bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of Drones in Cadastral Works and Precision Works in Silviculture and Agriculture
Authors: Călina Jenica , Călina Aurel , Miluț Marius , Croitoru Alin , Stan Ion , Buzatu Claudiu
Published: June 2023

A new technology based on GPS and aerophotographic determinations has begun to be used on a larger scale. Currently many tractors and machines are equipped with such technology, which allows the owners and administrators of agricultural land to practice a modern agriculture called “precision agriculture”. Our approach deals with two very important aspects regarding the agricultural and forest areas, namely the cadastral records and inventory and the precision works. Regarding the preparation of the topo-cadastral documentation it was very clear and relevant that the technology of aerophotography with the help of drones, is as accurate and faithful as the classic one (that is to say on the ground), only that its efficiency is much higher. Also, it has been shown very clearly that this technology has many advantages, as it allows the construction of a database, with which the forestry and agricultural specialists can easily and quickly generate a series of thematic maps that will facilitate very much their management activity. Following the researches, it was found that in the future agriculture and forestry will use drones on a larger scale, as they allow obtaining data and information in real time, as opposed to satellites, and the clarity of the images and the accuracy of the data is significantly higher, contributing greatly to modern management practice and performance, in which decisions can be made quickly and very efficiently documented.
THE INFLUENCE OF REWARD SYSTEM ON EMPLOYEE JOB SATISFACTION WITH WORK MOTIVATION AS INTERVENING VARIABLES (Case Study on Employees of Medical Department United States)
Authors: Stephen Martinr  , Martin Uribe
Published: June 2023

This study aims to determine“The Influence of the Reward System on Employee Job Satisfaction with Work Motivation as an Intervening Variable (Case Study of Employees of Medical Department United States)
THE INFLUENCE OF WORK DISCIPLINE AND WORKLOAD ON EMPLOYEE PERFORMANCE (Study on Community Empowerment for Helath Service Employees At California District)
Authors: John Zysman  , Arnaud Costinot
Published: June 2023

This study aims to determine"The Influence of Work Discipline and Workload on Employee Performance(Study on Community Empowerment for Helath Service Employees). The results of this study indicate that 1) it can be seen that tcount (1,959) < ttable (2.045), likewise with a significance value of 0,060> 0.05 it can be concluded hypothesisfirst denied, meaningWork Discipline Variable (X1) has no significant effect on Employee Performance Variable (Y). 2)it can be seen that tcount (1.023) < ttable (2.045), and a significance value of 0.315 > 0.05, it can be concluded that the second hypothesis is rejected, meaningWorkload Variable (X2) has no positive and significant effecton Employee Performance Variables (Y) .3) it can be seen that Fcount (10.247) > Ftable (3.34), and a significance value of 0,000<0.05, it can be concluded that the fourth hypothesis is accepted, meaningWork Discipline Variable (X1), Workload Variable (X2), have a significant simultaneous effect on Employee Performance Variable (Y).
RELATIONSHIP BETWEEN HEALTH BEHAVIORS AND INCIDENT OF DENGUE FEVER AND DHF IN THEWORKING AREA OF SINGOSARI PEMATANG SIANTAR HEALTH CENTER
Authors: Shofian Syarifuddin  , Wilson Samosir
Published: June 2023

The background in this study is that Dengue Hemorrhagic Fever (DHF) is a public health problem in Indonesia, since 1968 the number of cases has tended to increase and its spread has become wider. The incidence of Dengue Hemorrhagic Fever (DHF) in the working area of ​​the Pematang Raya Health Center in 2008 was recorded as many as 91 cases with 2 fatalities. From the data obtained, it is known that there was a significant increase in the incidence of Dengue Hemorrhagic Fever (DHF) from year to year between 2004-2008. The purpose of this study was to determine what health behaviors were associated with the occurrence of Dengue Hemorrhagic Fever (DHF) in the working area of ​​the Pematang Raya Public Health Center. This type of research was an analytic survey study using a case-control approach. The population in this study were Dengue Hemorrhagic Fever sufferers (cases) and not Dengue Hemorrhagic Fever sufferers (controls). A sample of 40 cases and 40 controls were obtained using simple random sampling technique. The instruments used in this study were 1) questionnaires, 2) data on DHF patients at the Pematang Raya Health Center and DKK Kendal. The data for this study were obtained from primary data, in the form of interview results, and secondary data in the form of DHF patients at the Pematang Raya Health Center and DKK Kendal. The data obtained in this study were analyzed using the Chi-square statistical test formula and the determination of the Odds Ratio (OR). From the research results it was found that the significant factors were: cleaning the water reservoir (p value-0.044, OR=2.513), closing the water reservoir (p value 0.002, OR=4.333), draining water reservoirs (p value 0.004, OR=3.857), burying used goods (p value 0.014, OR-3.095), throwing garbage in its place and burning it (p value-0.043, OR=2.538), hanging clothes (p value=0.001, OR=4.896), and use mosquito repellent lotion (p value=0.002, OR=6.000). From the results of the research and discussion, it can be concluded that health behaviors related to the incidence of Dengue Hemorrhagic Fever (DHF) in the 2018 Pematang Raya Health Center work area, namely cleaning water reservoirs, closing water reservoirs, draining water reservoirs, burying used goods , throwing trash in its place and burning it, hanging clothes, and wearing mosquito repellent.
THE EFFECT OF ONLINE ADVERTISING ON CONSUMER BUYING INTEREST IN ONLINE SELLING APPLICATIONS WITH CUSTOMER SATISFACTION AS AN INTERVENING VARIABLE (Case Study of Medical Doctor and Nurses in Chicago)
Authors: Mark G. Maffett  , Jorge O. Brusa
Published: June 2023

The results of this study show. (1) It can be seen that the value of the adjusted R square is 0.758 or 75.8%. This shows that consumer satisfaction (Y1) and advertising (X) can explain purchase intention (Y2) of 75.8%, the remaining 24.2% (100% - 75.8%) is explained by other variables outside the research model. This. Such as service, price and interest in buying. (2) The results of the (Partial) t test show that tcount (7.413) > ttable (1.685), likewise with a significance value of 0.00 <0.05, it can be concluded that the first hypothesis is accepted, meaning that the advertising variable (X) has an effect positive and significant to consumer satisfaction (Y1). (3) The results of the t test (Partial) can be seen that the value of tcount (3.059) > ttable (1.685), and the significance value is 0.00 <0.05, it can be concluded that the second hypothesis is accepted, meaning that advertising (X) has a positive and significant effect on purchase intention (Y2). (4) The results of the path analysis test show that the direct effect of variable X on variable Y2 is 0.377. While the indirect effect through the Y1 variable is 0.769 x 0.554 = 0.426, the calculation results obtained show that the indirect effect through the Y1 variable is greater than the direct effect on the Y2 variable.
Nickel as a key element in the future energy
Authors: Savina A. A. , Boev A. O. , Orlova E. D. , Morozov A. V. , Abakumov A. M.
Published: June 2023

The review discusses the complex properties of nickel and its role as a critical element for ensuring a confident transition to a new technological paradigm from fossil fuels in favor of using advanced electrochemical storage and energy conversion systems. The main classes of nickel-containing materials of the positive electrode (cathode) for metal-ion batteries are discussed, the place of nickel among other 3d-metals used in the industry of electrochemical energy storage is determined. The main methods and approaches for the synthesis of state-of-the-art and next generation cathode materials based on layered Ni-containing oxides are presented. The crystal and electronic structures of these materials, including their evolution in the process of (de)intercalation of alkali metal cations, are considered in the context of their electrochemical properties. The most acute problems facing modern materials science on the way to commercialization and industrial production of new generation highenergy density cathode materials are determined. At the end of the review, promising directions for the further development of nickelcontaining cathode materials are outlined.
 The bibliography includes 252 references.
FRICTIONAL PRESSURE DROP DURING CONDENSING FLOW INSIDE MINI/MICRO-CHANNELS: PREDICTIVE TOOLS ASSESSMENT AND DATA TREATMENT
Authors: RAMIREZ RIVERA FRANCISCO ALBERTO , GUERRERO RODRIGUEZ NESTOR , GARCIA FROMETA YOKASTA INMACULADA , SANCHEZ GARCIA ALISON
Published: June 2023

A total of 1210 new condensation friction pressure gradient points (database) is collected from 12 open articles on mini/micro-channels literature. The database covered a wide range of thermophysical properties associated with low-GWP refrigerants, physical dimension, mass velocity and vapor quality. A comparison of the experimental database against eleven two-phase flow frictional pressure drop prediction tools is carried out. Based on that, the mini/micro-channel developed by Xu and Fang exhibited the best ability to capture the tendency of the database with a mean absolute relative deviation of (36.59%) for all data.

Keywords: Two-phase flow frictional pressure gradient; Mini/micro-channels; Condensing flow; New refrigerant fluid; Heat transfer; Collect database.
On principal value and standard extension of distributions
Authors: Barlet Daniel
Published: June 2023

For a holomorphic function $f$ on a complex manifold $\mathscr {M}$ we explain in this article that the distribution associated to $\lvert  f\rvert^{2\alpha } (\textrm{Log} \lvert f\rvert^2)^q f^{-N}$ by taking the corresponding limit on the sets $\{ \lvert f\rvert \geq \varepsilon \}$ when $\varepsilon $ goes to $0$, coincides for $\Re (\alpha ) $ non negative and $q, N \in \mathbb {N}$, with the value at $\lambda = \alpha $ of the meromorphic extension of the distribution $\lvert f\rvert^{2\lambda } (\textrm{Log} \lvert f\rvert^2)^qf^{-N}$. This implies that any distribution in the $\mathcal {D}_{\mathscr {M}}$-module generated by such a distribution has the standard extension property. This implies a non $\mathcal {O}_\mathscr {M}$ torsion result for the $\mathcal {D}_{\mathscr {M}}$-module generated by such a distribution. As an application of this result we determine generators for the conjugate modules of the regular holonomic $\mathcal {D}$-modules introduced and studied in [Barlet, D., On symmetric partial differential operators, Math. Z. 302 (2022), no. 3, 1627–1655] and [Barlet, D., On partial differential operators which annihilate the roots of the universal equation of degree $k$, arXiv:2101.01895] associated to the roots of universal equation of degree $k$, $z^k + \sum _{h=1}^k (-1)^h\sigma _hz^{k-h} = 0$.
Patients’ experiences of termination of pregnancy at a regional hospital in Durban, South Africa
Authors: Mbona V , Kistan G , Sebitloane H M
Published: June 2023

Background. Safe and effective termination of pregnancy (ToP) services have helped to resolve the uncertainty that surrounds unwantedpregnancies globally and in South Africa (SA). It is important to determine the demographic profile of women requesting ToP and to assessthe reasons for ToP and the beliefs and experiences of women seeking these services in order to improve service delivery.Objectives. To determine the sociodemographic profile and emotional and psychological experiences of women undergoing ToP at aregional hospital in Durban, SA.Methods. The study population consisted of women seeking either medical or surgical ToP at the Addington Hospital ToP clinic from Juneto August 2021. The participants were requested to complete a structured self-reporting questionnaire on their sociodemographics, theirawareness of, attitude to and knowledge of ToP, and their reasons for seeking ToP services, as well as contraception method and use. Thequestionnaire also captured their experience after the ToP was completed.Results. Of the 246 participants, the majority (92.3%) were aged 16 - 35 years, with 62.6% having little or no income and dependent ontheir family or partner for financial support. Most of the participants (73.2%) were parous and had secondary education and above (94.3%).Furthermore, 59.0% of the participants indicated they were not on any form of contraception before becoming pregnant, even though 70.3%of them were single. The most cited reasons for ToP were lack of finance (37.5%), schooling (33.9%), and not feeling ready to be a parent(20.0%). Although some participants (35.7%) were fearful of ToP, most of them (78.0%) reported feeling relieved after the procedure.Conclusion. Unemployment and financial dependency appeared to be common reasons for seeking ToP in our study population. Most ofthe women were single and many had not used any contraception prior to the pregnancy.
Investigating blood alcohol concentrations in injury-related deaths before and during the COVID-19 National lockdown in Western Cape, South Africa: A cross-sectional retrospective review
Authors: Bachan V , Molefe I , Davies B
Published: June 2023

Background. Alcohol is a significant contributor to injury-related morbidity and mortality in South Africa (SA).  During the COVID-19 global pandemic, restrictions to movement and to the legal access of alcohol* were introduced in SA.  This study aimed to investigate the effect of alcohol bans during the COVID-19 lockdown periods on injury-related mortality and the blood alcohol concentrations (BAC) in these deaths.
Methods. A retrospective, cross-sectional analysis of injury-related deaths in Western Cape (WC) province, SA, between 1 January 2019 to 31 December 2020 was conducted. Cases where BAC testing was performed were further examined according to the periods of lockdown (AL5-1) and alcohol restrictions.
Results. A total of 16,027 injury-related cases were admitted to Forensic Pathology Service mortuaries in the WC over the two-year period.  An average decrease of 15.7% injury-related deaths in 2020 compared to 2019 was noted, as well as a 47.7% decrease in injury-related deaths during hard lockdown (April -May 2020) compared to the same period in 2019. In the injury-related deaths, 12,077 (75.4%) had blood specimens collected for BAC testing. In 5,078 (42.0%) of submitted cases, a positive BAC (≥0.01g/100 mL) was reported. No significant difference was observed in the mean positive BAC between 2019 and 2020, however in April and May 2020, the mean BACs observed (0.13 g/100 mL) was less than that in 2019 (0.18 g/100 mL). A high number of positive BACs in the 12-17-year age group (±23.4%) was observed.
Conclusion. There was a clear decrease in injury-related deaths in the WC during the COVID-19-related lockdown periods that coincided with the alcohol ban and restriction of movement and an increase following relaxation of restrictions on alcohol sales and movement. The data illustrated that mean BACs were similar between all periods of alcohol restriction compared to 2019, apart from hard lockdown in April-May, 2020.  This coincided with a smaller mortuary intake during the level 5 and 4 lockdown periods.  
Keywords: Alcohol; blood alcohol concentration; COVID-19; injury; lockdown; South Africa; violent death; Western Cape
 
* Alcohol refers to ethanol
A note on a generalization of Riordan’s combinatorial identity via a hypergeometric series approach
Authors:   Department of Mathematics Education, Andong National University, Lim Dongkyu
Published: June 2023

In this note, an attempt has been made to generalize the well-known and useful Riordan’s combinatorial identity via a hypergeometric series approach.
Model discovery to link neural activity to behavioral tasks
Authors: Costabile Jamie D , Balakrishnan Kaarthik A , Schwinn Sina , Haesemeyer Martin
Published: June 2023

Brains are not engineered solutions to a well-defined problem but arose through selective pressure acting on random variation. It is therefore unclear how well a model chosen by an experimenter can relate neural activity to experimental conditions. Here, we developed ‘model identification of neural encoding (MINE).’ MINE is an accessible framework using convolutional neural networks (CNNs) to discover and characterize a model that relates aspects of tasks to neural activity. Although flexible, CNNs are difficult to interpret. We use Taylor decomposition approaches to understand the discovered model and how it maps task features to activity. We apply MINE to a published cortical dataset as well as experiments designed to probe thermoregulatory circuits in zebrafish. Here, MINE allowed us to characterize neurons according to their receptive field and computational complexity, features that anatomically segregate in the brain. We also identified a new class of neurons that integrate thermosensory and behavioral information that eluded us previously when using traditional clustering and regression-based approaches.
Metabolic consequences of various fruit-based diets in a generalist insect species
Authors: Olazcuaga Laure , Baltenweck Raymonde , Leménager Nicolas , Maia-Grondard Alessandra , Claudel Patricia , Hugueney Philippe , Foucaud Julien
Published: June 2023

Most phytophagous insect species exhibit a limited diet breadth and specialize on a few or a single host plant. In contrast, some species display a remarkably large diet breadth, with host plants spanning several families and many species. It is unclear, however, whether this phylogenetic generalism is supported by a generic metabolic use of common host chemical compounds (‘metabolic generalism’) or alternatively by distinct uses of diet-specific compounds (‘multi-host metabolic specialism’)? Here, we simultaneously investigated the metabolomes of fruit diets and of individuals of a generalist phytophagous species, Drosophila suzukii, that developed on them. The direct comparison of metabolomes of diets and consumers enabled us to disentangle the metabolic fate of common and rarer dietary compounds. We showed that the consumption of biochemically dissimilar diets resulted in a canalized, generic response from generalist individuals, consistent with the metabolic generalism hypothesis. We also showed that many diet-specific metabolites, such as those related to the particular color, odor, or taste of diets, were not metabolized, and rather accumulated in consumer individuals, even when probably detrimental to fitness. As a result, while individuals were mostly similar across diets, the detection of their particular diet was straightforward. Our study thus supports the view that dietary generalism may emerge from a passive, opportunistic use of various resources, contrary to more widespread views of an active role of adaptation in this process. Such a passive stance towards dietary chemicals, probably costly in the short term, might favor the later evolution of new diet specializations.
Endoparasitoid lifestyle promotes endogenization and domestication of dsDNA viruses
Authors: Guinet Benjamin , Lepetit David , Charlat Sylvain , Buhl Peter N , Notton David G , Cruaud Astrid , Rasplus Jean-Yves , Stigenberg Julia , de Vienne Damien M , Boussau Bastien , Varaldi Julien
Published: June 2023

The accidental endogenization of viral elements within eukaryotic genomes can occasionally provide significant evolutionary benefits, giving rise to their long-term retention, that is, to viral domestication. For instance, in some endoparasitoid wasps (whose immature stages develop inside their hosts), the membrane-fusion property of double-stranded DNA viruses have been repeatedly domesticated following ancestral endogenizations. The endogenized genes provide female wasps with a delivery tool to inject virulence factors that are essential to the developmental success of their offspring. Because all known cases of viral domestication involve endoparasitic wasps, we hypothesized that this lifestyle, relying on a close interaction between individuals, may have promoted the endogenization and domestication of viruses. By analyzing the composition of 124 Hymenoptera genomes, spread over the diversity of this clade and including free-living, ecto, and endoparasitoid species, we tested this hypothesis. Our analysis first revealed that double-stranded DNA viruses, in comparison with other viral genomic structures (ssDNA, dsRNA, ssRNA), are more often endogenized and domesticated (that is, retained by selection) than expected from their estimated abundance in insect viral communities. Second, our analysis indicates that the rate at which dsDNA viruses are endogenized is higher in endoparasitoids than in ectoparasitoids or free-living hymenopterans, which also translates into more frequent events of domestication. Hence, these results are consistent with the hypothesis that the endoparasitoid lifestyle has facilitated the endogenization of dsDNA viruses, in turn, increasing the opportunities of domestications that now play a central role in the biology of many endoparasitoid lineages.
Diminishing neuronal acidification by channelrhodopsins with low proton conduction
Authors: Hayward Rebecca Frank , Brooks F Phil , Yang Shang , Gao Shiqiang , Cohen Adam E
Published: June 2023

Many channelrhodopsins are permeable to protons. We found that in neurons, activation of a high-current channelrhodopsin, CheRiff, led to significant acidification, with faster acidification in the dendrites than in the soma. Experiments with patterned optogenetic stimulation in monolayers of HEK cells established that the acidification was due to proton transport through the opsin, rather than through other voltage-dependent channels. We identified and characterized two opsins which showed large photocurrents, but small proton permeability, PsCatCh2.0 and ChR2-3M. PsCatCh2.0 showed excellent response kinetics and was also spectrally compatible with simultaneous voltage imaging with QuasAr6a. Stimulation-evoked acidification is a possible source of disruptions to cell health in scientific and prospective therapeutic applications of optogenetics. Channelrhodopsins with low proton permeability are a promising strategy for avoiding these problems.
Establishing And Maintaining The Blood-Brain Barrier: Epigenetic And Signaling Determinants
Authors: Sadanandan Jayanarayanan , Thomas Sithara , Mathew Iny Elizabeth , Huang Zhen , Blackburn Spiros L , Tandon Nitin , Lokhande Hrishikesh , McCrea Pierre D , Bresnick Emery H. , Dash Pramod K , McBride Devin , Harmanci Arif , Jose Dania , Dienel Ari C , Zeineddine Hussein A , Hong Sungha , Peeyush Kumar T
Published: June 2023

The blood-brain barrier (BBB) controls the movement of molecules into and out of the central nervous system (CNS). Since a functional BBB forms by mouse embryonic day E15.5, we reasoned that gene cohorts expressed in CNS endothelial cells (EC) at E13.5 contribute to BBB formation, whereas adult gene signatures reflect BBB maintenance mechanisms. Supporting this hypothesis, transcriptomic analysis revealed distinct cohorts of EC genes during BBB formation and maintenance. Here we demonstrate that epigenetic regulator’s histone deacetylase 2 (HDAC2) and polycomb repressive complex 2 (PRC2) control EC gene expression for BBB development and prevented Wnt/β-catenin (Wnt) target genes from being expressed in adult CNS ECs. Low Wnt activity during development modifies BBB genes epigenetically for the formation of functional BBB. As a Class-I HDAC inhibitor induces adult CNS ECs to regain Wnt activity and BBB genetic signatures that support BBB formation, our results inform strategies to promote BBB repair.
Oral supplementation of gut microbial metabolite indole-3-acetate alleviates diet-induced steatosis and inflammation in mice
Authors: Ding Yufang , Yanagi Karin , Yang Fang , Callaway Evelyn , Cheng Clint , Hensel Martha E , Menon Rani , Alaniz Robert C , Lee Kyongbum , Jayaraman Arul
Published: June 2023

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. There is growing evidence that dysbiosis of the intestinal microbiota and disruption of microbiota-host interactions contribute to the pathology of NAFLD. We previously demonstrated that gut microbiota-derived tryptophan metabolite indole-3-acetate (I3A) was decreased in both cecum and liver of high-fat diet-fed mice and attenuated the expression of inflammatory cytokines in macrophages and Tnfa and fatty acid-induced inflammatory responses in an aryl-hydrocarbon receptor (AhR)-dependent manner in hepatocytes. In this study, we investigated the effect of orally administered I3A in a mouse model of diet-induced NAFLD. Western diet (WD)-fed mice given sugar water (SW) with I3A showed dramatically decreased serum ALT, hepatic triglycerides (TG), liver steatosis, hepatocyte ballooning, lobular inflammation, and hepatic production of inflammatory cytokines, compared to WD-fed mice given only SW. Metagenomic analysis show that I3A administration did not significantly modify the intestinal microbiome, suggesting that I3A’s beneficial effects likely reflect the metabolite’s direct actions on the liver. Administration of I3A partially reversed WD-induced alterations of liver metabolome and proteome, notably, decreasing expression of several enzymes in hepatic lipogenesis and β-oxidation. Mechanistically, we also show that AMP-activated protein kinase (AMPK) mediates the anti-inflammatory effects of I3A in macrophages. The potency of I3A in alleviating liver steatosis and inflammation clearly demonstrates its potential as a therapeutic modality for preventing the progression of steatosis to non-alcoholic steatohepatitis (NASH).
Ligand bias underlies differential signaling of multiple FGFs via FGFR1
Authors: Karl Kelly , Del Piccolo Nuala , Light Taylor , Roy Tanaya , Dudeja Pooja , Ursachi Vlad-Constantin , Fafilek Bohumil , Krejci Pavel , Hristova Kalina
Published: June 2023

The differential signaling of multiple FGF ligands through a single fibroblast growth factor (FGF) receptor (FGFR) plays an important role in embryonic development. Here, we use quantitative biophysical tools to uncover the mechanism behind differences in FGFR1c signaling in response to FGF4, FGF8, and FGF9, a process which is relevant for limb bud outgrowth. We find that FGF8 preferentially induces FRS2 phosphorylation and extracellular matrix loss, while FGF4 and FGF9 preferentially induce FGFR1c phosphorylation and cell growth arrest. Thus, we demonstrate that FGF8 is a biased FGFR1c ligand, as compared to FGF4 and FGF9. Förster resonance energy transfer experiments reveal a correlation between biased signaling and the conformation of the FGFR1c transmembrane domain dimer. Our findings expand the mechanistic understanding of FGF signaling during development and bring the poorly understood concept of receptor tyrosine kinase ligand bias into the spotlight.
Somatic mutation rates scale with time not growth rate in long-lived tropical trees
Authors: Satake Akiko , Imai Ryosuke , Fujino Takeshi , Tomimoto Sou , Ohta Kayoko , Na'iem Mohammad , Indrioko Sapto , Widiyatno Widiyatno , Purnomo Susilo , Morales Almudena Molla , Nizhynska Viktoria , Tani Naoki , Suyama Yoshihisa , Sasaki Eriko , Kasahara Masahiro
Published: June 2023

The rates of appearance of new mutations play a central role in evolution. However, mutational processes in natural environments and their relationship with growth rates are largely unknown, particular in tropical ecosystems with high biodiversity. Here, we examined the somatic mutation landscapes of two tropical trees, Shorea laevis (slow-growing) and S. leprosula (fast-growing), in central Borneo, Indonesia. Using newly constructed genomes, we identified a greater number of somatic mutations in tropical trees than in temperate trees. In both species, we observed a linear increase in the number of somatic mutations with physical distance between branches. However, we found that the rate of somatic mutation accumulation per meter of growth was 3.7-fold higher in S. laevis than in S. leprosula. This difference in the somatic mutation rate was scaled with the slower growth rate of S. laevis compared to S. leprosula, resulting in a constant somatic mutation rate per year between the two species. We also found that somatic mutations are neutral within an individual, but those mutations transmitted to the next generation are subject to purifying selection. These findings suggest that somatic mutations accumulate with absolute time and older trees have a greater contribution towards generating genetic variation.
A novel traffic optimization method using GRU based deep neural network for the IoV system
Authors: Wen Wu , Xu Dongliang , Xia Yang
Published: June 2023

At present, China is moving towards the direction of “Industry 4.0”. The development of the automobile industry, especially intelligent automobiles, is in full swing, which brings great convenience to people’s life and travel. However, at the same time, urban traffic pressure is also increasingly prominent, and the situation of traffic congestion and traffic safety is not optimistic. In this context, the Internet of Vehicles (also known as “IoV”) opens up a new way to relieve urban traffic pressure. Therefore, in order to further optimize the road network traffic conditions in the IoV environment, this research focuses on the traffic flow prediction algorithm on the basis of deep learning to enhance traffic efficiency and safety. First, the study investigates the short-time traffic flow prediction by combining the characteristics of the IoV environment. To address the issues that existing algorithms cannot automatically extract data features and the model expression capability is weak, the study chooses to build a deep neural network using GRU model in deep learning for short-time traffic flow prediction, thereby improving the prediction accuracy of algorithm. Secondly, a fine-grained traffic flow statistics approach suitable for the IoV situation is suggested in accordance with the deep learning model that was built. The algorithm sends the vehicle characteristic data obtained through GRU model training into the fine-grained traffic flow statistics algorithm, so as to realize the statistics of traffic information of various types of vehicles. The advantage of this algorithm is that it can well count the traffic flow of multiple lanes, so as to better predict the current traffic status and achieve traffic optimization. Finally, the IoV environment is constructed to confirm the effectiveness of the prediction model. The prediction results prove that the new algorithm has good performance in traffic flow statistics in different scenarios.
Neutrophil extracellular trap burden correlates with the stenosis of coronary atherosclerosis
Authors: Wang Yan , Yang Mao , Xu Yuanyuan , Yan Shujun , Jin Enze , Li Xueqi
Published: June 2023

Background

Coronary atherosclerosis diseases (CADs) are associated with chronic inflammation. Neutrophil extracellular traps (NETs) are a type of novel proinflammatory cytokines whose levels are dramatically elevated in acute coronary syndrome. We conducted this study to further evaluate the association between circulating NET-associated markers and CAD in Chinese adults.

Methods

A total of 174 patients with CAD and 55 healthy controls were screened using percutaneous coronary intervention or coronary computed tomography angiography. Blood lipid levels, blood glucose levels, and blood cell counts were determined using commercial kits. Serum levels of myeloperoxidase (MPO) and neutrophil elastase (NE) were measured using ELISA. Double-stranded DNA (dsDNA) in serum was quantified using the Quant-iT PicoGreen assay. We also compared the circulating NET levels with various parameters in the study subjects.

Results

The levels of serum NET markers, dsDNA, MPO, and NE, were significantly elevated in patients with CAD, particularly in the severe group, consistent with the increase in neutrophil counts. The levels of NET markers correlated with the risk factors of AS, increasing with the number of risk factors. NET markers were identified as independent risk factors for severe coronary stenosis and also as predictors of severe CAD.

Conclusion

NETs may be related to AS and serve as indicators or predictors of stenosis in patients with severe CAD.
El tiempo invertido en la autorrevisión: ¿un indicador sobre el aprendizaje en la formación de traductores?
Authors:   Departamento de Traducción e Interpretación, Universidad de Granada. Grupo de investigación Avanti, Parra-Galiano Silvia
Published: June 2023

La autorrevisión es una parte esencial del proceso de producción de la traducción (Mossop, 2014 [2001]), en la que el traductor revisa y corrige su borrador. Puesto que las actividades vinculadas con la autorrevisión implican aplicar los conocimientos, habilidades y aptitudes de la competencia traductora (Kelly, 2002, 2005, 2008), el autocontrol del procedimiento de trabajo (Pietrzak, 2019) es fundamental para gestionar el tiempo y el esfuerzo (Gile, 2005; Pym, 2010a) que requieren, y la autorrevisión resulta un instrumento didáctico esencial para desarrollar la competencia estratégica y las creencias de autoeficacia (Haro-Soler, 2017) en la formación de traductores. En este artículo se presentan los resultados de un estudio analítico-comparativo centrado en el control del tiempo dedicado a las actividades del proceso de traducción por 20 estudiantes y la docente, con el objetivo de poner de manifiesto que el tiempo invertido en la autorrevisión es un valioso indicador sobre el progreso del aprendizaje. Los resultados del estudio muestran que los sujetos con mayor autocontrol de su procedimiento de trabajo gestionan el tiempo (y el esfuerzo) invertido en las diferentes actividades del proceso de traducción considerando sus fortalezas y debilidades al traducir (Way, 2008) y son más eficaces tanto para identificar los errores y las deficiencias de sus traducciones como para corregirlos. Finalmente, se abordan las limitaciones del estudio y otras posibilidades para analizar los datos obtenidos.
La competencia profesional docente en los Estudios de Traducción en España: propuesta provisional de un modelo de competencias
Authors:   Departamento de Traducción e Interpretación, Universidad de Granada. Grupo de investigación Avanti, Horcas-Rufián Sara
Published: June 2023

En este artículo presentamos una propuesta provisional de un modelo de competencia profesional docente (CPD) para los Estudios de Traducción (ET) en España. Para elaborar dicha propuesta, analizamos y sintetizamos la literatura sobre el estudio de la CPD en la Educación Superior en España y sobre la CPD en los ET. Nuestra propuesta de modelo de competencia profesional docente en traducción (CPDT) integra los principales aspectos presentes en la literatura con otros aspectos también relevantes que no han recibido ninguna atención, o no la suficiente, en los modelos de CPD y CPDT existentes. La descripción de los componentes de este modelo de CPDT se está utilizando en una investigación en curso como herramienta de diagnóstico para analizar el estado de desarrollo actual de la CPDT del profesorado de asignaturas de traducción en los grados en Traducción de España. Es decir, para identificar las posibles fortalezas, debilidades y carencias en la formación docente actual.
Integrating the Achilles’ heel sheet into assessing translator employability training
Authors:   Departamento de Traducción e Interpretación, Universidad de Granada. Grupo de investigación Avanti, Way Catherine
Published: June 2023

Since the Achilles’ heel sheet (AHS) was first piloted in undergraduate translation courses at the University of Granada (UGR) in the early 2000s (Way, 2003, 2008), a considerable number of years have elapsed. During this time the AHS has been modified and refined to meet the growing needs of translator trainees. This article will describe the improvements made to the AHS over the last 14 years and also describe how, after initially being used in translation modules, it has also been used in the Translation Professions module of the Foundations of Professional Translation 1 subject1 of the postgraduate Master’s Degree in Professional Translation. The introduction of the AHS in employability training has allowed us to align formative and summative assessment. By blending the use of diagnostic assessment, the AHS and the final summative assessment activity of the module, trainees are immersed in self-reflective situated learning. The activities not only guide them through an authentic first job application, but also promote self-regulated lifelong learning, critical thinking and introduce them to the importance of continuous professional development (CPD).
Mainstream Integration of Mental Health Peer Support in Canada: A Mixed Method Study
Authors: Rebeiro Gruhl Karen , Lacarte Sara , Boucher Martin
Published: June 2023

Mental health peer support was one of the key recommendations of the Mental Health Commission of Canada’s Workforce Advisory Committee (Cyr et al., 2016 [2012]) and highlighted as one way to transform the mental health system in Canada. This mixed methods study explored the work experiences of mental health peer support workers across Canada and their perceptions of integration within mainstream mental health services. The findings revealed that role confusion, stigma, lack of support to practice authentically and peer drift challenged the full integration and participation of peer support workers within Canada’s mental health system. Recommendations to mitigate these challenges are suggested.
The Bacterial Profile of Aortic Infectious Endocards: Experience of the Cardiology Department, Mohammed VI University Hospital of Marrakech, Morocco
Authors: Onguema Junior Rocyr Ibara , Zerhoudi Rim , Othende Franck Bienvenu Ekoba , Bourzeg Khaoula , Eljamili Mohammed , Karimi Saloua El , Elhattaoui Mustapha
Published: June 2023

Introduction: Infective endocarditis is defined as infection of a native or prosthetic heart valve, endocardial surface, or cardiac device. The causes and epidemiology, as well as the microbiology of the disease have evolved over the last few decades with the doubling of the average age of patients and an increased prevalence in patients with indwelling cardiac devices.
Patients and Methods: This is a retrospective study, including all subjects over 20 years of age who presented with infective endocarditis of the aortic valve, hospitalized between January 2019 and December 2022, in the Department of Cardiology and Vascular Diseases at ERRAZI Hospital-Mohammed VI University Hospital in Marrakech. Clinical, paraclinical and therapeutic data were collected for each case using an exploitation form.
Results: Over the study period, 46 patients had presented with aortic positional AR, with a sex ratio that was equal to 1.8. The mean age of the patients was 43±12.5 years. Endocarditis on aortic prosthesis was found in 15%. The valves were rheumatic in 85%. The presumed portal of entry was cutaneous in 45%, oral and ENT in 33%, urinary in 15%, and digestive in 7%. In our series, 21 out of 26 patients presented a biological inflammatory syndrome. At least one or more blood cultures were positive in 38% of cases. Coagulase-negative Staphylococcus was the most common germ in aortic infective endocarditis, found in 40% of positive blood cultures. All the patients in our series had received a combination of broad-spectrum intravenous antibiotic therapy, initially probabilistic, taking into consideration the portal of entry. Adapted after antibiogram results. The evolution during the hospitalization, was marked by an improvement of the clinical state in only 12%, a perioperative death in 38%, and a worsening of the clinical state in 50%, with an average duration of hospitalization of 14 days. In our series, 60% of the patients with positive blood cultures died, whereas there was 75% survival in the group with negative blood cultures.
Conclusion: Infective endocarditis is a serious disease because of its high morbidity and mortality. Despite improvements in diagnostic testing, antimicrobial therapy, and surgical intervention, changes in the epidemiology of IE, including the increase in healthcare-associated infections and the virulence of staphylococcus aureus as the causative organism, increase the risk of complications and death in the acute phase of IE. Action must be taken to prevent infective endocarditis, especially in this rheumatically endemic area.
Nutritional values, Nutraceutical properties, and health benefits of Arabian Date Palme fruit
Authors: AlFaris Nora Abdullah , AlTamim Jozaa Zaidan , AlMousa Lujain Abdulaziz , Albarid Najla Abdullah , AlGhamidi Fatima Ali
Published: June 2023

The date palm is widely known as a richer nutritional source and natural medical agent. Date fruit is a major source of carbohydrates and dietary fiber, and it has contains proteins, minerals, vitamins, phenolic compounds, carotenoids, sterols, and triterpenoids. The beneficial potential of this fruit is well known in Arab countries and even in the world. Date fruit has many health benefits such as Glucose-lowering potential, anti-cancer activity, antioxidant activity, hypocholesterolemia-lowering potential, antimicrobial activity, anti-inflammatory activity, bone stimulating activity, which is attributed to the existence of bioactive substances such as carotenoids, polyphenols, triterpenoids, flavonoids, sterols, and some vitamins and minerals. Overall, Arabian date palms’ nutritional values and pharmacological activities remain to be explained. Thus, this study states the history, nutritional and health effects of Arabian date palm, highlighting the possibility of palm date components developing novel beneficial approaches for managing the above mentioned illnesses.
Keywords: Arabian date palm; Arab’s tree; Nutritional values; Pharmacological activities
Analysis of The Effect of Region, Province and Breed on Somatic Cell Count in Dairy Cattle in Turkey By Regression Tree Method
Authors: Sahin Onur
Published: June 2023

This study aimed to determine the effect of various environmental factors on the somatic cell count (SCC) in cow’s milk. The material of the study consisted of an SCC analysis result obtained from 207.614 raw milk samples collected from 65.288 head cattle had different breeds, ages, lactation number, and lactation length between May and December in 2019. They were raised on 6,305 dairy farms that are members of the Cattle Breeders Association (CBAT). In order to determine the effect of region, city, and cattle breed on SCC in raw milk of cattle, a regression tree was created using the Chi-square Automatic Interaction Detection (CHAID) algorithm, a Data Mining (DM) method. Accordingly, the mean SCC value of all enterprises was determined as 201.253 cells/mL. In this study, it was found that the region, city and breed groups with the highest average somatic cell counts were CAR, MSR, MR and SAR region group (285.430 cells/mL); C09, C45, C20, C64, C48, C43 city group (266.744 cells/mL); and HF, MC, and BS breed group (295.705 cells/mL). As a result of this study, the variables affecting SCC were determined as region, city, and breed respectively, in order of importance.
Keywords: CHAID; Dairy cattle; Somatic cell count
Comparison of cotton (Gossypium hirsutum) hybrids and their non-transgenic in India
Authors: Singh Kulvir , Mishra Sudhir Kumar , Singh Manpreet , Brar Harjeet Singh , Singh Amarpreet
Published: June 2023

It is still not clear whether differential response of Bt cotton and conventional non-Bt cotton genotypes in terms of growth, phenology and yield ability are hypothetical or realistic. This study investigated the response of three Bt cotton hybrids in comparison to their conventional non-transgenic version (near-isogenic lines) along with two locally adapted genotypes for growth, yield attributes, phenological characteristics and rooting behavior. Therefore, two experiments were conducted during summer season of year 2016 and 2017 to evaluate differences among 3 popular Bt cotton hybrids along with their non-Bt version. First field experiment was conducted as a pot study wherein shoot and root parameters of 3 Bt cotton hybrids (Ankur 3028, MRC 7017, Bioseed 6588) were compared with their non-Bt version along with 2 local checks (i.e.,hirsutum cotton Cv. F2228 and arboreum cottonCv. FDK124). Second field experiment evaluated growth, phenological characteristics, yield attributes and productivity potential of above mentioned Bt and non-Bt hybrids. Findings of pot experiment could not establish any significant difference among studied Bt and non-Bt hybrids for root and shoot characteristics. However, arboreum cotton FDK124 exhibited higher root length than all genotypes. Results of second experiment revealed significant differences for phenological characteristics, wherein Bt version of all the tested hybrids exhibited earliness for flowering initiation, 50 % flowering and days to maturity over their non-Bt version. Seed cotton yield (SCY) in all hybrids possessing Bt gene was significantly higher than their non-Bt version primarily due to higher bolls plant-1. Studies conclude that introgression of Bt gene could not alter rooting parameters of evaluated cotton genotypes but significantly affected phenological stages by inducing earliness and higher SCY in Bt versions due to improved bolls plant-1.
Keywords: Bt cotton; Near-isogenic lines; Phenology; Root dry matter; Seed cotton yield
Egg weight estimation and the effect of age and plumage colors on some egg quality traits in Japanese quails (Coturnix coturnix japonica)
Authors: Arslan Emre , Güler Serdar , Çetin Orhan , Sarı M. Mücahit , Yonar Harun
Published: June 2023

The aim of this study was to investigate the effect of different age and plumage color on the egg quality traits and cholesterol levels, in addition to which traits can be used for egg weight prediction in Japanese quails. The eggs obtained from 23-week-old original plumage colored Japanese and Jumbo quails, and 39-week-old Jumbo quails; 40, 40, and 20 eggs were used respectively as the research material. The eggs obtained from 23-week-old original plumage colored Japanese and Jumbo quails, and 39-week-old Jumbo quails; 40, 40, and 20 eggs were used respectively as the research material. In terms of plumage color difference, when Japanese quails were compared to Jumbo quails; yolk weight, yolk height, yolk diameter were higher, and likewise the cholesterol level was lower (P<0.01). The lowest cholesterol content was found in eggs from 23-week-old Japanese quail (P<0.01). Egg width, shape index, yolk height, and shell weight in group 1; albumen weight, yolk diameter, and egg volume in group 2; egg volume and egg length data in group 3 have determined the best fit for estimation of the egg weight. As a result, the plumage color is a factor that affected the egg quality traits and cholesterol level in quails. Furthermore, some egg quality traits may be used to establish the equations for estimation of the egg weight.
Keywords: Age; Egg quality traits; Egg weight estimation; Plumage color; Quail