bluuebunny/crossref_metadata_2025 huggingface dataset:
Water consumption forecasting models – a case study in Trinidad (Trinidad and Tobago)
Authors: Rajballie Aruna , Tripathi Vrijesh , Chinchamee Amarnath
Published: March 2022

Trinidad has undergone rapid urbanization over the past few decades. Urbanization is accompanied with an increase in the country's demand for water. The forecasting of water demand can give rise to a better understanding of water consumption behaviour across all sectors of economy and therefore aid in effective water demand management. This study compares the application of the seasonal ARIMA, exponential state space (ETS) models, artificial neural network (ANN) models and hybrid combinations of them in developing forecast models for all categories of water consumption for Trinidad. The best forecasting model was selected using the forecasting assessment criterion of Root Mean Square Error (RMSE), Mean Absolute Error (MAE) and Mean Absolute Percentage Error (MAPE). The forecasts were conducted until the end of December 2021. The results of the study show that hybrid model combinations are adequate in forecasting four out of the five categories and the single model, SARIMA, has been found suitable for the domestic category. Forecast plots revealed an increase in water demand until the end of 2021. The study also demonstrates the suitability of hybrid models for forecasting water demand for the island of Trinidad.
Objectively Measured Physical Activity Levels and Associated Factors in Older US Women During the COVID-19 Pandemic: A Quantitative Cross‐sectional Study (Preprint)
Authors: Choudhury Renoa , Park Joon-Hyuk , Thiamwong Ladda , Xie Rui , Stout Jeffrey R.
Published: March 2022

BACKGROUND

Physical activity (PA) is vital for attenuating the aging-related physiological and functional declines in women aged 60 years or above. However, little is known about the objectively assessed PA behavior in older women during the COVID-19 pandemic and its association with socio-demographics, health and physical function.

OBJECTIVE

This study aims to examine the objectively measured PA levels and associated factors among older US women, who were living under the physical distancing guidelines during the second year of the pandemic.

METHODS

In this cross-sectional study, we collected free-living PA data from 94 community-dwelling older women aged between 60 and 96 years (mean 75.1 years, SD 7.3 years) using wrist-worn ActiGraph GT9X accelerometers between February 2021 and August 2021. We examined if their daily duration spent in sedentary behavior (SB), light-intensity PA (LPA), and moderate-to-vigorous-intensity PA (MVPA) varied by sociodemographic characteristics, health and physical function, and COVID-19 related factors.

RESULTS

On average, participants accumulated 12.4 (SD=1.9) hours/day in SB, 218.6 (SD=64.3) min/day in LPA and 42.4 (SD=31.0) min/day in MVPA - exhibiting overall reduced PA levels than previously published pre-COVID norms of older women. Among participants aged≥80 years, sedentary time was 7.5% (P=.003) higher, and time spent in LPA and MVPA was, respectively, 13.3% (P=.03) and 44.9% (P<.001) lower than those aged 60-79 years. More MVPA participation and less sedentary lifestyle was observed in those who had higher self-rated health score (MVPA: P=.001, SB: P=.04) and lower fear of falling (FOF) (MVPA: P=.003, SB: P=.04). Poorer performance in 30-second sit-to-stand (STS) test was independently associated with more SB (P=.001) and less LPA (P=.011) and MVPA (P=.002) time among participants. Also, living alone was independently associated with less MVPA participation (P=.03). In addition, sedentary time was 5.0% higher (P=.03) in frail and prefrail participants than their healthy counterparts.

CONCLUSIONS

During the pandemic, older women spent the majority of their waking time being sedentary, while LPA accounted for a larger portion of their daily PA. Therefore, replacing SB with LPA (rather than MVPA) might provide a more feasible PA target for older women, particularly those aged≥80 years and who have reduced physical function. Also, targeted interventions might be beneficial in promoting an active lifestyle for those who live alone, are pre-frail or frail, and have high FOF in older age.

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/27381
Historia de las organizaciones pesqueras en la cuenca del lago de Pátzcuaro, Michoacán, 1930-2020
Authors: Contreras Jaimes Belinda , Camou Guerrero Andrés , Ayala Orozco Bárbara , Urquijo Torres Pedro Sergio
Published: March 2022

Objetivo: analizar el efecto de las políticas públicas en la configuración de las formas organizativas de la pesca en el lago de Pátzcuaro de 1930 a 2020. Metodología: investigación histórica mediante revisión documental de fuentes primarias, cotejadas con información estadística, y entrevistas estructuradas a los actores sociales clave. Resultados: la intervención sostenida del Estado mexicano ha derivado en una fragmentación social, expresada en diversas formas de organización de los pescadores que hoy proyectan ruptura, pero también reivindicación comunitaria. Valor: el trabajo subraya la importancia de una aproximación de análisis histórico a escala regional en materia de gestión pesquera. Limitaciones: la investigación requiere un enfoque participativo para el análisis de las formas organizativas vigentes. Conclusiones: para la gestión colaborativa de la pesca, es necesario considerar la heterogeneidad del grupo de los pescadores, además del análisis de la interacción entre fuerzas exógenas y endógenas a las localidades pesqueras.
Medios de tutela precontractual en el contrato de seguro
Authors: Vásquez Palma María Fernanda
Published: March 2022

The bases and foundations of the pre-contractual duties established in the Chilean legislation regarding insurance contract, connecting them with the structural weaknesses of the adhesion contract and contractual freedom as the cornerstone of every contract. We will see why the legislator adopts certain safeguards in this matter and how this has been related to the contractual balance. In our opinion, what is sought is to protect the real will of the parties, which can normally be seen in the reasonableness of the contractual stipulations. Along these lines, we will analyze the construction of the pre-contractual duties of the parties (insurer and insured), in contrast to the normative stipulations contained in the laws taken into account when enacting Law Nº 20.667, as well as the means of protection outlined for the protection of the creditor. In other words, we will refer to what is protected, when and how, and if there is a right to choose between the different paths offered. This exercise is necessary for an adequate interpretation of these precepts and their possible modification of lege ferenda.
IMPLEMENTASI PRINSIP KERJA 5S UNTUK MENINGKATKAN EFISIENSI WAKTU PRODUKSI STUDI KASUS DI SECTION INJECTION DI PT HBR
Authors: Roswandi Iwan , Junaedi Didi , Riadi Selamet , Rokhim Muh
Published: March 2022

Sistem dan kondisi kerja yang baik berdampak pada produktivitas dari karyawan. Salah satu faktor pendukung perindustrian Jepang adalah adanya program yang selalu ditaati Bersama dan inovasi secara terus menerus. Tetapi, hal tersebut dapat dilakukan karena langkah pertama yang selalu dikedepankan yaitu proses kerja 5S. Penempatan bahan baku material kurang rapi menyebabkan proses handling memerlukan waktu yang lama. Penelitian ini bertujuan mengetahui penyebab setup yang lama diareal injection dan melakukan perbaikan sehingga meningkatkan jumlah produksi. Penyebab terjadinya delay waktu pada mesin injection adalah penempatan bahan baku material kurang rapi sehingga saat proses handling memerlukan waktu yang lama, perbaikan dengan melakukan training 5S untuk penempatan material bahan baku. Screw injection problem saat setup, perbaikan dengan Preventive Maintenance dan Autonomous Maintenance secara berkala. Pergantian spare part SOP tidak berjalan dengan baik, perlu Retraining kepada seluruh operator. Bahan baku kotor sehingga output hasil produksi NG, dilakukan pemilahan saat penempatan bahan baku, dan Retrainning Operator.
Turismo e interações espaciais no destino Natal/RN
Authors: Costa Hugo Aureliano da , Fonseca Maria Aparecida Pontes da
Published: March 2022

O presente artigo objetiva analisar as interações espaciais verificadas em Natal decorrentes da expansão e promoção da atividade turística, evidenciando a natureza seletiva da territorialização desta atividade. Nos procedimentos metodológicos, recorreu-se à pesquisa documental, bibliográfica e trabalho de campo. Analisaram-se as conexões espaciais do destino Natal/RN a partir da atividade turística, tendo como base dados dos Meios de Hospedagens, turistas e dos trabalhadores dos meios de hospedagens, com o intuito de discutir as interações espaciais e relações interescalares entre a capital potiguar, o Brasil e o mundo. Constatou-se a existência de múltiplas territorializações decorrentes do funcionamento da atividade turística e que os diferentes agentes do turismo atuam de forma espacialmente seletiva, sendo as redes geográficas condição sine qua non para a realização da atividade. Por fim, concluiu que a cidade de Natal é um importante nó da rede turística potiguar, assumindo forte centralidade em função dos fluxos originados pela atividade turística, conectando-a a espaços multiescalares.
O discurso de educação patrimonial como subsídio aos usos do espaço patrimonializado do centro histórico de Belém: construção discursiva do fórum circular
Authors: Barros Magaly Caldas , Tavares Maria Goretti da Costa
Published: March 2022

Este artigo objetiva analisar de que maneira o discurso de educação patrimonial substancia os usos do espaço patrimonializado do Centro Histórico de Belém (CHB). Trataremos da construção do Fórum Circular a partir da perspectiva teórica de participação popular. Buscamos também explorar como são discutidos no Fórum Circular os usos do espaço efetivados pelas ações desenvolvidas durante o Projeto Circular Campina-Cidade Velha (PC). Por fim, pretendemos identificar as práticas relacionadas à educação patrimonial desenvolvida pelo Projeto e tecer uma análise discursiva destas. Nossa ideia é defender a hipótese de que o PC desenvolve diversas práticas relacionadas ao uso dos espaços patrimonializados. Um dos discursos que sustentam tais práticas relaciona-se à educação patrimonial, por esta caracterizar um diálogo entre comunidades e agentes responsáveis por ações educativas. Assim, o discurso de educação patrimonial substancia os usos do patrimônio no espaço do CHB na efetivação do PC. Problematizamos a conexão do discurso de educação patrimonial produzido pelo PC com a espacialização das práticas realizadas pelos parceiros, evidenciando as forças na disputa pela tomada de decisão sobre o espaço patrimonializado. Somada a outras pesquisas sobre o tema, observamos a importância da educação patrimonial no contexto da participação popular. As implicações concentram-se nos direitos sociais, uma vez a educação patrimonial enquanto instrumento de valorização do patrimônio histórica das cidades, e no âmbito das políticas públicas, visto que a educação patrimonial pode ser vista como mecanismo de partida à formulação de políticas públicas de preservação do patrimônio ao passo que compõe estratégias de ativação social (BARROS, 2018).
A teoria do espaço turístico: conceitos, valores hierárquicos e suas redes turísticas no nordeste do Rio Grande do Sul
Authors: César Pedro
Published: March 2022

Nesta pesquisa, faz-se uma aproximação dos valores abstratos da Teoria do Espaço Turístico com suas representações concretas. Sabe-se que o Turismo, como campo científico e prático, tem muito de seu estatuto definido no seu reconhecimento como atividade eminentemente territorial. Essa teoria dá subsídios para formular hierarquias localizacionais. Espera-se, inicialmente, ao aportar o seu ambiente e a atividade, reforçar seu papel na formulação de redes geográficas e turísticas. Ao estabelecer seu recorte espacial na Serra Gaúcha – RS, faz-se levantamentos indiretos junto aos órgãos dos governos federal e municipais e a pesquisas jornalísticas e de ambientes informacionais. Confrontam-se esses com observação direta realizada em visitas aos municípios e especificamente em áreas de apropriações turísticas. Com esse arcabouço teórico e prático, qualificam-se as formações hierárquicas para compreender o seu papel localizacional definidas pela Teoria. Conclui-se acerca de sua aplicação que os indicadores atribuídos na sua origem teórica devem agregar novos fatores como as funções sociais do espaço, reconhecendo as sociedades presentes, além de fatores físicos que interferem na composição dos destinos turísticos.
Geografia dos sabores: uma abordagem para o enoturismo
Authors: Torres Thaís Gomes , Costa Benhur Pinós da
Published: March 2022

A Geografia do sabor recebeu contribuição da tradição da geografia cultural e humanista com embasamento nos estudos da natureza e na experiência geográfica para o aprofundamento de diálogos interdisciplinares. A geografia do sabor permite analisar a alimentação através da experiência espacial humana com os sabores. Sabores que criam lugares e retratam o envolvimento das pessoas na experiência do prazer além do observar. Para assimilar a relação entre sabores e lugares na prática do enoturismo devemos levar em conta a compreeensão da experiência humana. Nesta perspectiva o presente trabalho busca abordar uma reflexão apoiada no paradigma da fenomenologia para discorrer sobre a relação da geografia do sabor e o enoturismo.
SARS-CoV-2, HIV, and TB Triple Co-infection
Authors: Kuate Marius Paulin Ngouanom , Bongomin Felix , Ndip Roland
Published: March 2022

COVID-19, TB and HIV are infectious diseases of global public health
concern. Triple Co-infection with these diseases can create a diagnostic
and therapeutic dilemma. We present a case of a young Cameroonian woman
with SARS-CoV-2 – HIV-TB triple co-infection. Early diagnosis and
appropriate management yielded an excellent outcome.
A High-Throughput Chaotic Advection Microreactor for Preparation of Uniform and Aggregated BaSO4 Nanoparticles
Authors: Yang Hua , Wei Shi-Xiao , Chen Han , Chen Lang , Au Chak-tong , Xie Ting-Liang , Yin Shuang-Feng
Published: March 2022

A high-throughput (105.5 g/h) passive four-stage asymmetric oscillating
feedback microreactor using chaotic mixing mechanism was developed to
prepare aggregated BaSO4 particles of high primary nanoparticle size
uniformity. Three-dimensional unsteady simulations showed that chaotic
mixing could be induced by three unique secondary flows (i.e., vortex,
recirculation, and oscillation), and the fluid oscillation mechanism was
examined in detail. Simulations and Villermaux-Dushman experiments
indicate that almost complete mixing down to molecular level can be
achieved and the prepared BaSO4 nanoparticles were with narrow primary
particle size distribution (PSD) having geometric standard deviation,
σg, less than 1.43 when the total volumetric flow rate Qtotal was larger
than 10 mL/min. By selecting Qtotal and reactant concentrations, average
primary particle size can be controlled from 23 to 109 nm as determined
by microscopy. An average size of 26 nm with narrow primary PSD (σg =
1.22) could be achieved at Qtotal of 160 mL/min.
GLOBAL CRISES AND CYBERSECURITY ATACKS – AN ANALYSIS DURING THE COVID-19 PANDEMIC
Authors: Mertoiu George B. , Mesnita Gabriela
Published: March 2022

The COVID-19 pandemic has affected all nations in various ways, both economically and especially socially. The new normality, as social behavior dictated by the restrictions imposed, sustained online interaction, a factor that allowed an increase in cyberattacks. This paper intends to analyze the cyberattacks conducted during the COVID-19 pandemic, starting from a series of international events such as the crisis in Venezuela or Ukraine. A part of this study is a quantitative analysis of the results obtained from consulting the Scopus database. In this part, in addition to the most important authors and key words used, we aimed to find if the countries that are the main targets of cyberattacks are also involved in researching cybersecurity during pandemic. Cyberattacks are analyzed in terms of motivation and targets, aiming to identify possible solutions based on the modus operandi of attackers and what will be the next steps in the research.
COHERENCE OF THE SPENDING OF EU FUNDS IN THE SZCZEBRZESZYN MUNICIPALITY IN POLAND IN 2014–2020: EXPECTATIONS OF INHABITANTS FOR LOCAL DEVELOPMENT AND IMPROVING THE QUALITY OF LIFE
Authors: Pomianek Iwona , Hasiec Agnieszka
Published: March 2022

Local development, understood as a process of significant changes, is conditioned by both endogenous and exogenous resources, including EU subsidies. The main objective of the study is to identify the areas in which EU projects were implemented by the Szczebrzeszyn commune in Poland in 2014–2020. In addition, the study analyzes the opinions of the commune inhabitants on the legitimacy of investments implemented with EU funds, in the context of the socio-economic development of the commune and improvement of the quality of life. A CAWI survey was conducted among the inhabitants of the municipality, and the changes that have occurred due to the EU funding were analyzed. Most respondents noticed the development within the Szczebrzeszyn municipality in the last ten years. The use of EU funds allowed to increase the length of the sewage network and bicycle path, as well as to install solar collectors and photovoltaic panels. The respondents claimed that some of the projects positively impacted their quality of life.
Accounting Quality and Household Stock Market Participation
Authors: Huang Shawn X. , Kim Min
Published: March 2022

SYNOPSIS

Recent research documents that there is significant variation in stock market participation by state and suggests that there may be state-specific factors that determine stock market participation of U.S. households. Using household survey data, we examine how state-level, public-company accounting quality affects households’ stock market participation decisions. We find that households residing in states where local public companies have better accounting quality are more likely to invest in stocks. Also, those households invest greater amounts of their wealth in the stock market. Furthermore, we present some evidence that accounting quality affects stock market participation through local press coverage. Additional cross-sectional tests show that the effect of accounting quality on stock market participation is more pronounced among less affluent and less educated households, consistent with prior findings that familiarity with and trust in the stock market are more important for those types of households to make stock investments.

JEL Classifications: D14; G11; M41.
The Creation of One Truth: Single-Ledger Entries for Multiple Stakeholders Using Blockchain Technology to Address the Reconciliation Problem
Authors: Gomaa Ahmed A. , Gomaa Mohamed I. , Boumediene Salem L. , Farag Magdy S.
Published: March 2022

Reconciliation of transactions between multiple parties is a time-consuming process. This paper presents a new conceptual framework that may lower costs and shorten the reconciliation time. The proposed framework recommends recording transactions on the blockchain before populating the transacting parties’ respective enterprise resource planning (ERP) systems, which will be the source of a single truth. This information flow will result in all involved parties having access to the same transaction details. Further, the paper presents a technical feasibility demonstration with two examples, where all involved parties are executing transaction details on the blockchain after meeting the governing smart contract constraints using their digital wallets. The new conceptual framework has been specifically designed to create one truth for all parties involved in a transaction that in turn may eliminate what is perceived to be unnecessary redundancy in current accounting systems.
Incidence and Characteristics of Remission of Type 2 Diabetes in England: A Cohort Study Using the National Diabetes Audit
Authors: Holman Naomi , Wild Sarah H , Khunti Kamlesh , Knighton Peter , O’Keefe Jackie , Bakhai Chirag , Young Bob , Sattar Naveed , Valabhji Jonathan , Gregg Edward W
Published: March 2022

Objective: To assess the incidence of remission of type 2 diabetes in routine
care settings.

Research design and methods: People with type 2 diabetes (HbA1c ≥48 mmol/mol (6·5%) or <48
mmol/mol (6·5%) with a prescription for glucose lowering medications) alive on
1st April 2018 were identified from a national collation of health
records in England and followed until 31st December 2019. Remission
was defined as two HbA1c measurements <48 mmol/mol at least 182 days apart,
with no prescription for glucose lowering medications 90 days prior to these
measurements.

Results: In 2,297,700 people with type 2 diabetes the overall incidence of
remission per 1000 person-years was 9·7 (95% CI 9·6-9·8), and 44·9 (95% CI 44·0-45·7)
in 75,610 (3.3%) people who were diagnosed less than a year. In addition to shorter duration of diagnosis,
baseline factors associated with higher odds of remission were no prescription
for glucose lowering medication, lower HbA1c and BMI, BMI reduction, White
ethnicity, female sex and lower socio-economic deprivation. Among 8940
(0.4%) with characteristics associated with remission (diagnosed less than two
years, HbA1c <53 mmol/mol, prescribed metformin alone or no glucose lowering
medications, BMI reduction of ≥10%) incidence of remission was 83·2 (95% CI 78·7-87·9) per 1000 person-years.

Conclusions: Remission of type 2 diabetes was generally infrequent in routine
care settings but may be a reasonable goal for a subset of people who loose significant
weight shortly after diagnosis. Policies that encourage intentional remission
of type 2 diabetes should seek to reduce the ethnic and socioeconomic inequalities
identified.
Association of Type 2 Diabetes Risk Perception With Interest in Diabetes Prevention Strategies Among Women With a History of Gestational Diabetes
Authors: Vu Amanda , Turk Norman , Duru Kenrik , Mangione Carol M. , Panchal Hemali , Amaya Sarah , Castellon-Lopez Yelba , Norris Keith , Moin Tannaz
Published: March 2022

Objectives. The aims of this study were to identify
predictors of perception of type 2 diabetes risk in women with a history of gestational
diabetes mellitus (GDM) and to determine factors associated with interest in
evidence-based strategies for type 2 diabetes prevention.

Research Design and Methods. We surveyed women with a history of
GDM who had not progressed to type 2 diabetes from a large academic medical
center. We used multivariate logistic regression to assess predictors of high levels
of perception of type 2 diabetes risk. We also tested associations between risk
perception and interest in a lifestyle change program and/or metformin therapy.

Results. In our diverse sample of
264 women, 28% were unaware that GDM is a risk factor for incident type 2
diabetes after pregnancy, and 48% believed their personal risk of type 2
diabetes was low. In multivariate analyses, family history of diabetes (odds
ratio [OR] 2.2, 95% CI 1.2–4.4) and knowledge of GDM as a risk factor for
incident type 2 diabetes (OR 4.5, 95% CI 2.1–9.8) were significant predictors of
greater perception of type 2 diabetes risk. Women with higher risk perception were
more likely to express interest in a lifestyle change program compared to women
with lower risk perception (OR 2.4, 95% CI 1.3–4.5).

Conclusion. Although some women are aware that GDM
is a risk factor for incident type 2 diabetes, many still perceive their own
risk of developing type 2 diabetes as low. Higher risk perception predicted
interest in an evidence-based diabetes prevention program, highlighting the
importance of personalized risk assessment and communication about risk for women
who have had GDM.
Diabetes Remission in the Alliance of Randomized Trials of Medicine Versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D)
Authors: Kirwan John P. , Courcoulas Anita P. , Cummings David E. , Goldfine Allison B. , Kashyap Sangeeta R. , Simonson Donald C. , Arterburn David E. , Gourash William F. , Vernon Ashley H. , Jakicic John M. , Patti Mary Elizabeth , Wolski Kathy , Schauer Philip R.
Published: March 2022

OBJECTIVE: The overall aim of the
Alliance of Randomized Trials of Medicine versus Metabolic Surgery in Type 2
Diabetes (ARMMS-T2D) consortium is to assess the durability and longer-term
effectiveness of metabolic surgery compared to medical/lifestyle management in
patients with type 2 diabetes (NCT02328599).

RESEARCH
DESIGN AND METHODS: 316 patients with type 2 diabetes previously
randomized to surgery (N=195) or medical/lifestyle therapy (N=121) in the STAMPEDE,
TRIABETES, SLIMM-T2D and CROSSROADS trials were enrolled into this prospective
observational cohort. The primary outcome was the rate
of diabetes remission (hemoglobin A1c (HbA1c) ≤6.5% for 3 months without
usual glucose-lowering therapy) at three years. Secondary outcomes included glycemic
control, body weight, biomarkers, and comorbidity reduction.

RESULTS: Three-year
data were available for 256 patients with mean age 50±8.3 years,
BMI 36.5±3.6 kg/m2 and duration of diabetes 8.8±5.7 years. Diabetes remission was achieved in more participants
following surgery than medical/lifestyle intervention (60/160 (37.5%) vs. 2/76
(2.6%), respectively, p<0.001). Reductions in HbA1c (Δ = -1.9±2.0
vs. -0.1±2.0%, p<0.001), fasting plasma glucose (Δ = -52[-105, -5] vs. -12[-48,
26] mg/dL, p<0.001) and BMI (Δ = -8.0±3.6 vs. -1.8±2.9 kg/m2, p<0.001)
were also greater after surgery. The percentage of patients using medications to control diabetes,
hypertension, and dyslipidemia were all lower after surgery (p<0.001).

CONCLUSIONS: Three-year follow-up of
the largest cohort of randomized patients followed to date demonstrates that metabolic/bariatric
surgery is more effective and durable than medical/lifestyle intervention in remission
of type 2 diabetes, including among individuals with class 1 obesity, for whom
surgery is not widely used.
Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
Authors: Nielsen Casper K. , Øhrstrøm Caroline C. , Kielgast Urd L. , Hansen Dorte L. , Hartmann Bolette , Holst Jens J. , Lund Asger B. , Vilsbøll Tina , Knop Filip K.
Published: March 2022

OBJECTIVE To
investigate the efficacy and safety of dasiglucagon, a novel stable glucagon analog
in a liquid formulation, in Roux-en-Y gastric bypass (RYGB)-operated individuals
suffering from post-bariatric hypoglycemia (PBH).

RESEARCH
DESIGN AND METHODS In a randomized, double-blind,
placebo-controlled crossover trial, 10 RYGB-operated participants with continuous
glucose monitoring (CGM)-verified PBH were randomized to three trial days, each
consisting of a 240-minute standardized liquid mixed meal test (MMT) with the subcutaneous
injection of either placebo, 80 µg, or 200 µg dasiglucagon.

RESULTS Compared
with placebo, treatment with both 80 and 200 µg dasiglucagon raised nadir plasma
glucose (PG) (placebo: 3.0 ± 0.2 mmol/L (mean ± standard error of the mean (SEM));
80 µg dasiglucagon: 3.9 ± 0.3 mmol/L, P = 0.002; 200 µg dasiglucagon:
4.5 ± 0.2 mmol/L, P = 0.0002) and reduced time in hypoglycemia (PG < 3.9 mmol/L) by 70.0 minutes (P = 0.030 and P = 0.008).

CONCLUSION Single-dose administration of dasiglucagon effectively
mitigated postprandial hypoglycemia.
Fenofibrate and Heart Failure Outcomes in Patients With Type 2 Diabetes: Analysis From ACCORD
Authors: Ferreira João Pedro , Vasques-Nóvoa Francisco , Ferrão Diana , Saraiva Francisca , Falcão-Pires Inês , Neves João Sérgio , Sharma Abhinav , Rossignol Patrick , Zannad Faiez , Leite-Moreira Adelino
Published: March 2022

Objectives:
Patients with type 2 diabetes (T2D) have a high risk for developing heart
failure (HF), which is associated with poor prognosis. Fenofibrate may reduce
HF events through multiple mechanisms. To study the effect of fenofibrate (vs.
placebo) in HF outcomes among patients with T2D receiving simvastatin enrolled
in the ACCORD-Lipid trial.

Research
design and Methods: Cox regression analysis with
background glucose-lowering strategy as stratification variable. The median
follow-up was 4.7 years.

Results:
A total of 5518 patients were included. The median age was 62 years and 31%
were women. A prior HF history was present in 5% of the patients. The composite
outcome of HF hospitalization or cardiovascular death occurred in 190 (6.9%)
patients in the fenofibrate group vs. 228 (8.3%) in the placebo group: HR 0.82,
95%CI 0.68-1.00, P =0.048. The beneficial effect of fenofibrate to reduce HF
hospitalizations or cardiovascular death was present among patients receiving
standard glucose-lowering strategy: HR 0.64, 95%CI 0.48-0.85, and not among
patients receiving intensive glucose-lowering strategy: HR 1.02, 95%CI
0.79-1.33, interaction P =0.017. A similar pattern was observed
for HF hospitalizations alone. The effect of fenofibrate on blood lipids was
not influenced by background glucose-lowering therapy in a clinically important
manner. Fenofibrate caused more transient worsening eGFR
events but slowed the long-term eGFR decline.

Conclusion:
In patients with T2D treated with simvastatin, fenofibrate reduced the composite
of HF hospitalizations or cardiovascular mortality, an effect that was seen
predominantly in patients with standard background glucose-lowering therapy.
Efektivitas Penggunaan Sistem Computer Based Test dan Paper Based Test dalam Pelaksanaan Ujian Tengah Semester Bahasa Indonesia di SMPN 6 Singaraja
Authors: Wardani Selfy Udayana Kusuma
Published: March 2022

Penelitian ini bertujuan mendeskripsikan proses penggunaan sistem berbasis komputer atau Computer Based Test (CBT) dan sistem berbasis kertas atau Paper Based Test (PBT),  kesiapan siswa dalam mengikuti UTS CBT dan PBT, keefektivan penggunaan CBT dan PBT dalam pelaksanaan UTS di SMPN 6 Singaraja. Subjek pada kajian studi ini ialah Panitia Pelaksana UTS, guru dan siswa. Objek penelitian ini adalah penggunaan CBT dan PBT dalam pelaksanaan UTS. Penelitian ini berjenis deskriptif dengan menggunakan pendekatan kualitatif. Data dikumpulkan dalam metode observasi, wawancara, kuisioner dan dokumentasi.  Tahap analisis data meliputi reduksi data, penyajian data dan pengambilan simpulan. Hasil penelitian ini menunjukkan bahwa proses penggunaan sistem berbasis komputer dan kertas dalam pelaksanaan UTS Bahasa Indonesia di SMPN 6 Singaraja sudah berjalan dengan baik melalui tahap perencanaan dan tahap pelaksanaan. Kesiapan siswa dalam mengikuti UTS sudah tercapai dengan baik (94,62%) siswa memberikan respons yang positif, siswa sudah memiliki kesiapan dalam mengikuti UTS CBT dan PBT di SMP Negeri 6 Singaraja. Kesiapan siswa dapat dilihat dari beberapa aspek yaitu kondisi fisik, mental, emosional, dan pengetahuan. Penggunaan CBT dan PBT tergolong efektif karena sudah memenuhi beberapa aspek yaitu validitas, reabilitas, objektif, praktis dan ekonomis.Kata Kunci:  Computer Based Test; Paper Based Test; Efektivitas.
Pengembangan Video Pembelajaran Berbasis Model CORE pada Pembelajaran Bahasa Indonesia Terintegrasi Tema 1 Kelas V SD
Authors: Priantini Dewa Ayu Made Manu Okta
Published: March 2022

Permasalahan yang melatarbelakangi penelitian ini adalah kurangnya media pembelajaran bagi siswa pada pembelajaran bahasa Indonesia sehingga minat siswa untuk belajar kurang maksimal. Penelitian ini merupakan penelitian pengembangan (research and devlopment) model ADDIE. Subyek uji coba penelitian adalah siswa kelas V SD N 6 Kesiman. Instrumen pengumpulan data yang digunakan berupa lembar evaluasi (angket). Analisis data menggunakan analisis deskriptif kualitatif dan deskriptif kuantitatif. Hasil penilaian terhadap produk media dilaksanakan berdasarkan enam aspek, yaitu: aspek isi bidang studi/ dengan persentase tingkat pencapaian 88.05% (layak); ditinjau dari aspek desain pembelajaran dengan persentase tingkat pencapaian 84.65% (layak); ditinjau dari aspek media pembelajaran dengan persentase tingkat pencapaian 87.00% (layak); ditinjau dari aspek uji coba perorangan, dengan persentase tingkat pencapaian 91.55% (sangat layak); uji coba kelompok kecil, dengan persentase tingkat pencapaian 93.40% (sangat layak); dan ditinjau dari aspek uji coba lapangan dengan persentase tingkat pencapaian 92.46% (sangat layak). Dengan demikian produk media video pembelajaran ini memiliki tingkat validitas yang baik dan layak untuk digunakan dalam proses pembelajaran bahasa Indonesia.
Pengaruh Novel Katarsis Karya Anastasia Aemilia Terhadap Psikologis Pembaca
Authors: Lestari Nabila Setio , Wibowo Wahyu , Waslam Waslam
Published: March 2022

Karya sastra mempunyai arti sebuah hasil dari pemikiran atau ide yang dituangkan oleh seseorang melalui tahapan pembuatan karya. Novel merupakan bentuk hasil karya yang termasuk ke dalam prosa fiksi. Tujuan penelitian ini ialah (1) mengetahui pengaruh novel Katarsis terhadap psikologis pembaca usia 20 sampai 31 tahun, (2) mengetahui cara novel Katarsis memengaruhi psikologis pembaca, (3) mengetahui dampak yang ditimbulkan setelah membaca novel Katarsis. Penelitian ini menggunakan metode deskriptif kualitatif. Sampel yang digunakan sebanyak 20 orang pembaca novel Katarsis berusia 20 sampai 31 tahun. Pengaruh novel Katarsis terhadap psikologis pembaca adalah cemas berlebihan. Mayoritas pembaca memilih tingkah laku tokoh sebagai cara novel Katarsis memengaruhi psikologis pembaca. Sebanyak 80% pembaca memilih tidak ada dampak yang ditimbulkan setelah membaca novel Katarsis. Sebanyak 5% pembaca memilih dampak yang ditimbulkan ialah rasa ingin melukai diri sendiri (self injury), dan  sebanyak 5% pembaca memilih dampak yang ditimbulkan ialah ingatan atau perasaan untuk membalas dendam.
Analisis Produksi dan Perilaku Konsumtif dalam Karya Sastra Bergenre Chicklit dan Teenlit
Authors: Sekarningrum Hilary Relita , Dewi Novita
Published: March 2022

Perilaku konsumtif yang saat ini sesuai dengan kondisi masyarakat Indonesia membuat hilangnya karakter Bangsa Indonesia. Perilaku konsumtif tercermin dalam isi cerita dalam sebuah karya sastra yakni Cewek Matre karya Alberthine Indah, Cintapuccino karya Ica Rahmanti, Rahasia Bintang karya Dyan Nuranindya dan  Suatu Sore karya Nurul Arifin.Tujuan dari penelitian ini adalah untuk menganalisis produksi konsumtif dalam karya sastra bergenre chicklit dan teenlit. Metode yang digunakan dalam penelitian ini yakni studi literatur dengan mencari referensi teori yang relevan dengan kasus atau permasalahan yang ditemukan. Hasil penelitian menunjukkan perilaku konsumtif terdapat dalam novel yang dikaji. Novel Cewek Matre menceritakan gaya hidup yang mewah dengan membeli barang-barang yang mahal. Dalam novel Cintapucciono diceritakan bahwa gaya hidup mewah dengan makan di berbagai restoran ternama. Pada novel Rahasia Bintang perilaku konsumtif tercermin dari tokoh-tokoh yang kongkow di restoran ternama sedangkan pada novel Suatu Sore, perilaku konsumtif nampak pada tokoh-tokoh yang hobi belanja. Perilaku konsumtif juga mempengaruhi produksi suatu barang, dalam hal ini adalah karya sastra.
Analisis Variasi Konsultatif pada Gilir Bicara dalam Pembelajaran Daring Bahasa Indonesia di SMK PGRI 1 Giri Banyuwangi
Authors: Ambarsari Tri Agung Bayu , Mujianto Gigit
Published: March 2022

Penelitian ini bertujuan mendeskripsikan variasi bahasa konsultatif, bentuk model fungsional gilir bicara, dan proses gilir bicara antara guru dan siswa. Penelitian kualitatif ini menggunakan pendekatan sosiolinguistik. Metode yang digunakan adalah deskriptif analisis. Sumber data adalah video pembelajaran bahasa Indonesia di SMK PGRI 1 Giri Banyuwangi (https://youtu.be/xnK7rWhzie8). Bentuk data penelitian ini berupa kutipan kata, frasa, klausa atau kalimat yang terdapat dalam video pembelajaran. Hasil penelitian ini menunjukkan penggunakan variasi bahasa konsultatif berupa kalimat interogatif, kalimat sapaan, kalimat meminta, memberi saran dan pendapat, kalimat penjelas, serta kalimat ekslamatif. Bentuk model fungsional gilir bicara guru dan siswa yaitu gilir bicara, jeda, overlaps, backchannel, dan pasangan ajesensi. Pada proses gilir bicara guru dan siswa terjadi overlaps atau tumpang tindih tuturan. Overlaps merupakan model fungsional yang sering muncul.
Dinámica del capital humano en la industria aeroespacial en México
Authors: Castillo Rodriguez Jesús
Published: March 2022

La industria aeroespacial es una industria manufacturera que se centra en el diseño, fabricación de fuselajes, concepción y producción de motores de aviación, así como sistemas eléctricos y mecánicos. Dado su impacto en otras aéreas de la economía, es conocida como una industria de industrias. En México, el desempeño de la industria aeroespacial en los años recientes ha mostrado un particular crecimiento derivado de la especialización de la mano de obra. Este artículo tiene como objetivo determinar y analizar la injerencia que tiene el capital humano en la producción de equipo aeroespacial en México. Se parte de la hipótesis de que el capital humano imprime a esta industria fuertes ventajas competitivas para localizarse en el país. La metodología empleada consiste en replicar un modelo empírico econométrico de regresión logarítmica. Los resultados previos indican un ambiente productivo favorable para dicha industria, caracterizado por un estricto control de calidad del sector laboral.
Clinical Efficacy of Patient-specific Implants Manufactured using Direct Metal Laser Sintering (DMLS) Technology in Patients with Mandibular Defects
Authors: Chernohorskyi Denis , Voller Marharyta , Vasilyev Aleksandr , Chepurnyi Yurii , Kopchak Andrii
Published: March 2022

Purpose: The purpose of this study was to compare the clinical efficacy of patient-specific implants (PSIs) in patients with mandibular defects in the early and distant postoperative period.
Materials and Methods: The surgical results in 60 patients with postoperative and posttraumatic mandibular discontinuous defects were analyzed. The patients were treated at the Center of Maxillofacial Surgery and Dentistry, Kyiv Regional Clinical Hospital in the period from 2015 to 2020.
Results: Despite certain functional limitations and residual aesthetic deficiency, 34 patients (85%) of the main group and 9 (45 percent) of the control group noted an improvement in their quality of life and were satisfied with the results of the operation (р < 0.05).
Conclusions: The use of PSIs, compared to traditional methods of bone grafting, allow to achieve a more accurate restoration of the anatomical shape of the mandible in areas with complex geometry and probably better aesthetic results, and significantly reduces the frequency of secondary displacement of bone fragments due to plastic deformation and destruction of fixation elements (p < 0.05). At the same time, it probably does not affect the frequency of purulent-inflammatory complications, unsatisfactory clinical results and the effectiveness of the restoration of masticatory function in patients with mandibular defects.
Does Corporate Governance Affect Dividends? Case Study in Indonesia Stock Exchange and Malaysia Stock Exchange
Authors: Hermawan Budy Wijaya , Murhadi Werner Ria , Ernawati Endang
Published: March 2022

Abstract – This study aims to analyze the effect of good corporate governance such as the number of commissioners, the number of commissioner meetings, the number of female commissioners, the independent commissioners on the dividend payout ratio in manufacturing companies listed on the Indonesia Stock Exchange and the Malaysia Stock Exchange. Malaysia was chosen because has a dividend payout rate close to Indonesia. This research uses a quantitative approach using multiple linear regression methods. The research used objects of 435 observations on the Indonesia Stock Exchange and 530 observations on the Malaysia Stock Exchange. The independent variables used are independent commissioners, board of commissioners meetings, size of commissioners, female commissioners. The results of the study using observations on the Indonesia Stock Exchange found that independent commissioners have a significant positive effect while the rest have an insignificant effect on the dividend payout ratio. Meanwhile, the results of the study using observations on the Bursa Malaysia found that the size of the commissioners and board of commissioners' meetings had a significant negative effect on the dividend payout ratio. Meanwhile, independent commissioners and female commissioners have a significant positive effect on the dividend payout ratio.
Factors affecting the Behavior Intention to Make Purchases Online On E-Commerce
Authors: Angelina Shania , Anandya Dudi , Indarini Indarini
Published: March 2022

This study aims to determine and analyze the factors that influence behavioral intentions to make purchases online with the object of research e-commerce. The focus of this research are performance expectancy, effort expectancy, social influence, anxiety, personal innovativeness, and behavioral intention to purchase online. Sources of data obtained by distributing online questionnaires. Data were collected through questionnaires distributed to 398 respondents an then analyzed using path analysis and MGA (Multigroup Analysis) with SPSS (Statistical Package for Social Sciences) and SmartPLS 3.0 software. The results showed that performance expectancy, effort expectancy, social influence, and personal innovativeness had a positive and significant influence on behavioral intention to purchase online for the entire group, but there was no difference in the effect between the two gender groups. On the other hand, anxiety has a negative and significant influence on behavioral intention to purchase online in both gender groups and has a significant difference in influence which is dominated by the female group compared to the male group.
The Effect of Perceived Service Quality, Perceived Value, Destination Image, Attitude to Visiting Behavior, Tourist Satisfaction on Tourist Loyalty
Authors: Reza Islamy Muhammad , D. Trisnawati Juliani , Rahayu Siti
Published: March 2022

This study aims to determine the effect of perceived service quality, perceived value, destination image, attitude to visiting behavior, tourist satisfaction on tourist loyalty of Teluk Hijau beach in Banyuwangi, East Java tourists. Teluk Hijau beach is one of the tourist attractions in Banyuwangi, which is known as a hidden paradise. It has a green bay with a unique form of white sand that can spoil the tourists’ eyes and has more tourists than other beaches in Banyuwangi. This research is based on causal research, which was tested empirically using questionnaire data from 150 respondents. The research analysis used Structural Equation Modeling (SEM) with SPSS 18 and AMOS 22 software. The results show that perceived service quality and perceived value have a significant effect on destination image, and destination image, attitude to visiting behavior, and tourist satisfaction have a significant effect on tourist loyalty.
The Existence of Suluk During the Achmad Government in Rokan Hulu District (2006-2016)
Authors: Diniari Weni , Ahmal Ahmal , Fikri Asyrul
Published: March 2022

The purpose of this study is to determine: (1) To determine the condition of the existence of Suluk during the reign of Achmad in Rokan Hulu Regency, (2) To know the development of Suluk during the reign of Achmad in Rokan Hulu Regency, (3) To find out the impact of the existence of Suluk on people's lives during the reign of Achmad in Rokan Hulu Regency. This study uses a historical approach, data collection methods with field studies in the form of interviews and documentation as well as archive and library studies. This research was conducted in Rokan Hulu Regency. After the data is collected, the data examiner is carried out with source criticism, namely by testing the authenticity of the sources obtained by comparing one data with another, such as comparing the results of interviews with written evidence. Based on the results of this study, it can be concluded, namely, (1) The existence of Suluk during the Achmad period looks quite good with an increase in the number of Suluk congregations, (2) Suluk has developed quite rapidly, this is evidenced by the construction of quite a lot of Suluk Surau, (3) for the community. Suluk is very influential in everyday life in society.
Historical Paradigm In The Face of Religious Radicalism in The21st Century
Authors: Rahmatullah Wildan Nanda , Rumambo Pandin Moses Glorino
Published: March 2022

Writing this article aims to discuss the rise of religious radicalism, especially in the 21st century. Then this article is also intended to address the widespread radicalism, especially in Indonesia, according to the paradigm of history. The research method that the author uses is a qualitative method with content analysis through a literature review. The author takes sources from 2 books, 12 journal articles, and 2 news stories from BBC and CNN. In this article, we will discuss the history of radicalism, what the historical paradigm of religious radicalism, how the radicalism impact of religion on people's lives every day, and how prevention is based on the paradigm of history. In this article, the author uses a qualitative approach in the form of content analysis, literature review of 12 journals, 2 books, and 2 news sources from BBC Indonesia and CNN Indonesia. The results of this study are that the authors find that in the 21st century, society is amid unrest due to radicalism. The action is not only in Indonesia but also in several other countries, which is disturbing the peace between religious communities. From this research, the author recommends that this article can be used as a reference in discussing the handling of religious radicalism in social life. The limitation of this research is the lack of data that the author can get due to technical constraints such as limited internet access and social restrictions due to the COVID-19 pandemic.
Historical Meme As a Solution to Improve Generation Z Nationalism in Indonesia
Authors: Rozikin Febri Choiru
Published: March 2022

The development of the world of technology brings various influences on society. This progression includes communication between members. Generation Z as a generation that has grown up together with technological developments faces a formidable challenge. The threat of nationalism identity erosion becomes a problem that will lead to their sense of nationalism. The historical meme comes as entertaiment and history education for society. From that, a question arises. How can historical meme solve the fading sense of generation Z nationalism in the social media era? This reseach will answer it. History learning is needed to overcome the issue of the fading sense of nationalism. Historical knowledge can strengthen one’s devotion for the nation itself through the delivery of historical values. As a generation that is synonymous with technology, conventional solutions are not very effective in instilling historical values.
Analítica del aprendizaje interdisciplinar con modalidad d-learning en contexto de COVID-19
Authors: Salica Marcelo Augusto
Published: March 2022

El presente artículo muestra los resultados de una investigación cuantitativa y cualitativa aplicada a un grupo único experimental de estudiantes de cuarto año de la escuela secundaria (N=51). El estudio se justifica por el inédito contexto generado por la pandemia de Coronavirus ocasionando el distanciamiento socioeducativo y que exigió cambiar la educación presencial por la formación de emergencia y remota. El objetivo se basa en evaluar los resultados del aprendizaje de la ciencia escolar con enfoque interdisciplinar y modalidad d-learning. Para ello se utilizó técnicas de la analítica del aprendizaje y la evaluación de las actitudes con enfoque Ciencia-Tecnología-Sociedad. Los resultados obtenidos verifican que la modalidad d-learning implementada funciona como un entorno de interacción conversacional e instrumental. Dicho entorno favorece las actitudes Ciencia-Tecnología-Sociedad con fundamentos en la ciencia erudita dado que los participantes dialogan entre sí y con los recursos del aula virtual.