bluuebunny/crossref_metadata_2025 huggingface dataset:
O uso da realidade virtual em adultos com traços de transtorno de déficit de atenção e hiperatividade
Authors: Lemos Hugo Ferreira , Freitas Ana Claudia Mota de , Val Sabrina Nayara de Araújo , Bastos Victor Hugo do Vale , Teixeira Silmar Silva , Peres Jessica Ohrana Façanha Bastos , Aragão Jessika Ferreira
Published: October 2024

O Transtorno do Déficit de Atenção/Hiperatividade é um transtorno mental caracterizado pela presença de sintomas de desatenção e/ou hiperatividade/impulsividade que levam a prejuízos significativos na vida dos indivíduos afetados. O mesmo é tido como a condição mais comumente diagnosticada na infância e na adolescência, mas podendo persistir na vida adulta, em uma grande proporção dos casos iniciados na infância. Somado a tudo isso muito tem se visto a respeito deste tema, com predominância para as crianças e adolescentes, mais um déficit para a população adulta. Considerando esta lacuna, e em observância a baixa efetividade dos tratamentos convencionais na população adulta, e com os avanços das novas tecnologias e tendo a realidade virtual sido utilizada para uso terapêutico nas mais diversas neurodesordens esse trabalho tem como objetivo verificar os efeitos da realidade virtual em pacientes adultos com traços de TDAH. Para isso, 10 adultos com traços de TDAH, foram submetidos voluntariamente a realidade virtual por dias alternados com intervalos de 24 horas, além da aplicação do teste ETDAH-AD. Como resultado observou-se que em dias e condições alternadas apresentou-se pequenas melhoras mais nada significativo.
Agricultura urbana conhecer para promover: um despertar no Território de Identidade do Vale do Jiquiriçá/BA
Authors: Conceição Adriana Martins da Silva Bastos , Moreira Márcia Bento , Freitas Helder Ribeiro
Published: October 2024

O presente trabalho tem por objetivo analisar as concepções e percepções sobre a prática da agricultura urbana e periurbana junto a profissionais das Secretarias Municipais de Agricultura dos municípios que compõem o Território de Identidade do Vale do Jiquiriçá – BA a partir do mapeamento a de experiências no referido território. Para isso realizou-se uma pesquisa exploratória através de questionários online, etapas I e III, e pesquisa de campo na etapa II. Nos questionários foram identificadas apenas 12 experiências agricultura urbana e periurbana. Já nas visitas de campo este número saltou para 62 experiências ativas. Na etapa III os dados mostraram que falta entendimento dos profissionais sobre o conceito de Agricultura Urbana e suas potencialidades e ainda que os dispositivos legais que regulamentam essa pratica devem ser amplamente difundidos para sua implementação. Esses dados demonstram que a prática da agricultura nas cidades do território passa despercebida na dinâmica do TIVJ e essas não são contempladas nas políticas públicas.
Diretrizes para a realização do exame ultrassonográfico da vesícula biliar e ductos biliares em cães e gatos – Revisão de literatura
Authors: Gomes Claudio Luis Nina , Fonseca Luciano Santos da
Published: October 2024

O exame ultrassonográfico tem papel destacado quanto à obtenção de informações sobre os aspectos morfofisiológicos do fígado e das vias biliares em animais de companhia, sendo de grande utilidade na avaliação do sistema biliar de caninos e felinos domésticos. Esta revisão objetivou descrever sobre procedimentos norteadores para a realização do exame ultrassonográfico da vesícula biliar e ductos biliares em cães e gatos, destacando e ilustrando seus aspectos morfofisiológicos e ultrassonográficos abordados em literaturas científicas.
The Anti-Corruption Mechanisms and Measures
Authors: Tokhtamishovich Ochilov
Published: October 2024

The fight against corruption remains one of the most urgent issues of today's world. The fight against this disease covers many countries of the world. Many practical works are being done in the fight against corruption in the countries of the world. Currently, a number of programs have been adopted in different countries as part of the fight against corruption, and extensive work is being carried out on them. The article examines the experience of the countries of the world in fighting corruption.
SME Family Firms and Strategic Digital Transformation: Inverting Dualisms Related to Overconfidence and Centralization
Authors: Bouncken Ricarda , Schmitt Florian
Published: October 2024

The high uncertainties, investments, and demands related to digital transformation are especially crucial for resource constraint small and medium sized family firms. Our qualitative case study resonates with previous research, finding that such firms show low levels of strategizing and a pragmatic-incremental approach to digital transformation, often hindered by their traditionalism. In addition, we reveal that small and medium sized family firms tend to follow a reactive digital transformation. A reactivity trap appears when they operate in strongly regulated industries that demand extensive attention on such institutionalized pressures. Additionally, we draw attention to two inverting dualisms. First, strong top management centralization which is most detrimental to digital transformation as it is accompanied by low digital competence of managers. Second, manager’s overconfidence about their competitive positioning and concurrently discounting and frightening digitalization. In theorizing our findings, we provide propositions and a process model. In the realm of practical implementations, our study suggests digital maturity models for identifying the (relational) status quo of the SME’s digitalization.
El sueño del pobre y el sueño del rico
Authors: Torres Quintero Gregorio
Published: October 2024

Es un cuento de misterio. Un cuento de sueños, fantasmas, monjes, ricos hacendados y un pobre zapatero. El maestro Torres Quintero nos cuenta que todo es posible en los sueños teniendo un poco de fe. La ironía y el humor también son visibles. Una muestra más de que los pueblos y las casonas tienen en su interior muchas historias que merecen ser contadas.
Improving willingness-to-pay studies for traditional food products in developing countries: Evidence using repeated experiments
Authors:   Department of Economics, The University of Manchester, Manchester, UK/Department of Agricultural Economics, University of Ilorin, Nigeria., Animashaun Jubril , Awogbemi Kofoworola A ,   Department of Agricultural Economics, University of Ilorin, Nigeria, Karim Ramota O ,   Department of Home Economics and Food Science, University of Ilorin, Nigeri, Emediegwu Lotanna E ,   Department of Economics, Policy and International Business, Manchester Metropolitan University, Manchester, UK
Published: October 2024

Willingness-to-pay (WTP) studies for traditional food products are plausibly affected by unobserved decisions and strategic collusion between the experimenter and respondents. Similarly, WTP estimates in developing countries using a one-time survey might be inconsistent, as the acceptance of new products likely varies with exposure to product attributes. We use repeated experimentation, where subjects are randomised twice on treatments, to reduce hypothetical bias and account for dynamic convergences of consumers’ preferences. We rely on longitudinal variation in treatments, which allows subjects’ characteristics and setting to have little influence on WTP estimates. These experimental designs evaluated consumers’ preferences for cakes from high-quality cassava flour (HQCF) and wheat flour mixtures in Nigeria. When analysed separately and combined in panels, we find a time-consistent, insignificant difference in consumers’ preferences and WTP for all cake categories. Nonetheless, we find evidence of texture and moistness as favourable attributes of HQCF cakes. Intensifying agronomic research and processing techniques that enhance favourable attributes such as the texture and moistness of HQCF could improve acceptance.
Journal of Medicinal Natural Products: A New Journal with a New Perspective
Authors: Nahar Lutfun
Published: October 2024

Editorial
Journal of Medicinal Natural Products: A New Journal with a New Perspective

Lutfun Nahar 1,2

1  Centre for Natural Products Discovery, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK; L.Nahar@ljmu.ac.uk or nahar@ueb.cas.cz
2  Laboratory of Growth Regulators, Palacký University and Institute of Experimental Botany, The Czech Academy of Sciences, Šlechtitelů 27, 78371 Olomouc, Czech Republic
Received: 7 April 2024; Accepted: 20 April 2024; Published: 14 May 2024
Constructing Ethnolinguistic Identities: A Critical Examination of Language and Power Dynamics in Diasporic Communities
Authors: Nuristani Sarwar , Dadman Enayatullah , Stanikzai Sultan Mohammad
Published: October 2024

This research investigates the complex interplay between language and power in the formation of ethnolinguistic identities within diasporic communities. As globalization accelerates, diasporic groups navigate a complex landscape where traditional linguistic practices intersect with new socio-political realities. This study aims to critically examine how language functions as a tool for negotiating identity and power within these communities, emphasizing the role of language ideologies and practices in shaping social dynamics. The primary objectives are to explore how language serves as a medium for the construction and negotiation of ethnolinguistic identities and to understand the influence of power relations on these processes. Specifically, the study seeks to identify the ways in which language practices reflect and challenge power structures within diasporic contexts and how these practices contribute to the formation of collective and individual identities. This research is a multi-sited ethnographic approach,and integrates discourse analysis across several diasporic communities. Findings reveal that language serves as a strategic resource for negotiating social status and ethnic belonging. Diasporic individuals employ code-switching, language reclamation, and multilingualism to assert identity and resist assimilation pressures. The study highlights how language ideologies both reinforce and contest existing power structures, demonstrating the dynamic role of language in shaping ethnolinguistic identities amidst shifting socio-political landscapes.
Incidência de internações relacionadas a deficiência intelectual: perspectivas epidemiológicas e impactos no cuidado clínico
Authors: Chaves Francisco Neudo Rebouças , Souza Ana Aparecida Adeodato de , Lucena Gabriel Saraiva Martins , Andrade Ingrid Milena Marques de , Igarashi Ágatha Thomé , Ribeiro Tássia Peixoto , Pires Emilly Maria Borba , Oliveira Maria Paula Bianchim , Vidal Ana Lúcia Farias , Vargas Jonathan França , Medeiros Mariana Bouth de , Silva Jordam William Pereira
Published: October 2024

A deficiência intelectual é uma condição que se caracteriza por limitações significativas no funcionamento intelectual e no comportamento adaptativo, impactando habilidades conceituais, sociais e práticas. Essas limitações surgem antes dos 18 anos e podem ser causadas por fatores genéticos, complicações durante a gestação ou problemas ambientais. A deficiência intelectual afeta a capacidade de aprender, tomar decisões e interagir com o ambiente, exigindo suporte contínuo e cuidados especializados. A compreensão e a gestão dessa condição são essenciais para promover a inclusão social e a qualidade de vida, com foco em estratégias de prevenção, tratamento e apoio adaptado às necessidades individuais. O objetivo desse trabalho foi descrever um panorama epidemiológico das internações causadas por deficiência intelectual no Brasil, no período de 2019 a 2023. Este é um estudo de séries temporais, que usou dados do Sistema de Informações Hospitalares (SIH) do DATASUS. Entre 2019 e 2023, o Brasil registrou uma redução de 16% nas internações por deficiência intelectual. O ano de 2019 teve o maior número de internações (22,8%), seguido por 2021 (19,8%). Os últimos dois anos representaram 38,4% do total de internações. A maioria das hospitalizações foi de caráter urgente (74%), enquanto 26% foram eletivas. A análise revelou predominância de homens brancos entre os internados e maior incidência na faixa etária de 20 a 29 anos. Essas informações destacam a necessidade de melhorias contínuas nos cuidados preventivos e na gestão das condições associadas à deficiência intelectual.
Características dos exames de colpocitologia oncótica em distritos de saúde de uma região pré-amazônica e sua associação com a faixa etária: uma análise com distribuição espacial
Authors: Lobato Fernando Luís Bacelar de Carvalho , Caminha Hugo Dias , Lobato Silvana Jozie Assunção Braga Bacelar , Gambassi Bruno Bavaresco , Martins Rafiza Felix Marão , Silva Maria Raimunda Chagas , Falcai Ângela , Firmo Wellyson da Cunha Araújo
Published: October 2024

Esse estudo visou caracterizar a distribuição espacial dos exames de colpocitologia oncótica e sua associação com a faixa etária em distritos de saúde do município de São Luís, Maranhão, Brasil. Para tal, realizou um estudo documental, transversal e retrospectivo, analisando 14.305 exames de citologia oncótica realizados no ano de 2022 por um laboratório de referência, obtidos de 9 distritos de saúde e um hospital público. As variáveis estudadas foram: faixa etária, localidade de realização do exame, características da amostra (tipo de epitélio, adequalibilidade e conclusão), atipias e lesões encontradas e achados microbiológicos. Os dados foram dispostos em frequência absoluta e relativa.  A diferença significativa foi obtida com o p<0,05 entre os grupos utilizando o teste de Qui-quadrado para as variaveis categóricas. A faixa etária das mulheres de 40 a 49 anos (23,36%), foram as que mais realizaram os exames. As pacientes oriundas do distrito de saúde Itaqui-Bacanga (22,59%), foram as que mais realizaram os exames.  O epitélio mais observado nas amostras foi do tipo escamoso (44,73%), sendo essas amostras satisfatórias (99,63%) e sem alterações não neoplásicas (94,53%). As atipias e/ou lesões observadas por epitélios, 20,55% das mulheres apresentaram células escamosas atípicas que não descarta alto grau (ASC-H). A ocorrência de Gardnerella/Mobiluncus foi de 45,22% nos exames. Houve associação estatisticamente significativa da faixa etária como as variáveis atipias em células escamosas, lesões em células escamosas e microbiologia com p valor de <0,001. Medidas direcionadas para o rastreamento mais eficazes de grupos prioritários, promoção da vacinação contra o papilomavírus humano e acesso a diagnósticos e tratamentos oportunos, são necessários, visto principalmente que o cancer de colo uterino é uma realidade.
Towards a Conversational Ethics of Large Language Models
Authors: Kempt Hendrik , Lavie Alon , Nagel Saskia K.
Published: October 2024

Large Language Models are one of the most prominent examples of current uses of AI, and one of the most urgently pursued normative tasks is to make them and their interactive user-interfaces—open-domain chatbots—safe. However, in this paper, we elaborate first on why such a limited view on the permissibility and desirability of their utterances falls conceptually flat, is philosophically insufficient, and leads to severe technological limits. We then propose a positive normative concept, appropriateness, that can provide the required orientation for determining what chatbots may or may not say, and distinguish between technical-discursive, social, and moral appropriateness. Lastly, we explore the requirements for social and conversational contexts to fulfill appropriateness-requirements, and find that positionality is a key element for their position in discourse.
Automated Influence and Value Collapse
Authors: White Dylan J.
Published: October 2024

Automated influence is one of the most pervasive applications of artificial intelligence in our day-to-day lives, yet a thoroughgoing account of its associated individual and societal harms is lacking. By far the most widespread, compelling, and intuitive account of the harms associated with automated influence follows what I call the control argument. This argument suggests that users are persuaded, manipulated, and influenced by automated influence in a way that they have little or no control over. Based on evidence about the effectiveness of targeted advertising as well as empirical results about the nature of attentional control, I provide reasons to reject this argument. In turn, I use C. Thi Nguyen's theory of value collapse to develop a new account of the harmfulness of automated influence.
Analisis Pengukuran Tingkat Kesehatan Bank Menggunakan Metode Camels dan RGEC pada Bank Konvesional yang Terdaftar di BEI Periode Tahun 2019-2023
Authors: Aurellia Bunga Wana Citra
Published: October 2024

A bank is an institution that collects public funds in the form of savings. This study aims to analyze the health levels of banks listed on the Indonesia Stock Exchange (BEI) from 2019 to 2023 using the Camels and Rgec methods. This research utilized a quantitative descriptive approach. The research population consisted of state-owned banks listed on the BEI, with a sample size of 4 companies: BNI, BRI, BTN, and Mandiri. Data collection techniques involved documentary methods using secondary data, specifically the financial reports of state-owned banks available on the BEI or respective bank websites. The research findings indicate that for Bank BNI, the Camels score indicates a healthy status with a score of (90.84), while the Rgec score indicates a very healthy status with a score of (90.66). For Bank BRI, the Camels score suggests a fairly healthy status with a score of (71.65), and the Rgec score indicates a very healthy status with a score of (86.67). Bank BTN shows a less healthy status with a Camels score of (60.89), but a healthy status with an Rgec score of (76.67). Bank Mandiri exhibits a less healthy status with a Camels score of (62.02), while the Rgec score indicates a very healthy status with a score of (87.33).
Pengaruh Promosi dan Harga terhadap Penjualan pada CV Bandar Sinergi Utama Kota Tangerang
Authors: Ridwan Maulana  , Herayati Herayati  , Vicky Windasari
Published: October 2024

The purpose of this research is to determine promotions and prices for sales at CV Bandar Sinergi Utama, both partially and simultaneously. This research is associative with a quantitative approach. Sampling was taken using the Slovin technique. The sample used in this research was 38 respondents. Data collection techniques used questionnaires, data analysis techniques using validity, reliability, hypothesis testing, t tests and f tests with SPSS version 21 software. The research results showed that: (1) Promotion has an effect on sales with a coefficient of determination value of 0.594 which has a significant effect on sales with the result tcount > ttable or (7.250 > 2.030) with a significance value<0.050 or (0.00 < 0.05). (2) There is an influence of price on sales with a coefficient of determination of 0.658 with the result tcount > ttable or ((8.319 >2.030) with a significance value <0.05 or (0.00 <0.05). (3) promotion and price has an effect on sales with the regression equation Y = -0.055 + 0.250 X1 + 0.522 < 0.05) then in this study Ha is acceptable.
PENERAPAN PEMBELAJARAN Al-QUR’AN UNTUK MEMPERBAIKI BACAAN AL-QUR’AN PESERTA DIDIK (STUDI PADA TAMAN PENDIDIKAN AL-QUR’AN NURUL HUDA KARTOPURAN KECAMATAN SERENGAN SURAKARTA TAHUN AJARAN 2022/2023)
Authors: Fadhilah Nurul , Rochmawan Alfian Eko , Sulistyowati S
Published: October 2024

TPQ is a non-formal Al-Qur'an education park where there are various lessons about the Al-Quran and how to improve reading and tahsin so that TPQ students are introduced to what the Al-Qur'an is and also about learning Islamic religious education. That way students will know how good morals are according to the teachings of Rasulullah SAW. This TPQ study aims to find out the application of Al-Qur'an learning, and to find out the factors that support and hinder the application of quality Al-Qur'an learning at TPQ Nurul Huda Kartopuran, Serengan District, Surakarta, Academic Year 2022/2023. This study uses qualitative methods and uses data collection tools in the form of observation, interview methods, and documentation. Then from the results obtained, the researcher will describe briefly and then the researcher will conclude so that the results are appropriate. Based on the results of the research that has been obtained, the application of learning the Koran at TPQ Nurul Huda Kartopuran, Serengan District, Surakarta, for the 2022/2023 academic year is quite good, because there are competent teachers who are educated first so that learning can develop. In addition, the application of learning is also assisted by the existence of guidelines and several methods that have been used. The factors that support and hinder the application of Al-Qur’an learning at TPQ Nurul Huda Kartopuran, Serengan District, Surakarta, for the 2022/2023 Academic Year are, collaboration between TPQ administrators and parents, facilities and infrastructure, donors, and competent teachers.
IMPLEMENTASI PEMBELAJARAN AKIDAH AKHLAK DALAM MEMBENTUK KARAKTER SISWA KELAS VIII DI MTS NEGERI 2 SUKOHARJO
Authors: Hayati Nadia Fadila , Hidayat M. Yunan , Abdullah Mu’in
Published: October 2024

Learning moral aqidah is one of the curricula taught at secondary education level which has a big influence on students' behavior, both in school life and outside of school. This research aims to find out how moral learning is implemented in shaping the character of Class VIII  students at MTs Negeri 2 Sukoharjo. The approach in this research is a qualitative approach, using descriptive case study research. This research was conducted at MTs Negeri 2 Sukoharjo using data collection techniques in the form of observation and interviews. Aqidah Akhlak learning is used as a media for the process of forming polite character in students. This is supported by the role of Aqidah Akhlak teachers in directing and cultivating good moral character so that in the future students become good individuals in society. The culture of shaking hands before entering class at MTs Negeri 2 Sukoharjo is an inspiration for the polite character of students who need to be emulated in the millennial era.
ACUAN DAN RUANG LINGKUP EVALUASI PADA MATA PELAJARAN FIQH DI SMP ISLAM AMANAH UMMAH MOJOLABAN SUKOHARJO
Authors: Pangesti Juni Swan , Ridho Ahmad Rosyid , Suparman Muh. Fatahillah
Published: October 2024

This research aims to investigate the references and scope of evaluation in the Fiqh subject at SMP Islam Amanah Ummah Mojolaban Sukoharjo. With a deep focus, this study employs a qualitative approach involving observation, interviews, and document analysis. The main objectives are to explore the role of Islamic religious teachers in enhancing students' learning motivation and to assess the success of integrating religious values into the evaluation. The qualitative method is chosen to gain an in-depth understanding of the phenomena, with data collection through direct observation and interaction with teachers and students. The research findings indicate that the evaluation in the Fiqh subject at SMP Islam Amanah Ummah Mojolaban Sukoharjo has successfully integrated religious values. However, there is a need to enhance the variety of evaluation methods, provide additional training for teachers, and refine annual evaluation reports. Concrete recommendations are presented to improve the effectiveness of educational evaluation in the Fiqh subject.
TUJUAN, FUNGSI DAN PRINSIP EVALUASI PEMBELAJARAN PENDIDIKAN AGAMA ISLAM DI PONDOK PESANTREN SURYANI SURAKARTA
Authors: A’yuni Qurrotul , Pangesti Juni Swan , Suparman Muh. Fatahillah
Published: October 2024

This research aims to evaluate the implementation of Islamic Education (PAI) learning at Pondok Pesantren Suryani Surakarta, focusing on the objectives, functions, and principles of the evaluation employed. The research adopts a qualitative method, utilizing data collection through observation, interviews, and document analysis involving teachers and students at the pesantren. The evaluation is intended to identify strengths and weaknesses in the implementation of PAI learning and provide recommendations for improvement and development. The evaluation results indicate that the strengths of PAI learning at Pondok Pesantren Suryani Surakarta include the extensive educational backgrounds and experiences of Islamic teachers, their ability to deliver material effectively, and the creation of a conducive learning environment. The use of the halaqah teaching method also allows for active student interaction in understanding Islamic teachings. However, the evaluation also reveals weaknesses, such as limitations in technological resources and the need to accommodate student diversity. Recommendations for improvement include enhancing access to and the use of technology in learning, adopting more inclusive teaching strategies, and developing teacher competencies. Thus, Pondok Pesantren Suryani Surakarta can continue to enhance the quality of Islamic education, meeting the urgency of shaping the character, morals, and religious values of the younger generation, and making a positive contribution to society.
MANAJEMEN PEMBELAJARAN FIQIH MAWARIS DALAM KITAB MABAHITS FII ILMI MAWARITS UNTUK MEMBENTUK KARAKTER ADIL DI MAHAD ALY BAHASA ARAB DAN PENDIDIKAN ISLAM SURAKARTA
Authors: Abasir Muttorik Alil , Daliman D , Hidayat Febryan
Published: October 2024

Learning management in science is a series of managemenent processes and leadership efforrts form teachers in planning, implementing, assessing, or evaluating a lesson in order to achieve predetermined goals. The focus of the research is to find out how the management learning the science of roses in the book Mabahits fii ilmi mawarits is to form a fair character for student at Mahad Aly Arabic and Islamic Education in Surakarta. This research uses a descriptive-qualitative approach. Collecting data using observation techniques, interviews, an documentation. The data analysis technique uses descriptive-qualitative with an interactive model by Miles Huberman and Saldana with step: 1) Condersing data 2) Presentation of data 3) Drawing conclusions. The data validity method uses source triangulation and technique triangulation. Learning planning can be carried out by all teachers, while implementation is generally carried out by full-fledged science teachers, and evaluation is also carried out in various ways to obtain maximum result.
ISLAMISME, MODERASI BERAGAMA, DAN SOLO GENEOLOGI PEMAHAMAN MODERASI BERAGAMA KELOMPOK ISLAM DI SOLO
Authors: Warsito W , Abdillah Anisa , Fadhilah Lulu' , Abdillah Anaqoh
Published: October 2024

The diversity of beliefs, religions and cultures of the Indonesian nation is an inevitability that often causes friction between residents. Some groups force their beliefs on other groups and even commit violence in the name of religion to achieve this goal. This is what drives the government through the Ministry of Religion to promote Religious Moderation so that Indonesian people do not get caught up in religious fanaticism. This study is a library research that uses books and journals as the main documents with the background of the city of Solo which is known as one of the pockets of the Islamic movement. The study found that the extreme understanding of Islamic groups is based on their belief that Indonesia is not an Islamic country that must be Islamized and based on their understanding of wala' wal bara' which forms an understanding to be hostile to infidels and reject their leadership. Therefore, strengthening literacy and dialogue are the means that must be carried out to change this extreme understanding.
FASTING BLOOD SUGAR (FBS) IN THE FIRST TRIMESTER: PREDICTIVE VALUE FOR GESTATIONAL DIABETES MELLITUS AND IMPACT ON PREGNANCY-RELATED OUTCOMES
Authors: MARYAM B , YASMEEN H , MANAF A , ASIF M , ALAM F , ALAM S , SOHAIL A , HUSSAIN Z , KHAN M , MUSTAFA A , AHMED I
Published: October 2024

Gestational diabetes mellitus (GDM) is a significant health concern in pregnancy, affecting maternal and neonatal outcomes. Early detection of GDM through fasting blood glucose (FBS) screening may help in timely management to prevent complications. Objective: To determine the fasting blood glucose threshold that accurately predicts the onset of gestational diabetes mellitus (GDM) and its impact on pregnancy outcomes. Methods: A prospective cohort study was conducted at the Obstetrics and Gynecology Department of Jinnah Postgraduate Medical Centre (JPMC), Karachi, from August 2023 to May 2024, involving 405 pregnant women selected through systematic random sampling. Inclusion criteria included singleton pregnancies, excluding women with pregestational diabetes or baseline fasting glucose levels of 126 mg/dL or higher. Baseline data on age, BMI, gestational age, and family history of diabetes were collected, and FBS levels were measured at the initial visit. Oral Glucose Tolerance Tests (OGTT) were conducted between 24 to 28 weeks of gestation to diagnose GDM. Maternal and fetal outcomes were monitored until delivery. Statistical analyses, including logistic regression and ROC curve analysis, were performed using IBM SPSS version 20. Results: Among the 405 participants, with a mean age of 28 ±6.49 years, the mean fasting blood sugar (FBS) was 89.5 mg/dL (±12.3). Impaired FBS (≥92 mg/dL) was noted in 24.70% of participants, and 18.27% were diagnosed with GDM following OGTT. A fasting glucose level of 127.4 mg/dL (±22.1) was observed among women diagnosed with GDM. Logistic regression showed a significant association between FBS ≥92 mg/dL and GDM risk (OR 1.08, CI 1.02-1.14, p=0.011). ROC analysis revealed an FBS cutoff of 92 mg/dL with 73% sensitivity and 68% specificity for predicting GDM. Gestational hypertension was observed in 8.64% of participants, and preeclampsia in 6.67%. Vaginal deliveries occurred in 72.1% of cases, while 27.9% required cesarean sections. Neonatal outcomes showed an 11% macrosomia rate, with 12% requiring NICU admission. Conclusion: Fasting blood glucose levels ≥92 mg/dL in early pregnancy are strongly predictive of gestational diabetes mellitus (GDM). Early FBS screening allows for timely intervention, potentially improving maternal and neonatal outcomes. This study underscores the importance of incorporating FBS screening in routine antenatal care for better pregnancy management.
Individualized medication card assists the elderly with medication understanding and adherence
Authors: Bumpus Penelope Joy , Rogers Jennifer L. , Rust Michael Shane
Published: October 2024

Objective: In the outpatient setting, polypharmacy and poor communication among providers has left a gap in drug education involving the elderly population.  Linking all of these providers with an accurate medication regimen may be the answer.  Nurses can play a pivotal role in drug-related problems in the elderly population. The aim of this study is to use a liaison nurse to help educate the elderly population on the importance of adherence and understanding their medications by using an individualized medication card.Methods: This study used a descriptive study design. A convenience sample (n = 16) of patients, who were sixty-five years of age or older and were taking five prescription medications daily was employed. After collecting patient demographic information, a counseling session was performed with the patient on their medications using an individualized medication card. Data was then collected via two follow-up phone calls at two and four weeks after initial counseling session using a medication questionnaire and a set of five follow-up questions.Results: Sixteen participants received counseling on their medications and an individualized medication card to take home. Only thirteen participants were reached via phone call, two weeks after their initial counseling session. Of these thirteen, two had lost or forgotten their medication card. Eleven reported that the medication card had been helpful in understanding and adhering to their medications. Of the participants who kept their cards, all were satisfied with the counseling materials and methods used.Conclusions: The findings indicate that the elderly population who were taking five or more prescription medications showed benefit from counseling on their medications using an individualized medication card. Such a tool will help nurse practitioners guide elderly patients in medication education and adherence in future practice.
Technological aspects of growing commercial trout on the basis of IP «Ak Balyk»
Authors: Abilov B. I.
Published: October 2024

The materials for the preparation of the article were based on samples and observations taken at the stage of entering the IP "white fish".

Research on this topic was carried out using hydrochemical methods, production technologies and evaluation of fish products.

As a result of the study, it was found that:

1. A fish pond with an area of 1.2 hectares, an average depth of about two meters with a fresh water supply of 16 liters/ sec.

2. A basin area with a total water volume of 985.8 m3 and a water exchange rate of 46 l/sec, for commercial trout cultivation.

There are no sources of anthropogenic impact and factors negatively affecting the ecology of the environment in the fish farming area of IP "Ak Balyk".

According to hydrochemical indicators, the water on the farm meets the requirements for fish farming.
Design and implementation of a scalable IoT-based real-time environmental monitoring and alarm system: an experimental study
Authors: Ceken Celal
Published: October 2024

Digital transformation is crucial for organizations to survive, be competitive, and grow in the modern age. IoT is the key to enabling this transformation by connecting devices and optimizing processes. This paper presents the design and implementation of a generic IoT-based real-time environmental monitoring and alarm system. The platform is validated by applying it to a manufacturing plant scenario, where various sensors simulate industrial conditions. Scalable message distribution systems such as MQTT and Apache Kafka facilitate reliable data transmission. A microservice architecture is constructed for the backend services to ensure uninterrupted and high throughput services in the application domain. Instead of deploying a real WSN, traffic generation services were chosen to minimize costs, provide greater control and flexibility, and facilitate faster, scalable testing in a controlled environment. The platform also features an integrated alarm system with an event definition module, which allows users to define custom action rules. This flexible, scalable, and resilient architecture can be used across a wide range of application domains that require digital transformation. The experimental study demonstrates the platform's capabilities and great potential for broader IoT applications.
Linguistic analysis of Lovecraft’s mythological names
Authors: Starkova A. V.
Published: October 2024

This article explores the etymology and pronunciation of two of H.P. Lovecraft’s most iconic mythological deities: Cthulhu and Nyarlathotep. Through an extensive review of existing literature and comparative analysis, we uncover the linguistic roots and cultural influences that shaped these names. Lovecraft’s meticulous approach to naming his deities reflects his fascination with ancient mythologies, linguistic creativity, and contemporary figures. The findings suggest that the names Cthulhu and Nyarlathotep are deeply embedded with historical and mythological significance, enhancing the otherworldly and timeless nature of Lovecraft’s mythos. This study contributes to the broader understanding of Lovecraft’s literary genius and sets the stage for continued scholarly exploration of his cosmic horror universe.
Levels of Vision
Authors:   , Aqil Marco
Published: October 2024

A goal of cognitive neuroscience is to provide accounts of brain functions in terms of information processing. Vision has long been used as a beachhead for such approaches: information-processing principles first identified in the visual system, such as receptive fields and divisive normalization, have later been observed in a variety of other sensory and cognitive domains. Here, we formulated a visual-spatial population receptive field model based on divisive normalization, a candidate ‘canonical’ neural computation. We showed that the model unifies and outperforms existing models, and that it does so via local variations in its algorithmic parameters. Next, we hypothesised that neurotransmitter systems might provide the biological-implementational substrate underlying the model’s algorithmic modulations. We showed that model parameter estimates are related to density maps of different serotonin and GABA receptors. Finally, in order to directly probe the role of neurotransmitter systems in human visual computations, we administered psilocybin, a serotonin receptor agonist. We showed that psilocybin systematically alters normalization, and in particular the model’s parameter relevant for suppression (center-surround configurations). Our findings provide direct causal evidence of the involvement of neurotransmitter receptors in visual computations in the living human brain. In sum, this thesis brings together vision science with chemoarchitecture and neuropharmacology, providing new insights into the inner workings of the human visual system.
1960 KIBRIS CUMHURİYETİ’NİN HUKUKİ VE SİYASİ ZEMİNİ
Authors: Yurtseven Yilmaz , Adagideli Hüseyin Ömer
Published: October 2024

Kıbrıs, Doğu Akdeniz’de gerek fizikî gerek stratejik konumu itibarıyla tarih boyunca hep cazibe merkezi olmuş bir adadır. 1571’de Osmanlı Devleti adayı o dönem Akdeniz’deki en büyük askeri deniz gücüne sahip olan Venedik’in elinden almıştır. Ada, 1877-1878 Osmanlı Rus Savaşı’nın ardından gelişen olaylar sonrasında İngiltere’nin egemenliği altına girmiştir. 300 yılı aşkın Osmanlı yönetiminde kalan adanın Türk ve Rum halkları barış içinde bir arada yaşamışlardır. Ancak adanın İngiliz egemenliğine girmesiyle bu barış ortamı bozulmuş ve ada günümüze kadar süren bir istikrarsızlığa sürüklenmiştir.
1878’den bu yana Kıbrıs sorunu, halen uluslararası gündemden düşmeyen önemli bir yere sahiptir. Çözümsüzlüğü getiren önemli etkenlerden biri ilgili tarafların çok olmasıdır. Ada halkını oluşturan Türkler ve Rumlar, Türkiye, Yunanistan, İngiltere, Amerika Birleşik Devletleri ve Avrupa Birliği ile adaya yakınlıkları sebebiyle Akdeniz’in güney kesiminde yer alan ülkeler Kıbrıs Sorunu ile bağlantılı konumdadır.
II. Dünya Savaşı’nın ardından değişen dünya dengeleri çerçevesinde İngiltere’nin dünya politikası üzerindeki etkinliği azalmıştır. Bu durum İngiltere’nin Kıbrıs üzerindeki egemenliğini de sürdürülebilir olmaktan çıkarmıştır. Adada yaşayan Türk ve Rum halkları arasında şiddete varan çatışmalar, meselenin Birleşmiş Milletler’e taşınmasına yol açmıştır.
Bu makalede II. Dünya Savaşı sonrası Kıbrıs’ın uluslararası bir soruna dönüşmesi sonucunda gerek BM gerek meseleye taraf olan devletlerin Kıbrıs’ta bir statüko oluşturmak için ortaya koydukları politik ve diplomatik çabaların bir sonucu olan Kıbrıs Cumhuriyeti’ni doğuran hukuki ve siyasi gelişmeler ele alınmıştır. Çalışmada, Kıbrıs’ta iki toplumlu ve tek devletli bir yapının ortaya konabilmesi için, soruna taraf olan devletlerin Londra ve Zürih antlaşmaları ile başlattıkları hukuki süreç incelenmiştir. Sürecin sonucunda kurulan Kıbrıs Cumhuriyeti’nin yapısı, cumhuriyete esas olan anayasanın hukuki ve siyasi açmazları ve bu sürecin başarıları ve başarısızlıkları ortaya konmaya çalışılarak, Kıbrıs Cumhuriyeti’nin neden sürdürülebilir olamadığı sorusunun cevapları aranmıştır.
METALOPOLÍMEROS COM POTENCIAL APLICAÇÃO NO COMBATE AO CÂNCER
Authors: André Stephanie Cantisano , Silvino Alexandre Carneiro
Published: October 2024

Atualmente, o câncer é considerado como um problema de saúde pública mundial. Por conta disso, busca-se por novos medicamentos antitumorais que apresentem sistemas com alta citotoxidade a células cancerosas e baixos efeitos colaterais. Diversos compostos de coordenação têm sido alvo de inúmeras pesquisas com objetivo de sua aplicação como medicamentos antitumorais. No entanto, alguns desses ainda apresentam alguns efeitos colaterais. Em virtude disso, houve o desenvolvimento de uma classe de polímeros descoberta no século XX chamada de metalopolímeros. Esta classe se destaca por causa de uma combinação única de componentes orgânicos e inorgânicos em um sistema macromolecular, sendo excelentes candidatos para a administração de fármacos, pois tentam resolver algumas desvantagens dos medicamentos convencionais como a alta toxicidade e baixa especificidade a partir de um sistema de liberação de fármacos que pode liberar o medicamento dentro das células cancerosas.
PAID PUBLICATION IN THE HAC JOURNAL: A REAL PRACTICE OR A SCOURGE OF MODERN SOCIETY?
Authors: K.I. Lukina
Published: October 2024

Introduction: The article is devoted to a controversial issue regarding the ethical side of the paid publication of a scientific article in journals included in the list of the Higher Attestation Commission. It is shown that the popularity of paid publications of the Higher Attestation Commission is due to an increase in the number of mandatory publications for all categories of scientists and researchers, which contributes to the active development of commercial publications publishing scientific articles on a paid basis. The ethical problem lies in the fact that publication fees can lead to a situation where the importance of research is determined not by the quality of a scientific article, but by the financial capabilities of the authors. Methods: The article uses methods of analysis, comparison, generalization and scientific understanding. Results: As a result, it was concluded that the fee for publication in the journals of the Higher Attestation Commission is becoming more commonplace than an unnatural phenomenon, since the requirement for mandatory free publications of the Higher Attestation Commission for such a category of students as graduate students was abolished back in 2013. Consequently, authors have a free choice as to whether to publish on a commercial or non–commercial basis. However, since the requirements for articles from non-profit publications are quite high, in some cases it is not possible to publish the required number of articles in free journals. In this regard, contacting commercial scientific publications recommended by the Higher Attestation Commission is justified. Available data: No available data. Discussion: The key criteria for deciding on the possibility of submitting a manuscript, from the author's point of view, are the requirements for the quality of research and the objectivity of peer review in the planned publication of the Higher Attestation Commission, and not the method of financing.
Association between 5-HTR1A gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder: A meta-analysis
Authors: Wu Huai-Neng , Zhu Shuang-Yue , Zhang Li-Na , Shen Bian-Hong , Xu Lian-Lian
Published: October 2024

BACKGROUND

Major depressive disorder (MDD) is a substantial global health concern, and its treatment is complicated by the variability in individual response to antidepressants.

AIM

To consolidate research and clarify the impact of genetic variation on MDD treatment outcomes.

METHODS

Adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic search across PubMed, EMBASE, Web of Science, and the Cochrane Library was conducted without date restrictions, utilizing key terms related to MDD, serotonin 1A receptor polymorphism (5-HTR1A), C-1019G polymorphism, and antidepressant response. Studies meeting inclusion criteria were thoroughly screened, and quality assessed using the Newcastle-Ottawa Scale. Statistical analyses, including χ 2 and I² values, were used to evaluate heterogeneity and fixed-effect or random-effect models were applied accordingly.

RESULTS

The initial search yielded 1216 articles, with 11 studies meeting criteria for inclusion. Analysis of various genetic models showed no significant association between the 5-HTR1A C-1019G polymorphism and antidepressant efficacy. The heterogeneity was low to moderate, and no publication bias was detected through funnel plot symmetry and Egger's and Begg's tests.

CONCLUSION

This meta-analysis does not support a significant association between the 5-HTR1A C-1019G polymorphism and the efficacy of antidepressant treatment in MDD. The findings call for further research with larger cohorts to substantiate these results and enhance the understanding of antidepressant pharmacogenetics.
Mechanism of imipenem-induced mental disorder: A meta-analysis
Authors: Zhan Zhou-Hong , Wang Jia-Liang , Wang Li-Hong , Shen Nan-Nan , Liu Xin-Wen , Yu Yan-Na , Liu Fu-Rong
Published: October 2024

BACKGROUND

Imipenem is a highly effective carbapenem antibiotic, which is widely used in the treatment of many serious bacterial infections. At the same time, it can also cause some adverse reactions, mental abnormalities are the most concerned central nervous system adverse reactions. Different patients respond differently to imipenem, and the effect of imipenem on psychiatric disorders is unclear. Therefore, meta-analysis summarizing the results of multiple previous studies can provide stronger evidence support for clinical guidelines to guide clinical rational use of imipenem to minimize risks.

AIM

To systematically review the effects of imipenem on mental-health disorders.

METHODS

Method in Cochrane Library, Web of science, PubMed, ProQuest, and China’s biomedical literature databases Wanfang, Weipu and China HowNet, the related literatures about the controlled trials of imipenem-induced mental disorders from the establishment of the database to May 2024 were searched; the included literatures were analyzed using RevMan 5.4 software; and the heterogeneity among the studies was also discussed.

RESULTS

After reviewing the literature published between 2003 and 2017, seven controlled trials with a total of 550 patients were included, with 273 and 277 patients in the control and experimental groups, respectively. The sample size of the study ranged from a minimum of 30 cases to a maximum of 61 cases. Patients in the experimental group were treated with imipenem while the control group was treated with conventional drugs. Meta-analysis showed that the incidence of mental disorders in the experimental group was higher than that in the control group (odds ratio = 3.66, 95% confidence interval: 1.11-12.11, P = 0.030); however, there was no significant difference in the incidence of adverse reactions between the two groups (odds ratio = 0.05, 95% confidence interval: 0.00 to 0.10, P = 0.060). Funnel diagrams showed that the scattered points of each study were symmetrical and distributed in an inverted funnel shape; therefore, there was no publication bias.

CONCLUSION

Imipenem can cause mental disorders in patients. However, the low quality of the included literature may have affected the final results. Therefore, it is necessary to conduct a high-quality randomized controlled study with multiple samples to further confirm the mechanism of imipenem-induced mental disorders and provide effective guidance for clinical treatment.