bluuebunny/crossref_metadata_2025 huggingface dataset:
Deformasi Permanen Terhadap Penggunaan Lateks sebagai Bahan Tambah pada Campuran Beton Aspal
Authors: Massara Asma , Jannah Miftahul , AS Putri Catryna
Published: July 2023

Sebagai penunjang dalam kelancaran transportasi, jalan memiliki peranan yang sangat penting sehingga diperlukan kondisi perkerasan yang bagus agar menjadi aman, lancar dan nyaman dalam berlalu lintas. Pembebanan yang terjadi dalam perkerasan terbagi dua, yaitu pembebanan tarik dan tekan. Penelitian ini dikakukan dengan tujuan untuk menganalisis kadar aspal optimum untuk pencampuran Lateks/getah pohon sebagai bahan tambah serta untuk mengetahui pengaruh campuran Lateks terhadap Deformasi Permanen. Kadar aspal rencana yang digunakan yaitu 5,0%, 5,5%, 6,0%, 6,5%, dan 7,0%. Pengujian awal dengan alat Marshall Test untuk mendapatkan kadar aspal optimum (KAO). Pengujian selanjutnya dengan menggunakan alat Wheel Tracking Test. KAO yang digunakan yaitu 6,0% dan kadar Lateks yaitu 0,0%, 2%, 4%, 6%, dan 8%. Dari hasil pengujian Wheel Tracking Test, pada suhu 30oC komposisi dengan variasi kadar lateks 2% menunjukkan tingkat ketahanan deformasi paling rendah, dengan total deformasi 0,70 mm. Berdasarkan hasil tersebut variasi kadar lateks 2% memberikan hasil lebih baik dari pada kadar lateks yang lain.
Studi Sarana Perparkiran Dalam Rencana Pengelolahan Nipah Mall Kota Makassar
Authors: Gani Ishak , Nurhikma  , Halisyah Nur
Published: July 2023

Studi mengenai ruang karakteristik dan kebutuhan parkir pada pusat perbelanjaan sangat perlu dilakukan. Kurangnya fasilitas parkir di kawasan tertentu dalam kota, menyebabkan badan jalan menjadi tempat parkir (on street parking).Tujuan penelitian ini untuk mengetahui karakteristik dan kebutuhan lahan parkir serta situasi/kondisi parkir di Nipah Mall Kota Makassar. Pada penelitian ini mengambil sampel data berupa peta lokasi,denah ruang parkir, luas lahan, luas area parkir, kuisioner, jumlah petak parkir serta kondisi/situasi lokasi parkir melalui survey di Nipah Mall Kota Makassar. Metode yang digunakan meliputi analisa inventarisasi fasilitas parkir berdasarkan luas lantai bangunan, analisa kebutuhan ruang dan lahan parkir Menurut Standarisasi SRP Pusat Perdagangan, serta analisa data responden berdasarkan rumus slovin. Hasil analisa membuktikan bahwa jumlah SRP yang tersedia di lokasi tidak sesuai berdasakan luas lantai bangunan parkir serta permintaan ruang parkir lebih besar atau melebihi kapasitas yang ada. Selain itu, kebutuhan lahan parkir lebih besar dibandingkan lahan parkir eksisting. Maka dari itu perlu adanya penataan penggunaan waktu parkir setiap kendaraan serta penambahan ruang parkir dengan mencari lahan parkir lain untuk memenuhi kebutuhan parkir.
Studi Ketersediaan Ruang Terbuka Hijau Publik di Kota Watampone
Authors: Siti Fatmah Arsal  , Indra Pratama  , Sainal
Published: July 2023

Masalah perkotaan pada saat ini telah menjadi masalah yang cukup susah untuk diatasi. Perkembangan perkotaan membawa pada konsekuensi negatif pada beberapa aspek, termasuk aspek lingkungan. Dalam tahap awal perkembangan kota, sebagian besar lahan merupakan ruang terbuka hijau. Namun, adanya kebutuhan ruang untuk menampung penduduk dan aktivitasnya, Strategi pemanfaatan ruang, baik untuk kawasan budidaya maupun kawasan lindung, perlu dilakukan secara kreatif, sehingga konversi lahan dari pertanian produktif ataupun dari kawasan hijau lainnya menjadikawasan non hijau dan non produktif, dapat dikendalikan. Bagi kota besar, cara mengatasi banjir juga bisa dilakukan dengan memperluas ruang terbuka hijau. Padahal sebenarnya bagi sebuah kota, terutama kota besar yang termasuk kedalam daerah rawan banjir, perlu dibangun berupa lahan hijau sebesar 30% dari luas kota itu. Bagi kota besar, cara mengatasi banjir juga bisa dilakukan dengan memperluas ruang terbuka hijau. Padahal bagi sebuah kota, terutama kota besar yang daerah rawan banjir, perlu dibangun berupa lahan hijau sebesar 30% dari luas kota itu. Dari hasil penelitian dapat ditarik kesimpulan bahwa pada kota watampone ada 2 kecamatan yang belum memenuhi persentase ruang terbuka hijau yaitu Kecamatan Tanateriattang Barat sebesar 16% dan pada kecamatan tanateriattang sebesar 28% dari ketentuan UU no. 26 tahun 2007 minimal rth sebesar 30%dari luas wilayah.
Kajian Perbedaan Campuran Beraspal Panas Yang Menggunakan Bahan Agregat Dengan Berat Jenis (Specfic Grafity) yang Berbeda
Authors: Adwang Jimmy
Published: July 2023

Berat jenis aggregat merupakan rasio berat per volume agregat di udara dengan di air. Berat jenis mempengaruhi parameter pengujian Marshall yaitu Stabilitas, Flow, VIM, VMA, VFB, dan kepadatan. Penelitian ini bertujuan untuk mengkaji perbedaan campuran beraspal panas yang menggunakan bahan agregat dengan berat jenis berbeda. Benda uji terdiri dari material batu pecah yang bersumber dari tiga tempat yaitu Kakaskasen Kota Tomohon, Tateli Kabupaten Minahasa dan Matali Kota Kotamobagu, dengan aspal penetrasi 60/70 ex Pertamina. Berikut adalah hasil pengujian Marshall setiap material pada kadar aspal 6,5%. Material Matali dengan berat jenis tinggi (2.7) nilai stabilitasnya 2045 kg; flow 2.70 mm; VIM 3.53%; VMA 17.67%; VFB 80.10%; dan density 2.40 gr/cc; Material Tateli dengan berat jenis antara 2.4 dan 2.3 stabilitas sebesar 1450 kg; flow 3.01mm; VIM 3.67%; VMA 15.43%; VFB 76.24%; density 2.18 gr/cc. Material Kakaskasen dengan berat jenis pada interval 2.4 dan 2.3 stabilitas sebesar 1535 kg, flow 3.49mm; VIM 4.58%; VMA 15.10%; VFB 69.71%, density 2.15 gr/cc. Semakin tinggi nilai berat jenis material, semakin tinggi pula nilai density. Jika satuan pembayaran campuran beraspal panas dalam satuan berat, maka menggunakan agregat dengan berat jenis lebih besar relatif lebih mengguntungkan sehingga disarankan penggunaan material dengan berat jenis tinggi dalam pekerjaan jalan.
LINGUISTIC DEVIATIONS IN THE PRACTICE OF OFFICIAL RECORDING OF THE PERSONAL NAMES OF POLISH COMMUNITY MEMBERS IN UKRAINE IN THE EARLY 21ST CENTURY
Authors:   O. O. Potebnia Institute of Linguistics of the NAS of Ukraine, HOLOTOVA Iryna
Published: July 2023

The article is devoted to the analysis of the personal names of representatives of the Polish community of Khmelnytskyi from the point of view of their compliance with the norms of the contemporary Ukrainian literary language. The article considers the main types of linguistic deviations in the personal names records of the representatives of the Polish community of Ukraine at the beginning of the 21st century from the sociolinguistic perspective. Linguistic deviations in contemporary Ukrainian anthroponymy are caused by several reasons, the main of which are Ukrainian-Russian bilingualism, the dominance in the communicative practice of variants of names borrowed from the Russian language, as well as a significant number of borrowed names that do not have an established tradition of reproduction in the Ukrainian language. The connection between the language situation and the occurrence of language deviations in the records of personal names is traced using the example of the Polish community of Khmelnytskyi. The language situation in the Polish community of Khmelnytskyi can be characterized as Ukrainian-Russian-Polish trilingualism. Practices of alternating use of the Ukrainian, Russian, and Polish languages cause the emergence of deviant variants of personal names under the influence of the phonetic standards of the Russian and Polish languages. The correct spelling of the name is influenced by the awareness of the spelling of the Ukrainian language, literacy, language skills, and the nationality of the priest. Catholic priests, who often belong to the Polish nationality, carry out documentation of the personal names from the verbal message of the parents, using the Russian language, which leads to the entry of deviant forms of personal names into official documents. The variability of personal names is determined by the peculiarities of the stylistic use of anthroponyms, colloquial speech, dialectal speech, and regional specificity. A quantitative correlation of normative and deviant variants in records of personal names was determined. The tendencies of the creation of the contemporary naming system of the ethnic minorities of Ukraine under the influence of Ukrainian- Russian bilingualism are analyzed.
Development of copper nanoparticles and their prospective uses as antioxidants, antimicrobials, anticancer agents in the pharmaceutical sector
Authors: Tyagi Pankaj K. , Arya Arvind , Mazumder Avijit Mazumder , Tyagi Shruti
Published: July 2023

In this study, we review the synthesis of copper nanoparticles (CuNPs) and their prospective uses as antioxidants, antimicrobials, and anticancer agents in the pharmaceutical sector. Copper nanoparticles could be created through a variety of methods, including chemical reduction, green synthesis, physical methods, electrochemical deposition, and the microemulsion method. These methods make it possible to precisely create nanoparticles with the necessary shapes, sizes, and surface properties, which in turn affect how well they perform biologically. CuNPs have strong antioxidant properties because they can scavenge reactive oxygen species (ROS) and prevent oxidative damage. In addition to their antioxidant properties, CuNPs show antibacterial activity against a number of microbes, including bacteria, fungi, and viruses. The potential of CuNPs as an anticancer agent has also been extensively investigated. These nanoparticles have toxic effects on a variety of cancer cell lines by inducing apoptosis, inhibiting cell proliferation, and preventing tumour angiogenesis. Because of their specific toxicity towards cancer cells while protecting normal cells, they provide the fascinating potential for tailored therapy to overcome multidrug resistance. CuNPs have also been studied in relation to their usage in medications. They may be utilised to improve drug delivery systems, wound healing, diagnostic imaging, immunotherapy, and anti-inflammatory and antioxidant effects. They can also be used to improve pharmaceutical stability, bioavailability, and provide controlled release. More research is needed to ensure their safety, enhance their synthesis processes, and explore their full potential in therapeutic situations
Effectiveness of D-Mat on Improving Basic Jumping Motions in Early Children in Palembang
Authors: Dewi Septaliza  , Sukmawati Noviria , Selvi Melianty  , Selvi Atesya Kesumawati
Published: July 2023

Mastery of basic movements must start from an early age, because mastering basic movement abilities is an important foundation for children to be able to be involved in many kinds of physical activities in the future. This research is related to the basic motion of jumping. The aim of this study was to determine the effectiveness of D-Mat in increasing basic jumping motion in early childhood. This type of research is experimental research by providing treatment in the form of a game method with D- Mat in early childhood. The sample used in this study is the total number of early childhood children in early childhood education. The data were obtained from the results of the pretest and posttest. The research sample consisted of 4-5 years old children in TK Negeri Pembina 4 and TK Kurnia Makmur Palembang totaling 30 people. Data analysis techniques using the t test. Based on the results of the research based on the t-test calculation, the value of fcount <ftable or 4.29 <1.693 means that Ho is rejected and Ha is accepted. This shows that the child's final ability is better than before using the D-Mat. It can be concluded that D-Mat is effectively used to improve basic jumping motion in early childhood in Palembang. It is suggested that the D-Mat mat can be used in physical activities as well as learning because the D-Mat contains pictures of letters and numbers.
Rancang Bangun Sistem Informasi E-Learning Berbasis Website untuk Program Kejar Paket C di PKBM Bina Bangsa Sumbersuko
Authors: Cahyati Tri Nur , Rahmawati Zurriat Nyndia , Wahyudi Farid , Fahmi Muhammad Hanif , Tasaufi Bila Nastiti
Published: July 2023

Kualitas Pembelajaran yang tidak sesuai dengan pembelajaran formal serta pembelajaran yang sangat singkat membuat peserta didik harus mempelajari materi tambahan dengan referensi pembelajaran yang tidak terhimpun sesuai kurikulum yang diajarkan membuat hal-hal tersebut menghambat jalannya pembelajaran. Penelitian ini bertujuan untuk mengembangkan e-learning berbasis website di PKBM Bina Bangsa Sumbersuko. E-learning didesain untuk digunakan pada program kejar paket C atau setara SLTA. Website e-learning ini mengakomodir beberapa pengguna sistem yaitu admin, tutor, dan siswa. Website dirancang dengan menggunakan server local (localhost), bahasa pemrograman PHP, basis data MySQL, dan menggunakan Bootstrap Framework. Alur pembuatan sistem dilakukan menggunakan model Waterfall dengan pengujian sistem menggunakan metode black box. Secara keseluruhan e-learning berjalan dengan baik dan dengan  hasil pengujian sistem berjalan dengan baik, serta sistem dapat diimplementasikan pada program Kejar Paket C serta sebagai sarana penyampaian informasi yang terpusat di PKBM Bina Bangsa Sumbersuko.
Development of a Mobile-Based Commodity Exchange Information Application Prototype for Indonesian Companies
Authors: Gaghana Krizia Gidion , Sutomo Rudi
Published: July 2023

Commodity exchanges are marketplaces where various commodities, including metals, energy, agriculture, etc., are traded. Here, buyers, sellers, and investors can transact in spot contracts or items futures. According to literature reviews based on prior research, in-person contacts and encounters can strengthen professional ties, create a sense of trust, and provide a thorough understanding of client preferences and wants. Online commodity dealing may have this restriction because there may be little opportunity for in-person encounters. Mobile electronic communication technologies and media can diminish face-to-face human interaction while facilitating information access and sharing to solve this issue. A computer, laptop, or mobile device can be used to access this platform, which is an online trading system. Traders can view current commodity pricing information. A mobile-based application for Commodity Exchange Information that was created using Flutter technologies and the Extreme Programming approach is one of the most successful and effective methods of information dissemination. With powerful indicators and user needs, the User Acceptance Test (UAT) method and the Black-box testing model's final step of application testing yielded a score of 93.75%.
A Basilar Artery Dissection Mimicking Acute Labyrinthitis in A 15-Year-Old Girl
Authors: Yoon So Yeon , Cho Youn Jin , Kim Minbum
Published: July 2023

Basilar artery dissection (BAD) is a rare cause of vertigo in children. A 15-year-old girl presented with sudden vertigo and unilateral hearing loss. Magnetic resonance imaging revealed posterior circulation infarction caused by BAD. After antiplatelet therapy, intratympanic injections of dexamethasone and vestibular rehabilitation, her symptoms improved. We report this case of BAD, which might be mistaken for acute peripheral vestibular disorders in the early stage.
The Clinical Manifestation and Temporal Bone Computed Tomography Findings of Non-Traumatic Hearing Loss With Air-Bone Gap and Intact Tympanic Membrane
Authors: Jeon Seung Yeon , An Yong-Hwi , Yoon Ra Gyoung , Shim Hyun Joon
Published: July 2023

Background and Objectives This study aimed to investigate the causes, clinical manifestations, temporal bone CT findings, and audiologic results of outpatients with non-traumatic hearing loss with air-bone gaps and intact tympanic membranes.Subjects and Method The medical records from 2014 to 2022 of 66 patients (77 ears) with normal tympanic membranes but who had the air-bone gap of more than 20 dB over two consecutive frequencies were reviewed.Results The mean age of the patients was 46.8±17.0 years old. The mean air-bone gap was 24.8±10.3 dB. Of the 77 ears (66 patients) studied, 10 ears were surgically diagnosed with otosclerosis (6 ears), ossicular discontinuity (2 ears), superior semicircular canal dehiscence (1 ear), and unknown etiology (1 ear). Additionally, 29 more ears (28 patients) were clinically diagnosed with silent otitis media (7 ears), otosclerosis (5 ears), thickened tympanic membrane (5 eras), E-tube dysfunction (4 ears), ossicular anomaly (4 ears), semicircular canal dysplasia (2 ears), and endolymphatic hydrops (2 ears). Temporal bone CT images showed normal findings in 33 ears (54.1%) and abnormal findings in 28 ears (45.9%). Patients with abnormal CT findings had a poorer speech discrimination score than those with normal findings (p<0.05). The airbone gap was significantly decreased postoperatively from 30.5±12.7 dB to 6.4±4.0 dB, with a tendency to decrease greater at a low frequency than at a high frequency.Conclusion Among patients with air-bone gap and intact tympanic membrane, otosclerosis was the most commonly confirmed diagnosis through surgery, while silent otitis media was the most frequently observed diagnosis based on clinical evaluations.
A Case of Bilateral Plunging Ranula
Authors: Hong Seong-Eun , Kim Brian , Lee Myung-Chul , Choi Ik Joon
Published: July 2023

A plunging ranula is a pseudocyst in the neck that originates from the sublingual gland in the process of mucus extravasation and herniation. It has been widely suggested that the cause of a plunging ranula is due to a congenital predisposition involving the dehiscence of the mylohyoid muscle, racial predisposition and previous oral trauma. Even though unilateral plunging ranula is rare, and bilateral plunging ranulas are even more rare. We recently experienced a case of bilateral plunging ranula in a 27-year-old male. He presented with a right-sided submandibular swelling and was diagnosed with a plunging ranula and right ranula excision and sublingual gland excision was performed. He visited the outpatient department with contralateral submandibular swelling after 18 months of operation. Under the diagnosis of left plunging ranula, he underwent surgery in the same way as before. We suggest that all patients with a unilateral plunging ranula, although rare, should be considered for the possibility of developing contralateral diseases.
Genetic Analysis of Locally Advanced Well-Differentiated Thyroid Cancer: Clinical Prognostic Implications
Authors: Jung Ah Ra , Kang Sun Seong , Jeon Seung Yeon , Lee Yoon Se
Published: July 2023

Background and Objectives Despite the usually favorable prognosis of well-differentiated thyroid cancer (WDTC) following appropriate treatment, advanced T-staged WDTCs are associated with poor prognosis. This study focused on identifying genes associated with the prognosis of locally advanced WDTC by analyzing a The Cancer Genome Atlas cohort.Subjects and Method We analyzed the data of 501 patients with WDTC and classified them into two subgroups: pathological T4 stage (Cluster 1) or T1-3 stage (Cluster 2). We compared the mRNA expressions of thyroid cancer-related genes, and the somatic mutation frequencies of various cancer genes between the two subgroups.Results Cluster 1 included 23 patients (papillary=21/follicular-variant papillary thyroid cancer [FVPTC]=2) and Cluster 2 478 patients (papillary=371/FVPTC=100/others=7). Cluster 1 showed worse overall and disease-free survival than Cluster 2 (p<0.05 and p=0.12, respectively). Patients with pT4 stage had about a 1.8-fold increased risk of overall recurrence or death. MET, SERPINA1, TIMP1, PROS1, FN1, CDKN2A, and CDKN2B were significantly elevated while TG, DNAH9, TFF3, CRABP1, TPO, JAK2, KIT, KDR, and NFE2L2 were significantly lower in Cluster 1 (all, p<0.05 and adjusted p<0.05). A TERT, EIF1AX, and ATM showed significantly frequent somatic mutations in Cluster 1 when compared to Cluster 2. We also identified seven pathways related to 16 genetic markers.Conclusion Locally advanced WDTC presented 16 genetic alterations. We identified somatic mutations associated with local invasion transformation. Relevant pathways related to the 16 genetic markers could be therapeutic targets. Genetic analysis of locally advanced WDTC may be used to predict clinical applications in patient survival.
A Study on the Possibility of Neurological Morbidity of Prelacrimal Recess Approach Depending on Anatomical Differences
Authors: Koo Hyung-Bon , Son Sang-Jun , Lee Jae-Hoon
Published: July 2023

Background and Objectives The maxillary sinus disease is mainly treated through the middle meatal antrostomy, but there is a disadvantage in that it does not approach the lesions of the anterior wall of the maxillary sinus. On the other hand, the prelacrimal recess approach (PLA) can be used to access the lesions of the anterior wall of the maxillary sinus. However, complications after PLA may include nasal bleeding, infection, epiphora, and neurological symptoms. We investigated the possibility of neurological morbidity (anterior superior alveolar nerve injury) after PLA by imaging.Subjects and Method A total of 253 people were studied by using 506 samples of paranasal sinus CT. According to the Simmen and Arosio methods, the study groups were classified into the following categories: PLA type I (<3 mm), type II (3-7 mm), and type III (>7 mm), internal angle of pyriform notch (IAPN), type A (below 45°), type B (from 45° to 60°), and type C (60° excessive).Results Of the PLA types, the IAPN value was the largest in the type III and smallest in the type I, and there were significant differences among the three groups (p<0.001).Conclusion CT Evaluation prior to PLA would help physicians to predict the likelihood of neurological morbidity such as maxillary sensory abnormalities.
A Case of Parotid Gland Epithelial-Myoepithelial Carcinoma With Lung Metastasis: A Review of 26 Cases of Metastatic Epithelial-Myoepithelial Carcinoma
Authors: Kim Min Soo , Seo Ja Hee , Kwon Jun Yeob , Kim Seong Dong
Published: July 2023

Epithelial-myoepithelial carcinoma (EMCa) is rare, comprising 1% of all salivary gland tumors. Although it is a low-grade cancer, local recurrence occurs in 23%-50% of the cases. Distant metastasis with the rate of 2.6% is rare and there are only 26 cases that have been reported to date globally. The lung is the most predominant site of distant metastasis (17 cases), followed by the liver, bones, and the brain. We report here a case of a 68-year-old female diagnosed with EMCa of the parotid gland, initially managed via parotidectomy and postoperative radiotherapy. Metastasis in the lung was noted 38 months after radiotherapy, and was treated with four cycles of platinum-based chemotherapy. Minor regression of lung nodules was observed on computed tomography and was defined as a ‘stable disease.’ Since there is no reported case of EMCa with distant metastasis in Korea, we also reviewed 26 cases of metastatic EMCa globally reported.
Accuracy of the Information on Sudden Sensorineural Hearing Loss From Chat Generated Pre-Trained Transformer
Authors: Lee Sang Jae , Na Hyung Gyun , Choi Yoon Seok , Song Si-Youn , Kim Yong-Dae , Bae Chang Hoon
Published: July 2023

Background and Objectives Chat generated pre-trained transformer (ChatGPT) is a conversational artificial intelligence model, which has recently attracted worldwide attention by enabling natural conversations based on huge information from deep learing in various fields. Several studies have reported usefullness and reliability of medical information obtained by ChatGPT, but there are no studies explaining reliability and accuracy in the field of otorhinolarynoglogy. On this regard, we investigated the accuracy of information on sudden sensorineural hearing loss obtained by ChatGPT.Materials and Method Twenty-five questions and answeres related to sudden sensorineural hearing loss were recorded from ChatGPT based on textbook from Korean Society of Otorhinolaryngology-Head and Neck Surgery and Clinical Guidelines of American Academy of Otolaryngology-Head and Neck Surgery. Answers were shown to one specialist in otorhinolaryngoly in a blind test and asked to assess their accuracy. Each question was rated as ‘accurate’ or ‘inaccurate.’ If the contents were not found in the textbook or the guidelines, it was rated as ‘unreliable.’Results Of the 25 questions, 19 (76%) were identified as ‘accurate,’ 6 (24%) were ‘inaccurate,’ and 0 (0%) were ‘unreliable.’ Questions about definition, prevalence, hearing rehabilitation, diagnosis and treatment were found to be more accurate than the average, while causes and prognosis were less accurate than the average.Conclusion The information on sudden sensorineurla hearing loss obatined from ChatGPT was quite accurate. It is expected to provide substantial help to patients and doctors. As medicine and medical artificial intelligence develop together, further research is needed on reliability and accuracy in vaious diseases and fields of otorhinolaryngology-head and neck surgery.
Удосконалення підходу до організації і здійснення контролю за використанням (освоєнням) ресурсів у Збройних Силах України в період дії правового режиму воєнного стану
Authors: Loishyn Anatolii , Ulianov Kostyantin
Published: July 2023

Мета роботи: є формулювання обґрунтованих пропозицій щодо удосконалення наявного підходу до організації і здійснення контролю за використанням (освоєнням) переданих в оперативне управління майна і ресурсів військовим частинам і підрозділам Збройних Сил України в умовах правового режиму воєнного стану.

Метод дослідження: методи декомпозиції, аналізу і синтезу.

Результати дослідження: запропоновано авторський підхід до організації і проведення контрольних заходів у Збройних Силах України, а саме розроблено варіант практичного комплексного підходу до організації заходів із контролю за використанням ресурсів новосформованих бригад бойового складу Збройних Сил України.

Теоретична цінність дослідження: полягає в удосконаленні понятійного апарату та процесу підготовки вихідних даних для формулювання принципів реалізації контрольної функції у Силах оборони України щодо контролю і моніторингу використання ресурсів і майна у період дії правового режиму воєнного стану.

Цінність дослідження: в удосконаленні методичних підходів до організації і здійснення контролю за використанням (освоєнням) ресурсів у Збройних Силах України у період дії правового режиму воєнного стану.

Тип статті: теоретична.
Quem é o coordenador pedagógico na educação profissional da rede estadual de ensino do Rio Grande do Norte: uma análise documental
Authors: Ferreira Luis Claudio Machado , Henrique Ana Lúcia Sarmento
Published: July 2023

A coordenação pedagógica pode ser desempenhada por um professor licenciado, graduado em pedagogia, ou em nível de pós-graduação, conforme expressa a LDB nº 9394/1996. Portanto, o presente artigo, questionando quem é o coordenador pedagógico na educação profissional da rede estadual de ensino do Rio Grande do Norte, visa identificar a quem compete exercer tal função nessa rede. Com uma abordagem qualitativa, a metodologia adotada foi uma análise documental da referida LDB, bem como da Lei Complementar nº 585/2016, que dispõe sobre a Gestão Democrática e Participativa da rede de ensino do estado, assim como da Lei nº 10.049/2016, que aprova o Plano Estadual de Educação (2015-2025), dentre outras. Esse trabalho buscou mostrar como se deu a implantação e efetivação da EP no sistema de educação desse estado, assim como em quais alicerces nasce o profissional e a coordenação pedagógica no contexto da história do curso de pedagogia em suas regulamentações, situando a coordenação pedagógica na rede estadual de ensino, a quem compete exercer tal função e suas referidas atribuições. A análise da legislação local mostrou que a coordenação pedagógica é cargo de confiança indicado pelo diretor da escola. Além disso, não se observa, dentre o que se concebe sobre essa coordenação e as diversas atribuições propostas por Lei, a peculiaridade de uma formação e atribuição na e para a atuação na EP, sendo, por vezes, tratado de forma subsumida com o termo genérico de “profissionais da educação”.
A estética e harmonização orofacial
Authors: Teodoro Rosana Aparecida de Almeida , Suguihara Roberto Teruo , Muknicka Daniella Pilon
Published: July 2023

O processo de envelhecimento afeta todas as estruturas do rosto, porém, o início e a velocidade das alterações variam entre cada estrutura específica, indivíduo e grupos étnicos distintos. Portanto, o conhecimento da anatomia relacionada ao envelhecimento é crucial para o trabalho de um especialista em harmonização orofacial, ao realizar um procedimento visando restaurar as estruturas faciais e proporcionar uma aparência mais jovem. Esta revisão tem como objetivo o entendimento atual da anatomia facial humana e busca esclarecer as transformações que ocorrem nos ossos, ligamentos, músculos, gordura e pele durante o envelhecimento. Além disso, destaca-se o papel desempenhado pelo profissional na área de harmonização orofacial nos tratamentos rejuvenescedores, incluindo o uso de toxina botulínica e preenchedores faciais, com ênfase no ácido hialurônico.
ARABULUCULUK SÜRECİNDE TAPU SİCİLİNE TASARRUFU KISITLAYICI ŞERH KONULMASI
Authors: BADUR Emel , KURT KONCA Nesibe
Published: July 2023

Yakın tarihli bir yasama faaliyetiyle Hukuk Uyuşmazlıklarında Arabuluculuk Kanunu’na (HUAK) 17/B maddesi eklenmiştir. Eklenen madde ana hatlarıyla taşınmazın devrine ve taşınmaz üzerinde sınırlı ayni hak kurulmasına ilişkin uyuşmazlıkların arabuluculuk yoluyla çözümlenmesini konu almaktadır.

Arabuluculuk faaliyeti devam ederken, yaşanması muhtemel hak kayıplarının önüne geçilmesi amacıyla, taraflara tapu siciline şerh konulmasını sağlama imkanı da tanınmıştır. Bu şerhin konulabilmesi için taşınmazın aynına ilişkin bir uyuşmazlığın çözülmesi amacına yönelmiş ve devam eden bir arabuluculuk faaliyeti bulunmalı; uyuşmazlığın tarafları şerhe dair yazılı bir anlaşma yapmalı; arabulucu hazırladığı bir tutanakla tarafların şerh sözleşmesini belgelemeli ve tapu siciline şerh talebinde bulunmalıdır.

Açıklanan yöntemle konulan şerh, arabuluculuk süreci devam ettiği sürece ve en fazla konulduğu tarihten itibaren üç aylık bir süre için etkiye sahiptir. Arabuluculuk sürecinin son bulması, tarafların şerhin kaldırılması konusunda anlaşması veya sürenin dolması şerhin etkisini sonlandırır. Eklenen maddedeki şerh, Türk Medeni Kanunu dışında yer alan, yeni bir tasarruf yetkisi kısıtlaması şerhinin, HUAK kapsamında düzenlenmesi olarak nitelendirilmelidir.
Analisis Semiotika pada Cerpen Kontemporer Megatruh Karya Danarto
Authors: Wardhani Aldha Kusuma , Wilyanti Liza Septa
Published: July 2023

Penelitian dalam jurnal ini dilakukan dengan tujuan yaitu untuk mendeskripsikan makna denotasi dan makna konotasi yang terdapat pada cerpen kontemporer berjudul Megatruh yang terdapat dalam kumpulan cerpen Adam Marifat karya Danarto. Cerpen kontemporer didefinisikan sebagai salah satu bentuk dari protes terhadap permasalahan-permasalahan yang muncul dan dimulai sejak awal era industrialisasi. Adapun jenis pendekatan yang digunakan dalam jurnal ini yaitu berupa pendekatan kualitatif dengan metode deskriptif yang dilakukan dengan cara dengan menghimpun dan menganalisis seluruh dokumen berdasarkan kajian teori semiotika Roland Barthes yang telah dipilih. Dokumen yang dimaksud yaitu cerpen Megatruh karya Danarto. Dokumen yang sudah diperoleh kemudian dianalisis berdasarkan struktur fisik dan struktur batin serta dipadukan sehingga menjadi satu hasil kajian yang sistematis dan utuh. Dapat ditarik kesimpulan bahwa hasil penelitian makna denotasi dan makna konotasi yang terdapat pada cerpen kontemporer berjudul Megatruh yang terdapat dalam kumpulan cerpen Adam Marifat karya Danarto yaitu, (1) makna denotasi dan makna konotasi hampir terdapat diseluruh halaman cerita, dengan beberapa bagian kalimat yang tampak lebih menonjol, (2) cerpen mendeskripsikan tokoh utama yang menikmati kegiatannya dengan kadal, batang pisang, dan zat asam, yang sebenarnya merupakan imajinasi terakhir sebelum ia dijemput oleh ajalnya, (3) cerpen ini menceritakan kehidupan seseorang pada detik detik terakhir sebelum roh dan raganya terpisah oleh kematian.
Canira Malolo: An Alternative Treatment for Striae Gravidarum in Postpartum Mothers - A Pre-Experimental Study
Authors: Mariana Dina , Haninggar Rizki Dyah , Nurdiana Nurdiana , Saputri Arwinda  Dwi , MD Nurul Zamzani , Madanyah Al , Hasnaria Hasnaria , Armalia Sri
Published: July 2023

Introduction: Postpartum women have several problems both physiologically and psychologically. Physiological changes during pregnancy often cause problems during the puerperium, one of which is skin problems, namely striae gravidarum. Purpose: To make Canira Malolo spread from Cacao, Virgin Coconut Oil, and aloe vera, and to know the Effectiveness of Canira Malolo against striae gravidarum in postpartum mothers in Polewali Mandar Regency. Methods: This study used a pre-experimental study design with the one group pre-test – post-test design. The sample size is 10 people using purposive sampling technique with inclusion criteria: Postpartum women who have striae gravidarum on the abdomen, have no history of oil allergies, have no open wounds and are willing to become research samples. Data analysis used the Wilcoxon Signed Ranks Test. The study was conducted in May – December 2022. Results: The results showed that Canira Malolo's intervention was effective in reducing the appearance of striae gravidarum in postpartum mothers with a p value=0.025. Conclusion: Canira Malolo made from cacao, virgin coconut oil, and aloe vera can be used as an alternative for treating Striae Gravidarum in postpartum mothers.
Formation and structural features of micelles formed by surfactin homologues
Authors: Bochynek Michał , Lewińska Agnieszka , Witwicki Maciej , Dębczak Agnieszka , Łukaszewicz Marcin
Published: July 2023

Surfactin, a group of cyclic lipopeptides produced by Bacillus subtilis, possesses surfactant properties and is a promising natural and biologically active compound. In this study, we present a comprehensive characterization of surfactin, including its production, chromatographic separation into pure homologues (C12, C13, C14, C15), and investigation of their physicochemical properties. We determined adsorption isotherms and interpreted them using the Gibbs adsorption equation, revealing that the C15 homologue exhibited the strongest surface tension reduction (27.5 mN/m), while surface activity decreased with decreasing carbon chain length (32.2 mN/m for C12). Critical micelle concentration (CMC) were also determined, showing a decrease in CMC values from 0.35 mM for C12 to 0.08 mM for C15. We employed dynamic light scattering (DLS), transmission electron microscopy (TEM), and density functional theory (DFT) calculations to estimate the size of micellar aggregates, which increased with longer carbon chains, ranging from 4.7 nm for C12 to 5.7 nm for C15. Furthermore, aggregation numbers were determined, revealing the number of molecules in a micelle. Contact angles and emulsification indexes (E24) were measured to assess the functional properties of the homologues, showing that wettability increased with chain length up to C14, which is intriguing as C14 is the most abundant homologue. Our findings highlight the relationship between the structure and properties of surfactin, providing valuable insights for understanding its biological significance and potential applications in various industries. Moreover, the methodology developed in this study can be readily applied to other cyclic lipopeptides, facilitating a better understanding of their structure-properties relationship.
Feasibility of exercise therapy for children with asthma: a meta-analysis
Authors: Zhou Linyuan , Xu Haofu
Published: July 2023

Background: Although numerous studies have demonstrated the clear benefits of exercise for people with asthma, controversy remains. This study evaluated the effects of sustained exercise types on lung function and quality of life in patients with asthma.

Methods: We searched PubMed, EMBASE, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), and Wanfang database since January 2000 to August 2022 .included randomized controlled trials (RCTs) of asthmatic children intervened with exercise. The outcomes were lung function and asthma-related quality of life. Fixed-effects model (I2≤50%) or random-effects model (I2>50%) was applied to calculate the pooled effects. Funnel plots were quantified to present publication bias, and a P value <0.05 was statistically significant.

Results: Eventually, 15 trials conformed to the selection criteria. The exercise group significantly improved lung function (FEV1 and FVC) in asthmatic children compared with the control group. Forced Expiratory Volume in 1 Second (MD = 2.12, 95%CI = 0.70, 3.53; p = 0.003; I2 = 15%); Forced Vital Capacity (MD = 2.78, 95%CI = 1.26, 4.31; p = 0.0004; I2 = 56%). The immune system markers IL-6 and TNF-α, were significantly reduced in the exercise group. Interleukin-6 (MD = −0.49, 95%CI = −0.81, −0.17; p = 0.003; I2=0%); tumor necrosis factor-α (MD = −0.54, 95%CI = −0.92, −0.15; p = 0.006; I2 = 0%). That quality of life (PAQLQ) was significantly improved in children with asthma in the exercise group. PAQLQ-Total score (MD = 1.06, 95%CI = 0.46, 1.66; p = 0.006; I2 = 94%); PAQLQ-Emotional (MD = 0.91, 95%CI = 0.76, 1.06; p<0.00001; I2 = 90%); PAQLQ-symptoms (MD = 0.87, 95%CI = 0.71, 1.02; p<0.00001; I2 = 95%); PAQLQ-activities (MD = 1.20, 95%CI = 0.58, 1.82; p = 0.00001; I2 = 93%). Meta-analysis showed significant improvements in body composition in the exercise group. BMI (MD = −2.42, 95%CI = −4.40, 0.44; p = 0.02; I2 = 85%).

Conclusions: This meta-analysis demonstrated the effectiveness of exercise in improving pulmonary function index (FEV1, FVC), immune system (IL-6, TNF-α, Feno), exercise ability (6MWT), body composition (BMI), and quality of life (PAQLQ) in asthmatic children. Asthmatic children should regularly participate in physical exercise.
Co-production of biohydrogen and biomethane utilizing halophytic biomass Atriplexcrassifolia by two-stage anaerobic fermentation process
Authors: Nawaz Ali , Aamir Farheen , Huang Rong , Haq Ikram ul , Wu Fangyu , Munir Marium , Chaudhary Rida , Rafique Ayesha , Jiang Kankan
Published: July 2023

The excessive use of fossil has resulted in the drastic exhaustion of natural energy sources, leading to environmental challenges and energy crises. Owing to rising energy demand there is a dire need to shift towards renewable energies from lignocellulosic biomass. The present study assessed the co-production of biohydrogen (H2) and biomethane (CH4) by utilizing a less explored halophyte Atriplexcrassifolia. Various reaction parameters were evaluated for their effect on biohydrogen and biomethane production in batch experiments. One parameter at a time experimental strategy was chosen for production optimization. Hydrogen and methane yields along with their production rates were assessed at different incubation times, temperatures, pH, substrate concentrations, and inoculum sizes in acidogenesis and methanogenesis stages, respectively. In the first stage, maximum cumulative hydrogen production of 66 ± 0.02 mL, with hydrogen yield of 13.2 ± 0.03 mL/g, and hydrogen production rate (HPR) of 1.37 ± 0.05 mL/h was attained when the reaction mixture (5 g Atriplexcrassifolia and 10 mL pretreated sewage sludge) was processed at 37°C and pH 5.5 after 48 h of incubation. While in the second stage, maximum cumulative methane production, i.e., 343 ± 0.12 mL, methane yield (MY) of 8.5 ± 0.07 mL/mL, and methane production rate (MPR) of 0.8 ± 0.05 mL/h was achieved after 18 days of incubation of reaction mixture (40 mL of hydrogenic slurry with 80 mL inoculum) at 45°C and pH 8. Furthermore, a 51% and 24% rise in biohydrogen and biomethane production respectively were recorded when the gases were produced at these optimized reaction conditions. The results ensure halophyte Atriplexcrassifolia as an imperative renewable energy resource and proposed that effective optimization of the process further increased the coproduction of biohydrogen and biomethane.
Climate change through the essentials–nature's offering and humankind's sine qua non
Authors: Anderl Thomas
Published: July 2023

Climate change is decomposed into the driving terms allowing long-term projection of the natural and economic impacts. As a result, in the case of carbon emissions reduction by 2% per year from the present, the atmospheric CO2 concentration is expected to return to preindustrial values in about 1,000 years, temperature and sea level rise to approximately peak at 1°C and 5 m above the present levels by then, and the entailed economic burden to grow to 1.4% of the current global gross domestic product. Ninety percent of the required emissions reduction are anticipated achievable through cost neutrality. To take advantage of the potentially bearable impact, humankind is obliged to fulfill certain prerequisites near-time: (i) CO2 emissions reduction must be at least 2%/year at global level; (ii) economic growth may not continue to jeopardize emissions reduction efforts, thus far contributing with an emissions rise of 1.7%/year; (iii) due to the economic interlinkage, global coherence of regulatory measures must be established, proposedly commencing with a sizable group of countries, the rules comprising economic penalization of non-participants. The presented insight is associated with the potential to alter the social decision mode.
Serum C-peptide level and the risk of cardiovascular diseases mortality and all-cause mortality: a meta-analysis and systematic review
Authors: Ahmadirad Hamid , Teymoori Farshad , Mokhtari Ebrahim , Jahromi Mitra Kazemi , Norouzzadeh Mostafa , Tavakkoli Saeed , Shahrokhtabar Tahere , Farhadnejad Hossein , Mirmiran Parvin
Published: July 2023

Aims and background

Recently, the serum of C-peptide has been the focus of researchers as a possible predictor of mortality. However, the possible association of serum C-peptide with cardiovascular diseases (CVDs) mortality and all-cause mortality has not been clearly identified. This meta-analysis aimed to assess the relationship between serum C-peptide and the risk of CVDs mortality and all-cause mortality.

Methods

A comprehensive and systematic search was performed in various important databases, including the PubMed, Web of Science, and Scopus to find relevant studies up to November 2022. The reported hazard ratio (HR) [95% confidence interval (CI)] for all studies was converted into log HR, and their SD was calculated. Then to compute the pooled HR, the random-effects model with inverse variance weighting method was performed.

Results

Twenty-three studies were included in the meta-analysis. Fourteen studies reported HR for all-cause mortality, and nine studies for CVDs-related mortality. The pooled results indicate a significant association between serum C-peptide and the risk of all-cause mortality (HR: 1.22; 95% CI: 1.12–1.32, I2 = 76.8%; P-value < 0.001). Also, higher serum C-peptide was related to the increased risk of CVDs mortality (HR: 1.38; 95% CI: 1.08–1.77, I2 = 81.8%; P-value = 0.012).

Conclusions

Our investigation suggested that an increased level of serum C-peptide is associated with a higher risk of both CVDs and all-cause mortality. Further, large-scale studies and sufficient samples are recommended to present a convincing link between C-peptide and the risk of CVDs and all-cause mortality.

Systematic Review Registration

identifier, CRD42022364842.
Tree-based survival analysis improves mortality prediction in cardiac surgery
Authors: Penny-Dimri Jahan C. , Bergmeir Christoph , Reid Christopher M. , Williams-Spence Jenni , Perry Luke A. , Smith Julian A.
Published: July 2023

Objectives

Machine learning (ML) classification tools are known to accurately predict many cardiac surgical outcomes. A novel approach, ML-based survival analysis, remains unstudied for predicting mortality after cardiac surgery. We aimed to benchmark performance, as measured by the concordance index (C-index), of tree-based survival models against Cox proportional hazards (CPH) modeling and explore risk factors using the best-performing model.

Methods

144,536 patients with 147,301 surgery events from the Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) national database were used to train and validate models. Univariate analysis was performed using Student's T-test for continuous variables, Chi-squared test for categorical variables, and stratified Kaplan-Meier estimation of the survival function. Three ML models were tested, a decision tree (DT), random forest (RF), and gradient boosting machine (GBM). Hyperparameter tuning was performed using a Bayesian search strategy. Performance was assessed using 2-fold cross-validation repeated 5 times.

Results

The highest performing model was the GBM with a C-index of 0.803 (0.002), followed by RF with 0.791 (0.003), DT with 0.729 (0.014), and finally CPH with 0.596 (0.042). The 5 most predictive features were age, type of procedure, length of hospital stay, drain output in the first 4 h (ml), and inotrope use greater than 4 h postoperatively.

Conclusion

Tree-based learning for survival analysis is a non-parametric and performant alternative to CPH modeling. GBMs offer interpretable modeling of non-linear relationships, promising to expose the most relevant risk factors and uncover new questions to guide future research.
Antihypertensive medication use during pregnancy in a real-world cohort of patients diagnosed with a hypertensive disorder of pregnancy
Authors: Garcia Julian E. , Mulrenin Ian R. , Nguyen Anh B. , Loop Matthew S. , Daubert Melissa A. , Urrutia Rachel , Lee Craig R.
Published: July 2023

Hypertensive disorders of pregnancy (HDP) are rising in prevalence and associated with adverse maternal and infant health outcomes. Current guidelines recommend labetalol, nifedipine, and methyldopa as acceptable first-line agents to treat HDP in outpatient settings. However, the current practice regarding antihypertensive medication usage and selection remain unclear. A retrospective, observational cohort study was conducted in 1,641 patients with a physician diagnosis of HDP who delivered at two academic medical centers in North Carolina from 2014 to 2017. Use of any antihypertensive medication, and the agent selected, at any encounter during pregnancy or on the delivery date was collected from the electronic health record. Proportions were compared across HDP diagnosis (eclampsia/severe preeclampsia, chronic hypertension with superimposed preeclampsia, preeclampsia, gestational hypertension) by Chi-square tests and multivariable logistic regression. Antihypertensive medications were used in 1,276 (77.8%) patients overall. Among treated patients, labetalol (74.9%) was the most frequently used medication followed by nifedipine (29.6%) and hydralazine (20.5%). Methyldopa was used infrequently (4.4%). HDP type was the strongest factor associated with use of an antihypertensive agent. Relative to gestational hypertension, antihypertensive use was significantly more likely [odds ratio (95% CI)] in patients with severe preeclampsia [5.94 (3.85–9.16)], chronic hypertension with superimposed preeclampsia [4.99 (3.46–7.19)], and preeclampsia [2.13 (1.61–2.82)]. In a real-world setting, antihypertensive medication use among HDP patients was common, labetalol, nifedipine, and hydralazine were the most commonly selected agents, and increasing HDP severity was associated with a higher likelihood of antihypertensive use. Future studies comparing medication effectiveness in pregnant patients with distinct HDP diagnoses are needed.