bluuebunny/crossref_metadata_2025 huggingface dataset:
Infected patent urachus in a young male: Primary care perspective
Authors: Ahmad Sabri Siti Asiah , Muhammad Juliawati , Muhamad Rosediani
Published: June 2024

Abdominal pain is a common presenting complaint in a primary care setting. Umbilical discharge secondary to umbilical anomalies is usually diagnosed in children and is rare in adults. This case highlights the possibilities of umbilical anomalies as causes of undifferentiated abdominal pain and umbilical discharge in adults. A 24-year-old male presented with a recurrent history of undifferentiated lower abdominal pain and umbilical discharge but was not diagnosed appropriately, leading to multiple visits to general practitioners and emergency departments for four years. An abdominal ultrasound was done, which revealed a hypoechoic tubular structure at the midline of the abdomen. A diagnosis of patent urachus was made and he was then referred to the surgical team for excision of the patent urachus.
Primera evidencia formal sobre la presencia de Cercosaura parkeri (Ruibal, 1952) (Squamata: Gymnophthalmidae) en el departamento de Cochabamba, Bolivia
Authors: Quinteros-Muñoz Oliver , Carpio Rene
Published: June 2024

Reportamos el primer registro formal de Cercosaura parkeri (Ruibal, 1952) para el departamento de Cochabamba, Bolivia, en base a registros comprobables provenientes de la ecorregión de los Bosques secos Interandinos del departamento. Este registro no sólo corrobora la presencia de esta especie para el departamento, a su vez extiende su registro en más de 90 Km al oeste, desde el registro más cercano en Comarapa, Santa Cruz, Bolivia. Se confirma también el registro más alto para la especie en Bolivia y Sudamérica.
Human Immunodeficiency Viral Reverse Transcriptases: Analyses of the Active Sites of the Polymerase Domain and Drug-Resistant Mutants of the Reverse Transcriptases
Authors: Peramachi Palanivelu
Published: June 2024

It is well-known that human immunodeficiency viruses (HIVs) cause the chronic, potentially life-threatening condition known as human Acquired Immuno-Deficiency Syndrome (AIDS). As the lifecycle of HIVs heavily depends on the crucial enzyme, the reverse transcriptase (RT), it has been used as a potential therapeutic target to treat and control the spread of AIDS. The active site amino acids of the polymerase domain of the RTs and their anti-HIV drug-binding sites are analyzed. The catalytic region of HIV RTs and the E. coli DNA polymerase I showed very similar active site amino acids, suggesting that HIV RTs would have possibly evolved from the bacterial DNA polymerase. The catalytic proton abstractor is identified as a K and the nucleotide selection amino acid as an N. However, the regular template-binding pair –YG- is slightly modified to a –YXG- in HIV RTs. Three completely conserved Ds in HIV RTs are involved in binding to the catalytic Mg2+. The sensitive and resistant strains of HIV-1 for the HIV antiretroviral drug, azidothymidine (AZT), a nucleoside analogue of thymidine, show only a few non-isofunctional amino acid replacements and are located mainly in the palm and thumb subdomains of the RT polymerase, whereas the rest of the polymerase catalytic core and metal-binding sites are completely conserved in AZT-sensitive and -resistant HIV-1 strains. In the drug-resistant mutants of non-nucleoside RT inhibitors of HIV-2, the crucial mutations are located mainly near the -MDD- motif of the catalytic metal-binding region. Even though a large number of amino acid replacements are seen between the RTs of HIV-1 and HIV-2, the polymerase active sites are completely conserved in both. The HIV-1 and HIV-2 catalytic and metal-binding sites are completely conserved in simian immunodeficiency virus (SIV) as well. The absence of DEDD-superfamily of proofreading exonuclease domain in the HIV RTs, might cause the virus to evolve rapidly in patients. A possible mechanism of action for the HIV RTs is also proposed.
Adsorptive removal of zinc icons from aqueous solutions in the presence of Georgia minerals
Authors: D. Ioseliani  , G. Balarjishvili  , N. Kalabegashvili  , N. Nonikashvili  , L. Samkharadze  , I. Javakhishvili
Published: June 2024

The article represents the new chemically active natural minerals of Georgia – travertine and limestone. In this work, for the first time there have been studied adsorptive properties of the mentioned minerals in the process of aqueous solution purification from zinc ions. Materials under study are represented by unprocessed forms of travertine and limestone. Factors having an impact on sorption capacity of these minerals are analyzed based on the experiments. The dependence of degree of adsorption and adsorptive capacity on adsorbent dosage, time contact, adsorbate concentration and solution pH has been studied. Optimum conditions for aqueous solution purification from zinc ions have been selected. Under the mentioned conditions, the maximum efficiency of degree of adsorption and adsorptive capacity has been 89,8% and 29 mg/g for travertine and 82% and 28 mg/g for limestone.
Harnessing big data analytics to revolutionize ESG reporting in clean energy initiatives
Authors: Omowonuola Ireoluwapo Kehinde Olanrewaju  , Gideon Oluseyi Daramola  , Olusile Akinyele Babayeju
Published: June 2024

The integration of Big Data Analytics into Environmental, Social, and Governance (ESG) reporting holds significant potential to revolutionize clean energy initiatives. This paper examines the current challenges in ESG reporting, such as data collection and integration, data quality, regulatory compliance, transparency, and standardization. Big Data Analytics offers advanced techniques, including machine learning, artificial intelligence, predictive analytics, and real-time data processing, which can address these challenges. By leveraging diverse data sources—both structured and unstructured—clean energy projects can achieve more accurate environmental impact assessments, social impact evaluations, and governance analyses. The applications of Big Data Analytics are exemplified through various case studies, such as renewable energy projects, smart grids, and carbon offset programs. The benefits of these applications are vast, including enhanced data accuracy, improved decision-making, increased transparency, better stakeholder engagement, and cost efficiency. However, implementing Big Data Analytics in ESG reporting also presents challenges like data privacy, technological requirements, skills shortage, ethical considerations, and system integration. The future of Big Data Analytics in ESG reporting looks promising with emerging trends like blockchain for data transparency, IoT and sensor technologies, advanced machine learning models, and collaborative platforms. This paper concludes with a call to action for stakeholders to embrace these technologies, highlighting the transformative potential of Big Data Analytics in creating more effective and accountable clean energy initiatives.
PENYULUHAN MAKANAN SEHAT UNTUK BAYI DI DESA PESISIR TAJUNGAN, KECAMATAN KAMAL, KABUPATEN BANGKALAN
Authors: Izzul haq Agung
Published: June 2024

Pada masa petumbuhan bayi ASI merupakan makanan penitng, utama dan terbaik sebab dampat memberikan dampak baik yang terdapat pada zat kekebalan sehingga bisa memeberikan kekebalan untuk melindungi bayi dari berbagai penyakit terutama infeksi dan penyakit lainnya. seiring dengan pertumbuhan bayi maka pertumbuhan gizi diperlukan juga kebutuhan gizi yang cukup pada bayi, oleh dengan sebab ini mulai usia 6 bulan, bayi mulai diberikan makanan pendamping ASI (MP-ASI). Penting sekali memberikan perhatian keapda asupan makanan yang sehat dan bergizi untuk diberikan kepada bayi sehingga dampak buruk dari kurangnya penerimaan gizi bagi bayi bisa dihindari. Pengabdian yang dilakukan di desa Tajungan kecamatan kamal Bangkalan ini dengan Pembinaan yang berkelanjutan juga diperlukan bagi kader sehingga lebih memahami dalam pemberian makanan yang berkualitas bagi keluarga. Kegiatan ini dapat dilakukan secara rutin dan berkesinambungan. Tujuan kegiatan ini adalah memberikan pemahaman kepada ibu tentang gizi balita, tentang pencegahan stunting, sehingga dapat meningkatkan gizi balita melalui praktik pemberian makanan sehingga diharapakn dengan program pengabdian masyarakat ini dapat Mencegah dan mengatasi tejadinya stunting pada balita di Desa Tajungan, Kecamatan Kamal, Kabupaten Bangkalan. Metode  pelaksanaan  dalam  program  pengabdian  kepada  masyarakat  melalui pemberian  penyuluhan  mengenai  stunting  kepada  Ibu-ibu  di  Desa Tajungan, Kecamatan Kamal, Kabupaten Bangkalan. 3 (tiga) tahap yaitu rapat srategi pelaksanaan, survey lokasi  selanjutnya  persiapan  sarana  dan  prasana.  Populasi  dalam  penelitian  ini  adalah ibu-ibu di wilayah Desa Tajungan Kecamatan Kamal Kabupaten Bangkalan
βελτίους, βελτίονες (Moer. β 8)
Authors: Andrea Pellettieri
Published: June 2024

This article provides a philological and linguistic commentary on the comparative forms βελτίους and βελτίονες, discussed in the Atticist lexicon Moer. β 8.
Die leise Macht der Scham
Authors: Ruff Mai-Britt , Petrik Flora
Published: June 2024

Scham lässt sich als Scharnier zwischen individuellen Erfahrungen und gesellschaftlichen Bedingungen begreifen. Im Rahmen unseres Beitrags stellen wir uns die Frage, wie Scham in Machtverhältnissen wirksam wird und fokussieren dabei, in Rückgriff auf Bourdieus herrschaftskritische Soziologie, exemplarisch auf zwei verschiedene, wenn auch miteinander verwobene symbolische Gewaltverhältnisse: Klasse und Rassismus. Wie vermitteln sich Rassismus und Klasse in, durch und mit Scham? Welche Bedeutung kommt Scham in diesen Verhältnissen zu? Und wie lassen sich die Modi dieser Vermittlung systematisieren? Zur Bearbeitung dieser Fragen beziehen wir uns auf zwei interdisziplinäre Forschungsprojekte: Eine qualitativ-empirische Studie zu Bildungsaufsteiger*innen und eine konzeptionell-theoretische Studie über den Umgang mit Scham in der politischen Bildung. Darauf aufbauend rekonstruieren wir drei Facetten von Scham im Kontext symbolischer Gewaltverhältnisse: Scham als Scharnier der (Re-)Produktion (1), Scham als inhärent gekoppelt an Schamabwehr (2) und Scham in der Qualität einer Stimmung (3). Der Beitrag endet mit einem Ausblick auf weiterführende Fragen hinsichtlich der politisch-sozialen Situierung von Scham.
#seggs ohne Scham?
Authors: Pohl Verena , Reuss Tobias , Lahl Aaron
Published: June 2024

Der Artikel widmet sich Umgangsweisen mit Scham im Kontext von Sexualaufklärung auf der Social-Media-Plattform TikTok. Hierfür wird ein Video eines weitreichenstarken Sexualaufklärungskanals zum Thema weibliche Ejakulation/Squirting objektiv-hermeneutisch rekonstruiert. Als Strukturmoment wird die Ambiguität der Selbstdarstellung der Sexualaufklärerin herausgearbeitet, die unauffällig und auffällig, persönlich und unpersönlich, infantil und erwachsen, spielerisch und ernst, professionell und unprofessionell sowie wissenschaftlich und unwissenschaftlich erscheint. Im Umgang mit Sexualscham lässt sich ein spezifisches Verhältnis von Thematisierung und Dethematisierung rekonstruieren. Die Entschämung der weiblichen Ejakulation bzw. des Squirtens wird unter anderem durch Referenz auf statistische Normalität, das Bereitstellen einer wissenschaftlichen Sprache und eine vereinfachte Abgrenzung vom Urin bewirkt. Dabei bleibt die Ejakulation/das Squirten als eher passives Geschehen gerahmt, was die intendierte Aufwertung als Potenz unterläuft. Zudem zeigte sich hinter der manifesten Entlastung das Motiv eines latenten Zwangs zur Schamfreiheit.
Sexualität, Sexpositivität und Scham
Authors: Gärtner Kathrin
Published: June 2024

Scham tritt in sehr unterschiedlichen Situationen auf: wenn Normen und Werte verletzt werden, wenn Menschen gesehen werden, wie sie nicht gesehen werden wollen, aber auch bei Nacktheit und Sexualität. Wenn Sexualität mit strengen Moralvorstellungen belegt ist, überschneiden sich diese Schamfelder. Doch empfinden auch Menschen, die Sexualität grundsätzlich positiv bewerten, Scham in Bezug auf ihre Sexualität, und wenn ja wofür? Um diese Frage zu beantworten, wurden sieben Interviews mit Menschen aus sexpositiven Communities geführt, die mittels Thematischer Analyse nach Braun und Clark ausgewertet wurden. Dabei wurden sieben Themen herausgearbeitet: Bewertung, eigene moralische Maßstäbe, Körperscham, Sichtbarkeit von Sexualität, Ekel, Konstruktion und Dekonstruktion von Scham und Schamüberwindung. Es lässt sich eine Verschiebung von Normen identifizieren, grundsätzlich bleibt der sexuelle Akt, wenn er von unbeteiligten Personen wahrgenommen wird, aber schambehaftet. Es wird diskutiert, inwiefern der potenzielle Ekel der anderen hierbei eine zentrale Rolle spielt und inwiefern der sexuelle Akt selbst eine Möglichkeit zur Überwindung von Ekel und Scham bietet.
Translation techniques of the positive politeness utterances in the Pay It Forward movie
Authors: Widiaswara R. Anantama , Jumanto Jumanto
Published: June 2024

This descriptive qualitative research employed the methods of observation and auto-expert judgment for the data collection and applied Brown & Levinson’s politeness theory (1987) and Molina & Albir’s translation theory (2002) for the data analysis. This research focused on finding the positive politeness strategies and the translation techniques of the utterances obtained from Pay It Forward movie as the data source. Based on the findings of the research, there were 40 utterances with positive politeness strategies as the data under analysis. The research findings, among others, showed that the strategies of Intensify interest to hearer (17.50%) and Exaggerate (17.50%) were dominantly used in the Pay It Forward movie, while the translation strategy of Established equivalent (40.00%) was mostly used in the translation of positive politeness utterances in the movie. It can be concluded here that the translator translates the positive politeness utterances of the source language (English) into the target language (Indonesian) appropriately through the Established equivalent strategy without making any significant changes to maintain the meaning relatively the same in the Indonesian translation subtitles.
Prediction of Precipitation using Multiscale Geographically Weighted Regression
Authors: Taşyürek Murat , Çelik Mete , Kömüşcü Ali Ümran , Dadaser-celik Filiz
Published: June 2024

Prediction of precipitation at locations which lack meteorological measurements is a challenging task in hydrological applications. In this study we aimed to demonstrate potential use of multiscale geographically weighted regression (MGWR) method used to predict precipitation based on relevant meteorological parameters. Geographically weighted regression (GWR) is a regression technique proposed to explore spatial non-stationary relationships. Compared to the linear regression technique, GWR considers the dynamics of local behaviour and, therefore provides an improved representation of spatial variations in relationships. Multiscale geographically weighted regression (MGWR) is a modified version of GWR that examines multiscale processes by providing a scalable and flexible framework. In this study, the MGWR model was used to predict precipitation, which is an essential problem not only in meteorology and climatology, but also in many other disciplines, such as geography and ecology. A meteorological dataset including elevation, precipitation, air temperature, air pressure, relative humidity, and cloud cover data belonging to Türkiye was used, and the performance of the MGWR was assessed in comparison with that of global regression and classical GWR. Experimental evaluations demonstrated that the MGWR model outperformed other approaches in precipitation prediction.
Pengembangan Media Sembung Ukara Berbasis Kearifan Lokal Pada Mata Pelajaran PPKn Kelas IV di SD Negeri 2 Karanggintung
Authors: Fauziyah Mafida Syifa' , Muslim Aji Heru
Published: June 2024

Instructional media is expected to serve as a means to preserve the culture present in society, as education incorporating local wisdom in schools plays a significant role in providing positive experiences for students. It aims to instill great aspirations such as ensuring safety and addressing various social dynamics in the future, one of which is achieved by developing and utilizing instructional media based on local wisdom. This study aims to develop and determine the feasibility of the Sembung Ukara instructional media based on local wisdom. The research employs the RD method with the ADDIE model. Data collection techniques include interviews, observations, questionnaires, and documentation. The results of data analysis are reflected in the product validation outcomes by media and subject matter experts. The media expert validation yielded a score with a percentage of 70%, while the subject matter expert validation scored 91.43%. Both scores fall into the valid category, indicating that the Sembung Ukara media can be used in the instructional process. The research results, based on responses from teachers and students, show that the scores obtained fall into the highly attractive category, with 100% from teacher responses and 97% from student responses. Thus, it can be concluded that the Sembung Ukara instructional media received positive feedback from both teachers and students.
Analisis Metode Mengajar Guru Dalam Meningkatkan Minat Belajar Siswa
Authors: Martiani Situmeang Diana , Manik Anggita Manda , Manik Ganti Meriah , Rohani Siahaan Agnes Dewi , Saragi Freddi , E. A Manik Riswan
Published: June 2024

This research was conducted to determine the learning methods used by teachers to increase interest in learning. This study uses a qualitative method. The findings of this research are the learning methods used by teachers to increase students' varied interest in learning. Variations in methods include lecture, discussion, question and answer, assignment, demonstration, example, advice, reward and punishment, and learning outside the classroom. It is hoped that this varied learning method can increase students' interest in learning.
Kebijakan Trans Metro Deli sebagai Upaya Meningkatkan Layanan Transportasi Umum di Kota Medan
Authors: Khoiria Siti
Published: June 2024

The Trans Metro Deli policy in Medan City is an effort to improve public transportation services. First, this policy provides an integrated and efficient mass transportation system through a special bus network with routes that cross strategic points in the city of Medan. Second, the adoption of information technology in the operational management of Trans Metro Deli allows users to obtain the latest information regarding bus schedules, routes and conditions in real-time, increasing reliability and user comfort. Apart from that, implementing affordable fares is also an important point in this policy, expanding transportation accessibility for people from various economic layers. Third, the Trans Metro Deli policy also prioritizes safety and security aspects in the use of public transportation by establishing operational standards and strict supervision of the bus fleet and personnel. This has a positive impact on public perception and trust in the service. Furthermore, efforts to improve infrastructure including the development of special bus stops and lanes are also an important part of this policy, ensuring accessibility and efficiency in daily operations. In conclusion, the Trans Metro Deli policy in Medan City is a significant step in improving public transportation services by integrating various aspects such as operational efficiency, use of technology, safety, comfort and accessibility. In this way, it is hoped that it can have a broad positive impact on the mobility and quality of life of city residents.
Wajah Budaya dalam Tafsir Nusantara (Studi Analisis pada Tafsir Pase)
Authors: Maula Minnatul
Published: June 2024

Thesymbols of Islam in Aceh are very well preserved as seen in the daily life of the Acehnese people. The maintenance of religious symbols is said to be good and within certain limits believed to be a form of religious practice. This research is expected to achieve the goal of revealing the characteristics and cultural elements in Tafsir Pase, as well as analyzing the contextualization of the interpretation of Tafsir Pase with phenomena that are happening in society. This research was conducted using a qualitative research model, which is research that is general and does not have a certain pattern. The characteristics of Tafsir Pase include the struggle between Islam and local culture in Aceh which is carried out through the translation of the Qur'an into regional languages. Contextualization of the interpretation of Tafsir Pase is seen in various socio-cultural phenomena in Aceh, for example in the meurukon tradition and the peulheuh kaoy tradition. In addition, contextualization is also seen in inter-religious interactions in Aceh.
Analisis Kinerja Pegawai Dalam Memberikan Pelayanan Administrasi Kepada Masyarakat Di Desa Semangat Dalam Handil Bakti Kabupaten Barito Kuala
Authors: Hernany Devia Hetty , Setiawati Budi , Humaidi M. Agus , Puspita Amelia
Published: June 2024

Performance can be known and measured if an individual or group of employees or employees have criteria or benchmark success standards set by the organization. Performance can also be said to be the product of doing something related to a job, position or role in an organization with a maximum sense of responsibility, dedication and loyalty. The performance referred to in this research is all the power and efforts made by employees in providing administrative services to the community. This expected performance is reflected in three aspects, namely, (a) the cognitive aspect, namely the employee's understanding of the administrative service system to the community,(b) the effective aspect, namely the performance of employees in service, is the efforts made by employees to accept and create harmonious interpersonal relationships with the community, (c) the performance aspect is everything that employees do in using their physical bodies in acting so that they can provide good service. best for society
Analisis Perbedaan Pendistribusian Laba Bersih dalam Akuntansi Konvensional dan Akuntansi Syariah pada Sektor Perbankan Tahun 2019
Authors: Qonita Nabila , Syaipudin Usep , Widiyanti Ade
Published: June 2024

This study aims to determine differences in the distribution of profits between conventional accounting and Islamic accounting at the banks listed on the Indonesian Stock Exchange (IDX). This study uses a qualitative descriptive analysis method in which company data used are financial statements and an explanation of the desired data in this study is the 2019 financial statements.The result showed that BCA that using convensional accounting distributed their profits to stakeholders who participate in its acquistion. Meanwhile, profit distribution of BRISyariah that using Syariah Accounting also distributes their profits to stakeholders. The difference in profit distribution between conventional accounting and syariah accounting lies in how profits are shared with customers. In conventional accounting, banks distribute profits through interest, and banks using syariah accounting distribute profits through a profit-sharing system. Additionally, one key difference is in zakat distribution; only banks using Islamic accounting allocate a portion of their profits for zakat.
Implementasi Metode Pembelajaran Berbasis Proyek dalam Pendidikan Tinggi untuk Memfasilitasi Pemecahan Masalah Multidisiplin
Authors: Kamaruddin Ilham , Sari Mike Nurmalia , Papia Jedithjah Naapia Tamedi , M.Usman Patima , Andriani Nining , Kesek Meike Negawati
Published: June 2024

Project-Based Learning (PBL) has emerged as a prominent approach in higher education to facilitate multidisciplinary problem-solving skills among students. This article explores the implementation of PBL in higher education settings and its effectiveness in fostering collaborative learning and interdisciplinary problem-solving abilities. It discusses the challenges faced in implementing PBL, such as paradigm shifts in teaching roles, logistical issues, and disparities in student readiness and motivation. Effective strategies to address these challenges, including faculty training, resource allocation, and student support, are also discussed. The discussion underscores the potential of PBL to enhance student learning experiences and prepare them for the complexities of the modern workforce.
Imajinasi Anak Saat Bermain dalam Lukisan Kontemporer
Authors: Supriyanto Alyssa Khoirunnisa , Sami Yasrul
Published: June 2024

The purpose of this final work is to visualize the form of child imagination when they are playing into contemporary art. In its creation, this artwork visualize the ambiance and what the child imagine when they are playing with their toys or simple things around them. The method in this artwork creation consist of five stages : (1) Preparation, (2) Elaboration, (3) Synthesis, (4) Concept Realization, and (5) Finishing. There are ten artworks that have gone through the art creation process are “Hewan-Hewan di Langit”, “Pesta Teh dan Kue”, “Istana Selimut”, “Sang Penyelamat”, “Seniman Kecil”, “Bertarung”, “Menghindari Lava”, “Belayar Kapalku”, “Aku Melayang”, and “Koki Cilik”.
Pemanfaatan Media Pop Up Book Materi Cara Menghargai Keragaman Suku Bangsa Budaya di Indonesia untuk Meningkatkan Hasil Belajar Pendidikan Pancasila Kelas 4 SDN Rejosari 01 Semarang
Authors: Inayati Inayati , Fajriyah Khusnul , Budiastuti Mintyas
Published: June 2024

Researchers discovered the problem of low student learning outcomes in material on how to appreciate ethnic and cultural diversity in Indonesia in class 1VB at SD Negeri Rejosari 01 Semarang. The aim of this research is to improve learning outcomes on material on how to appreciate national and cultural diversity through the use of Pop Up Book learning media. Kemmis & Mc Taggart's Classroom Action Research will be used. A total of 26 class IVB students at SD Negeri Rejosari 01 Semarang will be the researcher's observation class. Observation and test assessment sheets are used by researchers in data collection. The minimum class completion size is 75. The results of the research show that there is an increase in better learning outcomes when using Pop Up Book learning media. This is reflected in the average for cycle I of 73% and the proportion increased in cycle II to reach 88%. From the data obtained, it is understood that the learning outcomes of class IV students at SDN Rejosari 01 Semarang will be more focused on learning using Pop Up Book media on material on how to appreciate ethnic and cultural diversity in Indonesia, the subject of Pancasila Education.
Investigation of Metaverse Knowledge Attitude and Awareness Levels of Students Studying in the Faculty of Health Sciences of a University According to Variables
Authors: Avcı Işık Sevcan , Karçığa İrem Nur
Published: June 2024

Purpose: This study was conducted as a descriptive study to investigation of metaverse knowledge, attitude and awareness levels of health sciences students according to variables.
Methods: The research was completed with a total of 334 students who agreed to participate in the research between April and May 2023 at the Faculty of Health Sciences of a University in a metropolitan city in Turkey. Introductory Characteristics Form and Metaverse Scale were used for data collection.
Results: Metaverse total score average of the students was 48.5±12.45, and the mean scores of sub-dimensions were respectively; Technology Dimension is 22.8±6.04, Digitization Dimension is 8.8±3.48, Life Dimension is 10.3±3.27, Social Dimension is 6.6±2.34. It was found that Metaverse knowledge, attitude and awareness levels of the students who were married, living in a dormitory, having a high income level, studying in the 4th grade, studying in the department of nursing and audiology, having heard the concept of metaverse before, experienced virtual reality, and defined their internet usage skills as high (p
Intelligent Digital Agents in the Era of Large Language Models
Authors: Faught Benjamin , Lu Helen , Marshall Thomas , Sikka Harshvardhan , Guruprasad Pranav , Gauri Bhavul
Published: June 2024

In recent years, the emergence of large language models (LLMs) has revolutionized the field of artificial intelligence, showcasing remarkable proficiency in natural language understanding and generation. This advancement has spurred a growing research area focused on the development of LLM-based autonomous agents, aiming to achieve human-like decision-making capabilities. This Position Paper provides an overview of current research areas and breakthroughs in LLM-based AI agents. We highlight key advancements and discuss limitations within each area. Furthermore, we identify opportunities for future research to accelerate progress towards realizing more capable versions of AI agents.
Chief of Staff in Performing Arts. Addressing the Absence
Authors: Salvaggio Salvino A.
Published: June 2024

This brief article explores the absence of the Chief of Staff (CoS) role in performing arts organisations and reviews the key scientific literature on the role and functions of a CoS. It examines the potential benefits of introducing a CoS, such as improved operational efficiency, better alignment between artistic and administrative functions, and enhanced communication. The paper discusses the role definition of a CoS and outlines the challenges and limitations of implementing this position in a cultural setting, including resistance from staff, budget constraints, cultural differences, and the complexity of measuring impact. Ultimately, it argues that a CoS could significantly enhance the strategic and operational effectiveness of performing arts organisations.
Effects of Digital Cognitive-Behavioral Therapy for Insomnia in a Tailored Program for Older Adults: Randomized Controlled Trial with One-year Follow-Up
Authors: Ritterband Lee Michael , Shaffer Kelly M , Thorndike Frances , Chow Philip , Gonder-Frederick Linda , Ingersoll Karen , Cohn Wendy , Frederick Christina , MacDonnell Kirsten , Glazer Jillian , Mattos Meghan K , Quigg Mark , Bashir Mudhasir , Morin Charles
Published: June 2024

Background: Older adults with insomnia face considerable challenges accessing treatment given limited availability to first-line therapy (cognitive-behavioral therapy for insomnia, CBT-I) and risks related to second-line treatment (pharmacotherapy).Objectives: Evaluate the efficacy of Sleep Healthy Using the Internet for Older Adults Suffering with Insomnia and Sleeplessness (SHUTi OASIS), a tailored CBT-I program for older adults with insomnia delivered via the Internet. Design: Randomized controlled trial with three conditions (SHUTi OASIS, SHUTi OASIS + stepped support, online patient education [PE]).Setting: Remotely conducted trial in the United States.Participants: Older adults with chronic insomnia (age range 55 to 95).Methods: 311 participants were enrolled and completed assessments of self-reported questionnaires, including the Insomnia Severity Index, and 10 prospectively-collected online sleep diaries at baseline, post (after 9-week intervention period), 6-month post, and 12-month post.Results: Participants randomized to receive SHUTi OASIS (n=207; conditions collapsed given limited need of stepped support) were compared to those receiving PE (n=104). SHUTi OASIS significantly outperformed PE with overall group by time interactions for the primary outcome of insomnia severity (F3,779=30.61, p<.001), as well as for sleep onset latency (F3,774=6.15, p<.001) and wake after sleep onset (F3,778=11.13, p<.001), with participants receiving SHUTi OASIS showing greater improvements at post, 6-months post, and 12-months post. Clinically meaningful indices of insomnia response and remission were also higher among SHUTi OASIS participants compared to PE participants. Conclusion: Older adults can meaningfully benefit from online CBT-I, which holds significant promise to increase access to effective insomnia treatment among this underserved population.
Fracture Conductivity Prediction Based on Machine Learning in Shale – Part I
Authors: Meyer Ella
Published: June 2024

Hydraulic fracturing extracts oil and gas from deep underground, with fracture conductivity being crucial for efficient production. Traditional lab techniques for measuring conductivity are costly and time-consuming. This paper explores using machine learning, specifically multivariate regression, to predict fracture conductivity based on experimental data like Poisson’s ratio and proppant size. Optimizing these models can enhance hydraulic fracturing efficiency in shale formations.
Immunotherapy in Type 1 Diabetes
Authors: Keikhanejad Mohammad Amin
Published: June 2024

AbstractBackground:Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of pancreatic β-cells, leading to insulin deficiency. Standard insulin therapy, while essential, does not cure the disease. Immunotherapy represents a promising approach to modify the disease process.Objective:To review and evaluate various immunotherapeutic strategies for T1D, examining their potential to preserve β-cell function and alter the disease course.Methods:This paper reviews the current literature and clinical trials on immunotherapeutic approaches, including TNFα inhibitors, IL-1 targeting therapies, B-cell therapies, regulatory T-cell interventions, and islet cell transplants. The efficacy, safety, and long-term potential of these therapies are discussed.Results:Primary studies and clinical trials indicate that immunotherapies can modify the disease course, particularly in early-stage T1D. Personalized treatment plans, optimal timing for intervention, and combination therapies targeting multiple pathways show promise in enhancing therapeutic outcomes.Conclusion:Immunotherapy for T1D offers new hope for managing this disease by altering the immune response and preserving β-cell function. Ongoing research into personalized strategies and combination therapies is crucial for achieving better outcomes and improving the T1D patients’ quality of life.Limitations:Key limitations include variable efficacy among individuals, risk of adverse effects, cost, accessibility, and the need for long-term efficacy data. Solutions involve personalized treatment approaches, development of safer therapies, cost optimization, inclusive research, and continuous patient monitoring.
Interdisciplinary industrial design strategies for human-automation interaction: Industry experts’ perspectives
Authors: Mbelekani Naomi Y.
Published: June 2024

Highly automated vehicles are the next generational stage in a long evolutionary process of transport technology. Thus, it is important to consider human factors and ergonomic (HFE) issues that challenge the success of this coming wave of automation technology. Hence, careful consideration of industries’ design differences and similarities for real-world use cases is important. Additionally, a better understanding of the technological, infrastructural, social, and legal aspects that govern human-automation interaction needs to be examined on a comprehensive level, irrespective of industry. In retrospection, an industry-centred approach will help us uncover nuances of understanding on human aspects of advanced manufacturing. Thus, N=20 industry experts were invited to contribute their knowledge. The lessons learned based on different industry experts’ levels of understanding are crucial to consider, mainly for principles or strategies that are aligned with safe and risk-free interaction longevity. Marie Skłodowska-Curie Actions; Innovative Training Network (ITN); SHAPE-IT; Grant number 860410
Happiness, Meaning, and Psychological Richness: People Have Time-Inconsistent Preferences for the Good Life
Authors: Martuza Jareef , Dahlen Micael , Thorbjørnsen Helge , Sjåstad Hallgeir
Published: June 2024

What version of the good life do people want the most, and when do they want it? This paper investigates the relative preference for happiness, meaning, and psychological richness across time. We predicted that people want a happy life consistently high, but express a lower preference for meaning and psychological richness in their ideal present than in their ideal future and past – reflecting time-inconsistent preferences for the good life. This hypothesis was supported in three experiments (N=2,289; USA). Compared to the present, people preferred more meaning and psychological richness when thinking ahead about the rest of their life, and when imagining looking back from the future to the present. Moreover, self-generated preferred activities in the ideal present were less meaningful and psychologically rich than preferred activities in the ideal future and past. The time-inconsistent preference for meaning and psychological richness was moderated by trait self-control, and mediated by perceived effort.
The Three Circles: Testing a New Digital Scale for Measuring the Tripartite Model of Affect Regulation
Authors: Kirby James N. , Moloney-Gibb Dylan , Sherwell Chase Samuel , Day Jamin , Lynn Sasha
Published: June 2024

The tripartite model of emotion regulation (Three Circle Model) comprising threat, drive, and soothing systems underpins Compassion Focused Therapy (CFT). Despite its importance to CFT, activity of each system is typically gauged using proxy self-report measures of emotion, lacking direct measurement of system interactivity. In this study, we developed and psychometrically tested a novel digital measure of the Three Circle model with 311 young adults (aged 18-24, M = 19.6; 223 female, 85 male, 3 non-binary). Evaluation indicated the measure had good construct and concurrent validity with other validated self-report measures of emotion, emotion regulation and mental health. Test-retest reliability of the scale was then established in a second sample with 90 participants (aged 18-24, M = 23.2; 43 female, 46 male, 1 non-binary). These findings support the use of this measure as a brief, dynamic scale that captures central CFT theory and can be easily used with clients or in research contexts.
Prevalence of transparent research practices in psychology: A cross-sectional study of empirical articles published in 2022
Authors: Hardwicke Tom Elis , Thibault Robert T. , Clarke Beth , Moodie Nicholas , Crüwell Sophia , Schiavone Sarah R. , Handcock Sarah , Nghiem Khanh An , Mody Fallon , Eerola Tuomas , Vazire Simine
Published: June 2024

Over a decade of advocacy and policy reforms have attempted to increase the uptake of transparent research practices in the field of psychology; however, their collective impact is unclear. We estimated the prevalence of transparent research practices in (a) all psychology journals (i.e., field-wide); and (b) prominent psychology journals, by manually examining two random samples of 200 empirical articles (N = 400) published in 2022. Most articles had an open access version (field-wide: 74%, 95% confidence intervals [67%-79%]; prominent: 71% [64%-77%]) and included a funding statement (field-wide: 76% [70%-82%]; prominent: 76% [70%-82%]); or conflict of interest statement (field-wide: 76% [70%-82%]; prominent: 73% [67%-79%]). Relatively few articles had a preregistration (field-wide: 7% [2.5%-12%]; prominent: 14% [8.5%-19%]); materials (field-wide: 16% [9%-24%]; prominent: 19% [12%-27%]); raw/primary data (field-wide: 14% [7%-21%]; prominent: 16% [9.5%-24%]); or analysis scripts (field-wide: 8.5% [4.5%-13%]; prominent: 14% [9.5%-19%]) that were immediately accessible without contacting authors or third parties. In conjunction with prior research (Hardwicke et al., 2022), our results suggest transparency increased moderately from 2017 to 2022. Overall, despite considerable infrastructure improvements, bottom-up advocacy, and top-down policy initiatives, research transparency continues to be widely neglected in psychology.
Search in Service of Choice
Authors: Krefeld-Schwalb Antonia , Martinovici Ana , Orquin Jacob Lund , Aribarg Anocha , Bhatia Sudeep , Erdem Tulin , Johnson Eric J. , Reeck Crystal , Schley Dan , Smith Stephanie M. , Speekenbrink Maarten , Stewart Neil , Weber Elke U. , Yang Cathy Liu
Published: June 2024

Understanding consumer search behavior is crucial for businesses and policymakers aiming to effectively engage with consumers through product offerings and interventions. Consumer search remains a significant research topic across disciplines such as marketing, economics, and psychology. However, differences in theoretical assumptions and methodological approaches across these fields pose challenges that hinder interdisciplinary knowledge and theory integration. Theoretical assumptions about search range from randomness in relation to choice value to search being influenced by cognitive and visual factors. Methodological approaches vary from direct observations, like eye tracking, to inferences from observed choices. To address the lack of consensus and facilitate scientific progress, we propose a framework for integrating theoretical and methodological approaches across disciplines. We review six prominent theoretical models, each with distinct terminologies and focus areas. For each model, we review its background, aims, core assumptions, and provide illustrative examples. Our contribution is a synthesis initiative that resolves terminological differences and outlines a path toward theory integration. We discuss how our framework can guide future research and foster a more comprehensive understanding of consumer search and choice.
Inseparability Test on Wheat Production in Nepal: A Case Study of the Saptari District
Authors: Sutihar D.N.
Published: June 2024

Not Available.
Fragmentation in the Landholding Size in Chitwan: An Analysis of the Land Records from 1964 to 1983
Authors: Bhandari Bishnu
Published: June 2024

Not Available.
The Relationship of Plasma Glucose Level and HbA1c among Diabetic Patients attending Chitwan Medical College
Authors: Rimal Brihaspati , Mandal Fuleshwar , Kafle Deepak , Ranabhat Pashupati
Published: June 2024

INTRODUCTION: Type 2 diabetes mellitus is a complex heterogeneous group of metabolic conditions characterized by an increased level of blood glucose, due to impairment in insulin action and/or insulin secretion. Normally the level of HbA1c is less than 6%. HbA1c level reveals the mean glucose level over the previous 10-12 weeks. HbA1c has become a very important part of the management of patients with diabetes mellitus. In addition, the HbA1c is a better indicator of chronic glycemic levels and has a better index to determine the risk for long-term complications as well. So for the screening or diagnosing DM by using glycated hemoglobin (HbA1c) level is very important. The aim of the study was to correlate the plasma glucose level and HbA1c in diabetic patients attending in Chitwan Medical College and Teaching Hospital.
MATERIALS AND METHODS: The study was a cross sectional study carried out in Department of Biochemistry in collaboration with Department of Medicine, Chitwan Medical College, Nepal. The standard screening procedures such as fasting blood sugar (FBS), post prandial blood sugar (PPBS) and HbA1c were the parameters taken into account for the research work.
RESULTS: It was found that both FBS and PPBG strongly correlated significantly with HbA1c values (r = 0.79, p <0.001 and r = 0.75, p <0.001).
CONCLUSIONS: The results suggest that both fasting and postprandial blood glucose significantly correlated with HbA1c. However, our data suggest that HbA1c values may be a weak parameter to identify pre-diabetes cases. HbA1c threshold of ≥ 6.8% can be considered a relatively sensitive marker for the diagnosis of diabetes in the study population.
Predicting Length of Hospital Stay Following Adult Cardiac Surgery: A Prospective Observational Study
Authors: Bashyal Krishnaprasad , Baral Ravi Kumar , Khakural Prabhat , Kadel Prashiddha B. , Gurung Arjun , Bhattarai Anil
Published: June 2024

INTRODUCTION: Despite life-saving benefits, adult cardiac surgery presents challenges due to potential for extended hospital stays and resource strain. Accurately predicting length of stay (LOS) is crucial for efficient resource allocation and patient discharge planning. The study aims to assess factors associated with LOS following adult cardiac surgery and proposed a model for predicting LOS after adult cardiac surgery.
MATERIALS AND METHODS: A prospective observational study was conducted at Manmohan Cardiothoracic Vascular and Transplant Center from September 2019 to May 2021, enrolling 249 adults undergoing cardiac surgery. A prospective observational study was conducted at Manmohan Cardiothoracic Vascular and Transplant Center from September 2019 to May 2021, enrolling 249 adults undergoing cardiac surgery. Non-probability consecutive sampling was employed and a standardized data collection form was used to record patient-related, cardiacrelated, operation-related, and postoperative characteristics including LOS. Descriptive statistics and multivariate analysis were employed to meet the objectives.
RESULTS: The study reported a median length of hospital stay as 10 days with interquartile range 6 days. Patients who experienced prolonged LOS (>13 days) after cardiac surgery accounted for 21.70% of the total sample. In an adjusted relationships, only female sex (AOR= 1.957; 95% CI: 1.022 - 3.745), previous cardiac surgery (AOR: 2.684, 95% CI: 1.314 - 7.885), active IE (AOR: 23.187, 95% CI: 2.467 - 217.969), and ECA (AOR: 3.891, 95% CI: 1.135 - 13.332) were identified as significant predictors of prolonged postoperative LOS.
CONCLUSIONS: By understanding the factors influencing LOS following cardiac surgery, clinicians can optimize care plans and resource allocation, ultimately improving patient outcomes.
Pharmacoeconomic evaluation of Levothyroxine in the treatment of Hypothyroidism in Nepal
Authors: Chaurasia Lokeshwar , Sinha Ragni , Shah Ram Chandra , Deo Sushma , Shah Rajesh
Published: June 2024

INTRODUCTION: Hypothyroidism, is an endocrine disorder, wherein the thyroid gland does not make enough thyroid hormones to meet the body’s needs. Levothyroxine is the mainstay of hormone replacement therapy for hypothyroidism. This study was aimed to evaluate the cost ratio and percentage cost variation, of different brands of levothyroxine, available in the Nepali market.
MATERIALS AND METHODS: This observational pharmacoeconomic study was carried out at Department of Pharmacology of Janaki Medical College, Janakpurdham, Nepal from 5 April to 30 May, 2023. Maximum retail price (Cost) in Nepalese currency (NRs), of various brands of levothyroxine available in Nepali market, of same dosage form, strength and number was reviewed for calculating the cost ratio and the percentage cost variation of levothyroxine manufactured by Nepali and Indian Pharmaceutical companies.
RESULTS: For 120 tablets of levothyroxine, maximum cost ratio of 1.37 and percentage cost variation of 37.14% was observed with 50 mcg of levothyroxine. For 100 tablets of levothyroxine, maximum cost ratio of 1.65 and percentage cost variation of 65.44% was observed with 50 mcg of levothyroxine.
CONCLUSIONS: The findings of this study can be used by a treating physician for prescribing an alternative cheaper brand of levothyroxine for better compliance and for reducing the total health-care cost. Continuous pharmacoeconomic analysis, if carried out at government level, can greatly minimize the cost variation as well as reduce the overall treatment cost for hypothyroid patients in Nepal.