bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination mechanical properties and permeability of porous titanium alloy bone implants, including under conditions of their interaction with biological fluids
Authors:   Lavrentyev Institute of Hydrodynamics SB RAS, Fedorova Natalya , Kosinov Aleksandr
Published: May 2024

Additive manufacturing technologies make it possible to create porous implants with mechanical properties equivalent to natural bone. At the same time, a number of new problems arise, including determining the mechanical properties of such structures. This study is aimed at obtaining the mechanical parameters of porous titanium alloy for bone implants, including under conditions of their interaction with biological fluids. Mechanical properties were obtained for nine types of structures: three types of porosity for each of the three types of structure orientation. The considered porosity of the structures from 41–52 % lies in the porosity range of cancellous bone. Young's modulus was obtained from 10 to 22 GPa and Poisson's ratio was obtained from 0.136 to 0.337, as the results of uniaxial compression test. The Young's moduli of the standard 47 % porosity are closest to the moduli of the cortical bone 15–16 GPa. The structure configuration with the lowest Young's modulus is recommended for the manufacture of implants for patients with high porosity of bone tissue. The experiments considered the interaction of porous structures with biological fluids. Poroelastic effects were not found for structures with pore space filled by collagen under uniaxial compression up to 5000 N. Experiments to determine the permeability were carried out for three types of porosity with the orthogonal orientation of the structure. The permeability coefficient varied from 0.99∙10-10 to 3.6∙10-10 m2 for an aqueous solution of glycerol, simulating blood, and from 1.4∙10-10 to 2∙10-10 m2 for gelatin, simulating collagen formation during primary osteointegration. The results obtained will be useful in developing new approaches to modeling porous implants in biomechanics.
Comparison of finite element modeling approaches for Ti6Al4V porous bone implants
Authors:   Lavrentyev Institute of Hydrodynamics SB RAS, Fedorova Natalya
Published: May 2024

Additive technologies have made it possible to make a significant breakthrough in the development and production of personalized porous implants, which have clear advantages over monolithic predecessors. At the same time, engineers are faced with a number of new tasks, one of which is correct and effective numerical modeling of porous implants in the process of solving optimization problems. The study compares approaches to numerical modeling of porous titanium for bone implants, taking into account differences in the mechanical parameters of the material and the geometry of the models. The detailed geometry of the structure of 9 models is considered, for which two variants of material parameters are specified: pure Ti6Al4V alloy and experimental ones obtained for specimens printed from Ti6Al4V powder. As a proposed approach to homogenizing the structure, a continuum model of a cylinder is considered, for which the experimental properties of the specimen’s material are specified. The numerically obtained values of Young's moduli for each approach are compared with those obtained in the experiment. It has been established that when setting the properties of a pure alloy, the calculated Young's modulus exceeds the experimental one by 83–92 %. The closest thing to experiment is detailed modeling of geometry with setting the experimental properties of the material structure, while the calculated Young's modulus does not exceed the experimental one by more than 10 %. However, in this case the calculation takes from 2 to 8 hours. In the case of continuum modeling, the calculated Young's moduli exceed the calculated moduli in detailed modeling by no more than 11 %, while the calculation lasts no more than 1 minute. Based on this, it is proposed to use a continuum approach to modeling implants in the process of calculating the optimization of their shape, as an initial iteration before detailed modeling of the structure. As material properties, it is necessary to use the mechanical parameters of the structures, previously obtained from uniaxial compression experiments. Using the properties of a pure alloy will lead to results that significantly exceed the actual ones when calculating the porous structure.
University Libraries in Türkiye: Past to Present - A Comprehensive Analysis
Authors: Demir Güler , Keseroğlu Hasan Sacit
Published: May 2024

University libraries play a vital role in the academic landscape by providing a wide range of essential support and services to their members. From research materials and academic resources to access to cutting-edge technology and expert staff, these libraries are at the forefront of fostering a culture of learning, collaboration, and innovation both within their physical spaces and online. Their importance extends beyond the academic environment, as they are also expected to contribute to the development of their respective countries by providing the resources and tools necessary to support a strong and thriving knowledge economy. The objective of this research is to provide a detailed analysis of the situation and challenges experienced by university libraries in Türkiye. This study utilized descriptive and documentary scanning methods to analyze and interpret data obtained from a wide range of both domestic and foreign literature, as well as official primary documents and media. The scope of the study was determined by historical, managerial, legal, and technological problems faced by Türkiye’s university libraries. To ensure systematic integrity, the study grouped various dimensions thought to have a direct or indirect impact on university libraries in Türkiye under different headings. These headings, which constitute the scope of the study, include: “Legislation, organization, and administrative structure”; “Policy, regulations, and standards”; “Budget, building, collection management, human resources, user-related matters, and other relevant issues”; “Collaborations”, and “Information and communication technologies”. By taking into account the historical context, this study aims to offer a comprehensive understanding of the issues that these libraries have faced and continue to face in the present day. The findings of this research indicate that the challenges encountered by university libraries in the past have yet to be effectively addressed and resolved. The study’s methodical, multifaceted, and multidimensional approach to evaluating university libraries, both in the historical context and current situation, presents a unique perspective. The comprehensive and in-depth evaluation process applied in this study is unparalleled and distinguishes it from prior studies in the field. This approach provides a holistic view of university libraries, allowing for a more detailed and accurate assessment of their overall performance.
Dinoflagellate composition and environmental conditions in the Xuan Dai Bay, South-Central Vietnam
Authors: Huynh Thi Ngoc Duyen , Tran Thi Minh Hue , Tran Thi Le Van , Phan Tan Luom , Nguyen Tam Vinh , Nguyen Ngoc Lam , Doan- Nhu Hai
Published: May 2024

The dinoflagellate community was investigated in association with environmental factors using a data set in April 2021 and April 2022 in Xuan Dai Bay, South-Central Viet Nam. Environmental variables, including physical parameters and dissolved inorganic nutrients, were measured in April 2022. Seventy-three dinoflagellate taxa were identified for Xuan Dai Bay. There was a significant difference in the number and abundance of dinoflagellates between two parts of the bay, the upper and lower bay. The study showed that dinoflagellates favored an area with good water exchange and were less affected by aquaculture activities. Principal component analysis (PCA) was used to explore the relative abundances of different phytoplankton groups, their diversity indices, and environmental variables at the surface and bottom layers of the two parts of the bay. The results showed that dinoflagellates correlated to physical parameters (e.g., PAR, salinity, temperature) at the surface layer and nutrients at the bottom layer. Dinoflagellates and diatoms are mixotrophic and strongly correlated at the bottom layer in Xuan Dai Bay. This strong relationship in the bay was because of the dominance of a heterotrophic genus, Protoperidinium. The present study provided characteristics of the dinoflagellates in Xuan Dai Bay and the possible impacts of environmental parameters on their abundance. The results can be used for further studies and possibly managing of dinoflagellate blooms in coastal waters.
Józef Jakubowski (1899–1984) – activist in scout, community, and émigré organisations in the light of Polish and French archival resources
Authors: Pachowicz Anna
Published: May 2024

The main purpose of this paper is to provide an insight into the life, activities, and preserved archival documents concerning Józef Jakubowski (1899–1984), whose work in support of Polish emigrants residing in France during the Second World War deserves highest recognition and respect. Jakubowski was born in Warsaw, where he spent his childhood, completed primary and secondary education, and began his studies at the Warsaw University of Technology in 1917. He was was actively involved in the scouting movement. His participation in the Polish–Soviet War forced him to leave the university . It was only in 1924 that he completed his higher education at another university, the Higher School of Commerce. His professional life also started in Warsaw, where he worked for the Association of Polish Merchants until 1939. His life was interrupted by the Second World War, and he decided to emigrate first to Switzerland and then to France. At that time of his life, he became involved with the Polish Red Cross. He was primarily involved in developing forms of aid and organising support for Poles in France. Once the Polish Red Cross was banned from further activities, he worked in the Welfare Society for the Poles in France. He cooperated with the Polish Resistance Movement in France and with military authorities on the evacuation of the Polish armed forces to England, as well as with many institutions, including the French Red Cross, the Department of Social Welfare for Foreigners, the International Refugee Organisation, and the Association of Polish Veterans. The archival documents concerning Jakubowski, surviving at the Central Archives of Modern Records in Warsaw and at the Polish Library in Paris, make it possible to reconstruct not only the facts of his life but also the events related to the functioning of the institutions, organisations, and associations he worked for.
"Each bishop wears the violet of suffering on his face more than the violet of robes" – Review of the joint work "Prymas Stefan Wyszyński i Episkopat Polski", edited by R. Łatka and D. Zamiatała
Authors: Graniczkowski Sebastian
Published: May 2024

This article serves as a review of the collective work edited by Rafał Łatka and Dominik Zamiatała, entitled “Prymas Stefan Wyszyński i Episkopat Polski” (“Primate Stefan Wyszyński and the Polish Episcopate”), published by the Warsaw Institute of National Remembrance in 2023 as part of the “Bishops in the Realities of the Communist state” series. The individual chapters of the work were discussed, presenting the most important themes covered in them, such as the complexities associated with the nomination of Cardinal Wyszyński as Primate of Poland, in accordance with the will of his predecessor—Cardinal August Hlond; the Primate’s concern about new bishop nominations; Cardinal Wyszyński’s skillful combination of the primate’s office with the function of the chairman of the episcopate; the Primate’s unifying openness to cooperation with individual bishops, especially with his own secretary, and then the Metropolitan of Poznań, Archbishop Antoni Baraniak, or the Metropolitan of Kraków, Karol Wojtyła; the Primate’s relations with hierarchs representing specific entities. Some shortcomings were also noted, such as the omission of Primate Wyszyński’s relations with two dioceses or the incomplete development of relations with the Kraków metropolis. Finally, reference was made to the critical edition of the last letter of Primate Wyszyński to John Paul II, included in the publication under discussion.
Participation as “attingere” and Saint Thomas’ commentary on John 6:57
Authors: Von Voorst Johannes
Published: May 2024

Saint Thomas Aquinas’ notion of participation is developed by Cornelio Fabro with the notion of ‘attingere’. In this essay I address the importance of ‘participare’ as attingere by uncovering it in Aquinas’ commentary on John 6:57. I introduce the notion of supernatural participation of grace and Fabro’s development of the notions of ‘attingere’ as ‘partecipare per similitudinem’ and ‘partecipare per operationem’ for a fuller understanding of the notion of participation that Fabro holds to be so essential. Afterwards we will see a concrete example in the uncovering of said notions in the Angelic Doctor’s commentary on a central verse of the Bread of Life discourse. Thus, we will be able to see both (a) the importance of the notion of ‘participare’ and ‘attingere’ in Saint Thomas’ work, and (b) have a more profound understanding of a key aspect of the thought of the Doctor Communis on grace and the Eucharist.
Protection of Sexual Violence Victims from the Perspective of Maqāṣid al-Sharī‘ah
Authors: Musyafa'ah Nur Lailatul , Nugraha Ahlam , Akbar Muhammad Ilham , Kurniawan Cecep Soleh
Published: May 2024

The Witness and Victim Protection Agency (LPSK) in Indonesia plays a crucial role in safeguarding individuals affected by sexual violence. This article evaluates the LPSK’s authority in protecting sexual violence witnesses and victims through the lens of maqāṣid al-sharī‘ah. Employing a normative research approach, laws and regulations relevant to witness and victim protection were analyzed. Data, gathered via literature review, underwent deductive analysis. The study highlights that LPSK’s authority is governed by Laws No. 13/2006 (amended to No. 31/2014) on the Protection of Witnesses and Victims and Law No. 12/2022 on Criminal Acts of Sexual Violence. While these laws establish a vital framework for safeguarding sexual violence victims, their execution reveals notable weaknesses. To achieve the highest realization of maslaḥah in maqāṣid al-sharī‘ah, enhancing the protection of witnesses and victims is imperative. LPSK should focus on five key aspects: ḥifẓ al-dīn (protecting victims in accordance with God’s commandments, ḥifẓ al-nafs (providing medical protection, ḥifẓ al-nasl (administering punishment to perpetrators violating victims’ dignity, ḥifẓ al-'aql (imparting knowledge about victims’ rights, and ḥifẓ al-māl (supporting victims in obtaining restitution or material needs.
Analisis Penerapan Inkuiri Secara Daring dengan Scaffolding Berbantuan Geogebra Materi Fungsi Kuadrat
Authors: Mufidha Nurul , Subanji Subanji
Published: May 2024

This study aims to analyze and describe the application of online inquiry learning with the GeoGebra-assisted scaffolding technique on quadratic function material in grade IX students at SMP Negeri 1 Malang. This research is a qualitative descriptive study, with the instruments used in the form of a learning implementation sheet, student activity sheets, student learning outcomes tests, questionnaires, and interviews. The results showed that learning according to the steps of inquiry had gone very well with an average implementation score of 94.5. Learning is carried out by scaffolding through questions directed at focusing, inviting, reminding, clarifying, and evaluating so that it is compatible with inquiry learning which is applied online. Student learning outcomes reached an average score of 73 daily tests in the good category.
Pengembangan Media Pembelajaran Matematika Berbasis Android Menggunakan Adobe Flash CS 6 Pada Materi Trigonometri
Authors: Pujiarti Indah , Dwi Ferdiani Rosita , Fayeldi Trija
Published: May 2024

In the era of industrial revolution 4.0 and community technology 5.0, smartphones are currently very widely used by educational practitioners as a medium for learning mathematics. It aims to attract students' interest in learning mathematics that is considered difficult by students such as trigonometry material. A lot of software is used to make android-based learning media for smartphones, one of which is Adobe Flash CS 6. This research is ADDIE version development research which includes five levels, specifically: Analysis, Design, Development, Implementation, and Evaluation. The instruments used are professional validation questionnaires and scholar response questionnaires. The validation expert concludes that Android-based mathematics learning media using Adobe Flash CS 6 on trigonometry material is included in the category "very feasible and can be used with a little revision." While the results of the student response questionnaire obtained a very good percentage of student responses and got the "very practical" category.
Analisis Kemampuan Pemecahan Masalah Numerasi Siswa Berdasarkan Tingkat Kecemasan Matematis
Authors: Susanti Seftyana Ayu , Budiarto Mega Teguh , Setianingsih Rini
Published: May 2024

The descriptive study analyzed the skills of vocational school students with low, medium, and high levels of mathematical anxiety in terms of their problem-solving abilities. It used a qualitative approach to examine the various mathematical content strands and scientific contexts of the learners. Its findings were based on the notion of the problem-solving stage by Polya, Newman,  as well as Krulik and Rudnik. The data collected during the study was gathered through a written test, which involved asking the participants to complete a questionnaire about their mathematical anxiety levels before they were asked to solve numeracy problems. The results of the study revealed that students with high levels of anxiety were more prone to experiencing problems with problem-solving. The findings of this study are valuable to mathematics educators and researchers. It is also expected to contribute to the development of effective problem-solving strategies for students.
How Can Generative AI Enhance the Well-being of Blind?
Authors: Bendel Oliver
Published: May 2024

This paper examines the question of how generative AI can improve the well-being of blind or visually impaired people. It refers to a current example, the Be My Eyes app, in which the Be My AI feature was integrated in 2023, which is based on GPT-4 from OpenAI. The author’s tests are described and evaluated. There is also an ethical and social discussion. The power of the tool, which can analyze still images in an amazing way, is demonstrated. Those affected gain a new independence and a new perception of their environment. At the same time, they are dependent on the world view and morality of the provider or developer, who prescribe or deny them certain descriptions. An outlook makes it clear that the analysis of moving images will mean a further leap forward. It is fair to say that generative AI can fundamentally improve the well-being of blind and visually impaired people and will change it in various ways.
How Can GenAI Foster Well-being in Self-regulated Learning?
Authors: Hauske Stefanie , Bendel Oliver
Published: May 2024

This paper explores how generative AI (GenAI) can improve the well-being of learners within self-regulated learning (SRL) frameworks in the corporate context. In the “GenAI to Support SRL” section, it presents three custom versions of ChatGPT aimed at assisting learners. These so-called GPTs demonstrate the GenAI’s potential to actively support learners in SRL and positively influence their well-being. The “Discussion” and “Summary and Outlook” sections provide a balanced overview of the opportunities and risks associated with GenAI in the field of learning and highlight directions for future research. The results indicate that GenAI could improve the well-being of learners in SRL through providing personalized guidance, reducing feelings of stress, and increasing motivation and self-efficacy. At the same time, there are several challenges for companies and employees that need to be overcome.
Fair Machine Guidance to Enhance Fair Decision Making
Authors: Yang Mingzhe
Published: May 2024

Human judgment is often subject to bias, leading to unfair decisions. This is particularly problematic when assessments have significant consequences, underscoring the importance of guiding humans towards fairness. Although recent advancements in AI have facilitated decision support, it is not always feasible to employ AI assistance in real-world scenarios. Therefore, this study focuses on developing and evaluating a method to guide humans in making fair judgments. Our experimental results confirmed that our approach effectively promotes fairness in human decision-making.
Remote Possibilities: Where There Is a WIL, Is There a Way? AI Education for Remote Learners in a New Era of Work-Integrated-Learning
Authors: Jacoby Derek , Savage Saiph , Coady Yvonne
Published: May 2024

Increasing diversity in educational settings is challenging in part due to the lack of access to resources for non-traditional learners in remote communities. Post-pandemic platforms designed specifically for remote and hybrid learning---supporting team-based collaboration online---are positioned to bridge this gap. Our work combines the use of these new platforms with co-creation and collaboration tools for AI assisted remote Work-Integrated-Learning (WIL) opportunities, including efforts in community and with the public library system. This paper outlines some of our experiences to date, and proposes methods to further integrate AI education into community-driven applications for remote WIL.
Toward Autonomy: Metacognitive Learning for Enhanced AI Performance
Authors: Conway-Smith Brendan , West Robert L.
Published: May 2024

Large Language Models (LLMs) lack robust metacognitive learning abilities and depend on human-provided algorithms and prompts for learning and output generation. Metacognition involves processes that monitor and enhance cognition. Learning how to learn - metacognitive learning - is crucial for adapting and optimizing learning strategies over time. Although LLMs possess limited metacognitive abilities, they cannot autonomously refine or optimize these strategies. Humans possess innate mechanisms for metacognitive learning that enable at least two unique abilities: discerning which metacognitive strategies are best and automatizing learning strategies. These processes have been effectively modeled in the ACT-R cognitive architecture, providing insights on a path toward greater learning autonomy in AI. Incorporating human-like metacognitive learning abilities into AI could potentially lead to the development of more autonomous and versatile learning mechanisms, as well as improved problem-solving capabilities and performance across diverse tasks.
Embodying Human-Like Modes of Balance Control Through Human-In-the-Loop Dyadic Learning
Authors: Mannan Sheikh , Vimal Vivekanand Pandey , DiZio Paul , Krishnaswamy Nikhil
Published: May 2024

In this paper, we explore how humans and AIs trained to perform a virtual inverted pendulum (VIP) balancing task converge and differ in their learning and performance strategies. We create a visual analogue of disoriented IP balancing, as may be experienced by pilots suffering from spatial disorientation, and train AI models on data from human subjects performing a real-world disoriented balancing task. We then place the trained AI models in a dyadic human-in-the-loop (HITL) training setting. Episodes in which human subjects disagreed with AI actions were logged and used to fine-tune the AI model. Human subjects then performed the task while being given guidance from pretrained and dyadically fine-tuned versions of an AI model. We examine the effects of HITL training on AI performance, AI guidance on human performance, and the behavior patterns of human subjects and AI models during task performance. We find that in many cases, HITL training improves AI performance, AI guidance improves human performance, and after dyadic training the two converge on similar behavior patterns.
Decomposed Inductive Procedure Learning: Learning Academic Tasks with Human-Like Data Efficiency
Authors: Weitekamp Daniel
Published: May 2024

Human brains have many differently functioning regions which play specialized roles in learning. By contrast, methods for training artificial neural networks, such as reinforcement-learning, typically learn exclusively via a single mechanism: gradient descent. This raises the question: might human learners’ advantage in learning efficiency over deep-learning be attributed to the interplay between multiple specialized mechanisms of learning? In this work we review a series of simulated learner systems which have been built with the aim of modeling human student’s inductive learning as they practice STEM procedural tasks. By comparison to modern deep-learning based methods which train on thousands to millions of examples to acquire passing performance capabilities, these simulated learners match human performance curves---achieving passing levels of performance within about a dozen practice opportunities. We investigate this impressive learning efficiency via an ablation analysis. Beginning with end-to-end reinforcement learning (1-mechanism), we decompose learning systems incrementally to construct the 3-mechanism inductive learning characteristic of prior simulated learners such as Sierra, SimStudent and the Apprentice Learner Architecture. Our analysis shows that learning decomposition plays a significant role in achieving data-efficient learning on par with human learners---a greater role even than simple distinctions between symbolic/subsymbolic learning. Finally we highlight how this breakdown in learning mechanisms can flexibly incorporate diverse forms of natural language and interface grounded instruction, and discuss opportunities for using these flexible learning capabilities in interactive task learning systems that learn directly from a user’s natural instruction.
Protein N-Glycans in Healthy and Sclerotic Glomeruli in Diabetic Kidney Disease
Authors: Veličković Dušan , Shapiro John P. , Parikh Samir V. , Rovin Brad , Toto Robert D. , Vazquez Miguel A. , Poggio Emilio D. , O'Toole John F. , Sedor John R. , Alexandrov Theodore , Jain Sanjay , Bitzer Markus , Hodgin Jeffrey , Veličković Marija , Sharma Kumar , Anderton Christopher R. ,   for the Kidney Precision Medicine Project
Published: May 2024

Key Points

Multiomics performed on diabetic kidney disease biopsies revealed five N-glycan signatures of sclerotic glomeruli that significantly differed compared with healthy glomeruli.

Integrative spatial glycomics, proteomics, and transcriptomics revealed protein N-glycosylation characteristic of sclerotic glomeruli in diabetic kidney disease.

Background

Diabetes is expected to directly affect renal glycosylation; yet to date, there has not been a comprehensive evaluation of alterations in N-glycan composition in the glomeruli of patients with diabetic kidney disease (DKD).

Methods

We used untargeted mass spectrometry imaging to identify N-glycan structures in healthy and sclerotic glomeruli in formalin-fixed paraffin-embedded sections from needle biopsies of five patients with DKD and three healthy kidney samples. Regional proteomics was performed on glomeruli from additional biopsies from the same patients to compare the abundances of enzymes involved in glycosylation. Secondary analysis of single-nucleus RNA sequencing (snRNAseq) data were used to inform on transcript levels of glycosylation machinery in different cell types and states.

Results

We detected 120 N-glycans, and among them, we identified 12 of these protein post-translated modifications that were significantly increased in glomeruli. All glomeruli-specific N-glycans contained an N-acetyllactosamine epitope. Five N-glycan structures were highly discriminant between sclerotic and healthy glomeruli. Sclerotic glomeruli had an additional set of glycans lacking fucose linked to their core, and they did not show tetra-antennary structures that were common in healthy glomeruli. Orthogonal omics analyses revealed lower protein abundance and lower gene expression involved in synthesizing fucosylated and branched N-glycans in sclerotic podocytes. In snRNAseq and regional proteomics analyses, we observed that genes and/or proteins involved in sialylation and N-acetyllactosamine synthesis were also downregulated in DKD glomeruli, but this alteration remained undetectable by our spatial N-glycomics assay.

Conclusions

Integrative spatial glycomics, proteomics, and transcriptomics revealed protein N-glycosylation characteristic of sclerotic glomeruli in DKD.
Gordon, Donald, Fraser Hunter and Phil Freeman (eds). 2023. Revealing Trimontium: The Correspondence of James Curle of Melrose, Excavator of Newstead Roman Fort. Oxford: Archaeopress; 978-1-8032-7515-4 paperback £35.
Authors: Stewart Martha
Published: May 2024

This is a review of Revealing Trimontium: The Correspondence of James Curle of Melrose, Excavator of Newstead Roman Fort, edited by Donald Gordon, Fraser Hunter and Phil Freeman, published in 2023 by Archaeopress.
Empirical Realities? A Question of Basic Principle
Authors: Boeré Robyn Elizabeth
Published: May 2024

This article is a response to John Perry and Joanna Leidenhag’s book, Science-Engaged Theology. In this response, I focus primarily on the basic principle of science-engaged theology laid out by the authors on the first page of their book. Specifically, I invite both the authors and readers to think more deeply about (1) what it means to make scientific claims, (2) what it means for something to be an empirical reality, and (3) from what fields of study the insights of empirical investigation stem.
Okul Öncesi Çocukların Öz Düzenleme Becerilerinin Ego Sağlamlık Düzeylerine Etkisinin İncelenmesi
Authors: Liman Belgin
Published: May 2024

Öz düzenleme, yaşamın ilk yılarında kazanılması gereken temel bir beceridir; çocukluk, ergenlik ve yetişkinlik sürecinde olumlu ve olumsuz sonuçlara sebep olabilmektedir. Özellikle okul öncesi dönem, ego gelişiminde önemli bir süreçtir. Araştırmada öz düzenleme becerilerinin okul öncesi dönem çocuklarının ego sağlamlık düzeylerine etkisinin incelenmesi amaçlanmıştır. Ayrıca çalışmada çocukların öz düzenleme becerileri ve ego sağlamlık düzeyleri arasındaki ilişkiye bakılmıştır. Çalışma grubunu okul öncesine devam eden 5-6 yaş aralığındaki 309 çocuk ve anneleri oluşturmaktadır. Verilerin toplanmasında 4-6 Yaş Çocuklarına Yönelik Öz-Düzenleme Becerileri Ölçeği (Anne Formu) ve Çocuk Ego Sağlamlığı Ölçeği kullanılmıştır. Verilerin çözümlenmesi Pearson Korelasyon analizi ve CHAID analizi ile yapılmıştır. Sonuç olarak çocukların toplam öz düzenleme becerileri ve dikkat, çalışma belleği, engelleyici duygu, engelleyici davranış düzenleme ile ego sağlamlık düzeyleri arasında pozitif yönde anlamlı bir ilişki olduğu, çocukların öz düzenleme beceri düzeyleri arttıkça ego sağlamlık düzeylerinin de arttığı tespit edilmiştir. Araştırmada okul öncesi çocuklarında dikkat alt boyutunun çocukların ego sağlamlık düzeyleri üzerinde istatistiksel olarak manidar düzeyde birincil belirleyici etkiye sahip olduğu tespit edilmiştir. Ayrıca dikkati orta düzeyde olan çocuklardan engelleyici kontrol duygu davranışı yüksek olan çocukların ego sağlamlık düzeylerinin daha iyi olduğu tespit edilmiştir. Çocuklarda ego ve ego sağlamlığının desteklenmesi ve gelişimine önem verilmelidir. Araştırma sonuçları, çocukların ego dayanıklılığını geliştirmek için uygun müdahale adımları oluşturulmasına rehberlik edebilir.
Multi-electrode array recordings v1
Authors: Biagio Mercuri Nicola
Published: May 2024

MEA recordings in acute slices
Contra la evanescencia del criterio
Authors: Domínguez Gómez Eduardo
Published: May 2024

Se abordan en este volumen tanto asuntos que pueden tildarse de cotidianos o privados —por ejemplo, la moda femenina—, como otros de naturaleza esencialmente pública o social —las ideologías políticas, las mentalidades, los modos de ver el Descubrimiento de América, las historias de las culturas—. A todos los une, sin embargo, la búsqueda de relaciones entre los contenidos de la mente y los sucesos históricos, políticos, ideológicos y sociales, y la convergencia de disciplinas como la filosofía, la ciencia política, la sociología y, por supuesto, la historia, ámbito privilegiado del profesor Eduardo Domínguez.
Digital Futures: A Signal-Based Approach to Inclusive Digital Youth Work for Socially Vulnerable Youth
Authors: Vermeire Lotte , Van den Broeck Wendy
Published: May 2024

This article examines inclusivity in digital youth work initiatives which use and discuss media and technology. The research focusses on initiatives aimed at socially vulnerable youth. Socially vulnerable and digitally excluded youth face educational inequalities due to limited resources, such as inadequate hardware or lack of academic support at home (Correa et al., 2020; Faure et al., 2022; Garmendia & Karrera, 2019). Youth work as non-formal learning plays a crucial role here, possessing certain advantages that formal education does not have—for instance, the freedom to set needs-specific learning goals that are more responsive to societal signals. Through a two-fold comparative case study analysis, we delve deeper into the successful approaches to organising digitally inclusive digital youth work. The case studies (N = 14), located in Flanders, Belgium, were conducted through an in-depth analysis consisting of a QuickScan of practices and in-depth interviews with practice representatives. Our findings identify four success factors for the setup of digitally inclusive practices: (a) providing young people with the means to actively participate during the activity, (b) informing youth workers about digital inclusion factors, (c) providing youth workers with the means to seek help from other actors working on digital inclusion, and (c) including the target group in the creation process of the activity. Based on these four success factors, this study emphasises the importance of a signal-based approach that starts from the needs and talents of youth.
From Parliament to Party: The Gender‐Sensitive Parliamentary Group
Authors: Ahrens Petra , Meier Petra
Published: May 2024

Gender-sensitive parliaments are an emergent international norm. Research primarily focused on parliaments as gendered workplaces functioning with formal and informal rules and routines that either constrain or promote gender equality. We shift the focus to parliamentary groups and parties in public office as key actors in achieving a gender-sensitive parliament. We argue that they play a crucial role in many parliamentary systems and can actively contribute to gender-sensitive transformations. Building on the gender-sensitive parliament literature, we first explore the potential of parliamentary groups to improve parliamentary functioning across four aspects: representation, policy-making, engagement with societal interests, and groups as gender-sensitive workplaces. Secondly, we delve into the broader parliamentary and party contexts, recognizing how factors such as the diversity of parliamentary systems, organizational structures, parties in central office, and political dynamics shape parliamentary groups’ room for manoeuvre. We conclude by calling for further empirical, but especially conceptual, research to develop intersectionality-sensitive parliaments which we suggest are crucial for dismantling existing power hierarchies based on social markers.
Primary cytoreductive surgery followed by chemotherapy compared to neoadjuvant chemotherapy followed by cytoreduction as a treatment for stage III and IV ovarian cancer (literature review)
Authors: Sibirskaya E. V. , Nikiforova P. O. , Rabadanova N. R.
Published: May 2024

Standard treatment for advanced ovarian cancer (OC) consists of a combination of chemotherapy and cytoreductive surgery, but practice varies depending on the order of these 2 procedures: neoadjuvant chemotherapy followed by interval debulking surgery or primary cytoreduction followed by adjuvant chemotherapy. The aim of the work is to evaluate methods of treatment of OC of stages III, IV according to FIGO.The literature review includes publications in English from the PubMed, CochraneLibrary and Google Scholar databases on the use of neoadjuvant therapy and primary cytoreduction in late stages of OC (FIGO III–IV). 6 randomized controlled trials, 8 meta-analyses, 8 systematic reviews, 1 case report were identified. Data from publications were distributed according to the criteria for assessing the effectiveness of the treatment: overall and relapse-free survival, perioperative complications, quality of life of patients and the grade of cytoreduction.Neoadjuvant chemotherapy + interval debulking surgery is not inferior to primary debulking surgery + adjuvant chemotherapy in terms of survival outcomes in selected patients, but treatment with neoadjuvant chemotherapy + interval debulking surgery improves perioperative outcomes and optimal cytoreduction rates. It is needed to focus on finding optimal criteria for selecting patients in both groups in future studies of this issue. It is necessary to take into account X-ray, histological studies, the molecular subtype of the tumor, the patient’s condition, the qualifications of the surgical team, the drugs included in chemotherapy.
Chemotherapy for cervical cancer and contraception: discussion issues and clinical case
Authors: Ulrikh E. A. , Borshchevskiy V. G. , Zakharov I. S. , Bezmenko A. A. , Gayvoronskikh D. I. , Prichina A. V. , Saykina A. S. , Bairova A. K.
Published: May 2024

Cervical cancer occupies one of the leading places in the structure of oncological diseases of the Female Reproductive System. In the treatment of this pathology, along with the surgical method of treatment, chemotherapy and radiation therapy are used. According to clinical guidelines, in the presence of cervical cancer stages IIB–IIIA, it is allowed to carry out 2–4 cycles of neoadjuvant chemotherapy in order to create conditions for the possibility of performing extended hysterectomy according to Meigs. Pregnancy during chemotherapy is unique and extremely rare.The article presents a clinical case of pregnancy during chemotherapy (performed according to the scheme: taxanes and platinum-containing drugs) in a 27-year-old patient. According to the clinical picture and results of cervical biopsy, the diagnosis was made: invasive nonkeratinizing squamous cell carcinoma of the cervix IIB (cT2bNxM0) G2, right-sided parametric variant, nonspecific (with unspecified HPV status). Taking into account the presence of parametrial infiltration, the age of the patient, the oncological council prescribed from 2 to 4 cycles of chemotherapy according to the TC scheme (paclitaxel, carboplatin) with an interval assessment. After the second cycle of chemotherapy, an early pregnancy was diagnosed – a medical abortion was performed. Against the background of 3 cycles of chemotherapy, the conditions for surgical treatment were formed – surgical treatment was performed in the amount of extended hysterectomy according to Meigs (type III according to Piver/C2 Morrow) with transposition of the ovaries. The postoperative period was uneventful; the patient was discharged in a satisfactory condition.The described case of pregnancy on the background of chemotherapy is of scientific and practical interest, initiating a discussion on the need to counsel such patients regarding reliable contraception, taking into account the eligibility criteria, which will avoid undesirable outcomes during cancer treatment.
MORAL-ETHICAL AND PRAGMATIC COMPONENTS OF THE LEGAL NATURE OF THE RIGHT TO COMPROMISE IN THE CRIMINAL PROCESS OF UKRAINE
Authors:   Analytical department and the legal work of the Supreme Court, Sirotkina M.
Published: May 2024

The transformation that humanity is currently experiencing is leading to fundamental changes in every sphere of human existence. The changes dictated by the requirements of the time, the renaissance of the ideas of humanism as the ideological basis of society, leads to reforms in the field of criminal justice, changing and introducing new into the domestic criminal procedure legislation. The legislator is constantly looking for new effective ways for the state and society to respond to criminal offenses and combat crime, with the negative consequences of the ineffectiveness of only traditional prosecution and punishment. An effective way to resolve a conflict that has arisen as a result of a crime may be to use compromise procedures in criminal proceedings, along with traditional ones. Despite the sufficient number of scientific studies of certain criminal procedural mechanisms of compromise or conciliatory nature, it should be noted the lack of scientific research on the right to compromise in the criminal process of Ukraine and its implementation, the study of its legal nature through the prism of morality and pragmatism. the right to compromise in the criminal process of Ukraine». The aim of the article is to study the influence of moral and ethical components and pragmatic approach in the compromise solution of criminal conflict between the state, the perpetrator and the victim of the legal nature of the right to compromise in the criminal process of Ukraine and the author’s definition of «right to compromise». in the criminal process of Ukraine «. The results of scientific research by the author of this issue were the conclusion that morality, in some cases, prevails over the imperative of legal liability for what is done in case of guilty remorse, evaluation and willingness to voluntarily make amends to the victim, compensating the latter. . A clear example of this is the mechanisms for exercising the right to compromise in criminal proceedings, which are enshrined in law and at the legislative level. After analyzing the moral and ethical and pragmatic components of the legal nature of the right to compromise in criminal proceedings, the author’s definition of the right to compromise in criminal proceedings in Ukraine – the right to receive values, benefits of a regenerative nature, which corresponds to the duty of the perpetrator both for the victim and for society, in order to restore the disturbed public peace, security and law and order.
THE CONCEPT OF CASE LAW OF THE EUROPEAN COURT OF HUMAN RIGHTS AS A SOURCE OF CRIMINAL PROCEDURAL LAW OF UKRAINE
Authors:   Yuriy Fedkovych Chernivtsi National University, Chernivtsi, Ukraine, Kalancha I.G.
Published: May 2024

The article deals with the ways of regarding the case law of the European Court of Human Rights as a source of criminal procedural law of Ukraine, which is relevant both in terms of the criminal procedure as a science and for the practice of law enforcement. The purpose of the article is to formulate the concept of the case law of the European Court of Human Rights as a source of criminal procedural law of Ukraine. The paper justifies the opinion that the case law of the European Court of Human Rights is developed and based on the decisions of the European Court of Human Rights and the European Commission of Human Rights, regardless of the country in which they were adopted (i. e. has a polyterritorial jurisdiction over states being the participants of the Convention). The article proves that the case law of the European Court of Human Rights is draws upon the decisions made by the European Court of Human Rights and the European Commission of Human Rights regardless of the time of adoption, i. e. it includes the decisions adopted before Ukraine ratified the Convention for the Protection of Human Rights and Fundamental Freedoms. The author points out the appropriateness of classifying decisions that have acquired the status of final as «case law of the European Court of Human Rights». It is also mentioned that there is a need to include final decisions in the case (as the matter of fact), which have a decisive nature and contain a legal position in this case, into the scope of the category «case law of the European Court of Human Rights». Moreover, the article substantiates the necessity to include the decisions adopted by the European Court of Human Rights in full, i. e. not only the set forth legal positions, into the category of «case law of the European Court of Human Rights». Following the results of the study, the case law of the European Court of Human Rights as a source of criminal procedural law of Ukraine is defined as a set of decisions adopted by the European Court of Human Rights and the European Commission of Human Rights, which have entered into force and contain legal policies which either clarify or specify the provisions of the Convention as for the Protection of Human Rights and Fundamental Freedoms and relate to human and citizen’s rights and freedoms.
O que resta de Nietzsche ou Narizinho no espelho
Authors: Burnett Henry
Published: May 2024

O artigo procura discutir as principais linhas de influência do pensamento de Nietzsche na formação intelectual de Monteiro Lobato. Para isso, utiliza a troca epistolar do autor com Godofredo Rangel, reunida em A barca de Gleyre. A intenção é demonstrar o lugar destacado que Nietzsche ocupa entre as referências do escritor. Em várias cartas, a interpretação de Monteiro Lobato é claramente equivocada, em outras, alinhada ao que havia de mais progressista. Ao cotejar depoimentos que cobrem quase 50 anos de atividade intelectual, a conclusão é que Monteiro Lobato considerava Nietzsche um modelo de liberdade e independência moral. Até o fim, Lobato permaneceu irmanado ao “seu filósofo”, como se referiu a Nietzsche mais de uma vez.
Legal Engineering in the Legal Ecosystem of the Digital Economy
Authors: Spasowska-Czarny Hanna
Published: May 2024

In the digital economy, the use of artificial intelligence is inevitable, including by lawyers. While there is a perception that artificial intelligence will not fundamentally change the practice of law, and that the legal profession requires specialised skills and making judgments in a way that only humans do, the use of technology in the legal sector is and will continue to become more prevalent. While not every problem can be solved by technology, there are fewer and fewer solutions that will not be supported by it in some way. This will increase the role of legal engineers – they will build the future of law, which can be imagined as a collaboration between all members of an organisation, including those with a legal background and those with experience in other fields. The diversity of perspectives encourages innovative thinking, the creation of more efficient service delivery models, and the satisfaction of both service providers and service recipients, while work automation minimises risk and reduces the number of errors by ensuring that the same rules are followed every time. Many lawyers have accepted that technology has and will continue to play a big role in their work, although not all are well equipped to use it. They need new skills, primarily in management, project delivery, finance, marketing, mediation and negotiation, as well as modern technology.