bluuebunny/crossref_metadata_2025 huggingface dataset:
PREDICTIVE MODELING OF N-ACETYL TRANSFERASE 2 SINGLE NUCLEOTIDE POLYMORPHISMS AND BREAST CANCER RISK USING IN-SILCO APPROACHES
Authors: Bilal Asif , Ahmad Sibtain , Tanvir Fouzia , Tariq Muhammad , Ramzan Kainat , Saleem Muhammad , Saleem Hafiz Ghulam Murtaza
Published: April 2024

N-acetyltransferase 2, also known as arylamine N-acetyltransferase, commonly known as NAT2. The objective of this study was to identify non-synonymous SNPs of NAT2 and their association with breast cancer using computational analysis. For this purpose, different online tools like SIFT, Polyphen, Polyphen-2, fuNTRp, SNAP2 (to identify pathogenic SNPs), SNP&GO, PhD-SNP, PredictSNP, MAPP, SNAP, MetaSNP, PANTHER (disease associated SNPs), Mu-Pro, I-Mutant, and CONSURF (to check protein stability) were used. Post-translational modifications (PTMs) were detected by Musitedeep, Protein secondary structure by SOPMA, and protein to protein interaction by STRING. Nineteen SNPs having rsIDs (rs1435840670, rs747536177, rs753310036, rs1175197943, rs1805158,rs1019316375, rs201345576, rs1476310549, rs72466458, rs201080763, rs746734312, rs561124342, rs549917500, rs1383708687, rs4986996, rs559660817, rs1344597702, rs749948990, and rs148566670) showing mutations on Y6H, G11V, F37S, H43P, R64W, G65D, W67R, W67C, C68Y, N72S, G83S, G83A, H107Q, V112M, D122N, D122G, C223W, G230V, and L275M, respectively found to be completely deleterious. The PTMs found were Glycosylation at amino acid number 125; Ubiquitination at 256 and 282, Acetylation at 272; Hydroxylation at 281, and Phosphorylation at 287. The protein secondary structure consisted of Alpha helix (Hh) 80 is (27.59%), Extended strand (Ee) 65 is (22.41%), Beta turn (Tt) 21 is 7.24% and Random coil (Cc) 124 is (42.76%). Protein-protein interaction analysis revealed that it has strong interaction with Myeloperoxidase, Xanthine dehydrogenase, Liver carboxylesterase 1, Glutathione S-transferase Mu 1, and with cytochrome family. Based on these results, it is concluded that these SNPs found in NAT2 are involved in breast cancer. Further in vitro and in vivo analysis should be performed to conduct these interactions.
Growth, Opportunities and Challenges of E Learning Model in Higher Education and Professional Certification
Authors: Aishwarya Suraj Ray Dr. Poonam Nikam,
Published: April 2024

The currently available database on scholastic pursuits is both outdated and inadequate. Incomplete coverage, excessive gaps, etc., plague the gathering and sharing of educational data. More and more schools and students are taking advantage of the exciting new possibilities made possible by the rise of e-learning as a direct result of the current environmental shift. Through reviewing a wide range of studies, theses, research, and papers published by a variety of writers in India and elsewhere, the researcher here is making an effort to glean any and all relevant information for the study. Literature can help guide the formation of research questions. Both primary and secondary sources of information are considered during the discovery process. In order to derive the research of e-learning platforms in pedagogy and professional certifications, secondary data should be gathered from many websites. Primary sources include both educators (professors and teachers) and learners (students). The material was examined and hence the following findings were produced from the study. Today’s e-learning approaches in higher education can be traced back to the original remote learning techniques. There are numerous causes for the expansion of the upper education and professional certification courses of e-learning industry, both from the institutions’ and students’ viewpoints. The researcher hopes to achieve all of the study’s aims and learn as much as possible about the topic by analysing the data gathered.
Life Cycle Assessment of Thermosyphon and PV Hot Water Systems Under the Same Operating Conditions in a Side-by-Side Experimental Setup in Namibia: Initial Results and Data Comparison with Existing Similar Installations
Authors: Kicker Harald , Wallner Gernot M. , Tschopp Daniel , Moschik Rudi , Gruber-Glatzl Wolfgang , Shigwedha Joseph , Ileka Helvi , Shidhika Fenni
Published: April 2024

The global demand for hot water is increasing, driving a shift towards solar technologies. Namibia, aligning with emission reduction goals, plans to replace electric boilers with solar thermal and PV2Heat systems, emphasizing cost efficiency. This study focuses on providing eco-performance data for solar hot water systems, specifically thermosiphon and PV systems. Three systems in a container at the NUST Science and Technology Park are being compared, with commissioning scheduled for 2024. Preliminary eco-performance data will be derived from initial monitoring, followed by a comprehensive life cycle assessment (LCA). The study envisions a straightforward process in generating input data for the LCA, including performance data. Determining the levelized cost of electricity (LCOE) for economic comparison is a key aspect. While leveraging existing data from previous works, it acknowledges the limitations in estimating expected eco-performance indicators. The study aims for a direct LCA and eco-performance comparison between solar thermal and photovoltaic-based systems, contributing to Namibia's sustainable energy strategy.
The study of indicators of the effectiveness of the implementation of the innovation policy of the state
Authors: Toshpulotov Alisher , Surina Elena , Lysikova Irina , Beseliya Alena
Published: April 2024

The uneven distribution of natural resources, the globalization of the world economy, geopolitical and socio-cultural differences force the participants of the economic system to enter into a competitive struggle. World practice shows that innovations currently occupy a leading place in the economies of developed countries: they contribute to the growth of the competitiveness of the economy, optimize its structure, reduce costs, attract external financial resources and establish the dominance of the state in the development of the leading sectors of the world economy. Creating and maintaining a competitive advantage is a highly localized process. Differences in national values, culture, economic structures, institutions and the historical past – all these factors play a role in achieving success in competition. Thus, achieving successful competitiveness of economic systems in the global market is an indisputable priority of every developed state.

Despite the fact that the study of international competition issues has a long history, interest in this problem has increased recently, since most of the world's economies have been involved in intense competition. The incentive that encourages countries to compete is the desire to surpass others. The global process is the growing competition of national innovation systems for the resources of their development. Economic development, that is, the continuous renewal of the economy as a result and as a reason for the renewal of the needs of the progress of civilization, is characterized by an increase in the feedback "economy – progress".

The article examines the interpretation of the concept of “innovative potential of the state” and studies the main indicators and indicators of the effectiveness of the implementation of the state’s innovation policy.
Retail trade as an actor of food security: functions and tools of their implementation
Authors: Mityashin Gleb
Published: April 2024

This article discusses the role and functions of food retailing in the Russian food security system. It is noted that every year more and more requirements are applied to the food security system. Using a descriptive review of the literature, it was found that the authors identify 7 groups of requirements for the product distribution system. At the same time, the main channel for the distribution of food among consumers in Russia is retail trade, which is entrusted with the functions of creating comfortable conditions for the purchase of products for various consumer groups. Despite the fact that retail trade enterprises are commercial structures, they perform a number of social functions that make the product distribution system more equitable. During the review of scientific literature and open news sources on the Internet, a number of retail initiatives were identified, including: support for the development of foodsharing, creation of shelves of goods with various organizational forms, price differentiation of stores and trade assortment (creation of discounters, introduction of cheaper and more expensive goods into the assortment, development of private labels), participation in the social programs of charitable organizations, making proposals to improve the system of distribution of products to public authorities. This study presents the characteristics of each of the mentioned areas of activity of retail trade enterprises. The article shows that the role of retail in the modern food security system is undergoing a transformation from meta-commercial sale of goods to the public to a comprehensive distribution platform for products to the public on various conditions.
Aspiracje edukacyjne młodzieży a środowisko szkolne, rodzinne i mieszkalne. Raport z badań
Authors: Wasielewski Krzysztof
Published: April 2024

Niniejszy artykuł poświęcony jest aspiracjom edukacyjnym młodzieży. Bez wątpienia to ważny rodzaj aspiracji, bo informuje nie tylko o dominujących wzorach i normach, dotyczących m.in. rynku pracy i stylu życia, lecz także o kondycji różnych grup społeczno-zawodowych, zmianach w hierarchii stratyfikacyjnej oraz otwartości struktury społecznej i samego systemu oświatowego. Artykuł opiera się na wynikach badań empirycznych zrealizowanych w dwóch znacznie różniących się pod względem charakterystyk oświatowych, gospodarczych i społecznych województwach – dolnośląskim i warmińsko-mazurskim. Badanie realizowane było za pomocą ankiety audytoryjnej w wybranych szkołach obu województw.
Potencjał kapitału społecznego lokalnych grup działania województwa łódzkiego
Authors: Hanke-Zajda Katarzyna
Published: April 2024

Wdrażanie wielofunkcyjnego i zrównoważonego modelu rozwoju obszarów wiejskich oznacza proces zmiany społecznej. Jej podmiot stanowią mieszkańcy wsi. Cechująca ich sieć współpracy, wola kooperacji, poziom zaufania, uznawane za składowe kapitału społecznego, warunkują możliwość wprowadzenia założeń paradygmatu odnowy. Tworzone m.in. w ramach programu LEADER + lokalne grupy działania i ich potencjał mogą być zaczynem, a na bardziej aktywnych społecznie obszarach „grupą wspierającą” dotychczasową współpracę mieszkańców obszarów wiejskich. Podejmowany w artykule problem dotyczy zatem potencjału kapitału społecznego LGD z województwa łódzkiego. Celem jest przedstawienie wyników badań empirycznych, które dotyczą poziomu jego komponentów: zaufania, wartości oraz sieci.
Kierunki rozwoju wsi prezentowane przez wybrane lokalne grupy działania, realizujące program LEADER+ w Polsce
Authors: Śpiewak Ruta
Published: April 2024

Za pomocą analizy treści w artykule analizowano Zintegrowaną Strategię Rozwoju Obszarów Wiejskich (ZSROW) w celu poznania wizji rozwoju oraz preferowanych kierunków i zmian na obszarach wiejskich, wskazywanych przez społeczności biorące udział w pilotażowym programie LEADER+. Przedstawiono skalę i rangę problemów, które pojawiają się w analizowanych dokumentach, oraz podjęto próbę odpowiedzi na pytanie, jakiego rodzaju strategie działania zamierzają podjąć mieszkańcy – pasywne czy aktywne. Strategia pasywna w tym kontekście może być postrzegana jako działania mieszkańców wsi podejmowane w celu walki ze swoimi słabościami (słabymi stronami), aktywna zaś jako maksymalizacja szans rozwoju (mocnych stron).
Profesor Mieczysław Adamowicz doktorem honoris causa Uniwersytetu Przyrodniczego w Lublinie
Authors: Lemanowicz Marzena
Published: April 2024

Profesor Mieczysław Adamowicz doktorem honoris causa Uniwersytetu Przyrodniczego w Lublinie.
Wnioski i rekomendacje wynikające z badań pracowników IRWiR w 2009 roku
Authors: Zawalińska Katarzyna
Published: April 2024

W 2009 roku zakończył się pierwszy okres wydatkowania funduszy unijnych na politykę rolną i rozwoju obszarów wiejskich w ramach budżetu 2004–2006. W badaniach Instytutu Rozwoju Wsi i Rolnictwa przewijało się wiele wątków, oceniających różne aspekty wdrożonych programów, w tym ich wpływ na rozwój gospodarczy, wiejski rynek pracy, ochronę środowiska, postawy rolników i mieszkańców wsi, a także zjawiska przestrzenne, towarzyszące przepływowi tych funduszy do obszarów wiejskich i na rozwój instytucjonalny, który dokonał się, aby programy te można było uruchomić i obsłużyć. Jednocześnie część badań skupiała się na umiejscowieniu tych zmian w szerszym kontekście międzynarodowym i porównywała politykę Unii Europejskiej z polityką Stanów Zjednoczonych. Najważniejsze wnioski podsumowano w kolejnych rozdziałach, a na końcu zebrano wynikające z nich rekomendacje dla polityki i praktyki rozwoju obszarów wiejskich.
Zagrożenia związane z wykonywaniem przez dzieci prac rolnych w opinii uczniów szkół wiejskich województwa kujawsko-pomorskiego
Authors: Florek Magdalena , Lachowski Stanisław , Sosnowska Stefania
Published: April 2024

W artykule podjęto próbę udzielenia odpowiedzi na pytanie czy dzieci, pochodzące ze środowiska wiejskiego odczuwają zagrożenia dla własnego zdrowia i rozwoju w związku z wykonywaniem prac rolnych. Problematykę tę przedstawiono na podstawie badań ankietowych przeprowadzonych wśród dzieci z rodzin rolniczych z dwóch powiatów województwa kujawsko-pomorskiego. Badaniami ankietowymi objęto 971 uczniów wiejskich szkół podstawowych (klasy V i VI) oraz wiejskich gimnazjów (klasy I). Z uzyskanych danych wynika, że prawie połowa uczniów nie dostrzega, by wykonywanie prac w gospodarstwie rolnym rodziców zagrażało ich zdrowiu, życiu czy rozwojowi. Większość jednak przyznaje, że prace te są niebezpieczne lub raczej niebezpieczne.
Pozycja prawna gminy wiejskiej w procedurze wyznaczania i ochrony obszarów Natura 2000
Authors: Habuda Adam
Published: April 2024

Celem artykułu jest ukazanie statusu prawnego gminy wiejskiej w procesie tworzenia i ochrony obszaru Natura 2000. Opracowanie podzielone jest na cztery części. Pierwsza dotyczy miejsca ochrony przyrody w działalności władz publicznych, w szczególności samorządu gminnego. Druga poświęcona jest uzasadnieniu wyróżnienia gminy wiejskiej spośród zasadniczo prawnie jednolitej kategorii gminy. W części trzeciej ukazana jest istota prawna obszarów Natura 2000 i charakterystyka ich tworzenia. Część czwarta dotyczy wskazania instrumentów prawnych, jakie mogą wykorzystywać gminy względem obszarów Natura 2000. Udział gminy w tworzeniu obszarów Natura 2000 oparty jest na instrumentach planistycznych i opiniodawczych. Jeżeli chodzi o ochronę obszaru już utworzonego, to kluczowe znaczenie mają instrumenty decyzyjne, związane z realizacją określonych przedsięwzięć. Organ wykonawczy gminy może brać udział w tym procesie zarówno na etapie wstępnym, gdy mowa o środowiskowych uwarunkowaniach danego przedsięwzięcia, jak i może być autorem decyzji „właściwej”, pozwalającej na realizację określonego przedsięwzięcia. Możliwa jest też taka sytuacja, iż organ wykonawczy gminy nie bierze udziału w wydaniu żadnej z wymienionych decyzji, choć przedsięwzięcie ma być realizowane na obszarze jego gminy. Powstaje wówczas pytanie o jego pozycję w takiej sytuacji - czy ma prawny status strony? Artykuł nie wyczerpuje wszystkich wątków związanych z tematem, ma za zadanie dokonać pewnej systematyzacji, uporządkowania, ukazania zjawiska w szerszej perspektywie.
Poziom rozwoju gospodarczego i społecznego gmin wiejskich regionu Zielonych Płuc Polski względem klasyfikacji obszarowej sieci Natura 2000
Authors: Stanny Monika
Published: April 2024

Celem niniejszego opracowania jest określenie poziomu rozwoju społecznego i gospodarczego gmin wiejskich Zielonych Płuc Polski i oraz ich klasyfikacja. Przeprowadzono także grupowanie gmin względem kryterium obszarowego sieci ekologicznej Natura 2000, co stało się podstawą do zbadania wewnętrznej struktury tych grup względem indykatora poziomu rozwoju. Takie ujęcie problemu doprowadziło do sformułowania następujących uogólnień: poziom rozwoju społeczno-gospodarczego, wykazuje tendencje rozwojowe w układzie centrum-peryferia; wysoki poziom oceny sytuacji gospodarczej osiągają gminy o wysokich walorach turystycznych; wyższy poziom rozwoju społecznego przypisany jest do regionów historyczno-etnograficznych (jak np. Kurpie); siła współzależności poziomu rozwoju społecznego z poziomem rozwoju gospodarczego jest większa w grupach gmin o dużym udziale obszarów objętych siecią ochrony przyrody Natura 2000; klasa o niskim poziomie rozwoju społeczno-gospodarczego posiada większy udział w gminach o małym odsetku obszarów Natura 2000, a klasa o wysokim poziomie rozwoju stanowi większy udział w grupie gmin o dużym odsetku obszarów „naturowych”.
Lettere
Authors: Selicorni Angelo , Macchiaiolo Marina , Mazzoni Elisa , Memo Luigi , Onesimo Roberta , Faravelli Fabrizio , Di Michele Silvia , Zampino Giuseppe
Published: April 2024

Una sorta di manifesto sulla gestione del bambino ad alta complessità assistenziale: unità di intenti tra i professionisti per evitare sovrapposizioni, fraintendimenti e duplicazione degli interventi.
Dermo mail
Authors: Berti Irene
Published: April 2024

Angiofibromi del volto Orticaria para-infettiva
The Final Termination: A New Chronology of Edith Wharton’s Engagement to Harry Stevens
Authors: Kalish Ilene
Published: April 2024

This article offers a new chronology for Edith Wharton’s first engagement to Harry Stevens, showing that much of the accepted understanding of this episode—namely, that it was brief, from August to October 1882, and inconsequential—is incorrect and provides the first full account of the engagement. Through a close reading of Wharton’s life writing, a re-examination of the letters in Wharton’s archive, and a review of the newspapers of the early 1880s, this article shows the couple were linked from the ball season of 1879–80 and that the engagement lasted from August 1882 to June 1883. It also details Wharton’s treatment of her debutante debut in her life writing, focusing on her moments of misdirection and omission about this time period that helped to obscure this affair from her life’s history. For the first time, a location, date, and details about the abrupt demise of the engagement are given. Further, this article provides previously unknown details about the treatment of the couple’s on-again, off-again engagement status in the society pages of the major newspapers in New York and Newport in the late spring and early summer of 1883, making this Wharton’s first sustained treatment from the press.
The Later History of the Edith Wharton Society: The Last Twenty-Three Years
Authors: Shaffer-Koros Carole M.
Published: April 2024

This article details the history of the Edith Wharton Society in the last twenty-three years.
OTTO LİMAN VON SANDERS VE ‘OSMANLI DEVLETİ’NİN ASKERİ ÇÖKÜŞÜNÜN NEDENLERİ’ BAŞLIKLI RAPORU ÜZERİNE
Authors: Ertekin Ferdi
Published: April 2024

Ordunun vaziyeti Osmanlı Devleti’nin yükseliş döneminde olduğu gibi çöküşünde de önemli yer tutar. 1877-78 Osmanlı-Rus Savaşı’ndan sonra Osmanlı Devleti, bekâsını sürdürebilmek adına orduyu modernleştirme sürecini hızlandırdı. II. Abdülhamit, 93 Harbi’nde İstanbul önlerine yürüyen Rus tehdidi karşısında, sömürgeci devletler İngiltere ve Fransa yerine Almanya ile yakınlaşmayı tercih etti. 1871’de dönemin paradigma ordusu Fransa’yı mağlup ederek siyasî birliğini kuran Almanya ile Osmanlı Devleti arasında kurulan ittifak, doğal olarak askerî alana da sirayet etti. II. Mahmut devrinde Prusya ile kurulan cılız temaslar II. Abdülhamit döneminde sağlam bir zemine kavuşarak imparatorluğu silah sanayinden askerî talim ve öğrenime değin birçok alanda Almanya’ya bağlı hale getirdi. İki devlet arasındaki bu politik ve askerî ilişkiler sonucunda Osmanlı Devleti, Almanya’nın müttefiki olarak I. Dünya Savaşı’na girdi ve mağlubiyet sonucunda ağır koşullar içeren Sevr Antlaşması’nı imzalayarak askerî ve politik olarak çöküşün eşiğine geldi. Aralık 1913’te Alman askerî misyon heyeti başkanı sıfatıyla Türkiye’ye gelen ve savaş boyunca Türk ordusunda yüksek komuta kademesinde hizmet veren Otto Liman von Sanders, savaştan sonra, İngilizler tarafından tutuklanıp Malta’ya sürgüne yollandı. Sanders, Alman makamları için mağlubiyetin nedenlerine değindiği bir rapor kaleme aldı. Bu rapor, İngiliz istihbaratı tarafından ele geçirilerek İngilizce’ye çevrildi. Bu makalede, Osmanlı Devleti ile Almanya arasında kurulan politik, askerî ve ekonomik işbirliğinin tarihi kökenlerine değinilmekte ve Sanders’ın ‘Osmanlı Devleti’nin Askeri Çöküşünün Nedenleri’ başlıklı raporu ele alınmaktadır. Türkçede ilk defa yayınlanan bu raporda Osmanlı Devleti’nin politik olarak çöküşüyle sonuçlanan I. Dünya Savaşı’ndaki mağlubiyetin nedenleri, Alman Askerî Misyon Heyeti Başkanı Liman von Sanders’ın perspektifinden ortaya konulmaktadır.
La pauvreté dans la Bible (I): D’un état de fait vers une législation de solidarité
Authors: sERBAN Tarciziu-Hristofor
Published: April 2024

This article covert from a biblical point of view a social problem of permanent interest: poverty, seen as a state of precariousness caused by the multiple causes, some involuntary (the state of people left without support – widows, orphans, those with disabilities –, victims of natural disasters, immigrants, etc.) or voluntary (greed of peers, indifference of institutions empowered to watch over the observance of citizens’ rights, etc.) that led to it. It is, however, a scandal in a society that holds a theological view that God is a Father to all members of the People, from which it implicitly follows that the latter are brothers. However, such a scandal generated positions of some of those responsible, most often under pressure from prophets. These positions gradually led to the drafting of legislative codes designed to regulate scandalous social situations. When even these regulations did not eradicate poverty, then the vision of a new, messianic project was born. This project, which has as protagonist a descendant of King David, proposes a new vision (which I will develop in a later article) foreshadowed in several prophetic texts with a messianic theme.
A case of inguinal hernia with partial bladder herniation
Authors: Philippe Niamien Nzi Jacques , Macek Sarah , Philippe Niamien Nzi Jacques , Ireland Nicole , Yoon Yong
Published: April 2024

Introduction: Inguinal hernia repairs are commonly performed, and recurrence remains one of the well-known complications. In rare cases, intra-abdominal organs can become entrapped in the hernia sac, risking incarceration and subsequent strangulation if not managed promptly.

Case Report: A 78-year-old male previously underwent bilateral inguinal hernia repair presented to the hospital with acute onset abdominal distension with associated nausea and emesis. He had noticed a progressively enlarging bulge in his left groin with fluctuating abdominal pain. Prior to his presentation, he had been struggling with incomplete voiding and frequent micturition managed unsuccessfully with tamsulosin. On examination, the patient’s abdomen was soft and non-tender, but visibly distended with a large incarcerated recurrent left inguinal hernia. The patient was admitted and subsequently underwent computed tomography (CT) abdomen and pelvis examination, which demonstrated mild distension of small bowel loops and an inguinal hernia with an encased segment of urinary bladder. The patient was managed conservatively and scheduled for an outpatient open hernia repair. Intraoperatively, multiple hernia sacs comprised of bladder were visualized extending into the suprapubic region. Each hernia sac was carefully opened and reduced without damage to the urinary bladder. Postoperatively, he recovered without complications and had complete symptom resolution.

Conclusion: This case illustrates a rare complication of a common procedure that holds significant morbidity if not managed promptly. Identification of urinary bladder involvement is essential to reduce the risk of iatrogenic bladder damage during surgical repair of an inguinal hernia and to ensure complete symptom resolution for the patient.
Eksplorasi Tantangan dan Solusi Dalam Pembelajaran Berdiferensiasi Pada Kurikulum Merdeka
Authors: Nur Rahmadani Muthaharoh  , Riya Kusmita  , M. Kurniawan  , Selvi Afitri  , Ali Iskandar Zulkarnain
Published: April 2024

Differentiated learning is a concept from the Independent Curriculum, which is expected to be able to overcome student diversity in learning. In its implementation, there are challenges faced by teachers and of course there are solutions to overcome them. This research method is a literature review (library research). The aim of this research is to explore what challenges are faced in differentiated learning and what solutions to overcome them. There are several challenges, namely: various characters that students have, different student learning styles, each student has their own interests, lack of teacher preparation to implement an independent curriculum, teacher abilities, time factors, high pressure, and expensive costs. The solutions are: organizing an even number of students, using appropriate learning strategies, knowing student interests, providing well-designed teacher training, and sufficient operational funds.

Keyword: Challenges, Solutions, Differentiated Learning, Independent Curriculum
The role of anonymity in online harmful conducts: is regulation the answer?
Authors: Ossa Monge María Francisca
Published: April 2024

The aim of this essay is to analyse the conflictive relationship between online anonymity and online harm, and whether there is a causality amongst these two features of today’s online ecosystems. Furthermore, we take a glimpse of the incipient regulation on this matter, mainly by the Digital Services Act in the EU and the Online Harms White Paper in the UK, as well as other proposed regulatory solutions given for this increasing problem for the current and new generations with the ever-expanding presence of Internet worldwide.
Placing students at the center of the learning process through the use of stem project-based education in the middle education stage - methodical guidelines for teachers
Authors: Stefanova Stanislava
Published: April 2024

The article argues for the choice of a project-based approach as the primary method to enhance interest in the subjects Man and Nature, Physics and Astronomy, Information Technologies by placing them at the center of the learning process. The article presents a good practice used in the education of students at the middle education stage, where they become the main actors. STEAM project-based learning emerges as a valuable tool for achieving positive outcomes in addressing contemporary societal needs and developing scientific literacy in students. The project discussed in this article focuses on topics outlined in the curriculum for Physics and Astronomy in 7th grade, Man and Nature in 6th grade, Technologies and Entrepreneurship in 7th grade, and Information Technology in 6th grade. It involves stages such as idea generation, planning, execution, and results discussion. This article has a methodological and practical-applied nature and can be adapted to specific situations, serving as a foundation for other educators in developing STEAM projects based on various problem-solving approaches.
Cadeia de Markov aplicada a ITUB4
Authors: Santos Roziane Sobreira dos , Alencar Maria Aparecida Fritz de
Published: April 2024

O mercado financeiro apresenta um cenário de grande incerteza e risco, sendo importante apresentar técnicas estatísticas de análise probabilística para estudar o comportamento da série ao longo do tempo. Nesse sentido, este estudo teve como objetivo apresentar a aplicação da Cadeia de Markov simples em dados de fechamento das ações do Itaú Unibanco utilizando o período de 2019 a 2021. O modelo utilizado corresponde a uma Cadeia de Markov em tempo discreto, para obter a distribuição inicial e as probabilidades de transição, permitindo descrever os estados futuros desta ação. Os dados resultaram em 209 observações, que foram divididas em 3 estados. Os resultados obtidos, permitem avaliar o comportamento da ação em relação aos preços semanais utilizando a Cadeia de Markov e sugerem considerá-la como ferramenta estatística para auxiliar na tomada de decisão.
The Force of Love and Hate in the Narrative of Joseph (Gen 37–50)
Authors: Avsenik Nabergoj Irena
Published: April 2024

The Joseph story in Genesis 37-50 is a homogeneous literary narrative, although it consists of various sources (J, E, P). The key to understanding the narrative is the statement at the beginning of the story about the special relationship of Jacob’s (Israel’s) father to his younger son Joseph and the negative reaction of Joseph’s brothers to his advantage over them: »Now Israel loved (ʼāhab) Joseph more than any of his other sons /…/ And when his brothers saw that their father loved him (kî-ʼōtô ʼāhab ’ăbîhem) more than all his brothers they hated him (wayyiśněʼû ʼōtô) /…/« (Gen 37:3-4). The article is based on a semantic and literary analysis of the structure of the narrative, which stands out for its contrasts. In revealing the literary manner of demonstrating the work of characters in their positive or negative role, we find out how much the characters act under the influence of their own desires, passions or ideals and how much their presentation is under the influence of a higher plan of history in a broader perspective of biblical theology and ethics.
Pastoral seoskih župa u novonastalim okolnostima Đakovačko-osječke nadbiskupije
Authors: Šota Stanislav
Published: April 2024

Prema popisu stanovništva 2011. i 2021. godine Đakovačko-osječka nadbiskupija izgubila je 78 885 vjernika katolika, odnosno 16,88%. Demografski slom posebno se očituje u seoskim župama. Demografski slom, ruralni egzodus, odnosno masovni odlazak seoskog stanovništva u gradove i bogatije zemlje Europske unije, u velikoj mjeri mijenjaju i utječu na vrijednosno-identitetsko-vjerničku strukturu seoskih župa. Nakon početne demografske raščlambe u radu se identificiraju novonastala obilježja župa na selu te se ukazuje na nove okolnosti u pastoralnom radu. Treći dio rada razrađuje četiri okosnice oko kojih i na kojima je potrebno graditi suvremeni pastoral u seoskim župama. To su: nedostatan broj svećenika, sinodalnost, supsidijarnost i suodgovornost te njegovanje kulture susreta u pastoralnom djelovanju, posebice osmišljavanju novih pastoralnih jedinica strukturiranih od više seoskih župa koje postaju aktivna središta sociokulturnoga, neotradicijskoga »novoseoskoga« vjerskog života, utemeljena na kapilarnom i kategorijalnom pastoralnom pristupu s ciljem stvaranja vjerske kohezije i nove vjerske identifikacije.
Sagorijevanje na poslu i socijalna podrška
Authors: Palac Nenad , Šparada Gina , Garmaz Jadranka
Published: April 2024

Rad se temelji na istraživanju više od dvjesto vjeroučitelja iz ukupno pet južnih (nad) biskupija. Cilj istraživanja bio je ispitati podložnost vjeroučitelja sagorijevanju na poslu, istražiti razinu socijalne podrške koju percipiraju te ispitati koje teme priželjkuju za obradu na stručnim skupovima. Vjeroučitelji su slobodno i anonimno pristupali ispitivanju za vrijeme odvijanja stručnog skupa 2023. godine u organizaciji AZOO-a, Katoličkoga bogoslovnog fakulteta Sveučilišta u Splitu i pet (nad)biskupijskih katehetskih ureda. Dobiveni materijali analizirani su pojedinačno pri čemu su prikupljani podatci o samoprocjeni sagorijevanja na poslu i socijalnoj podršci od strane ravnatelja, katehetskog ureda i bračnog partnera. Rezultati su izneseni na anoniman i zbirni način. Korištene su metode deskriptivne i inferencijalne statistike. Na temelju rezultata istraživanja razvidno je da vjeroučitelji pet južnih (nad)biskupija ne pokazuju zabrinjavajuće količine stresa na poslu i da osjećaju zadovoljavajući razinu socijalne podrške ravnatelja, katehetskog ureda i partnera.
Crkva pred etičkim izazovima umjetne inteligencije
Authors: Barščevski Taras
Published: April 2024

Brz razvoj umjetne inteligencije (UI) koja je ušla u gotovo sve sfere ljudskog života – od kulture i umjetnosti do obrazovanja, zdravstva, socijalnih pitanja, ekonomije, politike i svakodnevnog života – stvara nove izazove i prilike, no također nosi sa sobom značajne rizike koji mogu imati dalekosežne posljedice. Osim što UI može olakšati i ubrzati mnoge svakodnevne aktivnosti i podići kvalitetu života na višu razinu, postoji i rizik od prijetnji privatnosti, lošeg utjecaja na psihičko zdravlje i obiteljske odnose, povećanja društvenih i ekonomskih nejednakosti, kao i potencijalne zloporabe u nadzoru i vojnim primjenama, što bi moglo dovesti do tragičnih posljedica kako za planet Zemlju tako i za čovječanstvo u cjelini. Crkva, kao Majka i Učiteljica ne može ostati po strani tamo gdje se »stvara« nova slika čovjeka te »kroji« budućnost Zemlje i čovječanstva. Zato, prepoznajući svoju ulogu u brzo mijenjajućem svijetu tehnologija i umjetne inteligencije, Crkva naglašava odgovorno korištenje tehnologije u skladu s Božjom voljom i na dobrobit cijelog čovječanstva i svakog čovjeka, a posebice onih najpotrebnijih i najsiromašnijih. U ovom radu pokazujemo neke od scenarija razvoja umjetne inteligencije i važnost etičkih smjernica za sve sudionike tog procesa te kako crkveno učiteljstvo – od sv. Ivana Pavla II., pape Benedikta XVI., pa sve do pape Franje, kao i različitih vatikanskih institucija – odgovara danas na sve nove etičke izazove koje pred čovječanstvo stavlja umjetna inteligencija.
Artificial Intelligence Use in Feedback: A Qualitative Analysis
Authors: Pang Toh Yen , Kootsookos Alex , Cheng Chi-Tsun
Published: April 2024

Feedback, particularly the formative or ‘feed-forward’ type is important for students in higher education to understand their errors and improve their expression and clarity of ideas. While technology-assisted feedback modes, e.g., audio or video are prevalent, ensuring their efficacy and succinctness, particularly for non-English-speaking background (NESB) educators can be challenging. This study investigates the attitudes and experiences of NESB educators in the School of Engineering of RMIT University, with a focus on their use of AI-assisted tools for providing feedback to students in higher education settings. Utilising a survey, the researchers examined how personal and linguistic attributes influenced feedback strategies and explored the educators' perspectives on integrating AI tools, such as ChatGPT and BARD, in their teaching practice and to enhance student engagement with the feedback they received. Through thematic analysis the findings reveal that personal background and linguistic proficiency significantly influenced the provision of feedback. Furthermore, even though educators had different levels of familiarity with AI-assisted tools, there was a general consensus on the potential utility of these tools for improving feedback provision. These will require targeted staff training, careful human oversight to ensure quality and avoid bias, and customised AI training to align feedback with individual teaching styles.
Generative Artificial Intelligence and ChatGPT in Language Learning: EFL Students' Perceptions of Technology Acceptance
Authors: Vo Thi Kim Anh , Nguyen Huong
Published: April 2024

The study conducted in the centre of Vietnam in 2023 aims to explore English-majored students’ perceptions towards the application of ChatGPT in developing students’ English language. The research was grounded on the Technology Acceptance Model developed by Davis (1998) and further revised by Shoufan (2023). The quantitative approach was selected for the study with the questionnaire as the instrument. 369 English-majored students who have experienced using ChatGPT in language learning were selected for the study. The findings reveal that although students found it easy to use ChatGPT as well as perceived it as a useful tool for their language learning, they had neutral opinions on its usefulness. Furthermore, students had a high level of attitudes towards the use of ChatGPT in language learning while the negative attitudes towards it were found to be at a low level. While genders were recognised not to have impacts on students’ perceptions, class levels had significant effects on those of students It is highly recommended that teaching strategies, careful monitoring, and a balance between the use of ChatGPT and human interaction should be under consideration for an effective adoption of ChatGPT in language learning and teaching.
Use Of Natural And Traditional Medicine In Cuba: Results From The National Health Survey 2018-2019.
Authors: Perdomo- Delgado Johann , Varona Pérez Patricia , Suárez- Medina Ramón , Gonzalez- Pla Evelyn Anie , Gamez- Sanchez Donelia
Published: April 2024

Objective: To analyze the prevalence of Natural and Traditional Medicine (NTM) use in the last 12 months as per as the report from the National Health Survey (NHS), Cuba 2018-2019.
Material-Method: It was an observational, descriptive cross-sectional study that was part of the referred NHS. Socio-demographic characteristics of the survey respondents were collected (living area, gender, age, skin color, marital status, educational level and occupation). The main variable selected for this study was the prevalence of NTM use by the Cuban population in the previous 12 months.
Results: More than one out of five Cubans used NTM therapies in the previous 12 months to the NHS, Cuba 2018-2019, with a higher prevalence of use by people living in rural areas, females, the age group of 65-74 years old, a co-habited marital status, university educational level and those in retirement. Phytotherapy was the most reported NTM therapy.
Conclusion: This study analyzed for the first time the prevalence of NTM use by the Cuban population. It demonstrated that more than one out of five Cubans used NTM therapies in the previous 12 months to the NHS, Cuba 2018-2019. The characteristics of the CNHS ensure the conditions to facilitate the development of NTM and the information from this study would contribute to strengthen the integration of these treatments with conventional medicine in Cuba.
Intrinsic capacity as proposed by the World Health Organization and 30-month mortality among older adults in long-term care facilities
Authors: Valle Adriana Polachini do , Carvalho Tatiane Cristina de , Fonseca Antonio Rodrigues Bueno da , Oyan Thamires Auxiliadora , Bremenkamp Mariana Gegenheimer , Boas José Vitor Polachini do Valle Villas , Boas Paulo José Fortes Villas
Published: April 2024

Objective: To analyze the impact of intrinsic capacity on 30-month mortality among older adults living in long-term care facilities (LTCFs). Methods: Prospective cohort study with survival analysis conducted from July 2020 to December 2022 among older adults living in Brazilian LTCFs. At baseline (T0), 209 older residents were evaluated for demographic profile, clinical data (diagnosed diseases and current medications), intrinsic capacity according to ICOPE (cognitive capacity, psychological capacity, hearing capacity, visual capacity, vitality, and locomotor capacity domains), functional capacity (Katz Index of Independence in Activities of Daily Living), and frailty (FRAIL scale). At 30 months, mortality in the sample was assessed. Results: At T0, the mean age of residents was 82 (SD, 11.21) years; 65.07% were female, 94.26% were white, and 88.04% had multimorbidity. Overall, 54.07% (n = 113) of residents exhibited changes in four or more domains of intrinsic capacity, with locomotor capacity being the most commonly impaired domain (82.78%); 43.54% were completely dependent for basic activities of daily living, and 42.58% were frail. At 30-month follow-up, 33.49% (n = 70) of residents had died. Survival analysis revealed a statistically significant association between death and impairment in four or more domains of intrinsic capacity (p = 0.044). Conclusion: Impairment in four or more domains of intrinsic capacity is associated with death in LTCF residents.
Conceptualización, debates y estrategias en torno a la transformación de los cuidados:
Authors: Jiménez Valdez Elsa Ivette
Published: April 2024

El cuidado es un término ampliamente abordado y problematizado desde los feminismos, para el que no existe una única conceptualización. En este texto bosquejamos un recorrido por el desarrollo de este concepto para mostrar las defini­ciones, aportes, debates y la diversidad de estrategias con las que se busca transfor­mar su persistente feminización y superar las tensiones que su resolución tiene en nuestras sociedades. Buscamos incorporar a la genealogía del concepto tres posi­ciones que se están desarrollando desde Latinoamérica: el enfoque de derechos y políticas públicas, su politización desde la reproducción de la vida y desde el vínculo con los procesos de sanación y la crítica decolonial a la modernidad.
Análise do potencial de aproveitamento da água de chuva para uso doméstico em sistemas individuais localizados no município de Maricá-RJ
Authors: Rosas Diogo Fernandes , Faria André Alcântara de , Oliveira Flavio Giro de , Gondim Fábio Ribeiro , Carvalho Fábio Santos , Lemos Julia de Souza , Ribeiro Athila Dias Carrapatoso , Ohnuma Junior Alfredo Akira , Obraczka Marcelo
Published: April 2024

O crescimento da população mundial potencializa a necessidade em elevar a produção de alimentos, as atividades industriais de grande porte e com isso tem provocado o aumento na demanda por água para atender toda essa cadeia. Muitas regiões que apresentam baixa disponibilidade hídrica ou má gestão deste recurso, necessitam de fontes alternativas de abastecimento para suprir essa demanda que se encontra cada vez maior. O presente trabalho tem como objetivo avaliar o potencial do aproveitamento das águas pluviais para fins domésticos, a partir de sistemas de aproveitamento de água de chuva já instalados em edificações no município de Maricá – RJ. A metodologia aplicada consiste na identificação desses sistemas de aproveitamento instalados no município, análise criteriosa de dados pluviométricos para caracterizar a oferta de água na região estudada e no atendimento a demanda conforme estimativas de consumo de água não potável, observando também a capacidade e eficiência dos reservatórios, além de verificar a viabilidade econômica para possibilitar o uso dessa fonte alternativa. A pesquisa destaca que a área de estudo apresenta condições pluviométricas favoráveis à implantação de sistemas de captação e aproveitamento de águas pluviais de acordo com as médias pluviométricas encontradas na série histórica analisada na região em questão. Conclui também que políticas públicas de incentivos estimulam a instalação dos mesmos por moradores que possuem dificuldade em suprir esta demanda, tendo em vista os custos envolvidos na montagem e instalação dos sistemas, podendo ainda ser um modelo para que a pesquisa alcance outras localidades e realidades distintas, mas que compartilhem da mesma necessidade hídrica.
Repercussões da assistência de enfermagem ao portador de Alzheimer
Authors: Bezerra Anne Milane Formiga , Andrade Helena Mirelly Caldas Leite de , Castro Danielle Souza Cerqueira , Galindo Júnior José Uilson Ferreira , Nóbrega Silvana Mêre Cesário , Melo Gilvanise do Nascimento de , Brandão Elma Galdino , Gomes James Carlos Pereira , Assis Amanda Lívia Coelho de , Barbosa Suéllen Farias , Ferreira Jackson Soares
Published: April 2024

A doença de Alzheimer é uma doença que envolve muitos fatores fenotípicos, estes, podem influenciar na progressão do caso clínico do paciente. Alguns fatores de maior prevalência são idade avançada e traumatismo craniano. No entanto, a genética é o fator que mais coopera para a evolução do quadro clínico, podendo levar a morbidade e até mesmo a mortalidade. Na maioria das vezes o tratamento é lento e até irredutível, porém, em alguns casos o paciente responde bem e pode ter uma vida estável. Este estudo tem como objetivo analisar as repercussões na assistência de enfermagem ao portador de Alzheimer. Trata-se de um estudo de revisão de literatura integrativa, de cunho descritivo e exploratório, com abordagem quantitativa, realizado a partir de artigos nas bases de dados, portal da Biblioteca Virtual em Saúde (BVS), Scientific Eletronic Library Online (SciELO), Google Acadêmico e Base de Dados de Enfermagem (BDENF), com a combinação dos seguintes descritores: Assistência. Enfermagem. Alzheimer. Resultando-se em 5 artigos que atendiam aos critérios de inclusão e publicados entre 2017 e 2020. Os estudos analisados disponibilizou a evidenciação de que um dos maiores desafios dos enfermeiros com relação a Doença de Alzheimer (DA) é o déficit com um panorama sobre a doença e a assistência da família prestada ao portador. Diante de tais informações evidenciaram-se duas categorias: importância da assistência de enfermagem e capacitação dos profissionais e desafios dos familiares e cuidadores quanto ao cuidado do portador. Conclui-se que é importante ressaltar a qualificação dos profissionais para que possibilitem melhores resultados, pois o enfermeiro é a base de uma equipe multidisciplinar devendo estar embasado cientificamente sobre a doença.
O feminicídio e as políticas conservadoras de proteção à mulher em Manaus: um estudo a partir dos relatos em mídias sociais
Authors: Viana Rayane de Oliveira , Torres Iraildes Caldas
Published: April 2024

Este estudo concentra-se no tema da violência contra a mulher e seu desfecho com o feminicídio, assumindo o propósito de verificar especificamente os casos de feminicídio íntimo na cidade de Manaus registrados no ano de 2019. Buscou-se dar destaque as características desse crime cometido em contexto de violência doméstica e seus indicadores, com destaque para três casos ocorridos no referido ano, assim como, são colocados em evidência os impasses e fragilidades marcados pelo conservadorismo que incide sobre as políticas públicas demandadas pela Lei Maria da Penha, mas também como se expressa sobre a Lei do Feminicídio. A pesquisa recebeu o apoio financeiro da Fundação de Amparo à Pesquisa do Estado do Amazonas – FAPEAM. O trabalho de campo assenta-se nas abordagens qualitativas sem exclusão dos aspectos quantitativos, sob a inspiração da perspectiva histórico-crítica. Os dados foram coletados junto à Secretaria de Segurança Pública do Amazonas (SSP/AM) e ao Departamento de Pesquisa do Conselho Nacional de Justiça (CNJ). Dentre os múltiplos resultados obtidos, foi constatada a ocorrência de 09 feminicídios no ano de 2019, em Manaus, o que revela impasses nas políticas de proteção à mulher, já que alguns casos já haviam sido denunciados. Fica claro, por fim, que há ainda muito o que avançar em termos de aparato à Lei Maria da Penha, que permanece sob o manto de políticas conservadoras, engendradas por um discurso ideológico em razão de serem paternalistas e reprodutoras de desigualdades, mas que é pertinente ressaltar que acima de tudo, são produtos das lutas e reivindicações sociais.