bluuebunny/crossref_metadata_2025 huggingface dataset:
Province clustering based on the percentage of communicable disease using the BCBimax biclustering algorithm
Authors: Aidi Muhammad Nur , Wulandari Cynthia , Oktarina Sachnaz Desta , Aditra Taufiqur Rakhim , Ernawati Fitrah , Efriwati Efriwati , Nurjanah Nunung , Rachmawati Rika , Julianti Elisa Diana , Sundari Dian , Retiaty Fifi , Arifin Aya Yuriestia , Dewi Rita Marleta , Nazaruddin Nazarina , Salimar Salimar , Fuada Noviati , Widodo Yekti , Setyawati Budi , Nurhidayati Nuzuliyati , Sudikno Sudikno , Irawan Irlina Raswanti , Widoretno Widoretno
Published: September 2023

Indonesia needs to lower its high infectious disease rate. This requires reliable data and following their temporal changes across provinces. We investigated the benefits of surveying the epidemiological situation with the imax biclustering algorithm using secondary data from a recent national scale survey of main infectious diseases from the National Basic Health Research (Riskesdas) covering 34 provinces in Indonesia. Hierarchical and k-means clustering can only handle one data source, but BCBimax biclustering can cluster rows and columns in a data matrix. Several experiments determined the best row and column threshold values, which is crucial for a useful result. The percentages of Indonesia’s seven most common infectious diseases (ARI, pneumonia, diarrhoea, tuberculosis (TB), hepatitis, malaria, and filariasis) were ordered by province to form groups without considering proximity because clusters are usually far apart. ARI, pneumonia, and diarrhoea were divided into toddler and adult infections, making 10 target diseases instead of seven. The set of biclusters formed based on the presence and level of these diseases included 7 diseases with moderate to high disease levels, 5 diseases (formed by 2 clusters), 3 diseases, 2 diseases, and a final order that only included adult diarrhoea. In 6 of 8 clusters, diarrhea was the most prevalent infectious disease in Indonesia, making its eradication a priority. Direct person-to-person infections like ARI, pneumonia, TB, and diarrhoea were found in 4-6 of 8 clusters. These diseases are more common and spread faster than vector-borne diseases like malaria and filariasis, making them more important.
Pleural effusion and Waldenström macroglobulinemia: if cytology and flow cytometric findings do not match. A case report
Authors: Stirpe Emanuele , Bardaro Floriana , Köhl Johanna
Published: September 2023

Pleural effusion is a rare complication of lymphoplasmacytic lymphoma. When it occurs, traditional investigation techniques may not always be successful. The flow cytometry is a fast and precise diagnostic technique, which can be helpful in the diagnosis of pleural localization of hematological diseases. We present a case report of a pleural localization of Waldenström macroglobulinaemia detected by flow cytometry.
Cross-sectional study comparing anxiety and depression amongs high-risk and normal pregnant women
Authors: Kesavareddy Sudha Rani , Ramnaik Azmeera , Chandrasekhar B. , Nagadevara Uma Sundari
Published: September 2023

Background:

Pregnancy is an important period in women’s life that induces a lot of physical and psychological changes. Failure to cope up with increased demand she may develop psychological problems such as anxiety and depression that result in adverse maternal and fetal outcomes. The risk may be more with high-risk pregnancy.

Methods:

The present study, conducted in a tertiary care hospital compared depression and anxiety amongst high-risk and normal pregnant women. Each group (n = 50) was administered a semi-structured proforma to collect socio-demographic variables and Hamilton Anxiety Scale (HAM-A), Hamilton Depression Rating (HAM-D) Scale and Edinburgh Postnatal Depression Scale (EPDS) scales were applied.

Results:

Socio-demographic variables had no impact on anxiety and depression scores. The mean HAM-D, HAM-A and EPDS scores were significantly higher (10.5, 12.4 and10.1 respectively) in high-risk pregnant women compared to normal pregnant women (7.1, 10.6 and 7.48, respectively).

Conclusions:

High-risk pregnant women showed statistically significantly higher mean scores in all scales namely HAM-A, HAM-D and EPDS.
Comparison of posttraumatic growth and posttraumatic stress of nurses with physicians and medical students after caring of COVID-19 patients
Authors: AKBARI Roghayeh , FARAMARZI Mahbobeh , GHOLINIA Hemmat
Published: September 2023

Objectives:

The present study compared the prevalence and psychosocial factors affecting posttraumatic growth (PTG), posttraumatic stress disorder (PTSD), and psychological distress in nurses, physicians, and medical students.

Materials and Methods:

In a cross-sectional study, three groups of medical staff including nurses (n = 57), physicians (n = 40), and medical students (n = 34) who were responsible for the care/treatment of COVID-19 patients admitted to a general hospital for 4 months responded to Posttraumatic Growth Inventory, Brief Symptom Inventory-18, Resilience Questionnaire, PTSD Screen, and Social Capital-Integrated Questionnaire.

Results:

After the exposure of medical staff to at least 4 months of treatment/care of COVID-19 patients, PTG prevalence was higher than PTSD (38.2% vs. 14.6%), but they experienced some degrees of psychological distress (65.5%). The nurses had 8.33 (confidence interval [CI]: 2.5–26.7) times higher PTG rate than medical students (P < 0.001). Physicists also experienced 5.00 (CI: 1.4–26.7) times higher PTG than medical students (P < 0.001). PTG was aided by age, married status, strong resilience, and high social capital, but gender had no influence. Resilience played an important protective role to prevent the incidence of psychological distress in nurses, medical students, and physicians.

Conclusion:

Despite the fact that the PTSD and psychological distress were same in the three groups of medical staff, the nurses had a greater rate of PTG than physicians and medical students.
Impact of designed infection control educational program on nurses' knowledge and compliance with standard precautions at maternity hospitals
Authors: ZAGHLOUL-MAHMOUD Fatma , GAMAL-MOSTAFA Mohamed , MAHMOUD-ABDEL-RAHMAN Walaa
Published: September 2023

Objectives:

This study aimed to assess the nurses' knowledge and compliance with infection control standard precautions and evaluate the impact of the designed infection control educational program on nurses' knowledge and compliance with standard precautions at the maternity hospital.

Materials and Methods:

A quasi-experimental one-group pretest-posttest design was used on convenient sample of 60 nurses working at Obstetrics and Gynecological hospital in Cairo University Hospital, Kasr El Ainy, who received “designed infection control educational program” for 6 months. The data were collected through the questionnaire comprising demographics, knowledge, and compliance with standard precautions questionnaire. The nurses' knowledge and compliance score were compared before and after intervention.

Results:

The studied nurses had higher level of knowledge (85.3%) and compliance (92.8%) regarding infection control standard precautions after the educational program compared to before the program. The results revealed statistically significant difference between before and after the program regarding nurses' knowledge score (15.5 ± 2.9 vs. 17.1 ± 1.6, P < 0.001) and compliance score (58.5 ± 13.2 vs. 74.3 ± 5.1, P < 0.001). In addition, there was insignificant relation between nurses' knowledge and compliance with standard precautions both before (r = 0.952, P = 0.474) and after educational program (r = 0.164, P = 0.223).

Conclusion:

The nurses' level of knowledge and compliance regarding infection control standard precautions was significantly improved after the program. Therefore, it is recommended that periodical educational programs regarding the standard precautions of infection control are essential for nurses at maternity hospital.
Prevalence of social media addiction among nursing students
Authors: SHABAN Marwa Mamdouh , ABDOU Nagah Mahmoud , EID Mahmoud Magdy , IBRAHIM Mostafa Ahmed , METWALY Mohammed El Dean , SAYED Mohamed Abdeltwab , MANSOUR Youmna Magdy Abdulwahab , RAMADAN Fatma Saad
Published: September 2023

Objective:

The objective of this study was to assess the prevalence and level of social media addiction among nursing students in the Faculty of Nursing, Cairo University.

Materials and Methods:

A descriptive cross-sectional research design was conducted on samples of 340 students at the Faculty of Nursing, Cairo University. Data were collected through demographic background information sheet and Social Networking Addiction Scale.

Results:

All the students were addicted as 6.76% were severely addicted and 60.59% and 32.65% were moderately and mildly addicted, respectively. Significant relations were found between social media addiction and students' age (χ
2 = 11.331, P = 0.003), educational level (χ
2 = 20.239, P = 0.003), and grade point average (χ
2 = 19.378, P = 0.013).

Conclusion:

Internet addiction was prevalent among all students but at different levels, so early screening of students for Internet addiction using the Internet Addiction Scale is important to provide early treatment and prevent hazards to health.
An analysis of association of personality traits with job burnout among nurses working in hospital
Authors: AKBARI Hossein , MOTALEBI KASHANI Masoud , DEHGHANI BIDGOLI Sedighe , NASRABADI Masoumeh Koochaki , KARAMALI Fahimeh
Published: September 2023

Objective:

The objective of the present study is to explore the effects of personality traits on job burnout among hospital nurses.

Materials and Methods:

This cross-sectional research was done during 2019–2020 at Kashan Shahid Beheshti Hospital. The data analysis procedures included descriptive statistics and the partial least squares-based structural equation modeling. The participants were 150 nursing professionals. A questionnaire indicating information on demographics, burnout (measured using the Maslach Burnout Inventory with three dimensions of depersonalization, emotional exhaustion, and personal accomplishment), and personality profile (measured employing the neuroticism extraversion openness five-factor inventory including extroversion, conscientiousness, agreeableness, neuroticism, and openness to experience dimensions) was used to gather the required data.

Results:

The results of the study showed that the validity and reliability of the measurement model were desirable (factor load higher than 0.5, the Cronbach's alpha value and the composite reliability are >0.7). Structural model showed statistically drastic, negative relationship between the nurses' burnout levels and neuroticism (β = −0.722) and openness to experience (β = −0.437). However, the relationship was significantly positive between the nurses' burnout levels and conscientiousness (β = 0.672), agreement (β = 0.594), and extraversion (β = 0.559) (P < 0.03).

Conclusions:

The present study helped the recognition of burnout among nurses working in hospitals and approved the effects of personality features on the burnout experience.
Psychiatric nursing
Authors: PANNEERSELVAM Suganya , RAMASAMY Senthilkumar
Published: September 2023

Health-care professionals acquire negative and discriminatory attitudes toward mental health. Psychiatric nursing is considered a less valuable field and they choose to work in a psychiatric setting only when there are no other employment opportunities. The global burden of disease study (2017) shows that 197.3 million people had mental disorders in India and one in seven Indians were affected by mental disorders. Extending the theory and clinical posting hours in psychiatry helps to promote a sense of preparedness and reducing the negative stereotypes can contribute to develop an interest in a future career in psychiatric nursing. Mental health is the foundation for the well-being and effective functioning of an individual. They play a plethora of roles such as case manager (clinical nurse), mentor, lecturer, researcher, policymaker, counselor, and clinical psychologist. Hence, it is the right time to choose this right field, which has a lot of opportunities.
The Effect of Risk Factors on the Clinical Course and Treatment of Older Patients with Coronavirus Disease 2019
Authors: Duzgun Ulkuhan , Sonkaya Ali Riza , Öztürk Bilgin , Sarı Oktay , Yurdakul Eray Serdar , Savaşçı Ümit , Doğan Deniz , Karadaş Ömer
Published: September 2023

Introduction:

Coronavirus disease 2019 (COVID-19) is known to have higher morbidity and mortality rates, parallel to the increased risk factors in the elderly. We aimed to define the risk factors related to mortality and morbidity in older patients hospitalized with COVID-19 disease in this study.

Materials and Methods:

This retrospective cross-sectional study included patients aged ≥65 years who were hospitalized with a confirmed diagnosis of COVID-19. We analyzed their demographic data, clinical findings, comorbidities, laboratory and radiologic findings, treatment protocols, and outcomes.

Results:

A total of 58 patients were included in the study. A total of eight (13.8%) patients died during the clinical follow-up and treatment, and 50 (86.2%) patients were discharged. The most common comorbidities among all patients were hypertension (HT) (69%) and diabetes mellitus (39.7%). The most common symptoms include fever (51.7%), cough (44.8%), and dyspnea (43.1%), and the most common neurologic findings were headache (27.6%) and impaired consciousness (27.6%). Intensive care unit admission was significantly higher among patients with comorbidities of HT, cerebrovascular disease, atrial fibrillation (AF), and chronic obstructive pulmonary disease. The rate of death was significantly higher in patients with a history of smoking, cerebrovascular disease, AF, and HT. Although there was a statistically significant positive correlation between the death rate and leukocyte, neutrophil, C-reactive protein, lactate dehydrogenase, D-dimer, interleukin-6, and procalcitonin levels, a negative correlation was observed in lymphocyte levels.

Conclusion:

Age-related comorbid conditions, especially HT, cerebrovascular disease, and AF, caused increased morbidity and mortality rates in older patients with COVID-19.
Evaluation of the Relationship between Epileptic Seizures and Type of Parenchymal Lesion in Patients with Cerebral Venous Thrombosis
Authors: Dinç Yasemin , Demir Aylin Bican , Bakar Mustafa , Bora İbrahim
Published: September 2023

Introduction:

Epileptic seizures occur in approximately 35%–40% of patients with cerebral venous thrombosis (CVT). The relationship between parenchymal lesions and epileptic seizures in CVT has been investigated, but the most associated types of parenchymal lesions have not been determined. This study, therefore, aimed to identify high-risk groups.

Methods:

A total of 159 patients were diagnosed as having CVT between 2015 and 2021 at our tertiary center. The risk factors for epileptic seizures after CVT were determined.

Results:

A total of 159 patients who were diagnosed with having CVT, 109 (68.5%) females and 50 (31.5%) males, were included in this study. The mean ages of the women and men were 41.20 ± 14.15 years and 43.60 ± 16.30 years, respectively. We found that superior sagittal sinus involvement (P = 0.019), sigmoid sinus involvement (P = 0.010), cortical vein involvement (P < 0.001), parenchymal lesion (P < 0.001), and the postpartum period (P = 0.003) increased the risk of epileptic seizures. When the significant variables associated with epileptic seizures in the patients were analyzed using binary logistic regression, the most significant variable was found to be the presence of parenchymal lesions.

Conclusion:

We found that the most significant variable for epileptic seizures after CVT was parenchymal lesions. Juxtacortical hemorrhages and nonhemorrhagic venous infarcts were the most common causes of epileptic seizures. CVT is a heterogeneous group of diseases caused by multiple aetiologies and may show ethnic and racial differences. For this reason, more precise information can be obtained with multi-center prospective studies in our population.
Periodic Legs Movements in Sleep Persisting after Positive Airway Pressure Titration is Significantly Associated with Cardiovascular Diseases
Authors: Mahmudova Aygul , Kurucu Hatice , Şenel Gulcin Benbir , Karadeniz Derya
Published: September 2023

Purpose:

Obstructive sleep apnea syndrome (OSAS) and periodic limb movement disorder in sleep (PLMS) are highly prevalent diseases of sleep and both are associated with a negative cardiovascular outcome. The purpose of this study was to investigate the presence of PLMS in patients with OSAS in positive airway pressure (PAP) titration and examine its relation to cardiovascular diseases.

Materials and Methods:

All patients who were diagnosed as having OSAS after one-night polysomnographic (PSG) recording during a 1-year period and were been treated successfully through PAP titration PSG were investigated retrospectively.

Results:

Out of 460 medical files investigated, 300 patients were included in the study (204 males, 68%) with a mean age of 54.2 ± 10.6 years. A comparison between patients with a PLMS index >15/h and PLMS index <15/h revealed that cardiac diseases (P = 0.040), hypertension (HT) (P = 0.006), and hyperlipidemia (P = 0.019) were all more common if patients had a PLMS index >15/h. Furthermore, a significant correlation was detected between the PLMS index and cardiac diseases (ß = 39.908, P = 0.012) and HT (ß = 32.884, P = 0.021).

Conclusions:

The risk of cardiovascular diseases is markedly increased in patients with OSAS with PLMS, and this was positively correlated with the PLMS index. Physicians should be aware that PLMS persisting after PAP titration might prevent the efficiency of PAP therapy in OSAS, especially in preventing cardiovascular complications.
The Relationship between Early Neurological Deterioration, Poor Clinical Outcome, and Venous Collateral Score in Cerebral Venous Sinus Thrombosis
Authors: Dinç Yasemin , Özpar Rıfat , Hakyemez Bahattin , Bakar Mustafa
Published: September 2023

Background and Purpose:

Cerebral venous sinus thrombosis (CVST) is one of the rare causes of cerebrovascular disease and has an extremely heterogeneous prognosis. The aim of this study was to investigate the potential relationship between early neurological deterioration, poor clinical outcome in CVST and the venous collateral score.

Materials and Methods:

A total of 121 patients diagnosed with CVST between 2010 and 2020 were retrospectively included. The demographic, clinical, and radiological findings related to venous sinus thrombosis and early neurological deterioration were investigated in relation to the clinical outcome.

Results:

The factors associated with early neurological deterioration were superior sagittal sinus thrombosis (P < 0.001), sinus rectus thrombosis (P = 0.031), parenchymal lesions (P < 0.001), and venous collateral score (P < 0.001). The factors associated with poor clinical outcome were superior sagittal sinus thrombosis (P < 0.001), cortical vein thrombosis (P < 0.001), venous collateral score (P < 0.001), and initial clinical symptoms. Binary logistic regression analyses revealed poor clinical outcome as a significant variable, with a venous collateral scale of 0 or 1 as a risk factor for a poor outcome (significance of the model P < 0.001).

Conclusion:

Early neurologic deterioration and poor clinical outcome may occur due to poor collateralization in CVST. Identifying the subgroup of CVST patients at risk of clinical deterioration is therefore important. This study highlights the clinical importance of venous collaterals; however, larger prospective multicenter studies are required to confirm the relationship with venous collaterals in patients with CVST.
The Effect of an Interactive Tele Rehabilitation Program on Balance in Older Individuals
Authors: Yerlikaya Tuba , Öniz Adile , Özgùren Murat
Published: September 2023

Objective:

To investigate the effect of a home-based interactive telerehabilitation program on balance performance in older people, and to compare the results with a nonsupervised home exercise (NHE) program.

Subjects and Methods:

A total of 50 participants (35 females), aged 65–90 years, were included in the study. The subjects were randomly assigned to one of three groups as the interactive telerehabilitation home exercise group (ITHE), NHE group or control group. The ITHE and NHE groups exercised three times per week for 8 weeks. The outcome measures were the Berg Functional Balance Scale (BBS), Timed Up and Go Test (TUG), Sway Balance Mobile Application, Trait Anxiety Inventory (TAI), and the World Health Organization Quality of Life Instrument-Older Adults Module (WHL).

Results:

In the control group, no difference was observed in the TUG and BBS scores, at the end of the 8 weeks compared with preexercise (pre-ex), whereas these scores increased significantly in the NHE (TUG: P < 0.001, BBS: P < 0.001) and ITHE groups (TUG: P < 0.001, BBS: P = 0.003). The WHL scores increased significantly in all three groups, and no difference was observed in the TAI scores. There was a significant difference in SWAY score only in the telerehabilitation group compared with pre-ex (P < 0.001).

Conclusions:

Although NHE and ITHE were effective on the improvement of balance, mobility and reduction of fall risk in older individuals, this effect was found to be greater in the ITHE group. Quality of life increased in all groups, but no change in anxiety level was observed.
A case of hepatic hydatid disease and imaging findings
Authors: Zhou Cong , Ju Hongge , Chen Qiang , Luo Lin
Published: September 2023

A 45-year-old female patient was admitted to our hospital due to a space-occupying lesion which was found in a physical examination. Slight tenderness was found in her right lower abdomen for 1 month. On computed tomography (CT) imaging, a round, low-density lesion was observed in the liver. Several round cysts with lower density and thin wall were scattered in the center of the lesion. Linear calcification could be found in partial cystic wall. No significant enhancement was found in the lesion on contrast-enhanced CT imaging. A laparotomy was performed to remove the mass, which was sent to a pathological examination and hepatic cystic echinococcosis was diagnosed.
Sepsis-associated encephalopathy
Authors: Zhong Yazhi , Cheng Yan , Wu Renhua
Published: September 2023

Sepsis-associated encephalopathy (SAE) is a serious complication of sepsis, which is caused by a dysregulated host response to infection. The high morbidity and mortality of SAE severely diminish the quality of life of the affected patients and families, and therefore, early diagnosis and treatment are essential. The pathogenesis of SAE is complex, involving neuroinflammation, impairment of blood–brain barrier function, neurotransmitter imbalance, and mitochondrial dysfunction. Imaging studies have provided insight into the neuropathological changes by traditional computed tomography and magnetic resonance scans, which reveal changes in brain structure and function in patients with advanced SAE. Currently, SAE is mainly diagnosed by the presence of typical clinical symptoms and by laboratory examination; however, accurate diagnosis in the early stage of SAE remains difficult. With the development of new imaging technologies, there has been an increase in imaging options for the early identification of SAE as well as for studies into the pathogenesis and pathophysiology of the disease. Here, we review the pathogenesis of SAE and the main neuroimaging findings. Furthermore, we suggest how to use the new imaging techniques for early identification and for research into the pathogenesis of SAE, which may help to enhance diagnosis and improve the prognosis of the disease.
RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer
Authors: Wang Xue-Jun , Liu Yong , Ke Bin , Zhang Li , Liang Han
Published: September 2023

Pancreatic cancer (PanCa) presents a catastrophic disease with poor overall survival at advanced stages, with immediate requirement of new and effective treatment options. Besides genetic mutations, epigenetic dysregulation of signaling pathway-associated enriched genes are considered as novel therapeutic target. Mechanisms beneath the deoxyribonucleic acid methylation and its utility in developing of epi-drugs in PanCa are under trails. Combinations of epigenetic medicines with conventional cytotoxic treatments or targeted therapy are promising options to improving the dismal response and survival rate of PanCa patients. Recent studies have identified potentially valid pathways that support the prediction that future PanCa clinical trials will include vigorous testing of epigenomic therapies. Epigenetics thus promises to generate a significant amount of new knowledge of biological and medical importance. Our review could identify various components of epigenetic mechanisms known to be involved in the initiation and development of pancreatic ductal adenocarcinoma and related precancerous lesions, and novel pharmacological strategies that target these components could potentially lead to breakthroughs. We aim to highlight the possibilities that exist and the potential therapeutic interventions.
Incorporation of perigastric tumor deposits into the TNM staging system for primary gastric cancer
Authors: Li Yang , Li Shuo , Liu Lu , Zhang Li-Yu , Wu Di , Xie Tian-Yu , Wang Xin-Xin
Published: September 2023

Pancreatic cancer (PanCa) presents a catastrophic disease with poor overall survival at advanced stages, with immediate requirement of new and effective treatment options. Besides genetic mutations, epigenetic dysregulation of signaling pathway-associated enriched genes are considered as novel therapeutic target. Mechanisms beneath the deoxyribonucleic acid methylation and its utility in developing of epi-drugs in PanCa are under trails. Combinations of epigenetic medicines with conventional cytotoxic treatments or targeted therapy are promising options to improving the dismal response and survival rate of PanCa patients. Recent studies have identified potentially valid pathways that support the prediction that future PanCa clinical trials will include vigorous testing of epigenomic therapies. Epigenetics thus promises to generate a significant amount of new knowledge of biological and medical importance. Our review could identify various components of epigenetic mechanisms known to be involved in the initiation and development of pancreatic ductal adenocarcinoma and related precancerous lesions, and novel pharmacological strategies that target these components could potentially lead to breakthroughs. We aim to highlight the possibilities that exist and the potential therapeutic interventions.
Multidisciplinary discussion and management of synchronous colorectal liver metastases: A single center study in China
Authors: Li Hao , Gu Guo-Li , Li Song-Yan , Yan Yang , Hu Shi-Dong , Fu Ze , Du Xiao-Hui
Published: September 2023

Pancreatic cancer (PanCa) presents a catastrophic disease with poor overall survival at advanced stages, with immediate requirement of new and effective treatment options. Besides genetic mutations, epigenetic dysregulation of signaling pathway-associated enriched genes are considered as novel therapeutic target. Mechanisms beneath the deoxyribonucleic acid methylation and its utility in developing of epi-drugs in PanCa are under trails. Combinations of epigenetic medicines with conventional cytotoxic treatments or targeted therapy are promising options to improving the dismal response and survival rate of PanCa patients. Recent studies have identified potentially valid pathways that support the prediction that future PanCa clinical trials will include vigorous testing of epigenomic therapies. Epigenetics thus promises to generate a significant amount of new knowledge of biological and medical importance. Our review could identify various components of epigenetic mechanisms known to be involved in the initiation and development of pancreatic ductal adenocarcinoma and related precancerous lesions, and novel pharmacological strategies that target these components could potentially lead to breakthroughs. We aim to highlight the possibilities that exist and the potential therapeutic interventions.
Correction to “Interleukin-34 promotes the proliferation and epithelial-mesenchymal transition of gastric cancer cells”
Authors: Li Chuan-Hong , Chen Zhang-Ming , Chen Pei-Feng , Meng Lei , Sui Wan-Nian , Ying Song-Cheng , Xu A-Man , Han Wen-Xiu
Published: September 2023

Pancreatic cancer (PanCa) presents a catastrophic disease with poor overall survival at advanced stages, with immediate requirement of new and effective treatment options. Besides genetic mutations, epigenetic dysregulation of signaling pathway-associated enriched genes are considered as novel therapeutic target. Mechanisms beneath the deoxyribonucleic acid methylation and its utility in developing of epi-drugs in PanCa are under trails. Combinations of epigenetic medicines with conventional cytotoxic treatments or targeted therapy are promising options to improving the dismal response and survival rate of PanCa patients. Recent studies have identified potentially valid pathways that support the prediction that future PanCa clinical trials will include vigorous testing of epigenomic therapies. Epigenetics thus promises to generate a significant amount of new knowledge of biological and medical importance. Our review could identify various components of epigenetic mechanisms known to be involved in the initiation and development of pancreatic ductal adenocarcinoma and related precancerous lesions, and novel pharmacological strategies that target these components could potentially lead to breakthroughs. We aim to highlight the possibilities that exist and the potential therapeutic interventions.
Weights, Tube Fitting, Estimating, Weighing and Maintaining, Procedure for
Authors:   G-3, Aerospace Couplings, Fittings, Hose, Tubing Assemblies
Published: September 2023

This SAE Aerospace Recommended Practice (ARP) establishes procedures for estimating the weight of parts, weighing actual parts at time of manufacture and maintaining and collecting the weight data.
DirKorp
Authors: Bago Petra , Karlić Virna
Published: September 2023

In this paper, we present recent developments on a new version (v3.0) of DirKorp (Korpus direktivnih govornih činova hrvatskoga jezika), the first Croatian corpus of directive speech acts developed for the purposes of pragmatic research. The corpus contains 800 elicited speech acts collected via an online questionnaire with role-playing tasks, a method of simulated communication that is implemented under pre-set conditions. This method is suitable for researching speech acts due to the ability to collect a great number of examples of such acts of equal propositional content and illocutionary purpose used in the same controlled situations. The presented situations are classified into two categories with regard to the relationship between the participants of the communication act: (1) situations involving interlocutors who are not in a familiar relationship; (2) situations involving interlocutors in a familiar relationship. Assignments of the two categories are organized into four pairs, asking respondents to share a speech act of similar propositional content. The respondents were 100 Croatian speakers, all undergraduate (63%) or graduate students (37%) of the Faculty of Humanities and Social Sciences (University of Zagreb). The corpus has been manually annotated on the speech act level, each speech act containing up to 14 features: (1) respondent ID, (2) familiarity/unfamiliarity, (3) utterance type, (4) directive performative verb in 1st person, (5) illocutionary force, (6) propositional content, (7) T/V form, (8) exhortative, (9) lexical marker of request, (10) lexical marker of apology, (11) lexical marker of gratitude, (12) honorific title, (13) grammatical mood, and (14) modal verb in 2nd person. It contains 12,676 tokens and 1,692 types. The corpus is encoded according to the TEI P5: Guidelines for Electronic Text Encoding and Interchange, developed and maintained by the Text Encoding Initiative Consortium (TEI). DirKorp is available for download under the CC BY-SA 4.0 license from GitHub in TEI format. We describe applied pragmatic annotation as well as the structure of the corpus.
Universal Dependencies za slovenščino
Authors: Dobrovoljc Kaja , Terčon Luka , Ljubešić Nikola
Published: September 2023

Universal Dependencies (UD) je mednarodno usklajena označevalna shema za medjezikovno primerljivo oblikoslovno in skladenjsko označevanje besedil po načelih odvisnostne slovnice, ki je bila ob več kot 130 drugih svetovnih jezikih uspešno uporabljena tudi za označevanje besedil v slovenščini. V prispevku predstavimo rezultate nedavnih aktivnosti v povezavi s shemo UD znotraj projekta Razvoj slovenščine v digitalnem okolju, v okviru katerega smo obstoječo infrastrukturo nadgradili s prenovo in podrobno dokumentacijo označevalnih smernic UD za slovenščino, razširitvijo drevesnice SSJ-UD za pisno slovenščino z novimi povedmi iz korpusov ssj500k in ELEXIS-WSD, izdelavo testne množice iz besedil korpusa SentiCoref za spletni portal SloBENCH ter polavtomatsko pretvorbo oblikoslovnih oznak referenčnih učnih korpusov SUK in Janes-Tag. Na razširjeni drevesnici SSJ-UD je bil naučen tudi novi napovedni model za skladenjsko razčlenjevanje v orodju CLASSLA-Stanza, ki ga v prispevku v podporo nadaljnjim jezikoslovnim aplikacijam podrobneje ovrednotimo z vidika splošne natančnosti razčlenjevanja in najpogostejših tipov napak.
Atlas of the butterflies and moths of Nigeria, LepiMap report, 2010–2021
Authors: Ringim Abubakar S. , Abubakar Haruna M. , Acha Eyos K. , Okpanachi Atabo L. , Rautenbach Fanie
Published: September 2023

Interest in citizen science, notably biodiversity mapping, has soared recently in Africa, owing to several converging factors. First, is the growing recognition that biodiversity is threatened, and second, there is a need for collective effort among the public to improve the state of biodiversity, driven by human activities. Amongst the important biodiversity components is Lepidoptera (butterflies and moths) which underpin crucial roles in the ecosystem. Although Lepidoptera has been a major field of study for the past decades, its ecology and distribution have only recently gained important attention among the public, particularly in West Africa. This paper reports on the number of butterflies and moths recorded for Nigeria on the LepiMap database. The database contains 1578 records from January 2010 up to August 2021, from 98 quarter-degree grid cells of the 1306 grid cells in Nigeria (7.5% of grid cells). There are 1219 recorded identified to species level (77%), with 359 awaiting identifications, mostly moths. The number of Lepidopterans recorded was 219 species belonging to 16 families. The most frequently recorded species were Catopsilia florella (28 grid cells, 64 records), Telchinia serena (27 grid cells, 61 records), and Danaus chrysippus alcippus (23 grid cells, 49 records). One of the most important successes of LepiMap during the last three years in Nigeria was the increase in the number of observers and coverage by 600%, which is crucial to gathering lepidopteran mapping data for conservation action. It is recommended that data collection be geared toward areas having no or low coverage, yet refreshing old records are also important for understanding changes in species composition across grid cells.
Iolaus freyaallanae sp. nov. (Papilionoidea: Lycaenidae: Theclinae) – a new species from Zambia in the genus Iolaus Hübner, [1819], subgenus Iolaphilus Stempffer & Bennett, 1958
Authors: Sáfián Szabolcs
Published: September 2023

A new species, Iolaus freyaallanae sp. nov. in the subgenus Iolaphilus Stempffer & Bennett, 1958 is described from forests in north-western Zambia. Its general appearance suggests, and examination of male and female genitalia confirms, a close relationship with I. gabunica Riley, 1928 and I. liberiana Sáfián, 2017. For easier navigation between them and other Iolaus species with similar facies, the I. gabunica species group is proposed.
Strategic Leadership Policy Strategies to Optimize Justice and Equity for Children of Child-Headed Households
Authors: Palmer June Monica , De Klerk Edwin Darrell , Esau Merlene Christobelle , Smit Elizabeth Ivy
Published: September 2023

Systemic inequalities pervade our education systems worldwide. No time, like the present, is more apt for school principals to thwart inequalities and ensure that quality is infused in all classrooms and permeates the entire schooling system. This article contributes to the paper on how school principals may utilize their strategic leadership role to enhance the socially just experiences of learners in child-headed households (CHHs). The aim is to investigate and counter justice and equity violations of learners in CHHs, from the perspective of social action leadership theory (SALT) with the help of deconstruction of texts in the Children’s Act, Policy on the South African Standard for Principals, and Revised White Paper on Families. The findings call attention to the human agency role of the principal to resist oppression in schools and promote equity and achieve justice and equity for learners in CHHs. Implications for a just strategic leadership plan to advance anti-oppressive practices for CHHs are shared. This article recommends that principals consider the recommended strategies to advance equity, enact human agency, and perform social justice to counter justice violations and prevent inequalities in school systems in their quest to realize equitable societies.
Enrolling Teenage Mothers in the Formal Secondary Education System: A New Policy Implementation Assessment
Authors: Issa Faisal Hassan , Temu Levina
Published: September 2023

This is an early assessment of a policy implemented to enroll teenage mothers in the formal secondary education system in Dar es Salaam, Tanzania. This important policy change allowing teenage mothers back to school is new. The actions taken are identified, and recommendations are made. The late Tanzanian President, Hon. John Pombe Magufuli, declared in a speech on June 22, 2017, that no pregnant students would be allowed to return to school during his presidency. However, after his untimely demise, a new head of state, a female president, changed the policy, and for the first time, directives were provided that teenage mothers should enroll back in schools.  In this research, a purposeful random sampling was used to select the required number of respondents. Questionnaires and interviews were utilized to gather primary data, while secondary data were collected from various earlier research and other sources. Data analysis employed descriptive statistics for quantitative data using MS Excel and qualitative data through content analysis. The study findings revealed that there is currently no legal framework or policy for enrolling teenage mothers in formal education. Teenage mothers struggle to balance school and parental responsibilities, and face discrimination from their peers.  To address these issues, the study recommends the development of a framework to guide formal education for teenage mothers, provision of financial resources, creation of a suitable learning environment, and moral support, including counselling.
Self-Awareness as a Key Emotional Intelligent Skill for Secondary School Principals’ Leadership Toolkit
Authors: Pretorius Anton , Plaatjies Bernadictus O'Brain
Published: September 2023

This study explores the importance of self-awareness as a fundamental emotional intelligence skill for the school principals’ leadership toolkit. Globally, school principals face complex challenges and responsibilities in the education system. Failure to manage these educational challenges effectively may result in failure as a principal. However, self-awareness as an emotional intelligence skill for school leadership demonstrates promising results in dealing with these difficulties. This qualitative study was conducted at six Motheo districts, Free State, South Africa secondary schools. Participants totaled 19, comprising six school principals, two deputy principals, three Heads of Departments (HODs), and eight teachers. The findings revealed that self-awareness as an emotional intelligence skill might have positive and significant results for school principals in managing and dealing with educational challenges and overall school leadership. The results indicated that self-awareness should be necessary for school principals. Improving the sub-skills of self-awareness, such as emotional awareness, self-regard, self-confidence, assertiveness, and independence, may give school principals the edge for school and principalship success. It is strongly recommended that principals and staff consider self-development and workshops or seminars on emotional intelligence, specifically self-awareness.
Os desafios da participação no âmbito do Sistema Nacional de Unidades de Conservação: Estudo de caso sobre o Conselho da Reserva Biológica do Gurupi, Maranhão, Brasil
Authors: Gonçalves de Souza Laís
Published: September 2023

O Sistema Nacional de Unidades de Conservação da Natureza prevê a criação de conselhos gestores para auxiliar na gestão das áreas protegidas. Apesar dessa garantia legal, isso não assegura que na prática haja uma participação efetiva da população. Assim, o objetivo deste artigo é discutir sobre o processo de constituição e funcionamento desses espaços, mediante o estudo de caso do conselho da Reserva Biológica do Gurupi, Maranhão, Brasil. Para tanto, analisamos as atas das reuniões desse conselho, realizadas entre 2012 e 2017. Os resultados dessa análise demonstram que após a criação do conselho as discussões acerca da reserva, antes restritas ao âmbito institucional, foram ampliadas. Todavia, constatamos que as diretrizes que regem o conselho, assim como as disputas que se estabelecem nesse espaço, impõem diversos limites à participação da população nos processos decisórios envolvendo seu funcionamento e atuação. A partir do exposto, concluímos que são necessárias mudanças para tornar o espaço do conselho mais participativo e democrático.
Un col·loqui poc conegut de Carles Ros
Authors: Martí Mestre Joaquim
Published: September 2023

This paper deals with the philological edition of a literary text by the 18th c. Valencian grammarian and poet Carles Ros i Hebrera, “Paper graciós, discursiu, enfàtic, alusiu i sentenciós per a desfresar-se de llaurador a les carnistoltes”. This text is part of a group of humorous “col∙loquis” which Ros wrote on the occasion of the carnival. This edition is important since this dialogue has not been recorded in any of the compilations and studies of Ros’ works so far, despite belonging to one of the most popular groups of his works. Moreover, it has lately been listed within the lost or impossible to find works by the famous Valencian author. Finally this edition of the text, which entails several variations when compared to the other editions, is different from those mentioned by the bibliographers. The paper also encloses a study on the importance of the literary and linguistic works by Carles Ros, as well as a philological and literary analysis of the text we are editing.Keywords: Literature, 18th century, València, Carles Ros.
Abús i empoderament: La dama de Reus, sis recreacions d'una cançó popular
Authors: Sunyer Magí
Published: September 2023

Summary: This article studies six contemporary re-creations of the folk song known – among other titles – as La dama de Reus or Capitel∙lo. The textual dialogue created by the rewriting reveals the respect that all the writers have for the elements of the plotand some of the formal features of the oral text. At the same time, all the writers manage to leave their own individual mark on the text, which depends on the period, their style and their own ideological interests. The article also analyses other recreations of the topic based on other cultured texts rather than on the folk song. From this basis, the article also discusses the myth and the legend in terms of the interest they awoke in the romantics and other subsequent writers.Keywords: re-writing, legend, myth, folk song.
Impacto de las Cooperativas de Ahorro y Crédito en la inclusión financiera: un análisis de su contribución a la evaluación social
Authors: Poveda Valverde Flor Ximena
Published: September 2023

La inclusión financiera, definida como la accesibilidad y disponibilidad de servicios financieros para todas las personas y empresas, es un aspecto crucial del desarrollo socioeconómico. Este estudio tiene como objetivo analizar el impacto de las Cooperativas de Ahorro y Crédito, también conocidas como Credit Unions, en la mejora de la inclusión financiera. Las Cooperativas de Ahorro y Crédito son instituciones financieras de propiedad de los miembros que priorizan servicios financieros basados en la comunidad. A través de una revisión exhaustiva de la literatura y un análisis empírico, este trabajo examina cómo las Cooperativas de Ahorro y Crédito han contribuido a ampliar el acceso a recursos financieros, fomentar hábitos de ahorro, facilitar el acceso al crédito y promover un sentido de propiedad y empoderamiento en comunidades marginadas. Como resultados se obtiene que la inclusión financiera es una meta global que tienen las cooperativas de Ahorro y Crédito y se concluye que mediante esta inclusión se llegará a fomentar sociedades más ecuánimes y empoderadas.
The Autofictional Ailing Self: Depression in Sylvia Plath’s The Bell Jar and Cella Serghi’s The Spider’s Web – A Comparison
Authors: Boev Hristo
Published: September 2023

During the COVID-19 pandemic and emerging from it many people went through depressive states, sometimes with a lethal outcome. Depression, however, can be caused by numerous factors not expressly necessitating a global cataclysm, invariably remaining a particular personal response to a perceived strong sensation of discomfort and loss of meaning in one’s life. This paper will examine the major novels by two writers – the American Sylvia Plath and the Romanian Cella Serghi with the purpose of comparing the autofictional representations of depression in both, paying attention to its causes, courses, and outcomes. The comparative analysis will also establish the power of autofiction as a phenomenon and its capacity of producing texts with interdisciplinary dimensions containing a universal appeal. By examining two autofictional responses to an identical issue – the modern disease occasioned by similar causes, the paper aims to provide potential solutions that might have worked to a healing effect in the other text with the potential to transcend the texts in question and be applied to real-life situations since the described incidents have already happened not once and not only as part of the lived experience of the two writers. Last but not least, by effectuating the comparison the article seeks to help promote an author from a smaller national literature to the realms of World Literature.