bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Kesesuaian Kompetensi Dasar dengan Bahan Ajar Bahasa Arab MTs Kelas IX Karya Yushi M. Mahmudah
Authors: Mufti Ali , Mudrofin Mudrofin
Published: March 2022

The Indonesian Ministry of Religion has published Arabic textbooks for ninth grade to assist the implementation of the revision of the Core and Basic Competencies. The purpose of this research is to evaluate the compatibility of Arabic teaching materials with the Basic Competencies outlined in KMA No. 183 of 2019. The study employs a library research design with the data collected using documentation. The sample was selected using purposive sampling techniques, namely the content examination and assessment. Content analysis was performed to analyze the data. The results showed that some contents of the textbook did not comply with the requirements of the basic competence. Several readings and conversational texts did not instance of grammatical structures in use. The textbook did not contain practice questions for mahrah istima'. Also, only 13 (out of 34) questions in the mahārah istimā' segment pertain to higher-order thinking skills (HOTS), while the majority of the questions in mahārah kalām and kitābah pertains to the basic competence of 2013 Curriculum.
Metode Komunikatif dengan Role Play Berbasis Gender dalam Pembelajaran Kalām
Authors: Musyrifa Furaida Ayu , Luthfi Khabibi Muhammad
Published: March 2022

The purpose of this paper is to examine the relationship between communicative methods and role play in a philosophical-methodological manner, and to apply role play in gender-based kalām learning. This is motivated by the uncertainty of the position and the theoretical foundation of the communicative method and role play in the structure of the Arabic learning methodology. In addition, so far the study of methodology has been limited to structural-procedural, has not touched the meaning-contextual aspect so that it cannot include certain values, such as gender justice, even though behind Arabic there is a patriarchal culture of the Arab nation which should be minimized. With a philosophical-methodological approach based on library data and discourse analysis, it is found that role playing is a technique of the communicative method. When role play is applied in gender-based kalām learning, the concept of elements at the philosophical-theoretical and implementative-technical levels of the communicative method must be reconstructed with an anthropolinguistic approach using critical discourse analysis from poststructural equipped with additional components, such as text, themes, role functions, how to form groups, convey educators, and linguistics, which are based on the discourse of gender justice.
Role of Physiotherapyin Respiratory Rehabilitation and Managing COVID-19 Patients in All Stages of the Disease
Authors:   Mulungushi University, Miyanda Petty
Published: March 2022

Background:Physiotherapists play a crucial role in the management of corona virus disease (COVID-19) patients in all stages for better health (physical and social) outcomes. This document outlines and summarizes the updated official guidelines on roles and recommendations for physiotherapists in the management of all COVID-19 stages in acute hospital settings issued by World Confederation for physical therapy, World Health Organization and Associations of Physical Therapy in various countries. Methods:An introductory literature search was conducted by using keywords including “COVID-19”, “respiratory rehabilitation”, “physical therapy”, and others in the database of the Associations of Physical Therapy. Results:Using coronavirus disease-2019 rehabilitation-related articles data was summarized on various guidelines and recommendations involving respiratory rehabilitation and general physiotherapy evaluation; treatment; indications; contraindications; and termination indicators for patients in different stages (acute, stable and recovery) of (COVID-19)Conclusion:Respiratory and physical therapy (PT) for patients with coronavirus disease should be conducted according to the stage of the disease and condition of the patient. This article is intended for use by physiotherapy personnel and other relevant health personnel in the acute care setting caring for patients with confirmed COVID-19 highlighting their roles regarding patient assessment, management strategies, indications, contraindications and termination of physical therapy.
The Effects of Curcumin Supplementation on Metabolic Biomarkers and Body Mass
Index in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and
Meta-analysis of Randomized Controlled Trials
Authors: Khalili Leila , Nammi Srinivas
Published: March 2022

Background and Aims:

Curcumin is one of the most commonly used indigenous molecules endowed
with various shielding functionalities that protect the liver. In the present research, we aimed to investigate
the effects of curcumin on metabolic factors and body mass index (BMI) in patients with non-alcoholic fatty
liver disease (NAFLD) using a meta-analysis of randomized, controlled trials.

Methods::

Online databases PubMed, Embase, Web of Science, and Science Direct were searched until April
2021 to identify eligible articles. Fourteen trials were included.

Results:

The results showed that curcumin consumption can significantly reduce AST (-0.35, (-0.57 to
-0.14)), total cholesterol (-0.81, (-1.34 to -0.27)), TG (-0.49, (-0.71 to -0.27)), and FBS (-0.28, (-0.46 to -0.09))
in patients with NAFLD. However, the improvements in ALT (-0.29, (-0.58 to 0.00)), LDL (-0.48, (-0.97 to
0.01)), HDL (0.03, (-0.38 to 0.44)), and BMI (-0.13, (-0.29 to 0.02)) were not statistically significant. Furthermore,
the findings revealed that the optimal dose and duration of curcumin consumption for patients with
NAFLD is <500 mg/d for less than 10 weeks.

Conclusions:

The present study suggests that consuming curcumin can improve liver enzymes, lipid profile,
FBS, and BMI in patients with NAFLD. Moreover, curcumin supplementation may provide beneficial effects
on metabolic biomarkers and body weight if used at the appropriate dose and duration. Further RCTs are
required to confirm our findings.
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review
Authors: Hassanshahi Gholamhossein , Karimabad Mojgan Noroozi , Mohamadi Maryam , Torabizadeh Seyedeh Atekeh
Published: March 2022

Leukemia or blood cancer was initially discovered in 1845 and this malignancy was reported in patients who had an amplified number of blood cells, in particular, white blood cells (WBC), due to this disease. The event of leukemia was further identified as a malignant hematopoietic disorder due to both uncontrolled and unlimited proliferation in combination with lack of differentiation of the leukemic stem cells.Furethermore, 75 to 80% of the global population use herbal remedies as primary therapy, mainly because of their better efficiency and satisfaction, which elevate the human body symmetry with the minimum unwanted adverse effects. For the control of cancer, plant products, and fruits have been considered promising tools and are being consumed for centuries. Several plant extracts are also being used for the therapy and prevention of different types of known cancers. Indole-3-carbinol (I3C) is a natural material obtained from Brassica diversity of vegetables and has been reported to serve as a promising cancer preventative agent. In the present review, theauthors mainly tried to focus and emphasize I3C applications in the leukemia treatment.
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art
Authors: Losurdo Giuseppe , D’Abramo Fulvio Salvatore , Piazzolla Mariapaola , Rima Raffaella , Continisio Antonio , Pricci Maria , Ierardi Enzo , Di Leo Alfredo
Published: March 2022

Helicobacter pylori (H. pylori) is a Gram negative spiraliform bacterium that colonizes the human stomach. It is the most common cause of chronic gastritis, peptic ulcer, and gastric carcinoma. The eradication therapy is based on the combination of a proton pump inhibitor and several antibiotics such as amoxicillin, metronidazole, clarithromycin, levofloxacin or tetracycline. The most commonly used regimens for eradication in the first line are triple, sequential and concomitant therapy, despite the last European Guidelines suggesting a quadruple therapy already at the first attempt in areas with high resistance rates. However, the rise in antibiotic resistance is the main reason for a marked increase in first-line therapy failure. Clarithromycin resistancea, is especially acknowledged as the most important event resulting in failure. Up to 20% of patients are intended not to eradicate, therefore they will need a second line therapy. Currently, the most used rescue regimens are levofloxacin-based triple therapy and bismuth-containing quadruple therapy, despite guidelines suggesting to use a combination of antibiotics that have not been included in previous treatments. Nitazoxanide is a novel antibiotic with promising results. Additionally, an interesting field worth of investigation is the antibiotic susceptibility based approach, which could help choose antibiotics with confirmed effectiveness in vitro. Analysis of antibiotic resistance may be performed by both bacterial culture and molecular biology techniques, able to detect point mutations conferring resistance. This is a particularly interesting approach, since it may personalize the therapy, thus optimizing the regimen and maximizing the probability of success.
Complex Processes Underlying the Dynamic Changes of D-serine Levels in
AD Brains
Authors: Ni Xiance , Mori Hisashi
Published: March 2022

Background:

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by
extracellular β-amyloid (Aβ) plaques and cognitive impairments. D-Serine, produced by the enzyme
serine racemase (SR) in the brain, functions as an endogenous co-agonist at the glycine-binding site
of N-methyl-D-aspartate receptor (NMDAR), has been implicated in the pathophysiological progression
of AD.

Purpose:

Evidence regarding the understanding of the role and dynamic modulation of D-serine during
AD progression remains controversial. This literature review aims to offer novel research directions
for studying the functions and metabolisms of D-serine in AD brains.

Method:

We searched PubMed, using D-serine/SR and AD as keywords. Studies related to NMDAR
dysfunction, neuronal excitotoxicity, D-serine dynamic changes and inflammatory response were included.

Results:

This review primarily discusses: (i) Aβ oligomers’ role in NMDAR dysregulation, and the
subsequent synaptic dysfunction and neuronal damage in AD, (ii) D-serine’s role in NMDAR-elicited
excitotoxicity, and (iii) the involvement of D-serine and SR in AD-related inflammatory pathological
progression.

Conclusion:

We also presented supposed metabolism and dynamic changes of D-serine during AD
progression and hypothesized that: (i) the possible modulation of D-serine levels or SR expression as
an effective method of alleviating neurotoxicity during AD pathophysiological progression, and (ii)
the dynamic changes of D-serine levels in AD brains possibly resulting from complex processes.
Novel Derivatives Based on Zerumbone Scaffold as Potential Anticancer
Inhibitors
Authors: Hieu Luu Xuan , Ha Tran Thi Hong , Chi Hoang Kim , Vu Tran Khac , Chung Pham Van , Hung Truong Ngoc , Chinh Luu Van
Published: March 2022

A two-step procedure was applied to couple zerumbone, a natural sesquiterpene, with thiols
8a-k to obtain a small library of ten novel zerumbone derivatives 9a-k with full-length library data of
spectra including 1H-, 13C-NMR, and HRMS. The tautomerization of 9a, 9b, and 9c was revealed in
DMSO and discussed in the case of 9c. The series of 9a-k together with zerumbone 1 was evaluated
for their in vitro cytotoxic activity using three human cancer cell lines, HepG2, A549 and HeLa. The
results revealed that all zerumbone derivatives had cytotoxic activity against HepG2, A549, and HeLa
cells that was 4-20 times stronger than zerumbone.
Multiple Leiomyomas in a Patient with Benign Metastasizing Leiomyoma:
A Case Report
Authors: Liu Shuangjiao , Zhou Wenming , Fu Weidong
Published: March 2022

Introduction:

Benign metastasizing leiomyoma (BML) is a rare disease and mostly affects
females with a history of uterine leiomyoma, and particularly the presence of multiple leiomyomas in
BML patients is extremely rare.

Case Presentation:

This paper reported the clinical and imaging data of a BML patient with multiple
leiomyomas involving bilateral pulmonary, mediastinum, pericardium, spine, peritoneum, and left thigh.
Multiple BML lesions exhibited consistent imaging examinations, significantly improving the delayed
phase enhancement. After multi-stage targeted therapy for multiple systemic metastases and the development
of drug resistance, the patient was treated with hysterectomy and bilateral adnexectomy along
with letrozole-based endocrine therapy. BML lesions, both pulmonary and mediastinum, became significantly
smaller than before.

Conclusion:

This paper aims to analyze the imaging and clinical features of multiple leiomyomas in this
BML case, thus strengthening the understanding of the rare type of leiomyoma for effective preoperative
diagnosis and clinical treatment. Furthermore, it is noteworthy that gynecologists should avoid the
manifestation of BML when performing uterine fibroids surgery.
α-Glucosidase and α-Amylase Inhibition Study andIn SilicoAnalysis ofMimosa pudicaL. of Nepalese Origin
Authors: Shrestha Dipesh , Pokhrel Tamlal , Dhakal Kamal , Pandey Anisha , Sharma Prabha , Sapkota Sima , Adhikari Achyut
Published: March 2022

Background:

Diabetes has become a considerably more frequent condition and has increased alarmingly in recent years, possibly due to the adoption of modern lifestyle and food habits. The two prominent features of diabetes mellitus are high blood glucose and insulin deficiency, leading to severe consequences. Developing next-generation anti-diabetic medicines with fewer side effects has been a major focus in this situation.

Objective:

This research aimed to investigate the total phenolic and flavonoid content, antioxidant, antibacterial, α-amylase, and α-glucosidase inhibition activity, as well as in silico analysis of Mimosa pudica L.

Methods:

The inhibitory activity against α-amylase and α-glucosidase was performed using CNPG3 and PNPG, respectively. Antioxidant activity was estimated using DPPH free radical scavenging assay. The well diffusion method was used for the antibacterial. Using folin- ciocalteu’s reagent, the total phenolic content was determined. The total flavonoid content was determined using the aluminium trichloride method. In addition, molecular docking was performed using autodock vina.

Results:

Inhibition of α-glucosidase (IC50 = 1.059±0.14μg/mL) was found to be more significant than α-amylase (IC50 = 164.9±0.95μg/mL). The plant was also found to have antioxidant activity (IC50 = 8.207 ±0.23μg/mL), as well as antibacterial activity against Staphylococcus aureus (ZOI = 13mm) and Bacillus subtilis (ZOI = 10mm). Similarly, the total phenolic and flavonoid content was found to be 177.93±1.8 mg GAE/g, and 19.747±6.11 mg QE/g, respectively. In addition, compounds (stigmasterol, quercetin, and avicularin) isolated from M. pudica showed perfect binding to the enzyme’s active site.

Conclusion:

Mimosa pudica of Nepalese origin possess potent inhibition against digestive enzymes. Therefore, M. pudica can be used as an alternative therapeutic source to combat the global threat of diabetes.
The Toxic Effects of Endocrine Disrupting Chemicals (EDCs) on Gut
Microbiota: Bisphenol A (BPA) A Review
Authors: Charitos Ioannis Alexandros , Topi Skender , Gagliano-Candela Roberto , De Nitto Emanuele , Polimeno Lorenzo , Montagnani Monica , Santacroce Luigi
Published: March 2022

Background:

Bisphenol A (BPA), an important industrial material widely applied in daily products, is considered an endocrine-disrupting chemical that may adversely affect humans. Grow-ing evidence has shown that intestinal bacterial alterations caused by BPA exposure play an im-portant role in several local and systemic diseases.

Aim:

finding evidence that BPA-induced alterations in gut microbiota composition and activity may perturb its role on human health.

Results:

Evidence from several experimental settings shows that both low and high doses of BPA in-terfere with the hormonal, homeostatic, and reproductive systems in animals and humans. Moreover, it has recently been classified as an environmental obesogenic, with metabolic-disrupting effects on lipid metabolism and pancreatic b-cell functions. Several evidence characterizes PBA as an envi-ronmental contributor to type II diabetes, metabolic syndromes, and obesity. However, the highest estimates of the exposure derived from foods alone or in combination with other sources are 3 to 5 times below the new tolerable daily intake (TDI) value, today reduced by the European Food Safety Authority (EFSA) experts from 50 micrograms per kilogramme of bodyweight per day (μg/kg bw/day) to 4 μg/kg bw/day.

Conclusions:

Considering estimates for the total amount of BPA that can be ingested daily over a lifetime, many International Health Authorities conclude that dietary exposure of adult humans to BPA does not represent a risk to consumers' health, declaring its safety due to very-low established levels in food and water and any appreciable health risk.
A Discursive Review of Recent Development and Patents on Glycerosomes
Authors: Singh Ragini , Zeeshan Fatima , Srivastava Dipti , Awasthi Himani
Published: March 2022

Background:

To achieve a target-based drug delivery with minimal side effects, novel drug
delivery systems are being continuously explored. Vesicular systems are one such system that can
ameliorate the bioavailability of the encapsulated drug by delivering the drug at the targeted site and
can minimize the side effect.

Objective:

The objective of this review is to provide a vivid description of glycerosomes and their applications.
Glycerosomes are sphere-shaped versatile vesicles consisting of one or more phospholipid
bilayers similar to liposomes but contain a high concentration of glycerol, which modifies the liposome
bilayer fluidity. Glycerosomes can encapsulate both hydrophobic and hydrophilic drugs, which makes
them the promising vehicle in the field of drug delivery.

Conclusion:

Most of the glycerosome formulations prepared were targeted for topical delivery and in
particular, a cutaneous route where they have shown promising results. These vesicles are
biocompatible and due to the high glycerol concentration, they have improved spreadability and
penetrability. It is therefore imperative to explore the other topical routes such as ocular, vaginal, nasal,
and rectal for delivery of drugs.
SOCIAL SUPPORT IN PREGNANCY AND PARTURITION WITH MENTAL DISORDER
Authors:   S2 Kebidanan Medical Faculty University of Brawijaya, Mulyadi Jesica , Putri Winarni ,   Psychiatry Department RSUD Dr. Saiful Anwar Malang
Published: March 2022

Pregnant and childbirth are two periods in woman’s cycle life and had risk of occurrence mental disorders. Good social support is one way to minimize it. This review will explain about mental disorders and effect social support for pregnant women and childbirth with mental disorders. This article will discuss a literature review. PubMed, Medline, PsycINFO, and Web of Science, were searched including research studies published in English using the referencing period between 2000 and January 2021. Pregnancy and childbirth are the time of positive expectation and times for psychological and physiological challenges. Social support is important to intervention about common mental disorders. Social support comes from family, partner relationships, friends, etc. Social support can reduces stress in women's pregnancy and childbirth and make them enjoy and happy with their periods. Keywords: mental disorder, social support, pregnancy, childbirth.
PUBLIC RESPONSE TO CELEBRITY SUICIDES NEWS DUE TO MENTAL HEALTH ISSUES
Authors:   Medical Student of Medical Faculty University of Brawijaya, Malang, Titania Anisa
Published: March 2022

Around 800,000 people die by suicide in a year, or one per 40 seconds. Despite the fact that suicide is a complex phenomenon impacted by personal qualities as well as numerous socioenvironmental factors, it is considered as a avoidable public health problem, and public health methods to suicide prevention are fast gaining traction. Because of its vast impact, media might be considered to have a "dual-edged" polarity when it comes to mental health. It has the potential to increase mental health awareness, education, and development of treatment and service, but it also has the potential to undermine awareness, disseminate misinformation, and stigmatize mental health. This article is made by reviewing and evaluating several literatures that discusses media coverage amd public response through social media regarding the suicide of a number of celebrities and their relationship to people's mental health. The literature used is limited to articles published between 2017 – 2021. Prior research on the public's perceptions of celebrity suicide has primarily concentrated on the negative consequences, sometimes recognized as "copycat suicide" in other words "Werther effect" The positive consequences occurred when there was media coverage of a celebrity who committed suicide primarily due to mental health issue in the preceding month, the number of persons who consulted a psychiatrist increased. Increasing 'mental health awareness' on depression and suicide may help people cope with the impact of celebrity suicide news while also making it easier to get help. Inadequate mental health knowledge about depression therapy and suicide prevention may raise the likelihood of negative psychological consequences and lower the desire to seek help among those who are disturbed by such news. Keywords: celebrity, suicide, response.
THE ADVANTAGES OF NON-INVASIVE BRAIN STIMULATION FOR PATIENTS WITH MAJOR DEPRESSIVE DISORDER (MDD)
Authors:   Medical Student of Medical Faculty University of Brawijaya, Malang, Nabila Reza
Published: March 2022

Depression, reduced interest, cognitive impairment, and symptoms of vegetative growth such as sleep problem and low appetite are all signs of major depressive disorder (MDD). Depression is the fifth biggest cause of disability in Indonesia, with a prevalence of 6.1 percent. The treatment choices for major depressive disorder are psychotherapy and medication, both of which are successful in treating major depressive disorder. Despite this, doctors are confronted with clinical circumstances that are resistant to therapy or do not respond to it. For refractory individuals who have not responded to a variety of augmentation procedures or a combination of therapies, brain stimulation that is not invasive such as repeated transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) is an option. Researchers employed the literature review approach to compile the results of numerous publications that cover major depression and brain stimulation that is not invasive in depressed patients for this study. The illness effects and limits of current pharmacological and psychological methods highlight the necessity for non-invasive brain stimulation as an alternate therapy approach. Repeated TMS may aid with depressive symptoms and cognitive tasks linked to the etiology of depression. Regardless of whether rTMS and antidepressants have similar effects, combining the two is more effective than using rTMS alone. tDCS, in combination to rTMS, might be used to treat severe depressive disorder. In individuals who are hesitant to take drugs or who are unable to handle antidepressants, tDCS may be a viable option. In non-drug resistant major depression, tDCS is likely to be successful, while in drug-resistant major depression, it is likely to be unsuccessful. Keywords: depression, transcranial magnetic stimulation, direct current
HOW TO COPE WITH BABY BLUES: A CASE REPORT
Authors:   S2 Kebidanan Medical Faculty University of Brawijaya, Putri Herdian , Putri Frilya ,   Psychiatry Department Medical Faculty University of Brawijaya
Published: March 2022

During parturition phase, usually mother cannot get through psychological adaptations well, it can cause something that you might not accept-postpartum mental disorders called baby blues. There are 30-75% of women after childbirth who experience the baby blues. Many factors affect baby blues. The symptoms that begin within a few days of delivery include mood lability, irritability, tearfulness, generalized anxiety, sleep, and appetite disturbance. The author reported a case of women with baby blues. The instrument uses Edinburgh Postnatal Depression Scale (EPDS) for screening. EPDS test on the patient showed a score of 13. The patient gets treatment with classical music therapy, a support system, and continued breastfeeding. After treatment, the patient can control her emotions, sleep well, and already breastfeed the baby. The husband also takes a role in caring for their baby. EPDS test on the patient showed a score of 8. Early detection and appropriate treatment from a midwife can decrease baby blues symptoms. Keywords: post-partum mental disorder, baby blues, EPDS.
UNIPOLAR DEPRESSION TO BIPOLAR DISORDER CONVERSION
Authors:   Medical Student of Medical Faculty University of Brawijaya, Malang, Wardhani Dyah
Published: March 2022

Bipolar disorder cases have increased compared to a decade ago. It is thought that this increase is the result of a high number of bipolar patients who were not recognized early on because bipolar and unipolar depression is difficult to distinguish from one another. In addition, this problem also gave rise to the hypothesis that unipolar depression could develop into bipolar disorder. Therefore, the diagnosis conversion of unipolar depresion into bipolar disorder and its predictor needs to be studied further. Literature review by using several literatures between 2011-2021 that discuss about unipolar depresion, bipolar disorder, diagnosis conversion, and factors that influence the conversion of unipolar depression diagnosis into bipolar disorder. Diagnosis of unipolar depression can turn into bipolar disorder. This may be due to failure to differentiate unipolar and bipolar depressive episodes, strict diagnostic criteria, failure to recognize history of hypomania/mania, or due to the genuine progression of the disorders. This problem leads to the provision of inappropriate therapy for patients that trigger disease progression and worsen the prognosis. One of the anticipations that can be done is to explore the presence of conversion predictor factor. It includes the age of onset <25 years, bipolar family history, patient’s course of depression (high recurrence, short duration, moderate to severe depression, hypersomnia, psychomotor retardation, psychosis symptoms, postpartum depression), resistance to antidepressants, antidepressant-induced hypomania/mania, and the presence of subthreshold mania. If these factors are found, the patient should be closely monitored and therapy adjustment may be required. Keywords: bipolar disorder, conversion, predictor, unipolar depression.
BEHAVIORAL THERAPY TO REDUCE EMESIS IN PATIENT WITH PSYCHOGENIC VOMITING
Authors:   Medical Student of Medical Faculty University of Brawijaya, Malang, Hakim Arif
Published: March 2022

Psychogenic vomiting or “functional vomiting” is vomiting without any obvious organic pathology, resulting from psychological mechanisms. It is can occurs cause a result of an emotional disturbance or psychic disturbance without organic pathology. For the psychogenic vomiting treatment, there are previous treatment using pharmacotherapy, behavioral therapy, cognitive therapy, and supportive psychotherapy. Behavior therapy aim to changing the behavior in daily activities to reduce dysfunction and improve quality of life. Cognitive therapy aims to change psychological significance of people’s beliefs about themselve, their personal world, and the future. Author used the literature review method by collecting several literatures that discuss about psychogenic vomiting, cognitive behavioral therapy, training behavioral therapy, and supportive therapy for psychogenic vomiting. The treatment should be directed to relieving intensity of vomiting episodes and improving the patient’s health related to quality of life. The guideline of treatment of psychigenic vomiting remain unclear. Based on the literature, many various methods are used to treat psychogenic vomiting. Behavior therapy and cognitive therapy can be choosen to treat vomiting based on the underlying disease. All of the literature on psychogenic vomiting supports the use of a comprehensive, multi-disciplinary approach including pharmacological and psychotherapeutic treatment. Keywords: psychogenic vomiting, behavioral therapy, cognitive therapy.
Examining Anxiety Treatment Information Needs: Web-Based Survey Study
Authors: Bernstein Matthew T , Reynolds Kristin A , Jakobson Lorna S , Stoesz Brenda M , Alcolado Gillian M , Furer Patricia
Published: March 2022

Background

Several treatments for anxiety are available, which can make treatment decisions difficult. Resources are often produced with limited knowledge of what information is of interest to consumers. This is a problem because there is limited understanding of what people want to know when considering help for anxiety.

Objective

This study aimed to examine the information needs and preferences concerning treatment options for anxiety by assessing the following: what information people consider to be important when they are considering treatment options for anxiety, what information people have received on psychological and medication treatment in the past, how they received this information in the past, and whether there are any differences in information needs between specific samples and demographic groups.

Methods

Using a web-based survey, we recruited participants from a peer-support association website (n=288) and clinic samples (psychology, n=113; psychiatry, n=64).

Results

Participants in all samples wanted information on a broad range of topics pertaining to anxiety treatment. However, they reported that they did not receive the desired amount of information. Participants in the clinic samples rated the importance of information topics higher than did those in the self-help sample. When considering the anxiety treatment information received in the past, most respondents indicated receiving information from informational websites, family doctors, and mental health practitioners. In terms of what respondents want to learn about, high ratings of importance were given to topics concerning treatment effectiveness, how it works, advantages and disadvantages, what happens when it stops, and common side effects.

Conclusions

It is challenging for individuals to obtain anxiety-related information on the range of topics they desire through currently available information sources. It is also difficult to provide comprehensive information during typical clinical visits. Providing evidence-based information on the web and in a brochure format may help consumers make informed choices and support the advice provided by health professionals.
Acceptability and Feasibility of a Return-to-Work Intervention for Posttreatment Breast Cancer Survivors: Protocol for a Co-design and Development Study
Authors: Bilodeau Karine , Gouin Marie-Michelle , Lecours Alexandra , Lederer Valérie , Durand Marie-José , Kilpatrick Kelley , Lepage David , Ladouceur-Deslauriers Lauriane , Dorta Tomas
Published: March 2022

Background

The mortality rate from breast cancer has been declining for many years, and the population size of working-age survivors is steadily increasing. However, the recurrent side effects of cancer and its treatment can result in multiple disabilities and disruptions to day-to-day life, including work disruptions. Despite the existing knowledge of best practices regarding return to work (RTW) for breast cancer survivors, only a few interdisciplinary interventions have been developed to address the individualized needs and multiple challenges of breast cancer survivors, health care professionals, and employer and insurer representatives. Thus, it seems appropriate to develop RTW interventions collaboratively by using a co-design approach with these specific stakeholders.

Objective

This paper presents a protocol for developing and testing an innovative, interdisciplinary pilot intervention based on a co-design approach to better support RTW and job retention after breast cancer treatment.

Methods

First, a participatory research approach will be used to develop the intervention in a co-design workshop with 12 to 20 participants, including people affected by cancer, employer and insurer representatives, and health care professionals. Next, a pilot intervention will be tested in a primary care setting with 6 to 8 women affected by breast cancer. The acceptability and feasibility of the pilot intervention will be pretested through semistructured interviews with participants, health care professionals, and involved patient partners. The transcribed data will undergo an iterative content analysis.

Results

The first phase of the project—the co-design workshop—was completed in June 2021. The pilot test of the intervention will begin in spring 2022. The results from the test will be available in late 2022.

Conclusions

The project will offer novel data regarding the use of the co-design approach for the development of innovative, co-designed interventions. In addition, it will be possible to document the acceptability and feasibility of the pilot intervention with a primary care team. Depending on the results obtained, the intervention could be implemented on a larger scale.

International Registered Report Identifier (IRRID)

DERR1-10.2196/37009
Peer Review of “Measuring Integrated Novel Dimensions in Neurodevelopmental and Stress-Related Mental Disorders (MIND-SET): Protocol for a Cross-sectional Comorbidity Study From a Research Domain Criteria Perspective” (Preprint)
Authors: Birk Max V
Published: March 2022

UNSTRUCTURED

This is a peer review report related to MS ID#31269.
Experiences Among Patients With Cystic Fibrosis in the MucoExocet Study of Using Connected Devices for the Management of Pulmonary Exacerbations: Grounded Theory Qualitative Research (Preprint)
Authors: Morsa Maxime , Perrin Amélie , David Valérie , Rault Gilles , Le Roux Enora , Alberti Corinne , Gagnayre Rémi , Pougheon Bertrand Dominique
Published: March 2022

BACKGROUND

Early detection of pulmonary exacerbations (PEx) in patients with cystic fibrosis is important to quickly trigger treatment and reduce respiratory damage. An intervention was designed in the frame of the MucoExocet research study providing patients with cystic fibrosis with connected devices and educating them to detect and react to their early signs of PEx.

OBJECTIVE

This study aims to identify the contributions and conditions of home monitoring in relation to their care teams from the users’ point of view to detect PEx early and treat it. This study focused on the patients’ experiences as the first and main users of home monitoring.

METHODS

A qualitative study was conducted to explore patients’ and professionals’ experiences with the intervention. We interviewed patients who completed the 2-year study using semistructured guides and conducted focus groups with the care teams. All the interviews were recorded and transcribed verbatim. Their educational material was collected. A grounded analysis was conducted by 2 researchers.

RESULTS

A total of 20 patients completed the study. Three main categories emerged from the patients’ verbatim transcripts and were also found in those of the professionals: (1) task technology fit, reflecting reliability, ease of use, accuracy of data, and support of the technology; (2) patient empowerment through technology, grouping patients’ learnings, validation of their perception of exacerbation, assessment of treatment efficacy, awareness of healthy behaviors, and ability to react to PEx signs in relation to their care team; (3) use, reflecting a continuous or intermittent use, the perceived usefulness balanced with cumbersome measurements, routinization and personalization of the measurement process, and the way data are shared with the care team. Furthermore, 3 relationships were highlighted between the categories that reflect the necessary conditions for patient empowerment through the use of technology.

CONCLUSIONS

We discuss a theorization of the process of patient empowerment through the use of connected devices and call for further research to verify or amend it in the context of other technologies, illnesses, and care organizations.

CLINICALTRIAL

ClinicalTrials.gov NCT03304028; https://clinicaltrials.gov/ct2/show/results/NCT03304028
Early detection of new pandemic waves: A surveillance alternative to the 14-day cumulative incidence index. (Preprint)
Authors: Cildoz Marta , Gaston Martin , Frias Laura , García de Vicuña Daniel , Azcarate Cristina , Mallor Fermín
Published: March 2022

BACKGROUND

The current COVID-19 pandemic highlights the pressing need for constant surveillance, updating of the response plan in post-peak periods and readiness for the possibility of new waves of the pandemic. The system for monitoring and controlling the spread of the pandemic should signal an alert in the event of change in the infection process.

OBJECTIVE

The 14-day notification rate of reported COVID-19 cases per 100,000 population is the main indicator used for continued monitoring of the evolution of the pandemic. However, this value may neither accurately represent the current state of virus spread among the population nor provide a good approximation of the rate at which positivity changes. Thus, we propose a new way to detect changes in the virus spread.

METHODS

We introduce a new index, the weighted cumulative incidence index, based on the daily new cases count, which is more able to reflect both the current state of virus transmission and the current rate of change. We propose to model infection spread at two levels, inside and outside the home, to explain the overdispersion observed in the data. The seasonal component on real data, due to the detection system carried out by the public health services, is incorporated into the statistical analysis. For the first time in this context, we also provide a control chart to monitor the index, in order to detect significant variations in the virus transmission process.

RESULTS

Both the new index and the control chart have been implemented in a computational aid tool developed in Python, which is used daily by the Government of Navarra (Spain) in the virus propagation surveillance during post-peak periods. Automated monitoring generates a daily report showing the areas whose control charts issue an alert.

CONCLUSIONS

After the application of the proposed index to real data, the results confirm that our study provides a new index which is quicker at detecting significant changes in the virus spread than the commonly used 14-day cumulative index. This quickness allows to plan more efficiently the subsequent decisions in pandemic surveillance.
Achievements, Experience and Implications of China’s Poverty Governance
Authors: Su Xiangjun
Published: March 2022

Poverty is one of the challenges faced by the world, and poverty alleviation is the shared responsibility for humanity. As an active advocate and strong promoter of global poverty alleviation, China has taken the lead in completely eradicating absolute poverty, contributing China model of global poverty governance. This paper summarizes the great historic achievements and landmark significance of China’s poverty alleviation, and analyzes the successful experience of China’s poverty governance, pointing out that the poverty reduction path with Chinese characteristics is a new path for human anti-poverty cause, and the experience and wisdom of China’s poverty governance is the common wealth for mankind, of which attaching great importance to poverty alleviation, adhering to the development-oriented poverty alleviation approach, implementing targeted poverty alleviation strategy and strengthening all-round effective supervision are not only the magic weapons for China’s success in poverty reduction, but also an important reference for the global poverty governance.
UN LLAMADO NEOTROPICAL: REPOSITORIOS ACÚSTICOS DE LA HERPETOLOGÍA LATINOAMERICANA
Authors: Mendoza-Henao Angela , Ordoñez-Flores Samantha , Dena Simone , Toledo Luis Felipe , Guayasamín Juan M. , Franco Mena Daniela , Acevedo-Charry Orlando
Published: March 2022

En las últimas décadas, el desarrollo de nuevas técnicas de muestreo nos ha permitido recolectar con mayor facilidad novedosas muestras que enriquecen el conocimiento de los especímenes que estudiamos. En este sentido, las muestras audiovisuales, sobre todo las grabaciones de señales acústicas, se han convertido en parte esencial de la investigación herpetológica. El correcto almacenamiento de estos especímenes es clave para fortalecer la investigación científica. Sin embargo, la gran mayoría de repositorios audiovisuales de acceso público se encuentran en países del Norte Global, lo cual restringe la labor científica en países latinos. El uso de repositorios locales o regionales abre la posibilidad de almacenar la diversidad de muestras científicas generadas en la región, haciéndolas fácilmente accesibles a los investigadores regionales y a la divulgación de la ciencia local. Esta carta es un llamado urgente a la comunidad herpetológica en Latinoamérica para que se tomen tres acciones principales como comunidad para aumentar la accesibilidad, reproducibilidad y crecimiento de la investigación bioacústica de anfibios neotropicales:  1) los investigadores deben depositar las grabaciones usadas en investigaciones publicadas en repositorios acústicos nacionales o regionales, 2)  las editoriales y revisores de documentos deben exigir a los autores los números de depósito de todos los archivos utilizados en cualquier investigación acústica y la correcta referenciación de las colecciones usadas para poder aceptar los manuscritos y, 3) las directivas de las instituciones regionales con repositorios deben garantizar el fortalecimiento y mantenimiento de los repositorios acústicos institucionales por parte de las directivas de instituciones regionales.
Role and Benefits of Sports Psychology for the Improvement of Performance of Sports Persons
Authors: Mehta Dr. Vikas
Published: March 2022

Abstract: The acceptance of sport psychology, both as an academic discipline as well as an applied process, has grown considerably over the past 2 years. Sports performance is determined by a combination of physiological factors, technical skill, tactical insight and state of mind. Every top sportsperson knows that their best performances come from their mind as much as their body. Not many to the world of competitive athletics would argue with the significance of being psychologically ready just before an athletic competition along with the want to help keep this specific mindset during a competitive competition. As a result, the goal of this report is actually providing the viewer with a basic framework depicting how mental skills education translates into enhanced competition efficiency. This particular framework is meant to help bridge the common "understanding gap" that's presently being described by a lot of coaches and athletes, while simultaneously helping sport psychology practitioners market their valuable services to specific athletes & teams. The paper concluded by stating sport psychology must be used as scientific instruction ways for athletes to be able to improve sports performance. Keyword: sports psychology, athlete, performance
Melonoma Identification By Using 3D Convolutional Neural Network
Authors: . Nkumaran , Kumar Chimmiri Venkata Manoj , Kumar Pothuri Ajay
Published: March 2022

Abstract: Skin biopsy histopathological investigation is one of the essential techniques utilized for pathologists to survey the presence and weakening of melanoma in clinical. A complete and dependable neurotic examination is the consequence of accurately sectioned melanoma and its connection with harmless tissues, and in this way giving precise treatment. In this review, we applied the profound convolution network on the hyper ghastly pathology pictures to play out the division of melanoma. To utilize unearthly properties of three layered hyper otherworldly information, we proposed a 3D completely convolutional network named Hyper-net to section melanoma from hyper phantom pathology pictures. To upgrade the awareness of the model, we made a particular alteration to the misfortune work with wariness of misleading negative in conclusion. The presentation of Hyper-net outperformed the 2D model with the exactness more than 92%. The bogus negative rate diminished by almost 66% utilizing Hyper-net with the adjusted shortfall work. These discoveries showed the capacity of the Hyper-net for helping pathologists in analysis of melanoma in view of hyperspectral pathology pictures. Keywords: Microscopy,Segmentation,skin Qualification,and imag
A Concise Survey Paper on Automated Plant Irrigation System
Authors: K S Joji Mitto , Savant Dr. Preeti
Published: March 2022

Abstract: In the present day world Scarcity of meals and water mainly takes place due to the increase in population in order to keep away from this there's a need to sell the agriculture zone. Agriculture is one of India's most important industries, accounting for 18% of the country's GDP. The best yield is determined by the irrigation device utilised, which has an impact on the sector. The traditional irrigation arrangements employed in the major components do not deliver the best yield for the plants. The venture's main goal is to develop an Automated Irrigation System that may be used to supplement traditional irrigation methods. The job isn't necessarily restricted to the agriculture sector; it may also be done at our homes or businesses with lawns and plants. There are a whole lot of wastage water and other sources within the crop discipline. In order to prevent this difficulty, we're using an Arduino-based automatic plant irrigating device. This instrument measures the moisture content of the soil and provides sufficient water in accordance with the need .So while the soil is dry the pump will robotic-ally water the fields and whilst the soil is wet the pump robotic-ally stops, there by eradicate the want of manpower and preserve the time. Keywords: Arduino, Irrigation, Agriculture.
Review on Camera based Surveillance Systems
Authors: Farhat Mrs. Naziya , Nasiruddin Mohammad
Published: March 2022

Abstract: Surveillance systems that use cameras to monitor the environment are known as automated surveillance systems. Motion detection, crowd behavior, individual behavior, and interactions between persons, crowds, and their surrounding environment are all used to analyses the observed scenario. These automated systems perform a wide range of functions, including detection, interpretation, comprehension, recording, and the generation of alarms based on the analysis. By manipulating various elements of these systems, researchers have been able to improve monitoring performance while minimizing possible human failings. This study provides a thorough examination of such video surveillance systems and the components that go with them. The architectures that were employed are described, along with the most important analyses in these systems. Existing surveillance systems were compared in terms of to provide a wider picture and a more holistic understanding of the system.