bluuebunny/crossref_metadata_2025 huggingface dataset:
MODAL CONTROL OF FEEDING PROCESSES IN THE MEDIUM OF STATE SPACE AND WAVELET TRANSFORMS
Authors: Simikova Anna Alekseevna , Fedosenkov Boris Andreevich , Fedosenkov Denis Borisovich
Published: October 2019

The article presents the essential aspects of designing and operational functioning of computer-aided modal control systems, using the example of a control system for feeding processes in а mixture-producing set. The object of study is the structure of feeding devices unit and transient processes during feeding. The subjects of research are the issues of designing and creating a computer-aided modal control system ( CMCS ) which operates in the mode of tunable parametrically non-stationary in frequency transient processes ( TP ). In this case, the scalar signals of the feeding devices ( FD ) material flows are formed in terms of the state space method (in the format of the internal models “input-state-output”), and monitoring of such processes is carried out in the time-frequency wavelet medium. The latter makes it possible to analyze the processes occurring in the CMCS at a semantically transparent and information-saturated level. The parameters (pulse signal off-duty ratios) of the Fourier model for the signals of a discrete-type feeder are presented, on which the nature of the dosing process depends. A model of the feeders unit is formed in terms of the state space. The 1 D -flow rate signals and their representations in the form of time-frequency distributions ( W -maps) are considered. A new concept was developed for flow rate modal control of the feeding devices unit in the frame of the mixture-producing set by introducing the definition of parametric non-stationary state of the feeding devices internal environment that takes into account the real-time variation of the multidimensional state feedback coefficient during transients in the system and for the purpose of experimental estimation of transients parameters ( here: time constants), they are determined by flow signal distributions on W -maps. The wavelet medium used in the system deals with Cohen’s class time-frequency distributions (Wigner-Ville and Choi-Williams transformations). The combination of TP -models in terms of the state space and their representation in the Wigner distribution format allows one to evaluate, set and reassign the parameters of the internal structure of the object controlled (a separate feeder or feeding devices unit) in real time in order to achieve the effect of stabilizing the ingredients flow rate in a rated mode at pre-mixing stage. The transient modes are presented in the form of processes restoring the rated modes (the so-called reverse TP) . A procedure has been developed and described for the implementation of a modal control algorithm for the feeding process, including the technology of forced localization and relocalization of the object poles under non-stationary processes in the “Executive mechanism- FD ” system, using the example of a continuous-type feeder in a transient mode on load decrease (with a downward reverse transitional process). For this mode, the calculation of the non-stationary matrix of the modal controller is presented.
aproximación a la poética teatral de Angélica Liddell
Authors: Loureiro Álvarez Katherine Elizabeth
Published: October 2019

Angélica Liddell (Figueras, 1960) constituye una de las voces más destacables del ámbito teatral contemporáneo. Su producción teatral se centra en el dolor y es, fundamentalmente, fruto de una búsqueda personal de la verdad humana y sus aspectos más oscuros y velados. El “Teatro de la Pasión” está estrechamente ligado a la importancia de la presencia en escena del actor en calidad de “cuerpo del texto”. Se trata de un discurso metarreflexivo, aparentemente propio y espontáneo, que se caracteriza por la subversión, la fuerza expresiva, la interpelación directa al espectador y por ofrecer un amplio horizonte de significado.
Photostability of TiO2-Coated Wool Fibers Exposed to Ultraviolet B, Ultraviolet A, and Visible Light Irradiation
Authors: Tang Qi , Zhang Hui , Han Ye , Wang Dou , Wu Hailiang
Published: October 2019

This study is to investigate the role of the coating of TiO2 nanoparticles deposited on wool fibers against high-intensity ultraviolet B (UVB), ultraviolet A (UVA), and visible light irradiation. The properties of tensile and yellowness and whiteness indices of irradiated TiO2-coated wool fibers are measured. The changes of TiO2-coated wool fibers in optical property, thermal stability, surface morphology, composition, molecular structure, crystallinity, and orientation degree are characterized using diffuse reflectance spectroscopy, thermogravimetric analysis, scanning electronic microscopy, energy-dispersive X-ray spectroscopy, Fourier-transform infrared spectroscopy, and X-ray diffraction techniques. Experimental results show that the tensile properties of anatase TiO2-coated wool fibers can be degraded under the high-intensity UVB, UVA, and visible light irradiation for a certain time, resulting in the loss of the postyield region of stress–strain curve for wool fibers. The coating of TiO2 nanoparticles makes a certain contribution to the tensile property, yellowness and whiteness indices, thermal stability, and surface morphology of wool fibers against high-intensity UVB, UVA, and visible light irradiation. The high-intensity UVB, UVA, and visible light can result in the photo-oxidation deterioration of the secondary structure of TiO2-coated wool fibers to a more or less degree. Meanwhile, the crystallinity and orientation degree of TiO2 coated wool fibers decrease too.
Picturing Future Imaginaries for Innovations Towards Sustainability Transitions
Authors: Narayan Rumy
Published: October 2019

Sustainability is about the world we need but are not quite sure how to garner consensus about what it should be. As it is yet to exist, we can always imagine what it could be and design networks for this transition. Such innovation networks fueled by imaginaries could offer countless opportunities for transition incentivized through applications like tokens, available through decentralized ledger technologies (DLTs).
Les Conflits Interethniques en République Démocratique du Congo et Dans la Région des Grands Lacs Africains : Le Cas de L’ituri
Authors: Ukelo Jok Oga
Published: October 2019

Black Africa has become the theatre of everlasting war. These are wars in which Africans massacre their brothers and plunder the natural resources of their continent. We can cite the cases of the Bakongo and the Bangala in the Congo Brazzaville or the Tutsis and the Hutu in Rwanda. In this article the questions surrounding the interethnic conflicts in the Democratic Republic of Congo, via a case study of the conflict between the Hema and Lendu in the Ituri region, are explored. The main thrust of the article is that the concept of good governance is linked to a sustainable developmental strategy and that this is the only way to reach peace in this geographical area.[...]
PENINGKATAN HASIL BELAJAR BAHASA INGGRIS MENGGUNAKAN MODEL TUTORIAL BERBASIS KOMPUTER
Authors: Andiriyanto Ach.
Published: October 2019

Mengetahui peningkat hasil belajar bahasa Inggris mahasiswa  menggunakan model tutorial berbasis komputer merupakan tujuan dari penelitian ini. Subjek Penelitian ini adalah mahsiswa di Universitas Wiraraja Sumenep. Dengan penelitian ini diharapkan nantinya dapat menghasilkan variasi pembelajaran yang effektif yang dapat  memotivasi mahasiswa dalam pembelajaran bahasa inggris khususnya pada topik tenses.Penelitian ini meggunakan metode penelitian tindakan kelas menggunakan pendekatan metode kuantitatif.  Dalam pelaksanaannya menggunakan dua siklus, yang mana tiap siklus tediri atas empat tahapan “perencanaan, pelaksanaan, pengamatan dan refleksi”. Teknik penelitian yang digunakan padapengambilan sample adalah random sampling. Instrument yang digunakan tes pilihan ganda tertulis.Ditinjau dari fokus penelitian diperoleh hasil bahwa proses pembelajaran bahasa Inggris khususnya pada bahasan tenses menggunakan model tutorial berbasis komputer bisa terlaksana dengan maksimal dan lancar serta terbukti efektif untuk meningkatkan hasil belajar dan motivasi mahasiswa. Selain itu perkuliahan menggunakan model tutorial berbasis komputer juga memiliki dampak positif yaitu bisa menumbuhkan semangat mahasiswa untuk lebih mandiri, kreatif, disiplin waktu, dan lebih aktif saat proses pembelajaran dikelas.Hasil dari penelitian ini menunjukkan bahwa penerapan model pembelajaran tutorial berbasis komputer ini mampu meningkatkan ketuntasan belajar mahasiswa sebesar 34,20% pada siklus I, sedangkan pada siklus II naik 23,90 % yaitu menjadi 88,10%. Nilai rata-rata kelas juga mengalami peningkatan sebesar 11,8 poin pasa siklus pertama dan 10,7 poin pada siklus kedua. Hasil posttest menunjukkan bahwa 88% mahasiswa mendapat nilai >70, jadi kondisi ini sudah memenuhi Indikator   keberhasilan  penelitian yang sudah ditetapkan yaitu 75 % mahasiswa telah mencapai  nilai minimal 70.
MEMBANGUN MODAL SOSIAL PADA MASYARAKAT DI ERA GLOBALISASI
Authors: Prijambodo Raden Firman Nurbudi , Mahatmaharti Agung Kesna
Published: October 2019

Saat ini perkembangan kemajuan jaman mempengaruhi roda perkembangan pembangunan bangsa Indonesia. Era globalisasi tidak dapat dipungkiri telah sedikit banyak menggeser tatanan perilaku warga negara di dalam pergaulan bermasyarakat. Masyarakat Indonesia yang plural dengan kenyataan dimasukkannya Bhinneka Tunggal Ika sebagai semboyan bangsa, membuat bangsa ini harus menjaga rasa sosial yang tinggi. Kenyataannya pada kehidupan sehari-hari telah berlaku sikap toleransi tersebut.Keragaman bangsa Indonesia perlu dijaga keberadaannya dengan menjaga nilai-nilai etika sosial yang selama ini dijalankan. Kehidupan sosial bermasyarakat dapat dituangkan dalam berbagai macam bentuk sikap dan kegiatan. Setiap kegiatan kemasyarakatan, tidal terlepas dari modal sosial. Modal sosial diperlukan untuk menguatkan terbentuknya nilai-nilai bermasyarakat.Masyarakat yang menghargai keberadaan modal sosial sebagai pembentuk ikatan tersebut akan menyadari betapa pentingnya peran modal sosial. Melalui modal sosial yang terjalin di antara mereka maka akan melancarkan terwujudnya keinginan-keinginan mereka dalam bentuk kegiatan yang positif bagi masyarakat dan negara.
PENDEKATAN SCIENTIFIK DALAM PENERAPAN KKNI PADA PEMBELAJARAN IPS SD
Authors: Sari Tita Tanjung , Hanip Rival
Published: October 2019

Kurikulum 2013 seolah menjadi babak baru dalam usaha kita untuk memperbaiki sistem pendidikan nasional. Dalam kurikulum 2013, guru diharap melakukan pembelajaran secara holistik dan terpadu untuk mengembangkan seluruh potensi peserta didik. Kekhasan kurikulum 2013 dalam pembelajaran terdapat pada penggunaan pendekatan ilmiah sebagai alat untuk mempercepat tercapainya tujuan pembelajaran. Pendekatan ilmiah (scientific approach) dianggap sebagai salah satu cara menuju perkembangan dan pengembangan komponen kemampuan siswa, baik secara kognitif, afektif, maupun psikomotor dalam proses kerja ilmiah. Pada pembelajaran scientific tidak hanya terfokus pada proses eksplorasi, elaborasi, dan konfirmasi, namun juga peserta didik dilatih untuk terbiasa mengamati, bertanya, bernalar, berkeskperimen atau mencoba, mempresentasikan atau mengkomunikasikan dan berkembang sampai dengan mengumpulkan data, mengolah data, mengkomunikasikan hasil kerja, inovasi produk dan proses penciptaan produk. Pada dasarnya inti dari scientific thinking adalah mengajak peserta didik untuk terbiasa berfikir secara ilmiah dan terbiasa mengkomunikasikan sesuatu berdasarkan hasil pengamatan, data, dan fakta. Selain itu scientific thinking menekankan untuk melakukan pembelajaran secara luas, tanpa terbatas oleh dinding dinding kelas. Karena belajar bisa dilakukan kapan saja dan dimana saja, baik dilingkungan sekolah maupun dalam masyarakat luas. Kurikulum 2013 juga mengajak guru untuk menjadi mediator, fasilitator, dan evaluator yang menjadi jembatan transfer ilmu. Pembelajaran harus berpusat pada anak, karena dalam hal ini, anaklah yang harus mengeplorasi segenap kemampuannya dengan cara mengamati dan mencoba sementara guru menjadi salah satu sumber belajar bukan satu-satunya sumber belajar peserta didik, sehingga siswa diarahkan untuk aktif bergerak mencari informasi dan membangun mengetahuannya sendiri. Namun guru harus tetap memperhatikan setiap perkembangan siswa baik secara kognitif, afektif, dan psikomotor. Sehingga siswa tidak hanya baik secara hard skill tetapi juga melatih kematangan soft skill.
CARD SORT MELALUI ACTIVE LEARNING UNTUK MENINGKATKAN KEAKTIFAN SISWA PADA PEMBELAJARAN IPA TERPADU
Authors: Syarifah Habibah Asy , Azizah Lutfiana Fazat , Meita Nisfil Maghfiroh
Published: October 2019

Penelitian ini bertujuan untuk meningkatkan keaktifan siswa kelas VII-Unggulan MTs Sumber Payung dengan penerapan Card sort melalui Active Learning. Subjek penelitian ini berjumlah 25 siswa. Jenis penelitian yang digunakan yaitu Penelitian Tindakan Kelas (PTK) dengan dua siklus. masing-masing siklus dengan dua pertemuan. Siklus penelitian diadopsi dari Kemmis dan MC Taggart yang meliputi tahap perencanaan, pelaksanaan, pengamatan dan refleksi. Teknik pengumpulan data berupa lembar observasi keterlaksanaan pembelajaran dan lembar observasi keaktifandianalisis secara deskriptif kuantitatif dengan persentase. Hasil penelitian munujukkan data sebagai berikut: 1) Keterlaksanaan pembelajaran meningkat setiap siklusnya dengan persentase pada siklus I91,33% dan siklus II 93,88% dengan kategori sangat sesuai RPP/Sangat baik; 2) Keaktifan siswa mengalami peningkatan pada setiap siklusnya, dengan persentase siklus I 58% dan siklus II 66,5% dengan kategori keaktifan sedang.
IMPLEMENTASI MODEL PEMBELAJARAN CTL (CONTEXTUAL TEACHING AND LEARNING) DALAM PEMBELAJARAN BAHASA INDONESIA DI SEKOLAH DASAR
Authors: Sitiasih Ni Made
Published: October 2019

Penelitian ini dilaksanakan di SD Negeri 2 Peguyangan di Kelas III    semester II Tahun Pelajaran 2017/2018 dengan tujuan untuk mengetahui apakah Penggunaan  model pembelajaran CTL (Contextual Teaching And Learning) dapat meningkatkan prestasi belajar Bahasa Indonesia  siswa kelas III  semester II tahun Pelajaran 2017/2018. Metode pengumpulan datanya adalah tes prestasi belajar dengan metode analisis datanya adalah deskriptif kuantitatif karena data yang diperoleh masih berbentuk angka. Hasil yang diperoleh dari penelitian ini dapat dijabarkan sebagai berikut: untuk data awal  63,5    data siklus I terjadi peningkatan 66,73 dan pada siklus II meningkat menjadi 80,19. Setelah dilakukan analisis dari data yang ada maka diperoleh kesimpulan Penggunaan model pembelajaran CTL( Contextual Teaching And Learning) jika dilaksanakan dapat meningkatkan prestasi belajar siswa.
PELAKSANAAN SUPERVISI KOLABOTARIF UNTUK MENINGKATKAN KUALITAS PENGAJARAN GURU SEKOLAH DASAR
Authors: Sumantri Ni Made
Published: October 2019

Penelitian Tindakan Sekolah ini dilaksanakan di SD Negeri 2 Peguyangan Kecamatan Denpasar Utara.  Penelitian ini dilaksanakan karena melihat prestasi siswa Kelas IV SD Negeri 2 Peguyangan dalam mata pelajaran IPA  sampai tahun pelajaran 2017/2018 masih belum baik walaupun ditetapkan standar kelulusan dengan nilai minimal 4,01, terbukti masih banyak siswa yang belum lulus sehingga diadakan ujian ulangan. Hasil supervisi guru SD Negeri 2 Peguyangan tanggal 1 Agustus 2018 masih ditemukan adanya guru yang belum maksimal dan masih dilihat lemahnya kualitas pengajaran guru. Bertitik tolak dan hasil-hasil penelitian yang menggambarkan kondisi di SD Negeri 2 Peguyangan, yaitu dimana masih lemahnya kualitas pengajaran guru, kualitas supervisi pengajaran kepala sekolah, sehingga berdampak pada hasil belajar siswa. Berdasarkan uraian di atas juga tampak bahwa hasil belajar dipengaruhi oleh kualitas supervisi pengajaran kepala sekolah dan kualitas pengajaran guru. Untuk itu perlu kiranya dikaji tentang “Model Pendekatan Supervisi untuk Meningkatkan Kualitas Pengajaran Guru-guru pada SD Negeri 2  Peguyangan Tahun Pelajaran 2018/2019”. Kualitas pengajaran guru dalam penelitian ini difokuskan pada kemampuan guru dalam menggunakan model kooperatif tipe STAD pada kurikulum2013.  Pada siklus I terdapat 1 orang guru yang masih mendapatkan nilai rendah sehingga pada secara kuantitatif dan kualitatif setelah kedua siklus dilaksanakan maka 1 orang guru Kelas IV SD Negeri 2 Peguyangan Berhasil (100%) meningkatkan kualitas mengajar dengan peningkatan 50%.
Judicial protection and interpretation of the right to take part in a referendum – an overview of the jurisprudence of the Hungarian Constitutional Court and the Supreme Court
Authors: Erdös Csaba
Published: October 2019

This paper gives an overview of the jurisprudence of the Hungarian Constitutional Court and the Supreme Court regarding the right to take part in a referendum. This is a fundamental right of political participation, not unlike the right to vote and to stand as a candidate in parliamentary elections. It being a genuine fundamental right, the Constitutional Court interpreted its authentic meaning and stipulated the most important constitutional requirements related to this right. One of the most important requirements was the establishment of a system of remedies, where the final decision on the certification of a question proposed for a referendum must be taken by the Constitutional Court. Parliament fulfilled this legislative requirement and since 1998 the Constitutional Court has controlled the constitutionality of the decisions taken by the National Election Committee on the certification of the referendum questions proposed. The 2013 Act on referendum transferred this competence to the Supreme Court. Since then, the Constitutional Court shall only decide referendum-cases which were submitted with the so-called ‘direct constitutional complaint’, an extraordinary type of constitutional remedy. The present paper compares these two remedy systems introduced for the protection of the right to take part in a referendum.
The administrative justice in the Czech Republic – changes and expectations
Authors: Potěšil Lukáš
Published: October 2019

This article deals with the changes that were made and with possible expectations in the field of administrative justice which can be observed on the example of (not only) the Czech Republic. To this end, the contribution focuses, first, on the purpose of the administrative justice as such and on its history and development. Then it gives consideration to the current stat and form of the legal framework of the administrative justice in the Czech Republic. On this basis, the last part of the contribution deals with the changes which have been made in the administrative justice as well as with possible expectations that may be placed on the administrative justice, going hand in hand with its possible changes in the future.
Zasada nullum crimen sine lege w kontekście przestępstw stypizowanych w art. 256 § 1 k.k.
Authors: Scheffler Tomasz
Published: October 2019

The paper presents interpretations of the content of the legal principle of nullum crimen sine lege and the influence of this principle on legal characterisation of crime of public propagation of a fascist or other totalitarian governance system and crime of public agitation to hatred based on national, ethnic, racial or religious differences or for reason of a lack of any religiousdenomination. In the author’s opinion, the most difficult problem in the case of crimes typified in Art. 256 § 1 of Polish Penal Code lies in that many layers consider the legal principle of nullum crimen as a commonplace. In the paper, there are several cases presented of adjudications of the Polish Supreme Court relating to what considerations of the legal principle of nullum crimen may cause so that we can obtain clear views on the problem.
PENGELOLAAN PEMBELAJARAN PENDIDIKAN ANAK USIA DINI DI KB CERDAS KECAMATAN BATU HAMPAR KABUPATEN ROKAN HILIR
Authors: Denico Ahmad
Published: October 2019

The research was conducted at KB Smart Rokan Hilir Hamper Stone with data sources consisting of managers, educators, and students in Smart KB. The purpose of this study was to explain the management of early childhood education (PAUD) learning in Smart KB in Batu Hampar District, Rokan Hilir Regency. Data collection techniques in this study were interviews, observation, and documentation. The results of this study are (1) PAUD learning syllabus in the form of semester planning, weekly planning, and daily/meeting planning. Planning is done by paying attention to the level of development, needs, interests, and characteristics of students, and aspects of development include religious and moral, motoric, cognitive, language and social-emotional values. (2) The implementation of learning in Smart KB starts with (a) happy morning, (b) habituation activities, (c) transition, (d) environmental footing, (e) footing before playing, (f) footing during playing, (g) footing after playing, (h) introduction of prayer, and (i) closing. The implementation of learning uses the method of playing while learning through center class learning with the Beyond Center and Circle Time (BCCT) approach, and the question and answer method, stories, role-playing or direct field practice. Activities are carried out in a comfortable, safe, clean and healthy playing environment. (3) Assessment of learning in Smart KB is done by observing at any time not during the KBM until the learning is finished. through observation, recording anecdotes, and portfolios.
A social change theory for interpretation of the migration flows of the Bangladeshi labor emigration
Authors: Shаhanaz P.
Published: October 2019

The special features of the Bangladeshi emigrant work force have been considered. The explanation of the reason under the theoretical framework of social change has been presented, on which the neoclassical theory of migration, and, also the push and pull factors theory, cannot clarify the specific distribution of migrants, which is observed. The neoclassical theory of migration has been analyzed, which supposes, that economic factors should determine the choice of a destination country by a emigrant, and it shows how the theory would predict, that the distribution of emigrants should be correlated to the relative average income of the hosting countries. Therefore, the theory is not respected in the case of the Bangladeshi emigration. The network model of migration, even though it partially fixes this problem, can still not explain the emergence of enclaves of Bangladeshi citizens in hosting countries.

The theory of social changes, with some modifications originating from the network approach and the “governmentality” approach, might however explain the distribution of Bangladeshi emigrants abroad, and it has been assumed, that this theoretical development sheds light on the studied problem and its causes. According to this theory, the Bangladeshi emigration is one part of a global process, which creates a global civilization from a number of previously independent societies. A consequence of this theory is that the flows of migrants should more or less follow the waves of development of a globalised society, and, therefore, that it should be possible to measure modifications in the trend of globalisation by measuring the variation in the flows of migrants, or in their distribution across regions.
To the question of the methodic of universities’ scientific potential appreciation
Authors: Znamenskiy D.
Published: October 2019

The development issues of the scientific potential of higher education as an important component of the national scientific and technological system of any country has been considered. The main purpose of the study is to develop, substantiate and test methods for assessing the scientific potential of universities. The main method of research is a system-dynamic approach to the study of scientific potential.

The concept of “scientific potential of higher education” has been clarified. It seems reasonable, that the modern mission of higher education, both in Russia and in the world, is to create and further develop a unified high-level educational system, capable not only of training personnel for certain sectors of the real sector of the economy, but also to produce new knowledge, i.e. to ensure high-quality scientific and technological progress in these sectors.

An original method of assessing the scientific potential of higher education has been developed, and its approbation is the main empirical result of the study. The essence of this method lies in the consistent estimation of factors of formation of the scientific potential (initial assessment) and the forms of its realization (secondary assessment), and also in the comparison of the indices of the secondary and primary evaluations (summative evaluation). The obtained results allow us to develop a strategy for the development of scientific potential, depending on the level of effectiveness of its implementation.

The applied value of the research results is determined by the prospects of their application in the process of development of state policy for the development of research activities in higher education. In addition, the proposed methodology can be used by University leaders, who have set themselves the goal of building scientific capacity and integration into the national scientific and technological system and international scientific cooperation.
Strategic and statistical analysis of regional socio-economic development in the conditions of the digital environment
Authors: Aleshnikova V. , Burtseva T. , Shadiev H. , Gubareva A.
Published: October 2019

Тhe creation and development of the digital economy in the regions of Russia is a new factor in their socio-economic development. This should be reflected in near future in the strategies of socio-economic development of regions. In the Russian Federation, at present, for developing and evaluating the implementation of the socio-economic development strategy of the region, a universal methodology has not been developed, and the standard approaches for implementing strategic planning have been adapted from the management of corporate structures.

The purpose of the article is to test the methodology of statistical evaluation of the socio-economic development of the region in the digital environment. The methodological basis of the study are: the general statistical method of dynamic standards, index and coefficient analysis, the method of pairwise comparisons. The scientific novelty of the presented results are the author’s methodological developments: the system of indicators of the socio-economic development of the region in the digital environment and the regulatory assessment model. The practical significance of the research results lies in the possibility of applying the author’s assessment methodology for monitoring regional development strategies.

The creation of integral statistical measures (models) for monitoring traditional and new factors of the region’s development will provide solutions to their quantitative assessment, allow clarify both the planning and implementation stages of the region’s shortcomings and problems, ensure the implementation of the principle of integrated socioeconomic development of the region, contribute to enhancing the consistency of the objectives of regional development strategies, it will allow diagnostics of the development of the digital economy and develop new strategic orientations at the regional level, which in turn will make it possible to develop organizational mechanisms for involving people in the region in resolving issues of territorial strategic development.
High Resolution Photoelectron Spectroscopy of Cryogenically-Cooled NO3ˉ
Authors: Babin Mark , DeVine Jessalyn , Stanton John F. , Neumark Daniel , DeWitt Martin
Published: October 2019

High-resolution anion photoelectron spectra of cryogenically cooled NO3ˉ anions obtained using slow photoelectron velocity-map imaging are presented and provide new insight into the vibronic structure of the corresponding neutral radical. A combination of improved spectral resolution, measurement of energy-dependent intensity effects, temperature control, and comparison to theory allows for full assignment of the vibronic features observed in this spectrum. We obtain a refined electron affinity of 3.9289(14) eV for NO3. Further, the appearance of Franck-Condon forbidden transitions from vibrationally cold anions to neutral states with excitation along the NO3 v4 mode confirms that these features arise from vibronic coupling with the excited state of NO3 and are not hot bands as has been suggested. Together, the suite of experimental and simulated results provides clear evidence that the v3 fundamental of NO3 resides near 1050 cm−1, addressing a long-standing controversy surrounding this vibrational assignment.
Benchmarking Electronic Structure Methods for Accurate Fixed-Charge Electrostatic Models
Authors: Zhou Alex , Schauperl Michael , Nerenberg Paul
Published: October 2019

The accuracy of classical molecular mechanics (MM) force fields used for condensed phase molecular simulations depends strongly on the accuracy of modeling nonbonded interactions between atoms, such as electrostatic interactions. Some popular fixed-charge MM force fields use partial atomic charges derived from gas phase electronic structure calculations using the Hartree-Fock method with the relatively small 6-31G* basis set (HF/6-31G*). It is generally believed that HF/6-31G* generates fortuitously overpolarized electron distributions, as would be expected in the higher dielectric environment of the condensed phase. Using a benchmark set of 47 molecules, we show that HF/6-31G* does not uniformly overpolarize molecules and in some cases even leads to molecular dipole moments that are lower than experimental gas phase measurements. We further demonstrate that using computationally inexpensive density functional theory (DFT) methods, together with appropriate augmented basis sets and a continuum solvent model, can yield molecular dipole moments that are both more strongly and more uniformly overpolarized. These data suggest that these methods – or ones similar to them – should be adopted for the derivation of accurate partial atomic charges for next-generation MM force fields.
Cancer Cells Possess Different Isotopic Enrichment
Authors: Little Reginald , Uziel Orit
Published: October 2019

Although the dynamics of telomeres during the life expectancy of normal cells have been extensively studied, there are still some unresolved issues regarding this research field. For example, the conditions required for telomere shortening leading to malignant transformation are not fully understood. In this work, we mass analyzed DNA of normal and cancer cells for comparing telomere isotopic compositions of white blood cells and cancer cells. We have found that the 1327 Da and 1672 Da characteristic telomere mass to charge cause differential mass distributions of about 1 Da for determining isotopic variations among normal cells relative to cancer cells. These isotopic differences are consistent with a prior theory that replacing primordial isotopes of 1H, 12C, 14N, 16O, 24Mg, 31P and/or 32S by nonprimordial, uncommon isotopes of 2D, 13C, 15N, 17O, 25Mg and/or 33S leads to altered enzymatic dynamics for modulating DNA and telomere codons towards transforming normal cells to cancer cells. The prior theory and current data are consistent also with a recently observed non-uniform methylation in DNA of cancer cells relative to more uniform methylation in DNA of normal cells.
Tropoelastin-Inspired, Non-Ionic, Self-Coacervating Polyesters as Strong Underwater Adhesives
Authors: Narayanan Amal , Menefee Joshua , Liu Qianhui , Dhinojwala Ali , Joy Abraham
Published: October 2019

Inspired from the one-component self-coacervation of tropoelastin and mussel foot protein-3s, we created the first non-ionic, single component coacervates that can coacervate in a all ranges of pH (acidic to basic) and wide range of ionic strengths with degradability, rapid curing and strong underwater adhesion. In contrast to the complex coacervates, these ‘charge-free’ coacervates are potential candidates as tissue adhesives and sealants, adhesives for sensor attachment to wet skin, and as sprayable adhesives. Their potential use in the clinic arises from their enhanced stability to changes in external conditions, cytocompatibility, biodegradability and modular nature in incorporating various functional groups and crosslinkers.
The Conserved Positive Charge in the Transmembrane Domain of HIV Gp41 Contributes to Its Intrinsic Preference for Trimerization
Authors: Reichart Timothy , Leaman Daniel , Sands Daniel , Zwick Michael , Dawson Philip
Published: October 2019

The transmembrane (TM) domain of HIV glycoprotein gp41 anchors the envelope (Env) spike in the viral membrane and is highly conserved. The mid-span arginine 696 is particularly conserved, and the only other residue found in this position is lysine. Seeking to examine the role of this conserved positive charge in the structure and function of the gp41 TM domain, we synthesized a series of peptides corresponding to this region. Analysis of the peptides in a previously validated fluorescence assay in model membranes showed that the native TM domain is trimeric. Peptides in which the intramembrane arginine was mutated to alanine showed significantly lower trimerization propensity. In contrast, this mutation in the context of infectious pseudovirus caused only modest decreases in viral stability and infectivity. We propose a model to explain the importance of this charge to gp41 structure and to HIV infection.
Evaluation of some trace elements status in females type 1 diabetics patients and its relationship with oxidative stress
Authors: Seenaa kadhum Ali  , Elham Abed Mahdi  , Zinah Kadhim Kareem  , Mohanad Kadhim  Ali  , Ayad  Kadhim Ali
Published: October 2019

Disorders of trace elements in diabetic patients with type 1 are possibly led to glucose metabolism disturbance and increased oxidation, which may promote the development of diabetes and insulin resisting. We aim to clarify the role of the serum level of zinc (Zn), copper (Cu), cobalt (Co), iron  (Fe), Zn/Cu ratio and their relations with the degree of oxidative stress in females   T1D. The study included 30 healthy women and 54 women   with insulin-dependent diabetes. Serum levels of trace element have determined by atomic absorption spectrophotometer.  Results showed a decrease levels of Cu, Fe,  Zn and MDA in diabetes patients compared to controls (p <0.000), (p < 0.000)  (p< 0.001) (p <0.001) correspondingly. Significance in correlations amid Zn and age (r= -0.449, p <0.032), significance in correlations among Co in addition to age (r= -0.434, p <0.038) with significances in correlation amid Fe and MDA (r= 0.024, p <0.366).
Development of biodegradable scaffolds loaded with vancomycin micropartricles for the treatment of osteomyelitis
Authors: Souvik chakraborty  , Gowda D V  , Vishal Gupta N
Published: October 2019

In this present research work, the development of biodegradable scaffolds loaded with Vancomycin micropartricles was carried out for the treatment of Osteomyelitis. Characterization Vancomycin Loaded microparticles and evaluation of the microparticles loaded scaffolds and also to carry out In-vitro release studies. Vancomycin hydrochloride microparticles were prepared with the help of double emulsion method. HPMC and Polaxomer 407 has been taken as the main polymers for the preparation of the microparticles. Chitosan was taken as the major polymer for the preparation of scaffolds for its greater biocompatibility and biodegradability. The preparation was done with the help of the solvent casting method. The formulation was taken for further characterization and evaluation studies. Fourier-Transform Infrared Spectroscopy and Differential scanning calorimetry were carried out for the pure vancomycin drug, and the chitosan polymer X-ray diffraction was carried out to check the crystallinity of the prepared scaffolds. The particle size, zeta potential and polydispersity index for vancomycin loaded microparticles were found to be 577.0±102.5 nm, 1624 mv and 0.254. The maximum and sustained release rate of the drug was found to be 95.6±0.478, at 16th Hr. By taking all the reports, a conclusion can be drawn that, the formulated VLM biodegradable scaffolds will show burst release at the initial time of administration, which is essential for the wound healing activity and will be sustained throughout the process of treatment of osteomyelitis.
A study to assess the benefits of awareness programme on mammary gland self-observation to women residing at mappedu
Authors: Bhuvaneshwari G  , Vidhya G  , Yasmin banu  , Jothimeena  , Kalaiselvan
Published: October 2019

Mammary gland self-observation is still suggested as a universal reach. Mammary gland health awareness permits for early disclosure of any malformation. Mammary gland self-observation proceed to be suggested by physical protection practitioner because it is free of cost, easy, require small mechanics and teaching is workable. In the current review, a descriptive research design was handed down to execute the objectives of the study. The review was organized in Mappedu rural village. In the current review, the representative consists of 100 women. Self-design questions on knowledge about mammary gland self-observation have developed to learn the representative. Detailed and a prior census have being to examine the statistics.5(5%) women experiences adequate learning regarding mammary gland self-observation. 59(59%) women experience moderate learning regarding mammary gland self-observation. 36(36%) women experiences inadequate learning regarding mammary gland self-observation. This research shows that the organized education on awareness programme was successfully expanded the knowledge of women in Mappedu regarding mammary gland self-observation.
A study to assess the knowledge of Karaya powder application on diabetic wound healing among diabetic mellitus patients
Authors: Tamilselvi  , Nivitha  , Priya  , Monika
Published: October 2019

Diabetes mellitus is a serious debilitating longtime illness that grows in nearly 5% of the world’s peoples. People with this illness have a shortage of insulin or lessen capacity to use insulin; the hormone controlled blood glucose level. The study aims to assess the Karaya powder application among diabetic mellitus clients. The study was conducted in Mappedu village with 60 samples. The data was collected by using Structure interview questionnaires on Karaya powder. The result revealed that extract has significant effect increase knowledge on Karaya powder application on diabetic wound healing among diabetic clients.
Effect of topically applied nimodipine on the intraocular pressure on ocular normotensive and betamethasone-induced hypertensive eyes in rabbits
Authors: Waleed K. Abdulsahib  , Osama Q. Fadhil  , Hussam H.Tizkam
Published: October 2019

Glaucoma is a leading cause of irreversible blindness worldwide. Lowering intraocular pressure (IOP) is the only strategy documented to delay the appearance and retard the progression of vision loss. The present investigation was conducted to evaluate the effect of topical nimodipine (0.5%) drop on IOP of both normotensive and induced -hypertensive eyes in rabbits. Thirty six rabbits were included in the present study .Two groups (each group contains 6 rabbits) were used to evaluate the effect of nimodipine, one as a normotensive group and the other for induction of hypertensive.  Nimodipine ophthalmic solutions were instilled twice daily for 7 days in both normotensive and induced -hypertensive eyes (that induced by weakly subconjunctival injection of 0.7 ml of betamethasone suspension for 4 weeks). On the other hand another two groups were used to evaluate the effect of (twice daily instillation for 7 days) of Timolol and distilled water (DW).  IOP measured by Schiotz tonometer daily at about the same time (9.0 am) to avoid IOP diurnal fluctuation. The main findings of the present study were the followings: Nimodipine (0.5%) was very effective in lowering IOP in both normotensive and ocular hypertensive rabbits. Mean IOP decreased after one day of nimodipine instillation by (1.5 ± 0.43 mmHg) in normotensive eyes and by (4.5± 1.45 mmHg) in hypertensive eyes. A significant results (P ≤ 0.05) were obtained when compared the results of nimodipine with DW (as a negative control group), on the other hand no significant differences were obtained when compared with that of Timolol (as a positive group). The results obtained in this study provide experimental evidences for the effectiveness of nimodipine (0.5%) ophthalmic solutions in the reduction of IOP. In addition to above nimodipine in   applied doses were found to have tolerable ocular hypotensive effect.
Anti-hypercholesterolemic agent from Indonesian rice bran
Authors: Syaikhul Aziz  , Elfahmi  , Andreanus Andaja Soemardji  , Sukrasno
Published: October 2019

This research was conducted to determine the total oryzanol content of various extracts and bioassay-guided isolation of active anti-hypercholesterolemic agent from Indonesian rice bran. Hot solvent extraction was done by reflux method using single and binary solvents, namely hexane, chloroform, ethyl acetate, dichloromethane, isopropanol, acetone, hexane-ethyl acetate (1:1, v/v), hexane-isopropanol (1:1, v/v), and chloroform-ethyl acetate (1:1, v/v). TLC densitometric was used to quantitatively analyze the total oryzanol content in various extracts. The hexane extract was selected for fractionation and evaluated for their anti-hypercholesterolemic activity. The structure of an isolated compound was determined on the basis of NMR and Mass spectroscopy. The total oryzanol content was obtained using various solvents ranging from 27.92 to 43.59 mg/100g rice bran, in which hexane extract showed the highest amount (43.59 ± 3.36 mg/100g rice bran). β-sitosterol has been isolated from rice bran hexane extract, which shows a significant decrease in serum total cholesterol level. In summary, hexane is the best solvent to extract oryzanol compound using reflux method, and β-sitosterol was suspected to be responsible for anti-hypercholesterolemic activity in addition to existing compound such as oryzanol that contained in the rice bran.
MRSA as a causative factor for ecthyma gangrenosum: a rare case report
Authors: Kiran Madhusudhan  , Madhusudhan
Published: October 2019

Ecthyma gangrenosum is a skin manifestation of Pseudomonas aeruginosa in immunocompromised individuals. Here we report a case of a 64-year-old diabetic female with Ecthyma gangrenosum lesions on both lower limbs, admitted for surgical debridement. Pus culture taken during surgery showed growth of Methicillin-resistant Staphylococcus aureus. The patient was started on appropriate antibiotics with reasonable glycemic control using parenteral insulin. The patient responded well to the above treatment and was discharged.
Effect of probiotic and prebiotic in the formulation and elaboration of sausage as an alternative of consumption
Authors: Mosquera C  , Donoso E  , Valenzuela Y M  , Arizaga R  , Ahmed El Salous
Published: October 2019

In Ecuador, sausages are one of the most commonly used in typical foods, but traditionally these have only been beef, pork and chicken, which in turn do not contain any health benefits, on the contrary, their limited consumption is recommended. This research aims to provide the market with a new nutritional alternative that increases the variety of existing products with the difference that these sausages have an added value that are probiotics and prebiotics. To obtain a sausage formulation, variations were made in the percentages of the ingredients that were used, obtaining 3 treatments. The most popular treatment was determined by means of a sensory panel made up of 50 people, resulting in treatment 3 being the most accepted. A corresponding analysis was carried out whose result gave the presence of lactobacillus with a value of 8.8 x 108, proteins: 17.64% total fats: 26.48% cholesterol: 29.34 mg Carbohydrates: 0.82 mg / 100g dietary fiber: 3.17, the caloric intake of the sausage was 312 kcal, sodium: 495.23 mg / 100g, starch: 0.31% and according to the study of shelf life in refrigeration at 5 ° c the maximum time of consumption of the product is 22 days.
Effect of positioning on physiological parameters on low birth weight preterm babies in neonatal intensive care unit
Authors: Alice Jeba J  , Senthil Kumar S  , Shivaprakash sosale
Published: October 2019

Preterm infants are babies who are delivered before the completion of 37 weeks gestation period. They are born with immature functioning of the brain. In  Neonatal Intensive Care Unit (NICU), these infants receives many environmental stimuli, and their comfort will be disturbed. These various sensory stimulus received in NICU influence the functional and neurodevelopmental outcome of these infants and also their quality of life. So this study was intended to evaluate the axillary temperature, heart rate, respiratory rate and oxygen saturation level of these infants prior to nesting and after nesting at the 60th minute. Forty preterm infants who fulfilled the criteria of selection were included in the study by simple random sampling and segregated into case and control groups by blocked randomization. Data was collected and recorded. The temperature was recorded by a digital thermometer, respiratory rate was counted by the number of times the infants' chest rises, heart rate and oxygen saturation readings from the pulse oximeter. The result of the study showed that there was statistically significant effect of nesting at 60th minute, temperature (t=5.03966,p<0.05), respiratory rate(t= -2.13,p<0.05) and heart rate (t=-2.59766,p<0.05). But the effect was not significant on oxygen saturation level (t=1.2,p=0.238).  Hence this study result supports the use of nesting in NICU.
Evaluation of grape seed extract (Vitis vinifera) as a crosslinker on the stability of dentine collagen in total-etch adhesive systems: An in-vitro study
Authors: Dennis D  , Fenika Maitari  , Trimurni Abidin  , Wandania Farahanny
Published: October 2019

The bond strength between resin-dentine is determined by the integrity of collagen, dentine and resin monomers. The susceptibility of the dentine bond results from the instability of the bonding structure that adheres to the bonding material. This can be achieved by using collagen cross-linker, synthetically and naturally in dentine substrates which are effective in protecting collagen fibrils from degradation, as proanthocyanidine. The aim of this study was to see the effect of grape seed extract as a crosslinker on the stability of dentine collagen and see the differences between groups. This study used 27 fresh premolars or third molars which were divided into 3 groups, namely group I giving grape seed extract 6.5%, group II giving chlorhexidine 2%, and group III only giving bonding ingredients. Samples were analyzed using SEM with 1000x magnification.  Data was analyzed using the kappa statistic, Kruskal-Wallis, dan Mann-Whitney. The result of the study significant differences between treatment groups (P <0.05), the 2% chlorhexidine group showed the highest value compared to the grape seed extract group and without treatment. Grape seed extract can be used as an alternative to chlorhexidine as a crosslinker to maintain bone strength of the composite restoration