bluuebunny/crossref_metadata_2025 huggingface dataset:
Biochemical, Micronutrient and Physicochemical Properties of the Dried Red Seaweeds Gracilaria edulis and Gracilaria corticata
Authors: Rosemary Thomas , Arulkumar Abimannan , Paramasivam Sadayan , Mondragon-Portocarrero Alicia , Miranda Jose
Published: June 2019

The present study sought to evaluate the nutritional composition and physicochemical properties of two dried commercially interesting edible red seaweeds, Gracilaria corticata and G. edulis. Proximate composition of the dried seaweeds revealed a higher content in carbohydrates (8.30 g/100 g), total crude protein (22.84 g/100 g) and lipid content (7.07 g/100 g) in G. corticata than in G. edulis. Fatty acids profile showed that G. corticata samples contain higher concentrations of saturated fatty acids, such as palmitic and stearic acids, and polyunsaturated ones such as α-linolenic and docosahexaenoic acids. Contrariwise, G. edulis contained higher amounts of monounsaturated oleic acid. Total amino acid content was 76.60 mg/g in G. corticata and 65.42 mg/g in G. edulis, being the essential amino acid content higher in G. edulis (35.55 mg/g) than in G. corticata (22.76 mg/g). Chlorophyll a was found in significantly higher amounts in G. edulis (17.14 μg/g) than G. corticata, whereas carotenoid content was significantly higher in G. corticata (12.98 μg/g) than in G. edulis. With respect to physical properties, both water- and oil-holding capacities were similar in both seaweeds, whereas swelling capacity was higher in G. edulis. In view of the results, the present study suggests that G. corticata and G. edulis contains important nutrients for human health and are possible natural functional foods.
Soliton Fractional Charges in Graphene Nanoribbon and Polyacetylene: Similarities and Differences
Authors: Yang S.-R. Eric
Published: June 2019

An introductory overview of current research developments regarding solitons and fractional boundary charges in graphene nanoribbons is presented. Graphene nanoribbons and polyacetylene have chiral symmetry and share numerous similar properties, e.g., the bulk-edge correspondence between the Zak phase and the existence of edge states, along with the presence of chiral boundary states, which are important for charge fractionalization. In polyacetylene, a fermion mass potential in the Dirac equation produces an excitation gap, and a twist in this scalar potential produces a zero-energy chiral soliton. Similarly, in a gapful armchair graphene nanoribbon, a distortion in the chiral gauge field can produce soliton states. In polyacetylene, a soliton is bound to a domain wall connecting two different dimerized phases. In graphene nanoribbons, a domain-wall soliton connects two topological zigzag edges with different chiralities. However, such a soliton does not display spin-charge separation. The existence of a soliton in finite-length polyacetylene can induce formation of fractional charges on the opposite ends. In contrast, for gapful graphene nanoribbons, the antiferromagnetic coupling between the opposite zigzag edges induces integer boundary charges. The presence of disorder in graphene nanoribbons partly mitigates antiferromagnetic coupling effect. Hence, the average edge charge of gap states with energies within a small interval is e / 2 , with significant charge fluctuations. However, midgap states exhibit a well-defined charge fractionalization between the opposite zigzag edges in the weak-disorder regime. Numerous occupied soliton states in a disorder-free and doped zigzag graphene nanoribbon form a solitonic phase.
Individual Sensitization Pattern Recognition to Cow’s Milk and Human Milk Differs for Various Clinical Manifestations of Milk Allergy
Authors: Schocker Frauke , Kull Skadi , Schwager Christian , Behrends Jochen , Jappe Uta
Published: June 2019

Cow’s milk allergy (CMA) belongs to one of the most common food allergies in early childhood affecting 2–3% of children under 3 years of age. However, approximately 1% of adults remain allergic to cow’s milk, often showing severe reactions even to traces of milk. In our study, we recruited patients with different clinical manifestations of CMA, including patients with anaphylaxis and less severe symptoms. We assessed the sensitization patterns and allergic responses of these subgroups through different immunological and cell-based methods. Sera of patients were investigated for IgE against whole cow’s milk and its single allergens by CAP- FEIA. In a newly developed in-house multiplex dot assay and a basophil activation test (BAT), cow’s milk allergens, in addition to human breast milk and single allergens from cow’s and human milk were analyzed for IgE recognition and severity of CMA in the included patients. Both the CAP-FEIA routine diagnostic and the multiplex dot test could differentiate CMA with severe from milder allergic reactions by means of the patients’ casein sensitization. The BAT, which mirrors the clinical response in vitro, confirmed that basophils from patients with severe reactions were more reactive to caseins in contrast to the basophils from more moderate CMA patients. By means of this improved component-resolved diagnosis of CMA, individual sensitization patterns could be assessed, also taking sensitization against human milk into consideration.
Attenuation of UVB-Induced Photo-Aging by Polyphenolic-Rich Spatholobus Suberectus Stem Extract Via Modulation of MAPK/AP-1/MMPs Signaling in Human Keratinocytes
Authors: Kwon Kyoo-Ri , Alam Md Badrul , Park Ji-Hyun , Kim Tae-Ho , Lee Sang-Han
Published: June 2019

It is well known that ultraviolet light activates mitogen-activated protein (MAP) kinase by increasing the reactive oxygen species (ROS) in the body, enhancing activating protein 1(AP-1) complexes (c-Jun and c-Fos), increasing matrix metalloproteinases (MMPs) and degrading collagen and elastin. In this study, we confirmed that polyphenolic rich Spatholobus suberectus (SS) stem extracts suppressed ultraviolet (UV)-induced photo-aging. The major active components of SS stem extracts were identified as gallic acid, catechin, vanillic acid, syringic acid and epicatechin. The aqueous and ethanolic extracts of the stem of SS (SSW and SSE, respectively) significantly reduced the elastase enzyme activity. Moreover, both extracts were suppressed the ROS generation and cellular damage induced by UVB in HaCaT cells. Our results also revealed that SSE could regulate the expression of MMPs, tissue inhibitor of matrix metalloproteinase (TIMP)-1, collagen type I alpha 1 (COL1A1), elastin (ELN) and hyaluronan synthase 2 (HAS2) at their transcriptional and translational level. Furthermore, SSE was blocked the UVB-induced phosphorylation of mitogen-activated protein kinases (MAPKs), nuclear factor-kappa B (NF-κB) and c-Jun. Moreover, combination of syringic acid, epicatechin and vanillic acid showed strong synergistic effects on elastase inhibition activity, in which the combination index (CI) was 0.28. Overall, these results strongly suggest that the polyphenolics of SSE exert anti-ageing potential as a natural biomaterial to inhibit UVB-induced photo-aging.
Modulation of Saliva Microbiota through Prebiotic Intervention in HIV-Infected Individuals
Authors: Jiménez-Hernández Nuria , Serrano-Villar Sergio , Domingo Alba , Pons Xavier , Artacho Alejandro , Estrada Vicente , Moya Andrés , Gosalbes María José
Published: June 2019

Human immunodeficiency virus (HIV) infection is characterized by an early depletion of the mucosal associated T helper (CD4+) cells that impair the host immunity and impact the oral and gut microbiomes. Although, the HIV-associated gut microbiota was studied in depth, few works addressed the dysbiosis of oral microbiota in HIV infection and, to our knowledge, no studies on intervention with prebiotics were performed. We studied the effect of a six-week-long prebiotic administration on the salivary microbiota in HIV patients and healthy subjects. Also, the co-occurrence of saliva microorganisms in the fecal bacteria community was explored. We assessed salivary and feces microbiota composition using deep 16S ribosomal RNA (rRNA) gene sequencing with Illumina methodology. At baseline, the different groups shared the same most abundant genera, but the HIV status had an impact on the saliva microbiota composition and diversity parameters. After the intervention with prebiotics, we found a drastic decrease in alpha diversity parameters, as well as a change of beta diversity, without a clear directionality toward a healthy microbiota. Interestingly, we found a differential response to the prebiotics, depending on the initial microbiota. On the basis of 100% identity clustering, we detected saliva sequences in the feces datasets, suggesting a drag of microorganisms from the upper to the lower gastrointestinal tract.
Isolation and Molecular Identification of Virulence, Antimicrobial and Heavy Metal Resistance Genes in Livestock-Associated Methicillin-Resistant Staphylococcus aureus
Authors: Dweba Chumisa C. , Zishiri Oliver T. , El Zowalaty Mohamed E.
Published: June 2019

Staphylococcus aureus is one of the most important pathogens of humans and animals. Livestock production contributes a significant proportion to the South African Gross Domestic Product. Consequently, the aim of this study was to determine for the first time the prevalence, virulence, antibiotic and heavy metal resistance in livestock-associated S. aureus isolated from South African livestock production systems. Microbial phenotypic methods were used to detect the presence of antibiotic and heavy metal resistance. Furthermore, molecular DNA based methods were used to genetically determine virulence as well as antibiotic and heavy metal resistance determinants. Polymerase chain reaction (PCR) confirmed 217 out of 403 (53.8%) isolates to be S. aureus. Kirby-Bauer disc diffusion method was conducted to evaluate antibiotic resistance and 90.8% of S. aureus isolates were found to be resistant to at least three antibiotics, and therefore, classified as multidrug resistant. Of the antibiotics tested, 98% of the isolates demonstrated resistance towards penicillin G. High resistance was shown against different heavy metals, with 90% (196/217), 88% (192/217), 86% (188/217) and 84% (183/217) of the isolates resistant to 1500 µg/mL concentration of Cadmium (Cd), Zinc (Zn), Lead (Pb) and Copper (Cu) respectively. A total of 10 antimicrobial resistance and virulence genetic determinants were screened for all livestock associated S. aureus isolates. Methicillin-resistant S. aureus (MRSA) isolates were identified, by the presence of mecC, in 27% of the isolates with a significant relationship (p < 0.001)) with the host animal. This is the first report of mecC positive LA-MRSA in South Africa and the African continent. The gene for tetracycline resistance (tetK) was the most frequently detected of the screened genes with an overall prevalence of 35% and the highest prevalence percentage was observed for goats (56.76%) followed by avian species (chicken, duck and wild birds) (42.5%). Virulence-associated genes were observed across all animal host species. The study reports the presence of luks/pv, a gene encoding the PVL toxin previously described to be a marker for community acquired-MRSA, suggesting the crossing of species between human and livestock. The high prevalence of S. aureus from the livestock indicates a major food security and healthcare threat. This threat is further compounded by the virulence of the pathogen, which causes numerous clinical manifestations. The phenomenon of co-selection is observed in this study as isolates exhibited resistance to both antibiotics and heavy metals. Further, all the screened antibiotic and heavy metal resistance genes did not correspond with the phenotypic resistance.
An Ethical Analysis of Pharmacy Benefit Manager (PBM) Practices
Authors: Drettwan Jacob J. , Kjos Andrea L.
Published: June 2019

The high costs associated with pharmaceuticals and the accompanying stakeholders are being closely evaluated in the search for solutions. As a major stakeholder in the U.S. pharmaceutical market, the practices of pharmacy benefit manager (PBM) organizations have been under increased scrutiny. Examples of controversial practices have included incentives driving formulary status and prohibiting pharmacists from disclosing information on lower-cost prescription alternatives. Ethical investigations have been largely omitted within the debate on the responsibilities of these organizations in the health care system. Ethical analysis of organizational practices is justified based on the potential impact during health care delivery. The objective of this study was to analyze several specific PBM practices using multiple ethical decision-making models to determine their ethical nature. This study systematically applied multiple ethical decision-making models and codes of ethics to a variety of practices associated with PBM-related dilemmas encountered in the pharmaceutical environment. The assessed scenarios resulted in mixed outcomes. PBM practices were both ethical and unethical depending on the applied ethical model. Despite variation across applied models, some practices were predominately ethical or unethical. The point of sale rebates were consistently determined as ethical, whereas market consolidation, gag clauses, and fluctuation of pharmacy reimbursements were all predominantly determined as unethical. The application of using provider codes of ethics created additional comparison and also contained mixed findings. This study provided a unique assessment of PBM practices and provides context from a variety of ethical perspectives. To the knowledge of the authors, these perspectives have not been previously applied to PBM practices in the literature. The application of ethical decision-making models offers a unique context to current health care dilemmas. It is important to analyze health care dilemmas using ethics-based frameworks to contribute solutions addressing complexities and values of all stakeholders in the health care environment.
Modeling of a Double Effect Heat Transformer Operating with Water/Lithium Bromide
Authors: Balderas-Sánchez Itzel N. , Jiménez-García J. Camilo , Rivera Wilfrido
Published: June 2019

Absorption heat transformers are effective systems for a wide variety of applications; however, their main purpose is to upgrade thermal energy from several sources at low-temperature up to a higher temperature level. In the literature, several advanced configurations for absorption heat transformers have been reported which are mainly focused on the improvement of the gross temperature lift by the use of a double absorption process; however, these systems usually offer a reduced coefficient of performance. The present study proposes a new advanced configuration of an absorption heat transformer that improves the coefficient of performance utilizing a double generation process. The operation of the new configuration was numerically modeled, and the main findings were discussed and presented emphasizing the effect of several parameters on the system performance. The highest coefficient of performance and gross temperature lift were 0.63 and 48 °C, respectively. From its comparison with a single-stage heat transformer, it is concluded that the proposed system may achieve coefficient of performance values up to 25.8% higher than those obtained with the single-stage system, although achieving lower gross temperature lifts.
Region Merging Method for Remote Sensing Spectral Image Aided by Inter-Segment and Boundary Homogeneities
Authors: Zhang Yuhan , Wang Xi , Tan Haishu , Xu Chang , Ma Xu , Xu Tingfa
Published: June 2019

Image segmentation is extensively used in remote sensing spectral image processing. Most of the existing region merging methods assess the heterogeneity or homogeneity using global or pre-defined parameters, which lack the flexibility to further improve the goodness-of-fit. Recently, the local spectral angle (SA) threshold was used to produce promising segmentation results. However, this method falls short of considering the inherent relationship between adjacent segments. In order to overcome this limitation, an adaptive SA thresholds methods, which combines the inter-segment and boundary homogeneities of adjacent segment pairs by their respective weights to refine predetermined SA threshold, is employed in a hybrid segmentation framework to enhance the image segmentation accuracy. The proposed method can effectively improve the segmentation accuracy with different kinds of reference objects compared to the conventional segmentation approaches based on the global SA and local SA thresholds. The results of the visual comparison also reveal that our method can match more accurately with reference polygons of varied sizes and types.
Skin Temperatures in Females Wearing a 2 mm Wetsuit during Surfing
Authors: Warner Mackenzie E. , Nessler Jeff A. , Newcomer Sean C.
Published: June 2019

The aim of this investigation was to examine regional skin temperatures in recreational female surfers’ wearing a 2 mm thick neoprene wetsuit while surfing and to compare these results to previously published data collected in males participating in an identical study. Female surfers (n = 27) engaged in surfing for at least 40 min while wearing a commercially available 2 mm full wetsuit. Skin temperature of eight different anatomical locations were measured with wireless iButton thermal sensors. Regional skin temperatures significantly differed (p < 0.001) across almost all anatomical regions. Furthermore, regional skin temperatures significantly decreased across time at all skin regions throughout an average surfing session (p < 0.001). The greatest reduction in skin temperature was observed in the lower leg (−5.4 °C). Females in the current study exhibited a significantly greater skin temperature decrease in the lower back (−15.2% vs. −10.8%, p = 0.022) and lower arm (−13.6% vs. −10.8%, p < 0.001) when compared to previous data published in males. Overall, results of the current study are consistent with data previously published on male recreational surfers. However, the current study provides preliminary evidence that the magnitude of change in skin temperature may differ between male and female recreational surfers at some anatomical locations.
Attitude Toward Sustainable Transport as a Function of Source and Argument Reliability and Anticipated Emotions
Authors: Manca Sara , Fornara Ferdinando
Published: June 2019

The progressive development of mass communication has allowed the understanding and management of the persuasion process in a more systematic way. However, nowadays, persuasive campaigns still hardly result in behavior changes, particularly around concerns of the promotion of more sustainable lifestyles. Thus, it appears essential to investigate which dimensions are more effective in influencing people’s pro-environmental actions. Relying on the conceptual frameworks provided by the elaboration likelihood model (ELM) and the model of goal-directed behavior (MGB), a questionnaire study (n = 380 urban residents) was carried out on the psycho-social antecedents of the intention to use sustainable means of transport. Structural equation modeling showed the mediating role of attitudes toward sustainable transport between ELM persuasion features (i.e., source reliability and argument reliability) and behavioral intention. Positive and negative anticipated emotions, derived from MGB, predict source reliability (the former) and argument reliability (the latter), respectively.
Hybrid Group MCDM Model to Select the Most Effective Alternative of the Second Runway of the Airport
Authors: Turskis Zenonas , Antuchevičienė Jurgita , Keršulienė Violeta , Gaidukas Gintaras
Published: June 2019

Sustainable and efficient development is one of the most critical challenges facing modern society if it wants to save the world for future generations. Airports are an integral part of human activity. They need to be adapted to meet current and future sustainable needs and provide useful services to the public, taking into account prospects and requirements. Many performance criteria need to be assessed to address issues that often conflict with each other and have different units of measurement. The importance of the criteria to evaluate the effectiveness of alternatives varies. Besides, the implementation of such decisions has different—not precisely described in advance—effects on the interests of different groups in society. Some criteria are defined using different scales. Stakeholders could only evaluate the implemented project alternatives for efficiency throughout the project life cycle. It is essential to find alternative assessment models and adapt them to the challenges. The use of hybrid group multi-criteria decision-making models is one of the most appropriate ways to model such problems. This article presents a real application of the original model to choose the best second runway alternative of the airport.
Rational Design of Toxoid Vaccine Candidates for Staphylococcus aureus Leukocidin AB (LukAB)
Authors: Kailasan Shweta , Kort Thomas , Mukherjee Ipsita , Liao Grant C. , Kanipakala Tulasikumari , Williston Nils , Ganjbaksh Nader , Venkatasubramaniam Arundhathi , Holtsberg Frederick W. , Karauzum Hatice , Adhikari Rajan P. , Aman M. Javad
Published: June 2019

Staphylococcus aureus (SA) infections cause high mortality and morbidity in humans. Being central to its pathogenesis, S. aureus thwarts the host defense by secreting a myriad of virulence factors, including bicomponent, pore-forming leukotoxins. While all vaccine development efforts that aimed at achieving opsonophagocytic killing have failed, targeting virulence by toxoid vaccines represents a novel approach to preventing mortality and morbidity that are caused by SA. The recently discovered leukotoxin LukAB kills human phagocytes and monocytes and it is present in all known S. aureus clinical isolates. While using a structure-guided approach, we generated a library of mutations that targeted functional domains within the LukAB heterodimer to identify attenuated toxoids as potential vaccine candidates. The mutants were evaluated based on expression, solubility, yield, biophysical properties, cytotoxicity, and immunogenicity, and several fully attenuated LukAB toxoids that were capable of eliciting high neutralizing antibody titers were identified. Rabbit polyclonal antibodies against the lead toxoid candidate provided potent neutralization of LukAB. While the neutralization of LukAB alone was not sufficient to fully suppress leukotoxicity in supernatants of S. aureus USA300 isolates, a combination of antibodies against LukAB, α-toxin, and Panton-Valentine leukocidin completely neutralized the cytotoxicity of these strains. These data strongly support the inclusion of LukAB toxoids in a multivalent toxoid vaccine for the prevention of S. aureus disease.
An Influenza Virus Hemagglutinin-Based Vaccine Platform Enables the Generation of Epitope Specific Human Cytomegalovirus Antibodies
Authors: Behzadi Mohammad Amin , Stein Kathryn R. , Bermúdez-González Maria Carolina , Simon Viviana , Nachbagauer Raffael , Tortorella Domenico
Published: June 2019

Human cytomegalovirus (CMV) is a highly prevalent pathogen with ~60%–90% seropositivity in adults. CMV can contribute to organ rejection in transplant recipients and is a major cause of birth defects in newborns. Currently, there are no approved vaccines against CMV. The epitope of a CMV neutralizing monoclonal antibody against a conserved region of the envelope protein gH provided the basis for a new CMV vaccine design. We exploited the influenza A virus as a vaccine platform due to the highly immunogenic head domain of its hemagglutinin envelope protein. Influenza A variants were engineered by reverse genetics to express the epitope of an anti-CMV gH neutralizing antibody that recognizes native gH into the hemagglutinin antigenic Sa site. We determined that the recombinant influenza variants expressing 7, 10, or 13 residues of the anti-gH neutralizing antibody epitope were recognized and neutralized by the anti-gH antibody 10C10. Mice vaccinated with the influenza/CMV chimeric viruses induced CMV-specific antibodies that recognized the native gH protein and inhibited virus infection. In fact, the influenza variants expressing 7–13 gH residues neutralized a CMV infection at ~60% following two immunizations with variants expressing the 13 residue gH peptide produced the highest levels of neutralization. Collectively, our study demonstrates that a variant influenza virus inserted with a gH peptide can generate a humoral response that limits a CMV infection.
Spinal extradural meningioma en plaque with nerve root attachment and extracanal (intrathoracic) extension
Authors: Morgan E. , Hakkou M. , Mellaoui A. , Poluyi E. , Ouahabi A. El
Published: June 2019

Meningiomas are relatively common primary spinal tumours, being the second most common intraspinal tumours probably after vertebral haemangioma.It constitutes about 25% of all intraspinal tumours; however, in the presence of extradural spinal lesions, the diagnosis of meningioma is uncommon and often not among the first two considerations. Purely extradural spinal meningioma, especially of the “En plaque” variety, usually simulate malignant disease (metastatic diseases and lymphoma) and may result in inadequate therapy, however, the presence of nerve root attachment is even rarer.Our case report is that of an entirely cervicothoracic extradural en?plaque meningioma (WHO grade 1) with a nerve root attachment (right C7) and intrathoracic extension. We highlighted the issues in diagnosis, operative intervention and long-term follow-up.
The evaluation of long-term screw pull-out rates following posterior thoracolumbar fusion surgery with short and thin pedicle screws
Authors: Kocaman Umit , Yilmaz Hakan
Published: June 2019

Background. The aim of this study was to evaluate screw pull-out rates after fusion operations with short and thin pedicle screws.Methods. A total of 200 posterior lumbar and thoracolumbar fusion operations performed at our clinic with short and thin pedicle screws (5.5x35 mm) were retrospectively evaluated. The patients were assessed with computed tomography postoperatively on the day of surgery and at the 6th month. Single groove retraction of the transpedicular screw was evaluated as pull-out. The results were evaluated by the 'number of pull-out cases / total number of cases' and also the 'total number of pull-out screws / total number of screws used' ratios. Results. There were 112 (56%) female and 88 (44%) male patients with a mean age of 58 years. The total number of screws used in the 200 cases was 1188. There were 88 (7.4%) thoracic pedicle screws, 1056 (88.9%) lumbar pedicle screws and 44 (3.7%) sacral pedicle screws used. No pull-out was found in the control CTs taken postoperatively. Left side T11 and T12 pull-out was observed in one case and left L4 pull-out was observed in another case in the control CTs taken at the postoperative 6th month. Pull-out was observed in 2 (1%) of the 200 cases and 3 (0.25%) of the 1188 screws.Conclusions. All the short and thin pedicle screws used had passed the pedicle length and neurocentral junction. The use of a 5.5x35 mm screws in fusion operations is less invasive than using longer and thicker screws while the pull-out rates may be similar.
Implementasi Cluster Server Pada Raspberry Pi Dengan Menggunakan Metode Load Balancing
Authors: Sujana Aprianti Putri
Published: June 2019

Ketika server mengalami overload, hal ini akan membuat server melambat, efeknya adalah waktu akses layanan bertambah yang akan membuat client tidak nyaman dalam menggunakan layanan yang ada pada server. Cluster server menawarkan solusi agar beban terbagi secara merata, sistem ini memanfaatkan beberapa komputer yang di konfigurasi sedemikian rupa agar dapat berkerja bersama-sama. Hasil dari pengujian cluster server menunjukan peningkatan waktu respon http request sebesar 59% lebih cepat dibandingkan tanpa menggunakan sistem cluster server. Keuntungan lain menggunakan cluster server adalah adanya redudancy, jadi ketika salah satu anggota node tidak aktif maka secara otomatis master node atau load balancer akan memindahkan request menuju node yang masih aktif.
Pembangunan Sistem Electronic Customer Relationship Management pada PT. Beton Elemenindo Perkasa
Authors: Hambali Faizal Zaenal , Witanti Wina , Sabrina Puspita Nurul
Published: June 2019

PT. Beton Elemenindo Perkasa is a company engaged in the construction industry as a provider of precast concrete for infrastructure projects both government and private projects. The company was founded on February 5, 1990. PT. Beton Elemenindo Perkasa markets its products in a conventional way, which comes directly to the customer, but inadequate product and service promo information makes it difficult for the company to retain customers. In addition, the lack of communication media from the company causes a lack of assessment and evaluation of the company's performance in an effort increasing demand will have an impact on decreasing loyalty and if it happens continuously the company will lose customers or switch customers to other companies. Possibility of developing a Customer Relationship Management system at PT. Beton Elemenindo Perkasa will use the waterfall method.

Keyword - Electronic Customer Relationship Management; PT. Beton Elemenindo Perkasa; Waterfall.
Representações no Fluxo Televisivo: a naturalização das “novas tecnologias” no telejornal, na telenovela e na publicidade
Authors: Silva Nathália dos Santos , Piedras Elisa Reinhardt
Published: June 2019

O objetivo desta pesquisa é analisar as representações sobre “novas tecnologias” no fluxo televisivo, considerando o encadeamento entre telejornal, telenovela e publicidade. No âmbito teórico, discutimos a circulação social de representações (MOSCOVICI, 1978[1961]; GOFFMAN,1979; HALL, 1997) na perspectiva analítica do fluxo televisivo (WILLIAMS, 1992[1974]; JENSEN, 1995). Quanto às estratégias metodológicas, o corpus é constituído pelo fluxo de fragmentos da programação do canal que tematizaram o assunto investigado. Inspirados na “análise de curto alcance do fluxo” de Williams (1992) e nas estratégias sugeridas por Jensen (1995), enfatizamos uma abordagem qualitativa mesclada a algumas estratégias quantitativas e adotamos os procedimentos da análise documental. Ao final, elaboramos três categorias referentes à estruturação de representações sobre “novas tecnologias” através do encadeamento de diferentes gêneros televisivos. Com uma ocorrência maior no telejornalismo, na publicidade e, depois, na telenovela, o fluxo representou aparatos, tecnologias de conexão e diferentes plataformas digitais a partir de diferentes ritmos, intensidades e valores associados, contribuindo na naturalização de algumas representações.
Cine y Ocultismo: Apuntes para una visión mágica del cinematógrafo
Authors: Palacios Jesus
Published: June 2019

Este artículo propone una relectura de la historia del cine, que resinifica su relación original y constante con el Ocultismo. Además de la obvia presencia de temáticas esotéricas y paranormales en los argumentos cinematográficos, ese artículo pretende dilucidar una serie de correspondencias profundas entre el arte y la técnica cinematográficos y las áreas del conocimiento de las que se ocupa el Ocultismo. En este sentido, desvela que no sólo el cine fantástico y de terror aprovecha el acervo esotérico, sino que este nutre también terrenos bien diferentes como el documental, el ensayo visual, el cine experimental e incluso comedias o filmes de animación, rebasando a menudo la mera inclusión de tópicos ocultistas para convertirse en una simbiosis formal, estética e incluso ética, en la que el cine, medio y fin, instrumento y vehículo, adquiere para sí las funciones y el prestigio de una vía mágica de conocimiento.
Fotografia Imóvel?
Authors: Cholodenko Alan
Published: June 2019

A questão é: a fotografia é imóvel? E uma questão correlata: “é a fotografia ainda fotografia imóvel? ”. Nesse ensaio, o autor tenta oferecer algumas “respostas” para estas questões, incluindo a mobilização de questões já desenvolvidas pelos teóricos da fotografia e utilizando-se de algumas fotografias, quase todas de autoria de Jean Baudrillard – seu mundo paralelo de imagens instantâneas análogas a seus textos instantâneos, seus fragmentos de imagem e de pensamento. A questão da imobilidade é, para o autor, uma questão de animação, de movimento e de vida. A fotografia, toda fotografia, fotografia “como tal”, é uma forma de animação. O que permitiria ao autor argumentar: não somente a animação é uma forma de filme, mas o fil me, todo filme, é uma forma de animação. Isso inclui a fotografia como uma forma de filme.
Identidades no contemporâneo: uma reflexão a partir da narrativa audiovisual “Meia-Noite em Paris”
Authors: Haubrich Gislene Feiten
Published: June 2019

O artigo busca compreender implicações da noção de nostalgia à representação identitária dos sujeitos na contemporaneidade, tendo como base o drama da personagem Gil Pender, na narrativa audiovisual Meia-Noite em Paris (2011), de Woody Allen. Justifica-se o estudo diante da conexão entre nostalgia e devaneio ao estudo das identidades, além da relevância atribuída pelos sujeitos ao sentimento nostálgico na reconstituição de memórias que fundamentam seu viver. Nesta perspectiva, desenvolve-se uma pesquisa exploratória, de cunho bibliográfico e enfoque em análise fílmica. O referencial teórico é composto por Bachelard (1994; 1998), que orienta o entendimento acerca de tempo e de espaço, basilares à análise da ideia de nostalgia; Hall (2003; 2006) para a compreensão das noções de identidade e representação. Já as linguagens fílmicas serão estudadas a partir da elucidação de Gardies (2008) e Gaudreault e Jost (2009). Assim, o estudo percebe a nostalgia enquanto convite ao transitar pelo passado para depreender o presente. O sentimento nostálgico permite o acesso referencial aos espaços que podem orientar a construção de certezas (sempre provisórias) às vivências dos sujeitos, sendo a representação de sua identidade resultado dessa construção intelectual.
A perspectiva social das competências midiáticas: reflexões sobre participação e interação das crianças na escola
Authors: Thédiga de Miranda Lyana , Fantin Monica
Published: June 2019

O texto busca refletir sobre o entrelaçamento das competências midiáticas e competências relacionais de crianças em situações de produção audiovisual a partir de propostas didáticas construídas com base na metodologia dos Episódios de Aprendizagem Situados (EAS).Sob uma perspectiva social, nos interessa apresentar como as crianças, um total de 53 alunos de duas escolas públicas de Florianópolis, mobilizaram a empatia e a postura proativa em situações colaborativas consideradas complexas e condicionadas à motivação para a participação. Metodologicamente, seguimos a abordagem multimétodos e da bricolagem que combinou, durante todo o ano letivo de 2015,observação na escola,  intervenção didática, grupo focal com estudantes, caderno de campo e aplicação de um questionário.Entre os resultados, destacamos que a reflexão sobre as competências em uma perspectiva sistêmica e relacional possibilita estabelecer indicadores assertivos, capazes de promover e avaliar fatores constitutivos da interação e competência social entre as crianças na escola. Conclui-se que,ao adotar a metodologia EAS na busca pelo fomento de competências midiáticas sob uma perspectiva social, essa escolha evidencia a necessidade de reestruturação das relações comunicativas entre professores, alunos e ambiente,  o que denota a importância de se promover as competências midiáticas entrelaçadas às competências relacionais.
Universitarios, ciudadanía y competencias mediáticas
Authors: Teresa Quiroz Velasco María
Published: June 2019

La universidad del siglo XXI cambia y se transforma. Ceden los muros que conservaban y atesoraban el saber, en un tiempo que demanda con urgencia que el conocimiento se transfiera para mejorar la calidad de vida de nuestras sociedades, así como las oportunidades para ser más equitativas. La función social de la universidad –pública o privada– se hace más explícita, y su vocación por el bien común incluye a la política como preocupación y práctica dentro y fuera del campus. Entre los años 2015-2017, en la Universidad de Lima iniciamos una investigación bajo el auspicio de su Instituto de Investigación Científica, en la cual se exploran las percepciones y discursos de los estudiantes universitarios de Lima Metropolitana. Para el estudio se aplicó una encuesta a 403 universitarios y se realizaron 6 grupos focales, con jóvenes de universidades públicas y privadas, hombres y mujeres, de carreras de ciencias y humanidades y diferenciados en tres categorías: apolíticos, interesados en política y organizados en partidos. En este artículo se alcanzarán y analizarán algunos resultados del estudio, que recogen importantes aspectos de la relación de los universitarios con la política. Del mismo modo, se buscará interpretar el tipo de vínculo que tienen con el país, los medios a través de los cuales se informan, y sus percepciones y discursos en torno al lugar que ocupan en la universidad.
Competencias mediáticas audiovisuales en Ecuador y perspectivas a futuro
Authors: Rivera Rogel Diana , Mendoza-Zambrano Damian , Marín Gutiérrez Isidro , Velásquez Benavides Andrea Victoria
Published: June 2019

La educación mediática es necesaria para derrumbar las barreras que se han producido en la educación. Este tema está poco explorado en Ecuador. Las TIC pueden ser la llave para resolver gran parte de los problemas educativos y para dar un rápido impulso a la calidad de la enseñanza. Para conocer las competencias mediáticas en escuelas, colegios y universidades de Ecuador diversas universidades ecuatorianas han emprendido una serie de investigaciones en competencias mediáticas, cuyos resultados muestran que se tiene que dar una mayor importancia al componente pedagógico que al tecnológico.
Gênero e sexualidade na época do pluralismo: um desafio às religiões ins-titucionalizadas e universalistas
Authors: Danner Leno Francisco
Published: June 2019

Defenderei que as religiões institucionalizadas e universalistas, ao estilo da Igreja Católica, possam abandonar – ou pelo menos relativizar – seus discursos, valores e controles sobre gênero e sexualidade, de modo a servirem como plataforma de enfrentamento em relação a todas as formas de violência envolvendo gênero e sexualidade, muitas delas fundadas em possíveis interpretações de textos religiosos. Isso significa que as instituições religiosas de um modo geral e a Igreja Católica em particular precisarão renunciar às fundamentações essencialistas e naturalizadas nesse campo da vida cotidiana, deixando as questões de gênero e de sexualidade como fazendo parte irremediável da vida privada, uma conquista fundamental do processo de modernização ocidental e das democracias nele fundadas, baseado na secularização das instituições, na liberdade individual e no pluralismo dos estilos de vida. Esse abandono ou moderação discursiva acerca das questões de gênero e sexualidade possibilitaria uma renovação importantíssima às instituições religiosas e, na verdade, é, conforme acredito, o caminho por excelência que elas devem tomar neste século XXI.
Marcos Legislativos de Regulação do Religioso no Brasil: Estatuto da Igualdade Racial, Acordo Brasil-Vaticano e Lei Geral das Religiões
Authors: Scola Jorge , Giumbelli Emerson
Published: June 2019

Examinamos três instrumentos normativos produzidos ou aprovados no âmbito do legislativo federal brasileiro: o Estatuto da Igualdade Racial, o Acordo Brasil-Vaticano e o projeto conhecido como Lei Geral das Religiões. O Estatuto da Igualdade Racial (Lei 12.288/2010) foi encampado pelo Estado brasileiro no quadro de discussões sobre ações afirmativas e o modo como enquadra os direitos das “religiões de matriz africana” a partir de uma perspectiva étnica constrói continuidades em relação à via de afirmação diferencialista destas no espaço público. O Acordo Brasil-Vaticano (Decreto 7107/2010), tramitado no Congresso Nacional após negociações com o governo federal, está voltado para as condições de existência da Igreja Católica, com um tom particularista na leitura da produção de direitos religiosos. Reação das “bancadas evangélicas” em relação à conquista dos católicos, a Lei Geral das Religiões (PL 160/2009) fala em nome de todos os grupos religiosos na garantia de direitos. A análise busca contextualizar os textos normativos, marcando as passagens e mudanças entre perspectivas generalistas e particularistas. Contribui para caracterizar, em termos de regulação do religioso, os arranjos propostos por estes instrumentos entre religiões e o Estado, tendo como foco os entendimentos acerca do princípio da liberdade religiosa.
Cidadania e gratuidade: uma recepção do documento Do Conflito à Comunhão no horizonte da Teologia Pública
Authors: Zeferino Jefferson
Published: June 2019

Este trabalho pensa caminhos possíveis de desenvolvimento teológico diante do marco dos 500 anos da Reforma que traz consigo elementos ecumênicos inéditos na história das igrejas. Desta forma, percebe-se o ecumenismo como possibilidade de se pensar as heranças do protestantismo no horizonte das demandas atuais da sociedade. Como meio de aproximação emerge aquilo que se tem chamado de Teologia Pública em especial a partir da assim chamada Teologia da Cidadania. A partir da análise do documento Do Conflito à Comunhão (DCAC), percebe-se a graça como elemento fundante de sua elaboração. Aspecto também presente na formulação barthiana sobre a graça. Enquanto resultado da relação dialógica das referências citadas, percebem-se a gratuidade e o serviço como elementos propulsores para um pensamento teológico coerente com seus variados públicos (igreja, academia, sociedade).
Hubungan Pola Asuh Orang Tua dan Pemberian Stimulus Alat Permainan Edukatif (APE) Terhadap Perkembangan Motorik Halus Anak di PAUD Kelurahan Sendangguwo
Authors: Siti Nurhayati Sabatini Kusuma Dewi, Witri Hastuti Witri
Published: June 2019

Berdasarkan data WHO di Indonesia pada tahun 2012 jumlah anak yang diberikan permainan edukatif  pada tahun 2010 mencapai hingga 24.120 jiwa dan pada tahun 2011 mencapai 25.100 jiwa. Cakupan deteksi dini tumbuh kembang anak balita tingkat Provinsi Jawa Tengah pada tahun 2012 sebesar 35,66%, hal ini Jauh di bawah target yang ditetapkan yaitu 90%. Mendeskripsikan hubungan pola asuh orang tua dan pemberian stimulus APE terhadap perkembangan motorik halus anak usia 3-5tahun di PAUD wilayah kelurahan Sendangguwo Semarang. Metode penelitian ini menggunakan penelitian kuantitatif dengan pendekatan analitik korelasi. Pengumpulan data dilakukan sendiri oleh peneliti dan data yang diperoleh dianalisa secara univariat dan bivariat dengan menggunakan uji chi-square dengan hasil penelitian yang menunjukkan (p= 0.000 dan p= 0.000  dengan α= 0,05). Ada hubungan pola asuh orang tua dan pemberian stimulus APE terhadap perkembangan motorik halus anak usia 3-5 tahun di PAUD wilayah kelurahan Sendangguwo Semarang.THE RELATIONSHIP OF PARENTING STYLE AND THE PROVIDING OF EDUCATIONAL TOYS (APE) WITH THE FINE MOTORIC DEVELOPMENT CHILDREN IN SENDANGGUWO  AbstractBased on data from the in Indonesia in 2012 the number of children who are given educational toys on in 2010 amounted to 24 120 inhabitants and in 2011 reached 25,100 people. The stimulation toys on children is very helpful in the development of the child from an early age, with the knowledge of good parents, then the need for child development will be fulfilled Sixteen percent of toddlers Indonesia impaired growth, good development of fine and gross motor, hearing loss, less intelligence and delays , Coverage of early detection of growth and development of children under five levels of Central Java province in 2012 amounted to 35.66%, it is drastically below the set target of 90%. The purpose of this research was to describe the relationship of parenting style and the providing of educational toys (APE) with the fine motoric development of 3-5 years old children at early childhood education in sendangguwo semarang. This study was a quantitative study of correlation analytic approach. Collection of the data was done by the researcher and the data obtained were analyzed using univariate and bivariate using chi-square test with the results of studies showing (p= 0.000 and p= 0,000 with α= 0,05). Based on the results of  research and discussion can be concluded that there is a relationship of parenting style and the providing of educational toys (APE) with the fine motoric development of 3-5 years old children at early childhood education in sendangguwo semarang. Keywords ;Parenting, The giving of Stimulus Educational Toys , finemotorics
Bayam Merah untuk Peningkatan Kadar Hemoglobin Remaja Putri Kelas XII SMK Al-Islam Kudus
Authors: Faridah Umi
Published: June 2019

Latar Belakang: Anemia adalah salah satu masalah gizi utama yang terjadi di Indonesia, khususnya anemia. Anemia menonjol pada masa anak-anak sekolah terutama  remaja  putri.  Remaja  putri  berisiko  tinggi  terjadi anemia, karena pada masa remaja terjadi peningkatan kebutuhan zat besi akibat adanya pertumbuhan dan masa menstruasi. Kegiatan di sekolah, perkuliahan maupun berbagai aktifitas organisasi dan ekstrakurikuler yang tinggi akan berdampak pada  pola  makan  yang  krang  teratur,  selain  itu  kebiasaan  mengkonsumsi minuman  yang  menghambat  absorbsi  zat  besi  akan  mempengaruhi  kadar hemoglobin seseorang. Penelitian ini untuk mengetahui pengaruh pemberian bayam merah sebagai peningkatan kadar Hb pada remaja putri yang mengalami anemia di SMK Al-Islam tahun 2016. Jenis penelitian ini menggunakan jenis penelitian quasy eksperimental dengan pendekatan pre-post test with control grup. Sampel dalam penelitian ini sebanyak 20 responden dengan menggunakan teknik random sampling. Uji statistik yang digunakan wilcoxon signed rank tes dengn nilai ρ value = 0.005 sehinggasimpulkan ada pengaruh yang signifikan (ρ value 0.005 < 0,05) bayam merah dalam membantu menaikkan kadar zat besi dalam darah sehingga membantu mencegah anemia. Ada pengaruh pemberian bayam merah sebagai upaya peningkatan kadar hemoglobin pada remaja putri yang mengalami anemia  di SMK Al-Islam Kudus tahun 2016.   Kata Kunci:  BayamMerah; Hemoglobin; Anemia
Hubungan Dukungan Perawat dan Dukungan Keluarga dengan Tingkat Kecemasan Pasangan Hidup Pasien yang Dirawat Di Ruang ICU Rumah Sakit Wilayah Kabupaten Blora
Authors: Widiati Amrih
Published: June 2019

Gejala kecemasan baik yang bersifat akut maupun kronik (menahun) merupakan komponen utama bagi hampir semua gangguan jiwa (psychiatric disorder). Jumlah orang yang menderita gangguan kecemasan baik akut maupun kronik mencapai 5% dari jumlah penduduk, dengan perbandingan antara wanita dan pria 2 banding 1. Diperkirakan antara 2-4% diantara penduduk suatu saat dalam kehidupannya pernah mengalami gangguan cemas. Untuk mengetahui hubungan antara dukungan perawat dan dukungan keluarga dengan tingkat kecemasan pasangan hidup pasien yang dirawat. Jenis penelitian kuantitatif analitik. Desain penelitian adalah cross sectional. Populasi dalam  penelitian ini adalah jumlah pasangan hidup pasien di ICU Rumah Sakit Wilayah Kabupaten Blora bulan Desember 2016 sebanyak 32 pasien. Sampel dalam penelitian ini adalah pasangan hidup pasien di ICU Rumah Sakit Wilayah Kabupaten Blora pada bulan Januari 2017 sebanyak 35 pasien. Teknik sampling menggunakan purposive sampling. Uji statistik menggunakan uji Korelasi Rank Spearman. Ada hubungan antara dukungan perawat dengan tingkat kecemasan pasangan hidup pasien yang dirawat (P-value = 0,039). Ada hubungan antara dukungan keluarga dengan tingkat kecemasan pasangan hidup pasien yang dirawat (P-value = 0,005). Rumah sakit membuat standar operasional prosedur pemberian dukungan pada pasien kritis untuk mengurangi tingkat kecemasan pada keluarga.