bluuebunny/crossref_metadata_2025 huggingface dataset:
Deteksi dini kejadian sindrom metabolik melalui penyuluhan gizi, pengukuran Indeks Massa Tubuh (IMT) dan pemeriksaan tekanan darah serta kadar gula darah
Authors: Mulyani Nunung Sri , Fitriyaningsih Eva , Wagustina Silvia , Arnisam Arnisam
Published: April 2024

Sindroma metabolik merupakan kumpulan kelainan metabolik komplek yang muncul sebagai faktor risiko penyakit kardiovaskular serta diabetes mellitus tipe II. Komponen utama sindrom metabolik diantaranya adalah obesitas abdomen, peningkatan kadar glukosa darah (sewaktu dan atau puasa), peningkatan tekanan darah dan dislipidemia. Penyuluhan gizi pada pengabdian ini diharapkan dapat meningkatkan pengetahuan mengenai sindrom metabolik yang berhubungan dengan penyakit kardiovaskular. Pengabdian masyarakat ini telah dilaksanakan pada tanggal 19-20 September 2022 di desa Lamrukam kecamatan Peukan Bada Aceh Besar. Peserta pengabmas adalah ibu-ibu yang memiliki resiko sindrom metabolic sebanyak 25 orang. Kegiatan pengabmas terdiri dari pre test untuk mengetahui pengetahuan masyarakat tentang sindrom metabolic, pengukuran tinggi badan (TB) dan berat badan (BB) untuk mengetahui status gizi peserta pengabmas, pemeriksaan tekanan darah, pengukuran gula darah, penyuluhan gizi dan post test. Hasil, status gizi peserta overweight yaitu 12 orang (48%), sedangkan tekanan darah   dan kadar gula darah normal yaitu 18 orang (72%) dan 22 orang (88%). rata-rata pengetahuan peserta sebelum penyuluhan gizi yaitu 36 sedangkan setelah dilakukan penyuluhan gizi rata-rata pengetahuan peserta menjadi 64,8. Hal ini dapat disimpulkan adanya peningkatan pengetahuan peserta sebesar 28,8%. Kesimpulan, penyuluhan pada peserta pengabdian masyarakat dapat meningkatkan pengetahuan masyarakat cara deteksi dini kejadian sindrom metabolik.
Meningkatkan pengetahuan masyarakat Meunasah Krueng Kecamatan Ingin Jaya tentang bahan makanan yang mengandung formalin
Authors: Hadi Abdul , Ichsan Ichsan , Alfridsyah Alfridsyah , Khazanah Wiqayatun , Mulyani Nunung Sri
Published: April 2024

Sebagian besar konsumen tidak paham seberapa besar bahaya yang ditimbulkan akibat mengkonsumsi makanan yang mengandung bahan pengawet berbahaya, mereka tertarik pada bahan makanan seperti ikan dan daging yang tampak segar, berwarna cerah, kenyal, tidak berbau dan murah walaupun sebenarnya bahan makanan tersebut mengandung pengawet berbahaya. Metode : Metoda yang dilakukan di pengabdian masyarakat ini adalah metode penyuluhan tentang bahan makanan yang mengandung Formalin Hasil Kegiatan : Dari hasil perolehan nilai rata-rata pengetahuan dan sikap peserta yang mengikuti pre-test dan posttest terlihat bahwa ada peningkatan pengetahuan peserta sebesar 57,5% yaitu dari 37,5% menjadi 95%. Kemudian, terjadi peningkatan juga terhadap rata-rata sikap peserta sebesar 63,68% yaitu dari 33,04% menjadi 96,72%. Kesimpulan : Penyuluhan yang dilakukan sebanyak dua hari telah dapat menambah wawasan masyarakat serta dapat peningkatan pengetahuan dan sikap masyarakat menjadi lebih baik.
REKSIMIA (Gerakan Remaja Eksis Bebas Anemia) sebagai upaya pencegahan anemia pada remaja di Banda Aceh
Authors: Azizah Amelia Puteri Nur , Evaliani Evaliani , Surimadilla Surimadilla , Tiarisma Alfi , Ahmad Aripin , Annisa Devita
Published: April 2024

Remaja merupakan generasi penerus bangsa terutama pada remaja putri. Keadaan gizi pada remaja putri dapat berpengaruh terhadap kehamilannya kelak, juga terhadap bayi yang akan dilahirkannya. Salah satu masalah gizi yang paling sering dijumpai pada remaja adalah anemia. Masalah gizi remaja perlu mendapatkan perhatian khusus karena berpengaruh terhadap masalah gizi dewasa. Tetapi, masih kurangnya akses, sosialisasi dan edukasi tentang pencegahan anemia sehingga banyak remaja yang belum memiliki kesadaran akan pentingnya pencegahan anemia. Pengabmas ini menggunakan metode peer education dan edutainment yang dilakukan melalui tiga tahap pelaksanaan yaitu sosialisasi, pelatihan peer educator dan edukasi teman sebaya. Hasil yang dicapai yaitu pertama, setelah pelatihan peer educator terdapat peningkatan pengetahuan sebesar 43,6% , sikap 13,7%, dan keterampilan remaja 80% yang merupakan kategori baik, kedua terbentuknya modul bagi peer educator sebagai panduan dalam mengedukasi teman sebayanya. Ketiga, terbentuknya Peer Educator Reksimia di sekolah dan dibuktikan dengan SK pembentukan tim dari kepala sekolah. Melalui Peer Educator Reksimia dan kerjasama dengan pihak terintegrasi, maka akan mendukung potensi keberlanjutan program Reksimia kepada sekolah yang lain. Sehingga mampu mendukung upaya pemerintah dalam mengurangi angka prevalensi anemia dan mendukung poin ke 3 dalam SDGs terkait kehidupan sehat dan sejahtera.
Penggunaan media buku bergambar SOGI (menggosok gigi) dalam praktik menggosok gigi yang benar pada murid kelas V MIN 13 Aceh Besar
Authors: Niakurniawati Niakurniawati , Imran Herry , Nasri Nasri , Wilis Ratna
Published: April 2024

Kesehatan gigi dan mulut merupakan hal yang penting dalam kehidupan setiap individu termasuk pada anak, karena gigi dan gusi yang tidak dirawat dapat menggangu kesehatan tubuh lainnya. Hasil studi awal, dari wawancara terhadap 15 murid didapati 3 murid yang mengerti dan 12 murid tidak mengerti tentang cara, frekuensi dan waktu menyikat gigi yang baik dan benar. Penelitian ini bertujuan untuk mengetahui pengaruh media buku bergambar sogi terhadap pengetahuan dan praktik menggosok gigi yang benar pada murid kelas V MIN 13 Aceh Besar yang diambil secara total populasi. Desain penelitian ini adalah quasi experiment dengan rancangan pretest-postest terhadap dua kelompok yaitu kelompok intervensi 40 murid kelas V-A dan 40 murid kelompok kontrol kelas V-B. Pengumpulan data dan intervensi dilaksanakan di MIN 13 Aceh Besar pada tanggal 01 September sampai 07 September 2023 dengan menggunakan kuesioner dan lembar ceklist. Rentang waktu antara pretest dan postest selama sebulan. Analisis data menggunakan uji t-test. Hasil penelitian menunjukkan peningkatan yang signifikan terhadap pengetahuan terhadap kelompok intervensi dan kelompok kontrol (p=0,000) dengan selisih rata-rata (3,5) dan (0,3) sedangkan terhadap praktik kelompok intervensi dan kelompok kontrol (p=0,000) dengan selisih rata-rata (1,4) dan (0,23) tentang menggosok gigi yang benar. Disimpulkan bahwa media buku bergambar sogi dapat meningkatkan pengetahuan dan praktik tentang menggosok gigi yang benar. Diharapkan kepada murid dapat mempertahankan pengetahuan dan meningkatkan praktik tentang menggosok gigi yang benar dengan cara lebih banyak membaca dari berbagai sumber informasi dan menanamkan kesadaran diri sendiri akan pentingnya menggosok gigi.
Pendampingan remaja dalam pencegahan pernikahan usia dini di Desa Bukit Raya tahun 2023
Authors: Urnia Ega Ersya , Virawati Dini Indo , Haloho Cristinawati B/R
Published: April 2024

Angka pernikahan usia dini tertinggi di Kalimantan Timur terjadi di Kabupaten Kutai Kartanegara yakni sebanyak 268 kasus, disusul Samarinda 194 kasus dan Balikpapan 179 kasus. Angka Pernikahan Usia Dini pada wilayah Puskesmas Teluk Dalam adalah sebesar 64% atau 171 kasus. Sementara di Desa Bukit Raya tercatat remaja yang menikah pada usia dini adalah sebanyak 34 orang. Program Pelayanan Kesehatan Peduli Remaja (PKPR) tidak berjalan secara berkesinambungan karena keterbatasan tenaga kesehatan dilapangan. Pendampingan remaja untuk menumbuhkan kepedulian terhadap pernikahan usia dini belum pernah dilakukan. Membantu menurunkan angka kejadian pernikahan usia dini di Desa Bukit Raya. Membantu tenaga kesehatan dilapangan dalam melaksanakan Program Pelayanan Kesehatan Peduli Remaja (PKPR). Meningkatkan pengetahuan remaja mengenai dampak negatif pernikahan usia dini. Menurunkan angka kejadian pernikahan usia dini di Desa Bukit Raya dengan cara melaksanakan pendampingan remaja untuk menumbuhkan kepedulian terhadap pernikahan usia dini dan meningkatkan pengetahuan remaja dengan memberikan pendidikan kesehatan menggunakan media video dan leaflet. Sasaran pendampingan adalah Remaja di Desa Bukit Raya. Adapun jumlah remaja yang akan didampingi yaitu 40 remaja. Metode kegiatan dilakukan dalam beberapa tahap yaitu (1) tahap persiapan, (2) tahap pelaksanaan, (3) tahap monitoring (4) pendampingan keluarga (5) tahap evaluasi.
Screening test asam urat dan sosialisasi dampak emping melinjo (Gnetum gnemon L.) pada masyarakat Gampong Bak Aghu Kecamatan Seulimeum Kabupaten Aceh Besar
Authors: Wahab Irwana , Jumadewi Asri , Rizki Zuriani
Published: April 2024

Screening test penyakit asam urat perlu dilakukan. Masyarakat desa mitra yang menjadi wilayah binaan Poltekkes Kemenkes Aceh sebagai bentuk kontribusi pengabdian masyarakat dalam rangka memenuhi Tri Dharma Perguruan Tinggi. Hal ini menjadi urgen karena dari penjajakan awal diperoleh data meningkatnya pola konsumsi emping melinjo yang mengandung purin sebagai penyebab penyakit asam urat pada masyarakat desa Bak Aghu Kecamatan Seulimeum. Tujuan kegiatan pengabdian masyarakat ini adalah untuk melakukan screening test dengan pemeriksaan kadar asam urat dalam darah dan melakukan sosialisasi pada masyarakat bahwa emping melinjo dapat menyebabkan tingginya kadar asam urat. Tahapan awal yaitu melakukan screening test dengan pemeriksaan kadar asam urat dalam darah kemudian memberikan promosi kesehatan berupa sosialisasi emping melinjo yang dapat menyebabkan peradangan sendi. Hasil pengabdian masyarakat menunjukkan adanya perubahan kadar asam urat masyarakat dan pengetahuan masyarakat tentang kandungan purin dalam melinjo berdasarkan perbandingan hasil yang diperoleh sebelum dilakukan penyuluhan. Hal ini menyimpulkan gambaran bahwa penyuluhan bahaya mengkonsumsi Emping Melinjo (Gnetum gnemon L.) Pada Penyakit Asam Urat untuk meningkatkan derajat kesehatan masyarakat Gampong Bak Aghu kecamatan Seulimeum Aceh Besar.
Pelayanan asuhan kesehatan gigi dan mulut dalam penurunan debris index pada anak MIN 1 Kota Banda Aceh
Authors: Imran Herry , Niakurniawati Niakurniawati , Nasri Nasri , Wilis Ratna
Published: April 2024

Kesehatan gigi dan mulut diselenggarakan dalam bentuk kegiatan dengan pendekatan promotif, preventif, kuratif, dan rehabilitas yang dilaksanakan secara terpadu, menyeluruh, dan berkesinambungan. Status atau derajat kesehatan masyarakat ditentukan oleh beberapa faktor yang meliputi lingkungan, perilaku masyarakat dan pelayanan kesehatan. Berdasarkan hasil penelitian dan pembahasan yang telah disajikan bahwa hasil analisis statistik didapatkan bahwa tidak ada hubungan pengetahuan ibu dengan status kebersihan gigi dan mulut murid (p=0,15) dan ada hubungan sikap ibu (p=0,02) serta ada hubungan tindakan ibu dengan status kebersihan gigi dan mulut murid (p=0,01). Pengabdian masyarakat yang dilakukan bertujuan meningkatkan keterampilan anak dalam menyikat gigi untuk penurunan debris indek pada anak MIN 1 Kota Banda Aceh Banda Aceh. Bahan yang digunakan dalam kegiatan ini adalah sikat gigi dan pasta gigi. Kegiatan pengabdian berupa memberikan penyuluhan dan melaksanakan sikat gigi pada anak berkebutuhan khusus. Adapun hasil dari kegiatan ini adalah secara umum semua anak yang hadir dapat menerima penjelasan dan mempraktekkan cara menyikat gigi yang baik dan benar. Dapat disimpulkan bahwa terjadi peningkatan status kebersihan gigi dan mulut anak MIN 1 Kota Banda Aceh dan peningkatan keterampilan dalam menyikat gigi sehingga angka debris index menurun, diharapkan kepada anak MIN 1 Kota Banda Aceh agar menjaga kebersihan gigi dan mulutnya dengan cara menyikat gigi tiga kali sehari serta diharapkan kepada orang tuanya secara rutin memeriksakan kesehatan gigi dan mulut anaknya setiap 6 bulan sekali.
Penguatan percepatan penurunan stunting melalui pemberdayaan remaja peduli stunting
Authors: Wagustina Silvia , Arnisam Arnisam , Mulyani Nunung Sri , Hadi Abdul , Fitriyaningsih Eva
Published: April 2024

Angka Kejadian stunting di Indonesia masih cukup tinggi. Prevalensi stunting di Provinsi Aceh menempati posisi ke lima tertinggi dengan angka 33,2% menempati posisi ke lima tertinggi secara nasional.  Kabupaten Aceh besar merupakan salah lokasi focus stunting dari 13 kabupaten/kota yang telah ditetapkan oleh pemerintah. Untuk mencegah kejadian stunting ini, intervensi selanjutnya harus melibatkan pada remaja sebagai calon ibu. Keterlibatan remaja dalam upaya mengatasi dan mencegah stunting ini sesuai dengan program Badan Koordinasi Keluarga Beremcana Nasional (BKKBN) dalam bentuk remaja peduli stunting. Remaja peduli stunting ini diberdayakan sebagai konselor bagi remaja sebaya dan ibu yang mempunyai balita. Tujuan kegiatan untuk meningkatkan pengetahuan tentang stunting dan keterampilan remaja sebagai konselor remaja terkait stunting. Metode pelaksanaan dilakukan dengan pendekatan edukasi melalui pelatihan konseling gizi bagi remaja tentang stunting: pengkajian, perencanaan, intervensi dan evaluasi. Hasil, terjadi peningkatan pengetahuan remaja tentang stunting sebesar 33,3%. kemampuan memberikan konseling kepada remaja sebaya serta ibu yang mempunyai balita dengan menggunakan keterampilan dasar konseling meningkat sebesar 33,3%. Kesimpulan, setelah dilatih, remaja mampu memberikan konseling gizi tentang anemia gizi, KEK dan dampaknya terhadap stunting kepada remaja sebayanya dan kepada ibu balita.
The Concept of Love of Country in 19th-Century Painting
Authors: Utari Shela Dwi , Hudiyanto Reza , Wahyudi Deny Yudo
Published: April 2024

Love for the country does not only focus on the physical resistance carried out at that time but can also take other forms. In this case, painting artists realized their love for their homeland through visual aspects. This research explores the forms of the concept of love for the country in Indonesian painting, especially in the 19th century. This research uses the historical method with five stages: topic selection, heuristics, source criticism, interpretation, and historiography. The result of this research is that paintings in the 19th century illustrate the concept of patriotism as seen from the objects depicted. The object of the painting is not only fixated on the role and power of the colonial nation but also gives the impression that the Indonesian nation also has a role. This can be seen from some of Raden Saleh's paintings such as Daendels' potert, the painting Between Life and Death, and the painting of Prince Diponegoro's arrest, which gives the meaning that Indonesians also played a role in historical events that occurred at that time.
The Issue of Islamic Higher Education Development in Indonesia from 1945 to Present
Authors: Sugianto Sugianto , Ansori M Afif , Andari An An , Pribadi Joko , Nisa Khairun
Published: April 2024

This research aims to analyze the issues surrounding the development of Islamic Higher Education through the application of literature review methodology. Literature review methodology involves collecting and analyzing relevant literature and references to understand the associated issues within the context of Islamic higher education institutions. The study adopts a qualitative approach by analyzing various literatures, journals, books, and related theoretical sources. The data obtained are descriptively analyzed to identify patterns and trends in the dynamics of Islamic higher education institutions. The findings reveal that these institutions face complex dynamics in addressing contemporary challenges. Furthermore, this abstract identifies challenges encountered by Islamic Higher Education institutions, such as competition with non-Islamic educational institutions, enhancing the quality of human resources, funding, and accreditation issues. These challenges require innovation and appropriate strategies to ensure the sustainability and success of Islamic Higher Education institutions. In conclusion, this abstract highlight the dynamics occurring within Islamic Higher Education institutions.
Emisiones vehiculares de dióxido de carbono al cruzar una zona fronteriza al noroeste de México, antes y durante la incidencia del COVID-19
Authors: Flores-Jiménez David E. , Santos-Gómez Ma. De los Ángeles , Santillán-Soto Néstor
Published: April 2024

Se analiza el comportamiento de las emisiones vehiculares de dióxido de carbono en dos puertos
fronterizos de Mexicali, Baja California, México, antes y durante la incidencia del COVID-19 en él
periodo 2019-2020. Se propone un Índice Relativo de Movilidad Vehicular (IRMV) para cuantificar
la influencia de las restricciones de acceso a Estados Unidos sobre las emisiones vehiculares en ambos
puertos. Estas se estiman con el método propuesto por el Panel Intergubernamental de Cambio
Climático (IPCC), obteniendo que en 2019 fueron mayores. El IRMV muestra que durante mayo agosto
del 2020 y octubre-diciembre del mismo año, se reduce el impacto de las medidas
implementadas, observando que, en mayo-junio y noviembre-diciembre, respectivamente, se alcanzan
los niveles máximos de casos COVID-19 y de emisiones.
Análisis del microbioma de las garrapatas de ganado, un nuevo abordaje basado en metagenómica
Authors: Aguilar-Díaz Hugo , Quiroz-Castañeda Rosa Estela
Published: April 2024

Las recientes investigaciones metagenómicas de garrapatas han revelado que sus microbiomas poseen una diversidad microbiana conformada por endosimbiontes y patógenos (patobioma), causantes de enfermedades en el humano y otros animales. Las garrapatas son vectores de diversas enfermedades al ganado bovino, por lo que un estudio de mayor alcance permitirá elucidar la composición de su microbioma con la finalidad de proponer nuevas estrategias de control y prevención como el desarrollo de vacunas antigarrapata. Este proceso resulta ser prometedor y posee como base la identificación de bacterias fundamentales para la supervivencia del vector. De acuerdo con este contexto, se presenta el abordaje metagenómico aplicado a las garrapatas para la identificación de la microbiota y el respectivo microbioma.
La persistencia del medioevo: ensayo sobre el pensamiento científico y académico en la era de la posverdad
Authors: Carrera Aguila Ricardo
Published: April 2024

Se plantea una gran similitud entre la forma de construir y validar el conocimiento entre los periodos de la alta Edad Media y la época actual, a partir de un análisis crítico de la forma en que los medios masivos de comunicación y la opinión pública actúan sobre los pensamientos académicos y científicos. El análisis considera cuatro elementos: la posverdad como concepto actual, las consecuencias mediáticas que conlleva, la comparativa con el pensamiento medieval y el análisis prospectivo de nuestra realidad mediática. Como resultado, se concluye que un concepto aplicado inicialmente a la política estadounidense del 2010, se ha convertido en bastión de ideas y disparates que han devenido en un comportamiento irónicamente similar, entre el dos periodos históricamente disímiles.
Primary aldosteronism and cardiovascular risk. Review
Authors: Tovkai O. A. , Grossman A. , Yuzvenko T. Y. , Pankiv V. I.
Published: April 2024

Primary aldosteronism (PA), a significant and curable cause of secondary hypertension, occurs in 5—10% of hypertensive patients, with prevalence dependent on the severity of hypertension. The main etiologies of PA include bilateral idiopathic hypertrophy (BIH) and aldosterone‑producing adenoma (APA), while less common causes include unilateral hyperplasia, familial hyperaldosteronism (FH) types I—IV, aldosterone‑producing carcinoma, and ectopic aldosterone synthesis. This condition, characterized by excessive secretion of aldosterone, leads to increased reabsorption of sodium and water along with potassium loss, culminating in the distinct clinical signs of elevated aldosterone, suppressed renin, and hypertension. It should be noted that hypokalemia is present in only 28% of patients with PA and is not the main indicator. The association of PA with an increased risk profile for cardiovascular disease, regardless of blood pressure level, is notable. Patients with PA show an increased rate of cardiovascular events compared to patients with essential hypertension, adjusted for age, sex, and blood pressure level. Despite its prevalence, PA often remains undiagnosed, highlighting the need for enhanced screening protocols. The diagnostic process for PA involves a three‑pronged assessment: the aldosterone/renin ratio (ARR) as the initial screening tool, followed by confirmatory and subtype tests. A positive ARR requires confirmatory testing to rule out false positives. Examination to detect PA should be carried out in patients with arterial hypertension: moderate (> 160—179/100—109 mm Hg) or severe (> 180/110 mm Hg); resistant to treatment; with idiopathic or diuretic‑induced hypokalemia; with an accidentally diagnosed tumor of the adrenal glands; if first‑generation relatives are diagnosed with PA, or family history indicates early onset of arterial hypertension, or cerebrovascular disorders at a young age (< 40 years); with accompanying obstructive sleep apnea.
Relationship between pathohistological characteristics of the tumor and distant metastasis of differentiated thyroid cancer
Authors: Tovkai O. A. , Palamarchuk V. O. , Vovk K. O. , Smolovyk N. V. , Yatsiv A. R. , Kuts V. V. , Bodnar M. R.
Published: April 2024

Papillary thyroid cancer has the most favorable prognosis for patients. According to the recommendations of the National Comprehensive Cancer Network (NCCN), organ‑sparing surgery can be performed for such patients without radioactive iodine therapy (RIT). However, some factors, for example, vascular invasion, multifocality, the presence of regional metastases, etc. increase stratification risks for the patient and give the reason to perform more voluminous surgical interventions and conduct RIT. With differentiated thyroid cancer (DTC), the 5‑year and 10‑year overall survival rates reach 100% and 96%, respectively.
Objective — to investigate the relationship between the pathohistological characteristics of the DTC tumor and distant metastasis.
Materials and methods. The study involved 522 patients aged 4 to 79 years (the mean age 40.2±0.6 years) after previous thyroid cancer surgery and RIT. Patients were divided into two groups depending on the presence of distant metastases: 28 (5.4%) with distant metastases and 494 (94.6%) patients without distant metastases.
Results. Using the data of pathohistological findings, both groups were compared according to the following criteria: pathomorphological DTC subtype, vascular invasion, other extraordinary invasion, multifocality, the size of the primary tumor, the size of the largest focus and the total size of foci for multifocal cancers, the number and maximum size of metastases in the central and lateral lymphatic collectors of the neck.
Conclusions. No significant relationship has been found between the pathomorphological subtype of differentiated thyroid cancer, the presence of vascular and extra‑organ invasion, and the presence of distant metastases, but a relationship was found with multifocality. In the group of patients with distant metastases, a larger size of the primary focus, and a larger size and number of regional metastases were determined.
Identification and monitoring of laryngeal nerves: technologies and problems. Review
Authors: Shidlovskyi V. O. , Shidlovskyi O. V. , Dyvak A. M. , Pryvrotskyi V. M. , Morozovych I. I.
Published: April 2024

The review paper is devoted to an important problem of surgical treatment of thyroid diseases: avoiding injuries to the nerves of the larynx and the consequences associated with them. One of the ways to solve it is the identification and monitoring of nerves during surgery. An analysis of existing methods and technologies used for identification and monitoring of laryngeal nerves has been carried out. The issues of effectiveness and expediency of their application were considered. The definition of the terms «nerve identification» and «neuromonitoring of laryngeal nerves» has been outlined. The term «nerve identification» defines the procedure for identifying a nerve among the tissues of a surgical wound. Neuromonitoring is the constant monitoring of the nerve during the operation. In the prevention of laryngeal nerve injuries, it is important to combine these two actions and follow their sequence, the nerve identification should be the first, following by its monitoring during the surgery. The authors singled out two stages in the processes of identification and neuromonitoring of laryngeal nerves, electrical stimulation and recording the results of electrical stimulation. A detailed description of each of the stages is given, as well as methods and means of their implementation, technologies, positive and negative aspects. The author’s method of identification and neuromonitoring of laryngeal nerves using a laryngeal mask is described, which is based on the neurochronaxic theory of sound formation. The authors conclude the advisability of the identification and neuromonitoring of laryngeal nerves during operations on the thyroid gland, as they allow reducing the number of paresis of the larynx. Modern IONM technologies do not provide absolute accuracy. Some of them are technically complex, and the obtained results depend on many factors that significantly affect the reliability. The need to create a reliable, physiologically based, easy‑to‑use technology for identification and neuromonitoring of laryngeal nerves is emphasized.
Surgical rehabilitation of patients with Crohn’s disease
Authors: Poyda O. I. , Melnyk V. M.
Published: April 2024

Objective —  to enhance the outcomes of surgical rehabilitation for patients with Crohn’s disease through the improvement and implementation of organisational measures as well as general and specialised surgical strategies.

Materials and methods. The study focused on the development of organisational measures as well as general and specialised surgical rehabilitation procedures for Crohn’s disease. The research was conducted to determine the scope of radical surgical interventions for complications resulting from segmental lesions with extensive damage to the intestinal tract. The study also aimed to develop methods of restorative, reconstructive and restorative operations that would reduce the frequency of postoperative complications, disease recurrence, digestive disorders in the intestinal tract, malabsorption, and anal incontinence. Additionally, the study aimed to improve the functional outcomes and quality of life for operated patients.

Results. A total of 53 patients with Crohn’s disease — 28 (52.8%) men and 25 (47.2%) women — were operated on using specially designed surgical rehabilitation techniques. The patients undergoing surgery ranged in age from 19 to 45. 32 (60.4%) patients had segmental resections, while 21 (39.6%) had extensive resections. 8 (15.1%) patients underwent restorative operations, while 40 (75.4%) had reconstructive operations. A lifelong ileostomy was formed in 5 (9.4%) patients. Postoperative complications were observed in 12 (22.6%) patients, and disease relapses in 5 (9.4%) patients. One (1.8%) patient died after surgery. Positive functional outcomes, including improved digestion in the intestinal tract, normal absorption, and preservation of anal retention, were noted following restorative and reconstructive‑restorative operations.

Conclusions. Organisational measures as well as general and specialised surgical rehabilitation strategies for Crohn’s disease allowed for more effective diagnosis and treatment of postoperative complications, better prevention of disease recurrence, improved digestion in the intestinal tract, normalised absorption processes, and preservation of anal retention. Following the implementation of specially designed surgical rehabilitation techniques, 20.7% and 1.8% of patients experienced early and late postoperative complications, respectively. Additionally, there were occurrences of postoperative mortality in 1.8% of patients and relapses in 9.4%. Severe forms of reflux ileitis, postcolectomy syndrome, and secondary anal incontinence syndrome were not observed.
Changes in the antibiotic-resistant properties of pathogenic microorganisms in patients with purulent-necrotic wounds against the background of type 2 diabetes when using a probiotic antiseptic
Authors: Ioffe O. Y. , Stetsenko O. P. , Kindzer S. L. , Kryvopustov M. S. , Tsyura Y. P. , Prykhodko Y. S.
Published: April 2024

Antibiotic resistance remains a serious problem, leading to millions of deaths every year. The increasing prevalence of type 2 diabetes mellitus (T2DM) is contributing to the continued spread of this problem. Ukraine, like other countries, feels the consequences of this problem. Over the past ten years, the number of patients with T2DM has doubled, and diabetes is already the cause of disability and death for thousands of people. Complications of T2DM, such as diabetic foot syndrome, often require surgery and antibacterial therapy. New research shows the prospects of using probiotic antiseptics based on lactic acid bacteria of the genus Bacillus in the treatment of wounds, which may open new opportunities to combat this problem and improve treatment outcomes.
Objective — to analyse changes in the antibiotic‑resistant properties of pathogenic microorganisms in patients with purulent‑necrotic wounds in type 2 diabetes mellitus.
Materials and methods. The study, which was conducted at the Department of General Surgery No. 2 of Bogomolets National Medical University in Kyiv City Clinical Hospital No. 3, included 229 patients with purulent‑necrotic wounds and type II diabetes. A total of 229 patients were randomly divided into two groups, with one group receiving probiotic antiseptics and the other traditional chemical antiseptics, with subsequent analysis focusing on changes in antibiotic‑resistant properties against P. aeruginosa and K. pneumoniae. Antibiotic‑resistant properties were evaluated through microbiological examination, revealing significant changes in resistance patterns among patients treated with probiotic antiseptics compared to those using traditional chemical antiseptics, assessed using statistical methods including the Student’s t‑test and Wilcoxon W‑test.
Results. When the first subgroups were compared on the first day, there was no statistically significant difference in the levels of P. aeruginosa wound contamination (p=0.671). On the seventh day, there was a statistically significant difference between contamination levels (p<0.05) and the emergence of sensitivity to reserve antibiotics (p<0.05). On the 14th day, there was a statistically significant difference between contamination levels (p<0.05) and the emergence of sensitivity to reserve antibiotics (p<0.05).
Conclusions. Probiotic antiseptics have a statistically significant advantage over chemical antiseptics in terms of reducing contamination and emergence of antibiotic sensitivity in patients with purulent‑necrotic wounds in type 2 diabetes mellitus.
Hnat Mykhailovych Matyashin: the difficult path of a soldier, surgeon, scientist, and teacher
Authors: Zavernyi L. G. , Tsiura Y. P. , Kryvopustov M. S. , Tarasiuk T. V.
Published: April 2024

The life and professional path of Professor Hnat Mykhailovych Matyashin: a scientist and surgeon, Doctor of Medical Sciences, Honoured Scientist of the Ukrainian SSR, Honoured Doctor of the Ukrainian SSR, Chief Surgeon of the Ministry of Health of the Ukrainian SSR, Head of the Department of Faculty Surgery of the Kyiv Medical Institute.
Contemporary hypolipemic therapy: possibilities of novel hypolipemic drugs in correction of lipid metabolism disorders. Review
Authors: Chernyshov V. A.
Published: April 2024

Dyslipidemia plays a role of significant risk factor for development and progression of cardiovascular diseases. Today several classes of hypolipemic drugs with evidenced effectiveness are used. But some patients don’t tolerate medicines with high efficacy or can’t achieve the targeted blood lipid profile levels even in case of the use of maximal doses or combined therapy. This necessitates the creation of new hypolipidemic agents.
The review is devoted to discussion of new directions of influence on impaired lipid metabolism through creation of new classes of hypolipemic drugs with some perspectives of effective correction of lipid factors of cardiovascular risk (CVR) in cases of impossibility to achieve the targeted levels of low‑density lipoprotein cholesterol (LDL‑C) or there is a residual CVR caused by elevated serum triglyceride (TG) levels and/or low levels of high‑density lipoprotein cholesterol (HDL‑C).
Among the novel drugs for hypercholesterolemia (HCE) correction, considerations are given for some mechanisms of action and efficacy of application of proprotein convertase subtilisin‑kexine type 9 (PCSK9) inhibitors as well as bempedoic acid (adenosine triphosphate citrate lyase inhibitor) and inclisiran, a small synthesized interfering ribonucleic acid (RNA) with its ability to blockade genes‑regulators of hepatic PCSK9 activity. The novel agents for hypertriglyceridemia correction, discussed in the review, include icosapent ethyl (a high purified and firm ester of ethyl‑eicosapentoenic acid), pemafibrate (the first selective modulator of α‑receptors activated by peroxisome proliferator), apolipoprotein C‑III (ApoC‑III) inhibitors (volasenorsen, olesarsen), mipomersen (antisense nucleotide for matrix RNA of apolipoprotein B‑100), lomitapide (inhibitor of microsomal TG transfer protein) and inhibitors of angiopoietin‑like protein 3 (ANGPTL3) (evinacumab, vupanorsen). Among the new approaches to HDL‑C elevation an attention is paid to the experimental and clinical investigations of recombinant HDL, agents with recombinant lecithin‑cholesterol‑acyl‑transferase (LCAT), and apolipoprotein A‑I (ApoA‑I) mimetic peptides. For the lowering of blood lipoprotein(a) (LP(a)) level the possibilities of pelacarsen, an antisense oligonucleotide for matrix RNA of apolipoprotein(a) (apo(a)) contained in LP(a) molecule and olpasiran, a small interfering RNA for LP(a) molecule inhibited apo(a) synthesis are uncovered. A high probability of clinical application in the nearest future will have novel drugs approved by US Food and Drug Administration (FDA) and European Medicines Agency (EMA) such as bempedoic acid and inclisiran for HCE correction as well as lomitapide for the treatment of familial HCE.
Avaliable data for adverce cardiac events prognostication after ST segment elevation myocardial infarction
Authors: Petyunina O. V. , Kobets A. V.
Published: April 2024

The treatment of acute myocardial infarction (AMI) is aimed at the long‑term survival of patients, so attention should be given to predicting adverse outcomes, specifically the development of heart failure, recurrent AMI, cardiovascular death, and so on. The combination of various data obtained in recent decades has helped improve prognosis, but challenges with long‑term survival after ST segment elevation myocardial infarction (STEMI) still exist.
Objective — to find the optimal combination of data collected from patients with STEMI and prospectively analyzed during one‑year observation to improve the quality of prognostication.
Materials and methods. One hundred and twenty‑eight enrolled patients visited research center to clinical examination and estimation of left ventricular (LV) function in 365±14 days follow up period after STEMI. End points such as major adverce cardiac events (MACE) — composite of cardiovascular death, recurrent MI, newly diagnosed heart failure, rhythm, and conduction disturbances were estimated. Primary percutaneous coronary intervention was successful, and all included patients had TIMI (Thrombolysis In Myocardial Infarction) >2. Patients was divided into two cohorts depending on the presence of MACE: global longitudinal strain and mechanical dispersion are independent factors of it (p=0.0006 and p <0.0001respectively).
Results. We found the optimal combination of different data for prognostication of adverce outcome after 1 year after STEMI, among them occurred global longitudinal strain, left atrium volume index, left ventricular end diastolic diameter, mechanical dispersion, LV ejection fraction. They all reflect different hemodynamic sides of LV remodeling after STEMI.
Conclusions. The model is simple and avaliable for use in medical practice.
To the honored memory of outstanding scientists of the medical community
Authors: Fadieienko G. D. , Myloslavsky D. K. , Gridasova L. M. , Kyleshova O. M. , Fedotova T. A.
Published: April 2024

The review of the history of therapy is dedicated to the outstanding scientists, jubilarians of the year 2024: L. T. Academicians Mala (1919—2003), V. V. Frolkis (1924—1999) and O. V. Korkushko (1929—2024). Their achievements considered in the field of cardiology, therapy, age‑related physiology, and clinical gerontology, attention is emphasized on their professional cooperation, personal relationships, and fruitful activities related to the formation of the Academy of Medical Sciences of Ukraine, and on the State Prize of Ukraine in Science and Technology, jointly received in 2003.
Effectiveness of Asthmagan administration in the complex therapy of chronic obstructive pulmonary disease
Authors: Maksymets T. A. , Horbey A. T. , Karpyshyn N. V. , Bodrevych B. B. , Sklyarov E. Y.
Published: April 2024

Ganoderma is a medicinal mushroom that has been used in traditional Chinese medicine for centuries. It contains a wide range of biologically active therapeutic molecules that have an anti‑inflammatory, immunomodulatory effect and contribute to the normalization of respiratory tract function.
Objective — to evaluate the effectiveness of the Asthmagan drug in the complex therapy of chronic obstructive pulmonary disease (COPD).
Materials and methods. Examinations involved 40 hospitalized patients with a verified diagnosis of COPD, aged 18 to 70 years. In addition to standard examinations, leukotriene B4 (LTB4) was determined. Asthmagan capsules were added to the scheme of complex inpatient and outpatient treatment.
Results. On admission, patients complained of breathlessness and cough with wheezing and sputum production. Blood tests showed leukocytosis, elevated ESR, hyperfibrinogenemia, and increased C‑reactive protein levels. According to the results of the correlation analysis, positive correlations were found between pro‑inflammatory markers and negative correlations between LTB4 and external respiration indicators. A tendency to LTB4 reduction was noted. After the treatment, positive dynamics were observed in all patients, and in the group of patients with Asthmagan inclusion, there was a significant improvement in external respiration function and all components of the quality of life according to the St. George’s Respiratory Questionnaire (SGRQ). Tolerability of Asthmagan was positive, side effects were not recorded.
Conclusions. During the inpatient treatment of patients with COPD with the inclusion of the drug Asthmagan, regression of complaints and clinical manifestations of COPD, a decrease in the level of pro‑inflammatory markers and a tendency to LTB4 levels reduction were noted. Improvement in the quality of life along with a significant increase in the external respiration indicators testified the increase in the effectiveness of COPD treatment by including Asthmagan in the complex treatment.
Microenterpreneur women's resilience in Covid-19 pandemic era
Authors: Sapiie Astrid Regina , Handoyo Seger
Published: April 2024

During the Covid-19 pandemic, many families experienced crisis due to husband’s lost income, having to lose their jobs despite of their position as the breadwinner of the families. In order to cope with the changing circumstances, wives have choices to endure, leave their husbands, or try to keep the family afloat by helping their husbands in fulfilling the needs of their families. Some of them chose to start culinary micro-businesses with minimal capital, relying on their everyday cooking skills. This research was aimed to study the resilience of research subjects as housewives who choose to be a micro-entrepreneurs during the Covid- 19 pandemic. The current research subjects were middle-aged housewives who supported their families during the pandemic by selling homemade foods and becoming motorcycle ride-hailing drivers. The research was conducted qualitatively (case study) as well as quantitatively and utilized both observation and interview methods, together with Connor-Davidson resilience questionnaire as comparison data. The result of the study showed that the research subjects were resilience persons. They are energetic strong-willed individuals who have been trained to work hard ever since childhood. Life experiences taught them how not to give up, and they believe that the future will be better because the Almighty God will always help to provide sustenance.

Keywords: resilience; housewive; micro entrepreneurs
Hubungan Self Regulation Dengan Impulsive Buying Item di Game Online Pada Masa Dewasa Awal
Authors: Aditya Danar Tresna
Published: April 2024

Penelitian ini bertujuan untuk mengetahui hubungan dari self regulation dengan impulsive buying item di game online. Data penelitian ini diperoleh 115 responden merupakan pemain game online dan 89 pernah melakukan pembelian pada item game online. Teknik sampling yang digunakan pada penelitian ini adalah non-probability dengan metode accidental sampling. Penelitian ini menggunakan skala self regulation dan impulsive buying dengan hasil analisis data korelasi r = -0.139 (p < .01) menggunakan spearman’s rho. Hal ini menunjukkan bahwa ada hubungan negatif yang signifikan antara self regulation dengan impulsive buying terhadap item di game online pada masa dewasa awal yang mengartikan bahwa semakin tinggi self regulation seseorang maka semakin rendah perilaku impulsive buying. Hal ini menyatakan bahwa self regulation memiliki peran penting bagi pemain game online di usia dewasa awal untuk menahan perilaku saat berbelanja.
Dynamics of the Emergence of Solidarity among Farmers in Trisik Galur Kulonprogo Hamlet
Authors: Shidqi M Hizbullah Ash
Published: April 2024

Solidarity in an area that is left behind is very important because individuals are in an area that is an area that is left behind from several other areas around it. Farmers previously had to face a life that could be said to be very deprived, difficult challenges and obstacles in living their lives, such as insults from outside and sometimes rejection, lack of resources, and living a life of deprivation. This research focuses on the depiction of teacher persistence in the coastal areas of Berareh Island. This research uses snowball sampling with three recommended subjects. This research uses qualitative methods with descriptive phenomenological research (PFD). The data collection technique used was observation and semi-structured interviews. The data analysis technique used is phenomenological analysis with Giorgi's six stages. Based on the findings of the synthesis themes through descriptive phenomenological analysis (DPA), three essential themes were found from the three participants, namely Solidarity, Unity, and Helping.

Keywords : solidarity, farmer, Trisik
Hubungan antara self efficacy dengan psychological well being pada dosen
Authors: Hartono Salsabillah Amalia Putri
Published: April 2024

Penelitian ini bertujuan untuk menganalisis hubungan antara Self Efficacy dengan Psychological Well Being pada dosen. Populasi pada penelitian ini sebesar 141 dosen dengan jabatan struktural di Universitas 17 Agustus 1945 Surabaya. Partisipan pada penelitian ini adalah 30 dosen dan teknik pengambilan data pada penelitian ini menggunakan teknik purposive sampling. Pengumpulan data dilakukan dengan memberikan skala yang terdiri dari skala Self Efficacy dan skala Psychological Well Being menggunakan google form dan intrumen pengumpulan data menggunakan skala likert. Berdasarkan analisis data yang menggunakan analisis statistik parametrik, yaitu teknik korelasi product moment dengan bantuan SPSS versi 25 IBM for windows. Hasil uji korelasi antara variabel Self Efficacy (X) dengan variabel Psychological Well Being (Y) diperoleh skor koefisien sebesar rxy=0.883 dengan signifikansi 0.000 (p<0.01). Artinya terdapat hubungan positif yang signifikan antara Self Efficacy dengan Psychological Well Being. Hipotesis pada penelitian ini berbunyi “hubungan positif antara Self Efficacy dengan Psychological Well Being pada dosen” dapat diterima.
Perceived supervisor support dan job insecurity dengan change engagement pada karyawan Badan Usaha Milik Negara: Menguji peran mediasi self-efficacy
Authors: Musa Nurmuliasneny , Fajrianthi Fajrianthi , Sami’an Sami’an
Published: April 2024

This writing aims to find out whether there is a correlation between perceived supervisor support and job insecurity on change engagement and self-efficacy as a mediator variable for Indonesian BUMN employees. This research involved 351 employees of state-owned companies who were determined using accidental sampling techniques. The research instrument used four scales, namely the Change Engagement Scale, the short version of the Scale of Perceived Supervisor Support (SPSS), the short version of the Job Insecurity Scale (JIS), and the Occupational Self Efficacy Short Version Scale. Data analysis in this writing uses path analysis using Jamovi. Based on the results of data analysis, there is a direct and indirect influence between perceived supervisor support on change engagement through self-efficacy, but there is no significant direct or indirect influence of job insecurity on change engagement through self-efficacy. The results of this research can be a reference for companies, especially BUMN regarding the importance of change engagement and other factors in intervening in organizations and employees.
Regulasi emosi dan perilaku agresi siswa: Budaya kehormatan sebagai mediator
Authors: Domino Primus , Hanurawan Fattah , Eva Nur
Published: April 2024

This research aims to determine the role of honor culture in mediating emotional regulation and students' aggressive behavior at school. The research participants were 245 students at high schools in Manggarai Regency, Flores, NTT, Indonesia who were recruited using purposive judgment sampling techniques. Research data collection used an aggression behavior scale, an emotional regulation scale and a culture of honor scale. All scales have been validated using Confirmatory Factor Analysis (CFA). Data analysis used a mediation model regression, with the help of the SPSS For Windows 3.5.2 program. The research results show that honor culture plays a significant role in mediating the relationship between emotional regulation and students' aggressive behavior. Educators should empower a culture of honor to improve students' emotional regulation so that they do not behave aggressively at school.
Strategi solve it dan kemampuan pemecahan soal cerita pada siswa: Menguji moderasi working memory, inhibitory control dan shifting
Authors: Siregar Nani Restati , Wimbarti Supra , Kusrohmaniah Sri
Published: April 2024

The current research aims to determine the effect of (1) the solve its strategy on the ability to solve math story problems moderated by working memory; (2) the solve its strategy on the ability to solve math story problems moderated by inhibitory control; (3) the solve its strategy on the ability to solve math story problems moderated by shifting. This experimental research used an untreated control group design model with a dependent pretest and posttest. Participants in the research were students being 4th-grade elementary school students in the city of Yogyakarta. The ability to solve story problems was measured using the test of mathematical ability (TOMA), the backward digit span task to measure working memory capacity, and the matching familiar figure test to measure inhibitory control and shifting capacity using the Wisconsin card sorting test. Data analysis uses partial least squares (PLS). The research results showed that only the moderating effect of inhibitory control was proven to support the influence of the solve-it strategy on the ability to solve math story problems. Implications for further research are discussed.