bluuebunny/crossref_metadata_2025 huggingface dataset:
СЫРА ӨНДІРУГЕ АРНАЛҒАН ЖАҢА АШЫТҚЫ ШТАММЫ
Authors: AKHMETZHANOVA А.К. , BAIGAZIEVA G.I. , KEKIBAEVA А.K. , HRYVNA L.
Published: December 2023

To improve the properties of yeast used in brewing and winemaking, scientists have widely used the methods of classical genetics. The research is devoted to the focus of the work is on strains of brewer's yeast Saccharomyces cerevisiae, capable of fermenting beer wort most effectively and having no organoleptic deficiencies. The object of the study is 6 strains of Saccharomyces cerevisiae yeast from Federal State Unitary Enterprise «State Research Institute of Genetics and Selection of Industrial Microorganisms» (http://www.genetika.ru/vkpm). The selected strains were crossed as a result of using a selective selection system for rare hybrid clones. Production tests of one of the clones of the resulting strain showed positive outcome. Using new yeast strain will solve three main tasks of brewing - to improve the consumer properties of the drink, the technological parameters of production and the stability of the finished product during storage. The versatility of the strain will allow the use of these yeasts in the production of other beers.

Сыра қайнату мен шарап жасауда қолданылатын ашытқының қасиеттерін жақсарту үшін ғалымдар классикалық генетика әдістерін кеңінен қолданады. Жұмыс Saccharomyces cerevisiae сыра ашытқысының штаммдарын таңдауға арналған, ол сыра суслосын тиімді ашытуға қабілетті және органолептикалық кемшіліктері жоқ. Зерттеу нысаны - «Өндірістік микроорганизмдердің генетикасы және селекциясы мемлекеттік ғылыми-зерттеу институты» Федералдық мемлекеттік унитарлық кәсіпорны (ӨМБК). Бүкілресейлік коллекциясынан Saccharomyces cerevisiae ашытқысының 6 штамм алынды. Таңдалған штаммдардың ішінен сирек кездесетін гибридті клондарды іріктеудің селективті жүйесін қолдану нәтижесінде будандастыру жүргізілді. Алынған штамм клондарының бірінің өндірістік сынақтары жақсы нәтиже көрсетті. Жаңа штаммды қолдану сыра қайнатудың үш негізгі міндетін шешуге мүмкіндік береді:сусынның тұтынушылық қасиеттерін, өндірістің технологиялық параметрлерін және сақтау кезінде дайын өнімнің тұрақтылығын жақсарту. Штаммның әмбебаптығы бұл ашытқыны басқа сыра өндірісінде қолдануға мүмкіндік береді.
СРАВНИТЕЛЬНАЯ ДИАГНОСТИКА ПРИ ИНФЕКЦИОННОМ И ИНВАЗИОННОМ КЕРАТОКОНЪЮНКТИВИТАХ КРУПНОГО РОГАТОГО СКОТА
Authors: SATTAROVA R.S. , STROCHKOV V.M. , BORANBAEVA K.E. , ZAMANBEKOV N.A. , BAKIEVA F.А. , SHYNYBAEV K.M. , OSPANOVA M.S. , SMAN K. , SPIRIDONOV G.N.
Published: December 2023

The article presents the results of comparative studies in infectious and invasive keratoconjunctivitis of cattle for 2023. 542 conjunctival samples of cattle from economic entities of Akmola, Zhetysu, Turkestan and Kostanay regions were studied. Real-time polymerase chain reaction was carried out with a set of «PCR-Moraxella-RV» reagents to identify three causative agents of Pink eye - Moraxella bovis, Moraxella ovis, Moraxella bovoculi. 15 positive samples from the Akmola region were identified as Moraxella bovoculli (100%), 33.3% were identified as Moraxella ovis,and 6.7% were identified as Moraxella bovis. During a microscopic examination of conjunctival swabs from the same animals, thelazias were dedected in 224 samples, which amounted to 43.1%.

В статье приводятся результаты сравнительных исследований при инфекционном и инвазионном кератоконъюнктивитах крупного рогатого скота за 2023 год. Было исследовано 542 конъюнктивальных смывов крупного рогатого скота хозяйствующих субъектов Акмолинской, Жетысуской, Туркестанской и Костанайской областей. Полимеразно-цепная реакция в режиме реального времени проводилась набором реагентов «ПЦР-Моракселла-РВ» для выявления трех возбудителей моракселлеза - Moraxella bovis, Moraxella ovis, Moraxella bovoculi. В 15 положительных пробах из Акмолинской области, идентифицированных как Moraxella bovoculli (100%), 33,3% опознаны как Moraxella ovis, а 6,7% – Moraxella bovis. При микроскопическом исследовании конъюнктивальных смывов от этих же животных, телязии были обнаружены в 224 пробах, что составило 41,3%.
ОКулировочная галлица Resseliella oculiperda(Rübsaamen, 1893) (Diptera, Cecidomyiidae) – НОВЫЙ ПЕРЕНОСЧИК ВОЗБУДИТЕЛЯ БАКТЕРИАЛЬНОГО ОЖОГА (ERWINIA AMYLOVORA) ПЛОДОВЫХ
Authors: TEMRESHEV I.I. , KOPZHASSAROV B.K. , Beknazarova Z.B. , SarbasSova A.M. , SADANOV A.K. , ISMAILOVA E.T. , MOLZHIGITOVA А.Е. , YAKOVLEV R.V.
Published: December 2023

Red bud borer Resseliella oculiperda, a pest of many fruit crops, is a new vector of the causative agent of bacterial fruit blight Erwinia amylovora in Kazakhstan. It was confirmed using PCR analysis of its larvae and puparia collected from apple trees of the Aport variety in two peasant farms at different times. The spread of infection with the help of R. oculiperda can go in several ways: 1) with the development of gall midge larvae in the branches of infected trees, the imago, after emerging from the puparium, can carry the spores of the pathogen on itself to other plants; 2) when females lay eggs in tree branches (females lay eggs in fresh mechanical damage (wounds, cracks, and scratches) of the bark on the trunk, shoots and branches, buds and eyes); 3) when gall midge larvae make passages during feeding, the infection can penetrate the resulting lesions with wind, rain, and other insects penetrating the passages of larvae; 4) introduction of bacteria by gall midge larvae from contaminated soil. In Kazakhstan, methods for controlling the number of budding gall midges have not been developed, and at present the actual distribution of the pest in the territory of the republic is unknown. Since R. oculiperda is a vector of such a dangerous quarantine disease as the bacterial blight of fruit, further research in this direction is necessary to clarify the missing information.

Окулировочная галлица Resseliella oculiperda, вредитель многих плодовых культур, является новым переносчиком возбудителя бактериального ожога плодовых Erwinia amylovora в Казахстане. Это подтверждено с помощью ПЦР-анализа её личинок и пупариев, собранных на яблонях сорта Апорт в двух крестьянских хозяйствах в разное время. Распространение инфекции с помощью R. oculiperda может идти несколькими путями: 1) при развитии личинок галлицы в ветвях зараженных деревьев – имаго после выхода из пупария может уносить споры возбудителя на себе на другие растения; 2) при откладке яиц самками в ветви деревьев (самки откладывают яйца в свежие механические повреждения (ранки, трещины и царапины) коры на стволе, побегах и ветвях, почки и глазки); 3) при прокладке ходов личинками галлицы во время питания – в образовавшиеся повреждения инфекция может проникнуть с ветром, дождем, другими насекомыми, проникающими в ходы личинок; 4) занос бактерий личинками галлицы из зараженной почвы. В Казахстане методы контроля численности окулировочной галлицы не отработаны, и в настоящее время неизвестно фактическое распространение вредителя на территории республики. Поскольку R. oculiperda является переносчиком такого опасного карантинного заболевания, как бактериальный ожог плодовых, необходимы дальнейшие исследования в этом направлении для уточнения отсутствующей информации.
МҰНАЙТОТЫҚТЫРУШЫ БАКТЕРИЯЛАР НЕГІЗІНДЕГІ БИОСОРБЕНТТІҢ ДЕСТРУКТИВТІ БЕЛСЕНДІЛІГІН ЗЕРТТЕУ
Authors: MAKHATAYEVA B.B. , UALIEVA P.S. , ABDIEVA G.Zh. , ONGARBAYEV E.K. , NURMAGANBETOVA A.S.
Published: December 2023

The growth activity of oil oxidizing microorganism strains in the oil-contaminated areas and the efficiency of oil decomposition were studied. During the experiment, a microbial consortium was formed using selected strains of microorganisms which were then immobilized in sorbents made of carbonized shungite and rice husks. A biosorbent based on a consortium of microorganisms, Pseudomonas poae TM1, and Pseudomonas migulae TM2, along with carbonized shungite and rice husks, has shown promising results in the bioremediation of oil-contaminated areas.

Мұнай тотықтырушы микроорганизм штамдарының мұнаймен ластанған аймақта өсу белсенділігі және мұнайды ыдырату белсенділігі зерттелді. Тәжірибе барысында таңдалып алынған микроорганизм штамдарынан микробтық консорциум құрастырылып көміртектендірілген шунгит және күріш қауыздарынан жасалған сорбенттерге иммобилизация жасалды. Pseudomonas poae TM1 және Pseudomonas migulaе TM2 микроорганизмдер консорциумына және көміртектендірілген шунгит пен күріш қауызына негізделген биосорбент мұнаймен ластанған аймақтарды биоремедиациялауда перспективті екендігін көрсетті.
MODERN DİN ALGISI: AHLAKİ TERAPÖTİK DEİZM
Authors: ÖZALP Ahmet
Published: December 2023

Deizm olgusu günümüzde din bilimleri alanında çokça tartışılan konulardan biridir. Bu bağlamda deizmin mahiyeti ve tarihi seyri akademik çalışmalarda sıkça tartışılmakta araştırmacılar tarafından bu konu üzerinde fikir birliğine varılamamaktadır. Deizm konusu akılcılığın ve reform hareketlerinin ortaya çıkışından itibaren gün yüzüne çıkmaya başlamıştır. Deizmin mahiyeti ve tarihi serüveni tartışılmadan deizm hakkında yapılacak bir çalışma konunun tam anlamı ile anlaşılmasını imkânsız kılmaktadır. Deizmin temel iddiaları ve tarihi gelişimi incelendikten sonra ülkemizde ve dünyada yaygınlaşması üzerine durulacaktır. Son olarak Ahlaki Terapötik Deizm kavramı incelenip bu konudaki tartışmalar değerlendirilecektir. Bu makale resmi istatistiki verilerden de yararlanılarak literatür tarama tekniğine göre yapılmıştır. Çalışmanın temel amacı deizmin tarihi süreçte aldığı şekilleri ortaya koymak, ülkemizde ve farklı coğrafyalarda deizmin yaygınlaşmasının altında nedenleri bulmak ve günümüzde gençler arasında etkili olan ATD’i araştırmaktır. Çalışma bu haliyle ülkemizde hakkında yeterli kaynak bulunmayan ATD konusu özelinde literatüre zenginlik katacaktır. Çalışma sonucuna göre, modern deizme yöneliş ülkemizde ve Batı toplumlarında artış göstermektedir. Ek olarak, kendini deist olarak tanımlamayan belirgin yetişkinler yaşam tarzı ve inanç şekli açısından ahlaki terapötik deistik inançlara yönelmektedirler. Gençler bu yaklaşıma göre sorunlarla karşılaştıklarında dua ve ibadet etmekte ancak kişisel işleri ve yaşamlarına kurumsal dinin taleplerinin müdahalesini istememektedirler. Gençler, ahlaki anlamda iyi olan insanların hangi dine mensup olurlarsa olsunlar cennete gideceklerine inanmakta ve temel dini öğretilere uzak durmaktadırlar. ATD Hıristiyan Batı toplumlarında yaygınlaşan ahlaki terapötik deistik yaklaşımın Türkiye’de de gider etkili olmaya başladığı anlaşılmaktadır.
Intern Nurses’ Experiences and Attitudes Towards the Concept of Death While Providing Care for Cancer Patients: A Descriptive and Cross-Sectional Study
Authors: AYTUR ÖZEN Tangül , ERDEM Cigdem
Published: December 2023

Aim: This study was conducted using a descriptive and cross-sectional method to determine the attitudes and experiences of intern nursing students toward the concept of death while providing care for individuals with cancer.
Methods: The sample of the study consists of 94 intern nurse students. The data were collected through face-to-face interviews using the data form including questions about sociodemographic characteristics and the concept of death, and the Frommelt Attitude Towards Care of the Dying Instrument. Descriptive statistics, Mann Whitney U and Kruskal-Wallis tests were used in the analysis of the data.
Results: Of the students 91.5% encountered the concept of death outside the clinical environment, while 70.2% encountered in the clinical setting, and 58.5% provided care for five or more dying patients. Of the students 67.1% had difficulties in the interviewing and data collection process, and 22.3% had difficulties in all nursing practices. 47.3% said they experienced helplessness, and 19.7% said they experienced grief. In the current study, it was found that the mean FATCOD score was 73.00 ± 8.70. There was a difference in the scale scores in terms of the students' status of feeling comfortable talking to a cancer patient about the concept of death (p<0.05).
Conclusions: Intern nursing students have experienced helplessness. Students need strategies focusing on all stages of the nursing process in both theoretical and clinical practice.
Emotional Reactivity and Death Anxiety in Dialysis Patients
Authors: UZDİL Nurcan , KILIÇ Züleyha , ŞİMŞEK Nuray
Published: December 2023

Aim: This study was conducted as a correlational and comparative pilot study to determine the relationship between emotional reactivity and death anxiety in dialysis patients.
Method: The study was conducted with a total of 140 people, including 70 hemodialysis (HD) and 70 peritoneal dialysis (PD) patients. A questionnaire form, Turkish Death Anxiety Scale (TDAS) and Emotion Reactivity Scale (ERS) were used for data collection.
Results: There was no difference between the mean ERS and TDAS scores of hemodialysis and peritoneal dialysis patients. A moderate positive correlation was found between the mean ERS and TDAS scores in HD and PD groups (p<0.05). It was determined that 15.3% of TDAS scores of hemodialysis patients and 26.2% of TDAS scores of PD patients are explained by ERS.
Conclusion: It was observed that death anxiety and emotional reactivity were at a moderate level in hemodialysis and peritoneal dialysis patients and there was a similarity between dialysis modalities.
Bibliometric and Visual Analysis of Elbow Tendinosis Research in Orthopaedic Surgery
Authors: ÜZÜMCÜGİL Alaaddin
Published: December 2023

Aim: Elbow tendinosis is the most frequent cause of elbow discomfort. The disease is common in the daily routine practice of sports medicine and orthopedics. However, currently, this issue lacks a multifaceted, methodical, and understandable visual examination.
Materials and Methods: Utilizing the Biblioshiny program, the core collection dataset of the Web of Science database's literature on elbow tendinosis from 1970 to April 2023 was compiled and examined. Research hotspots and development patterns were examined in terms of highly influential authors, research institutions, nations or regions, keywords, and referenced publications.
Results: According to the search criteria, 526 articles were published by 1817 authors from 839 affiliations, and 47 countries in the Web of Science database. The amount of articles on elbow tendinosis has increased over time, especially after 2000. 55.6% of all articles were published in 2010 and later years. The articles included in this study were published in the United States (n=152, 28.843%), England (n=43, 8.159%), Germany (n=40, 7.59%), Turkey (n= 40, 7.59%) and South Korea (n=28, 5.313%). The United States had the highest total citation number 4493, but Canadian publications had the highest number of average article citations (56.4).
Conclusion: Although studies on elbow tendinosis in the field of orthopedics have gained momentum in recent years, they are still insufficient. Although the United States ranks first in terms of publications, it is pleasing for our country that Turkey ranks high.
Bibliometric Analysis of Studies on Postoperative Delirium: A Web of Science Database Example
Authors: SALTALI Ali Özgül
Published: December 2023

Aim: Postoperative delirium is a complication that occurs acutely after surgical procedures, especially in elderly patients. The aim of this study is to scientifically analyze the publications on postoperative delirium.
Method: For the purpose of the research, articles on postoperative delirium published in the Web of Science (WoS) Core database were analyzed using scientific mapping methodology. The articles were scanned in the “postoperative delirium” word group in the WoS database, and the obtained data were analyzed with the VOSViewer 1.6.19 program.
Results: It was seen that the most used keywords related to postoperative delirium have been delirium (n=1131), postoperative delirium (n=444), elderly (n=209), cardiac surgery (n=199), hip fracture (n=184). On the subject of postoperative delirium, Edward R Marcantonio was the author with the most publications with 83 articles, and Harvard Medical School was determined as the institution with the most publications with 142 publications.
Conclusion: The number of publications on postoperative delirium has increased especially in the last ten years. While this situation shows the importance of postoperative delirium in anesthesia studies, it is important that researchers who have published in recent years on postoperative delirium have been from different countries.
Revisiting Vitruvius’ Town Planning Method in Architectural Education
Authors: Andri Yatmo Yandi , Atmodiwirjo Paramita
Published: December 2023

This paper discusses the method of town planning described in Vitruvius’ Ten Books on Architecture and explores the possibility of its application in the process of design learning in architectural education. In particular, it addresses the prescriptive nature of the texts that outlined the method of town planning as an example of contextual strategies to highlight the key aspects of the design methodology to be followed in a structured manner. To explore the extent to which this method is applicable in a real design process, Vitruvius’ texts on town planning became the basis for method exploration in a class of undergraduate architectural education. The exercise of developing a set of town plans following the principles highlighted in the texts demonstrates the robustness of the methods outlined by Vitruvius. Revisiting Vitruvius’ methods through this exercise becomes a way to understand and rethink the position of Vitruvius’ texts within current architectural practice and education.
Perfil epidemiológico de casos notificados de acidentes que envolvem animais peçonhentos ocorridos nos municípios do Estado do Amazonas, período de 2017 a 2022
Authors: de Castro Flavia Sabrina Araújo , Barroso Livia Carvalho , Cavalcante Mário Jorge da Silva , De Almeida Rayane Silva , de Sousa Dayane Priscila Costa , Cunha Linda Karolinne Rodrigues Almeida , Coêlho Prisca Dara Lunieres Pêgas , Figueiredo Silvana Nunes , Dos Santos Enock Barroso
Published: December 2023

Introdução: Acidentes envolvendo animais peçonhentos são eventos que requerem notificação compulsória no Brasil que representam um grande problema de saúde pública. Objetivo: Descrever o perfil sociodemográfico dos acidentes por animais peçonhentos notificados no estado do Amazonas no período de 2017 a 2022. Metodologia: Trata-se de um estudo epidemiológico descritivo de abordagem quantitativa com dados obtidos por meio do Sistema de Informação de Agravos Notificáveis (SINAN), armazenado no sistema do departamento de informática do Sistema Único de Saúde do Brasil (DATASUS e bases demográficas do Instituto Brasileiro de Geografia e Estatística (IBGE). Para análise foram feitas as taxas de incidência e frequências relativas e absolutas. Resultados: Foram notificados no Amazonas, no período de 2017 a 2022, 17.920 casos de acidentes por animais peçonhentos. As maiores as taxas de incidência foram de Alvarães 748.05/100mil-hab em 2017, Alvarães 936.64/100mil-hab em 2018, Apuí 602.63/100mil-hab em 2019. O perfil de casos norteia que os indivíduos mais afetados são do sexo masculino com 13.086 (73.02%) dos casos, na faixa-etária de 20 a 39 anos com 6.645 (37.08%), com ensino fundamental incompleto 7.228 (40.33%), pardos 13.231 (73.77%), sendo o pé o local de ocorrência 8.378 (46.75%), de gravidade leve 9.245 (51.59%), 12.155 (67.83) utilizaram soroterapia, com um tempo de atendimento de 1h a 3h 5.136 (28.66%), que evoluíram para cura 16844 (94%). Conclusão: Os acidentes por animais peçonhentos ainda são um grande desafio para a saúde pública para o Amazonas por sua grande ocorrência em áreas e populações vulneráveis.
Üniversitelerin Yeni Medya Bölümlerinin Endüstri 4.0 Bağlamında Teknolojik Formasyon Açısından İncelenmesi
Authors: KARAHİSAR Tüba
Published: December 2023

Eğitim, elli yıl önce müfredatla ve sadece okullarla sınırlanmışken günümüzde hayat boyu öğrenme ile süreklilik arz eden bir konu haline gelmiştir. 1. sanayi devrimi döneminde eğitim sınıfın ortalamasına göre planlanırken günümüzde ise kişiselleştirilmiş ve her öğrenciye özel eğitim verilmesi planlanmaktadır. İş yapma şekillerinin değişmesi ve sanayi 4.0 ile birlikte artık “bilmek” yetmemekte “uygulamak” ön plana çıkmaktadır. Dolayısıyla gerek ilk ve orta öğrenim gerekse üniversite öğreniminde bugünün iş yapma biçimlerine uygun bir müfredat hazırlanması hâsıl olmuştur. Çünkü gelecekte medya endüstrisi, endüstri 4.0 ile bağlantılı olarak sadece bilen değil uygulayabilen bireyleri istihdam edecektir.

Bu çalışmada Türkiye’deki üniversitelerin çeşitli fakültelerinde yer alan yeni medya ve iletişim bölümlerinin müfredatları teknolojik formasyon açısından incelenerek müfredattaki derslerin teorik ve uygulamalı dersler yönünden araştırılması hedeflenmiştir. İletişim fakülteleri içinde yer alan gazetecilik ve radyo televizyon sinema bölümleri yıllardır eğitim verirken yeni medya bölümü, mazisi diğerleri kadar eski olmayan ve uygulamalı derslerin fazla olması beklenen bir bölümdür. Çalışmada yeni medya bölümü bu sebeple seçilmiştir.

Makalede öncelikle Türkiye’de üniversitelerin çeşitli fakültelerindeki yeni medya ya da yeni medya ve iletişim bölümlerinin dökümü yapılmıştır. Örneklem, 7 farklı ilden birer örneklem almak suretiyle gerçekleştirilmiştir. Araştırmanın sonucuna göre devlet ve vakıf üniversiteleri bağlamında vakıf üniversiteleri lehine bir dengesizlik gözlemlenmektedir. Uygulamalı derslerin yapıldığı atölye, laboratuvar ve stüdyo olanakları üniversiteler arasında oldukça farklılık göstermektedir.
Presentazione
Authors: Scaramuzza Gabriele , Borutti Silvana
Published: December 2023

-
Giordano Bruno e la civiltà europea
Authors: Bellini Manuele
Published: December 2023

According to Fulvio Papi, Giordano Bruno defends European culture by countering the “myth of the noble savage”, fuelled, in the modern age, by the discovery of America and supported, among other things, in Montaigne’s reflections on cannibals. However, Bruno’s is a “moderate Eurocentrism” which not only condemns the violence of the conquistadores, but is also based on a primitive idea of progress: all beings, in fact, are equal from an ontological point of view, since they are born through spontaneous generation, but only human beings, even the savages of the New World, can and must, thanks to manual industriousness, move from nature to civilization, of which European one is the model, however improvable. It is therefore in metaphysics and in the relationship between matter and form that, for Papi, the reasons for Bruno’s conception of European civilization must be sought.
Per Fulvio Papi
Authors: Capelli Ferruccio
Published: December 2023

-
Fulvio Papi, la filosofia come pratica di scrittura
Authors: D'Alessandro Davide
Published: December 2023

-
Il pensiero filosofico e civile di Fulvio Papi
Authors: Minazzi Fabio
Published: December 2023

-
Kafka nel cielo d'autunno
Authors: Scaramuzza Gabriele
Published: December 2023

-
Il coraggio della verità
Authors: Papi Fulvio
Published: December 2023

-
Tra Adorno e Lukács. Un dialogo in casa Einaudi
Authors: Lucchini Guido
Published: December 2023

-
Maria Callas interprete di Wagner
Authors: Scaramuzza Gabriele
Published: December 2023

-
Call for papers Materiali di Estetica 11.1 (giugno 2024) - "L'arte e il sogno"
Authors: Redazione
Published: December 2023

-
Tacrolimus Interaction with Azole Antifungals in Kidney Transplant Recipients: Is Fluconazole or Clotrimazole a Worse Offender?
Authors:   Pharm.D., CPP, Department of Pharmacy, Atrium Health Carolinas Medical Center, Charlotte, NC, United States of America (USA)., Revello Jane , Rao Vinaya ,   MD, Department of Nephrology, Medical University of South Carolina, Charleston, SC, United States of America (USA).,   RPh, MS, Department of Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA, United States of America (USA)., Apple Alison , Krauss Amy ,   PharmD, BCPS, Department of Pharmacy, Gritman Medical Center, Moscow, ID, United States of America (USA)., Duhart Benjamin ,   Jr., MS, PharmD, Department of Clinical Pharmacy and Translational Research, University of Tennessee Health Science Center College of Pharmacy, Memphis, TN, United States of America (USA).
Published: December 2023

The utilization of rabbit ant thymocyte globulin induction with tacrolimus-based maintenance immunosuppression may increase the risk for opportunistic fungal infections, particularly oral-esophageal candidiasis. Both are commonly prescribed for deceased donor kidney transplant recipients Tacrolimus (TAC), a calcineurin inhibitor, is metabolized hepatically by cytochrome P450 3A4/5 enzymes. Due to this, a drug interaction can occur with TAC and either fluconazole (FCZ) or clotrimazole (CTMZ). Both are commonly used for antifungal prophylaxis. While both FCZ and CTMZ inhibit CYP3A4/5, systemic absorption of CTMZ is minimal, theoretically limiting the interaction with TAC and reducing the need for dose readjustments. Medical records for adult patients receiving a renal transplant between March 2009 and September 2011 were retrospectively reviewed for TAC dose adjustments following discontinuation of the antifungal agent required to maintain therapeutic TAC blood levels. The change in TAC dose: trough ratio 4-8 weeks after azole discontinuation was greater in patients receiving FCZ compared to CTMZ (FCZ +92.9% vs CTMZ +43.4%, p=0.004). In addition, the proportion of patients requiring ≥30% TAC dose increase was 70% with FCZ versus 45% with CTMZ (p=0.006). The choice of antifungal also did not affect the number of sub-therapeutic TAC levels, the number of patients with sub-therapeutic levels pre- or post-discontinuation, or incidence of biopsy-proven allograft rejection.
Name System Based on Birth Order as A Balinese Ethnic Identity in Bali Indonesia
Authors:   Religion and Culture, STAHN Mpu Kuturan, Bali, Indonesia., Atmadja Nengah Bawa , Raka Nyoman ,   Religion and Culture, STAHN Mpu Kuturan, Bali, Indonesia., Wija Nyoman ,   Master’s Student of Religion and Culture, STAHN Mpu Kuturan, Bali, Indonesia., Lestari Ni Kadek Melda ,   Master’s Student of Primary School Teacher Education (PGSD), STAHN Mpu Kuturan, Bali, Indonesia.
Published: December 2023

This article results from field research that describes a naming system based on birth order, namely Wayan, Made, Nyoman, and Ketut, as Balinese ethnic identities. Data analysis uses an interaction cycle consisting of various activities: data collection, data reduction, data display, and conclusion drawing and verifying. The research objective is to describe the meaning of the naming system and its changes. The results of the study show that this naming system is not only a Balinese ethnic identity but also has social, cultural, psychological, and religious-magical meanings for the owner of the name. This meaning causes the Balinese to recognize the life cycle ritual of giving a name, namely nelubulanin. This ritual is an obligation for the parents in Bali.
Secularism in India: Exploring its Reality, the 42nd Amendment, and its Relation to Article 370 of the Constitution
Authors:   Research scholar, Kurukshetra university Kurukshetra., Arora Shalu
Published: December 2023

This in-depth study shows how the 42nd Constitutional Amendment and the repeal of Article 370 changed India's secularism. It looks at how secularism has changed India's constitution over time and how it has affected social peace and religious equality. The paper looks at the many ways that the 42nd Amendment has helped India become more open-minded, and it talks about worries and disputes about how it is being put into place. It talks about Indian secularism, religious rights, and the split of church and state. The paper then looks at the temporary parts ofArticle 370 and the political events that led to it being taken away. It looks at how religion and freedom interact with each other in Jammu and Kashmir. The study also compares atheism models from around the world, with a focus on how policy should change depending on the situation. Examining how communalism, identity politics, and social and economic inequality threaten India's democracy in a critical way (Elgin et al., [8][17][18]). The study goes on to look at how India's changing culture is affected by reforms, education, and secularism.
Gender Mainstreaming in Climate Policy: Empowering Women and Reducing Gender Disparities in Post-Disaster Scenarios
Authors:   Department of Political Science, Panjab University, Chandigarh, India., Anuradha  , Saggu Pavittarbir ,   Department of Political Science, Panjab University, Chandigarh, India.
Published: December 2023

Gender mainstreaming involves integrating a gender perspective into various actions, policies, legislations, or initiatives to address the concerns of all individuals and prevent the perpetuation of gender inequalities through institutional channels. Despite its global implementation, gender mainstreaming has not consistently resulted in progress for women; often, it is linked to a scaling back of policies and programs specifically targeting women. Recent research highlights the gendered impacts of climate change, yet efforts to develop mitigation and adaptation strategies have largely neglected gender mainstreaming. Additionally, the predominant scientific and technological focus in institutional responses has overshadowed social outcomes, leading to insufficient attention to vulnerable groups, particularly women. This paper argues for the imperative of gender mainstreaming in climate policy and advocates for policies explicitly centered on women's empowerment. The essence of gender mainstreaming is crucial not only for ensuring the comprehensiveness of climate policies and programs but also for the development of women-focused policies, ensuring that women receive the necessary support and empowerment to take proactive measures on their own behalf.
Ebelikte Yeni Bir Alan: Adli Ebelik
Authors: UYAR HAZAR Hale , BAYAR YILDIRIM Rojda
Published: December 2023

Ebeler anne ve bebeğe aynı anda hizmet eden ve sağlıkları ile ilgili sorumlulukları üzerine alan sağlık çalışanlarıdır. Takipler sırasında anne ve/veya fetüse yönelik istenmeyen (maternal-uterine hiperstimulasyonu, uterus rüptürü, preterm doğum, eklampsi, amniotik sıvı embolisi, postpartum hemoraji, fetal kalp atım düzensizliği, umblikal kord prolapsusu, omuz distosisi gibi) veya acil bir durumla karşılaşıldığında onların zarar görmelerini engellemek için ebelerin gerekli müdahaleleri zamanında yapması gerekmektedir. Ebeler çalışma hayatları süresince adli tıbbi problemlerin bir kısmına sadece tanık olmaktayken, bir kısmını ise aktif olarak yaşamaktadır. Bu nedenle ebelerin kendileri ile ilgili gerekli yasal görev, yetki ve sorumlulukları bilmesi, hukuka uygun müdahalelerde bulunması gerekmekte ve Adli Ebelik alanında eğitim almış uzmanlar olması gerekmektedir. “Adli Ebelik”, “Forensic Midwife” anahtar kelimeleri ile Pubmed, Scopus, Medline, Science Direct, Google Scholar veri tabanları taranarak erişim sağlanan makaleler değerlendirilmiştir. Çalışmanın kapsamını 27 araştırma makalesi oluşturdu. Bu makalelerin değerlendirilmesine göre hastanelerin özellikle acil servislerine, %31 oranında adli ya da adli olabilecek birçok vaka ve en çok da cinsel saldırı vakaları başvurmaktadır. Bu derlemenin amacı, ebelikte yeni bir alan olan Adli Ebelik hakkında alan yazın paylaşımı yapmaktır.
Anne Dostu Bir Hastanede Dünya Sağlık Örgütünün Pozitif Doğum Deneyimi İçin İntrapartum Bakım Önerilerinin Uygulanma Durumu: Tanımlayıcı Araştırma
Authors: IRMAK Azize , ÇOBAN Ayden
Published: December 2023

Amaç: Bu araştırma anne dostu bir hastanede Dünya Sağlık Örgütünün pozitif doğum deneyimi için intrapartum bakım önerilerinin uygulanma durumunu değerlendirmek amacıyla yapıldı.

Gereç ve Yöntem: Araştırma, basit tanımlayıcı türde, Mart 2021-Eylül 2021 tarihleri arasında, İzmir İl Sağlık Müdürlüğüne bağlı Sağlık Bilimleri Üniversitesi Tepecik Eğitim Araştırma Hastanesi Ahmet Ersan Kadın Hastalıkları ve Doğum Kliniğinde vajinal doğum yapan 384 kadın ile yürütüldü. Veriler araştırmacılar tarafından ilgili literatür taranarak hazırlanan ‘Tanıtıcı Bilgi Formu’ ve “Pozitif Doğum Deneyimi İçin İntrapartum Bakım Önerileri Formu” ile yüz yüze görüşme yöntemi ile toplandı. Araştırma verileri Statistical Package For Social Science (SPSS) 20.0 paket programı ile analiz edildi. Verilerin değerlendirilmesinde tanımlayıcı istatistikler kullanıldı.

Bulgular: Kadınların yaş ortalaması 25.825.30, %62,8’i çalışmıyor, eşlerinin %27.9’unun okuryazar olduğu ve %67.7’sinin gelirin giderine denk algıladığı, %83.2’sinin sosyal güvencesinin olduğu saptandı. Kadınların %99.4’üne travay ve doğum süresince sağlık profesyonelleri tarafından mahremiyete özen gösterilip sürekli destek sağlandığı, %40.9’una doğumun birinci evresinde perine traşı, %40.9’una lavman, %30.2’sine amniyotomi ve %79.9’une oksitosin, %99.0’ına sürekli elektronik fetal monitörüzasyon uygulandığı tespit edildi. Kadınların %59.1’ine doğumda sıvı veya yiyecek kısıtlaması ve %99,8’ine epizyotomi ve %99.7’sine doğum sonrasında uterus masajı uygulandığı saptandı.

Sonuç: Bu araştırmanın sonucunda, sağlık profesyonellerinin dünya sağlık örgütünün pozitif doğum deneyimi için intrapartum bakım önerilerinin bir kısmını uygulamadıkları sonucuna ulaşılmıştır. Bu sonuçlar kadınların pozitif doğum deneyimi edinmeleri bakımından oldukça önemlidir.
A review of little-known medicinal plant Premna herbacea
Authors: Kumar Vishavjit
Published: December 2023

Premna herbacea Roxb. (family- Lamiaceae) is well documented for its therapeutic potential in Ayurveda, Siddha, and Unani system of medicine. The species has been identified as a pyro herb based on its gross morphological features and fire regulated ecology as its likely survival strategy in habitats that experience repeated fires. The available knowledge on its ecology, phytochemical profile and pharmacological properties, which is limited in nature, was critically reviewed to provide evidence and justification to its ethno-medicinal claims and research prospects respectively.
Analisis Standar Proses Pendidikan Menuju Pendidikan Yang Berkualitas
Authors: Narwi Subandi
Published: December 2023

Proses pembelajaran menjadi efektif apabila dibarengi dengan adanya sistem yang medukung untuk kemajuan pendidikan. Penelitian ini menggunakan metode studi kepustakaan yang mengandalkan sumber bibliografi dari buku dan artikel di jurnal ilmiah yang berkaitan dengan pokok permasalahan. Hasil penelitian ini menunjukkan bahwa: 1) Standar proses pendidikan adalah standard nasional pendidikan, yang berarti standar proses pendidikan yag dimaksud berlaku untuk setiap lembaga pendidikan formal pada jenjang pendidikan tertentu dimanapun pendidikan lembaga itu berada secara nasional. 2) Standar proses berkaitan dengan pelaksanaan pembelajaran, yang berarti dalam standar proses pendidikan berisi tentang bagaimana seharusnya pembelajaran berlangsung. 3) Standar proses pendidikan diarahkan untuk mencapai standard kompetensi lulusan. Dengan demikian, standard kompetensi lulusan merupakan sumber atau rujukan utama dalam menentukan standar proses pendidikan. Kata Kunci: Standar Proses, Mutu, Pembelajaran. standar proses adalah kriteria mengenai pelaksanaan pembelajaran pada satu satuan pendidikan untuk mencapai Standar Kompetensi Lulusan. Proses pembelajaran pada Kurikulum 2013 dikembangkan menjadi dua yaitu proses pembelajaran langsung dan proses pembelajaran tidak langsung. Pembelajaran langsung berkenaan dengan pembelajaran yang menyangkut Kompetensi Dasar dari KI-3 dan KI-4 sedangkan pembelajaran tidak langsung berkenaan dengan pembelajaran yang menyangkut KD dari KI-1 dan KI-2. Keempat KI tersebut terintegrasi kedalam pendekatan saintifik.Proses pembelajaran dengan pendekatan saintifik dalam Permendikbud tentang Implementasi Kurikulum 2013 terdiri atas lima pengalaman belajar yaitu mengamati, menanya, mengumpulkan informasi, mengasosiasi, dan mengkomunikasikan. Pembelajaran IPA di tingkat SMP dilaksanakan dengan berbasis keterpaduan, pelaksanaan proses pembelajaran dengan pendekatan saintifik, menjadi langkah awal yang dilakukan oleh Badan Pengembangan Sumber Daya Manusia Pendidikan dan Kebudayaan dan Penjaminan Mutu Pendidikan, Kementerian Pendidikan dan Kebudayaan melakukan pendidikan dan Pelatihan (Diklat) Implementasi Kurikulum 2013 kepada para guru dan kepala sekolah.
Perilaku Kedisiplinan Guru Dilihat dari Etika Mengajar di dalam kelas di Pondok Pesantren Terpadu Al Multazam
Authors: Rizky Amalia Lola , Gumiandari Septi
Published: December 2023

Penelitian ini membahas perilaku kedisiplinan guru di Pondok Pesantren Terpadu Al Multazam dan bagaimana perilaku tersebut terkait dengan penerapan etika mengajar. Etika mengajar merupakan landasan moral dan normatif yang membimbing guru dalam menjalankan tugas mengajar dengan integritas dan profesionalisme serta dalam berinteraksi dengan siswa secara hormat dan kesantunan. Dalam pendekatan kualitatif dengan metode studi kasus instrumental tunggal, penelitian ini menggunakan wawancara mendalam dan observasi partisipatif sebagai instrumen utama. Hasil penelitian menunjukkan bahwa perilaku kedisiplinan guru di pondok pesantren melibatkan dimensi praktis dan teoretis yang saling terkait. Aspek praktis mencakup kemampuan menjaga ketertiban kelas, menerapkan aturan pesantren, dan konsistensi dalam menjalankan tugas mengajar. Dari perspektif teoretis, etika mengajar memainkan peran sentral dalam membentuk perilaku kedisiplinan guru dengan mengintegrasikan nilai-nilai agama, moral, dan budaya pesantren. Hubungan antara etika mengajar dan pembentukan karakter siswa juga ditemukan, di mana etika mengajar membantu membentuk karakter siswa sesuai dengan nilai-nilai pesantren. Meskipun demikian, tantangan dalam menerapkan etika mengajar dan menjaga kedisiplinan dihadapi, termasuk variasi latar belakang siswa dan dilema etika dalam pengambilan keputusan pembelajaran. Penelitian ini menggarisbawahi pentingnya penerapan etika mengajar dalam membentuk perilaku kedisiplinan guru dan menciptakan lingkungan belajar yang kondusif serta membina karakter siswa sesuai dengan nilai-nilai pesantren.
Criminalistic aspects of the organization of preparation and submission of requests for legal assistance in criminal cases on crimes with the participation of foreign citizens
Authors: Беспамятнов Р.В.
Published: December 2023

В статье анализируются криминалистические особенности подготовки и направления запросов об оказании взаимной правовой помощи по уголовным делам о преступлениях, совершенных иностранными гражданами или в отношении них, в частности делается акцент на планировании такой деятельности, вследствие чего делаются соответствующие выводы.

The article analyzes the forensic features of preparing and sending requests for mutual legal assistance in criminal cases on crimes committed by or against foreign citizens, in particular, the emphasis is on planning such activities, as a result, the author draws appropriate conclusions.
Research analysis of data-driven submarine navigation adaptation zones based on factor analysis
Authors: Chen Qiaojun , Guang Jiahe , Zhang Lixing , Zhang Yiyang , Liu Sitong
Published: December 2023

The study of gravity anomaly adaptation zones holds significant importance in resource exploration, environmental studies, and marine development. This paper initially collected and preprocessed data on gravity anomalies, dividing them into 16 sub-regions. Subsequently, five statistical parameters of gravity field characteristicsstandard deviation, roughness, gradient, gravity entropy, and planar correlationwere introduced, and factor analysis was employed to compute scores for each area. Finally, MATLAB software was utilized to construct a three-dimensional distribution map of gravity anomaly values. The results indicate that factor analysis demonstrates promising applications in the research of data-driven submarine navigation adaptation zones.
Структура магнитного поля звезды HD133880 (si)
Authors: Глаголевский Ю. В.
Published: December 2023

Проведено моделирование магнитного поля звезды HD133880 при предположении структуры магнитного поля описываемого двумя теоретическими магнитными диполями. Сравнение результата с тем, что получалось ранее при использовании представления фазовой зависимости Be() путем дипольно + квадрупольно + октупольного расширения структуры показывает, что эта схема приводит только к формальному описанию фазовой зависимости, а члены разложения не несут физического смысла.The magnetic field of the star HD133880 is modeled under the assumption of
the structure of the magnetic field in the form of a theoretical magnetic dipole.
Comparison of the result with what was obtained earlier when using the representation
of the phase dependence of Be() by dipole+quadrupole +octupole expansion of
the structures shows that this scheme leads only to a formal description of the phase
dependence, and the expansion coefficients do not have physical meaning.
Периодичность частоты вспышек активных вспыхивающих звезд обнаруженных tess
Authors: Акопян А. А.
Published: December 2023

Поступила 8 ноября 2023 По данным орбитальной обсерватории TESS проведено исследование наиболее активных вспыхивающих звезд, показавших по 100 и более вспышек за период с июля 2018 по октябрь 2020гг. Основными направлениями исследования были: а) анализ кривых блеска, определение периодов осевых вращений, выявление физических особенностей у отдельных звезд, б) определение параметров периодической/циклической переменности частоты вспышек вспыхивающих звезд, обусловленной осевыми/орбитальными вращениями. Были получены соответствующие периоды функции частоты вспышек и проведено сравнение с периодами вращения звезд. Периоды функций частоты вспышек оказались близкими к периодам осевых вращений звезд. Построены теоретические распределения вспышек по фазам, которые сравнены с аналогичным наблюдаемым распределением вспышек при данном периоде. Для всех без исключения звезд сравнение с помощью критерия 2 свидетельствует в пользу периодичности частоты вспышек. Предположено, что распределение пятен по долготе вспыхивающих звезд можно представить угловым распределением фон Мизеса, параметры которой определяются через соответствующие параметры функции частоты вспышек. Подробно обсуждена двойственность звезды CD-56 1032.
TESS data was used to study active flare stars, finding 100 or more flares between July 2018 and October 2020. The main objectives of this study were analyzing light curves, determining axial rotation periods, and identifying the physical features of flare stars. The corresponding periodic functions of the flare frequency are derived and checked for possible periodicity matching the star's rotation period. The flare frequency functions correlated closely with the stars' axial rotation periods. Theoretical phase distributions of flares are constructed and compared with a similar observed distribution of flares for a given period. For all stars without exception, this comparison (using the 2 criterion) argues in favour of the periodicity of the flare frequency. It is assumed that the distribution of spots along the longitude of flare stars can be represented using by the von Mises angular distribution, the parameters of which are determined through the corresponding parameters of the flash frequency function. The binarity of the star CD-561032 is discussed in detail.
Antibacterial activity of S, N- disubstituted quinazolines
Authors: Hovasyan Z. A. , Poghosyan S. H. , Hakobyan M. R. , Stepanyan H. M. , Muradyan R. E. , Harutyunyan A. A.
Published: December 2023

Melting points, IR spectral data, and results of studying the antibacterial activity of new synthesized 2,3-disubstituted quinazolin-4(3H)-ones are presented. The antibacterial properties of quinazolines were studied against four strains of gram-positive and gram-negative bacteria.
Ներկայացված են հալման կետերը, IR սպեկտրային տվյալները և նոր սինթեզված 2,3-դիփոխարինված քինազոլին-4(3H)-երի հակաբակտերիալ ակտիվության ուսումնասիրության արդյունքները: Ուսումնասիրվել են քինազոլինների հակաբակտերիալ հատկությունները գրամ դրական և գրամ-բացասական բակտերիաների չորս շտամների նկատմամբ:
Приведены точки плавления, данные ИК-спектров и результаты изучения антибактериальной активности новых синтезированных 2,3-дизамещенных хиназолин -4(3H)-онов. Изучены антибактериальные свойства хиназолин.
МАО-ингибирующая активность новых производных аминотиенопиримидинов и родственных соединений
Authors: Григорян А. С.
Published: December 2023

Исследовано влияние новых производных из ряда аминотиенопиримидинов и родственных соединений на активность моноаминоксидазы (МАО) мозговой ткани крыс в условиях in vitro. В качестве субстрата использован серотонин (5-ОТ) креатинин сульфат. Исследования показали, что только производное этилового эфира тиофен-3-карбоновой кислоты проявило умеренную анти МАО-активнсть, в то время как остальные соединения оказались малоактивными.
Ուսումնասիրվել է մի քանի նոր տեղակալված ամինոտիենոպիրիմիդինային շարքի միացությունների ակտիվությունը մոնոամինօքսիդազա ֆերմենտի նկատմամբ առնետի ուղեղում In vitro պայմաններում: Որպես սուբստրատ կիրառվել է սերոտոնին(5-ОТ) կրեատինին սուլֆատը: Հետազոտությունները ցույց տվեցին, որ այս շարքի էթիլ 2-(-3-բենզոիլթիոուրեիդո) -6ֆենիլ -6 – ցիանո -4,5,6,7-տետրահիդրո բենզո[բ]տիոֆեն-3-կարբոքսիլատ միացությունները ցուցաբերում են զգալի հակա ՄԱՕ ակտիվություն, իսկ որոշ միացություններ ունեն թույլ ակտիվություն:
The effect of some new substituted aminotienopirimidines on activity of monoamine oxidaze (MAO) in rat brein was studied in vitro. Serotonin (5-OT) kreatininsulfate used as a substrate in grupetil 2-(-3-benzoltioureido)-6-fenil-6-ciano-4,5,6,7 tetrahydrobenzob]tiofen-3-karboxilat. It was found, that some preparatis derivative exibit a moderate antiMAO action, while the other studied compounds were inactive
Ճագարների էյմերիոզի դեմ պայքարի միջոցները
Authors: Բարսեղյան Ռ. Է.
Published: December 2023

Էյմերիոզի նկատմամբ կանխարգելիչ միջոցառումների փորձարկումները կատարվել են արհեստականորեն վարակված 1-3-ամսական կալիֆորնիական և հսկա ցեղի, ինչպես նաև խառնացեղ ճագարների վրա: Կանխարգելման նպատակով բարելավվել է կերակրման և խնամքի պայմանները: 10-օրյա հետազոտության արդյունքները ցույց են տվել, որ ճագարներին «ՄՈԴՈՒՍ ԳՐԱՆՈՒՄ» ՍՊԸ գրանուլներով կերակրման և խնամքի ճիշտ կազմակերպման դեպքում էյմերիաների` օօցիստներով պայմանավորված վարակվածության ինտենսիվությունը նվազում է, իսկ յոդի 0.01% լուծույթի օգտագործումը տալիս է թերապևտիկ արդյունք:
Опыты по проведению противоэймериозных мероприятий осуществлялись на 1-3-месячных крольчатах калифорнийской породы, породы великан, а также на помесных кроликах. С целью повышения эффективности мероприятий были созданы надлежащие условия кормления, ухода и содержания крольчат. Длительность опытов составляла 10 дней. Результаты исследований показали, что кормовые гранулы "MODUS GRANUM", а также необходимый уход и содержание приводят к снижению интенсивности инвазии эймериями, а применение 0,01%-го раствора йода дает положительный терапевтический эффект.
Experiments on the implementation of anti-Emeriosis measures were carried out on 1-3-month-old rabbits of the Californian and giant breeds, as well as crossbred rabbits. In order to increase the effectiveness of the activities, proper conditions for the rabbit feeding, care, and housing were created. The experiment duration was 10 days. The research results showed that "MODUS GRANUM" granules, as well as the necessary care and keeping lead to a decrease of the intensity of Eimeria invasion, and the use of 0.01% iodine solution gives a positive therapeutic effect.