bluuebunny/crossref_metadata_2025 huggingface dataset:
Predicting Mortality Rate in ICU-Admitted COVID-19 Patients Implementing Visual Semi-Quantitative CT Severity Scoring System
Authors: Azadbakht Javid , Lajevardi Zahra Sadat , Abdoli Amir Hossein
Published: October 2022

Abstract: Objectives: The aim of this study was to identify the clinical and laboratory features and CT scan (CT intensity score and pleural effusion) associated with COVID-19 pneumonia to evaluate the relationship between CT scan findings and mortality by comparing deceased patients with normal patients. Methods: In this retrospective case-control study, 290 ICU admitted patients with RT-PCR confirmed COVID-19 pneumonia were investigated. Totally, 150 deceased patients (with confirmed COVID-19 related death) were extracted from the COVID-19 registry of the affiliated university hospital belonging to mentioned period of time (in-hospital mortality subgroup, case), and 150 patients who survived the admission course were randomly selected from the same data set (surviving subgroup, control). Available electronic records for each patient were enlisted, including laboratory and clinical information, and their on-admission computed tomography (CT) images were reviewed. Mortality-related risk factors were compared between case and control subgroups. Results: The mean age of deceased patients (68.20±16.07) was significantly higher than that of the surviving patients (54.72± 19.50) (p <0.001). Diabetes, hypertension, and chronic kidney disease (CKD) were significantly related with higher mortality rates (62.2%, 58.7%, and 80.4% mortality in diabetic, hypertensive, and CKD patients versus 41.7%, 42.1%, and 35.9% in non-diabetics, normotensives, and patients without CKD). Additionally, the mean on-admission air-room SPO2 level in deceased patients (90%) was significantly lower than that of the survivors (93%) (p = 0.001). Lymphocyte count, neutrophil to lymphocyte ratio (NLR), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), lactate dehydrogenase (LDH), fasting blood sugar (BS), blood urea nitrogen (BUN), and Creatinine (Cr), mean CT severity score (CT-ss), and O2 supportive therapy requirement were significantly higher in the mortality subgroup (p <0.05). Pleural effusion showed no significant correlation with short-term mortality. CT-ss of >11, in isolation or in combination with above-mentioned prognosticators, was 64% or 81.4% sensitive, and 60% or of 78.6% specific, to predict mortality. Conclusions: Factors such as advanced age, underlying diseases such as diabetes, hypertension, and CKD, decreased air-room SPO2, and increased lymphocyte count, higher NLR, ESR, CRP, LDH, BS, BUN, and Cr level, as well as higher CT-ss and O2 supportive therapy, are all significantly correlated with higher mortality in ICU-admitted COVID-19 patients.
Chest CT Severity Score, CURB-65 Score, and Their Relationship with In-Hospital- Mortality in COVID-19 Patients
Authors: Azadbakht Javid , Lajevardi Zahra Sadat
Published: October 2022

Abstract: Objective: With every new strain of the SARS-CoV-2 spreading on a fast pace across the borders, an easy-to-calculate and reliable scoring system seems invaluable to identify high-risk patients. This study aims to investigate the relationship between CT severity score (CTSS) and CURB-65 score with mortality in COVID-19 patients. Methods: This study was conducted on RT-PCR confirmed COVID-19 patients admitted to a tertiary teaching center during fifth national wave of disease in one of the early disease epicenters in the country. All enrolled patients underwent chest CT scan within first day of admission. CTSS and CURB-65 scores were calculated and assigned to patients, while radiologist was blinded to clinical and laboratory findings, and they were evaluated for their correlation with in-hospital mortality, additively and separately. Results: Total number of 216 patients (140 males) with a mean age of 56.02 ± 17.34 years (ranging from 4 to 95) were enrolled. We found no significant relationship between CURB-65 score and CTSS (correlation coefficient: 0.065; P: 0.338). CURB-65 scores above 1 was predictive of in-hospital mortality with sensitivity of 56.4% and specificity of 81.9% (P: 0), those for CTSS above 11 were 79.5% and 4 51.5%, respectively (P: 0.001). CURB-65 score >1 and CTSS >11 predicted in-hospital mortality with sensitivity and specificity of 61.5% and 79.7% (P: 0.000). CURB-65 score and CTSS had a higher sensitivity and specificity to predict mortality comparing to each of those separately, but these enhanced statistics were not significant. Conclusion: CURB-65 score is meaningfully stronger than CTSS to prognosticate in-hospital mortality in patients with COVID-19, and it is not significantly correlated with CTSS.
Mechanism and Ways of Transmission and Source of Appearance of Coronavirus Strains
Authors: Bryndin Evgeny
Published: October 2022

Abstract: The mechanism of transmission of infection is a way of moving an infectious agent from an infected organism to a susceptible one. Each infectious disease has its own characteristic pathway of pathogen transmission, which was formed during evolution to preserve the pathogen as a species. The mechanism of pathogen transmission includes three phases: excretion of the pathogen from the host organism into the environment, presence of the pathogen in the environment, introduction of the pathogen into a new susceptible organism. The main mechanism for transmitting coronavirus infection is air-droplet (or air-dust), in which the pathogens are localized in the mucous membrane of the respiratory tract and transferred to the new body through the air. In this transmission path, the pathogen enters the external environment during sneezing and coughing with liquid drops and is introduced into the human body when inhaling air containing infected particles. If the particles are small, they are for some time in the air in the form of an aerosol (drops suspended in the air), and if the particles are larger, then they settle on various surfaces at a distance of up to two meters around the sick person. Very often these are frequent items: door handles, handrails in transport, mobile phones, etc. Touching his face, a person puts the virus on the mucous membranes of the nose, mouth, eye.
Effect of Anemia on Birth Weight among Pregnant Women Attending ANC Clinic at Public Hospitals of Sidama Region, Ethiopia, 2022; A Prospective Cohort Study Protocol
Authors: Tegegne Kaleab Tesfaye , Assefa Abiyu Ayalew , Zenebe Andualem , Bagajjo Wosenyeleh Semeon , Rike Musie , Abebe Alelign Tadele , Assefa Sintayehu
Published: October 2022

Abstract: Background: Anemia is the main cause of morbidity and mortality among pregnant women in developing countries with maternal and fetal consequences, which leads to premature births, low birth weight, fetal cognitive impairment and death. Objective: To establish association between anemia and birth weight among pregnant women attending ANC clinic at public hospitals of Sidama region, Ethiopia, 2022. Methods and Materials: a prospective cohort study design will be conducted from March 1, 2022 to November 30, 2022 in public hospitals of Sidama region. A total of 12 Midwives and 6 supervisors will be involved in the data collection process. Exposed (pregnant women having anemia) and non-exposed (pregnant women not having anemia) will be selected by using simple random sampling technique from the prior three months ANC register of each selected public hospital. The data will be entered into Epidata software and exported to SPSS software for windows version 23 for analysis. Descriptive statistics will be computed and both bivariable and multivariable logistic regression will be employed to assess effect of anemia on birth weight among pregnant women. The output will be presented using adjusted odds ratio (AOR) with the respective 95% confidence interval (CI).
Mechanistic Insight Antidiabetic Potential of Ursolic Acid: In-Silico Molecular Docking
Authors: Ahirwar Priyanka , Malik Jitender K
Published: October 2022

Abstract: Diabetes mellitus is a chief cause involved in the morbidity and mortality among the global population (Steppan et al., 2001). The main event of this syndrome includes elevated blood glucose level (hyperglycemia) followed by polydipsia and polyuria. The secondary complications include retinal damage, loss of kidney function and damage to nerves. Further, the diabetes mellitus will also increase the cardiovascular disease progression. Pentacyclictriterpenes are as well one of the compounds occurring in plants. In this group Ursolic acid is a well-recognized compound that is accessible from various sources like seeds as well as fruits and possess many types of activities and is a bright contender for developing novel treatment approaches for treating diseases. Thus, in the current study, ursolic acid a triterpenoid was selected for evaluation of antidiabetic potential by molecular docking. A mechanistic insight for their antidiabetic potential is elucidating by interaction of ursolic acid with target proteins.
Formulation and Evaluation of Controlled Release Matrix Tablets of Cefixime Trihydrate
Authors: Tambare Rashmi Shivaji , Tapadiya Ganesh G. , Shahi Sadhana R.
Published: October 2022

Abstract: The main objective of the present work was to develop sustained release matrix tablets of Cefixime Trihydrate were prepared by direct compression techniques and evaluates the effect of formulation variables such as lubricant, binder, polymer content and viscosity grades of HPMC on the behavior of Cefixime Trihydrate release. The prepared tablets were evaluated for various physico-chemical parameters. In vitro release profile was check to evaluate the sustained release matrix tablet of Cefixime Trihydrate. The drug release from the optimized formulation was found to follow zero order kinetics. Thus the phenomenon of drug release showed that the release of optimized formulation is controlled by diffusion. Administration of Cefixime Trihydrate in a sustained release dosage would be more desirable for bacterial infections effects by maintaining the plasma concentrations of the drug well above the therapeutic concentration. From In vitro dissolution profile, Formulation S3 was prepared with Hydroxypropyl methylcellulose (K15M) combination where drug release was about 99.14% at the end of 24 hrs and followed zero order with non-Fickian diffusion method. It is selected as the best formulation.
In-Silico Consideration of Anti-Microbial Prospective of Plant Phenolic and Flavonoids
Authors: Kumar Amit , Malik Jitender K.
Published: October 2022

Abstract: Background: Pathogenic microorganism infections pose a serious threat to human health. The need for innovative, safe, and efficient antimicrobial medicines has been driven by rising drug resistance cases, unfavorable antibiotic side effects, and the reemergence of previously identified illnesses. Virtual screening techniques used in drug development, such as drug-likeness and ADMET analysis, use computation to quickly and cheaply identify compounds that are likely to demonstrate physiological activity. Methods: In this regard, the enzyme aminoacyl-tRNA synthetase (AaRS) has been the focus of recent research in the discovery of antibacterial agents. Docking studies were performed Molecular docking of aminoacyl-tRNA synthetase (AaRS) with chlorogenic acid, rutin, quercetin and gallic acid was carried out by AutoDock. Results: The molecular docking result revealed that chlorogenic acid, gallic acid, quercetin and rutin showed encouraging docking score. Hence from above finding it can be predicted that phenolics and flavonoids found in the plants extract exhibited good inhibitor of IleRS enzyme.
Bitterleaf (Venonia amygdalina) and Water leaf (Talinum triangulare) in Pullets Nutrition: Effects on Blood Vitamins and Minerals
Authors: Igene F. U.
Published: October 2022

The effect of bitter leaf (Venonia amygdalina) and water leaf (Talinum triangulare) extracts on blood vitamins and minerals composition of pullet birds were investigated. A total of 456 day-old Isa brown pullet chicks were allotted to four dietary treatments in six replicates in a completely randomized design experiment. Aqueous extracts of bitter leaf and water leaf were used as test dietary treatments for the birds. In treatment 1, a commercial multivitamin (vitalyte) was given in water (1g/L) to the birds to serve as the control. In treatments 2 and 3 aqueous extracts of bitter leaf and waterleaf were given at 100ml/L of water, while in treatment 4 mixed bitter leaf and water leaf aqueous extract (50% each in composition) was given. On the last day of the feeding trial, blood samples were collected from the birds for vitamins and minerals analysis. The observed results showed that dietary treatments significantly affected the blood serum parameters. Vitamin A was significantly higher (P < 0.05) in the vitalyte birds. The values ranged from 0.27iu in the bitter leaf birds to 0.37iu in the vitalyte. Vitamin C was more abundant (1.84iu) in the bitter leaf treated pullets and was significantly reduced (1.21iu) in the vitalyte. Vitamin D was significantly (P < 0.05) higher (0.35 iu) in the water leaf as well as vitamin E (10.14iu) while they were highly reduced considerably in the vitalyte administered birds, 0.16 and 4.83iu respectively. On mineral composition, while bitter leaf was the highest Ca (14.24mg/dl) source, K (5.46 mmol/L) and Mg (2.78mg/dl) were highly increased in the water leaf administered birds. Pullets on the control vitalyte had higher Na (132.75 mmol/L) and Fe (1.42g/dl). It can however be concluded that bitter leaf and water leaf as used in this study are potential sources of some vitamins and minerals in pullet chick nutrition.
Stance and Engagement Markers in The Jakarta Post's Opinion Articles
Authors: Angela Christine
Published: October 2022

A number of research has currently established that written texts represent interactions between writers and readers. A range of linguistic features have been identified as a contribution to the author’s projection of a stance to the material referenced by the text, and, to further extent, the strategies used to presuppose the active role of an addressee. Based on the investigation of ten (10) English written opinion articles published by The Jakarta Post, this study used a qualitative case study approach. This study attempted to address the stance and engagement markers used in the opinion-ed writers page written in English using stance and engagement theory proposed by Hyland (2005) as its framework. This model shows a comprehensive and integrated way of analyzing the means by which interaction is achieved in opinion argument and how the discoursal preferences of disciplinary communities’ construct both writers and readers. Findings show that the interaction is adequately appropriate. The use of stance markers and engagement markers is not necessarily balanced. The study found that the stance markers is used more often than the engagement markers. The writers could have been used more innovatively. The overall findings of the study have both pedagogical and future research implications.
Utilization of Student Worksheets (LKPD) to Develop Independent Learning During the Covid-19 Pandemic (Qualitative Research on Grade 6 Students)
Authors: Halimatusadiah Sifa
Published: October 2022

The aims of this study are:, to describe how students learn through the use of LKPD during the Covid-19 period,  to describe the efforts made by parents in developing learning independence during the pandemic through the use of LKPD, and to describe the efforts made by teachers in developing independence. learn students during the pandemic by using LKPD. This study uses qualitative research methods using a qualitative descriptive approach. Data collection techniques and procedures used structured observation and semi-structured interviews. The results showed that in using LKPD during the Covid-19 period, teachers were able to understand the benefits of LKPD to help the learning process during the pandemic. The use of LKPD in learning is considered very effective because with LKPD students can study independently at home or at school. Then, the role of parents in learning during this pandemic is very helpful. However, there are still many parents who do not understand the important role of parents in accompanying their children to study at home.
Application of Contextual Teaching and Learning Model to Mathematical Communication Ability
Authors: Sukma Wa Ode Nurmala , Rukli Rukli , Syamsuddin Agustan
Published: October 2022

The purpose of this study was to determine the effect of the contextual teaching and learning model on students' mathematical communication skills. This study uses quasi-experimental design research in the form of a time-series design. The population is all fourth-grade students of Madrasah Ibtidaiyah (MI) in Sorong City for the 2021/2022 academic year. The sampling technique used cluster random sampling, with a sample size of 30 students of MI Al-Ma'arif Sorong City. The data analysis technique in this study used the paired sample t-test. The results showed that there was a significant influence from the application of the contextual teaching and learning model on students' mathematical communication skills.
Technological Pedagogical Content Knowledge (TPACK) Profile Elementary School Teachers on Geometry Materials Judging from Teaching Experience
Authors: Idrus Ridwan Laode , Baharullah Baharullah , Saleh Sitti Fithriani
Published: October 2022

This study aims to describe the teacher's TPACK profile on geometry material in terms of teaching experience in each TPACK component consisting of: (1) Kindergarten; (2) CK; (3) PK; (4) TPK; (5) TCK; (6) PCK; and (7) TPACK. This research was conducted at SD Negeri Sungguminasa IV, Gowa Regency using a qualitative descriptive method with data collection techniques through observation and interviews with experienced and novice teachers. The results of the study show that: (1) TK beginners and experienced teachers have the same ability to understand and utilize technology; (2) CK for beginners and experienced teachers have not mastered the geometry material well; (3) PK novice teachers and experienced teachers there are differences in the application of learning methods; (4) TPK for novice teachers and experienced teachers have the same ability to use technology in learning activities; (5) TCK beginner teachers and experienced teachers have the same ability and are good at utilizing technology to present learning materials; (6) PCK novice teachers and experienced teachers have differences in the application of learning methods, beginners use the lecture method monotonously, while experienced teachers use more varied methods; and (7) TPACK for novice teachers and experienced teachers, there are differences in the application of learning methods, such as the ability of PK and PCK.
The Influence of the Use of Google Meet with the Assistance of Google Classroom on Interest and Learning Outcomes of Mathematics in Class V Students of Ipeka Christian Elementary School Makassar
Authors: Mentaruk Desriani , Baharullah Baharullah , Husniati Andi
Published: October 2022

This research aimed to analyze the impact of Google Classroom assisted by Google Meet use on the interests and learning outcomes of students' mathematics  Class V Kristen Elementary School. This type of research was quantitative research with quasi-experiment. The research design used was a non-equivalent control group design.  The population in this study were the students of class V of Kristen Elementary School IPEKA Makassar, with a total of 60 students divided into two classes, VA and VB.  Va class was the experimental class, and VB class was the control class. The technique of data collection was using tests and learning interests. Data analysis techniques in research used descriptive and inferential statistical analysis. Based on the data analysis, the average learning interest of experimental class students was 73.33, and control classes were 59.33. In addition, classically the interest in learning experimental classes reached  80%. The average results of experimental math learning classes were 93 while the average results of learning math control classes were 69.67. In addition, the completion of classical learning experimental classes reached 100%. The N-Gain Test obtained a coefficient of 0.841 and was categorized as high. Test the hypothesis using an independent sample t-test.  In statistical analysis, learning interests were obtained sig value. (2-tailed) = 0.00 < 0.05. In the analysis of post-test results of learning results obtained Sig values. (2-tailed) = 0.032 < 0.05. From the data, it can be concluded that the use of Google Meet assisted by Google Classroom affected the interests and results of learning mathematics students of class V Kristen Elementary School IPEKA Makassar.
Development of E-Module Teaching Materials on the Role of Economic Activity Actors for Class X IPS 1 Students at SMAN 1 Cerme
Authors: Jannah Roudlotul , Rafsanjani Mohammad Arief
Published: October 2022

This study aims to develop teaching materials for the application of e-modules on the role of economic actors in terms of feasibility, practicality and effectiveness in order to improve student learning outcomes on the material on the role of economic actors in economic activities independently. This study uses the ADDIE development model (Analysis, Design, Development, Implementation, Evaluation). The trial of teaching materials was limited to class X IPS 1 at SMAN 1 Cerme with a total of 36 students. Based on the results and analysis, the average value of the total validity of teaching materials is 3.5 (material expert) and 3.6 (graphic expert). The average validity is 3.55 with a very valid category. The average value of the total practicality of teaching materials is 99.5% in the very practical category and the average value of the total effectiveness of teaching materials is 97% of the total students who get learning outcomes above the classical completeness score of 75 points (determined KKM). teaching materials for the application of e-modules on the role of economic actors can be said to be effective.
The Effect of Seating Management on Students' Motivation and Learning Outcomes for Social Studies Subject Class V at MI Somba Opu District, Kab. Gowa
Authors: Ismail Muliana , Abdul Aziz Muslimin , Hidayah Quraisy
Published: October 2022

This study aims to determine the significant effect of seating management on the motivation and learning outcomes of students in Social Studies subject in class V at MI Somba Opu District, Gowa Regency. This type of research is quantitative research with True Experiment Design with pre-test, post-test control group design. The population of this study was MI Somba Opu District. The samples in this study were students of Class V at MI Madani Alauddin and MI Ash Salihin, Gowa Regency, totaling 50 students. The data collection technique used is the provision of questionnaires and taking student learning test results, the value of the acquisition of student learning motivation after being given treatment is 68.28 and student learning outcomes are 80. Based on the results of the questionnaire given to students and student learning outcomes obtained, it proves that motivation and student learning outcomes in the experimental class are higher than the control class, this is because the experimental class is given treatment using several seating placement models so that students are more motivated and learning outcomes increase during the learning process compared to the control class which only uses a seating management model. conventional or in a row. The significant value is less than 0.05, so it can be concluded that there is an effect of seating management with several models on the motivation and learning outcomes of students in Social Studies subject in Class V at MI Somba Opu District, Gowa Regency. This research is expected that teachers can maximize the management of the main class in terms of student seating management by applying several models to increase student motivation and learning outcomes.
The role of government digital media in enhancing Emirati soft power (An analytical descriptive study)
Authors: ALHAMMADI ADNAN HAMAD , AWAIS DR. IHAB AHMED
Published: October 2022

The research paper aims to review the concept of soft power and its importance, its role and its ability to spread and influence, which has a great impact on the United Arab Emirates in extending its influence and high standing externally. beliefs and respect for others. Knowing how to change all these resources, capabilities and initiatives, especially the humanitarian and charitable aspect of them through government digital media, and export it to the outside world, with which the state acquires an international position that makes it in the ranks of a developed country is the main goal on which this research paper is built, considering that the UAE is one of the most The countries of the region, as a contribution to charitable projects, and for justice and their adoption of the concept of tolerance as a general thought, the digital government media sought to adopt and root it in their people and present lofty messages represented by the soft power that is embodied in international initiatives to the countries of the other world.
Provisions of Disciplinary Sanctions in Islamic Jurisprudence
Authors: Mohammad Dr.fatma Essa
Published: October 2022

We note the large spread of cases of administrative corruption, bribery and nepotism among workers in different sectors, and that holding workers accountable and following them up, makes them keen to make effort and take responsibility, and maintain the principles of functional behavior that they have pledged, and in the event of transgression and violation of these principles, disciplinary penalties and deterrent penalties approved by Islam is a protection for public money and to prevent fraud and the spread of corruption, in order to achieve justice and safety in the Muslim community.
The problem of the research lies in the large spread of administrative corruption in Muslim societies, despite the application of man-made laws, and the laxity of workers in committing violations in the absence of a deterrent penal system,
so this research was to answer the following questions: On the workers, and what are the legal evidences on their application, and what are the legitimate purposes of applying disciplinary sanctions. The aim of the research: The research aims to highlight the most important disciplinary provisions in Islamic jurisprudence, and to clarify the sayings of jurists in them and the relationship of these provisions with legitimate purposes, and the impact of the application of these provisions on community development.
The importance of the research:
The research is concerned with highlighting the relationship between the application of disciplinary provisions to workers and community development, and clarifying the areas of application of jurisprudence rules in disciplinary sanctions and their role in spreading safety and eliminating administrative corruption.
Research Methodology:
I used the inductive method in the research in addition to the descriptive analytical method in viewing and summarizing, Including: the necessity of applying Sharia disciplinary provisions, preventing the appointment of abnormal groups in Muslim societies, working to achieve justice and spreading safety to achieve development in society, observing sincerity and honesty in following up on workers, looking into the grievances of workers and dealers to prevent harm to others, employing modern technologies and the virtual world in Deter the excesses of workers and administrators alike The research concluded with a list of sources and references.
Keywords: disciplinary, provisions, legitimacy, rules, jurisprudence, purposes, corruption, development.
The status of language immersion in Arabic instruction for non-native speakers - virtual class as a model
Authors: EL Batri Hamid
Published: October 2022

The teaching and learning of Arabic to by non-native speakers has undergone a number of rapid and successive developments, including the emergence of new interactive, pedagogical patterns that tend to keep pace with enormous advance in the use of technology. In this field, the educational process inevitably has moved from traditional in-person interaction to distance education in a virtual class.
Owing to this interactional change, in which virtual environment is a dominant one, the element and the role of language immersion in foreign Arabic learning has become completely absent. As a consequence, only abstract content is left for the learner, lacking substantial opportunities for practice, immersion, and cultural in-context use of language.
Accordingly; this paper intends to answer the following questions:
- To what extent has Arabic language immersion been achieved for non-speakers in distance education?
- If there were the so-called virtual immersion present in distance, where exactly would the language partner’s role emerge?
- How does modern technology be come in handy, being of considerable use for language immersion?
Keywords: language immersion, virtual class, language partner, Arabic for non-native speakers
Rancangan Strategi Kolaborasi Pengembangan UMKM Kripik “ASA” Menggunakan Metode SWOT
Authors: Firmansyah Mokhamad Rizky , Rosyida Erly Ekayanti , Puspitorini Pipit Sari
Published: October 2022

Abstrak: Penelitian ini bertujuan untuk mengetahui untuk mengetahui faktor – factor kekuatan, peluang, kelemahan, ancaman pada UMKM ASA dan menenentukan strategi kolaborasi yang optimal dalam pengembangan dan meningkatkan daya saing UMKM keripik ubi “ASA”. Informasi yang dipilih adalah UMKM Keripik Ubi “ASA” di Desa Sajen Kecamatan Pacet. Analisis yang di gunakan adalah analisis SWOT dan penelitian riset sistem informasi dari Havner dkk. (2004).Hasil penelitian menunjukkan bahwa :1 Startegi Pengembangan UMKM keripik ubi “ASA” yang harus di terapkan oleh usahanya : Menjaga kualitas produk keripik ubi yang berbahan baku alami berkualitas tinggi dan bergizi untuk memenuhi permintaan keripik ubi jalar, melakukan perbaikan sistem manajemen industry, memperkuat jaringan dan meningkatkan pemasaran, melakukan pengoptimalan biaya produksi, mengupayakan ketersedian bahan baku secara berkelanjutan, melakukan pengembangan pada produk. 2 Perancangan strategi kolaborasi ada 3 antara lain : kolaborasi klaster industry sesama UMKM kripik, kolaborasi upstream dan dwonstream, kolaborasi kopetensi.

Kata kunci: Analisi SWOT , Strategi Pengembangan, Kolaborasi
Model Pengendalian Food Waste Pada Supermarket Dengan Menggunakan Sistem Dinamik
Authors: Cahyono Rizki Andi , Cahyana Atikha Sidhi
Published: October 2022

Food waste adalah masalah yang sedang dihadapi diberbagai negara khususnya di indonesia Super market sebagai tempat penghujung pada rantai pasok makanan sering kali menghasilkan sampah berupa sampah makanan. Oleh karena itu, ini adalah target yang berpotensi baik untuk langkah-langkah pengurangan sampah makanan yang dihasilkan oleh supermarket, meskipun supermarket menyumbangkan porsi sampah makanan yang relatif kecil.Penelitian ini akan dilakukan di kecamatan Porong kabupaten Sidoarjo. Penelitian ini merupakan gabungan antara studi eksploratif dan pengembangan model. Penelitian ini melakukan pendekatan dengan sistem dinamik untuk menampilkan permasalahan yang yang terjadi pada supermarket. Dari masalah tersebut pendekatan sistem dinamik dan pengembangan model melalui software stella Dari hasil analisa dan pengolahan data dapat ketahui banyaknya food waste buah slice sebesar 51kg dan fried chiken sebanyak 42pcs dengan  kerugian akibat food waste tersebut sebesar Rp2.053.281,00. Kemunculan food waste dipengaruhi oleh beberapa faktor dan kebijakan toko untuk pengendalian food waste masih kurang
Inovasi Tas Kasual Dari Kanvas Dengan Aksen Ulap Doyo Untuk Remaja Laki-Laki Dengan Pendekatan 6 Fase Pengembangan Produk
Authors: Rahmitasari Ananda , Soeprapto Etwin Fibrianie , Nizaora Ditha
Published: October 2022

Indonesia memiliki beragam kain tenun tradisional dengan ciri khas yang unik. Salah satu produk tekstil tradisional tersebut adalah tenun Ulap Doyo. Pelestarian Tenun Ulap Doyo dimasa sekarang ini sudah mulai diminati oleh masyarakat di dalam negeri maupun dari luar negeri, namun masih banyak masyarakat yang tidak mengetahui Tenun Ulap Doyo ini khususnya di kalangan anak muda. Tujuan perancangan produk ini adalah bagaimana memperkenalkan kain tenun khas kebudayaan lokal Kalimantan Timur kepada anak muda zaman sekarang. Perancangan ini menggunakan pendekatan 6 fase perancangan produk, yakni Fase Perencanaan, Pengembangan Konsep, Perancangan Tingkat Sistem, Fase Perancangan Detail, Pengujian dan Perbaikan, dan Fase Produksi. Ulap Doyo yang biasanya digunakan untuk acara adat, akan dihadirkan lebih kekinian sehingga dapat diterima di kalangan anak muda dan diharapkan dapat menjadi media pengenalan Ulap Doyo kepada masyarakat luas dalam bentuk produk desain berupa tas kasual untuk remaja laki-laki. Tas Kasual ini merupakan tas yang cocok untuk dibawa saat berpergian dan berkumpul dengan kerabat. Maka tas ini akan menjadi salah satu sarana pengenalan budaya sekaligus alat bantu bawa yang memenuhi kebutuhan aktivitas target utama pasar.
Analisis Risiko pada Rantai Pasok Tembakau
Authors: Rosyida Erly Ekayanti , Susanti Aliyah , Sholikha Nur Kholifatus , Puri Wuwuh Asrining
Published: October 2022

Tembakau merupakan salah satu jenis komoditas perkebunan yang permintaannya tinggi. Tingginya permintaan tembakau linier dengan tingginya permintaan rokok karena sebagian besar tembakau dipasokkan pada industri rokok yang permintaannya selalu tinggi. Industri rokok merupakan salah satu bagain hilir dari rantai pasok tembakau. Rantai pasok tembakau terdiri dari petani tembakau, supplier bahan untuk tanam dan produksi tembakau, pengepul,agen,dan industri rokok. Permasalahan yang terjadi dalam industri rokok adalah kegagalan dalam memenuhi permintaan dan turunnya keuntungan yang diperoleh dikarenakan turunnya harga jual tambakau. Penelitian ini melakukan kajian untuk menganalisis risiko yang menyebabkan tidak terpenuhinya permintaan dan turunnya keuntungan yang diperoleh melalui analisis risiko pada rantai pasok tembakau. Identifikasi risiko pada rantai pasok tembakau dengan menentukan terlebih dahulu sumber risikonya yang didasarkan pada model SCOR yang terdiri atas Plan, Source, Make, Deliver dan Return. Kelima elemen tersebut dijadikan sebagai sumber risiko yang kemudian dari sumber risiko (risk identity) tersebut dianalisis kejadian risiko (risk event) beserta dampaknya. Tahapan selanjutnya adalah penilaian risiko dari terhdap kemungkinan terjadi risiko tersebut beserta dampak yang diakibatkan
Location and characterization of the Misiones plinthite (Argentina)
Authors: Vigo D. A. , Siviero N. R. , Schvezov Carlos E.
Published: October 2022

Plinthite (Gr. Plinthos, brick) is a residual soil that occupies 60 million hectares on the planet. The Province of Misiones (Argentina) is the border zone of South America where this soil appears, locally called in its cemented state or petroplinthite as itácurú (stone toad in the Guarani language). Four centuries ago, it was used in the form of blocks cut from nearby deposits for the construction of the Jesuit reductions since 1601 in Loreto. Since then, there is a time jump until it is used in the construction of Coastal Route No. 2. In view of its potential and in the absence of systematic studies, this report aims to promote this mining resource for the restoration of reductions, constructions allegorical and road use. To this end, prospecting has been carried out in search of new deposits and others previously exploited that have been detected and evaluated; some used by the Jesuits. The location, size and approximate power of each of the explored deposits are presented, as well as the geotechnical values.
The experimental results of the physical-mechanical properties and the effects on the properties of the different drying/wetting cycles carried out are presented and analyzed.
Computational Environment for Genomic Sequencing and Annotation: a workflow for application in projects by life researchers
Authors: Pedron Cassol Matheus , Lenz Alexandre Rafael , Zacaria Rudinei , de Avila e Silva Scheila
Published: October 2022

The current paper seeks to approach, using a workflow, basics subjects of the bioinformatic field and also useful informations to consider during the development of in silico researches. Installation and general usage of multiple softwares related to different sections of the genome annotation process were also presented. At last, an model organism, Staphylococcus aureus, was sequenced in two different softwares, SPAdes and IDBA-UD, seeking further comparison and evaluation of the process as a whole. The quality evaluation of the assemble was established by tests on QUAST, BUSCO and Augustus, supported by BLASTP. Results: QUAST evaluation returned genome coverage values above 98% in both test cases, pointing towards a trustworthy assemble for this organism. Via SPAdes were needed less computational resources, but, using IDBA-UD the sequences found were more contiguous. Results deriving from BUSCO showed only one expected gene difference. Some proteins and genes predicted by Augustus led to hits, sequences already studied in that organism, using the BLASTP program.
Stem rot (Sclerotium oryzae) in rice crops on the southern region of Paraguay
Authors: Quintana L. , Gutiérrez S. A.
Published: October 2022

The expansion of rice cultivation in Paraguay observed in the last five agricultural seasons, together with the new technologies applied, has been accompanied by an increase in the presence of diseases affecting rice leaf sheaths and stems. In view of the scarcity of information in the country on some of these diseases, this study was carried out to characterise rice stem rot. Samples of symptomatic plants were collected from commercial lots located in the southern region of the country, and routine techniques in plant pathology for the study of mycoses were applied, such as macro and microscopic observations, in vitro sowings, and the study of morphological and cultural characteristics of the fungus. The pathogenicity of the fungus was determined by inoculations on healthy 50-day-old rice plants. Associated with the symptoms observed on rice pods and stems, the fungus Sclerotium oryzae Catt was identified as causing irregular black lesions on the leaf sheaths at the water line. As the disease progressed, it caused lesions on the sheaths and leaf blades, and finally stem rot with the formation of sclerotia inside the affected stems. The symptomatology observed in the rice plants and the cultural and morphometric characteristics of the pathogen Sclerotium oryzae were consistent with those reported in the bibliographical references analysed.
Strategi Meningkatkan Literasi Masyarakat atas Program Penjaminan Simpanan oleh LPS
Authors: Saefullah Aep , Hajar Elvira Sitna , Zainuddin Zulkifli
Published: October 2022

Penelitian ini bertujuan untuk mengetahui bagaimana strategi dan langkah dalam meningkatkan literasi masyarakat terhadap program Lembaga Penjamin Simpanan. Metode yang digunakan dalam penelitian ini menggunakan pendekatan kualitatif. Teknik pengambilan sample penelitian ini menggunakan teknik Simple Random Sampling sebanyak 150 reponden Teknik pengumpulan data diambil melalui observasi, analisis visual, studi pustaka, dan interview. Hasil penelitian menunjukkan bahwa 1. Masyarakat masih banyak yang belum mengetahui dan memahami tentang program-program, tugas, fungsi dan kewenangan Lembaga Penjamin Simpanan (LPS). 2. Masyarakat mendapatkan informasi tentang program-program penjaminan Lembaga Penjamin Simpanan (LPS) melalui website dan media sosial atau datang langsung ke Bank terdekat. Meminta penjelasan informasi secara langsung di kantor LPS atau perwakilan di daerah.  selain itu melalui sosialisasi kegiatan baik luring tatap muka maupun daring (online). 3. Langkah dan strategi untuk meningkatkan literasi masyarakat terhadap program penjaminan LPS antara lain a) Sosialisasi program kepada masyarakat yang intensif baik offline mapun online berupa seminar, workshop,webinar dll. b) Perlunya keterlibatan elemen masyarakat (Perguruan Tinggi, Ormas, LSM) dan stake holder lembaga keuangan perbankan maupun non keuangan. c) LPS menjemput bola datang langsung ke sentra titik kumpul masyarakat guna mengenalkan lembaga. d) Optimalisasi media sosial LPS di berbagai platform. e) Meningkatkan kepercayaan publik sebagai pembuktian dan capaian kinerja LPS. f) Membuat aplikasi digital yang mudah diakses masayarakat. g) Membuat selebaran poster yang disebarkan dikantor lembaga keuangan perbankan dan non perbankan.
Facebook dan Pembelajaran Bahasa: Pengalaman Pembelajar dalam Belajar Tata Bahasa Inggris Menggunakan Grup Facebook
Authors: Pujawa Prabawa Wawa
Published: October 2022

Orang merasa bahwa teknologi web 2.0 dan situs jejaring sosial (SNS), khususnya Facebook, sangat erat kaitannya untuk digunakan dalam program pendidikan sebagai sarana pembelajaran, terutama untuk tujuan belajar mengajar bahasa Inggris. Sebaliknya, telah dilihat sebagai cara bagi siswa untuk melengkapi pendidikan formal mereka dengan melakukan penelitian dan membaca artikel di luar kelas. Yang Saya Suka Tentang Facebook, bisa buat grup belajar, Dr Grammar contohnya. Ini adalah grup Facebook untuk pelajar yang ingin belajar tata bahasa Inggris. Studi ini mengeksplorasi Facebook dan pembelajaran bahasa dalam konteks pengalaman pembelajar dalam belajar tata bahasa Inggris menggunakan Dr. Grammar. Mengadopsi pendekatan studi kasus kualitatif, melibatkan enam belas peserta yang mendaftarkan Dr. Grammar melalui kuesioner dan wawancara. Tanggapan terhadap butir-butir skala Likert dianalisis dengan menggunakan persentase tanggapan frekuensi, sedangkan untuk menghasilkan analisis yang lebih mendalam digunakan wawancara semi-terstruktur untuk mendapatkan tanggapan peserta. Hasil penelitian menunjukkan bahwa peserta didik mengalami sikap positif terhadap grup Facebook dalam pembelajaran grammar melalui Dr. Grammar. Penelitian ini menyarankan bahwa peserta didik harus mampu untuk tidak bergantung pada guru itu sendiri, mereka diperbolehkan untuk belajar dan mengeksplorasi penggunaan teknologi dan jejaring sosial dalam menumbuhkan kemandirian peserta didik dalam proses pembelajaran.
Traumatic Internal Carotid Artery Aneurysm with a Concomitant Carotid Cavernous Fistula
Authors: Ibrahim Muhammad Imran , Nisar Tayyaba , Tanveer Ayesha , Sohail Sundus , Khan Rehman , . Ahmed
Published: October 2022

Post-traumatic sphenoid sinus pseudoaneurysm arising from the cavernous segment of the internal carotidartery (ICA) is rare, and even rarer occurrence is an associated carotid-cavernous fistula (CCF). Here we presentthe case of a young male patient presenting with intractable epistaxis due to a post-traumatic sphenoid sinuspseudoaneurysm of the internal carotid artery and a simultaneous carotid-cavernous fistula.

How to cite this: Ibrahim MI, Nisar T, Tanveer A, Suhail S, Khan R, Ahmed. Traumatic Internal Carotid Artery Aneurysm with a Concomitant Carotid Cavernous Fistula. Life and Science. 2022; 3(4): 200-202. doi: http://doi.org/10.37185/LnS.1.1.252
Important aspects during management of diabetic foot infection
Authors: García Klepzig José Luis , Azaña Gómez Javier , Méndez Bailón Manuel
Published: October 2022

Diabetic foot is a complex disease. One of its most important complications is infection with risk of limb loss. In severe cases it is also a life-threatening condition. Several guidelines are available in order to achieve the implementation of some standard of care strategies. However, these consensus documents do not address all controversial issues arising during diabetic foot infection. The present article aims to review some of these controversial aspects.
COVID-19 in donation and transplant
Authors: Candel Francisco Javier , Pardo Rey Cándido , Torres-González Juan Ignacio , Fernández-Vega Paula , Fragiel Marcos , Oteo David , del Toro Enrique , Vega-Bayol Mónica , Outon Cristina , Encabo Marta , García-Marugán Agustín , Resino Sara , Parra Dolores , Matesanz Mayra , del Rio Gallegos Francisco J.
Published: October 2022

SARS-CoV-2 infection has had a major impact on donation and transplantation. Since the cessation of activity two years ago, the international medical community has rapidly generated evidence capable of sustaining and increasing this neccesary activity. This paper analyses the epidemiology and burden of COVID-19 in donation and transplantation, the pathogenesis of the infection and its relationship with graft-mediated transmission, the impact of vaccination on donation and transplantation, the evolution of donation in Spain throughout the pandemic, some lessons learned in SARS-CoV-2 infected donor recipients with positive PCR and the applicability of the main therapeutic tools recently approved for treatment among transplant recipients.
Diagnostic and therapeutic approach to pulmonary infiltrates in cancer patients receiving immune checkpoint inhibitors
Authors: Fernández-Ruiz Mario
Published: October 2022

The advent of immune checkpoint inhibitors (ICIs) targeting cytotoxic T lymphocyte antigen 4 (CTLA-4) and the programmed cell death (PD-1)/PD-1 ligand 1 (PD-L1) axis has transformed the treatment paradigm for multiple cancer types. ICIs are able to restore T-cell-mediated antitumor responses and do not entail an increased risk of infection per se. However, immunotherapy is associated to a unique form of toxicity due to the off-target effects on healthy tissues of the excessively enhanced immune response in form of immune-related adverse events (irAEs). Although ICI-induced pneumonitis ranks the fifth of all irAEs in terms of frequency of occurrence, it is associated with a relevant attributable mortality. This review summarizes the incidence, risk factors, clinical and radiological presentation, and therapeutic approach of ICI-induced pneumonitis. Particular focus is on the differential diagnosis of new or worsening pulmonary infiltrates in cancer patients receiving ICI therapy. Finally, the impact on the risk of opportunistic infection of ICIs and immunosuppressive therapy used to treat associated irAEs is reviewed. The diagnosis and management of suspected ICI-induced pneumonitis remains clinically challenging.
Mobile Application for Enhancing Revenue Collections in Local Government Authorities. A Case of Tanzania
Authors: Njogela Elia , Ally Juma , Lufyagila Beston , Ruabo Francis
Published: October 2022

Point of Sale terminals play a significant role in revenue collection and have become rampant to Tanzanian Local Government Authorities. Point of Sale systems monitors cash flow, transactions, and price control while reducing human error and managing staff, customers, and inventory. However, Point of Sale systems are vulnerable to fake receipts, thus reducing revenue collections among Local Government Authorities. The cross-sectional Design was used to facilitate knowledge for the subsequent data collection. Data were collected from 300 respondents in Mbeya and Songwe regions using purposive and simple random sampling. 70% of respondents reported that fake receipt is the major factor affecting revenue collection, followed by lack of training (20%) and security (8%). In this study, we propose a mobile-based solution to enhance revenue collection in Local Government Authorities by addressing major factors affecting revenue collection. The developed mobile application was evaluated and validated; Whereby the results confirm that the designed tool is effective against money fraud, transaction errors, human errors, and defaulters with minimal resource usage. Hence, the designed mobile application can be applied as an auditing tool to reduce money fraud and increase revenue collection for the Local Government Authorities