bluuebunny/crossref_metadata_2025 huggingface dataset:
Current Concepts and Future Perspectives of Stem Cell Therapy in Peripheral Arterial Disease
Authors: Chukka Kereena
Published: January 2024

Some advanced stage peripheral arterial disease (PAD) patients will not eligible for revascularization strategies. From the last two decades stem cell therapy (SCT) has been explored as an alternative therapy for no option advanced stage PAD patients. Therapeutic motif of this novel therapy is to promote the collateral vessel formation that will improve the blood flow to ischemic leg that in turn can prevent major amputations. This mini review provides the brief outline of the use of autologous and allogeneic SCT for the treatment of advanced stage PAD
Osteometrical Study on Age Related Changes of the Skull of Yankasa Ram
Authors: SA Shehu
Published: January 2024

There is dearth of information on the biometry, clinical and applied anatomy of the head region, general morphology on the indigenous breed of sheep in particular, hence led to the motivation behind this study. This study gives the first biometric description of the skull of Yankasa indigenous breed of sheep in Nigeria. Twenty five heads (5[0-6months], 5[6months- 1year], 5[1-2years], 5[2-3years], 5[3years- above]) were collected from purposively and randomly sampled Yankasa male sheep from a slaughter slab and processed for Biometrical investigation. Several biometrical measurements were recorded from each of the 25 skulls. From these, simple descriptive statistical analysis was obtained. The values obtained from these groups were increasing with ages. This study has described the biometric characteristics of the Yankasa sheep and concludes that a contribution for comparative model for other African local ovine breeds in general and Nigerian ovine breeds in particular has being made. Being the first study of its kind in Nigeria, it makes a significant contribution to a better understanding of the Yankasa sheep skull. It is envisaged that the results obtained in this study will be useful as baseline data in anatomical and archaeological studies
Ultrasound Findings of Diffuse Liver Disease: Basic Steps to Understanding Sonographic Features
Authors: Seo Jun-young
Published: January 2024

The ultrasound examination, capable of non-invasively detecting subtle changes in the liver's structure and form, can be extremely helpful. It is not only useful in identifying liver tumors but also in diagnosing and differentiating various liver diseases. Continuous monitoring with ultrasound is especially valuable in patients with chronic hepatitis B and C, as well as other chronic liver diseases, for understanding disease progression and early detection of hepatocellular carcinoma. It is also used in determining the degree of liver fibrosis. Therefore, our goal is to enhance diagnostic capabilities by describing basic ultrasound findings related to diffuse liver diseases.
Critical Evaluation of Ayurvedic Shabda Pariksha (Auscultation) In Diagnosis of Diseases WSR to Computerized Sound Analysis
Authors: SD Waghe
Published: January 2024

The various sound produced in the body are used as tools in the diagnosis of disease by Ayurvedic acharyas. Acharya Charaka, in Vimansthana, had asked to examine the bowel sounds, joint crepitation and other peculiar sounds produced in the body such as cough and hiccups to diagnose the particular disease condition of particular system. Apart from this ancient Ayurvedic scholars have described the typical sound produced in various disease conditions such as Tamak shwasa (Bronchial Asthma) causing audible wheeze. Maha Shwasa (Kussmaul’s breathing) causing loud audible wheeze. Krukaj Kasa (Whooping cough) causing characteristic Whoop sound, Swarabheda (Laryngeal disease) causing hoarseness of voice. These qualitative acoustic differences of cough could be well picked up by the trained physicians. Attempts to record the cough sound digitally and to analyse it on computer software are being going on across the globe. Examination of waveforms and spectrograms related to coughing as obtained from computerized respiratory sound analysis should hold a future acoustic based laboratory diagnosis of cough. Furter Ayurveda is also of the view that every individual has characteristic voice depending upon the doshik predominance of his body constitution. It is observed and concluded that sound examination can be used as tool to diagnose the disease and body phenotype as mentioned in Ayurveda.
Scientific Application of Bhasma Pareeksha
Authors: K Veena
Published: January 2024

Even after Shodhana, the Rasadravya’s are not easily absorbable and assimilable because of their inorganic properties and non-homogeneity, so need to conversion of original metal / mineral into oxide or sulphide form to maintain of alkalinity and neutralizing the harmful acids. In Classics, Bhasma pareeksha are mentioned for the prepared bhasma before administration of the bhasma. These tests are considered as a basic quality control tests for Ayurvedic bhasmas. These tests are included many years ago but those tests having scientific base to assess particle size, lightness etc. By this it can be conclude with the modern parameters like Nano particle, chemical composition etc.
A Review of Vatika Shiroroga and its Ayurvedic Management
Authors: S Sakshi
Published: January 2024

The modern man must cope with the variety of difficulties such as stresses, and anxieties. One or more psychosomatic disorders have been linked to etiopathogenic mental elements such as excessive crying, anguish, fear, and terror. Regular and unnatural eating habits, repressing natural urges, less time of relaxation and a lack of proper sleep are inseparable components of our routine, that drain the body's energy and eventually result in disease. Most psychosomatic disorders are caused by a combination of these physical elements and persistently stressful psychological states. One such psycho-somatic is tension headache that is comparable to Vatika Shiroroga is mentioned in Ayurvedic texts. The Vataja-Shiroroga is a violent headache attack that has no apparent explanation, gets worse at night, and is eased by applying pressure, a bandage, or fomentation to the head. This attack is thought to be caused by the derranged Vayu. Its management requires thorough understanding of the condition, application of Nasya, Shirodhara, Dhumpaan, and correct aahaar-vihaar in addition to the ayurvedic medications that fall under the category of medhaya medications.
Pharmacognostic Evaluation of Shadanga Ghrita Herbs
Authors: N Laxmi
Published: January 2024

Efficacy of any formulation depends on their genuineness of herbs used. The present investigation was carried out to characterize the Ayurvedic preparation Shadanga Ghrita, a polyherbal formulation comprising of 6 ingredients, viz, Kutaj (Holarrhena antidysenterica Wall), Daruharidra (Berberis aristata DC), Pippali (Piper longum Linn), Shunthi (Zingiber Officinale Rosc), Katuka (Picrorhiza kurroa Royle ex Benth), Laksha (Laccifer lacca Kerr.) On the basis of the pharmacognostic parameters such as preliminary pharmacognostical study (color, odor, taste, appearance, texture and fracture), extractive values, ash values, moisture contents, foreign organic matter, microscopy (histology and powder microscopy) to confirm their identity, quality and purity, pharmacognosy study was carried out. To the best of my knowledge, there is no published report on the scientific analysis of Shadanga Ghrita till date, hence the present work was evaluated to develop the quality control parameters of Shadanga Ghrita ingredients to confirm their purity and identity.
In-vitro Evaluation of Anti-Urolithiatic Activity of Cuminum Cyminum Seed Extract on Calcium Oxalate Stone
Authors: V Paheerathan
Published: January 2024

The present study was undertaken to evaluate the Invitro Anti- urolithiatic activity of the selected plant Cuminum cyminum seed extract by using the titrimetry method. The work was performed by using invitro Anti- urolithiatic model for calculating percentage dissolution of Calcium oxalate stone. The standard drug was cystone. The seed extract of Cuminum cyminum showed the higher dissolution than the standard drug cystone. The 30mg/ml seed extract of Cuminum cyminum was highest among the test groups. This study has been primary evidence for Cuminum cyminum as the plant which possess Antiurolithiatic property.
Management of Cervical Spondylosis with Agnikarma Therapy: Case Study Article
Authors: B Beena
Published: January 2024

The clinical disease known as sandhigata vata causes structural and functional disarrangement in the joints with symptoms of sandhishoola, sandhishotha, akunchana prasarana, pravrittiscavedana, and in the later stages, hanusandhigatah, sandhigata vata can be identified as a joint disease. In the context of ayurveda, some clinical conditions, such as manyastambha, manyagraha, grivastambha, and viswachi, mimic cervical spondylosis however there are no degenerative changes in these illnesses. The only condition that can be highly appropriate with cervical spondylosis is sandhigata vata. Age-related wear and tear affecting the cervical vertebrae in the neck is known as cervical spondylosis. As the disc-dehydrate and shrink, sign of osteoarthritis develops, including bony spur. agnikarma having vata kapha shamaka properties like ushna, sukshma, and ashukari guna may be helpful relives pain and muscle spasm instantly so it can be used to treat cervical spondylosis.
A Case Study on Management of Asthigata Vata W.S.R. AVN of Femoral Head
Authors: M Kalatippi
Published: January 2024

Avascular necrosis of femoral head is a growing condition in the musculoskeletal clinic. This is mainly osteonecrosis caused by injury or occlusion in the blood vessels that supply bone tissue. AVN of femoral head is the most common type of necrosis because the artery that supplies this area is so narrow that it is easily injured, which then causes a lack of nutrition leading to necrosis. Modern medicine has no specific cures other than surgery. Moreover, it is expensive and unpredictable. In Ayurveda, Vata, Pitta, Rakta Dosha, Asthi, and Majja Kshaya play a major role in the pathogenesis of AVN. This article is aimed to nourish, repair, and regenerate Asthi Dhatu & Vatashamana. The current study, at the age of 28, diagnosed AVN of the femoral head was treated with Udvartana, Kshara Basti, Ksheera Basti, and Shasthika Shali Pinda Sveda which plays a significant effect in the improvement of pathology.
Role of Vajigandhadi Taila Matra Basti in Gridhrasi (Sciatica)
Authors: C Neetika
Published: January 2024

It is one of the most common musculoskeletal complaints encountered in clinical practice. Its prevalence has been estimated to be 1-5% in India. A large study reported an incidence of 28.0 episodes per 1000 persons per year and for low back pain with sciatica an incidence of 11.6 per 1000 persons per year. Sciatica affects men a little more than women and is most frequent in the working population, with the highest incidence seen in those aged 20-64 years. Due to busy professional working like improper sitting, over exertion, jerking movements during travelling, sports, increasing computerization trend, increasing body weight and mental stress create undue pressure on spinal structures which play an important role in causing sciatica. Being an alarming problem, it needs an effective and safe treatment. From the time immemorial, innumerable analgesics have been added to the arsenal of the modern physician only to reveal its futility. Though, modern therapeutics has a broad spectrum of the drug for management of this disease, aftermath of which is that they are having serious side effects. SCIATICA being a challenging lifestyle condition needs proper management. Modern medicine is not having no specific management sciatica that’s why an elaborate study has been undertaken to have an in depth knowledge about the concept of sciatica in Ayurveda terms.
Epidemiology of Inequity from a Syndemic Perspective: A Long Way to Go
Authors: Stangl Jorge Mandl
Published: January 2024

Epidemiology “is a tool for changing the world, not just for studying the world”. Bill Foege
Consciousness Energy Healing Treatment and Its Impact on the Structural Properties and Isotopic Abundance Ratios of Thiamine
Authors: S Jana
Published: January 2024

Thiamine (vitamin B1 ) is an essential water soluble vitamin required in all living cells for many cellular functions. The objective of the study was to investigate the impact of the Trivedi Effect® -Consciousness Energy Healing Treatment on the isotopic abundance ratios (PM+1/PM and PM+2/PM) and structural properties of thiamine hydrochloride using LC-MS, GC-MS, and NMR spectroscopy. Thiamine sample was divided into two parts, one part of the sample was termed as untreated/control thiamine, while the other part of the sample received the Trivedi Effect® -Biofield Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Mr. Mahendra Kumar Trivedi and designated as Biofield Energy Treated thiamine. The LC-ESI-MS analysis of both the thiamine samples showed the mass of parent molecular ion at m/z 265.03 (calcd for C12H17N4 OS+ , 265.11) at the retention times (Rt ) 1.51 minutes with similar fragmentation pattern. But, the relative peak intensities of the treated sample were significantly improved compared to the control sample. The isotopic abundance ratios of PM+1/PM (2 H/1 H or 13C/12C or 15N/14N or 17O/16O or 33S/32S) and PM+2/PM (18O/16O or 34S/32S) were significantly increased by 43.60% and 42.68%, respectively in the treated thiamine compared to the control sample. Therefore, 2 H, 13C, 15N, 17O, and 33S contributions from C12H17N4 OS+ to the isotopic m/z 266 and 18O and 34S contributions to the isotopic m/z 267 was significantly increased in the treated sample compared with the control sample. The GC-MS mass peak intensity of the treated sample (52940.7) was significantly increased by 131.01% compared to the control sample (22917.04). The proton and carbon signals for CH3 , CH2 , NH2 , CH, =C=, and C-OH groups in the 1 H and 13C NMR spectra of the control and treated samples were similar. The increased mass peak intensities and isotopic abundance ratios in thiamine might be due to the Trivedi Effect® -Consciousness Energy Healing Treatment via the possible mediation of neutrinos, which may change the intra-atomic bond strength, its physical stability, kinetic isotope effects of the treated thiamine. Thus, the Trivedi Effect® -Consciousness Energy Healing Treated thiamine would be advantageous for designing better nutraceuticals and pharmaceutical formulations which might provide better therapeutic response against vitamin B1 deficiency and related disorders, including beriberi, Korsakoff’s syndrome, Parkinson’s and Alzheimer’s diseases, maple syrup urine disease, Leigh’s disease, optic neuropathy, alcoholism, and aging.
GC-MS Analysis of Phytochemical Composition, Antibacterial and Antioxidant Properties of Ethanolic Extract of Detarium microcarpum (OFOR)
Authors: Stanley C Ihenetu
Published: January 2024

The increasing use of Detarium microcarpum as food and in treatment of different ailment and the understudy of its bioactive and chemical composition resulted to this work on GCMS studies of phytochemical composition, antibiotic and antioxidant properties of ethanolic extract of ofor (Detarium microcarpum). Ethanol extract of seed of Detarium microcarpum showed the presence of the various phytochemicals; saponin, flavonoids, steroid, proteins, anthraquinnones and alkaloids. The following phytochemicals were absence from the sample; tannins, terpenoids, cardiac glycoside, phulobactanins, phenolic compounds and reducing sugars. GCMS analysis showed the presence of 9, 12-Octadecadienoic acid (Z,Z)- as a main compound in the extraction. The aqueous extraction showed 28.59% and the least compound showed methyl tetradecanoate and the aqueous extraction is 1.13%. The activities of 10mg/2ml of the seed extract on selected bacterial organisms with Minimium Inhibition Concentration (MIC) of Eseterichia coli (10μl), Pseudomonas aeruginosa (100μl) Staphylococcus aureus (50μl) and Bacillus suptili (20μl) justified the use of the plant seeds for various treatments by local traditional practitioners. Antioxidant activities of Detarium microcarpum seed determined by the free radical scavenging activity (DPPH) assay method indicated a steady increase in the scavenging activity of free radicals in all extracts from 322 to 1011μg/mL. The usage of this ornamental plant should be promoted as an alternative for synthetic chemicals as it is easily available, grown and maintained, accessible and affordable. The high antioxidant potential, free radical scavenging activity and anti-oxidative enzymes of Detarium microcarpum should be utilized to develop new drug candidates for antioxidant therapy
Exploring the Chemical Diversity of Andrographis paniculata: GCMS Characterization of Ethyl Acetate Extracts
Authors: EE Etim
Published: January 2024

This research delves into the diverse phytochemical composition of Andrographis paniculata, a renowned medicinal herb with a rich history in traditional use. Employing GC-MS, our objective is to comprehensively identify and characterize phytochemical compounds within ethyl acetate extracts. The study holds significant promise due to the broad spectrum of medicinal applications associated with Andrographis paniculata. The ethyl acetate extracts of the plant were obtained using the cold maceration method, followed by preliminary phytochemical analysis. The findings reveal the presence of steroids, terpenoids, and alkaloids in the ethyl acetate extracts, while tannins, saponins, flavonoids, and cardiac glycosides were notably absent. GC-MS analysis further unveils 29 unique compounds, encompassing alkaloids, terpenoids, and wax. Benzeneethanamine, 2, 5-difluoro-β, 3, 4-trihydroxy-N-methyl, an alkaloid, and 3, 7, 11, 15-tetramethyl-2-hexadecen-1-ol, a prominent terpenoid, stand out among the identified compounds. This research addresses a dearth of phytochemical analysis within the specific locale of Kom-Kom in Oyigbo L.G.A of Rivers, making it a unique contribution to the field. The variations in phytochemical composition attributed to geographic location and extraction solvents underscore the importance of this study
Green Synthesis of TiO2 Nanoparticles Using Root Extract of Asparagus racemosus (Shatavari) and Evaluation of its Antibacterial, Antioxidant and Antidiabetic activities
Authors: A Singh
Published: January 2024

Since ancient times, Asparagus racemosus, a traditional herb with various health advantages, has been used to cure a wide range of illnesses. Researchers sparked a lot of interest in the biological methods for producing nanoparticles (NPs). This study’s objective was to synthesize titanium dioxide nanoparticles (TiO2 NPs) utilizing the top-down nanofabrication method. Asparagus racemosus root extract was used to produce titanium nanoparticles utilizing green chemistry. The nanoparticles were characterized using UV-Visible spectroscopy, SEM (Scanning Electron Microscope), and EDX. According to the SEM images the particles are spherical in shape with an average size of 89.59 nm. The antibacterial activity was done with 3 bacterial strains i.e., E. coli, Pseudomonas aeruginosa and Bacillus subtills. Antioxidant activity was evaluated by DPPH and phosphomolybdate assays, the calculated IC50 was 85.18±0.55 µg/ml and 66.4±1.3 µg/ml respectively. The calculated IC50 value for alpha amylase assay was 46.59±2.81 µg/ml. As per the outcomes it is concluded that the plant mediated titanium nanoparticle is very potent which can be used in pharmaceutical and biomedical areas.
Redshift Estimation of SDSS Photometric Data Based on AutoGluon-Mix
Authors: Bo Qiu
Published: January 2024

Redshift is an important parameter of galaxies, and the use of photometry data for redshift estimation has always been a focus in the field of astronomy. This study explores a redshift estimation method for SDSS photometric data based on the AutoGluonMix algorithm, in which the integrated learning methods, including K-nearest neighbors, random forests, XGBoosted trees, LightGBM boosted trees, CatBoost boosted trees, Extremely Randomized Trees, and neural networks, improve the accuracy of redshift estimation through comprehensive strategies. The experimental results show that AutoGluon-Mix performs extremely well compared to other algorithms for both early and late type galaxies.
Micromorphology and Histochemistry of Vegetative Organs from Nicandra Physalodes (L.) Gaertn (Solanaceae)
Authors: Agra Maria de Fátima
Published: January 2024

Nicandra physalodes (L.) Gaertn is a sub-shrub used in folk medicine for various purposes, as it is also considered a toxic plant. Due to its ethnobotanical importance, a study of vegetative organs (leaves, stem, root) of this species was carried out, for its micromorphological and histochemical characterization, with the objective of finding parameters to support the taxonomy and quality control of their ethnodrugs. Paradermic and cross sections were carried out on fresh samples of leaves, stem and root, from the plant collected in the municipality of Bananeiras, State of Paraíba, Brazil, as well as histochemical tests with specific conductors, following the usual techniques in botanical anatomy. It was observed that N. physalodes has an amphistomatic leaf blade, anisocytic and anomocytic stomata, 1-serial epidermis, sinuous anticlinical cell walls, dorsiventral mesophyll, 1-serial palisade parenchyma and the 3-4-serial spongy border; biconvex midrib, bicolateral, arched; semicircular petiole with lateral, adaxial projections, 5-6-seriate collenchyma and vascular system similar to the midrib, 2 central bundles and 2 accessories in the lateral projections. The stem is irregularly pentagonal, epidermis 1-seriate, angular collenchyma 3-4-seriate, prismatic crystals are observed in the cortex and medullary parenchyma, and the vascular system is amphiphilic siphonostelic. The root is circular, with the endoderm 1-serial, siphonostelic vascular system. Histochemical tests showed a positive reaction for lipids, lignin, starch, alkaloids, phenolic compounds and proteins in the rib, petiole and stem. The anatomical character set of the leaf epidermis, stem and root together with the histochemical data are distinctive for N. physalodes, who support her taxonomy and the quality control of her ethnodrugs.
Opinion on Botany and Plant Pathology
Authors: Gorrer Daniel
Published: January 2024

The Open Access Journal of Botanical Insights has begun its journey. It is a journal that has peer review, based on the highest scientific rigor, and that publishes articles in various fields of modern botany. However, it is not only open to original articles, it also seeks to incorporate review articles, short communications, opinion articles, editorials and obituaries among others. Through these, we hope that readers will find in this journal a wide range of articles that will enrich their knowledge.
Cancer Prevention versus Cure: What is our Best Option?
Authors:   Medwin, Petrak Karel
Published: January 2024

Huge resources are being expended in search of cancer therapies, with a limited success. Cancer is believed to originate from an irreversible genetic alteration which is a part of both normal and abnormal biological processes. It is questionable whether such essential biological behavior can be put under our sufficient control to cure cancer. Given that events leading to cancer development appear to be too complex to be successfully manipulated by drug therapies, initiatives to “cure cancer” should be reevaluated and reconsidered, with a likely anticipated conclusion that taking steps to limit cancer initiation might be more cost-effective, and hence focus research efforts on measures to prevent rather than cure cancer
Combating Immunosuppression within Tumor Microenvironment: A Novel Approach for Drug Design
Authors: Mirlekar Bhalchandra
Published: January 2024

Recent efforts for cancer treatment include chemotherapy, radiation therapy, surgery, molecular targeted therapy and immunotherapy. Most of these therapies can be beneficial in patients with early stage disease, but this therapy is ineffective to treat advanced stage of metastatic cancer. During cancer initiation and metastasis innate or acquired immune suppression are among the reason for reduced responsiveness to therapy. Majority of the studies of decreased responsiveness focus on marked “immune-suppression” within tumor microenvironment. Several studies have emphasized the impact of therapy-induced physiological changes in cancer cell that can inhibit anti-tumor effect by promoting immunosuppression. These undesired host effects can enhance tumor growth and even malignancy. These effects fall out as a result of systemic release of various regulatory cytokines, chemokines and host immune regulatory cells, which can infiltrate into the tumor. In short, the preferred therapy to target tumor can be offset by reactive effector immune response; by preventing or combating the immunosuppression represents a potentially new approach to boost the effectiveness of systemic and local cancer therapies.
A Molecular Approach to the Diagnosis, Prognosis, and Treatment of BCR-ABL1-Positive Chronic Myeloid Leukaemia
Authors: M Nandagopal
Published: January 2024

BCR-ABL1 is a gene sequence expressed in an abnormal copy of chromosome 22 in people who are diagnosed with certain forms of leukaemia. Molecular monitoring with BCR-ABL real-time quantitative Polymerase chain reaction (RQ-PCR) for assessing treatment success and quantifying minimal residual disease (MRD) is a crucial determinant of practical therapeutic decisionmaking in chronic disease management. Chronic myelogenous leukaemia (CML) and several other leukaemia’s, unlike other malignancies, are caused by a single, particular genetic mutation in one chromosome. This review article assesses CML, TKI response in targeted CML therapy, and data interpretation in molecular diagnosis. It highlights the purpose, application, and likely future of PCR-based molecular surveillance.
Interpersonal Communication Message Types: Ranking of Importance by Kinesiology Undergraduates
Authors: Lattimore Diana
Published: January 2024

Effective practitioner-patient communication is important for the physical and psychological aspects of sport injury and recovery. Research indicates that patients desire better communication with health care providers. Although interpersonal communication message types play an essential part in provider-patient interaction, undergraduate kinesiology students are not privy to the literature or trained in the design of the messages inherent and essential to their future professions (e.g., physical therapy & athletic training). The purpose of this study was to assess the perceived importance of interpersonal message types for health care providers in a sample of undergraduate kinesiology students (n=153). Participants rankedordered nine foundational interpersonal message types, and message rankings were fairly consistent across participant year and sex. Results indicate that instructions and explaining illness dominated the rankings.
The Need for a Dynamic Systems Approach in Kinesiology Research
Authors: Kinnunen David
Published: January 2024

Objective: This submission addresses the need for the use of Dynamic Systems Theory (DST) in Kinesiology research across the sub-disciplines. Materials and Methods: Theoretical discussion Results: there is a need for a shift in Kinesiology research paradigms.
The Impact of Labour Induction at 38-39 Weeks Period of Gestation versus Expectant Management in Low Risk Pregnancies
Authors: Pitty Nikita
Published: January 2024

Background: The recommendations for induction of labour have been restricted to postdated pregnancies, though many studies have assessed the safety of elective induction at term. The aim of the current study was to assess the outcomes of elective induction of labour at 38-39 weeks period of gestation among low risk pregnancies. Methodology: This was a hospital based observational study, on 134 subjects assessed for fetal well-being and induced based on Bishop’s score. The labour and perinatal outcomes were compared between pregnant women subjected to elective induction of labour & expectant group. Results: Of the 67 subject in the electively induced group, 28.4% delivered by a caesarean section in comparison to 31.3% of the 67 subjects in the expectant group (p-0.143). The mode of delivery in either of the groups was independent of the method of induction & parity. The mean induction to delivery time, maternal outcomes and duration of hospital stay was similar in the 2 groups. Fetal outcomes analyzed by NICU admissions was similar in the 2 groups (p-0.635), though the admissions were significantly more in the electively induced group who underwent caesarean section (p-0.001). Conclusion: Induction of Labour at 38-39 weeks in low-risk women did not result in increase in caesarean section or composite adverse perinatal outcomes. Our data may help low-risk women and their clinicians make decisions regarding benefits of induction of labour at term in an institutional setting.
The Role of Marriage Brokers on Adolescent Girls’ Early Marriage: Qualitative Evidence-The Case of West Hararghe, Ethiopia
Authors: Tesfa Anene
Published: January 2024

Marriages below the age of 18 are either forced or by own interest, influenced by different factors. The objective of this paper is to describe the role of marriage brokers in adolescent girls’ marriage in West Hararghe, Oromia region, Eastern Ethiopia. Qualitative data were drawn from a formative baseline (March to August 2016) and consecutive studies including the mid-term (May 2018 to August 2018) studies of Abdiboru, a Girls’ SRH and empowerment project. As findings demonstrate, adolescent girls below the legal age of marriage are forced to accept marriage proposals convinced by intermediaries/marriage brokers. Marriage brokers can be peers, relatives, elders or any skillful people in convincing and persuading girls. Marriage brokerage is commercialized and as a result, girls go through the burdens of early marriage and early child bearing. Marriage brokerage is a common act in the study area resulting in brokers to have a significant role on adolescent girls’ marriage. They play an inevitable role in arranging potential matches for adolescent girls. Programmers working on ending child marriage and related areas need to include these influential people in designing interventions.
A Case of Postnatally Diagnosed Sirenomelia in a Patient with Poorly Controlled Type 2 Diabetes Mellitus
Authors: Maher James
Published: January 2024

Sirenomelia, also known as mermaid syndrome, is a rare constellation of anomalies of caudal fetal development associated with fusion or complete absence of the lower limbs. The prognosis for neonatal survival is poor. Diagnosing this condition can pose a challenge due to associated oligo/anhydramnios. First-trimester transvaginal and transabdominal anatomy ultrasound performed between 11-13.6 weeks of gestational age (WGA) can evaluate fetal anatomy for anomalies. Transvaginal (TVUS) ultrasound offers the best opportunity to detect this condition. We present a case of a 1240g baby born from a 34yo with poorly controlled type 2 diabetes (T2DM) delivered via repeat cesarean section. Antenatal management for presumed previable pre-labor rupture of membranes (PROM) was provided. Postnatally, the infant had unexpected defects consistent with Sirenomelia. The neonatal exam showed webbed legs due to fused knees and toes, microcephaly, two-vessel umbilical cord, ambiguous genitalia, and bilateral renal agenesis. After confirming bilateral renal agenesis, we provided palliative care. The neonate died 12 hours after birth from cardiac arrest.
Recurrent Miscarriage
Authors: Haider Rehan
Published: January 2024

Recurrent failure, the heartbreaking knowledge of couples who find it difficult to start or extend their families, is a baffling and excitedly distressing generative strength issue. Defined as the incidence of three or more successive pregnancy misfortunes before the 20th temporal length of the event or entity’s existence of a process of early development, recurrent failure influences about 1-2% of couples in general. This abstract delves into the causes, diagnostic approaches, and administrative policies for repeating miscarriages. The study of repeated failure in animals is multifactorial, encompassing hereditary, fundamental, endocrine, immunologic, and tangible factors. Key demonstrative forms include karyotyping, Hysterosalpingography, and hormonal evaluation. Management designs depend on the fundamental causes and accompanying interference’s, ranging from behavioral modifications and pharmacological situations to surgical interference’s. Psychological support is an essential component of caring for the sentimental toll that repeated failure takes on couples. Recent advances in research have cleared potential attacks to a degree of preconception through historical experiments and immunomodulatory remedies. Furthermore, continuous studies are examining the role of behavioral determinants, including diet and stress, in repeated failures.
Balinese Shadow Puppet Characters Detection In The Wayang Peteng Performance Using The Yolov5 Algorithm
Authors: I Gusti Ngurah Bagus Putra Asmara  , Made Windu Antara Kesiman  , Gede Indrawan
Published: January 2024

To generate greater public interest in Balinese shadow puppet performances, it is crucial to explore novel ways of educating viewers about the characters showcased in the plays, as many individuals may need to become more familiar with them. In Object Detection, an algorithm is called You Only Look Once (YOLO). This research utilizes the YOLOv5 algorithm to detect Balinese shadow puppet characters in the "wayang peteng" performances. The dataset consists of 5040 images, divided into training, validation, and test data, with a ratio of 7:2:1 (This ratio helps in effectively training and evaluating the YOLOv5 model on a diverse set of data). Four YOLO models are trained, each with a different number of epochs (a single iteration of training when the entire dataset has been passed forward and backward through the neural network), resulting in 12 models. All models are tested using the test data images to obtain precision, recall, and mean Average Precision (mAP) metrics. Additionally, three videos measure the average frames processed per second. The research findings reveal that the YOLOv5n model with 200 epochs achieves the best results, with a precision value of 1, recall of 1, mAP@0.5 of 0.995, mAP@0.5-0.95 of 0.985, and 128.20 frames per second.
Usability Testing on The Mobile Gras (Green Trash System) Application Using The Usability Scale System Method
Authors: Desnanjaya I Gusti Made Ngurah , Sandika I Kadek Budi , Sarasvananda Ida Bagus Gede , Aditama Putu Wirayudi , Wiguna I Komang Arya Ganda
Published: January 2024

This study focuses on the GRAS (Green Trash System) mobile application, developed under the KEDAIREKA program to enhance waste management efficiency. The application is an integral part of the GRAS smart waste system, designed to facilitate real-time monitoring and reporting of waste capacity issues. The primary objective is to streamline waste sorting processes and educate users, particularly students, about sustainable waste management practices. The system features innovative sensor technology that provides audio feedback for correctly sorted waste, thus reinforcing correct behaviors. To assess the application's effectiveness, we conducted a usability test using the System Usability Scale (SUS) method. Data were collected through questionnaires to evaluate the application's ease of use, efficiency, and user satisfaction. The results indicated a high level of usability, with most users experiencing seamless interaction with the application, affirming its potential as a tool for effective waste management education and practice.
Scrutinizing the Awareness of Hidden Curriculum: Connecting Lecturers to Themselves, Students, and Non-Engineering Study Programs
Authors: Ardiansyah Welly , Risnawati  , Zakaria  , Asyari Lutfi , - Abdurrahmansyah
Published: January 2024

The hidden curriculum plays a crucial role in the entire teaching process, and there is no doubt about that. It possesses the irreplaceable value and function of explicit curriculum. Therefore, teaching at a college should pay attention to utilizing hidden curriculum. On the basis of fully understanding the characteristics and functions of the hidden curriculum, this study analyze the understanding of the hidden curriculum, interviewed selected lecturers to probe deeper regarding how they use the hidden curriculum and made observations notes on classroom environments and interactions. A mixed-method approach is used in this study. Purposive sampling was used to select 100 non-engineering lecturers in State Polytechnic of Sriwijaya for the statistical society. To collect information, survey, interview, and observation were applied. The findings showed that the majority of lecturers had knowledge of the hidden curriculum and utilized it to improve their classroom through body language, tone of voice, physical classroom changes, setting and maintaining expectations and norms, and reflecting upon their teaching. It was also found that all departments brought their mission statements and ethos to life.. A further contribution of the study is to provide a deeper understanding of the hidden curriculum enacted in private higher education, as well as what lecturers experience the hidden curriculum to be like. A better understanding of hidden curriculum is necessary to improve its use in higher education.
Senior High School Mathematics E-Module Based on STEM Orienting to Higher Order Thinking Skills Questions
Authors: Sukendra I Komang , Widana I Wayan , Juwana I Dewa Putu
Published: January 2024

At present schools have find difficulty providing teaching materials to support textbooks. Therefore, it is necessary to develop teaching materials in the form of e-modules. The research aimed to develop senior high school mathematics e-module high-quality based on STEM orienting to HOTS questions.. The research used the development of Plomp model. The phase of the model involved; the beginning investigation phase, design phase, realization/construction phase, test phase, evaluation, revision, and implementation phases. The validity of e-module was valued by three material experts an three media experts by using evaluation sheets and examining with Gregory cross tabulation. Data obtained through limited field tests, wide field tests 1 and wide field tests 2 to improve the results of the e-module product through suggestions and input on the prepared pond. The result of evaluation showed can be concluded that senior high school mathematics e-module based on STEM orienting to HOTS which was developed filled the aspects of validity, practicality, and effectiveness. It could be used in the learning process. The implications of the HOTS-based on STEM-orienting to high school mathematics E-module is very helpful for students to learn at anywhere and anytime independently.
Merdeka Belajar: Solution for Developing Creativity and Independence in Early Childhood in the Era of the Industrial Revolution 4.0
Authors: Munastiwi Erni
Published: January 2024

Entering the era of the industrial revolution 4.0, the world has experienced many changes, especially the world of education. The data shows that creativity and independence are in the spotlight in the era of the industrial revolution 4.0, with high creativity and independence, children are able to compete and be able to answer national challenges. This research was conducted in order to analyze the independent learning correlation which is the solution of Developing Creativity and Independence of Early Childhood in the Industrial Revolution Era 4.0. The type of research used is quantitative research which is research based on the philosophy of positivism. The population in this study is educational institutions in one area, while the sample of this study is 3 schools. Samples were taken in Kindergarten B class and 10 children were taken from each school. Data collection in this study is use checklist questionnaire. Researchers tested the validity of the data using the validity test and reliability test. The result found Pearson correlation value between Pearson Creativity and Independence is 0.684 which is classified as having a strong relationship and the Sig value. (2-tailed) of 0.000 is smaller than 0.05. Based on these results, it can be seen that there is a significant relationship between independent learning and creativity with children's independence, with good creativity and independence. Children have readiness to face the challenges of an increasingly developing technological era.
Basics Fashion Photo Editing Module for Fashion Design Students Based on Indonesian National Work Competency Standards
Authors: Nugroho Julian Prio Dwi , Jerusalem Mohammad Adam
Published: January 2024

The limitations of the learning media on fashion photo editing materials become the main obstacle to achieving basic digital photo editing competence in the Fashion Photography course. Therefore, it is necessary to develop relevant modules. This study aims to develop an SKKNI-based basics fashion photo editing module for fashion students that can be used in the learning activities of fashion photography. This study is a research and development conducted using the ADDIE model. The subjects of this study were 30 students of the Fashion Design Study Program. The data were obtained from product evaluation by material experts and media experts as well as field trials involving research subjects. These data were analyzed using descriptive quantitative techniques. The result of this study is a basic module for fashion photo editing based on the basic digital photo processing competency sub-unit materials in the Indonesian National Work Competency Standards of Photography. From the material aspect, the developed module was considered valid (0.85) and reliable (0.742). The media aspect of the module was also regarded as valid (0.82) and reliable (0.714). Thus, it can be concluded that the module developed was of expert quality and feasible to use. Based on the percentage of students achieving the minimum passing grade, the developed module is categorized as effective (80%) as a learning media in the basic materials of fashion photo editing.
Quantile Regression Analysis for Students’ Difficulty Level in Learning Statistics Online
Authors: Casinillo Leomarich F
Published: January 2024

Statistics learning in the time of distance education makes students uneasy due to the difficulties in the learning environment and processes. This article aims to analyze the level of difficulty faced by students in statistics distance education and captures the causal factors affecting it. Cross-sectional secondary data were used from a current study in literature and described by standard statistical measures. The study utilized the level of difficulty in learning statistics during online setup as the dependent variable in the form of a scale of 1 to 10. The study used standard descriptive measures. Moreover, this study also use quantile regression models were constructed. Results depicted that students were facing "difficulty" as they learn statistics during distance education. The quantile regression revealed that the learning environment, inaccessible places (rural areas), and more family members are the statistically significant factors that influence the difficulty level in learning statistics online. This implies that due to the distractive place of learning, students cannot focus and penetrate their lessons. In addition, students were struggling with communication technology and internet access wherein it is vital in classroom engagement and the acquisition of learning resources. Hence, the study suggests that students must be supported by the government in regard to their learning needs and teachers must promote a positive and interesting educational environment. Furthermore, teachers must undergo training and workshops on how to be equipped in teaching statistics online.
Embarking on an Action Plan: Proposing Vark Test as the Need Analysis for Classroom Teaching and Learning
Authors: Tamat Norhamizah , Kamaruzaman Noorulziwaty , Ghazali Ezatul Marini Mohd
Published: January 2024

Learning styles represent the different ways in which individuals prefer to learn and engage with educational content. Learning styles are based on the idea that people have unique cognitive strengths and preferences that can influence their learning experiences and outcomes. By understanding their learning styles, educators can tailor their instruction to meet students' individual needs. This personalized approach helps engage students more effectively and enhances their learning experience. Students are more likely to be engaged and motivated when taught in a manner that aligns with their preferred learning styles. This leads to increased participation, active involvement in the learning process, and improved retention of information. The objective of this research is to propose a VARK questionnaire as the basis for the need analysis in planning the action plan in the action research. This research employed the action research design using the Kemmis and Taggart model, is a widely recognized framework for conducting action research. The respondents selected for this research were 30 students of the Diploma in Quantity Survey of Politeknik Sultan Azlan Shah. The respondents consist of 15 female students and 15 male students. it was found that respondents have different learning styles according to their preferences which are categorized according to VARK learning styles.
Implementasi Naïve Bayes Pada Data Mining Untuk Mengklasifikasikan Penjualan Barang Terlaris Pada Perusahaan Ritel
Authors: Wardani Ni Wayan , Nugraha Putu Gede Surya Cipta , Mahendra Gede Surya
Published: January 2024

Perusahaan ritel UD. Mawar Sari memiliki hingga 1,000,541 record data transaksi penjualan pada tahun 2019–2020 yang selama ini belum dipergunakan dengan baik. Data tersebut membutuhkan banyak ruang penyimpanan. Data tersebut juga belum dipergunakan secara efektif untuk tujuan apapun. Berdasarkan permasalahan tersebut, maka penelitian ini bertujuan untuk melakukan klasifikasi terhadap data transaksi penjualan untuk menemukan klasifikasi barang terlaris dengan data mining. Penelitian ini merupakan penelitian studi kasus yang menggunakan pendekatan penelitian kuantitatif. Metode yang digunakan adalah Naïve Bayes. Implementasi  penelitian ini menggunakan Rapidminer 9.0. Hasil penelitian dari klasifikasi data transaksi penjualan adalah klasifikasi produk yang laris dan tidak laris. Peneliti melakukan pengujian dengan 6043 data training dan hasil dari split validation terbaik pada split validation 0,7 dengan accuracy sebesar 93,82%. Hasil penelitian ini dapat digunakan dan berimplikasi baik untuk manajemen UD. Mawar Sari dalam pengambilan keputusan untuk menentukan suatu produk setelah mendapatkan hasil perhitungan data mining menggunakan metode Naïve Bayes.
The Relationship of the Quintuple Helix in Strengthening the Pancasila Character in the Millennial Generation for the Indonesian Nation
Authors: Lailatul Fitria Nurul Jannah
Published: January 2024

Indonesian worldview incorporates Godhead, humanity, unity, democracy, and social justice from communal life. Youth are alienated from Pancasila. They prefer modern, creative, and innovative social values. Exploring this to reinforce Pancasila ideals for youth is important. This study examines five interconnected helixes to reinforce Pancasila. The five helixes are education, economy, society, politics, and environment. This research used descriptive qualitative methods. Research data came from a literature review. Results suggest that the Quintuple Helix strengthens Pancasila for millennials. The quintuple helix interaction in Indonesia describes how academics, government, economic actors, society, and the natural environment promote innovation. Technically, not all helixes produce innovation because their roles and portions vary.