system.
Modeling and Implementation of TEG-Based Energy Harvesting System for Steam Sterilization Surveillance Sensor Node
Authors: Daniol Mateusz , Boehler Lukas , Sroka Ryszard , Keller Anton
Published: November 2020

The aim of this work is a proof of concept, that medical Internet of Things (IoT) sterilization surveillance sensors can be powered by using the heat during a steam sterilization procedure. Hereby, the focus was on the use of thermo-electrical generators (TEG) to generate enough power for an ultra-low-power sensor application. Power generation requirement of the sensor was 1.6 mW over the single sterilization cycle. The thermal gradient across the TEG has been achieved using a highly efficient aerogel-foam-based thermal insulation, shielding a heat storage unit (HSU), connected to one side of the TEG. The evaluation of the developed system was carried out with thermal and electrical simulations based on the parameters extracted from the TEG manufacturer’s datasheet. The developed model has been validated with a real prototype using the thermal step response method. It was important for the authors to focus on rapid-prototyping and using off-the-shelf devices and materials. Based on comparison with the physical prototype, the SPICE model was adjusted. With a thermal gradient of 12 °C, the simulated model generated over 2 mW of power. The results show that a significant power generation with this system is possible and usable for sensor applications in medial IoT.