bluuebunny/crossref_metadata_2025 huggingface dataset:
The SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia
Authors: Huang Jing , Tian Rui , Yang Yongqiang , Jiang Rong , Dai Jie , Tang Li , Zhang Li
Published: September 2017

It is generally regarded that Sirtuin 1 (SIRT1), a longevity factor in mammals, acts as a negative regulator of inflammation. However, recent studies also found that SIRT1 might be a detrimental factor under certain inflammatory circumstance. In this study, the potential pathophysiological roles and the underlying mechanisms of SIRT1 in a mouse model with endotoxemia-associated acute lung injury were investigated. The results indicated that treatment with the selective SIRT1 inhibitor EX-527 suppressed LPS-induced elevation of TNF-α and IL-6 in plasma. Treatment with EX-527 attenuated LPS-induced histological abnormalities in lung tissue, which was accompanied with decreased myeloperoxidase level and suppressed induction of tissue factor and plasminogen activator inhibitor-1. Treatment with EX-527 also suppressed LPS-induced phosphorylation of eukaryotic translation initiation factor-binding protein 1 (4E-BP1). Co-administration of a mammalian target of rapamycin (mTOR) activator 3-benzyl-5-[(2-nitrophenoxy) methyl]-dihydrofuran-2 (3H)-one (3BDO) abolished the inhibitory effects of EX-527 on 4E-BP1 phosphorylation. Meanwhile, the inhibitory effects of EX-527 on IL-6 induction and the beneficial effects of EX-527 on lung injury were partially reversed by 3BDO. This study suggests that selective inhibition of SIRT1 by EX-527 might alleviate endotoxemia-associated acute lung injury partially via suppression of mTOR, which implies that SIRT1 selective inhibitors might have potential value for the pharmacological intervention of inflammatory lung injury.
Setting the Stage: A Comparative Analysis of an Onstage/Offstage and a Linear Clinic Modules
Authors: Freihoefer Kara , Kaiser Len , Vonasek Dennis , Bayramzadeh Sara
Published: September 2017

Objective:

The purpose of this study was to understand how two different ambulatory design modules—traditional and onstage/offstage—impact operational efficiency, patient throughput, staff collaboration, and patient privacy.

Background:

Delivery of healthcare is greatly shifting to ambulatory settings because of rapid advancement of medicine and technology, resulting in more day procedures and follow-up care occurring outside of hospitals. It is anticipated that outpatient services will grow roughly 15–23% within the next 10 years (Sg2, 2014). Nonetheless, there is limited research that evaluates how the built environment impacts care delivery and patient outcomes.

Method:

This is a cross-sectional, comparative study consisted of a mixed-method approach that included shadowing clinic staff and observing and surveying patients. The linear module had shared corridors and publicly exposed workstations, whereas the onstage/offstage module separates patient/visitors from staff with dedicated patient corridors leading to exam rooms (onstage) and enclosed staff work cores (offstage). Roughly 35 hr of clinic staff shadowing and 55 hr of patient observations occurred. A total of 269 questionnaires were completed by patients/visitors.

Results:

The results demonstrate that the onstage/offstage module significantly improved staff workflow, reduced travel distances, increased communication in private areas, and significantly reduced patient throughput and wait times. However, patients’ perception of privacy did not change among the two modules.

Conclusion:

Compared to the linear module, this study provides evidence that the onstage/offstage module could have helped to optimize operational efficiencies, staff workflow, and patient throughput.
The Rome IV versus Rome III criteria for heartburn diagnosis: A comparative study
Authors: Zhang Mengyu , Chen Minhu , Peng Sui , Xiao Yinglian
Published: September 2017

Background

The phenotypes of heartburn patients are heterogeneous.

Objective

The objective of this study was to investigate the proportion of heartburn phenotypes in a Chinese population and to compare the Rome IV and III criteria for heartburn diagnosis.

Methods

A retrospective study was performed among heartburn patients referred for upper endoscopy and esophageal function tests in a tertiary hospital. Their symptoms fulfilled Rome IV and III criteria.

Results

A total of 233 patients were included. Fifty-nine patients (25%) were diagnosed with esophagitis, 96 (41%) with non-erosive reflux disease (NERD) and 78 (34%) with functional heartburn (FH) based on Rome III criteria. Approximately 70% of the Rome III NERD patients were changed based on Rome IV criteria, with 36 patients (15%) diagnosed with reflux hypersensitivity (RH) and 32 patients (14%) who didn’t fulfill the criteria considered unclassified. The FH and RH patients showed higher esophagogastric junction-contractile integral (EGJ-CI) and less hiatal hernia than did Rome IV NERD patients. The unclassified had more hiatal hernias than the FH and RH ( p < 0.05). The EGJ-CI was similar between Rome III NERD and FH cases.

Conclusion

The Rome IV criteria were stricter for heartburn diagnosis and superior in distinguishing NERD from functional disorders on motility patterns than Rome III.
Shock charity campaigns: Building our understanding on their effectiveness: Comments on “Emotions and Prosocial Behaviors: A Study of the Effectiveness of Shocking Charity Campaigns” by Jeanne Albouy
Authors: Dahl Darren W.
Published: September 2017

The recent article entitled “Emotions and Prosocial Behaviors: A Study of the Effectiveness of Shocking Charity Campaigns” authored by Jeanne Albouy published in Recherche et Applications en Marketing provides important evidence on the effectiveness of shocking advertisements in the context of charity appeals. Specifically, this research highlights how the negative emotions and empathy that are produced by shock campaigns lead to positive attitudes toward the ad, the cause, and the intentions to help the charity. This work is important because it helps to resolve a conflict in the literature – namely, divergent findings that have shown both positive and negative outcomes for ads in charity campaigns that are emotional and raw in nature. Furthermore, like any good research, this work also seeds new opportunities for future investigation into the role of shock advertising in the context of charity communication campaigns. This commentary will look to highlight where additional research opportunities exist. Specifically, the discussion will center on three directions of potential interest: (1) a broader investigation into the notion of shock advertising in the context of charity campaigns, (2) understanding potential differences in how an audience is exposed to shock advertising and the implications therein, and (3) contemplating other outcome measures that could provide meaningful insight into how shock advertising has an impact in the marketplace.
Homozygous Familial Hypercholesterolemia: Anesthetic Challenges and Review of Literature
Authors: Ladha Suruchi , Makhija Neeti , Kiran Usha , Aarav Sudheer K
Published: September 2017

Homozygous familial hypercholesterolemia (HoFH; Fredrickson IIa) is a rare autosomal dominant hereditary disease associated with increased low-density lipoprotein cholesterol. We hereby report anesthetic challenges in a rare case of HoFH having severe progressive aortic stenosis, mitral regurgitation, diffuse aortic and carotid vessel involvement, and severe left ventricular dysfunction. The patient underwent a Konno aortoventriculoplasty with mechanical prosthesis along with mitral valve repair.
Facilitating Chinese EFL Learners’ Critical Thinking Skills: The Contributions of Teaching Strategies
Authors: Wang Sheng , Seepho Sirinthorn
Published: September 2017

Many teaching strategies have been used to promote the development of critical thinking skills, among which the most frequently used are group discussion, concept mapping, and analytical questioning. The study aims to explore learners’ voice and learning experience in the pedagogical contributions of these strategies to the development of critical thinking skills in Chinese EFL (English as a Foreign Language) learners. One full university class was chosen as the sample in the instruction of critical thinking skills and to take part in a learner voice survey, among which 15 participants were chosen by purposeful sampling for semistructured interviews. The instruction of critical thinking was embedded in an English reading class by using the three teaching strategies, during which four interviews were conducted for each critical thinking skill. After the instruction of critical thinking skills was completed, all participants were surveyed with the learner voice questionnaire. The results show that participants thought the three teaching strategies could improve critical thinking skills. Each teaching strategy made unique and specific contributions to the development of critical thinking skills. These findings have pedagogical implications for using these teaching strategies in the instruction of critical thinking skills in Chinese EFL learners.
An Analysis of the Judicial Rulings for Transition Services Under the IDEA
Authors: Zirkel Perry A.
Published: September 2017

Starting with a constructive critique of legal articles in special education journals concerning transition services under the Individuals With Disabilities Education Act (IDEA), this article presents an empirical analysis of relevant judicial rulings for the period 1990–2016 that shows a prevailing prodistrict approach that is not otherwise evident in the prior articles. The findings include an increased frequency of these judicial rulings generally in accord with the trajectory of special education litigation and, more significantly, an approximate 3:1 district–parent ratio in the outcomes of these rulings that, with up-and-down variation, prevails for the entire period. The conclusion is that the time is ripe for an elevated substantive standard for law-based articles in special education journals as well as a continued, but differentiated, rigorous normative standard for transition services.
Recovery of Shoulder Rotational Muscle Strength After Arthroscopic Bankart Repair
Authors: Amako Masatoshi , Arino Hiroshi , Tsuda Yoshifumi , Tsuchihara Toyokazu , Nemoto Koichi
Published: September 2017

Background:

Shoulder rotational muscles act as dynamic stabilizers of the glenohumeral joint, and the recovery of muscle strength plays an important role in stabilizing the joint during postoperative rehabilitation. However, temporal changes in muscle strength after arthroscopic Bankart repair have not been clarified.

Purpose:

To better understand the temporal recovery of shoulder rotational muscle strength after arthroscopic Bankart repair.

Study Design:

Case series; Level of evidence, 4.

Methods:

Isokinetic concentric shoulder rotational muscle strength was evaluated in 50 patients who were diagnosed with recurrent dislocations of the glenohumeral joint and treated with arthroscopic Bankart repair.

Results:

The mean peak torque/weight and total work were reduced significantly at 1.5 months after surgery ( P < .0001) and returned to preoperative levels by 6 months for external rotation and 4.5 months for internal rotation. The contralateral peak torque ratios reached preoperative levels by 6 months after surgery. The ipsilateral peak torque ratios were reduced between 1.5 and 3 months after surgery and returned to preoperative levels at 6 months for external rotation and 4.5 months for internal rotation.

Conclusion:

Isokinetic shoulder rotational muscle strength after arthroscopic Bankart repair recovered to preoperative levels by 6 months for external rotation and 4.5 months for internal rotation.
Trends and patterns in sustainability-related media coverage: A classification of issue-level attention
Authors: Barkemeyer Ralf , Givry Philippe , Figge Frank
Published: September 2017

Sustainability has moved from fringe topic to headline news and key policy discourse in its own right. Yet, the sustainability discourse remains fragmented, with a diverse set of challenges receiving vastly different levels of attention. Nevertheless, the vast majority of previous studies have focused on media attention to climate change, whereas other sustainability challenges have received much less attention in the academic literature. In this paper, we explore trends and patterns in media coverage across a set of ten sustainability challenges. In particular, we are interested in the extent to which the recent trends and patterns in coverage that have been well-documented for climate change are reflected by other sustainability challenges. We utilise a sample of 23 broadsheet newspapers from five different countries (Australia, Canada, Germany, UK, US), covering a 17-year period from 2000 to 2016. Using the agenda-setting literature as a starting-point for our enquiry, we then turn to the toolset provided by financial econometrics to develop a basic typology of media attention focusing on the two dimensions information/noise and seasonality/non-seasonality. We find that media coverage on climate change, poverty and HIV/AIDS can mainly be characterized as information, whereas the remaining seven issues included in our study appear noise-driven. Seasonal patterns in coverage appear most pronounced for socioeconomic issues. Media attention to biodiversity and cleaner technologies has been crowded in by increased coverage on climate change. At the same time, we find clear divergences from overall trends and patterns at the level of different countries and individual newspapers.
Assessment of model validation outcomes of a new recursive spatial equilibrium model for the Greater Beijing
Authors: Wan Li , Jin Ying
Published: September 2017

Robust calibration and validation of applied urban models are prerequisites for their successful, policy-cogent use. This is particularly important today when expert assessment is questioned and closely scrutinized. This paper proposes a new model calibration-validation strategy based on a spatial equilibrium model that incorporates multiple time horizons, such that the predictive capabilities of the model can be empirically tested. The model is implemented for the Greater Beijing city region and the model validation strategy is demonstrated over the Census years 2000 to 2010. Through forward/backward forecasting, the model validation helps to verify the stability of the model parameters as well as the predictive capabilities of the recursive equilibrium framework. The proposed modelling strategy sets a new standard for verifying and validating recursive equilibrium models. We also consider the wider implications of the approach.
Non-destructive, high-content analysis of wheat grain traits using X-ray micro computed tomography
Authors: Hughes Aoife , Askew Karen , Scotson Callum P. , Williams Kevin , Sauze Colin , Corke Fiona , Doonan John H. , Nibau Candida
Published: September 2017

Background

Wheat is one of the most widely grown crop in temperate climates for food and animal feed. In order to meet the demands of the predicted population increase in an ever-changing climate, wheat production needs to dramatically increase. Spike and grain traits are critical determinants of final yield and grain uniformity a commercially desired trait, but their analysis is laborious and often requires destructive harvest. One of the current challenges is to develop an accurate, non-destructive method for spike and grain trait analysis capable of handling large populations.

Results

In this study we describe the development of a robust method for the accurate extraction and measurement of spike and grain morphometric parameters from images acquired by X-ray micro-computed tomography (μCT). The image analysis pipeline developed automatically identifies plant material of interest in μCT images, performs image analysis, and extracts morphometric data. As a proof of principle, this integrated methodology was used to analyse the spikes from a population of wheat plants subjected to high temperatures under two different water regimes. Temperature has a negative effect on spike height and grain number with the middle of the spike being the most affected region. The data also confirmed that increased grain volume was correlated with the decrease in grain number under mild stress.

Conclusions

Being able to quickly measure plant phenotypes in a non-destructive manner is crucial to advance our understanding of gene function and the effects of the environment. We report on the development of an image analysis pipeline capable of accurately and reliably extracting spike and grain traits from crops without the loss of positional information. This methodology was applied to the analysis of wheat spikes can be readily applied to other economically important crop species.
Myd88 is required for disease development in a primary Sjögren's syndrome mouse model
Authors: Kiripolsky Jeremy , McCabe Liam G , Gaile Daniel P , Kramer Jill M
Published: September 2017

Sjögren's syndrome (SS) is an autoimmune disease that often results in diminished exocrine gland function. SS patients also experience systemic disease manifestations, including hypergammaglobulinemia and pulmonary and renal pathoses. MyD88 is a ubiquitously expressed adaptor molecule used by all immune cells that is required for IL-1 receptor (IL-1R), IL-18R, and most TLR signaling. The precise role of MyD88 in SS has not been evaluated, although this adaptor is critical for development of lupus, a related autoimmune disease. This study tested the hypothesis that Myd88-mediated signaling is required for local and systemic SS manifestations. To this end, we generated NOD.B10Sn-H2b/J (NOD.B10) mice that are deficient in Myd88 (NOD.B10Myd88−/−). We found that NOD.B10 animals that lack Myd88 show reduced exocrine and extraglandular inflammation. Moreover, these animals are protected from loss of salivary flow. Splenocytes from NOD.B10Myd88−/− mice did not up-regulate activation markers or secrete IL-6 in response to a Myd88-dependent agonist, although BCR signaling remained intact. Finally, IgM, IgG, and anti-nuclear autoantibodies were reduced in NOD.B10Myd88−/− mice compared with the parental strain. These data demonstrate that Myd88 is a crucial mediator of local and systemic SS disease manifestations.
Characterization of buried cables and pipes using electromagnetic induction loop-loop frequency-domain devices
Authors: Thiesson Julien , Tabbagh Alain , Dabas Michel , Chevalier Antoine
Published: September 2017

The detection and characterization of buried cables and metal pipes has become a key component of field surveys carried out prior to excavation work on construction sites. The very high conductivity and magnetic permeability contrast between any buried cables/pipes compared with the soil makes electromagnetic induction (EMI) instruments very useful for their detection. We have developed a seminumerical method that can be used to model the responses of this type of target. A straight horizontal conductor is equivalent to a series of magnetic dipoles, the magnitude of which can be determined in the spectral domain and then converted back into the spatial domain through the use of an inverse fast Fourier transform. Simulations and case studies allow to establish rules of thumb for the estimation of (1) the nature of the metal: the in-phase response of magnetic cables is of the opposite sign from the conducting ones, (2) the sensitivity to the target characteristic: the influence of the cable/pipe diameter is greater than that of the metal properties, and (3) the depth of the cables. The simulations also underline the role of the coil configuration: Vertical coplanar and perpendicular responses allow a more precise location of the cable/pipe, whereas the horizontal coplanar response is less dependent on the orientation. As ground truth, a known electric cable buried at a depth of 0.5 and 0.002 m in diameter is determined at 0.56 m. The first field test is related to the detection of a buried military cable from World War I, between 2.5 and 3 m below the original ground level. The second field test is related to the detection of a water pipe 0.35 m deep. The modeling technique can be applied to all EMI prospecting methods, and thus it opens the way to the correction of the disturbances generated by cables and pipes.
Long-Term Use of Long-Acting Insulin Analogs and Breast Cancer Incidence in Women With Type 2 Diabetes
Authors: Wu Jennifer W. , Azoulay Laurent , Majdan Agnieszka , Boivin Jean-François , Pollak Michael , Suissa Samy
Published: September 2017

Purpose

The association between long-acting insulin analogs and increased breast cancer risk is uncertain, particularly with the short follow-up in previous studies. We assessed this risk long term in women with type 2 diabetes.

Methods

A population-based cohort of women 40 years or older, all of whom were treated with long-acting (glargine, detemir) or neutral protamine Hagedorn (NPH) insulin between 2002 and 2012, was formed using the United Kingdom’s Clinical Practice Research Datalink. Women were followed until February 2015 or breast cancer diagnosis. Cox proportional hazards models were used to estimate adjusted hazard ratios (HRs) and 95% CIs of incident breast cancer, comparing long-acting insulin analogs with NPH overall, as well as by duration and cumulative dose.

Results

The cohort included 22,395 women who received insulin treatment, with 321 incident breast cancer events occurring during up to 12 years of follow-up (incidence rate 3.3 per 1,000 person-years). Compared with NPH insulin, insulin glargine was associated with an increased risk of breast cancer (HR, 1.44; 95% CI, 1.11 to 1.85), mainly increasing 5 years after glargine initiation (HR, 2.23; 95% CI, 1.32 to 3.77) and after > 30 prescriptions (HR, 2.29; 95% CI, 1.26 to 4.16). The risk was particularly elevated among prior insulin users (HR, 1.53; 95% CI, 1.10 to 2.12) but not for new users, which included fewer patients and for which one cannot rule out an HR of 1.81. The risk associated with insulin detemir was not significantly elevated (HR, 1.17; 95% CI, 0.77 to 1.77).

Conclusion

Long-term use of insulin glargine is associated with an increased risk of breast cancer in women with type 2 diabetes. The risk associated with insulin detemir remains uncertain because there are fewer users of this insulin.
Untitled Land, Occupational Choice, and Agricultural Productivity
Authors: Chen Chaoran
Published: September 2017

The prevalence of untitled land in poor countries helps explain the international agricultural productivity differences. Since untitled land cannot be traded across farmers, it creates land misallocation and distorts individuals' occupational choice between farming and working outside agriculture. I build a two-sector general equilibrium model to quantify the impact of untitled land. I find that economies with higher percentages of untitled land would have lower agricultural productivity; land titling can increase agricultural productivity by up to 82.5 percent. About 42 percent of this gain is due to eliminating land misallocation, and the remaining is due to eliminating distortions in individuals' occupational choice. (JEL J24, J43, O13, P14, Q12, Q15, Q24)
Demand for Value Added and Value-Added Exchange Rates
Authors: Bems Rudolfs , Johnson Robert C.
Published: September 2017

We examine how cross-border input linkages shape the response of demand for value added to international relative price changes. We define a novel value-added real effective exchange rate (REER), which aggregates bilateral value-added price changes. Spillovers via input linkages lower the sensitivity of the value-added REER to price changes by supply chain partners because they counterbalance demand-side expenditure switching. Input linkages also raise the price elasticity of demand relative to the conventional REER framework, making demand more sensitive to REER changes. Using global input-output data, we demonstrate that these conceptual insights are quantitatively important in a case study of European competitiveness. (JEL E31, F23, F31, L14)
Recent advances in the understanding and management of Klebsiella pneumoniae
Authors: Calfee David P.
Published: September 2017

Klebsiella pneumoniae, a gram-negative bacillus of the Enterobacteriaceae family, is a component of the normal human microbiota and a common cause of community- and healthcare-associated infections. The increasing prevalence of antimicrobial resistance among K. pneumoniae isolates, particularly among those causing healthcare-associated infections, is an important public health concern. Infections caused by these multidrug-resistant organisms, for which safe and effective antimicrobial therapy options are extremely limited, are associated with poor outcomes for patients. The optimal approach to the treatment of infections caused by these multidrug-resistant strains remains undefined, and treatment decisions for an individual patient should be based on a number of organism- (for example, minimum inhibitory concentration) and patient-specific (for example, site of infection) factors. The emergence of pandrug-resistant strains of K. pneumoniae highlights the critical need for consistent implementation of effective strategies for prevention of transmission and infection and for the development of new antimicrobials with activity against these emerging pathogens.
Sample Preparation and Nucleic Acid-based Technologies for the Detection of Foodborne Pathogens
Authors: Lim Min-Cheol , Kim Young-Rok
Published: September 2017

There have been great efforts to develop a rapid and sensitive detection method to monitor the presence of pathogenic bacteria in food. While a number of methods have been reported for bacterial detection with a detection limit to a single digit, most of them are suitable only for the bacteria in pure culture or buffered solution. On the other hand, foods are composed of highly complicated matrices containing carbohydrate, fat, protein, fibers, and many other components whose composition varies from one food to the other. Furthermore, many components in food interfere with the downstream detection process, which significantly affect the sensitivity and selectivity of the detection. Therefore, isolating and concentrating the target pathogenic bacteria from food matrices are of importance to enhance the detection power of the system. The present review provides an introduction to the representative sample preparation strategies to isolate target pathogenic bacteria from food sample. We further describe the nucleic acidbased detection methods, such as PCR, real-time PCR, NASBA, RCA, LCR, and LAMP. Nucleic acid-based methods are by far the most sensitive and effective for the detection of a low number of target pathogens whose performance is greatly improved by combining with the sample preparation methods.
Extraction of Starch from Domestic Potato Sludge by Food-Grade Hemicellulase and its Physicochemical Properties
Authors: Choi Jung-Min , Park Cheon-Seok , Baik Moo-Yeol , Kim Hyun-Seok , Seo Dong-Ho
Published: September 2017

The objective of this study was to increase the efficiency of starch extraction from potato sludge by different concentration of food-grade hemicellulase. The potato sludge, which is a by-product of potato processing industry, was treated with food-grade hemicellulase. Starch extraction efficiency displayed no significant difference in hemicellulase concentration. The purities of potato starch increased from 83.40 to 95.91, 97.44, 95.58, and 97.79%, with treated 0.5, 0.75, 1.0, and 1.5% hemicellulase, respectively. The physicochemical properties of the starches, such as granule structure, particle size, pasting, and thermal transition, were not affected by the concentration of hemicellulase. These results indicate that food-grade hemicellulase treatment is an efficient method for starch extraction from potato sludge.
Effect of Medicinal Plant Extracts on the Ethanol-Metabolizing Enzyme Activities
Authors: Do Jaeho , Gwak Jungwon , Lee Sunjeong , Rho Jung Jin , Lee Kwangseung , Kim Dong Chung
Published: September 2017

This study was conducted to certify the effect of aqueous extracts from fifty medicinal plants on the activities of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in vitro. Each aqueous extract was prepared by combining one-part medicinal plants with twenty-parts distilled water at 80°C for 8 h. Among the fifty medicinal plants, Allium sativum L. and Cinnamomum cassia Presl were regarded as an effective anti-hangover substance. Allium sativum L. extract increased ALDH activity more than 2 times compared with ADH activity, enhancing the acetaldehyde degradation. Cinnamomum cassia Presl extract dramatically inhibited ADH activity compared with ALDH activity, thus potently decreasing the acetaldehyde formation. ADH and ALDH activities were proportionally inhibited according to the increased concentration of Cinnamomum cassia Presl extract. The aqueous extract of Cinnamomum cassia Presl at a concentration of 45.33 μg/mL inhibited ADH activity by 52.8% and ALDH activity by 11.0%.
‘She’s too big I hope for me to compass’: Fat suits, costuming and the construction of femininity in contemporary stagings of Shakespeare’s Comedy of Errors
Authors: Reimers Sara
Published: September 2017

The fat suit exists in a liminal space in theatre semiotics. On the one hand, it is an item of costume that influences how the body is read in performance, while on the other, it is an extension of the actor’s body, altering the way in which costume on that body reads. In a performance
context in which thin is the standard beauty ideal, the fat suit is a contentious item: a politically charged decision that is bound up with contemporary constructions of gender, beauty and desire. This article will explore the ways in which costuming, and particularly the fat suit, has been
used to depict the grotesque corporeality of the character of Luce in Shakespeare’s The Comedy of Errors. Exploring the performative quality of fat, it will demonstrate how fat is used as a signifying shorthand for all that is undesirable and grotesque about the character.
Book Reviews
Authors: Lennox Patricia , Taylor Madeline
Published: September 2017

Designers’ Shakespeare, John Russell Brown and Stephen Di Benedetto (2016)

New York and Oxon: Routledge, 200 pp.,

ISBN: 9780415618007, h/bk, £95, p/bk, £32.99

The Art and Practice of Costume Design, Melissa L. Merz (ed.) (2017)

New York and
London: Routledge, 310 pp.,

ISBN: 9781138828414, p/bk
‘Bound Coolies’ and Other Indentured Workers in the Caribbean: Implications for debates about human trafficking and modern slavery
Authors: Kempadoo Kamala
Published: September 2017

Under systems of indenture in the Caribbean, Europeans such as Irish, Scots and Portuguese, as well as Asians, primarily Indians, Chinese and Indonesians, were recruited, often under false pretences, and transported to the ‘New World’, where they were bound to an employer and the plantation in a state of ‘interlocking incarceration’. Indentureship not only preceded, co-existed with, and survived slavery in the Caribbean, but was distinct in law and in practice from slavery. This article argues that the conditions of Caribbean indenture can be seen to be much more analogous to those represented in contemporary discussions about human trafficking and ‘modern slavery’ than those of slavery. Caribbean histories of indenture, it is proposed, can provide more appropriate conceptual tools for thinking about unfree labour today—whether state or privately sponsored—than the concept of slavery, given the parallels between this past migrant labour system in the Caribbean and those we witness and identify today as ‘modern slavery’ or human trafficking. This article thus urges a move away from the conflation of slavery and human trafficking with all forced, bonded and migrant labour, as is commonly the case, and for greater attention for historical evidence.
Historicising ‘Irregular’ Migration from Senegal to Europe
Authors: Maher Stephanie
Published: September 2017

Contemporary discourses on migration from West Africa to Europe tend to frame migrants as victims of syndicated trafficking cartels that truck in human desperation. As part of this narrative, migrants are increasingly portrayed as ‘modern-day slaves’ in need of humanitarian protection. In both media and policy circles, African migrants are commonly referred to as desperate travellers who fall prey to exploitative ‘slave traders’ on their clandestine journeys to Europe. And yet, such framings do not adequately account for the ways in which migration from West Africa to Europe has a long and profound history, and thus does not sufficiently correspond to histories of enslavement. Nor do such framings appreciate how contemporary movements within and outside West Africa are informed by interrelated political genealogies that tie Europe to Africa in mutually dialectic ways. Focusing on the case of Senegal, this article aims to disrupt the ‘migrant as slave’ narrative by looking back at the histories of regional and international mobility that continue to shape population movements out of Senegal today.
Contra les lectures obligatòries: assaboreix-les!
Authors: Marqués Ferrer Cristina
Published: September 2017

El 90% de les programacions didàctiques dels departaments de llengües dels centres de Secundària i Batxillerat a Espanya estableixen la lectura obligatòria en l’avaluació de la matèria. Llegir esdevé condició sine qua non per a obtindre’n l’aprovat; en més del 70% dels casos, el mecanisme d’avaluació és el «control de lectura» i l’estudiant, senzillament, ha de fer veure que ha llegit l’obra prescrita. Contra l’obligatorietat, proposem l’experimentació lectora. És a dir, apostem per una lectura significativa, una lectura viscuda i participada; una lectura que permeta obrir les portes del coneixement i que descorde el plaer del descobriment. Amb aquesta perspectiva, l’experiència que proposem passa per viure la lectura, fer-la nostra, experimentar-la i, fins i tot, projectar les intel·ligències múltiples des del llibre mateix.
La competencia lecto-literaria para el desarrollo del pensamiento crítico. Estética y ética en la literatura infantil y juvenil
Authors: Terol Bertomeu Sara
Published: September 2017

La literatura i l’educació literària, a través de la formació de la competència lectoliterària, ofereixen al docent la possibilitat de fer despertar un pensament crític entre l’alumnat, de manera que s’eduquen com a lectors literaris i ciutadans en aquesta societat. La literatura fa possible un diàleg intel·lectual i afectiu entre persones diferents, raó per la qual el lector adquirirà experiències vitals i no només coneixements culturals i habilitats en l’apreciació lingüística literària.
La planificació i la realització d’una ruta poètica com a proposta de millora de l’educació literària i com a eina d’integració en l’entorn
Authors: Gregori Parra Àngels
Published: September 2017

Arran de l’observació de l’escassa presència del gènere poètic a l’aula, aquesta investigació analitza els avantatges de treballar el poema en el procés d’ensenyament-aprenentatge a partir de la realització d’una ruta literària, ja que pot esdevenir una forma suggeridora d’apropar el gènere a l’alumnat i aconseguir-ne bons resultats. Aquest article forma part del projecte I+D de la Conselleria d’Educació, Investigació, Cultura i Esport «Imágenes literarias de la diversidad: ciudadanía e identidad a través de la educación literaria», del Grup d’Investigació ELCiS: Educació Literària, Lingüística, Cultura i Societat.
Diversitat d’espais d’aprenentatge en rutes historicoartístiques i literàries per a l’alumnat d’Infantil i Primària a càrrec dels estudiants dels graus de Mestre
Authors: Rodrigo i Segura Francesc , Méndez Cabrera Jeroni , Asensi Silvestre Elvira
Published: September 2017

El projecte consisteix en la realització d’una ruta literària i historicoartística per la ciutat de València per a escolars per part dels estudiants dels graus de Mestre d’Educació Infantil i d’Educació Primària de Florida Universitària. En aquesta programació s’integren els objectius, els continguts i les competències específiques de Didàctica de les Ciències Socials i de Planificació de la Llengua i la Literatura. L’experiència s’ha realitzat en el curs 2014-2015 i hi han participat cinc grups de 4t curs. Des del paradigma de l’educació literària es considera que les rutes literàries són un recurs transversal d’un gran valor, ja que contemplen la interacció entre els espais urbans i el fet literari. Des de la Didàctica de les Ciències Socials s’aposta per traspassar els murs de l’escola i apropar-se a l’entorn urbà amb la finalitat de plantejar propostes problematitzades de «ciutat viscuda ». L’espai urbà es presenta com una experiència didàctica col·lectiva, en un entorn interdisciplinari d’aprenentatge. En el projecte s’aborden aspectes metodològics com l’enfocament globalitzador de les àrees curriculars en Educació Infantil, o el tractament integrat de llengua i contingut en Educació Primària; per poder programar aprenentatges no lingüístics (ciències socials) tot utilitzant el valencià com a llengua vehicular.
Ressenya d’En la pell del pacient, de Salvador Esquena (Ara Llibres, Barcelona, 2016, 184 pàgines)
Authors: Kotátková Adéla
Published: September 2017

Ressenya d’En la pell del pacient, de Salvador Esquena (Ara Llibres, Barcelona, 2016, 184 pàgines).
Contribution of legumes on phosphoric absorption by Panicum maximum cv Riversdale in intercropping system
Authors: . Sajimin , Purwantari Nurhayati D. , Sugoro Irawan
Published: September 2017

Phosphorus availability in soil as a mobile mineral influences forage growth. The purpose of doing this research is to enhance the soil phosphorus availability and grass production of Panicum maximum cv Riversdale by intercropping system with legums. The experiment was conducted based on with randomized design with five treatments of mixcropping of: (i) Gliricidia sepium + P. maximum; (ii) Calliandra calothyrsus + P. maximum; (iii) Leucaena leucocephala cv Taramba + P. maximum; (iv) Calopogonium mucunoides + P. maximum; (v) P. maximum as negative control. Plants were grown in pots with split-root technique using partition with a whole to allow some legume roots grew in the grass side. After growing for three months, on the legume areas 32P isotop solution was injected for 50 ml (11.23 μci/ml). After 21 days incubation samples were collected from both soil areas and both plants. The translocation of 32P was determined using geiger counter from legumes into the grass and the concentration of 32P was also determined in all plants. Forage productions was determined both in the legumes and grass. Result showed that soil phosphorus concentration in the grass area was significantly improved by intercropping with G. sepium and C. callothyrsus, while the one with L. leucocephala was similar, and the one with C. mucunoides was significantly lower than that of negative control (without legume). Detection of 32P showed that there was P translocation in the system. P. maximum grass production depending on kind of legumes (P<0.05) those with G. sepium was significantly higher, L. leucocephala and C. callothyrsus were not significantly higher, while the one with C. mucunoides was 26.2% lower from the control although not significantly. However, C. mucunoides produced the highest forage from the legume plant. It is concluded that grass-legume intercropping had a positive impact on phosphorus soil concentration in the grass area and grass production. Kind of legumes influenced the effectivity.
Vector Control of Zoonotic Arbovirus Disease in Indonesia
Authors: Ekawasti Fitrine , Martindah Eny
Published: September 2017

Zoonotic Arbovirus diseases which are caused by the genus of Flavivirus, Alphavirus, and Bunyavirus, are transmitted through potential vectors. These diseases are commonly occurred, especially in tropical countries, including Indonesia. They can affect the economic development because of the high morbidity and mortality. This paper describes the incidence of zoonotic Arbovirus in Indonesia and the strategy to control its vector. Factors that support the occurrence of zoonotic Arbovirus diseases are environmental, demographic and behavioral changes, as well as advanced technology, transportation and global trade. These diseases would not occur without the role of vectors. Vector control can be carried out effectively through longitudinal surveillance to identify types of potential vectors in the area. Therefore to prevent the increased incidence of the diseases, controlling the vector is necessary.
Sobre la crisis de la modernidad. Una lectura desde la perspectiva del arte
Authors: Malquori Diego
Published: September 2017

En este artículo se propone una reflexión sobre el arte como expresión de la redefinición de la cultura moderna. El arte, en efecto, expresa las líneas que definen el mundo, pero al mismo tiempo produce una diferente forma de verdad. Por ello un discurso sobre el arte no puede prescindir de un análisis del mundo en que este se origina y que de alguna forma intenta expresar. En esta dirección, se consideran tres lecturas de la cuestión de la modernidad: la Dialéctica de la Ilustración de Horkheimer y Adorno, La barbarie de Henry, y El fin de la modernidad de Vattimo. En la segunda parte, el discurso se centra en la manifestación de la crisis en el arte, intentando ofrecer otros sentidos, a partir de diferentes enfoques filosóficos, a la transición desde modernidad a posmodernidad.
Totalidad en arquitectura. Reflexiones sobre la estética y la coexistencia de las cosas con el lugar que producen en nosotros una experiencia de totalidad
Authors: Gallardo Frías Laura
Published: September 2017

Hoy en día es una revolución hablar de totalidad, —nos referiremos con este concepto a la cualidad de total, de cosa íntegra—, en un mundo tan fragmentado. ¿Dónde quedaron las enseñanzas de Vitrubio de considerar tantas cosas: el firmamento, el paisaje, las estrellas… y hoy: nuestras ciudades, sus habitantes, el contexto…? En este artículo se revisarán distintos autores procedentes de diferentes ámbitos del conocimiento que dialogan a través del tiempo, es decir, se sigue un orden en función de sus ideas, más que cronológico, que permitan una dialéctica sobre la importancia de la reflexión en los proyectos arquitectónicos más allá del objeto en sí mismo, para abrir la discusión sobre la consideración de otros aspectos relevantes que conduzcan a seguir pensando, proyectando la arquitectura con la finalidad de aspirar a generar un lugar y una experiencia de totalidad para sus habitantes.
Awareness raising about protection from sexual abuse in mild mental disabled children parents: Practice sample of an education; Hafif zihinsel engelli çocukların ebeveynlerinde çocuk cinsel istismari konusunda farkındalık yaratma: Eğitim uygulaması örneği
Authors: Küçük Sibel , Platin Nurgün , Erdem Emine
Published: September 2017

Increasing awareness of the mental disabled children and their families related to sexual abuse could help them in protecting from this experience. This study was conducted to conceive awareness about sexual abuse in mental disabled children families as experimental with pre-post test design. Fifteen mild mental disabled children parents were taken to the study. Data were collected with Parent Interview Form by the researcher. Education for the parents was given with Parents Education Guide Booklets and PowerPoint presentations in 6 sessions. Ethical institute assent and written consents of the parents were taken. For analysis number, percentage and Wilcoxon tests were used.Also, parents' general knowledge scores increase in all educational subjects. İt is determined that there was a statistical difference regarding to the parents’ scores of general knowledge about all education subjects between before and after the education (p<0.05).After the study; the awareness of mental disabled children parents about protecting from a possible sexual abuse were increased as desired with educations about protecting from sexual abuse.  Extended English abstract is in the end of PDF (TURKISH) file.ÖzetZihinsel engelli çocukların ailelerinin çocuk cinsel istismarı konusunda farkındalıklarının artması çocuklarının karşılaşabilecekleri olası bir cinsel istismar deneyiminden korunmaları konusunda yardımcı olabilir.Bu araştırma, zihinsel engelli çocukların ebeveynlerinde cinsel istismar konusunda farkındalık yaratmak amacıyla öntest-sontest yarı deneysel desende yapılmıştır. Araştırma 15 hafif zihinsel engelli çocuk sahip ebeveyn ile gerçekleştirilmiştir. Veriler Ebeveyn Görüşme Formu kullanılarak toplanmıştır. Eğitimler Ebeveyn Eğitimi Kılavuz Kitapçıkları ve Sunuları ile 6 eğitim oturumunda gerçekleştirilmiştir. Etik kurul onayı ve ebeveynlerden yazılı bilgilendirilmiş onam formu alınmıştır. Değerlendirmede sayı, yüzdelik ve Wilcoxon testi kullanılmıştır.Ebeveynlerin tüm eğitim konularında genel bilgi puanlarının arttığı ve eğitim öncesi ve sonrası arasında istatistiksel fark olduğu (p<0.05) belirlenmiştir.Araştırma sonucunda; zihinsel engelli çocukların ebeveynlerine verilen cinsel istismardan korunma eğitimleri ile olası bir cinsel istismardan korunmada farkındalıkları istendik yönde arttırılmıştır.
Toward a Yin-Yang Balancing Perspective of Relational (Guanxi) Gatekeeping in International Exchange Relationships in China
Authors: Gao Hongzhi , Ren Monica , Miao Qing
Published: September 2017

China is an extremely complex and “insider-controlled” market for foreign businesses. This study offers a yin-yang balancing perspective of international exchange relationships in China. The authors investigate how “relational gatekeepers” play a key role in achieving a dynamic balance between Western companies and local partners in international exchange relationships. In-depth interviews are conducted with 41 business managers based in China, Australia, and New Zealand. Guided by the yin-yang balancing frame, the authors develop four key constructs of relational gatekeeping: the gatekeeper resources of mianzi (insider status) and renqing (insider favor) and the gatekeeper capabilities of zao shi (creating favorable momentum) and ying shi (leveraging favorable momentum). The yin-yang frame provides a process view of business relationships that accepts paradoxical conditions and embraces dynamic network momentum, resources, and capabilities. The study concludes by showing the theoretical implications for network theory and for the field of dynamic balancing and suggests the managerial implications for an international company aiming to engage relational gatekeepers to break into insider (guanxi)-controlled local business networks.
Understanding the Importance of the Length of Global Product Rollout: An Examination in the Motion Picture Industry
Authors: Griffith David A. , Yalcinkaya Goksel , Rubera Gaia , Giannetti Verdiana
Published: September 2017

Employing the resource-based view of the firm and the competitive forces perspective, the authors examine how brand equity (star power, director power, and brand extensions), financial resources, and competitive intensity serve both as antecedents to the length of global product rollout and as moderators of the effect of length of global product rollout on global product performance. The results, based on data from the motion picture industry, demonstrate that brand equity, financial resources, and competitive intensity result in shorter global product rollout and that shorter global product rollout enhances global product performance. They also find that brand equity and financial resources operate as moderators, magnifying the effect of length of global product rollout on global product performance. Implications for international marketing academics and practitioners are presented.