bluuebunny/crossref_metadata_2025 huggingface dataset:
Three-Dimensional Mathematical Model of the Liquid Film Downflow on a Vertical Surface
Authors: Pavlenko Ivan , Liaposhchenko Oleksandr , Ochowiak Marek , Olszewski Radosław , Demianenko Maryna , Starynskyi Oleksandr , Ivanov Vitalii , Yanovych Vitalii , Włodarczak Sylwia , Doligalski Michał
Published: April 2020

Film downflow from captured liquid without wave formation and its destruction is one of the most important aspects in the development of separation equipment. Consequently, it is necessary to create well-organized liquid draining in areas of captured liquid. Thus, the proposed 3D mathematical model of film downflow allows for the determination of the hydrodynamic parameters of the liquid film flow and the interfacial surface. As a result, it was discovered that the interfacial surface depends on the proposed dimensionless criterion, which includes internal friction stress, channel length, and fluid density. Additionally, equations for determining the averaged film thickness, the averaged velocity vectors over the film thickness, the longitudinal and vertical velocity components, and the initial angle of streamline deviation from the vertical axis were analytically obtained.
A Piezoelectric Harvesting Interface with Capacitive Partial Electric Charge Extraction for Energy Harvesting from Irregular High-Voltage Input
Authors: Khan Muhammad Bilawal , Saif Hassan , Lee Yoonmyung
Published: April 2020

A fully integrated piezoelectric energy harvesting interface is proposed for harvesting energy from irregular human motion. To handle irregular pulse inputs generated by the piezoelectric transducer (PZT), the proposed harvesting interface includes a wake-up controller that activates the harvesting interface only when human motion is detected and deformation is applied on the piezoelectric material, thereby keeping static power loss low. The PZT output voltage is increased to its peak voltage by removing any type of external load capacitance seen by the PZT during its deformation. Once the peak voltage is detected, a multi-voltage conversion-ratio-based switched-capacitor circuit is activated to transfer PZT-generated energy to the battery in multiple ratio steps to maximize the conversion efficiency, with the help of a carefully designed harvesting controller. To deal with open-circuit voltages (VOCS) higher than the maximum voltage tolerated (VMAX) by available technology, capacitive partial electric charge extraction is activated every time the PZT output voltage approaches the VMAX. The proposed harvesting interface extracts 3.37 times more energy than a conventional full-bridge rectifier-based harvesting scheme.
A Method to Introduce Building Performance Simulation to Beginners
Authors: Gentile Niko , Kanters Jouri , Davidsson Henrik
Published: April 2020

Competence in performing Building Performance Simulations (BPS) is a fundamental asset for an energy specialist. However, teaching BPS to new students can be challenging, often due to the overwhelming capabilities of the software. The consequences for students are frustration and lack of confidence using the software, dividing group work based on previous expertise and, most importantly, the inability to predict and critically analyse results due to the superficial understanding of simulations. This paper presents and evaluates a simple method named ‘control method’ which is intended to introduce BPS in classes where students have a limited experience working with BPS, significantly different educational backgrounds, and where the time to teach BPS in class is limited. The method is built around the Structure of Observed Learning Outcomes taxonomy. It aims to provide the students with a basic understanding of the input-output relationship between parameters, prompting the use of BPS independently during their individual study time. The application of the method is evaluated with two survey-based studies. The findings suggest that the method prompts higher level thinking in BPS and collaborative learning in groups. Further investigation is needed to verify if students’ ability to predict results is also increased.
Thermal Analysis of Power Rectifiers in Steady-State Conditions
Authors: Plesca Adrian , Mihet-Popa Lucian
Published: April 2020

Power rectifiers from electrical traction systems, but not only, can be irreversibly damaged if the temperature of the semiconductor junction reaches high values to determine thermal runaway and melting. The paper proposes a mathematical model to calculate the junction and the case temperature in power diodes used in bridge rectifiers, which supplies an inductive-resistive load. The new thermal model may be used to investigate the thermal behavior of the power diodes in steady-state regime for various values of the tightening torque, direct current through the diode, airflow speed and load parameters (resistance and inductance). The obtained computed values were compared with 3D thermal simulation results and experimental tests. The calculated values are aligned with the simulation results and experimental data.
Combined Optimal Design and Control of Hybrid Thermal-Electrical Distribution Grids Using Co-Simulation
Authors: Widl Edmund , Leitner Benedikt , Basciotti Daniele , Henein Sawsan , Ferhatbegovic Tarik , Hofmann René
Published: April 2020

Innovations in today’s energy grids are mainly driven by the need to reduce carbon emissions and the necessary integration of decentralized renewable energy sources. In this context, a transition towards hybrid distribution systems, which effectively couple thermal and electrical networks, promises to exploit hitherto unused synergies for increasing efficiency and flexibility. However, this transition poses practical challenges, starting already in the design phase where established design optimization approaches struggle to capture the technical details of control and operation of such systems. This work addresses these obstacles by introducing a design approach that enables the analysis and optimization of hybrid thermal-electrical distribution systems with explicit consideration of control. Based on a set of key prerequisites and modeling requirements, co-simulation is identified as the most appropriate method to facilitate the detailed analysis of such systems. Furthermore, a methodology is presented that links the design process with the implementation of different operational strategies. The approach is then successfully applied to two real-world applications, proving its suitability for design optimization under realistic conditions. This provides a significant extension of established tools for the design optimization of multi-energy systems.
Modeling Height–Diameter Relationship for Poplar Plantations Using Combined-Optimization Multiple Hidden Layer Back Propagation Neural Network
Authors: Shen Jianbo , Hu Zongda , Sharma Ram P. , Wang Gongming , Meng Xiang , Wang Mengxi , Wang Qiulai , Fu Liyong
Published: April 2020

Relationship of total height and diameter at breast height (hereafter diameter) of the trees is generally nonlinear, and therefore has complex characteristics, which can be accurately described by the height-diameter model developed using the back propagation (BP) neural network approach. The multiple hidden layered-BP neural network has several hidden layers and neurons, and is therefore considered more appropriate modeling approach compared to the single hidden layered-BP neural network approach. However, the former approach is not widely applied for tree height prediction due to absence of the effective optimization method, but it can be done using the BP neural network modeling approach. The poplar (Populus spp. L.) plantation data acquired from Guangdong province of China were used for evaluating the BP neural network modeling approach and compared its results with those obtained from the traditional regression modeling and mixed-effects modeling approaches. We determined the best BP neural network structure with two hidden layers and five neurons in each layer, and logistic sigmoid transfer functions. Relative to the Mitscherlich height-diameter model that had the highest fitting precision among the six traditional height-diameter models evaluated, coefficient of determination (R2) of the neural network height-diameter model increased by 10.3%, root mean squares error (RMSE) and mean absolute error (MAE) decreased by 12% and 13.5%, respectively. The BP neural network height-diameter model also appeared more accurate than the mixed-effects height-diameter model. Our study proposes the method of determining the optimal numbers of hidden layers, neurons of each layer, and transfer functions in the BP neural network structure. This method can be useful for other modeling studies of similar or different types, such as tree crown modeling, height, and diameter increments modeling, and so on.
How to Formulate for Structure and Texture via Medium of Additive Manufacturing-A Review
Authors: Gholamipour-Shirazi Azarmidokht , Kamlow Michael-Alex , T. Norton Ian , Mills Tom
Published: April 2020

Additive manufacturing, which is also known as 3D printing, is an emerging and growing technology. It is providing significant innovations and improvements in many areas such as engineering, production, medicine, and more. 3D food printing is an area of great promise to provide an indulgence or entertaining experience, personalized food product, or specific nutritional needs. This paper reviews the additive manufacturing methods and materials in detail as well as their advantages and disadvantages. After a full discussion of 3D food printing, the reports on edible printed materials are briefly presented and discussed. In the end, the current and future outlook of additive manufacturing in the food industry is shown.
Pinot Blanc: Impact of the Winemaking Variables on the Evolution of the Phenolic, Volatile and Sensory Profiles
Authors: Dupas de Matos Amanda , Longo Edoardo , Chiotti Danila , Pedri Ulrich , Eisenstecken Daniela , Sanoll Christof , Robatscher Peter , Boselli Emanuele
Published: April 2020

The impact of two different winemaking practices on the chemical and sensory complexity of Pinot Blanc wines from South Tyrol (Italy), from grape pressing to the bottled wine stored for nine months, was studied. New chemical markers of Pinot blanc were identified: astilbin and trans-caftaric acid differentiated the wines according to the vinification; S-glutathionylcaftaric acid correlated with the temporal trends. Fluorescence analysis displayed strong time-evolution and differentiation of the two wines for gallocatechin and epigallocatechin, respectively. After nine months of storage in bottle, the control wine showed higher amounts of most ethyl esters, acetate esters and octanoic acid, whereas higher alcohols characterized instead the wine obtained with prefermentative cold maceration. The sensory panel found notes of apple and tropical fruit in the control wine and attributed a higher overall quality judgement to it, whereas the cold-macerated wine was described by olfactory intensity, spicy and pear attributes.
Descendants of Celia and Robert Newsom Speak
Authors: Wilson-Kleekamp Traci
Published: April 2020

This paper deploys narrative inquiry and analysis to capture the oral history of two families’ intergenerational memory of an African American woman named Celia who was hanged in 1855 for killing her owner Robert Newsom. It is the first scholarly investigation into the intergenerational memory of both black and white descendants of Robert Newsom, and the first to be conducted utilizing the theory of critical family history. Through the paradigm of Black Feminist Thought, the paper analyzes the power imbalances embedded in the narrative about family relations, especially those that conjure race, gender roles and class produced through oral history.
Genomic Instability in Fungal Plant Pathogens
Authors: Covo Shay
Published: April 2020

Fungi and fungal-like organisms (oomycetes) that cause diseases in plants have impacted human communities for centuries and probably from the dawn of agriculture. In modern agriculture, there is a constant race between new strategies to manage fungal plant pathogens and their ability to adapt. An important component in this race is fungal genetic diversity. Mechanisms such as sexual and parasexual recombination that contribute to the creation of novel allele combinations in fungal plant pathogens are briefly discussed in the first part of this review. Advances in genomics have enabled the investigation of chromosomal aberrations of agriculturally important fungal isolates at the nucleotide level. Some of these cases are summarized in the second part of this review; it is claimed that the effect of chromosomal aberrations on pathogenicity should be studied mechanistically. More data on the effect of gene copy number variations on phenotypes that are relevant to agriculture are especially needed. Genome rearrangements through translocations have shaped the genome of fungal plant pathogens by creating lineage-specific chromosome territories encoding for genes participating in plant diseases. Pathogenicity chromosomes are unique cases of such lineage-specific genetic elements, interestingly these chromosomes can be transferred horizontally and thus transforming a non-pathogenic strain to a pathogenic one. The third part of this review describes our attempts to reveal mutators in fungal plant pathogens by identifying fungi that lack important DNA repair genes or respond to DNA damage in an unconventional way. We found that a group of fungal plant pathogens lack conserved genes that are needed for an important Holliday junction resolution pathway. In addition, in Fusarium oxysporum, the rate-limiting step in dNTP production is not induced under DNA replication stress. This is very different from organisms from bacteria to humans. It remains to be seen if these mechanisms promote genetic instability in fungal plant pathogens.
Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of Aspergillus fumigatus
Authors: Dietl Anna-Maria , Binder Ulrike , Bauer Ingo , Shadkchan Yana , Osherov Nir , Haas Hubertus
Published: April 2020

Aspergillus fumigatus is an opportunistic human pathogen mainly infecting immunocompromised patients. The aim of this study was to characterize the role of arginine biosynthesis in virulence of A. fumigatus via genetic inactivation of two key arginine biosynthetic enzymes, the bifunctional acetylglutamate synthase/ornithine acetyltransferase (argJ/AFUA_5G08120) and the ornithine carbamoyltransferase (argB/AFUA_4G07190). Arginine biosynthesis is intimately linked to the biosynthesis of ornithine, a precursor for siderophore production that has previously been shown to be essential for virulence in A. fumigatus. ArgJ is of particular interest as it is the only arginine biosynthetic enzyme lacking mammalian homologs. Inactivation of either ArgJ or ArgB resulted in arginine auxotrophy. Lack of ArgJ, which is essential for mitochondrial ornithine biosynthesis, significantly decreased siderophore production during limited arginine supply with glutamine as nitrogen source, but not with arginine as sole nitrogen source. In contrast, siderophore production reached wild-type levels under both growth conditions in ArgB null strains. These data indicate that siderophore biosynthesis is mainly fueled by mitochondrial ornithine production during limited arginine availability, but by cytosolic ornithine production during high arginine availability via cytosolic arginine hydrolysis. Lack of ArgJ or ArgB attenuated virulence of A. fumigatus in the insect model Galleria mellonella and in murine models for invasive aspergillosis, indicating limited arginine availability in the investigated host niches.
‘Silent’ Dome Emplacement into a Wet Volcano: Observations from an Effusive Eruption at White Island (Whakaari), New Zealand in Late 2012
Authors: Jolly Arthur , Caudron Corentin , Girona Társilo , Christenson Bruce , Carniel Roberto
Published: April 2020

The 2012–2016 White Island (Whakaari) eruption sequence encompassed six small explosive events that included one steam driven and five explosive phreato-magmatic eruptions. More enigmatic, a dome was observed at the back of the vent and crater lake in November 2012. Its emplacement date could not be easily determined due to persistent steam from the evaporating crater lake and because of the very low levels of discrete volcanic earthquakes associated with its growth. During this period, seismicity also included persistent tremor with dominant frequencies in the 2–5 Hz range. Detailed assessment of the tremor reveals a very slow evolution of the spectral peaks from low to higher frequencies. These gliding spectral lines evolved over a three-month time period beginning in late September 2012 and persisting until early January 2013, when the tremor stabilised. As part of the dome emplacement episode, the crater lake progressively dried, leaving isolated pools which then promoted persistent mud/sulphur eruption activity starting in mid-January 2013. We interpret the emplacement of the dome as a non-explosive process where the hot, mostly degassed, magma intruded slowly through the hydrothermal system in late September 2012 and cooled in a relatively quiet state. The tremor evolution might reflect the slow contraction of subsurface resonant cavities, which increased the pitch of the peak resonant frequency through time. Alternatively, spectral evolution might reflect a ‘comb function’ due to clockwork beating of the slowly cooling dome, although direct evidence of clockwork beats is not seen in the waveform data. Finally, it might represent frothing of the hydrothermal system ahead of the slowly propagating magma.
Authenticity or Continuity in the Implementation of the UNESCO World Heritage Convention? Scrutinizing Statements of Outstanding Universal Value, 1978–2019
Authors: Khalaf Roha W.
Published: April 2020

Continuity is a key theme in conservation and one that appears in the text of the UNESCO World Heritage Convention, which requests States Parties to continue to protect, conserve and present properties situated on their territories (Article 26). Despite this fact, it is not put into effect. Instead, the Operational Guidelines for the implementation of this Convention retain authenticity as a benchmark for assessing cultural heritage. This article scrutinizes Statements of Outstanding Universal Value (SOUV) to prove that continuity is the evidence presented to justify inscription. It reveals that at least 263 properties were inscribed on the World Heritage List not because their values are truthfully and credibly expressed through a variety of attributes as per the Operational Guidelines (Paragraph 82), but because their values and attributes continue to exist. It also reveals that continuity is a recurring concept in other sections of the SOUV, and this holds true for natural properties. Indeed, continuity applies to both cultural and natural heritage, and to tangible and intangible attributes, but this is never admitted in the Operational Guidelines. In terms of future research directions, the article suggests exploring how change within properties affects judgements about authenticity and how guidance on impact assessment can be improved to better achieve the goal of compatible change, concluding that “an effective system of collective protection”, which is the raison-d’être of the Convention, is not one that aims at “conserving the authentic”, but one that aims at “managing continuity and compatible change” in an ever-evolving world.
The Effect of Maternal Depression on Infant Attachment: A Systematic Review
Authors: Śliwerski Andrzej , Kossakowska Karolina , Jarecka Karolina , Świtalska Julita , Bielawska-Batorowicz Eleonora
Published: April 2020

Aims and objectives: The aim of this systematic review was to summarize the key findings of empirical studies assessing the influence of maternal depression on child attachment security measured before 24 months after birth. Method: The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines. A literature search was conducted on the EBSCO (Academic Search Complete; Health Source: Nursing/Academic Edition; MEDLINE; PsycARTICLES) and PubMed databases, with infant attachment AND depression as search terms with Boolean operators. Study design or sample size did not affect inclusion. After screening, 29 of the 1510 unique publications originally identified were included in the review. Results: The studies reveal an equivocal association between maternal depression and child attachment security. Our findings indicate that depression had a significant influence on the attachment style almost only when diagnosed by structured interview: Depression measured by self-descriptive questionnaires was unrelated to attachment style. Furthermore, postpartum depression was found to be significant only when measured up to six months after childbirth. Conclusion: The relationship between maternal depression and infant attachment is both complex and dynamic, and the possible negative effects of depression might be compensated by maternal involvement in childcare. Therefore, further studies in this area should employ a reliable methodology for diagnosing depression and a suitable time point for measuring it; they should also adopt a multifactorial and prospective approach. It is important to note that breastfeeding/formula feeding was omitted as a factor in the majority of studies.
Does the Proximity of Meals to Bedtime Influence the Sleep of Young Adults? A Cross-Sectional Survey of University Students
Authors: Chung Nikola , Bin Yu Sun , Cistulli Peter A. , Chow Chin Moi
Published: April 2020

Avoiding food before bedtime is a widely accepted sleep hygiene practice, yet few studies have assessed meal timing as a risk factor for disrupted sleep. This study examined the relationship between evening meal timing and sleep quality in young adults. A total of N = 793 participants (26% male) aged between 18 and 29 years responded to an online survey, which captured sociodemographic information, lifestyle variables, and sleep characteristics. Meal timing was defined as meals more than 3 h before or within 3 h of bedtime. The outcomes were as follows: one or more nocturnal awakenings, sleep onset latency of >30 min, and sleep duration of ≤6 h. Logistic regression analyses showed that eating within 3 h of bedtime was positively associated with nocturnal awakening (OR = 1.61, 95% CI = 1.15–2.27) but not long sleep onset latency (1.24; 0.89–1.73) or short sleep duration (0.79; 0.49–1.26). The relationship remained significant after adjusting for potential confounders of ethnicity and body mass index (OR = 1.43, 95% CI = 1.00–2.04). Meal timing appears to be a modifiable risk factor for nocturnal awakenings and disrupted sleep. However, this is a preliminary cross-sectional study and highlights the need for additional research on the influence of the timing of food intake on sleep.
Identification of a New Heavy-Metal-Resistant Strain of Geobacillus stearothermophilus Isolated from a Hydrothermally Active Volcanic Area in Southern Italy
Authors: Puopolo Rosanna , Gallo Giovanni , Mormone Angela , Limauro Danila , Contursi Patrizia , Piochi Monica , Bartolucci Simonetta , Fiorentino Gabriella
Published: April 2020

Microorganisms thriving in hot springs and hydrothermally active volcanic areas are dynamically involved in heavy-metal biogeochemical cycles; they have developed peculiar resistance systems to cope with such metals which nowadays can be considered among the most permanent and toxic pollutants for humans and the environment. For this reason, their exploitation is functional to unravel mechanisms of toxic-metal detoxification and to address bioremediation of heavy-metal pollution with eco-sustainable approaches. In this work, we isolated a novel strain of the thermophilic bacterium Geobacillus stearothermophilus from the solfataric mud pool in Pisciarelli, a well-known hydrothermally active zone of the Campi Flegrei volcano located near Naples in Italy, and characterized it by ribotyping, 16S rRNA sequencing and mass spectrometry analyses. The minimal inhibitory concentration (MIC) toward several heavy-metal ions indicated that the novel G. stearothermophilus isolate is particularly resistant to some of them. Functional and morphological analyses suggest that it is endowed with metal resistance systems for arsenic and cadmium detoxification.
Proximity to Screening Site, Rurality, and Neighborhood Disadvantage: Treatment Status among Individuals with Sexually Transmitted Infections in Yakima County, Washington
Authors: Amiri Solmaz , Pham Christine D. , Amram Ofer , Alcover Karl C. , Oluwoye Oladunni , Bravo Lilian , Sixberry Melissa , McDonell Michael G. , Roll John M , Fresco Andre
Published: April 2020

Background: Early sexually transmitted infections (STIs) diagnosis facilitates prompt treatment initiation and contributes to reduced transmission. This study examined the extent to which contextual characteristics such as proximity to screening site, rurality, and neighborhood disadvantage along with demographic variables, may influence treatment seeking behavior among individuals with STIs (i.e., chlamydia, gonorrhea, and syphilis). Methods: Data on 16,075 diagnosed cases of STIs between 2007 and 2018 in Yakima County were obtained from the Washington State Department of Health Database Surveillance System. Multilevel models were applied to explore the associations between contextual and demographic characteristics and two outcomes: (a) not receiving treatment and (b) the number of days to receiving treatment. Results: Contextual risk factors for not receiving treatment or having increased number of days to treatment were living ≥10 miles from the screening site and living in micropolitan, small towns, or rural areas. Older age was a protective factor and being female was a risk for both outcomes. Conclusions: Healthcare providers and facilities should be made aware of demographic and contextual characteristics that can impact treatment seeking behavior among individuals with STIs, especially among youth, females, and rural residents.
Effects of Physical Exercise on Sexual Function and Quality of Sexual Life Related to Menopausal Symptoms in Peri- and Postmenopausal Women: A Systematic Review
Authors: Carcelén-Fraile María del Carmen , Aibar-Almazán Agustín , Martínez-Amat Antonio , Cruz-Díaz David , Díaz-Mohedo Esther , Redecillas-Peiró María Teresa , Hita-Contreras Fidel
Published: April 2020

During the menopausal period, sexual dysfunction is associated with the development or worsening of psychological conditions, causing deterioration in women’s mental health and quality of life. This systematic review aims to investigate the effects of different exercise programs on sexual function and quality of sexual life related to menopausal symptoms. With this purpose, a systematic literature search was conducted in PubMed, CINAHL, Scopus, Web of Science, and Cochrane Plus. A total of 1787 articles were identified in the initial search and 11 prospective studies (including 8 randomized controlled trials) were finally included. The most commonly recommended training programs are based on exercising pelvic floor muscles, as they seem to have the largest impact on sexual function. Mind–body disciplines also helped in managing menopausal symptoms. However, as far as the most traditional programs were concerned, aerobic exercises showed inconsistent results and resistance training did not seem to convey any benefits. Although positive effects have been found, evidence supporting physical exercise as a strategy to improve sexual function and quality of sexual life related to menopausal symptoms is limited, and further studies on this topic are needed.
Effects of a Psychological Management Program on Subjective Happiness, Anger Control Ability, and Gratitude among Late Adolescent Males in Korea
Authors: Hong Ju Eun , Kim Miok
Published: April 2020

This study aimed to develop an emotion management program for late adolescent males, and investigate the effect of the program. This study is an experimental study using a pretest-posttest control group design. It was conducted from 14 May to 21 December, 2018 at a male high school in Korea. It analyzed 52 participants (26 in the experimental group and 26 in the control group.) Regarding subjective happiness, there was a significant difference between groups (t = 3.409, p = 0.001). In anger control ability and gratitude, there was no significant difference between groups (t = 0.332, p = 0.740/ z = 0.528, p = 0.599). This program for emotion management, which is based on the broaden-and-build theory, can improve subjective happiness, anger control ability, and gratitude, by reinforcing appreciation skills and anger awareness and self-expression in male high school students.
Health Inequality as a Large-Scale Outcome of Complex Social Systems: Lessons for Action on the Sustainable Development Goals
Authors: Matheson Anna
Published: April 2020

Action on the Sustainable Development Goals (SDGs) needs to become real and impactful, taking a “whole systems” perspective on levers for systems change. This article reviews what we have learned over the past century about the large-scale outcome of health inequality, and what we know about the behaviour of complex social systems. This combined knowledge provides lessons on the nature of inequality and what effective action on our big goals, like the SDGs, might look like. It argues that economic theories and positivist social theories which have dominated the last 150 years have largely excluded the nature of human connections to each other, and the environment. This exclusion of intimacy has legitimatised arguments that only value-free economic processes matter for macro human systems, and only abstract measurement constitutes valuable social science. Theories of complex systems provide an alternative perspective. One where health inequality is viewed as emergent, and causes are systemic and compounding. Action therefore needs to be intensely local, with power relationships key to transformation. This requires conscious and difficult intervention on the intolerable accumulation of resources; improved reciprocity between social groups; and reversal of system flows, which at present ebb away from the local and those already disadvantaged.
Effects of Aerobic and Resistance Exercise on Myokines in High Fat Diet-Induced Middle-Aged Obese Rats
Authors: Ahn Nayoung , Kim Kijin
Published: April 2020

The objective of this study was to analyze the effects of aerobic and resistance exercise on myokines expression in the skeletal muscle of middle-aged rats with high fat diet-induced obesity, to investigate the feasibility of using exercise training to reduce inflammation. Male 50-week-old Sprague Dawley rats were divided into normal diet, normal diet + exercise, high fat diet, and high fat diet + exercise groups. After six weeks on a high fat diet to induce obesity, a 12-week exercise program was implemented, which combined aerobic exercise (treadmill running) and resistance exercise (ladder climbing) three times a week for 75 min per session. We analyzed the protein levels of interleukins (IL) 6, 7, and 8, C-X-C motif chemokine receptor 2, and vascular endothelial growth factor in skeletal muscles by western blotting. Body weight decreased significantly during the 12-week exercise program in the exercise groups compared to the non-exercise groups (p < 0.05). The levels of all myokines analyzed were significantly lower in the skeletal muscle of the high fat diet group compared to the normal diet group (p < 0.05). After completing the 12-week exercise program, IL-7, IL-8, C-X-C motif chemokine receptor 2, and vascular endothelial growth factor expressions were significantly higher in the high fat diet + exercise group compared to the high fat diet group (p < 0.05). However, while IL-6 expression was significantly lower in the high fat diet and high fat diet + exercise groups compared to the normal diet group (p < 0.05), it was not significantly affected by exercise. In conclusion, high fat diet-induced obesity resulted in decreased myokines in the skeletal muscles, but combined exercise training of aerobic and resistance exercise increased myokines secretion in the skeletal muscle of obese rats, and is thought to help reduce inflammation.
Improving the Named Entity Recognition of Chinese Electronic Medical Records by Combining Domain Dictionary and Rules
Authors: Chen Xianglong , Ouyang Chunping , Liu Yongbin , Bu Yi
Published: April 2020

Electronic medical records are an integral part of medical texts. Entity recognition of electronic medical records has triggered many studies that propose many entity extraction methods. In this paper, an entity extraction model is proposed to extract entities from Chinese Electronic Medical Records (CEMR). In the input layer of the model, we use word embedding and dictionary features embedding as input vectors, where word embedding consists of a character representation and a word representation. Then, the input vectors are fed to the bidirectional long short-term memory to capture contextual features. Finally, a conditional random field is employed to capture dependencies between neighboring tags. We performed experiments on body classification task, and the F1 values reached 90.65%. We also performed experiments on anatomic region recognition task, and the F1 values reached 93.89%. On both tasks, our model had higher performance than state-of-the-art models, such as Bi-LSTM-CRF, Bi-LSTM-Attention, and Vote. Through experiments, our model has a good effect when dealing with small frequency entities and unknown entities; with a small training dataset, our method showed 2–4% improvement on F1 value compared to the basic Bi-LSTM-CRF models. Additionally, on anatomic region recognition task, besides using our proposed entity extraction model, 12 rules we designed and domain dictionary were adopted. Then, in this task, the weighted F1 value of the three specific entities extraction reached 84.36%.
Performance and Biomass Characteristics of SBRs Treating High-Salinity Wastewater at Presence of Anionic Surfactants
Authors: Li Huiru , Wu Shaohua , Yang Chunping
Published: April 2020

Sodium dodecylbenzene sulfonate (SDBS) and sodium dodecyl sulfate (SDS), as two anionic surfactants, have diffused into environments such as surface water and ground water due to extensive and improper use. The effects on the removal performance and microbial community of sequencing batch reactors (SBRs) need to be investigated in the treatment of saline wastewater containing 20 g/L NaCl. The presence of SDS and SDBS could decrease the removal efficiencies of ammonia nitrogen and total phosphorus, and the effect of SDS was more significant. The effect of surfactants on the removal mainly occurred during the aeration phase. Adding SDS and SDBS can reduce the content of extracellular polymeric substances (EPS). In addition, SDS and SDBS also can reduce the inhibition of high salinity on sludge activity. A total of 16 s of rRNA sequencing analysis showed that the addition of surfactants reduced the diversity of microbial communities; besides, the relative abundance value of the dominant population Proteobacteria increased from 91.66% to 97.12% and 93.48% when SDS and SDBS were added into the system, respectively.
Coronavirus Diseases (COVID-19) Current Status and Future Perspectives: A Narrative Review
Authors: Di Gennaro Francesco , Pizzol Damiano , Marotta Claudia , Antunes Mario , Racalbuto Vincenzo , Veronese Nicola , Smith Lee
Published: April 2020

At the end of 2019 a novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing severe acute respiratory syndrome expanded globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus a global pandemic. We performed a narrative review to describe existing literature with regard to Corona Virus Disease 2019 (COVID-19) epidemiology, pathophysiology, diagnosis, management and future perspective. MEDLINE, EMBASE and Scopus databases were searched for relevant articles. Although only when the pandemic ends it will be possible to assess the full health, social and economic impact of this global disaster, this review represents a picture of the current state of the art. In particular, we focus on public health impact, pathophysiology and clinical manifestations, diagnosis, case management, emergency response and preparedness.
Symptom Perception and Influencing Factors in Chinese Patients with Heart Failure: A Preliminary Exploration
Authors: Luo Hong , Lindell Deborah F. , Jurgens Corrine Y. , Fan Yongsheng , Yu Liping
Published: April 2020

A growing body of evidence supports the fact that optimal health-related quality of life is largely dependent on patient competence in symptom perception. However, many studies have reported poor symptom perception in patients with heart failure. In China, there has been no previous research on assessing the symptom perception ability of patients with heart failure. This study aimed to describe how Chinese patients with heart failure perceive their symptoms, as well as to explore their influencing factors. A theory-based, descriptive, correlational cross-sectional design was used in this study. Data on symptom perception and factors related to symptom perception were collected via structured interviews and medical records. A convenience sample of 208 hospitalized patients was enrolled. The degree of symptom perception in this study was at a high level. The results showed that the level of depression, the New York Heart Association functional class, the left ventricular ejection fraction, and educational background were identified as independent factors of symptom perception in Chinese patients with heart failure. The degree of symptom perception of patients with heart failure was affected by personal, psychological, and physiological factors. Health policy and healthcare providers should pay more attention and deepen the understanding to Chinese patients with heart failure to provide better healthcare.
Full-Digital Workflow for Fabricating a Custom-Made Direct Metal Laser Sintering (DMLS) Mandibular Implant: A Case Report
Authors: Grecchi Francesco , Zecca Piero Antonio , Macchi Aldo , Mangano Alessandro , Riva Federica , Grecchi Emma , Mangano Carlo
Published: April 2020

Direct Laser Metal Sintering (DLMS) is an additive manufacturing (AM) technique that is capable of manufacturing metal parts according to a three-dimensional (3D) design made using computer-assisted-design (CAD) software, thanks to a powerful laser beam that melts selectively micro-powder layers, one on top of the other, until the desired object is generated. With DMLS, it is now possible to fabricate custom-made titanium implants for oral and maxillofacial applications. We present the case of a 67-year-old woman diagnosed with a squamous cell carcinoma of the mandible. The patient underwent subtotal mandibular resection; conventional reconstruction procedures failed to rehabilitate the function of the mandible. A prosthesis replacing the resected mandible was designed and fabricated using a digital workflow. The extensive bone defect was rehabilitated with a prosthesis replacing the mandibular bone and supporting a morse-taper dental prosthesis. The masticatory function was reestablished.
Testing the Usability of Digital Educational Games for Encouraging Smoking Cessation
Authors: Guo Jong-Long , Hsu Hsiao-Pei , Lin Mei-Hsun , Lin Cheng-Yu , Huang Chiu-Mieh
Published: April 2020

This study, using an observational design, assessed the effect of digital educational games on students’ intention to quit smoking. Specifically, a series of digital games were developed to encourage smoking cessation and enhance students’ engagement with the material. Three determinants of engagement were tested: perceived ease of use, perceived usefulness, and perceived satisfaction. Usability assessments were performed using a structured questionnaire and usability-testing software (Morae). Most students reported that the games were easy to use (73.3–93.3%), useful (60.0–83.3%) and satisfactory (66.7–70.0%). After using the games, approximately half (46.7–53.3%) reported that they intended to quit smoking. After controlling for gender and age, multiple regression analysis revealed that only perceived usefulness statistically significantly contributed to intention to quit (β = 2.38, p < 0.05). ‘Taiko Drumming’ showed the highest number of mouse clicks (67.23), and the lowest time between inputs (7.88 s). It also received the most positive feedback (17 marks). These findings show that integrating learners’ experiences into the development of learning material can improve learning effectiveness.
The Whole-of-Person Retention Improvement Framework: A Guide for Addressing Health Workforce Challenges in the Rural Context
Authors: Cosgrave Catherine
Published: April 2020

People living in rural places face unique challenges due to their geographic isolation and often experience poorer health outcomes compared to people living in major cities. The struggle to attract and retain an adequately-sized and skilled health workforce is a major contributing factor to these health inequities. Health professionals’ decisions to stay or leave a rural position are multifaceted involving personal, organisational, social and spatial aspects. While current rural health workforce frameworks/models recognise the multidimensional and interrelated influences on retention, they are often highly complex and do not easily support the development of strategic actions. An accessible evidence-informed framework that addresses the complexity but presents the evidence in a manner that is straightforward and supports the development of targeted evidence- and place-informed retention strategies is required. The ‘Whole-of-Person Retention Improvement Framework’ (WoP-RIF) has three domains: Workplace/Organisational, Role/Career and Community/Place. The necessary pre-conditions for improving retention through strengthening job and personal satisfaction levels are set out under each domain. The WoP-RIF offers a person-centred, holistic structure that encourages whole-of-community responses that address individual and workforce level needs. It is a significant response to, and resource for, addressing avoidable rural health workforce turnover that rural health services and communities can harness in-place.
The Impact of Non-optimum Ambient Temperature on Years of Life Lost: A Multi-county Observational Study in Hunan, China
Authors: Lv Ling-Shuang , Jin Dong-Hui , Ma Wen-Jun , Liu Tao , Xu Yi-Qing , Zhang Xing-E , Zhou Chun-Liang
Published: April 2020

The ambient temperature–health relationship is of growing interest as the climate changes. Previous studies have examined the association between ambient temperature and mortality or morbidity, however, there is little literature available on the ambient temperature effects on year of life lost (YLL). Thus, we aimed to quantify the YLL attributable to non-optimum ambient temperature. We obtained data from 1 January 2013 to 31 December 2017 of 70 counties in Hunan, China. In order to combine the effects of each county, we used YLL rate as a health outcome indicator. The YLL rate was equal to the total YLL divided by the population of each county, and multiplied by 100,000. We estimated the associations between ambient temperature and YLL with a distributed lag non-linear model (DNLM) in a single county, and then pooled them in a multivariate meta-regression. The daily mean YLL rates were 22.62 y/(p·100,000), 10.14 y/(p·100,000) and 2.33 y/(p·100,000) within the study period for non-accidental, cardiovascular, and respiratory disease death. Ambient temperature was responsible for advancing a substantial fraction of YLL, with attributable fractions of 10.73% (4.36–17.09%) and 16.44% (9.09–23.79%) for non-accidental and cardiovascular disease death, respectively. However, the ambient temperature effect was not significantly for respiratory disease death, corresponding to 5.47% (−2.65–13.60%). Most of the YLL burden was caused by a cold temperature than the optimum temperature, with an overall estimate of 10.27% (4.52–16.03%) and 15.94% (8.82–23.05%) for non-accidental and cardiovascular disease death, respectively. Cold and heat temperature-related YLLs were higher in the elderly and females than the young and males. Extreme cold temperature had an effect on all age groups in different kinds of disease-caused death. This study highlights that general preventative measures could be important for moderate temperatures, whereas quick and effective measures should be provided for extreme temperatures.
Erratum: Tang, G., et al. Politically Motivated Internet Addiction: Relationships among Online Information Exposure, Internet Addiction, FOMO, Psychological Well-being, and Radicalism in Massive Political Turbulence. Int. J. Environ. Res. Public Health 2020, 17, 633
Authors: Tang Gary , Hung Eva P. W. , Au-Yeung Ho-Kong Christopher , Yuen Samson
Published: April 2020

Due to an error during the editorial process, the article published was not the finalized one [...]
Mobile Measurement of PM2.5 Based on an Individual in Ulaanbaatar City
Authors: Ariunsaikhan Ariundelger , Chonokhuu Sonomdagva , Matsumi Yutaka
Published: April 2020

In the present study, we measured fine particulate matter (PM2.5) on the daily route of our study participant in order to determine her exposure and dose of PM2.5 in every microenvironment (ME). The measuring instrument, created by Nagoya University and Panasonic Corporation, Japan, was carried close to the breathing zone most of the time. Each data point was collected for 10–30 s or 2–6 cycles/min for 24 h from 1 October 2018 to 30 December 2018. Public transportation showed the highest level of PM2.5 compared with other MEs, including residence apartments, houses (ger district), the National University of Mongolia (NUM), food courts or restaurants, and other indoor locations. The personal daily average exposure to PM2.5 was 35 µg/m3 on 4 November 2018; on the other hand, this value was evaluated as the highest level of exposure compared to other measurement days. Interestingly, the study participant‘s exposure and dose of PM2.5 was lower than those stated in the World Health Organization (WHO) air quality guidelines, with 25 µg/m3 from 4:00 to 7:00.
Digital Health Interventions in Everyday Settings
Authors: De Cocker Katrien
Published: April 2020

Digitalisation, the use of digital technologies and platforms such as computers, websites, smartphones, and wearable devices, is everywhere in many ways [...]