bluuebunny/crossref_metadata_2025 huggingface dataset:
Cost analysis of a virtual retina clinic versus fully face-to-face clinics
Authors: Juaristi Leire , Mar Javier , Guibelalde Ane , Irigoyen Cristina
Published: November 2023

PURPOSE
To compare the cost of a virtual retina clinic (VRC) with that of fully face-to-face (F2F) clinics in the follow-up of stable retinal diseases.
METHODS
A cost-minimization analysis (CMA) was conducted by measuring resource utilization of patients treated at Donostia University Hospital, for monitoring tests, performed in conventional F2F visits in 2019, and through the VRC in 2020. Our previous study on the VRC effectiveness demonstrated the equivalence of the results of the VRC and F2F approaches, as required for CMA, and a VRC sensitivity of 100% for detecting progression. The unit costs were obtained from the hospital´s accounting system. Furthermore, indirect costs related to labor productivity losses in patients and their companions were analyzed.
RESULTS
No significant differences were found between the total direct direct costs of the VRC and conventional clinics in the follow-up of 481 patients with stable retinal diseases. The differences detected were that VRC staff costs were significantly lower (54.5% vs. 76.8% for F2F clinics) while its equipment costs were higher (32.8% vs. 10%). Overall, including the costs of productivity losses, the VRC is significantly less expensive than in-person care as it more than halves indirect costs.
CONCLUSION
This first study analyzing the costs of a VRC versus fully F2F clinics found that it is not more expensive for the follow-up of stable retinal diseases. Additionally, taking into account indirect costs, the VRC is less expensive, and once the equipment has been acquired, its costs are lower than those of conventional clinics.
Identification of potential 3CLpro inhibitors-modulators for human norovirus infections: An advanced virtual screening approach
Authors: Bhowmick Shovonlal , Mistri Tapan Kumar , Okla Mohammad K. , Saleh Ibrahim A. , AbdElgawad Hamada , Saha Achintya , Patil Pritee Chunarkar
Published: November 2023

The present study aimed to screen small molecular compounds as the human noroviruses (HuNoV) inhibitors/modulators that could be potentially responsible for exhibiting some level of inhibitory activity against HuNoV 3CLPro. The structural similarity-based screening against ChEMBL database is performed against known chemical entities which are presently under pre-clinical trial. Molecules that remained after the similarity search were considered molecular docking using SCORCH and PLANTS. On detailed analyses and comparisons with control molecule, 3 hits (CHEMBL393820, CHEMBL2028556 and CHEMBL3747799) were found to be potential for HuNoV 3CLpro inhibition. The binding interaction analysis revealed several critical amino acids to hold the molecules tightly at the close proximity site of the catalytic residues. Further, three MD simulation study was performed in triplicate to understand the binding stability and potentiality of the proposed molecule towards HuNov 3CLpro. The binding free energy based on MM-GBSA has revealed their strong interaction affinity with 3CLpro.
Characterizing the Racial Discrepancy in Hypoxemia Detection in VV-ECMO: An ELSO Registry Analysis
Authors: Kalra Andrew , Wilcox Christopher , Holmes Sari D , Tonna Joseph E , Jeong In Seok , Rycus Peter , Anders Marc M , Zaaqoq Akram M , Lorusso Roberto , Brodie Daniel , Keller Steven P. , Kim Bo Soo , Whitman Glenn J R , Cho Sung-Min
Published: November 2023

Importance: Skin pigmentation influences peripheral oxygen saturation (SpO2) measured by pulse oximetry compared to the arterial saturation of oxygen (SaO2) measured via arterial blood gas analysis. However, data on SpO2-SaO2 discrepancy are limited in venovenous-extracorporeal membrane oxygenation (VV-ECMO) patients. Objective: To determine whether there is racial/ethnical discrepancy between SpO2 and SaO2 in patients receiving VV-ECMO. We hypothesized VV-ECMO cannulation, in addition to race/ethnicity, accentuates the SpO2-SaO2 discrepancy due to significant hemolysis. Design: Retrospective cohort study of the Extracorporeal Life Support Organization Registry from 1/2018-5/2023. Setting: International, multicenter registry study including over 500 ECMO centers. Participants: Adults (≥ 18 years) supported with VV-ECMO with concurrently measured SpO2 and SaO2 measurements. Exposure: Race/ethnicity and ECMO cannulation. Main outcomes and measures: Occult hypoxemia (SaO2 ≤ 88% with SpO2 ≥ 92%) was our primary outcome. Multivariable logistic regressions were performed to examine whether race/ethnicity was associated with occult hypoxemia in pre-ECMO and on-ECMO SpO2-SaO2 calculations. Covariates included age, sex, temporary mechanical circulatory support, pre-vasopressors, and pre-inotropes for pre-ECMO analysis, plus single-lumen versus double-lumen cannulation, hemolysis, hyperbilirubinemia, ECMO pump flow rate, and on-ECMO 24h lactate for on-ECMO analysis. Results: Of 13,171 VV-ECMO patients (median age = 48.6 years, 66% male), there were 7,772 (59%) White, 2,114 (16%) Hispanic, 1,777 (14%) Black, and 1,508 (11%) Asian patients. The frequency of on-ECMO occult hypoxemia was 2.0% (N = 233). Occult hypoxemia was more common in Black and Hispanic versus White patients (3.1% versus 1.7%, P < 0.001 and 2.5% versus 1.7%, P = 0.025, respectively). In multivariable logistic regression, Black patients were at higher risk of pre-ECMO occult hypoxemia versus White patients (adjusted odds ratio [aOR] = 1.55, 95% confidence interval [CI] = 1.18–2.02, P = 0.001). For on-ECMO occult hypoxemia, Black patients (aOR = 1.79, 95%CI = 1.16–2.75, P = 0.008) and Hispanic patients (aOR = 1.71, 95%CI = 1.15–2.55, P = 0.008) had higher risk versus White patients. Furthermore, higher pump flow rate (aOR = 1.29, 95%CI = 1.08–1.55, P = 0.005) and higher on-ECMO 24h lactate (aOR = 1.06, 95%CI = 1.03–1.10, P < 0.001) significantly increased the risk of on-ECMO occult hypoxemia. Conclusions and Relevance: Hispanic and Black VV-ECMO patients experienced occult hypoxemia more than White patients. SaO2 should be carefully monitored during ECMO support for Black and Hispanic patients especially for those with high pump flow and lactate values at risk for occult hypoxemia.
The role of the E/S ratio in the SEIR model: A case study of the Ebola outbreak in West Africa (2014–2016)
Authors: Kwak Minkyu , Sun Xiuxiu , Wi Yunju , Nah Kyeongah , Kim Yongkuk , Jin Hongsung
Published: November 2023

In the SEIR model, the role of the E/S ratio in the epidemic model is analyzed. It is shown that transmission rate curves corresponding to various incubation periods cross at a single point denoted by Cross Point (CP), where it satisfies \(\frac{\text{d}}{\text{d}\text{t}}\left(E/S\right)=0\). The time-dependent reproduction number (Rt) approximately reaches 1 at the time of CP. The E/S ratio plays a key role in determining which point between CP and Rt = 1 appears first. As CP can be obtained without knowledge of the incubation period, it can be a useful measure to identify the epidemic status wherein the time-dependent reproduction number is very close to one. As a case study, we estimate the time-dependent transmission rate and the reproduction number of the SEIR model for the 2014–2016 Ebola outbreak in Sierra Leone and Guinea by solving the inverse problem. We identify CP and Rt = 1 and investigate the E/S ratio for various cases of S(0).
Mathematics Subject Classification 92-10
Prevalence and Risk Factors of Relapse in Pulmonary Sarcoidosis: A Systematic Review and Meta-analysis
Authors: Hashim Zia , Tripathy Naresh Kumar , Nath Alok , Gupta Mansi , Khan Ajmal , Jha Ajit Kumar , Kumar Anup
Published: November 2023

Background and Aim:
Relapses in pulmonary sarcoidosis (PS) adversely affect the clinical management and prognosis of the disease, but there is a paucity of data on their incidence and risks. We aimed to systemically review and meta-analyze the available studies for evaluating the pooled weighted incidence and risk factors for relapse in the disease.
Methods:
We systematically searched electronic databases, including PubMed, Google Scholar, Scopus and Embase, and performed a manual search to collect eligible studies published until 31 October 2023. The prevalence and risk factors for relapse of PS were analyzed by a random effect model using proportions with 95% confidence intervals (CIs).
Results:
Of the 1402 records retrieved, 26 studies met the inclusion criteria. All these studies were from tertiary centers. Mean age of the relapse groups was 45.94 years (SD 10.87). The prevalence of relapse in sarcoidosis (843 relapses in 2698 sarcoidosis subjects) varied from 11–67%, with a pooled prevalence of 0.34 [95% CI, 0.28–0.40]. Relapses were more common in blacks than in white individuals [0.72 (0.65–0.79) vs [0.27 (0.20–0.34), p = 0.00]. There were no significant differences in subgroups based on age, sex, location, or type of study. Although not reaching statistically significance, the number of relapses were higher in the female as compared to males [Risk difference 0.05(95% CI: -0.01-0.11, p = 0.09)].
Conclusion:
Our study shows a pooled incidence of PS relapse of 34%, suggesting a regular follow-up of the patients for early detection of relapse and improved prognosis of the disease.
Landscape of racial and ethnic health disparities in the All of Us Research Program
Authors: Lam Vincent , Sharma Shivam , Jordan I. King , Mariño-Ramírez Leonardo
Published: November 2023

The All of Us Research Program (All of Us) is an initiative led by the United States National Institutes of Health (NIH) whose goal is to advance research on personalized medicine and health equity through the collection of genetic, environmental, demographic, and health data from volunteer participants who reside in the United States (US). The program’s emphasis on recruiting a diverse participant cohort makes All of Us an effective platform for investigating racial health disparities. However, to our knowledge, there have been no attempts to catalog the landscape of racial and ethnic health disparities that exist in the All of Us participant cohort. In this work, we analyzed participant electronic health record (EHR) data to identify the diseases and disease categories in the All of Us cohort for which racial and ethnic prevalence disparities can be observed. In conjunction with these analyses, we developed the US Health Disparities Browser as an interactive web application that enables users to visualize differences in race- and ethnic-group specific prevalence estimates for 1,755 different diseases: https://usdisparities.biosci.gatech.edu/. The web application features a catalog of all diseases represented in the browser, which can be sorted by overall prevalence as well as the variance in prevalence across racial and ethnic groups. The analyses outlined here provide details on the nature and extent of racial and ethnic health disparities in the All of Us participant cohort, and the accompanying browser can serve as a resource through which researchers can explore these disparities.
A STUDY TO ASSESS THE KNOWLEDGE REGARDING DIGITALIZATION IN HEALTH CARE AMONG STAFF NURSES IN SELECTED HOSPITALS OF GANDHINAGAR
Authors:   Principal, Apollo Institute of Nursing, Gandhinagar (A Unit of Apollo Hospitals)., Mohan Singh Hari , Patel Priya ,   Nursing tutor, Apollo Institute of Nursing, Gandhinagar (A Unit of Apollo Hospitals)., F Group- ,   Final year B.Sc. Nursing students, Apollo Institute of Nursing, Gandhinagar (A Unit of Apollo Hospitals).
Published: November 2023

A Descriptive study was conducted Study to assess the knowledge regarding digitalization in healthcare among staff nurses in selected hospital of gandhinagar The general system model was used as conceptual framework. A quantitative approach with descriptive study design was used to achieve the objectives of the study. The sample consisted of 120 from selected hospital of Gandhinagar. The Simple random sampling technique was used to collect the sample. In the descriptive study the mean of the study was 13.29 with standard deviation 3.57 at 0.05 level of significance.0.05 level of significance.
BINDER RATE AND GRANULOMETRY EFFECTON THE PHYSICALAND MECHANICALPROPERTIES OF MAHOGANYSAWDUST PARTICLEBOARDS MADE WITH PEARLS BONE GLUE
Authors:   Polyethnic School of Lome, University of Lome, Po Box 1515, Lome, Togo., Drovou Soviwadan ,   Laboratory of Structure and Mechanic of materials (LaS2M), Polyethnic School of Lome, University of Lome, BP 1515, Lome, Togo.,   LaboratoryofResearchon Agriculture ResourcesandEnvironmentalHealth (LARASE), Universite de Lome, BP 20131 Lome, Togo.,   Laboratory for the Study and Research on Wood Material, University of Lorraine, Epinal, France., Banakinao Sinko ,   Polyethnic School of Lome, University of Lome, Po Box 1515, Lome, Togo.,   Laboratory of Structure and Mechanic of materials (LaS2M), Polyethnic School of Lome, University of Lome, BP 1515, Lome, Togo., Afio Ayarema ,   Polyethnic School of Lome, University of Lome, Po Box 1515, Lome, Togo.,   Laboratory of Structure and Mechanic of materials (LaS2M), Polyethnic School of Lome, University of Lome, BP 1515, Lome, Togo., Assogba Kassegne Komlan ,   Polyethnic School of Lome, University of Lome, Po Box 1515, Lome, Togo.,   Laboratory of Structure and Mechanic of materials (LaS2M), Polyethnic School of Lome, University of Lome, BP 1515, Lome, Togo., Pizzi Tony ,   Laboratory for the Study and Research on Wood Material, University of Lorraine, Epinal, France.,   Department of Physics, King Abdulaziz University, Jeddah, Saudi Arabia., Sanda Komla ,   LaboratoryofResearchon Agriculture ResourcesandEnvironmentalHealth (LARASE), Universite de Lome, BP 20131 Lome, Togo.,   Universite de Kara, Kara, Togo.
Published: November 2023

This work armtovalorizethesawdustofmahogany wood and the pearlsbone glue for environmental purposes.First, sawdust was sifted with three sieves respectively 0.8 1.6 and 2.5mm diameter. So, we have four granulometries (g) g â‰¤ 0.8 (G1), 0.8 < g â‰¤ 1.6 (G2), 1.6 < g â‰¤ 2.5 (G3), 2.5 < g â‰¤ 5 (G4) and the raw sawdust. particleboards are manufactured from sawdust by varyingsuchthebinder rate (5 6.5 7 7.5 8 10 12.5 and 15) and the granulometry. Second,physical properties such asthe density, thickness swelling (TS) Water absorption (WA) were searched. The mechanical properties (Modulus of Elasticity (MOE), the Modulus of Rupture (MOR) in flexion, and Internal Bond (IB)) are determined according to the standard ANSI A208.1 â€“ 2016[1]. The threshold fixed by the standard fortheMOE andtheMORarewidelyreached.Themanufactured particleboards are classified in the categoriesofmeandensity and can only be used in dry conditions.
CLINICAL SUSPICION OF LEFT VENTRICULAR APICAL THROMBUS - WHAT TO DO?: A CASE REPORT
Authors:   Chief, Pediatric and Adult Cardiology, Prakash Heart Station, Nirala Nagar, Lucknow, UP, India., Mehrotra Akhil , Shaban Mohammed ,   Cardiac Technician, Prakash Heart Station, Nirala Nagar, Lucknow, UP, India., Kacker Shubham ,   Lead PMO, Tech Mahindra, New Delhi, India.
Published: November 2023

Thrombi represent the most frequently found intracardiac masses. Left ventricular thrombus (LVT) is an important complication in patients with ischemic heart diseases and in those with dilated cardiomyopathy and systolic heart failure. The diagnosis of left ventricular thrombus remains important since anticoagulation will reduce the risk of systemic embolization and stroke. Despite advances in other imaging modalities, echocardiography remains the most important tool for diagnosis and risk stratification in patients predisposed to develop left ventricular thrombi. We are presenting a case report of 62 years old gentleman who had suffered from anterior wall myocardial infarction (AWMI) in the recent past, and now has developed LVT which was detected by contrast tuned imaging (CTI) based contrast echocardiography. This is a first case report of detection of LVT by this ingenious technology.
LA PRISE EN CHARGE DES ADENITES CERVICALES CHEZ LENFANT AUX URGENCES PEDIATRIQUES THE MANAGEMENT OF CERVICAL ADENITIS IN PEDIATRIC EMERGENCY CARE
Authors:   Service de Pediatrie du CHU Hassan II de Fes, Maroc., Taha Issam , Tadmouri Ilham ,   Service de Pediatrie du CHU Hassan II de Fes, Maroc., Hida Moustapha ,   Service de Pediatrie du CHU Hassan II de Fes, Maroc.
Published: November 2023

The objective of this study was to analyze the epidemiological, clinical and biological characteristics, as well as the management and evolution of children admitted and treated in pediatric emergencies for lymphadenitis. Over a period of two and a half years, we recorded 32 cases of lymphadenitis, 10 of which were cases of adenophlegmon. The average age of patients was 2 years and 5 months, and boys represented 66% of cases. In addition, 37% of children came from an unfavorable socio-economic background. The diagnosis of adenitis was established on the basis of swelling on the face and neck, accompanied by inflammatory signs. Biological analyzes revealed an infectious syndrome in the majority of patients. All children received antibiotic treatment, and surgical treatment was indicated in cases of adenophlegmon. The clinical outcome was favorable in the majority of cases.
COMPARATIVE ANALYSISOF SOFA VS. SAPS-II SCORE IN ASSESSING MORTALITY IN POLYTRAUMA PATIENTS FOR QUALITY MANAGEMENT
Authors:   General Surgery, Dr D Y Patil Medical College Navi Mumbai, Mumbai, IND., Budhkar Abhijit , Mahadik Abhishek ,   General Surgery, Dr D Y Patil Medical College Navi Mumbai, Mumbai, IND., Deolekar Sandesh ,   General Surgery, Dr D Y Patil Medical College Navi Mumbai, Mumbai, IND., Patil Aniket ,   General Surgery, Dr D Y Patil Medical College Navi Mumbai, Mumbai, IND., Jain Shshank ,   General Surgery, Dr D Y Patil Medical College Navi Mumbai, Mumbai, IND., Bajpai Sarang ,   General Surgery, Dr D Y Patil Medical College Navi Mumbai, Mumbai, IND., Beldar Nikhil ,   General Surgery, Dr D Y Patil Medical College Navi Mumbai, Mumbai, IND.
Published: November 2023

Background: The rise in severe combined traumas, underscores the need for accurate trauma assessment. The urgency to determine diagnoses and treatments for a variety of bodily injuries and disorders in polytrauma cases highlights the necessity for a robust classification system to evaluate trauma severity. Thus, the study aimed to assess the predictive value of the SOFA and SAPS II systems in evaluating mortality among polytrauma patients. Materials and Methodology: In this single centre prospective study, a total of 200 patients with injuries in at least two regions and an ISS > 16 were included. Demographic information and variables for SOFA and SAPS II calculations were recorded upon admission. SOFA scores were applied to evaluate organ failure, with variables assessed at different time points to provide comprehensive insights. SAPS II scores were derived using established procedures, considering vital signs, blood tests, and Glasgow Coma Scale (GCS) values. Mortality outcomes were monitored for up to 30 days post-admission. Result: The relationship between SOFA and SAPS II scores was significant, with a Chi-square value and p-value less than 0.001. Notably, elevated SOFA scores were linked to reduced survival rates, as affirmed by a substantial Chi-square association between SOFA scores and survival outcomes (Chi-square: 116.80, p < 0.001). The ROC Curve analysis with SOFAs AUROC at 0.924 and SAPS IIs AUROC at 0.99. SAPS II exhibited superior sensitivity and a lower false negative rate compared to SOFA. Conclusion: SOFA score effectively assesses organ dysfunction over time, while SAPS II excel in prognostic accuracy with an AUROC of 0.99, superior sensitivity, and reduced false negatives. SAPS II emerge as the more precise outcome predictor, aiding clinical decisions for enhanced patient care and improved outcomes in critical settings.
THE ETHICAL DILEMMA OF BIG TECH COMPANIES: A CASE STUDY OF MULTIPLE JOB HOLDINGS AND MOONLIGHTING IN INDIAN I.T. COMPANIES
Authors:   Associate Professor, Department of Management and Commerce, Maulana Azad National Urdu University (A Central University), Hyderabad, India., Sikandar M.A. , Honest Mohideen M.A. ,   Associate Professor, Motilal Nehru (Evening) College, University of Delhi., Nikhat Reshma ,   Assistant Professor, Department of Management and Commerce, Maulana Azad National Urdu University (A Central University), Hyderabad, India.
Published: November 2023

Post Covid-19 situation profoundly impacted how people were engaged with their organization and its quality of work. It impacted the working mode, viz., work from home, flexible hours, and hybrid working for skilled workers and executives. More tech workers in India have started moonlighting despite the disapproval of their employers and managers. The concept of employee loyalty, value system and ethics has undergone changes and they have reassured themselves with the western model of employment where such moonlighting became an acceptable industry norm. An ethical dilemma arises in the mind of the employers when their full-time professionals and employees started moonlighting in the same industry and at the cost of the companies resources and time. It is considered unethical and a case of loss of confidence which may attract penal action. The present study provides a valuable understanding about the concept of moonlighting and multiple job-holding and its changing dimensions in the Indian IT industry.
DEVELOPMENT OF A FACIAL RECOGNITION SYSTEM USING PYTHON
Authors: Pedroso Branches Romulo , Pimentel Santarem Franciele , Mark Lobo de Oliveira Jean , Augusto da Paz Elleres Pablo
Published: November 2023

This article explores the evolution of facial recognition in the field of computer vision, focusing on the development of a facial recognition system using Python. The text begins by highlighting the growing importance of this technology in various areas, from security to retail, driven by the advancement of machine learning algorithms and computational power. Facial recognition not only offers additional layers of authentication and authorization, but also transforms the user experience in industries such as healthcare and entertainment. The article details fundamental concepts, image processing techniques, and machine learning algorithms essential to the development of the system. The agile methodology, combining ORK, Canva, and Scrum, is adopted to ensure efficiency and adaptability during the development process. The results reveal a robust and effective algorithm, highlighting its impact on the security, retail, and personal technology industries. The text also emphasizes ethical and privacy considerations, which are essential for the responsible integration of this innovative technology.
THE RELATIONSHIP BETWEEN THE COFFEE INTAKE AND THE WORK PERFORMANCEOF COFFEE-DRINKING TEACHERS: A CORRELATIONAL STUDY
Authors:   National University Philippines, Montessori De Sagrada Familia, Inc., P. Pineda Girlie , Rochelle G. Hilario Jonah ,   National University Philippines, Montessori De Sagrada Familia, Inc.
Published: November 2023

Coffee is one of the most consumed drinks all over the world. People consume approximately a million bags of coffee in a day. Depending on the drinkers age, amount of consumption, and the like, coffee is consumed for its various effects aside from its taste and aroma. Additionally, many people drink coffee because of different factors. The caffeine content of coffee is said to be a stimulant that could make drinkers more alert and awake. However, it could cause negative influences such as disturbance in ones sleeping patterns. Hence, the primary purpose of this correlational research is to determine the relationship between coffee intake and the work performance of coffee-drinking teachers and the implications of coffee intake to them. Survey questionnaires were distributed including teachers coffee intake profiles and observations. Consequently, the students, co-teachers, and administrators of the respondents were also asked to determine the work performance observations of these respondents. The results showed evident implications of the coffee intake manifested by the teachers. Meanwhile, results showed that there were no significant relationships between the coffee intake and the work performance of the respondents. This could be attributed to the respondents long-term coffee consumption leading to their coffee effects tolerance. Recommendations made for teachers are to drink coffee with prudence due to its long-term impact on health. Recommendations were made for future researchers to choose respondents who are new coffee drinkers to ensure that there will be no coffee intake tolerance that could impact the results of the study.
ACUTE DISSEMINATED ENCEPHALOMYELITIS FOLLOWING VARICELLA INFECTION
Authors:   Pediatrics Department A Mother and Child Hospital Center Hospitalier Mohammed VI, Marrakech, Morocco., Benghazala S. , Taher F. ,   Pediatrics Department A Mother and Child Hospital Center Hospitalier Mohammed VI, Marrakech, Morocco., Mrhar S. ,   Pediatrics Department A Mother and Child Hospital Center Hospitalier Mohammed VI, Marrakech, Morocco., Fakiri K.EL ,   Pediatrics Department A Mother and Child Hospital Center Hospitalier Mohammed VI, Marrakech, Morocco., Rada N. ,   Pediatrics Department A Mother and Child Hospital Center Hospitalier Mohammed VI, Marrakech, Morocco., Draiss G. ,   Pediatrics Department A Mother and Child Hospital Center Hospitalier Mohammed VI, Marrakech, Morocco., Bouskraoui M. ,   Pediatrics Department A Mother and Child Hospital Center Hospitalier Mohammed VI, Marrakech, Morocco.
Published: November 2023

Inflammatory demyelinating disease affecting the central nervous system(CNS). Early treatment is the key to neurological recovery. We reportthe case of a 4-year-old girl who developed cerebellar ataxia one week after a varicella rash. Cerebral MRI revealed bilateral lesions of the white matter in favor of ADEM. Corticosteroid boluses associated with antiviral treatment were administered and resulted in a remarkable clinical improvement. Long-term follow-up is essential for assessing prognosis.
BILATERAL ELASTOFIBROMA OF THE SCAPULA: A CASE REPORT AND LITERATURE REVIEW
Authors:   Orthopedics Department, Collage of Medicine, King Saud University, Riyadh, Saudi Arabia., Aljassir MD. MSc. FRCSC Fawzi , Alageel MBBS Musab ,   Orthopedics Department, Collage of Medicine, King Saud University, Riyadh, Saudi Arabia., Almuhanna MBBS Abdulaziz ,   Orthopedics Department, King Saud Medical City, Riyadh, Saudi Arabia.
Published: November 2023

Introduction:Elastofibromas are ill-defined, benign lesions typically located on the inferior pole of the scapula underneath the serratus anterior and latissimusdorsi.Elastofibromas are treated surgically to relieve pain and patients can regain range of motion in the shoulder. Bilateral scapulaelastofibromas are extremely rare. To the best of our knowledge, this report details the first case of symptomatic bilateral elastofibromas of the scapula in a patient younger than 60 years of age. Case presentation: A 51-year-old woman with diabetes mellitus and hypertension presented to the orthopedic clinic at King Saud University Medical City in August 2022. The patient had begun experiencing dull bilateral shoulder pain, with swelling which began five years. Patient denied any constitutional symptoms. A physical examination revealed a 7 8cm mass on the right scapula and a 6 7cm mass on the left scapula. There was no tenderness over the mass, and in both shoulders, the range of motion was restricted. MRI of both shoulders revealed increased intensity in the T1 andT2 axial and coronal cuts (Figures 3A-D). The right-side mass was 8 9cm, and the left-side mass was 8 7cm. Excisional biopsy is done for both lesions in separate time and sent for histopathology which confirmed the diagnosis of Elastofibroma. Also, the patient regains her full functionality of both shoulders, and the pain was resolved Conclusion: Elastofibroma can present on both shoulders, lead to chronic shoulder pain and decrease the functionality of the shoulders. Elastofibroma should be diagnosed by MRI and treated surgically by excision to improve the pain and functionality.
SINGLE CROSS-BORDER FREE ROUTE AIRSPACE CONCEPT IN THE ASEAN REGION
Authors:   Air Traffic Management Research Institute, Nanyang Technological University, Singapore., Athota Srinivas , Tominaga Koji ,   Air Traffic Management Research Institute, Nanyang Technological University, Singapore., Zeng Yixi ,   Air Traffic Management Research Institute, Nanyang Technological University, Singapore., N. Duong Vu ,   Air Traffic Management Research Institute, Nanyang Technological University, Singapore.
Published: November 2023

Single Cross-Border Free Route Airspace (FRA) represents the ultimate long-term idealistic routing rules allowing airspace users freely plan a route in en-route airspace, which is not immediately possible from the administrative and technological point of view. In Single Cross-Border FRA, the whole ASEAN airspace is treated as a single-large FRA where all 12 Flight Information Regions (FIRs) implement FRA, with direct routing between the entry (horizontal entry into FIR or end of Standard Instrument Departure Route, SID) and the exit (horizontal exit from FIR or beginning of Standard Arrival Route, STAR). Single Cross-Border FRA is the most fuel-efficient reference that we could ever reach in the future.All otherhypothetical routing rules fall between the Single Cross-Border FRA and those hypo-thetical routing rules in terms of fuel efficiency. In this paper, we described the potential in fuel efficiency (or benefit achievement scaling) with refer-ence to this ultimate basic fuel requirement and scaled the excess fuel with different routings. We evaluated the fuel burn with a fast-time simulation (FTS) in 12 different scenarios (3 traffic volume levels Ã— 4 routing scenarios). As for the traffic volume scenarios, we simulated 1-day of commercial ASEAN flight schedule data of 3 traffic volume levels (100%, 150%, and 200% of pre-COVID19 traffic volume). As for four routing scenarios with increasing levels of directness: conventional Air Traffic Service route network (ATS) (R1), hypothetical Several-Small FRA route network (R2), Single Cross-Border FRA route network with Danger Areas (R3) and Single Cross-Border FRA network without Danger Areas (R4). Results showed that flight time, fuel burn, and distance travelled were less in R2, R3, and R4 than in R1. There was an average difference of 2.2% in flight time, 1.9% in fuel burn, and 2.2% in distance travelled from R1 to R4.
REVIEW OF TRICHOMONAS VAGINALISINFECTION FROM (2013-2023) IN GOVERNORATES OF IRAQ
Authors:   Department of Microbiology, College of Medicine, University of Diyala, Diyala, Iraq., Abdulkhaleq Hussein Rawaa , Jasim Shaker Mohammed ,   Department of Microbiology, College of Medicine, University of Diyala, Diyala, Iraq.
Published: November 2023

Trichomonasisis one of the most common sexually transmitted disease(STD) in the countriesmostly for females, caused by a move protozoa parasitic infection called Trichomonas vaginalis (T. vaginalis)and cause vaginal discharge for femalesalsorising of dysuria. Humans are the only recognized infected with thisparasite transmitted via vaginal sexually intercourse. people who infected with nosighs can transmite the trichomonasis to other people. The infection with trichomoniasisgreatly damages the reproductive system,Trichmoniasis has important medical, social , and economical implication. It is reported to be more than 280 million annual cases globally. T.vaginalis holds the distinction of being the only parasite infection transmitted sexually in humans. It is a highly effective disease. The present study aim to throw more light on the epidemiological of T. vaginalis infection. Where,this study article related to the prevalence of T. vaginals among Iraqi people in period from (2013-2023) were studied in different governanceofIraq.These type of epidemiological studies are recommended to assess the epidemiological situation of trichomonasis in the way to implement appropriate control measures where needed.Results of data analysis reveals different rate of infection by this parasite in Iraqi governance.Itconcludesthe variation in parasitic infection rates among studies can be interpreted on the basis of geographical location of Iraqi governorates, size of population, Tourist cities, industrial cities, rate of female/male in population, personal hygiene, education levels. In addition, various sampling techniques and research methodologies, all consider markers could demonstrate the causes for the varies in the data of parasitic infection in different researchs.
PULMUNARY OEDEMA DUE TO PEPPERMINT OIL POISONING : A CASE REPORT
Authors:   Associate Professor, DepartmentofMedicineDr. Ram Manohar Lohia Institute of Medical Sciences, Gomtinagar, Lucknow, UP., Verma Jyoti
Published: November 2023

A case is reported where a patient, after ingestion of Peppermint Oil,developedrespiratory distress, altered sensorium and was in shock on arrival in hospital. Clinically and radiologically, patient appeared to be having acute Pulmonary Oedema.Timely and appropriate measurements like intubation, mechanical ventilation, inotropes, gastric lavage,antibiotics,and antacids helped patient to recover.We present a rare case of pulmonaryoedema following peppermint oil ingestion.
INFANTIL NEUROAXONAL DYSTROPHY: A CASE REPORT
Authors:   Pediatric Neurology Unit, Pediatric Department, Chu Hassan Ii, Fes, Morocco., Moudden S.El , Mkadem K. ,   Pediatric Neurology Unit, Pediatric Department, Chu Hassan Ii, Fes, Morocco., Chaouki S. ,   Pediatric Neurology Unit, Pediatric Department, Chu Hassan Ii, Fes, Morocco., Hida M. ,   Pediatric Neurology Unit, Pediatric Department, Chu Hassan Ii, Fes, Morocco.
Published: November 2023

Infantile neuroaxonal dystrophy is a rare, hereditary neurodegenerative disease that begins before the end of the second year of life, after an interval of normal psychomotor development caused by Biallelic mutations in the PLA2G6 gene in the most of cases. It is characterized by progressive motor and cognitive deterioration leading to a bedridden state and death before the end of the first decade. We report the case of a two and a half year patient who showed psychomotor regression with ophthalmological damage, truck hypotonia and impaired visual contact as the main neurological signs. Infantile neuroaxonal dystrophy is a rare and serious disease in children with a risk of generally fatal complications, but it remains a preventable disease thanks to genetic counselling.
A QUESTIONNAIRE BASED SURVEY TO ASSESS EDENTULOUS PATIENTS KNOWLEDGE ABOUT DENTURE HYGIENE
Authors: M. Solanki Kinjal , Pankaj Panchal Pankti , B. Patel Ina , S. Shukla Param , Samir Shah Rujul
Published: November 2023

Aims & Background:The aim of the study is to assess the knowledge of edentulous patients on denture hygiene. Materials and Methods:Total100 patients wearing full dentures were selected in thissurvey after considering inclusion and exclusion criteria. This study was conducted using exploratory questionnaire technique. Total 16 questions were selected and verified by dental professionals and subject experts (Prosthodontists). These 16 questions were based on maintaining denture hygiene. Statistical analysis was carried out after collecting all the data. Results:After evaluation of 100 individuals, the majority of patients wore denture during day for longer time.Most of them were utilised to store their denture in a plastic box filled with water. The majority of patients were cleansing their dentures using water and brush more than once every day. Survey revealed decreased frequency of cleaning and increased intake of tea/coffee/tobacco can cause denture staining. According to survey knowledge of patients regarding denture hygiene was lacking due to improper instructions given by dentist or dental hygienist. Result showed significant correlation between frequency of cleaning and oral disease related to denture, which signify that improper cleaning can cause fungal growth and other oral disease related to denture. Conclusion:This survey revealed that patients cleaned their dentures mechanically but improperly explained by dentist or dental hygienist. As a dentist we should encourage and provide proper knowledge to the patient regarding different cleansing and storage technique. The dentist must take regular follow up.
TOURISM NETWORK AND INFORMATION AND COMMUNICATION TECHNOLOGIES IN THE SOUTH OF MOROCCO: A CASE STUDY
Authors:   University of Ibn Zohr Agadir, Morocco., Loux Kamal
Published: November 2023

With the arrival of internet, business rivalry has become increasingly violent. The use of information technologies has become a strategic alternative for small business companies. Adopting websites and social media is considered as the perfect step for the survival of small companies working in tourism. In addition to this, technology has an impact on the management system of the organisation, guaranteeing the improvement of productivity, performance and competitiveness of small companies. The literature review demonstrates that the appropriation of technologies based on intentions and perceptions makes companies more competent. Our paper aims to verify the level of use and appropriation of the technology by the rural tourist companies owners affiliated to the Rural Tourism Development Network (RDTR) located in the south of Morocco. We look at how the owners of these small rural tourist companies, based in this area, perceive the technology, to understand the sense of ownership of Information and Communication Technologies within these companies and to analyse the integration of the web strategy in their organisation. We have selected a mixed analysis method on a sample of 30 companies members of RDTR, south of Morocco.
DYNAMIQUE DOCCUPATION DES TERRES ET TRANSFORMATIONS DES ECOSYSTEMES AUTOUR DES USINES DEGRENAGE DE COTON DE LA SOFITEX DES VILLES DE BOBO DIOULASSO ET DE BANFORA AU BURKINA FASO
Authors:   Centre National de la recherche Scientifique et Technologique /Institut de lEnvironnement et de Recherches Agricoles (INERA/CNRST), Laboratoire Sol-Eau-Plante, BP 910, Bobo Dioulasso, Burkina Faso., P.K. Gomgnimbou Alain , S.W. Kabore Arnaud ,   Centre National de la recherche Scientifique et Technologique /Institut de lEnvironnement et de Recherches Agricoles (INERA/CNRST), Laboratoire Sol-Eau-Plante, BP 910, Bobo Dioulasso, Burkina Faso.,   Ministere de lEnvironnement, de leau et de lAssainissement, Direction generale de la Preservation de lenvironnement, Ouagadougou, Burkina Faso.,   Centre National de la recherche Scientifique et Technologique /Institut de lEnvironnement et de Recherches Agricoles (INERA/CNRST), Station de Recherche de Saria, Koudougou, Burkina Faso., Sigue Hamade ,   Centre National de la recherche Scientifique et Technologique /Institut de lEnvironnement et de Recherches Agricoles (INERA/CNRST), Station de Recherche de Saria, Koudougou, Burkina Faso., W. Ouedraogo Osee ,   Centre National de la recherche Scientifique et Technologique /Institut de lEnvironnement et de Recherches Agricoles (INERA/CNRST), Laboratoire Sol-Eau-Plante, BP 910, Bobo Dioulasso, Burkina Faso.,   Ministere de lEnvironnement, de leau et de lAssainissement, Direction generale de la Preservation de lenvironnement, Ouagadougou, Burkina Faso., Y. Some Corentin ,   Departement de Geographie, Unite de Formation et de Recherche en Lettres et Sciences Humaines, Universite Norbert ZONGO, Koudougou, Burkina Faso Laboratoire de Recherche en Sciences Humaines et Sociales (LABOSHS), Universite Norbert ZONGO, Koudougou, Burkina Faso.
Published: November 2023

The study concerns the analysis of the dynamics of land occupation around the factories Bobo 1, Bobo 2 and Banfora 1, Banfora 2 at Burkina Faso. The types of land use in these areas were analyzed in order to understand the changes resulting from the industrial activities, urbanization and other factors. The tools used are Envi 5.3 for the processing of satellite images, the Excel table for the processing and production of graphics and ArcGIS 10.5 for data mapping. The observed are the conversion of agricultural land into industrial areas, urban expansion and the modification of the natural ecosystem. The areas occupied by residential areas increased on average by 615.76 hectares/year between 1986 and 2021 around the Banfora factories and by 1885.41 hectares/year between 1976 and 2021, for the Bobo-Dioulasso units. The comparison between the Bobo 1, 2 and Banfora 1, 2 factories revealed similar but also distinct patterns of land cover change. The study contributed to a better understanding of the dynamics of land use change and provided information to guide urban planning policies, industrial development strategies and environmental preservation initiatives in these two cities.
THE EFFECT OF ONLINE DELIVERY SERVICES ON THE PROFITABILITY OF SMALL-SCALE FOOD SERVICES IN GENERAL SANTOS CITY
Authors:   Mindanao State University Graduate School General Santos City, Philippines., Joy Llanos-Bedano Citizen
Published: November 2023

The study aimed to know the effect of the online delivery services on the profitability of small-scale food services in General Santos City. (1) The study concludes that the effect of online delivery services on the profitability of small-scale food services is strong and high. (2) The online delivery platform most employed by the respondents is the new delivery service representing 63%. (3) The small-scale food services are profitable. (4) There is a significant relationship between online food delivery and profitability of the small-scale food services in General Santos City.
THE ROLE OF SUSTAINABLE LEADERSHIP IN IMPLEMENTING SDGS:GREEN INNOVATION STRATEGY (GIS) : STRATEGY TRANSFORMATION IN ORGANIZATIONAL SUSTAINABILITY
Authors:   Marini Purwanto, Business Faculty, Catholic Widya Mandala University Surabaya., Purwanto Marini , Arumsari Agung Deatri ,   Deatri Arumsari Agung, Business Faculty, Catholic Widya Mandala University Surabaya., Adjeng Erwita Monica ,   Monica Ajeng Erwita, Business Faculty, Catholic Widya Mandala University Surabaya.
Published: November 2023

This research aims to analyze whether sustainable leadership influences sustainable performance and if so, whether this influence is mediated by green innovation strategy.The design/methodology of this research is quantitative research that uses partial least squares structural equation models (PLS-SEM) to test hypotheses. Using the survey method, data measurement was carried out using an online questionnaire. A total of 56 hospital managers in Surabaya participated in this research. A mediation research framework was developed to investigate the mediating role of green innovation strategy on the relationship between sustainable leadership and sustainable performance .Findings - Research results show that sustainable leadership influences sustainability performance with the full mediation of green innovation strategy . Further analysis reveals that sustainable leadership influences green innovation strategy and green innovation strategy influences sustainability performance .The limitations of this research are that it focuses on the hospital services sector in Surabaya, East Java, Indonesia, it requires care in generalizing the research results and this method uses surveys which are often criticized for being potentially biased.Practical implications - These findings provide implications for a more comprehensive understanding of hospital administrators, especially in Surabaya, the important role of sustainable leadership , green innovation strategy in improving sustainability performance .Social implications - The health sector has an important role in community welfare. This research provides a general model for improving community welfare through increasing sustainability performance , by understanding the role of sustainable performance and green innovation strategy.
PIRAEUS PORT AND CITY: A COMPREHENSIVE ANALYSIS OF CORRELATIONS AND DEPENDENCIES
Authors:   School of Rural and Geoinformatics Engineering, National Technical University of Athens, Greece., Koumparakis G. , Margaritis M. ,   Department of Civil Engineering, University of the Peloponnese, Greece., Atzemi M. ,   Department of Civil Engineering, University of the Peloponnese, Greece., Makedonas M. ,   School of Rural and Geoinformatics Engineering, National Technical University of Athens, Greece.
Published: November 2023

Background:The Piraeus city-port area constitutes one of the most important economic hubs in Greece, the largest port in the country. This study focuses on the examination of the city-port, exploring whether it can be a harmonious or a rivalry relationship, considering several economic and technical aspects of the two entities. Aim: This study seeks to assess the economic impact of the port on the city and vice versa by examining the regression between the macroeconomic data of the Piraeus region and the economic data of the Piraeus Port Authority. Methodology:Data from the annual financial balance sheets of the Piraeus Port Authority and data for the macroeconomic indicators of the city for the years 2010 to 2020 were used for statistical analysis. Linear regression models were employed for this analysis, using the statistical program IBM SPSS Statistics. Conclusion:The results indicate significant relations and dependencies between the two data sets, highlighting the substantial contribution of the port to the local economy, and vice versa.
Development and evaluation of filter for canal water potability
Authors: Tiwari V. , Singh J. P. , Sahota P. , Singh N. N. , Singh K.
Published: November 2023

A low-cost portable water filter having a capacity of 15 l for an average small family size was designed, developed, and fabricated for canal water potability. The volume and thickness of filter media were computed and found to be 4,544 cm3 and 5.6 cm, respectively. The provision for injection of sodium hypochlorite solution was made for the removal of bacterial contaminants and calibrated as 1.5 mL for 15 l of water to maintain the required level of residual chlorine content (2–5 ppm) which was supplied through the pumping unit. The adsorbed contaminants on the filter media could be removed by placing it in 3 l of boiled water for 2 min. The experiment was conducted to determine the settlement duration of suspended solids in canal water and found to be 8 h, thereafter allowing it for filtration. The performance of the developed filter was evaluated by analyzing water quality parameters of the canal water before and after filtration. The values of biological oxygen demand (BOD), chemical oxygen demand (COD), MPN, TDS, pH, and residual chlorine of filtered water were found to be within the permissible limit. The cost of the developed filter was estimated to be INR 1,300 which is economically viable, technically feasible, and easily portable.