bluuebunny/crossref_metadata_2025 huggingface dataset:
Representação do conhecimento por meio de knowledge graph: aplicação e categorização no domínio educacional
Authors: Barcelos Bartholomeo Oliveira , Duda Robson Fernando , Da Silva Adão Daniel , Gonçalves Alexandre Leopoldo , Todesco José Leomar
Published: March 2023

Este estudo tem como objetivo investigar quais são as aplicações de Knowledge Graph (KG) no domínio educacional, bem como identificar as características dos KGs gerados nas soluções de ensino aos quais foram aplicados. Como procedimentos metodológicos utilizou-se uma revisão narrativa, com busca estruturada, que analisou três bases de pesquisa: Scopus, Web of Science e IEEE Xplore. Ao todo foram identificadas 71 publicações, que após serem submetidas a critérios de inclusão e exclusão alcançaram um quantitativo de 29 pesquisas elegíveis para análise em profundidade. Como resultados, foram propostas duas categorizações, a primeira colabora para a análise e identificação das etapas de construção e implementação de uma arquitetura básica de KG. Já a segunda, combina as finalidades e objetivos dos KGs evidenciando as características e aplicações destes no contexto de ensino.
THE RELATION OF NEUTROPHIL/LYMPHOCYTE RATIO, PLATELET/LYMPHOCYTE RATIO AND MEAN PLATELET VOLUME WITH IDIOPATHIC ACUTE ANTERIOR UVEITIS
Authors: Demir Ulku
Published: March 2023

ABSTRACT Purpose: In this study, leukocyte, lymphocyte, neutrophil,
platelet count, mean platelet volume (MPV), neutrophil/lymphocyte (NLR)
ratio and platelet/lymphocyte ratio (PLR) were retrospectively evaluated
in patients with idiopathic acute anterior uveitis. Methods: Medical
records were retrospectively reviewed from March 2016 to February 2020.
50 patients, 25 men and 25 women, and 50 healthy volunteers, 25 males
and 25 females, as the control group were included in the study. Blood
samples of the patients were taken before starting treatment. A complete
ophthalmological examination including corrected visual acuity,
tonometry, slit lamp and fundus examination was performed in all
patients. Gender, age, leukocyte, neutrophil, lymphocyte, platelet, MPV,
PLR, NLR values of the patients were recorded. Results: In this study, a
statistically significant difference was found in the values of
leukocyte (p<0.001), neutrophil (p<0.001), platelet
(p<0.001), NLR (p<0.001) and PLR
(p<0.001). There was no significant difference between the two
groups in terms of the number of lymphocyte (p=0.063) and value of MPV
(p=0.051). Leukocyte, neutrophil, platelet count, NLR, PLR values were
found to be higher in the uveitis group compared to the control group.
Conclusions: In this retrospective study, it is thought that leukocyte,
neutrophil, platelet count, PLR, NLR, levels are significant in patients
with idiopathic acute anterior uveitis and can be used in early
diagnosis.
ON THE LAGRANGIAN STRUCTURE OF VLASOV-MAXWELL EQUATIONS FOR ELECTROMAGNETIC FIELD WITH BOUNDED VARIATION
Authors: Borrin Henrique
Published: March 2023

We study the Lagrangian structure of Vlasov-Maxwell equations. We show
that for sufficiently regular initial conditions, renormalized solutions
of these systems are Lagrangian and that these notions of solution, in
fact, coincide. As a consequence, finite-energy solutions are shown to
be transported by a global flow. These results extend to our setting
those obtained by Ambrosio, Colombo, and Figalli [3] for the
Vlasov-Poisson system and by the first author and Marcon for
relativistic Vlasov systems [5]; here, we analyze the
electromagnetic fields with bounded variation under Maxwell equations.
Stone removal in a five-year-old child with extrahepatic biliary obstruction using ERCP: A case report and a mini-review
Authors: Niknam Ramin , Mortazavi Seyede Maryam Mahdavi , Jahromi Mehdi Ghaderian , Davoodi Marzieh , Soheili Marzieh , Ataollahi Maryam , Moshfeghinia Reza
Published: March 2023

We describe a 5-year-old child with extrahepatic biliary stone who
successfully underwent endoscopic retrograde cholangiopancreatography
for stone removal. He suffered from persistent colicky abdominal pain
accompanied by fever that biliary stone confirmed him. ERCP along with
other methods, can be considered a safe procedure for managing BD in
children.
Convalescent plasma therapy in immunocompromised patients infected with the BA.1 or BA.2 Omicron SARS-CoV-2
Authors: Richier Quentin , Minardiere Benjamin De Valence De , Chopin Dorothée , Gras Emmanuelle , Levi Laura , Aad Yasmine Abi , Pacanowski Jérôme , Meynard Jean-Luc , Plaçais Léo , Fey Dorothée , Couture Priscille , Martin-Blondel Guillaume , Pestre Vincent , Woessner Juliette , Ancellin Sophie , Weyrich Pierre , Carpentier Benjamin , Idri Salim , Tiberghien Pierre , Surgers Laure , Hueso Thomas , Lacombe Karine
Published: March 2023

The emergence of SARS-CoV-2 Omicron variant has led to a complete
reconfiguration of the therapeutic landscape, with most monoclonal
antibodies having lost any neutralization activity. We report here a
case series of 75 immunocompromised patients infected by the Omicron
variant who benefited of convalescent plasma. At baseline, 49 (68%) of
the participants had a WHO score of 5 and 23 (32%) a WHO score of 6. At
day 28 the case fatality was 24%. We observed no significant difference
in the clinical outcome between patients with hematological
malignancies, solid organ transplantation or auto-immune diseases. These
promising results require controlled studies.
Oral morphine induces spinal 5-hydroxytryptamine (5-HT) release using an opioid receptor-independent mechanism.
Authors: Nakamura Shingo , Komatsu Shuji , Yamada Toshihiko , YAMAMOTO TATSUO
Published: March 2023

Background and Purpose Morphine induces spinal 5-hydroxytryptamine
(5-HT) release, but the role and mechanism of this release is unclear.
The purpose of this study was to define the role and mechanism of spinal
5-HT release induced by oral morphine. We also examined whether
persistent pain affected the oral morphine-induced spinal release of
5-HT. Experimental Approach Spinal 5-HT release was measured using
microdialysis in lumbar cerebrospinal fluid (CSF). Two opioids, morphine
and oxycodone, were orally administered and 5-HT release was measured in
awake rats. Naloxone was used to determine whether the effect of
morphine on 5-HT release was mediated by opioid receptor activation. To
study persistent pain, the formalin test was used. Forty-five minutes
after oral morphine, the formalin test was started and spinal 5-HT
release was measured. Key Results Oral morphine, but not oral oxycodone,
increased 5-HT release in the spinal cord to approximately 4,000% of
the baseline value, and this effect of morphine was not antagonised by
naloxone at the dose that antagonised the analgesic effect of morphine.
Formalin-induced persistent pain itself had no effect on spinal 5-HT
release but enhanced the oral morphine-induced spinal 5-HT release.
Conclusion and Implications Oral morphine-induced spinal 5-HT release is
not mediated by opioid receptor activation. Spinal 5-HT release induced
by oral morphine does not play an important role in the analgesic effect
of morphine. Persistent pain increases oral morphine-induced spinal 5-HT
release.
Three-Dimensional Kinematics-Based Real-Time Localization Method Using Two Robots
Authors: Zarrouk David , Elmakis Guy
Published: March 2023

This paper presents a precise two-robot collaboration method for
3D self-localization relying on a single rotating camera and onboard
accelerometers used to measure the tilt of the robots. This method
allows for localization in GPS-denied environments and in the presence
of magnetic interference
or relatively (or totally) dark and
unstructured unmarked locations. One robot moves forward on each step
while the other remains stationary. The tilt angles of the robots
obtained from the accelerometers and the rotational angle of the turret,
associated with the video analysis, make it possible to continuously
calculate the location of each robot. We describe a hardware setup used
for experiments and provide a detailed description of the algorithm that
fuses the data obtained by the accelerometers and cameras and runs in
real-time on onboard micro-computers. Finally, we present 2D and 3D
experimental results, which show that the system achieves 2% accuracy
for the total travelled distance.
Subacute sensory neuropathy as a Paraneoplastic syndrome associated with an undifferentiated Lung carcinoma A case report
Authors: lajnef Ines , ksontini feryel , Saied Zakaria , Zenzri Yosr , chaabouni mohamed , ayadi mouna , raies henda
Published: March 2023

This report describes a case of anti-hu antibody associated
paraneoplastic sensory neuropathy with an undifferentiated lung tumor .
The aim of this case was to highlight the importance of a
multidisciplinary team approach for early recognition and rapid
treatment of paraneoplastic neurological syndromes
Lessons from Robot-Assisted Disaster Response Deployments by the German Rescue Robotics Center Task Force
Authors: Surmann Hartmut , Kruijff-Korbayová Ivana , Daun Kevin , Schnaubelt Marius , Stryk Oskar von , Patchou Manuel , BÃűcker Stefan , Wietfeld Christian , Quenzel Jan , Schleich Daniel , Behnke Sven , Grafe Robert , Heidemann Nils , Slomma Dominik
Published: March 2023

Earthquakes, fire, and floods often cause structural collapses
of buildings. The inspection of damaged buildings poses a high risk for
emergency forces or is even impossible, though. We present three recent
selected missions of the Robotics Task Force of the German Rescue
Robotics Center, where both ground and aerial robots were used to
explore destroyed buildings. We describe and reflect the missions as
well as the lessons learned that have resulted from them. In order to
make robots from research laboratories fit for real operations,
realistic test environments were set up for outdoor and indoor use and
tested in regular exercises by researchers and emergency forces. Based
on this experience, the robots and their control software were
significantly improved. Furthermore, top teams of researchers and first
responders were formed, each with realistic assessments of the
operational and practical suitability of robotic systems.
Design and FPGA Implementation of pre-computation based radix-4 hyperbolic CORDIC for Direct Digital Synthesis
Authors: Pujari Shubhanjay S. , Manickam Bhaskar
Published: March 2023

This paper presents the hardware and delay efficient design of a
radix-4 pipelined hyperbolic Coordinate Rotation Digital Computer
(CORDIC) architecture. The proposed design uses pre-computation based
micro-rotation sequence generation to reduce the cycle time and number
of iterations. It also eliminates the need for residue angle computation
in every iteration that helps to enhance the operating speed. The
methodology finds a linear relation between rotation angle input and
micro-rotation sequence by selectively choosing elementary angles from
the set of valid angles. Therefore, it requires six clock cycles to
compute the hyperbolic functions (cosh/sinh). Further, the
region of convergence (ROC) of the proposed design is extended to cover
the entire coordinate space. Based on the proposed hyperbolic CORDIC
design, a hyperbolic (Direct Digital Synthesis) DDS is implemented using
XC7VX330T (Vertex-7 family) field-programmable gate array (FPGA) in
Xilinx ISE 14.4 platform. The proposed design achieves 47% and 37%
savings in basic logic elements and number of slices respectively than
recent designs. The design also achieves an improved slice delay product
of 5.28 anda maximum frequency of operation of 500.75MHz.
Gene Therapy Using Plasmid DNA Encoding Bone Morphogenetic Protein 2 and Vascular Endothelial Growth Factor 164 Genes for the Treatment of Equine Proximal Suspensory Desmitis: Case Reports
Authors: Kovac Milomir , Aliev Ruslan , Berestov Iliya Berestov , Aimaletdinov Alexander , Rutland Catrin , Rizvanov Albert , Zakirova Elena
Published: March 2023

Injury to the proximal part of the equine suspensory ligament (SL),
called proximal suspensory desmitis (PSD), commonly causes lameness in
horses. PSD is extremely difficult to manage and treat, with present
methods often unable to achieve full recovery, especially in chronic
cases. The present study was the first to use gene therapy to restore
moderate and severe injuries of the proximal suspensory ligament in
horses. Plasmid DNA encoding species specific bone morphogenetic protein
2 (BMP2) and vascular endothelial growth factor (VEGF164) was injected
into the site of proximal suspensory ligament injury, followed by box
rest and a controlled exercise program. Clinical observations and
ultrasound imaging was used to evaluate effectiveness over a period of
12 months. No negative side effects were observed. Clinical improvements
were observed, especially in the forelimb affected horses, by day 30. In
horses with chronic hindlimb PSD few clinical improvements were
reported. Echogenicity and the fiber alignment scoring improved but no
concomitant changes to cross section area, dorsopalmar thickness or
lateromedial width of the proximal suspensory ligament were observed.
The transfer of BMP2 and VEGF164 genes into the equine PSL exhibited
beneficial effects in horses with acute or subacute forms of lesions,
primarily in the forelimb.
Determinants of Farmers' Willingness for Land Consolidation in Khyber Pakhtunkhwa, Pakistan
Authors: QASIM SAID , Qasim Muhammad , Hassan Anees
Published: March 2023

Land fragmentation is one of the main hurdles that restricts farmers
from technology use for enhancing agricultural production especially in
developing countries. The farmers are even now at threat of further
fragmentation of their lands in the future due to sharing system of
lands among the heirs. This research, attempted to find out determinants
of small holding farmers’ willingness for land consolidation in Khyber
Pakhtunkhwa (KPK) province of Pakistan. The primary data was collected
through semi-structured questionnaire from randomly selected 200 farmers
from Charsadda, Sawabi and Nowshera districts of (KPK) Province .
Chi-square test and Binary logistic regression model were used to
identify determinants of farmers’ willingness for land consolidation.
Farmers’ reported main reasons in favor of willingness were benefit of
compact land than scattered parcels, increased production, better
management of land and ease of transporting inputs. Conversely, reasons
against willingness for mutual swapping included farmers’ sentimental
attachments to their lands, lack of proper compensation mechanism,
differences in value of land and renting-out land parcels. Among
determinants of willingness included distance of land parcel, land
holding size, number of land parcels, irrigated land area and
participation in agriculture related trainings. The study suggests
arrangement of seminars and workshops for farmers in their own rural
settings for awareness regarding land consolidation, a better
compensation mechanism to come up on mutual exchange of land parcels
with uneven prices and land parcels of different irrigation methods.
Genome resequencing reveals population divergence and local adaptation of blacklegged ticks in the United States
Authors: Schoville Sean , Burke Russell , Dong Dahn-young , Ginsberg Howard , Maestas Lauren , Paskewitz Susan , Tsao Jean
Published: March 2023

Tick vectors and tick-borne disease are increasingly impacting human
populations globally. An important challenge is to understand tick
movement patterns, as this information can be used to improve management
and predictive modeling of tick population dynamics. Evolutionary
analysis of genetic divergence, gene flow, and local adaptation provides
insight on movement patterns at large spatiotemporal scales. We develop
low coverage, whole genome resequencing data for 92 samples representing
range-wide variation in blacklegged ticks, Ixodes scapularis,
across the U.S. Through analysis of population genomic data, we find
that tick populations are structured geographically, with gradual
isolation by distance separating three population clusters in the
northern U.S., southeastern U.S., and a unique cluster represented by a
sample from Tennessee. Populations in the northern U.S. underwent
population contractions during the last glacial period and diverged from
southern populations at least 50 thousand years ago. Genome scans of
selection provide strong evidence of local adaptation at genes
responding to host defenses, blood-feeding, and environmental variation.
In addition, we explore the potential of low coverage genome sequencing
of whole-tick samples for documenting the diversity of microbial
pathogens. Metagenomic analyses recover important tick-borne pathogens
and their geographical variation, including the higher prevalence of
Borrelia burgdorferi in northern populations, geographic strain
variation in Rickettsia species, and the rare occurrence of
B. miyamotoi and Anaplasma phagocytophilum. The
combination of restricted pathogen distribution, isolation by distance,
and local adaptation in blacklegged ticks demonstrates that gene flow,
including recent expansion, is limited to geographical scales of a few
hundred kilometers.
3D reconstruction of surface roughness of eroding leading edge of wind turbine blades
Authors: Tempelis Antonios , Mishnaevsky L.
Published: March 2023

In this paper, 3D reconstruction of the leading edge of wind turbine
blades from images, also known as photogrammetry, is investigated. The
technique was applied to a decommissioned blade with an eroded leading
edge, with images captured by a smartphone. The reconstructed 3D surface
was accurate, when compared to the captured images, despite the small
number of images used. A solid model was then created and imported into
a finite element modelling software for rain-droplet impact simulations.
Photogrammetry is relatively cheap, when compared to other surface
scanning techniques, and provides means of monitoring erosion damage
when combined with drone imaging. Further investigations of the
parameters which control the accuracy of the reconstructed surface must
be performed, to fully explore the potential of photogrammetry for 3D
reconstruction of leading edge erosion damage.
Robust Siamese Tracking with Asymmetrical Feature Processing Network
Authors: Mao Zhongjie , Chen Xi , Yan Jia , Fan Shenghua
Published: March 2023

The Siamese tracker consists of two components: a classification and a
regression networks. Despite their different roles, most Siamese
trackers have similar feature fusion modules in the two networks,
leading to the neglect of their unique characteristics. In this work, we
experimentally discover that the two networks place different levels of
emphasis on different types of information. Specifically, regression
tends to rely on semantic information, while classification places more
emphasis on global information. Therefore, we propose a new tracking
structure named SGTrack, which includes a semantic augmentation fusion
(SAF) for regression and a global relevance fusion (GRF) for
classification. It allows us to unlock the full potential of both
networks. The experimental results of our method on five benchmarks
provide evidence of a notable improvement in tracking performance, while
preserving real-time speed.
Assessing Impacts of Future Land Cover and Rainfall Change on Urban Flooding Using An Event-based Resilience Index
Authors: Li Jiada , Burian Steven , Strong Court
Published: March 2023

Assessing the resilience of urban drainage systems requires the
consideration of future threats that will disrupt the system performance
and trigger urban flooding failures. However, most existing resilience
assessments of urban drainage systems rarely consider the uncertainties
from future urban redevelopment and climate change, which leads to the
underestimation of future disturbances toward system performance. This
paper fills in the gap of assessing the combined and relative impacts of
future impervious land cover and rainfall changes on flooding resilience
in the context of a densely-infilled urban catchment severed by an urban
drainage system in Salt Lake City, Utah, the USA. An event-based
flooding resilience index is proposed to measure climatic and urbanized
impacts on flooding resilience from system-level to junction-level,
enabling engineers to harvests high-resolution infrastructure adaptation
strategies at the vulnerable spots. Impact comparison shows that
imperious urban surface induces more effects on the system performance
curves by magnifying the maximum failure level, lengthening the recovery
duration, and aggravating the flooding severity than future rainfall
changes. A nonlinear logarithm resilience correlation is found, and this
finding shows that flooding resilience is more sensitive to the land
imperviousness change due to urban redevelopment than rainfall intensity
change in the case study. This research work predicts the system
response to the uncertainties induced by climate change and urban
redevelopment, improving the understanding of impacts analysis and
contributing to the advancement of resilient urban drainage systems in
changing environments.
“Show me how to use a microscope” - The development and evaluation of certification as direct assessment of practical lab skills
Authors: Eidesen Pernille , Bjune Anne , Lang Simone
Published: March 2023

Practical lab skills are rarely directly assessed. To improve
constructive alignment between described learning outcomes of practical
skills and assessment, we developed and tested a certification procedure
for microscopy skills. The procedure was embedded into the ordinary
learning activity, so no additional time was needed. Three slightly
different protocols were developed within the framework of sociocultural
learning theory and built like a skill ladder including direct peer
assessment and elements of gamified learning. The protocols varied
slightly in the way students were prepared for the certification, the
number of steps/levels of achievement, and the consequences of failing.
We tested the protocols at three different academic institutions and
within 11 courses of varying sizes and academic levels in biology or
geology. Feedback were collected through online surveys (n = 207) or
orally after sessions. One protocol provided instruction videos as
preparation material. Instruction videos provided increased
understanding of the task, but tactile training was most important for
learning. Regardless of institution, type of preparation, and level of
former experience, the certification procedure made students clearly
more engaged in the exercise. The majority reported that the
certification procedure increased their motivation to learn, increased
their learning outcome, and was appropriate for assessing practical
skills. Students with no or little experience in microscopy before the
exercise were more positive about the certification procedure compared
to skilled students, and the level of engagement and preparation was
higher when there were some consequences of failing. Most students felt
comfortable being certified by peers, but some students expressed
concern about peers making mistakes. The presented certification
procedure can easily be adapted to assess other practical skills, and
with some adjustments be an efficient method for assessment-as-learning,
merging formative- and summative assessment.
Effect of lawsone preconditioned mesenchymal stem cells on the regeneration of pancreatic beta cells in type 1 diabetic rats
Authors: Masnoon Javeria , Ishaque Aisha , Khan Irfan , Salim Asmat , Kabir Nurul
Published: March 2023

Background: Diabetes is one of the major health issues globally. T1DM
develops due to the destruction of pancreatic beta cells. Mesenchymal
stem cells having remarkable self-renewal and differentiation potential,
can regenerate beta cells. MSCs preconditioned with bioactive small
molecules possess enhanced biological features and therapeutic potential
under in vivo environment. Interestingly, compounds of naphthoquinone
class possess anti-diabetic, anti-inflammatory properties, and can be
explored as potential candidates for preconditioning MSCs. Aim: This
study analyzed the effect of lawsone preconditioned human umbilical cord
MSCs (hUMSCs) on the regeneration of β-cells in the STZ-induced type 1
diabetic rats. Methods: hUMSCs were isolated and characterized for the
presence of surface markers. MSCs were preconditioned with optimized
concentration of lawsone. T1D rat model was established by injecting 50
mg/kg of streptozotocin intraperitoneally. Untreated and lawsone
preconditioned MSCs were transplanted into the diabetic rats via tail
vein. Fasting blood sugar and body weight were monitored regularly for 4
weeks. Pancreas was harvested and beta cell regeneration was evaluated
by H&E staining and gene expression analysis. Immunohistochemistry was
also done to assess the insulin protein expression. Results: Lawsone
preconditioned MSCs showed better anti-hyperglycemic effect, compared to
untreated MSCs. Histological analysis presented the regeneration of
islets of Langerhans with higher expression of β-cell genes and reduced
expression of inflammatory markers. Immunohistochemistry revealed
intense insulin expression in the preconditioned compared to the
untreated MSCs. Conclusion: It is concluded from the present study that
lawsone preconditioned MSCs were able to exhibit pronounced
anti-hyperglycemic effect in vivo compared to MSCs alone.
Pore-scale imaging of multiphase flow fluctuations in core-scale samples
Authors: Wang Shan , Spurin Catherine , Bultreys Tom
Published: March 2023

Representative elementary volumes (REVs) are an important concept in
studying subsurface multiphase flow at the continuum scale. However,
fluctuations in multiphase flow are currently not represented in
continuum scale models, and their impact at the REV-scale is unknown.
Previous pore-scale imaging studies on these fluctuations were limited
to small samples with mm-scale diameters and volumes on the order of
~ 0.5 cm3. Here, we image steady-state co-injection
experiments on a one-inch diameter core plug sample, with nearly two
orders of magnitude larger volume (21 cm3), while maintaining a
pore-scale resolution with X-ray micro-computed tomography. This was
done for three total flow rates in a series of drainage fractional flow
steps. Our observations differ markedly from those reported for mm-scale
samples in two ways: the macroscopic fluid distribution was less
ramified at low capillary numbers (Ca) of 10-7; and the volume fraction
of intermittency initially increased with increasing Ca (similar to
mm-scale observations), but then decreased at Ca of 10-7. Our results
suggest that viscous forces may play a role in the cm-scale fluid
distribution, even at such low Ca, dampening intermittent pathway flow.
A REV study of the fluid saturation showed that this may be missed in
smaller-scale samples. Pressure drop measurements suggest that the
observed pore-scale fluctuations resulted in non-Darcy like upscaled
behavior. Overall, we show the importance of large field-of-view
high-resolution imaging to bridge the gap between pore- and
continuum-scale multiphase flow studies, in particular of pore-scale
fluctuations.
Predicting PM2.5 Concentrations Across USA Using Machine Learning
Authors: Vignesh P. Preetham , Jiang Jonathan H , Kishore Pangaluru
Published: March 2023

Fine particulate matter with a size less than 2.5 µm (PM2.5) is
increasing due to economic growth, air pollution, and forest fires in
some states in the United States. Although previous studies have
attempted to retrieve the spatial and temporal behavior of PM2.5 using
aerosol remote sensing and geostatistical estimation methods the coarse
resolution and accuracy limit these methods. In this paper the
performance of machine learning models on predicting PM2.5 is assessed
with Linear Regression (LR), Decision Tree (DT), Gradient Boosting
Regression (GBR), AdaBoost Regression (ABR), XG Boost (XGB), k-nearest
neighbors (KNN), Long Short-Term Memory (LSTM), Random Forest (RF), and
support vector machine (SVM) using PM2.5 station data from 2017-2021. To
compare the accuracy of all the nine machine learning models the
coefficient of determination (R2), root mean square error (RMSE),
Nash-Sutcliffe efficiency (NSE), root mean square error ratio (RSR), and
percent bias (PBIAS) were evaluated. Among all nine models the RF and
SVM models were the best for predicting PM2.5 concentrations. Comparison
of the PM2.5 performance metrics displayed that the models had better
predictive behavior in the western United States than that in the
eastern United States.
Modulation of Tropical Convection-circulation Interaction by Aerosol Indirect Effects in a Global Convection-permitting Model
Authors: Su Chun-Yian , Wu Chien-Ming , Chen Wei-Ting , peters john
Published: March 2023

Observations suggest tropical convection intensifies when aerosol
concentrations enhance, but quantitative estimations of this effect
remain highly uncertain. Leading theories for explaining the
intensification are based on the dynamical response of convection to
changes in cloud microphysics independently from possible changes in the
environment. Here, we provide a new perspective on aerosol indirect
effects on tropical convection by using a global convection-permitting
model that realistically simulates convection-circulation interaction.
Simulations of radiative-convective equilibrium show that pollution
facilitates the development of deep convection in a drier environment,
but cloud condensates are more likely to be exported from moist clusters
to dry areas, impeding the large-scale moisture-convection feedback and
limiting the intensity of maximum precipitation (30 vs. 47 mm
h\textsuperscript{-1}). Our results emphasize the
importance of allowing atmospheric phenomena to evolve continuously
across spatial and temporal scales in simulations when investigating the
response of tropical convection to changes in cloud microphysics.
Enhancing Estimation Accuracy of Nonstationary Hydrogeological Fields via Geodesic Kernel-based Gaussian Process Regression
Authors: Park Eungyu
Published: March 2023

In this study, the combined application of geodesic kernel and Gaussian
process regression was investigated to estimate nonstationary hydraulic
conductivity fields in two-dimensional hydrogeological systems.
Particularly, a semi-analytical form of the geodesic distance based on
the intrinsic geometry of the manifold was derived and used to define
positive definite geodesic covariance matrices that are employed for
Gaussian process regression. Furthermore, the proposed approach was
applied to a series of synthetic hydraulic conductivity estimation
problems and the results show that the incorporation of secondary
information, such as geophysical or geological interpretations, can
considerably improve the estimation accuracy, especially in
nonstationary fields. Moreover, groundwater flow and solute transport
simulations based on the estimated hydraulic conductivity fields
revealed that the accuracy of the simulations was strongly affected by
the inclusion of secondary information. These results suggest that
incorporating secondary information into manifold geometry can
remarkably improve the estimation accuracy and provide new insights on
the underlying structure of geological data. This proposed approach has
crucial implications for hydrogeological applications, such as
groundwater resource management, safety assessments, and risk management
strategies related to groundwater contamination.
Transient deformation excited by the 2021 M7.4 Maduo (China) earthquake: Evidence of a deep shear zone
Authors: Jin Zeyu , Fialko Yuri , Yang Hongfeng , Li Yu
Published: March 2023

The 2021 M7.4 Maduo (China) earthquake ruptured a 170 km-long
left-lateral fault within the Bayan Har tectonic block in the northeast
Tibetan Plateau. We use Sentinel-1 and ALOS-2 Interferometric Synthetic
Aperture Radar, and Global Navigation Satellite System data to
investigate the mechanisms of coseismic and postseismic deformation due
to the Maduo earthquake. We present a refined coseismic slip model that
features variations in both strike and dip angles, constrained by the
rupture trace and precisely located aftershocks. The postseismic
displacements are discontinuous along the fault trace, indicating
shallow afterslip and velocity-strengthening friction in the top 2-3 km
of the upper crust. Postseismic displacements that have the same sense
as the coseismic ones are also observed at larger (> 50 km)
distances away from the fault trace. The observed surface deformation is
qualitatively consistent with either deep afterslip or viscoelastic
relaxation, but does not exhibit obvious features that could be
attributed to poroelastic effects. We developed a fully coupled model
that accounts for both stress-driven creep on a deep localized shear
zone and viscoelastic relaxation in the bulk of the lower crust. The
mid- to near-field data can be reasonably well explained by either deep
afterslip or non-Maxwellian visco-elasticity. However, a good fit to
both the near and far-field (> 150 km) GNSS data cannot be
achieved assuming the bulk viscoelastic relaxation alone, and requires a
contribution of deep afterlip and/or a localized shear zone extending
through much of the lower crust.
Mesoscale convective systems modulated by convectively coupled equatorial waves
Authors: Cheng Yuan-Ming , Dias Juliana , Kiladis George , Feng Zhe , Leung L. Ruby
Published: March 2023

Mesoscale convective systems (MCSs) produce over 50% of tropical
precipitation and account for the majority of extreme rainfall and
flooding events. MCSs are considered the building blocks of larger-scale
convectively coupled equatorial waves (CCEWs). While CCEWs can provide
favorable environments for convection, how CCEWs can systematically
impact organized convection and thereby MCS characteristics is less
clear. We examine this question by analyzing a global MCS tracking
dataset. During the active phase of CCEWs, MCS frequency increases and
MCSs rain harder, produce more lifetime total rain, and grow larger in
size. The probability of extreme MCSs also elevates. These changes are
most pronounced when MCSs are associated with Kelvin waves and tropical
depression-type waves while least so with the Madden-Julian Oscillation.
These results can be benchmarks to improve model representation of MCS
interactions with large-scale circulations and can be leveraged
operationally for extended forecasts of high-impact MCSs.
Salt-penetrating and non-salt-penetrating tear faults in central Tarim Basin
Authors: bian qing , Wang Zhendong
Published: March 2023

We examined two tear faults, namely, Nos. 4 and 7 Faults, in Tarim Basin
to investigate how a tear fault penetrates the salt layer. Using
high-quality seismic data, we showed that No. 4 Fault penetrates the
salt layer, whereas No. 7 Fault does not. We calculated the strata
shortening data of Nos. 4 and 7 Faults. For No. 4 Fault, we observed
shortening differences between the western and eastern sections in both
the supra- and sub-salt strata, whereas for No. 7 Fault, we observed
shortening differences only in the supra-salt strata. We demonstrated
that under the action of thrusting, a tear fault could penetrate the
salt layer if there is a shortening difference in the different
positions of the sub-salt strata. A lack of shortening difference in the
sub-salt strata implies that a tear fault cannot penetrate the salt
layer, even though the sub-salt strata are deformed during thrusting.
A case study of computer science lecturer’s selection and use of digital tools in an Irish Technological University
Authors: Gleeson Michael
Published: March 2023

This research explores factors that influence the selection and use of digital tools as part of computer science lecturer’s professional practice. The research takes the form of an intrinsic case study and as such the intent is to better understand and identify the uniqueness of the case by focusing on computer science lecturers professional practice. The author draws upon activity theory as its theoretical framework to expose explanatory and contextual insight, whilst not attempting to provide a complete overview of the domain. The primary data was gathered through semi-structured interviews with five computer science lecturers. It is evident from the literature that among others, user experience and compatibility with teaching pedagogy should be factors to be considered when selecting digital tools and this study offers confirmation these. Furthermore, literature suggests that the overuse of too many digital tools or ‘digital tool sprawl’ is an emerging issue in higher education. This corresponds with a significant finding from this study, which reveals an unintended consequence of computer science lecturer’s digital agency, typically characterized as ‘positive’, can, as part of professional practice, actually exacerbate the issue of ‘digital tool sprawl’ in higher education.
Division problem of the perturbed form of order one of the Chebyshev form of second kind
Authors: Ben Hadj , Mejri M.
Published: March 2023

We study the regularity of the form ( linear functional) satisfying the
functional equation (x2 ? c2)u = ?v where c ? C, ? ? C ? {0} and v is the
perturbed form of order one of the Chebyshev form of second kind. The
integral representation of the form u is highlighted. Moreover, some
symmetric second degree forms of class two and four are given.
Fractional Hermite-Hadamard type inequalities for subadditive functions
Authors: Ali Muhammad , Sarikaya Mehmet , Budak Hüseyin
Published: March 2023

In this paper, we establish different variants of fractional Hermite-Hadamard
inequalities for subadditive functions via Riemann-Liouville fractional
integrals. Moreover, we offer some fractional integral inequalities for the
product of two subadditive functions via Riemann-Liouville fractional
integrals. It is also shown that the inequalities offered in this research
are the generalization of the already given inequalities for convex
functions and subadditive functions.
On GCED matrices over UFDs
Authors: Zeid W. , Chehade H. , Rasheed F.
Published: March 2023

An extension of the GCED matrices from the domain of natural integers to the unique factorization domain is given. The structure of these type of matrices defined on both arbitrary sets and GCED-closed sets are presented. Moreover, we present exact expressions for the determinant and the inverse of such matrices. The domains of Gaussian integers and polynomials over finite fields are used to illustrate the work.
Initiation of iGlarLixi Versus Basal-Bolus Insulin in Adults With Type 2 Diabetes Advancing From Basal Insulin Therapy: The SoliComplex Real-World Study
Authors: Pantalone Kevin M. , Heller Caroline , Lajara Rosemarie , Lew Elisheva , Li Xuan , Dex Terry , Kilpatrick C. Rachel
Published: March 2023

Background

When type 2 diabetes is suboptimally controlled with basal insulin, prandial insulin injections are commonly added (i.e., a basal-bolus insulin regimen), which can increase treatment burden and hypoglycemia risk. The once-daily injectable iGlarLixi is an alternative treatment.

Methods

This retrospective analysis of the U.S. Optum Clinformatics database compared outcomes in adults (≥18 years of age) with type 2 diabetes who previously received basal insulin and were newly initiated on iGlarLixi or basal-bolus insulin therapy. Cohorts were propensity score–matched in a 1:1 ratio on baseline characteristics, and imbalances were adjusted in multivariate analyses. Subgroup analyses were performed for people ≥65 years of age and those with a baseline A1C ≥9%. The primary end point was persistence with therapy at 12 months in the overall population. Secondary end points were treatment adherence, health care resource utilization (HCRU), costs, any hypoglycemia, and A1C change at 12 months.

Results

Cohorts each comprised 1,070 participants. Treatment persistence at 12 months was statistically significantly higher for iGlarLixi versus basal-bolus insulin therapy (43.7 vs. 22.3%, hazard ratio 0.51, 95% CI 0.46–0.57, adjusted P <0.001). Adherence was numerically higher for iGlarLixi, and hypoglycemia events, HCRU, and costs were numerically lower for iGlarLixi. A1C reduction from baseline was slightly greater for basal-bolus insulin. Results for both subgroups (≥65 years of age and baseline A1C ≥9%) were similar to those of the overall population.

Conclusion

In this observational study, initiation of once-daily iGlarLixi versus basal-bolus insulin was associated with higher persistence, lower hypoglycemia, and similar A1C reduction without increasing HCRU or costs regardless of age or A1C. iGlarLixi could be an alternative to basal-bolus insulin, particularly for older adults with type 2 diabetes who require treatment simplification with lower hypoglycemia risk.
Initiation of iGlarLixi Versus Basal-Bolus Insulin in Adults With Type 2 Diabetes Advancing From Basal Insulin Therapy: The SoliComplex Real-World Study
Authors: Pantalone Kevin M. , Heller Caroline , Lajara Rosemarie , Lew Elisheva , Li Xuan , Dex Terry , Kilpatrick C. Rachel
Published: March 2023

  

Background. When type 2 diabetes is suboptimally controlled with basal insulin, prandial insulin injections are commonly added (i.e., a basal-bolus insulin regimen), which can increase treatment burden and hypoglycemia risk. The once-daily injectable iGlarLixi is an alternative treatment. 

Methods. This retrospective analysis of the U.S. Optum Clinformatics database compared outcomes in adults (≥18 years of age) with type 2 diabetes who previously received basal insulin and were newly initiated on iGlarLixi or basal-bolus insulin therapy. Cohorts were propensity score–matched in a 1:1 ratio on baseline characteristics, and imbalances were adjusted in multivariate analyses. Subgroup analyses were performed for people ≥65 years of age and those with a baseline A1C ≥9%. The primary endpoint was persistence with therapy at 12 months in the overall population. Secondary end points were treatment adherence, health care resource utilization (HCRU), costs, any hypoglycemia, and A1C change at 12 months.

Results. Cohorts each comprised 1,070 participants. Treatment persistence at 12 months was statistically significantly higher for iGlarLixi versus basal-bolus insulin therapy (43.7 vs. 22.3%, hazard ratio 0.51, 95% CI 0.46–0.57, adjusted P <0.001). Adherence was numerically higher for iGlarLixi, and hypoglycemia events, HCRU, and costs were numerically lower for iGlarLixi. A1C reduction from baseline was slightly greater for basal-bolus insulin. Results for both subgroups (≥65 years of age and baseline A1C ≥9%) were similar to those of the overall population.

Conclusion. In this observational study, initiation of once-daily iGlarLixi versus basal-bolus insulin was associated with higher persistence, lower hypoglycemia, and similar A1C reduction without increasing HCRU or costs regardless of age or A1C. iGlarLixi could be an alternative to basal-bolus insulin, particularly for older adults with type 2 diabetes who require treatment simplification with lower hypoglycemia risk.
Etiological Exploration of Gender-Based Violence against Male Survivors in Chongwe District, Zambia
Authors: Chibwe Musanshi , Muleya Gistered , Simui Francis
Published: March 2023

Gender-based violence has for a long time been considered as a women’s issue. For over three decades now, the 16 days of activism against Gender based violence which is commemorated worldwide has been on ending violence against women and girls. Recent studies, however, reveal that men too are victims of Gender based violence and they have continued to suffer in silence. Studies have further revealed that men usually do not report cases of Gender based violence which makes the statistics to be very low and attract little or no attention from stakeholders. GBV against men is largely overlooked and trivialized. It is not an issue that is talked about, yet men continue to suffer from multiple forms of GBV which are physical, sexual, psychological and emotional abuses. These forms of GBV have long lasting effects on male survivors yet very little attention has been directed towards establishing the causes of these abuses against men. Thus, the objective of this study was to establish the causes of Gender based violence against male survivors in Chongwe District. The study used a Phenomenological approach with a sample of 9 male survivors. Data was generated through individual interviews, observations, and focused group discussions. The study findings revealed the following causes: Failing to provide for the family, alcohol abuse, infidelity, and desire for women to dominate. It is therefore, recommended that stakeholders mandated to deal with issues of Gender based Violence adequately respond to male violence and abuse as opposed to trivializing their reports.
Devenir abyecto o el deseo de sentirse repugnada: cuerpo, desecho y monstruosidad en dos cuentos de María Fernanda Ampuero y Gilda Holst
Authors: Carretero Sanguino Andrea
Published: March 2023

Este artículo plantea el análisis de dos textos breves ¾“Reunión” de Gilda Holst, publicado originalmente en Más sin nombre que nunca (1989), y “Subasta”, que pertenece a Pelea de gallos (2018) de María Fernanda Ampuero¾ partiendo de un estudio de lo abyecto y  la corporalidad, con el objetivo de llevar a cabo una aproximación a su presencia e implicaciones en su vinculación con los cuerpos y la manera en que dicha conexión permite una lectura desde el concepto de devenir procedente de las teorías de Gilles Deleuze y Félix Guattari. Asimismo, la puesta en común de estos planteamientos con la teoría de Mabel Moraña permitirá establecer relaciones significativas entre las protagonistas de los cuentos y la figura del monstruo.
La migración desde la literatura fantástica centroamericana reciente: un acercamiento intertextual y Claudia Hernández
Authors: Sánchez Aramburu Patricia
Published: March 2023

El presente artículo explora la representación de los migrantes en tres relatos de Claudia Hernández a través de algunas herramientas de análisis propias de la literatura fantástica hispanoamericana, como son el concepto de fantástico de Ana María Barrenechea (1972), el concepto de neofantástico de Jaime Alazraki (1990) y el concepto de descontento realista de Alejandra Amatto (2020). Se utilizan estas herramientas para dar cuenta de la renovación estructural y temática de la literatura fantástica centroamericana reciente y de sus vínculos intertextuales con las obras de Jorge Luis Borges y Julio Cortázar. Los relatos que se analizan son “Las molestias de tener un rinoceronte”, “Manual del hijo muerto” y “Jon prefiere que no nos veamos por un tiempo”.
Dos modalidades no miméticas de influencia religiosa en la tradición latinoamericana
Authors: Cabrera Espinosa Claudia
Published: March 2023

Como parte del espectro de la literatura no mimética, encontramos una diversidad de textos influidos por la presencia de la divinidad, las distintas tradiciones religiosas o los libros sagrados. Para distinguirlos de lo fantástico, se han empleado términos como lo milagroso y lo maravilloso cristiano; sin embargo, considero necesario precisar y extender esta terminología para que resulte funcional para todas las narraciones en las que interviene lo divino, partiendo del paradigma de realidad intratextual y sin importar el sistema de creencias en el que estén ancladas. Este trabajo propone una nomenclatura que distinga lo milagroso de lo maravilloso y lo fantástico cuando el hecho sobrenatural entraña la mediación de una divinidad o de un ser proveniente de alguna tradición religiosa: lo maravilloso divino y lo fantástico divino.
La melancolía del revenant en "De tu misma especie" de Giovanna Rivero
Authors: Gutiérrez Piña Claudia L.
Published: March 2023

“De tu misma especie”, cuento perteneciente al libro Para comerte mejor (2015) de la escritora boliviana Giovanna Rivero, implica la reescritura de uno de los relatos míticos más prolíficos para el imaginario occidental, el de Orfeo, héroe que desciende al mundo de los muertos, retorna con la pérdida a cuestas y la mirada trastocada, la cual se conjuga con la figura del poeta melancólico de tipo simbolista, hundido en los misterios de las angustias del espíritu. Estas estructuras simbólicas y poéticas son encarnadas por el personaje suicida del relato, quien es una reescritura del fracaso que signa la “mirada órfica”, aquella de la que habla Maurice Blanchot, transportando el plano de lo simbólico del héroe mítico a la carnalidad del revenant.