bluuebunny/crossref_metadata_2025 huggingface dataset:
Has high quality economic development alleviated Multidimensional relative poverty?
Authors: Shu Wei-jia , Zhou Yuan-hang , Che Si-fang
Published: December 2024

Alleviating Multidimensional relative poverty(MRP) is indispensable for achieving Chinese modernization. Utilizing the Chinese Family Panel Studies(CFPS) data spanning from 2014 to 2022, we constructed an evaluation index system for both MRP and high-quality economic development(EHD) levels. Furthermore, we introduced the BP neural network method for precise measurement of these development levels. Concurrently, we analyzed the influence and underlying mechanisms of EHD on MRP from both theoretical and empirical perspectives. Our research findings indicate the following: (ⅰ) EHD significantly mitigates the issue of MRP. This conclusion remains valid after conducting robustness tests and addressing endogeneity concerns. (ⅱ) Heterogeneity analysis reveals that the impact of EHD exhibits significant variability on MRP. Specifically, it has a more pronounced inhibitory effect on younger age groups, those with low social capital, rural residents, and low-income groups. (ⅲ) Mechanism analysis demonstrates that EHD can alleviate MRP by fostering the development of digital inclusive finance, enhancing infrastructure construction, and increasing employment opportunities. This study offers valuable theoretical insights and decision-making references for addressing MRP.
Peningkatan Hasil Belajar Menulis Teks Laporan Hasil Observasi Melalui Metode Field Trip Siswa Kelas VIII D SMP Negeri 5 Surakarta
Authors: Septia Shofi Dian
Published: December 2024

This Classroom Action Research (PTK) aims to improve the quality of learning outcomes in writing observation report texts for class VIII D students at SMP Negeri 5 Surakarta using the field trip method. The subjects of this research were 32 students in class VIII D of SMP N 5 Surakarta for the 2024/2025 academic year, consisting of 18 male students and 14 female students. The object of this research is the ability to write text reports on student observations through the implementation of the learning model Project Based Learning and field trip method. This research was designed in two cycles, namely cycle I and cycle II. The success criteria for this research are determined based on students' achievement of grades in accordance with (KKTP), which was set at 78. The research results showed that learning using the field trip method in cycle I and cycle II succeeded in improving students' writing learning outcomes in compiling the text of the Observation Result Report (LHO). This is proven by the increase in the average student score from 71.5 with a percentage of 41% in cycle I, to 84.6 with a percentage of 81% in cycle II.
RAINFALL VARIABILITY IN THE PLATEAU REGION OF TOGO
Authors:   Research and Expertise Center on the Dynamics of Spaces and Societies (PREDES), University of Kara., Pyalo Atina Badameli
Published: December 2024

The Plateau region of Togo is classified under the Guinean tropical climate based on its latitude. Therefore, it should experience two rainy seasons and two dry seasons. However, a rainfall study of the stations in this region reveals a distinct characteristic compared to other stations in southern Togo. The question arises as to whether the evolving rainfall patterns in the region align with the previous classification. The aim of this study is to identify factors for a new categorization of rainfall amounts in the Plateau region of Togo. The data used for the study include rainfall amounts from the AtakpamÃ© and Kouma-Konda stations to examine the evolution of rainfall over time and track the dynamics of the seasons. The rainfall data from the Tabligbo and Niamtougou stations are used for comparison. The construction of Gaussen diagrams is the primary method employed to monitor the distribution of rainy and dry seasons over time. The results indicate that the four seasons (two rainy and two dry) are gradually being replaced by two seasons (one rainy and one dry). Thus, the Guinean tropical climate shows a trend of shifting toward a Sudanian tropical climate in the Plateau region of Togo.
HIP INVOLVEMENT IN SPONDYLOARTHRITIS: PREVALENCE AND CHARACTERISTICS FROM A SINGLE RHEUMATOLOGY OUTPATIENTS CENTRE
Authors:   Professor of Rheumatology, Av. Mohamed V, Rue Bait Lahm, Imm B, nÂ°6 Mohamed V University Rabat, Morocco., El Maghraoui Abdellah
Published: December 2024

Hip involvement is a well-recognized feature of axial spondyloarthritis (AS). This study aimed to assess the prevalence of hip involvement and its relationship with both symptomatic and structural severity in a cohort of AS patients treated in an outpatient rheumatology clinic.Methods: A retrospective, single-center study (2019â€“2023) included confirmed AS patients. Hip involvement was defined as hip pain related to AS-driven inflammation, confirmed by radiographic imaging (BASRI-hip score of â‰¥2). Demographic data and parameters of both symptomatic and structural severity were collected. The risk of hip involvement based on disease duration was evaluated using Kaplan-Meier analysis.

Results: Among 137 AS patients, 89 (64.9%) were men and 48 (35.0) were women. The mean age was 42.2 years Â± 14 (range: 18â€“76), and the mean disease duration was 7.5 years Â± 9.1 (range: 0.5â€“38). Radiographic evidence of hip involvement was present in 19 patients (13.9%): unilateral in 9 patients (6.6%), and bilateral in 10 patients (7.3%). Hip involvement was more common in men, those with longer disease duration, and those with a higher incidence of uveitis. Patients with hip involvement exhibited higher symptomatic (BASDAI and ASDAS) and structural (mSASS) severity scores. By disease duration, 18.6% of male patients had hip involvement after 10 years, rising to 48.8% after 20 years.

Conclusion: Hip involvement is a frequent manifestation of AS, often presenting bilaterally and associated with longer disease duration and greater disease severity. However, its prevalence appears lower in outpatient settings compared to university hospital series.
Leveraging employee relationship management to foster agility: The mediating role of employee empowerment in the Indian banking sector
Authors: Naik Abhisha , De’Silva Ricovero , Kolamker Prachi , Gaonkar Vishal , Alarnkar Aakruthi , Naik Sujal
Published: December 2024

Organizational agility is a prerequisite for ensuring enhanced corporate performance in the face of technological developments. However, the supplementary role of employee relations and empowerment practices in organizational agility has not been widely explored. FinTech introduction in the banking sector has added to its already dynamic work environment. The study aimed to investigate the effect of Employee Relationship Management (ERM) on Organizational Agility (OA) & Employee Empowerment (EE), and Employee Empowerment on Organizational Agility, and evaluate whether EE has a mediating effect on the relationship between ERM and OA. Structural Equation Modelling over the SmartPLS4 software was used for analysis. A structured questionnaire was distributed to 200 employees in back-office operations departments of the top four banks with the highest market capitalization on the National Stock Exchange, India. Employees from branches operating in metropolitan cities were selected. Results underscore the human asset’s prominence in the banking sector’s sustenance, showing a significant positive direct effect of EE on OA (P value: 0.000, Path Coefficient: 0.627), ERM on OA (P value: 0.025, Path Coefficient: 0.718), and on EE (P value: 0.000, Path Coefficient: 0.718). EE also shows a mediating effect in the influence of ERM over OA (P value: 0.000, Path coefficient: 0.45).The results bridge the gap in knowledge about the prominence of the Resource-Based Theory by investigating the role of employees in enhancing the banking sector’s ability to adjust operations in line with technological advancements.
The role of business transformation strategy in Indonesian regional development banks
Authors: Thuda Audy , Hamsal Mohammad , Leonarda Warganegara Dezie , Heriyati Pantri
Published: December 2024

Rapid advances in technology and shifting customer expectations have intensified competition in the financial industry, forcing Indonesia’s banking sector to adopt adaptive and innovative strategies to remain competitive in an increasingly complex and uncertain environment. This study investigates the role of business transformation strategy in organizational performance. Employing a quantitative approach using Structural Equation Modeling (SEM), the study analyzes data collected from 255 Branch Managers across 27 Regional Development Banks in Indonesia. The coefficient of determination for the business transformation strategy was 0.69, indicating that 69% of its variance could be explained by environmental dynamism, transformational leadership, talent development, and digital adoption. Similarly, the R2 value for organizational performance was 0.51, indicating that digital adoption and business transformation strategy accounted for 51% of its variance. The findings reveal that environmental dynamism (t-value 1.85) and talent development (t-value 1.58) do not positively affect business transformation strategy. Instead, transformational leadership (t-value 2.38) and digital adoption (t-value 4.28) positively affect business transformational strategy. Furthermore, business transformation strategy (t-value 3.10) positively affects organizational performance. Meanwhile, business transformation strategy does not mediate the influences of environmental dynamism, talent development, and transformational leadership on organizational performance but strongly mediates digital adoption. This study emphasizes that business transformation strategy is the cornerstone for aligning digital adoption and leadership approaches to drive organizational performance. This study contributes to understanding business transformation strategy in the banking industry by providing technology-driven strategic insights from Indonesian Regional Development Banks.
Examining the nexus of infrastructure development and economic growth: Evidence from SAARC countries
Authors: Khandelwal Vinay , Chotia Varun , Sharma Prashant , Soni Swati , Kalyani Sushil
Published: December 2024

This study investigates the interconnected roles of infrastructure development, financial growth, and economic growth in SAARC nations. Using principal component analysis, the paper develops a composite infrastructure development index, which integrates factors such as access to electricity, telecommunications, air transport, and agricultural land use. This index serves as a comprehensive measure to assess and compare infrastructural progress across the region. Econometric analyses, including Pedroni’s and Kao’s cointegration tests, reveal long-term associations between the studied variables. The results demonstrate a bidirectional relationship between trade openness and GDP growth in the short term, as well as unidirectional influences from inflation to financial development and from infrastructure development to inflation. However, findings vary across SAARC countries, reflecting their diverse economic structures and development stages. Notably, Afghanistan is excluded due to data limitations, emphasizing the region-specific focus of the results. The study highlights the critical role of targeted infrastructure investment and financial sector reforms in fostering sustainable economic growth. Policymakers are encouraged to consider these findings when designing synchronized public and private sector initiatives to bridge development gaps. By offering detailed insights into region-specific dynamics, this study enriches understanding of the complex interplay between infrastructure, finance, and economic growth in emerging economies.
Individualized recommending exercises and improving DINA algorithm by CLP-parameter adjustments
Authors: Liu Yuhan , Liu Wei , Yu Jianxing , Yin Jian
Published: December 2024

The traditional mode of education has been integrated with the technologies of internet to give rise to smart and or intelligent assistant education. A recommender “recommending items to customers” has been applied with great success in many commercial platforms, such as Amazon, Google, JD.com, and Tiktok, but there still has been no such an assisted learning system that effectively “recommending exercises (as the items) to learners (as the customers)”. This paper addresses the problems and challenges in applying recommender technology to the design of an intelligence-assisted learning system for individualized exercises recommendation. After providing an overview with some analysis on state-of-the-art researches, a model is proposed to improve DINA algorithm by four adjustments with changeable parameters of cognitive level perception (CLP), together with three primary steps of implementation in practice. It aims to improve recommendation accuracy of the mostly-concerned DINA algorithm based on widely-concerned cognitive diagnosis method (CDM). The proposed algorithm would have better performances on individualized exercises recommendation due to better CLP-capability. Another part of this study will provide further verification of the performances.
Experimental optimal control of servo-pneumatic with sliding mode and GA-fuzzy-PID-PWM
Authors: Siavashi M. , Hasanlu M.
Published: December 2024

Due to the inherent nonlinearity of pneumatic systems, achieving accurate control of pneumatic actuators remains a challenging task. This study compares three control strategies-PID control, fuzzy control, and sliding mode control-used to guide the motion of pneumatic actuators driven by on/off solenoid valves. The primary objective is to evaluate and compare the performance of each controller in the context of servo-pneumatic systems, highlighting their respective advantages and disadvantages. On/off solenoid valves, which reduce system costs, are utilized in this study. Since these valves can only process on/off signals, pulse width modulation (PWM) is employed to modulate the input signal, adjusting the duty cycle and performance time of the valves. Initially, the governing equations for the actuator and valves are presented, followed by an introduction to each controller. The pulse width modulation algorithm is then discussed, which regulates the control signal to the valve’s duty cycle and performance time. Finally, simulation results are provided, comparing the controllers and illustrating their strengths and weaknesses.
Study on dynamic response analysis and vibration control of TV tower under wind-rain load excitation
Authors: Li Na , Cheng Zhengquan
Published: December 2024

This study thoroughly examines the impact of the coupling effects of wind-rain load on the structural behavior of the television tower, and the effective vibration control method is employed to mitigate the dynamic response of the structure. A refined finite element model of the tower was developed, and the dynamic response characteristics of the structure under varying wind speeds and rain intensities are further investigated. Based on parameter analysis, the influence of mass ratio and frequency ratio on the damping efficiency of tuned mass damper (TMD) was revealed. The results demonstrate that compared to wind load alone, the node displacement increases more significantly near the top of the tower under wind-rain load. When the basic wind speed reaches 40 m/s, the TV tower will be damaged due to the extreme compressive stress of the 45 units on the compression side exceeding the yield strength of the members. Under extreme weather loads, the members on the compressive side at a height of 60 meters are most susceptible to yielding and entering the plastic deformation stage. The overall vibration reduction effectiveness of TMD increases with higher mass ratios, with a mass ratio of 1.5 % identified as optimal. Regarding the reduction of top displacement of the tower, the effectiveness of TMD varies with frequency ratio, showing an initial increase followed by a decrease; optimal vibration control is observed at a frequency ratio of 0.9.
Formation of Local Organs of Russian Communist Party of Bolsheviks in Tomsk Province in late 1919 – 1921
Authors: Kurenkov Artem V.
Published: December 2024

The first local organs of the Russian Communist Party of Bolsheviks appeared in the Tomsk Province on various territorial levels after Kolchak’s troops had left it. As Soviet power returned to the region, the underground Bolsheviks and Red Army representatives started to organize communist meetings to elect party bureaus and committees. They were temporary party organs that functioned until party conferences could officially be held in accordance with the Charter of the Russian Communist Party of Bolsheviks. The Tomsk provincial committee was the largest one: it participated in the life of smaller, district committees by selecting party candidates. The lower level included local committees, which either had the power of district committees or were subordinate to them. The local committees could be urban or rural. The volost party committees were subordinate to the district committees or local committees. They were formed through election by the peasant population at volost party conferences and congresses. If the political and socio-economic situation made it impossible to organize elections, the volost committees were appointed by the local committees or district committees. The cells were the bottom link in the party hierarchy. They were formed at general meetings of members and candidates for party membership and approved by the district party committees. The rural cells could be organized by the peasant population or appointed by the political workers of military units and instructors of higher party organs. The development of local organs of the Russian Communist Party of Bolsheviks in the Tomsk province was complicated by the constant lack of party workers. Severe staff shortages were typical of all party organizations in the province at all levels and had a negative impact on the party work. Attempts by the provincial committee to resolve the situation were futile. As a result of the personnel problem, Novonikolaevsk and Tomsk were the only urban settlements with their own urban party committees in the province.
Joseph Stalin’s Death as Perceived by Soviet Citizens: Materials from the Kemerovo Region
Authors: Morozov Dmitry S.
Published: December 2024

The article describes the way the population of the Kemerovo Region responded to the death of Joseph Stalin at mourning events as a projection of the Soviet myth. The author studied verbal and non-verbal reactions to identify the main concepts and patterns used by the local people to describe their psycho-emotional and mental state after receiving the news of Stalin’s death. The content and discourse analyses revealed the following verbal reactions: "shared loss" and "personal grief"; Stalin as a father figure, personifying the paternalistic attitude of the Soviet state towards its citizens; a connection between Stalin and the achievements of the entire country; appeals to citizens to strengthen production and political activity, to support the government; "immortality" of Stalin, his system, and Soviet achievements, and the "eternal significance" of his ideas. The non-verbal reactions included a total mobilization of political and production activities to consolidate people around the party and state institutions. In general, people’s response to Stalin’s death could be reduced to a reproduction of certain patterns that reflected the main ideologemes of the Soviet myth.
Anti-Cosmopolitan Campaign in the USSR: Russian Historiography in 2010s – Early 2020s
Authors: Genina Elena S. , Ovchinnikov Vladislav A.
Published: December 2024

The article describes the recent Russian historiography (2010s – early 2020s) on the anti-cosmopolitan campaign launched by the Soviet authorities in 1949–1953. The research relied on the principles of historicism and objectivity. The authors used the methods of comparative-historical and problem-chronological research, retrospective and prospective analyses, and periodization to identify the research areas that keep attracting modern Russian historians. The latter seem to pursue the following problems and topics: the authorities vs. the Soviet intelligentsia; the Doctors’ Plot (1953); the state policy against Jewish communities; the anti-cosmopolitan campaign in provincial regions. The relationship between the authorities and the Soviet intelligentsia proved to be the most popular topic. The authors identified the main approaches that modern Russian historians applied to this topic. In addition, they compared the most recent Russian historiography with earlier research data to identify the topics that still maintain their debatable nature. Modern historians seem to focus on the anti-cosmopolitan campaign in peripheral Soviet regions. Apparently, the ethnic regions of the RSFSR interpreted the campaign in their own ways. The regional specifics of the anti-cosmopolitan campaign still need comprehensive research. Another promising direction is represented by biographical reconstructions of the repressed Soviet intelligentsia.
Degradation of aliphatic and aromatic hydrocarbon mixture by a Rhodococcus sp.
Authors: Zhang Xing , Qin Jie
Published: December 2024

Rhodococcus sp. strain p52, an aerobic dioxin degrader, was capable of utilizing petroleum hydrocarbons as the sole sources of carbon and energy for growth. In the present study, the degradation of the mixture of aliphatic hydrocarbons (hexadecane and tetradecane) and aromatic hydrocarbons (phenanthrene and anthracene) by strain p52 was examined. The results showed that the degradation of phenanthrene was enhanced in the presence of hexadecane or tetradecane due to increased bioavailability and improved cell surface hydrophobicity, which facilitated better substrate uptake. Conversely, the degradation of hexadecane and tetradecane decreased in the presence of aromatic hydrocarbons, likely due to the cometabolic effect, metabolic regulation, substrate competition, and the shift in enzyme activity. Moreover, the removal of 4.4 g L−1 diesel fuel, a complex mixture of aliphatic hydrocarbons and aromatic hydrocarbons, was investigated and 63.7% of oil contents were depleted within 96 h. Therefore, strain p52 showed the potential to remove petroleum pollutants.
Genomic Security in the Criminal Policies of the BRICS Countries
Authors: Trikoz E. , Gulyaeva E. , Brasil D. R.
Published: December 2024

This article is devoted to the legislative regulation, court practice, and criminal policy in the field of genomic security within the jurisdiction of the BRICS countries. Researchers examine China’s experience with national legal regulation on matters related to genomics, the legal practices regarding genomic security in India, and the legal experience with genetic regulation of South Africa. For the longest time, the Chinese model of legal regulation had remained in its infancy; however, the high-profile case of a biologist named He Jiankui, who genetically edited the human genome, raised ethical issues that necessitated urgent legislative settlement. As a result, amendments were introduced to the criminal and civil codes and stricter state control was established over the research activities of scientists and the licensing of clinical trials. In South Africa, for instance, tribal genomic sovereignty is protected by local laws. Nevertheless, the free circulation of genetic data is a cause for concern, licensing control by the South African government is not adequately developed, and there is a lack of sufficient knowledge and training among scientists.
Green Waste Practices as Climate Adaptation and Mitigation Actions: Grassroots Initiatives in Russia
Authors: Zakharova O. , Glazkova A.
Published: December 2024

Responding to global climate challenges, states are pursuing mitigation and climate adaptation policies, which requires involvement of all actors ranging from global institutions to the public. This article aims to evaluate green waste practices of nongovernmental organizations in terms of the possibility of incorporating these practices into climate mitigation and adaptation policies. The study focuses on two nongovernmental organizations that have been involved in waste management for more than 10 years and has examined the online posts of these organizations to determine the prevalence of nine green waste practices, as well as subscribers’ interest in them. The posts are classified using modern machine learning methods. To train a machine learning classifier, we used a dataset for detecting mentions of green practices in social media posts. The study demonstrated that environmental nongovernmental organizations engage hundreds of people in green practices aiming to reduce anthropogenic climate impacts or adapt to climate change. The often-mentioned practices (separate waste collection, recycling, and other adaptation activities such as promoting responsible consumption or refusing purchases) can be included in governmental policy. Subscribers are aware of ways to reduce consumption and manage wastes responsibly and they can share their experience with the communities gaining the support of the government. The proposed recommendations are related to broad engagement of grassroots initiatives in climate policy implementation.
National and Ethnic Identity in the Constitutions of the BRICS Countries
Authors: Gladun E.
Published: December 2024

The article presents the transformation of the concept of ethnicity, which is evident in many countries across the world in the context of changing world order. The author demonstrates the tendency to accept poly ethnicity and multiple faces in modern states, including the BRICS countries. Also, the author examines various approaches to defining ethnicity that exist both in legal science and in other social sciences. Using the example of the BRICS countries, it is shown that the legal recognition of ethnic identity, language and cultural differences occurs at the level of national constitutions since these categories are essential for recognition and awareness of each citizen and each national society in existing multinational states. The author proves that the formation of constitutional and legal norms taking into account the essence of ethnicity will contribute to the sustainable development of multinational states.
Bibliometrix applied to computational simulation for wind generator
Authors: Viana Tainan , Sales Costa Alexandre , Albuquerque Fortes Lara , Freitas de Andrade Carla , Olímpio Moura Carneiro Francisco , Moura de Oliveira Mona Lisa
Published: December 2024

This study presents a comprehensive bibliometric analysis of computational simulations in wind turbine projects, addressing their pivotal role amid growing demands for renewable energy and engineering project optimization. The primary objective is to discern trends, focal areas, and global collaboration networks.Utilizing Scopus and Web of Science databases, supported by CAPES, all pertinent publications on computational simulations in wind turbine projects were scrutinized. Bibliometric metrics were analyzed using the bibliometrix library in R.Findings reveal a increase in publications since 2022, particularly in aerodynamic optimization and offshore projects. Leading contributors are universities, research centers across Europe, North America, and prominently China. Co-authorship networks underscore significant collaborations among global academic institutions. Key terms such as "computational modeling," "CFD (Computational Fluid Dynamics)," and "wind turbine" predominate in literature.The analysis confirms the escalating significance of computational simulations in wind turbine projects, underscored by burgeoning publications and international partnerships. Integration of emerging technologies like artificial intelligence and machine learning into market practices is evident. This study serves as a foundational resource for future researchers and industry stakeholders, identifying promising avenues and areas necessitating further exploration.
A Case Report of Severe Hypothyroidism-induced Cardiomyopathy and Anemia: The Concealed Cause
Authors: Tabatabai Sadeq , Barzargani Nooshin
Published: December 2024

Background:

Cardiomyopathies are a broad range of cardiac illnesses defined by mechanical and/or electrical dysfunction and abnormal ventricular hypertrophy
or dilatation. Cardiomyopathies are classified into two categories: either primarily related to myocardial disease or secondary to other systemic or
organ disorders, including the thyroid gland. Thyroid hormones have been linked to a wide range of significant effects on the cardiovascular
system.

Case Presentation:

We experienced a case of a 37-year-old male who presented with symptoms of heart failure and was discovered to have dilated cardiomyopathy.
The echocardiography study revealed significant left ventricular global hypokinesia and severely depressed left ventricular systolic function. The
laboratory testing confirms the presence of severe normocytic, normochromic anemia with severe hypothyroidism

Conclusion:

The present case illustrates that hypothyroidism should be addressed systematically by healthcare providers when dilated cardiomyopathy is
identified, and thyroid function testing should be regularly performed.
Novel Hypoxia-related Biomarkers and Targeted Drugs for Acute
Myocardial Infarction Revealed by Bioinformatics
Authors: Xu Lei , Zeng Yuchun , Li Wenying , Zeng Xiaoquan , Zhong Guofu , Chen Junteng , Wang Ling , Xu Mujuan , Zeng Qianlong
Published: December 2024

Background:

Acute myocardial infarction (MI) is a serious emergency disease with high
mortality. Hypoxia is associated with unfavorable outcomes in cancer patients. Nevertheless, there
remains a shortage of effective hypoxia-related biomarkers to forecast the prognosis of acute MI
patients and to identify targeted therapies.

Methods:

First, data on acute MI patient samples and hypoxia-related genes were obtained based on
public databases. Hypoxia-related gene scores were calculated by single sample Gene Set Enrichment
Analysis (ssGSEA). Hypoxia-related hub genes in acute MI were screened via weighted correlation
network analysis (WGCNA). Acute MI samples were analyzed for differentially expressed
genes (DEGs) using the limma package and intersected with hub gene for hypoxia-related DEGs.
Then, machine learning methods were used to identify hypoxia-related biomarkers in acute MI. Gene
set enrichment analysis (GSEA) and immune infiltration analysis were performed on biomarkers.
Targeted drug prediction and molecular docking were conducted based on biomarkers.

Results:

The hypoxia-related gene score of the acute MI group was higher than the control group,
and 319 hypoxia-related hub genes in acute MI were acquired. A total of 7 hypoxia-related DEGs
were obtained by WGCNA and DEGs analysis. Then, 2 hypoxia-related biomarkers in acute MI,
HAUS3 and SLC2A3, were identified based on machine learning algorithms. Both HAUS3 and
SLC2A3 were enriched in the ribosome and spliceosome pathways. The expression levels of SLC2A3
and HAUS3 were correlated with immune cell infiltration. Furthermore, 8-hydroxyquinoline, perhexiline,
and sotalol were selected as the targeted drugs, which could bind to HAUS3 and SLC2A3.

Conclusion:

In short, we screened two important hypoxia-related biomarkers and three potential
target drugs based on bioinformatics techniques. This provides new ideas and potential drug targets
for early diagnosis and targeted therapy of acute MI.
Phytonanomaterials from Andrographis Species and their Applications
Authors: Soundarya V. , Baskaran L. , Karmegam N.
Published: December 2024

Andrographis (Acanthaceae) is a genus of 26 species native to India, mainly
used for the treatment of snake bites, diabetes, fever, cholera, dysentery, gonorrhea,
and malaria. Medicinal properties of Andrographis are attributed to the presence of
phytochemicals such as andrographolide, neoandrographolide, 14-deoxy-11,-
2-didehydroandrographolide, 14-deoxy andrographolide, isoandrographolide, 14-deoxy
andrographolide 19 β-Dglucoside, homoandrographolide, andrographan, andrographosterin, and stigmasterol. Nanotechnology is a technique capable of achieving a high
degree of precision in functions. By creating eco-friendly materials that can be applied
to nanomedicine, plants have mediated the synthesis and fabrication of materials in
nanotechnology. Mostly, silver nanoparticles biosynthesized using Andrographis
species showed significant pharmacological activities viz ., antimicrobial, antioxidant,
anti-inflammatory, antidiabetic, mosquito larvicidal, hepatocurative, and anticancer
activity.
Cultivation of Andrographis paniculata (Burm. f.) Nees
Authors: Johnson M. , Shivananthini B. , Preethi S. , George Vidyarani , Juliet I. Silvia
Published: December 2024

The present chapter provides different cultivation methods used to propagate
Andrographis paniculata and other factors that regulate the growth and yield of the
bioactive principles of andrographolides. The propagation of the Kalmegh is of two
types: vegetative, utilizing stem cuttings, and sexual, through seeds. Much work has
been done on the in vitro propagation of Kalmegh. The growth and quality of the plant
are affected by the following factors: plant geometry, planting density and harvesting
time, soil health, fertigation, shading level, endophytes, plant growth regulators,
weeding control techniques, different accessions of seeds, plant density, co-cultivation,
and aging. The available result revealed plots with 30 × 20 cm, cocopeat-RHA
medium, and 50 ppm magnesium composition, and integrated use of chemical
fertilizers, biofertilizers, and vermicompost treatments were optimum conditions for
better yield. Among different seed cultivars, Pranchiburi cultivars showed a good
percentage of germination and growth, and the highest andrographolide content was
recorded at 135 DAP in the flowering stage. GA3
treatment, 25% shading level, and
co-cultivation with Cajanus cajan exhibited better yield and quality of A. paniculata.
In dry storage, 1 to 3 months and 25°C temperature were recommended. Further works
in vegetative propagation may bring out alternative and rapid multiplication methods
for large-scale propagation of A. paniculata.
In vitro Production of Medicinally Potential Andrographolides from Andrographis Species
Authors: Karuppusamy S.
Published: December 2024

Andrographis L. (Acanthaceae) is a vital genus that produces the most
potential secondary metabolites, such as labdane diterpenoids called andrographolides.
Pharmaceutical requirements for andrographolides are sustained through habitat
collection and limited cultivation of Andrographis paniculata. However, in India, the
genus is represented by about 26 species distributed in the southern Peninsula, most of
which are endemic to the region. Commercial exploitation for andrographolide
extraction is met with A. paniculata alone. The low rate of seed production in this plant
and enormous variation in andrographolide content were found in the natural
population. Tissue culture techniques help us to produce commercially viable
andrographolides on a large scale. The present review analyzes the alternative sources
of andrographolides from diverse species of Andrographis. Also, the review describes
in vitro culture of callus and suspension cultures, the development of adventitious and
hairy root cultures, the addition of biotic and abiotic elicitors for enhancing
andrographolide production, and also the production of valuable compounds by
utilizing bioreactors, Agrobacterium-mediated transformation, and genetic engineering
for increasing biosynthesis of andrographolides.
Stability Property of Some Neural Firing and Avian Influenza Infection Models
Authors: Oyelami Benjamin Oyediran
Published: December 2024

The stability property of equilibrium points of some neural network models
is investigated. We have introduced different types of Lyapunov functions to carry
out the investigation. The models considered are: Grossberg, Hopfield, Fitz-Nagomo
and Fitzhugh models, respectively. The equilibrium points and stability conditions are
obtained for the Avian influenza infection. The conditions for bio economic
equilibrium points for the fish model were also obtained.
Estimación de la huella carbono de la electromovilidad en el Perú
Authors: Sanchez Agurto Yoner Alejo , Ayala Obregón Alan , Santa María Dávila Edward
Published: December 2024

El transporte es el sector de mayores emisiones de Gases de Efecto Invernadero (GEI) en el Perú, y casi completamente dependiente de los recursos energéticos fósiles. Para el presente análisis se ha tomado en cuenta la comparación de las emisiones de carbono durante la producción de electricidad, que podrá servir como base para entender la huella carbono (HC) de las alternativas que puedan derivarse por el uso de los vehículos eléctricos. A partir de los valores estimados de emisiones según tipo de fuente de generación eléctrica (renovable o térmica), se han realizado escenarios para el cálculo de emisiones bajo condición de electromovilidad. La HC del vehículo a combustión es de 180 gCO2eq/pas-km, mientras que, la HC de los vehículos eléctricos con energía renovable, electricidad nacional y electricidad fósil son 12, 89 y 140 gCO2eq/pas-km respectivamente. La reducción de emisiones de CO2 eq. con la energía eléctrica renovable es del 93%, mientras que, con la energía eléctrica térmica se logra el 22%, en ambos casos, respecto a la fuente de energía actual: la gasolina. En este artículo también trataremos de mostrar numéricamente como el uso de la energía eléctrica renovable hará del transporte más sostenible debido a la reducción considerable de emisiones de CO2.
Desarrollo de un modelo de evaluación de parámetros ambientales para lograr el confort térmico en viviendas de Kallapuma
Authors: Girón Pizarro María Lourdes , Polo Bravo Carlos Armando , Gómez León Mónica Marcela
Published: December 2024

La presente investigación se basa en el estudio del confort térmico de los pobladores del Centro Poblado Menor de Kallapuma ubicado a 4258 m.s.n.m en el distrito de Tarata, provincia y región de Tacna.
Para evaluar los parámetros ambientales se aplicaron encuestas de satisfacción teniendo en cuenta la vestimenta, alimentación, actividad física y la comodidad térmica. Así mismo se utilizó un dispositivo denominado TSVR, que permitió medir la temperatura, humedad relativa, percepciones de confort como la sensación térmica, información personal e indumentaria que utilizaba el usuario, denominado voto de sensación térmica (VST).
Estas mediciones fueron tomadas en los meses de mayo, junio y julio del año 2022.  Se analizó la aceptabilidad real que tienen los usuarios de las condiciones térmicas. Una vez obtenidos los datos, se identificó la temperatura de neutralidad y los rangos de confort térmico para la población del Centro Poblado Menor de Kallapuma teniendo en cuenta las normas ASHRAE 55 e ISO 7730 y comparándose con modelos desarrollados por autores como Fanger, Humphreys, Givoni, entre otros.
Conocer las condiciones definidas de confort térmico y el tipo de población favorecerá el diseño de viviendas en zonas altoandinas. Expresar las condiciones relacionadas a la temperatura, humedad relativa y percepciones de confort térmico facilita la aplicación de estrategias pasivas de acondicionamiento ambiental.
Evaluación del comportamiento térmico de un sistema constructivo de pared en zona altoandina utilizando un módulo experimental
Authors: Molina Fuertes Juan Omar , Horn Mutschler Manfred Josef , Gómez León Mónica Marcela
Published: December 2024

El presente artículo tiene como objetivo evaluar el comportamiento térmico de un sistema constructivo de pared de ladrillo de arcilla roja cocida con cavidades de uso masivo en las grandes ciudades del Perú, y que en estos tiempos se viene masificando en zonas altoandinas sin ser evaluados en climas de heladas. Por consiguiente, se ha llevado a cabo una construcción de un módulo experimental a escala real a 4500 msnm. La experimentación llevada a cabo durante 49 días evidencia que el retraso térmico y factor de decremento son de 4 h y 0,27, siendo el promedio horario diario de la amplitud térmica interior 6,4 °C y exterior 17,1 °C. Asimismo, del estudio numérico mediante el uso del software EnergyPlus y la implementación del modelo equivalente de conjunto de capas homogéneas para materiales heterogéneos que considera de manera dinámica los modos de transferencia de calor por conducción, convección y radiación, se logran buenas concordancias de la temperatura interior entre los valores medidos y simulados con índices de R2 de 0,87 y RMSE 0,91, lo que valida el modelo del módulo experimental.
ETHNOMATHEMATICS EXPLORATION OF GEOMETRIC TRANSFORMATION CONCEPTS IN TRADITIONAL CLOTHES OF THE DAYAK KENYAH TRIBE
Authors: Abbas Abdul Basir , Muhtadin Achmad , Jalung Krismarlina
Published: December 2024

This study aims to explore the traditional clothes of the Dayak Kenyah tribe and is related to the concept of geometric transformation. This type of research is qualitative research with an ethnographic approach. The subject of this research is the traditional clothes and accessories of the Dayak Kenyah tribe, while the object of this study is the geometric transformation concept of the Dayak Kenyah in traditional clothes motifs. Data was collected through observation, interview, and documentation in traditional clothes of the Dayak Kenyah tribe. Based on the exploration results, it was found thirteen traditional clothes and accessories for the Dayak Kenyah traditional clothes (Bluko, Besunung, Tabit, Kelempit, Baheng, Sapai, Ta'a, Tapung, Sabau, Uleng, Seleng, Kirip, and Anting) which are examples of the application geometric transformation concepts. The results of the research show that the motifs found in the traditional clothing of the Dayak Kenyah tribe can be a concrete example of the concept of geometric transformation. The geometric transformation concepts found include (1) Translation in Tabit, Kelempit, Ta'a, and Sabau; (2) Reflections in Bluko, Tabit, Kelempit, Sapai, Ta'a, Tapung, Sabau, Uleng, Seleng and Earrings; (3) Rotation of the Tabit; (4) No dilatation was found in the traditional clothes motifs of the Dayak Kenyah tribe. Apart from that, in Besunung, Baheng, and Kirip, there is no concept of geometric transformation. The example represented in the traditional clothes of the Dayak Kenyah tribe can then become an alternative recommendation for learning media so that students can better interpret geometric transformation material contextually.
Analysis of stunting handling indicators based on SSGI 2022 data in Lampung Province: Multilevel analysis
Authors: Betania Sakha Ukta , Wiboworini Budiyanti , Qadrijati Isna
Published: December 2024

Background: The implementation of specific and sensitive nutrition interventions is an effort to prevent the increasing prevalence of stunting in Indonesia. However, not all target indicators performed optimally in their implementation, which could affect the increase in stunting prevalence.

Objectives: Analyze the dominant factors of stunting incidence among toddlers aged 12-13 months from suboptimal handling of stunting in Lampung Province.

Methods: This study utilized a cross-sectional design with secondary data from the 2022 Indonesian Nutrition Status Survey. The variables in this study were iron tablet consumption, exclusive breastfeeding, growth monitoring, primary immunization, access to drinking water, access to sanitation, and the incidence of stunting, and considering heterogeneity in subdisctrict and regencies/municipalities. The subjects were 1.929 toddlers aged 12-23 months, selected by purposive sampling. Data were analyzed with a frequency distribution table, a Chi-Square test, and a multilevel binary logistic regression test.

Results: Chi-square test showed there was no relationship between iron tablet consumption (p=0.362; OR=1.14), exclusive breastfeeding (p=0.164; OR=0.85), growth monitoring (p=0.807; OR=1.08), and access to sanitation (p=0.431; OR=1.18) with incidence of stunting. However, there was a relationship between primary immunization (p=0.008; OR=1.39) and acces to drinking water (p=0.023; OR=1.35). Multilevel test results showed that there was no effect of non-exclusive breastfeeding (aOR=0,84; p>0,05) not routine growth monitoring (aOR=1,03;p>0,05), inappropriate iron tablet consumption (aOR=1,14; p>0,05), inadequate access to sanitation (aOR=1,10; p>0,05), rural domicile (aOR = 1,03; p>0,05), number of community health centers (aOR=1,00; p>0,05) contour of mountain territory (aOR=0,89; p>0,05), and contour of water territory (aOR=0,83; p>0,05) with incidence of stunting. Household-level variation had the largest effect on stunting incidence, with an ICC of 7,63%.

Conclusions: Incomplete primary immunization and inadequate access to drinking water were the dominant factors affecting stunting in toddlers aged 12-23 months in Lampung Province.
Late Middle to Late Ordovician Phosphate Accumulation of the Moyero River Section (Siberia): A Record of Upwelling and Global Cooling
Authors: Lykov Nikita , Rostovtseva Yu. , Dronov Andrey
Published: December 2024

The phosphate-bearing rocks (phosphate rocks and phosphorites) were studied over a 45-meter interval of the Moyero river section, covering the upper part of the Darriwilian and the lower part of the Sandbian stages of the Ordovician. These rocks were investigated by field observations and laboratory methods, including optic and scanning electron microscopy, X-ray diffraction analyses. The accumulation of phosphatic matter is manifested in carbonates, sandstones, and aleurolites in the form of grains (ooids and peloids), intraclasts, phosphatic and phosphatized shells. In argillites, it is represented by cryptocrystalline matter. Phosphate matter consists of fluorapatite. The peaks of phosphate accumulation are associated with the formation of layers of physically reworked granular phosphorites (condensation horizons) directly above the depositional sequence boundaries. The formation of the studied phosphate-bearing rocks during the Darriwilian-Sandbian transition was influenced by a combination of global (Great Ordovician Biodiversification Event (GOBE), reduction in sea surface temperature, atmospheric CO2, high sea level, flooding of craton margins) and regional (equatorial position of Siberia, arid climate, facies) factors. Global conditions led to the enrichment of seawater with phosphorus and the effect of upwelling. Regional conditions determined the characteristics of phosphate formation. Studied phosphate-bearing rocks can be considered as a record of upwelling on the Siberian craton during the Middle-Late Ordovician transition and one of the manifestations of long-term global cooling started early in the Middle Ordovician.