bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparison of Knee Abduction Angles Measured by a 3D Anatomic Coordinate System Versus Videographic Analysis: Implications for Anterior Cruciate Ligament Injury
Authors: Englander Zoë A. , Cutcliffe Hattie C. , Utturkar Gangadhar M. , Garrett William E. , Spritzer Charles E. , DeFrate Louis E.
Published: January 2019

Background:

Knee positions involved in noncontact anterior cruciate ligament (ACL) injury have been studied via analysis of injury videos. Positions of high ACL strain have been identified in vivo. These methods have supported different hypotheses regarding the role of knee abduction in ACL injury.

Purpose/Hypothesis:

The purpose of this study was to compare knee abduction angles measured by 2 methods: using a 3-dimensional (3D) coordinate system based on anatomic features of the bones versus simulated 2-dimensional (2D) videographic analysis. We hypothesized that knee abduction angles measured in a 2D videographic analysis would differ from those measured from 3D bone anatomic features and that videographic knee abduction angles would depend on flexion angle and on the position of the camera relative to the patient.

Study Design:

Descriptive laboratory study.

Methods:

Models of the femur and tibia were created from magnetic resonance images of 8 healthy male participants. The models were positioned to match biplanar fluoroscopic images obtained as participants posed in lunges of varying flexion angles (FLAs). Knee abduction angle was calculated from the positioned models in 2 ways: (1) varus-valgus angle (VVA), defined as the angle between the long axis of the tibia and the femoral transepicondylar axis by use of a 3D anatomic coordinate system; and (2) coronal plane angle (CPA), defined as the angle between the long axis of the tibia and the long axis of the femur projected onto the tibial coronal plane to simulate a 2D videographic analysis. We then simulated how changing the position of the camera relative to the participant would affect knee abduction angles.

Results:

During flexion, when CPA was calculated from a purely anterior or posterior view of the joint—an ideal scenario for measuring knee abduction from 2D videographic analysis—CPA was significantly different from VVA ( P < .0001). CPA also varied substantially with the position of the camera relative to the participant.

Conclusion:

How closely CPA (derived from 2D videographic analysis) relates to VVA (derived from a 3D anatomic coordinate system) depends on FLA and camera orientation.

Clinical Relevance:

This study provides a novel comparison of knee abduction angles measured from 2D videographic analysis and those measured within a 3D anatomic coordinate system. Consideration of these findings is important when interpreting 2D videographic data regarding knee abduction angle in ACL injury.
Lumbar Spine Injuries in National Collegiate Athletic Association Athletes: A 5-Season Epidemiological Study
Authors: Hassebrock Jeffrey D. , Patel Karan A. , Makovicka Justin L. , Chung Andrew S. , Tummala Sailesh V. , Peña Austin J. , Williams Kyle E. , Hartigan David E. , Chhabra Anikar
Published: January 2019

Background:

Lumbar spine injuries in National Collegiate Athletic Association (NCAA) athletes have not been well studied.

Purpose:

To describe the epidemiology of lumbar spine injuries in NCAA athletes during the 2009/2010 through 2013/2014 academic years utilizing the NCAA Injury Surveillance Program (ISP).

Study Design:

Descriptive epidemiology study.

Methods:

A voluntary convenience sample of NCAA varsity teams from 25 sports was examined. Mechanism of injury, injury recurrence, and time lost from sport were recorded. Injury rates were calculated as the number of injuries divided by the total number of athlete-exposures (AEs). AEs were defined as any student participation in 1 NCAA-sanctioned practice or competition. Injury rate ratios and injury proportion ratios were calculated to compare the rates within and between sports by event type, season, patient sex, mechanism, injury recurrence, and time lost from sport. Comparisons between sexes were made utilizing data that had both male and female samples.

Results:

An estimated 50,834 lumbar spine injuries were identified. The overall rate of injuries was 2.88 per 10,000 AEs. The rate of injuries was 2.60 per 10,000 AEs in men compared with 2.89 per 10,000 AEs in women for sex-comparable sports. Women were 1.11 times more likely than men to suffer a lumbar spine injury. Women's gymnastics (8.02 injuries per 10,000 AEs) and women's tennis (5.73 injuries per 10,000 AEs) had the highest rates of lumbar spine injuries. Athletes were 1.6 and 2.4 times more likely to sustain a lumbar spine injury during the preseason than the regular season or postseason, respectively. Noncontact was the most common mechanism of injury (45%). Injury recurrence was most common in men’s outdoor track (43%). Most injuries resulted in less than 24 hours of time loss from event participation (64%).

Conclusion:

The rate of lumbar spine injuries was high in NCAA athletes, and injuries commonly recurred (20.73%). In general, women were more likely to sustain a lumbar spine injury compared with men. Higher injury rates occurred during competition and via a noncontact mechanism of injury. In addition to prevention programs, reconditioning programs should be considered to prevent these injuries.
Rethinking Addiction
Authors: Ewald D. Rose , Strack Robert W. , Orsini Muhsin Michael
Published: January 2019

Addiction is a complex and challenging condition with many contributing factors. Although addictive behaviors appear to be individual choices, behavior alterations cannot be addressed successfully without considering characteristics of the physical and social environments in which individuals live, work, and play. Exposure to chronic psychosocial stressors and the physiological response of individuals to their external environment activates the brain’s neuroendocrine hypothalamic-pituitary-adrenal axis, with profound conditioning effects on behavior. This brief synopsis describes the social determinants of health; examines the interconnectedness of the psychosocial environment, behavior, and subsequent health outcomes; discusses the environment’s critical influence on brain plasticity, adaptation and functioning; and explores additional factors that complicate adolescent addiction. Because the environment is both a determinant of behavior and an opportunity for intervention, in the context of addictions, it is important to incorporate these factors in the analysis of risk and design of early interventions for prevention and amelioration of addiction.
Use of the Strengths and Difficulties Questionnaire to identify treatment needs in looked-after children referred to CAMHS
Authors: Wright Hannah , Wellsted David , Gratton Jacqui , Besser Sarah Jane , Midgley Nick
Published: January 2019

Background:

In England and Wales, the single-informant Strengths and Difficulties Questionnaire (SDQ) is used to assess and monitor looked-after children’s (LAC) mental health; and some targeted Child and Adolescent Mental Health Services (CAMHS) include a minimum SDQ score in their acceptance criteria. However, its ability to identify LAC who need mental health treatment is insufficiently understood.

Methods:

One hundred and forty four LAC referrals to a Targeted CAMHS Team were screened as part of a larger study. To establish how well the SDQ identified children who required treatment, Total Difficulties Scores from single-informant SDQs submitted at referral were compared to treatment recommendations following routine CAMHS assessment in a real-world setting. To explain the results, clinicians ( n = 9) from the team were interviewed and key themes identified using thematic analysis.

Results:

AUROC analysis found that the single-informant SDQ discriminated between children who were assessed as needing a mental health intervention and those who did not with low accuracy when SDQs were completed by carers or young people themselves, and moderate accuracy for teacher-completed SDQs. Optimal cutoff scores are calculated and are lower than advised in scoring guidance. Key themes from clinician interviews identified possible gaps and limitations: Developmental trauma and attachment difficulties, A different kind of patient?, Seeing the “bad” but neglecting the sad, and The importance of clinical judgment.

Conclusions:

Contrary to current UK Government policy, this study suggests that the single-report SDQ should not be relied upon as a sole means of identifying mental health difficulties in this vulnerable, high-risk population.
Investigations on thin SS sheets joining by pulsed micro-plasma transferred arc process
Authors: Chaudhary Jigar , Jain Neelesh Kumar , Pathak Sunil , Koria S. C.
Published: January 2019

Joining of thin sheets is challenging due to difficulty in maintaining localized melting and solidification. This becomes more difficult while thin sheet joining of stainless steel due to its poor weld/joining properties. This article reports on autogenous joining of 0.4 mm thickness sheets of 316L austenitic stainless steel (SS) using pulsed micro-plasma transferred arc (P-µPTA) process. Decision of using autogenous joining was taken on the basis of observations of experimentation on homogenous joining of SS thin sheets using 0.274 mm diameter SS filler wire. Effects of pulse-on time, pulse-off time, peak current and torch travel speed on the joint strength of weld were investigated with an objective to identify the optimum values for the maximum tensile strength of the joint. It was found that 50% duty cycle, 10% pulse frequency, 3.5 A peak current and torch travel speed 250 mm/min yielded maximum joint strength 553 MPa. The fusion zone was found to have finer grain size. Non-existence of heat-affected zone absence was assured by very minor dissimilarity in the values of microhardness over the fusion zone. This study establishes the capability of pulse micro-plasma transferred arc process for joining thin sheets of stainless steel without any filler material and producing very good quality joint with very insignificant heat-affected zone (HAZ), thermal distortion and porosity using much less power as compared to conventional fusion joining processes.
Genetic predisposition to MDS: clinical features and clonal evolution
Authors: Kennedy Alyssa L. , Shimamura Akiko
Published: January 2019

Myelodysplastic syndrome (MDS) typically presents in older adults with the acquisition of age-related somatic mutations, whereas MDS presenting in children and younger adults is more frequently associated with germline genetic predisposition. Germline predisposition is increasingly recognized in MDS presenting at older ages as well. Although each individual genetic disorder is rare, as a group, the genetic MDS disorders account for a significant subset of MDS in children and young adults. Because many patients lack overt syndromic features, genetic testing plays an important role in the diagnostic evaluation. This review provides an overview of syndromes associated with genetic predisposition to MDS, discusses implications for clinical evaluation and management, and explores scientific insights gleaned from the study of MDS predisposition syndromes. The effects of germline genetic context on the selective pressures driving somatic clonal evolution are explored. Elucidation of the molecular and genetic pathways driving clonal evolution may inform surveillance and risk stratification, and may lead to the development of novel therapeutic strategies.
Statistical methods to enable practical on-site tomographic imaging of whole-core samples
Authors: Mendoza Alberto , Roininen Lassi , Girolami Mark , Heikkinen Jere , Haario Heikki
Published: January 2019

Statistical methods enable the use of portable industrial scanners with sparse measurements, suitable for fast on-site whole-core X-ray computed tomography (CT), as opposed to conventional (medical) devices that use dense measurements. This approach accelerates an informed first-stage general assessment of core samples. To that end, this novel industrial tomographic measurement principle is feasible for rock-sample imaging, in conjunction with suitable forms of priors in Bayesian inversion algorithms. Gaussian, Cauchy, and total variation priors yield different inversion characteristics for similar material combinations. An evaluation of the inversion performance in rock samples considers, in a discrete form, conditional mean estimators, via Markov Chain Monte Carlo algorithms with noise-contaminated measurements. Additionally, further assessment indicates that this statistical approach better characterizes the attenuation contrast of rock materials, compared with simultaneous iterative reconstruction techniques. Benchmarking includes X-ray CT from numerical simulations of synthetic and measurement-based whole-core samples. To this end, we consider tomographic measurements of fine- to medium-grained sandstone core samples, with igneous-rich pebbles from the Miocene, off the Shimokita Peninsula in Japan, and fractured welded tuff from Big Bend National Park, Texas. Bayesian inversion results confirm that with only 16 radiograms, natural fractures with aperture of less than 2 mm wide are detectable. Additionally, reconstructed images found approximately spherical concretions of 6 mm diameter. To achieve similar results, filtered back projection techniques require hundreds of radiograms, only possible with conventional laboratory scanners.
Applications of the trend-match attribute for interpreting seismic velocity data
Authors: Chen Mingya , O’Grady Damian
Published: January 2019

A seismic velocity model is one of the products generated from a seismic imaging project. Recent advances in velocity modeling techniques have significantly improved the quality of seismic velocity data. Yet, the use of seismic velocity to guide geologic interpretations is still limited. This is mainly due to the overwhelming effect of compaction and the low-resolution nature of the seismic velocity model. Geologic boundaries and anomalies are often difficult to visualize from seismic velocity data alone. A new attribute called the trend-match attribute is proposed to reveal changes in velocity compaction trends from seismic velocity. The attribute is computed by comparing seismic velocity data with the regional velocity depth trends defined for different lithofacies using wells. We applied the trend-match attribute on several case studies to facilitate stratigraphic interpretation, horizon mapping, and erosion thickness estimation. Integration of the trend-match attribute volume with migrated seismic images can further constrain the geologic and stratigraphic interpretation at a regional scale.
Addition of Chemotherapy Is Associated With Decreased Survival in Early-Stage (T1-2N0M0) Glottic Squamous Cell Carcinoma Treated With Definitive Radiotherapy
Authors: Wang Chenyang , Kishan Amar U. , Raldow Ann , Beron Philip , Wong Deborah J. , St John Maie , Steinberg Michael L. , Chin Robert
Published: January 2019

Purpose

The role of chemoradiation (CRT) in treating patients with early-stage glottic squamous cell carcinoma (SCC), especially for T2N0M0 glottic SCC with impaired vocal cord mobility, remains unexplored. We sought to evaluate the impact of CRT on survival in early-stage glottic SCC by using the SEER database.

Patients and Methods

We included patients with localized (T1-4N0M0) glottic SCC (N = 4,743) diagnosed between 2004 and 2014 and treated with definitive radiotherapy (RT) alone, CRT, or laryngectomy alone in the SEER database. Disease-specific mortality (DSM) was evaluated via multivariable regression using a competing risk model that accounts for other-cause mortality as a competing risk event for DSM. One-to-one propensity score matching between CRT and RT cohorts was also performed to facilitate comparison of cumulative DSM and other-cause mortality incidences stratified by T stage.

Results

After stratification by T stage, CRT was associated with increased DSM in T1-2N0M0 glottic SCC (adjusted hazard ratios [AHRs], 4.222 and 2.260 for T1 and T2 disease, respectively; P < .001 for both). For T2N0M0 glottic SCC with and without impaired vocal cord mobility, CRT resulted in significantly increased DSM compared with RT alone in both cohorts (AHR, 2.084; P = .046 and AHR, 2.412; P < .001, respectively). After propensity score matching, cumulative incidence plots demonstrated a statistically significant increase in DSM associated with CRT compared with RT alone for both T1 and T2 glottic SCC ( P < .001 and P = .003, respectively).

Conclusion

CRT for T1-2N0M0 glottic SCC was associated with increased DSM compared with RT alone. This pattern persisted upon further stratification on the basis of vocal cord mobility status for T2N0M0 glottic SCC. This finding warrants careful consideration of chemotherapy in early-stage glottic SCC.
Joint moments during sprinting in unilateral transfemoral amputees wearing running-specific prostheses
Authors: Namiki Yuta , Hashizume Satoru , Murai Akihiko , Kobayashi Yoshiyuki , Takemura Hiroshi , Hobara Hiroaki
Published: January 2019

Knowledge of joint moments will provide greater insight into the manner in which lower-extremity amputees wearing running-specific prostheses regain running capacity and compensate for replacement of an active leg with a passive prosthetic implement. Thus, the purpose of this study was to investigate three-dimensional joint moments during sprinting for unilateral transfemoral amputees wearing running-specific prostheses. Ten sprinters with unilateral transfemoral amputation performed maximal sprinting at the 22-m mark while wearing running-specific prostheses. Joint moments were calculated through an inverse dynamics approach. All peak flexion and extension moments in the prosthetic leg were found to be lower than those of the intact leg, except for the peak plantar flexion moment. In the frontal plane, the peak adduction and abduction moments in the prosthetic leg were generally lower than those of the intact leg. The peak internal rotation moments differed significantly between the legs, but the peak external rotation moments did not. The results of the present study suggest that asymmetric joint moment adaptations occur for unilateral transfemoral amputees to compensate for replacement of the biological leg with a passive prosthetic knee joint and running-specific prosthesis.
Assembly and early maturation of large subunit precursors
Authors: Chaker-Margot Malik , Klinge Sebastian
Published: January 2019

The eukaryotic ribosome is assembled through a complex process involving more than 200 factors. As preribosomal RNA is transcribed, assembly factors bind the nascent pre-rRNA and guide its correct folding, modification, and cleavage. While these early events in the assembly of the small ribosomal subunit have been relatively well characterized, assembly of the large subunit precursors, or pre-60S, is less well understood. Recent structures of nucleolar intermediates of large subunit assembly have shed light on the role of many early large subunit assembly factors, but how these particles emerge is still unknown. Here, we use the expression and purification of truncated pre-rRNAs to examine the initial assembly of pre-60S particles. Using this approach, we can recapitulate the early recruitment of large subunit assembly factors mainly to the domains I, II, and VI of the assembling 25S rRNA.
Improving energy efficiency of electrochemical blackwater disinfection through sequential reduction of suspended solids and chemical oxygen demand
Authors: Hawkins Brian T. , Rogers Tate W. , Davey Christopher J. , Stoner Mikayla H. , McAdam Ewan J. , Stoner Brian R.
Published: January 2019

Onsite reuse of blackwater requires removal of considerable amounts of suspended solids and organic material in addition to inactivation of pathogens. Previously, we showed that electrochemical treatment could be used for effective pathogen inactivation in blackwater, but was inadequate to remove solids and organics to emerging industry standards. Further, we found that as solids and organics accumulate with repeated recycling, electrochemical treatment becomes less energetically sustainable. Here, we describe a pilot study in which concentrated blackwater is pretreated with ultrafiltration and granular activated carbon prior to electrochemical disinfection, and show that this combination of treatments removes 75-99% of chemical oxygen demand, 92-100% of total suspended solids, and improves the energy efficiency of electrochemical blackwater treatment by an order of magnitude.
Automated verbal autopsy classification: using one-against-all ensemble method and Naïve Bayes classifier
Authors: Murtaza Syed Shariyar , Kolpak Patrycja , Bener Ayse , Jha Prabhat
Published: January 2019

Verbal autopsy (VA) deals with post-mortem surveys about deaths, mostly in low and middle income countries, where the majority of deaths occur at home rather than a hospital, for retrospective assignment of causes of death (COD) and subsequently evidence-based health system strengthening. Automated algorithms for VA COD assignment have been developed and their performance has been assessed against physician and clinical diagnoses. Since the performance of automated classification methods remains low, we aimed to enhance the Naïve Bayes Classifier (NBC) algorithm to produce better ranked COD classifications on 26,766 deaths from four globally diverse VA datasets compared to some of the leading VA classification methods, namely Tariff, InterVA-4, InSilicoVA and NBC. We used a different strategy, by training multiple NBC algorithms using the one-against-all approach (OAA-NBC). To compare performance, we computed the cumulative cause-specific mortality fraction (CSMF) accuracies for population-level agreement from rank one to five COD classifications. To assess individual-level COD assignments, cumulative partially-chance corrected concordance (PCCC) and sensitivity was measured for up to five ranked classifications. Overall results show that OAA-NBC consistently assigns CODs that are the most alike physician and clinical COD assignments compared to some of the leading algorithms based on the cumulative CSMF accuracy, PCCC and sensitivity scores. The results demonstrate that our approach improves the performance of classification (sensitivity) by between 6% and 8% compared with other VA algorithms. Population-level agreements for OAA-NBC and NBC were found to be similar or higher than the other algorithms used in the experiments. Although OAA-NBC still requires improvement for individual-level COD assignment, the one-against-all approach improved its ability to assign CODs that more closely resemble physician or clinical COD classifications compared to some of the other leading VA classifiers.
El nexo entre migración, seguridad y derechos humanos en la política migratoria de Argentina (1990-2015)
Authors: Pereira Andrés
Published: January 2019

Uno de los cambios más relevantes en la forma en que son comprendidas y tratadas las migraciones internacionales, en particular la “inmigración limítrofe”, en el marco de las políticas migratorias en Argentina es la adopción de discursos, prácticas y políticas humanitarias a través de las que se reformulan las maneras en que los migrantes son construidos como una cuestión vinculada a la seguridad. Sujetos considerados como víctimas/vulnerables, a los cuales hay que proteger y garantizar sus derechos humanos, e convierten en imágenes cada vez más usuales y estas conviven al mismo tiempo con formas de comprender las migraciones como una amenaza o riesgo para la seguridad. Por ello, el presente artículo tiene como objetivo comprender el nexo entre migración, seguridad y derechos humanos que se ha desarrollado en el campo de las políticas migratorias de Argentina en el período 1990-2015, analizando los discursos y prácticas de los actores relevantes en el campo de las políticas migratorias.
From staff nurse to nurse consultant: Continuing professional development part 9: support and finance
Authors: Fowler John
Published: January 2019

John Fowler, Educational Consultant, explores CPD for clinically based nurses
Supporting better adherence among patients engaged in intermittent self-catherisation
Authors: Nørager Rune , Bøgebjerg Claus , Plate Iben , Lemaitre Stephanie
Published: January 2019

Coloplast has conducted a qualitative study among health professionals working in the field of continence care. Interviews with health professionals working in urology and rehabilitation provided insights into the barriers to, and supporters of, adherent behaviour—suggesting ways in which health professionals can work with patients performing intermittent self-catheterisation (ISC) to support better adherence. This includes individualised training that addresses individual fears, ensures correct understanding of the body and the treatment, and eliminates misconceptions. They can also help patients set realistic ambitions, and give them practical advice that will help them adapt ISC to their daily life. Patients need to know how to handle urinary tract infections, how to cope with contradictory instructions from other sources, and how to identify support resources and accurate information. Specific challenges relating to support for urology patients and rehabilitation patients were also highlighted.
Paediatric nurses' adoption of aseptic non-touch technique
Authors: Isaac Rachel , Einion Alys B , Griffiths T Howard
Published: January 2019

Background:

in 2015, NHS Wales introduced a national standardised approach to aseptic non-touch technique (ANTT). This approach aims to standardise practice and promote better clinical outcomes.

Aim:

to provide insight into the challenges faced by clinical staff adopting ANTT during intravenous therapy.

Methods:

focused ethnography across two paediatric wards in NHS Wales. Data collection included participant observation, audit questionnaires and semi-structured interviews. Data were analysed according to Wolcott's (1994) process and emerging themes were reflected upon against the theoretical framework of Kirkpatrick's (1994) model of training evaluation.

Findings:

absence of feedback following training, individual preference, lack of opportunity to practise the ANTT technique, lack of clarity and standardisation and expectations of parents/medical staff are all challenges faced by registered nurses.

Implications of the study:

the findings may be used by NHS managers to support national initiatives within staff training and development programmes, and to improve infection prevention initiatives. Organisational culture is a modifier of healthcare worker behaviour and requires further attention locally and nationally. Quality assurance in the adoption of standardised best practice must take into account staff training and development needs, and workplace culture.
Clinical experience of a subcutaneously anchored sutureless system for securing central venous catheters
Authors: Pittiruti Mauro , Scoppettuolo Giancarlo , Dolcetti Laura , Celentano Davide , Emoli Alessandro , Marche Bruno , Musarò Andrea
Published: January 2019

This article reports the results of three prospective clinical studies conducted in a university hospital regarding the efficacy, safety and cost effectiveness of a subcutaneously anchored sutureless system for securing central venous catheters. The results were favourable to the adoption of such a device, and the analysis of the data allowed the authors to define those categories of patients where the device should have the most benefit: neonates, children, non-compliant older patients with cognitive difficulties, patients with skin abnormalities that may reduce the effectiveness of a skin-adhesive sutureless securement system, patients who are candidates for having a peripherally inserted central catheter (PICC) in place for more than 8 weeks, and any other category of patients with a recognised high risk of catheter dislodgement.
Chronic idiopathic pain following implant placement in the anterior maxilla: a case series
Authors: Patel Jaymit , Nixon Peter
Published: January 2019

Abstract: This article reports on three patients who presented with pain following placement of dental implants in the anterior maxilla. It aims to document a rare complication of implant placement which arguably requires further investigation through characterization of cases. Three cases in total were identified and the literature review identified only one previous case series. All three cases were characterized by idiopathic pain which presented, in some cases, in a delayed fashion following fixture placement. All cases failed to resolve following treatment. Persistent chronic idiopathic pain is a recently described risk of dental implant placement. This case series highlights the need for careful case selection and informed consent, particularly when considering changing paradigms relating to consent procedures.

CPD/Clinical Relevance: This case series aims to raise awareness for this rare complication of implant placement in the anterior maxilla. It highlights the importance of thorough pre-surgical investigation, planning and consent.
Principles of orthognathic management of dentofacial discrepancies
Authors: Achal Kulraj S , Naini Farhad B , Gill Daljit S
Published: January 2019

Abstract: Individuals with severe dentofacial discrepancies that are beyond the scope of conventional orthodontic treatment will often require a joint orthodontic-surgical approach to manage their malocclusion. This treatment approach involving orthodontics in combination with orthognathic surgery is used to manage severe underlying skeletal discrepancies in the anterior-posterior (AP), vertical and transverse dimensions. The purpose of this article is to highlight the principles of orthognathic treatment. The general dental practitioner (GDP) plays an important role in maintaining dental health, especially whilst patients are on the orthognathic care pathway. Patients may also seek the advice of the GDP about the possible benefits of such a treatment approach before deciding to embark upon treatment.

CPD/Clinical Relevance: It is important for GDPs to understand the principles of orthognathic management in order to support their patients through treatment.
Clinical and subclinical ketosis in dairy cattle
Authors: Manning Al
Published: January 2019

Much has been written about ketosis in dairy cattle, and its association with post-partum disease. This article sets out where we are now with ketosis and what the future of testing, prevention and monitoring might look like.
Babesiosis in the UK and approach to treatment
Authors: Jerram Lucy , Willshire Jim
Published: January 2019

Babesiosis is a vector-borne disease of cattle which, in the UK, is caused by two species — Babesia divergens and Babesia major. Disease is sporadically seen in western Britain with a peak in the spring and another in the autumn. The most recognisable clinical sign is haemoglobinuria which gives babesiosis the colloquial name of ‘redwater fever’. Other clinical signs are pyrexia of 40°C, anorexia, depression, weakness, tachycardia and pipe stem diarrhoea, which progress to severe dehydration, recumbency and death in up to 21% of cases. Diagnosis is based on history, clinical signs, confirmation of anaemia and examination of stained blood smears. Treatment involves administration of imidocarb dipropionate in all cases. Blood transfusion is indicated in cattle with a packed cell volume of less than 15%. Prevention is challenging in naïve adults as there is no commercially available vaccination; exposing youngstock to ticks should ensure natural immunity is acquired.
CattleReview
Authors: Barrett David C
Published: January 2019

Introduction:

This edition of Cattle Review considers papers on the use of recently developed technology to monitor rumen health, the aetiology of digital dermatitis and the on-farm storage of medicines on dairy farms. Highlighting also an initiative to promote veterinary surgeons and farmers working together to remove inappropriate medicines from farm medicine stores.
Donkey and mule behaviour for the veterinary team
Authors: Haines Anna , Goliszek Joanna
Published: January 2019

The donkey's evolution, ethology and learning capacity mean that the behaviour of donkeys and mules is significantly different to that of the horse. Subtle behaviour change in the donkey can indicate severe, life-threatening disease. An understanding of donkey and mule behaviour will help veterinary surgeons to handle these animals safely, treat them effectively and educate owners to spot the subtle signs of disease.
This is not about you it’s about us or at the very least me
Authors: Benivolski Xenia
Published: January 2019

This text meanders, like a snaking river, through topics such as migration, land use, phonetics, naming, and animal symbology, to produce a constellation of thought around the letter S.
The Cut of the Generic: An Interview with Jodi Dean
Authors: Litwack Michael , Dean Jodi
Published: January 2019

The acclaimed political philosopher and media theorist Jodi Dean is the author of numerous monographs, including Crowds and Party, The Communist Horizon, Blog Theory, and Democracy and Other Neoliberal Fantasies. Taking her most recent work on the theory of the comrade as its point of departure, this interview addresses Dean’s critique of enclosure and the individual form; the politics of genericity and fungibility; the limits of post-representationalism; and the futures of the political in an age of anthropogenic climate change.
Untitled
Authors: Ersmark Åsa
Published: January 2019

In our culture, women are pressured, by conventions of decorum and supposed hygiene to conceal any sign of their menstruation, and yet what a common and inescapable visual presence this blood is in women’s lives. Fungi, which bloom out of the charred remains of burnt-out forests, remind us that change occurs in cycles. Ersmark engages cyclical temporality and the ambiguous visual status of menstruation, to render mushrooms that appear at ephemeral, but which endure and proliferate. The paintings’ psychedelic permanence remains — like stains on a mattress.
Jade Windscreen Powder: Sympoietic Tissue Sludge Compostition
Authors: Kang Laurie , Melia Tiziana La
Published: January 2019

Jade Windscreen Powder: w Tissue Sludge Compostition

A collaborative project between Kang and La Melia, Jade Windscreen Powder: w Tissue Sludge Compostition results from a shared interest in screens and netting, which each has explored previously in their own, individual artistic practices. This text, part of an ongoing series of e-mails, takes the form of a fictional, expansive conversation between Tick and Laver, a pest and a weed, respectively. It begins at the edge of a forest and moves between a garden, an art gallery, a memory, Surrey BC, a daydream; environs are provisional and fleeting while identities shift in voice and shape. The artists glean from a wide-cast net of references, from science and technology studies, to poetry, to queer theory, to personal stories and fantasies. The initial objects, the screen and net, become a permeable membrane, an ultra-sensitive space or container, becoming with that which it contains. Encounter becomes shape with a name.
Serological profiling of rabies antibodies by enzyme-linked immunosorbent assay and its comparative analysis with rapid fluorescent focus inhibition test in mouse model
Authors: Debnath Ashis , Pathak Dinesh C. , Ramamurthy Narayan , Mohd Gulam , Pandey A. B. , Upmanyu Vikramaditya , Tiwari A. K. , Saravanan R. , Chellappa Madhan Mohan , Dey Sohini
Published: January 2019

Aim: In this study, we have used enzyme-linked immunosorbent assay (ELISA) as an alternative test to replace the cumbersome rapid fluorescent focus inhibition test (RFFIT) to ascertain the immune status of immunized mice against rabies virus.

Materials and Methods: Rabies is a devastating disease worldwide caused by rabies virus. Proper usage of pre- or post-exposure rabies vaccine can prevent the disease transmission. In this study, mice were immunized with Vero cell-adapted inactivated rabies vaccine. RFFIT was used as a test to determine the serum neutralizing titers in infected/vaccinated mice. Seroprofiling of mice sera was done in vitro by ELISA.

Results: Twenty-one days post-immunization, both ELISA and RFFIT assays indicated similar antibody levels in mice sera that were immunized with Vero cell-adapted inactivated rabies vaccine. Both the tests were correlated, and the linearity was verified by the regression line (R2=0.979).

Conclusion: In this study, we profiled the serological status of Vero cell-adapted inactivated rabies vaccine through ELISA in mice model that correlated well with the OIE gold standard test RFFIT.
Molecular evidence of Ehrlichia canis and Anaplasma platys and the association of infections with hematological responses in naturally infected dogs in Kalasin, Thailand
Authors: Piratae Supawadee , Senawong Priyakorn , Chalermchat Pornchalerm , Harnarsa Warissara , Sae-chue Benjawan
Published: January 2019

Background: Tick-borne bacteria, Anaplasma platys and Ehrlichia canis are well recognized as the etiology of anemia and thrombocytopenia in dogs. The clinical signs of anaplasmosis and ehrlichiosis range from asymptomatic to severe symptoms. There are insufficient studies about epidemiological surveys of these blood parasites, also the association of infections with the hematological study. Aim: This study aimed to screen A. platys and E. canis in naturally infected dogs and the effects of the infection on the levels of packed cell volume (PCV) and platelet count. Materials and Methods: A total of 68 blood samples were collected from free-roaming dogs at Nong Kung Sri district, Kalasin Province, Thailand, and examined for A. platys and E. canis infection by polymerase chain reaction (PCR) and measured PCV levels and platelet count. Results: Using nested PCR, 42.65% of dogs were infected with one or two pathogens. The molecular detection of anaplasmosis and ehrlichiosis in this population was 29.4% (95% confidence interval [CI]: 18.98-41.71) and 25% (95% CI: 14.4-35.3), respectively. Coinfection occurred at 11.8% (95% CI: 5.22-21.87). Infection with E. canis and coinfection showed significant association with PCV levels (p<0.05) while A. platys infection showed no statistical relationship. Infection with A. platys, E. canis, and coinfection had a non-significant correlation with platelet count (p>0.05). Conclusion: This study provides data of anaplasmosis and ehrlichiosis in free-roaming dogs which indicated that these zoonotic diseases are widespread and require for disease frequency determination, especially in Kalasin Province of Thailand where data of tick-borne infections in dogs have not been reported.
Regionalizmusok Szabó Magda Szüret című elbeszélő költeményében
Authors: Parapatics Andrea
Published: January 2019

A tanulmány Szabó Magda kevéssé ismert elbeszélő költeményével, a Szürettel foglalkozik, azon belül is nyelvezetének regionális jegyeit vizsgálja. A mű a II. világháború utolsó hónapjait örökíti meg, különös hangsúlyt fektetve a szülőváros elhagyása, illetve feldúlása miatt érzett tragédiaélményre. A debreceniségét szinte minden művében, megnyilatkozásában holtáig hirdető író regionális identitása nemcsak sorainak tartalmából, hanem nyelvezetéből is kitűnik: a tanulmány több tucat olyan adatot közöl a Szüretből a dialektológiai szakirodalomra hivatkozva, amely az északkeleti nyelvjárási régió szabolcs-szatmári csoportjának hangtani, alaktani vagy szókészlettani sajátossága. Az elemzésből az is világosan kiderül, hogy a szerző a regionalizmusokat nem csupán a mű szereplőinek a szájába adja, hanem a történésekben E/1. személyben részt vevő elbeszélőt is legalább akkora mértékben jellemzik. „Szabó Magda jó tanárnő” (Esterházy, 1997/2003: l. n.), aki a lokális identitás vállalása terén is példaértékű lehet egy olyan beszélőközösség számára, ahol a területi alapon különböző nyelvi formulák napjainkban is sok esetben megbélyegzettek, holott a nyelvi sokszínűség elismerése már évek óta kiemelt szerepet kap a magyar Nemzeti alaptantervben is. Mivel a Szabó Magda munkásságával való ismerkedés az általános és középiskolai irodalom tananyag szerves része, jelen tanulmányban vizsgált nyelvjárási hátterének említése a nyelvi változatosság témakörének a tanításához is élményszerű segítségként szolgálhat.
Analysis of QOS VLAN Based on Djikstra’s Algorithm on Open Shortest Path First(OSPF)
Authors: Alfani Muhammad Nur , Sugiantoro Bambang
Published: January 2019

As an institution engaged in SMK Muhammadiyah 03 Yogyakarta  requires network infrastructure as a medium of communication. Infrastructure in SMK Muhammadiyah based VLAN but still using static routing and star topologies as a medium of communication between router. This leads to the main router performance overburdened  which makes the network infrastructure down. It is necessary to reform the network, especially in the communication protocol on the router by using protocol Open Shortest Path First(OSPF). OSPF is a link state-based routing protocol that uses Dijkstra’s algorithm to find the best path is taken as a communication medium. Makin paths made by considering various aspects of the parameters that affect network traffic. OSPF can minimize down on network infrastructure caused by the buren of a huge traffic to maintain the stability of traffic on communication lines. The results using the method QOS on infrastructure with the OSPF protocol can be classified very nice. It is obtaine from the measurement parameter delay <150 ms, packet loss (0%), an bandwidth has a very goo category based on the standard TIPHON. From the results of the QOS parameters also obtained a decrease in delay value by 31% on infrastructure with the OSPF protocol. This proves that the network traffic is more stable when using OSPF protocol.
Analysis Of Quality Of Service (Qos) Youtube Streaming Video Service In Wireless Network In The Environment Faculty Of Science And Technology Uin Sunan Kalijaga
Authors: Wishnu Asep , Sugiantoro Bambang
Published: January 2019

The growing number of internet users in Indonesia, making the number of users increasing especially video streaming on Youtube service. This increase is based on rapid technological developments, especially PCs, Laptops and Smartphones that use wireless or wireless internet access. The use of streaming video over wireless networks is different from cable networks Because The characteristics of wireless networks are limited Compared to wired networks, and the characteristics of streaming video transmissions that require different handling than traditional text, and the data transmissions. As a first step towards Achieving an optimum Internet network service effort, Applies Action Research This research method by utilizing video quality with 360p, 480p, and 720p. The QOS parameters Analyzed Consist of delay, jitter, throughput, packet loss and bandwidth using wireshark and NetTools for the testing phase. The results of analysis using QoS for streaming video shows the performance of wireless network services at UIN Sunan Kalijaga, Faculty of Science and Technology is still not maximal especially on video with 480p quality, that has a 20 ms delay and jitter quality level ms According -0.0269 to TIPHON is very good. The amount of throughput is 0:55 MBps throughput and the percentage is 3% and the packet loss value is 28%, if it is Categorized by TIPHON standardization bad this value falls into the category. For the average bandwidth used is 329 714 bps value.
VLAN-based LAN Network Management Comparison using Cisco and Brocade
Authors: Gatra Ramadhan , Akbar Reonaldo , Sugiantoro Bambang , Asyhab Naufal
Published: January 2019

Abstract— The need for security and convenience in carrying out data requires all users to be able to create a safer network, both in terms of data communication and in terms of sharing internet connection lines. The effectiveness of performance in work is always required to be able to work quickly and on time without the constraints of one of the high data traffic that causes problems in network devices in one building. Which ultimately causes all work to be hampered in its completion. With the management of VLANs in a LAN connection, it will be able to parse problems especially in terms of data communication and logical data transmission. (Abstract)Keywords: LAN, VLAN, Network
FUNGSI TERDEKATI DAN SIFAT-SIFATNYA
Authors: Aziz Abdul , Hariyanto Susilo , Sumanto Y.D. , Solikhin Solikhin
Published: January 2019

In this paper, we have defined an approachable function using a simple function on a compact sets. Furthermore the simple properties of the function was examined and it was obtained that measurable function, continuous function, and bounded function are approachable function along the function space is a linier space.
IMPLEMENTASI LOGIKA FUZZY MAMDANI UNTUK MENENTUKAN KOMPOSISI OPTIMAL PUPUK ORGANIK DAN ANORGANIK NPK PADA TANAMAN MENTIMUN
Authors: Analistyawan Fajar Ridwan , Sutrisno Sutrisno , Zaki Solichin
Published: January 2019

In this article, we have determined the optimal composition of organic fertilizer and NPK inorganic fertilizer for cucumber plants. We have formulated two fuzzy systems which are fuzzy system 1 and fuzzy system 2. The inputs for fuzzy system 1 are plants’ height and the number of leaves where the output is the growth rate. Fuzzy system 2 had input of growth rate and NPK concentration and output of organic fertilizer concentration. By processing the data using fuzzy system, we have compared the cucumber plant with organic fertilizer and NPK to cucumber plant that was used only NPK fertilizer. The result had shown that the cucumber plant with organic fertilizer and NPK was produced the better outcome than the cucumber plants with NPK only.
Lectotypification of the basionym and a synonym of Givotia moluccana (Euphorbiaceae) ensuring its unambiguous use
Authors: Chakrabarty T , Krishna G
Published: January 2019

A second-step lectotype is designated for the Linnaean name Croton moluccanus ensuring its unambiguous use as Givotia moluccana (L.) Sreem., for a species treated in most of the Indian and Ceylonese Floras as Givotia rottleriformis Griff. ex Wight. A lectotype is also designated for the synonym G. rottleriformis as the earlier lectotypification of this name was not based on the original material used for describing the species.
Organic Molecules in the Icy Bodies of Planetary Systems – Accepted Notions and New Ideas
Authors: Simonia Irakli , Cruikshank Dale P.
Published: January 2019

Cometary bodies are acknowledged to contain some of the most pristine matter in the Solar System, including ices and minerals. Certain number of previously unidentified spectral emission features detected in comets can be explained as emission by hydrocarbon molecules enclosed in a Shpolskii matrix and forming frozen hydrocarbon particles. UV-induced photoluminescence spectra of several self-organized molecules exhibit emission lines coincident with unidentified cometary lines, and open the possibility of the presence of this complex organic as components of the pristine organic inventory of comets. Complex organic was detected also in three satellites of Saturn. We describe in this paper results of our investigation of complex organic of the small bodies and present new approaches and hypotheses.