bluuebunny/crossref_metadata_2025 huggingface dataset:
Hypothyroidism in Children with Β-Thalassemia at a Tertiary Hospital of South Punjab, Pakistan
Authors: Batool Tayyaba , Irim Shomaila , Naeem Malik Muhammad , Mehmood Badar , Younas Nadeem Shahid , Khan Muhammad Irfan , Nadeem Khadija
Published: August 2022

Objective: To determine the prevalence of hypothyroidism among children with β-thalassemia major. Study Design: Cross-sectional study. Place and Duration of the Study: The Department of Hematological Disorder, Thalassemia and Bone Marrow Transplantation Centre, and Department of Biochemistry, Bahawal-Victoria Hospital, Quaid e Azam Medical College”, Bahawalpur, Pakistan from 1st January 2021 to 31st December 2021. Methodology: A total of 125 children of both genders (2 to 18 years) with diagnosis of β-thalassemia major were analyzed. Two ml blood sample under strict aseptic conditions was obtained from every study participant and sent to Institutional Pathological Laboratory for thyroid-stimulating hormone (TSH), T3, and T4. Results: In a total of 125 children with β-thalassemia major, 78 (62.4%) were male. Overall, mean age was 8.57±4.75 years while 57 (45.6%) children were aged between 6 to 10 years. Residential status of 84 (67.2%) children was rural. Parental consanguineous marriages were reported in 91 (72.8%) patients. Mean TSH, T3 and T4 levels were calculated to be 3.27±1.38 pmol/L, 4.71±0.75 pmol/L and 11.80±2.38 pmol/L respectively. Hypothyroidism was noticed in 38 (30.4%) children. Conclusion: Prevalence of hypothyroidism in children with β-thalassemia major was high. Early identification and management of hypothyroidism in β-thalassemia major may improve overall quality of life among these affected children Keywords: Β-thalassemia major, hypothyroidism, thyroid-stimulating hormone.
Predominant Lip Print Pattern Found among Female Students and Employees of Peshawar Medical College
Authors: Mehmood Ijaz , Azeem Muhammad Tariq , Haq Rizwan Ul , Haq Ikram Ul , Yasmin Rubina Salma , Subhani Ahmed
Published: August 2022

Objective: The objective of this study is to determine the predominant lip print pattern found among female students and employees of Peshawar medical college. Design: It was a cross-sectional study. Study Settings: This study was conducted at Forensic Medicine Laboratory of Peshawar Medical College from November 2021 to April 2022. Material and Methods: A total of 107 (74 females, and 33 employees) voluntary participants both students and employees were included in the study. Lip prints were be obtained from them using lipstick and cellophane tape, and studied in the presence of lip print expert. The lip print patterns were classified and frequencies determined. Results: Overall pattern, type V (26.62%) and type III (19.58%) were the most common ones. There was no significant difference between the ethnicity. Conclusion: It might be said that lip prints are distinctive, and that using them to identify people. The results showed that print of any two lips were not matched exactly. The patterns did not reveal any significant variability with regards to gender or ethnicity. Keywords: Lip Prints, Classification, Pattern Types, Cheiloscopy
Topical Vs Pribulbar Anesthesia in Patients Undergoing 23 Guage ,Three Ports Removal of Sillicone Oil
Authors: Shahid Muhammad Hamza , Rashid Faisal , Tauqeer Saba , Ali Rabab , Farooq Muhammad Talha , Aleem Nouman
Published: August 2022

Objective: To compare safety as well as efficacy of topical anesthesia against peribulbar anesthesia for patients undergoing three ports pars plana removal of silicone oil . Background: Silicone oil is used as a temponarding agent for vitreoretinal procedures and have to be removed according to the duration of temponard required as it is associated with complications like development and acceleration of cataract devlopment , secondary open angle glaucoma and corneal decompensation. It can be removed via three port 23 gauge ROSO procedure both under topical and peribulbar anesthesia. Patients & Methods: 40 eyes from 40 patients who underwent three port ROSO with a 23 gauge port system were randomised into two groups of 20 patients each for this study. In group A eyes was operated under topical anesthesia using soaked cotton wisk with 0.5 % proparacaine hydrochloride , placed for five minutes in superior and inferior fornix before the start of surgery and the group B was operated under peri bulbar block with 4 ml of bupivacaine given five minutes before the start of surgical procedure. Pain scoring charts were used by patients to rate their pain after the procedure. Results: The patients in this study had a mean age of 58.46 ±3.62 years, with a range of 30-65 years. 40 individuals were treated, with 26 being male and 14 being female. The mean pain score for patients in topical anesthesia group was 3.8+- 0.5 and the mean pain score in peribulbar block group was 2.2+-0.2 with a p value of 0.01. Conclusion: Peribulbar block is superior to topical anesthesia in patient comport for patients undergoing three port ROSO procedures. Keywords: ROSO, Silicone oil, peribulbar, Topical anesthesia, Bupicaine, Proparacaine hydrochloride.
Perfil empreendedor dos discentes dos cursos de ciências agrárias da Universidade Federal do Pará no município de Altamira
Authors: Santos Ivoneia de Freitas dos , Silva Sandra Andréa Santos da , Santos Marcos Antônio Souza dos , Calvi Miquéias Freitas , Loureiro João Paulo Borges de , Melo André dos Santos
Published: August 2022

O artigo analisa as características empreendedoras dos discentes dos cursos de Engenharia Agronômica e Engenharia Florestal da Universidade Federal do Pará, Campus de Altamira. Utilizou-se um questionário aplicado via online, baseado na escala do Potencial do Perfil Empreendedor (PPE). Participaram 120 respondentes, correspondendo a 31,33% do total de discentes matriculados, 63% do curso de Engenharia Agronômica e 37% do curso de Engenharia Florestal, sendo 53% do sexo feminino e 47% do sexo masculino. Os resultados indicam que os discentes possuem características médias para as dimensões risco profissional, inovação, relacionamento, dedicação e estratégia e para as dimensões pensamento analítico e desafio apresentaram características baixas. Em termos gerais os discentes apresentaram um nível médio quanto ao perfil empreendedor. O ensino do empreendedorismo incentiva e fortalece a formação dos profissionais que pretendem ingressar no mercado de trabalho como empreendedores e gestores dos seus próprios negócios. Assim, sugere-se que estes cursos aprimorem suas estruturas curriculares, incorporando mais componentes voltados ao empreendedorismo, economia e gestão de negócios, visando potencializar o perfil empreendedor desses futuros profissionais.
structures of the derivatives and their significance (The Hyperbolic Patterns) in the book of Aljaratheem Ascribed to Ibn Qutaiba Al-Denyouri (Deceased 276 H.)
Authors: Farahan Meelad Abdullah , Tahseen Hadeel R.
Published: August 2022

This research paper deals with the study of the structures of the derivatives, where in which I dealt with a one of the Arabic language's derivatives which is known by (The Hyperbolic Patterns), and this is because my great passion in dealing with the semantic morphological studies. In this study, I dealt with the semantic morphological side of the structures that indicate the hyperbolic patterns in its comprehensive terminology that the ancient and late morphologists have had formulated. The paper is divided into two topics: First Topic: the regular structures of the Hyperbolic Patterns.Second Topic: the anecdotal structures of the Hyperbolic Patterns.
Correlation of sounds between the self and the other
Authors: Jimaa Roa Bashir , Ali A. P. D. Shaimaa Jabbar
Published: August 2022

This research deals with the ideological thought among the narrator and the characters in the writer’s texts, Iraqi expatriate (Mohammed Habari) .  In this research, we sought to reveal the ideological collision in presenting ideological visions, meaning that revealing the plurality and difference in opinions to reveal the hidden texts of a crisis reality in which the language of fear and death transcends. The search consists of two parts, The first is theoretical, in which it reviews the nature and repercussions of this interdependence, and the other is practical, in which I sought to analyze some texts that deal with this difference.
Impact of climate change and the vulnerability of small-scale fisheries communities
Authors: Manoj Kumar K. N , Lukkumanul Hakkim S , Jeyaraaj T. R. , Kumar B. Pradeep
Published: August 2022

The Climate change affects fishing globally, and the world’s 100 million small-scale fisheries (SSF) are no exception. Despite the high number of SSFs worldwide and their significant economic contributions, SSFs often go understudied. This study aims to understand the impact of climate vulnerabilities among small scale fishing communities.
Awareness and opinion of health professionals about various aspects of the implementation of HDSS
Authors: Charak Garima , Kotwal Suresh
Published: August 2022

Introduction: The lack of appropriate health information obstructs population health assessments, as well as the development and evaluation of healthcare interventions. Surveillance is sometimes used interchangeably with epidemiology in its broadest definition, which is understandable. Surveillance, on the other hand, maybe considered to have evolved into a separate discipline from epidemiology. Objective: To study the Awareness and opinion of health professionals about various aspects of the implementation of HDSS in the defined rural community of district Jammu. Result: The present study was carried out in the Miran Sahib Zone of RS Pura Block, out of which six villages were selected randomly. The study surveyed 20 health professionals' over 3.56 km2 area of rural field practice area out of which 12 HPs had experienced less than 10 years while others had more than 10 years’ experience. The majority of health professionals were aware of various population enumeration methods while a small proportion of health professionals' about 25% considers the data generated by such systems to be useful for policy planning and prioritizing health services in a particular area.
Design of IoT based mobile AQI monitoring kit
Authors: Sivakumar S , Ramya V
Published: August 2022

Air quality is the consequence of interaction among several intricate factors involved in chemical reactions, and emissions from natural and anthropogenic sources. Pollution sources like industrial region, traffic zones, mines etc impose higher pollution levels. Appropriate measures and steps for reducing the pollution need to be taken for the well-being of people living nearer to these regions, with the fast pace of air pollution growth, the toxic levels in air need to get quantified accurately. The proposed MyAmbiAQI kit serves as an affordable and reliable solution for measuring the air quality index.it employs IoT modules and sensors in a centralised, portable and battery powered hub. The live responses from the sensors are acquired by the developed kit for precise monitoring of air quality. The data is sent to the cloud instantly using Thingspeak API and MQTT protocol.  A visualization of data is made from the cloud dashboard there by having a constant check on the air quality around us.  It is a monitoring device undesigned by WSN, and IoT based method design. Interior performance assessments and the comparison among these categories were performed with respect to their architecture and the incorporated tools.
Tinnitus in elderly rural population of Salem district Tamilnadu
Authors: Remanan Arsi , Shivakumar Shivakumar
Published: August 2022

Background: Most patients with both tinnitus and hearing loss report that the frequency of the tinnitus correlates with the severity and frequency characteristics of their hearing loss, and that the intensity of the tinnitus is usually less than 10 dB above the patient's hearing threshold at that frequency. Some patients who have central auditory processing disorders and have difficulties understanding speech in noise report experiencing tinnitus even though their pure-tone audiometric thresholds are normal. Less prevalent forms of tinnitus, such as those involving well-known musical tunes or voices without understandable speech, occur among older people with hearing loss and are believed to represent a central type of tinnitus involving reverberatory activity within neural loops at a high level of processing in the auditory cortex. Methodology: Present study is a longitudinal study conducted at ENT OPD, VMKV MEDICAL COLLEGE AND HOSPITAL, SALEM among 500 patients attending ENT OPD for complaints of tinnitus for a period of 2 years. Data entry and analysis: Data collected was entered in Microsoft excel and analyzed using SPSS version 20.0.Qualitative variables were expressed in percentage and Quantitative variables were expressed in mean and standard deviation.
Study of clinical profile of physiological and hematological findings in patients with chronic bronchitis and emphysema with cardiac complications
Authors: Masih John , Sharma Ramesh Kumar , Azad Khemlal , Tekam Sharda Pratap Singh
Published: August 2022

Introduction: Chronic bronchitis is a symptom of chronic obstructive pulmonary disease (COPD). Chronic bronchitis is one of a number of lung conditions included in this group. These conditions can obstruct lung airflow and lead to breathing issues. Chronicbronchitis and emphysema are the 2 most prevalent diseases associated with COPD. Method: The investigation was carried out at the Government Medical College in Jagdalpur, Chhattisgarh's Bastar district. Cross sectional study was the method used. 32 subjects in all were enrolled in this investigation. The participants in the study ranged in age from 35 to over 70. Each person who was a part of this study signed an informed consent form. In this study, people between the ages of 35 and beyond 70 were included. Result: In comparison to female individuals, male subjects were more. More than 50% of participants reported having trouble breathing, while 12(37.5%) of them also reported having chest pain. In addition, 15 of the subjects displayed indications of tachypnea, while 10 of them had tachycardia, and 7 of them had cyanosis. Twenty patients had neutrophilia, ten had lymphocytosis, two had eosinophilia, and just one had leucocytosis.
Role of siravyadha in gridhrasi (sciatica)
Authors: Dhule Mukund S. , Desai Pradeep G.
Published: August 2022

In our daily therapeutic practise, vitavyadhi is one of the most common health issues, and gridhra is one of them. It is characterised by discomfort in the buttock, thigh, leg, or foot that is searing, stinging, or numbing. Low back discomfort may or may not be related to it. Gridhrasi appears to affect both the sedentary and physically demanding patient types. Siravyadha is stated in the Chikitsasutra of Gridhrasi by CharyaCharaka, Sushruta, VagbhattaYogratnakara, and Bhela. A proper siravyadha manifests as lightness in the painful areas of the body, a decrease in pain, a lessening in vyadhi intensity, and a joyful disposition. Siravyadha is typically performed when a disease has a prominently painful symptom. A study was created to assess the effectiveness of siravyadha in Gridharasi. The goal of the study was to determine how well Siravyadha managed the symptoms of Gridhrasi. 10 patients with symptoms of Gridhrasi and fit for Siravyadha were chosen. Siravydha was performed after dravasnigdhayavagupana along with sthanikasnehana and swedana were incorporated and samyakstravitlakshanas were observed. The patient data was evaluated before the siravyadha procedure, immediately after the procedure and on 10th day as a follow up routine. The findings were statistically tabulated using paired ‘t’ test.
Dissolution enhancement of Enzalutamide by solid dispersion approach
Authors: Bagul Kunal , Mundada Atishkumar
Published: August 2022

Enzalutamide (ENZ) is a BCS class II, fast crystallizing, a hydrophobic compound that has solubility limited absorption in vivo. Ternary solid dispersion of Enzalutamide was prepared with water-soluble polymers Soluplus (SOL) and Poloxamer P 188 (POL) by solvent evaporation spray drying technique. Initially, different ratios of Soluplus: Poloxamer and solvents were used to prepare Ternary solid dispersions of Enzalutamide and evaluated for the dissolution enhancement property. The prepared solid dispersion was characterized by FTIR spectroscopy, Differential scanning calorimetry (DSC), X-ray diffraction (XRD) analysis, Scanning electron microscopy (SEM), Particle size distribution (PSD) by Malvern and Physico-chemical analysis. FTIR spectroscopy shows that there was no interaction between the ENZ and polymers. DSC and XRD analysis show that conversion to amorphous form of ENZ in ternary SD, which enhances the dissolution rate. In vitro dissolution studies and Ex-vivo intestinal absorption studies clearly show that the prepared solid dispersion enhanced the dissolution and ex-vivo intestinal absorption of ENZ compared with pure ENZ.
Feasibility of ultrasonography compared to plain radiography in detection of pneumoperitoneum in patients presenting with acute abdominal pain in the ED
Authors: Ali Fatma A Abdalla , Nassar Esraa H , Aboelnasr Roeya M , Nasreddin Mohamed E , Elshafey Mohamed H , Elafifi Mahmoud A , Elheniedy Mohamed A
Published: August 2022

Background: Pneumoperitoneum is frequently considered one of the commonest surgical emergencies due to its association with gastrointestinal perforation that can result in peritonitis, septic shock, multiorgan failure and death. Accurate and Timely detection of these emergencies is of paramount importance in the management and outcome of the patients. Thus prompt diagnosis is a vital to avoid unnecessary interventions. Objectives: The study aimed to verify the feasibility and usefulness of Ultrasound in the diagnosis of pneumoperitoneum through comparing both Ultrasound and plain radiography findings with the intraoperative findings (the gold standard diagnosis). Methodology: The study was carried out in the Emergency Medicine and Traumatology department at Tanta University Hospitals in the period from September 2019 to September 2021, included eighty three adult patients presented with acute abdominal pain with suspected gastrointestinal perforation. Ultrasound examination was performed by the emergency physician and Plain radiography (erect or lateral decubitus) was done as an important diagnostic tool in acute abdominal pain. All enrolled patients underwent surgical intervention. Results: Sensitivity of ultrasound was higher than that of plain radiography in the diagnosis of pneumoperitoneum (89.39% and 86.63% ) respectively. While plain radiography was more specific than ultrasound (88.24% and 94.12% ) respectively.
Tele-education and adaptive behavior with autism spectrum disorder, in children from 1 to 5 years old
Authors: Cotrina-Aliaga Juan Carlos , Gallardo-Lolandes Yanina , Maita-Cruz Yoni Magali , Flores-Sotelo William Sebastián
Published: August 2022

This research aims to determine the relationship between tele-education and adaptive behavior in autism spectrum disorder in children aged 1 to 5 years. To do this, a cross-sectional, descriptive and correlative non-experimental design study was carried out, the study population consisted of 120 people, and the sample was of a non-probabilistic census type. For data collection, a tele-education survey and an adaptive behavior survey were produced, both with high levels of reliability. Statistical treatment included connection tables, bar graph, analysis and interpretation. For validation, we used Spearman's confirmation coefficient, Rs=0.730, which shows a high positive confirmation with p=0.003. Therefore, it is concluded that in the National Institute of Rehabilitation-Chorrillos there is a significant relationship between tele-education and adaptive behavior in children from 1 to 5 years old.
Pattern of pressure ulcers in a tertiary hospital in south-south Nigeria
Authors: Ohiaeri I. C. , Otene C. I. , Akpo E. E. , Asaboro S. , Akalawu M. U.
Published: August 2022

Background: Pressure ulcers are a common cause of increased morbidity in patients who are bedridden or wheelchair-bound. Objectives: This is to look at the pattern of pressure ulcers in our facility with the objectives to determine the demographic distribution such as age and sex, sites and stage of the ulcers, co-morbidities and duration of immobilisation prior to onset of ulcer. Methods: This is a prospective study of patients seen within 12 months in the ward or in the surgical outpatient and followed up till discharge or death. Patients were enlisted into the study as they presented. Those with previous surgical treatment of pressure ulcers at the same site were excluded. Results: AGE: range from 15 to 91 years with a mean age of 63.7 years, modal age of 70 years and peak age group 65-79 years (>45 years of age). One patient (10%) was a 15 year old. M: F= 1.2:1. The duration of immobilization prior to development of ulcer ranged from 2 weeks to 20 years. Most of our patients had cerebrovascular disease, 25.8%, as the co-morbidity causing immobilization. Sacral ulcers (61%) were most common site followed by trochanteric (22%). Stage 2 pressure ulcers were the commonest stage.
Income inequality-labor productivity relationship: CS-ARDL approach
Authors: Bağlıtaş Hilal
Published: August 2022

With the acceleration of globalization, “Reducing Inequalities”, which is the 10th of the sustainable development goals, has started to attract more attention in the world. Many factors lead to inequality. Therefore, inequality requires consensus and strength at the interdisciplinary, local, national, and international levels. The leading indicator of inequality is income inequality. Its measurability and widespread impact are sources of its importance and priority. Unfair income distribution might have unfavorable effects on employees such as being more reluctant to work and the well-being of workers. In addition, if workers believe they earn less than they deserve, this might negatively affect the labor productivity. Ultimately, this process may cause countries to reduce their production output.

This study aims to explore the link between income inequality and labor productivity among 31 countries in Europe with the period of 2005-2019. To do this, a cross-sectional auto-regressive distributed lag model (CS-ARDL) is employed. According to the results, wage inequality damages the productivity of labor. A 1% increase in the wage inequality reduces labor productivity by 0.16%. Moreover, the unequal income distribution has an explanatory power of approximately 33% on the decrease in productivity. This helps to determine the possible effects of the unequal income distribution leading towards two targets. These targets are to create an efficient wage structure and eliminate the destructive effects of inequality, respectively. In terms of the policy effectiveness, simultaneous application of tools may be more beneficial.
Dynamics affecting renewable energy: A panel quantile regression approach
Authors: Dayıoğlu Tuğba
Published: August 2022

The effective use of energy resources, energy production and consumption are accepted as one of the most basic indicators of development in recent years. It has become important to use these energy resources in an environmentally friendly manner and have a positive and efficient effect on the economy. The relationship between renewable energy consumption (LREC) and economic factors such as growth rate of GDP per capita (LGDP)), fixed capital investment (LFCI), total labor (LTL), total amount of waste per capita (LWCA) is examined in this study. Data on those variables are collected for the period of 2012-2020 for OECD countries. A panel quantile regression approach method is employed to examine the association between renewable energy consumption (REC) and economic factors. The effects of independent variables on renewable consumption have been interpreted depending on the estimation results obtained in the analysis. Firstly, the panel unit root tests are determined for stationarity. As a result, a panel quantile approach is adopted. The results of the analysis show that all economic variables used in the model have a statistically significant effect on renewable energy consumption in the last two quantiles.
A new variety of Phyllocephalum rangacharii (Gamble) Narayana (Asteraceae) from Kerala, India
Authors: Geethakumary M. , Kumar Ettickal Sukumaran , Pandurangan A.
Published: August 2022

A new variety of Phyllocephalum rangancharii viz. var. agastyamalayanum from Kerala, India is described and illustrated.
Road Mapping Towards a Successful School-Based Management System
Authors: Laranang Jay Ar I
Published: August 2022

This study described the experiences and determined the process and practices of schools with advanced levels in the implementation of School-Based Management (SBM )in Dinalungan and Casiguran District in the Division of Aurora Philippines. The researcher employed the qualitative descriptive method of research where sixteen participants were interviewed, consisting of school heads, teacher coordinators, and community linkages such as the GPTA President and Barangay captain in the same Division. Thematic analysis and document analysis were utilized in generating the emerged five (5) themes, namely, 1. Planning of School-Based Management, 2. Strategizing and Implementing SBM, 3. Struggling the Rough Roads, 4. Transforming leadership, and 5. Achieving excellence at the end of the rocky road. Furthermore, survey participants discussed the school practices they employed to achieve the advanced level. Insights were also presented for the future growth of SBM implementation. The findings revealed that an excellent school’s management would have a significant impact on the quality of instruction provided to the students, the development of schools’ head leadership, the pedagogical skills of teachers, and its vital relationship to the community stakeholders. Based on the findings of this study and the emerged themes, the researcher has drawn the best practices and offered the 5I’s model, which can be utilized to achieve goals that ensure the long-term viability of school-based management. This will be useful for managing programs and projects that benefit both the schools and students by improving the existing practices, implementing the school-based leadership, and maintaining advanced levels in SBM.
Service Compact with All Nigerians (Servicom) and Service Delivery in the Nigerian Public Service: An Appraisal
Authors: Tukur Mustafa Adedeji
Published: August 2022

Over the years, poor service delivery has been identified as one major deficit noted with the Nigerian public service. This has elicited much of intellectual debates and scholarly interventions which have been devoted to underscore the negative perception of poor service delivery in the Nigerian public service. Efforts to change the service delivery orientation of the Nigerian public sector through introducing a new service delivery philosophy have also received some attentions. The SERVICOM Charter, as introduced in March, 2004 becomes the binding document that mandates all government institutions on effective and efficient delivery of services to the Nigerian public. This paper adopted a literature- based approach to underpin the context while, interrogating the need for improved service delivery in the Nigerian public service. Findings from this study argued that, the SERVICOM Charter is challenged by its operational environment as a working document for the reorientation of the Nigerian public service and the citizenry towards effective and efficient service delivery. The paper concluded that, for SERVICOM Charter to achieve the objectives of the changing narratives of poor service delivery in the Nigerian public service, measures are also required for the appropriate compliance of its laudable objectives in the Nigerian public service at large.
La rhinorrhée cérébro-spinale non traumatique révélant une selle turcique vide primitive associée à une HTIC idiopathique : à propos d'un cas et revue de la littérature.
Authors: Essafi Mohammed , Melki Fatima , Aynaou Hayat , Salhi Houda , Ouahabi Hanan
Published: August 2022

La rhinorrhée cérébrospinale spontanée est une maladie rare. Le plus souvent, elle est secondaire aux tumeurs cérébrales ou d’hydrocéphalie, rarement associée à un syndrome de la selle turcique vide.
Nous rapportons l’observation d’une patiente obèse qui a présenté un écoulement nasal gauche. L’exploration avait objectivé une selle turcique vide associée à une hypertension intra-crânienne idiopathique, compliquées de rhinorrhée cérébro-spinale non traumatique par une fuite ethmoïdale (localisation rare). Après traitement par Acetazolamide et des ponctions lombaires itératives, une amélioration clinique et radiologique ont été notées.
Dilated Cardiomyopathy from Immune Checkpoint Inhibitor, Nivolumab
Authors: McCann Timothy , Elabd Hatem , Beerman Stephen
Published: August 2022

Introduction: Nivolumab is an immune checkpoint inhibitor (ICI) in a class of immunomodulators used to treat an array of cancers including melanoma. Here we present ICI related cardiomyopathy leading to patient death.
Caser Report: An 88-year-old female receiving therapy for metastatic melanoma with immune check point inhibitor Nivolumab presented with acute hypoxic respiratory failure secondary to new onset acute combined systolic and diastolic heart failure. She had no known cardiac history and was on minimal medication prior to presentation. After extensive work-up including pleural fluid analysis, a cardiac magnetic resonance, and left heart catheterization, no other cause could be attributed to her cardiac dysfunction other than medication adverse event due to immunomodulation therapy with Nivolumab.
Discussion: Cardiomyopathy is a rare, but potentially life-threatening complication of ICI therapy and should be considered when discussing treatment modalities with patients, especially in high-risk populations.
Aprendizajes en la enseñanza remota de emergencia para pensar la educación en la pospandemia
Authors: Macchiarola Viviana , Pizzolitto Ana Lucía , Pugliese Verónica Lucía
Published: August 2022

El artículo se ubica en el campo del planeamiento institucional y vincula la idea de calidad con los conceptos de innovación y derecho a la educación. Se presentan parte de resultados de una investigación realizada durante el año 2020 en la Universidad Nacional de Río Cuarto (UNRC), cuyo objetivo general fue analizar, desde una perspectiva de reconocimiento de derechos, dinámicas emergentes de la enseñanza universitaria durante la pandemia asociada al COVID-19. Se realizó una investigación con enfoque multimétodo que consta de tres estudios vinculados y orientados hacia los siguientes objetivos específicos: a) establecer relaciones entre las condiciones socioeconómicas de los estudiantes y sus posibilidades de acceso material y práctico a las tecnologías; b) reconocer, desde la perspectiva de los docentes, las prácticas, condiciones y valoraciones de la enseñanza remota de emergencia; c) identificar los impactos pedagógicos de la enseñanza remota desde la perspectiva de los estudiantes. Se identifican potenciales innovaciones y límites de la incorporación de las tecnologías a la enseñanza, ofreciendo tres categorías temáticas emergentes que permitirían comprender e interpretar otros casos: 1) procesos de inclusión-exclusión; 2) modificación de los tiempos y espacios de aprendizaje, 3) cambios en prácticas docentes.
Descolonizar a universidade: Uma experiência no horizonte da integração latino-americana
Authors: Herz Genro Maria Elly , Castro Gusmão Renata , Tomazzoni Marcarini Camila , Mello Fernandes Victória , Dal Farra Rossana , Garcia Machado Jurema , Silveira Carlos Alessandro
Published: August 2022

Este artigo tem como objetivo compartilhar resultados da pesquisa Universidade, Formação Política e Bem Viver: Estudo dos Projetos de Universidades Emergentes no Brasil (2003-2014), uma pesquisa qualitativa, construída coletivamente, envolvendo docentes e discentes de graduação e pós-graduação. Envolve quatro universidades emergentes: Universidade Federal da Integração Latino Americana (UNILA); Universidade Federal do Sul da Bahia; Universidade Federal da Fronteira Sul e Universidade Federal do Pampa. Compartilhamos aqui os achados relacionados a UNILA - uma experiência que promove movimentos de descolonização da universidade e do processo formativo. Direcionamos o foco às novas gramáticas, uma das ideias forças que surgiram da análise das entrevistas. Trazemos fragmentos das vozes como narrativas do momento, percorremos documentos oficiais e um referencial teórico objetivando ampliar e atualizar a proposta de integração diante do contexto atual. Consideramos como novas gramáticas: brechas descoloniais que contribuem com a ousada proposta de integração latino-americana, uma Ecologia de Saberes (Santos, 2019) em desdobramentos, articulando interculturalidade e interdisciplinaridade, em conexão com o bilinguismo. Uma proposta desafiadora que precisa ser fortalecida e atualizada constantemente, almejando uma formação política em direção ao Bem Viver (Eschenhagen, 2013) como caminho possível e necessário em direção à qualidade social.
Estudiantes bolivianos de posgrado en el Programa “Becas Brasil” PAEC-OEA – GCUB 2011-2021
Authors: Orellano Narvaez Sergio Mario
Published: August 2022

Este trabajo tuvo como propósito observar, describir e interpretar algunas de las principales características de la participación de estudiantes bolivianos en el programa Becas Brasil PAEC-OEA - GCUB (2011-2021) que concediera becas de maestría y doctorado. A partir del análisis y sistematización de información contenida en varias fuentes documentales sobre sus procedencias institucionales, trayectorias individuales en el programa y áreas de conocimiento, con una estrategia empírica-inductiva, experimentando con base en estos resultados, pensar posteriormente algunas conclusiones genéricas o hipótesis para interpretar los posibles efectos de este programa en la formación académica de posgrado de profesionales bolivianos en el exterior y en la producción del conocimiento local en Bolivia, que puedan ser testadas en futuros trabajos de investigación. En este horizonte, se constató que los estudiantes han devenido mayoritariamente de las universidades públicas más grandes y con mayor prestigio. Asimismo, varios de ellos han continuado su formación de posgrado, transitando de la maestría al doctorado en Brasil dentro y fuera del programa Becas Brasil. Por último, se hace necesario resaltar que las principales áreas de conocimiento en las que se formaron los estudiantes corresponden principalmente a las Ciencias de la Computación y la Ecología, seguidas de un segundo conglomerado en torno a la Física, Química, Geo ciencias, Genética, Ingeniería Civil, Odontología y Medicina. Se sugieren nuevas pesquisas complementarias sobre la preponderancia de temáticas disciplinares, teorías y metodologías según área de conocimiento. Así como también sobre las trayectorias académicas y profesionales posteriores al retorno de los estudiantes a su país de origen.
The Third Wave of Technology in Education
Authors: Rodriguez Juan Pedro
Published: August 2022

Some of the criteria that are set out below may guide you to a reflection about how should be define the next curriculums and profiles of the teachers in the context of the development of these technologies. The interest that animates this essay deals with a conceptual appreciation of how we imagine and understand the bond and the structure of the relationship that occur between new technologies and education. This interest deals with a conceptual appreciation of how we imagine and understand the bond and the structure of the relationship that occur between new technologies and education. Within the context of the changing social composition of the relationship between education and human growth and quality of life, there is an obvious requirement for the school to become more in tune with contemporary tendencies in information technology and communication.
Feministiska interventioner
Authors: Lövkrona Inger
Published: August 2022

Den akademiska kulturen har länge kännetecknats av en vertikal könssegregering – ju högre upp i hierarkin desto fler män. Statsmakterna har sedan decennier försökt komma till rätta med akademins brist på jämställdhet inom ramen för den nationella jämställdhetspolitiken. I denna artikel diskuteras de senaste decenniernas politiska satsningar för att uppnå jämställdhet i det seniora ledarskapet i akademin. Vilka strategier och åtgärder har implementerats och vilka effekter har de haft? Jag tar min utgångspunkt i svensk och internationell forskning om jämställdhetsinsatser för att locka fler kvinnor in i akademiskt ledarskap, samt i egna erfarenheter från ett genusintegrerat ledarutvecklingsprogram för blivande dekaner vid Lunds universitet. Avslutningsvis argumenterar jag för en feministisk intervention – ett genusmedvetet ”nomadiskt” ledarskap – som en möjlig väg till förändring. Förhåller det sig så att feministiska interventioner, inte jämställdhetssatsningar, måste till för att förändring ska åstadkommas?
STAPHYLOCOCCUS AUREUS SUŞLARINDA NİKLOZAMİDİN MUPİROSİN İLE IN VİTRO SİNERJİSTİK ETKİSİNİN TARAMA TESTİ İLE ARAŞTIRILMASI
Authors: CİHAN Merve , KAYGUSUZ Arif
Published: August 2022

Staphylococcus aureus taşıyıcılarında kullanılan antibiyotiklere direncin artması alternatif tedavi arayışını gündeme getirmiştir. Bu araştırma ile S. aureus izolatlarında niklozamidin mupirosin ile in vitro sinerjistik etkisinin olup olmadığının incelenmesi hedeflenmiştir.
2021 yılında laboratuvarımıza gönderilen örneklerden 25 metisiline duyarlı S. aureus (MSSA) ve 25 metisiline dirençli S. aureus (MRSA) izolatı toplanmıştır. İzolatlarda çift disk sinerji yöntemi uygulanarak niklozamid ile mupirosin arasında in vitro sinerjistik etki olup olmadığı incelenmiştir.
Çalışmada test edilen izolatlarda iki antimikrobiyal ilaç arasında herhangi bir sinerji saptanmamıştır. İzolatların sadece MRSA grubundaki iki tanesinde mupirosine direnç gözlenmiş olup, diğer izolatların tümünün mupirosine duyarlı olduğu bulunmuştur.
S. aureus izolatlarında niklozamidin mupirosin ile in vitro sinerjistik etkisinin olmadığı gözlenmiştir.
Gelam Honey Inhibition of Bacterial Pathogen: Determination of MIC and NIC Values Using the Lambert-Pearson Model
Authors: Ismail Ahmad Syazwan , Shukor Mohd Yunus , Masdor Noor Azlina
Published: August 2022

The curative effect of honey is due to the fact that it possesses antibacterial activity, it keeps wounds moist by retaining their natural moisture, and the honey's high viscosity contributes to the formation of a protective barrier that helps to keep infections at bay. All of these properties work together to make honey an effective wound healer. In addition, the immunomodulatory action that it possesses plays a part in the process of wounds healing. Honey's antibacterial efficacy against bacterial pathogens is frequently indicated by the lowest minimum inhibitory concentration (MIC) and the non-inhibitory concentration (NIC) values. The reality that all of the MIC and NIC techniques that are now being used are just semi-quantitative in nature is the primary issue that develops as a consequence of this circumstance. Use of data-driven nonlinear regression analysis as one of the ways to determine this value is one of the methods that has the highest degree of precision out of all of the methods that may be used. Using the Lambert-Pearson modified Gompertz model, it was feasible to successfully determine the MIC and NIC of the gelam honey against different bacterial pathogen remodels. According to the Shukor's chart for MIC values, S. aureus is the pathogen most sensitive to gelam honey followed by E. coli and P. aeruginosa while the MIC value for B. cereus overlaps with P. aeruginosa indicating that more research is required to determine where B. cereus falls in terms of sensitivity. There is a good match between the data and the Lambert-Pearson model, with values for the coefficient of determination (R2) ranging from 0.94 to 0.97. Based on these findings, it appears that honey from gelam trees has the potential to inhibit the formation of bacterial infections.
Isolation and Identification of Fungi Associated with Rot of Cucumber (Cucumis sativus L.) In Jimeta, Yola North Local Government Area, Adamawa State
Authors: Jimeta Zubairu Gaddafi , Kiri Audu Sanusi , Gambo Zakari Bawa , Sakiyo David Cromwell
Published: August 2022

Cucumber fruit (Cucumis sativus L.) is believed to have originated from Southern Asia and fourth most important vegetable after tomato, cabbage and onion. The objective is to isolate and identify fungi responsible for rot of cucumber (Cucumis sativus L.) in the study area. Potato dextrose agar was used as growth medium. Three fungal pathogens (Aspergillus flavus, Rhizopus stolonifer and Aspergillus brasiliensis) were identified through pathogenicity test to be causing rot of Cucumber fruit in Jimeta markets (Gwari Market, Jimeta Modern Market and Jimeta Shopping Complex Market), Yola North of Adamawa state. Isolation and identification of pathogens responsible for cucumber fruit rot in Jimeta Markets were carried out, where Rhizopus stolonifera had the highest (25-48%) frequency of occurrence while Aspergillus flavus was the least (22-38%). From the study, it is concluded that Aspergillus brasiliensis, Rhizopus stolonifer and Aspergillus flavus were found out to be the fungal pathogen that caused rot of Cucumber (Cucumis sativus L.) fruit in the study area. The vulnerability of Cucumber fruit to fungal rot is not far from the poor way and manner at which the fruits are conveyed, stored and traded in the study area. It is recommended to farmers and fruit vendors to be conveying perishable fruits in soft bags and stored in cool dry places.
Woody Species Composition and Diversity of Wawa-Zange Forest, Gombe State, Nigeria
Authors: Abba H.M. , Yuguda U.A. , Yila C.N. , Zhigila A.D.
Published: August 2022

According to recent research, severe human-induced deforestation is causing 65 percent of the thirty Forest Reserves spread over Gombe State to progressively transform into the desert. The research was done in the Wawa-Zange Forest Reserve in Gombe State, Nigeria, to assess the richness of woody species and biodiversity preservation. The vegetation was sampled with the Point Centered Quarter technique. A complete enumeration of Woody (Trees and Shrubs) with (Diameter at Breast Height or DBH) ≥10 and ≥5cm was carried out. Using Simpson's Diversity and the Shannon-Wiener index, alpha diversity was evaluated. A total of 51 woody species from 16 families and 41 genera were discovered. 34 were trees while 17 were shrubs. Most species were found in the Fabaceae family. Ceasalpinoidae (10), Mimosoideae (4), Papilionoideae (3), Combretaceae (7), Rubiaceae (5), Anacardiaceae, Burseraceae, Capparaceae , Moraceae, Tiliaceae had two species each. The other families are namely Apocynaceae, Ebanaceae, Loganiaceae, Meliaceae, Rhamnaceae, Sapotaceae, Zygophyllaceae with one species each. Simpson index of Diversity was (0.55) and the Shannon-Wiener index was (2.07). This study concluded that plants with low Importance Value Index or IVI such as Pterocarpus erinaceous, Capparis mitchelli, and Pericopsis laxiflora need urgent conservation measures. Therefore, it is important to properly adopt conservation and sustainable management measures.
Vegetation Structure and Diversity in Northern Yobe, Nigeria
Authors: Bukar Sani Mai , Abba Halima Mohammed
Published: August 2022

The study examined the diversity of vegetation (tree species and shrubs) for the preservation, utilization and conservation of tree species in Northern Yobe. A point centred quarter (PCQ) method was employed to study the vegetation structure in six randomly selected experimental sites across the three local government councils in Northern Yobe (Yunusari, Yusufari and Geidam). A total of 22 tree species and 7 shrubs belonging to 15 families were identified, with Fabaceae being the family with the highest number of tree species (5 members), and followed by Combretaceae, Mimosaceae, and Rhamnaceae each with 3 members. Aracaceae, Euphorbiaceae, Rhamnaceae, and Moraceae have 2 members each, while other identified families had a member of tree species. Specifically, Sodom apple was the dominant tree species based on Importance Value Indices (IVI) of 23.3, followed by Doum palm (22.0), then Guiera tree and Combretum species, each with IVI of 20.7, followed by Desert date (20.3), Thorn Acacia (19.9), and then Whistling thorn (19.3 as their IVI. The Diversity index was determined as 1, Simpson’s index of diversity was very low (-0.0082) and the species richness was 0.41. The low values indicate a less complex community, and the distribution pattern of the various parameters assesses was that of a typical Sahel-Savannah vegetation. Nevertheless, there was a large number of different tree species (29) recorded which implies many tree species are adaptable in the study area but only regenerated naturally without effort for intensive production. Therefore, the need of mass production of these trees in plantation and agroforestry for the conservation and utilization of the dominant (most adapted) tree species to halt environmental associated problems including desertification and erosion in the study area.
Effects of Refining and Petrochemical Effluents on Water Quality and Zooplankton Community in River Rido Kaduna, Nigeria
Authors: Dauda D.M. , Emere M.C. , Umar Y. , Umar A.M.
Published: August 2022

Kaduna Refining and Petrochemical Corporations (KRPC) discharges were studied for a year along the river Rido to determine their impact on water quality and the distribution and abundance of Zooplankton. Physical and chemical parameters were measured following American Public Health Association (APHA) standards for evaluating wastewater. An atomic absorption spectrometer (AAS) was utilized for heavy metal analysis. For this experiment, we used a Plankton net with a 25 m mesh size and a specimen bottle with a 10 cm diameter ring opening to collect zooplankton. Zooplanktons were identified using a standard key and a monograph. Water quality parameters fluctuated, but all were within acceptable ranges except for temperature, conductivity, Total Dissolved Solid, and lead. Zooplanktons were represented in order of abundance by 8 species of protozoa constituting 72.44%, followed by 12 species of Rotifera (10.58%), followed by 13 species of Cladocera 9.55% and then 6 species of Copepoda (7.44%). The planktons showed seasonal variation with high density recorded during the wet season in all the stations. There was a low density of zooplankton in station B, while high density was observed in stations A and D. Also, the low transparency and dissolved oxygen (DO) as well as high mean values of temperature (30.88 oC), chloride (31.88 mg/L), lead (0.099 mg/L), TDS (224.17 mg/L) and conductivity (334.28 µS/cm) observed were above FEPA limits at station B were an indication of pollution and deterioration of water quality. This research revealed that the effluent discharge from KRPC has adverse effects on the zooplankton community and the water quality of river Rido.