bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlating the morphology of Anacardium occidentale L. fruits from 30 orchards with their physicochemical and nutritional properties
Authors: Dakuyo Roger , Konaté Kiessoun , Bazié David , Sanou Abdoudramane , Kaboré Kabakdé , Sama Hemayoro , Santara Balmoussa , Konkobo Frédéric Anderson , Dicko Mamoudou Hama
Published: December 2022

Cashew (Anacardium occidentale L.) is a cross-pollinating plant whose fruit consists of two parts, the nut, and the apple. This study aimed to carry out agro-morphological characteristics of cashew fruits to establish relationships with their physicochemical and nutritional properties. Thirty (30) cashew accessions fruits were sampled in different regions of Burkina Faso. The length, width, thickness, weight, yield, kernel output ratio (KOR), proximate composition, specific minerals, phenolic compounds, and anti-nutritional factors were assessed. Evaluations were made using standard methods. The results showed significant variations in agro-morphological, physicochemical and nutritional traits depending on the accessions and the organ. Also, the ratio of apple mass versus nut one was about 12.24 ± 1.24. Kernels are an important source of proteins, fat, total phenolic compounds, and flavonoids, with average contents of 22.84 ± 1.25 g/100 g, 51.65 ± 2.54 g/100 g, 9.78 ± 2.15 mg GAE/g, and 6.24 ± 12.15 mg QE/g, respectively. As for the apples, they contained substantial quantities of Potassium, Phosphorus, Chlorine, and Magnesium with contents of 611.24 ± 14.5 mg/100 g, 418.24 ± 16.47 mg/100 g, 332.24 ± 10.54 mg/100 g, and 224.95 ± 13.15 mg/100 g, respectively. Statistical analyses showed that mineral and phytate contents were positively correlated to cashew apples while phenolic compounds and tannins were strongly correlated with walnuts. Principal component analyses showed three groups of accessions based on apples and kernels characteristics. These data showed a direct relationship between cashew physicochemical, nutritional potentials, kernels, and apples’ agro-morphological characteristics. These data constitute an important basis for the identification of cashew accessions with high nutritional and economic potential.
The red/blue light ratios from light-emitting diodes affect growth and flower quality of Hippeastrum hybridum ‘Red Lion’
Authors: Wang Shunli , Liu Xiaoting , Liu Xiaoning , Xue Jingqi , Ren Xiuxia , Zhai Yanning , Zhang Xiuxin
Published: December 2022

Light quality strongly impacts the growth and flower quality of ornamental plants. The optimum light quality for the growth and flowering of Hippeastrum remains to be validated. In the present study, we investigated the effect of the red/blue light ratio of LEDs on the growth and flowering quality of H. hybrid ‘Red Lion’. Two LEDs with red/blue light ratio of 1:9 (R10B90) and 9:1 (R90B10) were designed. LEDs of white light were the control. In the earlier vegetative and reproductive growth phase, R90B10 increased the biomass of the bulbs, leaves, and flowers. Compared with the control and R10B90 group, R90B10 LEDs delayed flowering by 2.30 d and 3.26 d, respectively. Based on chlorophyll contents, photosynthetic capacity, chlorophyll fluorescence parameters, and carbohydrate contents, the photosynthesis rate was higher in the R10B90 group. Optimal red and blue light intensity promoted the accumulation of carbohydrates and early flowering and prolonged the flowering period of H. hybrid. Microscopic analysis showed that stomatal density was high, and the number of chloroplasts was large in the R10B90 treatment group, which enhanced photosynthesis. Particularly, R10B90 promoted the expression of seven key genes related to chlorophyll synthesis. R10B90 also promoted early overexpression of the HpCOL gene that promotes early flowering. Thus, higher blue light and 10% red light intensities promote early and extended flowering, while higher red light and 10% blue light promote vegetative plant growth but delay flowering.
Pollen viability-based heat susceptibility index (HSIpv): A useful selection criterion for heat-tolerant genotypes in wheat
Authors: Khan Irum , Wu Jiajie , Sajjad Muhammad
Published: December 2022

Terminal heat stress during reproductive stage in wheat (Triticum aestivum L.) causes pollen grain sterility and has a drastic impact on wheat crop production. Finding genotypes with high pollen viability under heat stress is crucial to cope with the impact of climate change through developing heat-tolerant cultivars. To assess the effect of terminal heat stress on pollen viability in a panel of spring wheat genotypes (N = 200), RCBD (randomized complete block design) field trials were conducted under normal and heat stress conditions for two consecutive years (2020–2021 and 2021–2022). Analysis of variance showed significant variation in genotypes, treatments, and genotype × treatment interaction. Fifty and 46 genotypes were categorized as heat tolerant (HSIpv < 0.5) in the first and second year, respectively. Twelve genotypes, namely, Chenab-70, Pari-73, Pak-81, MH-21, Punjab-76, NIFA-Aman, NUWYT-63, Swabi-1, Nisnan-21, Frontana, Amin-2000, and Pirsabak-2004, were found to be heat tolerant across the years. The violin plot displayed a trend of improvement in heat tolerance (HSIpv < 0.5) over the period of time in many modern wheat varieties. However, some modern wheat varieties released after 2001 such as Janbaz-09 (57%), Ghazi-2019 (57%), and Sindhu-16 (43%) had very low pollen viability under heat stress conditions. The results of phenotypic coefficient of variance (PCV%), genotypic coefficient of variance (GCV%), broad sense heritability (h2bs), and genetic advance (GA) suggested the major contribution of genetic factors in controlling pollen viability trait. Higher values of h2bs and GA under heat stress conditions suggested pollen viability as a heat tolerance trait controlled by additive genetic effects. Taken together, these results suggested pollen viability as a useful trait for selection in early generations under elevated temperatures. The genotypes identified as heat tolerant in both years can be used as genetic resources for breeding cultivars with higher pollen viability under elevated temperature conditions.
Whole-transcriptome analyses of Sorghum leaves identify key mRNAs and ncRNAs associated with GA3-mediated alleviation of salt stress
Authors: Wu Yanqing , Liu Jiao , Zhou Guisheng
Published: December 2022

Sorghum has recently attracted much attention for its tolerance in high salt environment. However, the effect and regulatory mechanism of the gibberellic acid (GA3)-mediated alleviation of salt stress in sorghum remains unclear. Herein, we reported that a GA3 concentration of 50 mg/L is optimal for sorghum (“Jitian 3”) development under salt stress. We conducted a whole-transcriptome analysis between GA3-treated and control sorghum leaves under salt stress, and we identified 1002 differentially expressed (DE)-messenger RNAs (mRNAs), 81 DE-long non-coding RNAs (lncRNAs), 7 DE-circular RNAs (circRNAs), and 26 DE-microRNA (miRNAs) in sorghum following GA3 treatment. We also identified a majority of DE-mRNAs and non-coding RNAs (ncRNAs) targets that serve essential roles in phenylpropanoid biosynthesis and plant hormone networks. In addition, we generated a competitive endogenous RNA (ceRNA)-miRNA-target gene network, and 3 circRNAs (circRNA_2746, circRNA_6515, circRNA_5622), 4 lncRNAs (XR_002450182.1, XR_002452422.1, XR_002448510.1, XR_002448296.1) and 4 genes (LOC8056546, LOC8062245, LOC8061469, LOC8071960) probably act as valuable candidates for the regulation of the GA3-mediated alleviation of salt stress in sorghum. Our findings uncovered potential mRNA and non-coding RNAs that contribute to GA3 regulation, thus offering a basis for the future investigation of underlying mechanisms of salt stress in sorghum.
Safety evaluation of FAD2 RNAi transgenic Brassica napus L. based on microbial diversity and metabonomic analysis
Authors: Qi Yanting , Wang Qiming , Xie Qingxuan , Wu Chuan , Xu Minhui , Han Shaofan , Zhou Ting , Li Juan , Xia Libing , Li Wai chin , Pan Weisong
Published: December 2022

Oleic acid desaturase (FAD2) is the key enzyme that produces polyunsaturated fatty acids in rapeseed (Brassica napus L), which is one of the main oil crops. RNA interference (RNAi) is an emerging technique that provides new opportunities for the generation of new traits in plants. To increase oleic acid content and reduce linoleic and linolenic acid content in rapeseed, we constructed an ihpRNA plant expression vector of the FAD2 gene and obtained transgenic plants for multiple generations by stable inheritance. In this study, third-generation transgenic plants (T3), seventh-generation transgenic plants (T7), and wild-type plants (WT) were used. The differences in microbial community diversity between transgenic plants and wild-type plants and the up- and downregulation of rhizosphere metabolite contents were investigated. In conclusion, the results showed that the soil microbial community structure was stable, the general microbial community structure was not changed by the transgenic rhizosphere exudates, and no significant harmful root exudate of transgenic rapeseed on the environment was found through the microbial community and metabolomics analysis. This work may provide an understanding of the impact of RNAi on plant metabolites and a safety evaluation method for transgenic plants and a reference for rapeseed breeding.
Well under control: Control demand changes are sufficient for metacontrol
Authors: Kang Moon Sun , Yu-Chin Chiu
Published: December 2022

Metacontrol arises from the efficient retrieval of cognitive control by environmental cues that are predictive of the upcoming control demands. Previous studies have demonstrated that proactive and reactive metacontrol can be indexed by a list-wide switch probability (LWSP) and an item-specific switch probability (ISSP) effect, respectively. However, what triggers metacontrol in the first place has not been clearly articulated. While a “mere-experience” hypothesis attributes metacontrol to changes in control demands, an “affective-signaling” hypothesis suggests that high control demands are aversive and aversiveness drives metacontrol. In two experiments, we adjudicated between these hypotheses by considering the modes of metacontrol (proactive vs. reactive) and temporal dynamics of background valence (sustained vs. transient and positive vs. negative). We induced metacontrol (proactive or reactive) in a task-switching paradigm and created background valence by using positive and negative images as stimuli. With valence being an irrelevant aspect of the task, the design allows us to test whether (task-irrelevant) background valence would modulate metacontrol. While we were able to replicate the LWSP effect in Experiment 1 and the ISSP effect in Experiment 2, we did not find valence modulating either effect, regardless of the background valence being a sustained (Experiment 1) or a transient one (Experiment 2). These findings together suggest that negative valence (i.e., aversiveness) does not necessarily benefit metacontrol, and control demand variations are sufficient to induce metacontrol.
Parental burnout and resilience intervention among Chinese parents during the COVID-19 pandemic
Authors: Liu Yixiao , Chee Jing Han , Wang Ying
Published: December 2022

Introduction

Parental burnout is a mental state that combines long-term stress and depression with an overwhelming feeling of parental pressure.

Methods

In Study 1, we conducted a web-based survey of 390 Chinese parents (75.1% mothers) with children aged 1–18 years old (Mean age = 9.05 years, SD = 5.098) to examine the parental burnout during the COVID-19 global pandemic and to identify associated factors during the national lockdown. In Study 2, eight weeks of resilience intervention was administered to 20 parents to compare parental resilience and parental burnout before and after the intervention.

Results

The correlational study showed that greater parental burnout occurred in parents with the lower educational levels and in parents of school-age children. The risk factors of parental burnout included household burden and children’s interference with work; while protective factors included living materials, family atmosphere, and parent–child meeting frequency. The intervention study showed the effectiveness of meditation intervention in resilience and parental burnout, suggesting that meditation training can effectively increase parental resilience and reduce parental burnout.

Discussion

These findings demonstrate the risk and protective factors associated with parental burnout during the COVID-19 lockdown and highlight the positive role of meditation in mitigating parental burnout.
Does media sentiment affect stock prices? Evidence from China’s STAR market
Authors: Dong Xiuliang , Xu Shiying , Liu Jianing , Tsai Fu-Sheng
Published: December 2022

Objective

This paper explores the impact of media sentiment on stock prices on the Shanghai Stock Exchange Science and Technology Innovation Board (hereinafter the STAR market) from a behavioral finance perspective.

Methods

We collect Baidu News coverage of STAR-listed firms as the text, and measure text sentiment using a machine learning-based text analysis technique. We then empirically examine the impact of media sentiment on STAR market stock prices from two aspects: IPO pricing efficiency and IPO first-day stock performance.

Results

(1) Media sentiment has no significant impact on IPO pricing efficiency, thus suggesting that institutional investors participating in such offerings are generally not affected by media sentiment. (2) Optimistic media sentiment has a positive impact on IPO first-day returns, which indicates that individual investors are more easily influenced by media sentiment and therefore likely to abandon their rational judgment. (3) Media sentiment had a greater impact on IPO first-day returns during the COVID-19 pandemic than those before it, which suggests that individual investors are more influenced by media sentiment during pandemics.

Discussion

Our findings deepen the understanding of stock price formation on the STAR market, which provide a statistical basis for formulating policy directions and investment strategies.
Flattening the COVID-19 curve: Emotions mediate the effects of a persuasive message on preventive action
Authors: Muis Krista Renee , Sinatra Gale M. , Pekrun Reinhard , Kendeou Panayiota , Mason Lucia , Jacobson Neil G. , Van Tilburg Wijnand Adriaan Pieter , Orcutt Ellen , Zaccoletti Sonia , Losenno Kelsey M.
Published: December 2022

Introduction

Across four countries (Canada, USA, UK, and Italy), we explored the effects of persuasive messages on intended and actual preventive actions related to COVID-19, and the role of emotions as a potential mechanism for explaining these effects.

Methods

One thousand seventy-eight participants first reported their level of concern and emotions about COVID-19 and then received a positive persuasive text, negative persuasive text, or no text. After reading, participants reported their emotions about the pandemic and their willingness to take preventive action. One week following, the same participants reported the frequency with which they engaged in preventive action and behaviors that increased the risk of contracting COVID-19.

Results

Results revealed that the positive persuasive text significantly increased individuals’ willingness to and actual engagement in preventive action and reduced risky behaviors 1 week following the intervention compared to the control condition. Moreover, significant differences were found between the positive persuasive text condition and negative persuasive text condition whereby individuals who read the positive text were more willing and actually engaged in more preventive action compared to those who read the negative text. No differences were found, however, at the 1-week follow-up for social distancing and isolation behaviors. Results also revealed that specific discrete emotions mediated relations between the effects of the texts and preventive action (both willing and actual).

Discussion

This research highlights the power of educational interventions to prompt behavioral change and has implications for pandemic-related interventions, government policy on health promotion messages, and future research.
Differences in the moderating role of supervisors’ and subordinates’ cognition on distributive justice in the relationship between psychological contract and organizational identification
Authors: Shen Yan
Published: December 2022

Introduction

In the process of social exchange between employees and organizations, psychological contract, organizational identification, and cognition on distributive justice are closely related and have a common psychological basis, that is, the reciprocity of exchange. The question of how a sense of fairness can affect employees’ psychology and behavior has attracted the attention of scholars and managers.

Methods

The predictive role of psychological contract on organizational identification and the moderating role of supervisors’ and subordinates’ cognition on distributive justice in it were investigated. A paired sample of 133 supervisors and 437 direct reports collected from private service-based SMEs was analyzed through structural equation modeling.

Results

(1) relational psychological contract had a positive predictive effect on organizational identification and transactional psychological contract had a negative predictive effect on organizational identification; (2) subordinates’ cognition on distributive justice played a moderating role in the prediction of psychological contract to organizational identification, and supervisor’s cognition on distributive justice on subordinate’s psychological contract and organizational identification did not reach a significant level.

Discussion

This indicates that there was a significant difference between supervisors’ and subordinates’ cognition on distributive justice.
The effects of providing peer feedback on learners’ genre awareness in English as a foreign language business letter writing
Authors: Wu Huizhen , Zhu Huimin , Yang Xiaohu
Published: December 2022

Despite the important role of the genre awareness in facilitating the effective communication in the global business context and the need to teach and practice writing for various social purposes, there was scant classroom-based research on effects of providing peer feedback on EFL learners’ genre awareness in business writing for fulfilling the particular communicative purpose. This study examined whether student reviewers could improve their genre awareness in business letter writing by providing peer feedback to other students’ writings at varying levels. Sixty business English majors, taking the business writing course for 1 year under the tutelage of the same instructor, participated in the current study. They were randomly assigned to the experimental group who reviewed the students’ drafts at different levels (high, medium and low) and gave written comments and the control group who received no treatment but did self-revision. Both groups followed the genre-specific evaluation criteria during peer feedback and self-revision. Repeated-measures ANOVA on the two groups’ writing performances at different timepoints (pretest, immediate posttest, transfer posttest and delayed transfer posttest) demonstrated that the participants in the experimental group had better performance than those in the control group at the transfer posttest as well as the delayed transfer posttest. Moreover, providing weakness comments on both the low-quality and the medium-quality drafts had significant effects on their own writing quality at the subsequent tests, whereas providing strength feedback on the high-quality drafts had statistically significant impacts on their own writing quality at the immediate posttest and the delayed transfer posttest. However, multiple linear regression analyses demonstrated that only offering weakness comments to the medium-quality drafts could effectively predict the reviewers’ overall writing quality in the immediate posttest, the transfer posttest, and the delayed transfer posttest. Tentative research and pedagogical implications of the findings were discussed.
Impact of technological innovation on corporate leverage in China: The moderating role of policy incentives and market competition
Authors: Ren Lin , Liu Dan , Xiong Deping
Published: December 2022

Due to its capital-related nature, corporate leverage is highly exposed to financial risk, and optimizing corporate leverage is an effective method of mitigating financial risk to maximize corporate value. We use a two-way fixed effects model to examine the impact of technological innovation on corporate leverage using panel data of A-share listed companies in the Chinese manufacturing sector from 2012 to 2020. The results show that technological innovation and corporate leverage exhibit significant heterogeneity in cross-sectional, spatial and temporal dimensions. By further distinguishing between the effects of policy incentives and market competition, we find that the former exerts an “investment crowding out” effect and the latter an “innovation spillover” effect. These factors mitigate the negative relationship between technological innovation and corporate leverage. In general, this study provides empirical evidence for the rational allocation of resources by the Chinese government, the development of innovation capabilities, and the adjustment of leverage by firms from various regions.
Layered habitats: An evolutionary model for present-day recreational needs
Authors: Stoltz Jonathan
Published: December 2022

Urbanisation and lifestyle-related illnesses increase globally. This highlights the need to shape modern human habitats to support basic recreational needs, promoting such things as physical activity and restoration of high stress levels and cognitive fatigue. Previous research suggests eight perceived qualities in the outdoor environment, described as eight perceived sensory dimensions, as universally meaningful to people in this regard. However quite extensively studied in relation to various health and wellbeing outcomes, human sensitivity and appreciation for these qualities has not yet been explicitly analysed from an evolutionary perspective. This paper investigates their possible evolutionary roots and suggests an order for their development. This is linked with empirical findings on their relative capacity to support restoration of stress and cognitive fatigue. Qualities of earlier origin are suggested to correspond to older, more fundamental adaptations. Each subsequently developed quality implies an increased complexity of our environmental relations, associated with higher demands on more recently developed capacities. The proposed model thus links the more restorative Serene, Sheltered, Natural, and Cohesive perceived sensory dimensions with earlier stages of our development while the more demanding Diverse, Open, Cultural, and Social qualities are associated with more recent transitions. It might be of relevance when shaping modern human habitats from a health-promoting perspective, and have applications in the planning and design of, e.g., health care settings, rehabilitation gardens, urban green areas, recreational forests or other similar outdoor environments.
A theoretical review on the role of positive emotional classroom rapport in preventing EFL students’ shame: A control-value theory perspective
Authors: Kang Chunxiao , Wu Jianxiao
Published: December 2022

Background

Second/foreign language teaching has been considered as a dialogic and interactive job in which teachers’ and students’ emotions and behaviors are closely connected to each other. When there is a harmonious and positive relationship between the teacher and students in the classroom, many favorable academic outcomes may emerge. A bulk of research has endorsed the power of positive emotional classroom rapport in EFL contexts. However, its role in preventing negative students’ emotions like shame, as an achievement emotion, in terms of perceived control and value tasks has rarely (if any) caught scholarly attention.

Objective

This study aimed to provide insights into the role of emotions in L2 education and the way students’ shame can be prevented or curbed in light of a positive emotional classroom rapport.

Method/Design

This article systematically reviewed the theoretical and empirical underpinnings of EFL teachers’ positive emotional classroom rapport and students’ shame in light of the control-value theory.

Results

In this research, it was asserted that by building a positive emotional classroom rapport EFL teachers can block and even eliminate students’ shame.

Implications

The study offers practical implications to EFL teachers, trainers, principals, and researchers by increasing their knowledge and abilities in managing psycho-emotional mechanisms and factors and enriching interpersonal aspects of EFL education.
Predicted as observed? How to identify empirically adequate theoretical constructs
Authors: Witte Erich H. , Stanciu Adrian , Zenker Frank
Published: December 2022

The identification of an empirically adequate theoretical construct requires determining whether a theoretically predicted effect is sufficiently similar to an observed effect. To this end, we propose a simple similarity measure, describe its application in different research designs, and use computer simulations to estimate the necessary sample size for a given observed effect. As our main example, we apply this measure to recent meta-analytical research on precognition. Results suggest that the evidential basis is too weak for a predicted precognition effect of d = 0.20 to be considered empirically adequate. As additional examples, we apply this measure to object-level experimental data from dissonance theory and a recent crowdsourcing hypothesis test, as well as to meta-analytical data on the correlation of personality traits and life outcomes.
The impact of machine learning in predicting risk of violence: A systematic review
Authors: Parmigiani Giovanna , Barchielli Benedetta , Casale Simona , Mancini Toni , Ferracuti Stefano
Published: December 2022

Background

Inpatient violence in clinical and forensic settings is still an ongoing challenge to organizations and practitioners. Existing risk assessment instruments show only moderate benefits in clinical practice, are time consuming, and seem to scarcely generalize across different populations. In the last years, machine learning (ML) models have been applied in the study of risk factors for aggressive episodes. The objective of this systematic review is to investigate the potential of ML for identifying risk of violence in clinical and forensic populations.

Methods

Following Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines, a systematic review on the use of ML techniques in predicting risk of violence of psychiatric patients in clinical and forensic settings was performed. A systematic search was conducted on Medline/Pubmed, CINAHL, PsycINFO, Web of Science, and Scopus. Risk of bias and applicability assessment was performed using Prediction model Risk Of Bias ASsessment Tool (PROBAST).

Results

We identified 182 potentially eligible studies from 2,259 records, and 8 papers were included in this systematic review. A wide variability in the experimental settings and characteristics of the enrolled samples emerged across studies, which probably represented the major cause for the absence of shared common predictors of violence found by the models learned. Nonetheless, a general trend toward a better performance of ML methods compared to structured violence risk assessment instruments in predicting risk of violent episodes emerged, with three out of eight studies with an AUC above 0.80. However, because of the varied experimental protocols, and heterogeneity in study populations, caution is needed when trying to quantitatively compare (e.g., in terms of AUC) and derive general conclusions from these approaches. Another limitation is represented by the overall quality of the included studies that suffer from objective limitations, difficult to overcome, such as the common use of retrospective data.

Conclusion

Despite these limitations, ML models represent a promising approach in shedding light on predictive factors of violent episodes in clinical and forensic settings. Further research and more investments are required, preferably in large and prospective groups, to boost the application of ML models in clinical practice.

Systematic review registration

[www.crd.york.ac.uk/prospero/], identifier [CRD42022310410].
Cerebellar correlates of social dysfunction among individuals at clinical high risk for psychosis
Authors: Frosch Isabelle R. , Damme Katherine S. F. , Bernard Jessica A. , Mittal Vijay A.
Published: December 2022

Introduction

Social deficits are a significant feature among both individuals with psychosis and those at clinical high-risk (CHR) for developing psychosis. Critically, the psychosis risk syndrome emerges in adolescence and young adulthood, when social skill development is being fine-tuned. Yet, the underlying pathophysiology of social deficits in individuals at CHR for psychosis remains unclear. Literature suggests the cerebellum plays a critical role in social functioning. Cerebellar dysfunction in psychosis and CHR individuals is well-established, yet limited research has examined links between the cerebellum and social functioning deficits in this critical population.

Method

In the current study, 68 individuals at CHR for developing psychosis and 66 healthy controls (HCs) completed social processing measures (examining social interaction, social cognition, and global social functioning) and resting-state MRI scans. Seed-to-voxel resting-state connectivity analyses were employed to examine the relationship between social deficits and lobular cerebellar network connectivity.

Results

Analyses indicated that within the CHR group, each social domain variable was linked to reduced connectivity between social cerebellar subregions (e.g., Crus II, lobules VIIIa and VIIIb) and cortical regions (e.g., frontal pole and frontal gyrus), but a control cerebellar subregion (e.g., lobule X) and was unrelated to these social variables.

Discussion

These results indicate an association between several cerebellar lobules and specific deficits in social processing. The cerebellum, therefore, may be particularly salient to the social domain and future research is need to examine the role of the cerebellum in psychosis.
Optimal parameter determination of repetitive transcranial magnetic stimulation for treating treatment-resistant depression: A network meta-analysis of randomized controlled trials
Authors: Li Jinbiao , Cui Liqian , Li Hao
Published: December 2022

Background

Many studies have shown the efficacy of repetitive transcranial magnetic stimulation (rTMS) in treatment-resistant depression (TRD). However, the choice of different parameters has been a challenging issue.

Methods

PubMed, Cochrane, and Embase databases were searched for relevant studies until June 20, 2022. The treatment efficacy was evaluated by the relative risk (RR) using the pairwise test for response and remission rates. Subgroup and sensitivity analyses were conducted to explore the primary outcome differences and to assess the reliability of the results.

Results

Thirty-seven trials comprising 2120 participants with TRD were included. The more efficacious interventions compared to sham controls included high-frequency left followed by low-frequency right sup-threshold (HFL-LFR-sup-rTMS, RR = 5.29, 95% CI: 1.24–22.50), high-frequency left sup-threshold (HFL-sup-rTMS, RR = 2.97, 95% CI: 1.74–5.05), low-frequency right sup-threshold (LFR-sup-rTMS, RR = 2.72, 95% CI: 1.50–4.90), low-frequency right followed by high-frequency left sup-threshold (LFR-HFL-sup-rTMS, RR = 2.71, 95% CI: 1.62–4.53), and high-frequency left sub-threshold (HFL-sub-rTMS, RR = 1.91, 95% CI: 1.18–3.10) rTMS. The estimated relative ranking of treatments suggested that HFL-LFR-sup-rTMS (84.4%) might be the most efficacious among all rTMS strategies. No treatments showed a lower acceptability than the sham control.

Limitations

Subgroup analysis was not conducted to compare the efficacy of rTMS treatment between bipolar and unipolar depression, and small-study effects possibly introduced bias.

Conclusion

Treatment with HFL-LFR-sup-rTMS, HFL-sup-rTMS, LFR-sup-rTMS, LFR-HFL-sup-rTMS, or HFL-sub-rTMS is more efficacious than the sham control. HFL-LFR-sup-rTMS and HFL-sup-rTMS may be the two best among the most efficacious rTMS treatments.

Systematic review registration

[https://www.crd.york.ac.uk/PROSPERO], identifier [CRD42022334481].
Cognitive functioning in a group of adolescents at risk for psychosis
Authors: Mohn-Haugen Caroline Ranem , Mohn Christine , Larøi Frank , Teigset Charlotte M. , Øie Merete Glenne , Rund Bjørn Rishovd
Published: December 2022

Cognitive deficits are a core feature of schizophrenia, and impairments are present in groups at-risk for psychosis. Most at-risk studies include young adults and not younger age-groups, such as adolescents. Participants are usually help-seeking individuals, even though risk factors may also be present in non-help seeking adolescents. We aim to explore cognitive functions in a group of non-help-seeking 15-year-old adolescents at risk for psychosis compared to age- and gender matched controls, including particular focus on specific cognitive domains. Hundred participants (mean age = 15.3) were invited after completing the 14-year-old survey distributed by the Norwegian Mother-, Father- and Child Study. At-risk adolescents were selected based on high scores on 19 items assessing both psychotic experiences and anomalous self-experiences. Matched controls were selected from the same sample. Cognitive functioning was assessed using the MATRICS Consensus Cognitive Battery and IQ using Wechsler’s Abbreviated Test of Intelligence. We found that the adolescents at-risk for psychosis had significantly poorer scores than controls on the composite score of the MCCB. IQ scores were also significantly lower in the at-risk group. The results highlight general cognitive deficits as central in a group of non-help-seeking adolescents at-risk for psychosis. Results indicate that the development of cognitive impairments starts early in life in at-risk groups. It is still unclear whether specific cognitive domains, such as verbal learning, are related to psychotic symptoms or may be specifically vulnerable to symptoms of depression and anxiety.
Who will treat older patients? Should medical education focus more on activities aimed at displaying positive attitudes toward older people? The prevalence of ageism among students of medical and health sciences
Authors: Podhorecka Marta , Husejko Jakub , Woźniewicz Agnieszka , Pyszora Anna , Kȩdziora-Kornatowska Kornelia
Published: December 2022

In the conditions of an aging society, a justification is found to explain the issue of the attitude of future health care workers, who are to care for elderly people in the future, toward these people, which will make it possible to predict in advance what problems related to the care of seniors may soon arise. After clarifying this issue, it will be important to distinguish the individual factors influencing this attitude in order to determine which social phenomena will require special attention. Eight hundred and three medical and health sciences students participated in the research from various fields of medical studies. A Survgo system was used, where an online questionnaire was placed and then posted in social media. Only students of medicine and healthcare facilities participated in the study. The first questionnaire contained socio-demographic questions. Then, the KOAP questionnaire and Welch's t-test were used, and finally the proprietary questionnaire on contact with seniors. Analyses were conducted using the R Statistical language. Scores on the KAOP questionnaire ranged from 122.4 to 134.57. The highest scores were shown for physiotherapy students and the lowest for pharmacy students. The highest level of attitude toward elderly was reported in students of 1st to 3rd year of study. For 4th-5th year or supplementary level students, attitude levels were decreasing. Welch's t-test showed that the level of attitude toward old people in men was significantly higher than in women. There was no significant correlation between the age factor on the quotient scale and the KOAP score. Married individuals had significantly higher KAOP scores compared to singles and those in an informal relationship. No significant differences between the study stage factor and KAOP score have been found. Those who live and/or have regular contact with the elderly were characterized by higher KAOP questionnaire scores. The attitude toward the elderly depends on many factors, such as the chosen field of study, stage of education, contact with the elderly, gender or marital status. In order to develop proper contact with seniors, the solution may be to influence modifiable factors, especially the correct education of future health care workers.
Proximity to major roads and the incidence of osteoporotic fractures in elderly women: The BONE study in Beijing
Authors: Ren Yun , Li Weishi , Chen Zhongqiang , Liu Jue , Fan Dongwei
Published: December 2022

Background

There is growing evidence to suggest that living near major roads (and suffering from the air pollution of urban streets) can have an adverse effect on bone health. However, little is known about its relationship to fractures caused by osteoporosis.

Objective

This study was designed to investigate the relationship between residents living near major roads and the incidence of osteoporotic fractures.

Methods

A retrospective cohort of 529 subjects was established based on community populations in older women aged 65–91. All participants lived in Beijing between September 27, 2007 and September 26, 2017. The distance between the residential sites of the subjects and the main roads was determined by the authors. Osteoporotic fracture diagnosis was based on medical histories and imaging examinations (DXA and X-rays). The Cox proportional hazard model was used to assess the association between traffic proximity and osteoporotic fractures, with suitable adjustments for individual and background factors.

Results

The age range of all participants was 65–91 years, with an average age of 75.8 years (and a standard deviation 6.8 years). Of these, 19 (3.59%) suffered from diabetes, and 48 (9%) had hypertension; 85 (14%) families had annual incomes below US $30,000 and 402 (76%) had received a secondary school education or higher. Nearly 25% of people lived within 50 m of a main road, while 50% lived within 300 m. Between 2007 and 2017, a total of 96 osteoporotic fractures were observed. For people living <50 m from a main road, the adjusted hazard ratio (HR) for osteoporotic fractures was 2.509 (95% CI 1.345–4.680), while it was 1.830 (95% CI 1.029–3.255) for those living at a distance of 50–300 m from a main road vs. those living further than 300 m away.

Conclusion

In this community-based cohort, living near a major road was associated with a higher incidence of osteoporotic fractures.
Comparative efficacy of exercise modalities for cardiopulmonary function in hemodialysis patients: A systematic review and network meta-analysis
Authors: Zang Wanli , Fang Mingqing , He He , Mu Liang , Zheng Xiaoqin , Shu Heng , Ge Nan , Wang Su
Published: December 2022

Background

To provide reliable evidence to exercise rehabilitation therapists and clinicians, we compared and analyzed the effects of different exercise modalities on cardiopulmonary function in hemodialysis patients using Bayesian network meta-analysis.

Methods

PubMed, OVID, Web of Science, Cochrane Library, Embase, Scopus, CINAHL, SPORT Discus, SinoMed, CNKI, Wanfang, and VIP were searched from inception to July 20, 2022. We included randomized controlled trials comparing 12 exercise modalities to improve cardiorespiratory fitness in hemodialysis patients. All statistical analysis was performed using STATA and R.

Result

A total of 82 randomized controlled trials involving 4146 maintenance hemodialysis patients were included in this study. The pair-wise meta-analysis showed that all exercise modalities had a positive effect on all indicators of cardiorespiratory capacity. The network meta-analysis demonstrated that Blood flow restriction training (BFRT), Cycle exercise (CE), Inspiratory muscle training (IMT), Combined aerobic and resistance training (CT), and Aerobic training (AT) were significantly better than usual care for 6-min walkability; Medium intensity continuous training (MICT), CT, CE, and AT were considerably better than usual care for VO2Peak; body and mind training (MBT) and CT significantly improved SBP compared to usual care; and only MBT was significantly better than usual care for DBP. Both the two-dimensional plot and the radar plot demonstrated that CT had the best combined-effect on each index of cardiorespiratory fitness. Subgroup and sensitivity analyses demonstrated the robustness of the results. The evidence was mainly “low” to “very low” for this network meta-analysis.

Conclusion

There is no one exercise that can achieve the best effect on all of the outcomes. The benefits of MBT in decreasing arterial blood pressure are unsurpassed by other exercise methods. The intervention effect of the CT is better and more stable. Electrical muscle stimulation training (MEST) can be employed in individuals who do not wish to exercise actively but may cause an increase in blood pressure. On the basis of the characteristics of different exercise types, guidelines developers, clinicians, and patients may employ them appropriately.

Systematic review registration

https://www.crd.york.ac.uk/PROSPERO/#recordDetails.
Prediction of suicidal ideation among Chinese college students based on radial basis function neural network
Authors: Liao Shiyi , Wang Yang , Zhou Xiaonan , Zhao Qin , Li Xiaojing , Guo Wanjun , Ji Xiaoyi , Lv Qiuyue , Zhang Yunyang , Zhang Yamin , Deng Wei , Chen Ting , Li Tao , Qiu Peiyuan
Published: December 2022

Background

Suicide is one of the leading causes of death for college students. The predictors of suicidal ideation among college students are inconsistent and few studies have systematically investigated psychological symptoms of college students to predict suicide. Therefore, this study aims to develop a suicidal ideation prediction model and explore important predictors of suicidal ideation among college students in China.

Methods

We recruited 1,500 college students of Sichuan University and followed up for 4 years. Demographic information, behavioral and psychological information of the participants were collected using computer-based questionnaires. The Radial Basis Function Neural Network (RBFNN) method was used to develop three suicidal ideation risk prediction models and to identify important predictive factors for suicidal ideation among college students.

Results

The incidence of suicidal ideation among college students in the last 12 months ranged from 3.00 to 4.07%. The prediction accuracies of all the three models were over 91.7%. The area under curve scores were up to 0.96. Previous suicidal ideation and poor subjective sleep quality were the most robust predictors. Poor self-rated mental health has also been identified to be an important predictor. Paranoid symptom, internet addiction, poor self-rated physical health, poor self-rated overall health, emotional abuse, low average annual household income per person and heavy study pressure were potential predictors for suicidal ideation.

Conclusions

The study suggested that the RBFNN method was accurate in predicting suicidal ideation. And students who have ever had previous suicidal ideation and poor sleep quality should be paid consistent attention to.
Racial and regional disparities of triple negative breast cancer incidence rates in the United States: An analysis of 2011–2019 NPCR and SEER incidence data
Authors: Zhang Wei , Bai Yuhui , Sun Caixing , Lv Zhangchun , Wang Shihua
Published: December 2022

Objective

Triple negative breast cancer (TNBC) is a more aggressive subtype resistant to conventional treatments with a poorer prognosis. This study was to update the status of TNBC and the temporal changes of its incidence rate in the US.

Methods

Women diagnosed with breast cancer during 2011–2019 were obtained from the National Program of Cancer Registries (NPCR) and Surveillance, Epidemiology and End Results (SEER) Program SEER*Stat Database which covers the entire population of the US. The TNBC incidence and its temporal trends by race, age, region (state) and disease stage were determined during the period.

Results

A total of 238,848 (or 8.8%) TNBC women were diagnosed during the study period. TNBC occurred disproportionally higher in women of Non-Hispanic Black, younger ages, with cancer at a distant stage or poorly/undifferentiated. The age adjusted incidence rate (AAIR) for TNBC in all races decreased from 14.8 per 100,000 in 2011 to 14.0 in 2019 (annual percentage change (APC) = −0.6, P = 0.024). Incidence rates of TNBC significantly decreased with APCs of −0.8 in Non-Hispanic White women, −1.3 in West and −0.7 in Northeastern regions. Women with TNBC at the age of 35–49, 50–59, and 60–69 years, and the disease at the regional stage displayed significantly decreased trends. Among state levels, Mississippi (20.6) and Louisiana (18.9) had the highest, while Utah (9.1) and Montana (9.6) had the lowest AAIRs in 2019. New Hampshire and Indiana had significant and highest decreases, while Louisiana and Arkansas had significant and largest increases in AAIR. In individual races, TNBC displayed disparities in temporal trends among age groups, regions and disease stages. Surprisingly, Non-Hispanic White and Hispanic TNBC women (0–34 years), and Non-Hispanic Black women (≥70 years) during the entire period, as well as Asian or Pacific Islander women in the South region had increased trends between 2011 and 2017.

Conclusion

Our study demonstrates an overall decreased trend of TNBC incidence in the past decade. Its incidence displayed disparities among races, age groups, regions and disease stages. Special attention is needed for a heavy burden in Non-Hispanic Black and increased trends in certain groups.
Electronic cigarette or vaping use among adolescents in the United States: A call for research and legislative action
Authors: Gilmore Bretton , Reveles Kelly , Frei Christopher R.
Published: December 2022

Vaping among adolescents is increasingly common and may result in poor health outcomes; however, little research has been conducted evaluating the risks of vaping among adolescents and the knowledge and perceptions that drive use. We must gain a better understanding of vaping outcomes and adolescents' perceptions while identifying potential ways to lessen or eradicate the health burdens associated with vaping. This knowledge could then inform robust educational and public health programs to prevent and mitigate vaping among youths. Health education incorporating a target populations' world view, spheres of influence, readiness, motivation, intention, and determination promotes informed decision making. There are few resources currently being allocated to the problem even though legislators and enforcement agencies are aware. We cannot simply rely on existing laws to serve as a sufficient deterrent to prevent underaged usage. Further efforts are needed in the areas of behavioral science, health education, and public policy to tackle this urgent public health concern.