bluuebunny/crossref_metadata_2025 huggingface dataset:
More Than Just Gene Therapy Vectors: Lentiviral Vector Pseudotypes for Serological Investigation
Authors: Toon Kamilla , Bentley Emma M. , Mattiuzzo Giada
Published: February 2021

Serological assays detecting neutralising antibodies are important for determining the immune responses following infection or vaccination and are also often considered a correlate of protection. The target of neutralising antibodies is usually located in the Envelope protein on the viral surface, which mediates cell entry. As such, presentation of the Envelope protein on a lentiviral particle represents a convenient alternative to handling of a potentially high containment virus or for those viruses with no established cell culture system. The flexibility, relative safety and, in most cases, ease of production of lentiviral pseudotypes, have led to their use in serological assays for many applications such as the evaluation of candidate vaccines, screening and characterization of anti-viral therapeutics, and sero-surveillance. Above all, the speed of production of the lentiviral pseudotypes, once the envelope sequence is published, makes them important tools in the response to viral outbreaks, as shown during the COVID-19 pandemic in 2020. In this review, we provide an overview of the landscape of the serological applications of pseudotyped lentiviral vectors, with a brief discussion on their production and batch quality analysis. Finally, we evaluate their role as surrogates for the real virus and possible alternatives.
Alternative mRNA Processing of Innate Response Pathways in Respiratory Syncytial Virus (RSV) Infection
Authors: Xu Xiaofang , Mann Morgan , Qiao Dianhua , Brasier Allan R.
Published: February 2021

The innate immune response (IIR) involves rapid genomic expression of protective interferons (IFNs) and inflammatory cytokines triggered by intracellular viral replication. Although the transcriptional control of the innate pathway is known in substantial detail, little is understood about the complexity of alternative splicing (AS) and alternative polyadenylation (APA) of mRNAs underlying the cellular IIR. In this study, we applied single-molecule, real-time (SMRT) sequencing with mRNA quantitation using short-read mRNA sequencing to characterize changes in mRNA processing in the epithelial response to respiratory syncytial virus (RSV) replication. Mock or RSV-infected human small-airway epithelial cells (hSAECs) were profiled using SMRT sequencing and the curated transcriptome analyzed by structural and quality annotation of novel transcript isoforms (SQANTI). We identified 113,082 unique isoforms; 28,561 represented full splice matches, and 45% of genes expressed six or greater AS mRNA isoforms. Identification of differentially expressed AS isoforms was accomplished by mapping a short-read RNA sequencing expression matrix to the curated transcriptome, and 905 transcripts underwent differential polyadenylation site analysis enriched in protein secretion, translation, and mRNA degradation. We focused on 355 genes showing differential isoform utilization (DIU), indicating where a new AS isoform becomes a major fraction of mRNA isoforms expressed. In pathway and network enrichment analyses, we observed that DIU transcripts are substantially enriched in cell cycle control and IIR pathways. Interestingly, the RelA/IRF7 innate regulators showed substantial DIU where major transcripts included distinct isoforms with exon occlusion, intron inclusion, and alternative transcription start site utilization. We validated the presence of RelA and IRF7 AS isoforms as well as their induction by RSV using eight isoform-specific RT-PCR assays. These isoforms were identified in both immortalized and primary small-airway epithelial cells. We concluded that the cell cycle and IIR are differentially spliced in response to RSV. These data indicate that substantial post-transcriptional complexity regulates the antiviral response.
In Vitro Evaluation of Anti-Rift Valley Fever Virus, Antioxidant and Anti-Inflammatory Activity of South African Medicinal Plant Extracts
Authors: More Garland K. , Makola Raymond T. , Prinsloo Gerhard
Published: February 2021

Rift valley fever virus (RVFV) is a mosquito-borne virus endemic to sub-Saharan African countries, and the first sporadic outbreaks outside Africa were reported in the Asia-Pacific region. There are no approved therapeutic agents available for RVFV; however, finding an effective antiviral agent against RVFV is important. This study aimed to evaluate the antiviral, antioxidant and anti-inflammatory activity of medicinal plant extracts. Twenty medicinal plants were screened for their anti-RVFV activity using the cytopathic effect (CPE) reduction method. The cytotoxicity assessment of the extracts was done before antiviral screening using the MTT assay. Antioxidant and reactive oxygen/nitrogen species’ (ROS/RNS) inhibitory activity by the extracts was investigated using non-cell-based and cell-based assays. Out of twenty plant extracts tested, eight showed significant potency against RVFV indicated by a decrease in tissue culture infectious dose (TCID50) < 105. The cytotoxicity of extracts showed inhibitory concentrations values (IC50) > 200 µg/mL for most of the extracts. The antioxidant activity and anti-inflammatory results revealed that extracts scavenged free radicals exhibiting an IC50 range of 4.12–20.41 µg/mL and suppressed the production of pro-inflammatory mediators by 60–80% in Vero cells. This study demonstrated the ability of the extracts to lower RVFV viral load and their potency to reduce free radicals.
Using AHP and Spatial Analysis to Determine Water Surface Storage Suitability in Cambodia
Authors: Ward Michael , Poleacovschi Cristina , Perez Michael
Published: February 2021

Cambodia suffers from devastating droughts in the dry season and floods in the wet season. These events’ impacts are further amplified by ineffective water resources infrastructure that cannot retain water during the dry season. Water harvesting (the collection and management of floodwater or rainwater runoff to increase water supply for domestic and agricultural use) is an approach that could improve Cambodia’s resiliency against droughts and floods. Despite the known benefits of water harvesting, there are currently few studies on water harvesting suitability in Cambodia. This research argues that suitable water harvesting sites can be identified by combining various expertise and evaluating hydrologic site conditions. Thirty-one local and USA water infrastructure experts made pairwise comparisons between essential engineering criteria: soil drainage, geologic porosity, precipitation, land cover, and slope. Then, model weights were calculated based on the comparisons. Using the model weights, a water harvesting suitability model showed that 19% of Cambodian land has high suitability, and about 13% of the land has the best suitability. This water harvesting model can help guide future water infrastructure projects to improve climate resiliency by identifying suitable sites for water harvesting reservoirs.
Jacobian Free Methods for Coupling Transport with Chemistry in Heterogenous Porous Media
Authors: Amir Laila , Kern Michel
Published: February 2021

Reactive transport plays an important role in various subsurface applications, including carbon dioxide sequestration, nuclear waste storage, biogeochemistry and the simulation of hydro–thermal reservoirs. The model couples a set of partial differential equations, describing the transport of chemical species, to nonlinear algebraic or differential equations, describing the chemical reactions. Solution methods for the resulting large nonlinear system can be either fully coupled or can iterate between transport and chemistry. This paper extends previous work by the authors where an approach based on the Newton–Krylov method applied to a reduced system has been developed. The main feature of the approach is to solve the nonlinear system in a fully coupled manner while keeping transport and chemistry modules separate. Here we extend the method in two directions. First, we take into account mineral precipitation and dissolution reactions by using an interior point Newton method, so as to avoid the usual combinatorial approach. Second, we study two-dimensional heterogeneous geometries. We show how the method can make use of an existing transport solver, used as a black box. We detail the methods and algorithms for the individual modules, and for the coupling step. We show the performance of the method on synthetic examples.
Analysis of the Arbovirosis Potential Occurrence in Dobrogea, Romania
Authors: Maftei Carmen , Bărbulescu Alina , Rugina Sorin , Nastac Cristian , Dumitru Irina
Published: February 2021

Climate change creates new challenges for preventing and protecting human health against different diseases that could appear and propagate. The Aedes albopictus mosquito species is an important vector for different diseases like dengue fever or zika. Although this species is not “indigenous” in Europe, its presence is noticed in many countries on the continent. The Ae. albopictus establishment is conditioned by the species’ characteristics and environmental factors. To assess the possible spread of Ae. albopictus in the Dobrogea region (situated in the Southeast of Romania), we conducted the following analysis: (1) Investigation of the current distribution and climatic factors favoring Ae. albopictus’ establishment in Europe; (2) Analysis of climate dynamics in Dobrogea in terms of the parameters identified at stage (1); (3) Testing the hypothesis that the climate from Dobrogea favors Ae. albopictus’ establishment in the region; (4) Building a Geographic Information System (GIS)-based model of the potential geographic distribution of Ae. albopictus in Dobrogea. Results show that the climate of Dobrogea favors the apparition of the investigated species and its proliferation.
Management of the Phosphorus–Cladophora Dynamic at a Site on Lake Ontario Using a Multi-Module Bioavailable P Model
Authors: Auer Martin , McDonald Cory , Kuczynski Anika , Huang Chenfu , Xue Pengfei
Published: February 2021

The filamentous green alga Cladophora grows to nuisance proportions in Lake Ontario. Stimulated by high phosphorus concentrations, nuisance growth results in the degradation of beaches and clogging of industrial water intakes with attendant loss of beneficial uses. We develop a multi-module bioavailable phosphorus model to examine the efficacy of phosphorus management strategies in mitigating nuisance algal growth. The model platform includes modules simulating hydrodynamics (FVCOM), phosphorus-phytoplankton dynamics (GEM) and Cladophora growth (GLCMv3). The model is applied along a 25 km stretch of the Lake Ontario nearshore, extending east from Toronto, ON and receiving effluent from three wastewater treatment plants. Simulation results identify the Duffin Creek wastewater treatment plant effluent as a driving force for nuisance conditions of Cladophora growth, as reflected in effluent bioavailable phosphorus concentrations and the dimensions of the plant’s phosphorus footprint. Simulation results demonstrate that phosphorus removal by chemically enhanced secondary treatment is insufficient to provide relief from nuisance conditions. Tertiary treatment (chemically enhanced secondary treatment with ballasted flocculation) is shown to eliminate phosphorus-saturated conditions associated with the Duffin Creek wastewater treatment plant effluent, providing local relief from nuisance conditions. Management guidance presented here has wider application at sites along the highly urbanized Canadian nearshore of Lake Ontario.
Spatio-Temporal Coupling Coordination Analysis between Urbanization and Water Resource Carrying Capacity of the Provinces in the Yellow River Basin, China
Authors: Qiao Ran , Li Huimin , Han Han
Published: February 2021

With the rapid expansion of the Chinese economy in recent years, the urbanization process of the provinces in the Yellow River Basin (YRB) has put serious pressure on the sustainability of the water resources carrying capacity (WRCC). It is necessary to analyze and diagnose the coordination state between urbanization and the WRCC. In this study, based on the Population-Economic-Social-Spatial (PESS) framework and Pressure-State-Response (PSR) model, we developed two index systems for the urbanization and WRCC, respectively. At the basis of the two index systems, the coupling coordination degree (CCD) of the two systems is calculated by applying the improved CCD model. Based on the calculated CCD for each province, the spatio-temporal analysis was performed to analyze the characteristics of CCD in the YRB. The obstacle factor model is utilized to obtain the main obstacle factors. The results show that: (1) the coordination state between the urbanization and WRCC systems was improved to some extent in 2017, compared to 2008, but there are differences in the coordination state of the different provinces in the YRB. (2) In terms of the level of urbanization, the gap between the seven provinces’ performance levels widened because urbanization grew at different rates. The WRCC system’s performance presented a fluctuating downward trend from 2008 to 2017 in the YRB. (3) The pressure subsystem had a significant impact on the two systems’ coordination state in the YRB, while the social urbanization and response subsystem had a less significant impact on the urbanization system and the WRCC system, respectively. Due to the growth of urbanization, the imbalanced development of the WRCC and urbanization has become the principal contradiction that must be solved in order to achieve sustainability in the YRB. The analysis of the coupling relationship between urbanization and WRCC may guide the policy makers in planning for realistic goals. The results provide a guide for high-quality development in the YRB.
Management of Urban Stormwater at Block-Level (MUST-B): A New Approach for Potential Analysis of Decentralized Stormwater Management Systems
Authors: Khurelbaatar Ganbaatar , van Afferden Manfred , Ueberham Maximilian , Stefan Michael , Geyler Stefan , Müller Roland A.
Published: February 2021

Cities worldwide are facing problems to mitigate the impact of urban stormwater runoff caused by the increasing occurrence of heavy rainfall events and urban re-densification. This study presents a new approach for estimating the potential of the Management of Urban STormwater at Block-level (MUST-B) by decentralized blue-green infrastructures here called low-impact developments (LIDs) for already existing urban environments. The MUST-B method was applied to a study area in the northern part of the City of Leipzig, Germany. The Study areas was divided into blocks smallest functional units and considering two different soil permeability and three different rainfall events, seven scenarios have been developed: current situation, surface infiltration, swale infiltration, trench infiltration, trough-trench infiltration, and three different combinations of extensive roof greening, trough-trench infiltration, and shaft infiltration. The LIDs have been simulated and their maximum retention/infiltration potential and the required area have been estimated together with a cost calculation. The results showed that even stormwater of a 100 year rainfall event can be fully retained and infiltrated within the blocks on a soil with low permeability (kf = 10−6 m/s). The cost and the required area for the LIDs differed depending on the scenario and responded to the soil permeability and rainfall events. It is shown that the MUST-B method allows a simple down- and up-scaling process for different urban settings and facilitates decision making for implementing decentralized blue-green-infrastructure that retain, store, and infiltrate stormwater at block level.
Integrated Charger-Inverter for High-Performance Electric Motorcycles
Authors: Tuan Vu Tran , Phattanasak Matheepot , Kreuawan Sangkla
Published: February 2021

A high-performance electric motorcycle (HPEM) integrated charger-inverter (ICI) with an induction motor (IM) is proposed in this article. Typical components are shared in drive and charge modes, resulting in savings of weight, volume, and cost. A two-stage ICI for AC induction motor powertrain with power factor correction (PFC) and battery charger functions is considered. Despite high voltage ripple on the DC link, a high bandwidth nonlinear controller can reject such a drawback and adequately provide a constant current or constant voltage charging process. The simulation results of 7 kW ICI are provided to validate the effectiveness and feasibility of the proposed system. Finite element analysis (FEA) determines the torque and losses of IM in charging mode.
ESTUDO COMPARATIVO DA EFICIÊNCIA DE PROCESSOS DE AQUISIÇÃO DE MATERIAIS UTILIZANDO O BPM PARA REDUÇÃO DO TEMPO DE CONCLUSÃO DE COMPRAS EM EMPRESA DE GRANDE PORTE
Authors: Moreira Weberty , Silva Angelo Gabriel Rodrigues da , Souza Luciano Severo de Azevedo , Marra Rodrigo Aparecido Campos
Published: February 2021

No mundo empresarial as organizações adotam modelos de processos de negócio, uma das alternativas que podem auxiliar para que se possa atingir a eficiência desejada é o gerenciamento dos processos do negócio. O presente artigo apresenta um estudo que propõe a otimização do processo de aquisição de materiais de uma empresa de grande porte, tendo como objetivo, analisar o atual processo que é executado, identificar os problemas encontrados no processo de aquisição de materiais e apresentar as possíveis melhorias garantindo que o processo seja executado de forma mais rápida e eficiente. Para a análise do processo atual e a proposta do processo otimizado será utilizada a metodologia BPM que possibilita analisar de forma holística as fases do processo de negócio e para a modelagem dos processos será utilizada a notação BPMN que permite qualquer usuário interpretar os símbolos e os fluxos de informação. Foram propostas a eliminação de tarefas que ocasionam em gargalos, reduções de handoffs e de tarefas manuais, bem como a criação de um novo tipo de tarefa. As mudanças que são apresentadas no estudo conseguiram proporcionar uma redução das atividades executadas tendo como resultado uma maior eficiência na execução do processo.
DESENVOLVIMENTO DE UM SISTEMA WEB COMO FACILITADOR DE MARCAÇÃO DE CONSULTAS NO SISTEMA PÚBLICO DE SAÚDE DE GUARULHOS PARA REDUÇÃO DE FILAS PRESENCIAIS.
Authors: Da Silva Danilo Moura , Do Nascimento Matheus Maciel , Tenorio Daniel Barboza
Published: February 2021

Desenvolvido em linguagem de programação HTML e PHP com aspectos visuais vinculados ao CSS e extensões em Java Script, o Agenda+Saúde apresenta uma interface extremamente simples e de fácil utilização para quem tem a necessidade de realizar a marcação de uma consulta em alguma UBS (Unidade Básica de Saúde) na cidade de Guarulhos utilizando o SUS (Sistema Único de Saúde), mas não tem tempo para permanecer em uma fila presencial. Com o Agenda+Saúde o usuário realiza o envio de seus dados para a UBS pela internet de uma forma rápida e prática, após o envio, basta aguardar o funcionário (a) da UBS visualizar seus dados e realizar a marcação da consulta.
Análise de conteúdo em pesquisa qualitativa
Authors: Sousa José Raul de , Santos Simone Cabral Marinho dos
Published: February 2021

Na abordagem do dinamismo de um determinado problema social, há várias técnicas de análise, dentre elas, a técnica de Análise de Conteúdo de Laurence Bardin. Neste artigo, abordamos a técnica análise de conteúdo em pesquisas qualitativas, sob a teoria desenvolvida por Bardin (2004, 2010, 2011), combinada com o modo como essa técnica foi aplicada na pesquisa de campo realizada por (SOUSA, 2019). É destacada a contextualização do estudo, o passo a passo da técnica e as particularidades de cada fase, essenciais para validação e aplicação da análise de conteúdo na pesquisa. Espera-se contribuir para esclarecer peculiaridades dessa técnica e demostrar seu modo de fazer na pesquisa qualitativa.
Roteiro Geoturístico da trilha para a Pedra do Sino (PARNASO, RJ)
Authors: Pessoa Fernando Amaro , Brito Adriel Filipe Soares , Pacheco Fabio Feler , Peixoto Maria Naíse de Oliveira , Mansur Kátia Leite
Published: February 2021

Diante da abundância de abordagens relativas à geodiversidade e de sua aproximação com unidades de conservação – especialmente parques nacionais, no Brasil – inúmeros debates emergem para se discutir como tal conhecimento possibilita a promoção de atividades turísticas e didáticas em favor de uma conscientização pública acerca do patrimônio natural. Nesse contexto, a presente pesquisa buscou contribuir com a divulgação e gestão da geodiversidade, através do aumento do senso de pertencimento e conhecimento da sociedade em relação ao meio ambiente. A partir de uma perspectiva integrada da natureza bastante evidente em trilhas, dentre os atrativos do Parque Nacional da Serra dos Órgãos (PARNASO), foi levantado, então, pontos de interesse da geodiversidade da trilha para a Pedra do Sino, assim como elaborado um roteiro geoturístico e didático a partir da interpretação ambiental. Para divulgação do roteiro, todos os pontos foram inseridos no aplicativo de navegação Wikiloc®, junto a fotos e descrições de cada ponto levantado ao longo da trilha, visando, sobretudo, um maior alcance e engajamento público. Ainda, foi realizada a qualificação e avaliação quantitativa do geossítio da Pedra do Sino, com base no Sistema de Cadastro e Quantificação de Geossítios e Sítios da Geodiversidade do Serviço Geológico do Brasil. A partir dos resultados gerados e da metodologia aplicada, o conhecimento da geodiversidade do PARNASO através das suas trilhas apresentou um expressivo potencial de divulgação científica, apoiado em propostas de interpretação ambiental que acompanham relações sistêmicas entre sociedade e natureza, e que propõe a todo momento conhecer, divulgar e conservar o patrimônio natural.
Uma visão da percepção dos mergulhadores recreativos no litoral paraibano
Authors: França Jéssica Maria Pereira de Souza , Lima Mônica da Costa , Mariano Erich de Freitas
Published: February 2021

O rápido crescimento no número de mergulhadores em ecossistemas recifais de maneira mal planejada vem causando sérios impactos ambientais.  O presente estudo analisou a percepção ambiental dos mergulhadores acerca dos ecossistemas recifais e suas atividades de mergulho. Objetivamos então conhecer/identificar e analisar preliminarmente a percepção ambiental de mergulhadores recreativos quanto a variáveis que podem causar impactos ambientais negativos em ecossistemas recifais nos principais pontos de mergulho no litoral paraibano. Para a coleta de dados foram aplicados questionários específicos envolvendo questões objetivas e discursivas repassadas em diferentes meios destinadas aos praticantes de mergulho na região. Diante dos resultados obtidos, foi possível conhecer o perfil dos mergulhadores do litoral paraibano, observando o que os atrai, suas concepções sobre os cuidados à vida marinha, atividades que realizam durante os mergulhos, como chegam aos locais, ações para minimizar os danos ao meio ambiente e formas de adquirir informações sobre os devidos cuidados. A maioria dos entrevistados está consciente quanto aos cuidados que devem ser adotados em suas atividades, o que aparenta ter relação com os altos níveis de escolaridade observados. Apesar da percepção ambiental evidenciada, existem poucas práticas educativas e informativas sobre os cuidados aos ambientes marinhos na região estudada. Apesar de parte dos mergulhadores ter consciência dos cuidados que devem ser tomados, foi possível observar que estes foram, em maioria, adquiridos por conta própria e isto ressalta a necessidade de medidas educativas. Para tanto, o conhecimento sobre percepção ambiental pode ser importante para realização de medidas visando um turismo sustentável e conservação de diversos ecossistemas.
A Pós Graduação Brasileira em Turismo e em Ecoturismo como caminho para o Desenvolvimento Sustentável
Authors: Sinay Maria Cristina Fogliatti de , Sinay Laura , Ferreira Ariane Queiroga , Braga Iluska
Published: February 2021

Os impactos do ecoturismo estão diretamente relacionados ao planejamento da atividade.  Assim sendo, a sustentabilidade da mesma depende, ao menos parcialmente, do conhecimento acadêmico-científico sobre o assunto. Neste contexto e tendo em vista a potencialidade do turismo/ecoturismo no Brasil, este trabalho tem como objetivo verificar se a insustentabilidade do ecoturismo no Brasil é influenciada pelo reduzido número de profissionais academicamente aptos a planejar e implementar adequadamente a atividade no país. O procedimento metodológico seguido no presente artigo se embasa no delineamento do panorama acadêmico-científico da pós-graduação brasileira em turismo (incluindo o mapeamento dos cursos de mestrado e doutorado na área, com identificação das disciplinas ofertadas e temas abordados) e na incidência de trabalhos acadêmico-científicos sobre ecoturismo no país (incluindo dissertações e teses, grupos de pesquisa do Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq e artigos publicados em periódicos científicos credenciados pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – CAPES com foco no Brasil).  Encontramos que o número de revistas, cursos de pós-graduação, disciplinas e dissertações acadêmicas no Brasil focados no ecoturismo é limitadíssimo. Assim, a análise do panorama atual permite concluir que a insustentabilidade do ecoturismo no Brasil é, de fato, parcialmente decorrente das limitações mencionadas.  Assim sendo, se faz necessário ampliar o número de cursos de pós-graduação em (eco)turismo e melhor distribuí-los geograficamente pelo país, sendo fundamental que os programas (existentes e a serem criados) incluam em seus projetos pedagógicos disciplinas que contemplem o ensino do ecoturismo. Estas duas ações certamente impulsionarão a pesquisa em ecoturismo, que atualmente se encontra pouco expressiva, e promoverão a sustentabilidade da atividade.
Introduction: Special Issue on Faith and Resilience
Authors: Bauer Sandy , Campbell Caroline
Published: February 2021

No abstract to introduction.
МЕТОД ВИЗНАЧЕННЯ КУТІВ СТРУЖКОУТВОРЕННЯ ПРИ МОДЕЛЮВАННІ ПРОЦЕСУ ТОЧІННЯ БУРОВОЇ КОРОНКИ
Authors: Zhuravel Oleksii
Published: February 2021

Метою роботи є розробка методики розрахунку співвідношення кутів процесу стружкоутворення з використанням моделювання напружено-деформованого стану, методу найменших квадратів та графоаналітичного методу розрахунку.Методика досліджень базується на застосуванні елементів теорії різання стосовно схеми утворення зливної стружки і моделі пластичної деформації металу з однією поверхнею зсуву при вільному різанні без наросту на передній поверхні леза. Для моделювання напружено-деформованого стану зони стружкоутворення та визначення кута зсуву використовувалось програмне забезпечення, яке базується на методі кінцевих елементів, призначення якого є аналіз двовимірної поведінки металу при різних процесах механічної обробки. Апроксимація лінійною залежністю точок поверхні зсуву матеріалу за допомогою методу найменших квадратів, отримання значень кутів зсуву матеріалу для різних параметрів обробки. Визначення графоаналітичним методом кутів внутрішнього тертя-зсуву та зовнішнього тертя-ковзання, отримання залежностей кутів стружкоутворення від швидкості різання та передньою кута леза.Результати. Розроблена методика розрахунку співвідношення кутів процесу стружкоутворення з використанням моделювання напружено-деформованого стану, методу найменших квадратів та графоаналітичного методу розрахунку. Програмна реалізація алгоритмічної моделі здійснена в середовищах DEFORM ™-2D Machining, КОМПАС-3D та Microsoft Excel.Наукова новизна. Удосконалено структурну схему алгоритму графоаналітичного розрахунку кутів процесу стружко утворення. Вперше розроблено методика розрахунку співвідношення кутів процесу стружкоутворення з використанням моделювання напружено-деформованого стану, методу найменших квадратів та графоаналітичного методу розрахунку. Практична цінність. Розроблена методика розрахунку співвідношення кутів процесу стружко утворення може застосовуватися у якості першого наближення або базису при інженерних аналізів процесу стружкоутворення. Також, результати статті можуть бути використані для автоматизації підходу до визначення раціональних режимів різання для зниження собівартості виготовленого кінцевого продукту за рахунок зниження витрат матеріалу, інструменту та підвищення якості оброблювальної поверхні.
МОДЕЛЮВАННЯ ПРОЦЕСУ ПРОКАТУВАННЯ В КЛІТЯХ ДРОТОВОГО БЛОКУ
Authors: Maksimenko Oleh , Samokhval Volodymyr , Orobtsev Andrii , Nikulin Oleksandr , Marchenko Kostiantyn
Published: February 2021

Метою роботи є дослідження впливу умов тертя в осередку деформування і режиму обтиснень на поздовжню сталість процесу та міжклітьові натяжіння розкату при прокатуванні в дротовому блоці. Методика проведення досліджень передбачала математичне моделювання процесу прокатування в клітях дротового блоку з визначенням середньої результуючої внутрішніх сил в металі, що пластично деформується, та інших параметрів процесу. Результати. Встановлено, що з збільшенням коефіцієнту тертя поздовжня сталість процесу прокатування по всій лінії дротового блоку збільшується з одночасним зменшенням питомого натяжіння розкату в міжклітьових проміжках, а при незначних змінах обтиснення в першій кліті блоку спостерігаються суттєві зміни режиму натяжіння між клітями та неоднозначні зміни показника сталості процесу прокатування. Наукова новизна отриманих результатів полягає у розробці математичної моделі процесу прокатування, яка дозволяє визначати, окрім відомих параметрів, середню результуючу поздовжніх сил в якості критерію сталості процесу, та підтвердженні можливості застосування такої моделі для дротових блоків з жорстким кінематичним зв’язком між клітями. Практична цінність результатів роботи зводиться до використання розробленої моделі, виявлених особливостей зміни параметрів по клітям блоку при розробці і удосконаленні технології прокатування катанки, а також у можливості використання моделі для коригування режимів обтиснень з метою забезпечення мінімальних міжклітьових натяжінь та сталості процесу по клітям блоку.
THE STATE OF THE TIMBER INDUSTRY COMPLEX OF THE RUSSIAN FEDERATION IN A SPARSELY FORESTED REGION ON THE EXAMPLE OF THE VORONEZH REGION
Authors: Marchuk Irina
Published: February 2021

The timber industry complex of the Russian Federation ranks fourth among all branches of the country, because in terms of forest area Russia ranks first in the world (8148895 km2), which is about 49.76% of the total area of Russia. The timber industry complex is a complex system and consists of four components (logging industry, woodworking industry, pulp and paper industry, wood chemical industry). Particular attention is paid to this industry in Eastern Siberia, Western Siberia and the Far East, because these regions have the greatest forest cover. In sparsely wooded regions, the timber industry is not a priority and little attention is paid to it, both by the state and by investors. In this article, we examined the state of the forestry complex of the Voronezh region, the forest cover of this territory is only eight percent of the entire territory of the country, all forests are protective, therefore the volume of timber is carried out thanks to sanitary felling and is about 285 thousand m3. In this region there are about 20 large and medium-sized enterprises involved in the timber industry and about 40 small private enterprises. The main problem of the timber industry complex in a low-wooded region is low-quality products, imperfection of regulatory legal acts at the regional level, and lack of investment. In this regard, measures were proposed that will contribute to the development of the timber industry complex in the low-forest region.
Comparison of Sound Pressure Level of Conventional and Modified Mufflers by using CFD Analysis
Authors:   Department of Mechanical Engineering UET, Peshawar, Pakistan, Ullah Zahoor , Ahmed Hassan ,   Department of Mechanical Engineering NED Karachi, Pakistan, Akhtar Kareem ,   Department of Mechanical Engineering UET, Peshawar, Pakistan
Published: February 2021

The reduction of noise emitted from the exhaust of internal combustion engine is a real challenge for all automotive industries. Mufflers are designed to reflect sound waves produced by the engine in such a way to cancel the effect of each other by destructive interference between the incoming waves from engine cylinder and reflected waves from the muffler of the 2 stroke motorbike engine. Numerical simulation is carried out to study the sound pressure level (SPL) and flow variable like velocity and pressure of conventional and proposed modified reactive muffler.
Design Analysis of Mini/Micro Hydro Power Generation Plants in Northern Districts of Khyber Pakhtunkhwa
Authors:   Department of Energy Management and Sustainaibility,US-Pakistan Center for Advanced Studies in Energy (USPCAS-E), UET, Peshawar, Pakistan, Asif Muhammad , Junaid Tahir ,   Department of Energy Management and Sustainaibility,US-Pakistan Center for Advanced Studies in Energy (USPCAS-E), UET, Peshawar, Pakistan, Ullah Zafar ,   Department of Energy Management and Sustainaibility,US-Pakistan Center for Advanced Studies in Energy (USPCAS-E), UET, Peshawar, Pakistan, Ullah Najeeb ,   Department of Energy Management and Sustainaibility,US-Pakistan Center for Advanced Studies in Energy (USPCAS-E), UET, Peshawar, Pakistan
Published: February 2021

Energy access in global challenge faced by more than 1 billion people. Pakistan, to address the challenge, has developed an access strategy of decentralized energy system. In northern hilly areas of the country, Hydel resource has been tapped through mini-micro hydro projects. However, the sites are remotes located in hilly terrain, making transportation of machinery a challenging task increasing initial cost. Similarly, loss of heat caused by slope in water channels and laborious construction of concrete channel in rigid and sharp rocks further aggravates the situation.
PENGARUH KEPEMIMPINAN DAN MOTIVASI TERHADAP KINERJA KELOMPOK TANI PADI PANDANWANGI (Studi Kasus di Desa Tegalega Kecamatan Warungkondang Kabupaten Cianjur)
Authors: Jatmika Rahmat Taufik Dwi , Dewi Gista Aulia
Published: February 2021

Salah satu aspek dalam peningkatan kinerja kelompok tani adalah berjalannya kepemimpinan ketua kelompok dalam kelompok tani itu sendiri. Tujuan penelitian ini: (1) untuk mengetahui pengaruh kepemimpinan terhadap kinerja kelompok tani, (2) untuk mengetahui pengaruh motivasi terhadap kinerja kelompok tani, (3) untuk mengetahui pengaruh kepemimpinan dan motivasi terhadap kinerja kelompok tani. Penelitian ini dilaksanakan dari bulan Februari sampai dengan bula Juni 2019 di Desa Tegallega Kecamatan Warungkondang. penelitian ini merupakan penelitian kuantitatif. Analisis yang digunakan yaitu deskriptif, metode pengolahan data sebagai berikut : (1) Regresi linier berganda, (2) Uji T, (3) Uji F. Berdasarkan hasil analisis regresi linier berganda menunjukan nilai 0,000 < 0,10 (α) dan nilai t hitung  1.943 lebih besar> dari ttabel 1.7032. hasil uji F menunjukan Variabel kepemimpinan dan variabel motivasi berpengaruh secara simultan dengan nilai Fhitung lebih besar> dari Ftabel sebesar 25,176 dengan nilai signifikan 0,000 terhadap kinerja. Hasil tersebut menunjukan, terdapat pengaruh yang signifikan antara kepemimpinan dan motivasi terhadap kinerja kelompok tani di Desa Tegallega Kecamatan Warungkondang.
ANALISIS TERHADAP TINDAK PIDANA PEMALSUAN DOKUMEN DAN PERSYARATAN ADMINISTRASI PERKAWINAN DIKAJI MENURUT PASAL 263 DAN PASAL 264 KITAB UNDANG-UNDANG HUKUM PIDANA
Authors: Syaripudin Pahmi
Published: February 2021

Agar suatu perkawinan dapat dicatatkan sesuai peraturan perundang-undangan yang berlaku maka masyarakat harus memenuhi persyaratan administrasi yang telah ditentukan Undang- undang Perkawinan. Dalam proses pendaftaran dan pencatatan perkawinan dapat terjadi pemalsuan dokumen dan persyaratan administrasi perkawinan.Pemalsuan dokumen dan persyaratan administrasi perkawinan yang berbentuk surat merupakan tindak pidana yang dapat diancam dengan Pasal 263 dan Pasal 264 kitab Undang-Undang Hukum pidana. Selain itu suatu perkawinan dapat dibatalkan apabila tidak memenuhi syarat dan rukunnya. Permasalahan yang diajukan dalam tesis ini adalah (1) Apakah latar belakang terjadinya tindak pidana pemalsuan dokumen dan syarat administrasi perkawinan. (2) Bagaimana dampak hukum adanya tindak pidana pemalsuan dokumen dan syarat administrasi perkawinan. (3) Upaya hukum apa yang dapat ditempuh masyarakat atas tindak pidana pemalsuan dokumen dan syarat administrasi perkawinan? Tesis ini menggunakan pendekatan penelitian hukum normatif, didasarkan pada alasan karena berkaitan dengan “Analisis Terhadap Tindak Pidana Pemalsuan dokumen dan Persyaratan Administrasi Perkawinan Dikaji Menurut Pasal 263 dan Pasal 264 Kitab Undang-Undang Hukum Pidana.” Dari hasil penelitian menunjukkan bahwa latar belakang terjadinya tindak pidana pemalsuan dokumen dan syarat administrasi perkawinan adalah Surat-surat tidak lengkap, calon mempelai masih dibawah umur, salah satu calon masih terikat perkawinan dengan pihak lain dan tertipu pihak lain. Tindak pidana pemalsuan dokumen dan syarat administrasi perkawinan dapat berakibat pada dituntutnya pelaku dengan Pasal 263 dan Pasal 264 KUHP dan juga dapat berakibat batalnya perkawinan.(3) kemudian masyarakat yang dirugikan dapat menempuh jalur hukum sesuai perundang-undangan yang berlaku.
UJI ORGANOLEPTIK FORMULASI FORTIFIKASI BEKATUL DALAM PEMBUATAN BUBUR INSTAN BERAS PANDANWANGI
Authors: Trihaditia Riza , Puspitasari De Trisni Khoerunnisa
Published: February 2021

Bekatul merupakan hasil limbah dari padi yang memiliki kandungan gizi yang sangat tinggi dan baik untuk kesehatan tubuh seperti aktivitas antioksidan, aktivitas kemopreventif kanker, aktivitas hipokolestrolemik dan lain-lain. Namun biasanya,  bekatul hanya dimanfaatkan untuk pakan ternak saja karena rasa dan bau khas bekatul yang tidak disukai. Dengan aroma khas pandan dalam beras Pandanwangi diharapkan dapat menyamarkan bekatul dari bau tengik. Penelitian ini bertujuan untuk mengetahui pengaruh mutu organoleptik serta respon panelis pada fortifikasi bekatul pada pembuatan bubur instan beras Pandanwangi sebagai diversifikasi pangan. Data diolah menggunakan metode RSM (Response Surface Method) yang melibatkan 30 orang panelis biasa dan 1 orang panelis ahli dengan parameter yang diujikan yaitu meliputi warna, aroma, tekstur, dan rasa. Masing-masing panelis diberikan  5 sampel yang berbeda pada setiap formulasinya yaitu F1 (beras Pandanwangi 100%: Bekatul 10%), F2 ( beras Pandanwangi 100%: Bekatul 20%), F3 (beras Pandanwangi 100%: Bekatul 30%), F4 (beras Pandanwangi 100%: Bekatul 40%), dan F5 (beras Pandanwangi 100%: Bekatul 50%). Sedangkan untuk keseluruhan dari parameter warna, aroma, tekstur, dan rasa yang paling diminati yaitu pada sampel (beras Pandanwangi 100%: Bekatul 50%) dengan nilai optimasi masing-masing 3, 3, 1, dan 3.
IDENTIFIKASI MORFOLOGI CENDAWAN ENTOMOPATOGEN Beauveria bassiana DAN Metarhizium anisopliae ASAL TANAMAN PADI CIANJUR
Authors: Sari Widya , Rosmeita Chindy Nur
Published: February 2021

Cendawan entomopatogen asal tanaman padi Cianjur sudah lama ditemukan, namun belum pernah dilakukan karakterisasi morfologi pada isolat-isolat tersebut.  Perbedaan karakter morfologi cendawan entomopatogen seperti warna koloni dan bentuk konidia, jumlah konidia dan laju pertumbuhan sangat mempengaruhi virulensi cendawan entomopatogen terhadap serangga hama sasaran. Tujuan penelitian ini yaitu untuk mengetahui perbedaan karakter morfologi cendawan entomopatogen asal tanaman padi Cianjur yaitu Beauveria bassiana dan Metarhizium anisopliae dengan isolat cendawan entomopatogen yang berasal dari tanaman yang berbeda. Penelitian ini dilakukan di Laboratorium Biokontrol dan Laboratorium Mikologi Balai Penelitian Tanaman Hias Cianjur dari bulan November 2018 sampai Desember 2018. Penelitian dilakukan secara obsevasi dan analisis deskriptif untuk membandingkan karakter morfologi dari beberapa isolat cendawan entomopatogen Beauveria bassiana dan Metarhizium anisoplie asal tanaman padi Cianjur koleksi dengan kontrol B. bassiana asal tanaman Pisang dan M. anisopliae asal tanaman Jagung.  Hasil pengamatan laju pertumbuhan cendawan tertinggi dihasilkan oleh isolat cendawan B. bassiana asal tanaman Padi, dengan rata-rata laju pertumbuhan 0,1-0,7 cm per hari.  Warna koloni cendawan B. bassiana asal tanaman Padi adalah warna putih dan B. bassiana asal tanaman Pisang berwarna putih kekuningan. M. anisopliae mempunyai warna yang sama antara isolat asal tanaman padi dengan asal tanaman jagung yaitu berwarna hijau zaitun. Cendawan B. bassiana mempunyai konidiofor yang bercabang dengan pola zig-zag dan pada bagian ujungnya terbentuk konidia yang bulat hialin. Metarhizium anisopliae mempunyai miselium yang bersekat, konidiofor bersusun tegak, berlapis dan bercabang yang dipenuhi konidia berbentuk bulat silinder. Rata-rata kerapatan konidia cendawan B. bassiana lebih rendah (3,65 x 106) dibandingkan kerapatan konidia cendawan M. anisopliae (5,80 x 106). Karakter morfologi cendawan sangat dipengaruhi oleh jenis species dan asal isolat.
PENENTUAN FORMULASI TEPUNG DAN EKSTRAK INULIN UMBI DAHLIA TERHADAP MAKANAN FUNGSIONAL BUBUR INSTAN BERAS PANDANWANGI
Authors: Trihaditia Riza , Sundayati Tammy Tri
Published: February 2021

Makanan fungsional merupakan salah satu pangan yang memiliki nilai fungsi yang tinggi namun selalu lemah dalam aspek organoleptik. Salah satu makanan fungsional yang dapat dikembangkan adalah bubur instan beras Pandanwangi berfortifikasi. Fortifikan yang dapat ditambahkan dalam bubur instan beras Pandanwangi adalah inulin yang berasal dari tanaman umbi dahlia. Tujuan dari penelitian ini adalah untuk mengetahui formulasi optimal yang akan diminati panelis. Penelitian ini bersifat eksperimental yang memanfaatkan umbi dahlia sebagai bahan utama dan beras Pandanwangi sebagai bahan dasar dengan menggunakan 4 variasi formula yang diuji menggunakan RSM (Response Surface Methode). Formula 1 (F1): beras Pandanwangi + 10 g tepung umbi dahlia, F2: beras Pandanwangi, F3: beras Pandanwangi + 10 g ekstrak inulin, dan F4: beras Pandanwangi + 5 g tepung umbi dahlia + 5 g ekstrak inulin. Pengujian organoleptik dilakukan oleh 24 orang panelis tidak terlatih dan 1 orang panelis ahli dengan parameter pengujian terdiri dari warna, rasa, aroma dan, tekstur. Hasil penelitian ini menunjukkan bahwa makanan fungsional berupa bubur instan beras Pandanwangi dengan penambahan umbi dahlia dalam bentuk tepung (F1) merupakan formula yang paling diminati panelis.
IDENTIFIKASI MORFOLOGI BENIH PADI SAWAH VARIETAS PANDANWANGI DI LIMA LOKAS KECAMATAN
Authors: Imansyah Angga Adriana , Andreyuni Frilynthia Dwi Ayu
Published: February 2021

Pandanwangi merupakan padi varietas lokal di Kabupaten Cianjur, namun tidak semua wilayah di Kabupaten Cianjur dapat ditanami padi Pandanwangi dengan ciri khas tertentu, oleh karena itu untuk menanam padi Pandanwangi diperlukan persyaratan topografi yang spesifik tanpa menghilangkan karater dan kualitas benih padi Pandanwangi. Penelitian dilakukan di Laboratorium Vocational Education Development Centre and Agriculture (VEDCA) Cianjur pada bulan Februari sampai Maret 2018. Penelitian ini bertujuan untuk menentukan karakteristik morfologi benih pada lima lokasi yaitu Kecamatan Warungkondang, Cugenang, Mande, Cianjur, Campaka serta membandingkan identifikasi morfologi benih dengan hasil deskripsi umum morfologi benih padi Pandanwangi. Rancangan yang digunakan untuk data kuantitas menggunakan Rancangan Acak Lengkap (RAK) non faktorial dengan 5 perlakuan dan 5 ulangan. Masing-masing perlakuan yaitu benih padi Pandanwangi yang berlokasi A (Warungkondang), B (Cugenang), C (Cianjur), D (Campaka) dan E (Mande). Parameter yang diamati meliputi benih murni, benih tanaman lain, kotoran benih dan bobot 1000 butir benih padi Pandanwangi, sedangkan untuk data kualitas yaitu identifikasi morfologi benih di lima lokasi Kecamatan menggunakan analisis deskripsi lalu dibandingkan dengan deskripsi umum morfologi benih padi Pandanwangi. Hasil penelitian menunjukkan bahwa identifikasi morfologi benih di lima lokasi Kecamatan yang terbaik pada perlakuan di lokasi Kecamatan Warungkondang, namun Kecamatan Cugenang, Kecamatan Cianjur dan Campaka lebih baik dibanding Kecamatan Mande.
INVENTARISASI PENYAKIT PADA DUA VARIETAS LOKAL BAWANG MERAH (Allium ascalonicum L.) BIMA BREBES DAN TRISULA
Authors: Sari Widya , Inayah Siti Aulia
Published: February 2021

Serangan patogen tumbuhan merupakan salah satu kendala yang di hadapi dalam budidaya bawang merah, beberapa diantaranya yaitu cendawan, bakteri, dan virus yang mampu menurunkan hasil produksi bawang merah. Varietas bawang Bima Brebes merupakan varietas yang paling disukai oleh petani dan adaptif pada dataran rendah sedangkan Varietas Trisula merupakan varietas yang bisa ditanam di luar musim ( off season), sehingga bisa ditanam pada musim penghujan dan adaptif pada dataran rendah. Tujuan dari penelititan ini adalah untuk mengetahui jenis dan gejala penyakit pada tanaman bawang merah varietas Bima Brebes dan varietas Trisula yang ditanam di dataran tinggi. Penelitian ini dilakukan di Balai Penelitian Tanaman Hias (BALITHI) Kabupaten cianjur, Provinsi Jawa Barat pada bulan Agustus-September 2019. Metode yang digunakan dalam penelitian ini adalah metode observasi yang dilakukan terhadap tanaman bawang merah varietas Bima Brebes dan  Trisula.  Inventarisasi penyakit dilakukan dengan pengamatan gejala serangan patogen pada daun, umbi maupun akar tanaman bawang merah. Hasil penelitian menunjukkan  penyakit yang menginfeksi pada varietas Bima Brebes yaitu penyakit Bercak Ungu pada daun yang di sebabkan oleh cendawan (Alltenaria porri), dan penyakit mosaik kuning yang di sebabkan oleh virus (OnionYellow Dwarf Virus) pada bagian daun tua.Sedangkan penyakit yang menginfeksi pada varietas Trisula yaitu penyakit Moler yang disebabkan oleh cendawan Fusarium oxysporum f.sp.cepae, penyakit Bercak Ungu yang disebabkan oleh cendawan (Alltenaria porri), dan penyakit Mosaik Kuning yang di sebabkan oleh (Onion Yellow Dwarf Virus). Varietas Bima Brebes lebih tahan terhadap infeksi cendawan Fusarium oxysporum f.sp.cepae  dibanding varietas Trisula.
PENGUJIAN BEBERAPA KONSENTRASI CUKA KAYU TERHADAP PERTUMBUHAN DAN HASIL TANAMAN KACANG EDAMAME (Glycine max (L) Merill)
Authors: , Ramli , Sari Widya , Nuryanah Ina
Published: February 2021

Kedelai edamame atau kedelai sayur termasuk spesies (Glycine max (L). Merill) ini merupakan jenis bahan makanan yang populer sebagai makanan ringan maupun bahan campuran makanan. Cuka kayu dapat berfungsi untuk mempercepat pertumbuhan tanaman, inhibitor (pencegah hama dan penyakit). Tujuan dari penelitian ini adalah untuk mengetahui apakah konsentrasi cuka kayu berpengaruh terhadap pertumbuhan dan hasil tanaman kacang edamame. Penelitian ini dilaksanakan pada bulan Februari hingga Maret 2020. Kegiatan penelitian ini dilaksanakan di kebun percobaan di Kp. Longkewang Desa Gasol Cugenang Cianjur. Rancangan percobaan yang digunakan dalam penelitian ini adalah (RAL) dengan 6 perlakuan 3 ulangan pada setiap perlakuan terdiri dari 4 unit sehingga dihasilkan 72 unit percobaan. Hasil pengolahan data secara statistik menyatakan bahwa pemberian konsentrasi (T5) = 5ml/1L air berpengaruh terhadap parameter pertumbuhan tanaman Edamame, dengan rata-rata tinggi tanaman paling baik 50,10 cm, warna daun 5,00, jumlah bunga 18,25, jumlah bintil akar 18,25 biji dan berat buah 15,55 gr. Akan tetapi konsentrasi cuka kayu tidak berpengaruh beda nyata terhadap jumlah daun tanam edamame