bluuebunny/crossref_metadata_2025 huggingface dataset:
SOCIETIES EXPECTATION AND LIBRARY VALUES: CONTENT ANALYSIS OF THE MOVIE “SMART LIBRARY MAKES SMART PEOPLE"
Authors: Kamaludin Kamaludin
Published: March 2019

Library services are now becoming very important as mandated by law no. 43 the year 2007, in article 14 (1) that library services are primed and oriented to the interests of the user. From that article, the role of librarians is essential in improving services. This study aims to determine the content of the messages available on a movie with title “Smart library makes smart people” especially the signal related to societies’ expectation to the library and the value that can be given by librarian to the users. The method used in this research is using content analysis. The research subject is a documentary movie produced by UPT Balai Informasi Teknologi-LIPI, Bandung, Indonesia, in 2015. The results showed that societies’ expectations could be seen at minute 11:18 of the movie that librarian cannot just expect societies to come to the library, but the library has to come to visit them. One of the vital source of strength, the formation of a nation the role-played by print culture. By reading might get some ideas and how to fulfill the plans. Because reading is a kind of bridge to the future. Other users expect at minute 15:46 that there is new technology, the library must move from old-fashioned to the electronic library. The original problem is about big data, but big data is critical to the future. The value that can be given to the users can be seen at minute 09:45 library has assisted to the provinces in Indonesia more than 600 mobile libraries. For the outer island, there are seven free libraries. In Jakarta, there is a Pusteling, a library and an electronic mobile completed with the laptop and internet. At minute 05:40 it is essential to be a growing library, the librarian must have innovation, creativity, and love of work, if there is no innovation from the librarian, there will be no innovation, no new services, and the library will be stagnant, traditional, no improvement.
EVALUASI PEMANFATAAN DATABASE EBSCO DAN PROQUEST DALAM PENYUSUNAN LAPORAN PENELITIAN DOSEN FAKULTAS EKONOMIKA DAN BISNIS UGM TAHUN 2013-2015 MENGGUNAKAN ANALISIS SITASI
Authors: Maryatun Maryatun , Purwaningsih Heni
Published: March 2019

Evaluation of the use of journal databases containing the same subject area is indispensable for budget efficiency. The evaluation of database utilization is closely related to the availability of information resources as a citation in the preparation of scientific papers. This research is quantitative descriptive research. The research method used is the method of documentation with the object of research citation/bibliography of Lecturer Research report FEB UGM year 2013-2015. The results showed that core journals majoring in Accounting is the Journal of Accounting and Economics with the largest citation frequency of 91 times; Department of Management Academy of Management Journal with citation frequency 65 times; and American Economics Review with a frequency of citation 21 times is the core title of the Department of Economics. In general, the utilization of EBSCO database «Business Source Complete» and ProQuest «ABI/INFORM Complete» as the citation for preparing the research report of FEB UGM lecturer for the period of 2013-2016 has been well utilized. The percentage of e-journal availability in the Business Source Complete database and the ABI/INFORM Collection database cited in the preparation of research report of FEB UGM majoring in Accounting as much as 703 titles (62.8%), Management Department available 655 titles (64.2%) and majors Economics is available 231 titles (44.6%). The «Business Source Complete» EBSCO database and ProQuest «ABI/INFORM Collection» are database aggregators that collect multiple journals from several publishers. In addition, the EBSCO Database «Business Source Complete» provides more economics and business journals than the ProQuest «ABI/INFORM Collection» database. However, ProQuest database «ABI/INFORM Collection» is widely used by Lecturer of Management Department in preparing a research report.
Efektivitas Pencatatan Perkawinan Menurut Undang-Undang Nomor 1 Tahun 1974 (Studi di Kabupaten Polewali Mandar)
Authors: Samsidar Samsidar , Pasamai Syamsuddin , Poernomo Sri Lestari
Published: March 2019

Penelitian ini bertujuan untuk mengetahui efektivitas pencatatan perkawinan di Kabupaten Polewali Mandar. Metode pendekatan yang digunakan dalam penelitian ini adalah metode normatif dan empiris. Lokasi penelitian ialah Kabupaten Polewali Mandar, Provinsi Sulawesi Barat. Hasil penelitian menunujjakn bahwa pencatatan perkawinan di Kabupaten Polewali Mandar pada kenyataannya sudah merupakan aspek merginal di dalam perkawinan. Selain faktor memarginalkan persoalan pencatatan perkawinan, pandangan dan kesadaran hukum masyarakat sudah relatif tinggi mengenai status perkawinan terutama perkawinan di bawah tangan yang tidak memperoleh legitimasi dari kalangan masyarakat awam. Berkenaan dengan pencatatan perkawinan tersebut dikenal dengan istilah nikah resmi yang mana maksud dari nikah resmi itu adalah perkawinan yang tercatat. Akan tetapi di Indonesia ada aturan dalam bentuk undang-undang bahwa setiap perkawinan harus dicatat, dan perkawinan yang tercatat inilah yang dapat disebut perkawinan resmi serta berkekuatan hukum. Sedang perkawinan yang tidak tercatat yang diistilahkan dengan nikah di bawah tangan, berarti tidak resmi dan perkawinan (nikah) tersebut tidak berkekuatan hukum.
Ketentuan-ketentuan TRIPS-Plus dalam Kerangka Perjanjian Perdagangan Bebas
Authors: Sanib Safril Sofwan
Published: March 2019

Tujuan dari penelitian ini adalah untuk menganalisis dan menemukan filosofi Ketentuan TRIPS-Plus di bawah kerangka Perjanjian Perdagangan Bebas Bilateral (Bilateral Free Trade Agreements=BFTA). Penelitian ini adalah penelitian hukum dengan menggunakan pendekatan perundang-undangan, konseptual, dan komparatif. Penelitian ini menemukan, bahwa filosofi dari ketentuan TRIPS-Plus di bawah BFTA adalah untuk menghilangkan standar minimum dan fleksibilitas yang terkandung dalam ketentuan Perjanjian TRIPS WTO yang berdampak pada: (1) pembatasan alasan untuk pengecualian dari invensi yang bisa di patenkan; (2) membatasi penerbitan lisensi wajib; (3) pembatasan ruang lingkup exhaustion of rights dan impor paralel; (4) perpanjangan jangka waktu pemberian paten; (5) kewajiban perlindungan paten untuk perlindungan varietas tanaman; (6) eksklusivitas atas uji data berkenaan dengan produk farmasi dan kimia; (7) perlindungan untuk jenis-jenis merek dagang baru (8) perlindungan yang kuat untuk teknologi digital. Bila negara-negara menyepakati BFTA dengan mitra/partner dagang tentang ketentuan-ketentuan HKI yang mengandung TRIPS-Plus tersebut di atas maka akan menyebabkan negara tersebut tidak dapat menggunakan fleksibilitas yang diberikan oleh perjanjian HKI pada level multilateral (TRIPS Agreement) dan hal tersebut berdampak pada tidak terpenuhinya hak-hak dasar yaitu: hak atas pendidikan, hak atas kesehatan dan akses obat-obatan secara terjangkau dan murah, serta hak atas pangan.
Flight Anxiety Reported from 1986 to 2015
Authors: Grimholt Tine K. , Bonsaksen Tore , Schou-Bredal Inger , Heir Trond , Lerdal Anners , Skogstad Laila , Ekeberg Øivind
Published: March 2019

BACKGROUND: Fear of flying is one of the most common phobias. It hinders people in performing their work and hampers family relations. Even though flight traffic has increased, there are new fears. Valid studies are needed to answer whether there have been changes in the prevalence
of flight anxiety, are there sex differences in relation to fear of flying, use of alcohol, and tranquilizers, which situations cause the most flight anxiety, and whether the above factors have changed compared to a similar study from 1986.METHODS: A questionnaire was distributed
to a representative random sample of the Norwegian population (N = 5500), where 36% answered. To assess flight anxiety across the time period, we used similar instruments to those we used in 1986.RESULTS: The prevalence of an assumed flight phobia decreased from 8% in 1986
to 3% in 2015. The percentage of those reported to never fly had decreased from 5% in 1986 to 0.5% in 2015. There were 11.0% who always used alcohol in 1986 and 7.5% in 2015 and 3% and 2%, respectively, always used tranquillizers. More women reported being afraid of both flying and other situations
compared to men. Turbulence, unknown sounds, and fear of terror attacks caused the most anxiety.DISCUSSION: Flight anxiety still affects a considerable proportion of the Norwegian population and more women than men report that they are afraid of flying. However, in spite of methodology,
people are significantly less afraid of flying than in 1986.Grimholt TK, Bonsaksen T, Schou-Bredal I, Heir T, Lerdal A, Skogstad L, Ekeberg Ø. Flight anxiety reported from 1986 to 2015. Aerosp Med Hum Perform. 2019; 90(4):384–388.
Flight Performance Aspects During Military Helicopter Flights
Authors: Steinman Yuval , van den Oord Marieke H. A. H. , Frings-Dresen Monique H. W. , Sluiter Judith K.
Published: March 2019

INTRODUCTION: A flight is composed of many flight performance aspects. However, not all of these aspects are equally important for the success and safety of a flight. When investigating the influence of a stressor on flight performance, it is important to understand not only
which flight performance aspects are important for the success and the safety of the flight, but also which of these aspects will most likely be affected by reduced alertness.METHOD: A total of 136 helicopter pilots of the Royal Netherlands Air Force (RNLAF) of all qualification
levels were invited to participate in a three-round ranking Delphi study.RESULTS: A total of 41 (30%) helicopter pilots completed the first questionnaire round and 20 (77%) flight instructors completed the ranking round. The top ten skills elements comprised seven nontechnical skills
(NTS), namely, awareness of the environment, decision making, workload management, stress management, planning and coordinating, general knowledge, and basic fitness; and three technical skills (TS), that is, advanced aircraft handling, flight maneuvers and procedures, and abnormal and emergency
procedures. The top three ranked skill elements (awareness of environment, decision making, and workload management) were considered by the flight instructors to be highly influenced by reduced pilot alertness.CONCLUSION: NTS are considered more important and more affected by reduced
pilot alertness during operational helicopter flight compared to TS.Steinman Y, van den Oord MHAH, Frings-Dresen MHW, Sluiter JK. Flight performance aspects during military helicopter flights. Aerosp Med Hum Perform. 2019; 90(4):389–395.
New ACC/AHA Blood Pressure Guidelines and the Operational Readiness of Naval Aviators and Aircrew
Authors: Johnson Margaret C. , Banaag Amanda L. , Condie Karyn J. , Servies Tammy E. , Pérez Koehlmoos Tracey L.
Published: March 2019

INTRODUCTION: Hypertension, also known as high blood pressure, is the “silent killer” and may lead to more severe conditions if left unmanaged. Hypertension in service members of the U.S. military has the potential to negatively impact readiness. The aim of this study
was to assess the potential impact to readiness of active duty Naval aviators and aircrew under the new 2017 ACC/AHA blood pressure guidelines.METHODS: This cross-sectional study used the Military Health System Data Repository for 2015. The population included all active duty Naval
aviators and aircrew. The absolute number and proportion of those with hypertension were compared based on previous Joint National Committee 7 and 2017 ACC/AHA guidelines. Impact to readiness was calculated based on lost work days and the number of individuals with hypertension that fit the
criteria to be medically grounded according to the U.S Naval Aeromedical Reference and Waiver Guide.RESULTS: Hypertension diagnoses will increase by 2904 individuals (599%) in the 23,492 Naval aviators and aircrew included in the population. Impact to readiness will result in an
estimate of 510 lost work days.CONCLUSION: The 2017 ACC/AHA hypertension guidelines will lead to a dramatic increase in hypertension diagnoses in this population. Depending on the U.S. Navy disposition on hypertension, the impact can be minor or substantial, but the early opportunity
for care made available with the 2017 ACC/AHA guidelines may provide long-term benefits of a healthy fighting force worth the immediate impact to readiness.Johnson MC, Banaag AL, Condie KJ, Servies TE, Pérez Koehlmoos TL. New ACC/AHA blood pressure guidelines and the operational readiness of Naval aviators and aircrew. Aerosp Med Hum Perform. 2019; 90(4):409–414.
Interrelationship Between Sex, Age, Blood Volume, and Vo2max
Authors: Koons Natalie J. , Suresh Mithun R. , Schlotman Taylor E. , Convertino Victor A.
Published: March 2019

BACKGROUND: Circulating blood volume (BV) and maximal oxygen uptake (Vo2max) are physiological characteristics important for optimal human performance in aerospace and military operational environments. We tested the hypothesis that BV and Vo2max are lower
in older people independent of sex.METHODS: To accomplish this, a “data mining” effort of an historic database generated from NASA and U.S. Air Force experiments was conducted. BV, red cell volume, plasma volume, hematocrit, and Vo2max were measured in 84
healthy individuals (24 women, 60 men) across an age range of 23 to 65 yr to assess the interrelationship between sex, age, BV, and Vo2max. Subjects were classified in age groups by < 40 yr and ≥ 40 yr; these groups identified women as pre- vs. postmenopausal.RESULTS:
Consistent with our hypothesis, comparisons revealed that men had higher BV, red cell volume, hematocrit, and Vo2max than women when standardized for body mass. Against expectations, BV was not different in older compared with younger men and women. Vo2max was not different
in older compared with younger women, while Vo2max was lower in older men.CONCLUSION: We conclude that physiological mechanisms other than BV associated with aging appear to be responsible for a decline in Vo2max of our older men. Furthermore, factors other
than menopause may also influence the control of BV in the women. Our results provide evidence that aging may not compromise men or women in scenarios where BV can affect performance in aerospace and military environments.Koons NJ, Suresh MR, Schlotman TE, Convertino VA. Interrelationship
between sex, age, blood volume, and Vo2max. Aerosp Med Hum Perform. 2019; 90(4):362–368.
A review of Age Friendly Virtual Assistive Technologies and their Effect on Daily Living for Carers and Dependent Adults.
Authors: Marston Hannah R. , Samuels Julie
Published: March 2019

Many barriers exist in the lives of older adult’s, including health, transport, housing, isolation, disability and access to technology. The appropriate integration of technology within age-friendly communities continues to offer possible solutions to these barriers and challenges. Older adults and disabled people continue to be affected and marginalized due to lack of access to the digital world. Working collaboratively with planners, policy makers and developers, social and living spaces in the future will ensure that residents are equipped to live in an era that continues to be led by, and is dependent upon, access to technology. This review paper uniquely draws together the small volume of literature from the fields of gerontology, gerontechnology, human computer interaction (HCI), and disability. This paper examines the national and international age-friendly frameworks regarding older adults who are carers of dependent people with disabilities.
The Schizophrenic State Project - War, Media & Appropriation
Authors: Silberstein Guli
Published: March 2019

Since 2001, The Schizophrenic State Project extracts, processes and re-contextualises images of violence, suffering and protest from news media, in the form of a series of video works, distributed across the fields of video art and experimental film. The found footage, appropriated from mass media, both TV and the Internet, is processed via digital means, inspired by the situationist tradition of détournement, which is the “appropriation of existing media for critical comment” as defined by Guy Debord & Gil J. Wolman (1956). The video works included in The Schizophrenic State Project extend the practice of détournement by utilising new filmmaking tools, contemporary thinking and online footage accessibility, to create new forms of critical comment, connecting together media, art and theoretical thought.
Vancouver Tectonics
Authors: Lai Larissa
Published: March 2019

Prelude
Joanna McClelland Glass’ Mrs. Dexter and Her Daily and the Inter-play among Age, Gender and Class
Authors: Casado-Gual Núria
Published: March 2019

Following the so-called revolution of longevity, which was initiated after the Second World War, and as a result of recent scientific and social changes, multidisciplinary studies of old age, aging and ageism have increasingly been regarded as a necessity in our contemporary developed -and aged- societies. Consequently, and together with gender, class and ethnicity, age has become a prominent social and cultural marker which is explored by different discourses both as an ever-changing site of identity, and as a potential source of social discrimination. Cultural representations of aging have changed throughout the last decades in order to accommodate the increasingly plural realities whereby old age can be recognized and categorized, thereby contributing to the transformation of ‘age’ as a construct and identity marker. Out of the various artistic and communicative channels whereby old age is constantly re-presented, the theater stands out as an especially enlightening medium through which the constructedness of aging and ensuing stereotypical visions of old men and women can be explored. This paper will analyze the re-presentation of aging and its intersections with the politics of gender and class in Joanna McClelland Glass’ Mrs Dexter and Her Daily (2010). As a naturalistic two-hander which constructs its protagonists through realistic psychological portraits, the last play that this Canadian-American playwright has published to date presents two female characters in their mid-sixties whose old age is not only submitted to “the double standard” through which women’s aging is measured, to borrow from Susan Sontag’s words, but also conditioned by their diverse social positions and distinctive fictional biographies. Using theater semiotics and the latest theories of cultural gerontology as the two main methodological frameworks for this particular case study, this paper hopes to demonstrate that the theater continues to be an invaluable source of inquiry with regard to significant aspects of human life. At the same time, it intends to highlight the centrality of the experience of aging in its interconnection with other identity markers such as gender and class, as well as in the discourses that are derived from them.
Effects of Feeding Frequency on the Lying Behavior of Dairy Cows in a Loose Housing with Automatic Feeding and Milking System
Authors: Mattachini Gabriele , Pompe Johanna , Finzi Alberto , Tullo Emanuela , Riva Elisabetta , Provolo Giorgio
Published: March 2019

Management systems in modern dairy farms is an important issue in relation to animal comfort and welfare. The objective of this study was to determine the effect of feed delivery frequency on the behavior patterns, visits to an automatic milking system (AMS) and on milk production of lactating dairy cows. The study was conducted on a commercial dairy farm with automatic feeding and milking systems. Feeding treatments consisted of two different frequencies, high feed delivery frequency (11 deliveries per day) and low feed delivery frequency (six deliveries per day). Lying behavior of 20 dairy cows was electronically monitored. The results obtained showed that 11 deliveries per day feed delivery frequency decreases the number of long-duration lying bouts, which may indicate that a very high feeding frequency disturbs the cows during their resting periods and thus influences both animal comfort and milk production. High feeding frequency may disturb the duration of lying bouts and alter the pattern of lying behavior throughout the day, affecting mainly the lying time during the 60 min before and following the provision of fresh feed. Delivering feed at a low frequency allow cows to distribute more evenly their lying time over the course of the day and improve their utilization of an AMS.
Influence of Maternal Factors (Weight, Body Condition, Parity, and Pregnancy Rank) on Plasma Metabolites of Dairy Ewes and Their Lambs
Authors: Pesántez-Pacheco Jose Luis , Heras-Molina Ana , Torres-Rovira Laura , Sanz-Fernández María Victoria , García-Contreras Consolación , Vázquez-Gómez Marta , Feyjoo Pablo , Cáceres Elisa , Frías-Mateo Millán , Hernández Fernando , Martínez-Ros Paula , González-Martin Juan Vicente , González-Bulnes Antonio , Astiz Susana
Published: March 2019

Pregnancy and lactation are challenging states that affect maternal and lamb health. In Lacaune dairy sheep, we evaluated the impact of parity, pregnancy rank, and body condition on body weight and the condition of ewes and lambs in mid-pregnancy (75 ± 5 d), in late pregnancy (142 ± 4d), and postpartum (52 ± 5d pp). Maternal age was associated with initial decreases, followed by increases, in body weight and condition. After lambing, both mature and maiden ewes lost weight and body condition. Maternal indices of glucose, protein, and lipid metabolism were within physiological values during pregnancy, but postpartum values depended on maternal parity and pregnancy rank, with multiple-pregnant ewes showing a postpartum increase in glucose and maiden sheep a postpartum increase in plasma cholesterol concentration. Male lambs were heavier than female lambs at birth, and lambs born to mothers with higher body condition scores were heavier. Lambs born as singletons were heavier than those born in litters. Maternal age and pregnancy rank did not influence lamb metabolic indicators. Sex affected plasma concentrations of glucose, triglycerides, and cholesterol. Maternal metabolic indicators showed minimal effects on lamb phenotype. These results suggest that, when appropriately fed, dairy sheep can cover the metabolic demands of pregnancy and milk production, regardless of age and pregnancy rank.
Feeding Diets Moderate in Physically Effective Fibre Alters Eating and Feed Sorting Patterns without Improving Ruminal pH, but Impaired Liver Health in Dairy Cows
Authors: Kröger Iris , Humer Elke , Neubauer Viktoria , Reisinger Nicole , Zebeli Qendrim
Published: March 2019

The main challenge in dairy cattle feeding is to find a balance between the energy and physically effective fibre (peNDF), required to maintain rumen health. In an attempt to regulate the balance between energy intake and rumen buffering, we hypothesized that the content of peNDF in the diet modifies eating and feed sorting patterns of the cows. Sixteen lactating Simmental cows were switched from a diet high in peNDF, with which they were fed for one week, to a diet moderate in peNDF for four weeks. Data showed that during the moderate peNDF feeding the cows increased sorting for medium-sized particles and avoided both long and very fine particles. In addition, cows decreased their eating time per meal, but increased the number of meals per day, obviously attempting to decrease the amount of fermentable substrate per time unit while maintaining high levels of nutrient/energy intake. Although these changes during the moderate peNDF feeding went along with a lower diurnal variation of ruminal pH, feeding of the latter diet did not prevent ruminal pH drop and increased the level of all liver enzymes, indicating liver tissue damage. In conclusion, the altered eating, chewing, and sorting behaviour of the cows during the moderate peNDF feeding could not alleviate the deficiency in peNDF, which resulted in ruminal pH depression and impairment of liver health variables.
A Case-Series Report on The Use of a Salicylic Acid Bandage as a Non-Antibiotic Treatment for Early Detected, Non-Complicated Interdigital Phlegmon in Dairy Cows
Authors: Persson Ylva , Jansson Mörk Marie , Pringle Märit , Bergsten Christer
Published: March 2019

Interdigital phlegmon (IP) is an important cause of lameness in cattle. The aim of this study was to evaluate the treatment effect of a salicylic acid bandage in the interdigital space in dairy cows with early detected IP. Dairy cows (n = 109) with IP diagnosed and treated by the farmer were included in the study. On day 0, the rectal temperature, general condition, coronary circumference, and lameness score were recorded. The cow was immobilized in a trimming chute and the interdigital space was cleaned and inspected. For treatment, 1–2 tablespoons of 100% salicylic acid powder were applied into the interdigital space followed by bandaging of the hoof. On days 1–2 and days 3–5, the rectal temperature, the general condition, and the lameness score were recorded. On days 3–5, the cow was restrained, the bandage was taken off, and the coronary circumference was recorded again. Treatment of IP with salicylic acid gave a satisfactory treatment result. Within three–five days, treated cows responded with reduced lameness, lower body temperature, decreased coronary swelling, and an improved general condition compared to the day when the treatment started. Salicylic acid therefore proved to be an alternative in the treatment of early-detected non-complicated IP.
Electronic, Optical, Mechanical and Lattice Dynamical Properties of MgBi2O6: A First-Principles Study
Authors: Liu Lin , Wang Dianhui , Zhong Yan , Hu Chaohao
Published: March 2019

Electronic structure, optical, mechanical, and lattice dynamical properties of the tetragonal MgBi2O6 are studied using a first-principles method. The band gap of MgBi2O6 calculated from the PBE0 hybrid functional method is about 1.62 eV and agrees well with the experimental value. The calculations on elastic constants show that MgBi2O6 exhibits mechanical stability and strong elastic anisotropy. The detailed analysis of calculated optical parameters and effective masses clearly indicate that MgBi2O6 has strong optical response in the visible light region and high separation efficiency of photoinduced electrons and holes.
Acceleration of OCT Signal Processing with Lookup Table Method for Logarithmic Transformation
Authors: Li Xinyu , Liang Shanshan , Zhang Jun
Published: March 2019

Real-time Fourier domain optical coherence tomography (FDOCT) has been widely used in clinical applications. In order to accelerate the imaging processing and display of FDOCT, an alternative lookup table-based strategy for logarithmic transformation was presented. In this paper, real-time and high-quality FDOCT imaging display of biological tissues at an A-line rate of 62 kHz was demonstrated by optimizing the logarithmic calculation.
Relay Selection Schemes for FSO Communications over Turbulent Channels
Authors: Taher Menna Allah , Abaza Mohamed , Fedawy Mostafa , Aly Moustafa H.
Published: March 2019

Free Space Optics (FSO) Communication has attracted the attention of the researchers in the last decade due to its high data rate, security, and low cost. Relay-assisted techniques are used to divide the distance to shorter hops in order to mitigate the effects of turbulence, weather attenuation, pointing error, and geometric loss. Choosing an active relay per time slot has been proven to enhance the performance of the system and decrease the loading effect on the system when compared to all active relays. This paper investigates the best relay that can be selected according to the source to relay (S-R) channel coefficient, relay to destination (R-D) channel coefficient, and source to destination (S-D) channel coefficient. A comprehensive comparison is applied to the three following cases: (a) Broadcast phase from source to relay to select the best (Proactive-Relay); (b) Broadcast phase from relay to destination after broadcasting to all relays then select (Reactive-relays); and, (c) Direct link from source-to-best relay-to-destination to conclude which method is better for different scenarios, such as turbulence regime, number of relays, different pointing error effect, and severity of S-R as compared to R-D and vice versa. The selection methods regard to four aspects: (1) Number of relays (two or three relays); (2) Distance between Source-Relay and Relay-Destination (D = 400–600 m, 500–500 m, and 600–400 m); (3) The different turbulence of Log-normal channel and Gamma-Gamma channel (with a refractive index coefficient( C n 2 = 0.5 × 10−14, 2 × 10−14 and 5 × 10−14)); and finally, (4) Beam waist ω z (pointing error).
A VM-Based Detection Framework against Remote Code Execution Attacks for Closed Source Network Devices
Authors: Shin Youngjoo
Published: March 2019

Remote code execution attacks against network devices become major challenges in securing networking environments. In this paper, we propose a detection framework against remote code execution attacks for closed source network devices using virtualization technologies. Without disturbing a target device in any way, our solution deploys an emulated device as a virtual machine (VM) instance running the same firmware image as the target in a way that ingress packets are mirrored to the emulated device. By doing so, remote code execution attacks mounted by maliciously crafted packets will be captured in memory of the VM. This way, our solution enables successful detection of any kind of intrusions that leaves memory footprints.
Design of an Interactive Spatial Augmented Reality System for Stage Performance Based on UWB Positioning and Wireless Triggering Technology
Authors: Zhang YanXiang , Shen YiRun , Zhang WeiWei , Zhu ZiQiang , Ma PengFei
Published: March 2019

In this research, the authors designed an interactive spatial augmented reality system for stage performance based on the technologies of UWB positioning and Bluetooth® triggering. The position of the actor is obtained through the antenna tag carried by the actor and the signal base station placed on the stage. Special effects can be triggered through the Bluetooth® module according to the actor, and rendered at the relevant location on the screen, which has higher concealment. The system has a higher degree of freedom in practical applications, which can present an interactive spatial augmented reality effect, and therefore provide new possibilities for the application of spatial augmented reality in the stage performance.
Analytical Solution and Experimental Validation of the Electromagnetic Field in an IPT System
Authors: Zhang Kehan , Ren Xin , Liu Yuan , Hui Shuting , Song Baowei
Published: March 2019

This paper introduces the working principle of the inductive power transfer (IPT) system from the perspective of the electromagnetic field. Using Maxwell’s equations, the analytical solution for the electromagnetic field, synthesized by the primary and secondary circular coils in an IPT system, is deduced in detail to obtain the electric field in the IPT system, and the derivation process is easy to understand for researchers engaged in IPT. The final solutions are obtained by combining analytical derivation and the numerical integration method to find the induced voltage in the secondary coil. Finally, by comparison, the simulation results from the finite element software are in a good agreement with those from the analytical analysis. Moreover, an IPT system is set up to validate the analytical and simulation results, and the maximal relative error is under 6% in different working conditions, which shows that it is feasible to understand the working principle of IPT systems from the viewpoint of the electromagnetic field.
Effects of Temperature on the Relationship between Mode-I Fracture Toughness and Tensile Strength of Rock
Authors: Feng Gan , Wang Xiao-chuan , Kang Yong , Luo Shi-gang , Hu Yao-qing
Published: March 2019

Fracture toughness is used to characterize rock resistance to fracturing and it is important in theoretical research and engineering applications. Mode-I fracture toughness can be predicted on the basis of an empirical relationship between fracture toughness (KIC) and tensile strength (σt). In underground engineering, rocks are often subjected to different temperatures. Therefore, this paper explores the effect of temperature on the relationship between mode-I fracture toughness and tensile strength. The results show that the change trends in the KIC and σt values of rocks at temperatures from 20 °C to 600 °C are broadly consistent with each other. For rocks heat-treated to the same temperature, the KIC of the rock increases with an increase in σt. This positive correlation between KIC and σt is different in rocks heat-treated to different temperatures. Critical crack propagation radius (rIC) is an important factor in the relationship between KIC and σt and is related to the type of rock and the conditions under which it is tested. For the same rock, rIC is quite different after it has been exposed to different temperatures. The positive correlation between KIC and σt results from a similarity in the fracture morphology and properties of failure when rock is destroyed in fracture and tensile tests.
Adaptive Context-Aware and Structural Correlation Filter for Visual Tracking
Authors: Zhou Bin , Wang Tuo
Published: March 2019

Accurate visual tracking is a challenging issue in computer vision. Correlation filter (CF) based methods are sought in visual tracking based on their efficiency and high performance. Nonetheless, traditional CF-based trackers have insufficient context information, and easily drift in scenes of fast motion or background clutter. Moreover, CF-based trackers are sensitive to partial occlusion, which may reduce their overall performance and even lead to failure in tracking challenge. In this paper, we presented an adaptive context-aware (CA) and structural correlation filter for tracking. Firstly, we propose a novel context selecting strategy to obtain negative samples. Secondly, to gain robustness against partial occlusion, we construct a structural correlation filter by learning both the holistic and local models. Finally, we introduce an adaptive updating scheme by using a fluctuation parameter. Extensive comprehensive experiments on object tracking benchmark (OTB)-100 datasets demonstrate that our proposed tracker performs favorably against several state-of-the-art trackers.
Documenting a People yet to Be Named: History of a Bar Hostess
Authors: Mihalopoulos Bill
Published: March 2019

The paper focuses on Imamura Shōhei’s History of Post-War Japan as Told by a Bar Hostess (Nippon Sengoshi—Madamu Onboro no Seikatsu), a documentary released for general viewing in 1970. The subject of the documentary was Azaka Emiko, the uninhibited middle-aged owner of the bar Onboro in the port city of Yokosuka, home to a U.S. naval base. Emiko embodied the phantasmagoric (chimimōryō) lowlifes who inhabited the nooks and crannies of Japanese cities and went about their lives without resentment or guilt, unburdened by familial responsibility and social norms that fascinated Imamura. While other intellectuals and film makers were obsessing about the status of Japanese democracy, Imamura chose to focus on people such as Emiko to identify the psychological and moral changes undergone by the Japanese people during three decades of post-war recovery and growth.
Effects of Anthropogenic Aerosols on a Heavy Rainstorm in Beijing
Authors: Guo Chunwei , Xiao Hui , Yang Huiling , Wen Wei
Published: March 2019

A heavy rainstorm occurred in Beijing on 19–20 July 2016. The Weather Research and Forecasting Model coupled with Chemistry (WRF-Chem) was used to investigate the effects of anthropogenic aerosols on precipitation and microphysical processes. Three conditions were simulated by altering the anthropogenic emissions. When the anthropogenic emissions were increased by 10 times, the area-average accumulated rainfall amount and maximum accumulated rainfall amount both decreased. The cloud water mixing ratio increased and the rain mixing ratio decreased. The radii of cloud droplets decreased, and the collision efficiency of cloud water by rain and the autoconversion rate of cloud water into rain were both low. When the anthropogenic emission was 10% of the original emission, the area of accumulated rainfall amounts greater than 25 mm in the Beijing area was 10% larger than those of the other two tests. The collision efficiency and autoconversion rate of cloud water into rain were high for large contact areas and large cloud droplets. The graupel mixing ratio was the largest. Thus, the process of melting of graupel into rain was the largest. In the WRF-Chem model, the aerosols did not participate as ice nuclei (IN) in the ice-phase microphysical processes, and therefore the aerosols could influence only the warm rain processes and mix-phased processes near the freezing level line. For no influence on ice-phase microphysical processes, the snow and ice mixing ratios did not show many differences among the different tests.
On the Predictability of Radiation Fog Formation in a Mesoscale Model: A Case Study in Heterogeneous Terrain
Authors: Bergot Thierry , Lestringant Renaud
Published: March 2019

This study evaluates the predictability of the formation phase of a radiation fog event observed during the night of 31 October 2015 to 01 November 2015 in the north-east of France at three sites managed by OPE (Observatoire Pérenne de l’Environnement). The fog layer shows significantly different behaviors at the three areas, which are located only a few kilometers apart. Three fog life cycles were observed: the formation of a dense adiabatic fog, the formation of a thin patchy fog, or no fog formation despite favorable conditions. This event was studied with the Meso-NH numerical mesoscale model at two horizontal resolutions, 500 m and 50 m. Simulations at 50 m allow estimation of the spread of the predicted parameters over the heterogeneous terrain studied. These numerical simulations strongly suggest that this event involved numerous interactions and complex circulations. The wind above the nocturnal boundary layer greatly affects the transition of shallow patchy fog into thick adiabatic fog. These numerical simulations also show that the occurrence and type of fog could be very different over a small but heterogeneous area. It is also interesting to note that the spread of the simulated parameters was very high during the transition from shallow fog to a deep fog layer. The spread was concentrated during the regime transition between the fog formation and its maturity. This appeared to be the result of the complex interplay of processes at numerous ranges of scale. A new concept called “pseudo-process diagram” is presented. These pseudo-process diagrams are very good tools to analyze fog, and allow a good illustration of the spread of fog during this chaotic phase. This kind of concept seems a promising tool to analyze fog predictability in depth.
Inhibition of Oncogenic Kinases: An In Vitro Validated Computational Approach Identified Potential Multi-Target Anticancer Compounds
Authors: Ikram Nazia , Mirza Muhammad Usman , Vanmeert Michiel , Froeyen Matheus , Salo-Ahen Outi M. H. , Tahir Muhammad , Qazi Aamer , Ahmad Sarfraz
Published: March 2019

Tumorigenesis in humans is a multistep progression that imitates genetic changes leading to cell transformation and malignancy. Oncogenic kinases play a central role in cancer progression, rendering them putative targets for the design of anti-cancer drugs. The presented work aims to identify the potential multi-target inhibitors of oncogenic receptor tyrosine kinases (RTKs) and serine/threonine kinases (STKs). For this, chemoinformatics and structure-based virtual screening approaches were combined with an in vitro validation of lead hits on both cancerous and non-cancerous cell lines. A total of 16 different kinase structures were screened against ~739,000 prefiltered compounds using diversity selection, after which the top hits were filtered for promising pharmacokinetic properties. This led to the identification of 12 and 9 compounds against RTKs and STKs, respectively. Molecular dynamics (MD) simulations were carried out to better comprehend the stability of the predicted hit kinase-compound complexes. Two top-ranked compounds against each kinase class were tested in vitro for cytotoxicity, with compound F34 showing the most promising inhibitory activity in HeLa, HepG2, and Vero cell lines with IC50 values of 145.46 μM, 175.48 μM, and 130.52 μM, respectively. Additional docking of F34 against various RTKs was carried out to support potential multi-target inhibition. Together with reliable MD simulations, these results suggest the promising potential of identified multi-target STK and RTK scaffolds for further kinase-specific anti-cancer drug development toward combinatorial therapies.
Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
Authors: Prabhu Kirti S. , Siveen Kodappully S. , Kuttikrishnan Shilpa , Jochebeth Anh , Ali Tayyiba A. , Elareer Noor R. , Iskandarani Ahmad , Quaiyoom Khan Abdul , Merhi Maysaloun , Dermime Said , El-Elimat Tamam , Oberlies Nicholas H. , Alali Feras Q. , Steinhoff Martin , Uddin Shahab
Published: March 2019

Greensporone A is a fungal secondary metabolite that has exhibited potential in vitro for anti-proliferative activity in vitro. We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. Greensporone A-mediated inhibition of proliferation is found to be associated with the induction of apoptotic cell death. Greensporone A treatment of leukemic cells causes inactivation of constitutively activated AKT and its downstream targets, including members GSK3 and FOXO1, and causes downregulation of antiapoptotic genes such as Inhibitor of Apoptosis (IAPs) and Bcl-2. Furthermore, Bax, a proapoptotic member of the Bcl-2 family, was found to be upregulated in leukemic cell lines treated with greensporone A. Interestingly, gene silencing of AKT using AKT specific siRNA suppressed the expression of Bcl-2 with enhanced expression of Bax. Greensporone A-mediated increase in Bax/Bcl-2 ratio causes permeabilization of the mitochondrial membrane leading to the accumulation of cytochrome c in the cytoplasm. Greensporone A-induced cytochrome c accumulation causes the activation of caspase cascade and cleavage of its effector, poly(ADP-ribose) polymerase (PARP), leading to apoptosis. Greensporone A-mediated apoptosis in leukemic cells occurs through the generation of reactive oxygen species (ROS) due to depletion of glutathione (GSH) levels. Finally, greensporone A potentiated the anticancer activity of imatinib in leukemic cells. In summary, our study showed that greensporone A suppressed the growth of leukemic cells via induction of apoptotic cell death. The apoptotic cell death occurs by inhibition of AKT signaling and activation of the intrinsic apoptotic/caspase pathways. These results raise the possibility that greensporone A could be developed as a therapeutic agent for the treatment of leukemia and other hematological malignancies.
Found in Translation: The Utility of C. elegans Alpha-Synuclein Models of Parkinson’s Disease
Authors: Gaeta Anthony L. , Caldwell Kim A. , Caldwell Guy A.
Published: March 2019

Parkinson’s Disease (PD) is the second-most common neurodegenerative disease in the world, yet the fundamental and underlying causes of the disease are largely unknown, and treatments remain sparse and impotent. Several biological systems have been employed to model the disease but the nematode roundworm Caenorhabditis elegans (C. elegans) shows unique promise among these to disinter the elusive factors that may prevent, halt, and/or reverse PD phenotypes. Some of the most salient of these C. elegans models of PD are those that position the misfolding-prone protein alpha-synuclein (α-syn), a hallmark pathological component of PD, as the primary target for scientific interrogation. By transgenic expression of human α-syn in different tissues, including dopamine neurons and muscle cells, the primary cellular phenotypes of PD in humans have been recapitulated in these C. elegans models and have already uncovered multifarious genetic factors and chemical compounds that attenuate dopaminergic neurodegeneration. This review describes the paramount discoveries obtained through the application of different α-syn models of PD in C. elegans and highlights their established utility and respective promise to successfully uncover new conserved genetic modifiers, functional mechanisms, therapeutic targets and molecular leads for PD with the potential to translate to humans.
Localization of Free and Bound Metal Species through X-Ray Synchrotron Fluorescence Microscopy in the Rodent Brain and Their Relation to Behavior
Authors: Neely Caroline L. C. , Lippi Stephen L. P. , Lanzirotti Antonio , Flinn Jane M.
Published: March 2019

Biometals in the brain, such as zinc, copper, and iron, are often discussed in cases of neurological disorders; however, these metals also have important regulatory functions and mediate cell signaling and plasticity. With the use of synchrotron X-ray fluorescence, our lab localized total, both bound and free, levels of zinc, copper, and iron in a cross section of one hemisphere of a rat brain, which also showed differing metal distributions in different regions within the hippocampus, the site in the brain known to be crucial for certain types of memory. This review discusses the several roles of these metals in brain regions with an emphasis on hippocampal cell signaling, based on spatial mapping obtained from X-ray fluorescence microscopy. We also discuss the localization of these metals and emphasize different cell types and receptors in regions with metal accumulation, as well as the potential relationship between this physiology and behavior.
Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells
Authors: Gourzones Claire , Bellanger Céline , Lamure Sylvain , Gadacha Ouissem Karmous , De Paco Elvira Garcia , Vincent Laure , Cartron Guillaume , Klein Bernard , Moreaux Jérôme
Published: March 2019

Background: Multiple myeloma (MM) is the second most common hematological cancer after lymphoma. It is characterized by the accumulation of clonal malignant plasma cells within the bone marrow. The development of drug resistance remains a major problem for effective treatment of MM. Understand the mechanisms underlying drug resistance in MM is a focal point to improve MM treatment. Methods: In the current study, we analyzed further the role of redox imbalance induction in melphalan-induced toxicity both in human myeloma cell lines (HMCLs) and primary myeloma cells from patients. Results: We developed an in-vitro model of short-term resistance to high-dose melphalan and identified that pretreatment with physiological concentration of GSH protects HMCLs from melphalan-induced cell cycle arrest and cytotoxicity. We validated these results using primary MM cells from patients co-cultured with their bone marrow microenvironment. GSH did not affect the ability of melphalan to induce DNA damages in MM cells. Interestingly, melphalan induced reactive oxygen species, a significant decrease in GSH concentration, protein and lipd oxydation together with NRF2 (NF-E2-related factor 2) pathway activation. Conclusions: Our data demonstrate that antioxidant defenses confers resistance to high dose melphalan in MM cells, supporting that redox status in MM cells could be determinant for patients’ response to melphalan.