bluuebunny/crossref_metadata_2025 huggingface dataset:
Does it make sense to study heart rate variability in episodes of paroxysmal atrial fibrillation during the 24-hour electrocardiographic monitoring?
Authors: Arkhipov M. V. , Markov N. S. , Bozhko Ya. G. , Ushenin K. S. , Solovieva O. E.
Published: August 2022

Aim. To study the characteristics of heart rate variability (HRV) in episodes of paro xysmal atrial fibrillation (AF) and sinus rhythm (SR) during the 24-hour Holter electro cardiographic (ECG) monitoring and to assess the presence and nature of their relationships.

Material  and  methods. We analyzed 37 records of 24-hour Holter ECG monitoring obtained from patients with paroxysmal AF. For analysis, records were selected from the Long Term Atrial Fibrillation database (LTAFDB) (n=26), as well as from the long-term storage database “Myocard-holter” of the Sverdlovsk Regional Clinical Hospital № 1 (n=11). Each record contained at least 120 min of SR and at least 120 min of paroxysmal AF episodes. In addition, 48 HRV indices were calculated independently for SR and for AF episodes, after which the 96 HRV parameters obtained for each record were subjected to exploratory data analysis.

Results. Analysis of HRV in AF paroxysm showed a significant increase in the RMSSD, SD1, pNN50 indices, which confirmed the great importance of parasympathetic influence in the regulation of AF. Despite the fact that single HRV parameters in AF are not directly related to any single parameters in SR, we have shown that the AF is not completely chaotic and independent of the characteristics of baseline HR variability. We found that for some of the HRV indices determined during AF paroxysm (PAF_CVI, PAF_pNN20, PAF_pNN50, PAF_ApEn, PAF_SDNN, PAF_SD2), up to 74% of the variance of these indices can be explained using multivariate linear models, including 4 HRV indices for SR and taken as predictors. It was shown that among all the indices analyzed, only the PAF_HTI, calculated in paroxysmal AF, had a moderate negative correlation with the duration of AF episodes (r=0,60, p<0,01).

Conclusion. It is shown that the study of HRV indices on AF paroxysm has a wide clinical and electrophysiological potential. The paper proposes statistical models that demonstrate the relationship between HRV in SR and in the rhythm of AF episode. The PAF_HTI index, assessed on episodes of AF, showed a relationship with the duration of AF episodes, which suggests the expediency of using HRV characteristics on AF to assess the possibility of SR recovery.
Potential of combination therapy in patients with hypertension and dyslipidemia
Authors: Gorokhova T. V. , Perepech N. B.
Published: August 2022

This article provides an overview of data on the role of hypertension and dyslipidemia as the leading factors determining the clinical course of athero sclerotic diseases. The need for a multifactorial approach to the treatment of patients with multiple risk factors for the progression of such diseases is noted. The article describes the results of large-scale international studies confirming the clinical benefits of combined antihypertensive and lipid-lowering therapy. From the point of view of current clinical guidelines and the available evidence base, the potential for improving adherence to treatment using a combination of anti hypertensive and lipid-lowering drugs are presented. The article discusses the prospects for optimizing the therapy of comorbid patients using a triple fixed-dose combination, including amlodipine, atorvastatin and perindopril.
Apropriação e expropriação das terras indígenas na cidade de São Paulo
Authors: Oliveira Robson Silva , Zanetti Valéria Regina , Papali Maria Aparecida Chaves Ribeiro
Published: August 2022

Resumo São Paulo é o quarto município com maior presença dos povos indígenas no Brasil. Neste artigo relacionamos o processo de crescimento da cidade de São Paulo com a situação histórica dos povos indígenas dessa cidade. Temos como foco a incorporação dos indígenas no processo colonizador, a partir da expropriação de suas terras, para garantir a ocupação e o avanço da posse do território colonial. Por fim, analisamos o processo de periferização desses povos como sintoma histórico, que surge também com um instrumento da ação estatal para o desenvolvimento da cidade e de seus aparelhos urbanos. Esta análise é feita por meio de uma revisão bibliográfica de autores clássicos e contemporâneos e dos relatórios que abordam o tema.
Empirical and numerical study of the static lateral response of socketed pile in Dubai, UAE
Authors: Mughieda Omer , Alzo’ubi Abdel Kareem , Alzaylaie Marwan , Vandanapu Ramesh , Sharma Akash
Published: August 2022

In geotechnical engineering practice, it is often a challenging task to select a suitable method for the calculation of the lateral load capacity of piles. In Dubai, UAE piles are predominantly rock socketed with top layers commonly medium dense to dense sand or Dubai sedimentary rock contributing to bearing lateral loads. In the present study, the results of two lateral load field tests on piles were selected and used for evaluating various methods adopted by local geotechnical engineers for evaluating lateral load capacity. For the selected piles, the top layers of the ground lithology consist of medium dense to dense sand, which is critical in the evaluation of the lateral capacity of piles. Generally, either the Broms method or p–y non-linear analysis is adopted by local geoengineers for lateral load analysis of piles due to the simple input requirements and quick calculations. With advancement in computing capabilities, geotechnical engineers also adopt numerical analyses. As part of this study, various methods adopted were evaluated in terms of their advantages, limitations and accuracy in predicting the lateral load behaviour of piles. Commonly adopted methodologies such as the Broms method were found to have limitations that underestimate pile capacities, resulting in overdesign of pile sizes leading to higher costs, whereas, comparatively, numerical approaches predict more accurately the lateral load behaviour of piles.
Representaciones sociales de infancia y educación infantil: las voces de los adultos
Authors: Córdoba-Andrade Leonor , Robledo-Castro Carolina , Del Basto-Sabogal Liliana Margarita
Published: August 2022

Objetivo: Establecer cómo representan los conceptos de infancia y educación en la infancia los maestros de educación infantil y las familias. Método: Se llevó a cabo un estudio cualitativo-descriptivo, con la participación de 12 diadas familia-maestro; mediante la construcción de redes de asociaciones y entrevistas. Resultados: Los principales resultados muestran puntos de convergencia en cuanto a las representaciones sociales de familias y maestros. Los participantes representaron a la infancia como construcción social en función de la relación adulto-infante y la infancia como una etapa crucial en el desarrollo del ser humano y; a la educación infantil como sinónimo de amor y un derecho. Emergieron dos categorías bisagra entre infancia y educación en la infancia, el juego y la formación en valores. Discusión y Conclusiones: persiste la mirada del niño como un sujeto de cuidados y protección distanciándose de los avances teóricos y legales evidenciados en las últimas décadas. Con estos resultados se espera avanzar en la reflexión en torno a la relación existente entre las representaciones sociales de infancia y de educación en la infancia y la práctica pedagógica de los maestros, con miras a contribuir a una mejor calidad de la educación en este nivel, considerado fundamental en el desarrollo y formación del sujeto.
Morphological, physicochemical and health characterization of a selection of multipattern clones of soursop (Annona muricataL.)
Authors: Marmolejo G. Doris , Gamarra G. Delia P. , Paitan A. Elizabeth N. , Marmolejo G. Karina J.
Published: August 2022

The objective of this research work was to characterize and identify multipattern clonal grafts with morphological, physicochemical,and health characteristics to obtain good yields and fruit pulp quality in soursop populations. The descriptor list for soursop, recommended by CORPOICA, was used to characterize the fruit and pulp of the clonal plants. For the quantitative and qualitative morphological characterization of the fruit, the statistical software InfoStat was used, and to determine the most outstanding characteristics of the pulp, the software SPSS Ver. 24 was used. The chemical analysis of the pulp was done by means of the non-parametric techniques of Kruskal Wallis. In the qualitative characterization of the pulp, 43.1% showed white and snow-white color, 42.1% had an acid flavor, 57.9% had a medium texture and 44.7% had a medium aroma and 36.8% had a high aroma, 50% proved to be semi juicy. The pH found ranged between 4.70 and 2.92, with respect to the total soluble solids expressed in ºBrix, averaging 17.10. It is concluded that there is genetic variability in qualitative and quantitative characters of the fruit and pulp in grafted clones and differences were found in the chemical analysis of the pulp of clonal plants.
Jam based on “passion fruit” (Passiflora edulisSims) pulp and peel sweetened with stevia
Authors: Flores More Fiorella Stefany , Sosa León José Luis
Published: August 2022

Passiflora edulis Sims. It has great importance in the agroindustry through jam, it offers nutritional properties among the most outstanding vitamin C and fiber content. Currently the use of natural sweeteners (stevia) is an alternative in the agro-industrial sector. The objective was to take advantage of the passion fruit pulp and peel to make jam at different levels of pulp-peel ratio and sugar-stevia ratio, determining the level of sensory acceptance of the factors at the consumer level. In the experimental methodology, a DBCA with a 3x2 factorial arrangement with 6 treatments and three replications was considered. As a result of the physicochemical characterization of the raw material, it was in pulp the Brix degrees 14.62 °, pH 2.62, maturity index 4.59 and percentage of citric acidity 3.19 and in the peel (mesocarp) yellow color, pH 4.02, Brix degrees 3.16 and % acidity 0.33. The jam produced complies with the parameters required by NTP 203.047. 1991(2017); the T6 pulp-peel ratio (52-48) and sugar-stevia ratio (60-40), obtained greater organoleptic acceptance by the 40 consumers who evaluated the characteristics of color, flavor, smell, and texture on the 7-point hedonic scale.
Abundance and diversity of lepidoptera in San Benito, Cajamarca, Perú
Authors: Ramírez-Cruz Aureliano Florencio , Saldaña-Chafloque Charles Frank , Valderrama-Alfaro Shirley Madeleine
Published: August 2022

Determination of the abundance and diversity of Lepidoptera in the Andean Community of San Benito, Cajamarca, Peru. Several samplings were carried out, using the 500 linear m transect technique, with a monthly frequency throughout 2021, in the riparian areas and surrounding vegetation. The material was dissected and studied in the entomology laboratory of the National University of Trujillo. The analyzes of abundance and diversity of the Lepidoptera species were carried out. 206 individuals were registered, corresponding to 7 families, 9 subfamilies, 6 belonging tribes and 20 species. It is also reported that the families with the highest number of species are the Nymphalidae with 9 species and Pieridae with 5 species. it was determined that the Simpson index (0.94) represents a high diversity of species, the Shannon-Wiener index (2.81) represents a medium diversity of species and the Margalef index (5.06) represents a high diversity of lepidoptera species. The most abundant species are the representatives of the Nymphalidae family. The diversity indices represent a high, medium and high diversity of Lepidoptera species.
Physicochemical characterization, bioactive compounds and antioxidant capacity of the juice and flour of secondary cladodes of Opuntia ficus-indica
Authors: Cachay-Morante Jose , Chacpi-Vasquez Medalí , Castillo-Sebastian Gustavo , Huamani-Calle Diana
Published: August 2022

Prickly pears (Opuntia ficus-indica) are one of the most valued species due to their ability to develop on soils with low access to nutrients and water and great nutritional value in their fruits and leaves. However, the frequent pruning of "secondary cladodes" generates agroforestry residues thatdonothave a secondaryuse, hence the present study sought to characterize the nutritional and bioactive properties of the "secondary cladodes" from the district of Santiago de Tunato develop a baseline for its possible ulterioruse as raw material. For the assays, two types of samples were used: the juice and the flour of the cladode, in which a proximate analysis was conducted, and the concentration of polyphenols, Vitamin C, flavonoids, and antioxidant activity were determined. The juice presented a yield of 53% while the flour of 7.3%. Both the juice and the flour presented considerable amountsof polyphenols (105.1 mg GAE/100g -769 GAE/100g), vitamin C (56.2 mg AA mg/100g -114.6 mg AA mg/100g) and antioxidant capacity (1247.94 μmol Trolox/g -2585 μmol Trolox/g). Therefore, the results indicated that cladodes can be used to develop products with exciting potentialin the food industry.
Organic liquid amendments in the reduction of cadmium in soil, leaves and cocoa beans
Authors: Zavala-Solorzano José Wilfredo , Repoma-Rodriguez Daniela Nicole , Lao-Olivares Ceila Paquita , Aguilar-Guizado Jhon Kenet
Published: August 2022

The objective of the study was to evaluate the effect of the application of two organic amendments (biol and liquid carbon) on the cadmium of the soil, leaves and almonds of the cocoa crop, plantation CCN-51 (Theobroma cacaoL.), five years of production, in the province of Huamalíes, Huánuco region, Peru. The research used a completely randomized block design (RCDB) with a factorial arrangement of 3 x 3 + 1 additional control. Total cadmium in the soil, leavesand cocoa beans was evaluated. The lowest content of total cadmium in the soil was determined when applying 50 L/ha of biol (0.13 ppm of cadmium) and when applying 4 L/ha of liquid carbon (0.12 ppm of cadmium); while, without the application of organic liquid amendments, the average value was 0.36 ppm of cadmium. Likewise, T5 (80 L/ha of biol + 4L/ha of liquid carbon) reduces the available cadmium content of the soil by 73.58%; while T4 decreases the cadmium content in leaves and almonds by 43.83% and 62.96%, respectively.
The morphological faces of Barra da Tijuca in Rio de Janeiro (Brazil)
Authors: Pasquotto Geise Brizotti
Published: August 2022

The urban revolution of Barra da Tijuca-RJ was characterized by a late growth, due to its location, to be an immense sand and concentration of great extensions of land in the hands of a few. This finding reflects subsequent actions in the region, where the real state growth process and road connections were the focus of urban actions. Lucio Costa's pilot plan, with modernist characteristics, arises from the need to anticipate the uncontrolled and inevitable ocupation process of the area. The plan aimed to prevent the reprodution of what had happened with other neighborhoods on the Rio de Janeiro coast, which were experiencing intense densification.

After 50 years, several changes were made to update the plan to the present, to remedy some points in which the plan did not have enough detail and many that succumbed to real estate pressures.

In this way, this article aims to analyze the transformations that took place in Barra da Tijuca, from the implementation of the plan to the current urban fabric, and verify the urban design performance and real estate pressure as modelers of the neighborhood.
Stem and Leaf Anatomical Studies of Selected Species of Barlerieae and Ruellieae (Acanthaceae) from Yemen
Authors: Al-Hakimi Anisa S. , Abdul Razak Sarah , Omar N. , Saeed Abdulwahab A. , Khamis Shamsul , A. Latiff A. Latiff
Published: August 2022

The anatomy of stems and leaves of selected species of tribes Barlerieae and Ruellieae (Acanthaceae) was studied to assess the taxonomic significance of anatomical characteristics in the two tribes. The anatomical characters such as the outline of stems, midribs, petioles, margins, shape of epidermal cells, vascular bundles, stomata, anticlinal cells, cystoliths, aerenchyma cells, layer of wax, layer of hypodermis were observed and analysed. Type of trichomes observed on the leaf surface using Scanning Electron Microscopy and light microscope provides information of taxonomic significance to both tribes and the taxa within them. The trichomes vary from non-glandular (unicellular, bicellular, multicellular, and multiradiate) to capitate glandular. Abundance of long-stalked trichomes was recorded only in Neuracanthus aculeatus. Cystoliths of different size and position are present in epidermis, parenchyma and collenchyma in addition to oil cells in some genera. The placement of Neuracanthus among the recognized tribes of Acanthaceae is assessed using anatomical characters.
(+)-Neocadambine A and (-)-nauclederine Isolated from the Bark of Neolamarckia cadamba (Rubiaceae) as Natural Advanced Glycation End Products (AGEs) Inhibitors
Authors: Othman Noor Aimi , Liew Sook Yee , Blanchard Patricia , Derbré Séverine , Chong Soon-Lim , Ali Abdul Manaf , Awang Khalijah
Published: August 2022

The phytochemical study on the dichloromethane extract of Neolamarckia cadamba (Roxb.) Bosser has afforded two indole alkaloids, (+)-neocadambine A (1) and (-)-nauclederine (2). Their structures were confirmed by extensive spectroscopic analysis and by comparing with the reported data. (+)-Neocadambine A (1) and (-)-nauclederine (2) exhibited potent inhibition activity of advanced glycation end products (AGEs) with IC50 values of 1.2 and 0.95 mM, respectively, while the latter was almost two times more potent than the standard, aminoguanidine (1.8 mM). This is the first report on the compounds isolated from this plant with AGEs inhibition activity. In addition, (-)-nauclederine (2) was isolated for the first time in the genus of Neolamarckia. Complete 1H-NMR and 13C-NMR of compound 2 were also reported.
Kehadiran Interaksi Supramolekul dalam SebatianPolimer Koordinatan Baharu Terbitan Ligan N,N’-2,6-bis(3-piridilmetil)piridina Dikarboksiamida
Authors: Mansor Nafisah , Haris Nur Shuhaila Haryani , Abdul Kadir Maisara
Published: August 2022

Kehadiran beberapa interaksi supramolekul seperti ikatan hidrogen dan susunan pi-pi adalah penting bukan sahaja untuk menstabilkan struktur molekul tetapi juga memainkan peranan sebagai molekul perumah. Oleh itu, dalam kajian ini, ligan berasaskan amida yang mempunyai bentuk U iaitu N,N’-2,6-bis(3-piridilmetil)piridina dikarboksiamida (L1) telah digunakan sebagai ligan yang berupaya membentuk ikatan hidrogen dengan anion, dan kajian ini berfokus kepada peranannya dalam keadaan polimer koordinatan. Sebagai permulaan, L1 ditindakbalas dengan beberapa logam peralihan melalui kaedah penyejatan perlahan untuk menghasilkan tiga polimer koordinatan yang baharu. Polimer koordinatan ini mempunyai formula molekul, {[Cd(L1)2(H2O)2](NO3)2.H2O}n (1), {[Cd(L1)2(H2O)2](ClO4)2}n (2) dan {[Co(L1)2(H2O)2](NO3)2}n (3) yang dicirikan melalui analisis unsur, FTIR spektroskopi dan kristalografi sinar-X. Polimer koordinatan 1, 2 and 3 menghablur dalam sistem triklinik dan kumpulan ruang P-1. Konformasi sebatian ini digambarkan sebagai logam-makrosiklik dinuklear yang tersusun seperti rantai leher. L1 didapati bersambung melalui logampusat daripada atom nitrogen, secara berulang-ulang untuk membentuk jaringan satu dimensi. Struktur molekul sebatian baharu ini distabilkan oleh kehadiran ikatan hidrogen intermolekul dan intramolekul, yang terjadi di kawasan NH amida, serta susunan pi-pi di antara gelang aromatik piridina. Dalam struktur hablur ini juga, jaringan metilina membentuk ikatan hidrogen dengan kaunter anion pada moieti2,6-piridina dikarboksamida, menunjukkan potensi sebagai sebatian penerima anion. Kajian DFT telah dijalankan untuk mengenal pasti tenaga interaksi kompleks.
Comparison of Non-Alcoholic Fatty Liver Disease (NAFLD) Model using Diet-Induced Nafld Mice with Genetically Modified Mice
Authors: Mohd Efendy Goon Mohd Danial , Ab Rahim Sharaniza , Abd Latip Normala , Abdul Aziz Mardiana , Mohd Noor Norizal , Lew Sook Weih , Mazlan Musalmah , Sheikh Abdul Kadir Siti Hamimah
Published: August 2022

Prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing steadily every year affecting all population both Western and Asian countries. The current treatments available for NAFLD are non-conclusive warranting newer effective pharmacological agents. Newly formulated agents require prior testing using animal models. However, in developing countries, these models are often costly. The possibility of using more affordable animal model in local settings should be investigated. In this study, ten Institute of Cancer Research (ICR) and seven B6.Cg-LepOb/J leptin-knockout (JAX) male mice were recruited. Five ICR and all JAX mice were subjected to high-fat diet (60% kcal fat) and remaining ICR mice were given standard diet (SD) for six weeks. Body weight and food intake were measured weekly while abdominal circumference, random blood glucose and liver span were measured at the end of the HFD study. Livers collected were subjected to histology assessment. Compared to ICR group, JAX group presented with significantly higher body weight (58 ± 0.72, p<0.05), larger body weight changes (16.57 ± 0.81, p<0.05), more HFD intake (197.14 ± 0.812, p<0.05) and larger abdominal circumference (11.79 ± 0.34: p<0.05). Liver from JAX group appeared with general steatosis and presentation of high-grade panacinar steatosis, low number of lobular inflammations and minimal fibrosis. Liver of ICR mice showed Zone 3 steatosis with high number of lobular inflammations without fibrosis. The NAFLD characteristics presented in JAX group suggested that B6.Cg-LepOb/J mice developed characteristics of NAFLD resembling human while ICR is suitable NAFLD model resembling human population resilient towards NAFLD.
Fusidic Acid/Tea-Tree Oil Nanoemulsions: A Potentially Safe and Effective Anti MRSA/MSSA Topical Agent for Chronic Wound Healing
Authors: Yaseen Ahmed , Mohammed Ghareeb Mowafaq , Alsaffar Dania F. , Parumasivam Thaigarajan , Toh Seok-Ming , Mohd Gazzali Amirah
Published: August 2022

Fusidic acid (FA) is clinically used as an antibacterial agent for the treatment of Gram-positive bacterial infections. It interferes with bacterial protein synthesis, specifically by preventing the translocation of the elongation factor G on the ribosome. In the present work, oil-in-water nanoemulsion (NE) was developed as a carrier for the transdermal delivery of FA. Different oils, surfactants and co-surfactants were screened. The solubility of FA, the emulsifying capacity of the surfactants and phase diagrams for each oil and surfactant mix were constructed. From the analysis, eight stable NE formulations were chosen, and their physicochemical properties were further evaluated. The antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) were also evaluated, and cytotoxicity was conducted on HS-27 cell line to determine the safety of the formula. It was found that the NE produced from tea tree oil has the most optimal stability with promising antibacterial activity against MRSA as compared to a commercially available product. The safety profile of the NE was also comparable to the commercial product; thus, the formulated FA-NE is promising for clinical use.
Approximate-Analytic Solution of Hyperchaotic Finance System by Multistage Approach
Authors: Rangkuti Y.M. , Alomari A.K. , Anakira N.R. , Jameel A.F.
Published: August 2022

This paper devotes to constructing an approximate analytic solution for the hyperchaotic finance model. The model describes the time variation of the interest rate, the investment demand, the price exponent, and the average profit margin. The multistage homotopy analysis method (MHAM) and multistage variational iteration method (MVIM) are utilized to generate the analytical solutions. The solutions are presented in terms of continuous piecewise functions without interpolation. These procedures prove their applicability for this kind of model due to rapidly convergent series solutions with easily computable terms, iterates, and efficiently obtained by applying it over multiple time intervals. We also provide the convergences theorem of the MHAM. Numerical comparisons are displayed with the results obtained by MHAM, MVIM, and the fourth-order Runge-Kutta method to demonstrate the validity and effectivity of this procedure.
Determinants of COVID-19 Prevention Equipment Readiness in Families during Pandemic in Indonesia
Authors: Aditya Sukma Pawitra Aditya Sukma Pawitra , Khuliyah Candraning Diyanah Khuliyah Candraning Diyanah , Latif Mohd. Talib , Zakaria Zainul Amiruddin , Al Firdausi Salsabila
Published: August 2022

Indonesia was the country with the second-highest case of COVID-19 in the South East Asia Region (SEAR) of the World Health Organization (WHO) data until August 1, 2021. As an infectious disease, the high level of COVID-19 rate transmission requires everyone always to prepare a prevention tools kit to minimize the risk of coronavirus exposure. This study aimed to analyze the determinant factors of readiness of the COVID-19 prevention tools kit. This study used a cross-sectional design with a mix-method technique because data collection and analysis combine quantitative and qualitative approaches in several phases of the research process. Data collected from 18 representative provinces in Indonesia with a total of respondents involved were 2,196 people. The Binary Logistic Regression tests were used to analyze the variable correlation. The multivariable analytic showed that the determinant factors with a significant correlation which affected the readiness of COVID-19 prevention tools kit in each family during pandemic in Indonesia were age 37-46 years old (p=0.000; odds ratio=8.039), female gender (p=0.000; odds ratio=8.653), self-employed jobs (p=0.028; odds ratio=2.239), income > 5 million per month (p=0.000; odds ratio=7.267), good knowledge (p=0.000; odds ratio=3.311), and good perception (p=0.001; odds ratio=2.015). The supply of tools and medicines to prevent COVID-19 is indispensable during the pandemic to protect against COVID-19 infection. Masks and hand sanitizers become the main kits most individuals have, especially when doing outside home activities. At the same time, the oximeter becomes the least kit in the family. This preparation also teaches citizens to practice a healthy lifestyle. Cross-sector coordination is needed to improve public awareness of COVID-19 prevention equipment.
PRECIPITATION REGIME PROJECTIONS FOR THE TERRITORY OF UKRAINE IN THE NEXT THIRTY YEARS
Authors:   Odessa State Environmental University, Khokhlov V.M. , Zamfirova M.S. ,   Odessa State Environmental University
Published: August 2022

This study presents possible changes in the number of days per year with precipitation ≥ 1 mm for the territory of Ukraine in relation to the period 1961-1990, based on data from an ensemble of CORDEX models created to study the global climate based on an assessment of climate trends at the regional level. In the article, calculations were performed using one of the four possible scenarios for emissions and concentrations of greenhouse gases, which serve as the basis for modern scientific research on future climate projections, namely RCP4.5. This trajectory predicts a steady increase in radioactive forcing compared to the pre-industrial era and a peak in greenhouse gas emissions in 2030-50. For the calculation, the indicators of 177 meteorological stations of our country and 16 simulations of the above project were used. To assess climate change, climate indicators are usually used, such as average annual, seasonal and monthly average values of climatic elements (air temperature, wind direction and speed, precipitation, etc.). However, at the beginning of this century, in order to supplement traditional climatic indicators, scientists developed a system of quantitative indicators for monitoring, analyzing and evaluating changes in extreme climatic indicators, based on daily averages of meteorological observations, called “extremity indices”. The study is based on the calculation of one of the above-mentioned indices, namely the climate index RR1 – the number of “wet days”, that is, the number of days with a daily precipitation of more than 1 mm. The article analyzes the typical precipitation regime for Ukraine and its predicted changes, taking into account regional characteristics. The study revealed a tendency to increase the number of wet days per year from 10 cases in the south-west of the country to 50 on the slopes of the Ukrainian Carpathians and a change in the localization of the driest region from Kherson to Odessa region. There is also an increase in the minimum and maximum values of the number of days with precipitation (by 14 and 8 cases, respectively). From the foregoing, we can assume a change in the nature of moisture supply in the next thirty years for the whole of Ukraine. An increase in the number of days with precipitation is expected throughout the study area, especially in the north and west, and a change in the location of the most arid regions.
Clinical and functional features of chronic bronchitis in agricultural workers
Authors: Syurin S. A. , Temirbulatov Kh. A. , Savchenko V. M.
Published: August 2022

We examined 337 patients with chronic bronchitis - agricultural workers, of which 203 were exposed to adverse occupational factors. In patients of the main group, more pronounced manifestations of bronchial obstruction, violations of the relationship between the most important indicators of the immune status, disorders of erythropoiesis and lipid metabolism were revealed. When carrying out therapeutic measures, active restoration of bronchial patency, the use of influences aimed at correcting the immune status, the processes of erythropoiesis and lipid metabolism are necessary.
Changes in the exocrine function of the pancreas under various therapeutic effects
Authors: Pevchikh V. V. , Trusov V. V.
Published: August 2022

The external secretory function of the pancreas changes under the influence of various therapeutic effects. Using the methodological experience of M. M. Gubergritsa, A. Ya. Gubergritsa, N. K. Shlygin, K. M. Prostyakova, etc., we studied the effect of cholinolytic (hexonium, gangleron, dicoline) and hormonal (ACTH, prednisolone, methylandrostenediol) drugs on the exocrine function of the pancreas, as well as radioactive iodine (in the treatment of patients with diffuse toxic struma). Studies using the complex methodology were conducted in clinical conditions in 357 patients.
Serum proteins in patients after card and gastrectomy
Authors: Ryabov B. D.
Published: August 2022

In the long term, after cardectomies and especially gastrectomies, patients experience a number of complications associated with loss of functions of the entire stomach or its upper part. One of them is weight loss, leading some patients to severe exhaustion.
H. A. Zondag. Determination and diagnostic significance of lactate dehydrogenase isoenzymes. 118 p., 24 fig. Assen, 1968
Authors: Kureeva N. S. , Sviridov N. K.
Published: August 2022

This book is the first successful attempt to summarize the literature data and the author's own research on the definition and diagnostic evaluation of lactate dehydrogenase isoenzymes. The monograph is written on the basis of the analysis of 4000 studies and accounting of the work of exclusively foreign laboratories and clinics. Among the 290 cited works in the bibliography there is no reference to any work of Soviet scientists. Meanwhile, in our country, the biochemical determination of lactate dehydrogenase isoenzymes is successfully used, especially in the pathology of the cardiovascular system.
About the causes of hypogalactia in women
Authors: Kulakova G. A. , Shoshina N. K. , Ziatdinov I. G. , Agafonova E. V.
Published: August 2022

Natural feeding in the first year of life is of great importance for the normal physical development of the child, the correct formation of his psycho-emotional sphere. At present, despite the success in studying various nutritional formulas for artificial feeding, all domestic and foreign pediatricians recognize the benefits of breastfeeding and are its ardent supporters. However, the number of children who receive early supplementary feeding and are transferred to artificial feeding is still high. The main reason for the transfer of infants to artificial feeding is hypogalactia - reduced secretory ability of the mammary glands. It is important to study the causes of hypogalactia, the development of effective methods for its prevention and treatment.
Single point anesthesia for nasal septum surgery
Authors: Bobrov V. M.
Published: August 2022

The technique of conducting anesthesia is described and its anatomical rationale is given from one point during a septum operation performed for a hematoma of the nasal septum. This anesthesia is performed taking into account the anatomical features of the structure, blood supply, innervation of the nasal septum, and therefore it allows submucosal resection of the nasal septum painlessly, economically in time, by introducing an anesthetic subperchondrium.
Postoperative complications in transosseous compression-distraction osteosynthesis
Authors: Khabibyanov R. Ya. , Kazantsev F. F. , Evseev E. M.
Published: August 2022

Treatment of injuries and diseases of the musculoskeletal system with external fixation methods has been practiced for a long time and is deservedly considered one of the most effective in the arsenal of orthopedic traumatologists. For the first time, transosseous osteosynthesis with the simplest apparatus was used in 1629 by Fabricius Hildanus. A qualitatively new stage in the development of transosseous osteosynthesis is observed at the beginning of this century. Since the 1950s, the method of extrafocal compression-distraction osteosynthesis has been widely used in world practice and is constantly being improved.
The value of ultrasound in the diagnosis of abdominal pregnancy
Authors: Bakhtiyarov I. A. , Maltsev L. I.
Published: August 2022

In some cases, it is very difficult to establish abdominal pregnancy according to a clinical examination. Ultrasound echography may play a leading role in the diagnosis of this pathology.We present our observation confirming the value of ultrasound in the diagnosis of full-term abdominal pregnancy.
Clinical course of viral hepatitis B in a patient with post-abortion endometritis complicated by staphylococcal sepsis
Authors: Shigapova G. M.
Published: August 2022

In the literature, there are few data on purulent-septic manifestations in viral hepatitis. A number of authors point to the prognostic value of bacteremia in liver cirrhosis. It is known that as liver failure increases, prerequisites for bacterial-viral reinfection appear.
Toxoplasma infection rate of fur farm workers
Authors: Sergeeva N. A.
Published: August 2022

400 workers of the fur farm and 246 people of the control group were examined. The level of infection with toxoplasma in Tatarstan in the general population is 22%, and in the risk group it is almost 2 times higher - 42.7%.
To the casuistry of the external section of the esophagus with foreign bodies
Authors: Kharitonov I. F.
Published: August 2022

There cannot be two opinions on the issue of methods of removing foreign bodies from the esophagus at present. The best way is extraction by means of an esophagoscope. But at the same time, there are cases when even in the hands of experienced specialists, the esophagoscope does not justify the hopes placed on it. So, in the Gakker clinic, in 10% of all cases of extraction of foreign bodies from the esophagus, they were forced to resort to bloody intervention, in the clinic of Prof. Warriors in 23%, according to the statistics of Shem Meg at 508 sl. extraction of foreign bodies in 16 cases (3.2%) required surgical removal, according to Saxen, in 61 cases 3 times (5%). The reason for refusing to use the esophagoscope is the neglect of the case when the edematous, swollen mucous membrane of the esophagus, limiting the field of view of the esophagoscope, is fraught with the danger of rupture. With periesophageal phlegmon, abscess, the external section of the esophagus pursues not only the purpose of extracting a foreign body, but is also a therapeutic intervention, giving a wide flow of pus from the mediastinal space. In the conditions of our reality (the absence of esophagoscopes, specialists), the external section of the esophagus is often the only reliable and safe way to extract foreign bodies from the esophagus and subject to early surgery.
A case of hypospadias in a newborn
Authors: Vadovsky V.
Published: August 2022

On 20/XI 29, a child was born in the Kandarat hospital, whose sex was difficult to determine.
Case of atresia in the cervical canal post conception
Authors: Kaminsky B. M.
Published: August 2022

Cervical canal atresia is not uncommon. By their origin, they are congenital, extremely rare, and acquiredmore frequent. The reasons for the latter are very diverse. Acquired cervical canal atresia can develop after operations, such as: after plastic surgery on the cervix (Emmet, discisio colli, amputatio colli, etc.), after vaginal Caesarean section, after removal of cervical polyps, after severe labor with forceps, after abrasio uteri, accompanied by deep scraping of the mucosa in the orific area. int. and cervical canal; after vaporization of the uterus (atmocausis); after cauterization of erosions and endocervicitis with strong cauterizing substances and Paqu1in, as well as after prolonged abandonment of tampons in the uterus, causing the formation of bedsore ulcers in the cervical canal (Tsomakion); after curitherapy; as a consequence of tuberculous ulcers (Ludwig, Kraemer, Schiffmann), etc. My case of atresia is as follows.
Prof. Ya. S. Arkavin and Dr. S. Ya. Shaferstein. Prevention and therapy of childhood diseases. Published. "Scientific Thought". Kharkiv. page 335.
Authors: Breitman M. Ya.
Published: August 2022

Many of those graduating from medical school have to start their work on the periphery away from large medical centers, where they are deprived of the opportunity to use the advice of their older, more experienced comrades.
F. Dumаrеst et R. Brette. La pratique du pneumothorax thérapeu tique et de la collapsothérapie chirurgicale. Page 409, Figure 54, Table 30. Paris Masson et Cie. C. fr.-50
Authors: Breitman M. Ya.
Published: August 2022

Within a short time, the book went through 3 editions.
Sanitary provision of the population of the Republic of Tatarstan for the 43rd anniversary of October
Authors: Mukhutdinov I. Z.
Published: August 2022

The Soviet people, like all progressive humanity, are celebrating the significant date the 43rd anniversary of the Great October Socialist Revolution with new outstanding achievements.
The condition of the teeth and oral cavity in diseases of the digestive organs
Authors: Weiss S. I. , Anisimova T. I.
Published: August 2022

The facts testifying to the connection of dental and gastrointestinal diseases are not new (S. E. Gelman, Ya-S. Pekker, B. A. Torchinsky and T. I. Matveeva). However, since due attention is not paid to this connection in practical work, we have set ourselves the task of finding out which of the oral diseases are most frequent and significant on the basis of a thorough examination of the oral cavity of those suffering from gastrointestinal diseases.
About the essence of endarteriosis and the principles of its treatment
Authors: Zaitsev G. P.
Published: August 2022

During 1938-1959, 1,862 patients with diseases of the arteries of the lower extremities were treated in the clinic we managed. The largest number of them relates to endarteriosis and atherosclerosis. These two diseases of the arterial system have a lot in common according to a number of clinical signs and the course of the process. However, these are different diseases, primarily by etiology. There are many differences in their clinical and pathomorphological manifestations.
Experience of emergency surgical care for acute processes in the abdominal cavity in a district hospital
Authors: Miftakhov N. A.
Published: August 2022

The organization of emergency surgical care in the surgical departments of district hospitals in rural areas has its own characteristics.
Features of the diphtheria clinic in children fully vaccinated with diphtheria toxoid
Authors: Lavrovа К. V.
Published: August 2022

Although the lighter course of diphtheria in vaccinated patients, compared with unvaccinated ones, is generally recognized, however, there are two opinions regarding the comparative characteristics of the acute period of diphtheria in those vaccinated with diphtheria toxoid and unvaccinated ones. Some believe that active immunization does not have any effect on the duration of the first (acute) period and, consequently, the cleansing of the pharynx from raids, the improvement of the general condition occurs in the same time as in unvaccinated (E. M. Borok, N. A. Nikitina, N. I. Nisevich). Others note that in the actively immunized, the acute period proceeds more favorably: the raids go down faster, the general condition improves earlier than in the unvaccinated, and the one-sidedness of the tonsils is more often observed in the picture of the throat (A.D. Levasheva, V. N. Azbelev, N. P. Kudryavtseva, N. K. Belaya, V. L. Olshevskaya, E. M. Dmitrieva-Ravikovich, S. N. Rozanov). At the same time, in a larger number of cases, there is a discrepancy between the severity of the general condition and the amount of plaque (with severe intoxication, the raids are limited, localized).
Bicillin-1 in the treatment of pneumonia
Authors: Movchan L. A. , Spasskaya L. A.
Published: August 2022

In 1951, Elies, Price and Mirion reported on a new durant drug of penicillin called "bicillin" and "benzetacil".
A case of multiple xanthomatosis
Authors: Saburova V. A.
Published: August 2022

Reticulo-xanthomatosis, or Christian-Schueller's disease, which is rare, is characterized by spleno-hepatomegaly, diabetes insipidus, bug-eyed, destruction of flat bones. It occurs more often in children of 4-5 years of age, less often in adults. The symptoms of the disease are directly related to xanthomatous infiltration of the skull bones, mainly the eye socket and the Turkish saddle. The lesion of the skull is a classic sign and is designated by Schueller as a landkart-shaped skull.
Perforation of the uterus with infringement of the ileum loop in it during abortion
Authors: Dobrinsky Ya. A.
Published: August 2022

In the gynecological department 26/III-57, she was taken from a rural hospital, accompanied by a doctor, b-naya K -, 30 years old, with complaints of severe pain throughout the abdomen, repeated vomiting and spotting. On the day of admission, during the abortion, during a pregnancy of 10 weeks, I suddenly felt a severe abdominal pain, after which I vomited.
On the epidemiological characteristics of dysentery in the Bavli district of the TASSR
Authors: Nabiyev E. G.
Published: August 2022

To study the main patterns of the epidemic process of dysentery, we processed 2533 maps of the epidemiological examination of acute dysentery foci and 636 case histories from the district hospital for 1950-58.
About the article by Professor I V. I. Katerov| and P. X. Burnasheva "Pathogenetic therapy and prevention of hypertension in a new light" in the "Kazan Medical Journal"
(No. 6, 1959)
Authors: Googlin E. R.
Published: August 2022

The article on hypertension begins with the indication that " significant success in the fight against this common disease is not yet noticeable." Further, the authors emphasize that in the whole problem of hypertension, "the most significant and remarkable clinical fact is the undoubted connection of changes in chloride metabolism with the height of blood pressure: achloride and subchloride diets lead to a decrease in blood pressure, the addition of table salt to food, on the contrary, increases it."
Laparoscopic cholecystectomy experience in the Republic of Tatarstan
Authors: Chugunov A. N. , Voitsekhovich V. N. , Shakirov M. D. , Rechkovsky L. R. , Uсolov Y. A.
Published: August 2022

Cholelithiasis (GI) is one of the most common diseases. Despite the widespread promotion of such alternative methods of treatment as extracorporeal lithotripsy, dissolution of stones with pharmacopreparations, endoscopic and percutaneous extraction of concretions, most gastroenterologists prefer radical removal of the gallbladder as a source of cholelithiasis and subsequent complications [1, 2, 3].
Diagnosis of bronchial asthma in sensitization to yeast-like fungus candida albicans
Authors: Burnasheva R. K. , Gumerova A. M. , Glushko N. I. , Rakhmatullina N. M.
Published: August 2022

The peculiarities of bronchial asthma caused by hypersensitivity to antigens Candida albicans are studied.
Clinicomyographic characteristic of the pathology of neurotrophic regulation of skeletal muscles
Authors: Bogdanov E. I.
Published: August 2022

The clinical, electromyographic and mechanomyographic examinations of patients with diseases of central and peripheric nervous systems and the experimental myographic and morphohistochemical investigations of various models of impulsive and unimpulsive neurotrophic effect disorders on mice muscles arc performed. Based on the clinicoexperimen- tal comparisons the conclusions are drawn regarding the importance of mechanomyography in the diagnosis of neuromuscular system state, in the development of estimation methods of the course and efficacy of therapeutic and rehabilitation measures in neurogenetic lesions of muscles.
Fibronectin, hemostasis and phagocytosis
Authors: Litvinov R. I.
Published: August 2022

On the basis of experimental and literature data a hypothesis is proposed that plasma fibronectin serves as a mediator between hemostasis and RES. Fibronectin is thought to be an opsonic factor in the elimination of throm- bogenic particles from blood flow. As an example of thrombogenic particles soluble fibrin precursors covalently bound to plasma fibronectin are examined. Interrelated chages of plasma fibronectin level, DIC signes, and alterations of the Kupffer cells morphologic- and-functional state are in favor of the hypothesis. The idea is also proved by the presence of specific protein receptors for fibronectin on the surface of mononuclear phagocytes and neutrophils. It is suggested that plasma fibronectin and phagocytes represent a united antithrombotic mechanism which prevents excessive intravascular activation of hemostatic system in pathology.
Clinical prospects of the study of phagocytosis
Authors: Pikusa O. I. , Mayansky A. N.
Published: August 2022

The possibilities of the use of phagocyte dependent reactions in general clinical diegno- sis in the determination of m.edical tactics and control of health reserves are analyzed. The methods of functional estimate of phagocytosis which may be used for practical tasks are recommended. The prospects for the study of phogocytic mechanisms in the development of immunodeficient, allergic states, chronic inflammatory diseases are shown.
The main directions of scientific research of the Department of Occupational Hygiene and Occupational Pathology
Authors: Amirov N. X. , Sitdikova I. D.
Published: August 2022

The relevance of studying the problems of occupational health and occupational diseases is determined by the development of scientific and technological progress and an increase in labor productivity associated with the widespread spread of computer technologies.