bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnostic and treatment dilemma during the coronavirus disease 2019 pandemic: a primary pulmonary lymphoma presenting as a cavitary mass in a patient with coronavirus disease 2019: a case report
Authors: Wong Fatima , Doyle-McClam Megan , Pugh Spencer , Dudney Tina , McCormack Michael , Kravitz Jared
Published: January 2023

Background

A radiological finding of a cavitary pulmonary lesion in a patient acutely infected with severe acute respiratory syndrome coronavirus-2 early during the coronavirus disease 2019 pandemic created a diagnostic and treatment dilemma, as invasive procedures with bronchoscopy and percutaneous needle lung biopsy posed an infection hazard to healthcare workers due to the associated risk of viral aerosolization. Available guidelines recommended delay of non-emergent procedures, but timely proceeding with those deemed urgent provided appropriate personal protective equipment and negative pressure isolation were available and exposure risk was not excessive. Thoughtful consideration by clinicians was required to avoid delay in diagnosis of a potential new malignancy and prevent unnecessary healthcare worker exposure to the virus. Additionally, acute severe acute respiratory syndrome coronavirus-2 infection in patients with malignancy complicated timing of oncologic treatment.

Case presentation

A 26-year-old otherwise healthy Caucasian male initially presented with an enlarging right upper lobe cavitary pulmonary lesion despite antimicrobial therapy. During his hospitalization and evaluation, the patient was found to be acutely infected with severe acute respiratory syndrome coronavirus-2 without hypoxia or viral pneumonia. Bronchoscopy was deemed too high risk for viral aerosolization and healthcare worker infection. He underwent computed-tomography-guided percutaneous needle biopsy of the lesion by interventional radiology while on mechanical ventilation after elective intubation by anesthesiology. Biopsy revealed classic Hodgkin lymphoma consistent with primary pulmonary Hodgkin lymphoma. After collaboration with oncology, his treatment with combined chemotherapy and immunotherapy was delayed for 3 weeks following diagnosis to allow for viral clearance.

Conclusion

A careful multidisciplinary strategy is required to expeditiously diagnose and treat aggressive cancers of the respiratory tract in patients acutely infected with severe acute respiratory syndrome coronavirus-2 while observing practices to prevent healthcare worker infection during the ongoing coronavirus disease 2019 pandemic.
Environmental impact on carcinogenesis under BRCA1 haploinsufficiency
Authors: Toyokuni Shinya , Kong Yingyi , Motooka Yashiro , Akatsuka Shinya
Published: January 2023

Cancer is the primary cause of human mortality in Japan since 1981. Although numerous novel therapies have been developed and applied in clinics, the number of deaths from cancer is still increasing worldwide. It is time to consider the strategy of cancer prevention more seriously. Here we propose a hypothesis that cancer can be side effects of long time-use of iron and oxygen and that carcinogenesis is an evolution-like cellular events to obtain “iron addiction with ferroptosis-resistance” where genes and environment interact each other. Among the recognized genetic risk factors for carcinogenesis, we here focus on BRCA1 tumor suppressor gene and how environmental factors, including daily life exposure and diets, may impact toward carcinogenesis under BRCA1 haploinsufficiency. Although mice models of BRCA1 mutants have not been successful for decades in generating phenotype mimicking the human counterparts, a rat model of BRCA1 mutant was recently established that reasonably mimics the human phenotype. Two distinct categories of oxidative stress, one by radiation and one by iron-catalyzed Fenton reaction, promoted carcinogenesis in Brca1 rat mutants. Furthermore, mitochondrial damage followed by alteration of iron metabolism finally resulted in ferroptosis-resistance of target cells in carcinogenesis. These suggest a possibility that cancer prevention by active pharmacological intervention may be possible for BRCA1 mutants to increase the quality of their life rather than preventive mastectomy and/or oophorectomy.
Insecticide susceptibility status of Anopheles gambiae (s.l.) in and surrounding areas of Lake Tana, northwest Ethiopia
Authors: Kendie Fasil A. , Wale Melaku , Nibret Endalkachew , Ameha Zena
Published: January 2023

Background

Vector control is the most effective malaria control and prevention measure. Among these, IRS and LLINs are the most important chemical insecticide interventions used in malaria prevention and control strategies in Ethiopia. However, the long-term effectiveness of these strategies is under threat due to the emergency and spread of insecticide resistance in the principal malaria vector. Therefore, this study was carried out, under standardized laboratory conditions to assess the killing effect of some insecticides against An. gambiae s.l.

Methods

Mosquitoes in late instar larvae and pupae stages were collected from different breeding habitats of the study sites using a soup ladle (350 ml capacity). The immature was reared to adults at optimum temperature and humidity in a field insectary using the WHO protocol. Four insecticides representing three chemical classes were used against adult mosquitoes. These were permethrin, deltamethrin, pirimiphos-methyl and bendiocarb. Susceptibility tests were carried out from September to December 2021 using the WHO standard procedures. Mortality rate, variation, interaction effect and knockdown times (KDT50 and KDT95%) were computed using descriptive statistics, multivariate analysis of variance and log-probit regression model using SPSS version 20 software.

Results

Totally, 1300 Anopheles gambiae s.l. were tested to determine the susceptibility status to the four insecticides. Among these, 90.7% of them were susceptible to insecticides, whereas the remaining 9.3% of specimens were resistant to the insecticides. The results of the analysis of variance showed that mortality significantly varied between insecticides (F = 26.06, DF = 3, P < .0001), but not between study locations (F = 1.56, DF = 3, P = 0.212). On the other hand, the mean comparison of dead mosquitoes showed some signs of interaction between bendiocarb and locations, but not other insecticides and locations.

Conclusions

This study revealed that the knockdown times and effectiveness of different insecticides varied in different study sites. Therefore, insecticide resistance information is very essential for concerned bodies to make informed and evidence-based decisions on vector control.
Patterns of Health Portal Use by Regular Portal Users Among Patients With Cancer: Results From the UWCCC Survivorship Program
Authors: Emamekhoo Hamid , Chandereng Thevaa , Sesto Mary E. , Luoh Rebecca , Bergeson Elena M. , Barbosa Carroll Cibele , Tevaarwerk Amye J.
Published: January 2023

PURPOSE

We sought to evaluate the patterns of portal usage among patients with cancer who regularly log in to the portal. These data will inform approaches to facilitate portal use among patients with cancer.

PATIENTS AND METHODS

We conducted a retrospective analysis of patient portal usage by patients with cancer at the University of Wisconsin Carbone Cancer Center. Our analysis focuses on patterns of portal use by regular users (≥ 2 portal logins/year, > 3 months) receiving ongoing oncology care between January 1, 2017, and December 31, 2019. Demographics, cancer characteristics, number of oncology visits per month, and portal usage data were extracted. Regular portal users were grouped and compared on the basis of their frequency of use. A linear mixed-effects model was used to determine if the frequency of oncology visits influenced the number of logins.

RESULTS

We identified 2076 regular portal users. The median number of portal logins/year was 72 for the entire cohort. Age and race were associated with frequency of portal logins. There was no difference in frequency of portal login on the basis of cancer type or stage. Each additional oncology office visit in a month increased the frequency of portal logins by 3.05 ± 0.11 (SE) within the same month. Messages and test result functionalities were used by 98.7% and 98.9% of the regular users, respectively. Regular users who logged in to portal more frequently used all five studied portal functionalities.

CONCLUSION

Patients with cancer who use portals regularly use it more in proximity to an oncology office visit and use multiple available portal functionalities. These findings can direct strategic planning to facilitate portal utilization among those not engaged with this tool.
Percutaneous Direct Pars Repair in Young Athletes
Authors: Jamshidi Aria M. , Soldozy Sauson , Levi Allan D.
Published: January 2023

BACKGROUND:

Lumbar pars defects are common in adolescent athletes and are often due to recurrent axial loading and traumatic stressors.

OBJECTIVE:

To present an updated case series of young athletes who underwent percutaneous direct pars repair after failure of conservative management.

METHODS:

A single-center, nonrandomized, retrospective observation study of athletes who were referred for minimally invasive direct pars repair after failure of at least 6 months of conservative management was performed. Summary demographic information, clinical features of presentation, perioperative and intraoperative radiographic imaging, and visual analog scale back pain scores were collected and analyzed.

RESULTS:

A total of 21 patients were included (mean age [± SD] 17.47 ± 3.02 years, range 14-25 years), 6 of whom were female (29%). All patients presented with bilateral pars fractures, with L5 being the most frequent level involved (n = 13). The average follow-up time was 31.52 ± 9.38 months (range 3-110 months). The visual analog scale score for back pain was significantly reduced from 7.62 ± 1.83 preoperatively to 0.28 ± 0.56 at the final postoperative examination (P < .01). Fusion was noted in 20 of the 21 patients on final follow-up (95%).

CONCLUSION:

Percutaneous direct pars repair is a safe and effective means in treating young adolescents who have failed conservative management. The advantages included minimized muscle and soft tissue dissection, reduced blood loss, and early mobilization and recovery. In young athletes who desire return to high-level physical activity, this surgical technique is of particular benefit and should be considered in this patient population.
Gamma Knife Central Lateral Thalamotomy for Chronic Neuropathic Pain: A Single-Center, Retrospective Study
Authors: Franzini Andrea , Ninatti Gaia , Rossini Zefferino , Tropeano Maria Pia , Clerici Elena , Navarria Pierina , Pessina Federico , Picozzi Piero
Published: January 2023

BACKGROUND:

Chronic neuropathic pain can be severely disabling and is difficult to treat. The medial thalamus is believed to be involved in the processing of the affective-motivational dimension of pain, and lesioning of the medial thalamus has been used as a potential treatment for neuropathic pain. Within the medial thalamus, the central lateral nucleus has been considered as a target for stereotactic lesioning.

OBJECTIVE:

To study the safety and efficacy of central lateral thalamotomy using Gamma Knife radiosurgery (GKRS) for the treatment of neuropathic pain.

METHODS:

We retrospectively reviewed all patients with neuropathic pain who underwent central lateral thalamotomy using GKRS. We report on patient outcomes, including changes in pain scores using the Numeric Pain Rating Scale and Barrow Neurological Institute pain intensity score, and adverse events.

RESULTS:

Twenty-one patients underwent central lateral thalamotomy using GKRS between 2014 and 2021. Meaningful pain reduction occurred in 12 patients (57%) after a median period of 3 months and persisted in 7 patients (33%) at the last follow-up (the median follow-up was 28 months). Rates of pain reduction at 1, 2, 3, and 5 years were 48%, 48%, 19%, and 19%, respectively. Meaningful pain reduction occurred more frequently in patients with trigeminal deafferentation pain compared with all other patients (P = .009). No patient had treatment-related adverse events.

CONCLUSION:

Central lateral thalamotomy using GKRS is remarkably safe. Pain reduction after this procedure occurs in a subset of patients and is more frequent in those with trigeminal deafferentation pain; however, pain recurs frequently over time.
Cyst-to-Mastoid Antrum Diversion as an Alternate Pathway for Management of Small Symptomatic Petrous Apex Cholesterol Granuloma Without Anteromedial Expansion Using an Extradural Middle Fossa Approach: A Technical Case Report
Authors: Yamakami Iwao , Kubota Shunsuke , Higuchi Yoshinori , Horiguchi Kentaro , Matsuda Tatsuma
Published: January 2023

BACKGROUND AND IMPORTANCE:

Cholesterol granuloma (CG) is the most common petrous apex (PA) cystic lesion. Posterolateral expansion of a PA CG (PACG) compresses the internal auditory canal (IAC), leading to vestibulocochlear (VC) and facial nerve dysfunction. Even small, symptomatic PACGs are managed surgically. The preferred strategy is not complete removal, but drainage and aeration. PACG with anteromedial expansion using an endoscopic endonasal approach provides natural drainage into the nasal sinus without risking VC and facial dysfunction. Endoscopic endonasal approach is inappropriate for small PACGs without anteromedial expansion because of potential damage to the petrous internal carotid artery. Small PACGs without anteromedial expansion are managed using extradural middle fossa (EMF) approach, which lacks a natural drainage pathway, thus necessitating an artificial drainage pathway for PACG aeration to prevent recurrence. We introduced EMF approach for CG decompression and cyst-to-mastoid antrum (MA) diversion for managing small, symptomatic PACGs without anteromedial expansion.

CLINICAL PRESENTATION:

A 48-year-old woman presented with headache, vertigo, tinnitus, and left hemifacial spasm with preserved hearing because of IAC compression caused by a small PACG without anteromedial expansion. Using the EMF approach, the CG and IAC were safely decompressed. Effective and long-standing artificial drainage for CG aeration was established by anterior petrosectomy and silicone tubing from the CG into the MA. Surgery resolved the symptoms, which have not recurred in 3 years.

CONCLUSION:

Granuloma decompression and cyst-to-MA diversion using silicone tubing using the EMF approach is a safe and effective surgical management for small, symptomatic PACG without anteromedial expansion.
Outcomes of Arterial Bypass for Posterior Circulation Atherosclerosis: A Case Series
Authors: Farooq Jeffrey , Piper Keaton , Yeung Elton , Zhang Jianjian , van Loveren Harry , Agazzi Siviero , Lau Tsz
Published: January 2023

BACKGROUND:

Extracranial-intracranial bypass is an effective treatment option for moyamoya disease and in well-selected cases of anterior circulation intracranial atherosclerotic disease; however, the effectiveness of bypass is less evident in posterior circulation atherosclerosis. Updated surgical techniques and clinical guidelines necessitate modern appraisal of arterial bypass for symptomatic patients with posterior circulation atherosclerotic disease who are refractory to medical management.

OBJECTIVE:

To evaluate the complications, graft patency, and postoperative outcomes of arterial bypass for posterior circulation intracranial atherosclerotic disease.

METHODS:

Perioperative records of consecutive bypass patients were retrospectively evaluated to determine the clinical course and surgical outcomes.

RESULTS:

Arterial bypass was performed in 8 cases with a median age of 62 years. All 8 patients underwent direct bypass with an autologous occipital artery donor vessel. Recipient vessel selection varied on a case-by-case basis, with the superior cerebellar artery used in 4 cases, the posterior inferior cerebellar artery in 3 cases, and the anterior inferior cerebellar artery in 1 case. There were no significant intraoperative or postoperative complications. Postoperatively, all 8 patients displayed clinical improvement of their preoperative symptoms, with a significant decrease of 2.5 points on the modified Rankin Scale (P < .001). Postoperative imaging confirmed full graft patency in 7 patients and partial patency in 1 patient.

CONCLUSION:

Excellent postoperative outcomes and no major complications after posterior circulation arterial bypass for intracranial atherosclerotic disease highlight the utility of this intervention for the treatment of medically refractory or symptomatic posterior circulation intracranial atherosclerotic disease. Larger studies may be valuable to validate these findings.
Endoscope-Assisted Pedicled Maxillary Artery to Middle Cerebral Artery Bypass: An Anatomic Feasibility Study
Authors: Samarage Hasitha Milan , Kim Wi Jin , Zarrin David A. , Goel Keshav , Kim Won , Bergsneider Marvin , Wang Marilene B. , Suh Jeffrey D. , Lee Jivianne T. , Colby Geoffrey P. , Johnson Jeremiah N. , Peacock Warwick J. , Wang Anthony C.
Published: January 2023

BACKGROUND:

Extracranial to intracranial bypass is used to augment and/or replace the intracranial circulation for various pathologies. The superficial temporal artery is the mainstay donor for pedicled bypasses to the anterior circulation but can be limited by its variable size, low native flow rates, and potential scalp complications. Interposition grafts such as the radial artery or greater saphenous vein are alternatives but are sometimes limited by size mismatch, length needed to reach the extracranial circulation, and loss of inherent vascular elasticity. Interposition grafts between the maxillary artery (IMA) and middle cerebral artery (MCA) address these limitations.

OBJECTIVE:

To explore the feasibility of harvesting the IMA through an endoscopic transnasal, transmaxillary approach to perform a direct IMA to MCA bypass.

METHODS:

Combined transcranial and endoscopic endonasal dissections were performed in embalmed human cadavers to harvest the IMAs for intracranial transposition and direct anastomosis to the MCA. Donor and recipient vessel calibers were measured and recorded.

RESULTS:

A total of 8 procedures were performed using the largest and distal-most branches of the IMA (the sphenopalatine branch and the descending palatine branch) as pedicled conduits to second division of middle cerebral artery (M2) recipients. The mean diameter of the IMA donors was 1.89 mm (SD ± 0.42 mm), and the mean diameter of the recipient M2 vessels was 1.90 mm (SD ± 0.46 mm).

CONCLUSION:

Endoscopic harvest of the IMA using a transnasal, transmaxillary approach is a technically feasible option offering an excellent size match to the M2 divisions of the MCA and the advantages of a relatively short, pedicled donor vessel.
The science and technology of kinematic measurements in a century of Journal of Experimental Biology
Authors: McHenry Matthew J. , Hedrick Tyson L.
Published: January 2023

Kinematic measurements have been essential to the study of comparative biomechanics and offer insight into relationships between technological development and scientific progress. Here, we review the 100 year history of kinematic measurements in Journal of Experimental Biology (JEB) through eras that used film, analog video and digital video, and approaches that have circumvented the use of image capture. This history originated with the career of Sir James Gray and has since evolved over the generations of investigators that have followed. Although some JEB studies have featured technological developments that were ahead of their time, the vast majority of research adopted equipment that was broadly available through the consumer or industrial markets. We found that across eras, an emphasis on high-speed phenomena outpaced the growth of the number of articles published by JEB and the size of datasets increased significantly. Despite these advances, the number of species studied within individual reports has not differed significantly over time. Therefore, we find that advances in technology have helped to enable a growth in the number of JEB studies that have included kinematic measurements, contributed to an emphasis on high-speed phenomena, and yielded biomechanical studies that are more data rich, but are no more comparative now than in previous decades.
Turning a page: remaining a top competitor in an evolving publication ecosystem
Authors: Somero George N.
Published: January 2023

Journal of Experimental Biology (JEB) is celebrating its first 100 years this year. My own relationship with the journal spans over six decades and encompasses a variety of roles: reader, author, Editor (1995–2000), Editorial Advisory Board member (2000 to present) and Director on the board of its publisher, The Company of Biologists (2003–2009). I was therefore delighted when the journal Editors asked me to write a Perspective to reflect on how the journal and the publishing environment in which it competes have evolved over this long period, and to peek into my crystal ball and comment on what the future might hold for the journal and the primary fields it covers: comparative–environmental–evolutionary physiology, neuroethology and biomechanics.
Maternidades en tensión y movilidad a través de Marsella (Belén Macías, 2014).
Authors: Dueñas Mohedas Sonia , Martínez Pérez Natalia
Published: January 2023

Los modelos de madre más popularizados en los medios de comunicación desde finales de los años 80 instaban a las mujeres a sacrificar no solo su carrera profesional, sino también su identidad como individuo por sus hijos mientras, de forma contradictoria, las impulsaba a ser ambiciosas y competitivas en un ámbito laboral tradicionalmente masculinizado. Este exigente modelo ha sido cuestionado desde la ficción audiovisual durante la última década, sobre todo, a través de propuestas que vienen de la mano de mujeres cineastas gracias a su paulatina incorporación en la industria cinematográfica. El presente artículo analiza, bajo el marco de los Estudios Fílmicos y Estudios Feministas, la representación de la maternidad y la movilidad a través de la road movie Marsella (Belén Macias, 2014), en la que la maternidad de acogida y la maternidad de origen entran en tensión para profundizar en la diversidad y romper ideales sobre un escenario de movilidad que fuerza los límites de los personajes. Desde una mirada femenina, la película explora esa maternidad vivida en los denominados no lugares ante la búsqueda de la paternidad ausente, poniéndose de manifiesto el contraste entre dos concepciones diferentes bajo la misma esencia: la complejidad de la figura de la madre.
Netflix’s Maid and representations of masculinities through social class: a textual analysis.
Authors: Boehm Melissa
Published: January 2023

Maid, de Netflix, narra las luchas de una madre soltera blanca heterosexual que vive en el noroeste del Pacífico de Estados Unidos. Utilizando el concepto de masculinidades hegemónicas y el análisis textual cualitativo, este estudio examinó los 10 episodios de la serie para documentar la construcción social de las masculinidades de clase obrera y clase media. La vida disfuncional de clase trabajadora de Sean, con seis paquetes de cerveza y una caravana, se yuxtapone a la oferta de ordenada comodidad y seguridad de clase media suburbana de Nate. En mi opinión, el programa reafirma los estereotipos de los hombres de clase trabajadora y de clase media basados en sus hogares, trabajos, antecedentes familiares, actividades de ocio, y consumo de alcohol y drogas. Sean no respeta la autonomía corporal de Alex, su necesidad de independencia económica ni su necesidad de liberarse de los abusos emocionales. Del mismo modo, Nate es incapaz de ver más allá de su derecho hacia Alex basado en los beneficios materiales que le ofrece, como un vehículo prestado fiable, una casa limpia de dos plantas y paseos en poni para su hija. Sostengo que Alex, la protagonista principal, desafía las masculinidades hegemónicas para crear su propio espacio en el mundo sin las limitaciones dictadas por los hombres de su vida. Documentar cómo Maid cuenta la historia de una mujer y sus parejas sentimentales oprimidas por las masculinidades hegemónicas puede aportar información sobre las nociones de sentido común de las parejas sentimentales en los Estados Unidos de hoy.
Kepraktisan buku ajar berbasis higher order thinking skills (HOTS) pada mata kuliah pembelajaran matematika di sekolah dasar
Authors: Suganda M Vina Amilia , Toybah Toybah , Hawa Siti
Published: January 2023

Guru memiliki andil besar dalam mengarahkan agar siswa memiliki kemampuan matematika meliputi berpikir kritis, kreatif, kolaboratif dan komunikatif. Hal inilah yang melatarbelakangi untuk mempersiapkan mahasiswa PGSD sebagai calon guru di masa yang akan datang agar dapat mengembangan kemampuan tersebut pada siswa di SD, salah satunya dengan mengembangkan buku ajar berbasis Higher Order Thinking Skills (HOTS). Kegiatan penelitian ini merupakan bagian dari penelitian pengembangan dengan menggunakan model pengembangan  ADDIE untuk mengetahui kepraktisan bahan ajar berbasis HOTS.  Teknik pengumpulan data yaitu berupa angket, digunakan untuk mengumpulkan data dari subyek penelitian yaitu mahasiswa semester 3 (tiga) program studi PGSD FKIP Unsri. Setelah bahan ajar telah dinyatakan valid oleh ahli, selanjutnya menentukan kepraktisan bahan ajar melalui tahap uji coba one to one oleh 3 mahasiswa dan tahap small group oleh 9 mahasiswa. Diperoleh hasil penelitian menunjukkan bahwa rekaptulasi hasil angket kelompok one to one dan small group yaitu 88,5 persen dengan kategori kepraktisan sangat baik, artinya bahan ajar ini praktis digunakan.
A MATRIZ PARANOICA DO EU EM LACAN
Authors: Cardoso Rubens Díodoro Ferreira , Oliveira Gessé Duque Ferreira
Published: January 2023

Resumo: O presente ensaio objetiva demonstrar, através da obra de Jacques Lacan, como o Eu, enquanto unidade psíquica generalista marcada pela alienação e rivalidade, comporta uma dinâmica permeada por uma relação de similitude com os fenômenos presentes na psicose paranoica. Com este fim, buscou-se localizar a paranoia historicamente, bem como na obra freudiana, para então salientar a matriz paranoica do processo de constituição do Eu em Lacan. Trata-se, com isso, de uma tentativa de evidenciar o fundo paranoico em jogo no interior de todo funcionamento dito normal.Palavras-chave: Eu. Paranoia. Alienação. Lacan. Psicanálise.Abstract: This essay aims to demonstrate, through the work of Jacques Lacan, how the Self, as a generalist psychic unit marked by alienation and rivalry, has a dynamic permeated by a relationship of similarity with the phenomena present in paranoid psychosis. To this end, we sought to locate paranoia historically, as well as in Freud's work, to then highlight the paranoid matrix of the process of constitution of the Self in Lacan. It is, therefore, an attempt to highlight the paranoid background at play within all so-called normal functioning.Keywords: Self. Paranoia. Alienation. Lacan. Psychoanalysis.
Uma Análise sobre a Política Externa do Governo José Sarney a partir da Autonomia Relacional | An Analysis of the Foreign Policy of the José Sarney Government from the Perspective of Relational Autonomy
Authors: Ferreira Carlos Enrique Ruiz , Macedo Guilherme Fenicio Alves
Published: January 2023

O presente artigo objetiva analisar, através do conceito de autonomia relacional, a política externa do Governo José Sarney (1985-1990). A estrutura do artigo é composta por dois momentos: inicialmente, são apresentadas as definições e interpretações do conceito de autonomia nas relações internacionais e política externa e, em seguinte, é desenvolvida a aplicação conceitual da autonomia relacional sobre a política externa brasileira do Governo Sarney, tendo em conta 2 (duas) questões paradigmáticas deste período, a saber: a integração regional do MERCOSUL; a inserção do país na ONU, tendo em conta a agenda do Conselho de Segurança e dos Direitos Humanos. Palavras-Chave: Autonomia relacional; Política externa; José Sarney.ABSTRACT This article aims to analyze the foreign policy of the José Sarney Government (1985-1990) through the concept of relational autonomy. The structure of the article is composed of two moments: first, we presented the definitions and interpretations of the concept of autonomy in international relations and foreign policy. Secondly, we developed the conceptual application of relational autonomy on the Brazilian foreign policy of  Sarney’s Government, taking into account 2 (two) paradigmatic issues of this period, namely: the regional integration of MERCOSUR and the insertion of the country in the UN, with emphasis on the Security Council and the Human Rights agenda. Keywords: Relational Autonomy; Foreign Policy; José Sarney.Recebido em: 30 abr. 2022 | Aceito em: 12 dez. 2022.
Blowing bubbles for storage
Authors: FOWLER DAVID
Published: January 2023

Energy storage material takes shape in Nottingham
Armoured vehicle contract to safeguard British jobs
Authors: FORD JASON
Published: January 2023

Contract calls for over 500 UK-built armoured vehicles
ACCESS ALL AREAS
Authors: EXCELL JON
Published: January 2023

CMR Surgical’s Versius robot is poised to bring the benefits of keyhole surgery to the masses.
Grain Power
Authors: FORD JASON
Published: January 2023

The Engineer reports on a key innovation from the food processing industry
REE INVESTS IN UK CENTRE OF EXCELLENCE
Authors: FORD JASON
Published: January 2023

A new Engineering Centre of Excellence could eventually create around 200 highly skilled jobs following REE Automotive’s decision to invest $92m in the UK.
space Launch partner named
Authors: Ford Jason
Published: January 2023

UK ambitions to be Europe’s first launch site for small satellites have moved forward with confirmation of ABL Space Systems’ vehicle for launches.
Made for the air and ready for the sea
Authors: Ford Jason
Published: January 2023

An international peace treaty could not stop the development of a flying boat equipped with a mast and sails
Boreholes could house UK’s nuclear waste
Authors: FORD JASON
Published: January 2023

A combination of drilling techniques could save billions in storage costs
Why oil and gas engineers should consider a career in hydrogen
Authors: IRELAND BILL
Published: January 2023

As net zero beckons career opportunities in oil and gas are not what they used to be. But engineers working in the industry are well placed to pursue a new career in the burgeoning hydrogen sector writes Bill Ireland, CEO of Logan Energy
THALES SECURES FUNDING FOR COREF PROJECT
Authors: BRADSHAW MELISSA
Published: January 2023

Thales is to lead COREF, a new manufacturing project that will receive funding through the government's Aerospace Technology Institute Programme.
Rudolf Diesel: Powering the Modern World
Authors: Smith Nick
Published: January 2023

With the development of his eponymous engine, Rudolf Diesel was to have a profound effect on the way industry, transportation and international freight shaped the 20th century.
Patients on a plane
Authors: FORD JASON
Published: January 2023

Airliners proposed for Covid-19 therapy
MET POLICE RECRUIT NEOFACE
Authors: FORD JASON
Published: January 2023

Facial recognition system used to collar criminals
Additive Manufacturing: a mature technology?
Authors: HAGUE RICHARD
Published: January 2023

Additive International’s chair, Professor Richard Hague addresses the shift from conventional AM as an ‘emerging’ technology to a more established one – and the importance of research in avoiding its stagnation and advancing the potential of next generation, multi-material AM.
MTC Joins Space Energy Initiative for In-Orbit Solar
Authors: Wade Andrew
Published: January 2023

The Manufacturing Technology Centre is set to play a leading role in the UK’s new Space Energy Initiative, which is aiming to develop in-space solar energy technology.
Q&A: Taking Control of The Drive Forward
Authors: Ford Jason
Published: January 2023

The evolving factory ecosystem calls for new solutions. Experts from the world of drives and controls and automation discuss some of the key trends
UK set for industrial scale battery recycling
Authors: FORD JASON
Published: January 2023

London company to bring batteries into the circular economy
Terraforming the earth
Authors: POWELL GARETH L.
Published: January 2023

As Net Zero technology is a current hot topic in the engineering industry, our resident sci-fi author Gareth L. Powell takes a look at some more extreme solutions to the climate crisis.
Charged for Flight
Authors: Ford Jason
Published: January 2023

The global race to decarbonise transport will see the introduction of a new form of aircraft powered by electricity and inspired by fixed wing and rotorcraft
Jingye Group pledges £1.2bn investment into British Steel
Authors: FORD JASON
Published: January 2023

Completion of acquisition secures approximately 3,200 jobs
Register Now for July's Additive International Summit
Authors: Excell Jon
Published: January 2023

Running from 13th – 14th July at Nottingham's Albert Hall, the Additive International summit provides a unique opportunity to hear from industry and academic researchers at the forefront of additive manufacturing technology.
Cleaning up our Clusters
Authors: Bradshaw Melissa
Published: January 2023

The UK is on course to deliver the first ever net zero industrial cluster by 2040. But what will the reality of a cluster future look like for Britain?
June 1919 Versatile Vimy
Authors: Ford Jason
Published: January 2023

Originally designed as a bomber, the record-breaking Vickers Vimy was reconfigured for passenger flight
Europe's First 3D Printed Vehicle Unveiled
Authors: Ford Jason
Published: January 2023

Vehicle produced during lockdown to demonstrate capabilities
Why Engineering should be Viewed as a Caring Profession
Authors: Edmondson Stewart , Al-Hashimi Bashir M.
Published: January 2023

In order to inspire the next generation of engineers, we must ensure that the curriculum reflects the ways in which engineering addresses the big global challenges write Professors Bashir M. Al-Hashimi and Stewart Edmondson
Ploughing Ahead
Authors: Ford Jason
Published: January 2023

The mechanisation of arable farming started with complex and cumbersome steam-driven ploughs
Investors Indulge in Cheesecake
Authors: Ford Jason
Published: January 2023

Seed funding to accelerate green energy storage solution
Q&A: Two Wheels Good
Authors: Excell Jon
Published: January 2023

WIth the use of e-scooters rising rapidly, experts from some of the key UK trials comment on the technology’s potential.
As you Like it
Authors: Allcock Andrew
Published: January 2023

MCM’s distinctive horizontal machining centre-based solutions are now available through RK International Machine Tools. Single-source, customer-adapted, fully- engineered automated solutions mark it out from the crowd.
Fighting Spirit
Authors: Ross Matt
Published: January 2023

As OEM’s struggled under war-time gasoline restrictions, Peugeot’s engineers opted for an electric city car solution
Riding High
Authors: Poultney Leon
Published: January 2023

Could improvements in battery technology combined with stricter emissions restrictions and increasing demand for cheaper personal transport see the rise of the electric motorcycle?
The Sky’s the Limit
Authors: Allan Keri
Published: January 2023

The huge developmental push for electric aircraft is driving investment in laboratories and equipment to test high power electrical systems
Commercial Sense
Authors: Challen John
Published: January 2023

With capacity at a new production site in Coventry, UK, the London Electric Vehicle Company is looking firmly beyond its iconic black taxi cab
Evolutionary Road
Authors: Billington James
Published: January 2023

Leaders within the electric vehicle industry share their thoughts on how the market has changed over the past 25 years, and what they anticipate will be next big thing for the future of alternative energy mobility
Silver Linings
Authors: Grant Alex
Published: January 2023

The sudden onset of Covid-19 has caused unprecedented disruption to the automotive industry, but could electrification be the key to economic recovery as we strive for a ‘new normal'?
Modern classics
Authors: Challen John
Published: January 2023

An emerging sector of the electric vehicle market is in overhauling classic ICE cars to make them run on batteries, but is the process as simple as plug and play?
Solid Potential Anode Solid Electrolyte Cathode
Authors: Millard Frank
Published: January 2023

What does solid-state battery technology have in store, and will it facilitate the electric vehicle revolution which the industry hopes and expects?
Hydrogen vs Electric
Authors: Millard Frank
Published: January 2023

Lift-trucks are almost the original electric vehicle, with many models powered for decades by lead-acid batteries. But now, even with the new benefits offered by lithium-ion, there is a fresh challenger to battery electric dominance - increasingly affordable hydrogen fuel-cell solutions
Indian Ambition
Authors: Challen John
Published: January 2023

As the second most populated country in the world, with the fifth largest car market, India offers mouth-watering opportunity for electrification on the roads but there are high hurdles to overcome in its aggressive push to revolutionize its entire mobility sector
What Lies Beneath
Authors: Vadaszffy Karl
Published: January 2023

When it comes to electric and hybrid vehicles, marginal gains in performance materials can make all the difference
Natural Selection
Authors: Billington James
Published: January 2023

The development of a sustainable and efficient electric concept sports car is hoping to inspire change within the automotive industry with a message that the car of tomorrow’s performance won’t be measured by its acceleration and top speed
Shifting Sands
Authors: Gooding Richard
Published: January 2023

Zero emission motorsport is fast picking up pace, and now the Dakar Rally endurance event is also entering the electrified age. However, it’s not just electric and hybrid powertrains that will duel in the harsh desert. The arrival of hydrogen-powered vehicles is an important step in the series’ clean-energy transition
Best of the Test
Authors: Challen John
Published: January 2023

We explore the UK’s growing network of electric vehicle proving grounds and test sites to see what sort of cutting-edge technologies they offer to help OEMs keep-up with demand
Life-Changing Experience
Authors: Loveridge Melanie , Bhagat Rohit
Published: January 2023

Research into 2D materials, led by the University of Warwick’s Energy Innovation Centre, could have significant implications for the lifespan of rechargeable lithium-ion batteries in electric vehicle applications
Platform Building
Authors: Crosse Jesse
Published: January 2023

A modular platform will be central to PSA ’s new model range, and key to the OEM’s plans for electrification
Joined-up Thinking
Authors: Pickering Chris
Published: January 2023

E&H Vehicle takes a look at why e-axles are forecast to be the fastest-growing driveline technology in electric and hybrid vehicles
Power Trip
Authors: Evans John
Published: January 2023

When designing an electric powertrain, vehicle OEMs are faced with a plethora of choices with regard to the type, number and location of electric motors. Leading developers have their say on the debate
Taking Flight
Authors: Ross Matt
Published: January 2023

What started out as a low-emissions vehicle project at the UK’s Coventry University has developed into a fledgling car manufacturer with plans to build a niche, low-volume, all-electric sports car
The Final Frontier
Authors: Grant Alex
Published: January 2023

British startup Fering has developed a lightweight, modular all-terrain truck platform, which will enable organizations in the world's harshest environments to electrify their fleets
Spirit of Innovation
Authors: Sampson Ben
Published: January 2023

As the electric aircraft sector takes off, the world's fastest electric plane borrows technology and testing methods from the automotive sector to realize the potential of battery-powered flight
Elemental Efficiency
Authors: Gooding Richard
Published: January 2023

Steadily replacing silicon in the drive motors, inverters, and power electronics of electric vehicles, silicon carbide offers increased operating temperatures and enhanced efficiency. What other properties of this new wonder material are raising its profile and popularity?
Flag in the Ground
Authors: Fortune Kyle
Published: January 2023

To keep up with the demand for new models, Polestar is expanding operations into the UK where it has setup base in the heart of the country to develop and build the brand's prototypes, including a bespoke platform for the forthcoming Polestar 5
Breaking New Ground
Authors: Grant Alex
Published: January 2023

A UK consortium has begun a three-year project aiming to commercialize a low-cost, rare-earth-free motor technology, with Bentley in line for its first application
Smooth Operators
Authors: Clymo Rob
Published: January 2023

Times are changing for oil companies, so will the advent of e-lubricants and e-greases be their saviour?
Full Spectrum Warfare
Authors: Sampson Ben
Published: January 2023

As the importance of electronic warfare increases, testing technology is coming out of the lab for use on front-line aircraft
Fantastic Four
Authors: Beever Paul
Published: January 2023

Dynamics expert Paul Beever discusses various aspects of steer-by-wire and all-wheel-steering setups, and how they could be enhanced for greater driving pleasure and safety
Around the Regions: The South West
Authors: Tulip Stephen
Published: January 2023

In its regular column, Make UK profiles the work done in the sector across the country – this time taking in the South West, where companies ranging from Airbus to Dyson are making significant strides with the latest technology
A capital idea
Authors: Lockhart Jim
Published: January 2023

Manufacturers looking to grow are able to take better advantage of capital allowances following a change in regulations
SALT OF THE EARTH
Authors: Beck Chris
Published: January 2023

Balancing aging assets in a 50-year-old site with increasing customer demand and a volatile market required the team at British Salt’s Cheshire factory take some bold steps to modernise
BUILDING STRONG FOUNDATIONS
Authors:   CONTRIBUTOR OCHIBA BUSINESS SOLUTIONS
Published: January 2023

ERP Implementation: The Technology Driver for Industry 4.0 and how to make it a reality
Finding a Balance
Authors: Lentz Debbie
Published: January 2023

COVID-19 seriously disrupted supply chains throughout industry worldwide, exposing today’s necessity for supply chain resilience and continuity. However, some companies fared better than most by consolidating their suppliers
Smart Steps
Authors: Loughran Mike
Published: January 2023

With the increased need for fully connected and flexible systems, SMEs are now proactively looking to technology to optimise production processes
Untapped Value Hiding in Untapped Data
Authors: Graham Andy
Published: January 2023

In the third in a series of articles for MM, SolutionsPT shows how there is value to be had within the factory through untapped data
Battling Bias
Authors: Paul Kelly
Published: January 2023

Have you ever found yourself favouring one employee over another? Then you’ve been the victim of an unconscious bias
Making your Voice Heard
Authors: Beck Chris
Published: January 2023

Make UK’s CEO, Stephen Phipson, speaks to Manufacturing Management about the fallout from the general election, wider industry pressures and the National Manufacturing Conference
Trading Places
Authors: Baal Alexander
Published: January 2023

Warehouse managers can be reticent to look at second-hand forklifts, preferring to buy new. However, a used option is often just as good as the original
British Racing Green
Authors: Beck Chris
Published: January 2023

Bentley Motors’ historic Crewe factory has become a flagship for high-quality, sustainable manufacturing. MM takes a look inside to discover its secrets
Clean Savings
Authors: Beck Chris
Published: January 2023

Unilever’s washing tablet factory in Port Sunlight has turned to Festo to undertake a root-and-branch audit of the site’s energy usage
Employment Law SOS
Authors: Robins Caroline
Published: January 2023

This month, our legal expert looks at how to deal with disruptive employee who is threatening legal action based on his race, and explores whether regional discrimination is classified as an offence
Special Delivery
Authors: Beck Chris
Published: January 2023

Royal Mail has implemented a raft of automation solutions to help improve its efficiency – and has benefitted to the tune of £4.5 million in 2018/19 alone
Breaching the Perimeter
Authors: Beck Chris
Published: January 2023

Lockdown has seen an unprecedented spike in cyberattacks on UK manufacturers, leading to fears that the industry may not be prepared for a breach in its systems
A hidden threat
Authors: Bandos Tim
Published: January 2023

Manufacturing is a prime target for cyber criminals, but companies can employ a range of methods to protect themselves and their IP
Space saver
Authors: Purvis Steve
Published: January 2023

As the pandemic forces companies to re-think their supply chains and stock holdings, could a new way of thinking about warehousing space be the answer?
Beyond the Buzzword
Authors: Beck Chris
Published: January 2023

It’s high time for Industry 4.0 to move beyond a concept and onto the shopfloor
Critical Thinking
Authors: Bernstein Adam
Published: January 2023

Managers should consider the benefits of Business Continuity Planning to build confidence throughout their organisation
In Case of Emergency
Authors: Beck Chris
Published: January 2023

A lack of understanding of the importance of even the most basic first aid is putting lives at risk in the workplace
Unlocking a better Way
Authors: Beck Chris
Published: January 2023

Effective analysis of data is key to increasing production and minimising downtime. A new AI-based approach from Atlas Copco is looking to take this to the next level
A Standard Way to Automation
Authors: Beck Chris
Published: January 2023

Manufacturing Management speaks to Martin Ahner, project engineer at norelem about how automation can be simplified by using standard components in the installation process
Making our Future
Authors: BECK CHRIS
Published: January 2023

Make UK’s National Manufacturing Conference returned to Westminster and brought together industry leaders, politicians and academia for a day of networking and high-level debate
Seize the Day, Seize the Opportunity
Authors: CROZIER ROWAN
Published: January 2023

Brexit has delivered more costs, more paperwork and more challenges, but, once you look past the initial pain, there are many opportunities for UK manufacturing
A Shot in the Arm
Authors: BECK CHRIS
Published: January 2023

Strong sales and record interest marked the return of the MACH exhibition after four years away, as the leading names in the sector demonstrated the latest manufacturing technology
Operating at Full Capacity
Authors: Purvis Steve
Published: January 2023

With a Brexit extension until Halloween, will the extra time reduce the risks, or merely extend the period of uncertainty for manufacturers?
When Automation Meets Craftsmanship
Authors: Beck Chris
Published: January 2023

Traditional, skilled manufacturing and high-tech automation can often appear to be strange bedfellows. However, smart manufacturers should look to marry the two
Soldering On
Authors: Ferguson Michelle
Published: January 2023

As part of Royal British Legion Industries, Scotland’s Bravest Manufacturing Company had to balance staff wellbeing with boosting production during the pandemic
Welding People and Automation
Authors: Beck Chris
Published: January 2023

Sheet metal volume manufacture and fabrication specialists, Contracts Engineering, entered 2020 with an increasing demand for its services. In order to boost productivity and meet this rise in orders, it made its first foray into the world of welding automation
Through the Mill
Authors: Beck Chris
Published: January 2023

A new digital procurement service is hoping to revolutionise and rejuvenate the UK’s steel industry and bring the entire value chain into the 21st century