bluuebunny/crossref_metadata_2025 huggingface dataset:
A seca no território de identidade Bacia do Jacuípe entre 2010 e 2012 e suas causas e consequências no espaço geográfico
Authors: Santos Géssica de Oliveira
Published: April 2022

É constatado no Território de Identidade Bacia do Jacuípe a caracterização do fenômeno climático da seca, sendo este um fator natural. Com isso, verifica-se prolongadas estiagens que atinge a população e o principal meio de subsistência que é a agricultura, criação de animais que contribui para a economia.
Plasmonic band and defect mode of a one-dimensional graphene lattice
Authors: Zhou Yun-Cheng , Zeng Xiaodong , Din Rafi Ud , Ge Guo-Qin , Zubairy Muhammad Suhail
Published: April 2022

Photonic crystals based on graphene plasmons are highly tunable and can accurately control photonic transmission at nanoscale. In this work, the transfer matrix method (TMM) is introduced to study graphene plasmonic crystal (GPC) with periodic surface conductivity in the case of normal incidence. The introduction of TMM after considering the abnormal phase scattering of the abrupt interface gives an idea of how to accurately manipulate plasmonic crystal structures, and can reduce the calculation workload to a certain extent. The effectiveness of the proposed method is verified with the plane wave expansion method in our model. Furthermore, we study the defect mode and the plasmonic Tamm state in GPC by TMM.
Low-cross-talk and multi-channel heterogeneous 13-core four-LP mode fiber with a high refractive index ring and a trench
Authors: Shao Pengshuai , Li Shuguang , Li Jianshe , Meng Xiaojian , Guo Ying , Li Zenghui , Wang Luyao
Published: April 2022

We propose a heterogeneous 13-core few-mode fiber, which is characterized by the combination of a high refractive index ring and a trench. All cores of the optical fiber can stably transmit

L
P

01

,

L
P

11

,

L
P

21

, and

L
P

02

modes in the C

+

L band through structural optimization and numerical analysis. The effective refractive index difference of the

L
P

21

and

L
P

02

modes reaches

2

×

10

−
3

, which is conducive to the independent transmission of modes. The trench can effectively suppress the inter-core cross talk below

−

50

d
B

/

k
m

at 1550 nm. The proposed few-mode multi-core fiber is conducive to solving the long-distance signal transmission problem of large capacity and low cross talk in future optical communication systems.
Engineering the gain and bandwidth in avalanche photodetectors
Authors: Bartolo-Perez Cesar , Ahamed Ahasan , Mayet Ahmed S. , Rawat Amita , McPhillips Lisa , Ghandiparsi Soroush , Bec Julien , Ariño-Estrada Gerard , Cherry Simon , Wang Shih-Yuan , Marcu Laura , Saif Islam M.
Published: April 2022

Avalanche and Single-Photon Avalanche photodetectors (APDs and SPADs) rely on the probability of photogenerated carriers to trigger a multiplication process. Photon penetration depth plays a vital role in this process. In silicon APDs, a significant fraction of the short visible wavelengths is absorbed close to the device surface that is typically highly doped to serve as a contact. Most of the photogenerated carriers in this region can be lost by recombination, get slowly transported by diffusion, or multiplied with high excess noise. On the other hand, the extended penetration depth of near-infrared wavelengths requires thick semiconductors for efficient absorption. This diminishes the speed of the devices due to the long transit time in the thick absorption layer that is required for detecting most of these photons. Here, we demonstrate that it is possible to drive photons to a critical depth in a semiconductor film to maximize their gain-bandwidth performance and increase the absorption efficiency. This approach to engineering the penetration depth for different wavelengths in silicon is enabled by integrating photon-trapping nanoholes on the device surface. The penetration depth of short wavelengths such as 450 nm is increased from 0.25 µm to more than 0.62 µm. On the other hand, for a long-wavelength like 850 nm, the penetration depth is reduced from 18.3 µm to only 2.3 µm, decreasing the device transit time considerably. Such capabilities allow increasing the gain in APDs by almost 400× at 450 nm and by almost 9× at 850 nm. This engineering of the penetration depth in APDs would enable device designs requiring higher gain-bandwidth in emerging technologies such as Fluorescence Lifetime Microscopy (FLIM), Time-of-Flight Positron Emission Tomography (TOF-PET), quantum communications systems, and 3D imaging systems.
Numerical analysis of the effect of reduced temporal coherence in quantitative phase microscopy and tomography
Authors: Lipke Wojciech , Winnik Julianna , Trusiak Maciej
Published: April 2022

We present the numerical analysis of the effect of the temporarily partially coherent illumination on the phase measurement accuracy in digital holography microscopy (DHM) and optical diffraction tomography (ODT), as reconstruction algorithms tend to assume purely monochromatic conditions. In the regime of reduced temporal coherence, we simulate the hologram formation in two different optical setups, representing classical off-axis two-beam and grating common-path configurations. We consider two ODT variants: with sample rotation and angle-scanning of illumination. Besides the coherence degree of illumination, our simulation considers the influence of the sample normal dispersion, shape of the light spectrum, and optical parameters of the imaging setup. As reconstruction algorithms we employ Fourier hologram method and first-order Rytov approximation with direct inversion and nonnegativity constraints. Quantitative evaluation of the measurement results deviations introduced by the mentioned error sources is comprehensively analyzed, for the first time to the best of our knowledge. Obtained outcomes indicate low final DHM/ODT reconstruction errors for the grating-assisted common-path configuration. Nevertheless, dispersion and asymmetric spectrum introduce non-negligible overestimated refractive index values and noise, and should be thus carefully considered within experimental frameworks.
Hollow-core anti-resonant fiber based light-induced thermoelastic spectroscopy for gas sensing
Authors: Ma Yufei , Feng Wei , Qiao Shunda , Zhao Zixu , Gao ShouFei , Wang YingYing
Published: April 2022

In this paper, a hollow-core anti-resonant fiber (HC-ARF) based light-induced thermoelastic spectroscopy (LITES) sensor is reported. A custom-made silica-based HC-ARF with length of 75 cm was used as light medium and gas cell. Compared to a traditional multi-pass cell (MPC), the using of HC-ARF is advantageous for reducing the sensor size and easing the optical alignment. A quartz tuning fork (QTF) with a resonant frequency of 32766.20 Hz and quality factor of 12364.20 was adopted as the thermoelastic detector. Acetylene (C2H2) and carbon monoxide (CO) with absorption lines located at 6534.37 cm−1 (1530.37 nm) and 6380.30 cm−1 (1567.32 nm) were chosen as the target gas to verify such HC-ARF based LITES sensor performance. It was found that this HC-ARF based LITES sensor exhibits excellent linearity response to the analyte concentrations. The minimum detection limit (MDL) for C2H2 and CO detections were measured as 4.75 ppm and 1704 ppm, respectively. The MDL for such HC-ARF based LITES sensor can be further improved by using a HC-ARF with long length or choosing an absorption line with strong strength.
Allostery in the dynamic coactivator domain KIX occurs through minor conformational micro-states
Authors: Peiffer Amanda L. , Garlick Julie M. , Joy Stephen T. , Mapp Anna K. , Brooks Charles L.
Published: April 2022

The coactivator KIX of CBP uses two binding surfaces to recognize multiple activators and exhibits allostery in ternary complex formation. Activator•coactivator interactions are central to transcriptional regulation, yet the microscopic origins of allostery in dynamic proteins like KIX are largely unknown. Here, we investigate the molecular recognition and allosteric manifestations involved in two KIX ternary systems c-Myb•KIX•MLL and pKID•KIX•MLL. Exploring the hypothesis that binary complex formation prepays an entropic cost for positive cooperativity, we utilize molecular dynamics simulations, side chain methyl order parameters, and differential scanning fluorimetry (DSF) to explore conformational entropy changes in KIX. The protein’s configurational micro-states from structural clustering highlight the utility of protein plasticity in molecular recognition and allostery. We find that apo KIX occupies a wide distribution of lowly-populated configurational states. Each binding partner has its own suite of KIX states that it selects, building a model of molecular recognition fingerprints. Allostery is maximized with MLL pre-binding, which corresponds to the observation of a significant reduction in KIX micro-states observed when MLL binds. With all binding partners, the changes in KIX conformational entropy arise predominantly from changes in the most flexible loop. Likewise, we find that a small molecule and mutations allosterically inhibit/enhance activator binding by tuning loop dynamics, suggesting that loop-targeting chemical probes could be developed to alter KIX•activator interactions. Experimentally capturing KIX stabilization is challenging, particularly because of the disordered nature of particular activators. However, DSF melting curves allow for inference of relative entropic changes that occur across complexes, which we compare to our computed entropy changes using simulation methyl order parameters.
Mechanical properties of lithic raw materials from Kazakhstan: Comparing chert, shale, and porphyry
Authors: Namen Abay , Iovita Radu , Nickel Klaus G. , Varis Aristeidis , Taimagambetov Zhaken , Schmidt Patrick
Published: April 2022

The study of lithic raw material quality has become one of the major interpretive tools to investigate the raw material selection behaviour and its influence to the knapping technology. In order to make objective assessments of raw material quality, we need to measure their mechanical properties (e.g., fracture resistance, hardness, modulus of elasticity). However, such comprehensive investigations are lacking for the Palaeolithic of Kazakhstan. In this work, we investigate geological and archaeological lithic raw material samples of chert, porphyry, and shale collected from the Inner Asian Mountain Corridor (henceforth IAMC). Selected samples of aforementioned rocks were tested by means of Vickers and Knoop indentation methods to determine the main aspect of their mechanical properties: their indentation fracture resistance (a value closely related to fracture toughness). These tests were complemented by traditional petrographic studies to characterise the mineralogical composition and evaluate the level of impurities that could have potentially affected the mechanical properties. The results show that materials, such as porphyry possess fracture toughness values that can be compared to those of chert. Previously, porphyry was thought to be of lower quality due to the anisotropic composition and coarse feldspar and quartz phenocrysts embedded in a silica rich matrix. However, our analysis suggests that different raw materials are not different in terms of indentation fracture resistance. This work also offers first insight into the quality of archaeological porphyry that was utilised as a primary raw material at various Upper Palaeolithic sites in the Inner Asian Mountain Corridor from 47–21 ka cal BP.
Targeting pancreatic cancer with combinatorial treatment of CPI-613 and inhibitors of lactate metabolism
Authors: Kumstel Simone , Schreiber Tim , Goldstein Lea , Stenzel Jan , Lindner Tobias , Joksch Markus , Zhang Xianbin , Wendt Edgar Heinz Uwe , Schönrogge Maria , Krause Bernd , Vollmar Brigitte , Zechner Dietmar
Published: April 2022

Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of 10%. A stagnant high mortality rate over the last decades highlights the need for innovative therapeutic approaches. Pancreatic tumors pursue an altered metabolism in order to maintain energy generation under low nutrient influx and hypoxic conditions. Targeting these metabolic strategies might therefore be a reasonable therapeutic approach for pancreatic cancer. One promising agent is CPI- 613, a potent inhibitor of two enzymes of the tricarboxylic acid cycle. The present study evaluated the anti-cancerous efficacy of CPI-613 in combination with galloflavin, a lactate dehydrogenase inhibitor or with alpha-cyano-4-hydroxycinnamic acid, an inhibitor of monocarboxylate transporters. The efficacy of both combination therapies was tested in vitro on one human and two murine pancreatic cancer cell lines and in vivo in an orthotopic pancreatic cancer model. Tumor progression was evaluated by MRI and 18F-FDG PET-CT. Both combinatorial treatments demonstrated in vitro a significant inhibition of pancreatic cancer cell proliferation and induction of cell death. In contrast to the in vitro results, both combination therapies did not significantly reduce tumor growth in vivo. The in vitro results suggest that a combined inhibition of different metabolic pathways might be a promising approach for cancer therapy. However, the in vivo experiments indicate that applying a higher dosage or using other drugs targeting these metabolic pathways might be more promising.
Signs of left atrial disease and 10-year risk of atrial fibrillation
Authors: Uhe Tobias , Stegmann Tina , Langhammer Romy , Dagres Nikolaos , Laufs Ulrich , Wachter Rolf
Published: April 2022

Background

The contribution of left atrial disease and excessive supraventricular ectopic activity (ESVEA) to the risk for incident atrial fibrillation (AF) is incompletely understood.

Objective

To analyse the ten-year risk to develop AF in patients with cardiovascular risk factors and to define the impact of parameters of left atrial disease and ESVEA on AF risk.

Methods

148 patients from the Diast-CHF trial with at least one cardiovascular risk factor and free of AF at baseline were followed for 10 years. Left atrial disease was defined as left atrial volume index (LAVI) >35 ml/m2, P-terminal force in lead V1(PTFV1) >4000 ms*μV or elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) >250 pg/ml. We analyzed the association of these parameters and ESVEA (either >720 premature atrial contractions (PAC) or one atrial run >20 beats per day) on AF-free survival.

Results

After ten years, AF was newly detected in twelve patients (13.4%) with signs of left atrial disease and two patients (3.4%) without signs of left atrial disease (p = 0.04). LAVI (p = 0.005), ESVEA (p = 0.016) and NT-proBNP (p = 0.010) were significantly associated with AF-free survival in univariate analysis. A combined Cox model of left atrial disease parameters showed associations for NT-proBNP (HR 3.56; 95%CI 1.33–5.31; p = 0.04) and PAC (HR 2.66; 95%CI 1.25–10.15; p = 0.01) but not for LAVI or PTFV1with AF-free survival.

Conclusion

The risk for AF is higher in patients with cardiovascular risk factors and signs of left atrial disease. NT-proBNP and premature atrial contractions independently predict AF-free survival. The role of excessive supraventricular ectopic activity for the assessment of AF risk may be underestimated and requires further study.
Association between overweight and growth hormone secretion in patients with non-functioning pituitary tumors
Authors: Seki Yasufumi , Ichihara Atsuhiro
Published: April 2022

Introduction

Growth hormone (GH) deficiency (GHD) is often complicated by non-functioning pituitary tumors (NFPTs); however, its prevalence remains unclear because preoperative screening for GHD with provocative tests is not recommended. Accordingly, we attempted to clarify the characteristics of GHD in unoperated patients with NFPT.

Materials and methods

We retrospectively reviewed adult patients with non-functioning pituitary adenoma (NFPA) and Rathke’s cyst who underwent preoperative GH-releasing peptide-2 (GHRP-2) tests from January 2013 to December 2016. We investigated the association between peak GH response to GHRP-2 and background characteristics.

Results

Among 104 patients (85 NFPA and 19 Rathke’s cysts), 45 (43%) presented severe GHD, as diagnosed using GHRP-2 tests. Body mass index (β = -0.210, P = 0.007), free thyroxine (β = 0.440, P < 0.001), and tumor height (β = -0.254, P < 0.001) were significant variables for determining the peak GH response to GHRP-2 in multiple regression analyses. Overweight (odds ratio, 3.86; 95% confidence interval, 1.02–14.66) was significantly associated with severe GHD after adjustment for age, sex, creatinine, free thyroxine, tumor height and clinical diagnosis. The regression slopes between tumor height and peak GH response to GHRP-2 significantly differed between overweight patients and non-overweight individuals, as determined by analysis of covariance (P = 0.040). In the 48 patients who underwent postoperative GHRP-2 tests, severe postoperative GHD was significantly more common in overweight patients than non-overweight individuals (100% vs. 48%, P < 0.001).

Conclusion

We observed a negative synergistic effect between overweight and tumor size on GH secretion in patients with NFPTs, indicating that GH provocation tests for diagnosing underestimated GHD could be considered in overweight unoperated patients with large NFPTs.
Practice as research in animation: A provisional engagement
Authors: Nelson Robin
Published: April 2022

Let me start with a confession. Though for years, I have had an interest in animation and have observed students engaged in puppet, paper and plasticine processes of animation by analogue and digital means, I have myself never constructed an animated sequence. Why, then, have I been invited to write a contribution to this collection? For philosophical and political reasons related to a lifelong engagement with arts and screen media practices and education, I have developed expertise in what some call artistic research and I prefer to call practice as research (PaR). In particular, I have developed an epistemological model for PaR, which sets three modes of knowing – know-how, know-what and know-that – in dynamic inter-relation. In what follows, I place my specialist terms in italics to mark them out.
Multimodality as a Limit of Narrative in Mark Z. Danielewski's The Familiar
Authors: Pöhlmann Sascha
Published: April 2022

In this article, Pöhlmann reads Mark Z. Danielewski's pentalogy »The Familiar« to show how the textual, visual, and material aspects of this multimodal text combine beyond ekphrasis or illustration and how they expose, challenge, and transgress the boundary between narrative and nonnarrative features without dissolving or reinforcing it.
Od Redakcji
Authors: Czasopisma Redakcja
Published: April 2022

Od Redakcji
Michał Spandowski, Catalogue of Incunabula in the National Library of Poland, in collaboration with Sławomir Szyller, description of bookbindings prepared by Maria Brynda, translation: Elżbieta Olechowska, vol. I, Warszawa: Biblioteka Narodowa 2020, s. 694 [1]. ISBN 978-83-7009-833-6
Authors: Łukaszewski Jakub
Published: April 2022

Recenzja: Michał Spandowski, Catalogue of Incunabula in the National Library of Poland, in collaboration with Sławomir Szyller, description of bookbindings prepared by Maria Brynda, translation: Elżbieta Olechowska, vol. I, Warszawa: Biblioteka Narodowa 2020, s. 694 [1]. ISBN 978-83-7009-833-6
Małgorzata Kisilowska, Biblioteki publiczne w kryzysie: doświadczenie pierwszego etapu pandemii, Warszawa: SBP 2021 (Nauka – Dydaktyka – Praktyka), s. 276. IS BN 978-83-65741-69-1
Authors: Mikołajska Aleksandra
Published: April 2022

Recenzja: Małgorzata Kisilowska, Biblioteki publiczne w kryzysie: doświadczenie pierwszego etapu pandemii, Warszawa: SBP 2021 (Nauka – Dydaktyka – Praktyka), s. 276. IS BN 978-83-65741-69-1
Halina Basińska (1954–2021)
Authors: Karasiak Katarzyna
Published: April 2022

Wspomnienia: Halina Basińska (1954–2021)
Szyfr Jana Żdżarowskiego (-1551) na tle metod kryptograficznych używanych w Polsce pierwszej połowy XVI w.
Authors: Łukaszewski Jakub
Published: April 2022

Artykuł poświęcony jest analizie szyfrowanych zapisek w diariuszu należącym do poznańskiego kanonika, Jana Żdżarowskiego (zm. 1551). Jego metody kryptograficzne zaprezentowano na szerszym tle. Pierwsza część tekstu to omówienie podstawowych metod kryptograficznych używanych w Polsce w pierwszej połowie XVI wieku. Początkowo stosowano zapisy alfabetem innym niż łaciński (posługiwano się cyrylicą lub alfabetami greckim i hebrajskim), następnie utrwaliły się dwa rodzaje szyfrów podstawieniowych: monoalfabetycznego i prostego szyfru homofonicznego wzbogaconego o nomenklatory. Wstępne zestawienie znanych przykładów użycia kryptografii w Polsce wskazuje, że najpierw używano jej przede wszystkim w kancelarii królewskiej, aby utajnić poufną korespondencję dyplomatyczną. Stosowane tam metody bardzo szybko wykorzystano do celów prywatnych – osobistych zapisek diariuszowych. W drugiej części artykułu opisane zostały przykłady szyfrowania zapisek w diariuszach spisywanych na kartach drukowanych wielorocznych kalendarzy (almanachów i efemeryd). Zidentyfikowane zostały cztery takie diariusze. Trzy z nich należały do duchownych: Macieja Drzewickiego (1467–1535), Jana Żdżarowskiego (zm. 1551) i Piotra Myszkowskiego (ca 1505–1591), czwarty, anonimowy, zawiera dwa szyfrogramy z 1534 roku. Drzewicki i Myszkowski utajniali informacje w swych diariuszach, zapisując informacje w języku łacińskim za pomocą cyrylicy i alfabetu greckiego. Anonim z 1534 roku oraz Jan Żdżarowski stosowali proste szyfry podstawieniowe monoalfabetyczne. W poufnej korespondencji dyplomatycznej, jak i w diariuszach kryptografia pełniła taką samą funkcję. Służyła utajnianiu informacji. Szyfry Żdżarowskiego (ich odczyt zaprezentowano w tekście artykułu) kryły informacje o zabójstwie ks. Jana Łukomskiego (w które Żdżarowski był wplątany) oraz o narodzinach jego syna Macieja. Drzewicki szyfrował np. swe pożyczki pieniężne dla kanclerza Jana Łaskiego, a ks. Myszkowski utajniał m.in. wzmianki o nasilających się objawach trapiącej go rzeżączki. Na przykładzie zapisek diariuszowych Żdżarowskiego wykazano, że diariusze nie były materiałem ściśle osobistym, wgląd w nie miewały osoby postronne. Analizowane szyfrowane wpisy ukrywały wstydliwe fakty. Były to jednak fakty na tyle istotne i użyteczne dla ich właścicieli, że postanawiali je upamiętnić, ale za pomocą szyfrogramów. Do artykułu dołączono Aneks zawierający wstępny wykaz metod kryptograficznych stosowanych w Polsce do połowy XVI wieku.
Cooperative transportation: realizing the promises of robotic networks using a tailored software/hardware architecture
Authors: Ebel Henrik , Eberhard Peter
Published: April 2022

With cooperative transportation, the paper looks at a demanding problem from distributed robotics. At its heart, the proposed transportation scheme uses distributed model predictive control. Yet, distributed control alone does not suffice to solve the task. Thus, also distributed organization, a custom software architecture, simulation, and custom robotic hardware are dealt with, bridging the gap between distributed control theory and practical robotics. The robots are enabled to transport arbitrarily-shaped objects, automatically adapting to changing circumstances and numbers of robots.
Rollout event-triggered control: reconciling event- and time-triggered control
Authors: Wildhagen Stefan , Dürr Frank , Allgöwer Frank
Published: April 2022

Event-triggered control (ETC) and time-triggered control (TTC), the classical concepts to determine the transmission instants for networked control systems, each come with drawbacks: It is difficult to tune ETC such that a certain bandwidth is respected, whereas TTC cannot adapt the sampling interval to the current state of the control system. In this article, we provide an overview over rollout ETC, a method aimed at reconciling the advantages of ETC and TTC. We unite two variants of rollout ETC under a common framework and present conditions for convergence and compliance with a predefined bandwidth limit. Furthermore, we demonstrate that rollout ETC satisfies a performance bound and that it allows for a very flexible transmission scheduling similar to classical ETC. The mentioned beneficial properties are illustrated through extensive numerical simulations.
The ChristologicalPerichōrēsisand Dance
Authors: Hikota Riyako Cecilia
Published: April 2022

In order to take the physical and incorporeal dimension of dance seriously in the context of Christian theology, we propose that it should be the neglected ChristologicalPerichōrēsis(as well as concepts and ideas surrounding it) rather than the TrinitarianPerichōrēsisthat is historically and traditionally relevant as a source of a dialogue between Christian theology and dance. First, we propose that the guiding metaphor should beChrist as dancer, historical examples of which already exist unlike with the notion of the Trinity as dance. Then, we look at St Maximus the Confessor’s Christocentric cosmology. With the human being understood as a “microcosm” of body–soul(spirit) unity placed at the center of the entire creation, his Christocentric cosmology could be a potential source for enhancing a dialogue between Christian theology and dance, while helping us overcome the dualistic separation between the body and the spirit and consequently between nature and culture.
Gesellschaftsrecht im Spiegel seiner Habilitationsschriften
Authors: Fleischer Holger
Published: April 2022

Habilitationsschriften haben wesentlich zum wissenschaftlichen Fortschritt im Gesellschaftsrecht beigetragen. Der vorliegende Beitrag erschließt erstmals den enormen Korpus einschlägiger Arbeiten aus den letzten acht Jahrzehnten. Zugleich geht er auf ihre Besonderheiten ein und analysiert ihre thematische Spannbreite, ihre methodischen Zugriffe und ihre Rezeption in Rechtsprechung und Rechtslehre.
Aufsichtsratsvergütung und nahestehende Dritte
Authors: Told Julia
Published: April 2022

Hinweis

Vergütungsgrenzen von Aufsichtsratsmitgliedern ergeben sich aus § 113 und § 114 AktG. Beide Bestimmungen fokussieren auf Leistungen der Aktiengesellschaft an Aufsichtsratsmitglieder und nehmen nahestehende Dritte nicht in den Blick. Dennoch rechnet der BGH in den Ausgangsentscheidungen Vergütungen an nahestehende Dritte dem Aufsichtsratsmitglied zu. Leistungen von gewissen Dritten behandelt er als solche der Aktiengesellschaft. Der Beitrag befasst sich aus diesem Anlass mit dem Grundlagen und Grenzen der Erstreckung des Normanwendungsbereichs der §§ 113 f AktG auf nahestehende Dritte.
Chronic unilateral leg warty lesion: clinical image and literature review
Authors: Pujahar Aswini K
Published: April 2022

54 years old diabetic male presented with history of with painless multiple progressive warty lesions on the right lower two third of the left leg remain undiagnosed for twelve years. It was spreading and growing relentlessly, not responding to medication prescribed by multiple doctors and patient thought of a uncurable disease. The biopsy came confirmatory. Antifungal therapy along with surgical excision hasten up the healing. An adequate biopsy is a must in undiagnosed skin lesion. Specific medical therapy and adjuvant surgery give early relief.
Priorities for the Quality Development of Preschool Education
Authors: NOVIKOV V. M.
Published: April 2022

Further development of preschool education is associated with the introduction of innovative educational technologies, the use of modern methods and tools for the functioning of preschool institutions, improving their structure and strengthening the resource base. It is important to realize that the assessment of the quality of education in preschool institutions is a motivational tool for the implementation of these global trends. It confirms the critical importance and economic efficiency of the early development of children for their future life prospects from the point of view of pedagogy and psychophysiology. An independent assessment of the quality of curriculum is the most important means of informing society about making cardinal decisions about the future development of the preschool education system. The purpose of the article is to determine the conditions for creating an adequate environment for the development of the preschool contingent of children, taking into account the experience of foreign countries. The research methods are analog, tabular, variations for the analysis of quantitative changes in the value of the studied feature (budget costs). Novelty. The results obtained during the study, primarily on the development of subject-resource environment of preschool institutions, as well as the characteristics of scales for assessing the quality of preschool education provide an opportunity to improve the strategy of preschool education, adjust educational programs and improve the professional level of preschool teachers. The statistic contains the characteristic «Scales for a comprehensive assessment of the quality of education in preschool organizations». Analytical assessments of the basic components of educational robots for preschool mortgages. In order to use them to assess the quality of educational activities of preschool organizations, the emphasis is shifted from analyzing learning outcomes to determining the potential of the resource base of preschool institutions. In the absence of reliable guarantees from the state for obtaining high-quality preschool education, certain steps are proposed aimed at leveling the starting opportunities for access to education in modern preschool institutions.
A busca por direitos humanos
Authors: Soares Evanway Sellberg
Published: April 2022

Devido à crescente influência religiosa no discurso político contra minorias sexuais e de identidade de gênero, este artigo busca apresentar alternativas religiosas de valorização dessas identidades, seus processos de formação e meios de ação no meio público. Para isso, é realizada a análise de dados obtidos em observação participante na Igreja da Comunidade Metropolitana a partir da perspectiva de Habermas e Honneth, contribuindo para o debate sobre a atualidade da Teoria Crítica como ferramenta de análise. Fica constatado que as ações da denominação no espaço público na luta por direitos LGBT está baseada num processo de luta por reconhecimento social, gerando uma disputa não somente discursiva, mas também em ações políticas no espaço público, visando a transformação da sociedade. Ao fazer isso, a denominação se torna um braço religioso no movimento LGBT mais amplo, dialogando tanto com outras denominações, quanto com a sociedade de modo mais amplo.
“Spiritual Formation for Civic Life in the Neo-Calvinist Tradition”
Authors: DeMoor Michael
Published: April 2022

This paper offers an overview of how the neo-Calvinist tradition (originating in the late nineteenth century Netherlands) understood and practiced spiritual formation in order to prepare its members for civic life. It reflects on how the distinctive understanding of public life in the tradition shaped these practices and suggests that this helps to explain the contemporary situation of the movement.
Ritual Gone Wrong: What We Learn from Ritual Disruption, by Kathryn T. McClymond
Authors: DeMaris Richard
Published: April 2022

Ritual Gone Wrong: What We Learn from Ritual Disruption, by Kathryn T. McClymond. Oxford Ritual Studies. Oxford University Press, 2016. 242 + x pp. Pb., 35.00 USD. ISBN: 978–0–19–979092–0.
Prospects of VAT Administration Improvement in Digitalized World: Analytical Review
Authors:   Institute of Industrial Economics of NAS of Ukraine, Kyiv, Ukraine, Harkushenko O.N.
Published: April 2022

In conditions of integral digitalization, governments may face a shortfall in VAT revenues due to tax avoidance and frauds. Here arise two opposite hypotheses: 1) digital technologies can solve problems with VAT; 2) digital technologies are not capable to do so. The purpose of the study is to conduct an analytical review of the main problems and ways to improve the administration of VAT in the context of the digitalization of the economy. To achieve this, literature on digital technologies in VAT administration was analyzed. The literature sample consists of 25 sources on e-invoicing and 27 sources on blockchain in VAT administration. The main criteria for literature selection are: accessibility and significance of source; time horizon (last 10–15 years); keywords (“e-invoicing”, “blockchain”, “VAT”, “taxation”, “tax administration”); interdisciplinary approach (literature set represent standpoints of experts from different fields). It was established, that there is no consensus about e-invoicing and blockchain in VAT administration. These technologies have both shortcomings and advantages. The main result of the review is this: digital technologies are not a panacea for solving all problems with VAT administration. That is, both hypothesis of this paper is not proved, but not refuted. Digital technologies can simplify and reduce costs on VAT administration, provided there is a developed ICT infrastructure and consistent regulatory framework, a high tax culture, a low level of “shadow” economy. Interaction between countries in terms of the tax information exchange is also crucial. If these conditions are met, digital technologies in taxation can be effectively employed in the next 5–10 years in the most advanced countries; less developed countries will need much more time for this.
Tax Education and the Attitude of University Students Towards Tax Consciousness: The Case of University of Externado (Colombia)
Authors:   Universidad Externado de Colombia, Bogota, Colombia, Yepes-López G. A. , Gergerlioğlu U. ,   Hitit University, Çorum, Turkey
Published: April 2022

Many studies have been conducted on the effect of tax education on tax consciousness, however, no study that reveals such an effect has been conducted in Latin America. In this context, we aimed to analyze whether there is a significant difference between the attitudes towards tax consciousness of students who took tax courses and those who did not take tax courses at the University of Externado in Colombia. The data regarding 538 surveys were taken into account for analysis and testing. A 5-point Likert scale was used for the attitude items in the survey. It was observed that the data on attitude items did not show a normal distribution. Therefore, non-parametric tests were used for the data subject to our survey. In this context, the relationship between the demographic data (gender, marital status, work status) and the attitude items were analyzed through Mann Whitney U and Kruskal Wallis H tests. The test results of our study for gender and marital status showed that female students compared to males and married students compared to single and engaged students showed more supportive attitudes towards consciousness. Additionally, the students who define their own tax consciousness level as high revealed more supportive attitudes towards tax education. As the results of our analysis revealed that there is not much difference among the attitudes of students who received tax courses and those who did not receive tax courses, it would be beneficial for comparability to carry out such a study in universities in other countries located in Latin America.
Development, validation and international certification of a health portal for people with disabilities
Authors: Cintra Michel Marcossi , Faleiros Fabiana , Corbo Letícia Noelle , Okano Larissa Miyuki , Vedana Kelly Graziani Giacchero , Dessotte Carina Aparecida Marosti , Kaeppler Christoph
Published: April 2022

ABSTRACT Objectives: to develop, validate with specialists and internationally certify a virtual health portal, the D+Informação. Methods: a quantitative methodological study. Twenty-two expert judges validated the Portal in the health and computer science areas using the Content Validity Index and the Gwet test. International certification followed HONcode principles® to ensure the trust of information. Results: judges of health and computer science validated the portal obtaining a minimum Content Validity Index in more than 75% of the topics, in addition to the evaluation of general agreement, 0.253; content evaluation, 0.193, and interface evaluation, 0.230. All presented the value of Gwet with p ≤ 0,001. Conclusions: the portal D+Informação was developed, validated, internationally certified and is hosted on this website: https://demaisinformacao.com.br
Violence against children and adolescents: nurse’s actions in primary health care
Authors: Marcolino Emanuella de Castro , Santos Renata Clemente dos , Clementino Francisco de Sales , Souto Rafaella Queiroga , Silva Glauber Weder dos Santos , Miranda Francisco Arnoldo Nunes de
Published: April 2022

ABSTRACT Objectives: to analyze the role of nurses in suspected or confirmed cases of violence against children and adolescents in Primary Health Care. Methods: an analytical research, with a qualitative approach. Thirty nurses participated in the study, and data were collected by means of an individual form and a semi-structured interview. The data received lexicographic analysis by the software IRaMuTeQ (Interface de R pour les Analyses Multidimensionnelles de Textes et de Questionnaires) organized by Bardin’s content analysis. Results: five categories emerged, in which it was possible to consider that the nurses’ approach in cases of violence was based on the identification of violence through physical examination during nursing consultations, health promotion actions in the school environment, request for support from the multi-professional team, and transfer of responsibilities. Final Considerations: it is inferred that the fragility in the professional training of nurses to address situations of violence against children and adolescents produces deficits in comprehensive care for victims.
A abertura financeira dos países periféricos e os determinantes dos fluxos de capitais
Authors: PRATES DANIELA MAGALHÃES
Published: April 2022

RESUMO Este artigo discute duas linhas de análise sobre a abertura financeira nos países em desenvolvimento. Economistas convencionais argumentam que a abertura traz várias vantagens para esses países se as reformas liberalizantes tiverem sido feitas na sequência adequada, com a liberalização dos fluxos de capital como a última reforma adotada. A hipótese central assumida é que os fluxos são guiados por fundamentos econômicos. Uma abordagem alternativa, com base teórica pós-keynesiana, enfatiza que, no atual contexto de globalização financeira e predominância de fluxos de carteira, os fluxos de capital não são guiados por fundamentos, mas por perspectivas de curto prazo e por fatores exógenos ao país específico e, portanto, pode ser revertida a qualquer momento, com impactos negativos no país em desenvolvimento.
Apoio institucional na Atenção Primária em Saúde no Brasil: uma revisão integrativa
Authors: Brito Christiane da Silva , Santos Hebert Luan Pereira Campos dos , Maciel Fernanda Beatriz Melo , Martins Poliana Cardoso , Prado Nília Maria de Brito Lima
Published: April 2022

Resumo Um dos grandes desafios do Sistema Único de Saúde é a necessidade de transcender o caráter disciplinador e controlador da gestão e fomentar a função democrática, para possibilitar uma maior participação de trabalhadores e comunidade na gestão em saúde. Com o intuito de identificar e sintetizar definições e práticas de apoio institucional implementadas no âmbito da Atenção Primária à Saúde no Brasil, de acordo com o método Paidéia, que preconiza democratização institucional e a qualificação do atendimento à população através de novos arranjos e dispositivos de gestão e do processo trabalho, foi desenvolvida uma revisão integrativa da literatura referente ao período de 2005 a 2019. O corpus de análise contemplou 24 publicações que explicitaram definições e aspectos operacionais incipientes, fragilidades na integração entre o âmbito da clínica ampliada e da gestão compartilhada que deveria se dar na dialética entre o Apoio Institucional e o Apoio Matricial, a necessidade de fortalecer a função do apoiador institucional, enquanto mediador metodológico e de reformular os tradicionais mecanismos de gestão e as estratégias para educação permanente em saúde no âmbito do Sistema Único de Saúde.
O que revela o Índice de Qualidade da Dieta associado ao Guia Alimentar Digital comparativamente a outro índice, em idosos?
Authors: Assumpção Daniela de , Caivano Simone , Corona Ligiana Pires , Barros Marilisa Berti de Azevedo , Barros Filho Antonio de Azevedo , Domene Semíramis Martins Álvares
Published: April 2022

Resumo Objetivou-se avaliar o Índice de Qualidade da Dieta associado ao Guia Alimentar Digital (IQD-GAD) em comparação a outro mais utilizado e difundido na literatura, o Índice de Qualidade da Dieta Revisado (IQD-R). Estudo transversal de base populacional, com 822 idosos (≥ 60 anos) de Campinas, São Paulo. Utilizaram-se dados de um recordatório de 24 horas para efetuar os indicadores, cujas pontuações globais variam de zero a cem: quanto maior, melhor é a qualidade. Regressão linear simples e múltipla foi aplicada nas análises. O IQD-R resultou em maior pontuação global do que o IQD-GAD (62,9 vs. 47,5). No IQD-R, os escores médios foram melhores nos mais longevos e piores nos mais escolarizados e nos tabagistas. Quanto aos escores do IQD-GAD, não foram detectadas diferenças significativas em idade, escolaridade e tabagismo, mas foram maiores em segmentos de maior renda. Os componentes com piores pontuações: cereais integrais, sódio e leite (IQD-R); frutas, cereais integrais, raízes/tubérculos, leite, cereais refinados e carne vermelha/processada (IQD-GAD). Observaram-se discrepâncias nos escores globais e dos componentes dos indicadores, que refletem importantes diferenças metodológicas. Investigações dessa natureza configuram uma oportunidade de aprimorar a sensibilidade de indicadores a aspectos particulares da alimentação.
Desempenho do serviço de atendimento móvel de urgência na perspectiva de gestores e profissionais: estudo de caso em região do estado de São Paulo, Brasil
Authors: Oliveira Catia Cristina Martins de , O’Dwyer Gisele , Novaes Hillegonda Maria Dutilh
Published: April 2022

Resumo Este artigo tem como objetivo analisar a perspectiva de gestores e profissionais sobre o desempenho do SAMU na região do Grande ABC. Trata-se de estudo de caso, de abordagem qualitativa, baseado na formulação de modelo teórico-lógico da intervenção e entrevistas semiestruturadas. O Modelo teórico-lógico traduziu as dimensões de análise do SAMU: regulação, assistência e gestão. O processo de regulação foi entendido como espaço estratégico onde o julgamento da necessidade do paciente e o tempo de despacho da ambulância tem potencial de influenciar nos desfechos dos casos transportados. Na assistência os principais temas que emergiram foram investimento na qualificação da equipe e em telemedicina com a perspectiva de melhorar a qualidade do cuidado e tornar o diagnóstico mais preciso. No âmbito da gestão desafios como integração do SAMU com centros terciários, aperfeiçoamento do sistema de informação e monitoramento e avaliação foram destacados visando qualificar os processos regulatórios alinhando-os aos objetivos propostos na política de saúde. O conjunto de dados analisados reforça a capacidade do SAMU na atenção de urgência na região, no entanto a intervenção precisa superar importantes desafios em busca de melhor prognóstico entre os casos transportados.
Incidência de aumento e redução do Índice de Massa Corporal na meia-idade: seguimento de quatro anos
Authors: Augusto Nathalia Assis , Loch Mathias Roberto , Dias Douglas Fernando , Silva Ana Maria Rigo
Published: April 2022

Resumo Objetivou-se analisar a incidência de aumento e de redução do Índice de Massa Corporal (IMC) entre homens e mulheres de meia-idade segundo características sociodemográficas e classificação do estado nutricional. Trata-se de uma coorte de base populacional com 689 adultos com idade entre 40 e 64 anos seguidos por quatro anos. Verificou-se a proporção de redução e de aumento do IMC (≥1 kg/m²) segundo variáveis sociodemográficas e classificação do estado nutricional na linha de base mediante regressão de Poisson bruta e ajustada. A maior incidência de redução do IMC foi observada entre os homens na faixa etária de 55 a 64 anos (RR: 1,78; IC95%: 1,06-3,00), naqueles sem companheira (RR: 1,85; IC95%: 1,09-3,14), nos classificados com sobrepeso (RR: 2,06; IC95%: 1,13-3,74) e obesidade (RR: 2,33; IC95%: 1,24-4,35), e entre as mulheres na faixa etária de 55 a 64 anos (RR: 1,43; IC95%: 1,02-2,00) e nas classificadas com obesidade (RR: 2,10; IC95%: 1,30-3,38). A incidência de aumento do IMC foi menor na faixa etária de 55 a 64 anos entre os homens (RR: 0,62; IC95%: 0,41-0,95) e mulheres (RR: 0,68; IC95%: 0,49-0,95). Estes dados são importantes para compreensão dos fatores relacionados à variação do IMC e elaboração de políticas públicas que visem o cuidado à saúde na meia-idade.
Condição periodontal de adultos em situação de rua temporariamente institucionalizados e fatores associados
Authors: Machado Tamires Gomes de Oliveira , Lawder Juliana Aparecida Campos , Souza João Batista de , Matos Marcos André de , Freire Maria do Carmo Matias
Published: April 2022

Resumo O objetivo deste estudo transversal foi descrever a condição periodontal e sua associação com fatores sociodemográficos, comportamentos em saúde bucal e uso de drogas entre indivíduos em situação de rua temporariamente institucionalizados. Os dados foram coletados por meio de exame clínico e questionário com 102 adultos atendidos na única instituição pública para este grupo em Goiânia, Goiás. A condição periodontal foi avaliada pela presença de sangramento à sondagem, cálculo dentário e bolsas, de acordo com o Índice Periodontal Comunitário (CPI). Foram realizados o teste Qui-quadrado e regressões de Poisson com variância robusta. A prevalência de CPI>1 foi de 83,3%. Cerca de 68,0% da amostra apresentou sangramento, 82,4% cálculo e 9,8% bolsa periodontal. Nas análises bivariadas, os que tinham usado drogas ilícitas alguma vez tinham maior prevalência de cálculo; os homens e os indivíduos sem união estável tinham maior prevalência de bolsa. Na análise ajustada, indivíduos que usavam fio dental tiveram menor prevalência de sangramento (RP=0,58; IC95%=0,35-0,96). As demais covariáveis não foram associadas aos desfechos. Concluiu-se que a prevalência de alteração periodontal foi alta, houve predomínio de cálculo e a única associação independente foi entre sangramento e uso de fio dental.
Intersetorialidade e saúde nas políticas estaduais de segurança pública e de prevenção à violência no Brasil
Authors: Oliveira Daniela Cristina Neves de , Lico Fátima Madalena de Campos , Pereira Hegle Mariano Silva , Regina Fernanda Lopes , Peres Maria Fernanda Tourinho
Published: April 2022

Resumo O presente estudo tem como objetivo compreender de que forma os Planos Estaduais de Segurança Pública (PSP) incorporam a perspectiva da prevenção da violência e da intersetorialidade, com especial atenção para o papel do setor Saúde. Trata-se de um estudo qualitativo que utilizou as técnicas de análise documental e de conteúdo, tendo como material empírico os PSP implementados ou em fase de formulação. Foram identificados 14 PSP. Todos os planos incorporam as concepções de prevenção da violência, intersetorialidade e participação do setor saúde. A concepção de prevenção da violência decorre do conceito de segurança cidadã, mas ações específicas de prevenção são mencionadas de forma genérica. A incorporação da intersetorialidade é heterogênea e insuficiente, na medida em que a participação dos setores na fase de planejamento não é a regra. A participação do setor saúde nem sempre é ativa, ou seja, desde a fase de planejamento das ações, as quais, na maioria das vezes, são pontuais e assistenciais. O setor saúde assume, ainda, um papel secundário, sem que suas experiências e potencialidades sejam reconhecidas. Concepções de prevenção da violência, intersetorialidade e participação do setor saúde, estão presentes nos planos de forma incipiente. Ressalta-se a importância de novos estudos.