bluuebunny/crossref_metadata_2025 huggingface dataset:
PREDIKSI KELULUSAN MAHASISWA PROGRAM STUDI MATEMATIKA UNIVERSITAS UDAYANA MENGGUNAKAN BACKPROPAGATION NEURAL NETWORK
Authors: NUR IHSAN MUHAMMAD RIZKI , GANDHIADI G.K. , HARINI LUH PUTU IDA
Published: September 2023

Based on the rules of the BAN-PT Study Program Accreditation Instrument 4.0 (IAPS 4.0), one of the study program accreditation assessment indicators is the percentage of students who graduate on time. The percentage of Udayana University Mathematics Study Program students who graduated on time during the graduation period from 2002 to 2019 was 52.5%. It can be seen that many students fail to complete their studies on time, which has an impact on the study program accreditation assessment. Based on these problems, this study aims to help academics increase the percentage of Udayana University Mathematics Study Program graduates by predicting the graduation of mathematics study program students using the backpropagation neural network method. This study uses data on alumni of students of the 2002-2017 mathematics study program. With the BNN 5-3-1 architecture, the predicted results of graduation for students of the Udayana University mathematics study program are 73%.
GAMBARAN KASUS PENYAKIT GINJAL KRONIK DENGAN ANEMIA DI RUMAH SAKIT UMUM PUSAT SANGLAH TAHUN 2018 DAN 2019
Authors: Saraswati Putu Putri Titamia , Wiradewi Lestari Anak Agung , Herawati Sianny , Herawati Sianny
Published: August 2023

Penyakit Ginjal kronik (PGK) dapat menyebabkan beberapa komplikasi seperti hipertensi, anemia, asidosis, albuminuria, dan depresi. Anemia memiliki prevalensi yang cukup tinggi sebagai komplikasi dari PGK. Penelitian ini memiliki tujuan untuk mengetahui gambaran kasus penyakit ginjal kronik dengan anemia di Rumah Sakit Umum Pusat Sanglah tahun 2018 dan 2019. Penelitian ini menggunakan metode deskriptif dan studi potong lintang. Sampel dipilih berdasarkan kriteria inklusi dan eksklusi. Dalam analisa data digunakan software SPSS guna mendapatkan gambaran kasus penyakit ginjal kronik dengan anemia berdasarkan jenis kelamin, usia, tempat tinggal, derajat anemia, dan morfologi anemia. Hasil penelitian menunjukkan kasus penyakit ginjal kronik dengan anemia di RSUP Sanglah tahun 2018 dan 2019 terbanyak dialami oleh laki-laki (71,6%) dengan rentang usia terbanyak pada usia 46-55 (lansia awal) sebesar 34,6% dan sebagian besar penderita PGK dengan anemia bertempat tinggal di kota Denpasar yaitu sebesar 39,5%. Derajat anemia yang tampak pada penderita PGK di RSUP Sanglah tahun 2018 dan 2019 sebagian besar berupa anemia derajat sedang (61,7%), dengan tampilan morfologi anemia yang paling banyak berupa anemia normokromik normositer sebesar 50,6%.

Kata kunci :  penyakit ginjal kronik, derajat anemia, morfologi anemia
PREVALENCE OF EXTENDED SPECTRUM BETA LACTAMASE (ESBL) PRODUCING Escherichia coli AND Klebsiella pneumoniae BACTERIA ISOLATED FROM PNEUMONIA PATIENTS IN SANGLAH GENERAL HOSPITAL FOR PERIOD TIME 2019-2020
Authors: Manuaba Ida Ayu Santhi Pertiwi , Iswari Ida Sri , Pinatih Komang Januartha Putra
Published: August 2023

Pneumonia infection is the sixth highest cause of death in general and the highest cause of death in infection cases, recorded as much as 2.1% of the pathogens that cause pneumonia infection is ESBL-producing bacteria. In general, Escherichia coli (E.coli) and Klebsiella pneumoniae (K.pneumoniae) are the most common bacteria found to be ESBL-producing bacteria. The aims of this study is to discover the prevalence of ESBL-producing in Escherchia coli and Klebsiella pneumoniae bacteria isolated from pneumonia patients at Sanglah General Hospital in 2019-2020 period of time. Method of this study is a cross-sectional descriptive study with a retrospective cross-sectional study approach. Data were taken retrospectively from the register database of the Clinical Microbiology Installation in Sanglah General Hospital. Sample for this research was derived from the results of antibiotics sensitivity tests on sputum isolated from patients with pneumonia infection. The prevalence of ESBL-producing Escherichia coli bacteria 93.3% was found higher than Klebsiella pneumoniae bacteria 69.2%. The highest finding was recorded in male patients and 15-64 years old. Based on the highest number of patients clinical diagnosis, it is found to be pneumonia in Escherichia coli and CAP in Klebsiella pneumoniae. The highest rates of patients are coming from Emergency Room. The result of antibiotic sensitivity test on Escherichia coli and Klebsiella pneumoniae producing ESBL were found the highest antibiotic sensitivity rates on ertapenem, meropenem, amikacin and tigecycline.

Keywords : Escherichia coli, Klebsiella pneumoniae, ESBL, Pneumonia
EPIDEMIOLOGI PENDERITA CELAH BIBIR DAN LANGIT- LANGIT DI RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR TAHUN 2016-2019
Authors: Kristiantini Ni Kadek Pebri , Hamid Agus Roy Rusly Hariantana , Sanjaya I Gusti Putu Hendra , Adnyana I Made Suka
Published: August 2023

ABSTRAK

Celah bibir dan langit- langit merupakan kelainan kongenital pada wajah, berupa celah bibir, gusi, dan langit-langit. Kelainan kongenital ini berdampak tidak baik bagi psikologis maupun psikososial pasien dan menjadi beban sosioekonomis tambahan akibat terganggunya estetik wajah, fonotik, mastikasi, deglutisi dan okulasi mental.Tujuan dari penelitian ini adalah untuk mengetahui epidemiologi penderita celah bibir dan langit-langit yang teregister di RSUP Sanglah. Penelitian ini merupakan penelitian cross sectional dengan jenis penelitian deskriptif retrospektif. Data diambil dengan metode total sampling yang mana data penelitian bersumber dari data rekam medis pasien penderita celah bibir dan langit-langit di RSUP Sanglah tahun 2016-2019. Hasil penelitian didapatkan sejumlah 140 rekam medis dengan kategori pasien yang datang ke RSUP Sanglah terbanyak pada rentang usia 1-5 tahun dan sebagian besar  berasal dari kota Denpasar yaitu sebanyak 39 kasus (27,9%) dengan sebagian besar berjenis kelamin perempuan yaitu sejumlah 76 kasus (54,3%), dan untuk tipe celah langit-langit lebih dominan terjadi pada perempuan yaitu sebanyak 45 kasus (64,3%), Celah bibir dominan terjadi pada laki-laki yaitu sebanyak 10 kasus (55,6%), celah bibir dan langit-langit lebih dominan terjadi pada laki-laki yaitu sebanyak 39 kasus (55,8%) dan berdasarkan lokasinya, celah langit-langit lebih banyak ditemukan yaitu sebanyak 70 kasus (50%).

Kata Kunci: Celah bibir dan langit-langit, umur, jenis kelamin, daerah asal
KARAKTERISTIK PASIEN KANKER KOLOREKTAL DI RUMAH SAKIT UMUM PUSAT SANGLAH TAHUN 2017
Authors: Pranata Anak Agung Ngurah Satya , Dewi Ni Nyoman Ayu , Surudarma I Wayan , Sumadi I Wayan Juli
Published: August 2023

ABSTRAK

 

Kanker kolorektal (Colorectal Cancer/CRC) menempati urutan ketiga kanker dengan prevalensi tertinggi. Studi ini bertujuan memahami karakteristik pasien kanker kolorektal di Rumah Sakit Umum Pusat (RSUP) Sanglah Tahun 2017. Penelitian ini menggunakan rancangan penelitian deskriptif potong lintang. Data yang digunakan diambil dari rekam medis pasien kanker kolorektal yang tersimpan di Instalasi Patologi Anatomi RSUP Sanglah. Kasus CRC yang didapatkan sebanyak 44 kasus; dari 44 kasus tersebut didapatkan data usia termuda yang menderita CRC adalah 23 tahun dan tertua adalah 80 tahun, dengan persentase lebih besar terjadi pada kelompok usia >50 tahun dibandingkan dengan kelompok usia <50 tahun ((n=32 (73%) vs. n=12 (27%)). Penderita CRC lebih banyak pada laki-laki dibandingkan dengan perempuan dengan rasio 25:19. Berdasarkan diferensiasi sel diperoleh 1 sampel (2%) dengan well-differentiated, 29 sampel (66%) dengan moderate-differentiated dan 5 sampel (11%) dengan poorly-differentiated CRC. Lokasi tumor yang paling banyak ditemukan adalah pada rektosigmoid sebanyak 11 sampel (25%) yang diikuti pada rektum sebanyak 9 sampel (20,5%). Penelitian ini diharapkan dapat memberikan kontribusi terhadap data dasar CRC di Bali. Penelitian lebih lanjut dibutuhkan untuk menganalisis hubungan antara variabel karakteristik dengan respon terapi dan prognosis sehingga dapat membantu dalam manajemen CRC.

 

Kata kunci : Kanker Kolorektal, Usia, Jenis kelamin, Diferensiasi Sel
HUBUNGAN ASUPAN TOMAT TERHADAP TEKANAN DARAH PADA DEWASA TUA
Authors: Novitasari Ni Made Winda , Wiryanthini Ida Ayu Dewi , Sutadarma I Wayan Gede
Published: August 2023

ABSTRAK

 

Di era-globalisasi ini terdapat banyak jenis penyakit degeneratif, salah satunya adalah hipertensi. Hipertensi adalah kondisi dimana terjadinya peningkatan pada dinding pembuluh darah arteri dalam jangka waktu yang lama. Penanganan secara non-farmakologis pada hipertensi dapat berupa mengatur perilaku hidup dengan lebih sehat seperti meningkatkan konsumsi buah dan sayur. Karotenoid, kalium, serat, dan asam lemak ?3 adalah zat gizi yang dapat mencegah hipertensi. Likopen adalah salah satu karotenoid yang terdapat dalam makanan. Penelitian ini menggunakan metode pendekatan potong lintang dengan total 85 sampel. Pemeriksaan tekanan darah dilakukan kepada sampel yang memenuhi kriteria inklusi dan untuk mengetahui jumlah konsumsi asupan tomatnya diperoleh menggunakan formulir semi kuantitatif Food Frequency Questionnaire. Pada penelitian ini rerata responden mengkonsumsi tomat sebanyak 122,44 g/bulan, dengan  rerata tekanan darah sistolik 120,74 mmHg, rerata tekanan diastolik 75,07 mmHg. Setelah dilakukan uji normalitas didapatkan nilai p sebesar 0,0001 yang berarti tidak berdistribusi dengan normal pada masing-masing variabel. Pada uji statistik penelitian ini dengan korelasi spearman diperoleh nilai p antara tekanan darah sistolik dengan asupan tomat 0,000 dan nilai r -0,557 yang berarti asupan tomat memiliki hubungan tidak searah yang sedang terhadap tekanan darah sistolik, sedangkan tekanan darah diastolik dan asupan tomat didapatkan nilai p 0,003 dan r -0,314 yang berarti asupan tomat meniliki hubungan tidak searah yang lemah terhadap tekanan darah diastolik.

Kata Kunci: Likopen, tomat, tekanan darah.
EFEK EKSTRAK METANOL DAUN SIRSAK (Annona muricata) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI Salmonella typhi SECARA IN VITRO
Authors: PN Pramadya , MA Hendrayana
Published: August 2023

Salmonella typhi merupakan penyebab utama penyakit demam typhoid. Masalah yang kini dihadapi dari berbagai penyakit infeksi adalah resistensi bakteri terhadap antibiotik. Pengembangan suatu alternatif pengobatan yang tidak menyebabkan efek samping perlu dilakukan. Salah satu tanaman yang telah lama dimanfaatkan sebagai obat tradisional adalah daun sirsak. Kandungan flavonoid, steroid, alkaloid, saponin dan tanin yang dilaporkan pada daun tanaman sirsak (Annona muricata) berkontribusi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui efek antibakteri dengan mengukur zona hambat yang diinduksi oleh ekstrak methanol daun sirsak pada bakteri Salmonella typhi secara in vitro. Penelitian ini merupakan penelitian eksperimental laboratorium dengan rancangan penelitian posttest only control design dengan metode difusi agar (Kirby-Bauer). Studi ini menggunakan daun sirsak yang diekstraksi dengan metode maserasi dengan menggunakan pelarut metanol. Ekstrak metanol daun sirsak dengan konsentrasi larutan 50mg/mL, 100mg/mL, 200mg/mL dan 400mg/mL yang diuji pada bakteri S. typhi secara in vitro. Uji ekstrak secara in vitro pada bakteri S. typhi memperoleh hasil, ekstrak metanol daun sirsak tidak dapat menghambat pertumbuhan bakteri S. typhi secara in vitro. Terdapat beberapa faktor yang tidak dapat dikontrol yang mempengaruhi hasil dari penelitian ini seperti, jenis bakteri, lingkungan tempat tanaman berasal dan efektifitas ekstrak. Diperlukan penelitian lebih lanjut untuk uji antibakteri ekstrak methanol daun sirsak dengan konsentrasi larutan yang berbeda, untuk mengetahui konsentrasi yang dapat memberikan efek secara in vitro pada bakteri S. typhi.

Kata kunci: Salmonella typhi, ekstrak daun sirsak, antibakteri
POTENSI EKSTRAK DAUN KEMANGI (OCIMUM SANCTUM L.) DAN KUNYIT (CURCUMA LONGA L.) TERHADAP TERAPI KANKER KOLOREKTAL
Authors: Dewi Itta Sandi Lesmana , Pamungkas Kadek Mercu Narapati , Risha Kundalini Ida Ayu T , Mariadi I Ketut
Published: August 2023

ABSTRAK Latar Belakang: Kanker kolorektal menduduki posisi ketiga kanker tersering dan posisi keempat kanker yang paling sering menyebabkan kematian diseluruh dunia yaitu sekitar 700.000 kematian setiap tahunnya. Penyakit ini merupakan salah satu keganasan saluran pencernaan yang terbentuk melalui berbagai macam faktor seperti faktor genetik dan lingkungan. Penatalaksanaan kanker kolorektal hingga saat ini dilakukan dengan terapi operasi dan terapi adjuvan yang memiliki banyak efek samping dan mahal bagi sebagian besar orang. Tujuan: Tujuan dibuatnya literature review ini yaitu untuk menemukan modalitas terapi penyakit kanker kolorektal. Metode: Literature review ini disusun menggunakan metode kajian pustaka dengan mengumpulkan sumber dari literatur ilmiah yang valid seperti PubMed dan Google Scholar. Penulis menggunakan kata kunci colorectal cancer, curcumin, Ocimum sanctum L., Curcuma longa Linn., basil, dan tumeric serta logika Boolean “AND” untuk mendapatkan jurnal ilmiah internasional yang spesifik. Pembahasan: Kurkumin dalam Curcuma longa L. dapat menurunkan proliferasi sel kanker kolorektal, merangsang terjadinya apoptosis sel kanker kolorektal, menurunkan metastasis, dan sebagai antiinflamasi. Flavonoid vicenin-2 yang terkandung dalam Ocimum sanctum L. mampu menghambat proliferasi dan menginduksi terjadinya apoptosis sel kanker kolorektal. Zat-zat penting yang terdapat di dalam daun Ocimum sanctum L. diekstraksi melalui beberapa tahapan seperti halnya kurkumin dalam Curcuma longa L. Kesimpulan: Kombinasi ekstrak daun kemangi dan kunyit memiliki potensi sebagai terapi kanker kolorektal. Saran: Penulis menyarankan untuk diadakan penelitan lebih lanjut terkait dosis dan efek samping yang dapat ditimbulkan. Kata kunci : kanker kolorektal., kurkumin., vicenin-2
HUBUNGAN ANTARA EKSPRESI TELOMERASE REVERSE TRANSCRIPTASE (TERT) DENGAN BERBAGAI PARAMETER KLINIKOPATOLOGIS AGRESIVITAS KARSINOMA TIROID PAPILER KLASIK DI RSUP SANGLAH DENPASAR
Authors: Santosa Hilda
Published: August 2023

Karsinoma Tiroid Papiler (KTP) merupakan keganasan tiroid tersering di seluruh dunia. Sebagian besar KTP memiliki prognosis baik, sekitar 10% kasus menunjukkan gambaran klinikopatologis agresif, dan sebagian terkait mutasi promoter Telomerase Reverse Transcriptase (TERT). Tujuan penelitian ini adalah membuktikan hubungan antara ekspresi TERT dengan berbagai parameter klinikopatologis agresivitas KTP klasik di RSUP Sanglah Denpasar. Penelitian ini menggunakan rancangan analitik potong lintang. Sampel adalah semua penderita KTP klasik yang dilakukan pemeriksaan histopatologi di Laboratorium Patologi Anatomi RSUP Sanglah tahun 2017-2019 dengan besar sampel 43. Ekspresi TERT dinilai dengan pemeriksaan imunohistokimia, interpretasi menggunakan H-score. Hubungan ekspresi TERT dinilai pada parameter agresivitas, usia, ukuran tumor, perluasan ekstratiroid, LVI, metastasis KGB regional,. Dianalisis dengan uji Chi-square dengan nilai kemaknaan p<0,05. Hasil penelitian didapatkan hubungan yang signifikan antara ekspresi TERT dengan agresivitas KTP klasik (p=0,041). Terdapat hubungan yang signifikan pula antara ekspresi TERT dengan parameter perluasan ekstratiroid (p=0,010), dan metastasis KGB (p=0,036), namun tidak terdapat hubungan yang signifikan dengan parameter usia (p=0,202), ukuran tumor (p=0,780), dan LVI (p=0,137). KTP klasik dengan ekspresi TERT tinggi memiliki kemungkinan 1,84 kali lebih besar untuk perluasan ekstratiroid, 2,36 kali lebih besar untuk metastasis KGB, dan 2,53 kali lebih besar untuk menjadi agresif. Sebagai simpulan, terdapat hubungan antara ekspresi TERT dengan agresivitas KTP klasik parameter perluasan ekstratiroid dan metastasis KGB regional. Diharapkan pemeriksaan TERT dipertimbangkan untuk dikerjakan rutin pada KTP klasik disamping dari penilaian faktor-faktor agresivitas klinikopatologi, serta sebagai salah satu penanda prognosis buruk pada KTP klasik dalam memprediksi risiko kekambuhan.Kata kunci : TERT, Karsinoma Tiroid Papiler Klasik, Agresivitas, IHK, Klinikopatologis
PENGARUH EKSTRAK BIJI PEPAYA MUDA (Carica papaya L.) TERHADAP KOPULASI DAN JUMLAH ANAKAN MENCIT (Mus musculus L.)
Authors: Saka Rahayu Ni Wayan , Komang Satriyasa Bagus , Jawi Made , Sucindra Dewi Ni Wayan
Published: August 2023

Latar Belakang: Upaya pemerintah untuk mengatur kepadatan jumlah penduduk adalah dengan menggunakan kontrasepsi. Menurut data BKKBN, penggunaan kontrasepsi pada pria lebih sedikit dibandingkan perempuan. Rendahnya partisipasi pria dalam Keluarga Berencana dikarenakan ketersediaan kontrasepsi pria yang minimal. Kontrasepsi pria bisa didapat dari bahanaalam seperti biji pepaya muda (Carica papaya L.) memiliki kandungan bersifat anti fertilitas. Hasil dan Pembahasan: Penelitian ini menggunakan metode True Experimental Post Test Only Control Group Design. Sampel dibagi dalam 3 kelompok yakni kelompok kontrol (P0), kelompok perlakuan 1 (P1) dan kelompok perlakuan 2 (P2) dengan masing-masing jumlah sampel 10 ekor mencit (Mus Musculus L.) setiap kelompok. Data dianalisis menggunakan SPSS. Ekstrak biji pepaya muda (Carica papaya L.) tidak berpengaruh terhadap kopulasi mencit, didapatkan nilai p 0,342 (p>0,05). Ekstrak biji pepaya muda (Carica papaya L.) berpengaruh signifikan terhadap jumlah anakan mencit (Mus Musculus L.) didapatkan nilai p <0,001. Ekstrak biji papaya muda (Carica papaya L.) berpengaruh signifikan terhadap kategori kehamilan mencit (Mus Musculus L.)  didapatkan nilai p <0,001. Ekstrak biji papaya muda (Carica papaya L.) tidak berpengaruh terhadap kopulasi mencit disebabkan oleh regulasi umpan balik negatif sistem hipotalamus-hipofisis, sehingga hormon testosteron masih dalam kadar normal. Ekstrak biji pepaya muda (Carica papaya L.) berpengaruh terhadap jumlah anakan mencit disebabkan oleh kandungan ekstrak biji pepaya muda (Carica papaya L.) yang bersifat anti fertilitas. Kesimpulan : Ekstrak biji pepaya muda (Carica papaya L.) tidak berpengaruh terhadap kopulasi mencit (Mus Musculus L.) , sedangkan berpengaruh terhadap jumlah anakan mencit (Mus Musculus L.)

Kata kunci : Ekstrak biji pepaya muda, kopulasi mencit, jumlah anakan mencit
PERBEDAAN SELF DIRECTED LEARNING READINESS PADA MAHASISWA TAHUN PERTAMA DAN KETIGA FAKULTAS KEDOKTERAN UNIVERSITAS UDAYANA
Authors: Wibawa Ida Bagus Satriya , Wardani Ni Putu , Diarthini Ni Luh Putu Eka , Damayanti Putu Ayu Asri
Published: August 2023

ABSTRAK

Self Directed Learning (SDL) memiliki kaitan dengan pelaksanaan proses pembelajaran Problem Based Learning (PBL) di Fakultas Kedokteran Universitas Udayana. Konsep belajar ini merupakan metode pembelajaran yang berfokus pada mahasiswa itu sendiri atau student centered learning. Penelitian ini bertujuan untuk mengetahui bagaimana kesiapan mahasiswa dalam metode SDL yang biasa disebut sebagai Self Directed Learning Readiness (SDLR). Penelitian ini bersifat cross-sectional analitic dimana pengambilan sampel dilakukan satu kali dengan menggunakan instrument kuesioner pada mahasiswa Program Studi Sarjana Kedokteran dan Profesi Dokter (PSSKPD) mahasiswa tahun pertama pada penelitian ini yaitu angkatan tahun 2018, dan mahasiswa tahun ketiga yaitu angkatan 2016. Penghitungan jumlah sampel dilakukan melalui total sampling dan terkumpul sebanyak 425 kuesioner, dimana angkatan 2016 sebanyak 205 responden, angkatan 2018 sebanyak 220 responden. Kuesioner yang dipakai memiliki 36 pertanyaan utama dan 3 pertanyaan tambahan, kuesioner memiliki nilai 1-5 (Likert Scale) dimana kuesioner telah di validasi oleh Zulharman (2008). Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan skor  yang signifikan antara masing-masing kelompok angkatan (P > 0.05). Skor SDLR pada angkatan 2016 dengan kategori hasil tinggi memiliki jumlah sampel yang lebih banyak dibandingkan dengan angkatan 2018. Kedua kelompok angkatan masing-masing memperoleh skor SDLR pada 2 kategori yaitu kategori tinggi, dan kategori sedang

Kata Kunci: Independent learning, Self Directed Learning Readiness (SDLR), PBL, Skor SDLR
Assessment of the utilization rate of organic and nitrogenated substrates by the microorganisms in a sequencing batch reactor treating tannery wastewater
Authors:   Programa de Ingeniería Agroindustrial, Universidad Centro-Occidental Lisandro Alvarado Venezuela, Freytez-Boggio Estefania , Márquez-Romance Adriana Mercedes ,   Centro de Investigaciones Hidrológicas y Ambientales, Universidad de Carabobo, Venezuela, Barrazueta-Rojas Sandra Gabriela ,   Escuela Superior Politécnica de Chimborazo (ESPOCH), Ecuador, Guevara-Pérez Edilberto ,   Centro de Investigaciones Hidrológicas y Ambientales, Escuela de Ingeniería Civil, Miembro de la Academia Nacional de Ingeniería y Habitar de Venezuela
Published: September 2023

In this article, the utilization rate of organic and nitrogenous substrates contained in tannery wastewater by a sequential batch reactor is evaluated. Two factorial experimental designs (FEDs) were implemented. FED1 (22) used granular biomass, the aeration sequence (oxic, anaerobic-oxic) and cycle duration (6 and 24 h). FED2 (4 x 3) included suspended biomass, reaction phases (anoxic I, oxic, anoxic II (CND: conventional nitrification-denitrification) and (SND: simultaneous nitrification-denitrification), filling time (fast, slow and in stages). The substrates examined were chemical oxygen demand (COD), ammonium (NH4+-N) and total nitrogen Kjeldahl (TKN). The utilization rates were COD (-100 and -200 mg l-1 h-1) (FED1) and (-48 and -75 mg l-1 h-1) (FED2), being 1.5 to 2 times higher in FED1 than FED2. In TKN (-5 mg l-1 h-1), and NH4+-N (-30 mg l-1 h-1), they were significant in the anoxic I and oxic phases.
Selección y aplicación de funciones Cópula con dependencia en su extremo derecho al análisis de frecuencias conjunto (Q, V) de crecientes anuales
Authors:   Profesor Jubilado de la Universidad Autónoma de San Luis Potosí, México, Campos-Aranda Daniel Francisco
Published: September 2023

través del análisis de frecuencias bivariado del gasto máximo (Q) y el volumen escurrido (V) anuales de las crecientes registradas. Las funciones Cópula (FC) son modelos probabilísticos basados en la dependencia entre Q y V, que establecen fácilmente su distribución bivariada con base en las funciones marginales previamente adoptadas o distribuciones de cualquier tipo, iguales o diferentes. La aplicación de las FC en las estimaciones hidrológicas mostró que un aspecto decisivo en su selección idónea está relacionado con la dependencia en el extremo derecho de los datos ("λ" _U^CFG) y la que tienen ("λ" _U) ciertas FC. Por lo anterior, en este estudio se exponen las FC: t de Student, Gumbel-Hougaard, Clayton Asociada y Joe, que muestran valores de "λ" _U que van en aumento. Se contrastan los valores de "λ" _U contra los "λ" _U^CFG obtenidos en 16 registros reales aleatorios de Q y V, para establecer la aplicabilidad de cada FC citada. Además, se procesa como aplicación numérica el registro de 26 datos de Q y V anuales de las crecientes de entrada a la presa Adolfo López Mateos (Humaya) del estado de Sinaloa, México. Por último, se exponen las conclusiones, las cuales destacan las ventajas de las FC en los análisis de frecuencias bivariados de crecientes.
Estimación de la fracción de cobertura vegetal en maíz a partir de información obtenida con sensores remotos
Authors:   Posgrado en Hidrociencias, Colegio de Postgraduados, Texcoco, Estado de México, México, Muñoz José M. , Bolaños Martín A. ,   Posgrado en Hidrociencias, Colegio de Postgraduados, Texcoco, Estado de México, México, Palacios Enrique ,   Posgrado en Hidrociencias, Colegio de Postgraduados, Texcoco, Estado de México, México, Palacios Luis A. ,   Servicios de Estudios en Ingeniería y Sistemas, S.A. de C.V., Hermosillo, Sonora, México, Salvador José M. ,   Posgrado en Hidrociencias, Colegio de Postgraduados, Texcoco, Estado de México, México
Published: September 2023

La fracción de cobertura vegetal (FCV) es una variable biofísica relacionada con la biomasa, el índice de área foliar y el coeficiente de cultivo, entre otros. Actualmente, con la amplia disponibilidad de imágenes satelitales, es posible estimar la FCV de forma extensiva usando índices de vegetación (IV). No obstante, es importante examinar la relación entre la FCV medida en campo y la estimada con imágenes satelitales para conocer su confiabilidad. El objetivo del presente estudio fue examinar la viabilidad de estimar la FCV utilizando diferentes IV (NDVI, SR, SAVI y MSAVI), calculados mediante información radiométrica e imágenes Landsat 8, y determinar las diferencias que existen al estimar la FCV con ambas fuentes de información. La información radiométrica se levantó en seis parcelas de maíz ubicadas en el municipio de Texcoco, Estado de México. Los resultados mostraron un buen ajuste de los IV calculados con información de campo cuando la FCV fue menor del 60 %. La correlación entre la FCV medida en campo y los índices estimados con imágenes satelitales tuvieron valores de R2 superiores a 0.78, siendo ligeramente mayor en el caso del NDVIL (R2 = 0.89), valor que sugiere un grado aceptable de ajuste. Se concluye que es viable estimar la FCV en un cultivo de maíz empleando imágenes espectrales de Landsat 8. El mejor ajuste entre los IV de campo y los IV calculados con datos de Landsat 8 para las condiciones de este estudio correspondió al NDVI.
Development strategy of Russian metallurgical companies in the new world economic order
Authors: PASHTOVA Lelya G. , ZHIDELEV Nikita A. , LIKHOPOI Aleksandra O.
Published: August 2023

Subject. The article investigates features of modern strategic development of iron and steel plants in the Russian Federation
Objectives. The purpose is to determine the main directions of development strategy of the metallurgical complex in the production of ferrous and non-ferrous metals in Russia to identify further prospects for industry enterprises.
Methods. The study employs methods of scientific cognition, like comparative analysis, synthesis, induction, and deduction. These methods helped to build dynamic and structural models.
Results. We performed the analysis of technological innovation effectiveness in the production process of metallurgical enterprises, identified the main problems of the industry resulting from the crisis situation in the country and the world, and considered issues related to interaction of innovation activity and the use of R&D in the development of the industry. The study unveiled the specifics of the Russian metallurgical industry in the field of export, allocation of funds for the introduction of innovation.
Conclusions. The development strategy of Russian metallurgical industry for the period up to 2030 set benchmarks for the growth of ferrous and non-ferrous metallurgy, however, Russian enterprises need investments in R&D, which, in the future, will entail an increase in the profitability of their products and a more stable position among international competitors in the market.
The prevalence of temporomandibular joint disorder in female students from 17 to 30 years at Taibah University in all colleges
Authors: Nourwail Ibrahim , Alharbi Ammar , Hesham Wael , Talib Kussay , Basalamah Mohammad
Published: September 2023

Objective: This study aimed to assess the prevalence of temporomandibular joint (TMJ) disorder (TMD) and its association with anxiety, college, all-day activities, and stress among female students at Taibah University.
Methods: A cross-sectional observational study was carried out to develop a consensus of female students at Taibah University in all colleges from ages 17 to 30 years. The data were obtained through a questionnaire survey. A Google Drive questionnaire template was used. The questionnaire was sent to the participants through WhatsApp, SMS, and emails.
Results: The study included 205 female students, with the majority of the participants falling between the ages of 17 and 23 years (78%). According to the presented data, 29.3% of participants reported having or presently experiencing issues with their jaw joints. The most prevalent symptom among those reported was a crackling sound (72.4%). Around 43.6% participants said that exercises were the most effective treatment for jaw problems, whereas 40% believed that medications were the most effective treatment. There was a significant correlation between age and having or currently suffering from jaw joint problems (p-value = 0.031).
Conclusion: The current study highlighted the high prevalence of jaw joint problems, which is known as temporomandibular disorders among female university students of different colleges. The current study also reported that there are different factors that might be associated with aggravation and development of the Temporomandibular joint including stress, sleep disturbance, and changes in daily routine.
Analysis of the state and problems of pharmaceutical supply for patients with epidermolysis bullosa
Authors: Sliptsova N. A. , Nazarkina V. M.
Published: September 2023

Aim. To analyze medical technologies (MT) for the treatment of epidermolysis bullosa (EB) and their availability to patients and the healthcare system.
Materials and methods. The study objects were scientific publications, normative legal acts, guidelines (protocols), statistical data, the Orphanet network, official data of the Ministry of Health and the State Enterprise “Medical Procurement of Ukraine”, marketing information. The methods of content analysis, structural and logical, comparison, generalization, marketing analysis were used.
Results. Modern approaches to the classification of types of EB were studied; epidemiological indicators were analyzed; recommendations of clinical protocols were summarized. It has been found that currently there are no available specific MT in the world for the treatment of this severe chronic disease. International clinical guidelines recommend the use of medicines and medical products to relieve symptoms (wound care, reduce pain and itching), prevent secondary pathologies and improve the quality of life of patients with EB. The cost of treating EB depends on the severity of the disease and the patient’s age. The burden of the disease and the impact on the budget are assessed to be high. The state cannot provide 100 % of the need for the necessary medicines and medical products due to budget constraints. The analysis of the national legal framework for providing patients with rare (orphan) diseases, including EB, with the necessary medicines and medical products was carried out. It has been determined that only 9 INNs of the seven groups of medicines recommended by the protocol are included in the National List and can be purchased for budget funds. The annual need, nomenclature and volumes of purchases of drugs for the treatment of EB were studied. According to the State Enterprise “Medical Procurement of Ukraine” in 2023, for patients with EB it is planned to purchase eight groups of medical products for skin and wound care under 20 names in the amount of UAH 119.8 million.
Conclusions. In order to improve approaches to the pharmaceutical provision of patients with EB, it is extremely important to use health technology assessment (HTA) to identify the most effective and economically feasible medicines and medical products.
Adolescência, Saúde Mental e TransLGBQIA+fobia no Ambiente Escolar
Authors: Cavalcante Marina de Almeida , Pereira Alexandre Adalberto
Published: August 2023

Este trabalho tem por objetivo apresentar reflexões iniciais de uma pesquisa de mestrado em desenvolvimento, a qual discutirá sobre a relação entre a saúde mental e a TRANSLGBQIA+fobia em adolescentes, no ambiente escolar. A homofobia é uma manifestação arbitrária, a qual se denomina o outro como contrário, inferior ou anormal. Desse modo, o homossexual é visto - pela norma social - como bizarro, estranho ou extravagante. A escola é um espaço público destinado a promover a cidadania, consequentemente, a função da educação não deve e não pode se restringir apenas a transmissão de conhecimentos. O papel da escola é lutar contra a intolerância e consequentemente reconhecer a igualdade de pessoas trans, gays e lésbicas como sendo uma questão que tem a ver com todos. A partir do levantamento bibliográfico realizado, os resultados foram discutidos a partir das categorias em intersecção: Homofobia e Adoecimento psíquico em adolescentes TRANSLGBQIA+. A partir dos dados encontrados nos estudos, pode-se inferir que a população TRANSLGBQIA+ está mais suscetível ao adoecimento psíquico em função da sua orientação sexual, se comparados com os heterossexuais. Tal adoecimento pode estar relacionado à marginalização que esses grupos sofrem nos diversos ambientes os quais estão inseridos: na família, na escola e na sociedade em geral.
Pengaruh Pemberian Ekstrak Etanol Daun Sisik Naga (Pyrrosia Piloselloides L.) terhadap Penurunan Kadar Kolesterol Total Mencit Hiperkolesterolemia
Authors: Afriyeni Helmice , Putri Nesya Indah , Rizal Rosiana
Published: September 2023

Hiperkolesterolemia merupakan faktor risiko terjadinya penyakit kardiovaskular seperti strok, aterosklerosis dan jantung koroner. Tujuan dari penelitian ini untuk mengetahui pengaruh ekstrak etanol daun sisik naga (Pyrrosia piloselloides L.). Sebanyak 25 ekor mencit putih jantan diinduksi hiperkolesterolemia dengan makanan diet lemak tinggi (MDLT) ±14 hari, mencit dinyatakan hiperkolesterolemia jika kadar kolesterol total (KT) >230mg/dl, kemudian dibagi menjadi 5 kelompok perlakuan yaitu kontrol positif, pembanding (simvastatin), dan kelompok yang diberi ekstrak uji dosis 25, 50, 100 mg/kgBB. Perlakuan diberikan selama 15 hari, pada hari ke 0, 5, 10 dan 15 dilakukan pemeriksaan kadar KT. Data dianalisis dengan Two Way ANOVA dan dilanjutkan dengan uji Duncan. Hasil penelitian menunjukkan dosis ekstrak uji dan waktu berpengaruh signifikan (p<0,05) terhadap penurunan kadar KT mencit. Semua kelompok dosis ekstrak etanol daun sisik naga memberikan efek penurunan KT pada mencit dan nilai persentase penurunannya sebanding dengan kelompok yang diberi simvastatin. Hasil ini menunjukkan ekstrak etanol daun sisik naga berpotensi dalam menurunkan kadar kolesterol total mencit hiperkolesterolemia
Ureum and Creatinine Levels of Kidney Failure Patients Pra and Post Hemodialysis in Jayapura General Hospital Papua
Authors: Sinaga Herlando , Prastyawati Rini , Tompodung Rivie Joan Pretty , Surbakti Beby Syahputra , Sulistianingsih Sulistianingsih
Published: September 2023

Kidney failure is a worldwide health problem seen from the increase in incidence, prevalence, and the level of morbidity. Indonesia is one country with high rates of kidney failure. The purpose of this research was to determine the description of the results of urea and creatinine levels in patients with kidney failure before and after hemodialysis. The population used in this study was all renal failure patients who would carry out hemodialysis at the Jayapura Regional General Hospital (RSUD). The number of samples in this research is 30. The method of examining urea and creatinine used is the photometry method. This research was conducted from 10 May to 10 June 2018. To determine the levels of urea and creatinine before and after hemodialysis, the average value of the results of the examination was calculated and the results of the average urea level before hemodialysis 53.37 mg/dl and the average yield were obtained. Average after hemodialysis 18.83 mg/dl. The results of the average creatinine level of patients before 12.25 mg/dl and the average results after hemodialysis were 43.63 mg/dl. The results of the examination showed that there were no significant differences and that the results remained high. This research concluded that there was no significant difference between the examination of urea and creatinine levels before hemodialysis and after hemodialysis.
Factores de éxito para el desarrollo de la bioeconomía en el Valle del Cauca
Authors: Bruszies Christian Johannes
Published: September 2023

El objetivo del artículo es establecer los componentes de éxito que podrían conducir al desarrollo de la bioe- conomía en Colombia mediante el establecimiento de clústeres de biotecnología. El análisis parte del poten- cial de desarrollo reconocido por la Misión Internacional de Sabios del Gobierno de Colombia basado en un modelo conceptual de factores de éxito. Además, el estudio integra tres enfoques de análisis complementa- rios ampliando la perspectiva del objeto de estudio: 1) análisis espacial enfocado en las políticas públicas, contexto social macroeconómico y características del territorio; 2) análisis estructural, componentes clave del sector biotecnológico; 3) análisis funcional, los requisitos necesarios para la innovación. Estas herramien- tas permiten el análisis de la iniciativa del clúster Sistema Regional de Innovación de la Biotecnología (SRIB) en el Valle del Cauca, Colombia. Finalmente, se propone una hoja de ruta que podría usarse para crear una estrategia de clúster exitosa en el desarrollo de la bioeconomía departamental.
Mediating Role of Environmental Attitude Between Consumers’ Satisfaction and Repeat Purchase of Eco-friendly Petrol in Indonesia
Authors: Widodo Arry , Wahid Nabsiah Abdul
Published: September 2023

Indonesia has serious air pollution. The joint effort between the Indonesian government and PT. To minimise pollution problems, Pertamina has introduced eco-friendly petrol known as Pertamax RON 92, targeted at fourwheel vehicle consumers. This study investigates whether environmental attitude mediates consumers' satisfaction and repeat purchase behaviour in consuming Pertamax. A survey of 469 Pertamax consumers in Jakarta petrol stations confirmed that consumers' satisfaction and repeat purchase behaviour are mediated by environmental attitude. The tests carried out between satisfaction and attitude, perspective, repeat purchase, and satisfaction and repeat purchase also found significant relationships between the variables. The results imply the critical roles played by three variables as displayed from the direct and indirect connections. In other words, consumers purchased Pertamax RON 92 because they are satisfied and have a positive environmental attitude. For future promotion, the focus can be emphasised on the quality of eco-friendly petrol. It influences consumers’ satisfaction and continuous education to enhance consumers' positive attitudes toward the environment. This research describes a caring attitude towards the environment stimulated by consumer satisfaction in consuming green innovative products, which has become a highlight of environmental issues in various parts of the world.
Keywords— Satisfaction; Environmental Attitude; Repeat Purchase; Eco-friendly
Big Data Utilization on Tourism Marketing in Post-Pandemic Recovery Ear: Future Prospect for Indonesia
Authors: Istanto Ismayanti , Ali Hapzi , Siolemba Patiro Shine Pintor , Damarwulan Liza Mumtazah
Published: September 2023

Along with the behaviour changes toward digitalisation in the pandemic, reliable data to manage tourism marketing in Indonesia is needed. The study objectives are to go into detail on the application of big data and identify what kind of data is necessary for tourism marketing based on the previous research. Most studies about big data on tourism marketing come from overseas, with only a few from Indonesian authors. Questions were raised on what big data is used in tourism marketing and what data is needed, mainly for Indonesia. The use of big data and the kind of data for the benefit of tourism marketing in this study has yet to be discovered. The study adopted SLR with the PRISMA approach and continued with bibliometric analysis using VOS Viewers based on keywords and co-occurrence. Scopus is a database source, and 105 articles published from 2002 to 2022 are found. There are six clusters from plotting extensive data application networks. Two forms of big data can be gained to foresee tourism marketing in post-pandemic recovery. The utilisation cluster is the consumer behaviour research, technology operation, social media, future prediction based on network sentiment analysis, and innovation in smart tourism. Data from the tourism industry and non-tourism sector can be utilised. The study implied combining both the tourism and non-tourism sectors as integrated big data in tourism marketing for decision-making in the future.
Keywords— big data; marketing; non-tourism; tourism; utilization
A Literature Review and Conceptual Framework on Corporate Strategic Foresight – What Value Created as a Source of Competitive Advantage in the Automotive Industry
Authors: Purwanto Jaka , Nasution Reza Ashari , Anggoro Yudo
Published: September 2023

Nowadays, the challenge in the automotive industry is more demanding due to the increase in dynamicity and complexity of environmental changes in the external business environment. Under the increasing uncertainty level, companies require a strategic approach to face these challenges. One of the essential techniques used to meet the environmental dynamic is corporate strategic foresight. Hence, it is essential to understand its value creation because the business environment is getting more uncertain and intense competition. However, the investigation of corporate strategic foresight value creation in the automotive industry is limited. This study aims to investigate corporate strategic foresight value creation and attempts to answer the research question of what value is created from corporate strategic foresight as a source of the firm's future competitive advantage in the automotive industry. This study employed a narrative literature review method based on the existing literature as a part of the qualitative study. The result showed a novelty in the conceptual framework of corporate foresight value creation in the automotive industry. It also provides insight into how organizational values are created to enhance the capability to gain competitive advantage, which contributes to practical especially to managerial and practitioners’ automotive industry for a better understanding of corporate strategic foresight.
Keywords— automotive; competitive advantage; corporate strategic foresigh; environmental dynamic; value creation
The Impact of Corporate Governance and Liquidity on Financial Distress with Firm Size as Moderating Variable
Authors: Khaeria Nurul , Kristanti Farida Titik
Published: September 2023

This study aims to check whether corporate administration and liquidity to some degree, affected monetary pain, with firm size going about as a mediator between liquidity and monetary misery. Gender diversity, managerial ownership, institutional ownership, and independent commissioners were used to execute corporate governance in this study. This study's example incorporates 13 property and land organizations that were recorded on the Indonesia Stock Trade somewhere in the range of 2017 and 2021, with a sum of 65 observational data of interest. The logistic regression analytic technique and moderation regression were used in the inquiry. The findings emphasized the concurrent influence of liquidity and corporate governance on financial stress, whereby managerial ownership, institutional ownership, and independent commissioners positively influence financial distress., In contrast, gender diversity and liquidity partially do not. Firm size has no effect on the relationship between liquidity and financial distress.
Keywords—Corporate Governance; Financial Distress; Firm Size; Liquidity
Advancements in Fire Alarm Detection using Computer Vision and Machine Learning: A Literature Review
Authors: M Fadli Ridhani  , Wayan Firdaus Mahmudy
Published: September 2023

Fire is one of the most common and increasing emergencies that threaten public safety and social development. This can cause significant loss of life and damage. Fire detection systems play an important role in the early detection of fires. The purpose of this study is to provide a brief survey of the latest literature in the field, which can provide a foundation for researchers to develop a Fire Alarm Detection System with a Computer Vision and Machine Learning approach. The Computer Vision and Machine Learning approaches are popular and have been extensively studied because the advantages. The main challenges in fire detection systems are high false alarm rates and slow response times. This research presents potentials and emerging trends through Computer Vision and Machine Learning approaches for Fire Alarm Detection Systems in the future, including the selection of input features to the use of appropriate methods and the process flow of Fire Alarm Detection Systems.
Study of the antibacterial activity of Malva Neglegta
Authors: Mutlak Jasim Thamer
Published: August 2023

Different extract of Malva neglecta were investigated for their antibacterial against Streptococcus pneumonia, Staphylococcus. aureus. Haemophilus. Influenza. Moraxella,. catatahhs. Almost all extract produced significants antibacterial activity against all microorganisim the in comparisom with Gentamicin sulphate.Petrolium.ether was more effective than the other extract . The flavonoids was separated on silica gel thin layer chromatography and responsible for this activity the study determined that t antibacterial action is related to flavonoid.
Correlation between diabetes mellitus and hyperlipidemia in patients with ischemic heart disease
Authors: M.Al-Janabi Jasim , Sharif Abdulla Mohammed , S. AL-Hindi Aseel
Published: August 2023

Diabetic is commonly associated with abnormalities in plasma lipids and lipoproteins levels .In particulars, diabetes mellitus, usually presents with concomitant elevations in the plasma triglycerides levels and reductions in plasma HDL-cholesterol concentration. These abnormalities certainly play a role in the increased risk for cardiovascular disease, particularly ischemic heart disease (IHD). Blood samples were taken from (150) healthy control subjects (86 male and 64 females), (150) patients suffer from previous signs of IHD (84 males and 66 females) were involved in this study. The blood samples from these groups were analyzed for measuring serum total cholesterol, triglycerides, phospholipids, low-density lipoprotein, very low density lipoprotein, high- density lipoprotein and fasting blood glucose .All control subjects have a normal fasting blood glucose, normal resting electrocardiograph, blood pressure and serum lipids. Diabetics have been shown to have high levels of serum lipids than non diabetics and it also important role in the occurrence ofIHD particularly in hyperlipidemic patients.
Recent Developments in Aviation Law
Authors: Wakim Brittany C.
Published: September 2023

Recent Developments in Aviation Law addresses developments in aviation law from January 2022 through December 2022. This submission focuses on certain cases in the area of aviation law that are expected to have a significant impact upon, and ramifications for, the industry going forward such as: (1) the Federal Aviation Act and Federal Aviation Regulations; (2) the Air Carrier Access Act; (3) the General Aviation Revitalization Act; (4) the Airline Deregulation Act; (5) the Montreal and Warsaw Conventions; (6) the Federal Tort Claims Act; and (7) the Death on the High Seas Act. Finally, this submission also discusses recent developments relating to the Federal Aviation Administration’s regulations for unmanned aircraft, as well as the potential impact of recent developments in the application of the Feres Doctrine.