bluuebunny/crossref_metadata_2025 huggingface dataset:
Feasibility study and preliminary design of Bataan–Cavite interlink bridge, Philippines
Authors: Yip Sammy , Hussain Naeem
Published: April 2022

The Bataan–Cavite interlink bridge (BCIB) is a proposed 32 km sea-crossing bridge at the mouth of Manila Bay, Philippines. The BCIB will connect Bataan to Cavite in order to unlock opportunities for economic growth and expansion outside Metro Manila. It comprises land viaducts, marine viaducts and two cable-stayed navigation bridges of 400 m and 900 m spans. The BCIC has to cater for extreme conditions of deep water, seismicity, typhoons and ship impact. Feasibility studies, the preliminary design of the link and how the bridge options were assessed in order to achieve an optimum solution are described in this paper.
Analysis of long-term temperatures inside tunnels during winter in Gangwon, South Korea
Authors: Chhun Kean Thai , Keo Sam-Ang , Jun Kyung-Jae , Yune Chan-Young
Published: April 2022

Tunnels are among the main components of transport infrastructure systems and as such must be protected against damage. As damage is particularly prevalent in cold climates, tunnels in Gangwon province, the coldest region of South Korea, were investigated in this research. The temperatures inside three tunnels (one short tunnel and two medium-length tunnels) were measured during the winter season (November to March) using iButton sensors installed on the surface of the tunnel linings at a height of 2 m from the ground. The long-term temperature data measured in this way were analysed and the results showed that January was the coldest month. The minimum and maximum daily air temperatures most frequently appeared during 3–6 a.m. and 2–4 p.m., respectively. The highest temperature gradient was found to occur 30 m from the entrance or exit. The temperatures inside the tunnels were significantly affected by external wind induced by vehicle traffic volumes compared with the natural wind direction, the wind velocity and rainfall. It is concluded that tunnel damage caused by frost heave and freeze–thaw action can be reduced by frequent inspection and evaluation.
On the interpretation and distribution of embedded main clause syntax: new perspectives on complex discourse moves
Authors: Djärv Kajsa
Published: April 2022

This paper examines the hypothesis that embedded Verb Second (EV2), a classic main clause phenomenon, is licensed by assertion. Based on detailed examination of naturally occurring data from Swedish, I address two central questions in the study of EV2: the interpretation of V2-complements, and the role of the matrix predicate in licensing V2-complements. I propose that the interpretation of EV2-clauses is best characterized in terms of the statement that they share the conventional discourse effects associated with matrix declaratives, in the sense of Farkas & Roelofsen (2017). At their core, EV2-clauses represent discourse moves whereby the speaker adds the embedded proposition to the conversational table as an issue for discussion. In many cases, this is accompanied by the speaker expressing a public commitment to this proposition, as in matrix assertions. However, I also identify cases that involve a commitment shift, where the assertion gets anchored not to the speaker, but to a contextually specified commitment anchor, which is identified by the matrix clause (but which does not need to correspond to the matrix subject, contrary to previous proposals). This allows the speaker to raise the issue represented by the EV2-clause at the level of the current conversation with the force of an assertion, without committing to the proposal it represents. Thus, the speaker can immediately reject or take issue with it. In addition to these assertive uses, I identify cases where the EV2-clause does not represent an assertive discourse move at all, but functions as a type of biased question. Such cases are similar in both function and form to (unembedded) rising declaratives, and are problematic for previous theories of EV2-licensing. With respect to the role of the matrix clause, I show that its key role is to appropriately frame the discourse move represented by the EV2- clause, in terms of its specific pragmatic effects. This work also has consequences for theories of clausal embedding more broadly, as it shows that such theories need to address the issue of how the discourse effects associated with different sentence types are able to project from the embedded level in a complex expression, to the level of the discourse.
Design of Electronic Voting System for Visually Impaired Persons Using Arduino Mega 2560
Authors: Choki Dema , Penjor Tshering , Phuntsho Tashi , Rai Dhan Kumar , Muramatsu Kazuhiro
Published: April 2022

People with visual impairment, even if they are availed to voting, they do not have the privilege to vote confidentially, because of their physical disability. Therefore, a user-friendly and confidential voting system is necessary for visually impaired people. In this paper, we build an electronic voting system for visually impaired people is a user-friendly device which can help those group of people vote independently with sound. The system is built on an Arduino Mega 2560 microcontroller board, a SD card module, an LCD module, several buttons, a buzzer, GSM SIM 900A and a headset. The system has a special voice feature stored in SD card to familiarize them with names of candidates. Also, the voice is passed through a headset for secrecy. In addition, a control unit of the system for polling officials is designed separately from a voting unit for the smooth election procedural. Once user votes, a buzzer is turned on and the system cannot accept the voting. If a control button is pushed, the buzzer is turned off and the system accepts voting. This mechanism is to avoid double voting. A result button is implemented to display final votes for each candidate and store them in the SD card. GSM SIM900A is interfaced with Arduino Mega 2560 to disseminate final results. We can encourage mass participation equally in democracy through the system electronic voting system.
Astrocytes and human artificial blood-brain barrier models
Authors: Zidarič Tanja , Gradišnik Lidija , Velnar Tomaž
Published: April 2022

The blood-brain barrier (BBB) functions as a highly selective border of endothelial cells, protecting the central nervous system from potentially harmful substances by selectively controlling the entry of cells and molecules, including components of the immune system. To study the BBB properties, find suitable therapies, and identify new drug targets, there is a need to develop representative in vitro BBB models. In this article, we describe the astrocyte roles in the BBB functioning and human in vitro BBB models.
[RETRACTED] PureFit Keto Pills Reviews 2022 Over the last decade, the ketogenic diet has advanced from borderline to mainstream. As a result, a whole assiduity has been erected up around keto1. There are now relatively a many products on the request that claim t v1
Authors: Keto Pills Reviews Express
Published: April 2022

[RETRACTED]

Publish Warning2title(s)3Protocol abstract4Set authors5Status6Research study7Add workspaces8Publish "PureFit Keto Pills Reviews 2022
eDNA extraction with kaneka v1
Authors: Xia Fei
Published: April 2022

We used the Kaneka Simple DNA Extraction Kit version 2 (Kaneka) for on-site DNA extraction from Sterivex. We injected 500µl of Solution A of the kit into the Sterivex and shook it by hand for 1min. We collected the Solution A buffer in the Sterivex by connecting the syringe with the connecting tube. We added 70µl of Solution B into the collected Solution A buffer in a 1.5-ml microtube and centrifuged (~2,000g) with a portable centrifuge for 3min. We collected 200µl of the supernatant solution.
[RETRACTED] Nucentix Keto X3 Reviews - Does It Really Works? v1
Authors: not provided nucentixketoreviews
Published: April 2022

[RETRACTED]

Nucentix Keto X3 Reviews - Does It Really Works?
A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase v2
Authors: W W Chomczynski Peter , M Vires Kianna , Rymascewski Michal , A. Heiny Judith
Published: April 2022

The highly conserved, cardiotonic steroid binding site (also termed ouabain binding site) on the primary α subunit of Na,K-ATPase plays a receptor signaling role in a range of vital cell processes and is a therapeutic target for human disease. Mouse lines with altered affinity for cardiotonic steroids on the α1 or α2 subunit isoform of Na,K-ATPase, without any change in pump activity, were developed by the late Jerry B Lingrel and are a valuable tool for studying its physiological roles and drug actions. In one model, the normally ouabain resistant α1 isoform was rendered sensitive to ouabain binding. In a second model, the normally sensitive α2 isoform was rendered resistant to ouabain binding. Additional useful models are obtained by mating these mice. To further advance their use, we developed a rapid, real-time PCR method that detects mutant alleles using specific primers and fluorescent probes. PCR is performed in fast mode with up to 15 samples processed in 40 min. The method was validated by Sanger sequencing using mice of known genotype, and by comparing results with a previous two-step method that used PCR amplification followed by gel electrophoresis. In addition, we clarified inconsistencies in published sequences, updated numbering to current reference sequences, and confirmed the continued presence of the mutations in the colony. It is expected that a wider availability of these models and a more efficient genotyping protocol will advance studies of the Na,K-ATPase and its cardiotonic steroid receptor.
Dynamic reliability evaluation of buried corroded pipeline under rockfall impact
Authors: Wang Yifei , Xie Mingjiang , Su Chun
Published: April 2022

Load impact, such as the rockfall, may bring significant threats to the integrity management of pipeline. This study is intended to evaluate the reliability of buried pipeline under rockfall impact, and so as to reduce the possible failure and unnecessary downtime. Firstly, the dynamic response of the buried pipeline under load is analyzed by Euler Bernoulli foundation beam. After that, the process of rockfall impact on buried corroded pipeline is simulated with nonlinear finite element method. Furthermore, the influence of rockfall’s parameters (including rockfall mass, impact velocity, impact position, etc.) on the pipeline’s equivalent stress is quantitatively analyzed. Eventually, a time-varying reliability model is established to calculate the failure probability. The results indicate that the mass and velocity of the rockfall have obvious influence on the pipeline’s failure probability, and the change of impact’s position has small influence. The proposed method can provide a theoretical reference for the design and maintenance of buried pipeline.
Recuerdos del futuro. Derivas mediales ante la obsolescencia tecnológica entre el cine y la fotografía.
Authors: Luna Lozano Sergio
Published: April 2022

En el presente texto realizamos una revisión acerca de los condicionantes que dieron lugar a la invención del tiempo cinemático durante la modernidad, poniendo en valor la labor que tuvo la cronofotografía en el estudio de la desfragmentación del movimiento y la importancia de los aparatos fotográficos que posibilitaron su desarrollo. El diseño de estos dispositivos se basa generalmente en el ensamblaje de mecanismos relativamente sencillos que dan lugar a instrumentos más complejos, y se realiza bajo una aptitud que conecta con la figura del bricoleur definida por Lévi-Strauss y que hemos entroncado con algunas prácticas contemporáneas que se desarrollan en el ámbito de la arqueología de los medios. Finalmente, presentamos un estudio de caso donde se describe desde un punto de vista práctico el desarrollo de un dispositivo de registro y proyección de imagen, a medio camino entre la fotografía y la imagen en movimiento, realizado a partir de la modificación y recuperación de medios obsoletos, en un intento por indagar las vías alternativas a los modelos de continuidad de la historia de los medios.
ÇOCUKLARIN DUYGU DÜZENLEME BECERİLERİ VE PROBLEM DAVRANIŞLARI İLE ÖĞRETMEN VE EBEVEYNLERİNİN DUYGU DÜZENLEME VE ÖĞRETMENLERİN SINIF YÖNETİMİ BECERİLERİ ARASINDAKİ İLİŞKİNİN İNCELENMESİ
Authors: Kara İdris , Dikici Sığırtmaç Ayperi
Published: April 2022

Bu araştırmanın amacı; okul öncesi dönem çocuklarının duygu düzenleme becerileri ve problem davranışları ile öğretmen ve ebeveynlerin duygu düzenleme becerileri ve öğretmenlerin sınıf yönetimi becerileri arasındaki ilişkinin incelenmesidir. Araştırma nicel araştırma yöntemlerinden ilişkisel tarama modelindedir. Araştırmanın örneklemini Millî Eğitim Bakanlığına bağlı Siirt il merkezindeki resmi veya özel okul öncesi eğitim kurumlarında çalışan 142 okul öncesi öğretmeni ile öğretmenlerin sınıfından basit rastgele örnekleme yöntemi ile seçilen 687 çocuk ve 618 ebeveyn oluşturmaktadır. Araştırmada nicel veri toplama aracı olarak öğretmenler ve çocuklar için ayrı hazırlanmış kişisel bilgi formu ile çocukların duygu düzenleme becerilerinin değerlendirilmesi amacıyla Çocuk Duygu Düzenleme Ölçeği, yetişkinler için bilişsel duygu düzenleme becerilerini ölçmek amacıyla Bilişsel Duygu Düzenleme Ölçeği, okul öncesi dönem çocuklarının problem davranış düzeyinin belirlenmesi amacıyla Problem Davranış Ölçeği ve öğretmenlerin sınıf yönetimi becerilerine ilişkin algılarını saptamak için ise Sınıf Yönetimi Beceri Düzeyi Ölçeği kullanılmıştır. Araştırmadan elde edilen bulgulara göre öğretmenlerin bilişsel duygu düzenleme becerileri ile sınıf yönetimi becerilerinin pozitif yönlü ilişkiye sahip olduğu ve bilişsel duygu düzenleme becerilerinin sınıf yönetimi becerilerini yordadığı belirlenmiştir. Ayrıca ebeveynlerin bilişsel duygu düzenleme becerileri ile çocukların problem davranışları arasında ilişki olduğu sonucuna varılmıştır. Çocukların duygu düzenleme becerileri ile problem davranışları arasında ilişki tespit edilmiş ve duygu düzenleme becerilerinin problem davranışları yordadığı bulunmuştur.
Dermoscopic Patterns of Onychomycosis:
A Cross-sectional Study in One Institution
Authors: Lee Kyung Jae , Kim Jung Eun
Published: April 2022

Background: Several dermoscopic findings that could be helpful in diagnosing onychomycosis have been reported
in many cases, but they have not been sufficiently utilized in clinical practice.
Objective: To evaluate and identify the dermoscopic findings that may assist in the accurate diagnose of
onychomycosis.
Methods: The study included 42 patients with clinical features suggestive of onychomycosis based on the clinical
history, physical examination, dermoscopic findings, and mycological investigation. Clinical photographs and nail
dermoscopy images were obtained, which were retrospectively reviewed and analyzed according to the onychomycosis
classification.
Results: In total, 42 representative nails were reviewed. Common dermoscopic patterns such as yellow/brown
discoloration and subungual hyperkeratosis were found in our onychomycosis patients. Key findings observed in
specific subtypes were distolateral subungual onychomycosis with "jagged edges with spikes", proximal subungual
onychomycosis or white superficial onychomycosis with irregularly bordered homogeneous leukonychia with
postinflammatory hyperpigmentation on the proximal nail fold, and fungal melanonychia with nail plate roughness
and nail fold hyperkeratosis.
Conclusion: Our study, along with previous studies, demonstrated dermoscopy as a quick and effective tool for
diagnosing onychomycosis. In addition, periungual dermoscopic findings can be an important clue in onychomycosis
diagnosis, especially in cases of fungal melanonychia and leukonychia.
Vinca Hybrids with Antiproliferative Effect
Authors: Mayer Szabolcs , Keglevich Péter , Hazai László
Published: April 2022

Vinca alkaloids used in anticancer therapy are the well-known vinblastine and vincristine as classical antitumor agents. These dimeric molecules consist of two monomers, vindoline and catharanthine, which have no particular activity on their own. The goal in our research work was to obtain derivatives of one of these, vindoline, resulted in molecules with important antiproliferative effect. This type of derivatives were hybrids; vindoline was conjugated with several pharmacophores with and/or without linkers. Pharmacophores were amino acid esters, steroids, triazoles, and flavones. In several cases, the synthesized compounds showed on some cell lines an even better effect than vinblastine.
Mediastinal Adenopathy After COVID-19 Infection
Authors: Greywal Kaveer , Greene Nelson , Kashyap Rahul , Surani Salim
Published: April 2022

Since the outbreak of the COVID-19 pandemic, there have been myriad signs and symptoms ascribed to this disease process. While some of the most notable features described since the initial months of the pandemic include cough, fever, myalgia, headache, dyspnea/hypoxia, anosmia, and multifocal pneumonia, the pandemic’s prolonged continuation has afforded ample opportunity to detect more subtle signs of the disease. Mediastinal adenopathy is one such sign that has been found in many patients with active COVID-19 infection, though the value of this finding in both prognostication and guiding treatment remains unknown. We did a timely brief review of mediastinal adenopathy in COVID-19 infection to shed more light on the potential implications of this finding. We conclude that Mediastinal Adenopathy in hospitalized COVID-19 patients has been associated with higher ICU admissions and higher mortality. Its non-specific nature and confounding etiology may prevent it from being a good marker for prognosticator of COVID-19 disease severity.
Validating Lyfas as a reliable mental health screening and monitoring instrument: a step towards mobile health application during COVID-19 Pandemic
Authors: Chattopadhyay Subhagata , Das Rupam
Published: April 2022

COVID-19 has disturbed mental health to a great extent. Lockdowns, re-infections in fully vaccinated people, frequent mutations of the virus, working from home, shutting of school colleges, contradictory information flying in the air, and so on are some serious predisposing factors in deteriorating the mental health. The Indian Govt. has granted the telemedicine model of healthcare in the country. Mobile health (mHealth) adds to it effectively and Lyfas is such a smartphone-based instrument that works using the principle of arterial photoplethysmography and photochromatography. It captures short (120 sec) heart rate variability (HRV) and the allied optical biomarkers that surrogate for the cardiovascular autonomic modulation, which is influenced by mental health issues. The study aims to validate Lyfas optical biomarkers (SD1/SD2, LF/HF, pNN50, and HRVscores) and a set of physical parameters e.g., age, HR, BP – systolic and diastolic, and serum cortisol in addressing the mental health state. A total of RTPCR positive 1130 adults (Male 541, Female 589) within the age group of 27-68 yrs. participated in the study. Till the participants became RTPCR negative (average time of 14 days), the Depression-Anxiety-Stress Screening-21 (DASS-21) and Covid Screening Scale (CSS)-based monitoring is done once daily to note the distress levels, and Lyfas tests are taken thrice daily simultaneously. The average of all scores constructs the experimental data. Internal consistency (Cronbach’s α), normality test (Shapiro Wilkis test), and Spearman’s correlations (ρ) and their respective statistical significance (p<0.05, CI: 95%) are computed. The study concludes that Lyfas biomarkers show strong correlations with that of the DASS-21 and CSS scores. Physical parameters are also corroborative to the result.
Correlation of Pathological Manifestations in Covid 19 Positive Cases Complicated by Either Isolated Mucormycosis or Co-Infection with Other Fungi: Experiences of a Tertiary Level Institute
Authors: Jaiswal Riddhi , Malhotra H S , Himanshu D
Published: April 2022

As a part of multi-disciplinary team of the institute in managing Covid positive patients as well as those admitted with its complications, Pathology department was reporting specimens of suspected fungal infection, received from clinical departments like neurosurgery, otorhinolaryngology, ophthalmology, oral and maxillofacial surgery, respiratory medicine, internal medicine etc. Simultaneous serology and various Covid associated blood parameters were being investigated during admission to hospital, as per the clinical scenario. The aim of this paper is to discuss pathogenesis of fungal infections and bring out any significant pathological differences in Covid 19 positive cases afflicted subsequently by either mucor alone or mixed fungal infections. Out of 274 tissue specimens received between April to November 2021, clinically suspected to be of Covid 19 associated mucormycosis, we found 14 cases of simultaneous co-infection with other species of fungi. 45 specimens were reported negative for fungal elements while 229 were confirmed by histo pathological examination. Cases were grouped according to the presence of either only Mucormycosis on histology or mucor with co-infecting fungi.Various biochemical, hematological and histopathological parameters were compared and significance of difference analysed using student t test in the two groups. Statistically significant differnce was observed in mean values of serum ferritin (p value 0.005); C-Reactive Protein/CRP (p value 0.003); serum creatinine, Random Blood Sugar/RBS, Haemoglobin, Total Leuocyte Count/TLC and duration of hospital stay (p value of each being 0.00) while p value was insignificant in serum Lactate Dehydrogenase/LDH and InterLeukin 6/IL6 values between the two groups. Platelet count of patients in both the groups were within normal range. (1-4.5 x1000/cu mm). None of the Histopathological parameters showed any statistically significant difference in the two groups (p value of each was more than 0.05).
Biobetters: Are They Truly Better?
Authors: Zaveri Rohan , Asher Shreya , Priefer Ronny
Published: April 2022

Biologics have seen an explosion in application for a myriad of diseases. Recently the term “biobetter” has entered the lexicon of the pharmaceutical industry. This marketing term refers to a drug that is supposedly a “better” version of a reference biologic. By this definition, these biologics must invariably have some improved pharmacologic and/or pharmacokinetic parameters, such as a better safety/efficacy profile. In actuality, this is not necessarily the case. Additionally, to-date there is neither a legal nor regulatory pathway in place for the development of said, biobetters. This lack of any classification has led to its inconsistent and often inaccurate use within scientific literature. To rectify this, a framework for the potential correct use of the term biobetter within scientific literature (not regulatory) has been provided. Additionally, an exhaustive reclassification of any drug that have been previously termed “biobetter” has been conducted. We believe this classification system, specifically: true-biobetter, potential-biobetter, or non-biobetter will prevent further misuse of the term in the scientific community without modifying the clinical application of such biological entities in practice and in research.
Retrospective analysis of COVID-19 patients in the region of Eastern Achaia, Greece, in a Primary and Secondary Healthcare Setting. Could initial laboratory findings and age prejudge patients’ outcome?
Authors: Xaplanteri Panagiota , Zoitopoulos Vasileios , Diamanti Vasiliki , Moutafidi Athanasia , Masoura Panagiota , Potsios Charalampos , Filioti Konstantina , Rapanou Angeliki , Koutsouri Christina-Panagiota , Grammenidou Zoi , Tzoudas Aimilios , Sakarelou Chara , Rokaj Tatiana , Ntzinia Katerina , Martinez Elsa , Papachristopoulos Georgios , Letsas Constantinos
Published: April 2022

Since December 2019 mankind is agonized over the deadly coronavirus disease 2019 (COVID-19) which is due to the novel coronavirus (2019-nCoV) or Severe Acute Respiratory Syndrome Coronavirus-2 (Sars-cov-2). Methods: In this retrospective study, laboratory findings and demographic features form all confirmed COVID-19 patients who attended the Emergency Department of both branches of our hospital during the first semester of 2021 were collected and analyzed. The working hypothesis was that initial laboratory data at the time the patients seeked medical assistant for the first time, regardless of comorbidities and day of onset of symptoms, can help predict patients’ outcome. Demographic data and laboratory tests were compared between hospitalized and non-hospitalized patients. Results: Data of 270 patients were collected and analyzed retrospectively. 31 blood measurement parameters performed in both hospital branches were compared between hospitalized and non-hospitalized patients. Of those, WBC count (p=0.016), neutrophil percentage (p<0.001), lymphocyte percentage (p<0.001), platelet count (p=0.041), glucose (p<0.001), urea (p<0.001), creatinine (p<0.001), SGOT (p=0.024), CK (p<0.053), LDH (p<0.001), GGT (p<0.001), sodium (p<0.001), calcium (p<0.001), high sensitivity Troponin I (p<0.001), and ferritin levels (p<0.001), proved statistically significant. Regarding demographic data, age was significantly linked to patients’ survival. Conclusion: Our data suggest that common initial laboratory findings of COVID-19 patients who seek for the first-time medical assistant regardless of comorbidities and time from onset of symptoms can give clues to the patient outcome. Age is also important for patients’ survival. Especially in a Primary Health Care Setting, common blood parameters like WBC count, neutrophil and lymphocyte percentage, platelet count, glucose, urea, creatinine, SGOT, CK, LDH, GGT, sodium, calcium, high sensitivity Troponin I, and ferritin levels, could be really helpful to predict disease severity.
A Model of Post-Traumatic Stress Disorders and Dissociative Identity Disorder from the perspective of Social Emotions
Authors: Fontana Alessandro
Published: April 2022

Post-Traumatic Stress Disorder, Complex Post-Traumatic Stress Disorder and Dissociative Identity Disorder are conditions caused by exposure to one or more stressful events of extraordinary magnitude and/or repeated over many years. The traumatic experience(s) may have different outcomes in different persons: some people fully recover within a short time, while others go on to develop one of these three disorders, whose interdependencies are still poorly understood. The present work utilises an updated version of a model of mental functioning, that has been previously applied to schizophrenia, to provide an interpretation of the aforementioned conditions. The model, built through the method of Artificial Life and with the toolset of Artificial Intelligence, foresees that the mind is subject to two forces: trauma, which represents the attack on the mind, and dissociation, which embodies the mind defence in both physiological and pathological conditions. The balance between these forces determines the pathological outcome.
Dual migration of organic foreign body in bronchus
Authors: Bhardwaj Abhishek , Malhotra Manu , Nongthombam Surjalata Devi , Priya Madhu , Sood Rachit
Published: April 2022

The foreign body in the bronchus is one of the most fatal emergencies in the Otorhinolaryngology. Delay in the appropriate treatment may result in acute airway diseases and fatal complications. The aim of this manuscript is to report a clinical case of dual migration of an organic foreign body from left to right and then back to the left bronchus in a 13 months old child. The case was initially diagnosed as left sided severe pneumonia which recurred after initial partial response to medical management and thus raised the suspicion of a foreign body. Computed tomography of the chest revealed a foreign body in the right bronchus contrary to clinical findings on the left side suggesting the first migration. The foreign body was visualized and removed from the left bronchus during bronchoscopy; which was contrary to radiological findings, suggesting the second migration.
A unilateral popliteal vein aneurysm in an adult cadaver: A case report
Authors: K Kiruthika Shree , Varma Aditya , Ramachandran Kalpana
Published: April 2022

The incidence of venous aneurysm is less than the arterial aneurysms. The knowledge of Popliteal vein aneurysm (PVA) is important as it could be a source of pulmonary embolism, deep vein thrombosis and so could be fatal. PVA could be an incidental finding during the investigations for pulmonary embolism or chronic venous insufficiency.

We report a case of left popliteal vein aneurysm in the popliteal fossa in a 65-year-old female cadaver observed during routine dissection. A large saccular dilatation was noted in the left popliteal vein in the distal part of the popliteal fossa. The right popliteal vein was normal.

An early diagnosis of PVA with doppler ultrasound examination is important to prevent the occurrence of any thromboembolic events or other major complications.
Aphasia, apraxia, and dysphagia following viper envenomation: A single case report
Authors: Rani R Johnsi
Published: April 2022

: Aim of the work was to highlight unusual complications such as aphasia, apraxia and dysphagia following viper bite.

In this case report, a 55 years old male who had developed Cerebrovascular Accident (CVA) and Right hemiparesis after an hour of saw-scaled viper bite on his right foot was described. His MRI report revealed chronic infarct in bilateral fronto parietal lobe. Difficulty in speaking and swallowing were observed and the patient was under nasogastric feeding. For assessing speech and language skills, Western Aphasia Battery and Apraxia Battery for Adults-2 was used. Manipal Manual for Swallowing Assessment was used for assessing the swallowing skills.

: The assessment results indicated that the patient had Broca’s aphasia with Non-Verbal oral apraxia and oropharyngeal dysphagia. Improvement was observed in swallowing and verbal communication skills following speech-language intervention.

Aphasia, apraxia and dysphagia were unusual complications following viper bite. Therefore, it is important for a speech language pathologist to have knowledge regarding various causes of stroke for better speech, language and swallowing management
A rare case report- foreign body of submandibular gland
Authors: Datta Ginni , Shaikh Faiz Zubair
Published: April 2022

Foreign bodies of submandibular gland are rare but consistently reported. They usually present as obstructive submandibular sialadenitis. The diagnosis can be challenging because of rarity of such an event, and inability of traditional diagnostic methods to detect the foreign body. Due to its protected location under the mandible and only penetrating injuries to the floor of the mouth or trauma underneath the mandible can reach and damage it. Hence, submandibular gland injury is a very rare incidence that has been documented only in case reports.

To approach an early diagnosis, a patient history needs to be believed. In this case report we will highlight the diagnostic and treatment challenges the patients and the surgeons face in foreign bodies of submandibular gland.
Periostin: A Potential Biomarker and Therapeutic Target in Pulmonary Diseases
Authors: Alzobaidi Nafaa , Rehman Sana , Naqvi Maaz , Gulati Kavita , Ray Arunabha
Published: April 2022

Periostin is a matricellular, nonstructural protein belonging to the fasciclin family and is encoded by the POSTN gene in humans. Periostin plays an important role in maintaining a normal tissue matrix in the lungs. Despite the vital role as a structural mediator in tissue growth and repair, periostin is involved in the pathogenic mechanism during tissue remodeling and fibrosis. Periostin is a chemoattractant mediator, promotes eosinophil recruitment and adhesion on the airways sub-epithelial membrane of asthmatic patients. POSTN gene was identified as one of the highly expressed genes induced by interleukins IL-13, IL-5 and IL-4 - the key cytokines of Th2 immune responses in the bronchial tissues of asthmatic patients. This review highlights the potential role of periostin as a validated biomarker in respiratory disease progression and its candidacy to predict the response to treatments targeting Th-2 cytokines in bronchial asthma. In addition, its potential role in COPD, IPF, lung cancer and lung infection, is also speculated.
 
Keywords
Periostin, Asthma, Pneumonia, COPD, Idiopathic pulmonary fibrosis, Biomarker
Association Between Vitamin D Levels and Inflammatory Markers in COVID-19 Patients: A Meta-Analysis of Observational Studies
Authors: Hopefl Robert , Ben-Eltriki Mohamed , Deb Subrata
Published: April 2022

Purpose: Vitamin D has immunomodulatory properties that can be useful in COVID-19 patients. We performed a meta-analysis of observational studies to analyze the association of vitamin D levels with the inflammatory markers in COVID-19 patients. Methods: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), the Cochrane Database of Systematic Reviews, and ClinicalTrial.gov for any relevant studies with comparison data reporting vitamin D levels and inflammatory markers in COVID-19 patients. A literature search was conducted from December 1, 2019, to January 14, 2022. Vitamin D deficiency was defined by each individual study and ranged from <9.9 ng/mL to <30 ng/mL. The inflammatory markers of interest were interleukin-6 (IL-6), C-reactive protein (CRP), ferritin, procalcitonin, erythrocyte sedimentation rate (ESR), lactate dehydrogenase (LDH), fibrinogen and D-dimer. Weighted mean difference (WMD) and 95% confidence intervals (CIs) were pooled using random or fixed-effects models. Two independent investigators assessed study eligibility and synthesized the evidence. Results: Thirty-two observational studies were included comprising of 7,771 patients ranging from 40-81 years of age with 57.1% being male. Meta-analysis showed that patients that were vitamin D sufficient (levels >30ng/mL) had statistically significant lower levels of IL-6, CRP, ferritin, LDH, fibrinogen, and D-dimer compared to vitamin D deficient group. With the highest mean difference found in ferritin (95.62; 95% CI, 33.14-158.10); P=0.003; I2=99%). No significant reductions were found in ESR (P=0.97). All inflammatory markers analyzed were higher than the normal healthy reference ranges in both groups. Conclusions: Our results suggest that low vitamin D levels are associated with increased inflammatory marker levels. Vitamin D deficiency may potentially serve as an early identifier for COVID-19 patients at high risk of developing severe inflammatory conditions as well as thrombotic complications. Randomized controlled trials should be conducted to establish a causal relationship.
BRICOLAGE AND NON-SELECTION AS LANGUAGE STRATEGIES OF THE RAP GROUP "MUTANT KHVLAM"
Authors: VARLYGINA Mariia Yu.
Published: April 2022

The purpose of the article is to determine the features of the rap discourse as an original linguistic integral phenomenon of the XXI century, to characterize the language strategies of one of the underground Russian rap groups. The relevance of the work is due to the little research of rap as an artistic discursive formation. The object of the analysis is the texts of the rap group “Mutant Khvlam”. The subject of consideration is the linguistic features of poly code works, the use of postmodern principles in the organization of the band’s tracks. As a result of the study, a contextual correlation was established between the current cultural paradigm and the development of a new musical and verbal genre. A postmodern angle of view on the ideological and linguistic foundations of the existence of rap was involved, an assumption was given about the neo-mythological nature of the rap narrative. Conclusions: Rap is a single type of spoken discourse, regardless of the poetic or prose tradition; has a hybrid nature and a flexible structure that allows the subject of speech to act freely within the genre, to resort to language experiments and play. The creative heritage of the rap group “Mutant Khvlam” is characterized by the form-making principles of non-selection and bricolage, with the help of which the author’s neo-mythological world is constructed. Non-selection as the lack of consistency and completeness of the narrative manifests itself at the lexical, grammatical, and syntactic levels. The fragmentariness and illogic nature of speech constructions in the texts of the group disorient the recipient in the information space, forcing him to unsuccessfully think up potential inter-image connections, intentions of speech, and the axiology of a decentralized narrative. Bricolage as a tool “recycles” the fragments of cultural codes of various origins into an eclectic linguistic kaleidoscope, enhancing the effect of the chaos of non-selection, and creating a network of primary sources for multiple interpretations.
LEXEMES SOME AND ANY AS MARKERS OF THE CATEGORY OF DETERMINATION IN MODERN ENGLISH
Authors: MOISEIENKO Natalia G.
Published: April 2022

The article is aimed at establishing contextual and grammatical meaning of lexemes some and any as well as their grammatical characteristics. A hypothesis concerning the category of determination has been formulated. There was also made an attempt to define the possibility of the lexemes under analysis to function as markers of the above-mentioned category. The object of our scientific investigation is the category of determination and peculiarities of functioning of lexeme some and any in Modern English. The subject of our analysis is the character of the category of determination and the lexico-grammatical peculiarities of lexemes some and any which enable them to function as the markers of the category of determination. The results of our analysis show that according to their grammatical characteristics lexemes some and any belong to different parts of speech, but in the view of pragmatics they are united by the meaning of markers of indefiniteness, they are associated with unknown, indefinite, non-identified phenomenon which corresponds to semantics of the category of indefiniteness. Conclusions. Coming from the fact that the meaning of some and any completely corresponds to the semantics of the category of indefiniteness, they can be markers of this category. Their belonging to different discourse-cognitive groups of words makes it possible to suppose that grammatical markers of the category of determination are not limited by the frames of one part of speech.
PHRASEOLOGICAL PERIPHRASES AND EXPANDED METAPHORS IN THE TEXTS OF CONTEMPORARY POLISH PROSE
Authors: STEFANYSHYN Yuliia M.
Published: April 2022

The aim of the article is to study the features of the structure, semantics and functioning of phraseological paraphrases and expanded metaphors in the texts of modern Polish fiction. The object of the study — phraseological periphrases and expanded metaphors as types of phraseological transformations, the subject — their structural-semantic and functional-pragmatic features. The result of the study is a thorough analysis of the textual implementation of 53 phraseological paraphrases and 44 expanded metaphors identified in Polish fiction, elucidation of the mechanisms of their creation, classification, definition of semantic changes in comparison with normative units, demonstration of functions in the text. It is concluded that paraphrasing the idiom and expanding the metaphor have different effects on the meaning of phraseological unit. In the case of phraseological periphrasis, the indication of phraseologism occurs through its structural elements, introduced into the context remotely, paraphrased or descriptively. Some phraseological periphrases are characterized by a shift of semantic accents, accompanied by a transition of logical emphasis from one sema of the denotative meaning of a stable phrase to another. Those periphrases in which the shift of semantic accents does not occur, preserve the traditional sequence and hierarchy of elements of the idiom’s internal form. The use of phraseological metaphors is conditioned by an attempt to convey as accurately as possible those language elements that cannot be expressed in traditional way. These transformations help to metaphorize the context, “exploiting” a blurred internal form in order to express an opinion in a way that best fits the author’s intent. Transformations that consist in the realization of an element of the internal form outside the phraseological unit usually do not modify the traditional meaning of idiom in any way. In the case of continuity or correctionof the situation underlying the internal form of the phraseological unit, the influence on the semantic structure is noticeable. The practical value of the research results is the creation of a classification of phraseological periphrases and expanded metaphors that contribute to the further study of these phenomena
Accuracy Limits of Pair Distribution Function Analysis in Structural Characterization of Nanocrystalline Powders by X-ray Diffraction
Authors: BALOOCHİYAN Abolfazl , BATYROV Merdan , OZTURK Hande
Published: April 2022

We report the minimum errors of structural parameters, namely lattice parameter, crystallite size, and atomic displacement parameters, expected from Pair Distribution Function (PDF) analysis of nanocrystalline gold powders for the first time by a self-consistent computational methodology. Although PDF analysis has been increasingly used to characterize nanocrystalline powders by X-rays, the current literature includes no established error bounds to be expected from the resulting structural parameters. For accurate interpretation of X-ray diffraction data, these error bounds must be determined, and the obtained structural parameters must be cleared from them. Our novel methodology includes: 1) simulation of ideal powder diffraction experiments with the use of the Debye scattering equation, 2) pair distribution function analysis of the diffraction data with the Diffpy-CMI analysis software, and 3) determination of the errors from PDF analysis of the simulated diffraction data by comparing them with real-space analysis of spherical gold nanocrystals that are 30 nm size and smaller. Our results show that except for the lattice parameters and even with an ideal crystalline powder sample and ideal diffraction data, the extracted structural parameters from PDF analysis diverge from their true values for the studied nanopowder. These deviations are dependent on the average size of the nanocrystals and the energy of the X-rays selected for the diffraction experiments, where lower X-ray energies and small-sized nanocrystalline powders lead to greater errors.
Training a special teacher: Opinions and experience of teachers in the conditions of inclusive education
Authors: Bibigul Dyussenbayeva , Marina Kuznetsova , Alpysbayeva Madina , Nietbaeva Gulmira
Published: April 2022

In the context of the active spread of inclusive education in Kazakhstan, it seems important to modernize their training for work in inclusive schools. Accordingly, the problems of effective preparation of teachers to work with inclusive classes have acquired particular relevance. The aim of the proposed study was a comparative study of the opinions of teachers-defectologists in secondary schools of the region on the organization and implementation of practice in inclusive education.  Thus, an interview was conducted with teachers in North Kazakhstan. The development of inclusively oriented professional and personal competencies among teachers largely depends on the success of the inclusion of children with special educational needs in the general educational process. Based on the study of the opinion of special teachers practicing in inclusive organizations, it is argued that inclusive education of children with special educational needs requires a change in approaches to the training of special teachers, modernization of the content, and directions of their training.

 

Keywords:  Defectologists; inclusive education; special educational needs; teacher training.
The technology of criterion assessment of students' knowledge in geography lessons
Authors: Kalkashev Sagyngali , Nurbol Ussenov , Abdimanapov Bakhadurkhan , Kaimuldinova Kulyash , Ayapbekova Aliya , Nurhanov Margulan
Published: April 2022

The study aims to get the views of teachers about the difficulties encountered in online education in the evaluation of students' knowledge in geography lessons with criterion assessment technology. This research was designed in the qualitative research method and the data were evaluated following the qualitative method. The sample group of the research consisted of 80 geography teachers who teach geography at various high schools in Almaty, Kazakhstan. The researchers developed a semi-structured interview form to consult the opinions of teachers about the difficulties encountered in online education. As a result of the research, Geography teachers found measurement and evaluation opportunities in face-to-face education more advantageous than in online education. In line with the findings obtained from the research, it has emerged that it is necessary to make improvements for the healthy application of criterion evaluation technology in online measurement and evaluation.

 

Keywords: Assessment; criterion assessment; evaluation; online learning.
Effects of smartphone utilization on junior high school students’ mathematics performance
Authors: Peteros Emerson , De Vera John V. , Laguna Cristy G. , Lapatha IV Viotelino Christian B. , Mamites Irene O. , Astillero Jeffrey C.
Published: April 2022

Smartphones are widely used among high school students nowadays. With their constant use of this technology, they have become more dependent on it. This study assessed the extent of smartphone utilisation and the academic performance of the 195 junior high school students at a public national high school. Respondents were identified using stratified random sampling and were asked to answer a survey questionnaire assessing their smartphone utilisation during their math classes

while their performance in the subject was determined using their First Quarter grades. The data gathered were treated using descriptive and inferential statistics. The results revealed that the respondents had very satisfactory performance and they often use their smartphones during their math classes. Smartphone utilisation has a negative negligible correlation with the student's academic performance in Mathematics. Furthermore, Smartphone utilisation has no significant relationship between the respondents’ math performance. Hence, teachers are encouraged to monitor students’ use of gadgets during their math classes.

 

Keywords: academic performance, Mathematics, junior high school students, smartphone utilisation
Digital citizenship in education and its implication
Authors: Capuno Reylan , Suson Roberto , Suladay Decem , Arnaiz Vivian , Villarin Imelda , Jungoy Emelyn
Published: April 2022

Nowadays, billions of people across the world communicate with one another using a variety of technological means. As a result of this connection, we now live in a digital world where people can learn, work, play, and socialize with ease. Likewise, educators of all skills levels may not understand how to use technology effectively. Hence, both students and teachers need to become a member of a digital citizenry. Findings revealed that in terms of the elements of digital citizenship, teachers are significantly higher than students. The results indicate that students are at risk in this digital environment along with the covid-19 pandemic.  This critical aspect addresses the schools to provide initiative and integrate digital citizenship in the curriculum in order to provide a responsible digital citizen.

Keywords: Digital citizenship, Basic Education, Digital education, Self-education, Responsible citizen