bluuebunny/crossref_metadata_2025 huggingface dataset:
Are Trends in Economic Modeling of Pediatric Diabetes Mellitus up to Date with the Clinical Practice Guidelines and the Latest Scientific Findings?
Authors: Cardona-Hernandez Roque , de la Cuadra-Grande Alberto , Monje Julen , Echave María , Oyaguez Itziar , Álvarez María , Leiva-Gea Isabel
Published: February 2025

Background: Modeling techniques in the field of pediatrics present unique challenges beyond traditional model limitations, and sometimes difficulties in faithfully simulating the condition's evolution over time.
Objective: This study aimed to identify whether economic modeling approaches in diabetes in pediatric patients align with the recommendations of clinical practice guidelines and the latest scientific evidence.
Methods: A literature review was performed in March 2023 to identify modeling-based economic evaluations in diabetes in pediatric patients. Data were extracted and synthesized from eligible studies. Clinical practice guidelines for diabetes were gathered to compare their alignment with modeling strategies. Two endocrinology specialists provided insights on the latest findings in diabetes that are not yet included in the guidelines. A multidisciplinary group of experts agreed on the relevant themes to conduct the comparative analysis: parameter informing on glycemic control, diabetic ketoacidosis/hypoglycemia, C-peptide as prognostic biomarker, metabolic memory, age at diagnosis, socioeconomic status, pediatric-specific sources of risk equations, and pediatric-specific sources of utilities/disutilities.
Results: Nineteen modeling-based studies (7 de novo, 12 predesigned models) and 34 guidelines were selected. Hemoglobin A1c was the main parameter to model the glycemic control; however, guidelines recommend the usage of complementary measures (eg, time in range) which are not included in economic models. Eight models included diabetic ketoacidosis (42.1%), 16 included hypoglycemia (84.2%), 2 included C-peptide (1 of those as prognostic factor) (10.5%) and 1 included legacy effect (5.3%). Neither guidelines nor models included recent findings, such as age at diagnosis or socioeconomic status, as prognostic factors. The lack of pediatric-specific sources for risk equations and utility/disutility values were additional limitations.
Discussion: Economic models designed for assessing interventions in diabetes in pediatric patients should be based on pediatric-specific data and include novel adjuvant glucose-monitoring metrics and latest evidence on prognostic factors (C-peptide, legacy effect, age at diagnosis, socioeconomic status) to provide a more faithful reflection of the disease.
Conclusions: Economic models represent useful tools to inform decision making. However, further research assessing the gaps is needed to enhance evidence-based health economic modeling that best represents reality.
Risk factors for late pneumothorax in patients with minor rib fractures after blunt chest trauma
Authors: Esme Hıdır
Published: February 2025

Introduction: Traumatic pneumothorax is a preventable cause of death in trauma patients. Treatment of small traumatic pneumothorax without respiratory distress is controversial. In this study, we tried to determine the risk factors for the development of late traumatic pneumothorax and the safety of treatment with observation in appropriate patients.
Material and Methods: Between August 2020 and December 2023, 167 patients admitted to the emergency department for blunt chest trauma with less than 4 rib fractures were retrospectively analyzed. Age, gender, mechanism of trauma, number of rib fractures, rib fracture location, concomitant traumas and pulmonary complications were recorded.
Results: The study included 167 patients. There were 107 males (%) and 60 females (%). The age of the patients ranged from 17 to 89 years (mean, 52.6 years). Early pneumothorax was seen in 10 patients (0.59%) and late pneumothorax in 9 patients (0.53%). In statistical analysis, there was a significant correlation between late pneumothorax and the number of rib fractures (p=0.001) and subcutaneous emphysema (p=0.023). There was no significant association between late pneumothorax and other parameters.
Conclusion: Increased number of rib fractures and pulmonary complications are harbingers of traumatic pneumothorax. Observation is an adequate treatment modality in late pneumothoraxes without respiratory distress and radiologic progression.
Neuropathic Pain in Lumbar Disc Herniation: A Comparative Study of Surgical Outcomes
Authors: Şanlı Zeynep Selcan , Yılmaz Ahmet
Published: February 2025

Background: This study aimed to assess the prevalence of neuropathic pain in patients diagnosed with lumbar disc herniation and to examine the correlation between neuropathic pain and surgical intervention.
Material and methods: We performed a retrospective cohort study involving 217 patients diagnosed with lumbar disc herniation who reported persistent low back pain from January to December 2023. We assessed the existence of neuropathic pain using the Douleur Neuropathique 4 (DN4) questionnaire. We evaluated pain severity using the Visual Analogue Scale (VAS). We categorized the patients into three groups: non-operated, operated without stabilization, and operated with stabilization.
Results:
The patients had a mean age of 45.09 ± 14.28 years, with 57.6% being male. A DN4 score of > 4 indicated that neuropathic pain was present in more than half (51.2%) of the patients. The prevalence of neuropathic pain was 32.8% in the non-operated cohort, 67.3% in the operated cohort without stabilization, and 85% in the operated cohort with stabilization. Age exhibited a positive link with neuropathic pain score (r = 0.16, p
Effect of superplastic deformation on changes in the structure and properties of high-speed steels of various metallurgical nature
Authors: Kutepov S.N. , Klementyev D.S. , Gvozdev A.E. , Gadalov V.N.
Published: February 2025

The article examines the effect of superplastic deformation on changes in the structure and properties of high-speed steels of grades R6M5 and 10R6M5-MP of various metallurgical nature. It has been established that, regardless of the method of production and the degree of deformation, steel has a homogeneous structure — sorbitollike perlite and carbides. It was revealed that carbides have mainly a rounded shape, some have an angular shape. It is shown that for steel R6M5, the optimal temperature of superplasticity is 797,3 °С, and the corresponding optimal deformation rate is 0,03015 s–1. In 10R6M5-MP powder steel, the optimal temperature of superplasticity is 796,6 °С, and the corresponding optimal deformation rate is 0,4827 s–1.
Predição da Propensão à Cardiopatia Atrial e Fibrilação Atrial Paroxística em Pacientes com Acidente Vascular Cerebral Embólico de Origem Indeterminada (ESUS)
Authors: Kishk Ahmed , Abdeldayem Mohamed E. , Khalil Mohamed A. , Elbarbary Mohammed
Published: February 2025

Resumo Fundamento Ainda há uma população significativa de pacientes com acidente vascular cerebral embólico de origem indeterminada (ESUS) cuja causa específica atribuível ao acidente vascular cerebral permanece desconhecida. Objetivos Nossa pesquisa teve como objetivo avaliar parâmetros clínicos, eletrocardiográficos, laboratoriais e ecocardiográficos que podem predizer a propensão à fibrilação atrial paroxística (FAP). Métodos Inscrevemos setenta e cinco pacientes ESUS que estavam em ritmo sinusal no momento do diagnóstico de acidente vascular cerebral para serem submetidos a monitoramento Holter de 7 dias no hospital, teste para Pro-BNP e um exame ecocardiográfico padrão. Para análise estatística, um valor de P < 0,05 foi considerado significativo. Resultados A idade média dos 75 pacientes ESUS foi de 58 anos. 60% dos pacientes eram do sexo masculino, e a condição concomitante mais prevalente foi hipertensão (53,3%). Quarenta pacientes tinham cardiopatia atrial, e 15 pacientes tiveram episódios de FAP. Hipertensão e E/e- > 12 foram preditores independentes de cardiopatia atrial, com valores de p de 0,001 e 0,02, respectivamente. Em pacientes com cardiopatia atrial, foi realizada análise de regressão multivariável; velocidade de força terminal da onda P na derivação V (PTFV) > 5000 mV.ms, índice de volume do átrio esquerdo > 34 ml/m2 e fração de ejeção < 45% foram preditores independentes significativos de FA com valores de p significativos de 0,001, < 0,001 e 0,001, respectivamente. Conclusões Em pacientes ESUS, a cardiopatia atrial foi prevalente. Hipertensão e uma razão E/e- maior que 12 foram preditores independentes para ela. A análise de regressão multivariável identificou PTFV1 > 5000 mV.ms, índice de volume de AE > 34 ml/m2 e fração de ejeção < 45% como preditores independentes para fibrilação atrial de início recente.
Eficácia e Segurança do Isolamento Adjuvante da Parede Posterior em Pacientes com Fibrilação Atrial Persistente: Uma Revisão Sistemática e Metanálise
Authors: Novaes João Vitor Levindo Coelho , Brasil David de Pádua , Faria Flavia Maria de Freitas , Garcia Isadora Soares Bicalho , Pimenta Camila Ribeiro , Guimarães Nathalia Sernizon , Malachias Marcus Vinicius Bolivar
Published: February 2025

Resumo Fundamento Em pacientes com fibrilação atrial (FA) persistente, a realização do isolamento da parede posterior (IPP) além do isolamento das veias pulmonares (IVP) é controversa. Objetivo Comparar IVP mais IPP versus IVP exclusivo em pacientes com FA persistente. Métodos Trata-se de uma revisão sistemática conduzida nas bases de dados PubMed (MEDLINE), Embase, LILACS, CENTRAL (Cochrane Library), e Clinicaltrials.gov por ensaios clínicos randomizados comparando IVP + IPP e IVP exclusivo e FA persistente. Os desfechos foram (i) recorrência de FA; (ii) recorrência de arritmias atriais, isto é, FA, taquicardia atrial, ou flutter atrial); (iii) complicações clínicas importantes (isto é, derrame ou tamponamento pericárdico; disfunção do nó sinusal ou fístula atrioesofágica); (iv) tempo médio de ablação. O risco de viés e a qualidade da evidência foram avaliados usando a ferramenta Cochrane de avaliação de risco de viés (RoB 2.0) e o GRADE, respectivamente. A significância estatística foi estabelecida em 5%, e análises por subgrupos e de sensibilidade foram realizadas. Resultados Foram incluídos oito estudos e 1119 pacientes, dos quais 561 se submeteram a IVP+IPP. Durante o seguimento (12-24 meses), a recorrência de FA foi significativamente diminuída com IPP adjuvante (RR 0,66; IC 95%; 0,44-0,98). O composto de arritmias atriais recorrentes não difere significativamente (RR 0,83, IC 95% 0,65- 1,06). As complicações clínicas maiores (RR 0,81, IC95% 0,42-1,58) foram similares, e o IVP exclusivo foi associado a um tempo médio mais curto de procedimento (diferença média -23,37 minutos, IC 95% -30,23, -16,50). Conclusão O IPP adjuvante parece efetivo em melhorar FA recorrente, mas não a recorrência de todas as arritmias atriais. O tempo de procedimento foi mais longo com IVP + IPP sem mudança significativa na segurança global. Mais estudos são necessários para investigar os benefícios em longo prazo.
THE NATURAL VEGETABLE POWDERS EFFECT ON THE YOGURT QUALITY
Authors: Bakin Igor , Korchuganova Anna , Bychkov Dmitriy , Mustafina Anna
Published: February 2025

The prospects for the enrichment of yoghurts with vegetable powders have been studied. The purpose of research is to study the possibility of enriching yogurt with biologically active substances of plant powders, to develop the formulation of the product and to study microbiological, organoleptic and physico-chemical parameters. Tasks: to develop recipes for yogurt with vegetable powders; to conduct a comparative assessment of the quality of yoghurts with different dosages of the introduced components; to investigate organoleptic, physico-chemical indicators of quality and safety. The objects of the study were samples of yogurt made by the tank method with thermophilic starters YF-L812, with the addition of dry powders ((Solanum lycopersicum), (Ocimum basilicum), (T. caerulea (L.) Ser.)). Samples were produced at Yurginsky Gormolzavod LLC, Yurga, Kemerovo Region. Yogurt quality indicators were determined according to GOST 31981-2013, organoleptic indicators – according to GOST R ISO 22935-2-2011. A sensory scoring scale were developed. Statistical evaluation was carried out for three replications, at a significance level of 95 % (p < 0.05). Fortified yogurt formulations were developed. The data on organoleptic and physico-chemical parameters are presented. It was found that enrichment (from 2.51 to 5.0 g per 1 kg of product) with a mixture of powders changes the flavor composition and improves organoleptic evaluations. Samples with a mixture of tomato and fenugreek powders had the best results. It was found that when using the product with tomato additives in 400 g, the proportion of the physiological norm of the daily requirement for vitamins was the largest (C – 70 %, A – 11.52, B1 (thiamine) – 25.3 %). No significant difference (p > 0.05) in terms of physicochemical parameters (proportion of protein, fat, dry matter, dry skimmed milk residue) was found between the enriched samples and the control. Compliance of the samples with the safety requirements, TR TS 021/2011, 033/2013 and GOST 31981 for microbiological indicators was established. The developed samples of yoghurts are recommended to dairy industry enterprises as enriched products with natural herbal supplements.
CLINICAL AND ECHOCARDIOGRAPHIC CHARACTERISTICS OF CARDIORENAL SYNDROME IN DOGS WITH BICUSPID VALVE ENDOCARDIOSIS
Authors: Vatnikov Yuriy , Vilkovyskiy Il'ya , Schurov Igor' , Sotnikova Elena , Byakhova Varvara , Petrukhina Olesya , Rudenko Andrey
Published: February 2025

The aim of the study is to investigate clinical and echocardiographic parameters in dogs with the development of cardiorenal syndrome as a complication of bicuspid valve endocardiosis. The study was conducted on 22 healthy dogs and 55 dogs with bicuspid valve endocardiosis complicated by cardiorenal syndrome. The sick dogs were divided into two groups: the first group was free from cardiorenal complications (n = 24), the second group was with cardiorenal syndrome (n = 31). It was shown that cardiorenal syndrome in dogs can develop as a complication of congestive left ventricular heart failure in left atrioventricular valve endocardiosis. In this case, cardiorenal syndrome is a marker of a more severe course of congestive left ventricular heart failure in dogs, which, in turn, initiates a decrease in renal function. Clinically, cardiorenal syndrome in dogs with endocardiosis is manifested by dyspnea, tachypnea during rest and sleep, tachycardia, systemic arterial hypertension and hypothermia. Echocardiographic studies in dogs with cardiorenal syndrome revealed signs of dilation of the pulmonary vein by 2.25 times (p < 0.001) and the left atrium by 1.66 times (p < 0.001), a decrease in longitudinal contractility of the left myocardium by 1.5 times (p < 0.05) and the right ventricle by 1.25 times (p < 0.05) compared to healthy dogs. In addition, in dogs with cardiorenal syndrome, a restrictive type of diastolic dysfunction of the heart was verified (an increase in peak E by 1.85 times (p < 0.001) and a decrease in peak A of transmitral blood flow by 1.5 times (p < 0.001), a decrease in the time of isovolumic relaxation by 1.74 times (p < 0.001) compared with healthy animals), as well as pronounced eccentric hypertrophy of the left ventricle (an increase in the end-diastolic size of the left ventricle by 1.38 times (p < 0.001) compared with healthy animals).
PRECLINICAL STUDY OF A POLYVALENT VACCINE AGAINST BOVINE MASTITIS
Authors: Makhmutov Aidar , Spiridonov Gennadiy , Dupleva Liliya , Husainov Il'nur , Zaripov Ayrat
Published: February 2025

The aim of the study is a preclinical study of a polyvalent vaccine against bovine mastitis. The vaccine is made on the basis of inactivated bacteria of the strains Streptococcus uberis 3T-SD, Staphylococcus aureus 18-C, E. coli 19-SD. 6 % aluminum hydroxide gel was used as an adjuvant. During the preclinical study, the physicochemical characteristics of the vaccine, the completeness of inactivation and sterility, harmlessness, pyrogenicity, antigenic activity were studied, as well as the optimal vaccination dose of the vaccine for cows was determined and the harmlessness of a double administration of the vaccine in prophylactic and increased doses was examined. The polyvalent vaccine against mastitis is sterile, harmless for laboratory (white mice) and target (cows) animals. Its double administration promotes the synthesis of specific antibodies in the blood serum of rabbits to the Staphylococcus aureus antigen in the titer of 853.33 ± 261.28, to the Streptococcus uberis and E. coli antigens in the titers of 640.0 ± 0.0. The optimal vaccination dose of the preparation for target animals was determined on 3 groups of cows with 5 heads in each. The doses tested were 3; 5 and 7 cm3. The optimal vaccination dose of the vaccine for cows is 5 cm3 with its double administration with an interval of 14 days. After double administration of the vaccine in prophylactic and increased doses, the animals maintain a normal physiological state. They have no signs of pathological local and systemic reactions. Animals move actively, willingly take food and water, their general body temperature remains within the physiological norm.
BIOTECHNOLOGICAL METHOD OF DAIRY RAW MATERIAL MODIFICATION TO CREATE SPORTS NUTRITION PRODUCTS
Authors: Mironova Irina , Slinkin Artem , Kanareikina Svetlana , Krupina Oksana , Khabibullin Ilmir
Published: February 2025

The aim of research is to study the effect of introducing the selenium-containing additive Sel-Plex into the diet of dairy mares on the quality indicators of mare's milk as a raw material for the production of food products based on it. Objectives: to introduce a selenium-containing supplement into the horses’ diet; to determine the physicochemical quality indicators of mare’s milk; to determine the selenium content in the milk samples being studied, and the microelement and vitamin composition of the modified milk. The object of the study is mare's milk from dairy mares of the Bashkir breed. The mares received the main and modified diets. The main diet is based on generally accepted data, the modified diet is supplemented with the Sel-Plex preparation to the main diet at the rate of 1 g per 100 kg of live weight. Milk quality indicators were determined using standard methods accepted in research practice, focusing on TR CU 033/2013 and TR CU 021/2011. Titratable acidity was determined according to GOST 3624, mass fraction of protein – according to GOST 34354, fat – according to GOST 5867, density according to GOST 3625, SNF – according to GOST R 54761, lactose – according to GOST 34304, calcium – according to GOST R 55331, phosphorus – according to GOST 31980. The content of toxic elements and selenium was determined by atomic spectrometry, vitamins – by chromatographic methods. Data processing was carried out using generally accepted statistical methods. The use of biological modification of raw mare's milk contributed to the improvement of the qualitative composition of mare's milk. Milk obtained from animals receiving selenium in organic form was tested for vitamins, microelements, as well as physicochemical indicators. The selenium content in it increased by 36.83 % at the end of the experiment. Mare's milk enriched with selenium in organic form can be used as a raw material for the production of specialized products, including sports nutrition.
IDENTIFICATION OF THE DRIVING FORCE BEHIND THE EXTRACTION OF WATER-SOLUBLE SUBSTANCES FROM PERSIMMON PULP
Authors: Makarov Artem , Aleksanyan Igor , Nugmanov Albert Hamed-Harisovich , Osmolovskiy Pavel , Bakin Igor
Published: February 2025

The aim of the study is to determine the driving force of the process of extraction of water-soluble substances from persimmon pulp based on information about its kinetics and hydrodynamics, as well as to study the statics of this operation, in particular the distribution coefficients of the equilibrium concentrations of the extracted substance in both phases. Tasks: to study the statistical patterns of the operation of extraction of water-soluble substances from persimmon pulp in order to determine the distribution coefficients of the equilibrium concentrations of the extracted substance in both phases, which determines the driving force of the process; to identify the driving force of the process of extraction of water-soluble substances from persimmon pulp without the use of ultrasound based on information about the kinetics and hydrodynamics of the studied mass transfer; to identify the driving force of the process of extraction of water-soluble substances from persimmon pulp using ultrasound based on information about the kinetics and hydrodynamics of the studied mass transfer. The object of the study is persimmon fruits of the Hyakume, Sharon, Korolek varieties, grown in the south of the Russian Federation, in particular in the Republic of Crimea in the National Scientific Center of the Russian Academy of Sciences (Nikitsky Botanical Garden). The obtained data on the identification of kinetic patterns of extraction of components soluble in water from persimmon pulp, as well as on the determination of the distribution coefficient of equilibrium concentrations of the extracted substance in both phases made it possible to identify the rational duration of extraction both with and without exposure to ultrasound, and to obtain mathematical dependencies of the driving force of the process, knowledge of which is necessary for constructing a mathematical model of mass transfer.
VETERINARY AND SANITARY EXAMINATION OF SIBERIAN ROE DEER MEAT (CAPREOLUS PYGARGUS (PALLAS, 1771) AND REINDER (RANGIFER TARANDUS) OF YAKUTIA
Authors: Tatarinova zinaida
Published: February 2025

The objective of research is to conduct an examination of the meat of Siberian roe deer and reindeer to identify possible threats to human health, to determine the suitability of roe deer and venison for human consumption in accordance with the requirements of regulatory documents. Objectives: to study the organoleptic properties of roe deer and venison; to conduct microscopic, physicochemical studies of meat; to conduct a luminescent analysis; to study the radioactive background of meat; to determine the content of nitrates in meat samples. Based on the results of laboratory studies, it was established that, according to organoleptic properties, roe deer and reindeer meat belongs to the fresh category. Roe deer meat has a bright red drying crust, the structure of muscle fibers is thin, bright red, reindeer meat has a dark red drying crust, muscle fibers are dark red. Each type of meat has a certain specific smell and taste. In physicochemical studies (by reaction with copper sulfate, peroxidase, Nessler reagent, pH value), roe deer and venison meat were classified as fresh and corresponded to the indicators of healthy animals. The data of luminescent and bacterioscopic analysis also indicate the freshness and safety of meat samples. The value of the radiation background of roe deer meat is 0.17 μSv/h, venison – 0.4 μSv/h with a norm of 0.5 μSv/h. The content of nitrates is within the standardized indicators: roe deer meat – 192 mg/kg; venison – 152 mg/kg (MPC – 200 mg/kg). The conducted veterinary and sanitary studies indicate the freshness and good quality of roe deer and venison meat samples, which allows people to eat meat without restrictions.
PROSPECTS OF HERMETIA ILLUCENS FLY BREEDING TO SOLVE THE PROBLEMS OF PROTEIN NUTRITION IN ORGANIC AGRICULTURE
Authors: Samokish Nikolay , Skripkin Valentin , Kvochko Andrey , Seryi Nikolay , Rastovarov Evgeniy
Published: February 2025

The objective of the study is to determine the nutritional value of the black soldier fly at all stages of its development cycle, as well as to predict the efficiency of feeding fly processing products to egg-producing quails by calculating rations with the inclusion of the most nutritionally valuable raw materials. Objectives: study of the nutritional value of the experimental material; development of the experiment scheme; calculation of rations according to the experimental scheme using the KormOptima software. The studies were conducted in the scientific laboratory Feed and Metabolism of the Stavropol State Agrarian University. At the first stage, analyzes were carried out to determine the nutritional value of the fly at different stages of its development from larva to dead bodies. Quality indicators were determined in accordance with approved methods. When drawing up the experiment scheme for groups of egg-producing quails, 1 and 5 % of larvae and 1 and 5 % of prepupa were added to the main ration, thereby forming 5 groups of quails, including a control group. The rations of the control and experimental groups of quails aged 55 days were calculated in accordance with the standard of GOST 28460-2014. Egg-producing quails were selected using the method of pairs of analogues with 35 heads per group. The obtained protein product turned out to be highly nutritious: crude protein – 40–45 %, crude fat – up to 42 %, this provides high energy value, which is beneficial for balancing poultry rations. The amino acid composition of the black soldier fly larvae corresponds to the amino acid profile of animal feed, especially in terms of the high content of limiting amino acids. Based on the obtained nutritional value of the experimental samples, rations for egg-producing quails were calculated. When introducing 1 and 5 % of larvae into the diet, the cost decreased by 0.58 and 3.95 %, respectively, compared to the control. When introducing prepupa into the diet at 1 and 5 %, the price decreased by 0.75 and 3.77 %, respectively.
Pendekatan Discrete Event Simulation untuk Peningkatan Sistem Produksi Pada Perishable product
Authors: Jamil Nofal , Pulungan Muhammad Almaududi , Yastica Tiara Verita
Published: February 2025

Bottlenecks in perishable products processing have significantly decrease the number of sweet potato paste production at PT. XYZ, which have lead to the decrease of more than 23.44% in the fulfillment of the number of demand and result in 2023. These problems are also caused by suboptimal production planning, lack of efficiency in the production process, the occurrence of raw material bottlenecks in the production process, suboptimal resource management and the occurrence of many rejections in the finished good. This study aims to overcome bottlenecks that occur in order to increase the amount of sweet potato paste production. The methodology of this study uses the discrete event simulation approach. This study applies a confidence level of 95% in the existing simulation model. Of the 20 scenario models that have been built, the best four models were further evaluated based on the output and cost aspects. The best of the four is scenario model 13 with the addition of 1 shift in the entire production process, namely the sorting process to the outer packing process with the addition of 105 workers.  This scenario produced 1,274,527 kg of products for 10 months and a percentage increase in the amount of output of 72.74%, gross profit value of IDR 4,016,084,955.50 and marginal profit value of IDR 778.82 with additional direct labor costs of IDR 2,199,145,960 for 10 months and investment costs of IDR 0.

Keywords – Bottleneck, Discrete Event Simulation, Gross Profit, Marginal Profit, Perishable product.
Karakteristik Kimia, Sifat Fungsional, dan Prediksi Indeks Glikemik Tepung Komposit Berbasis Hanjeli (Coix lacryma-Jobi) Termodifikasi
Authors: Adelina Nadya Mara , Aziz Lukman , Fauziyah A’immatul , Mevera Khezia , Salmatyanti Nesia Odnikana
Published: February 2025

In 2021, Indonesia ranked 5th globally for the highest number of diabetes cases, primarily due to excessive consumption of high-glycemic index foods. The glycemic index is influenced by fiber, minerals, bioactive compounds, and starch modification. This study aims to determine the optimal formulation of Heat Moisture Treatment (HMT) modified hanjeli flour, dragon fruit peel flour, and cashew nut flour to obtain composite flour with the lowest predicted glycemic index. The physical, functional, and chemical properties of the flour were also analyzed. A Completely Randomized Design (CRD) with one factor and five treatments was used. Composite flour was prepared by mixing dried ingredients using a food dehydrator. Results showed that sample F5 (45% dragon fruit peel flour) had the highest Water Holding Capacity (WHC) and Oil Holding Capacity (OHC). Fiber content, ash content, total phenolics, and resistant starch increased with the higher ratio of dragon fruit peel flour, whereas rapid digestible starch (RDS) and slow digestible starch (SDS) decreased as the proportion of modified hanjeli flour decreased. Sample F4 (50% modified hanjeli flour, 35% dragon fruit peel flour, and 15% cashew nut flour) had the lowest predicted glycemic index (40.53), making it a promising ingredient for low-glycemic index foods.

Keywords – Bioactive Compounds, Diabetes, Fiber Content, Heat Moisture Treatment, Modified Starch.
Penghilangan Logam Berat Dari Lindi Tempat Pembuangan Sampah Menggunakan Tanaman Akuatik
Authors: Dolhan Mimi Malisa , Bain Noor Farahin , Arbaan Nur Shuhada
Published: February 2025

Landfill leachate, a contaminated liquid produced from rainwater passing through waste materials, presents serious environmental risks by polluting soil and water sources. This study examines the potential of water spinach (WS) (Ipomoea aquatica), water hyacinth (WH) (Eichhornia crassipes), and marsh pennywort (MP) (Hydrocotyle umbellata) to remove heavy metals from landfill leachateIt evaluates levels of heavy metals such as zinc (Zn), copper (Cu), and iron (Fe) to assess the effectiveness of pollutant removal. Leachates from landfills were distributed among four basins over a period of 28 days; (Basin 1 – control, basin 2 – water hyacinth, basin 3 – water spinach, basin 4 – marsh pennywort) and each basin underwent testing with different retention times. The results proved substantial decrease in all  of the selected heavy metals (Zn, Cu and Fe) levels after treatment with WH, WS and MP. All the aquatic plants demonstrate an ability to absorb heavy metals, leading to lowered concentrations in the leachate. These findings highlight WH, WS and MP promise as  phytoremediation tools for managing landfill leachate contamination that can help to combat pollution and safeguard water resources. This project aims to compare how effectively WS, WH and MP, with various exposure times, can eliminate heavy metals.
Efisiensi Alokatif Dan Faktor-Faktor Produksi Usahatani Kopi Robusta Di Desa Jugo Kecamatan Mojo Kabupaten Kediri
Authors: Nur Dianasari Melinda , Nurul Choirina Vifi , Maharani Navita , Setiyadi Heru
Published: February 2025

Tujuan penelitian ini adalah untuk mengetahui efisiensi alokatif dan faktor produksi yang mempengaruhi usahatani Kopi Robusta di Desa Jugo Kecamatan Mojo Kabupaten Kediri. Metode analisis data yang digunakan yaitu analisis regresi linier berganda dengan menggunakan fungsi Cobb-Douglass. Hasil penelitian menunjukkan bahwa faktor yang berpengaruh pada produksi usahatani Kopi Robusta adalah faktor produksi bibit dan tenaga kerja. Pada tingkat harga yang berlaku saat penelitian penggunaan faktor - faktor produksi pada usahatani Kopi Robusta semuanya belum efisien. Bibit dan Tenaga kerja penggunaannya terlalu sedikit sehingga perlu adanya penambahan.
Tataniaga Komoditas Padi (Oryza Sativa L.) Di Kecamatan Papar Kabupaten Kediri
Authors: Amirroh Khoirunnisa Siti , Winahyu Nastiti , Puji Astoko Endro
Published: February 2025

The aim of this research is to determine marketing channels and analyze farmer's share of rice commodities in Papar District. This research uses analysis of costs, margins, farmer's share, and the ratio of profit per trading cost. The research results show that the dynamics of rice trading in Papar District involve several institutions that have an important role in creating an efficient supply chain. Farmers as primary producers interact with various institutions, such as farmers, middlemen, collectors, and retail agents, who are interconnected to meet consumer needs. The dominance of the use of certain marketing channels reflects the adaptation of business actors to fluctuating market demand. Farmers get the largest share if they can cut marketing channels. These findings raise interesting questions about how changes in supply chains can impact farmers' sustainability and welfare, as well as what strategies need to be adopted to optimize profits without compromising rice accessibility for consumers. Recognizing the importance of relationships between all institutions in the trading system, this research opens up space for deeper discussions about the agribusiness system and the challenges that exist at the local level.
Analisis Pendapatan Dan Kelayakan Usahatani Ubi Kayu Di Kabupaten Wonogiri
Authors: Fitria Cahyaningsih Anggi , Septina Azizi Ernes , Henggar Jaya Gigieh
Published: February 2025

Ubi kayu merupakan salah satu komoditas pertanian yang memiliki banyak kegunaan baik dalam pemenuhan konsumsi serta produksi bagi industri berbahan baku ubi kayu. Kabupaten Wonogiri merupakan daerah dengan tingkat produksi tertinggi di Jawa Tengah. Penelitian ini bertujuan untuk: 1) menganalisis biaya dan pendapatan usahatani ubi kayu di Kabupaten Wonogiri serta 2) menganalisis kelayakan usahatani ubi kayu di Kabupaten Wonogiri. Metode penentuan daerah pada Kabupaten Wonogiri menggunakan stratified random sampling berdasarkan stratifikasi produktivitas ubi kayu tinggi dan produktivitas ubi kayu rendah, sehingga terpilih dua kecamatan yaitu kecamatan Ngadirojo dan Kecamatan Jatiroto. Penentuan sampling menggunakan quota sampling dan diperoleh jumlah responden sebanyak 60 petani ubi kayu. Data primer dan data sekunder digunakan dalam penelitian ini yang diambil melalui observasi, wawancara dengan kuisioner, pencatatan dan dokumentasi. Metode analisis data menggunakan analisis biaya dan pendapatan usahatani serta analisis R/C ratio dan analisis Break Event Point (BEP) untuk mengetahui kelayakan usahatani. Hasil penelitian menunjukkan besarnya biaya usahatani ubi kayu di Kabupaten Wonogiri sebesar Rp 1.876.960,64 /Ha/MT dan rata-rata besarnya penerimaan usahatani ubi kayu yaitu Rp 6.363.846,95/Ha/MT sehingga diperoleh besarnya pendapatan usahatani ubi kayu di Kabupaten Wonogiri sebesar Rp 4.486.886,31. Analisis R/C Ratio sebesar 3,39 menunjukkan bahwa usahatani ubi kayu di Kabupaten Wonogiri secara ekonomi sudah efisien dan sudah memberikan keuntungan bagi petani. Rata-rata produksi ubi kayu di atas BEP unit (6.920,87 kg > 538,98 kg) dan harga jual diatas BEP harga (Rp 919,51 > Rp 271,20) sehingga usahatani ubi kayu di Kabupaten Wonogiri memberikan keuntungan dan layak untuk diusahakan.
ANALISIS KONDISI JALAN BERDASARKAN NILAI IRI (INTERNATIONAL ROUGNESS INDEX) (Studi Kasus: JL IR H Juanda – JL Anoa Kabupaten Tegal)
Authors: Putri Zania Septiani , Berlianindya Fiarentina , Ramadhan Taufik , Fahriza Dawam , Hadi Suprapto
Published: February 2025

Jalan merupakan infrastruktur bidang transportasi yang digunakan sebagai prasarana lalu lintas, semakin bagus kondisi jalan pada suatu wilayah maka dapat dikatakan wilayah tersebut mempunyai tingkat kesejahteraan yang tinggi namun kurangnya informasi dan data base kondisi jalan menjadikan beberapa ruas jalan yang rusak tidak dilakukan penanganan lebih lanjut. Tujuan penelitian ini adalah melakukan penilaian kondisi jalan dimana nilai kondisi jalan ini nantinya dijadikan acuan untuk menentukan jenis program evaluasi yang harus dilakukan, apakah itu program peningkatan, pemeliharaan berkala atau pemeliharaan rutin. Manfaat yang akan didapat pada penelitian ini adalah dapat digunakan sebagai bahan acuan bagi pemerintah dan pihak pengelola jalan dalam melakukan penanganan kerusakan jalan dan juga dapat dijadikan sebagai kajian transportasi terkait kerusakan jalan bagi para pembaca. Penulis melakukan analisis kondisi jalan menggunakan mobil hawkeye 2000 milik PKTJ Tegal pada ruas jalan Ir H Juanda sampai ruas jalan Anoa sebesar 2,67 km didapatkan rata rata IRI sebesar 3,21% dengan panjang jalan dalam kategori baik sebesar 1990 pada jalur selatan ke utara dan rata rata IRI sebesar 2,5% dengan Panjang jalan dalam kategori baik sebesar 1890 meter. Rekomendasi penanganan yang tepat berdasarkan nilai IRI adalah dilakukan pemeliharaan secara rutin dan berkala yang sesuai denga umur teknis jalan agar tidak terjadi kerusakan yang parah yang menyebabkan biaya penanganan akan semakin besar
NORMALISASI LANSKAP KORIDOR SUNGAI MATI CITARUM DENGAN ANALISIS HIDROLOGI (Studi Kasus: Desa Rancamanyar, Kabupaten Bandung)
Authors: Izzati Husna , Rustandi Iing
Published: February 2025

Sungai Citarum merupakan sungai utama di Jawa Barat yang memiliki fungsi ekologis, ekonomis, dan hidrologis. Posisi Daerah Aliran Sungai (DAS) Citarum yang dekat dengan pemukiman penduduk dan berbagai sektor industri (rumah tangga, pertanian, peternakan, dan industri tekstil), berakibat  rusaknya ekosistem DAS Citarum. Limbah pabrik, sedimentasi, penumpukan sampah, pembukaan lahan tepi sungai, dan kurangnya kepedulian masyarakat, merupakan beberapa penyebab pencemaran DAS Citarum. Upaya penanggulangan DAS berupa pelurusan badan sungai untuk mengurangi penumpukan polutan, pernah dilakukan oleh Balai Besar Wilayah Sungai (BBWS) Citarum pada tahun 1994 dan 2011. Dampak dari kegiatan ini adalah munculnya badan sungai lama yang tidak teraliri, dikenal dengan istilah sungai mati  atau oxbow. Permasalahan yang timbul pada oxbow di antaranya genangan air, buruknya sanitasi, pengambilalihan lahan tanpa izin, hingga kecenderungan konflik sosial. Penelitian ini bertujuan untuk mengidentifikasi permasalahan hidrologi lanskap oxbow khususnya di Rancamanyar, Baleendah, Kabupaten Bandung. Menggunakan metode campuran, data kualitatif didapatkan dengan teknik observasi dan wawancara, sedangkan data kuantitatif menggunakan data curah hujan, debit aliran, dan data tampungan oxbow. Analisis data dilakukan dengan metode deskriptif dan pengujian dengan menggunakan formula dan perangkat lunak. Hasil dari penelitian ditemukan bahwa sumber aliran yang masuk ke oxbow dan tingkat curah hujan berpengaruh terhadap siklus banjir di area sekitar Oxbow Rancamanyar. Dengan perhitungan perkiraan debit banjir rencana, perhitungan debit inflow dan outflow, dan daya tampung maksimal oxbow, didapatkan bentuk bentang ideal dari penampang oxbow yang digunakan sebagai dasar dalam normalisasi lanskap Oxbow Rancamanyar.
PENGARUH LIGHT SHELF STATIS TERHADAP KINERJA PENCAHAYAAN ALAMI KANTOR OPEN-PLAN
Authors: Hasya Astrini Hadina , Nastiti Ratna Andriani , Rachman R. Ayu Firdausi Novira , Dewi Riza Septriana , Artito Ihza Rangga
Published: February 2025

Kantor dengan sistem open-plan merupakan bangunan yang populer saat ini dengan kompleksitas aktivitas dan kebutuhan pengguna. Keuntungannya yang hemat tempat dan membuat kesan luas menjadikan kantor open-plan digemari. Aktivitas utama kantor sebagai tempat bekerja membutuhkan pencahayaan alami yang optimal dalam mengakomodir seluruh kegiatan utamanya pada jam kantor di siang hari. Penelitian ini merupakan penelitian kuasi experimental dengan mengevaluasi kinerja pencahayaan alami bangunan kantor. Pertimbangan bangunan kantor yang dipilih yakni berdasarkan kriteria kantor open-plan pada umumnya. Permasalahan pencahayaan alami yang tidak merata ke dalam ruang kantor menuntut kebutuhan sistem untuk peningkatan kinerja pencahayaan alami. Penggunan lightshelf sebagai sistem pembayang alami diusulkan sebagai salah satu alternatif peningkatan kinerja pencahayaan alami yang di simulasikan secara komputasi menggunakan Ecotect dengan plug-in Radiance. Teknik pengumpulan data dilakukan  melalui permodelan simulasi komputer dan studi literatur.  Diharapkan hasil penelitian ini dapat menambah wawasan dan digunakan sebagai alternatif sistem pembayang matahari.
KOMPARASI ANALISIS BANGUNAN PENGAMAN LERENG MENGGUNAKAN METODE LOAD RESISTANCE FACTOR DESIGN DAN ALLOWABLE STRESS DESIGN
Authors: Harjanto Furqaan , Rofiyantama Dega , Maharani Mentari Putri
Published: February 2025

Dinding penahan tanah merupakan struktur penting dalam konstruksi sipil yang digunakan untuk menahan tekanan tanah dan air. Dua metode umum yang digunakan untuk analisis dinding penahan tanah adalah metode Load and Resistance Factor Design (LRFD) dan Allowable Stress Design (ASD). LRFD didasarkan pada prinsip keseimbangan probabilistik dan mempertimbangkan faktor keamanan yang eksplisit untuk memastikan bahwa kapasitas struktur lebih besar dari beban yang mungkin terjadi, sedangkan ASD didasarkan pada prinsip bahwa tegangan yang bekerja pada struktur tidak boleh melebihi tegangan yang diizinkan untuk material dan lebih sederhana daripada metode LRFD, tetapi tidak mempertimbangkan faktor keamanan secara eksplisit dan tidak memperhitungkan ketidakpastian dalam material, beban, dan analisis. Dengan adanya perbedaan pendekatan dalam analisis LRFD dan ASD, penelitian ini bertujuan untuk membandingkan hasil analisis dengan pendekatan LRFD dan ASD pada kasus dinding penahan tanah tipe secant pile pada lereng sungai X yang dimana analisis awal menggunakan pendekatan ASD. Data sekunder berupa data tanah dan potongan melintang lereng sungai didapatkan dari konsultan perencanaan sebelumnya, lalu analisis dilakukan dengan software GEO5. Model awal dibuat terlebih dahulu dengan parameter yang sama dengan perencanaan sebelumnya agar memberikan hasil kebutuhan penetrasi, displacement dan gaya dalam yang sama dengan perencanaan dari konsultan perencana. Model yang telah sama dalam hasil analisis tersebut akan digunakan sebagai model analisis untuk pendekatan LRFD dan hasil analisis pada model LRFD tersebut akan dibandingkan dengan model analisis pada pendekatan ASD. Berdasarkan dari hasil analisis LRFD pada kondisi batas Kuat, didapatkan metode LRFD memberikan kedalaman penetrasi 21.7% lebih besar daripada ASD, gaya moment 40% lebih besar dari ASD dan gaya geser 7.8% lebih besar dari ASD. Pendekatan lebih detail perlu dilakukan pada kondisi batas lain seperti Layan dan Ekstrim agar dapat memberikan hasil perbandingan yang lebih optimal
PERENCANAAN JARINGAN AIR BERSIH KELURAHAN TANJUNG MAS KECAMATAN SEMARANG UTARA
Authors: Ikhwanudin Ikhwanudin , Ningtyas Octavia Surya , Riana Tasya Dyah Nov , Yudaningrum Farida
Published: February 2025

Air merupakan salah satu sumber pokok kebutuhan yang sangat dibutuhkan oleh makhluk hidup terutama manusia. Biasanya air digunakan untuk kebutuhan sehari-hari, sarana transportasi, maupun kebutuhan untuk keberlangan industri. Kelurahan Tanjung Mas menjadi salah satu daerah pesisir di Kota Semarang. Pertumbuhan kota-kota di wilayah pesisir menyebabkan beberapa permasalahan di masyarakat, terutama kebutuhan air bersih. Sumber mata air dan jaringan pendistribusian air bersih yang kurang memadai disinyalir sebagai faktor utamanya. Tanjung Mas didominasi dari air artesis sebesar 83%. Jumlah penduduk yang juga semakin menurun akibat dari migrasi tiap tahunnnya juga mempengaruhi penggunaan air bersih. Dengan adanya hal tersebut, perlu adanya pengembangan sistem jaringan distribusi dengan bantuan aplikasi Epanet 2.2. Penelitian ini menggunakan metode kuantitatif, Berdasarkan hasil penelitian, kapasitas debit terpasang 14,59 liter/detik masih dapat memenuhi pelanggan. Jumlah kebutuhan air bersih pada kondisi eksisting 2023 yaitu sebesar 6,2 liter/detik dengan jumlah pelanggan sebesar 2.976 SR. Fenomena penurunan jumlah penduduk di Kelurahan Tanjung Mas membuat penelitian ini membuat desain baru dengan mengubah aliran dari IPA Gajah Mungkur ke IPA Kudu.
ANALISIS DAYA DUKUNG TIANG PANCANG STEEL PIPE PILE BERDASARKAN DATA KALENDERING DAN PDA TEST (Studi Kasus: Project Strengthening Jetty 1 & Jetty 2 PLH Existing, Desa Paring Lahung, Kec. Montallat, Kab. Barito Utara, Kalimantan Tengah)
Authors: Kukuh Kurniawan Dwi Sungkono  , Arbianto Reki , Wijayanti Paska , Prasetyo Erwin Aji , Kurniawan Rizal
Published: February 2025

In the field of construction, particularly in geotechnical engineering, uncertainties in foundation design approaches are frequently encountered. Geotechnical uncertainties, especially in foundation design, pose complex challenges due to the heterogeneous nature of soil and data limitations. Dynamic load testing on pile foundations is an alternative method to static load testing in geotechnical engineering for evaluating pile capacity and behavior. The results of this analysis will be compared to the design capacity of pile foundations in the breasting dolphin structure. This study on a breasting dolphin structure utilizing Steel Pipe Pile (SPP) foundations with a diameter 610 mm. PDA tests were conducted on piles at points G6-23, G7-33, G7-38, and G8-46. The study begins with a literature review to comprehend methods and theories related to pile capacity analysis based on calendaring and PDA testing. Calendaring data were analyzed using empirical methods such as the Hiley Formula to estimate the dynamic bearing capacity of each pile. The pile capacity calculated using the Hiley Formula is generally higher than the results obtained from the Case Method and CAPWAP Analysis. The relationship between pile capacity based on the Hiley Formula (calendaring) and the Case Method (PDA test) yielded a linear regression equation of y = 1.0785x - 983.07 with R² = 0.2385, indicating a weak correlation. Meanwhile, the relationship between pile capacity from the Hiley Formula (calendaring) and CAPWAP Analysis (PDA test) resulted in a linear regression equation of y = -0.006x + 2909.8 with R² = 1×10?¹, indicating almost no linear correlation between the two.
AYAT-AYAT HUJAN DALAM PERSPEKTIF WAHBAH AZ-ZUHAILI
Authors: Utami Charissa Myla , Hanum Sarmidah , AM Supriadi
Published: February 2025

Rain is a natural phenomenon that occurs when sea air evaporates and forms clouds in water droplets, then these water droplets fall to the earth. Many people believe that rain can damage the environment around residents, when in fact environmental damage occurs due to human actions. The focus of this research is the Islamic perspective on the meaning of rain in human life in the book of tafsir al-munir by Wahbah az-Zuhaili. By using a thematic study of the meaning of rain. The aim of this research is to avoid misunderstandings about the fall of rain. The results of this research show that rain is a gift from Allah SWT which provides benefits to all living creatures on earth, it can grow plants that produce fruit that can be enjoyed by living creatures on earth and also brings life to barren or dead land. This research only focuses on several letters, namely surah al-Baqarah verse 22, surah al-An'am verse 99, and Fussilat verse 39.
Tantangan Pendidikan Islam Zaman Modern
Authors: Guci Alexander , Nurdin Nurdin , Ajizah Siti
Published: February 2025

In this era, with all the advances in IT and technology as well as changes in social dynamics, it has brought a number of big challenges to the development of Islamic education in Indonesia. Therefore, a deep understanding of these challenges is the main key to implementing effective solutions in aligning Islamic values ​​with the needs of contemporary developments. This research is qualitative research with priority on literature-based critical analysis. The way to conduct this research is to use the narrative method. In critical studies, understanding the context of the challenges of Islamic education in today's exploitative era. This research aims to analyze phenomena or dynamics from an Islamic perspective and strategic efforts to face these challenges. The research results show that the challenges of Islamic education in the current era include (1) The existence of an approach with a worldly orientation, (2) The influence of social media, (3) New approaches in the field of IT-based Islamic education (4) Technology application-based approaches. The strategies and efforts made to answer the challenges of Islamic education in the current era can be formulated as follows: (1) Instilling the values ​​of Islamic education in a comprehensive manner, (2) Approach to Karimah Moral Education in the younger generation, (3) considering the Islamic education system, (4) Improving the quality of teacher resources with an Islamic character, (4) Adapting to applications and technology.