bluuebunny/crossref_metadata_2025 huggingface dataset:
Menimbang Ulang Apokalips Kitab Daniel
Authors: Karman Yongky
Published: November 2020

Abstrak: Pembacaan atas aspek apokaliptik Kitab Daniel sering dipusatkan pada bagian kedua kitab itu (Dan. 7-12). Bagian pertamanya (Dan. 1-6) hanya dibaca sebagai cerita-cerita heroisme iman. Dengan begitu, sifat apokaliptik tidak kelihatan sebagai karakteristik kitab itu secara keseluruhan. Apokaliptik sendiri cenderung dikaitkan dengan eskatologi, dan bagian kedua kitab tersebut secara mencolok memakai kata “akhir.” Pengaitan aspek apokaliptik dengan fatalisme akhir zaman berkembang di kalangan sekte kiamat. Kendati aspek eskatologisnya, apokaliptik seharusnya juga dipahami dalam matriks hikmat. Jika dibaca dalam kesatuan dan keutuhannya, kitab itu memperlihatkan gagasan mengenai hidup berhikmat dalam mengantisipasi kiamat, bukan dengan menarik diri dari dunia, melainkan setia kepada Allah dan kritis terhadap arogansi kekuasaan.

 

Kata-kata Kunci: apokaliptik, kiamat, radikal, Makabe, sektarian, nubuat, hikmat, eskatologi.

 

Abstract: The reading of the apocalyptic aspect of the Book of Daniel is often focused on the book’s second part (Dan. 7-12). Its first part (Dan. 1-6) is read only as stories of faithful heroism. In this manner, the apocalyptic dimension is not seen as characteristic of the book as a whole. Apocalypse itself tends to be associated with eschatology, and indeed the second part of the book strikingly makes use of the word “end.” The association of apocalypse with the fatalism of the end time develops within the doomsday sect. Despite its eschatological dimension, the apocalyptic aspect should be read within the matrix of wisdom. When being read in its unity and integrity, the book demonstrates the idea of living wisely in the anticipation of the end, not by withdrawing oneself away from the world, but by being faithful to God and being critical of the arrogance of power.

 

Keywords: apocalyptic, doomsday, radical, Maccabees, sectarian, prophecy, wisdom, eschatology.
PERANAN IMUNOSTIMULAN AKAR KUNING Arcangelisia flava Merr PADA GAMBARAN AKTIVASI SISTEM IMUN IKAN MAS (Cyprinus carpio L)
Authors: Maryani Maryani , Rosdiana Rosdiana
Published: November 2020

Salah satu cara untuk meningkatkan kualitas benih dari ikan budidaya adalah dengan meningkatkatkan respon imun sehingga kebal terhadap serangan penyakit. Penelitian ini bertujuan untuk meningkatkan respon imun non spesifik dari ikan mas dengan pemberian dosis optimum ekstrak Akar Kuning. Perlakuan yang diberikan adalah perbedaan dosis ekstrak Arcangelisia flava Merr., dimana perbedaan dosis tersebut adalah sebagai berikut : A = dosis 0 gr/kg pakan, B = dosis 2,5 gr/kg pakan, C = dosis 5,0 gr/kg pakan, D = dosis 7,5 gr/kg pakan, dan E =  dosis 10,0 gr/kg pakan.  Parameter utama yang diamati adalah pemeriksaan jumlah Hb, He, total eritrosit, total leukosit, persentase neutrofil, monosit, limfosit, dan tingkat kelangsungan hidup (SR).  Pengambilan darah selama penelitian, dilakukan sebanyak dua kali,yaitu pengambilan darah yang pertama dilakukan pada hari ke-14 setelah diberi ekstrak akar kuning, dan pengambilan darah kedua pada hari ke-30 setelah diberi ekstrak akar kuning dan diinfeksi bakteri A.hydrophila.  Hasil penelitian menunjukkan bahwa penggunaan Arcangelisia  flava Merr. sebagai imunostimulan mempengaruhi jumlah Hb, He, total eritrosit, total leukosit, persentase neutrofil, monosit, limfosit dan tingkat kelangsungan hidup Cyprinus carpio L yang terinfeksi oleh Aeromonas hydropila.
PENERAPAN UNDERGRAVEL AIRLIFT PUMP PADA AKUAKULTUR IKAN NILA (Oreochromis Sp)
Authors: Nur Kurniawan M. , Halil Halil , Wicaksono Driyanto Wahyu
Published: November 2020

Undergravel airlift pump is a simple filter system that uses air. The purpose of this study was to analyze the efficiency of using Undergravel Airlift Pump in Aquaculture Oreochromis sp. The approach used is an experimental approach with 2 treatments and 1 control. Analysis of the data used is the analysis of variance (ANOVA). The results showed that the application of undergravel airlift pump had an impact on water quality. The treatment of middle airlift  position is more effective compared to the bottom airlift  and control. The temperature and pH parameters were not significantly different; dissolved oxygen and total dissolved solid were significantly different.
PENGGUNAAN EKSTRAK AKAR TUBA (Derris elliptica) DENGAN DOSIS YANG BERBEDA DALAM PENGANGKUTAN IKAN PATIN SISTEM TERTUTUP
Authors: Monica Dini Puspa , Syaifudin Mochamad , Dwinanti Sefti Heza
Published: November 2020

The transportation process can lead to stress which increases mortality in fish. Efforts to reduce mortality in the process of fish transportation can be conducted by minimizing the metabolic activities of fish during transportation. One of the natural substances that is used for fish transportation is tuba roots. The aim of this study is to determine the effect of different dosages of tuba root extract on the transport of catfish seeds with a closed transport system for 12 hours. This research was conducted at the Aquaculture Laboratory, Aquaculture Study Program, Faculty of Agriculture, Sriwijaya University. The research was conducted in April 2019. This study used a completely randomized design (CRD) method with four different dosage treatments (T) and three replications. The dosages of tuba root extract were: 0 ml.L-1 (T0), 0.05 ml.L-1 (T1), 0.10 ml.L-1 (T2), 0.15 ml.L-1 (T3). The parameters observed were blood glucose levels, water quality, survival of catfish after transportation and maintenance for 7 days. The results showed that T1 (0,05 ml.L-1) was gave the highest survival rate of 91.66±2.88%, with the lowest stress level indicated by blood glucose values 89±30.63. In addition, there was no further effect from the administration of tubal root extracts to protect the life of the fish after transportation and maintenance.Keywords : Tuba root, catfish, transportation
DAYA TETAS TELUR IKAN PATIN (Pangasius hypophthalmus) PADA pH MEDIA BERBEDA
Authors: Putra Prily Lovian , Jubaedah Dade , Syaifudin Mochamad
Published: November 2020

The pH of waters is one of external factors that is important for succesfull of hatching percentage of fish eggs. The pH stimulates the chorionase enzyme become more active that can softens the egg chorion. The aim of this study was to determine the optimum pH value for hatching of catfish eggs. This research has been conducted in Fisheries Basic Laboratory, Department of Aquaculture, Department of Fisheries, Agriculture Faculty, Universitas Sriwijaya from August 31st to September 16th, 2019. The research metehod used Completely Randomized Design with five treatments and 3 replications. The treatments are P1 (pH of 5±0.2), P2 (pH of 6±0.2), P3 (pH of 7±0.2), P4 (pH of 8±0.2) dan P5 (pH of 9±0.2). The results showed that different value of water pH gave significant effect on hatching percentage, hatching time and survival rate of catfish larvae but did not significant effect on percentage of abnormal larva. The highest hatching percentage (80.33 %) was in treatment of pH 7 ± 0.2 (P3), the fastest hatching percentage (21.59 hours) was in treatment of pH 8 ± 0.2 (P4), the highest survival rate of catfish larvae (99.44 %)  was in treatment of pH 7 ± 0.2 (P3) and the highest percentage of abnormal larvae (2.22 %) was in treatment pH 5 ± 0.2 (P1). During the research, water quality were in tolerance range for hatching and rearing of eggs and larvae catfish i.e. temperature of 26.2 – 27.9 oC, dissolved oxygen of 4.7 – 5.5 mg.l-1, and ammonia of 0.22 – 0.47 mg.l-1.Keyword : Hatching eggs, catfish, pH value
ANALISA ASPEK REPRODUKSI IKAN TOMAN (Channa micropeltes) DI SUNGAI BELIDA KABUPATEN MUARA ENIM
Authors: Yonarta Danang , Yulisman Yulisman , Riswandi Riswandi
Published: November 2020

Management of snakehead fish resources in swamp waters need to be done to anticipate a decline in stock in the waters. At this time the area where snakehead fish still have an abundant population is in southern sumatera, precisely in the Belida River, Muara Enim Regency. Until now there has been no information regarding the reproductive aspects of snakehead fish, their location and spawning season. The purpose of this study was to obtain information about the reproductive aspect of snakehead fish which includes sex ratio, gonad maturity level. Gonad maturity index and egg fecundity. The research was conducted in September-December 2019. The location was determined based on the natural conditions of the Belida River and human activities. Fish sampels were caught using experimental gill nets with ½ mash net size. Sampling of fish is done every 4 months with a time interval of once a month. The resuls of study in the male and female fish ratio 1,6:1. This ratio consisted of 109 fish (62,3%) and 66 female fish (37,7%). Gonadal maturity indeks  for male snakehead fish ranged from 0,21 to 0,86, while female snakehead fish ranged from 1,18 to 2,30. snakehead fish egg fecundity were 24.786 eggs with a diameter of 2,20 – 2,51
Wianek i rysy. Sprawa Marianny Dolińskiej
Authors: Herczyńska Sara
Published: November 2020

Artykuł dotyczy fotografii potocznie nazywanej „wianuszkiem z dzieci” i przedstawiającej czwórkę martwych dzieci powieszonych na drzewie. Zdjęcie pochodzi z 1923 roku i przedstawia zabite przez matkę dzieci Marianny Dolińskiej. W latach 90. fotografia zaczęła szeroko funkcjonować jako ilustracja rzezi wołyńskiej i zbrodni dokonywanych przez UPA na Polakach, pojawiała się na okładkach książek i stała się modelem dla pomnika. Widoczne na fotografii rysy zostały zinterpretowane jako drut kolczasty. Autorka podejmuje próbę interpretacji fotografii i jej losów jako symptomu wyparcia kobiecej przemocy.
Wreaths and Creases. The Case of Marianna Dolińska
Authors: Herczyńska Sara
Published: November 2020

The article concerns the photography commonly called “garland of children” (wianuszek z dzieci) and depicting four dead children hanged on a tree. The photo is from 1923 and shows the children of Marianna Dolińska killed by the mother. In the 1990s, this photography began to function extensively as an illustration of the Volhynia massacre and crimes committed by the Ukrainian Insurgent Army against Poles, appeared on book covers, and became a model for a monument. The scratches present in the photograph have been interpreted as barbed wire. The author attempts to interpret the photography and its history as a symptom of repression of female violence.
“Splendid Deformities”. An Emancipatory Critique of Cultural Homogeneity in Sin-ying Ho’s Deformed Ceramics
Authors: Burchmore Alex
Published: November 2020

This paper identifies an aesthetic of deformation in contemporary porcelain sculptures by Hong Kong-born, New York-based artist Sin-ying Ho. A selection of these are discussed with reference to three historic case-studies in ceramic deformity: wares that have been malformed when fired due to negligence, lack of vigilance, or misfortune; wares that have transformed in the kiln due to allegedly mysterious powers; and the eighteenth-century fashion for chinoiserie as a style of the monstrous, deformed and obscene. With reference to these case studies, it is argued that Sin-ying Ho’s ceramic sculptures represent deformity as something to be celebrated, endorsing an emancipatory narrative of diversity and open-minded tolerance.
The Colour of History
Authors: Szerszeń Tomasz
Published: November 2020

Does History have its own colour? And what about the colour of the disaster? Where does it meet with a reflection on photography? This essay combines considerations on the use of colours in Boris Mikhailov’s photography and their historiosophical role in reflection on the decline of the Soviet Union and the years of transformation, with the question about “Chernobyl effect” in Soviet and post-Soviet society, especially in the context of political visibility/invisibility of radiation.
Visual Lessons
Authors: Burska Bogna , Morra Joanne , Pijarski Krzysztof , Smith Marquard , Sokołowska Joanna , Szcześniak Magda
Published: November 2020

A transcript of the discussion "Image Lessons. Visual Pedagogies in Troubled Times", which took place at the Institute of Polish Culture, University of Warsaw on December 18, 2018.
TOXICITY AND HAZARD OF ZOLMITRIPTAN (EXPERIMENTAL STUDY)
Authors: Bidevkina M. V. , Golubeva M. I. , Bobrineva I. A. , Limantsev A. V. , Potapova T. N. , Razumnaya I. N. , Savchenko A. Yu. , Ramenskaya G. V.
Published: November 2020

Zolmitriptan is a widely used antimigraine drug, belongs to the group of second-generation tryptans, has a pronounced central mechanism of action and high selectivity to serotonin receptors of 5HT1D- and 5HT1B-types. Zolmitriptan belongs to hazard class 3 according to GOST 12.1.007-76: DL50 are 660 (495 - 881) mg/kg for male mice and 1045 (749 - 1292) mg/kg for female mice when administered into the stomach. When injected into the abdominal cavity, DL50 is 172 (131 - 225) mg/kg for male mice. The drug has a weak irritating effect on the mucous membranes of the eyes, does not irritate the skin, there are no signs of skin-resorptive action, and has a low ability to accumulate. The threshold of acute inhalation action is set at 0,9 mg/m3 for the effect on the functional state of the nervous system and liver. For the zolmitriptan aerosol, it is recommended to approve the tentative safe exposure level in the air of the working area at 0,01 mg/m3 and the tentative safe exposure level in the atmospheric air of urban and rural settlements at 0,0001 mg/m3.
INFORMATION ON THE IMPLEMENTATION OF THE EAEU TR «ON THE SAFETY OF CHEMICAL PRODUCTS» DATED 03.03.2017 № TR EAEU 041/2017 IN THE RUSSIAN FEDERATION
Authors: H. Hamidulina H.
Published: November 2020

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Why Not Say It Straight? On the Pragmatics of Indirect Speech in Coptic
Authors: Uljas Sami
Published: November 2020

Indirect speech with full adjustment of person deixis in Coptic is shown to occur exclusively in contexts where the report is not based on an original assertive speech act or when the reporter (i.e. the real speaker) considers its propositional content invalid or unacceptable. As opposed to the much commoner direct speech, indirect speech thus seems to have represented a pragmatically charged and modally marked strategy of reporting at this stage of the Egyptian language.
On the binary classification problem in discriminant analysis using linear programming methods
Authors: Olusola Michael O. , Onyeagu Sydney I.
Published: November 2020

This paper is centred on a binary classification problem in which it is desired to assign a new object with multivariate features to one of two distinct populations as based on historical sets of samples from two populations. A linear discriminant analysis framework has been proposed, called the minimised sum of deviations by proportion (MSDP) to model the binary classification problem. In the MSDP formulation, the sum of the proportion of exterior deviations is minimised subject to the group separation constraints, the normalisation constraint, the upper bound constraints on proportions of exterior deviations and the sign unrestriction vis-à-vis the non-negativity constraints. The two-phase method in linear programming is adopted as a solution technique to generate the discriminant function. The decision rule on group-membership prediction is constructed using the apparent error rate. The performance of the MSDP has been compared with some existing linear discriminant models using a previously published dataset on road casualties. The MSDP model was more promising and well suited for the imbalanced dataset on road casualties.
ASSESSMENT OF BIOMECHANICAL PARAMETERS OF LOCOMOTION IN PATIENTS WITH ORTHOPEDIC AND NEUROLOGICAL PROFILE IN A CLINICAL SANATORIUM
Authors: Ponomarenko Уи. N. , Lukyanenko V. N. , Bogdanova L. А. , Lepekhina N. V.
Published: November 2020

In the article there are analyzed the biomechanical indicators that make it possible to objectively evaluate the whole set of pathological parameters of locomotion, develop an individual program of rehabilitation measures, which can significantly increase the effectiveness of treatment at the sanatorium-resort stage.
VIOLATIONS OF VISUAL-SPATIAL REPRESENTATIONS IN CHILDREN WITH INFANTILE CEREBRAL PALSY, APPROACHES TO CORRECTIVE THERAPY
Authors: Komardina S. M. , Vlasenko S. V.
Published: November 2020

The article notes that the issues of rehabilitation of patients with infantile cerebral palsy are an urgent and extremely difficult problem. In conditions of deficiency of cerebral supply due to organic lesions, functional pathological foci are formed in various brain structures in patients of this group. In such cases, the neuropsychological research method makes it possible to more accurately diagnose and lateralize the primary disorders of mental processes, to highlight the structure of the defect. The purpose of this report is to analyze the correctional work in violation of visual-gnostic functions in patients with various forms of cerebral palsy. A correction program was developed individually for each child, purposefully stimulating the parieto-occipital parts of the cerebral cortex. The increase in the child's motor abilities in combination with the improvement of visual-spatial representations made it possible to significantly increase the effectiveness of the entire rehabilitation program
Phenolic compounds of Tagetes lucida Cav. with antibacterial effect due to membrane
damage
Authors:   Autonomous University of
            Coahuila, Villa-Silva Perla Y. , Iliná Anna ,   Autonomous University of
            Coahuila, Ascacio-Valdés Juan A. ,   Autonomous University of
            Coahuila, Esparza-González Sandra C. ,   Autonomous University of
            Coahuila, Cobos-Puc Luis Enrique ,   Autonomous University of
            Coahuila, Rodríguez-Herrera Raúl ,   Autonomous University of
            Coahuila, Silva-Belmares Sonia Y. ,   Autonomous University of
            Coahuila
Published: November 2020

Tagetes lucida Cav. (Asteraceae=Compositae) is used for treating stomach
infections. The study focused on evaluating the composition and antimicrobial effect of
an extract of T. lucida Cav. The plant extracted with ethanol at 10% w/v, and the
extract composition analyzed by Rp-HPLC-MS. The antibacterial effect was evaluated
against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella
choleraesuis using disk diffusion, microdilution and bioautography methods. The sytox
and comet assays were used to evaluate the mechanism of action. In this way, nine
phenolic compounds were detected in the extract of T. lucida. The extract exhibited
activity only on S. aureus (MIC of 4.000 mg/ml). The bioautography revealed that the
phenolic compounds could act synergistically. The sytox and comet tests showed an
antibacterial action of the extract on the bacterial membrane and DNA of this bacterial
strain.
Impact of Kuntai Capsules on LIF, IGF-1 and EGF expression in the implantation
window of endometrium in mice
Authors:   Zhengzhou
            University, Tan Li , Li Xiao-Xu ,   Traditional Chinese Medical
            Hospital of Zhengzhou, Chu Xi-Ying ,   Zhengzhou
            University, Li Yan ,   Zhengzhou
            University, Wan Li-Jing ,   Zhengzhou
            University
Published: November 2020

To investigate the influence of Kuntai capsules on the expression level of
leukemia inhibitory factor (LIF), insulin-like growth factor-I (IGF-1) and epidermal
growth factor (EGF) during the mouse’s implantation window of superovulation period and
controlled ovarian hyperstimulation period. 90 female mice were randomly divided into
six groups in control, superovulation and controlled ovarian hyperstimulation (COH)
conditions. The RNA expression of EGF, LIF and IGF-1 in the endometrium on the 4th day
of pregnancy was detected, and the relative expression was compared. mRNA expression of
these three factors in endometrium was significantly lower in superovulation and COH
groups than control group (p<0.001) . mRNA expression of these three factors in
endometrium remained obviously lower in superovulation plus kuntai capsule group and COH
plus kuntai capsule group than control group (p<0.01). mRNA expression of these three
factors in endometrium was lower in control group than in the NS plus kuntai capsule
group (p<0.05). Kuntai capsule cannot completely reverse the endometrial damages
caused by superovulation and COH. Thus Kuntai capsule could partially improve a mouse’s
endometrial receptivity during the implantation window.
CURRENT UNDERSTANDING OF THE MOLECULAR MECHANISMS IN ONCOGENESIS OF GASTROINTESTINAL STROMAL TUMORS
Authors: Gvaldin Dmitriy , Omelchuk Yekaterina , Timoshkina Natalya , Trifanov Vladimir , Sidorenko Yuriy
Published: November 2020

The association of genetic driver changes in gastrointestinal stromal tumors (GIST) with clinical implications is the most studied aspect in all solid tumors. Genotyping of particular exons c-KIT and PDGFRA included in the standard practice of diagnosis and treatment of GIST. The review analyzes the current understanding of the molecular-genetic mechanisms and markers that underlie the GIST profiling. Of particular interest are wild-type tumors of c-KIT and PDGFRA, in which activating mutations of the RAS, BRAF and EGFR oncogenes are found, associated with the early stages of disease progression. The data of studies of genetic and epigenetic changes in GIST, which revealed the prognostic value of inactivation of CDKN2A and p53, deletions of 22q, 1p and 15q, CpG hypermethylation are presented. New factors that determine a high risk of progression of GISTs are described: inactivation of dystrophin, DNA hypomethylation, increased expression of miRNAs and HOTAIR. The progress achieved in understanding the molecular mechanisms of GISTs give the opportunity of developing and effectively applying new therapeutic approaches, expanding the range of molecular genetic markers that determine patient surveillance.
CRYOGENIC TECHNOLOGY IN MINIMALLY INVASIVE TREATMENT OF BREAST CANCER. LITERATURE REVIEW
Authors: Belyaev Aleksey , Prokhorov Georgiy , Zakharova Viktoriya
Published: November 2020

The survey of literature includes period from the first attempts of palliative cryodestruction to modern miniinvasive technologies with the use of different methods of navigation and control. Material, that shows scientific validity, efficiency, positive technologic and clinical evolution of method, is collected sufficiently. But despite of general positive and optimistic assessment of cryogenic technologies’ opportunity, there are no results of randomized studies comparing distant results of cryogenic and existing standard treatment of breast cancer. In conclusion authors indicate the objective difficulties in problem’s studying and offer possible resolutions.
EXTRAMURAL VENOUS INVASION AS A FACTOR OF DISTANT METASTASIS IN PATIENTS WITH LOCALLY ADVANCED RECTAL CANCER
Authors: Polynovskiy Andrey , Kuzmichev Dmitriy , Mamedli Zaman , Suraeva Yu. , Madyarov Zhasur , Aniskin A.
Published: November 2020

Aim: In this article extramural venous invasion (EMVI) in patients with locally advanced rectal cancer (LARC) is evaluated as a risk factor of distant metastasis. Materials and methods: This study is based on experience made in proctological department of N.N. Blokhin National Medical Research Center of Oncology. Retrospective analysis was performed on a group of 230 patients with LARC with stage mrT3(CRM+)/T4N0-2M0. All patients underwent long course of chemoradiotherapy with capecetabine, then 2-4 courses of chemotherapy CapOx were conducted in induction and/or consolidation scheme. Results: There were no critical differences in the effect of EMVI (+) on the development of reccurences in comparison with the EMVI (-) group (p>0.05). Along with that EMVI(+) patients were significantly associated with distant metastasis (43 patients - 27,4%) then in EMVI(-) group (2 - 2,74%) (p<0,05). The positive mr-EMVI result was more likely to be present in patients with T4 then in T3 group (p<0,05). A positive EMVI status was 81,4% in patients with the III stage, which is significant higher than in patients with II stage - 55,7% (p<0,05). 3-year recurrent-free survival of patients with EMVI(+) was 64%, compared with the group of patients with EMVI (-) - 93%, which was a significant difference (HR 0.03; 95% CI, 0.08-0.19 p<0.001). Conclusion: The definition of extramural vascular invasion indicates a poor prognosis and could be used for treatment planning of neoadjuvant chemoradiation and adjuvant chemotherapy.
SPECT-CT IMAGING AND SENTINEL LYMPH NODES BIOPSY IN PATIENTS WITH CERVICAL CANCER
Authors: Bisyarin M. , Krzhivitskiy Pavel , Kanaev Sergey , Novikov Sergey , Berlev I. , Mikaya Nikolay , Artemeva Anna , Kargopolova Margarita
Published: November 2020

Purpose: to determine accuracy of sentinel lymph node biopsy in patients with IAB-IIAB cervical cancer. Materials and methods: diagnostic performance of sentinel lymph node (SLN) biopsy was evaluated in 46 women with cervical cancer. SLN mapping was performed after peritumoural injection of 99mTc-labelled radiocolloids. All regional lymph nodes with uptake of radiocolloids were regarded as sentinel. SSLN biopsy was completed by standard lymph node dissection in all cases Results: SLN were visualized and detected in 42 of 46 (91.3%) cases. The monolateral pattern of lymph flow was determined in 19 women, bilateral localization of SLN revealed in remained 23 cases. Monolateral lymph flow characterized by high probability of metatstic involvement of regional lymph nodes (21.1%) and low sensitivity of SLN biopsy (0%). On the contrary, in women with bilateral lymph flow metastases in regional lymph nodes were mentioned in 2 of 23 cases (8.7%) and sensitivity of SLN biopsy was 100%. Conclusion: In patients with SLN localization on both sides of the pelvis SLN biopsy correctly predicted status of regional lymph nodes. In cases with monolateral localization of SLN biopsy characterized by high false negative rates.
REHABILITATION OF PATIENTS WITH PROSTATE CANCER
Authors: Kasparov Boris , Semiglazova Tatyana , Kovlen Denis , Ponomarenko Gennadiy , Klyuge Valeriya , Krutov Anton , Osetnik Vladislav , Tynkasova M. , Kondrateva Kristina , Zaozerskiy O. , Semiglazov Vladislav , Nosov A. , Belyaev Aleksey
Published: November 2020

The purpose of rehabilitation for prostate cancer patients is to recover psychological, physical, cognitive, social, and vocational functions. Prostate cancer treatment options have the risk of several side effects including loss of muscle strength, fatigue, pain, urinary incontinence, erectile dysfunction, cognitive problems, decrease in bone density, weight loss, gynecomastia, and hot flushes with stress-related psychosocial problems. This paper describes briefly cancer rehabilitation of patients with prostate cancer for minimizing the morbidity rate associated with prostate cancer treatment and to improve QOL.
VOICE RESTORATION IN PATIENTS WITH ORAL CAVITY AND OROPHARYNGEAL CANCERS USING INNOVATIVE TECHNOLOGIES
Authors: Balatskaya Lidiya , Choynzonov Yevgeniy , Krasavina Yelena , Kostyuchenko Yevgeniy , Novokhrestova Darya
Published: November 2020

Currently, voice restoration in patients with oral cavity and oropharyngeal cancers after organ-preserving and reconstructive surgeries is relevant and socially significant. Materials and methods. From 2014 to 2019, a total of 110 patients with oral cavity and oropharyngeal cancers (Tj 3N0 2M0) were treated at the Department of Head and Neck Tumors of Cancer Research Institute. Organ-preserving surgeries with a flap reconstruction following hemiglossectomy or glossectomy with horizontal plane resection of the mandible, and hemiglossectomy or glossectomy with resection of the mandibular and muscles of the floor of the mouth were performed. In the postoperative period, violation of speech, swallowing and chewing processes were observed. After removal of the nasophageal probe and sutures, all patients underwent speech rehabilitation to restore speech function using innovative technologies. Together with scientists from Tomsk University of Control Systems and Radioelectronics, we have developed and introduced into clinical practice OnkoSpeech v1.0 software package that allows us to apply a personalized approach to planning speech rehabilitation based on a sound spectrum spectral analysis for patients with oral cavity and oropharyngeal cancers after organ-preserving surgery. Results. The software package allows us to evaluate the quality of speech and work with a database of records of speech therapy sessions. A positive result of voice restoration was observed in all 110 patients in the period from 18 to 30 days. We have received objective confirmation of the assumption that in most cases after the rehabilitation, the acoustic characteristics approach the speech indices in comparison with the preoperative period. Conclusion. Our technique makes it possible to increase the effectiveness of the restoration of speech function, reduce the time of speech rehabilitation, and significantly increase the social status and quality of life of cancer patients.
RESULTS OF COMBINED MODALITY TREATMENT WITH PREOPERATIVE CHEMOTHERAPY IN ESOPHAGEAL CANCER PATIENTS
Authors: Dobrodeev Aleksey , Afanasev Sergey , Urmonov Umidzhon , Avgustinovich Aleksandra , Frolova Irina , Cheremisina Olga , Tarasova A.
Published: November 2020

The purpose of the study: to analyze the efficacy of combined modality treatment including preoperative chemotherapy with gemcitabine/cisplatin in patients with stage II-III esophageal cancer (EC). Materials and methods: The study included 70 patients with stage II-III EC, who were treated at the Cancer Research Institute (Tomsk, Russia) from 2012 to 2019. The patients were divided into 2 groups. Group I comprised 35 patients, who received 2 cycles of preoperative chemotherapy with gem-citabine (1250 mg/m2 on days 1 and 8) and cisplatin (80 mg/ m2 on day 1) followed by radical surgery. Group II included 35 patients who underwent surgery alone. All patients underwent subtotal resection of the esophagus with simultaneous esophageal reconstruction using gastric tube (68.6%) or colon tissue (31.4%). Results: The overall tumor response to preoperative chemotherapy according to RECIST 1.1 criteria was 57.1%, including complete response (5.7%) and partial response (51.4%). No severe complications were observed. R0 resection was achieved in all patients (100%). No difference in the rate of postoperative complications between Group I and Group II was found (34.3% and 40%, respectively). There was no statistically significant difference in the mortality rate between treatment groups (8.6% versus 57%) (p>0.05). Pathological complete tumor response was 5.7%. In Group I patients, the 2-year disease-free and overall survival rates were 71.8% and 81.3%, respectively. The corresponding values in Group II patients were 39.4% and 51.5%, respectively (p=0.01). Conclusion: Preoperative chemotherapy for patients with stage II-III EC demonstrated high response rates, having no adverse effect on the perioperative period and mortality. The 2-year survival rates were significantly higher in patients, who received combined modality treatment with preoperative chemotherapy than in patients, who underwent surgery alone.
EXPERIENCE OF SENTINEL LYMPH NODE BIOPSY AFTER NEOADJUVANT CHEMOTHERAPY
Authors: Semiglazov Vladimir , Zhiltsova E. , Krivorotko Petr , Kanaev S. , Trufanova E. , Krzhivitskiy P. , Komyakhov Aleksandr , Tabagua T. , Nikolaev K. , Bessonov A. , Ivanov V. , Gigolaeva Larisa , Ivanova O. , Zernov K. , Dashyan G. , Paltuev R. , Semiglazov V. , Emelyanov A. , Busko E. , Chernaya A. , Artemyeva A. , Nonikov S.
Published: November 2020

Objective: to evaluate the diagnostic accuracy of sentinel lymph node biopsy after neoadjuvant chemotherapy. Materials and methods: the study included 264 patients with early (operable) and locally advanced breast cancer (cT1N1-3, cT2N0-3, cT3N0-3, cT4N0-3). All patient underwent corebiopsy with histological examination and ICH (to determine the tumor grade (G), expression of ER, PR, Ki67, Her2), fine needle aspiration of suspicious axillary lymph nodes. Before, during and after the neoadjuvant therapy, all patients undergo: physical examination (palpation), mammography, ultrasound, SPECT-CT. The effect of neoadjuvant chemotherapy was evaluated after the 2nd, 4th, and 6th cycles of therapy. 197 patients (74.6%) had tumors more than 2 cm (cT2), 210 (79.8%) were N + (cN1-N3), 174 patients (65.9%) had luminal tumors (ER+), 84 patients (31.8%) had triple-negative breast cancer (ER-, PR-, HER2-) and 53 patients (20%) had HER2-positive breast cancer. Most patients (56.4%) had a high level (> 30%) of Ki67 expression. Results: 210 of 263 patients (79.8%) had metastases in regional lymph nodes before treatment. Almost half of them had a decrease in the stage from N + to ycN0 after NACT. According to the ultrasound data 48 patients had decreasing of the stage to ycN0. Sentinel lymph node biopsy showed ypN0 category in 35 patients and ypN+ in 13 patients. The false-negative rate was 5.7%. The sensitivity of the method was 94.3%, the accuracy of ultrasound was 95.8%. According to the SPET-CT data 51 patients had decreasing of the stage to ycN0. Sentinel lymph node biopsy showed ypN0 category in 35 patients and ypN+ in 16 patients. The false-negative rate was 2.85%. The sensitivity of SLNB after NACT in patients cN0/cN+ → ycN0 was 91.2%, accuracy - 96.3%, predictive value of the negative result - 92.4%. Conclusion: SLNB can be performed in cN0/cN+ → ycN0 patients after NACT, provided that 3 or more sentinel lymph nodes are removed and there are no tumor cells in them.
CLINICAL AND MORPHOLOGICAL CASE OF SALIVARY GLAND ADENOCARCINOMA WITH THE DEVELOPMENT OF GENERALIZED METASTASES
Authors: Vorobeva Olga , Lastochkin Aleksey
Published: November 2020

Tumors of the salivary glands make up about 2-6% of all human tumors. There is a certain dependence of the frequency of metastasis on the variants of histological types of neoplasms. Low-differentiated (48.9% of neoplasms) and moderately differentiated (20.7% of cases) forms of malignant tumors are more prone to metastasis. In this clinical and morphological case, a variant of low-grade adenocarcinoma of the parotid salivary gland with generalized hematogenous metastases to the internal organs is described. The histological description determines areas of tumor tissue with indistinct signs of functional differentiation, consisting of polymorphic low-differentiated cells that form incorrectly formed glandular structures and complexes with hyperchromic nuclei. Against the background of tumor progression, multiple organ failure occurred.
THE DYNAMIC OF ANGIOGENESIS FACTORS IN C57BL/6-PLAUTMI.IBUG-THIS PLAU6FDHU/GFDHU MICE AT CHRONIC NEUROGENIC PAIN AND GROWTH OF THE MELANOMA
Authors: Kit Oleg , Frantsiyants Yelena , Kaplieva Irina , Surikova Yekaterina , Neskubina Irina , Bandovkina Valeriya , Trepitaki Lidiya , Cheryarina Natalya , Nemashkalova Lyudmila , Sidorenko Yuriy
Published: November 2020

Tumor vascularisation is an important aspect of melanoma growth. The system of urokinase and its receptor (uPA/uPAR system) plays an important role in tumor metastasis which makes it an attractive therapeutic target. Our purpose was to study the dynamics of angiogenic growth factors in male and female uPA gene-knockout mice (C57BL/6-PlautmI.IBug-This Plau6FDhu/GFDhu strain) during the growth of experimental B16/F10 melanoma developing in animals with chronic neurogenic pain (CNP). Material and methods. Group 1 included С57BL/6 mice of both genders, n=75; group 2 - C57BL/6-Plautm1.1Bug-This PlauGFDhu/GFDhu mice (uPA gene knockout), n=46. Levels of VEGF-A, VEGF-C, sVEGF-R1, and sVEGF-R3 were determined by ELISA (CUSABIO BIOTECH Co.,Ltd., China). Results. uPA gene-knockout mice of both genders with melanoma and CNP showed survival similar to animals with a normal genome; however, the period to tumor onset was longer in such animals (by 2.6 times on average), and the volume of primary tumors was on average 2.2 times higher. The concentration of angiogenesis factors in skin and tumor samples was lower in male and female uPA gene-knockout mice with experimental B16/F10 melanoma and CNP, compared to animals without the knockout. Conclusions. uPA gene knockout inhibits VEGF in males, unlike females, and chronic neurogenic pain stimulates the formation of this factor in knockout animals of both genders which confirms triggering of urokinase-independent pathway of angiogenesis activation under the influence of CNP.
Vitamino D stoka gali didinti astmos tikimybę
Authors: Tamašauskienė Laura , Šitkauskienė Brigita
Published: November 2020

Pastaruoju metu mokslo literatūroje aprašomas vitamino D vaidmuo įvairių ligų patogenezėje. Plačiai tyrinėjama vitamino D įtaka ir astmai. Tyrimai rodo, kad pacientų, sergančių astma, kraujyje nustatoma mažesnė vitamino D koncentracija nei sveikiems žmonėms. Manoma, kad vitaminas D didina imuninės sistemos komponentų, kurie pasižymi uždegimą slopinančiomis savybėmis, kiekį. Keliama hipotezė, kad vitamino D vartojimas sergant astma galėtų turėti teigiamos įtakos šios ligos eigai. Straipsnio tikslas - apžvelgti vitamino D savybes bei jo įtaką astmai.
Preliminary Reviews Of The Late Medieval Historical Geography Of Jizzakh (On The Basis Of Written Sources And Archaeological Data)
Authors:   Associate Professor Of The Department Of History And Teaching Methods Candidate Of Historical Science Jizzakh State Pedagogical Institute, Uzbekistan, Hasanovich Pardaev Ahrorqul
Published: November 2020

The article examines the historical medieval towns, fortresses and other geographical areas of the Jizzakh oasis based on written sources and data obtained from archeological excavations. As a result of scientific analysis, the geographical locations of the Jizzakh Horde and its environs, which are the location of the modern city of Jizzakh in the late Middle Ages, have been clarified.
Location- and object-based attention enhance number estimation
Authors: Pomè Antonella , Thompson Diego , Burr David Charles , Halberda Justin
Published: November 2020

Humans and non-humans can extract an estimate of the number of items in a collection very rapidly, raising the question of whether attention is necessary for this process. Visual attention operates in various modes, showing selectivity both to spatial location and to objects. Here, we tested whether each form of attention can enhance number estimation, by measuring whether presenting a visual cue to increase attentional engagement will lead to a more accurate and precise representation of number, both when attention is directed to location and when it is directed to objects. Results revealed that enumeration of a collection of dots in the location previously cued led to faster, more precise, and more accurate judgments than enumeration in un-cued locations, and a similar benefit was seen when the cue and collection appeared on the same object. This work shows that like many other perceptual tasks, numerical estimation may be enhanced by the spread of active attention inside a pre-cued object.
АUGMENTED REALITY TECHNOLOGIES [АR] AND COLLAGES AS WAYS OF ORGANIZING RUSSIAN LANGUAGE TEACHING
Authors: Хамраева Е.А.
Published: November 2020

В статье рассматривается реализация новых технологических приемов в методике преподавания русского языка – использование графического коллажа как средства организации дополненной реальности. Статья посвящена также описанию применения технологии дополненной реальности в языковом обучении, что позволяет образовательным организациям перейти с традиционных методик на интерактивные, особенно важные в ситуации вынужденного дистанционного обучения. Автор делает вывод о том, что дополненная реальность в РКИ – это система, создаваемая с помощью цифровых средств с целью эмоционального воздействия, путем использования «дополненных» элементов в процессе обучения, а особенно онлайн-обучения. Коллажирование при этом – разновидность технологического приема, позволяющего эмоционально вовлечь обучаемого в материал, вызвать желание познавать новое.

The article considers the implementation of new technological techniques in the teaching of the Russian language – the use of graphic collage as a means of organizing augmented reality. The article also describes the use of augmented reality technology in language learning, which allows educational organizations to switch from traditional methods to interactive ones, which are especially important in the situation of forced distance learning. The author concludes that augmented reality in Russian as Foreign Language is a system created using digital means for the purpose of emotional impact, by using "augmented" elements in the learning process, and especially online learning. At the same time, collaging is a kind of technological technique that allows you to emotionally involve the learner in the material, to cause a desire to learn new things.
Determinants of Stunting Events in Children Aged 6-23 Months in Locus and Non-Locus Areas in East Luwu Regency
Authors: Parenreng Kanaang Mabe , Hadju Veni , Bahar Burhanuddin , Jafar Nurhaedar , Hidayanty Healthy , Saleh Lalu Muhammad
Published: November 2020

Nationally, the prevalence of stunting in children under five in Indonesia is 30.8%. The incidence of stunting varies from region to region. This study aims to determine the determinants of stunting in children aged 6-23 months in the locus and non-loci in East Luwu Regency. This research is an observational analytic study using a cross sectional design. The study population was 858 children aged 6-23 months in five locus villages and five non-locus villages. A sample of 200 people was taken using purposive sampling method, data were analyzed using the chi square test and logistic regression using the SPSS application. The results showed the similarity in terms of parental education in both regions. In general, the father has a job and the mother is a housekeeper. Income levels are higher in locus areas. As much as 43.1% of baduta had stunting at locus area and 22.4% at non locus. The logistic regression test showed that the factors associated with stunting in the locus were family members smoking (p = 0.032), hand washing practices (p = 0.036) and exclusive breastfeeding (p = 0.001). Meanwhile, non-locus areas were a history of diarrhea disease (p = 0.049) and hand washing practices (p = 0.052). Combined analysis of locus and non-loci showed that family members smoking (p = 0.005), exclusive breastfeeding (p = 0.001), frequency of complementary feeding (p = 0.027) and hand washing practices (p = 0.001) were determinants of stunting. The most dominant variable in the locus was exclusive breastfeeding, while non-locus was a history of diarrhea. Conclusion: The determinants of locus stunting are family members smoking, hand washing practices and exclusive breastfeeding. Meanwhile, non-locus areas are a history of diarrhea disease and hand washing practices.
Evaluation of Electric Energy Losses in Kirkuk Distribution Electric System Area
Authors: Mustafa Sameer , Yasen Mohammed , Abdullah Hussein
Published: November 2020

Correct calculations of losses are important for several reasons. There are two basic methods that can be used to calculate technical energy losses, a method based on subtraction of metered energy purchased and metered energy sold to customers and a method based on modeling losses in individual components of the system.
For considering the technical loss in distribution system included: transmission line losses, power transformer losses, distribution line losses and low-voltage transformer losses. This work presents an evaluation of the power losses in Kirkuk electric distribution system area and submit proposals and appropriate solutions and suggestions to reduce the losses. A program under Visual Basic was designed to calculate and evaluate electrical energy losses in electrical power systems.
Weakest Bus Identification Based on Modal Analysis and Singular Value Decomposition Techniques
Authors: Jalboub M. K. , Rajamani H. S. , Abd-Alhameed R.A. , Ihbal A. M.
Published: November 2020

Voltage instability problems in power system is an important issue that should be taken into consideration during the planning and operation stages of modern power system networks. The system operators always need to know when and where the voltage stability problem can occur in order to apply suitable action to avoid unexpected results. In this paper, a study has been conducted to identify the weakest bus in the power system based on multi-variable control, modal analysis, and Singular Value Decomposition (SVD) techniques for both static and dynamic voltage stability analysis. A typical IEEE 3-machine, 9-bus test power system is used to validate these techniques, for which the test results are presented and discussed.
Using Water Energy for Electrical Energy Conservation by Building of Micro hydroelectric Generators on The Water Pipelines That Depend on The Difference in Elevation
Authors: Gatte Mohammed , Kadhim Rasim , Rasheed Farhan
Published: November 2020

In this research we study the elevations of cities and the water resources specially at the dams reservoirs and the distance between them(dams & cities), we use the Google Earth program to determine these elevations and calculate the difference between the average level (elevation) of water at the dam and the average level of cities, which we want to supply it by water, in order to save electrical power by using the energy of supplied water through pipe line from dams to the cities, the pressure of supplied water must be calculated from the difference in elevations(head). The saving of energy can be achieved by two ways. The first is the energy saving by reduce the consumed power in the pumping water from river, which is used for different purposes. The second is the hydroelectric power generated by establishing a micro hydroelectric generator on the pipe line of the water supplied.
A Performance Study of Wireless Broadband Access (WiMAX)
Authors: Al-Adwany Maan
Published: November 2020

WiMAX (worldwide interoperability for microwave access) is one of the wireless broadband access technologies which supplies broadband services to clients, but it surpasses other technologies by its coverage area, where one base station can cover a small city. In this paper, WiMAX technology is studied by exploring its basic concepts, applications, and advantages / disadvantages. Also a MATLAB simulator is used to verify the operation of the WiMAX system under various channel impairments and for variety of modulation schemes. From the simulation results, we found that WiMAX system works well in both AWGN and multipath fading channels, but under certain constraints that are addressed in this paper.