bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of the Stationary Phase on Resolution in the HPLC-Based Separation of Racemic Mixtures Using Vancomycin as a Chiral Selector: A Case Study with Profen Nonsteroidal Anti-Inflammatory Drugs
Authors: Gherdaoui Dehbiya , Yahoum Madiha Melha , Toumi Selma , Tahraoui Hichem , Bouazza Fatma , Lefnaoui Sonia , Zeghdaoui Abdelhamid , Amrane Abdeltif , Jaouadi Bassem , Zhang Jie
Published: December 2023

Chiral resolution is a technique of choice, making it possible to obtain asymmetric and enantiomerically pure compounds from a racemic mixture. This study investigated the behavior of vancomycin when used as a chiral additive in high-performance liquid chromatography (HPLC) to separate enantiomers of nonsteroidal anti-inflammatory drugs (NSAIDs), including ketoprofen, ibuprofen, flurbiprofen, and naproxen enantiomeric impurities. We compared two achiral stationary phases (C18 and NH2) to assess the impact of mobile phase composition and stationary phase on the vancomycin retention time in the racemic resolution of drug enantiomers. Our results demonstrated the successful enantioseparation of all drugs using vancomycin in the mobile phase (phosphate buffer 0.05 M/2-propanol, 50/50) with an NH2 column. This enhanced separation on the NH2 column resulted from the chromatography system’s efficiency and vancomycin dimers’ stereoselective interaction on the NH2 surface. This study underscores the importance of stationary phase selection in the chiral resolution of NSAIDs with vancomycin as a chiral additive. It offers valuable insights for future research and development of NSAID chiral separation methods, highlighting potential vancomycin applications in this context.
Sharp Estimates Involving a Generalized Symmetric Sălăgean q-Differential Operator for Harmonic Functions via Quantum Calculus
Authors: Al-Shbeil Isra , Khan Shahid , Tchier Fairouz , Tawfiq Ferdous M. O. , Shatarah Amani , Cătaş Adriana
Published: December 2023

In this study, we apply q-symmetric calculus operator theory and investigate a generalized symmetric Sălăgean q-differential operator for harmonic functions in an open unit disk. We consider a newly defined operator and establish new subclasses of harmonic functions in complex order. We determine the sharp results, such as the sufficient necessary coefficient bounds, the extreme of closed convex hulls, and the distortion theorems for a new family of harmonic functions. Further, we illustrate how we connect the findings of previous studies and the results of this article.
Pesticides vs. Biopesticides: From Pest Management to Toxicity and Impacts on the Environment and Human Health
Authors: Daraban Gabriel Mihăiță , Hlihor Raluca-Maria , Suteu Daniela
Published: December 2023

The environmental pollution that occurs in direct response to the widespread use of man-made/conventional pesticides results from many chemicals that require a long period of time, often decades, to degrade. The synthetic nature of pesticides also harms animals, beneficial insects, microorganisms, and plants, as well as humans. Fortunately, however, there are many natural pesticides, the so-called biopesticides, that are also effective against pests and more importantly, do not interfere with the well-being of ecosystems. Consequently, most biopesticides are safer for use around people and pets than man-made pesticides because, for example, they can be easily washed away from fruits and vegetables. The natural habitat is a rich resource with a wide selection of plants, many of which are also used to treat diseases in humans, animals, and plants. Out of concern for public health, environmental safety, and the stringent regulation of pesticide residues in agricultural commodities, the use of biopesticides is becoming increasingly important, but questions regarding potential pest resistance to these products may arise, just as is the case with conventional pesticides. Therefore, the performance and potential role of biopesticides in the management of plant pests should be prioritized due to their sustainability and importance to human and environmental welfare. In this review, we propose to highlight a scenario in which we discuss in detail the main constraints posed by the use of pesticides compared to biopesticides, starting with issues regarding their definition and continuing on to issues related to their toxicity and their impact on the environment and human health.
Association of Urinary Benzene Metabolite and the Ratio of Triglycerides to High-Density Lipoprotein Cholesterol: A Cross-Sectional Study Using the Korean National Environmental Health Survey (2018–2020)
Authors: Baek Seungju , Park Eunjung , Park Eun Young
Published: December 2023

The aim of this study was to investigate the association between benzene and toluene, and the ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C). This cross-sectional study analyzed 1928 adults using nationally representative data from the Korean National Environmental Health Survey (KoNEHS) Cycle 4 (2018–2020). Urinary trans, trans-muconic acid (t,t-MA) and benzylmercapturic acid (BMA) were measured by high-performance liquid chromatography–mass spectrometry (HPLC–MS/MS), and high-density lipoprotein cholesterol (HDL-C) and triglycerides (TGs) were analyzed by colorimetry. Survey logistic regression analysis was applied to examine the association between urinary t,t-MA and BMA and the TG/HDL-C ratio. Urinary t,t-MA is significantly associated with an elevated TG/HDL-C ratio in both men and women (for men, OR [95% (CI)]: 2nd quartile: 2.10 [1.04, 4.22]; 3rd quartile: 2.13 [0.98, 4.62]; 4th quartile: 2.39 [1.05, 5.45]; for women, OR [95% (CI)]: 2nd quartile: 1.21 [0.71, 2.06]; 3rd quartile: 1.65 [0.94, 2.90]; 4th quartile: 1.78 [1.01, 3.11]), with significant dose–response relationships (P for trend: for men, 0.029; women, 0.024). This study shows that environmental exposure to benzene is associated with the TG/HDL-C ratio in the Korean general population. This suggests that more stringent environmental health policies are needed to reduce benzene exposure.
Parental Vaccine Literacy: Attitudes towards the COVID-19 Vaccines and Intention to Vaccinate Their Children Aged 5–11 Years against COVID-19 in Thailand
Authors: Maneesriwongul Wantana , Deesamer Suhong , Butsing Nipaporn
Published: December 2023

Background: High rates of population immunity are needed to control the COVID-19 pandemic. This study aimed to assess parents’ intention to have their children, aged 5–11 years, vaccinated against COVID-19 and its influencing factors in Thailand. Methods: A cross-sectional online survey was conducted before the nationwide COVID-19 vaccine rollout for children aged 5–11 years in Thailand. A sample of 542 parents with children in this age group was recruited online. Results: In total, 58.8% of parents intended to vaccinate their child against COVID-19. Logistic regression analysis revealed that influencing factors include child age, parents’ education, interactive/critical vaccine literacy, attitudes that the COVID-19 vaccine is safe and effective for children, that the vaccine can reduce the severity of COVID-19 in children, that there were other ways to prevent children from contracting COVID-19 superior to vaccination, and that COVID-19 vaccination in children can be fatal. The main reasons for having an intention to vaccinate their children included to reduce the severity of symptoms if infected with COVID-19 and to protect them from contracting COVID-19 when they go to school. Conclusions: Our study provides evidence regarding factors influencing parents’ intention to vaccinate their children. The findings can be used to design future interventions to promote COVID-19 vaccine uptake in children.
Assessment of Immune Responses to a Trivalent Pichinde Virus-Vectored Vaccine Expressing Hemagglutinin Genes from Three Co-Circulating Influenza A Virus Subtypes in Pigs
Authors: Kumari Sushmita , Chaudhari Jayeshbhai , Huang Qinfeng , Gauger Phillip , De Almeida Marcelo Nunes , Ly Hinh , Liang Yuying , Vu Hiep L. X.
Published: December 2023

Pichinde virus (PICV) can infect several animal species and has been developed as a safe and effective vaccine vector. Our previous study showed that pigs vaccinated with a recombinant PICV-vectored vaccine expressing the hemagglutinin (HA) gene of an H3N2 influenza A virus of swine (IAV-S) developed virus-neutralizing antibodies and were protected against infection by the homologous H3N2 strain. The objective of the current study was to evaluate the immunogenicity and protective efficacy of a trivalent PICV-vectored vaccine expressing HA antigens from the three co-circulating IAV-S subtypes: H1N1, H1N2, and H3N2. Pigs immunized with the trivalent PICV vaccine developed virus-neutralizing (VN) and hemagglutination inhibition (HI) antibodies against all three matching IAV-S. Following challenge infection with the H1N1 strain, five of the six pigs vaccinated with the trivalent vaccine had no evidence of IAV-S RNA genomes in nasal swabs and bronchoalveolar lavage fluid, while all non-vaccinated control pigs showed high number of copies of IAV-S genomic RNA in these two types of samples. Overall, our results demonstrate that the trivalent PICV-vectored vaccine elicits antibody responses against the three targeted IAV-S strains and provides protection against homologous virus challenges in pigs. Therefore, PICV exhibits the potential to be explored as a viral vector for delivering multiple vaccine antigens in swine.
Climate, Water, Soil
Authors: Tzanakakis Vasileios A. , Angelakis Andreas N.
Published: December 2023

“Climate” is a complex concept [...]
Profiling of Antibiotic Residues in Soil and Vegetables Irrigated Using Pharmaceutical-Contaminated Water in the Delhi Stretch of the Yamuna River, India
Authors: Akhter Suriyah , Bhat Mohd Aadil , Hashem Abeer , Abd_Allah Elsayed Fathi , Ahmed Sirajuddin , Siddiqi Weqar Ahmad , Kulsoom Isma , Un Nisa Fahim
Published: December 2023

The movement of emerging pollutants, particularly antibiotics, from surface water to crops through the process of plant uptake poses a significant public concern related to the agricultural utilization of untreated water and biosolids. It is essential to consider the potential risk of inadvertent human exposure and the accumulation of drug residues in fresh food crops, particularly in the case of various green vegetables. Nowadays, environmental research is mainly focusing on the bioaccumulation and threat posed by pharmaceutical residues, especially antibiotics and personal care products in the soil–plant ecosystem. In the present study, the concentration of pharmaceuticals in soil samples collected from agricultural fields irrigated with Yamuna water were evaluated using suitable extraction and sophisticated instrumentation techniques. Out of the five sampling locations, the highest concentration of ofloxacin was reported at Site-V (0.265 µg/mg) during the premonsoon period and the lowest concentration (0.014 µg/mg) during the postmonsoon at Site-II, in terms of the average concentration; this could be due to the combined effect of anthropogenic activities, surface water runoff, and the combined load of drains in the vicinity. For the quantification of the selected antibiotics in a green leafy vegetable (Spinach oleracea), the concentration of ofloxacin was found to be the highest at Okhla barrage Site-V (5.586 µg/mg) during the premonsoon period, with the lowest concentration observed at Site-I, from 1.382 µg/mg to 1.698 µg/mg, during the postmonsoon period. The higher concentration of ofloxacin in crops is because of its susceptibility to being absorbed at the soil’s surface. Plant absorption of antibiotics is influenced primarily by the biological characteristics of the plant, encompassing factors like the lipid and carbohydrate composition of the plant roots. Additionally, the physiochemical properties of the drugs, including molecular size, Kow, and pKa, play a significant role in this process. The antibiotics showed greater variation in their concentration during the premonsoon than in the postmonsoon period, which may be because of precipitation, dilution, and the leaching effect of the soil. For all three of the drugs studied, the concentrations followed the order of ofloxacin > amoxicillin > erythromycin. Thus, the effective management of contaminated soils and vegetables must consider continuous monitoring and risk assessment of high-priority antibiotics to prevent negative effects on the natural environment and human health.
Features of the course of idiopathic fibrosing alveolitis
Authors:   Regional Clinical Hospital, Khabarovsk, Gulyabin K. R.
Published: December 2023

Idiopathic pulmonary fibrosis (IPF) is a special form of chronic progressive fibrosing interstitial pneumonia of unknown etiology; it occurs predominantly in elderly people, affects only the lungs, and is associated with the histological and/or radiological pattern of common interstitial pneumonia. The frequency of this pathology has been increasing in recent years. A timely diagnosis and treatment can slow down the progression of the disease and prevent the need for lung transplantation.
Producing a High Level Harmonic Acoustic Pressure Field with Harmonic Acoustic Pneumatic Source (HAPS): Experimental Validation of the Harmonic Distortion Reduction
Authors: Grandjean Pierre , Micheau Philippe , Lajoie Pierre-Olivier
Published: December 2023

Applications such as active control of fane noise, require high Sound Pressure Levels (SPL). Pneumatic acoustic sources are usually used for that purpose (e.g. the WAS 3000 and the Mark VI and VII). The harmonic acoustic pneumatic sources (HAPS) - which use the chopping of an airflow
to generate an acoustic pressure field - are being studied for applications requiring high-level harmonic acoustic pressure fields. A recent study has shown that the amplitude, phase, and frequency generated by HAPS are accurately controllable, and can reach 120 dBSPL. However, higher harmonics
are also generated at high SPL and this could be detrimental to the intended applications (e.g. active control of tonal noise). An experimental campaign dedicated to understanding the harmonic distortion of HAPS has been conducted on a single HAPS in a semi-anechoic chamber. Measurements with
quarter-wave tube at the output of the HAPS were also carried out to reduce this distortion. Levels of 120 to 130 dBSPL for the fundamental were reached, with a difference of 10 dB between the fundamental and the second harmonic (H1/H2 distorsion). Adding a quarter-wave tube increased the
acoustic pressure level from 4 to 6 dBSPL, and the H1/H2 distorsion from 2 to 8 dBSPL.
Aeroacoustic simulation of transient vortex dynamics inside double-degree-of-freedom orifice-cavity structure subjected to high-intensity acoustic waves
Authors: Qiang Xu , Wang Peng , Liu Yingzheng
Published: December 2023

As a noise reduction device commonly used for aero-engines at present, the double-degree-of-freedom acoustic liner has the advantage of broadband noise elimination, which is related to the energy transformation during the process of vortex generation and shedding from its dual orifice-cavity
unit when subjected to high-intensity acoustic waves. Based on the compressible linear Navier-Stokes equations with the influence of nonlinear thermo-viscous acoustics, this study simulated the three-dimensional acoustic-vortex coupling field of dual orifice-cavity structures with different
orifices' distances under high-intensity acoustic waves with different frequencies. The first and second resonance frequencies of the structures were found by the transmission loss coefficient. Then, through the vortex dynamics analysis, the interference behavior of the vortex shedding with
fusion and shifting was observed under the first resonance frequency when the orifices' distance was close. By establishing an energy transfer model, it was found that the energy transfer was concentrated at the upper orifice under the second resonance frequency, and the interference effect
increased the vortex kinetic energy and viscous dissipation energy here under the first resonance frequency. The relevant research results provide a theoretical basis for the structural optimization of aerodynamic noise control devices of modern aircraft.
Mass-air-mass resonance for multiple leaf partition using perforated plate
Authors: Sugie Satoshi , Suzuki Hajime , Nitta Ryuma
Published: December 2023

In an exchange counter, a taxi cabin, and so on, there is a partition between the user and the staff to secure safety. In contrast, the partition prevents speech communication between them. Thus, it is necessary to decline the sound insulation performance of the partition for their
comfortable communication. Therefore, we have proposed producing mass-air-mass resonances by applying multiple leaf partitions to decrease the performance. The partition needs to be comprised of very thin sheets and very thin air layers to cause resonances in the frequency range of approximately
500 to 2000 Hz, which is included in voice frequency. In this study, we have realized the sound insulation decline using perforated plates instead of very thin sheets. The formulae of the resonance frequencies were derived for triple or quadruple leaf partitions when using perforated plates
as partition components. Moreover, we have verified experimentally that the resonances can occur in the frequencies calculated from the formulae.
The sound environment as moderator of taste perception in fruit juice drinking experience
Authors: Istiani Noor Fajrina Farah , Masullo Massimiliano , Ruggiero Gennaro
Published: December 2023

One of the most multisensory experiences in our daily life is eating and drinking. Modifying external sensory properties (such as auditory stimuli) has been proposed as a promising framework for modulating taste perception. To this aim, it is relevant exploring the characteristic of
the sound environment where people usually consume the juice that can moderate the taste perception in drinking fruit juice. This research conducted the juice tasting experiment focusing on individuals' flavour perception while listening to 7 sound environments in a controlled multisensory
laboratory (Sens i-lab). The soundtracks were examined using several psychoacoustics parameters. such as, sound pressure level, loudness, Sharpness, Roughness, fluctuation, tonality, and Prominence were analysed. Correlation analysis reveal several patterns between the average taste rating
of the orange juice and the psychometrics of 7 environmental sounds: for example. Sweet flavour of orange juice was negatively correlated with sound level, Roughness, and sound Prominence. Vice versa, sour flavour was positively correlated with the sound level, Roughness, and the average sound
fluctuation. Further, the freshness of juice has negative correlation with sound Roughness and the juice thickness rating was negatively correlated with the average Sharpness of sound environment.
Performance of floor mats for heavy-weight impact noise reduction in a 210 mm-thick bare slab apartment houses
Authors: Yeon Jun-Oh , Moon Soon-Seong , Kim Yong-Hee
Published: December 2023

This study aims to understand the noise reduction performance of floor mats used to cover living room areas to reduce impact noise from children's jumping or walking. Several types of floor mat products, chosen based on their material and thickness, were selected from the market. The
thickness of the mats ranged from 20 mm to 40 mm. The floor impact noise characteristics of a 210- mm thick bare slab in an actual apartment house were measured before and after the installation of the floor mat. The results showed that the highest noise reduction performance of up to 5 dB
was observed when using a heavy-weight impact source with a bang machine. However, the highest noise reduction performance of up to 8 dB was observed when using a rubber ball as the heavy-weight impact source. The impact of a rubber ball dropped from a height of 40 cm, which simulates frequent
living noise, resulted in a maximum reduction of up to 12 dB. In addition, the study discussed standardized methods for rating the heavy-weight impact noise performance of floor mats based on the measurement results.
The Zwicker's psychoacoustic annoyance models for noise-induced discomfort in the electric vehicle cabin
Authors: Miao Zhenjing , Huang Yu , Yan Li , Jiang Weikang
Published: December 2023

Acoustic comfort has become an essential feature with the rapid development of the electric vehicle (EV) industry. As a representative nonlinear model, Zwicker's psychoacoustic annoyance (PA) model and a series of modified ones are established to evaluate the acoustic comfort of different
products. However, whether these PA models apply to the noise-induced discomfort in the EV cabin remains uncertain. We investigated the psychoacoustic metrics and subjective discomfort of the EV cabin noise running at various speeds from 10-110km/h under four typical road conditions, i.e.,
asphalt, concrete, gravel, and bump. Thirty subjects rated the discomfort caused by 16 noise stimuli on the standardized 0-10 point numerical scale. The correlation and partial correlation analysis confirmed that the loudness of EV cabin noise dominated, and roughness and sharpness significantly
influenced the discomfort. We identified that the original Zwicker's PA model performed well in evaluating the discomfort caused by the EV cabin interior noise and proposed a modified Zwicker's PA model that would be appropriate. Keywords: Electric vehicle, Cabin noise, Psychoacoustic annoyance,
Noise discomfort, Sound quality
Vibration and noise analysis of a vehicle equipped with magneto rheological damper
Authors: Singh Anand Pratap , Paul Manoj , Brammajyosula Ravindra
Published: December 2023

Magneto rheological fluid, often known as MR fluid or MRF, is a type of smart fluid whose properties can be altered upon the application of magnetic field. Using an applied magnetic field, these fluids can transmit force in a controlled way. Due to its beneficial characteristics, such
as low power consumption, force controllability, and quick reaction, it leads to its various possible control-based applications in the automobile sector, such as suspensions, brakes, fluid clutches, etc. In this study, applicability of MR dampers to suppress vibration and noise of an electric
vehicle is evaluated using the phenomenological models such as Bingham and Bouc-Wen. These models are integrated into the suspension system of a quarter-car model and its performance is studied using numerical methods. These models involve non-smooth, nonlinear differential equations that
can be solved using numerical methods. Model based suspension control systems may be developed for better ride comfort using this approach. The potential of this approach for design of electric vehicles is explored.
Development of analytical model for a wheel and rail vibration associated with curve squeal noise of railways
Authors: SUEKI Takeshi , SHIMIZU Yasuhiro
Published: December 2023

In this study, an analytical model for the vibrations of both a railway wheel and rail related to curve squeal noise was developed. The model was based on lumped parameter systems from the vibration characteristics of the wheel and rail and contact forces between them. Moreover, this
model included two coupling factors between a wheel and rail, and between two vibration directions. The parameters of an actual wheel and track were applied to the model and their vibrations were estimated. The measurement of the curve squeal was also carried out at a curved section in an
actual railway test line. From these measurement results, the peak frequencies in the estimated wheel vibration when passing through a curve are well simulated. Although the model needs to be improved in terms of the vibration magnitude, it has sufficient potential to simulate the vibration
related to squeal noise.
Enhancing the Recognition of Speakers in Different Distances using Voice Features
Authors: Tsai Chia-Hung Dylan , Hu Michael , Cheng Stone
Published: December 2023

This paper proposes a method to enhance speaker recognition at varying distances by adjusting the reference voice based on voice features. Speaker recognition is the process of identifying an individual based on their voice. It involves analyzing and comparing various acoustic features
of a person's voice with the reference voice in the database. Conventional speaker recognition techniques have limitations of reduced accuracy when speakers are from varying distances. In this work, we found that high-frequency signals tend to decline faster than low-frequency ones with respect
to speaker distance. Based on this, we propose a method that utilizes support vector machines (SVM) to classify speaker distance using sound features, such as the amplitude sum of high-frequency signals and the dynamic range. Once the speaker distance is determined, the reference signal in
the database is adjusted according to the distance before being used for speaker recognition. Mel-Frequency Cepstral Coefficients (MFCC) and Dynamic Time Warping (DTW) were employed as the recognition algorithm. Experiments were conducted with speakers placed at three distances, 0.1, 1, and
2.5 meters from the microphone. The experimental results reveal that signals with the frequency of 4 kHz and above experience a faster decline in amplitude than lower ones with increasing distance. The recognition results also demonstrate a significant improvement in accuracy.
Aerodynamic performance test and flow visualization for reducing acoustic liner drag in grazing flow
Authors: Oki Junichi , Ishii Tatsuya , Oinuma Hideshi , Enomoto Shunji , Nagai Kenichiro , Kubo Gai , Ishikawa Hitoshi , Hiromitsu Nagayoshi
Published: December 2023

We aim to reduce aerodynamic drag over an acoustic liner, which comprises of a perforated plate, a honeycomb core, and a rigid backplate, for aero-engine applications through both performance testing and flow visualization. Whereas the acoustic liner can attenuate engine noise, the
structural characteristic of the liner surface causes the additional drag in grazing flow, resulting in deterioration of engine fuel efficiency. In this work, acoustic liner test pieces with various hole geometries are tested in the flow duct rig capable of generating sound wave and grazing
air flow inside the duct. The static pressure drop measurement reveals that the perforation in the grazing flow direction wound increase the drag despite the same overall perforation for all test pieces. We further conduct the flow visualization using the test rig designed for water flow to
be analogous to the air flow of the flow duct rig, and the analogy is based on Reynolds number defined with the friction velocity and the representative size of an acoustic liner. The result via particle image velocimetry represents the flow patterns causing the drag.
Investigation on measurement sound field of absorption coefficient in reverberation room by numerical simulation - Relationship between room shapes and measurement results -
Authors: Tomiku Reiji , Okamoto Noriko , Otsuru Toru , Yoshida Arata , Kinjyo Yuto , Suzuki Shoma
Published: December 2023

In this study, the relationship among the shape and volume of the reverberation room, the sound absorption coefficient of the specimen, the frequency, and the obtained measurement results of the absorption coefficient in reverberation room are investigated by time-domain finite element
method. First, finite element models are created for 11 types of reverberation rooms with different room shapes and volumes, and the models are analyzed in the case that all the boundaries are rigid walls and in the case that a measurement specimen is installed on one of the boundaries. Next,
the absorption coefficients in each reverberation room are calculated and relationships among the results of the absorption coefficients, the shape and volume of the room, the absorption coefficients of the specimen and the frequency are shown. As the results, it is shown that relationship
between absorption coefficient in reverberation room and absorption coefficient of specimen was varied by the absorption coefficient of the specimen and frequency more than room volume in heptahedral irregularly shaped reverberation room.
Multiphysical numerical analysis for acoustic metamaterials in ventilated ducts
Authors: Fusaro Gioia , D'Auria Simone , D'Orazio Dario
Published: December 2023

In recent decades, metamaterials have shown interesting properties in the acoustic, mechanical, and aerospace engineering fields. The characteristic tunability on targeted bandwidth and the freedom of design have lately extended the metamaterial application in the multiphysical domain,
for example, achieving systems that simultaneously allow noise insulation and fluid passage. Numerical methods such as FEM has been validated to test single metamaterial physics issue, and lately, mixed physics have been exploited for research and industrial purposes. However, there is still
no precise method to follow when tuning acoustic metamaterials (AMMs) with different flow conditions in a multiphysical domain. For this reason, in this study, a Multiphysical FEM is evaluated to assess the implications of different flow characteristics on acoustic performance. First, two
mono-physical models separately evaluate the fluid dynamic and acoustic problem. The two physical numerical models are then combined in the second stage, and a correlation between the two approaches (mono and multi-physical) is drawn. These preliminary results could be applied to many flow
and frequency range case studies and implemented for Mechanical and Civil Engineering applications.
Atitude médica frente à morte de seus pacientes: uma revisão integrativa
Authors: Costa Daniela Silva , Nogueira João Pedro Marcelino Bueno Câmara , Delgado Luana Lopes , Cabral Matheus Almeida , De Matos Mattheus Leandro Costa , Silva Tayane Souza , Villela Edlaine Faria de Moura , Zanuzzi Tamara Rodrigues Lima , De Oliveira Fábio Morato
Published: December 2023

Introdução: A profissão médica apresenta uma visão positivista centrada em um processo que busca de forma obstinada a cura de enfermidades, e raramente ensina o profissional médico a lidar com a perda de pacientes. Esse modelo sistêmico coloca o profissional em vulnerabilidade emocional, o que ocasiona impactos substanciais na saúde física e, sobretudo, mental. Objetivos: Estabelecer uma análise transversal acerca dos impactos da falta de preparo dos médicos para lidar com a morte de pacientes, e como essa inaptidão afeta a vida do profissional de saúde e a relação médico-paciente. Metodologia: Foi-se utilizado um método revisional e comparativo, o qual aborda, também, aspectos descritivos e analíticos, de natureza qualitativa e quantitativa. Resultados: Foram selecionadas 28 produções científicas. Obteve-se uma vasta análise pregressa acerca da relação entre a falta de habilidades socioemocionais do médico para lidar com a morte de pacientes e seus impactos psicossociais no profissional médico, observando-se desde mecanismos de autopreservação a mecanismos de autojulgamento. Conclusões: Pode-se notar a clara relação entre a falta de habilidades socioemocionais do médico para lidar com a morte de pacientes e seus impactos psicossociais no profissional médico. Evidencia-se a necessidade de implantação de metodologias de ensino e aprendizagem nas escolas médicas que ampliem e antecipem a experiência prática do estudante frente a experiência de morte.
Autocuidado e prevenção do câncer de mama entre mulheres costureiras
Authors: Pereira Claudina de Fátima Cintra , Melo Eduarda Augusto , Da Silva Milena Larissa Ferreira , Santos Ruth Stephanie Neves , Neves Cynthia Emanuella Pereira Falcão , Costa Daniella Carolina de Oliveira , De Melo Michel Gomes , Silva Maciel José dos Santos , Oliveira Diego Augusto Lopes , Melo Evellyne Augusto
Published: December 2023

Conhecer as percepções sobre o autocuidado e prevenção do câncer de mama entre mulheres costureiras. Estudo descritivo, transversal de abordagem qualitativa, com a participação de 15 mulheres selecionadas por conveniência, no mês de abril de 2021. A análise dos dados utilizou o módulo de processamento de Classificação Hierárquica Descendente (CHD). Destaca-se a importância do enfermeiro na APS com ações de prevenção do câncer de mama, com 14,81% e 22,22% o que oportuniza um maior entendimento do assunto por parte das mulheres. Bem como é sabido pela maior parte das entrevistadas com estimativa de 18,52% e 25,93% que a herança genética pode ser determinante no acometimento dessa patologia. O autocuidado e a prevenção do câncer de mama em mulheres ainda são escassas pelo fato de que existe algumas dificuldades por parte dos profissionais de saúde em fazer o rastreamento principalmente do público costureiras, a prática do autocuidado e o pouco conhecimento com relação a predisposição genética como fator de risco para desenvolvimento do câncer de mama.
Influência do pH de géis clareadores para eficácia do clareamento
Authors: Reda Amani Imad , Barbosa Isadora Drumond , Martinho Paulo Victor de Araujo
Published: December 2023

O clareamento dental é um procedimento amplamente utilizado para melhorar a estética do sorriso, mas sua eficácia e segurança dependem de vários fatores, incluindo o pH dos géis clareadores dentais. O pH desempenha um papel fundamental na ativação dos agentes clareadores, na estabilidade química dos géis e na segurança do paciente durante o tratamento. O objetivo geral deste estudo é investigar a influência do pH nos géis clareadores dentais e sua relação com a eficácia do clareamento dental. Será realizada uma revisão bibliográfica abrangente para analisar as implicações do pH na ativação dos agentes clareadores, na estabilidade dos géis e na segurança dos pacientes durante o processo de clareamento dental. A metodologia deste estudo consistirá em uma revisão bibliográfica abrangente da literatura científica disponível. Serão consultadas bases de dados acadêmicas, artigos científicos, livros e outras fontes relevantes para coletar informações sobre a influência do pH nos géis clareadores dentais. Serão examinados estudos que abordem as implicações do pH na ativação dos agentes clareadores, na estabilidade química dos géis, na eficácia do clareamento e na segurança do paciente. A análise crítica dos resultados será realizada para fornecer insights sobre como o pH afeta o clareamento dental. A influência do pH nos géis clareadores dentais é um fator crítico a ser considerado para garantir a eficácia e segurança do clareamento dental. O pH afeta a ativação dos agentes clareadores, a estabilidade dos géis e a tolerância do paciente ao tratamento. A manutenção de um pH adequado é essencial para otimizar os resultados do clareamento e minimizar os riscos de efeitos adversos. Portanto, é fundamental que os profissionais da odontologia e os pacientes estejam cientes da importância do pH no processo de clareamento dental e sigam diretrizes específicas para obter um sorriso mais branco e saudável com segurança.
Cenário epidemiológico do Sarampo no Brasil: ressurgência e pandemia de COVID-19
Authors: Silva Letícia Moreira , Da Silva Gabriella Diogo , Silva Anna Beatriz Oliveira , Mendonça Aline Geovana Burégio , De Abreu Letícia Emanuely Barbosa , Santos Maiana Ranyelle dos Reis , Da Silva Monique Lira , Medeiros Ana Leticia da Silva , Oliveira Monica da Silva , Vieira Rute Nunes , Dos Santos Gabriele Severina
Published: December 2023

O sarampo é uma doença viral, aguda, extremamente grave, transmitida de forma direta. Atualmente, essa doença tem sido um grande problema de saúde pública no país e a vacina é a sua principal forma de prevenção. Apesar do desenvolvimento e disponibilidade de uma vacina eficaz, no ano de 2019, os casos de sarampo tiveram um aumento de 300% no mundo, sendo o Brasil  apontado como um dos países com o surto mais significativo. No país o sarampo é uma doença imunoprevenível que ainda preocupa as autoridades sanitárias. A pesquisa objetivou descrever o cenário epidemiológico dos casos e cobertura vacinal por sarampo no Brasil, entre 2018 a 2021. Trata-se de um estudo epidemiológico descritivo e transversal com dados secundários do Sistema de Informação de Agravos e Notificação, Sistema de Informações do Programa Nacional de Imunizações, Sistema de Informação Hospitalar e Sistema de Informação de Mortalidade. Foram calculadas as taxas de incidência e mortalidade e apresentadas as respectivas frequências absolutas e relativas. A tabulação dos dados foi realizada por meio de planilhas eletrônicas do Microsoft Office Excel 2016. Notou-se que as regiões Norte e Sudeste apresentaram as maiores frequências dos casos notificados, assim como um elevado número de casos em jovens adultos e em crianças menores de 5 anos. Durante o período do estudo nenhuma região brasileira alcançou a meta da cobertura vacinal. Diante dos achados, faz-se necessário o fortalecimento da integração da vigilância em saúde com a atenção primária para ampliar campanhas de vacinação da tríplice viral e identificação precoce dos casos para a implementação de medidas de controle do vírus.
Eficácia dos materiais restauradores temporários utilizados no tratamento endodôntico: revisão de literatura
Authors: Lima Daniara Alves , Borges Luana de Andrade , Lopes Luana Pontes Barros , Lins Milena Carolina da Silva , Da Fonseca Tiago Silva
Published: December 2023

Apresentar uma revisão de literatura e comparar os materiais seladores temporários entre seus tipos principais e mais eficazes quanto à microinfiltração marginal, bem como suas vantagens e desvantagens na abordagem clínica. Trata-se de uma revisão de literatura utilizando as bases de dados da Pubmed Medline, Biblioteca Virtual de Saúde (BVS) e Scientific Electronic Library Online (SciELO). Para a busca inicial foram combinados os Descritores em Ciências da Saúde (DECs), isolados e cruzados: Materiais Dentários, Endodontia e Restauração Dentária Temporária onde forma incluídos os estudos publicados de 2000 a 2023, sem restrições quanto o idioma de publicação. Foram excluídas as referências duplicadas e estudos incompletos. Os materiais seladores temporários são uma barreira contra a contaminação bacteriana dos sistemas de canais radiculares de dentes que se encontram em tratamento endodôntico, ou que já concluíram o tratamento e estão na espera na restauração definitiva. Os principais materiais seladores temporários endodônticos são: obturadores pré-manipulados, os obturadores a base de ionômero de vidro, a base de óxido de zinco e eugenol e os resinosos fotoativados. Observou-se que as propriedades físicas e biológicas “ideais” dos materiais obturadores temporários ainda não foram alcançadas por nenhum fabricante estando os matérias obturadores temporários passiveis de microinfiltração coronária devendo as restaurações definitivas serem confeccionadas o mais breve possível após a terapia endodôntica, uma vez que caso ocorra um intercurso no material temporária, o canal obturado ficará exposto estando passível a recontaminação em um diminuto período.
Perfil clínico e epidemiológico dos casos de óbitos por Diabetes Mellitus em Teresina, 2013 a 2021
Authors: Mascarenhas Ana Luiza Monteiro , Lopes Natália Souza Bastos , Mesquita Gerardo Vasconcelos
Published: December 2023

O diabetes mellitus (DM) é atualmente uma importante causa de morbidade e mortalidade. O Brasil ocupa o quinto lugar no ranking mundial com 16,8 milhões de pessoas com diabetes, com perspectiva de 21,5 e 26 milhões em 2030 e 2045, respectivamente. O estudo teve como objetivo geral analisar o perfil dos óbitos por Diabetes Mellitus em Teresina-PI, no período de 2013 a 2021. Tratou-se de uma pesquisa do tipo epidemiológica, documental e quantitativa, de natureza descritiva e retrospectiva, onde o cenário de coleta de dados foi o banco de dados do DATASUS, no Sistema de Informação em Mortalidade (SIM). No período analisado, foram notificados 2.681 casos de óbitos decorrentes do Diabetes Mellitus (DM) na cidade de Teresina – PI, apresentando uma média anual de casos de 297,88 com maior expressão de casos no ano de 2019, 323 (12%), seguido do ano de 2016, com 310 (11,6%) casos. O perfil destes óbitos predominou em mulheres (52%), na faixa etária de 75 anos e mais, que corresponde a 42,15% dos casos, com destaque para aquelas que apresentaram nenhuma escolaridade (26,93%) e de 1 a 3 anos (27,04%) de estudo, e cor parda (72,40%). Foi possível identificar que 70,12% dos óbitos ocorreram em ambiente hospitalar e 26,97% no domicílio, indicando fortalecimento do sistema de referência e contrarreferência nos níveis de atenção à saúde. Portanto, a prevalência do perfil clínico e epidemiológico da mortalidade por DM na cidade de Teresina – PI, no período analisado, foi de indivíduos com idades acima de 75 anos, escolaridade menor que três anos, sexo feminino e de cor parda, sendo que os óbitos foram mais prevalentes no ambiente hospitalar. Logo, o DM é uma condição crônica passível de ser evitada. Para isso, ressalta-se o fortalecimento das ações de promoção da saúde na atenção primária pelas equipes de saúde. Destaca-se que o DM é uma doença conhecida, mas que a população apresenta dúvidas em relação a doença, principalmente a população idosa. Além disso, a maioria das pessoas com DM tem dificuldade de aderir ao tratamento para evitar as complicações da doença, justificando os altos índices de morbimortalidade.
A influência do alinhamento marginal na correção do sorriso gengival: um relato de caso
Authors: Marin Heloísa Helena Scapinelli , Piardi Rafaela , Butze Juliane Pereira
Published: December 2023

A procura por procedimentos estéticos no campo odontológico tem crescido demasiadamente nos últimos anos. Um sorriso harmônico e perfeito pode ser alçando quando forem respeitados os três pilares do sorriso: dentes, lábios e gengiva. A assimetria gengival e o sorriso gengival são uma das queixas mais rotineiras entre os pacientes que se encontram insatisfeitos com seu sorriso, podendo influir negativamente na vida social, nas relações pessoais e profissionais. Portanto, o presente trabalho teve como objetivo relatar um caso clínico de assimetria gengival nos dentes anterossuperiores associado a presença de sorriso gengival, proporcionando a correção por meio do aumento de coroa clínica com a técnica minimamente invasiva, “Flapless”. Apresenação do caso: Paciente procurou atendimento na Clínica Odontológica do Centro Universitário da Serra Gaúcha – FSG, tendo como queixa principal a grande exposição e desnível gengival ao sorrir, ocasionado insatisfação estética. O tratamento oferecido ao paciente foi a correção através do aumento de coroa clínica fazendo uso da técnica minimamente invasiva, “Flapless”. A partir do relato de caso clínico é possível concluir que por meio da técnica minimamente invasiva, “Flapless”, quando bem planejada e executada, é possível obter os resultados desejados, devolvendo harmonia e uma estética satisfatória, sem a necessidade de associação de outras modalidades de tratamento.
A importância da antissepsia na odontologia: garantindo a higiene e a segurança
Authors: dos Santos Kaue Eduardo Torquato , Sousa Karen Letícia da Silva , Silva Kenya Rayanne Barros , Santos Helen Cavalcanti , De Souza Adolfo Lopes , Dos Santos Anny Kerolayne Moreira Calvante , Dos Santos Íris Regina , Cavalcanti Tayguara Cerqueira
Published: December 2023

A busca por evidências científicas nesse cenário tem sido uma constante, com revisões sistemáticas realizadas em bases de dados como SciELO, Biblioteca Virtual em Saúde e Pubmed/Medline. A literatura científica unânime em relação à eficácia das técnicas de antissepsia e assepsia reforça a importância dessas medidas na prevenção de infecções e na garantia de um ambiente seguro para procedimentos médicos e odontológicos. Portanto, é imperativo que os cirurgiões-dentistas e profissionais de saúde em geral sigam rigorosamente os protocolos de assepsia e antissepsia. Essa prática não só protege os profissionais de possíveis contaminações, mas também demonstra um compromisso com a saúde e a segurança dos pacientes, assegurando a qualidade dos cuidados prestados
Extração e instalação de implante dentário imediato
Authors: Freitas Hérica Meilyne de Araújo , De Souza Anna Beatriz Figueiredo , Nascimento Marina da Silva , Santos Vittoria Palmira de Souza , De Sá Juliana Lopes
Published: December 2023

Objetivo: Descrever sobre implantes dentários imediatos, além de vantagens e desvantagens e suas aplicações práticas. Métodos: O estudo tratou-se de uma revisão de  integrative de literatura, com artigos selecionados no período de 2017 a 2023, utilizando-se as bases de dados BVS PUBMED e LILACS. Revisão Bibliográfica: Os implantes dentários posicionados no mesmo momento da extração dentária, dão origem a benefícios relacionados a osseointegração, apresenta vantagens de diminuir alguns meses de espera para a cicatrização completa do alvéolo, concebível permanência da altura e largura do osso alveolar, restauração dos tecidos moles, atenuação dos procedimentos cirúrgicos e resultados estéticos imediatos pela utilização de restaurações provisórias. Destacou- se também que a reabilitação oral com implantes dentários é acompanhada de uma exigência estética, sendo obtida através de fatores essenciais como a avaliação detalhada do local pré-operatório, técnica cirúrgica atraumática e um delineamento eficaz do processo para uma adequada instalação do implante e da prótese provisória. Considerações finais: Concluiu-se que a instalação imediata de implantes após extração dentária é uma técnica segura e que apresenta excelentes resultados tanto em reabilitações em região anterior quanto para região posterior, além do mais esse procedimento tem se mostrado eficaz no restabelecimento da estética e função dentária.
Abordagem multidisciplinar no tratamento da síndrome metabólica: estrategias e desafios na clínica médica
Authors: Passos Jhon Rollyman Carvalho , De Carvalho Alexandre Nascimento Rezende , Cavalcante Lais Acácio , Quiodeto Isadora de Lima
Published: December 2023

A Síndrome Metabólica é uma condição complexa que aumenta o risco de doenças cardiovasculares e diabetes tipo 2. Inicia-se com uma exploração dos componentes da síndrome, como obesidade abdominal, dislipidemia, hipertensão, e resistência à insulina. Destaca-se a importância de uma equipe multidisciplinar na gestão eficaz da síndrome, envolvendo profissionais como endocrinologistas, nutricionistas, fisioterapeutas e psicólogos. Estratégias nutricionais, como a dieta mediterrânea, são recomendadas para combater os desequilíbrios metabólicos, enquanto a atividade física regular é enfatizada como essencial para a melhoria da saúde cardiovascular e controle glicêmico. O texto prossegue com uma discussão sobre o gerenciamento farmacológico, mencionando medicamentos para tratar a hipertensão, dislipidemia e alterações na glicemia. Além disso, aborda os desafios encontrados na prática clínica, como as barreiras à adesão do paciente e as dificuldades enfrentadas por populações de baixa renda e diversificadas.