bluuebunny/crossref_metadata_2025 huggingface dataset:
MEKAN ALGISI İLE KENTSEL KİMLİK: PAZAR İLÇESİ ÖRNEĞİ
Authors: ALİ̇EFENDİ̇OGLU Yesim , GÜNEŞ Parla
Published: September 2023

Kent mekânı dinamik ve değişken bir yapıya sahiptir. Mekânın çözümlenmesi, geçmişten bugüne değişkenlik göstermektedir. Bu değişimler fiziksel, toplumsal, tarihsel, kültürel, ekonomik, politik ve idari faktörlerin bir arada değerlendirilmesi ile mümkündür. Faktörlerin tamamı ise mekânın asıl aktörleri olan bireyler, sivil toplum kuruluşları, sektörel bileşenler ve yerel yönetim erkleri ile şekillenmektedir. Mekânın kimlik algısı geçmişten geleceğe uzanan bütünlük ile analiz edilebilmektedir. Kenti doğru okuyabilmek ve aynı zamanda okutabilmek mekânın kültürel değerlere uygun olarak şekillenmesi, halkın yönetime katılımı, şehir planlama ilkeleri ve planlama çalışmaları, kentlilik bilinci, aidiyet olgusu gibi kavramların büyük rol üstlenmesi ile mümkün kılınmaktadır. Mekânın yönetim erkleri ise kültürel mirası korumak ve kent dokusunun katılımcı yaklaşımlar ile desteklenmesi konusunda ön plana çıkmaktadır. Çalışma kapsamında mekânın okunması amaçlanarak kentlinin mekân-kimlik algısı çözümlenmiştir. Mekânda öne çıkan alanlar, siyasi ve kültürel kırılma dönemleri, planlama çalışmaları ile mekândaki odak noktalarının yer değiştirmesi ve mekânın aktörlerinin kentsel algısı irdelenmiştir. Rize ili Pazar ilçesi örneği ele alınarak yapılan çalışmada geçmişten bugüne fiziki değişiklik gösteren mekân ele alınırken soyut anlamda mekân aktörlerinin algısı da anket çalışması ile desteklenmiştir. 1970’li yıllarda ilk çalışmalardan günümüze kadar süren planlama süreci mekânda fiziki değişimler gerçekleşmiştir. Planlama çalışmaları ile alınan kararlar doğrultusunda ticaret merkezi çevresinde yoğunlaşan kentin, sahil aksı boyunca doğu-batı doğrultusunda geliştiği görülmüştür. Yapılan ankette ise planlama döneminin hareketlilik gösterdiği 1980’li yıllar başlangıç alınarak; döneme tanıklık eden kişilerle mekân-kimlik algısı ölçülmüş, kentin kimliğini oluşturan unsurlar tespit edilmiştir.
Çocukluk Döneminde Maruz Kalınan İstismar Nedeniyle Travma Sonrası Stres Bozukluğu Yaşayan Bireylere Özgü Etkili Psikolojik Tedaviler
Authors: SEVER Melek , ALLAHVERDİ Fatima Zehra
Published: September 2023

Çocukluk döneminde yaşanan duygusal, fiziksel, cinsel ve ekonomik istismar kişiyi ruhsal yönde olumsuz olarak etkilemektedir. Bu istismarları yaşayan kişiler birden fazla psikopatolojiyi aynı anda geliştirebilirken bu kişilerde en sık rastlanan psikopatoloji Travma Sonrası Stres Bozukluğu (TSSB)’dur. Özellikle fiziksel ve cinsel istismar yaşayan çocukların bu bozukluğu geliştirme riski daha yüksektir. Bu çalışmanın amacı çocukluk döneminde maruz kalınan istismardan dolayı TSSB geliştiren bireyler için etkili, kanıtlanmış, güncel psikolojik tedavileri araştırmaktır. Cinsel istismardan dolayı TSSB geliştiren bireyler için kanıtlanmış müdahale teknikleri: Travma Odaklı Bilişsel Davranışçı Terapi (BDT), Diyalektik Davranış Terapi (DDT), Duygu ve Kişilerarası İlişkiyi Düzenleme Becerisi Eğitimi (STAIR), Travma için Duygu Odaklı Terapi (DOT), Göz Hareketleriyle Duyarsızlaştırma ve Yeniden İşlemleme (EMDR), Yeniden Senaryolaştırma (Imagery Rescripting, IR)’dır.
KAPSAYICI LİDERLİK VE PROAKTİF DAVRANIŞLAR: PSİKOLOJİK GÜVENLİĞİN ROLÜ
Authors: GÜLERYÜZ İlkay , SÜRÜCÜ Lütfi
Published: September 2023

İşletmelerin etkinliğini artırarak daha iyi bir işleyişe sahip olmaları için liderlik yaklaşımlarını yerinde ve hedefe yönelik kullanmaları önem taşımaktadır. Bu araştırma, kapsayıcı liderliğin çalışanların proaktif davranışlarına ve psikolojik açıdan güvenli hissetmelerine olan etkisine odaklanmaktadır. Bu maksatla kapsayıcı lider, proaktif davranış ve psikolojik güvenlik değişkenlerini içeren bir model önerilmiştir. Bu modelin test edilmesi için de İstanbul ve Ankara illerinde çeşitli sektörlerde faaliyet gösteren çalışanlardan anket aracılığıyla veriler toplanmıştır (N=381). Elde edilen veriler, SPSS- 27 ve AMOS-22 yazılımları kullanılarak analiz edilmiştir. Analizler sonucunda, kapsayıcı liderliğin hem proaktif davranışlar hem de psikolojik güvelik üzerinde ayrı ayrı anlamlı ve pozitif yönlü bir etkisinin olduğu ortaya konulmuştur. Ayrıca literatürde daha önce ele alınmamış olan, psikolojik güvenliğin, kapsayıcı liderliğin proaktif davranışlara etkisindeki aracı rolü de test edilmiş olup, aracı (mediate) rolün olduğu gözlemlenmiştir. Böylece önerilen model literatürde özgün bir konuma gelmektedir. Analizler sonucunda elde edilen bulgular, kapsayıcı liderliğin başta proaktif davranışlar olmak üzere etkilediği örgütsel davranış başlıklarını zenginleştirmektedir. Ayrıca bu bulguların hem akademik literatüre hem de işletme yöneticilerine uygulamalar esnasında katkı sağlayacağı değerlendirilmektedir.
Establishment of an erosion-control plant cover in a sand pit under Arctic conditions using sewage sludge
Authors: Lusis A. V. , Ivanova L. A. , Gorbachyova T. T. , Rumyantseva A. V.
Published: September 2023

This paper presents the findings of a prolonged field studies that ained to assess the feasibility of using the sewage sludges (SS) form a regional water and wastewater services enterprise to expedite the establishment of a resilient erosion-control plant cover in sand pits located in the Arctic region of the Russian Federation. The study confirms the beneficial impact of the SS on the seed germination, subsequent growth, and development of plants.The study shows that SS can be used in two ways: first, by applying a continuous layer measuring 5 to 10 cm thick on the soil surface or by fragmentarily applying a layer 2–3 cm thick. Second, through early-winter sowing of seeds directly on the soil surface (under the SS layer) or on top of the sewage sludge. In both cases, an annual enhancement of the qualitative and quantitative parameters of the artificially formed stand of grass was observed. This included a significant increase in its height and density, biomass, foliage cover, and thickness of the formed sod, in contrast to the reference sample.The present study investigates the characteristics of the floristic composition of the phytocenoses formed in a sand pit. The findings demonstrate that the use of sewage sludge (SS), regardless of the quantity and application method, accelerates the restorative succession in the sand pit. The thick stand in the experimental variants, resulting from the attraction of pioneer vegetation, promotes the complexity of its structure and species composition, rapid vegetation of inner bare areas, and the emergence of natural phytocenoses elements that are specific to the zonal type of vegetation. Additionally, the use of SS stabilizes erosion processes in the study ares. Consequently, the plant community formed in the experiment using SS can be classified as ecologically sustainable, with the potential for independent existence and further development.These results can serve as a foundation for monitoring efforts and the development of measures to optimize the vegetation of such ecotopes.
Reviewer Acknowledgements 2023
Authors: Terrazas Teresa
Published: September 2023

Acknowledgments to Reviewers
Ocupational noise and its influence in the accidents and work absenteeism in Tal S.A, Trujillo-Peru, 2021-2022
Authors: Landeras Pilco María Isabel
Published: September 2023

The influence of occupational noise in the accident rate and work absenteeism in the company Tal S.A., Trujillo-Peru, 2021-2022 was stablished. As a working day is generally "complex" and due to the difficulty of the "operations division", the "sampling during work" strategy was chosen. Due to the process characteristics, the positions are "fixed and mobile" and within their complexity there are many operations in which its time duration isn’t fixed. Out of the 840 workers that work in the production process, 414 worked in the stages of greatest risk (1 to 18) and constitute a similar exposure group (GHE). Six weeks of measurement (one day/week) were scheduled, corresponding to 415/5 = 82.8 º 83 workers per measurement. Three measurements were made every 15 seconds. The variations fluctuated between 3 and 5 dB(A), taking the average value. Prior to the measurement, the worker described his job, facilitating the location and identification of potential risk exposures (extreme noise that would lead to hearing loss). Regarding the work absenteeism indicator, an average incidence of 20% was registered in the company Tal S.A., in the months of February, March, May and November.
Heat Stress in Vegetables: Impacts and Management Strategies – A Review
Authors: Oyebamiji Yusuf Opeyemi , Abd Aziz Shamsudin Noraziyah , Asmuni Mohd Ikmal , Yusop Mohd Rafii
Published: September 2023

Global climate change has not only caused a significant rise in the average temperature around the world but has also threatened crop productivity and food security. Heat stress disrupts various plant physiological and biochemical processes, such as inhibition of growth and development, reduction of photosynthesis rate and nutrient uptake, consequently causing yield losses. The destructive effects of heat stress are expected to worsen in the coming years. Thus, it has become imperative to understand how vegetables respond and adapt to heat stress in order to improve their heat tolerance ability. Various approaches have been adopted to enhance heat stress tolerance in vegetables, including modifying cultural practices and crop improvements through several breeding methods. This review gives comprehensive and up-to-date information on the effects of heat stress on vegetables; and existing as well as emerging methods adopted to enhance heat tolerance in vegetables. It also provides a brief overview of a new method called speed breeding, which can be leveraged to fast-track the breeding process for developing heat stress-tolerant vegetables.
Pollen and Seed Morphology of Cleome Species (Cleomaceae) in Vietnam
Authors: Nguyen Nga Thi Thu , Chaudhary Ritesh Kumar , Tu Tan Quang , Mau Hoang Chu , Nguyen Quan Huu , Do Hai Van , The Tran Bach , Lee Joongku , Lee Changyoung , Danh Sy Thuong
Published: September 2023

Cleomaceae is a family that includes 18 genera distributed worldwide in tropical and temperate regions. Cleome L. is the largest genus having 207 species, widely distributed in tropical and subtropical regions (POWO 2019). In Vietnam, the genus is represented by four species Cleome rutidosperma DC., C. houtteanaSchltdl., C. viscosaL. and C. gynandraL. The present study documents the pollen and seed characteristics of all four species of Cleome in Vietnam, and the data obtained using light microscope and scanning electron microscope are analyzed considering their importance in taxonomic delimitation and understanding their phylogenetic relationship. The results indicated a close relationship between different pollen and aperture types. The striking differences between the pollen shapes among different species of Cleome could be useful in taxonomic and evolutionary studies. Similarly, seed shape and surface characters provided important clues for their delimitation. Based on the pollen and seed morphological characteristics, a taxonomic key has been provided for easy identification of the Cleome species in Vietnam.
Potential of Bacillus spp. Isolated from Food Waste Compost for Controlling Rice Diseases
Authors: Meehae Usmana , Kumngen Aunkamol , Chotigeat Wilaiwan , Suwannarat Sudarat , Anuchan Sujunya , Whankaew Sukhuman , Leunram Siwapong , Karrila Seppo , Iewkittayakorn Jutarut
Published: September 2023

Bacterial leaf blight, bakanae and blast are severe, economically damaging rice diseases caused by Xanthomonas oryzae, Fusarium fujikuroi, and Magnaporthe oryzae, respectively. Bacillus spp. have been applied as bioactive, eco-friendly agents to control these diseases. In this study, five antagonistic strains isolated from food waste compost, namely B. subtilis strain BS, B. amyloliquefacien strain C2-1, B. tequilensis strain 1-BA, B. licheniformis strain 2-BA, and Lysinibacillus. sp strain 3-BA were tested for their efficacy againstrice diseases. The inhibition of X. oryzae was tested by paper disc diffusion, while the inhibitions of F. fujikuroi and M. oryzae were tested in dual cultures. It was found that B. amyloliquefacien strain C2-1 gave the widest clear zones. At 24 h, 48 h, 72 h and 7 days, the strain had produced zones of inhibition against X. oryzaeof 7.41±0.65, 7.9±0.20, 8.8±0.65 and 8.90±0.12 mm, respectively. B. amyloliquefacien strain C2-1 also reduced the growth of the fungal rice pathogens F. fujikuroi and M. oryzae, achieving 98.79% and 97.74% inhibitions, respectively. B. amyloliquefaciens strain C2-1 was also effective against X. oryzae, F. fujikuroi, and M. oryzae in the greenhouse. Fourteen days after spraying rice plants with the B. amyloliquefacien strain C2-1, infections with X. oryzae, F. fujikuroi, and M. oryzae were inhibited by 60%, 37%, and 25%, respectively. The results suggested that B. amyloliquefacien strain C2-1 can be used as a biocontrol agent against bacterial leaf blight, bakanae, and rice blast diseases.
Adsorption of Ciprofloxacin Using Composite Film from PVA, Agarose and Maltodextrin
Authors: Hoang Bich Ngoc , Huong Dieu Tran , Quyen Ngo Thi Cam , Nguyen Thi Nhu Dung , Bach Long Giang
Published: September 2023

Antibiotic resistance is one of the most alarming problems today. Therefore, composite membranes have been widely applied for the removal of antibiotics from water. PVA/Agarose/Maltodextrin films have been synthesized by casting with various component ratios. They were evaluated for characteristics through moisture, solubility, expansion, and BET results. The results showed that PVA/Agarose/Maltodextrin films exhibited the best viability in the aquatic environment through low solubility (68.88% ± 0.03), high swelling (431.77% ± 5.89) and pore volume (0.034969 cm³/g). The adsorption capacity of PVA/Agarose/Maltodextrin was tested for several antibiotics such as Ciprofloxacin, Tetracycline, Oxy-Tetracycline, and Chloramphenicol. The results showed that Ciprofloxacin was removed by the PVA/Agarose/Maltodextrin films better than other antibiotics. The highest antibiotic adsorption was obtained at 20 min, temperature of 30 °C, dosage of 2 g/L, pH 6, and antibiotic concentration of 40 mg/L. Ciprofloxacin adsorption was predicted through adsorption kinetic and isothermal models. The compatibility of the Pseudo First Order kinetic and Dubinin-Radushkevich isothermal has shown that adsorption takes place according to a physical adsorption mechanism with electrostatic interactions on the surface of the material. The maximum adsorption capacity recorded at 4.48 mg/g based on the Dubinin-Radushkevich isothermal.
Signless Laplacian Energy of Interval-Valued Fuzzy Graph and its Applications
Authors: Romdhini Mamika Ujianita , Al-Sharqi Faisal , Nawawi Athirah , Al-Quran Ashraf , Rashmanlou Hossein
Published: September 2023

An interval-valued fuzzy graph (IVFG) emanates from a fuzzy graph (FG) where the membership is given in interval form. This framework give the user more flexibility in dealing with fuzzy information. In this paper, the signless Laplacian matrix of an interval-valued fuzzy-directed graph is defined. The eigenvalue, spectrum, spectral radius, and energy of an interval-valued fuzzy-directed graph associated with the signless Laplacian matrix are reported. In addition, the lower bound of the signless Laplacian energy in this graph is highlighted. Finally, these tools are employed to build an algorithm that helps in solving some real live problems.
EU Representations in Portuguese Media and Populism: Embodying Political Antipodes?
Authors: Freire Maria Raquel , Santos Sofia José , Crivelente Moara Assis , Bezerra Luiza Almeida
Published: September 2023

Mass media mediate different publics, thus being crucial in constructing political reality. By selecting which topics are covered (agenda), which voices are heard, or how social and political issues/actors/dynamics are represented (priming and framing), mass media impacts how political conversations and processes unfold. Acknowledging the increasing mediatisation of politics, this article zooms into media texts of the Portuguese media during a complex political period that included national elections to explore how populism as a term, label, or topic was used and/or co-opted to create and negotiate political EU representations. Building on a historical perspective and using critical thematic analysis, this article argues that populism was used in the media and by the media as a discursive mechanism of political positionality and/or delegitimisation or criticism of political actors, agendas, or moves, thus making populism and the EU co-constitutively used as embodying political antipodes and making the EU work as a discursive buffer concerning populism in the country.
Chilean neurorights legislation and its relevance for mental health: Criticisms and outlook
Authors: Cornejo-Plaza Isabel
Published: September 2023

Background. Recently, the academic world has established a series of reconfigurations of emerging human rights, in order to safeguard the mental integrity of people exposed to neurotechnologies. The recommendations of different stakeholders and a literature review support regulation of these technologies. There are different proposals for regulation, some in soft law and others in objective law. The type of regulation chosen can have repercussions on clinical practice, research, and public policy. The constitutional enactment of neurorights in Chile has been criticized in the academic fields of neuroethics and law as having potential negative effects on mental health research. Objective. To analyze in light of the available literature whether the construction of neurorights could create ethical conflicts in the field of mental health, or if it could offer protection against the disruptive use of various neurotechnologies. Method. This analysis included a narrative review of studies included in the PsycInfo, Springer, JSTOR, Medline, Scopus, PubMed, CINALH, and Web of Science databases, without restrictions on language or year of publication. Results. The enactment of neurorights as hard law is found not to be detrimental to the field of mental health. Discussion and conclusion. This article argues that the regulation of neurorights does not threaten the framework of an ecosystem that uses neurotechnologies. On the contrary, such regulation offers protections to people within the complex system of neurotechnologies.
THE PECULIARITIES OF THE MAIN ORE-FORMING COMPONENTS DISTRIBUTION IN THE FILIZCHAY FIELD OF THE SOUTHERN SLOPE OF THE GREATER CAUCASUS
Authors:   Baku State University, Baku, Republic of Azerbaijan, Sattar-zadeh N. , Imamverdiyev N. ,   Baku State University, Baku, Republic of Azerbaijan
Published: September 2023

The article has been devoted to the distribution of the main ore-forming components in Filizchay field of the southern slope of the Greater Caucasus. 3D model of the mineral elements of Filizchay field has been using "Leapfrog GEO" program. Analysis of the isothicknesses map clearly shows that the eastern flank of the deeper, shallow dipping part of the deposit is characterized by the greatest thickness where its thickness exceeds practically universally average value of this parameter according to the field. It has been found that zinc and lead distributions repeat practically each other. The western half of the body differs sharply from the eastern half by stable high (more than average value) contents. The overwhelming majority of zinc concentrations minimums and nearly all lead minimums are located in the eastern half which is generally characterized by the contents being below average. According to the copper concentrations distribution the deposit is very clearly divided into two parts – the southeastern part being thicker and richer and the northwestern part being relatively less thick and with contents being below average according to the field. The comparison of silver and lead isocontents' maps indicates a close relationship of both elements as evidenced by the very similar nature of their spatial distribution within the deposit. As well as for lead one can be generally distinguish two halves in it that are generally differed from each other in the intensity of the silver
mineralization – the northwestern being richer and the southeastern being relatively poorer. The boundary between these parts repeats mainly the boundary determined for lead not only according to the spatial position but also according to the main details of the outline. All the maxima of the silver mineralization are located in the northwestern half of the field, the most of which are located on the upper horizons. According to the intensity degree of the zinc, lead and silver mineralization manifestation in the deposit, two parts can be distinguished: the western one is richer where almost all maxima are concentrated and the eastern one is poorer which accounts for the most of the minima. The boundary between them passes approximately in the middle part of the body from the upper to the lower horizons; it nearly coincides with the direction of its fall and it is distinguished by complex outlines. The frequent isolines repeatability of the zinc and lead contents, the close spatial position of their maxima centers suggest a close positive correlation between them.
CONTROL SAMPLES USING FOR QUALITY ASSURANCE AND CONTROL (QA/QC)
Authors:   Geological Service Company LLC, Kyiv, Ukraine, Bariatska N. , Sergeieva S. ,   Geological Service Company LLC, Kyiv, Ukraine
Published: September 2023

Іn geological exploration, the quality of the data underlying of resource and reserve estimation is critically important. According to various international regulations and current world best practices, Quality Assurance and Quality Control (QA/QC) programs are a necessary part of geological exploration. Quality Assurance (QA) is used to avoid the problems with quality, Quality Control (QC) is aimed at detecting them in case of their occurrence, and together they form the overall Quality System – QA/QC. The article considers the main stages of the history of QA/QC development, which begins in the Middle Ages and continues in our time.
Control samples used to control analytical tests have different types and purposes / functions: standards, preparation blanks, coarse blanks, analytical blanks, field duplicates, coarse duplicates, pulp duplicates and umpire laboratory control. Their amount and ratio is the main topic of the research. According to the published data of nine different authors, the recommended control sample amount of each type is different. On average, the amount of control samples of all types is about 20% of the total number of routine samples.
In order to highlight the current state of the issue, the authors of the article have analyzed 111 QA/QC programs for 87 ore projects according to the public reports disclosed by the issuers of the Toronto Stock Exchange. So, in practice, the control sample amount does not necessarily reach the recommended 20 % and is slightly more than 16 %.
The main conclusions regarding the amount and ratio of control samples can be presented as follows: (1) the general increasing trend in the amount and variety of control samples is observed; (2) among the control sample types, the so-called standards are most often used, and the least used are coarse blanks; (3) the control sample amount and variety also depends on the mineral type; (4) at more advanced exploration stages of the project, the control sample relative number usually increases, but in some cases it may decrease if the results of the previous stages are satisfactory, and the methodology and laboratory are not changed.
“Rice bodies” symptoms on magnetic resonance imaging of the shoulder in a patient with rheumatoid arthritis
Authors: Ageeva Sofia F. , Filatova Daria A. , Mershina Elena A. , Sinitsyn Valentin E.
Published: September 2023

The “rice bodies” symptom on magnetic resonance imaging of the shoulder joint in patients with rheumatoid arthritis is a rare but specific finding characterized by the presence of multiple small, round, rice-grain-like structures in the synovial fluid of the joint, synovial pouches, or sheaths. The etiology of the “rice bodies” is still not fully understood. They are suggested as the result of microinfarcts of the synovial membrane in patients with rheumatoid arthritis or other inflammatory joint diseases. Clinically, the “rice bodies” symptom may cause pain, but not in every case. Among radiological diagnostic methods, magnetic resonance imaging is the leading method for the detection of rice bodies. This article presents a clinical case of “rice bodies” symptoms diagnosed by magnetic resonance imaging in a patient with a long history of rheumatoid arthritis who presented with a painless enlargement in the left shoulder. Computed tomography and magnetic resonance imaging of the left shoulder could detect “rice bodies” as a manifestation of an underlying disease and determine further treatment techniques.
Delphi method to determine a list of questionnaire-assessed parameters in the follow-up of patients with inflammatory bowel disease
Authors: Shumskaya Yuliya F. , Akhmedzyanova Dina A. , Mnatsakanyan Marina G. , Kolosova Ksenia Y. , Tashchyаn Olga V. , Yurazh Marta V. , Reshetnikov Roman V.
Published: September 2023

BACKGROUND: Patients with inflammatory bowel disease often require lifelong follow-up by a clinician. Telemedicine monitoring is a promising area of such healthcare services, often based on the evaluation of patients’ remote questionnaire results by a medical practitioner.
AIM: To define, using the Delphi method, a list of questionnaire-assessed parameters for monitoring and treating patients with IBD.
MATERIALS AND METHODS: The study was conducted in three stages. An electronic survey form was created to collect information, ensuring that the respondent’s experience was included when completing the survey. In the first stage, respondents answered an open-ended question about what parameters assessed by questionnaires should be monitored in patients with IBD. In the second stage, participants answered the same question but selected any number of items from a list. In the third stage, the responses were analyzed. The primary endpoint was a consensus on each parameter, defined as 75% respondent agreement.
RESULTS: The study had 15 participants, 13.3% of whom were male. Of all respondents, 46% worked in an outpatient setting, whereas 54% worked in an inpatient setting. Their ages ranged from 25 to 53 years, with 53% of the participants having 1–4 years of experience and 47% having 17–29 years of experience. None of the parameters reached a 75% agreement level based on the results of the first stage. In the second stage, respondents reached a consensus on 72% of the parameters. No relationship was found between respondents’ age, sex, years of experience, or job settings and responses in the first and second stages.
CONCLUSIONS: The final list of parameters recommended for evaluation during the monitoring and treatment of patients with IBD included abdominal pain, frequency of defecation and stool quality, presence of pathological stool impurities, body temperature, joint/muscle pain, sleep quality, anxiety, depression, work capacity for employed/ability to attend lessons for students, energy and quantity of vigor, fixation on the disease, patients’ general evaluation of their quality of life, and treatment adherence.
Clinical and pathogenetic justification of the use of azathioprine in the treatment of progressive non-segmental vitiligo
Authors: Vovdenko Kseniia A. , Olisova Olga Yu. , Smirnov Konstantin V. , Svistunova Daria A. , Lomonosov Konstantin M.
Published: September 2023

BACKGROUND: Vitiligo refers to acquired hypomelanosis, characterized by the appearance of depigmented spots on the skin. The search for new vitiligo treatment approaches, which would simultaneously have a pathogenetic focus on the therapy of this disease and at the same time have a safe spectrum of side effects, is relevant today.
AIM: to evaluate the clinical and laboratory efficacy of azathioprine in progressive non-segmental vitiligo compared with NB-UVB monotherapy.
MATERIALS AND METHODS: 60 patients with progressive non-segmental vitiligo were divided into 2 equal groups: group 1 received azathioprine in combination with NB-UVB, group 2 received NB-UVB monotherapy. The follow-up period was 6 months. The effectiveness of therapy was evaluated based on the dynamics of the Vitiligo Area Scoring Index (VASI), dermatological quality of life index (DLQI), as well as the titers of proinflammatory cytokines IL-1, IL-2, IL-6, IL-8, IFN-, TNF- and S100 protein in serum blood.
RESULTS: In the azathioprine + NB-UVB group, compared with the control group, a statistically significant prevalence of VASI and DLQI indices reduction was observed. (Me -61.70%, Q1Q3: -75.14-47.08%, p 0.001; Me -55.83%, Q1Q3: -67.80-40.29%, p 0.001). The dependence of the quality of life of patients on the prevalence of the skin process was noted (p 0.001). There was a statistically significant relationship between the activity of the skin process and the S100 protein in the blood serum of patients with vitiligo. (p 0.05) In addition, the analysis of the dynamics of immunological parameters of the main group compared with the control group showed a more significant decrease in the level of cytokines, as well as S100 protein in blood serum (p 0.001).
CONCLUSION: The combination of azathioprine and NB-UVB is effective and safe, helps to stabilize the skin process and stimulate the repigmentation of foci, significantly improving the quality of life of patients, contributes to the normalization of immunological parameters, leading to an earlier stop of the progression of the skin process.
Impact of combination therapy on Ki-67 and Bcl-2 expression in psoriasis
Authors: Melikova Nigina I. , Tashkenbaeva Umida A.
Published: September 2023

BACKGROUND: Psoriasis is a chronic inflammatory immune-mediated disease characterized by an increased rate of keratinocyte division. Modern ideas about the immunopathogenesis of psoriasis, systemic inflammation and manifestations, comorbid conditions bring to the fore the question of the rational choice of therapy in patients with moderate and severe psoriasis.
AIM: to study the effect of the combined use of PUVA therapy and methotrexate on the expression levels of receptors for the proliferation marker Ki-67 and the anti-apoptotic protein Bcl-2.
MATERIALS AND METHODS: The study included 110 patients with moderate to sеvеrе psоriаsis,divided into 2 groups: the first group received PUVA therapy in combination with methotrexate (Mt); the second group received methotrexate (Mt) monotherapy. Skin biopsies were taken from the affected areas in 10 patients from the 1st group before and after therapy for immunohistochemical study to determine the level of expression of Ki-67 and Bcl-2. Healthy skin bioptats were taken from patients operated on for appendicitis and used as the control samples.
RESULTS: An immunohistochemical study revealed a statistically significant increase in the initial indicators of the expression level of Ki-67 and Bcl-2 in all patients with psoriasis compared with the control group. As a result of the combined therapy, there was a significant decrease in the expression of Ki-67 and Bcl-2.
CONCLUSION: The combined method of treatment of patients with psoriasis has an immunosuppressive effect, as evidenced by a significant decrease in the expression of the proliferation marker Ki-67 and the apoptosis inhibitor Bcl-2.
Modern view on rosacea: Topical issues of epidemiology, pathogenesis and therapy. Literature review
Authors: Aleksandrova Olga A. , Dubenskiy Valeriy  V. , Muraveva Ekaterina S. , Tenyaev Maksim A.
Published: September 2023

Rosacea is a multifactorial dermatological disease that is widespread throughout the world, initially manifested as a cosmetic defect, and in the absence of systemic and topical therapy leads to a change in the structure and functions of the facial skin.
Patients with rosacea often seek medical attention, as these aesthetic problems impair their quality of life and contribute to the development of social and psychological problems. Chronic stress is often the cause of the development of social maladaptation, which occurs because of a constant feeling of self-doubt, own inferiority, and anxiety. Anxiety and chronic depression can cause even minor manifestations of rosacea, as it is localized on the skin of the face. Dermatosis often manifests itself in women older than 30 years, under the influence of multiple trigger factors, has a chronic relapsing course.
Understanding the pathophysiology and the use of combined therapies can improve the effectiveness of therapy in patients with rosacea, achieve and prolong clinical remission, identify trigger factors and possible prevention. This explains the need to study rosacea not as an independent dermatosis, but as a sign of more significant disorders that can lead not only to social and aesthetic problems, but also affect the general health of the patient.
On the issue of tolerability and safety of phototherapy in patients with psoriasis
Authors: Olisova Olga Yu. , Grekova Ekaterina V. , Smirnov Konstantin V. , Yazkova Olga S. , Koriakin Danila A. , Melikova Nigina I.
Published: September 2023

BACKGROUND: Phototherapy using different wavelengths of the ultraviolet (UV) spectrum has been successfully used to treat a variety of dermatoses. Along with the positive effects of this intervention, there are both acute and long-term side effects that should be taken into account by the clinicians.
AIM: to study the tolerability and safety of phototherapy (PUVA and UVB-311 nm) in patients with moderate to severe psoriasis.
MATERIALS AND METHODS: There were 920 patients with psoriasis under our supervision from 2005 to 2021, of which 756 (82%) patients suffered from psoriasis vulgaris, 36 (4%) ― guttate psoriasis, 73 (8%) ― exudative psoriasis, 55 (6%) ― inverse psoriasis. 249/920 (27%) were diagnosed with psoriatic arthritis. Patients with moderate psoriasis received 311 nm UVB therapy (n=473), with severe psoriasis ― PUVA therapy (n=447).
RESULTS: Out of 920 patients with psoriasis during the entire follow-up period, 385 (41.8%) noted one or more early side effects, which were short-lived and disappeared after the end of the PUVA course if the recommendations were followed. Among the early side effects that occurred during the procedures from taking a photosensitizer, the most common were transient nausea, vomiting, dizziness, headache, transient increase in hepatic transaminases. Side effects from the action of ultraviolet rays were reduced to the manifestation of itching, photodermatitis in the form of erythema, photodermatitis in the form of blisters, photoallergic reaction in the form of papular rash, dry skin, photoconjunctivitis, herpes simplex and even photoonycholysis. Patients treated with UVB-311 nm phototherapy complained on xerosis of the skin, itching, photodermatitis in the form of erythema, burning of the skin as early side effects. Long-term side effects in patients treated with PUVA therapy included lentigo (persistent mottled pigmentation), growth of melanocytic neoplasms, PUVA keratosis. In 11 (2.3%) patients with psoriasis who received UVB-311 nm therapy, new nevi appeared. In 42 (9.6%) patients treated with PUVA therapy and in 17 (3.8%) patients treated with UVB-311 nm, signs of photoaging were detected as well. In our study, only 1 (0.2%) patient was diagnosed with facial skin basal cell carcinoma, who received 5 courses of PUVA (119 procedures).
CONCLUSION: Our study showed that side effects, especially long-term ones, were fewer and significantly less pronounced in patients treated with UVB-311 nm therapy. Comparing the benefits and risks of phototherapy sessions, we can conclude in favor of the effectiveness, good tolerability and safety of PUVA and UVB-311 nm therapy for the treatment of patients with moderate to severe psoriasis. A dose-dependent effect of photoaging was established: the more phototherapy courses were received, the more pronounced the signs of photoaging were, especially after PUVA therapy.
Photogallery. Juvenile hemangiomas
Authors: Dubensky Vladislav V. , Dubenskiy Valeriy V.
Published: September 2023

Juvenile hemangiomas can occur from the first months of life, with the prevalence of superficial juvenile hemangiomas (76.1%), more often solitary (83.3%).

Female infants predominate among the patients, with a 2:1 ratio.

Localization on the skin of the face and scalp is determined in 30% of cases; the remaining juvenile hemangiomas are located on the skin of the trunk and extremities.

Hemangiomas are mostly peripheral and small in size (1020 mm), superficially and up to 5 mm deep.

The most frequent complication of juvenile hemangiomas is ulceration, both as a consequence of exophytic growth and treatment methods.

The predominance of arterial intramedullary blood flow was found at ultrasound diagnosis, however, variants of 2-phase blood flow can also occur, which requires additional ultrasound examination of all cases of juvenile hemangiomas.

We offer the publication of a photo gallery on this problem.
Necrobiosis lipoidica of the scalp
Authors: Teplyuk Natalya P. , Grabovskaya Olga V. , Rogozina Varvara A.
Published: September 2023

Necrobiosis lipoidica is a chronic granulomatous skin disease of a vascular-exchange nature from the group of localized skin lipoidosis, accompanied by the development of degenerative changes in the connective tissue.
The reason for the development of necrobiosis lipoidica is unknown, but the most common theory remains the theory of vascular disorders, including the deposition of immune complexes (IgM, complement component C3), microangiopathic changes (deposition of a glycoprotein in the walls of blood vessels), as well as other combinations of inflammatory and structural changes leading to collagen degeneration and decreased perfusion and oxygenation of the skin. Necrobiosis lipoidica occurs in association with systemic diseases (sarcoidosis, autoimmune thyroiditis, inflammatory bowel disease, such as ulcerative colitis, and rheumatoid arthritis) and can also occur in otherwise healthy individuals. Necrobiosis lipoidica is closely associated with diabetes mellitus.
The predominant localization of necrobiosis lipoidica is tibial surface of the legs. Atypical localization is: skin of the scalp and face.
Clinical polymorphism of necrobiosis lipoidica, possibility of transition from one form to another, its combination with other dermatoses can pose difficult diagnostic questions for the doctor.
The article describes our own clinical observation of a patient with complaints of rashes on the skin of the legs and scarring alopecia in the scalp. The focus on the scalp had a tendency to grow and signs of development of scarring alopecia. According to the results of a biopsy performed at the Rakhmanov Department of Skin and Veneral Diseases, I.M. Sechenov First Moscow State Medical University, was diagnosed with "Necrobiosis Lipoidica". The case was interesting due to the extreme rarity of rashes on the skin of the scalp and the absence of dermatoscopic features of lesions in this area. Due to ongoing therapy for a month, there was a positive effect in the form of a lack of growth of existing plaques and the appearance of new ones, a decrease in the brightness of the color of the rash, a partial regression with an outcome in residual hyperpigmentation.
Thus, despite the absence of a gold standard in the treatment of necrobiosis lipoidica, the most well-studied group of drugs for the treatment of the disease at the moment are glucocorticoids, which confirms our experience. Therapy of patients with necrobiosis lipoidica should be carried out by an interdisciplinary team (dermatovenereologist, endocrinologist, therapist).
Chronicles of A.I. Pospelov Moscow Society of Dermatovenerologists and Cosmetologists (MSDC was founded on October 4, 1891) Bulletin of the MSDC meeting N 1152
Authors: Yakovlev Alexey B. , Maximov Ivan S.
Published: September 2023

On April 18, 2023, the 1152nd meeting of the Moscow Society of Dermatologists and Cosmetologists named after A.I. Pospelov took place. The meeting was held in a face-to-face format. There were 115 participants in total. Ac-cepted as a member of the MSDC 1 person.

Two reports are presented in the clinical part of the meeting: clinical variations of the course of skin sarcoidosis: the mini-lecture describes 8 clinical cases of cutaneous sarcoidosis; Kaposi's sarcoma in a 24-year-old patient with positive antibodies to cytomegaly and EpsteinBarr viruses.

Three reports were presented in the scientific part of the meeting: The possibilities of im-proving the effectiveness of onychomycosis therapy (speaker I.S. Maximov, Sechenov University); The use of botulinum toxin type A for the correction of erythematous-telangiectatic subtype of rosacea (speaker A.O. Yakovleva, State Scientific Center of Dermatovenerology and Cosmetology); A post-graduate student of the Department of Dermatovenereology of the Peoples' Friendship University of Russia Aun Rami Yusefovi made a report on targeted therapy of children with moderate and severe forms of atopic dermatitis (co-speakers ― Prof. E.A. Batkaev, Prof. V.Yu. Ujuhu).
Author’s agency in a research article: From the grammar of language to the grammar of communication
Authors: Sheypak S. A.
Published: September 2023

Introduction. Writing for publication has been developed for two last decades as an independent field of research to help authors publish their research articles. Starting from the assessment that preparing the publication in a journal is an academic activity that requires learning to construct the author’s positioning in the manuscript, this paper points out the shortage of professionals to assume institutional organisation of training courses in Russia.

Aim. This paper aims to suggest a framework for informal practices based on autonomy and the collective organisation of authors to construct an authorial position in the manuscript or author’s agency toward a target journal.

Methodology and research methods. Various approaches applied in this paper are based on activity theory: situated learning, Change Laboratory, and expansive learning.

A review of Russian and foreign research in writing for publication shows that only one of the three types of authorial agency, that is, transformative agency, might help the author to prepare a manuscript for publication in a target journal. The framework needed for emerging author’s transformative agency re-conceptualises the model of the Change Laboratory for situated learning that aims at the author’s socialisation in the discursive practices of a target journal. Situated learning for writing for publication is based on the principles of the Change Laboratory: collectivity; double stimulation; overcoming the contradiction by ascending from the abstract to the concrete.

Results. A framework for three cycles of expansive learning aimed at the emergence of the author’s agency toward a target journal has been developed. The first cycle allows selecting a journal and revealing its implicit rules for manuscript production. The second cycle is focused on step-by-step manuscript revisions. Finally, a change of journal and/or author whose manuscript is discussed involves the third cycle of expansive learning.

Scientific novelty. The paper considers manuscript production for publishing in a journal as an academic activity requiring deliberate training in native and foreign languages. The framework for three cycles of expansive learning in writing for publication conceptualises the publication as the author’s participation in social practices involving the journal as a discursive community.

Practical significance. The framework suggested in this paper for emerging transformative agency in writing for publication might imply an alternative to the institutional training courses. Three cycles of expansive learning aim to develop the author’s publication competence and improve the quality of research articles.
Coupled synergistic development of the sports industry and urban park ecological environment
Authors: Liy Manrong , Zhang Miao
Published: September 2023

The quality of sports and leisure has received the attention of local sports departments. The construction of sports parks has become a new hot spot to enhance the image of the city and develop sports. Therefore, this paper studies the coupled and synergistic development of the sports industry and urban park ecology. First, the current situation of urban sports parks in China is analyzed. Then the affiliation numerical method was introduced into the evaluation of park ecology. Finally, we calculate the acquisition index and evaluation and use it to analyze the ecological and environmental effects of plant communities. The results showed that in Manduhai Park, Hohhot, the temperature change of plant communities first rose and then slowly decreased, with the highest temperature at 4 pm and the lowest at 8 pm, and the cooling rate was 3.34%~5.05%. The relative humidity was highest at 8:00 a.m. and lowest at 4:00 p.m., with a humidification rate of 1.82% to 12.18%. Wind speed is the highest at 12:00 noon and the lowest in the morning and evening; the human body feels the best comfort in the morning at 8:00, and feels uncomfortable around 12:00 and 16:00, with a variation range of 71.77±2.73 to 73.19±2.54; the research found that 42% of the visitors chose leisure and sports activities; followed by 39% for entertainment and games, and 12% for cultural activities again. Thirty-one percent of the visitors were satisfied with the leisure and sports facilities, 31% thought they were average, 28% reached only basic satisfaction, and 10% were not satisfied with the leisure and sports facilities.
The Role of Income Smoothing on Financial Performance Indicators
Authors: Khzer Karzan Adnan , Sabir Jaf Rizgar Abdullah
Published: September 2023

The primary objective of this study is to determine whether income smoothing procedures have an impact on the financial performance of return on assets (ROA) and return on equity (ROE). Data for this study came from a sample of banks that are listed on the Iraq Stock Exchange. The research sample consists of banks listed between 2015 and 2019 on the Iraq Stock Exchange. The model estimate is done using the panel data approach. Five banks match the required requirements, and the samples were chosen using a purposive sampling technique. This study employs Miller's model to distinguish between banks that used income smoothing and banks that did not, as well as certain statistical techniques to examine the data. Two indices of financial performance—return on assets (ROA) and return on equity (ROE). Were used to compare the performance of smooth and non-smooth income banks and the variations in the influencing variables that influence each. The findings of this study demonstrate that return on assets (ROA) and return on equity (ROE) have a considerable impact on income smoothing procedures, while variable volume has a significant positive impact as well. In this study, we observed statistically significant differences between banks with and without smooth income in terms of their returns on assets (ROA) and returns on equity (ROE). We found a statistically significant positive relationship between bank size, financial success, and income smoothing in our study.