bluuebunny/crossref_metadata_2025 huggingface dataset:
Multivariate mapping of cortical myeloarchitecture in the macaque cortex
Authors: Raven Erika , Bennett Jeffrey , Veraart Jelle , Lepage Claude , Charbonneau Joey , Bliss-Moreau Eliza , Zhang Jiangyang
Published: August 2023

Mapping cortical myelination has been a long-standing goal for accurate parcellation and classification of cytoarchitectonic boundaries. We investigated a multivariate myelin mapping approach for the accurate parcellation of small cortical subregions of the insula by exploiting the co-localization of iron with dense bands of myelin in cortical gray matter. We assessed the performance of multivariate myelin mapping in the rhesus macaque, both in vivo and ex vivo, and compared its performance with T1w/T2w ratio imaging. We demonstrated that multivariate myelin mapping is a translatable myelin sensitive technique for the differentiation of insula subregions.
Diagnostic value of NCE-CMRA in detection of inflammatory factors related coronary artery damage in Kawasaki disease
Authors: Liang Juan , Ma Yurong , Han Na , Ai Kai , Zhang Jing
Published: August 2023

This study mainly uses the non-contrast whole-heart magnetic resonance coronary angiography (NCE-CMRA) to evaluate coronary artery lesion (CAL) in children with Kawasaki disease (KD), and analyze the mechanism of inflammatory factors in the occurrence and development of coronary artery lesions in KD. Multiple linear regression was used to analyze the correlation between inflammatory factors and the severity of CAL. Platelet, PCT, ESR, CRP, D-dimer, albumin, and leukocyte have certain diagnostic value for KD, among which ESR is the most sensitive. Therefore, NCE-CMRA combined with inflammatory indicators is helpful for early diagnosis and prognostic evaluation of CAL in children with KD.
The application of REACT for central veins in patients with end-stage renal disease
Authors: Tao Fengming , Tao Li , Zhu Wei , Lv Fajin , Li Yongmei , YANG Haitao , Zhang Zhiwei , Jiang Ke
Published: August 2023

Relaxation-Enhanced Angiography without Contrast and Triggering (REACT) is a MR angiography technique without cardiac triggering, breath holding and contrast agent injection and is able to show robust blood-to-tissue contrast over multiple anatomies. This study aims to investigate the feasibility of REACT on central veins by comparing it with conventional CE-MRA and catheter angiography. Results showed that the image quality acquired from REACT was comparable to that from CE-MRA and there was no difference in central venous stenosis evaluated by REACT, CE-MRA and angiography.
3D free-breathing simultaneous whole heart T1 and T2 mapping based on SAturation Recovery and Variable flip Angle (SAVA)
Authors: Si Dongyue , Guo Rui , Liu Bowei , Herzka Daniel , Ding Haiyan
Published: August 2023

Myocardial T1 and T2 mapping enable quantitative detection of various cardiac diseases. Here we propose a fast 3D free-breathing simultaneous T1 and T2 mapping sequence, which acquires four volumes for joint estimation of T1 and T2. A very small flip angle is used for efficient sampling of the equilibrium longitudinal magnetization. Whole-heart T1 and T2 maps were acquired with high resolution of 1.5×1.5×4mm3 within 5 min in normal human subjects with image quality comparable to conventional 2D methods.
Left ventricular diastolic dysfunction in uncomplicated obesity: evaluated by CMR tissue tracking and volume-time curve
Authors: Liu Jing , Li Jing , Pu Huaxia , He Wenzhang , Li Xue , Zhou Xiaoyue , Tong Nanwei , Peng Liqing
Published: August 2023

This study evaluated left ventricular (LV) diastolic functional changes and left atrial (LA) functional indices using cardiac magnetic resonance (CMR) tissue tracking and volume-time curve in obese adults with no clinical signs or comorbidities. The association of LV diastolic function with fat distributions was also assessed. The results showed that CMR detected subclinical LV diastolic dysfunction, impaired LA reservoir and conduit function with preserved LV ejection fractions in adults with obesity. LV diastolic function was associated with LA reservoir and conduit function. Visceral fat was deleterious for LV diastolic function, while peripheral obesity might have had a protective effect.
Dual-domain self-supervised network for removing motion artifact related to Gadoxetic acid-enhanced MRI
Authors: Bao Qingjia , Pan Feng , Bai Chongxin , Liu Kewen , Li Zhao , Sun Peng , Wang Jiazheng , Zhong Linkun , Xiao Aodong , Yang Lian , Liu Chaoyang
Published: August 2023

We proposed a dual-domain self-supervised motion artifacts disentanglement network (DSMAD-Net) for the liver's gadoxetic acid-enhanced arterial phase images. The motion correction is converted to the image-to-image translation problem by assuming that motion-free images and motion-corrupted images belong to different domains. Specifically, image-to-image translation within the same domain is designed to constrain auto-encoders to learn the feature representation by utilizing the input images as supervision information. Moreover, the cross-domain translation explores the cycle consistency in the absence of paired motion-free and motion-corrupted images. Experimental results demonstrate that our method remarkably removes artifacts in the gadoxetic acid-enhanced arterial phase images.
Whole-Body Tumor Load ADC Histogram Analysis for Therapy Response Prediction and Evaluation for Multiple Myeloma
Authors: Gao Yuhan , Wang Qin , Zhang Lu , Xia Shuang , Zhu Jinxia , Grimm Rober , Stemmer Alto , Li Shuo , Liu Dong , Xue Huadan , Jin Zhengyu
Published: August 2023

This study aimed to explore the value of histogram analysis of apparent diffusion coefficient (ADC) maps for whole-body tumor load(WBTL) in predicting and evaluating the treatment response based on International Myeloma Working Group (IMWG) 2016 consensus criteria in patients with multiple myeloma (MM).Histogram analysis of ADC maps extracted eight parameters: mean, median, standard-deviation, entropy, skewness, kurtosis, ADC_5%, and ADC_95%. Seven parameters at baseline were significantly associated with therapy response. Three parameters in treatment percentage change were significantly associated with therapy response. ADC histogram analysis may be considered as an adjunct tool to the MM therapy response evaluation and prediction.
Differentiation of solid pseudopapillary tumor and neuroendocrine tumor of pancreas using DTI
Authors: Wang Xinqi , Wang Yi , Wang Lu , Zhang Qinhe , Xie Lizhi , Liu Ailian
Published: August 2023

It is difficult to differentiate the solidpseudopapillary tumer of the pancreas(SPTP) from pancreatic neuroendocrine tumers (PNET), due to their similar imaging characteristics. There was significant difference in DTI quantitative parameters Fractional Aniso (FA) and Volume ratio Aniso (VRA) between SPTP and PNET. The results showed that the FA and VRA values of DTI sequence of SPTP were significantly higher than that of PNET. Therefore, DTI sequences may be an effective method to identify SPTP and PNET.
Molecularly Targeted Magnetic Resonance Imaging and Spectroscopy
Authors: Yao Ye-Feng , Xin Jia-Xiang , Yang Guang , Zhang Huojun , Li Jiaqi , Fu Caixia , Wang Jiachen , Tong Rui , Wei Daxiu
Published: August 2023

This study developed a molecularly targeted magnetic resonance imaging/magnetic resonance spectroscopy (MRI/MRS) method to selectively probe a specific metabolite molecule of tissues/organs in vivo. Several biomolecules have been used for molecularly targeted MRI and MRS. We used N-acetyl aspartate (NAA)- and glutamate (GLU)-targeted 1H MRS spectra of the human brain and reported a novel approach to measure the local pH values of tissue in vivo.
Cerebral Blood Flow Autoregulation is a Major Contributor to Flow Dynamics of Cerebrospinal Fluid
Authors: Wang Yicun , van Gelderen Peter , de Zwart Jacco , Özbay Pinar , Mandelkow Hendrik , Picchioni Dante , Duyn Jeff
Published: August 2023

In addition to the well-established origin in cardiac and respiratory cycles, CSF pulsations may also result from the much slower variations in vascular tone associated with cerebral blood flow (CBF) autoregulation. Using a novel quantitative MRI approach, we measured CSF flow velocities and displaced volumes resulting from these three mechanisms in 12 healthy human controls. We found the autoregulatory effects to be a major factor, with associated CSF velocities comparable to and displaced volumes an order of magnitude larger than the cardio-respiratory effects. This may be an important mechanism underlying the CSF oscillations recently observed in resting-state fMRI.
Time-efficient, high resolution 3T whole brain relaxometry using 3D-QALAS with wave-CAIPI readouts
Authors: Gagoski Borjan , Cho Jaejin , Zhang Zijing , Kim Tae Hyung , Lo Wei-Ching , Polak Daniel , Warntjes Marcel , Cauley Stephen , Setsompop Kawin , Grant P. Ellen , Bilgic Berkin
Published: August 2023

Volumetric, high resolution, quantitative mapping of brain tissues’ relaxation properties is hindered by long acquisition times and signal-to-noise (SNR) challenges. This study, for the first time, combines the time-efficient wave-CAIPI readouts with the 3D-Quantification using an interleaved Look-Locker acquisition sequence with T2 preparation pulse (3D-QALAS) scheme, enabling full brain quantitative T1, T2 and proton density (PD) maps at 1.15 mm isotropic voxels in only 3 minutes at R=3x2 acceleration. When tested in both the ISMRM/NIST phantom and 7 healthy volunteers, the quantitative maps using the accelerated protocol showed excellent agreement against those obtained from conventional 3D-QALAS at RGRAPPA=2.
Free-running Simultaneous 3D Cardiac T1 Mapping and Cine Imaging Using a Linear Tangent Space Alignment Model
Authors: Djebra Yanis , Marin Thibault , Han Paul , Bloch Isabelle , El Fakhri Georges , Ma Chao
Published: August 2023

Cardiac T1 mapping allows assessment of tissue characteristics and functioning of the heart. However, existing methods are limited in terms of spatial resolution and coverage due to limitations in acquisition speed and the presence of cardiac and respiratory motion. This work proposes a new reconstruction framework for simultaneous, high-resolution 3D cardiac T1 mapping and cine imaging of the heart at 3T from sparsely sampled k-space data.
Determining Relative Diglyceride to Triglyceride Levels with STEAM MRS at 3 T
Authors: Saive Elliot , Fairgrieve-Park Logan , Yahya Atiyah
Published: August 2023

Diglyceride levels have been found elevated with some disease. Previously, STEAM (mixing time=TM=20ms) with an echo time (TE) of 100ms was shown to resolve triglyceride glycerol resonances from that of water of 3T while yielding adequate glycerol signal. The purpose of this work is to determine if STEAM with a TE of 100ms facilitates relative quantification of diglyceride/triglyceride levels at 3 T. Spectra were measured from phantoms containing 1,3-dicaprylin/tricaprylin with varying weight/weight contents of 2.5%/97.5%, 5%/95%, 10%/90% and 20%/80%. Concentration ratios of 1,3-dicaprylin/tricaprylin estimated from STEAM (TM=20ms, TE=100ms) resulted in a linear correlation with expected concentration ratios (R2 > 0.99).
Large benefit of RF coil B1 efficiency for X-nuclear MRS at ultrahigh field beyond the gyromagnetic ratio advantage of proton
Authors: Li Xin , Wiesner Hannes , Zhu Xiao-Hong , Chen Wei
Published: August 2023

In this study, we conducted electromagnetic simulation of a surface loop coil to quantify the B1+ transmit efficiency of five nuclei ( 1H, 31P, 23Na, 2H and 17O) from 1.5T to 21 T field strength. The simulation is validated by FID measurements. Furthermore, we investigated the loading effect on the RF coil B1+ transmit efficiency and its dependence on B0. Our study shows the X-nuclei flip angle can be reached using the same or even less coil driving voltage as for proton, thus, significantly reducing the required RF power and SAR concern.
Microstructure changes of the normal-appearing white matter in the Corpus Callosum in Relapsing-Remitting Multiple Sclerosis
Authors: Melie-Garcia Lester , Barakovic Muhamed , Weigel Matthias , Rahmanzadeh Reza , Galbusera Riccardo , Lu Po-Jui , Cagol Alessandro , Lutti Antoine , Schaedelin Sabine , Benkert Pascal , Todea Alexandra , Ruberte Esther , Radue Ernst-Wilhelm , Kappos Ludwig , Kuhle Jens , Granziera Cristina
Published: August 2023

A scarce body of literature studies the Corpus Callosum (CC) normal-appearing white matter (NAWM) in Relapsing-Remitting Multiple Sclerosis (RRMS). This work aimed to characterize the degree of the alterations in different CC segments by assessing the extent of damage to myelin and axon, as measured with myelin volume fraction, axonal volume fraction, and g-ratio. These microstructural measures correlated with disease duration, EDSS, number, and volume of the lesions in other white matter regions. In sum, this work shows that CC pathology in RRMS patients is related to focal damage and/or diffuse neurodegeneration, which is clinically relevant.
Influence of gadoxetate disodium to the liver fat fraction quantified with Dixon sequences in rabbits
Authors: Huang Zhe , Jiang# Yu , Wang# Xia , Zhang# Sheng , Li# Heng , Han* Dong
Published: August 2023

A study was carried out on the effect of Gadoxetate disodium (Gx) on the accuracy of liver fat content determined by 2-echos and 6-echos VIBE Dixon in rabbits with nonalcoholic fatty liver disease in hepatobiliary specific phase. Proton density fat-fraction (PDFF) before and 13min. and 17min. after Gx enhancement had strong correlation with that of histopathology (r22E= 0.7643-0.8014 vs. r26E= 0.8208-0.8536). PDFF measured by 6E-VIBE Dixon was stable and reliable, especially for that before Gx enhancement(r26E= 0.8536). PDFF measured by 2E-VIBE Dixon fluctuated to some extent, however, it could be effectively corrected in the specific hepatobiliary phase after Gx enhancement.
Single-Shell Free Water Imaging by Synthetic Q-Space Learning
Authors: Masutani Yoshitaka , Sasaki Koh
Published: August 2023

Free water imaging (FWI) belongs to the dMRI family, and is an extention of the DTI model by adding the isotropic diffusion compartment. Conventionally, FWI parameters have been obtained by numerical fitting to measured signal values of DWI of single-shell or multi-shell. It has been reported that it is harder to obtain robust results in single shell data. Recently, machine learning techniques have shown promising results in dMRI parameter inference. In this study, we aimed at FWI parameter inference from single-shall dMRI data by using synthetic Q-space learning. Several validation experiments by quantitative and visual assessments were performed.
Microstructural Basis of Fractional Anisotropy Difference Associated with b-value in Diffusion MRI
Authors: Yao Junye , Zhou Zihan , Tendler Benjamin , Miller Karla , Lei Hao , Zhang Lei , Bao Aimin , Zhong Jianhui , He Hongjian
Published: August 2023

The microstructural basis of b-value dependence on FA was investigated in the human brain, using in vivo MRI and a formalin-fixed human brain hemisphere. Consistent decreases of FA with increasing b-values were observed both in vivo and ex vivo. The percentage difference of FA (pdFA) between high and low b-value datasets was found to increase with neurite density estimated from NODDI, which was further validated using histology and a multi-compartment model simulation. Results indicate that the b-value dependence of FA can be explained by compartmental differences between intra- and extra-neurites.
3D Pseudo-Continuous Arterial Spin Labeling Acquisition using a High-Performance Gradient System: A Scan Time and Image Quality Assessment
Authors: Ajala Afis , Lee Seung-Kyun , Kang Daehun , Marinelli Luca , Yeo Desmond Teck Beng , Foo Thomas
Published: August 2023

The maximum gradient amplitude (Gmax) and slew rate (SRmax) determine the minimum number of interleaves (and total scan time) in a 3D pseudo-continuous arterial spin-labeling (3DpCASL) acquisition with a stack-of-spirals readout module for a given spatial resolution. The higher Gmax and SRmax of a recently developed head-only gradient system (MAGNUS) was utilized to reduce the total scan time of a clinical 3DpCASL acquisition by a factor of 2 compared to a similar acquisition carried out at a lower Gmax and SRmax of a conventional whole-body system (CWBS) while maintaining comparable image quality.
Preservation of Human Hearts for Transplantation: Comparison of Metabolic Indicators after Conventional and Temperature Controlled Storage
Authors: Sharma Gaurav , Vela Ryan , Powell LaShondra , Deja Stanislaw , Mizerska Monika , Jessen Michael , Burgess Shawn , Malloy Craig R. , Peltz Matthias
Published: August 2023

Preservation of human hearts for transplantation is important to optimize outcomes. Standard ischemic cooling methods are intended to preserve high energy phosphates but risk tissue damage due to freezing; an alternative with precise temperature control has emerged as an option. The efficacy of this technique in preserving high energy phosphates and other metabolites has not been examined. We compared conventional cold storage to a commercial device with precise temperature control for preservation of human hearts not suitable for transplant. There were no significant differences in high energy phosphates or other metabolites using precise temperature control compared to conventional cold storage.
MIRTorch: A PyTorch-powered Differentiable Toolbox for Fast Image Reconstruction and Scan Protocol Optimization
Authors: Wang Guanhua , Shah Neel , Zhu Keyue , Noll Douglas , Fessler Jeffrey
Published: August 2023

MIRTorch (Michigan Image Reconstruction Toolbox for PyTorch) is an image reconstruction toolbox implemented with native Python/PyTorch. It provides fast iterative and data-driven image reconstruction on both CPUs and GPUs. Researchers can rapidly develop new model-based and learning-based methods (i.e., unrolled neural networks) with its convenient abstraction layers. With the full support of auto-differentiation, one may optimize imaging protocols, such as sampling patterns and image reconstruction parameters with gradient-based methods.
Sample size considerations for structural covariance using T1-weighted brain imaging from the UK Biobank
Authors: Kim William , Jiang Guocheng , Luciw Nicholas , MacIntosh Bradley
Published: August 2023

Anatomical T1-weighted imaging allows us to examine relationships of regional morphology across the brain through structural covariance. Here, we investigated structural covariance stability using decreasing amounts of T1-weighted imaging data from the UK Biobank. Starting from 1,753 individuals, we found that it is possible to drastically reduce the sample and still maintain adequate stability (78% agreement with ~87 individuals). We note, however, that stability was regionally variable; lateral and cortical regions were least affected by sample size while medial and subcortical regions were most affected. These findings may inform sample size considerations for MRI-based structural covariance in large population studies.
Spikes-on-demand. A simple method to generate realistic spikes to test artifact detection algorithms
Authors: Sidhu Jagjit , Sakaie Ken , Nemani Ajay , Lowe Mark
Published: August 2023

Quality assurance (QA) protocols can and should be used to proactively detect low-level spiking and other artifacts early so that these problems can be remedied before becoming more debilitating and adding significant overhead to the image analysis workflow. However, one generally needs corrupted data sets to test the accuracy of the novel algorithm. This prevents researchers from taking a proactive stance of establishing these QA protocols before corruption of data sets occurs. Here, we detail a simple method to generate spikes reliably and reproducibly to generate corrupted data that can be used to test and debug any new QA algorithms.
The Pericope of the Adulteress (John 7:53–8:11)
Authors: Wasserman Tommy , Knust Jennifer
Published: August 2023

N/A
Jesu död i Markusevangeliet – skamlig eller ärofull?
Authors: Vasquez Victoria
Published: August 2023

N/A
RNA Sequencing for Solid Tumor Fusion Gene Detection: Proficiency Testing Practice and Performance Comparison
Authors: Bridge Julia A. , Halling Kevin C. , Moncur Joel T. , Souers Rhona J. , Hameed Meera R. , Fernandes Helen , Roy Angshumoy , Surrey Lea , Tafe Laura J. , Vasalos Patricia , Lopez-Terrada Dolores H.
Published: August 2023

Context

Next-generation sequencing–based approaches using RNA have increasingly been used by clinical laboratories for the detection of fusion genes, intragenic rearrangements, and exon-skipping events. Correspondingly, the College of American Pathologists (CAP) has advanced RNA sequencing proficiency testing (PT) to ensure optimal performance of these assays.

Objective

To report on laboratory performance and practices of RNA sequencing for the detection of fusion genes, intragenic rearrangements, and exon-skipping events using CAP PT data from 8 mailings (2018-A through 2021-B).

Design

CAP PT RNA sequencing program results from 153 laboratories across 24 proficiency test specimens, interrogating 22 distinct engineered fusion transcripts, were analyzed for correct identification of the fusion event, associated performance variables, and laboratory practices.

Results

Overall, the 4-year program detection rate (sensitivity) was 95.5% (1486 of 1556 results). False-negative rates were 3.6% (53 of 1463) and 18.3% (17 of 93) for fusion gene and intragenic rearrangement/exon-skipping events, respectively. Only 19 false-positive results were reported among the 8 PT mailings, and most were likely the result of preanalytical or postanalytical errors. There were no practice characteristics (eg, instrumentation, sequencing method) significantly associated with the fusion detection results.

Conclusions

These data reveal a high overall sensitivity and specificity for fusion gene detection by participating laboratories using clinical RNA sequencing. Performance was comparable across all laboratories, regardless of methodology. The fraction of false-negative results for intragenic rearrangement/exon-skipping events was greater than that for the chimeric fusion genes. False-negative results could not be attributed to any specific practice characteristics.
Supply Chain Measuring Performance with Scor Model Business Process Mapping
Authors: Wahyudi Wahyudi , Haliah Haliah , Kusumawati Andi
Published: August 2023

This study provides a general framework for measuring general supply performance. This research uses business process mapping with the Supply Chain Operations Reference (SCOR) model. Data collection methods by interviews, observations, document inspections, and literature studies. The findings of this study show that the business processes of PT Semen Bosowa Maros have been implemented well. Of the 12 performance measurement metrics used, there are 8 metrics with details, namely: internal meeting, planning cycle time, source defect rate, source fill rate, failure in the process, orders ready to pick by a customer, customer complaint, and return rate has been in an excellent position (excellent). Three other metrics have been in a good position: source lead time, machine efficiency, and delivery fill rate. Only the forecast accuracy metric is in a marginal position
Community Business Action Plan Based on Regional Potential in The Framework of Agrarian Reform
Authors: Nugroho Aristiono
Published: August 2023

Sentang Village, Wonogiri District, Wonogiri Regency needs a community business action plan based on regional potential within the framework of agrarian reform. The action plan contains a plan of activities that need to be carried out by the village government, to develop community businesses within the framework of agrarian reform, for the improvement of community welfare. This research uses qualitative research methods, with a rationalistic approach. The number of informants was 10, purposively selected. The data consists of: (1) Primary data, obtained from interviews with informants; (2) Secondary data, in the form of population data in Sentang Village. Meanwhile, data analysis is carried out by utilizing qualitative data analysis techniques. The results of this study show that the action plan is prepared by taking into account physical and non-physical potentials, as well as the economic contribution of business fields in Sentang Village, which include: (1) agricultural business, (2) livestock business, (3) fisheries business, (4) trading business, (5) handicraft business, and (6) tourism business. Action plan provides benefits in the form of community welfare, consisting of: (1) economic welfare, (2) psychological welfare, (3) social welfare, and (4) cultural welfare
Prioritas Fakir Miskin dalam Pembagian Zakat
Authors: Abbas Afifi Fauzi
Published: August 2023

Zakat merupakan ibadah maliyah Ijmaiyah (ibadah) yang berkaitan dengan ekonomi, keuangan dan kemasyarakatan) dan merupakan salah satu dari rukun Islam yang mempunyai status dan fungsi yang amat vital dalam syari'at Islam. Oleh karena Al-Quran menegaskan kewajiban zakat bersama dengan kewajiban sholat. Zakat itu sebenarnya adalah: mengeluarkan sebahagian dari harta benda atas perintah Allah, sebagai shadaqah wajib kepada mereka yang telah ditetapkan menurut syarat-syarat yang telah ditentukan oleh syari'at. Zakat dipungut dari orang-orang yang mampu, dan diberikan kepada orang-orang yang berhak menerimanya. Jadi tempat menarik zakat itu, dari orang-orang kaya yang memiliki nishab.
Periode Perkembangan Darulfunun El-Abbasiyah 1854-2020
Authors: Afifi Abdullah A , Abbas Afifi Fauzi
Published: August 2023

Darulfunun's long journey in the world of education, especially in Islamic education in Indonesia nearly entered two centuries. From it starts, Darulfunun already persevered through varieties of circumstances in serving education for benefiting the society. Darulfunun concern in developing Islamic education already tested in their long journey and innovations that they share with Indonesia modern Islamic education today. Darulfunun established the moderated education concept that combines sciences and religion as one integrated knowledge. In addition, Darulfunun reformed the non-curriculum halaqah education into the classroom education curriculum. In its transformation, the thought and methods promoted by Darulfunun are genuinely become a treasure for education society and Islamic thought in Indonesia. This article aims to outline the development periods of Darulfunun with the specific characteristics of each period. Each period is explored by the important events and changes that make it different from other periods. From the observations, it can be presumed that innovation and development carried out by Darulfunun is a significant effort to adjust to the global challenges and participate in solving problems in society.
Pengembangan Kurikulum Moderasi Islam (Wasathiyyah) dan Karakter Muslim Moderat yang Bertakwa di dalam Lingkungan Muhammadiyah
Authors: Abbas Afifi Fauzi , Afifi Abdullah A
Published: August 2023

Pengembangan konsep moderasi Islam (wasathiyyah) menjadi tulang punggung dalam membentuk Islam yang berkemajuan di Indonesia. Pengembangan pendidikan di kalangan Muhammadiyah menjadi salah satu kontribusi besar pengembangan gagasan ke-Indonesia-an dan pendidikan di Indonesia. Kurikulum pendidikan yang dikembangkan Muhammadiyah adalah respon dari perubahan sosial budaya, tantangan-tatangan yang dihadapi pendidikan di Muhammadiyah, dan pendidikan di Indonesia secara umumnya. Kurikulum-kurikulum yang dikembangkan terus dievaluasi dan diperbaiki untuk dapat memberikan hasil manusia moderat (wasathiyyah) dan berkemajuan (islah wa maslahah). Pada akhirnya upaya dari pengembangan pendidikan adalah mengharapkan siswa didik yang seimbang imtak dan iptek, dan pada akhirnya dapat menjadi solusi rahmatan lil alamin. Tulisan ini adalah ulasan dari pengalaman keterlibatan penulis dalam pengembangan pendidikan di Muhammadiyah.
Evaluating Organizational Outcomes (Oos) of One State University in the Philippines: Basis for Policy Recommendation and Adoption
Authors:   Associate Professor V College of Teacher Education Laguna State Polytechnic University, G. Roman Adriel
Published: August 2023

Higher Education Institutions in the Philippines are mandated to perform three major functions-Instruction, Research, and Extension while ensuring their sustainability through a sound Management of Resources. This study presents the Organizational Outcome (OOs) of one state university in the Philippines in the past three years (2020-2022) during the onslaught of the COVID19 pandemic. It was hypothesized in the study that the performances of the university differ from 2020-2022. Using descriptive evaluative design and document analysis techniques, the study collected data and documents from the website of the university. Verification of gathered data was done through an interview with the heads of the units directly involved in the indicators per parameter. Based on the results, the university has surpassed all the targets for each parameter in the Organizational Outcome (OOs) and no significant difference was found in the parameters from 2020-2022. Finally, the study provides recommendations such as policy interventions on the performance indicators which were found in the critical region of accomplishments.
Leadership Question and the Writer’s Style: A Literary Stylistic Analysis of Adaobi Nwaubani’s I Do Not Come to You By Chance
Authors:   Department of English Akwa Ibom State University Akwa Ibom State, Nigeria, Akpan Isonguyo
Published: August 2023

This paper interrogates some artistic positions taken by Adaobi Nwaubani in projecting leadership issues in I Do Not Come to You by Chance. The paper notes that in spite of the enormity of critical attention on leadership in African critical space, bulk of the critical materials center around the ineptitude of African leaders and its consequent underdevelopment of African societies and the suffering of the mass. Literary critics hardly pay attention to those artistic positions through which authors project leadership issues in their texts. It is against this backdrop that this paper is dedicated for interrogation of some aspects of literary techniques, through which Nwaubani addresses leadership issues in her text. The work reveals how the author uses characterization and setting to expose the corrupt nature of most political leaders in Nigeria, their gluttony, and the deteriorating nature of some public institution. It has also revealed the complicit roles played by former colonial masters, and world institutions in entrenching criminality in Africa, especially in the Nigerian leadership. The paper concludes that both contents and form are very critical in understanding a literary work and so, an analysis of one at the expense of the other may scuttle the totality of the import of the issues authors raise in their texts.
Selecting Green Supplier for Perishable Raw Materials using AHP Method at Nunia Boutique Villa Seminyak
Authors: Paramita Komang Devi , Nadra Nyoman Mastiani , Winia I Nyoman , Mudana I Gede , Anggraheni Raden Roro Rieta
Published: August 2023

Purpose: The aim of this research is to do the selection for green supplier for perishable raw material at Nunia Boutique Villa, Villa with 8 Units Villa located at Seminyak Badung Bali.

Research methods: One of the methods that used in this research is Analytical Hierarchy Process (AHP) method with Vendor Performance Index (VPI) is a Quality, Cost, Delivery, Flexibility, and Responsiveness (QCDFR) by adding the Environment Management criteria. This research used the AHP method with the expert choice software.

Findings: The final rating of relative importance’s supplier selection criteria was found: the Quality criteria (0.472) was ranked first in the order of priority in the green supplier selection criteria.

Implication: The Cost criteria with 0.192, Environment Management criteria (0.102), Delivery criteria (0.091), Flexibility criteria (0.076) and the last criterion is Responsiveness (0.067).
Analysis of Green Practices Implementation at FourStar by Trans Hotel Restaurant
Authors: Putra Gede Ari Ambara , Bagiastuti Ni Ketut , Astuti Ni Nyoman Sri , Suparta I Ketut , Suja I Ketut
Published: August 2023

Purpose: This study aims to determine the implementation of green practices that have been implemented and which need to be improved at the FourStar by Trans Hotel restaurant. Green Practice is an action to protect the environment and the resulting product is less damaging to the environment. Restaurants that imple-ment green practice usually focus on reduce, reuse, and recycle as well as energy and efficiency.

Research methods: The research data were sourced from participatory interview and observation methods at the research location which were then processed us-ing triangulation techniques.

Findings: The results of the study show that the implementation of green practic-es has been implemented properly and adequately in restaurants although there are several indicators of green practice that still need to be improved.

Implication: Indicators that need to be maintained include the use of recyclable containers, the use of energy-efficient lighting and the use of a temperature com-fort control system, as well as the installation of signs and policies that need to be implemented, and indicators that need to be improved are educating the pub-lics about green practices in a sustainable manner, Implementing funding for ac-tivities that support environmentally friendly direction and donating organic wastes as the use of animal feed for the community.
Extinction in finite time of solutions to fractional parabolic porous medium equations with strong absorption
Authors: Dao Nguyen Anh
Published: August 2023

In this article we study the solutions of a general fractional parabolic porous medium equation with a non-Lipschitz absorption term. We obtain the existence of weak solutions, \(L^p\)-estimates, and decay estimates. Also, we show that weak solutions must vanish after a finite time, even for large initial data.
For more information see https://ejde.math.txstate.edu/Volumes/2021/29/abstr.html
Tempo e espaço da disciplina de didática nos cursos de pedagogia
Authors: Domit Juliana , Romanowski Joana Paulin
Published: August 2023

O objeto do estudo se refere ao tempo e espaço da disciplina de Didática nos cursos de Licenciatura em Pedagogia no Brasil. O problema investigado toma como questão principal: o tempo e espaço da disciplina de Didática nos cursos de pedagogia favorece a formação docente? O objetivo geral é compreender o tempo e espaço da disciplina de didática na formação inicial de professores no curso de Pedagogia. O pressuposto entende a disciplina de Didática, de natureza pedagógica, comprometida com as questões concretas da docência, se constitui eixo central para os cursos de formação inicial de professores. A escolha da licenciatura em Pedagogia é intencional por ser este curso destinado à formação de professores para os anos iniciais do ensino fundamental e educação infantil. Metodologicamente o estudo assume a abordagem cartográfica (ROSÁRIO, 2008), a partir do mapeamento do curso de Pedagogia nas universidades federais brasileiras. Para a realização do estudo foi feita a leitura das matrizes curriculares de 61 cursos e a leitura dos Projetos Políticos Pedagógicos (PPPs). Os aportes teóricos fundamentam-se em Candau (1984), Gatti (2019), Marins (2015), Martins (2009,2012), Romanowski (2010,2016) e Veiga (1994, 2012). Os dados levantados permitem considerar que a disciplina de Didática está presente em todos os cursos de Pedagogia nas universidades federais brasileiras. A pesquisa reconheceu que há três eixos de disciplinas de didática nas propostas do curso: a Didática Geral, as Didáticas Específicas e as Didáticas para as modalidades de ensino.
Red blood cell distribution width (RDW) is a significant predictor of survival in laryngeal cancer patients: Systematic literature review and meta-analysis
Authors: Nocini Riccardo , Sanchis-Gomar Fabian , Lippi Giuseppe , Mattiuzzi Camilla
Published: August 2023

Background: This systematic literature review and meta-analysis investigated whether the red blood cell distribution (RDW) may predict survival outcomes in laryngeal cancer patients undergoing curative treatment. Methods: We conducted an electronic search in Medline and Scopus using the keywords "red blood cell distribution width" OR "RDW" AND "laryngeal cancer" OR "larynx cancer" OR "laryngeal carcinoma" OR "larynx carcinoma," without time or language restrictions (up to February 2023), for identifying studies investigating the prognostic value of RDW in patients with any form of laryngeal cancer and with a primary endpoint that was set as survival rate and/or disease-free survival between 1 and 10 years after curative treatment. The research was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 reporting checklist. Results: The digital search enabled us to identify five studies, that were finally included in our pooled analysis (survival rate and/or disease-free survival covered a window between 2.7-8.3 years). In four of the five studies, an enhanced RDW value in laryngeal cancer patients undergoing surgical or radiation treatment was associated with poorer survival (range of odds ratio ORs, 2.28-10.44). In the pooled analysis, increased RDW conferred an over 3fold higher risk of dying during follow-up after curative treatment for laryngeal cancer (OR, 3.37; 95%CI, 1.41-8.10). Conclusion: RDW retains a clinically important prognostic value in patients with laryngeal cancer undergoing curative treatment. Clinicians could acknowledge this information for using a more aggressive therapy or setting narrower follow-up in laryngeal cancer patients with increased RDW values.
Pengembangan Kader Sadar Wisata Desa Lohia Melalui Penguatan Strategi Komunikasi Parawisata
Authors: Maulana Harry Fajar , Hastuti Hastuti , Ferdi Ferdi , Mutmainah Mutmainah , Maulana Reza
Published: August 2023

Desa Lohia adalah sebuah desa wisata dekat Danau Napabale, serta Pantai Meleura, tujuan wisata populer di Kabupaten Muna. Karena Kawasan desa Lohia berjarak lebih dari 2 (dua) kilometer dari Kota Muna Kurnag, ada program yang tersedia bagi wisatawan yang berkunjung ke desa tersebut. Tujuan dari PKM ini adalah untuk menciptakan mitra yang akan menjadi pusat model pertumbuhan ekonomi kerakyatan dan kesejahteraan masyarakat jangka panjang dengan memanfaatkan potensi desa wisata di Desa Mangunan melalui taktik komunikasi pariwisata. Berikut ini adalah beberapa teknik yang digunakan dalam pemberdayaan masyarakat: Program pelatihan pengabdian masyarakat dihasilkan menggunakan teknik yang disederhanakan, khususnya dengan melakukan sarasehan dan percakapan santai/informal agar masyarakat tidak terbebani dengan materi pelatihan. Materi pelatihan yang disampaikan meliputi berbagai studi kasus dan praktik terbaik dalam pengelolaan desa pariwisata, memberikan peserta pelatihan gambaran umum tentang isu dan taktik yang harus dilaksanakan. Tujuan dari pendekatan pelatihan yang mencakup dialog informal adalah untuk mendorong keterlibatan aktif yang lebih besar dan perhatian dari peserta. Penguatan Desa Wisata Kungkuk merupakan konsekuensi dari upaya ini, yang dilakukan melalui pembangunan dan pengembangan forum pariwisata yang tangguh. Berdasarkan pengamatan, strategi kelompok sadar wisata untuk memperkuat desa wisata napabale dan desa wisata pantai maleura telah berjalan cukup baik. Hal ini didukung dengan temuan wawancara yang dilakukan dengan beberapa informan, yang menyatakan bahwa strategi tersebut telah dilakukan dengan baik hanya dalam penerapannya, yaitu kurangnya koordinasi antara pokdarwis dan masyarakat, sehingga masih ada masyarakat di sana. Desa Wisata Pantai Maleura dan Desa Napabale.
Peningkatan Pemahaman Hukum Investasi Mata Uang Kripto di Indonesia
Authors: Heradhyaksa Bagas
Published: August 2023

Perkembangan teknologi yang semakin mudah diakses masyarakat menjadikan masyarakat lebih mudah dalam mengakses informasi. Salah satu informasi tersebut adalah mengenai literasi keuangan. Semakin banyak masyarakat Indonesia yang memahami konsep investasi. Khususnya para milenial yang sehari-hari sudah tidak asing gadget. Salah satu bentuk investasi yang sedang booming akhir-akhir ini adalah investasi mata uang kripto. Namun begitu, banyak infromasi salah yang mempengaruhi para milenial dalam melakukan investasi tersebut. Pengabdian ini bertujuan untuk memberikan pemahaman yang komprehensif tentang investasi mata uang kripto berdasarkan undang-undang, literatur terkait serta fatwa MUI. Sasaran dari pengabdian ini adalah mahasiswa KKN UIN Walisongo. Pengabdian dilaksanakan dengan metode Participatory Action Research (PAR). Hasil dari pengabdian ini berhasil merubah pemahaman para peserta sasaran pengabdi mengenai investasi mata uang kripto. Hal ini menjadi penting agar para sasaran pengabdi tidak salah dalam bertindak ketika ingin malkukan investasi mata uang kripto. Diharapkan, para peserta sasaran pengabdi dapat melakukan transfer of knowledge kepada seluruh elemen masyarakat mengenai konsep investasi mata uang kripto yang sesuai dengan aturan yang berlaku
Keterampilan Public Speaking dalam Konten Edukatif Melalui Media Tiktok pada Remaja Karantaruna Desa Wajah Jaya
Authors: Nastia Nastia , Hastuti Hastuti , Maulana Harry Fajar , Susanto Rio Irwan , Aldin Aldin , Rasyid La Ode Muhammad
Published: August 2023

Di era digital komunikasi mempunyai peran penting dalam berkomunikasi. Situasi remaja berperan aktif dalam hal public speaking dalam meningkatkan kemampuan dalam berbicara. Berbicara didepan umum dapat berkembang sehingga unutk berbicara dapat mengekspresikan ide dengan benar sehingga pendengar dapat memahami semua yang ingin dikatakan. Pendekatan tatap muka dan metode evaluasi digunakan dalam kegiatan ini. Penyaluran materi secara langsung adalah bagaimana metode tatap muka dilakukan. Pertemuan pertama dibagi menjadi dua sesi, masing-masing berlangsung selama dua jam. Para jamaah memberikan ice breaker berupa permainan-permainan yang menyenangkan pada sesi pertama untuk mencairkan suasana terlebih dahulu. Peserta workshop ini mendapatkan materi pelatihan dan alat tulis dari para penyembah. Kegiatan Pengabdian kepada masyarakat dosen Fakultas Ilmu Sosial dan Ilmu Poltik Universitas Muhammadiyah Buton dilaksanakan dimulai tanggal 10, 11, dan 12 Maret 2022 yang berlangsung selama 3 pertemuan. Pada setiap pertemuannya dibagi menjadi 2 sesi. Peserta pelatihan berjumlah 45 orang, selurunya adalah anggota Remaja Karantaruna Desa Wajajaya.Kegiatan dimulai dari pukul 09.00 sampai pukul 11.00, bertempat di Desa Wajajaya, Kecamatan Lasalimu Selatan, Kabuptaen Buton. Berdasarkan hasil kuisioner yang dikeluarkan, 86% anak remaja karataruna desa wajajaya memahami materi pelatihan. Oleh karena itu, dapat dikatakan bahwa menggunakan media pebajalaran sebagai alternatif meningkatkan kemampuan berbicara di depan umum untuk konten pendidikan
Factores maternos asociados al bajo peso en recién nacidos en el servicio de neonatología del hospital Sergio Enrique Bernales–2018
Authors:   , Paredes Barrera Angela Karina
Published: August 2023

Objetivo: Determinar los factores maternos asociados al bajo peso en recién nacidos en el servicio de neonatología del Hospital Sergio E. Bernales 2018. Materiales y Métodos: El tipo de estudio observacional, que es analítico de tipo casos y controles, que se realizó en tiempo retrospectivo y de recolección de datos se realizó de manera transversal. La población incluida en el presente estudio fue de 106 mujeres que culminaron el embarazo con un recién nacido de bajo peso, y mediante la aplicación de una prueba estadística en el programa Epidat v 4.2, y basándose en un estudio previo se halló que eran necesarios 43 casos y 43 controles, y los datos obtenidos y recopilados se pasaron en un programa de Microsoft Office Excel 2010, que posteriormente se exporto al programa estadístico SPSS v.p25, en el cual se procesaron las tabulaciones estadísticas como Chi-cuadrado, para la determinación de asociación. Resultados: Se halló que dentro de los casos que tenían una edad entre 20 a 35 años, se presentó en un 55.8%(24); asimismo, no hubo asociación estadísticamente significativa (X2=1.251, p-valor≥0.05). La anemia gestacional se presentó en el 76.7%(33) de todos los casos; y se encontró una asociación estadísticamente significativa (X2=20.556; p-valor=0.000). Asimismo, el insuficiente número de controles prenatales tienen asociación con respecto al bajo peso en recién nacidos (X2=8.142; p-valor=0.004), IC: 95%; 1.476-9.146). La prematuridad es un factor materno que presenta una asociación estadísticamente con el bajo peso en recién nacidos (X2=51.093; p-valor=0.000), al igual que la presencia de preeclampsia durante el embarazo (X2=11.328; p-valor=0.001). Conclusiones: Se concluye que los factores maternos asociados al bajo peso en recién nacidos, son la anemia gestacional, presencia de preeclampsia, inadecuado control prenatal, ITU, y prematuridad.
Nivel de satisfacción y fatiga por compasión en profesionales de salud del primer nivel de atención en Lima, 2021
Authors:   , Canduelas Villavicencio Alva Luz Milagros
Published: August 2023

Objetivo: Describir la prevalencia de satisfacción y fatiga por compasión en profesionales de salud de dos establecimientos del primer nivel de atención del MINSA durante mayo y junio del 2021. Materiales y métodos: Se realizó un estudio observacional, descriptivo, transversal, prospectivo y la muestra estuvo conformada por 92 profesionales de la salud seleccionados mediante un muestreo probabilístico aleatorio por conglomerados. Se utilizó como instrumento el cuestionario ProQOL-vIV que fue previamente traducido y validado. El cuestionario fue aplicado mediante encuestas y se determinaron los niveles de satisfacción y fatiga por compasión mediante estadística descriptiva. Resultados: La muestra estuvo caracterizada por una edad promedio de 41 años, género femenino y solteras; la profesión predominante en ambos establecimientos de salud fue heterogénea, siendo en uno obstetras (40,3%) y en el otro (33,8%) diferente a médico, obstetra o enfermero. Respecto al nivel de satisfacción y fatiga por compasión, en ambos establecimientos de salud, el nivel de satisfacción fue alto (60,0%), sin embargo, el nivel de fatiga por compasión fue medio, tanto en la fatiga secundaria a trauma (60,7%) como en el síndrome de burnout (73,8%). Conclusiones: El nivel de satisfacción por compasión de los profesionales de la salud en ambos establecimientos fue alto, a pesar de que el nivel de fatiga por compasión fue medio.
Infección del tracto urinario como factor de riesgo para el desarrollo de amenaza de parto pretermino en gestantes atendidas en el Hospital Nacional Sergio E. Bernales de julio a diciembre del 2020
Authors:   , Martínez Ramos Alfredo Jhonatan
Published: August 2023

Objetivo: Determinar la asociación entre infección del trato urinario y desarrollo de amenaza de parto pretérmino. Materiales y Métodos: El tipo de estudio fue observacional, analítico, de casos y controles, retrospectivo, y transversal. La población incluida en el estudio fueron la totalidad de pacientes que presentaron amenaza de parto pretérmino, las cuales fueron un total de 140 gestantes atendidas en el Hospital Nacional Sergio E. Bernales entre Julio a Diciembre del año 2020. Se realizó un análisis bivariado mediante SPSS Statistics versión 26, además se estudió características en la población como edad, número de controles prenatales, paridad y antecedente de parto pretérmino. Resultados: Respecto a la amenaza de parto pretérmino, la infección del tracto urinario es un factor de riesgo ya que tiene un OR= 3.009, los controles prenatales incompletos tienen un OR= 3.9, el antecedente de parto pretérmino tiene un OR= 2.843 y respecto a la paridad tiene un OR= 0.353, siendo este último el único factor protector encontrado en el presente estudio con respecto a las variables estudiadas. Conclusiones: La infección del tracto urinario es un factor de riesgo para la amenaza de parto pretérmino. Se debe reforzar las medidas preventivas a las mujeres gestantes y en edad fertil, disminuyendo asi la infección del trato urinario para lograr una menor incidencia en la amenaza de parto pretermino, evitando asi el parto pretermino, el cual conlleva a un incremento en la morbi mortalidad neonatal.