bluuebunny/crossref_metadata_2025 huggingface dataset:
On special subgroups of fundamental group
Authors: Ayatollah Zadeh , Ebrahimifar Fatemeh , Mahmoodi Mohammad
Published: February 2021

Suppose ? is a nonzero cardinal number, I is an ideal on arc connected
Topological space X, and B?I(X) is the subgroup of ?1(X) (the first
fundamental group of X) generated by homotopy classes of ?_I loops. The main
aim of this text is to study B?I(X)s and compare them. Most interest is in
? ? {?,c} and I ? {Pfin(X), {?}}, where Pfin(X) denotes the collection of
all finite subsets of X. We denote B?{?}(X) with B?(X). We prove the
following statements: for arc connected topological spaces X and Y if
B?(X) is isomorphic to B?(Y) for all infinite cardinal number ?, then ?1(X)
is isomorphic to ?1(Y); there are arc connected topological spaces X and Y
such that ?1(X) is isomorphic to ?1(Y) but B?(X) is not isomorphic to B?(Y); for arc connected topological space X we have B?(X) ? Bc(X) ? ?1(X); for
Hawaiian earring X, the sets B?(X), Bc(X), and ?1(X) are pairwise distinct.
So B?(X)s and B?I(X)s will help us to classify the class of all arc connected
topological spaces with isomorphic fundamental groups.
Almost periodic and asymptotically almost periodic type functions in Lebesgue spaces with variable exponents Lp(x)
Authors: Diagana Toka , Kostic Marko
Published: February 2021

In this paper we introduce and analyze an important class of (asymptotically)
Stepanov almost periodic functions in the Lebesgue spaces with variable
exponents, which generalizes in a natural fashion all the (asymptotically)
almost periodic functions. We then make extensive use of these new functions
to study some abstract Volterra integro-differential equations in Banach
spaces including multi-valued ones.
Art nouveau in Zagreb: The new movement's significance to the profession of architecture
Authors: Cavlovic Melita , Smode-Cvitanovic Mojca , Uchytil Andrej
Published: February 2021

This paper traces the implications of Semper's Bekleidung theory on working
processes in the field of architecture in Zagreb. The idiosyncrasies of the
work of freshly graduated architects in a peripheral Austro-Hungarian city
are analysed, both in the context of developing and spreading the city block
system and the appearance of the new Art Nouveau style. Buildings in this
new modern style, which appeared in 1897, were built sporadically throughout
the city's urban fabric, which generally consisted of historicist
residential buildings at the time. Parallel to historicism, the demand for
Art Nouveau from clients grew, especially around the turn of the 20th
century. At the time, typical migration processes resulted in the arrival of
a well-educated populace that would commission Art Nouveau buildings in the
coming years. The unique characteristics of Art Nouveau style, especially
its ability to directly engage citizens and transmit messages of modern
times, proved to be an important determinant in its increasing popularity in
the city. Many professions and products were advertised on the fa?ades and
ornamentation of buildings, the main bearers of Art Nouveau style.
Using the ZOPA model to synergize the different interests of local and central authorities in an adaptive city plan towards flood resilience in Surakarta City, Indonesia
Authors: Miladan Nur , Permana Ariva
Published: February 2021

Surakarta City, a secondary city in Indonesia, has been threatened by floods
for many decades due to the overflow of rivers and an inadequate urban
drainage system. On top of that, inelastic time-bound city planning has made
the city susceptible to ever-increasing flood threats. The local authority
has attempted to minimize flood risk through particular structural
mitigations of the urban drainage system, which it has authority to do,
while the overall responsibility for flood control and river management is
under central authority. The different responsibilities of these two
different levels of authority have led to gaps and overlaps in relation to
the same objects of interest. On one hand, the city authority is concerned
with city planning, and on the other hand, the flood control and river
management authority is responsible for combatting flooding problems and
river management within the watershed. This issue is an interesting point to
investigate. In order for Surakarta to become a resilient city, it is
imperative to synergize the efforts of these two different levels of
authorities. This study aims to find the synergistic and optimal solutions
by means of a negotiated planning and management system that involves both
authorities. Critical evaluation and assessment of relevant documents, field
observations, and measurements, as well as acquiring expert opinions were
the main methods used in this study. We propose a ZOPA (Zone of Possible
Agreement) model to optimize agreement among the stakeholders. The model
essentially highlights the common interests and sets aside the conflicting
points among stakeholders. The study found that there are potential points
to negotiate with regard to the division of responsibilities through a
shared vision of the coordinated institutions and shared planning and
management in the direction of synergistic determination.
Subsidies and Countervailing Measures: Challenges in International Trade Law
Authors: Supriyo Agus , Wicaksana Prakasa Satria Unggul
Published: February 2021

In the global era with all demands and expectations for a better economic condition in a country that an international trade is needed. Fair competition can be carried out in competition between business actors and commodity (goods or services) in overseas with business actors and commodity (goods or services) in country. One form of creating justice in international trade competition is by providing subsidies. The issue of subsidies created the problems and disputes. The problem formulations of this research were: (1) how are the effects of subsidies and countervailing in international trade regulations? (2) how is the case analysis related to subsidies and countervailing measures according to the provisions of the GATT 1994, The SCM Agreement and other legal provisions? The results showed that (1) the effect of subsidies and countervailing measures based on their types (red light, yellow light, green light) in international trade regulations had provided clear provisions as well as the impact and limitations in implementing these provisions in accordance with the provisions. GATT 1994 and The SCM Agreement. (2) The several cases described regarding subsidies that were not allowed because they created injustice that the subsidies were only carried out in an emergency situation and their nature rescued them from an economic crisis.
Perlindungan Hukum Kreditor Dalam Warisan Atas Harta Peninggalan Tak Terurus Menurut Sistem Waris Barat
Authors: Rifaldi Setiawan Muhammad , Fakhry Muhammad , Apriano Mahardika
Published: February 2021

The enactment of inheritance law in Indonesia adheres to 3 (three) inheritance law systems, namely; First, Western Inheritance Law, Second, Customary Inheritance Law, Third, Islamic Inheritance Law. So that in Indonesia is known for the pluralism of inheritance law. The western inheritance legal system allows for heirs to reject the inheritance left by the heirs because there is a greater pasiva than the assets. then the status of the property will be an unmanageable inheritance. Doctrinal research method, which is a study that systematically examines the legal norms governing certain legal categories and analyzes the relationship between legal norms. In this case the state through the Heritage Hall that will manage the property. As a form of protection creditors can apply to be a replacement heir for the deposit of receivables will be carried out by the state through the Heritage Hall a number with the value of the heir's debt or or the value of the property or objects left by the heirs is sufficient.
Penyelesaian Tindak Pidana Pencurian Hewan Ternak Menurut Hukum Adat Masyarakat Kecamatan Alas Kota Madya Manufahi
Authors: Fernandes Vassalo Acacio
Published: February 2021

Theft is related to the possession of other property without the permission of the owner, with various ways and modes of operation. The role of customary law in the settlement of criminal theft (livestock) is the implementation of state duties in combating criminal acts. This is a manifestation of Article 2 paragraph (3) and Article 59 paragraph (4) of the RDTL Constitution. The application of customary law in the Alas District (Posto Administrativo) is a positive response to the high desire of the community about a peaceful and serene life in their environment. Therefore, the term law enforcement is closely related to the idea of the rule of law or legal principles as the supreme power in the rule of law and democracy in East Timor.
Penerapan Sanksi Pidana Perda Pajak dan Retribusi Bidang Pendapatan di Kota Ternate
Authors: Malik Faissal , Abdulajid Syawal
Published: February 2021

The application of regional regulations in the field of Regional Taxes and Retribution in Ternate City has not yet been submitted to the Court with criminal convictions, but it is realized that the regional regulation enforcement officers have not fulfilled the tax obligations. Even so, violations of the Tax and Retribution Regional Regulations on administrative law sanctions are chosen to be enforced rather than criminal sanctions because administrative legal sanctions are more effective in their enforcement. Therefore, the formation of regional regulations on taxes and levies does not only pay attention to aspects of legal substance, but also aspects of structure and cultural aspects, in the form of the availability of regional law enforcement officers which in turn result in enforcement of regional regulations on taxes and levies so that criminal sanctions can be utilized to increase original income. Regional (PAD).
Penyelesaian Sengketa Adat Mengenai Tapal Batas Antara Desa Pakraman Penatih Puri dan Desa Pakraman Peguyangan
Authors: Adi Trinaya Dewi A.A. Mas
Published: February 2021

Blurred village boundaries can cause confusion in the implementation of village services, pawedalan, punia funds, kasucianism and non-compliance for local residents. This condition is believed by Hindus to cause disruption of social balance (sekala) and magic (niskala). As a result of the unclear territorial boundaries of the Pakraman village, there was a customary reaction in Pakraman Penatih Puri Village with Pakraman Peguyangan Village. This research will discuss 2 (two) main points, namely: (1) How is the settlement of customary disputes regarding the boundaries between Pakraman Penatih Puri Village and Pakraman Peguyangan Village? (2) What are the factors that hinder the settlement of customary disputes regarding the boundary between Pakraman Penatih Puri and Pakraman Peguyangan villages? This type of research is qualitative research that is descriptive and analytical in nature. Settlement of customary disputes regarding the boundaries between Pakraman Penatih Puri Village and Pakraman Peguyangan Village which are resolved by means of mediation by making a collective agreement or pararem which is used as the legal basis in the Pakraman village. Awig-awig is made in order to create harmony and security in society.
Efektivitas Undang-Undang Nomor 24 Tahun 2007 Tentang Penanggulangan Bencana dan Fikih Kebencanaan Terhadap Perilaku Warga Muhammadiyah (Studi Kasus Covid-19)
Authors: Isngadi Isngadi , Khakim Mufti
Published: February 2021

Disaster management is the obligation of the state in carrying out constitutional duties, namely protecting all spilled Indonesian blood. Disasters have the potential to cause casualties and property. Laws are needed as the basis for government decision making in disaster management. The effectiveness of implementing law number 24 of 2007 can be a benchmark for disaster management. The participation of civil society such as Muhammadiyah mass organizations is a supporting capacity in disaster management. This research is a normative study of the effectiveness of the law on disaster management and Muhammadiyah disaster management case study of Covid 19. The results of the research show that there are many things that need to be evaluated in the implementation of the implementation of the law.
Covid-19
Authors:   Fondazione Vasculab, Passariello Fausto
Published: February 2021

Updates on Covid-19 pandemic
CAMPUR KODE PADA AKUN INSTAGRAM @DEMAKHARIINI (KAJIAN SOIOLINGUISTIK)
Authors: Septiani Dwi , Manasikana Arina
Published: February 2021

Penelitian ini bertujuan untuk mendeskripsikan jenis-jenis dan bentuk-bentuk campur kode pada akun Instagram @demakhariini yang jenis penelitiannya adalah deskriptif kualitatif. Data dalam penelitian ini berjumlah 88 data yang mengandung unsur campur kode di dalamnya. Data-data tersebut diperoleh dari caption atau keterangan pada unggahan foto dan video di akun Instagram @demakhariini. Pada penelitian ini ditemukan tiga jenis campur kode, yaitu jenis campur kode ke dalam, jenis campur kode ke luar dan jenis campur kode campuran. Hasil dari penelitian ini, jenis campur kode dominan adalah jenis campur kode ke luar, yaitu berjumlah 51 data atau 58%, sedangkan jenis campur kode campur kode ke dalam berjumlah 21 data atau 24%, dan jenis campur kode campuran berjumlah 16 data atau 18%.  Kata kunci: Sosiolinguistik, campur kode, Instagram, @demakharini
UPAYA PELESTARIAN KESENIAN KHAS DESA MEKARSARI DAN DESA SIMPANG, KECAMATAN CIKAJANG, KABUPATEN GARUT
Authors: - Soemantri, S. Ypsi , Indira Dian , - Indrayani, L.M.
Published: February 2021

Kesenian khas daerah Sunda merupakan salah satukekayaan budaya yang ada di Jawa Barat. Denganadanya globalisasi, kebudayaan dan kesenian Sundasedikit demi sedikit mengalami pergeseran, Kepunahansuatu kesenian lokal sebagai aset budaya daerahdapat terjadi apabila dalam masyarakatnya terutamagenerasi muda kurang peduli dan tidak memilikikeinginan untuk meneruskan dan mengembangkanserta melestarikan keberadaan seni tradisional tersebut.Berdasarkan kondisi tersebut, perlu dilakukan upayaupayasupaya kesenian khas dapat dipertahankaneksistensi dan kelestariannya sebagai aset budayalokal setempat. Oleh karena itu, melalui kegiatanPengabdian Kepada Masyarakat Integratif ini, kamimelakukan inventarisasi kesenian khas apa saja yangada di Desa Mekarsari dan Desa Simpang KecamatanCikajang, Kabupaten Garut dan upaya-upaya apa sajayang sudah dan perlu dilakukan agar seni dan budayayang ada tidak punah atau tergeser oleh budaya barat.Dengan dilaksanakannya PKM-Integratif “UpayaPelestarian Kesenian Khas Di Desa Mekarsari dan DesaSimpang Kecamatan Cikajang, Kabupaten Garut”diharapkan dapat memotivasi generasi muda setempatuntuk dapat lebih menghargai dan mencintai keseniankhas daerahnya sebagai warisan budaya Sunda yangharus dijaga dan dilestarikan.Kata kunci: kesenian khas, aset budaya, Sunda,pelestarian
PEMANFAATAN TEKNOLOGI INFORMASI DAN KOMUNIKASI DALAM PEMBELAJARAN BAGI PARA GURU SMPN 2 KAWALI DESA CITEUREUP KABUPATEN CIAMIS
Authors: - Budiana, H.R. , - Sjafirah, N.A. , - Bakti, I.
Published: February 2021

Pengembangan dan penggunaan Teknologi Informasidan komunikasi (TIK) dalam pendidikan dapat membuatreformasi untuk sistem pendidikan yang lebih baik.Ketika survei pertama di SMP (SMP) Negeri 2 Kawali,guru menghadapi beberapa kesulitan dalam menerapkan(ICT) dalam proses belajar mengajar di sekolah,karena tidak adanya infrastruktur seperti laboratoriumkomputer, jaringan internet, serta penguasaan TIK dariguru. Program pelayanan masyarakat seperti pelatihanICT untuk guru di SMPN 2 Kawali, Desa Citereupdengan memberikan pengetahuan dan penggunaan ICTdalam proses pembelajaran. Metode yang digunakanadalah: ceramah, diskusi, dan praktek / pelatihan.Aplikasi mereka ditawarkan adalah flash, e-learning,pembelajaran sistem manajemen hanya merupakanpengantar saja dan lebih dalam di Microsoft Word.Setelah menghadiri acara pelatihan ini, guru memilikipengetahuan dan pemahaman tentang keragamanaplikasi ICT. Selain itu, motivasi besar bangkit dariguru untuk dapat mengontrol dan mengoptimalkanpenggunaan ICT untuk mengajar dan belajar di kelas.
PEMANFAATAN LAHAN PEKARANGAN DENGAN MENERAPKAN KONSEP KAWASAN RUMAH PANGAN LESTARI
Authors: Dwiratna Sophia , Widyasanti Asri , Rahmah Devi M
Published: February 2021

Permasalahan yang dihadapi oleh masyarakat Desa Rawa dan Desa Lumbungsari Kecamatan Lumbung Kabupaten Ciamis dalam mengembangkan konsep Kawasan Rumah Pangan Lestari melalui pemanfaatan lahan pekarangan adalah kurangnya pengetahuan dan pelatihan mengenai penyiapan media tanam dalam pot, penyediaan pupuk organik dan pot atau wadah tanaman dari bahan sekitar. Tujuan dari program  pengabdian masyarakat ini adalah (1) Meningkatkan pengetahuan dan ketrampilan, kesadaran serta memotivasi masyarakat khususnya kelompok ibu-ibu rumah tangga dalam pemanfaatan lahan kosong/pekarangan sebagai sumber pangan/ketahanan pangan dan pendapatan keluarga; (2) Menerapkan beberapa teknik sederhana penanaman lahan pekarangan dan pemeliharaannya yang dapat diimplementasikan secara mudah oleh masyarakat.Metode  kegiatan  yang  dilakukan  adalah  penyuluhan,  diskusi  dan demonstrasi  praktek  langsung  di  lapangan  yang  didasari  oleh evaluasi  awal  sebagai  landasan untuk menentukan posisi pengetahuan kelompok sasaran mengenai pemanfaatan lahan pekarangan melalui penerapan konsep Kawasan Rumah Pangan Lestari.Dari hasil kegiatan yang telah dilakukan dapat ditarik kesimpulan bahwa : (1) Pada dasarnya warga masyarakat khususnya ibu-ibu rumah tangga di Desa Rawa dan Desa Lumbungsari telah menerapkan pemanfaatan lahan pekarangan, sehingga kegiatan pengabdian difokuskan pada peningkatan ketrampilan ibu-ibu dalam menyiapkan media tanam untuk budidaya sayuran dalam pot, serta pemanfaatan bahan-bahan sekitar untuk pembuatan pot/wadah dan pupuk organik cair; (2) Kegiatan pengabdian ini dapat menambah pengetahuan warga tentang pentingnya pemanfaatan lahan pekarangan melalui penerapan konsep rumah pangan lestari untuk mendukung ketahanan pangan keluarga.
Conocimientos doblemente libres en la expansión sistémica de la propiedad intelectual
Authors: Isoglio Antonela
Published: February 2021

Los conocimientos doblemente libres se caracterizan por circular con restricciones mínimas de uso, pero también porque su aprovechamiento está exento de remunerar a sus productores. Este trabajo busca comprender los flujos de conocimientos que adoptaron este carácter en la década de 1980, a partir del estudio de caso. Las unidades de análisis son los proyectos GNU, Perl y GenBank. En sus configuraciones materiales cognitivas, hallamos conocimientos objetivos, subjetivos, intersubjetivos y biológicos, que se concretizaron en bienes informacionales regulados por licencias de derechos de autor o el dominio público.
“CONSTANT, ZIG-ZAG LINEAR, OR MULTIPLE?”: THEMATIC PROGRESSION PATTERNS ON EFL STUDENTS’ RECOUNT TEXTS
Authors: Devira Merina , Makhroji Makhroji , Syahputra Bania Allif , Sari Novia
Published: February 2021

The main problem faced by EFL students in writing English texts includes the difficulties to produce a cohesive and coherent text that it seems necessary to show how the tools of Theme and Rheme can be used to help construct the students' good English writing. This study aimed to find out the types of thematic progression patterns in each clause of the recount texts written by students and the dominant pattern of thematic progression revealed from the texts. The research design of this study is a qualitative method which employed the study instrument of the students' recount texts at class IX of SMAN 2 Langsa, Aceh. A content analysis approach by using a Theme and Rheme framework generated from a theory of Systemic Functional Linguistics (SFL) was used to analyze the thematic progression patterns on the students' recount texts, which included several steps: reading the student's texts, identifying the theme and rheme of every clause of the student's text, describing the thematic progression patterns of student's text and drawing the thematic progression pattern on student's text. The findings of the analysis indicated that there are three (3) thematic progression patterns found on the students' recount texts: the Theme Constant, the Theme Zig Zag Linear pattern and Theme Multiple patterns. The dominant type of thematic progression patterns constructed by the students into their recount texts was revealed mostly on 123 constant or reiteration patterns (76.8%), followed by zig-zag patterns of 35 times (21.8%)  and 9 times (1.25%) of multiple patterns. The results of this study will be facilitative as the tools for English language teaching and learning classrooms particularly for writing English texts.
Pengaruh Spiritualitas terhadap Subjective Well Being Mahasiswa Tingkat Akhir
Authors: Arung Nancy Lolo , Aditya Yonathan
Published: February 2021

Mahasiswa tingkat akhir yang sedang mengerjakan tugas akhir sebagai syarat kelulusan, banyak mengalami tekanan yang mengakibatkan munculnya stres dan depresi. Timbulnya stres dan depresi dalam diri mahasiswa dapat mengakibatkan rendahnya subjective well being sehingga dapat memengaruhi performa pengerjaan tugas akhir. Spiritualitas dianggap dapat memengaruhi tingkat subjective well being mahasiswa, karena dengan spiritualitas individu dapat merasakan kehadiran Tuhan dan mendapatkan social support saat dalam masa sulit. Oleh karena itu, penelitian dilakukan dengan tujuan untuk mengetahui pengaruh spiritualitas terhadap subjective well being mahasiswa. Penelitian dilakukan menggunakan metode kuantitatif, dan menggunakan teknik purposive sampling yang dilakukan pada 150 mahasiswa tingkat akhir. Alat ukur yang digunakan dalam penelitian ini adalah SHALOM (α=.91), SPANE  (α=.87, α=.78) dan SWLS (α=.82). Hasil penelitian menunjukkan adanya pengaruh yang signifikan antara spiritualitas terhadap subjective well being (β = .22, p < .05), yang berarti semakin tinggi spiritualitas mahasiswa maka semakin tinggi pula tingkat subjective well being mahasiswa tersebut.
Un sistema de empleo público distópico: ¿sería preciso reformar el EBEP?
Authors: Castillo Blanco Federico Amador
Published: February 2021

El presente trabajo analiza, atendiendo a la experiencia acumulada en los distintos ciclos de reforma del empleo público y las exigencias que actualmente tienen planteadas las Administraciones públicas, las distintas vertientes en que sería adecuado proceder a reformar el sistema de empleo público español explorando distintas soluciones a fin de enfrentar ese desafío que, como se concluye, no es meramente normativo e implica distintas acciones en la economía política de ese hipotético proceso.
Los Claroscuros del EBEP en los procedimientos de concurrencia competitiva: reflexiones empíricas y propuestas innovadoras
Authors: Fondevila Antolín Jorge
Published: February 2021

Este trabajo se ha concebido como una breve reflexión de la actual situación del empleo público, con relación a los procedimientos de concurrencia competitiva, en concreto, se examina el vigente marco legal básico (TREBEP), sus aportaciones, deficiencias y, en especial, se formulan algunas propuestas de reforma del mismo, con relación a los procedimientos selectivos para el acceso al empleo público, así, como también sobre el desarrollo de los procedimientos de provisión de puestos de trabajo, elemento este último clave en el desarrollo de la carrera administrativa de los funcionarios.
Greedy, A-Star, and Dijkstra’s Algorithms in Finding Shortest Path
Authors: Wayahdi Muhammad Rhifky , Ginting Subhan Hafiz Nanda , Syahputra Dinur
Published: February 2021

The problem of finding the shortest path from a path or graph has been quite widely discussed. There are also many algorithms that are the solution to this problem. The purpose of this study is to analyze the Greedy, A-Star, and Dijkstra algorithms in the process of finding the shortest path. The author wants to compare the effectiveness of the three algorithms in the process of finding the shortest path in a path or graph. From the results of the research conducted, the author can conclude that the Greedy, A-Star, and Dijkstra algorithms can be a solution in determining the shortest path in a path or graph with different results. The Greedy algorithm is fast in finding solutions but tends not to find the optimal solution. While the A-Star algorithm tends to be better than the Greedy algorithm, but the path or graph must have complex data. Meanwhile, Dijkstra's algorithm in this case is better than the other two algorithms because it always gets optimal results.
DESIGN AND REALIZATION OF GRIPPERS WITH PERMANENT MAGNETS
Authors: Tuleja Peter
Published: February 2021

Urgency of the research. Modern production requires simple and inexpensive component solutions for gripping large parts. The design of gripping elements using a permanent magnet in this aspect is a promising direction. Target setting. The aim of the project was to realize a gripping component from a commercially available pneumatic
drive supplemented with a neodymium permanent magnet and to revive the resulting assembly with a pneumatic portal manipulation device designed for educational activities at the department. Actual scientific researches and issues analysis. Implementation of the project required a detailed market research focused
on the tentacles of a similar concept and the study of the principles and properties of permanent magnets. By analyzing the information the project objective was optimized - design of cheap and reliable gripping element. Uninvestigated parts of general matters defining. Available components were used for the resulting solution, with an emphasis on low acquisition costs. This was due to the fact that the output was intended for laboratory use. The research objective. The aim of the research was to build a real functioning and reliably working gripping device usable as an object for educational activities in the education of our students. The statement of basic materials. Design and practical implementation of the grippers with permanent magnets for gripping
parts represented in the work. Activation and control of the grips is implemented by compressed air. The implementation of the output confirmed the correctness of considerations as well as the feasibility of the repeatability of this output while meeting the basic requirement for low costs. The project was based on the principles offered by leading companies, but the implementation output gives a higher gripping force at lower input costs. In addition, it provides the possibility of extension to the size range
according to customer requirements. Conclusions. The project was successful and its implementation also contributed to the improvement of the educational
process at the department, which was one of the monitored benefits. It provides an illustrative demonstration of the possibilities of performing manipulation tasks with non-standard objects.
Clinical case of Bloch — Sulzberger syndrome
Authors: Krasnova Nadezhda V. , Chernova Tatyana A. , Alekseeva Irina V. , Gimalieva Geliya G. , Misyakova Tatiana , Sinitsyna Larisa G.
Published: February 2021

Purpose.To present a clinical case of Bloch Sulzberger syndrome.

Material and methods. The examinations were performed to diagnose the disease: а visual examination of the skin, cytological analysis of the gallbladder fluid, general and biochemical blood tests, genetic research.

Results.During a visual examination of the skin, a differential diagnosis was made with infectious dermatitis, toxic-allergic dermatitis, epidermolysis bullosa and linear IgA-dependent dermatosis in children. Crucial in the diagnosis belonged to a genetic study, after which a deletion of exons 410 of the IKBKG gene was detected, which confirmed Bloch Sulzberger syndrome.

Conclusion.Newborns with vesicle-bullous rashes entering the neonatal pathology department and observed by neonatologists require a thorough examination, a mandatory consultation of a dermatologist inorder to determine further management tactics.
Treatment of сongenital melanocytic nevus in infants and children by a dual-wavelengths copper vapor laser
Authors: Ponomarev Igor V. , Topchy Sergei B. , Pushkareva Alexandra E. , Andrusenko Yury N. , Shakina Ludmila D.
Published: February 2021

Introduction.Congenital melanocytic nevus (CMN) is detected at birth or shortly after birth in 1% of infants. The localization of CMN in aesthetically significant areas causes a decline in child self-esteem and causes concern for his parents. Surgical excision of skin areas with CMN is associated with an increased risk of cosmetic side effects and is often followed by long-term stress conditions after the invasive intervention.
Aim of the study.To evaluate the efficacy of the CMN removal in infants, children and adolescents with the dual-wavelengths copper vapor laser (CVL) radiation.
Patients and Methods.Medium-sized (up to 9 cm) single CMN was treated in nine fair-skinned patients: seven girls and two boys, aged from 2 months to 16 years. The procedures were carried out at an average CVL power of 0.61.0 W, with a power ratio of 3:2 at 511 nm and 578 nm wavelengths, and an exposure time of 0.20.3 s. Light spot diameter 1 mm. The treatment was carried out during 210 sessions with an interval of 12 months between sessions.
Results.In children and adolescents, the treatment of CMN with CVL dual-wavelengths radiation made it possible to achieve significant clarification of the involved area without hypertrophic scars. The duration of the healing of the irradiated area lasted 23 weeks. Side effects were manifested with subtle skin atrophy.
Conclusion.The high efficacy of CVL removal of medium-sized CMN in infants and children using the dual-wavelengths CVL radiation without pronounced side effects allows introducing such an approach in the clinical practice of pediatric dermatologists and cosmetologists.
New technologies in topical acne therapy
Authors: Samtsov Alexey V.
Published: February 2021

The article is of an overview nature, it outlines the current understanding of the pathophysiology of acne, provides data on the role of retinoids in the treatment of dermatosis, discusses the advantages of combination therapy and new technologies in the treatment of acne.
Dermatoses among patients aged 60 years and above attending a tertiary referral center: A cross-sectional study from North Kerala
Authors: Simin Muhammed Kutty , Sasidharanpillai Sarita , Rajan Uma , Riyaz Najeeba
Published: February 2021

Objectives:

With the rise in life expectancy at birth, geriatric population contributes to a significant proportion of those seeking medical aid. Skin problems in the elderly are very common and vary according to region and ethnicity. It is essential for dermatologists to have a better understanding of the pathophysiology of geriatric skin disorders to formulate quality management guidelines. This study was undertaken to document the frequency and the clinical pattern of various physiological and pathological changes in the elderly skin.

Materials and Methods:

A cross-sectional study was carried out in 200 consecutive patients aged 60 years and above and who attended the Dermatology outpatient clinic of a tertiary referral center in North Kerala. A pre-set pro forma was used to document the patient characteristics, the comorbidities, the medications used, and the clinical findings.

Results:

All the study participants (100%) had one or more dermatoses. The age of the study population ranged from 60 to 89 years (mean 67.7 ± 6.2 years). This was a female preponderant study with a female to male ratio of 1.4:1. Hypertension (36%), hyperlipidemia (27%) and diabetes mellitus (26%) were the common comorbidities observed. Graying of hair was the most common physiological change, followed by wrinkling. Pruritus was the most common presenting complaint (136, 68%). Statistically significant association was noted between xerosis and generalized pruritus. Fungal infections (30.5%) outnumbered other infections and infestations. Changes of severe photoaging were less frequent. One patient had skin malignancy (basal cell carcinoma). Significant association was noted between photoaging and male sex, smoking, and sun exposure.

Limitations:

Study conducted in a tertiary referral center not reflecting the status in the community was the major limitation.

Conclusion:

Photoaging and skin cancers are less frequent in darker skin type. Healthy lifestyle, nutritious diet, frequent application of emollient, better skin care, and judicious use of sunscreen can delay the process of cutaneous aging. More prospective studies in different population groups may go a long way in improving the current knowledge about the less known aspects of geriatric dermatoses.
Reoperation for recurrent glioblastomas: What to expect?
Authors: Neville Iuri Santana , Santos Alexandra Gomes dos , Almeida Cesar Cimonari , Abaurre Leonardo Bilich , Wayhs Samia Yasin , Feher Olavo , Teixeira Manoel Jacobsen , Lepski Guilherme
Published: February 2021

Background:

The current standard treatment for glioblastoma (GBM) is maximal safe surgical resection followed by radiation and chemotherapy. Unfortunately, the disease will invariably recur even with the best treatment. Although the literature suggests some advantages in reoperating patients harboring GBM, controversy remains. Here, we asked whether reoperation is an efficacious treatment strategy for GBM, and under which circumstances, it confers a better prognosis.

Methods:

We retrospectively reviewed 286 consecutive cases of newly diagnosed GBM in a single university hospital from 2008 to 2015. We evaluated clinical and epidemiological parameters possibly influencing overall survival (OS) by multivariate Cox regression analysis. OS was calculated using the Kaplan–Meier method in patients submitted to one or two surgical procedures. Finally, the survival curves were fitted with the Weibull model, and survival rates at 6, 12, and 24 months were estimated.

Results:

The reoperated group survived significantly longer (n = 63, OS = 20.0 ± 2.3 vs. 11.4 ± 1.0 months, P < 0.0001). Second, the multivariate analysis revealed an association between survival and number of surgeries, initial Karnofsky Performance Status, and age (all P < 0.001). Survival estimates according to the Weibull regression model revealed higher survival probabilities for reoperation compared with one operation at 6 months (83.74 ± 3.42 vs. 63.56 ± 3.59, respectively), 12 months (64.00 ± 4.85 vs. 37.53 ± 3.52), and 24 months (32.53 ± 4.78 vs. 12.02 ± 2.36).

Conclusion:

Our data support the indication of reoperation for GBM, especially for younger patients with good functional status. Under these circumstances, survival can be doubled at 12 and 24 months.
Abordaje mínimamente invasivo para el tratamiento de tumores espinales intradurales extramedulares: Nota Técnica
Authors: Landriel Federico , Hem Santiago , Vecchi Eduardo , Yampolsky Claudio
Published: February 2021

Objetivo:

Describir la técnica de abordaje mínimamente invasiva para el tratamiento de tumores intradurales extramedulares en los diferentes segmentos espinales.

Material y Métodos:

Se detallan la planificación, posicionamiento, marcación, pasos técnicos del abordaje mínimamente invasivo, exéresis lesional y cierre de lesiones ID-EM a nivel cervical, dorsal, lumbar y sacro. Se proporcionan recomendaciones para descomplejizar maniobras quirúrgicas, acortar el tiempo operativo y evitar potenciales complicaciones.

Conclusiones:

El abordaje MISS es una opción segura y eficaz para el tratamiento quirúrgico de determinados tumores ID-EM.
Review of laminoplasty versus laminectomy in the surgical management of cervical spondylotic myelopathy
Authors: Paracino Riccardo , Fasinella Maria Rossella , Mancini Fabrizio , Marini Alessandra , Dobran Mauro
Published: February 2021

Background:

We reviewed the literature comparing the indications/efficacy of laminectomy (LA) with or without fusion versus laminoplasty (LP) in the treatment of cervical spondylotic myelopathy (CSM).

Methods:

We identified 14 studies in PubMed/Medline to include in our analysis. Outcomes were assessed utilizing the Japanese Orthopaedic Association (JOA) score, visual analog scale (VAS), Neck Disability Index, and Nurick scale. Variables studied included ossification of the posterior longitudinal ligament (OPLL), cervical range of motion (ROM), the C2-C7 sagittal Cobb angle, the Ishihara index, and the Hirabayashi scale. Patients with cervical trauma/fracture, infection, or tumor were excluded from the study.

Results:

In these 14 studies, there were no significant differences between LA and LP groups in terms of preoperative versus postoperative: JOA scores (e.g., including the improvement rate), VAS scores, and ROM. However, the LA patients demonstrated greater postoperative cervical lordosis versus those in the LP group.

Conclusion:

At present, there are no guidelines for choosing LA versus LP for treating CSM. Factors that should be considered when choosing one procedure over the other should include the patients’ preoperative clinical status, the type of CSM, the pathological extent of OPLL, and whether there is a sufficient cervical lordotic curvature.
Anterior cervical spine surgical complications: Safety comparison between teacher and student
Authors: Zekaj Edvin , Iess Guglielmo , Servello Domenico
Published: February 2021

Background:

Anterior cervical surgery has a widespread use. Despite its popularity, this surgery can lead to serious and life-threatening complications, and warrants the attention of skilled attending spinal surgeons with many years of experience.

Methods:

We retrospectively evaluated postoperative complications occurring in 110 patients who underwent anterior cervical surgery (anterior cervical discectomy without fusion, anterior cervical discectomy and fusion, and anterior cervical disc arthroplasty) between 2013 and 2020. These operations were performed by an either an attending surgeon with 30 years’ experience versus a novice neurosurgeon (NN) with <5 years of training with the former surgeon. Complications were variously identified utilizing admission/discharge notes, surgical reports, follow-up visits, and phone calls. Complications for the two groups were compared for total and specific complication rates (using the Pearson’s Chi-square and Fisher’s test).

Results:

The total cumulative complication rate was 15.4% and was not significantly different between the two cohorts. The most frequent postoperative complication was dysphagia. Notably, there were no significant differences in total number of postoperative instances of dysphagia, dysphonia, unintended durotomy, hypoasthenia, and hypoesthesia; the only difference was the longer operative times for NNs.

Conclusion:

Surgeons’ years of experience proved not to be a critical factor in determining complication rates following anterior cervical surgery.
Analysis of The Professional Anxieties of The Intern Physicians Attending The Internship Program For Emergency Medical Service (An Example From Çanakkale Onsekiz Mart University)
Authors: AKMAN Canan , AYTUĞ KOŞAN Ayşen Melek , TORAMAN Çetin , AKDUR Gökhan , AKDUR Okhan
Published: February 2021

Purpose: The purpose of this present study is to compare the professional anxieties of the intern physicians who attend the internship program for emergency medical service in the pre- and post-internship period and to explore whether the internship experience for emergency medical service leads to a change in their professional anxieties.Materials and Method: Based on observation, this study was performed with 83 intern physicians at a single medical school in Turkey. The professional anxieties of interns in this study were determined based on the Occupational Anxiety Scale of Emergency Health Professionals. Data were analyzed through the paired samples t-test. Findings: The least anxiety-provoking triggers for the intern physicians in the pre-internship period are as follows: “Not being able to do my profession efficiently as I get older due to the fact that it requires physical activity”, “Risk of being disabled while providing the service”, “Decreased income in case of disability”, “Lack of knowledge and skills among my colleagues”, “Obstacles for transferring patients (narrow aisle, etc.)”, “Unergonomic intervention and transfer equipment.” These triggers were also the least anxiety-provoking triggers in the post-internship period. The most anxiety-provoking triggers for the intern physicians in the pre-internship period are as follows: “Possibility of suffering from physical violence while providing the service”, “Possibility of suffering from verbal violence while providing the service”, “Lack of staff”, “Unethical behaviors that can be encountered while providing the service” and “Patients’ and patient relatives’ prejudice against us.” It is remarkable that these anxieties did not show a downward trend even in the post-internship period.Conclusion: The study concluded that the internship program for emergency medical service attended by the intern physicians did not lead to any change in their anxieties. Further studies may compare the internship program for emergency medical service that intern physicians in other universities take part in and the program in this study in terms of its effect on the concerns of the students. Moreover, it is necessary to review the internship program for emergency medical service for intern physicians and examine its effectiveness. Lastly, the concerns of intern physicians about emergency response can be explored through qualitative research.
MENINGKATKAN MINAT BELAJAR SEJARAH MELALUI MODEL LISTENING TEAM PADA SISWA KELAS X MADRASAH ALIYAH
Authors: Trisnawati Trisnawati
Published: February 2021

Penelitian ini bertujuan untuk menganalisis pengaruh penggunaan model pembelajaran listening team terhadap hasil belajar siswa pada mata pelajaran sejarah kelas X Madrasah Aliyah Darul Ulum Kuala Dua kecamatan Kubu Raya. Metode yang digunakan dalam penelitian ini adalah quasi eksperimental design type nonequivalent control group design. Berdasarkan hasil penelitian diperoleh rata-rata hasil post test kelas kontrol 66,32 dan rata-rata hasil post test kelas eksperimen 78,09 diperoleh thitung 5,8037 dan ttabel (α = 5%). sebesar 1,6809 yang berarti thitung> ttabel, maka Ha diterima. Pada perhitungan effect size (ES) diperoleh 1,41 (kriteria tinggi). Artinya model pembelajaran tim menyimak yang digunakan memiliki pengaruh yang tinggi terhadap hasil belajar siswa kelas X Madrasah Aliyah Darul Ulum Kuala Dua Kecamatan Kubu Raya.

Kata kunci: Efek, Model Tim Mendengarkan, Hasil Belajar
Macroscale Superlubricity and Polymorphism of Long-Chain n-Alcohols
Authors: Reddyhoff Tom , Ewen James , Deshpande Pushkar , Frogley Mark , Welch Mark D. , Montgomery Wren
Published: February 2021

Simple n-alcohols, such as 1-dodecanol, show anomalous film-forming and friction behaviour under elastohydrodynamic lubrication (EHL) conditions, as found inside bearings and gears. Using tribometer, diamond anvil cell (DAC), and differential scanning calorimetry (DSC) experiments, we show that liquid 1-dodecanol undergoes pressure-induced solidification when entrained into EHL contacts. Different solid polymorphs are formed inside the contact depending on the temperature and pressure conditions. Surprisingly, at moderate temperature and pressure, 1-dodecanol forms a polymorph that exhibits robust macroscale superlubricity. The DAC and DSC experiments show that superlubricity is facilitated by the formation of lamellar, hydrogen-bonded structures of hexagonally close-packed molecules, which promote interlayer sliding. This novel superlubricity mechanism is similar to that proposed for the two-dimensional materials commonly employed as solid lubricants, but it also enables the practical advantages of liquid lubricants to be maintained. When the pressure is increased, 1-dodecanol undergoes a polymorphic transformation into a phase that gives higher friction. The DAC and DSC experiments indicate that the high-friction polymorph is an orthorhombic crystal. The polymorphic transformation pressure coincides with the onset of dimple formation in the EHL films, revealing that the anomalous film shapes are caused by the formation of rigid orthorhombic crystals inside the contact. This is the first demonstration of macroscale superlubricity in an EHL contact lubricated by a non-aqueous liquid that arises from bulk effects rather than tribochemical transformations at the surfaces. Since the superlubricity observed here results from phase transformations, it is continuously self-replenishing and is insensitive to surface chemistry and topology. This discovery creates the possibility of implementing superlubricity in a wide range of machine components, which would result in enormous improvements in efficiency and durability.
Local, Single-Molecule Oxidative Cleaving of DNA Origami by C60 on an AFM Tip
Authors: Ray Ankita , Passiu Cristiana , Ramakrishna S.N , Rossi Antonella , Kuzuya Akinori , Spencer Nicholas D. , Yamakoshi Yoko
Published: February 2021

Spatially controlled single-molecule oxidation of DNA was performed by photocatalytic generation of singlet oxygen on chemically functionalized AFM tips. A waffle-type DNA origami deposited on a mica surface is site-specifically destroyed by generation of reactive oxygen species at the AFM tip, which was modified with C60-tripod photocatalyst. Upon AFM scanning under photoirradiation, DNA morphology changes, corresponding to oxidative damage were clearly observed at the single-molecule level. The DNA cleavage occurred with strict dependence on photoirradiation and the presence of C60 on the AFM tip.
Prebiotic Photoredox Synthesis from Carbon Dioxide and Sulfite
Authors: Liu Ziwei , Wu Long-Fei , Kufner Corinna , Sasselov Dimitar D. , Fischer Woodward , Sutherland John
Published: February 2021

Carbon dioxide (CO2) is the major carbonaceous component of many planetary atmospheres including the Earth throughout its history, and prebiological chemistry that reduces this C1 feedstock to organics has accordingly been sought. Carbon fixation chemistry utilizing hydrogen as stoichiometric reductant tends to require high pressures and temperatures, and yields of products of potential use to nascent biology are low1 . Here we demonstrate efficient ultraviolet (UV) photoredox chemistry between CO2 and sulfite (SO3 2–) that generates organics and sulfate (SO4 2– ). The chemistry is initiated by electron photodetachment from SO3 2– giving sulfite radicals and hydrated electrons, which reduce CO2 to its radical anion. By subjecting individual products and putative intermediates to the reaction conditions and analyzing the resultant mixtures, a network of ensuing reactions that can rationalize the products was revealed. In this way it was further discovered that citrate, malate, succinate, and tartrate can be generated by irradiation of glycolate in the presence of SO3 2– . The simplicity of this carboxysulfitic chemistry and the widespread occurrence and abundance of its feedstocks suggest that it could have readily taken place on the early Earth as well as on the surfaces of many rocky planets. The environmental availability of the carboxylate products on Earth could have driven the development of central carbon metabolism before the advent of biological CO2 fixation.