bluuebunny/crossref_metadata_2025 huggingface dataset:
Crystallisation, Preliminary X-Ray Analysis and Secondary Structure Detennination of Formamidase from Methyloplzilus methylotrophus
Authors: O'Hara Bernard P. , Wilson Stuart A. , Wyborn Neil W. , Jones Colin   W. , Pearl Laurence H.
Published: April 2022

Metlrylophilus methylotroplzus expresses a specific fonnamidase (formamide amidohydrolase; E.C. 3.5 . 1.49) . The enzyme has a calculated subunit molecular weight of 44kDa but is multimcric in solution. Forrnamidasc
crystallises in space group P21 with unit cell dimensions a= 112.4Å, b= 131.4Å, c= 128.9Å, β= 115.3°. The crystals Contain 6 or 8 molecules in the asymmetric unit and diffract beyond 2.5Å .
New Approaches and Advancements in Drug Development from Phenolic
P-coumaric Acid
Authors: Malik Neelam , Dhiman Priyanka
Published: April 2022

P-coumaric acid is a common dietary polyphenol present in fruits, vegetables, and cereals
in conjugated and free form. The toxicity profile of the drug is very low, and it exhibits many pharmacological
actions (antihypertensive, anti-inflammatory, anticancer, antimicrobial activity, antidiabetic,
anticancer, and antioxidant effect). P-coumaric acid also acts as a free radical scavenger and
inhibits various enzymes, which generate free radicals. It is also used as the raw material for the
preparation of preservatives, vanillin, sports foods, skin defense agents, and as a cross-linker for the
formation of edible films and food gels. The current study is based upon biological effectiveness,
molecular docking, SAR, sources of p-coumaric acid, and related derivatives.
An Improved Synthesis of Glucuronide Metabolites of Hindered Phenolic
Xenoestrogens
Authors: Sancéau Jean-Yves , Poirier Donald , Bélanger Patrick , Maltais René
Published: April 2022

Aim and Objective:

The syntheses of glucuronide metabolites of phenolic xenoestrogens triclosan and 2-phenylphenol, namely triclosan-O-glucuronide (TCS-G; 1), and 2-phenylphenol-O-glucuronide (OPP-G; 2), were achieved for use as analytical standards.

Methods:

Under classical conditions previously reported for glucuronide synthesis, the final basic hy-drolysis of the peracylated ester intermediate leading to the free glucuronides is often a limiting step. Indeed, the presence of contaminating by-products resulting from ester elimination has often been ob-served during this step. This is particularly relevant when the sugar unit is close to a crowded envi-ronment as for triclosan and 2-phenylphenol.

Results:

To circumvent these problems, we proposed mild conditions for the deprotection of peracety-lated glucuronate intermediates.

Conclusion:

A new methodology using a key imidate following a two-step protocol for acetates and methyl ester hydrolysis was successfully applied to the preparation of TCS-d3 (1) and OPP-G (2) as well as deuterated isotopomers TCS-d3-G (1-d3) and OPP-d5-G (2-d5).
A Strategic Investigation on Diabetic Nephropathy; Its Conceptual Model
and clinical Manifestations: A Review
Authors: Wal Pranay , Tyagi Sachin , Pal Rashmi Saxena , Yadav Anil , Jaiswal Riya
Published: April 2022

Diabetes is a major health issue for humans, and its complications can lead to a variety of health problems. Nephropathy has been recognised since the 1930s, when Kimmelstiel and Wilson first reported the characteristic nodular glomerulosclerosis lesions in diabetic kidneys. Diabetic nephropathy (DN), commonly known as diabetic kidney disease, is a condition in which diabetics have excessive quantities of urine albumin excretion, diabetic glomerular lesions, and a reduction in their glomerular filtration rate (GFR). Type 1 diabetes (autoimmune -cell destruction and absolute insulin insufficiency), type 2 diabetes (relative insulin deficit and resistance), and others are the three forms of diabetes (eg, pancreatic disease). Diabetes nephropathy is a leading cause of chronic kidney disease and end-stage renal failure around the world. Much research has been conducted in both basic science and clinical therapies to enhance understanding of the mechanism of diabetic nephropathy and to expand the available therapeutics. Diabetic nephropathy prevention continues to rely on screening for microalbuminuria and treating hyperglycemia. However, several studies suggest that managing diabetic kidney disease is more challenging. Despite comparable hyperglycemic management, some studies suggest that the incidence of renal problems varies by patient. As a result, there has been a great deal of interest in studying the inherent renal protective effect of various antihyperglycemic drugs. The goal of this study is to provide information about the diabetic kidney disease conceptual model, pathogenesis, screening, and diagnosis. It will also address the treatment and prevention of diabetic nephropathy, with a focus on comparing the mechanisms, safety profiles, and efficacy of different antihyperglycemic medications.
Industrial Doogh: Technological and Health Aspects
Authors: Sayevand Hamid Reza , Bakhtiary Farzaneh , Mollakhalili-Meybodi Neda , Mortazavian Amir M.
Published: April 2022

As a typical and ancient Iranian drink based on fermented milk, Doogh is normally
produced from yogurt, drinking water, salt, and flavoring agents on both traditional and industrial scales. Referring to the large production and consumption of Doogh in many countries and the
adoption of its Codex standard (2018), considering its technological and health (nutritional and
safety) aspects is of special importance. There is versatility and variety in ingredients, production
methods, and packaging of Doogh that can affect the physicochemical (i.e., physical, chemical,
and rheological) sensory, nutritional, and safety characteristics of the product. On the other hand,
its shelf life is regularly an extended shelf life (>2 months) which can be challenging from a
technological point of view. This article comprehensively reviews the technological and health
aspects of industrial Doogh.
Purified Stigmasterol Related Novel Phytosterol from Chrysopogon
zizanioides (L.) Roberty Root Extract Exhibits Strong Cholesterol Esterase
(CEase) and Diabetic Foot Ulcer (DFU) Causing Bacterial Pathogens Inhibitory
Properties
Authors: Sathishkumar Thiyagarajan , Arun Appakudal Venkataraman Venkatesh , Soundaram Rajendran , Kumaresan Kuppamuthu , Rapheal Vinohar Stephen , Thirugnanam Natarajan
Published: April 2022

Background:

Chrysopogon zizanioides Roberty. root extracts have documented amylase and α-glucosidase inhibition, hepatoprotection, antioxidant, antimicrobial, antihyperglycemic, antidepressant, and antitubercular properties, but lack ample reports on health care applications of purified phytoconstituents.

Objective:

To study the inhibitory properties of phytosterol eluate against cholesterol esterase (CEase) and diabetic foot ulcer (DFU) causing pathogens (clinical isolates).

Methods:

The shake flask method was adopted to extract the phytoconstituents and standard spectrophotometric assays were carried out to quantify phytosterol constituent and CEase inhibitory activity. Central composite design (CCD) based response surface methodology (RSM) was adopted to observe the improvement of phytosterol constituent and CEase inhibitory activity. Two dimensional preparative thin layer chromatography (2D PTLC) technique was executed to purify the phytosterol content and HRLC based APCI – Q-TOF/ MS2 analysis was done to predict the phytosterol structures. Standard disc assay was used to explore the inhibitory effect of extract and purified phytosterol content against DFU causing pathogens.

Results:

The crude extracts exhibited a moderate CEase inhibitory activity (Ethylacetate: 67 ± 3.2%) and appreciable phytosterol content (Acetone:11.24 ± 0.52 mg/g tissue). CCD based RSM has improved the CEase inhibitory activity (Ethylacetate: 96.56 ± 1.1%) as well as the phytosterol content (6.45 ± 0.5 mg/g tissue). The purified phytosterol fractionate (PTLC eluate) was found to contain stigmasterol related novel phytosterol and revealed a significant CEase inhibitory activity (81 ± 2.5 %; Ki: 54.89 µg) with mixed type inhibition.

Conclusion:

Both the extract and the PTLC eluate have recorded a substantial control over DFU causing bacterial pathogens.
Plumeria acuminata: A Systematic In Vivo Evaluation for its Antiovulatory
and Anti-implantation Features
Authors: Rabadia Jay P. , Desai Tushar R. , Thite Vihang S.
Published: April 2022

Background:

Fertility control becomes necessary for under-developed and developing nations
for the betterment of the economy, environment, and society. Plant Plumeria acuminata, “Temple
tree or Frangipani,” of the Apocynaceae family, has exhibited several activities similar to contraceptive
medicine and is widely distributed in India.

Objective:

Present investigation aimed to study the anti-ovulatory and anti-implantation activities of
ethanolic extract from P. acuminata leaves and roots in Wistar rats.

Methods:

Ethanolic extracts of P. acuminata leaves and roots were subjected to qualitative phytochemical
analysis and acute toxicity test. Immature female rats were used to explore anti-ovulatory
characteristics by administering HCG as a standard ovulation-inducing drug. Mated females were used
for exploring anti-implantation characteristics. Levonorgestrel and Ethinylestradiol were administered
as standard anti-implantation drugs. Morphological, hematological, hormonal, and histological examinations
were performed.

Results:

LD50 value, i.e., 2000 mg/kg from acute toxicity test, resulted in the selection of 100, 200,
and 400 mg/kg dose values for both leaf and root extracts. Treatment with these brought ~2-54%, ~5-
48%, and ~1-68% changes respectively in the hormonal, growth factors’ and cytokines’ profiles. Ovarian
histology revealed restricted follicle maturation and ovulation, whereas uterine histology unveiled
a ~5-28% decrease in the endometrium thickness, making it unreceptive for implantation after treatment
with PAL and PAR extracts.

Conclusion:

Anti-ovulatory and anti-implantation results obtained here can be attributed to the presence
of plumericin, sterol, as well as triterpene groups of phytochemicals from ethanolic extracts of
leaves and roots, making them potent contestants for studies on future contraceptive medicines.
Impact of Educational Intervention on the Knowledge, Attitude, and Practice
of Pharmacovigilance Among Nurses at a Tertiary Care Public Hospital
Authors: Munshi Renuka , Maurya Miteshkumar
Published: April 2022

Background:

Nursing students and employees remain the first point of contact in case a
patient develops an adverse drug reaction in hospital settings. Thus, it is important for nurses to
understand the importance of pharmacovigilance activity and implement the same in their practice.
They can also contribute to drug safety by reducing medication errors and adverse drug reaction
reporting.

Methods:

After ethics approval, an observational questionnaire-based study was conducted in 2017
that involved nursing students and nursing employees (N=390) to assess their baseline knowledge,
attitude, and practice toward pharmacovigilance. Participants who consented were enrolled and a
pre-training survey was conducted. Pharmacovigilance sensitization/ training sessions were conducted
in the same year after getting their baseline data. Three years later in 2021, the same questionnaire
was distributed to a subset of nursing students and employees (N=299) to analyze any
change in their knowledge, attitude, and practice towards the pharmacovigilance activity as a posttest.
Pre and post sensitization session questionnaire-based survey data was analyzed to confirm the
long-term impact of conducting such pharmacovigilance awareness training.

Results:

The nurses’ overall performance before and after training in each of the domains of
knowledge, attitude and practice were 17.53%, 72.86%, 39.69% in the pretest group, respectively,
and post test scores were 30.77%, OR-3.04, p=0.0 (Knowledge), 85.92%, OR-0.14, p=0.0 (Attitude)
and 37.21%, OR-0.08, p=0.08 (Practice) in the corresponding domain. Overall, there was a
declining trend in the practice domain of the nurses response between the pre-test and post intervention
groups however this decline was not statistically significant (p=0.08).

Conclusion:

Pharmacovigilance awareness training and sensitization programs had an impact on
the knowledge and attitude of nurses but there is a need to ensure that it is implemented in clinical
practice.
Is Corneal Collagen Cross-Linking Beneficial as an Adjunct to the Conventional Treatment of Bacterial Keratitis?
Authors: Mahmoud Amira Asem , Abd-Rahman Mohamed Saad , Mohamed Tarek Ahmed , El-Sebaity Dalia Mohamed
Published: April 2022

Background:

To evaluate the therapeutic effects of corneal collagen cross-linking CXL as an adjuvant to standard antimicrobial agents in the treatment of bacterial keratitis when compared to treatment with antimicrobial agents alone.

Methods:

This prospective comparative interventional study included 20 eyes of 20 patients with clinical and laboratory evidence of bacterial keratitis who attended the Outpatient Cornea Unit, Ophthalmology Department, Faculty of Medicine in Assiut University Hospital, Assiut, between January 2019 and December 2020.Patients were divided into two groups: group A, treated with CXL using the Dresden Protocol at the EL-Nour Eye Centre, and group B treated with antibiotics alone.

Results:

Group A had ten patients in the age range of 20-80 years (mean age 49.2 years), while that of group B (ten patients) was 19 -70 years (mean age 47.3 years).

The ulcer sizes started to decrease significantly from week 2 in group A to week 3 in group B. The epithelization time was significantly different between the two treatment groups as reepithelization in 60% of group A cases started at week two, while it began at week three in group B. There was no significant difference in the V/A between the two groups after treatment.

Conclusion:

CXL as an adjunct to topical antimicrobial treatment was more effective in treating bacterial keratitis than conventional antimicrobial therapy alone, as it led to shorter recovery times due to more rapid ulcer healing, resolution of infiltration, and faster symptomatic relief in patients. Despite CXL promoted the ulcer to heal quickly, there was no significant change in V/A before and after CXL or between the CXL with antimicrobial or antimicrobial therapy alone .
Optimasi Efektivitas Gliserol Dan Kitosan Dalam Pembuatan Plastik Biodegradable Dari Pemanfaatan Biji Durian Dengan Metode Inversi Fasa
Authors:   Universitas Diponegoro, Inayah Afiyatun , Kusumayanti Heny ,   Universitas Diponegoro
Published: April 2022

Masalah lingkungan dari pembuangan limbah plastik turunan minyak bumi telah menjadi isu penting karena sifatnya yang sulit diuraikan. Oleh karena itu, upaya telah dilakukan untuk mempercepat tingkat degradasi material polimer dengan mengganti beberapa atau seluruh polimer sintetis dengan polimer alami. Pemanfaatan biji durian menjadi salah satu upaya dalam memanfaatkan zero waste product. Biji durian memiliki kandungan pati yang cukup tinggi berupa 25.9 gram amilopektin dan amilosa sebesar 20.3 gram sehingga berpotensi sebagai alternatif pengganti bahan yang memerlukan sifat-sifat pati. Pada penelitian ini pembuatan plastik biodegradable dari pemanfaatan biji durian akan dilakukan dengan metode inversi fasa menggunakan penambahan gliserol dan kitosan. Tujuan dilakukannya penelitian ini yaitu untuk mengetahui pengaruh variabel konsentrasi gliserol, kitosan dan waktu degradasi yang optimum untuk menghasilkan film plastik biodegradable dengan kualitas dan kuantitas yang baik. Sehingga dengan penelitian ini mampu memberikan analisa pengaruh penggunaan kitosan dan gliserol terhadap kualitas plastik biodegradable biji durian. Hasil penelitian uji kelarutan air bioplastik dengan nilai kadar air terbaik ditunjukkan oleh variasi gliserol 4 mL yaitu 80.25% dan yang menghasilkan nilai absorpsi terendah sebesar 76.2%. jika dibandingkan dengan persen penyerapan air plastik konvensional, nilai persen penyerapan bioplastik yang dihasilkan masih sangat tinggi.
Higher-Order Models in the Theory of Planned Behavior to Predict Whistleblowing Intention
Authors: Hamdani Ujang , Roekhudin Roekhudin , Hariadi Bambang
Published: April 2022

The low rank of Indonesia's Corruption Perception Index (CPI) 2021 indicates that government fraud is still a significant problem. One improvement in bureaucracy reform is the whistleblowing system to report wrongdoing. Although this system is applicable, the effectiveness of whistleblowing as a mechanism to detect fraud depends on the willingness of an employee to report misconduct. As a part of government management systems in local government, the internal auditor has a unique position to detect fraud as early as possible in their organization. They conduct regular monitoring of other agencies to know the fraud before. This research investigates internal auditors' intention to report fraud in the local government. By employing the theory of planned behavior, variables in this study were attitude toward whistleblowing, subjective norms, perceived whistleblowing control, and internal whistleblowing intention. This study was mixed-method research with a sequential explanatory design approach. Data were obtained from questionnaires of 201 internal auditors in local government and in-depth interviews to produce a complete study result. The researcher adopted a higher-order model in PLS-SEM to explain the relationship between components of the theoretical construct. Higher-order models facilitate a construct on a more abstract higher-level dimension and its more concrete lower-order subdimensions. The findings of this research revealed that attitude toward whistleblowing, subjective norms, and perceived whistleblowing control positively affected the intentions of the internal auditor to report wrongdoings internally. The result of this study can be implemented by the local government to effectively improve some policies related to moral education and whistleblowing systems.
Recensie van L'abbé Gantois, l'histoire / Eric Vanneufville & Nicolas Bourgeois en Frans-Vlaanderen. Confidenties in het Olmkasteel / Wido Bourel
Authors: Van Campenhout Nico
Published: April 2022

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Функция распределения электронов по энергиям в высоковольтном импульсном разряде с протяженным полым катодом
Authors: Ашурбеков Н.А. , Закарьяева М.З. , Иминов К.О. , Рабаданов К.М. , Шахсинов Г.Ш.
Published: April 2022

The dynamics of a nanosecond discharge with an extended hollow cathode in argon is studied and the electron energy distribution function (EEDF) in a plasma column is calculated. The issues of the formation of the EEDF in the discharge column and inside the cathode cavity are considered. The conditions of the validity the two-term approximation of the EEDF in the plasma column are analyzed and the appropriate evaluations are given.
6G and Artificial Intelligence Technologies for Dementia Care: Literature Review and Practical Analysis (Preprint)
Authors: Su Zhaohui , Bentley Barry L , McDonnell Dean , Ahmad Junaid , He Jiguang , Shi Feng , Takeuchi Kazuaki , Cheshmehzangi Ali , da Veiga Claudimar Pereira
Published: April 2022

BACKGROUND

The dementia epidemic is progressing fast. As the world’s older population keeps skyrocketing, the traditional incompetent, time-consuming, and laborious interventions are becoming increasingly insufficient to address dementia patients’ health care needs. This is particularly true amid COVID-19. Instead, efficient, cost-effective, and technology-based strategies, such as sixth-generation communication solutions (6G) and artificial intelligence (AI)-empowered health solutions, might be the key to successfully managing the dementia epidemic until a cure becomes available. However, while 6G and AI technologies hold great promise, no research has examined how 6G and AI applications can effectively and efficiently address dementia patients’ health care needs and improve their quality of life.

OBJECTIVE

This study aims to investigate ways in which 6G and AI technologies could elevate dementia care to address this study gap.

METHODS

A literature review was conducted in databases such as PubMed, Scopus, and PsycINFO. The search focused on three themes: dementia, 6G, and AI technologies. The initial search was conducted on April 25, 2021, complemented by relevant articles identified via a follow-up search on November 11, 2021, and Google Scholar alerts.

RESULTS

The findings of the study were analyzed in terms of the interplay between people with dementia’s unique health challenges and the promising capabilities of health technologies, with in-depth and comprehensive analyses of advanced technology-based solutions that could address key dementia care needs, ranging from impairments in memory (eg, Egocentric Live 4D Perception), speech (eg, Project Relate), motor (eg, Avatar Robot Café), cognitive (eg, Affectiva), to social interactions (eg, social robots).

CONCLUSIONS

To live is to grow old. Yet dementia is neither a proper way to live nor a natural aging process. By identifying advanced health solutions powered by 6G and AI opportunities, our study sheds light on the imperative of leveraging the potential of advanced technologies to elevate dementia patients’ will to live, enrich their daily activities, and help them engage in societies across shapes and forms.
Using a Virtual Community of Practice to Support Stroke Best Practice Implementation: Mixed Methods Evaluation (Preprint)
Authors: Linkewich Elizabeth , Quant Sylvia , Bechard Lauren , Donald Michelle
Published: April 2022

BACKGROUND

Successful best practice implementation is influenced by access to peer support and knowledge exchange. The Toronto Stroke Networks Virtual Community of Practice, a secure social media platform, is a knowledge translation tool supporting dissemination and adoption of stroke best practices for interprofessional stroke stakeholders.

OBJECTIVE

The aim of this study is to evaluate the use of a virtual community of practice (VCoP) in supporting regional stroke care best practice implementation in an urban context.

METHODS

A mixed methods approach was used. Qualitative data were collected through focus groups and interviews with stroke care provider members of the VCoP working in acute and rehabilitation settings. Thematic analysis was completed, and the Wenger Value Creation Model and developmental evaluation were used to reflect practice change. Quantitative data were collected and analyzed using website analytics on VCoP use.

RESULTS

A year after implementation, the VCoP had 379 members. Analysis of web analytics data and transcripts from focus groups and interviews conducted with 26 VCoP members indicated that the VCoP provided immediate value in supporting user networking, community activities, and interactions. Skill acquisition and changes in perspective acquired through discussion and project work on the VCoP were valued by members, with potential value for supporting practice change. Learning about new stroke best practices through the VCoP was a starting point for individuals and teams to contemplate change.

CONCLUSIONS

These findings suggest that the VCoP supports the early stages of practice change and stroke best practice implementation. Future research should examine how VCoPs can support higher levels of value creation for implementing stroke best practices.
Correlation Between Interest in COVID-19 Hair Loss and COVID-19 Surges: Analysis of Google Trends (Preprint)
Authors: Han Joseph , Kamat Samir , Agarwal Aneesh , O'Hagan Ross , Tukel Connor , Owji Shayan , Ghalili Sabrina , Luu Yen , Dautriche Svidzinski Cula , Abittan Brian J , Ungar Jonathan , Gulati Nicholas
Published: April 2022

UNSTRUCTURED

N/A
Development of Phenotype Algorithms to Identify Hidradenitis Suppurativa Using Real World Data (Preprint)
Authors: Hardin Jill , Murray Gayle , Swerdel Joel
Published: April 2022

BACKGROUND

Hidradenitis Suppurativa (HS) is a chronic, potentially debilitating, recurring inflammatory disease. Observational databases provide opportunities to study the epidemiology of HS.

OBJECTIVE

This study’s objective was to develop phenotype algorithms for HS suitable for epidemiological studies using a network of observational databases.

METHODS

A data driven approach was used to develop four HS algorithms. A literature search identified prior HS algorithms. Nine Observational Medical Outcomes Partnership (OMOP) standardized databases were used to develop two incident and two prevalent HS phenotype algorithms. Two open-source diagnostic tools, CohortDiagnostics and PheValuator, were used to evaluate and generate phenotype performance metric estimates (sensitivity, specificity, positive predictive value (PPV), and negative predictive value).

RESULTS

Two prevalent and two incident HS algorithms were developed. Validation showed PPV estimates were highest in the prevalent algorithm requiring at least two HS diagnostic codes (mean 86%). Sensitivity estimates were highest in the prevalent algorithm requiring at least one HS code (mean 58%).

CONCLUSIONS

This study illustrates the evaluation process and provides performance metrics for two incident and two prevalent HS algorithms across nine observational databases. The use of the rigorous data driven approach applied to a large number of databases provides confidence that the HS algorithms are correctly identifying HS subjects.

CLINICALTRIAL

NA
Design and Development of Surveillance Drone
Authors: Kawale Ayush , Biswas Akshay , Gajbhiye Dr. Pankaj , Dhundale Vijayanand , Meshram Ritik , Patwekar Smita , Sawargaonkar Vaishnavi , Kamdi Trishul
Published: April 2022

Abstract: In recent years, as interest in Unmanned Aerial Vehicles (UAVs) has increased, the development in the unmanned has an important technology for military and security application. Various missions can be done using this system as it will help in the surveillance in unknown areas, forestry conservation, spying enemy territory. Application which is developed in this research has a purpose to simulate condition in war zone for spying the enemy. Following current trends towards UAV innovative design a small size light UAV quad copter system was design, assembled and tested in flight. The aim is to design a low cost structure and make it comparable with other more expensive. Keywords: Unmanned Aerial Vehicles, Rescue mission, design of drone Surveillance
“Easy to join in your pyjamas”: benefits and barriers of online science engagement at Australia's 2020 National Science Week
Authors: McRae Olivia F. , Downing Ellie , Motion Alice , O'Reilly Chiara , Pullen Reyne
Published: April 2022

In 2020, National Science Week events shifted online in response to Australian COVID-19 restrictions. Our research captures this rapid pivot from in-person to online science events, exploring experiences through audience and presenter questionnaires, and follow-up interviews. We examine characteristics of audiences for online science events, benefits and barriers of these events, and opportunities for online engagement. Key benefits were ease of attendance, new experiences enabled online, and greater control and flexibility. Lack of social interaction, technology issues, and audience reliability were identified as barriers. Our research suggests online events operate in a different sphere to in-person events and informs the delivery of engaging online experiences.
Entanglement Spectroscopy and probing the Li-Haldane Conjecture in Topological Quantum Matter
Authors: Zache Torsten V. , Kokail Christian , Sundar Bhuvanesh , Zoller Peter
Published: April 2022

Topological phases are characterized by their entanglement properties, which is manifest in a direct relation between entanglement spectra and edge states discovered by Li and Haldane. We propose to leverage the power of synthetic quantum systems for measuring entanglement via the Entanglement Hamiltonian to probe this relationship experimentally. This is made possible by exploiting the quasi-local structure of Entanglement Hamiltonians. The feasibility of this proposal is illustrated for two paradigmatic examples realizable with current technology, an integer quantum Hall state of non-interacting fermions on a 2D lattice and a symmetry protected topological state of interacting fermions on a 1D chain. Our results pave the road towards an experimental identification of topological order in strongly correlated quantum many-body systems.
The influence of mounted assembly process on the stress-strain state of the lattice dome frame
Authors: Lebed Evgeny V.
Published: April 2022

The aim of the research - analysis of the stress-strain state of spherical lattice dome structure during mounted assembly process. The dome has a metal frame consisting of six repeating sectors with triangular grid cells. The mesh dome has five tiers in height. The study is devoted to establishing the dependence of the stress-strain state of the fully assembled frame of the lattice dome on the method mounted assembly. Methods. A computer model of the frame of the lattice dome made of steel I-beams in its design configuration has been developed. On its basis, assembly models of an incomplete frame for different stages of installation are created. For all models of the lattice dome frame, computer calculations were performed for the effect of the load from the own weight of its bars. As a result of calculations deformations, internal forces and stresses in the frame bars were determined at all stages of assembly, which were compared with those for the design configuration scheme. Results. Diagrams of deformations, moments and stresses in the bars of the dome frame at all stages of mounted installation are obtained. Comparative diagrams of installation and design stresses in the bars of the lattice dome are presented. The assessment of the installation stress state of the frame is given, and their inevitability and influence on the initial stress state of the lattice dome are noted.
Case study on structural health assessment for existing reinforced concrete building
Authors: Adhikari Kushum Prasad , Lamichhane Govind Prasad , Lamichhane Kshiteez , Ghimire Krishna
Published: April 2022

Retrofitting is a method of renovating/repairing and strengthening the weak structure that was affected due to the excessive load on structure during any uncertainty load like earthquake or due to end of service life of the infrastructure. The objectives of this paper are to design reinforced concrete and fiberreinforced polymer jacketing of failed columns of an existing building, after addition of two more storey in previous design and to compare suitability of before mentioned methods of retrofitting. The presented work also describes design procedure of reinforced concrete, carbon fiber reinforced polymer jacketing for strengthening existing columns. This study is fruitful to gauge suitability of the two retrofitting methods for weakened structural members. The existing buildings in Nepal designed as using Mandatory Rules of Thumb are most vulnerable types of building; to mitigate further crack in structural members with appropriate type of retrofit will be considered with proper management of construction related to post-earthquake activity. After analysis and design of existing building its extremely necessary to plan construction management for economic and safety concern. Most cases of such projects will lead improper work without proper construction management leading uneconomic and prolonging of completion of project.
Influence of constructive solutions on the stiffness characteristics of the rammed monolithic reinforced concrete cone-shaped piles with side and bottom forms from crushed stones
Authors: Kuzhakhmetova Elvira R.
Published: April 2022

Relevance. The article discusses the design solutions of a new pile structure, which is a monolithic reinforced concrete cone-shaped pile, enclosed in a crushed stone shell and resting on a spherical crushed stone broadening. In the course of a numerical study, carried out using the finite element method, the influence of the geometric parameters of the crushed stone formations of the pile foundation, such as the wall thickness of the crushed stone shell and the radius of the crushed stone broadening, on its bearing capacity was revealed. The aim of the study is to perform a comparative numerical analysis of the stressstrain state of a pile structure with different design solutions, operating as part of a soil massif. Materials and methods. Numerical static analysis of the structure of a monolithic reinforced concrete pile foundation operating in a soil massif was carried out using a spatial finite element model in the CAE-class software package. The article presents the results of a numerical analysis of the stress-strain state of a rammed monolithic reinforced concrete cone-shaped pile with different wall thicknesses of the crushed stone shell and different diameters of the lower spherical crushed stone broadening. The analysis showed that changes in the specified geometric parameters of the pile foundation have a significant impact on its bearing capacity under external forces. The rational choice of these parameters allows you to economically use the concrete mixture and reinforcing rods intended for the manufacture of monolithic reinforced concrete rammed piles, which, in turn, leads to a decrease in financial costs for the manufacture of the pile foundation and the entire building as a whole. The next research is supposed to carry out a comparative analysis of the numerical results with experimental data obtained in laboratory and field conditions.
Thermal processing of fresh concrete with infrared radiation
Authors: Svintsov Alexander P. , Cisse Alimu
Published: April 2022

Currently, the construction of buildings made of monolithic concrete and reinforced concrete is becoming increasingly relevant. The use of innovative technologies, minimum construction time, durability, reliability, the ability to perform work in various climatic conditions, architectural individuality contribute to the development of monolithic construction. Concrete and reinforced concrete are the main materials of modern construction. The quality of structures depends not only on the composition of concrete, the amount of portland cement, the chemical additives used, the water-cement ratio, the quality of fillers, etc., but also significantly on the heat and humidity regime of concrete holding. To ensure the necessary temperature conditions for hardening and strength gain of concrete, various methods of heating structures are used. One of the methods of concrete care is thermal processing during the hardening period and the acquisition of critical or design strength. The aim of the study is to improve the technology of erection of monolithic concrete and reinforced concrete structures using thermal processing of concrete by means of infrared radiation. The technology of thermal processing of the laid and compacted concrete mixture using infrared heating and a two-chamber transparent shelter for infrared rays has been developed. The obtained results permit us to provide conditions for the normal course of the chemical reaction of hydration, hardening and strength gain. This allows successfully solve the problems of concreting in the erection of buildings and structures made of monolithic concrete and reinforced concrete.
LEGAL REGULATION OF VOLUNTEER ACTIVITIES WITHIN THE SOCIOCULTURAL SPACE OF THE YOUNGER GENERATION
Authors:   Сочинский государственный университет, Сочи, Россия, Вита Александровна Фоменко , Михаил Максимович Никитин ,   Сочинский государственный университет, Сочи, Россия
Published: April 2022

The article examines the features of a number of branches of legal regulation of volunteer (volunteer) activities. The constitutional, civil, international, organizational components of the volunteers' activities are characterized; conclusion of a civil law contract with volunteers. The influence of economic, legal and social events on the development of the potential of volunteering. The sociocultural attitudes and values that begin to emerge in connection with the participation of volunteers in event activities are studied. The legal regulation of volunteering is considered on the basis of the following sources – codes, federal laws, social programs, standards, regulations. The study and analysis of the legal regulation of volunteer activities is carried out within the framework of the socio-cultural space of youth, where complex processes of globalization and regionalization, universalization of modern society and the diversity of its local manifestations are intertwined.
HOW DOES A CRIMINAL RECORD “WORK”?
Authors:   Южный федеральный университет, Ростов-на-Дону, Россия, Наталья Викторовна Артеменко , Нина Георгиевна Шимбарева ,   Южный федеральный университет, Ростов-на-Дону, Россия
Published: April 2022

A criminal record as a consequence of convicting a person for committing a crime with imposition of punishment results in criminal legal and a significant number of general legal consequences. Furthermore, if the mechanism of criminal legal consequences is developed adequately, the application of general legal consequences of a criminal record triggers many questions. The latter are set forth by a large number of federal laws of a different non-criminal legal profile and are valid even when the criminal record is cancelled or released and the criminal legal relations are terminated accordingly. The authors consider the disorganized, numerous and fundamentally life-long restrictions (specifically on the human right to dispose of the abilities for work freely) do not correspond to the fundamental principles of the legal status of an individual in a democratic society, and they do contradict the very concept of a criminal record as a temporary legal status of a convicted body, and they do violate the principle of justice.
KEANEKARAGAMAN AMFIBI (ORDO ANURA) DI HUTAN LINDUNG GAMBUT LONDERANG TANJUNG JABUNG TIMUR
Authors: Azhari Asri , Sukmono Tedjo , Prima Nugraha Anggit , Ihsan Mahya , Suprayogi Dawam
Published: April 2022

Hutan gambut merupakan hutan tropis dan menjadi sumber daya alam yang unik yang dapat mendukung keanekaragaman flora dan fauna termasuk amfibi. Hutan gambut sering mengalami kebakaran pada saat musim kemarau. Kebakaran dapat mengancam kelangsungan hidup sejumlah flora dan fauna tak terkecuali amfibi. Penelitian ini bertujuan untuk mengetahui jenis dan komposisi amfibi serta untuk mengetahui indeks keanekaragaman dan kemerataan amfibi di Hutan Lindung Gambut (HLG) Tanjung Jabung Timur. Penelitian ini menggunakan metode Visual Encounter Survey (VES) yang dikombinasikan dengan transek. Transek merupakan transek akuatik yang dibuat sepanjang 500m. Data yang telah diperoleh dianalisis dengan menggunakan Indeks Shannon Wiener dan dengan menghitung kemerataan jenis. Hasil penelitian yaitu jenis amfibi yang didapat ada 4 jenis (Fejervarya limnocharis, Fejervarya cancrivora, Hylarana erythraea dan Pulchrana baramica). Nilai keanekaragaman tergolong sedang dengan nilai H’= 1, 03. Hal ini menunjukkan secara ekologis kondisi habitat di HLG Londerang mampu untuk mendukung keberadaan jenis amfibi. Nilai kemerataan jenis amfibi menunjukkan nilai E= 0,74 yang berarti pensebaran amfibi tergolong cukup merata.
EFEK RESIDU BIOCHAR SEKAM PADI DAN PUPUK KANDANG AYAM TERHADAP PERTUMBUHAN DAN HASIL TANAMAN JAGUNG (Zea mays L.)
Authors: Mapegau Mapegau , Setyaji Hajar , Hayati Islah , Putri Ayuningtiyas Septiani
Published: April 2022

Penelitian ini dilakukan untuk mengetahui efek residu biochar sekam padi dengan pupuk kandang ayam terhadap pertumbuhan dan hasil tanaman jagung.Penelitian dilaksanakan di Teaching and Research Farm Fakultas Pertanian Universitas Jambi dari bulan April sampai dengan Agustus 2019, satu tahun setelah penelitian biochar pada tanaman jagung dilaksanakan pada lokasi yang sama. Sebagai rancangan lingkungan digunakan rancangan acakkelompok (RAK) 3 ulangan sesuai dengan rancangan penelitian awal. Dosis residu biochar sebagai perlakuan 2,5 ton/ha, 5,0 ton/ha, dan 7,5 ton/ha. Pupuk kandang ayam 2,5 ton/ha, 5,0 ton/ha, dan 7,5 ton/ha. .Hasil penelitian menunjukkan bahwa residu biochar sekam padi masih berpengaruh terhadap pertumbuhan dan hasil tanaman jagung, sedang pupuk kandang ayam tidak mempengaruhi pertumbuhan tinggi, diameter batang,  dan hasil biji kering tanaman jagung. Residu biochar sekam padi dengan dosis5,0 dan 7,5 ton.ha-1 memberikan pertumbuhan dan hasil terbaik pada tanaman jagung.Tidak ada perbedaan pertumbuhan dan hasil yang diperoleh pada penelitian awal dengan yang diperoleh pada penelitian residu.
PERILAKU POLITIK GENERASI MILENIAL: SEBUAH STUDI PERILAKU MEMILIH (VOTING BEHAVIOR)
Authors: Alfaruqy Muhammad Zulfa
Published: April 2022

Introduction The millennial generation had been using their suffrage during the president and vice president election. But, it is still leaving a big question about how is the voting behavior of the millennial generation. It will be important to be understood as the right strategy to obtain their vote in the next election at various competition level. This study aims to explore the factors which influence the voting behavior and categorize the type of voter from the millennial generation.Method This qualitative study using focus group discussion and questionnaire which contains open-ended questions to collect the data. It involves 38 college students of Diponegoro University which enroll the political psychology class/subject.Result The result of this study shows that voting behavior of millennial generation depends on the candidate personality, the enticement, and the voter perception, also the social environment of a candidate and the social environment of the voter. They tend to be categorized as the psychological and rational voter.Conclusion And Recommendation This study has a theoretical implication that the personality of the candidate is quite important toward the voting behavior of the millennial generation. So to get their acceptance, the candidate and victory board have to show the positivity of the candidate in addition to offer the attractive vision, mission, and future program.
Keyword: millennial, rational, voting behavior.
ABSTRAK
Pendahuluan Generasi milenial telah menggunakan hak pilih dalam kontestasi pemilu presiden dan wakil presiden. Meskipun demikian, ada pertanyaan besar perihal bagaimana sesungguhnya perilaku memilih (voting behavior) generasi milenial guna memahami strategi yang tepat dalam memperoleh dukungan suara pada pemilu-pemilu selanjutnya, di berbagai level kompetisi. Oleh karena itu, tujuan penelitian adalah untuk mengeksplorasi faktor-faktor yang mempengaruhi perilaku memilih dan kategorisasi tipe pemilih generasi milenial.
Metode Penelitian kualitatif ini menggunakan penggalian data dengan kuesioner yang berisi pertanyaan terbuka. Penelitian melibatkan 38 mahasiswa Universitas Diponegoro yang mengambil mata kuliah Psikologi Politik sebagai subjek.
Hasil penelitian menunjukkan bahwa perilaku memilih dipengaruhi oleh personal kandidat, tawaran kandidat, persepsi pemilih, lingkungan sosial pemilih, dan lingkungan sosial kandidat. Mereka cenderung terkategorisasi sebagai pemilih psikologis dan rasional.
Kesimpulan dan Saran Penelitian memiliki implikasi teoretis yang mendukung personal kandidat sebagai faktor yang berpengaruh dominan terhadap perilaku memilih generasi milenial. Jika ingin mendapatkan suara generasi milenial, maka kandidat dan tim sukses perlu mengedepankan figur positif kandidat, di samping mengemas tawaran visi-misi dan program kerja dalam kampanye yang menarik.
Kata kunci: milenial, rasional, perilaku memilih
PREPARATION OF YB-DOPED SRCEO3 SPUTTER TARGETS FOR PROTONIC SOLID OXIDE FUEL CELLS
Authors: PİŞKİN Fatih
Published: April 2022

A comprehensive study was carried out starting from powder synthesis to sintering procedure in order to produce a phase-pure SrCe0.95Yb0.05O3-δ sputter target. In the powder synthesis, the effect of chelating and polymerization agents on the formation of single-phase SrCe0.95Yb0.05O3-δ was investigated in detail. In this regard, citric acid, EDTA, and their combinations in different ratios were evaluated as chelating agents. The calcination temperature, ranging from 1000 °C to 1300 °C, was also investigated to reveal its effect on the formation of possible secondary phases. Following the powder synthesis, SrCe0.95Yb0.05O3-δ sputter target with dimensions of ~50 mm diameter and ~3 mm thickness was produced by powder pressing with deformable compaction die and the subsequent sintering at 1300 °C for 10 hours. A relative density of 0.95 was achieved in SrCe0.95Yb0.05O3-δ targets as a result of the procedure in question without the use of a sintering aid.
Green-up and brown-down: Modelling grassland foliage phenology responses to soil moisture availability
Authors: Yang Jinyan , Medlyn Belinda , Barton Craig , Churchill Amber , Kauwe Martin De , Jiang Mingkai , Krishnananthaselvan Arjunan , Tissue David , Pendall Elise , Power Sally
Published: April 2022

Grassland responses to drought are strongly mediated by leaf phenology,
with greening and browning being highly sensitive to soil moisture.
However, this process is represented overly simplistically in most
vegetation models, limiting their capacity to predict grassland
responses to global change factors. We derive functions representing
grassland phenological responses to soil water content (SWC), by fitting
an empirical model to greenness data. Data were obtained from fixed
cameras (phenocams) monitoring phenology at several grassland
experiments in Sydney, Australia. The data-model synthesis showed that
the sensitivity of growth to SWC exhibited a concave-down response in
most species. For senescence, we found a strong nonlinear increase in
senescence rate with declining SWC. Both findings contradict common
assumptions in vegetation models. Incorporating nonlinear responses in
the empirical model reduced the error in cover predictions by 12%.
Model evaluation against data from drought treatments indicated that
differential sensitivity of phenology to SWC helps explain differences
among species’ responses to variable rainfall. Our work provides a new
methodology, and new evidence, to support the development of improved
representations of grassland phenology for vegetation models.
Sexual perception does not modulate male short-term fitness components in Drosophila melanogaster.
Authors: Corbel Quentin , Londoño-Nieto Claudia , Carazo Pau
Published: April 2022

Phenotypic plasticity in reproductive behaviour can be a strong driver
of individual fitness. For example, in species with high intra-sexual
competition, changes in socio-sexual context can trigger quick adaptive
plastic responses in males. In particular, a recent study in the vinegar
fly (Drosophila melanogaster) shows that males respond adaptively
to perception of female cues in a way that increases their reproductive
success, but we ignore the underlying mechanisms of this phenomenon.
Here, we aimed to fill this gap by investigating the short-term effects
of female perception on male pre- and post-copulatory components of
reproductive success: a) mating success, b) mating latency and duration,
c) sperm competitiveness, and d) ejaculate effects on female receptivity
and oviposition rate. We found that brief sexual perception increased
mating duration, but had no effect on the main pre- or post-copulatory
fitness proxies. These results tie up with previous findings to suggest
that male adaptive responses to sexual perception are not due to a
short-term advantage, but rather to fitness benefits that play out
across the entire male lifespan.