bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the Role of Art in Career Transition and Development
Authors:   Faculty of Business, Kampala International University, Uganda, Nabirye H. Kato
Published: December 2024

This paper examines the intersection of art and career transition, uncovering how artistic practices foster self-discovery, emotional resilience, and meaningful career development. It identifies four key objectives: understanding individuals’ insights into the role of art during career transitions, exploring narrative-based approaches to career practice through art, linking findings with art therapy literature, and critiquing career practitioners’ approaches to artistic integration. Grounded in the dual theoretical frameworks of ‘art as object’ and ‘art as experience,’ this work emphasizes the transformative power of art in enhancing personal narratives and self-reflection. By synthesizing evidence from art-based interventions and real-world case studies, the paper demonstrates the role of visual arts, improvisation, and other creative mediums in reducing anxiety, improving decision-making, and fostering adaptability. The findings underscore the need for holistic, art-infused career counseling practices, proposing practical recommendations for incorporating artistic approaches into career development pathways.

Keywords: Art-based interventions, career transition, career development, art therapy, creative approaches.
Ep 05 - Rewriting the Rules: A Dynamic Approach to Gene Synthesis Security
Authors: Titus Alexander
Published: December 2024

Hey there! I'm excited to dive into a recent white paper from the NSCEB on strengthening gene synthesis security. As someone who's deeply passionate about the intersection of AI and life sciences, this topic is fascinating because it seems simple, yet it is oh so hard. Let's break it down and explore what it means for our field and society at large.

Before I do, I have to laugh at how challenging it is for the AI podcast hosts to say NSCEB.
Ep 00 - Podcast About the NSCEB's Interim Report
Authors: Titus Alexander
Published: December 2024

The National Security Commission on Emerging Biotechnology (NSCEB) has produced an interim report that focuses on the potential of biotechnology to transform society and improve national security.
Ep 06 - Biodefense 2.0: BWC in the Modern Age
Authors: Titus Alexander
Published: December 2024

Hey there, science and policy enthusiasts! It's Titus here, and I'm thrilled to bring you this special edition newsletter on a topic that's close to my heart: the Biological Weapons Convention (BWC). Remember last week’s issue, when I promised more on the BWC soon?
Ep 02 - Data, data, data. What's with all the data?
Authors: Titus Alexander
Published: December 2024

Hey, my friends! Today, we're venturing into a realm that's as vast and complex as life itself: the world of biological data and its implications for U.S. biotechnology leadership. This is based on the white paper from the National Security Commission on Emerging Biotechnology (NSCEB) titled "Leveraging Biological Data." Like last week, the podcast audio is AI-generated, and they keep calling this a report.
Ep 14 - The Agricultural Revolution 2.0: How Biotechnology is Rewriting the Rules of Farming
Authors: Titus Alexander
Published: December 2024

The Ancient Roots of Agricultural Innovation

Agriculture is undergoing a revolution, one shaped by the transformative power of biotechnology. This field, at the intersection of science, policy, and industry, promises to address some of the most pressing challenges of our time.
Exclusionary rule and evidentiary prohibition in American law
Authors: Stanković Bojana
Published: December 2024

The rules on the exclusion of evidence are one of the few rules, which, due to their characteristics, cannot be polarized into the Anglo-Saxon model and the European-continental model. A unique model of exclusion of evidence exists in American law, which is the creator of the exclusionary rule, while in other countries of the Anglo-Saxon system and the European-continental system, a relative system of exclusion is represented in its autonomous forms. Under the influence of numerous Anglo-American doctrines and judicial practice of courts in the USA, a system of absolute separation was established, which is based on the protection of the constitutional rights of citizens, with the fact that this approach was relativized over time through exceptions that were accepted in practice. In this paper, the author deals with the origin and characteristics of the exclusionary rule, the differences in relation to the relative system of extracting evidence and the most important evidentiary prohibitions, which arose as a con sequence of the violation of the constitutional amendments. The emergence of evidentiary prohibitions in the USA, especially those related to the prohibition of self-incrimination and the prohibition of Hearsay, is of great importance for these generally accepted institutes of Anglo-Saxon law, but also for the standards of the ECtHR, as shown by the practice of the highest judicial instance of the USA, which was analyzed in the paper.
Membership interests in a limited liability company
Authors: Nikolić Dušan
Published: December 2024

The author analyzes the notion of membership interests in a limited liability company under Serbian law. Membership interests in a limited liability company represent one of the most significant notions characterizing the entire form of a limited liability company. Considering the scope of the membership interests' notion, the analysis is divided into three sections at the beginning of the analysis. The first section addresses basic terminological and conceptual considerations. The second deals with issues of the legal nature of membership interests, while the third includes an analysis of principles related to membership interests. Regarding the legal nature of membership interests, special emphasis is placed on examining the nature of membership interests in comparison with the related notion of shares in joint-stock companies and the legal notion of digital assets. Finally, the nature of membership interests is also analyzed from the perspective of property law. In the final section, the principles of proportionality and will autonomy that shape the concept of membership interests are presented, followed by an analysis of their application in current positive law. The conclusions from the analysis of certain open questions within the notion of membership interests should serve as a basis for future improvements of this legal notion, particularly in the part relating to the application of the will autonomy principle.
Legal status of religious communities in socialist Yugoslavia
Authors: Đukić Dalibor
Published: December 2024

After the Second World War, Yugoslavia, like other Communist regimes, implemented the separation of church and state, coupled with an aggressive secularization that permeated all aspects of society. However, the Yugoslav model of state-religion relations diverged from the typical Communist approaches in Eastern Europe. This paper analyzes this unique model by examining the in fluence of three key factors. The first factor is time. The Yugoslav state's approach to religion evolved over time, shifting from widespread persecution of believers and religious officials to a more cooperative stance, eventually leading to agreements that regulated the rights of specific religious organizations. This paper tests the thesis that, over time, the Yugoslav model gradually moved away from abolitionist system of complete religious freedom restriction towards a model of secular control over religious organizations with a strict separation of church and state. The second factor is territory. In the field of ecclesiastical law, it is widely recognized that identifying the model of state-religion relations within a single state can be a complex task, particularly in federations where the regulation of religious freedom is often devolved to federal units. This paper examines the extent to which the implementation of the Yugoslav model varied across different federal units, how these practices were reflected in legal norms, and what the causes and consequences of these differences were. Finally, the third factor is the subjects of religious freedom. While the principle of equal treatment for all religious organizations should theoretically apply in models of church-state separation, this was not always the case in Yugoslavia. The state's treatment of religious organizations was not uniform, and this paper explores how these dis parities were regulated and the underlying reasons for such practices.
O corpo criador de narrativas teatrais: influências do trabalho corporal na escrita de uma dramaturgia amazônida
Authors: Martins Benedita Afonso , Gibson Bárbara Toscano
Published: December 2024

Este artigo tem a finalidade de tecer entendimentos sobre corpo-dramaturgia num contexto teatral a partir de situações experenciadas na carreira de uma atriz-dramaturga-diretora-pesquisadora que escreve e dirige espetáculos em Belém do Pará desde 2011. A premissa é que o trabalho corporal de artistas pode influenciar diretamente no desenvolvimento dramatúrgico, uma vez que o corpo em si é constante criador de sensações, gestos, percepções, narrativas. Buscando expandir a discussão, referenciais teóricos e exemplos concretos são utilizados para examinar conceitos relevantes como textocentrismo, dramaturgia expandida e corporeidades, que auxiliam numa compreensão mais ampla de dramaturgia corporal.
Research Report “The potential of focus groups as a strategy for participatory technology development for promoting mental health”
Authors: Girardi Katyane Heck , Zanatta Leila , Zocche Denise Antunes de Azambuja
Published: December 2024

Due to the high demands in the mental health field, this study aimed to present the use of FG as a tool for the participatory technology development for promoting mental health in Primary Health Care (PHC). This action research was performed in a city in the Midwest of Santa Catarina, Brazil. Data were collected through a focus group that met once. Two professors from the Professional Master’s Program in PHC Nursing and 15 PHC workers from the mental health field participated in the focus group. The information was collected in October 2022, and the data treatment was guided by content analysis. The health workers’ experiences in mental health include a concern with adolescents and women, as they identify the need to implement care practices to strengthen protective and preventive mental health factors. Educational gymkhanas, online psychoeducational interventions, and a podcast emerged as care strategies to be implemented in mental health within PHC. The perceptions of the PHC workers regarding mental health needs and demands enabled defining the public audience and the educational technology that needs to be developed to promote and protect the mental health of PHC service users.
Efeito de dois métodos de poda no desempenho agronômico da videira ‘Chardonnay’ cultivada em região de altitude de Santa Catarina
Authors: Würz Douglas André , Souza Deivid Silva de , Rufato Leo
Published: December 2024

O objetivo deste trabalho foi avaliar o efeito de dois métodos de poda no desempenho agronômico da videira ‘Chardonnay’ cultivada em região de altitude de Santa Catarina. O presente trabalho foi realizado durante a safra 2018/2019, em um vinhedo comercial localizado no município de São Joaquim. Na poda curta foram deixados esporões com duas gemas, e na poda longa, duas varas com oito gemas cada e um esporão contendo duas gemas para renovação no ano seguinte. Avaliou-se: produção (kg/planta), número de cachos (cachos/planta), produtividade (t ha-1), comprimento de cachos (cm), massa de cachos (g), número de bagas, sólidos solúveis (°Brix), acidez total titulável (meq L-1) e pH. O método de poda influenciou diretamente o desempenho agronômico da videira ‘Chardonnay’, no entanto, apesar da poda curta resultar em maior número de cachos/planta, esse método de poda apresentou cachos com menor número de bagas e menor massa de cachos, resultando em produção e produtividade semelhantes entre os dois métodos de poda. Além disso, a diferença de maturação tecnológica pode estar diretamente relacionada a arquitetura de cachos, visto que índices produtivos foram semelhantes entre os tratamentos, no entanto, a poda longa apresentou menor acúmulo de sólidos solúveis, e apresentou maior número de bagas/cacho, e maior massa de cachos.
Movimentos de design no novo paradigma antropocêntrico
Authors: Ambrosio Vanessa Constance , Sousa Richard Perassi Luiz de , Dias Junior Claudelino Martins
Published: December 2024

Este artigo busca trazer à tona uma reflexão sobre o Paradigma Antropocêntrico do Design Moderno e a responsabilidade dos designers e profissionais afins enquanto agentes na reprodução de pensamentos e comportamentos decorrentes do progresso moderno, na criação e produção de objetos e serviços atualmente. Do mesmo modo, sugere como o Design pode corroborar nas transformações futuras, considerando aspectos socioeconômicos, políticos e culturais em acordo com as alterações climáticas ao longo das últimas décadas. Discorre, por meio de uma revisão bibliográfica e sem extenuar o tema, perspectivas em se lidar com novas representações, narrativas e práticas que acarretem num modo de viver pleno e diferente das previsões catastróficas e alarmantes para um futuro próximo, considerando a interferência humana em todas as formas vivas da Terra. Em síntese, tem-se uma reflexão e a indicação de movimentos de contribuição possíveis no Campo de Design, dado como resultado de uma pesquisa com abordagem qualitativa e do tipo descritiva sobre representações, narrativas, práticas e projetos de Design integrados e direcionados ao bem-estar das pessoas e associado à responsabilidade socioambiental.
دور الذكاء الاصطناعي في تحسين الأداء المالي باستخدام بطاقة الأداء المتوازن للبنوك التجاريّة الأردنيّة (دراسة تحليلية من وجهة نظر العاملين بالبنوك)
Authors: الطراونة حسين
Published: December 2024

هدفت هذه الدراسة إلى تبيان دور الذكاء الاصطناعي في تحسين الأداء المالي باستخدام بطاقة الأداء المتوازن للبنوك التجاريّة الأردنيّة سيما وأن استخداماته شملت كافة مناحي الحياة ومنها القطاع المصرفي، حيث اتبعت هذه الدراسة المنهج الوصفي التحليلي واختيار عينة عشوائية وباستخدام أداة جمع المعلومات وهي الاستبانة وبعد تحديد عدد مجتمع الدراسة الذي بلغ (66) تم توزيع الاستبيانات على العينة التي بلغ عددها (56) حيث تم استرجاع (52) وكانت جميعها صالحة للتحليل وبلغت نسبتها 92.85% من حجم العينة الموزعة لمجموعة من موظفي البنوك التجاريّة الأردنيّة، وقد توصلت الدراسة إلى مجموعة من النتائج منها أن غالبية البنوك التجاريّة الأردنيّة تتجه نحو استخدام تطبيقات الذكاء الاصطناعي بشكل يواكب التطور التكنولوجي وكذلك أظهرت النتائج بوجود دور إيجابي وذو دلالة إحصائية لاستخدام الذكاء الاصطناعي في تحسين الأداء المالي باستخدام بطاقة الأداء المتوازن، وكذلك وجود أثر إيجابي بين الذكاء الاصطناعي ممثلاً بأبعاده وبين بطاقة الأداء المتوازن، ولكن هذا الأثر ضعيف جداً، وهذا واضح من القيمة الاحتمالية التي تراوحت في الأبعاد، رؤية الحاسوب 28.1%، التعلم 59.1%، التنبؤ 3.1%، ومعالجة اللغة الطبيعية 57.4% وباختلاف نسبي بين تلك الأبعاد، أما أبرز التوصيات لهذه الدراسة فكانت بأنه يتوجب على البنوك التجاريّة الأردنيّة ضرورة العمل الدؤوب في تطوير منظومة العمل المصرفي من خلال التوسع باستخدام تطبيقات الذكاء الاصطناعي، وكذلك يتوجب على البنوك عموماً والبنوك التجاريّة بشكل خاص ضرورة إيلاء موضوع التدريب للعاملين على أحدث التقنيات والتطبيقات التي تخص الذكاء الاصطناعي وأخيراً أوصت الدراسة بإجراء المزيد من الدراسات وربط الذكاء الاصطناعي مع متغيرات أخرى لم تتم دراستها مثل دور الذكاء الاصطناعي في الحد من حالات التعثر في سداد القروض للبنوك التجاريّة على سبيل المثال واستخدام أبعاد أخرى للذكاء الاصطناعي.
أثر استخدام إستراتيجية تدريسية قائمة على الذكاءات المتعددة في اكتساب المفاهيم الرياضية والقدرة على حل المسائلة الرياضية والدافعية نحو تعلم الرياضيات لدى طلبة الصف التاسع الأساسي
Authors: الحراحشة وسام , نجم خميس
Published: December 2024

هدفت الدراسة إلى معرفة أثر استخدام إستراتيجية تدريسية قائمة على الذكاءات المتعددة في اكتساب المفاهيم الرياضية والقدرة على حل المسائلة الرياضية والدافعية نحو تعلم الرياضيات لدى طلبة الصف التاسع الأساسي، وقد تم الاعتماد على المنهج التجريبي ذو التصميم شبه التجريبي، ولتحقيق أهداف الدراسة تم اختيار عينة مكونة من (42) طالبًا من طلبة الصف التاسع الأساسي، منهم (22) مجموعة تجريبية، و(20) مجموعة ضابطة، تم اختيارهم بالطريقة القصدية، وذلك في العام الدراسي 2023/2024م، وتم إعداد وحدة الهندسة وفقًا لإستراتيجية الذكاءات المتعددة، وتم استخدام اختبار اكتساب المفاهيم الرياضية مكون من (15) سؤالًا من اختيار متعدد، واختبار حل المسائلة الرياضية مكون من (10) أسئلة مقالية، ومقياس الدافعية للتعلم مكون من (27) فقرة، وأظهرت نتائج الدراسة تفوق طلبة المجموعة التجريبية في اختبار اكتساب المفاهيم الرياضية، واختبار حل المسائلة الرياضية، ومقياس الدافعية نحو نعلم الرياضيات، مما يدل على فاعلية استخدام استرتيجيات التدريس القائمة على الذكاءات المتعددة في اكتساب المفاهيم الرياضية والقدرة على حل المسائلة الرياضية والدافعية نحو تعلم الرياضيات لدى طلبة الصف التاسع الأساسي.
Çanakkale Ayvacık'a Bağlı Yukarıköy ve Çamkalabak Köylerinde Doğum Gelenekleri
Authors: Çakır Berkcan
Published: December 2024

Geçiş dönemlerinin ilki olan doğum, insan hayatının ilk eşiği olarak kabul edilir. Üreme ve soyu sürdürmenin başlangıcı olan doğum, yalnızca anne ve baba için değil, aile ve toplum için de sevindirici bir olaydır. Bu nedenle, her toplum, çocuğun dünyaya gelmesi, sağlıklı bir şekilde büyümesi ve kültürel değerleri yansıtan çeşitli ritüel ve uygulamaları temel alarak farklı inanışlar ve gelenekler geliştirmiştir. Ancak günümüzde hızla gerçekleşen küreselleşme sonucunda, birçok geleneğin ülkemizde unutulmaya yüz tuttuğu gözlemlenmektedir. Bu nedenle, geçiş dönemi ritüel ve uygulamalarının kayıt altına alınması ve yazılı hale getirilmesi büyük bir önem taşımaktadır. İnceleme alanımız olan Yukarıköy ve Çamkalabak köylerinde yaşayan Yörüklerin, geleneksel yaşam tarzlarını ve kültürel miraslarını sürdürdükleri dikkate alındığında, doğum ile ilgili ritüel ve uygulamaların günümüzde hâlâ canlı bir şekilde devam ettiği tespit edilmiştir. Bu ritüellerin ve uygulamaların, Yörük topluluklarının hayatlarının vazgeçilmez bir parçası olduğu sonucuna ulaşılmıştır. Ayrıca, tespit edilen doğumla ilgili ritüel ve uygulamalar, Türk Dünyası'ndaki geçiş dönemi ritüel ve uygulamaları ile karşılaştırılmış; yapılan incelemeler sonucunda bu benzerlikler ve farklılıklar açıklanarak ortaya konmuştur.
Relationship between Fibrinogen Values and Sensitivity and Specificity of STS Score, Euroscore for Patients Undergoing Open Heart Surgery
Authors: Aydınlı Bahar , Tekin Esra Ertürk , Yeşiltaş Mehmet Ali , Oksen Doğaç , Özmen Harun
Published: December 2024

Background/Aim: Cardiovascular diseases are a leading cause of mortality worldwide, with surgical interventions playing a crucial role in outcomes. Despite technological advancements and improved operator experience, perioperative and postoperative risks remain significant, particularly for high-risk patients. Fibrinogen, an acute-phase reactant, increases during inflammation and plays a role in coagulation. This study investigates the prognostic impact of fibrinogen levels on the outcomes of cardiac surgery and evaluates its relationship with established risk classification systems. Materials and Methods: This observational cohort study included 105 patients who underwent cardiac surgery between May 2018 and December 2023. Patients with coronary bypass grafting and valve surgery were included, while those with transplantation, congenital heart surgery, or other significant conditions were excluded. Patient data, including demographic information, comorbidities, laboratory parameters, and surgical details, were collected. The fibrinogen cutoff value was determined using the Youden index. Statistical analyses were performed using SPSS 23.0, with p-values < 0.05 considered significant. Results: Of the 116 individuals screened, 105 were included in the study. The HighFib group (>3.8 g/dL) showed higher rates of complications, such as low cardiac output, prolonged mechanical ventilation, and atrial fibrillation, compared to the LowFib group (<3.8 g/dL). The HighFib group also had lower preoperative hemoglobin levels and higher Euroscore values. Logistic regression analysis demonstrated that both fibrinogen levels and established risk scores were significant predictors of postoperative complications. Conclusion: Elevated fibrinogen levels are associated with increased postoperative complications in cardiac surgery patients. Fibrinogen, alongside traditional risk scores, can be a valuable predictor of adverse outcomes. Prospective studies are needed to further validate these findings and establish optimal fibrinogen management strategies in cardiac surgery.
Pelatihan Pengelolaan Manajemen Keuangan Santri yang Efektif dan Efisien bagi Pondok Pesantren Tahfidz Qur’an Bani Salam Cipondoh Tangerang
Authors: Naufalia Viani , Windasari Vicky , Shadiq Helmy Moehammad , Gurhanawan
Published: December 2024

Keuangan atau finansial merupakan salah satu sumber daya yang secara langsung menunjang efektifitas dan efisiensi pengelolaan pendidikan pondok pesantren. Dengan adanya manajemen/pengelolaan keuangan yang baik dana yang diperlukan untuk kegiatan pesantren dapat digunakan untuk merencanakan, mencari pendanaan, mencatat secara sistematis dan transparan, serta mendanai pelaksanaan program pesantren secara efektif dan efisien. Salah satu karakteristik pesantren yang maju adalah adanya tatakelola keuangan yang baik yang mendorong tersedianya informasi keuangan yang relevan dan andal bagi pengelola pesantren maupun pihak yang berkepentingan lainnya. Informasi keuangan tersebut berguna sebagai salah satu landasan dalam pengambilan keputusan ekonomi pengelolaan pesantren.
Position on The Arrangement of Administrative Sanctions By The KPPU Institution In State Science
Authors: Alsyam
Published: December 2024

The position of the Business Competition Supervision Commission as a business competition court in imposing administrative sanctions (administration Punisment) to the guilty perpetrator. Looking at the constitutional system in a state institution in Indonesia, it has its own proportional functions in law enforcement. According to Article 36 letter i of Law Number 5 of 1999 concerning Prohibition of Monopoly Practices and Unfair Business Competition that "Imposing sanctions in the form of administrative action on business actors who violate the provisions of this Law”. However, according to the provisions of this rule in Article 44 paragraph (2) that "Business actors can submit objections to the District Court no later than 14 (fourteen) days after receiving notification of the decision”. Types of research in legal writing will be carried out using normative legal methods (doctrinal research) or called Studi dogmatic. The research approach uses the Law approach (statue approach), case approach (cases approach), and analytical approaches (analitycal approach).  The research results explain that First, Constitutionally, the KPPU institution, given the task of adjudicating a report, assists the role of the judiciary in enforcing unfair business competition law. This is of course that in state administration there are still different roles in each institutional structure in Indonesia. Second, basically the role of the KPPU institution where the imposition of sanctions is administrative in the sense of carrying out supervision of the Antimonopoly Law based on the specific duties of the Law. Third, The KPPU's position as an independent institution in enforcing business competition law is Punitive  which is given to business actors based on the results of the inspection. The KPPU provides administrative sanctions as a preventive measure against the reported parties who engage in unfair business competition.
ON EFFECTS OF INITIAL CF4 + CHF3 + O2 MIXTURE COMPOSITION ON PLASMA PARAMETERS AND REACTIVE-ION ETCHING OF SILICON
Authors: Efremov Alexander M. , Bobylev Alexander V. , Kaznacheeva Ekaterina M. , Kwon Kwang-Ho
Published: December 2024

In this work, we discussed how the CF4/CHF3 ratio in CF4 + CHF3 + O2 gas mixture does influence steady-state plasma composition and silicon etching kinetics in a conventional reactive-ion process. Plasma diagnostics by double Langmuir probes delivered the information on electro-physical plasma parameters and provided input data for the modeling of plasma chemistry. As a result, we confirmed basic properties of CF4 + O2 and CHF3 + O2 plasmas known from previous works as well as analyzed formation/decay kinetics for plasma active species in the three-component gas mixture. In particular, it was found that the substitution of CF4 by CHF3 at fixed content of oxygen in a feed gas a) causes weak changes in electron temperature and plasma density; b) leads to an increase in plasma polymerizing ability; and c) sufficiently (by more than 3 times) reduces F atom density. The last effect was confirmed by the satisfactory agreement with experimental data obtained using the optical emission actinometry method. Etching experiments indicated a monotonic decrease in Si etching rate toward CHF3-rich plasmas, from 140 nm/min down to 65 nm/min. The analysis of etching kinetics allowed one to conclude that a) the dominant etching mechanisms is the ion-assisted chemical reaction; and b) the effective reaction probability keeps the nearly constant value, in spite of increasing polymer deposition rate. This effect may reflect the change in passivation of polymer-free surface by oxygen atoms.
For citation:
Efremov A.M., Bobylev A.V., Kaznacheeva E.M., Kwon K.-H. On effects of initial CF4 + CHF3 + O2 mixture composition on plasma parameters and reactive-ion etching of silicon. ChemChemTech [Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol.]. 2025. V. 68. N 1. P. 39-47. DOI: 10.6060/ivkkt.20256801.7096.
SYNTHESIS AND BIOLOGICAL ACTIVITY OF AMMONIUM SALTS CONTAINING CYCLOACETAL FRAGMENT
Authors: Borisova Yulianna G. , Sultanova Rimma M. , Zlotsky Simon S.
Published: December 2024

Interaction of consecutive chain amines (pyridine, 2-methyl-pyridine, 4-vinyl-pyridine, 4-(1,3-dioxolan-2-yl)pyridine) with bromo derivatives (allyl bromide, benzyl and 2-β-bromoethyl-1 ) ,3-dioxolane), new quaternary ammonium salts were synthesized under thermal conditions containing allylic (1-allylpyridinium-, 1-allyl-4-vinylpyridinium- and 1-allyl-4-(1,3-dioxolan-2-yl) pyridinium bromides), benzyl (1-benzyl-4-vinylpyridinium-, 1-benzyl-4-(1,3-dioxolan-2-yl)pyridinium bromides) or 1,3-dioxolanoate (1-[2-(1 ,3-) dioxolan-2-yl)ethyl]pyridinium-, 1-[2-(1,3-dioxan-2-yl)ethyl]-2-methylpyridinium-, 4-(1,3-dioxan-2yl) -1-[2-(1,3-dioxolan-2-yl)ethyl]pyridinium bromides) fragments. It was found that, in contrast to acetonitrile, when using methyl ethyl ketone as a solvent, the synthesis time is reduced by 2 times, while the yield and selectivity remain the same (≥ 95%). The best yield was achieved using allyl bromide (1-allylpyridinium bromide) in the alkylation of heterocyclic bases (pyridine, 2-methyl-pyridine, 4-vinyl-pyridine, 4-(1,3-dioxolan-2-yl)pyridine). The yield of 2-β-bromoethyl-1,3-dioxolane of the corresponding QAC decreased to 70% (1-[2-(1,3-dioxolan-2-yl)ethyl]-2-methylpyridinium bromide). The structures of compounds obtained have been studied in detail using NMR spectroscopy methods. The cytotoxic activity of salts was determined using the MTT method in vitro when applied to conditionally normal cell lines Hek293 (human embryonic kidney cell lines) and to tumor lines using HTC-116 (human colorectal carcinoma), MCF-7 (human breast adenocarcinoma), HepG2 (human hepatocellular carcinoma). It has been established that the resulting substance is not applicable when applied to conditionally normal and tumor cell lines, except for 1-benzyl-4-vinylpyridinium bromide culture, which exhibits moderate cytotoxic activity against these cell cells. Thus, for HEK293 cells, the IC50 concentration was 75.48 ± 9.26 μM, IC50 = 46.16 ± 5.76 for MCF-7 cells, IC50 = 61.85 ± 3.41 for HepG2 cells, IC50 = 58.88 ± 2.59 for HCT-116 cells.
For citation:
Borisova Yu.G., Sultanova R.M., Zlotsky S.S. Synthesis and biological activity of ammonium salts containing cycloacetal fragment. ChemChemTech [Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol.]. 2025. V. 68. N 2. P. 46-51. DOI: 10.6060/ivkkt.20256802.7002.
Impacto de la terapia hipolipemiante sobre la variabilidad de la HbA1c en pacientes con prediabetes de la consulta de medicina interna y la Unidad de Diabetes del Hospital Vargas De Caracas
Authors: Marchan Analiesse , García Martínez Edgar José , Escalona Lucymar , Strocchia Puigbó Raúl , Ramirez Rodriguez Ligia Maria , Réquiz Zully Andreína , Carrera-Viñoles Fernando Javier
Published: December 2024

Introducción: La terapia hipolipemiante tiene un impacto en los parámetros glucométricos y lipídicos. Esto puede resultar en una mejora de la sensibilidad a la insulina y una reducción en los niveles de glucosa en sangre. Existe una asociación entre el uso de estatinas y el riesgo de desarrollar diabetes, por lo que es importante evaluar el riesgo cardiovascular en pacientes con prediabetes que usen esta terapia. Objetivo: Determinar la variabilidad de los parámetros glucométricos en pacientes con prediabetes en tratamiento hipolipemiante. Métodos: investigación clínica de tipo observacional analítico bajo un diseño de cohorte tipo 2, retrospectivo y corte longitudinal. Incluyó 316 pacientes del área de consulta externa del servicio de medicina interna- Hospital Vargas de Caracas, período enero 2022- noviembre 2023. Resultados: edad promedio de 69,1 años, el 65,51% correspondieron al sexo femenino. El 57,6% recibió terapia combinada. Con las estatinas de alta intensidad tuvo un aumento porcentual del 1,2% en promedio (p=0,009) de HbA1C, mientras que ácido bempedoico, se observó una disminución de 0,2% en promedio (p=0,001). El ezetimibe no generó variabilidad en la modificación final. El ácido bempedoico logró reducir de manera significativa los niveles de HbA1c. El uso de estatinas de alta intensidad aumentó la HbA1C, lo cual demuestra resultados similares con otras investigaciones. La terapia que más disminuyó los valores de LDL-C fue Ezetimibe con estatinas de alta intensidad. Conclusión: El uso del ácido bempedoico es prometedor para pacientes que presentan síndrome metabólico, ya que podría disminuir el riesgo de desarrollar diabetes en esta población.
Gondolatok a magyar labdarúgás könyvtárában: Értékelés 11 év múltán
Authors: Becsey Zsolt László
Published: December 2024

A szerző egy évtizeddel korábban megírt tanulmánya alapján (Becsey 2013) a hangsúlyos magyar állami szerepvállalás kezdete (2011-13) óta elért eredményeket veszi számba és azokat a régiónkban a hasonló országokéval hasonlítja össze. Szintén aktualitást ad az elemzésnek az, hogy 2023 végén, maga a Magyar Labdarúgó Szövetség is készített egy statisztikai felmérést, melyben azt mutatta ki, hogy stabilizálódott a magyar élklubok helyzete az előző időszakhoz képest, sőt a válogatott és egy elitklub révén megjelentünk az európai kvalifikált csoportkörös küzdelmekben is, nőtt a labdarúgásban versenyszerűen résztvevők köre. Ugyanakkor a korábbi állami szerepvállalás időszakához képest nagyobb bevétel és személyi költségek, infrastrukturális fejlesztés ellenére a mélységi mutatókban (pl. utánpótlás eredmények, hazai játékpercek, átlagos nézőszám, játékjogok eladásának pénzügyi mérlege) nem tudtunk előrelépni a nagyobb piaci feltételeknek kitett hasonló környékbeli országokhoz képest. Konklúzióként javasolta az erősebb versenyjogi szemlélet (tulajdonosi-vezetői függetlenség, kisebb állami szubvenciós rendszer) megvalósítását.
A vallás a funkcionálisan differenciált társadalmakban
Authors: Török Balázs
Published: December 2024

A tanulmány célja annak feltárása, hogy a vallási rendszer milyen kölcsönhatásban áll más társadalmi rendszerekkel. A vizsgálódás során elkülönítjük a premodern és modern vallási formákat. A társadalmi rendszerek közötti strukturális kapcsolatokat a politikai és a tömegmédia működése alapján illusztráljuk. Bemutatjuk a vallási rendszer társadalmi mellőzöttségét, ami egyben a vallás más társadalmi rendszerektől való strukturális függetlenségeként is értelmezhető. Kiemeljük, hogy a politikai rendszer hogyan alakítja érzékenységét a vallási rendszer irányában. Emellett kitekintést adunk arra, hogy a vallás milyen módon befolyásolja a politikát azokban a társadalmakban, amelyekben a funkcionális differenciálódás még nem vált általános társadalomszervezési formává. A tanulmány vizsgálja, hogy a vallás jelenlegi társadalmi elszigeteltsége a nyugati társadalmakban milyen módon befolyásolja a társadalom vallási szempontú megfigyelhetőségét, értékelését, kritikáját. A tanulmányban a vallás szociológiai fogalmát alkalmazzuk, így minden olyan hitrendszert, amely transzcendens/immanens különbséget figyelembe veszi a valóság konstruálásában, a vallás egyik formájának tekintjük. A tanulmányban arra a kérdésre keressük a választ, hogy vajon a vallási rendszer milyen módon kap helyet a társadalmi rendszerek kölcsönhatásában? Milyen változásokat idézhet elő a vallási rendszerben, hogy a környezetében működő társadalmi alrendszerek kölcsönösen szorosabbra fűzik teljesítménykapcsolataikat, miközben a vallás irányában növelik érzéketlenségüket, vagy semleges viszonyt alakítanak ki irányában. Ilyen adottságok mellett hogyan pontosíthatja társadalmi funkcióját a vallási rendszer? (Megjegyezzük, hogy a szociológiai értelemben vett vallás nem azonos az egyháziasan rendszerezett vallásokkal. Társadalmi értelemben mindaz vallásinak tekinthető, ami transzcendens/immanens differencián alapuló valóságkonstrukciót kommunikál.)
Knowledge, Attitudes, and Practices of Medical Students Regarding use of Vitamin Supplements
Authors: Altaf Benash
Published: December 2024

Objective: To explore the knowledge, attitudes, and practices of medical students regarding use of
vitamin supplements, and compare them with the use of prescribed vitamin supplements.
Methodology: A cross sectional (KAP study) was conducted in public and private medical colleges of
Faisalabad, recruiting all the student enrolled in different specialities of medical sciences. Three
hundred and eighty-seven participants were recruited in this study over a period of two months
(Nov-Dec 2023) with help of convenient sampling technique. Subjects who filled incomplete form or
were not willing to participate in the study were excluded. A quantitative, close ended questionnaire was
floated on WhatsApp groups. Data was analysed using SPSS. P value≤0.05 was taken as significant.
Results: Study recruited 387 subjects of both genders, male 164 (42.4%) and female 223(57.6%) of
mean age 21.99±1.74 from different medical-related fields including MBBS 259 (66.9%), BDS
97(25.1%), Allied health Sciences 31 (8.0%) and freshly graduated students with the help of validated
questionnaire. It was filled by different medical colleges in Faisalabad. Forms were floated on Social
media and WhatsApp. It is shown that a significant number of the female population is using
vitamins as compared to males (P value=0.000). Moreover, a majority of the female population is
using it with a doctor's prescription as compared to males (P value=0.000)
Conclusion: Majority of the population are using the vitamin supplements after being prescribed by
the doctor though no biochemical analysis was done to assess the levels of essential vitamins.
Relationship of Histopathological Grades of Urothelial Carcinoma with Age and Gender
Authors: Omair Sidrah
Published: December 2024

Objectives: To assess the grades of urothelial carcinoma and their relationship with the demographic
determinants of age and gender.
Methodology: This descriptive cross-sectional study was conducted at the Department of Histopathology,
Combined Military Hospital, Lahore from May 2020 to January 2021. A total of eighty-five patients
irrespective of age and gender diagnosed by histopathology report as urothelial carcinoma along
with World Health Organization (WHO) Grading were included in the study. All the results were
subsequently analyzed using SPSS Version 23. Chi square test was applied to find the association
with p value≤0.05.
Results: Mean age of participants was 63.96±10.13 years ranging from 40 to 90 years. Most frequent
(41%) age group was 60-69 years and the least (7%) was 80-89 years. Of these 85 cases, 77 (90.59%) were
males and 8 (9.41%) were females. Regarding histological grade, 28 (32.9%) cases revealed low-grade
carcinoma and 57(67.1%) were high-grade urothelial carcinoma. Among high-grade cases, the most
frequent ones i.e. 22/57 lie in the age group 60-69 years while the least frequent cases i.e. 3/57 are in the
age group 40-49 years. Thus, the relation of age group with histopathological grades of urothelial
carcinoma was found to be significant (p-value 0.01) while it was not significant for gender (p-value 0.06).
Conclusion: The relation of the demographic factor, age with histopathological grades of urothelial
carcinoma was found to be significant while this relationship of grades was insignificant for gender.
Evaluating Optimal Practices in Compensatory Justice for Injured and Deceased Victims in the Workplace: Prospects for Bangladesh
Authors: Britya Binota Bose
Published: December 2024

The purpose of a compensatory mechanism is not to fully return the claimant to their previous State but rather through a monetary amount that, when combined with any residual earning capacity, will likely allow them to sustain themselves without relying on others for support. Compensation regarding workplace accidents is set by the Labour Act 2006. It would be accurate to say that this area of the Labour Act is not investigated and reviewed in the same way as the other areas because, despite years of enforcement and criticism for its apparent failure to uphold Justice, the amendment is not effective and sustainable in the long run and there is no realistic approach which may ensure compensatory Justice, where other countries show progressive realizations in the same field. This paper seeks to examine compensation systems in First World countries (UK, USA, India) to evaluate Bangladesh's mechanism. This study further evaluates the extent of the mechanisms that should be incorporated in Bangladesh and how the progressive approach can be implemented in labor law. This study was conducted using the qualitative method to analyze secondary data. The study finds out the failure of the Government in realizing practical scenarios for compensating workers. It also shows how the amendments lack significance in updating the mechanism progressively. However, this paper shows the government the criteria through which a labor law can adopt a progressive mechanism, competing with the other cited countries through inflation rate, standardization, and insurance schemes.

Keywords : Compensatory Justice, Employment Insurance, Industrial Accidents, Labour Policy, Workers.
Effect of Online Education Given to Young Adults on Testicular Cancer Health Beliefs and Behaviors
Authors: Yıldırım Mehmet Salih , Yıldız Esra
Published: December 2024

Objective: Early detection of testicular cancer is cost-effective and accessible through screening and promoting health beliefs tailored to awareness. Self-examination is equally vital, yet research on young adult males in Turkey regarding testicular cancer health beliefs and early diagnostic behaviors is limited. This study evaluates the effect of online educational interventions on shaping health beliefs in this population.
Methods: A randomized controlled experimental design was utilized, involving 112 males aged 18–35 attending family health centers under the Ağrı Provincial Health Directorate between April 2021 and June 2022. Using random sampling, 90 participants were selected. Data were collected via the "Introductory Information Form" and "Champion's Health Belief Model Scale." Statistical analyses included descriptive statistics, chi-square, Greenhouse-Geisser correction, Sphericity Assumption assessment, Cochran Q, McNemar test, and Independent Groups t-test.
Results: Sociodemographic characteristics were homogeneous between experimental and control groups (p > 0.05). The intervention, based on the Testicular Cancer Health Belief Model, significantly improved participants' health beliefs and behaviors. Positive changes were observed in perceived sensitivity, seriousness, benefits, and self-efficacy, alongside reduced perceived barriers (p < 0.05).
Conclusion: Online education positively influenced health beliefs related to testicular cancer, highlighting its potential in awareness and proactive health engagement. This study enriches the limited research on health beliefs and early diagnostics among young Turkish males, emphasizing the utility of digital platforms in addressing critical health concerns.
Prevention of sports injuries in college basketball players: An intervention study based on biomechanics
Authors: Zhang Yunbang , Tan Gongxia , Zou Hao
Published: December 2024

College basketball is becoming more and more popular, and as a result, more students are participating in the sport. This has led to a progressive rise in sports injuries, which has an impact on both academic performance and quality of life. Basketball players are mostly vulnerable to Anterior Cruciate Ligament (ACL) injuries due to certain movement patterns that raise their risk of damage. This study examines how biomechanical risk factors for ACL injuries in pre-adolescent basketball players are impacted by the JumpStart injury-prevention warm-up routine. The exercise that would lower the Peak Knee Valgus Moment (PKVM), a major risk factor for ACL injuries, was hypothesized. Further kinematic and biomechanical parameters were investigated. A total of sixty-two male and female basketball players were randomized and recruited into two divisions: the experimental group (EG) (n = 31) then the control group (CG) (n = 31). While the CG continued with their standard warm-up protocol, the experimental group took part in fifteen in-season JumpStart sessions. Motion capture data from pre- and post-season basketball-specific activities, such as jump landings, single-leg jumpers, and cutting movements, were gathered. SCONE simulator biomechanical modeling system was used to determine joint angles and moments in the lower extremities. Pre- and post-season data within groups were contrasted using paired t-tests, and the control and experimental groups were contrasted using independent t-tests. To assess the interaction effects among the EG and CG, an analysis of variance (ANOVA) was also achieved. The EG’s PKVM during jump landings was considerably lower (p < 0.01) than that of the CG, according to the results. These results show that the JumpStart program is beneficial in lowering the probability of ACL injuries in pre-adolescent basketball players and recommend future improvements to address other risk factors in single-leg and cutting activities.
The Influence of Financial Knowledge on Financial Planning Through Financial Strategy as a Mediating Variable A Study on School of Communication and Business Students, Telkom University
Authors: Mustafa Syah Jehan Afid , Kurnianingrum Dian , Fakhri Mahendra , Kartawinata Budi Rustandi , Dzakiy Uruqul Nadhif , Akbar Aldi
Published: December 2024

This study explores the significance of financial knowledge among students, specifically its impact on understanding financial behavior. It focuses on the relationship between Financial Knowledge and Financial Planning, with Financial Strategy acting as a mediating variable. Employing a quantitative descriptive research design, the research sample consists of 100 students from the Faculty of Communication and Business at Telkom University. Data analysis was conducted using path analysis and hypothesis testing through Smart PLS 4.0 software. The findings reveal a significant influence of Financial Knowledge (X) on Financial Planning (Y). Additionally, Financial Knowledge (X) positively impacts Financial Strategy (Z), which in turn significantly affects Financial Planning (Y). Ultimately, the results demonstrate that Financial Knowledge (X) significantly influences Financial Planning (Y), both directly and indirectly through Financial Strategy (Z). These findings underscore the crucial role of financial knowledge in enhancing financial planning among students.
ظاهرة الإضافة في اللغتین- العربية والبشتوية - (دراسة وصفية)
Authors: عصمت عبدالحنان
Published: December 2024

لاشك أن اللغة العربية هي إحدی اللغات السامية، و‌أن اللغة البشتوية هي إحدی اللغات الآریّة، فمع هذا یوجد الاشتراك والافتراق بینهما في بعض القواعد النحوية، منها ظاهرة الإضافة. الإضافة هي نسبة اسم إلى آخر يسمى أحدهما مضافا والآخر مضافا إليه، و هي من سمات الأسماء في كلتا اللغتین- العربية والبشتوية – وكذا یراعی التذكیر والتأنیث في المضاف في كلتا اللغتین العربية و البشتوية-  ولا يمكن في اللغة العربية أن يتأخر المضاف عن المضاف إلیه، ولكن ینعكس الأسلوب في اللغة البشتوية في هذا وهو أن يتأخر المضاف عن المضاف إلیه، إلا إذا كان المضاف إلیه أحد ضمائر (مې، مو، دې، يې) مثل: (كتاب مې راكړه!، كتاب مو راكړه!، كتاب دې راكړه!، كتاب یې راكړه!) وفي اللغة العربية لا يُنوّن الاسم المضاف ولا یتحلّی بـ (ال)، وإن كان مثنى أو جمع مذكر سالما حذفت نونه، وأما في اللغة البشتوية فلا یوجد(ال) بل یوجد الرابط للمتضایفین وهو حرف الدال (د) فلا بد من هذه الأداة للإضافة إلا إذا كان المضاف إلیه أحد ضمائر(مې، مو، دې، يې) أو یكون مبدوءا بـ (ز) للمتكلم وبـ (س) للمخاطب، فلا تذكر عندئذ أداة الإضافة (د)، والمضاف نكرة دائما والمضاف إليه يأتي معرفة ونكرة، في كلتا اللغتین- العربية والبشتوية- وإذا أضیف الاسم في العربية إلی یاء المتكلم كسر آخره لمناسبة الیاء، وتنقسم الإضافة في اللغة العربية إلی المحضة وإلی غیرالمحضة، فلا یوجد هذا التركیب في اللغة البشتوية؛ ولكن تتشارك االلغتان- العربية والبشتوية- في بعض الأمور الأخری، مثل: الإضافة الملكیة، والبیانية، والظرفية، والتشبیهية من حیث المعنی والدلالة، وغیرذلك.
التفسير قبل الإمام الطبري رحمه الله
Authors: مجاهد الدكتور نصر من الله , الأستاذ ننگیالی قادری
Published: December 2024

هذا بحث موجز حول التفسير، يتركز على المسار التاريخي والمنهجي لعلم التفسير قبل الإمام الطبري -رحمه الله-؛ حیث تحدث عن نشأة التفسير وتاريخه بدءاً من زمن النبي -صلى الله عليه وسلم-، ومروراً بزمن الصحابة والتابعين، وبيّن القضايا المهمة في هذا المجال مثل تفسير الصحابة -رضي الله عنهم- وأهميته، ومصادره، ومميزاته، وهكذا  تفسير التابعين -رضي الله عنهم- وأهميته ومصادره ومميزاته، ثم بيان كيفية تدوين التفسير في هذه المراحل. وتكلم عن أوّل من دوّن التفسير، وإن كان معرفة ذلك أمر شاق؛ لأن ما بأيدينا من المعلومات لا تسعف بأن نجزم بذلك، ثم انتقل البحث إلى مرحلة التفسير من مجرد جمع وسرد الروايات وشرح بعض الألفاظ إلى التفسير النقدي أو الأثري النظري التي سار عليها ابن جرير الطبري -رحمه الله-، لكن الطريقة نفسها تتشكل في تفسير يحيى بن سلام الذي يعتبر مؤسس هذه الطريقة كما صرح به ابن عاشور، ويشهد الواقع أن تفسيره لبنة أساس لتفسير الطبري. ومن ثمّ يتناول البحث تفسير الطبري من عدة نواحي؛ حيث يتم التعريف بشخصية الإمام الطبري وتفسيره، وبيان خصائصه، كما تمت المقارنة في آخر المقالة بين تفسير الطبري والتفاسير الأخرى قبله. والمنهج الذي سار عليه البحث هو المنهج التاريخي، التحليلي والمقارن؛ حيث تمّ جمع المعلومات من أمهات الكتب وتمّ تحليله، ثم إجراء المقارنة بين تفسير الطبري والتفاسير التي سبقته.
乒乓球运动对青少年心理健康发展的影响研究
Authors: 郑文静
Published: December 2024

郑文静
肇庆学院体育与健康学院，肇庆市，广东省，中国
摘要：近些年，我国学者就“如何提高青少年心理健康水平”这一话题展开了广泛而深刻的讨论，其中多数研究表明体育运动对青少年心理健康水平有着积极的促进作用。本文基于文献研究、结合自身的实践教学经验和对各学校学生实际情况的调查研究，总结归纳出乒乓球运动的特点对青少年身心全面发展起到积极作用的几个方面：诸如对其神经发育、心肺功能、意志磨练等。研究结果有利于培养青少年积极向上的乐观精神，协助他们更好地地应对学业压力，实现自我价值。
How to retain website traffic in a generative AI world
Authors: Patterson Laura , Sinex Jacqueline
Published: December 2024

Gartner predicts that generative AI is becoming a substitute for search engines leading to a 25 per cent drop in search engine volume. We live in a digital world, and as such, most organisations rely on search to drive website traffic and ultimately sales. How is search changing? What are the implications and benefits of generative AI in understanding user intent? What can organisations start doing now to retain and increase website traffic in a generative AI world? This paper addresses these questions.