bluuebunny/crossref_metadata_2025 huggingface dataset:
Urinary syndrome in patients with adrenal endocrine hypertension
Authors: Gazymov M. M. , Gazymova M. Kh.
Published: March 2022

Symptomatic hypertension is often regarded by doctors as a kidney disease and without proper critical evaluation of the identified changes in urine diagnose chronic pyelonephritis, which delays the establishment of the true nature of the process for a long time. Timely diagnosis is also complicated by the fact that endocrine diseases, such as Conn's syndrome, pheochromocytoma, occur without any external manifestations of endocrinopathy. Such patients are not examined by endocrinologists, so the diagnosis is usually made (not in all patients) by general practitioners, urologists, surgeons. The aim of this work was to determine the frequency and peculiarities of urinary syndrome (proteinuria, microhematuria, leukocyturia), renal dysfunctions in adrenal hypertension before and after surgical treatment of patients.
Central analgesia and hypothermia in cardiac surgery
Authors: Valitov S. A. , Zhavoronkov V. F. , Nurgaleeva R. N. , Yusupov F. S.
Published: March 2022

In our country, cold protection of the brain from hypoxia during operations on the heart and great vessels has been widely used. Significant contribution to the development of the method was made by domestic anesthesiologists and intensive care specialists. The issues of increasing the efficiency of general hypothermic protection during cardiac surgery continue to be in the focus of attention of researchers at present time as well.
Prevention of hemostasis disorders in gestosis
Authors: Fedorova Z. D. , Repina M. A. , Katsadze Yu. L. , Krasovskaya G. A. , Konycheva E. A. , Sumskaya G. F. , Mazepova N. I. , Nikolaeva N. K. , Rudenko T. T.
Published: March 2022

The high incidence of thromboembolic and hemorrhagic complications during pregnancy and childbirth causes the interest of many researchers in the study of the hemostatic system and blood rheological properties during these periods. Normal pregnancy is characterized by hypercoagulation against the background of decreased blood fibrinolytic activity. Accelerated generation of thrombin with increased levels of -thromboglobulin in the plasma and reduced platelet lifespan is, according to some authors, a phylogenetically determined body adaptation in preparation for childbirth.
Pathopsychological assessment of the nosological independence of neuroses
Authors: Mendelevich V. D.
Published: March 2022

In clinical neurology today, there is a revision of the principal positions, which casts doubt on the nosological essence of neuroses. The issues of differential diagnostic criteria of neuroses, boundaries of neuroses and neurotic personality development, accentuation of character traits and decompensation of psychopathies remain rather debatable in psychiatry up to now. Questions of clinical differentiation of psychologically adequate, preclinical, neurotic and psychopathic reactions to frustration are poorly studied. As a consequence, the importance of pathopsychological studies of borderline neuropsychiatric disorders, the study of patients' self-esteem and self-awareness, and the analysis of compensation mechanisms and protective measures that contribute to the prevention of neurosis is growing.
Use of vasodilators in the complex treatment of patients with coronary heart disease and congestive heart failure
Authors: Zharov E. I. , Buzanova M. A. , Vertkin A. L.
Published: March 2022

Congestive heart failure continues to be a very common complication of coronary heart disease, often leading to fatal outcome. Rational treatment of this complication requires understanding of its underlying pathophysiological mechanisms. Patients with congestive heart failure have characteristic hemodynamic abnormalities.
Effect of combined treatment of hypertension with cristepine and obzidan on hemodynamics and parameters of the renin-aldosterone system
Authors: Leviashvili B. I.
Published: March 2022

The aim of the present study was to study the effect of combined therapy with -blocker obzidan (40-80 mg per day) and cristepine (2-3 tablets per day) on central hemodynamics and indices of renin activity and blood plasma aldosterone level. We observed 67 patients with grade II hypertension aged 35 to 60 years. Hypertension was diagnosed by excluding all possible forms of symptomatic arterial hypertension. Its cerebral manifestations - headaches, dizziness, darkening of the eyes, nausea - dominated in the disease clinic.
Dynamics of cellular and humoral immunity parameters in children under the influence of specific immunotherapy with food allergens
Authors: Potemkina A. M.
Published: March 2022

In recent years, our country has devoted considerable attention to the study of food allergies in children, which in many respects remains understudied; in particular, ways to improve the effectiveness of specific treatment are being sought. Attempts to use specific hypersensitization with food allergens in children and adults by oral, inhalation, subcutaneous and rectal methods have not yielded the desired results. The sublingual method, successfully tested for the first time on several adult patients, proved to be more promising. The efficacy of this method used in children with food allergies was 70-80%.
Magnesium metabolism disorder in rickets-like diseases
Authors: Kankasova M. N. , Myakisheva L. S.
Published: March 2022

Rickets-like diseases are inherited metabolic disorders. The most common forms of these diseases are vitamin-E-dependent rickets, Debret de Tony-Fanconi disease, and vitamin-D-resistant rickets. Their differential diagnosis is still very difficult because the clinical and radiological picture of these forms is very similar. All forms of rickets-like diseases are characterized by significant metabolic disorders and primarily phosphorus-calcium metabolism. A large role in metabolic processes in the body plays magnesium as an activator of many enzymes, in particular alkaline phosphatase and pyrophosphatase, directly related to the process of mineralization of bone tissue. A number of authors note the close relationship of magnesium metabolism with phosphorus-calcium metabolism. However, magnesium metabolism in rickets-like diseases has been insufficiently studied; the magnesium level in the blood was determined only in individual patients.
Emergency dental care and general anesthesia in an outpatient clinic setting
Authors: Dzamukov A. D. , Bitazis Sh. D. , Rafikova S. Kh. , Antonovich A. M.
Published: March 2022

We treated 300 patients under anesthesia, 173 of whom were treated for emergencies. The overwhelming majority of patients had multiple oral pathologies, however, when establishing emergency indications for intervention we proceeded from the presence of a certain local process: pulpitis, periodontitis, osteomyelitis, phlegmons, etc.
A case of marbling disease
Authors: Orlova S. N. , Romanova N. A.
Published: March 2022

Marmara disease is a congenital dysplastic disease characterized by diffuse osteosclerosis of almost the entire bone skeleton. Since the initial description of the disease based on the radiological picture by Albers-Schenberg in 1904, about 200 cases are known in the world literature.
Development of new ways of operative interventions on the submucosal membranes of the stomach
Authors: Tukhbatullin M. G.
Published: March 2022

At the present time in the treatment of peptic ulcer disease of the stomach and duodenum the pyloroanthral gastric demucosalization is applied. Reduction of secret-producing function of the stomach is also achieved in case of small curvature zone demucosalization with subsequent suturing of mucosal defect. Although subtotal mucosectomy is accompanied by persistent decrease in hydrochloric acid secretion, however it has not found clinical application due to its traumatic and unphysiological character. It should be noted that gastric demucosalization is not without its negative sides: it is not aseptic, because the lumen of the stomach is opened; it is associated with difficulties of suturing the gastric mucosa; there is also a risk of bleeding from the submucosa in extensive mucosectomies. The aim of our research was the experimental development of new methods of surgical interventions on the stomach by resection of its submucous-mucous membranes with preservation of serous-muscular membranes, pyloric jejunum and structures innervating them.
On the treatment of some intra-articular injuries of the knee joint
Authors: Kotelnikov G. P.
Published: March 2022

From 1970 to 1985, 414 patients with ligament-capsular apparatus ruptures of the knee joint were treated in the Clinic of Traumatology, Orthopedics and Military Field Surgery. Autotissues were used as plastic material in the majority of them, and preserved tendons and lavsan were used when indicated. The clinic developed and successfully applied minimally traumatic methods of plasty of injuries of the anterior cruciate and internal collateral ligaments of the knee joint, combined with rupture of the internal meniscus (Turner triad).
Peculiarities of the formation of external respiratory function and acid-base status in premature infants
Authors: Saidova M. V. , Imamutdinova A. S.
Published: March 2022

The immaturity of a number of functional systems in premature infants has a significant impact on adaptation to the conditions of extrauterine existence. First of all, it concerns the external respiratory system, which in premature infants has clear signs of immaturity. The body even of a preterm infant at birth is for some time under conditions of reduced gas exchange and moderate metabolic acidosis, but this period is short - gas exchange is quickly normalized.
Effect of premature rupture of amniotic fluid on the development of newborn external respiration
Authors: Yaroslavsky V. K. , Malyarchuk V. V.
Published: March 2022

The status of the intrauterine fetus in 80 pregnant women with a full-term pregnancy and premature miscarriage was studied, as well as the respiratory adaptation of the babies born. The duration of water-free period in Group 1 (25) women in labor was 6-12 h, in Group 2 (35), 12-20 h, and in Group 3 (20), more than 20 h. Complications occurred in 23 women in labor (weak labor activity, fetal hypoxia), which required the use of abdominal forceps in 4 of them and cesarean section in 3. Labor induction was used in 43 women.
Congress of pediatric dentists of the GDR
Authors: Saifullina H. M.
Published: March 2022

The National Congress of Pediatric Dentists of the GDR was attended by over 500 specialists from the GDR and representatives of the USSR, Czechoslovakia, the People's Republic of Poland, the People's Republic of Bulgaria, the Federal Republic of Germany, the SFRY, Finland, and Switzerland. The Soviet delegation was represented by Prof. T.F. Vinogradova (Moscow), Prof. Kh.M. Sayfullina (Kazan), doc. R. J. Tsare (Riga), Dr. O. P. Maksimova and Dr. O. A. Prokusheva (Moscow).
To the pathogenesis of cerebral circulation disorders in young women
Authors: Kakhovsky E. A. , Buraeva N. V.
Published: March 2022

In recent years, the dependence of vascular disease on age and sex has been widely discussed in the literature. Disturbance of hormonal activity of endocrine glands plays an important role in the development of circulatory pathology.
Indications for bladder blind suture in suprapubic transurethral adenomectomy
Authors: Sitdykov E. N. , Basiashvili T. G.
Published: March 2022

Suprapubic transurethral adenomectomy is the most common method of surgical treatment of patients with prostatic adenoma. Some authors recommend to end the operation with the primary bladder blind suture with a short-term urethral drainage; others, being afraid of postoperative inflammatory complications in the upper urinary tract and kidneys, genitals, as well as secondary bleeding from the prostatic adenoma bed, prefer to perform temporary urine drainage additionally through the suprapubic bladder stoma.
Enzyme immunoassay method to assess hemostasis system activity in patients in the acute period of myocardial infarction
Authors: Soloviev A. V. , Ermolin G. A. , Dikov M. M. , Ignashenkova G. A. , Efremov E. E.
Published: March 2022

According to modern concepts, intravascular coagulation of blood is of dominant importance in the pathogenesis of myocardial infarction. Development of DIC syndrome in patients with acute myocardial infarction is associated with the entry of a significant amount of procoagulant material into the bloodstream, which leads to a disorder in the hemostasis system with formation of microthrombi in arterioles, capillaries and venules of various organs with or without violation of their function. At the same time the fibrinolytic system is activated, which is accompanied by the cleavage of fibrin and fibrinogen and the appearance in the blood of products of their degradation (PDF).
Value of antithrombotic therapy in patients with coronary heart disease
Authors: Vogralik V. G. , Saltseva M. T. , Amineva N. V. , Klemenov V. I.
Published: March 2022

Numerous studies have shown that intravascular thrombosis is one of the main causes of death in patients with coronary heart disease. Therefore, the issues of prevention of thromboembolic complications and development of the tactics of differentiated antithrombotic therapy in coronary heart disease, including chronic forms of the disease, are extremely relevant.
Role of free-radical oxidation in the pathology of newborns and infants
Authors: Pikuza O. I. , Gabitova N. Kh. , Khairullina N. N.
Published: March 2022

The processes of free-radical oxidation of lipids are considered to be the fundamental molecular mechanism of biological membrane damage. At the present stage, significant data have been accumulated on the activity of lipid peroxidation processes in acute pathology in children.
Activation of factor XII clotting
Authors: Baishev I. M.
Published: March 2022

The origins of modern concepts of contact activation of blood clotting go back to the middle of the last century. In 1862, Lister drew attention to the fact that sheep's blood collected in a rubber test tube remained flowing significantly longer than that placed in a glass or ceramic cup. It was also observed that blood clotting was slower in tubes coated inside with oil or Vaseline. As a result, it was believed that blood-wetted contact surfaces (glass, etc.) promote rapid coagulation of liquid blood or plasma, while non-wetted (like paraffin), on the contrary, slow the clotting process.
Tissue thromboplastin
Authors: Baikeev R. F.
Published: March 2022

The appearance of tissue thromboplastin (factor III, tissue factor) in the bloodstream leads to one of the most dangerous non-specific disorders of hemocoagulation - disseminated intravascular clotting (DIC). Although the components of the thromboplastin reaction are known, the molecular organization of tissue thromboplastin to the extent necessary to understand the initiation of the external pathway of the blood coagulation system has not been detailed to date.
Experience of surgical interventions in gynecological patients of elderly and old age
Authors: Malkov Ya. Yu. , Kazakova E. V.
Published: March 2022

We analyzed surgical outcomes in 235 women aged 50 to 81 years operated on for uterine fibroids, ovarian cystomas (49), endometrial cancer (30), uterine prolapse and vaginal wall prolapse (25), preinvasive cervical cancer combined with myoma and adenomatosis (3), uterine tube cancer (1).
Microcirculation and pulmonary diffusion capacity in patients with systemic scleroderma and chronic nonspecific lung diseases
Authors: Amirov N. B.
Published: March 2022

We studied microcirculation and pulmonary diffusion capacity in 108 patients with systemic scleroderma (29) and chronic nonspecific lung diseases (79). There were 53 men and 55 women. The control group consisted of 33 healthy individuals-15 men and 18 women.
Criteria for correction of circulating blood volume in patients with severe mechanical injuries
Authors: Krylov V. E.
Published: March 2022

Patients with mechanical injuries have more or less pronounced changes in circulating blood volume, which, of course, affects blood circulation and acid-base status. Therefore, one of the primary objectives of resuscitation aid is normalization of circulating blood volume. The amount and rate of infusion should be determined not by integral indicators of blood pressure and pulse, i.e. empirically, but individually for each patient.
Provision of healthy children with vitamins in the winter-spring period
Authors: Zemlyakova E. I. , Mustafina G. M.
Published: March 2022

Provision of vitamins is one of the important factors determining the state of children's health, since their deficiency leads to functional disorders of a number of organs and systems, reduces the body's resistance. Isolated deficiency of a single vitamin is rare, much more often there is a deficiency of several vitamins.
Medical and social aspects of emergency medical care for children
Authors: Zakirova R. A. , Belogorskaya M. V.
Published: March 2022

The aim of the study was to investigate the medical and social aspects of children's ambulance attendance by examining each case of a call. The results are intended for rational organization of children's ambulance service, determining the profile and equipment of the brigades. We analyzed 331 pediatric ambulance calls to children under the age of 7 years.
Myocardial contractile function and acid-base balance in trauma patients treated by the Ilizarov method under peridural anesthesia
Authors: Zakirov E. Kh.
Published: March 2022

Peridural anesthesia as a method of anesthesia continues to attract attention because it has no pathological effect on the functions of vital organs, except for rare cases of severe hypotension. There are controversial opinions regarding the effect of peridural anesthesia on cardiodynamics. Some authors believe that peridural blockade reduces the tonic action of sympathetic nerves, resulting in bradycardia, decreased myocardial contractile function with depressed cardiovascular system. Others argue that during peridural anesthesia there are no significant changes in intracardiac hemodynamics. According to others, moderate concentrations of anesthetic penetrating into the circulating blood increase cardiac output and slightly increase BP.
Bone grafting of limb bone defects after tumor removal
Authors: Akberdina D. L. , Takhavieva D. G.
Published: March 2022

One of the indications for bone grafting is a bone defect resulting from the removal of bone tumors. This report describes the experience of bone grafting in 161 patients who underwent bone resection due to tumors and tumor-like processes of limb bones (Table 1). According to their age the patients were distributed as follows: 17 to 20 years old - 39 patients, 21 to 30 - 51, 31 to 40 - 46, 41 to 50 - 14, over 50 - 11.
Acute adhesive intestinal obstruction - retrospective analysis
Authors: Salikhov I. A. , Krasilnikov D. M. , Fedorov V. V. , Karpukhin O. Yu.
Published: March 2022

206 patients with various forms of intestinal obstruction have been treated in our clinic during the last 5 years. In 78 (37,9%) patients intestinal obstruction causes were adhesions, in 46 (22,3%) - pinch hernia, in 40 (19,4%) - obturation, in 15 (7,3%) - volvulus, in 7 (3,4%) - spastic ileus, in 3 (1,5%) - paralytic ileus, in 3 (1,5%) - intussusception, in 14 (6,8%) - other causes. Out of 206 patients 39 died. Overall lethality in intestinal obstruction was 18.9%.
Fibronectin content and cellular composition of peritoneal exudate in peritonitis
Authors: Kochnev O. S. , Veliyev N. A. , Harrasov A. F. , Litvinov R. I. , Zinkevich O. D.
Published: March 2022

Without denying the great importance of general body resistance in peritonitis, recently, many researchers tend to consider peritonitis as a kind of local inflammation with new pathogenetic and therapeutic concepts derived from this approach. It is known that the course and outcome of microbial inflammation are largely determined by the severity of local antimicrobial protection, which is primarily determined by antibacterial properties of the inflammatory exudate. Among the reactions of bacteria neutralization, the leading role is assigned to phagocytosis, which occurs with the participation of neutrophils and macrophages. The efficiency of phagocytosis, in turn, depends, first, on the number and quality (i.e., functional state) of the phagocytic cells and, second, on the activity of humoral factors of phagocytosis, called opsonins.
Leukocyte intoxication index of peritoneal exudate as a diagnostic test of postoperative peritonitis
Authors: Biryaltsev V. N. , Veliyev N. A. , Kim Yu. Kh.
Published: March 2022

The problem of diagnostics and treatment of postoperative peritonitis and various intra-abdominal purulent complications is still one of the most urgent problems of emergency surgery. The lethality from peritonitis reaches 20-40% [1, 4]. Difficulties of diagnosing postoperative peritonitis are due to the layering of symptoms of the complication on the manifestations of postoperative condition and intensive care [5, 7]. Therefore, postoperative peritonitis is diagnosed at a late stage, which leads to delayed reoperations, and ultimately, to increased mortality.
Erythrocyte membrane permeability in diabetic patients
Authors: Maksimova O. V.
Published: March 2022

The state of cellular homeostasis in diabetic patients was assessed by the permeability of erythrocyte membranes, which can serve as an indicator of functional disorders of the vascular wall. It was found that the value of cytoplasmic membrane permeability depends largely on the variations in the ratio of cholesterol and phospholipids. An absolute or relative increase in membrane cholesterol content is accompanied by stabilization of cellular structures, which, in turn, leads to a decrease in permeability to non-electrolytes and ions and changes in the activity of membrane-bound enzymes.
Mechanisms of destabilization of erythrocyte energy metabolism in the acute period of myocardial infarction
Authors: Golovacheva T. V. , Zakharova N. B.
Published: March 2022

The aim of the study was to assess the role of the main branches of the polyenzyme system of erythrocyte glycolysis in the development of their energy-synthesizing insufficiency in the acute period of myocardial infarction.
Treatment of patients with paranoid schizophrenia with depressive states
Authors: Omorokov B. M. , Hamburg A. L. , Aronovich A. G. , Kotelkevich Yu. N.
Published: March 2022

In the treatment of schizophrenic patients with complex depressive-paranoid states, various combinations of neuroleptics and antidepressants are widespread, but the tactics of their use have not yet been sufficiently developed.We compared the regression of psychopathological symptoms and the results of therapy in three clinically homogeneous groups of schizophrenia patients with different order of administration of thymoneurolepsy components.
Sanitary and epidemiological analysis of the decrease in the incidence of typhoid fever in the Tatar ASSR during 30 years (1955-1985)
Authors: Pochkin Yu. N. , Morozov V. V. , Valeev A. L.
Published: March 2022

From 1955 to 1985 in both urban and rural settlements of the Tatar ASSR there were positive changes in the sanitary conditions of the population: improvement of the sanitary condition of water supply sources, increase in the number of water pipes (see figure), reduction of the share of decentralized water supply sources, improvement of laboratory control of water supply sources and drinking water, and increase in water consumption of the population.
Prospects of reflexotherapy in the dispensary examination of neurological patients
Authors: Ivanichev G. A.
Published: March 2022

It is well known that the existing systems for the clinical examination of neurological patients have a number of disadvantages. The main ones are labor-intensive and cumbersome both diagnostic, including preventive examination, and therapeutic measures. The division of patients into the observation groups recommended by official guidelines allowed to put a significant emphasis on preventive treatment of patients with severe organic brain lesions, but this only partially solved the problem. A large part of the examinees, conventionally assigned to risk groups and practically healthy individuals, fall out of the neurologist's sight for a long time due to their workload both in the outpatient clinic and in the inpatient clinic.
Acupuncture in obstetrics
Authors: Kozlov L. A. , Dobronetsky V. S. , Polyakova N. S.
Published: March 2022

The attention of obstetricians and gynecologists to the method of reflexotherapy is attracted by the possibility of reducing the pharmacological load on the body of the pregnant woman and the fetus, the absence of unwanted side effects when used properly. Reflexotherapy can also be the method of choice in the presence of intolerance to a number of pharmacological compounds. Reflexotherapy improves protective properties of organism, has normalizing effect on tone and reactivity of vegetative section of nervous system, normalizes activity of endocrine glands, in particular, sex glands, regulates tone of muscles. It is proved that this method significantly influences hypothalamic-pituitary-adrenal system of the organism.
Surgical treatment of tuberculous spondylitis in the TB Dispensary
Authors: Usmanov I. V.
Published: March 2022

Treatment of tuberculous spondylitis in TB dispensaries remains a difficult task. Conservative treatment of spinal tuberculosis is effective only at the initial stage of the lesion. However, in recent years, focal forms of TB occur less frequently among newly diagnosed patients, and neglected and complicated forms of this disease, on the contrary, are more frequent, which is associated with diagnostic errors. In such cases, conservative treatment and antibacterial agents are ineffective; they are used only in the period of preoperative preparation and especially after surgery.
Method for assessing the functional state of the spine
Authors: Ogienko F. F. , Torchinov I. A.
Published: March 2022

Our proposed method for assessing the functional state of the spine (Priority License No. 3844463/14-9766) consists of measuring the anterior height of any intervertebral disc (hp) at maximum extension and correlating it with the anterior height (he) of the same disc at maximum flexion on lateral radiographs of the spine.
Processing echocardiography results with microcalculators
Authors: Dzyak G. V. , Loginov S. V. , Reiderman Yu. I.
Published: March 2022

Ultrasound diagnostics in cardiology is associated with the necessity of time-consuming calculations of geometric parameters of the left ventricle. These calculations can be considerably reduced by the doctor using commercially available unfunded microcalculators, such as MK-56. Limited memory capacity of these microcalculators (99 commands) predetermined the creation of a library of self-applied programs.
The importance of prognostic modeling based on the diagnosis of pre-pathology for the dispensary
Authors: Mizin V. T.
Published: March 2022

The presence of lowmanifest forms of diseases, steadily compensated pathological conditions, extreme environmental influences, negative influences of industrial and domestic conditions, heredity, bad habits cause the necessity to improve the health of almost every person. The purpose of the clinical examination is to detect early pathological changes which do not affect people's health for a long period of time and which, therefore, are not considered to be ill. The transition from health to disease is accompanied by the development of preclinical borderline conditions, referred to as prenosological.
Study of some ventilation parameters in patients with lung and heart diseases using a domestic volumospirograph
Authors: Fazulzyanov A. A. , Zhungin P. D. , Andreev V. M.
Published: March 2022

The most objective and sensitive method of bronchial obstruction diagnosis is determination of maximal expiratory flow at different levels of bronchial tree. Despite the lack of clear boundaries of the norm, the flow indices according to spirography allow early diagnosis of bronchial permeability disorders, which facilitates the diagnosis of obstructive bronchitis and bronchial asthma.
Effect of intraoperative hemodilution on lung and blood respiratory function after abdominal delivery
Authors: Serov V. N. , Zaznova G. A. , Zharov E. V. , Minaev I. V. , Ustenko O. V.
Published: March 2022

Caesarean section surgery is always accompanied by significant blood loss, the value of which varies quite widely - on average, from 800 to 900 ml. Tactics to compensate blood loss during this operation is constantly debated in the press, and there are completely polar points of view - from the recognition of the need to compensate blood loss "drop by drop" and even create hypervolemia to the complete rejection of transfusion therapy during abdominal delivery.
Expert evaluation of patients' ability to work after cystectomy with bladder replacement by intestinal grafts
Authors: Sitdykova M. E. , Zubkov A. Yu.
Published: March 2022

251 cystectomies for bladder cancer with different methods of urine diversion were performed in the urology clinic. 171 patients underwent urine diversion into an isolated bowel segment with restoration of independent urethral urination. The stage of the cancer process in them was distributed according to the international classification as follows: T2 - in 37 patients, T3 - in 121, T4 - in 13 patients.
A case of hereditary angioedema
Authors: Burnasheva R. Kh. , Fassakhov R. S. , Khramov V. V. , Voitsekhovich G. S. , Reisman S. M.
Published: March 2022

Allergic edema is one of the most common clinical manifestations of hypersensitivity reactions. The characteristic clinic, a clear association with a specific allergen, the data of allergological examination of such patients usually leave no doubt about the diagnosis. However, such forms of edema occur, which resemble Quincke's edema, but have other mechanisms of development unrelated to allergy, in particular hereditary angioedema categorized by A. D. Ado into a group of pseudoallergic reactions. Despite its relative rarity, this disease has a very malignant course and, if not diagnosed and treated in time, can lead to an adverse outcome.
Enzymatic diagnosis of coronary heart disease
Authors: Latfullin I. A. , Sviridkina L. P. , Aglullina E. I. , Ivanova S. V. , Izosimova L. A. , Duleeva T. V.
Published: March 2022

The importance of enzyme diagnostics of myocardial infarction is currently beyond doubt. Determination of asparagine and alanine transaminases activity has been replaced by the study of more sensitive so-called "cardiospecific" enzymes: creatine phosphokinase, lactate dehydrogenase and their isoenzymes. LDH isoenzyme1 has special specificity to the heart muscle, the content of which is studied by hydroxybutyrate dehydrogenase activity (-HBDH). However, the patterns of changes in the activity of this enzyme in various forms of ischemic heart disease remain insufficiently studied. The content of -glutamyl transpeptidase enzyme in cardiac muscle is insignificant; however, there are reports in the literature about increased activity of this enzyme in the acute period of myocardial infarction. The degree of hyperenzymemia in acute myocardial infarction usually correlates with the size of ischemic necrosis focus, so a significant increase in enzyme activity is found in those forms of the disease, which proceed with a clear clinical picture and are accompanied by typical changes on ECG. Meanwhile, clinicians still face difficulties in differential diagnosis of such variants of ischemic heart disease as various forms of angina pectoris, small focal myocardial necrosis, recurrent myocardial infarctions and cardialgia of different genesis. The similarity of their clinical symptomatology and unclear ECG criteria make us return to the analysis of enzyme activity changes in various forms of coronary heart disease.
Clinic and outcomes of viral hepatitis A and B with parenteral transmission
Authors: Bashirova D. K. , Enaleeva D. Sh. , Fatkulov M. S. , Sadekova Ya. Kh.
Published: March 2022

Viral hepatitis A or B is one of the least studied. Its incidence varies in Europe from 14 to 40%. In Moscow, according to the Institute of Virology named after D.I. Ivanovsky of the USSR Academy of Medical Sciences, it accounts for 15-20%. The term "viral hepatitis neither A nor B" is usually used to refer to a disease caused by an agent having no serological similarity with the causative agent of viral hepatitis A or B. However, all nosological forms of viral hepatitis are characterized by similar clinical symptoms of biochemical changes, which makes their identification difficult.
Plasma fibronectin and hemocoagulation changes in acute dysentery
Authors: Bulatova N. A. , Odisharia M. S.
Published: March 2022

We studied the dynamics of blood plasma fibronectin level and hemostasis indices in shigellosis patients. We followed up 80 patients (60 men, 20 women) mainly aged 20 to 40 years with shigellosis infection. Bacteriological diagnosis was confirmed in 56.6% of cases. The predominant isolation of Shigella Flexnera was noted. All patients were divided into three groups depending on the severity of the disease. The 1st group (16 patients) included patients with a mild form of the disease; the 2nd group (52 patients) included patients with a moderate form of the disease; the 3rd group (12 patients) included patients with a severe form of the disease.
Use of hypertonic urea solution in the treatment of pleural empyema
Authors: Strelkov G. N. , Korepanov A. M.
Published: March 2022

Our experience covers 8 cases, all of them clinically severe. Prior to that all patients were treated without effect in different medical institutions. In 2 patients a pleural empyema was complicated by an extensive soft tissue phlegmon caused by medical manipulations (installation of a Bhlau drain). After suction of purulent contents through a puncture needle, 40 to 60 ml of 30% urea solution was injected into the pleural cavity. The same procedure was repeated 4-6 times in 1-2 days. Phlegmons were opened with lombard incisions. Dressings were done daily using the same 30% urea solution. All empyemas were sanitized to a dry pleural cavity. Phlegmons also healed without leaving deep scars.
Effect of physical activity and inhalation of berotec on ventilation and hemodynamics in patients with pulmonary tuberculosis
Authors: Vizel A. A.
Published: March 2022

Physical activity tolerance in pulmonary tuberculosis is determined to a greater extent by the state of pulmonary ventilation and to a lesser extent by pulmonary gas exchange, the latter being partially compensated by hemodynamic factors. The appearance and severity of dyspnea in such patients are largely associated with obstructive disorders at the level of medium and small bronchi, which determines the relevance of correction of these disorders. Among bronchodilators of adrenomimetic type of action one of the most effective is Berotec, which not only improves bronchial permeability, but also increases mucociliary clearance.
Errors in the diagnosis of tuberculous spondylitis
Authors: Usmanov I. V.
Published: March 2022

From 1983 to 1986, 42 patients (25 men and 17 women) with tuberculous spondylitis were treated in the department of bone and joint tuberculosis at the Almetyevsk Anti-Tuberculosis Dispensary. Two patients were under the age of 18, 15 patients were between 19 and 40, 17 patients were between 41 and 60, and 8 patients were older than 61. These data do not agree with the idea that children are predominantly affected by this disease. We attribute tuberculous spondylitis detected in our patients at an older and elderly age to the exacerbation of latent infection suppressed in their childhood.
Determination of β2-microglobulin in urine and blood of bladder cancer patients
Authors: Belyaev A. R. , Sitdykova M. E. , Zubkov A. Yu. , Begicheva E. V.
Published: March 2022

The functional state of the kidneys and upper urinary tract often determines the type and nature of surgical treatment for bladder cancer. One of the tests for renal dysfunction is the determination of the low molecular weight protein 2-microglobulin in the blood and urine. Protein concentrations in the blood and urine are altered in a number of inflammatory, autoimmune, infectious, and oncological diseases.
Influence of maternal health on the occurrence of dental caries in children
Authors: Galiullin A. N. , Abdyushev Sh. Ya. , Vinokurova M. A. , Sadykova R. A.
Published: March 2022

The aim of this study was to comprehensively assess the influence of the main biomedical factors (diseases suffered during pregnancy, extragenital diseases, pregnancy complications, prematurity, skewness, etc.) on the level of dental morbidity in children for the development of primary prevention measures and improvement of dental care for the population. The program included a detailed study of maternal health, the course of pregnancy and childbirth, the child's health, physical development, and nutrition. In accordance with this program, a research map of socio-hygienic, medico-biological and other factors influencing dental morbidity in children was developed. A total of 2,274 families were examined, with 97 to 205 families in each age group of children.
Ways to reduce the incidence of pneumonia in children
Authors: Belogorskaya E. V. , Kuznetsova L. A.
Published: March 2022

Respiratory diseases occupy the first place in the structure of childhood diseases: acute respiratory infections, bronchitis, pneumonia. After perinatal pathology, pneumonia is one of the main causes of infant mortality.
Functional status of pituitary-ovarian system in patients with severe forms of septic diseases
Authors: Shinkareva L. F. , Tetelyutina F. K. , Pimenova L. I. , Tolstolutskaya E. A.
Published: March 2022

Fifty-nine women were examined; 18 of them had pyosalpinx, 38 had pelveoperitonitis, and 3 had parametritis. The control group included 10 healthy women. The patients' age ranged from 22 to 42 years, averaging 31.71.8 years, and 33.70.6 years in the healthy women. When studying the anamnesis, it was established that all the women had infectious diseases in childhood. Eight patients had appendectomy, four had pneumonia, two had craniocerebral trauma, one had dysentery, three had thyroid disease. Of gynecological diseases, we should note frequent inflammatory diseases of the uterus and uterine appendages, colpitis, and cervical erosions (in 42 cases).
Operational risk in abdominal surgery
Authors: Gantsev Sh. Kh.
Published: March 2022

There is a concept of "surgical risk" for judging the degree of surgical danger. The changes occurring in the organism under the influence of surgical trauma are determined, on the one hand, by the traumatic nature of the operation, and, on the other hand, by the reliability of homeostasis regulation systems. Traumaticity is a variety of mechanical, chemical and other impacts on the body of the operated, which are directly proportional to the duration of surgical interventions, its scale and exposure areas. The reliability of homeostasis regulation systems consists of a large number of indicators, which are heterogeneous, and it is practically impossible to reduce them to a common denominator.
Mistake in the diagnosis of hemorrhagic fever with renal syndrome
Authors: Hunafina D. H. , Volegova G. M. , Mamon A. P. , Abdrakhmanov M. M. , Mamon S. I.
Published: March 2022

We observed 300 patients with GLPS, in 150 of whom the disease was accompanied by abdominal pain. The usual corrective conservative therapy resulted in abdominal pain abatement, cessation of vomiting and recovery. Some patients had severe pains and had to be relieved by injections of 50% analgin solution with dimedrol and 1% promedol solution. They were especially intensive on days 3-6 of the disease during hemorrhagic and renal manifestations.
Ventilation-perfusion relationships in smokers
Authors: Andreev V. M. , Zhungin P. D.
Published: March 2022

To assess the effect of smoking on ventilation-perfusion relations in 62 smokers and 30 non-smokers aged 20 to 57 years old we used mass spectrometry to determine partial pressure of O2 and CO2 in alveolar air (pАО2 and рАСО2) and growth rate of рСО2 in alveolar exhalation phase (pACO2/tA).To exclude heart and lung diseases, in addition to the general clinical examination, we studied GEL, SPR1 and Wotchal-Tiffno index. These indices in the healthy and smoking groups were within normal limits and did not differ significantly, although they were slightly decreased in smokers.
Morbidity of university and pedagogical institute students in Yoshkar-Ola
Authors: Kamaeva A. A. , Khaletova S. S. , Bakshaeva M. A.
Published: March 2022

During 1974-1976 and 1983-1986 we studied the state of health of university students in Yoshkar-Ola. For each period the health characteristics of 4440 students were presented, separately by faculties and courses, and the structure of diseases was traced.According to our observations, during 1983-1986 there was some increase in general morbidity of students of both universities. According to the analysis of morbidity, students most often sought medical assistance for colds (acute respiratory infections-42.7%), ENT-organ diseases (pharyngitis, maxillary sinusitis, angina-11.2%), injuries (sprains, strains, bruises of the upper and lower extremities-12%), gastrointestinal diseases (gastroduodenitis, duodenal ulcer, cholecystitis, biliary and intestinal dyskinesia - 4.6%), less often - due to cardiovascular (hypertension, neuro-circulatory dystonia) and pulmonary (bronchitis, chronic pneumonia -3.6%) diseases. Dental diseases were represented by dental caries, typical for students of both universities.
The medical intelligentsia of Tatarstan (touches to a social portrait)
Authors: Khaziakhmetova V. S.
Published: March 2022

The social structure of Soviet society is one of the most urgent problems from the sphere of social sciences. Intellectuals attract considerable attention: the features of their social appearance, the nature of their professional detachments, the peculiarities of their replenishment, etc. The development of the Soviet medical intelligentsia at the present stage remains one of the least studied problems. Doctors, pharmacists, paramedics, nurses, laboratory staff, sanitary services, physical education instructors, i.e., about 1200 thousand doctors of almost 200 specialties, 3159 thousand middle medical personnel, etc., should be referred to this social-professional group acting as a sub-element of the social structure.
Conductor for tendons
Authors: Nettov G. G.
Published: March 2022

Conducting the injured end of the tendon under the finger block ligament in the so-called critical zone presents significant technical difficulties. Narrowness of the lumen under the block ligament leads to usbarization, unravelling of the conducted tendon end, and repeated attempts lead to traumatization of both the block ligament and the tendon end, and to an increase in the operation time. The use of the existing guide from V.I. Rozov's set does not eliminate the above drawbacks. If it is impossible to guide the tendon, it is often necessary to longitudinally dissect the block ligament with its subsequent suturing over the tendon, which leads to scar adhesion of the tendon with the sutured ligament in the postoperative period. This prolongs the immobilization period and worsens the functional outcomes of the surgery.
Device for skin perforation and preparation of thin dermal strips
Authors: Izmailov G. A. , Toporkov N. P. , Chenborisov V. Sh. , Gabdrakhmanov F. G. , Izmailov S. G. , Garaev R. R.
Published: March 2022

To obtain a perforated skin flap and dermal strips, we proposed a device that has rollers and a cutting plate with cutters.
Professor Nikolai Sergeevich Strelkov: the 70th anniversary of birth
Authors: Shubina Z. V.
Published: March 2022

The article is dedicated to the 70th anniversary of the birth of Strelkov Nikolay Sergeevich - Russian scientist, Honored Doctor of the Russian Federation, Doctor of Medical Sciences, professor, pediatric surgeon, State Prize Laureate of the Udmurt Republic.
Integral leukocgram indices in children with coronavirus infection COVID-19
Authors: Korotaeva K. S. , Furman E. G. , Sumlivaya Olga N.
Published: March 2022

Objective. To study the changes in hematological leukocyte indices among children with coronavirus infection COVID-19 in the dynamics of infectious process.

Materials and methods. The work is based on the analysis of clinical and laboratory data from 91 pediatric patients with COVID-19. On the basis of a general blood test, the following hematological leukocyte indices were determined: the entropy degree of leukogram according to A.V. Gorelov et al.; leukocyte intoxication index according to V.K. Ostrovsky; nuclear endotoxicosis degree index according to G.D. Dashtayants; Harkavi adaptation index; Krebs index; leukocyte index; neutrophils to monocytes ratio index; lymphocytes to monocytes ratio index.

Results. The most sensitive hematological indices were the entropy degree of leukogram according to A.V. Gorelov et al., indicating a violation of the dynamic constancy of leukogram; neutrophils to monocytes ratio indices, lymphocytes to monocytes ratio indices, showing the presence of a viral infection. At the peak of the infectious process, C-reactive blood protein index significantly correlated with the endotoxicosis index according to G.D. Dashtayants (R = 0.271; p0.05), with neutrophils to monocytes ratio index (R = 0.276; p0.05); and in the period of early convalescence - with leukocyte intoxication index according to V.K. Ostrovsky (R = 0.743; p0.05), with endotoxicosis indices according to Dashtayants (R = 0.785; p0.05) and neutrophils to monocytes ratio index (R = 0.743; p0.05).

Conclusions. The calculation of hematological leukocyte indices increases the information capability of the general blood test in children with coronavirus infection COVID-19, provides important additional information on intoxication syndrome, the state of immune response, the persistence of inflammatory process during the period of convalescence as well.
Modification of emulsified fat (nanofat) obtaining procedures
Authors: Khramtsova N. I. , Plaksin S. A. , Gulyaeva N. I. , Sotskov A. Yu. , Ponomarev D. N.
Published: March 2022

Objective. To modify the procedure by reducing the number of filters and passages through them.

Materials and Methods. 16 samples of fat, aspirated by a syringe from the abdominal region were examined. Fat filtration was carried out through anaerobic fat transfers with an inner diameter of 1.4 mm and 1.2 mm, as well as an emulsifying filter (nanofat filter). The content of destroyed adipocytes and fibroblast-like cells was assessed.

Results. The 1.2 mm filter with 10 passages protocol provides determination of the minimal number of adipocytes while maintaining fibroblast-like cells. While filtrating through the 1.4 mm transfer, and then immediately through the nanofat filter, numerous connective tissue fibers with fibroblast-like cells are identified. When filtrating an adipose tissue using the 1.4 mm transfer 10 times, then using nanofat filter 5 times, there was obtained a homogeneous fat emulsion with a high content of morphologically intact adipocytes, the particle diameter of which allows injecting with a thin needle syringe.

Conclusions. To obtain nanofat, it is possible to optimize the lipograft filtration protocol proposed by P. Tonnard (2013), depending on the purpose of using the obtained product.