bluuebunny/crossref_metadata_2025 huggingface dataset:
Formulation of mouth-dissolving tablets containing a spray-dried solid dispersion of poorly water-soluble fenoprofen calcium dihydrate and its characterization
Authors: Narwariya Shailendra Singh , Jain Suman , Muthumanickam Alagusundaram
Published: May 2024

The aim and objective of this investigation focus on the formulation of mouth-dissolving tablets of Fenoprofen calcium dihydrate spray dried solid dispersions.
Materials and methods. Spray drying is a well-recognized manufacturing technique that can be used to create amorphous solid dispersions, which are an effective delivery method for poorly water-soluble pharmaceuticals such as Fenoprofen calcium dihydrate (FCD). In addition to skimmed milk powder (SMP) and FCD, the carrier β-cyclodextrin was used to produce solid dispersions.
Results and discussion. The production of solid dispersions yielded reproducible results. Solid dispersion with β-cyclodextrin and skimmed milk powder is one way to increase disintegration time by increasing the water solubility of inadequately water-soluble FCD. In-vitro dissolution experiments of FCD mouth-dissolving tablets revealed significant differences. Stability studies should evaluate drug product characteristics that are susceptible to change during storage and are anticipated to impact quality, safety, and efficacy to demonstrate that the optimal formulations remain stable over the course of the study. The results of stability experiments were statistically significant at p<0.05 using one-way ANOVA followed by Dunnet's test. During in-vivo anti-inflammatory experiments, the formulation SDC6 demonstrated a greater percentage of inhibition than the purified drug and super disintegrant, and the results were statistically significant using one-way ANOVA followed by the Bonferroni test.
Conclusions. The solid dispersions were prepared with β-cyclodextrin, and skimmed milk powder improved the solubility of the poorly water-soluble fenoprofen calcium dihydrate. In vitro dissolution experiments of fenoprofen calcium dihydrate mouth dissolving tablets and controlled tablets revealed significant differences
Content of macro- and microelements in rats with experimental autoimmune thyroiditis and under the influence of lemna minor
Authors: Kononenko Alevtyna , Kravchenko Vira
Published: May 2024

The aim was to study the effect of aqueous extract and 30 % alcohol tincture of Lemna minor frond (AELM and TLM) on the content of macro- and microelements in rats with experimental autoimmune thyroiditis.
Materials and methods. The effect of AELM and TLM was studied in a model of experimental autoimmune thyroiditis in rats, induced by immunization with human thyroid antigen. The serum levels of total thyroxine, total triiodothyronine, antibodies to thyroglobulin, antibodies to thyroperoxidase, and concentrations of macro- and microelements were studied.
Results. The development of experimental autoimmune thyroiditis led to a decrease in the content of total thyroxine and antibodies to thyroperoxidase in the blood serum, an increase in the content of antibodies to thyroglobulin and a decrease in the concentrations of sodium, chlorine, potassium phosphorus, zinc, copper, iron and magnesium. It was found that the use of AELM and TLM against the background of autoimmune thyroiditis led to the restoration of T4 and elemental balance in rats, which was manifested in an increase in the content of sodium, chlorine, phosphorus, magnesium, zinc, iron, copper and calcium in the blood serum. It was also shown that TLM had a more powerful effect on the normalisation of the content of such elements as chlorine, potassium, copper and zinc. The obtained effect of AELM and TLM on the content of macro- and microelements in the blood serum of animals with experimental AIT can be explained by their positive effect on the functional activity of the thyroid gland. The studied extract and tincture may also affect other physiological and biochemical processes due to the content of macro- and microelements and other biologically active substances, which requires further research.
Conclusions. Administration of AELM and TLM to rats with experimental AIT contributed to lowering the level of Anti-TG and restoring the thyroid and elemental status in the animals' blood serum. The obtained research data allow us to recommend AELM and TLM as a regulator of the elemental status of the body in case of changes in thyroid function
Biological indicators and commercial exploitation of main fish and river crayfish species of the Zaporizhzhia (Dnipro) reservoir
Authors: Marenkov Oleh , Nesterenko Oleh , Borovyk Ivan , Gamolin Andrey , Shmagailo Mykola , Kapshuk Natalia
Published: May 2024

Aim: To analyze and summarize the biological indicators of the main industrial fish and river crayfish species in the Zaporizhzhia (Dnipro) reservoir under conditions of fishery exploitation.
Methods: Biological analysis of fish was conducted according to classical methods in ichthyology, using the following parameters: standard and absolute body length, individual mass, gender, feeding coefficient. Crayfish, caught in fishing gear, underwent morphometric measurements to determine individual mass and gender. Biological sampling was carried out during the vegetation period of 2023 during both control and commercial fishing in the Zaporizhzhia (Dnipro) reservoir at three sites differing in hydrology and degree of anthropogenic impact.
Research results: According to the data from the Department of the State Agency of Reclamation and Fisheries Management in Dnipropetrovsk Oblast, during 2023, 140,504 tons of fish were caught in the Zaporizhzhia (Dnipro) reservoir, nearly 8 times less than in 2021. In 2021, 1078.25 tons of aquatic resources were caught, which is 8 % less than in 2020. Silver carp was the dominant fish species in 2022, accounting for 80.5 % of the total catch in the reservoir. Herbivorous fish species accounted for 5.4 % of the catch, roach - 3.3 %, bream - 2.3 %, perch - 2.0 %. Based on the conducted research, recommendations have been provided regarding the establishment of forecasts and limits for the extraction of aquatic resources from the Zaporizhzhia (Dnipro) reservoir for the year 2024.
Conclusions: The Zaporizhzhia (Dnipro) reservoir has potential for the development of fishing, fish farming, and aquaculture in the Prydniprovsky region. The research results suggest that limits can be set on the catch of certain fish species: bream- up to 210 tons, pike-perch - up to 42 tons, roach - up to 350 tons, and perch - up to 138 tons. However, the catch of silver carp, bleak, sprat, herbivorous fish, and sun-perch is recommended to be unrestricted. The forecasted catch of crayfish is within 1 ton. The catch of other aquatic resources should also be conducted within forecasted levels
Kinetic models of distribution and testing of epidemic diseases in an isolated contingent
Authors:   Belarusian State University, Chigarev Anatoly , Chigarev Vitaly ,   Belarusian National Technical University, Adzerikho Igor ,   Belarusian Medical Academy of Postgraduate Education
Published: May 2024

Generalization of the classical SIR model of infection propagation are considered. The generalization of the models is carried out in two directions: 1) accounting for testing (monitoring), which is carried out in practice in all countries, by expanding SIR model by including an observation model; 2) accounting for the lack of reliable information about the state of the population is modeled by random processes (randomization), the statistics of which are determined by Kalman–Bucy estimation algorithms. The resulting model is mathematically more correct and stable, which makes it possible to obtain more reliable estimates of infection processes. The estimation model obtained by extension is described by equations corresponding to the regularization method for solving incorrect problems. The resulting system of equations simultaneously with the state estimation allows us to find the estimation error. To assess the infection process, when the number of recovered and deceased people is generally small compared to the number of susceptible to infection and infected people, a model is used that generalizes the Lotka-Volterra model, the natural course of the epidemic process. On the basis of the obtained model, the solution of reference problems is considered. A solution is obtained for the optimal estimate and its error at the initial stage of infection, when it can be assumed that the observed number of infected people increases linearly as a function of time, and the estimation error at the initial time is large relative to the number of really infected people. Obtaining reliable observations is the basis for making effective decisions to combat the epidemic. The developed model reflects the uncertainty that exists in practice in assessing the level of the epidemic condition of the population. The reference problem is considered, when the estimate of the number of infected people is a function that varies with time, although in reality the number of infected people remains constant over time (stationary state). Thus, the model describes the effect of pseudo epidemic, which can exist in an amount with a constant total number of all groups.
Study of the double poling kinematics of elite cross-country skiers
Authors:   Novosibirsk State University, Kubyak Anna , Parshin Daniil ,   M.A. Lavrentev Institute of Hydrodynamics of the Siberian Branch of the Russian Academy of Sciences
Published: May 2024

Highly skilled cross-country skiers often prefer the double poling technique due to its speed and versatility. This work is aimed at developing a biomechanical model of a skier using the double poling technique. To do this, using video recordings of the competition, experimental data of eight elite-level athletes (four males and four females) were prepared and analyzed, who used the indicated technique while passing the distance. The analysis made it possible to determine the dependence of the angles in some joints on time, as well as to assess the repeatability of the double poling movement from cycle to cycle. As a result, the main control parameters were identified by which the skier regulates the pace of his movement along the track and the geometric characteristics important for modeling. Statistically significant differences in technique for male and female are shown (P < 0,01), which is extremely important in the development of personalized models of movement. The conclusions drawn will contribute to the correctness of the construction of a mathematical model of double poling biomechanics.
Re-analysis of a meta-analysis about tryptophan and depression
Authors: Plöderl Martin
Published: May 2024

This is a reanalysis of a meta-analysis about L-tryptophan blood levels and depression, which became part of the controversy around a recent umbrella review about the role of serotonin in depression. The reanalysis revealed major methodological limitations, raising doubts on the conclusions in the original publication that levels of tryptophan are lowered among depressed compared to non-depressed individuals. The data is also compatible with a null effect and no firm conclusion should be made.
APPLICATION OF BACTERIAL SOURDOUGH AND ENZYMES IN THE PRODUCTION OF BREAD FROM A MIXTURE OF RYE AND WHEAT FLOUR
Authors: Korzhenivska A. , Danylenko S. , Gunko S. , Kozlovska G. , Lukianets А.
Published: May 2024

Interest in sourdough rye-wheat bread with addition of enzymes is actively demonstrated by various manufacturers. Enzymes associated with the metabolic activity of sourdough microorganisms and exogenous enzymes deliberately added to the dough recipe are used in the production of these bakery products. Such combinations contribute to the improvement of both dough structure and the final product. The research investigated the influence of the combined application of the IPROVIT sourdough and enzymes α-amylase, glucoamylase and protease on the structural-mechanical properties of the dough and the quality of the resulting rye-wheat bread. Optimal concentrations of individual enzymes and their combinations were established: α-amylase – 0.35 mL, protease - 0.05 mL, glucoamylase - 3 mL, α-amylase+glucoamylase and α-amylase+protease in a 1:1 ratio. Adding enzymes at rational concentrations positively affected on the physical properties of the dough, making it elastic, shaping well into a ball and preventing spreading. Increased enzyme concentrations led to stickiness and eventual spreading of the dough. It was observed that the combined application of Lactobacillus plantarum, L. brevis, Lactobacillus paracasei ssp. paracasei bacteria and enzymatic preparations (α-amylase, protease, glucoamylase) of different actions positively affected the physical properties of the dough. The dough mixed well, did not stick to hands, maintained its shape, faster increased of volume and had moisture levels within the control range of 41–43%. The acidity of the resulting bread met the requirements of DSTU 4583:2005 and amounted to 8.9–10 degrees for all tested samples. Reduced acidity in the sample with the enzyme complex α-amylase+protease is explained by the fact that the amino acids formed as a result of the protease action were used by lactic acid bacteria as a source of nutrients. The combined application of lactic acid bacteria and enzymes positively contributed to intensifying fermentation processes, indicated by higher dough rising indicators, which were 3–9 min higher than the control. Through the use of enzymes with different actions, it was proven that the organoleptic characteristics of the bread improved, acquiring an attractive color, distinct taste and pleasant specific aroma with hints of nutmeg. The porosity of the experimental bread samples with the enzyme mixture was at the control level. Thus, the use of rye-wheat flour, sourdough and enzymes has a positive effect on the quality of bread and contributes to increasing its nutritional and biological value.
AVALIAÇÕES EXTERNAS NO MUNICÍPIO DO RIO DE JANEIRO E OS SENTIDOS NA BUSCA DE QUALIDADE DA EDUCAÇÃO
Authors: Oliveira Cristiane Gomes de , Moreira Carlos Roberto , Gomes Emerson Bezerra Vidal
Published: May 2024

Este artigo tematiza a Política de Avaliação da Secretária Municipal de Educação do Rio de Janeiro-SME, nos últimos vinte anos. Ao problematizar a influência das políticas educacionais sob o alinhamento das avaliações externas no Estado, traz-se ao foco de análise um discurso político hegemônico através do conceito da Governamentabilidade (Ball, 2014), forjando um regime de verdade em torno das avaliações de larga escala utilizadas como medição do sentido de qualidade da educação carioca. A discussão consiste no endereçamento de um sentido de qualidade da educação, determinado por agências econômicas internacionais (Organização para Cooperação do Desenvolvimento Econômico – OCDE, Banco Mundial, Fundo Monetário Internacional – FMI) através das avaliações externas. Estudos sobre globalização e redes de políticas de Stephen Ball atrelados a Michel Foucault, fundamentam a conjectura sobre demandas neoliberais presentes nas políticas curriculares da SME. Thomas Popkewitz (2016) aporta a problematização das políticas educacionais comprometidas com uma significação de qualidade da educação baseada na economia capitalista. A revisão teórica e análise de documentos oficiais deste artigo apresentam: o detalhamento das características e políticas da SME; a problematização das estatísticas como promotoras de regime de verdade, na perspectiva de “número mágico” que pauta discussões sobre as produções de políticas educacionais vigentes a partir dos resultados das avaliações externas; e a análise de cunho empírico político educacional da legitimação das avaliações externas no país. Destaca-se,por fim,a contribuição das agências internacionais para a difusão do ideário de um cidadão global forjado nas escolas na relação currículo-avaliação de larga escala-sentido de aprendizagem e neoliberalismo
POLÍTICAS DE CURRÍCULO PARA LÍNGUA PORTUGUESA
Authors: Costa Hugo Heleno Camilo , Cunha Érika Virgílio Rodrigues da , Rodrigues Maria José Vilela
Published: May 2024

O artigo põe em plano a noção de hegemonia, reconceptualizada por Laclau e Mouffe, defendendo que ela permite o entendimento de propostas prescritivas e universalistas na política curricular. Volta-se ao foco regulador da BNCC pondo em discussão as disputas por significação disparadas pela reiteração dos termos novos e multiletramentos na Língua Portuguesa nos Anos Finais do Ensino Fundamental. De início, é justificada a abordagem discursiva e uma segunda seção busca demarcar as noções de hegemonia, antagonismo e tradução. Na terceira seção são problematizadas as tentativas de significar os termos novos e multiletramentos na BNCC, des-sedimentando jogos discursivos pelos quais a regulação e o controle sobre o que é conhecimento e sujeito se insinuam como necessários. Conclusivamente, sinaliza-se para a leitura de que na política curricular para LP na BNCC são hegemonizados sentidos para novos e multiletramentos baseados na ficção de que seria possível antever um futuro (compreendido no contexto da proposta como incerto) e, então, preparar o sujeito. Pondera não bastar somente apontar para a assimetria de tal proposta em si, sendo importante tensionar a perspectiva de que é na relação com tais sentidos que a escola tende a ser tomada como deficitária e sem qualidade. Assim, defende-se que a BNCC para LP projeta a leitura de que a escola é deficitária e precisa ser reformada por um currículo nacional por ser incapaz de fazer o impossível: produzir hoje sujeitos para um futuro imprevisível.
COTIDIANO, EDUCAÇÃO E CULTURAS
Authors: Souza Dorisney Bastos de , Drummond Rosalva de Cássia Rita
Published: May 2024

O texto compreende uma resenha sobre o livro "Cotidiano, Educação e Culturas: realizações, tensões e novas perspectivas", organizado por Vera Maria Candau, que oferece contribuições valiosas sobre currículo, cotidiano e cultura. Reflete uma postura crítica frente à colonialidade e monoculturalidade na educação contemporânea, buscando promover uma sociedade mais justa e democrática. Dividido em quatro partes – "Cotidiano, Educação e Culturas (GECEC): articulando projetos e buscas", "Cosmologias, epistemologias, pedagogias e currículos 'outros'", "Decolonialidade, interculturalidade, branquitude e formação de educadores" e "Direitos humanos, cartografia social, culturas juvenis: sujeitos-saberes-fazeres insurgentes" – o livro compila reflexões instigantes para enriquecer o debate acadêmico.
Learning difficulties in school children: health and education professionals’ perceptions
Authors: Rumor Pamela Camila Fernandes , Durand Michelle Kuntz , Souza Jeane Barros de , Souza Janaina Medeiros de , Magagnin Adriana Bitencourt , Heidemann Ivonete Teresinha Schülter Buss
Published: May 2024

ABSTRACT Objectives: to understand health and education professionals’ perceptions regarding children’s learning difficulties in public schools. Methods: qualitative research, of the participatory action type, linked to Paulo Freire’s Research Itinerary. Forty-five professionals participated, through interviews and a Virtual Culture Circle. The analysis was developed through careful reading, reflection and interpretation of highlighted topics. Results: professionals discussed the (in)visibility of learning difficulties, strategies and resources in the educational sector and the search for solutions in the health sector. It was found that the production of complaints related to school learning is attributed predominantly as an individual problem of children or their family, exempting the educational institution from this process. Final Considerations: greater investment in professional training and development policies is urgently needed to facilitate coordination between sectors, with a view to overcoming outdated pedagogical and health models.
Pregnancy loss in women with systemic lupus erythematosus: Grounded Theory
Authors: Souza Rebeca Rosa de , Barreto Mayckel da Silva , Teston Elen Ferraz , Salci Maria Aparecida , Vieira Viviane Cazetta de Lima , Marcon Sonia Silva
Published: May 2024

ABSTRACT Objective: to learn the meanings attributed to pregnancy loss by women with Lupus. Method: qualitative research, based on Symbolic Interactionism and Grounded Theory. Data collection took place between January and August 2022 through in-depth interviews. Data analysis went through the stages of initial and focused coding. Results: seventeen women participated. The central phenomenon “The climb to motherhood: falls and overcoming” was constructed, consisting of three categories: “Falling to the ground during the climb: the experience of pregnancy loss”; “Getting up and following the path: new attempts to conceive”; and “Remembering the journey: meanings attributed to pregnancy losses”. Final considerations: experiencing pregnancy is, analogously, like climbing a mountain, where obstacles need to be overcome to reach the summit. The experience of pregnancy loss is seen as complex, especially when there is fragility in healthcare and a lack of awareness regarding feelings of loss and grief.
Satisfação do paciente com câncer sobre a qualidade da informação recebida: validação psicométrica do EORTC QLQ-INFO25
Authors: Bezerra Michele , Domenico Edvane Birelo Lopes De
Published: May 2024

RESUMO Objetivos: validar psicometricamente o instrumento da European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire EORTC QLQ-INFO25 e identificar os domínios que influenciam na percepção do paciente sobre as informações recebidas. Métodos: metodológico, transversal, com pacientes com câncer em instituição hospitalar filantrópica brasileira. Utilizaram-se instrumentos sociodemográficos e clínicos, EORTC QLQ-C30, EORTC QLQ-INFO25 e Supportive Care Needs Survey - Short Form 34. Análise ocorreu utilizando coeficientes alfa de Cronbach, correlação intraclasse, teste-reteste e análise fatorial exploratória. Resultados: participaram 128 respondentes. O coeficiente alfa de Cronbach foi de 0,85. O teste-reteste obteve p-valor=0,21. Na análise fatorial, foi excluído um item. A satisfação da informação recebida foi de 74%, com três domínios com médias inferiores a 70%. Nas questões abertas, evidenciou-se maior desejo por informações. Conclusões: evidências de validação foram obtidas com confiabilidade, consistência e estabilidade do instrumento. Os respondentes demonstraram satisfação com as informações recebidas.
Lycophytes and ferns of an Amazonian-Cerrado ecotone in Maranhão State, Northeastern Brazil: identification key and annotated list of taxa.
Authors: Silva Junior Wagner Ribeiro da , Prado Jefferson , Ferreira Alessandro Wagner Coelho , Fernandes Rozijane Santos , Oliveira Hermeson Cassiano de
Published: May 2024

Abstract We present a key to identify and an annotated list of lycophytes and ferns of the Immediate Geographical Region of São Luís, Maranhão State, which has ecotonal characteristics of Amazonian Forest, Cerrado, and Coastal Vegetation. Specimens were collected monthly between April 2020 and September 2022 in the 13 municipalities of this region. A total of 64 species were identified, including 61 species of ferns, in 18 families and 38 genera, and three species of lycophytes, in two genera and one family. The most representative families were Pteridaceae (18 species) and Polypodiaceae (nine species). The most recorded substrate of occurrence was terrestrial with 35 species (54.6%), followed by epiphytic with 15 species (23.4%), aquatic with four species (6.2%), rupicolous with three species (4.6%), and hemiepiphytic with two species (3.1%). Five species (7.8%) had more than one life form. This study expands the knowledge about the geographic distribution of fern and lycophyte species in the central region of Northern Maranhão, in Northeastern Brazil, which until now had several sampling gaps. Maranhão has a diversity that is still poorly reported and known compared to other states in South and Southeast Brazil. Therefore, floristic surveys are essential to increase what is known about the flora, especially in areas under anthropic pressure and places with few collections, such as the ecotonal areas in Maranhão.
Food preference of Phylloicus sp. (Insecta: Trichoptera): experimental study with plant species from the Cerrado
Authors: Almeida Vanessa Silva de , Brito Janaina Gomes de , Leite João Batista Araújo , Pereira Aline Alves , Brasil Leandro Schlemmer
Published: May 2024

Abstract The aquatic insects of the genus Phylloicus play a crucial role in aquatic ecosystems, shredding leaves and contributing to nutrient cycling in streams. Therefore, this genus is often used in laboratory experiments. However, in Cerrado regions such as Araguaia, these studies are impractical due to a lack of knowledge about basic aspects, such as their feeding preferences for local plants. Hence, our objective is to determine the native plant species in the Araguaia region preferred as food by Phylloicus. We conducted an experimental study comparing the consumption of three native Cerrado plant species: Casearia sylvestris, Astronium fraxinifolium, and Ficus guaranítica by Phylloicus. To assess differences in consumption, we performed an Analysis of Variance. The results revealed that Phylloicus larvae exhibited a feeding preference for Casearia sylvestris (F = 9.71; p = 0.004). This finding will contribute to the development of future experimental studies using Phylloicus in the Araguaia region, as understanding the feeding preferences of animals used in experiments is essential for their maintenance in the laboratory.
Serum profile of the anti-müllerian hormone of Nelore bulls in the peripuberty
Authors: Pereira J.A. , Satrapa R.A. , Gomes M.G.T. , Moure V.R. , Valdameri G. , Kozicki L.E. , Sousa G.C. , Souza F.F. , Laskoski L.M. , Souza F.A.
Published: May 2024

ABSTRACT This study aimed to investigate the profile of AMH serum concentrations during the period of prepuberty in young bulls. The bulls were selected and evaluated for 150 days to assess their sexual development. The semen and blood collection, body weight (kg), and scrotal measurements were performed every 30 days, and puberty (D0) was considered when at least 50×106 spermatozoa/mL, and 10% of progressive motility were verified for the first time. After the blood collection, plasma was separated and used to determine the AMH concentration by ELISA, presenting values of 611.4a (±94.5), 555a (±181.99), 621.6ab (±133.44), 370.4ab (±59.36) and 51.7b (±7.94) for moments of -60, -30, 0, +30 and +60 of puberty, respectively. During the evaluated period, there was a progressive increase in body weight (kg), scrotal circumference (cm), and semen characteristics. The AMH mean plasma concentration decreased 60 days after puberty onset. There was no correlation with the andrological parameters analyzed; however, there was a positive and strong correlation between the testicular height and width at puberty onset with plasma concentrations of AMH. We concluded that AMH is not a helpful tool for the early prediction of puberty in Nelore bulls.
Strobilocercus fasciolaris (Eucestoda: Taeniidae) in black rats (Rattus rattus) at Fernando de Noronha Island, Brazil
Authors: Lima D.C.V. , Pedrosa C.M. , Melo R.P.B. , Almeida J.C. , Magalhães F.J.R. , Morais E.G.F. , Lima Filho C.D.F. , Mota R.A.
Published: May 2024

ABSTRACT The island of Fernando de Noronha, belonging to the state of Pernambuco, Brazil, has several animal species introduced by man, such as the black rat (Rattus rattus) and the domestic cat (Felis catus), representing a risk to the ecological balance of the island and to the public health. This study aimed to report the occurrence of Strobilocercus fasciolaris in black rats (R. rattus) in this insular environment and to contribute with epidemiological data on this parasitosis. Rodents were captured using Tomahawk traps and sedated with an association of Ketamine Hydrochloride (40mg/kg/IM) and Xylazine Hydrochloride (2mg/kg/IM) for subsequent euthanasia and necroscopic evaluation. Of the 154 captured black rats, 54 (35.06%) had single or multiple cysts in the liver. The cysts were morphologically evaluated and the metacestodes were identified as Strobilocercus fasciolaris, the larval form of Hydatigera taeniformis. This is the first report of the occurrence of Strobilocercus fasciolaris in black rats (Rattus rattus) in an island environment in Brazil. The occurrence of this metacestode in rodents on the Island demonstrates the high environmental contamination, fast reproduction, and dispersion of this parasite, being a potential risk for the conservation of susceptible species and for public health.
Does the collective manual press change Minas Artisanal Cheese characteristics from Campo das Vertentes region?
Authors: Sobral D. , Costa R.G.B. , Moreira G.M.M. , Teodoro V.A.M. , Paula J.C.J. , Costa Júnior L.C.G. , Gomes M.S. , Nascimento T.A.G. , Pinto M.S. , Miguel E.M.
Published: May 2024

ABSTRACT The production of Minas Artesanal Cheese (MAC) is a centuries-old activity that involves a great deal of physical effort on the part of the producer, especially during the pressing stage, which is carried out by hand. Inspection agencies do not allow manual stainless-steel presses in MAC production. Studies are still needed to prove whether this technique changes the cheese characteristics. Therefore, this study tested two types of MAC production in the Campo das Vertentes region: traditional hand pressing and a new technology, a stainless-steel press. After the cheeses were made, analyses of their physicochemical composition and microbiological analysis were made, as well as their texture profile and instrumental color, over four ripening periods (7, 14, 22, and 30 days) to see if the pressing interfered with the characteristics of the MAC from the Campo das Vertentes-MG region. Pressing in a stainless-steel press did not change the main characteristics of the MAC studied, with changes only observed in some texture profile attributes. Therefore, a stainless-steel press is recommended in manufacturing and pressing MAC due to the health benefits for producers.
Sporotrichosis in guinea pig (Cavia porcellus) - case report]
Authors: Prazeres Júnior F.R. , Moreira A.C. , Medeiros N.O. , Carmo M.C.C. , Lima M.P.S.
Published: May 2024

ABSTRACT The guinea pig is a South American rodent with a docile behavior that has been gaining popularity as a pet, increasing the search for specialized veterinary care for the species. In the clinical casuistry, about half of the visits are due to dermatological changes, among which fungal infections are uncommon. Sporotrichosis is a zoonosis caused by the fungus of the genus Sporothrix, widely distributed in nature, which contaminates the host from the inoculation of the agent in lesions and mucous membranes and has been reported in several species of animals. Felines with access to the street are the main disseminators of the agent due to the behaviors of the species and can contaminate other animals and humans. The most evident clinical signs are crusted, exudative and difficult to heal lesions, requiring complementary tests such as PCR and culture to confirm the diagnosis. The specific treatment is time-consuming, using antifungal drugs such as itraconazole, which can be associated with topical treatment to aid healing. Given the difficulty of finding references about this zoonosis, it is difficult to obtain reliable data on the epidemiology of this disease. The present work describes the first report of sporotrichosis in guinea pig in Brazil, the complementary examinations that resulted in the definitive diagnosis and the effective therapeutic response, to contribute to possible work and research.
BRS Paiaguás and BRS Piatã: potential for use under water regimes in a semi-arid environment
Authors: Maranhão S.R. , Pompeu R.C.F.F. , Souza H.A. , Cândido M.J.D. , Fontinele R.G. , Lopes M.N. , Cavalcante A.C.R. , Rogério M.C.P. , Guedes F.L.
Published: May 2024

ABSTRACT This work aimed to evaluate the physiological parameters, the biomass flow, and the productive characteristics of the grasses BRS Piatã and BRS Paiaguás at different levels of water supply in the semi-arid region. The experiment was carried out in the dry season, in Sobral, Ceará State, Brazil. The following irrigation depths were used: 30, 60, 90, and 120% of ETo. The experiment was carried out in pots with a capacity of 7.5 dm3 at field level, using a 0-0.2m layer of argisol soil as substrate. As a result, the photosynthetic rate was not affected in the largest water treatments. In the biomass flow, the responses of grasses to treatments 90 and 120% of ETo were similar for the variables number of live leaves and phyllochron. Regarding the productive characteristics, pseudo-culm biomass was effective only in the treatment of 120% of ETo, while, for the efficiency of water use, in treatments 60 and 90% of ETo, the difference was effective. In conclusion, in the treatments of 60 and 90% of the ETo, it was possible to maintain good morphological characteristics of the grasses and to increase the biomass production during the dry season in the semi-arid region.
Comparative analysis of stress responses in dogs and cats during the covid-19 pandemic: a focus on cortisol, total leukocytes, eosinophils, and behavioral changes
Authors: Malancus R.N. , Arsenoaia V.N. , Ghita M.
Published: May 2024

ABSTRACT The COVID-19 pandemic has ushered in unprecedented changes in the lives of humans and their companion animals, impacting their daily routines, social interactions, and stress levels. This study investigates the effect of pandemic-related restrictions, including limited time outside and changes in owner habits, on the stress indicators of 34 dogs and 29 cats. Cortisol levels, total leukocyte counts, eosinophil counts, and behavioral changes have been analyzed to assess how these species are differentially affected by the altered environment and human interactions during the pandemic. The study revealed important behavioral changes in cats while the biochemical and hematological parameters were considerably affected in dogs. Our findings shed light on the unique stress experiences of dogs and cats and underscore the importance of considering individualized strategies for managing their well-being during extraordinary circumstances.
Bioactive Synthesis of Silver Nanoparticles Using Leaf Extract of Indigofera oblongifolia; Characterization, Antimalaria Activities
Authors: Murshed M. , Aljawdah H.M.A. , Mares M.M. , Al-Quraishy S.
Published: May 2024

ABSTRACT The use of biosynthesized nanoparticles is one of the broad research areas where silver nanoparticles (AgNPs) have anti-parasitic disease properties. The biological synthesis of silver (AgNPs) nanoparticles using methanolic extracts of the Indigofera oblongifolia leaf was evaluated. Gas chromatography-mass spectrometry (GC-MS) analysis, total of phenolics, and flavonoids, and MTT assay were used. In addition, UV-visible spectrophotometry, and TEM analysis. produced was stable and simple-to-synthesize AgNPs by UV light radiation. Classes of compounds expected to be biologically active were identified in the extract. Also, Quantitative results showed phenolics and flavonoids at 219 ± 1.079, and 19 ± 0.150 (mg TAE/g DW), respectively. Moreover, IC50 was obtained at 151.569 ± 8.5 ng/mL for Hep-G2 cell lines. Examination of IOLEAgNPs using transmission electron microscopy (TEM) showed that the nanoparticles were spherical with a smooth surface, which indicates that the prepared nanostructure content is highly pure with good morphology. Silver nanoparticles synthesized using leaf extract (AgNPs-leaf) were characterized by UV-visible spectrophotometry. Its activities have been tested as anti-malaria. OILEAgNPs were able to reduce parasitemia.
Application of the infant and young child feeding index and the evaluation of its relationship with nutritional status in 6-24 months children
Authors: Çelik Menşure Nur , Köksal Eda
Published: May 2024

ABSTRACT Objective To evaluate the complementary feeding practices of mothers in infant and child nutrition using Infant and Young Child Feeding Indicator and Infant and Child Feeding Index and to determine their relationship with nutritional status. Methods Study data were collected through an online questionnaire administered to 141 parents on healthy 6-24 month infants/children. Complementary feeding practices for infants/children were evaluated in line with the Infant and Child Feeding Index and Infant and Young Child Feeding Indicator. In the evaluation of growth, weight for age z-scores, length for age z-scores, and weight for length z-scores of infants/children were calculated with the World Health Organization Anthro program. Results 74.5% of 141 infants and children (71 boys, 70 girls) evaluated in the study are breastfed. The prevalence of stunting, wasted, and underweight was determined as 6.4%, 0.7%, and 4.3%, respectively. When evaluated using Infant and Young Child Feeding Indicator, it was determined that 82.3% of children met the minimum meal frequency, 80.9% met the minimum dietary diversity, and 67.4% met the minimum acceptable diet. Regarding Infant and Child Feeding Index evaluations of the children, while there was no difference between 9-11 and 12-24 month age groups, the mean Infant and Child Feeding Index score in the 6-8 month group was significantly lower than the other age groups (p=0.000). The Infant and Child Feeding Index scores used to evaluate complementary feeding practices in our study were found to be high in most infants/children. No clear relationship was found between stunting and minimum acceptable diet, minimum dietary diversity or minimum meal frequency, which are indicators of both Infant and Child Feeding Index scores and World Health Organization, Infant and Young Child Feeding Indicator. Conclusion The Infant and Child Feeding Index scores used to evaluate complementary feeding practices in our study were high in most infants/children. In addition, the high rates of MMF, minimum dietary diversity, and minimum acceptable diet coverage in evaluating infants/children in terms of World Health Organization indicators show that they have appropriate complementary feeding practices. However, study found no clear relationship between stunting and minimum acceptable diet, minimum dietary diversity or MMF, which are indicators of both Infant and Child Feeding Index I scores and WHO Infant and Young Child Feeding Indicator. It was concluded that World Health Organization Infant and Young Child Feeding Indicator indicators may be better than length for age z-scores in the weight for length z-scores explanation.
Prevalence and factors associated with food insecurity in quilombola families from Alagoas, Brazil.
Authors: Duarte Luisa Elvira Cavazzani , Santos Tamara Rodrigues dos , Santos Ewerton Amorim dos , Silva-Ferreira Haroldo da
Published: May 2024

ABSTRACT Objective This study aimed identify the prevalence and factors associated with food insecurity in families from the remaining quilombola communities in Alagoas, Brazil. Methods This is a cross-sectional study involving families residing in a random sample of 34 out of the 68 quilombola communities in Alagoas. The dependent variable was food insecurity, defined by the Brazilian Food Insecurity Scale, and its association (prevalence ratio - PR and 95% CI) with the independent variables (socioeconomic, demographic, and environmental) was assessed through multivariable analysis (Poisson regression with robust variance adjustment). Results A total of 2,485 families were evaluated, of which 67.6% were experiencing food insecurity (32.9% mild, 20.1% moderate, and 14.6% severe). Variables associated with moderate + severe forms were: improper waste disposal other than public collection; households with ≤4 rooms; using inadequate water for consumption; households with >4 residents; with residents <18 years old; low educational level of the head of the family (≤8 years); belonging to the lower economic class (D-E); and being a beneficiary of the Bolsa Família Program. Conclusion Food insecurity affects more than two-thirds of quilombola families in Alagoas, constituting an expressive public health problem. In its more severe forms (moderate+severe), it is associated with worse environmental, socioeconomic, and demographic conditions.
Who are the Solidarity Kitchen users? Study on inequalities to ensure food and nutritional security based on the experience of Sol Nascente community - Distrito Federal, Brazil
Authors: Madruga Samanta Winck , Machado Beatriz Oliveira Blackman , Oliveira Anelise Rizzolo de
Published: May 2024

ABSTRACT Objective To review the demographic and socioeconomic profile of the Homeless Workers Movement’s Solidarity Kitchen project users in the Sol Nascente Community, Federal District, Brazil. Methods Descriptive cross-sectional study. The interviews were conducted with adults, users of the solidarity kitchen, in August 2022, using a standardized questionnaire containing demographic, socioeconomic, housing and food consumption information. The outcome of the study was Frequent Use (picking up food at the solidarity kitchen five days/week). General and gender descriptive analyses were conducted, as well as a bivariate analysis based on the chi-square test (p<0.05). Results The sample was composed of 83 dark complexion women with a mean age of 39.6 years (SD=14.6). A total of 35 women (42.2%) had attended the first year of high school or over, and approximately 65.0% had a job and were paid up to one minimum wage. Most received social benefits and 81.9% were unemployed at the time of the survey. More than half of the respondents owned their own home and among those who did not, 64.0% paid rent. A total of 46.3% respondents had up to two daily meals. The prevalence of users who were considered Frequent Users was 61.0%. Women reported lower family income, greater dependence on aid, more unemployment, in addition to living with a greater number of people and having more people in the house who took food from the solidarity kitchen, all statistically significant differences. Conclusion The project Solidarity Kitchen essentially caters to dark complexion women with lower family income, who enhance the inequalities and inequities conditions in food security in the country.
CUIDADO DE ENFERMAGEM HUMANIZADO EM TERAPIA INTENSIVA EM ANGOLA: FACILIDADES E DIFICULDADES DESVELADAS
Authors: Sili Eurico Mateus , Nascimento Eliane Regina Pereira do , Malfussi Luciana Bihain Hagemann de , Vieira Patrícia Madalena , Lazzari Daniele Delacanal , Forster Fernanda , Lohn Arilene
Published: May 2024

RESUMO Objetivo: descrever as facilidades e dificuldades dos profissionais de enfermagem no cuidado humanizado em terapia intensiva em Angola. Método: pesquisa descritiva, qualitativa, realizada em Unidade de Terapia Intensiva de um hospital geral de Huambo, Angola, África, com 15 profissionais de enfermagem, no ano de 2020, por meio de entrevista semiestruturada. Utilizou-se o Discurso do Sujeito Coletivo para análise dos dados; e para a organização, o software QualiquantiSoft. Resultados: emergiram dos depoimentos cinco ideias centrais: duas envolvendo as facilidades; e três, as dificuldades em oferecer um cuidado humanizado. As facilidades referem-se ao envolvimento da equipe multiprofissional no cuidado e às relações interpessoais da equipe de enfermagem. As dificuldades estão atreladas à falta de recursos materiais, equipamentos e insumos; recursos humanos escassos e pouco preparo especializado da equipe de enfermagem. Conclusão: na humanização dos cuidados de enfermagem, as facilidades estão relacionadas ao comportamento e relações profissionais, enquanto as dificuldades, na sua maioria, envolvem aspectos de gestão que não estão sob a governabilidade dos profissionais, requerendo atenção dos gestores da instituição.
FATORES PREDITORES DE HOSPITALIZAÇÃO E ÓBITO EM IDOSOS COM COMPROMETIMENTO COGNITIVO: UM ESTUDO LONGITUDINAL
Authors: Barros Regina de Souza , Teixeira Gabriel Tourino Mafra , Pinto Juliana Martins , Sampaio Raphaela Xavier , Mendes Felipe Augusto dos Santos , Garcia Patrícia Azevedo
Published: May 2024

RESUMO Objetivo: identificar fatores sociodemográficos, condições clínicas e parâmetros de sarcopenia preditores de hospitalização e óbito em idosos com comprometimento cognitivo. Método: estudo observacional longitudinal realizado com 170 idosos com comprometimento cognitivo avaliados entre 2019 e 2021. As variáveis preditoras foram características sociodemográficas, condições clínicas e parâmetros de sarcopenia. A sarcopenia foi operacionalizada por meio da força muscular de preensão palmar (dinamometria), da massa muscular (circunferência da panturrilha) e do teste Timed Up and Go. A ocorrência de hospitalização e óbito até um ano após a avaliação do idoso configuraram as variáveis preditas. Procedeu-se análises por estatística descritiva, testes t-student independente, U Mann Whitney, Qui-Quadrado e de regressão logística univariada. Resultados: a maioria dos participantes era do sexo feminino (±77,57 anos), de baixa escolaridade, sedentários, 15,9% com sarcopenia e 13% com histórico de internação. Foi identificado que o nível de escolaridade teve efeito sobre a ocorrência de hospitalização (U=1423,5, p=0,027) e de óbito (U=647,0, p=0,025) no seguimento de um ano. Além disso, há associação do histórico de internação nos últimos 6 meses com a ocorrência de hospitalização [χ2(1)=4,729; p=0,030] e de óbito [χ2(1)=3,919; p=0,048] no seguimento de um ano. Identificou-se que o histórico de internação nos últimos 6 meses associou-se com a ocorrência de hospitalização em um ano de seguimento (OR=2,963; IC95% 1,076-8,165, p=0,036). Conclusão: o histórico de internação nos últimos seis meses está associado à ocorrência de hospitalização ao longo de um ano em idosos com comprometimento cognitivo.
Pessoa com Deficiência Intelectual e o Ambiente de Trabalho
Authors: Silva Margaret da Conceição , Mietto Gabriela Sousa de Melo , Chariglione Isabelle Patriciá Freitas Soares
Published: May 2024

RESUMO: O objetivo deste estudo foi identificar a compreensão das pessoas com deficiência intelectual sobre o ambiente de trabalho. A pesquisa foi realizada na perspectiva da psicologia histórico-cultural, em uma metodologia qualitativa, com participação de quatro pessoas com deficiência intelectual, maiores de 18 anos, por meio de entrevistas semiestruturadas de perspectiva narrativa. Os resultados indicaram que o conceito complexo Inclusão no Mercado de Trabalho foi formado por sete temas iniciais (sentido do trabalho; relações interpessoais; facilidades no trabalho; dificuldades no trabalho; autopercepção – significado da deficiência intelectual; percepção do outro em relação à pessoa com deficiência intelectual; e perspectivas laborais), que, por sua vez, foram organizados em cinco temas complexos (sentido do trabalho, relações interpessoais, políticas públicas, barreiras atitudinais e perspectivas laborais). A análise da formação conceitual indica que as narrativas apresentaram diversas conotações sobre a inclusão no ambiente de trabalho, sendo um importante espaço de desenvolvimento humano. Concluiu-se que a implementação de estudos com vistas à compreensão da inclusão no mercado de trabalho torna-se relevante para a compreensão do desenvolvimento humano e para a implementação e o planejamento de políticas públicas de inclusão.