bluuebunny/crossref_metadata_2025 huggingface dataset:
Economic and Environmental Impact of Poultry Production in Ilorin Metropolis, Kwara State, Nigeria
Authors:   Department of Agricultural Economics, Ladoke Akintola University of Technology, Ogbomoso, Nigeria., A Henri Ukoha, ,   Department of Agricultural Economics and Agribusiness Management, University of Port Harcourt, Port Harcourt, Nigeria., Adekunle Ismaila Yusuf ,   Department of Agricultural Economics and Farm Management University of Ilorin, Nigeria
Published: July 2023

This study investigated the economic and environmental impact of poultry production in Ilorin, Kwara State. Primary data were used and a sample of 120 poultry farmers through a multistage sampling technique was drawn from the study. The data collected were analysed using descriptive statistics, gross margin analysis, OLS regression model and Likert-type scale. The results show that the enterprise incurred an average total variable cost of N135,450.0 and total revenue within the period was estimated to be N192,323.80 which was mainly generated from the sales of poultry birds. The gross margin was found to be N56,873.8 with N0.4199 can be obtained with a unit increase in the poultry production capacity. Thus, the broiler production is a profitable venture in the study area. The empirical finding based on the regression result indicate that, cost of labour, cost of chicks and marital status had positive coefficient and statistically significant in influencing the total revenue level. It means that any increase in their value will increase the revenue level. The result of vaccine/medication administered against diseases revealed that most of the poultry farmers uses Lasota vaccine (88%) against Newcastle disease, a combination of amprolium and coccimapro (27%) each for Coccidiosis, pox off (88%) for fowl pox disease, Gumboro vaccine (65%) for IBD gumboro and their sources of getting the medication/vaccines are majorly from Aromokeye agro vet and One step pharmacy. The analysis shows that among the various ways of waste management, the farmers uses the waste more for fertilizer (28%) followed by selling them (23%) while only (21%) of the farmers burn the waste (especially the dead birds) so as to prevent further spread of diseases on the farm. The empirical findings based on the environmental impact of poultry production reveals that waste generation is the major negative environmental impact of poultry production in the study area. Offensive odour also associated with poor waste management is ranked 2nd, diseases transmission, air pollution and water pollution are among the environmental impact of poultry production in the study area. Poor management system is perceived to be the major constraint, lack of security and government support ranked 2nd is seen as a problem.
Evaluation of Water Quality within and around Flood Prone area and Dumpsite Environment in Part of Benin Metropolitan city Southern, Nigeria
Authors:   Department of Geology, University of Benin, Benin City., Aladin Ese Anthony , E.E Okoroafor, ,   Department of Geology, University of Benin, Benin City.
Published: July 2023

The study was carried out in Egor local government area, Dumpsite in Ovia North-East local government area of Edo state. The study areas are located between latitudes of 6°27'27.8''N to 6°27'44.6''N and longitudes of 5°35'58.7″E to 5°36'16.8''E in Egor local government area and the dumpsite is located with a latitude of 6°22´1.2''N to 6°27´51.3″N and longitudes of 5°36'42.3''E to 5°36´2.1″E in Ovia North-East local government area. A total of five (5) water samples were collected from an existing borehole at different locations within the study area. Physiochemical test, Major anion and cation concentration was determined using Atomic Absorption Spectrophotometer (AAS). Microbiological Parameters for all the water samples was also determined. The following are the physiochemical parameters, major cations and anions that was analysed from all the water samples collected: pH, EC, TDS, Na+, Ca+, Mg2+, Cl-, NO3- , HNO3- , HNO3- , SO42- , Cr2-, Cd-, Ni-, and Pb2+ and the Microbiological parameter analysed for all the water samples are Coliform and E. Coli. The Microbiological parameter analysed for are Coliform and E. Coli as shown in Table 1. The results reveals that the study areas have average value of pH (4.89) which is below the WHO (2011) and NSQW (2007) standard permissible limit of 6.5-8.5 and this indicates that the water is slightly acidic probably due to the presence of decayed organic matter in high amounts and mineral acids produced during hydrolysis. The average values of E.C (121.86μS/cm), TDS (46.52mg/l), Na+ (1.48mg/l), Cl- (53.85mg/l), NO3- (1.17mg/l), HNO3- (0.39mg/l), SO42- (0.12mg/l), Cr2- (0.031), and Ni- (0.0074) conforms with the WHO (2011) and NSQW (2007) standard for drinking water expect some physiochemical parameters : Ca2+, Mg2+ Cd-, Pb2+, E.Coli and Coliform which has average values (4.49mg/l, 3.10mg/l, 0.027mg/l, 0.016mg/l, 1.36 X 103 (cfu/100mL)and 1.06 X 103 (cfu/mL) which do not conform with the WHO (2011) and NSQW (2007) for drinking water because of many factors and anthropogenic activities on the environment which contaminated the groundwater of the study areas. The results analysed from the three-study area reveals that the physiochemical parameters and microbiological parameters show similar trend. The water sample collected in the premises of University of Benin is more acidic compare to other water samples from the other locations. This probably due to the presence of decayed organic matter in high amounts and mineral acids produced during hydrolysis.
Covid-19 and Iran
Authors:   Institue of Microbiology and Molecular Genetics, University of the Punjab, Lahore.Pakistan., Ali Maida ,   Tertiray Care Hospitals, Lahore. Pakistan.
Published: July 2023

The global pandemic of covid-19 has struck the world and has grasped the attention of all eminent countries of world by debilitating the health as well as economic status of countries. This has shattered the overall population of world as hundreds of people tasted death and millions are still fighting this battle. Among the most affected countries, Iran is the country where this scourge has accumulated every nook and corner. Consequently, Iranian government has faced severe economic crises which has forced the government to seek heavy loan.
Impact of Technology on Organizational Culture and Human Diversity in Pakistan
Authors:   Institute of Microbiology and Molecular Genetics, University of the Punjab Lahore, Pakistan, Riaz Samreen
Published: July 2023

Technology commands our life in a substantial manner. It has totally altered the way we communicate and process the information. Day by day improvements in technology have totally removed the borders that kept people of different areas apart as actually these boundaries don’t occur on the worldwide web. In this period of technology, Internet plays an active part in almost every field of life. Through advanced technology, users can interconnect with each other by using diverse platforms. When technology is solution of one problem it is also on the other hand causes of other problems. The corona virus quarantine, which compelled millions of people to work from home, has also accelerated the use of online communication technologies, resulting in even less human interaction than previously. Cyber bullying is now possible because of technological advancements, and youngsters are especially vulnerable to online harassment. There is a strong bond between organizational culture and technology. Organizational cultural can be defined as the common perception held by the organization’s members in a system of shared meaning. The dominant culture in an organization being the core values that are shared by a majority of the organization’s members. Culture is so essential for a technology organization as it defines the clear-cut boundaries present between one organization and others. In this paper we would like to compare the cultural values of the technology industry to culture values of another industry and we will observe the comparison, the effect of cultural values and the amount of users of different technologies in Pakistan.
Assessment of Mental Imagery of Movement in Schizophrenia
Authors:   Academic scholarship of the Department of Obstetrics, University of Western Macedonia,   PhD Cognitive Psychology, Neuropsychologist of C’ Department Psychiatric Clinic of HEPA Hospital Thessaloniki, George Savvidis ,   PhD candidate, Department of Obstetrics, University of Western Macedonia, Maria Sofologi ,   Cognitive psychologists, Margarita Hanopoulou ,   Cognitive psychologists, Konstantinos Tsagaridis ,   Cognitive psychologists, Grigoris Karakatsoulis ,   Psychiatrist Consultant, 3rd Psychiatry Department of the Aristotle University of Thessaloniki, University General Hospital of Thessaloniki, AHEPA., Konstantinos Fountoulakis ,   Professor, Director of C’ Department Psychiatric Clinic of AHEPA Hospital Thessaloniki, Ioannis Nimatoudis ,   Professor, of C’ Department Psychiatric Clinic of AHEPA Hospital Thessaloniki, Charalampos Papaxanthis ,   Professor, Directeur du laboratoire CAPS (Cognition, Action, et Plasticité Sensorimotrice), Université de Bourgogne, Dijon France.
Published: July 2023

Schizophrenia patients often present with neurological signs such as left/right confusion, impaired coordination of movements, and motor abnormalities may occur secondary to antipsychotic medications. Neuropsychological tests identify various dysfunctions, such as difficulty in focusing attention, difficulty in abstract thinking or difficulty in changing the response frame, while Neurophysiological tests show slowing down of reaction time, problems with eye tracking, etc. There are no studies in the international literature dealing with the investigation of mental imagery of movement in Greek patients with schizophrenia. Also, the position that patients with schizophrenia – regardless of their symptom profile, age, sex, and chronicity of the disease – have a permanent difficulty in creating and manipulating an internal model of their movement prediction, has not been substantiated enough to date. Aim: In the present study we examine the function of visual-motor coordination and the time to achieve the goal-directed movement of the dominant hand of patients with schizophrenia Method: The sample we used in our research consisted of patients with diagnosed schizophrenia and healthy individuals. Schizophrenia patients belonged to the experimental group and healthy subjects to the control group. The number of examined patients was 39 and the healthy 51. the assessment of the movement and its mental representation was carried out with the real and mental movement of the dominant hand between two square targets located at a distance of 20 cm, on white paper of A4 size. Conclusions: Visuomotor coordination of a specific hand movement differs between patients with schizophrenia and the normal population. In particular, the means of the goal-directed hand movement achievement time in the actual execution condition and in the mental execution condition of the patients were significantly higher than the corresponding times of the standard population.
Decreased Thyroid Function in Nasopharyngeal Carcinoma Patients Who Received Chemoradiotherapy in DR Sardjito Public Hospital, Yogyakarta, Indonesia
Authors:   Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, University of Gadjah Mada, Yogyakarta, Indonesia., . Solikin , Indrasari Sagung Rai , Surono Agus , Listiati Afifah ,   Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, University of Gadjah Mada, Yogyakarta, Indonesia.
Published: July 2023

Background: Radiotherapy has long been recognized as the mainstay for the treatment of nasopharyngeal carcinoma with or without chemotherapy. Chemoradiotherapy can induce a transformation of thyroid gland causing thyroid disorder. Objective: This study has evaluated a decrease in thyroid function in patients with nasopharyngeal carcinoma who received chemoradiotherapy. Methods: This is a pre-post study design. The subject includes patients with nasopharyngeal carcinoma that underwent chemoradiotherapy. Patient's thyroid functions were measured twice; before and 3 months after chemoradiotherapy. Results: We observed the result of 30 patients that underwent chemoradiotherapy. The results of pre and post treatment for FT3, FT4 and TSH show p-value of 0,001, 0,0043 and 0,015 respectively showing statistically significant difference between two measurement period. Conclusion: We found an alteration in thyroid function in patients with nasopharyngeal carcinoma who received chemoradiotherapy.
Post-Morther Changes in Rat Paretial Cortic and Hippocampus Neurons. Morphological Characteristics
Authors:   Grodno State Medical University, 80, Gorkogo St., 230009, Grodno, Republic of Belarus, N.E., Maksimovich , S.M., Zimatkin , N.V. Kokhan
Published: July 2023

Target. Analysis of changes in the morphological characteristics of neurons in such phylogenetically different parts of the rat cerebral cortex in different periods after total cerebral ischemia. Methodology. Experiments were performed on 42 male outbred white rats with an initial weight of 240±20 g. Total cerebral ischemia in outbred white rats was modeled by decapitation. The material was taken at the 1st, 5th, 15th, 30th, and 60th minutes, as well as 5 and 24 hours after decapitation. Results. With total cerebral ischemia, a significant decrease in the size of neurons and deformation of the perikarya were observed. Normochromic neurons completely disappeared at the 60th minute. The number of hyperchromic neurons increased and then progressively decreased. Shriveled neurons accounted for the majority of cells in the studied areas of the cortex at 30-60 minutes, and then, after 5 and 24 hours, cells with pericellular edema predominated in the neuron population. Conclusion. The obtained data on histological changes in neurons of phylogenetically different parts of the cerebral cortex in the dynamics of total cerebral ischemia provide the basis for further detailed study of post-mortem changes in the brain, determining the time of death, creating a fundamental basis for studying the properties of neurons, including their transition from one functional state to other.
Peningkatan Keaktifan Siswa Kelas 2C di MI Nurussalam pada Materi Akidah Akhlak Melalui Pendekatan Auditori-Somatis-Visual-Intelektual (ASVI)
Authors: Alinda Zakiyatul Fakhiroh  , Lutfia Zaina
Published: July 2023

Abstract: This study aims to improve student learning activeness by applying the Auditory-Somatic-Visual-Intellectual (ASVI) approach. This research is a Class Action Research conducted in two cycles. Where each cycle consists of planning, implementation, observation, and reflection. Data collection techniques carried out are with and non tests (observation, interviews, and questionnaires). Data analysis used qualitative descriptive analysis techniques. The results of class action research with the application of the ASVI approach show that: the completeness of student activity in the first cycle was 66.2% and experienced an increase in the second cycle of 78.2%. Thus, the activeness of the 2C class students in akidah akhlak lesson after the implementation of the Auditory-Somatic-Visual-Intellectual (ASVI) approach was applied has increased from each cycle of 12%.
The Effect of Professional Training, Job Market Considerations, and Work Environment on Accounting Students' Interest in Careers to be Public Accountants
Authors: Oktaviani Shindy Asri , Diana Apry Linda
Published: July 2023

Interest is one of the considerations for students in the career selection process. A person's interest can be seen from several internal and external factors. This study aimed to determine the effect of professional training, labor market considerations, and work environment on the interest of STEI Jakarta Accounting Students to become Public Accountants. The research method is a descriptive quantitative approach, measured using multiple linear regression-based methods processed with SPSS Version 26.00. The population in this study were undergraduate students majoring in Accounting STEI Jakarta class of 2018 semester eight, who had followed the Auditing 1 and Audit 2 courses. Using the Slovin formula, the number of samples was 75 respondents by determining the sample's criteria. The results showed that professional training had no significant effect on accounting students' interest in having a career as a public accountant. In comparison, the consideration of the labor market and work environment significantly affects the interest of accounting students in a career as a public accountant
Modelling income distributions based on theoretical distributions derived from normal distributions
Authors:   Pomeranian University in Słupsk, Institute of Exact and Technical Sciences, Poland, Sulewski Piotr , Szymkowiak Marcin
Published: July 2023

In income modelling studies, such well-known distributions as the Dagum, the lognormal or the Zenga distributions are often used as approximations of the observed distributions. The objective of the research described in the article is to verify the possibility of using other type of distributions, i.e. asymmetric distributions derived from normal distribution (ND) in the context of income modelling. Data from the 2011 EU-SILC survey on the monthly gross income per capita in Poland were used to assess the most important characteristics of the discussed distributions. The probability distributions were divided into two groups: I – distributions commonly used for income modelling (e.g. the Dagum distribution) and II – distributions derived from ND (e.g. the SU Johnson distribution). In addition to the visual evaluation of the usefulness of the analysed probability distributions, various numerical criteria were applied: information criteria for econometric models (such as the Akaike Information Criterion, Schwarz’s Bayesian Information Criterion and the Hannan-Quinn Information Criterion), measures of agreement, as well as empirical and theoretical characteristics, including a measure based on quantiles, specifically defined by the authors for the purposes of this article. The research found that the SU Johnson distribution (Group II), similarly to the Dagum distribution (Group I), can be successfully used for income modelling.
Impact Of Ambedkar’s Teachings on Community Development As Shown In The God Of Small Things
Authors:   Associate Professor Department of English, Government College for Women, Hisar., Singla Priyanka
Published: July 2023

This paper discusses the influence of Dr. B.R. Ambedkar’s teachings on community development in India, as depicted in Arundhati Roy’s novel The God of Small Things The novel highlights the struggle of the lower-caste population against the rigid social hierarchy prevalent in India, and how Ambedkar’s ideology of social equality and empowerment has impacted the community’s development. Arundhati Roy’s novel The God of Small Things presents a powerful depiction of the impact of Ambedkar’s teachings on community development in India. The novel portrays the lives of twin siblings, Rahel and Estha, who grow up in Ayemenem, a fictional town in Kerala. Their family, the Ipes, is part of the Syrian Christian community, which occupies a higher position in the social hierarchy than the local Dalits. However, the novel also portrays the Dalits’ plight, highlighting the systemic oppression they face, which is deeply entrenched in the social and cultural fabric of the region. This paper analyses the novel’s portrayal of Ambedkar’s ideas and their real-world implications, identifying different ways in which Ambedkar’s teachings have inspired collective action and mobilization, paving the way for more just and equitable social systems.
OROL DЕNGIZI QURIGAN TUBI SHAROITIDA CHЕRKЕZ O‘SIMLIGINI KO‘PAYTIRISH
Authors:   Samarqand davlat universiteti, B Bekchanov
Published: July 2023

Maqolada Orol dengizi
qurigan tubi sharoitida cherkez o‘simligini
ko‘paytirish tajribalarining birinchi yilda olingan
ma’lumotlar keltirilgan. Cherkez –Salsola richteri
Kar. Sho‘radoshlar oilasigi mansub, bo‘yi 1,5-2
metrgacha yetadigan buta. Sertanali; eski
novdalari, po‘stlog‘i kulrang, bir yillik novdalari
oqishroq; tanasi tuksiz. Barglari novdada
navbatma-navbat joylashgan.
Exploring the Influence of Learning Culture on the Effectiveness of Pedagogical Tools within Management Faculties
Authors:   School of Business Management: Sunderland University in London, UK, Habib A , Pius A ,   School of Innovative Leadership and Strategic Management: The Academy for Advance Studies (TAAS), UK
Published: July 2023

The learning culture remained a vital factor and was identified as important due to the changing nature of learning toward flexible and more geographically spread. This research project seeks to explore and better understand the lived experience of the academic staff and undergraduate learner perspectives on the influence of learning culture on the effectiveness of different pedagogical tools within management schools. The study was conducted in four different parts of the world (the United Kingdom, Canada, Germany, and Pakistan), which are unique in their learning cultures and styles. Therefore, it is important to examine the literature to investigate the influence of learning culture on the effective delivery of various pedagogical tools. The research revealed that lectures, PowerPoint presentations (PPTs), lecture notes, class debates, group projects, role play, case studies, internships, guest speakers, mentoring, technology-embedded devices (mobile phone, gaming, simulation, virtual learning environment VLE), multiple choice questions, and reading and writing remained one most effective pedagogical tool but their application is varied throughout four business schools due to the cultural perception of academics and students. The influence of learning culture on the effectiveness of pedagogical tools was found to be challenging. Learning was found to be associated with the values, beliefs, and attitudes that an individual holds and supports.
Non-Approved Uses of Celecoxib and Indomethacin: Pharmacy Students’ Knowledge and Opinions
Authors: Ilesanmi Adekola , Kirkwood Monique , Hailemeskel Bisrat , Fullas Fekadu
Published: July 2023

A survey was conducted among first-year pharmacy students at Howard University College of Pharmacy to measure their level of knowledge and gauge their opinion regarding the off-label uses of two non-steroidal anti-inflammatory drugs (NSAIDs), indomethacin and celecoxib. The average level of knowledge on indomethacin and celecoxib was 36.2% and 31.2%, respectively. Among the five knowledge-based questions on each of these drugs, the highest correct response rate was obtained on indomethacin dosing at 72.9%, and 64.7% on the class of drugs celecoxib belongs to. In the responses to questions on indomethacin, the highest correct response of 72.9% was significantly higher (p<0.05) than responses to other knowledge-based questions, except for the knowledge level on the class of drugs (59.5%; p=0.3257). In the same manner, the correct response rate of 64.7% for the class of drugs that celecoxib belongs to was significantly higher than the response rates for the other questions (p<0.05), except when compared to the response to the question whether hyperplastic polyps and serrated polyps can develop into cancer (41.2%, p=0.0883). The opinions of the students varied, with a majority (55.9%) agreeing that serious diseases should be treated with non-approved medications. In the case of indomethacin, 35.5% of the respondents believed that because of toxicity issues, it should not be used outside the approved indications, while 27.8% believed that the safety has been established and can be used outside the approved use. Most respondents (55.9%) on celecoxib thought colorectal cancer is a serious disease and can be treated with non-approved drugs.
An Unusual Presentation of Autoimmune Thyroid Disease
Authors: Karunathilake PW , Abeyagunawardena S , Ralapanawa U , Jayalath T
Published: July 2023

Introduction: Autoimmune thyroid diseases (AITD) are the most common causes of thyroid gland dysfunctions and non-endemic goiter, which result from dysregulation of the immune system leading to an immune attack on the thyroid. We present a case of an unusual presentation of AITD of a patient presented with pyrexia of unknown origin. Case Presentation: A 40-year previously well female presented to the Professorial Medical Unit Peradeniya with six weeks of bilateral lower limb pain with eight weeks of fever which subsided two weeks before the presentation, associated with lethargy, tiredness, and intermittent episodes of sweating. On examination, her blood pressure was 120/80 mmHg, pulse rate was 80 bpm, and she had tenderness over bilateral thighs and calves. The diagnostic workup revealed low TSH 0.004 µIU/L, T4 20.93 µIU/L, ESR 90 mm/h, CRP 45.1 mmol/L, and anti-thyroid peroxidase antibody (Anti-TPO) level was positive with 32 IU/ml. Therefore, the patient was treated as hyperthyroidism with autoimmune thyroid disease, and she improved with one week of treatment with carbimazole and prednisolone. After two weeks, a free T3 level was done on the review, which revealed a low value indicating Hashitoxicosis as the possible diagnosis. Conclusion: Anti-TPO antibodies can be positive in Hashimoto’s thyroiditis, and Graves’ disease and differentiation can be done using other clinical parameters and preferably by radionuclide studies. Autoimmune thyroid diseases could be presented with unusual manifestations where fever and myalgia would be the only presentation. Therefore, it is essential to have a prompt clinical suspicion and perform serum investigations to exclude any thyroid disease.
Plasmodium Knowlesi Malaria
Authors: Bhattacharyya Sayan
Published: July 2023

Plasmodium knowlesi is a zoonotic Malaria parasite. It is now becoming very important. The vector is anopheles mosquito of different species. Many cases have also been found in offshore island areas of India. It is clinically similar to Falciparum malaria.
Pneumonia before COVID-19 Pandemic Emerging with Accidental Brugada Syndrome and Thrombocytopenia-Serious Association with Good Outcome
Authors: Hassanain Elsayed Yasser Mohammed
Published: July 2023

Rationale: COVID-19 pneumonia emerged in Wuhan city in China on December 31, 2019. However, pneumonia is a serious infection cause. Brugada syndrome [BrS] is a genetic disorder with abnormal electrical activity within the heart. The syndrome carries a higher risk for ventricular fibrillation and sudden death. Thrombocytopenia may be associated with the severe acute respiratory syndrome. Probably Thrombocytopenia is a well-known marker of adverse outcomes in patients diagnosed with pneumonia, as decreased platelet count is linked to severe intravascular coagulation and severe sepsis. Patient concerns: A 50-year-old, bed-ridden smoker Egyptian married male patient was admitted to the intensive care unit with pneumonia and Brugada syndrome [BrS]. Diagnosis: Pneumonia before COVID-19 pandemic emerging with accidental Brugada syndrome and thrombocytopenia. Interventions: Electrocardiography, chest CT scan, oxygenation, and arterial blood gas. Outcomes: Electrocardiographic and clinical stabilization was the only result. Lessons: The presence of mimic COVID-19 pneumonia about 1 year before emerge of the COVID-19 pandemic is interesting and stupendous. The association of Brugada syndrome, renal impairment, and thrombocytopenia in pneumonia are a constellation of serious risk factors.
Covid-19 Spike Protein Physiological Pathogens through Vesicular H+-Adenosine Triphosphatase
Authors: I. Pachankis Yang
Published: July 2023

The mini-review synthesizes the blood-borne Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) human pathogens in its clinical significance through Vesicular H+-Adenosine Triphosphatase (V-ATPase) that lead to pericarditis-induced sudden deaths with acute myocarditis, blood clots, and etc. Early symptoms may arise through rapid acidification in the blood and may guide patient self-awareness and clinical practices. A Phase III clinical trial is reviewed on its phase IV implications, and potentials of experimental medicine in inhibiting V-ATPase protons for Coronavirus Disease 2019 (COVID-19) transmembrane treatment. The mini-review calls for animal tests on Bafilomycin A1 treatment on SARS-CoV-2.
Age-Related Changes in Blood Plasma Alanine aminotransferase in Partridges (Alectoris Chukar) With the Complex Use of Vitamins and an Antistress Drug
Authors: Topchiyeva S.A
Published: July 2023

The article presents the results of the influence of vitamins and an anti-stress drug on the biochemical parameters of partridge blood. In order to identify the dynamics of age-related changes in the activity of alanine aminotransferase in the blood of partridges Alectoris chukar with the complex use of vitamins and an anti-stress drug, we conducted studies on 30 partridges during the period of life from 1, 7, 10, 20, 30, 60 to 90 days. Determination of the activity of the enzyme alanine amino transferase in the blood of partridges was carried out on a Specol 1500 spectrophotometer (Analitik Jena) according to the method of R Rej., M Hoder, U.H Bergmeyer at a wavelength of 540 nm [25]. The object of research was the venous blood of partridges. After the inclusion in the daily diet of partridges of a complex of vitamins (A-20000 IU, D3 - 1250 IU, E - 50 mg) and an anti-stress drug (succinic acid) at a dose of 0.05 g per 1 kg of body weight per day, a tendency to improve biochemical indicators of the activity of the enzyme alanyl aminotransferase. Experimentally revealed a decrease in the activity of the enzyme alanyl aminotransferase in the blood of partridges, which were 1.09, 1.17, 1.13, 1.47, 1.44, 1.37 times greater than the indicators of the latter in the control groups of partridges. The activity value of the alanyl aminotransferase enzyme ranged from 0.02 to 0.06 U/ml, with the maximum value reached at 30 days of age.
Should Downstaging from Neoadjuvant Therapy Impact Selection of Adjuvant Osimertinib? -A Case Report
Authors: DeCarli Kathryn , Mingrino Jennifer , Garcia-Moliner Maria , Koffer Paul , E. Abbas Abbas , G. Azzoli Christopher
Published: July 2023

Existing data do not clearly define the role of Osimertinib in the treatment of resected EGFR-mutated lung cancer. We present the case of a patient with stage IIIA EGFR exon 19 deletion positive NSCLC whose disease was pathologically down staged by neoadjuvant chemoradiation. Future trials should include such patients to inform decisions about adjuvant treatment with respect to survival benefit and toxicity.
Acute Pulmonary Embolism with Multiple Septic Emboli and Pulmonary Infarcts in an IV Drug Abuser with Right-Sided Endocarditis: A Case Report
Authors: Regmi Anup , Prasad Neupane Nirmal , Naura Aishath , Rajlawot Kritisha
Published: July 2023

This case report describes the imaging findings of septic pulmonary embolism (SPE) in a 30-year-old male with a history of intravenous drug abuse for one year. The patient initially presented with high grade fever, shortness of breath, and cough in the emergency department of our institution. The patient was evaluated by chest X-ray, blood cultures, echocardiography, and CT pulmonary angiography which confirmed the diagnosis of SPE, and the causative organism was confirmed to be Staphylococcus aureus. In this case report, we discuss the Chest X-ray findings, and characteristic CT imaging findings of SPE and describe the role of different imaging modalities in the timely diagnosis and management of this highly fatal condition.
A Prospective Cohort Study of Psoriatic Arthritis Prevalence in a Serbian Patients with Psoriasis
Authors: Mahmutovic Elvis , Bisevac Emir , Milidrag Ardea , Bajin Zoran , Boskovic Ksenija , Dolicanin Zana
Published: July 2023

Objective: The aim of this study was to determine the incidence and prevalence of psoriatic arthropathy and to point out the problem of their occurrence in a sample of patients diagnosed with psoriasis. Methods: 109 patients with diagnosed psoriasis and psoriatic arthropathy, took part in the survey. The average age of patients was 48,85±10,11. We analyzed the incidence and prevalence of the psoriatic arthropathy occurrence for the patients with psoriasis. Results: Psoriatic arthropathy registered with patients were those with arthritic changes on: sacroiliac joints with 24 (22,02%) patients, 19 (79,17%) male and 5 (20,83%) female (p<0,001); spine with 11 (10,09%) patients, 6 (54,56%) male and 5 (45,45%) female (p=0,578); peripheral joints with 74 (67,89%) patients, 33 (44,59%) male and 41 (55,41%) female (p<0,01). When comparing the symptoms, most of the patients (63,30%) skin changes were represented before arthritis, for 27,52% patients arthritis preceded the skin changes, and for 9,17% patients the changes were simultaneous, Conclusion: Psoriatic arthropathy occurs more often in median age (31 to 50 years old) and it is more common for men than women. For most patient’s psoriatic skin changes preceded joints affection, with the most common ones being polyarthritis.
Study of Normal and Pathogenic Bacteria in Medicinal Probiotics
Authors: Das Trisha , Bhattacharyya Sayan , Datta Shibani
Published: July 2023

There are many medicinal probiotics available which are usually bacteria but sometimes also yeasts. These medicinal probiotics, sometimes contain some undesired products like pathogenic aerobic or anaerobic bacteria. These are hitherto unexplored areas of public health research. Hence here we have tried to study the presence of these types of pathogenic bacteria. Some pathogens were found in the medicinal probiotics.
True Isolated Deep Femoral Artery Aneurysm Treated with Endovascular Technique: Case Report and Literature Review
Authors: Athayde Soares Rafael de , Martins Cury Marcus Vinicius , Yoshimi Futigami Aline
Published: July 2023

In this paper, we aimed to report an alternative endovascular treatment in a patient with an isolated deep femoral artery aneurysm. A 49-year-old male patient, with no comorbidities, was admitted with right limb pain, mainly in the thigh, associated with a weakness and difficulty walking. The patient was submitted to a duplex ultrasound, that suggested a deep femoral artery aneurysm, with 6 cm diameter, confirmed with CT angiogram. The patient was scheduled to undergo endovascular treatment of the deep femoral artery aneurysm with a covered self-expandable 9x100 Solaris and embolization of the first branch of the Deep femoral artery with Azur coils 2 4x5, 6x10, 6x15 and 6x20. The patient was discharged from the hospital two days after the surgery with no complications, palpable pedal pulses on Aspirin 100mg and Clopidogrel 75mg. At year follow-up the patient was asymptomatic and duplex showed patent stent without evidence of endoleak.
Los retos asumidos por la educación superior tras la pandemia del COVID-19 en Colombia: el nuevo paradigma académico
Authors: Palencia Buelvas Ronald Yesid , Díaz Herrera Yeimys Judith , Pérez Domínguez Wilder Smith , Bustamante Elles Geraldine Esther , Guerra Martínez Dagoberto José
Published: July 2023

La presente investigación tuvo como objetivo la identificación de los retos que las IES de Colombia deben asumir tras la pandemia del COVID-19. Para ello se seleccionaron siete documentos hemerográficos principales que han indagado sobre el tema a través de investigaciones de campo. Se realizó un análisis de los documentos y su respectiva codificación en Atlas.Ti que permitió la obtención de variables principales como retos logísticos, retos curriculares, retos financieros y retos sociales para la redacción de los resultados obtenidos; además se consultaron otras fuentes de información que permitió la triangulación de los contenidos a través del uso de bases de datos de libre acceso como Scielo, Zotero y diferentes repositorios universitarios como el de la Universidad Nacional de Colombia, Universidad Nacional Autónoma de México y Universidad del Norte.
Research on the Teaching Method of Beauty and Skin Care Technology Course Based on Action Orientation
Authors:   Yixin Publisher, Zhang Lin , Wang Juan
Published: July 2023

The action-oriented teaching method based on the principle of action-oriented teaching process is helpful to the cultivation of students’ comprehensive professional ability. The course of “beauty and skin care technology” is a professional core course for the major of medical beauty technology. It is closely related to the examination of beautician qualification certificate and belongs to the course of integration of courses and certificates. The course is mainly based on human aesthetics, common sense of physiological anatomy, theory of traditional Chinese medicine and massage techniques to study skin care technology, so as to delay aging and improve skin beauty problems. It is required that the trained talents can become first-class beauticians, beauty tutors and beauty consultants in the beauty industry. Under the traditional teaching mode of this major, the teaching method is single, the teacher is dominant and the teaching content is divorced from practice. Combined with the work process, the teaching method should be improved and innovated by using the guiding text teaching, project teaching, role-playing teaching, situational simulation teaching and case study. These action-oriented teaching methods can effectively promote the training of senior medical beauty technology professionals with scientific thinking and strong comprehensive professional ability.
Research on the Application of Comics Elements in the Teaching of Chinese as a Foreign Language
Authors:   Yixin Publisher, Du Haifeng
Published: July 2023

This paper aims to study the application of comic elements in teaching Chinese as a foreign language and explore their role in enhancing learning outcomes and classroom engagement. Comics, through their visual representation of language and culture, help learners better understand and memorize Chinese knowledge. The images stimulate learners’ imagination and help them establish connections between vocabulary, grammar, and sentence patterns. With interesting storylines, humorous dialogues, and exaggerated expressions, comics encourage learners to actively participate in classroom activities. Through comics, learners can gain an understanding and appreciation of the unique aspects of Chinese culture, and foster their interest and comprehension of traditional and contemporary Chinese culture. Elements such as character images, social customs, and cultural backgrounds depicted in comics facilitate learners’ understanding and integration into Chinese society. The structure of this paper begins with an introduction highlighting the importance of teaching Chinese as a foreign language and the potential of comic elements. Subsequently, an analysis of survey results reveals learners’ attitudes and opinions toward comic-based teaching. Based on the feasibility study, specific design proposals for incorporating comic elements into Chinese language classrooms are presented. The conclusion and discussion section summarizes the research findings and explores limitations and future directions for the use of comic elements in teaching Chinese as a foreign language. Through this study, we conclude that the introduction of comic elements in Chinese language instruction enhances learners’ interest and engagement while promoting their overall language and cultural competencies. Finally, the paper concludes with a final section emphasizing the significance of integrating comic elements into teaching Chinese as a foreign language and outlining future research directions and challenges.
Estudio descriptivo de delitos cometidos por menores de edad en los últimos años en Chile
Authors: Rojas Sepulveda Natalia
Published: July 2023

El presente artículo tiene como objetivo presentar los resultados obtenidos, tras realizar un análisis descriptivo acerca de detenciones de menores de edad entre los años 2019 y 2021 en Chile. Dentro de este estudio se analizaron 73.239 registros de detenciones que involucran a este rango etario, con el objeto de entender el contexto y características de este tipo de detenidos en los últimos 3 años. Para esto se han considerado variables como edad, sexo, delitos cometidos y comunas donde son detenidos los menores de 18 años. Al poner esta información en contexto podremos evaluar si efectivamente hay un aumento de la participación de menores en hechos delictuales, y si esto coincide con la percepción de la población y con lo que se transmite en los medios de comunicación, de que hay una mayor participación de adolescentes en diversos delitos, especialmente delitos violentos. Se trata de una investigación en base a datos secundarios, donde se emplea una estrategia cuantitativa con un diseño no experimental, a fin de desarrollar una indagación exploratoria.
Historia de la educación policial en Colombia
Authors: Barrera Juan Aparicio
Published: July 2023

Se realizó un estudio cuyo objetivo fue realizar una descripción histórica de la educación policial para la policía en Colombia, para lo cual como método se realizó una revisión de textos históricos sobre la Policía Nacional y normatividad colombiana sobre la educación policial en el siglo xx y xxi. Como resultado, se pudo apreciar que pasó de una concepción de un oficio enteramente pragmático que no requería ningún tipo de estudio formal a la idea paulatina de la profesión policial en donde los policías tenían que pasar por una escuela de formación y posteriormente capacitarse y especializarse para asumir sus labores diarias en las distintas direcciones del servicio. El nivel formativo de los policías y el paso a la educación formal estuvo de la mano de la evolución histórica de la educación en Colombia y de exigencias en respeto de los Derechos Humanos. En conclusión, se ha recorrido un largo proceso en donde los policías nacionales han pasado del pragmatismo en temas educativos a la profesionalización en cuanto a procesos de educación formal, formación continua, entrenamiento y reentrenamiento para el servicio.
« D’ailleurs, bien des femmes ont écrit avant moi1 » : le cas de Laure Conan, à la fois pionnière et héritière
Authors: Fournier Virginie
Published: July 2023

L’autrice examine l’héritage littéraire convoqué dans le roman Angéline de Montbrun à travers le prisme des études sur l’œuvre de Charlotte Brontë. Cette perspective lui permet de reconsidérer l’étiquette de pionnière attribuée à Laure Conan en raffinant encore le système de référence et en isolant des éléments véritablement structurants de cet héritage pour ainsi relever des enjeux particuliers à la pratique de l’écriture des femmes. La critique conanienne s’est beaucoup intéressée à l’intertextualité d’Angéline de Montbrun, mais l’héritage anglais n’a pas encore été examiné en détail. L’utilisation des études brontiennes permet, entre autres, de relever le potentiel métadiscursif de certains éléments du récit à l’égard des conditions d’écriture des femmes, notamment par des structures et des stratégies narratives issues du gothique de Barbe bleue (Bluebeard Gothic). Ce concept montre comment, dans des œuvres écrites par des femmes au xixe siècle, des éléments gothiques sont couplés à des références au conte de Charles Perrault et permet d’ouvrir la question du legs dans l’œuvre de Laure Conan.
Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase
Authors: Koudelková Lenka , Pelantová Markéta , Brůhová Zuzana , Sztacho Martin , Pavlík Vojtěch , Pánek Dalibor , Gemperle Jakub , Talacko Pavel , Brábek Jan , Rösel Daniel
Published: July 2023

The activation of Src kinase in cells is strictly controlled by intramolecular inhibitory interactions mediated by SH3 and SH2 domains. They impose structural constraints on the kinase domain holding it in a catalytically non-permissive state. The transition between inactive and active conformation is known to be largely regulated by the phosphorylation state of key tyrosines 416 and 527. Here, we identified that phosphorylation of tyrosine 90 reduces binding affinity of the SH3 domain to its interacting partners, opens the Src structure, and renders Src catalytically active. This is accompanied by an increased affinity to the plasma membrane, decreased membrane motility, and slower diffusion from focal adhesions. Phosphorylation of tyrosine 90 controlling SH3-medited intramolecular inhibitory interaction, analogical to tyrosine 527 regulating SH2-C-terminus bond, enables SH3 and SH2 domains to serve as cooperative but independent regulatory elements. This mechanism allows Src to adopt several distinct conformations of varying catalytic activities and interacting properties, enabling it to operate not as a simple switch but as a tunable regulator functioning as a signalling hub in a variety of cellular processes.
Comparing mouse and human brains
Authors: Wong Hovy Ho-Wai , Chou Christina You Chien , Watt Alanna Jean , Sjöström Per Jesper
Published: July 2023

Inhibitory circuit motifs in the mouse brain and the human brain are strikingly similar.
Student Opinions on Teaching Voice Training Lessons with Distance Education
Authors: Sultan ÜNVER Ruveyda , TEMİZ Ebru
Published: July 2023

Covid-19 pandemisi tüm dünyayı etkisi altına almış ve gerek günlük yaşamı gerekse eğitim faaliyetlerini önemli ölçüde etkilemiştir. Zor koşullar altında ilerleyen bu süreçte eğitim öğretim faaliyetlerinin aksamaması amacıyla eğitimin
uzaktan eğitim ile sürdürülmesi kararı alınmıştır. Bu sistem, her ne kadar pandemi koşulları içinde gerekli ve teorik derslerin işlenebilmesi için elverişli olsa da ses eğitimi gibi performansa dayalı bir dersin etkili bir şekilde
işlenebilmesi konusunda tartışmaya açık bir durum sergilemektedir. Bu doğrultuda araştırmada, müzik öğretmenliği lisans programında öğrenim gören öğrencilerin ses eğitimi dersinin uzaktan eğitimle işlenmesine ilişkin görüşlerini
tespit etmek ve bu yolla uzaktan eğitimle işlenen ses eğitimi dersinin gerçekleştirilebilirliği ve verimliliği hakkında bilgi sahibi olmak amaçlanmıştır. Araştırma için Ankara Müzik ve Güzel Sanatlar Üniversitesi Etik Kurulunun
07.01.2022 tarih ve 2022/2 sayılı kararına göre etik kurul izni alınmıştır. Araştırmada nicel araştırma yöntemlerinden tarama modeli kullanılmış ve 10 farklı üniversiteden toplam 105 öğrencinin görüşleri alınmıştır. Veriler dijital
ortamda anket aracılığıyla toplanmış ve betimsel analiz tekniği ile analiz edilmiştir. Araştırma sonucunda; öğrencilerin derse büyük oranda evden katıldıkları, derse katılmak için çoğunlukla telefon kullanmayı tercih ettikleri,
derste büyük oranda teknik aksaklıklarla karşılaştıkları, ders için ihtiyaç duydukları kaynaklara çoğunlukla internet üzerinden ve dersi yürüten akademisyenle iletişime geçerek ulaştıkları, derse yardımcı kaynak olarak çoğunlukla
YouTube videolarından faydalandıkları, anket genelinde olumlu görüş bildirmelerine rağmen son iki anket maddesine verdikleri yanıtlar ile uzaktan eğitimle işlenen ses eğitimi dersine karşı motivasyon düzeylerinin düşük olduğu ve
mevcut koşullar içinde dersi yararlı bulmalarına karşın dersin genel verimliliğini düşük buldukları sonuçlarına ulaşılmıştır.