bluuebunny/crossref_metadata_2025 huggingface dataset:
Optical Properties of Nano-circuits for Metallic and Non-Metallic Nanoparticles
Authors: Liaqat Maryam
Published: April 2022

Optical properties of the nanoparticles can be studied theoretically by using the lumped electronic components. The particles having >0 behaved as capacitor whereas for  <0 had inductor properties on the other hand the electric field perpendicular to the components then the properties of series combinations dominates and vice versa. A first principles electronic structure based method is presented to determine the equivalent circuit representations of nanostructured physical systems at optical frequencies, via a mapping of the effective permittivity calculated for a lattice of physical nano-elements using density functional theory to that calculated for a lattice of impedances using circuit theory. Specifically, it is shown that silicon nanowires and carbon nanotubes can be represented as series combinations of inductance, capacitance and resistance. It is anticipated that the generality of this approach will allow for an alternate description of physical systems at optical frequencies, and in the realization of novel opto and nanoelectronic devices, including negative refractive index materials.
An Efficient Swarm based Feature Selection Technique using Random Weight Neural Network
Authors: Manshah Muhammad , Aamir Raza Rana , Ajmal Saadia , Pasha Urooj , Ali Asghar
Published: April 2022

Feature selection (FS) is one of the most important pre-processing tasks in machine learning (ML) and data mining, that selects optimum features by eliminating noisy and irrelevant features from the data; to improve the generalization ability of a learning model (i.e., classifier). During the classification process, data with high dimensional feature space requires different optimization techniques to obtain better predictive performance. In this paper we present a swarm intelligence based technique called binary artificial bee colony (Binary-ABC) to obtain optimum feature subset. Different binary and multiclass datasets are utilized to evaluate the performance of our proposed technique. Experimental results show that our technique provides better generalization ability with random weight neural network (RWNN), when compare with other ML classifiers.
The Anti-leukemic Potential of Cyclea peltata as Validated by Phytochemical and Cell Line Studies
Authors: Devidas Une Hemant , Bansidas Bhagure Lalita
Published: April 2022

Hematological malignancies for a very large percentage of cancers occurring the world over and lead to a very large number of deaths each year. It is not just the disease but also the currently available cure which are equally responsible for the side effects and discomfort experienced by the patients. The side effects of the current chemotherapeutic agents' available range from mouth ulcers, diarrhea, temporary hair loss, rashes, nausea, vomiting, and fatigue to low blood cell counts, increased risk of infections, graft versus host disease, tumor lysis syndrome, differentiation syndrome, and difficulty in conceiving. Due to these myriad side effects researchers and on a continuous lookout for newer treatment alternatives. For most developing countries one of the most attractive options is offered by herbals or plant-based medicines. One such herb is Cyclea peltata. It is a climbing shrub found aplenty in southern and eastern India. It has been used traditionally to cure lots of minor ailments. This paper explores the possibility of using the root extract for the treatment of leukemia. To do this, the extracts of the roots were prepared in different organic solvents to ensure complete extraction of all phytoconstituents fractions. The extracts were then tested on 3 different human cell lines. The potential cause of the antileukemic potential of the plant was also hypothesized and proven by carrying out antioxidant studies using the DPPH free radical scavenging assay. The probable active constituents were identified using the liquid chromatography-mass spectrometry assessment, wherein the responsible fractions were successfully identified. The studies showed that the alkaloid and phenolic phytoconstituents were responsible for the antileukemic potential via their antioxidant activity. This lays down the groundwork of offering a new and safer treatment option that could be further explored to be made into one having actual clinical outreach.
Effect of Amlodipine in Proliferative Retinopathy: Biochemical Estimation and Zebrafish (Danio rerio) Modeling
Authors: Nanda Ashirbad , Aparna Sai , Sahoo Rudra Narayan , Pramanik Arunima , Satpathy Bhargab , Mallick Subrata , Das Debajyoti , Patri Manorama
Published: April 2022

Proliferative retinopathy is described as a progressive neovascularization in the inner surface of the retina or vitreous, which subsequently threatens vision by causing retinal detachment or vitreous hemorrhage. Reactive oxygen species generation and its related vasoproliferative factor up regulation play a major role in progression of the disease. The present study focuses on Carr induced reactive species generation with its related vasoproliferative factor up regulation and ameliorative activity of AML. Biochemical estimation of catalase, lipid peroxidation, hypoxia inducing factor (HIF-1α) and guanyl-s-transferase (GST) were done. AML treated group showed significant increase in catalase enzyme, guanyl-s-transferase and significantly reduced the lipid peroxidation. Western blotting assay showed a significant decrease in HIF-1α in AML treated group. The progression of PR alters the endogenous cell signalling thus causing havoc in retinal cells. Therefore, it could be hypothesized that use of AML can be a new detection method for therapeutic strategies to prevent blindness in PR.
VDR Gene Polymorphism and Rheumatoid Arthritis in Egyptian patients
Authors: El-Sayed Mahmoud Samar , El-Shafey Abeer M. , Keshta A.T.
Published: April 2022

Background and objective: Rheumatoid arthritis (RA) is a systemic autoimmune multifactorial complicated disease that is related to widespread morbidity and mortality. The current study aimed to study the relation between vitamin D receptor (VDR) gene polymorphism rs731236 (TaqI) and rs7975232 (ApaI) and RA susceptibility. Subjects, Materials and Methods: This study included 50 individuals were divided into two groups: Healthy volunteers group (10) and RA group (40) from Rheumatology and Rehabilitation Department, Faculty of Medicine, Zagazig university hospitals. DNA was extracted from whole blood for all samples, and PCR was amplified using specific primers rs 731236 (TaqI) and rs 7975232 (ApaI) VDR restriction digestion was carried out for TaqI and ApaI genotyping, respectively. Results: There were non-significant difference in VDR gene polymorphism between RA patients & control subjects. Conclusion: TaqI is more specific than ApaI but Taq1 and Apa1 gene polymorphism not used as a diagnostic marker for RA disease, so there is no relation between VDR and RA.
In silico Inhibition studies of constituents of Abutilon indicum on Xanthine oxidase
Authors: M Guruvigneshwari , Bharathi R Vijaya , R Radha , B Sooriyapriya
Published: April 2022

Objective: To find out the xanthine oxidase inhibitory potential of constituents reported from the Abutilon indicum through in silico studies as there is traditional claim supporting the use of this plant in treating gout. Method: The 33 constituents of Abutilon indicum were chosen for the study and their drug likeness were read using online application SwissADME. Molecular docking studies were done in Autodock version 1.5.6. The docked samples were viewed using Molegro Molecular Viewer 2.5.0. and Pymol. Allopurinol was used as standard to compare the docking scores of the plant constituents. Results: All the 33 compounds (A1-A33) exhibited drug likeness. Good binding energies were observed for 19 constituents against 3AX7 protein. 6 compounds such as luteolin, beta-amyrin,1-lycoperodine, chrysoeriol, quercetin and flavone possessed binding energies greater than 8 and good inhibition constant values. Conclusion: The constituents of Abutilon indicum has good xanthine oxidase inhibiting potential and can further be developed into a drug candidate against gout.
Circadian clocks
Authors: Creux Nicky M. , Dantas Luiza Lane de Barros , Prusty Manas Ranjan
Published: April 2022

Hosted by New Phytologist Editor, Elena Kramer, Harvard University

Featuring:

- Nicky M. Creux, author of [Flower orientation influences floral temperature, pollinator visits and plant fitness](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17627)

- Luíza Lane de Barros Dantas, author of [Field microenvironments regulate crop diel transcript and metabolite rhythms](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17650)

- Manas Prusty, author of [Genetic loci mediating circadian clock output plasticity and crop productivity under barley](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17284)
Prediksi Pergerakan Harga Saham Pada Sektor Farmasi Menggunakan Algoritma Long Short-Term Memory
Authors: Agusta Ardiyan , Ernawati Iin , Muliawati Anita
Published: April 2022

Saham adalah dokumen berharga sebagai bukti kepemilikan bagian suatu perusahaan. Harga saham bersifat fluktuatif dikarenakan berbagai faktor internal dan eksternal perusahaan. Di tengah pandemi Covid-19 yang terjadi sangat berdampak bagi harga saham tiap perusahaan, salah satunya perusahaan yang bergerak di bidang farmasi. Perusahaan farmasi diperkirakan mengalami penurunan saham karena pandemi, tetapi perusahaan juga bisa mendapatkan kenaikan harga saham karena makin banyaknya penjualan dan riset obat bagi masyarakat. Dengan adanya perubahan harga saham yang tak menentu ini maka diperlukan suatu sistem untuk memprediksi pergerakan harga saham. Dalam memprediksi harga saham, penelitian ini menggunakan algoritma Long Short-Term Memory, dimana data perusahan Kalbe Farma dipilih sebagai salah satu perusahan farmasi. Data yang telah diperoleh dari situs yahoo finance akan dilakukan pengolahan data dengan pengujian pada model yang dibentuk dengan menggunakan paramater hidden layer, units serta variasi epoch dan batch size yang menghasilkan hasil prediksi harga saham dengan rerata nilai RMSE 27.310.
Klasifikasi Kepuasan Pengguna Layanan Aplikasi Shopee Menggunakan Metode Decision Tree C4.5
Authors: Haekal Ballya Vicky , Ernawati Iin , Chamidah Nurul
Published: April 2022

Seiring perkembangan teknologi, Saat ini sudah banyak sekali layanan aplikasi perdagangan online yang digunakan oleh masyarakat. Salah satu layanan aplikasi yang sering digunakan masyarakat adalah Shopee. Semakin banyak pengguna yang menggunakan aplikasi tersebut, tingkat kepuasan tiap pengguna pun semakin beragam. Dalam menganalisis tingkat kepuasan pengguna layanan aplikasi shopee, penelitian ini menggunakan data yang diambil dari kuesioner yang telah disebarkan dalam bentuk google form. Kuesioner tersebut disebarkan melalui beberapa media sosial seperti Twitter, Instagram, WhatsApp dan Shopee dengan total jumlah data yakni 184 data yang akhirnya menjadi 171 data setelah dilakukan cleaning data. Dari berbagai algoritma klasifikasi yang ada, penelitian ini menggunakan algoritma Decision Tree C4.5 sebagai metode klasifikasinya. Dengan pembagian data sebesar 80% untuk data latih dan 20% untuk data uji. Hasil yang diperoleh pada penelitian ini terdapat nilai Accuracy sebesar 97%, nilai Recall sebesar 96.9%, nilai Precision sebesar 100% untuk Class “Ya” dan 66.6% untuk Class “Tidak”.
Pendampingan Proyek Kemanusiaan di Wilayah Kota Bima melalui Program Pejuang Muda Kementerian Sosial
Authors: Fauziah Ade Fitri , Syarifuddin Syarifuddin , Husna Aida Nabilah Army , Sahlaludin Muhamad , Finariyah Finariyah , Yasmin Haritsah Shofiyah , Hendarwan Jhordi , Tricilia Marzela , Muzaki Mukhlash , Pardi Pardi , Navassa Shania Putri
Published: April 2022

Program Pejuang Muda merupakan program kampus merdeka yang diinisiasi oleh Kementerian Sosial, Kementerian Pendidikan dan Kebudayaan, dan Kementerian Agama, dengan melibatkan mahasiswa sebagai pelaksana kegiatan dilapangan. Tujuan dari program Pejuang Muda adalah menverifikasi dan validitas data DTKS (Data Terpadu Kesejahteraan Sosial), membentuk team based project, dan membangun kewirausahaan sosial guna membangkitkan ekonomi kreatif. Team Pejuang Muda Kota Bima sebanyak 10 orang, yang berasal dari beberapa perguruan tinggi, dan hasilnya adalah dengan mengonversi hasil kegiatan program Pejuang Muda ke dalam 20 sks matakuliah. Sasaran program Pejuang Muda ini adalah masyarakat Kota Bima yang terdata dalam DTKS. Pelaksanaan Program Pejuang Muda di Kota Bima berlangsung setelah proses pembelakalan. Kegiatan verivikasi dan validasi DTKS yang terealisasi adalah sebanyak 6.053 data, Kemudian team based project melakukan pemetaan masalah melalui observasi yang dilakukan pada saat melakukan verifikasi dan validasi data, kemudian berkoordinasi dengan BAPPEDA Kota Bima, melakukan penyusunan proposal, dan konsultasi dan meeting online serta offline dengan mentor, serta sosialisasi program Bank Sampah Sarae Maraso.
Rate of secondary HLH and performance of H-score in patients with severe COVID-19
Authors: Alam Fiaz , Becetti Karima , Alamlih Laith , Cackamvalli Priyanka , Veettil Safna , Awadh Basem , Ibrahim Mohamed , Al Emadi Samar
Published: April 2022

Background: Severe COVID-19 is thought to be caused by immune overdrive and cytokine storm. One of the cytokine storm syndromes frequently induced by infections is secondary hemophagocytic lymphohistiocytosis (HLH) which can be assessed using H-score. In this study, we aimed to evaluate the rate of patients with COVID-19 who meet HLH criteria based on H-score and the association of H-score with poor outcomes.

Methods: In a prospective cohort study of 19 patients with COVID-19 requiring ICU stay from March to May, 2020, we collected demographic and clinical data that focused on H-score's variables and COVID-19 outcomes. H-score ≥ 169 was used to determine the percentage of patients who met the HLH criteria. Mann-Whitney, Kruskal-Wallis, and Spearman rho tests and multiple regression analyses were carried out to evaluate the associated factors. The optimal H-score cut-off to predict poor COVID-19 outcome (need for intubation ± ECMO) was determined using receiver operating characteristic (ROC) analysis.

Results: In 669 patients with severe COVID-19 with a mean ± SD age of 50.3 ± 12.8 years, which comprised 95% men; 66% required intubation, 4% ECMO, and 16% died. Only 2% had an H-score ≥ 169. Patients with poor outcomes had a higher mean (SD) H-score than those without; intubation (96.0 [50.0] vs 75.0 [35.0], p < 0.01), ECMO (113.0 [25.0] vs 93.0 [50.0], p < 0.01) and death (98.0 [62.0] vs 93.0 [48.0], p < 0.01). Factors associated with H-score were diabetes (β coeff = − 10.4, p < 0.01), abdominal pain (β coeff = 19.1, p < 0.01), duration of COVID-19 symptoms (β coeff = − 0.7, p = 0.049), and days before ICU admission (β coeff = − 1.2, p = 0.01). H-score showed a fair ability to discriminate COVID-19 outcomes (AUC 0.61, 95% CI 0.54–0.67). An H-score of 85 was the optimal cut-off with a sensitivity 69% and 1-specificity 53%.

Conclusion: Despite its association with severity in COVID-19, H-score's ability to predict poor outcomes was only fair, indicating differences in the cytokine storm faced in COVID-19 compared with that during secondary HLH.
National clinical guidelines: The diagnosis and management of asthma in adults
Authors: Al Huneiti Rasmeh , Saeed Bushra , Nusr Rasha , Radwan Eman , Al-Katheeri Huda
Published: April 2022

Background: Qatar has culturally diverse health professionals; and therefore, the care provided may vary according to their background, resulting in variations in care. To bridge this gap, the Ministry of Public Health (MOPH) has established the National Clinical Guidelines (NCG) Program, which aims to reduce variation in care delivery, improve value-add from the healthcare system, adopt international best practices to local context, and enable insurers and providers to access the most currently reviewed evidence-based practice in diagnosis and management of diseases.

The NCG for “Diagnosis and Management of Asthma in Adults” was developed in collaboration between Strategic Planning and Performance Department and Subject Matter Experts (SMEs) who are practicing healthcare professionals representing different healthcare organizations in Qatar.

The NCG aims to standardize the management and treatment received by adult patients with asthma across the healthcare system and adapt the best practice recommendations in the management of asthma to the culture, customs, practice, and formulary of Qatar.

Methods: This NCG has been developed through a rigorous process that aligns with international best practices and localized to the context of Qatar, involving:

• Extensive literature search for reputed published evidence specific to NCGs.

• Critical appraisal of the literature.

• Development of a baseline draft guideline.

• Review of the baseline draft by SMEs and patients.

• Review of the guidelines by the National Clinical Guidelines and Pathways Committee (NCGPC) from stakeholder organizations across Qatar.

Results: The first edition of the NCG was published on the MOPH website on December 14, 2016; and it was updated and republished on August 22, 2019. A Patient Information Leaflet (PIL) was prepared from the NCG using simple language for use by the patients. The NCG is currently under an updation process based on new evidence since August 22, 2019. A live demo was developed on how to access the NCG and its relevant pathways from the MOPH website and navigate each section of the guidelines.

Conclusion: These NCGs will improve the quality of care for patients with asthma and advocate for the best clinical practice strategies on the management of asthma in adults.
Non-invasive diagnostic test for cow's milk allergy: A cross-sectional, descriptive study
Authors: Raziani Yosra , Othman Brwa , Ahmad Asuda , Qadir Sozyar
Published: April 2022

Background: Cow's milk allergy is a common type of allergy in infants that is caused by the immune response to proteins in cow's milk. Digestive manifestations, atopic dermatitis, and respiratory discomfort are some of the clinical manifestations that appear; however, none of them are objective criteria to confirm the diagnosis, which may result in misdiagnosis, treatment hindrance, and parental concerns. Therefore, new methodologies for an accurate and immediate diagnosis is essential.

Methods: In this descriptive study, infants referred to the pediatric health center in Sulaymaniah were selected during a period of 1 year. The data were collected using a demographic questionnaire and the Cow's Milk Related Symptom Score (CoMiSS). Chi-squared and independent t tests were used to analyze the data.

Results: The findings of the present study indicated that among 250 infants (117 boys, 133 girls), with a mean ±  SD age of 2.9 ± 1.6 years, 21% were breastfed, 39% were fed both cow's milk and breast milk, and 60% were fed only cow's milk. The contingency of cow's milk allergy was positive in 35% of infants. According to this questionnaire, 18% of the participants got a score of 0–5, 47% scored 6–11, and 35% scored ≥ 12. A significant relationship was found between cow's milk allergy and the participants’ diet (p < 0.001). A significant association was also found between age-dependent growth index (weight p = 0.04, height p = 0.01, and head circumstance p = 0.02) and cow's milk allergy.

Conclusion: Although common problems in infancy such as colic and reflux may interfere with an accurate diagnosis of cow's milk allergy, give false-positive results, and decrease the reliability of CoMiSS; there is a need for non-invasive and easy methods for early diagnosis and improving awareness to encourage parents to take preventive measures.
Foreign body aspiration in an adult: An endobronchial “Melon-oma”
Authors: Ul Haq Irfan , Hameed Mansoor , Ahmed Shakeel , Hussein Mousa
Published: April 2022

Background: Foreign body (FB) aspirations in adults are relatively uncommon. The most commonly aspirated FBs in adults are organic, especially vegetable matter, peanuts, and fragments of bones. We report a rare case of a FB discovered in the left main bronchus of an adult male admitted to the intensive care unit. Case report: A 52-year-old male smoker with COPD presented to the emergency department with a two-day history of increasing dyspnea and cough. He was hypoxic and febrile with a temperature of 38°C. Auscultation revealed decreased breath sounds over the left lung and a few rhonchi on the right side. Chest x-ray showed left lung collapse. His condition rapidly worsened, and he was immediately intubated for acute respiratory failure. CT chest identified a large endobronchial mass obstructing the left main bronchus. Flexible bronchoscopy confirmed a soft and mobile brownish lesion in the left main bronchus. The histological appearance of the specimen retrieved was consistent with an organic foreign body. This was later identified as a melon chunk. It was removed successfully via flexible bronchoscopy by cutting it into smaller pieces to aid retrieval. Conclusion: FB aspiration can occur in all age groups but is less common in adults accounting for only 0.16%–0.33% of adult bronchoscopic procedures. Early detection of an aspirated FB is essential to avoid significant complications, morbidity, and mortality.
Pre-procedural SARS-CoV-2 PCR testing in the pulmonary function laboratory at a tertiary government hospital in Qatar: A clinical audit
Authors: Parveen Fida , Thomas Merlin , Hameed Mansoor , Raza Tasleem , Panneerselvam Balamurugan , Nair Rajalekshmi , Ahmed Mushtaq , Ul Haq Irfan , Al Mohammed Ahmed , Abdul Sattar Hisham
Published: April 2022

Background: Prior to pulmonary function testing (PFT), local and international recommendations advise pre-procedural screening. Pulmonary function tests generate aerosol droplets containing millions of viruses, significantly increasing the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission not only to the individuals in and around the PFT office, but also to subsequent patients who undergo the test later in the same room.

Methods: This clinical audit was carried out to establish the rate of positive pre-procedural SARS-CoV-2 PCR testing before a PFT. The data were obtained over a 6-week period from our ATS accredited pulmonary function laboratory at the Hamad General Hospital, Qatar (December 01, 2021, to January 10, 2022). The PFT laboratory was closed from January 10, 2022, till the date of this report (January 27, 2022) owing to an increase in COVID cases in the community in Qatar during the fourth wave.

Results: All the patients scheduled for PFT were asymptomatic of COVID-19. A total of 331 individuals were scheduled for PFT, and 221 PFTs were performed. There were 109 no-shows for both the PCR and the PFT. Between weeks 1 and 4, all the pre-procedural SARS-CoV-2 PCR tests were negative. The weekly average number of COVID-19 cases in Qatar increased from 157 per 100,000 population in week 1 to 2,918 in week 6.2 There was a similar trend in the pre-procedural SARS-CoV-2 PCR tests that increased and resulted in identifying 9 cases with positive SARS-CoV-2 PCR test over weeks 5 and 6 ().

Conclusion: As the number of documented positive SARS-CoV-2 PCR tests in the community grew, so did the pre-procedural COVID-19 PCR positivity and the number of no-shows. The large number of no-shows may indicate greater worry or concern about contracting COVID-19 when visiting the hospital amid peak community cases. Our findings further call into question the utility of routinely performing pre-procedural PCR screening in asymptomatic cases when the prevalence of COVID-19 is low in the local population. Perhaps, it is time to consider replacing this with on-the-spot quick antigen testing for more effective use of resources.
Selective COX-2 inhibitor continues to be a safe alternative in patients with nonselective NSAIDs hypersensitivity
Authors: Thalappil Sherin , Al-Nesf Maryam
Published: April 2022

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) cause different types of allergic and pseudo allergic reactions. This results in difficulties in clinical practice. Most cases of NSAID hypersensitivity are mediated by the inhibition of cyclooxygenase-1 enzyme (COX-1), which results in depletion of the protective prostaglandin E2, and promotes the unrestrained synthesis of inflammatory mediators from mast cells. Selective COX-2 inhibitors are considered safe alternatives in patients with NSAID allergy, although hypersensitivity reactions to COX-2 inhibitors have also been reported. Our study aimed to report the experience in Qatar for using COX2 inhibitors as an alternative treatment for nonselective NSAID allergy.

Methods: Data of patients who underwent open challenge with a single dose of oral celecoxib 200 mg were retrieved from the procedure log of the Allergy and immunology Division in Hamad medical corporation, Doha, Qatar, from 2013 to 2022. The challenge was considered positive if the patient developed cutaneous or respiratory symptoms.

Results: A total of 31 patients were identified; 4 with a history of celecoxib allergy. The remaining 27 (23 females and 4 males); with mean ( ± SD, range) age of 42 ( ± 12, 20–65) years had hypersensitivity to one (n = 11) or more than one (n = 16) nonselective NSAID, manifested as cutaneous, respiratory, or anaphylactic symptoms. Those 4 patients with celecoxib allergy were challenged and only one with a historical reaction of anaphylaxis developed anaphylaxis during the challenge. Celecoxib was well tolerated in all 27 patients with hypersensitivity reactions to nonselective NSAIDs. Also, patients were contacted by telephone call at 24 hours and after 1 week with no evidence of delayed reactions.

Conclusions: Selective COX-2 and nonselective NSAIDs have similar overall efficacy as analgesic, anti-inflammatory, and antipyretic agents. Hypersensitivity reaction to COX-2 inhibitors has been reported; however, it is rare. So, it is safer to challenge the patients with COX-2 inhibitors before prescribing them as alternative medication in patients with Nonselective NSAID allergies. We plan to conduct a single-/double-blind placebo-controlled study for more patients, especially using graded challenges for high-risk profile candidates. Also, it may be of significance to test more than one type of selective COX-2 to avoid drug-specific reactions.
Contributions of nurse specialists in the allergy and immunology service and patient care
Authors: Ibrahim Yaldez , Bin Naji Slim , Mobayed Hassan , Al-Nesf Maryam
Published: April 2022

Specialist nurses have a crucial role within the allergy and immunology specialty that reflects their competence in an increasingly complex area of work and ability to use advanced diagnostic testing and therapeutic modalities. A specialist nurse in Qatar follows the local Hamad Medical Cooperation (HMC) guidelines and the competency published by the British Society for Allergy and Clinical Immunology (BSACI).

Specialist Allergy Nurses

Learning domain: Learn and review the written standard operating procedure (SOP) and protocols for all diagnostic and therapeutic allergy procedures, including skin prick testing (inhaled, food, and others), intradermal testing, skin patch testing, penicillin testing, food and drug challenges, different desensitization protocols, and biologics and other medication administration. In addition, learn the protocol for immunotherapy administration and maintain an updated knowledge of trends and developments in the field by reading relevant articles, journals, and related material and attending seminars and conferences, as needed.

Maintain a safe work environment: Perform all the above procedures and medication administration with a high grade of competency under physician supervision. Apply quality measures to ensure safety. Furthermore, perform stocktaking by regularly checking procedure requirements, availability of items and consumables, date of expiry of items, and medications. Monitor the patients closely during drug and food allergy challenge procedures and record and report patients’ vitals and reactions to treating physicians. Ensure that a patient stays the required observation time after injection(s).

General care: Assess patient needs and suggest solutions to patient care problems. Provide education and resources for the patient and family support as needed. React appropriately and on time during patient reaction situations to mitigate early adverse reactions. Maintain patient, employee, and clinic confidentiality.

Specialist Immunology Nurses

• Develop specialist knowledge and experience in immunology.

•Develop nurse-led clinics for administering immunoglobulin replacement therapy safely and effectively based on patients’ preferences (IV vs. SC and in-hospital vs. home programs).

•Coordinate communication between members of the multidisciplinary team to facilitate the appropriate delivery of care.

•Provide education and resources for the patient and family support (insurance issues, resources for vaccination recommendations, concerns regarding traveling and vacations, pregnancy, and any other lifecycle changes).
THE EFFECTS OF COVID-19 PANDEMIC ON THE IMPLEMENTATION OF SUSTAINABLE DEVELOPMENT GOALS IN THE MILITARY ORGANIZATION
Authors: HRAB Daniela-Elena
Published: April 2022

This article makes a brief analysis of the sustainable development goals that are applicable in the military organization and identifies, through the literature-review method, the main ways in which the military organization was affected by the COVID-19 pandemic, focusing on the evolution of military spending. The ultimate goal is to establish how the pandemic has influenced the implementation of sustainable development goals in the military organization, in order to provide strategic management with recommendations to increase the resilience and sustainability of the military organization. The main conclusion of this research is that the pandemic did not have a significant impact in the short term, but in the medium and long term the situation may change, which calls for adaptation, cooperation, coordination and caution in the configuration of defence spending. As a secondary conclusion, it can be considered that the pandemic can have an accelerating effect on sustainable development policies, the military organization being called to benefit from the identified lessons and new opportunities, in order to increase the response capacity.
POSSIBILITIES TO EVALUATE THE PERFORMANCE OF REGULARITY/COMPLIANCE AUDIT USING THE BALANCED SCORECARD METHOD (BSC)
Authors: TIMOFTE Vasile
Published: April 2022

The regularity/compliance audit is a specific type of internal audit meant to examine the processes, activities and actions carried out in public or private entities, on the basis of a frame of reference designed in such a way as to allow at the level of these structures an assurance on the effectiveness of risk management, control and governance processes. This activity needs to be continuously refined and modernized in order to be closely connected to the requirements and needs in continuous dynamics of those audited, and the Balanced Scorecard model (BSC) offers such a possibility. In the final part we identified, according to the requirements of this model, a set of questionnaires for auditors and audited, performance indicators, elements of innovation, connection and strategies, which applied or investigated in military entities, will allow highlighting the possibilities to increase the performance of internal audit through regularity / compliance missions.
Apontamentos sobre a EJA: análise do fluxo de vagas e o acesso no RS, interfaces de um período de negação de direitos
Authors: Mesch Ferreira da Silva Giselda , Mariglei Severo Maraschin , Priscila Rostirola Ritzel
Published: April 2022

Este estudo tem como foco principal realizar apontamentos sobre a oferta/redução de vagas na modalidade EJA no RS. Para realização deste estudo, optou-se pela abordagem quali-quantitativa, levando em consideração dados como a oferta escolar para a modalidade EJA no RS, analisando e relacionando dados de oferta das esferas estaduais e municipais dentro do estado do RS, no período compreendido entre 2014 e 2021, quando da homologação das metas estabelecidas no Plano Nacional de Educação que previa importantes diretrizes para a educação de jovens e adultos. Os resultados da análise dos dados mostram que boa parte dos estudantes da EJA enfrentaram uma série de dificuldades ao longo da vida que os fizeram abandonar os estudos. O estudo revelou que a oferta de vagas teve uma redução de 68,3%, entre 2018 a 2021, em escolas estaduais do RS e de 29,32% nas escolas municipais do estado, o que não se apresentou de outra maneira a nível de país que teve uma diminuição de 34% na oferta da modalidade. A pesquisa faz emergir um debate imprescindível de construção de políticas públicas para a modalidade de EJA, pois há um vasto número de estudantes a serem atingidos neste campo educacional.
optimized time series data clustering method for NN network
Authors: Ramesh Goli Raja , Radha D , Reddy Anantula Pranayanath , Kumar Chanda Raj , Kumar Prathipati Ratna
Published: April 2022

Time series data is a common sort of data that can be found in a variety of fields. Clustering time series data has a wide range of uses and has drawn scholars from several fields. A unique approach for shape-based time series clustering is proposed in this research. Using the complex network principle, it may reduce the bulk of data, enhance efficiency, and not reduce the effects. To begin, a one-nearest neighbour network is constructed using time series items that are comparable. The similarity is measured in this step using the triangle distance. Each node in the neighbour network represents a single time series object, whereas each connection indicates a neighbour relationship between nodes. Second, high-degree nodes are selected and used to cluster. Dynamic time warping distance function and hierarchical clustering algorithm are used in the clustering process. Finally, several studies are carried out using both synthetic and actual data. The findings demonstrate that the suggested approach is both efficient and effective.
Effectiveness of magnetic field in stimulation of biochemical and enzymes activities in seedling and callus of Nigella sativa
Authors: AL-Allaf Sawsan J. A. , AL-Baker Rehab A. H.
Published: April 2022

This current study investigated the influence of Magnetic Field from Winding coil magnet about ( 400 mT ) for different exposure periods ( 0, 30 , 60 , 90 , 120 , 150 min ) on seed germination, callus initiation, and callus fresh weight, protein, carbohydrate and proline content and vitality , in addition to the efficacy of some antioxidant enzymes . The results indicated that the highest seed germination percentage was when exposed for an (90 Minutes). Also found that the best exposure period for acceleration of callus initiation was (30 minutes). Fresh weight, protein, proline, carbohydrates content and callus vitality got a better result under (90 minutes) of magnetic field exposure . On the other hand, the antioxidant enzymes activity significantly increased with 150 minutes M.F treatment.
Tissue expansion in oral and maxillofacial surgery
Authors: Gawande Darshana D. , Singh Ankit , Ukey Viplove Trisharan , Madan R. S. , Manjula V , Shrivastava Swatantra
Published: April 2022

Tissue expansion offers s new frontier in head and neck reconstruction by creating an excessive soft tissue, contiguous to the defect, with identical colour, thickness and appendages is a most vital and valuable tool in reconstruction of head and neck which requires meticulous treatment planning, correct patient selection and precise stepwise execution15. Like other modalities present in oral and maxillofacial surgery have some unfavourable results, tissue expansion is also present with some unfavourable complications. However as long as one anticipates these sequelae and complications and is able to tackle them satisfactorily, it remains one of the most exciting advancements in our field in the last 50 years.
Dentigerous cyst associated with complex odontoma
Authors: Singh Ankit , Gawande Darshana Diliprao , Kharsan Vinay , Madan Ramnik Singh , Manjula V , Vyas Shruti
Published: April 2022

The complex odontoma is non aggressive hamartomatous developmental malformations usually asymptomatic, with slow evolution and may be associated with other disorders such as dentigerous cyst as outlined in our case. The treatment of choice is surgical excision of the lesions along with the tooth associated to the cyst. Surgical excision of odontome with cyst in children should be performed with careful, imperative, immediate planning; preventing injury to vital structures and developing occlusion.
Sales Territory Design and Salesforce Performance in the Detergent Manufacturing Companies in Kenya
Authors:   University of Nairobi, Mwangi Benson Muchoki , Kibera Francis N. ,   University of Nairobi, Kinoti Mary ,   University of Nairobi, Obara Magutu P. ,   University of Nairobi
Published: April 2022

In today’s competitive and dynamic markets, one of the most critical challenges businesses face is how to improve the performance of their salesforce. The role of the salesforce has evolved from just implementing the selling function to become a core value creator for both the customers and the sales organizations. This study sought to establish the effect of sales territory design on salesforce performance in the detergent manufacturing companies in Kenya. The study adopted the positivism approach and a descriptive cross sectional design. The population of the study was the salesforce in the detergent producing companies in Kenya who are members of Kenya Association of Manufacturers (KAM) as at December 2018. There are 557 salespeople spread across the 40 detergent manufacturing companies in Kenya. The sample size was 326 respondents. The study utilized primary data which was collected by administering semi-structured questionnaires. The data was analyzed applying a mixture of both descriptive and inferential statistics to describe the manifestations of the variables in the data collected. Simple linear regression analysis was utilized to determine the extent to which the variables are related. The null hypothesis that sales territory design has no significant effect on salesforce performance in detergent manufacturing companies in Kenya was rejected. Thus, sales territory design has significant effect on salesforce performance in detergent manufacturing companies in Kenya. This therefore indicates that sales territory design is critical in determining salesforce performance in detergent manufacturing companies in Kenya. The study recommended that the detergent manufacturing companies and other stakeholders like Kenya Association of Manufactures should focus on the developing of efficient and effective sales territory frameworks that make it easy and cost effective for the salesforce to reach the customers and ultimately deliver more sales and at competitive prices Keywords: Sales Territory Design, Salesforce Performance & Detergent Manufacturing Companies
Strategi Guru Akidah Akhlak dalam Pembentukan Akhlak Siswa di Mts Ma’arif Karangasem Bali
Authors: Mustofa Ali , Ali Firman Ali Firman
Published: April 2022

Akhlak adalah suatu yang sangat penting. Penelitian ini membahas penerapan strategi pembelajaran guru akidah akhlak dalam pembentukan akhlak  siswa di MTs Ma’arif. Tujuan penelitian ini adalah untuk mengetahui strategi guru akidah akhlak, akhlak siswa, dan  faktor pendukung dan penghambat dalam pembentukan akhlak. Untuk mendapatkan jawaban terhadap permasalahan di atas maka penulis melakukan penelitian dengan kualitatif, Setelah melakukan analisis terhadap data yang diperoleh maka hasilnya menunjukkan adanya peningkatan akhlak siswa di MTs Ma’arif, yang meliputi sifat al-amanah (setia, jujur dan dapat dipercaya), al-wafa (menepati janji), tawadhu’ (rendah hati) dan benar/jujur. Semua itu bisa dicapai melalui penerapan strategi pembelajaran dengan berbagai macam strategi pembelajaran yaitu strategi pembelajaran langsung, inkuiri dan kooperatif. Adapun proses penerapan strategi pembelajaran tersebut yang secara umum dilakukan melalui tiga tahap yaitu tahap permulaan (praintruksional), tahap pengajaran (intruksional) dan tahap penilaian tindak lanjut.Implikasi dalam penelitian ini adalah, berbagai proses penerapan strategi pembelajaran guru akidah akhlak dalam pembentukan akhlak siswa di MTs Ma’arif harus tetap diterapkan, dan ditingkatkan dengan berbagai kreativitas yang mampu menunjang proses pembinaan akhlak mulia bagi peserta didik. Selain itu, upaya maksimal yang telah dilakukan guru akidah akhlak dalam pembentukan akhlak mulia peserta didik juga perlu inovasi dengan semakin menggali potensi-potensi sumber daya pendidikan yang ada  guna pembinaan yang berkelanjutan. Dukungan seluruh aspek pendidikan hendaklah sejalan dengan program pembentukan yang dilakukan guru akidah akhlak, turutama keteladanan, pembiasaan dan pengawasan dalam lingkungan keluarga, masyarakat dan sekolah.
Internalisasi Pemahaman Moderasi Multikultural Dalam Pendidikan Islam Masa New Normal
Authors: Uswatun Hasanah Uswatun Hasanah , Ida Faridatul Hasanah Ida Faridatul Hasanah
Published: April 2022

Abstrak: Pendidikan Islam pada masa new normal membutuhkan penyesuaian secara besar-besaran sesuai dengan kebutuhan masyarakat tanpa menghilangi nilai-nilai pendidikan Islam serta nilai kearifan lokal yang menjadi ciri khas pendidikan Islam di Indonesia. Selain itu, karakteristik dari keramahan serta kemoderatan dari kehidupan sosial bermasyarakat harus tetap diinternalisasikan dalam pendidikan Islam sehingga nilai-nilai toleransi harmonisasi dan pluralisme dapat dioptimalkan. Oleh karena itu, Pendidikan di masa pandemi juga harus tetap diarahkan untuk menciptakan suatu sistem pendidikan Islam yang tetap komprehensif namun fleksibel dan demokratis untuk menghadapi berbagai permasalahan kehidupan bermasyarakat serta didukung dengan kemampuan dan keahlian teknologi sehingga dapat memungkinkan untuk mengoptimalisasikan pengembangan potensi peserta didik secara lebih alami dengan tidak keluar dari ajaran dan syariat Islam. Kemampuan sosial serta sikap penerimaan dengan berbagai perbedaan yang ada di masyarakat perlu menjadi titik tekan dan fokus pembelajaran agar sikap beragama yang toleran dapat dimiliki oleh seluruh peserta didik pada lembaga Islam.
Deskripsi Kemandirian Siswa dalam Pembelajaran Daring Pada Masa Pandemi Covid
Authors: Indah Fajrotuz Zahro Indah Fajrotuz Zahro , Rizky Amalia Rizky Amalia , Sugito Sugito
Published: April 2022

Penelitian ini bertujuan untuk mengetahui gambaran kemandirian belajar siswa SMKN Ngraho Bojonegoro dalam pembelajaran daring pada masa pandemi covid-19. Penelitian ini menggunakan metode kuantitatif deskriptif. Populasi dalam penelitian ini adalah siswa SMKN Ngraho Bojonegoro. Teknik sampling yang digunakan adalah proportional stratified random sampling dengan sampel sejumlah 238 siswa berdasarkan tabel Krecjie untuk menentukan ukuran sampel minimum. Instrumen penelitian yang digunakan adalah skala kemandirian yang berupa skala likert sebanyak 30 item pernyataan. Sebelum diberikan kepada sampel penelitian, instrumen diuji validitas dengan menggunakan SPSS rumus Product Moment dan diketahui ke 30 item valid, selanjutnya diuji reliabilitas dengan menggunakan SPSS rumus Alpha Cronbach dan dihasilkan nilai reliabilitas sebesar 0,90. Setelah diuji validitas dan reliabilitas dilakukan penelitian dengan menyebarkan instrumen kepada sampel penelitian. Uji analisis statistik deskriptif menggunakan SPSS versi 22.0, diperoleh skor rerata sebesar 2,89 dengan standar deviasi sebesar 0,278 menunjukkan bahwa tingkat kemandirian belajar siswa dalam pembelajaran daring pada masa covid-19 cenderung rendah. Pada 3 indikator kemandirian belajar diketahui siswa menunjukkan kemandirian yang paling rendah pada kemandirian emosional, dilanjutkan kemandirian nilai lalu kemandirian tingkah laku. Faktor penyebab rendahnya kemandirian adalah kebiasaan belajar dan teknologi yang kurang mendukung.
Penggunaan Media Flash Card untuk Meningkatkan Kemampuan Menghitung Rumus Bangun Ruang Balok di MI Islamiyah Sendang Agung Bojonegoro
Authors: Bakhtiar Moch. Bakhtiar
Published: April 2022

Artikel ini membahas tentang penggunaan media flash card untuk meningkatkan kemampuan menghitung rumus bangun ruang balok kelas V MI Islamiyah Sendang agung dengan rumusan masalah pokok dalam penelitian ini adalah “Apakah penggunaan media flash card ini dapat meningkatkan kemampuan menghitung rumus bangun ruang balok?Tujuan dari penelitian ini adalah untuk mengetahui penggunaan media flash card dapat meningkatkan kemampuan siswa dalam menghitung rumus bangun ruang balok bagi siswa kelas V MI Islamiyah Sendang agung.Penelitian ini menggunakan jenis metode Penelitian Tindakan Kelas (PTK) dengan model Kurt Lewin dengan melakukan dua siklus tindakan, yang pada setiap siklus terdiri dari empat tahap diantaranya perencanaan, pelaksanaan, pengamatan dan refleksi. Pengumpulan data dilakukan dengan cara tes tertulis yang dilakukan setiap akhir siklus.Hasil penelitian menunjukkan adanya peningkatan kemampuan siswa dalam menghitung rumus balok (panjang, lebar tinggi) yang dibuktikan dengan tahap pretest pada kemampuan awal siswa yang dapat mengerjakan soal dan lulus hanya 25%, dan pada siklus I meningkat menjadi 56,25% dan pada siklus II juga mengalami peningkatan menjadi 81,25%. Dan dapat dikategorikan media flash card cocok diterapkan dalam Meningkatan kemampuan siswa dalam menghitung rumus balok (panjang, lebar tinggi)
Periapical Cysts. Surgical and Implantology Contemporary Approach. Case Series
Authors: Cabrera Edgar
Published: April 2022

Currently, our patients come to our consultations with knowledge of oral implantology requesting immediate resolution protocols, having us as clinics to apply more advanced technologies where diagnosis plays a determining role. The appearance of periapical lesions until some time ago meant an inconvenience in the development of these treatment plans, having to delay for 3-6 months the completion of the case. The study, development and benign behavior of this type of search is quite clear in the literature, demonstrating over time the importance of a timely diagnosis and an effective surgical technique for its resolution. There are many consensuses described in the literature on immediate implementation, but it is necessary to make case reports with clinical and radiographic follow-up where the management and application of minimally invasive surgical techniques that allow extraction, cyst enucleation, bone curettage, can be shown. guided bone regeneration and finally immediate implantation, definitively shortening the treatment time and increasing the regenerative potential of our jaws and therefore the satisfaction of our patients.
TRATAMENTO HOMEOPÁTICO EPISÓDICO E MOXABUSTÃO EM UM COELHO COM ÚLCERA DE CÓRNEA– RELATO DE CASO
Authors: LUIZA DE SOUSA BARBOSA MARIA , DE PAULA COELHO CIDELI , ANGÉLICA SALÍCIO BRANDÃO LARISSA
Published: April 2022

O uso da moxabustão e suas diversas modalidades de aplicação tem ganhado força no mundo atual, para tanto este trabalho tem como objetivo relatar a eficácia da terapia de moxabustão em um coelho com ulcera de córnea e o uso efetivo de Arnica Montana 30cH para controle de dor e inflamação. Palavras chaves: Coelhos, Homeopatia; Moxabustão; Ulcera de Córnea