bluuebunny/crossref_metadata_2025 huggingface dataset:
Atenção ao pré-natal de gestantes de risco e fatores associados no Município de São Paulo, Brasil
Authors: Sanine Patricia Rodrigues , Venancio Sonia Isoyama , Silva Fernanda Luz Gonzaga da , Aratani Nathan , Moita Maria Lucia Garcia , Tanaka Oswaldo Yoshimi
Published: October 2019

Resumo: Avaliou-se a atenção ao pré-natal de gestantes de alto risco e a identificação de fatores associados, no Município de São Paulo, Brasil. Pesquisa avaliativa com 689 gestantes encaminhadas pela atenção primária à saúde (APS) para a atenção especializada (AE) em 2016. Considerou-se o modelo de APS como variável independente principal: unidade de saúde da família (USF), unidade básica de saúde (UBS) e UBS mista. Utilizou-se modelos de regressão logística múltipla (forward selection) para os desfechos “início precoce do pré-natal” e “acompanhamento compartilhado entre AE e APS”. Evidenciou-se maior chance de “início precoce do pré-natal” e “acompanhamento compartilhado entre AE e APS” ser encaminhada por USF. Independentemente da APS, apresentou associação para “início precoce do pré-natal” ter a pele branca, e para “acompanhamento compartilhado entre AE e APS” ter recebido visita domiciliar. Os resultados evidenciam a importância de serviços organizados segundo o modelo USF, que realizam visita domiciliar e são atentos às vulnerabilidades implícitas nas características individuais das gestantes.
Análise espaço-temporal do efeito da poluição do ar na saúde de crianças
Authors: Matos Emerson Pedreira , Reisen Valdério Anselmo , Serpa Faradiba Sarquis , Prezotti Filho Paulo Roberto , Leite Maria de Fátima Silva
Published: October 2019

O objetivo foi investigar a associação de curto prazo entre a poluição do ar e atendimentos em emergências por doenças respiratórias, em crianças de 0 a 6 anos. Estudo ecológico, espacial e temporal realizado na Região Metropolitana da Grande Vitoria, Espírito Santo, Brasil. Utilizou-se o modelo aditivo generalizado (MAG) de regressão de Poisson, com a variável dependente o número diário de atendimentos por doenças respiratórias, e as variáveis independentes, concentrações diárias dos poluentes atmosféricos (MP10, SO2, NO2, O3 e CO), temperatura, umidade e precipitação pluviométrica. Por meio das médias diárias das concentrações, foram feitas estimativas para toda a região e análises in loco com a consideração de crianças residentes no entorno de 2km de oito estações de monitoramento da qualidade do ar. O incremento de 10μg/m3 nos níveis de concentração dos poluentes atmosféricos aumentou o risco de atendimento em emergência por doença respiratória. Na região geral, para o MP10, o aumento foi de 2,43%, 2,73% e 3,29% nos acumulados de 5, 6 e 7 dias, respectivamente. Para o SO2, o acréscimo foi de 4,47% no dia da exposição, 5,26% dois dias após, 6,47%, 8,8%, 8,76% e 7,09% nos acumulados de 2, 3, 4 e 5 dias, respectivamente. O CO apresentou associação significativa para residentes no entorno de duas estações, e o O3 somente em uma. Mesmo dentro dos limites estabelecidos pela Organização Mundial da Saúde, os poluentes MP10, SO2, NO2 e O3 estão associados ao maior risco para atendimento por doenças respiratórias em crianças de 0 a 6 anos, e alguns efeitos só foram identificados nas localidades desagregadas por região, isto é, in loco, o que possibilita captar maior variabilidade dos dados.
Facebook recruitment of smokers: comparing gain- and loss-framed ads for the purposes of an Internet-based smoking cessation intervention
Authors: Machado Nathália Munck , Gomide Henrique Pinto , Bernardino Heder Soares , Ronzani Telmo Mota
Published: October 2019

Abstract: Gain- and loss-framed messages about smoking behavior have commonly been used to promote cessation. However, there are still no clear conclusions as to what kind of message is more effective for motivating smokers to quit. This study compared the effectiveness of loss- and gain-framed messages in the online recruitment of smokers via Facebook Advertising. Loss- and gain-framed messages about smoking were created and released as Facebook ads. Users who clicked on the ads were automatically redirected to the “Live Without Tobacco” intervention (http://www.vivasemtabaco.com.br). The amount spent on the ads was BRL 647.64. Data were collected from the Facebook Ads platform and from a relational database. Analyses were performed on the 6,350 users who clicked on one of the ads and 1,731 who were successfully redirected to the intervention. Gain-framed ads reached 174,029 people and loss-framed ads reached 180,527. The former received 2,688 clicks, while the latter received 3,662. The cost of the click was BRL 0.12 per gain-framed ad and BRL 0.09 per loss-framed ad. Loss-framed ads reached more users, got more clicks (and website accesses), and led to more accounts and quit plans being created. Loss-framed messages about smoking appear to be more cost-effective for both initial recruitment and intervention engagement. Facebook has proven to be a good outreach and recruitment tool and can be a solution for the difficulty in reaching smokers for cessation interventions.
Avaliação das informações do Sistema de Informações sobre Nascidos Vivos (SINASC), Brasil
Authors: Szwarcwald Célia Landmann , Leal Maria do Carmo , Esteves-Pereira Ana Paula , Almeida Wanessa da Silva de , Frias Paulo Germano de , Damacena Giseli Nogueira , Souza Júnior Paulo Roberto Borges de , Rocha Narayani Martins , Mullachery Priscila Melissa Honorato
Published: October 2019

Resumo: Neste trabalho, avaliam-se quantitativa e qualitativamente as informações do Sistema de Informações sobre Nascidos Vivos (SINASC). A cobertura das informações por município foi estimada pela razão entre nascidos vivos informados e estimados. Para avaliação da qualidade das informações do SINASC, relacionou-se o sistema à base de dados do estudo Nascer no Brasil, 2011-2012, e foram estimados coeficientes kappa de concordância. Em 2013, a cobertura das informações foi alta e homogênea em todas as Unidades da Federação. Entretanto, a análise por município brasileiro apresentou maior heterogeneidade espacial. Quanto à qualidade de preenchimento das informações do SINASC, os coeficientes kappa de concordância foram estatisticamente diferentes de zero para todas as variáveis testadas (p < 0,001), e as distribuições marginais para todas as variáveis consideradas foram semelhantes nas duas bases de dados. A idade gestacional foi a variável que mostrou pior concordância, com valor de kappa de 0,461. O indicador que descreve as inconsistências, medido pela soma do quadrado das diferenças entre os percentuais de prematuridade informados e esperados por faixa de peso ao nascer, teve o valor mais alto na Região Norte e o menor na Região Sul, apontando para desigualdades geográficas na mensuração da idade gestacional.
Acesso ao exame citológico do colo do útero em região de saúde: mulheres invisíveis e corpos vulneráveis
Authors: Fernandes Noêmia Fernanda Santos , Galvão Jôse Ribas , Assis Marluce Maria Araújo , Almeida Patty Fidelis de , Santos Adriano Maia dos
Published: October 2019

Este artigo avalia o acesso ao exame Papanicolaou na Estratégia Saúde da Família (ESF), em municípios de uma região de saúde. O controle do câncer do colo do útero depende de uma ESF organizada, portanto, avaliar o acesso ao teste de Papanicolaou revela a qualidade da assistência neste nível de atenção. Trata-se de estudo qualitativo, com dados produzidos em 10 grupos focais, perfazendo 70 participantes, em quatro municípios. Analisaram-se as dimensões organizacional, simbólica e técnica do acesso ao exame preventivo, tendo como condição marcadora o câncer do colo do útero. Os resultados indicaram que residir em zona rural era barreira para o acesso ao exame Papanicolaou e reforçavam as iniquidades. Enfermeiros eram a principal referência para a realização do exame preventivo. A ausência de itens necessários à coleta de material citopatológico foi uma barreira de acesso em todos os municípios. Havia entraves de acesso às mulheres com alguma deficiência e às mulheres lésbicas, com atendimento fragmentado e descontextualizado das singularidades pessoais. Os inúmeros entraves de acesso ao Papanicolaou expuseram a seletividade da ESF na região de saúde, visto que reproduzia a invisibilidade das mulheres com maior vulnerabilidade social e acentuava as desigualdades.
Análise do impacto orçamentário da viscossuplementação no tratamento não cirúrgico da osteoartrite de joelho
Authors: Silva Grasiela Martins da , Senna Katia Marie Simões e , Sousa Eduardo Branco de , Tura Bernardo Rangel
Published: October 2019

Resumo: A osteoartrite de joelho afeta cerca de 3,8% da população mundial e se manifesta por dor, edema, rigidez e redução da função articular, impactando na qualidade de vida do paciente. O tratamento consiste na modalidade farmacológica, não farmacológica e cirúrgica. A viscossuplementação (ácido hialurônico intra-articular) se propõe a oferecer alívio dos sintomas e a possibilidade de adiamento da cirurgia. Este estudo estimou o impacto orçamentário entre a associação desse medicamento e o tratamento não cirúrgico (tratamento padrão), sob a perspectiva do Sistema Único de Saúde. Com base no pressuposto de que 5% dos portadores da doença seguem para tratamento e nos custos diretos das modalidades: farmacológica e não farmacológica foram calculados os cenários de referência e alternativos que compararam as diferentes opções de tratamento para um horizonte temporal de três anos. A análise principal estimou um impacto orçamentário incremental de aproximadamente R$ 126 milhões (1 ampola anual) e R$ 252 milhões (2 ampolas anuais). Já a diacereína, um condroprotetor oral, avaliada como uma opção alternativa, mostrou um impacto de R$ 334 milhões no orçamento em relação ao tratamento padrão, o que proporciona um aumento de 24% no custo em relação ao uso de 2 ampolas anuais de ácido hialurônico, tornando-a economicamente menos vantajosa. A viscossuplementação pode proporcionar maior qualidade de vida ao paciente, redução de custos para o sistema e otimização do fluxo de atendimento nas unidades de saúde. As estimativas apresentadas neste estudo podem auxiliar o gestor quanto à melhor utilização dos recursos financeiros e consequente tomada de decisão quanto à incorporação da tecnologia.
Azithromycin and Full-Mouth Scaling For the Treatment of Generalized Stage III and IV Periodontitis: A 6-Month Randomized Comparative Clinical Trial
Authors: Oliveira Alcione M. S. D. , Costa Fernando O. , Nogueira Letícia Mara R. , Cortelli Sheila C. , Oliveira Peterson A. D , Aquino Davi R. , Miranda Taís B. , Cortelli José R.
Published: October 2019

Abstract The effectiveness of azithromycin combined with full-mouth scaling procedures was compared to quadrant-wise scaling combined with the same dosage of azithromycin when treating periodontitis patients over a 6-month period. In this randomized clinical trial study, thirty-four individuals diagnosed with generalized stage III and IV periodontitis underwent baseline, 3-month, and 6-month post-treatment examinations. The study population was randomly assigned to either full-mouth scaling (FMS) or quadrant-wise scaling and root planning (QSRP) in addition to their taking of systemic azithromycin (500 mg/day) for three consecutive days. Periodontal probing depth (PD), clinical attachment level (CAL), gingival index (GI), and plaque index (PI) were monitored along with the quantification of total bacterial load and red complex bacterial species (Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola) in subgingival samples by real time polymerase chain reaction. The volume of gingival crevicular fluid (GCF) was also monitored over time. The primary outcomes included improvements of PD and CAL. Data was statistically analyzed through a repeated-measures analysis of variance (ANOVA) test, multiple least significant difference (LSD) comparisons, Kruskal-Wallis, Friedman, and paired Student t-tests (p<0.05). FMS and QSRP provided similar PD, CAL, GI, PI, and GCF improvements. After treatment, the FMS group displayed lower mean values of total bacterial load and red complex bacterial species in comparison to the QSRP group. FMS and QSRP in conjunction with systemic azithromycin appeared to be an effective and reliable short-term therapeutic approach for the treatment of generalized stage III and IV periodontitis. However, FMD demonstrated superiority in regard to the 6-month antibacterial effects when compared to QSRP.
Differential Molecular Signature of Human Saliva Using ATR-FTIR Spectroscopy for Chronic Kidney Disease Diagnosis
Authors: Rodrigues Renata PCB , Aguiar Emilia MG , Cardoso-Sousa Leia , Caixeta Douglas C , Guedes Cizilene CFV , Siqueira Walter L , Maia Yara C Paiva , Cardoso Sergio V , Sabino-Silva Robinson
Published: October 2019

Abstract The symptoms of chronic kidney disease (CKD) are often not specific or absent in the early stages of this illness. Therefore, there is a demand for developing low cost, non-invasive and highly accurate platforms for CKD diagnostics. We hypothesized that the level of specifics salivary components changes when CKD is emplace, which could be clinically used to discriminate CKD patients from healthy subjects. The present study aimed to compare salivary components between CKD patients and matched control subjects by using attenuated total reflection-Fourier Transform Infrared (ATR-FTIR) spectroscopy. The predictive power of salivary components was evaluated by receiver operating characteristic (ROC) curves. Several components were identified, and 4 of them showed different expression (p<0.05) between CKD and control subjects. Thiocyanate (SCN-, 2052 cm-1) and phospholipids/carbohydrates (924 cm-1) vibrational modes using original and second-derivative spectra by ATR-FTIR could potentially be used as salivary biomarkers to differentiate CKD than control subjects. The combination of original and second-derivative spectra by ATR-FTIR of 924 cm-1 vibrational modes could reach 92.8% sensitivity and 85.7% specificity for CKD detection. Despite, the limitation of our investigation, the acquired data indicates that salivary vibrational modes by ATR-FTIR platform should be further explored as an auxiliary diagnostic tool for CKD.
Analysis of Molecular Changes Induced By Mineral Trioxide Aggregate On sPLA2
Authors: Lopes Murilo B , Soares Veronica C.G , Fagundes Fabio H.R , Gonini-Junior Alcides , Kaneshima Renan H , Guiraldo Ricardo D , Diz-Filho Eduardo B.S. , Berger Sandrine B , Felizardo Klissia R , Santos Marcelo L. dos
Published: October 2019

Abstract The aim of this study was to analyze the effects of MTA on the structure and enzymatic activity of sPLA2 in order to provide subsidies for improvement in the formulation of the product. MTA powder was incubated for 60 min in the presence of sPLA2 and was analyzed by chromatography, electrospray mass (ESI-MS) and small-angle X-ray scattering (SAXS). It was find that the elution profile, retention time, and fragmentation of sPLA2 were altered after treatment with MTA. Calcium was the MTA component that most amplified the inflammatory signal. Significant interactions were found between MTA and sPLA2, which could aid in our understanding of the mechanisms of action of MTA during the inflammatory process and it may facilitate the structural modification of MTA, thereby improving its biological safety and consequently the rate of the treatment success.
Reinforced Glass-ceramics: Parametric Inspection of Three-Dimensional Wear and Volumetric Loss after Chewing Simulation
Authors: Tribst João Paulo Mendes , Alves Larissa Marcia Marques , Piva Amanda Maria de Oliveira Dal , Melo Renata Marques de , Borges Alexandre Luiz Souto , Paes-Junior Tarcísio José Arruda , Bottino Marco Antonio
Published: October 2019

Abstract The aim of this study was to investigate the three-dimensional wear, volumetric loss and surface roughness after chewing simulation of two glass ceramics. Lithium disilicate (LD, Emax CAD, Ivoclar) and Zirconia reinforced lithium silicate (ZLS, Vita Suprinity, Vita Zhanfabrick) discs (n=20/g) were scanned to obtain stereolithography (STL) files for each sample. All discs were submitted to chewing simulation with sliding configuration (30 N, 300,000 cycles, 6 mm and 1.7 Hz) with steatite as antagonist. The samples were then scanned again and the volume loss and the deepest defect depth was measured using the superimposed file from the baseline using three-dimensional digital parametric inspection software (GOM Inspect, Braunschweig, Germany). Surface roughness (Ra and Rz) was analyzed with a contact profilometer. Data were analyzed by one-way ANOVA and Tukey test (α=0.5%). ANOVA showed significant differences among the groups. Considering the ceramic volume loss, wear depth defect length and Rz roughness, LD (-22.09±5.57%; 0.80±0.06 µm; 3.08±1.02 µm) showed higher mean values than ZLS (-15.67±4.51%; 0.56±0.09 µm; 1.51±0.90 µm). Ra mean values were similar for both materials (p=0.064). All discs exhibited slight surface scratches along with the sliding direction with pitted wear patterns, while large cracks were observed on wear traces. These same areas can be identified in blue, overlapping the STL files before and after chewing simulation in inspection software. The linear reduction generated by sliding contact shows a graph with a similar wear pattern shape. ZLS was more resistant to wear than LD, with less volume loss and shallower surface defects.
Interfacial Properties and Bottom/Top Hardness Ratio Produced by Bulk Fill Composites in Dentin Cavities
Authors: Chaves Letícia Virgínia de Freitas , Oliveira Samila Neres de , Özcan Mutlu , Acchar Wilson , Caldas Marília Regalado Galvão Rabelo , Assunção Isauremi Vieira de , Souza Rodrigo Othávio de Assunção e , Borges Boniek Castillo Dutra
Published: October 2019

Abstract The aim of this study was to evaluate the bond strength, bottom/top hardness ratio, marginal adaptation, and interfacial nanoleakage of regular viscosity bulk fill composites (RVBFC) and regular viscosity traditional composites (RVTC). Two RVBFC (Filtek Bulk Fill and Aura Bulk Fill) and two RVTC (Filtek Z250XT and Aura) were assessed. Forty conical cavities (4.8×2.8×4.0) were prepared in bovine dentin and restored with composites (n=10). After 24h in water, marginal adaptation was evaluated by staining with a caries detector. The top and bottom surfaces of the conical restorations were stained for five seconds and the gap percentage in the composite/dentin interface was determined using digital images on a measurement program (ImageTool). The Vickers microhardness was measured and the bottom/top microhardness ratio (B/T) was determined. Push-out bond strength test was performed in a universal testing machine (0.5mm/min) and failure modes were evaluated in a stereomicroscope (20×). Other specimens (n=3) were produced for interfacial nanoleakage evaluation. Data were analyzed using one and two-way ANOVA and Tukey’s test (α=0.05). The gap percentage was higher in the bottom compared to the top. The B/T ratio of the Aura Bulk Fill was statistically lower than other composites. Push-out bond strength were similar among composites. The RVBFC presented lower nanoleakage than the RVTC in the bottom of the conical restoration and there was no difference among the materials in the top surfaces. In conclusion, Filtek Bulk Fill performed better than Aura Bulk Fill regarding the analyzed properties.
Preemptive Use of Piroxicam on Tooth Sensitivity Caused By In-Office Bleaching: A Randomized Clinical Trial
Authors: Peixoto Aline de Carvalho , Vaez Savil Costa , Soares Karla DaniellyAlves , Ferreira Lorena Fernandes , Loguercio Alessandro Dourado , Faria-e-Silva André Luis
Published: October 2019

Abstract This clinical trial evaluated the effect of preemptive use of the non-steroidal anti-inflammatory drug piroxicam in a single dose 30 min prior to in-office bleaching on the prevention of tooth sensitivity (TS) reported by patients. Fifty patients were submitted to two sessions of in-office tooth bleaching with 35% hydrogen peroxide used for 2 sessions, each consisting of a single 45-min application, with an interval of 7 days between session. Thirty minutes prior to the procedure, the patient randomly received a single dose of piroxicam (200 mg) or placebo in a double-blind, randomized, crossover design. The TS was evaluated using verbal rate (VRS) and visual analog (VAS) scales during the bleaching procedure and at 24 h after each session. The color changes were assessed by the Vita Bleachedguide scale 1 week after each bleaching session. Risk of TS was calculated from the VRS and analyzed by the McNemar test, while the level of TS was analyzed by the Mann-Whitney test. For the VAS, t-tests were used to compare data from the treatments at each assessment time. Data regarding color changes were subjected to Wilcoxon and Mann-Whitney tests (α=0.05). The preemptive administration of piroxicam did not affect the risk and level of TS compared to placebo, irrespective of the assessment time. The treatment sequence did not affect bleaching effectiveness. In conclusion, the administration of a single dose of piroxicam prior to in-office tooth bleaching was unable to significantly reduce the risk and level of TS.
Systemic Effects (Risks) of Water Fluoridation
Authors: Cury Jaime A , Ricomini-Filho Antonio P , Berti Francine L. Perecin , Tabchoury Cinthia PM
Published: October 2019

Abstract Since the 1950s, the benefits and risks of fluoridated water use have been debated worldwide. In the past, it was considered that the systemically ingested fluoride would exert its primary preventive effect after being incorporated into the enamel as fluorapatite, making the enamel more resistant to the caries process; however, it is now recognized that the main effect of water fluoridation is local and post eruptive. On the other hand, irrespective of the caries decline reported worldwide, the anticaries benefit of water fluoridation continues to be observed even in developed countries. Regarding the risks, water fluoridation is considered an acceptable community-based method for fluoride delivery, because the risk of developing dental fluorosis lesions due to the ingestion of fluoride during the enamel formation period has been deemed acceptable when contrasted to the anticaries benefits of fluoride. However, the use of fluoride in water to control caries has created a controversy due to data associating water fluoridation as the cause of some systemic diseases. Therefore, the aim of this descriptive review was to discuss the systemic effects (risks) of water fluoridation use.
Singular e universal em Alain Badiou e a hipótese da cientificidade da psicanálise
Authors: Carvalho Wanderley Magno de , França Neto Oswaldo
Published: October 2019

Resumo Este trabalho apresenta a hipótese da cientificidade da psicanálise a partir de uma reflexão sobre as concepções de singular e de universal do filósofo contemporâneo Alain Badiou. Sem pretensão de esgotar tais conceitos e, antes, propondo uma abertura ao debate, faremos apontamentos em duas direções. Na primeira, apresentaremos o conceito de singular e o fragmento de um caso clínico ilustrativo. Nesse âmbito, refletiremos sobre as “orientações no pensamento” propostas pelo filósofo e sobre os possíveis lugares de Freud e da psicanálise nesta categorização. Na direção do conceito de universal, apresentaremos as teses de Badiou e o modo como o filósofo evita a ontoteologia presente, por exemplo, nas ciências modernas. Finalizaremos com uma proposta de como a psicanálise apropria-se dos conceitos de singular e de universal para se diferenciar das outras ciências.
Estilos de cuidado materno em primatas: considerações a partir de uma espécie do Novo Mundo
Authors: Verderane Michele P. , Izar Patrícia
Published: October 2019

Resumo Quando buscamos entender o comportamento humano, comparações com primatas não humanos são especialmente relevantes para identificar homoplasias (características semelhantes que evoluem independentemente em diferentes espécies). Neste artigo, apresentamos um estudo longitudinal de dois anos sobre o comportamento materno de macacos-prego (Sapajus spp.) em condições naturalísticas. Nossos resultados permitiram identificar estilos de cuidado distintos dentro de um contínuo de permissividade a proteção. O desenvolvimento observado do vínculo entre mães e filhotes sugere que o período de dependência de filhotes de macaco-prego envolve, além de processos de maturação física, o estabelecimento e desenvolvimento de processos psicológicos associados ao sistema de apego. É possível que a variabilidade de estilos maternos resultante da combinação de características de mães, filhotes e contextos socioecológicos, aliada ao prolongamento do vínculo de apego, pavimente caminhos para diferentes trajetórias de desenvolvimento. Como em humanos, esse pode ser um dos mecanismos pelos quais surgem e se consolidam as diferenças interindividuais nas populações adultas.
Culture medium and inoculation methodology for the study of soft root rot caused by Phytopythium sp.
Authors: Silva Jonny Lucio de Sousa , Ishida Alessandra Keiko Nakasone , Cunha Roberto Lisboa , Lima Aline Medeiros , Moura Elisa Ferreira
Published: October 2019

ABSTRACT: Cassava (Manihot esculenta Crantz) is an important crop in Brazil and Pará is the major producer of roots. High temperature and humidity of tropical regions favor the development of various diseases, among them the cassava root rot. The objective of this study was to evaluate the effect of luminosity and culture medium on the mycelial growth and sporulation of Phytopythium sp. associated with different methods of inoculation on cassava roots. In vitro tests for pathogen growth were established in a 2 x 6 factorial design (luminosity x culture medium) with five replicates and the means were compared by t test (P≤0.05). The culture medium containing sweet cassava root produced greater mycelial development and higher pathogen sporulation and it was the most suitable medium for pathogen culture. The culture under absence of light generated better mycelial growth than culture under 12 hour of light. Regarding the type of inoculation, the response was better when deeper injuries were induced.
Reproductive performance of Nellore heifers raised in extensive system undergoing different vaccination protocols in fixed-time artificial insemination (FTAI)
Authors: Schillings Neto Ernest , Nogueira Eriklis , Jardim Rodrigo , Abreu Urbano Gomes Pinto de , Sterza Fabiana Andrade de Melo , Pellegrin Aiesca Oliveira , Juliano Raquel Soares
Published: October 2019

ABSTRACT: This study evaluated the reproductive performance of Nellore heifers without previous vaccination undergoing fixed-time artificial insemination (FTAI) and subsequent natural breeding under different vaccination protocols against infectious bovine herpesvirus 1 (BHV-1), bovine viral diarrhea virus (BVDV), and bovine leptospirosis (BL). A total of 763 animals were included; the group assignment was as follows: T1, control without vaccination; T2, vaccination against BL; T3, vaccination against BHV-1and BVDV; T4,vaccination against combination of BL + BHV-1and BVDV. Vaccination was started 30 days before FTAI (D-40), and a booster dose was administered at D-10. Serological tests were used to verify the occurrence rate of natural infection by BL, BHV-1, and BVDV. Initial pregnancy was diagnosed at D30, D60, and D120 after FTAI. Final pregnancy rates were evaluated by group, weight, body-condition score, occurrence of estrus, inseminator, bull, and occurrence of abortions or embryonic death. In all groups, results indicated seropositivity of 100% for leptospirosis, 77.0-94.0% for BHV-1, and 64.0-87.0% for BVDV. The vaccination protocol was not a significant influencing factor of pregnancy rate and embryonic or fetal mortality; whereas, animal weight at the beginning of the breeding season and presence of estrus at FTAI were significant influencing factors of pregnancy rate. The vaccination protocol had no interference with the reproductive performance of the experimental groups.
Sensory and chemical evaluation of tea brews prepared with the assistance of ultrasound
Authors: Kowalski Radosław , Wyrostek Jakub , Kałwa Klaudia , Kowalska Grażyna , Pankiewicz Urszula , Sujka Monika , Włodarczyk-Stasiak Marzena , Mazurek Artur
Published: October 2019

ABSTRACT: The aim of the study was to evaluate sensory and phytochemical (polyphenols, flavonoids and caffeine) estimation of black and green tea brews obtained in an alternative way through brewing with the assistance of ultrasound. Brews produced with the application of sonication for 2 minutes and 1 minute were the most preferred by the sensory evaluation team. Evaluation of the brews in terms of component descriptors, i.e. fragrance, flavour and colour, was varied and depended on the kinds of tea and on the applied experimental factors. It was demonstrated that ultrasound have a significant effect on the extraction of active substances, i.e. polyphenols, flavonoids and caffeine, from black and green tea. The application of sonication caused a significant increase in the concentration of flavonoids (by ca. 29% and 73%), polyphenols (by ca. 34% and 41%) and caffeine (by ca. 51% and 60%) in the tea brews.
Tracheal avulsion in a cat
Authors: Prestes Rafaela da Silveira , Santos Flaviani Emilia dos , Souza Izabela Patrício de , Marcelino Sóstenes Apolo Correia , Torres Renato Cesar Sacchetto , Malm Christina , Freitas Patrícia Maria Coletto , Beier Suzane Lilian , Ecco Roselene , Nepomuceno Anelise Carvalho
Published: October 2019

ABSTRACT: Tracheal avulsion is a condition seen in small animals and occurs as a result of a traumatic incident to the cervical and/or thoracic regions. The aim of this study is to report a case of tracheal avulsion in a cat using imaging examinations for diagnostic investigation. In this report, we examined an eight-month-old male, cat of undefined breed, diagnosed with tracheal avulsion using complementary imaging tests. This diagnosis was confirmed with post-mortem examination. Radiographic examination of the patient’s thorax and a tracheoscopy were performed. These examinations revealed complete discontinuity of the tracheal circumference, the presence of focal and circumscribed dilation of the tracheal lumen and stenosis. The patient quickly died without clinical and surgical intervention. Macroscopic analysis revealed a tracheal diverticulum confirming the findings of the imaging tests. The use of radiographic examinations in conjunction with tracheoscopy was effective at diagnosing this condition.
Cattle influence on the population structure of yerba mate (Ilex paraguariensis) in Araucaria Forest
Authors: Stedille Lilian Iara Bet , Pires Edicléa Zulian , Gomes Juliano Pereira , Costa Newton Clóvis Freitas da , Bernardi Alison Paulo , Mantovani Adelar
Published: October 2019

ABSTRACT: This study characterized the demography and spatial pattern of a yerba mate (Ilex paraguariensis A.St.-Hil) population covering areas with different use histories (Presence and Absence of Cattle) in a Araucaria Forest. Data collection was performed in three ha, half in each area. The frequency of individuals by height, spatial distribution pattern, diameter distribution (for reproductive individuals) and sexual ratio were evaluated. An inverted “J” pattern predominated, being exclusive to an area with Cattle Presence, a place which presented a lower density of individuals. The predominant spatial distribution pattern was aggregated, and the reproductive individuals have a preferentially random pattern at the shortest distances. Results indicated that cattle presence changes the density of I. paraguariensis individuals and the proportion of individuals in the evaluated demographic classes.
Hematological, biochemical, and blood gas alterations of goat whole blood stored in CPDA-1 and CPD/SAG-M plastic bags
Authors: Tavares Marcondes Dias , Barros Isabella de Oliveira , Sousa Rejane dos Santos , Firmino Paulo Ricardo , Gameleira Jucelio da Silva , Oliveira Francisco Leonardo Costa de , Minervino Antonio Humberto Hamad , Ortolani Enrico Lippi , Alves Barrêto-Júnior Raimundo
Published: October 2019

ABSTRACT: The aim of this study was to evaluate the hematological, biochemical, and blood gas alterations of goat whole blood stored in different blood bags. Seven male, adult, crossbreed goats were used, weighing 62±1.8 kg. Nine hundred milliliters of whole blood from each animal was collected and stored in blood bags (450 ml in each), CPDA-1 (citrate phosphate dextrose-adenine) and CPD/SAG-M (citrate phosphate dextrose with saline-glucose-mannitol) as additive solutions, and kept refrigerated (2-4 ºC) for 42 days. Blood samples were collected from the plastic bags at baseline (T0) and after seven, 14, 21,28, 35, and 42 days for hematological, biochemical, blood gas, and microbiological evaluations. Free hemoglobin, degree of hemolysis, lactate, and pO2were increased in both bags, whereas hydrogen potential (pH) and the total hemoglobin concentration decreased overtime(P<0.05). The red blood cell count, glucose, sodium, and potassium remained stable, compared to the baseline. The CPD/SAG-M bag presented a lower red cell count, globular volume, total hemoglobin, and sodium, and a higher degree of hemolysis and plasma hemoglobin, compared with the CPDA-1 bag. The whole goat blood remained viable for therapeutic use; although, there were some important changes in the variables of the 42-day stored blood in relation to fresh blood (T0). We concluded that the CPDA-1 bag is more suitable for use in the storage of goat blood because of its lower commercial value.
Optimization in timetabling in schools using a mathematical model, local search and Iterated Local Search procedures
Authors: Andrade Pedro Rochavetz de Lara , Steiner Maria Teresinha Arns , Góes Anderson Roges Teixeira
Published: October 2019

Abstract This paper addresses the school timetabling problem, which consists of defining the date and time in which classes will be given by teachers in educational institutions. For this purpose, a tool that uses Operational Research (OR) techniques was developed, focused on generating and optimizing Elementary and High School timetables, taking into account teachers’ preferences for certain days or for sequenced (twinned) classes. Conductive to solving the problem, a Non Linear Binary Integer Programming mathematical model (NLBIP) and Local Search (LS) and Iterated Local Search (ILS) procedures were comparatively applied. A real problem with 14 timetables of public schools in the city of Araucária (in Paraná State, Brazil) was analyzed. The results indicate that the computational time required by the mathematical model is feasible for the problems in question. The ILS technique has the potential for testing larger scale problems, as it presents a dispersion of 3.5% to 7.7% relative to the optimal solution (obtained by the NLBIP) and a computational time that is 15 to 338 times faster.
REVIEW OF TOTAL KNEE ARTHROPLASTY AND THE BRAZILIAN UNIFIED HEALTH SYSTEM: A NATIONAL PROBLEM
Authors: Melo Lucas da Ponte , Losso Guilherme Augusto , Costa Guilherme Henrique Ricardo da , Pécora José Ricardo , Demange Marco Kawamura , Helito Camilo Partezani
Published: October 2019

ABSTRACT Objectives: To analyze, through DATASUS data, the historical trend of revision of total knee arthroplasty (TKA) in the period between 2008-2016 and to relate them to demographic, regional and national aspects. Methods: Elaboration of a historical series between the period 2008-2016, using the database of DATASUS, in the area of Health Information (TABNET). In order to calculate the incidence, the total number of TKA revisions and as denominator the total national, regional or state population for the period studied was used as numerator. Results: The national rate of procedures per 100,000 inhabitants varied between 0.41 and 0.48 in the analyzed period (mean of 0.44). The Southeast region, with 69% of the SBCJ accredited services and 61% of the SBCJ members, was responsible for 60% of the absolute number of procedures performed in Brazil. Conclusions: In absolute numbers, the Southeast region has the highest volume of procedures. However, the highest rate is found in the South region. The North, Northeast and Central-West regions presented unsatisfactory results, well below the others. Level of evidence IV, Economic and decision analysis - development of economic model or decision.
PLATELET-RICH PLASMA (PRP) AND TRANEXAMIC ACID (TXA) APPLIED IN TOTAL KNEE ARTHROPLASTY
Authors: Guerreiro João Paulo Fernandes , Lima Diogenes Rodrigues , Bordignon Glaucia , Danieli Marcus Vinicius , Queiroz Alexandre Oliveira , Cataneo Daniele Cristina
Published: October 2019

ABSTRACT Objective: To evaluate the efficacy of platelet-rich plasma (PRP) and tranexamic acid (TXA) applied in total knee arthroplasty. Methods: We selected and randomized 84 patients. TXA was applied in 23 patients, PRP in 20, and PRP in combination with TXA in 20. Hemoglobin was measured preoperatively and 24 and 48 hours postoperatively. The function questionnaire, pain scale and gain of knee flexion were monitored until the second postoperative year. Results: There was a difference (p <0.01) in the decrease in hemoglobin 48 hours after surgery between the TXA group and the control and PRP groups. In terms of pain, the TXA group at 24 and 48 hours after surgery and the PRP group at 48 hours after surgery showed advantages (p <0.01). Knee flexion gain in the first 24 hours postoperatively was better in the TXA group (p <0.05). Conclusion: TXA was effective in lowering the drop in hemoglobin level, reducing pain and improving movement gain 48 hours after the procedure. PRP was not effective in reducing bleeding or improving knee function after arthroplasty, but provided better control of postoperative pain. Level of Evidence I, Randomized, blinded, prospective clinical trial.
CHRONIC MONTEGGIA FRACTURE-DISLOCATION IN CHILDREN SURGICAL STRATEGY AND RESULTS
Authors: Soni Jamil Faissal , Valenza Weverley Rubele , Matsunaga Carolina Umeta , Costa Anna Carolina Pavelec , Faria Fernando Ferraz
Published: October 2019

ABSTRACT Objective: To report surgical techniques and results in the treatment of chronic Monteggia fracture-dislocation in children. Methods: Six pediatric patients who had undergone a procedure involving the following 6 crucial surgical steps were retrospectively evaluated: 1- extended lateral approach, 2- fibrotic removal, 3-proximal ulnar osteotomy, 4- reduction of the radial head and transcapitellar temporary fixation, 5- ulnar fixation with a straight plate shaped according to the deformity generated by temporary fixation, and 6- transcapitellar Kirschner wire removal. Results: Four patients were women, and four showed the right-sided compromise. The mean age of patients was 8 years, and the minimum follow-up period was 12 months. The mean time from the onset of fracture to treatment was 6 months. Six patients underwent complete flexo/extension, and one patient had a complete prono-supination. In four patients, we observed loss of pronation (by 10° in two, 15° in one, and 20° in one), and one patient had a 15° decrease in supination. We did not observe any redislocation of the radial head in the follow-up evaluation. No complications were observed; the only complaint was salience of the ulnar plate. Conclusions: Our results demonstrated an effective option for the treatment of chronic Monteggia fracture-dislocation in children, even with a small study sample, following the presented technical and surgical strategies. Level of evidence IV, Therapeutic Studies.
QUALITY OF LIFE OF PATIENTS WITH SARCOMA AFTER CONSERVATIVE SURGERY OR AMPUTATION OF LIMBS
Authors: Silva Rogério Santos , Guilhem Dirce Bellezi , Batista Katia Torres , Tabet Lívia Penna
Published: October 2019

ABSTRACT Objective: To conduct an integrative review on quality of life (QOL) of patients with sarcoma who underwent conservative surgery or limb amputation. Methods: We conducted a six-step integrative review by searching the databases LILACS, SciELO, PePSIC, Embase, and PubMed, using the descriptors: “Quality of life”, “Bone cancer”, “Sarcoma”, “Limb Salvage,” and “Amputation.” Ten studies were selected according to: database, type of study, methods, researcher's profession, sex, histological type, title, country/region, and periodical/year of publication. Results: Nine quantitative and one qualitative studies were included. All were conducted by physicians and correlated to QOL with the impact of diagnosis, psychosocial aspects, cancer treatment, and survival. Other aspects included type of surgery, functionality, rehabilitation, and a multidisciplinary approach. The QOL results were similar for conservative surgery and amputation in eight studies. In two, it was concluded that patients undergoing conservative surgery had a better QOL. Conclusion: The number of studies on QOL in patients with sarcoma is small. In most, there was no difference between the study groups. In addition, the studies indicated the importance of evaluation of QOL, since it has a direct effect on patients' physical manifestations and impacts their coping abilities. Level of evidence III, System review.
A RETROSPECTIVE CASE-SERIES ON THE USE OF S53P4 BIOACTIVE GLASS FOR THE ADJUNCTIVE TREATMENT OF SEPTIC DIAPHYSEAL NON-UNION
Authors: Gaiarsa Guilherme Pelosini , Reis Paulo Roberto dos , Kojima Kodi Edson , Silva Jorge Santos , Lima Ana Lucia Lei Munhoz
Published: October 2019

ABSTRACT Objective: Non-union and persistence of infection at a fracture site for long periods are always described as a challenge to orthopedists, especially in cases of severe compound fractures with comminution and segmental bone loss. This is a case series of septic non-unions, using S53P4 bioactive glass for adjunctive treatment, using internal syntheses or external fixators. The objective is to retrospectively evaluate the results of the use of S53P4 bioglass for the adjunctive treatment of septic non-unions. Methods: We reviewed 18 patients with septic non-unions. The patients were preoperatively classified using the Non-union Scoring System (NUSS) and union outcomes were assessed by the modified radiographic union scale in tibial (RUST) fractures. Of the 18 patients treated, six underwent internal osteosynthesis and 12 were treated with external fixators in combination with bioactive glass grafting. Results: The patients had a mean NUSS score of 56.6 (standard deviation of 7.6) and fracture union was achieved according to the RUST score in 17 of 18 cases (94.4%), with a mean value of 10.2 (standard deviation of 1.0). One patient was lost to follow-up. Reevaluation using the modified RUST score was 12.3 (SD = 1.0), maintaining union of 17/18. Conclusion: The fracture union rate was high, according to the literature, as was control of infection. Level of Evidence IV, Case series.
A unidade teórico-prática da intervenção didático-formativa no contexto da docência
Authors: Franco Patrícia Lopes Jorge , Longarezi Andréa Maturano , Marco Fabiana Fiorezi De
Published: October 2019

Resumo: A temática abarca a unidade teórico-prática da ação didático-formativa na docência de uma professora de Matemática e de estudantes do ensino fundamental em uma escola pública. Pesquisa longitudinal à luz da teoria histórico-cultural, método materialista histórico-dialético, cuja orientação teórico-metodológica favorece que sujeitos inter-relacionem suas atividades de ensino e de estudo na intervenção didático-formativa. Neste artigo o objetivo é discutir como a organização do ensino para o desenvolvimento do pensamento científico-teórico dos estudantes se constitui como conteúdo-forma no processo de desenvolvimento dos envolvidos. Resultados apontam que a professora apresenta desenvolvimento da ação mental sobre a docência, oferecendo elementos didáticos capazes de orientar estudantes a pensar e agir mediante a essência dos conceitos científicos na Álgebra. Alguns alcançaram certo domínio dos meios e das ações mentais lógicas do movimento interno representado pelo conceito teórico de funções e de equações lineares e quadráticas, a partir da essência de elos e nexos que os compõem.
Peeking into students’ mental imagery: the Report Aloud technique in Science Education research
Authors: Trevisan Robson , Serrano Agostinho , Wolff Jeferson , Ramos Adriana
Published: October 2019

Abstract: The goal of this article is to present a qualitative methodological proposal for researching Science teaching. We produced the article based on premises of the Think-Aloud method and Depictive Gesture Analysis. Here, we report on the structuring of the Think-Aloud technique, a novelty within the scope of research in education and applications in the teaching of Chemistry and Physics. The main advantages of this approach is its potential to establish a link between verbal and body language, which is produced by the participants during data production through the dialogues proposed within this research. Therefore, the procedures in the study allow for a more accurate analysis because of the pieces of evidence obtained from speaking, writing, and the gestures for the identification of mental images formed by the students about the scientific concepts they have studied.
A Modelagem Matemática no contexto do estágio supervisionado segundo as compreensões de futuros professores
Authors: Oliveira Wellington Piveta , Kato Lilian Akemi
Published: October 2019

Resumo: Neste artigo, tecemos algumas reflexões acerca das compreensões dos estagiários quanto à inserção da Modelagem Matemática no Estágio Supervisionado. A interrogação que nos move: O que os estagiários que vivenciaram a inserção da Modelagem no Estágio compreendem sobre essa experiência? conduziu-nos ao desenvolvimento deste estudo qualitativo segundo a postura fenomenológico-hermenêutica, modo pelo qual emergiram as reflexões sobre essa inserção, na perspectiva dos estagiários. Reunimos depoimentos de estagiários que vivenciaram a experiência com a Modelagem no Estágio em uma universidade estadual paranaense e destacamos deles unidades de sentido, que, em um movimento de convergência, deram abertura a dois núcleos, os quais nos permitiram lançar as reflexões aqui empreendidas. Esse movimento nos mostrou que os estagiários reconhecem benefícios da Modelagem no contexto do Estágio como alternativa metodológica, caracterizando-se como uma configuração relevante para a formação inicial do professor. No entanto, destacaram obstáculos para poderem realizar o Estágio com Modelagem.
Introducción al análisis socio-ecológico a partir del mapeo colectivo del propio territorio: los usos por parte de distintos actores sociales y sus conflictos associados
Authors: Urdampilleta Constanza , Borón Carlos Ignacio , Fischer Sylvia , Ithuralde Raúl Esteban
Published: October 2019

Resumen: El presente trabajo expone una práctica de la materia “Ecología y Desarrollo” en el ámbito de una Facultad de ciencias naturales. El objetivo es fomentar la apropiación por parte del estudiantado del espacio del campus y de conceptos de conflictos socio-ambientales y sistemas socio-ecológicos. A través de un trabajo de debate y con el uso de imágenes aéreas, información bibliográfica, notas periodísticas, fotografías del lugar y el relato de un integrante del Vivero Comunitario Ciudad Universitaria, se reconstruyen históricamente los cambios en el paisaje y sus usos. Las dinámicas planteadas propiciaron la identificación de distintos actores involucrados, visualización espacial de los usos que estos hacen del espacio, y la identificación de diferentes conflictos. Esta herramienta didáctica y técnica resultó un dispositivo valioso para facilitar el diálogo entre distintos actores.