bluuebunny/crossref_metadata_2025 huggingface dataset:
CD38 genetic variation is associated with increased personal distress to an emotional stimulus
Authors: Procyshyn Tanya L. , Leclerc Bédard Laury-Ann , Crespi Bernard J. , Bartz Jennifer A.
Published: January 2024

Genetic variation in CD38—a putative oxytocin pathway gene—has been linked to higher oxytocin levels, empathy, and sensitive parenting, but also to more negative interpersonal outcomes (e.g., alienation from friends and family, poorer romantic relationship quality). To reconcile these seemingly contradictory findings, we drew upon the idea that CD38 variation may heighten social-emotional sensitivity and, consequently, make individuals prone to negative emotions in distressing interpersonal situations. To test this hypothesis, we performed a secondary analysis of a dataset including participants’ (n = 171; 94 females) empathic concern (“sympathetic”) and distress-related (“anxious”) responses to an emotional video. Distress responses were higher for the CD38 rs3796863 AA/AC group vs. the CC group (p = 0.03, η2 = 0.027); however, there was no significant effect of genotype for empathic concern responses to the video or for indices of trait empathy. These findings provide preliminary evidence that, in the face of an interpersonal stressor, CD38 genetic variation may predict more self-focused, aversive emotional reactions. More broadly, this finding highlights the need to adopt a more nuanced perspective in which the influence of oxytocin system variation (assessed by oxytocin-related genetic variation) should be considered in light of the social context.
The Hopf whole-brain model and its linear approximation
Authors: Ponce-Alvarez Adrián , Deco Gustavo
Published: January 2024

Whole-brain models have proven to be useful to understand the emergence of collective activity among neural populations or brain regions. These models combine connectivity matrices, or connectomes, with local node dynamics, noise, and, eventually, transmission delays. Multiple choices for the local dynamics have been proposed. Among them, nonlinear oscillators corresponding to a supercritical Hopf bifurcation have been used to link brain connectivity and collective phase and amplitude dynamics in different brain states. Here, we studied the linear fluctuations of this model to estimate its stationary statistics, i.e., the instantaneous and lagged covariances and the power spectral densities. This linear approximation—that holds in the case of heterogeneous parameters and time-delays—allows analytical estimation of the statistics and it can be used for fast parameter explorations to study changes in brain state, changes in brain activity due to alterations in structural connectivity, and modulations of parameter due to non-equilibrium dynamics.
Proton pump inhibitors and potassium competitive acid blockers decrease pembrolizumab efficacy in patients with metastatic urothelial carcinoma
Authors: Iida Keitaro , Naiki Taku , Etani Toshiki , Nagai Takashi , Sugiyama Yosuke , Isobe Teruki , Aoki Maria , Nozaki Satoshi , Noda Yusuke , Shimizu Nobuhiko , Tomiyama Nami , Gonda Masakazu , Kamiya Hiroyuki , Kubota Hiroki , Nakane Akihiro , Ando Ryosuke , Kawai Noriyasu , Yasui Takahiro
Published: January 2024

We elucidated the efficacy of gut microbiome–altering drugs on pembrolizumab efficacy in patients with metastatic urothelial carcinoma (mUC). Clinical data were analyzed retrospectively from 133 patients with mUC who received second-line pembrolizumab therapy between January 2018 and January 2021, following failed platinum-based chemotherapy. We evaluated the effects of gut microbiome–altering drugs (proton pump inhibitors [PPI]/potassium-competitive acid blockers [P-CAB], H2 blockers, antibiotics, non-steroidal anti-inflammatory drugs [NSAIDs], metformin, antipsychotics, steroids, and opioids), taken by patients within 30 days before/after pembrolizumab treatment, on progression-free survival (PFS) and overall survival (OS). Fifty-one patients received PPI/P-CAB (37/14, respectively); H2 blockers, 7; antibiotics, 35; NSAIDs, 22; antipsychotics, 8; metformin, 3; steroids, 11; and opioids, 29. Kaplan–Meier curves revealed PPI or P-CAB users showed shorter PFS than non-PPI-P-CAB users (p = 0.001, p = 0.005, respectively). Multivariate analysis highlighted PPI/P-CAB use as the only independent prognostic factor for disease progression (hazards ratio: 1.71, 95% confidence interval: 1.14–2.07, p = 0.010) but not death (p = 0.177). Proton pump inhibitors/potassium-competitive acid blockers may decrease the efficacy of pembrolizumab therapy for mUC, possibly via gut microbiome modulation.
Mass spectrometry in IgG4-related disease diagnosis
Authors: Onwuka Daniel C. , Chen Luke Y. C. , Zhan Shing H. , Seidman Michael A. , Cartagena Liliana , Killow Veronika , Abou-tak Hosam , Mattman Andre , Carruthers Mollie N.
Published: January 2024

We compared liquid chromatography tandem mass spectrometry (LC–MS/MS) against Binding Site immunonephelometry (BSIN) with regards to these methods’ abilities to diagnose IgG4-related disease (IgG4-RD). IgG subclasses were gathered from laboratory from December 2011 to December 2020. The IgG4-RD positive and negative patients were diagnosed according to the ACR/EULAR classification criteria by extensive chart review. Both methods’ results were compared in terms of test characteristics. For BSIN, there were 43 IgG4-RD positive cases and 174 disease negative cases, while for LC–MS/MS, there were 102 IgG4-RD positive cases and 562 disease negative cases. The majority of IgG4-RD patients by BSIN and LC–MS/MS had an elevated IgG4 level, 81% and 86%, respectively. For BSIN, the ROC curve, cut-off value of 1.25 g/L, had a sensitivity of 81% and a specificity of 84%. For LC–MS/MS, the ROC curve, cut-off value of 1.25 g/L, had a sensitivity of 86% and a specificity of 84%. The responder index score to IgG4 level r-correlation value for BSIN and LC–MS/MS was 0.5 and 0.6, respectively. In our center, LC–MS/MS and BSIN are equivalent test methods in IgG4-RD diagnosis. IgG4 level does correlate with disease activity by the responder index. LC–MS/MS is a valid and equally reliable alternative to BSIN in the diagnosis of IgG4-related disease.
Larval precompetency and settlement behaviour in 25 Indo-Pacific coral species
Authors: Randall Carly J. , Giuliano Christine , Stephenson Briony , Whitman Taylor N. , Page Cathie A. , Treml Eric A. , Logan Murray , Negri Andrew P.
Published: January 2024

Knowledge of coral larval precompetency periods and maximum competency windows is fundamental to understanding coral population dynamics, informing biogeography and connectivity patterns, and predicting reef recovery following disturbances. Yet for many species, estimates of these early-life history metrics are scarce and vary widely. Furthermore, settlement cues for many taxa are not known despite consequences to habitat selection. Here we performed a comprehensive experimental time-series investigation of larval settlement behaviour, for 25 Indo-Pacific broadcast-spawning species. To investigate the duration of precompetency, improve predictions of the competency windows, and compare settlement responses within and amongst species, we completed replicated and repeated 24-hour assays that exposed larvae to five common settlement cues. Our study revealed that larval competency in some broadcast-spawning species begins as early as two days post fertilization, but that the precompetency period varies within and between species from about two to six days, with consequences for local retention and population connectivity. We also found that larvae of some species are competent to settle beyond 70 days old and display complex temporal settlement behaviour, challenging the assumption that competency gradually wanes over time and adding to the evidence that larval longevity can support genetic connectivity and long-distance dispersal. Using these data, we grouped coral taxa by short, mid and long precompetency periods, and identified their preferred settlement cues. Taken together, these results inform our understanding of larval dynamics across a broad range of coral species and can be applied to investigations of population dynamics, connectivity, and reef recovery.
Female Aedes aegypti mosquitoes use communal cues to manage population density at breeding sites
Authors: Costa-da-Silva Andre Luis , Cabal Silvia , Lopez Kristian , Boloix Jean , Rodriguez Brian Garcia , Marrero Kaylee M. , Bellantuono Anthony J. , DeGennaro Matthew
Published: January 2024

Where a female mosquito lays her eggs creates the conditions for reproductive success. Here we identify a communal behavior among ovipositing female mosquitoes. When choosing equal breeding sites, gravid Aedes aegypti aggregate more often than expected. This aggregation occurs when water contact is restricted and does not require the presence of eggs. Instead, the aggregation is regulated by the number of females present at the breeding site. Using assays with both occupied and empty oviposition sites, we show that the Orco olfactory co-receptor and a carbon dioxide receptor, Gr3, detect the presence of mosquitoes. orco mutants aggregate more often in empty sites, suggesting attractive olfactory cues influence females to associate with one another. Gr3 mutant females do not prefer either site, suggesting that the CO2 receptor is necessary to evaluate mosquito population density at breeding sites. Further, raising CO2 levels is sufficient to cause wild-type mosquitoes to avoid empty oviposition sites. Our results demonstrate that female mosquitoes can regulate their own population density at breeding sites using attractive and repellent communal cues.
Shifting reef restoration focus from coral survivorship to biodiversity using Reef Carpets
Authors: Horoszowski-Fridman Yael B. , Izhaki Ido , Katz Sefano M. , Barkan Ronen , Rinkevich Baruch
Published: January 2024

To enhance the practice of farmed-coral transplantation, we conducted a trial of an approach called “Reef Carpets” (RC), which draws inspiration from the commercial turf-grass sod in land-based lawn gardening. Three 8.4m2 RCs were established on a sandy seabed, containing preselected combinations of branching corals (Acropora cf. variabilis, Pocillopora damicornis, Stylophora pistillata) with nursery recruited dwellers, and were monitored for 17-months. Corals within RCs grew, supported coral recruitment and offered ecological habitats for coral-associated organisms. While the unstable sediment underneath the RCs increased corals’ partial mortalities, corals managed to grow and propagate. The extent of fish and gastropods corallivory varied among the coral species and planulation of Stylophora transplants was significantly higher than same-size natal-colonies. The RCs provided conducive environments for fish/invertebrate communities (183 taxa), and each coral species influenced specifically species-diversity and reef-associated communities. Even dead corals played crucial roles as habitats for reef biota, sustaining >80% of the RCs diversity; hence, they should not be considered automatically as indicators of failure. RCs scaled-up reef restoration and generated, in short periods, new reefs in denuded zones with enhanced biodiversity. Yet, RCs employment on soft-beds could be improved by using more structured artificial frameworks, requiring further research efforts.
Swiss agriculture can become more sustainable and self-sufficient by shifting from forage to grain legume production
Authors: Keller Beat , Oppliger Corina , Chassot Mirjam , Ammann Jeanine , Hund Andreas , Walter Achim
Published: January 2024

Switzerland’s livestock production causes high environmental costs and depends strongly on feed imports. While plant-based protein demand increases, the local grain legume production is negligible ( ~ 9000 hectares). Here, we investigated the potential of sustainable legume protein production based on an expert survey followed by a quantitative analysis based on yield, soil, terrain and climate data.

Pea, soybean and faba bean showed high potential for Swiss agriculture given adaptions in policy, pricing and breeding. The potential grain legume production area was 107,734 hectares on suitable arable land (Scenario I). Switzerland’s self-sufficiency could be increased by cutting imports and maximizing legume production on 181,479 hectares (Scenario II) in expense of grassland and fodder maize. This would replace approximately 41% of animal protein consumption with plant-based protein, preserving 32% of milk and 24% of meat protein. In conclusion, domestic legume production could be substantially increased while improving human and environmental health.
Towards unconstrained catalyst shaping: high accuracy DLP printing of porous γ-Al2O3-based catalysts
Authors: Mastroianni Luca , Russo Vincenzo , Eränen Kari , Di Serio Martino , Murzin Dmitry Yu. , Salmi Tapio
Published: January 2024

The potential of the high resolution DLP printing was exploited to create a new procedure for the design, manufacturing, and application of catalyst structures with a high geometrical complexity.
Local scale air quality impacts in the Los Angeles Basin from increased port activity during 2021 supply chain disruptions
Authors: Skipper T. Nash , Kaiser Jennifer , Odman M. Talat , Hasheminassab Sina , Russell Armistead G.
Published: January 2024

Satellite data, surface observations, and a chemical transport model are used to estimate the impacts of increased port activity during 2021 supply chain disruptions on NO2 and PM2.5 in Los Angeles, California.
Identification and quantification of diffuse groundwater pollution in a mineralised watershed
Authors: Todd Aaron M. L. , Robertson Iain , Byrne Patrick , Walsh Rory P. D. , Williams Tom , Edwards Paul
Published: January 2024

Locating and quantifying sources of metals in a mineralised catchment, using tracer injection and synoptic sampling.
Association between dietary intake of saturated fatty acid subgroups and breast cancer risk
Authors: Jiang Ying , Li Lan-Ting , Hou Si-Han , Chen Le-Ning , Zhang Cai-Xia
Published: January 2024

The impact of dietary saturated fatty acids (SFAs) on breast cancer risk may vary depending on their carbon chain lengths, attributable to the discrepancy in their dietary sources and biological activities.
Facile and sustainable recovery of spent LiFePO4 battery cathode materials in a Ca(ClO)2 system
Authors: Liu Gongqi , Liu Zejian , Gu Jing , Wang Shujia , Wu Yufeng , Yuan Haoran , Chen Yong
Published: January 2024

This work introduces a sustainable and economical process for the simultaneous recovery of Li and Fe/P from spent LiFePO4 batteries in the Ca(ClO)2 system.
Recent advances in removal of pharmaceutical pollutants in wastewater using metal oxides and carbonaceous materials as photocatalysts: a review
Authors: Srivastava Suneel Kumar
Published: January 2024

The pharmaceuticals industry has played an important role in developing medicines for improving health and quality of life in treating humans and animals around the world.
Injectable extracellular matrix-mimetic hydrogel based on electrospun Janus fibers
Authors: Zhang Jinzhong , Zha Xiaolong , Liu Gengxin , Zhao Huipeng , Liu Xiaoyun , Zha Liusheng
Published: January 2024

To date, the reported injectable hydrogels have failed to mimic the fibrous architecture of the extracellular matrix (ECM), limiting their biological effects on cell growth and phenotype.
In-operando FTIR study of ligand-linked Pt nanoparticle networks employed as catalysts in hydrogen gas micro sensors
Authors: Loof Daniel , Thüringer Oliver , Zielasek Volkmar , Pranti Anmona Shabnam , Lang Walter , Bäumer Marcus
Published: January 2024

Pt nanoparticles linked by aromatic diamines make superior combustion catalysts in H2 microsensors. Their long-term performance is probably based on diamine decomposition and formation of a sponge-like Pt nanostructure during catalyst activation.
Rate retardation trends in RAFT – an emerging monomer classification tool?
Authors: Nwoko Tochukwu , Nguyen Khoi , Saha Nirob K. , Barner-Kowollik Christopher , Konkolewicz Dominik
Published: January 2024

The RAFT rate retardation effect is used to classify monomers according to their reactivity. The stability of the radical correlates inversely with the extent of retardation allowing a framework for classifying monomer reactivity to be established.
(o-CF3PhO)3P as a simple coupling reagent for direct amidation via activation of amines
Authors: Zhang Lin , Ma Nana , Wang Mei , Gou Wenchang , Tian Jie , Xu Qian , Zhao Chong , Li Chun
Published: January 2024

A new coupling reagent was applied in a simple and unprecedented manner for direct amidation. This approach enabled amide bond formation via activation of amines, which was verified by control experiments and DFT calculations.
Recent advances in nickel-catalyzed propargylic substitution
Authors: Tong Feifei , Hu Dandan , Zhang Chun , Zhang Jun-Qi , Ren Hongjun
Published: January 2024

This work summarizes recent progress in nickel-catalyzed propargylic substitution reactions, categorizing them based on the diverse types of nucleophiles involved, with a specific focus on exploring asymmetric transformations.
Controlled Sr(ii) ion release from in situ crosslinking electroactive hydrogels with potential for the treatment of infections
Authors: Fırlak Demirkan Melike , Öztürk Dilek , Çifçibaşı Zeynep Sude , Ertan Fatma , Hardy John George , Nurşeval Oyunlu Aslı , Darıcı Hakan
Published: January 2024

The first example of Sr2+ ion release from in situ crosslinking electroactive hydrogels in response to the application of electricity.
Fe-doped nanodiamond-based photo-Fenton catalyst for dual-modal fluorescence imaging and improved chemotherapeutic efficacy against tumor hypoxia
Authors: Selvam Rajakar , Pearl Wrenit Gem , Perevedentseva Elena , Karmenyan Artashes , Cheng Chia-Liang
Published: January 2024

FeND loaded with DOX representing a promising theranostic agent for chemo/chemodynamic therapy.
Discovery of new tetrazines for bioorthogonal reactions with strained alkenes via computational chemistry
Authors: Májek Michal , Trtúšek Matej
Published: January 2024

Secondary orbital interaction in action: DFT calculations in combination with the distortion–interaction model help to uncover underlying factors responsible for the increased reactivity of sulfone- and sulfoxide-substituted tetrazines in iEDDA.
Combustion properties and pollutant analysis of coal-blended bio-heavy oil fuel
Authors: Bai Yuan , Sun Yuqing , Pan Haojun , Wang Sheng , Dong Yuehong , Chen Bin , Qiu Jian , Jing Wenheng
Published: January 2024

Coal blending with bio-heavy oil enhances the combustion calorific value of the fuel, improves combustion characteristics, and decreases pollutant emissions.
Fluorine-free nanoparticle coatings on cotton fabric: comparing the UV-protective and hydrophobic capabilities of silica vs. silica-ZnO nanostructures
Authors: Liu Irene ChaoYun , Hu Xin , Fei Bin , Lee Chenghao , Fan Suju , Xin John H. , Noor Nuruzzaman
Published: January 2024

Robust, hydrophobic woven cotton fabrics were obtained through the sol–gel dip coating of two different nanoparticle (NP) architectures; silica and silica-ZnO.
The effect of electrolyte with binary solvents on improving the performance of rechargeable lithium–oxygen batteries
Authors: Liu Tie , Li Wenjing , Zhang Guangwei , Yu Aishui
Published: January 2024

A bi-solvent electrolyte (G3/DMSO) was explored as a critical component to improve LOB performance from the perspective of electrolyte selection were rationally discussed. Cell capacity, coulombic efficiency and cycle life were all improved.
One-step synthesis of a highly crystalline covalent organic framework with olefin and imine dual linkages for tuning the catalytic activity
Authors: Sun Qing , Jiang Shaodong , Niu Hongyun , Li Ying , Wu Xiaodong , Shi Yali , Cai Yaqi
Published: January 2024

Introducing a novel one-step method for synthesizing a highly crystalline COF with olefin and imine dual linkages, resulting in improved photocatalytic degradation of pollutants and unique 1O2 generation capabilities compared to imine-linked COFs.
Effect of the rigidity of an organic interlayer on the nonradiative recombination and exciton dissociation in hybrid Dion–Jacobson 2D lead iodide perovskites
Authors: Sun Kexuan , Meng Yuanyuan , Cao Ruikun , Ren Yumin , Mao Yuhong , Tian Ruijia , Wang Yaohua , Lü Xujie , Liu Chang , Ge Ziyi
Published: January 2024

3AMP-based 2D perovskites produce higher rigidity octahedral structures through more symmetric hydrogen bonding, ultimately resulting in weaker electron–phonon coupling and lower defect density.
A preliminary investigation of microbial communities on the Athabasca Glacier within deposited organic matter
Authors: Esser Milena , Ankley Phillip , Aubry-Wake Caroline , Xie Yuwei , Baulch Helen , Hoggarth Cameron , Hecker Markus , Hollert Henner , Giesy John P. , Pomeroy John W. , Brinkmann Markus
Published: January 2024

Glacier ecosystems are shrinking at an accelerating rate due to changes in climate, and increased darkening from allochthonous and autochthonous carbon is leading to changes in light absorption, associated heat, and microbial communities.
Invertebrate Diversity in Gastrointestinal Fejervarya cancrivora rice Fields in Ciomas, Bogor Regency
Authors: Pratomo Hurip , Susilo Adhi , Rosadi Bayu
Published: January 2024

Frogs that live in rice paddy habitats in Indonesia include Fejervarya limnocharis and Fejervarya cancrivora. The species of invertebrate eaten by Fejervarya cancrivora is still little known, so research needs to be done to analyze the species of invertebrate eaten by the frog. Samples of Fejervarya cancrivora frogs were randomly captured at two consecutive nights in the rice fields area of Ciomas sub-district, Bogor Regency and then 20% of the total catch was taken to be anesthetized, the rest was released back to the rice fields. The collection of invertebrates is taken from the gastrointestinal part of the toad. Identification of invertebrate species is carried out on some recognizable body remains of invertebrates. Based on the calculation of the Shannon-Winner Diversity Index, the species of invertebrate found in the female gastro intestinal Fejervarya cancrivora throughout the night has an index value of H* = 0.948, while the invertebrates in the gastrointestinal Fejervarya cancrivora male have an index value of H* = 0.845. Species of invertebrates found in gastrointestinal Fejervarya cancrivora include: Conocephalus longipenis, Panstenon nr. Collaris boucek, Pachydiplossis oryzae, Hydrella philippina, Haplothrips aculeatus, Microvelia douglasi (microvelia), Snellenius (Microplitis) manilae, Cnaphalocrosis medinalis, Oncomelania sp., Chilo supressalis. Euborellia stali (Dohrn), Gonatocerus sp., Dicladispa armigera, Oxyopes javanus, leftover leg crustaceans, Brachymeria lasus, and Nilaparvata lugens.
Green Entrepreneurship Incubation Model for Students at Trilogy University Business Incubator: A Literature Review
Authors: Maulidian  , Puspitawati Mutiara Dewi , Novita  , Ramayanti Rizka , Dahlia Lely , Purnengsih Iis
Published: January 2024

Green entrepreneurship, which emphasizes sustainable economic methods, has grown rapidly in recent decades. Green startups are supported by several incubation programs worldwide. Their frameworks, resources, and mentorship tactics have changed to meet new requirements. This study explores these paradigms in Trilogi University’s academic and cultural milieu. Second, this research analyzes global green entrepreneurship incubation models’ frameworks, resources, and mentorship methods. Second, to evaluate these models’ suitability for Trilogi University. A systematic literature study was conducted using academic databases. The evolution of green entrepreneurship incubation approaches was highlighted in 1990–2023 articles. A rigorous two-stage review and theme analysis were used to organize retrieved data into trends and difficulties, notably at universities. The study examines incubation frameworks, resource diversification, and mentorship strategy development. Various worldwide models are investigated, focusing on Trilogi University. The study highlights the benefits of integrating these approaches in academic contexts, such as multidisciplinary collaboration and access to huge resources. This study connects global incubation models to university environments, preparing future researchers. Global best practises can help academic institutions, like Trilogi University, optimise their incubation methods. The report recommends addressing scalability and funding dynamics to help green businesses grow in academia.
The Impact of Quizlet on the Transferability of Vocabulary in English as a Foreign Language (EFL) Learners: Student Perspectives
Authors: Ningsih Rahma Pitria , Nasrullah Nasrullah , Rosalina Elsa
Published: January 2024

Proficiency in vocabulary is a crucial skill for engineering students as it facilitates comprehension of engineering manuals and other literature predominantly composed in English. The efficacy of the classical method in enhancing vocabulary proficiency is regarded as leading to the development of an android-based Quizlet application as a potential solution to address this issue. This study aims to examine students’ perceptions regarding the effectiveness of Quizlet as a self-study tool for enhancing their proficiency in Engineering English vocabulary. The research utilized a quantitative descriptive methodology. The study employed questionnaires administered through Google Forms as the primary instruments. These questionnaires were distributed to twenty-five students enrolled in Mechanical Engineering program at Banjarmasin State Polytechnic. The present study employed a descriptive approach to analyze the data, utilizing the Likert scale as a measurement tool. According to the study’s findings, it has been established that most students exhibit a favorable reaction toward using the Quizlet application. Approximately 48.7% of the respondents’ answers agreed with each posed question, while a mere 1.4% expressed a strong disagreement. The findings indicate that using the Quizlet application as a learning tool on the Android platform can potentially enhance vocabulary retention.
Feasibility and Safety of Cone-Beam Computed Tomography Advanced Navigation to Optimize Intra-arterial Chemotherapy Infusion of Skull Base Tumors
Authors: Cornelis Francois H. , Lis Eric , Tabar Viviane , Lin Andrew
Published: January 2024

Purpose To assess the feasibility and safety of cone-beam computed tomography (CBCT) advanced navigation for optimizing intra-arterial chemotherapy infusion (IACI) in patients with skull base tumors.

Materials and Methods Retrospective review on 10 consecutive IACI procedures performed in five patients (four women, 1 man) over a 1-year period. The median age of the patients was 71 years (interquartile range: 34–74). During the procedures, a CBCT-based navigation software was employed to evaluate tumor perfusion and guide the infusion methods. Catheterization of the primary tumor feeding vessel was performed in seven cases when it originated from the external carotid artery, whereas a temporary balloon-assisted occlusion technique was utilized in the remaining three cases where the tumor was primarily fed by the internal carotid artery. Carboplatin, topotecan, and melphalan were injected over a 10-minute period. Fluoroscopy time, reference dose, and Kerma area product, which estimates effective dose, were analyzed.

Results The technical success rate was 100%, with a median procedure length of 82 minutes (79–90). The median fluoroscopy time was 11.3 minutes (9.4–16.9), reference dose was 93.5 mGy (62–256.5), and Kerma area product was 11.6 Gy.cm2 (9.5–25.4). The median effective dose was 3.8 mSv (1.5–5.1). The median follow-up duration was 233.5 days (186.3–432). One severe adverse event was reported, involving a right brachial hematoma and brachiocephalic artery dissection related to catheterization through a type III aortic arch. Three patients exhibited disease progression, but two patients showed stable disease.

Conclusion IACI for skull base tumors guided by CBCT navigation is both feasible and safe.
Prevalence of Oral Normal Variances in Cigarette Factory Workers in Lamongan, Indonesia
Authors: Femilian Afryla , Radithia Desiana , Surboyo Meircurius Dwi Condro , Pertiwi Aulya Setyo , Marsetyo Riyan Iman
Published: January 2024

Objective This study aims to observe the distribution of oral normal variances in cigarette factory workers. An essential aspect of diagnosing oral mucosal lesions is differentiating between abnormalities and normal oral variances. Workers from cigarette factories tend to neglect their oral health because of their occupational environment. Lack of awareness in identifying oral mucosal conditions led to poor oral health of cigarette factory worker.

Materials and Methods A cross-sectional study; the sample population included 101 cigarette factory workers who participated in oral screening. The predictor variables in this study included all oral normal variances.

Results The prevalence of oral normal variances in this study was as the following: torus palatinus (62.38%), crenated tongue (51.49%), coated tongue (46.53%), linea alba buccalis (37.62%), fissured tongue (25.74%), prominent Stensen's duct (17.82%), lingual varix (9.90%), ankyloglossia (4.95%), torus mandibularis (3.96%), Fordyce's spots (1.98%), frictional keratosis (1.98%), and macroglossia (0.99%).

Conclusion Top three common normal oral variances among cigarette factory workers are torus palatinus followed by crenated tongue and coated tongue.
The Relationship between Patient Load and Nursing Staffing Strength in Various Shifts of the Day in Emergency Department of a Major Tertiary Care Hospital in India
Authors: Mehra Manisha , Robin Metilda , Agrawal Deepak
Published: January 2024

Introduction A hospital has to function 24 hours a day, which makes shift duties almost inescapable for the nurses. However, shift wise staffing of nursing in emergency departments (EDs) of most hospitals continues to parallel that of other clinical departments.

Objective The aim of this study was to see the adequacy of staffing in reference to patient load in the different shifts of the day in the ED of a major tertiary care hospital in India.

Methods This is a prospective cross-sectional study. The number of patients entering the ED in each shift as well as the number of nurses assigned in each shift were taken from the rotation over a period of 1 week. A single point questionnaire was also administered to all five nurses in each shift over the study period to assess staff perception of patient load in the shift. Ethics approval was taken from institutional ethics committee.

Results For calculating the differential patient load in different shifts. We have calculated the average number of registered patients entering the emergency in over 1 week was 24 in the morning shift, 24 in the evening shift, and 81 in the night shift. The average nursing strength was 11 in morning shift, 11 in the evening shift, and 10 in the night shift. The average response from 15 nurses after interviewing them was 1 (overstaffed) in the morning, 2 (properly staffed) in the evening shift (properly staffed), and 4 in the night shift.

Conclusion The ratio of registered patients entering the emergency and the number of nurses deployed in each shift does not match, which gives an important view to revise roster in such a way that will not compromise the patient care.
Automated Midline Shift Detection and Quantification in Traumatic Brain Injury: A Comprehensive Review
Authors: Agrawal Deepak , Joshi Sharwari , Poonamallee Latha
Published: January 2024

Traumatic brain injury (TBI) often results in midline shift (MLS) that is a critical indicator of the severity and prognosis of head injuries. Automated analysis of MLS from head computed tomography (CT) scans using artificial intelligence (AI) techniques has gained much attention in the past decade and has shown promise in improving diagnostic efficiency and accuracy. This review aims to summarize the current state of research on AI-based approaches for MLS analysis in TBI cases, identify the methodologies employed, evaluate the performance of the algorithms, and draw conclusions regarding their potential clinical applicability. A comprehensive literature search was conducted, identifying 15 distinctive publications. The identified articles were analyzed for their focus on MLS detection and quantification using AI techniques, including their choice of AI algorithms, dataset characteristics, and methodology. The reviewed articles covered various aspects related to MLS detection and quantification, employing deep neural networks trained on two-dimensional or three-dimensional CT imaging datasets. The dataset sizes ranged from 11 patients' CT scans to 25,000 CT images. The performance of the AI algorithms exhibited variations in accuracy, sensitivity, and specificity, with sensitivity ranging from 70 to 100%, and specificity ranging from 73 to 97.4%. AI-based approaches utilizing deep neural networks have demonstrated potential in the automated detection and quantification of MLS in TBI cases. However, different researchers have used different techniques; hence, critical comparison is difficult. Further research and standardization of evaluation protocols are needed to establish the reliability and generalizability of these AI algorithms for MLS detection and quantification in clinical practice. The findings highlight the importance of AI techniques in improving MLS diagnosis and guiding clinical decision-making in TBI management.
Cognitive Profiles of Mild Traumatic Brain Injury and mild Vascular Cognitive Impairment: A Comparative Study
Authors: Menon Ramshekhar N. , Ramachandran Sushama S. , Karunakaran Parvathy P.
Published: January 2024

Objective The cognitive profile of any neurological disorder is very important throughout the duration of a person's treatment. It has a role in diagnosis, prognosis, and even after remission of active symptoms. It is a common trend among clinicians to monitor and compare the cognitive profiles of different disease conditions to locate the area of maximum dysfunction, with respect to a particular diagnosis. This study correlates the cognitive profiles of mild traumatic brain injury (mTBI) and mild vascular cognitive impairment (mVCI).

Materials and Methods The study population comprised 30 mTBI and 30 mVCI patients medically diagnosed by a neurologist. The patients were been selected from the neuromedical outpatient department (OPD) and neurosurgery OPD of the Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum. Simple random sampling had been used to select the sample. The patients diagnosed with the stated disease conditions were referred for neuropsychological assessment. Testable and cooperative patients were recruited for the study. To stabilize the data and for a transparent comparison, 30 healthy controls with no medically diagnosed illnesses were also added to the study. The results were analyzed using R.

Results and Conclusion The study concluded that cognitive profiles of mTBI and mVCI patients were significantly different from the cognitive profiles of healthy controls, but there was no statistically significant difference between the cognitive profiles of mVCI and mTBI patients except in confrontation naming and recognition memory.
Digital diplomacy and domestic audience: how official discourse shapes nationalist sentiments in China
Authors: Zhang Xiaowen , Tang Yuxin
Published: January 2024

This article aims to reveal the domestic implications of China’s digital diplomacy by centring the interaction between official diplomatic discourses and Chinese nationalist sentiments. Examining diplomatic discourse presented by Chinese foreign affairs spokespersons and the related nationalist comments of the Chinese domestic audience, this study illustrates the dynamic interplay between official diplomatic discourses, the salience of other, and nationalist sentiments. The findings suggest that China’s digital diplomatic discourse can influence the dynamic of domestic nationalist sentiments. A positive diplomatic tone contributes to more positive nationalist sentiments through an enhanced sense of national identification. Conversely, a negative tone of diplomatic discourse tends to generate more negative nationalist sentiments through intensified social comparison and derogation, particularly in the presence of salient foreign others. The study puts forward the theoretical commensurability between digital diplomacy, social identity theories, and nationalism construction. It also offers practical insights into China’s multifaceted nationalist communication and digital diplomacy strategies.
Rural settlement of urban dwellers in China: community integration and spatial restructuring
Authors: Zheng Nana , Wang Shengcong , Wang Hengyu , Ye Shuqi
Published: January 2024

With rapid urbanization in China, an increasing number of urban dwellers are migrating to rural areas, becoming “new villagers”. This phenomenon provides both opportunities and challenges for rural revitalization. This study aims to examine the community integration dilemmas of these new villagers from the perspective of social space production theory. Through oral history investigations, in-depth interviews and participant observations, this qualitative study explores the integration predicaments of new villagers across four dimensions—living space, production space, cultural space, and social space. The findings indicate that the integration dilemmas arise from disparities between new villagers and native villagers in status, cultural identity, values, and customs. New villagers face risks of exclusion in obtaining living space, cultural conflicts in production activities, value clashes with traditional rural culture, and social closure from existing rural networks. To better integrate new villagers into local communities, fostering cultural communication, shaping common values, and restructuring rural space are essential, providing insights for rural talent retention policies. This research offers implications for rural talent revitalization mechanisms in the context of urban–rural migration in China.
Analysis of the agricultural economic value of a weather forecasting service based on a survey of peasant households in Chinese provinces
Authors: Shen Danna , Zhao Xiaofeng , Chai Leyi , Guo Zhuanzhuan , Leng Chunxiang
Published: January 2024

The enhancement of weather forecasting capabilities plays a pivotal role in agricultural production, storage, and transportation. This paper conducts a comprehensive survey among agricultural producers across 31 provinces and over 1000 counties in China using household questionnaires. The collected data is analyzed utilizing a multiple linear regression model that incorporates clustering and robust standard errors to ensure accurate results. The findings reveal a positive correlation between the frequency at which agricultural production entities pay attention to meteorological forecast information and the subsequent incremental increase in their income. Moreover, it is observed that both the number of access channels to meteorological information and their frequency significantly impact the rise in agricultural income attributed to such forecasts. Specifically, each additional type of access channel leads to an average income increase of 11.11 yuan. Furthermore, through regression analysis, this study demonstrates statistically significant effects of meteorological forecasts on cost savings as well as income growth within the realm of agricultural production.
Synthesis technique and electron beam damage study of nanometer-thin single-crystalline thymine
Authors: Daoud Hazem , Pulleri Vadhyar Sreelaja , Nikbin Ehsan , Lu Cheng , Miller R. J. Dwayne
Published: January 2024

Samples suitable for electron diffraction studies must satisfy certain characteristics such as having a thickness in the range of 10–100 nm. We report, to our knowledge, the first successful synthesis technique of nanometer-thin sheets of single-crystalline thymine suitable for electron diffraction and spectroscopy studies. This development provides a well-defined system to explore issues related to UV photochemistry of DNA and high intrinsic stability essential to maintaining integrity of genetic information. The crystals are grown using the evaporation technique, and the nanometer-thin sheets are obtained via microtoming. The sample is characterized via x-ray diffraction and is subsequently studied using electron diffraction via a transmission electron microscope. Thymine is found to be more radiation resistant than similar molecular moieties (e.g., carbamazepine) by a factor of 5. This raises interesting questions about the role of the fast relaxation processes of electron scattering-induced excited states, extending the concept of radiation hardening beyond photoexcited states. The high stability of thymine in particular opens the door for further studies of these ultrafast relaxation processes giving rise to the high stability of DNA to UV radiation.
Solute-enhanced twin boundary migration in CuAg alloy
Authors: Chen Dengke , Zhang Yin , Xu Shuozhi
Published: January 2024

Understanding the mechanical behavior of nanotwinned materials in alloys is essential, particularly in relation to solute-influenced twin boundary (TB) migration. This research employs atomistic simulations and theoretical analysis to explore the influence of solute atoms on TB migration in CuAg alloys. Contrary to conventional beliefs, simulations reveal that solute Ag atoms enhance TB migration, challenging established perceptions. Nudged elastic band calculations confirm that Ag solutes substantially reduce energy barriers, shedding light on the mechanism driving solute-enhanced TB migration. This work opens novel avenues for investigating point defect impacts on TB mobility, offering insights into alloy element roles in grain boundary migration and polycrystalline material properties.
Dubrovin–Frobenius manifold structures on the orbit space of the symmetric group
Authors: Wu Yemo , Zuo Dafeng
Published: January 2024

By choosing different Sl-invariant metrics, we show the existence of (l − 1) different Dubrovin–Frobenius manifold structures on the orbit space of the symmetric group and also construct Landau–Ginzburg superpotentials for these Dubrovin–Frobenius manifold structures.
Metal-free carbazole–thiophene photosensitizers designed for a dye-sensitized H2-evolving photocatalyst in Z-scheme water splitting
Authors: Nakada Akinobu , Yokota Takayuki , Ogura Morihiko , Chang Ninghui , Tomita Osamu , Saeki Akinori , Ogasawara Masamichi , Abe Ryu
Published: January 2024

Dye-sensitized photocatalysts with molecular dyes and widegap semiconductors have attracted attention because of their design flexibility, for example, tunable light absorption for visible-light water splitting. Although organic dyes are promising candidates as metal-free photosensitizers in dye-sensitized photocatalysts, their efficiency in H2 production has far been unsatisfactory compared to that of metal-complex photosensitizers, such as Ru(II) tris-diimine-type complexes. Here, we demonstrate the substantial improvement of carbazole–thiophene-based dyes used for dye-sensitized photocatalysts through systematic molecular design of the number of thiophene rings, substituents in the thiophene moiety, and the anchoring group. The optimized carbazole–thiophene dye-sensitized layered niobate exhibited a quantum efficiency of 0.3% at 460 nm for H2 evolution using a redox-reversible I− electron donor, which is six-times higher than that of the best coumarin-based metal-free dye reported to date. The dye-sensitized photocatalyst also facilitated overall water splitting when combined with a WO3-based O2-evolving photocatalyst and an I3−/I− redox shuttle mediator. The present metal-free dye provided a high dye-based turnover frequency for water splitting, comparable to that of the state-of-the-art Ru(II) tris-diimine-type photosensitizer, by simple adsorption onto a layered niobate. Thus, this study highlights the potential of metal-free organic dyes with appropriate molecular designs for the development of efficient water splitting.
Optical and antibacterial activity analysis of pure, Fe-doped, and glucose-capped transparent semiconducting nanoparticles of cadmium and zinc oxides
Authors: Parajuli D. , Murali N. , Shanmukhi P. S. V. , Samatha K.
Published: January 2024

CdO (ZnO) nanoparticles (NPs) are known for their high surface area and quantum confinement. In this paper, there is a discussion on the synthesis of pure, Fe-doped, and glucose-capped CdO (ZnO) NPs by the precipitation method. Their structural and optical properties were studied with the help of XRD, SEM, FTIR, and UV–Vis spectrometry. A single phase with hexagonal (cubic) structures was obtained from their XRD patterns. The pure, Fe-doped, and glucose-capped CdO (ZnO) had crystallite sizes of 15.89, 15.33, and 11.19 nm (1.66, 1.01, and 1.78 nm) obtained from XRD. Their FTIR data agreed well with their XRD data. The particles were spherical. The energy bandgap of CdO (ZnO) was 3.78, 3.65, and 3.63 eV (3.82, 3.80, and 3.63 eV) for pure, Fe-doped, and capped samples, respectively, obtained with the help of photoluminescence. The inhibition zones are found to be 11, 7, and 13 (12, 10, and 7), respectively.
Field-sensitivity and reversibility of the inverse magnetocaloric effect at martensitic transformations
Authors: Taake Chris , Samanta Tapas , Caron Luana
Published: January 2024

The magnetic field-sensitivity of martensitic phase transitions (MPTs) responsible for magnetocaloric effects has been examined in B-substituted Ni50Mn34.8In15.2−xBx Heusler alloys (x = 1, 2, 3, and 4). Increasing boron substitution acts as a positive chemical pressure similar to the effect of hydrostatic pressure (p) and shifts the martensitic phase transition temperature (TM) toward higher temperature. The observed structural compatibility of the MPT results in a lower thermal hysteresis (ΔThyst<5 K at low field). ΔThyst remains almost unchanged; however, the field sensitivity of TM decreases significantly with increasing B content or application of p. As a result, the reversibility of the isothermal entropy change (|ΔSrev|) reduces for higher B concentration or under hydrostatic pressure p. The experimental observation reveals that the lower field-sensitivity of the MPT with increasing B or p is associated with the simultaneous increase in the magnetocrystalline anisotropy energy (MAE) and decrease in the Zeeman energy (ZE). The relatively larger ZE and smaller MAE for x = 1 result in the improved reversibility of the entropy change (|ΔSrev| = 21.48 J/kg K for Δμ0H = 5 T), which is comparable to or even larger than the values reported for similar Heusler alloys.
Surface wave interaction with floating elastic plates in channels
Authors: Ren K. , Wu G. X. , Yang Y. F.
Published: January 2024

The interaction between surface waves and a finite rectangular floating plate in a channel is considered analytically, while the location of the plate is not restricted. The mathematical model is based on the linear velocity potential flow theory for the fluid and the Kirchhoff–Love plate theory for the plate. The problem is converted into an integral equation through using the Green function. The second-order singularity associated with a body with no thickness is treated with the Dirac delta function. The developed scheme is used for case studies of various edge constraints. Extensive results are provided for the hydrodynamic forces acting on the plate and the wave reflection and transmission coefficients. The effects of wave frequency, channel width, plate length, and edge conditions are analyzed, and their physical implications are highlighted. Significant findings comprise the highly oscillatory nature of force curves, influenced by the natural frequencies of the channels and the length of the plate, and substantial effects of edge conditions and the plate position on the results.