bluuebunny/crossref_metadata_2025 huggingface dataset:
Diversity of fungi from marine inundated wood from the Bay of Fundy, Nova Scotia, Canada
Authors: Adams Sarah J. , Walker Allison K.
Published: July 2023

Marine fungi play an integral role in the decomposition of intertidal organic substrata but remain understudied in cold-water habitats including Atlantic Canada. Marine inundated wood from the intertidal zone was sampled from 30 sites along the Bay of Fundy coastline in Nova Scotia, Canada. Wood types studied included attached and loose intertidal wood, and driftwood. Emergent fungi were cultured and identified using ITS (internal transcribed spacers) rDNA barcoding. Two hundred and twenty cultures representing 86 fungi are reported. Sixty-one fungi were new records for the Bay of Fundy, 41 are first records from the marine environment, and 19 fungi are potentially new to science. Fungi identified included eight obligate marine fungi, with the remaining fungi being facultatively marine. Eight ascomycetes were soft rot fungi; this ecological strategy for decaying woody material in cold-water marine environments is discussed. Historical records and roles of wood type and site on fungal colonization are discussed.
Clinical relevance of clonal hematopoiesis and its interference in cell-free DNA profiling of patients with gastric cancer
Authors: Lee Kwang Seob , Lee Choong-Kun , Kwon Soon Sung , Kwon Woo Sun , Park Sejung , Lee Seung-Tae , Choi Jong Rak , Rha Sun Young , Shin Saeam
Published: July 2023

Objectives

Clonal hematopoiesis (CH) is a condition in which healthy individuals have somatic mutations in hematopoietic stem cells. It has been reported with increased risk of hematologic malignancy and cardiovascular disease in the general population, but studies of Korean populations with comorbid disease entities are scarce.

Methods

White blood cells (WBCs) from patients with gastric cancer (GC) (n=121) were analyzed using a DNA-based targeted (531 genes) panel with customized pipeline designed to detect single nucleotide variants and small indels with low-allele-frequency of ≥0.2 %. We defined significant CH variants as having variant allele frequency (VAF) ≥2 % among variants found in WBCs. Matched cell-free DNA (cfDNA) samples were also analyzed with the same pipeline to investigate the false-positive results caused by WBC variants in cfDNA profiling.

Results

Significant CH variants were detected in 29.8 % of patients and were associated with age and male sex. The number of CH variants was associated with a history of anti-cancer therapy and age. DNMT3A and TET2 were recurrently mutated. Overall survival rate of treatment-naïve patients with stage IV GC was higher in those with CH, but Cox regression showed no significant association after adjustment for age, sex, anti-cancer therapy, and smoking history. In addition, we analyzed the potential interference of WBC variants in plasma cell-free DNA testing, which has attracted interest as a complementary method for tissue biopsy. Results showed that 37.0 % (47/127) of plasma specimens harbored at least one WBC variant. VAFs of interfering WBC variants in the plasma and WBC were correlated, and WBC variants with VAF ≥4 % in WBC were frequently detected in plasma with the same VAF.

Conclusions

This study revealed the clinical impact of CH in Korean patients and suggests the potential for its interference in cfDNA tests.
Platform regulation and “overblocking” – The NetzDG discourse in Germany
Authors: Pohlmann Jens , Barbaresi Adrien , Leinen Peter
Published: July 2023

This paper analyzes the internet policy discourse regarding the German Network Enforcement Act (NetzDG) in different media settings. We examine the conversation about this highly controversial anti-hate speech law on IT blogs, websites, and in daily German newspapers. We compare the positions brought forward in these different media environments concerning one of the most important topics within the discussion about the NetzDG, specifically the question of whether or not the law will result in censorship, limiting users’ freedom of expression. We employ pretrained transformer-based language models to detect and quantify recurring arguments in the debate.
Removal behavior of Zn and alkalis from blast furnace dust in pre-reduction sinter process
Authors: Zhao Guiqing , Li Ruoyan , Xing Xiangdong , Ju Jiantao , Li Xinyi , Zu Jian
Published: July 2023

In this study, iron concentrate and blast furnace dust were used as raw materials, and graphite was used as a reducing agent for mixing and briquetting. The briquettes were roasted in a high-temperature tube furnace at different temperatures and held for a certain time to simulate the pre-reduction sintering process. The effects of dust content, reduction time, and reduction temperature on the removal rate of zinc, potassium, and sodium and the metallization rate of the pre-reduction sintered products were investigated. The reduced briquettes were characterized by X-ray diffraction, scanning electron microscopy-energy dispersive spectroscopy, and flame atomic absorption spectroscopy to further explore the mechanisms of zinc, potassium, and sodium removal. The Zn removal rate and metallization rate increased gradually with the increase in dust content, reaching 97.57% and 87.14% at 30% dust content, respectively. Both K and Na removal rates reached a maximum of 83.57% and 94.78%, respectively, at 25% dust content. With the increase in reduction time and temperature, the removal rate of the three elements and the metallization rate gradually increased. When the briquettes with 20% blast furnace (BF) dust content were reduced at 1,200℃ for 20 min, the removal rates of zinc, potassium, and sodium reached 95.66%, 79.97%, and 91.49%, respectively, and the metallization rate reached 84.77%. It shows that the pre-reduction sintering process can effectively remove Zn, K, and Na from the BF dust and meet the requirements of subsequent BF production. The research results can provide some theoretical basis for industrial production.
The DEAD-box RNA helicase Dbp5 is a key protein that couples multiple steps in gene expression
Authors: Querl Luisa , Krebber Heike
Published: July 2023

Cell viability largely depends on the surveillance of mRNA export and translation. Upon pre-mRNA processing and nuclear quality control, mature mRNAs are exported into the cytoplasm via Mex67-Mtr2 attachment. At the cytoplasmic site of the nuclear pore complex, the export receptor is displaced by the action of the DEAD-box RNA helicase Dbp5. Subsequent quality control of the open reading frame requires translation. Our studies suggest an involvement of Dbp5 in cytoplasmic no-go-and non-stop decay. Most importantly, we have also identified a key function for Dbp5 in translation termination, which identifies this helicase as a master regulator of mRNA expression.
Multi-sensor remote sensing image alignment based on fast algorithms
Authors: Shu Tao
Published: July 2023

Remote sensing image technology to the ground has important guiding significance in disaster assessment and emergency rescue deployment. In order to realize the fast automatic registration of multi-sensor remote sensing images, the remote sensing image block registration idea is introduced, and the image reconstruction is processed by using the conjugate gradient descent (CGD) method. The scale-invariant feature transformation (SIFT) algorithm is improved and optimized by combining the function-fitting method. By this way, it can improve the registration accuracy and efficiency of multi-sensor remote sensing images. The results show that the average peak signal-to-noise ratio of the image processed by the CGD method is 25.428. The average root mean square value is 17.442. The average image processing time is 6.093 s. These indicators are better than the passive filter algorithm and the gradient descent method. The average accuracy of image registration of the improved SIFT registration method is 96.37%, and the average image registration time is 2.14 s. These indicators are significantly better than the traditional SIFT algorithm and speeded-up robust features algorithm. It is proved that the improved SIFT registration method can effectively improve the accuracy and operation efficiency of multi-sensor remote sensing image registration methods. The improved SIFT registration method effectively solves the problems of low accuracy and long time consumption of traditional multi-sensor remote sensing image fast registration methods. While maintaining high registration accuracy, it improves the image registration speed and provides technical support for a rapid disaster assessment after major disasters such as earthquakes and floods. And it has an important value for the development of the efficient post-disaster rescue deployment.
Rickets in proximal renal tubular acidosis: a case series of six distinct etiologies
Authors: Singhania Pankaj , Dhar Abhranil , Deshpande Aditya , Das Debaditya , Agrawal Neeti , Chakraborty Partha Pratim , Bhattacharjee Rana , Roy Ajitesh
Published: July 2023

Objectives

Proximal renal tubular acidosis (pRTA) is characterized by a defect in the ability of the proximal convoluted tubule to reabsorb bicarbonate. The biochemical hallmark of pRTA is hyperchloremic metabolic acidosis with a normal anion gap, accompanied by appropriate acidification of the urine (simultaneous urine pH <5.3). Isolated defects in bicarbonate transport are rare, and pRTA is more often associated with Fanconi syndrome (FS), which is characterized by urinary loss of phosphate, uric acid, glucose, amino acids, low-molecular-weight proteins, and bicarbonate. Children with pRTA may present with rickets, but pRTA is often overlooked as an underlying cause of this condition.

Case presentation

We report six children with rickets and short stature due to pRTA. One case was idiopathic, while the remaining five had a specific underlying condition: Fanconi-Bickel syndrome, Dent's disease, nephropathic cystinosis, type 1 tyrosinemia, and sodium-bicarbonate cotransporter 1-A (NBC1-A) defect.

Conclusions

Five of these six children had features of FS, while the one with NBC1-A defect had isolated pRTA.
Framework for identifying network attacks through packet inspection using machine learning
Authors: Shanker Ravi , Agrawal Prateek , Singh Aman , Bhatt Mohammed Wasim
Published: July 2023

In every network, traffic anomaly detection system is an essential field of study. In the communication system, there are various protocols and intrusions. It is still a testing area to find high precision to boost the correct distribution ratio. Many authors have worked on various algorithms such as simple classification, K-Means, Genetic Algorithm, and Support Vector Machine approaches, and they presented the efficiency and accuracy of these algorithms. In this article, we have proposed a feature extraction technique known as “k-means clustering,” which has its roots in signal processing and is employed to divide a set of n observations into k clusters, each of which has its origin from the observation with the closest mean. K-Means method is applied in this study to investigate the stream and its implementation and applications using Python and the dataset on the KDDcup99. The effectiveness of the outcome indicates the planned work’s efficiency in relation to other widely available alternatives. Apart from the applied method, a web-based framework is designed, which can inspect an actual network traffic packet for identifying network attacks. Instead of using a static file for testing the network attack, a web page-based solution uses database to collect and test the information. Real-time packet inspection is provided in the proposed work for identifying new attacks.
Forkhead Box P4 promotes the proliferation of cells in colorectal adenocarcinoma
Authors: Liu Aidong , Pang Jiuling , Xiong Guangyi , Liu Qi , Chen Liming
Published: July 2023

Objectives

Forkhead Box P4 (FOXP4) is a transcription factor that promotes tumor formation and progression. However, studies on its roles in colorectal adenocarcinoma (CRAC) and cell proliferation regulation are few to date. This work investigates the expression of FOXP4 in CRAC, explores the characteristic of FOXP4 in different clinicopathological features, and analyzes its regulation of cell proliferation.

Methods

The GEPIA database was used to predict the trend of FOXP4 expression in colon cancer and normal mucosa. Tumor tissue and normal paracancerous mucosal tissue were sampled from 64 cases diagnosed with CRAC and who were receiving radical surgery at Tianjin Hospital from January 2017 and December 2022. FOXP4 and proliferating cell nuclear antigen (PCNA) were detected by the immunohistochemistry EnVision method. The colon cancer cell lines SW480, HCT15, and SW620 and the normal colon cell line NCM460 were selected, and expression of FOXP4 was detected by the Western blot method. The siRNA-FOXP4 plasmid was synthesized and transfected with SW480 and HCT15 cell lines, respectively, to establish si-FOXP4 groups, and empty vector transfection group (NC-FOXP4) and blank control group (NC) was set up. The expression levels of FOXP4 and PCNA were detected by the Western blot method, while the cell proliferation activity was assessed using CCK-8. Normally distributed quantitative data were compared between two and more groups with ANOVA (SNK-based pairwise comparison), while intergroup enumeration data comparisons were performed through χ
2 test and assessed through linear correlation analysis.

Results

GEPIA-based prediction shows a potential rise in FOXP4 expression in colon cancer. The rate of positive FOXP4 expression is significantly higher in CRAC tissue than in normal mucosa (p<0.05). The difference in FOXP4 is statistically significant in the comparison of maximum tumor diameter and depth of invasion in CRAC (p<0.05) but not in the comparison of gender, age, degree of differentiation, tumor focus, tumor embolism, and lymph node metastasis (p>0.05). The expression levels of FOXP4 and PCNA in CRAC are positively correlated (p<0.05). FOXP4 expression is significantly higher in cell lines SW480, HCT15, and SW620 than in cell line NCM460. The cell proliferation activity and PCNA expression are significantly lower in si-FOXP4 group than in NC-FOXP4 and NC groups for cell lines SW480 and HCT15.

Conclusions

FOXP4 is highly expressed and has a proliferative effect on tumor cells in CRAC.
Freedom and Heteronomy in the Anthropocene
Authors: Stoner Alexander M. , Dahms Harry F.
Published: July 2023

The concept of the Anthropocene reflects a particular meaning of the “human” as it exists in society, and a specific understanding of freedom, which only became possible at the close of the twentieth century. Whereas Enlightenment thinkers such as Kant, Rousseau, and Adam Smith attempted to grasp the potential for humanity to be changed through society in a self-conscious process of attaining freedom, the “Age of Man” today appears entirely disconnected from human agency. Indeed, the Anthropocene is associated not with the flourishing of life but with the sixth mass extinction. Drawing insight from classical and contemporary critical theory, this paper seeks to explicate the emancipatory potential within the concept of the Anthropocene, and the ways in which this potential is blocked by material circumstances that masquerade as “freedom.”
Liberté et communauté en Islam
Authors: Triki Fathi
Published: July 2023

L’individu peine à émerger dans les sociétés musulmanes qui vivent toujours sous l’impérium de la communauté. La dignité du vivre-ensemble ne devient réelle que dans la mesure où l’individu se libère et choisit son mode de vie. La dignité implique la liberté et la liberté conduit à la dignité. La question est de savoir si l’islam est un obstacle à cette libération de l’individu et s’il englobe en son sein le communautarisme. Est-il vrai que l’Islam est une religion de l’identité, de la communauté et donc de l’exclusion de la dignité individuelle ?
Sport und Freiheit
Authors: Gebauer Gunter
Published: July 2023

In den letzten Jahren hat sich der internationale Sport so grundlegend gewandelt, dass er in Gefahr ist, seine historisch gewachsene Identität aufzugeben. Nicht seine bildliche Qualität, seine Intensität und Spannung haben sich verändert; sie haben im Gegenteil noch zugenommen. Auf einem anderen Feld haben sich Dinge ereignet, die dem Sport einen neuen Charakter geben. Doch diese Veränderungen gehören zu einem Ausschnitt der Wirklichkeit, der auf den Fernsehbildern und in den Kommentaren nicht erkennbar ist; für die meisten Zuschauer bleibt er unsichtbar.
Soft Paternalism and Freedom in the Age of Artificial Intelligence – Through the “tactfulness (融通無碍 Yuzu-Muge)” of 華厳学 Hua-Yan philosophy
Authors: Suzuki Shoko
Published: July 2023

Living in an era of technological innovations, we must understand and trust them to benefit from these new technologies. In this context, paternalism is renewed as the so-called “soft-” or “Libertarian paternalism”. How can we face it and ensure freedom in the vortex of wellmeaning advice and persuasion? This paper will discuss 1. the characteristics of freedom since the 18th century from the perspective of the Enlightenment discourse in Germany by Mendelssohn and Kant, 2. the conditions for freedom in the contemporary age of accelerating technological innovation, and 3. from trans-modernism, rethinking the dichotomy between otherness and autonomy, coercion and freedom, by the idea of 融通無碍 Yuzu-Muge, tactfulness in 華厳学 Hua-Yan Philosophy.
Research Hotspots and Trends in Home-Based Cardiac Rehabilitation: A Bibliometric Visualization Analysis
Authors: Jianchao Li , Yu Zhao , Chunjing Tao , Sisi Zhang , Rongjing Ding
Published: July 2023

Objective: This research was aimed at determining research hotspots and major topics in the field of international home-based cardiac rehabilitation (HBCR) over the past 20 years, and exploring future trends in HBCR.

Methods: A total of 757 research articles from 2002 to 2022, with themes of home-based cardiac rehabilitation, were included in the core collection database of Web of Science. CiteSpace software was used for literature metrology and visualization analysis.

Results: (1) The total number of research articles on HBCR is increasing. (2) Research hotspots in HBCR include the effectiveness of rehabilitation after coronary heart disease or heart failure; quality of life; mental health; and home rehabilitation after COVID-19. (3) Research trends in HBCR include wearable intelligent technology; telerehabilitation; lifestyle interventions; and home-based rehabilitation prescriptions for exercise, nutrition, psychology and continuous management.

Conclusion: The effects of HBCR have been continuously verified. Research has focused primarily on secondary prevention and rehabilitation after coronary heart disease and heart failure. More attention must be paid to improving patients’ quality of life by HBCR. Telerehabilitation based on wearable intelligent technology, home-based lifestyle interventions and continuous management are future trends of HBCR development.
And Then Suddenly, It Was Simply Everywhere
Authors: Acierto Alejandro T.
Published: July 2023

This article offers an artistic reflection on the Queer Percussion Research Group Zine Collection (2023) through the concept of shimmering as a queer political and positional affect across light and sound. With over a dozen contributions that consist of artist publications, pamphlets, and experimental scores, the Zine Collection was produced by folks “interested in the intersection of queerness and percussion in a variety of contexts.” While glitter scatters across contributions from inside the clear plastic folio, this writing recounts the impact and implications of glitter’s trace as it moves between surfaces, bodies, and skins. Rather than declaring glitter as inherently queer, this work considers the ways that glitter—and other glistening things—“blur the body,” as Michele White writes, and disrupts normative presentations of gender. Its reflective surfaces thus become entangled with the slippages between the masculine/feminine binary, shifting the legibility of the (gendered) surface that might allow viewers to see otherwise. Thinking with and alongside glitter’s shimmering properties allows for a reconceptualization of queer, which might enable further forms of conceptual movement and framing that extend its theoretical capacity.
LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma
Authors: Alborzinia Hamed , Chen Zhiyi , Yildiz Umut , Freitas Florencio Porto , Vogel Felix C E , Varga Julianna Patricia , Batani Jasmin , Bartenhagen Christoph , Schmitz Werner , Büchel Gabriele , Michalke Bernhard , Zheng Jashuo , Meierjohann Svenja , Girardi Enrico , Espinet Elisa , Flórez Andrés F , dos Santos Ancely Ferreira , Aroua Nesrine , Cheytan Tasneem , Haenlin Julie , Schlicker Lisa , Xavier da Silva Thamara N , Przybylla Adriana , Zeisberger Petra , Superti‐Furga Giulio , Eilers Martin , Conrad Marcus , Fabiano Marietta , Schweizer Ulrich , Fischer Matthias , Schulze Almut , Trumpp Andreas , Friedmann Angeli José Pedro
Published: July 2023

Ferroptosis has emerged as an attractive strategy in cancer therapy. Understanding the operational networks regulating ferroptosis may unravel vulnerabilities that could be harnessed for therapeutic benefit. Using CRISPR‐activation screens in ferroptosis hypersensitive cells, we identify the selenoprotein P (SELENOP) receptor, LRP8, as a key determinant protecting MYCN‐amplified neuroblastoma cells from ferroptosis. Genetic deletion of LRP8 leads to ferroptosis as a result of an insufficient supply of selenocysteine, which is required for the translation of the antiferroptotic selenoprotein GPX4. This dependency is caused by low expression of alternative selenium uptake pathways such as system Xc−. The identification of LRP8 as a specific vulnerability of MYCN‐amplified neuroblastoma cells was confirmed in constitutive and inducible LRP8 knockout orthotopic xenografts. These findings disclose a yet‐unaccounted mechanism of selective ferroptosis induction that might be explored as a therapeutic strategy for high‐risk neuroblastoma and potentially other MYCN‐amplified entities.
Fibers in Asphalt Mixture: A State-of-The-Art Review
Authors: Masri Ts. Dr. Khairil Azman , A.O.A. Baqadeem
Published: July 2023

The use of fiber in asphalt mixture is gaining popularity as it can improve the mechanical properties of the asphalt pavement and enhance its durability and longevity. The main objective of this review is to discuss the recent research on the use of fiber in asphalt mixture and to provide an overview of its effects on the mechanical properties of asphalt. The article presents a review of the literature on the use of different types of fibers in asphalt mixture, including natural fibers, synthetic fibers, and glass fibers. The mechanical properties evaluated include stiffness, fatigue resistance, crack resistance, and rutting resistance. The review highlights the potential benefits of using fiber in asphalt mixture, including improved stiffness and crack resistance, reduced rutting, and increased fatigue resistance. However, the effectiveness of fiber in improving the mechanical properties of asphalt is influenced by various factors, such as fiber type, content, and distribution.
Review of Research on Coarse Aggregate Reinforcement of Recycled Concrete
Authors: Li Zhang , M.N.A. Azman  , R.P Jaya
Published: July 2023

In order to explore the effective method of strengthening recycled concrete coarse aggregate，improve the effective utilization rate of recycled concrete, respond to the development requirements of green buildings and green building materials. By reading a large number of existing research methods and documents, the advantages and disadvantages of various strengthening methods for recycled concrete coarse aggregate in recent years are analyzed and summarized. The main strengthening methods of reclaimed coarse aggregate are physical strengthening, chemical strengthening and gradation strengthening through comparative analysis, more effective strengthening methods are not single, but a combination of two or more methods. Effectively combine gradation strengthening and chemical strengthening, can better improve the mechanical properties of recycled concrete coarse aggregate and durability. There is little research on the failure mechanism of transition zone and strengthening the interface transition zone of recycled concrete, and there are few literatures about harmless treatment of chemically strengthened slurry. These two aspects can be explored and analyzed in the future research.
The Analysis of 21st Century Learning Implementation and Competency Achievement of Junior High School Students in 3T Regions
Authors: Gunadi Gunadi , Haryono Haryono , Purwanti Eko
Published: July 2023

Providing students with competency is one of the challenge of 21st Century learning. The competencies include critical thinking and problem solving skills, communication and collaboration, creativity and innovation, as well as information literacy and technology media. This study aims to analyze the implementation of 21st century learning and the achievement of competencies of junior high school students who are in the frontier, outermost, and least developed areas of Melawi Regency, West Kalimantan Province. The method of this study was descriptive-analytic qualitative with the type of the research was case study. The results shows that the implementation of 21st century learning at Junior High School in the 3T area shows a moderate or medium category. The scores for each indicator are: planning (70.4%), learning implementation (73.4%), and assessment and evaluation (70.8%). The achievement of the 21st century competence of students gets medium category. The scores for each indicator are: critical thinking and problem solving skills (54%), communication skills (73%), collaboration skills (70%), creativity and innovation (48%), and information and media literacy (60%). The implication of this research is for the prospective teachers or new teachers who work in the 3T area. So that, they would know the conditions and prepare various strategies and learning approaches to apply based on the local conditions in improving studentsâ€™ competency.
The Development of an Android-Based Educational Game “Orang Kayo Hitam” Jambi Folklore to Improve Student Motivation at Al-Falah Kindergarten Jambi
Authors: Khaira Ulfa , Indryani Indryani , Rosyadi Akhmad Fikri
Published: July 2023

Fairy tales based on folklore are the right media to raise awareness of moral values. However, practically, it is often found that students are not interested in this kind of learning activity. The lack of interest in participating the learning activities can be caused by the learning media used by the teacher that is not attractive enough. This study developed and tested the feasibility and the effectiveness of an Android-based Orang Kayo Hitam Jambi folklore educational game. This study used the research and development method with the 4D model consisting of defining, designing, developing, and disseminating. The result of this study shows that the product feasibility assessment score through product validation from media experts was 3.8 (very feasible) and from material experts was 3.85 (very feasible). The effectiveness of this android-based Orang Kayo Hitam Jambi folklore educational game was tested through the hypothesis. The type of experimental research method used is One-Group Pretest-Postest Design in which the experiment is carried out in one group without a comparison group. The sample of this study were 30 students at Al-Falah Kindergarten. The result of the sig.(2-tailed) effectiveness test shows that the android-based Orang Kayo Hitam Jambi folklore educational game increases students' motivation in the learning process.
The Implementation of Realistic Mathematics Learning in School (Phenomenological Study at State Junior High School 1 Manokwari)
Authors: Istia Maryo Sopater , Haryono Haryono , Utanto Yuli
Published: July 2023

This research method is a phenomenological study to describe the implementation of realistic mathematics learning in State Junior High School 1 Manokwari and to test the construction of mathematics teachers' perceptions of the meaning of realistic mathematics learning. This study uses observation, interview, and recording techniques to explore perceptions and implementations of realistic mathematics learning. The results showed that mathematics teachers at State Junior High School 1 Manokwari carried out realistic mathematics learning in a different way of perception. There is a tendency to apply the principles of realistic mathematics learning, using contextual questions that students can see, experience, or imagine to implement realistic mathematics learning in the classroom. In addition, another tendency is that teachers do not understand the concept of realistic mathematics learning, as evidenced by the lack of use of demonstration methods as motivational triggers in realizing students' mathematical ideas and concepts. Mathematics teachers need to be aware of themselves as facilitators of student learning because they build formal knowledge in a holistic and sustainable manner. This research shows that perception has a strong influence on certain decisions or actions.
Analysis of the Implementation of the Independent Curriculum in the Bina Insani Integrated Islamic Elementary School in Semarang City
Authors: Syah Hengki Firman , Wardani Sri , Suminar Tri
Published: July 2023

In order to recover after the pandemic COVID 19, the Indonesian government issued a curriculum change policy. My study aims to find out and understand the readiness of the implementation of the Independent Curriculum at Bina Insani Integrated Islamic Elementary School which is carried out by the principal, teachers and students. The implementation of the Independent Curriculum at Bina Insani Integrated Islamic Elementary School which is carried out by the principal, teachers and students, the outcomes of student learning class I and IV is in the form of learning outcomes and Pancasila Student Profiles on the implementation of the Independent Curriculum at Bina Insani Integrated Islamic Elementary School, and obstacles and solutions in implementing the Independent Curriculum at the Integrated Islamic Elementary School Bina Insani Semarang. This study uses a qualitative research method with a case study approach. Data collection techniques, namely observing school conditions and learning activities, interviewing the implementation of the independent curriculum, documentation studies. Data analysis techniques by examining all available data from various sources, data reduction, compiling reduced data, presenting data, and checking data validity. Based on the results of this study, the planning stage begins with accepting regulations from the government, establishing the school's vision, mission, and goals, preparing KOSP Bina Insani Integrated Islamic Elementary School, planning lessons, planning P5 activities. At the implementation stage of the curriculum, there are still some that have not been optimally implemented, such as learning activities that still need the teacher's understanding in differentiated learning. At the stage of evaluating the implementation of Bina Insani Integrated Islamic Elementary School which was carried out by the teacher, he had carried out a diagnostic to summative assessment. The results of this study can be used to add insight into the implementation of the independent curriculum in the learning process carried out by all components in schools using the independent curriculum .
Development of Power Point Macro-Based Interactive Multimedia in Learning Islamic Cultural History in Improving Student Learning Outcomes
Authors: Khasanah Hilda Amalia , Kustiono Kustiono , Samsudi Samsudi
Published: July 2023

The history of Islamic culture (SKI) learning process so far has taught teachers using conventional methods with minimal use of information technology which has an impact on low interest and student learning outcomes that are not in accordance with Article 19 paragraph 1 of Government Regulation No. 19 of 2005.This study aims to describe the learning characteristics of Islamic Cultural History in schools, develop learning media in the form of interactive learning multimedia, analyze the feasibility of SKI interactive learning multimedia, analyze SKI interactive learning multimedia in improving student learning outcomes. This type of research uses research and development (Research and Development) using the ADDIE model. The primary data collection technique is from the validation of media experts and material experts as well as the results of the pretest and posttest. The results of this study indicate that 1) SKI teachers teach in a teacher-centered way with the majority guided by LKS and SKI package books as learning resources, there are limitations to the use of media and technology where the media that is often used are blackboards and writing tools. 2) The results of the review by media experts and material experts state that the interactive multimedia based on PowerPoint macro enable that has been developed meets the criteria of being tested. 3) Development of interactive multimedia based on PowerPoint macro enable obtains very feasible criteria with an average percentage of 85.85%. 4) Interactive multimedia based on PowerPoint macro enable has a significant effect on student learning outcomes with the results of the small-scale hypothesis test obtaining 0.001 ≤ α 0.05 and the results of the hypothesis on a large scale obtaining 0.000 ≤ α 0.05. The gain test results on a small scale gets 0.7806 with high criteria and on a large scale gets 0.6187 with medium criteria.
Predictor Factors of Multi-Drug Resistance Tuberculose on the Characteristics of Chest Radiographic Lesions
Authors: Majdawati Ana , Habib Inayati
Published: July 2023

This research aimed to demonstrate some predictors of screening diagnosis of multi-drug-resistant tuberculosis (MDR-TB). Researchers determined several predictors as a screening diagnosis of MDR-TB, based on clinical symptoms, WHO criteria, chest radiographic lesions, and sputum smear microscopy. The method demonstrated a correlation between several factors as predictors of the MDR-TB diagnosis consisting of clinical symptoms, WHO criteria, BTA sputum, and cross-sectional chest radiograph lesions, based on examination of Gene X-pert for suspected MDR-TB. The results demonstrated a significant and positive odds ratio value of the relationship between variables: 1). Clinical symptoms (p:0.000) with the largest percentage of coughing with shortness of breath exhibiting 51.32% and coughing exhibiting 27.9%; 2). WHO criteria are among others, new patients (p:0.000; OR:3); 3). Chest radiographic lesion: consolidation (p: 0.000; OR: 3); pleural thickening (p:0.003; OR:2); Fibrosis (p:0.000; OR:6) with location on the medial right (p:0.000; OR:2) and left inferior (p:0.000; OR:3). The BTA sputum is (p:0.000; OR:8). The predictors for screening the diagnosis of MDR-TB are coughing, and shortness of breath. Other WHO criteria include radiographic lesions, fibrosis, consolidation, pleural thickening with the location of lesions either left inferior or medial right and positive smear sputum results.
Compliance with the Covid-19 Protocol for Pregnant Women in Pagelaran
Authors: Fauzia Parastika Anggun , Ratnawati Leersia Yusi , Sutjiati Rina
Published: July 2023

The COVID-19 pandemic resulted in more than 30 million deaths in 2020. Pregnant women are a vulnerable group. They tend to be at risk of contracting and experiencing complications that can affect pregnancy and fetal development. This research aims to analyze behavioral factors that influence compliance with the COVID-19 protocol for pregnant women using the health belief model approach in the working area of the Pagelaran Health Center. This research is a cross-sectional study of pregnant women in the Pagelaran health center. The sampling technique used in this study was random sampling and found 107 respondents. The analysis technique used in this study is multiple logistic regression. The research results show a significant influence between perceived susceptibility, perceived severity, perceived benefits, perceived barriers, and perceived self-efficacy with compliance. But there is no influence between cues to action on compliance. Variables included in the modeling and proven to influence pregnant women’s adherence to the COVID-19 protocol include perceived severity, perceived benefits, perceived barriers, and perceived self-efficacy, with perceived severity being the most dominant variable. So it is hoped that policy maker will consider more of perceived severity, benefits, barriers, and self-efficacy.
Analysis of Risk Factors for Commercial Sex Workers and the Prevalence of the Human Immunodeficiency Virus (HIV)
Authors: Widjaja Sajuni , Santosa Winnie Nirmala , Aditya Dwi Martha Nur
Published: July 2023

Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) are one of the biggest health problems in the 21st century. HIV/AIDS cases continue to soar, one of which is due to the practice of prostitution because commercial sex workers (CSW) are a group at high risk of contracting HIV/AIDS. Dolly, the largest localization at Surabaya, has already been closed by the government to decrease the transmission of HIV. The research method is based on laboratory examination using the Rapid Test Immunochromatography method, with the subject of examination being women who live around Dolly localization. This method has the advantages of fast inspection time (only around 15-30 minutes), is easy to do, do not use special tools, and is quite sensitive. The number of women who were HIV positive was 1.4%, and the numbers who were HIV negative was 98.6%. The association between the risk variables for CSWs and HIV status was then determined using the Spearman correlation test. Statistical analyses revealed a significant relationship between CSW status and HIV prevalence with a significance value of 0.05 (p=0.025; CI=95%). Since the correlation coefficient is positive, a rise in CSWs’ active status can also increase HIV prevalence.
Impact of PM10 Exposure and Socio-Demographic Aspect With Lung Function Disorders
Authors: Rachmawati Siti , Suryadi Iwan , Juherah Juherah , Rivai Abdur , Fitriani Nurlaila , Firmansyah Fathoni , Ratun Rina Zam
Published: July 2023

The concentration of PM2․5 and PM10 particles is a major problem and the primary environmental health risk that causes premature death. This study aims to examine the effect of PM10 exposure and socio-demographic aspects on lung function disorders of bus Terminal workers exposed to traffic emissions. This research used a cross-sectional approach. The population is 96 people, and 50 became samples according to the purposive sampling criteria. The measurement of lung vital capacity is by spirometry. The high-volume air sampler was applied to measure dust concentration, and the questionnaire was used to assess individual characteristics. The independent variables of this research are PM10 concentration, age, smoking behavior, working period, type of work, education, use of masks, and body weight. The dependent variable is impaired lung function. The bivariate analysis showed that exposure to PM10, smoking behavior, years of service, and use of masks were significant for impaired lung function. The result of multivariate analysis of dust is the most relevant to the lung vital capacity. In conclusion, dust concentrations are classified above the Threshold Limit Value (TLV), so government should control the source of dust exposure.
Chemical modification effect on the mechanical properties of HIPS/coconut fiber composites
Authors: Carvalho Kelly C. C. , Mulinari Daniella R. , Voorwald Herman J. C. , Cioffi Maria O. H.
Published: July 2023

Lignocellulosic fibers from green coconut fruit were treated with alkaline solution (NaOH 10%m/v) and then bleached with sodium chlorite (NaClO2) and acetic acid (CH3COOH). Alkali-treated and bleached fibers were mixed with high impact polystyrene (HIPS) and placed in an injector chamber in order to obtain specimens for tensile tests. Specimens of HIPS/alkali-treated and bleached coconut fiber composites were tested in tensile mode, and the fracture surfaces of the composites were analyzed by scanning electron microscopy. Untreated, alkali-treated, and bleached coconut fibers were analyzed by scanning electron microscopy and X-ray diffraction. Alkaline treatment was effective for removing the extractives and increasing the roughness of surfaces, while the bleaching treatment intensified the effect of alkaline treatment, while increasing the crystallinity index and surface energy of fibers. Results of tensile tests showed that the addition of 30% alkali-treated and bleached fibers reinforcing the HIPS matrix provided considerable changes in the mechanical properties of composites in comparison with the pure HIPS. On the other hand, chemical treatments were not totally effective for improving the adhesion between the fiber and matrix, as was observed in the analysis of the fracture surfaces of composites materials.
A Systematic Review of the Stress-Coping Scales Used in Korean Nursing
Authors: Ju Hyeon Ok , Park So Yeon , Lee Jaeyoung , Park Hye-Ryeon
Published: July 2023

This study aimed to compare the stress-coping measurement scales used in the nursing field in South Korea through a literature review based on the types of tools assessed, their characteristics, frequency of use, target stress, target population, and coping outcomes.The data base periodical information academic, Korea citation index, Korean studies information sharing service, Korean medical database, National discovery for science leaders, KoreaMed, National assemble library, and National library of Korea databases were searched for articles related to coping with stress and nursing published between 2009 and 2018 in South Korea. Of the total 1,666 articles searched, 59 articles that were aligned with the study purpose were finally selected after reviewing the original texts and excluding duplicates.The study identified six stress-coping scales used by Korean nurses, among which the ways of coping (WCQ) was the most frequently used. Most of the studies involved nursing students, followed by patients and health workers (nurses and caregivers). Regarding the types of stress, the WCQ was used the most by studies on work-related and daily living stress, followed by those focusing on health-related stress and clinical practice stress. Secondary analysis of WCQ usage showed that 48.5% of the studies interpreted the scale results for individual coping methods, and the remaining 45.5% interpreted the results based on the overall score.Researchers need to appropriately use and interpret the results of scales that have been translated into Korean and validated for each situation and participant.
Associated Factors with Changes of Metabolic Abnormalities among General Population in COVID-19 Pandemic
Authors: Kwon Eunjoo , Nah Eun-Hee , Kim Suyoung , Cho Seon , Park Hyeran
Published: July 2023

The coronavirus disease-2019 (COVID-19) pandemic has led to restrictions on daily living including social distancing. These restrictions had an impact on the individual's healthy lifestyle and health status. We investigated the associated factors with changes of metabolic abnormalities among general population in COVID-19.The participants were 43,639 people who received health check-ups twice in 2019 and 2021 during COVID-19 pandemic, at 16 health promotion centers. Metabolic abnormalities were identified according to the third report of the cholesterol education program criteria. Multiple logistic regression analysis was performed to confirm the factors related to changes of metabolic abnormalities during COVID-19.Metabolic syndrome and metabolic abnormalities increased overall during the COVID-19 pandemic. This increase was mostly appeared in males. The occurrence of metabolic syndrome during COVID-19 was associated with 50s and older age (odds ratio [OR], 1.130; 95% confidence interval [CI], 1.019-1.254), attempt to quit smoking (OR, 1.467; 95% CI, 1.171-1.839), start smoking (OR, 1.251; 95% CI, 1.110-1.412), decrease in aerobic exercise (OR, 1.328; 95% CI, 1.162-1.517), and increase in strength exercise (OR, 0.704; 95% CI, 0.592-0.838).The metabolic syndrome is closely related to smoking experience and lack of exercise during COVID-19.
Self-Efficacy and Self-Care Behavior in Patients with Unruptured Intracranial Aneurysm after Treatment with Coil Embolization
Authors: Shin Hyun Song , Kim Jeong Hye
Published: July 2023

This study aimed to identify the self-efficacy and self-care behaviors in patients with an unruptured intracranial aneurysm who have undergone coil embolization.A cross-sectional study was conducted to 143 patients who were diagnosed with unruptured intracranial aneurysm and visited the outpatient department of radiology for follow-up management after performing coil embolization at a tertiary hospital, Seoul. The self-efficacy and self-care behaviors were measured using self-reported questionnaire. The collected data were analyzed with independent t-test, one-way analysis of variance, Pearson's correlation using the SPSS/win 26.0 statistical programs (IBM Corp, Armonk, NY, USA).The mean score of self-efficacy in patients with an unruptured intracranial aneurysm was 3.49±0.55 out of 5. The mean score of self-care behaviors was 3.69±0.66 out of 5. The self-efficacy exhibited statistically significant differences depending on the size and number of the cerebral aneurysms and the presence of such aneurysms remaining after treatment. There was a positive correlation between self-efficacy and self-care behaviors (r=0.37, P=0.001). Regression analysis revealed that the patient's self-care behaviors of the patients was explained by self-efficacy (β=0.37, P<0.001) and these variables explained 13.3% of the variance in self-care behaviors (F=22.86, P<0.001).In order to increase self-care behaviors, it is necessary to develop self-efficacy interventions so that an unruptured intracranial aneurysm who have undergone coil embolization can effectively cope with various difficulties during treatment course.
Вплив спікання в умовах високих температур і тиску та механохімічного синтезу на кристалічну структуру монокарбідів TiC, ZrC, HfC
Authors: Білявина Н.М. , Туркевич В.З. , Курилюк А.М. , Стратійчук Д.А. , Наконечна О.І. , Когутюк П.П. , Стасюк Л.П.
Published: July 2023

Методом рентгенівської дифракції вивчено фазовий склад продуктів HPHT спікання (7,7 ГПа, 1600—2450 °С) систем cBN—TiC—Al, cBN—ZrC—Al та cBN—HfC—Al (об’ємне співвідношення компонентів шихти 60 : 35 : 5). Встановлено, що твердофазні реакції в цих системах ініціюються за температур баротермічної обробки, вищих за 2000 °С, і спричинюють утворення боридів відповідного металу (MeB2) та AlN. На основі рентгеноструктурних розрахунків кристалічної структури окремих фазових складових показано, що за високих температур HPHT спікання бориди MeB2 розчиняють невелику кількість алюмінію, а вихідні монокарбіди MeC перетворюються в карбіди MeCʹ, які в дійсності являють собою тверді розчини Me1–xAlxC, що містять до ≈8, ≈7 та ≈6 ат. % Al для TiC, ZrC та HfC відповідно. Механізм накопичення алюмінію в металевій підґратці твердих розчинів Me1–xAlxC здійснюється через попереднє утворення в структурах вихідних карбідів MeC вакансій, кількість яких корелює зі значенням ентальпії утворення цих карбідів.