bluuebunny/crossref_metadata_2025 huggingface dataset:
Un essaimage à chaud gagnant-gagnant ? Comprendre les ancres du sentiment de réussite
Authors: Lellis Alcantara Brunna , Gabarret Inès
Published: July 2024

Traduction incomplète du terme « spin-off », le concept d’essaimage a peu été étudié en France et la littérature anglo-saxonne s’intéressant à ce concept n’est pas toujours bien adaptée au contexte français. Ici, les études ont longtemps desservi l’essaimage en le réduisant à un outil de reclassement ou une pratique douce de licenciement. L’essaimage couvre l’ensemble des situations de création et reprise d’entreprise par les salariés avec un appui de leur ex-employeur. Cela peut se faire à la demande du salarié ou à la demande de l’entreprise. L’essaimage est défini comme gagnant-gagnant quand il s’agit d’une externalisation d’activités et une possible coopération commerciale. Néanmoins, pouvons-nous parler d’un essaimage gagnant-gagnant lors des pratiques de réduction de personnel ? Cet article s’intéresse à l’émergence du sentiment de réussite chez les salariés essaimés pouvant transformer un essaimage à chaud en gagnant-gagnant.
Perceptions d’un dispositif pédagogique innovant par le prisme des étudiants : Le cas d’une approche par projet inter-Masters
Authors: Arena Lise , Ballatore Marta , Oriol Nathalie
Published: July 2024

Cet article porte sur la transformation des pratiques d’enseignement à l’Université par le prisme de la perception des étudiants, d’un dispositif d’hybridation. Un challenge inter-Masters scénarisé selon une approche par projet fait l’objet de l’étude dans le cadre d’une recherche-intervention. En explicitant quatre types de perception, l’article montre l’efficacité de cette approche à activer les leviers d’engagement des étudiants.
Territoires zéro chômeur de longue durée au prisme des communs
Authors: Le Guillou Daniel
Published: July 2024

Partant de convergences observées entre les fondements du projet « Territoires zéro chômeur de longue durée » (TZCLD) et l'approche des communs, cet article propose une analyse des enseignements de l'expérimentation et des enjeux de la pérennisation du projet en mobilisant les principes fondamentaux des communs. Au terme de cette analyse, il apparaît qu'un des enjeux majeurs réside dans un alignement fort de la gouvernance polycentrique du projet et des règles de gestion définies par les pôles de cette gouvernance avec un référentiel de valeur hétérodoxe.
Au nom de la mixité
Authors: Brun Solène
Published: July 2024

À partir d’une enquête menée entre 2015 et 2017 auprès de familles issues de l’adoption internationale et de familles fondées par des couples mixtes, cet article s’intéresse aux enjeux de la prénomination des enfants. Dans ces deux types de familles racialement mixtes où les parents doivent négocier des appartenances et origines multiples, le choix du prénom revêt des enjeux symboliques particuliers. Ceux-ci se traduisent par des logiques et des stratégies d’inscription dans les différentes lignées familiales, mais aussi de définition identitaire, sur un plan national et sur un plan racialisé. À ce titre, cet article étudie une dimension encore peu explorée de la sociologie des prénoms mais aussi de la sociologie de la race en France, en prêtant attention à la dimension racialisée des logiques sociales de la prénomination.
Les « médiums malléables » : contribution à une théorie des médiums en design
Authors: Gentès Annie
Published: July 2024

Les matériaux, en plus de leurs caractéristiques physiques, culturelles et politiques, servent de médiums dans lesquels les univers subjectifs des designers peuvent s’incarner. Cette hypothèse s’appuie sur la théorie de l’agir créatif de Winnicott, qui souligne comment notre rapport au monde est à la fois tangible et imaginaire, ce qui nous permet de reconfigurer les éléments matériels de nos environnements. Dans la continuité des travaux de Winnicott, les psychanalystes Marion Milner et Denis Roussillon ont approfondi le questionnement sur les propriétés des médiums qui peuvent soutenir cette activité créative de projection subjective. Ils avancent le concept de « médiums malléables » et proposent cinq propriétés qui, d’après eux, caractérisent ces médiums capables de soutenir une activité créative : l’indestructibilité, l’extrême sensibilité, l’indéfinie transformation, l’inconditionnelle disponibilité et enfin, l’animation propre. Leurs travaux éclairent les rapports aux matériaux dans l’activité créative et permettent de mieux comprendre la dynamique des médiums comme milieux et matrices de formation accueillant des projections du monde intérieur des designers.
« De la ferraille et de la sueur »
Authors: Dahane Aymane
Published: July 2024

Le Street Workout (SWT), mélange de musculation au poids du corps, de gymnastique informelle et d’influences hip-hop, est né de la précarité des quartiers populaires américains. Il s’est diffusé mondialement dès 2008 via YouTube, notamment dans les quartiers populaires français. Cet article socio-anthropologique, adoptant une approche ethnographique immersive, explore comment la jeunesse d’un quartier périphérique strasbourgeois a créé un spot de SWT dans un centre socioculturel. Cette activité, à la fois physique, sportive, artistique et ludique, se transforme en une forme d’éducation populaire, permettant aux jeunes d’apprendre et de transformer leurs expériences de vulnérabilité en résistance, émancipation et reconnaissance sociale face à leurs conditions de vie.
La falacia de la comunidad agraria-indígena de las dos izquierdas mexicanas: una aproximación crítica desde el megaproyecto Tren Maya
Authors: Torres-Mazuera Gabriela
Published: July 2024

Frente a un proceso de intensa desagrarización del mundo rural, la cuestión agraria en México, una de las principales arenas de discusión política y articulación social en los años de la posrevolución, ha menguado hasta casi desaparecer. No obstante, su importancia resurge cuando se trata de implementar megaproyectos de infraestructura o energía o se plantean alternativas posdesarrollistas desde movilizaciones encuadradas en reclamos de derechos colectivos. Ahí, la tenencia de tierra, generalmente de tipo ejidal o comunal, remite de nueva cuenta a la cuestión agraria. En este trabajo exploraré en qué medida y sentido, un Gobierno federal autodenominado de izquierda ha impulsado un cambio de enfoque en el ámbito agrario y, a su vez, cómo éste ha sido resistido y disputado por movilizaciones, también de izquierda, que cuestionan el modelo de desarrollo nacional materializado en megaproyectos. En específico, describiré la primera fase de implementación del “Tren Maya” que remite al acceso de la tierra/territorio, en una región indígena, a fin de develar el imaginario compartido de ambas izquierdas en torno a lo que identifico como “comunidad agraria-indígena”. Esta última, ha fungido como modelo ideal que amalgama institucionalmente al ejido y a la comunidad indígena para concebirlas como entidades equiparables y socioculturalmente homogéneas.
Cuatro años de retrocesos y resistencias: Mujeres y movimiento feminista ante el Gobierno de López Obrador
Authors: Melgar Lucía , Tinat Karine
Published: July 2024

Este artículo analiza las acciones del Gobierno de López Obrador, a partir de su elección en 2018, ante el movimiento feminista y la situación de las mujeres en México. Primero, es necesario observar los logros anteriores a la llegada de AMLO al poder, en términos de lucha contra las desigualdades entre hombres y mujeres, sin olvidar los problemas que persistían, como los relacionados con los feminicidios y su impunidad, y de los que se esperaba que un gobierno progresista intentara resolver. Segundo, se estudia cómo las políticas públicas llevadas a cabo después de 2018 han ido empeorando la situación de las mujeres en todos los niveles: social, laboral, económico, jurídico, etc. El artículo también analiza la inercia del Gobierno de López Obrador frente a los graves efectos de la pandemia de COVID-19 en las mujeres. Desde hace más de una década, las movilizaciones feministas han ganado fuerza en América Latina y algunas batallas, como la de la legalización del aborto, se están librando en algunos lugares. En México, toda la esperanza está en la capacidad de movilizarse de los colectivos y redes feministas, y de la sociedad civil, para contrarrestar los retrocesos y medidas gubernamentales erradas.
La politique minière et énergétique du gouvernement de la Quatrième transformation. Quand l’atténuation de la conflictualité permet l’intensification de l’extractivisme
Authors: Levy Simon
Published: July 2024

Si dans les dernières décennies, les gouvernements néolibéraux ont mené une politique consistant à concéder aux entreprises privées la majeure partie des activités extractives, le gouvernement de la Cuarta Transformación cherche à réaffirmer la place des entreprises paraétatiques dans leur réalisation. Afin de conserver le soutien d’une partie des organisations contestataires locales, le gouvernement mobilise le registre indigéniste et procède à la suspension de divers projets miniers et énergétiques. Cependant, loin de remettre en cause l’extraction intensive des ressources naturelles, ces dispositifs de gouvernementalité permettent la reproduction de l’extractivisme sous une nouvelle forme.
AMLO contre le cannabis : le tout-puissant veto présidentiel à la trajectoire de légalisation du cannabis au Mexique
Authors: Rivera-Vélez Luis
Published: July 2024

L’échec du processus de légalisation du cannabis au Mexique illustre comment le président AMLO devient un acteur veto tout-puissant en comparaison à ses prédécesseurs. Utilisant la théorie des acteurs veto, et fondé sur une enquête qualitative pour retracer les détails du processus décisionnel, l’article montre que le président acquiert des pouvoirs de blocage exceptionnels grâce à deux phénomènes principaux. Premièrement, AMLO arrive au pouvoir avec des majorités parlementaires absolues, ce qui lui permet d’absorber les capacités de veto des institutions parlementaires. Deuxièmement, AMLO neutralise progressivement les pouvoirs de contournement des blocages, promettant de soumettre la décision au référendum, contestant les décisions de la Cour suprême, ou instaurant une bureaucratie favorable au changement, mais contrôlée. Depuis la montée d’AMLO au pouvoir, tout espoir de changement en faveur du cannabis s’évapore au Mexique, malgré un alignement des forces politiques en faveur au niveau national et une tendance régionale à assouplir la prohibition de cette substance.
Le Mexique s’est-il polarisé ? Changement et continuités d’une géographie électorale plurielle et fragmentée
Authors: Sonnleitner Willibald
Published: July 2024

Depuis l’élection d’Andrés Manuel López Obrador (AMLO) à la présidence, en 2018, la politique mexicaine semble s’organiser autour de deux pôles antagoniques irréconciliables. Cependant, la bipolarisation de la classe politique ne se reflète pas dans le vote des électeurs, qui demeure pluriel et fragmenté. Cette étude s’intéresse aux effets de l’alternance sur la reconfiguration du système de partis dans une perspective socioterritoriale et historique, en analysant les onze élections législatives tenues depuis 1991 à l’échelle des 300 circonscriptions électorales. Le « tsunami » de 2018 fut le résultat de l’effondrement des trois partis qui avaient structuré la transition politique jusqu’en 2015. Plutôt que de reconcentrer le vote, le gouvernement d’AMLO s’appuie sur une coalition composite, face à une opposition encore plus hétérogène. Loin de se diviser autour d’un clivage bipolaire, les géographies électorales émergeantes en 2021 sont éminemment plurielles. Elles révèlent des ruptures, mais aussi des continuités avec un processus plus large de décomposition politique.
Instante:
Authors: Viana Helio Fernandes , Von Zuben Marcos de Camargo
Published: July 2024

Este artigo discute a experiência do Instante (Augenblick) à luz da ontologia da subjetividade desenvolvida por Kierkegaard, Nietzsche e Heidegger. O trabalho propõe que o Instante constitui uma experiência concreta de ruptura que tem como fundo e correlato a mediania pública niveladora. No Instante, instala-se a angústia que revela o domínio do público sobre a subjetividade (como publicidade, niilismo e domínio técnico). Ao mesmo tempo, revela-se a possibilidade de recuperação do ser si mesmo (Selbst) mais próprio na singularidade. Conversão, superação, apropriação ou fuga para a impessoalidade constituem possibilidades abertas no Instante. Nesse horizonte, o artigo oferece elementos para a compreensão da experiência que se nomeia com a noção de Instante e sua pertinência para pensar uma ética da singularidade.
Semantic Web Techniques for Extracting and Analyzing of Cropland Abandonment in Hilly Areas
Authors: Gong Yuye , Li Yun , Dong Liang , Li Lerong , Yuan Jing , Xie Linlin , Guo Yunling , Yin Ping
Published: July 2024

Due to rising rural labor costs, farmland abandonment is common in China's hilly areas. Timely, accurate extraction of its spatiotemporal changes is crucial for sustainable farmland use. This study presents a novel approach for extracting abandoned cropland using NDVI time series from Sentinel-2 satellite images, exploiting the difference in vegetation phenology between abandoned and cultivated croplands. Dynamic Time Warping (DTW) algorithm was used to determine the similarity between NDVI time-series curves of different cropland types. The similarity metrics were used to find the optimal NDVI threshold for abandoned cropland through F1-score evaluation. The method's overall accuracy is 92.4%, higher than comparison methods at 84.60% and 75.6%. The approach captures year-round vegetation changes, expands time dimension data, and improves accuracy. Spatiotemporal analysis revealed decreased patch size, increased shape complexity, and more dispersed distribution of abandoned cropland over time. Major factors were proximity to settlements, roads, water bodies.
Research on the Influence of a New Media Mobile Terminal on Learner Participation and Autonomous Learning Ability
Authors: Liu Yuling , Abu Bakar Juliana Aida , Alwi Asmidah Binti
Published: July 2024

Due to the rapid development of internet technology, the field of education is undergoing a revolutionary change. The purpose of this study is to explore how new media mobile terminals affect the learning style of college students, paying special attention to the changes in learners' participation and autonomous learning ability. Traditional learning methods have not sufficiently met the needs of contemporary college students, and the rise of new media mobile terminals has provided convenient for learning anytime and anywhere. Digitally competent college students have gradually become less dependent on traditional learning and turned to more independent learning methods. This study will analyze the specific influence of new media mobile terminals on learners' participation and autonomous learning abilities in order to provide useful insights for innovation in education and optimization of college students' learning methods.
The Impact of Corporate Social Responsibility Initiatives of Multina-tional Enterprises on Consumer Purchase Intentions and the Influence of Consumer Ethnocentrism
Authors: Boyagoda Hasitha , Weerasekera Sandun
Published: July 2024

This study examines the impact of Corporate Social Responsibility (CSR) initiatives of Mul-tinational Enterprises (MNEs) on purchase intentions of Sri Lankan consumers. An online self-administered questionnaire was sent to 183 consumers of MNE products in Sri Lanka to obtain responses, while statistical techniques in the form of correlation analysis, the Sobel test, and the moderator regression analysis were used in the data analyses.Out of the three hypotheses established, H1 and H2 were accepted while H3 was rejected. In other words, sufficient evidence was established to accept a positive relationship between CSR initiatives of MNEs and consumer purchase intentions, and also consumer awareness mediated the above relationship. However, there was insufficient evidence to accept that consumer ethno-centrism moderated the relationship between consumer awareness of CSR and consumer purchase intentions.The study helps to advance the Theory of Social Identity, which underpins the study, while also advancing the constructs of CSR, consumer awareness of CSR, consumer ethnocen-trism, and consumer purchase intentions by attempting to extend related literature that has used this theory and variables. MNEs in Sri Lanka engage in a surfeit of CSR initiatives, with rather limited knowledge of its impact. Therefore, the study has implications for man-agers of MNEs to aid in understandingthe attitudes and awareness of CSR of Sri Lankan consumers so that they can use CSR as a strategic tool in their marketing activities.
Renal IL-23–Dependent Type 3 Innate Lymphoid Cells Link Crystal-induced Intrarenal Inflammasome Activation with Kidney Fibrosis
Authors: Frasconi Teresa M , Kurts Christian , Dhana Ermanila , Kaiser Romina , Reichelt Miriam , Lukacs-Kornek Veronika , Boor Peter , Hauser Anja E , Pascual-Reguant Anna , Bedoui Sammy , Turner Jan-Eric , Becker-Gotot Janine , Ludwig-Portugall Isis
Published: July 2024

Chronic inflammasome activation in mononuclear phagocytes (MNPs) promotes fibrosis in various tissues, including the kidney. The cellular and molecular links between the inflammasome and fibrosis are unclear. To address this question, we fed mice lacking various immunological mediators an adenine-enriched diet, which causes crystal precipitation in renal tubules, crystal-induced inflammasome activation, and renal fibrosis. We found that kidney fibrosis depended on an intrarenal inflammasome-dependent type 3 immune response driven by its signature transcription factor Rorc (retinoic acid receptor-related orphan receptor C gene), which was partially carried out by type 3 innate lymphoid cells (ILC3s). The role of ILCs in the kidney is less well known than in other organs, especially that of ILC3. In this article, we describe that depletion of ILCs or genetic deficiency for Rorc attenuated kidney inflammation and fibrosis. Among the inflammasome-derived cytokines, only IL-1β expanded ILC3 and promoted fibrosis, whereas IL-18 caused differentiation of NKp46+ ILC3. Deficiency of the type 3 maintenance cytokine, IL-23, was more protective than IL-1β inhibition, which may be explained by the downregulation of the IL-1R, but not of the IL-23R, by ILC3 early in the disease, allowing persistent sensing of IL-23. Mechanistically, ILC3s colocalized with renal MNPs in vivo as shown by multiepitope-ligand cartography. Cell culture experiments indicated that renal ILC3s caused renal MNPs to increase TGF-β production that stimulated fibroblasts to produce collagen. We conclude that ILC3s link inflammasome activation with kidney inflammation and fibrosis and are regulated by IL-1β and IL-23.
A common complaint does not always mean a common diagnosis
Authors: Cavaleri Francesco , Poggiali Erika , Porta Lorenzo
Published: July 2024

An 83-year-old woman was referred to our Emergency Department (ED) for a chronic pericardial effusion with exertional dyspnoea that had been worse over the past several days. She denied any chest pain, syncope, fever, or leg swelling. She suffered from hypertension, heart failure NYHA I, diabetes mellitus type 2, and essential tremor treated with carvedilol, furosemide, olmesartan-hydrochlorothiazide, acetylsalicylic acid, and dapagliflozin. Her physical examination revealed no abnormalities. Her vital signs were blood pressure 130/70 mmHg, heart rate 70 bpm, peripheral oxygen saturation 95% in room ambient, and respiratory rate 18/min. Laboratory findings, including C-reactive protein and troponin T, were in the normal range. The electrocardiogram showed a sinus rhythm with normal atrioventricular conduction and ventricular repolarization. Point-of-care ultrasound documented an A-line pattern without pleural effusion and a diffuse and large (30 mm fluid strip) pericardial effusion without signs of cardiac tamponade and unchanged from the previous echocardiogram (Video 1). It also showed a large pulsing mass 6x6 cm close to the right atrium with a predominant systolic flow (Video 2, Video 3).
PDZD8 Augments Endoplasmic Reticulum-Mitochondria Contact and Regulates Ca2+ Dynamics and Cypd Expression to Induce Pancreatic β-Cell Death during Diabetes
Authors: Liu Yongxin , Wei Yongqing , Jin Xiaolong , Cai Hongyu , Chen Qianqian , Zhang Xiujuan
Published: July 2024

Background: Diabetes mellitus (DM) is a chronic metabolic disease that poses serious threats to human physical and mental health worldwide. The PDZ domain-containing 8 (PDZD8) protein mediates mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) formation in mammals. We explored the role of PDZD8 in DM and investigated its potential mechanism of action.Methods: High-fat diet (HFD)- and streptozotocin-induced mouse DM and palmitic acid (PA)-induced insulin 1 (INS-1) cell models were constructed. PDZD8 expression was detected using immunohistochemistry, quantitative real-time polymerase chain reaction (qRT-PCR), and Western blotting. MAM formation, interactions between voltage-dependent anion-selective channel 1 (VDAC1) and inositol 1,4,5-triphosphate receptor type 1 (IP3R1), pancreatic β-cell apoptosis and proliferation were detected using transmission electron microscopy (TEM), proximity ligation assay (PLA), terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay, immunofluorescence staining, and Western blotting. The mitochondrial membrane potential, cell apoptosis, cytotoxicity, and subcellular Ca2+ localization in INS-1 cells were detected using a JC-1 probe, flow cytometry, and an lactate dehydrogenase kit.Results: PDZD8 expression was up-regulated in the islets of HFD mice and PA-treated pancreatic β-cells. PDZD8 knockdown markedly shortened MAM perimeter, suppressed the expression of MAM-related proteins IP3R1, glucose-regulated protein 75 (GRP75), and VDAC1, inhibited the interaction between VDAC1 and IP3R1, alleviated mitochondrial dysfunction and ER stress, reduced the expression of ER stress-related proteins, and decreased apoptosis while increased proliferation of pancreatic β-cells. Additionally, PDZD8 knockdown alleviated Ca2+ flow into the mitochondria and decreased cyclophilin D (Cypd) expression. Cypd overexpression alleviated the promoting effect of PDZD8 knockdown on the apoptosis of β-cells.Conclusion: PDZD8 knockdown inhibited pancreatic β-cell death in DM by alleviated ER-mitochondria contact and the flow of Ca2+ into the mitochondria.
Korean National Burden of Disease: The Importance of Diabetes Management
Authors: Kim Chung-Nyun , Jung Yoon-Sun , Kim Young-Eun , Ock Minsu , Yoon Seok-Jun
Published: July 2024

Diagnosing the current health status and disease burden in a population is crucial for public health interventions. The ability to compare the burden of different diseases through a single measure, such as disability-adjusted life years has become feasible and continues to be produced and updated through the Global Burden of Diseases (GBD) study. However, the disease burden values of the GBD study do not accurately reflect the unique situation in a specific country with various circumstances. In response, the Korean National Burden of Disease (KNBD) study was conducted to estimate the disease burden in Koreans by considering Korea’s cultural context and utilizing the available data sources at the national level. Both studies identified non-communicable diseases, such as diabetes mellitus (DM), as the primary cause of disease burden among Koreans. However, the extent of public health interventions currently being conducted by the central and local governments does not align with the severity of the disease burden. This review suggests that despite the high burden of DM in South Korea, the current policies may not fully address its impact, underscoring the need for expanded chronic disease management programs and a shift towards prevention-focused healthcare paradigms.
Comparison the Effect of Rehabilitation at Home and Outpatient Physiotherapy after Total Knee Arthroplasty Surgery on Quality of Life and Knee Function: A Clinical Trial Study
Authors: Haghpanah Babak , Tavakoli Fatemeh , Mollaabbasi Mohammadhadi , Azadchehr Mohammad J. , Afsharirad Ali , Sadeghian Amirhossein , Taravati Amirmohammad , Shahrokh Seyedeh Ghazal , Dastgerdi Abdollah Shakiba
Published: July 2024

Background:

Primary total knee arthroplasty (TKA) is an effective procedure to better function and relief the pain in advanced osteoarthritis patients. This study aimed to evaluate the effectiveness and safety of outpatient clinic-based setting of physiotherapy versus home-based rehabilitation (HBR) for functional recovery immediately after primary TKA procedure.

Materials and Methods:

This randomized clinical trial study was conducted on patients underwent TKA in 2021–2022. Participants were randomly allocated to either “usual care” or a “home-based rehabilitation” in a 1:1 ratio. The primary outcome measurement of this study was the Knee Society Score (KSS). The secondary outcome was patient quality of life using the 36-item Short Form Survey Instrument (SF-36). Data were entered into the SPSS software 25 and analyzed.

Results:

In this study, 80 patients who underwent TKA in equal proportion in two outpatient physiotherapy (36 women; average age 64.37 ± 5.12 years) and home rehabilitation (33 women; average age 62.4 ± 4.87 years) groups were examined. The findings our study showed that after the intervention (3 and 5 months after the operation), there was no significant difference between the two groups in terms of the quality of life (total score) (P > 0.05). KSS had no significant difference between the two groups (P > 0.05).

Conclusion:

This randomized controlled trial found no significant differences in the outcomes of rehabilitation using either a HBR or a traditional outpatient physiotherapy model.
Cost-Utility Analysis of Rosuvastatin (20 mg) to Prevent Cardiovascular Diseases in Iran
Authors: Rezapour Aziz , Jafari Abdosaleh , Talebianpour Hamid
Published: July 2024

Background:

Cardiovascular diseases are a main cause of disease burden in developing and developed countries. This study aimed to evaluate the cost-utility of rosuvastatin 20 mg in contrast with no intervention for the prevention of cardiovascular disease in Iran.

Materials and Methods:

The costs and utility of rosuvastatin 20 mg were compared to nonintervention in patients with cardiovascular disease for the whole lifetime horizon in this study using the Markov model. Cost and utility data were taken from literature. After estimating the incremental cost-effectiveness ratio, a sensitivity analysis was performed using TreeAge Pro 2011 software to cope with uncertainty.

Results:

Based on finding, the expected cost and quality-adjusted life years (QALYs) of using rosuvastatin 20 mg were $300 and 12, and the values for no intervention were $56 and $10, respectively. Given the threshold of $20800, using rosuvastatin 20 mg was cost-effective compared to no intervention and the incremental cost was $122 per QALY. The results showed that the highest costs were related to admission to the coronary care unit (CCU) ward. Moreover, among the costs of paraclinical services, the highest were those of echocardiography. Furthermore, Troponin accounted for most of the cost of laboratory tests.

Conclusion:

It is recommended that policymakers consider using rosuvastatin 20 mg by cardiologists while designing clinical guidelines for the diagnosis of patients with cardiovascular diseases. Because of the high cost of cardiovascular diseases in Iran, it is suggested that policymakers should consider cost control strategies to impose lower costs on patients.
The Regulatory Variant -108C/T in the Promoter of Paraoxonase 1 (PON1) Gene has a More Important Role in Regulating PON1 Activity Compared to rs3735590 in 3ʹ-UTR in Patients with Coronary Artery Disease
Authors: Zargari Mehryar , Maadi Negar , Rezapour Maysam , Bagheri Abouzar , Fallahpour Samane , Nosrati Mani , Mahrooz Abdolkarim
Published: July 2024

Background:

This study aimed to assess the serum activity of paraoxonase 1 (PON1) in patients with coronary artery disease (CAD) based on two genetic variants including the -108C/T variant in the promoter region and the rs3735590 variant in the binding site of miR-616 at the 3ʹ-UTR of the PON1 gene.

Materials and Methods:

A total of 140 subjects who exhibited clinical symptoms of CAD underwent diagnostic coronary angiography. The patients with CAD were further categorized into two groups: single-vessel disease (SVD) and multi-vessel disease (MVD). The study variants were genotyped using the restriction fragment length polymorphism (RFLP) technique after polymerase chain reaction amplification.

Results:

After adjusting for age, gender, body mass index, metformin, and statin usage, a significant association was observed between the -108C/T variant and PON1 activity (P < 0.001). In the sub-groups of both SVD and MVD, individuals with the TC+CC genotypes exhibited significantly higher PON1 activity compared to TT homozygotes (P = 0.001 for SVD and P = 0.01 for MVD). As for the rs3735590 variant, individuals with the A allele (GA+AA genotypes) had higher PON1 activity compared to those with the GG genotype in both the SVD and MVD groups, although the results did not reach statistical significance.

Conclusions:

Our study findings indicate a significant decrease in PON1 activity among patients with obstructive CAD. Notably, our results suggest that the -108C/T variant exerts a greater influence on PON1 activity compared to the rs3735590 variant. These findings highlight the crucial role of the -108C/T variant in modulating PON1 activity within the context of atherosclerosis.
Ocular dominance and its association with retinal thickness profile – A cross-sectional study
Authors: Khan Farnaz Ahamed , Kasturi Nirupama , Deb Amit Kumar
Published: July 2024

Purpose:

The retinal thickness profile is essential for detecting ocular diseases like glaucoma and other optic neuropathies. The retinal nerve fiber layer (RNFL) thickness is affected by age, ethnicity, axial length, optic disc area, and inter-eye differences. Ocular dominance has a strong functional correlation with cerebral cortical activity. However, its relationship with RNFL thickness profile is yet to be fully established.

Methods:

A cross-sectional study was conducted in 136 healthy adults to study the association between ocular dominance and RNFL parameters measured by Spectral domain optical coherence tomography (SD-OCT) and to study the association of ocular dominance with other parameters such as handedness, intraocular pressure, average axial length, average keratometry, and refractive error. Sighting ocular dominance was detected using the Miles test, and sensory ocular dominance was detected using the fogging test. Visual acuity and refraction assessment were done, and the patients underwent ocular biometry using the Lenstar 900 machine to measure the axial length and keratometry. The RNFL thickness was measured using the Cirrus HD optical coherence tomographer.

Results:

One hundred and thirty-two (97.06%) individuals were right-handed, four (2.94%) were left-handed, 108 (79.41%) participants were right eye dominant, and 28 (20.59%) were left eye dominant. There was 100% agreement between sighting and sensory ocular dominance. The average RNFL thickness and other measured ocular parameters were comparable in the dominant and nondominant eyes. Regardless of dominance, the left eyes in the study cohort had a greater statistically significant difference in superior RNFL thickness (P < 0.05), which correlated with increased central macular thickness.

Conclusion:

Ocular dominance occurred mostly in the right eye. The RNFL thickness profile is not associated with ocular dominance in emmetropic and mild myopic individuals with normal best corrected visual acuity.
Brolucizumab-associated intraocular inflammation in Indian patients by VRSI study group
Authors: Agarwal Manisha , Muralidhar Alankrita , Shanmugam Mahesh P , Kothari Abhishek , Dudani Ajay , Maiti Aniruddha , Arora Anshu , Jayadev Chaitra , Gupta Charu , Shroff Darius , Chakraborty Debdulal , Pillai Gopal S , Lahiri Kairobi , Verma Lalit , Gopalakrishnan Mahesh , Narayanan Raja , Mishra Sanjay K , Patil Sanket , Choudhary Shailender , Chakraborty Somnath , Natesh Sribhargava , Koundanya Vikram , Aggarwal Vinod
Published: July 2024

Context:

Concerns about brolucizumab’s (Pagenax®) association with intraocular inflammation (IOI) limit its use despite its cost-effectiveness and efficacy. This multicentric study analyzes IOI incidence across 21 tertiary eyecare centers in India since its introduction in October 2020.

Purpose:

To determine the real-world incidence rate of IOI in Indian patients secondary to intravitreal brolucizumab across 21 tertiary eye care centers in India.

Settings and Design:

Retrospective multicentric, survey-based study.

Methods:

Data including number of patients treated, clinical indications, side effects encountered, and IOI case details was collected via Google Forms in 21 Indian tertiary eye care centers since October 2020. Mean, median, frequency, and standard deviation were calculated for statistical analysis.

Results:

All centers used pro re nata protocol for brolucizumab injections with a minimum injection interval of 8 weeks. The incidence of IOI was 0.79% (21 events out of 2655 eyes). Treatment indications included idiopathic polypoidal choroidal vasculopathy, neovascular age-related macular degeneration, diabetic macular edema, and off-label uses. IOI was experienced after the first injection (57%) in majority of cases with a median onset of 14 days (range: 1–65 days). IOI was mild in 28.5%, moderate in 33%, and severe in 38% of cases. Eighteen out of 21 IOI eyes recovered preinjection best corrected visual acuity or better.

Conclusions:

Our study found a lower IOI incidence (0.79%) with brolucizumab (Pagenax) in Indian patients compared to previously reported literature. IOI events were mostly mild to moderate, and post-treatment, most patients improved or maintained BCVA. Larger prospective multicentric studies with PRN dosing protocol are needed to confirm these findings.
The interdisciplinary nature of psychology and accounting: A review and research
Authors: Tran Lam Khanh , Tang Hung Tri , Nguyen Thien Huu
Published: July 2024

This article explores the symbiotic relationship between psychology and accounting, two social sciences investigating human behavior and decision-making. While they share common interests, methods, and challenges, the interdisciplinary nature of these fields requires careful consideration. Hence, this paper offers a comprehensive literature review, illuminating the interdisciplinary aspects of psychology and accounting and presenting a research agenda for future studies. The study adopts a qualitative approach comprising two primary phases. Firstly, a systematic literature review and content analysis are conducted to introduce the concept and dimensions of interdisciplinarity, along with its benefits and challenges. Subsequently, an in-depth analysis of the primary areas of interaction and collaboration between psychology and accounting is performed. The findings unveil current trends and challenges for psychology and accounting as social sciences, identify gaps and opportunities, and highlight the impact and implications of interdisciplinary collaboration and integration in psychology and accounting research. Furthermore, a suggested model is proposed to foster interdisciplinary.
Evaluation of Oral and Dental Health in Pediatric Patients with Special Health Care Needs
Authors: Yildiz Semsettin , Tekin Bahar
Published: July 2024

Purpose: The aim of this study was to compare oral hygiene, trauma incidence, DMFT and dmft index, PUFA, pufa and PUFA/pufa index of children with special educational needs according to disability status.
Materials and Methods: This cross-sectional study was conducted in special education institutions in Elazig. Age, gender, disability, presence of dental caries, dental trauma, dental abrasions, oral hygiene and cooperation status of the children were recorded. DMFT/dmft and PUFA/pufa index were used for dental caries scoring. One-way ANOVA and Chi-square tests were used to analyze the data and the significance level was determined as 0.05.
Results: There was a statistically significant difference (p
Effect of the COVID-19 Pandemic on Anxiety Level, Patient Approach and Oropharyngeal Examination in Family Medicine Outpatient Clinics: A Nationwide Study in Turkey
Authors: Alpman Nazife , Sarıca Çevik Hüsna , Solak Yavuzalp
Published: July 2024

Aim: Although there are numerous publications on the effects of COVID-19 on mental health, there is limited data on how these effects affect physicians' approach to patients.This study aimed to evaluate family physicians'(FPs) approach to the physical examination of patients who applied to family medicine(FM) outpatient clinics with upper respiratory tract infection symptoms, the influencing factors, and the relationship with FPs’ anxiety levels.
Materials and Methods: An online questionnaire form containing sociodemographic information, probable case scenarios evaluating the physicians' approach to patients with upper respiratory tract infection symptoms at different ages, and the Coronavirus Anxiety Scale(CAS) sent to FPs between 19.03.2022-25.04.2022.
Results: A total of 376 FPs were included in the study. FPs reported performing oropharynx and respiratory system examinations on 99% of patients presenting with upper respiratory tract infection symptoms before the pandemic. However, with the pandemic, an increase in avoidance behaviours, such as directing the patient to the COVID-19 test centre before examination, has been reported, and oropharynx and lung examinations are performed at lower rates. According to the CAS, 5.1% of the FPs had a level of dysfunctional anxiety that could require treatment. Oropharyngeal inspection, tongue depressor use, and lung auscultation were significantly lower in the dysfunctional anxiety group.
Conclusions: Although the CAS scores of FPs were low, it was determined that the rate of oropharyngeal examination decreased, with a higher rate in physicians with dysfunctional anxiety. To prevent the behaviour of avoiding physical examination from continuing after the pandemic, the biopsychosocial well-being of physicians should be supported, and their needs should be determined.
Osteoporotic Vertebral Fractures
Authors: Ertem Uğur
Published: July 2024

In this article, I would like to contribute to the article 'Retrospective Analysis of Osteoporotic Vertebral Fractures' from the perspective of a physiatrist. First of all, I would like to express my gratitude to Akar for this valuable article. In this study, Akar emphasized that osteoporosis and osteoporotic vertebral fractures are becoming a larger public health problem as life expectancy increases, and that early diagnosis and treatment of osteoporosis is important for prevention. As it is known, osteoporosis is an important public health problem. Osteoporotic vertebral fractures are the most common type of fracture in patients with osteoporosis, with approximately 750,000 new cases occurring each year. Only one-third of patients with osteoporotic vertebrate fractures experience acute pain. Therefore, it may not be easy to recognize in the early period. In addition, osteoporotic vertrebal fractures may be a sign of new fractures, both vertebral and non-vertebral. From this perspective, osteoporotic vertebral fractures are of great importance for patient and public health.
The frequency of triphalangeal and biphalangeal toes in the Turkish population: A radiographic study
Authors: Çataltepe Aziz , Akan Melih
Published: July 2024

Purpose: The fifth toe usually has two interphalangeal joints with three bones; nevertheless, most authors indicated that the two-boned fifth toe occurs frequently. This trial aimed to investigate the frequency of this anatomical variant in the Turkish population.
Material and Methods: The current study analyzed 1096 cases (1286 feet) with unilateral or bilateral radiographs between September 2020 and August 2022. Eighty-two cases were excluded, and 1014 cases were evaluated in this trial. Foot radiographs were assessed for biphalangealism of the second to the fifth toe. Data regarding sex, age, side, the number of phalanges of the fifth, fourth, third, and second toe, and the reason for performing radiographs were assessed.
Results: The average frequency of the biphalangeal fifth toe was 35.7%, in the fourth toe was 1.7%, in the third toe was 0.5%, and in the second toe was 0.2%. The difference in the frequency of biphalangeal and triphalangeal toes regarding sex and the right/left foot was statistically insignificant (p=0.245, p=0.815 respectively). The asymmetrical distribution of the fifth biphalangeal toe was seen in 6.9%, and the asymmetrical distribution of the fourth biphalangeal toe was 0.5% in the 189 bilateral feet radiographs.
Conclusions: The frequency of the biphalangeal fifth toe was 35.7% in the current study, which showed that this anatomical variant in the Turkish population has been similar to the other Turkish studies. The two-phalanged fifth toe must be kept in mind during the assessment of a case with foot pathologies and foot radiographs. Furthermore, the biphalangeal second, third, and fourth toes occur when the fifth toe of the same foot is biphalangeal.

Keywords: Foot anatomy, two-phalanged toes, pedal biphalangism, toe symphalangism, Turkish population.
Game Online dan Kesehatan Mental Generasi Z: Studi Kasus pada Remaja Pria di SMK MAN 5 Tasikmalaya
Authors: Azahra Astrid Sulistya , Kalfin Kalfin , Hidayana Rizki Apriva
Published: July 2024

This research investigates the impact of online games on the mental health of Generation Z, with a focus on male adolescents at SMK MAN 5 Tasikmalaya. Quantitative research methods were used to collect data through questionnaires regarding the duration of playing online games and observations of mental health. The results of data analysis show that there is a significant relationship between the duration of playing online games and mental health in male adolescents. It was found that online gaming addiction can result in decreased mental health, including social isolation, decreased academic performance, and emotional disorders. Therefore, efforts need to be made to manage the use of online games wisely to minimize the negative impact on Generation Z's mental health.
Application of Fish Waste Processing for Sustainable Livestock Feed Production A Community Engagement Study in Garut Regency
Authors: Lianingsih Nestia , Suhaimi Nurnisaa Binti Abdullah , Prabowo Agung
Published: July 2024

This community engagement study aimed to develop an application for processing fish waste into animal feed based in an incubator system in Garut Regency. The program was conducted from May to November 2023 with the primary objective of transferring technology in waste processing and animal feed production to partner groups. Methods included socialization, technical and non-technical training, and direct mentoring in animal feed pellet production. Results showed a significant improvement in the knowledge and skills of the groups in producing fish waste pellets, reducing feed production costs, and enhancing the sustainability of local livestock businesses. Challenges encountered included initial production limitations and consumer trust in new products. With in-depth scientific approaches and sustained support, the program successfully created positive impacts on the environment and community economic welfare.
International Migration Control Strategy Through Soft Power
Authors: Kamil Farhan , Rofii Muhammad Syaroni , Tairas David Ronald
Published: July 2024

It is human instinct to move from one place to another. This migration phenomenon will be followed by a movement of various aspects of life such as ideology, politics, economy, society, culture, security, demography, human resources, the environment, and various other aspects of life. Along with the times, international migration carried out by people is increasing; this is directly proportional to the advancement of technological civilization that produces innovations in the fields of information, transportation, and communication. This paper uses a qualitative approach. This research will produce descriptive data in the form of paragraphs explaining the events studied. The result of this study is that in order to influence the policy of granting visas to other countries, the country must take a persuasive approach, namely by having a high level of soft power so that it is in a bargaining position. Soft power and visa granting policies are both continuous and directly proportional. This can be proven by the top position of passport strength of a country also occupying the top position on the soft power index.
The Effect of Hygiene and Sanitation Levels on the Health Level of Prisoners
Authors: Hanafi Aziz Imam
Published: July 2024

Prisoner health is a crucial aspect of the correctional system. Unhygienic environmental conditions and poor sanitation can have fatal consequences for prisoners' health, particularly in terms of the spread of infectious diseases. This research aims to analyze the impact of hygiene levels on prisoners' health. This study employs quantitative research methods, collecting data through surveys using questionnaires and literature reviews. The collected data were analyzed using regression tests with the SPSS program. The results indicate a significant relationship between the level of hygiene and sanitation and the health status of prisoners. Prisoners living in more hygienic environments with better sanitation have better health levels. This study emphasizes the importance of improving hygiene and sanitation conditions in prisons to enhance prisoners' health.
Terapia infiltrativa do neuroma de morton: uma revisão da literatura
Authors: Caldas Cibele Rodrigues , Coutinho Ana Claudia do Nascimento , Martins Jessica Fernanda Ferreira , Tauchert Lianara Ketlin , Borges Rafaela Limongi
Published: July 2024

Introdução: ​​O neuroma de Morton (NM), descrito por Thomas George Morton é um epônimo que designa uma fibrose de nervos plantares. Sua apresentação, inicialmente cursa com dor na planta dos pés, é consideravelmente inespecífica e pode incluir parestesia referida, com possibilidade de progressão para limitação das atividades habituais. Objetivo: Buscar, na literatura,  presentes avanços no que tange a infiltração ultrassonográfica na terapêutica do neuroma de Morton. Materiais/sujeitos e métodos: Para a elaboração deste artigo de revisão foram consultados artigos científicos das bases de dados do National Center for Biotechnology Information do U.S. National Library of Medicine (PUBMED), como também a Scientific Electronic Library Online (SciELO) e a Cochrane Library. Resultados e discussão: Sabe-se que a essência do tratamento está no ajuste das pressões na região anterior do antepé. Para isso, as opções variam desde medidas conservadoras, conservadoras e invasivas. As medidas conservadoras abordam desde a correção do calçado, fisioterapia e palmilhas com apoio retrocapital diminuindo assim a carga nas cabeças metatarsais e o uso de fármacos como anti-inflamatórios não esteroides (AINEs). Em contrapartida as medidas conservadoras invasivas abrangem a utilização de infiltrações locais com corticosteroides, anestésicos locais ou até mesmo terapias mais recentes, com injeções de plasma rico em plaquetas (PRP) ou ácido hialurônico do espaço comprometido para produzir alívio que pode durar semanas a meses. E por fim, as medidas invasivas utilizadas são a opção quando ocorre falha após 9 a 12 meses no tratamento conservador, a qual menciona o tratamento cirúrgico através da neurólise e/ou neurectomia com regressão total dos sintomas. Considerações finais: A terapia infiltrativa possui uma boa eficácia, quando se trata do alívio de sintomas a curto prazo. Além disso, um parâmetro avaliado foi a influência na quantidade de infiltrações na duração da remissão dos sintomas, sendo que uma única injeção apresenta alto índice de recidivas a longo prazo. Por fim, o uso repetido desta terapia, apesar de parecer ter melhores resultados, pode levar a complicações, como atrofia da gordura plantar e mudança na pigmentação da pele.