bluuebunny/crossref_metadata_2025 huggingface dataset:
ASPECTS OF THE STRATEGIC DEVELOPMENT OF THE REGION'S ECONOMY
Authors: Evseev Artem S. , Morozova Natalia V. , Vasilieva Inessa A.
Published: December 2022

The article provides a theoretical analysis of strategic factors in the regional economic development. This analysis will help to give a clearer insight into the way a region develops economically in the process of updating its strategic factors. The relevance of the research topic is due to the fact that there is a lack of structured scientific information in covering the features in the formation of strategic factors in the development of the region's economy. Objectification and a relevant analysis of problems will help to give a clearer insight into the way the economy will develop in the regions of the country in the nearest future, taking into account various factors that have a significant impact on it. The purpose of the article is to compile a generalized representation reflecting current strategic state of the region's economic development. in order to conduct the most complete analysis of strategic factors related to the development of network and reproduction processes in the economy of the country's regions, expert and relevant methods were used when writing the article. The theoretical value of the materials presented in this article is that they deepen the knowledge of the laws underlying the strategic development of the economy in the regions. in practice, they can be used in developing federal and regional strategic programs, for adopting certain measures to develop branches of industry. Based on the analysis, it is concluded that the strategic development of the regional economy in recent years has become more intensive than earlier, but economic actors as initiators of introducing integral reproduction processes react slowly to innovations and are rarely able to create them themselves.
Thrombocytopenia and its Related Factors: A Hospital-based, Cross-sectional Study
Authors: Lai Shih-Wei , Huang Ching-Yi , Lai Hsueh-Chou , Liao Kuan-Fu , Lai Yen-Miao , Liu Chiu-Shong , Lin Tsann
Published: December 2022

Introduction: The objective of this study was to explore the association between thrombocytopenia and its related factors. Materials and Methods: This was a hospital-based, cross-sectional study. We retrospectively analysed the medical records of all patients who received periodic health examinations at a medical centre located at Taichung in Taiwan between 2000 and 2004. In all, 5585 subjects were included for further analysis. A complete physical examination, laboratory survey and abdominal ultrasonography were performed on each subject. The t-test, chi-square test and multivariate logistic regression analysis were used. Results: The subjects consisted of 3123 men (55.9%) and 2462 women (44.1%). The mean age was 49.4 ± 12.3 years (range, 20 to 87). The overall prevalence of thrombocytopenia was found to be 0.5%, higher in men than in women (0.6% vs 0.4%, P = 0.504). After controlling for the other covariates, multivariate logistic regression analysis exhibited that the factors significantly related to thrombocytopenia were increasing age (OR, 1.04; 95% CI, 1.004-1.08), anti-HCV positive (OR, 5.24; 95% CI, 2.08-13.20), liver cirrhosis (OR, 7.93; 95% CI, 2.28-27.62), and splenomegaly (OR, 18.86; 95% CI, 6.86-51.87). Conclusion: It is advisable to further check the hepatic status, if thrombocytopenia is noted.

Key words: Hepatitis C, Liver cirrhosis, Splenomegaly, Thrombocytopenia
Subcutaneous Infection with Non-mouse Adapted Dengue Virus D2Y98P Strain Induces Systemic Vascular Leakage in AG129 Mice
Authors: Tan Grace KX , Ng Jowin KW , Lim Angeline HY , Yeo Kim Pin , Angeli Veronique , Alonso Sylvie
Published: December 2022

Introduction: Dengue (DEN) is a mosquito-borne viral disease which has become an increasing economic and health burden for the tropical and subtropical world. Plasma leakage is the most life threatening condition of DEN and may lead to hypovolaemic shock if not properly managed. Materials and Methods: We recently reported a unique dengue virus strain (D2Y98P) which upon intraperitoneal (IP) administration to immunocompromised mice led to systemic viral dissemination, intestine damage, liver dysfunction, and increased vascular permeability, hallmarks of severe DEN in patients (Tan et al, PLoS Negl Trop Dis 2010;4:e672). Results: Here we report the clinical manifestations and features observed in mice subcutaneously (SC) infected with D2Y98P, which is a route of administration closer to natural infection. Similar to the IP route, increased vascular permeability, intestine damage, liver dysfunction, transient lymphopenia (but no thrombocytopenia) were observed in the SC infected mice. Furthermore, the SC route of infection was found more potent than the IP route whereby higher viral titers and earlier time-of-death rates were measured. In addition, various staining approaches revealed structurally intact blood vessels in the moribund animals despite pronounced systemic vascular leakage, as reported in dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) patients. Interestingly, measurement of soluble mediators involved in vascular permeability indicated that vascular leakage may occur at an early stage of the disease, as proposed in DEN patients. Conclusion: We believe that this novel mouse model of DEN-associated vascular leakage will contribute to a better understanding of DEN pathogenesis and represents a relevant platform for testing novel therapeutic treatments and interventions.

Key words: Dengue shock syndrome, Dengue hemorrhagic fever, Capillary leakage
Acute Pyelonephritis and Renal Abscesses in Adults—Correlating Clinical Parameters with Radiological (Computer Tomography) Severity
Authors: Lim Sey Kiat , Ng Foo Cheong
Published: December 2022

Introduction: The aim of this study is to evaluate the correlations between clinical and biochemical parameters with radiological severity of CT diagnosed acute pyelonephritis (APN) and renal abscesses, thereafter defining clinical predictors to identify patients with severe APN or renal abscesses. Materials and Methods: The inpatient medical records of all patients diagnosed with APN or renal abscesses admitted over one year were reviewed. Patients with CT imaging performed were classified into 3 groups—mild APN, severe APN and renal abscesses. Clinical and biochemical parameters were correlated with radiological severity. Results: One hundred and thirty patients were included in the study. Male gender, older age, presence of diabetes mellitus and unobstructing renal stones were significantly associated with severe APN or renal abscesses. Clinical and biochemical parameters that were associated with more severe disease include a higher leucocyte count and C-reactive proteins, left neutrophil shift, thrombocytosis or thrombocytopenia, low serum albumin, acute renal impairment and bacteremia. The percentage of patients had positive urine and blood cultures were 40.8% and 30.7% respectively. Of these patients, 97.9% had severe APN or renal abscesses on CT imaging had diabetes mellitus (DM), hypotension, acute renal failure or leucocyte count of >20K. Conclusion: Our study showed a good correlation between clinical and radiological severity in adult patients with APN and renal abscesses. Patients with severe APN or renal abscesses were likely to be diabetics presenting with hypotension, acute renal impairment and a leucocyte count of greater than 20K.

Key words: Computer topography (CT), Pyelonephritis, Renal abscess, Severity
Metaverse: A New Digital Marketing Trend
Authors:   Assistant Professor, Shri Ram College of Commerce, University of Delhi, Singh Haridarshan
Published: December 2022

Modern society is seeing a fast uptick in technology adaptation and incorporation. The development of the internet and other modern devices has made it possible for systems to become further adaptable, diverse, and sophisticated, enabling them to handle the bulk of humanity's duties and burdens. The most successful technological advances in internet adaptation are virtual worlds and augmented reality. But the increased search for technical breakthroughs has made room for the most recent virtual world, called Metaverse. Metaverse has created the presence of the digital space and changed it into the actual world so that we are no longer just dependent on the internet via our screens. Utilizing virtual or augmented reality systems, it enables users to actively involve themselves in the virtual space where they may engage and innovate everyday choices in a time-based setting. The Metaverse has improved its accessories throughout the years. In order to provide customers with a holistic and true experience with the item or commodity they desire to purchase, companies and businesses are making use of automation's special and distinguishing features. Due to the rising competitiveness in the marketing industry, the Metaverse has given businesses and traders the opportunity to investigate technology aspects for more creativity. An introduction to the metaverse and its developments is presented in this paper.
Ortaöğretim 11. Sınıf Biyoloji Ders Kitaplarındaki Dolaşım Sistemine Ait Görsellerin Bilimsel İçerik Bağlamında İncelenmesi
Authors: SEVİNÇ Ömer Seyfettin , ZEYNOĞLU Ezgi , İMERT Merve Nur
Published: December 2022

Bu çalışmada, 2020-2021 öğretim yılında okutulan, MEB Ortaöğretim 11. Sınıf Biyoloji Ders Kitaplarında yer alan “Dolaşım Sistemi” bölümüne ait görsellerden olan resimlerin bilimsel içerik açısından incelenmesi amaçlanmıştır. Ders kitaplarının her öğesinde olduğu gibi, görsel öğelerinin de metindeki bilimsel içerikle uyumlu, örtüşür durumda olması, sınıf seviyesine uygunluğu ve yanlış öğrenmelere yol açmaması son derece önemlidir. Verilerin analizinde doküman incelemesi yöntemi kullanılmış ve resimlere ait görsellerin uygunluklarının incelenmesinde ulusal ve uluslararası referans kitaplarından yararlanılmıştır. Bir görselin neden tartışmalı veya hatalı olduğu, bu görsellerdeki ilgili ifadeler, terimler incelenerek doğru şekliyle birlikte sunulmuştur. İnceleme sonucunda görselleri içeren tablolar, tespit edilen görsel hatalar ve hatalarla ilgili açıklamalar, eserlerdeki sayfa numaralarıyla birlikte değerlendirmeleriyle birlikte verilmiştir. Araştırma bulgularına göre MEB Ortaöğretim 11. Sınıf Biyoloji Ders Kitaplarındaki “İnsan Fizyolojisi” ünitesinde yer alan “Dolaşım Sistemi” bölümüne ait görsellerin bilimsel içeriklerinin taşıması gereken niteliklere tam olarak uygun bir şekilde oluşturulamadığı tespit edilmiştir. Elde edilen bulgulara göre, ders kitaplarında yer verilen görsellerdeki eksik, hatalı gösterimlerin öğrencilerde yanlış öğrenme ve kavram yanılgısına neden olacağından, ilgili görsellerin seçiminde gereken özen gösterilmeli; başta öğrenci seviyesine uygunluk ve bilimsellik olmak üzere ders kitaplarında yer alan görsellerin yeniden düzenlenmesi önerilmektedir.
Bütüncül Öğrenme Eğilimleri Ölçeğini Geliştirme Çalışması
Authors: BABACAN Tuğba , ACAT Mehmet Bahaddin
Published: December 2022

Araştırmada öğrencilerin bütüncül öğrenme eğilimlerini belirlemeye yönelik kullanılabilecek bir ölçme aracını geçerli ve güvenilir bir şekilde geliştirmek amaçlanmıştır. Bütüncül öğrenme eğilimleri ölçeğinin faktör yapısının belirlenmesi üzere açımlayıcı faktör analizi uygulanmıştır. AFA sonucuna dayalı olarak ölçek üç faktörlü ve on üç maddeden oluşmaktadır. “Toplumsal fayda erdemi” faktörü beş madde içermekte ve açıkladığı varyans oranı %19.792’dir. “Öz farkındalık” faktörü beş madde kapsamaktadır ve açıkladığı varyans oranı %16.118’dir. “Farklılıklara açık olma” faktörü üç madde ile biçimlenmiştir ve açıkladığı varyans oranı %11.261’dir. Üç faktörün toplamda açıkladığı varyans oranı %47.171’dir. Üç faktörlü yapı modeli, doğrulayıcı faktör analizi ile sınanmış ve hesaplanan uyum indeksleri, 2 değeri=122.18 (sd=61, p<0.000), (x2/sd)=2.00, GFI= 0.95, RMSEA=0.052, AGFI=0.93, CFI=0.94, NFI=0.89, RMR=0.019, SRMR=0.055 olarak ulaşılmıştır. Ölçeğin madde-toplam korelâsyonları, 0.28 ile 0.56 arasında ulaşılmıştır. Alt %27 ve üst %27’lik grupların madde ortalama puanları arasında yapılan t-testi sonuçlarından, tüm maddelere ilişkin farkların anlamlı olduğu belirlenmiştir. Cronbach Alpha iç tutarlılık katsayıları “toplumsal fayda erdemi” faktörü için 0.74; “öz farkındalık” faktörü için 0.62 ve “farklılıklara açık olma” faktörü için ise 0.42 olarak tespit edilmiştir. Ölçeğin tüm maddelerine ilişkin Cronbach Alpha değeri ise 0.68 olarak ulaşılmıştır. Ölçeğin geliştirilmesine ilişkin ulaşılan bulgular sonucunda geçerli ve güvenilir bir ölçeğin alana kazandırıldığı söylenebilmektedir. Bütüncül öğrenme sürecine ilişkin farklı yaş grupları için de ölçme araçlarının geliştirilmesi önerilmektedir.
PENGGUNAAN METODE DEMONSTRASI DALAM PROSES PEMBELAJARAN
Authors: Hasibuan Dirja
Published: December 2022

Penelitian ini membahas tentang implementasi metode demonstrasi sebagai suatu strategi yang diharapkan dapat meningkatkan motivasi dan hasil belajar peserta didik dalam pembelajaran pengurusan jenazah. Penelitian ini bertujuan untuk mengetahui: 1. Mengetahui implementasi metode domonstrasi untuk meningkatkan motivasi dan hasil belajar peserta didik dalam pembelajaran pengurusan jenazah di SMKN 1 Lubuk Pakam. 2. Mengetahui hasil belajar peserta didik dalam pembelajaran pengurusan jenazah di SMKN 1 Lubuk Pakam. 3. Mengetahui motivasi belajar peserta didik  dalam pembelajaran pengurusan jenazah di SMKN 1 Lubuk Pakam. 4. Mengetahui seberapa besar keberhasilan implementasi metode demonstrasi dalam meningkatkan motivasi dan hasil belajar peserta didik dalam pembelajaran pengurusan jenazah di SMKN 1 Lubuk Pakam. Penelitian ini merupakan penelitian lapangan atau tindakan, dengan jenis penelitian tindakan kelas (action research). Hal ini dapat dibuktikan dengan pengumpulan data yang diperoleh langsung dari observasi, wawancara, kuesioner atau angket, kajian dokumen, diskusi antara guru, teman sejawat, dan kolaborator  kemudian di deskripsikan sebagaimana adanya dalam bentuk kalimat yang dapat memberikan makna dari apa yang akan di teliti. Dari hasil penelitian menunjukkan bahwa aktivitas peserta didik cenderung meningkat meskipun ada beberapa aktivitas yang tidak relevan, memperhatikan, mendengar penjelasan guru menunjukkan aktivitas yang tinggi, sama halnya  aktivitas peserta didik pada indikator menanggapi pertanyaan guru-pendapat guru, menanggapi pernyataan, pendapat peserta didik lain, mengajukan pertanyaan, bekerjasama dalam kelompok, menyatakan ide dengan jelas, juga merupakan indikator aktivitas peserta didik yang tinggi.
PERBAIKAN ETIKA ANAK MELALUI METODE BERCERITA DI RA ABDULLAH KOTA PADANGSIDIMPUAN
Authors: Mardiah Mardiah , Irwansyah Irwansyah
Published: December 2022

Etika adalah  aturan prilaku, adat kebiasaan manusia dalam pergaulan antara sesamanya dan menegaskan mana yang benar dan mana yang buruk.  Bercerita adalah menuturkan sesuatu yang mengisahkan tentang perbuatan atau sesuatu kejadian dan disampaikan secara lisan dengan tujuan membagikan pengalaman dan pengetahuan kepada orang lain.  Penelitian ini bertujuan untuk mengetahui perbaikan etika anak melalui metode bercerita di RA Abdullah Kota Padangsidimpuan . Metode yang  diterapkan dalam melakukan penelitian ini adalah metode kualitatif, alat pengumpul data dalam penelitian ini adalah wawancara, observasi dan studi dokumen. Dalam proses pembelajaran, metode menduduki  posisi yang sangat penting, oleh karena itu seorang guru tidak cukup hanya menguasai satu metode saja. Sebab dengan menguasai berbagai metode ia akan mampu menentukan penggunaan metode tersebut sesuai dengan  kondisi siswa. Salah satu metode yang tepat dalam menerapkan etika pada  anak tingkat usia dini adalah metode bercerita, hal ini menunjukkan bahwa melalui cerita yang disampaikan oleh guru murid secara tidak langsung dapat mengambil nilai-nilai pendidikan terkait dengan etika atau moralitas dari cerita tersebut. Hasil dari penelitian ini menunjukkan bahwa kondisi atau keadaan anak umur nol samapai dengan enam tahun cenderung  menerima dan mencontoh. Sehingga apapun yang diajarkan oleh guru akan lebih mudah  diserap, bercerita juga sesuai dengan perkembangan kognitif anak. Cara-cara dalam menerapkan etika pada anak adalah melalui pelatihan. Seperti bagaimana cara makan yang baik, bersikap empati,  atau cara mengucapkan kata-kata yang baik. Seperti halnya “terima kasih, dll. Sehingga melalui metode bercerita akan lebih mudah dalam menerapkan etika pada anak.
Hybrid Deep-GAN Model for Intrusion Detection in IoT Through Enhanced Whale Optimization
Authors: Balaji S. , Sankara Narayanan S.
Published: December 2022

IoT networks emerging as a significant growth in modern communication technological applications.  The network formed with sensor nodes with resource restrictions in complexity, open wireless transmission features lead them prone to security threats. An efficient Intrusion Detection System aids in detecting attacks and performs crucial counter act to promise secure and reliable function. However, for the reason of the widespread nature of IoT, the intrusion detection system is supposed to carry out in discrete form with fewer fascination on common manager. In order to conquer these issues, Distributed – Generative Adversarial Network (D-GAN) with Enhanced Whale Optimization – Distributed deep learning based on Artificial Neural Network (EWO-HDL+ANN) is proposed. Here the GAN can detect internal attacks and the D-GAN is capable of detecting both internal and external attacks effectively. Transfer By Subspace Similarity is engaged to carry out. After that the preprocessed data is fed into feature extraction stage. Modified Principal Component Analysis (MPCA) is applied to feature extraction, which is used to extract new features that are enlightened. Then, feature selection is executed by Enhanced Whale Optimization Algorithm, which is used to choose significant and superfluous features from the dataset. It gets better the classification accuracy through the greatest fitness value. Then the intrusion detection is evaluated by applying HDL+ANN algorithm used to detect the attacks powerfully. The experimental conclusion proves that the introduced EWO-DDL+ANN method provides enhanced intrusion detection system in the view of greater accuracy, precision, recall, f-measure and low False Positive Rate.
Composición y comportamiento inicial de malezas precoces en sustrato con plantas de Solanum lycopersicum L. en Satipo
Authors: Alomia - Lucero José manuel , Baltazar - Ruíz Milciades Anibal , Estrada - Carhuallanqui Hebert Nino , Cañari - Contreras Miriam Dacia , Castro - Garay Angelica
Published: December 2022

Las malezas en el trópico por el clima caluroso, húmedo y lluvioso en 30 días cubren el 100% de la superficie del suelo en contra de las plantas cultivadas; no hay estudios sobre la dinámica de las malezas en tomate que nos permitan entender para evitar el uso de herbicidas. Se ha trabajado con 12 javas de tierra agrícola expuestos a la intemperie con los riegos y la lluvia; las plantitas fueron contadas y pesadas por especie y familia a los 30 días; se extrajo plantas con raíz agrupando por especie y se pesó en una balanza digital gramera; los datos fueron procesados en excel con fórmulas para el porcentaje y las cantidades por m2 . Se han registrado 12 especies de malezas, de estas cuatro forrajeras, tres comestibles, tres antibióticos, uno medicinal y uno nematicida; Phyllantus niruri L. fue la más abundante con 80,4 individuos por m2 (27,93%); Euphorbia heterophylla es la más pesada en materia verde con 106,43 g/m2 (28,68%); las euforbiáceas son más abundantes en número de especies por familia, con tres especies que representan el 25%; las poáceas son las más abundantes por m2, con 84,89 individuos ( 29,5%); las euphorbiáceas son las más pesadas con 196,16 g/m2 (51,8%). Lo más importante fue encontrar una diversidad de malezas precoces en los 30 primeros días en una abundancia que cubren el 100% de la superficie del suelo, lo que ayudó a extraer las plantas de cada java, identificarlas, contarlas y pesarlas.
Investigation of Global Warming Case of Antalya
Authors: ARSLAN Onur
Published: December 2022

Antalya is one of the most important cities of Turkey in terms of agriculture, tourism and population. In this study, the global warming case of Antalya was investigated by using the monthly mean maximum, monthly mean minimum and monthly mean temperature data of Elmalı, Korkuteli, Antalya, Manavgat and Gazipaşa meteorology stations between 1970 and 2017. For this aim, trend analyses were performed by Mann Kendall Rank Correlation method and beginnings of trends were determined. Run, interquartile range and autocorrelation tests were applied before trend analysis test. 99.99% confidence interval was used for all tests. Run test results indicated that the data is homogenous. According autocorrelation test results, there is not autocorrelation in tha data except monthly mean minimum temperature data of Antalya station for August. Therefore, prewhitening was used for monthly mean minimum temperature data of Antalya station for August. The 12-month average value of the increasing trend was calculated as 98.33% for the mean temperature, 88.33% for the mean maximum temperature and 80% for the mean minimum temperature. The 12-month average value of the statistically significant increasing trend was calculated as 10% for the mean temperature, 5% for the mean minimum temperature and 0% for the mean maximum temperature. If 95% confidence level was used for Mann-Kendall test, the 12-month average value of the statistically significant increasing trend was calculated as 61.9% for the mean temperature, 34.5% for the mean maximum temperature and 51.2% for the mean minimum temperature. These results show that there is global warming in Antalya. The beginnings of statistically significant trends vary between 1992 and 2009. While water consumption is increasing due to increase in agriculture, tourism and population in Antalya, the global warming detected in this study shows that both water consumption and losses in water resources will increase further. Precautions are suggested in the results section.
Evaluation of the Performance of ANN Algorithms with the Bidirectional Functionally Graded Circular Plate Problem
Authors: DEMİRBAŞ Munise Didem , ÇAKIR (SOFUOĞLU) Didem
Published: December 2022

Functionally graded materials (FGMs) are materials composed of metals and ceramics in which the distribution of material components varies according to a particular volumetric function. FGMs are often used in high-temperature applications. In our study, models were created in the Artificial Neural Network depending on the equivalent stress levels in the compositional gradient exponent, which is the most important parameter in determining the thermo-mechanical behavior of circular plates functionally staggered in two directions, and the performances of these models were evaluated. These models were obtained with four different training algorithms: Levenberg-Marquardt, Backpropagation Algorithm, Resilient Propagation Algorithm, Conjugate Gradient Backpropagation with Powell-Beale Restarts To train the ANN, equivalent stress levels were obtained by performing numerical analyzes at different compositional gradient upper values. The data sets were created by considering the largest value of the equivalent stress levels, the smallest value of the largest value, the largest value of the smallest value, and the smallest value of the smallest value. In this study, training stages and performance values were examined and interpreted with 4 training algorithms in detail.
Experimental Analysis of Pneumatic Motion Control Application with Piezo Technology
Authors: GÜNDOĞAN TÜRKER Çiğdem , AKYÜZ Fikret
Published: December 2022

Piezo technology is used in a large number of sectors thanks to the possibility of switching between electrical energy and motion energy. In particular, Piezo technology provides an important advantage in pneumatic applications with its features such as low energy consumption, accuracy, quiet operation, compact structure, fast switching possibility, quiet operation and lightness. Directional control, proportional pressure control, proportional flow control, positioning, soft-stop and similar basic applications are being transformed into controlled and digitalized Pneumatic System applications. In this paper, piezovalves developed using piezoceramic material are compared with solenoid valves in pneumatic applications. The working methods and advantages of piezo technology in pneumatic applications such as pressure control, flow control, motion control are presented. The experimental test device with a pneumatic cylinder working with piezo valves and position sensors was installed and motion control application was performed. In the experimental results of the application, the system characteristics can be observed graphically and the results can be analyzed.
A PARTICIPAÇÃO DE ENFERMEIROS RESIDENTES EM ESTRATÉGIAS PARA O ALCANCE DOS INDICADORES DO PREVINE BRASIL
Authors: Portela Alan Diego de Jesus , Lopes Donátila Cristina Lima , Oliveira Gleyceane Pinheiro de , Silva Gilson Fernandes da , Nogueira Jeanne Gomes da Silva , Cavalheiro Raiana Friedrich
Published: December 2022

Introdução: As instabilidades e as restrições orçamentárias vivenciadas recentemente inviabilizam o alcance dos objetivos constitucionais, o que demandou uma revisão da alocação dos recursos. Em 2019, adotou-se um novo modelo de financiamento da Atenção Primária à Saúde, o Previne Brasil. Objetivo: refletir sobre a influência do Programa de Residência Multiprofissional em Saúde da Família (PRMSF) sobre os indicadores de saúde do novo financiamento da APS, no acesso aos serviços e assistência oferecidos aos usuários em Unidades de Saúde da Família (USF) de Cascavel/PR. Metodologia: estudo descritivo e qualitativo, do tipo relato de experiência, baseado nas estratégias gerenciais e assistenciais realizadas entre março e setembro de 2022, nas Unidades de Saúde da Família (USF) utilizadas como campo de prática, em Cascavel, Paraná. Resultados e Discussões: as ações diante do indicador 1 se mostraram eficazes, produzindo maior participação das gestantes no processo do cuidado e aumento do comparecimento às consultas de pré-natal; as implementadas para o rastreio do câncer de colo uterino contribuíram para o aumento da procura pelo exame; para os indicadores 6 e 7, referente ao cuidado continuado de hipertensos e diabéticos, resultaram na atualização cadastral e motivou a retomada do gerenciamento da saúde desse público. Considerações finais: as estratégias contribuíram para o pensamento crítico, raciocínio clínico e gerenciamento do cuidado. Todavia, observou-se que o Previne Brasil impactou na assistência integral, formação, tempo de atendimento e na escuta ativa, devido a priorização dos números em detrimento à qualidade.
A Study on Investment Behaviour of Working Women with Reference to Irinjalakuda Municipality
Authors: Shamy. C. Shaji
Published: December 2022

Working women want to be financially independent & secure. They want to invest their money & savings to handle critical situations at any stage of their lives. This research study is based on the analysis of income and investment behaviour of the working women in India. The study was conducted on working women in both government and private sectors in India. The data has been analysed using frequency analysis, descriptive statistics, percentage and person correlation coefficient analysis with the help of statistical software.
UJI DAYA HAMBAT MADU HUTAN BADUY SEBAGAI SUBSTRAT PADA BUNGA TELANG (Clitoria ternatea L) MELALUI METODE BIOTEKNOLOGI FERMENTASI KOMBUCHA DALAM MENGHAMBAT PERTUMBUHAN BAKTERI PATOGEN
Authors: Kusumiyati Kusumiyati , Setyaji Diyan Yunanto , Fadillah M Fariz , Rezaldi Firman
Published: December 2022

Telang flower (Clitoria ternatea L) fermented by kombucha is a probiotic drink produced by a consortium of bacteria and yeast. The raw material in this kombucha fermentation is in the form of telang flowers that have been cold from the previous boiling process. This study aims to determine the antibacterial activity of telang flower kombucha with different concentrations of Baduy forest honey. The concentration of Baduy forest honey consisted of 20%, 30%, and 40% (w/v) where each treatment was repeated 3 times. The positive control used in this study was kombucha made from green tea. Sterile aquadest is a treatment positioned as a negative control. The disc diffusion method is one of the methods used in antibacterial testing by measuring the diameter of the inhibition zone. Telang flower kombucha fermentation has activity as a broad-spectrum antibacterial source. This can be indicated by the potential to prevent the growth of Staphylococcus aureus, Staphylococcus epidermidis, Pseudomnonas aeruginosa, and Escherichia coli bacteria. Baduy forest honey concentration of 40% is the best concentration in fermented kombucha flower telang as an antibacterial and has the potential as the latest functional drink from fermented biotechnology products.
Hükümlü veya Tutuklunun Kaçması Suçu (Tck M. 292-293)
Authors: Aksan Murat
Published: December 2022

Bu çalışmada hükümlü veya tutuklunun kaçması suçu ele alınmıştır. Bu suç, TCK’nın Adliyeye Karşı
Suçlar bölümünde 292. ve 293. maddelerinde düzenlenmiştir. 292. madde düzenlemesinin 1.
fıkrasında suçun temel hali (sadece kaçma), 2. fıkrasında suçun cebir veya tehdit kullanılarak
işlenmesi, 3. fıkrasında ise silahlı olarak ya da birden çok tutuklu veya hükümlü tarafından birlikte
işlenmesi nitelikli hal olarak öngörülmüştür. 4. fıkrasında içtimaya ilişkin özel hüküm sevk edilmiş, 5.
fıkrasında ise ceza infaz kurumu dışında çalıştırılan hükümlüler ile hapis cezası adlî para cezasından
çevrilmiş olanların kaçma suçunu işleyebilecekleri hüküm altına alınmıştır. 293. maddede ise etkin
pişmanlık kurumuna yer verilmiştir. Çalışmada bütün bu haller detaylı bir şekilde incelenmiştir. Hangi
hallerde kaçma suçunun oluşacağı ve hangi hallerde nitelikli hallerin uygulanacağı, teşebbüs, iştirak,
içtimaya ilişkin oluşabilecek durumlar ve etkin pişmanlık kurumu doktrindeki görüşler ve Yargıtay
kararları çerçevesinde incelenmiştir.
Effect of skipping breakfast on cognition and learning in young adults
Authors: Dutta Pritika , K. Ramdas Nayak Vineetha
Published: December 2022

Introduction and Aim:  Consumption of breakfast has been commonly associated with cognitive parameters among school children and adolescents. The current cross-sectional study was conducted with the aim to investigate the effect of breakfast consumption/omission on cognitive functioning and learning among young adults.

 

Materials and Methods: Sixty college-going students, divided into two groups such as breakfast consumers and breakfast skippers were asked to fill a physical condition-based study questionnaire. The results of which were assessed along with the performances given in a collective cognition-based task. The obtained data was retained and later analyzed by GraphPad Prism (version 5).

 

Results: The overall performance, attentiveness, response time and alertness were significantly higher among the college-going breakfast consumers when compared to breakfast skippers thereby highlighting the importance of daily consumption of breakfast among young adults.

 

Conclusion: Breakfast consumption is of paramount importance among college going students, omission of which could influence cognitive performances and behavioral aspects. Hence, academic programs should promote nutritionally balanced breakfast consumption among college students.
The role of resistin gene polymorphism in Iraqi breast cancer patients
Authors: A. Sahan Khadija , H. Aziz Ismail , Nadhir Dawood Sanna , Al Qazzaz Hasen
Published: December 2022

Introduction and Aim: Breast cancer is a complex disease and one of the most common cancers among women. Breast cancer is linked to a number of inherited gene alterations which could either initiate breast tumors or be involved in the multistage process of breast cancer development. In this study we aimed to genotype the resistin (RETN) gene linked to breast cancer and determine the effects of RETN single nucleotide polymorphisms (rs3219175, rs34788323) to breast cancer in Iraqi women.

 

Materials and Methods: This study included 70 (35 malignant and 35 benign) patients with breast cancer and 35 breast-cancer free Iraqi women. Blood samples were collected from all women and subjected to two RETN SNPs (rs3219175, rs34788323) genotyping and determining their allelic frequencies. The serum resistin concentration was determined for each sample. Data was subjected to statistical analysis and p-value determined.

 

Results: A statistically significant difference for the GA genotype in SNP rs3219175 and TT genotype in SNP (rs34788323) was seen among breast cancer patients, and controls. among Iraqi women. The mean resistin concentration was substantially greater in the malignant group (4,194 ng/ml) compared to the benign group (1,651 ng/ml) and the control group (1,476 ng/ml) (P 0.01). The rs34788323 polymorphism's CC genotype could be associated with higher resistin levels. The blood resistin level was substantially greater in breast cancer patients with the AA genotype (7.710 0.57ng/ml) than in benign (2.340 0.24ng/ml) or control group (2.231 0.15ng/ml), although the difference was not statistically significant, according to rs3219175 SNP results. The incidence of breast cancer was 42.85% higher in the middle age group (40-49 years). The study did show a detrimental relationship between BMI and tumour size, stage, and grade.

 

Conclusion: Results indicate a correlation between retn gene polymorphism, resistin serum levels and breast cancer susceptibility.
TEMEL EĞİTİMDE GÜNCEL SORUNLAR VE ÇÖZÜM ÖNERİLERİ
Authors: ZÜNGÜR Ercüment
Published: December 2022

Eğitim, İlk canlıdan başlayan ve yaşam var olduğu müddetçe varlığını sürdürecek olan dinamik bir yapıdır. Bu dinamik sistemi oluşturan ve onu birbiriyle bir bütün şeklinde tamamlayan hareketli parçaları olası bir şekilde irdelenip çözümlenmelidir.
Eğitimi analiz ederken ayaklarından olan öğretmen, öğrenci, veli, eğitim politikası, eğitim felsefesi, eğitim programı, okul kültürü, okul yöneticisi ve hükümet politikalarını işin içine dâhil etmeliyiz. Eğitim sorunları sabit değildir, eğitimi dinamik bir süreç olarak tanımlarken sorunlarının da bu dinamikliğe paralel olarak karmaşık olduğunu unutmamalıyız. Birbirini tamamlayan bu yapbozlu sistemde bir parçanın bozulması ya da gereken önemin verilmemesi diğer parçaları da etkileyecektir. Bir çocuğun eğitiminin temelinde aile olsa da devamında okul öncesinde verilen eğitim ilkokulu, ilkokulda verilen eğitim ortaokul kademesini ciddi bir şekilde etkileyecektir. Bu etkilenme burayla sınırlı kalmayacaktır ve devamında ortaöğretimi, yüksek öğretimi ve en önemlisi yaşadığı toplumu, toplun geleceğini ciddi bir şekilde etkileyecektir. Peki, bu sorunlar nelerdir? Sorunların temeline inildiğinde uygulanan eğitim politikalarından, geliştirilen eğitim programlarından, benimsenen eğitim felsefelerinden, öğrenci ve öğretmenlerin nitelik düzeylerinden, eğitimde uygulanan yönetim stratejilerinden kaynaklanan sorunlar karşımıza çıkmaktadır. Eğitimin olmazsa olmaz ayaklarından olan bu işlevleri yok saymak ve temelini sağlam oturtturmamak ilerde önüne geçilemeyecek sorunların baş göstermesine sebebiyet verecektir. Eğitimi bir basamak şekilde grafikleştirirsek tüm bileşenlerinin bir yapboz gibi birbirini tamamlaması gerektiğini bilmeliyiz. Yaptığımız bu araştırma ile amacımız finalde toplumu etkileyen bu sorunlara değinip ve çözümleri konusunda fikirler sunmaktır.
OKUL ÖNCESİ DÖNEMDE KAYNAŞTIRMA ÖĞRENCİLERİNİN ÖĞRETMENİN VERİMLİLİĞİNE ETKİSİNİN İNCELENMESİ
Authors: TURHAN İmran , YILDIRIM Sait , GÜLBETEKİN Eda
Published: December 2022

Bu çalışmanın amacı kaynaştırma eğitime ihtiyaç duyan çocukların içinde yaşadığı toplum ve çevreye uyum becerileri kazanmalarına yardımcı olmak; aynı zamanda bu kaynaştırma eğitimi ile özel gereksinimli bireylerin küçük yaşlardan itibaren kendi akranları ile aynı ortamda bulunarak toplumda birbirinden farklı özelliklere sahip kişilere saygı göstermek özel gereksinimli bireylerin sosyal kabulünde artış sağlayacaktır. Kaynaştırma programı ve eğitimlerinin amacına ulaşmasında en etkili kişi olan öğretmenlere büyük görevler düşmektedir. Okul öncesi eğitim kurumlarında kaynaştırma öğrencilerinin öğretmen verimliliğine etkisini incelemek ve karşılaşılan güçlükleri tespit etmek amacı ile Iğdır il genelinde 17 anaokulunda 126 öğretmene kaynaştırma eğitimi ile ilgili duygular tutumlar ve kaygılar ölçeği anketi uygulanmıştır. Yapılan çalışma için Etik Kurul belgesi alınmış olup nicel araştırma yöntemi kullanılmıştır. Ayrıca araştırmadan sağlanan verilerin SPSS v.23 analiz programı kullanılarak yapılan istatistiksel analiz sonuçları verilmiştir. Çalışmada yer alan öğretmenlerin %83,3’ü (105) kadın, %16,7’si (21) erkektir. Öğretmenlerin %79,4’ü (100) il merkezinde, %15,1’i (19) ilçe merkezinde ve %5,6’sı (7) köyde görev yapmaktadır. Cronbach Alpha güvenirlik katsayısı 804, “Tutum” alt boyutunun Cronbach Alpha güvenirlik katsayısı 738 ve “Kaygı” alt boyutunun Cronbach Alpha güvenirlik katsayısı 638 olarak tespit edilmiştir. “Duygu” alt boyutunun puan ortalaması (12,14±3,024), “Tutum” alt boyutunun puan ortalaması (12,73±2,214) ve “Kaygı” alt boyutunun puan ortalaması (13,44±2,787) orta düzeyde olduğu söylenebilir. Öğretmenler genellikle kaynaştırma eğitimine karşı olumsuz tutum göstermektedirler. Bunun nedeni ise özel eğitime muhtaç çocuklar ve ihtiyaçları konusunda yeterli bilgiye sahip olmamalarıdır. Bu durum öğretmenlerde kaygıya yol açmakta ve sınıf içindeki verimliliğini olumsuz yönde etkileyebilmektedir. Kaynaştırma programı ve uygulanacak eğitiminin amacına ulaşabilmesi ve öğretmen tutumlarının olumlu yönde değiştirilmesi için Millî Eğitim Bakanlığı tarafından merkezi ve mahalli olarak düzenlenecek hizmet içi kurs ve seminer çalışmalarında, öğretmenleri özel eğitime muhtaç çocuklar ve ihtiyaçları konusunda yeterli düzeyde bilinçlendirme öğretmenin verimliliğini olumlu yönde arttıracaktır.
SYNTHESIS OF NOVEL BIS(PHOSPHINO)AMINE-RUII(ACAC)2 COMPLEXES, AND INVESTIGATION OF CATALYTIC ACTIVITY IN TRANSFER HYDROGENATION
Authors: ELMA KARAKAŞ Duygu , IŞIK Uğur , AYDEMİR Murat , DURAP Feyyaz , BAYSAL Akın
Published: December 2022

In this study, reactions of (PPh2)2NCH2CH2N(PPh2)2 (L1) and {(PPh2)2NCH2CH2}3N (L2) with [RuII(acac)2(CH3CN)2] led to the production of new dinuclear complex [Ru(acac)2]2(L1) (1) and trinuclear complex [Ru(acac)2]3(L2) (2). Complex 1 and 2 are excellent candidates for the role of catalyst precursors in the transfer hydrogenation (TH) of acetophenone and its derivatives. Compared to complex (1), the trinuclear complex (2) is an exceptional catalyst, producing the corresponding alcohols in 98–99% yields in 20 minutes at 80 oC (TOF≤300 h-1) for the TH process. A comparison of the catalytic properties of the complexes is also briefly discussed. Complex structures have also been characterized by combining nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR), and elemental analysis.
A density functional study of the coronene-pyrrole system in relation to its possible application as NO2 and NH3 sensors
Authors: Olmedo-Martinez Cinthya Susana , Hernandez-Duarte Jesus Moises , Mejia-Olvera Roberto , Pacheco-Ortin Sandy Maria , Agacino-Valdes Esther
Published: December 2022

According to recent research on the application of graphene materials as sensors and particularly polypyrrole-graphene materials, which are especially promising, the functionalization of graphene with a pyrrole molecule might be considered a viable alternative as a NO2 and NH3 sensor. In this way, a graphene sheet simulated as a coronene molecule was used in order to test whether this kind of functionalization could be useful for detecting the NO2 and NH3 toxic gases with a relatively high sensitivity. NO2 was studied as an example of an electron acceptor molecule, and NH3 as an electron donor molecule. Both molecules were adsorbed on two different regions of the functionalized adsorbent, and the energy ranges found for adsorption were reported and compared with those of the pristine graphene. The results indicated that in the coronene-pyrrole system, pyrrole tends to lie almost parallel to the coronene sheet in a π-π stacking interaction between the two conjugated systems, being the closest distances of 3.0 and 3.2 Å. The use of Δ (ΔHOMO-LUMO) as a descriptor confirmed that the coronene-pyrrole system is a good option as a NO2- and NH3-sensor; therefore, it might be an easy and suitable descriptor for characterizing the performance of a sensor; all calculations were made using a Density Functional formalism, through a functional M06-2X in combination with the 6-31G(d,p) basis set.
Alendronate functionalized PLGA based nanoparticles for the effective treatment of osteoporosis-Formulation to in-vitro release kinetic studies
Authors: Pathak Sandhya , Shukla Sandeep , Patel Bharat , Tripathi Satyendra Kumar , Pandey Archna
Published: December 2022

Osteoporosis is a bone disease caused due to the reducing bone mineral density. Porous and more fragile bones increase the risk of fractures. Hip, spine, shoulder, and wrist bones are commonly affected by osteoporosis. Low bone density is a leading cause of osteoporosis. The most efficient prescribed drugs for the treatment of osteoporosis are bisphosphonates drugs. Alendronate was the first FDA approved bisphosphonate drug for the treatment of osteoporosis. Osteoclast cells are the primary targeting site for alendronate, responsible for bone resorption. A biopharmaceutical classification system class III bisphosphonate acts as a potent, efficient, and bone resorption inhibitor drug. In the present study, alendronate functionalized PLGA based nanoparticles were developed by a solvent diffusion method and optimized for different process variables. The formulated nanoparticles were characterized for surface morphology, particle size distribution, surface charge and drug-polymer compatibility. The scanning electron microscopy and transmission electron microscopy results showed nanoparticle size in the range below 200 nm. The average particle size and zeta potential of the formulated nanoparticles were found to be 175.3 nm and -13.98 mV, respectively. The highest encapsulation efficiency was 65.23%. The release profile was dissolution medium dependent and followed by the Higuchi model of release kinetics.
Exploration of the Effect of Carbon Fiber Ratio and Dimensions on Electrical Conductivity in Mortars
Authors: UZUNALİOĞLU Hacer , YAZICIOĞLU Salih , AHISKALI Adem , ÇAĞLAR Hakan
Published: December 2022

This study was carried out on Class F and C fly ash reinforced, carbon fiber added mortar samples as a substitute for PÇ42,5 cement. Carbon fiber was added in different sizes at rates of 0.5%, 1%, and 3% in order to investigate the effects of the size and ratio of carbon fiber on electrical conductivity. 33 different series were formed such as obtained Class F; without fly ash 10%, 20% and Class C; without fly ash, 10%, 20% with samples without carbon fiber and with carbon fiber having dimensions 5 mm and 10 mm. The water/cement ratio was prepared to take the value of 22-23cm in the flow table test.,A viscosity regulator of 0.1% of the fine material was used in order to ensure homogeneous distribution of carbon fiber in the mortar. 3 samples were prepared for each series in order to reduce the margin of error. Electrical conductivity, compressive and tensile strength tests were applied to the oven dry and naturally moist conditions of the samples that completed their 7, 28 and 56 days curing periods. Increasing the carbon fiber size increased the tensile strengths and increasing the carbon fiber ratio increased the tensile strengths. It has been observed that carbon fiber increases the electrical conductivity, but the conductivity decreases depending on time, and as the sizes and proportions of the carbon fiber fibers increase, the compressive strength decreases due to the void effect in the mortar, while the compressive strength increases with the increase in the fly ash ratio. The microstructure and carbon fiber distribution of the samples were examined using SEM (Scanning Electron Microscopy) and it was seen that the carbon fiber distribution was in a way that supports the electrical conductivity measurement. The study allowed the size and proportion effect of carbon fiber in mortars to be compared with C and Class F reinforced mortar samples.
Peningkatan Performa Teknis dan Ekonomi Peternakan Ayam Lokal IPB D1 yang Diberikan Tepung Larva Black Soldier Fly
Authors: Sembada Pria , Ayuningtyas Gilang , Priyambodo Danang , Kurniawan Fariz Am , Dewi Sari Putri , Kusumanti Ima , Inayah Asty Khairi , Wibiksana Fikri , Syahfitri Annisa Eka Nur
Published: December 2022

Food loss and waste (FLW) and dependence on imported feed ingredients need to be resolved comprehensively. Bioconversion using the Black Soldier Fly (BSF) maggot is applicable to overcome this problem. This study aims to examine the technical and economic performance of IPB D1 local chickens fed BSF maggot in their rations. This study used a completely randomized design (CRD) to observe differences in the production and economic performance of 515 birds (IPB D1). Three treatments (P0, P1, and P2) were observed for ten weeks. BSF maggot meal cost production, production performance, and economic performance were observed in this study. The data were analyzed using descriptive and statistical analysis. The main findings of this research indicated the potential of maggot meal as an alternative source of protein in local chicken rations. Feed efficiency and production performance of IPB D1 chickens given P1 and P2 rations could compete with rations using other protein sources. The economic performance also shows the same thing. However, there are high–economic costs for producing maggot meal. Furthermore, the benefits value by rations P1 and P2 were relatively small compared to control rations. Based on technical and economic performance, maggot meal needs to be developed as a local chicken ration ingredient. However, innovation is necessary to reduce production costs and increase profitability.
SIKINTIYA DAYANMA DÜZEYİ VE TOLERANS İLİŞKİSİ: ÇAĞRI MERKEZİ ÇALIŞANLARI ÜZERİNE KESİTSEL BİR ARAŞTIRMA
Authors: ERDOĞAN Adeviye
Published: December 2022

Çalışmada, çağrı merkezi çalışanlarının sıkıntıya dayanma düzeyleri ve toleransları arasındaki ilişki araştırılmaktadır. Çağrı merkezi çalışanları birçok araştırmanın konusu olmuştur. Bu çalışmalar çağrı merkezi çalışanlarının yoğun stres altında olduğunu, iş yükleri ile çalışma sürelerinin fazla olduğunu ve uzun süreli kurdukları iletişimden dolayı da “sıkıntı” yaşadıklarını ortaya koymaktadır. Sıkıntıya dayanma düzeyi fazla olan çalışanların toleranslarının da yüksek olacağı düşüncesi bu çalışmanın çıkış noktasını oluşturmaktadır. Alan yazında sıkıntıya dayanma düzeyi ile toleransı birlikte ele alan bir çalışmaya rastlanmamıştır. Çalışmanın stres düzeyi yüksek olan çağrı merkezi çalışanları üzerinde yapılıyor olmasının da anlamlı olduğu değerlendirilmektedir. Çalışma kapsamında verilerin toplanması için geçerlik ve güvenirlik çalışmaları yapılmış olan “Sıkıntıya Dayanma Ölçeği” ve “Tolerans Ölçeği” ve demografik özelliklerin belirlendiği sorular kullanılmıştır. Araştırmada 293 çağrı merkezi çalışanına ulaşılmıştır. Örneklem bağlamında yapılan analizler sonucunda çağrı merkezi çalışanlarının sıkıntıya dayanma düzeyleri ve toleransları arasında pozitif yönlü ve düşük düzeyli ilişki bulunmuştur. Araştırmanın alan yazına önemli bir katkı sağlayacağı öngörülmektedir.