bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Materials and Methods from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: April 2023

PDF - 100KB, Supplementary Materials and Methods
Supplementary Figure 3 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: April 2023

PDF - 151KB, KCNA1 knockdown and KCNA1 mutant S446E promote OIS escape.
Supplementary Figure 2 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: April 2023

PDF - 923KB, KCNA1 impacts RAF-induced hallmarks of OIS.
Supplementary Table S1 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: April 2023

Supplementary Table S1. Quantitation of HMGB1 secreted by cultured tumor cells, ex vivo macrophages and MDSC, in vivo grown tumors, and cultures of MDSC differentiated from bone marrow progenitor cells.
Supplementary Table 2 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 118K, Serum levels of LCN2 in breast cancer patients.
Supplementary Figure 4 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: April 2023

PDF file - 82K, Growth effects of NOTCH1 siRNA inhibition in HNSCC cells with wildtype NOTCH1 status. NOTCH1 was downregulated in UPCI-SCC090 (090, top, NOTCH1 wt) and SCC61 (bottom, NOTCH1 wt) by siRNA as described in methods. The effect of NOTCH1 downregulation on cell proliferation for these two cell lines is shown in the middle. The effect of siNOTCH1 on NOTCH1 expression (left) or expression of its targets (HES1 and HEY1, right) is also shown. The mRNA expression levels were calculated relative to GAPDH and were normalized to 1 in the control experiments with scrambled siRNA sequences. Experiments were performed in pentaplicates, mean plus-minus SEM were shown. *, p-value < 0.05.
Supplementary Methods from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 228K
Supplementary Figure 3 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: April 2023

PDF file - 108K, Validation of JAG1, JAG2, NOTCH1 and PSEN1 overexpression in TCGA HNSCC cohort. A, Overexpression of JAG1, JAG2 and NOTCH1 in tumors in comparison to that in normal tissues in the TCGA HNSCC cohort. B, Overexpression of JAG1 and PSEN1 in the tumors with increased copy number gains in comparison to that in the normal tissues as well as to that in the tumors without copy number gains in the TCGA HNSCC cohort. N, normal mucosa; T, HNSCC tumors; -, without JAG1 or PSEN1 copy number gain; +, with JAG1 or PSEN1 copy number gain. Dots, relative expression levels in different tissue samples. Boxes represent the interquartile range (25th-75th percentile) and horizontal lines inside the boxes indicate median. Whiskers indicate the minimum and maximum values. P value was calculated by using t test.
Supplementary Figure 8 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 344K, Endogenous HIC1 knockdown promotes cell migration and invasion in MCF-10A cells.
Supplementary Figure 7 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 132K, LCN2 does not affect PTEN activity.
Supplementary Figure 1 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: April 2023

PDF file, 7478K, Identification of NFATc1-positive tumor cells in human breast tumor specimens.
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: April 2023

Supplemental Table 1. Clinical parameters of human breast cancer cases.
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: April 2023

Supplemental Figure 3. Immunostaining for STAT3 phosphorylation in lungs from WT and Spp1-/- tumor bearing mice.
Supplementary Figure 5 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: April 2023

PDF file - 555K, Stainings of cytosolic DNA in Ara-C-treated BC2 cells and Yac-1 cells.
Supplementary Table 1 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 22KB, Primer and shRNA sequences.
Supplementary Figure 5 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 33KB, UTX or MLL4 knockdown did not have any obvious effect on total cellular levels of H3K27me3 and H3K4me3.
Supplementary Figure 2 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 33KB, UTX or MLL4 knockdown reduced expression levels of MMP-9, MMP-11, Six1, Cyclin A1, and CSPG4 genes in MDA-MB-468 cells.
Supplementary Methods, Figure Legend from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: April 2023

PDF file - 124K
Supplementary Figure 1 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: April 2023

PDF file - 94K, Relative CLPTM1L expression data from TCGA.
Supplementary Figure 4 from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: April 2023

PDF file - 107K, Cyclin D1 expression signature is induced in prostatospheres and induction of Wnt.
Supplementary Table 2 from Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Authors: Ryan Bríd M. , Robles Ana I. , McClary Andrew C. , Haznadar Majda , Bowman Elise D. , Pine Sharon R. , Brown Derek , Khan Mohammed , Shiraishi Kouya , Kohno Takashi , Okayama Hirokazu , Modali Ramakrishna , Yokota Jun , Harris Curtis C.
Published: April 2023

List of SNPs that failed primer design.
Supplementary Figure 4 from Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Authors: Ryan Bríd M. , Robles Ana I. , McClary Andrew C. , Haznadar Majda , Bowman Elise D. , Pine Sharon R. , Brown Derek , Khan Mohammed , Shiraishi Kouya , Kohno Takashi , Okayama Hirokazu , Modali Ramakrishna , Yokota Jun , Harris Curtis C.
Published: April 2023

CXCR2 isoform expression predicted by Emsembl.
Supplementary Figure S5 from β-Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells
Authors: Hong Yuan , Manoharan Indumathi , Suryawanshi Amol , Majumdar Tanmay , Angus-Hill Melinda L. , Koni Pandelakis A. , Manicassamy Balaji , Mellor Andrew L. , Munn David H. , Manicassamy Santhakumar
Published: April 2023

Supplementary Figure S5. Therapeutic effect of blocking the β-catenin pathway against established tumors.
Supplementary Figure S4 from β-Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells
Authors: Hong Yuan , Manoharan Indumathi , Suryawanshi Amol , Majumdar Tanmay , Angus-Hill Melinda L. , Koni Pandelakis A. , Manicassamy Balaji , Mellor Andrew L. , Munn David H. , Manicassamy Santhakumar
Published: April 2023

Supplementary Figure S4. Blocking β-catenin/TCF pathway enhances antitumor immunity against established EG7 and MO4 tumors.
Supplementary Figure Legend from Histone Deacetylase Inhibitors Repress Tumoral Expression of the Proinvasive Factor RUNX2
Authors: Sancisi Valentina , Gandolfi Greta , Ambrosetti Davide Carlo , Ciarrocchi Alessia
Published: April 2023

Supplementary Figure Legend. Legend for Supplementary Figure S1.
Supplementary Figure S3 from β-Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells
Authors: Hong Yuan , Manoharan Indumathi , Suryawanshi Amol , Majumdar Tanmay , Angus-Hill Melinda L. , Koni Pandelakis A. , Manicassamy Balaji , Mellor Andrew L. , Munn David H. , Manicassamy Santhakumar
Published: April 2023

Supplementary Figure S3. β-catenin signaling in DCs limits antitumor immunity by regulating the expression of co-inhibitory and co-stimulatory molecules.
Supplementary Table 2 from PI3K–mTORC2 but not PI3K–mTORC1 Regulates Transcription of HIF2A/EPAS1 and Vascularization in Neuroblastoma
Authors: Mohlin Sofie , Hamidian Arash , von Stedingk Kristoffer , Bridges Esther , Wigerup Caroline , Bexell Daniel , Påhlman Sven
Published: April 2023

Supplementary Table 2. Nucleotide sequences of primers used for qPCR reactions.
Supplementary Figure 2 from Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity
Authors: Bernardo M. Margarida , Kaplun Alexander , Dzinic Sijana H. , Li Xiaohua , Irish Jonathan , Mujagic Adelina , Jakupovic Benjamin , Back Jessica B. , Van Buren Eric , Han Xiang , Dean Ivory , Chen Yong Q. , Heath Elisabeth , Sakr Wael , Sheng Shijie
Published: April 2023

Supplementary Figure 2 - Maspin expression modulates HDAC enzymatic activity
Supplementary Figure 1 from Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity
Authors: Bernardo M. Margarida , Kaplun Alexander , Dzinic Sijana H. , Li Xiaohua , Irish Jonathan , Mujagic Adelina , Jakupovic Benjamin , Back Jessica B. , Van Buren Eric , Han Xiang , Dean Ivory , Chen Yong Q. , Heath Elisabeth , Sakr Wael , Sheng Shijie
Published: April 2023

Supplementary Figure 1 - Maspin expression in PTEN cells
Supplementary Figure S2 from Stem Cell Transplantation Reverses Chemotherapy-Induced Cognitive Dysfunction
Authors: Acharya Munjal M. , Martirosian Vahan , Chmielewski Nicole N. , Hanna Nevine , Tran Katherine K. , Liao Alicia C. , Christie Lori-Ann , Parihar Vipan K. , Limoli Charles L.
Published: April 2023

Morphometric data of pyramidal cell neurons.
Supplementary Figure S6 from CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ
Authors: Yan Hangyi H. , Jiang Jian , Pang Yanli , Achyut B.R. , Lizardo Michael , Liang Xinhua , Hunter Kent , Khanna Chand , Hollander Christine , Yang Li
Published: April 2023

Fold increase in myeloid cell subsets in the lungs.
Supplementary Table 4 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

The expression levels of stem cell markers.
Dataset S2 from Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications
Authors: Vasudevan Divya , Hickok Jason R. , Bovee Rhea C. , Pham Vy , Mantell Lin L. , Bahroos Neil , Kanabar Pinal , Cao Xing-Jun , Maienschein-Cline Mark , Garcia Benjamin A. , Thomas Douglas D.
Published: April 2023

GO terms associated with upregulated genes bearing new ÃƒÂ¢Ã‹â€ Ã¢â€žÂ¢NO-induced H3K9ac peaks around promoter regions
Supplementary Figure 7 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Gene expression profiles of breast cancer cells grown as monolayer or sphere-forming cells.
Table S2 from Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
Authors: Wu Min-Zu , Chen Su-Feng , Nieh Shin , Benner Christopher , Ger Luo-Ping , Jan Chia-Ing , Ma Li , Chen Chien-Hung , Hishida Tomoaki , Chang Hong-Tai , Lin Yaoh-Shiang , Montserrat Nuria , Gascon Pedro , Sancho-Martinez Ignacio , Izpisua Belmonte Juan Carlos
Published: April 2023

Table S2: Sequence of the oligonucleotides for shRNA, real-time PCR, and ChIP assay.
Supplementary manuscript from NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth
Authors: Satoh Hironori , Moriguchi Takashi , Saigusa Daisuke , Baird Liam , Yu Lei , Rokutan Hirofumi , Igarashi Keiko , Ebina Masahito , Shibata Tatsuhiro , Yamamoto Masayuki
Published: April 2023

Supplementary Materials and Methods and Supplementary Figure Legends.
Supplementary Figure 5 from Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma
Authors: Lin De-Chen , Xu Liang , Chen Ye , Yan Haiyan , Hazawa Masaharu , Doan Ngan , Said Jonathan W. , Ding Ling-Wen , Liu Li-Zhen , Yang Henry , Yu Shizhu , Kahn Michael , Yin Dong , Koeffler H. Phillip
Published: April 2023

Supplementary Figure 5. Dual inhibition of glioma cells with combinational use of MK2206 and ICG001.
Supplementary Tables 1 - 15 from IKKβ Enforces a LIN28B/TCF7L2 Positive Feedback Loop That Promotes Cancer Cell Stemness and Metastasis
Authors: Chen Chong , Cao Fengqi , Bai Lipeng , Liu Yan , Xie Junling , Wang Wei , Si Qin , Yang Jian , Chang Antao , Liu Dong , Liu Dachuan , Chuang Tsung-Hsien , Xiang Rong , Luo Yunping
Published: April 2023

Supplementary Table 1. Clinicopathological characteristics of patients from breast cancer tissue array. Supplementary Table 2. Clinicopathological characteristics of patients from breast cancer tissue array (with survival datas). Supplementary Table 3. Clinicopathological characteristics of patients from lung cancer tissue array (with survival datas). Supplementary Table 4. The numbers of normal or staged breast cancer tissues based on LIN28B expression. Supplementary Table 5. The correlation of LIN28B with ALDH1 in breast cancer tissues. Supplementary Table 6. The correlation of LIN28B with ALDH1 in breast cancer tissues. Supplementary Table 7. The correlation of LIN28B with TCF7L2 in breast cancer tissues. Supplementary Table 8. Tumor incidence of ALDH-/ ALDH+ MDA-MB-231 cells in limiting dilutions. Supplementary Table 9. Tumorsphere formation of shNC/ shLIN28B MDA-MB-231 cells in limiting dilutions. Supplementary Table 10. Tumorsphere formation of shNC/ shLIN28B H1299 cells in limiting dilutions. Supplementary Table 11. Tumorsphere formation of MDA-MB-231 cells treated with DMSO/IMD-0354/Taxol/IMD-0354+Taxol in limiting dilutions. Supplementary Table 12. Tumor incidence of shNC/ shLIN28B H1299 cells in limiting dilutions. Supplementary Table 13. Primer sequences. Supplementary Table 14. The small interfering RNAs (siRNAs). Supplementary Table 15. Antibody list.
Supplementary Figure S2 from The CUL4B/AKT/β-Catenin Axis Restricts the Accumulation of Myeloid-Derived Suppressor Cells to Prohibit the Establishment of a Tumor-Permissive Microenvironment
Authors: Qian Yanyan , Yuan Jupeng , Hu Huili , Yang Qifeng , Li Jisheng , Zhang Shuqian , Jiang Baichun , Shao Changshun , Gong Yaoqin
Published: April 2023

Supplementary Figure S2. Activation and immune effect of CD8+ T cells and NK cells.
Supplemental Materials and Methods from VEGF-A Expression Correlates with TP53 Mutations in Non–Small Cell Lung Cancer: Implications for Antiangiogenesis Therapy
Authors: Schwaederlé Maria , Lazar Vladimir , Validire Pierre , Hansson Johan , Lacroix Ludovic , Soria Jean-Charles , Pawitan Yudi , Kurzrock Razelle
Published: April 2023

Supplemental Materials and Methods. Description of additional methods and procedures used in the study.
Supplementary Table S1 from Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer
Authors: Albino Domenico , Civenni Gianluca , Dallavalle Cecilia , Roos Martina , Jahns Hartmut , Curti Laura , Rossi Simona , Pinton Sandra , D'Ambrosio Gioacchino , Sessa Fausto , Hall Jonathan , Catapano Carlo V. , Carbone Giuseppina M.
Published: April 2023

Primer sets for qRT-PCR and ChIP experiments.
Supplemental Figures from Eradication of Acute Myeloid Leukemia with FLT3 Ligand–Targeted miR-150 Nanoparticles
Authors: Jiang Xi , Bugno Jason , Hu Chao , Yang Yang , Herold Tobias , Qi Jun , Chen Ping , Gurbuxani Sandeep , Arnovitz Stephen , Strong Jennifer , Ferchen Kyle , Ulrich Bryan , Weng Hengyou , Wang Yungui , Huang Hao , Li Shenglai , Neilly Mary Beth , Larson Richard A. , Le Beau Michelle M. , Bohlander Stefan K. , Jin Jie , Li Zejuan , Bradner James E. , Hong Seungpyo , Chen Jianjun
Published: April 2023

Supplemental Figure 1. Construction of G7-FLT3L dendrimers and their uptake ratio in AML cells. Supplemental Figure 2. G7 PAMAM dendrimers efficiently complex small, single stranded oligonucleotides. Supplemental Figure 3. G7-FLT3L-miR-150 nanoparticles repressed expression of direct or indirect target genes of miR-150 in vitro. Supplemental Figure 4. The specific targeting and inhibitory effect of G7-Flt3L-miR-150 nanoparticles to FLT3-overexpressing AML cells in vitro. Supplemental Figure 5. In vivo uptake and function of G7-Flt3L-miR-150 nanoparticles. Supplemental Figure 6. Analysis of the potential influence of the nanoparticles on hematopoietic system in normal mice.
Supplementary Methods and References from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figure S1 from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: April 2023

Kaplan-Meier survival plots for mice receiving 0 Gy or 5.4 Gy TBI.
Supplementary Figure 7 from Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition
Authors: Herkert Barbara , Kauffmann Audrey , Mollé Sandra , Schnell Christian , Ferrat Thomas , Voshol Hans , Juengert Janina , Erasimus Hélène , Marszalek Grégory , Kazic-Legueux Malika , Billy Eric , Ruddy David , Stump Mark , Guthy Daniel , Ristov Mitko , Calkins Keith , Maira Sauveur-Michel , Sellers William R. , Hofmann Francesco , Hall Michael N. , Brachmann Saskia M.
Published: April 2023

Concomitant inhibition of PI3Kβ, IGF1R and MAPK signaling are leading to induction of cell death. A) Effects of treatment with the indicated inhibitors as single-agents in RVH-421 were evaluated by immunoblotting using phospho-specific or total target protein antibodies. B) Fractions of living (A-/PI-), necrotic (A-/PI+), early (A+/PI-) and late (A+/PI+) apoptotic cells was measured upon treatment of A101D and C32 with the indicated compounds for 72h. Data are represented as mean ({plus minus}SD) of triplicates. PI3Kβi=rac-KIN-193, PI3Kαi=BYL719, IGF1Ri=AEW541, panPI3Ki=GDC0941, BRAFi=LGX818, MEKi=MEK162
Supplementary Figure 3 from Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition
Authors: Herkert Barbara , Kauffmann Audrey , Mollé Sandra , Schnell Christian , Ferrat Thomas , Voshol Hans , Juengert Janina , Erasimus Hélène , Marszalek Grégory , Kazic-Legueux Malika , Billy Eric , Ruddy David , Stump Mark , Guthy Daniel , Ristov Mitko , Calkins Keith , Maira Sauveur-Michel , Sellers William R. , Hofmann Francesco , Hall Michael N. , Brachmann Saskia M.
Published: April 2023

Despite major dependence of PTENLOF/BRAFMUT melanoma cell lines on PI3Kβ, PI3Kαi synergizes with PI3Kβi to inhibit downstream signaling upon long-term treatment. A) +B) Effects of treatment with the indicated inhibitors as single-agents or in combination for 2h (A) and 72h (B) on PI3K signaling was determined by immunoblotting in PTENLOF/BRAFMUT melanoma cell lines. PI3Kβi=rac-KIN-193, PI3Kαi=BYL719, PI3Kδi=CAL101
Supplementary Table 2 from PDLIM1 Stabilizes the E-Cadherin/β-Catenin Complex to Prevent Epithelial–Mesenchymal Transition and Metastatic Potential of Colorectal Cancer Cells
Authors: Chen Hai-Ning , Yuan Kefei , Xie Na , Wang Kui , Huang Zhao , Chen Yan , Dou Qianhui , Wu Min , Nice Edouard C. , Zhou Zong-Guang , Huang Canhua
Published: April 2023

Supplementary Table 2: Correlation between clinicopathologic features in CRC patients and the expression of PDLIM1, E-cadherin, membrane β-catenin, respectively.
Supplementary Figure 2 from PDLIM1 Stabilizes the E-Cadherin/β-Catenin Complex to Prevent Epithelial–Mesenchymal Transition and Metastatic Potential of Colorectal Cancer Cells
Authors: Chen Hai-Ning , Yuan Kefei , Xie Na , Wang Kui , Huang Zhao , Chen Yan , Dou Qianhui , Wu Min , Nice Edouard C. , Zhou Zong-Guang , Huang Canhua
Published: April 2023

Supplementary Figure 2: Both E-cadherin and membrane β-catenin are downregulated in CRC.
Supplementary Table 1 from Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas
Authors: Tang Xiaohu , Wu Jianli , Ding Chien-Kuang , Lu Min , Keenan Melissa M. , Lin Chao-Chieh , Lin Chih-An , Wang Charles C. , George Daniel , Hsu David S. , Chi Jen-Tsan
Published: April 2023

Supplementary Table 1. GSEA analysis report on gene profile of RCC4 VHL-deficient and -restored cells
Supplementary Materials and Methods and Supplementary Figures 1 through 7 from Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas
Authors: Tang Xiaohu , Wu Jianli , Ding Chien-Kuang , Lu Min , Keenan Melissa M. , Lin Chao-Chieh , Lin Chih-An , Wang Charles C. , George Daniel , Hsu David S. , Chi Jen-Tsan
Published: April 2023

Supplementary materials and methods. Figure S1: VHL renders renal cancer cell resistant to cystine deprivation-induced cell death. Figure S2: Cystine deprivation induces a programmed necrosis in VHL-deficient renal cancer cells. Figure S3: VHL represses TNFalpha expression to protect from Cystine-deprived necrosis. Figure S4: Metabolomic and transcriptional response to cystine deprivation. Figure S5: Activation of Src and p38 kinases is required for cystine-deprived necrosis. Figure S6: Mutual amplification between the Src-p38-Noxa and TNF-RIP1/3-MLKL pathways. Figure S7: Low doses of erastin share a similar mechanism as cystine deprivation to trigger programmed necrosis in ccRCC.
Table S6 from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: April 2023

Genes significantly induced in Be(2)-C or IMR5-75 upon treatment with DAC, EPZ-6438 or a combination of both drugs (adjusted p-value<0.05, sorted by log2 fold change)
Supplemental Methods from EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer
Authors: Amato Katherine R. , Wang Shan , Tan Li , Hastings Andrew K. , Song Wenqiang , Lovly Christine M. , Meador Catherine B. , Ye Fei , Lu Pengcheng , Balko Justin M. , Colvin Daniel C. , Cates Justin M. , Pao William , Gray Nathanael S. , Chen Jin
Published: April 2023

Description of additional methods and procedures used in the study.
Supplementary figure 2 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: April 2023

Metabolic profiles of breast cancer cells in response to estrogen treatment
Supplementary Table 4 from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: April 2023

Supplementary Table S4. Histology scores for CD4Stat3-/- and WT (CD4Stat3+/+) C57BL/6 mice colonized 7 days with ETBF.
Supplementary Table 3 from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: April 2023

Supplementary Table S3. Demographic and pathologic characteristics of the Malaysian CRC patients.
Supplementary tables from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: April 2023

This file contains 4 supplementary tables: Table S1 provides the expression values of the indicated genes (RMA) in BETi sensitive and insensitive cell lines; Table S2 shows the enrichment of subtypes of cell lines following selection with the indicated criteria; Table S3 shows SNP analysis of parental and BETi tolerant A375 cells; Table S4 shows SNP analysis of parental and BETi tolerant NOMO-1 cells.
Supplementary figure legends from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: April 2023

This file contains the legends for the six supplementary figures.
Figure S6 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: April 2023

miR-214 and miR-148b coordinate lung metastasis formation in an opposite manner
Supplementary Table 5 from Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Archer Michael A. , Yeap Beow Y. , Dao Nhien , Sciaranghella Daniele , Sideris Antonios C. , Zheng Yifan , Holman Alexander G. , Wang Yaoyu E. , Dal Cin Paola S. , Fletcher Jonathan A. , Rubio Renee , Croft Larry , Quackenbush John , Sugarbaker Peter E. , Munir Kiara J. , Battilana Jesse R. , Gustafson Corinne E. , Chirieac Lucian R. , Ching Soo Meng , Wong James , Tay Liang Chung , Rudd Stephen , Hercus Robert , Sugarbaker David J. , Richards William G. , Bueno Raphael
Published: April 2023

List of SNVs identified in the analyzed genes
Figure S1 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: April 2023

Analysis of miR-214 and miR-148b sponge efficacy
Supplementary Figure Legend from Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations
Authors: Riquelme Erick , Behrens Carmen , Lin Heather Y. , Simon George , Papadimitrakopoulou Vassiliki , Izzo Julie , Moran Cesar , Kalhor Neda , Lee J. Jack , Minna John D. , Wistuba Ignacio I.
Published: April 2023

1.EZH2 and MEK-ERK and PI3K/AKT signaling pathway expression in lung adenocarcinoma and HBEC cell lines and 2. Sensitivity in vitro to AZD6244 and MK2206 in combination with selective EZH2 inhibitor GSK343, EPZ6438 and GSK126 in NSCLC cells.
Supplementary Figure S2 from Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models
Authors: O'Connor James P.B. , Boult Jessica K.R. , Jamin Yann , Babur Muhammad , Finegan Katherine G. , Williams Kaye J. , Little Ross A. , Jackson Alan , Parker Geoff J.M. , Reynolds Andrew R. , Waterton John C. , Robinson Simon P.
Published: April 2023

Validation of R1 measurement accuracy
Supplementary Figure S1 from Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models
Authors: O'Connor James P.B. , Boult Jessica K.R. , Jamin Yann , Babur Muhammad , Finegan Katherine G. , Williams Kaye J. , Little Ross A. , Jackson Alan , Parker Geoff J.M. , Reynolds Andrew R. , Waterton John C. , Robinson Simon P.
Published: April 2023

Schematic representation of MRI protocols
Supplementary Tables 1 through 3 from Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas
Authors: Bouillez Audrey , Rajabi Hasan , Pitroda Sean , Jin Caining , Alam Maroof , Kharbanda Akriti , Tagde Ashujit , Wong Kwok-Kin , Kufe Donald
Published: April 2023

qPCR Primers (S1); Promoter ChIP qPCR Primers (S2); Combination Indices (S3).
Supplementary Table S3 from Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications
Authors: Popova Tatiana , Manié Elodie , Boeva Valentina , Battistella Aude , Goundiam Oumou , Smith Nicholas K. , Mueller Christopher R. , Raynal Virginie , Mariani Odette , Sastre-Garau Xavier , Stern Marc-Henri
Published: April 2023

Summary for structural alterations detected by paired-end WGS for 25 TCGA ovarian tumors
Supplementary Methods from Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications
Authors: Popova Tatiana , Manié Elodie , Boeva Valentina , Battistella Aude , Goundiam Oumou , Smith Nicholas K. , Mueller Christopher R. , Raynal Virginie , Mariani Odette , Sastre-Garau Xavier , Stern Marc-Henri
Published: April 2023

Supplementary Materials and Methods and References
Supplementary Figure S7 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

siRNA-Mediated Knockdown of KRAS or Overexpression of KRASG12V Has No Effect on FAK mRNA Levels in NSCLC Lines.
Supplementary Figure S4 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

miR-1298 promotes apotosis in KRASmut NSCLC cell line.
Supplementary Figure S2 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

Mutation Background of Non-Small Cell Lung Cancer Lines.
Supplementary Figure S3 from PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling
Authors: Hein Ashley L. , Seshacharyulu Parthasarathy , Rachagani Satyanarayana , Sheinin Yuri M. , Ouellette Michel M. , Ponnusamy Moorthy P. , Mumby Marc C. , Batra Surinder K. , Yan Ying
Published: April 2023

Effect of PR55Î± expression on mobility of pancreatic cancer cells.
Supplementary Figure Legends from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

Legend for Supplementary Figures S1-S8
Supplementary Figure S3 from Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation
Authors: Prabhu Varun V. , Hong Bo , Allen Joshua E. , Zhang Shengliang , Lulla Amriti R. , Dicker David T. , El-Deiry Wafik S.
Published: April 2023

Prodigiosin is non-toxic at the therapeutic dose in vivo.
Supplementary Figure Legends from EGF816 Exerts Anticancer Effects in Non–Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor
Authors: Jia Yong , Juarez Jose , Li Jie , Manuia Mari , Niederst Matthew J. , Tompkins Celin , Timple Noelito , Vaillancourt Mei-Ting , Pferdekamper AnneMarie Culazzo , Lockerman Elizabeth L. , Li Chun , Anderson Jennifer , Costa Carlotta , Liao Debbie , Murphy Eric , DiDonato Michael , Bursulaya Badry , Lelais Gerald , Barretina Jordi , McNeill Matthew , Epple Robert , Marsilje Thomas H. , Pathan Nuzhat , Engelman Jeffrey A. , Michellys Pierre-Yves , McNamara Peter , Harris Jennifer , Bender Steven , Kasibhatla Shailaja
Published: April 2023

This file contains the supplementary figure legends. Figure S1 shows the chemical structure of EGF816 and its binding to EGFR T790M mutant. Figure S2 shows the tolerability of EGF816 in the in vivo xenograft models. Figure S3 shows the in vivo PK and PD after a single dose of EGF816. Figure S4 shows the selectivity profile of EGF816 in the kinome tree. Figure S5 shows the morphology of EGF816 resistance clones.
Supplementary Figure Legends from PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer
Authors: Nagarsheth Nisha , Peng Dongjun , Kryczek Ilona , Wu Ke , Li Wei , Zhao Ende , Zhao Lili , Wei Shuang , Frankel Timothy , Vatan Linda , Szeliga Wojciech , Dou Yali , Owens Scott , Marquez Victor , Tao Kaixiong , Huang Emina , Wang Guobin , Zou Weiping
Published: April 2023

This file contains the legends for the supplementary figures.
Supplementary Figure 5 from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Fig. S5 CSC markers and self-renewal of GFPhigh SW480 cells.
Supplementary Table S2 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

Correlations of SMAD2 phosphorylation to clinico-pathological parameters and molecular markers.
Supplemental Figures from SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth
Authors: Park Seong-Hoon , Ozden Ozkan , Liu Guoxiang , Song Ha Yong , Zhu Yueming , Yan Yufan , Zou Xianghui , Kang Hong-Jun , Jiang Haiyan , Principe Daniel R. , Cha Yong-Il , Roh Meejeon , Vassilopoulos Athanassios , Gius David
Published: April 2023

Supplemental Figure S1. PKM2 is acetylated by PCAF and Tip60. Supplemental Figure S2. SIRT2-knockdown stable MCF7, MDA-MB-231, and HeLa cell lines showed decreased PK activity and increased glycolysis rate. Supplemental Figure S3. LC-Ms/Ms analysis to detect potentially reversible acetylation sites of PKM2 peptide. Supplemental Figure S4. Sirt2-/--MMT cell growth was inhibited by SIRT2 and PKM2-deacetylation mimic mutants. Supplemental Figure S5. PKM2 deacetylation mimic mutants (K62R and K305R) increased PKM2 tetramer formation.
Supplementary Materials and Methods, Supplementary Figure Legends, and Supplementary Tables 1 through 5 from SSBP1 Suppresses TGFβ-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling
Authors: Jiang Hong-Lin , Sun He-Fen , Gao Shui-Ping , Li Liang-Dong , Huang Sheng , Hu Xin , Liu Sheng , Wu Jiong , Shao Zhi-Ming , Jin Wei
Published: April 2023

Supplementary Materials and Methods, Supplementary Figure Legends, Supplementary Table S1 Alteration of SSBP1 protein expression levels in relation to clinicopathological characteristics in breast cancer patients. Supplementary Table S2 Antibodies used in this study. Supplementary Table S3 Primers for plasmid construction. Supplementary Table S4 Primers for ChIP. Supplementary Table S5 iTRAQ: Dysregulated proteins with gene symbol.
Supplementary Figure S3 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

Viability of MCF7 with TGFBR2-specific knockdown.
Supplementary Figure S2 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

SMAD2 phosphorylation (pSMAD2) and its associations to survival outcome in invasive breast cancer.
Supplementary Figure S1 from SSBP1 Suppresses TGFβ-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling
Authors: Jiang Hong-Lin , Sun He-Fen , Gao Shui-Ping , Li Liang-Dong , Huang Sheng , Hu Xin , Liu Sheng , Wu Jiong , Shao Zhi-Ming , Jin Wei
Published: April 2023

(A) Representative HE staining images of nude mouse lungs six weeks after the tail vein injection of MDA-MB-231 and MDA-MB-231Bo cells. (B) The SSBP1 peptide sequence was detected by iTRAQ labeling. (C) The fold change ratio of breast cancer cell lines (MDA-MB-231, MDA-MB-231HM and MDA-MB-231Bo) based on quantitative proteomic analysis (D) Western blotting for SSBP1 in MDA-MB-231 parent and MDA-MB-231HM, MDA-MB-231Bo subclone confirming expression levels seen in proteomic analyses. (E) Log2 expression levels for mitochondrial proteins from the MDA-MB-231 parent and MDA-MB-231-derivated cell lines.
Supplementary Figure 4 from NFAT1 Directly Regulates IL8 and MMP3 to Promote Melanoma Tumor Growth and Metastasis
Authors: Shoshan Einav , Braeuer Russell R. , Kamiya Takafumi , Mobley Aaron K. , Huang Li , Vasquez Mayra E. , Velazquez-Torres Guermarie , Chakravarti Nitin , Ivan Cristina , Prieto Victor , Villares Gabriel J. , Bar-Eli Menashe
Published: April 2023

Schematic presentation of the IL-8 and MMP-3 promoters for NFAT1 binding sites
Supplementary Table S2 from Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Authors: Jin Ye , Tang Senwei , Li Weilin , Ng Siew Chien , Chan Michael W.Y. , Sung Joseph J.Y. , Yu Jun
Published: April 2023

Virulence genes present in different types of E. coli isolates
Supplementary Figures 1 though 6 from Balancing Protein Stability and Activity in Cancer: A New Approach for Identifying Driver Mutations Affecting CBL Ubiquitin Ligase Activation
Authors: Li Minghui , Kales Stephen C. , Ma Ke , Shoemaker Benjamin A. , Crespo-Barreto Juan , Cangelosi Andrew L. , Lipkowitz Stanley , Panchenko Anna R.
Published: April 2023

Fig. S1. The distribution of unfolding and binding free energy changes for Single, Recurrent and Random class mutations for all states in CBL activation cycle. Fig.S2. The distribution of local RMSD of mutant structures for Single, Recurrent and Random class mutations for CBL-E2-S and pCBL-E2-S states. Fig. S3. Mean values and standard errors of local RMSD of mutant structures for different classes of mutations for CBL-E2-S and pCBL-E2-S states, respectively. Fig. S4. The number of "Single" and "Recurrent" mutations located on CBL-E2 interface, non-interface and interior regions in inactive CBL-E2-S and active pCBL-E2-S structures. Fig. S5. Structures of wild type and K382E mutant for all states. Fig. S6. EGFR ubiquitination by Cbl mutants that retain wild-type activity in A549 and Hela cells.
CAN-15-1348R-Supplementary Figure-S3 from Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression
Authors: Mittapalli Venugopal R. , Madl Josef , Löffek Stefanie , Kiritsi Dimitra , Kern Johannes S. , Römer Winfried , Nyström Alexander , Bruckner-Tuderman Leena
Published: April 2023

Images of Western blot analysis
CAN-15-1348R-Supplementary Figure-S2 from Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression
Authors: Mittapalli Venugopal R. , Madl Josef , Löffek Stefanie , Kiritsi Dimitra , Kern Johannes S. , Römer Winfried , Nyström Alexander , Bruckner-Tuderman Leena
Published: April 2023

Immunofluorescence stainings of mouse lung
Supplementary Table S3 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Summary of Validation Studies.
Supplementary Figure Legends from HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc
Authors: Li Yinghui , Wang Zhen , Shi Hui , Li Hang , Li Leilei , Fang Runping , Cai Xiaoli , Liu Bowen , Zhang Xiaodong , Ye Lihong
Published: April 2023

Legends for Supplementary Figures S1-S6.
Supplementary Figure S8 from Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-κB Signaling Pathway
Authors: Ohtsu Naoki , Nakatani Yuka , Yamashita Daisuke , Ohue Shiro , Ohnishi Takanori , Kondo Toru
Published: April 2023

Relationship between relb expression and the prognosis.
Supplementary Figure S4 from Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-κB Signaling Pathway
Authors: Ohtsu Naoki , Nakatani Yuka , Yamashita Daisuke , Ohue Shiro , Ohnishi Takanori , Kondo Toru
Published: April 2023

Self-renewal activity of eva1- and eva1sh-expressing hGICs.
Supplementary Figure Legends from Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-κB Signaling Pathway
Authors: Ohtsu Naoki , Nakatani Yuka , Yamashita Daisuke , Ohue Shiro , Ohnishi Takanori , Kondo Toru
Published: April 2023

Legends for Supplementary Figures S1-S9.
Supplementary methods from Rapalogs Efficacy Relies on the Modulation of Antitumor T-cell Immunity
Authors: Beziaud Laurent , Mansi Laura , Ravel Patrice , Marie-Joseph Elodie Lauret , Laheurte Caroline , Rangan Laurie , Bonnefoy Francis , Pallandre Jean-René , Boullerot Laura , Gamonet Clémentine , Vrecko Sindy , Queiroz Lise , Maurina Tristan , Mouillet Guillaume , Hon Thierry Nguyen Tan , Curtit Elsa , Royer Bernard , Gaugler Béatrice , Bayry Jagadeesh , Tartour Eric , Thiery-Vuillemin Antoine , Pivot Xavier , Borg Christophe , Godet Yann , Adotévi Olivier
Published: April 2023

This file contains the supplementary material and methods
Supplementary figure legends from Rapalogs Efficacy Relies on the Modulation of Antitumor T-cell Immunity
Authors: Beziaud Laurent , Mansi Laura , Ravel Patrice , Marie-Joseph Elodie Lauret , Laheurte Caroline , Rangan Laurie , Bonnefoy Francis , Pallandre Jean-René , Boullerot Laura , Gamonet Clémentine , Vrecko Sindy , Queiroz Lise , Maurina Tristan , Mouillet Guillaume , Hon Thierry Nguyen Tan , Curtit Elsa , Royer Bernard , Gaugler Béatrice , Bayry Jagadeesh , Tartour Eric , Thiery-Vuillemin Antoine , Pivot Xavier , Borg Christophe , Godet Yann , Adotévi Olivier
Published: April 2023

This file contains the legends for the supplementary figures