bluuebunny/crossref_metadata_2025 huggingface dataset:
Kandungan logam berat besi (Fe) pada air dan daging ikan lemeduk (Barbonymus schwanenfeldii) di Sungai Belumai Deli Serdang
Authors: Surbakti Nur Anisah Br , Febriani Husnarika , Syukriah Syukriah
Published: May 2024

The Belumai River is used for various societal activities as well as a disposal site for residual waste from domestic and industrial activities. One of the fishes in the Belumai River is tinfoil barb (Barbonymus schwanenfeldii). The purpose of this study is to analyze the content of iron (Fe) metals in river water and fish meat. Sampling points or stations for river water and tinfoil barb (Barbonymus schwanenfeldii) used a purposive sampling method. The content of Fe at stations I, II, and III in water also meat of tinfoil barb (Barbonymus schwanenfeldii) was 1,99 mg/L, 2,65 mg/L and 1,99 mg/L while in fish meat it was 27,02 mg/kg, 43,57 mg/kg and 88,42 mg/kg. The results of testing for Fe metal in river water and tinfoil barb’s meat (Barbonymus schwanenfeldii) have passed the water quality standard limits according to PP RI No. 22 of 2021 (0.03 mg/L) and JECFA 2020 (0.8 mg/kg). The BCF grade at station I is 13,57 L/kg, station II is 16,44 L/kg, and III is 44,37 L/kg.
Karakteristik Proksimat Tepung Daun Tarum (Indigofera zollingeriana) Hasil Fermentasi Aspergillus niger Perbandingan Air Berbeda Sebagai Bahan Baku Pakan
Authors: Panigoro Novita , Ediwarman Ediwarman , Fitria Yuliana , Karim Isnan Ibnu , Syahrizal Syahrizal , Purnama Padel
Published: May 2024

This study aims to determine the nutritional content by proximate analysis of fermented tarum leaf meal (Indigofera zollineriana) as a raw material of fish feed. The method used in this research is the experimental method using Completely Randomized Design (CRD) with 4 treatments and 3 replicates. The factor studied were the comparison of tarum leaf meal with water which consisted of 4 treatment levels, namely A (tarum leaf meal and water 1:1 w/v), B (tarum leaf meal and water 1:2 w/v), and C (tarum leaf meal and water 1:3 w/v) with 0,3% of A, niger as bioactivator and K (tarum leaf meal) as control non fermented. The fermentation period was 6 days in aerobic condition with temperature at 35-40oC. From the above research, the proximate characteristic of fermented tarum leaf meal (I. zollineriana) has a different nutritional content for each factor. The best result was B (tarum leaf meal and water 1:2 m/v) with 40.09 ± 1.874% crude protein content, 11.24 ± 0.289% fat, 7.57 ± 1.845% crude fiber, 22.61 ± 0.177% ash content, and 18,47 ± 2,347% NNFE (non nitrogen free extract).
Pertumbuhan Bibit Kakao (Theobroma cacao L.) Pada Berbagai Kombinasi Pupuk Anorganik NPK dan Pupuk Hayati Bioneensis di Polibag
Authors: Ramadhani Rizky Fajriah , Hartawan Rudi , Hayata Hayata , Marwan Edy
Published: May 2024

The cultivation of cocoa plants that began in nurseries, is an effort to increase cocoa production. High yields can be achieved with high-quality cocoa beans. This study aims to obtain a combination treatment of NPK inorganic fertilizer with the best Bioneensis bioorganic fertilizer to support the growth of cocoa seedlings. This study used a one-factor Complete Randomized Design. The treatment design tested was Bioneensis bioorganic fertilizer and NPK fertilizer with 5 levels of dosage and 3 replications. as follows:  b0 : Control, b1 : 7.5 g NPK fertilizer, b2 : 9.9 g Bioneensis fertilizer, b3 : 5 g NPK fertilizer (66.7% of b1) + 3.3 g of Bioneensis fertilizer (33.7% of b2), and b4: 2.5 g NPK fertilizer (33.7% of b1) + 6.6 g of Bioneensis fertilizer (66.7% of b2). and b4: 2.5 g NPK fertilizer (33.7% of b1) + 6.6 g of Bioneensis fertilizer (66.7% of b2). Implementation of research in the form of land preparation and shade,  preparation of planting media,  seedling preparation, feeding, treatment, and maintenance of plants. Plant height, stem diameter, header dry weight, root dry weight, root crown ratio, and quality index are the parameters that are measured. The results of this study concluded that treatment of 2.5 g of NPK fertilizer combined with 6.6 g of Bioneensis biofertilizer will increase plant height by 60.10%, rod diameter by 43.86%, The dry weight of the header was 183.31%, the dry weight of the roots was 229.41%, and the quality index was 189.20% compared to the control.
Karakteristik Kimia dan Kualitas Organoleptik Cokelat Pasta Dengan Suhu Penyangraian Yang Berbeda Menggunakan Alat Coffee Roasting
Authors: Marpaung Ridawati , Hartawan Rudi , Lesinde Simatupang Oliviandra Afrianda
Published: May 2024

The aims of this research were to determine the chemical characteristics and organoleptic quality of chocolate paste with different roasting temperatures using a coffee roasting tool. The environmental design used in this study was a Completely Randomized Design Treatment design, namely different roasting temperatures, with 4 roasting temperature levels, as follows: t1 (130oC) ; t2 (140oC); t3 (150oC );  and t4 (160oC). The duration of roasting was carried out for 30 minutes. Each treatment was repeated 3 times so that there were 12 experimental units. The variables observed in this study were chemical characteristics including water content dry cocoa beans, acidity (pH) and fat content of roasted cocoa beans, while the organoleptic qualities observed were: color, aroma, taste, bitterness, and preference for chocolate paste. The The results showed that: different roasting temperatures have a significant effect on the fat content of the roasted cocoa beans, but are not significantly different on the pH of the roasted cocoa beans : color, aroma, taste, bitterness and preference for chocolate paste. The sensory test showed that panelists  preferred aroma, preferred taste, level of bitterness was slightly bitter and level of preference was liked were 130oC-160oC.
Pengaruh Lama Penyangraian Terhadap Karateristik Kimia dan Mutu Organoleptik Pasta Cokelat
Authors: Prasetyo Muhammad Dwi , Nengsih Yulistiati , Marpaung Ridawati , Andriyani Lizyanti
Published: May 2024

Roasting is a very important post-harvest stage in processing cocoa beans into derivative products because this roasting process will produce the characteristic color, aroma, taste and texture of the cocoa beans. The research was carried out from February to March 2023 at the Basic Laboratory of Batanghari University, Jambi. The study used a completely randomized environmental design. The treatment design is roasting time with 4 levels as follows: P1: 20 minutes, P2: 30 minutes, P3: 40 minutes, P4: 50 minutes. The variables observed were the moisture content of the dry cocoa beans, the color of the chocolate paste, the aroma of the chocolate paste, the taste of the chocolate paste, the liking of the chocolate paste, the bitterness of the chocolate paste. Organoleptic testing of color, aroma, taste, brownness and liking variables was carried out using a perception test with a 5-scale Likert scale. The data was tabulated, followed by analysis of variance, then continued with the DMRT test at the α level of 5%. Based on the results of the research and discussion, it can be concluded that different roasting times have no significant effect on the acidity (pH) of roasted cocoa beans, color, aroma, taste, bitterness and liking of chocolate paste. Roasting time of 20 minutes produces chocolate paste with a brown color, a favorable aroma, a favorable taste, a slightly bitter bitterness level and a favorable level of liking.
Faktor Faktor Pendorong dan Penghambat Keinginan Petani Melakukan Peremajaan Kelapa Sawit di Desa Suka Damai Kecamatan Tebing Tinggi Kabupaten Tanjung Jabung Barat
Authors: Handayani Putri , Zainuddin Zainuddin , Wulandari Siti Abir
Published: May 2024

The purpose of this study was to analyze the factors that encourage and inhibit farmers' desire to replant oil palm trees in Suka Damai Village, Tebing Tinggi Sub-district, Tanjung Jabung Barat District. The research was conducted as a survey of farmers in Suka Damai Village with the criteria that the age of oil palm plants is more than 20 years old and technically feasible to replant. A sample of 108 farmers was taken from a population of 540 oil palm farmers using the simple random method. The research data were analyzed using a regression model with the dependent variable measured binary. The results showed that land size, number of family members, gross income from oil palm farming, and total household expenditure influenced farmers' willingness to replant. Farmer age, formal education, age of the oil palm plantation, and access to credit loans do not influence farmers' desire to replant oil palm. Factors driving farmers' desire to replant oil palm crops are variables of oil palm land area, number of farmer family members, and gross oil palm farm income, while the inhibiting factor is the total expenditure of farmer households.
Pengembangan Usahatani Tanaman Singkong di Lahan Smkn 1 Borong Kabupaten Manggarai Timur
Authors: Kaleka Marten Umbu , Coo Lea Victoria
Published: May 2024

The establishment of the cassava agribusiness business owned by SMKN 1 Borong is the result of a learning program that uses a production/service-based learning model, or factory-based learning, to educate students and prepare participants to face the world of industry and the world of work by improving their skills and competencies before students enter working world. The aim of the research is to produce recommendations for cassava cultivation guidelines in the Department of Food Crops and Horticulture at SMKN 1 Borong and to determine the feasibility of cassava farming at SMKN 1 Borong. The results of this research were reported to the Astra Education Foundation as the owner of the Borong 1 State Vocational High School transformation program into a superior vocational school. The research uses qualitative and quantitative research approaches. The method for determining the location is purposive (deliberately) by considering several things. In this research, primary data from key informants was used combined with secondary data from educational institutions and other relevant sources. The data analysis used is descriptive analysis and farming feasibility analysis which includes net present value, net B/C ratio and internal rate of return. The research results show that the requirements for cassava cultivation include planting specifications, land preparation, seed and seed preparation, land processing, planting, maintenance and harvesting. The results of the farming feasibility analysis show that the net present value is Rp. 16,862,618.58, which is more than zero, the net B/C achieved is 2.03 times greater than one, and the internal rate of return is 1.39, which is higher than bank interest of 12%. used. This means that cassava cultivation is feasible.Kata Kunci: Kelayakan; Usahatani; Singkong; Borong
İbn Rüşd’ün Bidāyetu’l-Muctehid’de Hadis Kullanımı ve Yorumu
Authors: Seven Şuayip
Published: May 2024

Hadislerin kullanımı ve yorumu, şahıstan şahsa ve ele alındıkları bağlama göre farklılık arz edebilmektedir. Bundan dolayı bir âlimin hadis kullanımı bütün eserlerinde aynı olmamış, konunun ait olduğu bilim dalı, eserlerinin hitap kitlesi ve amacına göre farklılık arz edebilmiştir. Bunun en bariz örneklerinden biri İbn Rüşd’ün (ö. 595/1198) fıkıh eserinde hadislere yaklaşımı ile felsefi/kelami eserlerinde hadislere yaklaşımı arasındaki farkta görülmektedir. İbn Rüşd felsefe ve fıkıh gibi birbirine uzak görünen iki farklı alanda eserler vermiş ve kadı-filozof kimliğini kendisinde uzlaştırmış nadir İslam düşünürlerinden biridir. Peki kadı İbn Rüşd, hadislere yaklaşımında filozof İbn Rüşd’ün felsefi nosyonundan tamamen uzaklaşmış mıdır? Kanaatimizce İbn Rüşd, fıkıh yaparken fıkhın usul ve kaidelerine bağlı kalmakla birlikte, felsefi bakış açışını imkân ölçüsünde kullanmaya gayret etmiştir. Bu, onun hükümleri akılla anlaşılan ve akılla anlaşılmayan şeklinde iki gruba ayırmasında, külli kaideleri ayet ve hadislerin anlaşılmasında kriter kabul etmesinde ve İslami hükümlerin maksatlarını iffetli, adaletli, şecaatli ve cömert olmak gibi erdemler ile (el-faḍāʾilu’l-erbaʿa) ilişkilendirmesinde görülebilmektedir. İbn Rüşd, hiç şüphesiz yüksek analitik ve sistematik düşünce kabiliyetini hadislerin seçimi ve yorumunda da gösterebilmiştir. Peki filozof ve fakih kimliğini ispat etmiş İbn Rüşd’den bir hadis âlimi olarak bahsetmek mümkün müdür? O, hadislerin yorumunda rasyonel ve makasıtçı bir yol takip etmiş midir? Maliki mezhebinin ʿAmel-i ehl-i Medīne ve mesāliḥ-i mursele metotlarına ve Hanefilerin hadis yorumlarına karşı tutumu ne olmuştur? İhtilaflı hadislerin telfîḳinde özgün çözüm yolları sunabilmiş midir? Bu çalışmada bu sorulara İbn Rüşd’ün filozof ve fakih kimliğinin hadislerin kullanım ve yorumuna olan etkisi bağlamında kendisinin Bidāyetu’l-Muctehid isimli eseri kapsamında cevaplar aranacaktır.
Ḥādis Bir Âlemden Önce Başka Âlemlerin Var Olma İmkânı, O Âlemden Önce Zamanın Varlığını Zorunlu Kılar mı? Tehāfutu’l-Felāsife’de Âlemin Kıdemi Hakkında Bir Münazaranın Mantıksal Analizi
Authors: Erken Ayşenur
Published: May 2024

Ebū Ḥāmid el-Ġazālī’nin (ö. 505/1111) Tehāfutu’l-Felāsife adlı eserinin birinci meselesi âlemin ḳıdemi hakkındadır. Bu mesele, felāsifenin âlemin ḳadīm olduğunu savunduğu dört delil ve bu delillere dair münazaradan oluşmaktadır. Zaman delili olarak adlandırdığımız ikinci delilin hususiyeti âlemin kadîm olduğu sonucuna ulaşmak için zaman kavramından yola çıkılmış olmasıdır. Tehāfutu’l-Felāsife’de, bu delilin iki ayrı şekline yer verilmektedir. Zaman delilinin ikinci şeklinde, imkân ve zaman ilişkisi gündeme gelmekte, âlemin var olma imkânına dayanarak zamanın kadîm olduğu sonucuna varılmaktadır. El-Ġazālī tarafından felāsife ile bir münazara olarak kurgulanan bu tartışmada felāsife, ḥādis bir âlemden önce başka âlemlerin var olmasının imkânının âlemden önce zamanın varlığına yol açacağını iddia etmektedir. Buna karşı el-Ġazālī, bu imkânın varlığının zamanın varlığını gerektirmediğini ileri süren muhtemel itirazları ileri sürmektedir. Bu makalede, Tehāfutu’l-Felāsife’de zaman delilinin ikinci şekline yöneltilen eleştirilerin delilin sağlamlığı konusunda şüphe oluşturacak verileri sağladığı ve delilin âlemin kıdemini ispatlama konusunda yetersiz kaldığı neticesine ulaşılmaktadır.
Diabetes Mellitus and Oral Health Status: A Case-Control Study in a Tertiary Care Hospital in Bangladesh
Authors: Lucky Jesmin Sultana , Hossain Mohammad Anayet , Mostafa Dilruba Binte , Mobashir Mohammad , Nasir Tahnia Binta , Rahman Asadur , Parvin Sadia
Published: May 2024

Introduction: Diabetes is a long-lasting, inflammation-related metabolic disorder which is diagnosed by hyperglycemia. Increased blood glucose level adversely impacts the inflammatory response to periodontium leading to more severe gingivitis and periodontitis. Therefore, periodontitis and diabetes reciprocally and adversely affect each other.
Objective: To assess and compare the oral health condition of Diabetic and non-Diabetic periodontitis patients.
Method: A non-experimental case control study was conducted among 100 diabetic and 100 non-diabetic periodontitis patients. The control group was matched by age and gender. The study was conducted for a period of ten months. A cheek list was prepared to generate the caries and CPITN index (Community Periodontal Index of Treatment Needs) index.
Result: The prevalence of dental caries scored at least one was relatively more in non-diabetics (88%) than in diabetics (65%). However, the periodontal diseases (pyorrhea) prevalence was more in diabetic periodontitis patients (97%) in compared to non-diabetics (53%). The odds ratio for CPITN Index indicated that the periodontitis patients who had diabetes were about 111.6 times (OR = 111.6, 95% CI 14.9- 832.02) more likely to have sub- gingival pocket more than 6mm in depth.
 Conclusion: Diabetes is an important health care problem. The evidence suggests that oral health care providers can have a significant, effective and positive effect on the oral and general health of patients with diabetes mellitus.
Update Dent. Coll. j: 2024; 14(1):10-14
What Do Female and Male College Students from Saudi Arabia Think of a Green Economy?
Authors: Al-Zohbi Gaydaa , A. E. Pilotti Maura
Published: May 2024

The present research surveys the views of a green economy held by Saudi Arabian college students. The economy of their country is in the process of being restructured from one largely based on fossil fuels and their byproducts to one that is knowledge- and service-based. Thus, students are likely to experience cognitive dissonance between resisting change, which would preserve the known benefits of the fossil fuel economy, and embracing change, which is associated with desirable but uncertain economic outcomes. The participants were a convenience sample of 390 undergraduate students of Saudi Arabian descent. During the post-pandemic period, students completed an online survey on their behaviors and attitudes toward a green economy. Students’ responses illustrated cognitive dissonance. Furthermore, favorable views of a green economy remained superficial. Most importantly, views (including attitudes and beliefs) were not good predictors of actions consistent with such views. Students’ contradictory answers stimulated faculty members in the College of Sciences and Human Studies to develop a plan to counteract cognitive dissonance and thus promote in students behaviors consistent with their overall favorable attitudes and beliefs toward a green economy.
Innovative Costing Methodology for Strategic Financial Planning and Resource Allocation: Navigating Budgetary Constraints to Drive Sustainable Growth and Business Leadership
Authors: Mittal Shobhit
Published: May 2024

This article presents a comprehensive examination of strategic financial planning and management within the dynamic and competitive business environment. It explores the critical importance of aligning financial resources with organizational goals and objectives to sustain growth and maintain a competitive advantage. Central to the discussion is the innovative methodology for overcoming budgetary constraints through strategic priority and alignment, emphasizing the need for a nuanced approach to investment that extends beyond traditional financial calculus. The article delves into the concept of the Fully Loaded Cost (FLC) of Full-Time Equivalents (FTEs), highlighting the significance of considering job family, business leadership, location, and grade level in calculating these costs. This detailed analysis provides organizations with the insights necessary for making informed decisions that optimize resource allocation and enhance the ability to navigate economic uncertainties with agility and foresight. Furthermore, the narrative underscores the importance of fostering a culture of innovation and adaptability, where strategic foresight becomes a key driver of success. It illustrates how the collaborative process of financial resource planning unites stakeholders to prioritize initiatives that promise the most favorable outcomes, thereby achieving strategic alignment and operational efficiency. Through a blend of strategic insight, original financial costing techniques, and case studies, this article offers a roadmap for business leaders to navigate the financial needs inherent in business leadership. It advocates for a strategic approach to financial planning that enables organizations to overcome budgetary constraints and positions them for long-term success and resilience in the face of competitive pressures and economic fluctuations. The article concludes by envisioning a future where financial strategy and organizational goals are in perfect harmony, driving innovation, growth, and competitive advantage in an ever-changing business environment.
Designing Learning Content and Experiences for Innovative Higher Education to Foster Soft Skills
Authors: Kim Eunyoung
Published: May 2024

To cope with upcoming challenges in education, almost all the higher educational institutes have reached a consensus on reforming their pedagogical methods to foster creativity and innovation for both learners and educators. In line with this, we need to raise fundamental questions about why we learn, how, and what to teach. This study proposes a procedural method for designing learning content for innovative education to foster soft skills in higher education. This study adopted an extensive systemic literature review to suggests a pedagogical approach to designing and co-designing the learning content and learning experience based on the learning objective level. This process consists of six steps: 1) extracting the topics to learn, 2) setting the objectives of learning, 3) designing the learning content and learning experience, 4) reflecting on the educational practices, 5) assessing the learning experiences, and 6) redesigning by co-creating. This research developed a blended learning course using an online learning platform to share the content as open resources. The results of this research, as a form of a course content, are implemented in a usual educational setting in a higher educational institute as a pilot study, and to be co-developed with appropriate learning content and pedagogical methods in further research for innovative education.
THE APPLICATION OF CERTAIN PENALTIES TO A PERSON SENTENCED TO IMPRISONMENT AS A WAY TO ENSURE THE SAFETY OF INSTITUTIONS OF THE PENAL ENFORCEMENT SYSTEM
Authors: Pronina Ol’ga
Published: May 2024

The author considers the procedure for applying a penalty in the form of a disciplinary fine to a convicted person. The purpose of the study is to identify the causes and conditions of law–abiding behavior of convicts in the context of the relationship of preventing violations of law and order in places of detention. Based on the analysis of the practical activities of correctional institutions, it is concluded that it is advisable to apply a disciplinary fine against convicts who are recognized as malicious violators of the established procedure for serving their sentences. In the conclusions, the author also formulates proposals for a potentially new educational approach to violators of the established procedure for serving sentences within the framework of current legislation by applying financial influence measures.
CORRELATION BETWEEN MELASMA AND QUALITY OF LIFE IN WOMEN IN SEBANI VILLAGE, TARIK DISTRICT, AND SIDOARJO DISTRICT
Authors:   Faculty of Medicine, Widya Mandala Catholic University Surabaya, Utomo Zelda Fidellia Natasha , Putri Maria Patricia Dian ,   Department of Skin and Venereal Diseases, Faculty of Medicine, Widya Mandala Surabaya Catholic University, Suwandito L ,   Faculty of Medicine, Widya Mandala Surabaya Catholic University
Published: May 2024

Background: Melasma has another name chloasma, derived from the Greek word "melas" which means black. Melasma is usually found on the cheeks, forehead, nose, chin, and the area above the lip. The majority of melasma will appear in women who have dark skin with certain histories such as pregnancy, never using sunscreen resulting in exposure to ultraviolet (UV) rays, use of hormonal contraception. Purpose: Knowing the relationship between melasma and the quality of life of mothers in Sebani Village, Tarik District, Sidoarjo Regency. Methods: The design of this research is analytic observational using cross sectional method. The number of samples in the study were 67 people. Data analysis used the t-test and Spearman's correlation. Result: The results of the study found that most of the respondents aged 46-50 were 43 people (64.2%). The average MASI of people exposed to the sun >6 hours, namely 27.41, was higher than people exposed to the sun <6 hours, namely 18.09. The average MASI of people who do not use sunscreen, which is 27.41, is higher than those who do not use sunscreen, which is 18.09. The average MASI for people who use birth control pills is 28.47, higher than people who don't use birth control pills, which is 25.02.. The relationship between melasma and quality of life was analyzed using the Spearman correlation test and found r = 0.823 and p = 0.000. Conclusion: There is a very strong relationship between melasma and quality of life
HASHIMOTO THYROIDITIS IN 7-YEAR-OLD CHILDREN: A CASE REPORT
Authors:   General Practitioner, Sunardi Wenny , Beyeng Rosalia Theodosia Dateng ,   Pediatrician, Lewoleba Regional Hospital, Siwi Putu Ianta Parama ,   Department of Paediatrics, Udayana University
Published: May 2024

Hashimoto thyroiditis (AIT) is a common cause of hypothyroidism that can occur in childhood and adolescence (ages six to sixteen years) and often occurs in women. AIT can be determined by increases in TSH with normal thyroid hormone serum levels. The diagnosis of AIT based on clinical symptoms of hypothyroid, biochemical results, and ultrasound images. Treatment is carried out by administering levothyroxine at an initial dose of 1 – 2 g/weight/day. This case report aims to show that AIT can show a wide range of symptoms and effects from the treatment that given to patient.
CORRELATION OF PHYSICAL FUNCTIONAL CAPACITY AND SLEEP QUALITY IN THE ELDERLY AT GOTONG ROYONG HOSPITAL
Authors:   Faculty of Medicine, Widya Mandala Catholic University Surabaya, Sugiyanto Calista Sekar Langit Acintya , Wijono Steven ,   Department of Tropical Medicine, Faculty of Medicine, Widya Mandala Surabaya Catholic University, Christy Ari ,   Department of Internal Medicine, Faculty of Medicine, Widya Mandala Surabaya Catholic University
Published: May 2024

Introduction: Old age is a period that indicates a process of physical, mental, and social deterioration over time. There are several things that concern health in old age, one of which is functional status which is a major health problem in the elderly. A person's ability to perform daily activities can be assessed by their functional capacity. Physical functional capacity can be measured using the six-minute walk test (6MWT). There have been many studies that discuss the 6MWT, but none have specifically looked for the relationship between physical functional capacity and sleep quality in the elderly. Purpose: This study was conducted with the aim of knowing the relationship between physical functional capacity and sleep quality in the elderly at Gotong Royong Hospital. Methods: This study used an analytic observational research design with a cross sectional approach. Data were collected from demographic questionnaires, Pittsburgh Sleep Quality Index (PSQI), and direct 6MWT measurements. Data analysis in this study used univariate and bivariate analysis. Results: In this study, the results obtained p = 0.000 (p < 0.05) indicate that there is a significant relationship between physical functional capacity and the quality of sleep of the elderly at Gotong Royong Hospital. Conclusion: There is a relationship between physical functional capacity and elderly sleep quality at Gotong Royong Surabaya Hospital.
PERSONAL HYGIENE AND THE INCIDENT OF SCABIES: COMPREHENSIVE CASE MANAGEMENT AT PHC SURABAYA HOSPITAL
Authors:   Faculty of Medicine, Widya Mandala Surabaya Catholic University, Harijati Erna , Julian Alvin ,   Department of Skin and Venereology, PHC Hospital Surabaya
Published: May 2024

Introduction: One of the risk factors for scabies is poor hygiene. Scabies is a skin condition caused by infestation and sensitization to the Sarcoptes scabiei var. hominis mite. While scabies can be treated, it is often diagnosed late, leading to delayed treatment and easy spread within groups. Objective: This paper aims to present a case of scabies in a patient who contracted the infection within the school environment, emphasizing the importance of hygiene and health awareness, particularly regarding skin health, to prevent disease transmission. Case Report: The patient presented to the Skin and Venereology Clinic at PHC Hospital with complaints of generalized itching persisting for 3 months, similar to symptoms experienced by classmates. The itching was accompanied by the presence of small ulcers. Treatment involved the application of Sulfur precipitatum Cream 10%, Krotamiton Cream 10%, and Permethrin Cream 5% once, to be left on for 8-10 hours (with a repeat application after 1 week), along with Cetirizine 10 mg. Conclusion: After weekly evaluations over 3 months, coupled with pharmacological therapy and adherence to hygiene practices, the patient returned symptom-free and without complications.
PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY IN SUBCLAVIAN VEIN STENOSIS CAUSED BY CENTRAL VENOUS CATHETERIZATION FOR HEMODIALYSIS ACCESS IN CHRONIC KIDNEY DISEASE PATIENTS
Authors:   Faculty of Medicine, Widya Mandala Surabaya Catholic University Indonesia, Laksono Gerardo , Motulo Yosis Y ,   Thoracic, Cardiac, and Vascular - Endovascular Surgery Department PHC Hospital Surabaya Indonesia, Tahalele Paul L ,   Surgery Department, Faculty of Medicine, Widya Mandala Surabaya Catholic University Indonesia
Published: May 2024

Introduction: The increased of central vein access for hemodialysis in chronic kidney disease patients has led to increase of side effect in clinically relevant stenosis of subclavian vein. One of therapeutic options to solve stenosis of subclavian vein is endovascular treatment Percutaneous Transluminal Angioplasty (PTA) . Objectives: To show our experience in treating subclavian vein stenosis using Endovacular treatment Percutaneous Transluminal Angioplasty (PTA). Materials and Methods: A retrospective study in 62 chronic kidney disease patients who undergo hemodyalisis with stenosis of subclavian vein treated with PTA in 3 hospitals in Surabaya from October 2017-October 2020 with range age 18-70 years was conducted . Results: We performed PTA for subclavian vein stenosis in 62 cases. Partial stenosis was found in 35 cases and total occlusion in 27 cases. For 27 total occlusion cases, 19 cases can still be opened, but 8 cases can’t be opened or recanalization and we drop out these patient. 54 cases (87%) were good and 8 cases (13%) can’t be open. The result of PTA in treating stenosis of subclavian vein was good. The result of reduced in arm swelling and using doppler USG follow up are 100%(54/54) after 1 month, 100%(54/54) after 3 months, 90.7% (49/54) after 6 months. Conclusion: Percutaneous Transluminal Angioplasty (PTA) is effective in treating subclavian vein stenosis reliefe its symptomps. The patency rate is 90.7% after 6 months post procedure of PTA.
Essays on Income Inequality
Authors:   , van Bezooijen Emiel Florentijn Sebastiaan
Published: May 2024

This dissertation consists of three empirical studies closely related to income inequality.

The first study focuses on the minimum wage — an important labor market institution to address income inequality at the lower end of the wage distribution. I study the effect of a 15-19% increase in the Dutch age-specific minimum wage applicable to workers aged 20-22 on the employment outcomes and earnings of those affected age groups. I use a difference-in-differences research design to trace the impact of the minimum wage increase throughout the age-specific wage distribution. I show that the increase in the age-specific minimum wage raised the wages of workers aged 20-22 in low-paid jobs, without adversely affecting the number of jobs held and total hours worked by those workers.

The second study focuses on firm wage-setting (i.e. monopsony) power, which allows firms to pay wages below the competitive market wage without losing a substantial share of their employees. This can have important consequences for income inequality if firms possess more wage-setting power over certain groups of workers or when certain groups of workers are disproportionately employed in industries or occupations characterized by a higher degree of firm wage-setting power. I quantify the degree of firm wage-setting power in the Dutch labor market by estimating labor supply elasticities to firms, using a matched event-study research design. In addition, I explore whether firm wage-setting power varies across industries and different groups of workers. I find that in the Dutch labor market as a whole, firms can potentially pay wages 12% below the competitive market wage. Moreover, I find that firms possess more wage-setting power over women compared to men, potentially contributing to the gender wage gap. Additionally, firms have relatively high wage-setting power over the lowest- and highest-paid workers.

The third study focuses on the relationship between the characteristics of the neighborhood in which children grow up and their educational achievement — a key determinant of future labor market prospects. I exploit a Dutch refugee dispersal policy to estimate the causal effect of the neighborhood share of individuals with a shared ethnic background as the child (i.e. co-ethnic concentration) on the education outcomes of refugee children. I show that the effect of co-ethnic concentration is moderated by the average earnings of individuals with shared ethnic background as the child in the neighborhood (i.e. co-ethnic earnings). Growing up in a neighborhood with a higher co-ethnic concentration increases the probability that refugee- children obtain an academic track diploma in secondary school or enroll in higher education when co-ethnic earnings are relatively high. The opposite effect is found when co-ethnic earnings are relatively low.
The Role of Plants in Contemporary Swedish and Norwegian Picturebooks
Authors: Reed Beatrice G.
Published: May 2024

The plant kingdom is vital to all other life on earth and is a fundamental part of children’s culture. Yet, we have little knowledge about how plants are currently represented in picturebooks aimed at children. In this article, I conduct a quantitative analysis of plant motifs in picturebooks published in Sweden and Norway in 2020. Inspired by concepts drawn from ecocritical children’s literature research and critical plant studies, the article investigates which plant species and types the books contain and how they are presented through text and pictures. Although the study finds that plants are prevalent motifs in contemporary Swedish and Norwegian picturebooks, it also shows that vegetal entities are often backgrounded and depicted as generic plant types.
Stigmatisation, Marginalisation, and Agency in Keluarga Cemara, an Indonesian Young Adult Series
Authors: Sachmadi Ida Farida , Priyatna Aquarini , Rahayu Lina Meilinawati
Published: May 2024

Keluarga Cemara [Cemara's family], a series by Arswendo Atmowiloto, displays how the wealthy characters stigmatise the characters living in poverty. The series centres on a petite-bourgeois family shifting from riches to rags, but it entails no downgrading shift from their class to the working class. The depiction of the family members and their interaction with other people shows that, despite the shift of economic capital, the family maintains their habitus as the petit bourgeoisie. The series presents a further problem in the way that this poverty-stricken family responds to the stigmatisation by accepting their dispossession of economic capital but objecting that of cultural capital, showing an exercise of agency in negotiating their position in the petit-bourgeois class. The wealthy disapprove of their cultural capital and marginalise them, revealing the desire of the wealthy to be distinct from them. We argue that in presenting the marginalisation practised by the wealthy and the agency by the low-wealth family, the series portrays the field of struggle where both try to maintain their position in social space. As such, the series clears an open textual space that allows the young adult readership to question the social structural imaginary that they inhabit.
Immunotherapeutic implications on targeting the cytokines produced in rhinovirus-induced immunoreactions
Authors: Sang Le , Gong Xia , Huang Yunlei , Zhang Linling , Sun Jian
Published: May 2024

Rhinovirus is a widespread virus associated with several respiratory diseases, especially asthma exacerbation. Currently, there are no accurate therapies for rhinovirus. Encouragingly, it is found that during rhinovirus-induced immunoreactions the levels of certain cytokines in patients' serum will alter. These cytokines may have pivotal pro-inflammatory or anti-inflammatory effects via their specific mechanisms. Thus far, studies have shown that inhibitions of cytokines such as IL-1, IL-4, IL-5, IL-6, IL-13, IL-18, IL-25, and IL-33 may attenuate rhinovirus-induced immunoreactions, thereby relieving rhinovirus infection. Furthermore, such therapeutics for rhinovirus infection can be applied to viruses of other species, with certain practicability.
Human cytokine and coronavirus nucleocapsid protein interactivity using large-scale virtual screens
Authors: Tomezsko Phillip J. , Ford Colby T. , Meyer Avery E. , Michaleas Adam M. , Jaimes Rafael
Published: May 2024

Understanding the interactions between SARS-CoV-2 and the human immune system is paramount to the characterization of novel variants as the virus co-evolves with the human host. In this study, we employed state-of-the-art molecular docking tools to conduct large-scale virtual screens, predicting the binding affinities between 64 human cytokines against 17 nucleocapsid proteins from six betacoronaviruses. Our comprehensivein silicoanalyses reveal specific changes in cytokine-nucleocapsid protein interactions, shedding light on potential modulators of the host immune response during infection. These findings offer valuable insights into the molecular mechanisms underlying viral pathogenesis and may guide the future development of targeted interventions. This manuscript serves as insight into the comparison of deep learning based AlphaFold2-Multimer and the semi-physicochemical based HADDOCK for protein-protein docking. We show the two methods are complementary in their predictive capabilities. We also introduce a novel algorithm for rapidly assessing the binding interface of protein-protein docks using graph edit distance: graph-based interface residue assessment function (GIRAF). The high-performance computational framework presented here will not only aid in accelerating the discovery of effective interventions against emerging viral threats, but extend to other applications of high throughput protein-protein screens.
Progress and application of lung-on-a-chip for lung cancer
Authors: Li Lantao , Bo Wentao , Wang Guangyan , Juan Xin , Xue Haiyi , Zhang Hongwei
Published: May 2024

Lung cancer is a malignant tumour with the highest incidence and mortality worldwide. Clinically effective therapy strategies are underutilized owing to the lack of efficient models for evaluating drug response. One of the main reasons for failure of anticancer drug therapy is development of drug resistance. Anticancer drugs face severe challenges such as poor biodistribution, restricted solubility, inadequate absorption, and drug accumulation. In recent years, “organ-on-a-chip” platforms, which can directly regulate the microenvironment of biomechanics, biochemistry and pathophysiology, have been developed rapidly and have shown great potential in clinical drug research. Lung-on-a-chip (LOC) is a new 3D model of bionic lungs with physiological functions created by micromachining technology on microfluidic chips. This approach may be able to partially replace animal and 2D cell culture models. To overcome drug resistance, LOC realizes personalized prediction of drug response by simulating the lung-related microenvironment in vitro, significantly enhancing therapeutic effectiveness, bioavailability, and pharmacokinetics while minimizing side effects. In this review, we present an overview of recent advances in the preparation of LOC and contrast it with earlier in vitro models. Finally, we describe recent advances in LOC. The combination of this technology with nanomedicine will provide an accurate and reliable treatment for preclinical evaluation.
Pioneering nanomedicine in orthopedic treatment care: a review of current research and practices
Authors: Liang Wenqing , Zhou Chao , Zhang Hongwei , Bai Juqin , Long Hengguo , Jiang Bo , Liu Lu , Xia Linying , Jiang Chanyi , Zhang Hengjian , Zhao Jiayi
Published: May 2024

A developing use of nanotechnology in medicine involves using nanoparticles to administer drugs, genes, biologicals, or other materials to targeted cell types, such as cancer cells. In healthcare, nanotechnology has brought about revolutionary changes in the treatment of various medical and surgical conditions, including in orthopedic. Its clinical applications in surgery range from developing surgical instruments and suture materials to enhancing imaging techniques, targeted drug delivery, visualization methods, and wound healing procedures. Notably, nanotechnology plays a significant role in preventing, diagnosing, and treating orthopedic disorders, which is crucial for patients’ functional rehabilitation. The integration of nanotechnology improves standards of patient care, fuels research endeavors, facilitates clinical trials, and eventually improves the patient’s quality of life. Looking ahead, nanotechnology holds promise for achieving sustained success in numerous surgical disciplines, including orthopedic surgery, in the years to come. This review aims to focus on the application of nanotechnology in orthopedic surgery, highlighting the recent development and future perspective to bridge the bridge for clinical translation.
Recent advances in earth-abundant transition metal-catalyzed dihydrosilylation of terminal alkynes
Authors: Lee Chanmi , Lee Dohun , Hong Sung You , Jung Byunghyuck , Seo Sangwon
Published: May 2024

Over the past few years, earth-abundant transition metal-catalyzed hydrosilylation has emerged as an ideal strategy for the synthesis of organosilanes. The success in this area of research has expanded to the advancements of alkyne dihydrosilylation reactions, offering broadened synthetic applications through the selective installation of two silyl groups. In particular, catalysts based on Fe, Co, and Ni have engendered enabling platforms for mild transformations with a range of distinct regioselectivity. This mini-review summarizes recent advances in this research field, highlighting the unique features of each system from both synthetic and mechanistic perspectives.
Enhancing STEAM education through augmented reality: the EduAR open platform experience
Authors: Velarde-Camaqui Davis , Celaya-Ramírez Rosario , Contreras-Fuentes Yéssica , Sanabria-Z Jorge
Published: May 2024

Quality education is pivotal for fostering innovation and development, with Augmented Reality (AR) offering transformative learning experiences. The absence of open-access platforms for AR resources hinders the democratization of educational technology. This study introduces EduAR, an open-access platform designed to provide validated AR resources for STEAM education, aiming to enhance learning processes and promote equitable access to quality education. Employing a mixed-methods approach, the platform’s usability was assessed using the System Usability Scale (SUS), where it achieved a high usability score, highlighting its user-friendliness and effectiveness. Additionally, qualitative feedback through focus groups provided insights into the platform’s impact on learning engagement and skill development. The study yielded the following findings: (a) Incorporating AR in STEAM disciplines through an open validated platform is an effective strategy for enriching learning and teaching processes; (b) The EduAR platform allows effective adoption due to its high usability and accessibility; (c) Design-Based Research is useful when looking to improve an AR educational platform; (d) EduAR is a valuable tool for providing equitable access to quality educational resources; and (e) EduAR promotes problem-solving and critical thinking among students. This comprehensive research underscores the potential of EduAR in enhancing educational outcomes, establishing a solid foundation for future advancements in educational technology and open educational resources (OER). Its benefit is foreseen for both teachers and researchers interested in the implementation of AR in courses within the framework of openness.
Investigating the nonlinear carbon reduction effect of AI: empirical insights from China’s provincial level
Authors: Xie Tongping , Wang Xuwei
Published: May 2024

In the context of rapid advancement in automation and increasing global warming, understanding the impact of artificial intelligence (AI) on carbon emissions (CES) is a cutting-edge research topic. However, there is limited focus in existing research on the nonlinear carbon reduction effect (CRE) of AI. This paper first theoretically elaborates the dual impact mechanisms of AI on CES and illuminates the nonlinear carbon reduction mechanisms of AI. Then, this study employs panel data encompassing 30 Chinese provinces between 1997 and 2019 to empirically test the net effect of AI on CES and the nonlinear carbon reduction effect of AI through econometric models. The results are as follows: first, although AI can both reduce and increase CES, AI primarily helps decrease CES. This conclusion holds true even after considering robustness, endogeneity, and spatial heterogeneity. Secondly, relative to the central and western regions, AI has significant achievement in reducing carbon intensity and per capita CES in the eastern region. However, there is still room for improvement in terms of reducing the total CES in the eastern region. Thirdly, improving the AI development level (AIDL) can magnify the marginal CRE of AI and lead to a nonlinear CRE of AI. Lastly, even if the AIDL remains constant, improving the level of marketization, human capital, digital infrastructure, economic development, openness, and government intervention can also amplify the marginal CRE of AI and lead to a nonlinear CRE of AI. To fully harness the potential of AI for green development, concerted efforts should be directed towards enhancing the innovation and application of AI technologies with carbon reduction potential.
Prediction model for transmission line icing based on data assimilation and model integration
Authors: Wang Guoyu , Shen Jie , Jin Minghong , Huang Shuai , Li Zhong , Guo Xinchun
Published: May 2024

With the increase of extreme weather events such as cold waves, power transmission line icing has become more and more severe, affecting the safe and stable operation of power systems. Thus, icing prediction has become crucial for power grids. In this study, we collect multi-source data including the historical observations of meteorological elements and transmission line icing in Sichuan during 2017–2019, and develop an artificial intelligence (artificial intelligence)-based integrated model to achieve icing thickness prediction according to meteorological elements. Using the Weather Research and Forecasting model and the three-dimensional variational data assimilation method, we analyze the weather conditions in Sichuan of China during the 2020 winter, and obtain the high-precision meteorological element fields that are related to icing prediction. The forecasted meteorological elements are then combined with the AI-based integrated model to predict icing conditions, assisting in the warning of transmission line icing. The results indicate that the AI-based integrated model displays superior performance on the accurate prediction of icing thickness in the test set, with only two samples having prediction errors of more than 3 mm. Data assimilation can effectively improve the forecast accuracy of meteorological elements near icing observation stations and thus enhance the accuracy of icing thickness prediction. In particular, icing thickness prediction is remarkably improved at Gaoqiao, Laolinkou and Erlangshan stations.