bluuebunny/crossref_metadata_2025 huggingface dataset:
Severe Acute Respiratory Syndrome Coronavirus 2 Virus-Like Particle and Its Application in Chinese Medical Research
Authors: Xu Ruo-Dan , Shi Ming-Fei , Li Jing , Li Ning
Published: March 2021

Background:

The global outbreak of coronavirus disease 2019 (COVID-19) has brought disastrous consequences to public health and medical systems, whereas no approved medications are currently available. Benefits of traditional Chinese medicine (TCM) against COVID -19 have been observed, however, the underlying mechanistic actions remain unclarified. Due to high pathogenicity and infectivity of the new coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]), the lack of access to SARS-CoV-2 and biosafety level 3 (P3) facilities has impeded scientific investigations of TCM against COVID-19. Though low-pathogenic coronavirus and pseudoviral systems have been applied to substitute SARS-CoV-2 in fundamental studies, both models cannot imitate virological and clinical features associated with SARS-CoV-2. The virus -like particle (VLP) is a virological model that is safe and could be performed without biosafety protections.

Aims and Objectives:

To construct VLP of SARS-CoV-2 containing structural proteins of authentic viruses and resembling the morphology, partial life cycle, and immunoreactions of natural virions, and to introduce VLP into Chinese medical research.

Materials and Methods:

Using mammalian expression system, we have currently constructed SARS-CoV-2 VLP containing four essential structural proteins.

Results:

Based on this model, we propose six aspects of research that could be carried out for TCM formulas in the fight against COVID-19.

Conclusion:

Application of the VLP model provides a safe methodology to strengthen the response systems of Chinese medicine in preventing and controlling newly identified infectious diseases and offers collaborative opportunities for interdisciplinary deciphering of molecular and biological basis of anti-viral TCM formulas.
Erigeron sumatrensis Retz. (Compositae), a recently recognized invasive alien species in Bosnia and Herzegovina
Authors: Maslo Semir , Šarić Šemso
Published: March 2021

Erigeron sumatrensis Retz. is native in South America, widely naturalized in Europe and has been recently recorded in Bosnia and Herzegovina. During the period of 2019-2020, it was recorded at 35 new localities in South Herzegovina and Central Bosnia. On the basis of the number of populations and the numbers of individuals within populations, we assume that this species is now invasive in Bosnia and Herzegovina.
Design Go-Kart Chassis Four Strokes 110 Engine
Authors: Misbachuddin
Published: March 2021

This study aimed to decide how to design a kart chassis and the strength of the welded joints. In this design, the chassis frame is made of tubular profile steel, which is designed to withstand most of the loads in a vehicle. The chassis was designed using a computer application, namely Auto CAD 2007. Assembly using carbon steel pipes connected using SMAW welding with E6013 RB 2.6 mm welding wire with a current of 75 A, 1G place. The test is carried out with a tensile testing machine. The material is pulled past the most stretch elasticity limit until finally, the specimen reaches the limit (breaks). The tensile test takes about 3-5 minutes with a load of 10-20N. The test results show the average tensile strength of the iron pipe is 0.512 Mpa.
Experience of therapeutic plasma exchange in rheumatic diseases: Albumin may be a suitable substitute for plasma
Authors: Bai Zhiqian , Chen Yu , Dong Lingli
Published: March 2021

Objectives: In this study, we aimed to assess the value of therapeutic plasma exchange (TPE) in the treatment of rheumatic diseases and compare the safety of different replacement fluids used in TPE.

Patients and methods: A total of 727 TPE procedures in 285 patients (57 males, 228 females; mean age: 39.7±15.4 years; range, 13 to 79 years) with rheumatic diseases between January 2011 and February 2019 were retrospectively analyzed. Data including demographic and clinical characteristics of the patients were recorded. Treatment response to TPE and adverse events were evaluated in all patients.

Results: Indications for TPE included 13 different disorders, with the majority being systemic lupus erythematosus (up to 50%). The mean number of TPE sessions was 2.55±1.00 per patient and the mean exchange plasma volume was 2,270±256 mL per session. Combined plasma and albumin was the most frequently used replacement fluid (69.5%), followed by albumin and plasma in 20.5% and 10.0% of episodes, respectively. Up to 73.7% (210/285) patients achieved clinical improvement after TPE treatment. Adverse events occurred in 15.1% (110/727) of all the procedures, and allergic reaction (34.5%) was the most common event. The overall incidence rate of complication was similar among the three types of replacement fluids (p=0.214).

Conclusion: Based on our study results, TPE is an invasive, but safe, useful and, sometimes, essential tool with an acceptable risk/benefit ratio for most rheumatic diseases. Albumin can be used as a feasible substitute for plasma in case of shortage of blood resources.
A COMPARATIVE STUDY OF GOMUTRA HARITAKI VATI AND MUSTADI VATI IN THE MANAGEMENT OF STHAULYA (W.S.R. TO OBESITY)
Authors: Mungara Vaidya Bharat , Kodrani Vaidya Priya
Published: March 2021

Sthaulya (Obesity) is among the diseases which are increasing in prevalence day by day. It is important to rule out it on time and get cured. Symptoms and complications of it have effect on daily work efficiency. This study was carried out on 30 patients having classical symptoms of Sthaulya. Patients were selected as per the inclusion, exclusion and diagnostic criteria. Patients were divided into two groups randomly. Group A was treated with Gomutra haritaki vati and Group B was treated with Mustadi vati for 8 weeks. Grade score were adopted for the assessment of the symptoms. The obtained data were analyzed statisti-cally. Probable action of Gomutra haritaki vati might be Srotobandh nashana, Malashodhana and Aama-paachana while of Mustadi vati might be Dhatushoshana, Rukshana, Lekhana. Thus, both drugs have beneficial effect in treating Sthaulya. This study includes 30 patients. In Group A, 20% patients were 100% cured, 66.66% had marked improvement and 13.33% patients had moderate improvement. In group B, 40% patients were 100% cured, 40% patients had marked improvement, 20% patients had mod-erate improvement. Group A showed 84.12% result while Group B showed 82.07% result.
AYURVED MANAGEMENT OF SECONDARY INFERTILITY - A CASE STUDY
Authors: Biradar Sujata. , Anand Asha
Published: March 2021

Infertility due to anovulatory cycles over recent years, has emerged as one of the most common health issues that many young women have been facing. Sedentary lifestyles with minimum physical activity, rising stress level and irregular sleep pattern are few of the reasons, according to many clinicians and health experts. PCOD is a common Endocrine disturbance affecting females of age group between 15-30 years. The disorder accounts for delayed periods, Infertility, obesity hirsutism and acne. According to modern science exact cause of disease is unknown. In Ayurveda all diseases of female reproductive system are classified under Yonivyapada, according to Ashtanga Hridayam 20 diseases of Vagina arises because of faulty food habits. PCOD is a kapha predominant disorder; kapha gets aggravated by consuming more sleshmika and sneha containing food items and by lethargic lifestyle. The line of treatment in modern medicine is Harmonal therapy. In Ayurveda the line of treatment is according to dosha predominance, here it is kaphahara, Strotoshodhaka and Anulomana. So, in the present study – Classical Virechana, Pushpadhanwa rasa, KanchanaraGugglu, Triphalvati, are selected. The result is outstanding, and symptoms subsided. Further clinical trials can be conducted to prove the efficacy of the drugs statistically.
EVALUATION OF THE EFFICACY OF DADRU VIDRAVANA MALAHARA IN DA-DRU KUSHTA- A RANDOMISED CONTROLLED CLINICAL STUDY
Authors: V S Nidhin , D’souza Zenica
Published: March 2021

Skin disorders are one among the common manifestations. Normally, 10-15% of the general practitioner’s encounter patients with skin disorders. Ayurveda covers a number of skin manifestations under Kushta Roga. Dadru is one among Kshudra Kushta. It is identified by symptoms such as Kandu, DeerghaPratana, Utsanna, Mandala, Raaga, Pidaka with predominance of Pitta Kapha Dosha. It can be correlated with Tinea infection. Being a Twak Vikara, Bahirparimarjana Chikitsa like Lepadhi treatments plays an im-portant role in the treatment of Kushta including Dadru Kushta. Present study was conducted on 60 diag-nosed patients of Dadru Kushta who were randomly allocated with 30 each in two groups. Dadru Vidra-vana Malahara was given for local application in one group and Gandhaka Malahara, a widely used for-mulation in clinical practice was given for local application in another group. These local applications were advised for a duration of 7 days for under the treatment concept of Lepa. The ingredients of which are the drugs processing Shodana and Kushtahara property. The data was collected from patients at baseline,4th day and 8th day (on completion). Assessment was based on KASI method of grading, number of lesions, perimeter of each lesion, pidaka (present or absent). The results of the study showed that, a statistically significant difference was not seen between the effect of Dadru Vidravana Malahara and Gandhaka Malahara in Dadru Kushta.
AN OBSERVATIONAL STUDY TO ASSESS THE STATUS OF AGNI IN MIGRAINE PATIENTS
Authors: M. A Reshma , K. N Anandalakshmy
Published: March 2021

The function of digestion and metabolism, which is unavoidable for the maintenance of life, is performed by the Agni. When Agni functions properly, the individual remains healthy and becomes diseased when the same is dis- turbed. Migraine is a common disabling primary headache disorder with high personal and social costs, but its pathophysiology is not yet fully understood. As all the diseases are caused by the hypo-functioning of agni, it is essential to understand the status of agni in migraine patients. 75 Patients diagnosed with migraine were selected from the OPD and IPD of Government Ayurveda College Hospital Kannur, before intervention. Then their status of agni was assessed by using a validated agni assessment tool. It was developed by considering the specific fea- tures assigned to four functional states of agni. Then their disability was assessed by using MIDAS score. Statisti- cal assessment was done by using descriptive statistics and spearman correlation coefficient. Status of agni in most of the migraine patients was not normal.
Keywords: Agni, Migraine disability, Samagni, Teekshnagni, Mandhagni, Vishamagni
SUTIKASRAVA (LOCHIA) IN AYURVEDA – AN OBSERVATIONAL STUDY
Authors: Pawar Divya , Gholap Sameer
Published: March 2021

Ayurveda gives importance to the care of mother and her baby at every phase of her life under antenatal care and post-natal care. A post-natal period comes just after the expulsion of placenta up to 6 weeks thus defined as Puerperium and duration called as Puerperium period. Lochia is a vaginal discharge for the first fortnight during puerperium. The discharge originates from the uterine body, cervix and vagina. It is a cleansing discharge which stays for ten or twelve days after delivery in common practice. Lochia is of 3 types Lochia Rubra, Lochia Serosa and Lochia Aba. In Ayurveda the term Sutika can be used only after the expulsion of placenta. Sutika is more prone to diseases due to aggravation of Doshas. Also, she is more prone to infections which is called as Lochial Infection. A 45 patient’s observational data collected from Ayurveda College for the study.
CLINICAL APPRAISAL OF PAPAYA KSHIRASUTRA IN THE MANAGEMENT OF FISTULA IN ANO (BHAGANDAR)
Authors: L. D Barik , S. K Debnath , D. S Sahu , J Hazra
Published: March 2021

Background: Fistula in Ano(Bhagandar) is most common and notorious disease among all anorectal dis-order and is prevalent in the populations worldwide and is second highest af-ter Arsha (hemorrhoids). Kshara Sutra (K.S.) is one of the chief modalities in the treatment of Bhagandara in Ayurvedic science. It produces inconveniences in routine life. It causes discomfort and pain that creates problem in day to day activities. Ksharsutra has been proved as a big revolution in the treatment of fistula in ano. To find out an effective alternative to Apamarga ksharasutra in view of easy processing taken papaya kshir sutra opted for this clinical study. Sushruta the father of ancient Indian sur-gery has paid great attention towards bhagandar and dealt it systemically. Material and Methods:30 cases of Fistula in Ano of either sex were selected from the OPD and IPD of the CARIDD Hospital Kolkata.They were subjected for ligation of papaya kshirasutra in the Operation Theatre of CARIDD,Kolkata for the study. Observation & Result : UCT have been detected as mentioned in the fol-lowing mentioned principle and found to be equally (slightly less as compared to as it is mentioned in the standard Apamarga ksharasutra therapy. Discussion Burning pain is less observed during the treatment of Papaya kshirasutra therapy. UCT is also equally observed which is slightly less than the standard Snuhi apamarga ksharasutra (Standard) therapy.
ROLE OF TAGARADI CAPSULE IN THE MANAGEMENT OF ANIDRA (INSONIA) – A CLINICAL STUDY
Authors: Jadav Rajnik , Dave Alankruta , Dabhi Swati
Published: March 2021

Anidra (Insomnia) is a type of sleep disorder in which individual feels difficulty in falling asleep, staying asleep or both. In Ayurveda, Anidra is indicated as VataNanatmajaVikara by Acharya Charaka. Insomnia affects most of the people at any stage of life due to today’s stressful day to day life. Allopathic hypnotic drugs are used to treat insomnia in acute stage, but long-term use can lead to dependency and withdrawal symptoms along with other side effects. In present study a polyherbal compound Tagaradi Capsule consist extracts of Tagara, Jatamansi, ParsikaYavani, Ashwagandha, Brahmi, Shankhapushpi, Pippalimula and Sarpagandha is used to check its efficacy in the management insomnia. Aim: Role of Tagaradi capsule in the management of Anidra (Insomnia).
Materials and methods: Total 33 newly diagnosed patients of age group 18 to 70 years of insomnia who were not taking any other hypnotic medicine were selected and administered 2 capsules each of 500 mg of Tagaradi compound extract along with a cup of warm milk at bedtime for 2 months. Assessment was done considering the overall improvement of sleep quality according to Pittsburgh Insomnia Rating Scale, im-provement in associated complains, relieving of anxiety according to Hamilton Anxiety rating Scale and relieving of depression according to Hamilton Depression Rating Scale. Observations: The information gathered on the basis of observations was subjected to statistical analysis. The Paired ‘t’ test was used to check the significance of objective criteria and Wilcoxon Signed Rank Test was used to check the signifi-cance to subjective criteria. Results: The results showed that the trial drug had highly significant effect on almost all the mentioned parameters of Insomnia.
COMPARATIVE STUDY OF DASAMOOLA KWATHA AND DASAMOOLARISHTA WITH SPECIAL REFERENCE TO THEIR METHOD OF PREPARATION AND USES
Authors: Sooriyaarachchi B. S. M. M. , N. V Vidya , Vaghela D. B.
Published: March 2021

Dasamoola denotes to a polyherbal Ayurvedic preparation containing ten specific roots of medicinal plants which include five tree species called ‘Brihat Panchamula’ and five shrub species called ‘Laghu Pancha-moola’. Dasamoola Kwatha and Dasamoolarishta are popular Dasamoola preparations in liquid form be-cause of their therapeutic effects. Therefore, they have been widely used for various disease conditions in Ayurveda. Dasamoola Kwatha is the decoction of Dasamoola whereas Dasamoola is a content of the Kwa-tha of Dasamoolarishta. Dasamoola Kwatha is varying with the condition for which it is used. This con-ceptual study was conducted by studying Ayurvedic Kwatha preparation, Sandhana Kalpana according to the Ayurvedic textbooks with the objective to compare the important ingredients of Dasamoola Kwatha and Dashamoolarishta. Also, modern scientific knowledge was explored in this study. The results of pre-sent study suggest that Kwatha and Arishta are the most suitable dosage forms of Dasamoola for the treat-ment of various disease conditions. Further findings also support that the traditional uses of different varie-ties of Dasamoola Kwatha have been designed specifically to address the individualized disease condition. When preparing a medicine for an individual patient, the traditional medical practitioners ideally take into account as such things of the patient more importantly affected Dosha, strength of the digestive fire, body tissues affected and the accumulated toxins. This shows that the Ayurvedic and Traditional preparations are often complex in their composition which is responsible for various functions, such as balancing, stim-ulating, cleansing and nourishing which in turn stimulating the innate capacity of the body to heal itself.
A CONCEPTUAL STUDY TO UNDERSTAND THE PHYSIOLOGICAL PERSPECTIVE OF SHUKRA DHATU
Authors: Raj. A Resmy , Gawande Chitra. M.
Published: March 2021

Ayurveda is the ‘Science of Life’ and its aim is to maintain healthy status of healthy living being, i.e. pre-vention and treatment of disease. As per Ayurvedic Science, Purusha consists of three Dosha, seven Dhatu and three Mala which are the primary basis of living body. Dhatu are those which give support and strength to the body. Shukra is the seventh Dhatu, which is responsible for all systemic body activities in-cluding metabolic functions and performs specific functions of reproduction. According to Acharya Vagbhata and Charaka, Shukra is one which responsible for the process of Garbhotpadana (reproduc-tion). According to Susrutha, Shukra provides courage, nourishment, happiness, strength and production of offspring. Main objective of this study is to review the conceptual facts of Shukra Dhatu from different classical Ayurveda texts and to analyse the physiological perspective about the same. In this article, the classical references related to Shukra Dhatu is collected and tried to correlate the concept with modern physiological entities. From the available references in the Samhitas, Shukra Dhatu can be better co related to sperm along with semen, sex hormones (oestrogen, androgen etc.), and sex chromosome.
A REVIEW ON THE THERAPEUTIC EFFECTS OF NETI KRIYA
Authors: Jakhar Yogesh , Pathak Anupam
Published: March 2021

Yoga as an ancient science can help people live a long and healthy life. This science has now become in-creasingly popular in many countries. There are several health conditions that can be cured or at least alle-viated to a great extent, through the practice of this science. Yoga includes Asana, Pranayam and exercises that can help body, immunity, increase strength, weight loss, remove stress and relief from pains, infections and disorders. Some of the various yoga poses and techniques can be used to cure numerous conditions ranging from nasal polyps to cancer. Since a sinus infection is one of the most common respiratory ail-ments that people suffer from, it is only common for them to use natural practices to cure this condition. Yoga practice, which is known as Jala neti or Sutra neti, i.e., cleansing of nasal cavity, throat can help re-duce the pain and discomfort due to sinusitis, within a shorter period of time. These procedures are known as Neti kriya. Neti kriya is an integral part of shatkarmas / the six cleansing techniques that form the most important aspect of hatha yoga. Neti helps in preventing and managing upper respiratory tract diseases. An attempt is being made to collect and review articles that highlight the therapeutic effects of neti kriya. Data-bases like Pub Med (January 1980–April 2016), Scopus and Ayush Portal were searched. We used key-words like jala neti, neti kriya, neti combined with terms such as yoga, sinusitis, rhinitis, common cold, vision, snoring, nasopharyngeal carcinoma and mental health for the search. As only a few results were obtained, we reviewed relevant studies with saline nasal irrigation. Evidence emerging from this review suggests that neti offers manifold benefits and relief from the antibiotic grip. Most studies support the role of neti in treating sinusitis, rhino sinusitis, and allergic conditions and in improving vision. Jala neti has a significant role in improving the presence of mind and intelligence.
HOLISTIC APPROACH OF AYURVEDA TO ACHIEVE COMPLETE HEALTH AS
DESIRABLE BY WHO
Authors: Uttamram Yadav , Santoshkumar Bhatted
Published: March 2021

Health is a state of complete physical, mental, social, spiritual well-being, happiness of mind & senses, pleasant soul and not merely the absence of disease or infirmity. Ayurveda is a science of life, a system of health care and medicine which aims to guide people in living a healthy life. It provides knowledge of how to live and concentrates on the health and well-being of the individual as a whole, and as a member of so-ciety. In this competitive era with hectic schedules, it's the need of hour to follow certain dietetic and life-style guidelines for leading healthy and peaceful life. Today NCD’s are more common and a major chal-lenge to control them, so that we can follow do’s and don’ts of health dimensions as given in Ayurveda and we could reduce NCD’s burden across the globe.
EFFECT OF PANCHKARMA IN MYASTHENIA GRAVIS: A CASE REPORT
Authors: Joshi Atul , Awadhiya Amit , Keshari Neha , Thakar Anup
Published: March 2021

Myasthenia Gravis (MG) is a long-term neuromuscular disease that leads to varying degrees of skeletal muscle weakness. The condition is caused by breakdown in communication between nerves and muscles. The underlying defect is a decrease in the number of available acetylcholine receptors (AChRs) at neuro-muscular junctions due to an antibody mediated autoimmune attack.1 The most commonly affected mus-cles are those of the eyes, face and swallowing. The cause of this disease can be understood in view of Dhatavgnimaandhya, Vyana Vayu Vikriti. The present observation was conducted with an objective to find out the efficacy of Ayurvedic management in Myasthenia Gravis. Here is a case of 60 years old Hindu male who was diagnosed as Myasthenia Gravis (MG) reported with complaint of slurred speech, low pitch of voice, difficulty to open the mouth and to swallow food and difficulty in elevating right eyebrow since 6 months was registered in OPD of Panchakarma, IPGT & RA, Jamnagar. Considering the signs and symp-toms patient was treated on the line of Aavrita Vata Chikitsa, Sthanika Abhyanga with Bala Taila, Nasya with Anu Taila, Jihwa Pratisarana with Vacha Churna and Ghritapana before meal with Go Ghrita was administered. Treatment shows significant improvement in the symptoms without any side effects.
AYURVEDIC MANAGEMENT OF MENIERE’S DISEASE: A CASE REPORT
Authors: Mehta Bhoomi , Chaudhary Shraddha , D. B. Vaghela
Published: March 2021

Meniere’s disease is a disorder of internal ear, in which endolymphatic system is distended with endo-lymph. It is characterized by vertigo, sensory neural hearing loss, tinnitus and aural fullness. Bhrama, Kar-naksweda, Karnanada, Karnabadhirya can be compared with Meniere’s disease symptomatically. Howev-er, it is not possible to compare Meniere’s diseases with any Ayurvedic disease. Here treatment protocol used was Dhanvayas Kwatha, Punarnavashtaka Kwatha, Eranda Bhrusta Haritaki internally with Ksheera Bala Taila Nasya and Asanbilwadi Taila Karnapoorana. After 3 months of treatment patient got relief from vertigo and tinnitus and mild hearing loss persist. Hence the single case report shows that Ayurvedic management of Meniere’s disease gives excellent result.
CASE SERIES OF AYURVEDIC TREATMENT OF VALVULAR DEFECTS
Authors: Shinde Sanyogita Surendra , Vaidya Minal S.
Published: March 2021

Cardiovascular diseases (CVDs) are the number 1 cause of death globally, taking an estimated 17.9 million lives each year1. A case series of four patients is presented with differing results with the same drug as their treatment. 4 patients with valvular defects but with different underlying cause are discussed here. For the CVD patients were given purely Ayurvedic treatment along with their previous medicines, so as to see the result of the medicine. Baladya Ghrit a combination of drugs is chosen from Ayurvedic text commentary on Agnivesh Samhita by Acharya Chakrapanidutta. 4 patients were assessed to have valvular defects by 2Decho, here attempt is made by using Baladya Ghrit orally. 4 patients with different histories, 3 of them show significant result, one patient did not show any change. Here a focus on Hridroga is made to understand the action of Baladya Ghrit on different patients. A question can be raised that if this drug did not work for that one patient, what is the reason and is there a scope of studying this topic further? A relevant, scientific study should be done to access the Hridroga with various aspects in Ayurvedic treatment given.
JALAUKAVACHARAN AND DIETARY INTERVENTION IN TWAKA VIKAR (VICHARCHIKA): A CASE STUDY
Authors: Babar Ramchandra P. , Babar Shravani R.
Published: March 2021

Currently observed that the sedentary lifestyle and stressed work schedule has increased the number of skin disorders (Twaka Vikara). It has been established fact that the common cause of various skin disorders (Twaka Vikara) is altered Ahara and Vihara (Dietary and Lifestyle changes), specially Viruddhaahar (in-compatible diet). Ancient Ayurveda Scholars described in detail Raktamokshana (the procedure of remov-ing the vitiated blood) for the management of the diseases caused by Rakta and Pitta. The Jalaukavacha-ran (Leech therapy) is one of the effective Raktamokshan (bloodletting) management of vitiated Rakta and Pitta caused skin disorders. In Jalaukavacharan the anti-coagulant property of hirudin, contained in leech saliva, lead to wider therapeutic application in prevention and treatment of various Twaka vikara. Twaka Vikara (Vicharchika) is one of the mostly observed skin disease, which is mainly developed on account of misconduct in all aspect including kayik, vachik, manasik variety of misconducts along with dietary and lifestyle irregularities. Dietary intervention and lifestyle modification play an important role to cure the diseases. In Present case study Patient showing symptoms of Vicharchika (Twaka Vikara) having improper dietary habits and stressed work schedule, after the Dietary Regimen and lifestyle modification along with Jalaukavacharan at local area showed improvement in skin texture. The details of the causative factors, clinical findings, improvements observed after implementation of preventive and curative management plans are presented here.
GRIDRASI: A CASE STUDY
Authors: O Sruthi.
Published: March 2021

In the present era, sedentary lifestyle is creating lot of problems in the human body. Gridrasi is a painful condition in which the person cannot sit and walk properly which in turn hampers his normal activity. Almost all signs and symptoms of Gridrasi resembles the condition Sciatica, as described in the modern texts. Sciatica is a very painful condition in which pain begins in lumbar region and radiates along the posterior lateral aspect of thigh and leg along with difficulty in walking. SLR, Slump test, Lasegue’s signs, Faber’s test is helpful not only to diagnose the sciatica but also to assess the progress of the therapy. A 49-year-old male patient working as a carpenter came to KVG Ayurveda Medical college KC, OPD complaining of low back pain radiating to posterior aspect of left lower limb for one month. Also, difficulty in walking and numbness in the left foot. He was diagnosed as a case of intervertebral disc prolapse at L4 - L5. According to symptoms it was diagnosed as Vata Kaphaja Gridrasi, treated with medicine like RasanaerandathiKashayam, Trayodasangguggulu, SarvangaChoornapindaswedam, Sarvangapathrapindasweda, Basthi, Sahacharadikashayam, Rasanadhiguggulu etc. After the treatment patient’s overall quality of life was significantly improved. The present case study is about the successful Ayurvedic management of Gridrasi.
USE OF UTTAR BASTI IN SECONDARY INFERTILITY WITH CHOCOLATE CYST – A CASE STUDY
Authors: Kalyani Parinita Prakash
Published: March 2021

Women are worshipped as Goddess due to their ability of bringing new life on earth. During reproductive period of women’s life there are varieties of ovarian cysts formation which leads to menstrual disturbance which might further lead to infertility. In recent years there is gradual rise in detection of ovarian cysts due to advance diagnostics. There is prevalence of 17 to 44% of ovarian cysts formation during reproductive phase. In this article, a case report regarding a patient of age 30 years having previous H/O bilateral choco-late cyst with both tubes thick with endometriosis and laparoscopic findings s/o impatiens tubes. For which patient had undergone laparoscopic aspiration. She was again diagnosed with recurrence of chocolate cyst by ultrasonography for that she came to my OPD for treatment. In Ayurveda it is stated that Shuddha yoni, Ambu, Beej and Kshetra are needed for Garbhadharan. Treatment plan was Shodhana, Uttar Basti with lekhandravyas and Shamanachikitsa. After 3 months of treatment regimen ultrasonography and hyster-osalpingography were repeated and reports revealed that previous mentioned left ovarian com-plex/haemorrhagic cyst is not seen, and tubes are patent. Hence, case study confirms that we can treat chocolate cyst with the help of Uttar Basti and Shamanachikitsa which acts as Lekhan and normalizes Vat-adosha and Raktadosha.
HUMAN RESOURCE COSTS AND FINANCIAL PERFORMANCE OF QUOTED COMPANIES IN NIGERIA
Authors: Onyekwelu CO , Akani FN
Published: March 2021

Accounting from the very beginning is confined to record only those business transactions which can be expressed in monetary terms. This study seeks to empirically investigate the relationship between human resource costs and financial performance of quoted companies in Nigeria. Panel data on different types of human resource costs and financial performance spanning from 2016-2017 were collected from financial reports and accounts of quoted companies on Nigeria stock exchange and federal Inland Revenue Service. Ordinary Least Square Multiple Regression, Auto Regressive Lag. Augmented Dickey-Fuller, Co-integration test, Granger Causality Test, Error Correction Model was used in analyzing the data with the aid of E-view version 12. The empirical results indicate that human resource cost significantly relate to financial performance, explaining about 80.1% of the total variation in revenue, human resource accounting were found to significantly relate to financial performance. The study conclude that human resource cost relate positively and significantly to financial performance and recommends that Management should not recruit more staff and should consider retaining only efficient staff, this implies that insurance firms should downsize their number of staff and focus on training and re-training of the most efficient members of staff. Management should make retirement benefits attractive so as to attract best brains to their respective firms, and there should be a well-coordinated program for staff development if the firm’s profitability and performance are desired to increase positively.
Federaciones, actividades deportivas y medio natural. Sobre la viabilidad de algunas funciones públicas delegadas
Authors: Jiménez Soto Ignacio
Published: March 2021

RESUMEN:

El incremento de personas que deciden utilizar el medio natural en sus ratos de ocio, es cada día mayor, destacando entre éstas quienes eligen la práctica deportiva con fines no competitivos, sino de placer y recreación, convirtiéndose en un usuario cualificado, al que la nueva legislación deportiva autonómica, como es el caso de la Ley 5/2016, de 19 de julio, del Deporte de Andalucía, le permite pertenecer a una federación deportiva no solamente con la tradicional licencia federativa, dedicada al deporte de competición oficial, sino también con un título habilitante para los deportistas de ocio. Con esta nueva inclusión de los deportistas en las estructuras federativas, se fortalece el asociacionismo deportivo, por lo que las federaciones deportivas relacionadas con el deporte en el medio natural pueden colaborar en la protección y conservación del medio ambiente, al incorporar estas actividades en el ámbito de las funciones públicas delegadas, asistiendo a una nueva técnica de control administrativo distinta a la de policía, y sí a través de la autorregulación regulada para determinadas actividades y en determinados lugares, destacando por su importancia los Espacios Naturales protegido (ENP). Funciones públicas delegadas que ya están realizados algunas federaciones deportivas, en este caso Montaña y Escalada en la homologación de senderos, a los que nos vamos a referir en el análisis de la posibilidad del ejercicio de la potestad expropiatoria cuando discurren por fincas privadas; igualmente, se realiza un estudio sobre el ejercicio de la potestad disciplinaria en el esquí y sus especialidades a través de la licencia o título habilitante, dentro del compendio de facultades públicas delegadas.
Noticias de Revistas Autonómicas
Authors: Fernández Ramos Severiano
Published: March 2021

SUMARIO:

1.- Unión Europea, Comunidades Autónomas. Derecho autonómico. Distribución de competencias 2.- Administraciones Públicas.Función Pública. 3.-  Derechos Fundamentales.Potestad Reglamentaria. Acto. Procedimiento administrativo y Contratación. Control Jurisdiccional de las Administraciones Públicas. 4.-  Hacienda pública, Bienes, expropiación y responsabilidad. 5.-  Modalidades administrativas de Intervención (Policía, Fomento, Servicio público, Actividad Sancionadora, Arbitral y Planificadora).6.-  Sectores Administrativos de Intervención. Derecho Administrativo económico. (Aguas, Montes, Minas, Costas, Agricultura y pesca, Urbanismo y Ordenación del territorio, Medio ambiente, Energía, Telecomunicaciones, Patrimonio cultural, etc.).7.-  Varia.
Dietary lipid levels requirements of hybrid yellow catfish (Pelteobagrus fulvidraco × P. vachelli
Authors: Mamuru Gobeng L.S. , Qiang Jun , Tao Yi-Fan , Chen De-Ju , Bao Jing-Wen , Ngoepe Tlou K. , Zhu Hao-Jun , Li Hong-Xia , Xu Pao
Published: March 2021

A 12-week feeding trial was conducted to determine the dietary lipid levels requirements of hybrid yellow catfish using pelleted diets containing six different lipid levels formulated to contain graded levels of 0.0% (control), 3.4%, 6.8%, 10.2%, 13.6%, and 17% of dry matter. A total of 504 juveniles with an average initial body weight of 8.77±0.012 g were randomly divided into 6 groups containing 3 triplicates with 28 fish per tank and fed each of the experimental diets. Results showed that maximal final body weight, weight gained and specific growth rate were significantly higher in the groups fed 3.4%, 6.8%, and 10.2% compared with that of groups fed 13.6% and 17.0% (P < 0.05). Feed conversion ratio and protein efficiency ratio were significantly lowered in the 6.8% and 10.2% groups (P < 0.05). The hepatosomatic index had no significant difference (P > 0.05) while the viscerosomatic index significantly decreased in 6.8% and 10.2% groups. White blood cells, red blood cells, hematocrit and platelets levels significantly increased in the decreased dietary lipids levels (P < 0.05) while hemoglobin had no observed significant difference (P > 0.05). Serum alanine aminotransferase, aspartate transaminase, total protein, total cholesterol, triglyceride and glucose were significantly influenced by the dietary lipid levels. Liver superoxide dismutase and catalase concentration decreased significantly in the 6.8% and 10.2% groups. Malondialdehyde increased in 6.8% and 10.2% groups. Glutathione peroxide showed insignificant results (P > 0.05). Study results suggested that, dietary lipid levels containing 3.4%,6.8% and 10.2% significantly influenced growth, blood function, antioxidant status and strengthened immune response in hybrid yellow catfish while higher dietary lipid levels (13.6% and 17.0%) decreased body weight and weakened immunity.
How Is The Internet Usage Pattern Among Women Self-Employed? An Analysis Of The National Labor Force Survey (Sakernas)
Authors: Suwadji Yuniarti Tri
Published: March 2021

Di era digital ini, perempuan cenderung keluar dari pekerjaan formalnya untuk berwirausaha. Mereka masuk ke wirausaha karena menawarkan lebih banyak waktu di rumah sehingga mereka tetap bisa mengurus rumah tangga. Tujuan dari penelitian ini adalah untuk mengetahui pola penggunaan Internet yang dilakukan oleh perempuan yang berwirausaha yang sudah menikah. Studi ini menginvestigasi fenomena tersebut dengan menganalisis data Survey Angkatan Kerja Nasional (SAKERNAS) dan mereview berbagai literatur yang sudah ada sebelumnya khususnya mengenai perempuan yang berwirausaha yang memanfaatkan Internet sebagai alat teknologi digital dalam pekerjaannya guna menunjang kinerja usahanya, sedangkan penelitian sebelumnya hanya berfokus pada pengukuran frekuensi. mengakses aplikasi Internet dan mengabaikan status perkawinan mereka. Hasil penelitian menunjukkan bahwa karakteristik orang yang menggunakan Internet untuk melakukan pekerjaan utamanya kebanyakan berasal dari daerah perkotaan, tamat pendidikan tingkat SMA, terbilang muda, dan sudah menikah. Adapun perempuan yang berwirausaha baik yang sudah menikah maupun yang belum menikah memiliki kecenderungan mengakses internet agar dapat memberikan kemudahan bagi mereka dalam berkomunikasi dengan konsumen, mempromosikan produk mereka dan bertransaksi dengan konsumen.

 

Kata kunci: perempuan, wirausaha, penggunaan internet
formation of information and analytical competencies of a library specialist
Authors:   Tashkent University information technologies named after Muhammad al-Khwarizmi, Arakelov Sergey
Published: March 2021

This article discusses the need for the formation of information and analytical competencies in the process of preparing library specialists for the information and library institutions of the republic during the transition to the digital economy
Ecological evaluation of the urban soil in Perm
Authors: Maslennikova Irina L. , Shishkin Mihail A. , Sherstobitova Natal’ya P. , Kuznetsova Marina V.
Published: March 2021

Introduction. Representations of the impact of anthropogenesis processes on the soil’s ecological state are the basis for improvement of the environmental pollution monitoring system to make correct architectural and planning decisions. Material and methods. During 2016-2018 an environmental assessment of pollution of 214 samples of urban soils was performed. The soil analysis was carried out according to a random sample as one test site per 1 km². The concentration of heavy metals was determined by atomic absorption spectrometry. The analysis of organic compounds was carried out by gas chromatography-mass spectrometry. The total number of heterotrophic and gram-negative bacteria of the Enterobacteriaceae family was determined by direct seeding on selective media. Statistical data processing was carried out using software Statistica. Results. The level of chemical contamination with water-soluble forms of heavy metals of Perm soils was assessed. The concentration of heavy metals Cu, Pb, Zn, Fe, Cd, Ni, Mn in the control samples of sandy/loamy soils was 0.09/0.15; 0.08/0.22; 0.22/0.39; 5.57/16.14; 0.02/0.01; 0.06/0.13; 0.74/3.14 mg/l, respectively. The values of the total pollution index (Zc) above 16 were recorded at 4.7% of the soil samples, which corresponds to a moderate degree of pollution. It was shown that the soil type influenced Zc (KW-H (3; 214) = 30.73; p = 0.00001) and amounted to 6.24 ± 3.72 for loamy soils; for peat - 22.42 ± 12.32; for sand - 9.23 ± 5.70; for old urban soils - 8.37 ± 4.07. The median of the heterotroph bacteria content in the soils for I (Zc: 0-4) and IV (Zc ≤ 16) groups was revealed to correspond to the categories of «poor,» II (Zc: 4-8) and III (Zc: 8-16) groups - «inferior» soil. A correlation between the content of heterotrophs and the number of bacteria E. coli was not detected. According to Zc, for each soil group, no statistical differences in phthalate content were noted. Conclusion. Environmental assessment of soils should be comprehensive, as the types of anthropogenic chemical pollution, that have varying degrees of correlations between each other, affect quantitative changes in soil microbiota, which in the future may determine the ability to maintain homeostasis in this ecosystem.
Characteristics of anthropometric and physiometric indices of volgograd schoolchildren in dynamics over 1976–2018
Authors: Latyshevskaya Natalia I. , Davydenko Lyudmila A. , Shestopalova Yelena L. , Levchenko Natalia V. , Yachontova Yekaterina V.
Published: March 2021

Introduction. The state of physical development of children and adolescents is an objective criterion of health. It is accepted to be most crucial index for predicting further child development, his readiness for sports, working life, and planning of training loads during physical education. Material and methods. The monitoring group included 7-17-year schoolchildren (820 girls, 748 boys). The body height, weight, chest circumference, the vital capacity of the lungs, the muscle strength of the hands were measured (standard techniques and instruments). A comparative assessment of the obtained indices with similar data of 1976, 2000 was performed. Results. The body height of schoolchildren decreased over the period 1976/2018, there was an increase in body of body weight. The chest circumference trend was uncertain: dropped (boys - 7,8, girls 7, 12-15 years old); increased ( boys 9-15, girls 8-11,16,17 years old). The increase in the lung vital capacity was noted mostly in boys, muscle force of the hands decreased ( boys 10, 13, 16, girls 15-16 years old ). The Stange test values have doubled in the dynamics of 7-17 years, the Genchi test increased by 73.1% for boys and by 8-10% for girls. Conclusion. The revealed features of the dynamics of anthropometrics and functional indices of schoolchildren argue the need to correct physical education programs, including the tolerance motor and power loads.
Selenium status of urban residents on the territory of the Crimean peninsula
Authors: Evstafeva Elena V. , Golubkina Nadezhda A. , Boyarinceva Yulia A. , Bogdanova Anna M. , Tymchenko Svitlana L.
Published: March 2021

Introduction. Considering the essential biological role of selenium, including its role in preventing cardiovascular diseases and its widespread deficit in soils, assessing selenium status for Crimean region inhabitants is an actual task. Material and methods. Determination of selenium content in hair as index the of long-term element’s intake into the human body by all pathways were determined by the fluorometric method in 46 inhabitants (18-20 years old) from city Simferopol. Additionally, the selenium was determined in water and food products in Simferopol and nearby residential territories. Results. Selenium content in most residents’ hair varied from 210 to 309 mcg/kg and 12-40% less than the normal range’s lower limit. These results show the selenium deficiency in urban residents from the Crimean region, mainly due to the low content of this element in cereal products and, to a less degree, - in water. However, most food products, which are the primary source of selenium in Crimean inhabitants’ diet, are delivered from other Russian regions. So it’s possible to assess the selenium supply of inhabitants, but it is not possible to make a total conclusion about the selenium status of the region. Conclusion. The revealed deficiency of selenium in Crimean region inhabitants and the literature data about the positive and close relationship between hyposelenosis and the quality of public health requires the extensive monitoring of the selenium content in soils and crop production the Crimean peninsula territory.
İSTANBUL SÖZLEŞMESİNİN, KADINA YÖNELİK ŞİDDETİ ÖNLEMEYE ETKİSİNİN SİYASİ PARTİ KADIN KOLLARI ÜYELERİ AÇISINDAN DEĞERLENDİRİLMESİ
Authors: ZERE Fatih
Published: March 2021

Şiddet, bir insan hakları ihlali olarak kabul görmektedir. Kadın ve çocuklar ise şiddetten en fazla etkilenen kesimdir. Her ülke yönetimi adli önlemlerle beraber toplumsal farkındalığı geliştirici tedbirler alarak şiddetle mücadele etmeye çalışmaktadır. İstanbul Sözleşmesi de bu anlamda ülkeler arası yeknesaklığı sağlayan önemli bir belge olarak karşımıza çıkmaktadır. Yapılan çalışmada kadına yönelik şiddeti önlemek üzere imzalanan bu sözleşmenin kadına yönelik şiddeti önlemede ne kadar etkili olduğunu öğrenmek üzere, Zonguldak ili Karadeniz Ereğli ilçesinde yer alan siyasi partilerin kadın kolları üyelerine çeşitli sorular yöneltilmiştir. Çalışma bulguları, kadına uygulanan şiddet çeşitleri ile İstanbul Sözleşmesi’nin bu şiddeti engellemedeki etkilerini içermektedir. Bu doğrultuda katılımcılar başta eğitim ve ekonomik özgürlükler olmak üzere toplum yapısı ve örf-adetlerin etkisini dile getirmişlerdir. Ayrıca resmi kurumlarda görev yapan personelin tutumu ile kadınların sözleşmeye ve kadına şiddete bakış açılarını da değerlendirmişlerdir. Sonuç olarak başta kadınların eğitimi olmak üzere toplumsal bir farkındalık ve devletin kararlı tutumu ile kadına yönelik şiddetin önemli ölçüde azalabileceği söylenebilmektedir.
Çocukluk çağında paratiroid hormon bağımlı hiperkalsemi: üç olgu nedeni ile
Authors: DERETARLA Kübra , TÖREL ERGÜR Ayça , PAMPAL Arzu , KAYMAZ Esin
Published: March 2021

Ciddi çocukluk çağı hiperkalsemisi, düzeltilmediği takdirde koma ve ölümle sonuçlanabilen ciddi bir bulgudur. Öte yandan etiyoloji ve tedavi yaklaşımları yaşa göre değişkenlik göstermektedir. Bu nedenle tanının doğru ve ivedilikle konulması önem arz eder. Ciddi çocukluk çağı hiperkalsemisi, düzeltilmediği takdirde koma ve ölümle sonuçlanabilen ciddi bir bulgudur. Öte yandan etiyoloji ve tedavi yaklaşımları yaşa göre değişkenlik göstermektedir. Bu nedenle tanının doğru ve ivedilikle konulması önem arz eder. Bu yazıda, hiperkalsemi saptanan üç farklı olguda tanı ve tedavi yaklaşımlarının literatür eşliğinde sunulması uygun görülmüştür.