bluuebunny/crossref_metadata_2025 huggingface dataset:
Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation
Authors: Dolliver Stacia M. , Kleer Mariel , Bui-Marinos Maxwell P. , Ying Shan , Corcoran Jennifer A. , Khaperskyy Denys A.
Published: December 2022

Stress granules (SGs) are cytoplasmic condensates that often form as part of the cellular antiviral response. Despite the growing interest in understanding the interplay between SGs and other biological condensates and viral replication, the role of SG formation during coronavirus infection remains poorly understood. Several proteins from different coronaviruses have been shown to suppress SG formation upon overexpression, but there are only a handful of studies analyzing SG formation in coronavirus-infected cells. To better understand SG inhibition by coronaviruses, we analyzed SG formation during infection with the human common cold coronavirus OC43 (HCoV-OC43) and the pandemic SARS-CoV2. We did not observe SG induction in infected cells and both viruses inhibited eukaryotic translation initiation factor 2α (eIF2α) phosphorylation and SG formation induced by exogenous stress. Furthermore, in SARS-CoV2 infected cells we observed a sharp decrease in the levels of SG-nucleating protein G3BP1. Ectopic overexpression of nucleocapsid (N) and non-structural protein 1 (Nsp1) from both HCoV-OC43 and SARS-CoV2 inhibited SG formation. The Nsp1 proteins of both viruses inhibited arsenite-induced eIF2α phosphorylation, and the Nsp1 of SARS-CoV2 alone was sufficient to cause a decrease in G3BP1 levels. This phenotype was dependent on the depletion of cytoplasmic mRNA mediated by Nsp1 and associated with nuclear accumulation of the SG-nucleating protein TIAR. To test the role of G3BP1 in coronavirus replication, we infected cells overexpressing EGFP-tagged G3BP1 with HCoV-OC43 and observed a significant decrease in virus replication compared to control cells expressing EGFP. The antiviral role of G3BP1 and the existence of multiple SG suppression mechanisms that are conserved between HCoV-OC43 and SARS-CoV2 suggest that SG formation may represent an important antiviral host defense that coronaviruses target to ensure efficient replication.
The expanding beauty regime: Or, why it has become so important to look good
Authors: Kuipers Giselinde
Published: December 2022

In contemporary societies, physical appearance is more important to more people than ever before. This article sketches the expansion of this contemporary beauty regime. Drawing mainly on European data, I argue that since the late 1800s the societal importance of appearance grew, as a result of expanding media and consumer cultures, social democratization, a shift to a service-based economy and the rise of new media. People came to have more developed and diverse tastes in human beauty and more opportunities to cultivate their appearance. It became more important to be beautiful, for men and women, across the course of life, in more domains of life. Drawing on the tradition of process sociology inspired by Weber and Elias, I interpret this gradual raising of cultural standards as the emergence of a beauty regime involving new standards for social control and self-control, standards for moral and aesthetic evaluation and standards for social worth and self-worth. The beauty regime is demanding and constraining for individuals but contributes to the emergence of durable social constellations that people might consider progress. The beauty regime makes appearance more central to many domains of life, and thus more consequential for identities and inequalities, self-worth and social worth.
Slogan T-shirts: Liberalism, abolition and commodity activism in the Midwestern United States
Authors: Gebhart Nancy , Reddy-Best Kelly L.
Published: December 2022

Wearing slogan T-shirts largely began in the United States in the mid-twentieth century with the rise of various social movements. Considering the persistence of slogan T-shirts as a component of commodity activism, we theoretically engage with the ways twenty-first century organizations produce slogan T-shirts within the fashion system, with heightened attention to white progressive politics. We examine two Midwestern organizations in the United States: Raygun, which approaches T-shirt activism as a for-profit business and For Everyone Co., which approaches T-shirt activism as a not-for-profit collective. We conduct a case study to examine the nuance of how and why these collective and for-profit businesses use T-shirt activism, drawing upon multiple theoretical concepts to critically interpret the production and distribution of these products within the fashion system and offering theoretical implications for future study. We conduct a close reading of T-shirt texts and images, the organizations’ biographical information, and their reported philanthropic actions to construct and interpret their public-facing narratives engaging with fashion and activism. Examining T-shirt activism, as both an ‘artivist’ practice and a commodity, requires a critical analysis of how organizations capitalize on consumers’ desire and instances wherein white progressive politics prioritize the appearance of equity and justice or ambiguous fashion activism, over meaningful social-action centred fashion. Our work offers implications for the production, distribution and consumption of these products within the fashion system.
Black Designers in American Fashion, Elizabeth Way (ed.) (2021)
Authors: Romano Alexis
Published: December 2022

Review of: Black Designers in American Fashion, Elizabeth Way (ed.) (2021)

London and New York: Bloomsbury Visual Arts, 267 pp.

ISBN 978-1-35013-847-6, p/bk, $34.95 / £24.99

ISBN 978-1-35013-850-6, online, $31.45 / £22.49

ISBN 978-1-35013-848-3, e-book, $31.45 / £22.49
Transcultural curation and the post-COVID world
Authors: Querol Nuria
Published: December 2022

New and complex forms of entanglements and power dynamics have taken place via a transcultural curation ethos of Chinese contemporary art in recent decades – the frictions of which have amplified during pandemic times. This Special Issue of the Journal of Contemporary Chinese Art (JCCA) focuses on curatorial research and debates on the transcultural and the post-COVID world in China and beyond. The editorial sets out the key conceptual framework for assessing the significance of transcultural curation and Chinese contemporary art, both before and after the COVID-19 pandemic. The editorial unpacks key concepts and ideas such as transculturation as theory, method and practice; interrogates the processes and challenges of curating Chinese contemporary art in a transcultural context and the post-COVID world; and maps the issue content and structure. The Special Issue invocation to transcultural curation in a post-COVID world serves as a provocation to think carefully about the connections between past, present and future, and what continues and what is new for curatorial imaginaries.
La palabra «tregua» en Primo Levi: un neologismo arcaico
Authors: Scarpa Domenico
Published: December 2022

En su segundo libro, La tregua (1963), Primo Levi relata las peripecias de su regreso desde Auschwitz a Turín: un largo peregrinaje que duró ocho meses obligándole a cruzar Europa, y sobre todo Rusia, en todas direcciones. El artículo aborda los significados histórico, político, etimológico y psicológico de la palabra «tregua», las simetrías y contrastes dentro de la obra (además de algunas simetrías con la primera obra de Levi, Se questo è un uomo), su naturaleza de narración oral y algunas afinidades e intertextualidades con Heinrich Heine y François Rabelais.
Literatura del regreso. Presentación
Authors: Sanfilippo Marina
Published: December 2022

Este trabajo da unas claves generales sobre la sección monográfica dedicada a la literatura del regreso, mostrando cómo esta tiene un largo recorrido tanto en la oralidad como en la escritura y explicando las directrices que han marcado la selección de artículos.
La discapacidad de especial dificultad. Perspectivas y líneas de actuación
Authors: Carrillo Pujol Jordi
Published: December 2022

Al tratarse la discapacidad y el empleo en los estudios académicos, normalmente se hace de una forma conjunta, sin tener en cuenta la diversidad que existe dentro de este ámbito. La realidad es que, según el grado y la tipología de discapacidad, la incorporación al mercado laboral resulta más o menos sencilla. De hecho, la legislación española ha definido lo que denominamos discapacidad de “especial dificultad” con la finalidad de diferenciar unos grados y tipos determinados. Este artículo pretende incidir en las características de dicha categoría, mostrando aquellos aspectos que la diferencian del resto. Se proponen asimismo unas estratégicas líneas de acción a seguir por parte de la administración pública. Con la proposición de estas líneas de acción se pretende recibir una respuesta específica de apoyo a estas personas, cuya incorporación al mercado laboral no es tan solo un propósito loable y de responsabilidad social, sino que a su vez genera un impacto positivo en la economía, donde el empleo protegido va cada vez ganando mayor importancia.
Relationship between parental perceptions, family income and support received with family quality of life in families with a child with an intellectual disability
Authors: Ferrer Vidal Fina , Vilaseca Momplet Rosa , Bersabé Rosa María
Published: December 2022

Research has shown that families raising a child with intellectual disability (ID) face many challenges and need to implement adaptation strategies. Some authors suggest that positive parental perceptions and perceived control could reduce emotional impact and promote family wellbeing. Nevertheless, there are few studies about the relationship between parental perceptions and family quality of life (FQoL) in those families. In this study, we used data from a sample of 251 Spanish parents whose children have ID. Positive perceptions scale and control perceptions scale, Spanish FQoL scale under 18 years-old and a sociodemographic questionnaire were administered to those families. The results of bivariate analysis showed that some dimensions of positive perceptions were related to different areas of FQoL, for example, social inclusion and family accommodation. FQoL was associated with family income and support received. To predict the FQoL level, a multivariate linear regression analysis was conducted. Results indicated that FQoL scores can be predicted by a linear combination of positive perceptions and family income. Practical implications for promoting FQoL in these families are discussed.
Az idősebb munkavállalók munkavállalási szándékát meghatározó tényezők vizsgálata
Authors: Berde Éva , Drabancz Áron
Published: December 2022

A cikk az idősebb munkavállalók körében végzett kérdőíves felmérésünk eredményét mutatja be abból az aspektusból, hogy hogyan tervezi az idősebb korosztály későbbi életévei során munkaerőpiaci részvételét. A kérdőív közel 160-160 válaszadójának nagy része felmérésünk mindkét helyszínén – Székesfehérváron és vonzáskörzetében, valamint Budapesten – úgy nyilatkozott, hogy jelenlegi elképzelései szerint a jövőben is szeretne valamilyen formában dolgozni. Sokan nyugdíj mellett dolgoznának, de olyanok is szép számmal akadtak, akik a nyugdíjkorhatár betöltésekor nem kívánnak majd nyugdíjba vonulni. Felmérésünk jelezte, hogy a különböző áthidaló munkák, valamint az idősebbek igényeihez alkalmazkodó munkahelyek jól elősegíthetik az életkorban kitolódó munkavállalást, ami az idősödő magyar társadalomban egyre inkább elkerülhetetlen.
Teaching Entrepreneurship with Different Methodologies
Authors: Petheő Attila
Published: December 2022

The aim of the paper is to prove the usefulness of practice-oriented teaching methods in entrepreneurship skills and programs at Bachelor and Master level in the newly joined EU countries. The paper put this question in historical context, since entrepreneurship as a special form of firms is quite a new form in the Central-Eastern European countries. The historical legacy of these countries pushed the talented and agile workforce into the informal, irregular economy, which is the reason why the teachers and the lecturers were challenged after the change of the regime. This backwardness started to eliminate the obstacles and the barriers in front of the practice-oriented teaching methods.
SMA AS MEANS FOR SENSITIVE BIOMEDICAL SENSORS
Authors: Lindauer Vojtěch , Váňová Barbora , Rydlo Pavel
Published: December 2022

Shape memory alloys (SMA) are materials with specific electric, mechanic and thermal qualities originating in their microscopic structure and as such are used to design so-called Smart structures. In biomedicine, they are used mostly for their shape memory properties during intravasal surgery. The commonly used SMA material for biomedical purposes is Nitinol, a nickel-titanium alloy that exhibits, especially when annealed, among other properties also superelasticity and high resistivity with strain changes. This makes it suitable for usage in strain gauge sensors. In this work, NiTi annealed wires were used to create a strain gauge sensor, which exploits their unique properties. The properties of these sensors were then described using a climatic chamber, stretching device and a set of weights. Those properties were then compared to similar sensors, that are using different principles. The development, that followed, used these sensors in particular biomedical applications.
SOFTWARE TOOL FOR ANALYSIS OF VOXEL HUMAN BODY MODELS
Authors: Šmondrk Maroš , Babušiak Branko , Beňová Mariana , Janoušek Ladislav
Published: December 2022

The paper describes a software tool created to inspect the anatomical structures of any segmented voxel model of the human body for use in numerical analyses of the interaction of non-ionizing electromagnetic radiation with a metallic implant. A voxel model is a three-dimensional representation of the human body model in the form of a numerical array of indices that identify each element as belonging to a particular tissue, organ, or anatomical part. The process of virtual implant placement within these models while maintaining their anatomical limitations is complex and time-consuming. We have created a software tool in the MATLAB environment to simplify and speed up this process. As a representative case, we used the developed tool to identify three implantation sites of pacing electrodes within the cardiovascular system of the available AustinMan and AustinWoman models.
Vyznání víry (pokus o výklad)
Authors: Sokol Jan
Published: December 2022

Mnoho křesťanů si dnes láme hlavu s tím, jak „oslovit současného člověka“ – nejenom lidi neznámé a známé, ale třeba i vlastní dospívající děti. I když víme, že víru nedáváme my, nýbrž Kristus sám, je jistě na nás, abychom jí nekladli zbytečné překážky, nýbrž pomáhali. Protože křesťanské poselství trvá už dva tisíce let, vyžaduje to dnes jisté úsilí, nejenom nějakou „taktiku“ zvěstování, ale hlavně lepší pochopení u křesťanů samých. Křesťanská církev jako historický fakt a instituce se nemůže vzdát své minulosti, včetně těch vyjádření své naděje a víry, na nichž kdysi vznikla. Bible i tradiční texty jsou pro ni důležité nejen jako záruky její souvislosti a kontinuity, ale také proto, že ji stále kontrolují a korigují, kdykoli by pod vlivem dobové nálady a okolí na něco podstatného zapomněla, něco zanedbala.
The Recording, Reporting, and Use of School Attendance Data by School Personnel in The Netherlands: Toe the Line or Take a New Path?
Authors: Karel Evelyne , Heyne David , de Weerd Marga , Halberstadt Rene
Published: December 2022

Research signals the importance of promptly identifying and responding to emerging absenteeism, to prevent severe and chronic absenteeism. Prompt identification and response relies upon a good system for recording, reporting, and using data related to students’ school attendance and absence. The current article provides an overview of law, policy, and practice in the Netherlands regarding the recording, reporting, and use of school attendance data. We then consider the ways in which current law, policy, and practice help and hinder the work of school personnel as they endeavour to promote attendance and reduce absenteeism. Thereafter, we propose modifications to current policy and practice that could enhance the prompt identification and response to emerging absenteeism. When school personnel have easy access to reliable attendance data, and when they become accustomed to using the data to inform their work to promote attendance and respond to absenteeism, they are in a stronger position to support positive developmental outcomes among young people.
Teaching and learning using 21st century educational technology in accounting education: Evidence and conceptualisation of usage behaviour
Authors: Mat Dangi Mohamad Ridhuan , Mohamed Saat Maisarah , Saad Shukriah
Published: December 2022

Technologies are ubiquitous in the 21st century, and educators need to integrate relevant technologies into their teaching practices to meet stakeholders’ expectations and keep abreast with the accounting profession’s advancement. A mixed-method approach of quantitative and qualitative techniques was used in this study, with the latest version of the SPSS software (version 26) and NVivo software to analyse the data. The results depict the accounting educators’ usage efforts of 21st century educational technology tools and platforms; it is neither highly prevalent nor optimised. Future researchers could expand the investigation of 21st century educational technology by utilising the proposed constructs, model and hypotheses from this study’s qualitative findings. The study revives the stagnant educational technology literature in accounting education and explicates technology usage issues in accounting education, specifically in developing countries and the Asian region.
Implications for practice or policy:

Education ministries, higher education institutions, faculties, policymakers and academics should encourage educators to adopt and integrate 21st century educational technology into their practices.
The integration of 21st century educational technology in teaching and learning practice should align with individual attributes, technology characteristics and organisational factors.
Accounting educators must acquire technological competence through appropriate professional development and training programmes.
Introduction to the special issue “Higher education during and after COVID in Central and Eastern Europe”
Authors: Dunajeva Jekatyerina
Published: December 2022

Is there a need for more research on the effects of COVID-19 on education? While there is research suggesting that the impacts and “the troubling effects of the pandemic on research and higher education… might be felt for years to come” (The Lancet Editorial, 2020), there is also discernible pandemic fatigue, not only among the population, but researchers and subjects of research as well (Patel, Webster, Greenberg, Weston, & Brooks, 2020). Indeed, there has been an overabundance of published research articles in nearly all disciplines about the pandemic. The purpose of the current special issue is not to repetitively take stock of what happened during the pandemic but rather explore how the pandemic transformed the education system while rethinking certain practices and strategies engrained in the education system. To some extent, then, taking stock of what we know about the pandemic should help us prepare for the era some call the “new normal post-COVID-19 era” (Cahapay, 2020).
Research on the optimisation of the temperature field distribution of a multi microwave source agent system based on group consistency
Authors: Yang Biao , Wu Zhaogang , Gao Hao , Zhou Liexing , Sun Jun
Published: December 2022

Aiming at the problem of optimising the temperature field distribution of a multi microwave source agent system, in this work, group consistency is used to explore the multi microwave source agent collaborative tracking strategy to improve both the uniformity of the temperature distribution and the heating efficiency. First, to coordinate the inputting power state information of the multi microwave source agents, a consistency algorithm of non-fully connected communication topology is adopted. Second, according to the efficiency state information of the microwave source agents in different distribution positions of the cavity, the agent group consistency strategy and the group consistency strategy with expected power deviation are used to adjust the power distribution of each agent. Finally, the feasibility and effectiveness of the proposed strategy are verified by using heating materials with different specifications. The experimental results show that compared with the traditional multisource heating method the proposed temperature distribution optimization strategy based on group consistency can improve the temperature uniformity and heating efficiency.
Anaphoric reference in a German-Polish bilingual child
Authors: Jachimek Anna , Köpcke Klaus-Michael , Dimroth Christine
Published: December 2022

The study examines the use of referring expressions in anaphoric contexts in a German-Polish bilingual child between age 2;0 to 4;0. The longitudinal corpus consists of 160 video recordings of spontaneous speech in both languages. There are fundamental differences in the way anaphoric reference is expressed in German and Polish. Speakers of German refer to discourse-given referents either with a definite NP, a personal or a demonstrative pronoun. Speakers of Polish – a pro drop language without articles – mostly use bare nouns or null pronouns. Overt pronouns and demonstrative determiners are restricted to specific information structure conditions. We found an overuse of overt pronouns and demonstrative determiners in Polish in comparison to a monolingual Polish child of the same age and also qualitative differences in the use of the relevant expressions. Despite the fact that the earliest child grammar in both languages rather resembles the Polish target (no articles, no pronouns), the reliable markers of discourse-givenness encountered in the German input are rapidly acquired and overextended to Polish, before the more implicit Polish system is in place.
Effects of nano-ZrSi2 on thermal stability of phenolic resin and thermal reusability of quartz–phenolic composites
Authors: Ding Jie , Zhuang Yingluo , Shi Minxian , Huang Zhixiong , Qin Yan , Li Yan , Wang Cunku
Published: December 2022

In this article, nano-ZrSi2-modified phenolic (Ph) resin and nano-ZrSi2-modified quartz–phenolic (Q–Ph) composites are, respectively, prepared by resin casting and compression molding. The effect of nano-ZrSi2 on the thermal stability of Ph resin and the role of nano-ZrSi2 on the thermal reusability of Q–Ph composites are investigated by multiple thermal gravimetric analyses and mechanical tests. The strengthening mechanism of nano-ZrSi2 modification is investigated by the evolution of microstructure. The results show that the addition of nano-ZrSi2 enhances the thermal stability of Ph resin under repeated heating at 1,200°C in air. The enhancement in thermal stability of resin exhibits a positive effect on improving the thermal reusability of composites. Within the range of 20 repeated heating times, the flexural strength of nano-ZrSi2-modified composites is above 16.01 MPa, which is 163.8% higher than that of unmodified composites. The strengthening mechanism of nano-ZrSi2 is mainly in the inhibition of thermal oxidation and the reduction of microstructural defects during the repeated thermal environment.
Területfejlesztés és lakáspolitika vidéken az államszocializmus alatt
Authors: Szabó Árpád
Published: December 2022

A magyarországi államszocialista rendszer területfejlesztésének és lakáspolitikájának kutatása elsősorban az állami szubvenció által döntő mértékben támogatott nagyvárosi, új városi és lakótelepi fejlesztésekre koncentrál. A vidék, mint a fejlesztési forrásokból kimaradó, leszakadó terült jelenik meg. Jelen tanulmányban a magyarországi államszocialista éra területfejlesztésének és lakáspolitikájának vidéki aspektusait mutatom be. Ugyan a vidéki és városi területek közötti különbségek csökkentési szándéka a szocialista állampárt ideológiai kommunikációjában határozottan megjelent, a gyakorlatban a vidék-város dichotómia mindvégig erőteljes volt, ami abban is megnyilvánult, hogy az állampárt sajátos eszközökkel igyekezett megoldani a vidéki lakáshiányt. A tanulmány a korabeli fejlesztési koncepciók, rendeletek és jogszabályok szisztematikus elemzése segítségével arra a kérdésre keresi a választ, hogy a vidéki lakáspolitikai koncepciók hogyan alakították a vidéket.
The Spatiotemporal Neural Dynamics of Object Recognition for Natural Images and Line Drawings
Authors: Singer Johannes J.D. , Cichy Radoslaw M. , Hebart Martin N.
Published: December 2022

Drawings offer a simple and efficient way to communicate meaning. While line drawings capture only coarsely how objects look in reality, we still perceive them as resembling real-world objects. Previous work has shown that this perceived similarity is mirrored by shared neural representations for drawings and natural images, which suggests that similar mechanisms underlie the recognition of both. However, other work has proposed that representations of drawings and natural images become similar only after substantial processing has taken place, suggesting distinct mechanisms. To arbitrate between those alternatives, we measured brain responses resolved in space and time using fMRI and MEG, respectively, while human participants (female and male) viewed images of objects depicted as photographs, line drawings, or sketch-like drawings. Using multivariate decoding, we demonstrate that object category information emerged similarly fast and across overlapping regions in occipital, ventral-temporal, and posterior parietal cortex for all types of depiction, yet with smaller effects at higher levels of visual abstraction. In addition, cross-decoding between depiction types revealed strong generalization of object category information from early processing stages on. Finally, by combining fMRI and MEG data using representational similarity analysis, we found that visual information traversed similar processing stages for all types of depiction, yet with an overall stronger representation for photographs. Together, our results demonstrate broad commonalities in the neural dynamics of object recognition across types of depiction, thus providing clear evidence for shared neural mechanisms underlying recognition of natural object images and abstract drawings.

SIGNIFICANCE STATEMENTWhen we see a line drawing, we effortlessly recognize it as an object in the world despite its simple and abstract style. Here we asked to what extent this correspondence in perception is reflected in the brain. To answer this question, we measured how neural processing of objects depicted as photographs and line drawings with varying levels of detail (from natural images to abstract line drawings) evolves over space and time. We find broad commonalities in the spatiotemporal dynamics and the neural representations underlying the perception of photographs and even abstract drawings. These results indicate a shared basic mechanism supporting recognition of drawings and natural images.
Fighting antibiotic resistance—strategies and (pre)clinical developments to find new antibacterials
Authors: Walesch Sebastian , Birkelbach Joy , Jézéquel Gwenaëlle , Haeckl F P Jake , Hegemann Julian D , Hesterkamp Thomas , Hirsch Anna K H , Hammann Peter , Müller Rolf
Published: December 2022

Antibacterial resistance is one of the greatest threats to human health. The development of new therapeutics against bacterial pathogens has slowed drastically since the approvals of the first antibiotics in the early and mid‐20th century. Most of the currently investigated drug leads are modifications of approved antibacterials, many of which are derived from natural products. In this review, we highlight the challenges, advancements and current standing of the clinical and preclinical antibacterial research pipeline. Additionally, we present novel strategies for rejuvenating the discovery process and advocate for renewed and enthusiastic investment in the antibacterial discovery pipeline.
Production of Single Cell Protein from Banana Peel Waste in Batch Fermentation Using Saccharomyces Cerevisiae
Authors: Azwar Azwar , Mukhlishien Mukhlishien , Muslim Abrar , Hadissa Putri , Ningsih Utari Hadi , Zanil M. F. , Ali J. M.
Published: December 2022

Through engineering the fermentation process, it is hoped that new data can be obtained that will explain the ability of Saccharomyces cerevisiae to maximize the production of single-cell protein (SCP). SCP microorganisms have a high protein content, making them suitable for use as a human protein source as well as food additives in the cattle and fishing industries. The goal of this experiment is to see if the microbe Saccharomyces cerevisiae can generate SCP from banana peel waste. Some of the process variables used in this study include the variation in nutrition, fermentation time, and the effect of pH variations on SCP production. Where the variation in pH used is 3; 3.5; 4; 4.5; 5; and 5.5. As for the nutrients used, namely (NH4)2SO4 and KH2PO4 with a variety of nutrients, namely 0; 0.3; 0.6; 0.9; and 1.2 grams. Then the fermentation time was varied to 1,2,3,4 days. This study also analyzed the growth of microorganism cells using wet weight and dry weight with variations in pH and nutrition. The variation in nutrition is the same as the variation in the previous analysis of protein content, and the fermentation time is 1,2,3,4,5,6, and 7. In the analysis of protein content with Kjeldahl protein, the obtained optimal pH is 4.5 and the optimal protein content is 0.6 grams. As for the fermentation time, the optimal protein content is obtained on the 4th day. For the growth of microorganisms, the optimal pH is obtained at a pH value of 4.5 with optimal nutrition of 0.6 grams, and the optimal fermentation time is obtained on the 7th day.
Influence of Surface Resistance of Silicon p-i-n Photodiodes n+-Layer on their Electrical Parameters
Authors: Kukurudziak M.S.
Published: December 2022

Silicon quadrant p-i-n photodiodes of different concentrations of diffused phosphorus in the n+- layer were fabricated. The experimental curve of phosphorus impurity distribution along the depth of the diffusion layer is obtained. The influence of charge carrier concentration in this layer on the dark currents of responsive elements and the guard ring was studied. Volt-ampere characteristics of photodiodes were measured. It was seen that when the surface resistance of the n+-layer decreases, the dark currents decrease, the samples with a surface resistance of 1,9 – 2,4 Ohm / □ have approximately the same level of dark currents of responsive areas, i.e. further increase in charge carrier concentration makes no change. As to dark currents of photodiode guard rings, it was found that for the most part they depend on the state of the crystal periphery but not on the level of doping. The influence of the surface resistance of the n+-layer on  interconnection resistance between the responsive areas and the protective ring, and no influence on the capacitance of the photodiodes were revealed.
Repertorios de prácticas en la política turca hacia el conflicto de Libia y la intervención militar de 2020
Authors: Casani Alfonso , Fernández-Molina Irene
Published: December 2022

Este artículo estudia la interacción del gobierno de Turquía con los distintos actores libios que han proliferado en el país desde los levantamientos antiautoritarios de 2011, atendiendo al repertorio de prácticas desplegado por Turquía entre 2011 y 2021. Para ello, analiza tres episodios contenciosos, correspondientes al estallido de la guerra civil en 2011, en 2014-2015, y la reanudación del conflicto en 2019-2020. El artículo identifica una intensificación del papel de Turquía en el conflicto libio, cuyo repertorio de prácticas oscila entre la colaboración y rivalidad en un “juego de suma cero” entre actores libios enfrentados en un proceso de guerra civil.
Static and dynamic properties of sisal fiber polyester composites – Effect of interlaminar fiber orientation
Authors: Senthilkumar Krishnasamy , Siva Irulappasamy , Sultan Mohamed Thariq Hameed , Rajini Nagarajan , Siengchin Suchart , Jawaid Mohamad , Hamdan Ahmad
Published: December 2022

The effect of fiber orientation was studied relative to the static and dynamic properties of sisal/polyester composites. Different composites were developed using the compression moulding technique with the aid of a specially designed mould. Composite laminates were formulated by stacking a number of fiber lamina with different orientations such as 90º/0º /90º, 0º /90º /0º, 90º /0º /0º /90º, 0º /45º /0º, 0º /90º /45º /45º /90º /0º, and 0º /45º /90º /90º /45º /0º. In general, the performance of static and dynamic characteristics was found to be significantly influenced by the effect of interlaminar fiber orientation. Experimental results exhibited a higher flexural strength of 68 MPa and an impact strength of 320 J/m in the case of 0º /90º /45º /45º /90º /0º oriented composites. Dynamic characteristics such as natural frequency and damping were found to be higher in the case of 0º /45º /0º and 0º /90º /0º, respectively. Morphological analysis was performed for understanding the interlaminar orientation and failure mechanisms between the fiber and the matrix.
Consumer attitudes toward preference and use of wood, woodenware, and furniture: A sample from Kayseri, Turkey
Authors: Guzel Tugba Andac
Published: December 2022

Wood, as a natural and sustainable source, has many fields of utilization. It is crucial for people to use wood in housing in ways that reflect their preferences and attitudes. The focus of this study is to measure consumers’ thoughts, knowledge, and awareness of wood materials. A survey was conducted about how consumers’ knowledge and conscious attitudes are reflected in their purchase and use of various wooden domestic items, including wood furniture and woodenware. Survey data were analyzed using descriptive statistics and one-way ANOVA. The results indicated that individuals believe that wood is a natural and organic (45.6%) material that people enjoy and become happy (43.7%) when using it. ‘Furniture’ (82.5%) is the most frequent way of utilizing wood for individuals at home. However, these people tend to use wood composite furniture, which offers more functionality and design options (71.8%), as natural wood is an expensive material (57.8%).
Study the stability of chickpea endophytic actinobacteria species on broth and agar culture media
Authors: Sapkota Sita Ram , Prasad Paneru Tarani
Published: December 2022

The actinobacteria acts by colonising plant roots and increases the nitrogen fixation capacity of the rhizobial partner. In this study, endophytic actinobacterial strains CP21A2, CP56, CP84B, and CP200B isolated from chickpea were evaluated for the sporulation rate in solid and liquid media. These resultant spores were evaluated for their stability at different pH and temperature. Calcium carbonate in the liquid broth and MS medium in solid agar media can be used to increase the sporulation rate of the actinobacteria. Additionally, we found out that almost all spore-producing strains were stable at 70°C 4 minutes but temperatures greater than that were lethal to the spores obtained from both types of media. In addition, the tested spore strains were more sensitive and prone to lysis at alkaline pH rather than acidic. Furthermore, our study suggested that CP56 spores obtained from liquid media and CP84B from solid media can be the best performers in promoting the overall growth of plants and nodules. However, further detailed investigations need to be carried out in order to determine their influence on the growth and development of legume plants which can be useful to increase the yield in the agricultural industry.
Modelling of space antenna deployment using open source software
Authors:   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Khoroshylov S.V. , Shamakhanov V.K. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Martyniuk S.E. ,   EOS Ukraine, Sushko O.Y. ,   EOS Ukraine
Published: December 2022

The goal of this article is to develop a dynamic model of a space antenna with the pantograph structure and to study the processes of its deployment using open-source software. Methods of theoretical mechanics, multibody dynamics, computational mechanics, and computer modeling were used in the research. A mesh antenna of the novel design, which is recommended for mini-satellites, is considered as the object for modeling. The most significant difference between this antenna and others is the design of the support ring in the form of a pantograph. To develop a model of the space antenna dynamics and implement it using open-source software, some simplifications were made due to the complexity of the structure. The antenna model is represented as a system of rigid and flexible bodies connected by hinges. Carbon fiber rods are modeled with the help of a flexible finite element using the method of absolute nodal coordinates, which allows one to model large deformations of the structure. Aluminum hinge assemblies are modeled as several rotation joints connected by conventional rigid elements. The main modeled properties of these hinge assemblies are the stiffness, location, and direction of the axes of rotation of the hinges. The tension forces created by the stretched mesh are modeled using springs. The cable drive of the antenna deployment mechanism is modeled as a load acting on the corresponding elements in defined local positions. An algorithm for building a model of the space antenna to simulate the reflector deployment process in the HotInt open-source software is presented. Using the built model, antenna deployment simulations are carried out for different cases, which differ in the forces used for the deployment. Values of deployment time, variations of angles between the V-folded bars, and tensions in the diagonal rods of the antenna sections during the antenna deployment are obtained. The approach proposed in the article can be implemented using free software, ensures flexibility of modeling, and reduces the model development time.
Forced vibrations of a three-layered double-curved shell with an elastic honeycomb core
Authors:   A. Pidgorny Institute of Mechanical Engineering Problems of the National Academy of Sciences of Ukraine, Avramov K.V. , Uspensky B.V. ,   A. Pidgorny Institute of Mechanical Engineering Problems of the National Academy of Sciences of Ukraine
Published: December 2022

This paper presents a mathematical model of vibrations of a three-layered double-curved shell under geometrically nonlinear deformation. The middle layer is a honeycomb manufactured using FDM additive technologies. The mechanical properties of the honeycomb were assessed by a homogenization procedure. The outer layers of the shell are thin, and they are made of carbon-filled plastic. The model is based on a higher-order shear theory and accounts for the orthotropy of the mechanical properties of all the shell layers. Each layer of the shell is described by five variables (three displacement projections and two rotation angles of the normal to the middle surface). The properties of linear vibrations were studied using discretization by the Rayleigh?Ritz method. Because the middle layer of the shell is far lighter and more compliant in comparison with the outer layers, the computational process has some features. The eigenferquencies and eigenmodes of the shell were found for a further analysis of nonlinear vibrations. The mathematical model of forced vibrations of the shell under geometrically nonlinear deformation is a system of nonlinear ordinary differential equations derived by the assumed-mode method. Nonlinear periodic vibrations and their bifurcations were studied using a numerical procedure, which is a combination of the continuation method and the shooting technique. The properties of the nonlinear periodic vibrations and their bifurcations in the regions of fundamental and subharmonic resonances were studied numerically. A spherical panel and a hyperbolic paraboloid panel were considered. It was shown that when a disturbing force is applied at a point out of the panel’s center of gravity, the panel’s eigenmodes interact, and the frequency response and the bifurcation diagram change qualitatively in comparison with the case where that force is applied at the panel’s center of gravity. An agreement between the results was studied as a function of the number of terms in the Rayleigh-Ritz and assumed-mode expansions.
Congenital Hypothyroidism: Screening and Management
Authors: Rose Susan R. , Wassner Ari J. , Wintergerst Kupper A. , Yayah-Jones Nana-Hawa , Hopkin Robert J. , Chuang Janet , Smith Jessica R. , Abell Katherine , LaFranchi Stephen H. ,   SECTION ON ENDOCRINOLOGY EXECUTIVE COMMITTEE, Wintergerst Kupper A. , Bethin Kathleen E. , Bruggeman Brittany , Brodsky Jill L. , Jelley David H. , Marshall Bess A. , Mastrandrea Lucy D. , Lynch Jane L. ,   COUNCIL ON GENETICS EXECUTIVE COMMITTEE, Burke Leah W. , Geleske Timothy A. , Holm Ingrid A. , Introne Wendy J. , Jones Kelly , Lyons Michael J. , Monteil Danielle C. , Pritchard Amanda B. , Smith Trapane Pamela Lyn , Vergano Samantha A. , Weaver Kathryn , Alexander Aimee A. , C4unniff Christopher , Null Mary E. , Parisi Melissa A. , Ralson Steven J , Scott Joan , Spire Paul
Published: December 2022

Untreated congenital hypothyroidism (CH) leads to intellectual disabilities. Newborn screening (NBS) for CH should be performed in all infants. Prompt diagnosis by NBS leading to early and adequate treatment results in grossly normal neurocognitive outcomes in adulthood. However, NBS for hypothyroidism is not yet practiced in all countries globally. Seventy percent of neonates worldwide do not undergo NBS.

The recommended initial treatment of CH is levothyroxine, 10 to 15 mcg/kg daily. The goals of treatment are to maintain consistent euthyroidism with normal thyroid-stimulating hormone and with free thyroxine in the upper half of the age-specific reference range during the first 3 years of life. Controversy remains regarding the detection of thyroid dysfunction and optimal management of special populations, including preterm or low-birth-weight infants and infants with transient or mild CH, trisomy 21, or central hypothyroidism.

NBS alone is not sufficient to prevent adverse outcomes from CH in a pediatric population. In addition to NBS, the management of CH requires timely confirmation of the diagnosis, accurate interpretation of thyroid function testing, effective treatment, and consistent follow-up. Physicians need to consider hypothyroidism in the face of clinical symptoms, even if NBS thyroid test results are normal. When clinical symptoms and signs of hypothyroidism are present (such as large posterior fontanelle, large tongue, umbilical hernia, prolonged jaundice, constipation, lethargy, and/or hypothermia), measurement of serum thyroid-stimulating hormone and free thyroxine is indicated, regardless of NBS results.
Polypharmacy in Older People with Heart Failure: Roles of the Geriatrician and Pharmacist
Authors: Stefil Maria , Dixon Matthew , Bahar Jameela , Saied Schabnam , Mashida Knievel , Heron Olivia , Shantsila Eduard , Walker Lauren , Akpan Asangaedem , Lip Gregory YH , Sankaranarayanan Rajiv
Published: December 2022

Heart failure (HF) is a common health condition that typically affects older adults. Many people with HF are cared for on an inpatient basis, by non-cardiologists, such as acute medical physicians, geriatricians and other physicians. Treatment options for HF are ever increasing, and adherence to guidelines for prognostic therapy contributes to polypharmacy, which is very familiar to clinicians who care for older people. This article explores the recent trials in both HF with reduced ejection fraction and HF with preserved ejection fraction and the limitations of international guidance in their management with respect to older people. In addition, this article discusses the challenge of managing polypharmacy in those with advanced age, and the importance of involving a geriatrician and pharmacist in the HF multidisciplinary team to provide a holistic and person-centred approach to optimisation of HF therapies.
Rancang Bangun Sistem Pendaftaran Pelatihan Berbasis Web
Authors: Fauzi Ahmad
Published: December 2022

Penyerapan angkatan kerja di sektor formal yang tidak maksimal mendorong pemerintah mengedepankan pada pendidikan berbasis keahlian. Pendidikan vokasi maupun lembaga pelatihan menjadi salah satu sarana untuk meningkatkan keahlian dari tenaga kerja. Upaya ini dilakukan untuk menigkatkan kemampuan tenaga kerja dan juga mempersiapkan angkatan kerja baru untuk dapat berkarir di sektor formal. Tujuan dari penelitian ini yaitu membangun sistem pendaftaran pelatihan berbasis web yang mana dapat memudahkan pihak penyelenggara pelatihan untuk mengelola pelatihan dan calon peserta pelatihan untuk mendaftar pelatihan. Hasil pengujian aplikasi menunjukkan sistem dapat berjalan baik pada perambah yang diujikan meskipun terdapat kemungkinan bugs sebesar 0.08 dan defects sebesar 0.28.