bluuebunny/crossref_metadata_2025 huggingface dataset:
Psalm 72 in light of the psychological theories of poverty
Authors: Mtshiselwa Ndikho
Published: October 2024

Prior to the 1980s, various theories of poverty have been proposed by psychologists, ranging from, but not limited to, ‘naturalizing perspective’, ‘constitutionally inferior perspective’, or ‘nativist perspective’; to the ‘McClelland approach’ (McClelland 1961, 1965, 1973); to the ‘attribution theory’; and to Lewis’ (1975) culture of poverty theory. The theories tease out issues of the accumulated environmental deficits and psychiatric disorders, such as depression as well as the lack of ambition and mental drive to achieve success. However, from the 1980s, psychologists returned to the Lewis’ culture of poverty theory. The World Bank Development Report for 2000–2001’s expansion of Sen’s (1999) theory, which placed emphasis and/as three-pillars on ‘security’, ‘empowerment’ and ‘opportunity’ led for one, among other psychological bodies, the American Psychological Association to consider various conceptualisation of the theories of poverty. The paper tests the psychological theories of poverty against the background of the historical-literary read poetic text of Psalm 72. Does a poetic reading of Psalm 72 bear a psychological meaning when read within the framework of psychological theories of poverty? Firstly, the paper investigates psychological theories of poverty prior to 1980s to the present. Secondly, in a poetically and historically read Psalm 72, the psychological presuppositions are teased out. In the end, the paper submits with caution that when read within the framework of psychological theories of poverty, the poetically read Psalm 72 produces psychological meaning, which contributes value to the reading of Biblical poetic texts.Intradisciplinary and/or interdisciplinary implications: The article draws on the discipline of psychology, employing the psychology theories of poverty to read an Old Testament poetic text of Psalm 72. The meaning of Psalm 72 is derived from the psychological reading of the historical-literary critically analysed poetic Hebrew Bible text.
Impact of yoga and naturopathy on stress, anxiety, heart rate variability, and quality of life of a patient with social anxiety disorder
Authors: Vijay A. , Nivethitha L. , Arunthathi R. , Mooventhan A.
Published: October 2024

A 32-year-old male diagnosed with social anxiety disorder (SAD) visited our hospital with complaints of avoiding social events due to fear of negative judgment, difficulty in conveying thoughts, embarrassment, and overthinking. He also struggled to initiate conversations and experienced agoraphobia, which made him feel anxious in crowded places. He underwent a 23-day comprehensive yoga and naturopathy intervention. Compared to the baseline, the postintervention assessment showed a reduction in Perceived Stress Scale score and Hamilton Anxiety Rating scores and improvement in heart rate variability (HRV) and Short Form (SF)-36 healthy survey. It suggests that yoga and naturopathy might be beneficial in decreasing stress and anxiety and in enhancing HRV and quality of life of people with SAD. However, as this is a single case report, more studies are recommended to validate the findings of this study.
Nasal dermoid cyst
Authors: Samantaray Kabikanta , Acharya Sneha , Mallick Manisha , Senapati Sweta , Rishi Kanav
Published: October 2024

Congenital midline lesions of the nose include nasal dermoids, encephaloceles, and gliomas. The nasal dermoid is least rare of these and is an uncommon midline developmental anomaly. Unlike encephalocoeles and gliomas ,craniofacial dermoids may present as a cyst, a sinus or a fistula (Setiyawan, 2013). In this patient, it was a cystic nasal swelling obscuring vision without any problem in visual acuity. He had this lesion from childhood but presented to the outpatient department in adolescent age. Diagnostic nasal endoscopy, ultrasonography, fin- needle aspiration cytology, and contrast-enhanced computed tomography of the nose and paranasal sinuses were done reporting it as a nasal dermoid without any bony erosions. All routine investigations were done, and the patient was planned for excision under general anesthesia (GA). Excision of the mass was done under GA and sent for histopathology. Histopathological examination report confirmed it as a dermoid cyst.
Integrative medicine: Scope for yoga and naturopathy to take center stage among the AYUSH streams
Authors: Srilakshmi M. Priya , Mooventhan A. , Nivethitha L.
Published: October 2024

Integrative medicine incorporates both conventional and complementary health care approaches. With increased awareness among people about AYUSH system of medicine and increased effort in wellness in form of Yoga, the question of interest is about yoga and naturopathy to become a major treatment modality in AYUSH stream.
Clinical and experimental methods for sexual identification of mandibular canines in ethnic Himachali population: A comparative analysis
Authors: Negi Brijesh Kumar , Prasad R. Guru , Gurung Deepak
Published: October 2024

Background:

Sex assessment plays a vital role in creating the physical profile of a deceased person, along with considerations of race, stature, and age. Canine teeth are particularly significant in human evolution, as they are frequently among the few dental remains found in fossils and allow them to endure extreme conditions.

Aim:

The aim of the study was to assess mandibular canines in determining gender among the Himachali population, with a comparative analysis of odontometric measurements.

Methods:

The study involved 102 participants from an ethnically diverse Himachali population, consisting of 51 males and 51 females, aged between 17 and 25 years, who visited the oral medicine and radiology department at a tertiary care facility. Intraoral measurement of the right and left mandibular canine and intercanine widths was recorded using a Vernier caliper. An alginate impression of the mandibular arches was replicated in study models with dental stones for further analysis.

Results:

The mean difference between mandibular right and left canine width and intercanine distance in Himachali males and females both intraorally and on casts was statistically nonsignificant. The mean value of the right and left canine and intercanine widths was comparable intraorally and on casts in Himachali males and females.

Conclusion:

This study suggests mandibular canine measurement as a supplementary and dependable method for sexual identification in humans.
Lithium’s renaissance: From psychiatric staple to multifaceted medical marvel
Authors: Ravan Jayaprakash Russell , Pattnaik Jigyansa Ipsita , Panda Udit Kumar , Samantaray Swayanka , Mishra Bhumika
Published: October 2024

Lithium, long established as a cornerstone in the treatment of bipolar disorder, has recently emerged as a potential therapeutic agent across a broad spectrum of medical fields. This narrative review examines the expanding role of lithium in contemporary medicine, highlighting its transition from a psychiatric staple to a versatile therapeutic tool. The objective of the study was to synthesize and critically evaluate recent literature on lithium’s applications beyond psychiatry, focusing on its mechanisms of action, therapeutic potential, and challenges in various medical domains. A comprehensive literature search was conducted using PubMed, Scopus, and Web of Science databases, focusing on peer-reviewed articles published within the last 5 years. Keywords included “lithium” combined with terms such as “neuroprotection,” “cancer,” “stem cells,” “viral infections,” and “aging.” Case studies, clinical trials, systematic reviews, and meta-analyses were included to provide a broad perspective on lithium’s emerging roles. Recent studies have revealed lithium’s potential in several key areas: neuroprotection in neurodegenerative disorders, cancer therapy enhancement, stem cell mobilization for regenerative medicine, antiviral properties, cardioprotection against ischemia-reperfusion injury, circadian rhythm regulation, and potential effects on longevity and healthy aging. Lithium’s renaissance in medical research reveals its potential as a multifaceted therapeutic agent. While challenges remain, including its narrow therapeutic index and side effect profile, ongoing research into novel delivery methods and personalized medicine approaches may optimize its use. The expanding applications of lithium underscore the need for continued investigation to fully harness its therapeutic potential across various medical disciplines.
Histopathological Profile of Cholecystectomy Specimens at a Tertiary Care Center: A Retrospective Study
Authors: Bajaj Udita , Kalsi Dimple , Bajaj Preeti , Chikhalikar Sheela
Published: October 2024

Introduction:

Gallbladder is one of the most frequently received specimens in any histopathology laboratory. Its diseases may present with a varied spectrum ranging from congenital anomalies, cholelithiasis, and inflammatory or noninflammatory lesions to noninvasive and invasive neoplasms. Cholelithiasis (gallstones) is the most common lesion and accounts for more than 95% of gallbladder diseases and affects 10%–20% of the adult population. The incidence is 2–4 times higher in females than in males.

Aims and Objectives:

This study was designed to study the histopathological spectrum of gall bladder diseases in the population, study the most common gall bladder diseases in cholecystectomy specimens, and study the frequency of gall bladder carcinoma.

Methodology:

This retrospective observational study was done in the Pathology department at a tertiary care hospital and research center, from September 2016 to September 2023. Tissue was fixed in 10% buffered formalin and then processed by the routine paraffin embedding techniques. Sections were cut at 4–5 μ thickness and stained with hematoxylin and eosin stains. Special stains were done if required for confirmation. All the slides were analyzed and reported by a trained histopathologist.

Results:

Females were affected more as compared to males. The commonest age group affected was 41-50 years. Gallstones were observed in 33.58% of patients. Gallbladder neoplasm was rare and incidental findings.

Conclusion:

Gallbladder disease demonstrated a diverse spectrum of histopathological changes in the cholecystectomy specimens and showed female preponderance. Gallbladder carcinoma was observed as a rare occurrence and was an incidental finding mainly. Hence, a microscopic (histopathological) examination is required for every cholecystectomy specimen.
Biliary microbiome and gallstones: A silent friendship
Authors: Banerjee Tuhina , Goswami Aakansha Giri , Basu Somprakas
Published: October 2024

With increasing evidence, the biliary tract and the gallbladder mucosa are no longer considered sterile environments devoid of bacteria. Rather a profound biofilm of resident bacterial flora is associated with the mucosal surface. The bile too harbors a resident flora. It is when a dysbiotic process ensues, that this bacterial flora either becomes opportunist or is replaced by a pathogenic one that has a strong ability to survive the challenges of the biliary environment. Although once believed a metabolic problem, recent evidence indicates a complex interaction between different species of bacteria and gallbladder mucosa and bile which may culminate in calculus formation. The resident microbiota and its several enzymes dictate the type of gallstone by the mere interplay of the constituting type of bacteria in the biofilm, even without any evidence of infection. Dysbiosis is often mediated by either intestinal dysbiosis or less probably by oral dysbiosis. The gallstones, in turn, provide a haven for the resident microbiota in which they can form their own defined niche enriched with the biofilm that can resist the biliary defense mechanisms and survive the hostile biliary environment in the background of biliary stasis and local infection. However, this process of silent friendship is more complex than said, and further research is needed to define the relationship between the two.
Benefits and drawbacks of radiofrequency ablation via percutaneous or minimally invasive surgery for treating hepatocellular carcinoma
Authors: Hsieh Ching-Lung , Peng Cheng-Ming , Chen Chun-Wen , Liu Chang-Hsien , Teng Chih-Tao , Liu Yi-Jui
Published: October 2024

The management of early stage hepatocellular carcinoma (HCC) presents significant challenges. While radiofrequency ablation (RFA) has shown safety and effectiveness in treating HCC, with lower mortality rates and shorter hospital stays, its high recurrence rate remains a significant impediment. Consequently, achieving improved survival solely through RFA is challenging, particularly in retrospective studies with inherent biases. Ultrasound is commonly used for guiding percutaneous RFA, but its low contrast can lead to missed tumors and the risk of HCC recurrence. To enhance the efficiency of ultrasound-guided percutaneous RFA, various techniques such as artificial ascites and contrast-enhanced ultrasound have been developed to facilitate complete tumor ablation. Minimally invasive surgery (MIS) offers advantages over open surgery and has gained traction in various surgical fields. Recent studies suggest that laparoscopic intraoperative RFA (IORFA) may be more effective than percutaneous RFA in terms of survival for HCC patients unsuitable for surgery, highlighting its significance. Therefore, combining MIS-IORFA with these enhanced percutaneous RFA techniques may hold greater significance for HCC treatment using the MIS-IORFA approach. This article reviews liver resection and RFA in HCC treatment, comparing their merits and proposing a trajectory involving their combination in future therapy.
Immunotherapy for metastatic gastric cancer
Authors: Li Chang-Fei , Lian Li-Li , Li Qiu-Ru , Jiao Yan
Published: October 2024

This editorial discusses the article written by Chen et al that was published in the latest edition of the World Journal of Gastrointestinal Surgery . The current study found that programmed cell death 1 ligand 1 (PD-L1) expression is considered as one of the pan-cancer biomarkers of immune checkpoint inhibitors (ICIs) treatment response. Four molecular subtypes are widely used to guide and evaluate the prognosis and diagnosis and treatment of gastric cancer (GC) patients. Clinical trials of ICI treatment including Nivolumab, Pembrolizumab, Avelumab have been conducted for metastatic GC (mGC). The effects of various single agent ICIs on mGC therapy varied. ICIs combined with chemotherapy can indeed bring survival benefits to patients with mGC. Combining ICIs with chemotherapy can give more patients the chance of surgery in the treatment of GC transformation. However, not all PD-L1 positive patients can benefit from it. It is urgent to find better biomarkers to predict the response of ICIs for more precise clinical treatment.
Clinical study of different interventional treatments for primary hepatocellular carcinoma based on propensity-score matching
Authors: Cheng Xiao-Bo , Yang Li , Lu Ming-Qian , Peng Yi-Bo , Wang Lei , Zhu Shuang-Ming , Hu Zhi-Wei , Wang Zhong-Liang , Yang Qin
Published: October 2024

BACKGROUND

Transcatheter arterial chemoembolization (TACE) is the main treatment for patients with primary hepatocellular carcinoma (PHC) who miss the opportunity to undergo surgery. Conventional TACE (c-TACE) uses iodized oil as an embolic agent, which is easily washed by blood and affects its efficacy. Drug-eluting bead TACE (DEB-TACE) can sustainably release chemotherapeutic drugs and has a long embolization time. However, the clinical characteristics of patients before the two types of interventional therapies may differ, possibly affecting the conclusion. Only a few studies have compared these two interventions using propensity-score matching (PSM).

AIM

To analyze the clinical effects of DEB-TACE and c-TACE on patients with PHC based on PSM.

METHODS

Patients with PHC admitted to Dangyang People’s Hospital (March 2020 to March 2024) were retrospectively enrolled and categorized into groups A (DEB-TACE, n = 125) and B (c-TACE, n = 106). Sex, age, Child-Pugh grade, tumor-node-metastasis stage, and Eastern Cooperative Oncology Group score were selected for 1:1 PSM. Eighty-six patients each were included post-matching. Clinical efficacy, liver function indices (aspartate aminotransferase, alanine aminotransferase, total bilirubin, and albumin), tumor serum markers, and adverse reactions were compared between the groups.

RESULTS

The objective response and disease control rates were significantly higher in group A (80.23% and 97.67%, respectively) than in group B (60.47% and 87.21%, respectively) (P < 0.05). Post-treatment levels of aspartate aminotransferase, alanine aminotransferase, and total bilirubin were lower in group A than in group B (P < 0.05), whereas post-treatment levels of albumin in group A were comparable to those in group B (P > 0.05). Post-treatment levels of tumor serum markers were significantly lower in group A than in group B (P < 0.05). Patients in groups A and B had mild-to-moderate fever and vomiting symptoms, which improved with conservative treatment. The total incidence of adverse reactions was significantly higher in group B (22.09%) than in group A (6.97%) (P < 0.05).

CONCLUSION

DEB-TACE has obvious therapeutic effects on patients with PHC. It can improve liver function indices and tumor markers of patients without increasing the rate of liver toxicity or adverse reactions.
Laparoscopic cholecystectomy plus common bile duct exploration for extrahepatic bile duct stones and postoperative recurrence-associated risk factors
Authors: Liao Jia-Hua , Li Ju-Shi , Wang Tie-Long , Liu Wen-Shen
Published: October 2024

BACKGROUND

There remain controversies regarding the surgical treatment of extrahepatic bile duct stones (EHBDSs) in clinical practice.

AIM

To explore the curative effect of laparoscopic cholecystectomy (LC) plus common bile duct exploration (CBDE) for the surgical treatment of EHBDSs and to analyze the risk factors that affect postoperative stone recurrence.

METHODS

Eighty-two patients with EHBDSs admitted between March 2017 and March 2023 were selected. Among them, patients treated with open choledocholithotomy plus LC or open cholecystectomy (OC) were set as the control group (n = 40), and those treated with LC plus CBDE served as the observation group (n = 42). The surgical outcomes of the two groups were compared, the surgical complications and Gastrointestinal Quality of Life Index (GIQLI) scores were counted, and the one-year prognostic recurrence was recorded. Independent factors for postoperative recurrence were determined using univariate and multivariate analyses.

RESULTS

The two groups were comparable in the stone residual rate (P > 0.05). The operation time (P < 0.05), intraoperative bleeding (P < 0.05), and total complication rate (P = 0.005) were lower in the observation group than in the control group. The observation group exhibited a marked increase in the GIQLI score, which was higher than the control group (P < 0.05). A lower one-year recurrence rate was determined in the observation group vs the control group (P = 0.027). Sphincter of Oddi dysfunction [odds ratio (OR) = 5.712, P = 0.007] and the treatment scheme of open choledocholithotomy plus LC or OC (OR = 6.771, P = 0.008) were the independent risk factors for one-year recurrence in patients after surgery.

CONCLUSION

LC plus CBDE for patients with EHBDSs can reduce stone residuals, intraoperative bleeding, complications, and postoperative recurrence.
Meta-analysis of electrical stimulation promoting recovery of gastrointestinal function after gynecological abdominal surgery
Authors: Huang Xue-Xia , Gu Hui-Feng , Shen Ping-Hua , Chu Bo-Liang , Chen Ying
Published: October 2024

BACKGROUND

The effects of electrical stimulation on gastrointestinal function recovery after gynecological abdominal surgery was not clear.

AIM

To systematically evaluate the effects of electrical stimulation on gastrointestinal function recovery after gynecological abdominal surgery.

METHODS

The Cochrane Library, Web of Science, PubMed, ProQuest, and the Chinese biomedical literature databases Wanfang, Weipu, and CNKI were used to search for relevant studies on controlled trials of electrical stimulation in gynecological abdominal surgery patients from self-established databases to May 2024. The RevMan software (version 5.3) was used to analyze the included literature and explore the heterogeneity of each study.

RESULTS

Seven controlled trials, involving 520 patients, were included. The results of meta-analysis showed that electrical stimulation could shorten the recovery time of intestinal sound after gynecological abdominal surgery [odds ratio (OR): -5.11, 95%CI: -5.84 to -4.38, P < 0.00001] and improve the time of first anal exhaust (OR: -1.19, 95%CI: -1.38 to -0.99, P < 0.00001), improved the time of first anal defecation (OR: -0.98, 95%CI: -1.19 to -0.78, P < 0.00001), The difference is significant. According to the funnel plot, if the scatter is symmetrical, it indicates that the funnel plot is unbiased.

CONCLUSION

Electrical stimulation can shorten this reduces the length of time it takes for the patient to recover from bowel sounds and also affects the time to first anal voiding and defecation to some extent, thereby promoting gastrointestinal function recovery after gynecological abdominal surgery. The quality of the studies included in this review was poor, which may have affected the final results. It is necessary to conduct a randomized controlled study with higher quality and more samples to further confirm the promoting effect of electrical stimulation on gastrointestinal function recovery to guide clinical treatment.
Outcome and risk factors of ulcer healing after gastric endoscopic submucosal dissection: A systematic review and meta-analysis
Authors: Chen De-Yi , Chen Hai-Dong , Lv Xiao-Dan , Huang Zhou , Jiang Dan , Li Yu , Han Bing , Han Li-Chun , Xu Xiao-Fang , Li Shi-Quan , Lin Guang-Fu , Huang Zhi-Xi , Lin Jia-Ning , Lv Xiao-Ping
Published: October 2024

BACKGROUND

Endoscopic submucosal dissection (ESD) is widely utilized for the treatment of large adenomas, submucosal lesions, and early gastric cancer. A significant artificial ulcer typically forms after ESD. Delayed or incomplete healing of these ulcers can result in complications such as delayed bleeding and perforation. However, a comprehensive review of the outcomes and risk factors related to ulcer healing following ESD is currently lacking.

AIM

To assess ulcer healing outcomes and identify risk factors associated with delayed ulcer healing.

METHODS

Databases retrieved by computer include PubMed, EMBASE, The Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wan Fang Data, and VIP. The study collects reports on ESD post-surgical ulcer healing outcomes and risk factors, using Stata 16.0 and RevMan 5.0 software for meta-analysis.

RESULTS

Our analysis included 12 studies, involving a total of 3430 patients. The meta-analysis revealed an overall healing rate of 65.55% for ulcers following ESD [odds ratio (OR) = 2.71; 95% confidence interval (CI): 2.45-3.00]. The healing rate within eight weeks was 48.32% (OR = 0.76; 95%CI: 0.35-1.66), while the rate beyond eight weeks was 88.32% (OR = 6.73; 95%CI: 3.82-11.87). Risk factors included Helicobacter pylori (H. pylori ) infection (OR: = 5.32; 95%CI: 1.90-14.87; P = 0.001), ulcer size (OR = 2.08; 95%CI: 1.19-3.61; P = 0.01), lesion site (OR = 2.08; 95%CI: 1.19-3.11), and pathological type (OR = 1.64; 95%CI: 1.06-2.52). Diabetes (OR = 0.56; 95%CI: 0.05-5.80; P = 0.63) and duration of operation (OR = 1.00; 95%CI: 0.99-1.01; P = 0.96) were not significant factors.

CONCLUSION

The healing rate of ulcers following ESD is high after eight weeks. Risk factors affecting the healing process include H. pylori infection, ulcer size, lesion site, and pathological type.
Therapeutic endoscopic retrograde cholangiopancreatography in a patient with asplenia-type heterotaxy syndrome: A case report
Authors: Zhang Yu-Yan , Ruan Jiang , Fu Yan
Published: October 2024

BACKGROUND

Asplenia-type heterotaxy syndrome (HS) is rare and refers to visceral malposition and dysmorphism. It is associated with a high infant mortality rate due to cardiac anomalies, and related digestive endoscopic interventions are poorly understood. With the improved long-term prognosis of these individuals after modern cardiac surgery, intra-abdominal anomalies have become increasingly significant.

CASE SUMMARY

Herein, we report successful endoscopic retrograde cholangiopancreatography (ERCP) in a 14-year-old male with asplenia-type HS that involved unique imaging findings and technical difficulties. His anatomic anomalies included complex congenital heart disease, midline liver placement, an absent spleen, a left-sided inferior vena cava, and dextroposition of the stomach and pancreas. He suffered from choledocholithiasis with obstructive jaundice, and the stone was successfully extracted with a basket following endoscopic papillary balloon dilation.

CONCLUSION

Although anatomic anomalies in HS increase the degree of technical difficulty when performing ERCP, they can be safely managed by experienced endoscopists, as illustrated by the present case. Identifying these variations with imaging modalities and being aware of them before initiating an invasive intervention are crucial to preventing potential complications.
Emergency pancreaticoduodenectomy for pancreatitis-associated necrotic perforation of the distal stomach and full-length duodenum: A case report
Authors: Tong Kui-Nan , Zhang Wei-Tao , Liu Kun , Xu Rui , Guo Wei
Published: October 2024

BACKGROUND

Non-ulcerative necrosis of the stomach and duodenum is rare because of the abundant blood supply in the gastrointestinal tract. Duodenal necrosis is a rare complication of severe acute pancreatitis. Emergency pancreaticoduodenectomy (EPD) is a rare procedure, with extensive duodenal necrosis being one of its indications.

CASE SUMMARY

We here report the case of a 57-year-old man who survived EPD for pancreatitis, which resulted in the necrosis of the distal stomach, full-length duodenum, and part of the jejunum.

CONCLUSION

Despite significant surgical risks, an EPD could be a life-saving procedure in severe cases of pancreatitis.
Primary hepatic leiomyosarcoma masquerading as liver abscess: A case report
Authors: Wu Fang-Nan , Zhang Min , Zhang Kun , Lv Xin-Liang , Guo Jing-Qiang , Tu Chao-Yong , Zhou Qing-Yun
Published: October 2024

BACKGROUND

Primary hepatic leiomyosarcoma (PHL) is a rare malignant tumor and has non-specific clinical manifestations and imaging characteristics, making preoperative diagnosis challenging. Here, we report a case of PHL presenting primarily with fever, with computed tomography imaging showing a thick-walled hepatic lesion with low-density areas, resembling liver abscess.

CASE SUMMARY

The patient was a 34-year-old woman who presented with right upper abdominal pain and fever over 4 days before admission. Based on the patient’s medical history, laboratory examinations, and imaging examinations, liver abscess was suspected. Mesenchymal tumor was diagnosed by percutaneous liverbiopsy and partial hepatectomy was performed. Postoperative pathology revealed PHL. The patient is currently undergoing intravenous chemotherapy with the AD regimen and shows no signs of recurrence.

CONCLUSION

When there is a thick wall and rich blood supply in the hepatic lesion with a large proportion of uneven low-density areas, PHL should be considered.
Unexpected right-sided sigmoid colon in laparoscopy: A case report and review of literature
Authors: Hu Shi-Fu , Liu Xiang-Yu , Liu Han-Bo , Hao Yuan-Yuan
Published: October 2024

BACKGROUND

The presence of a right-sided sigmoid colon is a rare anatomical variation usually discovered incidentally during surgical interventions. This case report details an unexpected right-sided sigmoid colon identified during a laparoscopic appendectomy and examines the pertinent literature to explore its clinical importance.

CASE SUMMARY

A 71-year-old woman presented with acute appendicitis. A preoperative computed tomography (CT) scan showed peri-appendiceal inflammation but no significant anatomical abnormalities. During laparoscopic surgery, an unexpected finding was encountered: The sigmoid colon was situated on the right side and exhibited an abnormal relationship with the cecum and ascending colon. Postoperative pathological examination confirmed appendicitis with no additional pathological findings. The right-sided sigmoid colon anomaly was verified through intraoperative assessment and later re-evaluation with CT and colonographic imaging. The patient underwent a laparoscopic appendectomy and experienced a smooth postoperative recovery.

CONCLUSION

This case highlights the necessity of being attentive to anatomical variations during laparoscopic surgery, particularly when managing appendicitis. A review of the literature indicated that the occurrence of a right-sided sigmoid colon is infrequent and may be associated with anomalies in midgut rotation during embryonic development. Awareness of this variation can help prevent surgical complications and inform future clinical practice.
Preoperative gastric retention in endoscopic retrograde cholangiopancreatography
Authors: Efthymiou Alkiviadis , Kennedy Patrick T
Published: October 2024

We comment on the article by Jia et al , in the World Journal of Gastrointestinal Surgery . We focus mainly on the factors that impair gastric motility and cause gastric retention in the pre-operative setting of endoscopic retrograde cholangiopancreatography (ERCP). ERCP is a complex endoscopic therapeutic procedure, which demands great skill from the endoscopist but also has recognized complications. Gastric retention impairs the endoscopist’s visibility but also increases the risk of complications, such as aspiration pneumonia. Therefore, identifying the factors that predispose to gastric retention alerts the endoscopists of the possible risks and enables them to take evasive action. The authors in the current study by Jia et al developed and validated a predictive model, which incorporates five different factors, i.e. , gender, primary disease, jaundice, opioid use, and gastrointestinal obstruction, which were found to influence gastric retention. This model was shown to have a high predictive value to accurately identify patients at risk for gastric retention before a therapeutic ERCP.
Unlocking the diagnostic potential of vascular endothelial growth factor and interleukin-17: Advancing early detection strategies for hepatocellular carcinoma
Authors: Subramanian Shanmathi , Rajakumar Hamrish Kumar
Published: October 2024

Tian et al investigated the diagnostic value of serum vascular endothelial growth factor (VEGF) and interleukin-17 (IL-17) in primary hepatocellular carcinoma (PHC). Their retrospective study, published in the World Journal of Gastrointestinal Surgery , revealed that the serum levels of VEGF and IL-17 are significantly elevated in PHC patients compared with healthy controls. These biomarkers are closely associated with pathological features such as tumor metastasis and clinical tumor node metastasis stage. A receiver operating characteristic analysis further confirmed the diagnostic efficacy thereof, suggesting that VEGF and IL-17 could serve as valuable tools for early detection and treatment guidance. This study underscores the potential of integrating these biomarkers into clinical practice to increase diagnostic accuracy and improve patient management in PHC.
Role of macroscopic on-site evaluation of endoscopic ultrasound-guided fine-needle aspiration/biopsy: Results of a multicentric prospective study
Authors: Okasha Hussein H , Hussein Hiwa A , Ragab Khaled M , Abdallah Omar , Rouibaa Fedoua , Mohamed Borahma , Ghalim Fahd , Farouk Mahmoud , Lasheen Mohamed , Elbasiony Mohamed A , Alzamzamy Ahmed E , El Deeb Ahmed , Atalla Hassan , El-Ansary Mahmoud , Mohamed Sahar , Elshair Moaz , Khannoussi Wafaa , Abu-Amer Mohamed Z , Elmekkaoui Amine , Naguib Mohammed S , Ait Errami Adil , El-Meligui Ahmed , El-Habashi Ahmed H , Ameen Mahmoud G , Abdelfatah Dalia , Kaddah Mona , Delsa Hanane
Published: October 2024

BACKGROUND

The concept of macroscopic on-site evaluation (MOSE) was introduced in 2015 when the endoscopist observed better diagnostic yield when the macroscopically visible core on MOSE was superior to 4 mm. Recent studies suggest that MOSE by the endoscopist may be an excellent alternative to rapid on-site evaluation, and some classifications have been published. Few studies have assessed the adequacy of histologic cores in MOSE during endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/FNB).

AIM

To evaluate the performance of MOSE during EUS-FNA/FNB.

METHODS

This multicentric prospective study was conducted in 16 centers in 3 countries (Egypt, Iraq, and Morocco) and included 1108 patients with pancreatic, biliary, or gastrointestinal pathology who were referred for EUS examination. We prospectively analyzed the MOSE in 1008 patients with available histopathological reports according to 2 classifications to determine the adequacy of the histological core samples. Data management and analysis were performed using a Statistical Package for Social Sciences (SPSS) version 27.

RESULTS

A total of 1074 solid lesions were biopsied in 1008 patients with available cytopathological reports. Mean age was 59 years, and 509 patients (50.5%) were male. The mean lesion size was 38 mm. The most frequently utilized needles were FNB-Franseen (74.5%) and 22 G (93.4%), with a median of 2 passes. According to 2 classifications, 618 non-bloody cores (61.3%) and 964 good samples (95.6%) were adequate for histological evaluation. The overall diagnostic yield of cytopathology was 95.5%. The cytological examination confirmed the diagnosis of malignancy in 861 patients (85.4%), while 45 samples (4.5%) were inconclusive. Post-procedural adverse events occurred in 33 patients (3.3%). Statistical analysis showed a difference between needle types (P = 0.035) with a high sensitivity of FNB (97%). The analysis of the relationship between the MOSE-score and the final diagnosis showed a significant difference between the different scores of the MOSE (P < 0.001).

CONCLUSION

MOSE is a simple method that allows endoscopists to increase needle passes to improve sample quality. There is significantly higher FNB sensitivity and cytopathology diagnostic yield with good MOSE cores.
Postprandial gastrin-17 level is a useful dynamic marker for atrophic gastritis
Authors: Tan Huck-Joo , Tan Eunice Zhi-Yi
Published: October 2024

Atrophic gastritis and intestinal metaplasia may progress to gastric malignancy. Non-invasive serum biomarkers have been extensively studied and proven to be useful as a screening tool to stratify risk and identify patients for endoscopy to detect early gastric cancer. These non-invasive biomarkers have been endorsed and recommended by many international consensus guidelines. In this letter, we reviewed the literature and evidence supporting the use of serum biomarkers as a dynamic test to monitor the status of atrophic gastritis.
Port and territorial development dynamics in the Caribbean Basin
Authors: Ranély Verge-Dépré Colette , Joncheray Lorenzo
Published: October 2024

This article examines the relationship between ports and territories in the Caribbean, based on a cross-analysis of port and human development trajectories and states. Several indicators are used to highlight the possible existence of correlations between the growth of port activities in this area and the state of human development over the period 2006-2021. The evolution of traffic and port connectivity to liner shipping (UNCTAD's LSCI index), firstly shows a growing hierarchy in favour of a small number of hubs located along the main shipping routes (Caucedo, Freeport, etc.) and close to the Panama Canal (Colon, Cartagena, etc.). These port dynamics can sometimes, particularly with the increase in transhipment traffic in the main hubs, lead to a disconnection from the socio-spatial configuration of the neighbouring areas (in terms of number of inhabitants and surface area less than an hour away by car). Analysis of the human development of Caribbean port regions over the period studied also reveals the non-systematic nature of the links between changes in the HDI and connectivity to maritime transport. These results make it possible to establish several types of cases, thus contributing to the notion of a territorial port.

Cet article étudie les relations entre ports et territoires dans la Caraïbe, à partir de l’analyse croisée des trajectoires et états portuaires avec ceux du développement humain. Plusieurs indicateurs sont mobilisés afin de mettre en évidence l’existence éventuelle de corrélations entre la croissance des activités portuaires et du développement humain dans cet espace, sur la période 2006-2021. L’évolution des trafics conteneurisés et de la connectivité portuaire au transport maritime de ligne (indice LSCI de la CNUCED), montre tout d’abord une hiérarchisation croissante au profit d’un petit nombre de hubs situés le long des principales routes maritimes (Caucedo, Freeport, etc.) et à proximité du canal de Panama (Colón, Carthagène, etc.). Ces dynamiques portuaires peuvent parfois participer, notamment avec la hausse des trafics de transbordement dans les principaux hubs, d’une déconnexion vis-à-vis de la configuration socio-spatiale des territoires attenants (en nombre d’habitants et superficie à moins d’une heure en voiture). L’analyse du développement humain des régions portuaires caribéennes sur la période étudiée révèle aussi le caractère non systématique des liens entre l’IDH et l’évolution de la connectivité au transport maritime. Ces résultats permettent d’établir plusieurs types de cas, contribuant ainsi à la notion de port territorial.
Hubungan Konformitas Teman Sebaya dengan Agresivitas Verbal Pada Remaja di Wilayah Pesisir Pontianak
Authors: Jayantie Elviana , Lestari Widya , Jati Nugroho
Published: October 2024

Remaja dan permasalahannya saat ini perlu menjadi perhatian dari banyak pihak. Hal ini dapat diketahui melalui banyaknya pemberitaan terkait masalah remaja baik di media cetak dan media elektronik. Cepat marah dan agresif merupakan tingkah laku yang terdapat pada remaja. Salah satu faktor penyebab terjadinya agresi verbal berasal dari teman sebaya sendiri. Penelitian ini bertujuan untuk mengetahui adanya hubungan antara konformitas teman sebaya dengan agresivitas verbal pada remaja di wilayah pesisir Pontianak. Metode penelitian ini menggunakan pendekatan kuantitatif dan pengambilan sampel dengan teknik acak kluster. Subjek pada penelitian ini berjumlah 84 remaja di wilayah pesisir Pontianak. Teknik analisis data menggunakan uji hipotesis dengan nilai signifikansi 0.000 < 0.05, yang berarti terdapat hubungan antara konformitas teman sebaya dengan agresivitas verbal. Selanjutnya nilai koefisien determinasi (R Square) adalah sebesar 0.194 yang diartikan bahwa sumbangan efektif konformitas teman sebaya dengan agresivitas verbal sebesar 19,4%, dan sisanya 80,6% dipengaruhi oleh faktor lain yang tidak diteliti pada penelitian ini
Peran Penegakan Hukum Dalam Penyelesaian Konflik Antara Nelayan Lokal Dan Pihak Pengeboran Lepas Pantai
Authors: Candra Candra , Betlen Andrew , Simanjuntak Mangisi
Published: October 2024

Tujuan penelitian ini untuk mengetahui aturan dalam pengelolaan wilayah pengeboran lepas pantai. Untuk mengetahui peran penegakan hukum dalam penyelesaian konflik antara nelayan lokal dan pihak pengeboran lepas Pantai. Di Indonesia, konflik antara nelayan lokal dan pihak pengebor minyak lepas pantai seringkali terjadi . Konflik ini biasanya terjadi karena adanya ketidakpuasan dari nelayan lokal atas aktivitas pengeboran minyak yang dianggap merusak lingkungan, serta menyebabkan berkurangnya hasil tangkapan ikan. Penelitian ini merupakan penelitian hukum normatif. Dalam penelitian hukum dikenal sebagai penelitian hukum yuridis normatif atau penelitian hukum normatif yang hakekatnya adalah menyelidiki aspek internal hukum positif untuk menyelesaikan persoalan internal.Berdasarkan pembahasan dan temuan penelitian yang dianalisis diperoleh kesimpulan bahwa aturan dalam pengelolaan wilayah pengeboran lepas pantai terdiri dari berbagai peraturan perundang-undangan sampai dengan peraturan menteri yang mengatur mengenai penegakan hukum untuk menyelesaikan konflik antara nelayan lokal dan pihak pengeboran lepas pantai. Dari berbagai tantangan pengelolaan wilayah pengeboran lepas pantai, beberapa aspek utama asas kepastian hukum dalam pengeboran lepas pantai terdiri dari kepastian hukum dalam perizinan dan regulasi, kepastian hukum dalam pengelolaan lingkungan, kepastian hukum dalam penegakan aturan dan sanksi, serta kepastian hukum dalam penyelesaian sengketa.
19. yüzyılda Osmanlı-Rus Diplomasisinde Boğazlar: Stratejik Kazanım ve Güç Mücadelesi
Authors: veske ferhat
Published: October 2024

19. yüzyılda, Osmanlı-Rus diplomatik ilişkileri, özellikle Boğazlar üzerindeki stratejik kazanım ve güç mücadelesi etrafında şekillenmiştir. Rusya, 19. yüzyılın başlarından itibaren Karadeniz'e olan ilgisini artırarak, Boğazlar üzerinde kontrol sağlamak amacıyla çeşitli diplomatik girişimlerde bulunmuştur. Osmanlı Devleti ise uluslararası denge politikalarını kullanarak Boğazlar üzerindeki hâkimiyetini sürdürmek için çaba harcamıştır. Bu süreç, 1841 Londra Antlaşması ile doruk noktasına ulaşmıştır. Antlaşma, İngiltere, Rusya, Fransa, Avusturya, Prusya ve Osmanlı temsilcilerini bir araya getirerek Boğazlar'ın statüsünü düzenlemiştir. Bu anlaşma ile Boğazlar'ın kapalılığı devam ederken, Osmanlı Devleti’nin egemenliği güçlendirilmiş ve Rusya'nın genişleme çabalarına sınırlamalar getirilmiştir. Karadeniz ve boğazlar, büyük güçler arasında önemli bir stratejik bölge olarak öne çıkmıştır. Osmanlı Devleti'nin zayıflamasıyla birlikte bölgede ki stratejik önem daha da artmış ve bu durum, diğer büyük güçlerin de bölge üzerinde etkili olma isteğini tetiklemiştir. Sonuç olarak, 19. yüzyılda Osmanlı-Rus Diplomasisinde Boğazlar bölgesindeki stratejik kazanım ve güç mücadelesi, uluslararası ilişkilerde önemli değişimlere yol açmış, Boğazlar, büyük güçler arasında yaşanan rekabetin odak noktası olmuştur. Bu çalışma ile 19. yüzyılda Osmanlı-Rus diplomasisinde yaşanan olayların gelişimini ve etkileşimleri anlatılmaya çalışılmış, Osmanlı-Rus Savaşları ve antlaşmalarının etkileri ele alınmıştır.
American Foreign Policy and the Maritime Declaration of Paris (1856)
Authors: yeneroğlu elif , budak özgür
Published: October 2024

The Maritime Declaration of Paris which was signed at the end of the Crimean war aimed at solving problems regarding rights of neutrals, privateering and blockades. These problems which were sources of conflicts and even wars for a number of centuries were solved in an innovative manner with regards to the development of the rules of international law. The United States of America, which was the defender of neutral rights almost immediately after its independence did not adhere to the Declaration. This preference stemmed from a number of domestic and foreign policy factors that were closely interconnected. The studies of international law often neglect the historical background of the emergence of these rules. However, it is often impossible to comprehend the logic of those rules without analyzing the power politics between states, that is, the political and economic dynamics within which these rules emerged. What is more neglected is US policy and its contributions to the emergence of these rules. Within this framework this study aims to analyze Maritime Declaration of Paris with a view to American foreign policy priorities. As such, the study aims to contribute to the fields of history of international law and history of American foreign policy
Birinci Haçlı Seferi Sırasında Türklerin Tutumu
Authors: görmez duygu
Published: October 2024

26 Ağustos 1071 tarihinde kazanılan Malazgirt Zaferi ile Anadolu coğrafyası hızla Türkleşme sürecine girmiştir. Bu durum başta Bizans İmparatorluğu ve Hristiyan dünyasına endişe vermiştir. Bu endişeli durum neticesinde toplanan Hristiyan dünyası Haçlı Seferi adı altında İstanbul’a gelerek dindaşlarını koruma görevi üstlenmiştir. İstanbul’da toplanan Haçlı ordusu akabinde hızla Anadolu Selçuklu Devleti topraklarına doğru hareket etmiştir. Haçlılar ile yaşanılan bu ilk karşılaşma sonucu I. Kılıç Arslan önderliğindeki Anadolu Selçuklu orduları kolaylıkla Haçlıları bertaraf ederken aynı başarıyı 1097 yılında gerçekleştirememiştir. Kalabalık Haçlı orduları karşısında tek başına baş edemeyeceğini anlayan I. Kılıç Arslan, çareyi bölgede bulunan Türk emirlerine milli birlik ve beraberlik çağrısı yaparak bulmuştur. I. Kılıç Arslan’ın yapmış olduğu çağrıyla toplanan Türk ordusu, Haçlılara karşı birlikte mücadele etmiştir. Nitekim, Türk ordusunun oluşturduğu milli hareket 1098 yılında çözülme noktasına gelmiş ve I. Haçlı Seferi sırasındaki durumunu etkilemiştir.

Anahtar Kelimeler
Interconnected Stock Markets: Analysing Cointegration and Correlation among Global Stock Indices
Authors:   Nagendra Marisetty, Faculty, REVA Business School (RBS), REVA University, Bangalore, Karnataka, India., Marisetty Nagendra
Published: October 2024

This study examines the long-term and short-term relationships among five major global stock indices—NSE NIFTY (India), S&P 500 (USA), FTSE 100 (UK), Hang Seng (Hong Kong), and Nikkei 225 (Japan)—over the period from 2008 to 2023. Using advanced econometric techniques such as Johansen cointegration tests, Engle-Granger residual cointegration test and the Vector Error Correction Model (VECM), the research explores the degree of interconnectedness and cointegration among these indices. The results indicate strong positive correlations between NSE NIFTY, S&P 500, and Nikkei 225, suggesting a growing synchronization of these markets due to global economic integration. Johansen's test reveals the presence of multiple long-term equilibrium relationships, affirming that despite short-term deviations, these markets tend to move together in response to global macroeconomic factors. The analysis further highlights that the S&P 500 and FTSE 100 indices exhibit significant error correction mechanisms, underscoring their leadership role in global market dynamics. In contrast, NSE NIFTY shows a weaker adjustment toward long-term equilibrium, indicating its reactive nature to changes in other global indices, particularly the S&P 500. The study finds that while Hang Seng and Nikkei 225 are connected globally, their short-term linkages appear weaker, likely influenced by regional factors. Overall, the results emphasize the critical influence of the U.S. and Japanese markets on NSE NIFTY, with both long-term cointegration and short-term market dynamics shaping the Indian stock market’s movements. This research offers key insights for investors seeking to understand global stock market interdependencies and manage portfolio risk.
Meningkatkan kemampuan Self Awareness Anak Usia Dini Melalui Stimulasi Kegiatan Seni Tari di TK Angkasa 8
Authors: Ainurrahmah Syifa , . Choiriyah , Rahayu Wening
Published: October 2024

Penelitian ini bertujuan untuk meningkatkan kemampuan self awareness anak usia dini di TK Angkasa 8 melalui stimulasi menari. Subjek penelitian adalah 7 anak usia 5-6 tahun kelompok B.1. Dengan menggunakan model penelitian tindakan kelas Kemmis dan Mc Taggart, pengumpulan data dilakukan melalui observasi, wawancara dan dokumentasi. Kriteria keberhasilan ditetapkan dengan persentase ≥76% dengan kriteria Berkembang Sesuai Harapan (BSH). Hasil penelitian menunjukkan peningkatan kemampuan kesadaran diri dari pra siklus 14,28% (BB), siklus I 42,85% (MB), hingga siklus II 85,71% (BSB), membuktikan efektifitas stimulasi tari dalam meningkatkan kesadaran diri pada anak. berusia dini.
Kata Kunci: Anak Usia Dini, Kesadaran Diri, Seni Tari