bluuebunny/crossref_metadata_2025 huggingface dataset:
El fin del estilo paleolítico: un caso de estudio en el Noroeste peninsular
Authors: Mosquera Castro Tania , Santos André , Fábregas Valcarce Ramón , Rodríguez-Álvarez Xosé Pedro , De Lombera-Hermida Arturo
Published: December 2023

La consideración del Noroeste peninsular como un territorio marginal respecto de la distribución del arte paleolítico ha cambiado en los últimos tres decenios tras el hallazgo de diversas manifestaciones gráficas en soportes muebles o rupestres -tanto en ambientes cavernarios como al aire libre-. Algunas de las evidencias descubiertas se pueden adscribir a momentos terminales del Paleolítico, encuadrándose entre el Allerød y el Preboreal. Con el fin de profundizar en el conocimiento de este estadio gráfico, se estudia un conjunto de figuras zoomorfas adscritas a ese período, localizadas en Cova Eirós y el valle del Côa. El análisis morfológico y técnico de las representaciones permite identificar paralelismos y particularidades que constatan la existencia de convenciones y recursos gráficos compartidos, al tiempo que aporta nuevos datos acerca de las características de este episodio gráfico y las relaciones entre estos territorios en el Paleolítico superior final.
Understanding and mitigating water resource decline in the Deli watershed: a comprehensive analysis
Authors: Marselina Mariana , Hanie Meidina Zulfa , Nurhayati Siti Ai
Published: December 2023

In Indonesia, the common method for determining water resources' carrying capacity in an area has been the comparison of water availability and water demand. However, water resources' carrying capacity constitutes a complex system with interrelated variables that interact and influence one another. This study employs both the System Dynamics and the Analytic Hierarchy Process (AHP) approaches, which are subsequently integrated to develop an index that effectively represents the status of the water resources' carrying capacity, to investigate the water resources' carrying capacity in the Deli Watershed, one of the National Strategic River Regions and a raw water supplier for three cities/regencies in North Sumatera Province. The focus is on the quantity of water resources and designing scenarios to address challenges posed by economic and population growth that cause changes in land use. The results indicate that without intervention, the water resources' carrying capacity index declines, reaching a concerning status by 2038; however, integrated programs targeting birth and in-migration rates, domestic water use reduction, and land restoration can lead to a positive trajectory, emphasizing the unique integration of System Dynamics and AHP hold promise for sustainable water resources management practices.
Emodin is a Potential Drug Targeting CD44-positive Hepatocellular
Cancer
Authors: Gao Yuan , Li Youling , Zhu Yunhe , Luo Qiao , Lu Yifeng , Wen Ke , Du Boyu , Xi Xueyan , Li Gang
Published: December 2023

Background:

Liver cancer is one of the most prevalent forms of cancer of the digestive
system in our country. The most common subtype of this disease is hepatocellular carcinoma (HCC).
Currently, treatment options for HCC patients include surgical resection, liver transplantation,
radiofrequency ablation, chemoembolization, and biologic-targeted therapy. However, the efficacy
of these treatments is suboptimal, as they are prone to drug resistance, metastasis, spread, and
recurrence. These attributes are closely related to cancer stem cells (CSCs). Therefore, the utilization
of drugs targeting CSCs may effectively inhibit the development and recurrence of HCC.

Methods:

HepG2 and Huh7 cells were used to analyze the antitumor activity of emodin by quantifying
cell growth and metastasis, as well as to study its effect on stemness.

Results:

Emodin effectively suppressed the growth and movement of HCC cells. Emodin also significantly
inhibited the proliferation of CD44-positive hepatoma cells.

Conclusion:

Emodin shows promise as a potential therapeutic agent for HCC by targeting CD44--
positive hepatoma cells.
Galectin-3 in Blood Serum and Lymphocytes as a Marker of Myocardial
Damage in Patients with Arterial Hypertension and COVID-19
Authors: Pokrovska Nataliia , Denysenko Nataliia , Fomenko Iryna , Sklyarova Helen , Basylevych Andrii , Sklyarov Eugene , Vari Sandor G. , Kobylinska Lesya
Published: December 2023

Background::

The constant increase of arterial hypertension and the development of pathology at an earlier age are global healthcare problems that cause damage to vital organs and worsen patient prognosis. In recent years, studies have shown that galectin-3 plays a role in the development and progression of arterial hypertension and coronavirus disease (COVID-19).

Objective::

The explanatory research study aimed to analyze the prognostic value of galectin-3 de-termination in the serum blood and lymphocytes of patients with arterial hypertension and corona-virus disease (COVID-19).

Methods::

The patients were divided into two groups: Group 1 consisted of 36 individuals with AH, Group 2 included 35 patients with arterial hypertension and polysegmental COVID-19 pneumonia, and 16 practically healthy individuals were included in the control group. All patients underwent anthropometry, biochemical blood analysis, determination of galectin-3, level in serum and lym-phocytes, IL-1β, IL-6, and echocardiography.

Results::

The highest level of galectin-3 was found in patients of Group 1, while in patients of Group 2, the concentration of galectin-3 was significantly decreased, mostly due to the treatment of COVID-19, in addition to prolonged antihypertensive therapy.

Conclusion::

The level of galectin-3 in serum and lymphocytes was significantly higher in patients of both groups compared to the control group (p<0.05). Arterial hypertension causes structural changes in the cardiovascular system that are associated with elevated levels of galectin-3 in serum and lymphocytes. It can be used as a marker of myocardial damage in the context of arterial hyper-tension and COVID-19.
In silico Evaluation of ACE2 Inhibition by Prunus armeniaca L. and in vivo
Toxicity Study
Authors: Bouadid Ismail , Moujane Soumia , Akdad Mourad , Benaissa Moualij , Eddouks Mohamed
Published: December 2023

Background:

SARS-CoV-2 is a virus that uses ACE2 to enter the host cell

Aims and Objectives:

This study aimed to evaluate the in silico inhibitory activity of polyphenols
from Prunus armeniaca (P. armeniaca) on angiotensin-converting enzyme 2 (ACE2).

Methods:

The efficacy of phytocompounds from P. armeniaca in inhibiting ACE2 was tested
through molecular docking and dynamic analyses. The toxicological analysis of P. armeniaca
was also evaluated.

Results:

total of twenty polyphenols were docked against the ACE2 active site, and four compounds
showed interesting profiles. In vivo acute toxicity study demonstrated that the aqueous
extract of Prunus armeniaca was safe.

Conclusion:

Four compounds from Prunus armeniaca seem to exert an inhibitory potential of
ACE2
Evaluation of Bio-inspired Computational Methods for Measuring Cognitive Workload
Authors: Kapila Vani R. K. , Padmanabhan Jayashree
Published: December 2023

Evaluating mental workload is crucial to preserve health and prevent
mishaps. The reliability and mental states of individuals in any human-computer
interaction scenario are assessed utilizing features of the electroencephalogram (EEG)
by means of many approaches in machine learning and deep learning This study
reviews and identifies the multiple Machine Learning and Deep Learning algorithms
used for workload assessment, as well as the various datasets, characteristics, and
features that contribute to workload assessment. When ML and DL approaches were
compared, it was found that deep learning techniques and ensemble techniques work
best when EEG's Power Spectral Density Features are used. We have also used
optimization techniques like GWO and taken into account numerous features from
various domains and assessed the workload. This study discovered that when
measuring cognitive load, features like PSD were employed and deep learning
algorithms were applied if algorithm performance was crucial. However, when
accuracy was valued more highly, all features were taken into account and only a small
subset of them was chosen using optimization techniques. The latter method was found
to be more accurate and reliable than the methods currently in use.
Biometric Voting using IoT to Transfer Vote to Centralized System: A Bibliometric
Authors: Essah Richard , Anand Darpan , Singh Surender , Senior Ampofo Isaac Atta
Published: December 2023

Several studies have empirically explored biometric voting using the IoT to
transfer votes to the central system. There aren't many bibliometric studies that
categorize the output in this area, though. By keeping an eye on the papers posted on
the Scopus platform, this study’s goal is to present a research bibliometric analysis of
biometric voting utilizing IoT to transfer votes to a central system, classifying trends,
the state of the art, and other indications. 267 different materials made up the sample.
Using the VOS viewer program, the data was processed and the outcomes graphically
represented. According to a study, that examined publications’ simultaneous
occurrence by year, trends of keyword, co-citations, coupling bibliographic, and coauthorship analysis, institutions, and countries, the body of knowledge on biometric
voting that uses the Internet of Things to transfer votes to a central system is expanding
quickly. More than 530 citations were found in just eight works. However, there are
other industrious writers. The most significant of the 267 sources used in the review
were published in 26.066 percent of the papers. China is the world's leader in this field.
This study offers knowledge about the current state of the art and indicates research
opportunities and gaps in IoT-based biometric voting.
Multimedia Security in Audio Signal
Authors: Diwaker Ritesh , Asrani Deepak
Published: December 2023

The security of Digital media has been varying continuously due to
advanced malware attacks. Multimedia security has become one of the major concerns
since new technologies are introduced. The proposed paper applied the watermarking
technique in digital audio signals in which unique data is inserted in one-dimensional
data in such a way that it must not affect the major information of the audio signal. The
hybrid decomposition scheme has been applied to the audio data in order to extract
features in terms of energy bands. The data is kept hidden in a low significant energy
band that contains less information. This watermarking technique ensures the
ownership of the multimedia data. Only authorized authors can be able to claim
ownership of the audio data. The correct authorization of audio data can be proven by
the extraction method in which the hidden watermark data has been extracted back to
its original form without leaving any distortion in audio data. The proposed work
introduces a hybrid approach to watermarking 2D data into an audio file. A hybrid
audio decomposition technique was introduced by the proposed scheme in which a dual
form of audio decomposition method has been applied containing Fast Fourier
transform (FFT) and Cordic QR scheme. The correct location from the energy band has
been found to embed the watermark data. Before the embedding procedure, the
watermarking data has been selected. The proposed method selects an image
containing information as a watermark that is first encrypted before initiating the
embedding process. Watermark Encryption has been done using a cyclic coding
algorithm and Arnold’s cat map. The disintegration of the audio file will finally result
in Q and R matrices. Both such matrices are of orthogonal type. Then, the encrypted
watermark data has been implanted in a random fashion in the R component of
decomposed audio data during the embedding process. The inverse procedure has been
applied for the watermark extraction and decryption process.
Animal-Based Biochar Reinforced Polymer Composites
Authors: Mandala Radhika , Anjaneya Prasad B. , Akella Suresh
Published: December 2023

Biomass-derived waste management has become an increasingly pressing
concern due to rising levels of environmental issues. As a result, interest has risen in
finding ways to turn biomass wastes into useful products. The conversion of biowaste
into biochar is one of the efficient and environmentally friendly methods of disposing
of biowaste. Developing polymer composites by reinforcing biochar as the filler
material is gaining popularity due to their affordability and exceptional thermal and
mechanical properties. Animal waste is one of the biomass wastes that can be
converted into biochar and can be used in various applications. This review work
aimed at synthesizing biochar from animal wastes, preparing polymer composites, and
analyzing the thermo-mechanical properties. This review also focuses on various
animal feedstocks for the synthesis of biocarbon and methods to fabricate polymer
composites. The biocarbon-induced polymer composites showed an improvement in
mechanical and thermal properties with varying percentages of loading.
The Application of Biocarbon Polymer Nanocomposites as Filaments in the FDM Process – A Short Review
Authors: Balasubramaniyan Singaravel , Thiruchinapalli Niranjan , Umesh Kankrej Rutika
Published: December 2023

Fused Deposition Modeling (FDM) is a solid-based 3D printing process. It is
one of the additive manufacturing technologies that is used to create a threedimensional (3D) object using a CAD model. In the FDM process, raw material also
known as filament, is initially in the solid state. Nowadays, biocarbon-incorporated
polymer-based nanocomposite is used as a filament in the FDM process, due to the
enhanced strength of the base polymer. In this paper, a review of carbon extracted from
natural waste, such as tea powder, coffee grounds, egg shells, ocean plastic, coconut
shells, etc., is presented The extraction procedure of biocarbon is given in detail. The
results indicate that the strength enhancement of polymers can be achieved by
incorporation of derived carbon from industry as well as agriculture waste. In addition,
biocarbon-based polymer nanocomposite filaments in the FDM process can be
developed by reinforcing the polymer matrix with carbon nanoparticles. Future work of
this review process will explore the biobased carbon from various waste resources. The
application of biocarbon-based polymer nanocomposites for the 3D printing process is
highlighted.
Tensile Characteristics of FDM 3D Printed PBAT/PLA/Carbonaceous Biocomposites
Authors: Souza Gustavo F. , Oliveira Rene R. , Barros Janetty J.P. , Almeida Fernando L. , Moura Esperidiana A.B.
Published: December 2023

The use of carbonaceous fillers in polymeric biocomposite materials has
been widely studied due to their potential to add better engineering properties to
biocomposites and expand their field of applications. Currently, due to the growing
global concerns over environmental pollution and climate change, carbonaceous fillers
derived from biomass are the preferred choice for production of the sustainable
biocomposite materials. Rice husk ash (RHA), an abundant and sustainable
carbonaceous filler obtained from the burn of rice husk in kilns of the processing rice
was incorporated into the PBAT/PLA blend. The influence of RHA loading on the
tensile properties of FDM-3D printed samples was investigated. Neat PBAT/PLA
filament and its biocomposite filaments with 2.5, 5.0 and 7.5 wt. % RHA were
prepared by the extrusion process. The filaments were characterized by FTIR, TG, and
SEM. FDM-3D printed specimens were subjected to tensile tests.
Energielandschap op mensenmaat
Authors: van Weerdenburg Demi , Vandevoorde Jakob
Published: December 2023

Om de noodzakelijke energietransitie te versnellen, maken steeds meer Vlaamse regio's gebruik van burgerpanels als lokale experts. In samenspraak met deze panels tracht men op regionaal niveau aan gebiedsgerichte energieplanning te doen, en zo niet alleen energieproductie en uitstoot te reguleren, maar ook de ruimtelijke en landschappelijke implicaties van hernieuwbare energie met een grotere groep actoren te bespreken en ontwerpen.
De verlokkingen van data en het maatschappelijke belang
Authors: Klingenberg Aline
Published: December 2023

Maatschappelijk functioneren zonder data achter te laten is niet meer mogelijk. Deze data worden gretig gebruikt door bedrijven en de overheid. Of om geld mee te verdienen of om maatschappelijke doelen mee te bereiken. Maar wanneer gaat dit te ver? Wanneer komen we tot de conclusie dat er veel te veel data door bedrijven en overheden gebruikt worden en dat er geen enkel moment is waarop je onbewaakt je gang kan gaan? Met name nu onze data ook gebruikt gaan worden voor de ontwikkeling van AI liggen ongelukken op de loer. Juist daarom moeten bedrijven en overheden veel meer doen om te voorkomen dat een ‘digitale extinction rebellion’ over een aantal jaren nodig is. Hierover vertelt Aline Klingenberg in haar oratie op 6 oktober 2023. Bedrijven moeten zich bij het gebruik van data van personen niet slechts door commerciële belangen laten leiden, het maatschappelijke belang moet een zware rol krijgen. Hier ligt een rol voor de toezichthouder en de rechter. De overheid kan dat al, als ze wil. Bij het beoordelen van de rechtmatigheid van een verwerking van persoonsgegevens kan de overheid nu al kijken naar de optelsom van het totaal van verwerkingen: wordt dit allemaal niet veel te veel? Dit geldt ook voor de maatschappij in het klein die de RUG vormt. In het onderwijs bijvoorbeeld wordt elke stap die studenten op de digitale leeromgeving zetten gevolgd. Maar moeten we bij het academisch onderwijs niet juist de vrije discussie en gedachtenvorming vooropzetten en moet daarom nu niet juist het ‘digitale schoolplein’ van de RUG vrij zijn van het volgen van studenten? Het recht loopt altijd achter maatschappelijke ontwikkelingen aan. In deze tijd vragen grote vraagstukken om een oplossing. Data kunnen daar een rol in spelen. Het gaat om de vraag hoe dit op een verantwoorde manier voor elkaar te krijgen.
Pedagogical mentoring in virtual exchange: Developing students’ videoconferencing skills
Authors: Pintado Gutiérrez Lucía , F. Gutiérrez Begoña , Gómez Soler Inmaculada
Published: December 2023

In the context of foreign language education (FLE), virtual exchanges (VE) involving videoconferencing are becoming an increasingly widespread practice. It is to be expected that students face challenges as they may not have developed the skills necessary to successfully carry out these types of online intercultural interactions naturally. In order for them to get the most out of the collaborative learning experience, teachers must engage in the process of teaching students how to do so. With this in mind, this case study analyses the impact that VE teachers’ mentoring had on the development of students’ videoconferencing skills by conducting a qualitative content analysis of pre- and post-intervention videoconference recordings, as well as students’ reflections in their personal portfolios. Despite the limitations identified, the results of this study point to the importance of providing adequate videoconferencing mentoring to improve the VE learning experience and its learning outcomes.
Estudio de la cinética de secado del maíz suave (Zea mays L) variedad Guagal (INIAP 111)
Authors: García-Culqui Roxana , Guevara-Narváez Lady , Verdezoto-Mendoza Franz , Gaibor-Chávez Juan
Published: December 2023

El objetivo fue determinar la cinética de secado del maíz (Zea mays L), variedad Guagal mejorado. Se realizaron con tres muestras de materia prima a temperaturas no controladas entre 60 °C – 80 °C durante 12 horas, seguido por el proceso de cinética de secado en una estufa a 104°C durante 24 horas. Las muestras iniciaron con pesos de 8.09 g; 10.02 g; 11.16 g respectivamente con una humedad inicial de 22.13 % y se obtuvo una humedad final de 0,53 %; 0,7 %; 0,61 %. Las variables medidas incluyeron la humedad en base seca, total y en equilibrio, el flujo de calor, la cantidad y la eficiencia de calor, y la velocidad de secado. Se determinó que la velocidad de secado a mayores temperaturas favorece a la transferencia de masa y energía. Se estableció que el modelo de Henderson y Pabis fue el que mejor se adaptó a los datos experimentales obtenidos en el proceso de cinética de secado a 104°C por 24 horas R2 = 99,798%; mientras que el modelo de Page fue el que mejor se adaptó a los datos obtenidos durante la deshidratación a 60-80°C durante 12 horas R2 = 99,881 %. Esto sugiere que se pueden obtener mejores resultados de secado y deshidratación con la variedad de maíz INIAP 111 Guagal mejorado si se considera el establecimiento de la temperatura adecuada y el tiempo de procesamiento.

Palabras clave: Cinética, secado, maíz, modelo matemático, harina de maíz.
Estudio de cinética de fermentación alcohólica de cacao en cajón tipo madera
Authors: García María Eugenia , Pazmiño Vallejo Rommel Aaron , Troya Carrera Dayana Belén , Gaibor Chávez Juan
Published: December 2023

La investigación se enfocó en valorar la influencia de fermentadores en cajones de madera: Guayacán (Tabebuia Chrysantha), Laurel (Laurus nobilis), y Caña (Guadua angustifolia) sobre la calidad fisicoquímicas de las almendras de cacao (Theobroma cacao L.). Se aplicó un diseño AXB con arreglo factorial (2x3) y se determinó el porcentaje de fermentación en los tres tipos de cajas visualizando el 60 % mínimo de almendras bien fermentadas, granos violetas 21 %, granos pizarrosos superó el 12 %, lograr las mejores características organolépticas en el grano de cacao resultante, implica un adecuado tratamiento, mejores prácticas aplicadas y la incorporación de un tipo de fermentador que garantice el éxito del proceso.

Cabe señalar que el primer proceso se ve afectado por varios factores tales como: tipo de madera a utilizar para la construcción de los cajones, dimensiones de estos, el tamaño de los orificios que permiten la evacuación del mucilago y las remociones que se le dé a la masa durante el proceso. El proceso fermentativo se convierte en el principal proceso del beneficio pues los cambios que se originan son fundamentales para que aparezcan los agentes precursores del aroma y sabor típicos del cacao de calidad. Es por eso por lo que se ha utilizado un modelo matemático para poder determinar datos importantes en la fermentación alcohólica que se realiza en las cajas. Dicho de esta manera se aplica una modelación matemática para la fermentación de Cacao (Theobroma cacao L.), para la cinética correspondiente, el comportamiento de la biomasa con el consumo de sustrato y el comportamiento del sustrato y Crecimiento microbiano por medio de los modelos matemáticos de Monod y de Andrews y Levenspiel.

Palabras clave: Crecimiento Microbiano, Fermentación Alcohólica, Mucilago, Madera, Matemáticas Modelos.
Variabilidad de actividades enzimáticas en suelos arenosos de playas del Municipio Puerto Cabello, Estado Carabobo, Venezuela
Authors: Albujar Joselin , Armado Arnaldo , Briceño Jorge , Avalos Daniela , Salazar Sonia , Rojas Marcelo
Published: December 2023

Los ecosistemas costeros reciben impactos negativos por actividades industriales, explotación de especies costeras, actividades turísticas y recreativas, lo que hace necesario evaluar su calidad ambiental. El objetivo de este trabajo fue estudiar la variabilidad de las actividades enzimáticas de catalasa, ureasa y proteasa en suelos arenosos de playas del municipio Puerto Cabello, estado Carabobo para su uso como indicadores de calidad ambiental. Las playas estudiadas fueron El Palito (EP), Waikiki (W) y Playa Blanca (PB). Se establecieron cuatro unidades de muestreo: zona lejana (L), zona cercana (C), zona seca (S), zona húmeda (H), tomando muestras superficiales (s) y sub-superficiales (ss) en época lluviosa y seca. Se determinaron parámetros fisicoquímicos y las actividades enzimáticas de catalasa, ureasa y proteasa. La actividad de catalasa, muestra variabilidad asociada a las zonas evaluadas, pero no se evidencian variaciones estacionales. La actividad de ureasa, refleja una variabilidad con respecto a las zonas de la playa y la fuente contaminante; mientras que la actividad proteasa no muestra variación estacional, pero si respecto a las zonas de la playa y la fuente contaminante. Se evidenció una correlación negativa significativa entre la actividad catalasa y el contenido de arena, retención de humedad, materia orgánica y una correlación positiva entre la actividad de la ureasa y el contenido de materia orgánica. Finalmente, se concluye que las actividades enzimáticas de catalasa, ureasa y proteasa son sensibles ante impactos antropogénicos, por lo que pueden ser usadas como indicadores de calidad en los suelos arenosos evaluados.

Palabras clave: Catalasa; indicadores de calidad de suelo; proteasa; suelos arenosos; ureasa.
Performance Test of a Well-Trained Model for Meningioma Segmentation in Health Care Centers: Secondary Analysis Based on Four Retrospective Multicenter Data Sets
Authors: Chen Chaoyue , Teng Yuen , Tan Shuo , Wang Zizhou , Zhang Lei , Xu Jianguo
Published: December 2023

Background

Convolutional neural networks (CNNs) have produced state-of-the-art results in meningioma segmentation on magnetic resonance imaging (MRI). However, images obtained from different institutions, protocols, or scanners may show significant domain shift, leading to performance degradation and challenging model deployment in real clinical scenarios.

Objective

This research aims to investigate the realistic performance of a well-trained meningioma segmentation model when deployed across different health care centers and verify the methods to enhance its generalization.

Methods

This study was performed in four centers. A total of 606 patients with 606 MRIs were enrolled between January 2015 and December 2021. Manual segmentations, determined through consensus readings by neuroradiologists, were used as the ground truth mask. The model was previously trained using a standard supervised CNN called Deeplab V3+ and was deployed and tested separately in four health care centers. To determine the appropriate approach to mitigating the observed performance degradation, two methods were used: unsupervised domain adaptation and supervised retraining.

Results

The trained model showed a state-of-the-art performance in tumor segmentation in two health care institutions, with a Dice ratio of 0.887 (SD 0.108, 95% CI 0.903-0.925) in center A and a Dice ratio of 0.874 (SD 0.800, 95% CI 0.854-0.894) in center B. Whereas in the other health care institutions, the performance declined, with Dice ratios of 0.631 (SD 0.157, 95% CI 0.556-0.707) in center C and 0.649 (SD 0.187, 95% CI 0.566-0.732) in center D, as they obtained the MRI using different scanning protocols. The unsupervised domain adaptation showed a significant improvement in performance scores, with Dice ratios of 0.842 (SD 0.073, 95% CI 0.820-0.864) in center C and 0.855 (SD 0.097, 95% CI 0.826-0.886) in center D. Nonetheless, it did not overperform the supervised retraining, which achieved Dice ratios of 0.899 (SD 0.026, 95% CI 0.889-0.906) in center C and 0.886 (SD 0.046, 95% CI 0.870-0.903) in center D.

Conclusions

Deploying the trained CNN model in different health care institutions may show significant performance degradation due to the domain shift of MRIs. Under this circumstance, the use of unsupervised domain adaptation or supervised retraining should be considered, taking into account the balance between clinical requirements, model performance, and the size of the available data.
Examining Human-Smartphone Interaction as a Proxy for Circadian Rhythm in Patients With Insomnia: Cross-Sectional Study (Preprint)
Authors: Lin Chen , Chen I-Ming , Chuang Hai-Hua , Wang Zih-Wen , Lin Hsiao-Han , Lin Yu-Hsuan
Published: December 2023

BACKGROUND

The sleep and circadian rhythm patterns associated with smartphone use, which are influenced by mental activities, might be closely linked to sleep quality and depressive symptoms, similar to the conventional actigraphy-based assessments of physical activity.

OBJECTIVE

The primary objective of this study was to develop app-defined circadian rhythm and sleep indicators and compare them with actigraphy-derived measures. Additionally, we aimed to explore the clinical correlations of these indicators in individuals with insomnia and healthy controls.

METHODS

The mobile app “Rhythm” was developed to record smartphone use time stamps and calculate circadian rhythms in 33 patients with insomnia and 33 age- and gender-matched healthy controls, totaling 2097 person-days. Simultaneously, we used standard actigraphy to quantify participants’ sleep-wake cycles. Sleep indicators included sleep onset, wake time (WT), wake after sleep onset (WASO), and the number of awakenings (NAWK). Circadian rhythm metrics quantified the relative amplitude, interdaily stability, and intradaily variability based on either smartphone use or physical activity data.

RESULTS

Comparisons between app-defined and actigraphy-defined sleep onsets, WTs, total sleep times, and NAWK did not reveal any significant differences (all P>.05). Both app-defined and actigraphy-defined sleep indicators successfully captured clinical features of insomnia, indicating prolonged WASO, increased NAWK, and delayed sleep onset and WT in patients with insomnia compared with healthy controls. The Pittsburgh Sleep Quality Index scores were positively correlated with WASO and NAWK, regardless of whether they were measured by the app or actigraphy. Depressive symptom scores were positively correlated with app-defined intradaily variability (β=9.786, SD 3.756; P=.01) and negatively correlated with actigraphy-based relative amplitude (β=–21.693, SD 8.214; P=.01), indicating disrupted circadian rhythmicity in individuals with depression. However, depressive symptom scores were negatively correlated with actigraphy-based intradaily variability (β=–7.877, SD 3.110; P=.01) and not significantly correlated with app-defined relative amplitude (β=–3.859, SD 12.352; P=.76).

CONCLUSIONS

This study highlights the potential of smartphone-derived sleep and circadian rhythms as digital biomarkers, complementing standard actigraphy indicators. Although significant correlations with clinical manifestations of insomnia were observed, limitations in the evidence and the need for further research on predictive utility should be considered. Nonetheless, smartphone data hold promise for enhancing sleep monitoring and mental health assessments in digital health research.
Snowball Group Usability Testing: a novel method for pragmatic multi-site testing (Preprint)
Authors: Dauber-Decker Katherine L , Feldstein David , Hess Rachel , Mann Devin , Kim Eun Ji , Gautam-Goyal Pranisha , Solomon Jeffrey , Khan Sundas , Malik Fatima , Xu Lynn , Huffman Ainsley , Smith Paul D , Halm Wendy , Yuroff Alice , Richardson Safiya
Published: December 2023

BACKGROUND

Usability testing is valuable for assessing a new tool or system’s usefulness and ease-of-use. However, during clinical decision support (CDS) tool development, usability testing is often not done due to its time- and labor-intensiveness, cost, and the skills required to conduct the testing.

OBJECTIVE

Our objective was to develop a new method of usability testing that would enable efficient acquisition and dissemination of results among multiple institutions.

METHODS

We combined individual think aloud testing and focus groups into one session, and performed sessions serially across four institutions (Snowball Group Usability Testing) to assess the usability of two clinical decision support tools for use by nurses in the primary and urgent care settings.

RESULTS

The group testing and snowballing components of our new usability testing method proved to be highly beneficial. Study teams were more easily able to notice similarities in feedback among participants, and thus, to discuss and act upon suggestions efficiently, as feedback from multiple participants was obtained in a single session. Snowballing allowed study teams to incorporate feedback based on previous institutions’ sessions prior to conducting their own testing.

CONCLUSIONS

Snowball Group Usability Testing provides an efficient method of obtaining feedback on newly developed tools and systems, while addressing barriers typically associated with traditional usability testing methods. This method can be applied to test a wide variety of tools, including CDS tools, prior to launch so that they can be efficiently optimized, ultimately leading to higher adoption.

CLINICALTRIAL

NCT04255303
Kerajinan Memayet Perempuan Dayak Pampang sebagai Bentuk Penguatan Budaya terhadap Ekonomi Keluarga
Authors: Kurniati Nabillah , Arif Syaiful
Published: December 2023

This study aims to convey that Pampang Dayak traditional women with carving crafts have cultural awareness. Women who are often misunderstood can only have power in domestic affairs. In fact, women or like men have the same freedom of choice and responsibility. Customary regulations are often seen as a form of shackles to women's self-freedom. However, when the customary system has elements of gender justice in the division of tasks between men and women, a powerful customary social order will be formed. The method used by the author is ethnography, through an empirical approach by interviewing Dayak bead craftsmen. The results of the study show that the creativity and productivity of Pampang Dayak women have succeeded in empowering and strengthening the economy for their families. The great opportunity for economic turnover through the cultural tourism sector is well read by Pampang Dayak women, both in making crafts and traditional banquets. The movement of the family economy and traditional tourism festivals will have a rotational impact on the culture of the Pampang Dayak Village to further develop
Interpreting the Temporal Ideas in Das Kapital and Their Contemporary Implications
Authors: Zhao Yanling
Published: December 2023

In contemporary society, technological advancements have continuously enhanced social productivity. However, the progress of capital logic and the forceful competition mechanisms have imposed a severe sense of time urgency on individuals. Simultaneously, within limited leisure time, people find themselves ensnared in the consumption trap constructed by capital. Time has gradually lost its orderly rhythm and narrative tension, atomizing into scattered points without any inherent support. Once connected to nature and human essence, time has now undergone a complete rupture from these factors under the reshaping influence of capital, becoming the chain that firmly locks workers within the framework of capital production. Drawing on the rational aspects of both old materialist and idealist perspectives on time, Marx revolutionarily linked time to practice and material production activities, bringing about a transformative shift in temporal thinking. In Das Kapital utilizing time as a crucial key, he exposes the true nature of the bourgeoisie and calls upon the proletariat to embrace class consciousness, undertake their historical mission, and strive for a communist society where free time universally prevails. A thorough examination of Marx’s temporal ideas in Das Kapital and their integration with contemporary realities can provide valuable guidance for overcoming the temporal challenges faced by modern society.
Challenging the Market: The Future of Hybrid Gasoline-Electric Vehicles in Nueva Ecija
Authors: D. Gutierrez Ryan Rose , Guzman Levy DG. De , R. Lazatin Maurine , Lamson June Christian , E. Miranda Jhamaica , B. Agustin Noel
Published: December 2023

This descriptive research investigated the future of Hybrid Gasoline-Electric vehicles in the province of Nueva Ecija through awareness and buying motivations for the product. The research identified the level of perception of the prospective car buyers and their respective buying considerations in getting Hybrid Gasoline-Electric vehicles. The study employs a mixed-methods approach, including a survey and internet searches on several studies of Hybrid vehicles and several online platforms. The data revealed that there is no significant disparity between knowledgeable buyers and those who are oblivious to Hybrid Gasoline-Electric automobiles. The study also found that when purchasing a Hybrid Gasoline-Electric vehicle, there are important factors to consider regarding the product itself. However, these considerations are not adequately emphasized due to a lack of reliable information from the manufacturer. As a result, many customers rely on information provided by sales representatives and the Internet. Moreover, the study revealed some factors and advantages of the product that receive less emphasis in marketing but can significantly influence the purchasing decisions of purchasers in this particular vehicle class. The study recommends that automakers and their sales representatives focus on the most crucial quality aspects and allocate resources towards customer education and communication. This would help establish trust in the product and foster brand loyalty among customers in Nueva Ecija.
Validación y adaptación de una lista de chequeo para evaluar las prácticas de inyecciones seguras
Authors: Gaitán-Gómez O.L. , Bueno-Robles L.S. , Martínez-Reyes J.A.
Published: December 2023

Introducción: Las prácticas de inyección segura son un conjunto de acciones orientadas a preservar la esterilidad de los líquidos y medicamentos, disminuir el riesgo de punción del personal sanitario y evitar la eliminación de los dispositivos de inyección de manera inadecuada.
Objetivos: Adaptar y validar el instrumento Revised injection safety assessment tool (Tool C– Revised) para ser utilizada en la población colombiana.
Metodología: Estudio metodológico que comprendió la adaptación cultural, validación de apariencia y contenido (modelo de Lawshe modificado) de un instrumento que mide los atributos de la práctica de inyección segura, realizada entre junio del 2018 y enero del 2019.
Resultados: Esta adaptación resultó en la reducción de 73 a 42 ítems distribuidos en tres secciones: Observaciones de las instituciones, compuesta por 13 ítems; Observaciones práctica de la inyección; y Observaciones de flebotomías conformada por 29 ítems. De todos los ítems se mejoró la redacción de 20, se fusionaron 28 y se la eliminaron 11 debido a que no aplicabanal sistema de salud colombiano.
Discusión y Conclusión: La lista de chequeo se conformó con 42 ítems calificados como 100 % claros, precisos y comprensibles, además de ser esenciales para el instrumento según el modelo de Lawshe modificado. Estos hallazgos dan a conocer un instrumento validado al español que permite corroborar la ejecución de las buenas prácticas en la inyección,complementar los correctos al preparar y administrar medicamentos e incrementar los indicadoresde calidad en la atención en salud.
Producción científica en revistas mexicanas de enfermería: análisis descriptivo y bibliométrico del periodo 2016-2020
Authors: Landeros-Olvera E. , Ramírez-Girón N. , Galicia-Aguilar R.M. , Alba-Alba C. , Lozada-Perezmitre E. , Rodríguez-Hernández M.J.
Published: December 2023

Introducción: Los análisis bibliométricos de la producción de conocimiento en enfermería han permitido mostrar la evolución de temáticas específicas. Por ello, se requiere de una métrica que facilite la organización y categorización para mostrar áreas de oportunidad y mejorar la calidad de la investigación.
Objetivo: Describir las temáticas y características metodológicas de la investigación en enfermería publicada en revistas mexicanas a través de un análisis bibliométrico.
Metodología: Estudio ex post facto retrospectivo y bibliométrico. Se analizaron 354 artículos originales por medio de los siguientes indicadores: análisis descriptivo y de la productividad, de colaboración, metodológico y temático-conceptual.
Resultados: Se obtuvieron 354 artículos escritos por 1194 autores, con índices de Zakutina y Priyenikova 34.06, Lawani 3.94 y Subramanyam 0.987, tasa de autoría endógena de 29 %. El 43.5 % de las investigaciones se realizaron en áreas hospitalarias, enfocadas preferentemente al cuidado en cronicidad y adultos mayores. En los estudios cuantitativos predominaron los diseños descriptivos y transversales; más del 90 % no indicaron financiamiento. Entre los estudios cualitativos, el diseño fenomenológico tuvo mayor preferencia, la entrevista audiograbada fue la principal herramienta de indagación y en el nivel de análisis destacó la codificación abierta.
Discusión y conclusiones: Se identifica un incremento de producción científica en el primer nivel de atención con relación a estudios anteriores; sin embargo, predomina la investigación sobre temas clínico-hospitalarios. El uso de los indicadores bibliométricos representa una aproximación inédita a las características de las publicaciones de investigación en las revistas de enfermería mexicanas.
La caída de Tales o la resistencia paródica
Authors: García de Vicuña Gortazar Harriet
Published: December 2023

Este texto propone una reflexión sobre la paradójica resistencia de la filosofía a los intentos de definición que tratan de limitarla. En el escrito se utiliza el concepto de parodia, tal como Giorgio Agamben lo analiza, para pensar sobre las llamativas incongruencias en las que cae (probablemente busca y asume) la filosofía al pensar nuevos problemas que nada tienen que ver con los asuntos que la tradición consagra. La recurrente acogida de lo “nuevo” por los “viejos” métodos de la filosofía transforma el saber filosófico en un ejercicio “incoherente”, paródico, que se resiste, de manera tenaz, a aceptar cualquier definición que tenga la pretensión de fijar su labor de una vez por todas. La resistencia a la definición de la práctica del filosofar contrasta con los intentos de delimitación que, desde los más variados ámbitos, ha tenido que padecer el saber filosófico a lo largo de su historia: los testimonios y relatos que se hacen eco de la anécdota de la caída de Tales de Mileto (suceso que se utiliza como metáfora de la tendencia filosófica a la incongruencia, de ejemplo de práctica novedosa y por tanto incoherente) muestran la tensión en la que la filosofía ejerce su labor; los reproches y recriminaciones, los elogios y alabanzas que recibe el milesio revelan las pasiones encontradas que se desatan a la hora de tratar de nombrar al saber del primero de los filósofos. Colaborar en la reflexión sobre la (no)conformación de este paradójico espacio de pensamiento es la intención que ha motivado la escritura de este texto.
The addition of humic substances extracted from vermicompost enhances the growth performance and the antioxidant status of weaning pigs
Authors: Jonathan Alexander Agredo-Palechor , Gomez-Rosales Sergio , Angeles María de Lourdes , Pérez Alvarado María Alejandra , López-Hernández Luis Humberto , Mariscal-Landín Gerardo , Mendoza-Elvira Susana Elisa
Published: December 2023

The aim of the study was to assess the effect of humic substances (HS) extracted from vermicompost on the growth performance, fecal score, bone ash content and antioxidant status in muscles and blood serum of weaned pigs from 1-42 days postweaning. Two-hundred 22-day weaned pigs were assigned to four treatments: 1= Positive control diet with colistin (PC), 2= Negative control diet without antibiotic or HS (NC), 3 and 4= Diets with 2 500 and 5 000 ppm of HS, respectively. Growth performance, fecal consistency, dry matter and ashes of metatarsus and the 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, iron reducing ability and thiobarbituric acid reactive substances in muscles and blood were registered. Results were subjected to ANOVA and regression analysis. Linear increasing responses (P < 0.05) were found in the body weight at 42 days postweaning, the ADG from 1-7, 8-21, 22-42 and 1-42 and the gain:feed ratio from 1-7, 22-42 and 1-42 days postweaning, whilst the fecal score decreased linearly (P < 0.01) from 1-7, 8-21 and 1-42 days postweaning due to the increasing dietary HS concentration. The antioxidant potential of 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity (P < 0.05) in loin muscle and blood serum at three and seven days, and in fillet muscle at seven days postweaning increased linearly due to the increasing dietary HS concentration. It is concluded that the addition of HS improved the growth performance from 1-42 days postweaning and the antioxidant status in muscles and blood serum of weaned pigs at three and seven days postweaning.
Interpretation of Regional Geophysical Data Acquired at the Bathurst Mining Camp, Canada
Authors: Martinez Bustamante Juan Ignacio , Nitescu Bogdan
Published: December 2023

The Bathurst Mining Camp is a major base-metal mining district in New Brunswick, Canada that was a focus area for the Geological Survey of Canada Targeted Geoscience Initiative Phase 3 project. As part of this project, more than 3500 gravimetric observations were acquired in the Bathurst Mining Camp, with an average spacing of 1-2 km, in 2006. The gravimetric data was reduced for an average crustal density value of 2.77 g/cm3 to obtain the Bouguer anomaly, which was analyzed and used to obtain 2.5D gravity models along five transects crossing the Bathurst Mining Camp. As a result of gravity modeling, a model of the general geometry of the main geological groups of the Bathurst Mining Camp (Fournier, California Lake, Tetagouche, and Miramichi) was obtained, which suggests that the Nine Mile Syncline is an open fold, and the Tetagouche Anticline is a gentle fold. Both folds are non-cylindrical and inclined, with their axial planes dipping in the 293° N direction: the angle of vergence of the folds increases towards the northeast of their axes. The structures under the Tetagouche Anticline axis gradually get deeper towards the Northeast reaching a maximum depth of 4 km. The depth of the structures modeled under the axis of the Nine Mile Syncline varies between 2 and 9 km, the deepest part being towards the center of the Bathurst Mining Camp; towards the northeast of its axis, the structures reach an intermediate depth of 4 km while towards the southwest they are 2 km deep on average.
Correrías por la arquitectura novohispana: los edificios, los materiales y los sistemas constructivos
Authors: González Leyva Alejandra
Published: December 2023

El texto destaca la importancia de Francisco de la Maza en la formación de estudiantes y maestros en historia del arte novohispano y de las obras que resultan de gran alcance en el aprendizaje, como las que tratan sobre arquitectura de los siglos XVI, XVII y XVIII. La autora de este estudio rastrea las correrías por las que ha pasado el estudio de la arquitectura novohispana, a partir del trabajo del historiador pionero, y propone que en la obra del pionero se encuentra el germen del gusto por los materiales, las técnicas edilicias e incluso por las etapas constructivas. González Leyva se une a la propuesta de De la Maza que proclama que “las esculturas y pinturas […] acompañan a la arquitectura como esclavas”, y concluye que no hay que olvidar la imagen como centro de la reflexión artística.
Construir desde la ausencia. Un acercamiento historiográfico a Francisco de la Maza en Las piras funerarias en la historia y en el arte de México
Authors: Baz Sánchez Sara Gabriela
Published: December 2023

En este texto busco reflexionar sobre las posibilidades simbólicas de la ausencia, a fin de plantear una indagación epistémica que permita valorar, desde una perspectiva distinta, las contribuciones de Francisco de la Maza, en particular, en Las piras funerarias en la historia y en el arte de México (1946). Parto de la base de que esta obra merece una revisión historiográfica más detenida y que, en justicia, su apreciación crecería muchísimo si se planteara un análisis al considerarla en el marco de la opera omnia de su autor. Lo que me propongo hacer a lo largo de estas páginas es mucho más limitado; consiste en construir un andamiaje mediante el cual se pueda abundar en la estructura con la que De la Maza propuso una serie de enunciaciones sobre el arte efímero y, con ello, sentó las bases para formular conocimiento.