bluuebunny/crossref_metadata_2025 huggingface dataset:
Do Entendimento à Aplicação: Requisitos de Privacidade e a Visão dos Usuários sobre a LGPD
Authors: Melo Ruy Ovídio Perrelli de , Vilela Jéssyka , Silva Carla
Published: July 2024

Contexto: Casos recentes de vazamento de dados começaram a se tornar frequentes, despertando a preocupação dos usuários acerca dos seus dados pessoais. Diante disso, diversos países sancionaram leis de proteção de dados pessoais com o intuito de regulamentar como esses dados devem ser tratados pelas empresas, prevendo punições e sanções em caso de descumprimento. Problema: Diante desse cenário, surge a necessidade de compreender qual é a percepção e nível de conhecimento dos usuários sobre as leis de proteção de dados. Objetivo: Portanto, pretende-se investigar a percepção dos usuários sobre privacidade e seu nível de conhecimento sobre a Lei Geral de Proteção de Dados Pessoais (LGPD). Método: Um survey foi aplicado a usuários de sistemas e aplicativos. Resultados: Um panorama geral da percepção dos usuários, suas expectativas e conhecimentos acerca da LGPD foi obtido. Conclusão: Verificou-se a preocupação e insegurança dos usuários com os seus dados pessoais na Internet, reforçando a necessidade de criar uma cultura de privacidade.
INTERNAÇÕES PSIQUIÁTRICAS NO ESTADO DO PARANÁ: UM BREVE COMENTÁRIO LEGAL E PRÁTICO
Authors: Lucietti Filho Wlademir Junior
Published: July 2024

O presente artigo visa abordar os aspectos legais e gerais das internações psiquiátricas por saúde mental ou por dependência de álcool e drogas. Com isso, de forma analítica serão estudadas as Leis Federais nº 11.343, de 2006, e nº 10.216, de 2001, e a Lei Estadual nº 11.189, de 1995, mais precisamente sobre as definições em torno das modalidades de internamento e a origem do papel fiscalizatório do Ministério Público nesta pasta. Além disso, será demonstrada a forma de atuação do Ministério Público do Estado do Paraná na garantia dos direitos fundamentais dos pacientes internados, a fim de coibir eventuais abusos em seus tratamentos. Desse modo, será apresentada a forma de controle dos internamentos por parte do Ministério Público e algumas fraquezas legislativas que inviabilizam uma fiscalização ainda mais efetiva.
LAS ARMAS TECNOLÓGICAS: ESTUDIO DE SUS LIMITACIONES EN LOS DERECHOS HUMANOS
Authors: Rodríguez Laura Milena Tous , Calderón-Valencia Felipe
Published: July 2024

Dado al gran impacto que están teniendo las empresas en la economía global, se han buscado alternativas para regular las acciones que están afectando directamente a los derechos humanos. Estas incidencias han generado una creciente incertidumbre sobre como regular las actividades empresariales con el objetivo de mitigar las violaciones a los derechos humanos, tales como la explotación laboral y los daños ambientales. Ante esta situación, surgen los Principios Ruggie, con el objetivo de garantizar el respeto de los derechos humanos en sus operaciones empresariales ya sea de forma directa o indirecta, ante la ausencia de regulaciones de las gestiones empresariales se establecen determinados pactos y convenios. Asimismo, que el área tecnológica también se revestía de cumplir con los Principios Rectores y demás. Debido al uso excesivo de las armas cibernéticas causa incertidumbre por no tener ningún tipo de restricción y tampoco se tiene un marco normativo global para la regulación de estas armas.
DEMANDA OCULTA: RELATO DE CASO
Authors: Souza Maria Cecilia Terra de , Arantes Leandro Dalbonne , Neves Ana Carolina Batista , Lustosa Andre Luis Morelli , Silva Carlos Gabriel Paiva , Souza Gabriela dos Santos , Araujo Renato Camargo de Jesus
Published: July 2024

Demanda oculta na prática médica, refere-se a queixas que são apresentadas tardiamente ou não são apresentadas durante a consulta. Outros termos são encontrados na literatura para descrever este problema, como: Hidden agenda, by the way syndrome, doorknob syndrome (traduzindo diretamente para síndrome da maçaneta). Estes termos referem-se a um comportamento da parte dos pacientes muito visto no atendimento ambulatorial, revelando o real motivo da consulta ou outras queixas pertinentes no momento que estão deixando a sala de atendimento. As explicações para tal comportamento são complexas, envolvendo aspectos como ambiente de atendimento, ferramentas de comunicação utilizadas, relação entre os profissionais de saúde e pacientes, dentre outros. O não reconhecimento dessas demandas ocultas impacta de forma negativa o resultado do atendimento, principalmente na atenção primária. Deste modo o presente artigo tem como objetivo descrever um relato de caso com intuito de chamar atenção dos profissionais da área da saúde a respeito da demanda oculta, discorrer, com embasamento teórico referenciado, dados relevantes que ratifiquem a preocupação em identificar queixas não faladas por parte dos pacientes e realizar, com maior freqüência, diagnósticos e tratamentos corretos. Para isso, a metodologia consiste em pesquisas nas plataformas Scielo, PubMed/Medline, BVS (Biblioteca Virtual em Saúde),New England Jornal of Medicine (MEJM),com intuito de associar o caso clinico a revisão de literatura narrativa, com artigos datados a partir do ano de 1987 até o ano de 2016. Conclui-se que é necessário conhecimento por parte dos profissionais da área de saúde sobre o conceito de demanda oculta, para que haja melhor investigação diagnostica, plano terapêutico adequado, melhor adesão do paciente, e maior satisfação entre usuários e prestadores dos serviços de saúde.
DESAFIOS E CONSQUISTAS: Experiências da Enfermagem do Trabalho em um Hospital
Authors: Kenupp Suellen de Souza , Loureiro Lucrécia Helena , Santos Douglas Markonne de Souza , Balbino Carlos Marcelo
Published: July 2024

Trata-se de um relato de experiência de uma enfermeira do trabalho sobre o cotidiano vivenciado durante práticas assistências e gerenciais de cuidado em saúde ocupacional, ao longo dos anos em um hospital privado que atende pacientes do Sistema Único de Saúde (SUS) situado na região Sul Fluminense do Rio de Janeiro. Tem como objetivo principal relatar as práticas cuidativas realizadas pela profissional no nosocômio, que estão relacionadas a atividades de rotinas burocráticas e de cuidado; educação permanente com profissionais da enfermagem, da saúde e da administração a fim de contribuir com a ampliação de conhecimentos e mudanças de atitudes salutares às boas práticas estabelecidas pela legislação em segurança e saúde ocupacional brasileira. Menciona-se que há oportunidades para atuar em campanhas de vacinação, promoção da saúde e prevenção de doenças ocupacionais e profissionais, treinamentos e palestras educativas. Observa-se que a equipe de enfermagem exerce períodos ininterruptos de atividades, que apresentam sobrecarga de trabalho; ocasionando o adoecimento e as ausências evitáveis dos profissionais. Fato relatado em conversas informais sobre o cansaço físico e mental durante as longas horas de jornada trabalhadas, o cansaço excessivo, o ganho de peso, a falta de paciência, o esgotamento físico e mental, a falta de tempos com a família, preocupações com os filhos e da necessidade de preservar outros vínculos de trabalho para manter as finanças familiares. Conclui-se que a atuação da enfermagem do trabalho no ambiente hospitalar contribui para saúde integral dos profissionais atendidos pelo setor de medicina ocupacional, de maneira a prevenir e acompanhar ambulatoriamente os funcionários. Assim, colabora para a diminuição das ocorrências de absentismo ao promover a gestão em enfermagem, organizando e planejando as escalas dos trabalhadores necessárias para a completude dos afazeres assistenciais e gerenciais do hospital.
O IMPACTO DO USO DOS FLORAIS DE BACH E BUSH AUSTRALIANO NO TRATAMENTO DE UMA CRIANÇA AUTISTA
Authors: Santos Ana Cristina Tavares Silveira , Oliveira Priscila Tavares Nascimento de , Souto Rosana
Published: July 2024

O artigo aborda o uso da terapia floral, especialmente os sistemas Bach e Bush Australiano, no tratamento complementar de crianças no espectro autista. Explora-se a história e os fundamentos da terapia floral, destacando os remédios desenvolvidos pelo Dr. Edward Bach e Ian White. O estudo detalha os sintomas e diagnóstico do transtorno do espectro autista (TEA) e a crescente prevalência desse transtorno. Apresenta-se um estudo de caso envolvendo uma criança com TEA, que recebeu tratamento com florais de Bach e Australianos, evidenciando melhorias significativas em sua comunicação, comportamento, sono e interação social, entre outros aspectos. Além disso, são mencionados estudos científicos que apontam a eficácia da terapia floral em diversas condições, como ansiedade e síndrome do túnel do carpo. O artigo conclui ressaltando o potencial terapêutico dos florais na prática clínica, especialmente em crianças autistas, embora mais pesquisas sejam necessárias para confirmar esses resultados.
Improvement of the Cognitive Abilities in a Chronic Generalized Anxiety Disorder and Moderate Depression Case using a Novel Integrated Approach: The Cognitome Program
Authors: Mohita Shrivastava
Published: July 2024

Cognitive impairment has been increasingly observed among patients with anxiety disorders and major depressive disorders impacting their normal daily functioning as well as quality of life. A multitude of evidence suggests that the most affected cognitive abilities are memory, attention, perception, and executive functioning in patients with anxiety and depression. Impairment in these higher-order cognitive functions can be attributed to age, education, diet, hormonal changes, stress, and prolonged use of drugs/alcohol/ medicines. To address the issues related to cognitive impairment various non-pharmacological therapeutic modalities such as Cognitive remediation approaches viz; cognitive rehabilitation, cognitive stimulation, and cognitive training; Audio-visual entrainment; mindfulness-based interventions; and neurofeedback have come into play in recent years. It is imperative to understand that the ability to test, measure, and monitor cognitive performance along with implementing cognitive remediation approaches viz; cognitive stimulation, cognitive training, etc. across the lifespan helps in early identification, accessing treatments faster, staying healthy for longer, and improving overall quality of life. This article discusses a case study of a client suffering from generalized anxiety disorder and moderate depression who after undergoing and following a novel therapeutic approach, ‘The Cognitome Program’ has shown credible improvement in cognitive abilities, along with a prominent reduction in the symptoms of anxiety, depression, and better psychological and physical well-being. Guided by the concept of neuroplasticity and cognitive plasticity, our innovative neuroscientific holistic program- ‘The Cognitome Program’ empowers unlocking hidden cognitive potential using cutting-edge methodologies and personalized strategies.
Genetic Variability and Antibacterial Sensitivity of Dichelobacter nodosus and Fusobacterium necrophorum Infection in Sheep Sulaimani Province, Kurdistan Region, Iraq
Authors: Sulaiman Rizgar Rahim , Marif Hardi Fattah , Ali Basim Abdulwahid , Ali Kwestan Najm , Baba Shekh Muhamad Omer
Published: July 2024

Footrot is a significant health problem in ruminants, especially sheep, caused by the bacteria Dichelobacter nodosus and Fusobacterium necrophorum. Infected animals may become lame and lose body condition. The aim of this study was to investigate whether sheep had mixed infections with D. nodosus and F. necrophorum, the global genetic relationships of both target genes (lktA and 16S rRNA genes) with different reference genes, and the degree of genetic heterogeneity between the standard serogroups of D. nodosus were studied. In addition, to detect the antibacterial sensitivity against these two pathogens. One hundred and seventy-five sheep interdigital spaces were investigated (2016-2022). The D. nodosus field isolate (Dn Sul/016-KY399851) showed 96% compatibility with other global isolates (NR_104942/USA, JN008724/India, and DQ016290/Sweden) when its 16S rRNA sequence was compared to some reference genes. The local isolate (Fn Sul/016- KY399852) and other IktA gene strains from other nations (FJ230831/New Zealand, JX678872/Australia, JX648295/India) were compared, and the results showed 99% and 96% identity. Additionally, within the multiple sequence alignment, a single nucleotide variation at position 389 (CA) was seen in the partial lktA sequence when compared to the field isolate (Fn Sul/16-KY399852). This modification corresponds to a switch at residue 130 from alanine (Ala) to glutamic acid (Glu). This study showed the initial molecular identification of D. nodosus and F. necrophorum from sheep with footrot in the Iraqi province of Sulaimani‎‎‎‎‎.
Language choices and distributions in informal public space: A case in Winneba
Authors: Hamidu Alhassan  , Isaac Oduro  , Godwin Kusi Danquah  , Patience Addo-Kuffuor  , Yaa Asantewaa Bediako  , Veronica Wiafe
Published: July 2024

This paper investigates the influence of linguistic variables on language choices and distributions in Informal Public Space in Winneba. The aim of the study is to bring to light the linguistic choices that are made in Winneba where existing studies have described as multilingual setting. Demographically, the study divided Winneba into Formal Public Space, Informal Public Space and Semi-Formal Public Space. The focus of the study was on the informal public space defined in the study as places such as lorry stations, market places, saloons, dressmaking centers, shops, drug stores, drinking bars, food joints, restaurants, hawkers, hostels, etc. The study is grounded in qualitative approach and rooted in survey as design. In terms of sampling, the study randomly sampled and administered questionnaires to two hundred and fifty (250) respondents operating in twelfth (12) domains which constitute the Informal Public Space in Winneba. From the study, it emerged that, the university community now determines language distribution in the informal public space in Winneba. This new trend has given the English Language the urge to spread from the formal public space across all the other spaces leading to a diglossia. The effect of this new linguistic trend in Winneba is the competition between English language and Fante (Effutu/Guan) for dominance in the Informal Public Space which is highly dominated by non-literates. This competition has led to usurpation of spaces by the two dominant languages with the overall effect being the weaken language; Efutu which faces possible extinction in the near future.
Detection of synthetic pesticide residues prevalent in daily consuming salad vegetables sold in the local markets of Rajshahi City, Bangladesh
Authors: Ismat Moin Tamanna  , Md. Badrul Islam  , G.M Masud Rana  , Sarmina Yeasmin  , Tahmina Akter Chowdhury
Published: July 2024

Fresh salad vegetables have become a convenient part of daily diet of people nowadays because of their nutritional enrichment. Although raw vegetables are compact source of high nutritional values, these vegetables are sometimes detrimental to human health because of being potential route of human exposure to pesticide contaminants. This study is focused on the prevalence of pesticide contaminants in daily consuming common salad vegetables. The study was conducted to observe six pesticides residue (Cypermethrin, Mancozeb, Malathion, Rovral, Imazalil, Endrin) using gas chromatography mass spectrometry (GC-MS) in five types of raw consuming vegetables that are sold in the local markets of Rajshahi City. The findings suggest that almost all the vegetables of three markets were contamination free. The residual level of all six targeted pesticides had not been detected. Thus, this study suggests that the application of pesticides in the fields of Rajshahi City is within safe limit.
Exploring the relationship between strategic planning and employee performance: case study of Taleemabad, a Startup Located in Islamabad
Authors: Luqman Ali Awan  , Bambang Purwanggono  , Wiwik Budiawan
Published: July 2024

This study delved into strategic planning practices and their connection with an institution’s context and performance. It aimed to establish the link between strategic management and an organization’s success, emphasizing that effective strategic management significantly influences performance. Successful companies worldwide exhibit well-defined strategies and step-by-step goal setting, contributing to their achievements on local and global scales. This paper highlights the central concern of strategic management in understanding performance disparities among competing organizations. The research outcomes hold significance not only for scholars of strategic management but also for practicing managers seeking competitiveness through strategic planning. The study aids managers in recognizing obstacles in strategic decision-making and offers insights into the impact of strategic planning on organizational performance. As there is a dearth of research in this area, the paper proposes avenues for future research grounded in empirical evidence. This research enriches the understanding of the critical relationship between strategic planning, institutional context, and organizational success.
Analisis Mengenai Studi Kelayakan Usaha Ecoblock Dalam Rangka Daur Ulang Sampah Plastik Di Salatiga
Authors: Karunianto Mu'amar Andi , Tejanagara Orlando Samuel , Napitupulu Obi Sepanya , Martono Samuel
Published: July 2024

Sampah telah menjadi permasalahan utama dunia terlebih jika dikaitkan dengan keberlangsungan hidup manusia. Sampah yang tidak dikelola dengan baik akan membuat pencemaran di lingkungan sekitar, untuk mencegah hal tersebut pemerintah menerapkan program 3R (Reduce, Reuse, dan Recycle). Adanya permasalahan tersebut membuat sebuah peluang bisnis yang dapat membuat sampah plastik menjadi sebuah produk dengan nilai jual. Studi kelayakan usaha ini berfokus dalam menganalisis sebuah proyek yang nantinya dapat dilakukan oleh mitra seperti Pemerintah Daerah ataupun investor seperti sebuah perusahaan. Proyek ecoblock merupakan salah satu upaya masyarakat melalui program Reuse dan Recycle dalam mengurangi sampah terutama sampah plastik yang diubah menjadi barang dengan nilai guna sehingga mampu bermanfaat secara ekonomi dan sosial yang akan dilakukan di daerah TPA Ngronggo Salatiga. Periode dilakukannya penelitian dari 29 Agustus 2023 hingga 11 Desember 2023 yang merupakan jenis penelitian (field research) dengan metode kualitatif.  Teknik analisis dalam studi kelayakan usaha proyek ecoblock berdasarkan beberapa aspek yaitu aspek pasar, aspek teknis, aspek manajemen, aspek hukum, dan aspek finansial. Melalui penilaian yang telah dilakukan dapat disimpulkan dari kelima aspek analisis bahwa proyek ecoblock dapat dikatakan layak sehingga investor ataupun mitra yang ingin melaksanakan proyek ecoblock dapat dilaksanakan.
Multilingual Literacy and Metalinguistic Reflection in Primary School
Authors: Atz Emanuela , Varcasia Cecilia
Published: July 2024

This paper addresses the issue of multilingual classrooms in a context such as South Tyrol (Italy), characterized by both endogenous and exogenous multilingualism, the latter stemming from pupils with international backgrounds. The paper discusses the results of a research study conducted in highly multilingual primary school classrooms, inspired by the concept of ‘Éveil aux langues’, with the goal of fostering metalinguistic awareness.
BİRİNCİ DÜNYA HARBİ ÖNCESİ BÜYÜK DEVLETLERİN TAKİP ETTİĞİ AKDENİZ SİYASETİNİN DEMİRYOLU İMTİYAZI VE PETROL AÇISINDAN DEĞERLENDİRİLMESİ
Authors: Güvenbaş Sehernaz
Published: July 2024

Üç kıtayı birbirine bağlayan Akdeniz, tarih boyunca buraya hâkim olmak isteyen devletlerin ilgisini çekmiş ve devletler bu uğurda savaşmaktan da geri durmamıştır. Akdeniz hâkimiyet mücadelesi bölgedeki ticaret yollarına sahip olup ekonomiye hükmetme düşüncesiyle başlamışken bu mücadele Birinci Dünya Harbi öncesi bölgedeki kaynakların elde edilmesi politikasına dönüşmüştür.19. Yüzyıl sonları ile 20. Yüzyıl başlarında, Osmanlı Devleti sınırları içinde bilinen en mühim petrol yataklarının tespit edilmesi, endüstrileşmiş ülkeler arasındaki enerji rekabetinde bu ülkelerin dikkatlerini Mezopotamya bölgesine yoğunlaştırmalarına sebep olmuştur. Ticari ve iktisadi imtiyazlar alarak stratejik noktaları elde etmek ve demiryolu yatırımlarıyla bu kaynaklara ulaşmak, bu rekabetin temel dinamiği olmuştur. Jeopolitik ve jeostratejik öneminden dolayı günümüzde de Akdeniz’e komşu devletler ile büyük devletlerin ilgisini kaybetmeyen bu coğrafya, mevcut konumu ve enerji potansiyeli ile mücadele alanı olmaya gebe bir bölge olduğu açıkça görülmektedir. Bu çalışmada Birinci Dünya Harbi öncesinde büyük devletlerin yürütmüş olduğu siyaset ve mücadele, literatürden tespit edilen ve Osmanlı Türkçesi kaynaklarla karşılaştırmalı olarak analiz edilmeye çalışılmıştır.
Analysis of performance verbs on achievement standard in number and operations area of revised elementary mathematics curriculum from 2007 to 2022
Authors: Lee Jong Hak ,   The Korean School Mathematics Society
Published: July 2024

Based on Bloom's new educational goal classification system, the performative verbs included in the achievement standard of the revised elementary mathematics curriculum were classified by subject and analyzed longitudinally. The results are as follows. First, total number of performative verbs(262) was greater than the total number of achievement standard(210). Second, the cognitive process dimension that appeared throughout the number and operations areas was in the following order: understand, apply, remember, invent, and analyze. Third, In the entire number and operations areas, the ‘evaluate’ topic did not exist, and the ratio of the ‘analyze’ and ‘invent’ topics was not large. From the results above, it is necessary to state performative verbs in the definitional area as functions, and suggest analysis of performative verbs in other reas such as geometry and meas- urement, change and relationship, data and possibility as follow-up research.
Formation of students' knowledge about legal and moral values in the activities of Interior Ministry employees in the process of role-playing
Authors: Kutenkova Oksana Yurievna
Published: July 2024

The purpose of the work is to substantiate the importance of the introduction of role–playing games into the learning process in educational institutions of higher education of the Ministry of Internal Affairs of Russia in order to focus on the formation and development of traditional Russian spiritual and moral values. The article actualizes the importance of role-playing as an interactive form of education for the formation of professional and moral knowledge of future employees of internal affairs bodies. The scientific novelty of the research lies in the development of a role-playing game scenario, which provides for in-depth consideration not only of the provisions of normative legal acts containing requirements for the official behavior of an internal affairs officer, but also discussion of issues related to the personal moral choice of certain legal and moral values based on the principles of police activity. The role-playing game was tested by students of the St. Petersburg University of the Ministry of Internal Affairs of Russia of the 1st year of the 1st semester of the 2023-2024 academic year in the specialty 40.05.02 Law Enforcement (specialty level): cadets of 6 platoons in the number of 162 people aged 16 to 19 years. As a result of the study, the variability of interpretations of the concept of "game" is presented. An example of the application of the developed role-playing game in the educational process as an interactive teaching method that contributes to the formation of cadets' knowledge about legal and moral values in the activities of police officers is given.
Features of representation of the genre tradition of the Bildungsroman in the Russian prose of the late 1920s
Authors: Osmukhina Olga Yurievna , Ovsyannihova Ekaterina Pavlovna
Published: July 2024

The article analyzes the novellas “Kostya Ryabtsev’s Diary” by N. Ognev and “School” by A. Gaidar, which, on the one hand, continue the Bildungsroman tradition in Russian prose and, on the other hand, anticipate the birth of socialist realist literature. The aim of the study is to identify the features of the embodiment of the Bildungsroman genre tradition in these novellas. The study is original in that it is the first to analyze the phase of the socialist realist proto-canon in the context of the problem of the novel of personality formation based on the works of A. Gaidar and N. Ognev, which allows us not only to expand the scientific understanding of the artistic distinctness of socialist realism and its chronological boundaries, but also to comprehend the specifics of the refraction of the Bildungsroman tradition in them. As a result, it was found, firstly, that the genre tradition of the Bildungsroman, represented in these texts, embodies the general universal idea of the socialist realist novel – the education of workers in the spirit of socialist realism. Secondly, the markers of socialist realist consciousness, carried by the main characters, are: a clearly formed position in relation to the bourgeois class, a heightened sense of justice. Thirdly, A. Gaidar’s and N. Ognev’s protagonists have not yet come to an exclusive “positivity”: the process of transformation of Kostya Ryabtsev and Boris Gorikov is identical – it is a path from spontaneity to conscious obedience to the party. Finally, unlike that of the heroes of socialist realism, the personal development trajectory of A. Gaidar’s and N. Ognev’s heroes is a downward movement, down to the point of symbolic death.
Non-clinical Studies of Radiopharmaceuticals: Analysis of National and International Regulatory Practice (Review)
Authors: Klementyeva O. E. , Smirnova A. V. , Kulbachevskaya N. Yu. , Grigorieva E. Yu. , Lagodzinskaya Yu. S. , Gevorkyan T. G.
Published: July 2024

INTRODUCTION. Currently in the Russian Federation and the Eurasian Economic Union (EAEU), the conduct of non-clinical studies of radiopharmaceuticals is regulated by general guidelines on non-clinical studies, which are applicable to multiple groups of medicinal products but do not accommodate the characteristics of radiopharmaceuticals.

AIM. The study aimed to substantiate the need for methodological guidelines regulating non-clinical studies of radiopharmaceuticals, taking into account global regulatory practice.

DISCUSSION. The authors analysed the Russian and EAEU guidelines regulating non-clinical studies in general as well as international publications on non-clinical studies of radiopharmaceuticals, including guidelines by the US Food and Drug Administration (FDA), the European Medicines Agency (EMA), and the International Atomic Energy Agency (IAEA). The analysis revealed the need for terminology harmonisation. This article describes the aspects specific to radiopharmaceuticals that limit the applicability of general guidelines to non-clinical studies of radiopharmaceuticals. Subchronic toxicity studies based on inactive formulations do not account for the contribution of radionuclide emission to the biological effects of therapeutic radiopharmaceuticals. The authors suggest that systemic toxicity studies of finished dosage forms should use single-dose chronic toxicity protocols.

CONCLUSIONS. It is necessary to develop and implement up-to-date methodological guidelines for conducting non-clinical studies of radiopharmaceuticals to reduce potential risks in the application of these medicinal products. This requires factoring in different requirements for diagnostic and therapeutic radiopharmaceuticals, with due consideration of radiation safety requirements. When drafting guidelines for non-clinical studies of radiopharmaceuticals, regulators should keep in mind the applicable guidelines by the FDA, EMA, and IAEA. A list of mandatory studies should be compiled, and uninformative studies should be excluded from the requirements for radiopharmaceuticals.
Bacell-M® probiotic effect on genes expression level in Cobb 500 broiler cross at the phone of vaccination against infectious bronchitis
Authors: Krutov Ilya O. ,   FSBI “All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy” (FSBI ARRVIPP&T), Voronezh, Russia, Golubtsov Andrey V. , Strelnikov Nikolai A. , Marmurova Oksana M. , Yerina Tatyana A. , Mikhailov Yevgeny V. , Pasko Nadezhda V. ,   FSBI “All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy” (FSBI ARRVIPP&T), Voronezh, Russia,   FSBI “All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy” (FSBI ARRVIPP&T), Voronezh, Russia,   FSBEI HE “Voronezh State Agrarian University named after Emperor Peter I” (FSBEI HE “VSAU named after Emperor Peter I”), Voronezh, Russia,   LLC “Feed Technologies”, Voronezh, Russia,   FSBI “All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy” (FSBI ARRVIPP&T), Voronezh, Russia
Published: July 2024

The results of poultry gene expression study have been given in the paper. The study has detected maximum IL-2, IL-8 and ТNF-α genes expression level increasing in broilers with Bacell-M® ration addition 50 g per 10 kg of feed during 30 days and being vaccinated against chicken infectious bronchitis at 14th and 28th days of life with live vaccine H-120 strain in comparison with broilers without the probiotic. The fact shows immune system activation and gene quantities being produced in organism. The authors think the genes expression level study may be the method of immune system control in poultry.
Broiler slaughtering products biological value when usage in diet domestic feed additive
Authors: Kochish Ivan I. ,   FSBEI HE “Moscow State Academy of Veterinary Medicine and Biotechnology — MVA named after K.I. Skryabin” (FSBEI HE MSAVM), Moscow, Russia, Trishina Yulia V. , Petrova Yulia V. , Kalmyk Anastasii I. ,   FSBEI HE “Moscow State Academy of Veterinary Medicine and Biotechnology — MVA named after K.I. Skryabin” (FSBEI HE MSAVM), Moscow, Russia,   FSBEI HE “Moscow State Academy of Veterinary Medicine and Biotechnology — MVA named after K.I. Skryabin” (FSBEI HE MSAVM), Moscow, Russia,   FSBEI HE “Moscow State Academy of Veterinary Medicine and Biotechnology — MVA named after K.I. Skryabin” (FSBEI HE MSAVM), Moscow, Russia
Published: July 2024

The investigation has been devoted to biologic value study of broiler slaughtering products when using feed in their diet additive containing bentonite and microelements. This additive has been noted to influence positively on broiler immune status and nutrition digestion, and these promotes more intensive poultry growth and products biological value improvement.
A comparative study of deep learning techniques in software fault prediction
Authors: Phuong Ha Thi Minh , Ngan Dang Thi Kim , Binh Nguyen Thanh
Published: July 2024

Software fault prediction (SFP) is an important approach in software engineering that ensures software quality and reliability. Prediction of software faults helps developers identify faulty components in software systems. Several studies focus on software metrics which are input into machine learning models to predict faulty components. However, such studies may not capture the semantic and structural information of software that is necessary for building fault prediction models with better performance. Therefore, this paper discusses the effectiveness of deep learning models including Deep Belief Networks (DBN), Convolutional Neural Networks (CNN), Recurrent Neural Networks (RNN), and Long-Short Term Memory (LSTM) that are utilized to construct fault prediction models based on the contextual information. The experiment, which has been conducted on seven Apache datasets, with Precision, Recall, and F1-score are performance metrics. The comparison results show that LSTM and RNN are potential techniques for building highly accurate fault prediction models.
Empathy for animals: ecological ethics in Vietnamese contemporary prose
Authors: Nguyet Tran Thi Anh , Hanh Bui Bich
Published: July 2024

In response to the global environmental crisis, ecocriticism emerged in the 1970s, fitting the demands of the time and becoming a dynamic movement that continues to this day. Ecological theory acknowledges the equal existence of creatures, believing that all creatures are the same and that no species is dominating. From the innovative idea of ecocriticism, Vietnamese fictional prose after the Innovation 1986 years has emerged characters who share the sense of pain with all creatures. This article highlights the shift in environmental discourses, which no longer view humans as the lord of all creatures but rather as being able to listen to the voices of nature, care for injured animals, and love and protect all living things-a perspective that first established ecological ethics in Vietnamese literature.
A Study on the Research Trends in Achievement Standards-based Assessment Using Text Mining
Authors: Jang Eunah , Chung Hyewon ,   Korean Society for Educational Evaluation
Published: July 2024

This study aims to examine the research trends related to achievement standards-based assessment. To this end, a total of 87 papers published in KCI-listed academic journals from 2011, when the ‘Advanced Plans for Academic Administration in Secondary Schools’ was announced, to March 2024 were analyzed through keyword frequency analysis, co-occurrence analysis, LDA topic modeling, and semantic network analysis. The main findings are as follows. First, research on achievement standards-based assessment revolved around three main topics: ‘Teaching and learning design (Topic 1)’, ‘Development of achievement standards and teacher perception (Topic 2)’, and ‘Introduction of High school credit systems (Topic 3)’. Second, Topic 2 showed a decrease in research proportion, while Topic 3 showed an increase. Third, topics in achievement standards-based assessment research were found to be interconnected around ‘Curriculum’ and ‘School’. Fourth, keywords such as ‘learning’, ‘curriculum’, ‘class’ in Topic 1; ‘development’, ‘operation’, ‘school’ in Topic 2; ‘operation’, ‘high school credit system’, ‘curriculum’ in Topic 3 were identified as top keywords in terms of both degree centrality and betweenness centrality. Based on the analysis results, implications for future research directions on achievement standards-based assessment systems were suggested.
Arturo Ardao el filósofo historiador de las ideas: Pensamiento y Obra
Authors: Ramirez Rafael Félix Mora , Gastañaduy Carola Claudia Calvo , Huamán Beto Puma , Sevillano Víctor Fredy Rodríguez , Rivera Herbert Víctor Huaranga
Published: July 2024

Siempre que aparece un libro sobre el pensamiento de algún filósofo latinoamericano hay que agradecer de todo corazón a los que se esfuerzan por mantener aún vigente este tipo de producciones. Pensar nuestra región, empezando por el propio país para luego extrapolar las ideas hacia un concepto continental denominado “Latinoamérica” es una actividad a la que se dedicó el propio Arturo Ardao, filósofo que constituye el tema principal de este libro.La búsqueda del “ser latinoamericano” fue un problema que preocupó a Ardao y es un tema que hasta la fecha provoca reflexiones y pensamientos de variada índole. No obstante, el aporte de Ardao se basó en considerar que el término “Latinoamérica” tuvo motivaciones políticas integracionistas desde sus orígenes. Es más, su contenido genético semántico estuvo cargado de una clara oposición a la imposición de intereses coloniales extranjeros. Normalmente, cualquiera pensaría que dicho término es descriptivo, sin embargo, Ardao nos mostró que el origen de tal vocablo está ligado a una definición persuasiva que, a pesar de la enorme variedad de pueblos que viven en esta parte del mundo, buscaba unificar y reunir bajo una sola voluntad la lucha contra ciertos intereses imperialistas.Según Ardao, es importante considerar el contexto cuando se trata de entender cómo las filosofías logran instalarse en distintos lugares a pesar de no ser originarias de esos entornos. Ardao fue consciente de esto, por eso, para este pensador la posibilidad de que exista una filosofía latinoamericana propia se manifiesta en el hecho de que podemos estar a favor o en contra, mediante razones y propuestas, de tales o cuales ideas filosóficas. Precisamente, esa fue la tónica de aquella obra de nuestro pensador en la que analizó el modo en que se manifestaron las corrientes del Espiritualismo y del Positivismo en América Latina. Resulta interesante constatar que, en realidad, dicha oposición proviene de un debate muy propio de las academias y universidades europeas que, en pleno siglo XIX, discutían en torno a la naturaleza del conocimiento y el papel de la religión y la ciencia en la sociedad.
“I got all sorts of solitude, but that solitude wasn’t mine”: A Mixed-Methods Approach to Understanding Aloneness during Becoming A Mother
Authors: Nguyen Thuy-vy Thi , Konu Delali , Tetteh Deborah , Tshimbalanga Pearl , Weissová Julie , Xiong Mingyao
Published: July 2024

This research examined the nuanced experiences of "aloneness" among British first-time mothers, highlighting the impact of motherhood on new mothers’ solitude. Utilizing a mixed-method approach, for Study 1 we conducted qualitative interviews to explore mothers' perceptions and experiences of solitude and loneliness after becoming a mother. Study 2 tracked daily activities and emotional states through ecological momentary assessments to identify activity predictors of mothers’ daily emotional and psychological well-being. The findings indicate that motherhood significantly reduces opportunities for personal time due to constant childcare demands; however, Study 2 showed that personal time contributed positively to mothers’ daily mood. Interestingly, personal time does not require separation from the baby; such time overlaps with time for rest and relaxation, time for media-related activities, and quality time with the baby. As such, the study underscores the importance of supporting first-time mothers in finding quality personal time to mitigate the challenges of new parenthood.
Early Numeracy Development as a Foundation of Mathematics Achievement in Primary Education
Authors: Dierkx Veronique , van de Rijt Bernadette , Hessen Dave , van Luit Hans , van Viersen Sietske
Published: July 2024

Purpose: This study aimed to investigate the 1) development of early numeracy (EN) between Kindergarten and Grade 1, 2) parental factors influencing this development, and 3) its predictive value for mathematics achievement mid-primary school. Method: The sample included 1252 children whose EN was measured bi-annually across six time points. Results: Latent growth curve modeling revealed non-linear growth in EN, with stronger effects of time throughout Kindergarten and a flattening curve in Grade 1, without reaching ceiling. Lower maternal education level and migration background were associated with lower EN at baseline, but these children also show greater improvement over time. Higher baseline EN and growth positively predict mathematics achievement in mid-primary school. Conclusions: Findings confirm significant EN development throughout early grades, but learning gains are not optimal in the current informal setting. Implications for early screening and intervention to address insufficient foundational skills, essential for later mathematics achievement, are addressed.
Lifetime stressor exposure and suicidality in autistic adults: a multinational study examining the role of gender in interpersonal life stress
Authors: Moseley Rachel , Hedley Darren , Gamble-Turner Julie , Uljarevic Mirko , Bury Simon , Shields Grant , Trollor Julian N , Stokes Mark Andrew , Slavich George M.
Published: July 2024

Despite very high rates of suicidality in autistic adults, the key psychosocial drivers of this phenomenon remain unknown. To investigate this, we examined how lifetime stressor exposure and severity, which have been found to predict suicidality in non-autistic populations, related to suicidality in a large, multinational dataset of 226 autistic adults (67% female; Mage = 41.8, SD = 13.6 years, age range = 19–73). Results revealed that autistic men and women differ with respect to the count, severity, and type of stressors they experience over the life course. While autistic men were exposed to more numerous legal/crime-related stressors, autistic women experienced more numerous stressors related to social relationships and chronic humiliation, and typically experienced stressors as more severe. Additionally, we found that whereas chronic interpersonal loss was particularly strongly related to suicidality for men, acute dangerous events, and lower exposure to chronic entrapment, were most strongly related to suicidality in autistic women. These findings indicate that certain stressors may be differentially experienced, and relevant to suicidality, in autistic men versus women. They also suggest that screening for lifetime stressor exposure may help identify autistic individuals at greatest risk for suicide.
Building quantitative skills with a simplified physical model of coastal storm deposition
Authors: Lazarus Eli
Published: July 2024

This article describes an exercise for a physical laboratory experiment designed to enable physical geography students to practice transferrable quantitative skills through inquiry-based learning. The exercise is a deliberately simplified physical model of storm-driven coastal overwash typical of low-lying coastal barrier systems. The experiment can be trialled in anything from a baking pan or plastic tub to a specialised flume; set-up requires an erodible barrier with a low height relative to its alongshore length. Flow across the barrier is called overwash, which leaves behind depositional features called washover. Students measure geometric characteristics, or morphometry, of the experimental washover and examine them with scaling relationships. Here I present a dataset of nearly 450 student measurements, along with a sample of my own, from six experimental trials to demonstrate that students with little or no preparatory training were able to successfully complete the exercise and collectively generate a dataset of washover morphometry that resembles scaling relationships from the published literature. Using inquiry-based observations of a physical process to steer morphometric measurements that in turn motivate methods for quantitative analysis may serve as an effective means of embedding quantitative training in a physical geography syllabus or programme curriculum.
A cognitive signature of metabolic health in effort-based decision-making
Authors: Mehrhof Sara Z. , Fleming Hugo Alexander , Nord Camilla
Published: July 2024

Survival necessitates a delicate balance between expending effort to obtain resources, and energy conservation. Individual differences in motivation, the tendency to expend effort, play a fundamental role in society, affecting health, education, and economic outcomes. Previous theories explain variations in motivation via dopaminergic function. However, insulin resistance could also alter motivated behaviour by shifting the balance toward energy conservation. In a preregistered experiment, we investigated whether blunted motivational tendency—reduced tendency to exert effort, quantified using economic decision-making models, and previously linked to neuropsychiatric symptoms— is present in type-2 diabetes. We found subjects with type-2 diabetes showed this cognitive signature of blunted motivational tendency, compared to matched non-diabetic controls. Across a large sample with and without diabetes, we found that increasing risk for diabetes linearly predicted blunted motivational tendency. Diabetic patients treated with semaglutide did not show restored motivational tendency. Metabolic ill-health is associated with a shift towards energy conservation, potentially contributing to comorbidity between metabolic disease and mental illness.
The licensing effect in gambling choice: A daily diary study
Authors: Wu Raymond , Clark Luke
Published: July 2024

People with gambling problems gamble despite resolutions to stop. These choices may be more likely in contexts that allow for them to be justified (e.g., after a productive day at work), termed the licensing effect. This has not been tested in the domain of gambling. Using a daily diary design across 21 days (n participants = 156, n reports = 2,516), gamblers trying to reduce their gambling reported their daily justification opportunities (e.g., feelings of effort and achievement) and whether they gambled, as well as daily aspects of self-control (i.e., craving, conflict, suppression) and affect (positive and negative). Gambling occurred on 33% of the reported days. Prior-day justification opportunities were associated with a higher likelihood of gambling. Prior-day suppression showed a similar effect, whereas prior-day negative affect showed the opposite effect. After gambling, people experienced stronger cravings, weaker suppression, and poorer well-being (lower positive affect and higher negative affect). Our findings show that people may use justifications to gamble, despite its negative consequences, indicating that the licensing effect may, in part, explain why people gamble despite resolutions to stop.
Social Utility Modeling: A Tool to Gain Insight into Social Motives
Authors: Galvan Elijah Paul , Sanfey Alan
Published: July 2024

Computational modeling is an emerging analysis technique with the potential to offer important insight into how researchers in the cognitive sciences approach important questions – particularly questions about how people make choices. However, for those researchers who are interested in utilizing computational models in their own research, learning the how’s and why’s of the approach can seem prohibitively difficult. In the current work, we address these concerns by, firstly, outlining the basic principles of computational modeling in plain and accessible language. We then propose criteria to consider when adopting a computational model to answer a research question, demonstrating that Social Utility Models have many applications in the field of social cognition and enjoy useful advantages over conventional analysis approaches. Finally, in a step-by-step tutorial, we explain how to implement a computational modeling analysis and demonstrate this approach by using an example dataset.
Internationalization of Higher Education. A comparative perspective on support for international students in the United States of America, Republic of Korea, and Germany
Authors: Park Eun Young
Published: July 2024

In the process of the internationalization of higher education, a meaningful integration of international students at host universities has gained interest in the past two decades. Against this background, the purpose of this study was to explore the voices of the main actors involved, i.e., staff members, who provide social and cultural support services at host universities, and international students who experience the offered support. Three countries were selected: the United States of America (USA), the Republic of Korea (Korea), and Germany. Among these Korea was not only chosen due to the researcher’s biographical background but also recognizing the fact that Korea is the major sender of international students, and the USA and Germany are the main receivers of these students worldwide. The qualitative empirical approach chosen in this study centered around semi-structured interviews with experts and international students from the three countries in question applying a reflexive comparative perspective, thus making it possible to cross-reference individual voices.