bluuebunny/crossref_metadata_2025 huggingface dataset:
Modern Methods for Assessing the Technical Condition of Building Engineering Systems
Authors:   Design-Technological Bureau of Concrete and Reinforced Concrete (JSC «KTB RC» (6, str. 15A, 2nd Institutskaya Street, Moscow, 109428, Russian Federation), Davidyuk A.A. , Artemiev E.A. ,   Design-Technological Bureau of Concrete and Reinforced Concrete (JSC «KTB RC» (6, str. 15A, 2nd Institutskaya Street, Moscow, 109428, Russian Federation), Streltsov S.А. ,   Design-Technological Bureau of Concrete and Reinforced Concrete (JSC «KTB RC» (6, str. 15A, 2nd Institutskaya Street, Moscow, 109428, Russian Federation), Voskanyan R.S. ,   Design-Technological Bureau of Concrete and Reinforced Concrete (JSC «KTB RC» (6, str. 15A, 2nd Institutskaya Street, Moscow, 109428, Russian Federation)
Published: December 2020

On the basis of the results of many years work in the inspection of engineering systems of buildings and structures, the presented work reflects aspects of obsolescence or imperfection of the regulatory document of the Russian Federation GOST 31937–2011 «Buildings and structures. Rules for inspection and monitoring of technical condition» in part of section 5.4. The types of work that are not taken into account in the GOST, but are necessary when inspecting for an objective assessment of the technical condition of engineering systems and the possibility of further trouble-free operation are considered. The authors propose modern inspection methods that make it possible, due to the instrumental tools used, to more accurately determine the operational capabilities of systems, identify hidden shortcomings and further develop optimal measures with the maximum improvement of indicators for financial expenses for major repairs of systems as a whole or individual elements.
Protection of Bearing Structures of Buildings Against the Influence of Vibration Generated by Railway Transport
Authors:   esearch Institute of Building Physics of the Russian Academy of Architecture and Construction Sciences (2, Lokomotivny proezd, Moscow, 127238, Russian Federation), Smirnov V.A. ,   National Research Moscow State University of Civil Engineering (26, Yaroslavskoye Shosse, Moscow, 129337, Russian Federation)
Published: December 2020

Currently, the railway network is widely developed, many of which pass through settlements and cities; in some proximity to buildings, including high-rise buildings. The movement of trains on the track causes a certain level of vibrations that are transmitted through the ground to nearby buildings, and cause vibrations of various structures. In this regard, when designing railway tracks or constructing buildings in some proximity to railways, it is necessary to assess the possible vibration impact of rail transport on structures at the design stage and, if necessary, provide measures to protect buildings from negative vibration effects. However, to date, there has not been a standardized method for determining the vibration level at the design stage. The method of predicting the vibration impact of railway transport presented in the article will make it possible to estimate the degree of vibration impact of railway transport on buildings and structures at the design stage, and, if necessary, develop design solutions for vibration isolation that protect buildings and structures from negative vibration effects and create acoustic comfort conditions in the premises.
İSMÂİL DEDE EFENDİ EKOLÜNDE USTA-ÇIRAK (HOCA-ÖĞRENCİ) İLİŞKİLERİ
Authors: ÇIRAK Cem , TUTU Sıtkı Bahadır
Published: December 2020

Geleneksel Türk müziğinin tarih boyunca karşılaştığımız önemli şahsiyetlerinden olan İsmâil Dede Efendi, kalıcı ve başarılı eserler üretmesine ve birçok önemli öğrenci yetiştirmesine bağlı olarak bir “zirve” kabul edilmiştir. Birçok araştırmacı ve musikişinasın klasik dönem olarak benimsediği sürecin son perdesinin Dellalzâde, Mutafzâde, Mehmet Bey ve Zekâî Dede gibi önde gelen isimleri İsmâil Dede’nin eğitiminden geçmiş bestecilerdir. Sanatçılığı kadar hocalık niteliği de yüksek bir besteci olan İsmâil Dede, yetiştirdiği öğrencileriyle birlikte burada İsmâil Dede Ekolü olarak tanımladığımız müzik ekolünü oluşturmuştur. Burada; meşk uygulamasının detayları ekol mensuplarının biyografilerindeki anekdotlardan öğrenilirken, aynı zamanda meşk birlikteliğinin, ortak kültür dairesinde oluşan ortak sanat yönelimlerinin sağladığı zemînin, hocalar ve öğrenciler arasında kurulan ilişkinin yüksek ahlak seviyesine teşvik eden duygusal katmanların keşfedildiği boyutları incelenmiştir. Bu sayede meşk uygulamasının teknik özelliklerinin ötesindeki kişisel ilişkiler ve ileri seviye derslerdeki çalışmalar tespit edilmiştir. İleri seviye derslerde, eser ezberlemenin haricinde bestecilik hakkında yüksek seviye derslere geçilmiş, dersler müzik icrâlarının yapıldığı sosyal etkinliklere evrilerek genişlemiştir. Hoca-öğrenci arasındaki eğitim ve duygu yoğunluğuna bağlı olarak gelişen çok katmanlı manevi ilişkiler de burada incelenmiştir. Bu ilişkiler hem meslekî hem duygusal açılardan hayat boyu sürmüştür. Çalışmanın günümüz müzik eğitiminde verimliliği artırmaya imkân sağlayabileceği düşünülmektedir.
МЕТОДЫ ПОДОБИЯ И ТРЕХМЕРНОЕ МОДЕЛИРОВАНИЕ ЭЛЕКТРИЧЕСКОЙ АКТИВНОСТИ СИНОАТРИАЛЬНОГО УЗЛА СЕРДЦА КРОЛИКА И СОПРЯЖЕННОГО С НИМ МИОКАРДА ПРЕДСЕРДИЯ
Authors:   Медицинский университет «Реавиз», Галанин В.В.
Published: December 2020

Показана возможность применения методов теории подобия для трехмерного моделирования электрической активности cиноатриального узла сердца кролика и сопряженного с ним сократительного миокарда предсердия. Предлагаемая математическая модель представляет собой модель иерархического типа, в которой на верхнем уровне воспроизводится процесс взаимодействия cиноатриального узла и сопряженного с ним сократительного миокарда предсердия; на нижнем уровне модели отражена динамика ионных процессов на мембранах кардиомиоцитов. Приведены примеры использования данной трехмерной модели для описания: а) генерации ритма в cиноатриальном узле сердца; б) явления удвоения периода следования потенциалов действия на участке сократительного миокарда предсердия с пониженной электропроводимостью межклеточных контактов; в) модулирующего влияния электрического взаимодействия фибробластов и кардиомиоцитов на электрическую активность синоатриального узла.
Role of Hippocampal Neurogenesis in Alcohol Withdrawal Seizures
Authors: Basu Sreetama , Suh Hoonkyo
Published: December 2020

Chronic alcohol consumption results in alcohol use disorder (AUD). Interestingly, however, sudden alcohol withdrawal (AW) after chronic alcohol exposure also leads to a devastating series of symptoms, referred to as alcohol withdrawal syndromes. One key feature of AW syndromes is to produce phenotypes that are opposite to AUD. For example, while the brain is characterized by a hypoactive state in the presence of alcohol, AW induces a hyperactive state, which is manifested as seizure expression. In this review, we discuss the idea that hippocampal neurogenesis and neural circuits play a key role in neuroadaptation and establishment of allostatic states in response to alcohol exposure and AW. The intrinsic properties of dentate granule cells (DGCs), and their contribution to the formation of a potent feedback inhibitory loop, endow the dentate gyrus with a “gate” function, which can limit the entry of excessive excitatory signals from the cortex into the hippocampus. We discuss the possibility that alcohol exposure and withdrawal disrupts structural development and circuitry integration of hippocampal newborn neurons, and that this altered neurogenesis impairs the gate function of the hippocampus. Failure of this gate function is expected to alter the ratio of excitatory to inhibitory (E/I) signals in the hippocampus and to induce seizure expression during AW. Recent functional studies have shown that specific activation and inhibition of hippocampal newborn DGCs are both necessary and sufficient for the expression of AW-associated seizures, further supporting the concept that neurogenesis-induced neuroadaptation is a critical target to understand and treat AUD and AW-associated seizures.
Analysis of Risk Factors in Dementia Through Machine Learning
Authors: Balea-Fernandez Francisco Javier , Martinez-Vega Beatriz , Ortega Samuel , Fabelo Himar , Leon Raquel , Callico Gustavo M. , Bibao-Sieyro Cristina
Published: December 2020

Background: Sociodemographic data indicate the progressive increase in life expectancy and the prevalence of Alzheimer’s disease (AD). AD is raised as one of the greatest public health problems. Its etiology is twofold: on the one hand, non-modifiable factors and on the other, modifiable. Objective: This study aims to develop a processing framework based on machine learning (ML) and optimization algorithms to study sociodemographic, clinical, and analytical variables, selecting the best combination among them for an accurate discrimination between controls and subjects with major neurocognitive disorder (MNCD). Methods: This research is based on an observational-analytical design. Two research groups were established: MNCD group (n = 46) and control group (n = 38). ML and optimization algorithms were employed to automatically diagnose MNCD. Results: Twelve out of 37 variables were identified in the validation set as the most relevant for MNCD diagnosis. Sensitivity of 100%and specificity of 71%were achieved using a Random Forest classifier. Conclusion: ML is a potential tool for automatic prediction of MNCD which can be applied to relatively small preclinical and clinical data sets. These results can be interpreted to support the influence of the environment on the development of AD.
Feasibility of training using full immersion virtual reality video game in young stroke survivor: A case report
Authors: Park SuHo , Lee DongGeon , Hong SoungKyun , Cho KiHun , Lee GyuChang
Published: December 2020

BACKGROUND: With the recent developments in science, full-immersion virtual reality devices have been developed, which may have feasibility for stroke rehabilitation. OBJECTIVE: This case report investigated the feasibility of training using a full-immersion virtual reality video game for improving motor function, balance, and gait in a young stroke survivor. METHOD: The case was a 27-year-old woman with stroke. A training using full-immersion virtual reality video game (Sony PlayStation®VR) was performed for 30 minutes per session, 3 sessions per week, for 6 weeks, with a total of 18 sessions. Before training and at each training for 6 weeks, with a total of 19 times, the motor function, balance, and gait were assessed using the Motor Assessment Scale (MAS), Berg Balance Scale (BBS), Timed Up and Go (TUG) Test, and Tinetti Balance Assessment, 10 Meter Walk Test (10MWT), Tinetti Gait Assessment, and Dynamic Gait Index (DGI). RESULTS: During the training, there were no adverse events reported. The case achieved 14 points higher than the pre-assessment with 34 points on the MAS, 16 points higher than the pre-assessment with 48 points on BBS, 6.85 sec lower than the pre-assessment, with 13.58 sec on TUG, 5 points higher than the pre-assessment with 13 points on the Tinetti Balance Assessment, 5.36 sec lower than the pre-assessment, with 8.15 sec on the 10MWT, 4 points higher than the pre-assessment with 10 points on the Tinetti Gait Assessment, and 10 points higher than the pre-assessment with 21 points on the DGI. CONCLUSION: This case report suggests that training using a full-immersion virtual reality video game may be a safe and effective method to improve motor function, balance, and gait in a young stroke survivor.
Provisioning For New Entrepreneurs Using The Canvas Business Model In The Mlaras Village Business Group
Authors: Purwanto Nuri
Published: December 2020

Business canvas model is a model that sends and captures the value of a business consisting of 9 elements contained in the core of a business that is presented simply and easily understandable, the tighter business competition and the covid-19 virus outbreak has brought major changes in the economy and the real impact is on the MSME sector therefore STIE PGRI Dewantara Jombang is moved to conduct a community service program with the theme is training to create a business plan canvas model , simple and easy to apply creation there are three methods used in community service conducted this time, namely, a lecture model that presents about canvas business theory, the second model of baking practice as a form of implementation of value preposition and segmentation and the second is the presentation and discussion model to assess the level of understanding of the participants regarding the material that has been done before, the process of activities goes smoothly without being constrained , as well as the open insights of participants on the importance of making business planning before doing business.
Klasik Arap Şiirinde Yerilen Kötü Bir Ahlak: Mal/Servet Biriktirmek
Authors: Arslan Adnan
Published: December 2020

As in the literature of every nation, the Arabs have preserved their precious words about moral virtues through the record of literature. One of these virtues is to spend a contented life away from ambition. The ambition to stockpile goods and stinginess are among the bad morals that the Quran and hadith prevent. The ambition to save and extravagance has been mentioned as two themes in classical Arabic poetry and many poets in this regard have criticized the exorbitant situation. The first three or even four centuries of the Abbasid period corresponds to the socio-economically prosperous period of the Muslims. Therefore, Arab poets who were brought up in this period of history naturally condemned in their poetry not poverty and poverty, but going to extremes with a life of wealth and luxury. In this study, the poems of the Arab poets of the Classical period, whose traces we have been following for a long time, about this exorbitant / extremism are included. The poems that great poets such as Ibn al-Rûmî, Abu Temmâm, Abu al-Atâhiye and al-Mutanabbî said within the scope of the subject were examined in terms of content. Under the prominent headings, the poems that are frequently mentioned in literary sources were selected and the perspective of the poets to the relevant theme was discussed.
Eksperymentalne badania pilotów dronów telewizyjnych: metody gromadzenia, wizualizacji i analizy danych dotyczących ruchu oka i głowy pilota w czasie lotu z widocznością drona
Authors: Kożdoń-Dębecka Monika , Strzelecki Sebastian
Published: December 2020

Obraz rejestrowany przez drony telewizyjne, włączany do materiałów reporterskich i relacji live, rozszerza możliwości informacyjne współczesnych telewizji. Ponieważ technologia ta wykorzystywana jest w przemyśle telewizyjnym od niedawna, badania dotyczące pilotów telewizyjnych dronów są jeszcze stosunkowo skromne. Kwerenda literatury wskazuje, że naukowcy stale poszukują najbardziej efektywnych metod badań pracy pilotów dronów telewizyjnych, m.in. w celu poprawy parametrów używanych przez tych pilotów kontrolerów lotu dronów. Cel: stworzenie i przetestowanie eksperymentalnej metody badawczej wykorzystującej techniki realizacji obrazu wideo, która, w zestawieniu z innymi metodami stosowanymi w badaniach medioznawczych (eyetracking i badania deklaratywne), pozwoli na uzyskanie komplementarnych danych dotyczących ruchów głowy i oka pilota drona umożliwiających obserwację drona i ekranu kontrolera drona. Metody badań: pomiary biometryczne: eyetracking, eksperymentalna metoda technik realizacji i analizy obrazu wideo, metoda sędziów kompetentnych, badanie ankietowe. Wyniki i wnioski: potwierdzono przydatność przyjętych metod w prowadzeniu badań dotyczących obserwacji drona i jego kontrolera w czasie lotu z widocznością drona. Wartość poznawcza: zastosowanie przyjętej metody eksperymentalnej pozwoliło na wyodrębnienie współczynnika lotu VLOS (lot z widocznością drona), którego wartość może wskazywać na poziom bezpieczeństwa i efektywności ﬁlmowania dronem. W wymiarze praktycznym współczynnik ten może być przydatny m.in. przy projektowaniu szkoleń dla pilotów dronów telewizyjnych oraz w ocenie ryzyka lotu w danej przestrzeni powietrznej.
Media w płynnej pandemii 2020. Komunikacja w czasie lockdownu: oddzielnie, ale razem
Authors: Goban-Klas Tomasz
Published: December 2020

Artykuł dotyczy korzystania z mediów oraz ich funkcji w czasie pandemii koronowirusa. Teza: ogromny wzrost znaczenia komunikacji zmediatyzowanej w sytuacji ﬁzycznego dystansowania się w warunkach pandemii, którą można dookreślić jako „płynną”, gdyż przybierającą cechy Baumanowskiego pojęcia „płynnej nowoczesności”. Graﬁczny obraz koronowirusa i jego potoczna nazwa oraz maseczka na twarzach, pokazywane przez media, są podstawowym składnikiem społecznej konstrukcji obrazu pandemii w skali globalnej. COVID-19 jest przeto konstruktem biologicznym, ale także medialnym i społecznym. Zarządzany przez władze lockdown w pierwszym kwartale pandemii był powszechnie i spolegliwie przestrzegany, co w dużej mierze było pochodną umocnienia „kultury strachu”. Jednocześnie umacniały się formy kontaktów na odległość, a nawet działań grupowych. Metoda badawcza: obserwacja uczestnicząca w zdalnym nauczaniu i pracy zdalnej. Analiza wykorzystania nielicznej literatury tematu, desk research wypowiedzi eksperckich. Wyniki i wnioski: duży chaos informacyjny w pierwszej fazie pandemii. Nasilenie fake newsów w mediach społecznościowych. Podatny grunt dla stygmatyzacji społecznej oraz teorii spiskowych. Wartość poznawcza: ukazanie medialnego wymiaru pandemii oraz jego konsekwencji dla umocnienia pozycji wielkich ﬁrm informacyjno-komunikacyjnych (GAFA) i wzrostu znaczenia form medialnej komunikacji we wszystkich rodzajach kontaktów społecznych. Artykuł wskazuje na wagę analiz funkcji, pozycji i roli mediów – masowych, społecznościowych i indywidualnych – w warunkach przestrzennej separacji. Zawarte w nim rozważania mają ponadto wymiar praktyczny – mogą być adaptowane i rozwijane w praktyce medialnej.
Ramy prawne działalności sprawozdawców sądowych w świetle orzecznictwa Europejskiego Trybunału Praw Człowieka w Strasburgu
Authors: Kakareko Ksenia , Sobczak Jacek
Published: December 2020

Celem pracy jest przedstawienie przez pryzmat orzeczeń Europejskiego Trybunału Praw Człowieka najważniejszych problemów, jakie pojawiły się w ostatnich latach na tle dziennikarskich sprawozdań z przebiegu rozpraw sądowych. Metody badań: w zakresie analizy tekstów normatywnych i wywodów Europejskiego Trybunału Praw Człowieka wykorzystano całą paletę metod prawniczych, wśród nich metodę egzegezy tekstu prawnego i prawniczego według wskazań koncepcji derywacyjnej, czemu towarzyszyła analiza lingwistyczna, w ujęciu zarówno topiczno-retorycznym, jak i proceduralnym. Konieczne było odniesienie się do hermeneutyki prawniczej jako metody wyjaśniania tekstu. Wykorzystano także metodę leksykalną oraz, w mniejszym stopniu, metodę porównawczą, pozwalającą na przedstawienie głębokich aksjologicznych źródeł systemu prawnego. Pomocną okazała się również analiza instytucjonalno-prawna. Wyniki i wnioski: przeprowadzone badania dowodzą, że obowiązki, jakie spoczywają na dziennikarzach pełniących funkcję sprawozdawców sądowych, są niezwykle poważne, a z ich istnienia oraz uwarunkowań, w jakich one funkcjonują, świat dziennikarski – jak się wydaje – nie do końca zdaje sobie sprawę. Odnosi się to w szczególności do publikacji fotografii i wizerunków zarówno oskarżonych, jak i innych osób, których dotyczy postępowanie sądowe, ponadto do publikacji dokumentów, zdjęć z akt sprawy, a także kwestii nagrań. Wartość poznawcza: przedstawione judykaty powinny uświadomić osobom pełniącym funkcję sprawozdawców z przebiegu procesów oraz tym, którzy dopiero podejmują się tej roli, jakim wyzwaniom przyjdzie im sprostać w trakcie wykonywania tej pracy.
浅谈煤矿掘进支护技术在复杂地质条件下的应用
Authors: 马 栋
Published: December 2020

在社会快速发展的带动下，使得我国社会经济水平得到了显著的提升，从而有效的推动了各个领域的发展壮大，为科学技术的发展带来了诸多的机遇，在这种形势下，大量的新型科学技术被人们研发出来，并被切实的引用到了实践之中取得了良好的成效。在煤矿生产行业中，煤矿开采工作的环境相对较为复杂，并且煤矿资源开采过程中极易遇到诸多外界不良因素的影响，从而会对煤矿生产工作的安全性造成诸多的威胁。煤矿生产企业在实施资源开采工作的时候，往往都需要使用到支护技术，通常在相对较为复杂的环境中，都需要建造大量的巷道，其目的就是为煤炭资源的运输和开采工作提供更多的便利，所以针对复杂环境下煤矿掘进支护技术展开全面深入的研究分析是具有较强的现实意义的。就当下实际情况来说，我国掘进支护工作所采用的技术都是巷道支护技术，在这项技术刚刚被研发出来的时候，所使用的支护材料都是木料，随着社会的发展逐渐的演变成为了钢材料，最后转变成为了当前的锚杆支护。文章主要围绕煤矿掘进支护技术在复杂地质条件中的使用展开全面深入的研究分析，希望能够对我国煤矿生产行业的良好发展有所帮助。
房屋建筑工程施工阶段工程造价的控制与管理
Authors: 钟 政诺
Published: December 2020

近年来，我国逐渐的加大了经济对外开放的力度，从而有效的推动了社会经济水平的不断提升，这样就为各个领域的发展壮大带来了良好的机遇，切实的加快了房屋建筑工程领域的发展。工程造价其实质就是指在实际组织实施建筑工程项目施工工作的过程中，涉及到的各项成本和资金的花费的总和，诸如：人工费用、材料费用、机械租赁费用等等。工程造价在建筑工程项目中最为主要的作用就是评价、调控、预测。高水平的工程造价管理工作，可以针对建筑工程项目施工各项工作进行合理的管控，促使工程整体成本得到有效的控制，提升各项资金的利用效率。
口袋公园生态化景观设计策略研究
Authors: 王 振威
Published: December 2020

现阶段，我国在进行园林绿化工程建设过程中应始终融入节能理念，构建起环境友好型社会，园林绿化工程施工时应降低对生态环境的影响，获得最大的生态效应。在这样的发展环境下，我国在进行生态化建设过程中取得了较好的成果，因此在城市不断建设与发展过程中应不断加强生态化建设力度。口袋公园的建设面积相对较小，所以在进行设计时也具有一定的局限性，口袋公园也得到了更好的发展与优化，在城市生态建设中起到了一定的作用同时也得到各城市的认可。因此，各城市在建设口袋公园时应对设计进行完善，从而提高城市生态化建设质量。
建筑工程管理的重要性和创新方法
Authors: 李 振国
Published: December 2020

近年来，我国加大了经济改革开放的力度，从而推动了国内各个领域的发展壮大，尤其是建筑工程行业发展势头更加的迅猛。在建筑工程行业中，建筑工程管理工作不但能够对建筑工程施工质量造成一定的影响，并且还与建筑工程企业未来发展密切相关，所以需要我们务必要加以重点关注。在开展建筑工程建设工作的时候，必须要深入研究建筑企业在管理工程上的模式，然后结合企业发展的具体状况，创新建筑工程的管理理念和方法。与此同时也需要加大力度针对建筑工程实施全面的监督工作，促进建筑管理工作效率和质量的不断提高，并且在控制工程整体施工成本方面也具有重要的影响作用。特别是在如今经济和科技飞速发展的背景下，建筑工程仍是一项比较复杂的工程，所以为了能够彻底的解决上述问题，建筑施工单位务必要从各个细节入手，全面的落实建筑工程管理工作，充分结合各方面实际情况和需要来对管理方法加以优化和创新。
软土地区基坑开挖变形性状分析
Authors: 文 少磊
Published: December 2020

随着科技的不断发展，软土地区的基坑开挖得到的关注越来越多。软土地区的强度相对较低且含水量较大，所以在基坑开挖过程中容易产生变形问题。文章通过对软土地区的基坑开挖进行分析，并结合实际对软土地区基坑开挖变形性状提出个人观点，希望为关注软土地区基坑开挖的人群带来参考。
试论房屋建筑土建工程中混凝土施工技术分析
Authors: 邵 锋 , 程 杰
Published: December 2020

近年来，在多方面利好因素的带动下，使得我国综合国力得到了显著的提升，从而为各个领域的发展壮大带来了良好的机遇，尤其是建筑工程行业的发展势头十分的迅猛。在建筑工程施工建造中，混凝土是其中较为关键的一项施工材料，其最为突出的特性就是耐久性和抗压性，将其与钢筋结构进行混合使用能够有效的提升建筑工程结构的稳定性和抗震性。正是因为上述有优越性的存在，所以混凝土广泛的收到了人们的青睐，并被大范围的运用到了建筑工程施工工作之中，在建筑工程中起到了至关重要的作用。鉴于此，这篇文章主要针对房屋建筑土建工程中混凝土施工技术展开全面深入的研究分析，希望能够对我国建筑工程行业的良好发展起到积极的推动作用。
影响建筑材料试验检测质量主要因素及其控制
Authors: 王 鑫
Published: December 2020

近年来，我国社会经济水平得到了显著的提升，从而为城市化建设工作的全面开展创造了良好的基础，在这种发展形势下，使得民众的思想意识发生了巨大的变化，人们对生活环境提出了更高的要求，推动了我国建筑工程行业的持续发展。经过实践调查分析我们最终总结出，建筑工程施工材料质量与工程施工质量存在直接的关联，所以要想从根本上对建筑工程施工质量加以保证，那么最为关键的就是需要对建筑工程施工材料质量加以根本保障。合理的运用建筑材料试验检测工作能够准确的判断建筑工程施工材料质量情况，但是因为在实施施工材料试验检测工作的过程中，往往会遇到诸多因素的影响影响，所以会对检测结果准确性造成一定的损害。鉴于此，这篇文章主要针对建筑材料试验检测质量影响因素展开全面深入的研究分析，希望能够对我国建筑工程行业的稳步健康发展有所帮助。
机电一体化系统在机械工程中的应用研究
Authors: 李 晨
Published: December 2020

在社会快速发展的带动下，各个领域都得到了显著的发展壮大。在将老旧模式的机械工程加以实践运用的过程中，不但需要投入大量的精力，并且也会受到外界诸多条件的限制，工作效率和质量都无法得到有效的提升，这样对于其他相关行业的发展也会形成诸多的限制。机电一体化系统属于一种控制系统，其中涉及到大量的前沿科学技术，将其与机械工程相融合，从而能够形成独立的机械系统学科。就现如今实际情况来说，将机电一体化系统运用到机械工程之中，不但可以有效的提升工作的效率和质量，还能够切实的避免人力资源发生浪费的问题，促进整个行业的持续、稳定发展，为我国社会经济的快速发展创造了良好的基础。
工程建设管理中存在的问题以及应对策略研究
Authors: 任 耀
Published: December 2020

现代社会不断发展，我国各个行业也在市场经济发展背景下得到进一步改进成长，尤其是建设工程项目，近些年的发展有目共睹。作为建设工程项目中非常重要的工作内容，工程管理占据着非常重要的位置，其能够对建设项目的各个环节进行协调指挥，发挥其指导作用，能够有效衔接各个工序和岗位，能够保证安全顺利地完成工程项目建设。当前工程建设管理中仍然存在一些不同程度的问题，为此，应当加强建设管理优化，提升建设管理水平，从而确保工程整体建设效果。
岩土工程勘察设计与施工中地质问题研究
Authors: 江 树铭
Published: December 2020

我国国土面积辽阔，所以导致各个地区的地质结构情况以及环境情况都存在明显的差异，在各个地区进行建筑工程施工工作之前务必要安排专业人员针对地区情况实施工程地质勘察工作，结合勘察结果来制定完善的工程施工方案。在实际开展岩土工程设计和施工工作的过程中，往往会受到多方面因素造成的影响，从而会导致施工工作无法有序高效的开展，并且也会对工程施工质量的提升形成诸多的制约。所以，要想针对上述问题加以合理的解决，那么就需要对岩土工程水文地质勘察工作的落实加以重点关注，加大力度针对水文地质问题进行深入研究分析，综合各方面实际情况和需要，利用有效的方式方法来对水文地质中所存在的各种问题进行合理的解决，从根本上确保建筑工程施工质量不断提升。
上软下硬及全断面硬岩地层盾构刀具磨损规律及性能分析
Authors: 李 兆国 , 魏 子青 , 鱼 志鸿
Published: December 2020

文章中立足于广东深圳某地铁项目盾构隧道工程，通过刀具磨损量测定，刀具更换频率等数据的统计，对复合土压平衡盾构在全~强、中~微风化花岗岩构成的上软下硬、软硬不均、全断面硬岩等地层中不同形式的盘型滚刀的磨损规律及不同品牌刀具性能、寿命等进行分析研究，总结出一些在该类地层中盾构施工刀具选配的一些思路和参考依据。
高层建筑钢筋混凝土结构设计问题分析
Authors: 孔 鹏飞
Published: December 2020

随着我国城市化进程的不断加快，土地资源的紧缺，高层建筑的设计在满足安全性和正常使用方向功能的前提下，也开始更加注重城市空间的利用、建筑风格的变化和使用功能的多样性，从而使得建筑结构体型越来越复杂，其中结构体系的选择，抗侧力构件的布置，局部不规则处、关键受力构件的布置与选择就显得尤为重要。这就需要我们将结构受力体系与建筑使用功能的要求进行有效的结合与考虑，制定针对性的解决处理措施。作为结构设计师，就必须在建筑方案设计时就对整个建筑结构可能存在的问题有一个合理的预估，走好工程项目的第一步。
钢筋混凝土屋面防水技术
Authors: 张 汐
Published: December 2020

房屋经过长时间风吹雨打后会产生渗漏等问题的发生，轻则对人们的日常生活造成影响，重则可能会导致生命财产受到损失。当房屋发生渗漏问题时，房屋维修是一项十分复杂的工作，同时也需要大量的维修费用，如果不及时处理房屋渗漏问题，则有可能造成安群事故。做好屋面结构防水渗透问题，是房屋建筑中的重要一部分，它对于房屋使用寿命和安全问题有着不可忽视的作用。对屋面结构的防水进行深入研究，可以有效降低财产经济损失与安全事故的发生。文章经过搜集大量相关资料与文献，结合自身工作经验，对屋面防水技术的未来发展进行探讨，并对当前屋面防水问题提出相关建议，以供参考。
ADHERENCE TO PROPHYLAXIS IN RELATION TO QUALITY OF LIFE AND ANXIETY LEVEL IN TURKISH PATIENTS WITH SEVERE HAEMOPHILIA A
Authors: KAYA Zühre , KİRKİZ Serap , ALBAYRAK Meryem , GÜNEY Esra , AYTAC Selin , ÖZBEK Namık Yaşar
Published: December 2020

Background: Bleeding increases anxiety and reduces quality of life (QoL) for patients with severe haemophilia A. This study investigated adherence to prophylaxis in relation to QoL and anxiety level in haemophilia A patients.
Methods: Forty-three patients with severe haemophilia A were stratified into three groups by age: 12 children aged 2-13 years, 17 adolescents aged 14-21 years, and 14 adults aged 21-65 years. Quality of life and anxiety level were assessed using the 36-item Short Form Health Survey (SF-36) and the State-Trait Anxiety Inventory (STAI), respectively. Regular prophylaxis (RP) and pharmacokinetic (PK)-guided prophylaxis were prescribed for 30 and 13 patients, respectively.
Results: All the children (n=12; nine RP, three PK-guided prophylaxis) and 10 (58.8%, PK-guided prophylaxis) of the adolescents were completely adherent to prophylaxis. Seven (41.2%) of the adolescents and all 14 adults (100%) were non-adherent to prophylaxis. Compared to findings for the adolescents, anxiety level was higher among the children’s parents and among the adults (p<0.05 for both). The QoL level was lower for the adults than for the parents of children and for the adolescents (p<0.05 for both).
Conclusion: Pharmacokinetic-guided prophylaxis for adults and home treatment for children in haemophilia A would enhance adherence to prophylaxis, increase QoL and reduce anxiety levels.
The Effect of Communication and Job Satisfaction Towards the Performance of Civil Servants in Jambi Province, Indonesia
Authors: Fauzan Muhammad Oceano , Disman Disman , Yuniarsih Tjutju , Santoso Budi
Published: December 2020

This research examines the effect of communication and job satisfaction on the performance of civil servants in Jambi Province in order to provide adequate input and knowledge for readers. Data were obtained by distributing questionnaires to employees with a Likert' scale of 1 – 2, used for analysis. The results showed that communication (X1) has no partial effect on performance (Y), while job satisfaction (X2) has a positive and significant effect on performance (Y). Similarly, there is a partial effect between communication (X1) and job satisfaction (X2) variables towards the performance (Y) on the Manpower and Transmigration Office employees in Jambi Province.
The Readiness of Disadvantaged Regions in Implementing E-Government in Indonesia: Case Study in East Seram Regency
Authors: Arey Hasri , Suripto Suripto , Hapsari Rian D. , Akbar Muhammad Firyal
Published: December 2020

The East Seram Regency is a disadvantaged region in Indonesia with many sub-districts that do not have access to internet and electricity. The remaining options for sub-districts was hindered because it is limited by wilderness and free oceans and the APBD (Regional Revenue and Expenditure Budget) in this regency is also limited. Although, the implementation of e-Government by the Regent are willing to follow the mandate of Presidential Regulation No. 95 of 2018 concerning Electronic-Based Government Systems (SPBE). The purpose of this study was to analyze and determine the readiness of the East Seram Regency in implementing the e-government system in Indonesia. This study used a mixture of qualitative and quantitative methods and data collection technique was also carried out by using a questionnaire for 76 respondents, in-depth interviews for 7 informants, and documentation. The result showed the quality of public human resources and civil servants in the field of communication and the informatics are low. Also, the ICT infrastructure such as internet, servers, networks, and computer equipment are inadequate. The East Seram Regency is a disadvantaged region that prioritizes physical development infrastructure rather than allocating a high budget for the information technology tools. Therefore, it is concluded that the East Seram Regency as one of the disadvantaged region in Indonesia whose Local Government is 'Not Ready' to implement an e-government system as mandated by Presidential Regulation No. 95 of 2018.
Village Development Planning in The Digital Era: The Role and Interest of Stakeholders in Kotaagung, Tanggamus Regency
Authors: Yulianto Yulianto , Meilinda Selvi Diana , Puspawati Ani Agus , Utami Anisa
Published: December 2020

This study aims to describe the planning process of village development in the digital era, focusing on the dynamics of stakeholder roles and interests. From descriptive qualitative research methods, village development planning in the digital era flows under the Ministry of Home Affairs Regulation No. 114/2014 and Law No. 6 of 2014. Furthermore, the dynamics of the planning process are more flexible with the role of media and technology sophistication. In the digital era, the village development planning process, especially in Kotaagung Sub-district villages, Tanggamus Regency, Lampung, is swift, which cuts bureaucracy and stagnated planning stages. Moreover, invitations to the village deliberations are conveyed in writing, a process that only fulfills administrative matters for archiving. Massive invitations are delivered through the devices of stakeholders deemed essential to be presented to determine development priorities. The dynamics of stakeholder and media are seen from the movement and correlation of roles, interests, and influences. That shows stakeholders are the main subject in village development planning in today's digital era. Therefore, the Village needs to respond to the changing times by planning and implementing the system with digitization in a systematic and applicable manner.

Keywords: Development Planning; Village Development; Development Digitization
On the Use of Phenolic Compounds Present in Citrus Fruits and Grapes as Natural Antioxidants for Thermo-Compressed Bio-Based High-Density Polyethylene Films
Authors: Rojas-Lema Sandra , Torres-Giner Sergio , Quiles-Carrillo Luis , Gomez-Caturla Jaume , Garcia-Garcia Daniel , Balart Rafael
Published: December 2020

This study originally explores the use of naringin (NAR), gallic acid (GA), caffeic acid (CA), and quercetin (QUER) as natural antioxidants for bio-based high-density polyethylene (bio-HDPE). These phenolic compounds are present in various citrus fruits and grapes and can remain in their leaves, peels, pulp, and seeds as by-products or wastes after juice processing. Each natural additive was first melt-mixed at 0.8 parts per hundred resin (phr) of bio-HDPE by extrusion and the resultant pellets were shaped into films by thermo-compression. Although all the phenolic compounds colored the bio-HDPE films, their contact transparency was still preserved. The chemical analyses confirmed the successful inclusion of the phenolic compounds in bio-HDPE, though their interaction with the green polyolefin matrix was low. The mechanical performance of the bio-HDPE films was nearly unaffected by the natural compounds, presenting in all cases a ductile behavior. Interestingly, the phenolic compounds successfully increased the thermo-oxidative stability of bio-HDPE, yielding GA and QUER the highest performance. In particular, using these phenolic compounds, the onset oxidation temperature (OOT) value was improved by 43 and 41.5 °C, respectively. Similarly, the oxidation induction time (OIT) value, determined in isothermal conditions at 210 °C, increased from 4.5 min to approximately 109 and 138 min. Furthermore, the onset degradation temperature in air of bio-HDPE, measured for the 5% of mass loss (T5%), was improved by up to 21 °C after the addition of NAR. Moreover, the GA- and CA-containing bio-HDPE films showed a high antioxidant activity in alcoholic solution due to their favored release capacity, which opens up novel opportunities in active food packaging. The improved antioxidant performance of these phenolic compounds was ascribed to the multiple presence of hydroxyl groups and aromatic heterocyclic rings that provide these molecules with the features to permit the delocalization and the scavenging of free radicals. Therefore, the here-tested phenolic compounds, in particular QUER, can represent a sustainable and cost-effective alternative of synthetic antioxidants in polymer and biopolymer formulations, for which safety and environmental issues have been raised over time.
Comparison of Circulating Tumour DNA and Extracellular Vesicle DNA by Low-Pass Whole-Genome Sequencing Reveals Molecular Drivers of Disease in a Breast Cancer Patient
Authors: Ruhen Olivia , Mirzai Bob , Clark Michael E. , Nguyen Bella , Salomon Carlos , Erber Wendy , Meehan Katie
Published: December 2020

There is increasing recognition of circulating tumour DNA (ctDNA) as a non-invasive alternative to tumour tissue for the molecular characterisation and monitoring of disease. Recent evidence suggests that cancer-associated changes can also be detected in the DNA contained within extracellular vesicles (EVs). As yet, there has been limited investigation into the relationship between EV DNA and ctDNA, and no studies have examined the EV DNA of breast cancer patients. The aim of this study was to use low-pass whole-genome sequencing to identify copy number variants (CNVs) in serial samples of both ctDNA and EV DNA from a patient with breast cancer. Of the 52 CNVs identified in tumour DNA, 36 (69%) were detected in at least one ctDNA sample and 13 (25%) in at least one EV DNA sample. The number of detectable variants in ctDNA and EV DNA increased over the natural history of the patient’s disease, which was associated with progression to cerebral metastases. This case study demonstrates that, while CNVs are detectable in patient EV DNA, ctDNA has greater sensitivity than EV DNA for serial monitoring of breast cancer.
Reaction Mechanism for Methane-to-Methanol in Cu-SSZ-13: First-Principles Study of the Z2[Cu2O] and Z2[Cu2OH] Motifs
Authors: Engedahl Unni , Arvidsson Adam A. , Grönbeck Henrik , Hellman Anders
Published: December 2020

As transportation continues to increase world-wide, there is a need for more efficient utilization of fossil fuel. One possibility is direct conversion of the solution gas bi-product CH4 into an energy-rich, easily usable liquid fuel such as CH3OH. However, new catalytic materials to facilitate the methane-to-methanol reaction are needed. Using density functional calculations, the partial oxidation of methane is investigated over the small-pore copper-exchanged zeolite SSZ-13. The reaction pathway is identified and the energy landscape elucidated over the proposed motifs Z2[Cu2O] and Z2[Cu2OH]. It is shown that the Z2[Cu2O] motif has an exergonic reaction path, provided water is added as a solvent for the desorption step. However, a micro-kinetic model shows that neither Z2[Cu2O] nor Z2[Cu2OH] has any notable activity under the reaction conditions. These findings highlight the importance of the detailed structure of the active site and that the most stable motif is not necessarily the most active.
The Relative Merits of an Individualized Versus a Generic Approach to Rating Functional Performance in Childhood Dystonia
Authors: Gimeno Hortensia , Farber Jessica , Thornton Jessica , Polatajko Helene
Published: December 2020

Aims. The Performance Quality Rating Scale (PQRS) is an observational measure that captures performance at the level of activity and participation. Developed for use with the Cognitive Orientation to daily Occupational Performance (CO-OP), it is a highly individualized approach to measurement. CO-OP is currently being studied in childhood-onset hyperkinetic movement disorders (HMD) and deep brain stimulation. The purpose of this study was to compare two different approaches to rating performance, generic (PQRS-G) and individualized (PQRS-I), for children with childhood-onset hyperkinetic movement disorders (HMD) including dystonia. Method. Videotaped activity performances, pre and post intervention were independently scored by two blind raters using PQRS-G PQRS-I. Results were examined to determine if the measures identified differences in e performance on goals chosen by the participants and on change scores after intervention. Dependent t-tests were used to compare performance and change scores. Results. The two approaches to rating both have moderate correlations (all data: 0.764; baseline: 0.677; post-intervention: 0.725) and yielded some different results in capturing performance. There was a significant difference in scores at pre-intervention between the two approaches to rating, even though post-intervention score mean difference was not significantly different. The PQRS-I had a wider score range, capturing wider performance differences, and greater change between baseline and post-intervention performances for children and young people with dystonic movement. Conclusions. Best practice in rehabilitation requires the use of outcome measures that optimally captures performance and performance change for children and young people with dystonic movement. When working with clients with severe motor-performance deficits, PQRS-I appears to be the better approach to capturing performance and performance changes.
Comparative Computational Study of L-Amino Acids as Green Corrosion Inhibitors for Mild Steel
Authors: Kasprzhitskii Anton , Lazorenko Georgy , Nazdracheva Tatiana , Yavna Victor
Published: December 2020

This research evaluates the inhibitory effect of L-amino acids (AAs) with different side chain lengths on Fe (100) surfaces implementing Monte Carlo (MC) simulation. A quantitative and qualitative description of the adsorption behavior of AAs on the iron surface has been carried out. Calculations have shown that the absolute values of the adsorption energy of L-amino acids increase with side chain prolongation; they are also determined by the presence of heteroatoms. The maximum absolute value of the adsorption energy AAs on the iron surface in accordance with the side chain classification increases in the following sequence: Glu (acidic) < Gln (polar) < Trp (nonpolar) < Arg (basic). AAs from nonpolar and basic groups have the best adsorption ability to the iron surface, which indicates their highest inhibitory efficiency according to the results of the MC simulation. The calculation results agree with the experimental data.
Comparison of Microwave Short Time and Oven Heating Pretreatment on Crystallization of Raisins
Authors: Alvarez Lorena , Urrutia Paulina , Olivares Araceli , Flores Agustín , Bhandari Bhesh , Almonacid Sergio
Published: December 2020

Crystalline material can develop on the surface of raisins during storage and transport, affecting the final acceptability of the product. In this work, a mild thermal pretreatment was applied to raisins to melt the pre-existing crystals and the effect of such thermal treatments on the development of crystals over a storage period was investigated. The raisins selected for this study were of the Thompson seedless variety from one Chilean company. The thermal pretreatment of raisins at 50 °C and 70 °C for 20 min in an oven and microwave (800 W) irradiation for 15 s resulted in a reduction in the percentage of crystallized raisins (w/w) from more than 50% in the control samples to less than 10% after 35 days of storage at 15 and 25 °C in a 57% relative humidity environment. The results showed that some textural parameters, such as cohesiveness and chewiness, were not affected by thermal treatment and were independent of storage temperature.
Novel Polymorphisms and Genetic Features of the Prion Protein Gene (PRNP) in Cats, Hosts of Feline Spongiform Encephalopathy
Authors: Kim Hyeon-Ho , Kim Yong-Chan , Kim Kiwon , Kim An-Dang , Jeong Byung-Hoon
Published: December 2020

Prion diseases are fatal neurodegenerative disorders characterized by vacuolation and gliosis in the brain. Prion diseases have been reported in several mammals, and genetic polymorphisms of the prion protein gene (PRNP) play an essential role in the vulnerability of prion diseases. However, to date, investigations of PRNP polymorphisms are rare in cats, which are the major host of feline spongiform encephalopathy (FSE). Thus, we investigated the genetic polymorphisms of the cat PRNP gene and analyzed the structural characteristics of the PrP of cats compared to those of dog, prion disease-resistant animal. To investigate the genetic variations of the cat PRNP gene in 208 cats, we performed amplicon sequencing and examined the genotype, allele and haplotype frequencies of cat PRNP polymorphisms. We evaluated the influence of cat PRNP polymorphisms using PolyPhen-2, PANTHER, PROVEAN and AMYCO. In addition, we carried out structural analysis of cat PrP according to the allele of nonsynonymous single nucleotide polymorphism (SNP) (c.457G > A, Glu153Lys) using Swiss-PdbViewer. Finally, we compared the structural differences between cat and canine PrPs for SNPs associated with prion disease resistance in dogs. We identified a total of 15 polymorphisms, including 14 novel SNPs and one insertion/deletion polymorphism (InDel). Among them, Glu153Lys was predicted to affect the structural stability and amyloid propensity of cat PrP. In addition, asparagine at codon 166 of cat PrP was predicted to have longer hydrogen bond than aspartic acid at codon 163 of canine PrP. Furthermore, substitution to dog-specific amino acids in cat PrP showed an increase in structural stability. To the best of our knowledge, this is the first study regarding the structural characteristics of cat PRNP gene.
Causal Relationship between Adiponectin and Diabetic Retinopathy: A Mendelian Randomization Study in an Asian Population
Authors: Huang Yu-Chuen , Chang Ya-Wen , Cheng Chun-Wen , Wu Chia-Ming , Liao Wen-Ling , Tsai Fuu-Jen
Published: December 2020

Adiponectin (APN) is suggested to be a potential biomarker for predicting diabetic retinopathy (DR) risk, but the association between APN and DR has been inconsistent in observational studies. We used a Mendelian randomization (MR) analysis to evaluate if circulating APN levels result in DR. We applied three different genetic risk scores (GRS): GRSAll combined all 47 single nucleotide polymorphisms (SNPs), which from a genome-wide association study (GWAS) database-catalog reach significance level; GRSLimited comprised 16 GRSAll-SNPs with a rigorous threshold (p < 5.0 × 10−8 for GWAS), and GRSAPN combined 5 SNPs significantly associated with APN level. The MR-inverse-variance weighted method analysis showed that for each 1-SD increase in genetically induced increase in plasma APN, the OR of having DR was β = 0.20 (95% CI: −0.46–0.85, p = 0.553) for GRSAPN, 0.61 (95% CI: 0.10–1.13, p = 0.020) for GRSAll, and 0.57 (95% CI: −0.06 to 1.20, p = 0.078) for GRSLimited. Sensitivity analysis, including MR-egger regression and the weighted-median approach, did not provide evidence of the pleiotropic effect of IVs. Limited evidence for the causal role of APN in DR risk among Taiwanese diabetic patients was shown based on MR analysis in the present study.
Phenylketonuria Diagnosis by Massive Parallel Sequencing and Genotype-Phenotype Association in Brazilian Patients
Authors: Tresbach Rafael Hencke , Sperb-Ludwig Fernanda , Ligabue-Braun Rodrigo , Tonon Tássia , de Oliveira Cardoso Maria Teresinha , Heredia Romina Soledad , da Silva Rosa Maria Teresa Alves , Martins Bárbara Cátia , Poubel Monique Oliveira , da Silva Luiz Carlos Santana , Maillot François , Schwartz Ida Vanessa Doederlein
Published: December 2020

Phenylketonuria (PKU) is a common inborn error of amino acid metabolism in which the enzyme phenylalanine hydroxylase, which converts phenylalanine to tyrosine, is functionally impaired due to pathogenic variants in the PAH gene. Thirty-four Brazilian patients with a biochemical diagnosis of PKU, from 33 unrelated families, were analyzed through next-generation sequencing in the Ion Torrent PGM™ platform. Phenotype–genotype correlations were made based on the BioPKU database. Three patients required additional Sanger sequencing analyses. Twenty-six different pathogenic variants were identified. The most frequent variants were c.1315+1G>A (n = 8/66), c.473G>A (n = 6/66), and c.1162G>A (n = 6/66). One novel variant, c.524C>G (p.Pro175Arg), was found in one allele and was predicted as likely pathogenic by the American College of Medical Genetics and Genomics (ACMG) criteria. The molecular modeling of p.Pro175Arg indicated that this substitution can affect monomers binding in the PAH tetramer, which could lead to a change in the stability and activity of this enzyme. Next-generation sequencing was a fast and effective method for diagnosing PKU and is useful for patient phenotype prediction and genetic counseling.
Selection of Reference Genes for Normalization of Gene Expression in Thermobia domestica (Insecta: Zygentoma: Lepismatidae)
Authors: Bai Yu , Lv Ya-Nan , Zeng Mei , Jia Pei-Yao , Lu Hu-Na , Zhu Yi-Bo , Li Sheng , Cui Ying-Ying , Luan Yun-Xia
Published: December 2020

Zygentoma occupies a key evolutionary position for understanding the evolution of insect metamorphosis but has received little attention in terms of genetic analysis. To develop functional genomic studies in this insect, we evaluated five candidate internal reference genes for quantitative RT-PCR (qPCR) studies from Thermobia domestica, a representative species of Zygentoma, including Actin 5C (Actin5C), Elongation factor-1 alpha (EF1A), Ribosome protein S26 (RPS26), Ribosome protein L32 (RPL32), and Superoxide dismutase 2 (SOD2), at different developmental stages, in various body parts, and under dsRNA microinjection and starvation stresses, using four algorithms (delta Ct, geNorm, NormFinder and BestKeeper) and a comparative algorithm (RefFinder). Specific suitable reference genes were recommended across specific experimental conditions, and the combination of RPS26 and RPL32 was appropriate for all tested samples. Employing our selected reference gene combination, we investigated the gene expression pattern of Myoglianin (Myo), a crucial gene-regulating insect metamorphosis, in ametabolous T. domestica, and demonstrated the efficiency of RNA interference (RNAi) in firebrat nymphs. This study provides a basis for reliable quantitative studies of genes and greatly benefits evolutionary and functional genomics studies in Zygentoma.
Results of Mentoring in the Psychosocial Well-Being of Young Immigrants and Refugees in Spain
Authors: Sánchez-Aragón Anna , Belzunegui-Eraso Angel , Prieto-Flores Òscar
Published: December 2020

This study examined the change processes associated with the Nightingale project, a community-based mentoring programme whose aim is to promote the social inclusion of minors of immigrant origin. A pre-test–post-test study was conducted on a group of 158 young immigrants between the ages of 8 and 15, in which the influence of the mentoring programme on the youths’ psychosocial well-being was measured. Non-parametric tests were used to calculate the results before and after mentoring, comparing the results over a six-month period and controlling for sex and age. The analyses reflected associations between mentoring and improvements in specific aspects of the emotional well-being of young immigrants and highlighted the potential of mentorships to cushion the stressful events they are subjected to in the process of adapting to a new social reality.