bluuebunny/crossref_metadata_2025 huggingface dataset:
An Epigenetic Manifestation of Alzheimer's Disease: DNA Methylation
Authors: Feng Boyi , Zheng Junli , Cai Ying , Han Yaguang , Han Yanhua , Wu Jiaqi , Feng Jun , Zheng Kai
Published: June 2024

Alzheimer's disease (AD), the most common form of dementia, has a complex pathogenesis. The number of AD patients has increased in recent years due to population aging, while a trend toward a younger age of onset has arisen, imposing a substantial burden on society and families, and garnering extensive attention. DNA methylation has recently been revealed to play an important role in AD onset and progression. DNA methylation is a critical mechanism regulating gene expression, and alterations in this mechanism dysregulate gene expression and disrupt important pathways, including oxidative stress responses, inflammatory reactions, and protein degradation processes, eventually resulting in disease. Studies have revealed widespread changes in AD patients' DNA methylation in the peripheral blood and brain tissues, affecting multiple signaling pathways and severely impacting neuronal cell and synaptic functions. This review summarizes the role of DNA methylation in the pathogenesis of AD, aiming to provide a theoretical basis for its early prevention and treatment.
Correlates of Control Preferences, Participation in Decision-making and Activation in Patients with Substance Use Disorder
Authors: Serrano-Pérez Pedro , Rivero-Santana Amado , Daigre-Blanco Constanza , Palma-Álvarez Raúl Felipe , Nistal-Franco Icía , Ramos-Quiroga Josep Antoni , Grau-López Lara
Published: June 2024

Background: Treatment of Substance Use Disorder (SUD) is complex and therefore including patients in the therapeutic process is needed. Patient-Centered Care (PCC) and Shared Decision-Making (SDM) have been associated with greater satisfaction, self-control, and less substance use. However, correlates of SDM have not been investigated in this population.
Method: A cross-sectional analysis was carried out in 214 SUD patients to identify sociodemographic, clinical and psychological correlates of preferences and perceptions about participation in SDM and degree of activation. The Control Preference Scale (CPS), the Shared Decision-Making Questionnaire (SDM-9-Q) and the Patient Activation Measure (PAM) were used to assess the PCC elements. Multinomial logistic regression was used to analyze the correlates of the CPS variables (preferred role, perceived role, and role matching). For SDM-9-Q and PAM, multilevel linear regression was used.
Results: Preferring an active role, compared to a shared one, was significantly associated with higher educational level, lower neuroticism, absence of affective and alcohol use disorders, and higher quality of life. Perceiving greater participation was significantly associated with not being a new patient, having fewer legal problems, higher severity of alcohol consumption, not presenting polydrug use and main substance use different than opioids or sedatives. Activation was associated with higher scores in the personality trait activity, a preference for an active role and greater perception of being involved in the decision process.
Conclusions: Patients with milder clinical profiles prefer an active role compared to a shared one. Patients who prefer or perceive a shared or passive role did not show relevant differences. Greater activation was related to preference for an active role and the perception of having been involved in decisions.
Investigation and Analysis of Emotional State and Oxytocin Level in Patients with Postpartum Depression
Authors: Yu Xue , Zhang Weiping , Gao Yan
Published: June 2024

Background: Postpartum depression (PPD) is a common mental disorder in postpartum women, negatively impacting physical and mental health. Correlation analysis can predict the relationship between variables. By detecting the abnormal level of oxytocin, clinicians can timely know the emotional states of parturients to guide clinical practice. This study aimed to investigate the relationship between emotional states and oxytocin (OT) levels in patients with PPD.
Materials and Methods: The medical records of 166 PPD patients admitted to Cangzhou Central Hospital from May 2020 to March 2023 were retrospectively analyzed. After excluding 9 patients who did not meet the inclusion criteria, the remaining 157 patients were included in this study. The 7-item Generalized Anxiety Disorder Scale and Patient Health Questionaire-9 items were used to evaluate the emotional states of 157 patients, and the included subjects were grouped according to the results of the scale. The serum OT levels of patients was measured, and the relationship between the OT levels and emotional states was analyzed.
Results: In this study, 75 patients were included in the mild anxiety group, and 82 patients were included in the moderate and severe anxiety group. Seventy-nine patients were selected as the mild depression group, and 78 patients were included in the moderate and severe depression group. The mild anxiety group had a higher OT level than the moderate and severe anxiety group (Z = –10.121, p < 0.001). The mild depression group had a higher OT level than the moderate and severe depression group (Z = –9.758, p < 0.001). OT level was negatively correlated with anxiety and depression scores (r = –0.676, r = –0.665, p < 0.001).
Conclusion: There is a specific relationship between the emotional states of PPD patients and the OT levels in the body, and active clinical management strategies need to be implemented.
Effect of Symptom Levels of Children's Food Allergy on Maternal Depression: A Cross-sectional and Cohort Study
Authors: Zhang Jian , Xie Meiyan , Liao Xiaoqing , Zhang Yang , Chen He
Published: June 2024

Background: Maternal depression may have negative impacts on children's behavior and mental health. Childhood food allergy is a common health issue, yet its relationship with maternal depression remains incompletely understood. This study aimed to analyze the association between children's food allergy symptoms and maternal depression through cross-sectional and cohort studies.
Methods: This study selected a total of 580 children with food allergy and their mothers who met the inclusion criteria in Ganzhou Women and Children's Health Care Hospital from April 2015 to April 2022, evaluated the symptom levels of children's food allergy according to the guidelines, assessed the depressive symptoms of mothers using self-rating depression scale (SDS), and analyzed the relationship between the symptom severity of children's food allergy and the risk of maternal depression; at the same time, one-year follow-up of mothers without depression was carried out to measure the incidence of depression to further explore this relationship.
Results: The 580 children with food allergies in the cross-sectional study consisted of 365 (62.93%) males and 215 (37.07%) females, aged (8.98 ± 2.30) years, with 298 (51.37%) experiencing Level-Ⅰ, and 282 (48.63%) experiencing Level-Ⅱ. A total of 56 (9.66%) mothers suffered from depression, aged (42.74 ± 5.42) years. Adjusting for confounders including mother's age, education level, marital status, family income, comorbidities, history of allergies, family history of food allergies, history of psychiatric disorders, current smoking status, current alcohol consumption, current regular exercise status, childhood food allergens and food allergy categorization, the mothers of children with child food allergy symptom Level-Ⅱ were found to have a higher risk of depression compared with mothers with child food allergy symptom Level-Ⅰ, odds ratio (OR) = 2.025 (95% confidence interval (CI): 1.319–3.128, p = 0.001). In the one-year cohort study, 38 (7.25%) mothers had new-onset depressive symptoms. Mothers of children with a child food allergy symptom Level-Ⅱ had an OR = 2.165 (95% CI: 1.612–2.902, p < 0.001) for depressive symptoms compared to mothers with a child food allergy symptom Level-Ⅰ.
Conclusion: Among children with food allergy symptom scores of Level-Ⅰ and Level-Ⅱ, higher levels were associated with a higher prevalence of depression in their mothers.
3R Nursing Combined with Dietary and Nutritional Interventions Enhances Self-care Ability in Elderly Patients with Vascular Dementia
Authors: Wang Jian , Du Binghui
Published: June 2024

Background: Vascular dementia (VD) is an extremely common neurological dysfunction in the elderly population, and greatly affects the patient's ability to take care of themselves. Recent research suggests that VD patients need more targeted and individualized nursing during treatment, so as to enhance cognitive function and therapeutic efficacy. The objective of this study is to observe the effect of reminiscence, reality, and remotivation (3R) nursing combined with dietary and nutritional interventions on elderly patients with VD, so as to provide clinical evidence for the management of VD in older adults.
Methods: 120 elderly VD patients admitted between December 2022 and December 2023 were selected, including 64 cases receiving 3R nursing combined with dietary and nutritional interventions (the research group) and 56 cases receiving routine nursing (the control group). The two groups were compared in terms of neurological function, self-care ability, and nutritional status before and after nursing, as well as nursing compliance. After the completion of the care, patients' quality of life and family satisfaction were investigated.
Results: In comparison with the control group, the research group displayed higher scores on the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), greater self-care ability, and higher levels of nutritional proteins and grip strength (p < 0.05). In addition, patients in the research group displayed greater nursing compliance and quality of life of patients, as well as higher family satisfaction (p < 0.05).
Conclusions: 3R nursing combined with dietary and nutritional interventions can effectively improve the neurological function of VD patients and enhance their self-care ability.
Targeting kidney cell senescence: a new paradigm for the treatment of chronic kidney disease?
Authors: Garibotto Giacomo , Esposito Pasquale , Picciotto Daniela , Verzola Daniela , Costigliolo Francesca , Zanetti Valentina , Saio Michela , Russo Elisa , Viazzi Francesca
Published: June 2024

Cellular senescence is a condition where cells undergo a permanent cell cycle arrest, accompanied by a unique set of functional and morphological changes. While initial studies of senescence have largely focused on its role as a barrier to extended cell division and tumorigenesis, in recent years cell senescence has emerged as an important driver of aging and age-related disease in different tissues, including the kidney. Accelerated cell senescence may decrease kidney repair capacity because of cell cycle arrest; in addition cell senescence promotes glomerulosclerosis and tubulointerstitial fibrosis via the production and release of proinflammatory and matrix-degrading molecules. Although almost all glomerular and tubular cells may undergo senescent changes, the glomerular podocytes and proximal tubule cells are the most commonly affected cells. In these days, treating cell senescence is moving his steps from the preclinical to the clinical stage. While cell senescence appears to be well accepted as a new mechanism for kidney damage and chronic kidney disease [CKD] progression, there still are many unanswered questions regarding how to dectect it in kidney biopsies, which is prognostic meaning of individual kidney senescnce markers, which the role of different cells involved, as well as the efficacy of the emerging senescence-targeted therapies on the progression and complications of CKD.
Customer Relationship Management: An Evaluation of Critical Success Factors in Lebanon Firms
Authors:   , Saber David A.
Published: June 2024

CRM stands for Customer Relationship Management. It is used to know more about customers' needs and behaviors in order to build up stronger relationships with them. In the end, good customer relationships are the heart of business success. There are many technological components to CRM, but thinking about CRM in mainly technological terms is a mistake. Managing a successful CRM implementation requires an integrated and balanced approach to people, process, and technology. Also it is the organizational change and cultural shift that businesses need to do, in order to actually deliver good customer service and distinguish themselves from their competitors in the market place. This paper will examine critical factors for successful CRM implementation generally and in the Lebanese context more specifically. These factors will be identified from in-depth interviews with managers in Lebanese companies that implemented CRM or are in the process of implementing it.
The Impact of Lebanese Customers' Perception on their Banks' New Product Development Process
Authors:   , Tchobanian Lisa Yeghia
Published: June 2024

This research was conducted in order to determine the characteristics of successful product development which are the factors that influence customers' choice of banking products and their adoption and have an impact on their satisfaction and loyalty. Also to determine whether the customers of Lebanese banks perceive their banks' new product development process to be successfully meeting their expectations and whether this perception contributes to their being satisfied, loyal and advocates of their banks. Another objective of the research was to determine whether there is a difference between the customers of Lebanese "Alpha" banks and the customers of the rest of the banks in terms of perceptions and impact of perceptions. An empirical study was performed, using survey research. The data was collected through a questionnaire administered to 140 respondents. The questionnaire was developed based on extensive literature review. The results of the study indicated that out of all the independent variables "products meeting customers' changing needs" and "products having friendly technology" have significant effect on customers' satisfaction, "products having anytime anywhere banking facilities", "convenience of products" and "products meeting present needs of customers" have significant effect on customers' loyalty, and "products meeting customers' changing needs", "innovative yet easy to use products" and "products having anytime anywhere banking facilities" have significant effect on customers' advocacy to their banks.
Pelatihan dan Pengkaderan Organisasi Kewirausahaan Pepsi KWU 2023
Authors: Hartati Hartati , Alimuddin Firman
Published: June 2024

Pengabdian Kepada Masyarakat ini dilaksanakan dengan tujuan: memberikan wawasan pengertahuan mengenai Kewirausahaan, memberikan wawasan mengenai pentingnya Kewirausahaan dalam melakukan bisnis atau usaha. dan memberikan bekal ilmu Pengetahuan dan Keterampilan dalam Kewirausahaan Pepsi KWU 2023. Sesuai dengan program kerja Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LPPM) Institut Ilmu Sosial Dan Bisnis Andi Sapada yang telah diwacanakan sebelumnya dalam bentuk program kerja, maka sasarannya peserta pelatihan adalah para pelaku UMKM yang berdomisili di Kecamatan Bacukiki Barat Kota Parepare.Jumlah peserta pelatihan yang mengikuti kegiatan ini adalah sebanyak 26 orang. Dari Pelaksanaan kegiatan pengabdian kepada masyarakat ini, maka kami dapat menarik kesimpulan bahwa Pelaksanan ini berjalan dengan lancar. Semua peserta antusias mengikuti acara hingga selesai dan merasakan manfaat pelatihan bagi kemajuan usaha mereka, dan Keberhasilan kegiatan ini atas dukungan pemerintah Kota Parepare, mendiskusikan peran kewirausahaan di PepsiCo dan dampaknya terhadap perekonomian. Kewirausahaan memainkan peran penting dalam perekonomian dengan menciptakan bisnis baru, lapangan kerja, dan inovasi.
Pelatihan Pengelolaan Scholar dan SINTA: Meningkatkan Efisiensi Administrasi dalam Kegiatan Tri Dharma
Authors: Syahril Muh. Akbar Fhad
Published: June 2024

Pelatihan pengelolaan akun Scholar dan SINTA bertujuan untuk meningkatkan efisiensi administrasi dalam kegiatan Tri Dharma perguruan tinggi, mencakup pendidikan, penelitian, dan pengabdian kepada masyarakat. Program ini membantu dosen membuat dan menautkan akun Google Scholar dan SINTA, serta mengelola data publikasi mereka. Hasil pelatihan menunjukkan dosen dapat memastikan publikasi terindeks dengan benar, meningkatkan sitasi, dan memperbaiki H-index. Selain itu, pelatihan ini juga meningkatkan visibilitas dan reputasi perguruan tinggi, berdampak positif pada akreditasi dan pemeringkatan institusi. Dosen juga memperoleh pemahaman manajemen sitasi, etika publikasi ilmiah, dan penyusunan laporan pertanggungjawaban Tri Dharma. Dengan demikian, pelatihan pengelolaan Scholar dan SINTA merupakan langkah strategis untuk meningkatkan kualitas pendidikan, kontribusi ilmiah dosen, serta mendukung perkembangan ilmu pengetahuan dan masyarakat.
Peran International Labour Organization (ILO) dalam Perlindungan HAM Pekerja Migran Indonesia
Authors: Madaniyah Anisa Sartika , Sophianandita Diandra Putri , Irawan Pradindha Tasya , Silalahi Yumi Lestari
Published: June 2024

As we know, Indonesians themselves have a fairly high level of competitiveness in terms of employment, which makes it quite difficult to get a job in the country. The minimality of employment makes many Indonesians choose to complain about their fate in another country, often referred to as migrant workers. Indonesia is one of the countries that has a considerable number of migrant workers and is scattered around the world. However, many of the Indonesian migrant workers have experienced human rights violations from their employers, such as discrimination, sexual harassment, physical and mental violence, wage withholding, and even unpaid wages. Human rights are inherent rights of every individual as long as they exist, including the right to education, freedom of religion, access to health facilities, the right to work, and other rights. To address the violations of migrant workers' rights, Indonesia joined the International Labour Organization (ILO), which is under the umbrella of the United Nations, as a reservoir that serves to provide protection for migrants. The ILO also protects workers' rights by improving living standards, hiring policies, working hours, working contracts, health care for workers, and dealing with all workers who have or are experiencing employment problems.
Site-Selection Process and Agents in FDI Promotion
Authors: Vaupot Zoran
Published: June 2024

In the last few decades, foreign direct investments have grown in their importance. We have access to a rich set of literature about FDI determinants and FDI promotion activities. The research about the site-selection process conducted by foreign investors is much less abundant. We propose an explanation to this phenomenon and possible changes in strategic approach by combining conclusions from existing literature concerning the topics about investment promotion process, its stakeholders, site-selection process, and institutional theory. The main conclusions are that a better customer-centric orientation is needed in the whole process of FDI promotion and that the relatively neglected importance of media should be improved by putting more attention on their role according to the findings of institutional theory; these are also the proposed axes of future research. The originality of the present research is the combination of theoretical findings with the practical experiences of the author gained while working as an international business consultant.
Hacia una idea política de cultura
Authors: Arese Laura
Published: June 2024

En los años treinta y cuarenta, Arendt se ocupa con intensidad del vínculo que los judíos europeos, en tanto actores políticos, mantienen con su propia inserción en la historia. Arendt llega a considerar este vínculo altamente problemático, pero no lo asocia a un carácter del judaísmo como tal, sino que lo concibe como rasgo adquirido cuyas raíces en el tiempo deben ser indagadas. Sostendremos que esta indagación conduce a un conjunto de reflexiones en torno a la idea de “cultura”, que no han recibido mayor atención en el campo de los estudios arendtianos y que resultan valiosas para el presente. Nuestro trabajo se propone reconstruir estas reflexiones recorriendo el complejo diálogo que la autora sostiene con distintas voces, especialmente de la propia tradición judía.
Una visión constitucional de la Ley Orgánica de Protección de la Seguridad Ciudadana
Authors: Dorado Sánchez Antonio , González-Deleito Domínguez Nicolás , Rodríguez Puñal Elicia , García Navarro Luis , Bustos Rubio Miguel , Dorado Picón Domingo , Navarrete Corral Estefanía , Navarro Mejía Ignacio , Varela José , Nebrera Gabella Francisco , Brasa Gayoso Julio , Díaz Franchy Raúl , Cortegoso Vaamonde Alberto
Published: June 2024

Pocas materias son más importantes para garantizar la defensa del ejercicio de los derechos fundamentales reconocidos en las sociedades libres que la seguridad ciudadana y orden público. En esta obra se analiza la compleja relación entre seguridad ciudadana y derechos fundamentales en el contexto de la Ley Orgánica 4/2015, de 30 de marzo, cuando ha transcurrido casi una década desde su entrada en vigor. Los autores analizan la materia de la mano de la jurisprudencia del Tribunal Constitucional, desgranando las tensiones entre libertad y seguridad, así como los desafíos actuales en la protección de derechos constitucionales que se encuentran involucrados en el ámbito de esta norma. Diversos expertos, desde profesionales del derecho hasta miembros de las fuerzas de seguridad, aportan una visión multidisciplinar y práctica sobre esta ley, ofreciendo un enfoque integral que trasciende lo teórico para comprender su impacto en la realidad social y legal.
ANÁLISIS DE LA JURISPRUDENCIA CONSTITUCIONAL EN RELACIÓN CON DETERMINADOS PRECEPTOS DEL RÉGIMEN SANCIONADOR
Authors: Nebrera Gabella Francisco
Published: June 2024

Pocas materias son más importantes para garantizar la defensa del ejercicio de los derechos fundamentales reconocidos en las sociedades libres que la seguridad ciudadana y orden público. En esta obra se analiza la compleja relación entre seguridad ciudadana y derechos fundamentales en el contexto de la Ley Orgánica 4/2015, de 30 de marzo, cuando ha transcurrido casi una década desde su entrada en vigor. Los autores analizan la materia de la mano de la jurisprudencia del Tribunal Constitucional, desgranando las tensiones entre libertad y seguridad, así como los desafíos actuales en la protección de derechos constitucionales que se encuentran involucrados en el ámbito de esta norma. Diversos expertos, desde profesionales del derecho hasta miembros de las fuerzas de seguridad, aportan una visión multidisciplinar y práctica sobre esta ley, ofreciendo un enfoque integral que trasciende lo teórico para comprender su impacto en la realidad social y legal.
LA POTESTAD SANCIONADORA: UNA MIRADA A LAS OBLIGACIONES DE LA ADMINISTRACIÓN Y A LOS DERECHOS DE LOS PARTICULARES
Authors: Cortegoso Vaamonde Alberto
Published: June 2024

Pocas materias son más importantes para garantizar la defensa del ejercicio de los derechos fundamentales reconocidos en las sociedades libres que la seguridad ciudadana y orden público. En esta obra se analiza la compleja relación entre seguridad ciudadana y derechos fundamentales en el contexto de la Ley Orgánica 4/2015, de 30 de marzo, cuando ha transcurrido casi una década desde su entrada en vigor. Los autores analizan la materia de la mano de la jurisprudencia del Tribunal Constitucional, desgranando las tensiones entre libertad y seguridad, así como los desafíos actuales en la protección de derechos constitucionales que se encuentran involucrados en el ámbito de esta norma. Diversos expertos, desde profesionales del derecho hasta miembros de las fuerzas de seguridad, aportan una visión multidisciplinar y práctica sobre esta ley, ofreciendo un enfoque integral que trasciende lo teórico para comprender su impacto en la realidad social y legal.
ENERGIA ELETRONUCLEAR
Authors: Wiltgen Filipe
Published: June 2024

Em um mundo que precisa de muita energia elétrica, e a grande maioria de nossas fontes de energia são pouco eficientes e escassas, muitas vezes dependentes do “humor” da natureza. A tecnologia eletronuclear nascida nas décadas de 30 e 40, é independente do clima, eficiente e abundante. Como tudo na natureza possui vantagens e desvantagens, a raça humana tem lidado com isso e amadurecido com a tecnologia. Fato é que a cada dia a energia eletronuclear parece ser uma das poucas alternativas viáveis para manter a vida humana no futuro. Este artigo discute a história, o uso, as tecnologias, as dificuldades científicas, além dos benefícios e cuidados necessários para a utilização consciente desta tecnologia nuclear.
Summary Of Trust Between Mother And Child Among Rural Junior High School Students
Authors: Chen Simeng
Published: June 2024

This article elucidates the importance of mother child trust from the emergence of "killing off" in Chinese society, difficulties in rural family education, and the crisis of identity faced by middle school students. Summarize from four aspects: trust types, trust factors, trust connotations, and trust fields, and point out the shortcomings of existing research. Research has found that research methods on maternal child trust among rural junior high school students focus on quantitative research, lacking qualitative research; The selection of research samples has limitations and has not fully considered the diversity of rural areas; Current research mainly focuses on the trust relationship between mother and child, while ignoring the impact of other family members, schools, communities, and other factors on mother child trust; The existing foreign theoretical framework may not be fully applicable to rural areas in China; At the same time, there is also a lack of attention to practical applications.
Recent Advances in Genetic Mutations in Papillary Thyroid Carcinoma
Authors: Xing ZhiJing , Zhu Ping , Ding Caixia , Wang Xiaomin , Yan Jun , Bai Jie , Li Lin
Published: June 2024

Papillary thyroid carcinoma (PCT), follicular origin are divided into RAS-like malignancies and BRAF-like malignancies according to their molecular characteristics and aggressiveness. With the continuous development of the molecular level, genetic mutations are significant in the diagnosis, treatment and prognosis of papillary thyroid carcinoma. This paper discusses the latest progress of papillary thyroid cancer gene mutation and its clinical application, in order to provide more efficient diagnosis and treatment means for patients.
Recuperación Ambiental de Ríos Urbanos: Río Medellín. Medellín – Colombia
Authors: Jaramillo-Londoño Juan
Published: June 2024

While rivers have allowed for the urban development of many cities, thanks to the establishment of industries and homes on their banks, the riverbeds and surrounding green spaces have deteriorated, turning them into high-risk areas for the populations settled there. In recent years, programs have been proposed to recover the channels of these rivers, not only from an aesthetic and ecological point of view, improving water quality and converting these sources into integrating axes of development, linking their landscape harmoniously with the city.
A Região de Estudos: o Meio Físico e o Espaço Humano
Authors: Vieira Eliane , Dias Gustavo , Almeida Pedro
Published: June 2024

This chapter presents an evaluation of changes that have occurred in the Izidora region (Belo Horizonte metropolitan area, Minas Gerais, Brazil). The study area comprised an informal settlement within the Macacos stream drainage basin and surrounding properties (Casa Francisco and Fazendas Werneck and the EPA Group). The study area was characterized, its hydrography, morphology and pedology, addressing the area's erosion potential and the occupation process over the years. In the region there is a predominance of two classes of soils: Dystrophic Red-Yellow Oxisols (LVAd8), occupying the northern portion of the Macacos stream basin, these are deeper, very weathered soil with a yellowish or yellowish-red color, thus covering most of the occupation Vitória and to the south dystrophic Red-Yellow Argisol (PVAd8), occupying regions of lower altitudes, more clayey soils, also yellowish-red in color, with deep and well-drained soils. The region has altitudes that vary from 715 to 873 m. After the establishment of the occupation, the area topography has changed, with interventions to build streets, simple houses and small commercial stores. Before the occupation, the runoff was directed to watercourses in the region, but it soon developed other routes, mainly following open streets, where sediment accumulated, and consequently invaded homes located in the lowest areas of the land. Until 2013, it was observed that the Macacos basin land uses remained predominantly classified as Vegetation and Exposed Soil. From 2014 onwards, the areas occupied by urban settlements expanded to the north, northwest, east and southwest of the basin. The areas with the greatest erosion potential are those more affected by natural vegetation removal. These areas are in the Vitória Occupation area and the regions with exposed soil. Therefore, measures that seek to recover vegetation, interventions that promote the return of flow to the riverbed and sediment containment actions can improve the situation of the Vitória Occupation.
Neuroestrogens facilitate male-typical behaviors by potentiating androgen receptor signaling in medaka
Authors: Nishiike Yuji , Maki Shizuku , Miyazoe Daichi , Nakasone Kiyoshi , Kamei Yasuhiro , Todo Takeshi , Ishikawa-Fujiwara Tomoko , Ohno Kaoru , Usami Takeshi , Nagahama Yoshitaka , Okubo Kataaki
Published: June 2024

In rodents, estrogens aromatized from androgens in the brain, also known as neuroestrogens, are essential for the development of male-typical behaviors. In many other vertebrates including humans and teleost fish, however, androgens facilitate these behaviors directly via the androgen receptor without aromatization into estrogens. Here we report that male medaka fish lacking Cyp19a1b (a subtype of aromatase predominantly expressed in the brain) exhibit severely impaired male-typical mating and aggression, despite elevated brain androgen levels. These phenotypes can be rescued by estrogen administration, indicating that neuroestrogens are pivotal for male-typical behaviors even in non-rodents. Our results further suggest that neuroestrogens facilitate male-typical behaviors by potentiating androgen action in the brain via the direct stimulation of androgen receptor transcription, thereby revealing a previously unappreciated mechanism of action of neuroestrogens. We additionally show that female fish lacking Cyp19a1b are less receptive to male courtship and conversely court other females, highlighting the significance of neuroestrogens in establishing sex-typical behaviors in both sexes.
Peasant Politics of the Twenty-First Century
Authors: Edelman Marc
Published: June 2024

This book illuminates the transnational agrarian movements that are remaking rural society and the world's food and agriculture systems. The book explains how peasant movements are staking their claims from farmers' fields to massive protests around the world, shaping heated debates over peasants' rights and the very category of “peasant” within the agrarian organizations and in the United Nations. The book chronicles the rise of these movements, their objectives, and their alliances with environmental, human rights, women's, and food justice groups. It scrutinizes high-profile activists and the forgotten genealogies and policy implications of foundational analytical frameworks like “moral economy,” and concepts, such as “food sovereignty” and “civil society.” The book charts the struggle of agrarian movements in the face of land grabbing, counter agrarian reform, and a looming climate catastrophe, and celebrates engaged research from Central America to the UN Human Rights Council in Geneva.
PENSAR, CONCEPTUALIZAR Y OPERACIONALIZAR LA SUSTENTABILIDAD: CONCEPTOS, MÉTODOS Y RESULTADOS DESDE EL CENTRO DE DESARROLLO URBANO SUSTENTABLE
Authors: Fuentes Luis , Greene Margarita , Rodríguez Sebastián , Señoret Andrés , Figueroa Cristhian , Berríos Emilio , Henríquez Cristián , Ruiz-Tagle Javier , Link Felipe , Salazar Gonzalo , Rehner Johannes , Truffello Ricardo , Valenzuela-Levi Nicolás , Navarrete Pablo , Ramírez María , Flores Mónica
Published: June 2024

El Centro de Desarrollo Urbano Sustentable (CEDEUS) propone comprender la sustentabilidad como el proceso a través del cual las comunidades florecen de forma armónica tanto en las generaciones actuales como en las futuras. Diferentes investigaciones han tomado esta definición y discutido ¿qué tipologías de barrio son más sustentables? y ¿cómo la percepción y experiencia de las personas releva prácticas, usos del espacio y lugares significativos que contribuyen a la comprensión de la sustentabilidad? En este documento se muestran las principales metodologías, resultados y aprendizajes de este proceso, para así, contribuir a la reflexión sobre cómo las comunidades pueden transitar hacia la sustentabilidad urbana.
Coleção Festejo Maior: possible links between design and visual anthropology in the production of photographic books
Authors: Nery Cristiane , Silva Sérgio Antônio
Published: June 2024

The Photographic Book is an important support as an item that covers the photographic creation of a project in different ways (FERNÁNDEZ, 2011). The justification and problem of this work is to show that Photography, here, is not just a piece of data to be analyzed. It is part of the results obtained throughout the development of a project. To address this topic, the article deals with the making of photograpic books when developed based on the Ethnographic Method and the possible links between Design Methodology and Visual Anthropology. To this end, the objective here is to analyze the production of digital books from the Feast of Brotherhood of Our Lady of the Rosary of the Blacks Collection (Coleção Festejo Maior), which portrays six different Guardas de Congado  – Brotherhoods of Our Lady of the Rosary of the Blacks – from the metropolitan region of  Belo Horizonte – MG - Brazil. The books were developed from research and extension projects in 2015 at the School of Design  – Escola de Design (ED) / Universidade do Estado de Minas Gerais (UEMG) – and were presented at P&D Design – Brazilian Congress of Research and Development in Design. The methodology used was qualitative (GIL, 2017), focusing on Ethnography and Visual Anthropology (COLLIER JR., 1973; SAMAIN, 2012) and the development of Design products (BONSIEPE, 2012). In this way, it can be observed that photography books or photobooks are a support that allows the development of a photographic project based on consistent methodologies, which allows us to conclude that the use of photography goes beyond field research data, becoming a protagonist in projects research and extension.
The Effect of Implementing Green Accounting and Material Flow Cost Accounting (MFCA) on the Value of Manufacturing Companies
Authors: Fitriani Nurikke Agus , Sayekti Yosefa , Irmadariyani Ririn
Published: June 2024

This article aims to determine the effect of implementing green accounting and material flow cost accounting (MFCA) on the value of manufacturing companies. This research uses secondary data in the form of an Annual Report which is accessed via the BEI page which is accessed via the relevant manufacturing company's website. The reporting period used is the period 2018 to 2022. The population in this research is the annual reports of manufacturing companies listed on the BEI and the websites of related manufacturing companies as secondary data sources. Using purposive sampling technique to select samples from manufacturing companies listed on the BEI. The data analysis method used is multiple linear regression analysis. The research results show that Green Accounting on Company Value shows a significant positive influence. This proves that the higher the Green Accounting will increase the Company Value. Material Flow Cost Accounting on Company Value shows a significant positive influence. This proves that the higher the Material Flow Cost Accounting will increase the Company Value. The result of this research can add and contribute to development of theory regarding the application of Green Accounting and Material Flow Cost Accounting (MFCA).
Impact of Bauxite Mining on Heavy Metal Levels in Kara Kara Blue Lake and Associated Active Tailing Pond
Authors: Adams Mayon , Maximus Josephine Kawa , Husbands Kerion
Published: June 2024

Bauxite exploration and production have significant negative impacts on ecological systems, primarily due to the high distribution of heavy metals in the environment. Post-bauxite mining reclamation efforts are most times inadequate. As a result, some abandoned pit mines have turned into lakes, now used for recreational activities. This study examines the heavy metal distribution in two locations affected by bauxite mining: the recreational Kara-Kara Blue Lake (BL) and the active Tailing Pond (TP). Using X-ray fluorescence, ten sediment samples from these sites were analysed for metals such as Al, Co, Cd, Cr, Cu, Fe, Mg, Mo, Ni, Pb, Ti, and Zn. Data analysis was conducted using Microsoft Excel, SPSS, and JASP software. The heavy metals in the Tailing Pond demonstrated a decreasing sequence of Fe > Ti > Al > Mn > Ni > Cd > Co > Cr > Zn > Pb > Mo > Cu, while in Blue Lake, the order was Ti > Fe > Mn > Co > Cr > Cd > Ni > Mo > Zn > Pb > Cu > Al. The study employed the Contamination Factor (CF) and Pollution Load Index (PLI) to evaluate pollution levels, revealing higher contaminant levels in the tailings pond than in Blue Lake, with PLI values of 1.06 and 0.83, respectively. Although Blue Lake appears relatively unpolluted and suitable for recreation, both lakes' elevated Ni, Cd, and Cr levels necessitate continuous monitoring to mitigate long-term exposure risks.
Delving on the Experiences of Educators on Professional Development of National Educators Academy of the Philippines: A Case Study
Authors: G. Gonio Yvette , M. Bauyot Marleonie
Published: June 2024

Educators are the carriers of knowledge and are responsible for its transfer. This qualitative case study examined six participants who actively integrated the National Educators Academy of the Philippines (NEAP) professional development into their practice. Five out of six came from the mega-sized secondary schools with two teachers, two master teachers, a school head; and one supervisor, a Division Representative. The six contributors were from the Division of Panabo City, selected through purposive sampling. Data were analyzed using thematic analysis. The study identified several common themes regarding the integration of NEAP learning into instructional and leadership practices, such as the adoption of comprehensive teaching and learning models, student-centered approaches, strategic planning, and strong support systems. Additional themes included mentorship, professional collaboration, and reflective practice. However, challenges requiring improvement were also noted, such as enhancing interactive group dialogue and incorporating research-based learning. Two main themes emerged regarding the understanding of monitoring and evaluation for further improvement: assessment and feedback provision. Recommendations included a careful examination of current and outdated policies, addressing issues related to curriculum overload, enhancing sources of teaching and learning materials, introducing stress-management activities, supporting research-related initiatives, ensuring clear communication, creating feedback loops, and organizing interactive workshops. Participants provided positive feedback on the integration of NEAP learning into their instructional and leadership practices. They appreciated and implemented NEAP-inspired approaches in their classrooms and schools. The study revealed that teachers were not only receptive to these changes but were also committed to the overall development of their students. Their participation in various training programs, workshops, seminars, scholarships, and courses indicated their desire to improve both personally and professionally.
Grounding Quality Education from the Experiences of High School Students in Selected Secondary Schools in the Philippines
Authors: Baylon III Vicente T.
Published: June 2024

Grounding Quality Education from the Experiences of High School Students, in Selected Secondary Schools in the Philippines. This study explored the experiences of High School Students from two different school in the Philippines. This task is entailed the identification of “Lived encounters of students in terms of accessibility of education, delivery of education, teachers and methodology, and students managing the overall experiences.
Aims: The study aimed to make a detailed and comprehensive inquiry into the Lived-Experiences of High School students with a view to develop an essential recommendation for students, teachers, supervisors, Department of Education, and National Government officials.
Scope and Limitation of the Study: The study focused on lived experiences of 10 selected high school students enrolled in public school and 10 selected high school students enrolled in private school and comparison of the differences in their lives and experiences inside their classroom.
Research Design: This observational analytic case control uses the grounded-phenomenological method of research. This method allows the researchers to investigate deeply into the subjective experiences and perspectives of the high school students.
Results: In view of quality education, The quality education is to provide an environment for learning in order to eliminate the complex students’ school problems with the right accessibility and sustainability for education with the help of expected government (DepEd) programs and the vital parts of students in the educational system.
Conclusion and Recommendation: The successful Quality Education starts with good student assessment of needs are those who manage student consistent learning, sustained-satisfied, and good students outcomes which provided them of awareness, knowledge, skills and preparedness for the future employment.
Effect of Cucumber (Cucumis sativus) Fruit Homogenate on Hypotonicity– induced Haemolysis of Red Blood Cell
Authors: Agatemor Uzuazokaro Mark-Maria , Nwodo Okwesili Fred Chiligue
Published: June 2024

Background: Several findings and reports show that people with high intake of Cucumis sativus (Cucumber) have relief in pains, swelling and other inflammatory signs. Human red blood cell membrane stabilization has been used as a method to investigate the mechanism of action of anti-inflammatory drugs. The anti-inflammatory activity of cucumber has been demonstrated in previous study. In this study, we aimed at assessing the effect of cucumber (Cucumis sativus) fruit homogenate on hypotonicity – induced haemolysis of red blood cell.
Methods: Whole fresh blood (3 ml) was collected from healthy volunteer into plastic tubes containing 0.1 volume of 3.8% trisodium citrate and used within 8 hr. The blood sample was centrifuged at 3000 x g for 10 min and the supernatant (plasma) discarded. The pellet was washed twice by resuspending in a volume of normal saline equal to the volume of the supernatant (plasma) and centrifuged at 3000 x g for 10 min. The pellet (0.1 ml) was resuspended in 2.5 ml of normal saline and used as the red blood cell (RBC).
Results: The results revealed that cucumber (Cucumis sativus) fruit homogenate significantly (p ˂ 0.05) inhibited hypotonicity-induced red blood cell haemolysis when compared to indomethacin (a known standard drug).
Conclusion: Cucumber has membrane stabilization effect on the red blood cell.
Effect of Tillage Practices and Integrated Nutrient Management on Soil Physicochemical Properties and Yield of Cowpea (Vigna unguiculata L. Walp) at Uttar Pradesh, India
Authors: Pati Koushik , David Arun Alfred , Thomas Tarence , Bharose Ram , Toppo Neha , Reddy Iska Srinath
Published: June 2024

A field investigation was conducted at Central Research Farm of Department of Soil Science and Agricultural Chemistry at Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, Uttar Pradesh, India during Zaid season of 2023. The experimental plot was laid down into a randomized block design with 9 treatments replicated thrice, consist of 3 levels each of tillage practices and RDF (0 %, 50%, 100%) and 1level of vermicompost (5 t ha -1). Results revealed that maximum bulk density (1.29 Mg m-3) and soil pH (7.10) were found in T1 (Tillage @ 0% + RDF @ 0% +VC @ 5t ha-1). The others soil parameters like porosity (55.60 %),water holding capacity (46.63 %), organic carbon (0.49 %), electrical conductivity(0.25 dS m-1), available Nitrogen (331.54 kg ha-1), available Phosphorus (28 kg ha-1), available Potassium (193.73 kg ha-1 ) were recorded maximum in T9 (Tillage @ 100% + RDF @ 100% +VC @ 5t ha-1) .Whereas best yield (150.56 q ha-1 ) was also recorded in T9 (Tillage @ 100% + RDF @ 100% +VC @ 5t ha-1) .Economic parameters like gross return (₹271008.00 ha-1) and net return (₹152323.00 ha-1) were found to be maximum in T9 (Tillage @ 100% + RDF @ 100% +VC @ 5t ha-1) and best cost benefit ratio (C: B) was recorded as (1:2.28) in treatment T9 (Tillage @ 100% + RDF @ 100% +VC @ 5t ha-1). Integrated approach of application of RDF (NPK), vermicompost along with 100% tillage practices found to be the best treatment as the soil parameters and plant growth parameters significantly affected with the different levels of nutrient and tillage practices.
Millets and Indigenous Food Systems in Indian Subcontinent: Revitalization, Resilience and Sovereignty
Authors: Yadav Vicky , Lal Sudhanand Prasad , Gaur Rishabh Singh , Malik Biswajit
Published: June 2024

Millet serves as a nutritional powerhouse, brimming with minerals, protein, beneficial fats, calcium, and an array of vital nutrients. Of all the millet varieties, Ragi takes the lead with its remarkable calcium content. Millets play a pivotal role in promoting good health, exhibiting the capacity to combat a range of diseases, even including cancer. Furthermore, these grains are highly recommended for individuals dealing with diabetes, forming a valuable part of the diet for diabetic patients. Presently, millet cultivation spans across 131 nations, with India prominently positioned as a frontrunner, contributing 41% to the global millet production. Remarkably, India's stature extends further as it clinches the fifth spot among the world's millet exporters. Noteworthy is the fact that in December 2018, India's proposal for designating 2023 as the International Year of Millets was embraced by the FAO, subsequently declared in March 2023. This paper delves into a comprehensive exploration of millets, encompassing their definition, a nutritional juxtaposition with cereals, accrued health advantages, contribution of millet production to the attainment of SDGs, a comprehensive overview of millet's cultivation landscape concerning geographical extent, production, productivity, and export trends. Additionally, a substantial focus is dedicated to elaborating on the significance and implications of the International Year of Millets, reflecting India's proactive role in enhancing global awareness about these grains.