bluuebunny/crossref_metadata_2025 huggingface dataset:
Angka Kejadian Balita Stunting di Wilayah Kerja Puskesmas Ibrahim Adjie Bandung Sebelum dan Saat Masa Pandemi Covid-19
Authors: Tia Putriani Noni , Indriati Maya , Rosita Rosita
Published: January 2022

Stunting (kerdil) adalah kondisi dimana balita memiliki panjang atau tinggi badan yang kurang jika di bandingkan dengan umur. Kejadian pandemi mengakibatkan timbulnya berbagai risiko perburukan kejadian stunting di Indonesia, ditambah lagi pemantauan kasus yang masih minim. Tujuan penelitian ini yaitu  untuk mengetahui gambaran angka kejadian dan karakteristik balita stunting di wilayah kerja Puskesmas Ibrahim Adjie sebelum pandemi tahun 2019 dan saat masa pandemi covid 19 tahun 2020. Penelitian ini menggunakan metode analisis deskriptif dengan pendekatan kuantitatif. Data yang digunakan pada penelitian ini adalah data sekunder berupa Laporan BPB UPT Puskesmas Ibrahim Adjie Bulan Agustus Tahun 2019- 2020. Hasil penelitian ini menunjukan jumlah kejadian stunting berdasar angka status gizi BB/TB dan TB/U UPT Puskesmas Ibrahim Adjie sebelum dan sesudah pandemi mengalami penurunan. Pada tahun 2019, berdasar angka status gizi BB/TB, terdapat sebanyak 74 anak usia 24-39 bulan yang mengalami , sedangkan pada tahun 2020 angka kasus tercatat sebesar 61 anak. Jumlah kejadian stunting berdasar angka status gizi TB/U sebelum dan sesudah pandemi mengalami penurunan yang sama. Pada tahun 2019 terdapat sebanyak 177 anak usia 24-59 bulan yang  mengalami, sedangkan pada tahun 2020 angka kasus tercatat sebesar 125 anak. Berdasarkan hasil penelitian tersebut dapat disimpulkan bahwa justru terjadi penurunan angka kasus stunting di masa pandemi.
Hubungan Dismenorea terhadap Aktivitas Belajar Mahasiswi di Prodi DIII Kebidanan STIK Immanuel Bandung
Authors: Tiana Hani
Published: January 2022

Nyeri haid (dismenore) merupakan salah satu gangguan saat menstruasi dan salah satu aktivitas yang terganggu akibat terjadinya dismenore pada mahasiswi adalah aktivitas belajar. Survei pendahuluan yang dilakukan peneliti menunjukan bahwa mahasiswi yang mengalami dismenore merasa tidak nyaman dan tidak bersemangat dalam proses pembelajaran, sehingga hal ini membuat mahasiswi tidak masuk perkuliahan. Penelitian ini bertujuan untuk mengetahui hubungan Dismenore terhadap aktivitas belajar mahasiswi di Prodi DIII Kebidanan STIK Immanuel Bandung. Jenis penelitian ini adalah penelitian kuantitatif dengan desain cross sectional , populasi dalam penelitian ini adalah mahasiswi yang mengalami dismenore yaitu sebanyak 28 orang. Berdasarkan analisi data diperoleh Dari 28 orang mahasiswi yang aktivitas belajarnya terganggu karena mengalami dismenore adalah sebanyak 11 orang (39,3%) sedangkan mahasiswi yang aktivitas belajarnya tidak terganggu saat mengalami dismenore adalah sebanyak 17 orang (60,7%).  Dari hasil jumlah mahasiswi tersebut ditemukan bahwa dari 11 orang mahasiwa yang aktivitasnya terganggu adalah mahasiswi yang mengalami dismenore dengan intensitas nyeri berat. Analisis data menggunakan chi square dengan hasil penelitian menunjukan bahwa terdapat hubungan yang signifikan antara kejadian dismenore terhadap aktivitas keluarga (0,000<0,05). Kesimpulan dari hasil penelitian ini yaitu terdapat hubungan antara kejadian dismenore terhadap aktivitas belajar mahasiswi di prodi DIII Kebidanan STIK Immanuel.
Hubungan Penggunaan Komputer dan Gadget Terhadap Penurunan Tajam Penglihatan
Authors: Mayarani Mayarani , Nanda Aulia Risfa
Published: January 2022

Pengguna internet di Indonesia yang berasal dari kalangan anak-anak dan remaja mencapai 30 juta. Pada pengguna komputer, sebagian besar darinya menghabiskan waktu berjam-jam menatap layar komputer, tanpa mengistrahatkan mata. Dimana penggunaan komputer dalam waktu yang cukup lama tanpa istrahat menyebabkan kelelahan pada mata dan risiko terjadinya stres yang berulang pada otot-ototmata yang bisa berlanjut pada penurunan fungsi otot-otot mata sehingga berefek pada gangguan penglihatan/penurunan visus. Tujuan penelitian ini adalah untuk mengetahui hubungan penggunaan komputer dan gadget terhadap penurunan tajam penglihatan. Jenis data yang digunakan penulis dalam penelitian ini adalah data skunder yaitu data yang diperoleh dari jurnal, dan internet. Metode yang digunakan dalam penelitian ini adalah studi literatur, yaitu membandingkan 5 judul artikel nasional dari tahun 2013 sampai dengan tahun 2019. Hasil studi menunjukkan terdapat kesamaan bahwa ada hubungan antara penggunaan komputer dan Gadget dengan intensitas waktu yang lama dan jarak pendang yang dekat, akan mengakibatkan penurunan tajam penglihatan. Dengan demikian saran yang dapat dibentuk sebaiknya pengguna Gadget untuk tidak bermain gadget dalam intensitas waktu yang lama dan  lakukan kiat 20-20-20, yaitu mengalihkan pandangan dari layar setiap 20 menit untuk menatap objek yang berjarak sekitar 20 kaki atau 6 meter selama 20 detik.Dengan jarak maksimal 30 cm ketika menatap layar gadget atau komputer. Menyesuaikan posisi layar, untuk mengurangi refleksi cahaya dan seringlah berkedip untuk melembabkan mata.
PROFITABILITY AND WORKING CAPITAL MANAGEMENT: EVIDENCE FROM THE WARSAW STOCK EXCHANGE
Authors: Jaworski Jacek , Czerwonka Leszek
Published: January 2022

The aim of this paper is to identify the relationships between measures of working capital management (cash conversion cycle /CCC/, working capital value /WC/ and the financial liquidity /CR/) and profitability of companies listed on the Warsaw Stock Exchange. The research material consisted of data of 326 companies from 1998–2016. The analysis revealed significant non-linear relationship between WC, CR and profitability. When WC and CR values grow, profitability increases, but at a slower pace. However, there is a linear negative relationship between CCC and profitability. The results are influenced by the industry and the GDP growth. This indicates that profit-driven entrepreneurs try to delay payments to suppliers. They pay off bank loans from the funds thus generated. This study contributes to the verification of theories linking profitability with working capital management with emphasis on the influence of the industry. The results have practical implications: companies with growing profitability should not lose sight of the shortening CCC when paying off short-term loans; in some industries decreasing profitability while CR values grow may mean problems with the efficient use of current assets.
SYNTHESIS OF FEOOH AND FEOOH@ZNO BY HYDROTHERMAL METHOD AND THE ADSORPTION OF S2- IN WASTEWATER
Authors: Ge Baocai , Li Fen , Meng Fanzhu , Yang Ying , Yu Cailian
Published: January 2022

FeOOH and FeOOH@ZnO were prepared by hydrothermal synthesis, and their structures and adsorption properties toward S2− were studied. The results showed that too high hydrothermal temperature was not conducive to the adsorption of S2−. However, using sodium dodecyl sulfate (SDS) for FeOOH preparation and adding nanometer ZnO (FeOOH@ZnO) could significantly improve the adsorption of S2− by FeOOH, and adsorption removal rate was close to 90.0% and adsorption amount was 87.5 mg·g−1. The structural analysis showed that the modification of FeOOH by SDS and the addition of nano-ZnO resulted in the reduction in size of the FeOOH particles, forming amorphous inclusion structure with ZnO present inside and FeOOH outside. The specific surface area of FeOOH@ZnO was found to be higher than that of FeOOH. Therefore, it is beneficial to the adsorption of S2−. XPS fitting results showed that ferrous deposits appeared in the process of adsorption of S2− by FeOOH@ZnO, and it was considered that the oxygen of Fe = O was replaced with sulfur.
A Multitransition Methanol Maser Study of the Accretion Burst Source G358.93–0.03-MM1
Authors: Bayandina O. S. , Brogan C. L. , Burns R. A. , Chen X. , Hunter T. R. , Kurtz S. E. , MacLeod G. C. , Sobolev A. M. , Sugiyama K. , Val’tts I. E. , Yonekura Y.
Published: January 2022

We present the most complete to date interferometric study of the centimeter-wavelength methanol masers detected in G358.93−0.03 at the burst and post-burst epochs. A unique, near-IR/(sub)millimeter-dark and far-IR-loud massive young stellar object accretion burst was recently discovered in G358.93−0.03. The event was accompanied by flares of an unprecedented number of rare methanol maser transitions. The first images of three of the newly discovered methanol masers at 6.18, 12.23, and 20.97 GHz are presented in this work. The spatial structure evolution of the methanol masers at 6.67, 12.18, and 23.12 GHz is studied at two epochs. The maser emission in all detected transitions resides in a region of ∼0.″2 around the bursting source and shows a clear velocity gradient in the north–south direction, with redshifted features to the north and blueshifted features to the south. A drastic change in the spatial morphology of the masing region is found: a dense and compact “spiral” cluster detected at epoch I evolved into a disperse, “round” structure at epoch II. During the transition from the first epoch to the second, the region traced by masers expanded. The comparison of our results with the complementary Very Large Array, very long baseline interferometry, Submillimeter Array, and Atacama Large Millimeter/submillimeter Array maser data is conducted. The obtained methanol maser data support the hypothesis of the presence of spiral arm structures within the accretion disk, which was suggested in previous studies of the source.
Solar Wind Ion Sputtering of Sodium from Silicates Using Molecular Dynamics Calculations of Surface Binding Energies
Authors: Morrissey Liam S. , Tucker Orenthal J. , Killen Rosemary M. , Nakhla Sam , Savin Daniel W.
Published: January 2022

For nearly 40 yr, studies of exosphere formation on airless bodies have been hindered by uncertainties in our understanding of the underlying ion collisional sputtering by the solar wind (SW). These ion impacts on airless bodies play an important role in altering their surface properties and surrounding environment. Much of the collisional sputtering data needed for exosphere studies come from binary collision approximation (BCA) sputtering models. These depend on the surface binding energy (SBE) for the atoms sputtered from the impacted material. However, the SBE is not reliably known for many materials important for planetary science, such as plagioclase feldspars and sodium pyroxenes. BCA models typically approximate the SBE using the cohesive energy for a monoelemental solid. We use molecular dynamics (MD) to provide the first accurate SBE data we are aware of for Na sputtered from the above silicate minerals, which are expected to be important for exospheric formation at Mercury and the Moon. The MD SBE values are ∼8 times larger than the Na monoelemental cohesive energy. This has a significant effect on the predicted SW ion sputtering yield and energy distribution of Na and the formation of the corresponding Na exosphere. We also find that the SBE is correlated with the coordination number of the Na atoms within the substrate and with the cohesive energy of the Na-bearing silicate. Our MD SBE results will enable more accurate BCA predictions for the SW ion sputtering contribution to the Na exosphere of Mercury and the Moon.
Strong H2O and CO Emission Features in the Spectrum of KELT-20b Driven by Stellar UV Irradiation
Authors: Fu Guangwei , Sing David K. , Lothringer Joshua D. , Deming Drake , Ih Jegug , Kempton Eliza M. -R. , Malik Matej , Komacek Thaddeus D. , Mansfield Megan , Bean Jacob L.
Published: January 2022

Know thy star, know thy planetary atmosphere. Every exoplanet with atmospheric measurements orbits around a star, and the stellar environment directly affects the planetary atmosphere. Here we present the emission spectrum of ultra-hot Jupiter KELT-20b which provides an observational link between host-star properties and planet atmospheric thermal structure. It is currently the only planet with thermal emission measurements in the T
eq ∼ 2200 K range that orbits around an early A-type star. By comparing it with other similar ultra-hot Jupiters around FGK stars, we can better understand how different host-star types influence planetary atmospheres. The emission spectrum covers 0.6–4.5 μm with data from TESS, HST WFC3/G141, and Spitzer 4.5 μm channel. KELT-20b has a 1.4 μm water feature strength metric of

S

H

2

O

= −0.097 ± 0.02 and a blackbody brightness temperature difference of 528 K between WFC3/G141 (T
b
= 2402 ± 14 K) and Spitzer 4.5 μm channel (T
b
= 2930 ± 59 K). These very large H2O and CO emission features combined with the A-type host star make KELT-20b a unique planet among other similar hot Jupiters. The abundant FUV, NUV, and optical radiation from its host star (Teff = 8720 ± 250 K) is expected to be the key that drives its strong thermal inversion and prominent emission features based on previous PHOENIX model calculations.
The body between meaning and form: kinesiological analysis and typographical representation of movement in Sign Languages
Authors: Chevrefils Léa , Danet Claire , Doan Patrick , Thomas Chloé , Rébulard Morgane , Contesse Adrien , Dauphin Jean-François , Bianchini Claudia S.
Published: January 2022

Most of the research on Sign Languages (SLs) and gesture is characterized by a focus on hands, considered the sole body parts responsible for the creation of meaning. The corporal part of signs and gestures is then blurred by hand dominance. This particularly impacts the linguistic analysis of movement, which is described as unstable, even idiosyncratic. Boutet’s Kinesiological Approach (KinApp) repositions the speaker’s body at the core of meaning emergence: how this approach considers and conceptualizes movement is the subject of this article. First, the reasons that led SLs researchers to neglect the analysis of the sign signifying form, focusing on the hand, are exposed. The following part introduces KinApp which, through a radical change of point of view, allows revealing the simplicity and stability of movement: understanding the cognitive and motor reasons for this stability is the subject of research whose methodology is described. Setting the body at the center of analysis requires a descriptive model capable of accounting for the SLs signifying form, thus going beyond existing transcription systems. The last part is devoted to the presentation of Typannot, a new transcription system, aimed not only at a kinesiological description of SLs but also at assisting researchers to modify how they understand and analyze movement.
Comparative analysis of the mitogenomes of two Corydoras (Siluriformes, Loricarioidei) with nine known Corydoras, and a phylogenetic analysis of Loricarioidei
Authors: Sun Cheng-He , Huang Qi , Zeng Xiao-Shu , Li Sha , Zhang Xiao-Li , Zhang Ya-Nan , Liao Jian , Lu Chang-Hu , Han Bo-Ping , Zhang Qun
Published: January 2022

Corydoras is a speciose catfish genus from South America with widely investigated phylogenetic and evolutionary relationships. The complete mitogenomes of C. aeneus and C. paleatus were sequenced, assembled, and annotated using next-generation sequencing. The genome arrangements, gene contents, genome structures, base compositions, evolutionary features, codon usage, and tRNA structures of the two mitogenomes were compared and analyzed with nine published mitogenomes of Corydoras. Phylogenetic analysis was performed using concatenated nucleotide sequences with 13 protein-coding genes and two rRNAs with 44 mitogenomes of Siluriformes. These results provide information on the mitogenomes of eleven Corydoras species and evolutionary relationships within the suborder Loricarioidei, which may be applicable for further phylogenetic and taxonomic studies on Siluriformes and Loricarioidei.
« On n'a pas le temps d'aider les élèves en difficulté ! »
Authors: Broccolichi Sylvain , Garcia Sandrine
Published: January 2022

À la suite de plusieurs recherches convergentes, cet article écrit à quatre mains analyse la façon dont la Nouvelle Gestion Publique de l’organisation scolaire a intensifié les difficultés des professeurs des écoles et infléchi leurs pratiques de tri des élèves. Les doubles contraintes auxquelles ces enseignants sont confrontés résultent en particulier d’une inflation de tâches bureaucratiques chronophages conjuguée à une responsabilisation accrue à l’égard d’objectifs ambitieux d’inclusion d’élèves en situation de handicap et de « réussite de tous ». Sous la menace croissante d’échecs risquant de leur être imputés, beaucoup en sont réduits à systématiser le travail d’imputation d’insuffisances parentales ou d’étiologie médicale, en réponse aux difficultés constatées et aux échecs pressentis.
Theacrine does not enhance physical performance or training status over 8 weeks
Authors: Cerqueira H. Santa Capita , Filho H. Tourinho , Corrêa M. , Martinelli C.E.
Published: January 2022

Fatigue is a condition that may affect physical performance during training sessions. Consequently, this will impact training performance and will also affect the performance of the individual in the long term. Caffeine is extensively used to counteract fatigue; however, it contains several side effects. Theacrine might be used as an alternative to caffeine, providing the same benefits without the side effects. The current study aimed to investigate the effects of 8 weeks of supplementation with theacrine on physical performance and training status of young amateur athletes. Twenty-two subjects were divided into two groups – Theacrine Group (T) and Placebo Group (P) – and evaluated before and after the intervention period. Evaluations included physical tests and hormonal values of insulin like growth factor (IGF)-I and IGF binding protein (IGFBP)-3, used as markers of training status. Results demonstrated that theacrine was not capable of promoting benefits regarding the physical performance of the subjects. It also had no effects on serum secretion of IGF-I and its binding protein, IGFBP-3. Therefore, the findings of this study do not support the use of theacrine to increase physical performance.
Temperature-modified density effects in the black soldier fly: low larval density leads to large size, short development time and high fat content
Authors: Opare L.O. , Holm S. , Esperk T.
Published: January 2022

The effects of biotic and abiotic factors on insect life histories have been extensively studied. However, the impact of some crucial aspects, such as larval density (crowding) and the effects of environmental interactions, have often been overlooked. This study aims to determine the effects of larval density and temperature on life-history traits in the black soldier fly (BSF). Our results showed an increase in prepupal mass, pupal mass, prepupal-to-pupal mass loss, survival, prepupal fat content, adult mass, adult longevity and a reduction in larval and pupal development time at low densities. Larval density was maintained throughout the entire larval period and larval survival was determined at the 4th instar and at prepupation. Larvae were reared at three different larval densities (1, 5 and 10 larvae/cm2), at three temperature treatments (23, 27 and 30 °C) and food was provided ad libitum. High densities, on the contrary, resulted in an increase in development time, mortality and a decrease in prepupal mass loss. Temperature significantly affected all studied traits except survival, prepupal fat content and adult longevity, and notably modified the larval density effects on prepupal mass, pupal mass, adult mass, prepupal-to-pupal mass loss, prepupal fat content, duration of larval period, and adult longevity. Males and females differed in all studied life-history traits except adult mass. We conclude that density and temperature and their interaction-related effects during larval development considerably affect BSF larval life-history traits. Therefore, these effects should be carefully considered when planning for insect mass rearing.
Relevance of Sex-Specific Metabolic Phenotypes in Diagnosis and Treatment of Mood Disorders and PTSD
Authors: Henry Stefanie S. , Ross Rachel A. , Rasgon Natalie
Published: January 2022

Mood disorders and post-traumatic stress disorder (PTSD) are considered brain-based illnesses, but they present with somatic symptoms and are often comorbid with insulin resistance. Peripheral and central mechanisms implicate the hypothalamus as a center for bi-directional communication of stress between the brain and body. The hypothalamic-pituitary-adrenal axis and the hypothalamic-pituitary-gonadal axis regulate glucocorticoid levels, yielding sex differences in stress response in addition to differences in PTSD and mood disorder susceptibility and course in males and females. Glucocorticoids and gonadal hormones modulate inflammatory response via cytokine receptor coupling, yielding multiple mechanisms connecting neuroinflammation and disturbances of mood and metabolism. Reduction of metabolic and psychologic stress via pharmacologic and behavioral interventions should be applied with attention to the commonalities and the heterogeneity in pathophysiology of these comorbid conditions across metabolic and sex-related phenotypes.

[
Psychiatr Ann
. 2022;52(1):20–25.]
Acquired Esotropia in an Adolescent Wearing Orthokeratology Lenses
Authors: Chung Seung Ah , Choi Young Joon , Kwak Jung Joon
Published: January 2022

Orthokeratology is a procedure involving the use of reverse-geometry lenses to temporarily correct refractive errors. Switching from spectacles to orthokeratology lenses may influence binocular visual function and accommodation. This is the first report of orthokeratology lens–associated acquired esotropia, a form of distance esotropia, in an adolescent with myopic anisometropia.

[
J Pediatr Ophthalmol Strabismus
. 2022;59(1):e7–e10.]
Exact controllability to eigensolutions of the bilinear heat equation on compact networks
Authors: Cannarsa Piermarco , Duca Alessandro , Urbani Cristina
Published: January 2022

Partial differential equations on networks have been widely investigated in the last decades in view of their application to quantum mechanics (Schrödinger type equations) or to the analysis of flexible structures (wave type equations). Nevertheless, very few results are available for diffusive models despite an increasing demand arising from life sciences such as neurobiology. This paper analyzes the controllability properties of the heat equation on a compact network under the action of a single input bilinear control.

By adapting a recent method due to [F. Alabau-Boussouira, P. Cannarsa, C. Urbani, Exact controllability to eigensolutions for evolution equations of parabolic type via bilinear control, arXiv: 1811.08806], an exact controllability result to the eigensolutions of the uncontrolled problem is obtained in this work. A crucial step has been the construction of a suitable biorthogonal family under a non-uniform gap condition of the eigenvalues of the Laplacian on a graph. Application to star graphs and tadpole graphs are included.
Robust dynamic sliding mode control design for interval type-2 fuzzy systems
Authors: Kavikumar Ramasamy , Kaviarasan Boomipalagan , Lee Yong-Gwon , Kwon Oh-Min , Sakthivel Rathinasamy , Choi Seong-Gon
Published: January 2022

This paper discusses the problem of stabilization of interval type-2 fuzzy systems with uncertainties, time delay and external disturbance using a dynamic sliding mode controller. The sliding surface function, which is based on both the system's state and control input vectors, is used during the control design process. The sliding mode dynamics are presented by defining a new vector that augments the system state and control vectors. First, the reachability of the addressed sliding mode surface is demonstrated. Second, the required sufficient conditions for the system's stability and the proposed control design are derived by using extended dissipative theory and an asymmetric Lyapunov-Krasovskii functional approach. Unlike some existing sliding mode control designs, the one proposed in this paper does not require the control coefficient matrices of all linear subsystems to be the same, reducing the method's conservatism. Finally, numerical examples are provided to demonstrate the viability and superiority of the proposed design method.
Efficient time second-order SCQ formula combined with a mixed element method for a nonlinear time fractional wave model
Authors: Yang Yining , Liu Yang , Wen Cao , Li Hong , Wang Jinfeng
Published: January 2022

In this article, a kind of nonlinear wave model with the Caputo fractional derivative is solved by an efficient algorithm, which is formulated by combining a time second-order shifted convolution quadrature (SCQ) formula in time and a mixed element method in space. The stability of numerical scheme is derived, and an optimal error result for unknown functions which include an original function and two auxiliary functions are proven. Further, the numerical tests are conducted to confirm the theoretical results.
Vulnerabilidad demográfica y distancia a grandes ciudades: Consecuencias sobre la población adulta-joven en Castilla y León
Authors: López González Alejandro
Published: January 2022

En los últimos años es un tema de debate en la sociedad española la extrema despoblación de amplios espacios de nuestra geografía, cobrando gran protagonismos expresiones como la “España vaciada” o la “Laponia española”. En este contexto se ha planteado la hipótesis de una segunda despoblación, complementaria de una primera asociada al éxodo rural, protagonizada por jóvenes residentes en ciudades de las regiones que forman la España interior. Teniendo presente estas propuestas se ha diseñado una metodología que parte de una primera clasificación de los municipios de Castilla y León en función de su grado de vulnerabilidad demográfica, seguida de la aplicación de un modelo autorregresivo espacial que pretende medir el impacto sobre el porcentaje de población de edades entre 20 y 39 años de la distancia a Madrid y a Valladolid, considerando estas ciudades como potenciales receptoras de la población joven que emigran desde los municipios de donde son originarios. Los resultados obtenidos apuntan a unos resultados híbridos, el impacto es mayor sobre los municipios de carácter rural y sobre las cabeceras comarcales clásicas, pero no son tan claros sobre las cohortes adulto-jóvenes residentes en las ciudades medias, así como tampoco en los municipios económicamente más dinámicos.
Institucionalização de hábitos e rotinas na implementação do sistema público de escrituração digital em uma prestadora de serviços contábeis
Authors: Dos Santos Vanderlei , Cardoso Jéssica Suyan , Beck Franciele , Beuren Ilse Maria
Published: January 2022

O estudo objetiva verificar o processo de institucionalização de hábitos e rotinas com a implementação do Sistema Público de Escrituração Digital (SPED) em uma empresa prestadora de serviços contábeis, a partir da análise em profundidade deste fenômeno. Pesquisa com abordagem qualitativa foi realizada, pautada no modelo de institucionalização de hábitos e rotinas proposto por Burns e Scapens (2000). A pesquisa se insere na discussão acerca do processo de institucionalização de hábitos e rotinas e as implicações do sistema público de escrituração digital em pequenas empresas, sob a lente de diferentes usuários de uma prestadora de serviços contábeis e de seus clientes, além de áreas e módulos distintos do SPED. As evidências sugerem que em função da complexidade das mudanças e necessidade de envolvimento entre a empresa prestadora de serviços contábeis e seus clientes, houve dispêndio de mais recursos no processo de institucionalização. Não se observou consenso na empresa investigada a respeito dos estágios de codificação, incorporação, reprodução e institucionalização do SPED, mas constatou-se indícios de resistência, seja pela falta de conhecimento do processo, ou pelo simples apego às rotinas. O estudo contribui para a literatura ao confirmar por meio de evidências empíricas que assim como ficam evidentes a caracterização do estágio de codificação, também se observa indícios de atendimento aos requisitos de institucionalização, propostos por Burns e Scapens (2000). Evidencia também a importância de planejar a implementação do SPED, de modo a garantir uma visão completa e concisa de todo o processo e suas implicações.
La prospettiva etica nella Conferenza ONU di Pechino sulla donna
Authors: Elliott Peter J.
Published: January 2022

L'articolo analizza quale sia stata l'etica dominante durante i lavori della recente IV Conferenza Internazionale sulla Donna svoltasi a Pechino dal 4 al 15 settembre 1995. In generale, durante tutte le Conferenze Onu - ed anche la manifestazione di Pechino non fa eccezione - ci si riferisce ad un'etica basata sul consenso fra tutte le nazioni secondo il principio del "minimo comun denominatore". Da questa premessa, ne deriva il ruolo importante svolto dai sostenitori di un'etica imperniata sul pragmatismo e l'utilitarismo, i quali rifiutano qualsiasi fondazione metafisica o religiosa. A queste correnti di pensiero si rifanno anche i movimenti femministi che a Pechino hanno improntato la stesura del documento finale (Piatform for Action). In esso traspare l'individualismo liberale che privilegia l'autonomia e l'autodeterminazione della donna, la quale può, ad esempio, arrivare al punto di negare al nascituro il diritto alla vita, perché considerato parte del corpo della donna e, quindi, ad essa soggetto. Termini come reproductive rights, reproductive health, fertility control, sexual rights, sexual orientation sono stati proposti durante la Conferenza secondo la logica sopra illustrata. Gli stessi diritti umani, così, non sono considerati giustamente quali principi universali fondati sul diritto naturale, bensì come adattamenti, vantaggi o privilegi concessi alle persone secondo il consenso sociale e lo sviluppo delle leggi. La Santa Sede - che ha partecipato sia alla fase preparatoria che ai lavori della Conferenza di Pechino - non ha mancato di far sempre presente - sia in riferimento al Documento preparatorio che alla Pllltfonn for Action - tutte le proprie riserve sulle dichiarazioni che non rispondono al pieno rispetto del principio dell'inviolabilità della vita umana fin dal momento del suo concepimento e dell'inalienabilità della dignità di ciascun individuo.
Influence of Pre-Pregnancy Underweight Body Mass Index on Fetal Abdominal Circumference, Estimated Weight, and Pregnancy Outcomes in Gestational Diabetes Mellitus
Authors: Kim Minji , Hur Kyu-Yeon , Choi Suk-Joo , Oh Soo-Young , Roh Cheong-Rae
Published: January 2022

This study aimed to determine the influence of pre-pregnancy body mass index on pregnancy outcomes in gestational diabetes mellitus (GDM), comparing underweight patients with GDM with normal weight patients with GDM. Maternal baseline characteristics, ultrasonographic results, and pregnancy and neonatal outcomes were reviewed in 946 women with GDM with singleton pregnancies. Underweight patients with GDM showed a benign course in most aspects during pregnancy, except for developing a higher risk of giving birth to small for gestational age neonates. Underweight women with GDM required less insulin treatment, had a higher rate of vaginal delivery, and had a lower rate of cesarean delivery. In addition, their neonates were more likely to have fetal abdominal circumference and estimated fetal weight below the 10th percentile both at the time of GDM diagnosis and before delivery. Notably, their risk for preeclampsia and macrosomia were lower. Collectively, our data suggest that underweight women with GDM may require a different approach in terms of diagnosis and management throughout their pregnancy.
Glucose Profiles Assessed by Intermittently Scanned Continuous Glucose Monitoring System during the Perioperative Period of Metabolic Surgery
Authors: Kim Kyuho , Choi Sung Hee , Jang Hak Chul , Park Young Suk , Oh Tae Jung
Published: January 2022

Background: Continuous glucose monitoring (CGM) has been widely used in the management of diabetes. However, the usefulness and detailed data during perioperative status were not well studied. In this study, we described the immediate changes of glucose profiles after metabolic surgery using intermittently scanned CGM (isCGM) in individuals with type 2 diabetes mellitus (T2DM).Methods: This was a prospective, single-center, single-arm study including 20 participants with T2DM. The isCGM (FreeStyle Libre CGM) implantation was performed within 2 weeks before surgery. We compared CGM metrics of 3 days before surgery and 3 days after surgery, and performed the correlation analyses with clinical variables.Results: The mean glucose significantly decreased after surgery (147.0±40.4 to 95.5±17.1 mg/dL, P<0.001). Time in range (TIR; 70 to 180 mg/dL) did not significantly change after surgery in total. However, it was significantly increased in a subgroup of individuals with glycosylated hemoglobin (HbA1c) ≥8.0%. Time above range (>250 or 180 mg/dL) was significantly decreased in total. In contrast, time below range (<70 or 54 mg/dL) was significantly increased in total and especially in a subgroup of individuals with HbA1c <8.0% after surgery. The coefficient of variation significantly decreased after surgery. Higher baseline HbA1c was correlated with greater improvement in TIR (rho=0.607, P=0.005).Conclusion: The isCGM identified improvement of mean glucose and glycemic variability, and increase of hypoglycemia after metabolic surgery, but TIR was not significantly changed after surgery. We detected an increase of TIR only in individuals with HbA1c ≥8.0%.
Pseudotumor Cerebri Syndrome (PTCS), Clinico-Radiological Profile
Authors: Singh Ranjeet Kumar , Kumar Anand , Singh Varun Kumar , Pathak Abhishek , Chaurasia Rameshwar Nath , Mishra Vijaya Nath , Joshi Deepika
Published: January 2022

Objectives:

The aim of the study was to classify patients of Pseudotumor Cerebri Syndrome (PTCS) on the basis of newer classification along with its clinico-radiological correlations.

Patients and Methods:

A prospective study was conducted at a tertiary care teaching hospital. A total of 25 consecutive patients who fulfilled the new diagnostic criteria for PTCS were enrolled after taking informed written consent. A thorough clinical history, neurological examination and neuroimaging was carried out. Patients were classified into Primary and Secondary PTCS followed by Definite, Probable and Suggested as per new nomenclature.

Results:

Out of 25 patients, there were 9 patients in the primary PTCS group and 16 in the secondary PTCS group. Mean duration of symptoms was 40.84 ± 45.68 days. Primary PTCS group patients were significantly overweight and had higher BMI as compared to the secondary group with significant number of patients reporting recent rapid weight gain. The CSF pressure and protein were non-significantly higher in the primary PTCS group. We could classify 17 (68%) patients in our study as definite PTCS, 7 (28%) as probable PTCS and suggested PTCS in one patient. In secondary PTCS group there were 16 (64%) patients. APLA positivity was found to be the most common etiology for secondary PTCS with statistical significance (P = 0.025).

Conclusions:

Early recognition along with appropriate classification and prompt treatment can prevent vision loss in PTCS. Apart from obesity, recent weight gain is also closely related with primary PTCS.
Evaluation of Selenium Supplementation in Acute Ischemic Stroke Outcome
Authors: Sharifi-Razavi Athena , Karimi Narges , Jafarpour Hamed
Published: January 2022

Background:

Selenium is a trace element that protects against cellular damage by oxygen radicals through selenoproteins. Ischemic stroke is associated with the generation of oxygen free radicals resulting in a condition of oxidative stress.

Objectives:

The present study aimed to evaluate the effect of selenium supplementation on short-term and long-term acute ischemic stroke outcomes.

Methods:

This was a randomized, parallel, outcome assessor blind, placebo-controlled feasibility study on ischemic stroke patients admitted in Bou-Ali Sina Hospital, Sari, Iran (2015–2017). Inclusion criteria were adults with accepted ischemic stroke by neuroimaging during the last 72h with a volume of at least one-third of MCA territory. The primary outcome was the short-term outcome measuring with the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS) on day 7. The participants (44 patients) were randomized into two groups (22 in each group), one receiving intravenous selenium selenite for 5 days, and the other 40 cc normal saline as a placebo.

Results:

A total of 40 ischemic stroke patients (18 females, 22 males) with mean age of 68.2 ± 10 years were investigated. Selenium supplementation improved short-term outcome, 15.7% by using NIHSS (66% vs 42%, RR = 0.85 with CI = 0.54-1.35; NNT = 10; 95% CI = 5.15- 2.53, P = 0.51) and 46.3% by using mRS (57% vs 12%, RR = 0.52 with CI = 0.31-0.88; NNT = 3; 95% CI = 1.49 -7.59, P = 0.01). The long-term outcome did not change significantly by considering Barthel index >75 after 3 months in comparison to comparator group (33.3% vs 29.4%, RR = 1.13 with CI = 0.40-3.16; NNT = 26; 95% CI = 2.77 -3.54, P = 0.81].

Conclusions:

Selenium selenite supplementation in acute ischemic stroke can improve short-term outcome but cannot influence the long-term outcome.
Is Video-Oculography a Predictive Test for Myasthenia Gravis with Ocular Symptoms?
Authors: Sirin Tuba Cerrahoglu , Karaaslan Zerrin , Arkali Burcu N , Bekdik Pınar , Akinci Tuba , Candan Fatma , Akarsu Emel Oguz , Baslo M Baris , Orhan Elif Kocasoy , Oge A Emre
Published: January 2022

Background and Objective:

The aim of this study was to evaluate the contribution of extraocular muscle function testing with video-oculography (VOG), which is a noninvasive and easily applicable method of recording eye movement with digital cameras, to the diagnosis of myasthenia gravis (MG) in patients without any clinical eye movement abnormalities.

Methods and Materials:

The study included 18 patients prediagnosed with ocular MG: MG Group (N = 7) with abnormal, and non-MG Group (N = 11) with normal single-fiber electromyography. Control group included 50 healthy volunteers. Ocular movements were recorded with the EyeSeeCam VOG device.

Results:

The inward latency of the 10° horizontal saccade and the downward latency of the 10° vertical saccade were significantly delayed; and the downward amplitude of the 10° vertical saccade was significantly lower in the MG group. Receiver operating characteristic curve analyses showed high specificity values for the discrimination of MG patients.

Conclusions:

This study supports the usefulness of the VOG device in revealing subclinical extraocular muscle involvement in MG.
Predictors of Outcome in Spontaneous Intracerebral Hemorrhage with Special Reference to Hyponatremia
Authors: Porwal Tulika , Mohanty Smita
Published: January 2022

Objective:

The study was done to find the various clinical, biochemical and radiological predictors of outcome in spontaneous intracerebral hemorrhage (SICH) patients and to assess the role of hyponatremia as a predictor of in-hospital mortality.

Materials and Methods:

This was a hospital based prospective observational study conducted in the department of Medicine, VMMC and Safdarjang Hospital, New Delhi, India on 75 adults (>18 years of age, both male and female) presenting with SICH. Various parameters comprising demographic, clinical, laboratory, and radiological variables along with stroke severity were assessed and studied as predictors of in-hospital outcome, i.e., mortality and disability at the time of discharge as assessed by modified Rankin's Scale (mRS) in 75 SICH patients presenting to the emergency department. Furthermore, the role of hyponatremia as a predictor of in-hospital mortality was studied.

Results:

Out of 75 patients enrolled in the study, 40% (n = 30) of the patients died in the hospital and 60% (n = 45) were discharged. Out of the discharged category, 80% (n = 36) had mild disability with mRS 1–3 and 20% (n = 9) had moderate-to-severe disability with mRS 4-5. National Institute of Health Stroke Scale (NIHSS) at the time of hospitalization was found to be the significant independent predictor of in-hospital mortality and higher mRS score at discharge. Furthermore, Glasgow Coma Scale (GCS) ≤4 and NIHSS >12 were significantly associated with in-hospital mortality. Hyponatremia was found in 44% (n = 33) of the patients at the time of hospitalization and out of them sodium level got corrected in 15.15% (n = 5). Out of the 42 normonatremic patients 31% (n = 13) developed hyponatremia in subsequent days during hospitalization. No association was found between hyponatremia and in-hospital mortality.

Conclusion:

Our study highlights the fact that SICH is associated with high in-hospital mortality. NIHSS score at the time of hospitalization is an independent predictor of in-hospital mortality and disability at discharge. Furthermore, GCS ≤4 and NIHSS >12 are significantly associated with in-hospital mortality. Although hyponatremia is a common occurrence in patients with SICH, our study failed to show association between hyponatremia and in-hospital mortality.
Aortic Elasticity Indices as Predictors of Coronary Artery Disease Severity Assessed by SYNTAX Score
Authors: El-Naggar Heba M. , Anwar Helen S. , Helmy Hatem A. , Demitry Salwa R.
Published: January 2022

Background:

Aortic elastic properties have been related to coronary artery disease (CAD) morbidity and mortality. We aimed to assess the relation of aortic elasticity indices to the severity and complexity of CAD assessed using the SYNTAX Score (SS), evaluating which of these indices have better predictivity for CAD severity.

Materials and Methods:

We prospectively enrolled 150 individuals who underwent elective coronary angiography for suspected CAD, out of them 29 (19.3%) had normal or nonsignificant angiographic findings (Group I), whereas 121 (80.7%) had significant CAD (Group II) for whom the SS was calculated. Echo-derived aortic elasticity indices were performed for all patients.

Results:

Logistic regression analyses showed that each of aortic distensibility, stiffness index, elastic modulus, aortic strain, and aortic peak early diastolic velocity were predictors for significant CAD and further for more complex CAD as indicated by intermediate-high SS. Receiver operator characteristic curves-derived cutoff points were performed for each of the aortic elasticity indices. Along with diabetes, decreased aortic strain ≤10.2% was the only independent predictor of intermediate-high SS (odds ratio = 4.31, 95% confidence interval = 1.38–13.50, P = 0.01).

Conclusion:

Simple M-mode derived aortic elasticity indices, particularly aortic strain ≤10.2%, might predict patients with more severe and complex CAD.
A Subtle Decline in Cardiac Mechanics is correlated with Albuminuria in Asymptomatic Normotensive Patients with Type 2 Diabetes Mellitus
Authors: Abdellatif Yasser A , Nazmy Nour Eldin M. , Bastawy Islam M. , Raafat Sameh S.
Published: January 2022

Background:

Type 2 diabetes mellitus (T2DM) insidiously affects the myocardium with subsequent cardiomyopathy and induces microvascular damage in the kidneys reflected by albuminuria. We aimed to investigate the relationship between albuminuria and subclinical left ventricular (LV) systolic dysfunction in asymptomatic normotensive patients with T2DM assessed by two-dimensional speckle-tracking echocardiography.

Materials and Methods and Results:

Sixty normotensive patients with T2DM were included and subdivided into two subgroups, each including thirty patients according to the presence of albuminuria, together with thirty control subjects. All underwent echocardiographic examination, including LV regional and global longitudinal strain (GLS) measurements. Laboratory tests were withdrawn, including serum glycated hemoglobin (HbA1C) and albumin–creatinine ratio (ACR). When compared to the control group, patients with T2DM had a significantly lower average peak systolic LV GLS (−16.18% ± 2.78% vs. −18.13% ± 2.86%, P < 0.001), however, there was no significant difference in average peak systolic LV GLS between both diabetic subgroups (−15.57% ± 2.77% in the albuminuric subgroup vs. −16.79% ± 2.70% in the nonalbuminuric subgroup, P = 0.077). Moreover, there was a significant correlation between ACR and reduction of GLS in patients with T2DM and albuminuria (r = 0.55, P = 0.002). However, this correlation was absent in patients with T2DM without albuminuria (r = 0.107, P = 0.573).

Conclusions:

Patients with T2DM have subclinical LV systolic dysfunction with a reduction of average LV GLS that correlates with ACR in patients with T2DM and albuminuria.
Left Atrial Volume Index to Left Ventricular Ejection Fraction Ratio Predicted Major Adverse Cardiovascular Event in ST-Elevated Myocardial Infarction Patients during 8 Years of Follow-up
Authors: Yilmaz Ahmet Seyda , Kahraman Fatih , Ergül Elif , Çetin Mustafa
Published: January 2022

Objective:

It is crucial to determine the high-risk group in ST-elevated myocardial infarction (STEMI). Left ventricle ejection fraction (LVEF) and left atrial volume index (LAVI) are the well-established parameters for risk prediction. However, major adverse cardiovascular events (MACEs) may be predicted less than actual when LVEF or LAVI are in the normal range. It was investigated LAVI to LVEF ratio (LAVI/LVEFr) for more accurate MACE prediction.

Methods:

Patients with STEMI were included in the study. LAVI and LVEF were obtained at admission. The LAVI/LVEFr was calculated as LAVI dividing by LVEF. The composite primary endpoint of the study was all-cause mortality and new-onset heart failure for 8 years follow-up.

Results:

A total of 176 patients were divided into two groups according to the presence of MACE. MACE (+) group consisted of 70 (39.7%) patients who were older and more likely to be male. While LVEF (P < 0.001) was lower, LAVI (P < 0.001) and LAVI/LVEFr (P < 0.001) were higher in MACE (+) group. Age (P = 0.003), serum creatinine (P < 0.001), and LAVI/LVEFr (P < 0.001) were independent predictors of MACE.

Conclusion:

Combined usage of LAVI and LVEF (LAVI/LVEFr), increased age, and serum creatinine level were the independent predictors of MACE during 8 years of follow-up in STEMI patients.
Assessment of Intra and Extra-Hospital Outcome after Takotsubo Syndrome in a Single-Center Population
Authors: Licordari Roberto , Manganaro Roberta , Cusmà-Piccione Maurizio , Dattilo Giuseppe , Citro Rodolfo , Khandheria Bijoy K. , Bella Gianluca Di , Zito Concetta
Published: January 2022

Objectives:

To evaluate short- and long-term outcome in a single prospective cohort of Takotsubo syndrome (TTS) patients, trying to early identify those with better prognosis and to assess the prevalence of left ventricular ejection fraction (LVEF) recovery over time.

Methods:

Forty-nine patients prospectively enrolled underwent to assessment of demographic, clinical, and echocardiographic characteristics, and later were followed to identify the outcomes during a mean follow-up (FU) of 93 months. At the end of the FU phase, a subgroup of patients underwent to a clinical and echocardiographic re-evaluation. As major adverse cardiac events (MACE) were considered: Intra and extra-hospital death, re-hospitalizations for acute heart failure or atrial fibrillation (AF) or acute myocardial infarction (AMI) and TTS recurrence; minor events were considered minor symptoms of heart failure and angina not requiring hospitalization.

Results:

The prevalence of re-hospitalizations (MACE) over time was: 41% (n = 12) for HF; 6.8% (n = 2) for AMI; 3.4% (n = 1) for TTS relapse and 20% (n = 6) for AF. Minor events were the symptoms of chest pain and dyspnea not requiring hospitalization in 6 (20.7%) and 12 (34.4%) patients, respectively. LVEF at the time of admission was predictor for MACE. Stratifying patients on the LVEF admission median value (40%). Patients with LVEF <40% at admission had a significantly lower survival free from adverse cardiac events compared to patients with LVEF ≥40%. Twenty-seven (93%) patients underwent to a clinical reassessment with electrocardiogram and echocardiographic examination. LVEF value showed a statistically significant increase (P = 0.004) at the end of FU.

Conclusions:

At admission, “high-risk” patients (LVEF <40%) can be easily detected, allowing an appropriate pharmacological and/or mechanical support strategy and a more “careful” FU.