bluuebunny/crossref_metadata_2025 huggingface dataset:
On a class of nonlinear nonlocal fractional differential equations
Authors:   ", FAZLI HOSSEIN ,   HOHAI UNIVERSITY,  STATE KEY LABORATORY OF HYDROLOGY-WATER RESOURCES AND HYDRAULIC ENGINEERING,  COLLEGE OF MECHANICS AND MATERIALS, CHINA", SUN HONGGUANG ,   "HOHAI UNIVERSITY,  STATE KEY LABORATORY OF HYDROLOGY-WATER RESOURCES AND HYDRAULIC ENGINEERING,  COLLEGE OF MECHANICS AND MATERIALS, CHINA", AGHCHI SIMA ,   "HOHAI UNIVERSITY,  STATE KEY LABORATORY OF HYDROLOGY-WATER RESOURCES AND HYDRAULIC ENGINEERING,  COLLEGE OF MECHANICS AND MATERIALS, CHINA", NIETO JUAN J. ,   "UNIVERSIDAD DE SANTIAGO DE COMPOSTELA,  DEPARTAMENTO DE ANÁLISIS MATEMÁTICO, ESTADÍSTICA Y OPTIMIZACIÓN AND INSTITUTO DE MATEMÁTICAS"
Published: October 2021

We investigate the existence of extremal solutions for a class of fractional differential equations in the area of fluid dynamics. By establishing a new comparison theorem and applying the classical monotone iterative approach, we establish sufficient conditions to ensure the existence of the extremal solutions and construct twin convergent monotone explicit iterative schemes. Generalized nonlinear nonlocal Bagley-Torvik equation and generalized Basset equation with nonlinear source functions are some special cases of our discussed problem.
Visitors' Motivation to Attend the Festival of Edible Flowers
Authors: Kwiatkowski Grzegorz , Kurdyś-Kujawska Agnieszka , Janiszewska Dorota , Ossowska Luiza
Published: October 2021

This article examines participants' motivation to an edible flowers festival and their diversification in terms of sociodemographic characteristics. Sixteen motives for participating in the festival were empirically tested and presented in four motivational dimensions. The data were
collected during the 5th Edible Flower Festival in Poland in 2020 using a questionnaire. The results show that the most common motive for participating in a culinary event was the need for socialization. In contrast, the need to experience new culinary discoveries/experiences was slightly
less critical. The findings also show significant differences in the participants' motivational dimensions due to sociodemographic characteristics. Women more often participate in events with a high motivation to escape from the routine of everyday life and cultural exploration. Younger respondents
were more often motivated by searching for culinary novelties, and older respondents were motivated by cultural exploration and escaping from daily routine. For visitors accompanied by family members, the priority was socialization and escape from routine. In contrast, those accompanied by
acquaintances/friends indicated a cultural exploration and encountering new culinary experiences more often. The study results may provide a better understanding of the participants of a culinary festival, increase the effectiveness of marketing and promotional activities, and thus increase
the satisfaction of participants in subsequent events.
Peran Keluarga Untuk Menciptakan Lingkungan Belajar Di Rumah
Authors: Sastrawan Ketut Bali
Published: October 2021

The Covid-19 pandemic has had a huge impact on the world of education. Government policies that implement learning from home open up public insight about the role of the family in education. This research is a qualitative descriptive research. The role of the family in creating a good learning environment for children is very large. Families, especially parents, play a role in creating a learning environment for children by developing a sense of affection in the family, building communication with children and parents being an example for children. Discipline also needs to be developed in a child. The Hindu community home environment can be a good learning environment for Hindu children if used properly. The architectural patterns of Balinese houses are filled with symbols that have certain meanings in Balinese society. Religious symbols influence the life of Hindu society and create a learning environment for children.
Diferensiasi Tingkat Upacara Pawintenan Kepemangkuan Di Lombok
Authors: Yudhiarsana I Made Agus
Published: October 2021

The pawintenan ceremony has levels based on the implementation of the Dewa Yadnya or Rsi Yadnya ceremony. The types of pawintenan are Pawintenan Sari, Pawintenan Gede, Pawintenan Mapedamel Ganapati, Pawintenan Mapedamel Dasa Guna, and Pawintenan Samskara Ekajati or Panca Rsi, while the public is still confused in determining the level of the pawintenan ceremony, especially the pawintenan kepemangkuan. This research focuses on studies related to the level of the ceremony and the process of implementing the pawintenan pemangku or pinandita ceremony in Lombok. This study aims to provide an understanding of the level of the pawintenan ceremony of pemangku for the public in Lombok. This study uses descriptive research with a qualitative approach with data collection techniques using observation, interviews and documentation. Pemangku or pinandita are people who have gone through the pawintenan ceremony until Adiksa Widhi, but have not gone through the procession at the site and amati aran or changed names. The levels of pawintenan are divided based on the profession of the pawintenan Sastra or Saraswati, the pewintenan Sari or Pemangku, the pawintenan Dalang, the pawintenan  Tukang, and the pawintenan Mahawisesa. The pawintenan ceremony based on the results of research on the Pemangku or Pinandita temples which are included in the temple Mataram City shows that the Pinandita or Pemangku groups the levels of the Pawintenan Pemangku ceremony in Lombok, especially in the city of Mataram into the three levels of the pawintenan ceremony are pawintenan alit, pawintenan madya and pawintenan ageng or agung. This division is based on the duties and responsibilities of pemangku or Pinandita. Which includes pawintenan alit is Pawintenan Sari atau saraswati, Pawintenan Madya is Pawintenan Pemangku, and Pawintenan Agung is Pawintenan Jero Gede or Bhawati, as the highest stage of the Ekajati ceremony in Lombok.
Diagnostic accuracy and limitations of non-invasive tests in patients with metabolic-associated fatty liver disease
Authors: Sánchez Torrijos Y , Lucena Valera A , Ampuero Herrojo J
Published: October 2021

La incidencia de la enfermedad del hígado graso asociada al metabolismo (MAFLD) ha aumentado en los últimos años debido al estilo de vida actual. La biopsia de hígado sigue siendo la herramienta estándar de oro para detectar y estadificar MAFLD. Por otro lado, se están desarrollando múltiples biomarcadores y pruebas no invasivas para superar las limitaciones de la biopsia hepática, incluidos el costo y la invasividad. Las pruebas no invasivas se centran principalmente en la esteatosis y, en particular, en la fibrosis hepática y se pueden clasificar en pruebas patentadas y no patentadas. Si bien hepatic steatosis index y fatty liver index son las pruebas más comunes utilizadas para la detección de esteatosis, Hepamet Fibrosis Score, NAFLD fibrosis score, FIB-4, OWLiver®, y ELF® son las más utilizadas para la fibrosis hepática. Sin embargo, las pruebas no invasivas también tienen limitaciones que conviene resaltar ya que sus resultados podrían verse afectados por la presencia de diabetes, obesidad o por edades extremas que podrían dar lugar a falsos positivos o negativos. Para maximizar la precisión de los tests no invasivos, se han propuesto diferentes combinaciones integradas en algoritmos escalonados. Esta revisión tiene como objetivo destacar las fortalezas y limitaciones de dichos tests para detectar y estadificar MAFLD.
Oral mucositis as a complication of antitumor treatment in patients with local – advanced head and neck cancer: narrative review.Oral mucositis as a complication of antitumor treatment in patients with local – advanced head and neck cancer: narrative revi
Authors: Radzhabova Zamira , Kotov Maksim , Sereda Ol`ga , Dadasheva Umuhanum , Pudina Anastasiya , Chizh Grigorii
Published: October 2021

Despite our successes in understanding of nature appearance of oral mucositis, it still is serious problem for patients that are given antitumor treatment due to local – advanced head and neck cancer. Dangerous of oral mucositis` related with antitumor treatment in that patients consist of decrease quality of patients` life and increase risk of life-threatening complications. We were tasked to estimate of efficacy and feasibility of offered in the world now treatment methods for oral mucositis related antitumor treatment for cancer of head and neck and reflect modern condition of this problem. We used systems of medical date ScopusGoogle Scholar, PubMed and studied modern findings about factors of appearance and flowing this pathological condition in patients that are given of antitumor treatment and also were studied possible ways for prevention and management in oral mucositis. Now there are exist many different types of prevention and treatment of oral mucositis and they all are described in this article. In some cases, use of this methods of management allow to reach decrease of risk of life-threatening complications and increase of life patients` quality but a lot of them are symptomatic, palliative. It makes look for novel therapeutic strategies for management for that patients. For making decisions about intervention, we have to estimate step of hard of that condition in patients which influence to ability to speak and intake of meal per month in patients. All actions are directed to increase of tolerable antitumor treatment, decrease of risks related with this treatment.
The state of cancer care in Russia: malignant neoplasms of the skin (C44). Typical mortality, median survival, observed and relative survival, taking into account the stage of the disease. Population-based research at the federal district level
Authors: Merabishvili Vahtang
Published: October 2021

In the previous article, we presented an analysis of the prevalence and quality of registration of patients with malignant neoplasms of the skin (C44) in Russia and the North-Western Federal District, showed the quality of accounting and revealed the features of the dynamics of localization and histological structure.
In this report, for the first time in Russia, our attention is focused on the nature of evaluating the effectiveness of anti – cancer measures based on the main criterion-calculating the survival rates of patients with malignant skin neoplasms at the level of the North-Western Federal District, whose level of "rough" and standardized indicators of morbidity and mortality of the population practically does not differ from the average Russian one.
Calculations of all types of survival rates of patients with malignant skin neoplasms (C44) at the federal district level became possible after the organization in February 2019 of a single database (DB) of the cancer registry of the North-Western Federal District, numbering more than 1 million cases of ZNO, including more than 20,000 with malignant melanoma of the skin (2.0%).
The created database allows for in-depth development of the dynamics of the localization and histological structure for any part of the localization structure (lip, ear, trunk, etc. parts of the body), which is not available for conducting on the basis of state reporting forms formed before receiving all the information characterizing the state of the oncological service, not to mention that when analyzing the activities of the oncological service, databases of population cancer registers are not used and calculations of the main criterion for its assessment – the calculation of patient survival.
Changes in the concentration of EGFR-mutated plasma DNA in the first hours of anti-EGFR therapy allow the prediction of tumor response in patients with EGFR-driven lung cancer
Authors: Martianov Aleksandr S , Moiseenko Fedor , Zhabina Albina , Sokolova Tatyana , Beluhin Sergey , Laidus Tatiana , Kholmatov Maxim , Turin Vladislav , Volkov Nikita , Kuligina Ekaterina , Yanus Grigoiy
Published: October 2021

This study aimed to analyze changes in the plasma concentration of EGFR-mutated DNA occurring immediately after the start of therapy with EGFR tyrosine kinase inhibitors (TKIs). The study included 30 patients with EGFR mutation-driven non-small cell lung cancer (NSCLC).  Serial plasma samples were collected before intake of the first tablet and at 0.5, 1, 2, 3, 6, 12, 24, 36 and 48 hours after the start of the therapy. EGFR-mutated plasma DNA (EGFR+ ctDNA) was detectable at diagnosis in 25 out of 30 study participants. There were different patterns of changes of the amount of circulating tumor DNA, i.e., the consistent decline of ctDNA content, or continuing increase of the number of circulating EGFR mutant copies, or alternating spikes and drops in the ctDNA concentration. Correlation with the disease outcome was observed only for the measurement performed at 48 hours. Twelve (50%) out of 24 informative patients showed >25% reduction of the ctDNA content at 48 h time point; all these patients demonstrated disease control after 4 and 8-12 weeks of therapy. The remaining 12 individuals showed either stable content of circulating EGFR+ DNA (n = 5) or the elevation of ctDNA concentration (n = 7). 10 of 12 patients with elevated or stable ctDNA level achieved an objective response at 4 weeks, but only 5 of 10 evaluable patients still demonstrated disease control at 8-12 weeks (p = 0.014, when compared to the group with ctDNA decrease). The decline of the amount of circulating EGFR mutant copies also correlated with longer progression-free survival (PFS; 14.7 months vs. 8.5 months, p = 0.013). Conclusion: Monitoring of plasma EGFR-M+ concentration within the first hours of the TKI therapy may be used as an immediate predictor of tumor response to the treatment.
Endoscopic submucosal dissection for early colorectal cancer
Authors: Sidorova Aleksandra , Klimenko Vasiliy , Sherbakov Aleksandr , Tkachenko Oleg , Iaikova Olga , Grinkevich Marina , Petrik Iurii , Ivko Olga , Muravceva Anastasiya
Published: October 2021

The aim of the study was to evaluate the effectiveness of endoscopic submucosal dissection for early colorectal cancer. From 2014 to 2020 at the N.N. Petrov National Medical Research Centre of Oncology, 165 patients with stage cTis-T1N0M0 colorectal cancer were treated by endoscopic submucosal dissection, including 103 women and 62 men aged from 29 to 89 years (mean age 64 years). A single block resection was achieved in all cases, regardless of size and location. Intra- and early postoperative complications were observed in 14 (8.4%) patients, there was no postoperative mortality. In the presented study, endoscopic submucosal dissection showed technical success in 100% of cases, with a risk of postoperative complications of 4.2% and appeared curative in 80.7% of cases. Thus, this technique can be recommended for the treatment of early colorectal cancer due to its high efficiency and safety.
Tlustý kruhový peníz se lvem / Thick round coin with lion image
Authors: Gregor Pavel
Published: October 2021

The author presents an unknown double-sided thick round coin with lion and crown images preserved in a private collection. Based on detailed iconographic and material analyses, and on comparison with the contemporary lion / crown types, the author offers the very likely dating of the coin. It was produced before the reform of George of Poděbrady, i.e. between 1460 and 1469. The coin also documents the fact that the hellers of George with crown in pearled circle could not have been struck after the reform in 1469, but – very likely – they had been also produced before the reform.
Antoninus Pius – císař reprezentující „zlatý věk“ římského impéria / Antoninus Pius – Emperor representing the ‘Golden Age’ of the Roman Empire
Authors: Petráň Zdeněk
Published: October 2021

The coins of the Roman Emperor Antoninus Pius struck in the mid-2nd century AD are very popular among collectors because they practically very often appear in all their denominations, and the numismatic trade offers a large scale of all coin types of this ruler. Also the personality of this Emperor representing the ‘Golden Age’ of the Roman Empire is extraordinary. There were no destructive wars during his 23-year-long rule, and the Roman Empire was economically significantly flourishing because of the political peace times. This should change in time of his successor and son-in-law, a successful warrior and ‘philosopher on throne’ – Marcus Aurelius.
Vzácná varianta republikánského denáru typu RRC 222/1 / A rare variety of the Roman Republican denarius of the RRC 222/1 type
Authors: Vacinová Lenka
Published: October 2021

An extremely rare variety of the Roman Republican denarius of the RRC 222/1 type has been identified recently in the numismatic collection of the National Museum in Prague. The article analyses its iconography in a broader context of the Greek and Roman coinages as well as other visual art styles emphasising importance of consistent differentiation between the goddesses Diana and Luna that are frequently confused one with another even in the scholarly literature.
Depoty uložené v kutnohorském muzeu / Coin hoards preserved in the Kutná Hora (Kuttenberg) museum
Authors: Kremla Josef
Published: October 2021

The Bohemian Museum of Silver in Kutná Hora (Kuttenberg) has recently eleven coin hoards and seventeen single finds in its numismatic collection. Some 20 years ago, Z. Petráň gave a lecture about them during the numismatic colloquy in Pardubice. This article should correct some inaccuracies and adds new information about the coin hoards preserved in the Kuttenberg museum.
Schäden erkennen und vermeiden
Authors: Bose-Munde Annedore
Published: October 2021

Die Schadensvermeidung und -verhinderung sowie der fachliche Austausch mit Experten aus Industrie, Werkstoffprüflaboren und Wissenschaft steht im Fokus der VDI-Jahrestagung Schadensanalyse. Wasserstoff in metallischen Bauteilen sowie die mediale und klimatische Beanspruchung von polymeren Produkten waren Schwerpunkte der diesjährigen Veranstaltung.
Design of a Pitch Controller for a Wind Turbine Using Hybrid Mean-Variance Mapping Optimization
Authors: Behera Sasmita , Sahoo Subham
Published: October 2021

A variable-speed wind energy conversion system (WECS) has the advantage of extracting more power from the time-varying wind. To achieve this, the pitch angle is controlled to maintain the speed of the turbine and hence the generated power at a constant level, while reducing mechanical stress on the turbines. In this work, a proportional-integral (PI) controller is used for pitch angle control. The optimal PI control gains and  are tuned by the hybrid mean-variance mapping optimization (MVMO-SH) technique, particle swarm optimization (PSO), and a genetic algorithm (GA). Different fitness evaluation criteria and optimization techniques are compared, and the performances of optimal controllers presented in the time domain. The results reveal that MVMO-SH achieves the minimum error criteria within a shorter time. The optimal controller design gives an error of less than  in the region for which it is tuned. The performance of the optimal PI controller is designed for one operating condition in different cases of wind gust, random variation of wind, and disturbance from the grid side to mitigate line to ground fault. The performance of the controller is shown to be satisfactory in all the cases studied.
Virtual Inertia Design Procedure for Energy Storage Systems to Increase Frequency Response Performance in Microgrids
Authors: Suphahatthanukul Gorn , Chirapongsananurak Pisitpol , Hoonchareon Naebboon
Published: October 2021

The frequency instability caused by low system inertia is a common problem for small power systems such as microgrids since it can lead to stepping load shedding and generation tripping when disturbances occur. To alleviate the problem, this paper proposes a procedure for the virtual inertia design of an energy storage system (ESS) using the linear quadratic regulator (LQR) technique. The advantage of this proposed procedure is that it can separately manipulate the frequency response performance indices: the nadir and rate of change of frequency (RoCoF). The results confirm that the proposed procedure enables the microgrid to maintain frequency stability and avoid unnecessary load shedding whether operating in the grid-connected or islanding mode.
Sustav upozorenja na opasne vremenske pojave u sektoru za vremenske i pomorske analize i prognoze Državnoga hidrometeorološkog zavoda
Authors: Renko Tanja , Mikuš Jurković Petra , Kalin Lovro , Hojsak Tomislava , Mokorić Marija , Kozarić Tomislav
Published: October 2021

Upozorenja na opasne vremenske pojave vrlo su bitna za zaštitu života i imovine građana Republike Hrvatske (RH) i sukladno s tim izdavanje upozorenja jedan je od primarnih zadataka Državnoga hidrometeorološkog zavoda (DHMZ), koji ima i isključivu nadležnost za njihovo izdavanje. DHMZ sustavno i kontinuirano razvija kvalitetne informacije na opasne vremenske pojave te je sustav upozoravanja doživio mnoge preinake posljednjih godina, a posebnu ulogu u tome imao je razvoj interneta i tehnologija kojima se informacije mogu vrlo brzo prenositi.
U procesu izdavanja upozorenja i obavješćivanja javnosti DHMZ mora komunicirati i surađivati
sa svim službama i partnerima zaduženima za sigurnost građana RH.
U ovom je radu dan pregled sustava DHMZ-a za izdavanje upozorenja na opasne vremenske
pojave, od standardnih operativnih postupaka, razvoja sustava koji je posljednjih nekoliko godina bio vrlo intenzivan, do objašnjenja konačnog produkta, odnosno informacije koja je dostupna svim građanima RH na mrežnim stranicama DHMZ-a. Također su prikazane mnoge
statističke značajke upozorenja izdanih u razdoblju od 2009. do 2018. godine, način verifikacije
pojedinih upozorenja, a jedno poglavlje posvećeno je i zaštiti od požara raslinja, odnosno ulozi
DHMZ-a u provedbi mjera zaštite od požara od interesa za RH.
Health risk of radon exposure
Authors:   National Agency for Public Health, ABABII Aurelia ,   “Nicolae Testemitanu” State University of Medicine and Pharmacy
Published: October 2021

Introduction. Radon is a chemical element of increased interest to the scientific community due to its implications in the etiology of bronchopulmonary cancer. Pollution of indoor air with radon causes serious effects on health, due to alpha radiation emitted following the process of disintegration into isotopes that together with dust particles, dust enters the alveolar level. Material and methods. This study was based on the analysis of bibliographic sources within the PubMed and Google Scholar platforms. The relevant articles for the study were chosen analogously to the research objectives, interest in publications attesting to the problem of residential radon, its implications in the etiology of lung cancer and the synergism between radon and tobacco. Results. Radon is attributed a significant role in indoor air pollution, has a share of about 50% of total exposure to ionizing radiation and is the second leading cause of death from lung cancer internationally. The synergism between radon and tobacco causes an increased effect in triggering the processes of damage at the cellular level, by disturbing translation and transcription. In the Republic of Moldova, the problem is current; the level of residential radioactivity caused by radon exceeds European and national standards in about half of cases. Conclusions. It is imperative to continuously monitor radon concentrations in the country's homes, set benchmarks, update national rules and implement an effective strategy to reduce the negative effects of radon exposure.
Global health education experience of a multidisciplinary curriculum at Rouen school of medicine, France
Authors:   University Hospital Center, UFR Santé, LADNER Joël
Published: October 2021

Introduction. The interest in Global Health (HG) as an academic discipline has increased in the last decade. The Rouen School of Medicine is one of the first to offer a GH curriculum in France. The objective was to identify the characteristics and profile of students involved in a GH curriculum. Material and methods. In 2016 and 2017, a cross-sectional study was conducted, including enrolled in the GH course: 3rd and 4th year in medicine, midwifes studies and pharmacy. Based on self-questionnaire, data collected were motivations for health studies, investment in humanitarian associations, opinions about the GH topics. Results. A total of 422 students were included; 122 students attended to GH cursus (GH+) and 300 in control group (GH-). The students of the GH+ group were more likely to get involved in a humanitarian association (22.3% versus 6.7%, p<0.001) and to have already taken part in a humanitarian action (20.5% vs 9.3%, p=0.002). GH+ students were more likely to engage in professional practice abroad or in humanitarian medicine (67% versus 38%, p=0.001). Work in vulnerable populations, the impacts of climate change on health are frequent topics in GH+ group. Conclusions. Students enrolled in GH cursus presented a particular profile: predominantly female, open to The World, involved in caritative associations and aware of the importance of interculturality in the care relationship. Integrated training of future health workers is a promising avenue for a better management of effect of sanitary crisis (i.e. pandemic, climate change and health effects, etc.).
PREVIOUS MILITARY PILOTS AND THEIR LATER FATAL CIVIL AVIATION ACCIDENTS
Authors: Laukkala Tanja , Pukkala Eero , Budowle Bruce , Sajantila Antti , Mäntysaari Matti , Huhtala Heini , Vuorio Alpo
Published: October 2021

Military pilots undergo rigorous selection compared with civilian professional pilots because of different operational requirements. There are no studies of military pilots’ subsequent civil aviation careers and fatal pilot aviation accidents. This study focuses on Vietnam War (VW) pilots and subsequent fatal aviation accidents in the U.S from 1965 to 2018. In total nine aviation accidents met the inclusion criteria and are described in detail, including the pilots’ previous civil aviation incidents. The VW pilots were healthy, had valid Medicals and continued to fly in demanding pilot positions after their military careers. Although the data are limited, this study suggests that previous military pilots may differ slightly from other pilots in their subsequent civil aviation careers.
Dust-enshrouded AGNs Can Dominate Host-galaxy-scale Cold Dust Emission
Authors: McKinney Jed , Hayward Christopher C. , Rosenthal Lee J. , Martínez-Galarza Juan Rafael , Pope Alexandra , Sajina Anna , Smith Howard A.
Published: October 2021

It is widely assumed that long-wavelength infrared (IR) emission from cold dust (T ∼ 20–40 K) is a reliable tracer of star formation even in the presence of a bright active galactic nucleus (AGN). Based on radiative transfer (RT) models of clumpy AGN tori, hot dust emission from the torus contributes negligibly to the galaxy spectral energy distribution (SED) at λ ≳ 100 μm. However, these models do not include AGN heating of host-galaxy-scale diffuse dust, which may have far-IR (FIR) colors comparable to cold diffuse dust heated by stars. To quantify the contribution of AGN heating to host-galaxy-scale cold dust emission at λ ≳ 100 μm, we perform dust RT calculations on a simulated galaxy merger both including and excluding the bright AGN that it hosts. By differencing the SEDs yielded by RT calculations with and without AGNs that are otherwise identical, we quantify the FIR cold dust emission arising solely from reprocessed AGN photons. In extreme cases, AGN-heated host-galaxy-scale dust can increase galaxy-integrated FIR flux densities by factors of 2–4; star formation rates calculated from the FIR luminosity assuming no AGN contribution can overestimate the true value by comparable factors. Because the FIR colors of such systems are similar to those of purely star-forming galaxies and redder than torus models, broadband SED decomposition may be insufficient for disentangling the contributions of stars and heavily dust-enshrouded AGNs in the most IR-luminous galaxies. We demonstrate how kiloparsec-scale resolved observations can be used to identify deeply dust-enshrouded AGNs with cool FIR colors when spectroscopic and/or X-ray detection methods are unavailable.
The IGRINS YSO Survey. I. Stellar Parameters of Pre-main-sequence Stars in Taurus-Auriga
Authors: López-Valdivia Ricardo , Sokal Kimberly R. , Mace Gregory N. , Kidder Benjamin T. , Hussaini Maryam , Nofi Larissa , Prato L. , Johns-Krull Christopher M. , Oh Heeyoung , Lee Jae-Joon , Park Chan , Oh Jae Sok , Kraus Adam , Kaplan Kyle F. , Llama Joe , Mann Andrew W. , Kim Hwihyun , Gully-Santiago Michael A. , Lee Hye-In , Pak Soojong , Hwang Narae , Jaffe Daniel T.
Published: October 2021

We present fundamental parameters for 110 canonical K- and M-type (1.3−0.13 M
⊙) Taurus-Auriga young stellar objects (YSOs). The analysis produces a simultaneous determination of effective temperature (T
eff), surface gravity (log g), magnetic-field strength (B), and projected rotational velocity (

v
sin
i

). Our method employed synthetic spectra and high-resolution (R ∼ 45,000) near-infrared spectra taken with the Immersion GRating INfrared Spectrometer (IGRINS) to fit specific K-band spectral regions most sensitive to those parameters. The use of these high-resolution spectra reduces the influence of distance uncertainties, reddening, and non-photospheric continuum emission on the parameter determinations. The median total (fit + systematic) uncertainties were 170 K, 0.28 dex, 0.60 kG, 2.5 km s−1 for T
eff, log g, B, and

v
sin
i

, respectively. We determined B for 41 Taurus YSOs (upper limits for the remainder) and find systematic offsets (lower T
eff, higher log g and

v
sin
i

) in parameters when B is measurable but not considered in the fit. The average log g for the Class ii and Class iii objects differs by 0.23 ± 0.05 dex, which is consistent with Class iii objects being the more evolved members of the star-forming region. However, the dispersion in log g is greater than the uncertainties, which highlights how the YSO classification correlates with age (log g), yet there are exceptionally young (lower log g) Class iii YSOs and relatively old (higher log g) Class ii YSOs with unexplained evolutionary histories. The spectra from this work are provided in an online repository along with TW Hydrae Association comparison objects and the model grid used in our analysis.
A Wide and Deep Exploration of Radio Galaxies with Subaru HSC (WERGS). IV. Rapidly Growing (Super)Massive Black Holes in Extremely Radio-loud Galaxies
Authors: Ichikawa Kohei , Yamashita Takuji , Toba Yoshiki , Nagao Tohru , Inayoshi Kohei , Charisi Maria , He Wanqiu , Wagner Alexander Y. , Akiyama Masayuki , Vijarnwannaluk Bovornpratch , Chen Xiaoyang , Kajisawa Masaru , Kawamuro Taiki , Lee Chien-Hsiu , Matsuoka Yoshiki , Schramm Malte , Suh Hyewon , Tanaka Masayuki , Uchiyama Hisakazu , Ueda Yoshihiro , Pflugradt Janek , Fukuchi Hikaru
Published: October 2021

We present the optical and infrared properties of 39 extremely radio-loud galaxies discovered by cross-matching the Subaru/Hyper Suprime-Cam (HSC) deep optical imaging survey and VLA/FIRST 1.4 GHz radio survey. The recent Subaru/HSC strategic survey revealed optically faint radio galaxies (RG) down to g
AB ∼ 26, opening a new parameter space of extremely radio-loud galaxies (ERGs) with radio-loudness parameter of

log



rest

=
log
(

f

1.4
GHz
,
rest

/

f

g
,
rest

)
>
4

. Because of their optical faintness and small number density of ∼1 deg−2, such ERGs were difficult to find in the previous wide but shallow or deep but small area optical surveys. ERGs show intriguing properties that are different from the conventional RGs: (1) most ERGs reside above or on the star-forming main-sequence and some of them might be low-mass galaxies with

log
(

M

⋆

/

M

⊙

)
<
10

. (2) ERGs exhibit a high specific black hole accretion rate, reaching the order of the Eddington limit. The intrinsic radio loudness (



int

), defined by the ratio of jet power over bolometric radiation luminosity, is one order of magnitude higher than that of radio quasars. This suggests that ERGs harbor a unique type of active galactic nuclei (AGN) that show both powerful radiations and jets. Therefore, ERGs are prominent candidates of very rapidly growing black holes reaching Eddington-limited accretion just before the onset of intensive AGN feedback.
A Core Mass Function Indistinguishable from the Salpeter Stellar Initial Mass Function Using 1000 au Resolution ALMA Observations
Authors: Suárez Genaro , Galván-Madrid Roberto , Aguilar Luis , Ginsburg Adam , Srinivasan Sundar , Liu Hauyu Baobab , Román-Zúñiga Carlos G.
Published: October 2021

We present the core mass function (CMF) of the massive star-forming clump G33.92 + 0.11 using 1.3 mm observations obtained with the Atacama Large Millimeter/submillimeter Array (ALMA). With a resolution of 1000 au, this is one of the highest resolution CMF measurements to date. The CMF is corrected by flux and number incompleteness to obtain a sample that is complete for gas masses M ≳ 2.0 M
⊙. The resulting CMF is well represented by a power-law function (

dN

/

d
log
M
∝

M

Γ

), whose slope is determined using two different approaches: (i) by least-squares fitting of power-law functions to the flux- and number-corrected CMF, and (ii) by comparing the observed CMF to simulated samples with similar incompleteness. We provide a prescription to quantify and correct a flattening bias affecting the slope fits in the first approach, which is caused by small-sample or edge effects when the data are represented by either classical histograms or a kernel density estimate, respectively. The resulting slopes from both approaches are in good agreement each other, with

Γ
=
−

1.11

−
0.11

+
0.12

being our adopted value. Although this slope appears to be slightly flatter than the Salpeter slope Γ = −1.35 for the stellar initial mass function (IMF), we find from Monte Carlo simulations that the CMF in G33.92 + 0.11 is statistically indistinguishable from the Salpeter representation of the stellar IMF. Our results are consistent with the idea that the form of the IMF is inherited from the CMF, at least at high masses and when the latter is observed at high enough resolution.
Genetic heterogeneity of beta thalassemia mutations in Kahramanmaraş province in Southern Turkey: preliminary report
Authors: Kurutaş Ergul Belge , Aksan Mehmet Emrah , Curuk Petek , Curuk Mehmet Akif
Published: October 2021

Background: Beta thalassemia is one of the most common autosomal single-gene disorders in the world. The prevalence of the disease is in the “thalassemia belt” which includes the Mediterranean region of Turkey; throughout the country the gene frequency is estimated to be 2.1%, but in certain regions, this figure increases to 10%.

Aim: In this first study, we aimed to determine the frequency of β-thalassemia trait and distrubition of mutations in Kahramanmaraş province, which is located in the southern part of Turkey.

Materials and Methods: In this study; 5 ml blood samples was taken from 14 thalassemic patients and their relatives who were taking care of Sutcu Imam University Hospital at Kahramanmaraş. Also, we collected blood samples from 245 adults for screening beta thalassemia trait. Haematological data were obtained by cell counter.  HbA2 was determined by HPLC. Ten common mutations were screened by ARMS  (Amplification Refractory Mutation System) method. These β-thalassemia mutations are -30 (T>A), Fsc8 (-AA), Fsc8/9 (+G), IVS1-1 (G>A), IVS1-5 (G>C), IVS1-6 (T>C), IVS1-110 (G>A ), Cd 39 ( C>T), IVS2-1 (G>A), IVS 2-745 (C>G). A rare mutation; Fsc44 (-C) was charecterized by DNA sequencing.

Results: Ten patients were detected as homozygous for IVS1-110 (seven cases), Fsc 44 (two cases) and IVS1-5 (only one case). Rest of the 4 patients were double heterozygous (two: IVS1-110/IVS1-6, one: Fsc8/Fsc8-9, one: IVS2-1/IVS1-5). In 245 adult, five  β-thalassemia trait were detected by screening survey. 

Conclusion: Sixteen alleles were detected as IVS1-110 in 57.1%. It was seen the most common mutation in Kahramanmaraş. Seven different β-thalassemia mutations were found in this study. Each of 10 families have only one thalassemic patient, other two families have double thalassemic patient in total 12 family.
Familial hyperinsulinaemic hypoglycaemia with epileptic syndrome, cognitive impairment and detected mutation of the ABCC 8 (SUR1) gene: a case report
Authors: Shopova Ana , Shopova Silvia , Stefanova Irina , Kuzmanova Rumyana
Published: October 2021

Hyperinsulinaemic hypoglycaemia (HH) occurs as a consequence of unregulated insulin secretion from pancreatic beta cells. It is the most common cause of severe and prolonged hypoglycemia in newborns. HH is a major risk factor for brain damage and subsequent neurological disability, which is why the identification, rapid diagnosis, and timely treatment of patients with HH are essential for the prevention of brain damage. The present case gives a brief description of a patient with congenital HH with an established mutation in the ABCC8 gene encoding the SUR1 subunit of the K-ATP channel. The genealogical tree, the clinical picture, the diagnostic cascade, the neurological consequences and their development in dynamics are considered, with special emphasis on the epileptic syndrome and mental status. Advances in molecular genetics, radiological imaging techniques, conservative treatment, or laparoscopic surgery may completely change the clinical approach to children with severe congenital forms of HH.
Does dihydropyrimidine dehydrogenase level modify plasma antioxidant capacity in colorectal cancer patients treated with fluoropyrimidines? 
Authors: Minchev Velko , Hristova-Avakumova Nadya , Kamenova Kalina , Atanasova Liliya , Angelov Marin , Todorov Lozan , Surcheva Slavina , Nikolov Rumen
Published: October 2021

Introduction: Colorectal cancer is the third most common cancer type worldwide. Fluoropyrimidines and their prodrug-based regimens are widely applied as primary medications. The main enzyme responsible for the rate-limiting step in pyrimidine and for the 5-fluorouracil catabolism is dihydropyrimidine dehydrogenase (DPD).

Aim: We aimed to screen DPD level and the changes of plasma antioxidant capacity of colorectal cancer patients on 5-fluorouracil regimen. 

Materials and methods: Human DPD Elisa Kit based on sandwich enzyme-linked immune-sorbent assay and spectrophotometric methods (FRAP and ABTS) were used in the study.

Results: No statistically significant changes in plasma scavenging activity according to the results obtained in the ABTS system have been observed after evaluating all patients and considering DPD concentration. A decrease of the ferric reducing ability of patients’ plasma taken after the administered treatment was found. The increase of DPD level is accompanied by a decrease in the p values and therefore the statistical significance of the differences increases.

Conclusions: Based on the aforementioned observations, it could be concluded that some aspects of plasma antioxidant capacity and individuals’ antioxidant status might be involved in the pathogenesis of the disease and could be altered by the activity of some enzymes. The cancer therapy in question, by the specificity of its mechanism of action, can modify patient’s oxidative status.
Evaluation of some trace elements in sera of asthma patients: a case control study.
Authors: Al-Fartusie Falah S. , Abood Manal J. , Al-Bairmani Hassanain K. , Mohammed Ahmed S.
Published: October 2021

Introduction: Asthma is a chronic inﬂammatory disease of the airways characterized by recurrent respiratory symptoms of dyspnea, wheezing, chest tightness, and cough.

Aim: This study aims to investigate the concentrations of Cu, Zn, Mg, Mn, Fe, Cr, Ni, and Al in the serum of asthmatic patients.

Materials and methods: An atomic absorption technique was used to determine the levels of trace elements. The study included sixty asthmatic patients and ninety healthy individuals as control group their ages ranging from 20 to 45 years.

Results: We found a significant increase of the levels of copper, iron, and aluminum by 20%, 54%, and 47% (p<0.01), respectively, in the asthmatic patients as compared with the controls. On the other hand, in comparison with the controls, the levels of zinc, magnesium, manganese, and nickel were found to be significantly decreased (p<0.01) by 24%, 16%, 53%, and 81%, respectively, in the asthmatic patient group. Moreover, chromium level showed non-significant differences (p>0.05) between patients and control group.

Conclusions: The increased level of Cu and Fe may reflect their potential role in the pathogenesis of asthma. Furthermore, the serum iron levels tend to be increased as a result of the inflammatory process that occurs in asthma. Low levels of Zn, Mg, and Mn may contribute to allergic diseases due to their role in the synthesis of certain antioxidants or to their effect on the immune system.
Twelve new species of Dipara Walker, 1833 (Hymenoptera, Chalcidoidea, Pteromalidae, Diparinae) from Kenya, with a key to the Afrotropical species
Authors: Braun Christoph , Peters Ralph S.
Published: October 2021

Based on 261 female specimens of the genus Dipara Walker, 1833 from leaf litter samples of the Kakamega Forest in Kenya, we describe the following twelve new species: Dipara andreabalzeraesp. nov., Dipara coronasp. nov., Dipara fastigatasp. nov., Dipara kakamegensissp. nov., Dipara luxsp. nov., Dipara nigroscutellatasp. nov., Dipara nyanisp. nov., Dipara reticulatasp. nov., Dipara rodneymullenisp. nov., Dipara sapphirussp. nov., Dipara tenebrasp. nov., and Dipara tigrinasp. nov. For Dipara albomaculata (Hedqvist, 1963) and Dipara nigrita Hedqvist, 1969, we give new distribution records. We examined the available type material of all described Dipara species from the Afrotropical mainland, i.e., Dipara albomaculata (Hedqvist, 1963), Dipara machadoi (Hedqvist, 1971), Dipara maculata (Hedqvist, 1963), Dipara nigrita Hedqvist, 1969, Dipara pallida (Hedqvist, 1969), Dipara punctulata (Hedqvist, 1969), Dipara saetosa (Delucchi, 1962), Dipara straminea (Hedqvist, 1969), Dipara striata (Hedqvist, 1969), and Dipara turneri Hedqvist, 1969. We provide figures, descriptions, and diagnoses of the newly described species and figures and diagnoses of the ten known species as well as an identification key to all species of the Afrotropical mainland.
Le rôle des revues en France avant et après la Seconde Guerre mondiale
Authors: Dosse François
Published: October 2021

Les revues constituent le poumon de la vie intellectuelle. Ce sont dans ces réseaux de sociabilité qu’émerge l’essentiel des idées constitutives de la koïné d’un moment historique. Par ce panorama, nous avons voulu reconstituer le paysage dans lequel Paul Ricœur a évolué entre l’avant-guerre et les années 1990.
À travers ses archives, l’inlassable effort de l’homme engagé
Authors: Goldenstein Catherine
Published: October 2021

À travers ses archives, l’inlassable effort de l’homme engagé Paul Ricœur a marqué son temps par son enseignement, son œuvre impressionnante, mais aussi pour avoir agi, vécu et porté autrui à agir et à vivre. Outre les nombreuses publications, les « archives personnelles », nombreux documents de travail du Fonds Ricœur, permettent de confirmer ce que sa biographie révèle : une grande constance dans cette vie d’enseignement, de conviction, d’engagements entrelacés. Ses engagements les plus marquants et durables l’ont été dans des communautés intellectuelles réunies autour de revues. Quelles traces de ces entreprises collectives reste-t-il dans les archives, et que peut-on y déceler qui ne soit connu par les textes ? Après avoir dressé les gros blocs des revues auxquelles Ricœur a été le plus fidèle, mon propos est de faire ressortir à travers les archives quelques traits, quelques façons de faire sur le vif.
Présence des Apaches
Authors: Albera François
Published: October 2021

À une période où nombre de revues disparaissent et notamment les revues de cinéma – dont l’audience a fortement décru depuis quelques décennies –, la naissance d’un nouveau titre fait événement. La revue Apaches dans son premier numéro se place sous l’égide d’un auteur de film, Fritz Lang, et d’un courant critique des années 1950-1960, le mac-mahonisme qui l’avait érigé avec un nombre restreint d’autres cinéastes (Losey, Preminger, Walsh, Cottafavi, Freda) en modèles. Quel lien peuvent avoir de jeunes critiques, soucieux de se « faire une place », avec une démarche très inscrite dans une histoire des cinéphilies de l’après-Deuxième Guerre mondiale en France tant aux plans des choix esthétiques qu’idéologiques. C’est l’occasion d’évoquer Présence du cinéma qui servit de « tribune » aux mac-mahoniens, et le contexte dans lequel elle voit le jour. La définition de la fonction critique, du positionnement de la critique est alors au centre des réflexions de ses protagonistes. Le numéro 126 des Cahiers du cinéma (décembre 1961) se consacrait entièrement à la question avec table ronde, textes programmatiques et enquêtes auprès de dizaines de critiques – à l’exception des animateurs de Présence du cinéma . Refusèrent-ils l’exercice ou en furent-ils écartés ?
Le secrétariat de l’épiscopat et la naissance de la Sécurité sociale (1945-1950)
Authors: Moisset Jean-Pierre
Published: October 2021

L’établissement de la Sécurité sociale en France en 1945 place les évêques ainsi que les supérieures et supérieurs de congrégations devant l’hypothèse de l’assujettissement des prêtres ainsi que des religieuses et des religieux. Or, les autorités catholiques jugent la nouvelle institution publique inadaptée à l’Église catholique. En outre, elles perçoivent la Sécurité sociale comme un système bureaucratique sous influence communiste. Aussi, se lancent-elles dans un long combat judiciaire et politique contre un assujettissement qui leur paraît à la fois onéreux et dangereux. Adoptée le 19 février 1950, la loi Viatte en est le principal résultat. En effet, elle exempte du rattachement à un régime de sécurité sociale les ministres du culte catholique dont l’activité est « exclusivement religieuse ».
L’assurance maladie à l’assaut de l’hôpital public ? Des administrations en lutte pour le contrôle de la réforme hospitalière
Authors: Gay Renaud
Published: October 2021

Le système hospitalier est transformé, depuis les années 1960, par une succession de réformes dont la construction s’inscrit dans des luttes renouvelées entre les acteurs de l’assurance maladie et de l’administration sanitaire qui donnent à voir des oppositions de savoir-faire et de représentations. La dynamique et l’issue de ces luttes nous renseignent sur les capacités d’action des organisations de l’assurance maladie sur le système hospitalier. Trois séquences historiques sont distinguées sur la base des formes d’intervention de ces organisations sur la fabrication des réformes et des effets de ces dernières sur leurs domaines et capacités d’action.
Interplay of random inputs and adaptive couplings in the Winfree model
Authors: Ha Seung-Yeal , Kim Doheon , Moon Bora
Published: October 2021

We study a structural robustness of the complete oscillator death state in the Winfree model with random inputs and adaptive couplings. For this, we present a sufficient framework formulated in terms of initial data, natural frequencies and adaptive coupling strengths. In our proposed framework, we derive propagation of infinitesimal variations in random space and asymptotic disappearance of random effects which exhibits the robustness of the complete oscillator death state for the random Winfree model.