bluuebunny/crossref_metadata_2025 huggingface dataset:
El absurdo quijotesco en Madame Bovary y El proceso.
Authors:   Universidad de Guadalajara (MÉXICO), Godínez Romo Emmanuel Alejandro
Published: July 2021

When Cervantes was writing the Quijote perhaps he did not expect the scope that the adventures of the knight errant would have. In this article is pretended to track the Cervantine influence trough the structure and the characters in two of the most important works in the nineteenth and twentieth centuries: Madame Bovary by Gustave Flaubert and The Trial by Franz Kafka. It is possible to establish a link between these authors with Cervantes thanks to Flaubert and Kafka show or confessed they read Don Quixote.
La suave Patria: un poema posrevolucionario.
Authors:   Universidad de Guadalajara (MÉXICO), Murillo Andrea
Published: July 2021

The present work aims to point out that La suave Patria (1921) by Ramón López Velarde is a poem in which not only is there an affable song to the homeland, a predominant reading since its publication, but verses of social criticism with those who extol the necessary nationalist love at a time of national restructuring, such as was the post-revolutionary period in Mexico. In this way, it is true to point out that there is a patriotic loa in the text, thanks to the recurrence of traits of loving association with respect to the place of origin, but, also, it is correct to consider the evidence in the verses of a representation of the context in conflict to which it belongs, being irony the main tool that veils this criticism and the constant contradictions that give shape to this piece from Lopez-Velarde.
Olvido, rechazo y marginación en dos obras del teatro histórico mexicano: Felipe Ángeles de Elena Garro y El día más violento de Bárbara Colio.
Authors:   Universidad Autónoma Metropolitana- Iztapalapa (MÉXICO), Torres Miguel Ricardo
Published: July 2021

Felipe Ángeles by Elena Garro and Bárbara Colio’s El día más violento are two works that address somewhat dark characters in the history of the Mexican Revolution. Both pieces are about characters that have not been included in the worldview of the revolutionary nationalist apparatus, perhaps because they are women, as in the case of Colio's piece, or for daring to question the triumphs of that gesture, such as the piece on the hidalguense mythical General. Although there is a separation of more than 40 years, the writing of Garro and that of Colio weaves bridges, both in the feminine vision of mexican dramaturgy, and that of the historical heroes and who, despite being rejected, forgotten or marginalized characters, the theater has gradually offered them a little poetic justice.
Etiquetas discursivas y categorización de expresiones lingüísticas precedentes.
Authors:   Universidad Nacional de Río Cuarto. (ARGENTINA)., Bonnet Marcela , S. González Daniela ,   Universidad Nacional de Cuyo. (ARGENTINA).
Published: July 2021

In this paper, we study the processes of categorization of preceding voices trhow discursive labeling procedures. This anaphoric procedures can be understood as a type of paraphrasic reformulation used by the students by labeling information from several sources. The analysis is based on a description of the use of these mechanisms beginning with the manual identification of 70 labels in a corpus of 15 texts with monographies and essays features, written the students of different disciplines of the Language and Literature carrers of Río Cuarto University in 2015. The texts were produced as a proof of accreditation of curricular spaces. The use of these resource allows us to entrust the metadiscoursive, epistemic and axiologic burdens that they support when they reformulate and interprete other people's discourses. Results show that in the re-elaboration and conceptual appropiation of the knowledge, it is, at the same time, reformulated and constructed.
Hacia una correcta delimitación de las libertades negativas en el contexto neoliberal.
Authors:   Universidad Complutense de Madrid. (ESPAÑA)., Cano Cabildo Sissi
Published: July 2021

Towards a correct delimitation of negative freedoms in the neoliberal context In this work I propose to analyze what would be the correct limits of negative freedoms to reconstruct our civic culture based on respect, recognition, justice and ecological responsibility. Throughout history we had seen many dictatorial forms of government where there was no margin for freedom while we are currently seeing in the neoliberal context practically the opposite, the legitimation of unlimited negative freedoms, especially with regard to freedom of expression and private property, resulting in a rapacious individualism that underestimates respect, justice and rights of others. It is no small thing…
Pensar la violencia. Los lectores de Benjamín.
Authors:   Universidad de Guadalajara (MÉXICO), López Salas Jesús
Published: July 2021

In what follows the reader will find an exposition of Benjamin's text For a Critique of Violence, the interpretation made by Derrida, Honneth, Žižek, among others, as well as Bernstein's comment on those readings. Derrida has associated the Benjamin text with the "final solution", grouping it into the forms of thought that justify or make possible acts similar to those facts. Honneth looks for an affable outlet, turning towards a proposal for a cultural revolution. Žižek associates the resentment that humans experience to explain historical events, which are examples of pure or divine violence, which are caused by love that seeks good. Bernstein will accept the reading of Derrida, which he considers a product of imagination. He appreciates Honneth's performance, he finds it enlightening. He rejects the idea of reducing guilt to the conscience of the person responsible for violent acts, who silently and autonomously judges himself for the acts committed, seems to him inadmissible; he considers that violence should be a community discussion supported by fallibilist pluralism.
La Concretización de la Justicia Ambiental: Caso del Rio Santiago en los Municipios de El Salto y Juanacatlán
Authors:   Universidad de Guadalajara. (MÉXICO)., Souza Mosqueda Elizabeth Leticia , Moreno Reynaga Martín ,   Universidad de Guadalajara (MÉXICO)., Ceceña Altamirano Angelica Jesús ,   Universidad de Guadalajara (México)., Ramírez Ramírez Cynthia ,   Universidad de Guadalajara. (México)., Franco Vázquez Daland Alexis ,   Universidad de Guadalajara (MÉXICO).
Published: July 2021

This research work develops the problem of the application of the legal framework of the right to water for its protection and reparation as well as to the environment, since this is closely related to the first mentioned right, when there is an affectation. For this, we study the case of the Santiago River, one of the most important bodies of water in Mexico and with the longest length.For this reason, when we talk about the Santiago River we will refer to the body of water located in the municipalities of Juanacatlán and Salto del State of Jalisco, which, for a long time, was contaminated by dumping various types of substances, without measures being taken to reduce said activity to date. This is done with the study of the national and international legal framework on the matter, to later develop the circumstances in which they caused the damage to the River, and like these, they encouraged the various authorities to issue resolutions trying to repair the damage. Despite the existence of such determinations, they are not sufficient for the protection of this right, so in the end we propose the creation of an environmental court that is capable of solving these types of problems.
Los estereotipos sobre los músicos en Guadalajara: la percepción de los profesionales de la música y la incidencia en sus carreras.
Authors:   Universidad de Guadalajara (MÉXICO)., Machillot Didier
Published: July 2021

In this article, we will question stereotypes regarding musicians and the influence that they may have in the development of a professional career. In order to do this, we will try to answer three questions: Which are the prevailing stereotypes about musicians in Mexico and particularly in Guadalajara? How do these harmful stereotypes affect their career? Which strategies do musicians implement in order to face these stereotypes? Based on a sociological perspective, we have implemented a qualitative method, directly interviewing the actors involved in this process. It is inferred that, despite the presence of positive representations, negative stereotypes may strongly affect the career of musicians, causing a direct impact that, according to them, derive in a poor appreciation of the trade. The consequences may go from the family´s imposition to study a better appreciated major to the dropout of the current studies. In certain situations, it may even have a direct effect on employment conditions.
Brecha educativa con las clases virtuales en México durante la pandemia del Covid-19.
Authors:   Centro de Investigaciones y Estudios Superiores en Antropología Social. (MÉXICO)., Gallegos de Dios Osbaldo Amauri
Published: July 2021

In “Education gap with virtual learning in Mexico during Covid-19 pandemic” we analyze the shutting down of schools around the world because of the coronavirus pandemic, the institutional projects of global and local virtual education, in universities of Mexico and Spain, and the teachers’ challenges in this period of distance and blended learning. Through an anthropological approach we analyze the school community’s sociocultural situation in Mexico during virtual education. Therefore, with this article we will understand that it is necessary to strength the state education system to battle education gap, educational lagging and ensure technology access to low-income students. Key words: Covid-19. Virtual education. Blended learning. Challenges. Institutional projects. Educational lagging. Low-income students. Education gap.
Eosinophilic granulomatosis with polyangiitis with an unusual presentation
Authors:   Nephrology Department – Centro Hospitalar e Universitário de Coimbra – Coimbra, Portugal, Nogueira Rui , Belmira Ana ,   Nephrology Department – Centro Hospitalar e Universitário de Coimbra – Coimbra, Portugal, Sousa Vitor ,   Nephrology Department – Centro Hospitalar e Universitário de Coimbra – Coimbra, Portugal,   Faculdade de Medicina – Universidade de Coimbra – Coimbra, Portugal, Alves Rui ,   Nephrology Department – Centro Hospitalar e Universitário de Coimbra – Coimbra, Portugal,   Faculdade de Medicina – Universidade de Coimbra – Coimbra, Portugal
Published: July 2021

Eosinophilic granulomatosis with polyangiitis is an ANCA vasculitis characterized by asthma, rhinosinusitis and peripheral eosinophilia. The kidney is infrequently involved, usually in the form of necrotizing crescentic glomerulonephritis. We present the case of a 60-year-old man who presented with painless sudden loss of visual acuity, purpuric exanthem in his legs, asthenia and myalgia. CT-scan ruled out acute vascular and intracranial space occupant lesions. Optical coherence tomography showed signs of left central retinal artery occlusion and perfusion deficits in the right arterial retinal blood supply. Complementary study showed prominent peripheral eosinophilia (24.500 cel/uL), increased serum IgE (1260U/L) and increased C-reactive protein (10.6mg/ dl). During admission, the patient presented with acute kidney failure (serum creatinine of 4.7mg/dl) and an exceptionally high p-ANCA MPO titer (>600U/L). Eosinophilic granulomatosis with polyangiitis was diagnosed and plasmapheresis, pulse steroid therapy and intravenous cyclophosphamide were provided. Kidney biopsy showed interstitial nephritis with high eosinophil content while the glomerulus was relatively spared, with only mild endocapillary proliferation. The patient didn’t require dialysis. Kidney function was normal at discharge, although the visual deficit did not improve.
Mourning the Bards: Interrogating the Contemporaneity of John Milton’s Lycidas and Pius Adebola Adesanmi.
Authors:   Adekunle Ajasin University, Nigeria, Ajidahun Clement
Published: July 2021

This paper examines John Milton’s ‘Lycidas’ in line with the traditional conventions for analyzing pastoral elegies which include the invocation of the muses, the presence of nature in the mourning process, the charging of the guardian spirits by the mourners of negligence, the mourning procession, the questions of justice, elaborate passage and the final consolation. The paper further interrogates the African concept of death and the mourning of the dead. It further discusses the semiotic codes of death and mourning in Africa. It also critically examines the contemporaneity ‘Lycidas’ and its place in the contemporary society by juxtaposing the mourning of the death of King Edward and Prof. Pius Adebola Adesanmi. The paper, which is dedicated to the sad memory of late Prof. Pius Adesanmi, quarries the similarities and the coincidences between the death and the mourning of King Edward and Prof. Pius Adesanmi who were both young and dynamic poets and scholars but who died prematurely while travelling. The paper shows that their death symbolizes the universality and the inevitability of death.
Efficacy of beta-blockers in the treatment of sepsis
Authors: Jin Peng , Zhao Tao , Wei Yueyue , Zhao Fang
Published: July 2021

This meta-analysis is to systematically evaluate the efficacy and safety of beta-blockers in the treatment of sepsis. A total of 17 articles that met the inclusion criteria were included, and 10,385 cases were obtained. The meta-analysis results showed that patients with sepsis with beta-blocker usage had a significantly lower 28-day mortality. The heart rate decreased over time in patients with sepsis using beta-blocker. Moreover, central venous blood oxygen saturation increased after 24, 48, 72 hours of treatment; lactic acid and cardiac troponin I decreased after 48, 72 hours of treatment; and tumor necrosis factor-α, interleukin-1β levels decreased significantly after 12, 24, 48, 72 hours of treatment (p<0.05).  In conclusion, beta-blockers reduce 28-day mortality and heart rate.
Bufalin inhibits the growth and epithelial to mesenchymal transition of human gastric cancer cells via modulation of MEK/ERK pathway
Authors: Zhou Yi , Wang Liguo , Lin Hui , Wang Yunxia , Hou Kezhu
Published: July 2021

This study was designed to evaluate the anti-cancer effects of bufalin against the human gastric cancer cells and unveil the underlying mechanism. The results showed that bufalin inhibited the proliferation and colony formation of the MGC-803 gastric cancer cells and exhibited an IC50 of 10 μM. These antiproliferative effects were found to be due to the induction of G2/M cell cycle arrest. The G2/M cell cycle arrest was also concomitant with inhibition of cdc2, cdc25 and cyclin B1. Furthermore, bufalin suppressed the epithelial-to-mesenchymal transition, migration, and invasion of the MGC-803 gastric cancer cells. The Western blot analysis revealed that bufalin exerted its effects via deactivation of EK/ERK signaling pathway. Taken together, these results suggest the potential of bufalin as the lead molecule for the development of chemotherapy for gastric cancer.
Free Radical Scavenging, Membrane Stabilizing and Thrombolytic Potentials of the Leaves of Quisqualis indica (L.)
Authors: Ahmed Farhana , Aktar Fahima , Rashid Mohammad A , Rahman Mohammad Sharifur
Published: July 2021

Bangladesh is a land of thousands of plants which might provide a scope to obtain therapeutically important natural drugs. Systematic screening of plants is very vital to fulfill this goal. Quisqualis indica (L.) is a vine and it belongs to the Combretaceae family. It grows all over the Bangladesh. It has some local uses to treat headache, skin disease, diarrhea, fever, cough, etc. In order to assess its biological potential, the leaves of the plant were collected and subjected to methanol extraction followed by fractionating into petroleum ether, carbon tetrachloride, chloroform and aqueous soluble materials. Primary free radical scavenging power of the extractives was evaluated using the radicals generated by DPPH and H2O2. Methanol crude extract as well as aqueous and chloroform fractions showed noticeable radical scavenging potential. Besides, these extracts had higher level of phenolics. The membrane stabilizing potential of the extractives was estimated based on the prevention of hemolysis of RBC prompted by hypotonic solution as well as heat. The aqueous fraction showed the highest level of membrane stabilizing potential indicating its primary anti-inflammatory ability. The extractives were also subjected to thrombolytic study. Mild thrombolytic ability was displayed by them compared to the standard. Further studies are required to explore bioactive compounds.
Bangladesh Pharmaceutical Journal 24(2): 99-104, 2021
Efektifitas Regulasi & Pengelolaan Infaq, Sedekah dan Dana Sosial Keagamaan
Authors: Mushthofa Abd. Halim , Wicaksono Ammar Kukuh
Published: July 2021

Warga jamiyah Nahdlatul Ulama (NU) termasuk di Kota Kediri tergolong cukup besar bahkan terbesar. Kondidi seperti ini tentunya menjadi peluang besar terhimpunnya dana bagi gerakan pengumpulan infaq, sedekh dan dana sosial keagamaan lainnya. Akan tetapi besarnya jumlah warga NU belum tentu dibarengi dengan besarnya pendapatan hasil penngumpulannya. Hal ini dapat dilihat dari misalnya laporan akhir tahun 2019 masih berkisar puluhan juta belum ratusan juta rupiah. Realitas seperti itu menunjukkan adanya masalah yang perlu untuk dikaji dan diteliti problem utamanya dan dicari solusinya. Maka dengan pendekatan tertentu penelitian perlu dilakukan yang kesimpulannya bisa dijadikan bahan pertimbangan dan kajian selanjutnya. Salah satu problemnya adalah persoalan efektifitas, baik efektifitas lembaga pengelola maupun efektifitas regulasinya. Sebuah aturan bisa dikatakan efektif dan rasional manakala bisa dan mampu menumbuhkan kesadaran banyak warga, demikian juga pengelolaan sesuatu kegiatan bisa disebut efektif manakala banyak orang dan banyak pihak dapat merasakan manfaatnya. Selain problem utama ada problem-problem hulu yang mendahuluinya semisal kondisi perekonomian warga, keterampilan dan profesionalitas pengelola, kesadaran dan kepercayaan mereka yang mampu, sosialisasi peraturan perundang-undangannya. Problem hulu ini jelas akan mempengaruhi efektifitas regulasi dan pengelolaannya, untuk itu solusi yang ditawarkan antara lain pengadaan training pengelola atau madrasah amil untuk menjadi lebih profesional dan terpercaya, keteladanan para tokoh-tokohnya disamping peningkatan jaringan komunikasi dengan berbagai pihak termasuk pihak pemerintah.
Kompleksitas Pembiayaan Ijarah Multijasa Dalam Fatwa Dewan Syariâ€™ah Nasional Nomor 44 Tahun 2004 Perspektif fiqh muamalah maliyyah
Authors: Jamaluddin  , Nawawie A. Hasyim
Published: July 2021

Sistem ekonomi syariah (keuangan syariah) tumbuh dan berkembang di berbagai negara, baik di kawasan negara yang mayoritas penduduknya muslim maupun muslimnya minoritas. Sistem ekonomi syariah (keuangan syariah) tidak hanya dianggap sebagai bagian dari ajaran islam, tetapi pandangan dan sikap hidup yang halal (transaksi yang dilarang), dalam rangka terbentuknya kesejahteraan umat. Persepsi masyarakat tentang ekonomi syariah (keuangan syariah) sesungguhnya terdiri dari 3 (tiga) variabel, yaitu 1) persepsi tentang akad multijasa yang berkaitan dengan bagi hasil bank, 2) sistem fiqh muamalah maliyyah yang berkaitan dengan bagi hasil bank, 3) produk bank syariâ€™ah itu sendiri. Penelitian ini bersifat kuantitatif dengan desain paradigma positivistik. Dalam tulisan ini dilakukan dengan menggunakan teknik studi referensi. Untuk itu peneliti mengambil referensi sebanyak kurang lebih 20 (dua puluh) buku (kitab) yang ada korelasinya dengan tulisan ini. Temuan tulisan ini menunjukkan bahwa pertama, persepsi tentang menggunakan produk bank syariah (akad ijrah multujasa), Kedua, sistem menggunakan produk perbankan syariah. Ketiga, produk bank syariah tidak berpengaruh terhadap minat masyarakat yang menggunakan produk perbankan syariah, akad ijarah multujasa perspektif fiqh muamalah maliyyah.
Pengaruh Capital Adequacy Ratio (CAR), Non Performing Loan (NPL), dan Loan to Deposit Ratio (LDR) Terhadap Return On Asset (ROA) Pada PT Bank Muamalat Indonesia
Authors: Nurfitriani Ika
Published: July 2021

Penilaian tingkat kesehatan Bank Umum Syariah dan Unit Usaha Syariah secara konsolidasi mencangkup penilaian terhadap beberapa factor seperti: Profil resiko, Good Corporate Govermance, Rentabilitas dan permodalan. Return On Asset (ROA) adalah salah satu rasio yang digunakan untuk mengukur kemampuan manajemen bank dalam memperoleh keuntungan secara keseluruhan, keuntungan yang diperolah perusahaan dapat menutup kemungkinan kerugian didalam kegiatan perkreditan dan perdagangan surat-surat berharga. Penilaian parameter ROA dapat menggunakan beberapa variabel diantaranya CAR, NPL dan LDR. Penelitian ini merupakan penelitian kuantitatif, dengan menggunakan rasio keuangan berupa CAR, NPL, dan LDR untuk mengetahui nilai ROA Bank Muamalat Indonesia, lalu dilanjutkan dengan uji One-Sample Kolmogorov-Smirnov Test dapat diketahui bahwa seluruh data yang digunakan pada penelitian ini berdistribusi normal. Sampel yang digunakan adalah laporan keuangan bulanan Bank Muamalat Indonesia periode Januari 2011 hingga Desember 2016, diperoleh sampel 70 sampel dengan menggunakan teknik purposive sampling. Hasil Uji Parsial pada penelitian menunjukkan bahwa CAR dan NPL berpengaruh positif terhadap ROA, sedangkan LDR tidak berpengaruh terhadap ROA dengan taraf signifikansi 0.002 serta prosentasi sebesar 58%.
Do STAD Learning Method Can Improve Students' Learning Outcomes on Social Science?
Authors: Anam Fatkul , A’yun Dhana Qurrota , Asitah Nur , Purnomo Agung , Laili Muawwinatul
Published: July 2021

Some students in elementary schools face some problems related to the students’ learning focus and interest in a social science subject. The Student Teams Achievement Divisions (STAD) of the cooperative learning model on educational management divides students into small teams to discuss and help each other. This study purposes to improve elementary school students’ learning outcomes focus on social science subjects using the STAD learning method. The implementation of the STAD learning method in this research is based on the Classroom Action Research model which was developed by Kurt Lewin. This model involves four stages, namely; planning, acting, observing, and reflecting. The result of this study proves that the applying of the STAD learning method on social science subjects in fourth-grade elementary students can improve the students’ learning outcomes, role, enthusiasm, and cooperation between others in the learning process. It can be seen from the increase of students’ learning outcomes completeness reach up to 80,9%.
Pengembangan Kurikulum Pendidikan Islam di Era New Normal
Authors: Ramadhan Ossi Marga , Hermawan Acep Heris , Erihadiana Mohamad
Published: July 2021

This study intends to analyze the Islamic education curriculum development in the New Normal era, using a qualitative approach to library research. Researchers found that what must pursue the Islamic education curriculum in the New Normal period by integrating content, preparing a systematic learning concept and good training in terms of the use of technology so that it is accustomed to carrying out the learning process online. One of the ideal educational strategies during this pandemic is to explore the government's provisions by using an agreed application. There are two crucial component elements in the implementation of the learning process activities; namely, students and educators must be given training related to technology media to know the direction of learning so that they avoid mistakes that will become a problem. Meanwhile, students carry out learning at home with the help of parents who supervise every activity during the online learning process so that learning misunderstandings do not occur during a pandemic.
Media Sosial Sebagai Sarana Membentuk Identitas Diri Mahasiswa Universitas Airlangga Surabaya
Authors: Zakirah Dinda Marta Almas
Published: July 2021

Currently, technology does not only provide ease for the users but also creates some social media that makes the users be able communicating from distances. Social media can also be used to share any photos and videos such as the one that is being the favorite of its users namely instagram. However, instagram is no longer functions for photo and video sharing but to form self-image.Many youth try to build up their self-images on instagram and many of them are students of Airlangga University. Therefore, this research is conducted to know how students of Airlangga University form their self-images on instagram.

This research uses qualitative approach. The data collection technique in this research is in-depth interview and field observation.The theories used in this research are hiperrealitas Jean Baudrillard andNet Generation Theoryfrom Don Tapscott. Then, the sampling uses purposive method. The subjects of this research are 8 students consisting female and male students of Airlangga Universitywho are included in two instagram accounts namely @satuunair and @unairhitspeople.

The result of this research reveals that students of UNAIR form their self-images on instagram. They do it by editing the photo they will share on instagram, also the selection of location and angle for a photo. Besides, forming self-identity on social media does not fully give negative effect.By the internet and smart phones, the intensity to use smart phones gets bigger than before the internet existed. Hence, it proofs that they get positive beneficial impact.

Keywords: University student, social media, instagram, self-image, net generation.
Cost per responder for upadacitinib vs abatacept in patients with moderate-to-severe Rheumatoid Arthritis in Italy
Authors: Caporali Roberto , Ravasio Roberto , Raimondo Paola , Salaffi Fausto
Published: July 2021

Purpose: The objective of this economic evaluation was to compare the cost per responder between upadacitinib and abatacept (intravenous [iv] or subcutaneous [sc]) in patients with moderate-to-severe Rheumatoid Arthritis (RA) in Italy.

Methods: The clinical efficacy was assessed based on SELECT-CHOICE study results. The clinical efficacy of upadacitinib and abatacept (iv or sc) was measured by Clinical Remission (CR), Low Disease Activity (LDA) and American College of Rheumatology response (ACR20, 50 and 70). The treatment cost was based on the number of administrations dispensed at 12 or 24 weeks. The cost per responder was adopted as a cost-effectiveness indicator.

Results: Independent of the clinical efficacy measure used and the duration of treatment considered, the cost per responder was consistently lower for upadacitinib compared to abatacept (iv or sc) across all clinical measures. For example, considering the CR at 24 weeks, the cost per responder for upadacitinib was € 9,417 compared to € 17,817 for abatacept sc or to € 23,110 for abatacept iv. The differences in the cost per responder between upadacitinib and abatacept (iv or sc) increased when higher ACR response levels were considered.

Conclusions: These results suggested that upadacitinib is a cost-effectiveness option compared to abatacept (iv or sc) from the perspective of the Italian National Health Service in patients with moderate-to-severe Rheumatoid Arthritis in Italy.
Can daily consumption of a nephroprotective homeopathic product protect the kidneys from gentamicin toxicity?
Authors: Machado Giovana Carolina , Glombowsky Patricia , Galli Gabriela Miotto , Bissacotti Bianca Fagan , Copetti Priscila Marquezan , Druzian Leticia , Morsch Vera Maria , Mendes Ricardo Evandro , Silva Aleksandro Schafer da
Published: July 2021

The objective of this work was to determine whether preventive consumption of a homeopathic product via drinking water would protect mouse kidneys from a challenge with the nephrotoxic antibiotic gentamicin. We used 40 Swiss mice divided into four groups with ten animals each. The homeopathic product was supplied through water for 30 days in a preventive manner and gentamicin for 10 days to induce an experimental renal failure. The groups were as follows: Negative-CT (homeopathic and gentamicin was not provided), Positive-CT (did not receive homeopathic, but received gentamicin 40 mg/kg), T2 (received 0.002 ml of the product per animal/day, and received gentamicin 40 mg/kg), and T4 (0.004 ml of the product per animal/day and received gentamicin 40 mg/kg). On days 12 and 20, blood and tissue samples were collected from five animals in each group. No histopathological lesions were found in mouse kidneys. However, levels of thiobarbituric acid reactive substances, reactive oxygen species, and nitrite/nitrate ratios in the kidney of the Positive-CT group were higher compared to the other groups. As for glutathione S-transferase, on the 20th day, the groups that used the homeopathic product (T2 and T4) had higher activities than the positive TC. Therefore, the results suggest that prophylactic consumption of the hepatoprotective homeopathic product can decrease lipid peroxidation, nitrous stress, and oxidative stress at the renal level when consecutive doses of gentamicin induce insufficiency.
Avaliação do grau de prontidão em gerenciamento de portfólio de projetos: Estudo de caso da Secretaria de Segurança Pública do Estado da Bahia - Brasil
Authors: Oliveira Roberto Otuzi de , Silva Rodrigo Florêncio da
Published: July 2021

Este artigo analisa o grau de prontidão em gerenciamento de portfólio de projetos na Secretaria de Segurança Pública do Estado da Bahia, Brasil. O estudo utilizou o modelo PPM Ready (Project portfolio management ready) proposto por Norberto Almeida. Esse modelo analisa o grau de prontidão em gerenciamento de portfólio de projetos por meio de três passos, avaliando quatro pilares. As organizações são estruturadas pelas suas operações contínuas e por seus projetos, que são os meios pelos quais uma ideia é transformada em produto, serviço ou solução tangível. Mas o nível que utilizam e têm conhecimento do gerenciamento de portfólio de projetos variam. Um maior amadurecimento em gerenciamento de portfólio de projetos proporciona custos menores que os previstos, prazos menores com sucesso no encerramento do projeto. Quanto mais madura for uma organização, maior será a taxa de sucesso de seus projetos. Para alcançar a maturidade, existe um esforço contínuo que geralmente leva alguns anos até que os resultados alcançados reflitam uma taxa maior de sucesso nos resultados dos projetos. Vários modelos de avaliação de maturidade em gerenciamento de projetos foram criados para verificar o quanto as organizações estão fazendo para melhorar seu desempenho. A maioria deles avalia o nível de gerenciamento de projetos e há falta dos outros níveis, como o gerenciamento de portfólio. A avaliação da maturidade em organizações que implementaram o gerenciamento de portfólio é um tópico bastante recente e não tem sido discutido na academia em profundidade, principalmente no setor público.
Adesão de dispositivos ortodônticos utilizando adesivo hidrofílico Transbond™ Plus Color Change e adesivos à base de Cianoacrilato para tração ortodôntica de dentes impactados
Authors: Medeiros Ilana Nóbrega de , Linhares Layara Maria Vieira , Nogueira Paula Lima , Dantas Maria Vitoria Oliveira , Santana Maria Tays Pereira , Rocha Julierme Ferreira , Figueiredo Camila Helena Machado da Costa , Guenes Gymenna Maria Tenório , Alves Maria Angélica Sátyro Gomes , Rosendo Rosana Araújo , Penha Elizandra Silva da , Oliveira Filho Abrahão Alves de , Medeiros Luanna Abílio Diniz Melquiades de
Published: July 2021

Tendo em vista a problemática existente nos procedimentos de tracionamento ortodôntico de dentes impactados quanto a fixação e manutenção das peças ortodônticas ao elemento dentário, tendo em vista as peculiaridades do meio bucal, considerando isso, o objetivo desse estudo foi avaliar, por meio da revisão da literatura, a adesão de dispositivos ortodônticos utilizando adesivo hidrofílico Transbond™ Plus Color Change 3M e adesivos à base de cianoacrilato. No presente trabalho foi utilizado o método de revisão de literatura com o tema Adesão de dispositivos ortodônticos utilizando adesivo hidrofílico Transbond™ Plus Color Change 3M e adesivos à base de cianoacrilato.  Assim sendo, foi realizada uma busca nas bases de dados MEDLINE, Portal BVS, Scielo e LILACS, entre os anos de 2012 e 2021 sendo em português, inglês ou espanhol. Logos após a aplicação dos critérios de inclusão e exclusão, doze artigos foram selecionados. A partir disso, pode-se concluir que a força de adesão de dispositivos ortodônticos utilizando adesivo hidrofílico Transbond™ Plus Color Change 3M e adesivos à base de cianoacrilato variaram nos estudos, o que é possível ser justificado pelas diferenças metodológicas observadas nestes.
Piso Pegajoso, Teto de Vidro e Abelha Rainha: a tríplice barreira imposta pela conomia sexista
Authors: Nunes Kesia Kiss , Lima Angelita Pereira de
Published: July 2021

O capitalismo possui suas bases fundadas na economia sexista, na qual a mulher representa meio para aquisição de lucro fácil. Partindo dessa premissa, o presente trabalho visa, por meio de pesquisa bibliográfica, estudar o “piso pegajoso”; o “teto de vidro” e o fenômeno “abelha rainha” como tríplice barreira encontrada pelas mulheres para alcançar cargos de comando, bem como as consequências desse modelo econômico.
Probióticos na modulação intestinal como adjuvante no tratamento de sinais e sintomas de depressão
Authors: Oliveira Erick Michell Bezerra , Moura Manoel Augusto de , Assunção Luanna da Silva de , Luz Aline Cristina Ribeiro da , Atan Adyelle Karoline , Matos Rubenilson Luna , Silva Julianne de Area Leão Pereira da , Moreira Thiago Henrique Gonçalves , Cardoso Jonas Alves , Assunção Flávio Bruno Rodrigues de , Conceição Domingas Marlyene Silva , Santos Francisco de Assis Viana dos , Galvão Géofrey Henrick Silva , Bezerra Hernandys Ribeiro , Sampaio Nathália Cássia Martins
Published: July 2021

Objetivo: Este estudo teve como objetivo investigar se os probióticos melhoraram sintomas de depressão e ansiedade em avaliadas por diferentes escalas psicométricas. Metodologia: O presente estudo trata-se de uma revisão bibliográfica do tipo integrativa, realizada por meio de um levantamento de literatura pesquisa bibliográfica no PubMed combinando os termos "Probióticos", "Modulação Intestinal" e "Depressão" para identificar os estudos de ensaios clínicos em humanos que investigaram as relações entre aspectos depressivos, ansiosos e a microbiota. Resultados: Os dados foram extraídos de 12 estudos de ensaios clínicos (922 humanos), randomizado, controlados, duplo-cego. No contexto avaliado, probióticos reduziram pontuação nas diferentes escalas psicométricas reduzindo o comportamento semelhante a ansiedade e depressivo. Análises de análises em nível de espécie probiótica, identificaram subespécies do gênero Lactobacillus e Bifidobacterium a capacidade de atividade ansiolítica. Melhoras ⩾60% em escalas avaliativas foram demonstradas com suplementação de probióticos e até mesmo melhoras na qualidade de vida em indivíduos com doenças inflamatórias intestinais. Conclusão: A microbiota foi alçada a um alvo potencial para o tratamento de transtornos psiquiátricos e antidepressivos. A depressão é um desafio para a saúde global, pois demanda intervenções multidisciplinar já que está doença se caracteriza como uma desordem metabólica cerebral e os probióticos desempenhariam uma ação essencial sobre o estado de saúde e doença do indivíduo.
Oral health status and dental care for hospitalized patients with facial fractures
Authors: Andrade Ana Karisse de Carvalho , Mendonça Maria Patrícia Rogério de , Pinto Clarice Maia Soares de Alcântara , Mello Manoel de Jesus Rodrigues , Benevides Breno Souza , Silva Paulo Goberlânio de Barros , Carvalho Abrahão Cavalcante Gomes de Souza
Published: July 2021

Objective: to analyze the oral health profile of inpatients victims of oral and maxillofacial trauma at the Institute Dr. José Frota Hospital, Ceará, Brazil. Methodology: a study carried out in 2020 started with an examination of the oral cavity at the bedside, application of the DMFT and The Bedside Oral Exam indexes, together with the survey of dental needs and application of the Oral Health Impact Profile Scale (OHIP-14), relating the findings, applying average, standard deviation and calculating Cronbach's alpha coefficient and Spearman's correlation for the OHIP-14 finding. Results: We evaluated 78 patients, mostly male (88%), with a mean age of 32.72 ± 11.63 years old, with hypertension being the most prevalent comorbidity. Besides, 60% of the sample had a fracture in the lower third of the face. The average number of decayed teeth per patient was 5.69. About 62.82% had poor oral health, seen from generalized biofilm and swollen gums. Low-Level Laser therapy was indicated for 94.8% of the sample, periodontal treatment in 58.9%, restorative therapy in 69.2%, and surgical in 42.3%. Regarding the OHIP-14 questionnaire, facial trauma negatively impacted the participants' quality of life, especially in dimensions related to pain. Conclusion: there was a significant prevalence of oral diseases, such as gingivitis and dental caries, which justifies the need for dental intervention before the maxillofacial surgical approach.
Atuação da enfermagem na campanha de vacinação contra a COVID-19 em um Centro Universitário em Belém-PA
Authors: Cunha Amanda Guimarães , Carvalho Daylane Pereira de , Neri Débora Talitha , Passinho Andréa Moreira , Leão Bianca Brabo de , Castro Anna Carolina Paixão , Souto Dirce Helena da Silva , Carvalho Pedro Henrique Carrias de , Neves Maria Luciana da Silva , Sarges João de Cássio Santana de , Ribeiro Thais Silva , Lima Joyce Souza , Furtado Arielly Rosa Dantas , Chaves Thiago André de Souza , Menezes Aline Cardoso de , Santos Leandro Costa dos , Portilho Danielle Cardoso
Published: July 2021

O Brasil possui o maior programa de vacinação do mundo, sendo reconhecido nacional e internacionalmente. O Programa Nacional de Imunizações, atende atualmente 212 milhões de pessoas. Criado em 18 de setembro de 1973, é um patrimônio do estado brasileiro, mantido pelo comprometimento e dedicação de profissionais de saúde, gestores e de toda população. Diante da pandemia da COVID-19 a enfermagem ocupou a linha de frente, em termos de visibilidade de sua atuação, dedicação e competência. O resultado foi o reconhecimento de sua importância para além dos muros dos ambientes de cuidado. O objetivo deste estudo é relatar a atuação da equipe de enfermagem na campanha de vacinação contra a COVID-19 em um Centro Universitário. Trata-se de um estudo descritivo, com abordagem qualitativa, do tipo relato de experiência, que se deu a partir da vivência de acadêmicos de enfermagem e enfermeiros. Considerando o elevado quantitativo de usuários idosos a serem imunizados, estes que de acordo com o Plano Municipal de Operacionalização da Vacinação contra COVID-19, fazem parte do público alvo da 1° fase da vacinação, se fazia necessário um quantitativo de voluntários da enfermagem proporcional a demanda de usuários. A partir do exposto, reitera-se a importância da atuação da equipe de enfermagem nas salas de vacina, e o quanto estes profissionais são capacitados para atuarem no atual cenário pandêmico, mesmo alguns ainda na vida acadêmica, o compromisso e a competência, que foram adquiridos ao longo de anos de estudo e aprendizado.
Inclusão no Ensino Superior: Percepções de docentes de uma universidade pública da região norte do Brasil
Authors: Teixeira Leticia Oliveira , Guimarães Beatriz de Araujo , Pereira Rosamaria Reo , Faciola Rosana Assef
Published: July 2021

O presente estudo analisou a percepção dos docentes de uma faculdade da Universidade Federal do Pará acerca da formação docente e prática pedagógica na perspectiva da Educação Inclusiva. 18 docentes foram entrevistados, sendo um professor de Língua Espanhola, três professores de Língua Francesa, dois de Língua Alemã e 11 de Língua Inglesa. Adotou-se uma pesquisa de caráter exploratório e descritivo com dados qualitativos e quantitativos. Como instrumento de pesquisa foram utilizados um questionário sociodemográfico e um questionário com perguntas pré-definidas aplicados por meio do Google Formulários. Os depoimentos foram agrupados nas seguintes dimensões de análise: a) Percepção sobre a formação docente; b) Percepção sobre a importância das disciplinas de inclusão nos currículos das licenciaturas; c) Percepção acerca das experiências com alunos com deficiência; e d) Percepção sobre o papel da UFPA no apoio ao docente. Os resultados revelaram que a maioria dos docentes não possuía formação inicial ou continuada ou capacitação para lidar com alunos com deficiência em sala de aula, porém a maioria declarou estar motivados e dispostos em aperfeiçoar seus conhecimentos sobre o assunto. Há necessidade de incluir disciplinas sobre Educação Inclusiva na formação inicial dos futuros professores. Os cursos oferecidos aos docentes pela instituição ainda não são o suficiente para garantir a formação continuada, pois encontrou-se problemas de comunicação ou de falta de motivação por parte de alguns professores. Concluiu-se que os participantes estão cientes das suas dificuldades em relação a sua prática pedagógica, da importância da inclusão e da necessidade de políticas afirmativas inclusivas.
Ações de prevenção e controle do tabagismo no ambiente escolar: Relato de experiência
Authors: Souza Raniel Rodrigues , Pereira Agliely Gomes , Almeida Marcus Vinícius de Arruda , Rodrigues Yasmin Luana Andrade , Ribeiro Junior Orácio Carvalho , Albarado Kaio Vinícius Paiva , Ramos Semírames Cartonilho de Souza , Araújo Tatiane Silva de , Martins Tayane Moura , Santos Rosane Silva dos , Ferreira Suzana Maria da Silva , Figueiredo Aline Verçosa de , Cunha William Cardoso da
Published: July 2021

Objetivo: Relatar as ações educativas, realizadas com escolares adolescentes, sobre os efeitos nocivos do tabagismo e a importância de não iniciar e, quando for o caso, de parar com o hábito de fumar. Método:  Trata-se de um relato de experiência das atividades integradas em saúde, realizadas por estudantes do curso de enfermagem de uma instituição de ensino superior pública situada na Região do Xingu, em novembro de 2019. As ações educativas foram balizadas pela metodologia da problematização, tendo como operar prático o Arco de Maguerez. Resultados: Após o contato inicial com o público-alvo para verificar seus conhecimentos prévios e carências sobre a temática, os acadêmicos elaboraram estratégias para promover o momento educativo que foi operacionalizado por meio de uma vídeo-aula projetada para os escolares sobre os componentes do cigarro. Além disso, foi realizado um quiz por meio do aplicativo plickers no qual os alunos puderam interagir com os acadêmicos, esclarecendo suas dúvidas sobre a temática abordada. Após isso, foram realizadas duas demonstrações práticas em ambiente aberto, com simuladores artesanais, desenvolvidos pelos próprios acadêmicos, sobre os efeitos deletérios do uso de cigarros para o pulmão. Todas as atividades tiveram anuência da gestão escolar e foram desenvolvidas sob supervisão de um docente. Considerações Finais: As atividades educativas foram de extrema importância, pois delinearam-se a partir das necessidades de conhecimentos dos escolares, sanando suas dúvidas sobre a temática. Para os graduandos, a experiência permitiu o desenvolvimento do currículo integrado do curso de enfermagem, além de qualificar o processo de formação sobre a temática.
Avaliação toxicológica da 4-hidroxicumarina: (Anti) Mutagenicidade, estudos de toxicidade e antioxidantes
Authors: Cruz Luisa Ferreira da , Santos Cicero Gonzaga , Gonçalves Thais Paula Rodrigues , Marena Gabriel Davi , Souza Israel Lucas Antunes , Lima Luciana Alves Rodrigues dos Santos , Chequer Farah Maria Drumond , Pinto Flavia Carmo Horta , Nogueira Flavia Aparecida Resende , Araujo Marcelo Gonzaga de Freitas
Published: July 2021

A 4-hidroxicumarina (4H) é um composto fenólico natural e sintético que apresenta atributos importantes, incluindo propriedades anti-HIV, antitumoral e anticoagulante. Considerando suas importantes atividades biológicas e a utilização da 4H, o objetivo do presente estudo foi investigar as atividades tóxica, mutagênica, antimutagênica e antioxidante da 4H, obtido comercialmente, em experimentos in vivo e in vitro. Os efeitos da administração oral aguda na dose de 200 mg / kg de 4H foram investigados pela triagem hipocrática em animais. O ensaio de micronúcleo em sangue periférico e o teste de Ames foram utilizados para análise de mutagenicidade, enquanto a antimutagenicidade foi testada contra a ciclofosfamida também pelo ensaio de micronúcleo in vivo. Para todos os testes in vivo foram utilizados camundongos Swiss. A atividade antioxidante foi determinada pela capacidade da amostra 4H de sequestrar o radical estável 2,2-difenil-1-picrilhidrazil (DPPH). Os resultados mostraram que o 4H não induziu alterações no comportamento ou na histologia dos animais tratados nem na atividade mutagênica (gênica ou cromossômica). Por outro lado, exibiu efeito protetor contra ciclofosfamida e potencial antioxidante. A 4H é amplamente utilizada clinicamente como uma molécula precursora na síntese de fármacos anticoagulantes sintéticos. Portanto, os resultados obtidos são de extrema importância, pois demonstram ausência de potencial mutagênico e proteção contra danos cromossômicos.
Formulação e caracterização físico-química de geleias convencional e dietética de mandacaru e umbu
Authors: Santos Neto João Paixão dos , Silva Lucas Afonso Sotero Gouveia da , Gatti Victória Carolline do Moraes , Beirão Antonio Thiago Madeira , Silva Claudete Rosa da , Oliveira Job Teixeira de , Silva Katiane Pereira da , Carvalho Fábio Israel Martins , Silva Priscilla Andrade , Santana Maria Cecília Castelo Branco de
Published: July 2021

A geleia é considerada um produto de destaque em escala industrial, devido à boa aceitação pelos consumidores. O objetivo deste estudo foi desenvolver geleia convencional e dietética mista de umbu e mandacaru. As geleias foram elaboradas através da formulação padrão e dietética, uma com sacarose e a outra com xilitol, polpa de umbu e de mandacaru, pectina cítrica e ácido cítrico. Após 30 dias de armazenamento em temperatura ambiente foram avaliados os parâmetros físico-químicos. Os resultados obtidos foram submetidos à análise de variância pelo software Agroestat. Os valores médios das características físico-químicas dos frutos de umbu e mandacaru obtiveram valores satisfatórios para produção de geleia. A geleia convencional se enquadra nos aspectos da legislação em vigor. A geleia dietética não atendeu o padrão de identidade e qualidade e apresentou a presença de sinérese.