bluuebunny/crossref_metadata_2025 huggingface dataset:
Los proyectos de aula como estrategia didáctica en el proceso educativo en la educación superior
Authors: Guerrero-Jirón Juan Ramiro , López-Feijoo Manuel Arcesio , Galarza-Mora Wilmer Gonzalo
Published: August 2023

En el presente estudio de investigación  pretende analizar los proyectos de aula como estrategia didáctica en el proceso educativo en la educación superior, destacando a los proyectos  disciplinarios, interdisciplinarios, transdisciplinarios en círculos de estudio  en el proceso enseñanza  aprendizaje, tales proyectos posibilitan la vinculación entre los contenidos, metodologías activas, aprendizaje basado en problemas, estudio de casos, entre otros, y la oportuna combinación entre teoría y práctica, es decir se plasma la praxis educativa. En este apartado, se destaca a la fusión entre el uso de proyectos y didáctica, como parte de la interacción dinámica en el aula.  La metodología de investigación es descriptiva bibliográfica y de campo, el problema central es el desconocimiento en la elaboración de los proyectos de aula.  El objetivo es analizar las fases e importancia de la aplicación de los proyectos de aula, como un instrumento de planificación en el currículo. La importancia de los proyectos de aula en la planificación docente es articular los componentes pedagógicos, tales como: objeto, objetivo, problema, contenidos, formas de enseñanza, métodos, técnicas, recursos, estrategias y la evaluación como un proceso sistémico y holístico en el proceso educativo.  Por tal razón el docente asume un rol fundamental en calidad de mediador para consolidar destrezas, competencias a base de las habilidades, conocimientos y capacidades de los estudiantes, que permite alcanzar desempeños, productos y demostraciones en los estudiantes, asumiendo el papel de protagonista en la construcción de su propio conocimiento de saberes, los cuales responden a la solución de problemas del contexto, a través de proyectos.
Abordaje diagnóstico y tratamiento del síndrome de Rendu-Osler-Weber
Authors: Ruiz-Procel Fabricio Josue , Puente-Mosquera Karola Adriana
Published: August 2023

El síndrome de Rendu-Osler-Weber, también conocido como telangiectasia hemorrágica hereditaria, es una enfermedad genética de predominio hereditario autosómico dominante que se caracteriza por la presencia de malformaciones arteriovenosas y lesiones telangiectasicas especialmente en la piel, mucosas, tracto digestivo y sistema respiratorio. El objetivo del presente estudio es describir el abordaje diagnóstico y tratamiento. Estas malformaciones pueden provocar episodios recurrentes de sangrado llevando a complicaciones, como anemia e insuficiencia cardiaca. Su prevalencia es aproximadamente 1 de cada 5,000 personas en todo el mundo. Sin embargo, debido a la naturaleza subdiagnosticada de la enfermedad, es posible que este número subestime su verdadera prevalencia. Es crucial determinar las opciones terapéuticas más efectivas y seguras para el manejo de este síndrome. Incluyendo medidas farmacológicas, intervenciones quirúrgicas y terapias de radiología intervencionista. La presencia de malformaciones arteriovenosas puede causar accidentes cerebrovasculares o hemorragias, lo que demuestra su relevancia. El diagnóstico temprano y adecuado es crucial y es importante crear conciencia en la comunidad médica y educar a los profesionales de la salud, para facilitar su detección y diagnóstico. La investigación de terapias futuras y el asesoramiento genético, ayudaría a identificar biomarcadores, dianas específicas de tratamiento y enfoques terapéuticos innovadores que puedan mejorar su salud y calidad de vida.
A OUVIDORIA COMO INSTRUMENTO DE GOVERNANÇA PÚBLICA
Authors: Josino Josivan Rocha , Fonteles José Célio Pessoa , Pordeus Marcel Pereira
Published: August 2023

O presente artigo visa a discutir o papel da ouvidoria como instrumento auxiliar dos controles internos e da gestão de risco, mecanismo essencial para a execução de uma boa governança pública. Questão fundamental debatida é a autonomia que a ouvidoria deve manter em suas ações, em especial no momento da escolha do ouvidor. O escolhido pode fazer parte dos quadros  da instituição, porém não deve ter vínculo funcional ou administrativo com autoridades que serão avaliadas pelo serviço de ouvidoria, primando pela transparência e independência em suas análises das reclamações, críticas e sugestões feitas pelo cidadão. Outra condição importante para o adequado funcionamento da ouvidoria é a existência de controle externo à atividade, que a acompanha, controla e define novos rumos para os trabalhos.
PREVENÇÃO DO SUICÍDIO: SINAIS DE ALERTA E DIRECIONAMENTO ADEQUADO DOS PACIENTES
Authors: De Almeida Vivaldo Gemaque , Nascimento Junior Jorge Carlos Menezes , Cardoso Pablício Pereira
Published: August 2023

O suicídio representa um grave problema de saúde pública em âmbito global, constituindo uma das principais causas de morte prematura, especialmente entre jovens. Considerando também as tentativas não fatais, fica evidente a necessidade de estratégias abrangentes de prevenção, enfocando os fatores de risco e o manejo adequado de indivíduos em risco. O presente estudo teve por objetivo explorar as principais estratégias para a prevenção do suicídio mediante revisão integrativa da literatura científica recente sobre o tema. Buscou-se identificar os principais fatores de risco e proteção contra o suicídio em distintas populações, bem como abordagens efetivas de prevenção baseadas em evidências nos níveis individual, clínico e populacional. Conclui-se que a prevenção efetiva do suicídio exige uma abordagem multinível, envolvendo a identificação e manejo precoces de indivíduos em risco, assim como a implementação de estratégias em nível populacional para redução dos fatores sociais, culturais e econômicos precipitantes. A integração coordenada de intervenções nos níveis clínico, social e político-público mostra-se crucial para uma prevenção abrangente e efetiva do suicídio.
Molecular typing of Brucella species by PCR-RFLP and SSCP
Authors: HEMADE M V , GANDGE R S
Published: August 2023

PCR-RFLP and PCR-SSCP help to understand variabilities in Brucella spp. genome which in turn assist in planning epidemiological strategies for control of brucellosis in animal population and thereby human transmission. Restriction fragment length polymorphism (RFLP) analysis was carried out for BCSP31 (223 bp) gene of 15 isolates using restriction enzyme HaeII and BsaBI. All isolates yielded a similar restriction pattern as that of reference strains i.e. 189 + 34 bp and 164 + 60 bp fragments with HaeII and BsaBI restriction enzyme, respectively. PCR- SSCP analysis of BCSP 31 gene of 33 Brucella spp. isolates was carried out. Seven different SSCP band patterns designated from “A” to “F” were observed. Out of 33 isolates of Brucella spp., 19 isolates showed SSCP profile similar to ATCC reference strains of Brucella spp. designated as band pattern “A” indicating no polymorphism. Whereas, 14 isolates showed polymorphism in SSCP band pattern designated from “B” to “G”. Band pattern “A” was the most common in 19 (57.58 %) isolates followed by “B” in 6 (18.18 %) isolates and “G” in 4 (12.12 %) isolates, whereas “C”,”D”,”E”, and “F” band patterns were found in each of 1 (3.03 %) isolate. SSCP band pattern “A” was observed most commonly in buffalo (10) followed by human (6) and cattle (3). The SSCP band pattern “B” was found in equal proportion in cattle and buffalo (3 each). The “C” and “E” SSCP band patterns were observed in cattle, whereas “D” and “F” SSCP band pattern was noticed in buffalo and human isolates, respectively. The “G” SSCP band pattern was observed in 3 cattle and 1 goat isolate. In cattle-ABCEG, buffalo-ABD, goat-G and in human-AF band patterns were seen. Comparative results of RFLP and SSCP in 15 isolates showed that, PCR-SSCP is more sensitive than RFLP for detection of polymorphism in BCSP31 gene.
Molecular characterization of Listeria monocytogenes in bovine milk and evaluating the sensitivity of PCR for direct detection in milk
Authors: LAXIMAN SAWANT , KAUR SIMRANPREET , AULAKH R S , GILL J P S
Published: August 2023

Food-borne listeriosis, recognized as an emerging bacterial disease of humans and animals worldwide, is caused by L. monocytogenes with at least 95% of the strains isolated from foods and patients belonging to serovars 1/2a, 1/ 2b and 4b. Milk and dairy products were implicated as sources of listeriae in several widely publicized incidents, thus suggesting that the mammary glands of mastitic cattle may be an important reservoir of Listeria. In the present study, 350 bovine milk samples were collected for prevalence and molecular characterization studies of Listeria spp. The isolates were phenotypically and genotypically characterized by biochemical tests, haemolysis on sheep blood agar, CAMP test, PI-PLC assay and multiplex PCR targeting virulence cluster genes namely haemolysin (hlyA), PI-PLC (plcA), actin (actA), p60 (iap) and regulatory (prfA); along with multiplex PCR for typing major serovars targeting lmo0737, ORF2819, ORF2110 and prs genes. Four pathogenic L. monocytogenes were recovered indicating prevalence rate of 1.14% in milk while the overall prevalence rate of Listeria spp. was 1.42%. All the four pathogenic isolates were characterized as L. monocytogenes serotype 4b. Antibiogram of the pathogenic L. monocytogenes isolates revealed sensitivity for amikacin, gentamycin, norfloxacin and doxycyclin. Animal sera (169) screened by indirect ELISA for antibodies against listeriolysin O showed sero-positivity of 7.1%. Sensitivity of PCR for direct detection from milk was evaluated to be 8.8 × 105 L. monocytogenes cells/ml of milk. Thus, the presence of pathogenic strains of L. monocytogenes in raw milk appeared to be a cause for concern with profound public health implications.
Detection of species-specific genetic markers in goat, sheep and pig by molecular characterization of Cytochrome b gene
Authors: RAJKHOWA DEEKSHITA , KALITA D J , BORAH P , HUSSAIN MD I , SAIKIA D P , FERDOCI A M
Published: August 2023

Present work was designed to know the inter-species genetic variation by detecting polymorphisms and analysing the nucleotide sequences of cytochrome b gene. Blood samples were collected from apparently healthy adult animals of indigenous goat, sheep and pig of Asom, and mitochondrial DNA was extracted for amplification by PCR. One half of the PCR product was used for restriction digestion while the other half after purification was sent for sequencing. Species specific restriction patterns were observed for cytochrome b gene amplicon upon digestion with AluI, HinfI, and HaeIII. The nucleotide sequence results were further analyzed using ClustalW and Mega5 softwares for unambiguous species typing. The percent similarity study showed that goat cytochrome b gene had 89.64 and 82.12% similarity with sheep and pig respectively. Phylogenetic tree also revealed close relationship of goat and sheep cytochrome b gene. Lowest pair wise distance was observed between goat and sheep (0.123) followed by goat and pig (0.227). Pig and sheep cytochrome b gene showed the highest degree of pair wise distance (0.255) between the nucleotides. From the present study, it can be concluded that RFLP and sequence analysis of cytochrome b gene provided the information about the extent of inter-species genetic diversity and can be used as a powerful tool for genetic traceability of species.
Superovulatory responsiveness and embryonic development in Iranian Afshari ewes treated with two different concentrations of bovine somatotropin
Authors: SAFDAR AMIR HOSSEIN ASGARI
Published: August 2023

Bovine somatotropin (bST) was administered @ 50 and 100 mg at the beginning of the estrus synchronization and natural mating of the sheep to evaluate the improvement of the ovulation rate, embryonic development and pregnancy rate of the transferred embryos. Donors (48) were treated with 3 different types of treatment; group A (15): treated with bST-100, received 100 mg of bST at the beginning of the synchronization and natural mating, group B (15): treated with 50 mg of bST same as the previous group and control (18) did not receive any type of bST. Each recipient (108) received 2 embryos: 30 recipients received embryos from bST-100s, 45 received the embryos from bST-50 and 33 received embryos from the control group. Using SAS related GENMOD method, superovulatory response, embryo recovery, cleavage rate, transferable embryo percentage, quality of embryos, rates of pregnancy and embryonic development were analyzed. Using GLM procedure, numbers of corpus luteum and blastocyst cells were analyzed. The results showed that bST administration had no significant effect on superovulatory response, number of CL and recovered structures. Number of transferable embryos and embryos that had reached to the blastocyst in bST-50 was more than bST-100 and control group. In conclusion, treatment 50 mg bovine somatotropins enhance the ratio and growth of the transferable embryos. Embryos of bST-50 treatment indicated an improved embryonic development but bST did not affect the pregnancy rates of transferred embryos.
Chemical composition, in-vitro fermentation and methane production potential of unconventional feed resources in goats
Authors: TRIPATHI M K , MEENA RAMKESH , RAHAL ANU , TRIPATHI PRABHAT , KUMAR RAVINDRA , CHAUDHARY U B , GUPTA D L
Published: August 2023

Unconventional feed resources namely Aloe barbadensis (ALB), Musa paradisiaca (MUP), Punica granatum (PUG), Murraya koenigii (MUK), Lawsonia inermis (LOI) and Boehravia diffusa (BOD) were assessed for in- vitro methane production potential and fermentation with whole goat rumen flora. Nutrient content of all the bio- resources were different, and the gas production varied from 57.7 to 161.7 ml/ g DM, with the highest gas in ALB and the lowest in BOD. Although, gas production was different among all feed resources, however gas production for each gram DM fermented was similar in MUP, PUG, MUK and LOI leaves. Methane production ranged from 6.7 to 18.9 g and 10.5 to 22.83 g/ kg DM and g/ kg fermented DM respectively. The energy loss in the form of methane also followed the trend of gas production, which ranged from 11.4 to 17.1% of digestible energy. Therefore, feed resources with varying nutrient contents have significant variations in fermentability and methane production potential.
TransJakarta Service Evaluation in Controlling COVID-19 Transmission Using Twitter Sentiment Analysis
Authors: Nurlaela Siti , William Andrew
Published: August 2023

This study attempted to understand passenger perception of using public transport by utilizing Twitter data about the services of the TransJakarta Busway. Tweets were the main data source to capture users’ responses toward these services. Users’ perceptions were analyzed by sentiment analysis using a naïve Bayes algorithm. Furthermore, content analysis was used to inform improvements in service maintenance. The findings showed that the pandemic had a major impact on TransJakarta services, from a decrease in users, route closures, and fleet reductions to changes in user behavior. Most Tweets were negative regarding (1) poor bus frequency, leading to long queues and passenger overcrowding at bus stops and inside buses; (2) failure to maintain social distancing measures; (3) frequent violations of the 50% bus capacity reduction during peak hours, and showing a lack of consideration in measuring demand size during peak hours; (4) staff’s weak control of implementing the health protocol exacerbated poor services. This study suggests service improvement based on peak hour demand analysis to offset the implications of a 50% capacity restriction by providing proper bus frequencies and headway arrangements considerable enough to avoid crowding, followed by optimal monitoring of health protocol by staff. Tweet data may inform poor management in controlling the transmission of COVID-19 on public transportation. Hence, using Twitter data could replace conventional data collection methods like user interviews. Beneficial information from Tweet data can be captured at relatively low costs. Therefore, it may aid the evaluation of PPKM policy implementation to create more resilient public transportation during pandemics.
Menelisik Dampak Estetika dalam Pemberitaan Firman terhadap Spiritualitas Jemaat di Era Post Truth
Authors: Elvrita Natalia , Hastuti Ruwi
Published: August 2023

Abstract: Preaching the Word should accommodate three main areas, namely truth, goodness, and beauty. This study aims to explain empirically the influence of the aesthetic dimension in preaching the word to the congregation of the Central Kalimantan I Assemblies of God Church in the post truth era. The method used in this study is a quantitative method with a questionnaire approach and literature review. This article discusses Christian spirituality, preaching the word in the post truth era and the impact of the aesthetic dimension in preaching the word on Christian spirituality, specifically in relation to God, oneself, others and nature. Based on the results of the research in this article, it was found that the high aesthetic dimension in preaching the word in the post truth era resulted in low congregational spirituality. The congregation does not experience spiritual growth when the word delivered is based on the subjectivity of the preacher of the word
Abstrak: Pemberitaan Firman seharusnya mengakomodir tiga area utama yaitu kebenaran, kebaikan, dan keindahan. Penelitian ini bertujuan untuk menjelaskan secara empiris mengenai pengaruh dimensi estetika dalam pemberitaan firman terhadap jemaat Gereja Sidang Jemaat Allah Kalimantan Tengah I di era post truth. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan pendekatan kuesioner dan kajian literatur. Artikel ini membahas tentang spiritualitas Kristiani, pemberitaan Firman di era post truth dan dampak yang ditimbulkan dari dimensi estetik dalam pemberitaan firman terhadap spiritualitas Kristiani, secara khusus dalam hubungannya dengan Tuhan, diri sendiri, orang lain dan alam. Berdasarkan hasil penelitian dalam artikel ini ditemukan bahwa tingginya dimensi estetik dalam pemberitaan firman di era post truth menghasilkan spiritualitas jemaat yang rendah. Jemaat tidak mengalami pertumbuhan secara spiritual ketika firman yang disampaikan bersumber pada subyektivitas dari pemberita firman tersebut.
Macroeconomic Variables and the Returns on Stock Prices: Empirical Evidence from Nigeria
Authors: Odey Ferdinand Ite , Oko Innocent Odey
Published: August 2023

In spite of the vital roles performed by the stock exchange market for the overall national development, it is still performing below expectations in Nigeria owing to several macroeconomic factors. Accordingly, the main objective of this study is to investigate the effects of selected macroeconomic variables on returns of stock prices in Nigeria. The study employed time series data obtained from the Central Bank of Nigeria statistical bulletin and World Development Indicators. Returns of stock price was measured using all-share index while the identified macroeconomic variables include GDP growth, broad money supply, exchange rate, interest rate and inflation rate. Autoregressive Distributive Lag (ARDL) estimation technique was used to establish the long run relationship among the variables and it was revealed that long run relationship exists among the variables in the estimated model. The result of the Error Correction Mechanism (ECM) within the framework of the ARDL shows that macroeconomic variables such as gross domestic product, broad money supply, exchange rate and interest rate have positive effect on returns of stock prices in Nigeria. On the other hand, the results showed that inflation rate has negative effect on stock prices in Nigeria. Predicated on the result, the study recommended that policies to increase gross domestic product, exchange rate, interest rate and money supply should be implemented because they can lead to improvement in the returns of stock prices, while inflation rate should be maintained at single digit to prevent its negative effect on the performance of the stock market in Nigeria.
Critical Discussion on Basic Factors of Marketing Management in Organizations and Responses to Environmentally Concerned Market
Authors: Ladan Mohammed Musa , Mohammed Yahaya Isa
Published: August 2023

A business enterprise marketing strategy of Listening, Understanding, and Adapting to a particular place confirmed its dynamic strategy in business operations. When an enterprise has customer-centric, region-centric and ethno-centric marketing strategies in its enterprising, it is easy to enter marketplace, particularly with huge population, with different ethnics groups and great market potential, with its most product designing fit well in every market, in terms of global markets or customers. Thus, this paper examined the need to manipulate marketing mix, to meet local consumer needs to fit business operations in different part of the world. The paper employed the use of related literature in building the discussion. The paper observed that; product, price, promotion, place, packaging, positioning and patronage, can greatly put an enterprise on track to achieve maximum market share in marketplaces. In addition, an organization may face big challenge in area of environmental influences, in using technology to promote its products, web sides, like email, and you tube, in a place like Nigeria, due to poor nature of electricity. If an enterprise chooses to operates from distant place, using social networking site to link to its consumers. Thus, an enterprise should have compliance policy and tolerance and patience when it comes to environmental issues that can help it to achieve great success in a place.
Evaluation of the Effect of Financial Performance on Dividend Payout of Deposit Money Banks in Nigeria
Authors: Chikwute Ubesie Madubuko Cyril Odume Magnus Sunday Nwachukwu Raphael
Published: August 2023

This study evaluates the effects of financial performance measures on the dividend payout of deposit money banks in Nigeria The specific objectives are to determine the effect of earnings per share on dividend per share of deposit money banks in Nigeria, to examine the effect of return on assets on the dividend per share of deposit money banks in Nigeria, to assess the effect of return on equity on dividend per share of deposit money banks in Nigeria and to evaluate the effect of profit for the year on dividend per share of deposit money bank in Nigeria from 2011 to 2020. The proxies for the independent variables, Financial performance, are earnings per share, return on assets, return on equity and profit for the year while the proxy for dividend payout is dividend per. The study adopted ex post factor research design. Secondary data were obtained from the annual audited reports of the banks from 2011 to 2020. Correlation coefficient was used to determine the strength of association among the variables while multiple regression analysis was used to analyze the data obtained. The finding of the study revealed that earnings per share and return on assets had significant positive effects on dividend per share; return on equity had insignificant positive effect on dividend per share while profit for the year had significant negative effect on dividend per share of deposit money banks in Nigeria. The researcher concluded that financial performance measures had significant positive effect on dividend per share except for profit for the year that had negative and significant effect on dividend per share of deposit money banks in Nigeria. It was recommended among others that Management should improve on their Earnings Per Share (EPS), Return on Assets (ROA) and Return on Equity (ROE) as they are of importance in determining the dividend payout of deposit money banks in Nigeria. Banks’ management to design an optimum dividend policy that will enhance per
The colonialities experienced by blacks: Reflections to break with colonial naturalizations in music training
Authors: Santos Daniel Silva dos , Peters Ana Paula
Published: August 2023

Considering the Brazilian social context between the late nineteenth and early twentieth centuries, and with the popular music of black influence as a background, the present work brings reflections on the need to break with naturalizations and discourses based on coloniality, still so present in the environments of music formation. Debating narratives that evidence the colonialities experienced by black musicians in the history of popular music can be the starting point for a decolonial action that promotes the expansion of perspectives in higher music education, especially avoiding the reproduction of colonialities.
Peripheral inflammatory neuropathy related to oral vaccine against polyomyeloitis: A case report
Authors: Santos Laura Goedel dos , Iser Betine Moehlecke , Santos Júlia Goedel dos , Fernandes Artur Furlaneto
Published: August 2023

At two years of age, 10 months after the 1st booster of the oral poliovirus vaccine, the pacient started with a subacute presentation of hypotrophy of the left lower limb, hyporeflexia and scarvating gait due to lack of function of the foot dorsiflexors. Cranioencephalic tomographic studies and lumbosacral spine MR were performed, ruling out anatomical alterations. In electroneuromyography examination, sciatic neuritis was observed. The patient's condition continued to evolve negatively, resulting in deformity of the foot structure and difficulty in walking less than one year after the onset of symptoms. It is not possible to state that the neuropathy was the exclusive result of an adverse reaction to the polio vaccine, however this is the most likely pathophysiological mechanism considering that other causes have been ruled out and the condition progresses with muscle paralysis typical of poliomyelitis. The present case report is important for epidemiological control and containment of virus damage.
Pickling as a Preservation Technique for Solanum aethiopicum; An Edible Green Leafy Vegetable
Authors: Akoth Sarah , Nuwagira Albert , Byakika Stellah , Mukisa Ivan Muzira
Published: August 2023

Solanum aethiopicum is a nutrient rich green leafy vegetable whose utilisation is limited by its short shelf life. Although refrigeration and freezing are effective methods to preserve vegetables, these methods may not be available and affordable in resource-limited settings. A viable alternative is pickling, which is a cost effective and easy to apply method. In this study, nakati leaves were fermented in brine with 3% dry salt and 2% sugar at 25°C for 14 days. The fermentation was monitored at intervals by enumerating lactic acid bacteria (LAB), coliforms and fungi as well as measuring the brine pH. Sensory evaluation (n=30) was carried out to assess the acceptability of the vegetables. Shelf stability was evaluated for three weeks. The results showed that lactic acid bacteria increased significantly (P < .001) from 2.06 log cfu/ml to 8.2 log cfu/ml during fermentation. Coliforms and fungi reduced from 5.5 log cfu/ml and 1.5 log cfu/ml to undetectable levels within 8 and 6 days of fermentation, respectively.  The brine pH decreased from 5.87 at day 0 to 3.35 after 14 days of fermentation (P < .001). Pickled nakati had lower consumer acceptability scores (P < .001) than fresh nakati. The nakati remained stable during the three weeks of storage. Therefore, pickling offers a potentially viable preservation method that can be adopted for green leafy vegetables.
Zoochemical-mediated Nanoparticle Synthesis Using Marine Sponge Hyattella intestinalis (Lamarck, 1814) as a Reducing Agents
Authors: Karnan R. , Sukumaran M. , Velavan S.
Published: August 2023

The aim of the study is to explore zoochemical-mediated nanoparticle synthesis using marine sponge Hyattella intestinalis as a reducing agents. In this term, zoochemical-mediated nanoparticle synthesis using the zoo-chemicals from zoo-extract, which contains zoo-chemicals, is involved as reducing agents. The first time authors introduced the term “zoochemical-mediated nanoparticle synthesized” using zoo-chemicals from marine sponge Hyattella intestinalis as a reducing agent, which were involved in reducing metal ions to form nanoparticle. Zoo-chemicals are naturally occurring animal secondary metabolites like alkaloids, terpenoids, etc., produced by Hyattella intestinalis marine sponges, which are equivalent to plant secondary metabolites. Marine sponge Hyattella intestinalis provided several zoo-chemicals involved in reducing copper ions into Cu2+ from Cu0, which is a response to zoochemical-mediated CuO nanoparticle synthesis as recording zoo-chemicals as reducing agents. The finding of the results, zoo-chemicals are evidence of reducing agents that use nanoparticle synthesis, which results in effective nanobased, eco-friendly drugs.  The author scientifically first time coined the term "zoochemical-mediated nanoparticle synthesis" using zoo-chemicals from Hyattella intestinalis.

Graphical abstract of zoochemical-mediated nanoparticle synthesis using marine sponge Hyattella intestinalis (Lamarck, 1814) as a reducing agents
El origen del héroe: Germán Busch y su fundamentado nacimiento en Santa Cruz
Authors: Pinto Cascán Darwin
Published: August 2023

La figura del héroe es importante en la construcción de la identidad y la historia de los pueblos, de modo que cuando se arrojan dudas sobre la vida de éste urge aclararlas para evitar que esa distorsión se convierta en verdad aceptada. Un ejemplo de esto se da durante el auge cultural y militar de la antigua Grecia, en donde los héroes eran el punto medio entre los hombres y los dioses, por lo que los hechos de sus vidas se preservaban. En ese contexto, Germán Busch Becerra (1903-1939) es considerado un héroe boliviano por su acción como soldado en la Guerra del Chaco, como gobernante del país e inspirador de la revolución nacionalista de 1952. Se trata de un factor de cohesión identitaria para la nación y su historia, razón por la cual su biografía no debe dejar lugar a confusiones. Sin embargo, en 2007 surgió una hipótesis que cuestiona su origen cruceño y apunta a uno beniano. Para dar una respuesta fundamentada a dicha controversia, esta investigación somete a ambas hipótesis de origen a contrastación -según el paradigma falsacionista- para determinar la consistencia lógica interna de cada hipótesis y definir cuál es la mejor respuesta a la pregunta sobre el lugar de nacimiento de Busch. Para ello se utilizaron 32 fuentes válidas datadas entre 1903 y 2022. El resultado arroja que la hipótesis de mayor consistencia interna es la del origen cruceño del héroe, mientras que se comprueba que la hipótesis beniana es marginal y carece de fuentes primarias. Así, la investigación concluye que Germán Busch nació en San Javier de Chiquitos (Santa Cruz) el 23 de marzo de 1903, con lo que se define el lugar de origen del mayor héroe nacional del siglo XX y el del más grande cruceño que ha vivido.
Digital storytelling en investigación e intervención: relato de experiencias en comunidades rurales en Bolivia
Authors: Guardia Crespo Marcelo , Ávila Sánchez Eduardo
Published: August 2023

El Digital Storytelling (DST) es una técnica cualitativa de investigación y de intervención formativa, que se basa en narrativas grupales audiovisuales y reflexión de sujetos en situación de vulnerabilidad. Este trabajo es un relato de experiencia (estudio de caso) de la aplicación de la presente técnica en cuatro zonas rurales de Bolivia, para conocer las percepciones de distintos jóvenes respecto a problemas que los afectan, en particular, el problema de los incendios de los bosques en la zona de la Chiquitanía. La identificación de causas y consecuencias de los mismos ha servido para identificar líneas de intervención colectiva que se orientan a la acción social.
Framing Complex Challenges
Authors: Sinfield Joseph , Kotian Romika
Published: August 2023

Innovating to achieve impact at scale in ill-structured environments is a complex challenge, with numerous socio-techno-economic dimensions. Whether tailoring a product or service offering to meet the needs of a global customer base, forecasting the socio-economic implications of a new technology, or working to address a societal challenge in a low-to-middle income country, problems that encompass social, technical and/or economic uncertainty, significant variations in involved stakeholder characteristics, and even subtle differences across the focal environment, inevitably benefit from a holistic analysis that spans multiple levels of abstraction, encompasses a plurality of perspectives, and can be tailored to include contextual nuances. In addition, and perhaps most importantly, these types of problems require an accurate definition of the problem to be solved. To foster effective progress in this class of challenges, we herein introduce a novel problem analysis method, termed Comprehensive Success Factor Analysis (CSFA), that provides a rigorous and structured approach to attain holistic problem frames across an array of challenge types to inform decision making, innovation, and capacity building with the goal of achieving impact at scale.
ANALISIS CEMARAN BAKTERI E. coli PADA AIR KOLAM RENANG UMUM DI KABUPATEN TANGERANG DENGAN METODE MPN (MOST PROBABLE NUMBER)
Authors: Safitri Laili , Djasfar Seftiwan Pratami
Published: August 2023

Air merupakan kebutuhan manusia, begitu juga dengan air kolam renang yang sering digunakan untuk rekreasi maupun olah raga. Kolam renang kini telah berkembang pesat di berbagai daerah termasuk Kabupaten Tangerang. Oleh karena itu, air kolam renang harus sesuai dengan Standar Baku Mutu Kesehatan Lingkungan berdasarkan Peraturan Departemen Kesehatan RI Nomor 32 Tahun 2017. Tujuan dari penelitian ini adalah untuk menghitung cemaran bakteri E. coli pada air kolam renang umum di Kabupaten Tangerang berdasarkan Standar Permenkes No 32 Tahun 2017. Bakteri E. coli menjadi salah satu spesies utama dalam subkelompok fecal coliform karena sifatnya yang lebih spesifik karena umumnya tidak tumbuh di lingkungan secara bebas. Metode yang digunakan dalam penelitian ini adalah metode MPN yaitu suatu metode analisis kuantitatif untuk menentukan jumlah mikrooganisme target pada sampel yang dilakukan dengan dua tahapan, yaitu uji pendugaan dan uji penegasan. Uji pendugaan dilakukan dengan menggunakan media Lactose Broth (LB). Kemudian tabung dengan sampel yang positif dilanjutkan ke tahap dua yaitu uji konfirmasi yang dilakukan dengan media Briliant Green Lactose Broth untuk menghitung jumlah bakteri Coliform kelompok E. coli lalu dirujuk ke tabel Thomas. Pada penelitian ini didapatkan hasil berupa 2 dari 3 sampel positif E. coli dan 1 dari 2 sampel positif tersebut, nilainya berada di atas ambang batas ketentuan Peraturan Departemen Kesehatan RI Nomor 32 Tahun 2017 yaitu < 1 colony form unit (cfu)/100 ml sampel yang diperiksa setiap bulan. Dimana kolam A adalah 0 CFU/100ml, kolam B adalah 0,911 CFU/100ml dan kolam C adalah 1,070 CFU/100ml.
Improving Performance and Energy Efficiency of the Classification of Data Streams on Edge Computing
Authors: Luna Reginaldo , Cassales Guilherme , Senger Hermes
Published: August 2023

In this work, we propose a loop transformation to improve performance and energy efficiency of ensembles. We compare the performance of our technique with three other strategies for improving energy efficiency and throughput in data stream classification using six state-of-the-art ensemble algorithms and four benchmark datasets. Our results show that software strategies can significantly reduce energy consumption. Mini-batching improved energy efficiency by 96% on average and 169% in the best case. Likewise, mini-batching with loop fusion improved energy efficiency by 136% on average and 456% in the best case.
Gestão de Recursos para Computação em Nuvem usando Escolha Social Computacional
Authors: Furquim Felipe V. , Cordeiro Daniel
Published: August 2023

A gestão de recursos em plataformas de Computação em Nuvem envolve vários campos de como recursos computacionais são compartilhados entre usuários. Diversas decisões são tomadas tanto no lado do provedor quanto no lado do usuário, assim ambos os lados têm um intrínseco senso de prioridade: tem algumas opções que são melhores que outras, de acordo com algum critério, mas todas elas cobrem as necessidades computacionais do usuário, respeitando as restrições de disponibilidade do provedor. Essas preferências não são propriamente diferenciadas por algoritmos tradicionais de gestão de recursos. Esta pesquisa tem como objetivo projetar sistemas de tomada de decisões que agreguem as preferências de diferentes atores, utilizando conceitos da Teoria da Escolha Social Computacional com tomada de decisão strategyproof.
Simplifying HPC Application Development with OpenMP Cluster and Unified Memory
Authors: Cléto Jhonatan , Yviquel Hervé , Pereira Marcio M. , Araújo Guido
Published: August 2023

As accelerators such as GPU and FPGA become more common in HPC systems, programming for these systems becomes more challenging due to, for example, the additional layer of memory management. This paper presents an extension to the OpenMP Cluster that integrates CUDA’s Unified Memory management. Evaluation using a synthetic benchmark reveals that while this extension simplifies the development of GPU-based OMPC applications, further optimization is required to reduce its impact on performance.
Simulação de Sistemas Exascale usando Time Warp
Authors: Fares Ricardo Trivizan , Manacero Aleardo , Barroso João Pedro R. , Genova Lucas E. , Juiz Gustavo T. , Lobato Renata S. , Spolon Roberta
Published: August 2023

A análise de sistemas computacionais exascale, quando feita por sua simulação, exige enorme custo computacional e de tempo que inviabiliza sua análise em simuladores sequenciais. À vista disso, a simulação distribuída torna propício a análise de tais sistemas complexos. Entretanto, a partilha da simulação em um sistema distribuído origina o problema da sincronização. Assim, este trabalho propõe a extensão do simulador iSPD (iconic Simulator of Parallel and Distributed Systems) usando o protocolo de sincronização otimista Time Warp viabilizando a simulação de sistemas exascale em tempo hábil.
A tool for profiling memory accesses locality on NUMA architectures
Authors: Machado Letícia S. F. , Senger Hermes , Tadonki Claude
Published: August 2023

In this paper, we studied the NUMA architecture and memory access patterns presented by applications executing in this architecture. We developed a tool to parse the source code of a target application and produce traces about which memories of the NUMA node were accessed and in which order. Based on these traces, we expect to get insights into strategies to optimize the performance of the target applications. We will apply this tool to improve the performance of a wave equation simulator which is the kernel of a seismic imaging application for the Oil and Gas industry.
Integração de Simuladores no Contexto Militar: Análise da Viabilidade de um RTI de Código Aberto
Authors: Rosa João Rodolfo de Oliveira , Fazenda Álvaro Luiz
Published: August 2023

Esta pesquisa tem por objetivo verificar a viabilidade de emprego de RTI de código aberto para integração de simuladores em um contexto militar. Baseia-se nos trabalhos desenvolvidos por Gütlein et al (2020). O RTI trata-se do middleware definido na Arquitetura de Alto Nível, HLA, que possibilita a interação entre diferentes sistemas de simulação, a partir de dados previamente acordados (FOM)
Near Real-time Stress Prediction for Patients with Disturbed Allostatic Load
Authors: Fröhlich William da Rosa , Rigo Sandro José , Bez Marta
Published: August 2023

Stress is one relevant cause of diseases nowadays, and prolonged exposure to stress can cause a disturbance in the allostatic load. Alternatives have been sought to deal with this situation and verify the impact of this allostatic load disorder. Wearable sensors are an option for automatically identifying acute stress since they can measure signs such as electrocardiogram, heart rate, electroencephalogram, electromyogram, or galvanic skin response. All these signals have intrinsic characteristics in a normal state and change if associated with stress occurrence. The literature presents Machine Learning Approaches and Deep Learning Models as alternatives to pattern detection in physiological signals. Nevertheless, we identify a gap regarding the allostatic load impact identification and the real-time classification when using these models. this article aims to acquire data in stress induction experiments in clinical and non-clinical patients, train a machine learning model, and, in sequence, carry out a new experiment to evaluate the classification in near real-time. The classification experiment presented results with accuracy above 92.72%. When it comes to real-time classification experiments we obtained an accuracy of 78.93%. Evaluating participants in experiments divided into clinical and non-clinical groups, a decrease of 5% in precision was identified. Based on the results obtained, we verified that the allostatic load can present challenges for real-time stress classification.
Human-centered algorithmic composition for well-being music
Authors: Gonçalves Junior Clenio B. , Neris Vânia Paula de Almeida
Published: August 2023

The use of music to bring about health benefits is a well-established practice the outcomes of which have been confirmed by research in recent years. By leveraging this capability, the algorithmic composition aimed at producing specific effects on the listener has become a growing field for the automatic creation of well-being music. This work makes a contribution to this field, through a documentary investigative study that puts forward a comprehensive set of human-centered features that should be included in the algorithmic composition of music for well-being. The results are based on a systematic review of 60 papers published in the last few years. The set is divided into categories as a means of assisting their use by the teams involved.
Toolbox for vessel X-ray angiography images simulation
Authors: Maccagnan Gabriela Copetti , Schmith Jean , Santos Marcia , Figueiredo Rodrigo Marques de
Published: August 2023

In recent years, automatic computer techniques have been proven to be a great tool for the rapid detection and disease diagnosis. The core of those diagnostic systems are usually artificial intelligent algorithms like convolutional neural networks, in which thousands of images are needed for training. However, the available datasets of biomedical images, specially for X-ray angiography, are scarce. Therefore, we propose a toolbox for X-ray angiography images simulation to increase the number of available images as an alternative to data augmentation method for training artificial intelligence algorithms. The toolbox was developed with a set of functions to simulate complex vessel structures, as well as stenosis and aneurysms, in X-ray angiography images.
Acompanhamento e Monitoramento de Movimentos de Indivíduos por Avatar 3D em Tempo Real em um Sistema Web de Telemedicina
Authors: Maciel Matheus , Lee Huei D. , Ensina Leandro A. , Takaki Weber S. R. , Ferraz Alexandre P. , Chung Wu F.
Published: August 2023

O Sistema de Monitoramento de Movimentos e Análise Remota em Telemedicina é uma aplicação web para monitorar e analisar o movimento de indivíduos com dados coletados de sensores inerciais. Atualmente, a aplicação limita-se a representação dos dados por meio de gráficos de linhas, dificultando a análise pormenorizada da respectiva atividade. Assim, o objetivo desse trabalho foi desenvolver e apresentar uma função de acompanhamento de movimentos por avatar em três dimensões em tempo real e avaliá-la pela mensuração do tempo de atraso no envio de dados. Os resultados demonstraram desempenho quantitativo satisfatório com delay inferior a 304 milissegundos, incluindo a validação técnica com especialistas do domínio.
A Differential Equation Based Model of Cell and Cytokine Activation Influenced by Glucose Dynamics and Elevated Cortisol Levels Due to Aging
Authors: Quintela Bárbara M. , Marins Thaís S. , Garan Steven A. , Suen Elliott K. , Talaei Kian , Martins Nuno R. B. , Jahansooz Julia R. , Piszker Walter
Published: August 2023

Immunosenescence refers to the alterations in the immune system that occur due to the aging process, which increases susceptibility to diseases and reduces vaccine efficacy. Consequently, understanding the impact of aging on the immune system is crucial for simulating the different ways in which it can be challenged, thereby increasing life expectancy and quality of life. This study combines two mathematical models to understand how cortisol affects and is affected by the glucose uptake and the proand anti-inflammatory cytokines under infection. Cortisol concentration follows a diurnal rhythm and increases with glucose intake. The model simulates the influence of cortisol on the immune response, specifically through cytokine regulation.
Análise da influência do tom de pele no sinal de fotopletismografia (PPG)
Authors: Rosa Ayame G. R. da , Schmith Jean , Figueiredo Rodrigo Marques de , Prade Lúcio R. , Pinheiro Janaína Avancini , Rigo Sandro
Published: August 2023

A fotopletismografia é uma importante técnica para o estudo dos parâmetros fisiológicos de saúde. A aquisição deste sinal é suscetível a muitos tipos de artefatos, como movimentação do paciente e ruído. O objetivo deste artigo é demonstrar o comportamento do sinal PPG medido na superfície anterior do punho, a fim de descrever a qualidade do sinal quando adquirido em diferentes tons de pele. Com isso, foram coletados 144 amostras de mil valores cada e, com a análise dos sinais, foi identificado que há um comportamento sensível do sinal PPG quando associado ao tom de pele.
Abordagem Computacional Baseada em Deep Learning para o Diagnóstico de Endometriose Profunda através de Imagens de Ressonância Magnética
Authors: Figueredo Weslley K. R. , Silva Italo F. S. da , Diniz João O. B. , Silva Aristófanes C. , Paiva Anselmo C. de , Salomão Alice C. C. Brandão , Oliveira Marco A. P. de
Published: August 2023

Endometriose é uma doença que atinge vários órgãos, principalmente aqueles na estrutura pélvica, e reduz consideravelmente a qualidade de vida da pessoa afetadas. A doença afeta, principalmente, mulheres em idade fértil. Pode ser identificada via exames de imagem. Neste trabalho, Propõe-se um método para identificação automática da lesão de endometriose em imagens de ressonância magnética usando técnicas de processamento de imagem e uma VGG-16 modificada, a fim de servir como auxílio no diagnóstico, na redução da necessidade da utilização de métodos invasivos para realização destes, o tempo de diagnóstico e os resultados falsos negativos. Acurácia de 83,89%, sensibilidade de 84,15%, e especificidade de 83,86% foram alcançadas.
Detecção de COVID-19 em Imagens de Raio-X de Tórax através de Seleção Automática de Pré-processamento e de Rede Neural Convolucional
Authors: Diniz João O. B. , Quintanilha Darlan B. P. , Carvalho Filho Antonio O. de , Gomes Jr Daniel L. , Silva Aristófanes C. , Braz Jr Geraldo , Paiva Anselmo C. de , Luz Daniel de S.
Published: August 2023

A COVID-19, mesmo com diminuição dos casos, é considerado um problema global, a detecção precoce ainda é relevante e pode ser crucial para salvar vidas. Este artigo apresenta um método para detecção automática de COVID-19 em raio-X de tórax usando seleção automática de melhoria de imagem e rede neural convolucional. O método usa pré-processamento de imagem para melhorar as características distintivas da COVID-19 em raio-X e seleciona uma rede neural convolucional para classificar as imagens. Os resultados mostram métricas relevantes com uma acurácia de 99,39% e F1 − Score de 98,71%. Essa abordagem pode ser valiosa para a triagem eficaz da doença, melhorando o tratamento e reduzindo as mortes relacionadas à COVID-19.