bluuebunny/crossref_metadata_2025 huggingface dataset:
THE DEVELOPMENT OF EARLY MUSIC BROADCASTING IN THE CONTEXT OF THE AUDIO RECORDING MEDIA EVOLUTION (UNTIL 1970s)
Authors: Mazur Oleksandr
Published: June 2021

The purpose of the article is to determine the stages of development of music broadcasting and to reveal their features in the context of the evolution of audio recording means. The methodology consists of the application of general scientific and special methods, namely: information and system approaches, terminological and historical methods, as well as methods of analysis and generalization of source information, comparison and interrelation of theory and practice. Scientific novelty. The significance of musical resources has been brought to the development of radio communications and the early stages of development of musical radio communications have been clarified in the context of the evolution by means of audio recording. Conclusions. Radio has played one of the leading roles in the field of music and, conversely, without music, radio broadcasting has not received the appropriate technical development and, accordingly, would not have had such an impact on society. Clusters of music radio recordings on the rights of subsystems are connected to the metasystem of information communications. Music publishers, who were then the most influential part of the industry, allied with the musicians. At the time of birth, radio notes were the main musical product, and songwriters were real stars. However, when the whole world began to buy records instead of music, the power from publishers and singers passed to record companies and cooperated with them performers. In the early stages of its existence, musical radio broadcasting underwent an evolutionary path from the musical telegraph (1876), the first radio shows with magnetic recording (1914), the rapid development of radio engineering and recording technology (1920–1940), and 3-minute rock ‘n’ roll from artisanal records (1950s) to «pirate music», which was broadcast from ships (1960s). The study of the historical and cultural preconditions for the formation and development of musical radio broadcasting at an early stage in the context of the evolution of audio recording allowed to identify three main stages: «search» (1870–1920), 2) «competitive» (early 1920s – second half of the 1940s). .), 3) «vinyl-tape» (first half of the 1950s – 1970s). The term «music broadcasting» is proposed to mean technological means of sound transmission to an unlimited number of listeners of musical compositions and / or other musical information on the radio, as well as wired radio networks or packet-switched networks, classifying them as «active phonograms». , broadcast) and «passive phonograms» (performed a functional role and transferred to the archive).
Key words: Archive, Records, Storage, Music, Digitization, Radio.
Neoseiulus californicus McGregor: A Predatory Mite Species for Controlling Twospotted Spider Mites in Strawberries
Authors: Rondon Silvia I. , Price James F. , Liburd Oscar E. , Francis Roger , Cantliffe Daniel J.
Published: June 2021

Neoseiulus californicus McGregor (Acari: Phytoseiidae) is an oblong, tiny, mobile, predatory mite that feeds on a variety of prey (Fig. 1). It belongs to the suborder Acariforme in the Acari order. The division includes more than 30,000 described species included in the ancient group of Arachnida (Krantz, 1978). This document is HS1001, one of a series of the Horticultural Sciences Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Publication date: November 2004.
Cotton Stainer, Dysdercus suturellus (Herrich Schaeffer) (Insecta: Hemiptera: Pyrrhocoridae)
Authors: Mead Frank W. , Fasulo Thomas R.
Published: June 2021

Four species of "cotton stainers," also known as "red bugs," are known from Florida. However, the most important of these is the cotton stainer, Dysdercus suturellus (Herrich- Schaeffer). Morrill (1910) stated the cotton stainer was the most destructive cotton pest in Florida. Currently, the cotton stainer is a minor pest of cotton, and then only in the southern part of the state (Sprenkel 2000). This document is EENY-330 (originally published as DPI Entomology Circular 48), one of a series of Featured Creatures from the Entomology and Nematology Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Published: June 2004. Revised: March 2005.

EENY330/IN606: Cotton Stainer, Dysdercus suturellus (Herrich-Schaeffer) (Insecta: Hemiptera: Pyrrhocoridae) (ufl.edu)
Неопределенность как средство повышения качества аналитического контроля металлургической продукции
Authors: Аубакирова Р , Иващенко Е , Саурбаева Б , Даумова Г
Published: May 2021

Весь технологический процесс, начиная с добычи руды и заканчиваявыпуском готовой продукции, тесно связан с аналитическим контролем каждой стадии.В настоящее время в практику аналитических лабораторий крупных металлургическихпредприятий, к которым относится УК МК ТОО "Казцинк", прочно вошли физико-химическиеили инструментальные методы. Эти методы, отличающиеся экспрессностью, высокойизбирательностью и возможностью одновременного определения нескольких компонентов,вытеснили в большинстве случаев химические. В статье приводятся экспериментальныеданные анализа отвального шлака - отхода металлургического производства УК МКТОО "Казцинк" - методом атомной эмиссии с индуктивно-связанной плазмой. Атомныйспектральный анализ применяют в горнодобывающей промышленности и геологии,металлургической, металлообрабатывающей и химической промышленности и др. Результатыанализа были обработаны с позиций концепции неопределенности, что является весьмаактуальным в практике аналитической лаборатории.
Faktor-faktor yang meningkatkan kepatuhan perawat dalam penerapan prinsip enam benar pemberian obat
Authors: Nuryani Eni , Dwiantoro Luky , Nurmalia Devi
Published: May 2021

Perawat sebagai petugas yang langsung memberikan pelayanan kepada pasien, diharapkan mampu mengembangkan dan memelihara prosedur pemberian obat yang aman guna memberikan pelayanan dan proteksi terbaik bagi pasien. Studi menunjukan rendahnya kepatuhan perawat terkait penerapan prinsip enam benar pemberian obat. Ketidakpatuhan ini akan berdampak pada panjangnya lama rawat, biaya perawatan semakin bertambah, keracunan dan alergi terhadap obat, muntah hingga yang terburuk dapat menyebabkan kematian.  Tujuan studi ini adalah mengidentifikasi faktor yang meningkatkan kepatuhan perawat dalam penerapan prinsip enam benar pemberian obat. Studi ini menggunakan metode  Systematic Literatur Review dilaksanakan guna menelusuri berbagai faktor yang meningkatkan kepatuhan perawat dalam pemberian obat. Data yang diambil adalah artikel seputar enam benar prinsip pemberian obat dan faktor yang meningkatkan kepatuhan perawat. Data ditelusuri dari sumber terpercaya dalam Bahasa Inggris dan Indonesia dengan rentang penerbitan 2004 – 2019. Data yang terkumpul dilakukan critical appraisal tool sesuai dengan tujuan yang ingin dicapai menjadi 9. Hasil sintesa menunjukan terdapat beberapa faktor yang meningkatkan  kepatuhan perawat dalam pemberian obat yaitu pengetahuan dan sikap yang baik, pengawasan dan supervise yang baik dari ketua tim ataupun kepala ruangan, adanya SOP dan fasilitas pemberian obat yang memadai, motivasi perawat yang baik, pendidikan yang lebih tinggi, adanya sosialisasi dari kepala ruang tentang penerapan prinsip enam benar pemberian obat 6 kali dalam setahun, frekuensi audit dilakukan secara berkelanjutan 4 kali internal dan 2 kali eksternal, beban kerja yang tidak terlalu berlebihan serta perawat yang bekerja sudah lama. Faktor yang dapat meningkatkan kepatuhan perawat dalam penerapan prinsip enam benar pemberian obat adalah tingkat pengetahuan, sikap, supervisi, fasilitas pemberian obat, ketersediaan SOP, motivasi, pendidikan, sosialisasi, frekuensi audit, beban kerja dan lama kerja.
Removal of Cd (II) in Water Samples Using Modified Magnetic Iron Oxide Nanoparticle
Authors:   MS Student of Chemical Engineering, Islamic Azad University, South-Tehran Branch, Tehran, Iran., Kakaei Ahmad , Kazemeini Mohammad ,   Department of Chemical Engineering, Sharif University of Technology, Islamic Azad University, South-Tehran Branch, Tehran, Iran.
Published: June 2021

Background: Heavy metals, even at low concentrations, are harmful to human health and environment. Cadmium as a heavy metal is highly toxic and can cause serious threat to living organisms. This research was designed to evaluate the adsorption potential of modified magnetic iron nanoparticles by 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol ligand for the removal of cadmium ions from water solutions. Methods: This study was conducted in Ilam Branch, Islamic Azad University, Iran, in 2014. Modified magnetic iron nanoparticle was used as adsorbent for the removal of cadmium from aqueous solution. In batch extraction, the effects of parameters like pH of sample solution (3.0-11.0), initial metal concentrations (50-300) mgL-1), contact time (1.0-10 min) and adsorbent dose (10.0-60.0 mg) were studied on the adsorption process. Modified magnetite nanoparticle was presented as the adsorbent for the removal of cadmium ions from aqueous samples and later was confirmed by flame atomic absorption spectrometry. Results: The adsorption of cadmium ions on modified magnetite nanoparticles strongly depends on pH. The experimental isothermal data were analyzed using the Langmuir and Freundlich equations. The removal process followed the Langmuir isotherm. Maximum adsorption capacity for the adsorption of cadmium ions by the sorbent was 24.09 mgg-1. Conclusion: The method was successfully applied to adsorption of cadmium in water samples with satisfactory results. Other advantages include high capacity, good stability and fast adsorption kinetics. High pre-concentration factor was obtained easily by this method (120) and low analysis cost.
Clinical and Laboratory Findings of Lead Hepatotoxicity in the Workers of a Car Battery Manufacturing Factory
Authors:   Department of Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Dadpour Bita , Afshari Reza ,   Department of Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Mousavi Seyed Reza ,   Department of Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Kianoush Sina ,   Department of Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Keramati Mohamad Reza ,   Department of Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Moradi Vali Allah ,   Department of Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Sadeghi Mahmood ,   Department of Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Madani Sani Faezeh ,   Department of Cardiac Anesthesia Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Balali Mood Mahdi ,   Department of Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Published: June 2021

Background: Occupational lead poisoning is common in workers of some industries, but lead hepatotoxicity has rarely been reported. Several animal studies have revealed lead induced liver damage but clinical studies concerning the manifestations of lead induced liver toxicity in humans are scares. This study was designed to investigate the clinical manifestations and pathological parameters of hepatic dysfunction and its relationship with blood and urine lead concentrations in a car battery-manufacturing workers. Methods: This cross sectional study was carried out in Mashhad, Iran, during April-June 2011. One hundred and twelve workers underwent blood and urine sampling for determination of lead concentrations and liver function tests. Clinical signs and symptoms of possible lead hepatotoxicity were investigated. Results: Mean (±SD) age of the workers was 28.78 (±5.17) yr with a daytime work of 8.67 (±1.41) h and mean work duration of 3.89 (±2.40) yr. Mean blood lead concentration (BLC) and urine lead concentration (ULC) were 398.95 (±177.41) µg/l and 83.67(±50) μg/l, respectively. We found no correlation between the clinical findings and BLC or ULC. A weak correlation (R: 0.27, P=0.087) between serum alkaline phosphatase concentration and BLC was obtained. No significant relationship was found between other liver function tests and BLC or ULC. Conclusion: We found no specific clinical and laboratory abnormalities of liver in the workers of car battery manufacturer who had chronic lead toxicity. Further investigations with more specific laboratory tests such as LDH5 and gamma glutamyl transferase (GGT) as well as novel biomarkers of metal induced hepatotoxicity might be helpful in evaluating lead hepatotoxicity.
Evaluation of JAK2 (V617F) Mutation in Iranian Veterans with Delayed Complications of Sulphur Mustard Poisoning
Authors:   PhD of Hematopathology, Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Keramati Mohammad Reza , Sadeghian Mohammad Hadi ,   PhD of Hematopathology, Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Ayatollahi Hossein ,   PhD of Hematopathology, Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Basharati Mohammad Hosein ,   MD, Mashhad University of Medical Sciences, Mashhad, Iran., Basharati Mohammad Hosein ,   MD, Mashhad University of Medical Sciences, Mashhad, Iran., Jalili Mahshid ,   BSc of Laboratory Sciences, Mashhad University of Medical Sciences, Mashhad, Iran., Balali Mood5 Mahdi ,   Department of Toxicology, Mashhad University of Medical Sciences, Mashhad, Iran.
Published: June 2021

Background: Sulfur mustard was the most widely applied chemical warfare agent by the Iraqi army in Iran–Iraq war (1983-1988). Considering the role of sulfur mustard toxicity in hematopoietic neoplasms and also new role of JAK2 mutation in these neoplasms, we assessed this mutation and delayed hematologic complications in veterans exposed to sulfur mustard. Methods: This case control study was performed in Mashhad University of Medical Sciences, Mashhad, Iran in collaboration with Janbasan Foundation of Khorasan Razavi, Iran in 2012. The case group consists of 42 patients who exposed to sulfur mustard about 30 yr ago and the control group includes 30 healthy persons. For all subjects complete blood counts and ARMSpolymerase chain reaction for JAK2 (V617F) mutation was carried out. Data were analyzed by statistical software using independent sample t-testand Mann- Whitney U test. Results: JAK2 (V617F) mutation was detected, neither in the sulfur mustardveterans nor in the control group. Moreover no significant difference was detected in hematologic parameters between the two groups. Conclusion: Despite sulfur mustard can increase risk of tumor genesis especially hematologic neoplasms but this is probablyas result of other genetic mechanism apart from JAK2 mutation. Considering the health and importance of preventive measure for the sulfur mustard victims, we suggest other genetic aspects of tumor genesis to be assessed in these patients.
Expression of Collagen Type II and Osteocalcin Genes in Mesenchymal Stem Cells from Rats Treated with Lead acetate II
Authors:   Department of Biology, Faculty of Sciences, Islamic Azad University. Shiraz, Iran., Rafiei Hossein , Ashrafizadeh Milad ,   Veterinary Medicine Student, Faculty of Veterinary Medicine, Tabriz University. Tabriz, Iran.
Published: June 2021

Background: Lead is one of the sustainable metals with devastating effects on many tissues. This study, examined the adverse effect of lead poisoning on the gene expression of collagen type II and osteocalcin by mesenchymal stem cells (MSCs) cultured in chondrogenic and osteogenic media, respectively. Methods: We used 18 male Wistar rats, divided in 3 groups. In addition to libitum feed as the control, treatment I and treatment II groups were fed by distilled water, distilled water with a dose of 50 ppm lead acetate II and distilled water with a dose of 100 ppm lead acetate II, respectively, over a 2-month period. The MSCs of rat femur were isolated in DMEM medium. After the second passage, the media were replaced separately with chondrogenic and osteogenic media over another 21 days. Then, Collagen Type II and Osteocalcin genes expression were investigated by real time PCR. Results: Collagen Type II and Osteocalcin genes expression in treatments I and II groups showed meaningful decreases compared with that of the control group. Also, the concentration of collagen type II in treatment II group in chondrogenic medium was significantly reduced compared with Osteocalcin concentration in osteogenic medium. Conclusion: We found that poisoning with lead and its accumulation at doses of 50 and 100 ppm in femoral bone marrow of rats decreased the expression of the collagen type II and osteocalcin genes in MSCs and in the chondrogenic and osteogenic media, respectively.
PENGARUH QUENCHING TERHADAP KEKERASAN DAN KETANGGUHAN BAJA AISI 4340 PADA PROSES PACK CARBURIZING DENGAN KATALIS BARIUM KARBONAT (BaCO3) DAN KALSIUM KARBONAT (CaCO3)
Authors: Masoli Irsam Maulana , Supriyadi Slamet , Ma'mun Hisyam
Published: May 2021

Proses pack carburizing adalah proses meningkatkan kekerasan suatu materi dengan menambahkan unsur karbon dari luar. Penelitian ini bertujuan untuk mengetahui pengaruh proses pack carburizing terhadap nilai kekerasan dan ketangguhan baja AISI 4340 setelah dilakukan proses pack carburizing dengan variasi katalis dan media quenching. Materi yang digunakan dalam penelitian ini adalah baja AISI 4340 yang termasuk dalam jenis baja paduan rendah atau low alloy. Dalam penelitian ini jenis karbon yang digunakan adalah arang tempurung kelapa dengan penambahan katalis BaCO3 dan CaCO3 sebesar 30% dari berat arang, dipanaskan pada temperatur 900˚C dan holding time 180 menit, media quenching yang digunakan yaitu oli dan air. Untuk mengetahui hasil dari proses pack carburizing dilakukan pengujian kekerasan serta pengujian ketangguhan, dari penelitian yang telah dilakukan, diperoleh nilai kekerasan rata-rata tertinggi pada spesimen dengan penambahan katalis BaCO3 dan media quenching air sebesar 663.7 HV. Nilai ketangguhan mengalami penurunan dari raw material dengan nilai tertinggi sebesar 0.60 J/mm2 menggunakan katalis CaCO3 dan media quenching oli.
Revisão Sobre O Uso Da Cloroquina E Da Hidroxicloroquina No Tratamento Dos Pacientes Acometidos Pela Covid-19
Authors: Chaves Jhosyton Correia , Ott Thiely Rodrigues
Published: May 2021

O novo Coronavírus (SARS-Cov 2) foi identificado em Wuhan, China. Rapidamente se espalhou pelo mundo causando a Covid-19 e se tornou uma Pandemia, declarada em março, pela OMS. Visando obter um tratamento eficaz contra a doença, diversas pesquisas desenvolveram testes com dois medicamentos: Cloroquina e Hidroxicloroquina, associadas ou não a outros medicamentos. A Cloroquina e a Hidroxicloroquina são medicamentos antigos, utilizados principalmente para tratamento da Malária, além de serem medicamentos considerados essenciais em sistemas de Saúde pela OMS. Apesar de sua segurança e eficácia, existem efeitos tóxicos no uso dos medicamentos, especialmente da Cloroquina. Entre os efeitos relatados, estão a toxicidade ocular, enjoos, náuseas e problemas intestinais. Os dados presentes neste trabalho foram obtidos através de pesquisas na literatura utilizando palavras-chave específicas para encontrar resultados requeridos em portais como Scielo, Scholar Google, The New England Journal Of Medicine e The Lancet. O objetivo deste trabalho foi verificar a eficácia da Cloroquina e da Hidroxicloroquina, associadas ou não a outros medicamentos nos testes clínicos encontrados na literatura. Os resultados demonstram que os medicamentos, apesar de demonstrarem algum potencial in vitro, não indicam resultados benéficos in vivo, na maioria dos trabalhos consultados, não diminuindo o risco de morte, desenvolvimento ou sintomas da Covid-19. Um único artigo foi totalmente favorável ao uso, mas os dados e os métodos utilizados pelo mesmo contêm muitas limitações como a desistência de pacientes e a morte de outros ao longo dos dias de tratamento.
Analogous Labor To The Slave In The Brazilian Textile Industry
Authors: Neto Dalk Dias Salomão , Sousa Nicole Moreira Faria , Dendasck Carla Viana , Fecury Amanda Alves , Oliveira Euzébio de , Dias Claudio Alberto Gellis de Mattos
Published: May 2021

The institute of slavery has been present in humanity since the beginning of the existence of the human being. Slavery in Brazil has sustained the economy for centuries. Millions of Africans were taken from their homeland and placed in degrading conditions of life and work. The process of abolishing slavery was time-consuming and gradual. There were centuries of much struggle and suffering for the world to begin to realize the evil that slavery represents. Even after the abolition of slavery it was common to see the worker trapped in the field by debts, or by laws that empowered employers in relation to the employee. The objective of this research was to analyze the working conditions analogous to the slave in the Brazilian textile industry. It was carried out with bibliographic review and qualitative analysis. Due to his new clothing contemporary slave labor became invisible for some time. The factors that make it possible to commit this crime, even if in today, it is basically related to a tripod: impunity, poverty and profit. The situation of misery of the neediest population forces them to undergo types of work in subhuman conditions. These textile workers are mainly immigrants from neighboring, underdeveloped countries from Latin America. Brazil was one of the first countries in the world to recognize this type of work, and that jointly with the International Labor Organization (ILO) and oysternon-governmental entities seek to combat such criminal practice on their territory.
PRIORITIES AND CHALLENGES OF INTRODUCTION OF DIGITAL INNOVATIONS IN THE FIELD OF FINANCIAL SERVICES
Authors: Volokhova Liudmyla
Published: May 2021

The paper emphasizes that the transition to a digital economy is a reality dictated by time. The economy continues to grow at an incredible rate due to its ability to collect, use and analyze vast amounts of digital data. The advantages of digitalization are considered, which provide, first of all, numerous multiplier effects of digitalization, when all financial and production processes are included in a single information space. Over the last year, the vectors of e-commerce and banking, telecommunications, IT security, and other digital online tools have accelerated significantly. The real state of affairs shows that digital technology-based solutions are more efficient than traditional ones. The constant acceleration of digital trends will encourage investment not only in direct fintech projects, but also in technologies such as cybersecurity, fraud prevention and digital identity management. At the same time, in general, among the main risks and threats of digitalization, scientists include: the possibility of concentrating power in the market and strengthening monopolies; capture of new markets by transnational corporations; destabilization of the monetary system; growing dependence on leading companies in the field of information and communication technologies. At the same time, the fear of the dangers of digitalization has recently increased markedly. Most companies fear technological innovation due to the rise of cyber incidents. In the era of systemic interactions, digital technologies have a significant impact on social, ethical, legal and economic factors, so it is necessary to anticipate the possibility of maximizing the positive effects of technology and minimize the negative. New challenges can be used to destroy security and breach privacy. Given the fundamental difference between financial innovations and other types, the issues of nature, types, risks and limitations and challenges of implementing innovations in the field of financial services are considered. The paper considers extremely important issues of promoting the digital transformation of technological development for the insurance industry.
DEVELOPMENT OF INTERNET TRADING IN THE AGE OF DIGITALIZATION
Authors: Buzhymska Kateryna , Tsaruk Iryna
Published: June 2021

The article clarifies the concept of e-commerce and its significance in the modern conditions of the digital economy. It is proposed to consider e-commerce in the modern digitalization environment as a special business model that is rapidly evolving, constantly modernized and has its own characteristics. It is established that business on the Internet should cover the following aspects: establishing contacts with the target audience of customers by attracting attention (advertising, bright site design, etc.), selling goods and services, ensuring full control over payment, delivery and after-sales service. The set of economic, social, electronic-technological, organizational-legal nature factors influencing the spread of e-commerce is generalized. More than ten types of business models suitable for e-commerce have been identified, among the main and most used of which are the following models: B2C – company-consumer; B2B – company-company; C2B – consumer-company; C2C – consumer-consumer. The modern tendencies of formation and development of Internet trade in the world and in Ukraine in the conditions of a viral pandemic are investigated. The factors that will affect the additional growth of online sales in Ukraine are listed in the order of their consideration, among which the following are highlighted: new buyers on the Internet; insulation at home; increase in the frequency of purchases in the month following the isolation; the transition of some people to remote work; growth of online sales of everyday goods; falling purchasing power and consumer activity in the market. Proposals for further development of e-commerce in Ukraine are substantiated, among which are: continued formation of communication and telecommunication infrastructure; revision and harmonization of the current regulatory framework in the field of e-commerce; stimulating the development of online applications for business; organization of events on teaching the Internet and information technology in business; conducting information and educational campaigns among citizens; promoting the development of the electronic money market and the promotion of electronic wallets, etc.
Tumbuh-Tumbuhan Ubatan Dalam Hadith Tersenarai Kini Sebagai Terancam: Kajian Intertekstual Klasik-Data Saintifik
Authors: Binti Mohamad Rusni , Ahmad Thuraya
Published: June 2021

Medicinal plants have been used traditionally for thousands of years and gain their place today as pharmaceuticals in the medical industry. The medicinal value makes them the most important resource to human being as early as in the ancient time, and as well were used in perfumery until the golden age of Islam. However, today some of them face the threat of extinction due to lack of awareness in forms of uncontrolled use, logging and forest burning. As an initiative to delve into the deep, this study conducts an intertextual approach to interconnect between classical Arabic texts and contemporary sources. This study focuses on plants mentioned in Ṣaḥīḥ al-Bukhāriy in terms of risk of extinction listed by International Union for Conservation of Nature (IUCN). As a result, this study found that there are a total of five species categorized in the list. Two of them are critically endangered which is at a high risk of extinction and another two are vulnerable and a species is least concern which is low risk of extinction. This study recommends creating of awareness to the community about the values and benefits of plants that are useful to human, as well as responsibility of doing conservation to maintain its sustainability for future generations.
Faktor Jantina dan Kepuasan Klien dalam Perkhidmatan E-Kaunseling
Authors: Nor Zainudin Zaida , Hassan Siti Aishah , Ahmad Nor Aniza , Mohamad Yusop Yusni , Wan Othman Wan Norhayati
Published: June 2021

Memandangkan kemampuan internet mewujudkan prasarana yang sesuai untuk membina hubungan, pengamal kaunseling telah mengambil inisiatif memaksimumkan ruang internet ini. Satu perkhidmatan alternatif menolong melalui interaksi maya ini diwujudkan. E-Kaunseling telah mula mendapat perhatian kaunselor sebagai satu perkhidmatan alternatif yang ditawarkan kepada klien.Kajian ini bertujuan untuk meneroka sejauh mana keberkesanan perkhidmatan E-Kaunseling terhadap jantina. Kajian eksperimental-kuasi ini menggunakan reka bentuk Kumpulan Kawalan Ujian Pra Dan Ujian Pasca. Data kuantitatif diperolehi menggunakan soal selidik Client’s Satisfaction Inventory Short-Form (CSI-SF). Seramai 60 subjek kajian terlibat dan dijalankan dalam dua kumpulan kajian iaitu kumpulan kawalan menggunakan kaedah Kaunseling Bersemuka dan kumpulan eksperimen pula menggunakan kaedah E-Kaunseling.Dapatan menunjukkan tiada perbezaan antara jantina dan Kepuasan Klien dalam kedua-dua kaedah dan hasil analisis Anova Dua Hala menunjukkan tiada perbezaan utama (main interaction) antara Jantina dan Kepuasan klien. Hasil analisis lanjut menggunakan Anova Sehala menunjukkan kesan interaksi (interaction effect) bahawa klien lelaki mendapat lebih kepuasan dalam kaedah E-kaunseling manakala klien perempuan mendapat lebih kepuasan dalam kaedah Kaunseling bersemuka. Implikasi kajian ialah kepada kaunselor sekolah dalam menawarkan perkhidmatan e-kaunseling bagi membantu pelajar yang ingin mendapatkan perkhidmatan kaunseling di luar waktu persekolahan.
In view of the ability of the internet to create an appropriate relationship-building infrastructure, counselling practitioners have taken the initiative to optimize this internet space. An alternative service aims to establish this virtual interaction. E-Counselling has begun to catch the eye of counsellors as an alternative service offered to clients.This study aims to explore the effectiveness of E-Counselling services on gender.This quasi-experimental study uses the design of Pre-Test and Post-Test Control Groups. Quantitative data were obtained using the Client’s Satisfaction Inventory Short-Form (CSI-SF) questionnaire. A total of 60 participants were involved and conducted in two study groups, namely the control group using the Face-to-Face Counselling method and the experimental group using the E-Counselling method. Findings show no difference between gender and Client Satisfaction in both methods and the results of the Two-Way Anova analysis show no significant difference between Gender and Client Satisfaction. The results of further analysis using One-Way Anova show the interaction effect that male clients get more satisfaction in the E-counselling method while female clients get more satisfaction in the face-to-face counseling method. The implication of the study is for school counselors to provide e-counseling programs to support students who want to access counseling after school hours.
Virtual Screening and Biochemical Testing of Borocycles as Immunoproteasome Inhibitors
Authors: Kollár Levente , Frenczy György Gábor , Proj Matic , Gobec Martina , Gobec Stanislav , Sosič Izidor , Keserű György
Published: May 2021

Inhibition of the immunoproteasome (iCP) offers new opportunities in the treatment of cancer, autoimmune disorders and neurodegenerative diseases. Inspired by the success of boronic acids as proteasome inhibitors we have complied a virtual library of commercially available 5- and 6-membered borocycles and performed a structure based virtual screening against the chymotrypsin-like (β5i) subunit of the iCP. The top scored docking poses were visually inspected to select compounds for experimental testing. Six compounds with 5-membered ring and another six compounds with 6-membered ring were subjected to biochemical tests. All compounds exhibited detectable inhibitory activity at 100 µM concentration and these are the first reported cyclic boronic acid inhibitors of the iCP. Structural variations including the ring size and the substitution of the borocyles and the substitution pattern of the attached aromatic ring resulted in no major variation of the inhibitory activity. We propose that the evaluation of larger cycling boronic acid libraries is needed to fully elucidate the potential of these structures.
Modern Approaches to the Technology of Tablet Dosage Forms of Thioctic Acid (Review)
Authors: Egorova S. N. , Bulygina I. V. , Vorobeva N. V. , Chuvashova D. P. , Mustafina N. R.
Published: May 2021

Introduction. Thioctic (α-lipoic) acid is an endogenous antioxidant and is used for liver diseases, poisoning with salts of heavy metals, hyperlipidemia, atherosclerotic heart disease, neuropathy, insulin-resistant forms of diabetes mellitus, etc. technologies for producing tableted medicinal preparations of thioctic acid, necessary for the pharmaceutical development of thioctic acid tablets at pharmaceutical industry enterprises.Text. The review considers the physicochemical properties of the pharmaceutical substance thioctic acid, the features of its pharmaceutical and technological properties, and compatibility with excipients. In the technology of thioctic acid tablets, methods of direct compression and compression with preliminary wet granulation, including those using organic solvents, are used. To increase photostability, thioctic acid tablets are coated. Information on excipients in the composition of core tablets and film coat of thioctic acid tablets registered in Russia is presented. The problems of tabletting thioctic acid are described: sintering of the granulate during the drying process, adhesion of the tabletting mass to the pressing tool and the resulting unevenness of the tablet surface. The ways of optimizing the tabletting process of thioctic acid using various compositions of excipients, improving the flowability of a pharmaceutical substance both during its synthesis and as a result of technological processing, choosing the optimal modes of granulation, drying, pressing are considered.Conclusion. As a result of the analysis of the literature data, the features of the technology for producing thioctic acid tablets were revealed, which are due to the high content of the pharmaceutical substance in tablets (up to 600 mg), the need to use a minimum amount of excipients (from 27 to 51 %), poor flowability, and low melting point of the pharmaceutical substance. Improvement of compressibility and prevention of adhesion can be achieved by using the pharmaceutical substance thioctic acid of a certain granulometric composition, auxiliary substances of the basic nature and a high content of glidants (up to 6 %). The identified manufacturing features should be taken into account in the pharmaceutical development of thioctic acid tablets.
Исполняя долг гражданина и врача…
Authors: Николаев Валериан
Published: May 2021

Статья посвящена биографии одного из первых военных врачей, участника Первой мировой войны из коренных народов Сибири И. Н. Скрябина. Он в 1914 г. окончил медицинский факультет Императорского Томского университета. После окончания был сразу призван на фронт Первой мировой войны. Попал в плен, знание немецкого языка спасло его от расстрела. Вернувшись в Россию, участвовал в Гражданской войне бригадным врачом Уральской дивизии. В 1920 г. вернулся в родную Якутию. Он приложил много сил и энергии, знания и опыт в дело становления здравоохранения и его дальнейшего развития в Якутии. Еще много бы он сделал для здравоохранения, но подорванное войной здоровье прервало его жизнь в возрасте 33 лет 7 декабря 1923 г. в г. Якутске.

The article is devoted to the biography of one of the first military doctors, a participant in the First World War from the indigenous peoples of Siberia I.N. Skryabin. In 1914 he graduated from the Medical Faculty of the Imperial Tomsk University. After graduation, he was immediately called up to the front of the First World War. He was captured, knowledge of the German language saved him from being shot. Returning to Russia, he participated in the Civil War as a brigade doctor of the Ural division. In 1920 he returned to his native Yakutia. He put a lot of effort and energy, knowledge and experience into the establishment of healthcare and its further development in Yakutia. He would have done a lot for health care, but his health, undermined by the war, interrupted his life at the age of 33 on December 7, 1923 in Yakutsk
The Phenomenon of Human difference: surgeon-inventor, scientist-researcher, writer-prose writer Innokenty Innokentyevich Vinokurov
Authors: Vinokurova Oksana , Vinokurova Maria
Published: May 2021

Nature-oriented upbringing and significant moments of life that accompanied Innokenty Innokentyevich Vinokurov from childhood became the basis for the formation of his personality as a surgeon, scientist, and writer. The formation of a professional's personality took place in the extreme conditions of the Far North, then in the team of a large scientific institution, which motivated the search for health-saving methods of surgical interventions and constant self-improvement of the level of one's qualifications. An innovative approach to professional activity has become the core of many scientific discoveries and inventions. Achievement of qualitatively significant results in the field of practical surgery, organization of the health care system, scientific activities were successfully combined with the development of the creative potential of Vinokurov I. as a writer. Bright literary works created by a talented writer are evidence of the versatility of his talent. The source of his success was not only natural talent, character traits, but also love for his native land and for his people. The life of a multifaceted personality was brutally interrupted by the terrible epidemic of the 21st century caused by the new coronavirus infection COVID-19. The study of the personality of the outstanding son of the Evenk people Innokenty Vinokurov is an actual topic of scientific knowledge of various fields of science.
Moderate and severe symptoms of anxiety and depression are increased among female medical students during the COVID-19 pandemic
Authors: Sartorão Filho Carlos Izaias , Rodrigues Wilson Conte de Las Villas , Castro Ricardo Beauchamp de , Marçal Arlete Aparecida , Pavelqueires Shirlene , Takano Luiz , Oliveira Wilson Luis de , Sartorão Neto Carlos Izaias
Published: June 2021

Background: Emotional disorders in medical students are expected and deserve more attention, especially during the COVID-19 Pandemic. Objective: Evaluate anxiety and depression disorders among medical students during the COVID-19 Pandemic. Methods:  A cross-sectional study at a private medical college in Brazil, two months after stay-at-home order and postponed classes due to the COVID-19 Pandemic. A survey among medical students was conducted in May 2020, using questionnaires regarding social and demographic status, the GAD-7 for symptoms of anxiety, and the PHQ-9 for symptoms of depression. Results: A total of 340 of 347 (97.98%) medical students participated. The average GAD-7 score was 9.18 (±4.75), and the average PHQ-9 score was 12.72 (±6.62). The results indicate a significant positive relationship between GAD-7 and females (F=5.816 P=.016). Using a cut-off score of 10 for GAD-7, 157 (46.17%) students were identified with moderate or severe anxiety symptoms. For the PHQ-9 score, using a cut-off of 10 219 (64.41%), students were recognized with moderate or severe symptoms of depression; the results indicate a significant positive relationship between the PHQ-9 and females (F=5.640 P=.018). Conclusion: The analysis demonstrated a significantly higher prevalence of moderate and severe anxiety    and depression symptoms among female medical students during the COVID-19 Pandemic.
Uso do pó de rocha basáltica como fertilizante alternativo na cultura da soja
Authors: Alovisi Alessandra Mayumi Tokura , Rodrigues Rodrigo Bastos , Alovisi Alves Alexandre , Tebar Mariana Manzato , Villalba Laurilaine Azuaga , Muglia Giuliano Reis Pereira , Soares Milena Santo Palhano , Tokura Luciene Kazue , Cassol Cleidimar João , Silva Robervaldo Soares da , Tokura Willian Isáo , Gning Adama , Kai Priscila Marques
Published: June 2021

Objetivou-se com o presente estudo avaliar o efeito residual da adição de pó de rocha basáltica associado ou não a adubação química, sobre os atributos químicos do solo e produtividade da cultura da soja. O delineamento experimental foi de blocos casualizados em esquema fatorial (5x2), testando, cinco doses de pó de rocha (0; 2,5; 5,0; 7,5 e 10,0 Mg ha-1), com ou sem adubação química de NPK na formulação 05-25-06, com quatro repetições. O experimento foi conduzido em condições de campo. Foram avaliadas as características agronômicas de altura final de plantas, altura da inserção do primeiro legume, diâmetro do coleto, peso de 1000 grãos, produtividade da soja e os atributos químicos do solo. A adubação química influenciou os teores dos nutrientes P, K e Mn no solo. Na camada de 0-10 cm houve aumento dos teores de P e K. Na camada de 10-20 cm ocasionou redução no teor de Mn. O residual da aplicação das doses de pó de basalto ocasionou a redução das concentrações foliares de P, Cu, Zn. A adubação química complementar favoreceu a redução da concentração do Mg foliar. Altura de plantas, diâmetro do coleto, peso de grãos e produtividade foram maiores nos tratamentos que receberam a adubação química. A pequena liberação dos nutrientes do pó de basalto indica que tal material não pode ser utilizado como a principal fonte de nutrientes às plantas.
Aggregation of adult abalone Haliotis discus hannai during the spawning season, and its associations with seasonal and interannual changes in the macroalgal community
Authors: Hayakawa J , Nakamoto K , Kodama M , Kawamura T
Published: June 2021

Clarification of the biological and/or physical factors determining the location requirements for spawning aggregations is necessary for understanding the population dynamics of free-spawning marine animals. We monitored the density of adult abalone Haliotis discus hannai on 2 types of artificial reefs with different heights (tall and short blocks) and the surrounding seabed area in Otsuchi Bay, northeast Japan, from February 2016 to December 2019. In addition, the number of neighboring adults located within a 50 cm radius from each individual was counted from March 2017 to December 2019. Algal succession in the 3 types of location (tall and small blocks, seabed) was monitored and compared with temporal fluctuations in adult abalone density. Our results show that the fluctuations in density were different among the 3 locations, especially during the spawning season (August-October). On tall blocks, clear increases in adult abalone density and number of neighboring adults were confirmed during the spawning seasons in 2016 and 2019. In contrast, there was no clear increase in the adult density on small blocks and surrounding bottom areas. Aggregations on the tall blocks clearly differed among the 4 years, and the difference was considered to be influenced by differences in the macroalgal species and coverage during the spawning season. This is the first study to report that a difference in phenology among algal species is a key factor in the formation of spawning aggregations of a free-spawning marine animal.
Strategic view of internationalization process, a case study
Authors: DEMİR Prof. Dr. Sertif , KOÇAK Associate Prof. Dr. R. Dilek
Published: May 2021

This study aims at examining the Slovenian airdrome multinational corporation construction Company, in OLI paradigm factors, notably focusing on how the OLI paradigm can be utilized to explain the course of the company for the decision of internationalization production. The major outcome of this study demonstrates that among the OLI paradigm, ownership and location advantages can best explain the Company’s internationalization of production as the Company has the monopolistic advantage in production airdrome in Balkans, at old Soviets countries, and the Middle East and those regions present locational advantage because of their effective demand capacity, low labor costs, free entry markets.
FAKTOR-FAKTOR PENGARUH KEGAGALAN PERATURAN DAERAH NOMOR 5 TAHUN 2007 TENTANG LARANGAN PELACURAN DI KABUPATEN BANTUL DAERAH ISTIMEWA YOGYAKARTA
Authors: Dewi Astri Candra , Al-Hamdi Ridho
Published: May 2021

Artikel ini mengkaji tentang faktor-faktor yang mempengaruhi gagalnya Peraturan Daerah (Perda) Nomor 5 Tahun 2007 tentang larangan pelacuran di Kabupaten Bantul. Tujuan penelitian adalah mengetahui evaluasi Perda Nomor 5 Tahun 2007 tentang larangan pelacuran di Kabupaten Bantul serta faktor-faktor yang mempengaruhi gagalnya Perda tersebut. Secara metodologis, studi ini merupakan penelitian kualitatif dengan pendekatan studi kasus. Pengumpulan data dilakukan dengan teknik dokumentasi dan wawancara mendalam. Studi ini menggunakan enam indikator teori evaluasi kebijakan yang dikembangkan oleh William Dunn, yaitu efektifitas, efisiensi, kecukupan, responsivitas, perataan, dan ketepatan. Untuk mengukur evaluasi Perda tersebut, studi ini menggunakan enam indikator yaitu efektivitas, efisiensi, kecukupan, responsivitas, perataan dan ketepatan. Temuan dari studi ini menyatakan, bahwa dari enam indikator, tiga indikator dikategorikan tidak berhasil dan tiga indikator lainnya dapat dianggap berhasil. Namun demikian, faktor-faktor yang mempengaruhi keberhasilan Perda ini adalah efektivitas, kecukupan, dan responsivitas. Dengan demikian, evaluasi terhadap Perda ini dapat disimpulkan tidak berhasil alias gagal. Karena itu, pemerintah setempat perlu melakukan sejumlah upaya serius untuk peningkatan pengawasan terhadap berjalannya Perda.
Examining Public Satisfaction of Lombok Tengah Regency Civil Registry Service office Administrative Service Based on Government System
Authors: Surya Ida
Published: May 2021

ABSTRACT. Public service is something that needed by the public. So in this regard, the government as an official public body has the duty and responsibility to provide the best service to the public itself. But the efforts made as a public service provider do and work, certainly not able to provide satisfaction to the public itself. Satisfaction with a service is one of the rights that obtained by someone. "In accordance with the Universal Declaration of Human Rights, ideals about free human beings, who enjoy civil and political freedom, and freedom from fear and poverty can only be achieved, if conditions are created where everyone can enjoy civil rights and its politics and economic, social and cultural rights”. To obtain input/information about public satisfaction in the field of population administration and civil registration services in Lombok Tengah Regency, researchers tried to conduct research, with survey methods, in order to obtain input from the public how about public services performed by public service providers in Lombok Tengah District, in the area of ​​population administration and civil registration services.